BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0029.p (1093 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEII0449 [V] COG0610 Type I site-specific restriction-modificat... 343 1e-93 jhp1424 [V] COG0610 Type I site-specific restriction-modificatio... 320 9e-87 HP1402 [V] COG0610 Type I site-specific restriction-modification... 307 9e-83 XF2739 [V] COG0610 Type I site-specific restriction-modification... 274 9e-73 MJECL40 [V] COG0610 Type I site-specific restriction-modificatio... 274 1e-72 >BMEII0449 [V] COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Bme Brucella melitensis Length = 783 Score = 343 bits (880), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 249/741 (33%), Positives = 368/741 (49%), Gaps = 83/741 (11%) Query: 79 QVQAVNLTEGLLPANERVYQMLTLGVTVTEFMPDGKKHQPTIALVDWHDPTANRWDVTEE 138 +V AV++ E ANE Y LT GVT G++ + D+ DP+AN ++ + Sbjct: 77 RVTAVDVME----ANESAYTALTYGVTAPH-TEGGRRQDRNVRFFDFDDPSANTFEFARQ 131 Query: 139 LEVLSTHGTHHRVPDVVAYVNGLPLVVIEAKRPD-ASHMGQAMVEEGISQQLRNQRPDEI 197 + + +PD+V YVNGLPL IE K P A MG+A I Q R + DE Sbjct: 132 VAIKGAR--QDIIPDIVVYVNGLPLAAIECKSPSLADPMGEA-----IRQFRRYENRDEF 184 Query: 198 A-----QLFAYAQLLLAVSPTEARYGTTSTPMKFWARWREEQFSDAQLHEWKNLPLSTDA 252 A +LF AQ+ +A++ A+YGTT TP + WA W++ PL+ DA Sbjct: 185 AGLGAPRLFETAQISIALARDVAKYGTTLTPARQWAEWKDP------------YPLTLDA 232 Query: 253 EAALLAGKPSKLQSYFRQLWTQPLLPNEQDRLLAALLHPQRLLEYLRLFVLFDRKAG--- 309 AA L P+ QD LLA LL P LL+ +R FV+F+ G Sbjct: 233 LAAQLGRTPTG-----------------QDILLAGLLAPANLLDLIRNFVVFETIGGRRI 275 Query: 310 KVVARYQQFFGIRALLERINQRKPDGGREGGVVWHTTGSGKSFTMVFLTKALVLHQSTQV 369 K +ARYQQF + +ERI + P+ R GGV+ HT GSGKS TMVFL L + Sbjct: 276 KKLARYQQFVAVGKAIERI-RTAPNPQRRGGVIHHTQGSGKSLTMVFLATKLRRLPEAEN 334 Query: 370 CRVLVVTDRLDLEDQLARNFMNSGAFGSAVATKKDGEKAKVGSGRELAKRIGQGSERIIF 429 +++VTDR DL+DQ+ F SG F + + + SG L K + G+ + Sbjct: 335 PTIVIVTDRTDLDDQITGQFQRSG-FANPMQAE---------SGDSLRKALSGGAGTTVL 384 Query: 430 TLLQKFATA-SKLSECYNPSADMIVLVDEGHRSHGGETHERMRKALPRAAYVAFTGTPLL 488 T + KF +A K S + + ++ V+VDE HR+ G RMR LP A +AFTGTP+ Sbjct: 385 TTVHKFHSAVPKRSSVISKARNVFVMVDEAHRTQYGALAARMRAGLPNACMIAFTGTPID 444 Query: 489 KKDK-TANKFGSIVHAYTMQRAVEDGTVAPLLYEERVPELTINEEAVNRWFDRITAGLSP 547 KKD+ T FG +H Y + +AV+DG P+ YE R + I+ R LS Sbjct: 445 KKDRSTREAFGDYLHRYLIDQAVKDGATVPIYYEMRDARIRIDGRDFEREVRAAFPELSE 504 Query: 548 EQAADLKRKFANKQAVYGAANRIELIAWDIAQHFNENIKKLGQGLKGQVATASKLEAIRY 607 ++ A L+R ++ + GA R+E IA DI H+ I+ G K Q+ T S+ A+ Y Sbjct: 505 DEIAKLRRGTGLQEKLAGAPVRVEAIAQDILSHYRSTIEP--NGFKAQIVTVSRDVAVTY 562 Query: 608 KQYLDDTGLVSSAVIISAPDSREGNTEVDESKLPEVQKWWNSHVGKNAEGYEQQVLQDFG 667 + L+ G A+I+SA ++ D ++L H+ K + + F Sbjct: 563 VEALERLGAPECALIMSASNN-------DSARL------QARHLSKRDRDSK---ISRFK 606 Query: 668 SDGEP-DLLIVVDRLLTGFDEPRNTVLYIDKPLKEHSLIQAVARVNRLHEAKRYGVLVDY 726 +P +L+V D LLTGFD P VLY+D PL+EH+L+QA+ARVNR + K YG++VDY Sbjct: 607 KRDDPLKILVVCDMLLTGFDAPIEQVLYLDAPLREHTLLQAIARVNRTADGKTYGLVVDY 666 Query: 727 RGILKELDTAVRAYQDLENRTQGGYELAD-IEGLYQQMSTEYKRLPGLHDELWEIFAEVQ 785 G + + A+ + D + L++ I+ L + + G+ + E+ Sbjct: 667 WGDNRRIADALDMFSDEDGIASALRPLSEKIQLLESRHRAAIRLFEGISHQNDTACVELL 726 Query: 786 NKQDLEQYRQLLMPRYAEDED 806 + D+ +L R+AE D Sbjct: 727 RQDDIRAKFELDFLRFAEAMD 747 >jhp1424 [V] COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases jHp Helicobacter pylori J99 Length = 991 Score = 320 bits (821), Expect = 9e-87, Method: Compositional matrix adjust. Identities = 299/1035 (28%), Positives = 483/1035 (46%), Gaps = 168/1035 (16%) Query: 85 LTEGLLPANERVYQMLTLGVTVTEFMPDGKKHQPTIALVDWHDPTANRWDVTEELEVLST 144 L L AN++ Y++L GV + + + T L+DW D + N + V EE+ S Sbjct: 65 LKNDLYEANQKFYELLIYGVKTKISLNENTQ---THWLIDWKDVSKNEFSVAEEV---SA 118 Query: 145 HGTHHRVPDVVAYVNGLPLVVIEAKRPDASHMGQAMVEEGISQQLRNQRPDEIAQLFAYA 204 G + + PD+V YVNG+ L V+E K+ S VE GI Q L NQ+ + I F Sbjct: 119 KGPNMKRPDIVLYVNGIALGVLELKKSSVS------VESGIRQNLDNQKKEFIRDFFKTI 172 Query: 205 QLLLAVSPTEA-RYGTTSTPMKFWARWREEQFSDAQLHEWKNLPLSTDAEAALLAGKPSK 263 QL++A + ++ +YG T K++ W+EE KNL Sbjct: 173 QLVMAGNESQGLKYGVIETEEKYYLSWKEEGVQ-------KNLF---------------- 209 Query: 264 LQSYFRQLWTQPLLPNEQDRLLAALLHPQRLLEYLRLFVLFDRKAGKVVARYQQFFGIRA 323 + L +R LE++ F++FD K K AR+ Q+F I+ Sbjct: 210 -------------------ETIECFLDKKRFLEFIHDFLIFD-KGQKKCARFHQYFAIKK 249 Query: 324 LLERINQRKPDGGREGGVVWHTTGSGKSFTMVFLTKALVLHQSTQVCRVLVVTDRLDLED 383 E I QRK EGG++WHT GSGKS TMV+LT+ + ++ + RVL+VTDR +L+ Sbjct: 250 TQEFI-QRK-----EGGIIWHTQGSGKSLTMVWLTRWI--RRNIKQARVLIVTDRRELDA 301 Query: 384 QLARNFMNSGAFGSAVATKKDGEKA-KVGSGRELAKRIGQGSERIIFTLLQKFATASKLS 442 Q+ G F GEK + S ++L + + + ++ +L+ KF Sbjct: 302 QI------QGVFQGI------GEKIYRADSKKDLLSVLFENKKFLVGSLVHKFDDNDLED 349 Query: 443 ECYNPS-ADMIVLVDEGHRSHGGETHERMRKALPRAAYVAFTGTPLLKKDKTANK--FGS 499 P + IVLVDE HR+ G+ H+ M+ LP A ++AF+GTPLLK+DK ++ FG Sbjct: 350 LKKQPVLKEWIVLVDECHRTQSGKLHKAMKSLLPNAIFIAFSGTPLLKQDKKTSQEVFGD 409 Query: 500 IVHAYTMQRAVEDGTVAPLLYEERVPELTINE-EAVNRWFDRITAGLSPEQAADLKRKFA 558 +H Y AV D V L YE R E ++ E ++ +F+ T L+ +LK+K+ Sbjct: 410 YIHCYKFNEAVSDKVVLDLNYEARSVEQYVSSPEKLDEYFELKTQNLNEAAKTELKKKWV 469 Query: 559 NKQAVYGAANRIELIAWDIAQHFNENIKKLGQGLKGQ--VATASKLEAIRYKQYLDDTGL 616 N Q V+ +R+E I DI + + +L G KG + S A RY + +T L Sbjct: 470 NLQKVFSTKDRLEHIVQDIVLDMAK-LPRLSNG-KGNAMLVAESVYNACRYFELFLETEL 527 Query: 617 VSSAVIISA--PDSRE----GNTEVDESK-----LPEVQKWWNSHVGKNA----EGYEQQ 661 +I++ P+ + G+ E +ES +Q ++N K A + +E++ Sbjct: 528 KDKVAVITSYEPNIADLKDCGSNESEESYKYRAYCKMLQNFFNEKDEKKALNKIKEFEEE 587 Query: 662 VLQDFGSD-GEPDLLIVVDRLLTGFDEPRNTVLYIDKPLKEHSLIQAVARVNRLH-EAKR 719 V + F ++ LLIVVD+LLTGFD P T LYIDK +++H L QAV RVNRL E K Sbjct: 588 VKKRFINEPARMKLLIVVDKLLTGFDAPSLTYLYIDKRMQDHGLFQAVCRVNRLDGEDKD 647 Query: 720 YGVLVDYRGILKELDTAVRAYQDLENRTQGGYELADIEGLYQQMSTEY-KRLPGLHDELW 778 +G ++DY + D+ A+ D N YE DI+GL S + K+L D+L Sbjct: 648 FGCIIDYSDL---FDSLQEAHSDYTNGAFENYEREDIQGLISDKSQKIKKKLEETRDQLK 704 Query: 779 EIFAEVQNKQDLEQYRQLLMPRYAEDEDGQTYDTRQKVRDDFYSALTAFGLCLQTALSSR 838 + V+ +D E Y G + + R FY + AF L + L++ Sbjct: 705 SLCESVKEPKDEEDYIAYFC--------GDNLEKNAQKRRLFYQLVGAF-LRMFVELNN- 754 Query: 839 SFFEDHSFSEADVHRYKEDLRFFTSLRTIARQDALETVDYSVYEQQIRRLVDKQVVGSQV 898 E +S+ + + K++ F+ L+ + + ++VD Y + +RR++D + + Sbjct: 755 --LEKPIYSKEETQQIKQEAGFYRHLQKVVGLSSGDSVDLKSYNEDMRRILDAYI---KT 809 Query: 899 REPKGVYLVHQLGAPEAVEQWS--------EEKTRNETDMI-----RTRLKKTIEQDLAD 945 + + ++ + G E + Q + +NE+ M TR K+ IE++ +D Sbjct: 810 TDSEVLFQIEDQGLCEVLAQMDINDFNKALSQVFKNESSMAESIANNTR-KRIIEKEASD 868 Query: 946 DPYAQK---VFADLLKQAIAEAEAMFDHPLKQYALLKKFEEQVDARDVSGLPAELSESKH 1002 Y +K + DL+ Q E + + L+Q L K + +D D P +++ +K Sbjct: 869 PKYYEKLSSLLNDLILQ-FREKKLTYLEYLQQIQDLAK--KVIDKED-RNYPKKIN-TKA 923 Query: 1003 LRAYFGICR----LVLGEDAFAQTDQA-AWVGQAKEIDAVVRQAVAEHSLNPQNIEAAIR 1057 L+ + L L DA + ++ WVG H+ +N++ A+R Sbjct: 924 LKTLYDNLDENEALALETDACIRGNKKDGWVG---------------HNQKEKNLKIALR 968 Query: 1058 K-----ALLPALFGL 1067 K LL +F L Sbjct: 969 KIINDEVLLENIFNL 983 >HP1402 [V] COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Hpy Helicobacter pylori 26695 Length = 993 Score = 307 bits (786), Expect = 9e-83, Method: Compositional matrix adjust. Identities = 263/913 (28%), Positives = 422/913 (46%), Gaps = 129/913 (14%) Query: 85 LTEGLLPANERVYQMLTLGVTVTEFMPDGKKHQPTIALVDWHDPTANRWDVTEELEVLST 144 L L AN+ Y++L GV + ++ T L+DW D + N + V EE+ S Sbjct: 66 LKNDLYEANQTFYELLIYGVKTK--ISQKNENTQTTWLIDWKDISENEFSVAEEV---SV 120 Query: 145 HGTHHRVPDVVAYVNGLPLVVIEAKRPDASHMGQAMVEEGISQQLRNQRPDEIAQLFAYA 204 G + + PDVV YVNG+ L V+E K+ S VE I Q L NQ+ + I F Sbjct: 121 KGPNAKRPDVVLYVNGIALGVLELKKSSVS------VESAIRQNLDNQKKEFIRDFFKTI 174 Query: 205 QLLLAVSPTEA-RYGTTSTPMKFWARWREEQFSDAQLHEWKNLPLSTDAEAALLAGKPSK 263 QL++A + ++ RYG T K++ W+EE Sbjct: 175 QLVMAGNESQGLRYGVIETEEKYYLSWKEEGV---------------------------- 206 Query: 264 LQSYFRQLWTQPLLPNEQDRLLAALLHPQRLLEYLRLFVLFDRKAGKVVARYQQFFGIRA 323 L++ F + L +R LE++ F++FD K K AR+ Q+F I+ Sbjct: 207 LKNLFETI--------------ECFLKKERFLEFIHDFLIFD-KGKKKCARFHQYFAIKK 251 Query: 324 LLERINQRKPDGGREGGVVWHTTGSGKSFTMVFLTKALVLHQSTQVCRVLVVTDRLDLED 383 E I QRK EGG++WHT GSGKS TMV+LT+ L ++ + RVL+V DR +L+ Sbjct: 252 TQEFI-QRK-----EGGIIWHTQGSGKSLTMVWLTRWL--RRNIKQARVLIVIDRRELDA 303 Query: 384 QLARNFMNSGAFGSAVATKKDGEKAKVGSGRELAKRIGQGSERIIFTLLQKFATASKLSE 443 Q+ F G +KKD L + + E ++ +L+ KF Sbjct: 304 QIKGVFQGIGEDLYRADSKKD-----------LLSALFENKEFLVGSLVHKFDDNDLEDL 352 Query: 444 CYNPS-ADMIVLVDEGHRSHGGETHERMRKALPRAAYVAFTGTPLLKKDKTANK--FGSI 500 P + +VLVDE HR+ + H+ M+ LP A ++AF+GTPLLK+DK ++ FG+ Sbjct: 353 KKQPVLKEWVVLVDECHRTQSAKLHKAMKSLLPNAIFIAFSGTPLLKQDKKTSQEVFGNY 412 Query: 501 VHAYTMQRAVEDGTVAPLLYEER-VPELTINEEAVNRWFDRITAGLSPEQAADLKRKFAN 559 +H Y AV D V L YE R V + + E ++ +F+ T L+ +LK+K+ N Sbjct: 413 IHCYKFNEAVSDRVVLDLNYEARSVDQYVSSPEKLDEYFELKTQCLNDIAKTELKKKWVN 472 Query: 560 KQAVYGAANRIELIAWDIAQHFNENIKKLGQGLKGQVATASKLEAIRYKQYLDDTGLVSS 619 Q V+ +R+ I DI + + + + S A +Y + +T L Sbjct: 473 LQKVFSTKDRLARIVQDIVLDMAKLPRLRSEKGNAMLVAESVYNACQYFELFLETELKDK 532 Query: 620 AVIISA--PDSRE----GNTEVDESK-----LPEVQKWWNSHVGKNA----EGYEQQVLQ 664 +I++ P+ + G+ E +ES +Q +++ K A + +E++V Sbjct: 533 VAVITSYEPNIADLKDCGSDESEESYKYRAYCKMLQNFFDEKDEKKALNKIKEFEEKVKD 592 Query: 665 DFGSDGEPD---LLIVVDRLLTGFDEPRNTVLYIDKPLKEHSLIQAVARVNRLH-EAKRY 720 F + EP+ LLIVVD+LLTGFD P T LYIDK +++H L QAV RVNRL E K + Sbjct: 593 RFIN--EPNRMKLLIVVDKLLTGFDAPSLTYLYIDKKMQDHGLFQAVCRVNRLDGEDKDF 650 Query: 721 GVLVDYRGILKELDTAVRAYQDLENRTQGGYELADIEGLYQQMSTEY-KRLPGLHDELWE 779 G ++DY + D+ + D N+ YE DI+GL + + K+L D+L Sbjct: 651 GCIIDYSDL---FDSLQEVHSDYTNKAFENYEREDIQGLISDKAQKIKKKLEEARDQLRS 707 Query: 780 IFAEVQNKQDLEQYRQLLMPRYAEDEDGQTYDTRQKVRDDFYSALTAFGLCLQTALSSRS 839 + V+ +D Y G + + R FY + AF L + L+ Sbjct: 708 LGESVKEPKDEMDYIAYFC--------GNDLEKNAQKRRLFYQLVGAF-LRMFVELNH-- 756 Query: 840 FFEDHSFSEADVHRYKEDLRFFTSLRTIARQDALETVDYSVYEQQIRRLVDKQVVGSQVR 899 E +S+ ++ + K++ F+ L+ + + ++VD Y +++RR++D + + Sbjct: 757 -LEKPVYSKEEMQQIKQEAEFYRHLQKVVSLSSGDSVDLKSYSEEMRRILDAYIKAT--- 812 Query: 900 EPKGVYLVHQLGAPEAVEQWS--------EEKTRNETDM---IRTRLKKTIEQDLADDPY 948 + K + + G E + Q + +NE+ M I KK I + A DP Sbjct: 813 DSKTLIKIEDQGLCEVLAQMDINDFNKELSQAFKNESSMAESIANNTKKRIIEKEASDPK 872 Query: 949 AQKVFADLLKQAI 961 + + LL I Sbjct: 873 YYEKLSSLLNDLI 885 >XF2739 [V] COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Xfa Xylella fastidiosa 9a5c Length = 1058 Score = 274 bits (700), Expect = 9e-73, Method: Compositional matrix adjust. Identities = 217/736 (29%), Positives = 340/736 (46%), Gaps = 94/736 (12%) Query: 38 RGSTREIILKTRLIEVLQTRRFDYKGESFPLSPGGIDQILRQVQAVNLTEGLLPANERVY 97 R S E++LK R ++ + R + L P +R+V L LL N R++ Sbjct: 53 RASHDEVVLKQRFVDAVA--RLNPG-----LPPEARQDAIRKVTQSELP-SLLEENRRIH 104 Query: 98 QMLTLGVTVTEFMPDGKKHQPTIALVDWHDPTANRWDVTEELEVLSTHGTHHRVPDVVAY 157 +++T GV V + DG +AL+D+ P N W + V++ H ++R PDVV + Sbjct: 105 RLITEGVDVEYYAQDGTLTAGNVALIDFDHPQQNDWLAVNQFVVIADH--YNRRPDVVLF 162 Query: 158 VNGLPLVVIEAKRPDASHMGQAMVEEGISQQLRNQRPDEIAQLFAYAQLLLAVSPTEARY 217 VNGLPL VIE K P + + ++ QL+ + ++I LF LL+ AR+ Sbjct: 163 VNGLPLAVIELKAPGS--INATLI--AAFNQLQTYK-EQIPALFNTNALLVTSDGMTARF 217 Query: 218 GTTSTPMKFWARWREEQFSDAQLHEWKNLPLSTDAEAALLAGKPSKLQSYFRQLWTQPLL 277 G S ++ + WR +TD G P Sbjct: 218 GALSADLERFMPWR-----------------TTDGTDIAPKGVP---------------- 244 Query: 278 PNEQDRLLAALLHPQRLLEYLRLFVLF---DRKAGKVVARYQQFFGIR-ALLERINQRKP 333 E L+ + P RLL+ LR F +F D K++A Y QF +R A+ + P Sbjct: 245 --ELATLIEGICEPHRLLDLLRHFTVFRKTDAGLAKIIAGYHQFHAVRQAINSTVAASSP 302 Query: 334 DGGREGGVVWHTTGSGKSFTMVFLTKALVLHQSTQVCRVLVVTDRLDLEDQLARNFMNSG 393 G + GV+WHT GSGKS M F LV H + ++V+TDR DL+DQL F Sbjct: 303 QGNQRIGVIWHTQGSGKSLLMAFYAGQLVKHPAMANPTLVVLTDRNDLDDQLFTTF---- 358 Query: 394 AFGSAVATKKDGEKAKVGSGRELAKRIGQGSERIIFTLLQKFATASKLSECYNPSADMIV 453 S + + S ++ K + + S +IFT LQKF ++E +++V Sbjct: 359 ---SQCSDLIRQTPVQAQSRDQVRKLLNRASGGVIFTTLQKFG---DITEPLTTRRNVVV 412 Query: 454 LVDEGHRSHGG-----ETH---------ERMRKALPRAAYVAFTGTPLLKKD-KTANKFG 498 + DE HRS G +T + MR ALP A+ + FTGTP+ D T FG Sbjct: 413 IADEAHRSQYGFKAKVDTKTGKISYGFAKYMRDALPNASCIGFTGTPIEADDVNTPAVFG 472 Query: 499 SIVHAYTMQRAVEDGTVAPLLYEERVPELTINEEA---VNRWFDRITAGLSPEQAADLKR 555 + + Y + RAVEDG P+ YE R+ + ++E ++ + +T S + K+ Sbjct: 473 NYIDIYDISRAVEDGATVPIYYESRLARIALDEAEKPQIDAEVNALTEADSEAEQERFKK 532 Query: 556 KFANKQAVYGAANRIELIAWDIAQHFNENIKKLGQGLKGQVATASKLEAIRYKQYLDDTG 615 K+A + + G+ R+ LIA DI H + + L K V S+ + ++ Sbjct: 533 KWATVETLVGSDKRLALIAKDIITHCEDRLAALDG--KAMVVCMSRRICVALYDHI---- 586 Query: 616 LVSSAVIISAPDSREGNTEVDESKLPEVQKWWNSHVGKNAEGYEQQVLQDFGSD-GEP-D 673 V+ + D + G+ ++ + W H+G A + +L + D +P Sbjct: 587 -VALRPDWHSTDHKAGSLKIVMTGTASDPPQWRQHIGNKAR---RDLLAERARDPKDPLK 642 Query: 674 LLIVVDRLLTGFDEPRNTVLYIDKPLKEHSLIQAVARVNRLHEAKRYGVLVDYRGILKEL 733 L+IV D LTGFD P +Y+DKP++ H L+QA+ARVNR+ K G++VDY GI + L Sbjct: 643 LVIVRDMWLTGFDAPCMHTMYLDKPMQGHGLMQAIARVNRVFRDKPAGLIVDYIGIAQNL 702 Query: 734 DTAVRAYQDLENRTQG 749 TA++ Y + + G Sbjct: 703 RTALQQYSKNDQQHTG 718 >MJECL40 [V] COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Mja Methanococcus jannaschii Length = 1042 Score = 274 bits (700), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 221/745 (29%), Positives = 360/745 (48%), Gaps = 91/745 (12%) Query: 6 QTREQYSAHIPALHLLINLGWHFLNTAQ---ALALRGSTREIILKTRLIEVLQTRRFDYK 62 + E Y A+ L NLG+ + + ++ R S R+ ILK R I+ ++ Sbjct: 26 KLNEDYVVENAAIQRLKNLGYSYKHGSELTPEYNERESYRDAILKNRFIKAIKN------ 79 Query: 63 GESFPLSPGGIDQILRQV--QAVNLTEGLLPANERV-YQMLTLGVTVTEFMPDGKKHQPT 119 ++P +++ +V N+ ++ Y+ML GV + EF +G+K Sbjct: 80 -----INPWLTEELALKVYKTVTNIDNPDFNMRGKIFYEMLINGVKL-EFKENGEKKTRF 133 Query: 120 IALVDWHDPTANRWDVTEELEVLSTH-GTHHRVPDVVAYVNGLPLVVIEAKRPDASHMGQ 178 + L+D+ + N + V + EV + R PD+V ++NG+P+ + E K P ++ + Sbjct: 134 VKLIDFENINKNEFLVANQFEVEYYYENGRFRRPDLVVFINGIPIAIFEFKSPKSNQTAK 193 Query: 179 AMVEEGISQQLRNQRPDEIAQLFAYAQLLLAVSPTEARYGTTSTPMKFWARWREEQFSDA 238 + + +I QL+ YAQ+L+ E +YG+ P W R+ Sbjct: 194 DAFND------HKTKMKDIPQLYQYAQILVVSDGLETKYGS---PTSDWDRF-------- 236 Query: 239 QLHEWKNLPLSTDAEAALLAGKPSKLQSYFRQLWTQPLLPNEQDRLLAALLHPQRLLEYL 298 W+ + D E + + + Y +T D LL L + L+E+L Sbjct: 237 --FVWEGVESDDDVEVIEVDNYGNTMYKYKGNPYTS------LDILLMGLFKKEHLIEFL 288 Query: 299 RLFVLFDRKAGKVVARYQQFFGIRALLERINQRKPDG----GREGGVVWHTTGSGKSFTM 354 F++ D+K K++A Y QF+ ++ ++R + G R G+VWH G+GKS TM Sbjct: 289 EDFIIHDKK--KIIATYYQFYTVKKAVDRTIKSVLYGETPEDRRIGIVWHAQGTGKSITM 346 Query: 355 VFLTKALVLHQSTQVCRVLVVTDRLDLEDQLARNFMNSGAFGSAVATKKDGEKAK-VGSG 413 +F K + + ++ +TDRL+L++QL F S F A E+A+ + Sbjct: 347 LFYAKKALKQKELNYPLLVFLTDRLELDEQLYNVF--SSVFSEA-------ERAESIAEL 397 Query: 414 RELAKRIGQGSERIIFTLLQKFATASKLSECYNPSAD---MIVLVDEGHRSHGGETHERM 470 +EL K+ G IIF +QKF SK E Y D +I++ DE HRSH G + + Sbjct: 398 QELIKKTPGG---IIFATIQKFGRKSK-DEHYPFLTDRNNIIIIADEAHRSHYGTLAQNL 453 Query: 471 RKALPRAAYVAFTGTPLLKKDK-TANKFGSIVHAYTMQRAVEDGTVAPLLYEERVPELTI 529 RKA+P A+++AFT TP+ KD+ T FG + AY + +A G V P+ YE R+ EL + Sbjct: 454 RKAIPNASFLAFTATPIDYKDRSTFLVFGDYISAYPIDKAKRHGVVVPIYYEARLVELHL 513 Query: 530 NEEAVNRWFDRITAGLS--PEQAADLKRKFANKQAVYGAANRIELIAWDIAQHFNENIKK 587 E ++ FD I+ ++ PE +K FA + + + + ++ DI +HFN+ ++ Sbjct: 514 TNEFIDLEFDEISERVANDPETKESIKEVFAKLEKIMLTEDYLSKVSKDIIEHFNKRLQD 573 Query: 588 LGQGLKGQVATASKLEAIR-YKQYLDDTGLVSSAVIISAPDSREGNTEVDESKLPEVQKW 646 K V T S+ A+ YK AV++S GN +SK PE Sbjct: 574 FDG--KAMVVTISRKVAVELYKWITKQPNAPKIAVVMS------GN----KSKDPED--- 618 Query: 647 WNSHVGKNAEGYEQQVLQDFGSDGEPDL--LIVVDRLLTGFDEPRNTVLYIDKPLKEHSL 704 ++ H+ E + + ++F D E DL +IVVD LTGFD P +Y KP+K HSL Sbjct: 619 FHPHIRTKKEL--ENLAKEF-KDPESDLKMVIVVDMWLTGFDVPCLHTMYFLKPMKNHSL 675 Query: 705 IQAVARVNRLHEAKRYGVLVDYRGI 729 QA+ARVNR+ + K G++VDY GI Sbjct: 676 AQAIARVNRVFKDKPGGLIVDYIGI 700