BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0276.p (280 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGc3682 [R] COG0656 Aldo/keto reductases, related to diketogulon... 351 8e-97 SMc01429 [R] COG0656 Aldo/keto reductases, related to diketogulo... 331 1e-90 mlr5327 [R] COG0656 Aldo/keto reductases, related to diketogulon... 316 3e-86 PA0804 [R] COG0656 Aldo/keto reductases, related to diketogulona... 306 4e-83 yeaE [R] COG0656 Aldo/keto reductases, related to diketogulonate... 303 4e-82 >AGc3682 [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 281 Score = 351 bits (901), Expect = 8e-97, Method: Compositional matrix adjust. Identities = 169/279 (60%), Positives = 206/279 (73%) Query: 2 KQIPLITLRNGAQVPTLGQGTWNMGESGAAAATEVRALQAGIDLGMTLIDTAEMYADGNA 61 + IP +TL +G +VP LG GTWNMGE+ ++A E+ +++ IDLGMTL+DTAEMYADG + Sbjct: 3 EDIPAVTLPSGNEVPALGLGTWNMGETRSSADDEIESIRKAIDLGMTLVDTAEMYADGRS 62 Query: 62 ERIVGQAIAGRRQQVYLVSKVLPHNASQRGTIAACEASLKRLGTDHIELYLLHWRGPHPL 121 E +VG AIAGRR +V+LVSKV P NAS RGT ACE SL RLGTDHI+LYLLHWRG HPL Sbjct: 63 EEVVGTAIAGRRDEVFLVSKVYPWNASARGTAEACERSLARLGTDHIDLYLLHWRGEHPL 122 Query: 122 AATVEGMEKLVAQGKIGGWGVSNLDSDDIDELLQEPQGSHYLCNQVLYNLSRRGIEYDLL 181 TV E+L + GKIG WGVSN D+DD++EL P+G + NQVLYNLSRRG E+ LL Sbjct: 123 GETVAAFERLKSDGKIGNWGVSNFDTDDMEELFTVPEGKNCAANQVLYNLSRRGPEFSLL 182 Query: 182 PQALEQGVAIMAYSPIEQGRILKNATLGTVAQRHGVTPAQVALAWVLRRPGVIAIPKAAD 241 P E GV +MAYSPIEQGRILKN L +A+ + TPAQ+ALA++L R GVIAIPK+A Sbjct: 183 PWCQEHGVPLMAYSPIEQGRILKNHELIRIAKAYQATPAQLALAFLLDRDGVIAIPKSAS 242 Query: 242 TAHVQANRACLDLQLTAADLKELDAAFPPPRRKQPLAML 280 + + NR DL++T D LDAAFPPP RK L ML Sbjct: 243 VSRIVENRGATDLEITEEDWTALDAAFPPPTRKTSLEML 281 >SMc01429 [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase Sme Sinorhizobium meliloti Length = 281 Score = 331 bits (848), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 161/277 (58%), Positives = 200/277 (72%) Query: 4 IPLITLRNGAQVPTLGQGTWNMGESGAAAATEVRALQAGIDLGMTLIDTAEMYADGNAER 63 IP I +G +VP LGQGTW MGE+ A A EVR+LQ G+DLGMTLIDTAEMY DG AER Sbjct: 5 IPTIAFPDGRKVPALGQGTWRMGENRAKTADEVRSLQTGLDLGMTLIDTAEMYGDGAAER 64 Query: 64 IVGQAIAGRRQQVYLVSKVLPHNASQRGTIAACEASLKRLGTDHIELYLLHWRGPHPLAA 123 IVG+AI GRR + ++VSKVLP NAS+ GT+AACE SL+ LG D ++LYLLHWRG +PLA Sbjct: 65 IVGEAIKGRRDEAFVVSKVLPSNASRAGTVAACERSLRNLGIDCVDLYLLHWRGGYPLAE 124 Query: 124 TVEGMEKLVAQGKIGGWGVSNLDSDDIDELLQEPQGSHYLCNQVLYNLSRRGIEYDLLPQ 183 TV E+L GKI WGVSN D DD++EL P G + NQVLYNL+RRGIE+DLLP+ Sbjct: 125 TVAAFEELKKAGKIRAWGVSNFDVDDMEELSAVPDGGNVAANQVLYNLARRGIEFDLLPR 184 Query: 184 ALEQGVAIMAYSPIEQGRILKNATLGTVAQRHGVTPAQVALAWVLRRPGVIAIPKAADTA 243 QGV +MAYSP+++GR+L +A L +A+ H TPAQVALA++ GVI+IPK Sbjct: 185 CRAQGVPVMAYSPLDEGRLLHDADLIHIAKAHQATPAQVALAFLKTCSGVISIPKTGSPE 244 Query: 244 HVQANRACLDLQLTAADLKELDAAFPPPRRKQPLAML 280 + NR +D+ LT +L ELD FPPPRRK L ++ Sbjct: 245 RARENRDAMDIHLTTENLAELDRHFPPPRRKTRLEVI 281 >mlr5327 [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase Mlo Mesorhizobium loti Length = 281 Score = 316 bits (810), Expect = 3e-86, Method: Compositional matrix adjust. Identities = 157/273 (57%), Positives = 194/273 (71%) Query: 8 TLRNGAQVPTLGQGTWNMGESGAAAATEVRALQAGIDLGMTLIDTAEMYADGNAERIVGQ 67 TL +G V LGQGTW MGE A EV AL+ G+DLG+TLIDTAEMYA G AE +V + Sbjct: 9 TLPSGETVQVLGQGTWKMGEDSRRRADEVNALKLGLDLGLTLIDTAEMYASGGAEEVVAE 68 Query: 68 AIAGRRQQVYLVSKVLPHNASQRGTIAACEASLKRLGTDHIELYLLHWRGPHPLAATVEG 127 AIAGRR +V++VSKVLP NAS G ACE SLKRL TD I+LYLLHW G PLA TVE Sbjct: 69 AIAGRRAEVFVVSKVLPSNASHAGVQRACENSLKRLRTDRIDLYLLHWPGSVPLAETVEA 128 Query: 128 MEKLVAQGKIGGWGVSNLDSDDIDELLQEPQGSHYLCNQVLYNLSRRGIEYDLLPQALEQ 187 E + GKI WGVSN D++D+D+L P GS+ NQVLYNL RRG E+DL P + ++ Sbjct: 129 FEAVKKAGKIRHWGVSNFDTEDMDDLAGLPDGSNVQTNQVLYNLVRRGPEFDLAPWSRKR 188 Query: 188 GVAIMAYSPIEQGRILKNATLGTVAQRHGVTPAQVALAWVLRRPGVIAIPKAADTAHVQA 247 G+ +MAYSP+EQG + +N L VA RH T AQ+ALAWV+ + G+IAIPKA+ HV+ Sbjct: 189 GIPLMAYSPVEQGALARNTGLDAVAARHNATAAQIALAWVMHQDGIIAIPKASSQEHVRQ 248 Query: 248 NRACLDLQLTAADLKELDAAFPPPRRKQPLAML 280 N A LD++LT D+ +LD AFPPP RK+ L M+ Sbjct: 249 NFAALDIKLTPQDITDLDRAFPPPTRKRGLEMI 281 >PA0804 [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase Pae Pseudomonas aeruginosa Length = 273 Score = 306 bits (783), Expect = 4e-83, Method: Compositional matrix adjust. Identities = 158/275 (57%), Positives = 201/275 (73%), Gaps = 6/275 (2%) Query: 7 ITLRNGAQVPTLGQGTWNMGESGAAAATEVRALQAGIDLGMTLIDTAEMYADGNAERIVG 66 +TL +G +V +GQGTW++GE EV AL+ GI+LGMTLIDTAEMYA+G AE +VG Sbjct: 4 LTLIDGQEVAAIGQGTWHIGEQPGERKREVAALREGIELGMTLIDTAEMYAEGGAEDVVG 63 Query: 67 QAIAGRRQQVYLVSKVLPHNASQRGTIAACEASLKRLGTDHIELYLLHWRGPHPLAATVE 126 AIAGRR++V+LVSKV PHNAS+ G AACE SL+RLG + I+LYLLHW+G +PL T+E Sbjct: 64 AAIAGRREEVFLVSKVYPHNASREGLPAACERSLRRLGCETIDLYLLHWQGRYPLEETIE 123 Query: 127 GMEKLVAQGKIGGWGVSNLDSDDIDELLQEPQGSHYLCNQVLYNLSRRGIEYDLLPQALE 186 E+L QGKI WGVSN D D+ EL GS NQV+YNL RGIEYDLLP E Sbjct: 124 AFERLRDQGKILRWGVSNFDLGDMYEL----DGSACAANQVMYNLEERGIEYDLLPWCQE 179 Query: 187 QGVAIMAYSPIEQ-GRILKNATLGTVAQRHGVTPAQVALAWVLRRPGVIAIPKAADTAHV 245 +G+ +MAY P+ Q GR+L++ LG +A RH + AQVALAW+L + GVIAIPKA +AH+ Sbjct: 180 RGMPVMAYCPVGQGGRLLRHPALGEIAARHDASSAQVALAWLLEQ-GVIAIPKAVTSAHI 238 Query: 246 QANRACLDLQLTAADLKELDAAFPPPRRKQPLAML 280 + N A DL+L+A DL+ LD AFPPP RK+ LA++ Sbjct: 239 RLNAAAADLELSADDLRALDQAFPPPTRKRNLAIV 273 >yeaE [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase Eco Escherichia coli K12 Length = 284 Score = 303 bits (775), Expect = 4e-82, Method: Compositional matrix adjust. Identities = 154/283 (54%), Positives = 197/283 (69%), Gaps = 5/283 (1%) Query: 3 QIPLITLRNGAQVPTLGQGTWNMGESGAAAATEVRALQAGIDLGMTLIDTAEMYADGNAE 62 Q +I +P +GQGTW MGE + TEV AL+AGI+LG+TLIDTAEMYADG AE Sbjct: 2 QQKMIQFSGDVSLPAVGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAE 61 Query: 63 RIVGQAIAGRRQQVYLVSKVLPHNASQRGTIAACEASLKRLGTDHIELYLLHWRGPHPLA 122 ++VG+A+ G R++V+LVSKV P NA + I ACEASL+RL TD+++LYLLHW G Sbjct: 62 KVVGEALTGLREKVFLVSKVYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAFE 121 Query: 123 ATVEGMEKLVAQGKIGGWGVSNLDSDDIDELLQEPQGSHYLCNQVLYNLSRRGIEYDLLP 182 TV MEKL+AQGKI WGVSNLD D+ EL Q P G+ NQVLY+L RGIEYDLLP Sbjct: 122 ETVAAMEKLIAQGKIRRWGVSNLDYADMQELWQLPGGNQCATNQVLYHLGSRGIEYDLLP 181 Query: 183 QALEQGVAIMAYSPIEQ-GR----ILKNATLGTVAQRHGVTPAQVALAWVLRRPGVIAIP 237 +Q + +MAYSP+ Q GR +LKNA + +A H ++ AQV LAWV+ GV+AIP Sbjct: 182 WCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISAAQVLLAWVISHQGVMAIP 241 Query: 238 KAADTAHVQANRACLDLQLTAADLKELDAAFPPPRRKQPLAML 280 KAA AHVQ N A L+++L++A+L LD A+P P+ K L M+ Sbjct: 242 KAATIAHVQQNAAVLEVELSSAELAMLDKAYPAPKGKTALDMV 284