BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0494.p (280 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value XF1717 [R] COG0325 Predicted enzyme with a TIM-barrel fold Xfa X... 344 1e-94 aq_274 [R] COG0325 Predicted enzyme with a TIM-barrel fold Aae A... 166 5e-41 BH2550 [R] COG0325 Predicted enzyme with a TIM-barrel fold Bha B... 163 5e-40 HI0090 [R] COG0325 Predicted enzyme with a TIM-barrel fold Hin H... 157 3e-38 PM0112 [R] COG0325 Predicted enzyme with a TIM-barrel fold Pmu P... 155 8e-38 >XF1717 [R] COG0325 Predicted enzyme with a TIM-barrel fold Xfa Xylella fastidiosa 9a5c Length = 266 Score = 344 bits (883), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 167/248 (67%), Positives = 196/248 (79%) Query: 29 RWPQATTVEDFRHNLAATQQRIVAACARVGRDPASVRLLPVSKTKSQAAIRLAYAAGCRM 88 R Q TVED R NL RI+AAC RV R P+SV LLPVSKT + IRL+Y AGCR Sbjct: 19 RGLQTLTVEDIRSNLTKVYSRIIAACQRVDRHPSSVTLLPVSKTVDEVHIRLSYEAGCRK 78 Query: 89 LGENKPQEAWQKWQALQDLPDLQWSVIGHLQTNKAKLVARFASEFQALDSLRLAEVLERR 148 LGENK Q+A+ KW+A+ DL DL WSVIGHLQTNKAKLVARFASEFQALDSLR+AE LERR Sbjct: 79 LGENKAQDAYHKWEAMSDLTDLHWSVIGHLQTNKAKLVARFASEFQALDSLRVAEALERR 138 Query: 149 LQIEGRGLDVLVQVNTSGEASKYGLEPDQVAPFLRQLRAFPALRLRGLMTLAVLSAEPER 208 LQIEGR LDVL+QVNTSGE +KYGL P++V F++ L A+PALR+RGLMTLA+LS + R Sbjct: 139 LQIEGRSLDVLIQVNTSGETNKYGLPPEEVVRFVQALSAYPALRVRGLMTLALLSGDTSR 198 Query: 209 VRPCFARLRQLRERLRQELPDGALLQDLSMGMSGDAEIAIEEGATVVRVGQAIFGARDVP 268 VR CF +LR LR+R++Q P G + +LSMGMSGD EIAIEEGATVVRVGQAI+GAR +P Sbjct: 199 VRQCFTQLRILRDRIQQASPQGHHITELSMGMSGDLEIAIEEGATVVRVGQAIYGARALP 258 Query: 269 DSHYWPTT 276 + H+ T Sbjct: 259 NLHFHHTV 266 >aq_274 [R] COG0325 Predicted enzyme with a TIM-barrel fold Aae Aquifex aeolicus Length = 228 Score = 166 bits (420), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 93/223 (41%), Positives = 129/223 (57%), Gaps = 3/223 (1%) Query: 43 LAATQQRIVAACARVGRDPASVRLLPVSKTKSQAAIRLAYAAGCRMLGENKPQEAWQKWQ 102 L+ +RI AC R GR +LL SKT IR Y G ++ GEN+ QE +K++ Sbjct: 7 LSRVLERIQKACERAGRGENCAKLLGASKTVPPEVIREFYNCGLKVYGENRVQEFLKKYE 66 Query: 103 ALQDLPDLQWSVIGHLQTNKAKLVARFASEFQALDSLRLAEVLERRLQIEGRGLDVLVQV 162 AL+DL DL+W IG LQTNK K + +LD LA+ +++R DVL++V Sbjct: 67 ALKDL-DLEWHFIGRLQTNKVKYLMGKVVLIHSLDRKNLADEIQKRAFKNNIVQDVLIEV 125 Query: 163 NTSGEASKYGLEPDQVAPFLRQLRAFPALRLRGLMTLAVLSAEPERVRPCFARLRQLRER 222 N GE +K G+EP+ + P +++ GLMT+ PE VRP F +LR+LR+ Sbjct: 126 NVGGEETKGGVEPENLKELFEYTLELPNVKVLGLMTIPPYLENPEDVRPYFRKLRELRDE 185 Query: 223 LRQELPDGALLQDLSMGMSGDAEIAIEEGATVVRVGQAIFGAR 265 L++E L LSMGMS D E+AIEEGAT+VR+G +FG R Sbjct: 186 LQREY--NVALPHLSMGMSHDFEVAIEEGATIVRIGTLLFGER 226 >BH2550 [R] COG0325 Predicted enzyme with a TIM-barrel fold Bha Bacillus halodurans Length = 228 Score = 163 bits (412), Expect = 5e-40, Method: Compositional matrix adjust. Identities = 92/225 (40%), Positives = 139/225 (61%), Gaps = 5/225 (2%) Query: 40 RHNLAATQQRIVAACARVGRDPASVRLLPVSKTKSQAAIRLAYAAGCRMLGENKPQEAWQ 99 + L Q+++ AC R GR+P V ++ V+K S+A R A AG +GEN+ + + Sbjct: 4 KDQLKQIQEQMNEACERAGRNPDDVHIIAVTKYVSEARTREALEAGITHIGENRVEGGVE 63 Query: 100 KWQALQDLPDLQWSVIGHLQTNKAK-LVARFASEFQALDSLRLAEVLERRLQIEGRGLDV 158 K +A + + W IG LQ+ K K ++A F +LD L LA+ ++RRL +G+ L+ Sbjct: 64 KRRAFPN--EGTWHFIGSLQSKKVKKMIADF-DYLHSLDRLSLAKEIDRRLP-DGQALNC 119 Query: 159 LVQVNTSGEASKYGLEPDQVAPFLRQLRAFPALRLRGLMTLAVLSAEPERVRPCFARLRQ 218 VQVN SGE SK GL+P++V PF+ +L+ +P++R+ GLMT+A +PE R F LR Sbjct: 120 FVQVNVSGEQSKSGLKPEEVLPFIEELQTYPSIRVVGLMTMAPFVEDPEDTRWVFRELRH 179 Query: 219 LRERLRQELPDGALLQDLSMGMSGDAEIAIEEGATVVRVGQAIFG 263 LR+ ++ + + A +LSMGMS D +AIEEGAT VR+G A+ G Sbjct: 180 LRDEVQAKRFNHAPCSELSMGMSNDFIVAIEEGATFVRIGTALVG 224 >HI0090 [R] COG0325 Predicted enzyme with a TIM-barrel fold Hin Haemophilus influenzae Length = 237 Score = 157 bits (397), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 91/235 (38%), Positives = 133/235 (56%), Gaps = 2/235 (0%) Query: 38 DFRHNLAATQQRIVAACARVGRDPASVRLLPVSKTKSQAAIRLAYAAGCRMLGENKPQEA 97 + +HNL QQ+I AC R+ +V+LL VSKTK +AI AY AG GEN QE Sbjct: 2 NIQHNLNLIQQKIETACKEENRNQNTVKLLAVSKTKPISAILSAYQAGQTAFGENYVQEG 61 Query: 98 WQKWQALQDLP-DLQWSVIGHLQTNKAKLVARFASEFQALDSLRLAEVLERRLQIEGRGL 156 +K Q + +L+W IG LQ+NK +LVA Q LD ++A+ L + L Sbjct: 62 VEKIQYFESQGINLEWHFIGPLQSNKTRLVAEHFDWMQTLDRAKIADRLNEQRPTNKAPL 121 Query: 157 DVLVQVNTSGEASKYGLEPDQVAPFLRQLRAFPALRLRGLMTLAVLSAEPERVRPCFARL 216 +VL+Q+N S E SK G++P+++ + + P L LRGLM + + F ++ Sbjct: 122 NVLIQINISDEESKSGIQPEEMLTLAKHIENLPHLCLRGLMAIPAPTDNIAEQENAFRKM 181 Query: 217 RQLRERLRQELPDGALLQDLSMGMSGDAEIAIEEGATVVRVGQAIFGARDVPDSH 271 +L E+L+Q LP+ + LSMGM+ D AI+ G+T+VR+G AIFGAR+ S Sbjct: 182 LELFEQLKQVLPNQQ-IDTLSMGMTDDMPSAIKCGSTMVRIGTAIFGARNYSTSQ 235 >PM0112 [R] COG0325 Predicted enzyme with a TIM-barrel fold Pmu Pasteurella multocida Length = 233 Score = 155 bits (393), Expect = 8e-38, Method: Compositional matrix adjust. Identities = 95/230 (41%), Positives = 134/230 (58%), Gaps = 4/230 (1%) Query: 39 FRHNLAATQQRIVAACARVGRDPASVRLLPVSKTKSQAAIRLAYAAGCRMLGENKPQEAW 98 NLA QQ I A + R ++V+LL VSKTK I AY AG GEN QE Sbjct: 3 IEQNLAQIQQNIQHAVQQAKRPESAVKLLAVSKTKPVEDIYQAYQAGQTAFGENYVQEGV 62 Query: 99 QKWQ--ALQDLPDLQWSVIGHLQTNKAKLVARFASEFQALDSLRLAEVLERRLQIEGRGL 156 +K Q A +++P L+W IG LQ+NK KLVA Q LD ++A+ L + + L Sbjct: 63 EKIQYFAQKNIP-LEWHFIGPLQSNKTKLVAEHFDWMQTLDRKKIADRLNEQRPHYKKPL 121 Query: 157 DVLVQVNTSGEASKYGLEPDQVAPFLRQLRAFPALRLRGLMTLAVLSAEPERVRPCFARL 216 +VL+Q+N S E SK G++P+++ +Q++ P L LRGLM + + + F ++ Sbjct: 122 NVLIQINISDEDSKSGIQPNEMLDLAKQIQNLPHLCLRGLMAIPAPTDDLATQEQAFTQM 181 Query: 217 RQLRERLRQELPDGALLQDLSMGMSGDAEIAIEEGATVVRVGQAIFGARD 266 L E+L+Q LPD A + LSMGM+ D AI+ G+T+VR+G AIFGARD Sbjct: 182 HSLFEQLKQALPD-AQIDTLSMGMTDDMASAIQCGSTMVRIGTAIFGARD 230