BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0463.p (309 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ZwcaG [MG] COG0451 Nucleoside-diphosphate-sugar epimerases EcZ E... 378 e-104 ECs2857 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Ecs... 378 e-104 wcaG [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Eco Es... 377 e-104 STM2108 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Sty... 372 e-103 CAC2179 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Cac... 370 e-102 >ZwcaG [MG] COG0451 Nucleoside-diphosphate-sugar epimerases EcZ Escherichia coli O157:H7 EDL933 Length = 321 Score = 378 bits (970), Expect = e-104, Method: Compositional matrix adjust. Identities = 183/309 (59%), Positives = 229/309 (74%), Gaps = 9/309 (2%) Query: 6 KIFVAGHRGMVGSAIVRYLNERGYSNVVVRTHAELDLTRQEAVTAFMESEKPDYVFLAAA 65 +IF+AGHRGMVGSAI R L +RG +V+RT EL+L AV F SE+ D V+LAAA Sbjct: 5 RIFIAGHRGMVGSAIRRQLEQRGDVELVLRTRDELNLLDSRAVHDFFASERIDQVYLAAA 64 Query: 66 KVGGINANDTYRAEFLYQNLMMECNVIHAAWQAGVQRMLFLGSSCIYPRDCPQPIREEYL 125 KVGGI AN+TY A+F+YQN+M+E N+IHAA Q V ++LFLGSSCIYP+ QP+ E L Sbjct: 65 KVGGIVANNTYPADFIYQNMMIESNIIHAAHQNDVNKLLFLGSSCIYPKLAKQPMAESEL 124 Query: 126 LTGPLEQTNEPYAIAKIAGVKLCESYNRQYGTQYVAAMPTNLYGPNDNYDLNNSHVLPAL 185 L G LE TNEPYAIAKIAG+KLCESYNRQYG Y + MPTNLYGP+DN+ +NSHV+PAL Sbjct: 125 LQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNLYGPHDNFHPSNSHVIPAL 184 Query: 186 IRKAHEAKLRGDTEYVVWGSGKPMREFLYVDDLAAACVHLMESGVSGGL---------FN 236 +R+ HEA + + VVWGSG PMREFL+VDD+AAA +H+ME L N Sbjct: 185 LRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMAAASIHVMELAHEVWLENTQPMLSHIN 244 Query: 237 IGTGEDITIRELAETVMEVIGFAGKIVFDASKPDGTPRKLLNVDRMKQAGWSAEVTLREG 296 +GTG D TIRELA+T+ +V+G+ G++VFDASKPDGTPRKLL+V R+ Q GW E++L G Sbjct: 245 VGTGVDCTIRELAQTIAKVVGYKGRVVFDASKPDGTPRKLLDVTRLHQLGWYHEISLEAG 304 Query: 297 IRRSYADFL 305 + +Y FL Sbjct: 305 LASTYQWFL 313 >ECs2857 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Ecs Escherichia coli O157:H7 Length = 321 Score = 378 bits (970), Expect = e-104, Method: Compositional matrix adjust. Identities = 183/309 (59%), Positives = 229/309 (74%), Gaps = 9/309 (2%) Query: 6 KIFVAGHRGMVGSAIVRYLNERGYSNVVVRTHAELDLTRQEAVTAFMESEKPDYVFLAAA 65 +IF+AGHRGMVGSAI R L +RG +V+RT EL+L AV F SE+ D V+LAAA Sbjct: 5 RIFIAGHRGMVGSAIRRQLEQRGDVELVLRTRDELNLLDSRAVHDFFASERIDQVYLAAA 64 Query: 66 KVGGINANDTYRAEFLYQNLMMECNVIHAAWQAGVQRMLFLGSSCIYPRDCPQPIREEYL 125 KVGGI AN+TY A+F+YQN+M+E N+IHAA Q V ++LFLGSSCIYP+ QP+ E L Sbjct: 65 KVGGIVANNTYPADFIYQNMMIESNIIHAAHQNDVNKLLFLGSSCIYPKLAKQPMAESEL 124 Query: 126 LTGPLEQTNEPYAIAKIAGVKLCESYNRQYGTQYVAAMPTNLYGPNDNYDLNNSHVLPAL 185 L G LE TNEPYAIAKIAG+KLCESYNRQYG Y + MPTNLYGP+DN+ +NSHV+PAL Sbjct: 125 LQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNLYGPHDNFHPSNSHVIPAL 184 Query: 186 IRKAHEAKLRGDTEYVVWGSGKPMREFLYVDDLAAACVHLMESGVSGGL---------FN 236 +R+ HEA + + VVWGSG PMREFL+VDD+AAA +H+ME L N Sbjct: 185 LRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMAAASIHVMELAHEVWLENTQPMLSHIN 244 Query: 237 IGTGEDITIRELAETVMEVIGFAGKIVFDASKPDGTPRKLLNVDRMKQAGWSAEVTLREG 296 +GTG D TIRELA+T+ +V+G+ G++VFDASKPDGTPRKLL+V R+ Q GW E++L G Sbjct: 245 VGTGVDCTIRELAQTIAKVVGYKGRVVFDASKPDGTPRKLLDVTRLHQLGWYHEISLEAG 304 Query: 297 IRRSYADFL 305 + +Y FL Sbjct: 305 LASTYQWFL 313 >wcaG [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Eco Escherichia coli K12 Length = 321 Score = 377 bits (968), Expect = e-104, Method: Compositional matrix adjust. Identities = 182/309 (58%), Positives = 229/309 (74%), Gaps = 9/309 (2%) Query: 6 KIFVAGHRGMVGSAIVRYLNERGYSNVVVRTHAELDLTRQEAVTAFMESEKPDYVFLAAA 65 ++F+AGHRGMVGSAI R L +RG +V+RT EL+L AV F SE+ D V+LAAA Sbjct: 5 RVFIAGHRGMVGSAIRRQLEQRGDVELVLRTRDELNLLDSRAVHDFFASERIDQVYLAAA 64 Query: 66 KVGGINANDTYRAEFLYQNLMMECNVIHAAWQAGVQRMLFLGSSCIYPRDCPQPIREEYL 125 KVGGI AN+TY A+F+YQN+M+E N+IHAA Q V ++LFLGSSCIYP+ QP+ E L Sbjct: 65 KVGGIVANNTYPADFIYQNMMIESNIIHAAHQNDVNKLLFLGSSCIYPKLAKQPMAESEL 124 Query: 126 LTGPLEQTNEPYAIAKIAGVKLCESYNRQYGTQYVAAMPTNLYGPNDNYDLNNSHVLPAL 185 L G LE TNEPYAIAKIAG+KLCESYNRQYG Y + MPTNLYGP+DN+ +NSHV+PAL Sbjct: 125 LQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNLYGPHDNFHPSNSHVIPAL 184 Query: 186 IRKAHEAKLRGDTEYVVWGSGKPMREFLYVDDLAAACVHLMESGVSGGL---------FN 236 +R+ HEA + + VVWGSG PMREFL+VDD+AAA +H+ME L N Sbjct: 185 LRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMAAASIHVMELAHEVWLENTQPMLSHIN 244 Query: 237 IGTGEDITIRELAETVMEVIGFAGKIVFDASKPDGTPRKLLNVDRMKQAGWSAEVTLREG 296 +GTG D TIRELA+T+ +V+G+ G++VFDASKPDGTPRKLL+V R+ Q GW E++L G Sbjct: 245 VGTGVDCTIRELAQTIAKVVGYKGRVVFDASKPDGTPRKLLDVTRLHQLGWYHEISLEAG 304 Query: 297 IRRSYADFL 305 + +Y FL Sbjct: 305 LASTYQWFL 313 >STM2108 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Sty Salmonella typhimurium LT2 Length = 321 Score = 372 bits (954), Expect = e-103, Method: Compositional matrix adjust. Identities = 185/314 (58%), Positives = 229/314 (72%), Gaps = 10/314 (3%) Query: 1 MNKDAKIFVAGHRGMVGSAIVRYLNERGYSNVVVRTHAELDLTRQEAVTAFMESEKPDYV 60 MNK +IFVAGHRGMVGSAIVR L +RG +V+RT ELDL AV AF D V Sbjct: 1 MNKQ-RIFVAGHRGMVGSAIVRQLAQRGDVELVLRTRDELDLLDGRAVQAFFAGAGIDQV 59 Query: 61 FLAAAKVGGINANDTYRAEFLYQNLMMECNVIHAAWQAGVQRMLFLGSSCIYPRDCPQPI 120 +LAAAKVGGI AN+TY A+F+Y+N+M+E N+IHAA V ++LFLGSSCIYP+ QP+ Sbjct: 60 YLAAAKVGGIVANNTYPADFIYENMMIESNIIHAAHLHNVNKLLFLGSSCIYPKLARQPM 119 Query: 121 REEYLLTGPLEQTNEPYAIAKIAGVKLCESYNRQYGTQYVAAMPTNLYGPNDNYDLNNSH 180 E LL G LE TNEPYAIAKIAG+KLCESYNRQYG Y + MPTNLYGP+DN+ +NSH Sbjct: 120 AESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNLYGPHDNFHPDNSH 179 Query: 181 VLPALIRKAHEAKLRGDTEYVVWGSGKPMREFLYVDDLAAACVHLME---------SGVS 231 V+PAL+R+ HEA E VVWGSG PMREFL+VDD+AAA +H+ME + Sbjct: 180 VIPALLRRFHEAAQSHAPEVVVWGSGTPMREFLHVDDMAAASIHVMELAREVWQENTAPM 239 Query: 232 GGLFNIGTGEDITIRELAETVMEVIGFAGKIVFDASKPDGTPRKLLNVDRMKQAGWSAEV 291 N+GTG D TIRELA+T+ +V+G+ G++VFDA+KPDGTPRKLL+V R+ Q GW E+ Sbjct: 240 LSHINVGTGVDCTIRELAQTIAKVVGYQGRVVFDAAKPDGTPRKLLDVTRLHQLGWYHEI 299 Query: 292 TLREGIRRSYADFL 305 +L G+ +Y FL Sbjct: 300 SLEAGLAGTYQWFL 313 >CAC2179 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Cac Clostridium acetobutylicum Length = 309 Score = 370 bits (950), Expect = e-102, Method: Compositional matrix adjust. Identities = 171/307 (55%), Positives = 228/307 (74%), Gaps = 1/307 (0%) Query: 1 MNKDAKIFVAGHRGMVGSAIVRYLNERGYSNVVVRTHAELDLTRQEAVTAFMESEKPDYV 60 M +D+KI++AGH G VGSAI+R L RGY NVVVRTH ELDL QE+V F+E EKPDYV Sbjct: 1 MKEDSKIYIAGHTGFVGSAILRNLERRGYKNVVVRTHKELDLMHQESVKKFLEEEKPDYV 60 Query: 61 FLAAAKVGGINANDTYRAEFLYQNLMMECNVIHAAWQAGVQRMLFLGSSCIYPRDCPQPI 120 L+AAKVGGI AN + +FL NL++E NVI +++ G++ +LFLGSSCIYP++ PQP+ Sbjct: 61 VLSAAKVGGIQANISNPVDFLMDNLIIEYNVIKNSFEVGIENLLFLGSSCIYPKEAPQPL 120 Query: 121 REEYLLTGPLEQTNEPYAIAKIAGVKLCESYNRQYGTQYVAAMPTNLYGPNDNYDLNNSH 180 +EEYLL+G LE TNE YAIAKI+G+K+CE Y++QYG Y++AMP+NLYG DN+DL SH Sbjct: 121 KEEYLLSGYLEPTNEGYAIAKISGLKMCEYYSKQYGLNYISAMPSNLYGMRDNFDLKTSH 180 Query: 181 VLPALIRKAHEAKLRGDTEYVVWGSGKPMREFLYVDDLAAACVHLMESGVS-GGLFNIGT 239 V+ ALIR+ HEAK+ G E +WGSG+ REF Y++DLA + LME G G NIG Sbjct: 181 VMAALIRRFHEAKVSGSQEISIWGSGEQYREFTYIEDLADGIIFLMEHGEKVKGFLNIGC 240 Query: 240 GEDITIRELAETVMEVIGFAGKIVFDASKPDGTPRKLLNVDRMKQAGWSAEVTLREGIRR 299 G+DI I++LA + +V+GF G I+FD SKPDG RK+++V ++ GW +V L EGI + Sbjct: 241 GKDIKIKDLAYKIKDVVGFKGNIIFDKSKPDGMFRKVMDVSKINSLGWHYKVELDEGITK 300 Query: 300 SYADFLS 306 +Y +L+ Sbjct: 301 TYRWYLN 307