BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0285.p (515 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VC2031 [P] COG0659 Sulfate permease and related transporters (MF... 485 e-136 BH0414 [P] COG0659 Sulfate permease and related transporters (MF... 354 2e-97 PA2563 [P] COG0659 Sulfate permease and related transporters (MF... 354 3e-97 BS_ybaR [P] COG0659 Sulfate permease and related transporters (M... 344 3e-94 AGc2140 [P] COG0659 Sulfate permease and related transporters (M... 336 7e-92 >VC2031 [P] COG0659 Sulfate permease and related transporters (MFS superfamily) Vch Vibrio cholerae Length = 521 Score = 485 bits (1248), Expect = e-136, Method: Compositional matrix adjust. Identities = 258/493 (52%), Positives = 342/493 (69%), Gaps = 10/493 (2%) Query: 28 PPSRLRELRQNVLAGLTTSFALVPECIAFALVAQLNPLMGLYGAFFICTITALFGGRPGM 87 P ++ +VL+GLT + ALVPE +AFA VA ++P++GLY AF + IT++FGGRPGM Sbjct: 7 PSFSQHSIKNDVLSGLTVALALVPEAVAFAFVAGVDPMVGLYAAFIVGLITSIFGGRPGM 66 Query: 88 ISGAAGSMAVVIVALVVQHGAQYFLATVVLSGLIMLAFGALRLGKLVRMVPHPVMLGFVN 147 ISGA G+MAVV+V+LV HG QY A ++L+GL+ +A G +LGK +RMVPHPVM+GFVN Sbjct: 67 ISGATGAMAVVMVSLVASHGVQYLFAAILLTGLLQVAAGLFKLGKFIRMVPHPVMIGFVN 126 Query: 148 GLAIVIALSQLEHFRLHTDSG-LHWLQGSALLIMIGLTLATMLIVWLLPRVTKAIPPALA 206 GLAIVI L+QL F+ +G + WL LL+M+GL TM I+ LP++T AIP +LA Sbjct: 127 GLAIVIFLAQLGQFKAPDLNGVMTWLPQKELLLMLGLVALTMAIIHFLPKLTTAIPSSLA 186 Query: 207 AILTVGLVTYVSGLHTRTL---------GDMAQIAGGLPPLHWPSVPMNLETLHIIGPYA 257 AI+TV L+ GL TRT+ D A +AG LP P+VP+ ETL II PYA Sbjct: 187 AIVTVTLLVQGLGLETRTVVDFLRAMSGNDAATLAGSLPSFSIPAVPLTWETLKIIFPYA 246 Query: 258 VLMAIVGLLETLLTFNLTDEITASRGQPNRECLALGAANIVSGLFGGMGGCAMIGQTMIN 317 +++A +GL+E+LLT + DE+T +RGQ NREC+ G ANI +FG MGGCAMIGQ+MIN Sbjct: 247 LILAAIGLIESLLTLTVLDEMTGTRGQSNRECMGQGLANITCSMFGAMGGCAMIGQSMIN 306 Query: 318 LGSGGRSRLSGVVAGVMILLFILFLSPAIERIPLAALAGVMFVVAQETFAWGSLRVLGKV 377 + SGGR RLSG+VA V++L FILF + IE IPLAAL GVMF+V TF W + ++ +V Sbjct: 307 VNSGGRGRLSGIVAAVLLLCFILFTASLIEMIPLAALVGVMFMVVIGTFEWATFKLARRV 366 Query: 378 PRSDALVIIAVTIITVLTDLAVAVLCGIVIAALNFAWQHAREVRAEQRDEADGSRTYLPH 437 P+ D VI+ VT++TV TDLA+AV G++ +AL FAW+HA+ + A DG + Y H Sbjct: 367 PKQDFFVIVLVTVVTVFTDLAIAVAVGVIASALMFAWEHAKHIYAASHINPDGHKEYHIH 426 Query: 438 GTLFFASTTRFLELFDTQNDPQQVTLDCRYLRLADHSAIAAVQTLAERYVRAGKVLRVMA 497 G +FF S FLELFD +DP++V +D R+ADHSAI A++TLAERY GK L + Sbjct: 427 GPIFFGSAANFLELFDAHHDPKEVIVDFARSRVADHSAIDAIETLAERYAAVGKTLHLRH 486 Query: 498 LSQRCSQLLQRAG 510 LSQ C LLQ+ G Sbjct: 487 LSQDCRALLQKVG 499 >BH0414 [P] COG0659 Sulfate permease and related transporters (MFS superfamily) Bha Bacillus halodurans Length = 486 Score = 354 bits (909), Expect = 2e-97, Method: Compositional matrix adjust. Identities = 199/479 (41%), Positives = 294/479 (61%), Gaps = 15/479 (3%) Query: 34 ELRQNVLAGLTTSFALVPECIAFALVAQLNPLMGLYGAFFICTITALFGGRPGMISGAAG 93 +R +VLAG+ + AL+PE IAF+++A ++P++GLY +F I + A GGRPGMIS A G Sbjct: 13 NVRGDVLAGIVVALALIPEAIAFSIIAGVDPMVGLYASFCIAVVIAFVGGRPGMISAATG 72 Query: 94 SMAVVIVALVVQHGAQYFLATVVLSGLIMLAFGALRLGKLVRMVPHPVMLGFVNGLAIVI 153 +MA++++ LV HG Y LA +L+G++ + FG +L +++ VP VM+GFVN LAI+I Sbjct: 73 AMALLMINLVADHGLHYLLAATILTGVLQILFGVFKLASVMKFVPRSVMIGFVNALAILI 132 Query: 154 ALSQLEHFRLHTDSGLHWLQGSALLIMIGLTLATMLIVWLLPRVTKAIPPALAAILTVGL 213 SQL+HF G W +M L T+ I++LLP+VT A+P L AI+ V Sbjct: 133 FTSQLQHF-----VGETW-------VMYALVALTLAIIYLLPKVTTAVPSTLVAIIIVTA 180 Query: 214 VTYVSGLHTRTLGDMAQIAGGLPPLHWPSVPMNLETLHIIGPYAVLMAIVGLLETLLTFN 273 + + RT+GD+ + LP PSVP + ETL II PY++ +AIVGLLE+LLT N Sbjct: 181 IVIFGNIGVRTVGDLGTLTQSLPTFLIPSVPFSFETLMIIFPYSLALAIVGLLESLLTAN 240 Query: 274 LTDEITASRGQPNRECLALGAANIVSGLFGGMGGCAMIGQTMINLGSGGRSRLSGVVAGV 333 + D++T + N+E G ANIV+G FGGM GCAMIGQ++IN+ SGGR RLS +VAGV Sbjct: 241 IVDDMTDTESDKNKESRGQGIANIVTGFFGGMAGCAMIGQSVINVKSGGRGRLSALVAGV 300 Query: 334 MILLFILFLSPAIERIPLAALAGVMFVVAQETFAWGSLRVLGKVPRSDALVIIAVTIITV 393 ++ I+ L + +IP+AALAGVM +V+ TF W SLR L K+PR+DA V++ V Sbjct: 301 FLMFLIIVLGNVVVQIPMAALAGVMIMVSIGTFDWSSLRNLHKIPRTDATVMVVTVGTVV 360 Query: 394 LT-DLAVAVLCGIVIAALNFAWQHAREVRAEQRDEADGS-RTYLPHGTLFFASTTRFLEL 451 T DL+ VL G+V++A+ FA + +R V+ E+ A + Y G LFFAS + Sbjct: 361 YTHDLSKGVLAGVVLSAIFFAAKISR-VKVEEMTSATPELKRYKVQGQLFFASVSDLPAK 419 Query: 452 FDTQNDPQQVTLDCRYLRLADHSAIAAVQTLAERYVRAGKVLRVMALSQRCSQLLQRAG 510 F + +V +D + D SA+ A+ + ++ + + L+ +L+QR G Sbjct: 420 FSYMANVNEVEIDLSEAHVWDDSAVGALDKIEMKFEQQNIKVTFTGLNTESRKLVQRMG 478 >PA2563 [P] COG0659 Sulfate permease and related transporters (MFS superfamily) Pae Pseudomonas aeruginosa Length = 495 Score = 354 bits (908), Expect = 3e-97, Method: Compositional matrix adjust. Identities = 203/484 (41%), Positives = 299/484 (61%), Gaps = 15/484 (3%) Query: 34 ELRQNVLAGLTTSFALVPECIAFALVAQLNPLMGLYGAFFICTITALFGGRPGMISGAAG 93 LR ++LAGL + AL+PE IAF+++A ++P +GLY +F + + A GGRPGMIS A G Sbjct: 12 NLRGDLLAGLVVALALIPEAIAFSIIAGVDPKIGLYASFSMAVVIAFAGGRPGMISAATG 71 Query: 94 SMAVVIVALVVQHGAQYFLATVVLSGLIMLAFGALRLGKLVRMVPHPVMLGFVNGLAIVI 153 +MA+++V LV HG QY LA +L G++ + G LRLG L+R V V+ GFVN LAI+I Sbjct: 72 AMALLMVNLVKDHGLQYLLAATLLCGVLQILAGYLRLGSLMRFVSRSVVTGFVNALAILI 131 Query: 154 ALSQLEHFRLHTDSG--LHWLQGSALLIMIGLTLATMLIVWLLPRVTKAIPPALAAILTV 211 ++QL TD G ++ + + L I+ G LPR+ + +P L IL + Sbjct: 132 FMAQLPEL---TDVGWPVYAMTAAGLAIVYGFPH--------LPRIGRLLPSPLVCILVL 180 Query: 212 GLVTYVSGLHTRTLGDMAQIAGGLPPLHWPSVPMNLETLHIIGPYAVLMAIVGLLETLLT 271 ++ GL RT+GDM Q+ LP WP VP+NL+TL I+ PY+ +A+VGLLE+L+T Sbjct: 181 TGISIYLGLDIRTVGDMGQLPDSLPLFLWPDVPLNLDTLLIVLPYSAALAVVGLLESLMT 240 Query: 272 FNLTDEITASRGQPNRECLALGAANIVSGLFGGMGGCAMIGQTMINLGSGGRSRLSGVVA 331 + DE+T + NREC G ANI +GL GGM GCAMIGQ++IN+ SGGRSRLS +VA Sbjct: 241 ATIVDEMTDTGSDKNRECKGQGLANIATGLLGGMAGCAMIGQSVINVKSGGRSRLSTLVA 300 Query: 332 GVMILLFILFLSPAIERIPLAALAGVMFVVAQETFAWGSLRVLGKVPRSDALV-IIAVTI 390 GV +LL ++FLS + RIP+AAL VM +V+ TF W S+R L + P S LV ++ V + Sbjct: 301 GVALLLMVVFLSDWVGRIPMAALVAVMIMVSIGTFRWESIRNLKRYPLSTNLVMLVTVGV 360 Query: 391 ITVLTDLAVAVLCGIVIAALNFAWQHAREVRAEQRDEADGSRT-YLPHGTLFFASTTRFL 449 + +LA V+ G+++A+L FA + + + ADG+R Y G +FFAS+ RF+ Sbjct: 361 VLATHNLAFGVVAGVLLASLFFANKIGHYLDIDSERSADGTRRHYQVSGQVFFASSGRFV 420 Query: 450 ELFDTQNDPQQVTLDCRYLRLADHSAIAAVQTLAERYVRAGKVLRVMALSQRCSQLLQRA 509 FD + + V +D R+ L D +A+AA+ + + + G + V+ L+ + L+ R Sbjct: 421 AAFDLKETLEHVLIDLRHAHLWDVTAVAALDKVVLGFRQRGVQVDVLGLNAASATLVDRF 480 Query: 510 GLPD 513 G D Sbjct: 481 GAYD 484 >BS_ybaR [P] COG0659 Sulfate permease and related transporters (MFS superfamily) Bsu Bacillus subtilis Length = 478 Score = 344 bits (883), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 184/476 (38%), Positives = 284/476 (59%), Gaps = 14/476 (2%) Query: 34 ELRQNVLAGLTTSFALVPECIAFALVAQLNPLMGLYGAFFICTITALFGGRPGMISGAAG 93 +R+++LAG+ + AL+PE I F+++A ++P++GLY +F I I ++FGGRPGMIS A G Sbjct: 14 NIRKDILAGILVALALIPEAIGFSIIAGVDPMVGLYASFCIAIIISIFGGRPGMISAATG 73 Query: 94 SMAVVIVALVVQHGAQYFLATVVLSGLIMLAFGALRLGKLVRMVPHPVMLGFVNGLAIVI 153 SMAVV+V+LV HG QY A +L+G+I + G ++ +L++ +P VM+GFVN LAI+I Sbjct: 74 SMAVVMVSLVADHGLQYLFAATILTGIIQVILGISKIARLMKFIPRSVMIGFVNALAILI 133 Query: 154 ALSQLEHFRLHTDSGLHWLQGSALLIMIGLTLATMLIVWLLPRVTKAIPPALAAILTVGL 213 +QL F G W M + +++I+++LPR T A+P L AI+ + + Sbjct: 134 FSAQLPQFE-----GASWS-------MYAMLAGSLVIIYVLPRFTTAVPSPLVAIIVMTI 181 Query: 214 VTYVSGLHTRTLGDMAQIAGGLPPLHWPSVPMNLETLHIIGPYAVLMAIVGLLETLLTFN 273 + + RT+GDM I+ LP P VP ETL II PY++ +A VGLLE+LLT Sbjct: 182 IAVTFHVDVRTVGDMGNISSSLPHFLIPDVPFTFETLQIIFPYSIALAFVGLLESLLTAQ 241 Query: 274 LTDEITASRGQPNRECLALGAANIVSGLFGGMGGCAMIGQTMINLGSGGRSRLSGVVAGV 333 + DE+T + N+E G ANIV+G FGGM GCAMIGQ++IN +GGR RLS VAG Sbjct: 242 IIDEMTDTDSDKNKESRGQGIANIVTGFFGGMAGCAMIGQSVINTKAGGRGRLSAFVAGA 301 Query: 334 MILLFILFLSPAIERIPLAALAGVMFVVAQETFAWGSLRVLGKVPRSDAL-VIIAVTIIT 392 ++ I LS + +IP+AAL VM +V+ TF W SL+ L K P +D++ +++ V + Sbjct: 302 FLMFLIAVLSHVVVKIPMAALVAVMVMVSVGTFDWSSLKGLKKAPLTDSIVMVVTVVTVV 361 Query: 393 VLTDLAVAVLCGIVIAALNFAWQHAREVRAEQRDEADGSRTYLPHGTLFFASTTRFLELF 452 V DL+ V G++++A+ F + ++ ++ E RTY G +FFAS T F Sbjct: 362 VTDDLSKGVFVGVLLSAVFFVAKISK-LKIVSHAEDQKLRTYQVKGQIFFASVTDLTNAF 420 Query: 453 DTQNDPQQVTLDCRYLRLADHSAIAAVQTLAERYVRAGKVLRVMALSQRCSQLLQR 508 Q D ++V +D + D S AA+ + ++ G + L++ L+++ Sbjct: 421 IYQEDIERVVIDLTEAHVWDDSGAAALDKIVAKFKEQGIEAELKGLNKASKSLMKQ 476 >AGc2140 [P] COG0659 Sulfate permease and related transporters (MFS superfamily) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 604 Score = 336 bits (862), Expect = 7e-92, Method: Compositional matrix adjust. Identities = 202/520 (38%), Positives = 306/520 (58%), Gaps = 22/520 (4%) Query: 2 YRLSFSFFAAPLAAPAHSLPMTTIATPPSRLRE----LRQNVLAGLTTSFALVPECIAFA 57 +R SF + L HSL + + RE +R +VL+G+ + AL+PE I F+ Sbjct: 89 HRHSFLIYRTRLRPVRHSLRKNQMNRFQTYRREWFSNIRGDVLSGIVVALALIPEAIGFS 148 Query: 58 LVAQLNPLMGLYGAFFICTITALFGGRPGMISGAAGSMAVVIVALVVQHGAQYFLATVVL 117 ++A ++P +GL+ +F I ++A GGRPGMIS A + AV++V LV +HG QY A +L Sbjct: 149 VIAGVDPKVGLFASFAIACVSAFTGGRPGMISAATAATAVLMVTLVKEHGLQYLFAATIL 208 Query: 118 SGLIMLAFGALRLGKLVRMVPHPVMLGFVNGLAIVIALSQL-EHFRLHTDSGLHWLQGSA 176 G++ +A G +LG+++R V VM GFVN LAI+I ++QL E + ++ Sbjct: 209 MGVLQIAAGFAKLGRVMRFVSRSVMTGFVNALAILIFMAQLPELIGVPVET--------- 259 Query: 177 LLIMIGLTLATMLIVWLLPRVTKAIPPALAAILTVGLVTYVSGLHTRTLGDMAQIAGGLP 236 +MI LA I++L P VTK IP L AI+ + V SG+ RT+GD+ ++ LP Sbjct: 260 -YVMIAAGLA---IIYLFPLVTKIIPSPLVAIVALTCVAVFSGMDIRTVGDLGELPSTLP 315 Query: 237 PLHWPSVPMNLETLHIIGPYAVLMAIVGLLETLLTFNLTDEITASRGQPNRECLALGAAN 296 P VP+ ETL II PY++ +A VGLLE+LLT + D++T + ++EC+ G +N Sbjct: 316 IFALPQVPLTFETLQIIFPYSIALAAVGLLESLLTAQIVDDMTDTGSNKSQECIGQGTSN 375 Query: 297 IVSGLFGGMGGCAMIGQTMINLGSGGRSRLSGVVAGVMILLFILFLSPAIERIPLAALAG 356 I S L GGMGGCAMIGQ++IN+ SGGR RLS VAG +L IL L + IP+AAL Sbjct: 376 IASALIGGMGGCAMIGQSVINVRSGGRGRLSTFVAGAFLLFLILVLDDLVRIIPMAALVA 435 Query: 357 VMFVVAQETFAWGSLRVLGKVPRSDALVIIAVTIITVLT--DLAVAVLCGIVIAALNFAW 414 VM +V+ TF+W S+ L + P S ++V++ VT+ TVL DLA VL G++++ + FA Sbjct: 436 VMIMVSIGTFSWRSILDLTRNPPSSSIVML-VTVGTVLATHDLAKGVLAGVLLSGVFFAG 494 Query: 415 QHAREVRAEQRDEADG-SRTYLPHGTLFFASTTRFLELFDTQNDPQQVTLDCRYLRLADH 473 + ++ ADG R Y G +FFAST F+ FD + + VT+D L D Sbjct: 495 KVSKLFHVRPELSADGRERIYRVDGQIFFASTESFIAAFDFAEEVEAVTIDVTQAHLWDI 554 Query: 474 SAIAAVQTLAERYVRAGKVLRVMALSQRCSQLLQRAGLPD 513 SA+ A+ + ++ + GK + V+ +++ + ++ R L D Sbjct: 555 SAVGALDKVVLKFRKTGKRVEVIGVNEASAHMIDRFALHD 594