BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0517.p (484 letters) Database: BlastDatabases/707/707 3697 sequences; 1,221,021 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|152982183|ref|YP_001354785.1| major facilitator transporter [... 288 6e-79 gi|152982562|ref|YP_001352191.1| major facilitator superfamily d... 114 2e-26 gi|152982589|ref|YP_001352814.1| major facilitator superfamily m... 109 4e-25 gi|152982526|ref|YP_001355122.1| major facilitator superfamily d... 108 6e-25 gi|152980367|ref|YP_001352036.1| major facilitator superfamily d... 102 6e-23 >gi|152982183|ref|YP_001354785.1| major facilitator transporter [Janthinobacterium sp. Marseille] Length = 469 Score = 288 bits (736), Expect = 6e-79, Method: Compositional matrix adjust. Identities = 171/431 (39%), Positives = 251/431 (58%), Gaps = 16/431 (3%) Query: 10 DEGLPGQQRRRAMLAVMTATTMAVFDGTIINVALPQISLALHTSAAASVWVANAYLLATA 69 +GLP +RR A+++V MA D I N ALP +++ L+ + A SVW+ N Y LA Sbjct: 21 QDGLPENERRWAIVSVAIGVGMASLDTAIANTALPAMAMQLNATPADSVWIVNIYQLAMV 80 Query: 70 MTLAVFAALSSRLGFRTQFTAGLAVFTLASLGCALSRSVEWLIAMRVLQGLGGAAMLSIA 129 TL FAAL LG+R GL +FT ASL CA + S+ L+ R QG+G +A++ + Sbjct: 81 ATLLPFAALGEILGYRRIAIFGLLLFTAASLACAYAWSLPTLVIARFFQGVGASAIMGVN 140 Query: 130 PAIHRTVFPNRLLGRILGLNAVLVAAGTAVGPVLGGTLLAALSWEWIFLINLPLGMVGVL 189 A+ R+++P R+LGR LG NA++VA AVGP +L+ SW W+F IN+PLG+ Sbjct: 141 TALLRSIYPARMLGRGLGTNALVVAVAFAVGPTTASLILSVWSWPWLFAINVPLGLFAYF 200 Query: 190 LAWSAIPETRKPARARFDIAGACWSALAMGALIMAADTCARLAEPGQGTQATLQAAAYAL 249 LA +P T++ A +FD A ++A G LI+A A L++ A Sbjct: 201 LARKVLPHTKR-ATHKFDALTAIYNAGGFGLLILAIGEGAHLSD-----------AKTVA 248 Query: 250 VALLAALAF----VRGQRRAPEPLLPLDIFANARFSLAALTSLVSFVGQGIAFVALPFLF 305 + L AL F +R Q+ P+LP+D+F F+L+ALT++ +F Q +AFV+LPF F Sbjct: 249 LELFGALVFFILLLRRQKGHAAPMLPVDLFRRPLFTLSALTAVCTFAAQSLAFVSLPFYF 308 Query: 306 QNGYGYSAFESAALFTPWPLGIVLVAPHAGRLADRHSPALLSSLGLALFTVGLALLALLP 365 + G SA E+ L TPW + + ++AP AGRL+D + P +L +GL++ + G+ L L+ Sbjct: 309 ETVLGRSAIETGFLITPWAVMVGIMAPIAGRLSDHYPPGMLGGVGLSVLSAGMVSLILMS 368 Query: 366 AHAQAWDIGWRALVCGMGFGFFQSPNNREMLGNVSRERSGNASGVLAIMRTFGQCLGAAL 425 + I WR +CG+GFGFFQ+PN R ++ + ER G+ASGV+A R GQ GAAL Sbjct: 369 PDVSVFGICWRMALCGIGFGFFQAPNLRAIMSSAPPERGGSASGVVATSRLLGQASGAAL 428 Query: 426 LGMILAIYTAH 436 + I T H Sbjct: 429 VAFCFIISTQH 439 >gi|152982562|ref|YP_001352191.1| major facilitator superfamily drug efflux transporter [Janthinobacterium sp. Marseille] Length = 518 Score = 114 bits (284), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 122/424 (28%), Positives = 191/424 (45%), Gaps = 14/424 (3%) Query: 13 LPGQQRRRAMLAVMTATTMAVFDGTIINVALPQISLALHTSAAASVWVANAYLLATAMTL 72 LP R + V A + V D T++ ALP+++ L SA+A +W+ N Y L + L Sbjct: 15 LPSSSRWLVLAIVSVALLLIVVDMTVLYAALPRLTADLTASASAKLWIVNIYALTVSGLL 74 Query: 73 AVFAALSSRLGFRTQFTAGLAVFTLASLGCALSRSVEWLIAMRVLQGLGGAAMLSIAPAI 132 L RLG ++ F AGL VF +ASL A S S LIA R L +G A M+ +I Sbjct: 75 LGMGTLGDRLGHKSLFIAGLVVFGIASLCAAYSPSSATLIASRALLAVGAAMMMPATLSI 134 Query: 133 HRTVFPNRLLGRI-LGLNAVLVAAGTAVGPVLGGTLLAALSWEWIFLINLPLGMVGVLLA 191 R F + + +G+ A + G A+GPV+GG LL W +FLIN+P+ +V + +A Sbjct: 135 IRLAFADENERAVAIGIWASVAFGGAALGPVVGGLLLEYFWWGSVFLINVPIVLVALPIA 194 Query: 192 WSAIPETRKPARARFDIAGACWSALAMGALIMAADTCARLAEPGQGTQATLQAAAYALVA 251 + IP+ + +D+ G S M L+ L E G+ A A LV Sbjct: 195 LAYIPKGKANKTRPWDLIG---SLQIMAGLV---GVTYALKEAGKREPAWGIALLVLLVG 248 Query: 252 LLAALAFVRGQRRAPEPLLPLDIFANARF---SLAALTSLVSFVGQGIAFVALPFLFQNG 308 + F R Q+ + P++ +F N F AA+ + + +G + F Q Sbjct: 249 IFFLAVFARRQQHSAHPMIDFSLFKNTIFSSSVAAAVVAAAALLGMELVFTQ---RLQLV 305 Query: 309 YGYSAFESAALFTPWPLGIVLVAPHAGRLADRHSPALLSSLGLALFTVGLALLALLPAHA 368 + ++ P L + P GR+ R A + SL L + +G+ L A Sbjct: 306 LDMTPLQAGVFILPLSLAAFVAGPLTGRVLPRLGSAYVLSLSLLISGLGMGAYLFL-YDA 364 Query: 369 QAWDIGWRALVCGMGFGFFQSPNNREMLGNVSRERSGNASGVLAIMRTFGQCLGAALLGM 428 AW LV G G G + + ++ + +R+G A+ V + G G L+G Sbjct: 365 AAWIQIICLLVLGAGIGAAMTAASGTIMQSAPVDRAGMAASVEEVSYELGSVFGVTLMGS 424 Query: 429 ILAI 432 IL++ Sbjct: 425 ILSL 428 >gi|152982589|ref|YP_001352814.1| major facilitator superfamily multidrug resistance B translocase [Janthinobacterium sp. Marseille] Length = 517 Score = 109 bits (272), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 93/338 (27%), Positives = 157/338 (46%), Gaps = 12/338 (3%) Query: 23 LAVMTATTMAVFDGTIINVALPQISLALHTSAAASVWVANAYLLATAMTLAVFAALSSRL 82 LA+ A M V D +I NV++P IS L S WV ++ +A A+++ + L+ R+ Sbjct: 22 LALSLAVFMNVLDSSIANVSIPAISGDLGVSPQQGTWVITSFSVANAISVPLTGWLTQRI 81 Query: 83 GFRTQFTAGLAVFTLASLGCALSRSVEWLIAMRVLQGLGGAAMLSIAPAIHRTVFPNRLL 142 G F + +F LAS C + S+E LIA RVLQG M+ ++ A+ + +P Sbjct: 82 GQVRLFIGSILLFVLASCLCGFAPSIEILIAARVLQGAVAGPMIPLSQALLLSSYPPAKS 141 Query: 143 GRILGLNAVLVAAGTAVGPVLGGTLLAALSWEWIFLINLPLGMVGVLLAWSAIPETR-KP 201 G L + +GP+LGG + +W WIF IN+P+G+ WS E + Sbjct: 142 GMALAFWGMTTLVAPIMGPLLGGWISDNYTWPWIFFINIPIGLFAAWATWSIYKERESRT 201 Query: 202 ARARFDIAGACWSALAMGALIMAADTCARLAEPGQGTQATLQAAAYALVALLAALAFVRG 261 + D G L +G+L + D L G L A VA++A + FV Sbjct: 202 YKLPIDKVGLVLLVLWVGSLQLMLDKGKELDWFHSGEIIIL-----ASVAVVAFIYFVIW 256 Query: 262 QRRAPEPLLPLDIFANARFSLAALTSLVSFVGQGIAF---VALPFLFQNGYGYSAFESAA 318 + P++ L +F FS + V++ G+ F V LP Q GY+A E+ Sbjct: 257 EIGEEHPVVDLSLFKGRNFSGGVIAISVAY---GLFFGSLVILPLWLQTQIGYTATEAGK 313 Query: 319 LFTPWPLGIVLVAPHAGRLADRHSPALLSSLGLALFTV 356 + P + ++++P G++ + +++ +F++ Sbjct: 314 VMAPVGIFAIILSPIVGKMLPKIDARWVATTAFLIFSL 351 >gi|152982526|ref|YP_001355122.1| major facilitator superfamily drug efflux transporter [Janthinobacterium sp. Marseille] Length = 481 Score = 108 bits (270), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 100/417 (23%), Positives = 188/417 (45%), Gaps = 22/417 (5%) Query: 22 MLAVMTATTMAVFDGTIINVALPQISLALHTSAAASVWVANAYLLATAMTLAVFAALSSR 81 +L M + A+ TI+NVA+P +S + WV+ ++LA +++ + L R Sbjct: 22 LLTCMIGSVAAILSSTIVNVAIPDLSRYFVLGQERAQWVSTGFMLAMTLSMLLTPWLLLR 81 Query: 82 LGFRTQFTAGLAVFTLASLGCALSRSVEWLIAMRVLQGLGGAAMLSIAPAIHRTVFPNRL 141 G R + + + + + S + L++MRVL+GL M I + F Sbjct: 82 FGLRRTYGGAICLLLIGGVVGGFSINYPMLLSMRVLEGLASGVMQPIPAIVILRAFDQHE 141 Query: 142 LGRILGLNAVLVAAGTAVGPVLGGTLLAALSWEWIFLINLPLGMVGV------LLAWSAI 195 G+ +G+ V AVGP +GG L+ W IF + +P +V + L +++ + Sbjct: 142 QGKAMGIFGFGVVLAPAVGPSVGGFLVELFGWRSIFFVVVPPCLVVLVLIQRFLASYTPV 201 Query: 196 PETRKPARARFDIAGACWSALAMGALIMAADTCARLAEPGQGTQATLQAAAYALVALLAA 255 P++ KP W G L++ + L + QA ++ + Sbjct: 202 PDSDKPLD---------WK----GLLLIGVSIVSLLNGVVELRGDMPQAVVLLVIGVATL 248 Query: 256 LAFVRGQ-RRAPEPLLPLDIFANARFSLAALTSLVSFVGQGIAFVALPFLFQNGYGYSAF 314 + F+ Q R + EPL+ + +F + +F++ AL + + +G + LP Q G Y+ Sbjct: 249 IGFILYQTRTSAEPLMNMQLFRHRQFAMGALVAFIYGMGLFGSTYLLPIYMQMGMNYAPS 308 Query: 315 ESAALFTPWPLGIVLVAPHAGRLADRHSPALLSSLGLALFTVGLALLAL-LPAHAQAWDI 373 ++ + P + + + P AGRLADR+ P +L ++GL L AL+A PA + + Sbjct: 309 QAGLVLLPAGIVLAVTIPLAGRLADRYPPNVLVAIGLFLLAASFALMANGSPATSYLALM 368 Query: 374 GWRALVCGMGFGFFQSPNNREMLGNVSRERSGNASGVLAIMRTFGQCLGAALLGMIL 430 W A++ +G GF + + + + + +R G +G +L+G++L Sbjct: 369 AW-AVIGRIGLGFVLPALSLGAMRGLDIGLVAQGASAINFVRQLGGAIGVSLVGVVL 424 >gi|152980367|ref|YP_001352036.1| major facilitator superfamily drug efflux transporter [Janthinobacterium sp. Marseille] Length = 478 Score = 102 bits (254), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 75/284 (26%), Positives = 137/284 (48%), Gaps = 14/284 (4%) Query: 16 QQRRRAMLAVMTATTMAVFDGTIINVALPQISLALHTSAAASVWVANAYLLATAMTLAVF 75 + +R V A M D TIIN A+P ++ +LH + + V ++Y+LA A+++ + Sbjct: 15 KVKRYLPWVVAIALFMEQLDSTIINTAIPSMAASLHVTPLSLKAVVSSYILALAVSIPIS 74 Query: 76 AALSSRLGFRTQFTAGLAVFTLASLGCALSRSVEWLIAMRVLQGLGGAAMLSIAPAIHRT 135 ++ R G R F+ + +FT +S+ C LS +V L+A R+LQG A M+ + Sbjct: 75 GWMADRFGTRRVFSVAVGLFTFSSILCGLSVNVPMLVAARILQGFSAAMMMPVGRLTVIR 134 Query: 136 VFPNRLLGRILGLNAVLVAA--GTAVGPVLGGTLLAALSWEWIFLINLPLGMVGVLLAWS 193 FP L + +N V++ A G +GP +GG ++ L W+ IF +N+P+G+ + Sbjct: 135 TFPKSEL--LAAMNFVIIPALIGPLLGPTVGGLIVHWLPWQAIFFVNVPIGLAAQWMIHR 192 Query: 194 AIPETRKPARARFDIAGACW--SALAMGALIMAADTCARLAEPGQGTQATLQAAAYALVA 251 +P+ R + D+ G S +A+ + I+ G+ +++ Sbjct: 193 HMPDYRSDSPRPLDVIGLVLFGSGVALLSWILEIF--------GEHYLDATSTTILFIIS 244 Query: 252 LLAALAFVRGQRRAPEPLLPLDIFANARFSLAALTSLVSFVGQG 295 L A++ RR PLL L +F F ++ + ++ +G G Sbjct: 245 LALLGAYILHARRTLHPLLQLTLFKTRTFRVSVVGGFITRLGVG 288 Database: BlastDatabases/707/707 Posted date: Apr 13, 2011 12:58 PM Number of letters in database: 1,221,021 Number of sequences in database: 3697 Lambda K H 0.325 0.135 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 3697 Number of Hits to DB: 941,240 Number of extensions: 35441 Number of successful extensions: 226 Number of sequences better than 1.0e-08: 11 Number of HSP's gapped: 219 Number of HSP's successfully gapped: 11 Length of query: 484 Length of database: 1,221,021 Length adjustment: 87 Effective length of query: 397 Effective length of database: 899,382 Effective search space: 357054654 Effective search space used: 357054654 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 131 (55.1 bits)