BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0156.p (529 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2217 [C] COG1012 NAD-dependent aldehyde dehydrogenases Pae Pse... 652 0.0 PA1253 [C] COG1012 NAD-dependent aldehyde dehydrogenases Pae Pse... 617 e-176 RSp0827 [C] COG1012 NAD-dependent aldehyde dehydrogenases Rso Ra... 464 e-130 CC2791 [C] COG1012 NAD-dependent aldehyde dehydrogenases Ccr Cau... 453 e-127 AGl3116 [C] COG1012 NAD-dependent aldehyde dehydrogenases Atu Ag... 431 e-120 >PA2217 [C] COG1012 NAD-dependent aldehyde dehydrogenases Pae Pseudomonas aeruginosa Length = 527 Score = 652 bits (1681), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/524 (63%), Positives = 403/524 (76%), Gaps = 1/524 (0%) Query: 5 ILGHNYIGGQRSGKGDIALHSVDATTGALFETPFLTATEHEVAAAVDAAEKAYPLYRAIA 64 ILGHN+IGG RS G + L S+DA +G F+ AT EV AA +AA AYP YR + Sbjct: 4 ILGHNFIGGARSAAGTLFLQSLDAASGEALPYRFVQATPEEVDAAAEAAASAYPHYRQLP 63 Query: 65 AEQRALFLEAIADEIDALGDDFLAAVSRETALPATPRLAGERARTSGQMRLFAKVVRRGD 124 A +RA FL+ IA E+DAL DDF+A V RETALPAT R+ GER+RTSGQ+RLFA+V+RRGD Sbjct: 64 ASRRAEFLDTIAAELDALDDDFVAIVCRETALPAT-RIQGERSRTSGQLRLFAEVLRRGD 122 Query: 125 FYGARIDTALPQRQPLPRPDIRQYKIGVGPVAVFGASNFPLAFSVAGGDTAAALAAGCPV 184 F+GARID A P+R+PLPR D+RQ +IG+GPVAVFGASNFPLAFS AGGDTAAALAAGCPV Sbjct: 123 FHGARIDRARPERKPLPRVDLRQCRIGLGPVAVFGASNFPLAFSTAGGDTAAALAAGCPV 182 Query: 185 VFKAHSGHLVTSELVANAIERAVKKTGMPAGTFNMIYGDRVGAQLVKSAGIQAVGFTGSL 244 VFKAHSGH+ T+E VA AI RA ++TGMPAG FNMIYG VG +LV+ IQAVGFTGSL Sbjct: 183 VFKAHSGHMATAERVAAAILRAAERTGMPAGVFNMIYGGGVGERLVRHPAIQAVGFTGSL 242 Query: 245 RGGRALCDMAAARPQPIPVFAEMSSINPIILMSEALKVRGDAIAKDLAGSVTVGVGQLCT 304 +GGRALCDMAAAR QPIPVFAEMSSINP++L+ ALK RG+A+A +L+ SV +G GQ CT Sbjct: 243 KGGRALCDMAAARAQPIPVFAEMSSINPVVLLPAALKKRGEAVADELSASVVLGCGQFCT 302 Query: 305 SPGLLLGVRSPELTAFIEKLSAAFGGSNPATMLNSGGLTHYNGGVARLTQLPGVKVIATG 364 +PGL++G+RS + +AF+E+ +A TMLN+G L Y G+A L P V+ +A Sbjct: 303 NPGLVIGIRSAQFSAFLERFAARMDDQPAQTMLNTGTLASYEKGLAALHAHPRVRHLAGQ 362 Query: 365 GTSYTQAVPHLFKADAALLFSKEAPLEEEVFGPSTVIVELESREQLLDFAAKMNGQLTAT 424 QA P LF+AD +LL + L+EEVFGP++V+VE+ +L ++GQLTAT Sbjct: 363 PQEGRQARPQLFQADVSLLLEGDELLQEEVFGPASVVVEVADHAELKRALHGLHGQLTAT 422 Query: 425 LQAEIGDLQGNQDLIAILEQKAGRLLLNGFPTGVEVCDAMVHGGPYPATSDARGTSVGTL 484 L AE DL DL+ +LEQKAGRLLLNG+PTGVEVCDAMVHGGPYPATSDARGTSVGTL Sbjct: 423 LIAEAEDLASFADLVPLLEQKAGRLLLNGYPTGVEVCDAMVHGGPYPATSDARGTSVGTL 482 Query: 485 AIERFLRPVCYQNYPDAMLPAPLQNANPLGLMRLVDGEQTRATV 528 AI+RFLRPVCYQNYPDA LP L++ NPLG+ RLVDG TRA V Sbjct: 483 AIDRFLRPVCYQNYPDAWLPEALKDGNPLGIARLVDGIVTRAAV 526 >PA1253 [C] COG1012 NAD-dependent aldehyde dehydrogenases Pae Pseudomonas aeruginosa Length = 526 Score = 617 bits (1590), Expect = e-176, Method: Compositional matrix adjust. Identities = 325/522 (62%), Positives = 394/522 (75%), Gaps = 2/522 (0%) Query: 4 KILGHNYIGGQRSGKGDIALHSVDATTGALFETPFLTATEHEVAAAVDAAEKAYPLYRAI 63 ILGHNY+GG RS G++ L S+DA +G F+ ATE EV AA AAE+AYP YR + Sbjct: 3 SILGHNYVGGARSAAGNLTLRSLDADSGEALPYAFVQATEAEVDAAARAAERAYPHYRQL 62 Query: 64 AAEQRALFLEAIADEIDALGDDFLAAVSRETALPATPRLAGERARTSGQMRLFAKVVRRG 123 +A +RA FLEAIA +DALGDDF+A V RETALPA R+ GER RT+ Q+RLFA+V+RRG Sbjct: 63 SATRRAGFLEAIASRLDALGDDFVALVRRETALPAA-RIEGERTRTANQLRLFAEVLRRG 121 Query: 124 DFYGARIDTALPQRQPLPRPDIRQYKIGVGPVAVFGASNFPLAFSVAGGDTAAALAAGCP 183 DF+G RID P R P PRPD+RQ++IG+GPVAVFGASNFPLAFS AGGD+AAALAAGCP Sbjct: 122 DFHGVRIDRGQPGRTP-PRPDLRQWRIGLGPVAVFGASNFPLAFSTAGGDSAAALAAGCP 180 Query: 184 VVFKAHSGHLVTSELVANAIERAVKKTGMPAGTFNMIYGDRVGAQLVKSAGIQAVGFTGS 243 VV KAH GH+ T+E VA+AI +A +GMP G FNM+YG VG LV+ I+AVGFTGS Sbjct: 181 VVVKAHGGHMATAECVADAILQAAADSGMPDGVFNMVYGSGVGEALVRHPAIRAVGFTGS 240 Query: 244 LRGGRALCDMAAARPQPIPVFAEMSSINPIILMSEALKVRGDAIAKDLAGSVTVGVGQLC 303 L+GGRALCD+AAARPQPIPVFAEMSSINP++++ EAL+ RG +A++LA SVT+G GQ C Sbjct: 241 LKGGRALCDLAAARPQPIPVFAEMSSINPLVVLPEALRRRGRQVAEELAASVTLGCGQFC 300 Query: 304 TSPGLLLGVRSPELTAFIEKLSAAFGGSNPATMLNSGGLTHYNGGVARLTQLPGVKVIAT 363 T PGL+LG+RSP AF+ L A +MLN+G L Y G+ RL + PG++ +A Sbjct: 301 TKPGLVLGLRSPGFDAFVAALGEALAARPAQSMLNAGTLRSYVEGLQRLERHPGIRRLAG 360 Query: 364 GGTSYTQAVPHLFKADAALLFSKEAPLEEEVFGPSTVIVELESREQLLDFAAKMNGQLTA 423 QA P LFKAD LL + L+EEVFGP+TV+VE EQL ++GQL+A Sbjct: 361 APQEGRQAHPQLFKADVGLLLEGDELLQEEVFGPATVVVEAADEEQLARALDNLHGQLSA 420 Query: 424 TLQAEIGDLQGNQDLIAILEQKAGRLLLNGFPTGVEVCDAMVHGGPYPATSDARGTSVGT 483 TL E DL L+ +LE+KAGRLL NG+PTGVEVCDAMVHGGPYPATSDARGTSVGT Sbjct: 421 TLIGEADDLAAFAGLVPLLERKAGRLLFNGYPTGVEVCDAMVHGGPYPATSDARGTSVGT 480 Query: 484 LAIERFLRPVCYQNYPDAMLPAPLQNANPLGLMRLVDGEQTR 525 LAIERFLRP+CYQ+YPD++LP L+NANPLGL+RLVDG TR Sbjct: 481 LAIERFLRPLCYQDYPDSLLPDALKNANPLGLLRLVDGRSTR 522 >RSp0827 [C] COG1012 NAD-dependent aldehyde dehydrogenases Rso Ralstonia solanacearum Length = 528 Score = 464 bits (1193), Expect = e-130, Method: Compositional matrix adjust. Identities = 264/505 (52%), Positives = 335/505 (66%), Gaps = 5/505 (0%) Query: 23 LHSVDATTGALFETPFLTATEHEVAAAVDAAEKAYPLYRAIAAEQRALFLEAIADEIDAL 82 + +++ TG + F A+ +VA A + A A+ +YR A E RALFLEAIA +I+ L Sbjct: 21 VRAMNPATGEWLDPQFTLASRADVARACELAGAAFDVYRETAPEARALFLEAIASQIEVL 80 Query: 83 GDDFLAAVSRETALPATPRLAGERARTSGQMRLFAKVVRRGDFYGARIDTALPQRQPLPR 142 GD + E+ALP PRL GER RT Q+RLFAKVVR GD GARID ALP+R+PLPR Sbjct: 81 GDVLIERAMAESALP-RPRLEGERGRTCNQLRLFAKVVRAGDAVGARIDPALPERKPLPR 139 Query: 143 PDIRQYKIGVGPVAVFGASNFPLAFSVAGGDTAAALAAGCPVVFKAHSGHLVTSELVANA 202 D+R +I +GPVAVFGASNFPLAFSVAGGDTA+ALAAGCPVV KAH H TSELV A Sbjct: 140 SDLRMRRIAMGPVAVFGASNFPLAFSVAGGDTASALAAGCPVVVKAHPAHPGTSELVGRA 199 Query: 203 IERAVKKTGMPAGTFNMIYGDRVGA-QLVKSAGIQAVGFTGSLRGGRALCDMAAARPQPI 261 I+ AV + G+P G F+++ D A LV IQAVGFTGS GG+AL +A AR QPI Sbjct: 200 IQAAVAQCGLPEGVFSLVLADNEAAGALVADPRIQAVGFTGSRAGGQALLRIAQARAQPI 259 Query: 262 PVFAEMSSINPIILMSEALKVRGDAIAKDLAGSVTVGVGQLCTSPGLLLGVRSPELTAFI 321 PV+ E+S+INP+ L+ +AL R A+ + GS+T+G GQ CT+PGLLL + P+L AF Sbjct: 260 PVYGELSAINPVFLLPDALARRAAALGQQYVGSLTMGAGQFCTNPGLLLAIDGPDLDAFE 319 Query: 322 EKLSAAFGGSNPATMLNSGGLTHYNGGVARLTQLPGVKVIATGGTSY--TQAVPHLFKAD 379 + A S TML+SG Y+ GV RL V+ +A G S + F+ D Sbjct: 320 AAAAEALQASAAQTMLSSGIHAAYSRGVERLAGEANVRCVARGQGSDAPNRGQAGFFRTD 379 Query: 380 AALLFSKEAPLEEEVFGPSTVIVELESREQLLDFAAKMNGQLTATLQAEIGDLQGNQDLI 439 A F + L +E+FG + ++V + E+L A + GQLTATL + GD + L+ Sbjct: 380 AE-SFRAQPALHDEIFGATGLVVRCRNAEELKALAESLEGQLTATLHLDAGDTALARALL 438 Query: 440 AILEQKAGRLLLNGFPTGVEVCDAMVHGGPYPATSDARGTSVGTLAIERFLRPVCYQNYP 499 +ILE+KAGR+L NG+PTGVEVC AMVHGGP+PAT+D R TSVGT AIERFLRPVCYQ+ P Sbjct: 439 SILERKAGRILANGWPTGVEVCHAMVHGGPWPATTDTRTTSVGTAAIERFLRPVCYQDLP 498 Query: 500 DAMLPAPLQNANPLGLMRLVDGEQT 524 +LPA L++ NP L RLVDG T Sbjct: 499 AELLPAALRDDNPQQLRRLVDGAWT 523 >CC2791 [C] COG1012 NAD-dependent aldehyde dehydrogenases Ccr Caulobacter vibrioides Length = 528 Score = 453 bits (1165), Expect = e-127, Method: Compositional matrix adjust. Identities = 264/525 (50%), Positives = 329/525 (62%), Gaps = 11/525 (2%) Query: 4 KILGHNYIGGQRSGKGDIALHSVDATTGALFETPFLTATEHEVAAAVDAAEKAYPLYRAI 63 + G IGG+R + V+ TG E F AT +V AA A +A+ YR++ Sbjct: 3 HLTGELLIGGERRFGIHGEIKGVNPATGETLEPAFGGATTADVEAACALAAEAFGPYRSL 62 Query: 64 AAEQRALFLEAIADEIDALGDDFLAAVSRETALPATPRLAGERARTSGQMRLFAKVVRRG 123 E RA FLE+IA+ I+A+GDD + ET LP PRL GER RT GQ+RLFA V+R G Sbjct: 63 PYETRAQFLESIAEHIEAIGDDLIVRTMAETGLP-RPRLEGERGRTVGQLRLFAGVLRDG 121 Query: 124 DFYGARIDTALPQRQPLPRPDIRQYKIGVGPVAVFGASNFPLAFSVAGGDTAAALAAGCP 183 F ARID A+P R+PLPRPD+R + +GPVAVFGASNFPLAFSVAGGDTA+ALAAGCP Sbjct: 122 GFLEARIDPAMPDRKPLPRPDLRLRNVPLGPVAVFGASNFPLAFSVAGGDTASALAAGCP 181 Query: 184 VVFKAHSGHLVTSELVANAIERAVKKTGMPAGTFNMIY--GDRVGAQLVKSAGIQAVGFT 241 V+ KAH H SELV AI+ AV G+P G F +I+ G V LV ++A GFT Sbjct: 182 VIVKAHPAHPGASELVGRAIQAAVAACGLPPGVFALIHDSGYEVSQALVADPRVKAAGFT 241 Query: 242 GSLRGGRALCDMAAARPQPIPVFAEMSSINPIILMSEALKVRGDAIAKDLAGSVTVGVGQ 301 GS RGG AL +A RP+PIP +AEMSSINP+IL+ ALK R D IA D ++T+G GQ Sbjct: 242 GSRRGGLALLAIAQGRPEPIPFYAEMSSINPVILLPAALKARADKIAPDFVAALTLGAGQ 301 Query: 302 LCTSPGLLLGVRSPELTAFIEKLSAAFGGSNPATMLNSGGLTHYNGGVARLTQLPGVKVI 361 CT+PGL+L + PEL AFIE A + + ML G + GVA LT V + Sbjct: 302 FCTNPGLILAIDGPELDAFIEAAGKAVEAAPASVMLTPGICQAFAHGVAALTDAAEVTTV 361 Query: 362 ATG-----GTSYTQAVPHLFKADAALLFSKEAPLEEEVFGPSTVIVELESREQLLDFAAK 416 A G G+ +A LF AA + L EEVFG ++++V + +L A Sbjct: 362 ARGVPGPDGSHTGRAA--LFSVTAADFLANPH-LHEEVFGAASLVVRCAGQAELEAVIAA 418 Query: 417 MNGQLTATLQAEIGDLQGNQDLIAILEQKAGRLLLNGFPTGVEVCDAMVHGGPYPATSDA 476 + GQLT L + D L+ LE KAGR+L+NGF TGVEV AMVHGGP+P+TSD Sbjct: 419 LEGQLTIALHMDEADHGIAGALLPALELKAGRILVNGFGTGVEVAPAMVHGGPFPSTSDG 478 Query: 477 RGTSVGTLAIERFLRPVCYQNYPDAMLPAPLQNANPLGLMRLVDG 521 R TSVGTLAI RFLRPV YQN P+A+LPA L+ NPLG++R VDG Sbjct: 479 RTTSVGTLAIARFLRPVSYQNLPEALLPAELKTQNPLGVVRRVDG 523 >AGl3116 [C] COG1012 NAD-dependent aldehyde dehydrogenases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 534 Score = 431 bits (1109), Expect = e-120, Method: Compositional matrix adjust. Identities = 234/451 (51%), Positives = 297/451 (65%), Gaps = 5/451 (1%) Query: 60 YRAIAAEQRALFLEAIADEIDALGDDFLAAVSRETALPATPRLAGERARTSGQMRLFAKV 119 Y E+RA FL+ IADEI+A D S ET LPA RL GER RT GQ+ LFA Sbjct: 87 YGYTTREERAAFLDTIADEIEARADAITEIGSSETGLPAG-RLQGERGRTVGQLHLFASH 145 Query: 120 VRRGDFYGARIDTALPQRQPLPRPDIRQYKIGVGPVAVFGASNFPLAFSVAGGDTAAALA 179 +R+GD+ R D ALP RQPLPRPDIR + +GPVAVFGASNFPLAFS AGGDTAAALA Sbjct: 146 IRKGDYLDRRHDEALPDRQPLPRPDIRLMQRPIGPVAVFGASNFPLAFSTAGGDTAAALA 205 Query: 180 AGCPVVFKAHSGHLVTSELVANAIERAVKKTGMPAGTFNMIYGDR--VGAQLVKSAGIQA 237 AGCPVV K HS H T E+VA A+ AVKK + G F++I G R VG+ LV+ I+A Sbjct: 206 AGCPVVVKGHSAHPGTGEIVAEAVLAAVKKHNLHPGVFSLIQGGRRDVGSALVQHPRIKA 265 Query: 238 VGFTGSLRGGRALCDMAAARPQPIPVFAEMSSINPIILMSEALKVRGDAIAKDLAGSVTV 297 VGFTGSL GGRAL D+ A RP+PIP F E+ S+NP+ L+ EA+ RG+AIAK AGS+T+ Sbjct: 266 VGFTGSLAGGRALFDLCAQRPEPIPFFGELGSVNPMFLLPEAVAARGEAIAKGWAGSLTM 325 Query: 298 GVGQLCTSPGLLLGVRSPELTAFIEKLSAAFGGSNPATMLNSGGLTHYNGGVARLTQLPG 357 G GQ CT+PG+ + + S + A E AA P ML G Y G R+ G Sbjct: 326 GAGQFCTNPGIAV-ILSEQADAVAETARAALSEVGPQVMLTDGIAAAYRDGRDRIAAGNG 384 Query: 358 VKVIATGGTSYTQAVPHLFKADAALLFSKEAPLEEEVFGPSTVIVELESREQLLDFAAKM 417 V+ + T + A P+L++ + A L EEVFGP +IV ++S E++L+ A Sbjct: 385 VRDVLTTTCNLRNATPYLYRVAGKDWVANHA-LAEEVFGPLGLIVTVDSAEEMLEVAKSF 443 Query: 418 NGQLTATLQAEIGDLQGNQDLIAILEQKAGRLLLNGFPTGVEVCDAMVHGGPYPATSDAR 477 GQLTAT+ + GD + + L+ ILE+KAGR+L NGFPTGVEV +AMVHGGPYPA+++ Sbjct: 444 EGQLTATMHLDAGDAELGRKLLPILERKAGRVLANGFPTGVEVSEAMVHGGPYPASTNFG 503 Query: 478 GTSVGTLAIERFLRPVCYQNYPDAMLPAPLQ 508 TSVGT++I RF+RPV YQN P +LP ++ Sbjct: 504 ATSVGTMSIRRFMRPVSYQNIPSDVLPEDIR 534