BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4624.p (475 letters) Database: BlastDatabases/707/707 3697 sequences; 1,221,021 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|152982183|ref|YP_001354785.1| major facilitator transporter [... 543 e-155 gi|152982589|ref|YP_001352814.1| major facilitator superfamily m... 105 5e-24 gi|152980367|ref|YP_001352036.1| major facilitator superfamily d... 94 1e-20 gi|152982526|ref|YP_001355122.1| major facilitator superfamily d... 80 3e-16 gi|152982562|ref|YP_001352191.1| major facilitator superfamily d... 78 1e-15 >gi|152982183|ref|YP_001354785.1| major facilitator transporter [Janthinobacterium sp. Marseille] Length = 469 Score = 543 bits (1398), Expect = e-155, Method: Compositional matrix adjust. Identities = 299/468 (63%), Positives = 357/468 (76%) Query: 1 MSSQPSSSGAPAPQPHIVIAGEGLPPERRGRAILALGIAVGLATLDTAIANTALPAMALD 60 M S S + A H V+ +GLP R AI+++ I VG+A+LDTAIANTALPAMA+ Sbjct: 1 MGSSDMSRQSGAVVNHEVLEQDGLPENERRWAIVSVAIGVGMASLDTAIANTALPAMAMQ 60 Query: 61 LKTTPAASVWIVTAYQLAMMVALLPLAALGEIVGYRRIYIWGLVLFTAASLLCAVAWSLP 120 L TPA SVWIV YQLAM+ LLP AALGEI+GYRRI I+GL+LFTAASL CA AWSLP Sbjct: 61 LNATPADSVWIVNIYQLAMVATLLPFAALGEILGYRRIAIFGLLLFTAASLACAYAWSLP 120 Query: 121 TLVIARFLQGLGGAGIMSVNTALIRFIYPTRSLGRGVGLNTLIVAIAFTVGPSVASGILA 180 TLVIARF QG+G + IM VNTAL+R IYP R LGRG+G N L+VA+AF VGP+ AS IL+ Sbjct: 121 TLVIARFFQGVGASAIMGVNTALLRSIYPARMLGRGLGTNALVVAVAFAVGPTTASLILS 180 Query: 181 IAPWPWLFAVNVPLGVAAVILALPSLPHTKLSSHAFDLRSAVLNAAAFGLLILAIGEGAH 240 + WPWLFA+NVPLG+ A LA LPHTK ++H FD +A+ NA FGLLILAIGEGAH Sbjct: 181 VWSWPWLFAINVPLGLFAYFLARKVLPHTKRATHKFDALTAIYNAGGFGLLILAIGEGAH 240 Query: 241 QAELKVVGLELAAAIVCGLLLLKRELSHPAPMLPVDLFRHPMFTLSAITAVCSFAAQGLA 300 ++ K V LEL A+V +LLL+R+ H APMLPVDLFR P+FTLSA+TAVC+FAAQ LA Sbjct: 241 LSDAKTVALELFGALVFFILLLRRQKGHAAPMLPVDLFRRPLFTLSALTAVCTFAAQSLA 300 Query: 301 FVSLPFFFHHDLGRSQVEIGLLMTPWPVAVAIMAPIAGRLSDHYPVGILGGVGLAILCVG 360 FVSLPF+F LGRS +E G L+TPW V V IMAPIAGRLSDHYP G+LGGVGL++L G Sbjct: 301 FVSLPFYFETVLGRSAIETGFLITPWAVMVGIMAPIAGRLSDHYPPGMLGGVGLSVLSAG 360 Query: 361 LLWMTFMPAAPSVWEISWRMLLCGMGFGFFQSPNLKALMTSAPPHRSGGASGIVATARLL 420 ++ + M SV+ I WRM LCG+GFGFFQ+PNL+A+M+SAPP R G ASG+VAT+RLL Sbjct: 361 MVSLILMSPDVSVFGICWRMALCGIGFGFFQAPNLRAIMSSAPPERGGSASGVVATSRLL 420 Query: 421 GQSVGAALVALCFNLSETHGSRLALGFGAAFAGVACIASFLRLLTRNP 468 GQ+ GAALVA CF +S HG LALG GAAFA A IASF+RL + P Sbjct: 421 GQASGAALVAFCFIISTQHGETLALGLGAAFAATASIASFMRLFVQQP 468 >gi|152982589|ref|YP_001352814.1| major facilitator superfamily multidrug resistance B translocase [Janthinobacterium sp. Marseille] Length = 517 Score = 105 bits (263), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 97/424 (22%), Positives = 191/424 (45%), Gaps = 11/424 (2%) Query: 34 LALGIAVGLATLDTAIANTALPAMALDLKTTPAASVWIVTAYQLAMMVALLPLAALGEIV 93 LAL +AV + LD++IAN ++PA++ DL +P W++T++ +A +++ L + + Sbjct: 22 LALSLAVFMNVLDSSIANVSIPAISGDLGVSPQQGTWVITSFSVANAISVPLTGWLTQRI 81 Query: 94 GYRRIYIWGLVLFTAASLLCAVAWSLPTLVIARFLQGLGGAGIMSVNTALIRFIYPTRSL 153 G R++I ++LF AS LC A S+ L+ AR LQG ++ ++ AL+ YP Sbjct: 82 GQVRLFIGSILLFVLASCLCGFAPSIEILIAARVLQGAVAGPMIPLSQALLLSSYPPAKS 141 Query: 154 GRGVGLNTLIVAIAFTVGPSVASGILAIAPWPWLFAVNVPLGVAAVILALPSLPHTKLSS 213 G + + +A +GP + I WPW+F +N+P+G+ A + + Sbjct: 142 GMALAFWGMTTLVAPIMGPLLGGWISDNYTWPWIFFINIPIGLFAAWATWSIYKERESRT 201 Query: 214 HAF--DLRSAVLNAAAFGLLILAIGEGA-----HQAELKVVGLELAAAIVCGLLLLKREL 266 + D VL G L L + +G H E+ ++ + A+V + + E+ Sbjct: 202 YKLPIDKVGLVLLVLWVGSLQLMLDKGKELDWFHSGEIIILA---SVAVVAFIYFVIWEI 258 Query: 267 SHPAPMLPVDLFRHPMFTLSAITAVCSFAAQGLAFVSLPFFFHHDLGRSQVEIGLLMTPW 326 P++ + LF+ F+ I ++ + V LP + +G + E G +M P Sbjct: 259 GEEHPVVDLSLFKGRNFSGGVIAISVAYGLFFGSLVILPLWLQTQIGYTATEAGKVMAPV 318 Query: 327 PVAVAIMAPIAGRLSDHYPVGILGGVGLAILCVGLLWMTFMPAAPSVWEISWRMLLCGMG 386 + I++PI G++ + I + + + + ++ G Sbjct: 319 GIFAIILSPIVGKMLPKIDARWVATTAFLIFSLVFFMRSQFTQDVDMMTLMIPTVIQGAA 378 Query: 387 FGFFQSPNLKALMTSAPPHRSGGASGIVATARLLGQSVGAALVALCF-NLSETHGSRLAL 445 F P +++ P + A+G+ R++ +G ++++ + N + H ++LA Sbjct: 379 MAMFFIPLTSIILSGQAPDKIPAAAGLSNFVRIMFGGIGTSVMSTMWDNRTILHHAQLAE 438 Query: 446 GFGA 449 GA Sbjct: 439 YTGA 442 >gi|152980367|ref|YP_001352036.1| major facilitator superfamily drug efflux transporter [Janthinobacterium sp. Marseille] Length = 478 Score = 94.4 bits (233), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 79/257 (30%), Positives = 130/257 (50%), Gaps = 6/257 (2%) Query: 36 LGIAVGLATLDTAIANTALPAMALDLKTTPAASVWIVTAYQLAMMVALLPLAALGEIVGY 95 + IA+ + LD+ I NTA+P+MA L TP + +V++Y LA+ V++ + + G Sbjct: 24 VAIALFMEQLDSTIINTAIPSMAASLHVTPLSLKAVVSSYILALAVSIPISGWMADRFGT 83 Query: 96 RRIYIWGLVLFTAASLLCAVAWSLPTLVIARFLQGLGGAGIMSVNTALIRFIYPTRSLGR 155 RR++ + LFT +S+LC ++ ++P LV AR LQG A +M V + +P L Sbjct: 84 RRVFSVAVGLFTFSSILCGLSVNVPMLVAARILQGFSAAMMMPVGRLTVIRTFPKSELLA 143 Query: 156 GVGLNTLIVAIAFTVGPSVASGILAIAPWPWLFAVNVPLGVAAVILALPSLPHTKLSS-H 214 + + I +GP+V I+ PW +F VNVP+G+AA + +P + S Sbjct: 144 AMNFVIIPALIGPLLGPTVGGLIVHWLPWQAIFFVNVPIGLAAQWMIHRHMPDYRSDSPR 203 Query: 215 AFDLRSAVLNAAAFGLL--ILAI-GEGAHQAELKVVGLELAAAIVCGLLLLKRELSHPAP 271 D+ VL + LL IL I GE A + ++ A++ +L R H P Sbjct: 204 PLDVIGLVLFGSGVALLSWILEIFGEHYLDATSTTILFIISLALLGAYILHARRTLH--P 261 Query: 272 MLPVDLFRHPMFTLSAI 288 +L + LF+ F +S + Sbjct: 262 LLQLTLFKTRTFRVSVV 278 >gi|152982526|ref|YP_001355122.1| major facilitator superfamily drug efflux transporter [Janthinobacterium sp. Marseille] Length = 481 Score = 80.1 bits (196), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 100/411 (24%), Positives = 179/411 (43%), Gaps = 11/411 (2%) Query: 43 ATLDTAIANTALPAMALDLKTTPAASVWIVTAYQLAMMVALLPLAALGEIVGYRRIYIWG 102 A L + I N A+P ++ + W+ T + LAM +++L L G RR Y Sbjct: 32 AILSSTIVNVAIPDLSRYFVLGQERAQWVSTGFMLAMTLSMLLTPWLLLRFGLRRTYGGA 91 Query: 103 LVLFTAASLLCAVAWSLPTLVIARFLQGLGGAGIMSVNTALIRFIYPTRSLGRGVGLNTL 162 + L ++ + + P L+ R L+GL + + +I + G+ +G+ Sbjct: 92 ICLLLIGGVVGGFSINYPMLLSMRVLEGLASGVMQPIPAIVILRAFDQHEQGKAMGIFGF 151 Query: 163 IVAIAFTVGPSVASGILAIAPWPWLF---AVNVPLGVAAVILALPSLPHTKLSSHAFDLR 219 V +A VGPSV ++ + W +F + + + L S S D + Sbjct: 152 GVVLAPAVGPSVGGFLVELFGWRSIFFVVVPPCLVVLVLIQRFLASYTPVPDSDKPLDWK 211 Query: 220 SAVLNAAAFGLLILAIGEGAHQAELKVVGLELAAAIVCGLLLLKRELSHPAPMLPVDLFR 279 +L + L+ + E VV L + A + G +L + S P++ + LFR Sbjct: 212 GLLLIGVSIVSLLNGVVELRGDMPQAVVLLVIGVATLIGFILYQTRTS-AEPLMNMQLFR 270 Query: 280 HPMFTLSAITA-VCSFAAQGLAFVSLPFFFHHDLGRSQVEIGLLMTPWPVAVAIMAPIAG 338 H F + A+ A + G ++ LP + + + + GL++ P + +A+ P+AG Sbjct: 271 HRQFAMGALVAFIYGMGLFGSTYL-LPIYMQMGMNYAPSQAGLVLLPAGIVLAVTIPLAG 329 Query: 339 RLSDHYPVGILGGVGLAILCVGLLWM-TFMPAAPSVWEISWRML-LCGMGFGFFQSPNLK 396 RL+D YP +L +GL +L M PA + ++W ++ G+GF + +L Sbjct: 330 RLADRYPPNVLVAIGLFLLAASFALMANGSPATSYLALMAWAVIGRIGLGF-VLPALSLG 388 Query: 397 ALMTSAPPHRSGGASGIVATARLLGQSVGAALVALCFNLS-ETHGSRLALG 446 A+ + GAS I R LG ++G +LV + H ++ ALG Sbjct: 389 AMRGLDIGLVAQGASAI-NFVRQLGGAIGVSLVGVVLEWRIALHQAQSALG 438 >gi|152982562|ref|YP_001352191.1| major facilitator superfamily drug efflux transporter [Janthinobacterium sp. Marseille] Length = 518 Score = 77.8 bits (190), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 113/445 (25%), Positives = 203/445 (45%), Gaps = 26/445 (5%) Query: 14 QPHIVIAGEGLPPERRGRAILALGIAVGLATLDTAIANTALPAMALDLKTTPAASVWIVT 73 I+ LP R + + +A+ L +D + ALP + DL + +A +WIV Sbjct: 5 DKQILKHTSTLPSSSRWLVLAIVSVALLLIVVDMTVLYAALPRLTADLTASASAKLWIVN 64 Query: 74 AYQLAMMVALLPLAALGEIVGYRRIYIWGLVLFTAASLLCAVAWSLPTLVIARFLQGLGG 133 Y L + LL + LG+ +G++ ++I GLV+F ASL A + S TL+ +R L +G Sbjct: 65 IYALTVSGLLLGMGTLGDRLGHKSLFIAGLVVFGIASLCAAYSPSSATLIASRALLAVGA 124 Query: 134 AGIMSVNTALIRFIYPTRSLGRGVGLNTLIVAIAF---TVGPSVASGILAIAPWPWLFAV 190 A +M ++IR + + R V + + ++AF +GP V +L W +F + Sbjct: 125 AMMMPATLSIIRLAFADEN-ERAVAIG-IWASVAFGGAALGPVVGGLLLEYFWWGSVFLI 182 Query: 191 NVPLGVAAVILALPSLPHTKLS-SHAFDLRSAVLNAAAFGLLILAIGE-GAHQAELKVVG 248 NVP+ + A+ +AL +P K + + +DL ++ A + A+ E G + + Sbjct: 183 NVPIVLVALPIALAYIPKGKANKTRPWDLIGSLQIMAGLVGVTYALKEAGKREPAWGIAL 242 Query: 249 LELAAAIVCGLLLLKRELSHPAPMLPVDLFRHPMFTLSAITAVCSFAAQGLAFVSLPFFF 308 L L I + +R+ PM+ LF++ +F+ S AV + A A + + F Sbjct: 243 LVLLVGIFFLAVFARRQQHSAHPMIDFSLFKNTIFSSSVAAAVVAAA----ALLGMELVF 298 Query: 309 HHD----LGRSQVEIGLLMTPWPVAVAIMAPIAGRLSDHYPVGILGGVGLAILCVGLLWM 364 L + ++ G+ + P +A + P+ GR+ + + L I +G+ Sbjct: 299 TQRLQLVLDMTPLQAGVFILPLSLAAFVAGPLTGRVLPRLGSAYVLSLSLLISGLGMGAY 358 Query: 365 TFMPAAPSVWEISWRMLLC----GMGFGFFQSPNLKALMTSAPPHRSGGASGIVATARLL 420 F+ A +W ++C G G G + +M SAP R+G A+ + + L Sbjct: 359 LFLYDAA-----AWIQIICLLVLGAGIGAAMTAASGTIMQSAPVDRAGMAASVEEVSYEL 413 Query: 421 GQSVGAALVALCFNLSETHGSRLAL 445 G G L+ +L+ + S L+L Sbjct: 414 GSVFGVTLMGSILSLA--YASTLSL 436 Database: BlastDatabases/707/707 Posted date: Apr 13, 2011 12:58 PM Number of letters in database: 1,221,021 Number of sequences in database: 3697 Lambda K H 0.326 0.139 0.430 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 3697 Number of Hits to DB: 932,989 Number of extensions: 34649 Number of successful extensions: 241 Number of sequences better than 1.0e-08: 10 Number of HSP's gapped: 226 Number of HSP's successfully gapped: 10 Length of query: 475 Length of database: 1,221,021 Length adjustment: 87 Effective length of query: 388 Effective length of database: 899,382 Effective search space: 348960216 Effective search space used: 348960216 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 131 (55.1 bits)