BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0331.p (429 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2824 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB Rso ... 483 e-136 VC0558 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB Vch V... 320 3e-87 YPO3298 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB Ype ... 315 2e-85 STM2679 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB Sty ... 308 1e-83 yfjDm [P] COG4536 Putative Mg2+ and Co2+ transporter CorB Eco Es... 306 7e-83 >RSc2824 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB Rso Ralstonia solanacearum Length = 425 Score = 483 bits (1243), Expect = e-136, Method: Compositional matrix adjust. Identities = 237/419 (56%), Positives = 317/419 (75%), Gaps = 4/419 (0%) Query: 1 LDTVPIWVQALALLILILLSAFFSMTETALMAANRHRLRHLAKQGNRAAITILWLLDRTE 60 +D+ P+W Q A+++L+ SAFFS++ET+LMA NRHRLRHLAK A LL +T+ Sbjct: 1 MDSWPLWAQLGAVVLLLCCSAFFSISETSLMALNRHRLRHLAKSNVAGARRTQGLLGQTD 60 Query: 61 RLLSLILIANTVINALATALVTALAIAAFGNHQRVITAATAFVAALLIVFAEIVPKVIGA 120 +LLSLILI N +IN L+ LAI FGN ++ ATA VA L+IVF EI PK+ GA Sbjct: 61 KLLSLILIGNNLINTAVPVLIANLAIHYFGNSGTTLSIATAIVAFLIIVFCEIAPKIAGA 120 Query: 121 THPERIALFTSFILKPLMRVAKPLVWFVNIFVSAILKLLHIKTGARAAEQRISPEELRSI 180 T+PERI+ SFI+ PL+R+A PLV VN FV+ +L+L+ I +A EQR+S EELR++ Sbjct: 121 TYPERISFPASFIIAPLLRLATPLVTVVNAFVTVLLRLVRINP-RQAPEQRMSAEELRTL 179 Query: 181 VLEGGSFIPQKHKSILLNLFDLEKISVEDVMTPRAQVEALNLAAPVEDILHQLATCYHNK 240 VLE G+FIP KH+SILLNLFDL+ I+V+DVMTPRA+VE+L+L+ P+E+++ QL TCYHNK Sbjct: 180 VLESGNFIPHKHRSILLNLFDLDAITVDDVMTPRARVESLDLSRPIEEVIQQLETCYHNK 239 Query: 241 LPVFEGEINHIVGILHVRKTVSLFRQEEEISHDDIRALLSAPYYVPVETDIFTQLQYFQE 300 LPVFE + + ++GILHVRK +SL E I HDD R+LL+ PY+VP T +F QLQYFQE Sbjct: 240 LPVFEQDTDQVLGILHVRKALSLLGHAELI-HDDFRSLLAKPYFVPSGTPVFRQLQYFQE 298 Query: 301 NHERLGIVVDEYGEVQGLVTLEDIIEEMIGEFTTSSPGSSGEGFNWDKEGTCLLEGSTTL 360 N R+G+V++EYG++ GLVTLEDIIEEMIGEFTT+ P + WD + L + +L Sbjct: 299 NRRRIGLVINEYGDMLGLVTLEDIIEEMIGEFTTTLPNAG--KLAWDAQNAYLADAGMSL 356 Query: 361 RDINKRLGLKLPLDGPKTINGLLLETLQDIPEASVAVKIDGCVIEIVQVQNQAIRMVKL 419 RD+N+RLGL+LP DGPKT+NGL+LE L++IPEA V+V+I GCV++IVQ+ +Q+IR V+L Sbjct: 357 RDLNRRLGLQLPTDGPKTLNGLVLEVLEEIPEAPVSVRIAGCVMDIVQMDSQSIRTVRL 415 >VC0558 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB Vch Vibrio cholerae Length = 426 Score = 320 bits (821), Expect = 3e-87, Method: Compositional matrix adjust. Identities = 160/419 (38%), Positives = 269/419 (64%), Gaps = 3/419 (0%) Query: 1 LDTVPIWVQALALLILILLSAFFSMTETALMAANRHRLRHLAKQGNRAAITILWLLDRTE 60 +D + + L LI++SA+FS +ET +MA NR+RL+HLA G++ A + LLDR + Sbjct: 1 MDDISTGILFALLACLIIISAYFSGSETGMMALNRYRLKHLANSGHKGAKRVEKLLDRPD 60 Query: 61 RLLSLILIANTVINALATALVTALAIAAFGNHQRVITAATAFVAALLIVFAEIVPKVIGA 120 RL+ LILI N ++N LA+A+ T + + +G+ + AT + +++VFAE+ PK + A Sbjct: 61 RLIGLILIGNNLVNILASAIATIIGMRLYGDLG--VAIATGALTLVILVFAEVTPKTLAA 118 Query: 121 THPERIALFTSFILKPLMRVAKPLVWFVNIFVSAILKLLHIKTGARAAEQRISPEELRSI 180 +PER++ +S +L LM++ PLV FVN+ + ++++L I + +S EELR++ Sbjct: 119 LYPERVSYASSVLLTILMKLLSPLVLFVNLMTNGLIRILGI-SPKHGKGDHLSSEELRTV 177 Query: 181 VLEGGSFIPQKHKSILLNLFDLEKISVEDVMTPRAQVEALNLAAPVEDILHQLATCYHNK 240 V E G IP++H+ +LL++ DLE ++V D+M PR ++ +N+ + I+ QL H + Sbjct: 178 VNEAGGLIPRRHQDMLLSILDLEHVTVNDIMIPRNEITGININDDWKSIVRQLVHSPHGR 237 Query: 241 LPVFEGEINHIVGILHVRKTVSLFRQEEEISHDDIRALLSAPYYVPVETDIFTQLQYFQE 300 + ++ +I+ +VGIL +R+ ++ + + + + Y++P T + QL FQ Sbjct: 238 VVLYRDKIDEVVGILRLREASRFMLEKNDFNKEMLLRAADEIYFIPEGTPLNVQLLKFQR 297 Query: 301 NHERLGIVVDEYGEVQGLVTLEDIIEEMIGEFTTSSPGSSGEGFNWDKEGTCLLEGSTTL 360 N ER+G++VDEYGE+ GL TLEDI+EE++GEFTTS S + +G+ L+EGS + Sbjct: 298 NKERIGLIVDEYGEIIGLTTLEDILEEIVGEFTTSMSPSLADEITPQGDGSFLIEGSANI 357 Query: 361 RDINKRLGLKLPLDGPKTINGLLLETLQDIPEASVAVKIDGCVIEIVQVQNQAIRMVKL 419 RDINK L KLP DGP+T+NGL+LE L++IP + ++VK+ +EI++++ I++VK+ Sbjct: 358 RDINKSLKWKLPTDGPRTLNGLILEHLEEIPASHLSVKVAQHKMEILELEENRIKLVKV 416 >YPO3298 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB Ype Yersinia pestis Length = 427 Score = 315 bits (806), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 152/400 (38%), Positives = 263/400 (65%), Gaps = 4/400 (1%) Query: 20 SAFFSMTETALMAANRHRLRHLAKQGNRAAITILWLLDRTERLLSLILIANTVINALATA 79 SA+FS +ET +M NR+R+RHL+KQGNRAA + LL+R +RL+SL+LI N ++N LA+A Sbjct: 21 SAYFSASETGMMTLNRYRMRHLSKQGNRAARRVEKLLNRPDRLISLVLIGNNLVNILASA 80 Query: 80 LVTALAIAAFGNHQRVITAATAFVAALLIVFAEIVPKVIGATHPERIALFTSFILKPLMR 139 L T + I +G+ + AT + ++++FAE++PK I A +PER+A +S +L PL + Sbjct: 81 LATIVGIRLYGDAG--VAIATGVLTFVILIFAEVLPKTIAALYPERVAFPSSMLLAPLQK 138 Query: 140 VAKPLVWFVNIFVSAILKLLHIKTGARAAEQRISPEELRSIVLEGGSFIPQKHKSILLNL 199 + PLVW +N ++ L I+ +++ +S +ELR+IV E S I ++++ +L+++ Sbjct: 139 IMLPLVWLLNTITRGLMHLCGIRGNVHSSDA-MSKDELRTIVSESQSKISRRNQDMLISV 197 Query: 200 FDLEKISVEDVMTPRAQVEALNLAAPVEDILHQLATCYHNKLPVFEGEINHIVGILHVRK 259 DLEK++V D+M PR +V +++ + I+ QL H ++ ++ ++ +G+L VR+ Sbjct: 198 LDLEKVTVSDIMVPRNEVVGIDINDDWKSIMRQLTHSPHGRIVLYRQSLDDAIGMLRVRE 257 Query: 260 TVSLFRQEEEISHDDIRALLSAPYYVPVETDIFTQLQYFQENHERLGIVVDEYGEVQGLV 319 L +++E + +++ Y++P T + QL FQ N +++G++VDEYG++QGLV Sbjct: 258 AYRLMTEKKEFNKENLLRAADEIYFIPEGTPLNVQLVKFQRNKKKVGMIVDEYGDIQGLV 317 Query: 320 TLEDIIEEMIGEFTTSSPGSSGEGFNWDKEGTCLLEGSTTLRDINKRLGLKLPLDGPKTI 379 T+EDI+EE++G+FTTS + E N +G+ L++GS ++R++NK LP+D +TI Sbjct: 318 TVEDILEEIVGDFTTSMSPTLAEEVNPQSDGSVLIDGSASVREVNKAFNWSLPVDA-RTI 376 Query: 380 NGLLLETLQDIPEASVAVKIDGCVIEIVQVQNQAIRMVKL 419 NG+LLE L++IP+A + V++ IE++ VQ I+ VK+ Sbjct: 377 NGMLLEELEEIPQAHIHVRLGNYQIEVLDVQENMIKRVKI 416 >STM2679 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB Sty Salmonella typhimurium LT2 Length = 413 Score = 308 bits (789), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 155/409 (37%), Positives = 264/409 (64%), Gaps = 3/409 (0%) Query: 16 LILLSAFFSMTETALMAANRHRLRHLAKQGNRAAITILWLLDRTERLLSLILIANTVINA 75 ++++SA+FS +ET +M NR+RLRH+AKQGNR+A + LL + +RL+SL+LI N ++N Sbjct: 1 MVVISAYFSGSETGMMTLNRYRLRHMAKQGNRSAKRVEKLLRKPDRLISLVLIGNNLVNI 60 Query: 76 LATALVTALAIAAFGNHQRVITAATAFVAALLIVFAEIVPKVIGATHPERIALFTSFILK 135 LA+AL T + + +G+ + AT + +++VFAE++PK I A +PE++A +SF+L Sbjct: 61 LASALGTIVGMRLYGDAG--VAIATGVLTFVVLVFAEVLPKTIAALYPEKVAYPSSFLLA 118 Query: 136 PLMRVAKPLVWFVNIFVSAILKLLHIKTGARAAEQRISPEELRSIVLEGGSFIPQKHKSI 195 PL + PLVW +N +++L+ IKT +S EELR+IV E S I ++++ + Sbjct: 119 PLQILMMPLVWLLNTITRLLMRLMGIKTDI-VVSGSLSKEELRTIVHESRSQISRRNQDM 177 Query: 196 LLNLFDLEKISVEDVMTPRAQVEALNLAAPVEDILHQLATCYHNKLPVFEGEINHIVGIL 255 LL++ DLEK+SV+D+M PR ++ +++ + I QL H ++ ++ ++ + +L Sbjct: 178 LLSVLDLEKVSVDDIMVPRNEIIGIDINDDWKSIERQLTHSPHGRIVLYRDSLDDAISML 237 Query: 256 HVRKTVSLFRQEEEISHDDIRALLSAPYYVPVETDIFTQLQYFQENHERLGIVVDEYGEV 315 VR+ L +++E + + + YYVP T + TQL FQ N +++G+VV+EYG++ Sbjct: 238 RVREAWRLMAEKKEFTKEMMLRAADEIYYVPEGTPLSTQLIKFQRNKKKVGLVVNEYGDI 297 Query: 316 QGLVTLEDIIEEMIGEFTTSSPGSSGEGFNWDKEGTCLLEGSTTLRDINKRLGLKLPLDG 375 QGLVT+EDI+EE++G+FTTS + E +G+ +++G+ +R+INK LP D Sbjct: 298 QGLVTVEDILEEIVGDFTTSMSPTLAEEVTPQNDGSVIIDGTANVREINKAFNWHLPEDD 357 Query: 376 PKTINGLLLETLQDIPEASVAVKIDGCVIEIVQVQNQAIRMVKLIALPP 424 +T+NG++LE L++IP A V+I+ I+I+ VQ I+ VK++ + P Sbjct: 358 ARTVNGVILEALEEIPVAGTRVRIEQYDIDILDVQENMIKQVKVVPVKP 406 >yfjDm [P] COG4536 Putative Mg2+ and Co2+ transporter CorB Eco Escherichia coli K12 Length = 420 Score = 306 bits (784), Expect = 7e-83, Method: Compositional matrix adjust. Identities = 153/405 (37%), Positives = 262/405 (64%), Gaps = 3/405 (0%) Query: 20 SAFFSMTETALMAANRHRLRHLAKQGNRAAITILWLLDRTERLLSLILIANTVINALATA 79 SA+FS +ET +M NR+RLRH+AKQGNR+A + LL + +RL+SL+LI N ++N LA+A Sbjct: 12 SAYFSGSETGMMTLNRYRLRHMAKQGNRSAKRVEKLLRKPDRLISLVLIGNNLVNILASA 71 Query: 80 LVTALAIAAFGNHQRVITAATAFVAALLIVFAEIVPKVIGATHPERIALFTSFILKPLMR 139 L T + + +G+ + AT + +++VFAE++PK I A +PE++A +SF+L PL Sbjct: 72 LGTIVGMRLYGDAG--VAIATGVLTFVVLVFAEVLPKTIAALYPEKVAYPSSFLLAPLQI 129 Query: 140 VAKPLVWFVNIFVSAILKLLHIKTGARAAEQRISPEELRSIVLEGGSFIPQKHKSILLNL 199 + PLVW +N +++++ IKT +S EELR+IV E S I ++++ +LL++ Sbjct: 130 LMMPLVWLLNAITRMLMRMMGIKTDI-VVSGSLSKEELRTIVHESRSQISRRNQDMLLSV 188 Query: 200 FDLEKISVEDVMTPRAQVEALNLAAPVEDILHQLATCYHNKLPVFEGEINHIVGILHVRK 259 DLEK++V+D+M PR+++ +++ + IL QL+ H ++ ++ ++ + +L VR+ Sbjct: 189 LDLEKMTVDDIMVPRSEIIGIDINDDWKSILRQLSHSPHGRIVLYRDSLDDAISMLRVRE 248 Query: 260 TVSLFRQEEEISHDDIRALLSAPYYVPVETDIFTQLQYFQENHERLGIVVDEYGEVQGLV 319 L +++E + + + Y+VP T + TQL FQ N +++G+VV+EYG++QGLV Sbjct: 249 AWRLMSEKKEFTKETMLRAADEIYFVPEGTPLSTQLVKFQRNKKKVGLVVNEYGDIQGLV 308 Query: 320 TLEDIIEEMIGEFTTSSPGSSGEGFNWDKEGTCLLEGSTTLRDINKRLGLKLPLDGPKTI 379 T+EDI+EE++G+FTTS + E +G+ +++G+ +R+INK LP D +T+ Sbjct: 309 TVEDILEEIVGDFTTSMSPTLAEEVTPQNDGSVIIDGTANVREINKAFNWHLPEDDARTV 368 Query: 380 NGLLLETLQDIPEASVAVKIDGCVIEIVQVQNQAIRMVKLIALPP 424 NG++LE L++IP A V+I I+I+ VQ+ I+ VK+ + P Sbjct: 369 NGVILEALEEIPVAGTRVRIGEYDIDILDVQDNMIKQVKVFPVKP 413