BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0628.p (330 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0563 Non COG 336 4e-92 NMB0276 [R] COG0429 Predicted hydrolase of the alpha/beta-hydrol... 218 1e-56 NMA2211 [R] COG0429 Predicted hydrolase of the alpha/beta-hydrol... 212 8e-55 STM3462 [R] COG0429 Predicted hydrolase of the alpha/beta-hydrol... 199 9e-51 PA0368 [R] COG0429 Predicted hydrolase of the alpha/beta-hydrola... 194 2e-49 >RSc0563 Non COG Length = 371 Score = 336 bits (862), Expect = 4e-92, Method: Compositional matrix adjust. Identities = 179/327 (54%), Positives = 218/327 (66%), Gaps = 15/327 (4%) Query: 6 PRWLPGGHLQTIYPSTCLPKPELAYRRERWEAPDGDFIDIDFV--DGQPGRPLLVLFHGL 63 P WL GG+ QTI P+ P +AYRRERW+ PDGDFID+D+ + PL+VLFHGL Sbjct: 31 PWWLIGGNAQTIVPARLWRFPRIAYRRERWDTPDGDFIDLDWTTHEADAHTPLVVLFHGL 90 Query: 64 EGSSDSHYSRALMAEVQRRGWHGAIPHFRGCSGEINLAPRFYHSGDSAELDWIIRRLKLR 123 EG S SHY++ +M ++ R W G +PHFRGCSGE+N APR YHSGDSAE+ WI+ RL Sbjct: 91 EGDSRSHYAQLMMDALRARRWPGVVPHFRGCSGELNRAPRMYHSGDSAEIAWILDRLYRT 150 Query: 124 QQDLAATHLYACGVSLGANALLRWLGESQHEAEIVDAACAVSAPLDLAGGGTALASGFNR 183 L A G+SLG N LLR LGE +A + AA VSAPLD+ GG AL+ GF Sbjct: 151 HCAPHGRKLLAVGISLGGNMLLRHLGERGADARQLSAAATVSAPLDMMAGGAALSQGFGM 210 Query: 184 LYTWVFLRTLRPKCLAKLEQFPGLFDRDALLAARDLYAFDNVVTAPLHGYRNTDDYWDRA 243 LYT +FLRTL+ K AKL+Q PGL+DR A+LAAR FDN+VTAPLHGYRN DYW RA Sbjct: 211 LYTRMFLRTLKQKAAAKLDQHPGLYDRHAMLAARSFVEFDNLVTAPLHGYRNVYDYWTRA 270 Query: 244 SAKHILHDISVPTLVLNAQNDPFLPARHL--PRSAAPEVVLEYPAQGGHVGFAAGGP--- 298 S+K +L D+ VP LVLNA+NDPFLP RHL P +P+VVL+ P GGHVGF Sbjct: 271 SSKPVLRDVRVPVLVLNARNDPFLPGRHLPGPGDVSPDVVLDQPLHGGHVGFLMRRDGKL 330 Query: 299 -----PGSLEWLPRRLLHFLE---GRT 317 G ++W+P RLL F + GRT Sbjct: 331 RHLPLAGRIDWMPARLLRFFDDVLGRT 357 >NMB0276 [R] COG0429 Predicted hydrolase of the alpha/beta-hydrolase fold Nme Neisseria meningitidis MC58 Length = 318 Score = 218 bits (556), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 140/323 (43%), Positives = 182/323 (56%), Gaps = 21/323 (6%) Query: 1 MLYIPPR---WLPGGHLQTIYPSTCLPKPELAYRRERWEAPDGDF-IDIDFVDG-QPGRP 55 M+ PP +L G+ TI + L +P AYRRE G + DF DG P P Sbjct: 1 MILTPPDTPFFLRNGNADTI-AAKFLQRPAPAYRRELLPDSTGKTKVAYDFSDGISPDAP 59 Query: 56 LLVLFHGLEGSSDSHYSRALMAEVQRRGWHGAIPHFRGCSGEINLAPRFYHSGDSAELDW 115 L+VLFHGLEGSS SHY+ LM V+ RGWHG + HFR C G N AP FYH GD+AE+ + Sbjct: 60 LVVLFHGLEGSSRSHYAVELMLAVRDRGWHGVVVHFRSCGGIANTAPVFYHLGDTAEIAF 119 Query: 116 IIRRLKLRQQDLAATHLYACGVSLGANALLRWLGESQHEAEIVDAACAVSAPLDLAGGGT 175 + R ++ +YA GVSLG NAL ++LGE Q + + AA +SAP+D G Sbjct: 120 TLDTFAARYRE-----IYAVGVSLGGNALAKYLGE-QGKKALPQAAAVISAPVDAEAAGR 173 Query: 176 ALASGFNR-LYTWVFLRTLRPKCLAKLEQFPGLFDRDALLAARDLYAFDNVVTAPLHGYR 234 SG R LYT FLRTL PK L+ F F + L FD+ TAPLHG+ Sbjct: 174 RFDSGITRLLYTRYFLRTLIPKA-KSLQGFQTAF----AAGCKTLGEFDDRFTAPLHGFA 228 Query: 235 NTDDYWDRASAKHILHDISVPTLVLNAQNDPFLPARHLPRS--AAPEVVLEYPAQGGHVG 292 + DY+ + S K +L ++ P L+LNA NDPFLP LPR+ + V L PA GGHVG Sbjct: 229 DRHDYYRQTSCKPLLKHVAKPLLLLNAVNDPFLPPEALPRADEVSEAVTLFQPAYGGHVG 288 Query: 293 FAAG-GPPGSLEWLPRRLLHFLE 314 F + G L+WLP+ +L + + Sbjct: 289 FVSSTGGRLHLQWLPQTVLSYFD 311 >NMA2211 [R] COG0429 Predicted hydrolase of the alpha/beta-hydrolase fold NmA Neisseria meningitidis Z2491 Length = 318 Score = 212 bits (540), Expect = 8e-55, Method: Compositional matrix adjust. Identities = 138/323 (42%), Positives = 180/323 (55%), Gaps = 21/323 (6%) Query: 1 MLYIPPR---WLPGGHLQTIYPSTCLPKPELAYRRERWEAPDGDF-IDIDFVDG-QPGRP 55 M+ PP +L G+ TI + L + AYRRE G DF DG P P Sbjct: 1 MILTPPDTPFFLRNGNADTI-AAKFLQRSAPAYRRELLPDSTGKTKTAYDFSDGISPDAP 59 Query: 56 LLVLFHGLEGSSDSHYSRALMAEVQRRGWHGAIPHFRGCSGEINLAPRFYHSGDSAELDW 115 L+VLFHGLEG S SHY+ LM V+ RGW+G + HFR C G N AP FYH GD+AE+ + Sbjct: 60 LVVLFHGLEGGSGSHYAVELMLAVRDRGWNGVVVHFRSCGGVANTAPVFYHLGDTAEIAF 119 Query: 116 IIRRLKLRQQDLAATHLYACGVSLGANALLRWLGESQHEAEIVDAACAVSAPLDLAGGGT 175 + L R ++ +YA GVSLG NAL ++LGE Q E + AA +SAP+D G Sbjct: 120 TLDTLAARYRE-----IYAVGVSLGGNALAKYLGE-QGENALPQAAAVISAPVDAEAAGN 173 Query: 176 ALASGFNR-LYTWVFLRTLRPKCLAKLEQFPGLFDRDALLAARDLYAFDNVVTAPLHGYR 234 SG R LYT FLRTL PK + L+ F F + L FD+ TAPLHG+ Sbjct: 174 RFDSGITRLLYTRYFLRTLIPKARS-LQGFQTAF----AAGCKTLGEFDDRFTAPLHGFA 228 Query: 235 NTDDYWDRASAKHILHDISVPTLVLNAQNDPFLPARHLPRS--AAPEVVLEYPAQGGHVG 292 + DY+ + S K +L ++ P L+LNA NDPFLP LPR+ + V L P GGHVG Sbjct: 229 DRHDYYRQTSCKPLLKHVAKPLLLLNAVNDPFLPPEALPRADEVSEAVTLFQPTHGGHVG 288 Query: 293 FA-AGGPPGSLEWLPRRLLHFLE 314 F + G L+WLP+ +L + + Sbjct: 289 FVGSTGGRLHLQWLPQTVLSYFD 311 >STM3462 [R] COG0429 Predicted hydrolase of the alpha/beta-hydrolase fold Sty Salmonella typhimurium LT2 Length = 355 Score = 199 bits (505), Expect = 9e-51, Method: Compositional matrix adjust. Identities = 121/325 (37%), Positives = 178/325 (54%), Gaps = 11/325 (3%) Query: 3 YIPPRWLPGGHLQTIYPSTCLPKPELAYRRERWEAPDGDFIDIDFV-DGQPGR--PLLVL 59 +IP R + HLQT+ P K + +R E PDGDF+D+ + D Q + P LV+ Sbjct: 34 FIPMRGIRNRHLQTMLPRLIRRKVKFNAHWQRLELPDGDFVDLAWSEDPQQAKYKPRLVV 93 Query: 60 FHGLEGSSDSHYSRALMAEVQRRGWHGAIPHFRGCSGEINLAPRFYHSGDSAELDWIIRR 119 FHGLEGS +S Y+ L+ Q+RGW G + HFRGCSGE N R YHSG++ + W +R Sbjct: 94 FHGLEGSLNSPYAHGLIEAAQKRGWLGVVMHFRGCSGEPNRLNRIYHSGETEDGAWFLRW 153 Query: 120 LKLRQQDLAATHLYACGVSLGANALLRWLGESQHEAEIVDAACAVSAPLDLAGGGTALAS 179 L Q++ A A G SLG N L L + + I +AA VSAP L + Sbjct: 154 L---QREFGAVPTAAVGYSLGGNMLACLLAKEGRDIPI-EAAVIVSAPFVLEACSYHMDK 209 Query: 180 GFNRLYTWVFLRTLRPKCLAKLEQFPGLF--DRDALLAARDLYAFDNVVTAPLHGYRNTD 237 GF+R+Y L L+ KL +PG + L + R + FD+++TA +HG+ + Sbjct: 210 GFSRVYQRYLLNLLKANASRKLAAYPGSLPVNLAQLKSMRRIREFDDLITAKIHGFADAI 269 Query: 238 DYWDRASAKHILHDISVPTLVLNAQNDPFLPARHLPRSA--APEVVLEYPAQGGHVGFAA 295 DY+ + SA +L+ I+ PTL+++A++DPF+ +P++ P+V + GGHVGF Sbjct: 270 DYYRQCSAMPLLNQIAKPTLIIHAKDDPFMDHHVIPKAEDLPPQVEYQLTEHGGHVGFIG 329 Query: 296 GGPPGSLEWLPRRLLHFLEGRTESS 320 G P WL RR+ +L E+S Sbjct: 330 GTPLRPEMWLERRIPDWLTTYLEAS 354 >PA0368 [R] COG0429 Predicted hydrolase of the alpha/beta-hydrolase fold Pae Pseudomonas aeruginosa Length = 332 Score = 194 bits (494), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 125/326 (38%), Positives = 173/326 (53%), Gaps = 16/326 (4%) Query: 3 YIPPRWLPGGHLQTIYPSTCLPKPELAYRRERWEAPDGDFIDIDFVDGQPGR-PLLVLFH 61 + P WLP HLQT++ P L +RER DGDFID+D+ PL++ H Sbjct: 7 FQPAWWLPNPHLQTLWSPFFRRGPTLERQRERLWLADGDFIDLDWAGPHDAETPLVLALH 66 Query: 62 GLEGSSDSHYSRALMAEVQRRGWHGAIPHFRGCSGEINLAPRFYHSGDSAELDWIIRRLK 121 GL GSS SHY L + RGW ++RGCSGE N PR YHSG S +L ++ L+ Sbjct: 67 GLTGSSSSHYILGLQRALLERGWASVALNWRGCSGEPNRLPRGYHSGVSDDLAEVVAHLR 126 Query: 122 LRQQDLAATHLYACGVSLGANALLRWLGESQHEAEIVDAACAVSAPLDLAGGGTALASGF 181 R+ LYA G SLG N LL++LGE+ + ++ AVS P L + GF Sbjct: 127 ARRPQ---APLYAVGYSLGGNVLLKYLGETAGDCPLL-GGVAVSVPFRLDECADRIGLGF 182 Query: 182 NRLYTWVFLRTLRPKCLAKLEQFPGLFDRDALLA---------ARDLYAFDNVVTAPLHG 232 +R+Y F++ + K F + L A R + FD VTAPLHG Sbjct: 183 SRVYQAHFMKAMLAYVQDKQRLFGEQGQAEGLAALQRLGPLEGMRTFWDFDGRVTAPLHG 242 Query: 233 YRNTDDYWDRASAKHILHDISVPTLVLNAQNDPFLPARHLPRSA--APEVVLEYPAQGGH 290 + + DY+ RAS+++ L DI P+L++++ +DPF+ AR LP + AP LE A+GGH Sbjct: 243 FADARDYYRRASSRYYLPDIRTPSLIIHSSDDPFVFARSLPDRSELAPCTELELHARGGH 302 Query: 291 VGFAAGGPPGSLEWLPRRLLHFLEGR 316 VGF G P +L RR+ +LE R Sbjct: 303 VGFVDGSPRQPTYYLERRIPDWLEAR 328