BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1365.p (446 letters) Database: BlastDatabases/707/707 3697 sequences; 1,221,021 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|152980367|ref|YP_001352036.1| major facilitator superfamily d... 290 1e-79 gi|152982589|ref|YP_001352814.1| major facilitator superfamily m... 131 7e-32 gi|152982526|ref|YP_001355122.1| major facilitator superfamily d... 125 5e-30 gi|152982562|ref|YP_001352191.1| major facilitator superfamily d... 101 9e-23 gi|152982183|ref|YP_001354785.1| major facilitator transporter [... 67 2e-12 >gi|152980367|ref|YP_001352036.1| major facilitator superfamily drug efflux transporter [Janthinobacterium sp. Marseille] Length = 478 Score = 290 bits (743), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 175/446 (39%), Positives = 264/446 (59%), Gaps = 2/446 (0%) Query: 1 MDSTVISTSLPPLALDMKVDPISLKLALTSYLVSLAVFIPISGWMADRFGSLTIFRAAIC 60 +DST+I+T++P +A + V P+SLK ++SY+++LAV IPISGWMADRFG+ +F A+ Sbjct: 33 LDSTIINTAIPSMAASLHVTPLSLKAVVSSYILALAVSIPISGWMADRFGTRRVFSVAVG 92 Query: 61 VFMLGSILCGMSSTLPQFVAARFLQGIGGAMMVPVGRLVILRSVEKVNLVKALSYLTIPA 120 +F SILCG+S +P VAAR LQG AMM+PVGRL ++R+ K L+ A++++ IPA Sbjct: 93 LFTFSSILCGLSVNVPMLVAARILQGFSAAMMMPVGRLTVIRTFPKSELLAAMNFVIIPA 152 Query: 121 LFGPVLGPPLGGFITTYFHWRWIFFINIPISVLGLYLATRFIPDLKAEQVSPLDFKGFVL 180 L GP+LGP +GG I + W+ IFF+N+PI + ++ R +PD +++ PLD G VL Sbjct: 153 LIGPLLGPTVGGLIVHWLPWQAIFFVNVPIGLAAQWMIHRHMPDYRSDSPRPLDVIGLVL 212 Query: 181 SALGCSLLMMGLATAGRHLVSGDVALACVVAGTLFLAGYVWHARRATAPLIDLALLKIPT 240 G +LL L G H + + L Y+ HARR PL+ L L K T Sbjct: 213 FGSGVALLSWILEIFGEHYLDATSTTILFIISLALLGAYILHARRTLHPLLQLTLFKTRT 272 Query: 241 LRAGVFGGSLYRVGIGAIPFLLPLMLQLGFGYTPFHSGLLTCASAAGAMFMKTIAARFLR 300 R V GG + R+G+G +PFLLPL+ QLG G + SGL+ +AA AM MK I+ R L Sbjct: 273 FRVSVVGGFITRLGVGGLPFLLPLLYQLGLGLPAWQSGLMMMPTAAAAMAMKLISVRVLG 332 Query: 301 RFGFRRVLLVNGALGVLGLCAIATFTPTTPYLLMVLILLIGGCFRSLQFTSLNAISYADV 360 FG+R+VL+VN + + + + TP+TP +++L+ L G F SLQF+S+N+++Y+D+ Sbjct: 333 HFGYRKVLIVNTVMIGVTISLFSIITPSTPIAVILLLGLAQGFFNSLQFSSMNSMAYSDI 392 Query: 361 DNLRLSQATSMASVAQQLSIGMGVVLAGF--ALQMSNEIQGHSELVAQDFWPAFLVVAAV 418 + S A+++AS QQ+S+ G+ A + + Q V AFL + + Sbjct: 393 NPEDSSMASTIASSMQQMSMSFGLAFGSIIAAWYLGDLPQSDRAAVGNALHHAFLTLGGL 452 Query: 419 ASLALLMLRQLPPNAGAEMAGQEENK 444 ++ L L PN G ++ Sbjct: 453 TIISSLSFWALRPNDGESVSKAHTTS 478 >gi|152982589|ref|YP_001352814.1| major facilitator superfamily multidrug resistance B translocase [Janthinobacterium sp. Marseille] Length = 517 Score = 131 bits (330), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 94/312 (30%), Positives = 159/312 (50%), Gaps = 8/312 (2%) Query: 1 MDSTVISTSLPPLALDMKVDPISLKLALTSYLVSLAVFIPISGWMADRFGSLTIFRAAIC 60 +DS++ + S+P ++ D+ V P +TS+ V+ A+ +P++GW+ R G + +F +I Sbjct: 33 LDSSIANVSIPAISGDLGVSPQQGTWVITSFSVANAISVPLTGWLTQRIGQVRLFIGSIL 92 Query: 61 VFMLGSILCGMSSTLPQFVAARFLQGIGGAMMVPVGRLVILRSVEKVNLVKALSYLTIPA 120 +F+L S LCG + ++ +AAR LQG M+P+ + ++L S AL++ + Sbjct: 93 LFVLASCLCGFAPSIEILIAARVLQGAVAGPMIPLSQALLLSSYPPAKSGMALAFWGMTT 152 Query: 121 LFGPVLGPPLGGFITTYFHWRWIFFINIPISVLGLYLATRFIPDLKAEQVS-PLDFKGFV 179 L P++GP LGG+I+ + W WIFFINIPI + + + ++ P+D G V Sbjct: 153 LVAPIMGPLLGGWISDNYTWPWIFFINIPIGLFAAWATWSIYKERESRTYKLPIDKVGLV 212 Query: 180 LSALGCSLLMMGLATAGRHLV---SGDVALACVVAGTLFLAGYVWHARRATAPLIDLALL 236 L L L + L G+ L SG++ + VA F+ +W P++DL+L Sbjct: 213 LLVLWVGSLQLML-DKGKELDWFHSGEIIILASVAVVAFIYFVIWEIGE-EHPVVDLSLF 270 Query: 237 KIPTLRAGVFGGSL-YRVGIGAIPFLLPLMLQLGFGYTPFHSGLLTCASAAGAMFMKTIA 295 K GV S+ Y + G++ +LPL LQ GYT +G + A+ + I Sbjct: 271 KGRNFSGGVIAISVAYGLFFGSL-VILPLWLQTQIGYTATEAGKVMAPVGIFAIILSPIV 329 Query: 296 ARFLRRFGFRRV 307 + L + R V Sbjct: 330 GKMLPKIDARWV 341 >gi|152982526|ref|YP_001355122.1| major facilitator superfamily drug efflux transporter [Janthinobacterium sp. Marseille] Length = 481 Score = 125 bits (314), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 115/455 (25%), Positives = 213/455 (46%), Gaps = 22/455 (4%) Query: 1 MDSTVISTSLPPLALDMKVDPISLKLALTSYLVSLAVFIPISGWMADRFGSLTIFRAAIC 60 + ST+++ ++P L+ + + T +++++ + + ++ W+ RFG + AIC Sbjct: 34 LSSTIVNVAIPDLSRYFVLGQERAQWVSTGFMLAMTLSMLLTPWLLLRFGLRRTYGGAIC 93 Query: 61 VFMLGSILCGMSSTLPQFVAARFLQGIGGAMMVPVGRLVILRSVEKVNLVKALSYLTIPA 120 + ++G ++ G S P ++ R L+G+ +M P+ +VILR+ ++ KA+ Sbjct: 94 LLLIGGVVGGFSINYPMLLSMRVLEGLASGVMQPIPAIVILRAFDQHEQGKAMGIFGFGV 153 Query: 121 LFGPVLGPPLGGFITTYFHWRWIFFINIPISVLGLYLATRFIPDLK--AEQVSPLDFKGF 178 + P +GP +GGF+ F WR IFF+ +P ++ L L RF+ + PLD+KG Sbjct: 154 VLAPAVGPSVGGFLVELFGWRSIFFVVVPPCLVVLVLIQRFLASYTPVPDSDKPLDWKGL 213 Query: 179 VLSALGCSLLMMGLATAGRHLVSGDVALACV--VAGTLFLAGYVWHARRATA-PLIDLAL 235 +L + L+ G+ + GD+ A V V G L G++ + R +A PL+++ L Sbjct: 214 LLIGVSIVSLLNGVVE-----LRGDMPQAVVLLVIGVATLIGFILYQTRTSAEPLMNMQL 268 Query: 236 LKIPTLRAGVFGGSLYRVGIGAIPFLLPLMLQLGFGYTPFHSGLLTCASAAGAMFMKTI- 294 + G +Y +G+ +LLP+ +Q+G Y P +GL+ AG + TI Sbjct: 269 FRHRQFAMGALVAFIYGMGLFGSTYLLPIYMQMGMNYAPSQAGLVLL--PAGIVLAVTIP 326 Query: 295 -AARFLRRFGFRRVLLVNGALGVLGLCAIATFTPTTPYLLMVLILLIGGCFRSLQFTSLN 353 A R R+ ++ + L +A +P T YL ++ +IG +L+ Sbjct: 327 LAGRLADRYPPNVLVAIGLFLLAASFALMANGSPATSYLALMAWAVIGRIGLGFVLPALS 386 Query: 354 AISYADVDNLRLSQATSMASVAQQLSIGMGVVLAGFALQMSNEIQGHSELVAQD-----F 408 + +D ++Q S + +QL +GV L G L+ + + D F Sbjct: 387 LGAMRGLDIGLVAQGASAINFVRQLGGAIGVSLVGVVLEWRIALHQAQSALGTDSHRNAF 446 Query: 409 WPAFLVVA---AVASLALLMLRQLPPNAGAEMAGQ 440 F +VA A+A +A +R+ P E A + Sbjct: 447 NETFFLVAVLCAIAVVAAWYMREKPMTKDQEAAEK 481 >gi|152982562|ref|YP_001352191.1| major facilitator superfamily drug efflux transporter [Janthinobacterium sp. Marseille] Length = 518 Score = 101 bits (251), Expect = 9e-23, Method: Compositional matrix adjust. Identities = 102/396 (25%), Positives = 177/396 (44%), Gaps = 4/396 (1%) Query: 1 MDSTVISTSLPPLALDMKVDPISLKLALTSYLVSLAVFIPISGWMADRFGSLTIFRAAIC 60 +D TV+ +LP L D+ + + Y ++++ + G + DR G ++F A + Sbjct: 36 VDMTVLYAALPRLTADLTASASAKLWIVNIYALTVSGLLLGMGTLGDRLGHKSLFIAGLV 95 Query: 61 VFMLGSILCGMSSTLPQFVAARFLQGIGGAMMVPVGRLVI-LRSVEKVNLVKALSYLTIP 119 VF + S+ S + +A+R L +G AMM+P +I L ++ A+ Sbjct: 96 VFGIASLCAAYSPSSATLIASRALLAVGAAMMMPATLSIIRLAFADENERAVAIGIWASV 155 Query: 120 ALFGPVLGPPLGGFITTYFHWRWIFFINIPISVLGLYLATRFIPDLKAEQVSPLDFKGFV 179 A G LGP +GG + YF W +F IN+PI ++ L +A +IP KA + P D G + Sbjct: 156 AFGGAALGPVVGGLLLEYFWWGSVFLINVPIVLVALPIALAYIPKGKANKTRPWDLIGSL 215 Query: 180 LSALGCSLLMMGLATAGRHLVSGDVALACVVAGTLFLAGYVWHARRATAPLIDLALLKIP 239 G + L AG+ + +AL ++ G FLA + + + P+ID +L K Sbjct: 216 QIMAGLVGVTYALKEAGKREPAWGIALLVLLVGIFFLAVFARRQQHSAHPMIDFSLFKNT 275 Query: 240 TLRAGVFGGSLYRVGIGAIPFLLPLMLQLGFGYTPFHSGLLTCASAAGAMFMKTIAARFL 299 + V + + + + LQL TP +G+ + A + R L Sbjct: 276 IFSSSVAAAVVAAAALLGMELVFTQRLQLVLDMTPLQAGVFILPLSLAAFVAGPLTGRVL 335 Query: 300 RRFGFRRVLLVNGALGVLGLCAIATFTPTTPYLLMVLILLIG-GCFRSLQFTSLNAISYA 358 R G VL ++ + LG+ A ++ ++ +L++G G ++ S + A Sbjct: 336 PRLGSAYVLSLSLLISGLGMGAYLFLYDAAAWIQIICLLVLGAGIGAAMTAASGTIMQSA 395 Query: 359 DVDNLRLSQATSMASVAQQLSIGMGVVLAGFALQMS 394 VD R A S+ V+ +L GV L G L ++ Sbjct: 396 PVD--RAGMAASVEEVSYELGSVFGVTLMGSILSLA 429 >gi|152982183|ref|YP_001354785.1| major facilitator transporter [Janthinobacterium sp. Marseille] Length = 469 Score = 67.4 bits (163), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 55/241 (22%), Positives = 107/241 (44%), Gaps = 6/241 (2%) Query: 1 MDSTVISTSLPPLALDMKVDPISLKLALTSY-LVSLAVFIPISGWMADRFGSLTIFRAAI 59 +D+ + +T+LP +A+ + P + Y L +A +P + + + G I + Sbjct: 45 LDTAIANTALPAMAMQLNATPADSVWIVNIYQLAMVATLLPFAA-LGEILGYRRIAIFGL 103 Query: 60 CVFMLGSILCGMSSTLPQFVAARFLQGIGGAMMVPVGRLVILRSVEKVNLV-KALSYLTI 118 +F S+ C + +LP V ARF QG+G + ++ V +LRS+ ++ + L + Sbjct: 104 LLFTAASLACAYAWSLPTLVIARFFQGVGASAIMGV-NTALLRSIYPARMLGRGLGTNAL 162 Query: 119 PALFGPVLGPPLGGFITTYFHWRWIFFINIPISVLGLYLATRFIPDLKAEQVSPLDFKGF 178 +GP I + + W W+F IN+P+ + +LA + +P K D Sbjct: 163 VVAVAFAVGPTTASLILSVWSWPWLFAINVPLGLFAYFLARKVLPHTK-RATHKFDALTA 221 Query: 179 VLSALGCSLLMMGLATAGRHLVSGDVALACVVAGTLFLAGYVWHARRATAPLIDLALLKI 238 + +A G LL++ + G HL + +F + + AP++ + L + Sbjct: 222 IYNAGGFGLLILAIGE-GAHLSDAKTVALELFGALVFFILLLRRQKGHAAPMLPVDLFRR 280 Query: 239 P 239 P Sbjct: 281 P 281 Database: BlastDatabases/707/707 Posted date: Apr 13, 2011 12:58 PM Number of letters in database: 1,221,021 Number of sequences in database: 3697 Lambda K H 0.329 0.142 0.428 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 3697 Number of Hits to DB: 863,291 Number of extensions: 31739 Number of successful extensions: 206 Number of sequences better than 1.0e-08: 10 Number of HSP's gapped: 196 Number of HSP's successfully gapped: 10 Length of query: 446 Length of database: 1,221,021 Length adjustment: 86 Effective length of query: 360 Effective length of database: 903,079 Effective search space: 325108440 Effective search space used: 325108440 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.8 bits) S2: 131 (55.1 bits)