BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0411.p (269 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0381 [H] COG2022 Uncharacterized enzyme of thiazole biosynthes... 368 e-102 XF0783 [H] COG2022 Uncharacterized enzyme of thiazole biosynthes... 348 8e-96 CC1880 Non COG 324 1e-88 aq_2178 [H] COG2022 Uncharacterized enzyme of thiazole biosynthe... 290 2e-78 BS_yjbT [H] COG2022 Uncharacterized enzyme of thiazole biosynthe... 253 3e-67 >PA0381 [H] COG2022 Uncharacterized enzyme of thiazole biosynthesis Pae Pseudomonas aeruginosa Length = 265 Score = 368 bits (944), Expect = e-102, Method: Compositional matrix adjust. Identities = 182/257 (70%), Positives = 214/257 (83%) Query: 12 DQGLTIAGKTYRSRLLVGSGKYKDLDETRAATVASGAEIITVAIRRVNIGQDPNAPSLLD 71 D IAG+TY SRLLVG+GKYKDLDETR A ASGAEI+TVA+RR NIGQ+P+ P+LLD Sbjct: 8 DTPFVIAGRTYGSRLLVGTGKYKDLDETRRAIEASGAEIVTVAVRRTNIGQNPDEPNLLD 67 Query: 72 AVPPSEFTILPNTAGCYNAADAVYTLQLARELLGGHKLVKLEVLGDEKTLFPNMPETLKA 131 +PP +TILPNTAGCY+A +AV T +LARELL GH LVKLEVL D+KTLFPN+ ETLKA Sbjct: 68 VIPPDRYTILPNTAGCYDAVEAVRTCRLARELLDGHNLVKLEVLADQKTLFPNVVETLKA 127 Query: 132 ADILVKDGFDVMVYCSDDPIQARMLEDLGVAAVMPLASLIGSGMGILNPWNLSLIIDQAR 191 A+ LVKDGFDVMVY SDDPI AR L ++G AVMPLA LIGSG+GI NP+NL +I+++A+ Sbjct: 128 AEQLVKDGFDVMVYTSDDPIIARQLAEIGCIAVMPLAGLIGSGLGICNPYNLRIILEEAK 187 Query: 192 VPVLVDAGVGTASDAAIAMELGCDGVLMNTAIAGARDPIRMARAMKLAVDAGREAFLAGR 251 VPVLVDAGVGTASDAAIAMELGC+ VLMNTAIA A+DP+ MA AMK A+ AGR A+LAGR Sbjct: 188 VPVLVDAGVGTASDAAIAMELGCEAVLMNTAIAHAKDPVMMAEAMKHAIVAGRLAYLAGR 247 Query: 252 IARKFAASPSSPMAGRV 268 + RK AS SSP+ G + Sbjct: 248 MPRKLYASASSPLDGLI 264 >XF0783 [H] COG2022 Uncharacterized enzyme of thiazole biosynthesis Xfa Xylella fastidiosa 9a5c Length = 275 Score = 348 bits (893), Expect = 8e-96, Method: Compositional matrix adjust. Identities = 174/254 (68%), Positives = 210/254 (82%) Query: 15 LTIAGKTYRSRLLVGSGKYKDLDETRAATVASGAEIITVAIRRVNIGQDPNAPSLLDAVP 74 L IAG Y SRLL G+GK+KDLDETR AT A+G++I+TVAIRRVNIGQDP+ P+LL+ + Sbjct: 21 LVIAGIVYSSRLLTGTGKFKDLDETRLATEAAGSQIVTVAIRRVNIGQDPHQPNLLNVLS 80 Query: 75 PSEFTILPNTAGCYNAADAVYTLQLARELLGGHKLVKLEVLGDEKTLFPNMPETLKAADI 134 P +TILPNTAGCY A DAV T +LARELL GH+L KLEVLGD+KTL+P++ +TLKAA+ Sbjct: 81 PDRYTILPNTAGCYTAEDAVRTCRLARELLDGHRLTKLEVLGDKKTLYPDVVQTLKAAEQ 140 Query: 135 LVKDGFDVMVYCSDDPIQARMLEDLGVAAVMPLASLIGSGMGILNPWNLSLIIDQARVPV 194 LV + F VMVY SDDPI A+ LE++G AVMPLA+ IGSG+G+ N +NL II+ A+VP+ Sbjct: 141 LVAEDFQVMVYTSDDPILAKRLEEIGCVAVMPLAAPIGSGLGVQNRYNLLEIIENAQVPI 200 Query: 195 LVDAGVGTASDAAIAMELGCDGVLMNTAIAGARDPIRMARAMKLAVDAGREAFLAGRIAR 254 +VDAGVGTASDAAIAMELGCD VLMNTAIAGARDP+ MA AM+ AV+AGREAFLAGRI R Sbjct: 201 IVDAGVGTASDAAIAMELGCDAVLMNTAIAGARDPVLMASAMRKAVEAGREAFLAGRIPR 260 Query: 255 KFAASPSSPMAGRV 268 K A+ SSP+ G V Sbjct: 261 KRYAAASSPVEGLV 274 >CC1880 Non COG Length = 269 Score = 324 bits (831), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 171/270 (63%), Positives = 210/270 (77%), Gaps = 8/270 (2%) Query: 5 DAHLTRE------DQGLTIAGKTYRSRLLVGSGKYKDLDETRAATVASGAEIITVAIRRV 58 +AH+T + D+ T+AG+T+RSRL+VG+GKYKD AA A+GAEI+TVA+RRV Sbjct: 2 NAHVTPDSVTADSDETWTVAGRTFRSRLIVGTGKYKDYATNAAAARAAGAEIVTVAVRRV 61 Query: 59 NIGQDPNAPSLLDAVPPSEFTILPNTAGCYNAADAVYTLQLARELLGGHKLVKLEVLGDE 118 N+ DP+ P L+D V P+EFT LPNTAGC+ DAV TL+LARE GG LVKLEVL D Sbjct: 62 NL-TDPSQPLLVDYVKPTEFTYLPNTAGCFTGEDAVRTLRLAREA-GGWDLVKLEVLSDP 119 Query: 119 KTLFPNMPETLKAADILVKDGFDVMVYCSDDPIQARMLEDLGVAAVMPLASLIGSGMGIL 178 KTLFP+M ETL++ +LV DGF VMVYCSDDP+ AR LE+ G A+MPL + IGSG+GI Sbjct: 120 KTLFPDMEETLRSLKLLVADGFQVMVYCSDDPVYARKLEEAGAVAIMPLGAPIGSGLGIQ 179 Query: 179 NPWNLSLIIDQARVPVLVDAGVGTASDAAIAMELGCDGVLMNTAIAGARDPIRMARAMKL 238 N NL +II+ A+VPVLVDAGVGTASDAAI MELGCD +LMNTAIA A+DPIRMA+AMK Sbjct: 180 NRVNLRIIIENAKVPVLVDAGVGTASDAAIGMELGCDAILMNTAIAEAKDPIRMAKAMKH 239 Query: 239 AVDAGREAFLAGRIARKFAASPSSPMAGRV 268 AV AGREA+LAGR+ ++ A PSSP+AG + Sbjct: 240 AVIAGREAYLAGRMQKRLYADPSSPLAGLI 269 >aq_2178 [H] COG2022 Uncharacterized enzyme of thiazole biosynthesis Aae Aquifex aeolicus Length = 267 Score = 290 bits (743), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 148/264 (56%), Positives = 191/264 (72%), Gaps = 2/264 (0%) Query: 3 MNDAHLTREDQGLTIAGKTYRSRLLVGSGKYKDLDETRAATVASGAEIITVAIRRVNIGQ 62 M D +D L IAG+ ++SRL++GSGK+KD +T+ ASGAEIITVA+RRVNI Sbjct: 1 MQDWEKLLQDDYLEIAGRKFKSRLIIGSGKFKDFQQTKEVLEASGAEIITVAVRRVNI-T 59 Query: 63 DPNAPSLLDAVPPSEFTILPNTAGCYNAADAVYTLQLARELLGGHKLVKLEVLGDEKTLF 122 DP +LLD + P ++ ILPNTAGCY A +A+ T +ARE G + VKLEV+GD+KTL Sbjct: 60 DPTKENLLDYIDPKKYLILPNTAGCYTAEEAIKTAMMAREATGIN-WVKLEVIGDQKTLL 118 Query: 123 PNMPETLKAADILVKDGFDVMVYCSDDPIQARMLEDLGVAAVMPLASLIGSGMGILNPWN 182 P+M ET KAA +LVK+GF V+ Y DDP+ A+ ED+G AAVMPLA+ IGSG+G+ NP+N Sbjct: 119 PDMEETYKAAKVLVKEGFVVLPYIFDDPVFAKKFEDIGCAAVMPLAAPIGSGLGLQNPYN 178 Query: 183 LSLIIDQARVPVLVDAGVGTASDAAIAMELGCDGVLMNTAIAGARDPIRMARAMKLAVDA 242 L I + VPV+VDAG+G+A+D MELG DGVL NTA+A A+DPI+MA AMK A A Sbjct: 179 LIFIKEAVSVPVIVDAGIGSATDIPPVMELGVDGVLTNTALAEAKDPIKMAVAMKYATIA 238 Query: 243 GREAFLAGRIARKFAASPSSPMAG 266 GR A+LAGR+ ++ A PSSP G Sbjct: 239 GRLAYLAGRMPKRTYAVPSSPTKG 262 >BS_yjbT [H] COG2022 Uncharacterized enzyme of thiazole biosynthesis Bsu Bacillus subtilis Length = 256 Score = 253 bits (647), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 134/252 (53%), Positives = 186/252 (73%), Gaps = 2/252 (0%) Query: 15 LTIAGKTYRSRLLVGSGKYKDLDETRAATVASGAEIITVAIRRVNIGQDPNAPSLLDAVP 74 LTI GK+++SRLL+G+GKY D + A S ++I+T A+RR+NI + + P+ L+ + Sbjct: 4 LTIGGKSFQSRLLLGTGKYPSFDIQKEAVAVSESDILTFAVRRMNIFE-ASQPNFLEQLD 62 Query: 75 PSEFTILPNTAGCYNAADAVYTLQLARELLGGHKLVKLEVLGDEKTLFPNMPETLKAADI 134 S++T+LPNTAG A +AV +LA+ G ++K+EV+G ++L P+ ETLKA++ Sbjct: 63 LSKYTLLPNTAGASTAEEAVRIARLAKAS-GLCDMIKVEVIGCSRSLLPDPVETLKASEQ 121 Query: 135 LVKDGFDVMVYCSDDPIQARMLEDLGVAAVMPLASLIGSGMGILNPWNLSLIIDQARVPV 194 L+++GF V+ Y SDD + AR LE+LGV A+MP AS IGSG GILNP NLS II+QA+VPV Sbjct: 122 LLEEGFIVLPYTSDDVVLARKLEELGVHAIMPGASPIGSGQGILNPLNLSFIIEQAKVPV 181 Query: 195 LVDAGVGTASDAAIAMELGCDGVLMNTAIAGARDPIRMARAMKLAVDAGREAFLAGRIAR 254 +VDAG+G+ DAA AMELG DGVL+NTA++GA DP++MARAMKLAV+AGR ++ AGRI Sbjct: 182 IVDAGIGSPKDAAYAMELGADGVLLNTAVSGADDPVKMARAMKLAVEAGRLSYEAGRIPL 241 Query: 255 KFAASPSSPMAG 266 K + SSP G Sbjct: 242 KQYGTASSPGEG 253