BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0328.p (287 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VC2426 [NOU] COG1989 Type II secretory pathway, prepilin signal ... 252 6e-67 NMB0332 [NOU] COG1989 Type II secretory pathway, prepilin signal... 244 1e-64 NMA2156 [NOU] COG1989 Type II secretory pathway, prepilin signal... 240 3e-63 RSc2827 [NOU] COG1989 Type II secretory pathway, prepilin signal... 228 2e-59 YPO0806 [NOU] COG1989 Type II secretory pathway, prepilin signal... 205 8e-53 >VC2426 [NOU] COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Vch Vibrio cholerae Length = 291 Score = 252 bits (644), Expect = 6e-67, Method: Compositional matrix adjust. Identities = 140/268 (52%), Positives = 179/268 (66%), Gaps = 6/268 (2%) Query: 18 VAALLGLLVGSFLNVVIHRLPAMMLRESANFVAHERGE--ALPHTERYNLWLPHSACPHC 75 +A L GL+VGSFLNVVI+RLP +M RE A E P + L LP S CPHC Sbjct: 14 LATLFGLIVGSFLNVVIYRLPKIMEREWRAECAASFPEYGITPPEGKLTLSLPRSTCPHC 73 Query: 76 ATPLALHHKLPVLSWLLLRGRCAYCSAPISLRYPLVELLCAVLFALLAWRYGLGLTGLAL 135 TP+ + +P+LSWL LRG+C++C APIS RYPL+ELL A++ ++A + G+ +AL Sbjct: 74 QTPIRVIDNIPLLSWLALRGQCSHCKAPISARYPLIELLTALMSLVIATHFPFGVFAVAL 133 Query: 136 MTGAAFLVALAFIDAQTMLLPDDLTLPLLWLGL-LVNLTHRLVPLQDAVLGAMAGYGVLW 194 + + L+A FID T+LLPD LTLPLLW G+ L L V L DAV+GAMAGY LW Sbjct: 134 LFFSYVLIAATFIDFDTLLLPDQLTLPLLWGGIALALLGFSPVSLSDAVIGAMAGYLSLW 193 Query: 195 LIFWCFKLTTGKEGLGYGDFKLMAALGAWLGWQALPLVLLLASALGAVLGLALMLGGRHQ 254 I+W FKL TGKEG+GYGDFKL+AALGAWLGWQ LP+++LL+S +G + GL + + Sbjct: 194 SIYWLFKLLTGKEGMGYGDFKLLAALGAWLGWQQLPVIVLLSSVVGVIFGLIQLRQQKKG 253 Query: 255 RGQAIPFGPCLALAGMLALVLGH---DW 279 A PFGP LA+AG AL+ G DW Sbjct: 254 IDMAFPFGPYLAIAGWFALLWGDKVIDW 281 >NMB0332 [NOU] COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Nme Neisseria meningitidis MC58 Length = 286 Score = 244 bits (623), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 132/260 (50%), Positives = 169/260 (65%), Gaps = 6/260 (2%) Query: 12 SPVLSGVAALLGLLVGSFLNVVIHRLPAMMLRESANFVAHERGEALPHTER--YNLWLPH 69 SP +AA+ GLLVGSFLNVVI+R+P MM R F L E +NL P Sbjct: 8 SPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKEYLNLPLTEEESRTFNLMKPD 67 Query: 70 SACPHCATPLALHHKLPVLSWLLLRGRCAYCSAPISLRYPLVELLCAVLFALLAWRYGLG 129 S CP C P+ +P++S+LLLRG+CA C IS+RYPL+ELL VLF L+AW+YG Sbjct: 68 SCCPKCRVPIRAWQNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWS 127 Query: 130 LTGLALMTGAAFLVALAFIDAQTMLLPDDLTLPLLWLGLLVNLTHRLVPLQDAVLGAMAG 189 L + AFL++L FIDA T LPD +TLPL+WLGL+ NL VPLQ AVLGA+AG Sbjct: 128 WITLGGLVLTAFLISLTFIDADTQYLPDSMTLPLIWLGLIFNLDGGFVPLQSAVLGAVAG 187 Query: 190 YGVLWLIFWCFKLTTGKEGLGYGDFKLMAALGAWLGWQALPLVLLLASALGAVLGLALML 249 YG LWL+ +KL TGK G+G GDFKL+AALGAWLG ALP+++ ++S +G V + + Sbjct: 188 YGSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLVAAIVM-- 245 Query: 250 GGRHQRGQAIPFGPCLALAG 269 R +GQ FGP L ++G Sbjct: 246 --RVAKGQHFAFGPALTVSG 263 >NMA2156 [NOU] COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases NmA Neisseria meningitidis Z2491 Length = 286 Score = 240 bits (613), Expect = 3e-63, Method: Compositional matrix adjust. Identities = 129/260 (49%), Positives = 168/260 (64%), Gaps = 6/260 (2%) Query: 12 SPVLSGVAALLGLLVGSFLNVVIHRLPAMMLRESANFVAHERGEALPHTER--YNLWLPH 69 SP +AA+ GLLVGSFLNVVI+R+P MM R F L E +NL P Sbjct: 8 SPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKEYLNLPLTEEESRTFNLMKPD 67 Query: 70 SACPHCATPLALHHKLPVLSWLLLRGRCAYCSAPISLRYPLVELLCAVLFALLAWRYGLG 129 S CP C P+ +P++S+LLLRG+CA C IS+RYPL+ELL VLF L+AW+YG Sbjct: 68 SCCPKCRVPIRAWQNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWS 127 Query: 130 LTGLALMTGAAFLVALAFIDAQTMLLPDDLTLPLLWLGLLVNLTHRLVPLQDAVLGAMAG 189 L + AFL++L FIDA T LPD +TLPL+WLGL+ NL VPLQ AVLGA+AG Sbjct: 128 WITLGGLILTAFLISLTFIDADTQYLPDSMTLPLIWLGLIFNLDGGFVPLQSAVLGAVAG 187 Query: 190 YGVLWLIFWCFKLTTGKEGLGYGDFKLMAALGAWLGWQALPLVLLLASALGAVLGLALML 249 YG +WL+ +KL G+ G+G GDFKL+AALGAWLG ALP+++ ++S +G V + + Sbjct: 188 YGSIWLLCAVYKLIKGEIGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLVAAIVM-- 245 Query: 250 GGRHQRGQAIPFGPCLALAG 269 R +GQ FGP L ++G Sbjct: 246 --RVAKGQHFAFGPALTVSG 263 >RSc2827 [NOU] COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Rso Ralstonia solanacearum Length = 294 Score = 228 bits (580), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 143/260 (55%), Positives = 171/260 (65%), Gaps = 1/260 (0%) Query: 17 GVAALLGLLVGSFLNVVIHRLPAMMLRESANFVAHERGEALPHTERYNLWLPHSACPHCA 76 G LLGLLVGSFLNVVIHRLP M+ RE AN++A R E LPH E YNL +P SACP C Sbjct: 21 GAGTLLGLLVGSFLNVVIHRLPRMIEREEANYIAELRNEPLPHPEPYNLVVPRSACPSCG 80 Query: 77 TPLALHHKLPVLSWLLLRGRCAYCSAPISLRYPLVELLCAVLFALLAWRYGLGLTGLALM 136 + +PVLSWL LRGRC+ C PIS RYP VEL+ VL W +G +A Sbjct: 81 HQIKAVENIPVLSWLALRGRCSACKTPISWRYPAVELVTGVLTGACLWHFGPTWVAVASA 140 Query: 137 TGAAFLVALAFIDAQTMLLPDDLTLPLLWLGLLVNLTHRLVPLQDAVLGAMAGYGVLWLI 196 FL+A + IDA T LLPD +T PLLWLGLLVNL L DAV+GA AGY LW I Sbjct: 141 ALLWFLIAGSMIDADTQLLPDAITQPLLWLGLLVNLFSMFARLPDAVIGATAGYLFLWAI 200 Query: 197 FWCFKLTTGKEGLGYGDFKLMAALGAWLGWQALPLVLLLASALGAVLGLALMLGGRHQRG 256 +W +KL G+EG+GYGDFKLM ALGAW GWQALPL++LL+S +G V G+ + G Sbjct: 201 YWAYKLLRGREGMGYGDFKLMGALGAWFGWQALPLLVLLSSVVGLVFGVVRIARGATSE- 259 Query: 257 QAIPFGPCLALAGMLALVLG 276 FGP +A AG++AL+ G Sbjct: 260 SPFSFGPFIAGAGVIALLAG 279 >YPO0806 [NOU] COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Ype Yersinia pestis Length = 280 Score = 205 bits (522), Expect = 8e-53, Method: Compositional matrix adjust. Identities = 117/269 (43%), Positives = 160/269 (59%), Gaps = 10/269 (3%) Query: 21 LLGLLVGSFLNVVIHRLPAMMLRESANFVAH-ERGEALPHTERYNLWLPHSACPHCATPL 79 + G +VGSFLNV+I+RLP M+ S+ +H E + H NL+ P S C HC + Sbjct: 13 IFGAMVGSFLNVLIYRLPIMLANLSSRSESHGEEIKMRSHLRNINLFQPGSFCHHCNESI 72 Query: 80 ALHHKLPVLSWLLLRGRCAYCSAPISLRYPLVELLCAV--LFALLAWRYGLGL-TGLALM 136 + + +P+L W+ LRG C+ IS RY +E+L + L L+ ++ L + T L L+ Sbjct: 73 PIKYNIPILGWIFLRGASRCCNKKISTRYLFIEVLAVIQTLLVLMIFKEDLLICTSLVLI 132 Query: 137 TGAAFLVALAFIDAQTMLLPDDLTLPLLWLGLLVNLTHRLVPLQDAVLGAMAGYGVLWLI 196 L ALAFID T LLPD +T+PLLWLGLL+N+ PL AVLGA++GY LWL Sbjct: 133 WS---LTALAFIDFDTYLLPDCMTIPLLWLGLLINIDTVFAPLTSAVLGAVSGYLFLWLS 189 Query: 197 FWCFKLTTGKEGLGYGDFKLMAALGAWLGWQALPLVLLLASALGAVLGLALMLGGRHQRG 256 +W FK+ G +G+GYGDFKLMAALGAW G A+P ++L +S G V + G Sbjct: 190 YWLFKIVRGVDGMGYGDFKLMAALGAWFGVSAVPFLILFSSFFGLVAYAIFYFFDKKDNG 249 Query: 257 QAIP---FGPCLALAGMLALVLGHDWLNL 282 + I FGP ++LAG+L L LG NL Sbjct: 250 KEINYIAFGPYISLAGVLYLFLGSHVTNL 278