BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0262.p (405 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM2372 [GEPR] COG0477 Permeases of the major facilitator superf... 304 3e-82 yfcJ [GEPR] COG0477 Permeases of the major facilitator superfami... 288 2e-77 ECs3206 [GEPR] COG0477 Permeases of the major facilitator superf... 287 3e-77 Z3585 [GEPR] COG0477 Permeases of the major facilitator superfam... 285 2e-76 yhhS [GEPR] COG0477 Permeases of the major facilitator superfami... 262 1e-69 >STM2372 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 392 Score = 304 bits (778), Expect = 3e-82, Method: Compositional matrix adjust. Identities = 173/373 (46%), Positives = 244/373 (65%), Gaps = 2/373 (0%) Query: 24 LKLAPLTLAVFIAFLTIGLQLPVLPLHLKDALGMNATVVGVVVGAQFAAALLSRSWAGNY 83 L + AVF+ ++T+GL LPV+PL + LG + T+VG+ VG QF A +L+R +AG Sbjct: 15 FSLFRIAFAVFLTYMTVGLPLPVIPLFVHHELGYSNTMVGIAVGIQFFATVLTRGYAGRL 74 Query: 84 ADLRGAKRAVLGGFTAASLSGLVYLASLAW-LDHPVASVLVLLLGRLLLALGESLVVTGT 142 AD GAKR+ L G A L+G +L + + PV L L++GRL+L GES ++TGT Sbjct: 75 ADQYGAKRSALQGMLACGLAGAAWLLAALLPVSAPVKFAL-LIVGRLILGFGESQLLTGT 133 Query: 143 MSWGIALVGPQHGGKVMAWLGIAIYAAMACGAPLGVAVNHAYGFAGIAGVSVLIPLLALL 202 ++WG+ LVGP GKVM+W G+AIY A+A GAPLG+ ++ +GFA +AG ++++PLLA Sbjct: 134 LTWGLGLVGPTRSGKVMSWNGMAIYGALAAGAPLGLLIHSHFGFAALAGTTMVLPLLAWA 193 Query: 203 MLAGLPAVAPSANRRTPFYKVLGAVWQPGLGLALSSVGFGVITAFIALLFAAHAWGDSSL 262 + V R + V+G +W+PGLGLAL VGF VI FI+L F ++ W + Sbjct: 194 FNGTVRKVPAYTGERPSLWSVVGLIWKPGLGLALQGVGFAVIGTFISLYFVSNGWTMAGF 253 Query: 263 AFTSFGIAFIVARLLFAHLPDKVGGARVALVCVVIEVLGQLLIWQAGSASWAYAGAALTG 322 T+FG AF++ R+LF +PD+ GG +VA+V +++E G LL+W A +A A GAALTG Sbjct: 254 TLTAFGGAFVLMRILFGWMPDRFGGVKVAVVSLLVETAGLLLLWLAPTAWIALVGAALTG 313 Query: 323 FGYSLVFPGFGVEAMRRAPPQTRGLAMGAYVAFLDISLGITSPLAGALASHYGVSSVYLA 382 G SL+FP GVE ++R P Q RG A+G Y AF DIS G+T PLAG LA+ YG SV+LA Sbjct: 314 AGCSLIFPALGVEVVKRVPAQVRGTALGGYAAFQDISYGVTGPLAGMLATSYGYPSVFLA 373 Query: 383 GAVVVGLSMLVAL 395 GA+ + +LV + Sbjct: 374 GAISAVVGILVTI 386 >yfcJ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 392 Score = 288 bits (736), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 170/372 (45%), Positives = 244/372 (65%) Query: 24 LKLAPLTLAVFIAFLTIGLQLPVLPLHLKDALGMNATVVGVVVGAQFAAALLSRSWAGNY 83 L + AVF+ ++T+GL LPV+PL + LG T+VG+ VG QF A +L+R +AG Sbjct: 15 FSLFRIAFAVFLTYMTVGLPLPVIPLFVHHELGYGNTMVGIAVGIQFLATVLTRGYAGRL 74 Query: 84 ADLRGAKRAVLGGFTAASLSGLVYLASLAWLDHPVASVLVLLLGRLLLALGESLVVTGTM 143 AD GAKR+ L G A L+G L + +L++GRL+L GES ++TG + Sbjct: 75 ADQYGAKRSALQGMLACGLAGGALLLAAILPVSAPFKFALLVVGRLILGFGESQLLTGAL 134 Query: 144 SWGIALVGPQHGGKVMAWLGIAIYAAMACGAPLGVAVNHAYGFAGIAGVSVLIPLLALLM 203 +WG+ +VGP+H GKVM+W G+AIY A+A GAPLG+ ++ YGFA +A ++++P+LA Sbjct: 135 TWGLGIVGPKHSGKVMSWNGMAIYGALAVGAPLGLLIHSHYGFAALAITTMVLPVLAWAC 194 Query: 204 LAGLPAVAPSANRRTPFYKVLGAVWQPGLGLALSSVGFGVITAFIALLFAAHAWGDSSLA 263 + V A R + V+G +W+PGLGLAL VGF VI F++L FA+ W + Sbjct: 195 NGTVRKVPALAGERPSLWSVVGLIWKPGLGLALQGVGFAVIGTFVSLYFASKGWAMAGFT 254 Query: 264 FTSFGIAFIVARLLFAHLPDKVGGARVALVCVVIEVLGQLLIWQAGSASWAYAGAALTGF 323 T+FG AF+V R++F +PD+ GG +VA+V +++E +G LL+WQA A A AGAALTG Sbjct: 255 LTAFGGAFVVMRVMFGWMPDRFGGVKVAIVSLLVETVGLLLLWQAPGAWVALAGAALTGA 314 Query: 324 GYSLVFPGFGVEAMRRAPPQTRGLAMGAYVAFLDISLGITSPLAGALASHYGVSSVYLAG 383 G SL+FP GVE ++R P Q RG A+G Y AF DI+LG++ PLAG LA+ +G SSV+LAG Sbjct: 315 GCSLIFPALGVEVVKRVPSQVRGTALGGYAAFQDIALGVSGPLAGMLATTFGYSSVFLAG 374 Query: 384 AVVVGLSMLVAL 395 A+ L ++V + Sbjct: 375 AISAVLGIIVTI 386 >ECs3206 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 392 Score = 287 bits (734), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 171/372 (45%), Positives = 243/372 (65%) Query: 24 LKLAPLTLAVFIAFLTIGLQLPVLPLHLKDALGMNATVVGVVVGAQFAAALLSRSWAGNY 83 L + AVF+ ++T+GL LPV+PL + LG T+VG+ VG QF A +L+R +AG Sbjct: 15 FSLFRIAFAVFLTYMTVGLPLPVIPLFVHHDLGYGNTMVGIAVGIQFLATVLTRGYAGRL 74 Query: 84 ADLRGAKRAVLGGFTAASLSGLVYLASLAWLDHPVASVLVLLLGRLLLALGESLVVTGTM 143 AD GAKR+ L G A L+G L + +L++GRL+L GES ++TG + Sbjct: 75 ADQYGAKRSALQGMLACGLAGGALLLAAILPVSAPFKFALLVIGRLILGFGESQLLTGAL 134 Query: 144 SWGIALVGPQHGGKVMAWLGIAIYAAMACGAPLGVAVNHAYGFAGIAGVSVLIPLLALLM 203 +WG+ +VGP+H GKVM+W G+AIY A+A GAPLG+ ++ YGFA +A ++ +PLLA Sbjct: 135 TWGLGIVGPKHSGKVMSWNGMAIYGALAVGAPLGLLIHSHYGFAALALTTMALPLLAWAC 194 Query: 204 LAGLPAVAPSANRRTPFYKVLGAVWQPGLGLALSSVGFGVITAFIALLFAAHAWGDSSLA 263 + V A R + V+G +W+PGLGLAL VGF VI F++L FA+ W + Sbjct: 195 NGTVRKVPALAGERPSLWSVVGLIWKPGLGLALQGVGFAVIGTFVSLYFASKGWAMAGFT 254 Query: 264 FTSFGIAFIVARLLFAHLPDKVGGARVALVCVVIEVLGQLLIWQAGSASWAYAGAALTGF 323 T+FG AF+V R++F +PD+ GG +VA+V +++E +G LL+WQA A A AGAALTG Sbjct: 255 LTAFGGAFVVMRVMFGWMPDRFGGVKVAIVSLLVETVGLLLLWQAPGAWVALAGAALTGA 314 Query: 324 GYSLVFPGFGVEAMRRAPPQTRGLAMGAYVAFLDISLGITSPLAGALASHYGVSSVYLAG 383 G SL+FP GVE ++R P Q RG A+G Y AF DI+LG++ PLAG LA+ +G SSV+LAG Sbjct: 315 GCSLIFPALGVEVVKRVPSQVRGTALGGYAAFQDIALGVSGPLAGMLATTFGYSSVFLAG 374 Query: 384 AVVVGLSMLVAL 395 A+ L ++V + Sbjct: 375 AISAVLGIIVTI 386 >Z3585 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 392 Score = 285 bits (728), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 170/372 (45%), Positives = 242/372 (65%) Query: 24 LKLAPLTLAVFIAFLTIGLQLPVLPLHLKDALGMNATVVGVVVGAQFAAALLSRSWAGNY 83 L + AVF+ ++T+ L LPV+PL + LG T+VG+ VG QF A +L+R +AG Sbjct: 15 FSLFRIAFAVFLTYMTVXLPLPVIPLFVHHDLGYGNTMVGIAVGIQFLATVLTRGYAGRL 74 Query: 84 ADLRGAKRAVLGGFTAASLSGLVYLASLAWLDHPVASVLVLLLGRLLLALGESLVVTGTM 143 AD GAKR+ L G A L+G L + +L++GRL+L GES ++TG + Sbjct: 75 ADQYGAKRSALQGMLACGLAGGALLLAAILPVSAPFKFALLVIGRLILGFGESQLLTGAL 134 Query: 144 SWGIALVGPQHGGKVMAWLGIAIYAAMACGAPLGVAVNHAYGFAGIAGVSVLIPLLALLM 203 +WG+ +VGP+H GKVM+W G+AIY A+A GAPLG+ ++ YGFA +A ++ +PLLA Sbjct: 135 TWGLGIVGPKHSGKVMSWNGMAIYGALAVGAPLGLLIHSHYGFAALALTTMALPLLAWAC 194 Query: 204 LAGLPAVAPSANRRTPFYKVLGAVWQPGLGLALSSVGFGVITAFIALLFAAHAWGDSSLA 263 + V A R + V+G +W+PGLGLAL VGF VI F++L FA+ W + Sbjct: 195 NGTVRKVPALAGERPSLWSVVGLIWKPGLGLALQGVGFAVIGTFVSLYFASKGWAMAGFT 254 Query: 264 FTSFGIAFIVARLLFAHLPDKVGGARVALVCVVIEVLGQLLIWQAGSASWAYAGAALTGF 323 T+FG AF+V R++F +PD+ GG +VA+V +++E +G LL+WQA A A AGAALTG Sbjct: 255 LTAFGGAFVVMRVMFGWMPDRFGGVKVAIVSLLVETVGLLLLWQAPGAWVALAGAALTGA 314 Query: 324 GYSLVFPGFGVEAMRRAPPQTRGLAMGAYVAFLDISLGITSPLAGALASHYGVSSVYLAG 383 G SL+FP GVE ++R P Q RG A+G Y AF DI+LG++ PLAG LA+ +G SSV+LAG Sbjct: 315 GCSLIFPALGVEVVKRVPSQVRGTALGGYAAFQDIALGVSGPLAGMLATTFGYSSVFLAG 374 Query: 384 AVVVGLSMLVAL 395 A+ L ++V + Sbjct: 375 AISAVLGIIVTI 386 >yhhS [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 419 Score = 262 bits (670), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 161/384 (41%), Positives = 230/384 (59%), Gaps = 3/384 (0%) Query: 13 TPLASP---GTAVFLKLAPLTLAVFIAFLTIGLQLPVLPLHLKDALGMNATVVGVVVGAQ 69 P+A P G + L++ + + F ++LTIGL L VLP ++ D +G +A G+V+ Q Sbjct: 17 EPVAEPALNGLRLNLRIVSIVMFNFASYLTIGLPLAVLPGYVHDVMGFSAFWAGLVISLQ 76 Query: 70 FAAALLSRSWAGNYADLRGAKRAVLGGFTAASLSGLVYLASLAWLDHPVASVLVLLLGRL 129 + A LLSR AG YAD G K+ V+ G LSGL YL + PV S+L+L LGR+ Sbjct: 77 YFATLLSRPHAGRYADSLGPKKIVVFGLCGCFLSGLGYLTAGLTASLPVISLLLLCLGRV 136 Query: 130 LLALGESLVVTGTMSWGIALVGPQHGGKVMAWLGIAIYAAMACGAPLGVAVNHAYGFAGI 189 +L +G+S TG+ WG+ +VG H G+V++W GI Y AMA GAPLGV H G + Sbjct: 137 ILGIGQSFAGTGSTLWGVGVVGSLHIGRVISWNGIVTYGAMAMGAPLGVVFYHWGGLQAL 196 Query: 190 AGVSVLIPLLALLMLAGLPAVAPSANRRTPFYKVLGAVWQPGLGLALSSVGFGVITAFIA 249 A + + + L+A+L+ P V S + PF VLG VW G+ LAL+S GFGVI FI Sbjct: 197 ALIIMGVALVAILLAIPRPTVKASKGKPLPFRAVLGRVWLYGMALALASAGFGVIATFIT 256 Query: 250 LLFAAHAWGDSSLAFTSFGIAFIVARLLFAHLPDKVGGARVALVCVVIEVLGQLLIWQAG 309 L + A W ++ A T F AF+ RLLF + +++GG VA++C +E++G LL+ A Sbjct: 257 LFYDAKGWDGAAFALTLFSCAFVGTRLLFPNGINRIGGLNVAMICFSVEIIGLLLVGVAT 316 Query: 310 SASWAYAGAALTGFGYSLVFPGFGVEAMRRAPPQTRGLAMGAYVAFLDISLGITSPLAGA 369 A G L G G+SLVFP GV A++ P Q +G A+ Y F+D+SLG+T PLAG Sbjct: 317 MPWMAKIGVLLAGAGFSLVFPALGVVAVKAVPQQNQGAALATYTVFMDLSLGVTGPLAGL 376 Query: 370 LASHYGVSSVYLAGAVVVGLSMLV 393 + S GV +YLA A +V +++L+ Sbjct: 377 VMSWAGVPVIYLAAAGLVAIALLL 400