BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0024.p (503 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEII0451 [V] COG0286 Type I restriction-modification system met... 347 3e-95 SA1626 [V] COG0286 Type I restriction-modification system methyl... 340 4e-93 SA0391 [V] COG0286 Type I restriction-modification system methyl... 340 5e-93 alr0499 [V] COG0286 Type I restriction-modification system methy... 329 8e-90 L0309 [V] COG0286 Type I restriction-modification system methylt... 325 2e-88 >BMEII0451 [V] COG0286 Type I restriction-modification system methyltransferase subunit Bme Brucella melitensis Length = 518 Score = 347 bits (891), Expect = 3e-95, Method: Compositional matrix adjust. Identities = 204/510 (40%), Positives = 298/510 (58%), Gaps = 38/510 (7%) Query: 15 VWNACDTFRGTVDPSIYKDYVLTMLFLKYISDIWQDHYDRYKAEHGDHPALIEELLKNER 74 +W + D RG++D S YK Y+ LFLK +SD R++ E + ++ + L +N Sbjct: 23 LWKSADILRGSIDSSDYKIYIFGFLFLKRLSD-------RFEEEAKE--SIRQGLPENVA 73 Query: 75 FVLPRSANFYALHDARHQP------GNGERIDKALHAIEEANLTKLRDVFQDISFNS-TK 127 + P F+ + AR G G+ ++KA AIE+AN + V +I FNS ++ Sbjct: 74 YSDPDEHEFFLVERARWSSIKKLTTGIGDHLNKACAAIEDAN-PSIEGVLANIDFNSESR 132 Query: 128 LGDEAQKNDILRHLLEDFAKPELDLRESRVGSLDVIGNAYEFLIKNFASTSGKKAGEFYT 187 LGD + +L L++ F++ +DL + + D++G AYE+LI FA +GKK GEFYT Sbjct: 133 LGDAKNREGVLSRLIDHFSR--IDLSNASLSEPDMLGRAYEYLIDKFADDAGKKGGEFYT 190 Query: 188 PPEVSQLMARLMVPEEGDEICDPTCGSGSLLMKCGQLIRAKAGSR-----KYALFGQEAI 242 P V +L+ L+ P+ G I DPTCGSG +L++ + + G R L GQE Sbjct: 191 PHHVVRLIVELLAPKPGMRISDPTCGSGGMLVQVAEHVAKLEGKRLGEALNITLHGQEKN 250 Query: 243 GSTWALAKMNMFLHAEDNHRIEWGDTLRNPKLLDGKGLLKHFDIVVANPPFSLEKWGHEA 302 TWA+AKMN+ LH + RIE GDT+RNP+LLD G L +D V+ANPPFSL+ WG E Sbjct: 251 LGTWAIAKMNLLLHGLRDARIEKGDTIRNPRLLDQDGNLFLYDRVIANPPFSLDSWGAED 310 Query: 303 AADDPYK----RFRRGLPPRTKADYAFILHMVETMKPGTGRMAVVVPHGVLFRGAAEGNI 358 + D K RF G+PP+ D AF+ HMV T+ G VV+PHGVLFRG+ +G I Sbjct: 311 VSGDTEKKGHNRFIYGIPPKNMGDLAFVQHMVATLNT-KGVCGVVMPHGVLFRGSGDGRI 369 Query: 359 RQKLIEENLLDVVIGLPEKLFYGTGIPAAILMLRKKKSDD---KVLFIDASRDFQDGKNQ 415 R+ +++ +L + +IGLPE LF GTGIPA +L+L K K+ + +VLFI +++F++ + Sbjct: 370 RESMLKADLFEAIIGLPENLFAGTGIPATVLILNKAKATERKGRVLFIHGAKEFEERPKK 429 Query: 416 NILRPQDLERIEQTVRERQSVEKYAYLASPAEIAENEFNLNIPRYVDTFEEAEAIDLKAV 475 NIL ++ RI + +++ + EI EN+FNLNI RY+DT E + ID++A Sbjct: 430 NILGEGNITRIVNAFNAWKDEDRFCRIVDMKEIEENDFNLNISRYIDTLEPEKPIDVQA- 488 Query: 476 REERLKL-KAELAVLE--EKMAGYLKELGY 502 E KL AE A E +M LKE+GY Sbjct: 489 --ELAKLWDAETARDEAAARMNALLKEMGY 516 >SA1626 [V] COG0286 Type I restriction-modification system methyltransferase subunit Sau Staphylococcus aureus N315 Length = 518 Score = 340 bits (872), Expect = 4e-93, Method: Compositional matrix adjust. Identities = 207/525 (39%), Positives = 310/525 (59%), Gaps = 51/525 (9%) Query: 7 QQDAINAAVWNACDTFRGTVDPSIYKDYVLTMLFLKYISDIWQDHYD--------RYKAE 58 QQ ++ +W+ + RG +D S +++Y+L ++F +++S+ + Y Y+ Sbjct: 10 QQAELHKKLWSIANDLRGNMDASEFRNYILGLIFYRFLSEKAEQEYADALSGEDITYQEA 69 Query: 59 HGDHPALIEELLKNE------RFVLPRSANFYALHDARHQPGNGERIDKALHAIEEANLT 112 D E LK E F+ P+ + + Q + E + A+ +E + L Sbjct: 70 WADEE--YREDLKAELIDQVGYFIEPQDLFSAMIREIETQDFDIEHLATAIRKVETSTLG 127 Query: 113 KLRD-----VFQDISFNSTKLGDEAQKNDILRHL----LEDFAKPELDLRESRVGSLDVI 163 + + +F D+ +ST+LG+ ++ L L+D D+ +D++ Sbjct: 128 EESENDFIGLFSDMDLSSTRLGNNVKERTALISKVMVNLDDLPFVHSDME------IDML 181 Query: 164 GNAYEFLIKNFASTSGKKAGEFYTPPEVSQLMARLMV--PEEGDEICDPTCGSGSLLMKC 221 G+AYEFLI FA+T+GKKAGEFYTP +VS+++A+++ ++ + DPTCGSGSLL++ Sbjct: 182 GDAYEFLIGRFAATAGKKAGEFYTPQQVSKILAKIVTDGKDKLRHVYDPTCGSGSLLLRV 241 Query: 222 GQLIRAKAGSRKYALFGQEAIGSTWALAKMNMFLH--AEDNHRIEWGDTLRNPKLLDGKG 279 G+ ++ Y FGQE +T+ LA+MNM LH +N I DTL NP L Sbjct: 242 GK------ETQVYRYFGQERNNTTYNLARMNMLLHDVRYENFEIRNDDTLENPAFLGNT- 294 Query: 280 LLKHFDIVVANPPFSLEKWGHEAAADDPYKRFRRG-LPPRTKADYAFILHMVETMKPGTG 338 FD V+ANPP+S KW ++ ++ + G L P++KAD+AFI HMV + G Sbjct: 295 ----FDAVIANPPYSA-KWTADSKFENDERFSGYGKLAPKSKADFAFIQHMVHYLDD-EG 348 Query: 339 RMAVVVPHGVLFRGAAEGNIRQKLIEE-NLLDVVIGLPEKLFYGTGIPAAILMLRK-KKS 396 MAVV+PHGVLFRGAAEG IR+ LIEE N L+ VIGLP +FYGT IP IL+ +K ++ Sbjct: 349 TMAVVLPHGVLFRGAAEGVIRRYLIEEKNYLEAVIGLPANIFYGTSIPTCILVFKKCRQQ 408 Query: 397 DDKVLFIDASRDFQDGKNQNILRPQDLERIEQTVRERQSVEKYAYLASPAEIAENEFNLN 456 DD VLFIDAS DF+ GKNQN L +ERI T + + +++KY+Y A+ EIA+N++NLN Sbjct: 409 DDNVLFIDASNDFEKGKNQNHLSDAQVERIIDTYKRKATIDKYSYSATLQEIADNDYNLN 468 Query: 457 IPRYVDTFEEAEAIDLKAVREERLKLKAELAVLEEKMAGYLKELG 501 IPRYVDTFEE IDL V+++ + E+A +E+++ YLKELG Sbjct: 469 IPRYVDTFEEEAPIDLDQVQQDLKNIDKEIAEIEQEINAYLKELG 513 >SA0391 [V] COG0286 Type I restriction-modification system methyltransferase subunit Sau Staphylococcus aureus N315 Length = 518 Score = 340 bits (872), Expect = 5e-93, Method: Compositional matrix adjust. Identities = 207/525 (39%), Positives = 311/525 (59%), Gaps = 51/525 (9%) Query: 7 QQDAINAAVWNACDTFRGTVDPSIYKDYVLTMLFLKYISDIWQDHYD--------RYKAE 58 QQ ++ +W+ + RG +D S +++Y+L ++F +++S+ + Y Y+ Sbjct: 10 QQAELHKKLWSIANDLRGNMDASEFRNYILGLIFYRFLSEKAEQEYADALSGEDITYQEA 69 Query: 59 HGDHPALIEELLKNE------RFVLPRSANFYALHDARHQPGNGERIDKALHAIEEANLT 112 D E LK E F+ P+ + + Q + E + A+ +E + L Sbjct: 70 WADEE--YREDLKAELIDQVGYFIEPQDLFSAMIREIETQDFDIEHLATAIRKVETSTLG 127 Query: 113 KLRD-----VFQDISFNSTKLGDEAQKNDILRHL----LEDFAKPELDLRESRVGSLDVI 163 + + +F D+ +ST+LG+ ++ L L+D D+ +D++ Sbjct: 128 EESENDFIGLFSDMDLSSTRLGNNVKERTALISKVMVNLDDLPFVHSDME------IDML 181 Query: 164 GNAYEFLIKNFASTSGKKAGEFYTPPEVSQLMARLMV--PEEGDEICDPTCGSGSLLMKC 221 G+AYEFLI FA+T+GKKAGEFYTP +VS+++A+++ ++ + DPTCGSGSLL++ Sbjct: 182 GDAYEFLIGRFAATAGKKAGEFYTPQQVSKILAKIVTDGKDKLRHVYDPTCGSGSLLLRV 241 Query: 222 GQLIRAKAGSRKYALFGQEAIGSTWALAKMNMFLH--AEDNHRIEWGDTLRNPKLLDGKG 279 G+ ++ Y FGQE +T+ LA+MNM LH +N I DTL NP L Sbjct: 242 GK------ETQVYRYFGQERNNTTYNLARMNMLLHDVRYENFDIRNDDTLENPAFLGNT- 294 Query: 280 LLKHFDIVVANPPFSLEKWGHEAAADDPYKRFRRG-LPPRTKADYAFILHMVETMKPGTG 338 FD V+ANPP+S KW ++ ++ + G L P++KAD+AFI HMV + G Sbjct: 295 ----FDAVIANPPYSA-KWTADSKFENDERFSGYGKLAPKSKADFAFIQHMVHYLDD-EG 348 Query: 339 RMAVVVPHGVLFRGAAEGNIRQKLIEE-NLLDVVIGLPEKLFYGTGIPAAILMLRK-KKS 396 MAVV+PHGVLFRGAAEG IR+ LIEE N L+ VIGLP +FYGT IP IL+ +K ++ Sbjct: 349 TMAVVLPHGVLFRGAAEGVIRRYLIEEKNYLEAVIGLPVNIFYGTSIPTCILVFKKCRQQ 408 Query: 397 DDKVLFIDASRDFQDGKNQNILRPQDLERIEQTVRERQSVEKYAYLASPAEIAENEFNLN 456 DD VLFIDAS DF+ GKNQN L +ERI T + +++++KY+Y A+ EIA+N++NLN Sbjct: 409 DDNVLFIDASNDFEKGKNQNHLSDAQVERIIDTYKRKETIDKYSYSATLQEIADNDYNLN 468 Query: 457 IPRYVDTFEEAEAIDLKAVREERLKLKAELAVLEEKMAGYLKELG 501 IPRYVDTFEE IDL V+++ + E+A +E+++ YLKELG Sbjct: 469 IPRYVDTFEEEAPIDLDQVQQDLKNIDKEIAEIEQEINAYLKELG 513 >alr0499 [V] COG0286 Type I restriction-modification system methyltransferase subunit Nos Nostoc sp. PCC 7120 Length = 537 Score = 329 bits (844), Expect = 8e-90, Method: Compositional matrix adjust. Identities = 209/543 (38%), Positives = 309/543 (56%), Gaps = 62/543 (11%) Query: 7 QQDAINAAVWNACDTFRGTVDPSIYKDYVLTMLFLKYISDIWQDHYDRYKAEHGDHPALI 66 Q+ + +WN D+ RG ++ ++DY L +F KY+S+ + + AE G I Sbjct: 8 QKKKLETQLWNIADSLRGKMNADEFRDYCLGFIFYKYLSERQHLYANEVLAEDGIDFINI 67 Query: 67 EELLKN------------------------------ERFVLPRSANFYALHDARHQPGNG 96 +E K ER + ++A+ L D + N Sbjct: 68 DESSKEGQEYLEAIKEESIATLGYFLKPSELFSSLAERALGAKTASEENLADEDFEASNF 127 Query: 97 --ERIDKALHAIEEANLTK-----LRDVFQDISFNSTKLGDEAQ-KNDILRHLLEDFAKP 148 + + + L +IE + + K +F+D+ STKLG + KN ++ +L K Sbjct: 128 ILDDLTQVLSSIERSTMGKESEEDFDHLFEDLDLTSTKLGRTPKAKNALIAKILVHLNKI 187 Query: 149 ELDLRESRVGSLDVIGNAYEFLIKNFASTSGKKAGEFYTPPEVSQLMARLMVPEEG--DE 206 + L ++ DV+G+AYE+LI FAS +GKKAGEFYTP +VS+++A+++ + Sbjct: 188 DFRLEDTES---DVLGDAYEYLIGQFASGAGKKAGEFYTPQQVSKVLAKIVTTGKSRLKS 244 Query: 207 ICDPTCGSGSLLMKCGQLIRAKAGSRKYALFGQEAIGSTWALAKMNMFLHAED--NHRIE 264 + DPTCGSGSLL++ + + + +GQE +T+ LA+MNM LH N + Sbjct: 245 VYDPTCGSGSLLLRVAREVESVGD-----FYGQEMNRTTYNLARMNMILHGVHYRNFDLR 299 Query: 265 WGDTLRNPKLLDGKGLLKHFDIVVANPPFSLEKWGHEA--AADDPYKRFRRGLPPRTKAD 322 DTL NP+ +G+ F+ VVANPPFS + W +DD + ++ + L P +KAD Sbjct: 300 QEDTLENPQ---HEGM--RFEAVVANPPFSAQ-WSANKLFESDDRFSQYGK-LAPASKAD 352 Query: 323 YAFILHMVETMKPGTGRMAVVVPHGVLFRGAAEGNIRQKLIEE-NLLDVVIGLPEKLFYG 381 +AF+ HM+ + G MAVV+PHGVLFRGAAEG+IR+ +I+E N LD VIGLP +FYG Sbjct: 353 FAFVQHMIHHLDD-NGIMAVVLPHGVLFRGAAEGHIRKYVIKERNWLDAVIGLPANIFYG 411 Query: 382 TGIPAAILMLRK-KKSDDKVLFIDASRDFQDGKNQNILRPQDLERIEQTVRERQSVEKYA 440 T IP IL+ +K +++ D +LFIDAS F+ KNQN LR +D+E+I T R+R EKY+ Sbjct: 412 TSIPTCILVFKKCRENPDDILFIDASAYFEKAKNQNYLRDEDVEKIVSTYRQRIQSEKYS 471 Query: 441 YLASPAEIAENEFNLNIPRYVDTFEEAEAIDLKAVREERLKLKAELAVLEEKMAGYLKEL 500 Y A EIAEN+FNLNIPRYVDTFEE E IDL AV E ++ E+ ++ + G+ +EL Sbjct: 472 YRAPLTEIAENDFNLNIPRYVDTFEEEEEIDLDAVAREIREIDREMVETDQLIRGFCEEL 531 Query: 501 GYE 503 G E Sbjct: 532 GIE 534 >L0309 [V] COG0286 Type I restriction-modification system methyltransferase subunit Lla Lactococcus lactis Length = 515 Score = 325 bits (832), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 189/519 (36%), Positives = 303/519 (58%), Gaps = 49/519 (9%) Query: 15 VWNACDTFRGTVDPSIYKDYVLTMLFLKYIS-------------DIWQDHYDRYKAEHGD 61 +W + RG + + YKDY+ +LF KY+S D W++ YD+ Sbjct: 11 MWALLNQTRGQIGLTAYKDYIFGLLFYKYLSEKATQWLGEVLRGDTWENVYDQ------- 63 Query: 62 HPALIEELLKNERFVLPRSANFY-----ALHDARHQ-PGNGERIDKALHAIEEANLTKLR 115 P + +K + + F+ A+H+ R P + I Sbjct: 64 DPVRALDYMKQKLGYAIQPKEFFKDWEAAIHEERFNIPMISDTFGHFNQQIAFEAKDDFE 123 Query: 116 DVFQDISFNSTKLGDEAQ-KNDILRHLLEDFAKPELDLRESRVGSLDVIGNAYEFLIKNF 174 +F + F+S+ LG AQ + ++ ++E + PE DL D + + YE+L++ F Sbjct: 124 GIFDGMRFDSSDLGSNAQARASVMISMIELLSAPEFDLSTGG----DTVSDIYEYLLEKF 179 Query: 175 ASTSGKKAGEFYTPPEVSQLMARLMVPEEGDE----ICDPTCGSGSLLMKCGQLIR--AK 228 A+ G++YTP E+S++MAR++ + DE I DP GS SLL+ ++ + Sbjct: 180 ATVLASDMGQYYTPKEISEVMARILTFGKADEDNFSIYDPAVGSASLLITTASHMKHSNQ 239 Query: 229 AGSRKYALFGQEAIGSTWALAKMNMFLH--AEDNHRIEWGDTLRNP---KLLDGKGLLKH 283 G+ KY FGQE + + LA+MN+ +H ++ +I DTL + +++GK + Sbjct: 240 RGAIKY--FGQEKDATPYRLARMNLMMHNIEYNDIQIHHADTLESDWPDGVIEGKDTPRM 297 Query: 284 FDIVVANPPFSLEKWGHEAAADDPYKRFRR-GLPPRTKADYAFILHMVETMKPGTGRMAV 342 FD V+ANPP+S W ++ DDP RFR G+ P+TKADY+F+LH + K +GR+A+ Sbjct: 298 FDAVMANPPYSAH-WNNKDREDDP--RFREYGIAPKTKADYSFLLHCLYHTKE-SGRVAI 353 Query: 343 VVPHGVLFRGAAEGNIRQKLIEENLLDVVIGLPEKLFYGTGIPAAILMLRKKKSDDKVLF 402 ++PHGVLFRGAAEG IR+ LI+++ ++ VIG P+KLF TGIP +L+L+K +++ +LF Sbjct: 354 ILPHGVLFRGAAEGRIRKALIDKHQIEAVIGFPDKLFLNTGIPVCVLILKKNRANSDILF 413 Query: 403 IDASRDFQDGKNQNILRPQDLERIEQTVRERQSVEKYAYLASPAEIAENEFNLNIPRYVD 462 +DAS+ F+ KNQ LRP+D+++I +TV R++V+KY++LA+ E+ EN++NLNIPRYVD Sbjct: 414 VDASQGFEKMKNQKQLRPEDIDKITETVIHRKAVDKYSHLATLEEVIENDYNLNIPRYVD 473 Query: 463 TFEEAEAIDLKAVREERLKLKAELAVLEEKMAGYLKELG 501 TFEE E+IDL ++ + ++ AE+A + +A Y KELG Sbjct: 474 TFEEEESIDLADIQGQIDEVDAEIAKANQTLANYFKELG 512