BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2225.p (3675 letters) Database: BlastDatabases/689/689 4735 sequences; 1,619,870 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|300311658|ref|YP_003775750.1| non-ribosomal peptide synthetas... 2176 0.0 gi|300312041|ref|YP_003776133.1| acyl-CoA synthetase/AMP-acid li... 157 1e-38 gi|300309365|ref|YP_003773457.1| acetyl-coenzyme A synthetase [H... 126 3e-29 gi|300313157|ref|YP_003777249.1| long-chain-fatty-acid-CoA ligas... 95 1e-19 gi|300310257|ref|YP_003774349.1| acetyl-coenzyme A synthetase [H... 91 2e-18 >gi|300311658|ref|YP_003775750.1| non-ribosomal peptide synthetase [Herbaspirillum seropedicae SmR1] Length = 9160 Score = 2176 bits (5639), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1546/3752 (41%), Positives = 2022/3752 (53%), Gaps = 234/3752 (6%) Query: 45 TRAPGTPAPLSFAQQRLWYLWKLTPQSSAYHLAGGLRLQGPLEAAALERAVDALALHHPA 104 +R P APLS++QQ+LW+L + P +AY+L RL G L+ AAL A+DAL H Sbjct: 5191 SRPPHEHAPLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAI 5250 Query: 105 LRTVLREDADGNVTQTVLPACAWSLSRQDLSLLPAHRRQDALREQVQRLCSRPFELDGGA 164 LRT E DG Q +P L+ DL LP +R+ L+E++Q + F+L Sbjct: 5251 LRTRFAE-TDGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAG 5309 Query: 165 LVRACLLQVDEQEHQLIVVMHHIISDAQSTQLILAELLALY-QAARQGQAISAAWHGPDL 223 + L+ + QEH L++ MHHI+SDA S L++ +L Y QA R GQA A Sbjct: 5310 QLDVRLIALGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPM-QY 5368 Query: 224 GDYAVWQRQCLNSTQAERQLAWWKAQLGNSSPVLELPTDHARRPDGQYGAASWRIVLEPA 283 DYA WQRQ + +L +W LG + L+LPTD R + A L+ A Sbjct: 5369 ADYAHWQRQRVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSA 5428 Query: 284 LLDALRRRAQGQGCSLFVVLLCAFQALLYRHTSQRDVRVGVPVSHRLRSELAAAVGFFVD 343 L ++ + Q C+ FV L+ A+Q LL R++ Q D VG P + R +EL VGFFV Sbjct: 5429 LAQQMQAFCRAQHCTPFVALMAAWQVLLSRYSGQSDFLVGAPNAGRNHAELQDLVGFFVT 5488 Query: 344 TQVLRAELAGQTTLESLLAQVRDTSFAAQAHRDIPLERLVEVLQPERSIGRTPLFQVMFN 403 TQ+ RA L + T+ L+ QVR AA H D+P E L+E + ER GR PLFQVMF Sbjct: 5489 TQLYRARLTPELTVRELVRQVRGDMLAALEHGDLPFEALLEHRKVERDPGRNPLFQVMFG 5548 Query: 404 -HLREQADGSQSWPGLSVQRLDFDAAVAQFELTLETSEEANGELSATFRYARELFDESSI 462 + + + ++ + L A+F+L+L+ + GE+ YA +LFD ++I Sbjct: 5549 LQMVGEGASALAFDDIVTAPLPLAQDSAKFDLSLDV-KVIKGEVHCRLEYASDLFDAATI 5607 Query: 463 ARMAQHYVAILQALATQPQLRVAELQLRGAEEDRQLHSWGVNNEQHAEVMEPVHEQ---- 518 A MA HY +L+ A P+ VA+L L +E +L SWG + Q E + P Sbjct: 5608 AAMAGHYRNLLRGFAEAPERPVAQLALLDQDEQARLRSWG--DPQLREALPPTSSASLAG 5665 Query: 519 -IARQARRQPEATALLFGRQQLSYGALERRANQLAHRLIRLGAGPEVKVGIAVERSLEMV 577 I QA P+A A++ G QQ+SY L R AN+LAHRL++ G G E ++G+A RSLEM+ Sbjct: 5666 LIEAQAAAIPDAVAVVCGPQQMSYAQLNRAANRLAHRLLQQGVGLEDRIGLAAPRSLEMI 5725 Query: 578 IGLLGILKAGAAYVPLDPEYPAQRLQYMMQDSGMRLLLTQQHVLPTLPPLAGLPVLALDQ 637 +GLL ILKAGAAYVPLDP+YPA RL YM+Q + + + P + Sbjct: 5726 VGLLAILKAGAAYVPLDPDYPADRLAYMVQACRRHPGVDGRARVSLPGPRKACAHWRSPR 5785 Query: 638 LDLDDEA-HQPPAVRVHGENLAYVIYTSGSTGQPKGVANRHCALRNRLAWMQQAYRLEPH 696 DD A P V +H +NLAY+IYTSGSTG+PKG H + L + Sbjct: 5786 PWADDAAPAHNPGVVLHPDNLAYIIYTSGSTGRPKGAQLSHANVLRLLGQTAAWFDFGRE 5845 Query: 697 DTVLQKTPFSFDVSVWEFFWPLMIGARLALAQPGDHRDPARLVEQIQRHAVSTLHFVPSM 756 D ++FD SVWE F L G RL + R P + + V+ L+ PS Sbjct: 5846 DVWTLFHSYAFDFSVWEIFGALCYGGRLVVVPFAVSRSPEDFLALLVEQRVTVLNQTPSA 5905 Query: 757 LQAFLAHDEIEGCSS----LHRLICSGEALPVEAQQGVFARL--PQVALYNLYGPTEAAI 810 + L + S L +I GEAL E + + + AL N+YG TE + Sbjct: 5906 FRQLLQLPALRQLPSEALALRTVIFGGEALEPEMLRPWITQFGDQRPALINMYGITETTV 5965 Query: 811 DVTHWTC-RAD-GRSQVPIGRPISSIRTLVLDGDLNLAPQGVPGELYLGGIGLARGYLGR 868 VT+ RAD S+ PIG I + VLD LNLAP GVPGELY+ G GLARGYL R Sbjct: 5966 HVTYRRLLRADLDASRSPIGAAIPDLGLYVLDQQLNLAPAGVPGELYVSGAGLARGYLNR 6025 Query: 869 AGLSAERFVADPFSADGE---RLYRTGDLVRWNREGQLDYLGRLDHQVKIRGLRIELGEI 925 A LSAERFVA+PF+ GE RLYRTGDLVRW +GQ+DYLGR+D QVKIRG RIELGEI Sbjct: 6026 AALSAERFVANPFARAGEEGSRLYRTGDLVRWRHDGQMDYLGRIDQQVKIRGFRIELGEI 6085 Query: 926 EARLLAQPGVREAVVVARESAGTSRLVAYVSGTDLVA------ATLRSALTKDLPDYMVP 979 EA+LLAQPGV A V+ R+ A T RLV Y+S +A LR+AL LPDYMVP Sbjct: 6086 EAQLLAQPGVGAATVMVRQDAATPRLVGYLSPQAGIAPEALDTGALRTALGAVLPDYMVP 6145 Query: 980 ALIEVLEHLPLNANGKVDRRALPDPAQPLQRAYEAPRGQAEQVLAAVWAEVLGLQQVGRH 1039 A + +L LPLN NGKVDR+ALP P + AY AP+G E+ LAA+W EVL VGR Sbjct: 6146 AALVMLPALPLNINGKVDRKALPAPELAARTAYAAPQGALEEQLAAIWREVLKGGAVGRD 6205 Query: 1040 DNFFELGGDSILSLQIVAGLRRRGSQLAPRLIFERQTIAQLAPAIAHST---APQLHAQV 1096 DNFFELGGDSILSLQIV+ RR G + R +FERQT+A+LA + + P+ Sbjct: 6206 DNFFELGGDSILSLQIVSRARRAGIAITARQMFERQTVAELAAVASEAVAAATPRAITHT 6265 Query: 1097 SVQGE-LPLLPIQAEFFAMDIPVRHHWNQSILLATDAPLDMAALNTALQAVVAHHDSLRL 1155 + G+ LLPIQ +FF DIP R HWNQS+LL +DAP+D AAL ALQA++ H +L + Sbjct: 6266 AQAGQACRLLPIQQDFFEADIPRRAHWNQSVLLHSDAPIDPAALAAALQALMQAHPALTM 6325 Query: 1156 RYTRDDQGQWRQTYGQHDPAQ-LRELLWVRQGLPGNAIAPLCEQAQRSLNLARGPLLRAV 1214 RY + G WRQ +G+ Q + E + + + LCE AQRSL+L G +LRAV Sbjct: 6326 RYAQHSDG-WRQLHGELPTLQAIAERIVSARAADAEQLLALCESAQRSLDLEHGLVLRAV 6384 Query: 1215 AMELEEGGWRLLLVIHHLVVDGVSWRILLADLQQAYRQCVAL--EPLVLPARTASYQQWA 1272 +++ + GWRLLLV HHLV+DGVSWR+LL DLQ AY A E LPA A +W Sbjct: 6385 LVDMGQAGWRLLLVAHHLVIDGVSWRVLLEDLQHAYAHACATPHEAPQLPAEEAGPAEWG 6444 Query: 1273 HVLQGRHGALLPQRPYWQAQMQPPSVLPCDDA-----GGEATMRQRQEMSFGLDKERTNA 1327 L + +W P LP D A G A + +Q + L T Sbjct: 6445 EALAAYAPVAAQRIDHWLGLAGCPVQLPSDPARAGEEGASARLVDQQSVLLRLTPALTQT 6504 Query: 1328 LLRRVPAAYRTRINDVLLTALVRALCGWSGLSEIQVDIEGHGRE---DGTGQLDLSRTVG 1384 L+ +A+RT++ND+LL AL RAL W + VD+EGHGRE DG DLSRTVG Sbjct: 6505 LIGEAHSAWRTQVNDLLLAALARALAAWGAPQPLLVDLEGHGREALGDGAATPDLSRTVG 6564 Query: 1385 WFTSVFPLRLSGAGTPQQALKRIKESLRAVPEAGLGFGLLRQAGN------LPGSSSSPV 1438 WFTSVFPL L +GTP L R KESLRA+P GL FG+LR+ G L + V Sbjct: 6565 WFTSVFPLALEASGTPLATLLRTKESLRALPNKGLDFGVLRRFGTAEQRAALQALPRAQV 6624 Query: 1439 IFNYLGQFDASFDGTSGWRPAQEESGAAIDPDAPMQHEFAVEGQVYDGQLLINVAYSGKR 1498 FNYLGQF + +G GWR A E +G +DP A M+H + GQV++G L + + Y KR Sbjct: 6625 AFNYLGQFQSGEEG--GWRLASESAGTPMDPQAAMRHALTINGQVHEGVLQLRLNYCSKR 6682 Query: 1499 YARASVQAWVERFEQELDALITHCTSGACGATPSDFPLAGLDQTAIDQLGVSLADVADLY 1558 Y RA V+ + +L+ L C+ A G TPSD PLAGLDQ +D L ++ +V D+Y Sbjct: 6683 YGRAMVETLAAHLQAQLEELAALCSQHAGGLTPSDLPLAGLDQAQLDALPLAARNVDDIY 6742 Query: 1559 PLSPMQSGMLFHSVSEPDNAAYTMQMQVALEALQPERFRAAWQAVLDRHAILRSAILQRD 1618 PLSPMQ+GMLFHSV EP +AY Q++V ++ L RF AWQ + H ILR+ L + Sbjct: 6743 PLSPMQAGMLFHSVFEPGGSAYINQLRVDIDGLDAARFEQAWQDTVAAHDILRTGFLHQP 6802 Query: 1619 DAPLQWVARRVVLPWQ---LRDCRHSPDLAAELDELARREREAGFDLARPPLMRLMLVST 1675 PLQWVARRV P RD L ELD LA+R+ GFDLA PPLMRL+LV T Sbjct: 6803 R-PLQWVARRVASPLSQLDWRDAAAGQSLGGELDALAQRQLAQGFDLAAPPLMRLVLVRT 6861 Query: 1676 GEQGYHLIWTVHHLLLDGWSTSQLLGEVLRHY-----AGQTLDEPVA-AYGDYIRWLQGR 1729 G Q +HLIWTVHHLLLDGWSTS LLGEVLR Y AGQ +A Y DYI WLQGR Sbjct: 6862 GAQRHHLIWTVHHLLLDGWSTSMLLGEVLRRYAQATAAGQAKPTKLALRYRDYIGWLQGR 6921 Query: 1730 DQQASRHHWQSLLHRLQEPSLLVARLPPAKQPNRARDYRQYTCCLGQAQTRRLVEFARAR 1789 DQ+A+R W+ L RLQ+P+ L +P P + ++ L A T RL E ARA+ Sbjct: 6922 DQEATRRFWEIQLARLQQPTRLADAMPRPSTPESG--HGEHRELLDAALTARLNEAARAQ 6979 Query: 1790 HLTLSTLVQAAWALLLQR--YAGHGT-VCFGATTAGRPMDLAGAESMLGLFINTLPVVTT 1846 +TL+TLVQAAWALLLQR YA H V FGAT AGRP +L G E +LGLFINTLPV+ Sbjct: 6980 RITLNTLVQAAWALLLQRYTYAAHDQGVVFGATVAGRPAELTGVEQLLGLFINTLPVIVA 7039 Query: 1847 LTPQTALDEWLQQLQRQSAQSREHEYTPLYEIQRLAGHSGQSLFDTVVVFENYPVDAALH 1906 P +W++ LQ Q+ Q+RE+E+TPL +IQR +G Q+LFD+++VFENYPVDA L Sbjct: 7040 TPPHQPAGDWMRALQAQNLQAREYEHTPLVDIQRWSGQGAQALFDSILVFENYPVDATLS 7099 Query: 1907 SQEVDKLVVGEVRFSSGNHYPLTLRVSLAEQLQIDFLHDTGMIAPELLARMAAQFTSLLE 1966 L VR +YP+T+ V+ + LQ+ + A E++ R+ A LL+ Sbjct: 7100 QGAPAGLAFSSVRHREETNYPMTVVVNAGDTLQLQLRYARAQFAHEMVERIGAHLRHLLQ 7159 Query: 1967 QFSQ--------------DDGETRRRRLADLSLTDLPAPLQGPTIRADDVIERWAAQVSQ 2012 ++ D+ R + L AP+ +IER Q + Sbjct: 7160 VLAEHPQQAIGSLGLLPGDELAAWRESGVNRELHAFDAPVH-------RLIER---QAAA 7209 Query: 2013 QPGAAALTDGNHALDMAGLCAWVEQMAQQMRQRGIGCEDRVAIHAERSCAFVVAVLATLR 2072 P AAAL + LD L ++A ++ G G E V + A R+ VVA+LA L+ Sbjct: 7210 TPSAAALLYEDLVLDYRSLNQQANRLAHRLLAEGAGPERIVGVAARRAPEMVVALLAVLK 7269 Query: 2073 VGAAYVPLDPALPAERLHYQLQDSAAVLLLSATA----PDWAASVPVLPLAS-----LHG 2123 GAAY+PLDP LP RL + DS LLL+ TA A+V VL L + G Sbjct: 7270 AGAAYLPLDPDLPPARLADMMADSGLSLLLTQTALRAELTAPAAVRVLELDAPGQPWAEG 7329 Query: 2124 VPKRVPYCWPAVHPGQAAYVIYTSGSTGRPKGVVVSRGALANYVAGVLERLDLREQDRSM 2183 +P P V P AYVIYTSGSTG+PKG +L N +A + E + + ++ Sbjct: 7330 MPDHDPGI--EVAPDGLAYVIYTSGSTGKPKGAGNRHVSLHNRLAWMQEAYPIGPGN-TV 7386 Query: 2184 AMVSTVGADLGHTVLFGALCSGRLLHLIPPQCSFDPDAMASYMEQHQVDVLKIVPSHLQA 2243 + G D+ F L +G L L P DP +A+ + +H VD L VPS LQ Sbjct: 7387 LQKTPFGFDVSVWEFFWPLMTGARLALAAPDEHRDPALLAARIRRHAVDTLHFVPSMLQG 7446 Query: 2244 LLHAASPASVLPRSRLVLGGEASRKPLLAHIASLRPQCRVMNHYGPTETTVGVLTQEASS 2303 + A +++ GEA L + PQ + N YGPTE + V Sbjct: 7447 FVAHPDSAQCHSLRQVICSGEALPAELQEQAFARLPQIALHNLYGPTEAAIDVTHWTCRP 7506 Query: 2304 ALDEADSLPIGQPIAQARAYVLDAELQPVPQGVAGELYLAGHGVARAYQQRPAQSAERFV 2363 S+PIG+PI+ AYVLD L P+P G+AGELYL G G+AR Y RP SAERFV Sbjct: 7507 G---ERSVPIGRPISHTAAYVLDGGLNPLPHGIAGELYLGGIGLARGYLGRPGLSAERFV 7563 Query: 2364 AD-LLEPGQRMYRSGDRVRQLADGSLEFLGRLDGQIKVRGYRVELREIAALLQSLEAVAQ 2422 AD G RMYR+GD VR+ ADG +E+LGR D Q+K+RG R+EL EI A L + VA Sbjct: 7564 ADPFAADGSRMYRTGDLVRRRADGEIEYLGRTDHQVKIRGLRIELGEIEAQLLAQPGVAA 7623 Query: 2423 AEVVVHSEPAQPGPDGEEVAPQIIAYLVPMGGQTLDVADLRQQLATRLPDYMMPTALVPL 2482 A VV EP +P +++ Y GG L+ LR L LPDYM+P L+ L Sbjct: 7624 AVVVALVEPGRPA--------RLVGYAADPGG-MLEAEALRAALLQSLPDYMVPQRLILL 7674 Query: 2483 HVMPLTPNGKLDRQALPRPDSTATSVYEAARGPLEETLAGLWAELLGLPQVGRNDDFFAL 2542 +PL NGK+DR+ALPRPD YEA +G E LA +WAE+L L +VGR+D+FF L Sbjct: 7675 PALPLNANGKVDRKALPRPDFNEQGGYEAPQGQTEIGLAAIWAEVLRLQRVGRHDNFFEL 7734 Query: 2543 GGDSILVLKLVARARKRDVKLAPKMLFEGKTPAGVA------------QLLTAGSG---- 2586 GGDSIL L++VARA ++ L P+ LF+ +T A +A Q +TA G Sbjct: 7735 GGDSILSLQIVARAHEQGWPLTPRQLFQSQTVAELAQQCDQLQPPAPTQAVTAARGRLED 7794 Query: 2587 -----------AAGGVERIMPLPPAQRNGLLPASYAQARQWFLWQLDPGSSAYHINGALR 2635 G +E + PL P Q+ L F PGS Y ++R Sbjct: 7795 YLSAAQTAQLALQGELEDVYPLSPMQQGML-----------FHTMESPGSGLYVNQLSVR 7843 Query: 2636 LCGTLDEAALEQAFSRLLERHPSLRTVLRADAD-GQVLQWVQPHACLAFKRIDLEPLAEG 2694 + G LDEA QA+ +L RHP +RT AD Q LQ V + D A Sbjct: 7844 VEG-LDEARFAQAWQSVLARHPVMRTGFLWQADYAQPLQAVWRTLAFGIEVQDWSARATM 7902 Query: 2695 PR-------QARLHAEVASLCRQPFDLEAGPLLRIGLLRESGHRHVLVMVMHHIISDGWS 2747 P R AS C PL+R LLR +H LV MHHI+ DGWS Sbjct: 7903 PSCRRRLPPLRRPILRAASTCCN------RPLVRATLLRLGPGQHQLVWTMHHILLDGWS 7956 Query: 2748 MQLIMDEFASLYGACCQGREAGLPALPLQYADYAAWQRQWMQGGQRETQLRYWQDHL-GQ 2806 +M E YG LPA YA Y W+ + RYW L Sbjct: 7957 TSALMQELMLAYGG------QPLPAPGPDYAQYIG----WLATLDPQAAQRYWMGALQAL 8006 Query: 2807 SQPSLLLPADHP---RRPDG-LYRAARHEAVLPPPLVAALRQRVQSDGGTLFAVLLAAAQ 2862 PSLL P RR G LY A L Q +S TL ++ A Sbjct: 8007 DGPSLLAEGVRPDPARRGFGKLYGHCDAAA------TRRLEQFARSQRVTLNTLVQGAWS 8060 Query: 2863 LLMYRYSGQNDIRLGVPIANR--HLPDTEGVVGFFVNTQVLRAEIDPRQSLARLVQLTRE 2920 L + R+ + G ++ R LP E +G F+NT + E+D ++ + ++ ++ Sbjct: 8061 LALARHKRSTAVAFGATVSGRPAALPGVEKSLGLFINTIPIVVEVDGQRRVGDWLRTLQQ 8120 Query: 2921 TAQGAQQHQDLPFEQLVEVLQPQRLVGV--NPLFQVMFNHQRHARPTSHQL---PQLTLE 2975 T +++H+ P + QR G+ LF + + P S L Q L Sbjct: 8121 TNIDSREHEHTPLYDI------QRWSGMAGRALFDSIIVFENF--PISRSLEARAQAGLR 8172 Query: 2976 PFELEEQDAQFELAIDTLEDTDGGLSVSLTYARELFEPQTMATMASHYLVALEALASQPQ 3035 F E + A+D L + Y R LF + + ++ L+AL++ + Sbjct: 8173 -FGQAEGEGLTGFAMDLQVVARETLDIEFCYDRSLFGDAEVEALREQVMLNLDALSASGE 8231 Query: 3036 CRVGEIDWLGPAERSRLAAWGDKVSPYATPAVITTRIAQRASIQPDAVALISGNRSMSYG 3095 +GE+ L P + + G Y IAQRA+ PDA+AL+ +S+SYG Sbjct: 8232 RALGELARLSPQALAAVLELGRGAHDYPADLPAHLLIAQRAAQTPDAIALVLEEQSLSYG 8291 Query: 3096 QLNTRVNQLAHYLLQRGLQPEARVGVALERSADMVVAVLAILKAGATYVPLDPDYPVQRL 3155 +LN R N+LAH+L+ G+ E RVGVA+ERS DMVV +LA++KAGA YVPLD DYP +RL Sbjct: 8292 ELNVRANRLAHHLMSLGVGAEQRVGVAVERSFDMVVGLLAVMKAGAAYVPLDLDYPPERL 8351 Query: 3156 AAIIEDSALSLLLSQTSVSQRLPGGRAEQTLYLDQLDLQAQ-------PHDEPDVTIHSD 3208 A ++ DS + +LL+ ++RL +A+ L LD P +P V + Sbjct: 8352 AYMVADSRIRVLLTHAR-ARRLLAAQAQPGLRCLALDDADLAAQLAGLPAHDPVVAVAPQ 8410 Query: 3209 SLAYVIYTSGSTGRPKGVGISHRCLMEHGQIAADFFGLTPQDCMLQFSTLNFDGCIEQLF 3268 +AYVIYTSGSTG+PKGV +SH L+ H Q A + +TPQ LQF + +FDG E+ Sbjct: 8411 QMAYVIYTSGSTGQPKGVAVSHGPLVMHCQATAALYEMTPQWRELQFMSFSFDGAHERWI 8470 Query: 3269 PPLLVGAAVVLRGPELWDSQRLHVELLAHRISVLDLTTAYWLLLVQDFARMGVPDYGVLR 3328 L+ GAA+VLRGPE+W ++ L R+S AY L Q + G D L Sbjct: 8471 TTLISGAALVLRGPEMWSIEQSWQALHQQRVSNAVFPPAYLGQLAQWGEQHG--DAPPLE 8528 Query: 3329 RVHVGGEAMPPEGIKAWRDAGLAQVELFNTYGPTEATVTASILSCAPYVSGQTVLPAQMP 3388 GGEAMP + R LA L N YGPTE VT I +G +P Sbjct: 8529 LYVFGGEAMPRASFERVRRH-LAPRLLINGYGPTETVVTPLIWK-GTSAAGVDFDGPFVP 8586 Query: 3389 IGAPLAGRKLRVLDAELSPLPIGVAGELCIGGELLARGYLNQPGLSAERFVADPLGDGGA 3448 IG P+ R +LDA L P+ G AGEL IGG+ LARGYL +P SAERFVADP G+ GA Sbjct: 8587 IGKPVGRRNAYILDACLQPVAPGEAGELYIGGDGLARGYLERPAQSAERFVADPFGEPGA 8646 Query: 3449 RLYRTGDLVRWTHAGQLEYLGRIDHQVKIRGFRIEMGEIESIMLAQPEVREAVVVAR-EG 3507 R+YRTGDL RW G +EYLGR+DHQVKIRGFRIE+GEIE+++ QP V EA VV R +G Sbjct: 8647 RMYRTGDLARWLPDGNVEYLGRLDHQVKIRGFRIELGEIEALLRRQPGVAEAAVVVRSDG 8706 Query: 3508 VGS---LQLVAYV-TPQHGRHIETAE------LRECLVRHLPDYMVPAALVVLPALPLNA 3557 G QLVAYV PQ ETA+ LR L LP+YM+PA V+L ALP+ Sbjct: 8707 QGEETVRQLVAYVGAPQAVAAPETAQRDFSDSLRAALRAGLPEYMLPAHFVLLAALPVTH 8766 Query: 3558 NGKVDRKALPEPVYESRTGHEPPQGECEQALAAIWAEVLGLPAVGRHDNFFELGGHSLSI 3617 NGK+DRKALP P + P QALA IW VL VG+ DNFFELGG SL Sbjct: 8767 NGKLDRKALPAPQAAPARSYVAPATPAAQALAEIWQTVLKRERVGQEDNFFELGGDSLLC 8826 Query: 3618 LRI--QSRIQQQFPASALPLRSHFDHPTIAAF 3647 L++ ++R Q+Q+ + L PTIAA Sbjct: 8827 LQVIARARGQRQWNFN-FKLADLMQRPTIAAL 8857 Score = 1484 bits (3841), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1150/3101 (37%), Positives = 1587/3101 (51%), Gaps = 215/3101 (6%) Query: 53 PLSFAQQRLWYLWKLTPQSSAYHLAGGLRLQGPLEAAALERAVDALALHHPALRTV--LR 110 PL+ AQQ LW W+L P S+AY+LAG L L+G L+ ALE A+ LA H ALRT+ LR Sbjct: 692 PLTQAQQGLWLTWQLQPDSAAYNLAGVLDLRGELQVEALEDALCDLAARHAALRTLFPLR 751 Query: 111 EDADGNVTQTVLP--ACAWSLSRQDLSLLPAHRRQDALREQVQRLCSRPFELDGGALVRA 168 DG Q VL L R DL PA +R A +QR ++ F LD +RA Sbjct: 752 ---DGTPVQQVLDIDEARPMLLRSDLRRQPADKRAQAAASALQRFHAQAFRLDSETPLRA 808 Query: 169 CLLQVDEQEHQLIVVMHHIISDAQSTQLILAELLALYQAARQGQAISAAWHGPDL--GDY 226 L+Q++ +L + +HHI +D S +IL EL A Y+A G A S W +L GDY Sbjct: 809 MLVQLEPHHFRLGLCIHHIAADGWSLGIILDELTAAYEARCAGAAPS--WPALELQPGDY 866 Query: 227 AVWQRQCL--NSTQAERQLAWWKAQLGNSSPVLELPTDHARRPDGQYGAASWRIVLEPAL 284 AVWQRQ S + +RQL +W+A+L + +L LPTD R+ G R L AL Sbjct: 867 AVWQRQRSQPGSPEFQRQLDYWRARLEGAPALLPLPTDRPRQAGAHGGEGQHRWRLSAAL 926 Query: 285 LDALRRRAQGQGCSLFVVLLCAFQALLYRHTSQRDVRVGVPVSHRLRSELAAAVGFFVDT 344 ALR+ A QG +L+ +L F L R + Q D+ VG P++ R R + A V + ++ Sbjct: 927 STALRKLAASQGVTLYGAVLALFTLALQRLSGQSDLCVGAPLADRRRRQTQALVAYLINV 986 Query: 345 QVLRAELAGQTTLESLLAQVRDTSFAAQAHRDIPLERLVEVLQPERSIGRTPLFQVMFNH 404 QV+R + ++ +L+ QV+ AQAH+D+PL+ L+ LQPER G PLFQV Sbjct: 987 QVVRTRIDERSDFLALMRQVQQAVQEAQAHQDLPLDALMSALQPERVAGANPLFQVKCT- 1045 Query: 405 LREQADGSQSWPGLSVQRLDFDA-AVAQFELTLETSEEANGELSATFRYARELFDESSIA 463 ++QA + G R++ A A + F+L+L+ ++ G + YA LFD ++A Sbjct: 1046 -QQQAIATVRRMGGLDMRVELQANAESHFDLSLDFTDADEG-IDILLAYAPALFDAETVA 1103 Query: 464 RMAQHYVAILQALATQPQLRVAELQLRGAEEDRQLHSWGVNNEQHAEVMEPVHEQIA--- 520 + +LQALA Q V + + ++ V++P + A Sbjct: 1104 ----GFAGLLQALAQQ----VVAAPALALADLQAFPPVSAADQ----VLQPAEDVAACWR 1151 Query: 521 RQARRQPEATALLFGRQQLSYGALERRANQLAHRLIRLGAGPEVKVGIAVERSLEMVIGL 580 RQA QP+A AL G Q +S + + + GAGPE +V + R ++ V G+ Sbjct: 1152 RQALAQPDAVALRCGAQFISTSSCCNGSMRWRSAWHAAGAGPESRVALYAGRDIDFVCGM 1211 Query: 581 LGILKAGAAYVPLDPEYPAQRLQYMMQDSGMRLLLTQQHVLPTLPPLAGLPVLALDQLDL 640 L +L GAAYVPLDP+ PA+RL + +QDSG R +L + P AG+P+L+L+ Sbjct: 1212 LAVLDTGAAYVPLDPQLPAERLAWQLQDSGARWVLHEGQSAPAWLAQAGVPLLSLEAAGT 1271 Query: 641 DDEAHQPPAVRVHGENLAYVIYTSGSTGQPKGVANRHCALRNRLAWMQQAYRL-EPHDTV 699 + P VH AY+IYTSGSTG+PKGV L N +A + + L ++ Sbjct: 1272 APASPWTP-FPVHPAQAAYLIYTSGSTGRPKGVLVTRGGLANYVAAVLEKLALPAAARSM 1330 Query: 700 LQKTPFSFDVSVWEFFWPLMIGARLALAQPGDHRDPARLVEQIQRHAVSTLHFVPSMLQA 759 + + D+ + L G +L L DP + HAV L VPS LQA Sbjct: 1331 AMISTVAADLGHTTLYGALCSGRQLHLITHDLAFDPDGFAAYLHEHAVDVLKIVPSHLQA 1390 Query: 760 FLAHDEIEGCSSLHRLICSGEALPVEAQQGVFARLPQVALYNLYGPTEAAIDV--THWTC 817 L E H L+ GEA + + A P + N YGP+E + V Sbjct: 1391 LLHAARPEQVLPRHTLVLGGEATGWPLLERIAALQPACRVLNHYGPSETTVGVLVQEAAS 1450 Query: 818 RADGRSQVPIGRPISSIRTLVLDGDLNLAPQGVPGELYLGGIGLARGYLGRAGLSAERFV 877 + + +P+G + ++ VLD L AP G GELYLGG GLARGY GRA L+AERFV Sbjct: 1451 ASRRAAVLPVGSALVGVQAWVLDRQLRRAPVGAVGELYLGGAGLARGYHGRAALTAERFV 1510 Query: 878 ADPFSADGERLYRTGDLVRWNREGQLDYLGRLDHQVKIRGLRIELGEIEARLLAQPGVRE 937 A PF A G+RLYR+GD R+ +G +++LGR+D QVKIRG R+E GE+ +LL GV + Sbjct: 1511 AHPF-ASGQRLYRSGDRARYLGDGSIEFLGRIDDQVKIRGHRVEPGEVRQQLLRLAGVVD 1569 Query: 938 AVVVARESAGTSR------LVAYVSGTDLVAATLRSALTKDLPDYMVPALIEVLEHLPLN 991 A V+A +A ++ + +G A R+ L DLPDY++P L V LPL Sbjct: 1570 AAVLALPAADDAQRLQLHGFIVCAAGAVADPAGWRATLAADLPDYLLPTLTPV-PALPLT 1628 Query: 992 ANGKVDRRALPDPAQPLQRAYE-------------APRGQAEQVLAAVWAEVLGLQQVGR 1038 ANGK+DR+AL A + AP+G+ E LAA+WAEVL L QVGR Sbjct: 1629 ANGKLDRQALAGLMAGAMAAPQQQVPQVQQAHQAGAPQGELEHKLAAIWAEVLKLPQVGR 1688 Query: 1039 HDNFFELGGDSILSLQIVAGLRRRGSQLAPRLIFERQTIAQLAPAIAHS---TAPQLHAQ 1095 DNFFELGGDSIL+L+IVA R+ G ++AP+ + E+QT+A + A A A A Sbjct: 1689 EDNFFELGGDSILTLKIVARARKEGLRIAPKAMMEKQTVAAIVAAGAVQGLLAATPAPAV 1748 Query: 1096 VSVQGELPLLPIQAEFFAMDIPVRHHWNQSILLATDAP-LDMAALNTALQAVVAHHDSLR 1154 V+ ++PL P+Q FF HWNQS+LL +AP LD L AL + H+SLR Sbjct: 1749 VAAPADIPLTPVQHWFFEQGFATPQHWNQSVLL--NAPGLDADVLRRALALLAQRHESLR 1806 Query: 1155 LRYTRDDQGQWRQTYGQHDPAQLRELLWVRQGLPGNAIAPLCEQAQRSLNLARGPLLRAV 1214 LR+ ++ GQWRQ G PA L L + G AIA E QRSL+LA+GPL+ A Sbjct: 1807 LRFVQEG-GQWRQRRG---PALLP--LEIIDGDEPGAIAAAGELVQRSLDLAQGPLMAAA 1860 Query: 1215 AMELEEGG--WRLLLVIHHLVVDGVSWRILLADLQQAYRQCV-ALEPLVLPARTASYQQW 1271 + L+ G RLLL HHLVVDGVSWR+LL DL Y P LP T Y W Sbjct: 1861 WIRLDAQGKQGRLLLAGHHLVVDGVSWRVLLDDLAGLYHTLQQGGTPAELPPATDLYT-W 1919 Query: 1272 AHVLQG--RHGALLPQRPYWQAQMQPPSVLPCDDAGGEATMRQRQEMSFGLDKERTNALL 1329 + L+ + A+ Q YW++ + P P DA R + F LD + T LL Sbjct: 1920 SQALRAHAQRPAVTDQLAYWRSVVDTPEP-PLADATANLAGRA-ADAGFVLDADVTARLL 1977 Query: 1330 R---RVPAAYRTRINDVLLTALVRALCGWSGLSEIQVDIEGHGREDGTGQLDLSRTVGWF 1386 A R D+LL L R LC WSG + ++EGHGRED G LD+SR GWF Sbjct: 1978 ALGAHADPAVRVAPQDLLLAVLARVLCDWSGRDSLLFELEGHGREDIPGGLDVSRATGWF 2037 Query: 1387 TSVFPLRLSGAGTPQQ---ALKRIKESLRAVPEAGLGFGLLR----QAGNLPGSSSSPVI 1439 T+++P+RL+ T AL+ ++ LRAVP GLG+GLLR Q L + + Sbjct: 2038 TALYPVRLAPGATSTSIPSALEAVRAQLRAVPANGLGYGLLRYLSGQGQELAQGAQPQIT 2097 Query: 1440 FNYLGQFDASFDGTSGWRPAQEESGAAIDPDAPMQHEFAVEGQVYDGQLLINVAYSGKRY 1499 FNYLG FD + +GW A E +GA D+ + F +V G+L Y + Sbjct: 2098 FNYLGHFDHRIE-PAGWTLADEYAGAQRAADSRRRCLFEAIARVQQGRLQWQWTYCKDLH 2156 Query: 1500 ARASVQAWVERFEQELDALITHCTSGACGATPSDFPLAGLDQTAIDQLGVSLADVADLYP 1559 A A ++A ER EL I + AG D Y Sbjct: 2157 AAAEMRALQERLRTELMRWIEALEA-----------RAGSDAA---------------YA 2190 Query: 1560 LSPMQSGMLFHSVSEPDNAAYTMQMQVALEALQPERFRAAWQAVLDRHAILRSAILQRDD 1619 LSPMQ+GM FHS + AY Q+++ L + R A W+ + RH ILR+ Q+ D Sbjct: 2191 LSPMQAGMFFHSSMNAGDGAYINQLRLDLAGVDEARLEAVWREAVRRHPILRTGFRQQGD 2250 Query: 1620 APLQWVARRVVLPWQLRDCR-------------HSPDLAAELDELARREREAGFDLARPP 1666 AP QWVA+ VL W++ D + +L+++A E GFDLA+P Sbjct: 2251 APEQWVAQ-PVLHWRVLDLSGQPPQQQAQQAQLEQLEQLEQLEQIAAAELARGFDLAQPG 2309 Query: 1667 LMRLMLVSTGEQGYHLIWTVHHLLLDGWSTSQLLGEVLRHYAGQTLDEPVAAYGDYIRWL 1726 LMRL+L GE +HLIWT HHLLLDGWS++QL E++R YAG+ + P AY YI WL Sbjct: 2310 LMRLVLAKMGEGRHHLIWTRHHLLLDGWSSAQLFAEIVRAYAGEEIAAPTLAYRHYIDWL 2369 Query: 1727 QGRDQQASRHHWQSLLHRLQEPSLLVARLPPAKQPNRARDYRQYTCCLGQAQTRRLVEFA 1786 Q RD A+R W++ L L+EP+LL LP ++ A + ++ + AQ + L + A Sbjct: 2370 QARDGAAARDFWRAQLQHLEEPTLLAGALPRPRE--DASGHAEHLAAISPAQWQALCQAA 2427 Query: 1787 RARHLTLSTLVQAAWALLLQRYAGHGTVCFGATTAGRPMDLAGAESMLGLFINTLPVVTT 1846 +A +T TL+Q AWAL+LQR G V FG T RP +L G ES LGLFINTLP+ Sbjct: 2428 KAMRITPGTLLQGAWALVLQRCCGQSAVAFGVTVVDRPAELEGIESTLGLFINTLPLAVR 2487 Query: 1847 LTPQTALDEWLQQLQRQSAQSREHEYTPLYEIQRLAGHSGQSLFDTVVVFENYPVDAALH 1906 L +WL+ L Q+ RE + PLYEIQR +G +GQ+LFD+++V ENYP+D A+ Sbjct: 2488 LHAAQDCSDWLRALLHQNLAMREFAHAPLYEIQRWSGRAGQALFDSILVLENYPMDEAIG 2547 Query: 1907 SQEVDKLVVGEVRFSSGNHYPLTLRVSLAEQLQIDFLHDTGMIAPELLARMAAQFTSLLE 1966 L + +R YPLT+ ++ + L + +D +A++A L Sbjct: 2548 RAADYGLHLSGLRLHEQTSYPLTVVATVQDGLSLRLGYDRSRFGAYQVAQLADWLAQALV 2607 Query: 1967 QFSQDDGETRRRRLADLSLTD-------LPAPLQGPTIRADDVIER-WAAQVSQQPGAAA 2018 + T RL D +L L L G + + R + Q S++P A A Sbjct: 2608 TLT-----TGGARLGDCALGSATQRQQALGWSLNGQRFDGQEPVHRLFEQQASRRPDAIA 2662 Query: 2019 L-TDGNHALDMAGLCAWVEQMAQQMRQRGIGCEDRVAIHAERSCAFVVAVLATLRVGAAY 2077 L DG H L A +A++++ G+G + VA+ AERS A V A+LA L+ G AY Sbjct: 2663 LQADGAH-WTYGQLNAAANALARRLQAAGVGPDTVVALLAERSAAMVTALLAVLKAGGAY 2721 Query: 2078 VPLDPALPAERLHYQLQDSAAVLLLSATAPDWAASVP---------VLPLASLHGVPKRV 2128 +PLDP PAERL + L+D+ V LLS ++P LP + P+ Sbjct: 2722 LPLDPDYPAERLAWMLEDARPVCLLSHRGLHRRLALPDTLLLELEDQLPGSQRGDEPQYN 2781 Query: 2129 P--YCWPAVHPGQAAYVIYTSGSTGRPKGVVVSRGALANYVAGVLERLDLREQDRSMAMV 2186 P P +H AYVIYTSGSTGRPKG S AL N + + + L+E D ++ Sbjct: 2782 PQHNPQPPLHGEHLAYVIYTSGSTGRPKGAGNSHRALYNRLRWMQQAYALQEGD-AVLQK 2840 Query: 2187 STVGADLGHTVLFGALCSGRLLHLIPPQCSFDPDAMASYMEQHQVDVLKIVPSHLQALLH 2246 + G D+ L +G L + PP DP +A+ + +H V L VPS LQA L Sbjct: 2841 TPFGFDVSVWEFLWPLMTGARLVMAPPGAHRDPAELAALIREHGVSTLHFVPSMLQAFLA 2900 Query: 2247 AASPASVLPRSRLVLGGEASRKPLLAHIASLRPQCRVMNHYGPTETTVGVLTQEASSALD 2306 + A+ +++ GEA +L PQ + N YGPTE + V Sbjct: 2901 SGQAAACTSLRQVICSGEALPAEARDQFFALLPQAALHNLYGPTEAAIDVTHWTCQHG-- 2958 Query: 2307 EADSLPIGQPIAQARAYVLDAELQPVPQGVAGELYLAGHGVARAYQQRPAQSAERFVADL 2366 + +PIGQPI+ RA VLDA+L +P GVAGELYL G G+AR Y RP +AERFVA Sbjct: 2959 DRGPVPIGQPISGLRAVVLDADLNVLPCGVAGELYLGGIGLARGYLGRPGLTAERFVASP 3018 Query: 2367 LEPGQRMYRSGDRVRQLADGSLEFLGRLDGQIKVRGYRVELREIAALLQSLEAVAQAEVV 2426 G+R+YR+GD VR DG +++LGRLD Q+K+RG R+EL EI A L +L+ V +A VV Sbjct: 3019 FGQGERLYRTGDLVRWREDGQIDYLGRLDHQVKIRGLRIELGEIEAQLLALDEVEEAVVV 3078 Query: 2427 VHSEPAQPGPDGEEVAPQIIAYLVPMGGQTLDVADLRQQLATRLPDYMMPTALVPLHVMP 2486 H A P + Y+ Q D A L+Q LA RLPDYM+P L L +P Sbjct: 3079 AHEHGA---------GPVLAGYVASRRWQRQDAATLKQALAARLPDYMVPAVLTLLPTLP 3129 Query: 2487 LTPNGKLDRQALPRPD-STATSVYEAARGPLEETLAGLWAELLGLPQVGRNDDFFALGGD 2545 L NGK+DR+ALP P + Y A +G +E+ LA +W LLGL +VGR D FF LGG Sbjct: 3130 LNANGKIDRKALPAPRLHSEDFAYAAPQGQVEQRLAQIWQALLGLERVGRFDHFFELGGH 3189 Query: 2546 SILVLKLVARARKRDVKLAPKMLFEGKTPAGVA---QLLTAG---SGAAGGVERIMPLPP 2599 S+L LVAR R ++G+ GVA +L+ A A +E PLPP Sbjct: 3190 SLLAASLVARLR-----------YQGEAGVGVALPLRLVFAYPRLHEMAACIEARPPLPP 3238 Query: 2600 AQ-----RNGLLPASYAQAR----------QWFLWQLDPGSSAYHINGALRLCGTLDEAA 2644 + R AS A R W Q P ++ AL L G +D Sbjct: 3239 SSWRLHLRRCCNLASGAPRRCCRRPSIGCGWWTACQARPMRPPTTMSAALMLEGVVDAVL 3298 Query: 2645 LEQAFSRLLERHPSLRTVLRADADGQVLQWVQPHACLAFKRIDLEPLAEGPRQARLHAEV 2704 LEQA L+ RH LRT DADG + + P + ++ DL L R +L Sbjct: 3299 LEQALRLLVARHDILRTGFGEDADGNPVATLHPFD-FSLEQHDLAALPPPQRDLQLDRLR 3357 Query: 2705 ASLCRQPFDLEAGPLLRIGLLRESGHRHVLVMVMHHIISDGWSMQLIMDEFASLYGACCQ 2764 S F L PLLR L+R + + VL++ +HHI++DGWS+ L+M+E A+ Y A + Sbjct: 3358 RSHAAARFALRQPPLLRAALVRLASQQQVLLLAIHHIVADGWSVALMMEEIAAAYSALQE 3417 Query: 2765 GREAGLPALPLQYADYAAWQRQWMQGGQRETQLRYWQDHLGQSQPSLLLPADHPRRPDGL 2824 GR P LPLQYADYAAWQ E + +W+D L + LP+ PR Sbjct: 3418 GRSYAPPPLPLQYADYAAWQVAGAGSRMLEDSIAWWRDALAGVPATPYLPSTRPRPARAT 3477 Query: 2825 YRAARHEAVLPPPLVAALRQRVQSDGGTLFAVLLAAAQLLMYRYSGQNDIRLGVPIANRH 2884 Y R LP L + ++ + +G T +AVLLA+ L+++ SG D +G +A R Sbjct: 3478 YAGQRLRMHLPAHLRSGVQALARREGVTAYAVLLASFAWLLHQRSGAGDFVVGTDVAGRS 3537 Query: 2885 LPDTEGVVGFFVNTQVLRAE---IDPRQSLARLVQLTRETAQGAQQHQDLPFEQLVEVLQ 2941 PD E +VGFFVN LR + PR S ++ + A A HQ+ F+++VE Sbjct: 3538 HPDLERLVGFFVNVLPLRLRPQTLAPRASFVAWLRHCADVAVNAFDHQEPGFDRIVEAAG 3597 Query: 2942 PQRLVGVNPLFQVMFNHQRHARPTSHQLPQLTLEPFELEEQDAQFELAIDTLEDTDG--- 2998 R NPL QV+F Q R + LP + E E E ++F+LA+ +ED G Sbjct: 3598 VPRERRWNPLVQVLFVLQNTPR-AALALPGVRAELLEPLENWSKFDLAL-FVEDHAGAGD 3655 Query: 2999 -----GLSVSLTYARELFEPQTMATMASHYLVALEALASQP 3034 G YA LF+ T+A + + LE + + P Sbjct: 3656 AADGPGWRADWVYADALFDAATVAALGRDWQRLLEQVLASP 3696 Score = 993 bits (2567), Expect = 0.0, Method: Compositional matrix adjust. Identities = 713/1742 (40%), Positives = 941/1742 (54%), Gaps = 149/1742 (8%) Query: 1995 PTIRADDVIERWAAQVSQQPGAAALTDGNHALDMAGLCAWVEQMAQQMRQRGIGCEDRVA 2054 PT+ +I A + + QP + AL G LD AGL VE +A +R G+ D VA Sbjct: 4561 PTLTVAQMI---AHRAAAQPQSPALAAGGAVLDYAGLERRVEHLAHALRSLGVAPGDIVA 4617 Query: 2055 IHAERSCAFVVAVLATLRVGAAYVPLDPALPAERLHYQLQDSAAVLLLSATAPDWAASVP 2114 + R V+A+LAT R GAAY+PLD P R LQ +A V LL A A +P Sbjct: 4618 LQLPRCAELVLALLATWRCGAAYLPLDTDSPVARRQQILQ-AAKVHLLVMEAGQSAEGLP 4676 Query: 2115 VLPLA----SLHGVPKRVPYCWPAVHPGQAAYVIYTSGSTGRPKGVVVSRGALANYVAGV 2170 A L P + P AYV++TSGSTG PKGV++ LA YV GV Sbjct: 4677 ADCTAVAWDELANSPVQASAPLPGSRMDATAYVLFTSGSTGAPKGVLIGHAQLAAYVQGV 4736 Query: 2171 LERLDLREQDRSMAMVSTVGADLGHTVLFGALCSGRLLHLIPPQCSFDPDAMASYMEQHQ 2230 + L L + R A+ TV ADLG+T LFGAL +G LH+ + D + A ++ QH Sbjct: 4737 TQALRL-DACRHWALTGTVAADLGNTALFGALANGACLHVASAEDMRDGERFAKFLRQHG 4795 Query: 2231 VDVLKIVPSHLQALLHAASPASVLPRSRLVLGGEASRKPLLAHIASLRPQCRVMNHYGPT 2290 +D LKIVPSHL ALL +PA LP + LVLGGEA+ LA I +L PQCRV NHYGPT Sbjct: 4796 IDALKIVPSHLDALLE--TPAPYLP-ATLVLGGEATAPAQLARIRALAPQCRVFNHYGPT 4852 Query: 2291 ETTVGVLTQEASSAL------DEADSLPIGQPIAQARAYVLDAELQPVPQGVAGELYLAG 2344 E TVGVL A++ D SLP+ + + A VLDA+L+P P G G+L+L G Sbjct: 4853 ECTVGVLVHRAATEAEAEAEADPGASLPLTEALPHAYVRVLDAQLRPTPAGAIGQLWLGG 4912 Query: 2345 HGVARAYQQRPAQSAERFVADLLEPGQRMYRSGDRVRQLADGSLEFLGRLDGQIKVRGYR 2404 +AR Y Q E F+ D PG+R+YRSGD L G + GR D Q+KVRG+R Sbjct: 4913 AQLARGYLD-AQQDREAFIDDPWLPGRRLYRSGDLAVLLPQGGVRLAGRADHQVKVRGFR 4971 Query: 2405 VELREIAALLQSLEAVAQAEVVVHSEPAQPGPDGEEVAPQIIAYLVPMGGQTLDVADLRQ 2464 +E EI A L++ V QA V+ PDG + A L GQ L R Sbjct: 4972 IEPGEIEAALRTQPGVRQALVLA-------APDGA-----LAACLAADHGQALPA--WRA 5017 Query: 2465 QLATRLPDYMMPTALVPLHVMPLTPNGKLDRQAL----PRPDSTATSVYEAARGPLEETL 2520 LA LP M P+ + L +P NGK+DR+AL R DS V A+G L L Sbjct: 5018 ALAEVLPAQMQPSRWLVLPELPRLGNGKVDRKALLEQLGRQDSGTPDVVAQAQGALAALL 5077 Query: 2521 AGLWAELLGLPQVGRNDDFFALGGDSILVLKLVARARKR-DVKLAPKMLFEGKT------ 2573 A A+LL P + N+DFF LG S+LV+KL+AR R+ ++ AP ++F+ Sbjct: 5078 AQQMAQLLERPAIAANEDFFELGAHSLLVIKLIARIRQSLALEAAPALVFDHPNAIALAA 5137 Query: 2574 ---------------------PAGVAQLLTAGSGAAGGVERIMPLPPAQRNGL------- 2605 A AQ + + AG R +P N + Sbjct: 5138 ALQAAAPDPDALERLAQSRLESAAPAQADSMNALTAGFPARHTRIPYRSMNDMSRPPHEH 5197 Query: 2606 LPASYAQARQWFLWQLDPGSSAYHINGALRLCGTLDEAALEQAFSRLLERHPSLRTVLRA 2665 P SY+Q + WFL Q +PG +AY++ A RL G LD AAL A L RH LRT A Sbjct: 5198 APLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRF-A 5256 Query: 2666 DADGQVLQWVQPHACLAFKRIDLEPLAEGPRQARLHAEVASLCRQPFDLEAGPLLRIGLL 2725 + DG Q P + +DL L R+ RL E+ + FDL L + L+ Sbjct: 5257 ETDGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLI 5316 Query: 2726 RESGHRHVLVMVMHHIISDGWSMQLIMDEFASLYGACCQGREAGLPALPLQYADYAAWQR 2785 HVLV+ MHHI+SD WS L++ + A Y + +A LPALP+QYADYA WQR Sbjct: 5317 ALGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQR 5376 Query: 2786 QWMQGGQRETQLRYWQDHLGQSQPSLLLPADHPRRPDGLYRAARHEAVLPPPLVAALRQR 2845 Q +QG +LRYW D+LG SL LP D PR +R A H L L ++ Sbjct: 5377 QRVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQAF 5436 Query: 2846 VQSDGGTLFAVLLAAAQLLMYRYSGQNDIRLGVPIANRHLPDTEGVVGFFVNTQVLRAEI 2905 ++ T F L+AA Q+L+ RYSGQ+D +G P A R+ + + +VGFFV TQ+ RA + Sbjct: 5437 CRAQHCTPFVALMAAWQVLLSRYSGQSDFLVGAPNAGRNHAELQDLVGFFVTTQLYRARL 5496 Query: 2906 DPRQSLARLVQLTRETAQGAQQHQDLPFEQLVEVLQPQRLVGVNPLFQVMFNHQRHARPT 2965 P ++ LV+ R A +H DLPFE L+E + +R G NPLFQVMF Q Sbjct: 5497 TPELTVRELVRQVRGDMLAALEHGDLPFEALLEHRKVERDPGRNPLFQVMFGLQMVGEGA 5556 Query: 2966 SH-QLPQLTLEPFELEEQDAQFELAIDTLEDTDGGLSVSLTYARELFEPQTMATMASHYL 3024 S + P L + A+F+L++D ++ G + L YA +LF+ T+A MA HY Sbjct: 5557 SALAFDDIVTAPLPLAQDSAKFDLSLD-VKVIKGEVHCRLEYASDLFDAATIAAMAGHYR 5615 Query: 3025 VALEALASQPQCRVGEIDWLGPAERSRLAAWGD----KVSPYATPAVITTRIAQRASIQP 3080 L A P+ V ++ L E++RL +WGD + P + A + I +A+ P Sbjct: 5616 NLLRGFAEAPERPVAQLALLDQDEQARLRSWGDPQLREALPPTSSASLAGLIEAQAAAIP 5675 Query: 3081 DAVALISGNRSMSYGQLNTRVNQLAHYLLQRGLQPEARVGVALERSADMVVAVLAILKAG 3140 DAVA++ G + MSY QLN N+LAH LLQ+G+ E R+G+A RS +M+V +LAILKAG Sbjct: 5676 DAVAVVCGPQQMSYAQLNRAANRLAHRLLQQGVGLEDRIGLAAPRSLEMIVGLLAILKAG 5735 Query: 3141 ATYVPLDPDYPVQRLAAIIEDSALSLLLSQTSVSQRLPG--GRAEQTL------------ 3186 A YVPLDPDYP RLA +++ +R PG GRA +L Sbjct: 5736 AAYVPLDPDYPADRLAYMVQ------------ACRRHPGVDGRARVSLPGPRKACAHWRS 5783 Query: 3187 ---YLDQLDLQAQPHDEPDVTIHSDSLAYVIYTSGSTGRPKGVGISHRCLME-HGQIAAD 3242 + D A P P V +H D+LAY+IYTSGSTGRPKG +SH ++ GQ AA Sbjct: 5784 PRPWAD----DAAPAHNPGVVLHPDNLAYIIYTSGSTGRPKGAQLSHANVLRLLGQTAA- 5838 Query: 3243 FFGLTPQDCMLQFSTLNFDGCIEQLFPPLLVGAAVVL------RGPELWDSQRLHVELLA 3296 +F +D F + FD + ++F L G +V+ R PE D L VE Sbjct: 5839 WFDFGREDVWTLFHSYAFDFSVWEIFGALCYGGRLVVVPFAVSRSPE--DFLALLVE--- 5893 Query: 3297 HRISVLDLTTAYWLLLVQDFARMGVPDYGV-LRRVHVGGEAMPPEGIKAW-RDAGLAQVE 3354 R++VL+ T + + L+Q A +P + LR V GGEA+ PE ++ W G + Sbjct: 5894 QRVTVLNQTPSAFRQLLQLPALRQLPSEALALRTVIFGGEALEPEMLRPWITQFGDQRPA 5953 Query: 3355 LFNTYGPTEATVTASILSCAPYVSGQTVLPAQM-----PIGAPLAGRKLRVLDAELSPLP 3409 L N YG TE TV +V+ + +L A + PIGA + L VLD +L+ P Sbjct: 5954 LINMYGITETTV---------HVTYRRLLRADLDASRSPIGAAIPDLGLYVLDQQLNLAP 6004 Query: 3410 IGVAGELCIGGELLARGYLNQPGLSAERFVADPL---GDGGARLYRTGDLVRWTHAGQLE 3466 GV GEL + G LARGYLN+ LSAERFVA+P G+ G+RLYRTGDLVRW H GQ++ Sbjct: 6005 AGVPGELYVSGAGLARGYLNRAALSAERFVANPFARAGEEGSRLYRTGDLVRWRHDGQMD 6064 Query: 3467 YLGRIDHQVKIRGFRIEMGEIESIMLAQPEVREAVVVAREGVGSLQLVAYVTPQHG---R 3523 YLGRID QVKIRGFRIE+GEIE+ +LAQP V A V+ R+ + +LV Y++PQ G Sbjct: 6065 YLGRIDQQVKIRGFRIELGEIEAQLLAQPGVGAATVMVRQDAATPRLVGYLSPQAGIAPE 6124 Query: 3524 HIETAELRECLVRHLPDYMVPAALVVLPALPLNANGKVDRKALPEPVYESRTGHEPPQGE 3583 ++T LR L LPDYMVPAALV+LPALPLN NGKVDRKALP P +RT + PQG Sbjct: 6125 ALDTGALRTALGAVLPDYMVPAALVMLPALPLNINGKVDRKALPAPELAARTAYAAPQGA 6184 Query: 3584 CEQALAAIWAEVLGLPAVGRHDNFFELGGHSLSILRIQSRIQQQFPASALPLRSHFDHPT 3643 E+ LAAIW EVL AVGR DNFFELGG S+ L+I SR ++ A+ R F+ T Sbjct: 6185 LEEQLAAIWREVLKGGAVGRDDNFFELGGDSILSLQIVSRARRA--GIAITARQMFERQT 6242 Query: 3644 IA 3645 +A Sbjct: 6243 VA 6244 Score = 757 bits (1955), Expect = 0.0, Method: Compositional matrix adjust. Identities = 566/1319 (42%), Positives = 716/1319 (54%), Gaps = 95/1319 (7%) Query: 40 ALPFATRAPGTPAPLSFAQQRLWYLWKLTPQSSAYHLAGGLRLQGPLEAAALERAVDALA 99 ALP A R PLS Q + + P SAY + + G L+AA E+A Sbjct: 6730 ALPLAARNVDDIYPLSPMQAGMLFHSVFEPGGSAYINQLRVDIDG-LDAARFEQAWQDTV 6788 Query: 100 LHHPALRTVLREDADGNVTQTVLPACAWSLSRQDLSLLPAHRRQDA-LREQVQRLCSRPF 158 H LRT Q V A LS+ D A + L QR ++ F Sbjct: 6789 AAHDILRTGFLHQP--RPLQWVARRVASPLSQLDWRDAAAGQSLGGELDALAQRQLAQGF 6846 Query: 159 ELDGGALVRACLLQVDEQEHQLIVVMHHIISDAQSTQLILAELLALY-QAARQGQAISAA 217 +L L+R L++ Q H LI +HH++ D ST ++L E+L Y QA GQA Sbjct: 6847 DLAAPPLMRLVLVRTGAQRHHLIWTVHHLLLDGWSTSMLLGEVLRRYAQATAAGQAKPTK 6906 Query: 218 WHGPDLGDYAVWQRQCLNSTQAERQLAWWKAQLGNSSPVLELPTDHARRPDGQYGAASWR 277 DY W L E +W+ QL L R + G R Sbjct: 6907 L-ALRYRDYIGW----LQGRDQEATRRFWEIQLARLQQPTRLADAMPRPSTPESGHGEHR 6961 Query: 278 IVLEPALLDALRRRAQGQGCSLFVVLLCAFQALLYRHT---SQRDVRVGVPVSHRLRSEL 334 +L+ AL L A+ Q +L ++ A+ LL R+T + V G V+ R +EL Sbjct: 6962 ELLDAALTARLNEAARAQRITLNTLVQAAWALLLQRYTYAAHDQGVVFGATVAGR-PAEL 7020 Query: 335 AAA---VGFFVDTQVLRAELAGQTTLESLLAQVRDTSFAAQAHRDIPLERLVEVLQPERS 391 +G F++T + + ++ + A+ + PL V++ Q Sbjct: 7021 TGVEQLLGLFINTLPVIVATPPHQPAGDWMRALQAQNLQAREYEHTPL---VDI-QRWSG 7076 Query: 392 IGRTPLFQ--VMFNHLREQADGSQSWP-GLSVQRLDFDAAVAQFELTLETSEEANGELSA 448 G LF ++F + A SQ P GL+ + + +T+ + A L Sbjct: 7077 QGAQALFDSILVFENYPVDATLSQGAPAGLAFSSVRHREET-NYPMTVVVN--AGDTLQL 7133 Query: 449 TFRYARELFDESSIARMAQHYVAILQALATQPQLRVAELQLRGAEEDRQLHSWGVNNEQH 508 RYAR F + R+ H +LQ LA PQ + L L +E GVN E H Sbjct: 7134 QLRYARAQFAHEMVERIGAHLRHLLQVLAEHPQQAIGSLGLLPGDELAAWRESGVNRELH 7193 Query: 509 AEVMEPVHEQIARQARRQPEATALLFGRQQLSYGALERRANQLAHRLIRLGAGPEVKVGI 568 A PVH I RQA P A ALL+ L Y +L ++AN+LAHRL+ GAGPE VG+ Sbjct: 7194 A-FDAPVHRLIERQAAATPSAAALLYEDLVLDYRSLNQQANRLAHRLLAEGAGPERIVGV 7252 Query: 569 AVERSLEMVIGLLGILKAGAAYVPLDPEYPAQRLQYMMQDSGMRLLLTQQHVLPTLPPLA 628 A R+ EMV+ LL +LKAGAAY+PLDP+ P RL MM DSG+ LLLTQ + L A Sbjct: 7253 AARRAPEMVVALLAVLKAGAAYLPLDPDLPPARLADMMADSGLSLLLTQTALRAELTAPA 7312 Query: 629 GLPVLALD---QLDLDDEAHQPPAVRVHGENLAYVIYTSGSTGQPKGVANRHCALRNRLA 685 + VL LD Q + P + V + LAYVIYTSGSTG+PKG NRH +L NRLA Sbjct: 7313 AVRVLELDAPGQPWAEGMPDHDPGIEVAPDGLAYVIYTSGSTGKPKGAGNRHVSLHNRLA 7372 Query: 686 WMQQAYRLEPHDTVLQKTPFSFDVSVWEFFWPLMIGARLALAQPGDHRDPARLVEQIQRH 745 WMQ+AY + P +TVLQKTPF FDVSVWEFFWPLM GARLALA P +HRDPA L +I+RH Sbjct: 7373 WMQEAYPIGPGNTVLQKTPFGFDVSVWEFFWPLMTGARLALAAPDEHRDPALLAARIRRH 7432 Query: 746 AVSTLHFVPSMLQAFLAHDEIEGCSSLHRLICSGEALPVEAQQGVFARLPQVALYNLYGP 805 AV TLHFVPSMLQ F+AH + C SL ++ICSGEALP E Q+ FARLPQ+AL+NLYGP Sbjct: 7433 AVDTLHFVPSMLQGFVAHPDSAQCHSLRQVICSGEALPAELQEQAFARLPQIALHNLYGP 7492 Query: 806 TEAAIDVTHWTCRADGRSQVPIGRPISSIRTLVLDGDLNLAPQGVPGELYLGGIGLARGY 865 TEAAIDVTHWTCR RS VPIGRPIS VLDG LN P G+ GELYLGGIGLARGY Sbjct: 7493 TEAAIDVTHWTCRPGERS-VPIGRPISHTAAYVLDGGLNPLPHGIAGELYLGGIGLARGY 7551 Query: 866 LGRAGLSAERFVADPFSADGERLYRTGDLVRWNREGQLDYLGRLDHQVKIRGLRIELGEI 925 LGR GLSAERFVADPF+ADG R+YRTGDLVR +G+++YLGR DHQVKIRGLRIELGEI Sbjct: 7552 LGRPGLSAERFVADPFAADGSRMYRTGDLVRRRADGEIEYLGRTDHQVKIRGLRIELGEI 7611 Query: 926 EARLLAQPGVREAVVVARESAGT-SRLVAYVS--GTDLVAATLRSALTKDLPDYMVPALI 982 EA+LLAQPGV AVVVA G +RLV Y + G L A LR+AL + LPDYMVP + Sbjct: 7612 EAQLLAQPGVAAAVVVALVEPGRPARLVGYAADPGGMLEAEALRAALLQSLPDYMVPQRL 7671 Query: 983 EVLEHLPLNANGKVDRRALPDPAQPLQRAYEAPRGQAEQVLAAVWAEVLGLQQVGRHDNF 1042 +L LPLNANGKVDR+ALP P Q YEAP+GQ E LAA+WAEVL LQ+VGRHDNF Sbjct: 7672 ILLPALPLNANGKVDRKALPRPDFNEQGGYEAPQGQTEIGLAAIWAEVLRLQRVGRHDNF 7731 Query: 1043 FELGGDSILSLQIVAGLRRRGSQLAPRLIFERQTIAQLA--------PAIAHS------- 1087 FELGGDSILSLQIVA +G L PR +F+ QT+A+LA PA + Sbjct: 7732 FELGGDSILSLQIVARAHEQGWPLTPRQLFQSQTVAELAQQCDQLQPPAPTQAVTAARGR 7791 Query: 1088 -----TAPQLHAQVSVQGEL----PLLPIQAE--FFAMDIPVRHHWNQSILLATDAPLDM 1136 +A Q AQ+++QGEL PL P+Q F M+ P + + + + LD Sbjct: 7792 LEDYLSAAQT-AQLALQGELEDVYPLSPMQQGMLFHTMESPGSGLYVNQLSVRVEG-LDE 7849 Query: 1137 AALNTALQAVVAHHDSLRLRYTRDDQGQWRQTYGQHDPAQLRELLW--VRQGLPGNAIAP 1194 A A Q+V+A H +R + W+ Y Q A R L + Q A P Sbjct: 7850 ARFAQAWQSVLARHPVMRTGFL------WQADYAQPLQAVWRTLAFGIEVQDWSARATMP 7903 Query: 1195 LCEQAQR---------SLNLARGPLLRAVAMELEEGGWRLLLVIHHLVVDGVSWRILLAD 1245 C + + PL+RA + L G +L+ +HH+++DG S L+ + Sbjct: 7904 SCRRRLPPLRRPILRAASTCCNRPLVRATLLRLGPGQHQLVWTMHHILLDGWSTSALMQE 7963 Query: 1246 LQQAYRQCVALEPLVLPARTASYQQWAHVLQGRHGALLPQ--RPYWQAQMQP---PSVL 1299 L AY +P LPA Y Q+ G L PQ + YW +Q PS+L Sbjct: 7964 LMLAY----GGQP--LPAPGPDYAQYI----GWLATLDPQAAQRYWMGALQALDGPSLL 8012 Score = 612 bits (1579), Expect = e-175, Method: Compositional matrix adjust. Identities = 509/1311 (38%), Positives = 673/1311 (51%), Gaps = 108/1311 (8%) Query: 1558 YPLSPMQSGMLFHSVSEPDNAAYTMQMQVALEA-LQPERFRAAWQAVLDRHAILRSAILQ 1616 +PL+ Q G+ +PD+AAY + + L LQ E A + RHA LR+ Sbjct: 691 FPLTQAQQGLWLTWQLQPDSAAYNLAGVLDLRGELQVEALEDALCDLAARHAALRTLFPL 750 Query: 1617 RDDAPLQWV-----ARRVVLPWQLRDCRHSPDLAAELDELA-RREREAGFDLARPPLMRL 1670 RD P+Q V AR ++L LR R D A+ A +R F L +R Sbjct: 751 RDGTPVQQVLDIDEARPMLLRSDLR--RQPADKRAQAAASALQRFHAQAFRLDSETPLRA 808 Query: 1671 MLVSTGEQGYHLIWTVHHLLLDGWSTSQLLGEVLRHY----AGQTLDEPVAAY--GDYIR 1724 MLV + L +HH+ DGWS +L E+ Y AG P GDY Sbjct: 809 MLVQLEPHHFRLGLCIHHIAADGWSLGIILDELTAAYEARCAGAAPSWPALELQPGDYAV 868 Query: 1725 WLQGRDQQASRHHWQSLLHRLQEPSLLVARLP-PAKQPNRARDYR---QYTCCLGQAQTR 1780 W + R Q S + L + A LP P +P +A + Q+ L A + Sbjct: 869 WQRQRSQPGSPEFQRQLDYWRARLEGAPALLPLPTDRPRQAGAHGGEGQHRWRLSAALST 928 Query: 1781 RLVEFARARHLTLSTLVQAAWALLLQRYAGHGTVCFGATTAGRPMDLAGAESMLGLFINT 1840 L + A ++ +TL V A + L LQR +G +C GA A R ++++ IN Sbjct: 929 ALRKLAASQGVTLYGAVLALFTLALQRLSGQSDLCVGAPLADRRRR--QTQALVAYLINV 986 Query: 1841 LPVVTTLTPQTALDEWLQQLQRQSAQSREHEYTPLYEI------QRLAGHSGQSLFDTVV 1894 V T + ++ ++Q+Q+ +++ H+ PL + +R+AG LF V Sbjct: 987 QVVRTRIDERSDFLALMRQVQQAVQEAQAHQDLPLDALMSALQPERVAG--ANPLFQ-VK 1043 Query: 1895 VFENYPVDAALHSQEVDKLVVGEVRFSSGNHYPLTLRVSLAEQLQIDFLHDTGMIAPELL 1954 + + +D V E++ ++ +H+ L+L + A++ ID L AP L Sbjct: 1044 CTQQQAIATVRRMGGLDMRV--ELQANAESHFDLSLDFTDADE-GIDILL---AYAPALF 1097 Query: 1955 -ARMAAQFTSLLEQFSQDDGETRRRRLADLSLTDLPAPLQGPTIRADDVIERWAAQVSQQ 2013 A A F LL+ +Q LADL + A+DV W Q Q Sbjct: 1098 DAETVAGFAGLLQALAQQVVAAPALALADLQAFPPVSAADQVLQPAEDVAACWRRQALAQ 1157 Query: 2014 PGAAALTDGNHALDMAGLCAWVEQMAQQMRQRGIGCEDRVAIHAERSCAFVVAVLATLRV 2073 P A AL G + + C + G G E RVA++A R FV +LA L Sbjct: 1158 PDAVALRCGAQFISTSSCCNGSMRWRSAWHAAGAGPESRVALYAGRDIDFVCGMLAVLDT 1217 Query: 2074 GAAYVPLDPALPAERLHYQLQDSAA--VLLLSATAPDW--AASVPVLPLASLHGVPKRVP 2129 GAAYVPLDP LPAERL +QLQDS A VL +AP W A VP+L L + P P Sbjct: 1218 GAAYVPLDPQLPAERLAWQLQDSGARWVLHEGQSAPAWLAQAGVPLLSLEAAGTAPAS-P 1276 Query: 2130 YCWPAVHPGQAAYVIYTSGSTGRPKGVVVSRGALANYVAGVLERLDLREQDRSMAMVSTV 2189 + VHP QAAY+IYTSGSTGRPKGV+V+RG LANYVA VLE+L L RSMAM+STV Sbjct: 1277 WTPFPVHPAQAAYLIYTSGSTGRPKGVLVTRGGLANYVAAVLEKLALPAAARSMAMISTV 1336 Query: 2190 GADLGHTVLFGALCSGRLLHLIPPQCSFDPDAMASYMEQHQVDVLKIVPSHLQALLHAAS 2249 ADLGHT L+GALCSGR LHLI +FDPD A+Y+ +H VDVLKIVPSHLQALLHAA Sbjct: 1337 AADLGHTTLYGALCSGRQLHLITHDLAFDPDGFAAYLHEHAVDVLKIVPSHLQALLHAAR 1396 Query: 2250 PASVLPRSRLVLGGEASRKPLLAHIASLRPQCRVMNHYGPTETTVGVLTQEASSALDEAD 2309 P VLPR LVLGGEA+ PLL IA+L+P CRV+NHYGP+ETTVGVL QEA+SA A Sbjct: 1397 PEQVLPRHTLVLGGEATGWPLLERIAALQPACRVLNHYGPSETTVGVLVQEAASASRRAA 1456 Query: 2310 SLPIGQPIAQARAYVLDAELQPVPQGVAGELYLAGHGVARAYQQRPAQSAERFVADLLEP 2369 LP+G + +A+VLD +L+ P G GELYL G G+AR Y R A +AERFVA Sbjct: 1457 VLPVGSALVGVQAWVLDRQLRRAPVGAVGELYLGGAGLARGYHGRAALTAERFVAHPFAS 1516 Query: 2370 GQRMYRSGDRVRQLADGSLEFLGRLDGQIKVRGYRVELREIAALLQSLEAVAQAEVVVHS 2429 GQR+YRSGDR R L DGS+EFLGR+D Q+K+RG+RVE E+ L L V A V+ Sbjct: 1517 GQRLYRSGDRARYLGDGSIEFLGRIDDQVKIRGHRVEPGEVRQQLLRLAGVVDAAVL--- 1573 Query: 2430 EPAQPGPDGEEVAPQIIAYLVPMGGQTLDVADLRQQLATRLPDYMMPTALVPLHVMPLTP 2489 A P D + Q+ ++V G D A R LA LPDY++PT L P+ +PLT Sbjct: 1574 --ALPAADDAQRL-QLHGFIVCAAGAVADPAGWRATLAADLPDYLLPT-LTPVPALPLTA 1629 Query: 2490 NGKLDRQALPRPDSTATSVYE-------------AARGPLEETLAGLWAELLGLPQVGRN 2536 NGKLDRQAL + A + + A +G LE LA +WAE+L LPQVGR Sbjct: 1630 NGKLDRQALAGLMAGAMAAPQQQVPQVQQAHQAGAPQGELEHKLAAIWAEVLKLPQVGRE 1689 Query: 2537 DDFFALGGDSILVLKLVARARKRDVKLAPKMLFEGKTPAGVAQ-------LLTAGSGAAG 2589 D+FF LGGDSIL LK+VARARK +++APK + E +T A + L + A Sbjct: 1690 DNFFELGGDSILTLKIVARARKEGLRIAPKAMMEKQTVAAIVAAGAVQGLLAATPAPAVV 1749 Query: 2590 GVERIMPLPPAQRNGLLPASYAQARQWFLWQLDPGSSAYHINGALRLCG-TLDEAALEQA 2648 +PL P Q WF Q ++ H N ++ L LD L +A Sbjct: 1750 AAPADIPLTPVQ-------------HWFFEQ--GFATPQHWNQSVLLNAPGLDADVLRRA 1794 Query: 2649 FSRLLERHPSLRTVLRADADGQVLQWVQPH--ACLAFKRID-LEPLAEGPRQARLHAEVA 2705 + L +RH SLR LR +G QW Q A L + ID EP A A Sbjct: 1795 LALLAQRHESLR--LRFVQEGG--QWRQRRGPALLPLEIIDGDEPGA--------IAAAG 1842 Query: 2706 SLCRQPFDLEAGPLLRIGLLR--ESGHRHVLVMVMHHIISDGWSMQLIMDEFASLYGACC 2763 L ++ DL GPL+ +R G + L++ HH++ DG S ++++D+ A LY Sbjct: 1843 ELVQRSLDLAQGPLMAAAWIRLDAQGKQGRLLLAGHHLVVDGVSWRVLLDDLAGLYHTLQ 1902 Query: 2764 QGREAGLPALPLQYADYAAWQRQWMQGGQR---ETQLRYWQDHLGQSQPSL 2811 QG G PA D W + QR QL YW+ + +P L Sbjct: 1903 QG---GTPAELPPATDLYTWSQALRAHAQRPAVTDQLAYWRSVVDTPEPPL 1950 Score = 534 bits (1376), Expect = e-152, Method: Compositional matrix adjust. Identities = 417/1089 (38%), Positives = 563/1089 (51%), Gaps = 66/1089 (6%) Query: 2597 LPPAQRN--GLLPASYAQARQWFLWQLDPGSSAYHINGALRLCGTLDEAALEQAFSRLLE 2654 LP A RN + P S QA F +PG SAY IN LD A EQA+ + Sbjct: 6731 LPLAARNVDDIYPLSPMQAGMLFHSVFEPGGSAY-INQLRVDIDGLDAARFEQAWQDTVA 6789 Query: 2655 RHPSLRTVLRADADGQVLQWVQPHACLAFKRIDLEPLAEGPRQARLHAEVASLCR----Q 2710 H LRT + LQWV ++D A G L E+ +L + Q Sbjct: 6790 AHDILRTGFLHQP--RPLQWVARRVASPLSQLDWRDAAAG---QSLGGELDALAQRQLAQ 6844 Query: 2711 PFDLEAGPLLRIGLLRESGHRHVLVMVMHHIISDGWSMQLIMDEFASLYGACCQGREAGL 2770 FDL A PL+R+ L+R RH L+ +HH++ DGWS +++ E Y +A Sbjct: 6845 GFDLAAPPLMRLVLVRTGAQRHHLIWTVHHLLLDGWSTSMLLGEVLRRYAQATAAGQAKP 6904 Query: 2771 PALPLQYADYAAWQRQWMQGGQRETQLRYWQDHLGQSQPSLLLPADHPRRPDGLYRAARH 2830 L L+Y DY W +QG +E R+W+ L + Q L PR H Sbjct: 6905 TKLALRYRDYIGW----LQGRDQEATRRFWEIQLARLQQPTRLADAMPRPSTPESGHGEH 6960 Query: 2831 EAVLPPPLVAALRQRVQSDGGTLFAVLLAAAQLLMYRYS---GQNDIRLGVPIANR--HL 2885 +L L A L + ++ TL ++ AA LL+ RY+ + G +A R L Sbjct: 6961 RELLDAALTARLNEAARAQRITLNTLVQAAWALLLQRYTYAAHDQGVVFGATVAGRPAEL 7020 Query: 2886 PDTEGVVGFFVNTQVLRAEIDPRQSLARLVQLTRETAQGAQQHQDLPFEQLVEVLQPQRL 2945 E ++G F+NT + P Q ++ + A++++ P LV++ Q Sbjct: 7021 TGVEQLLGLFINTLPVIVATPPHQPAGDWMRALQAQNLQAREYEHTP---LVDI-QRWSG 7076 Query: 2946 VGVNPLFQVMFNHQRHARPTSHQLPQ-----LTLEPFELEEQDAQFELAIDTLEDTDGGL 3000 G LF + + + P L Q L E+ + DT L Sbjct: 7077 QGAQALFDSILVFENY--PVDATLSQGAPAGLAFSSVRHREETNYPMTVVVNAGDT---L 7131 Query: 3001 SVSLTYARELFEPQTMATMASHYLVALEALASQPQCRVGEIDWLGPAERSRLAAW---GD 3057 + L YAR F + + + +H L+ LA PQ +G + L E LAAW G Sbjct: 7132 QLQLRYARAQFAHEMVERIGAHLRHLLQVLAEHPQQAIGSLGLLPGDE---LAAWRESGV 7188 Query: 3058 KVSPYATPAVITTRIAQRASIQPDAVALISGNRSMSYGQLNTRVNQLAHYLLQRGLQPEA 3117 +A A + I ++A+ P A AL+ + + Y LN + N+LAH LL G PE Sbjct: 7189 NRELHAFDAPVHRLIERQAAATPSAAALLYEDLVLDYRSLNQQANRLAHRLLAEGAGPER 7248 Query: 3118 RVGVALERSADMVVAVLAILKAGATYVPLDPDYPVQRLAAIIEDSALSLLLSQTSVSQRL 3177 VGVA R+ +MVVA+LA+LKAGA Y+PLDPD P RLA ++ DS LSLLL+QT++ L Sbjct: 7249 IVGVAARRAPEMVVALLAVLKAGAAYLPLDPDLPPARLADMMADSGLSLLLTQTALRAEL 7308 Query: 3178 PGGRAEQTLYLD---QLDLQAQPHDEPDVTIHSDSLAYVIYTSGSTGRPKGVGISHRCLM 3234 A + L LD Q + P +P + + D LAYVIYTSGSTG+PKG G H L Sbjct: 7309 TAPAAVRVLELDAPGQPWAEGMPDHDPGIEVAPDGLAYVIYTSGSTGKPKGAGNRHVSLH 7368 Query: 3235 EHGQIAADFFGLTPQDCMLQFSTLNFDGCIEQLFPPLLVGAAVVLRGPELWDSQRLHVEL 3294 + + + P + +LQ + FD + + F PL+ GA + L P D R L Sbjct: 7369 NRLAWMQEAYPIGPGNTVLQKTPFGFDVSVWEFFWPLMTGARLALAAP---DEHR-DPAL 7424 Query: 3295 LAHRISVLDLTTAYWL-LLVQDFARMGVPDYG---VLRRVHVGGEAMPPEGIKAWRDAGL 3350 LA RI + T +++ ++Q F + PD LR+V GEA+P E ++ A L Sbjct: 7425 LAARIRRHAVDTLHFVPSMLQGF--VAHPDSAQCHSLRQVICSGEALPAE-LQEQAFARL 7481 Query: 3351 AQVELFNTYGPTEATVTASILSCAPYVSGQTVLPAQMPIGAPLAGRKLRVLDAELSPLPI 3410 Q+ L N YGPTEA + + +C P G+ +PIG P++ VLD L+PLP Sbjct: 7482 PQIALHNLYGPTEAAIDVTHWTCRP---GER----SVPIGRPISHTAAYVLDGGLNPLPH 7534 Query: 3411 GVAGELCIGGELLARGYLNQPGLSAERFVADPLGDGGARLYRTGDLVRWTHAGQLEYLGR 3470 G+AGEL +GG LARGYL +PGLSAERFVADP G+R+YRTGDLVR G++EYLGR Sbjct: 7535 GIAGELYLGGIGLARGYLGRPGLSAERFVADPFAADGSRMYRTGDLVRRRADGEIEYLGR 7594 Query: 3471 IDHQVKIRGFRIEMGEIESIMLAQPEVREAVVVAREGVGS-LQLVAYVTPQHGRHIETAE 3529 DHQVKIRG RIE+GEIE+ +LAQP V AVVVA G +LV Y G +E Sbjct: 7595 TDHQVKIRGLRIELGEIEAQLLAQPGVAAAVVVALVEPGRPARLVGYAA-DPGGMLEAEA 7653 Query: 3530 LRECLVRHLPDYMVPAALVVLPALPLNANGKVDRKALPEPVYESRTGHEPPQGECEQALA 3589 LR L++ LPDYMVP L++LPALPLNANGKVDRKALP P + + G+E PQG+ E LA Sbjct: 7654 LRAALLQSLPDYMVPQRLILLPALPLNANGKVDRKALPRPDFNEQGGYEAPQGQTEIGLA 7713 Query: 3590 AIWAEVLGLPAVGRHDNFFELGGHSLSILRIQSRIQQQFPASALPLRSHFDHPTIAAFAQ 3649 AIWAEVL L VGRHDNFFELGG S+ L+I +R +Q L R F T+A AQ Sbjct: 7714 AIWAEVLRLQRVGRHDNFFELGGDSILSLQIVARAHEQ--GWPLTPRQLFQSQTVAELAQ 7771 Query: 3650 QLTRSSLPS 3658 Q + P+ Sbjct: 7772 QCDQLQPPA 7780 Score = 506 bits (1303), Expect = e-143, Method: Compositional matrix adjust. Identities = 468/1354 (34%), Positives = 641/1354 (47%), Gaps = 104/1354 (7%) Query: 2335 GVAGELYLAGHGVARAYQQRPAQSAERFVADLLEPGQRMYRSGDRVRQLADGSLEFLGRL 2394 G GE+ + G V + Y QRP +SA FV G+R R+GD + L DG L GR Sbjct: 402 GAVGEIEVCGPSVTQGYWQRPQESAAAFVE---RDGRRWLRTGD-LGFLRDGQLYIAGRR 457 Query: 2395 DGQIKVRGYRVELREIA-ALLQSLEAVAQAEVVVHSEPAQPGPDGEEVAPQI---IAYLV 2450 I VRG V ++I A+ +EAV + V + G +G VA +I + L Sbjct: 458 KDLIIVRGQNVYPQDIERAVEDQVEAVRKGRVAAFAVNTGDG-EGIGVAAEISRGMQKLA 516 Query: 2451 PMGGQTLDVADLRQQLATRLPDYMMPTALVPLHVMPLTPNGKLDRQAL------------ 2498 G +A+ Q + P ++ L+ +P T +GKL R A Sbjct: 517 APGAIASAIAEAVAQASLEAPQVVI---LLNPGGLPKTSSGKLQRSACRSGWRNGELDAW 573 Query: 2499 -----------PRPDSTATSVYEAARGPLEETLAGLWAELLGLPQVGRNDDFFALGGDSI 2547 P + E +G +E LA +W L GR DFF GG S+ Sbjct: 574 AIVEEGELKAGPSDAQGGELLAEPPQGDIETALAAIWQSALKRAIAGRQADFFRSGGSSL 633 Query: 2548 LVLKLVARARKR-DVKLAPKMLFEGKTPAGVAQLLTAGSGAAGGVERIMPLPPA-QRNGL 2605 +++VA R V+ P MLF T A A + A A + PLP Sbjct: 634 AAMQVVAAVVDRWQVEFTPAMLFAAPTLAASAAQIAALLEAGA---QAAPLPACVDGQSE 690 Query: 2606 LPASYAQARQWFLWQLDPGSSAYHINGALRLCGTLDEAALEQAFSRLLERHPSLRTVLRA 2665 P + AQ W WQL P S+AY++ G L L G L ALE A L RH +LRT+ Sbjct: 691 FPLTQAQQGLWLTWQLQPDSAAYNLAGVLDLRGELQVEALEDALCDLAARHAALRTLFPL 750 Query: 2666 DADGQVLQWVQP--HACLAFKRIDLEPLAEGPRQARLHAEVASLCR---QPFDLEAGPLL 2720 DG +Q V A R DL P R A ++L R Q F L++ L Sbjct: 751 R-DGTPVQQVLDIDEARPMLLRSDLR---RQPADKRAQAAASALQRFHAQAFRLDSETPL 806 Query: 2721 RIGLLRESGHRHVLVMVMHHIISDGWSMQLIMDEFASLYGACCQGREAGLPALPLQYADY 2780 R L++ H L + +HHI +DGWS+ +I+DE + Y A C G PAL LQ DY Sbjct: 807 RAMLVQLEPHHFRLGLCIHHIAADGWSLGIILDELTAAYEARCAGAAPSWPALELQPGDY 866 Query: 2781 AAWQRQWMQGGQRE--TQLRYWQDHLGQSQPSLL-LPADHPRRPDGLYRAARHEAVLPPP 2837 A WQRQ Q G E QL YW+ L + P+LL LP D PR+ +H L Sbjct: 867 AVWQRQRSQPGSPEFQRQLDYWRARL-EGAPALLPLPTDRPRQAGAHGGEGQHRWRLSAA 925 Query: 2838 LVAALRQRVQSDGGTLFAVLLAAAQLLMYRYSGQNDIRLGVPIANRHLPDTEGVVGFFVN 2897 L ALR+ S G TL+ +LA L + R SGQ+D+ +G P+A+R T+ +V + +N Sbjct: 926 LSTALRKLAASQGVTLYGAVLALFTLALQRLSGQSDLCVGAPLADRRRRQTQALVAYLIN 985 Query: 2898 TQVLRAEIDPRQSLARLVQLTRETAQGAQQHQDLPFEQLVEVLQPQRLVGVNPLFQVMFN 2957 QV+R ID R L++ ++ Q AQ HQDLP + L+ LQP+R+ G NPLFQV Sbjct: 986 VQVVRTRIDERSDFLALMRQVQQAVQEAQAHQDLPLDALMSALQPERVAGANPLFQVKCT 1045 Query: 2958 HQRHARPTSHQLPQLTLEPFELEEQDAQFELAIDTLEDTDGGLSVSLTYARELFEPQTMA 3017 Q+ A T ++ L + ++ F+L++D D D G+ + L YA LF+ +T+A Sbjct: 1046 -QQQAIATVRRMGGLDMRVELQANAESHFDLSLD-FTDADEGIDILLAYAPALFDAETVA 1103 Query: 3018 TMASHYLVALEALASQPQCRVGEIDWLGPAERSRLAAWGDKVSPYATPAVITTRIAQRAS 3077 A L+ALA Q A AA D+V A R ++A Sbjct: 1104 GFAG----LLQALAQQVVAAPALALADLQAFPPVSAA--DQVLQPAEDVAACWR--RQAL 1155 Query: 3078 IQPDAVALISGNRSMSYGQLNTRVNQLAHYLLQRGLQPEARVGVALERSADMVVAVLAIL 3137 QPDAVAL G + +S + G PE+RV + R D V +LA+L Sbjct: 1156 AQPDAVALRCGAQFISTSSCCNGSMRWRSAWHAAGAGPESRVALYAGRDIDFVCGMLAVL 1215 Query: 3138 KAGATYVPLDPDYPVQRLAAIIEDSALSLLLSQTSVSQRLPGGRAEQTLYLDQLDLQAQP 3197 GA YVPLDP P +RLA ++DS +L + Q P A+ + L L+ Sbjct: 1216 DTGAAYVPLDPQLPAERLAWQLQDSGARWVLHE---GQSAPAWLAQAGVPLLSLEAAGTA 1272 Query: 3198 HDEP--DVTIHSDSLAYVIYTSGSTGRPKGVGISHRCLMEHGQIAADFFGL-TPQDCMLQ 3254 P +H AY+IYTSGSTGRPKGV ++ L + + L M Sbjct: 1273 PASPWTPFPVHPAQAAYLIYTSGSTGRPKGVLVTRGGLANYVAAVLEKLALPAAARSMAM 1332 Query: 3255 FSTLNFDGCIEQLFPPLLVGAAVVLRGPEL-WDSQRLHVELLAHRISVLDLTTAYWLLLV 3313 ST+ D L+ L G + L +L +D L H + VL + ++ + Sbjct: 1333 ISTVAADLGHTTLYGALCSGRQLHLITHDLAFDPDGFAAYLHEHAVDVLKIVPSH----L 1388 Query: 3314 QDFARMGVPDYGVLRRVHV-GGEAMP---PEGIKAWRDAGLAQVELFNTYGPTEATVTAS 3369 Q P+ + R V GGEA E I A + A + N YGP+E TV Sbjct: 1389 QALLHAARPEQVLPRHTLVLGGEATGWPLLERIAALQPA----CRVLNHYGPSETTVGVL 1444 Query: 3370 ILSCAPYVSGQTVLPAQMPIGAPLAGRKLRVLDAELSPLPIGVAGELCIGGELLARGYLN 3429 + A VL P+G+ L G + VLD +L P+G GEL +GG LARGY Sbjct: 1445 VQEAASASRRAAVL----PVGSALVGVQAWVLDRQLRRAPVGAVGELYLGGAGLARGYHG 1500 Query: 3430 QPGLSAERFVADPLGDGGARLYRTGDLVRWTHAGQLEYLGRIDHQVKIRGFRIEMGEIES 3489 + L+AERFVA P G RLYR+GD R+ G +E+LGRID QVKIRG R+E GE+ Sbjct: 1501 RAALTAERFVAHPFAS-GQRLYRSGDRARYLGDGSIEFLGRIDDQVKIRGHRVEPGEVRQ 1559 Query: 3490 IMLAQPEVREAVVV---AREGVGSLQLVAYVTPQHGRHIETAELRECLVRHLPDYMVPAA 3546 +L V +A V+ A + LQL ++ G + A R L LPDY++P Sbjct: 1560 QLLRLAGVVDAAVLALPAADDAQRLQLHGFIVCAAGAVADPAGWRATLAADLPDYLLP-T 1618 Query: 3547 LVVLPALPLNANGKVDRK-----------ALPEPVYESRTGHE--PPQGECEQALAAIWA 3593 L +PALPL ANGK+DR+ A + V + + H+ PQGE E LAAIWA Sbjct: 1619 LTPVPALPLTANGKLDRQALAGLMAGAMAAPQQQVPQVQQAHQAGAPQGELEHKLAAIWA 1678 Query: 3594 EVLGLPAVGRHDNFFELGGHSLSILRIQSRIQQQ 3627 EVL LP VGR DNFFELGG S+ L+I +R +++ Sbjct: 1679 EVLKLPQVGREDNFFELGGDSILTLKIVARARKE 1712 Score = 475 bits (1223), Expect = e-134, Method: Compositional matrix adjust. Identities = 400/1088 (36%), Positives = 536/1088 (49%), Gaps = 94/1088 (8%) Query: 2608 ASYA----QARQWFLWQLDPGSSAYHINGALRLCGTLDEAALEQAFSRLLERHPSLRTVL 2663 A+YA QA +F ++ G AY L L G +DEA LE + + RHP LRT Sbjct: 2187 AAYALSPMQAGMFFHSSMNAGDGAYINQLRLDLAG-VDEARLEAVWREAVRRHPILRTGF 2245 Query: 2664 RADADGQVLQWV-QPHACLAFKRIDLEPLAEGPRQARLHAE------------VASLCRQ 2710 R D QWV QP L ++ +DL + + E A L R Sbjct: 2246 RQQGDAPE-QWVAQP--VLHWRVLDLSGQPPQQQAQQAQLEQLEQLEQLEQIAAAELARG 2302 Query: 2711 PFDLEAGPLLRIGLLRESGHRHVLVMVMHHIISDGWSMQLIMDEFASLYGACCQGREAGL 2770 FDL L+R+ L + RH L+ HH++ DGWS + E Y G E Sbjct: 2303 -FDLAQPGLMRLVLAKMGEGRHHLIWTRHHLLLDGWSSAQLFAEIVRAYA----GEEIAA 2357 Query: 2771 PALPLQYADYAAWQRQWMQGGQRETQLRYWQDHLGQSQPSLLLPADHPRRPDGLYRAARH 2830 P L Y Y W+Q +W+ L + LL PR + A H Sbjct: 2358 PTL--AYRHYI----DWLQARDGAAARDFWRAQLQHLEEPTLLAGALPRPREDASGHAEH 2411 Query: 2831 EAVLPPPLVAALRQRVQSDGGTLFAVLLAAAQLLMYRYSGQNDIRLGVPIANR--HLPDT 2888 A + P AL Q ++ T +L A L++ R GQ+ + GV + +R L Sbjct: 2412 LAAISPAQWQALCQAAKAMRITPGTLLQGAWALVLQRCCGQSAVAFGVTVVDRPAELEGI 2471 Query: 2889 EGVVGFFVNTQVLRAEIDPRQSLARLVQLTRETAQGAQQHQDLPFEQLVE--VLQPQRLV 2946 E +G F+NT L + Q + ++ A HQ+L + + + QR Sbjct: 2472 ESTLGLFINTLPLAVRLHAAQDCSDWLR--------ALLHQNLAMREFAHAPLYEIQRWS 2523 Query: 2947 GV--NPLFQVMFNHQRHARPTSHQLPQ-----LTLEPFELEEQDAQFELAIDTLEDTDGG 2999 G LF + + + P + + L L L EQ + + T++D G Sbjct: 2524 GRAGQALFDSILVLENY--PMDEAIGRAADYGLHLSGLRLHEQTSYPLTVVATVQD---G 2578 Query: 3000 LSVSLTYARELFEPQTMATMASHYLVALEALASQPQCRVGEIDWLGPAERSRLAAWGDKV 3059 LS+ L Y R F +A +A AL L + R+G+ +R + W Sbjct: 2579 LSLRLGYDRSRFGAYQVAQLADWLAQALVTLTTG-GARLGDCALGSATQRQQALGWSLNG 2637 Query: 3060 SPYATPAVITTRIAQRASIQPDAVALISGNRSMSYGQLNTRVNQLAHYLLQRGLQPEARV 3119 + + Q+AS +PDA+AL + +YGQLN N LA L G+ P+ V Sbjct: 2638 QRFDGQEPVHRLFEQQASRRPDAIALQADGAHWTYGQLNAAANALARRLQAAGVGPDTVV 2697 Query: 3120 GVALERSADMVVAVLAILKAGATYVPLDPDYPVQRLAAIIEDSALSLLLSQTSVSQRLPG 3179 + ERSA MV A+LA+LKAG Y+PLDPDYP +RLA ++ED+ LLS + +RL Sbjct: 2698 ALLAERSAAMVTALLAVLKAGGAYLPLDPDYPAERLAWMLEDARPVCLLSHRGLHRRLA- 2756 Query: 3180 GRAEQTLYL---DQL-------DLQAQPHDEPDVTIHSDSLAYVIYTSGSTGRPKGVGIS 3229 TL L DQL + Q P P +H + LAYVIYTSGSTGRPKG G S Sbjct: 2757 --LPDTLLLELEDQLPGSQRGDEPQYNPQHNPQPPLHGEHLAYVIYTSGSTGRPKGAGNS 2814 Query: 3230 HRCLMEHGQIAADFFGLTPQDCMLQFSTLNFDGCIEQLFPPLLVGAAVVLRGPELW-DSQ 3288 HR L + + L D +LQ + FD + + PL+ GA +V+ P D Sbjct: 2815 HRALYNRLRWMQQAYALQEGDAVLQKTPFGFDVSVWEFLWPLMTGARLVMAPPGAHRDPA 2874 Query: 3289 RLHVELLAHRISVLDLTTAYWLLLVQDFARMG-VPDYGVLRRVHVGGEAMPPEGIKAWRD 3347 L + H +S L + ++Q F G LR+V GEA+P E RD Sbjct: 2875 ELAALIREHGVSTLHFVPS----MLQAFLASGQAAACTSLRQVICSGEALPAEA----RD 2926 Query: 3348 ---AGLAQVELFNTYGPTEATVTASILSCAPYVSGQTVLPAQMPIGAPLAGRKLRVLDAE 3404 A L Q L N YGPTEA + + +C G +PIG P++G + VLDA+ Sbjct: 2927 QFFALLPQAALHNLYGPTEAAIDVTHWTCQHGDRGP------VPIGQPISGLRAVVLDAD 2980 Query: 3405 LSPLPIGVAGELCIGGELLARGYLNQPGLSAERFVADPLGDGGARLYRTGDLVRWTHAGQ 3464 L+ LP GVAGEL +GG LARGYL +PGL+AERFVA P G G RLYRTGDLVRW GQ Sbjct: 2981 LNVLPCGVAGELYLGGIGLARGYLGRPGLTAERFVASPFGQG-ERLYRTGDLVRWREDGQ 3039 Query: 3465 LEYLGRIDHQVKIRGFRIEMGEIESIMLAQPEVREAVVVAREGVGSLQLVAYVTPQHGRH 3524 ++YLGR+DHQVKIRG RIE+GEIE+ +LA EV EAVVVA E L YV + + Sbjct: 3040 IDYLGRLDHQVKIRGLRIELGEIEAQLLALDEVEEAVVVAHEHGAGPVLAGYVASRRWQR 3099 Query: 3525 IETAELRECLVRHLPDYMVPAALVVLPALPLNANGKVDRKALPEP-VYESRTGHEPPQGE 3583 + A L++ L LPDYMVPA L +LP LPLNANGK+DRKALP P ++ + PQG+ Sbjct: 3100 QDAATLKQALAARLPDYMVPAVLTLLPTLPLNANGKIDRKALPAPRLHSEDFAYAAPQGQ 3159 Query: 3584 CEQALAAIWAEVLGLPAVGRHDNFFELGGHSLSILRIQSRIQQQFPAS---ALPLRSHFD 3640 EQ LA IW +LGL VGR D+FFELGGHSL + +R++ Q A ALPLR F Sbjct: 3160 VEQRLAQIWQALLGLERVGRFDHFFELGGHSLLAASLVARLRYQGEAGVGVALPLRLVFA 3219 Query: 3641 HPTIAAFA 3648 +P + A Sbjct: 3220 YPRLHEMA 3227 Score = 246 bits (629), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 348/1155 (30%), Positives = 492/1155 (42%), Gaps = 128/1155 (11%) Query: 2544 GDSILVLKLVA-RARK-----RDVKLAPKMLFEGK---TPA-GVAQL----------LTA 2583 GD +++ ++A AR R + +A +FE K TPA GV+ + +T Sbjct: 4050 GDVVMLDNMIAAHARDPYEGPRKIVVAMGAMFERKDLLTPAYGVSSIEEGVASHVSSITL 4109 Query: 2584 GSGAAGGVERIMPLPPAQRNGLLPAS-----YAQARQWFLWQLDPGSSAYHINGALRLCG 2638 G R++P P +P+ A++ L Q P A H+ LRL Sbjct: 4110 TEGRGEPAPRLLPENPMHPQEQIPSDDVGFPLTAAQRSLLQQAAP---ALHLR--LRLPA 4164 Query: 2639 TLDEAALEQAFSRLLERHPSLRTVLRADADGQVLQWVQPHACLAFKRIDLEPLAEGPRQA 2698 LD A L RL RH LR LR QV + + I LE +A A Sbjct: 4165 ALDAARLTLLLERLARRHQILRCQLR-----QVPGYRELRLVDGPPTIRLEGIAHEDENA 4219 Query: 2699 RLHAEVASLCRQPFDLEAGPLLRIGLLRESGHRH--VLVMVMHHIISDGWSMQLIMDEFA 2756 +A+ Q F L R LL +GH L + +++D S+ A Sbjct: 4220 -----IAAWRAQAFGQPQTALWRAALLEHAGHGQGRELWLACSPLVADYRSL-------A 4267 Query: 2757 SLYGACCQGREAGLPALPLQYADYAAWQRQWMQGGQRE----TQLRYWQDHLGQSQPSLL 2812 +L G Q E + LQ+ ++ W + G L YWQ Q+QP+ Sbjct: 4268 TLAGELMQP-EHIVAEEVLQFGAFSDWLDDLVSGADNRDAAAAGLAYWQ---AQAQPAGE 4323 Query: 2813 LPADHPRRPDGLYRAARH----EAVLPPPLVAALRQRVQSDGGTLFAVLLAAAQLLMYRY 2868 R +GL AA E L PL AL + L AV LA L+ R Sbjct: 4324 AAPWPASRRNGLATAAPRIELFECALDAPLAQALPSSPAAAAERLHAVWLA----LLARL 4379 Query: 2869 S---GQNDIR------LGVPIANRHLPDT-EGVVGFFVNTQVLRAEIDPRQSLARLVQLT 2918 S G++ R L + HL D EG VG F LR + P+ L + Sbjct: 4380 SQAFGEDGPRTLASGWLHDCRTDEHLQDMLEGAVGRFERVLPLRLNLGPQAGLRQWQAQL 4439 Query: 2919 RETAQGAQQHQD-LPFEQLVEVLQPQRLVGVNPLFQVMFNHQRHARPTSHQLPQLTLEPF 2977 + Q ++ Q+ LP + +L R P Sbjct: 4440 AQALQQHREQQEYLPEGAALPLLFGWRDEAAQPAGWATL--------------------- 4478 Query: 2978 ELEEQDAQFELAIDTLEDTDGGLSVSLTYARELFEPQTMATMASHYLVALEALASQPQCR 3037 EL EL + L +G ++ + + + Q +A +A Y L + P+ Sbjct: 4479 ELPGPPPGAELTLLALRRPEG-WRLAWHFDTQHYGRQEIAVLAGQYRQLLARALAVPEQP 4537 Query: 3038 VGEIDWLGPAERSRLAAWGDKVSPYATPAVITTRIAQRASIQPDAVALISGNRSMSYGQL 3097 + + G A + + P T + IA RA+ QP + AL +G + Y L Sbjct: 4538 LLTLPLHGEALAAATLGQTESCLPTLT---VAQMIAHRAAAQPQSPALAAGGAVLDYAGL 4594 Query: 3098 NTRVNQLAHYLLQRGLQPEARVGVALERSADMVVAVLAILKAGATYVPLDPDYPVQRLAA 3157 RV LAH L G+ P V + L R A++V+A+LA + GA Y+PLD D PV R Sbjct: 4595 ERRVEHLAHALRSLGVAPGDIVALQLPRCAELVLALLATWRCGAAYLPLDTDSPVARRQQ 4654 Query: 3158 IIEDSALSLLLSQTSVSQRLPGGRAEQT-LYLDQLDLQAQPHDEPDVTIHSDSLAYVIYT 3216 I++ + + LL+ + Q G A+ T + D+L P D+ AYV++T Sbjct: 4655 ILQAAKVHLLVMEA--GQSAEGLPADCTAVAWDELANSPVQASAPLPGSRMDATAYVLFT 4712 Query: 3217 SGSTGRPKGVGISHRCLMEHGQIAADFFGLTPQDCMLQFSTLNFDGCIEQLFPPLLVGAA 3276 SGSTG PKGV I H L + Q L T+ D LF L GA Sbjct: 4713 SGSTGAPKGVLIGHAQLAAYVQGVTQALRLDACRHWALTGTVAADLGNTALFGALANGAC 4772 Query: 3277 V-VLRGPELWDSQRLHVELLAHRISVLDLTTAYWLLLVQDFARMGVPDYGVLRRVHVGGE 3335 + V ++ D +R L H I L + ++ L++ A +P VL GGE Sbjct: 4773 LHVASAEDMRDGERFAKFLRQHGIDALKIVPSHLDALLETPAPY-LPATLVL-----GGE 4826 Query: 3336 AMPPEGIKAWRDAGLAQVELFNTYGPTEATVTASILSCAPYVSGQTVLP--AQMPIGAPL 3393 A P + R A Q +FN YGPTE TV + A + A +P+ L Sbjct: 4827 ATAPAQLARIR-ALAPQCRVFNHYGPTECTVGVLVHRAATEAEAEAEADPGASLPLTEAL 4885 Query: 3394 AGRKLRVLDAELSPLPIGVAGELCIGGELLARGYLNQPGLSAERFVADPLGDGGARLYRT 3453 +RVLDA+L P P G G+L +GG LARGYL+ E F+ DP G RLYR+ Sbjct: 4886 PHAYVRVLDAQLRPTPAGAIGQLWLGGAQLARGYLDAQQ-DREAFIDDPWLP-GRRLYRS 4943 Query: 3454 GDLVRWTHAGQLEYLGRIDHQVKIRGFRIEMGEIESIMLAQPEVREAVVVAR-EGVGSLQ 3512 GDL G + GR DHQVK+RGFRIE GEIE+ + QP VR+A+V+A +G Sbjct: 4944 GDLAVLLPQGGVRLAGRADHQVKVRGFRIEPGEIEAALRTQPGVRQALVLAAPDGA---- 4999 Query: 3513 LVAYVTPQHGRHIETAELRECLVRHLPDYMVPAALVVLPALPLNANGKVDRKALPEPVYE 3572 L A + HG+ + R L LP M P+ +VLP LP NGKVDRKAL E + Sbjct: 5000 LAACLAADHGQALPA--WRAALAEVLPAQMQPSRWLVLPELPRLGNGKVDRKALLEQLGR 5057 Query: 3573 SRTGH----EPPQGECEQALAAIWAEVLGLPAVGRHDNFFELGGHSLSILRIQSRIQQQF 3628 +G QG LA A++L PA+ +++FFELG HSL ++++ +RI+Q Sbjct: 5058 QDSGTPDVVAQAQGALAALLAQQMAQLLERPAIAANEDFFELGAHSLLVIKLIARIRQSL 5117 Query: 3629 PASALPLRSHFDHPT 3643 A P FDHP Sbjct: 5118 ALEAAPALV-FDHPN 5131 Score = 245 bits (625), Expect = 6e-65, Method: Compositional matrix adjust. Identities = 300/986 (30%), Positives = 435/986 (44%), Gaps = 112/986 (11%) Query: 515 VHEQIARQARRQPEATALLFGRQQLSYGALERRANQLAHRLIRLGAGPEVKVGIAVERSL 574 V + IA +A QP++ AL G L Y LERR LAH L LG P V + + R Sbjct: 4565 VAQMIAHRAAAQPQSPALAAGGAVLDYAGLERRVEHLAHALRSLGVAPGDIVALQLPRCA 4624 Query: 575 EMVIGLLGILKAGAAYVPLDPEYPAQRLQYMMQDSGMRLLLTQQ-HVLPTLPPLAGLPVL 633 E+V+ LL + GAAY+PLD + P R Q ++Q + + LL+ + LP A + Sbjct: 4625 ELVLALLATWRCGAAYLPLDTDSPVARRQQILQAAKVHLLVMEAGQSAEGLP--ADCTAV 4682 Query: 634 ALDQLDLDDEAHQPPAVRVHGENLAYVIYTSGSTGQPKGVANRHCALRNRLAWMQQAYRL 693 A D+L P + AYV++TSGSTG PKGV H L + + QA RL Sbjct: 4683 AWDELANSPVQASAPLPGSRMDATAYVLFTSGSTGAPKGVLIGHAQLAAYVQGVTQALRL 4742 Query: 694 EPHDTVLQKTPFSFDVSVWEFFWPLMIGARLALAQPGDHRDPARLVEQIQRHAVSTLHFV 753 + + D+ F L GA L +A D RD R + +++H + L V Sbjct: 4743 DACRHWALTGTVAADLGNTALFGALANGACLHVASAEDMRDGERFAKFLRQHGIDALKIV 4802 Query: 754 PSMLQAFLAHDEIEGCSSLHRLICSGEALPVEAQQGVFARLPQVALYNLYGPTEAAIDV- 812 PS L A L E L+ GEA + A PQ ++N YGPTE + V Sbjct: 4803 PSHLDALL---ETPAPYLPATLVLGGEATAPAQLARIRALAPQCRVFNHYGPTECTVGVL 4859 Query: 813 -------THWTCRADGRSQVPIGRPISSIRTLVLDGDLNLAPQGVPGELYLGGIGLARGY 865 AD + +P+ + VLD L P G G+L+LGG LARGY Sbjct: 4860 VHRAATEAEAEAEADPGASLPLTEALPHAYVRVLDAQLRPTPAGAIGQLWLGGAQLARGY 4919 Query: 866 LGRAGLSAERFVADPFSADGERLYRTGDLVRWNREGQLDYLGRLDHQVKIRGLRIELGEI 925 L A E F+ DP+ G RLYR+GDL +G + GR DHQVK+RG RIE GEI Sbjct: 4920 LD-AQQDREAFIDDPW-LPGRRLYRSGDLAVLLPQGGVRLAGRADHQVKVRGFRIEPGEI 4977 Query: 926 EARLLAQPGVREAVVVARESAGTSRLVAYVSGTDLVAATLRSALTKDLPDYMVPALIEVL 985 EA L QPGVR+A+V+A + +A G L A R+AL + LP M P+ VL Sbjct: 4978 EAALRTQPGVRQALVLAAPDGALAACLAADHGQALPA--WRAALAEVLPAQMQPSRWLVL 5035 Query: 986 EHLPLNANGKVDRRALPDPAQPLQRAYEAPRGQAEQVLAAVWAEVLGLQQ---------- 1035 LP NGKVDR+AL L++ G + V A A L Q Sbjct: 5036 PELPRLGNGKVDRKAL------LEQLGRQDSGTPDVVAQAQGALAALLAQQMAQLLERPA 5089 Query: 1036 VGRHDNFFELGGDSILSLQIVAGLRRR-GSQLAPRLIFER-----------------QTI 1077 + +++FFELG S+L ++++A +R+ + AP L+F+ + Sbjct: 5090 IAANEDFFELGAHSLLVIKLIARIRQSLALEAAPALVFDHPNAIALAAALQAAAPDPDAL 5149 Query: 1078 AQLAPAIAHSTAP-QLHAQVSVQGELPLLPIQAEFFAMD---------IPVRHHWNQSIL 1127 +LA + S AP Q + ++ P + + +M+ P+ + Q Sbjct: 5150 ERLAQSRLESAAPAQADSMNALTAGFPARHTRIPYRSMNDMSRPPHEHAPLSYSQQQLWF 5209 Query: 1128 LATDAP----------------LDMAALNTALQAVVAHHDSLRLRYTRDDQGQWRQTYGQ 1171 L P LD AAL+ AL A+ A H LR R+ D Y Q Sbjct: 5210 LQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAETDG----LPYQQ 5265 Query: 1172 HDPAQLRELLW--VRQGLPGNAIAPLCEQAQRS----LNLARGPLL--RAVAMELEEGGW 1223 P +L W +RQ P L E+ Q + +L + L R +A+ +E Sbjct: 5266 AVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLIALGPQE--- 5322 Query: 1224 RLLLVIHH-LVVDGVSWRILLADLQQAYRQCVALEPLVLPARTASYQQWAHVLQGR-HGA 1281 +L++ H +V D S +++ DL +AYRQ LPA Y +AH + R GA Sbjct: 5323 HVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQRQRVQGA 5382 Query: 1282 LLPQR-PYWQAQMQPPSV---LPCDDAGGEATMRQRQEMSFGLDKERTNALLRRVPAAYR 1337 L YW + P + LP D + +F LD +AL +++ A R Sbjct: 5383 WLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLD----SALAQQMQAFCR 5438 Query: 1338 TRIND---VLLTALVRALCGWSGLSEIQVDIEGHGREDGTGQLDLSRTVGWF--TSVFPL 1392 + L+ A L +SG S+ V GR +L VG+F T ++ Sbjct: 5439 AQHCTPFVALMAAWQVLLSRYSGQSDFLVGAPNAGRNHA----ELQDLVGFFVTTQLYRA 5494 Query: 1393 RLSGAGTPQQALKRIKESLRAVPEAG 1418 RL+ T ++ +++++ + A E G Sbjct: 5495 RLTPELTVRELVRQVRGDMLAALEHG 5520 Score = 97.4 bits (241), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 239/945 (25%), Positives = 370/945 (39%), Gaps = 146/945 (15%) Query: 535 GRQQLSYGALERRANQLAHRLI-RLGAGPEVKVGIAVERSLEMVIGLLGILKAGAAYVPL 593 G ++ S+ L+ RA A R G +V + +E V LG L AG VP+ Sbjct: 50 GERRFSFAQLDLRARAYAAAFQQRCPRG--ARVLLVLENDEHYVQAFLGCLYAGMVAVPV 107 Query: 594 DPEYPA-----QRLQYMMQDSGMRLLLTQQHVLPTLPPLA---GLPVLALDQLDLDDEAH 645 P +RL + D+ ++ + + T A +LA +Q+ D H Sbjct: 108 FPPESVRPQHLKRLAGIAADAQAACVVLPEPLRQTCAQAALFGAAELLAAEQVADADAVH 167 Query: 646 QPPAVRVHG---ENLAYVIYTSGSTGQPKGVANRHCALRNRLAWMQQAYRLEPHDTVLQK 702 R H +++A++ YTSGST PKGV H L A + R+ D + Sbjct: 168 W----REHTPQPQDIAFLQYTSGSTSAPKGVMVSHGNLMANEAAISACMRVREDDIFVTW 223 Query: 703 TPFSFDVSVWEFFWPLMI-GARLALAQPGDHRD-PARLVEQIQRHAVSTL---HFVPSML 757 P D+ + ++ G + L P + P R +E + RH + F + Sbjct: 224 LPLYHDMGLIGGLLQGLVRGLKTVLCSPRYFLERPLRWLELVARHRGTVSGGPDFAYRLC 283 Query: 758 QAFLAHDEIEGC--SSLHRLICSGEAL-----PVEAQQGVFARLPQVALYNLYGPTEAAI 810 + ++ G SS C E L P ++ A A Y YG EA + Sbjct: 284 VERIKPAQLPGVDLSSWRVAFCGAEPLRADTFPAFIERFSVAGFSADAAYPCYGLAEATL 343 Query: 811 DVT-------HWTCRADGRSQVPIGRPISS---IRTLVLDGDL------------NLAPQ 848 V+ H T A +++ GR + LV GD+ + Sbjct: 344 IVSGGPPHGAHAT--AFHTAELAAGRAVEGGPDDTRLVACGDIAPHHEVRIIEDGRVQQD 401 Query: 849 GVPGELYLGGIGLARGYLGRAGLSAERFVADPFSADGERLYRTGDLVRWNREGQLDYLGR 908 G GE+ + G + +GY R SA FV DG R RTGDL + R+GQL GR Sbjct: 402 GAVGEIEVCGPSVTQGYWQRPQESAAAFV----ERDGRRWLRTGDL-GFLRDGQLYIAGR 456 Query: 909 LDHQVKIRGLRIELGEIE---------------ARLLAQPGVREAVVVARESAGTSRLVA 953 + +RG + +IE A G E + VA E SR + Sbjct: 457 RKDLIIVRGQNVYPQDIERAVEDQVEAVRKGRVAAFAVNTGDGEGIGVAAE---ISRGMQ 513 Query: 954 YVSGTDLVAATLRSALTKDLPDYMVPALIEVLE--HLPLNANGKVDR------------- 998 ++ +A+ + A+ + P ++ +L LP ++GK+ R Sbjct: 514 KLAAPGAIASAIAEAVAQ--ASLEAPQVVILLNPGGLPKTSSGKLQRSACRSGWRNGELD 571 Query: 999 ----------RALPDPAQPLQRAYEAPRGQAEQVLAAVWAEVLGLQQVGRHDNFFELGGD 1048 +A P AQ + E P+G E LAA+W L GR +FF GG Sbjct: 572 AWAIVEEGELKAGPSDAQGGELLAEPPQGDIETALAAIWQSALKRAIAGRQADFFRSGGS 631 Query: 1049 SILSLQIVAGLRRRGS-QLAPRLIFERQTIAQLAPAI-----AHSTAPQLHAQVSVQGEL 1102 S+ ++Q+VA + R + P ++F T+A A I A + A L A V Q E Sbjct: 632 SLAAMQVVAAVVDRWQVEFTPAMLFAAPTLAASAAQIAALLEAGAQAAPLPACVDGQSEF 691 Query: 1103 PLLPIQAEFFAM--DIPVRHHWNQSILLATDAPLDMAALNTALQAVVAHHDSLRLRYTRD 1160 PL Q + P +N + +L L + AL AL + A H +LR + Sbjct: 692 PLTQAQQGLWLTWQLQPDSAAYNLAGVLDLRGELQVEALEDALCDLAARHAALRTLFPLR 751 Query: 1161 DQGQWRQTYGQHDPAQLRELLWVRQGL---PGNAIAPLCEQA-----QRSLNLARGPLLR 1212 D +Q D + R +L +R L P + A A ++ L LR Sbjct: 752 DGTPVQQVL---DIDEARPML-LRSDLRRQPADKRAQAAASALQRFHAQAFRLDSETPLR 807 Query: 1213 AVAMELEEGGWRLLLVIHHLVVDGVSWRILLADLQQAYR-QCVALEPL--VLPARTASYQ 1269 A+ ++LE +RL L IHH+ DG S I+L +L AY +C P L + Y Sbjct: 808 AMLVQLEPHHFRLGLCIHHIAADGWSLGIILDELTAAYEARCAGAAPSWPALELQPGDYA 867 Query: 1270 QWAHVLQGRHGALLPQR--PYWQAQMQ-PPSVLP--------CDDAGGEATMRQRQEMSF 1318 W + + G+ QR YW+A+++ P++LP GGE R R + Sbjct: 868 VWQRQ-RSQPGSPEFQRQLDYWRARLEGAPALLPLPTDRPRQAGAHGGEGQHRWRLSAAL 926 Query: 1319 GLDKERTNALLRRVPAAYRTRINDVLLTALVRALCGWSGLSEIQV 1363 + LR++ A+ + +L AL SG S++ V Sbjct: 927 -------STALRKLAASQGVTLYGAVLALFTLALQRLSGQSDLCV 964 Score = 92.8 bits (229), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 167/611 (27%), Positives = 240/611 (39%), Gaps = 100/611 (16%) Query: 3083 VALISGNRSMSYGQLNTRVNQLAHYLLQRGLQPEARVGVALERSADMVVAVLAILKAGAT 3142 VA SG R S+ QL+ R A QR + ARV + LE V A L L AG Sbjct: 45 VADASGERRFSFAQLDLRARAYAAAFQQRCPR-GARVLLVLENDEHYVQAFLGCLYAGMV 103 Query: 3143 YVPLDPDYPV-----QRLAAIIEDSALSLL-----LSQTSVSQRLPGGR----AEQTLYL 3188 VP+ P V +RLA I D+ + + L QT L G AEQ Sbjct: 104 AVPVFPPESVRPQHLKRLAGIAADAQAACVVLPEPLRQTCAQAALFGAAELLAAEQVADA 163 Query: 3189 DQLDLQA---QPHDEPDVTIHSDSLAYVIYTSGSTGRPKGVGISHRCLMEHGQIAADFFG 3245 D + + QP D +A++ YTSGST PKGV +SH LM + + Sbjct: 164 DAVHWREHTPQPQD----------IAFLQYTSGSTSAPKGVMVSHGNLMANEAAISACMR 213 Query: 3246 LTPQDCMLQFSTLNFDGCIEQLFPPLLV-GAAVVLRGPELWDSQRLH-VELLA-HRISVL 3302 + D + + L D + LV G VL P + + L +EL+A HR +V Sbjct: 214 VREDDIFVTWLPLYHDMGLIGGLLQGLVRGLKTVLCSPRYFLERPLRWLELVARHRGTVS 273 Query: 3303 DLTTAYWLLLVQDFARMGVP--DYGVLRRVHVGGEAMP----PEGIKAWRDAGLAQVELF 3356 + L V+ +P D R G E + P I+ + AG + + Sbjct: 274 GGPDFAYRLCVERIKPAQLPGVDLSSWRVAFCGAEPLRADTFPAFIERFSVAGFSADAAY 333 Query: 3357 NTYGPTEATVTASILSCAPYVSGQTVL-PAQMPIGAPLAG----------------RKLR 3399 YG EAT+ S P+ + T A++ G + G ++R Sbjct: 334 PCYGLAEATLIVS--GGPPHGAHATAFHTAELAAGRAVEGGPDDTRLVACGDIAPHHEVR 391 Query: 3400 VLDAELSPLPIGVAGELCIGGELLARGYLNQPGLSAERFVADPLGDGGARLYRTGDLVRW 3459 +++ + G GE+ + G + +GY +P SA FV G R RTGDL + Sbjct: 392 IIE-DGRVQQDGAVGEIEVCGPSVTQGYWQRPQESAAAFVER----DGRRWLRTGDL-GF 445 Query: 3460 THAGQLEYLGRIDHQVKIRGFRIEMGEIESIMLAQPE-VREAVVVA-------REGVGSL 3511 GQL GR + +RG + +IE + Q E VR+ V A EG+G Sbjct: 446 LRDGQLYIAGRRKDLIIVRGQNVYPQDIERAVEDQVEAVRKGRVAAFAVNTGDGEGIG-- 503 Query: 3512 QLVAYVTPQHGRHIETAELRECLVRHLPDYMVPAALVVL----PALPLNANGKVDR---- 3563 + A ++ + + + + + A VV+ LP ++GK+ R Sbjct: 504 -VAAEISRGMQKLAAPGAIASAIAEAVAQASLEAPQVVILLNPGGLPKTSSGKLQRSACR 562 Query: 3564 -------------------KALPEPVYESRTGHEPPQGECEQALAAIWAEVLGLPAVGRH 3604 KA P EPPQG+ E ALAAIW L GR Sbjct: 563 SGWRNGELDAWAIVEEGELKAGPSDAQGGELLAEPPQGDIETALAAIWQSALKRAIAGRQ 622 Query: 3605 DNFFELGGHSL 3615 +FF GG SL Sbjct: 623 ADFFRSGGSSL 633 >gi|300312041|ref|YP_003776133.1| acyl-CoA synthetase/AMP-acid ligase II protein [Herbaspirillum seropedicae SmR1] Length = 539 Score = 157 bits (398), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 174/549 (31%), Positives = 247/549 (44%), Gaps = 72/549 (13%) Query: 3064 TPAVITTRIAQRASIQPDAVALISGNRSMSYGQLNTRVNQLAHYLLQRGLQPEARVGVAL 3123 TP +I + A +P A AL + + Y L V Q+A LL GL P RV V L Sbjct: 2 TPTLIHDTLLASAQARPQATALRYRGQQLDYAGLAAGVEQVAAALLALGLGPGERVAVYL 61 Query: 3124 ERSADMVVAVLAILKAGATYVPLDPDYPVQRLAAIIEDSALSLLLS----QTSVSQRLPG 3179 E+ + V+A+ AG +VP++P +++ I++D A+ +L+S +++ RL Sbjct: 62 EKRMETVLALFGAAAAGLVFVPINPLLKPAQVSHILQDCAVRVLVSSEPRHPALADRLSQ 121 Query: 3180 GRAEQTLYL--------------------DQLD----LQAQP-------HDEPDVTIHSD 3208 A QT+ L LD LQA P H D I Sbjct: 122 CPALQTVVLVDAAAAAPATPAPPAPLGRLATLDWNAFLQAAPGPGSRRAHRRIDADI--- 178 Query: 3209 SLAYVIYTSGSTGRPKGVGISHRCLMEHGQIAADFFGLTPQDCMLQFSTLNFDGCIEQLF 3268 A ++YTSGSTG+PKGV +SHR L+ Q A + G PQD +L L+FD + QL Sbjct: 179 --AAILYTSGSTGQPKGVVLSHRNLVAGAQSVAGYLGNHPQDRLLAVLPLSFDYGLSQLS 236 Query: 3269 PPLLVGAAVVLRGPELWDSQRLHVELLAHRISVLDLTTAYWLLLVQDFARMGVPDYGVLR 3328 L GA+V L L LH + + I+ L W Q A + P LR Sbjct: 237 TAFLSGASVTLLN-YLAPRDILHA-VASEGITGLAGVPPLW----QQLAGLPWPQGCSLR 290 Query: 3329 RVHVGGEAMPPEGIKAWRDAGLAQVELFNTYGPTEATVTASILSCAPYVSGQTVLPAQM- 3387 + G A+P + R A L Q ++F YG TEA + + PA++ Sbjct: 291 YLTNSGGALPRSVLAQLRRA-LPQAQVFLMYGLTEAFRSTYL------------PPAELD 337 Query: 3388 ----PIGAPLAGRKLRVLDAELSPLPIGVAGELCIGGELLARGYLNQPGLSAERFVADP- 3442 IG + ++ V+ + SP G GEL G L+A+GY N P +AERF P Sbjct: 338 RRPDSIGRAIPNAEIMVVRPDGSPCAPGEVGELVHRGALVAQGYWNDPARTAERFRPAPG 397 Query: 3443 ----LGDGGARLYRTGDLVRWTHAGQLEYLGRIDHQVKIRGFRIEMGEIESIMLAQPEVR 3498 LG ++ +GD VR G L ++GR D +K+ G+RI E+E ++ A Sbjct: 398 REAALGTPELAVW-SGDSVRMDEQGYLYFVGRADDMIKVSGYRISPHEVEEVLHATGLAD 456 Query: 3499 EAVVVAREGVGSLQLVAYVTPQHGRHIETAELRECLVRHLPDYMVPAALVVLPA-LPLNA 3557 + VV Q V V P A + C HLP YM+PAAL P LP + Sbjct: 457 QFAVVGVAHPQQGQAVVAVVPSSCTASLEAVQQACRA-HLPSYMLPAALHRWPGELPRSP 515 Query: 3558 NGKVDRKAL 3566 NGK+DRK + Sbjct: 516 NGKLDRKLM 524 Score = 147 bits (370), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 154/527 (29%), Positives = 234/527 (44%), Gaps = 48/527 (9%) Query: 515 VHEQIARQARRQPEATALLFGRQQLSYGALERRANQLAHRLIRLGAGPEVKVGIAVERSL 574 +H+ + A+ +P+ATAL + QQL Y L Q+A L+ LG GP +V + +E+ + Sbjct: 6 IHDTLLASAQARPQATALRYRGQQLDYAGLAAGVEQVAAALLALGLGPGERVAVYLEKRM 65 Query: 575 EMVIGLLGILKAGAAYVPLDPEYPAQRLQYMMQDSGMRLLLTQQHVLPTLPP-LAGLPVL 633 E V+ L G AG +VP++P ++ +++QD +R+L++ + P L L+ P L Sbjct: 66 ETVLALFGAAAAGLVFVPINPLLKPAQVSHILQDCAVRVLVSSEPRHPALADRLSQCPAL 125 Query: 634 --------------------------ALDQLDLDDEAHQPPAVRVH---GENLAYVIYTS 664 LD A P + R H ++A ++YTS Sbjct: 126 QTVVLVDAAAAAPATPAPPAPLGRLATLDWNAFLQAAPGPGSRRAHRRIDADIAAILYTS 185 Query: 665 GSTGQPKGVANRHCALRNRLAWMQQAYRL---EPHDTVLQKTPFSFDVSVWEFFWPLMIG 721 GSTGQPKGV H RN +A Q P D +L P SFD + + + G Sbjct: 186 GSTGQPKGVVLSH---RNLVAGAQSVAGYLGNHPQDRLLAVLPLSFDYGLSQLSTAFLSG 242 Query: 722 ARLALAQPGDHRDPARLVEQIQRHAVSTLHFVPSMLQAFLAHDEIEGCSSLHRLICSGEA 781 A + L ++ P ++ + ++ L VP + Q +GCS L L SG A Sbjct: 243 ASVTLL---NYLAPRDILHAVASEGITGLAGVPPLWQQLAGLPWPQGCS-LRYLTNSGGA 298 Query: 782 LPVEAQQGVFARLPQVALYNLYGPTEAAIDVTHWTCRADGRSQVPIGRPISSIRTLVLDG 841 LP + LPQ ++ +YG TEA D R IGR I + +V+ Sbjct: 299 LPRSVLAQLRRALPQAQVFLMYGLTEAFRSTYLPPAELDRRPDS-IGRAIPNAEIMVVRP 357 Query: 842 DLNLAPQGVPGELYLGGIGLARGYLGRAGLSAERFVADPFS----ADGERLYRTGDLVRW 897 D + G GEL G +A+GY +AERF P E +GD VR Sbjct: 358 DGSPCAPGEVGELVHRGALVAQGYWNDPARTAERFRPAPGREAALGTPELAVWSGDSVRM 417 Query: 898 NREGQLDYLGRLDHQVKIRGLRIELGEIEARLLAQPGVREAVVVARESAGTSRLVAYVSG 957 + +G L ++GR D +K+ G RI E+E L A + VV + V V Sbjct: 418 DEQGYLYFVGRADDMIKVSGYRISPHEVEEVLHATGLADQFAVVGVAHPQQGQAVVAVVP 477 Query: 958 TDLVAA--TLRSALTKDLPDYMVPALIEVLE-HLPLNANGKVDRRAL 1001 + A+ ++ A LP YM+PA + LP + NGK+DR+ + Sbjct: 478 SSCTASLEAVQQACRAHLPSYMLPAALHRWPGELPRSPNGKLDRKLM 524 Score = 124 bits (311), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 165/550 (30%), Positives = 231/550 (42%), Gaps = 74/550 (13%) Query: 1995 PTIRADDVIERWAAQVSQQPGAAALTDGNHALDMAGLCAWVEQMAQQMRQRGIGCEDRVA 2054 PT+ D ++ A +P A AL LD AGL A VEQ+A + G+G +RVA Sbjct: 3 PTLIHDTLL----ASAQARPQATALRYRGQQLDYAGLAAGVEQVAAALLALGLGPGERVA 58 Query: 2055 IHAERSCAFVVAVLATLRVGAAYVPLDPALPAERLHYQLQDSAAVLLLSA-----TAPDW 2109 ++ E+ V+A+ G +VP++P L ++ + LQD A +L+S+ D Sbjct: 59 VYLEKRMETVLALFGAAAAGLVFVPINPLLKPAQVSHILQDCAVRVLVSSEPRHPALADR 118 Query: 2110 AASVPVLPLASL--------------HGVPKRVPYCWPAV-----HPGQ----------A 2140 + P L L + + W A PG Sbjct: 119 LSQCPALQTVVLVDAAAAAPATPAPPAPLGRLATLDWNAFLQAAPGPGSRRAHRRIDADI 178 Query: 2141 AYVIYTSGSTGRPKGVVVSRGALANYVAGVLERLDLREQDRSMAMVSTVGADLGHTVLFG 2200 A ++YTSGSTG+PKGVV+S L V L QDR +A++ + D G + L Sbjct: 179 AAILYTSGSTGQPKGVVLSHRNLVAGAQSVAGYLGNHPQDRLLAVLP-LSFDYGLSQLST 237 Query: 2201 ALCSGRLLHLIPPQCSFDPDAMASYMEQHQVDVLKIVPSHLQALLHAASPASVLPRSRLV 2260 A SG + L+ P + + + L VP Q L P R Sbjct: 238 AFLSGASVTLL---NYLAPRDILHAVASEGITGLAGVPPLWQQLAGLPWPQGCSLRYLTN 294 Query: 2261 LGGEASRKPLLAHIASLRPQCRVMNHYGPTETTVGVLTQEASSALDEADSLP--IGQPIA 2318 GG R +LA + PQ +V YG TE A E D P IG+ I Sbjct: 295 SGGALPRS-VLAQLRRALPQAQVFLMYGLTEAFRSTYLPPA-----ELDRRPDSIGRAIP 348 Query: 2319 QARAYVLDAELQPVPQGVAGELYLAGHGVARAYQQRPAQSAERF------VADLLEPGQR 2372 A V+ + P G GEL G VA+ Y PA++AERF A L P Sbjct: 349 NAEIMVVRPDGSPCAPGEVGELVHRGALVAQGYWNDPARTAERFRPAPGREAALGTPELA 408 Query: 2373 MYRSGDRVRQLADGSLEFLGRLDGQIKVRGYRVELREIAALLQSLEAVAQAEVVVHSEPA 2432 ++ SGD VR G L F+GR D IKV GYR+ E+ +L + Q VV + P Sbjct: 409 VW-SGDSVRMDEQGYLYFVGRADDMIKVSGYRISPHEVEEVLHATGLADQFAVVGVAHPQ 467 Query: 2433 QPGPDGEEVAPQIIAYLVPMGGQTLDVADLRQQLATRLPDYMMPTALVPLH----VMPLT 2488 Q Q + +VP T + ++Q LP YM+P A LH +P + Sbjct: 468 Q---------GQAVVAVVP-SSCTASLEAVQQACRAHLPSYMLPAA---LHRWPGELPRS 514 Query: 2489 PNGKLDRQAL 2498 PNGKLDR+ + Sbjct: 515 PNGKLDRKLM 524 >gi|300309365|ref|YP_003773457.1| acetyl-coenzyme A synthetase [Herbaspirillum seropedicae SmR1] Length = 549 Score = 126 bits (317), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 152/515 (29%), Positives = 228/515 (44%), Gaps = 67/515 (13%) Query: 3091 SMSYGQLNTRVNQLAHYLLQRGLQPEARVGVALERSADMVVAVLAILKAGATYVPL---- 3146 S SY QL ++ A+ L G+ R+G+ L + + V+ LA K GA VPL Sbjct: 62 SYSYDQLKILSDRFANALRAAGVGRGDRIGIYLSQRIETVITHLAAYKLGAITVPLFYLF 121 Query: 3147 DPDYPVQRL-----AAIIEDS-------------ALSLLLSQTSVSQRLPGGRAEQTLYL 3188 PD RL A++ D+ AL L+ S LP + T + Sbjct: 122 GPDAIAYRLDNSGAVALVTDASGMEKATLAGELPALRLVFCVESSDLVLP----QTTDFW 177 Query: 3189 DQLDLQAQPHDEPDVTIHSDSLAYVIYTSGSTGRPKGVGISHRCLMEH---GQIAADFFG 3245 D+L A P + V +D A +IYTSG+TG+ KG +HR L+ H +++ D F Sbjct: 178 DRL--HAAPAELDPVLTLADDPAMIIYTSGTTGKAKGALHAHRVLLGHLPGVEVSHDSF- 234 Query: 3246 LTPQDCMLQFSTLNF---DGCIEQLFPPLLVGAAVVLRGPELWDSQRLHVELLAHRI-SV 3301 PQ+ ++ ++ G ++ L P L G AVV R E +D+ + L H+I +V Sbjct: 235 --PQEGDRFWTPADWAWIGGLLDVLLPSLYHGVAVVARRLEKFDAAEVFGLLARHQIRNV 292 Query: 3302 LDLTTAYWLLLVQDFARMGVPDYGVLRRVHVGGEAMPPEGIKAWRDAGLAQVELFNTYGP 3361 TA +L R D+ LR V GGE + + I R+A + F YG Sbjct: 293 FFPPTALKMLRGAATVRAQA-DFS-LRSVASGGETLGDDLIAWGREALGVTINEF--YGQ 348 Query: 3362 TEATVTASILS-CAPYVSGQTVLPAQMPIGAPLAGRKLRVLDAELSPLPIGVAGELCIGG 3420 TE + S S C P VSG +G + G ++++D + LP G G + I Sbjct: 349 TECNLVVSSSSHCYPSVSGS--------MGRAVPGHVVQIVDEQGQVLPHGTVGNIAIRA 400 Query: 3421 E---LLARGYLNQPGLSAERFVADPLGDGGARLYRTGDLVRWTHAGQLEYLGRIDHQVKI 3477 + R + N+ + E+F D L TGDL G + YLGR D + Sbjct: 401 PDPVMFLRYWRNEEA-TREKFAGDFL--------LTGDLGSMDEQGYIRYLGRNDDVITS 451 Query: 3478 RGFRIEMGEIESIMLAQPEVREAVVVAREGVGSLQLV-AYVTPQHGRHIE---TAELREC 3533 G+RI IE ++ P VR A VV + ++V A+V + G + AEL++ Sbjct: 452 AGYRIGPAAIEECLMRHPAVRIAAVVGVKDALRTEVVKAFVVLKDGVTPDEALKAELQQH 511 Query: 3534 LVRHLPDYMVPAALVVLPALPLNANGKVDRKALPE 3568 + L + P + + ALP A GK+ RK L E Sbjct: 512 VRAQLAAHEYPRLISFVAALPTTATGKIMRKTLKE 546 Score = 97.1 bits (240), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 126/500 (25%), Positives = 201/500 (40%), Gaps = 47/500 (9%) Query: 540 SYGALERRANQLAHRLIRLGAGPEVKVGIAVERSLEMVIGLLGILKAGAAYVPLDPEYPA 599 SY L+ +++ A+ L G G ++GI + + +E VI L K GA VPL + Sbjct: 64 SYDQLKILSDRFANALRAAGVGRGDRIGIYLSQRIETVITHLAAYKLGAITVPLFYLFGP 123 Query: 600 QRLQYMMQDSGMRLLLTQQHVLPTLPPLAGLPVLAL------------DQLDLDDEAHQP 647 + Y + +SG L+T + LP L L D D H Sbjct: 124 DAIAYRLDNSGAVALVTDASGMEKATLAGELPALRLVFCVESSDLVLPQTTDFWDRLHAA 183 Query: 648 PA----VRVHGENLAYVIYTSGSTGQPKGVANRHCALRNRLAWMQQAYRLEPHDTVLQKT 703 PA V ++ A +IYTSG+TG+ KG + H L L ++ ++ P + T Sbjct: 184 PAELDPVLTLADDPAMIIYTSGTTGKAKGALHAHRVLLGHLPGVEVSHDSFPQEGDRFWT 243 Query: 704 P--FSFDVSVWEFFWPLMIGARLALAQPGDHRDPARLVEQIQRHAVSTLHFVPSMLQAFL 761 P +++ + + P + +A+ + D A + + RH + + F P+ L+ Sbjct: 244 PADWAWIGGLLDVLLPSLYHGVAVVARRLEKFDAAEVFGLLARHQIRNVFFPPTALKMLR 303 Query: 762 AHDEIEGCS--SLHRLICSGEALPVEAQQGVFARLPQVALYNLYGPTEAAIDV---THWT 816 + + SL + GE L + L V + YG TE + V +H Sbjct: 304 GAATVRAQADFSLRSVASGGETLGDDLIAWGREAL-GVTINEFYGQTECNLVVSSSSHCY 362 Query: 817 CRADGRSQVPIGRPISSIRTLVLDGDLNLAPQGVPGELYLGG---IGLARGYLGRAGLSA 873 G +GR + ++D + P G G + + + R Y + Sbjct: 363 PSVSGS----MGRAVPGHVVQIVDEQGQVLPHGTVGNIAIRAPDPVMFLR-YWRNEEATR 417 Query: 874 ERFVADPFSADGERLYRTGDLVRWNREGQLDYLGRLDHQVKIRGLRIELGEIEARLLAQP 933 E+F D TGDL + +G + YLGR D + G RI IE L+ P Sbjct: 418 EKFAGD--------FLLTGDLGSMDEQGYIRYLGRNDDVITSAGYRIGPAAIEECLMRHP 469 Query: 934 GVREAVVVARESAGTSRLV-AYVSGTDLVA------ATLRSALTKDLPDYMVPALIEVLE 986 VR A VV + A + +V A+V D V A L+ + L + P LI + Sbjct: 470 AVRIAAVVGVKDALRTEVVKAFVVLKDGVTPDEALKAELQQHVRAQLAAHEYPRLISFVA 529 Query: 987 HLPLNANGKVDRRALPDPAQ 1006 LP A GK+ R+ L + Q Sbjct: 530 ALPTTATGKIMRKTLKEMDQ 549 Score = 77.0 bits (188), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 125/503 (24%), Positives = 205/503 (40%), Gaps = 63/503 (12%) Query: 2036 EQMAQQMRQRGIGCEDRVAIHAERSCAFVVAVLATLRVGAAYVPLDPALPAERLHYQLQD 2095 ++ A +R G+G DR+ I+ + V+ LA ++GA VPL + + Y+L + Sbjct: 73 DRFANALRAAGVGRGDRIGIYLSQRIETVITHLAAYKLGAITVPLFYLFGPDAIAYRLDN 132 Query: 2096 SAAVLLLSATA----PDWAASVPVLPL-----ASLHGVPKRVPYCWPAVHPGQA------ 2140 S AV L++ + A +P L L +S +P+ + W +H A Sbjct: 133 SGAVALVTDASGMEKATLAGELPALRLVFCVESSDLVLPQTTDF-WDRLHAAPAELDPVL 191 Query: 2141 ------AYVIYTSGSTGRPKGVVVSRGALANYVAGVLERLDL--REQDR-----SMAMVS 2187 A +IYTSG+TG+ KG + + L ++ GV D +E DR A + Sbjct: 192 TLADDPAMIIYTSGTTGKAKGALHAHRVLLGHLPGVEVSHDSFPQEGDRFWTPADWAWIG 251 Query: 2188 TVGADLGHTVLFGALCSGRLLHLIPPQCSFDPDAMASYMEQHQVDVLKIVPSHLQALLHA 2247 + L ++ G R L FD + + +HQ+ + P+ L+ L A Sbjct: 252 GLLDVLLPSLYHGVAVVARRLE------KFDAAEVFGLLARHQIRNVFFPPTALKMLRGA 305 Query: 2248 AS---PASVLPRSRLVLGGEASRKPLLAHIASLRPQCRVMNHYGPTETTVGVLTQEASSA 2304 A+ A RS + GGE L+A + YG TE L +SS Sbjct: 306 ATVRAQADFSLRS-VASGGETLGDDLIAW-GREALGVTINEFYGQTECN---LVVSSSSH 360 Query: 2305 LDEADSLPIGQPIAQARAYVLDAELQPVPQGVAGELYLAGHG--VARAYQQRPAQSAERF 2362 + S +G+ + ++D + Q +P G G + + + Y + + E+F Sbjct: 361 CYPSVSGSMGRAVPGHVVQIVDEQGQVLPHGTVGNIAIRAPDPVMFLRYWRNEEATREKF 420 Query: 2363 VADLLEPGQRMYRSGDRVRQLADGSLEFLGRLDGQIKVRGYRVELREIAALLQSLEAVAQ 2422 D L +GD G + +LGR D I GYR+ I L AV Sbjct: 421 AGDFL-------LTGDLGSMDEQGYIRYLGRNDDVITSAGYRIGPAAIEECLMRHPAVRI 473 Query: 2423 AEVVVHSEPAQPGPDGEEVAPQIIAYLVPMGGQTLD---VADLRQQLATRLPDYMMPTAL 2479 A VV + + EV + A++V G T D A+L+Q + +L + P + Sbjct: 474 AAVVGVKDALR-----TEV---VKAFVVLKDGVTPDEALKAELQQHVRAQLAAHEYPRLI 525 Query: 2480 VPLHVMPLTPNGKLDRQALPRPD 2502 + +P T GK+ R+ L D Sbjct: 526 SFVAALPTTATGKIMRKTLKEMD 548 >gi|300313157|ref|YP_003777249.1| long-chain-fatty-acid-CoA ligase [Herbaspirillum seropedicae SmR1] Length = 566 Score = 94.7 bits (234), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 132/564 (23%), Positives = 222/564 (39%), Gaps = 81/564 (14%) Query: 507 QHAEVMEPVHEQIARQARRQPEATALLFGRQQLSYGALERRANQLAHRLIRLGAGPEVKV 566 ++ +++ + E + A RQ A + + LSY L+ + L L LG +V Sbjct: 21 RYGSLVQMIDEAFVQHADRQ----AYVCMGKYLSYRELDSLSRALGGWLQGLGLQKGARV 76 Query: 567 GIAVERSLEMVIGLLGILKAGAAYVPLDPEYPAQRLQYMMQDSGMRLLLTQQHVLPTLPP 626 I + L+ I + IL+AG V ++P Y A+ L++ ++DSG + ++ TL Sbjct: 77 AIMMPNVLQYPIAIAAILRAGYTVVNVNPLYTARELEHQLKDSGAEAIFVLENFACTLQK 136 Query: 627 LAG----------------------------------LPVLAL-DQLDLDDEAHQP---- 647 + +P +L + + Q Sbjct: 137 VVAHTNIKHIVVASMGELLGALKGTLVNLVVRHVKKLVPAWSLPNAITFSQALSQARGKT 196 Query: 648 --PAVRVHGENLAYVIYTSGSTGQPKGVANRHCALRNRLA-------WMQQAYRL-EPHD 697 P H +++A++ YT G+TG KG H RN +A W+ A + +P D Sbjct: 197 LQPVTLTH-DDIAFLQYTGGTTGVAKGAVLTH---RNLVANVLQAEEWLTPALKAGKPID 252 Query: 698 TVLQKTPFSFDVSVWEFFWPL---MIGAR---LALAQPGDHRDPARLVEQIQRHAVSTLH 751 ++ F + ++ F M+G R L L P + RD V+++ ++ V+T Sbjct: 253 QLV----FVCALPLYHIFALTVCNMLGTREGALNLLIP-NPRDIPGFVKELAKYKVNTFP 307 Query: 752 FVPSMLQAFLAHDEIEGCSSLHRLICSGEALPVEAQQG-VFARLPQVALYNLYGPTEAAI 810 V ++ A L + + C G + V+ + +L + YG +E + Sbjct: 308 AVNTLYNALLNNADFARLDFSGYRCCVGGGMAVQKSVADKWKKLTGCPIIEGYGLSETSP 367 Query: 811 DVTHWTCRADGRSQVPIGRPISSIRTLVLDGDLNLAPQGVPGELYLGGIGLARGYLGRAG 870 + C D + IG P+ S +LD D P G PGE+ + G + GY R Sbjct: 368 IASANPCTIDEYTGT-IGLPLPSTEFAILDDDGQPVPLGQPGEIAIRGPQVMPGYWQRPD 426 Query: 871 LSAERFVADPFSADGERLYRTGDLVRWNREGQLDYLGRLDHQVKIRGLRIELGEIEARLL 930 +A+ D F ++TGD+ + G + R + + G + E+E + Sbjct: 427 ETAKVMTPDGF-------FKTGDIGVMDERGYTKIVDRKKDMILVSGFNVYPNEVEGVVA 479 Query: 931 AQPGVREAVVVARESAGTSRLVA-YVSGTD--LVAATLRSALTKDLPDYMVPALIEVLEH 987 PGV E V T V +V D L AA L + Y P IE + Sbjct: 480 QHPGVLECACVGVPDEHTGEAVKLFVVRKDKTLSAAQLMDYCKEQFTGYKKPKYIEFRDE 539 Query: 988 LPLNANGKVDRRALPD-PAQPLQR 1010 LP GK+ RR L D PA+ Q+ Sbjct: 540 LPKTNVGKILRRELRDEPAKAQQK 563 Score = 90.5 bits (223), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 123/544 (22%), Positives = 205/544 (37%), Gaps = 86/544 (15%) Query: 3081 DAVALISGNRSMSYGQLNTRVNQLAHYLLQRGLQPEARVGVALERSADMVVAVLAILKAG 3140 D A + + +SY +L++ L +L GLQ ARV + + +A+ AIL+AG Sbjct: 38 DRQAYVCMGKYLSYRELDSLSRALGGWLQGLGLQKGARVAIMMPNVLQYPIAIAAILRAG 97 Query: 3141 ATYVPLDPDYPVQRLAAIIEDSA-------------LSLLLSQTS--------------- 3172 T V ++P Y + L ++DS L +++ T+ Sbjct: 98 YTVVNVNPLYTARELEHQLKDSGAEAIFVLENFACTLQKVVAHTNIKHIVVASMGELLGA 157 Query: 3173 ------------VSQRLPGGRAEQTLYLDQLDLQAQPHDEPDVTIHSDSLAYVIYTSGST 3220 V + +P + Q QA+ VT+ D +A++ YT G+T Sbjct: 158 LKGTLVNLVVRHVKKLVPAWSLPNAITFSQALSQARGKTLQPVTLTHDDIAFLQYTGGTT 217 Query: 3221 GRPKGVGISHRCLMEHGQIAAD----------------FFGLTPQDCMLQFSTLNFDGCI 3264 G KG ++HR L+ + A + F P + + N G Sbjct: 218 GVAKGAVLTHRNLVANVLQAEEWLTPALKAGKPIDQLVFVCALPLYHIFALTVCNMLGTR 277 Query: 3265 EQLFPPLLVGAAVVLRGPELWDSQRLHVELLAHRISVLD-LTTAYWLLLVQ-DFARMGVP 3322 E A+ L P D EL ++++ + T Y LL DFAR+ Sbjct: 278 E---------GALNLLIPNPRDIPGFVKELAKYKVNTFPAVNTLYNALLNNADFARL--- 325 Query: 3323 DYGVLRRVHVGGEAMPPEGIKAWRDAGLAQVELFNTYGPTEATVTASILSCAPYVSGQTV 3382 D+ R GG A+ W+ L + YG +E + AS C T+ Sbjct: 326 DFSGYRCCVGGGMAVQKSVADKWKK--LTGCPIIEGYGLSETSPIASANPC-------TI 376 Query: 3383 LPAQMPIGAPLAGRKLRVLDAELSPLPIGVAGELCIGGELLARGYLNQPGLSAERFVADP 3442 IG PL + +LD + P+P+G GE+ I G + GY +P +A+ D Sbjct: 377 DEYTGTIGLPLPSTEFAILDDDGQPVPLGQPGEIAIRGPQVMPGYWQRPDETAKVMTPD- 435 Query: 3443 LGDGGARLYRTGDLVRWTHAGQLEYLGRIDHQVKIRGFRIEMGEIESIMLAQPEVREAVV 3502 ++TGD+ G + + R + + GF + E+E ++ P V E Sbjct: 436 ------GFFKTGDIGVMDERGYTKIVDRKKDMILVSGFNVYPNEVEGVVAQHPGVLECAC 489 Query: 3503 VAREGVGSLQLVAYVTPQHGRHIETAELRECLVRHLPDYMVPAALVVLPALPLNANGKVD 3562 V + + V + + + A+L + Y P + LP GK+ Sbjct: 490 VGVPDEHTGEAVKLFVVRKDKTLSAAQLMDYCKEQFTGYKKPKYIEFRDELPKTNVGKIL 549 Query: 3563 RKAL 3566 R+ L Sbjct: 550 RREL 553 Score = 70.9 bits (172), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 122/505 (24%), Positives = 188/505 (37%), Gaps = 84/505 (16%) Query: 2052 RVAIHAERSCAFVVAVLATLRVGAAYVPLDPALPAERLHYQLQDSAA----------VLL 2101 RVAI + +A+ A LR G V ++P A L +QL+DS A L Sbjct: 75 RVAIMMPNVLQYPIAIAAILRAGYTVVNVNPLYTARELEHQLKDSGAEAIFVLENFACTL 134 Query: 2102 LSATAPDWAASVPVLPLASLHG-------------VPKRVPYCWP---AVHPGQA----- 2140 A + V + L G V K VP W A+ QA Sbjct: 135 QKVVAHTNIKHIVVASMGELLGALKGTLVNLVVRHVKKLVP-AWSLPNAITFSQALSQAR 193 Query: 2141 --------------AYVIYTSGSTGRPKGVVVSRGALANYVAGVLERLD-----LREQDR 2181 A++ YT G+TG KG V++ N VA VL+ + L+ Sbjct: 194 GKTLQPVTLTHDDIAFLQYTGGTTGVAKGAVLTH---RNLVANVLQAEEWLTPALKAGKP 250 Query: 2182 SMAMVSTVGADLGHTVLFGALCS------GRLLHLIP-PQCSFDPDAMASYMEQHQVDVL 2234 +V L H +C+ G L LIP P+ D + +++V+ Sbjct: 251 IDQLVFVCALPLYHIFAL-TVCNMLGTREGALNLLIPNPR---DIPGFVKELAKYKVNTF 306 Query: 2235 KIVPSHLQALLHAASPASV-LPRSRLVLGGEASRKPLLAHIASLRPQCRVMNHYGPTETT 2293 V + ALL+ A A + R +GG + + +A C ++ YG +ET+ Sbjct: 307 PAVNTLYNALLNNADFARLDFSGYRCCVGGGMAVQKSVADKWKKLTGCPIIEGYGLSETS 366 Query: 2294 VGVLTQEASSALDEADSLPIGQPIAQARAYVLDAELQPVPQGVAGELYLAGHGVARAYQQ 2353 + +DE IG P+ +LD + QPVP G GE+ + G V Y Q Sbjct: 367 P--IASANPCTIDEYTGT-IGLPLPSTEFAILDDDGQPVPLGQPGEIAIRGPQVMPGYWQ 423 Query: 2354 RPAQSAERFVADLLEPGQRMYRSGDRVRQLADGSLEFLGRLDGQIKVRGYRVELREIAAL 2413 RP ++A+ D +++GD G + + R I V G+ V E+ + Sbjct: 424 RPDETAKVMTPD------GFFKTGDIGVMDERGYTKIVDRKKDMILVSGFNVYPNEVEGV 477 Query: 2414 LQSLEAVAQAEVVVHSEPAQPGPDGEEVAPQIIAYLVPMGGQTLDVADLRQQLATRLPDY 2473 + V + V PD E + + V +TL A L + Y Sbjct: 478 VAQHPGVLECACV-------GVPD--EHTGEAVKLFVVRKDKTLSAAQLMDYCKEQFTGY 528 Query: 2474 MMPTALVPLHVMPLTPNGKLDRQAL 2498 P + +P T GK+ R+ L Sbjct: 529 KKPKYIEFRDELPKTNVGKILRREL 553 >gi|300310257|ref|YP_003774349.1| acetyl-coenzyme A synthetase [Herbaspirillum seropedicae SmR1] Length = 556 Score = 90.9 bits (224), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 132/494 (26%), Positives = 207/494 (41%), Gaps = 43/494 (8%) Query: 537 QQLSYGALERRANQLAHRLIRLGAGPEVKVGIAVERSLEMVIGLLGILKAGAAYVPLDPE 596 QQ S+ + A ++A+ L + G P V + R+ E++ +LG L+AGA Y PL Sbjct: 65 QQYSFAQVRSMAARVANLLRQQGIQPGQIVAGMLPRTPELLATVLGTLRAGAVYQPLFTA 124 Query: 597 YPAQRLQYMMQDSGMRLLLTQQHVLPTLPPLAGLPVLA--------LDQLDLDDEA---- 644 + + +++ + SG L++T L +A P + L D+D A Sbjct: 125 FGPKAIEHRLALSGASLIVTNVANRDKLDEIANCPQVCTVRESNDPLRAGDIDFRAAVDA 184 Query: 645 ---HQPPAVRVHGENLAYVIYTSGSTGQPKGVANRHCALRNRLAWMQQAYRLEPHDTVLQ 701 P +R G +L ++ TSG+TG KGV AL+ +M++A L P D Sbjct: 185 QSDDFAPVLR-SGADLMLMMSTSGTTGAAKGVPVPLSALQAFSVYMREAVGLLPQDKFWN 243 Query: 702 KTPFSFDVSV-WEFFWPLMIGARLALAQPGDHRDPARLVEQIQRHAVSTLHFVPSMLQAF 760 + + + PL IG + + + E I+R +++L P+ + Sbjct: 244 MADPGWAYGLYYAIIGPLAIGHGITFNEAA--FTVSGTYETIRRLGITSLAGAPTAYRMM 301 Query: 761 LAHDEIEGCSSLHRL---ICSGEALPVEAQQGVFARLPQVALYNLYGPTEAAIDV-THWT 816 +A E S RL +GE L E + FA V +++ YG TE + V H Sbjct: 302 MAAGEEAAASVKGRLRAVSSAGEPLNAEVVRW-FASALDVPIHDHYGQTELGMVVNNHHA 360 Query: 817 CRADGRSQVP--IGRPISSIRTLVLDGDLNLAPQGVPGELYLGGIGLARGYLGRAGLSAE 874 R VP G + R +VLD + PGEL I +AR L S Sbjct: 361 LR---HEVVPGSAGFAMPGYRVVVLDENHQELGANQPGEL---AIDIARSPL--YWFSGY 412 Query: 875 RFVADPFSADGERLYRTGDLVRWNREGQLDYLGRLDHQVKIRGLRIELGEIEARLLAQPG 934 P A G Y TGD V G + ++GR D + G RI ++E+ LL P Sbjct: 413 WKQDTPAIAHG--YYSTGDNVELEPNGSISFIGRSDDVITSAGYRIGPFDVESALLEHPA 470 Query: 935 VREAVVVARESAGTSRLV-AYVSGTDLVAAT------LRSALTKDLPDYMVPALIEVLEH 987 V + V+ + +V A+V +D A+ L + + L + P IE L+ Sbjct: 471 VADVAVIGLPDPERTEIVKAFVVLSDQFKASDALREQLAQHVKRRLSAHAYPRAIEFLDA 530 Query: 988 LPLNANGKVDRRAL 1001 LP +GK+ R L Sbjct: 531 LPKTPSGKLQRFVL 544 Score = 88.2 bits (217), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 127/529 (24%), Positives = 207/529 (39%), Gaps = 53/529 (10%) Query: 3077 SIQPDAVALISGNRSMSYGQLNTRVNQLAHYLLQRGLQPEARVGVALERSADMVVAVLAI 3136 +I + V+L ++ S+ Q+ + ++A+ L Q+G+QP V L R+ +++ VL Sbjct: 52 NIALEFVSLHGEHQQYSFAQVRSMAARVANLLRQQGIQPGQIVAGMLPRTPELLATVLGT 111 Query: 3137 LKAGATYVPLDPDYPVQRLAAIIEDSALSLLLSQTSVSQRLPG----------GRAEQTL 3186 L+AGA Y PL + + + + S SL+++ + +L + L Sbjct: 112 LRAGAVYQPLFTAFGPKAIEHRLALSGASLIVTNVANRDKLDEIANCPQVCTVRESNDPL 171 Query: 3187 YLDQLDLQ----AQPHDEPDVTIHSDSLAYVIYTSGSTGRPKGVGISHRCLMEHGQIAAD 3242 +D + AQ D V L ++ TSG+TG KGV + L + Sbjct: 172 RAGDIDFRAAVDAQSDDFAPVLRSGADLMLMMSTSGTTGAAKGVPVPLSALQAFSVYMRE 231 Query: 3243 FFGLTPQDCMLQFSTLNFD-GCIEQLFPPLLVGAAVVLRGPELWDSQRLHVELLAHRISV 3301 GL PQD + + G + PL +G + S S+ Sbjct: 232 AVGLLPQDKFWNMADPGWAYGLYYAIIGPLAIGHGITFNEAAFTVSGTYETIRRLGITSL 291 Query: 3302 LDLTTAYWLLLVQDFARMGVPDYGVLRRVHVGGEAMPPEGIKAWRDAGLAQVELFNTYGP 3361 TAY +++ G LR V GE + E ++ W + L V + + YG Sbjct: 292 AGAPTAYRMMMAAGEEAAASVK-GRLRAVSSAGEPLNAEVVR-WFASAL-DVPIHDHYGQ 348 Query: 3362 TEATVTASILSCAPYVSGQTVLPAQMPIGAPLAGRKLRVLDAELSPLPIGVAGELCIGGE 3421 TE + + + V+P P G ++ VLD L GEL I Sbjct: 349 TELGMVVN----NHHALRHEVVPGSAGFAMP--GYRVVVLDENHQELGANQPGELAID-- 400 Query: 3422 LLAR-------GYLNQ--PGLSAERFVADPLGDGGARLYRTGDLVRWTHAGQLEYLGRID 3472 +AR GY Q P ++ Y TGD V G + ++GR D Sbjct: 401 -IARSPLYWFSGYWKQDTPAIAHG-------------YYSTGDNVELEPNGSISFIGRSD 446 Query: 3473 HQVKIRGFRIEMGEIESIMLAQPEVREAVVVAREGVGSLQLVAYVTPQHGRHIETAELRE 3532 + G+RI ++ES +L P V + V+ ++V + + LRE Sbjct: 447 DVITSAGYRIGPFDVESALLEHPAVADVAVIGLPDPERTEIVKAFVVLSDQFKASDALRE 506 Query: 3533 CLVRH----LPDYMVPAALVVLPALPLNANGKVDRKALPEPVYESRTGH 3577 L +H L + P A+ L ALP +GK+ R L + + R GH Sbjct: 507 QLAQHVKRRLSAHAYPRAIEFLDALPKTPSGKLQRFVLRKMEADRRAGH 555 Score = 74.7 bits (182), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 126/496 (25%), Positives = 194/496 (39%), Gaps = 63/496 (12%) Query: 2037 QMAQQMRQRGIGCEDRVAIHAERSCAFVVAVLATLRVGAAYVPLDPALPAERLHYQLQDS 2096 ++A +RQ+GI VA R+ + VL TLR GA Y PL A + + ++L S Sbjct: 78 RVANLLRQQGIQPGQIVAGMLPRTPELLATVLGTLRAGAVYQPLFTAFGPKAIEHRLALS 137 Query: 2097 AAVLLLSATAP----DWAASVPVLPLASLHGVPKRVPYC-------------WPAVHPG- 2138 A L+++ A D A+ P + P R P + G Sbjct: 138 GASLIVTNVANRDKLDEIANCPQVCTVRESNDPLRAGDIDFRAAVDAQSDDFAPVLRSGA 197 Query: 2139 QAAYVIYTSGSTGRPKGVVVSRGALANYVAGVLERLDLREQDRSMAMVSTVGADLGHTVL 2198 ++ TSG+TG KGV V AL + + E + L QD+ M A + + Sbjct: 198 DLMLMMSTSGTTGAAKGVPVPLSALQAFSVYMREAVGLLPQDKFWNMADPGWAYGLYYAI 257 Query: 2199 FGALCSGRLLHLIPPQCSFDPDAMASYMEQHQVDVLKIVPSHLQALLHAASPASVLPRSR 2258 G L G + + +F + + + L P+ + ++ A A+ + R Sbjct: 258 IGPLAIGHGITF--NEAAFTVSGTYETIRRLGITSLAGAPTAYRMMMAAGEEAAASVKGR 315 Query: 2259 LVLGGEASRKPLLAHIASLRPQCR---VMNHYGPTETTVGVLTQEASSALDEADSLPIGQ 2315 L A +PL A + + +HYG TE +G++ + E G Sbjct: 316 LRAVSSAG-EPLNAEVVRWFASALDVPIHDHYGQTE--LGMVVNNHHALRHEVVPGSAGF 372 Query: 2316 PIAQARAYVLDAELQPVPQGVAGELYLAGHGVARA---------YQQRPAQSAERFVADL 2366 + R VLD Q + GEL + +AR+ Q PA + Sbjct: 373 AMPGYRVVVLDENHQELGANQPGELAI---DIARSPLYWFSGYWKQDTPAIA-------- 421 Query: 2367 LEPGQRMYRSGDRVRQLADGSLEFLGRLDGQIKVRGYRVELREIAALLQSLEAVAQAEVV 2426 Y +GD V +GS+ F+GR D I GYR+ ++ + L AVA V+ Sbjct: 422 ----HGYYSTGDNVELEPNGSISFIGRSDDVITSAGYRIGPFDVESALLEHPAVADVAVI 477 Query: 2427 VHSEPAQPGPDGEEVAPQIIAYLVPMGGQTLDVADLRQQLAT----RLPDYMMPTALVPL 2482 P P+ E I+ V + Q LR+QLA RL + P A+ L Sbjct: 478 -----GLPDPERTE----IVKAFVVLSDQFKASDALREQLAQHVKRRLSAHAYPRAIEFL 528 Query: 2483 HVMPLTPNGKLDRQAL 2498 +P TP+GKL R L Sbjct: 529 DALPKTPSGKLQRFVL 544 Database: BlastDatabases/689/689 Posted date: Apr 10, 2011 12:15 AM Number of letters in database: 1,619,870 Number of sequences in database: 4735 Lambda K H 0.321 0.135 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 4735 Number of Hits to DB: 12,050,198 Number of extensions: 542170 Number of successful extensions: 2143 Number of sequences better than 1.0e-08: 11 Number of HSP's gapped: 1902 Number of HSP's successfully gapped: 48 Length of query: 3675 Length of database: 1,619,870 Length adjustment: 104 Effective length of query: 3571 Effective length of database: 1,127,430 Effective search space: 4026052530 Effective search space used: 4026052530 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 140 (58.5 bits)