BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0046.p (418 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0078 [GEPR] COG0477 Permeases of the major facilitator superf... 265 2e-70 CAC3482 [GEPR] COG0477 Permeases of the major facilitator superf... 253 4e-67 mll3464 [GEPR] COG0477 Permeases of the major facilitator superf... 223 5e-58 YPO3263 [GEPR] COG0477 Permeases of the major facilitator superf... 221 2e-57 CAC0560 [GEPR] COG0477 Permeases of the major facilitator superf... 220 4e-57 >RSp0078 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 399 Score = 265 bits (677), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 187/399 (46%), Positives = 253/399 (63%), Gaps = 13/399 (3%) Query: 14 AAPAAATHAASHSHGLSTGLIGLLASGAGLAVASLYYSQPMLGVLADDIGASERAVGMVP 73 AAPA+ T +A+ + GLI LL +GAG++VA +Y + P+LG++ D+ + A+G++P Sbjct: 3 AAPASPTQSATTD---TQGLIRLLTAGAGVSVACIYLNHPLLGLIGHDLNIAPHALGVLP 59 Query: 74 MSTQLGYALGILLLAPLGDRYDRRRIILIKAAILTVALLLAGAASGVSTLLAASLAIGLT 133 T GYA GI PLGDRYDRR +IL KA +LT+AL+ + A G+ L AA IGL Sbjct: 60 TLTAAGYASGIFFFGPLGDRYDRRVVILWKAVLLTLALIGSCIAPGLPVLAAAGFVIGLA 119 Query: 134 ATLAQDIVPAAATLAPEQHRGRIVGTVMTGLLLGILLSRVVSGFVAEHFGWRAMFVGASA 193 AT+AQD VP+AA ++ + +R R +GTVMTGLL+GI+ SRV SG VA+HFGWRA F G SA Sbjct: 120 ATIAQDFVPSAAAISTDLNRNRNIGTVMTGLLIGIVGSRVFSGIVADHFGWRAAF-GVSA 178 Query: 194 SIALIGLAAWRGLPRF--HPTTHLSYGALLGSLGSLVKKHGALRRAALAQGLLSVGFSAF 251 + A++GLA F P T Y LL SLG+L +H LR +A Q L+V FS F Sbjct: 179 A-AIVGLALAVRAAHFGVAPATRQPYVTLLRSLGTLFARHPRLRASAFTQAFLAVAFSGF 237 Query: 252 WSTLAVMLHGAPFHLGSAAAGAFGLAGAAGALAAPLAGRISDKKGPELVTRLGVSLAALS 311 WST+A+ L G L + AG GLAGAAGAL A +AGR+S + P + G L A + Sbjct: 238 WSTVALHLTGT-IGLSAGQAGLLGLAGAAGALGASIAGRLSGRVAPGHIVAGGALLMAAT 296 Query: 312 FASMALSPWFSTQGQLVLLALAAIGFDLGVQATLVAHQTIVYSIEPGARSRLNAVLFVGM 371 FA+MAL P L + + + FD+GVQA LV+HQTI+Y++ P ARSR+NAV M Sbjct: 297 FAAMALFPH-----SLPAIVIGTLLFDVGVQAALVSHQTIIYALAPEARSRINAVFMTIM 351 Query: 372 FIGMAAGAALGSLALAQWGWIAVVGLAVISAVLALVVRL 410 FIGM+AGA SLA + W ++ ++ + L +RL Sbjct: 352 FIGMSAGAYGASLAWSYAHWTGLMAFCTAASSIGLGLRL 390 >CAC3482 [GEPR] COG0477 Permeases of the major facilitator superfamily Cac Clostridium acetobutylicum Length = 394 Score = 253 bits (647), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 141/380 (37%), Positives = 227/380 (59%), Gaps = 5/380 (1%) Query: 29 LSTGLIGLLASGAGLAVASLYYSQPMLGVLADDIGASERAVGMVPMSTQLGYALGILLLA 88 L+ LI +++ GL VA+LYY QP+L ++ SE +VG M TQ+GYA+G++L+ Sbjct: 15 LNKLLIMVMSIACGLTVANLYYIQPLLADISKTFNVSEISVGSAAMLTQIGYAVGMVLIL 74 Query: 89 PLGDRYDRRRIILIKAAILTVALLLAGAASGVSTLLAASLAIGLTATLAQDIVPAAATLA 148 PLGD +RR +I ++L +S + L +S A+G T+ + Q I+P AA L+ Sbjct: 75 PLGDIKERRNLITTILLFSVISLASMFFSSNIYILTISSFAVGFTSIIPQLIIPLAAQLS 134 Query: 149 PEQHRGRIVGTVMTGLLLGILLSRVVSGFVAEHFGWRAMFVGASASIALIGLAAWRGLPR 208 ++ RGRI+GTVM+GLL+GIL+SR SG + ++GWR +++ A+ + + +A + LP Sbjct: 135 NQKDRGRIIGTVMSGLLIGILVSRTFSGILGAYWGWRVVYIIAAIMMIFLMIALRKLLPV 194 Query: 209 FHPTTHLSYGALLGSLGSLVKKHGALRRAALAQGLLSVGFSAFWSTLAVMLHGAPFHLGS 268 P++++ Y LL S+ L+K LR A++ ++ FSAFW++L +L +++GS Sbjct: 195 SKPSSNVKYIELLKSMFQLIKSEPVLREASINGAMMFAAFSAFWTSLTFLLQSPHYNMGS 254 Query: 269 AAAGAFGLAGAAGALAAPLAGRISDKKGPELVTRLGVSLAALSFASMALSPWFSTQGQLV 328 AAG FGL G +GALAAPL GRI+DKKGP + + + + +S+ + L F G Sbjct: 255 QAAGLFGLVGVSGALAAPLVGRIADKKGPRFIIGICIPIITISYL-LFLLLGFKIFG--- 310 Query: 329 LLALAAIGFDLGVQATLVAHQTIVYSIEPGARSRLNAVLFVGMFIGMAAGAALGSLALAQ 388 L L + DLGVQ+ V++QT V+S+ R+R+N V V F+G A G+ +GS Sbjct: 311 -LILGVMLLDLGVQSGNVSNQTRVHSLNEKMRNRINTVYMVSFFLGGAFGSFMGSFTYVH 369 Query: 389 WGWIAVVGLAVISAVLALVV 408 +GW V + + ++ ++ Sbjct: 370 FGWYGVCIFGISTQIITFII 389 >mll3464 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 405 Score = 223 bits (569), Expect = 5e-58, Method: Compositional matrix adjust. Identities = 151/388 (38%), Positives = 220/388 (56%), Gaps = 3/388 (0%) Query: 19 ATHAASHSHGLSTGLIGLLASGAGLAVASLYYSQPMLGVLADDIGASERAVGMVPMSTQL 78 A+ +AS +S + LLA+ GL VA++YY+QP++G + ++G A G++ Q+ Sbjct: 6 ASGSASAETTISNWMTFLLAAACGLIVANIYYAQPLIGPIGAELGLPPHAAGLIVTMAQI 65 Query: 79 GYALGILLLAPLGDRYDRRRIILIKAAILTVALLLAGAASGVSTLLAASLAIGLTATLAQ 138 GY +G+L + PLGD + RR++L A+ T+ALL A ++ + LAA L +GL + Q Sbjct: 66 GYGVGLLFIVPLGDLIENRRLVLGILAVATLALLGAAISTQPAFFLAAMLFVGLGSVAVQ 125 Query: 139 DIVPAAATLAPEQHRGRIVGTVMTGLLLGILLSRVVSGFVAEHFGWRAMFVGASASIALI 198 ++P AA LAPE RGR+VG V GLLLGI+LSR S F+ W ++ + A + L+ Sbjct: 126 TLIPYAAHLAPEARRGRVVGNVSVGLLLGIMLSRPFSSFITALSSWHVVYFTSCAVMILL 185 Query: 199 GLAAWRGLPRFHPTTHLSYGALLGSLGSLVKKHGALRRAALAQGLLSVGFSAFWSTLAVM 258 + LPR PT LSYGALL S+ + + LRR AL Q L FS FW+T ++ Sbjct: 186 TVVLRFALPRRVPTARLSYGALLASMVQIARSTPVLRRRALYQAFLFAAFSLFWTTTPLL 245 Query: 259 LHGAPFHLGSAAAGAFGLAGAAGALAAPLAGRISDKKGPELVTRLGVSLAALSFASMALS 318 L G F L G F LAG AGA+AAPLAGR++D+ T + A++F ++ Sbjct: 246 LAGPDFGLTQRGIGLFALAGVAGAIAAPLAGRVADRGWSRPATAFAMLCVAVAFLVTHIA 305 Query: 319 PWFSTQGQLVLLALAAIGFDLGVQATLVAHQTIVYSIEPGARSRLNAVLFVGMFIGMAAG 378 P ST +L+A A + D GVQ LV ++++ RSRLN + FI A G Sbjct: 306 PSGSTLSLALLVAAAIVL-DFGVQTNLVLGYRDLFALGAAHRSRLNGLYMATFFIAGAIG 364 Query: 379 AALGSLALAQWGW--IAVVGLAVISAVL 404 + +G A AQ GW ++ +GLA+ A L Sbjct: 365 SGVGGWAYAQDGWPLVSWIGLALPVAAL 392 >YPO3263 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 399 Score = 221 bits (564), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 147/387 (37%), Positives = 220/387 (56%), Gaps = 5/387 (1%) Query: 24 SHSHGLSTGLIGLLASGAGLAVASLYYSQPMLGVLADDIGASERAVGMVPMSTQLGYALG 83 + + GLS LI L++ GLAVAS YY+QP+L +A + S G + + QLGYA+G Sbjct: 4 TDTPGLSPALIVLMSVATGLAVASNYYAQPLLETIATNFNLSVNQAGFIVTAAQLGYAVG 63 Query: 84 ILLLAPLGDRYDRRRIILIKAAILTVALLLAGAASGVSTLLAASLAIGLTATLAQDIVPA 143 ++ L PLGD ++RR +I+ + +L+ + ++ ++ + GL + +AQ +VP Sbjct: 64 LMFLVPLGDMFERRGLIVGMTLLAAGGMLITAMSQNLTMMIIGTALTGLFSVVAQLLVPL 123 Query: 144 AATLAPEQHRGRIVGTVMTGLLLGILLSRVVSGFVAEHFGWRAMFVGASASIALIGLAAW 203 AATLA + RG++VG +M+GLLLGILL+R V+G +A GWR ++ ASA + ++ L W Sbjct: 124 AATLAAPEKRGKVVGIIMSGLLLGILLARTVAGALATLGGWRTIYWVASALMFIMALVLW 183 Query: 204 RGLPRFHPTTHLSYGALLGSLGSLVKKHGALRRAALAQGLLSVGFSAFWSTLAVMLHGAP 263 R LPR+ T L+YG LLGS+ +L LR AL L FS W+++A +L P Sbjct: 184 RCLPRYKQHTGLNYGQLLGSIFALFIHTPVLRTRALLGALSFANFSVLWTSMAFLLAAPP 243 Query: 264 FHLGSAAAGAFGLAGAAGALAAPLAGRISDKKGPELVTRLGVSLAALSFASMALSPWFST 323 F A G FGL GAAGAL A AG+++DK + T G+ L LS+ +A Sbjct: 244 FGYSEATIGLFGLVGAAGALMATKAGQLADKGKARVTTSAGLVLLLLSWLPIAFG----- 298 Query: 324 QGQLVLLALAAIGFDLGVQATLVAHQTIVYSIEPGARSRLNAVLFVGMFIGMAAGAALGS 383 Q ++ L + I DL VQA V +Q+++Y + P AR+RL A FIG A G+ + + Sbjct: 299 QHSIIALIIGIIVLDLAVQAVHVTNQSVMYRMMPEARNRLTAGYMTSYFIGGALGSLISA 358 Query: 384 LALAQWGWIAVVGLAVISAVLALVVRL 410 A GW V ++ +L +V L Sbjct: 359 AAYQHAGWYGVSTAGLVLCLLNIVTWL 385 >CAC0560 [GEPR] COG0477 Permeases of the major facilitator superfamily Cac Clostridium acetobutylicum Length = 441 Score = 220 bits (561), Expect = 4e-57, Method: Compositional matrix adjust. Identities = 136/384 (35%), Positives = 216/384 (56%), Gaps = 5/384 (1%) Query: 24 SHSHGLSTGLIGLLASGAGLAVASLYYSQPMLGVLADDIGASERAVGMVPMSTQLGYALG 83 S L+ +I ++A + VA+LYY QP+LG +A +E G V TQ+GYALG Sbjct: 43 KESFELNKFIIFIMALTCTVTVANLYYCQPLLGQIAKSFNVTEANAGFVVTLTQVGYALG 102 Query: 84 ILLLAPLGDRYDRRRIILIKAAILTVALLLAGAASGVSTLLAASLAIGLTATLAQDIVPA 143 +L L PLGD +R+++I+ +++V L A + LL S IG T + Q IVP Sbjct: 103 MLFLVPLGDIKERKKLIIEMLLLVSVFLFAAFISRNYYVLLVTSFLIGFTTIVPQLIVPF 162 Query: 144 AATLAPEQHRGRIVGTVMTGLLLGILLSRVVSGFVAEHFGWRAMFVGASASIALIGLAAW 203 AA L+ + RG+++G V++GLL+GILLSRV SG + + GWR +++ AS + Sbjct: 163 AAHLSKPEERGQVIGNVLSGLLIGILLSRVFSGIIGDILGWRNVYLIASLLMVSFLFIIV 222 Query: 204 RGLPRFHPTTHLSYGALLGSLGSLVKKHGALRRAALAQGLLSVGFSAFWSTLAVMLHGAP 263 P+ PT+ +SY L+ S+ L+K+ LR A++ L+ FS FW+ L +L Sbjct: 223 FLFPKSKPTSKISYKKLIFSMWGLIKREKVLREASINGALMFGSFSIFWTALVFLLESKV 282 Query: 264 FHLGSAAAGAFGLAGAAGALAAPLAGRISDKKGPELVTRLGVSLAALSFASMALSPWFST 323 +++GS AG FGL G GALAAP+ G+++DKK P R V A + F+++A ++ Sbjct: 283 YNMGSKEAGFFGLVGIVGALAAPVVGKVADKKTP----RFAVGFAII-FSTIAYVCFWGM 337 Query: 324 QGQLVLLALAAIGFDLGVQATLVAHQTIVYSIEPGARSRLNAVLFVGMFIGMAAGAALGS 383 ++ L + I DLG Q V++Q V +I RSR+N V V FIG + G+ + + Sbjct: 338 GYKIYGLVIGVILLDLGNQTGQVSNQARVQAISDQERSRINTVFMVSYFIGGSIGSFVAA 397 Query: 384 LALAQWGWIAVVGLAVISAVLALV 407 + ++GW V + + ++A++ Sbjct: 398 VFWQKFGWSGVCAIGMFFQIIAVI 421