BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0248.p (319 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RP109 [C] COG0280 Phosphotransacetylase Rpr Rickettsia prowazekii 338 1e-92 TM1130 [C] COG0280 Phosphotransacetylase Tma Thermotoga maritima 206 5e-53 CAC3076 [C] COG0280 Phosphotransacetylase Cac Clostridium acetob... 202 9e-52 BS_yqiS [C] COG0280 Phosphotransacetylase Bsu Bacillus subtilis 195 1e-49 RC0147 [C] COG0280 Phosphotransacetylase Rco Rickettsia conorii 170 5e-42 >RP109 [C] COG0280 Phosphotransacetylase Rpr Rickettsia prowazekii Length = 351 Score = 338 bits (866), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 179/325 (55%), Positives = 233/325 (71%), Gaps = 9/325 (2%) Query: 3 PPTQATP------AERYGQLIRDAIGAQPMRVAVVHPCSVEALQGALEARDEGLLEPLLV 56 PPT+ A+ + L+ A G +P++ AVVHP E+L GA+ A +++P+L+ Sbjct: 26 PPTEIKDSDFDKAAKHFINLLLRADGLKPIKTAVVHPIDKESLLGAVRAAQFNVIKPILI 85 Query: 57 GPQAKIRHIAEQAGLSLQGLLIEDVEHSHAAAARAVELAIQGQVGALMKGSLHSDELLGA 116 GPQ KI +A+ + L+ + + EHSH AA +AVELA + +V A+MKG+LH+DEL+ A Sbjct: 86 GPQHKIESVAKVNDVDLENYQVINAEHSHEAAKKAVELAKKREVAAIMKGALHTDELMSA 145 Query: 117 VVGAGSGLRTERRISHVYAMAIPTYAKPLIITDAAINIAPTLAHKRDICQNAIDLLHVMG 176 VV +GLRTERRISH + MA+ T+ KP IITDAAINI PTL KRDI QNAIDL+H++ Sbjct: 146 VVYKENGLRTERRISHAFLMAVATFPKPFIITDAAINIRPTLEDKRDIVQNAIDLMHIIK 205 Query: 177 VPRP-HVAVLAAVETVNPAMPSTLDAAALTVMATRHQITGAMVDGPLAFDNAISLQSAAI 235 + VAVL+AVETV A+P+TLDAAAL+ MA R QIT A+VDGPLAFDNAISL +A Sbjct: 206 EDKQVRVAVLSAVETVTSAIPTTLDAAALSKMADRGQITNAVVDGPLAFDNAISLFAAEA 265 Query: 236 KDIQSPVAGSADILLVPDLEAGNMLAKQLIYLAQAEAAGLVLGARVPVILTSRADSLRVR 295 K I SPV+G+ADIL+VPDLE+GNMLAKQL YL QA AG+VLGARVP+ILTSRAD + +R Sbjct: 266 KGISSPVSGNADILVVPDLESGNMLAKQLKYLGQAVMAGIVLGARVPIILTSRADPIDMR 325 Query: 296 LASSALARLF--ASRSKLHAVGKEV 318 + S LA +++KLH K + Sbjct: 326 VISCVLASFIYNQTKAKLHNSSKSI 350 >TM1130 [C] COG0280 Phosphotransacetylase Tma Thermotoga maritima Length = 294 Score = 206 bits (524), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 114/268 (42%), Positives = 168/268 (62%), Gaps = 1/268 (0%) Query: 39 LQGALEARDEGLLEPLLVGPQAKIRHIAEQAGLSLQGLLIEDVEHSHAAAARAVELAIQG 98 ++ A E + EP+L GP+ +I I E+ + I D A AVE +G Sbjct: 28 IEAVYRAWRERVCEPVLFGPEEEITRIIEELVPEWKNPQIIDCPPEEAGRL-AVEAVSKG 86 Query: 99 QVGALMKGSLHSDELLGAVVGAGSGLRTERRISHVYAMAIPTYAKPLIITDAAINIAPTL 158 + LMKG + + +L+ + GLRT + ++ V M IP + +PLII+D + I+PTL Sbjct: 87 ECDFLMKGKIKTGDLMKIYLDERYGLRTGKTMAMVSVMEIPDFPRPLIISDPGMLISPTL 146 Query: 159 AHKRDICQNAIDLLHVMGVPRPHVAVLAAVETVNPAMPSTLDAAALTVMATRHQITGAMV 218 K D+ ++ + + +VMG+ P VAV+ A+E VNP MP T++AA L+ M R QI G +V Sbjct: 147 EQKVDMIEHCVRVANVMGLETPKVAVVGAIEVVNPKMPITMEAAILSKMNQRGQIKGCIV 206 Query: 219 DGPLAFDNAISLQSAAIKDIQSPVAGSADILLVPDLEAGNMLAKQLIYLAQAEAAGLVLG 278 DGP A DN +S ++A K IQSPVAG ADIL++PD+EA N+L K L++LA+A++A +LG Sbjct: 207 DGPFALDNVVSEEAAKKKGIQSPVAGKADILILPDIEAANILYKALVFLAKAKSASTILG 266 Query: 279 ARVPVILTSRADSLRVRLASSALARLFA 306 +VPV+LTSRADS + S AL+ +FA Sbjct: 267 GKVPVVLTSRADSEETKFYSIALSAVFA 294 >CAC3076 [C] COG0280 Phosphotransacetylase Cac Clostridium acetobutylicum Length = 301 Score = 202 bits (514), Expect = 9e-52, Method: Compositional matrix adjust. Identities = 111/299 (37%), Positives = 169/299 (56%) Query: 11 ERYGQLIRDAIGAQPMRVAVVHPCSVEALQGALEARDEGLLEPLLVGPQAKIRHIAEQAG 70 + + ++I + +VAV L+ +A+ G+ + +LVG +I IA + G Sbjct: 3 KSFNEIIMKVKSKEMKKVAVAVAQDEPVLEAVRDAKKNGIADAILVGDHDEIVSIALKIG 62 Query: 71 LSLQGLLIEDVEHSHAAAARAVELAIQGQVGALMKGSLHSDELLGAVVGAGSGLRTERRI 130 + + I + + AA +AVEL G+ +MKG +++ L +V+ GLRT + + Sbjct: 63 MDVNDFEIVNEPNVKKAALKAVELVSTGKADMVMKGLVNTATFLRSVLNKEVGLRTGKTM 122 Query: 131 SHVYAMAIPTYAKPLIITDAAINIAPTLAHKRDICQNAIDLLHVMGVPRPHVAVLAAVET 190 SHV + + L +TD A N P L K DI N++ + H +G+ P VA + AVE Sbjct: 123 SHVAVFETEKFDRLLFLTDVAFNTYPELKEKIDIVNNSVKVAHAIGIENPKVAPICAVEV 182 Query: 191 VNPAMPSTLDAAALTVMATRHQITGAMVDGPLAFDNAISLQSAAIKDIQSPVAGSADILL 250 +NP MPSTLDAA L+ M+ R QI G +VDGPLA D A+S ++A K + VAG ADI L Sbjct: 183 INPKMPSTLDAAMLSKMSDRGQIKGCVVDGPLALDIALSEEAAHHKGVTGEVAGKADIFL 242 Query: 251 VPDLEAGNMLAKQLIYLAQAEAAGLVLGARVPVILTSRADSLRVRLASSALARLFASRS 309 +P++E GN++ K L Y ++ G+++G PV+LTSRADS ++ S ALA L A Sbjct: 243 MPNIETGNVMYKTLTYTTDSKNGGILVGTSAPVVLTSRADSHETKMNSIALAALVAGNK 301 >BS_yqiS [C] COG0280 Phosphotransacetylase Bsu Bacillus subtilis Length = 299 Score = 195 bits (495), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 129/305 (42%), Positives = 172/305 (56%), Gaps = 17/305 (5%) Query: 17 IRDAIGAQPMR----VAVVHPCSVEALQGALEARDEGLLEPLLVGPQAKIRHIAEQAGLS 72 ++D IG + +AV H E ++ A + LL G K+ + S Sbjct: 3 LKDLIGKASIHKNKTIAVAHAEDEEVIRAVKLAAEHLSARFLLTGDSKKLNELTS----S 58 Query: 73 LQGLLIEDV-----EHSHAAAARAVELAIQGQVGALMKGSLHSDELLGAVVGAGSGLRTE 127 +QG +E V E S A RAV LMKG++ + LL AV+ GLR+ Sbjct: 59 MQGHQVEIVHANTPEESAKLAVRAVH---HKTADVLMKGNVPTSVLLKAVLNRQEGLRSA 115 Query: 128 RRISHVYAMAIPTYAKPLIITDAAINIAPTLAHKRDICQNAIDLLHVMGVPRPHVAVLAA 187 +SHV IP + + + +TD+A+NIAP+L R I QNA+ + H +G P A LAA Sbjct: 116 SVLSHVAVFDIPDFDRLMFVTDSAMNIAPSLEELRQILQNAVHVAHAVGNNMPKAAALAA 175 Query: 188 VETVNPAMPSTLDAAALTVMATRHQITGAMVDGPLAFDNAISLQSAAIKDIQSPVAGSAD 247 VETVNP M +T++AAAL M R QI G +VDGPLA DNA+S +AA K I VAG+ D Sbjct: 176 VETVNPKMEATVNAAALAQMYKRGQIKGCIVDGPLALDNAVSQIAAAQKKISGDVAGNPD 235 Query: 248 ILLVPDLEAGNMLAKQLIYLAQAEAAGLVLGARVPVILTSRADSLRVRLASSALARLFAS 307 ILLVP +EAGN+L K LIY A+A A ++ GA+ P+ LTSRADS +L S ALA + AS Sbjct: 236 ILLVPTIEAGNILYKSLIYFAKASVAAVITGAKAPIALTSRADSAENKLYSIALA-ICAS 294 Query: 308 RSKLH 312 H Sbjct: 295 EEYTH 299 >RC0147 [C] COG0280 Phosphotransacetylase Rco Rickettsia conorii Length = 155 Score = 170 bits (430), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 90/136 (66%), Positives = 106/136 (77%), Gaps = 1/136 (0%) Query: 136 MAIPTYAKPLIITDAAINIAPTLAHKRDICQNAIDLLHVM-GVPRPHVAVLAAVETVNPA 194 M + T+ KP IITDAAINI PTL KRDI QNAIDL+H++ + VAVL+ VETV A Sbjct: 1 MVVATFPKPFIITDAAINIRPTLEDKRDIVQNAIDLMHMIREDTQVRVAVLSVVETVTSA 60 Query: 195 MPSTLDAAALTVMATRHQITGAMVDGPLAFDNAISLQSAAIKDIQSPVAGSADILLVPDL 254 +P+TLDAAAL+ M R QIT A+VDGPLAFDNAISL +A K I S V+G+ADIL+VPDL Sbjct: 61 IPTTLDAAALSQMVDRGQITNAIVDGPLAFDNAISLFAAEAKCISSSVSGNADILVVPDL 120 Query: 255 EAGNMLAKQLIYLAQA 270 E+GNMLAKQL YL QA Sbjct: 121 ESGNMLAKQLKYLGQA 136