BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0013.p (908 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value MA2106 [V] COG4096 Type I site-specific restriction-modification... 614 e-175 SP0892 [V] COG4096 Type I site-specific restriction-modification... 412 e-114 MA2418 [V] COG4096 Type I site-specific restriction-modification... 412 e-114 RSc3394 Non COG 304 7e-82 STM4526 [V] COG4096 Type I site-specific restriction-modificatio... 198 6e-50 >MA2106 [V] COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Mac Methanosarcina acetivorans str.C2A Length = 955 Score = 614 bits (1583), Expect = e-175, Method: Compositional matrix adjust. Identities = 359/949 (37%), Positives = 542/949 (57%), Gaps = 54/949 (5%) Query: 1 MTSRNEAQTRTEIIDSQLARAGWSKNRRTLL------------EEYLLTAAEPAANGGIS 48 M NE QTR ID L GW N R+ + ++ E N S Sbjct: 3 MLDLNEFQTRKLKIDILLKEQGWDVNDRSKVVLEVDTKQSDFKKQDYKQVNETRRNDAES 62 Query: 49 QFADYVLLGADGSPIAVVEAKSSSRDEIAGKRQASDYADAIKAKFGVDPFVFLTNGKEIQ 108 ++ADY+LL + G P+A++EAK +++D I G++QA +YAD IKA+ G + F+FL+NG +I Sbjct: 63 KYADYLLLDSTGKPLAIIEAKRTTKDPILGQKQAEEYADDIKAQTGKEVFIFLSNGYQIW 122 Query: 109 FWDRERYAPRKVSGFYTRDDLERLRHQRQFAEPLHKVSINADIAGRVYQNEAIRRITEGV 168 WDRERY PR++ GFY+ DLERL +QR+ +E ++ I+ I R E R+ E + Sbjct: 123 LWDRERYGPRQLKGFYSLKDLERLLYQRKNSELEAEIDIDGSIVDRAKSIEVATRVVEHI 182 Query: 169 DAAKRKFLLVMATGTGKTRTTIALVDALLRSKRTQRVLFLADRRELVRQAMSE-FKSHLP 227 RK L+VMATGTGKTR +A++D L+R R QRVLFL DR+ L +QA + + P Sbjct: 183 HKGHRKALIVMATGTGKTRVAMAIIDQLIREGRVQRVLFLTDRKALRKQAYEKGYLRFFP 242 Query: 228 NESVARIEMGE-TSGARIQFATYPSMMQVYS--------RLSVGYYDLIVADESHRSIYQ 278 E+ I G S R+ +T + ++Y+ R+S G +DLI +DE+HRSIY Sbjct: 243 EETKEIILSGNYNSNCRLYVSTIQTFQEIYNQKDRNEMYRISPGAFDLIFSDEAHRSIYS 302 Query: 279 RYKAIFDHFDAIQLGLTATPTDYIDHNTFELFDCGDRVPSYYYSYEQAIADKNLVNYR-- 336 ++K IF + DAIQ+GLTATP D +D +TF F+C D +P+ YSYE A+ D L ++R Sbjct: 303 KWKGIFTYLDAIQIGLTATPADMVDRDTFRFFECNDDIPTALYSYEDAVRDAVLCDFRKN 362 Query: 337 VLDAQTTFQLQGIQGDALPEPLKQMARDQGVELDELNFDGSDIEKSIVNQGTNDAIVREF 396 + A+T FQ++GI+ + L E ++ +G++ DE+NF+G+++EK I +GT++AIVREF Sbjct: 363 ISGARTYFQIEGIKPENLTEGEREELIKKGIDPDEINFEGTELEKKIAVKGTSEAIVREF 422 Query: 397 MERSRKDERG-LPHKSIVFAISHAHAKRIYEGFNRLYPELQREGMVEIIDSHMERAEATL 455 ME D+ G LP K+I FAIS HAKR++E F +LYPE + + + II S RA+ + Sbjct: 423 MENCLTDQAGTLPAKTIFFAISKLHAKRLWEAFEKLYPEYKGK-LARIIVSEDSRAQQLI 481 Query: 456 NDFKYRAMPRVAISVDMLDTGVDIPAIQNLVFAKPVFSKVKFWQMIGRGTRL-----HTD 510 DF+ + PR+AISVDM+DTG+D+P + NLVFAKPVFSK+KFWQM+GRGTR H + Sbjct: 482 KDFEEKPFPRIAISVDMMDTGIDVPEVCNLVFAKPVFSKIKFWQMLGRGTRADGACEHRE 541 Query: 511 KATGEPKKDFLIIDHWRNFAFFKLKPDGEIDHPSEPLPVRLFRLRLEKW-QLLHAQQQDT 569 K+ F + D W NF ++ + P+G + +E + R+F RL++ +L+ + + Sbjct: 542 WLPDGKKEYFKVFDFWNNFEYWNMNPEGVQNESAEAITNRIFLTRLKQLGELMQHRDPAS 601 Query: 570 QDAVLDLQAM----LQTLPRHSINVRPHWDELD-ALMIK-WPDPSKSVVEHISKTIAPLT 623 + A ++A +++LPR S+NVR H +++ AL K W + + VE + K I PL Sbjct: 602 EKAAEQVKAKIISDIESLPRDSVNVREHLQDVEKALSPKLWDNIAVDPVEFLQKKIMPLM 661 Query: 624 VLGPLAGLDELQFRIWCERLTVAWLKADGGEQSKMKERIQEAISSLTPNLPEVRRVAEQL 683 P L E F + CE+L A L+ D E ++K I E + L L VR + Sbjct: 662 KFKPDVNLKEATFTLRCEKLAYALLENDKAEIDRLKTSIAEMVDRLPRTLDSVRAKEALM 721 Query: 684 SWVTSVGFWMHLDMARLAALQSLFAPLMRYRAEIPGDTVEINLPDSIAQRS-WIIYGPTG 742 V S FW + + L S APLM Y A+ P +T+ I++ D IA+R W I G Sbjct: 722 DNVLSRSFWETVSFEDVQLLLSDLAPLMPYMAKEPRETIVIDMSDIIAERKEWQISG-GN 780 Query: 743 EGAFAESYRERVEVLVRQLANQLPELTKLKQGQKLNDTELERISETLNHTDLFVTEDTLR 802 + ++ E+YR VE +R LA P + K+K + L D +LE++ ETL + DL T D + Sbjct: 781 DPSYVEAYRREVEACIRALAETHPAVRKIKNNEPLTDYDLEQLEETLLNADL--TPDNPK 838 Query: 803 --------MAFEAPSASLADFLRHILCDDAHLPNREERINAAFDAFIAAHG-YLRANQLN 853 + + ASL DF+R +L + P + I AF +I + + ++QLN Sbjct: 839 LSSLASLSNLYPSRHASLVDFIRQVLGLYSS-PAPDALIKDAFQTYIIENNKHYSSDQLN 897 Query: 854 FLRAVKAAVLRHGRITRAALSEPPLSRVGQVE--TLFPLSEITELINLA 900 F+ ++ L+ I + L +PP + G +F E+ I++ Sbjct: 898 FILTLQTVFLKKKHIEYSTLWQPPFTNFGTTSPFPMFTQEELNSFIDIC 946 >SP0892 [V] COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Spn Streptococcus pneumoniae TIGR4 Length = 1091 Score = 412 bits (1060), Expect = e-114, Method: Compositional matrix adjust. Identities = 311/953 (32%), Positives = 487/953 (51%), Gaps = 87/953 (9%) Query: 5 NEAQTRTEIIDSQLARAGWSKNRRTLLEEYLLTAAEPAANGGISQFADYVLLGADGSPIA 64 +EA+TR ID L AGW +E A + +G + DYVL G +G +A Sbjct: 177 SEAETRKLFIDIDLRLAGWIFEENCRVE----IAVDGLKHGSGIGYCDYVLYGKNGKILA 232 Query: 65 VVEAKSSSRDEIAGKRQASDYADAIKAKFGVDPFVFLTNGKEIQFWDRERYAP--RKVSG 122 +VEAK +S + G+ Q +YA+A++ G P F+TNG + D P R+++G Sbjct: 233 IVEAKKASVNPEVGEVQVKEYAEALEKHIGYQPICFITNGLKHYILD----GPNRRQIAG 288 Query: 123 FYTRDDLERLRHQRQFAEPLHKVS--INADIAGRVYQNEAIRRITEGVDAAKRKFLLVMA 180 FY++++L+ + +R +PL +S I DI+GR YQ AI + E +R+ LLVMA Sbjct: 289 FYSQEELQLVMDRRHLQKPLEDISSKIRDDISGRHYQKHAIASVCEAFSDHRRQALLVMA 348 Query: 181 TGTGKTRTTIALVDALLRSKRTQRVLFLADRRELVRQAMSEFKSHLPNESVARIEMGETS 240 TG GKTRT ++LVD L R + VLFLADR LV+QA F+ LP+ SV + + Sbjct: 349 TGAGKTRTAVSLVDILSRHNWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNF-LEDKE 407 Query: 241 GA---RIQFATYPSMMQVYSR--------LSVGYYDLIVADESHRSIYQRYKAIFDHFDA 289 GA R+ F+TYP+M+ S +VG++DLI+ DESHRSIYQ+YK+IFD+FDA Sbjct: 408 GAQSSRMVFSTYPTMIGAISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDA 467 Query: 290 IQLGLTATPTDYIDHNTFELFDCGDRVPSYYYSYEQAIADKNLVNYRVLDAQTTFQLQGI 349 +GLTATP +D NT+ F+ + VP+Y Y E+A+ D LV Y ++ + G+ Sbjct: 468 RIVGLTATPRQDLDKNTYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGL 527 Query: 350 QGDALPEPLKQ----MARDQGVELDELNFDGSDIEKSIVNQGTNDAIVREFMER----SR 401 D L E K+ D E D DGS I N+ T + ++ E M R + Sbjct: 528 HYDDLSEEEKEHFDSKFEDNSCEKD---IDGSVFNSFIFNKSTVEIVLNELMTRGIQTAS 584 Query: 402 KDERGLPHKSIVFAISHAHAKRIYEGFNRLYPELQREGMVEIIDSHMERAEATLNDFKYR 461 DE G K+I+FA +H HA+ I FN YPE + ++ID ++ + ++DFK + Sbjct: 585 GDEIG---KTIIFAKNHDHAEYIRGIFNNRYPE-KGSDYAQVIDYSIKHYQTLIDDFKIK 640 Query: 462 -AMPRVAISVDMLDTGVDIPAIQNLVFAKPVFSKVKFWQMIGRGTRLHTDKATGEP-KKD 519 P++AISVDMLDTG+D+P + NLVF K V SK KFWQMIGRGTRL D E K++ Sbjct: 641 EKYPQIAISVDMLDTGIDVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKEN 700 Query: 520 FLIIDHWRNFAFFKLKP-DGEIDHPSEPLPVRLFRLRLEKWQLLHA-QQQDTQDA----- 572 FL+ D+ NF +F+ P DGE H L RLF ++++ + L Q Q+ Q A Sbjct: 701 FLVFDYGDNFDYFRADPRDGEGRHIV-SLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQ 759 Query: 573 --VLDLQAMLQTLPRHSINVRPHWDELDAL--MIKWPDPSKSVVEHISKTIAPLTVLGPL 628 V +LQ +++L VR D + + + W + + E I K ++PL L Sbjct: 760 QLVSELQGRIESLNELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPL--LFDE 817 Query: 629 AGLDEL--QFRIWCERLTVAWLKADGGE-QSKMKERIQEAISSLTPNLPEVRRVAEQLSW 685 DE+ +F +W + + L A + A+S++ N+P+V AE + Sbjct: 818 DKEDEMARRFDLWLLHIQLGQLTAKSSTVHISQVMKTARALSAI-GNIPQVFEQAEIIRK 876 Query: 686 VTSVGFWMHLDMARLAALQSLFAPLMRYRAEIPGDTVEINLPDSIAQRSWIIYGPTGEGA 745 V FW ++++ L ++ L+++ + +N D I ++ T A Sbjct: 877 VQEPEFWKEVNLSDLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILS---TVHETT---A 930 Query: 746 FAE-----SYRERVEVLVRQLANQLPELTKLKQGQKLNDTELERISETLNHTDLFVTEDT 800 F + SY E+VE ++ ++ ++KL +KL ++ + + L + ++ Sbjct: 931 FLQVNDLRSYNEKVEHYLKTHLDE-ESISKLYHNKKLTSDDMLALEKLL--WEKLGSKAD 987 Query: 801 LRMAFEAPSASLADFLRHILCDDAHLPNREERINAAFDAFIAAHGYLRANQLNFLRAVKA 860 + +E + ++ +R I+ D NR F F++ L A Q++F++ + Sbjct: 988 YQSHYE--NKAIPRLVREIIGLDRESANR------IFSKFLSDEN-LNARQISFVKLIVD 1038 Query: 861 AVLRHGRITRAALSEPPLSRVGQVETLFP-----LSEITELINLANQLVDEAA 908 ++ +G + L++ P G V+ LF L I ++I L N EAA Sbjct: 1039 YIVENGFLETKVLTQEPFKSYGSVQLLFQHQLPVLRNIVQIIELINNRAGEAA 1091 >MA2418 [V] COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Mac Methanosarcina acetivorans str.C2A Length = 1146 Score = 412 bits (1059), Expect = e-114, Method: Compositional matrix adjust. Identities = 308/955 (32%), Positives = 488/955 (51%), Gaps = 76/955 (7%) Query: 5 NEAQTRTEIIDSQLARAGWSKNRRTLLEEYLLTAAEPAANGGISQFADYVLLGADGSPIA 64 +EA+TR +ID L AGW ++ E +L P NG + DYVL G DG P+A Sbjct: 205 SEAETRKSLIDLLLKEAGWPLDKTQDKEFEVL--GMPNKNG--VGYVDYVLWGDDGKPLA 260 Query: 65 VVEAKSSSRDEIAGKRQASDYADAIKAKFGVDPFVFLTNGKEIQFWDRERYAPRKVSGFY 124 +VEAK +++D G++QA YA+ ++ +FG P +F +NG E WD Y PR+V GFY Sbjct: 261 LVEAKRTTKDPQVGQQQAKLYANCLENQFGQRPVIFYSNGYETWIWDDSLYPPRQVQGFY 320 Query: 125 TRDDLERLRHQRQFAEPLHKVSINADIAGRVYQNEAIRRITEGVDAAK-RKFLLVMATGT 183 + +LE L +R PL + IN+ I R YQ AIRRI E + RK L+VMATG Sbjct: 321 KKAELELLIQRRSSRRPLSEAEINSAIVERYYQTRAIRRIGEAFEQDNDRKALIVMATGA 380 Query: 184 GKTRTTIALVDALLRSKRTQRVLFLADRRELVRQAMSEFKSHLPNESVARIEMGETSGAR 243 GKTRT IAL D L+R +RVLFLADR LV QA++ FK HLP+ + + + + R Sbjct: 381 GKTRTVIALCDLLMRCNWVKRVLFLADRVALVNQAVNAFKRHLPDSAPVNLVTEKDTEGR 440 Query: 244 IQFATYPSMMQVYS-------RLSVGYYDLIVADESHRSIYQRYKAIFDHFDAIQLGLTA 296 + +TYP+MM+ R VG++DL++ DE+HRS++++Y+AIFD+FD++ +GLTA Sbjct: 441 VFVSTYPTMMKQIEEINGGQRRFGVGHFDLVIIDEAHRSVFKKYRAIFDYFDSLLVGLTA 500 Query: 297 TPTDYIDHNTFELFDCGDRVPSYYYSYEQAIADKNLVNYRVLDAQTTFQLQGIQGDALPE 356 TP + I+ NT+ LFD VP+ Y E+A+ D LV + + FQ QGI D L + Sbjct: 501 TPKNEIERNTYSLFDLEPGVPTDAYQLEEAVKDGFLVPPKAVSVPLKFQRQGINYDELSD 560 Query: 357 PLKQM--ARDQGVELDEL--NFDGSDIEKSIVNQGTNDAIVREFMERSRK----DERGLP 408 K+ A D G E E+ + + K + N+ T D ++ MER K D G Sbjct: 561 EDKEQWEALDWGDEDGEIPERVEAEAVNKWLFNKDTVDKVLAHLMERGLKVAGGDRLG-- 618 Query: 409 HKSIVFAISHAHAKRIYEGFNRLYPELQREGMVEIIDSHMERAEATLNDFKYRAM-PRVA 467 K+I+FA + AHA+ + E FN YP + E +I E A++ +++F + P +A Sbjct: 619 -KTILFAKNQAHAEYVAERFNVNYPHFKGE-FARVITFKTEYAQSLIDNFSIKEKDPHIA 676 Query: 468 ISVDMLDTGVDIPAIQNLVFAKPVFSKVKFWQMIGRGTRLHTDK-ATGEPKKDFLIIDHW 526 +SVDMLDTG+D+P + NLVF K V SK KFWQM+GRGTRL D GE K+ F + D+ Sbjct: 677 LSVDMLDTGIDVPEVVNLVFFKLVRSKTKFWQMVGRGTRLCPDLFEPGEDKRFFYLFDYC 736 Query: 527 RNFAFFKLKPDGEIDHPSEPLPVRLFRLRLEKWQLLHAQQQDTQDAVLDLQA-------M 579 +N FF P+ + L RLF+ RLE L + + D + + + Sbjct: 737 QNLEFFSQNPETTEGALGDSLGTRLFKSRLELLSELDKKLEADSDCEVGTETREIYGEPI 796 Query: 580 LQTLPRHSINVRPHWD----ELDALMIKWPDPSKSVVEHISKTIAPLTVLG--------P 627 + RHSI H + LD +++ P + +VE S++ A L + G Sbjct: 797 TEAEVRHSIAETLHSEIASMNLDNFVVR---PKRRLVERYSRSEAWLKLSGEDLSELSHE 853 Query: 628 LAGL---------DELQFRIWCERLTVAWLKADGGEQSKMKERIQEAISSLTPNLPEVRR 678 +AGL + +F + L +A L+A+ + +++ ++++ I+ L + Sbjct: 854 VAGLPSEMEPEAEEAKRFDLLVLNLQLALLRAEPAFE-RLRNQVRD-IAGLLEEKSAIPM 911 Query: 679 VAEQLSWVTSVG---FWMHLDMARLAALQSLFAPLMRYRAEIPGDTVEINLPDSIAQRSW 735 V +Q++ + V +W ++ L L+ +++ + + + D + + Sbjct: 912 VRDQMALILDVQTDEWWENVTTPMLETLRRRLRDIVKLIEKHRRKPIYTDFEDEMGSENN 971 Query: 736 I-IYGPTGEGAFAESYRERVEVLVRQLANQLPELTKLKQGQKLNDTELERISETLNHTDL 794 + + G G F E +R + + + +Q + KL+ + L +L+ + L+ + L Sbjct: 972 VELPGFAAAGDF-EKFRAKTRAFLLEHQDQAV-IHKLRMNKPLTAADLDELERILSESGL 1029 Query: 795 FVTEDTLRMAFEAPSASLADFLRHILCDDAHLPNREERINAAFDAFIAAHGYLRANQLNF 854 E+ + S L F+R ++ D E +F F+A L ANQ+ F Sbjct: 1030 GGPEEIAHA--KEVSNGLGLFVRSLIGLD------REAAKQSFARFLAGKT-LVANQIEF 1080 Query: 855 LRAVKAAVLRHGRITRAALSEPPLSRVGQ--VETLFPLSEITELINLANQLVDEA 907 + + + HG + A L E P + + + LF +++ ELI Q+ A Sbjct: 1081 INRIIDHLTEHGAMDAALLYESPFTDLTPQGPDGLFTSAQVDELIAALEQITATA 1135 >RSc3394 Non COG Length = 954 Score = 304 bits (778), Expect = 7e-82, Method: Compositional matrix adjust. Identities = 206/574 (35%), Positives = 311/574 (54%), Gaps = 31/574 (5%) Query: 5 NEAQTRT--EIIDSQLARAGWSKNRRTLLEEYLLTAAEPAANGGISQFADYVLLGADGSP 62 +E+QT + ID L AGW + A P G + DYVL P Sbjct: 22 SESQTAACGDAIDRLLHAAGWPLTGPD--DTAFPLAGLPTPPG--KAYVDYVLWDDRRKP 77 Query: 63 IAVVEAKSSSRDEIAGKRQASDYADAIKAKFGVDPFVFLTNGKEIQFWDRERYAPRKVSG 122 +A+VEA+ + R+ AG+++A YAD ++A G P ++ TNG++ FWD PR V G Sbjct: 78 LAIVEARHTRRNTRAGQQRARQYADGLEALTGQRPLIYYTNGRDHWFWDDRAGPPRAVQG 137 Query: 123 FYTRDDLERLRHQRQFAEPLHKVSINADIAGRVYQNEAIRRITEGVDAAK-RKFLLVMAT 181 F+ +D+LERL R +PL +I+ IAGR YQ+ AIRRI E + + R L+ MA Sbjct: 138 FHRQDELERLLGCRTHRQPLATAAIDTAIAGRPYQHRAIRRIAEAFEQDRLRAALVSMAP 197 Query: 182 GTGKTRTTIALVDALLRSKRTQRVLFLADRRELVRQAMSEFKSHLPNESVARIEMGETSG 241 GTGKTRT IAL + L+R + +R LFLADR + +A + F +HLP ++ + + Sbjct: 198 GTGKTRTAIALTELLMRCRWIKRTLFLADRTAQLTRAAAAFAAHLPQATLVNLAKDAGAD 257 Query: 242 ARIQFATYPSM-------MQVYSRLSVGYYDLIVADESHRSIYQRYKAIFDHFDAIQLGL 294 + +T P+M + R G++DL++ + +HR I +R++AIF HFDA+++GL Sbjct: 258 GDVYLSTCPTMQDRIAHPIDTVPRFGPGHFDLVIVNIAHRGICRRHRAIFSHFDALRVGL 317 Query: 295 TATPTDYIDHNTFELFDCGDRVPSYYYSYEQAIADKNLVNYRVLDAQTTFQLQGIQGDAL 354 TA P D ID +T+ LFD +P+ Y ++AIAD +LV R + G+ DAL Sbjct: 318 TAMPEDEIDRDTYRLFDLETGIPTDAYDLDEAIADHHLVPPRAVCVPVRQPRGGMAYDAL 377 Query: 355 PEPLKQMARDQGVELDELNFDG-------SDIEKSIVNQGTNDAIVREFME-RSRKDERG 406 + K D G L E N +G + + +Q T DA++ ME R R+ G Sbjct: 378 SDAEK----DHGDAL-EWNDNGHANTAVPDTADACLHHQDTVDAMIALVMEKRGRRVADG 432 Query: 407 -LPHKSIVFAISHAHAKRIYEGFNRLYPELQREGMVEIIDSHMERAEATLNDFKYR-AMP 464 K+++FA +H HA+ I F+ YP+ + + +I +A+ ++ F MP Sbjct: 433 DWIGKTLIFASNHDHARFIAGRFDANYPQYKGR-LACVITYEAGQAQTLIDAFSVADRMP 491 Query: 465 RVAISVDMLDTGVDIPAIQNLVFAKPVFSKVKFWQMIGRGTRLHTD-KATGEPKKDFLII 523 RVAI+ +LDTG+ +P + NLVF + V SK +F QM+G GTR + G+ K+D L+ Sbjct: 492 RVAIAAGLLDTGIAVPEVVNLVFFRLVRSKARFRQMVGCGTRPCKNLYGPGQDKQDVLLF 551 Query: 524 DHWRNFAFFKLKPDGEIDHPSEPLPVRLFRLRLE 557 D +N AFF ++ + + PL RLFR RLE Sbjct: 552 DFCQNLAFFDMRLEAAAETMPVPLEQRLFRARLE 585 >STM4526 [V] COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Sty Salmonella typhimurium LT2 Length = 1169 Score = 198 bits (503), Expect = 6e-50, Method: Compositional matrix adjust. Identities = 185/620 (29%), Positives = 288/620 (46%), Gaps = 147/620 (23%) Query: 5 NEAQTRTEIIDSQLARAGWSKNRRTLLEEYLLTA-AEPAANGGISQ------------FA 51 NE ++R +ID+QL +AGW + +TL + A EP N I++ FA Sbjct: 240 NEEESRF-LIDAQLRKAGWQADSKTL--RFAKGARPEPGVNKAIAEWPTGTDETGKTGFA 296 Query: 52 DYVLLGADGSPIAVVEAKSSSRDEIAGKRQASDYA----------------------DAI 89 DYVL PIAVVEAK + D + ++ Y+ DA+ Sbjct: 297 DYVLF-IGLKPIAVVEAKRKNTDVSSKLNESYRYSKYFDNGFLRDTLLEHYAPDEVHDAV 355 Query: 90 ------------KAKFGVDPFVFLTNGKEIQFWDRERYAPRKVSGFYTRDDLERLRHQRQ 137 K +F + PF + TNG+E R A + SG + RD +RH Sbjct: 356 PEYEISWQDTSGKQRFKI-PFCYSTNGREY------RAAMKTKSGIWYRD----VRHTTN 404 Query: 138 FAEPL---HKVSINADIAG---------------------RVYQNEAIRRITEGVDAAKR 173 ++ L H+ D+ G R YQ +A+R + + + ++ Sbjct: 405 MSKALPEWHRPEELLDMLGSDPQKQNQWFAENPGMSELGLRYYQEDAVRAVEQAIVNGQQ 464 Query: 174 KFLLVMATGTGKTRTTIALVDALLRSKRTQRVLFLADRRELVRQAMSEFKSHLPN----E 229 LL MATGTGKTRT IAL+ L++S+R +RVLFL DRR L QA+ F+ N Sbjct: 465 HILLAMATGTGKTRTAIALMFRLIQSQRFKRVLFLVDRRSLGEQALGAFEDTRINGDTFN 524 Query: 230 SVARIEMGET-----SGARIQFATYPSM----MQVYSRLSVGYYDLIVADESHRS----- 275 S+ I+ G T +I AT S+ +Q + VG YD IV DE+HR Sbjct: 525 SIFDIK-GLTDKFPEDSTKIHVATVQSLVKRTLQSDEPMPVGRYDCIVVDEAHRGYILDK 583 Query: 276 --------------IYQRYKAIFDHFDAIQLGLTATPTDYIDHNTFELFDCGDRVPSYYY 321 Y+ I DHFDA+++ LTATP +T ++F G+ P Y Y Sbjct: 584 EQTEGELQFRSQLDYVSAYRRILDHFDAVKIALTATPA----LHTVDIF--GE--PVYRY 635 Query: 322 SYEQAIADKNLVNYR------VLDAQTTFQL-QGIQGDALPEPLKQMARDQGVELDELNF 374 +Y A+ D L++ +AQ L +G Q + L P ++ D D+ +F Sbjct: 636 TYRTAVIDGYLIDQDPPIQIVTRNAQDGVYLSEGEQVERL-NPQGELINDTLA--DDQDF 692 Query: 375 DGSDIEKSIVNQGTNDAIVREFMERSRKDERGLPHKSIVFAISHAHAKRIYE----GFNR 430 + +D + +V N A+ E + D G K++VF +++AHA + + F + Sbjct: 693 EVADFNRGLVIPAFNRAVCGELTKYL--DPTG-QQKTLVFCVTNAHADMVVDELRSAFKK 749 Query: 431 LYPELQREGMVEII---DSHMERAEATLNDFKYRAMPRVAISVDMLDTGVDIPAIQNLVF 487 YP+L+ + +++I D ++ ++ + F +P + ++VD+L TGVDIP+I N+VF Sbjct: 750 KYPQLEHDAIIKITGDADKDAKKVQSMIVRFNKERLPNIVVTVDLLTTGVDIPSICNIVF 809 Query: 488 AKPVFSKVKFWQMIGRGTRL 507 + V S++ + QM GR TRL Sbjct: 810 LRKVKSRILYEQMKGRATRL 829