CC   -----------------------------------------------------------------------
CC
CC   ENZYME nomenclature database
CC
CC   -----------------------------------------------------------------------
CC   Release of 21-Sep-2011.
CC   -----------------------------------------------------------------------
CC
CC   Amos Bairoch and Kristian Axelsen
CC   Swiss Institute of Bioinformatics (SIB)
CC   Centre Medical Universitaire (CMU)
CC   1, rue Michel Servet
CC   1211 Geneva 4
CC   Switzerland
CC
CC   Email: enzyme@isb-sib.ch
CC   Telephone: +41-22-379 50 50
CC   Fax: +41-22-379 58 58
CC
CC   WWW server: http://www.expasy.org/enzyme/
CC
CC   -----------------------------------------------------------------------
CC   This database is copyright from the Swiss Institute of Bioinformatics.
CC   There are  no restrictions  on  its use by any institutions as long as
CC   its content is in no way modified.
CC   -----------------------------------------------------------------------
//
ID   1.1.1.1
DE   Alcohol dehydrogenase.
AN   Aldehyde reductase.
CA   An alcohol + NAD(+) = an aldehyde or ketone + NADH.
CF   Zinc or iron.
CC   -!- Acts on primary or secondary alcohols or hemiacetals.
CC   -!- The animal, but not the yeast, enzyme acts also on cyclic secondary
CC       alcohols.
PR   PROSITE; PDOC00058;
PR   PROSITE; PDOC00059;
PR   PROSITE; PDOC00060;
DR   P07327, ADH1A_HUMAN;  P28469, ADH1A_MACMU;  Q5RBP7, ADH1A_PONAB;
DR   P25405, ADH1A_UROHA;  P00325, ADH1B_HUMAN;  Q5R1W2, ADH1B_PANTR;
DR   P14139, ADH1B_PAPHA;  P25406, ADH1B_UROHA;  P00327, ADH1E_HORSE;
DR   P00326, ADH1G_HUMAN;  O97959, ADH1G_PAPHA;  P00328, ADH1S_HORSE;
DR   P80222, ADH1_ALLMI ;  P30350, ADH1_ANAPL ;  P49645, ADH1_APTAU ;
DR   P06525, ADH1_ARATH ;  P41747, ADH1_ASPFN ;  Q17334, ADH1_CAEEL ;
DR   P43067, ADH1_CANAL ;  P85440, ADH1_CATRO ;  P48814, ADH1_CERCA ;
DR   Q70UN9, ADH1_CERCO ;  P23991, ADH1_CHICK ;  P86883, ADH1_COLLI ;
DR   P19631, ADH1_COTJA ;  P23236, ADH1_DROHY ;  P48586, ADH1_DROMN ;
DR   P09370, ADH1_DROMO ;  P22246, ADH1_DROMT ;  P07161, ADH1_DROMU ;
DR   P12854, ADH1_DRONA ;  P08843, ADH1_EMENI ;  P26325, ADH1_GADCA ;
DR   Q9Z2M2, ADH1_GEOAT ;  Q64413, ADH1_GEOBU ;  Q64415, ADH1_GEOKN ;
DR   P12311, ADH1_GEOSE ;  P05336, ADH1_HORVU ;  P20369, ADH1_KLULA ;
DR   Q07288, ADH1_KLUMA ;  P00333, ADH1_MAIZE ;  P86885, ADH1_MESAU ;
DR   P00329, ADH1_MOUSE ;  P80512, ADH1_NAJNA ;  Q9P6C8, ADH1_NEUCR ;
DR   Q75ZX4, ADH1_ORYSI ;  Q2R8Z5, ADH1_ORYSJ ;  P12886, ADH1_PEA   ;
DR   P14219, ADH1_PENAM ;  P41680, ADH1_PERMA ;  P25141, ADH1_PETHY ;
DR   O00097, ADH1_PICST ;  Q03505, ADH1_RABIT ;  P22797, ADH1_RANPE ;
DR   P06757, ADH1_RAT   ;  P14673, ADH1_SOLTU ;  P80338, ADH1_STRCA ;
DR   P13603, ADH1_TRIRP ;  P00330, ADH1_YEAST ;  Q07264, ADH1_ZEALU ;
DR   P20368, ADH1_ZYMMO ;  O45687, ADH2_CAEEL ;  O94038, ADH2_CANAL ;
DR   P48815, ADH2_CERCA ;  Q70UP5, ADH2_CERCO ;  Q70UP6, ADH2_CERRO ;
DR   P27581, ADH2_DROAR ;  P25720, ADH2_DROBU ;  P23237, ADH2_DROHY ;
DR   P48587, ADH2_DROMN ;  P09369, ADH2_DROMO ;  P07160, ADH2_DROMU ;
DR   P24267, ADH2_DROWH ;  P37686, ADH2_ECOLI ;  P54202, ADH2_EMENI ;
DR   Q24803, ADH2_ENTHI ;  P42327, ADH2_GEOSE ;  P10847, ADH2_HORVU ;
DR   P49383, ADH2_KLULA ;  Q9P4C2, ADH2_KLUMA ;  P04707, ADH2_MAIZE ;
DR   Q4R1E8, ADH2_ORYSI ;  Q0ITW7, ADH2_ORYSJ ;  O13309, ADH2_PICST ;
DR   P28032, ADH2_SOLLC ;  P14674, ADH2_SOLTU ;  P00331, ADH2_YEAST ;
DR   P06758, ADH2_ZYMMO ;  P07754, ADH3_EMENI ;  P42328, ADH3_GEOSE ;
DR   P10848, ADH3_HORVU ;  P49384, ADH3_KLULA ;  P14675, ADH3_SOLTU ;
DR   P07246, ADH3_YEAST ;  P08319, ADH4_HUMAN ;  P49385, ADH4_KLULA ;
DR   Q9QYY9, ADH4_MOUSE ;  Q64563, ADH4_RAT   ;  Q09669, ADH4_SCHPO ;
DR   P80468, ADH4_STRCA ;  A6ZTT5, ADH4_YEAS7 ;  P10127, ADH4_YEAST ;
DR   Q6XQ67, ADH5_SACPS ;  P38113, ADH5_YEAST ;  P28332, ADH6_HUMAN ;
DR   P41681, ADH6_PERMA ;  Q5R7Z8, ADH6_PONAB ;  Q5XI95, ADH6_RAT   ;
DR   P40394, ADH7_HUMAN ;  Q64437, ADH7_MOUSE ;  P41682, ADH7_RAT   ;
DR   P95153, ADHA_MYCTU ;  O31186, ADHA_RHIME ;  Q7U1B9, ADHB_MYCBO ;
DR   P71818, ADHB_MYCTU ;  P33744, ADHE_CLOAB ;  P0A9Q8, ADHE_ECO57 ;
DR   P0A9Q7, ADHE_ECOLI ;  P81600, ADHH_GADMO ;  P72324, ADHI_RHOS4 ;
DR   Q9SK86, ADHL1_ARATH;  Q9SK87, ADHL2_ARATH;  A1L4Y2, ADHL3_ARATH;
DR   Q8VZ49, ADHL4_ARATH;  Q0V7W6, ADHL5_ARATH;  Q8LEB2, ADHL6_ARATH;
DR   Q9FH04, ADHL7_ARATH;  P81601, ADHL_GADMO ;  P39451, ADHP_ECOLI ;
DR   O46649, ADHP_RABIT ;  O46650, ADHQ_RABIT ;  Q96533, ADHX_ARATH ;
DR   Q3ZC42, ADHX_BOVIN ;  Q17335, ADHX_CAEEL ;  Q54TC2, ADHX_DICDI ;
DR   P46415, ADHX_DROME ;  P19854, ADHX_HORSE ;  P11766, ADHX_HUMAN ;
DR   P93629, ADHX_MAIZE ;  P28474, ADHX_MOUSE ;  P80360, ADHX_MYXGL ;
DR   P81431, ADHX_OCTVU ;  A2XAZ3, ADHX_ORYSI ;  Q0DWH1, ADHX_ORYSJ ;
DR   P80572, ADHX_PEA   ;  O19053, ADHX_RABIT ;  P12711, ADHX_RAT   ;
DR   P86884, ADHX_SCYCA ;  P79896, ADHX_SPAAU ;  P80467, ADHX_UROHA ;
DR   Q9NAR7, ADH_BACOL  ;  P14940, ADH_CUPNE  ;  Q00669, ADH_DROAD  ;
DR   P21518, ADH_DROAF  ;  P25139, ADH_DROAM  ;  Q50L96, ADH_DROAN  ;
DR   P48584, ADH_DROBO  ;  Q00670, ADH_DROCR  ;  P22245, ADH_DRODI  ;
DR   Q9NG42, ADH_DROEQ  ;  P28483, ADH_DROER  ;  P48585, ADH_DROFL  ;
DR   P51551, ADH_DROGR  ;  Q09009, ADH_DROGU  ;  P51549, ADH_DROHA  ;
DR   P21898, ADH_DROHE  ;  Q07588, ADH_DROIM  ;  Q9NG40, ADH_DROIN  ;
DR   Q27404, ADH_DROLA  ;  P10807, ADH_DROLE  ;  P07162, ADH_DROMA  ;
DR   Q09010, ADH_DROMD  ;  P00334, ADH_DROME  ;  Q00671, ADH_DROMM  ;
DR   P25721, ADH_DROMY  ;  Q00672, ADH_DRONI  ;  P07159, ADH_DROOR  ;
DR   P84328, ADH_DROPB  ;  P37473, ADH_DROPE  ;  P23361, ADH_DROPI  ;
DR   P23277, ADH_DROPL  ;  Q6LCE4, ADH_DROPS  ;  Q9U8S9, ADH_DROPU  ;
DR   Q9GN94, ADH_DROSE  ;  Q24641, ADH_DROSI  ;  P23278, ADH_DROSL  ;
DR   Q03384, ADH_DROSU  ;  P28484, ADH_DROTE  ;  P51550, ADH_DROTS  ;
DR   B4M8Y0, ADH_DROVI  ;  Q05114, ADH_DROWI  ;  P26719, ADH_DROYA  ;
DR   P17648, ADH_FRAAN  ;  P48977, ADH_MALDO  ;  P81786, ADH_MORSE  ;
DR   O53904, ADH_MYCTU  ;  P25988, ADH_SCAAL  ;  P00332, ADH_SCHPO  ;
DR   Q2FJ31, ADH_STAA3  ;  Q2G0G1, ADH_STAA8  ;  Q2YSX0, ADH_STAAB  ;
DR   Q5HI63, ADH_STAAC  ;  Q99W07, ADH_STAAM  ;  Q7A742, ADH_STAAN  ;
DR   Q6GJ63, ADH_STAAR  ;  Q6GBM4, ADH_STAAS  ;  Q8NXU1, ADH_STAAW  ;
DR   Q5HRD6, ADH_STAEQ  ;  Q8CQ56, ADH_STAES  ;  Q4J781, ADH_SULAC  ;
DR   P39462, ADH_SULSO  ;  P50381, ADH_SULSR  ;  Q96XE0, ADH_SULTO  ;
DR   P51552, ADH_ZAPTU  ;  P32771, FADH_YEAST ;  A7ZIA4, FRMA_ECO24 ;
DR   Q8X5J4, FRMA_ECO57 ;  A7ZX04, FRMA_ECOHS ;  A1A835, FRMA_ECOK1 ;
DR   Q0TKS7, FRMA_ECOL5 ;  Q8FKG1, FRMA_ECOL6 ;  B1J085, FRMA_ECOLC ;
DR   P25437, FRMA_ECOLI ;  B1LIP1, FRMA_ECOSM ;  Q1RFI7, FRMA_ECOUT ;
DR   P44557, FRMA_HAEIN ;  P39450, FRMA_PASPI ;  Q3Z550, FRMA_SHISS ;
DR   P73138, FRMA_SYNY3 ;  P71017, GBSB_BACSU ;  P33010, TERPD_PSESP;
//
ID   1.1.1.2
DE   Alcohol dehydrogenase (NADP(+)).
AN   Aldehyde reductase (NADPH).
CA   An alcohol + NADP(+) = an aldehyde + NADPH.
CF   Zinc.
CC   -!- Some members of this group oxidize only primary alcohols; others act
CC       also on secondary alcohols.
CC   -!- May be identical with EC 1.1.1.19, EC 1.1.1.33 and EC 1.1.1.55.
CC   -!- A-specific with respect to NADPH.
PR   PROSITE; PDOC00061;
DR   Q6AZW2, A1A1A_DANRE;  Q568L5, A1A1B_DANRE;  P35630, ADH1_ENTHI ;
DR   Q24857, ADH3_ENTHI ;  Q04894, ADH6_YEAST ;  P25377, ADH7_YEAST ;
DR   O57380, ADH8_RANPE ;  P0CH36, ADHC1_MYCS2;  P0CH37, ADHC2_MYCS2;
DR   P0A4X1, ADHC_MYCBO ;  P0A4X0, ADHC_MYCTU ;  P25984, ADH_CLOBE  ;
DR   P75214, ADH_MYCPN  ;  P14941, ADH_THEBR  ;  Q3ZCJ2, AK1A1_BOVIN;
DR   Q5ZK84, AK1A1_CHICK;  O70473, AK1A1_CRIGR;  P14550, AK1A1_HUMAN;
DR   Q9JII6, AK1A1_MOUSE;  P50578, AK1A1_PIG  ;  Q5R5D5, AK1A1_PONAB;
DR   P51635, AK1A1_RAT  ;  Q6GMC7, AK1A1_XENLA;  Q28FD1, AK1A1_XENTR;
DR   Q9UUN9, ALD2_SPOSA ;  P27800, ALDX_SPOSA ;
//
ID   1.1.1.3
DE   Homoserine dehydrogenase.
CA   L-homoserine + NAD(P)(+) = L-aspartate 4-semialdehyde + NAD(P)H.
CC   -!- The enzyme from Saccharomyces cerevisiae acts most rapidly with
CC       NAD(+); the Neurospora enzyme with NADP(+).
CC   -!- The enzyme from Escherichia coli is a multifunctional protein, which
CC       also catalyzes the reaction of EC 2.7.2.4.
PR   PROSITE; PDOC00800;
DR   P00561, AK1H_ECOLI ;  P27725, AK1H_SERMA ;  P00562, AK2H_ECOLI ;
DR   Q9SA18, AKH1_ARATH ;  P49079, AKH1_MAIZE ;  O81852, AKH2_ARATH ;
DR   P49080, AKH2_MAIZE ;  P57290, AKH_BUCAI  ;  Q8K9U9, AKH_BUCAP  ;
DR   Q89AR4, AKH_BUCBP  ;  P37142, AKH_DAUCA  ;  P44505, AKH_HAEIN  ;
DR   P19582, DHOM_BACSU ;  P08499, DHOM_CORGL ;  Q5B998, DHOM_EMENI ;
DR   Q9ZL20, DHOM_HELPJ ;  P56429, DHOM_HELPY ;  Q9CGD8, DHOM_LACLA ;
DR   P52985, DHOM_LACLC ;  P37143, DHOM_METGL ;  Q58997, DHOM_METJA ;
DR   P63630, DHOM_MYCBO ;  P46806, DHOM_MYCLE ;  P63629, DHOM_MYCTU ;
DR   P29365, DHOM_PSEAE ;  O94671, DHOM_SCHPO ;  P52986, DHOM_SYNY3 ;
DR   P31116, DHOM_YEAST ;  P37144, DHON_METGL ;
//
ID   1.1.1.4
DE   (R,R)-butanediol dehydrogenase.
AN   (R)-2,3-butanediol dehydrogenase.
AN   (R)-diacetyl reductase.
AN   1-amino-2-propanol dehydrogenase.
AN   1-amino-2-propanol oxidoreductase.
AN   2,3-butanediol dehydrogenase.
AN   Aminopropanol oxidoreductase.
AN   Butylene glycol dehydrogenase.
AN   Butyleneglycol dehydrogenase.
AN   D-(-)-butanediol dehydrogenase.
AN   D-1-amino-2-propanol dehydrogenase.
AN   D-1-amino-2-propanol:NAD(2) oxidoreductase.
AN   D-aminopropanol dehydrogenase.
AN   D-butanediol dehydrogenase.
AN   Diacetyl (acetoin) reductase.
CA   (R,R)-butane-2,3-diol + NAD(+) = (R)-acetoin + NADH.
CC   -!- Also converts diacetyl into acetoin with NADH as reductant.
DR   O34788, BDHA_BACSU ;
//
ID   1.1.1.5
DE   Transferred entry: 1.1.1.303 and 1.1.1.304.
//
ID   1.1.1.6
DE   Glycerol dehydrogenase.
AN   NAD-linked glycerol dehydrogenase.
CA   Glycerol + NAD(+) = glycerone + NADH.
CC   -!- Also acts on 1,2-propanediol.
PR   PROSITE; PDOC00059;
DR   O13702, GLD1_SCHPO ;  P45511, GLDA_CITFR ;  P0A9S6, GLDA_ECOL6 ;
DR   P0A9S5, GLDA_ECOLI ;  P32816, GLDA_GEOSE ;  P50173, GLDA_PSEPU ;
DR   Q9WYQ4, GLDA_THEMA ;
//
ID   1.1.1.7
DE   Propanediol-phosphate dehydrogenase.
CA   Propane-1,2-diol 1-phosphate + NAD(+) = hydroxyacetone phosphate + NADH.
//
ID   1.1.1.8
DE   Glycerol-3-phosphate dehydrogenase (NAD(+)).
AN   Alpha-glycerol phosphate dehydrogenase (NAD).
AN   Alpha-glycerophosphate dehydrogenase (NAD).
AN   Glycerol 1-phosphate dehydrogenase.
AN   Glycerol phosphate dehydrogenase (NAD).
AN   Glycerol-3-phosphate dehydrogenase (NAD).
AN   Glycerophosphate dehydrogenase (NAD).
AN   Hydroglycerophosphate dehydrogenase.
AN   L-alpha-glycerol phosphate dehydrogenase.
AN   L-alpha-glycerophosphate dehydrogenase.
AN   L-glycerol phosphate dehydrogenase.
AN   L-glycerol-3-phosphate dehydrogenase.
AN   L-glycerophosphate dehydrogenase.
AN   NAD-alpha-glycerophosphate dehydrogenase.
AN   NAD-dependent glycerol phosphate dehydrogenase.
AN   NAD-dependent glycerol-3-phosphate dehydrogenase.
AN   NAD-L-glycerol-3-phosphate dehydrogenase.
AN   NAD-linked glycerol 3-phosphate dehydrogenase.
AN   NADH-dihydroxyacetone phosphate reductase.
CA   sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH.
CC   -!- Also acts on propane-1,2-diol phosphate and glycerone sulfate (but
CC       with a much lower affinity).
PR   PROSITE; PDOC00740;
DR   Q5XIZ6, GPD1L_DANRE;  Q8N335, GPD1L_HUMAN;  Q3ULJ0, GPD1L_MOUSE;
DR   Q5R5V3, GPD1L_PONAB;  Q801R8, GPD1L_XENLA;  Q6P824, GPD1L_XENTR;
DR   Q6FN96, GPD1_CANGA ;  Q6ZZF4, GPD1_CYBJA ;  Q6J5J3, GPD1_SACBA ;
DR   P21696, GPD1_SCHPO ;  Q9UVF4, GPD1_YARLI ;  Q00055, GPD1_YEAST ;
DR   Q9HGY2, GPD1_ZYGRO ;  Q6FWJ7, GPD2_CANGA ;  Q6ZYA7, GPD2_CYBJA ;
DR   Q09845, GPD2_SCHPO ;  P41911, GPD2_YEAST ;  Q9HGY1, GPD2_ZYGRO ;
DR   Q9SCX9, GPDA_ARATH ;  Q5EA88, GPDA_BOVIN ;  P52425, GPDA_CUPLA ;
DR   Q27556, GPDA_DROAE ;  Q27567, GPDA_DROEZ ;  O97463, GPDA_DROKA ;
DR   P13706, GPDA_DROME ;  Q27928, GPDA_DROPS ;  P07735, GPDA_DROVI ;
DR   P21695, GPDA_HUMAN ;  Q4QHG4, GPDA_LEIMA ;  P90551, GPDA_LEIME ;
DR   P13707, GPDA_MOUSE ;  Q5RCE0, GPDA_PONAB ;  P08507, GPDA_RABIT ;
DR   O35077, GPDA_RAT   ;  O57656, GPDA_TAKRU ;  P90593, GPDA_TRYBB ;
DR   Q26756, GPDA_TRYBR ;  P34517, GPDH2_CAEEL;  Q759G5, GPD_ASHGO  ;
DR   Q4PNS1, GPD_CANTR  ;  Q7Z8E7, GPD_COLGL  ;  Q7ZA45, GPD_LACTH  ;
DR   Q5G5B9, GPD_MAGO7  ;  Q7ZA43, GPD_PICAN  ;  Q6UGN0, GPD_TRIAT  ;
//
ID   1.1.1.9
DE   D-xylulose reductase.
AN   Xylitol dehydrogenase.
CA   Xylitol + NAD(+) = D-xylulose + NADH.
CC   -!- Also acts as an L-erythrulose reductase.
PR   PROSITE; PDOC00058;
DR   C5FTT1, XYL2_ARTOC ;  A1CFY8, XYL2_ASPCL ;  B0YC65, XYL2_ASPFC ;
DR   Q4WAU7, XYL2_ASPFU ;  A2QY54, XYL2_ASPNC ;  Q5GN51, XYL2_ASPNG ;
DR   Q86ZV0, XYL2_ASPOR ;  Q0CWQ2, XYL2_ASPTN ;  Q5ARL6, XYL2_EMENI ;
DR   A1D9C9, XYL2_NEOFI ;  P22144, XYL2_PICST ;  P83049, XYL2_PIG   ;
DR   Q07993, XYL2_YEAST ;  Q8U7Y1, XYLD_AGRT5 ;  Q59545, XYLD_MORMO ;
DR   Q98D10, XYLD_RHILO ;  Q92MT4, XYLD_RHIME ;
//
ID   1.1.1.10
DE   L-xylulose reductase.
CA   Xylitol + NADP(+) = L-xylulose + NADPH.
DR   Q1JP75, DCXR_BOVIN ;  Q21929, DCXR_CAEEL ;  Q920N9, DCXR_CAVPO ;
DR   Q7Z4W1, DCXR_HUMAN ;  Q91XV4, DCXR_MESAU ;  Q91X52, DCXR_MOUSE ;
DR   Q920P0, DCXR_RAT   ;  Q8NK50, DCXR_TRIRE ;  Q8JIS3, DER_CHICK  ;
//
ID   1.1.1.11
DE   D-arabinitol 4-dehydrogenase.
CA   D-arabinitol + NAD(+) = D-xylulose + NADH.
DR   O52720, DALD_KLEPN ;  P58708, DALD_RALSO ;  P58709, DALD_YERPE ;
//
ID   1.1.1.12
DE   L-arabinitol 4-dehydrogenase.
CA   L-arabinitol + NAD(+) = L-xylulose + NADH.
//
ID   1.1.1.13
DE   L-arabinitol 2-dehydrogenase.
AN   L-arabinitol 2-dehydrogenase (ribulose forming).
CA   L-arabinitol + NAD(+) = L-ribulose + NADH.
//
ID   1.1.1.14
DE   L-iditol 2-dehydrogenase.
AN   Glucitol dehydrogenase.
AN   Polyol dehydrogenase.
AN   Sorbitol dehydrogenase.
CA   L-iditol + NAD(+) = L-sorbose + NADH.
CC   -!- This enzyme is widely distributed and has been described in archaea,
CC       bacteria, yeast, plants and animals.
CC   -!- It acts on a number of sugar alcohols, including (but not limited to)
CC       L-iditol, D-glucitol, D-xylitol, and D-galactitol.
CC   -!- Enzymes from different organisms or tissues display different
CC       substrate specificity.
CC   -!- The enzyme is specific to NAD(+) and can not use NADP(+).
PR   PROSITE; PDOC00058;
DR   P35497, DHSO1_YEAST;  Q07786, DHSO2_YEAST;  Q9Z9U1, DHSO_BACHD ;
DR   Q06004, DHSO_BACSU ;  Q02912, DHSO_BOMMO ;  Q58D31, DHSO_BOVIN ;
DR   Q00796, DHSO_HUMAN ;  Q4R639, DHSO_MACFA ;  Q64442, DHSO_MOUSE ;
DR   Q29318, DHSO_PIG   ;  Q5R5F3, DHSO_PONAB ;  P27867, DHSO_RAT   ;
DR   Q59787, DHSO_RHOSH ;  P36624, DHSO_SCHPO ;  P07846, DHSO_SHEEP ;
//
ID   1.1.1.15
DE   D-iditol 2-dehydrogenase.
CA   D-iditol + NAD(+) = D-sorbose + NADH.
CC   -!- Also converts xylitol into L-xylulose and L-glucitol into L-fructose.
//
ID   1.1.1.16
DE   Galactitol 2-dehydrogenase.
CA   Galactitol + NAD(+) = D-tagatose + NADH.
CC   -!- Also converts other alditols containing an L-threo-configuration
CC       adjacent to a primary alcohol group into the corresponding sugars.
//
ID   1.1.1.17
DE   Mannitol-1-phosphate 5-dehydrogenase.
CA   D-mannitol 1-phosphate + NAD(+) = D-fructose 6-phosphate + NADH.
PR   PROSITE; PDOC00751;
DR   A3N2S7, MTLD_ACTP2 ;  B3H2M6, MTLD_ACTP7 ;  B0BRV5, MTLD_ACTPJ ;
DR   A4SS45, MTLD_AERS4 ;  A6RGF3, MTLD_AJECN ;  B6EN80, MTLD_ALISL ;
DR   Q6UQ76, MTLD_ALTAL ;  B7GJR4, MTLD_ANOFW ;  A1RBC4, MTLD_ARTAT ;
DR   B8H7T9, MTLD_ARTCA ;  A0K258, MTLD_ARTS2 ;  A1C6B4, MTLD_ASPCL ;
DR   B0XS99, MTLD_ASPFC ;  Q4X1A4, MTLD_ASPFU ;  A2QD49, MTLD_ASPNC ;
DR   Q8NJJ1, MTLD_ASPNG ;  Q2U059, MTLD_ASPOR ;  Q0CXS6, MTLD_ASPTN ;
DR   A7Z1E8, MTLD_BACA2 ;  Q9K681, MTLD_BACHD ;  Q65NA1, MTLD_BACLD ;
DR   A8F9Z9, MTLD_BACP2 ;  Q5WDV0, MTLD_BACSK ;  P42957, MTLD_BACSU ;
DR   C0Z8I6, MTLD_BREBN ;  B8D8D5, MTLD_BUCA5 ;  P57634, MTLD_BUCAI ;
DR   Q8K912, MTLD_BUCAP ;  B8D892, MTLD_BUCAT ;  Q89A37, MTLD_BUCBP ;
DR   Q2H2D7, MTLD_CHAGB ;  O65992, MTLD_CLOAB ;  Q1DP56, MTLD_COCIM ;
DR   A7ZTE9, MTLD_ECO24 ;  B7ULF5, MTLD_ECO27 ;  B7MFG0, MTLD_ECO45 ;
DR   B7L723, MTLD_ECO55 ;  Q8XDG9, MTLD_ECO57 ;  B5YW99, MTLD_ECO5E ;
DR   B7NPA3, MTLD_ECO7I ;  B7N242, MTLD_ECO81 ;  B7M3M7, MTLD_ECO8A ;
DR   C4ZXJ1, MTLD_ECOBW ;  B1X8L4, MTLD_ECODH ;  A8A660, MTLD_ECOHS ;
DR   Q8FCB7, MTLD_ECOL6 ;  B1IZJ2, MTLD_ECOLC ;  P09424, MTLD_ECOLI ;
DR   B7NEQ1, MTLD_ECOLU ;  B6I3H6, MTLD_ECOSE ;  B1LK35, MTLD_ECOSM ;
DR   Q5B0F5, MTLD_EMENI ;  P27543, MTLD_ENTFA ;  A7MNE5, MTLD_ENTS8 ;
DR   Q6DB14, MTLD_ERWCT ;  B2VCH7, MTLD_ERWT9 ;  B1YHJ8, MTLD_EXIS2 ;
DR   C4L274, MTLD_EXISA ;  Q5KYK6, MTLD_GEOKA ;  Q45421, MTLD_GEOSE ;
DR   A4IPF0, MTLD_GEOTN ;  B5XMV6, MTLD_KLEP3 ;  A6TFJ4, MTLD_KLEP7 ;
DR   Q9XBM6, MTLD_KLEPN ;  Q033M9, MTLD_LACC3 ;  B3WBT3, MTLD_LACCB ;
DR   Q9CJH1, MTLD_LACLA ;  A2RH97, MTLD_LACLM ;  Q033G3, MTLD_LACLS ;
DR   Q88ZS1, MTLD_LACPL ;  Q1WRQ9, MTLD_LACS1 ;  Q6AHH7, MTLD_LEIXX ;
DR   Q5EMU8, MTLD_MAGO7 ;  Q65VJ3, MTLD_MANSM ;  P55800, MTLD_MYCMS ;
DR   P78008, MTLD_MYCPN ;  Q98PH2, MTLD_MYCPU ;  A1DGY9, MTLD_NEOFI ;
DR   Q7SA44, MTLD_NEUCR ;  Q8EN87, MTLD_OCEIH ;  Q874B3, MTLD_PARBR ;
DR   Q9CLY7, MTLD_PASMU ;  C6DII4, MTLD_PECCP ;  B6HRL5, MTLD_PENCW ;
DR   B6QP49, MTLD_PENMQ ;  Q0U6E8, MTLD_PHANO ;  Q6LKE5, MTLD_PHOPR ;
DR   B2AND4, MTLD_PODAN ;  A1SR48, MTLD_PSYIN ;  B2WME4, MTLD_PYRTR ;
DR   B5EX99, MTLD_SALA4 ;  B5FLG3, MTLD_SALDC ;  B5R5B9, MTLD_SALEP ;
DR   B5RGJ1, MTLD_SALG2 ;  B4T977, MTLD_SALHS ;  B4SX95, MTLD_SALNS ;
DR   Q5PLR3, MTLD_SALPA ;  A9MVI4, MTLD_SALPB ;  B5BHX1, MTLD_SALPK ;
DR   B4TZT8, MTLD_SALSV ;  Q8Z2E0, MTLD_SALTI ;  Q8ZL67, MTLD_SALTY ;
DR   A7F8U1, MTLD_SCLS1 ;  A8G7U3, MTLD_SERP5 ;  B2U5B1, MTLD_SHIB3 ;
DR   Q31V29, MTLD_SHIBS ;  Q83PQ0, MTLD_SHIFL ;  Q3YVW2, MTLD_SHISS ;
DR   Q2NX35, MTLD_SODGM ;  A7X522, MTLD_STAA1 ;  A6U3N9, MTLD_STAA2 ;
DR   Q2FEX4, MTLD_STAA3 ;  Q2FW96, MTLD_STAA8 ;  A5IUU9, MTLD_STAA9 ;
DR   Q2YYE8, MTLD_STAAB ;  Q9RL68, MTLD_STAAC ;  A6QJ00, MTLD_STAAE ;
DR   P63955, MTLD_STAAM ;  P99140, MTLD_STAAN ;  Q6GER8, MTLD_STAAR ;
DR   Q6G7F3, MTLD_STAAS ;  A8YYC5, MTLD_STAAT ;  P63956, MTLD_STAAW ;
DR   B9DM96, MTLD_STACT ;  Q4L9Y4, MTLD_STAHJ ;  Q49ZA6, MTLD_STAS1 ;
DR   Q02418, MTLD_STRMU ;  Q04M75, MTLD_STRP2 ;  B5E7E0, MTLD_STRP4 ;
DR   C1C5D6, MTLD_STRP7 ;  B1I9J3, MTLD_STRPI ;  B8ZLG6, MTLD_STRPJ ;
DR   Q97SH1, MTLD_STRPN ;  B2ILU3, MTLD_STRPS ;  Q8DR31, MTLD_STRR6 ;
DR   C1CCG5, MTLD_STRZJ ;  B0KCW3, MTLD_THEP3 ;  B0K280, MTLD_THEPX ;
DR   Q8RCS0, MTLD_THETN ;  C4L8P4, MTLD_TOLAT ;  A5F155, MTLD_VIBC3 ;
DR   Q9KKQ6, MTLD_VIBCH ;  C3LWV8, MTLD_VIBCM ;  A7MWS7, MTLD_VIBHB ;
DR   Q87SQ3, MTLD_VIBPA ;  Q8DEF5, MTLD_VIBVU ;  Q7MP60, MTLD_VIBVY ;
DR   A1JT46, MTLD_YERE8 ;  A7FP92, MTLD_YERP3 ;  Q1C3J5, MTLD_YERPA ;
DR   B2K7G3, MTLD_YERPB ;  Q8Z9X0, MTLD_YERPE ;  A9R4F6, MTLD_YERPG ;
DR   Q1CD89, MTLD_YERPN ;  A4TGP0, MTLD_YERPP ;  Q663V5, MTLD_YERPS ;
DR   B1JH11, MTLD_YERPY ;
//
ID   1.1.1.18
DE   Inositol 2-dehydrogenase.
AN   Myo-inositol 2-dehydrogenase.
CA   Myo-inositol + NAD(+) = 2,4,6/3,5-pentahydroxycyclohexanone + NADH.
DR   A1R665, IOLG1_ARTAT;  A1T235, IOLG1_MYCVP;  A4FDY3, IOLG1_SACEN;
DR   A1R674, IOLG2_ARTAT;  A1TC97, IOLG2_MYCVP;  A4FID1, IOLG2_SACEN;
DR   A4FIQ1, IOLG3_SACEN;  A4FK61, IOLG4_SACEN;  A0LVX1, IOLG_ACIC1 ;
DR   A5G0Y2, IOLG_ACICJ ;  Q7CV90, IOLG_AGRT5 ;  B8HDD2, IOLG_ARTCA ;
DR   A0JT53, IOLG_ARTS2 ;  C1DLA8, IOLG_AZOVD ;  A7ZAH5, IOLG_BACA2 ;
DR   Q9KAH1, IOLG_BACHD ;  Q65D06, IOLG_BACLD ;  Q5WKY6, IOLG_BACSK ;
DR   P26935, IOLG_BACSU ;  C5BYN4, IOLG_BEUC1 ;  B1YNW1, IOLG_BURA4 ;
DR   Q1BX00, IOLG_BURCA ;  B1K045, IOLG_BURCC ;  A0K6Q3, IOLG_BURCH ;
DR   Q0BG57, IOLG_BURCM ;  A9ABZ7, IOLG_BURM1 ;  Q39H98, IOLG_BURS3 ;
DR   A4JDP6, IOLG_BURVG ;  A4QAF9, IOLG_CORGB ;  Q8NTY7, IOLG_CORGL ;
DR   A9BZG3, IOLG_DELAS ;  B2VJP4, IOLG_ERWT9 ;  A9H5B7, IOLG_GLUDA ;
DR   A6WFC5, IOLG_KINRD ;  B5Y2S5, IOLG_KLEP3 ;  A6THJ2, IOLG_KLEP7 ;
DR   A5YBJ7, IOLG_LACCA ;  Q88S38, IOLG_LACPL ;  Q6AC27, IOLG_LEIXX ;
DR   A4T2N4, IOLG_MYCGI ;  A0R191, IOLG_MYCS2 ;  A1B2N1, IOLG_PARDP ;
DR   Q48GY3, IOLG_PSE14 ;  Q4KDI5, IOLG_PSEF5 ;  C3K9I8, IOLG_PSEFS ;
DR   Q87ZD5, IOLG_PSESM ;  Q4ZRC2, IOLG_PSEU2 ;  Q8XZZ9, IOLG_RALSO ;
DR   A9WKW2, IOLG_RENSM ;  C3MH72, IOLG_RHISN ;  C0ZWI9, IOLG_RHOE4 ;
DR   A3PRX7, IOLG_RHOS1 ;  Q3IX44, IOLG_RHOS4 ;  B9KTD9, IOLG_RHOSK ;
DR   Q0SH07, IOLG_RHOSR ;  Q1AV95, IOLG_RUBXD ;  B5F3F4, IOLG_SALA4 ;
DR   A9N564, IOLG_SALPB ;  Q8ZK57, IOLG_SALTY ;  A8GKW1, IOLG_SERP5 ;
DR   Q82NQ8, IOLG_STRAW ;  Q9X7U5, IOLG_STRCO ;  A1JSK7, IOLG_YERE8 ;
DR   O68965, MI2D_RHIME ;
//
ID   1.1.1.19
DE   Glucuronate reductase.
AN   Aldehyde reductase.
AN   Aldehyde reductase II.
AN   D-glucuronate dehydrogenase.
AN   D-glucuronate reductase.
AN   Glucuronate dehydrogenase.
AN   L-glucuronate reductase.
AN   NADP-L-gulonate dehydrogenase.
AN   TPN-L-gulonate dehydrogenase.
CA   L-gulonate + NADP(+) = D-glucuronate + NADPH.
CC   -!- Also reduces D-galacturonate.
CC   -!- May be identical with EC 1.1.1.2.
//
ID   1.1.1.20
DE   Glucuronolactone reductase.
CA   L-gulono-1,4-lactone + NADP(+) = D-glucurono-3,6-lactone + NADPH.
//
ID   1.1.1.21
DE   Aldehyde reductase.
AN   Aldose reductase.
AN   Polyol dehydrogenase (NADP(+)).
CA   Alditol + NAD(P)(+) = aldose + NAD(P)H.
CC   -!- Wide specificity.
CC   -!- Formerly EC 1.1.1.139.
PR   PROSITE; PDOC00061;
DR   P21300, ALD1_MOUSE ;  O08782, ALD2_CRIGR ;  P45377, ALD2_MOUSE ;
DR   P16116, ALDR_BOVIN ;  Q8SSK6, ALDR_ENCCU ;  P23901, ALDR_HORVU ;
DR   P15121, ALDR_HUMAN ;  P45376, ALDR_MOUSE ;  P80276, ALDR_PIG   ;
DR   P15122, ALDR_RABIT ;  P07943, ALDR_RAT   ;  Q6IMN8, ALRA_DICDI ;
DR   Q54NZ7, ALRB_DICDI ;  Q55FL3, ALRC_DICDI ;  P38715, GRE3_YEAST ;
//
ID   1.1.1.22
DE   UDP-glucose 6-dehydrogenase.
CA   UDP-glucose + 2 NAD(+) + H(2)O = UDP-glucuronate + 2 NADH.
CC   -!- Also acts on UDP-2-deoxyglucose.
DR   O32271, TUAD_BACSU ;  Q47329, UDG5_ECOLX ;  O33952, UDG8_ECOLX ;
DR   Q04872, UDG_ECO11  ;  Q7DBF9, UDG_ECO57  ;  Q8FG45, UDG_ECOL6  ;
DR   P76373, UDG_ECOLI  ;  O86422, UDG_PSEAE  ;  O54068, UDG_RHIME  ;
DR   Q1RKF8, UDG_RICBR  ;  Q92GB1, UDG_RICCN  ;  Q4UK39, UDG_RICFE  ;
DR   O05973, UDG_RICPR  ;  Q68VX0, UDG_RICTY  ;  Q04873, UDG_SALTY  ;
DR   P37791, UDG_SHIFL  ;  P0C0F5, UDG_STRP1  ;  P0DG68, UDG_STRP3  ;
DR   Q5X9A8, UDG_STRP6  ;  Q8NKX0, UDG_STRP8  ;  Q57346, UDG_STRPN  ;
DR   P0DG69, UDG_STRPQ  ;  P0C0F4, UDG_STRPY  ;  Q9LIA8, UGDH1_ARATH;
DR   Q9FM01, UGDH2_ARATH;  P12378, UGDH_BOVIN ;  Q19905, UGDH_CAEEL ;
DR   Q5F3T9, UGDH_CHICK ;  O02373, UGDH_DROME ;  O60701, UGDH_HUMAN ;
DR   O70475, UGDH_MOUSE ;  Q5R7B3, UGDH_PONAB ;  O70199, UGDH_RAT   ;
DR   Q96558, UGDH_SOYBN ;  O34862, YTCA_BACSU ;  P96718, YWQF_BACSU ;
//
ID   1.1.1.23
DE   Histidinol dehydrogenase.
CA   L-histidinol + H(2)O + 2 NAD(+) = L-histidine + 2 NADH.
CC   -!- Also oxidizes L-histidinal.
CC   -!- The Neurospora enzyme also catalyzes the reactions of EC 3.5.4.19 and
CC       EC 3.6.1.31.
PR   PROSITE; PDOC00534;
DR   O74712, HIS2_CANAL ;  O13471, HIS2_KLULA ;  P07685, HIS2_NEUCR ;
DR   P45353, HIS2_PICPA ;  Q12670, HIS2_SACBA ;  P00815, HIS2_YEAST ;
DR   Q7N6I1, HIS8_PHOLL ;  Q3MEV7, HISX1_ANAVT;  Q5WIU9, HISX1_BACSK;
DR   Q47XB8, HISX1_COLP3;  Q46WL2, HISX1_CUPPJ;  Q8YSM8, HISX1_NOSS1;
DR   Q4FNE2, HISX1_PELUB;  Q989E7, HISX1_RHILO;  Q92S26, HISX1_RHIME;
DR   Q3J079, HISX1_RHOS4;  Q5LVV1, HISX1_SILPO;  P73058, HISX1_SYNY3;
DR   Q3M5D3, HISX2_ANAVT;  Q5WDH8, HISX2_BACSK;  Q483H8, HISX2_COLP3;
DR   Q46N53, HISX2_CUPPJ;  Q8YWL4, HISX2_NOSS1;  Q4FMH0, HISX2_PELUB;
DR   Q988P7, HISX2_RHILO;  Q930I4, HISX2_RHIME;  Q3J4H6, HISX2_RHOS4;
DR   Q5LUS2, HISX2_SILPO;  P72946, HISX2_SYNY3;  Q987C6, HISX3_RHILO;
DR   Q5LL27, HISX3_SILPO;  Q6FEC8, HISX_ACIAD ;  Q8UHX1, HISX_AGRT5 ;
DR   O66976, HISX_AQUAE ;  Q9C5U8, HISX_ARATH ;  O30027, HISX_ARCFU ;
DR   Q5P790, HISX_AROAE ;  P18786, HISX_AZOBR ;  Q81T62, HISX_BACAN ;
DR   P62456, HISX_BACC1 ;  Q81G06, HISX_BACCR ;  Q63DX2, HISX_BACCZ ;
DR   Q5LAZ8, HISX_BACFN ;  Q64RE7, HISX_BACFR ;  Q9K6Z2, HISX_BACHD ;
DR   Q6HLE7, HISX_BACHK ;  Q65EF9, HISX_BACLD ;  O34651, HISX_BACSU ;
DR   Q8ABA9, HISX_BACTN ;  Q8G4S9, HISX_BIFLO ;  Q7VQX0, HISX_BLOFL ;
DR   Q492K3, HISX_BLOPB ;  Q7WDY4, HISX_BORBR ;  Q7W2Y4, HISX_BORPA ;
DR   Q7VSZ1, HISX_BORPE ;  P59397, HISX_BRAJA ;  P24226, HISX_BRAOC ;
DR   Q2YPB8, HISX_BRUA2 ;  Q57F99, HISX_BRUAB ;  Q8YF59, HISX_BRUME ;
DR   Q8G2R2, HISX_BRUSU ;  P57201, HISX_BUCAI ;  Q9ZHE6, HISX_BUCAP ;
DR   P59398, HISX_BUCBP ;  Q9RQ88, HISX_BUCDN ;  Q9RQ82, HISX_BUCMH ;
DR   Q9RQ85, HISX_BUCSC ;  Q845V3, HISX_BURM1 ;  Q62GD9, HISX_BURMA ;
DR   Q3JMZ6, HISX_BURP1 ;  Q63Q86, HISX_BURPS ;  Q39K91, HISX_BURS3 ;
DR   Q9PM77, HISX_CAMJE ;  Q5HSJ3, HISX_CAMJR ;  Q3AD53, HISX_CARHZ ;
DR   Q9A5V1, HISX_CAUCR ;  Q3AR25, HISX_CHLCH ;  Q8KEY6, HISX_CHLTE ;
DR   Q7P0F6, HISX_CHRVO ;  Q97KI2, HISX_CLOAB ;  P60858, HISX_CORDI ;
DR   Q8FNZ0, HISX_COREF ;  Q8NNT5, HISX_CORGL ;  Q4JW59, HISX_CORJK ;
DR   Q47AL5, HISX_DECAR ;  Q3Z878, HISX_DEHE1 ;  Q3ZXL7, HISX_DEHSC ;
DR   Q9RSI4, HISX_DEIRA ;  Q313T7, HISX_DESDG ;  Q6ANR3, HISX_DESPS ;
DR   P62457, HISX_DESVH ;  Q8X8T3, HISX_ECO57 ;  Q8FG52, HISX_ECOL6 ;
DR   P06988, HISX_ECOLI ;  Q6D411, HISX_ERWCT ;  Q5KVC6, HISX_GEOKA ;
DR   Q39YP7, HISX_GEOMG ;  P60859, HISX_GEOSL ;  Q7NL02, HISX_GLOVI ;
DR   Q5FS83, HISX_GLUOX ;  Q4QN74, HISX_HAEI8 ;  P44001, HISX_HAEIN ;
DR   Q5V574, HISX_HALMA ;  Q9HPW5, HISX_HALSA ;  Q7VFF5, HISX_HELHP ;
DR   Q8GDP4, HISX_HELMO ;  Q5QWP8, HISX_IDILO ;  Q02136, HISX_LACLA ;
DR   P59399, HISX_LACPL ;  Q5X5W9, HISX_LEGPA ;  Q5ZW87, HISX_LEGPH ;
DR   Q5WX91, HISX_LEGPL ;  Q6AE76, HISX_LEIXX ;  B0S9F2, HISX_LEPBA ;
DR   B0SS41, HISX_LEPBP ;  P62458, HISX_LEPIC ;  Q8F393, HISX_LEPIN ;
DR   Q92E84, HISX_LISIN ;  Q722Y3, HISX_LISMF ;  Q8Y9G1, HISX_LISMO ;
DR   Q65RB1, HISX_MANSM ;  Q8TL41, HISX_METAC ;  Q465R4, HISX_METBF ;
DR   Q606Q2, HISX_METCA ;  Q58851, HISX_METJA ;  Q8TXG3, HISX_METKA ;
DR   Q8PZR8, HISX_METMA ;  P60862, HISX_METMP ;  O26327, HISX_METTH ;
DR   Q2RGV8, HISX_MOOTA ;  P63951, HISX_MYCBO ;  Q9CC57, HISX_MYCLE ;
DR   P60860, HISX_MYCPA ;  P28736, HISX_MYCSM ;  P63950, HISX_MYCTU ;
DR   Q3IQR5, HISX_NATPD ;  Q5F7D8, HISX_NEIG1 ;  Q9JTH9, HISX_NEIMA ;
DR   Q9JYH8, HISX_NEIMB ;  Q82W26, HISX_NITEU ;  Q2YAU5, HISX_NITMU ;
DR   Q3J7H1, HISX_NITOC ;  Q3SW26, HISX_NITWN ;  Q5YYQ0, HISX_NOCFA ;
DR   Q8ESR8, HISX_OCEIH ;  Q5NAY4, HISX_ORYSJ ;  Q9CLM4, HISX_PASMU ;
DR   Q3A133, HISX_PELCD ;  Q3B5E3, HISX_PELLD ;  P62459, HISX_PHOPR ;
DR   Q6KZD1, HISX_PICTO ;  Q6A8L5, HISX_PROAC ;  Q318Q4, HISX_PROM9 ;
DR   Q7VA26, HISX_PROMA ;  Q7V5N9, HISX_PROMM ;  Q7V004, HISX_PROMP ;
DR   Q46J19, HISX_PROMT ;  Q48EC9, HISX_PSE14 ;  Q9HVW9, HISX_PSEAE ;
DR   Q4KI73, HISX_PSEF5 ;  Q3ICF0, HISX_PSEHT ;  Q3KHZ2, HISX_PSEPF ;
DR   P59400, HISX_PSEPK ;  Q87WV5, HISX_PSESM ;  Q4ZNV9, HISX_PSEU2 ;
DR   Q4FQF8, HISX_PSYA2 ;  Q8ZY17, HISX_PYRAE ;  O59626, HISX_PYRFU ;
DR   Q5JFR5, HISX_PYRKO ;  Q8XV79, HISX_RALSO ;  Q7UX39, HISX_RHOBA ;
DR   P60861, HISX_RHOPA ;  Q2RQM7, HISX_RHORT ;  Q57MS3, HISX_SALCH ;
DR   Q8GKZ1, HISX_SALEN ;  Q5PDP3, HISX_SALPA ;  Q8Z5K0, HISX_SALTI ;
DR   P10370, HISX_SALTY ;  Q9P777, HISX_SCHPO ;  Q8EFB1, HISX_SHEON ;
DR   Q323J2, HISX_SHIBS ;  Q32EE9, HISX_SHIDS ;  P59401, HISX_SHIFL ;
DR   Q3Z0G5, HISX_SHISS ;  Q2YZB4, HISX_STAAB ;  Q5HCL9, HISX_STAAC ;
DR   P63952, HISX_STAAM ;  P63953, HISX_STAAN ;  Q6GDC6, HISX_STAAR ;
DR   Q6G5Z7, HISX_STAAS ;  P63954, HISX_STAAW ;  Q5HKN8, HISX_STAEQ ;
DR   Q8CQ95, HISX_STAES ;  Q4A044, HISX_STAS1 ;  Q82AA6, HISX_STRAW ;
DR   P16245, HISX_STRCO ;  Q8DTQ7, HISX_STRMU ;  Q4J8I8, HISX_SULAC ;
DR   Q30TA4, HISX_SULDN ;  O33775, HISX_SULSO ;  Q970Y9, HISX_SULTO ;
DR   Q67KH6, HISX_SYMTH ;  Q5MZ26, HISX_SYNP6 ;  Q7U8K7, HISX_SYNPX ;
DR   Q8DGR2, HISX_THEEB ;  Q47QS9, HISX_THEFY ;  Q9X0D1, HISX_THEMA ;
DR   P62460, HISX_THET2 ;  Q5SKC1, HISX_THET8 ;  Q8R882, HISX_THETN ;
DR   Q31GY9, HISX_THICR ;  Q3SI67, HISX_THIDA ;  Q9L6I1, HISX_THIRO ;
DR   Q9F854, HISX_VIBCH ;  Q5E638, HISX_VIBF1 ;  Q87QL1, HISX_VIBPA ;
DR   Q8D8Q0, HISX_VIBVU ;  Q7MLS6, HISX_VIBVY ;  Q7M8K9, HISX_WOLSU ;
DR   Q8PLG9, HISX_XANAC ;  Q3BUF7, HISX_XANC5 ;  Q4UU40, HISX_XANC8 ;
DR   Q8P9P2, HISX_XANCP ;  Q2P3K3, HISX_XANOM ;  Q5H0L1, HISX_XANOR ;
DR   Q9PBC5, HISX_XYLFA ;  Q87C29, HISX_XYLFT ;  Q8ZFX5, HISX_YERPE ;
DR   Q66C49, HISX_YERPS ;  Q9RH05, HISX_ZYMMO ;
//
ID   1.1.1.24
DE   Quinate dehydrogenase.
AN   Quinate 5-dehydrogenase.
AN   Quinate:NAD oxidoreductase.
AN   Quinate:NAD(+) 5-oxidoreductase.
AN   Quinic dehydrogenase.
CA   Quinate + NAD(+) = 3-dehydroquinate + NADH.
CC   -!- The enzyme is specific for quinate as substrate; phenylpyruvate,
CC       phenylalanine, cinnamate and shikimate will not act as substrates.
CC   -!- NAD(+) cannot be replaced by NADP(+).
DR   Q8FSF0, AROE_COREF ;  A4QB65, AROE_CORGB ;  Q9X5C9, AROE_CORGL ;
DR   P25415, DHQA_EMENI ;  P11635, DHQA_NEUCR ;
//
ID   1.1.1.25
DE   Shikimate dehydrogenase.
AN   5-dehydroshikimate reductase.
AN   5-dehydroshikimic reductase.
AN   Dehydroshikimic reductase.
AN   DHS reductase.
AN   Shikimate 5-dehydrogenase.
AN   Shikimate oxidoreductase.
AN   Shikimate:NADP(+) 5-oxidoreductase.
AN   Shikimate:NADP(+) oxidoreductase.
CA   Shikimate + NADP(+) = 3-dehydroshikimate + NADPH.
CC   -!- NAD(+) cannot replace NADP(+).
CC   -!- In higher organisms, this enzyme forms part of a multienzyme complex
CC       with EC 4.2.1.10.
DR   A5H2Q8, ARO11_LODEL;  B6QWH9, ARO11_PENMQ;  A5H2P4, ARO12_LODEL;
DR   B6QCA7, ARO12_PENMQ;  C0NL63, ARO1_AJECG ;  C6HCG7, ARO1_AJECH ;
DR   A6R8Q8, ARO1_AJECN ;  C5G8R4, ARO1_AJEDR ;  C5JKE6, ARO1_AJEDS ;
DR   C5FQ73, ARO1_ARTOC ;  Q74ZZ1, ARO1_ASHGO ;  A1CP85, ARO1_ASPCL ;
DR   B0XRM8, ARO1_ASPFC ;  B8N4Q9, ARO1_ASPFN ;  Q4WS76, ARO1_ASPFU ;
DR   Q2UCP6, ARO1_ASPOR ;  Q0D0F3, ARO1_ASPTN ;  Q5AME2, ARO1_CANAL ;
DR   B9WFG1, ARO1_CANDC ;  Q6FIV4, ARO1_CANGA ;  C5M1X2, ARO1_CANTT ;
DR   C4Y9D5, ARO1_CLAL4 ;  C5PA86, ARO1_COCP7 ;  A8NMB4, ARO1_COPC7 ;
DR   P0CM23, ARO1_CRYNB ;  P0CM22, ARO1_CRYNJ ;  P07547, ARO1_EMENI ;
DR   Q6CJC4, ARO1_KLULA ;  B0D6H2, ARO1_LACBS ;  C5DN02, ARO1_LACTC ;
DR   A4RD09, ARO1_MAGO7 ;  A8QCB2, ARO1_MALGO ;  C7YZ74, ARO1_NECH7 ;
DR   A1D244, ARO1_NEOFI ;  Q8X071, ARO1_NEUCR ;  C1H8L1, ARO1_PARBA ;
DR   C1FYJ9, ARO1_PARBD ;  C0S433, ARO1_PARBP ;  B6HAA7, ARO1_PENCW ;
DR   Q0V3H0, ARO1_PHANO ;  C4R4R8, ARO1_PICPG ;  A3LSZ2, ARO1_PICST ;
DR   Q12659, ARO1_PNECA ;  B2B223, ARO1_PODAN ;  B6JVD0, ARO1_SCHJY ;
DR   Q9P7R0, ARO1_SCHPO ;  A7F7H0, ARO1_SCLS1 ;  Q5XNP0, ARO1_SCLSC ;
DR   D1ZA70, ARO1_SORMK ;  B8M0U4, ARO1_TALSN ;  Q8J294, ARO1_THACU ;
DR   C4JYG6, ARO1_UNCRE ;  Q4P8F6, ARO1_USTMA ;  C9SE96, ARO1_VERA1 ;
DR   Q6C1X5, ARO1_YARLI ;  B3LGE9, ARO1_YEAS1 ;  C7GIN5, ARO1_YEAS2 ;
DR   A6ZY89, ARO1_YEAS7 ;  C8Z543, ARO1_YEAS8 ;  P08566, ARO1_YEAST ;
DR   C5DVG6, ARO1_ZYGRC ;  P56961, ARODE_CHLMU;  Q9Z6M4, ARODE_CHLPN;
DR   O84375, ARODE_CHLTR;  A1TKF1, AROE_ACIAC ;  Q6FEZ7, AROE_ACIAD ;
DR   B7GVX2, AROE_ACIB3 ;  B7IA68, AROE_ACIB5 ;  B2HZQ2, AROE_ACIBC ;
DR   B0VQB5, AROE_ACIBS ;  A3M9B2, AROE_ACIBT ;  B0V707, AROE_ACIBY ;
DR   A5G270, AROE_ACICJ ;  B9MFP8, AROE_ACIET ;  A1WBZ2, AROE_ACISJ ;
DR   A3N1E3, AROE_ACTP2 ;  B3GY26, AROE_ACTP7 ;  B0BQ79, AROE_ACTPJ ;
DR   A6VL68, AROE_ACTSZ ;  A0KEX8, AROE_AERHH ;  A4ST49, AROE_AERS4 ;
DR   B9JG24, AROE_AGRRK ;  Q8UJC5, AROE_AGRT5 ;  Q0VTD6, AROE_ALCBS ;
DR   Q0A4S2, AROE_ALHEH ;  B6EP29, AROE_ALISL ;  A6TM69, AROE_ALKMQ ;
DR   A8MEE1, AROE_ALKOO ;  B4S253, AROE_ALTMD ;  B8J8W8, AROE_ANAD2 ;
DR   Q2IMC7, AROE_ANADE ;  A7H6S7, AROE_ANADF ;  B4ULJ2, AROE_ANASK ;
DR   B9MKW9, AROE_ANATD ;  Q3M8H2, AROE_ANAVT ;  O67049, AROE_AQUAE ;
DR   O27957, AROE_ARCFU ;  Q5P6J9, AROE_AROAE ;  B8H806, AROE_ARTCA ;
DR   A0K2D5, AROE_ARTS2 ;  A8IFY6, AROE_AZOC5 ;  A1K3B9, AROE_AZOSB ;
DR   C3L5T8, AROE_BACAC ;  A0RIV1, AROE_BACAH ;  B7JNW6, AROE_BACC0 ;
DR   Q730K1, AROE_BACC1 ;  B7IYI7, AROE_BACC2 ;  C1ESM8, AROE_BACC3 ;
DR   B7HCW1, AROE_BACC4 ;  B7HPN3, AROE_BACC7 ;  A7GT28, AROE_BACCN ;
DR   B9IYA1, AROE_BACCQ ;  Q818D0, AROE_BACCR ;  Q634K8, AROE_BACCZ ;
DR   Q9KD93, AROE_BACHD ;  Q6HDI8, AROE_BACHK ;  Q65H34, AROE_BACLD ;
DR   Q5WHI2, AROE_BACSK ;  P54374, AROE_BACSU ;  A9VHW1, AROE_BACWK ;
DR   A1UQU2, AROE_BARBK ;  Q6G5A9, AROE_BARHE ;  Q6G1B5, AROE_BARQU ;
DR   A9IKY5, AROE_BART1 ;  Q7VQB8, AROE_BLOFL ;  Q493H9, AROE_BLOPB ;
DR   Q2KUU3, AROE_BORA1 ;  Q7WF83, AROE_BORBR ;  Q7W3V3, AROE_BORPA ;
DR   A9I1U7, AROE_BORPD ;  Q7VUS1, AROE_BORPE ;  C0ZB07, AROE_BREBN ;
DR   B2S968, AROE_BRUA1 ;  Q2YR04, AROE_BRUA2 ;  Q57AI9, AROE_BRUAB ;
DR   A9M9Q4, AROE_BRUC2 ;  C0RFV7, AROE_BRUMB ;  Q8YE20, AROE_BRUME ;
DR   A5VT27, AROE_BRUO2 ;  B0CJG9, AROE_BRUSI ;  Q8FY21, AROE_BRUSU ;
DR   B8D9R6, AROE_BUCA5 ;  Q44607, AROE_BUCAI ;  P46240, AROE_BUCAP ;
DR   B8D818, AROE_BUCAT ;  P59414, AROE_BUCBP ;  Q057D3, AROE_BUCCC ;
DR   A8MCY4, AROE_CALMQ ;  A4XID4, AROE_CALS8 ;  Q3AEF5, AROE_CARHZ ;
DR   B8GWW0, AROE_CAUCN ;  Q9AC57, AROE_CAUCR ;  B3PGZ3, AROE_CELJU ;
DR   Q3AQX0, AROE_CHLCH ;  B3EEM6, AROE_CHLL2 ;  B3ELA4, AROE_CHLPB ;
DR   A1BED6, AROE_CHLPD ;  Q8KBH8, AROE_CHLTE ;  Q1QTK0, AROE_CHRSD ;
DR   Q7NS40, AROE_CHRVO ;  A8AQH6, AROE_CITK8 ;  A7FWA9, AROE_CLOB1 ;
DR   C3L127, AROE_CLOB6 ;  A6M251, AROE_CLOB8 ;  A5I4X1, AROE_CLOBH ;
DR   C1FSW2, AROE_CLOBJ ;  A7GGC7, AROE_CLOBL ;  B1KX91, AROE_CLOBM ;
DR   Q0TT95, AROE_CLOP1 ;  Q8XMI8, AROE_CLOPE ;  Q0SV31, AROE_CLOPS ;
DR   Q48AV5, AROE_COLP3 ;  B6J4B0, AROE_COXB1 ;  B6J3J2, AROE_COXB2 ;
DR   A9KBC1, AROE_COXBN ;  A9NBH0, AROE_COXBR ;  Q83FD0, AROE_COXBU ;
DR   Q0K6Y5, AROE_CUPNH ;  Q46XB7, AROE_CUPPJ ;  B3R6S4, AROE_CUPTR ;
DR   B1WUG7, AROE_CYAA5 ;  B7KFV3, AROE_CYAP7 ;  Q478U6, AROE_DECAR ;
DR   Q3Z990, AROE_DEHE1 ;  A5FRZ5, AROE_DEHSB ;  Q3ZZN3, AROE_DEHSC ;
DR   C6BUS3, AROE_DESAD ;  Q30VD9, AROE_DESDG ;  Q24UV9, AROE_DESHY ;
DR   A4J3A0, AROE_DESRM ;  B5YE16, AROE_DICT6 ;  B8E257, AROE_DICTD ;
DR   A8LPB8, AROE_DINSH ;  A7ZSH0, AROE_ECO24 ;  B7UK05, AROE_ECO27 ;
DR   B7MC45, AROE_ECO45 ;  B7LHX9, AROE_ECO55 ;  Q8X8F9, AROE_ECO57 ;
DR   B5YT01, AROE_ECO5E ;  B7NLK0, AROE_ECO7I ;  B7N0S2, AROE_ECO81 ;
DR   B7M0Y7, AROE_ECO8A ;  C4ZUD6, AROE_ECOBW ;  B1X6D4, AROE_ECODH ;
DR   A8A586, AROE_ECOHS ;  A1AGH3, AROE_ECOK1 ;  Q0TCI0, AROE_ECOL5 ;
DR   Q8FD18, AROE_ECOL6 ;  B1IQ18, AROE_ECOLC ;  P15770, AROE_ECOLI ;
DR   B7NDQ3, AROE_ECOLU ;  B6I1Z5, AROE_ECOSE ;  B1LGN8, AROE_ECOSM ;
DR   Q1R651, AROE_ECOUT ;  C5BF12, AROE_EDWI9 ;  A4WF90, AROE_ENT38 ;
DR   A7MPE1, AROE_ENTS8 ;  Q6D006, AROE_ERWCT ;  B2VK88, AROE_ERWT9 ;
DR   B1YKR3, AROE_EXIS2 ;  C4L3U2, AROE_EXISA ;  B5EH68, AROE_GEOBB ;
DR   Q39VU8, AROE_GEOMG ;  Q74D29, AROE_GEOSL ;  C6E5S6, AROE_GEOSM ;
DR   C5D4W2, AROE_GEOSW ;  Q5FPK1, AROE_GLUOX ;  Q7VNS2, AROE_HAEDU ;
DR   Q4QMR1, AROE_HAEI8 ;  A5UE78, AROE_HAEIE ;  A5UHE8, AROE_HAEIG ;
DR   P43876, AROE_HAEIN ;  B8F634, AROE_HAEPS ;  Q0I1B7, AROE_HAES1 ;
DR   B0UWV8, AROE_HAES2 ;  Q2SQW5, AROE_HAHCH ;  A1WVW8, AROE_HALHL ;
DR   B9LSZ3, AROE_HALLT ;  Q5V450, AROE_HALMA ;  B8D2C6, AROE_HALOH ;
DR   B0R386, AROE_HALS3 ;  Q9HS68, AROE_HALSA ;  Q18KS0, AROE_HALWD ;
DR   Q17Z34, AROE_HELAH ;  Q7VGS3, AROE_HELHP ;  B6JN89, AROE_HELP2 ;
DR   B5Z8P5, AROE_HELPG ;  Q1CS13, AROE_HELPH ;  Q9ZJX8, AROE_HELPJ ;
DR   P56119, AROE_HELPY ;  A4G8N3, AROE_HERAR ;  Q0C6A6, AROE_HYPNA ;
DR   Q5QXJ3, AROE_IDILO ;  A8A8Z7, AROE_IGNH4 ;  A6T2A5, AROE_JANMA ;
DR   Q28VZ9, AROE_JANSC ;  Q9CES7, AROE_LACLA ;  A2RMH6, AROE_LACLM ;
DR   Q02XB7, AROE_LACLS ;  Q38X88, AROE_LACSS ;  C1D8R7, AROE_LARHH ;
DR   Q5X189, AROE_LEGPA ;  A5IHY1, AROE_LEGPC ;  Q5ZRS2, AROE_LEGPH ;
DR   Q5WT02, AROE_LEGPL ;  Q04QM3, AROE_LEPBJ ;  Q054A8, AROE_LEPBL ;
DR   B1Y4W6, AROE_LEPCP ;  Q72N87, AROE_LEPIC ;  Q8F8C0, AROE_LEPIN ;
DR   Q92EG7, AROE_LISIN ;  Q723F9, AROE_LISMF ;  Q8Y9N5, AROE_LISMO ;
DR   B1HUI4, AROE_LYSSC ;  B9E6Y4, AROE_MACCJ ;  Q2VYH4, AROE_MAGSA ;
DR   A0L3K8, AROE_MAGSM ;  A1TWN6, AROE_MARAV ;  Q0AKD6, AROE_MARMM ;
DR   Q11CM4, AROE_MESSB ;  A6UU64, AROE_META3 ;  Q8THC3, AROE_METAC ;
DR   Q46DZ6, AROE_METBF ;  Q12UJ9, AROE_METBU ;  Q603L1, AROE_METCA ;
DR   Q1GYH7, AROE_METFK ;  Q58484, AROE_METJA ;  Q8TZ24, AROE_METKA ;
DR   A9AB08, AROE_METM6 ;  A6VFM7, AROE_METM7 ;  Q8PXE6, AROE_METMA ;
DR   Q6LYQ2, AROE_METMP ;  A2SKR5, AROE_METPP ;  B1M3B2, AROE_METRJ ;
DR   A5UMF6, AROE_METS3 ;  B8EM72, AROE_METSB ;  Q2NGK8, AROE_METST ;
DR   O26344, AROE_METTH ;  A0B999, AROE_METTP ;  A6UNU0, AROE_METVS ;
DR   B0JPM6, AROE_MICAN ;  Q2RI72, AROE_MOOTA ;  Q3ITN9, AROE_NATPD ;
DR   P95337, AROE_NEICI ;  P95340, AROE_NEIFL ;  Q5F6F7, AROE_NEIG1 ;
DR   P95361, AROE_NEIGO ;  P95368, AROE_NEILA ;  A9M2N2, AROE_NEIM0 ;
DR   P56991, AROE_NEIMA ;  P56992, AROE_NEIMB ;  A1KVS6, AROE_NEIMF ;
DR   P95389, AROE_NEIMU ;  P95400, AROE_NEIPH ;  P95399, AROE_NEIPO ;
DR   Q0AIP9, AROE_NITEC ;  Q82U74, AROE_NITEU ;  Q1QP91, AROE_NITHX ;
DR   A9A233, AROE_NITMS ;  Q2YBM5, AROE_NITMU ;  Q3J818, AROE_NITOC ;
DR   Q3SNB4, AROE_NITWN ;  Q8YVC1, AROE_NOSS1 ;  Q8EPU9, AROE_OCEIH ;
DR   B6JIM2, AROE_OLICO ;  A1B5V3, AROE_PARDP ;  A7HSJ1, AROE_PARL1 ;
DR   P57932, AROE_PASMU ;  C6DFR0, AROE_PECCP ;  B4SD14, AROE_PELPB ;
DR   A1ARJ6, AROE_PELPD ;  Q4FNS5, AROE_PELUB ;  B4RBF7, AROE_PHEZH ;
DR   Q7MYI6, AROE_PHOLL ;  Q6LLK1, AROE_PHOPR ;  B4S9K2, AROE_PROA2 ;
DR   A3PFJ4, AROE_PROM0 ;  A8G7L0, AROE_PROM2 ;  A2BZ92, AROE_PROM5 ;
DR   Q317T6, AROE_PROM9 ;  B4F1M1, AROE_PROMH ;  Q7UZG2, AROE_PROMP ;
DR   A2BTT7, AROE_PROMS ;  A4SDK2, AROE_PROVI ;  Q15ZX4, AROE_PSEA6 ;
DR   A6UX87, AROE_PSEA7 ;  P43904, AROE_PSEAE ;  Q3IDI6, AROE_PSEHT ;
DR   A4XNB9, AROE_PSEMY ;  A4VFI4, AROE_PSEU5 ;  Q4FVE5, AROE_PSYA2 ;
DR   Q1QEG9, AROE_PSYCK ;  A1SR30, AROE_PSYIN ;  Q9V1H7, AROE_PYRAB ;
DR   Q8ZW89, AROE_PYRAE ;  Q8U0A6, AROE_PYRFU ;  A1RVD2, AROE_PYRIL ;
DR   Q5JFT1, AROE_PYRKO ;  B3PVT4, AROE_RHIE6 ;  Q2KE99, AROE_RHIEC ;
DR   Q98DY3, AROE_RHILO ;  Q92TF0, AROE_RHIME ;  C3MB73, AROE_RHISN ;
DR   Q2J0J8, AROE_RHOP2 ;  Q6N1S9, AROE_RHOPA ;  Q20YZ3, AROE_RHOPB ;
DR   Q131U9, AROE_RHOPS ;  B3Q7T8, AROE_RHOPT ;  Q2RN88, AROE_RHORT ;
DR   A3PNT1, AROE_RHOS1 ;  Q3IYG9, AROE_RHOS4 ;  A4WVZ4, AROE_RHOS5 ;
DR   B9KPV7, AROE_RHOSK ;  Q16CZ0, AROE_ROSDO ;  Q1AWA3, AROE_RUBXD ;
DR   A1AW87, AROE_RUTMC ;  Q21PT9, AROE_SACD2 ;  Q57J69, AROE_SALCH ;
DR   B5FIX4, AROE_SALDC ;  B5R1D8, AROE_SALEP ;  B5R7P7, AROE_SALG2 ;
DR   B4TJX2, AROE_SALHS ;  Q5PIS9, AROE_SALPA ;  B5BGU8, AROE_SALPK ;
DR   Q2S0A0, AROE_SALRD ;  B4TXA5, AROE_SALSV ;  Q8Z1W5, AROE_SALTI ;
DR   Q8ZLN1, AROE_SALTY ;  A8GKG0, AROE_SERP5 ;  A1S1K8, AROE_SHEAM ;
DR   B8E3K9, AROE_SHEB2 ;  A3CYL3, AROE_SHEB5 ;  A6WHB9, AROE_SHEB8 ;
DR   A9KUB0, AROE_SHEB9 ;  Q12T95, AROE_SHEDO ;  Q08A18, AROE_SHEFN ;
DR   B0TLD8, AROE_SHEHH ;  Q8EKQ0, AROE_SHEON ;  A8GYI2, AROE_SHEPA ;
DR   A4Y1D5, AROE_SHEPC ;  A0KR69, AROE_SHESA ;  Q0HP98, AROE_SHESM ;
DR   Q0I0R4, AROE_SHESR ;  A1RDZ0, AROE_SHESW ;  B1KD01, AROE_SHEWM ;
DR   B2U2P9, AROE_SHIB3 ;  Q31VZ5, AROE_SHIBS ;  Q32B68, AROE_SHIDS ;
DR   Q0T020, AROE_SHIF8 ;  Q83PZ3, AROE_SHIFL ;  Q3YWX7, AROE_SHISS ;
DR   Q1GCM4, AROE_SILST ;  A6UEF5, AROE_SINMW ;  Q2NQQ8, AROE_SODGM ;
DR   Q1GP77, AROE_SPHAL ;  A7X302, AROE_STAA1 ;  A6U268, AROE_STAA2 ;
DR   Q2FGC8, AROE_STAA3 ;  Q2FXY1, AROE_STAA8 ;  A5ITC3, AROE_STAA9 ;
DR   Q2YT32, AROE_STAAB ;  Q5HFG5, AROE_STAAC ;  A6QHD8, AROE_STAAE ;
DR   P63593, AROE_STAAM ;  P63594, AROE_STAAN ;  Q6GGA5, AROE_STAAR ;
DR   Q6G8X2, AROE_STAAS ;  A8Z4D5, AROE_STAAT ;  Q8NWA1, AROE_STAAW ;
DR   B9DNI9, AROE_STACT ;  Q5HNV1, AROE_STAEQ ;  Q8CP09, AROE_STAES ;
DR   Q4L6U7, AROE_STAHJ ;  Q49Y37, AROE_STAS1 ;  Q82M83, AROE_STRAW ;
DR   B4U4B1, AROE_STREM ;  A8AXZ5, AROE_STRGC ;  B4SMU6, AROE_STRM5 ;
DR   B2FMH7, AROE_STRMK ;  Q8DUW3, AROE_STRMU ;  P63597, AROE_STRP1 ;
DR   Q04JX1, AROE_STRP2 ;  P0CZ76, AROE_STRP3 ;  B5E5N4, AROE_STRP4 ;
DR   Q5XAV7, AROE_STRP6 ;  C1C7X7, AROE_STRP7 ;  Q8P031, AROE_STRP8 ;
DR   Q1JAN3, AROE_STRPB ;  Q1JKT5, AROE_STRPC ;  Q1JFS6, AROE_STRPD ;
DR   Q1J5M4, AROE_STRPF ;  B1ICH7, AROE_STRPI ;  B8ZKM5, AROE_STRPJ ;
DR   Q48S56, AROE_STRPM ;  P63595, AROE_STRPN ;  P0CZ77, AROE_STRPQ ;
DR   B2IQJ4, AROE_STRPS ;  B5XMF0, AROE_STRPZ ;  P63596, AROE_STRR6 ;
DR   A4W235, AROE_STRS2 ;  C0MHD5, AROE_STRS7 ;  A3CNV8, AROE_STRSV ;
DR   A4VVS8, AROE_STRSY ;  Q03LH5, AROE_STRTD ;  B9DV19, AROE_STRU0 ;
DR   C1CEW5, AROE_STRZJ ;  C1CL85, AROE_STRZP ;  C1CQX9, AROE_STRZT ;
DR   Q4JC75, AROE_SULAC ;  C3MZF3, AROE_SULIA ;  C4KIN3, AROE_SULIK ;
DR   C3MRB8, AROE_SULIL ;  C3MXK7, AROE_SULIM ;  C3NG01, AROE_SULIN ;
DR   C3N7H5, AROE_SULIY ;  Q980I8, AROE_SULSO ;  Q96Y95, AROE_SULTO ;
DR   Q67N06, AROE_SYMTH ;  A0LLU7, AROE_SYNFM ;  Q2JRC6, AROE_SYNJA ;
DR   Q2JMQ3, AROE_SYNJB ;  Q0AZJ6, AROE_SYNWW ;  P74591, AROE_SYNY3 ;
DR   Q9HLE4, AROE_THEAC ;  Q8DLA6, AROE_THEEB ;  Q9WYI1, AROE_THEMA ;
DR   B9KBV5, AROE_THENN ;  B1YD57, AROE_THENV ;  A5IK72, AROE_THEP1 ;
DR   B1L9E4, AROE_THESQ ;  Q72JT0, AROE_THET2 ;  Q5SJF8, AROE_THET8 ;
DR   Q8RAG2, AROE_THETN ;  Q978S5, AROE_THEVO ;  B5YJ55, AROE_THEYD ;
DR   Q31JC4, AROE_THICR ;  Q3SFZ9, AROE_THIDA ;  B8GTG2, AROE_THISH ;
DR   C4L7Z1, AROE_TOLAT ;  Q0W4U3, AROE_UNCMA ;  A1WJY8, AROE_VEREI ;
DR   A5CWY3, AROE_VESOH ;  A5F4C3, AROE_VIBC3 ;  Q9KVT3, AROE_VIBCH ;
DR   C3LPC9, AROE_VIBCM ;  Q5E1R6, AROE_VIBF1 ;  B5FCV8, AROE_VIBFM ;
DR   A7N127, AROE_VIBHB ;  Q87KE4, AROE_VIBPA ;  B7VMW2, AROE_VIBSL ;
DR   Q8DDD4, AROE_VIBVU ;  Q7MGL5, AROE_VIBVY ;  Q8PFE9, AROE_XANAC ;
DR   Q3BN06, AROE_XANC5 ;  Q4UPE3, AROE_XANC8 ;  B0RXX4, AROE_XANCB ;
DR   Q8P3W6, AROE_XANCP ;  Q2P8K0, AROE_XANOM ;  B2I7C8, AROE_XYLF2 ;
DR   Q9PFN3, AROE_XYLFA ;  B0U410, AROE_XYLFM ;  Q87BC5, AROE_XYLFT ;
DR   A1JRY4, AROE_YERE8 ;  A7FNJ7, AROE_YERP3 ;  Q1C2Y4, AROE_YERPA ;
DR   B2K4Z9, AROE_YERPB ;  Q8ZJ74, AROE_YERPE ;  A9R934, AROE_YERPG ;
DR   Q1CCY1, AROE_YERPN ;  A4TH28, AROE_YERPP ;  Q664V9, AROE_YERPS ;
DR   B1JJI3, AROE_YERPY ;  Q9SQT8, DHQSD_ARATH;
//
ID   1.1.1.26
DE   Glyoxylate reductase.
AN   Glycolate reductase.
AN   Glyoxylic acid reductase.
AN   NADH-dependent glyoxylate reductase.
CA   Glycolate + NAD(+) = glyoxylate + NADH.
CC   -!- Reduces glyoxylate to glycolate or hydroxypyruvate to D-glycerate.
PR   PROSITE; PDOC00063;
DR   P53839, GOR1_YEAST ;  Q9YAW4, GYAR_AERPE ;  B1L765, GYAR_KORCO ;
DR   Q9UYR1, GYAR_PYRAB ;  Q8U3Y2, GYAR_PYRFU ;  O58320, GYAR_PYRHO ;
DR   Q5JEZ2, GYAR_PYRKO ;  C5A1V0, GYAR_THEGJ ;  Q9C4M5, GYAR_THELI ;
DR   B6YWH0, GYAR_THEON ;  A1RYE4, GYAR_THEPD ;
//
ID   1.1.1.27
DE   L-lactate dehydrogenase.
AN   L-lactic acid dehydrogenase.
AN   L-lactic dehydrogenase.
CA   (S)-lactate + NAD(+) = pyruvate + NADH.
CC   -!- Also oxidizes other (S)-2-hydroxymonocarboxylic acids.
CC   -!- NADP(+) acts, more slowly, with the animal, but not the bacterial,
CC       enzyme.
PR   PROSITE; PDOC00062;
DR   Q81RW4, LDH1_BACAN ;  P62047, LDH1_BACC1 ;  Q81EP4, LDH1_BACCR ;
DR   Q63CN1, LDH1_BACCZ ;  Q6HK31, LDH1_BACHK ;  E8MJ15, LDH1_BIFL2 ;
DR   P59050, LDH1_BIFLO ;  Q97MD1, LDH1_CLOAB ;  Q839C1, LDH1_ENTFA ;
DR   Q5FMB0, LDH1_LACAC ;  P62052, LDH1_LACJO ;  Q01462, LDH1_LACLA ;
DR   P04034, LDH1_LACLC ;  P56512, LDH1_LACPL ;  Q92F65, LDH1_LISIN ;
DR   Q724K3, LDH1_LISMF ;  P33380, LDH1_LISMO ;  A7WXP7, LDH1_STAA1 ;
DR   A6TY25, LDH1_STAA2 ;  Q2FK29, LDH1_STAA3 ;  Q2G218, LDH1_STAA8 ;
DR   A5IPA9, LDH1_STAA9 ;  Q2YV38, LDH1_STAAB ;  Q5HJD7, LDH1_STAAC ;
DR   A6QDL6, LDH1_STAAE ;  P65255, LDH1_STAAM ;  P65256, LDH1_STAAN ;
DR   Q6GK73, LDH1_STAAR ;  Q6GCN4, LDH1_STAAS ;  A8Z0K3, LDH1_STAAT ;
DR   P65257, LDH1_STAAW ;  Q81K80, LDH2_BACAN ;  P62048, LDH2_BACC1 ;
DR   Q816G3, LDH2_BACCR ;  Q632G8, LDH2_BACCZ ;  Q6HC14, LDH2_BACHK ;
DR   E8ME30, LDH2_BIFL2 ;  P0CW93, LDH2_BIFLO ;  Q97DC6, LDH2_CLOAB ;
DR   Q838C9, LDH2_ENTFA ;  Q5FKK7, LDH2_LACAC ;  P62053, LDH2_LACJO ;
DR   Q9CII4, LDH2_LACLA ;  P0C2T6, LDH2_LACLC ;  P0CI34, LDH2_LACLM ;
DR   D8KFT1, LDH2_LACLN ;  P59390, LDH2_LACPL ;  Q92BI0, LDH2_LISIN ;
DR   Q71ZD6, LDH2_LISMF ;  Q8Y6Z6, LDH2_LISMO ;  A7X6Y1, LDH2_STAA1 ;
DR   A6U4Y2, LDH2_STAA2 ;  Q2FDQ7, LDH2_STAA3 ;  Q2G1Y5, LDH2_STAA8 ;
DR   A5IW27, LDH2_STAA9 ;  Q2YWF6, LDH2_STAAB ;  Q5HCV0, LDH2_STAAC ;
DR   A6QK89, LDH2_STAAE ;  P65258, LDH2_STAAM ;  P99119, LDH2_STAAN ;
DR   Q6GDK1, LDH2_STAAR ;  Q6G674, LDH2_STAAS ;  P0C7U6, LDH2_STAAT ;
DR   Q8NUM9, LDH2_STAAW ;  Q81XJ7, LDH3_BACAN ;  P62049, LDH3_BACC1 ;
DR   Q815X8, LDH3_BACCR ;  Q631X2, LDH3_BACCZ ;  Q6HBQ8, LDH3_BACHK ;
DR   Q9CGG8, LDH3_LACLA ;  Q6ZMR3, LDH6A_HUMAN;  Q3T056, LDH6B_BOVIN;
DR   Q9BYZ2, LDH6B_HUMAN;  Q4R816, LDH6B_MACFA;  Q9PW06, LDHA_ALLMI ;
DR   Q9W7M6, LDHA_AMBME ;  A0A1F3, LDHA_BOSMU ;  P19858, LDHA_BOVIN ;
DR   Q98SL2, LDHA_CAICA ;  P69080, LDHA_CHAAC ;  O93541, LDHA_CHAGU ;
DR   P00340, LDHA_CHICK ;  P69081, LDHA_CHIRA ;  Q9PW07, LDHA_COLLI ;
DR   O93401, LDHA_CORNI ;  Q9W7K5, LDHA_CYPCA ;  Q9PVK5, LDHA_DANRE ;
DR   Q9PW61, LDHA_DISEL ;  O93544, LDHA_DISMA ;  O93542, LDHA_ELEMC ;
DR   Q92055, LDHA_FUNHE ;  P69083, LDHA_GILMI ;  P69084, LDHA_GILSE ;
DR   O93540, LDHA_GOBGI ;  O93537, LDHA_HARAN ;  P22988, LDHA_HORVU ;
DR   P00338, LDHA_HUMAN ;  O93545, LDHA_LEPNU ;  Q9BE24, LDHA_MACFA ;
DR   Q9XT87, LDHA_MONDO ;  P06151, LDHA_MOUSE ;  P69085, LDHA_NOTAN ;
DR   O93539, LDHA_NOTCO ;  P69086, LDHA_PAGBO ;  Q5R1W9, LDHA_PANTR ;
DR   O93538, LDHA_PARCR ;  O93543, LDHA_PARMG ;  O93546, LDHA_PATTE ;
DR   Q98SL0, LDHA_PELSJ ;  P00339, LDHA_PIG   ;  Q5R5F0, LDHA_PONAB ;
DR   Q9W7L3, LDHA_PYTRG ;  P13491, LDHA_RABIT ;  P04642, LDHA_RAT   ;
DR   Q9PW58, LDHA_RHIDE ;  Q9P4B6, LDHA_RHIOR ;  Q9W7L5, LDHA_SCEUN ;
DR   P79912, LDHA_SCEWO ;  O13276, LDHA_SPHAG ;  O13277, LDHA_SPHID ;
DR   O13278, LDHA_SPHLU ;  P00341, LDHA_SQUAC ;  Q9PT43, LDHA_TRASC ;
DR   P69082, LDHA_TREBE ;  P42120, LDHA_XENLA ;  Q9PVK4, LDHBA_DANRE;
DR   Q6DGK2, LDHBB_DANRE;  Q9PW05, LDHB_ALLMI ;  P13743, LDHB_ANAPL ;
DR   Q9YGL2, LDHB_ANGRO ;  Q5E9B1, LDHB_BOVIN ;  Q98SL1, LDHB_CAICA ;
DR   P00337, LDHB_CHICK ;  Q9PW04, LDHB_COLLI ;  P20373, LDHB_FUNHE ;
DR   P42122, LDHB_FUNPA ;  P22989, LDHB_HORVU ;  P07195, LDHB_HUMAN ;
DR   Q4R5B6, LDHB_MACFA ;  Q9XT86, LDHB_MONDO ;  P16125, LDHB_MOUSE ;
DR   A5A6N7, LDHB_PANTR ;  Q98SK9, LDHB_PELSJ ;  P00336, LDHB_PIG   ;
DR   Q1EG91, LDHB_POLSE ;  P13490, LDHB_RABIT ;  P42123, LDHB_RAT   ;
DR   Q9P4B5, LDHB_RHIOR ;  Q9W7L4, LDHB_SCEUN ;  P79913, LDHB_SCEWO ;
DR   Q9YI05, LDHB_SQUAC ;  Q9PT42, LDHB_TRASC ;  P42119, LDHB_XENLA ;
DR   Q06176, LDHC_FUNHE ;  P07864, LDHC_HUMAN ;  P00342, LDHC_MOUSE ;
DR   Q9TSX5, LDHC_PIG   ;  P19629, LDHC_RAT   ;  Q29563, LDHC_VULVU ;
DR   P42121, LDHC_XENLA ;  P14561, LDHP_BACPS ;  P20619, LDHX_BACPS ;
DR   B9JTR0, LDH_AGRVS  ;  A7Z152, LDH_BACA2  ;  P10655, LDH_BACCA  ;
DR   Q59244, LDH_BACCL  ;  Q9K5Z8, LDH_BACHD  ;  Q65NP0, LDH_BACLD  ;
DR   P00345, LDH_BACME  ;  A8F9Q8, LDH_BACP2  ;  Q5WE04, LDH_BACSK  ;
DR   P13714, LDH_BACSU  ;  B8DSV5, LDH_BIFA0  ;  Q0SP77, LDH_BORAP  ;
DR   O51114, LDH_BORBU  ;  B7J121, LDH_BORBZ  ;  Q662S5, LDH_BORGA  ;
DR   B2S1S1, LDH_BORHD  ;  A1QYN6, LDH_BORT9  ;  P93052, LDH_BOTBR  ;
DR   Q27888, LDH_CAEEL  ;  B3QX21, LDH_CHLT3  ;  A7FU32, LDH_CLOB1  ;
DR   C3KVF0, LDH_CLOB6  ;  A5I1Z6, LDH_CLOBH  ;  C1FMZ1, LDH_CLOBJ  ;
DR   B1IKX1, LDH_CLOBK  ;  A7GDK3, LDH_CLOBL  ;  B1L1N3, LDH_CLOBM  ;
DR   Q0TUX8, LDH_CLOP1  ;  Q8XP62, LDH_CLOPE  ;  Q0SWR1, LDH_CLOPS  ;
DR   Q892U0, LDH_CLOTE  ;  Q8KQC4, LDH_CLOTH  ;  P62050, LDH_CORDI  ;
DR   Q8FLV6, LDH_COREF  ;  A4QHW5, LDH_CORGB  ;  Q8NLN0, LDH_CORGL  ;
DR   Q4JY42, LDH_CORJK  ;  Q07251, LDH_CUPNH  ;  P50933, LDH_DEIRA  ;
DR   A4J898, LDH_DESRM  ;  P62051, LDH_DESVH  ;  A1VG02, LDH_DESVV  ;
DR   Q95028, LDH_DROME  ;  A7HM89, LDH_FERNB  ;  Q8RED8, LDH_FUSNN  ;
DR   Q5L2S0, LDH_GEOKA  ;  P00344, LDH_GEOSE  ;  B9LZ61, LDH_GEOSF  ;
DR   C5D5V2, LDH_GEOSW  ;  A4IKL5, LDH_GEOTN  ;  Q7NG49, LDH_GLOVI  ;
DR   C5CGP2, LDH_KOSOT  ;  P00343, LDH_LACCA  ;  Q04CN9, LDH_LACDB  ;
DR   B2GBW0, LDH_LACF3  ;  O32765, LDH_LACHE  ;  P56511, LDH_LACPE  ;
DR   Q8GMJ0, LDH_LACRE  ;  Q1WSG2, LDH_LACS1  ;  P50934, LDH_LACSK  ;
DR   Q38V71, LDH_LACSS  ;  B9E9F9, LDH_MACCJ  ;  P29038, LDH_MAIZE  ;
DR   Q6F0L9, LDH_MESFL  ;  Q2RHG3, LDH_MOOTA  ;  Q2SS50, LDH_MYCCT  ;
DR   O52354, LDH_MYCGA  ;  P47698, LDH_MYCGE  ;  P0C0J2, LDH_MYCH2  ;
DR   Q4A8M8, LDH_MYCH7  ;  P0C0J3, LDH_MYCHJ  ;  P0C0J4, LDH_MYCHY  ;
DR   Q6KIP9, LDH_MYCMO  ;  P62054, LDH_MYCMS  ;  Q8EUG3, LDH_MYCPE  ;
DR   P78007, LDH_MYCPN  ;  Q98PG4, LDH_MYCPU  ;  Q8ELF0, LDH_OCEIH  ;
DR   Q59645, LDH_PEDAC  ;  Q03DZ7, LDH_PEDPA  ;  P33571, LDH_PETMA  ;
DR   A9BGZ9, LDH_PETMO  ;  Q7SI97, LDH_PLABA  ;  P84793, LDH_PLABE  ;
DR   P13774, LDH_PLAFA  ;  Q27743, LDH_PLAFD  ;  Q6A9C3, LDH_PROAC  ;
DR   Q2S4R2, LDH_SALRD  ;  Q9P7P7, LDH_SCHPO  ;  Q9EVR0, LDH_SELRU  ;
DR   B9DN51, LDH_STACT  ;  Q5HL31, LDH_STAEQ  ;  Q8CMZ0, LDH_STAES  ;
DR   Q4L941, LDH_STAHJ  ;  Q49YJ3, LDH_STAS1  ;  Q3K1C8, LDH_STRA1  ;
DR   Q8E5N4, LDH_STRA3  ;  Q8DZY3, LDH_STRA5  ;  C0M7H8, LDH_STRE4  ;
DR   Q59828, LDH_STREI  ;  B4U309, LDH_STREM  ;  A8AXK9, LDH_STRGC  ;
DR   P26283, LDH_STRMU  ;  P65259, LDH_STRP1  ;  Q04K99, LDH_STRP2  ;
DR   P0DC18, LDH_STRP3  ;  B5E4V6, LDH_STRP4  ;  Q5XC59, LDH_STRP6  ;
DR   C1C7I6, LDH_STRP7  ;  P65261, LDH_STRP8  ;  Q1JBQ9, LDH_STRPB  ;
DR   Q1JLP1, LDH_STRPC  ;  Q1JGU2, LDH_STRPD  ;  Q1J6L1, LDH_STRPF  ;
DR   A2REG9, LDH_STRPG  ;  B1IC17, LDH_STRPI  ;  B8ZQ84, LDH_STRPJ  ;
DR   Q48TK0, LDH_STRPM  ;  P0A3M9, LDH_STRPN  ;  P0DC19, LDH_STRPQ  ;
DR   B5XLJ8, LDH_STRPZ  ;  P0A3N0, LDH_STRR6  ;  A4W1K6, LDH_STRS2  ;
DR   C0MFB5, LDH_STRS7  ;  A3CN70, LDH_STRSV  ;  A4VVA3, LDH_STRSY  ;
DR   Q5LZ83, LDH_STRT1  ;  Q5M3T6, LDH_STRT2  ;  Q03K30, LDH_STRTD  ;
DR   Q60009, LDH_STRTR  ;  B9DS53, LDH_STRU0  ;  C1CEH8, LDH_STRZJ  ;
DR   C1CKW1, LDH_STRZP  ;  C1CR83, LDH_STRZT  ;  Q2JRH2, LDH_SYNJA  ;
DR   Q2JJQ1, LDH_SYNJB  ;  P13715, LDH_THEAQ  ;  P06150, LDH_THECA  ;
DR   A8F6M1, LDH_THELT  ;  P16115, LDH_THEMA  ;  A5IL75, LDH_THEP1  ;
DR   B0KDA4, LDH_THEP3  ;  B0K226, LDH_THEPX  ;  Q7X5C9, LDH_THESA  ;
DR   B1LAF5, LDH_THESQ  ;  P62055, LDH_THET2  ;  Q5SJA1, LDH_THET8  ;
DR   Q27797, LDH_TOXGO  ;  P62056, LDH_TREDE  ;
//
ID   1.1.1.28
DE   D-lactate dehydrogenase.
AN   D-lactic acid dehydrogenase.
AN   D-lactic dehydrogenase.
CA   (R)-lactate + NAD(+) = pyruvate + NADH.
PR   PROSITE; PDOC00063;
DR   P06149, DLD_ECOLI  ;  Q54UF7, LDHD_DICDI ;  P52643, LDHD_ECOLI ;
DR   P45295, LDHD_HAEIN ;  P26297, LDHD_LACDA ;  P30901, LDHD_LACHE ;
DR   P26298, LDHD_LACPE ;  Q88VJ2, LDHD_LACPL ;  P51011, LDHD_LEUMC ;
DR   Q59642, LDHD_PEDAC ;  Q5HD29, LDHD_STAAC ;  P63940, LDHD_STAAM ;
DR   P99116, LDHD_STAAN ;  Q6GDS2, LDHD_STAAR ;  Q6G6F1, LDHD_STAAS ;
DR   P72357, LDHD_STAAU ;  Q8NUT2, LDHD_STAAW ;  Q5HLA0, LDHD_STAEQ ;
DR   Q8CN22, LDHD_STAES ;  Q8E6A9, LDHD_STRA3 ;  Q8E0N5, LDHD_STRA5 ;
DR   Q99ZM2, LDHD_STRP1 ;  O83080, LDHD_TREPA ;
//
ID   1.1.1.29
DE   Glycerate dehydrogenase.
AN   Hydroxypyruvate dehydrogenase.
AN   Hydroxypyruvate reductase.
CA   (R)-glycerate + NAD(+) = hydroxypyruvate + NADH.
PR   PROSITE; PDOC00063;
DR   P13443, DHGY_CUCSA ;  P36234, DHGY_HYPME ;  Q59516, DHGY_METEA ;
//
ID   1.1.1.30
DE   3-hydroxybutyrate dehydrogenase.
AN   D-beta-hydroxybutyrate dehydrogenase.
CA   (R)-3-hydroxybutanoate + NAD(+) = acetoacetate + NADH.
CC   -!- Also oxidizes other 3-hydroxymonocarboxylic acids.
PR   PROSITE; PDOC00060;
DR   Q3T046, BDH2_BOVIN ;  Q561X9, BDH2_DANRE ;  Q9BUT1, BDH2_HUMAN ;
DR   Q8JZV9, BDH2_MOUSE ;  C1C4R8, BDH2_RANCA ;  D4A1J4, BDH2_RAT   ;
DR   Q3KPT7, BDH2_XENLA ;  Q9X6U2, BDHA_CUPNH ;  O86034, BDHA_RHIME ;
DR   Q02337, BDH_BOVIN  ;  Q5ZJZ5, BDH_CHICK  ;  Q02338, BDH_HUMAN  ;
DR   P86198, BDH_MESAU  ;  Q80XN0, BDH_MOUSE  ;  P29147, BDH_RAT    ;
//
ID   1.1.1.31
DE   3-hydroxyisobutyrate dehydrogenase.
CA   3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH.
PR   PROSITE; PDOC00697;
DR   Q9SUC0, 3HIDH_ARATH;  Q2HJD7, 3HIDH_BOVIN;  Q9XTI0, 3HIDH_CAEEL;
DR   Q54CX6, 3HIDH_DICDI;  Q9V8M5, 3HIDH_DROME;  P31937, 3HIDH_HUMAN;
DR   P86199, 3HIDH_MESAU;  Q99L13, 3HIDH_MOUSE;  Q5R5E7, 3HIDH_PONAB;
DR   P32185, 3HIDH_RABIT;  P29266, 3HIDH_RAT  ;  P63936, MMSB_MYCBO ;
DR   P63935, MMSB_MYCTU ;  P28811, MMSB_PSEAE ;
//
ID   1.1.1.32
DE   Mevaldate reductase.
CA   (R)-mevalonate + NAD(+) = mevaldate + NADH.
//
ID   1.1.1.33
DE   Mevaldate reductase (NADPH).
CA   (R)-mevalonate + NADP(+) = mevaldate + NADPH.
CC   -!- May be identical with EC 1.1.1.2.
//
ID   1.1.1.34
DE   Hydroxymethylglutaryl-CoA reductase (NADPH).
AN   3-hydroxy-3-methylglutaryl-coenzyme A reductase.
AN   HMG-CoA reductase.
CA   (R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA +
CA   2 NADPH.
CC   -!- The enzyme is inactivated by EC 2.7.11.31 and reactivated by
CC       EC 3.1.3.47.
PR   PROSITE; PDOC00064;
DR   P14891, HMDH1_ARATH;  P34135, HMDH1_DICDI;  O64966, HMDH1_GOSHI;
DR   P29057, HMDH1_HEVBR;  A2X8W3, HMDH1_ORYSI;  Q0DY59, HMDH1_ORYSJ;
DR   P48020, HMDH1_SOLTU;  P12683, HMDH1_YEAST;  P43256, HMDH2_ARATH;
DR   Q9XEL8, HMDH2_CAPAN;  P34136, HMDH2_DICDI;  O64967, HMDH2_GOSHI;
DR   P29058, HMDH2_HEVBR;  P48022, HMDH2_SOLLC;  Q41437, HMDH2_SOLTU;
DR   P12684, HMDH2_YEAST;  Q00583, HMDH3_HEVBR;  Q9XHL5, HMDH3_ORYSJ;
DR   Q41438, HMDH3_SOLTU;  Q9YAS4, HMDH_AERPE ;  O76819, HMDH_AGRIP ;
DR   O28538, HMDH_ARCFU ;  Q9Y7D2, HMDH_ASPTE ;  Q0C8L9, HMDH_ASPTN ;
DR   P54960, HMDH_BLAGE ;  P48021, HMDH_CAMAC ;  Q03163, HMDH_CATRO ;
DR   P00347, HMDH_CRIGR ;  O74164, HMDH_CYBJA ;  P14773, HMDH_DROME ;
DR   Q12577, HMDH_GIBFU ;  Q59468, HMDH_HALVD ;  P04035, HMDH_HUMAN ;
DR   O24594, HMDH_MAIZE ;  P09610, HMDH_MESAU ;  Q58116, HMDH_METJA ;
DR   O26662, HMDH_METTH ;  Q01237, HMDH_MOUSE ;  Q01559, HMDH_NICSY ;
DR   Q12649, HMDH_PHYBL ;  Q1W675, HMDH_PIG   ;  Q5R6N3, HMDH_PONAB ;
DR   Q9V1R3, HMDH_PYRAB ;  O59469, HMDH_PYRHO ;  Q29512, HMDH_RABIT ;
DR   P51639, HMDH_RAT   ;  P16237, HMDH_SCHMA ;  Q10283, HMDH_SCHPO ;
DR   P16393, HMDH_STRPU ;  O08424, HMDH_SULSO ;  P20715, HMDH_XENLA ;
//
ID   1.1.1.35
DE   3-hydroxyacyl-CoA dehydrogenase.
AN   Beta-hydroxyacyl dehydrogenase.
AN   Beta-keto-reductase.
CA   (S)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + NADH.
CC   -!- Also oxidizes S-3-hydroxyacyl-N-acylthioethanolamine and S-3-
CC       hydroxyacylhydrolipoate.
CC   -!- Some enzymes act, more slowly, with NADP(+).
CC   -!- Broad specificity to acyl chain-length (cf. EC 1.1.1.211).
PR   PROSITE; PDOC00060;
PR   PROSITE; PDOC00065;
DR   Q9ZPI6, AIM1_ARATH ;  P55100, ECHP_CAVPO ;  Q6NYL3, ECHP_DANRE ;
DR   Q08426, ECHP_HUMAN ;  Q9DBM2, ECHP_MOUSE ;  Q5R5M8, ECHP_PONAB ;
DR   P07896, ECHP_RAT   ;  Q4UL32, FAD3_RICFE ;  Q9ZCZ1, FAD3_RICPR ;
DR   Q68WH7, FAD3_RICTY ;  Q6FF68, FADB_ACIAD ;  B7H1I0, FADB_ACIB3 ;
DR   B7I3P1, FADB_ACIB5 ;  B2I2J9, FADB_ACIBC ;  B0VLX4, FADB_ACIBS ;
DR   B0VE45, FADB_ACIBY ;  A0KEL1, FADB_AERHH ;  A4STF2, FADB_AERS4 ;
DR   B6EGU2, FADB_ALISL ;  A8ACZ4, FADB_CITK8 ;  Q489W3, FADB_COLP3 ;
DR   A7ZU51, FADB_ECO24 ;  B7UNH4, FADB_ECO27 ;  B7MHD1, FADB_ECO45 ;
DR   B7L9A7, FADB_ECO55 ;  Q8X8I2, FADB_ECO57 ;  B5YY93, FADB_ECO5E ;
DR   B7NV20, FADB_ECO7I ;  B7N2F2, FADB_ECO81 ;  B7M649, FADB_ECO8A ;
DR   C5A020, FADB_ECOBW ;  B1XAK8, FADB_ECODH ;  A8A6V1, FADB_ECOHS ;
DR   Q0TAL0, FADB_ECOL5 ;  Q8FBI2, FADB_ECOL6 ;  B1IW61, FADB_ECOLC ;
DR   P21177, FADB_ECOLI ;  B7NFE7, FADB_ECOLU ;  B6I4I6, FADB_ECOSE ;
DR   B1LM32, FADB_ECOSM ;  Q1R466, FADB_ECOUT ;  A4WFX4, FADB_ENT38 ;
DR   Q9F0Y7, FADB_ENTCL ;  A7MQP0, FADB_ENTS8 ;  Q6DAP5, FADB_ERWCT ;
DR   B7LTY9, FADB_ESCF3 ;  Q5QXH7, FADB_IDILO ;  B5XYH0, FADB_KLEP3 ;
DR   A6TGM4, FADB_KLEP7 ;  Q7MZ92, FADB_PHOLL ;  Q6LW06, FADB_PHOPR ;
DR   Q48GW3, FADB_PSE14 ;  A6V382, FADB_PSEA7 ;  B7UYR6, FADB_PSEA8 ;
DR   Q02PH8, FADB_PSEAB ;  Q9HZJ2, FADB_PSEAE ;  Q1I7D4, FADB_PSEE4 ;
DR   Q4KFC4, FADB_PSEF5 ;  P28793, FADB_PSEFR ;  C3K613, FADB_PSEFS ;
DR   A4XSM8, FADB_PSEMY ;  Q93Q12, FADB_PSEOL ;  A5W6H0, FADB_PSEP1 ;
DR   Q3K9D8, FADB_PSEPF ;  B0KH74, FADB_PSEPG ;  Q88L02, FADB_PSEPK ;
DR   Q9AHY3, FADB_PSEPU ;  B1J5A5, FADB_PSEPW ;  Q87ZB2, FADB_PSESM ;
DR   Q4ZRA0, FADB_PSEU2 ;  A4VKA3, FADB_PSEU5 ;  Q4FQC6, FADB_PSYA2 ;
DR   Q1Q8J9, FADB_PSYCK ;  A5WH99, FADB_PSYWF ;  B5EZW0, FADB_SALA4 ;
DR   Q57HM6, FADB_SALCH ;  B5QW85, FADB_SALEP ;  B5RFL6, FADB_SALG2 ;
DR   B4SZ85, FADB_SALNS ;  Q5PKQ2, FADB_SALPA ;  A9MYB0, FADB_SALPB ;
DR   B5BIZ0, FADB_SALPK ;  B4TNZ1, FADB_SALSV ;  Q8Z3C6, FADB_SALTI ;
DR   Q9L6L5, FADB_SALTY ;  A8G8D1, FADB_SERP5 ;  A1S1I8, FADB_SHEAM ;
DR   B8E3R3, FADB_SHEB2 ;  A3CYJ4, FADB_SHEB5 ;  A6WHA0, FADB_SHEB8 ;
DR   A9KU91, FADB_SHEB9 ;  Q08A39, FADB_SHEFN ;  B0TLB9, FADB_SHEHH ;
DR   A3Q8U4, FADB_SHELP ;  Q8EKR9, FADB_SHEON ;  A8GYG0, FADB_SHEPA ;
DR   A4Y1B6, FADB_SHEPC ;  B8CH91, FADB_SHEPW ;  A0KR50, FADB_SHESA ;
DR   A8FP63, FADB_SHESH ;  Q0HPB7, FADB_SHESM ;  Q0I0T3, FADB_SHESR ;
DR   A1RDW6, FADB_SHESW ;  B1KCZ3, FADB_SHEWM ;  B2TVJ5, FADB_SHIB3 ;
DR   Q32A21, FADB_SHIDS ;  Q0SZ36, FADB_SHIF8 ;  Q83PG1, FADB_SHIFL ;
DR   Q3YVC1, FADB_SHISS ;  A5F465, FADB_VIBC3 ;  Q9KNI1, FADB_VIBCH ;
DR   C3LSI3, FADB_VIBCM ;  Q5E8X6, FADB_VIBF1 ;  B5FEW8, FADB_VIBFM ;
DR   A7N1D2, FADB_VIBHB ;  Q87TN9, FADB_VIBPA ;  B7VGL4, FADB_VIBSL ;
DR   Q8DDK6, FADB_VIBVU ;  Q7MQH9, FADB_VIBVY ;  A1JIG4, FADB_YERE8 ;
DR   A7FDF2, FADB_YERP3 ;  Q1C2C4, FADB_YERPA ;  B2K0Z6, FADB_YERPB ;
DR   Q8ZAN0, FADB_YERPE ;  A9R754, FADB_YERPG ;  Q1CN99, FADB_YERPN ;
DR   A4TR27, FADB_YERPP ;  Q66FR8, FADB_YERPS ;  B1JP63, FADB_YERPY ;
DR   A8ADP2, FADJ_CITK8 ;  A7ZPF8, FADJ_ECO24 ;  B7UFZ8, FADJ_ECO27 ;
DR   B7MGV7, FADJ_ECO45 ;  B7LBJ5, FADJ_ECO55 ;  Q8XCP2, FADJ_ECO57 ;
DR   B5YXY4, FADJ_ECO5E ;  B7NP24, FADJ_ECO7I ;  B7MY16, FADJ_ECO81 ;
DR   B7M6M2, FADJ_ECO8A ;  C4ZVN2, FADJ_ECOBW ;  B1X9L4, FADJ_ECODH ;
DR   A8A2L0, FADJ_ECOHS ;  A1ADI8, FADJ_ECOK1 ;  Q0TFA6, FADJ_ECOL5 ;
DR   Q8FFG4, FADJ_ECOL6 ;  B1IXA5, FADJ_ECOLC ;  P77399, FADJ_ECOLI ;
DR   B7N5V2, FADJ_ECOLU ;  B6I6Q4, FADJ_ECOSE ;  B1LME7, FADJ_ECOSM ;
DR   Q1R972, FADJ_ECOUT ;  A4WCW6, FADJ_ENT38 ;  A7MH81, FADJ_ENTS8 ;
DR   Q6D2L7, FADJ_ERWCT ;  B7LLD0, FADJ_ESCF3 ;  Q5QXM1, FADJ_IDILO ;
DR   B5XVW2, FADJ_KLEP3 ;  A6TC19, FADJ_KLEP7 ;  C6DAL7, FADJ_PECCP ;
DR   Q7N288, FADJ_PHOLL ;  Q6LTK3, FADJ_PHOPR ;  B5EZR9, FADJ_SALA4 ;
DR   Q57LW6, FADJ_SALCH ;  B5FPN1, FADJ_SALDC ;  B5R3R9, FADJ_SALEP ;
DR   B5RCL3, FADJ_SALG2 ;  B4TCA8, FADJ_SALHS ;  B4SZR0, FADJ_SALNS ;
DR   Q5PCX6, FADJ_SALPA ;  A9N453, FADJ_SALPB ;  B5BBA1, FADJ_SALPK ;
DR   B4TQC2, FADJ_SALSV ;  Q8Z4Z0, FADJ_SALTI ;  Q8ZNA7, FADJ_SALTY ;
DR   A8GH86, FADJ_SERP5 ;  A1S7L6, FADJ_SHEAM ;  A3D684, FADJ_SHEB5 ;
DR   A6WQ25, FADJ_SHEB8 ;  Q07ZP8, FADJ_SHEFN ;  B0TL21, FADJ_SHEHH ;
DR   A3QFP3, FADJ_SHELP ;  Q8ECP7, FADJ_SHEON ;  A4Y897, FADJ_SHEPC ;
DR   A0KV76, FADJ_SHESA ;  Q0HKD1, FADJ_SHESM ;  Q0HWN3, FADJ_SHESR ;
DR   A1RI92, FADJ_SHESW ;  B2TWV4, FADJ_SHIB3 ;  Q31YB7, FADJ_SHIBS ;
DR   Q32DJ4, FADJ_SHIDS ;  Q0T2E6, FADJ_SHIF8 ;  Q83QQ0, FADJ_SHIFL ;
DR   Q3YZM2, FADJ_SHISS ;  A5F2P2, FADJ_VIBC3 ;  Q9KT58, FADJ_VIBCH ;
DR   Q5E3U1, FADJ_VIBF1 ;  A7MS61, FADJ_VIBHB ;  Q87MM3, FADJ_VIBPA ;
DR   Q8DB47, FADJ_VIBVU ;  Q7MIS5, FADJ_VIBVY ;  A1JK30, FADJ_YERE8 ;
DR   A7FGK1, FADJ_YERP3 ;  Q1C660, FADJ_YERPA ;  Q8ZD45, FADJ_YERPE ;
DR   Q1CHK2, FADJ_YERPN ;  A4TM82, FADJ_YERPP ;  Q668V1, FADJ_YERPS ;
DR   O32178, FADN_BACSU ;  O02691, HCD2_BOVIN ;  O18404, HCD2_DROME ;
DR   Q99714, HCD2_HUMAN ;  O08756, HCD2_MOUSE ;  O70351, HCD2_RAT   ;
DR   P34439, HCDH1_CAEEL;  P41938, HCDH2_CAEEL;  P83589, HCDH_DEIRA ;
DR   Q16836, HCDH_HUMAN ;  Q61425, HCDH_MOUSE ;  P00348, HCDH_PIG   ;
DR   Q9WVK7, HCDH_RAT   ;  Q9NKW1, MFEA_DICDI ;  Q9ZPI5, MFP2_ARATH ;
DR   O49809, MFPA_BRANA ;  Q39659, MFPA_CUCSA ;  Q8W1L6, MFP_ORYSJ  ;
//
ID   1.1.1.36
DE   Acetoacetyl-CoA reductase.
CA   (R)-3-hydroxyacyl-CoA + NADP(+) = 3-oxoacyl-CoA + NADPH.
PR   PROSITE; PDOC00060;
DR   P50203, PHAB_ACISR ;  P50204, PHAB_PARDE ;  P45375, PHBB_ALLVD ;
DR   P14697, PHBB_CUPNH ;  P50205, PHBB_RHIME ;  P23238, PHBB_ZOORA ;
//
ID   1.1.1.37
DE   Malate dehydrogenase.
AN   Malic dehydrogenase.
CA   (S)-malate + NAD(+) = oxaloacetate + NADH.
CC   -!- Also oxidizes some other 2-hydroxydicarboxylic acids.
PR   PROSITE; PDOC00066;
DR   Q2IIC2, MDH1_ANADE ;  O67655, MDH1_AQUAE ;  Q2T7J2, MDH1_BURTA ;
DR   A4JKE6, MDH1_BURVG ;  Q21XH1, MDH1_RHOFD ;  Q21CW7, MDH1_RHOPB ;
DR   Q2IK16, MDH2_ANADE ;  O67581, MDH2_AQUAE ;  Q2T4T8, MDH2_BURTA ;
DR   A4JM71, MDH2_BURVG ;  Q21VT3, MDH2_RHOFD ;  Q20XN0, MDH2_RHOPB ;
DR   Q54GE6, MDHA_DICDI ;  Q54D04, MDHB_DICDI ;  P93819, MDHC1_ARATH;
DR   P57106, MDHC2_ARATH;  Q9SML8, MDHC_BETVU ;  Q3T145, MDHC_BOVIN ;
DR   P83778, MDHC_CANAL ;  Q5ZME2, MDHC_CHICK ;  Q54VM2, MDHC_DICDI ;
DR   Q04820, MDHC_ECHGR ;  Q7YRU4, MDHC_FELCA ;  P40925, MDHC_HUMAN ;
DR   Q08062, MDHC_MAIZE ;  O48905, MDHC_MEDSA ;  O24047, MDHC_MESCR ;
DR   P14152, MDHC_MOUSE ;  Q7XDC8, MDHC_ORYSJ ;  P11708, MDHC_PIG   ;
DR   O88989, MDHC_RAT   ;  Q6PAB3, MDHC_XENLA ;  Q6DIY9, MDHC_XENTR ;
DR   P22133, MDHC_YEAST ;  Q9ZP05, MDHG1_ARATH;  Q43743, MDHG1_BRANA;
DR   O82399, MDHG2_ARATH;  Q9XFW3, MDHG2_BRANA;  P19446, MDHG_CITLA ;
DR   P46488, MDHG_CUCSA ;  Q42972, MDHG_ORYSJ ;  P37228, MDHG_SOYBN ;
DR   Q9ZP06, MDHM1_ARATH;  Q9LKA3, MDHM2_ARATH;  Q32LG3, MDHM_BOVIN ;
DR   Q43744, MDHM_BRANA ;  O02640, MDHM_CAEEL ;  P86074, MDHM_CAPAA ;
DR   Q42686, MDHM_CHLRE ;  P17783, MDHM_CITLA ;  P46487, MDHM_EUCGU ;
DR   P83373, MDHM_FRAAN ;  P40926, MDHM_HUMAN ;  P84209, MDHM_IMPCY ;
DR   Q4R568, MDHM_MACFA ;  P08249, MDHM_MOUSE ;  P00346, MDHM_PIG   ;
DR   Q5NVR2, MDHM_PONAB ;  P04636, MDHM_RAT   ;  P37227, MDHM_SCHMA ;
DR   Q9Y7R8, MDHM_SCHPO ;  P82816, MDHM_TOBAC ;  P17505, MDHM_YEAST ;
DR   Q9SN86, MDHP_ARATH ;  P32419, MDHP_YEAST ;  A1TP96, MDH_ACIAC  ;
DR   Q6F7X1, MDH_ACIAD  ;  B7GW58, MDH_ACIB3  ;  B7I9D2, MDH_ACIB5  ;
DR   B2HZ52, MDH_ACIBC  ;  B0VQX5, MDH_ACIBS  ;  A3M928, MDH_ACIBT  ;
DR   B0V6R7, MDH_ACIBY  ;  A5G320, MDH_ACICJ  ;  P80540, MDH_ACIDE  ;
DR   B9MBP0, MDH_ACIET  ;  A1W9K7, MDH_ACISJ  ;  P19977, MDH_ACTMI  ;
DR   A3N1U6, MDH_ACTP2  ;  B3H269, MDH_ACTP7  ;  B0BQN0, MDH_ACTPJ  ;
DR   Q5U907, MDH_ACTSZ  ;  A0KG16, MDH_AERHH  ;  Q9YEA1, MDH_AERPE  ;
DR   A4SIV0, MDH_AERS4  ;  B9JCF5, MDH_AGRRK  ;  Q7CWK7, MDH_AGRT5  ;
DR   B9JTS9, MDH_AGRVS  ;  B2UKY5, MDH_AKKM8  ;  Q0VQ52, MDH_ALCBS  ;
DR   Q0ABE6, MDH_ALHEH  ;  B6EL39, MDH_ALISL  ;  B4RRT5, MDH_ALTMD  ;
DR   B9KIH0, MDH_ANAMF  ;  Q5PAV3, MDH_ANAMM  ;  Q2GK85, MDH_ANAPZ  ;
DR   Q3MDN9, MDH_ANAVT  ;  B7GGT8, MDH_ANOFW  ;  Q9ZF99, MDH_AQUAR  ;
DR   A8EUE8, MDH_ARCB4  ;  O08349, MDH_ARCFU  ;  Q5NYA9, MDH_AROAE  ;
DR   A1R2B5, MDH_ARTAT  ;  A8ILC6, MDH_AZOC5  ;  A1K5Q9, MDH_AZOSB  ;
DR   A7Z7J8, MDH_BACA2  ;  C3PAI1, MDH_BACAA  ;  C3L8X1, MDH_BACAC  ;
DR   A0RJJ0, MDH_BACAH  ;  Q6HSF4, MDH_BACAN  ;  B7JRW5, MDH_BACC0  ;
DR   Q72ZE5, MDH_BACC1  ;  B7IJZ0, MDH_BACC2  ;  C1EUT6, MDH_BACC3  ;
DR   B7HFA6, MDH_BACC4  ;  B7HRN2, MDH_BACC7  ;  A7GTN7, MDH_BACCN  ;
DR   B9J092, MDH_BACCQ  ;  Q817F9, MDH_BACCR  ;  Q633K5, MDH_BACCZ  ;
DR   Q5L8Z8, MDH_BACFN  ;  Q64P62, MDH_BACFR  ;  Q9K849, MDH_BACHD  ;
DR   Q6HCU0, MDH_BACHK  ;  Q59202, MDH_BACIS  ;  Q65G89, MDH_BACLD  ;
DR   A8FG47, MDH_BACP2  ;  Q5WEG2, MDH_BACSK  ;  P49814, MDH_BACSU  ;
DR   Q9X4K8, MDH_BACTC  ;  Q8A0W0, MDH_BACTN  ;  A9VJQ4, MDH_BACWK  ;
DR   A1UQV8, MDH_BARBK  ;  Q6G1M0, MDH_BARHE  ;  Q6FYD0, MDH_BARQU  ;
DR   A9IZV5, MDH_BART1  ;  P61973, MDH_BDEBA  ;  B2IG85, MDH_BEII9  ;
DR   Q2L068, MDH_BORA1  ;  Q7WD94, MDH_BORBR  ;  Q7W5Q8, MDH_BORPA  ;
DR   A9IIS3, MDH_BORPD  ;  Q7VW97, MDH_BORPE  ;  Q89X59, MDH_BRAJA  ;
DR   A5E935, MDH_BRASB  ;  A4YKC5, MDH_BRASO  ;  P80542, MDH_BREDI  ;
DR   P80543, MDH_BREVE  ;  B2S881, MDH_BRUA1  ;  Q2YLR9, MDH_BRUA2  ;
DR   Q57AX1, MDH_BRUAB  ;  A9M8R3, MDH_BRUC2  ;  C0RFH2, MDH_BRUMB  ;
DR   Q8YJE7, MDH_BRUME  ;  A5VSQ4, MDH_BRUO2  ;  B0CIT1, MDH_BRUSI  ;
DR   Q8FYF4, MDH_BRUSU  ;  Q1BM38, MDH_BURCA  ;  B1K394, MDH_BURCC  ;
DR   P80537, MDH_BURCE  ;  A0AZ43, MDH_BURCH  ;  B4EFB0, MDH_BURCJ  ;
DR   Q0BAF9, MDH_BURCM  ;  A9AMD5, MDH_BURM1  ;  A3MBR2, MDH_BURM7  ;
DR   A2S105, MDH_BURM9  ;  Q62AG8, MDH_BURMA  ;  A1UZ10, MDH_BURMS  ;
DR   A3P7Q9, MDH_BURP0  ;  Q3JKE9, MDH_BURP1  ;  A3NM97, MDH_BURP6  ;
DR   B2JQD2, MDH_BURP8  ;  B2T9P8, MDH_BURPP  ;  P80536, MDH_BURPS  ;
DR   Q393V1, MDH_BURS3  ;  Q13S42, MDH_BURXL  ;  A8MAC1, MDH_CALMQ  ;
DR   Q9PHY2, MDH_CAMJE  ;  B8GVT2, MDH_CAUCN  ;  Q9A2B1, MDH_CAUCR  ;
DR   B0T6C1, MDH_CAUSK  ;  B3PHI3, MDH_CELJU  ;  P80040, MDH_CHLAA  ;
DR   Q5L5E3, MDH_CHLAB  ;  B8GDA2, MDH_CHLAD  ;  Q3AS98, MDH_CHLCH  ;
DR   Q822E9, MDH_CHLCV  ;  Q255I4, MDH_CHLFF  ;  B3EEE5, MDH_CHLL2  ;
DR   Q9PK18, MDH_CHLMU  ;  B3QPY9, MDH_CHLP8  ;  B3EP06, MDH_CHLPB  ;
DR   A1BHN9, MDH_CHLPD  ;  Q9Z6N1, MDH_CHLPN  ;  B9LLP6, MDH_CHLSY  ;
DR   B0B7U5, MDH_CHLT2  ;  B3QSH8, MDH_CHLT3  ;  Q3KLX8, MDH_CHLTA  ;
DR   B0BC10, MDH_CHLTB  ;  P80039, MDH_CHLTE  ;  O84381, MDH_CHLTR  ;
DR   P0C890, MDH_CHLVI  ;  Q7NZ60, MDH_CHRVO  ;  A8AQC8, MDH_CITK8  ;
DR   Q47VL0, MDH_COLP3  ;  P61974, MDH_CORDI  ;  Q8FN62, MDH_COREF  ;
DR   A4QGA0, MDH_CORGB  ;  Q8NN33, MDH_CORGL  ;  Q4JWV0, MDH_CORJK  ;
DR   B6J7Q0, MDH_COXB1  ;  B6IZN7, MDH_COXB2  ;  A9KFT9, MDH_COXBN  ;
DR   A9NDV1, MDH_COXBR  ;  Q83C87, MDH_COXBU  ;  Q0K8F5, MDH_CUPNH  ;
DR   Q46YU4, MDH_CUPPJ  ;  B3R570, MDH_CUPTR  ;  Q11QQ3, MDH_CYTH3  ;
DR   Q47C34, MDH_DECAR  ;  Q3Z9A4, MDH_DEHE1  ;  A5FS18, MDH_DEHSB  ;
DR   Q3ZZJ7, MDH_DEHSC  ;  C1CY73, MDH_DEIDV  ;  Q1IWC9, MDH_DEIGD  ;
DR   Q9RXI8, MDH_DEIRA  ;  P80539, MDH_DELAC  ;  A9BVK0, MDH_DELAS  ;
DR   B1I3T1, MDH_DESAP  ;  Q6AQI3, MDH_DESPS  ;  A4J5N8, MDH_DESRM  ;
DR   A8LJK6, MDH_DINSH  ;  A7ZSD0, MDH_ECO24  ;  B7UJW8, MDH_ECO27  ;
DR   B7MBZ7, MDH_ECO45  ;  B7LHU4, MDH_ECO55  ;  P61891, MDH_ECO57  ;
DR   B5YSW2, MDH_ECO5E  ;  B7NKU9, MDH_ECO7I  ;  B7N0M1, MDH_ECO81  ;
DR   B7M0U8, MDH_ECO8A  ;  C4ZSX4, MDH_ECOBW  ;  B1XHK9, MDH_ECODH  ;
DR   A8A545, MDH_ECOHS  ;  A1AGC9, MDH_ECOK1  ;  Q0TCN0, MDH_ECOL5  ;
DR   P61890, MDH_ECOL6  ;  B1IQP3, MDH_ECOLC  ;  P61889, MDH_ECOLI  ;
DR   B7NDL4, MDH_ECOLU  ;  B6I1V4, MDH_ECOSE  ;  B1LGK2, MDH_ECOSM  ;
DR   Q1R6A3, MDH_ECOUT  ;  C5BF98, MDH_EDWI9  ;  Q3YS64, MDH_EHRCJ  ;
DR   Q2GGI2, MDH_EHRCR  ;  Q5FGT9, MDH_EHRRG  ;  Q5HBC0, MDH_EHRRW  ;
DR   A4WF48, MDH_ENT38  ;  A7MNR3, MDH_ENTS8  ;  Q6D9D1, MDH_ERWCT  ;
DR   B2VGW7, MDH_ERWT9  ;  B7LRL0, MDH_ESCF3  ;  A5FHP3, MDH_FLAJ1  ;
DR   Q0RE66, MDH_FRAAA  ;  Q8GNM0, MDH_FRANO  ;  B0TZT2, MDH_FRAP2  ;
DR   Q2J7E7, MDH_FRASC  ;  Q14IT0, MDH_FRAT1  ;  A7NC13, MDH_FRATF  ;
DR   Q2A3K7, MDH_FRATH  ;  B2SH29, MDH_FRATM  ;  A0Q6K3, MDH_FRATN  ;
DR   A4IY35, MDH_FRATW  ;  B5EIU8, MDH_GEOBB  ;  Q5KWB7, MDH_GEOKA  ;
DR   B3E9R5, MDH_GEOLS  ;  Q39VY0, MDH_GEOMG  ;  B9M1D2, MDH_GEOSF  ;
DR   Q74D53, MDH_GEOSL  ;  C6E487, MDH_GEOSM  ;  C5D654, MDH_GEOSW  ;
DR   A4IRP9, MDH_GEOTN  ;  A5G3L2, MDH_GEOUR  ;  Q7NHJ3, MDH_GLOVI  ;
DR   Q7VP41, MDH_HAEDU  ;  Q4QL89, MDH_HAEI8  ;  A5UCQ1, MDH_HAEIE  ;
DR   A5UIX3, MDH_HAEIG  ;  P44427, MDH_HAEIN  ;  B8F5K4, MDH_HAEPS  ;
DR   Q0I491, MDH_HAES1  ;  B0UUR6, MDH_HAES2  ;  A1WV94, MDH_HALHL  ;
DR   Q07841, MDH_HALMA  ;  B0R7Q0, MDH_HALS3  ;  Q9HMV8, MDH_HALSA  ;
DR   Q9P9L2, MDH_HALVD  ;  P80037, MDH_HELGE  ;  Q7VFV4, MDH_HELHP  ;
DR   B0TCL9, MDH_HELMI  ;  A4G5Z9, MDH_HERAR  ;  B4U831, MDH_HYDS0  ;
DR   Q0BXA0, MDH_HYPNA  ;  Q5R030, MDH_IDILO  ;  A6SY47, MDH_JANMA  ;
DR   Q28U77, MDH_JANSC  ;  P19978, MDH_KIBAR  ;  P61894, MDH_KLEOX  ;
DR   B5XSQ7, MDH_KLEP3  ;  A6TEQ3, MDH_KLEP7  ;  P0C1G4, MDH_KLEPN  ;
DR   P0C1G5, MDH_KLEPR  ;  P61896, MDH_KLEVA  ;  B2GKC8, MDH_KOCRD  ;
DR   C1DB66, MDH_LARHH  ;  Q5X2T6, MDH_LEGPA  ;  A5IEF4, MDH_LEGPC  ;
DR   Q5ZT13, MDH_LEGPH  ;  Q5WU94, MDH_LEGPL  ;  B0SF41, MDH_LEPBA  ;
DR   Q04RS5, MDH_LEPBJ  ;  Q051U6, MDH_LEPBL  ;  B0SN74, MDH_LEPBP  ;
DR   B1Y8A3, MDH_LEPCP  ;  P61975, MDH_LEPIC  ;  Q8F4A2, MDH_LEPIN  ;
DR   Q2W064, MDH_MAGSA  ;  A0L5T9, MDH_MAGSM  ;  Q65T37, MDH_MANSM  ;
DR   Q0AKT3, MDH_MARMM  ;  Q11CV9, MDH_MESSB  ;  Q8TSH7, MDH_METAC  ;
DR   Q46BQ2, MDH_METBF  ;  B7KVX2, MDH_METC4  ;  Q60B71, MDH_METCA  ;
DR   Q84FY8, MDH_METEA  ;  A9W386, MDH_METEP  ;  P16142, MDH_METFV  ;
DR   Q60176, MDH_METJA  ;  Q8TWG5, MDH_METKA  ;  Q8PVJ7, MDH_METMA  ;
DR   Q6LZI3, MDH_METMP  ;  B8IJB4, MDH_METNO  ;  B1ZG93, MDH_METPB  ;
DR   A2SHT9, MDH_METPP  ;  B1LZN1, MDH_METRJ  ;  B0UCF0, MDH_METS4  ;
DR   B8EM38, MDH_METSB  ;  Q2NGI3, MDH_METST  ;  O26290, MDH_METTH  ;
DR   P19979, MDH_MICGL  ;  Q6AW21, MDH_MORJA  ;  Q7X3X5, MDH_MORS2  ;
DR   P48364, MDH_MORS5  ;  A0QCI6, MDH_MYCA1  ;  P0A5J7, MDH_MYCBO  ;
DR   A1KI28, MDH_MYCBP  ;  C1AMN4, MDH_MYCBT  ;  P50917, MDH_MYCLE  ;
DR   B2HRH5, MDH_MYCMM  ;  P61976, MDH_MYCPA  ;  A5U1T8, MDH_MYCTA  ;
DR   P0A5J6, MDH_MYCTU  ;  A0PVV1, MDH_MYCUA  ;  A1T9L9, MDH_MYCVP  ;
DR   Q6ZZC6, MDH_MYXXA  ;  Q3IU43, MDH_NATPD  ;  Q2GCH6, MDH_NEOSM  ;
DR   P10887, MDH_NITAL  ;  Q0AFK6, MDH_NITEC  ;  Q82WB9, MDH_NITEU  ;
DR   Q1QQR2, MDH_NITHX  ;  A9A450, MDH_NITMS  ;  Q2YAQ4, MDH_NITMU  ;
DR   Q3J7E7, MDH_NITOC  ;  A6Q388, MDH_NITSB  ;  Q3SVK5, MDH_NITWN  ;
DR   Q5YTI1, MDH_NOCFA  ;  A1SMP3, MDH_NOCSJ  ;  B2J5F8, MDH_NOSP7  ;
DR   Q8YP78, MDH_NOSS1  ;  Q2G946, MDH_NOVAD  ;  Q8EPE2, MDH_OCEIH  ;
DR   A6WXE7, MDH_OCHA4  ;  A6L903, MDH_PARD8  ;  A7HT37, MDH_PARL1  ;
DR   Q6MAA3, MDH_PARUW  ;  Q9CN86, MDH_PASMU  ;  P61897, MDH_PECCC  ;
DR   C6DKH1, MDH_PECCP  ;  Q3A5S0, MDH_PELCD  ;  Q3B2R4, MDH_PELLD  ;
DR   B4SFQ8, MDH_PELPB  ;  Q4FP28, MDH_PELUB  ;  P19980, MDH_PHEIM  ;
DR   Q7MYW9, MDH_PHOLL  ;  P37226, MDH_PHOPR  ;  Q6L0C3, MDH_PICTO  ;
DR   P19981, MDH_PLAVE  ;  A1VRQ1, MDH_POLNA  ;  B1XV63, MDH_POLNS  ;
DR   Q126N9, MDH_POLSJ  ;  A4SWW0, MDH_POLSQ  ;  B4S9F1, MDH_PROA2  ;
DR   Q6A6Z5, MDH_PROAC  ;  B4F2A1, MDH_PROMH  ;  A4SFT4, MDH_PROVI  ;
DR   Q15YH0, MDH_PSEA6  ;  Q3IFH4, MDH_PSEHT  ;  P80538, MDH_PSEIN  ;
DR   P85920, MDH_PSEMZ  ;  A5VY92, MDH_PSEP1  ;  B0KMD1, MDH_PSEPG  ;
DR   Q88Q44, MDH_PSEPK  ;  Q4FQU7, MDH_PSYA2  ;  Q1Q932, MDH_PSYCK  ;
DR   A1SRP8, MDH_PSYIN  ;  A5WGM2, MDH_PSYWF  ;  Q9V0D5, MDH_PYRAB  ;
DR   Q8ZVB2, MDH_PYRAE  ;  A3MWU9, MDH_PYRCJ  ;  O59028, MDH_PYRHO  ;
DR   Q1LKG0, MDH_RALME  ;  B2U705, MDH_RALPJ  ;  Q8XXW5, MDH_RALSO  ;
DR   P61895, MDH_RAOTE  ;  B3PQ91, MDH_RHIE6  ;  Q2K3E9, MDH_RHIEC  ;
DR   O33525, MDH_RHIL3  ;  Q98EC4, MDH_RHILO  ;  B5ZSS0, MDH_RHILW  ;
DR   Q9EYJ6, MDH_RHIME  ;  C3M9U0, MDH_RHISN  ;  Q7UNC6, MDH_RHOBA  ;
DR   B6IYP5, MDH_RHOCS  ;  C1B155, MDH_RHOOB  ;  Q2J3G8, MDH_RHOP2  ;
DR   Q07UX5, MDH_RHOP5  ;  P80458, MDH_RHOPA  ;  Q13DR6, MDH_RHOPS  ;
DR   B3Q761, MDH_RHOPT  ;  Q2RV34, MDH_RHORT  ;  P80459, MDH_RHORU  ;
DR   A3PN14, MDH_RHOS1  ;  Q3IZ83, MDH_RHOS4  ;  A4WNM7, MDH_RHOS5  ;
DR   B9KNB4, MDH_RHOSK  ;  Q0S365, MDH_RHOSR  ;  C3PN92, MDH_RICAE  ;
DR   A8GN82, MDH_RICAH  ;  A8GWI0, MDH_RICB8  ;  Q1RIT9, MDH_RICBR  ;
DR   A8EZ58, MDH_RICCK  ;  Q92IA0, MDH_RICCN  ;  Q4ULY2, MDH_RICFE  ;
DR   Q9ZDF3, MDH_RICPR  ;  C4K2E2, MDH_RICPU  ;  B0BXA8, MDH_RICRO  ;
DR   A8GRV2, MDH_RICRS  ;  Q68WZ8, MDH_RICTY  ;  A7NG29, MDH_ROSCS  ;
DR   Q169U9, MDH_ROSDO  ;  A5UPY6, MDH_ROSS1  ;  Q1AWH4, MDH_RUBXD  ;
DR   Q21K60, MDH_SACD2  ;  A4FFX3, MDH_SACEN  ;  B5F7L9, MDH_SALA4  ;
DR   A9MNX5, MDH_SALAR  ;  Q57JA9, MDH_SALCH  ;  B5FIT7, MDH_SALDC  ;
DR   B5R0N2, MDH_SALEP  ;  B5REV7, MDH_SALG2  ;  B4TJT3, MDH_SALHS  ;
DR   Q59838, MDH_SALMU  ;  B4T769, MDH_SALNS  ;  Q7WS85, MDH_SALPA  ;
DR   A9N855, MDH_SALPB  ;  C0PZQ4, MDH_SALPC  ;  B5BGR3, MDH_SALPK  ;
DR   Q2S289, MDH_SALRD  ;  B4TWK9, MDH_SALSV  ;  Q8Z3E0, MDH_SALTI  ;
DR   P25077, MDH_SALTY  ;  A8G8Y7, MDH_SERP5  ;  A1S3C4, MDH_SHEAM  ;
DR   B8EB55, MDH_SHEB2  ;  A3D075, MDH_SHEB5  ;  A6WSM1, MDH_SHEB8  ;
DR   A9L340, MDH_SHEB9  ;  Q12R11, MDH_SHEDO  ;  Q07YA5, MDH_SHEFN  ;
DR   B0TUH8, MDH_SHEHH  ;  A3QB91, MDH_SHELP  ;  P82177, MDH_SHEON  ;
DR   A8H0U0, MDH_SHEPA  ;  A4YAE8, MDH_SHEPC  ;  B8CSY7, MDH_SHEPW  ;
DR   A0L113, MDH_SHESA  ;  A8FRU0, MDH_SHESH  ;  Q0HEW2, MDH_SHESM  ;
DR   Q0HZ38, MDH_SHESR  ;  A1RFX8, MDH_SHESW  ;  B1KGG7, MDH_SHEWM  ;
DR   B2U1U9, MDH_SHIB3  ;  Q31WA4, MDH_SHIBS  ;  Q32BA3, MDH_SHIDS  ;
DR   Q0T052, MDH_SHIF8  ;  Q83Q04, MDH_SHIFL  ;  Q3YX11, MDH_SHISS  ;
DR   Q5LXE1, MDH_SILPO  ;  A6UDP3, MDH_SINMW  ;  A9EZV5, MDH_SORC5  ;
DR   Q1GQY3, MDH_SPHAL  ;  A5V5U9, MDH_SPHWW  ;  B9DK67, MDH_STACT  ;
DR   Q5HR46, MDH_STAEQ  ;  Q8CQ25, MDH_STAES  ;  Q49VN8, MDH_STAS1  ;
DR   P80541, MDH_STEMA  ;  P19982, MDH_STRAR  ;  Q82HS2, MDH_STRAW  ;
DR   Q9K3J3, MDH_STRCO  ;  B1W3N4, MDH_STRGG  ;  B4SLI5, MDH_STRM5  ;
DR   B2FQL8, MDH_STRMK  ;  P19983, MDH_STRRS  ;  P11386, MDH_SULAC  ;
DR   Q30RQ5, MDH_SULDN  ;  Q97VN4, MDH_SULSO  ;  P58407, MDH_SULTO  ;
DR   Q67LB8, MDH_SYMTH  ;  A0LFF8, MDH_SYNFM  ;  Q55383, MDH_SYNY3  ;
DR   C5BU70, MDH_TERTT  ;  Q9HJL5, MDH_THEAC  ;  P33163, MDH_THEAL  ;
DR   Q47TT4, MDH_THEFY  ;  B9KZS7, MDH_THERP  ;  P61977, MDH_THET2  ;
DR   Q5SKV7, MDH_THET8  ;  Q704B2, MDH_THETE  ;  P10584, MDH_THETH  ;
DR   Q979N9, MDH_THEVO  ;  B8GPC3, MDH_THISH  ;  C5CSI5, MDH_VARPS  ;
DR   A1WR02, MDH_VEREI  ;  Q9KUT3, MDH_VIBCH  ;  Q5E875, MDH_VIBF1  ;
DR   B5FGF5, MDH_VIBFM  ;  A7MWD3, MDH_VIBHB  ;  Q6AW23, MDH_VIBMA  ;
DR   Q9L8F6, MDH_VIBMI  ;  Q87SU7, MDH_VIBPA  ;  B7VID0, MDH_VIBSL  ;
DR   Q8DEC2, MDH_VIBVU  ;  Q7MP97, MDH_VIBVY  ;  Q73G44, MDH_WOLPM  ;
DR   B3CM44, MDH_WOLPP  ;  Q7M9A7, MDH_WOLSU  ;  Q5GT41, MDH_WOLTR  ;
DR   C0R4Y0, MDH_WOLWR  ;  Q8PNP8, MDH_XANAC  ;  Q3BWU8, MDH_XANC5  ;
DR   Q4URH2, MDH_XANC8  ;  B0RU49, MDH_XANCB  ;  Q8PC25, MDH_XANCP  ;
DR   Q2P736, MDH_XANOM  ;  B2SMP6, MDH_XANOP  ;  Q5H496, MDH_XANOR  ;
DR   A7IBL9, MDH_XANP2  ;  B2I8M1, MDH_XYLF2  ;  Q9PE17, MDH_XYLFA  ;
DR   B0U5Q1, MDH_XYLFM  ;  Q87E35, MDH_XYLFT  ;  A1JIV0, MDH_YERE8  ;
DR   A7FMU2, MDH_YERP3  ;  Q1CBY7, MDH_YERPA  ;  B2K2N5, MDH_YERPB  ;
DR   P61892, MDH_YERPE  ;  A9R584, MDH_YERPG  ;  Q1CEJ3, MDH_YERPN  ;
DR   A4TRK3, MDH_YERPP  ;  P0C7R5, MDH_YERPS  ;  B1JMK1, MDH_YERPY  ;
//
ID   1.1.1.38
DE   Malate dehydrogenase (oxaloacetate-decarboxylating).
AN   Malic enzyme.
AN   NAD-malic enzyme.
AN   Pyruvic-malic carboxylase.
CA   (S)-malate + NAD(+) = pyruvate + CO(2) + NADH.
CC   -!- Also decarboxylates added oxaloacetate.
PR   PROSITE; PDOC00294;
DR   Q6LQM6, MAO11_PHOPR;  Q7MLG3, MAO11_VIBVY;  Q6LHK5, MAO12_PHOPR;
DR   Q7MJC0, MAO12_VIBVY;  Q6FFL8, MAO1_ACIAD ;  A0KHR8, MAO1_AERHH ;
DR   A4SKE9, MAO1_AERS4 ;  B6EK11, MAO1_ALISL ;  P54572, MAO1_BACSU ;
DR   Q6MJE4, MAO1_BDEBA ;  A8AGN6, MAO1_CITK8 ;  Q47WB0, MAO1_COLP3 ;
DR   A7ZLS1, MAO1_ECO24 ;  B7URL9, MAO1_ECO27 ;  B7MMW1, MAO1_ECO45 ;
DR   B7L7H9, MAO1_ECO55 ;  Q8XAS9, MAO1_ECO57 ;  B5Z1T9, MAO1_ECO5E ;
DR   B7NHU3, MAO1_ECO7I ;  B7MUR3, MAO1_ECO81 ;  B7LZ73, MAO1_ECO8A ;
DR   C4ZWP8, MAO1_ECOBW ;  B1XE70, MAO1_ECODH ;  A8A036, MAO1_ECOHS ;
DR   A1AB75, MAO1_ECOK1 ;  Q0THU1, MAO1_ECOL5 ;  Q8FHH1, MAO1_ECOL6 ;
DR   B1IRX9, MAO1_ECOLC ;  P26616, MAO1_ECOLI ;  B7N4P2, MAO1_ECOLU ;
DR   B1LFD8, MAO1_ECOSM ;  Q1RBT9, MAO1_ECOUT ;  C5BCM3, MAO1_EDWI9 ;
DR   A4WAJ3, MAO1_ENT38 ;  A7MN74, MAO1_ENTS8 ;  Q6D3B3, MAO1_ERWCT ;
DR   B2VIF2, MAO1_ERWT9 ;  B7LQX1, MAO1_ESCF3 ;  Q5QWY8, MAO1_IDILO ;
DR   B5XX25, MAO1_KLEP3 ;  A6T9K7, MAO1_KLEP7 ;  C6DDS6, MAO1_PECCP ;
DR   Q7N6K4, MAO1_PHOLL ;  B4ESY2, MAO1_PROMH ;  Q48LC8, MAO1_PSE14 ;
DR   A6V1V5, MAO1_PSEA7 ;  B7UWK9, MAO1_PSEA8 ;  Q02QW0, MAO1_PSEAB ;
DR   Q9HYD5, MAO1_PSEAE ;  Q87Y79, MAO1_PSESM ;  Q4ZW63, MAO1_PSEU2 ;
DR   Q4FRX3, MAO1_PSYA2 ;  Q1QC40, MAO1_PSYCK ;  A1SSC6, MAO1_PSYIN ;
DR   B5F5W5, MAO1_SALA4 ;  A9MR05, MAO1_SALAR ;  Q57P88, MAO1_SALCH ;
DR   B5FHJ6, MAO1_SALDC ;  B5QTN6, MAO1_SALEP ;  B5RAB4, MAO1_SALG2 ;
DR   B4TII8, MAO1_SALHS ;  B4T5V6, MAO1_SALNS ;  Q5PHY7, MAO1_SALPA ;
DR   A9MYU8, MAO1_SALPB ;  B4TW15, MAO1_SALSV ;  Q8Z728, MAO1_SALTI ;
DR   Q8ZPE8, MAO1_SALTY ;  A8GC31, MAO1_SERP5 ;  A1S8W7, MAO1_SHEAM ;
DR   B8E835, MAO1_SHEB2 ;  A3D0E1, MAO1_SHEB5 ;  A6WSH0, MAO1_SHEB8 ;
DR   A9L2F4, MAO1_SHEB9 ;  Q12RA0, MAO1_SHEDO ;  Q086X9, MAO1_SHEFN ;
DR   B0TRQ2, MAO1_SHEHH ;  A3QH80, MAO1_SHELP ;  Q8EAP2, MAO1_SHEON ;
DR   A8H7G5, MAO1_SHEPA ;  A4Y3I1, MAO1_SHEPC ;  B8CQT6, MAO1_SHEPW ;
DR   A0KT69, MAO1_SHESA ;  A8FZ49, MAO1_SHESH ;  Q0HFA9, MAO1_SHESM ;
DR   Q0HYM7, MAO1_SHESR ;  A1RNF8, MAO1_SHESW ;  B1KFN0, MAO1_SHEWM ;
DR   B2U1M1, MAO1_SHIB3 ;  Q320R8, MAO1_SHIBS ;  Q0T457, MAO1_SHIF8 ;
DR   Q83ML6, MAO1_SHIFL ;  Q3Z1M2, MAO1_SHISS ;  Q2NUD3, MAO1_SODGM ;
DR   A5F1Z0, MAO1_VIBC3 ;  Q9KSR8, MAO1_VIBCH ;  Q5E4J3, MAO1_VIBF1 ;
DR   B5FEY5, MAO1_VIBFM ;  A7N025, MAO1_VIBHB ;  Q87Q92, MAO1_VIBPA ;
DR   Q8D911, MAO1_VIBVU ;  A1JTY5, MAO1_YERE8 ;  A7FJK4, MAO1_YERP3 ;
DR   Q1C9U8, MAO1_YERPA ;  B2JZJ5, MAO1_YERPB ;  Q8ZG09, MAO1_YERPE ;
DR   Q1CGT4, MAO1_YERPN ;  A4TKN8, MAO1_YERPP ;  Q66C80, MAO1_YERPS ;
DR   B1JPZ6, MAO1_YERPY ;  P45868, MAO2_BACSU ;  O34389, MAO3_BACSU ;
DR   O34962, MAO4_BACSU ;  P27443, MAOM_ASCSU ;  P23368, MAOM_HUMAN ;
DR   Q99KE1, MAOM_MOUSE ;  P36013, MAOM_YEAST ;  P16468, MAOX_GEOSE ;
DR   P71880, MAOX_MYCTU ;  P40375, MAOX_SCHPO ;
//
ID   1.1.1.39
DE   Malate dehydrogenase (decarboxylating).
AN   Malic enzyme.
AN   NAD-malic enzyme.
AN   Pyruvic-malic carboxylase.
CA   (S)-malate + NAD(+) = pyruvate + CO(2) + NADH.
CC   -!- Does not decarboxylate added oxaloacetate.
PR   PROSITE; PDOC00294;
DR   O30807, MAO1_RHIME ;  P37224, MAOM_AMAHP ;  P37221, MAOM_SOLTU ;
DR   P37225, MAON_SOLTU ;
//
ID   1.1.1.40
DE   Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)).
AN   Malic enzyme.
AN   NADP-malic enzyme.
AN   Pyruvic-malic carboxylase.
CA   (S)-malate + NADP(+) = pyruvate + CO(2) + NADPH.
CC   -!- Also decarboxylates added oxaloacetate.
PR   PROSITE; PDOC00294;
DR   P76558, MAO2_ECOLI ;  P43837, MAO2_HAEIN ;  O30808, MAO2_RHIME ;
DR   Q9ZDF6, MAO2_RICPR ;  Q9ZFV8, MAO2_SALTY ;  P36444, MAOC_FLAPR ;
DR   P22178, MAOC_FLATR ;  P16243, MAOC_MAIZE ;  P43279, MAOC_ORYSJ ;
DR   P37222, MAOC_SOLLC ;  P78715, MAOH_NEOFR ;  Q16798, MAON_HUMAN ;
DR   Q8BMF3, MAON_MOUSE ;  P28227, MAOX_ANAPL ;  Q92060, MAOX_CHICK ;
DR   P40927, MAOX_COLLI ;  Q6TU48, MAOX_DICDI ;  P48163, MAOX_HUMAN ;
DR   P37223, MAOX_MESCR ;  P06801, MAOX_MOUSE ;  P12628, MAOX_PHAVU ;
DR   Q29558, MAOX_PIG   ;  P84539, MAOX_POPEU ;  P34105, MAOX_POPTR ;
DR   P13697, MAOX_RAT   ;  P51615, MAOX_VITVI ;
//
ID   1.1.1.41
DE   Isocitrate dehydrogenase (NAD(+)).
AN   Beta-ketoglutaric-isocitric carboxylase.
AN   IDH.
AN   Isocitrate dehydrogenase (NAD).
AN   Isocitric acid dehydrogenase.
AN   Isocitric dehydrogenase.
AN   NAD dependent isocitrate dehydrogenase.
AN   NAD isocitrate dehydrogenase.
AN   NAD isocitric dehydrogenase.
AN   NAD-linked isocitrate dehydrogenase.
AN   NAD-specific isocitrate dehydrogenase.
AN   Nicotinamide adenine dinucleotide isocitrate dehydrogenase.
CA   Isocitrate + NAD(+) = 2-oxoglutarate + CO(2) + NADH.
CF   Manganese or magnesium.
CC   -!- Unlike EC 1.1.1.42, oxalosuccinate cannot be used as a substrate.
CC   -!- In eukaryotes, isocitrate dehydrogenase exists in two forms: an
CC       NAD(+)-linked enzyme found only in mitochondria and displaying
CC       allosteric properties, and a non-allosteric, NADP(+)-linked enzyme
CC       that is found in both mitochondria and cytoplasm.
CC   -!- The enzyme from some species can also use NADP(+) but much more
CC       slowly.
PR   PROSITE; PDOC00389;
DR   O13302, IDH1_AJECA ;  Q8LFC0, IDH1_ARATH ;  O94229, IDH1_KLULA ;
DR   O13696, IDH1_SCHPO ;  P28834, IDH1_YEAST ;  P93032, IDH2_ARATH ;
DR   O94230, IDH2_KLULA ;  Q9USP8, IDH2_SCHPO ;  P28241, IDH2_YEAST ;
DR   P41563, IDH3A_BOVIN;  Q93714, IDH3A_CAEEL;  P54836, IDH3A_CANFA;
DR   Q9VWH4, IDH3A_DROME;  P50213, IDH3A_HUMAN;  Q28480, IDH3A_MACFA;
DR   P86225, IDH3A_MESAU;  Q9D6R2, IDH3A_MOUSE;  P56471, IDH3A_PIG  ;
DR   Q5R678, IDH3A_PONAB;  Q99NA5, IDH3A_RAT  ;  O77784, IDH3B_BOVIN;
DR   Q93353, IDH3B_CAEEL;  O43837, IDH3B_HUMAN;  Q28479, IDH3B_MACFA;
DR   P56472, IDH3B_PIG  ;  Q5RBT4, IDH3B_PONAB;  Q68FX0, IDH3B_RAT  ;
DR   Q58CP0, IDH3G_BOVIN;  P51553, IDH3G_HUMAN;  P41564, IDH3G_MACFA;
DR   P41566, IDH3G_PIG  ;  O81796, IDH3_ARATH ;  Q945K7, IDH5_ARATH ;
DR   Q8LG77, IDH6_ARATH ;  Q55BI2, IDHA_DICDI ;  Q54B68, IDHB_DICDI ;
DR   P70404, IDHG1_MOUSE;  P41565, IDHG1_RAT  ;  Q8BPC6, IDHG2_MOUSE;
DR   Q4QQT5, IDHG2_RAT  ;
//
ID   1.1.1.42
DE   Isocitrate dehydrogenase (NADP(+)).
AN   Dual-cofactor-specific isocitrate dehydrogenase.
AN   IDH.
AN   IDP.
AN   Isocitrate (NADP) dehydrogenase.
AN   Isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase.
AN   Isocitrate dehydrogenase (NADP).
AN   Isocitrate dehydrogenase (NADP-dependent).
AN   NADP isocitric dehydrogenase.
AN   NADP(+)-ICDH.
AN   NADP(+)-IDH.
AN   NADP(+)-linked isocitrate dehydrogenase.
AN   NADP-dependent isocitrate dehydrogenase.
AN   NADP-dependent isocitric dehydrogenase.
AN   NADP-linked isocitrate dehydrogenase.
AN   NADP-specific isocitrate dehydrogenase.
AN   Oxalosuccinate decarboxylase.
AN   Oxalsuccinic decarboxylase.
AN   Triphosphopyridine nucleotide-linked isocitrate dehydrogenase-
AN   oxalosuccinate carboxylase.
CA   Isocitrate + NADP(+) = 2-oxoglutarate + CO(2) + NADPH.
CF   Manganese or magnesium.
CC   -!- Unlike EC 1.1.1.41, oxalosuccinate can be used as a substrate.
CC   -!- In eukaryotes, isocitrate dehydrogenase exists in two forms: an
CC       NAD(+)-linked enzyme found only in mitochondria and displaying
CC       allosteric properties, and a non-allosteric, NADP(+)-linked enzyme
CC       that is found in both mitochondria and cytoplasm.
CC   -!- The enzyme from some species can also use NAD(+) but much more
CC       slowly.
PR   PROSITE; PDOC00389;
DR   O13285, IDH1_CANTR ;  P41560, IDH1_COLMA ;  O13294, IDH2_CANTR ;
DR   P41561, IDH2_COLMA ;  Q9XSG3, IDHC_BOVIN ;  Q75JR3, IDHC_DICDI ;
DR   O75874, IDHC_HUMAN ;  Q9Z2K9, IDHC_MICME ;  Q9Z2K8, IDHC_MICOH ;
DR   O88844, IDHC_MOUSE ;  P83726, IDHC_NAEFO ;  P20304, IDHC_PIG   ;
DR   Q5R9C5, IDHC_PONAB ;  P41562, IDHC_RAT   ;  Q6XUZ5, IDHC_SHEEP ;
DR   P50217, IDHC_SOLTU ;  Q06197, IDHC_SOYBN ;  P50218, IDHC_TOBAC ;
DR   P41939, IDHC_YEAST ;  P53982, IDHH_YEAST ;  P79089, IDHP_ASPNG ;
DR   Q04467, IDHP_BOVIN ;  Q75JR2, IDHP_DICDI ;  P48735, IDHP_HUMAN ;
DR   Q4R502, IDHP_MACFA ;  Q40345, IDHP_MEDSA ;  P54071, IDHP_MOUSE ;
DR   P33198, IDHP_PIG   ;  P56574, IDHP_RAT   ;  O14254, IDHP_SCHPO ;
DR   P21954, IDHP_YEAST ;  O67480, IDH_AQUAE  ;  O29610, IDH_ARCFU  ;
DR   P16100, IDH_AZOVI  ;  P39126, IDH_BACSU  ;  P96318, IDH_CALNO  ;
DR   Q8RQL9, IDH_COREF  ;  P50216, IDH_CORGL  ;  Q9ZH99, IDH_COXBU  ;
DR   P08200, IDH_ECOLI  ;  Q9ZN36, IDH_HELPJ  ;  P56063, IDH_HELPY  ;
DR   P65098, IDH_MYCBO  ;  P65097, IDH_MYCTU  ;  P50214, IDH_NOSS1  ;
DR   Q1RJU4, IDH_RICBR  ;  Q92IR7, IDH_RICCN  ;  Q4UKR1, IDH_RICFE  ;
DR   Q9ZDR0, IDH_RICPR  ;  Q68XA5, IDH_RICTY  ;  P50215, IDH_SPHYA  ;
DR   Q5HF79, IDH_STAAC  ;  P65099, IDH_STAAM  ;  P99167, IDH_STAAN  ;
DR   Q6GG12, IDH_STAAR  ;  Q6G8N2, IDH_STAAS  ;  Q8NW61, IDH_STAAW  ;
DR   Q5HNL1, IDH_STAEQ  ;  Q8CNX4, IDH_STAES  ;  Q59940, IDH_STRMU  ;
DR   Q59985, IDH_STRSL  ;  P80046, IDH_SYNY3  ;  P33197, IDH_THET8  ;
//
ID   1.1.1.43
DE   Phosphogluconate 2-dehydrogenase.
AN   6-phosphogluconate 2-dehydrogenase.
AN   6-phosphogluconic dehydrogenase.
CA   6-phospho-D-gluconate + NAD(P)(+) = 6-phospho-2-dehydro-D-gluconate +
CA   NAD(P)H.
//
ID   1.1.1.44
DE   Phosphogluconate dehydrogenase (decarboxylating).
AN   6-phosphogluconic carboxylase.
AN   6-phosphogluconic dehydrogenase.
AN   6PGD.
AN   Phosphogluconic acid dehydrogenase.
CA   6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO(2) + NADPH.
PR   PROSITE; PDOC00390;
DR   P38720, 6PGD1_YEAST;  P80859, 6PGD2_BACSU;  P53319, 6PGD2_YEAST;
DR   P37754, 6PGD9_ECOLX;  P70718, 6PGD_AGGAC ;  P52207, 6PGD_BACLI ;
DR   P12013, 6PGD_BACSU ;  P57208, 6PGD_BUCAI ;  Q9ZHD9, 6PGD_BUCAP ;
DR   Q89AX5, 6PGD_BUCBP ;  Q17761, 6PGD_CAEEL ;  O13287, 6PGD_CANAL ;
DR   P41570, 6PGD_CERCA ;  Q9PKX7, 6PGD_CHLMU ;  Q9Z8I3, 6PGD_CHLPN ;
DR   O84066, 6PGD_CHLTR ;  P41581, 6PGD_CITAM ;  P41582, 6PGD_CITDI ;
DR   P41583, 6PGD_CITFR ;  O60037, 6PGD_CUNEL ;  Q8TA03, 6PGD_DICDI ;
DR   P41572, 6PGD_DROME ;  P41573, 6PGD_DROSI ;  P00350, 6PGD_ECOLI ;
DR   P41574, 6PGD_ESCVU ;  Q7VMX4, 6PGD_HAEDU ;  P43774, 6PGD_HAEIN ;
DR   P52209, 6PGD_HUMAN ;  P41576, 6PGD_KLEPN ;  Q9CHU6, 6PGD_LACLA ;
DR   P96789, 6PGD_LACLM ;  Q9DCD0, 6PGD_MOUSE ;  P14332, 6PGD_PIG   ;
DR   P41575, 6PGD_RAOPL ;  P41577, 6PGD_RAOTE ;  P85968, 6PGD_RAT   ;
DR   P14062, 6PGD_SALTY ;  P78812, 6PGD_SCHPO ;  P00349, 6PGD_SHEEP ;
DR   P41578, 6PGD_SHIBO ;  P41579, 6PGD_SHIDY ;  P37756, 6PGD_SHIFL ;
DR   P41580, 6PGD_SHISO ;  Q5HFR2, 6PGD_STAAC ;  Q931R3, 6PGD_STAAM ;
DR   P63334, 6PGD_STAAN ;  Q6GGI7, 6PGD_STAAR ;  Q6G954, 6PGD_STAAS ;
DR   P63335, 6PGD_STAAW ;  Q5HP42, 6PGD_STAEQ ;  Q8CP47, 6PGD_STAES ;
DR   P21577, 6PGD_SYNE7 ;  P52208, 6PGD_SYNY3 ;  O83351, 6PGD_TREPA ;
DR   P31072, 6PGD_TRYBB ;
//
ID   1.1.1.45
DE   L-gulonate 3-dehydrogenase.
AN   L-3-aldonate dehydrogenase.
CA   L-gulonate + NAD(+) = 3-dehydro-L-gulonate + NADH.
CC   -!- Also oxidizes other L-3-hydroxyacids.
DR   Q8SPX7, CRYL1_BOVIN;  Q9Y2S2, CRYL1_HUMAN;  Q99KP3, CRYL1_MOUSE;
DR   Q8SQ26, CRYL1_PIG  ;  Q5RDZ2, CRYL1_PONAB;  P14755, CRYL1_RABIT;
DR   Q811X6, CRYL1_RAT  ;
//
ID   1.1.1.46
DE   L-arabinose 1-dehydrogenase.
CA   L-arabinose + NAD(+) = L-arabinono-1,4-lactone + NADH.
//
ID   1.1.1.47
DE   Glucose 1-dehydrogenase.
CA   Beta-D-glucose + NAD(P)(+) = D-glucono-1,5-lactone + NAD(P)H.
CC   -!- Also oxidizes D-xylose.
PR   PROSITE; PDOC00060;
PR   PROSITE; PDOC00067;
DR   P39482, DHG1_BACME ;  P39483, DHG2_BACME ;  P80869, DHG2_BACSU ;
DR   P39484, DHG3_BACME ;  P39485, DHG4_BACME ;  P10528, DHGA_BACME ;
DR   P07999, DHGB_BACME ;  P40288, DHG_BACME  ;  P12310, DHG_BACSU  ;
DR   P13203, DHG_THEAC  ;  O95479, G6PE_HUMAN ;  Q8CFX1, G6PE_MOUSE ;
DR   P56201, G6PE_RABIT ;
//
ID   1.1.1.48
DE   Galactose 1-dehydrogenase.
AN   D-galactose 1-dehydrogenase.
CA   D-galactose + NAD(+) = D-galactono-1,4-lactone + NADH.
DR   P11886, GAL_PSEFL  ;
//
ID   1.1.1.49
DE   Glucose-6-phosphate dehydrogenase.
AN   G6PD.
AN   G6PDH.
AN   Glucose-6-phosphate 1-dehydrogenase.
AN   GPD.
CA   D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone +
CA   NADPH.
CC   -!- Also acts slowly on beta-D-glucose and other sugars.
CC   -!- Certain preparations reduce NAD(+) as well as NADP(+).
PR   PROSITE; PDOC00067;
DR   Q43727, G6PD1_ARATH;  Q00612, G6PD1_MOUSE;  Q9FY99, G6PD2_ARATH;
DR   P97324, G6PD2_MOUSE;  P0A587, G6PD2_MYCBO;  P0A586, G6PD2_MYCTU;
DR   O59812, G6PD2_SCHPO;  Q8L743, G6PD3_ARATH;  O14137, G6PD3_SCHPO;
DR   Q93ZW0, G6PD4_ARATH;  Q9LK23, G6PD5_ARATH;  Q9FJI5, G6PD6_ARATH;
DR   Q43839, G6PDC_SOLTU;  O24357, G6PDC_SPIOL;  Q43793, G6PDC_TOBAC;
DR   P77809, G6PD_AGGAC ;  P48826, G6PD_ASPNG ;  P54547, G6PD_BACSU ;
DR   O51581, G6PD_BORBU ;  Q7YS37, G6PD_BOSIN ;  P57405, G6PD_BUCAI ;
DR   Q8K9M2, G6PD_BUCAP ;  Q89AI7, G6PD_BUCBP ;  Q27464, G6PD_CAEEL ;
DR   P41571, G6PD_CERCA ;  Q9PKK8, G6PD_CHLMU ;  Q9Z8U6, G6PD_CHLPN ;
DR   O84188, G6PD_CHLTR ;  O55044, G6PD_CRIGR ;  Q23711, G6PD_CULPI ;
DR   P11410, G6PD_CYBJA ;  P37986, G6PD_DICD3 ;  Q557D2, G6PD_DICDI ;
DR   P15588, G6PD_DIDMA ;  P12646, G6PD_DROME ;  Q24625, G6PD_DROSI ;
DR   Q27638, G6PD_DROYA ;  Q8XCJ6, G6PD_ECO57 ;  P0AC54, G6PD_ECOL6 ;
DR   P0AC53, G6PD_ECOLI ;  P41764, G6PD_EMENI ;  Q8SR89, G6PD_ENCCU ;
DR   P44311, G6PD_HAEIN ;  Q9ZKB2, G6PD_HELPJ ;  P56110, G6PD_HELPY ;
DR   P11413, G6PD_HUMAN ;  Q25019, G6PD_HYACE ;  P48828, G6PD_KLULA ;
DR   P11411, G6PD_LEUME ;  Q29492, G6PD_MACRO ;  P80619, G6PD_MAIZE ;
DR   Q42919, G6PD_MEDSA ;  P0A585, G6PD_MYCBO ;  A0QP90, G6PD_MYCS2 ;
DR   P0A584, G6PD_MYCTU ;  P48848, G6PD_NOSP7 ;  P48992, G6PD_NOSS1 ;
DR   O68282, G6PD_PSEAE ;  P05370, G6PD_RAT   ;  Q9Z3S2, G6PD_RHIME ;
DR   Q25537, G6PD_SARBU ;  O00091, G6PD_SCHPO ;  P37830, G6PD_SOLTU ;
DR   O54537, G6PD_STRPN ;  P29686, G6PD_SYNE7 ;  P73411, G6PD_SYNY3 ;
DR   P54996, G6PD_TAKRU ;  Q9X0N9, G6PD_THEMA ;  O83491, G6PD_TREPA ;
DR   P11412, G6PD_YEAST ;  P21907, G6PD_ZYMMO ;
//
ID   1.1.1.50
DE   3-alpha-hydroxysteroid dehydrogenase (B-specific).
AN   3-alpha-HSD.
AN   Hydroxyprostaglandin dehydrogenase.
CA   Androsterone + NAD(P)(+) = 5-alpha-androstane-3,17-dione + NAD(P)H.
CC   -!- Acts on other 3-alpha-hydroxysteroids and on 9-, 11- and
CC       15-hydroxyprostaglandin.
CC   -!- B-specific with respect to NAD(+) or NADP(+) (cf. EC 1.1.1.213).
PR   PROSITE; PDOC00061;
DR   P17516, AK1C4_HUMAN;  Q95JH5, AK1C4_MACFA;  Q95JH4, AK1C4_MACFU;
DR   P80702, DIDH_COMTE ;  P80701, DIDH_PSESP ;
//
ID   1.1.1.51
DE   3(or 17)-beta-hydroxysteroid dehydrogenase.
CA   Testosterone + NAD(P)(+) = androst-4-ene-3,17-dione + NAD(P)H.
CC   -!- Also acts on other 3-beta- or 17-beta-hydroxysteroids (cf.
CC       EC 1.1.1.209).
PR   PROSITE; PDOC00060;
DR   P19871, 3BHD_COMTE ;
//
ID   1.1.1.52
DE   3-alpha-hydroxycholanate dehydrogenase.
CA   3-alpha-hydroxy-5-beta-cholanate + NAD(+) = 3-oxo-5-beta-cholanate +
CA   NADH.
CC   -!- Also acts on other 3-alpha-hydroxysteroids with an acidic side-chain.
//
ID   1.1.1.53
DE   3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase.
AN   (R)-20-hydroxysteroid dehydrogenase.
AN   Cortisone reductase.
CA   Androstan-3-alpha,17-beta-diol + NAD(+) = 17-beta-hydroxyandrostan-3-one
CA   + NADH.
CC   -!- The 3-alpha-hydroxy group or 20-beta-hydroxy group of pregnane and
CC       androstane steroids can act as donor.
PR   PROSITE; PDOC00060;
DR   P69166, HSD_MYCBO  ;  P69167, HSD_MYCTU  ;  P19992, HSD_STREX  ;
//
ID   1.1.1.54
DE   Allyl-alcohol dehydrogenase.
CA   Allyl alcohol + NADP(+) = acrolein + NADPH.
CC   -!- Also acts on saturated primary alcohols.
//
ID   1.1.1.55
DE   Lactaldehyde reductase (NADPH).
CA   Propane-1,2-diol + NADP(+) = L-lactaldehyde + NADPH.
CC   -!- May be identical with EC 1.1.1.2.
//
ID   1.1.1.56
DE   Ribitol 2-dehydrogenase.
CA   Ribitol + NAD(+) = D-ribulose + NADH.
PR   PROSITE; PDOC00060;
DR   P00335, RIDH_ENTAE ;
//
ID   1.1.1.57
DE   Fructuronate reductase.
AN   D-mannonate dehydrogenase.
AN   D-mannonate oxidoreductase.
AN   Mannonic dehydrogenase.
CA   D-mannonate + NAD(+) = D-fructuronate + NADH.
CC   -!- Also reduces D-tagaturonate.
PR   PROSITE; PDOC00751;
DR   P39160, UXUB_ECOLI ;
//
ID   1.1.1.58
DE   Tagaturonate reductase.
AN   Altronate dehydrogenase.
AN   Altronate oxidoreductase.
AN   Altronic oxidoreductase.
AN   Tagaturonate dehydrogenase.
CA   D-altronate + NAD(+) = D-tagaturonate + NADH.
DR   Q9KFI7, UXAB_BACHD ;  O34354, UXAB_BACSU ;  Q8A9J0, UXAB_BACTN ;
DR   A6L4U5, UXAB_BACV8 ;  A8AGR0, UXAB_CITK8 ;  Q97L67, UXAB_CLOAB ;
DR   A7ZLX7, UXAB_ECO24 ;  B7URP8, UXAB_ECO27 ;  B7MMY5, UXAB_ECO45 ;
DR   B7L7M1, UXAB_ECO55 ;  P0A6L8, UXAB_ECO57 ;  B5Z1X8, UXAB_ECO5E ;
DR   B7NIJ4, UXAB_ECO7I ;  B7LZC3, UXAB_ECO8A ;  C4ZWT8, UXAB_ECOBW ;
DR   A8A074, UXAB_ECOHS ;  A1ABA1, UXAB_ECOK1 ;  Q0THR7, UXAB_ECOL5 ;
DR   B1IRT9, UXAB_ECOLC ;  P0A6L7, UXAB_ECOLI ;  B7N4U6, UXAB_ECOLU ;
DR   B6IAS4, UXAB_ECOSE ;  B1LF94, UXAB_ECOSM ;  Q1RBP6, UXAB_ECOUT ;
DR   A4WAF9, UXAB_ENT38 ;  A7MPR2, UXAB_ENTS8 ;  Q6D9G9, UXAB_ERWCT ;
DR   B7LRD0, UXAB_ESCF3 ;  B5XQU5, UXAB_KLEP3 ;  A6T900, UXAB_KLEP7 ;
DR   C6DKE8, UXAB_PECCP ;  Q0T4K8, UXAB_SHIF8 ;  Q83RE1, UXAB_SHIFL ;
DR   Q3Z1Q7, UXAB_SHISS ;  A1JR24, UXAB_YERE8 ;  Q8ZIC5, UXAB_YERPE ;
DR   Q1CMJ9, UXAB_YERPN ;  A4THM0, UXAB_YERPP ;
//
ID   1.1.1.59
DE   3-hydroxypropionate dehydrogenase.
CA   3-hydroxypropanoate + NAD(+) = 3-oxopropanoate + NADH.
//
ID   1.1.1.60
DE   2-hydroxy-3-oxopropionate reductase.
AN   Tartronate semialdehyde reductase.
CA   (R)-glycerate + NAD(P)(+) = 2-hydroxy-3-oxopropanoate + NAD(P)H.
DR   P0ABQ3, GARR_ECOL6 ;  P0ABQ2, GARR_ECOLI ;  P77161, GLXR_ECOLI ;
//
ID   1.1.1.61
DE   4-hydroxybutyrate dehydrogenase.
CA   4-hydroxybutanoate + NAD(+) = succinate semialdehyde + NADH.
PR   PROSITE; PDOC00059;
DR   P38945, 4HDB_CLOK5 ;
//
ID   1.1.1.62
DE   Estradiol 17-beta-dehydrogenase.
AN   17-beta-estradiol dehydrogenase.
AN   17-beta-HSD.
AN   17-beta-hydroxysteroid dehydrogenase.
AN   20-alpha-hydroxysteroid dehydrogenase.
AN   Estrogen 17-oxidoreductase.
CA   Estradiol-17-beta + NAD(P)(+) = estrone + NAD(P)H.
CC   -!- Also acts on (S)-20-hydroxypregn-4-en-3-one and related compounds,
CC       oxidizing the (S)-20-group.
CC   -!- B-specific with respect to NAD(P)(+) (cf. EC 1.1.1.149).
PR   PROSITE; PDOC00060;
DR   Q6P3L6, DH12A_DANRE;  Q5XG41, DH12A_XENLA;  Q6QA33, DH12B_DANRE;
DR   Q8AVY8, DH12B_XENLA;  Q8NBQ5, DHB11_HUMAN;  Q4JK73, DHB11_MACFA;
DR   Q9EQ06, DHB11_MOUSE;  Q5NVG2, DHB11_PONAB;  O57314, DHB12_ANAPL;
DR   Q5E9H7, DHB12_BOVIN;  Q53GQ0, DHB12_HUMAN;  Q4R5G7, DHB12_MACFA;
DR   O70503, DHB12_MOUSE;  Q6P7R8, DHB12_RAT  ;  Q28IU1, DHB12_XENTR;
DR   P14061, DHB1_HUMAN ;  P51656, DHB1_MOUSE ;  Q1WNP0, DHB1_PANTR ;
DR   P51657, DHB1_RAT   ;  P37059, DHB2_HUMAN ;  P51658, DHB2_MOUSE ;
DR   Q62730, DHB2_RAT   ;  P56937, DHB7_HUMAN ;  O88736, DHB7_MOUSE ;
DR   Q62904, DHB7_RAT   ;  Q9GME3, DHB8_CALJA ;  Q5TJF5, DHB8_CANFA ;
DR   Q92506, DHB8_HUMAN ;  P50171, DHB8_MOUSE ;  Q9XT00, DHB8_PIG   ;
DR   Q6MGB5, DHB8_RAT   ;  Q3T001, H17B6_BOVIN;  O14756, H17B6_HUMAN;
DR   Q9R092, H17B6_MOUSE;  O54753, H17B6_RAT  ;
//
ID   1.1.1.63
DE   Testosterone 17-beta-dehydrogenase.
AN   17-beta-HSD.
AN   17-ketoreductase.
CA   Testosterone + NAD(+) = androst-4-ene-3,17-dione + NADH.
DR   P42330, AK1C3_HUMAN;  Q5R7C9, AK1C3_PONAB;  P37059, DHB2_HUMAN ;
DR   P51658, DHB2_MOUSE ;  Q62730, DHB2_RAT   ;  Q9GME3, DHB8_CALJA ;
DR   Q5TJF5, DHB8_CANFA ;  Q92506, DHB8_HUMAN ;  P50171, DHB8_MOUSE ;
DR   Q9XT00, DHB8_PIG   ;  Q6MGB5, DHB8_RAT   ;  Q3T001, H17B6_BOVIN;
DR   O14756, H17B6_HUMAN;  Q9R092, H17B6_MOUSE;  O54753, H17B6_RAT  ;
//
ID   1.1.1.64
DE   Testosterone 17-beta-dehydrogenase (NADP(+)).
AN   17-ketoreductase.
CA   Testosterone + NADP(+) = androst-4-ene-3,17-dione + NADPH.
CC   -!- Also oxidizes 3-hydroxyhexobarbital to 3-oxohexobarbital.
DR   P42330, AK1C3_HUMAN;  Q5R7C9, AK1C3_PONAB;  P37058, DHB3_HUMAN ;
DR   P70385, DHB3_MOUSE ;  O54939, DHB3_RAT   ;
//
ID   1.1.1.65
DE   Pyridoxine 4-dehydrogenase.
AN   PL reductase.
AN   Pyridoxal reductase.
AN   Pyridoxin dehydrogenase.
AN   Pyridoxine dehydrogenase.
CA   Pyridoxine + NADP(+) = pyridoxal + NADPH.
CC   -!- Also oxidizes pyridoxine phosphate.
DR   O14295, PLR1_SCHPO ;  Q06494, PLR1_YEAST ;  O94521, PLR2_SCHPO ;
//
ID   1.1.1.66
DE   Omega-hydroxydecanoate dehydrogenase.
CA   10-hydroxydecanoate + NAD(+) = 10-oxodecanoate + NADH.
CC   -!- Also acts, more slowly, on 9-hydroxynonanoate and
CC       11-hydroxyundecanoate.
//
ID   1.1.1.67
DE   Mannitol 2-dehydrogenase.
AN   Mannitol dehydrogenase.
CA   D-mannitol + NAD(+) = D-fructose + NADH.
PR   PROSITE; PDOC00751;
DR   A1CLZ5, M2DH_ASPCL ;  B0Y581, M2DH_ASPFC ;  Q4WQY4, M2DH_ASPFU ;
DR   A2QGA1, M2DH_ASPNC ;  Q2U100, M2DH_ASPOR ;  Q0CYP4, M2DH_ASPTN ;
DR   Q5B9G5, M2DH_EMENI ;  A4QQN1, M2DH_MAGO7 ;  A1CVQ6, M2DH_NEOFI ;
DR   Q0UEB6, M2DH_PHANO ;  B2W2N2, M2DH_PYRTR ;  P33216, MTLK_RHOSH ;
//
ID   1.1.1.68
DE   Transferred entry: 1.5.1.20.
//
ID   1.1.1.69
DE   Gluconate 5-dehydrogenase.
AN   5-keto-D-gluconate 5-reductase.
AN   5-ketogluconate 5-reductase.
AN   5-ketogluconate reductase.
CA   D-gluconate + NAD(P)(+) = 5-dehydro-D-gluconate + NAD(P)H.
PR   PROSITE; PDOC00060;
DR   P50199, GNO_GLUOX  ;  P0A9Q0, IDNO_ECOL6 ;  P0A9P9, IDNO_ECOLI ;
//
ID   1.1.1.70
DE   Transferred entry: 1.2.1.3.
//
ID   1.1.1.71
DE   Alcohol dehydrogenase (NAD(P)(+)).
AN   Retinal reductase.
CA   An alcohol + NAD(P)(+) = an aldehyde + NAD(P)H.
CC   -!- Reduces aliphatic aldehydes of chain length from C2 to C14, with
CC       greatest activity on C4, C6 and C8 aldehydes.
CC   -!- Also reduces retinal to retinol.
//
ID   1.1.1.72
DE   Glycerol dehydrogenase (NADP(+)).
CA   Glycerol + NADP(+) = D-glyceraldehyde + NADPH.
PR   PROSITE; PDOC00061;
DR   P55804, DHGP_ASPNG ;
//
ID   1.1.1.73
DE   Octanol dehydrogenase.
CA   1-octanol + NAD(+) = 1-octanal + NADH.
CC   -!- Acts, less rapidly, on other long-chain alcohols.
PR   PROSITE; PDOC00058;
DR   P46415, ADHX_DROME ;
//
ID   1.1.1.74
DE   Deleted entry.
//
ID   1.1.1.75
DE   (R)-aminopropanol dehydrogenase.
CA   (R)-1-aminopropan-2-ol + NAD(+) = aminoacetone + NADH.
CF   Potassium.
//
ID   1.1.1.76
DE   (S,S)-butanediol dehydrogenase.
CA   (2S,3S)-butane-2,3-diol + NAD(+) = (S)-acetoin + NADH.
CC   -!- This enzyme catalyzes the reversible reduction of (S)-acetoin to
CC       (S,S)-butane-2,3-diol.
CC   -!- It can also catalyze the irreversible reduction of diacetyl to (S)-
CC       acetoin.
PR   PROSITE; PDOC00060;
//
ID   1.1.1.77
DE   Lactaldehyde reductase.
AN   Propanediol oxidoreductase.
CA   (1) (R)-propane-1,2-diol + NAD(+) = (R)-lactaldehyde + NADH.
CA   (2) (S)-propane-1,2-diol + NAD(+) = (S)-lactaldehyde + NADH.
PR   PROSITE; PDOC00059;
DR   P0A9S2, FUCO_ECO57 ;  P0A9S1, FUCO_ECOLI ;
//
ID   1.1.1.78
DE   Methylglyoxal reductase (NADH-dependent).
AN   D-lactaldehyde dehydrogenase.
AN   Methylglyoxal reductase.
CA   (R)-lactaldehyde + NAD(+) = methylglyoxal + NADH.
CC   -!- This mammalian enzyme differs from the yeast enzyme, EC 1.1.1.283,
CC       in using NADH rather than NADPH as reductant.
CC   -!- It oxidizes HO-CH(2)-CHOH-CHO (glyceraldehyde) as well as CH(3)-CHOH-
CC       CHO (lactaldehyde).
PR   PROSITE; PDOC00061;
//
ID   1.1.1.79
DE   Glyoxylate reductase (NADP(+)).
CA   Glycolate + NADP(+) = glyoxylate + NADPH.
CC   -!- Also reduces hydroxypyruvate to glycerate.
CC   -!- Has some affinity for NAD(+).
DR   A8AI49, GHRA_CITK8 ;  B7UP47, GHRA_ECO27 ;  B7MIH3, GHRA_ECO45 ;
DR   B7LFE3, GHRA_ECO55 ;  Q8X9K1, GHRA_ECO57 ;  B5YVQ3, GHRA_ECO5E ;
DR   B7NLA1, GHRA_ECO7I ;  B7MTG4, GHRA_ECO81 ;  B7M907, GHRA_ECO8A ;
DR   C4ZRX4, GHRA_ECOBW ;  B1X9E7, GHRA_ECODH ;  A7ZYY6, GHRA_ECOHS ;
DR   A1A9T1, GHRA_ECOK1 ;  Q0TJ41, GHRA_ECOL5 ;  Q8FIT1, GHRA_ECOL6 ;
DR   B1IV68, GHRA_ECOLC ;  P75913, GHRA_ECOLI ;  B7N3I0, GHRA_ECOLU ;
DR   B6I9A9, GHRA_ECOSE ;  B1LIY1, GHRA_ECOSM ;  Q1RDC8, GHRA_ECOUT ;
DR   A4W948, GHRA_ENT38 ;  A7MFZ8, GHRA_ENTS8 ;  B7LTA2, GHRA_ESCF3 ;
DR   B5XXL3, GHRA_KLEP3 ;  A6T7B8, GHRA_KLEP7 ;  Q7N571, GHRA_PHOLL ;
DR   B5F974, GHRA_SALA4 ;  A9MH27, GHRA_SALAR ;  Q57QM2, GHRA_SALCH ;
DR   B5FL30, GHRA_SALDC ;  B5QY30, GHRA_SALEP ;  B5RBG3, GHRA_SALG2 ;
DR   B4TEQ6, GHRA_SALHS ;  B4T2W6, GHRA_SALNS ;  Q5PGZ3, GHRA_SALPA ;
DR   A9N5T3, GHRA_SALPB ;  C0Q872, GHRA_SALPC ;  B5BBF3, GHRA_SALPK ;
DR   B4TSP5, GHRA_SALSV ;  Q8Z7M6, GHRA_SALTI ;  Q8ZQ30, GHRA_SALTY ;
DR   A8GD46, GHRA_SERP5 ;  B2TTN6, GHRA_SHIB3 ;  Q31Z89, GHRA_SHIBS ;
DR   Q32HN5, GHRA_SHIDS ;  Q3Z393, GHRA_SHISS ;  A1JRR3, GHRA_YERE8 ;
DR   A8ARD9, GHRB_CITK8 ;  A7ZTA0, GHRB_ECO24 ;  B7ULB4, GHRB_ECO27 ;
DR   B7MER0, GHRB_ECO45 ;  B7L6W9, GHRB_ECO55 ;  P58220, GHRB_ECO57 ;
DR   B5YVK6, GHRB_ECO5E ;  B7NP49, GHRB_ECO7I ;  B7N1K7, GHRB_ECO81 ;
DR   B7M3H6, GHRB_ECO8A ;  C4ZXE2, GHRB_ECOBW ;  B1X8G8, GHRB_ECODH ;
DR   A8A609, GHRB_ECOHS ;  A1AH96, GHRB_ECOK1 ;  Q0TBP9, GHRB_ECOL5 ;
DR   Q8FCF1, GHRB_ECOL6 ;  B1IZP1, GHRB_ECOLC ;  P37666, GHRB_ECOLI ;
DR   B7NEK6, GHRB_ECOLU ;  B6I3C3, GHRB_ECOSE ;  B1LJB3, GHRB_ECOSM ;
DR   Q1R543, GHRB_ECOUT ;  A4W577, GHRB_ENT38 ;  P58000, GHRB_ENTAG ;
DR   A7MKR1, GHRB_ENTS8 ;  Q6DB24, GHRB_ERWCT ;  B2VCD1, GHRB_ERWT9 ;
DR   B7LTG7, GHRB_ESCF3 ;  B5XMZ4, GHRB_KLEP3 ;  A6TFG7, GHRB_KLEP7 ;
DR   C6DJ88, GHRB_PECCP ;  B5EX58, GHRB_SALA4 ;  Q57IH8, GHRB_SALCH ;
DR   B5FLC2, GHRB_SALDC ;  B5R4N3, GHRB_SALEP ;  B5RGN1, GHRB_SALG2 ;
DR   B4T938, GHRB_SALHS ;  B4SWJ5, GHRB_SALNS ;  Q5PLL9, GHRB_SALPA ;
DR   A9MUT4, GHRB_SALPB ;  C0Q1A7, GHRB_SALPC ;  B5BHT3, GHRB_SALPK ;
DR   B4TZ41, GHRB_SALSV ;  Q8Z2A8, GHRB_SALTI ;  Q8ZLA1, GHRB_SALTY ;
DR   A8G7S7, GHRB_SERP5 ;  B2U573, GHRB_SHIB3 ;  Q31V71, GHRB_SHIBS ;
DR   Q328L4, GHRB_SHIDS ;  Q0SZE5, GHRB_SHIF8 ;  Q83PR3, GHRB_SHIFL ;
DR   Q3YVT5, GHRB_SHISS ;  A1JT62, GHRB_YERE8 ;  A7FPA2, GHRB_YERP3 ;
DR   Q1C3K4, GHRB_YERPA ;  B2K7F1, GHRB_YERPB ;  Q0W9V5, GHRB_YERPE ;
DR   A9R4G6, GHRB_YERPG ;  Q1CD80, GHRB_YERPN ;  A4TGN1, GHRB_YERPP ;
DR   Q663W4, GHRB_YERPS ;  B1JH01, GHRB_YERPY ;  Q9UBQ7, GRHPR_HUMAN;
DR   Q91Z53, GRHPR_MOUSE;
//
ID   1.1.1.80
DE   Isopropanol dehydrogenase (NADP(+)).
CA   Propan-2-ol + NADP(+) = acetone + NADPH.
CC   -!- Also acts on other short-chain secondary alcohols and, slowly,
CC       on primary alcohols.
//
ID   1.1.1.81
DE   Hydroxypyruvate reductase.
AN   D-glycerate dehydrogenase.
CA   D-glycerate + NAD(P)(+) = hydroxypyruvate + NAD(P)H.
DR   A8AI49, GHRA_CITK8 ;  B7UP47, GHRA_ECO27 ;  B7MIH3, GHRA_ECO45 ;
DR   B7LFE3, GHRA_ECO55 ;  Q8X9K1, GHRA_ECO57 ;  B5YVQ3, GHRA_ECO5E ;
DR   B7NLA1, GHRA_ECO7I ;  B7MTG4, GHRA_ECO81 ;  B7M907, GHRA_ECO8A ;
DR   C4ZRX4, GHRA_ECOBW ;  B1X9E7, GHRA_ECODH ;  A7ZYY6, GHRA_ECOHS ;
DR   A1A9T1, GHRA_ECOK1 ;  Q0TJ41, GHRA_ECOL5 ;  Q8FIT1, GHRA_ECOL6 ;
DR   B1IV68, GHRA_ECOLC ;  P75913, GHRA_ECOLI ;  B7N3I0, GHRA_ECOLU ;
DR   B6I9A9, GHRA_ECOSE ;  B1LIY1, GHRA_ECOSM ;  Q1RDC8, GHRA_ECOUT ;
DR   A4W948, GHRA_ENT38 ;  A7MFZ8, GHRA_ENTS8 ;  B7LTA2, GHRA_ESCF3 ;
DR   B5XXL3, GHRA_KLEP3 ;  A6T7B8, GHRA_KLEP7 ;  Q7N571, GHRA_PHOLL ;
DR   B5F974, GHRA_SALA4 ;  A9MH27, GHRA_SALAR ;  Q57QM2, GHRA_SALCH ;
DR   B5FL30, GHRA_SALDC ;  B5QY30, GHRA_SALEP ;  B5RBG3, GHRA_SALG2 ;
DR   B4TEQ6, GHRA_SALHS ;  B4T2W6, GHRA_SALNS ;  Q5PGZ3, GHRA_SALPA ;
DR   A9N5T3, GHRA_SALPB ;  C0Q872, GHRA_SALPC ;  B5BBF3, GHRA_SALPK ;
DR   B4TSP5, GHRA_SALSV ;  Q8Z7M6, GHRA_SALTI ;  Q8ZQ30, GHRA_SALTY ;
DR   A8GD46, GHRA_SERP5 ;  B2TTN6, GHRA_SHIB3 ;  Q31Z89, GHRA_SHIBS ;
DR   Q32HN5, GHRA_SHIDS ;  Q3Z393, GHRA_SHISS ;  A1JRR3, GHRA_YERE8 ;
DR   A8ARD9, GHRB_CITK8 ;  A7ZTA0, GHRB_ECO24 ;  B7ULB4, GHRB_ECO27 ;
DR   B7MER0, GHRB_ECO45 ;  B7L6W9, GHRB_ECO55 ;  P58220, GHRB_ECO57 ;
DR   B5YVK6, GHRB_ECO5E ;  B7NP49, GHRB_ECO7I ;  B7N1K7, GHRB_ECO81 ;
DR   B7M3H6, GHRB_ECO8A ;  C4ZXE2, GHRB_ECOBW ;  B1X8G8, GHRB_ECODH ;
DR   A8A609, GHRB_ECOHS ;  A1AH96, GHRB_ECOK1 ;  Q0TBP9, GHRB_ECOL5 ;
DR   Q8FCF1, GHRB_ECOL6 ;  B1IZP1, GHRB_ECOLC ;  P37666, GHRB_ECOLI ;
DR   B7NEK6, GHRB_ECOLU ;  B6I3C3, GHRB_ECOSE ;  B1LJB3, GHRB_ECOSM ;
DR   Q1R543, GHRB_ECOUT ;  A4W577, GHRB_ENT38 ;  P58000, GHRB_ENTAG ;
DR   A7MKR1, GHRB_ENTS8 ;  Q6DB24, GHRB_ERWCT ;  B2VCD1, GHRB_ERWT9 ;
DR   B7LTG7, GHRB_ESCF3 ;  B5XMZ4, GHRB_KLEP3 ;  A6TFG7, GHRB_KLEP7 ;
DR   C6DJ88, GHRB_PECCP ;  B5EX58, GHRB_SALA4 ;  Q57IH8, GHRB_SALCH ;
DR   B5FLC2, GHRB_SALDC ;  B5R4N3, GHRB_SALEP ;  B5RGN1, GHRB_SALG2 ;
DR   B4T938, GHRB_SALHS ;  B4SWJ5, GHRB_SALNS ;  Q5PLL9, GHRB_SALPA ;
DR   A9MUT4, GHRB_SALPB ;  C0Q1A7, GHRB_SALPC ;  B5BHT3, GHRB_SALPK ;
DR   B4TZ41, GHRB_SALSV ;  Q8Z2A8, GHRB_SALTI ;  Q8ZLA1, GHRB_SALTY ;
DR   A8G7S7, GHRB_SERP5 ;  B2U573, GHRB_SHIB3 ;  Q31V71, GHRB_SHIBS ;
DR   Q328L4, GHRB_SHIDS ;  Q0SZE5, GHRB_SHIF8 ;  Q83PR3, GHRB_SHIFL ;
DR   Q3YVT5, GHRB_SHISS ;  A1JT62, GHRB_YERE8 ;  A7FPA2, GHRB_YERP3 ;
DR   Q1C3K4, GHRB_YERPA ;  B2K7F1, GHRB_YERPB ;  Q0W9V5, GHRB_YERPE ;
DR   A9R4G6, GHRB_YERPG ;  Q1CD80, GHRB_YERPN ;  A4TGN1, GHRB_YERPP ;
DR   Q663W4, GHRB_YERPS ;  B1JH01, GHRB_YERPY ;  Q9UBQ7, GRHPR_HUMAN;
DR   Q91Z53, GRHPR_MOUSE;  P70788, TTUD3_AGRVI;  Q44472, TTUD4_AGRVI;
//
ID   1.1.1.82
DE   Malate dehydrogenase (NADP(+)).
AN   NADP-linked malate dehydrogenase.
CA   (S)-malate + NADP(+) = oxaloacetate + NADPH.
CC   -!- Activated by light.
PR   PROSITE; PDOC00066;
DR   P17606, MDHP1_SORBI;  P37229, MDHP2_SORBI;  P46489, MDHP_FLABI ;
DR   P15719, MDHP_MAIZE ;  O48902, MDHP_MEDSA ;  Q05145, MDHP_MESCR ;
DR   P21528, MDHP_PEA   ;  P52426, MDHP_SPIOL ;  Q9YEA1, MDH_AERPE  ;
DR   P16142, MDH_METFV  ;  Q60176, MDH_METJA  ;
//
ID   1.1.1.83
DE   D-malate dehydrogenase (decarboxylating).
CA   (R)-malate + NAD(+) = pyruvate + CO(2) + NADH.
DR   P76251, DMLA_ECOLI ;  Q58130, LEU3_METJA ;  Q44471, TTUC1_AGRVI;
DR   P70787, TTUC2_AGRVI;  O34296, TTUC3_AGRVI;  P70792, TTUC4_AGRVI;
DR   O34295, TTUC5_AGRVI;  P42958, TTUC_BACSU ;  Q51945, TTUC_PSEPU ;
//
ID   1.1.1.84
DE   Dimethylmalate dehydrogenase.
CA   (R)-3,3-dimethylmalate + NAD(+) = 3-methyl-2-oxobutanoate + CO(2) + NADH.
CF   Cobalt or manganese; Potassium or NH(4)(+).
CC   -!- Also acts on (R)-malate.
//
ID   1.1.1.85
DE   3-isopropylmalate dehydrogenase.
AN   Beta-IPM dehydrogenase.
AN   Beta-isopropylmalate dehydrogenase.
AN   IMDH.
CA   (2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO(2) +
CA   NADH.
CC   -!- The product decarboxylates spontaneously to yield 4-methyl-2-
CC       oxopentanoate.
PR   PROSITE; PDOC00389;
DR   Q9SA14, LEU31_ARATH;  Q7WNM3, LEU31_BORBR;  Q89XA0, LEU31_BRAJA;
DR   Q47HR1, LEU31_DECAR;  P93832, LEU32_ARATH;  Q7WKH4, LEU32_BORBR;
DR   Q89X19, LEU32_BRAJA;  Q479H7, LEU32_DECAR;  Q9FMT1, LEU33_ARATH;
DR   P87256, LEU3A_ASPNG;  P87257, LEU3B_ASPNG;  Q6FEV6, LEU3_ACIAD ;
DR   P24404, LEU3_AGRT5 ;  Q2IJK7, LEU3_ANADE ;  Q3M8T9, LEU3_ANAVT ;
DR   O66607, LEU3_AQUAE ;  O29627, LEU3_ARCFU ;  Q5P1J6, LEU3_AROAE ;
DR   O60027, LEU3_ASHGO ;  P96197, LEU3_AZOVI ;  Q81T67, LEU3_BACAN ;
DR   Q73B99, LEU3_BACC1 ;  P05644, LEU3_BACCA ;  P12010, LEU3_BACCO ;
DR   Q81G11, LEU3_BACCR ;  Q63DX7, LEU3_BACCZ ;  Q5LAB4, LEU3_BACFN ;
DR   P54354, LEU3_BACFR ;  Q9K8E9, LEU3_BACHD ;  Q6HLF2, LEU3_BACHK ;
DR   Q65GI9, LEU3_BACLD ;  P41019, LEU3_BACMD ;  Q5WEN4, LEU3_BACSK ;
DR   P05645, LEU3_BACSU ;  Q8A6M0, LEU3_BACTN ;  C5C2I9, LEU3_BEUC1 ;
DR   B3DTF8, LEU3_BIFLD ;  Q8G500, LEU3_BIFLO ;  B7GUI8, LEU3_BIFLS ;
DR   Q8NKB8, LEU3_BLAAD ;  Q7VQJ7, LEU3_BLOFL ;  Q493R1, LEU3_BLOPB ;
DR   Q2KYL5, LEU3_BORA1 ;  Q7W929, LEU3_BORPA ;  Q7VY73, LEU3_BORPE ;
DR   P29102, LEU3_BRANA ;  Q2YL58, LEU3_BRUA2 ;  Q579B1, LEU3_BRUAB ;
DR   Q8YCX4, LEU3_BRUME ;  Q8FVF3, LEU3_BRUSU ;  P56933, LEU3_BUCAI ;
DR   O85064, LEU3_BUCAP ;  P59515, LEU3_BUCBP ;  Q5WPZ9, LEU3_BUCCC ;
DR   O85071, LEU3_BUCDN ;  Q9EVG3, LEU3_BUCML ;  P59027, LEU3_BUCPS ;
DR   P48572, LEU3_BUCRP ;  O31292, LEU3_BUCTS ;  Q9EVG6, LEU3_BUCUA ;
DR   Q9EVE1, LEU3_BUCUD ;  Q9EVH5, LEU3_BUCUE ;  Q9EVH8, LEU3_BUCUH ;
DR   Q9AQC8, LEU3_BUCUL ;  Q9EVG9, LEU3_BUCUM ;  Q9EVI7, LEU3_BUCUN ;
DR   Q9EVI1, LEU3_BUCUO ;  Q9EVI4, LEU3_BUCUS ;  Q845W3, LEU3_BURM1 ;
DR   Q62AI9, LEU3_BURMA ;  Q3JKG9, LEU3_BURP1 ;  Q63JL2, LEU3_BURPS ;
DR   Q393X4, LEU3_BURS3 ;  Q2T7H6, LEU3_BURTA ;  Q9PLW0, LEU3_CAMJE ;
DR   Q5HS77, LEU3_CAMJR ;  P87186, LEU3_CANAL ;  Q01987, LEU3_CANBO ;
DR   O14429, LEU3_CANGA ;  P07139, LEU3_CANMA ;  Q6PY58, LEU3_CANMI ;
DR   Q9HDQ5, LEU3_CANRU ;  Q3AEQ2, LEU3_CARHZ ;  Q9ABN3, LEU3_CAUCR ;
DR   Q12545, LEU3_CEPAC ;  Q3APC4, LEU3_CHLCH ;  P59028, LEU3_CHLTE ;
DR   Q1QUR0, LEU3_CHRSD ;  Q7NUC2, LEU3_CHRVO ;  A5CPZ4, LEU3_CLAM3 ;
DR   B0RIP4, LEU3_CLAMS ;  Q97EE2, LEU3_CLOAB ;  P31958, LEU3_CLOPA ;
DR   Q47WG3, LEU3_COLP3 ;  C3PFX5, LEU3_CORA7 ;  Q6NHM7, LEU3_CORDI ;
DR   Q8FPV5, LEU3_COREF ;  A4QDP9, LEU3_CORGB ;  P94631, LEU3_CORGL ;
DR   Q4JUQ0, LEU3_CORJK ;  C4LJH3, LEU3_CORK4 ;  B1VG35, LEU3_CORU7 ;
DR   Q46YW0, LEU3_CUPPJ ;  P08791, LEU3_CYBJA ;  Q6B458, LEU3_DEBHA ;
DR   Q3Z896, LEU3_DEHE1 ;  Q3ZXI7, LEU3_DEHSC ;  Q1IZK2, LEU3_DEIGD ;
DR   Q9RTH9, LEU3_DEIRA ;  Q30WD0, LEU3_DESDG ;  Q24XT2, LEU3_DESHY ;
DR   Q6ANR1, LEU3_DESPS ;  Q726X1, LEU3_DESVH ;  Q8X9Z9, LEU3_ECO57 ;
DR   Q8FL76, LEU3_ECOL6 ;  P30125, LEU3_ECOLI ;  Q1RGC4, LEU3_ECOUT ;
DR   Q6D0G7, LEU3_ERWCT ;  Q2J6V8, LEU3_FRASC ;  A8L554, LEU3_FRASN ;
DR   Q5KWJ4, LEU3_GEOKA ;  Q39Y29, LEU3_GEOMG ;  Q748X2, LEU3_GEOSL ;
DR   Q7NFH4, LEU3_GLOVI ;  Q5FUG5, LEU3_GLUOX ;  Q4QLS3, LEU3_HAEI8 ;
DR   P43860, LEU3_HAEIN ;  Q2SJD6, LEU3_HAHCH ;  Q9HDQ1, LEU3_HANAN ;
DR   Q7VH33, LEU3_HELHP ;  Q28W67, LEU3_JANSC ;  P23390, LEU3_KLULA ;
DR   P41766, LEU3_KLUMA ;  P41926, LEU3_KODOH ;  Q02143, LEU3_LACLA ;
DR   Q6AEP6, LEU3_LEIXX ;  Q72RH7, LEU3_LEPIC ;  P24015, LEU3_LEPIN ;
DR   Q92A27, LEU3_LISIN ;  Q71Y34, LEU3_LISMF ;  Q8Y5R8, LEU3_LISMO ;
DR   Q2VZV2, LEU3_MAGSA ;  Q65V05, LEU3_MANSM ;  Q606F4, LEU3_METCA ;
DR   Q58130, LEU3_METJA ;  O27441, LEU3_METTH ;  Q2RGA0, LEU3_MOOTA ;
DR   A0QJC2, LEU3_MYCA1 ;  P94929, LEU3_MYCBO ;  A1KMY9, LEU3_MYCBP ;
DR   C1AGB0, LEU3_MYCBT ;  A4TE12, LEU3_MYCGI ;  Q9Y897, LEU3_MYCGR ;
DR   B8ZS15, LEU3_MYCLB ;  O33117, LEU3_MYCLE ;  B2HIH1, LEU3_MYCMM ;
DR   Q73VI1, LEU3_MYCPA ;  A3PXQ2, LEU3_MYCSJ ;  A1UE98, LEU3_MYCSK ;
DR   Q1BAR4, LEU3_MYCSS ;  A5U706, LEU3_MYCTA ;  P95313, LEU3_MYCTU ;
DR   A0PPY6, LEU3_MYCUA ;  A1T6Z4, LEU3_MYCVP ;  Q5F8T6, LEU3_NEIG1 ;
DR   P50180, LEU3_NEILA ;  Q9JU79, LEU3_NEIMA ;  Q9JZI9, LEU3_NEIMB ;
DR   P34738, LEU3_NEUCR ;  Q82WI6, LEU3_NITEU ;  Q2Y7Q8, LEU3_NITMU ;
DR   Q3JCC4, LEU3_NITOC ;  Q3SNU3, LEU3_NITWN ;  Q5YRX2, LEU3_NOCFA ;
DR   Q8YXA2, LEU3_NOSS1 ;  Q2G4X5, LEU3_NOVAD ;  Q8EN68, LEU3_OCEIH ;
DR   Q9CJN6, LEU3_PASMU ;  Q3A3B2, LEU3_PELCD ;  Q3B595, LEU3_PELLD ;
DR   Q4FP17, LEU3_PELUB ;  O59930, LEU3_PHACH ;  Q7N128, LEU3_PHOLL ;
DR   Q6LV25, LEU3_PHOPR ;  P34733, LEU3_PICAN ;  O94114, LEU3_PICST ;
DR   Q31B91, LEU3_PROM9 ;  Q7VC80, LEU3_PROMA ;  Q7V842, LEU3_PROMM ;
DR   Q7V1R9, LEU3_PROMP ;  Q46LE2, LEU3_PROMT ;  Q48K97, LEU3_PSE14 ;
DR   Q51375, LEU3_PSEAE ;  Q4KF05, LEU3_PSEF5 ;  Q3IJS3, LEU3_PSEHT ;
DR   Q3KF21, LEU3_PSEPF ;  Q88LE5, LEU3_PSEPK ;  Q884C0, LEU3_PSESM ;
DR   Q4ZUZ4, LEU3_PSEU2 ;  Q4FRV0, LEU3_PSYA2 ;  Q1QAF5, LEU3_PSYCK ;
DR   Q1LKH7, LEU3_RALME ;  Q8XXX5, LEU3_RALSO ;  Q2K2V0, LEU3_RHIEC ;
DR   Q1MA50, LEU3_RHIL3 ;  Q98E57, LEU3_RHILO ;  Q92KY8, LEU3_RHIME ;
DR   Q7UIE1, LEU3_RHOBA ;  C0ZXM4, LEU3_RHOE4 ;  Q21XI1, LEU3_RHOFD ;
DR   C1B2M3, LEU3_RHOOB ;  Q2J3B4, LEU3_RHOP2 ;  Q6ND82, LEU3_RHOPA ;
DR   Q21CS1, LEU3_RHOPB ;  Q2RV53, LEU3_RHORT ;  Q3IZJ3, LEU3_RHOS4 ;
DR   Q0S2H1, LEU3_RHOSR ;  Q21IY5, LEU3_SACD2 ;  A4FMQ2, LEU3_SACEN ;
DR   Q96WT9, LEU3_SACEX ;  Q57TE7, LEU3_SALCH ;  Q5PDG2, LEU3_SALPA ;
DR   Q2S0M8, LEU3_SALRD ;  Q8Z9I1, LEU3_SALTI ;  P37412, LEU3_SALTY ;
DR   P18869, LEU3_SCHPO ;  Q8E9N3, LEU3_SHEON ;  Q326G2, LEU3_SHIBS ;
DR   Q32K21, LEU3_SHIDS ;  Q83SP1, LEU3_SHIFL ;  Q3Z5T7, LEU3_SHISS ;
DR   Q5LWZ5, LEU3_SILPO ;  Q2NVW4, LEU3_SODGM ;  P29696, LEU3_SOLTU ;
DR   Q6TWC4, LEU3_SORMA ;  Q00412, LEU3_SPIPL ;  Q2FF66, LEU3_STAA3 ;
DR   Q2FWK2, LEU3_STAA8 ;  Q2YUF1, LEU3_STAAB ;  Q5HEE3, LEU3_STAAC ;
DR   P65100, LEU3_STAAM ;  P65101, LEU3_STAAN ;  Q6GF15, LEU3_STAAR ;
DR   Q6G7Q0, LEU3_STAAS ;  Q8NVJ0, LEU3_STAAW ;  Q5HMF8, LEU3_STAEQ ;
DR   Q8CNL2, LEU3_STAES ;  Q4L7U1, LEU3_STAHJ ;  Q49Z13, LEU3_STAS1 ;
DR   Q82JN6, LEU3_STRAW ;  O86504, LEU3_STRCO ;  B1VZ57, LEU3_STRGG ;
DR   Q8DTG3, LEU3_STRMU ;  Q8DPJ4, LEU3_STRR6 ;  Q5LZF3, LEU3_STRT1 ;
DR   Q5M405, LEU3_STRT2 ;  Q30RK2, LEU3_SULDN ;  Q9UXB2, LEU3_SULSO ;
DR   P50455, LEU3_SULTO ;  Q67JY2, LEU3_SYMTH ;  Q31N34, LEU3_SYNE7 ;
DR   Q2JTN8, LEU3_SYNJA ;  Q2JL30, LEU3_SYNJB ;  Q5MZ40, LEU3_SYNP6 ;
DR   Q7U840, LEU3_SYNPX ;  Q3AYS1, LEU3_SYNS9 ;  Q3AIH4, LEU3_SYNSC ;
DR   P73960, LEU3_SYNY3 ;  P24098, LEU3_THEAQ ;  P59029, LEU3_THEEB ;
DR   Q47SB4, LEU3_THEFY ;  Q9WZ26, LEU3_THEMA ;  P61494, LEU3_THET2 ;
DR   Q5SIY4, LEU3_THET8 ;  P61495, LEU3_THETH ;  Q8RDK0, LEU3_THETN ;
DR   Q31HI0, LEU3_THICR ;  Q3SHL3, LEU3_THIDA ;  Q56268, LEU3_THIFE ;
DR   Q9KP82, LEU3_VIBCH ;  Q5E857, LEU3_VIBF1 ;  Q87SS8, LEU3_VIBPA ;
DR   Q8DEE0, LEU3_VIBVU ;  Q7MP78, LEU3_VIBVY ;  Q7M886, LEU3_WOLSU ;
DR   Q8PH05, LEU3_XANAC ;  Q3BPJ8, LEU3_XANC5 ;  Q4UYG2, LEU3_XANC8 ;
DR   Q8P5L1, LEU3_XANCP ;  Q2P762, LEU3_XANOM ;  Q5H4C7, LEU3_XANOR ;
DR   Q9PAX3, LEU3_XYLFA ;  Q87BQ1, LEU3_XYLFT ;  P18120, LEU3_YARLI ;
DR   P04173, LEU3_YEAST ;  Q8ZIG9, LEU3_YERPE ;  Q66EM2, LEU3_YERPS ;
DR   Q9P3Y0, LEU3_ZYGBA ;  Q96WI0, LEU3_ZYGRC ;  Q5NPQ9, LEU3_ZYMMO ;
//
ID   1.1.1.86
DE   Ketol-acid reductoisomerase.
AN   Acetohydroxy acid isomeroreductase.
AN   Alpha-keto-beta-hydroxylacyl reductoisomerase.
AN   Dihydroxyisovalerate dehydrogenase (isomerizing).
CA   (1) (R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (S)-2-hydroxy-2-
CA   methyl-3-oxobutanoate + NADPH.
CA   (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-hydroxy-2-
CA   ethyl-3-oxobutanoate + NADPH.
CC   -!- Formerly EC 1.1.1.89.
DR   Q05758, ILV5_ARATH ;  P38674, ILV5_NEUCR ;  Q65XK0, ILV5_ORYSJ ;
DR   O82043, ILV5_PEA   ;  P84534, ILV5_POPEU ;  P78827, ILV5_SCHPO ;
DR   Q01292, ILV5_SPIOL ;  P06168, ILV5_YEAST ;  Q81T69, ILVC1_BACAN;
DR   Q73BA1, ILVC1_BACC1;  Q81G13, ILVC1_BACCR;  Q63DX9, ILVC1_BACCZ;
DR   Q6HLF4, ILVC1_BACHK;  Q8G6V2, ILVC1_BIFLO;  Q9Z565, ILVC1_STRCO;
DR   Q9UWX9, ILVC1_SULSO;  Q81S27, ILVC2_BACAN;  Q73A47, ILVC2_BACC1;
DR   Q81F27, ILVC2_BACCR;  Q63CV4, ILVC2_BACCZ;  Q6HKA1, ILVC2_BACHK;
DR   Q8G6V1, ILVC2_BIFLO;  Q9FBT8, ILVC2_STRCO;  Q97YJ9, ILVC2_SULSO;
DR   Q97X13, ILVC3_SULSO;  B0CE35, ILVC_ACAM1 ;  A1TRT6, ILVC_ACIAC ;
DR   Q6F821, ILVC_ACIAD ;  B7H047, ILVC_ACIB3 ;  B7I5I9, ILVC_ACIB5 ;
DR   B2HTC8, ILVC_ACIBC ;  Q1ILZ3, ILVC_ACIBL ;  B0VKP5, ILVC_ACIBS ;
DR   A3M254, ILVC_ACIBT ;  B0V5G8, ILVC_ACIBY ;  C1F6Z5, ILVC_ACIC5 ;
DR   A5G1L8, ILVC_ACICJ ;  B9MA35, ILVC_ACIET ;  B7J643, ILVC_ACIF2 ;
DR   B5EP52, ILVC_ACIF5 ;  A1W6T4, ILVC_ACISJ ;  A3N3E9, ILVC_ACTP2 ;
DR   B0BTD3, ILVC_ACTPJ ;  A6VLU1, ILVC_ACTSZ ;  A0KEM1, ILVC_AERHH ;
DR   A4STE2, ILVC_AERS4 ;  B9JGH5, ILVC_AGRRK ;  Q8UDV0, ILVC_AGRT5 ;
DR   B9JXM6, ILVC_AGRVS ;  B2URB8, ILVC_AKKM8 ;  Q0VSB5, ILVC_ALCBS ;
DR   Q0AB89, ILVC_ALHEH ;  B6EP33, ILVC_ALISL ;  A6TTL2, ILVC_ALKMQ ;
DR   B4S1X4, ILVC_ALTMD ;  B8J829, ILVC_ANAD2 ;  Q2IJB7, ILVC_ANADE ;
DR   B4UAN4, ILVC_ANASK ;  B9MNV1, ILVC_ANATD ;  Q3MGX7, ILVC_ANAVT ;
DR   B7GH18, ILVC_ANOFW ;  O67289, ILVC_AQUAE ;  A8ERD8, ILVC_ARCB4 ;
DR   O28294, ILVC_ARCFU ;  Q5NXP4, ILVC_AROAE ;  B8HAS8, ILVC_ARTCA ;
DR   A0JXZ6, ILVC_ARTS2 ;  A8I679, ILVC_AZOC5 ;  A1KAB7, ILVC_AZOSB ;
DR   C1DFH7, ILVC_AZOVD ;  A7Z7B9, ILVC_BACA2 ;  A7GMU0, ILVC_BACCN ;
DR   Q9K8E7, ILVC_BACHD ;  Q65GI7, ILVC_BACLD ;  A8FFW6, ILVC_BACP2 ;
DR   Q5WEN2, ILVC_BACSK ;  P37253, ILVC_BACSU ;  A1UT97, ILVC_BARBK ;
DR   Q6G2T6, ILVC_BARHE ;  Q6FZ98, ILVC_BARQU ;  A9IW67, ILVC_BART1 ;
DR   B2IHY4, ILVC_BEII9 ;  C5C2I2, ILVC_BEUC1 ;  B8DVE0, ILVC_BIFA0 ;
DR   Q7VRM0, ILVC_BLOFL ;  Q491Z2, ILVC_BLOPB ;  Q2KWH7, ILVC_BORA1 ;
DR   Q7WCP6, ILVC_BORBR ;  Q7W566, ILVC_BORPA ;  A9IGJ3, ILVC_BORPD ;
DR   Q7VZU4, ILVC_BORPE ;  C0R090, ILVC_BRAHW ;  Q89G50, ILVC_BRAJA ;
DR   A5EPB5, ILVC_BRASB ;  A4YZA6, ILVC_BRASO ;  C0Z9C7, ILVC_BREBN ;
DR   B2S6K5, ILVC_BRUA1 ;  Q2YQN2, ILVC_BRUA2 ;  Q57CC7, ILVC_BRUAB ;
DR   A9M637, ILVC_BRUC2 ;  C0RE20, ILVC_BRUMB ;  Q8YI21, ILVC_BRUME ;
DR   A5VRC9, ILVC_BRUO2 ;  B0CHG8, ILVC_BRUSI ;  Q8FZU1, ILVC_BRUSU ;
DR   B8D8F7, ILVC_BUCA5 ;  P57655, ILVC_BUCAI ;  O51888, ILVC_BUCAP ;
DR   B8D8B4, ILVC_BUCAT ;  Q89A20, ILVC_BUCBP ;  Q9RQ55, ILVC_BUCDN ;
DR   Q9RQ47, ILVC_BUCMH ;  Q9AQ96, ILVC_BUCML ;  Q9RQ51, ILVC_BUCSC ;
DR   Q9AQ97, ILVC_BUCUE ;  Q9AQ98, ILVC_BUCUL ;  Q9AQA0, ILVC_BUCUM ;
DR   Q9AQ99, ILVC_BUCUN ;  B1YTS0, ILVC_BURA4 ;  Q1BUZ9, ILVC_BURCA ;
DR   B1JVQ4, ILVC_BURCC ;  A0K937, ILVC_BURCH ;  B4E5N5, ILVC_BURCJ ;
DR   Q0BDB6, ILVC_BURCM ;  A9AJN1, ILVC_BURM1 ;  A3MI87, ILVC_BURM7 ;
DR   A2S472, ILVC_BURM9 ;  Q62IM0, ILVC_BURMA ;  A1V2K2, ILVC_BURMS ;
DR   A3NT91, ILVC_BURP0 ;  Q3JUC2, ILVC_BURP1 ;  A3N7K4, ILVC_BURP6 ;
DR   B2JDN9, ILVC_BURP8 ;  B2T2D1, ILVC_BURPP ;  Q63VP6, ILVC_BURPS ;
DR   Q39ED2, ILVC_BURS3 ;  Q2SZP8, ILVC_BURTA ;  A4JGE3, ILVC_BURVG ;
DR   Q142I6, ILVC_BURXL ;  A8MDY9, ILVC_CALMQ ;  A4XIL7, ILVC_CALS8 ;
DR   A7ZEF1, ILVC_CAMC1 ;  A7GXQ8, ILVC_CAMC5 ;  A0RQ02, ILVC_CAMFF ;
DR   A7I0D4, ILVC_CAMHC ;  A8FL53, ILVC_CAMJ8 ;  A7H4H9, ILVC_CAMJD ;
DR   Q9PHN5, ILVC_CAMJE ;  A1VYZ2, ILVC_CAMJJ ;  Q5HVD9, ILVC_CAMJR ;
DR   B9KCI3, ILVC_CAMLR ;  Q3AEQ7, ILVC_CARHZ ;  B8GXW2, ILVC_CAUCN ;
DR   Q9A6H4, ILVC_CAUCR ;  B0T4Y1, ILVC_CAUSK ;  B3PK17, ILVC_CELJU ;
DR   A0RXE1, ILVC_CENSY ;  A9WC26, ILVC_CHLAA ;  B8G7X1, ILVC_CHLAD ;
DR   Q3APC3, ILVC_CHLCH ;  B3EHP0, ILVC_CHLL2 ;  B3EKV1, ILVC_CHLPB ;
DR   A1BES5, ILVC_CHLPD ;  B9LGM7, ILVC_CHLSY ;  B3QSP0, ILVC_CHLT3 ;
DR   Q8KER7, ILVC_CHLTE ;  Q1R092, ILVC_CHRSD ;  Q7P0H9, ILVC_CHRVO ;
DR   A8ACS4, ILVC_CITK8 ;  A5CPY6, ILVC_CLAM3 ;  B0RIN6, ILVC_CLAMS ;
DR   Q97MV0, ILVC_CLOAB ;  A6LPX8, ILVC_CLOB8 ;  B2UYT8, ILVC_CLOBA ;
DR   B2TIR4, ILVC_CLOBB ;  B8I1T8, ILVC_CLOCE ;  Q18C83, ILVC_CLOD6 ;
DR   A0Q0E9, ILVC_CLONN ;  A9KQ65, ILVC_CLOPH ;  A3DIE1, ILVC_CLOTH ;
DR   Q47UP4, ILVC_COLP3 ;  C3PFX1, ILVC_CORA7 ;  Q6NHN2, ILVC_CORDI ;
DR   Q8FPX1, ILVC_COREF ;  A4QDN4, ILVC_CORGB ;  Q57179, ILVC_CORGL ;
DR   Q4JUN9, ILVC_CORJK ;  C4LJH6, ILVC_CORK4 ;  B1VG26, ILVC_CORU7 ;
DR   Q0KCU2, ILVC_CUPNH ;  Q473V5, ILVC_CUPPJ ;  B3R3V4, ILVC_CUPTR ;
DR   B1WNP1, ILVC_CYAA5 ;  B8HNI6, ILVC_CYAP4 ;  B7KF23, ILVC_CYAP7 ;
DR   B7K0S6, ILVC_CYAP8 ;  Q11VZ3, ILVC_CYTH3 ;  Q47BH8, ILVC_DECAR ;
DR   Q3Z891, ILVC_DEHE1 ;  A5FR44, ILVC_DEHSB ;  Q3ZXI2, ILVC_DEHSC ;
DR   C1CWT7, ILVC_DEIDV ;  Q1J0T2, ILVC_DEIGD ;  Q9RU74, ILVC_DEIRA ;
DR   A9BME9, ILVC_DELAS ;  C6BXE6, ILVC_DESAD ;  B8J2E2, ILVC_DESDA ;
DR   Q30ZD3, ILVC_DESDG ;  B8FU98, ILVC_DESHD ;  Q24XT5, ILVC_DESHY ;
DR   C4XSF4, ILVC_DESMR ;  A4J179, ILVC_DESRM ;  Q72CA6, ILVC_DESVH ;
DR   B8DNQ9, ILVC_DESVM ;  A1VE41, ILVC_DESVV ;  B5YEF3, ILVC_DICT6 ;
DR   B8E2W8, ILVC_DICTD ;  A8LS39, ILVC_DINSH ;  A7ZTX6, ILVC_ECO24 ;
DR   B7UMN1, ILVC_ECO27 ;  B7MGI6, ILVC_ECO45 ;  B7L8B5, ILVC_ECO55 ;
DR   P58256, ILVC_ECO57 ;  B5YY23, ILVC_ECO5E ;  B7NTG7, ILVC_ECO7I ;
DR   B7N269, ILVC_ECO81 ;  B7M5C2, ILVC_ECO8A ;  C4ZZ44, ILVC_ECOBW ;
DR   B1X9Z0, ILVC_ECODH ;  A8A6N0, ILVC_ECOHS ;  A1AHU6, ILVC_ECOK1 ;
DR   Q0TAU6, ILVC_ECOL5 ;  Q8FBR2, ILVC_ECOL6 ;  B1IWC4, ILVC_ECOLC ;
DR   P05793, ILVC_ECOLI ;  B7NF81, ILVC_ECOLU ;  B6I4B1, ILVC_ECOSE ;
DR   B1LLU9, ILVC_ECOSM ;  Q1R4G3, ILVC_ECOUT ;  C5BBA8, ILVC_EDWI9 ;
DR   A4WG34, ILVC_ENT38 ;  A7MQH1, ILVC_ENTS8 ;  Q6CZD1, ILVC_ERWCT ;
DR   B2VG69, ILVC_ERWT9 ;  Q2NAU8, ILVC_ERYLH ;  B7LU79, ILVC_ESCF3 ;
DR   A5FFY3, ILVC_FLAJ1 ;  Q0RDI8, ILVC_FRAAA ;  Q2J6V2, ILVC_FRASC ;
DR   A8L548, ILVC_FRASN ;  Q5KWJ2, ILVC_GEOKA ;  B3E5X4, ILVC_GEOLS ;
DR   Q39W76, ILVC_GEOMG ;  B9M5B1, ILVC_GEOSF ;  Q74BW9, ILVC_GEOSL ;
DR   C5D5M1, ILVC_GEOSW ;  A4IRH9, ILVC_GEOTN ;  A5G7V3, ILVC_GEOUR ;
DR   Q7NH80, ILVC_GLOVI ;  A9GZJ4, ILVC_GLUDA ;  Q5FRY8, ILVC_GLUOX ;
DR   Q0BS26, ILVC_GRABC ;  A0M380, ILVC_GRAFK ;  Q4QMN4, ILVC_HAEI8 ;
DR   A5UE34, ILVC_HAEIE ;  A5UHH1, ILVC_HAEIG ;  P44822, ILVC_HAEIN ;
DR   B8F6G2, ILVC_HAEPS ;  Q0I511, ILVC_HAES1 ;  B0UWE8, ILVC_HAES2 ;
DR   Q2S9V9, ILVC_HAHCH ;  A1WUW3, ILVC_HALHL ;  Q5V520, ILVC_HALMA ;
DR   B8CX20, ILVC_HALOH ;  Q18GT4, ILVC_HALWD ;  Q17X66, ILVC_HELAH ;
DR   Q7VGW6, ILVC_HELHP ;  B0TCQ9, ILVC_HELMI ;  C0QMX0, ILVC_HELP2 ;
DR   Q1CUH1, ILVC_HELPH ;  Q9ZMA9, ILVC_HELPJ ;  B2USG1, ILVC_HELPS ;
DR   O25097, ILVC_HELPY ;  A9AZM5, ILVC_HERA2 ;  A4G4H8, ILVC_HERAR ;
DR   B4U6I9, ILVC_HYDS0 ;  Q0C516, ILVC_HYPNA ;  A6SZZ1, ILVC_JANMA ;
DR   Q28T07, ILVC_JANSC ;  A6W7N6, ILVC_KINRD ;  B5XYZ8, ILVC_KLEP3 ;
DR   A6TGG1, ILVC_KLEP7 ;  B2GFJ7, ILVC_KOCRD ;  Q02138, ILVC_LACLA ;
DR   A2RKQ6, ILVC_LACLM ;  Q02YY8, ILVC_LACLS ;  C1DA41, ILVC_LARHH ;
DR   Q6AEP2, ILVC_LEIXX ;  B0SCQ5, ILVC_LEPBA ;  Q04P56, ILVC_LEPBJ ;
DR   Q056H8, ILVC_LEPBL ;  B0SL33, ILVC_LEPBP ;  B1XYB1, ILVC_LEPCP ;
DR   Q72M00, ILVC_LEPIC ;  Q8EYH2, ILVC_LEPIN ;  P97115, ILVC_LEUMC ;
DR   Q03UU4, ILVC_LEUMM ;  Q92A29, ILVC_LISIN ;  C1KWT0, ILVC_LISMC ;
DR   Q71Y36, ILVC_LISMF ;  B8DBU5, ILVC_LISMH ;  Q8Y5S0, ILVC_LISMO ;
DR   A0AK91, ILVC_LISW6 ;  B1HR99, ILVC_LYSSC ;  B9EBF4, ILVC_MACCJ ;
DR   Q2W1G2, ILVC_MAGSA ;  A0L626, ILVC_MAGSM ;  Q65WK8, ILVC_MANSM ;
DR   A1TZ11, ILVC_MARAV ;  A6W216, ILVC_MARMS ;  Q11I83, ILVC_MESSB ;
DR   Q8TJJ4, ILVC_METAC ;  A7I5I8, ILVC_METB6 ;  Q46FY8, ILVC_METBF ;
DR   Q12Y03, ILVC_METBU ;  B7KYZ3, ILVC_METC4 ;  Q605K9, ILVC_METCA ;
DR   A9VZF3, ILVC_METEP ;  Q1GZE9, ILVC_METFK ;  Q2FM37, ILVC_METHJ ;
DR   Q58938, ILVC_METJA ;  Q8TX44, ILVC_METKA ;  A2SR20, ILVC_METLZ ;
DR   A4FYE4, ILVC_METM5 ;  A9A7D0, ILVC_METM6 ;  A6VJW0, ILVC_METM7 ;
DR   Q8PZ26, ILVC_METMA ;  A3CXJ5, ILVC_METMJ ;  Q6LZH4, ILVC_METMP ;
DR   B8IGT3, ILVC_METNO ;  B1ZI53, ILVC_METPB ;  B8GIC5, ILVC_METPE ;
DR   A2SHM0, ILVC_METPP ;  B1LXF3, ILVC_METRJ ;  A5UMJ9, ILVC_METS3 ;
DR   B0U8N5, ILVC_METS4 ;  A4YI15, ILVC_METS5 ;  B8EKP4, ILVC_METSB ;
DR   Q2NI95, ILVC_METST ;  O27491, ILVC_METTH ;  A0B5E0, ILVC_METTP ;
DR   A6USF9, ILVC_METVS ;  B0JRP2, ILVC_MICAN ;  Q2RIS6, ILVC_MOOTA ;
DR   A0QJC6, ILVC_MYCA1 ;  Q59500, ILVC_MYCAV ;  P65150, ILVC_MYCBO ;
DR   A1KMZ6, ILVC_MYCBP ;  A4TE07, ILVC_MYCGI ;  O33114, ILVC_MYCLE ;
DR   Q73VH7, ILVC_MYCPA ;  A0QUX8, ILVC_MYCS2 ;  A3PXP9, ILVC_MYCSJ ;
DR   A1UE95, ILVC_MYCSK ;  Q1BAR7, ILVC_MYCSS ;  A5U713, ILVC_MYCTA ;
DR   P65149, ILVC_MYCTU ;  A0PPY3, ILVC_MYCUA ;  A1T6Y9, ILVC_MYCVP ;
DR   Q3IRQ2, ILVC_NATPD ;  Q5F7E5, ILVC_NEIG1 ;  A9M177, ILVC_NEIM0 ;
DR   Q9JTI3, ILVC_NEIMA ;  Q9JYI2, ILVC_NEIMB ;  A1KUZ8, ILVC_NEIMF ;
DR   Q0AGM0, ILVC_NITEC ;  Q82UZ3, ILVC_NITEU ;  Q1QJU8, ILVC_NITHX ;
DR   A9A2E4, ILVC_NITMS ;  Q2YBU1, ILVC_NITMU ;  Q3J875, ILVC_NITOC ;
DR   A6Q461, ILVC_NITSB ;  Q3SQ46, ILVC_NITWN ;  Q5YRW2, ILVC_NOCFA ;
DR   B2J2U6, ILVC_NOSP7 ;  Q8YUM5, ILVC_NOSS1 ;  Q2G623, ILVC_NOVAD ;
DR   Q8EN66, ILVC_OCEIH ;  A6WZX5, ILVC_OCHA4 ;  B6JB83, ILVC_OLICO ;
DR   A1B2W3, ILVC_PARDP ;  A7HVZ2, ILVC_PARL1 ;  Q9CLF1, ILVC_PASMU ;
DR   C6DHG3, ILVC_PECCP ;  Q3B594, ILVC_PELLD ;  B4SDK7, ILVC_PELPB ;
DR   A1AS39, ILVC_PELPD ;  Q4FPQ6, ILVC_PELUB ;  C0QTD8, ILVC_PERMH ;
DR   A9BGP6, ILVC_PETMO ;  B4RG67, ILVC_PHEZH ;  Q7MYK9, ILVC_PHOLL ;
DR   Q6LVZ5, ILVC_PHOPR ;  A1VN04, ILVC_POLNA ;  B1XUJ0, ILVC_POLNS ;
DR   Q12B50, ILVC_POLSJ ;  A4SXR3, ILVC_POLSQ ;  Q9F7L6, ILVC_PRB01 ;
DR   B4S6N3, ILVC_PROA2 ;  Q6A7Z2, ILVC_PROAC ;  A3PEE9, ILVC_PROM0 ;
DR   A2C482, ILVC_PROM1 ;  A8G6C6, ILVC_PROM2 ;  A2CB87, ILVC_PROM3 ;
DR   A9BBT2, ILVC_PROM4 ;  A2BY22, ILVC_PROM5 ;  Q319H3, ILVC_PROM9 ;
DR   Q7VAR8, ILVC_PROMA ;  B4F1U6, ILVC_PROMH ;  Q7V8M5, ILVC_PROMM ;
DR   Q7V0F0, ILVC_PROMP ;  A2BSN6, ILVC_PROMS ;  Q46JF6, ILVC_PROMT ;
DR   A4SFC5, ILVC_PROVI ;  Q48N66, ILVC_PSE14 ;  Q15MY4, ILVC_PSEA6 ;
DR   A6VCE7, ILVC_PSEA7 ;  B7V1A6, ILVC_PSEA8 ;  Q02FX9, ILVC_PSEAB ;
DR   Q9HVA2, ILVC_PSEAE ;  Q1I4R5, ILVC_PSEE4 ;  Q4K608, ILVC_PSEF5 ;
DR   C3K225, ILVC_PSEFS ;  Q3IE45, ILVC_PSEHT ;  A4XR11, ILVC_PSEMY ;
DR   A5W952, ILVC_PSEP1 ;  Q3K6T1, ILVC_PSEPF ;  B0KHU2, ILVC_PSEPG ;
DR   Q88DZ0, ILVC_PSEPK ;  B1J2D7, ILVC_PSEPW ;  Q888N4, ILVC_PSESM ;
DR   Q4ZY66, ILVC_PSEU2 ;  A4VPI6, ILVC_PSEU5 ;  Q4FUB6, ILVC_PSYA2 ;
DR   Q1QDE6, ILVC_PSYCK ;  A5WD25, ILVC_PSYWF ;  Q9UZ09, ILVC_PYRAB ;
DR   Q8ZTE1, ILVC_PYRAE ;  A4WLK6, ILVC_PYRAR ;  A3MX05, ILVC_PYRCJ ;
DR   Q8U2A3, ILVC_PYRFU ;  A1RRZ8, ILVC_PYRIL ;  Q1LPX7, ILVC_RALME ;
DR   B2U7S3, ILVC_RALPJ ;  Q8XXN8, ILVC_RALSO ;  A9WP08, ILVC_RENSM ;
DR   B3PT89, ILVC_RHIE6 ;  Q2K6M2, ILVC_RHIEC ;  Q1MED4, ILVC_RHIL3 ;
DR   Q98KM7, ILVC_RHILO ;  B5ZVQ5, ILVC_RHILW ;  Q52955, ILVC_RHIME ;
DR   C3ME70, ILVC_RHISN ;  Q7UKY0, ILVC_RHOBA ;  B6ITR6, ILVC_RHOCS ;
DR   C0ZXM2, ILVC_RHOE4 ;  Q21T70, ILVC_RHOFD ;  O32414, ILVC_RHOMO ;
DR   C1B2M1, ILVC_RHOOB ;  Q2IUS3, ILVC_RHOP2 ;  Q07PJ7, ILVC_RHOP5 ;
DR   Q6N869, ILVC_RHOPA ;  Q211Z6, ILVC_RHOPB ;  Q139A2, ILVC_RHOPS ;
DR   B3QCW2, ILVC_RHOPT ;  Q2RX71, ILVC_RHORT ;  A3PH14, ILVC_RHOS1 ;
DR   Q3J5C0, ILVC_RHOS4 ;  A4WQ93, ILVC_RHOS5 ;  B9KM37, ILVC_RHOSK ;
DR   Q0S2H3, ILVC_RHOSR ;  A7NJH8, ILVC_ROSCS ;  Q168N1, ILVC_ROSDO ;
DR   Q1ARE4, ILVC_RUBXD ;  A1AW99, ILVC_RUTMC ;  Q21HN0, ILVC_SACD2 ;
DR   A4FMQ5, ILVC_SACEN ;  B5EZ33, ILVC_SALA4 ;  A8M5F9, ILVC_SALAI ;
DR   A9MJN4, ILVC_SALAR ;  Q57HU2, ILVC_SALCH ;  B5FN70, ILVC_SALDC ;
DR   B5QVG7, ILVC_SALEP ;  B5RFS8, ILVC_SALG2 ;  B4TB09, ILVC_SALHS ;
DR   B4SZ22, ILVC_SALNS ;  Q5PJZ5, ILVC_SALPA ;  A9MXE7, ILVC_SALPB ;
DR   C0Q2V3, ILVC_SALPC ;  B5BIS2, ILVC_SALPK ;  Q2S0M9, ILVC_SALRD ;
DR   B4TNS6, ILVC_SALSV ;  Q8Z381, ILVC_SALTI ;  A4X4A5, ILVC_SALTO ;
DR   P05989, ILVC_SALTY ;  A8GL54, ILVC_SERP5 ;  A1SAS8, ILVC_SHEAM ;
DR   Q8E9D5, ILVC_SHEON ;  B2TU17, ILVC_SHIB3 ;  Q31UL0, ILVC_SHIBS ;
DR   Q329V3, ILVC_SHIDS ;  Q7UB34, ILVC_SHIFL ;  Q3YVJ0, ILVC_SHISS ;
DR   Q5LTP7, ILVC_SILPO ;  Q1GE81, ILVC_SILST ;  A6UAW6, ILVC_SINMW ;
DR   Q2NQA9, ILVC_SODGM ;  Q02CM4, ILVC_SOLUE ;  A9GW78, ILVC_SORC5 ;
DR   Q1GT37, ILVC_SPHAL ;  A5V3W3, ILVC_SPHWW ;  A7X4M9, ILVC_STAA1 ;
DR   A6U3E1, ILVC_STAA2 ;  Q2FF68, ILVC_STAA3 ;  Q2FWK4, ILVC_STAA8 ;
DR   A5IUK2, ILVC_STAA9 ;  Q2YUF3, ILVC_STAAB ;  Q5HEE5, ILVC_STAAC ;
DR   A6QIQ2, ILVC_STAAE ;  P65151, ILVC_STAAM ;  P65152, ILVC_STAAN ;
DR   Q6GF17, ILVC_STAAR ;  Q6G7Q2, ILVC_STAAS ;  A8Z4V9, ILVC_STAAT ;
DR   P65153, ILVC_STAAW ;  B9DMJ5, ILVC_STACT ;  Q5HMG0, ILVC_STAEQ ;
DR   Q8CRQ6, ILVC_STAES ;  Q4L7T9, ILVC_STAHJ ;  Q49Z11, ILVC_STAS1 ;
DR   Q59818, ILVC_STRAW ;  A8AVN4, ILVC_STRGC ;  B1VZ72, ILVC_STRGG ;
DR   Q8DW43, ILVC_STRMU ;  Q04M32, ILVC_STRP2 ;  B5E1Q6, ILVC_STRP4 ;
DR   C1C5I0, ILVC_STRP7 ;  B1I9N6, ILVC_STRPI ;  B8ZLL0, ILVC_STRPJ ;
DR   Q97SD7, ILVC_STRPN ;  B2ILY8, ILVC_STRPS ;  Q8DR03, ILVC_STRR6 ;
DR   A4W3V8, ILVC_STRS2 ;  A3CQ86, ILVC_STRSV ;  A4VXL3, ILVC_STRSY ;
DR   Q5LXV0, ILVC_STRT1 ;  Q5M2F2, ILVC_STRT2 ;  Q03IJ9, ILVC_STRTD ;
DR   Q9F0I7, ILVC_STRTR ;  C1CCK9, ILVC_STRZJ ;  C1CIU7, ILVC_STRZP ;
DR   C1CPV5, ILVC_STRZT ;  Q4J8K9, ILVC_SULAC ;  Q30T61, ILVC_SULDN ;
DR   C3N6C4, ILVC_SULIA ;  C4KHT9, ILVC_SULIK ;  C3MQK4, ILVC_SULIL ;
DR   C3MW82, ILVC_SULIM ;  C3NGW2, ILVC_SULIN ;  C3NET2, ILVC_SULIY ;
DR   B2V7F0, ILVC_SULSY ;  Q971A9, ILVC_SULTO ;  Q31MY7, ILVC_SYNE7 ;
DR   Q2JXL2, ILVC_SYNJA ;  Q2JKN5, ILVC_SYNJB ;  B1XL20, ILVC_SYNP2 ;
DR   Q5N667, ILVC_SYNP6 ;  A5GMM6, ILVC_SYNPW ;  Q7U5Q1, ILVC_SYNPX ;
DR   A5GRI8, ILVC_SYNR3 ;  Q0IC80, ILVC_SYNS3 ;  Q3AVC2, ILVC_SYNS9 ;
DR   Q3ALC5, ILVC_SYNSC ;  Q0AV19, ILVC_SYNWW ;  P29107, ILVC_SYNY3 ;
DR   C5BQZ6, ILVC_TERTT ;  Q8DGR0, ILVC_THEEB ;  Q47SB6, ILVC_THEFY ;
DR   Q9WZ20, ILVC_THEMA ;  B9KB98, ILVC_THENN ;  B1Y9N6, ILVC_THENV ;
DR   A5IJM5, ILVC_THEP1 ;  B0KAH3, ILVC_THEP3 ;  B0K0Y0, ILVC_THEPX ;
DR   B9KYS1, ILVC_THERP ;  B1L8U5, ILVC_THESQ ;  Q72JC8, ILVC_THET2 ;
DR   Q5SJ03, ILVC_THET8 ;  Q8RDK4, ILVC_THETN ;  B5YJT0, ILVC_THEYD ;
DR   Q31HZ1, ILVC_THICR ;  Q3SHE4, ILVC_THIDA ;  B8GUB6, ILVC_THISH ;
DR   C4L8N9, ILVC_TOLAT ;  Q8KTR6, ILVC_TREPR ;  Q10WP7, ILVC_TRIEI ;
DR   Q83HI9, ILVC_TROW8 ;  Q83GP6, ILVC_TROWT ;  Q0W834, ILVC_UNCMA ;
DR   C5CYN9, ILVC_VARPS ;  A5CWZ1, ILVC_VESOH ;  A5F449, ILVC_VIBC3 ;
DR   Q9KVI4, ILVC_VIBCH ;  C3LQ01, ILVC_VIBCM ;  Q5E1S3, ILVC_VIBF1 ;
DR   B5FCV4, ILVC_VIBFM ;  Q87TN4, ILVC_VIBPA ;  B7VGL9, ILVC_VIBSL ;
DR   Q8DDC8, ILVC_VIBVU ;  Q7MQH3, ILVC_VIBVY ;  Q7M851, ILVC_WOLSU ;
DR   Q8PH09, ILVC_XANAC ;  Q3BPK3, ILVC_XANC5 ;  Q4UYF7, ILVC_XANC8 ;
DR   B0RP32, ILVC_XANCB ;  Q8P5L5, ILVC_XANCP ;  Q2P757, ILVC_XANOM ;
DR   B2SNG5, ILVC_XANOP ;  Q5H4C1, ILVC_XANOR ;  A7IFE5, ILVC_XANP2 ;
DR   Q9PCF9, ILVC_XYLFA ;  Q87CM2, ILVC_XYLFT ;  A1JI57, ILVC_YERE8 ;
DR   A7FD32, ILVC_YERP3 ;  Q1CBS1, ILVC_YERPA ;  B2JZH8, ILVC_YERPB ;
DR   Q8ZAC2, ILVC_YERPE ;  A9R8G1, ILVC_YERPG ;  Q1CNM0, ILVC_YERPN ;
DR   A4TRD9, ILVC_YERPP ;  Q66G37, ILVC_YERPS ;  B1JQ26, ILVC_YERPY ;
DR   Q9X5F8, ILVC_ZYMMO ;
//
ID   1.1.1.87
DE   Homoisocitrate dehydrogenase.
AN   (-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD(+) oxidoreductase
AN   (decarboxylating).
AN   2-hydroxy-3-carboxyadipate dehydrogenase.
AN   3-carboxy-2-hydroxyadipate dehydrogenase.
AN   3-carboxy-2-hydroxyadipate:NAD(+) oxidoreductase (decarboxylating).
AN   Homoisocitric dehydrogenase.
CA   (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD(+) = 2-oxoadipate +
CA   CO(2) + NADH.
CC   -!- Forms part of the lysine biosynthesis pathway in fungi.
CC   -!- Formerly EC 1.1.1.155.
PR   PROSITE; PDOC00389;
DR   Q58991, AKSF_METJA ;  O14104, LYS12_SCHPO;  P40495, LYS12_YEAST;
//
ID   1.1.1.88
DE   Hydroxymethylglutaryl-CoA reductase.
AN   3-hydroxy-3-methylglutaryl-coenzyme A reductase.
AN   Beta-hydroxy-beta-methylglutaryl CoA-reductase.
AN   Beta-hydroxy-beta-methylglutaryl coenzyme A reductase.
AN   HMG-CoA reductase.
AN   Hydroxymethylglutaryl coenzyme A reductase.
CA   (R)-mevalonate + CoA + 2 NAD(+) = 3-hydroxy-3-methylglutaryl-CoA +
CA   2 NADH.
PR   PROSITE; PDOC00064;
DR   O51628, HMDH_BORBU ;  P13702, MVAA_PSEMV ;
//
ID   1.1.1.89
DE   Transferred entry: 1.1.1.86.
//
ID   1.1.1.90
DE   Aryl-alcohol dehydrogenase.
AN   Benzyl alcohol dehydrogenase.
AN   p-hydroxybenzyl alcohol dehydrogenase.
CA   An aromatic alcohol + NAD(+) = an aromatic aldehyde + NADH.
CC   -!- A group of enzymes with broad specificity toward primary alcohols
CC       with an aromatic or cyclohex-1-ene ring, but with low or no activity
CC       toward short-chain aliphatic alcohols.
PR   PROSITE; PDOC00058;
DR   P46364, XYLB_ACIGB ;  P39849, XYLB_PSEPU ;
//
ID   1.1.1.91
DE   Aryl-alcohol dehydrogenase (NADP(+)).
CA   An aromatic alcohol + NADP(+) = an aromatic aldehyde + NADPH.
CC   -!- Also acts on some aliphatic aldehydes, but cinnamaldehyde was the
CC       best substrate found.
DR   Q01752, AAD_PHACH  ;
//
ID   1.1.1.92
DE   Oxaloglycolate reductase (decarboxylating).
CA   D-glycerate + NAD(P)(+) + CO(2) = 2-hydroxy-3-oxosuccinate + NAD(P)H.
CC   -!- Also reduces hydroxypyruvate to D-glycerate and glyoxylate to
CC       glycolate.
//
ID   1.1.1.93
DE   Tartrate dehydrogenase.
AN   Mesotartrate dehydrogenase.
CA   (1) Tartrate + NAD(+) = oxaloglycolate + NADH.
CA   (2) Meso-tartrate + NAD(+) = oxaloglycolate + NADH.
CA   (3) (R,R)-tartrate + NAD(+) = oxaloglycolate + NADH.
CF   Manganese; Monovalent cation.
DR   Q44471, TTUC1_AGRVI;  P70787, TTUC2_AGRVI;  O34296, TTUC3_AGRVI;
DR   P70792, TTUC4_AGRVI;  O34295, TTUC5_AGRVI;  P42958, TTUC_BACSU ;
DR   Q51945, TTUC_PSEPU ;
//
ID   1.1.1.94
DE   Glycerol-3-phosphate dehydrogenase (NAD(P)(+)).
AN   Glycerol 3-phosphate dehydrogenase (NAD(P)).
AN   Glycerol 3-phosphate dehydrogenase (NADP).
AN   Glycerol phosphate dehydrogenase (nicotinamide adenine dinucleotide
AN   (phosphate)).
AN   L-glycerol-3-phosphate:NAD(P) oxidoreductase.
CA   sn-glycerol 3-phosphate + NAD(P)(+) = glycerone phosphate + NAD(P)H.
CC   -!- The enzyme from Escherichia coli shows specificity for the B side of
CC       NADPH.
PR   PROSITE; PDOC00740;
DR   Q93FD0, GPDA1_LACDA;  P61743, GPDA1_MYCPA;  Q0SE35, GPDA1_RHOSR;
DR   Q2S2I4, GPDA1_SALRD;  Q1GP43, GPDA1_SPHAL;  Q1G8H5, GPDA2_LACDA;
DR   P64189, GPDA2_MYCBO;  P61744, GPDA2_MYCPA;  P64188, GPDA2_MYCTU;
DR   Q0S2F8, GPDA2_RHOSR;  Q2S2H6, GPDA2_SALRD;  Q1GWP9, GPDA2_SPHAL;
DR   B0C2F0, GPDA_ACAM1 ;  A9NGK6, GPDA_ACHLI ;  A1TTW1, GPDA_ACIAC ;
DR   Q3V7H1, GPDA_ACIAD ;  B7GZW3, GPDA_ACIB3 ;  B7I2M0, GPDA_ACIB5 ;
DR   B2HUU0, GPDA_ACIBC ;  Q1IPR2, GPDA_ACIBL ;  B0VKB4, GPDA_ACIBS ;
DR   A3M6Y6, GPDA_ACIBT ;  B0V862, GPDA_ACIBY ;  C1F6U2, GPDA_ACIC5 ;
DR   A5FYL0, GPDA_ACICJ ;  B9MEY8, GPDA_ACIET ;  B7J4Y4, GPDA_ACIF2 ;
DR   B5EKH1, GPDA_ACIF5 ;  A1WBI9, GPDA_ACISJ ;  A3N2F8, GPDA_ACTP2 ;
DR   B3GYJ1, GPDA_ACTP7 ;  B0BRA3, GPDA_ACTPJ ;  A0KF08, GPDA_AERHH ;
DR   A4ST20, GPDA_AERS4 ;  Q8UC48, GPDA_AGRT5 ;  Q0VPG2, GPDA_ALCBS ;
DR   Q0A5H5, GPDA_ALHEH ;  B8JAX1, GPDA_ANAD2 ;  Q2IMY8, GPDA_ANADE ;
DR   Q5PA02, GPDA_ANAMM ;  Q2GLD0, GPDA_ANAPZ ;  B4UB18, GPDA_ANASK ;
DR   Q3MDZ9, GPDA_ANAVT ;  O67555, GPDA_AQUAE ;  O29390, GPDA_ARCFU ;
DR   Q5P7M9, GPDA_AROAE ;  Q2NIZ6, GPDA_AYWBP ;  A8IJ80, GPDA_AZOC5 ;
DR   C1DLY5, GPDA_AZOVD ;  A7Z635, GPDA_BACA2 ;  C3P592, GPDA_BACAA ;
DR   C3L9F3, GPDA_BACAC ;  A0RBW0, GPDA_BACAH ;  Q81SW8, GPDA_BACAN ;
DR   B7JGZ0, GPDA_BACC0 ;  P61737, GPDA_BACC1 ;  B7IP83, GPDA_BACC2 ;
DR   C1EN02, GPDA_BACC3 ;  B7HHQ8, GPDA_BACC4 ;  B7HL15, GPDA_BACC7 ;
DR   A7GN42, GPDA_BACCN ;  B9IVM7, GPDA_BACCQ ;  Q81FR4, GPDA_BACCR ;
DR   Q63DM7, GPDA_BACCZ ;  Q9KCD2, GPDA_BACHD ;  Q6HL50, GPDA_BACHK ;
DR   Q65I16, GPDA_BACLD ;  A8FEL7, GPDA_BACP2 ;  Q5WGU2, GPDA_BACSK ;
DR   P46919, GPDA_BACSU ;  A9VMB4, GPDA_BACWK ;  A1UTZ3, GPDA_BARBK ;
DR   Q6G518, GPDA_BARHE ;  Q6G0U8, GPDA_BARQU ;  A9IM16, GPDA_BART1 ;
DR   Q1LTT0, GPDA_BAUCH ;  B2ID14, GPDA_BEII9 ;  B3DTU0, GPDA_BIFLD ;
DR   Q8G7C3, GPDA_BIFLO ;  B7GU03, GPDA_BIFLS ;  Q7VRK7, GPDA_BLOFL ;
DR   Q491Y0, GPDA_BLOPB ;  Q2L0B2, GPDA_BORA1 ;  Q7WQN6, GPDA_BORBR ;
DR   Q7W1R0, GPDA_BORPA ;  Q7VS47, GPDA_BORPE ;  C0QYQ8, GPDA_BRAHW ;
DR   Q89WW0, GPDA_BRAJA ;  A5E8T9, GPDA_BRASB ;  A4YK34, GPDA_BRASO ;
DR   B2S844, GPDA_BRUA1 ;  Q2YLR3, GPDA_BRUA2 ;  Q57B06, GPDA_BRUAB ;
DR   A9M8M4, GPDA_BRUC2 ;  C0RFD3, GPDA_BRUMB ;  P64186, GPDA_BRUME ;
DR   A5VSL7, GPDA_BRUO2 ;  B0CIE1, GPDA_BRUSI ;  P64187, GPDA_BRUSU ;
DR   B1YNA2, GPDA_BURA4 ;  Q1BTB5, GPDA_BURCA ;  B1JZ57, GPDA_BURCC ;
DR   A0KAS6, GPDA_BURCH ;  B4EA68, GPDA_BURCJ ;  Q0BBK9, GPDA_BURCM ;
DR   A9AEK1, GPDA_BURM1 ;  A3MQ27, GPDA_BURM7 ;  A2S629, GPDA_BURM9 ;
DR   Q62F47, GPDA_BURMA ;  A1UZX5, GPDA_BURMS ;  A3NR13, GPDA_BURP0 ;
DR   Q3JWH3, GPDA_BURP1 ;  B2JC99, GPDA_BURP8 ;  B2SX19, GPDA_BURPP ;
DR   Q63XU3, GPDA_BURPS ;  Q39CP0, GPDA_BURS3 ;  Q2T1H1, GPDA_BURTA ;
DR   A4JI41, GPDA_BURVG ;  Q146B6, GPDA_BURXL ;  A8FMQ2, GPDA_CAMJ8 ;
DR   A7H2I1, GPDA_CAMJD ;  Q9PN99, GPDA_CAMJE ;  A1W0I0, GPDA_CAMJJ ;
DR   Q5HTR8, GPDA_CAMJR ;  B9KD88, GPDA_CAMLR ;  Q3AAU8, GPDA_CARHZ ;
DR   P58141, GPDA_CAUCR ;  B0T285, GPDA_CAUSK ;  B3PHG2, GPDA_CELJU ;
DR   Q5L4X5, GPDA_CHLAB ;  Q3AP01, GPDA_CHLCH ;  Q821M8, GPDA_CHLCV ;
DR   Q256B4, GPDA_CHLFF ;  B3EI28, GPDA_CHLL2 ;  Q9PLL2, GPDA_CHLMU ;
DR   B3EPU7, GPDA_CHLPB ;  A1BJJ1, GPDA_CHLPD ;  Q9Z751, GPDA_CHLPN ;
DR   B0B8U0, GPDA_CHLT2 ;  Q3KKY0, GPDA_CHLTA ;  B0BAG9, GPDA_CHLTB ;
DR   Q8KG76, GPDA_CHLTE ;  O84719, GPDA_CHLTR ;  Q1QUM1, GPDA_CHRSD ;
DR   Q7NYZ3, GPDA_CHRVO ;  A8ARJ5, GPDA_CITK8 ;  Q97ID6, GPDA_CLOAB ;
DR   A6LSI7, GPDA_CLOB8 ;  B2V3Z2, GPDA_CLOBA ;  B2THR0, GPDA_CLOBB ;
DR   Q0TPK0, GPDA_CLOP1 ;  Q8XJK2, GPDA_CLOPE ;  Q0SS67, GPDA_CLOPS ;
DR   Q895X7, GPDA_CLOTE ;  Q47VY6, GPDA_COLP3 ;  C3PFZ8, GPDA_CORA7 ;
DR   P61738, GPDA_CORDI ;  Q8FPR0, GPDA_COREF ;  A4QDT3, GPDA_CORGB ;
DR   Q8NQV3, GPDA_CORGL ;  Q4JUX5, GPDA_CORJK ;  C4LJE8, GPDA_CORK4 ;
DR   B1VG48, GPDA_CORU7 ;  B6J4L3, GPDA_COXB1 ;  B6IYY5, GPDA_COXB2 ;
DR   A9KF85, GPDA_COXBN ;  A9N956, GPDA_COXBR ;  Q83BJ0, GPDA_COXBU ;
DR   Q0KET4, GPDA_CUPNH ;  Q476J3, GPDA_CUPPJ ;  B2AGQ1, GPDA_CUPTR ;
DR   Q47IF9, GPDA_DECAR ;  Q3Z6P3, GPDA_DEHE1 ;  A5FPU2, GPDA_DEHSB ;
DR   Q3ZYV3, GPDA_DEHSC ;  Q1IWP7, GPDA_DEIGD ;  Q9RR76, GPDA_DEIRA ;
DR   A9BUZ7, GPDA_DELAS ;  C6BYZ0, GPDA_DESAD ;  B8J2B6, GPDA_DESDA ;
DR   Q30WH4, GPDA_DESDG ;  Q24VA4, GPDA_DESHY ;  C4XLT6, GPDA_DESMR ;
DR   Q6AQJ3, GPDA_DESPS ;  A4J3P3, GPDA_DESRM ;  P61739, GPDA_DESVH ;
DR   A1V9Y4, GPDA_DESVV ;  B5YEC5, GPDA_DICT6 ;  A7ZTG2, GPDA_ECO24 ;
DR   B7ULG4, GPDA_ECO27 ;  B7MFH2, GPDA_ECO45 ;  B7L734, GPDA_ECO55 ;
DR   P0A6S9, GPDA_ECO57 ;  B5YWB0, GPDA_ECO5E ;  B7NPB7, GPDA_ECO7I ;
DR   B7N254, GPDA_ECO81 ;  B7M495, GPDA_ECO8A ;  C4ZXK0, GPDA_ECOBW ;
DR   B1X942, GPDA_ECODH ;  A8A673, GPDA_ECOHS ;  A1AHE5, GPDA_ECOK1 ;
DR   Q0TBJ8, GPDA_ECOL5 ;  P0A6S8, GPDA_ECOL6 ;  B1IZI2, GPDA_ECOLC ;
DR   P0A6S7, GPDA_ECOLI ;  B7NER5, GPDA_ECOLU ;  B6I3I7, GPDA_ECOSE ;
DR   B1LK47, GPDA_ECOSM ;  Q1R4Y7, GPDA_ECOUT ;  C5BC33, GPDA_EDWI9 ;
DR   Q3YRF6, GPDA_EHRCJ ;  Q2GHC3, GPDA_EHRCR ;  Q5FG15, GPDA_EHRRG ;
DR   Q93FR9, GPDA_EHRRU ;  Q5HAM0, GPDA_EHRRW ;  A4W537, GPDA_ENT38 ;
DR   Q834C1, GPDA_ENTFA ;  A7MQ75, GPDA_ENTS8 ;  Q6DAT0, GPDA_ERWCT ;
DR   B2VL53, GPDA_ERWT9 ;  Q2N8R6, GPDA_ERYLH ;  B7LTL5, GPDA_ESCF3 ;
DR   C4ZD61, GPDA_EUBR3 ;  C4L6M4, GPDA_EXISA ;  B0U030, GPDA_FRAP2 ;
DR   Q2J6X6, GPDA_FRASC ;  A8L577, GPDA_FRASN ;  Q14HX3, GPDA_FRAT1 ;
DR   A7NA69, GPDA_FRATF ;  Q2A554, GPDA_FRATH ;  B2SF49, GPDA_FRATM ;
DR   A0Q4Y5, GPDA_FRATN ;  Q0BNG9, GPDA_FRATO ;  Q5NGH1, GPDA_FRATT ;
DR   A4IYT2, GPDA_FRATW ;  Q8RF18, GPDA_FUSNN ;  B5E7Q3, GPDA_GEOBB ;
DR   Q5KXT1, GPDA_GEOKA ;  B3E9A1, GPDA_GEOLS ;  Q39ZR6, GPDA_GEOMG ;
DR   P61740, GPDA_GEOSL ;  C6E7R1, GPDA_GEOSM ;  A4IQA1, GPDA_GEOTN ;
DR   Q7NF59, GPDA_GLOVI ;  Q5FPS8, GPDA_GLUOX ;  Q7VNA0, GPDA_HAEDU ;
DR   Q4QMJ1, GPDA_HAEI8 ;  A5UAS0, GPDA_HAEIE ;  P43798, GPDA_HAEIN ;
DR   B8F6W7, GPDA_HAEPS ;  Q2SIH7, GPDA_HAHCH ;  A1WWC7, GPDA_HALHL ;
DR   B8CWZ1, GPDA_HALOH ;  Q17X25, GPDA_HELAH ;  Q7VI15, GPDA_HELHP ;
DR   B6JMI1, GPDA_HELP2 ;  Q1CSR0, GPDA_HELPH ;  Q9ZKP0, GPDA_HELPJ ;
DR   B2UUA7, GPDA_HELPS ;  O25614, GPDA_HELPY ;  A4G993, GPDA_HERAR ;
DR   Q0C3I7, GPDA_HYPNA ;  Q5QZB8, GPDA_IDILO ;  A6T310, GPDA_JANMA ;
DR   Q28JW6, GPDA_JANSC ;  B5XTJ2, GPDA_KLEP3 ;  A6TFK3, GPDA_KLEP7 ;
DR   Q5FL70, GPDA_LACAC ;  Q03SN4, GPDA_LACBA ;  Q03AM6, GPDA_LACC3 ;
DR   B3WCP6, GPDA_LACCB ;  B2GAJ3, GPDA_LACF3 ;  A8YUC9, GPDA_LACH4 ;
DR   P61741, GPDA_LACJO ;  Q9CFX6, GPDA_LACLA ;  A2RK98, GPDA_LACLM ;
DR   Q02YK1, GPDA_LACLS ;  Q88YK1, GPDA_LACPL ;  A5VIG6, GPDA_LACRD ;
DR   B2G5Z4, GPDA_LACRJ ;  Q1WV00, GPDA_LACS1 ;  Q38YA9, GPDA_LACSS ;
DR   Q1MQ45, GPDA_LAWIP ;  Q5X2Y0, GPDA_LEGPA ;  A5IEA7, GPDA_LEGPC ;
DR   Q5ZT56, GPDA_LEGPH ;  Q5WUE0, GPDA_LEGPL ;  Q6AFK3, GPDA_LEIXX ;
DR   B0SAV3, GPDA_LEPBA ;  Q04VF9, GPDA_LEPBJ ;  Q04Y15, GPDA_LEPBL ;
DR   B0SKD9, GPDA_LEPBP ;  B1Y6P0, GPDA_LEPCP ;  P61742, GPDA_LEPIC ;
DR   Q8EZB6, GPDA_LEPIN ;  B1MZX5, GPDA_LEUCK ;  Q03YL0, GPDA_LEUMM ;
DR   Q92A72, GPDA_LISIN ;  C1KWN6, GPDA_LISMC ;  Q71Y79, GPDA_LISMF ;
DR   B8DBZ0, GPDA_LISMH ;  Q8Y5W9, GPDA_LISMO ;  A0AK48, GPDA_LISW6 ;
DR   B1HT97, GPDA_LYSSC ;  B9E6L4, GPDA_MACCJ ;  Q2W015, GPDA_MAGSA ;
DR   Q65QE0, GPDA_MANSM ;  Q0ATQ3, GPDA_MARMM ;  Q6F1R6, GPDA_MESFL ;
DR   Q11DE9, GPDA_MESSB ;  Q604K1, GPDA_METCA ;  Q1GZ87, GPDA_METFK ;
DR   A2SDP0, GPDA_METPP ;  B1M7L6, GPDA_METRJ ;  O26468, GPDA_METTH ;
DR   Q2RIV6, GPDA_MOOTA ;  A0QLB8, GPDA_MYCA1 ;  P59961, GPDA_MYCBO ;
DR   Q9CBR9, GPDA_MYCLE ;  Q6KHG2, GPDA_MYCMO ;  Q8EWH5, GPDA_MYCPE ;
DR   P95113, GPDA_MYCTU ;  Q1DCL2, GPDA_MYXXD ;  Q5F5A8, GPDA_NEIG1 ;
DR   B4RQK9, GPDA_NEIG2 ;  A9M084, GPDA_NEIM0 ;  Q9JWH0, GPDA_NEIMA ;
DR   Q9JXG6, GPDA_NEIMB ;  A1KWD9, GPDA_NEIMF ;  Q2GEH4, GPDA_NEOSM ;
DR   Q0AIA0, GPDA_NITEC ;  Q82SU6, GPDA_NITEU ;  Q1QQP7, GPDA_NITHX ;
DR   Q2Y9Z2, GPDA_NITMU ;  Q3JF19, GPDA_NITOC ;  A6Q3B2, GPDA_NITSB ;
DR   Q3SVF5, GPDA_NITWN ;  Q5YRY6, GPDA_NOCFA ;  Q8YWC2, GPDA_NOSS1 ;
DR   Q2G4K3, GPDA_NOVAD ;  Q8EQA9, GPDA_OCEIH ;  B6JAF0, GPDA_OLICO ;
DR   P61745, GPDA_ONYPE ;  A5CE97, GPDA_ORITB ;  B3CSW2, GPDA_ORITI ;
DR   A1B3J7, GPDA_PARDP ;  A7HST0, GPDA_PARL1 ;  Q6MF42, GPDA_PARUW ;
DR   Q9CL17, GPDA_PASMU ;  C6DIA2, GPDA_PECCP ;  Q03GY3, GPDA_PEDPA ;
DR   Q3A8M2, GPDA_PELCD ;  Q3B182, GPDA_PELLD ;  B4SGX6, GPDA_PELPB ;
DR   A5D1U4, GPDA_PELTS ;  A9BHX5, GPDA_PETMO ;  Q7MY54, GPDA_PHOLL ;
DR   Q6LVK9, GPDA_PHOPR ;  B1VAP5, GPDA_PHYAS ;  B3R0E3, GPDA_PHYMT ;
DR   A1VKS0, GPDA_POLNA ;  B1XS88, GPDA_POLNS ;  Q12F46, GPDA_POLSJ ;
DR   A4T092, GPDA_POLSQ ;  B4S674, GPDA_PROA2 ;  Q48K59, GPDA_PSE14 ;
DR   A6V7H8, GPDA_PSEA7 ;  B7UVA7, GPDA_PSEA8 ;  Q02K99, GPDA_PSEAB ;
DR   Q9I3A8, GPDA_PSEAE ;  Q1I7N0, GPDA_PSEE4 ;  Q4KFW6, GPDA_PSEF5 ;
DR   C3K747, GPDA_PSEFS ;  Q3IIE0, GPDA_PSEHT ;  Q59680, GPDA_PSELE ;
DR   A4XV57, GPDA_PSEMY ;  A5W144, GPDA_PSEP1 ;  Q3K8F9, GPDA_PSEPF ;
DR   B0KNV2, GPDA_PSEPG ;  Q88FC9, GPDA_PSEPK ;  B1JAT7, GPDA_PSEPW ;
DR   Q883Y4, GPDA_PSESM ;  Q4ZUV7, GPDA_PSEU2 ;  Q4FS72, GPDA_PSYA2 ;
DR   Q1QBS6, GPDA_PSYCK ;  A1SZH9, GPDA_PSYIN ;  Q1LRT5, GPDA_RALME ;
DR   Q8Y2H9, GPDA_RALSO ;  B3PQA3, GPDA_RHIE6 ;  Q2K3D8, GPDA_RHIEC ;
DR   Q1MAQ9, GPDA_RHIL3 ;  P58142, GPDA_RHILO ;  B5ZTC4, GPDA_RHILW ;
DR   Q9R9L6, GPDA_RHIME ;  C3MAF3, GPDA_RHISN ;  Q21YV6, GPDA_RHOFD ;
DR   Q2J3D3, GPDA_RHOP2 ;  Q07VK7, GPDA_RHOP5 ;  P61746, GPDA_RHOPA ;
DR   Q21DB2, GPDA_RHOPB ;  Q13DY0, GPDA_RHOPS ;  B3Q866, GPDA_RHOPT ;
DR   Q2RND0, GPDA_RHORT ;  Q3J6D1, GPDA_RHOS4 ;  C3PNH2, GPDA_RICAE ;
DR   A8GNH3, GPDA_RICAH ;  A8GUW7, GPDA_RICB8 ;  Q1RH58, GPDA_RICBR ;
DR   Q92I05, GPDA_RICCN ;  Q4ULP5, GPDA_RICFE ;  A8F1L7, GPDA_RICM5 ;
DR   Q9ZDA0, GPDA_RICPR ;  B0BXL6, GPDA_RICRO ;  A8GS50, GPDA_RICRS ;
DR   Q68WT6, GPDA_RICTY ;  Q16CW4, GPDA_ROSDO ;  A1AXJ0, GPDA_RUTMC ;
DR   Q21IX1, GPDA_SACD2 ;  B5EXB5, GPDA_SALA4 ;  A9MKR6, GPDA_SALAR ;
DR   Q57ID3, GPDA_SALCH ;  B5FLH8, GPDA_SALDC ;  B5R5D3, GPDA_SALEP ;
DR   B5RGH8, GPDA_SALG2 ;  B4T993, GPDA_SALHS ;  B4SXB1, GPDA_SALNS ;
DR   Q5PBZ6, GPDA_SALPA ;  A9MVK2, GPDA_SALPB ;  C0Q1U2, GPDA_SALPC ;
DR   B5BHY3, GPDA_SALPK ;  B4TZV1, GPDA_SALSV ;  P0A1P3, GPDA_SALTI ;
DR   P0A1P2, GPDA_SALTY ;  Q8KRM1, GPDA_SERMA ;  A8GLB8, GPDA_SERP5 ;
DR   A1S1L9, GPDA_SHEAM ;  B8E3F7, GPDA_SHEB2 ;  A3DAM7, GPDA_SHEB5 ;
DR   A6WHD0, GPDA_SHEB8 ;  A9KUC1, GPDA_SHEB9 ;  Q12HV8, GPDA_SHEDO ;
DR   Q07VX1, GPDA_SHEFN ;  B0TLE9, GPDA_SHEHH ;  A3QJM1, GPDA_SHELP ;
DR   Q8EKN9, GPDA_SHEON ;  A8HAD7, GPDA_SHEPA ;  A4Y1E6, GPDA_SHEPC ;
DR   B8CGT3, GPDA_SHEPW ;  A0KR80, GPDA_SHESA ;  A8G1U6, GPDA_SHESH ;
DR   Q0HP88, GPDA_SHESM ;  Q0I0Q3, GPDA_SHESR ;  A1RQ92, GPDA_SHESW ;
DR   B1KQ10, GPDA_SHEWM ;  B2U5C7, GPDA_SHIB3 ;  Q31V13, GPDA_SHIBS ;
DR   Q329P6, GPDA_SHIDS ;  Q0SYD4, GPDA_SHIF8 ;  P0A6T0, GPDA_SHIFL ;
DR   Q3YVX3, GPDA_SHISS ;  Q5LLR6, GPDA_SILPO ;  Q1GCQ4, GPDA_SILST ;
DR   Q2NQW6, GPDA_SODGM ;  A7X2I0, GPDA_STAA1 ;  A6U1U2, GPDA_STAA2 ;
DR   Q2FGW8, GPDA_STAA3 ;  Q2FYG1, GPDA_STAA8 ;  A5IT02, GPDA_STAA9 ;
DR   Q2YY82, GPDA_STAAB ;  Q5HFU9, GPDA_STAAC ;  A6QH23, GPDA_STAAE ;
DR   P64190, GPDA_STAAM ;  P64191, GPDA_STAAN ;  Q6GGT7, GPDA_STAAR ;
DR   Q6G989, GPDA_STAAS ;  A8Z453, GPDA_STAAT ;  Q8NWM9, GPDA_STAAW ;
DR   B9DNV8, GPDA_STACT ;  Q5HP71, GPDA_STAEQ ;  Q8CP63, GPDA_STAES ;
DR   Q4L6H9, GPDA_STAHJ ;  Q49XS8, GPDA_STAS1 ;  Q3K2X7, GPDA_STRA1 ;
DR   Q8E6W6, GPDA_STRA3 ;  Q8E1E8, GPDA_STRA5 ;  Q82JS4, GPDA_STRAW ;
DR   Q9ZBS0, GPDA_STRCO ;  C0M6I2, GPDA_STRE4 ;  B4U0Q8, GPDA_STREM ;
DR   A8AUM5, GPDA_STRGC ;  B1VYZ6, GPDA_STRGG ;  B4SSF9, GPDA_STRM5 ;
DR   B2FHD8, GPDA_STRMK ;  Q93D83, GPDA_STRMU ;  P68887, GPDA_STRP1 ;
DR   Q04I82, GPDA_STRP2 ;  P0DB22, GPDA_STRP3 ;  B5E399, GPDA_STRP4 ;
DR   Q5XE03, GPDA_STRP6 ;  C1CAR8, GPDA_STRP7 ;  P68889, GPDA_STRP8 ;
DR   Q1JDQ0, GPDA_STRPB ;  Q1JNL6, GPDA_STRPC ;  Q1JIR5, GPDA_STRPD ;
DR   Q1J8M2, GPDA_STRPF ;  A2RCE5, GPDA_STRPG ;  B1I9F8, GPDA_STRPI ;
DR   B8ZPL4, GPDA_STRPJ ;  Q48VF4, GPDA_STRPM ;  Q97NF1, GPDA_STRPN ;
DR   P0DB23, GPDA_STRPQ ;  B2IN10, GPDA_STRPS ;  B5XJM4, GPDA_STRPZ ;
DR   Q8DN59, GPDA_STRR6 ;  A4W4A9, GPDA_STRS2 ;  C0MFI2, GPDA_STRS7 ;
DR   A3CQT0, GPDA_STRSV ;  A4VY17, GPDA_STRSY ;  Q5LXY7, GPDA_STRT1 ;
DR   Q5M2J1, GPDA_STRT2 ;  Q03IN5, GPDA_STRTD ;  B9DVX9, GPDA_STRU0 ;
DR   C1CH20, GPDA_STRZJ ;  C1CN37, GPDA_STRZP ;  C1CTZ5, GPDA_STRZT ;
DR   Q30QX3, GPDA_SULDN ;  B2V656, GPDA_SULSY ;  Q67NS7, GPDA_SYMTH ;
DR   Q935Z2, GPDA_SYNE7 ;  A0LLR7, GPDA_SYNFM ;  Q2JX02, GPDA_SYNJA ;
DR   Q2JPE4, GPDA_SYNJB ;  A5GTA8, GPDA_SYNR3 ;  Q0AXC3, GPDA_SYNWW ;
DR   P73033, GPDA_SYNY3 ;  C5BL79, GPDA_TERTT ;  Q8DH49, GPDA_THEEB ;
DR   Q47S98, GPDA_THEFY ;  B0K8N5, GPDA_THEP3 ;  B0K3E2, GPDA_THEPX ;
DR   P61747, GPDA_THET2 ;  Q5SHJ0, GPDA_THET8 ;  Q8R9J3, GPDA_THETN ;
DR   Q31E81, GPDA_THICR ;  Q3SG93, GPDA_THIDA ;  B8GR94, GPDA_THISH ;
DR   C4LA09, GPDA_TOLAT ;  P61748, GPDA_TREDE ;  O83973, GPDA_TREPA ;
DR   B2S4P6, GPDA_TREPS ;  Q83I37, GPDA_TROW8 ;  Q83G27, GPDA_TROWT ;
DR   C5CWV5, GPDA_VARPS ;  A1WDX8, GPDA_VEREI ;  A5CVT6, GPDA_VESOH ;
DR   A5F502, GPDA_VIBC3 ;  Q9KNT0, GPDA_VIBCH ;  C3LRW2, GPDA_VIBCM ;
DR   Q5E2A3, GPDA_VIBF1 ;  A7MX60, GPDA_VIBHB ;  Q87KZ2, GPDA_VIBPA ;
DR   Q8DCW4, GPDA_VIBVU ;  Q7MGY7, GPDA_VIBVY ;  Q8D216, GPDA_WIGBR ;
DR   P61749, GPDA_WOLPM ;  B3CLC5, GPDA_WOLPP ;  Q7M7Y3, GPDA_WOLSU ;
DR   Q5GS39, GPDA_WOLTR ;  C0R3K2, GPDA_WOLWR ;  Q8PQU9, GPDA_XANAC ;
DR   Q3BZ75, GPDA_XANC5 ;  Q4V072, GPDA_XANC8 ;  B0RLW9, GPDA_XANCB ;
DR   Q8PDY0, GPDA_XANCP ;  Q2NYA5, GPDA_XANOM ;  Q5GV21, GPDA_XANOR ;
DR   B2I5B4, GPDA_XYLF2 ;  Q9PCH7, GPDA_XYLFA ;  B0U2T8, GPDA_XYLFM ;
DR   Q87CK3, GPDA_XYLFT ;  A1JHY5, GPDA_YERE8 ;  A7FCV2, GPDA_YERP3 ;
DR   Q1C286, GPDA_YERPA ;  B2JYQ1, GPDA_YERPB ;  Q8ZJM6, GPDA_YERPE ;
DR   A9R691, GPDA_YERPG ;  Q1CD21, GPDA_YERPN ;  A4TSB8, GPDA_YERPP ;
DR   Q66GB8, GPDA_YERPS ;  B1JQV5, GPDA_YERPY ;  Q5NL81, GPDA_ZYMMO ;
//
ID   1.1.1.95
DE   Phosphoglycerate dehydrogenase.
AN   3-phosphoglycerate dehydrogenase.
AN   3-phosphoglyceric acid dehydrogenase.
AN   3PHP reductase.
AN   Alpha-KG reductase.
AN   Alpha-phosphoglycerate dehydrogenase.
AN   D-3-phosphoglycerate dehydrogenase.
AN   Glycerate 3-phosphate dehydrogenase.
AN   Glycerate-1,3-phosphate dehydrogenase.
AN   PGDH.
AN   Phosphoglycerate oxidoreductase.
AN   Phosphoglyceric acid dehydrogenase.
CA   (1) 3-phospho-D-glycerate + NAD(+) = 3-phosphonooxypyruvate + NADH.
CA   (2) 2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + NADH.
CC   -!- Catalyzes the first committed step in the phosphoserine pathway of
CC       serine biosynthesis in Escherichia coli.
CC   -!- Reaction (1) occurs predominantly in the reverse direction and is
CC       inhibited by serine and glycine.
CC   -!- The enzyme is unusual in that it also acts as a D- and L-2-
CC       hydroxyglutarate dehydrogenase (with the D-form being the better
CC       substrate) and as a 2-oxoglutarate reductase.
PR   PROSITE; PDOC00063;
DR   P40510, SER33_YEAST;  O04130, SERA_ARATH ;  O29445, SERA_ARCFU ;
DR   P35136, SERA_BACSU ;  Q5EAD2, SERA_BOVIN ;  Q54UH8, SERA_DICDI ;
DR   P0A9T2, SERA_ECO57 ;  P0A9T1, SERA_ECOL6 ;  P0A9T0, SERA_ECOLI ;
DR   P43885, SERA_HAEIN ;  O43175, SERA_HUMAN ;  Q60HD7, SERA_MACFA ;
DR   Q58424, SERA_METJA ;  O27051, SERA_METTH ;  Q61753, SERA_MOUSE ;
DR   P0A545, SERA_MYCBO ;  O33116, SERA_MYCLE ;  P0A544, SERA_MYCTU ;
DR   A5A6P1, SERA_PANTR ;  A5GFY8, SERA_PIG   ;  Q5R7M2, SERA_PONAB ;
DR   O08651, SERA_RAT   ;  P87228, SERA_SCHPO ;  P0A9T3, SERA_SHIFL ;
DR   P73821, SERA_SYNY3 ;  P40054, SERA_YEAST ;
//
ID   1.1.1.96
DE   Diiodophenylpyruvate reductase.
CA   3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD(+) = 3-(3,5-diiodo-4-
CA   hydroxyphenyl)pyruvate + NADH.
CC   -!- Substrates contain an aromatic ring with a pyruvate side chain.
CC   -!- The most active substrates are halogenated derivatives.
CC   -!- Compounds with hydroxy or amino groups in the 3 or 5 position are
CC       inactive.
//
ID   1.1.1.97
DE   3-hydroxybenzyl-alcohol dehydrogenase.
AN   m-hydroxybenzyl alcohol dehydrogenase.
CA   3-hydroxybenzyl alcohol + NADP(+) = 3-hydroxybenzaldehyde + NADPH.
//
ID   1.1.1.98
DE   (R)-2-hydroxy-fatty-acid dehydrogenase.
AN   D-2-hydroxy fatty acid dehydrogenase.
CA   (R)-2-hydroxystearate + NAD(+) = 2-oxostearate + NADH.
//
ID   1.1.1.99
DE   (S)-2-hydroxy-fatty-acid dehydrogenase.
AN   L-2-hydroxy fatty acid dehydrogenase.
CA   (S)-2-hydroxystearate + NAD(+) = 2-oxostearate + NADH.
//
ID   1.1.1.100
DE   3-oxoacyl-[acyl-carrier-protein] reductase.
CA   (3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP(+) = 3-oxoacyl-[acyl-
CA   carrier-protein] + NADPH.
CC   -!- Exhibits a marked preference for [acyl-carrier-protein] derivatives
CC       over CoA derivatives as substrates.
PR   PROSITE; PDOC00060;
DR   Q93X62, FABG1_BRANA;  P73574, FABG1_SYNY3;  Q93X67, FABG2_BRANA;
DR   P73826, FABG2_SYNY3;  Q949M3, FABG3_BRANA;  Q949M2, FABG4_BRANA;
DR   Q93X68, FABG5_BRANA;  P27582, FABG6_BRANA;  P70720, FABG_AGGAC ;
DR   O67610, FABG_AQUAE ;  P33207, FABG_ARATH ;  P51831, FABG_BACSU ;
DR   P57432, FABG_BUCAI ;  Q8K9J5, FABG_BUCAP ;  Q89AG9, FABG_BUCBP ;
DR   Q9PKF7, FABG_CHLMU ;  Q9Z8P2, FABG_CHLPN ;  P38004, FABG_CHLTR ;
DR   P28643, FABG_CUPLA ;  P0AEK2, FABG_ECOLI ;  P43713, FABG_HAEIN ;
DR   O07399, FABG_MYCAV ;  P0A5Y5, FABG_MYCBO ;  P71534, FABG_MYCS2 ;
DR   P0A5Y4, FABG_MYCTU ;  P27583, FABG_PERAE ;  O54438, FABG_PSEAE ;
DR   Q1RKB7, FABG_RICBR ;  Q92GE0, FABG_RICCN ;  Q4UK62, FABG_RICFE ;
DR   P50941, FABG_RICPR ;  Q68VY7, FABG_RICTY ;  P0A2D0, FABG_SALTI ;
DR   P0A2C9, FABG_SALTY ;  O42866, FABG_SCHPO ;  P0AEK3, FABG_SHIFL ;
DR   Q5HGK2, FABG_STAAC ;  P0A0H9, FABG_STAAM ;  P99093, FABG_STAAN ;
DR   Q6GHK4, FABG_STAAR ;  Q6G9Y2, FABG_STAAS ;  P0A0I0, FABG_STAAW ;
DR   Q5HPW0, FABG_STAEQ ;  Q8CPI3, FABG_STAES ;  Q9X248, FABG_THEMA ;
DR   Q9KQH7, FABG_VIBCH ;  P55336, FABG_VIBHA ;  P35731, FABG_YEAST ;
DR   P43098, FAS2_CANAL ;  P15368, FAS2_PENPA ;  Q10289, FAS2_SCHPO ;
DR   P19097, FAS2_YEAST ;  Q71SP7, FAS_BOVIN  ;  P12276, FAS_CHICK  ;
DR   P49327, FAS_HUMAN  ;  P19096, FAS_MOUSE  ;  P12785, FAS_RAT    ;
DR   Q9RPT1, RHLG_PSEAE ;
//
ID   1.1.1.101
DE   Acylglycerone-phosphate reductase.
AN   Palmitoyldihydroxyacetone-phosphate reductase.
CA   1-palmitoylglycerol 3-phosphate + NADP(+) = palmitoylglycerone phosphate
CA   + NADPH.
CC   -!- Also acts on alkylglycerone 3-phosphate and alkylglycerol
CC       3-phosphate.
PR   PROSITE; PDOC00060;
DR   P40471, AYR1_YEAST ;
//
ID   1.1.1.102
DE   3-dehydrosphinganine reductase.
AN   3-ketosphinganine reductase.
AN   3-oxosphinganine reductase.
AN   3-oxosphinganine:NADPH oxidoreductase.
AN   D-3-dehydrosphinganine reductase.
AN   D-3-oxosphinganine reductase.
AN   D-3-oxosphinganine:B-NADPH oxidoreductase.
AN   DSR.
AN   KTS reductase.
CA   Sphinganine + NADP(+) = 3-dehydrosphinganine + NADPH.
DR   Q2KIJ5, KDSR_BOVIN ;  Q556J2, KDSR_DICDI ;  Q06136, KDSR_HUMAN ;
DR   Q6GV12, KDSR_MOUSE ;  Q758B6, TSC10_ASHGO;  Q59RQ2, TSC10_CANAL;
DR   Q6FQ42, TSC10_CANGA;  P0CR37, TSC10_CRYNB;  P0CR36, TSC10_CRYNJ;
DR   Q6BQK1, TSC10_DEBHA;  Q5BE65, TSC10_EMENI;  Q6CLN0, TSC10_KLULA;
DR   Q7RZR2, TSC10_NEUCR;  Q6CE86, TSC10_YARLI;  P38342, TSC10_YEAST;
//
ID   1.1.1.103
DE   L-threonine 3-dehydrogenase.
AN   TDH.
CA   L-threonine + NAD(+) = L-2-amino-3-oxobutanoate + NADH.
CC   -!- Acts in concert with EC 2.3.1.29 in the degradation of threonine to
CC       glycine.
CC   -!- This threonine-degradation pathway is common to prokaryotic and
CC       eukaryotic cells and the two enzymes involved form a complex.
CC   -!- In aqueous solution, the product L-2-amino-3-oxobutanoate can
CC       spontaneously decarboxylate to form aminoacetone.
PR   PROSITE; PDOC00058;
DR   A0KQV6, TDH_AERHH  ;  A4SHB7, TDH_AERS4  ;  B9J738, TDH_AGRRK  ;
DR   B6ESA4, TDH_ALISL  ;  B4S298, TDH_ALTMD  ;  B8J714, TDH_ANAD2  ;
DR   Q2IJN4, TDH_ANADE  ;  A7HEI5, TDH_ANADF  ;  B4UMJ1, TDH_ANASK  ;
DR   A7Z4X0, TDH_BACA2  ;  Q65JE7, TDH_BACLD  ;  O31776, TDH_BACSU  ;
DR   Q2KIR8, TDH_BOVIN  ;  B1YXP0, TDH_BURA4  ;  Q1BK24, TDH_BURCA  ;
DR   B1K269, TDH_BURCC  ;  A0B459, TDH_BURCH  ;  B4EFZ7, TDH_BURCJ  ;
DR   Q0B5Q1, TDH_BURCM  ;  A9AR24, TDH_BURM1  ;  A3MAC8, TDH_BURM7  ;
DR   A2RZW5, TDH_BURM9  ;  Q62EL5, TDH_BURMA  ;  A1UXP8, TDH_BURMS  ;
DR   A3P139, TDH_BURP0  ;  Q3JID4, TDH_BURP1  ;  A3NF91, TDH_BURP6  ;
DR   B2JPU0, TDH_BURP8  ;  B2T7X5, TDH_BURPP  ;  Q63PD9, TDH_BURPS  ;
DR   Q38ZS8, TDH_BURS3  ;  Q2T9E1, TDH_BURTA  ;  A4JKG7, TDH_BURVG  ;
DR   Q13SG2, TDH_BURXL  ;  Q7NXH5, TDH_CHRVO  ;  A8ARK6, TDH_CITK8  ;
DR   Q48AM4, TDH_COLP3  ;  B6J2S1, TDH_COXB2  ;  A9KET6, TDH_COXBN  ;
DR   A9NA21, TDH_COXBR  ;  Q83F39, TDH_COXBU  ;  C1D195, TDH_DEIDV  ;
DR   Q9RTU4, TDH_DEIRA  ;  A7ZTH0, TDH_ECO24  ;  B7ULH2, TDH_ECO27  ;
DR   B7MFI0, TDH_ECO45  ;  B7L742, TDH_ECO55  ;  Q8XEJ1, TDH_ECO57  ;
DR   B5YWB7, TDH_ECO5E  ;  B7NPC5, TDH_ECO7I  ;  B7N1S0, TDH_ECO81  ;
DR   B7M4A3, TDH_ECO8A  ;  C4ZXK8, TDH_ECOBW  ;  B1X950, TDH_ECODH  ;
DR   A8A681, TDH_ECOHS  ;  A1AHF3, TDH_ECOK1  ;  Q0TBJ0, TDH_ECOL5  ;
DR   Q8FCA2, TDH_ECOL6  ;  B1IZH4, TDH_ECOLC  ;  P07913, TDH_ECOLI  ;
DR   B7NES3, TDH_ECOLU  ;  B6I3J6, TDH_ECOSE  ;  B1LK55, TDH_ECOSM  ;
DR   Q1R4X4, TDH_ECOUT  ;  C5BB99, TDH_EDWI9  ;  A4W529, TDH_ENT38  ;
DR   A7MID0, TDH_ENTS8  ;  Q6DAT5, TDH_ERWCT  ;  B7LVH6, TDH_ESCF3  ;
DR   B0TYR8, TDH_FRAP2  ;  Q14IB6, TDH_FRAT1  ;  A7NDM9, TDH_FRATF  ;
DR   Q2A282, TDH_FRATH  ;  B2SDJ2, TDH_FRATM  ;  A0Q5K3, TDH_FRATN  ;
DR   Q0BKV5, TDH_FRATO  ;  Q5NGW4, TDH_FRATT  ;  A4IZ92, TDH_FRATW  ;
DR   Q5QUN8, TDH_IDILO  ;  B5XTI4, TDH_KLEP3  ;  A6TFL2, TDH_KLEP7  ;
DR   Q5X748, TDH_LEGPA  ;  A5IGK7, TDH_LEGPC  ;  Q5ZXM9, TDH_LEGPH  ;
DR   Q5WYJ7, TDH_LEGPL  ;  A6W1W3, TDH_MARMS  ;  Q11L77, TDH_MESSB  ;
DR   Q8K3F7, TDH_MOUSE  ;  Q6MD15, TDH_PARUW  ;  C6DIA7, TDH_PECCP  ;
DR   Q7MY48, TDH_PHOLL  ;  Q6LRD9, TDH_PHOPR  ;  Q8MIR0, TDH_PIG    ;
DR   Q6AAR3, TDH_PROAC  ;  B4F134, TDH_PROMH  ;  Q15ZU4, TDH_PSEA6  ;
DR   Q3IHW0, TDH_PSEHT  ;  A1SVW5, TDH_PSYIN  ;  Q9UYX0, TDH_PYRAB  ;
DR   Q8U259, TDH_PYRFU  ;  O58389, TDH_PYRHO  ;  Q5JI69, TDH_PYRKO  ;
DR   B3PUI4, TDH_RHIE6  ;  Q2K618, TDH_RHIEC  ;  Q1MDT5, TDH_RHIL3  ;
DR   Q983J7, TDH_RHILO  ;  B5ZXE7, TDH_RHILW  ;  Q52998, TDH_RHIME  ;
DR   C3MFH1, TDH_RHISN  ;  A4FND4, TDH_SACEN  ;  B5EXC3, TDH_SALA4  ;
DR   A9MKQ8, TDH_SALAR  ;  Q57IC5, TDH_SALCH  ;  B5FLI6, TDH_SALDC  ;
DR   B5R5E1, TDH_SALEP  ;  B5RGH0, TDH_SALG2  ;  B4T9A1, TDH_SALHS  ;
DR   B4SXB9, TDH_SALNS  ;  Q5PC07, TDH_SALPA  ;  A9MVL0, TDH_SALPB  ;
DR   C0Q1V0, TDH_SALPC  ;  B5BHZ1, TDH_SALPK  ;  B4TZV9, TDH_SALSV  ;
DR   Q8Z2F4, TDH_SALTI  ;  Q8ZL52, TDH_SALTY  ;  A8GLC6, TDH_SERP5  ;
DR   A1S1Q3, TDH_SHEAM  ;  B8EDS6, TDH_SHEB2  ;  A3CYN0, TDH_SHEB5  ;
DR   A6WUG6, TDH_SHEB8  ;  A9KWY0, TDH_SHEB9  ;  Q07W50, TDH_SHEFN  ;
DR   B0TNM4, TDH_SHEHH  ;  A3QJC8, TDH_SHELP  ;  Q8E8J1, TDH_SHEON  ;
DR   A8GYP8, TDH_SHEPA  ;  A4YCC5, TDH_SHEPC  ;  A0L2Q3, TDH_SHESA  ;
DR   A8FPE0, TDH_SHESH  ;  Q0HDA3, TDH_SHESM  ;  Q0HPI5, TDH_SHESR  ;
DR   A1RE07, TDH_SHESW  ;  B1KL24, TDH_SHEWM  ;  B2U5D5, TDH_SHIB3  ;
DR   Q31V06, TDH_SHIBS  ;  Q329N8, TDH_SHIDS  ;  Q0SYE5, TDH_SHIF8  ;
DR   P59409, TDH_SHIFL  ;  Q3YVY1, TDH_SHISS  ;  Q5LN53, TDH_SILPO  ;
DR   A6UBM6, TDH_SINMW  ;  Q02BT1, TDH_SOLUE  ;  Q82MN2, TDH_STRAW  ;
DR   Q9L233, TDH_STRCO  ;  B1VWE7, TDH_STRGG  ;  B2FQN4, TDH_STRMK  ;
DR   Q67N85, TDH_SYMTH  ;  B6YTJ5, TDH_THEON  ;  Q72L62, TDH_THET2  ;
DR   Q5SKS4, TDH_THET8  ;  Q8R7K0, TDH_THETN  ;  A5F0N6, TDH_VIBC3  ;
DR   Q9KL62, TDH_VIBCH  ;  C3LWF0, TDH_VIBCM  ;  Q5E0F9, TDH_VIBF1  ;
DR   B5ETJ6, TDH_VIBFM  ;  P59410, TDH_VIBPA  ;  B7VR52, TDH_VIBSL  ;
DR   Q8D442, TDH_VIBVU  ;  Q7MFL5, TDH_VIBVY  ;  Q8PNN2, TDH_XANAC  ;
DR   Q3BWT0, TDH_XANC5  ;  Q4URI9, TDH_XANC8  ;  B0RU31, TDH_XANCB  ;
DR   O34268, TDH_XANCP  ;  Q2NZP2, TDH_XANOM  ;  Q5GWI3, TDH_XANOR  ;
DR   A1JHX8, TDH_YERE8  ;  A7FCU5, TDH_YERP3  ;  Q1C278, TDH_YERPA  ;
DR   B2JYP4, TDH_YERPB  ;  Q8ZJN2, TDH_YERPE  ;  A9R685, TDH_YERPG  ;
DR   Q1CD13, TDH_YERPN  ;  A4TSC6, TDH_YERPP  ;  Q66GC5, TDH_YERPS  ;
DR   B1JQW2, TDH_YERPY  ;
//
ID   1.1.1.104
DE   4-oxoproline reductase.
AN   Hydroxyproline oxidase.
CA   4-hydroxy-L-proline + NAD(+) = 4-oxoproline + NADH.
//
ID   1.1.1.105
DE   Retinol dehydrogenase.
CA   Retinol + NAD(+) = retinal + NADH.
PR   PROSITE; PDOC00060;
DR   Q3T001, H17B6_BOVIN;  O14756, H17B6_HUMAN;  Q9R092, H17B6_MOUSE;
DR   O54753, H17B6_RAT  ;  Q27979, RDH1_BOVIN ;  Q92781, RDH1_HUMAN ;
DR   P50170, RDH2_RAT   ;  P50169, RDH3_RAT   ;  O88451, RDH7_MOUSE ;
DR   P55006, RDH7_RAT   ;  Q8N3Y7, RDHE2_HUMAN;  Q7TQA3, RDHE2_MOUSE;
//
ID   1.1.1.106
DE   Pantoate 4-dehydrogenase.
AN   Panthothenase.
CA   (R)-pantoate + NAD(+) = (R)-4-dehydropantoate + NADH.
//
ID   1.1.1.107
DE   Pyridoxal 4-dehydrogenase.
CA   Pyridoxal + NAD(+) = 4-pyridoxolactone + NADH.
CC   -!- The enzyme acts on the hemiacetal form of the substrate.
DR   Q988B7, PLDH_RHILO ;  Q76KC2, PLD_MICLT  ;
//
ID   1.1.1.108
DE   Carnitine 3-dehydrogenase.
CA   Carnitine + NAD(+) = 3-dehydrocarnitine + NADH.
//
ID   1.1.1.109
DE   Transferred entry: 1.3.1.28.
//
ID   1.1.1.110
DE   Indolelactate dehydrogenase.
AN   Indole-3-lactate dehydrogenase.
CA   (Indol-3-yl)lactate + NAD(+) = (indol-3-yl)pyruvate + NADH.
//
ID   1.1.1.111
DE   3-(imidazol-5-yl)lactate dehydrogenase.
CA   (S)-3-(imidazol-5-yl)lactate + NAD(P)(+) = 3-(imidazol-5-yl)pyruvate +
CA   NAD(P)H.
//
ID   1.1.1.112
DE   Indanol dehydrogenase.
CA   Indan-1-ol + NAD(P)(+) = indanone + NAD(P)H.
CC   -!- 3(20)-alpha-hydroxysteroids are also oxidized, more slowly.
DR   Q04828, AK1C1_HUMAN;  Q95JH7, AK1C1_MACFA;  Q95JH6, AK1C1_MACFU;
DR   Q5REQ0, AK1C1_PONAB;  P42330, AK1C3_HUMAN;  Q5R7C9, AK1C3_PONAB;
//
ID   1.1.1.113
DE   L-xylose 1-dehydrogenase.
CA   L-xylose + NADP(+) = L-xylono-1,4-lactone + NADPH.
CC   -!- Also oxidizes D-arabinose and D-lyxose.
//
ID   1.1.1.114
DE   Apiose 1-reductase.
AN   D-apiitol reductase.
AN   D-apiose reductase.
CA   D-apiitol + NAD(+) = D-apiose + NADH.
//
ID   1.1.1.115
DE   Ribose 1-dehydrogenase (NADP(+)).
AN   NADP-pentose-dehydrogenase.
CA   D-ribose + NADP(+) + H(2)O = D-ribonate + NADPH.
CC   -!- Also acts, more slowly, on D-xylose and other pentoses.
//
ID   1.1.1.116
DE   D-arabinose 1-dehydrogenase.
CA   D-arabinose + NAD(+) = D-arabinono-1,4-lactone + NADH.
DR   Q04212, ARA2_YEAST ;
//
ID   1.1.1.117
DE   D-arabinose 1-dehydrogenase (NAD(P)(+)).
CA   D-arabinose + NAD(P)(+) = D-arabinono-1,4-lactone + NAD(P)H.
CC   -!- Also acts on L-galactose, 6-deoxy- and 3,6-dideoxy-L-galactose.
DR   P38115, ARA1_YEAST ;
//
ID   1.1.1.118
DE   Glucose 1-dehydrogenase (NAD(+)).
CA   D-glucose + NAD(+) = D-glucono-1,5-lactone + NADH.
//
ID   1.1.1.119
DE   Glucose 1-dehydrogenase (NADP(+)).
CA   D-glucose + NADP(+) = D-glucono-1,5-lactone + NADPH.
CC   -!- Also oxidizes D-mannose, 2-deoxy-D-glucose and 2-amino-2-deoxy-D-
CC       mannose.
//
ID   1.1.1.120
DE   Galactose 1-dehydrogenase (NADP(+)).
CA   D-galactose + NADP(+) = D-galactonolactone + NADPH.
CC   -!- Also acts on L-arabinose, 6-deoxy- and 2-deoxy-D-galactose.
//
ID   1.1.1.121
DE   Aldose 1-dehydrogenase.
CA   D-aldose + NAD(+) = D-aldonolactone + NADH.
CC   -!- Acts on D-glucose, 2-deoxy- and 6-deoxy-D-glucose, D-galactose,
CC       6-deoxy-D-galactose, 2-deoxy-L-arabinose and D-xylose.
//
ID   1.1.1.122
DE   D-threo-aldose 1-dehydrogenase.
AN   (2S,3R)-aldose dehydrogenase.
AN   L-fucose dehydrogenase.
CA   A D-threo-aldose + NAD(+) = a D-threo-aldono-1,5-lactone + NADH.
CC   -!- Acts on L-fucose, D-arabinose and L-xylose.
CC   -!- The animal enzyme was also shown to act on L-arabinose, and the
CC       enzyme from Pseudomonas caryophylli on L-glucose.
//
ID   1.1.1.123
DE   Sorbose 5-dehydrogenase (NADP(+)).
AN   5-ketofructose reductase.
CA   L-sorbose + NADP(+) = 5-dehydro-D-fructose + NADPH.
//
ID   1.1.1.124
DE   Fructose 5-dehydrogenase (NADP(+)).
AN   5-ketofructose reductase (NADP(+)).
AN   5-ketofructose reductase (NADP+).
CA   D-fructose + NADP(+) = 5-dehydro-D-fructose + NADPH.
DR   P19574, DHF5_ERWCI ;
//
ID   1.1.1.125
DE   2-deoxy-D-gluconate 3-dehydrogenase.
AN   2-keto-3-deoxygluconate oxidoreductase.
CA   2-deoxy-D-gluconate + NAD(+) = 3-dehydro-2-deoxy-D-gluconate + NADH.
PR   PROSITE; PDOC00060;
//
ID   1.1.1.126
DE   2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase.
AN   2-keto-3-deoxy-D-gluconate dehydrogenase.
CA   2-dehydro-3-deoxy-D-gluconate + NADP(+) = (4S,5S)-4,5-dihydroxy-2,6-
CA   dioxohexanoate + NADPH.
//
ID   1.1.1.127
DE   2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase.
AN   2-keto-3-deoxygluconate dehydrogenase.
CA   2-dehydro-3-deoxy-D-gluconate + NAD(+) = (4S)-4,6-dihydroxy-2,5-
CA   dioxohexanoate + NADH.
CC   -!- The enzyme from Pseudomonas acts equally well on NAD(+) or NADP(+),
CC       while those from Erwinia chrysanthemi and Escherichia coli are more
CC       specific for NAD(+).
DR   P50842, KDUD_BACSU ;  Q05528, KDUD_DICD3 ;  P37769, KDUD_ECOLI ;
//
ID   1.1.1.128
DE   L-idonate 2-dehydrogenase.
AN   5-ketogluconate 2-reductase.
CA   L-idonate + NADP(+) = 5-dehydro-D-gluconate + NADPH.
PR   PROSITE; PDOC00058;
//
ID   1.1.1.129
DE   L-threonate 3-dehydrogenase.
AN   L-threonic acid dehydrogenase.
CA   L-threonate + NAD(+) = 3-dehydro-L-threonate + NADH.
//
ID   1.1.1.130
DE   3-dehydro-L-gulonate 2-dehydrogenase.
AN   2,3-diketo-L-gulonate reductase.
AN   3-keto-L-gulonate dehydrogenase.
CA   3-dehydro-L-gulonate + NAD(P)(+) = (4R,5S)-4,5,6-trihydroxy-2,3-
CA   dioxohexanoate + NAD(P)H.
DR   A8ARG3, DLGD_CITK8 ;  A7ZTC2, DLGD_ECO24 ;  B7ULD6, DLGD_ECO27 ;
DR   B7MFE1, DLGD_ECO45 ;  B7L6Z1, DLGD_ECO55 ;  B7NP75, DLGD_ECO7I ;
DR   B7N223, DLGD_ECO81 ;  B7M3J9, DLGD_ECO8A ;  C4ZXG6, DLGD_ECOBW ;
DR   B1X8J1, DLGD_ECODH ;  A8A634, DLGD_ECOHS ;  A1AHB7, DLGD_ECOK1 ;
DR   Q0TBM6, DLGD_ECOL5 ;  Q8FCD6, DLGD_ECOL6 ;  B1IZL7, DLGD_ECOLC ;
DR   P37672, DLGD_ECOLI ;  B7NEM8, DLGD_ECOLU ;  B6I3E8, DLGD_ECOSE ;
DR   B1LJD7, DLGD_ECOSM ;  Q1R519, DLGD_ECOUT ;  B7LTI6, DLGD_ESCF3 ;
DR   A5UIG1, DLGD_HAEIG ;  P44995, DLGD_HAEIN ;  Q93Q64, DLGD_KLEOX ;
DR   B5XMX0, DLGD_KLEP3 ;  Q65WJ9, DLGD_MANSM ;  Q9CLH5, DLGD_PASMU ;
DR   B5EX79, DLGD_SALA4 ;  B5FLE5, DLGD_SALDC ;  B5R4Q5, DLGD_SALEP ;
DR   B4T959, DLGD_SALHS ;  B4SWL6, DLGD_SALNS ;  Q5PLN6, DLGD_SALPA ;
DR   A9MUW2, DLGD_SALPB ;  C0Q1C9, DLGD_SALPC ;  B5BHV4, DLGD_SALPK ;
DR   B4TZ64, DLGD_SALSV ;  Q8Z2C5, DLGD_SALTI ;  Q8ZL83, DLGD_SALTY ;
DR   Q31V43, DLGD_SHIBS ;  Q83PQ6, DLGD_SHIFL ;
//
ID   1.1.1.131
DE   Mannuronate reductase.
AN   Mannonate dehydrogenase.
CA   D-mannonate + NAD(P)(+) = D-mannuronate + NAD(P)H.
CC   -!- Formerly EC 1.1.1.180 and EC 1.2.1.34.
//
ID   1.1.1.132
DE   GDP-mannose 6-dehydrogenase.
CA   GDP-D-mannose + 2 NAD(+) + H(2)O = GDP-D-mannuronate + 2 NADH.
CC   -!- Also uses the corresponding deoxynucleoside diphosphate derivative as
CC       a substrate.
DR   P51585, ALGD_AZOVI ;  P11759, ALGD_PSEAE ;  Q88NC4, ALGD_PSEPK ;
DR   O07299, ALGD_PSESH ;  Q887P8, ALGD_PSESM ;  P59793, ALGD_PSESY ;
//
ID   1.1.1.133
DE   dTDP-4-dehydrorhamnose reductase.
AN   dTDP-4-keto-L-rhamnose reductase.
AN   dTDP-6-deoxy-L-mannose dehydrogenase.
CA   dTDP-6-deoxy-L-mannose + NADP(+) = dTDP-4-dehydro-6-deoxy-L-mannose +
CA   NADPH.
CC   -!- In the reverse direction, reduction on the 4-position of the hexose
CC       moiety takes place only while the substrate is bound to another
CC       enzyme that catalyzes epimerization at C-3 and C-5; the complex has
CC       been referred to as dTDP-L-rhamnose synthase.
DR   P37760, RMLD_ECOLI ;  Q46769, RMLD_ECOLX ;  A0QTF8, RMLD_MYCS2 ;
DR   P96871, RMLD_MYCTU ;  P55463, RMLD_RHISN ;  P26392, RMLD_SALTY ;
DR   P37778, RMLD_SHIFL ;  P29781, RMLD_STRGR ;
//
ID   1.1.1.134
DE   dTDP-6-deoxy-L-talose 4-dehydrogenase.
CA   dTDP-6-deoxy-L-talose + NADP(+) = dTDP-4-dehydro-6-deoxy-L-mannose +
CA   NADPH.
CC   -!- Oxidation on the 4-position of the hexose moiety takes place only
CC       while the substrate is bound to another enzyme that catalyzes
CC       epimerization at C-3 and C-5.
//
ID   1.1.1.135
DE   GDP-6-deoxy-D-talose 4-dehydrogenase.
CA   GDP-6-deoxy-D-talose + NAD(P)(+) = GDP-4-dehydro-6-deoxy-D-mannose +
CA   NAD(P)H.
//
ID   1.1.1.136
DE   UDP-N-acetylglucosamine 6-dehydrogenase.
CA   UDP-N-acetyl-D-glucosamine + 2 NAD(+) + H(2)O = UDP-N-acetyl-2-amino-2-
CA   deoxy-D-glucuronate + 2 NADH.
//
ID   1.1.1.137
DE   Ribitol-5-phosphate 2-dehydrogenase.
CA   D-ribitol 5-phosphate + NAD(P)(+) = D-ribulose 5-phosphate + NAD(P)H.
DR   Q8RKJ0, TARJ_BACPZ ;
//
ID   1.1.1.138
DE   Mannitol 2-dehydrogenase (NADP(+)).
AN   NADP-dependent mannitol dehydrogenase.
CA   D-mannitol + NADP(+) = D-fructose + NADPH.
PR   PROSITE; PDOC00060;
DR   O93868, MTDH_AGABI ;  P0C0Y4, MTDH_ALTAL ;  P0C0Y5, MTDH_DAVTA ;
DR   O00058, MTDH_UROFA ;
//
ID   1.1.1.139
DE   Transferred entry: 1.1.1.21.
//
ID   1.1.1.140
DE   Sorbitol-6-phosphate 2-dehydrogenase.
AN   Glucitol-6-phosphate dehydrogenase.
AN   Ketosephosphate reductase.
CA   D-sorbitol 6-phosphate + NAD(+) = D-fructose 6-phosphate + NADH.
PR   PROSITE; PDOC00060;
DR   P37079, SORD_KLEPN ;  P05707, SRLD_ECOLI ;
//
ID   1.1.1.141
DE   15-hydroxyprostaglandin dehydrogenase (NAD(+)).
AN   15-hydroxyprostaglandin dehydrogenase.
CA   (5Z,13E,15S)-11-alpha,15-dihydroxy-9-oxoprost-5,13-dienoate + NAD(+) =
CA   (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-5,13-dienoate + NADH.
CC   -!- Acts on prostaglandins E(2), F(2-alpha) and B(1), but not on
CC       prostaglandin D(2) (cf. EC 1.1.1.196 and EC 1.1.1.197).
PR   PROSITE; PDOC00060;
DR   Q3T0C2, PGDH_BOVIN ;  P70684, PGDH_CAVPO ;  P15428, PGDH_HUMAN ;
DR   Q8MJY8, PGDH_MACFA ;  Q8VCC1, PGDH_MOUSE ;  O08699, PGDH_RAT   ;
//
ID   1.1.1.142
DE   D-pinitol dehydrogenase.
CA   1D-3-O-methyl-chiro-inositol + NADP(+) = 2D-5-O-methyl-2,3,5/4,6-
CA   pentahydroxycyclohexanone + NADPH.
//
ID   1.1.1.143
DE   Sequoyitol dehydrogenase.
CA   5-O-methyl-myo-inositol + NAD(+) = 2D-5-O-methyl-2,3,5/4,6-
CA   pentahydroxycyclohexanone + NADH.
//
ID   1.1.1.144
DE   Perillyl-alcohol dehydrogenase.
CA   Perillyl alcohol + NAD(+) = perillyl aldehyde + NADH.
CC   -!- Oxidizes a number of primary alcohols with the alcohol group allylic
CC       to an endocyclic double bond and a 6-membered ring, either aromatic
CC       or hydroaromatic.
DR   O85057, LIHY_GEOSE ;
//
ID   1.1.1.145
DE   3-beta-hydroxy-Delta(5)-steroid dehydrogenase.
AN   3-beta-hydroxy-5-ene steroid dehydrogenase.
AN   Progesterone reductase.
CA   A 3-beta-hydroxy-Delta(5)-steroid + NAD(+) = a 3-oxo-Delta(5)-steroid +
CA   NADH.
CC   -!- Acts on 3-beta-hydroxyandrost-5-en-17-one to form androst-4-ene-3,17-
CC       dione and on 3-beta-hydroxypregn-5-en-20-one to form progesterone.
DR   P14060, 3BHS1_HUMAN;  P27365, 3BHS1_MACMU;  Q60555, 3BHS1_MESAU;
DR   P24815, 3BHS1_MOUSE;  P22071, 3BHS1_RAT  ;  P26439, 3BHS2_HUMAN;
DR   Q64421, 3BHS2_MESAU;  P26149, 3BHS2_MOUSE;  P22072, 3BHS2_RAT  ;
DR   P26150, 3BHS3_MOUSE;  Q62878, 3BHS4_RAT  ;  O35469, 3BHS6_MOUSE;
DR   P14893, 3BHS_BOVIN ;  Q5IFP1, 3BHS_CANFA ;  Q67477, 3BHS_FOWPN ;
DR   O46516, 3BHS_HORSE ;  O53454, 3BHS_MYCTU ;  Q9N119, 3BHS_PIG   ;
DR   O57245, 3BHS_VACCA ;  P21097, 3BHS_VACCC ;  P26670, 3BHS_VACCW ;
DR   Q89187, 3BHS_VAR67 ;
//
ID   1.1.1.146
DE   11-beta-hydroxysteroid dehydrogenase.
AN   Corticosteroid 11-beta-dehydrogenase.
CA   An 11-beta-hydroxysteroid + NADP(+) = an 11-oxosteroid + NADPH.
PR   PROSITE; PDOC00060;
DR   Q6QLL4, DHI1_CAVPO ;  P28845, DHI1_HUMAN ;  Q6R0J2, DHI1_MESAU ;
DR   P50172, DHI1_MOUSE ;  Q7M3I4, DHI1_RABIT ;  P16232, DHI1_RAT   ;
DR   Q29608, DHI1_SAISC ;  P51975, DHI1_SHEEP ;
//
ID   1.1.1.147
DE   16-alpha-hydroxysteroid dehydrogenase.
CA   A 16-alpha-hydroxysteroid + NAD(P)(+) = a 16-oxosteroid + NAD(P)H.
//
ID   1.1.1.148
DE   Estradiol 17-alpha-dehydrogenase.
CA   Estradiol-17-alpha + NAD(P)(+) = estrone + NAD(P)H.
//
ID   1.1.1.149
DE   20-alpha-hydroxysteroid dehydrogenase.
CA   17-alpha,20-alpha-dihydroxypregn-4-en-3-one + NAD(P)(+) = 17-alpha-
CA   hydroxyprogesterone + NAD(P)H.
CC   -!- A-specific with respect to NAD(P)(+) (cf. EC 1.1.1.62).
PR   PROSITE; PDOC00061;
DR   P35430, AHD2_TETPY ;  Q04828, AK1C1_HUMAN;  Q95JH7, AK1C1_MACFA;
DR   Q95JH6, AK1C1_MACFU;  Q5REQ0, AK1C1_PONAB;  Q8K023, AKC1H_MOUSE;
DR   P51652, AKC1H_RAT  ;  P16116, ALDR_BOVIN ;  P80508, PE2R_RABIT ;
//
ID   1.1.1.150
DE   21-hydroxysteroid dehydrogenase (NAD(+)).
CA   Pregnan-21-ol + NAD(+) = pregnan-21-al + NADH.
CC   -!- Acts on a number of 21-hydroxycorticosteroids.
//
ID   1.1.1.151
DE   21-hydroxysteroid dehydrogenase (NADP(+)).
AN   21-hydroxy steroid (nicotinamide adenine dinucleotide phosphate)
AN   dehydrogenase.
AN   21-hydroxy steroid dehydrogenase.
AN   21-hydroxy steroid dehydrogenase (nicotinamide adenine dinucleotide
AN   phosphate).
AN   NADP-21-hydroxysteroid dehydrogenase.
CA   Pregnan-21-ol + NADP(+) = pregnan-21-al + NADPH.
CC   -!- Acts on a number of 21-hydroxycorticosteroids.
//
ID   1.1.1.152
DE   3-alpha-hydroxy-5-beta-androstane-17-one 3-alpha-dehydrogenase.
AN   Etiocholanolone 3-alpha-dehydrogenase.
CA   3-alpha-hydroxy-5-beta-androstane-17-one + NAD(+) = 5-beta-androstane-
CA   3,17-dione + NADH.
//
ID   1.1.1.153
DE   Sepiapterin reductase.
CA   (1) 7,8-dihydrobiopterin + NADP(+) = sepiapterin + NADPH.
CA   (2) Tetrahydrobiopterin + 2 NADP(+) = 6-pyruvoyl-5,6,7,8-tetrahydropterin
CA   + 2 NADPH.
CC   -!- Catalyzes the final step in the de novo synthesis of
CC       tetrahydrobiopterin from GTP, with the other enzymes involved being
CC       EC 3.5.4.16 and EC 4.2.3.12.
DR   Q17QK8, SPRE_BOVIN ;  Q54GP3, SPRE_DICDI ;  P35270, SPRE_HUMAN ;
DR   Q8R536, SPRE_MERUN ;  Q64105, SPRE_MOUSE ;  P18297, SPRE_RAT   ;
DR   Q7ZY31, SPRE_XENLA ;  B0BML7, SPRE_XENTR ;
//
ID   1.1.1.154
DE   Ureidoglycolate dehydrogenase.
CA   (S)-ureidoglycolate + NAD(P)(+) = oxalureate + NAD(P)H.
DR   P58408, ALLD_ECO57 ;  P77555, ALLD_ECOLI ;
//
ID   1.1.1.155
DE   Transferred entry: 1.1.1.87.
//
ID   1.1.1.156
DE   Glycerol 2-dehydrogenase (NADP(+)).
AN   Dihydroxyacetone reductase.
CA   Glycerol + NADP(+) = glycerone + NADPH.
//
ID   1.1.1.157
DE   3-hydroxybutyryl-CoA dehydrogenase.
AN   Beta-hydroxybutyryl-CoA dehydrogenase.
AN   BHBD.
CA   (S)-3-hydroxybutanoyl-CoA + NADP(+) = 3-acetoacetyl-CoA + NADPH.
PR   PROSITE; PDOC00065;
DR   O53753, FADB2_MYCTU;  P45856, HBD_BACSU  ;  Q45223, HBD_BRAJA  ;
DR   P52041, HBD_CLOAB  ;  P45364, HBD_CLODI  ;  P81343, HBD_CLOPA  ;
DR   Q9RVG1, HBD_DEIRA  ;  P77851, HBD_THETC  ;  P76083, PAAH_ECOLI ;
//
ID   1.1.1.158
DE   UDP-N-acetylmuramate dehydrogenase.
AN   UDP-GlcNAc-enoylpyruvate reductase.
AN   UDP-N-acetylenolpyruvoylglucosamine reductase.
AN   UDP-N-acetylglucosamine-enoylpyruvate reductase.
AN   Uridine diphospho-N-acetylglucosamine-enolpyruvate reductase.
AN   Uridine diphosphoacetylpyruvoylglucosamine reductase.
AN   Uridine-5'-diphospho-N-acetyl-2-amino-2-deoxy-3-O-lactylglucose:NADP-
AN   oxidoreductase.
CA   UDP-N-acetylmuramate + NADP(+) = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-
CA   glucosamine + NADPH.
CF   FAD.
CC   -!- Sodium dithionite, sodium borohydride and, to a lesser extent, NADH
CC       can replace NADPH.
DR   Q81WD1, MURB1_BACAN;  Q732F9, MURB1_BACC1;  Q819Q4, MURB1_BACCR;
DR   Q636B7, MURB1_BACCZ;  Q6HEQ5, MURB1_BACHK;  Q8NTF4, MURB1_CORGL;
DR   Q67RL6, MURB1_SYMTH;  Q81XC5, MURB2_BACAN;  Q72Y09, MURB2_BACC1;
DR   Q815R9, MURB2_BACCR;  Q631P8, MURB2_BACCZ;  Q6HBI9, MURB2_BACHK;
DR   Q8NTB0, MURB2_CORGL;  Q67Q47, MURB2_SYMTH;  B0CCD5, MURB_ACAM1 ;
DR   Q6FAZ1, MURB_ACIAD ;  B0VRK7, MURB_ACIBS ;  B0V744, MURB_ACIBY ;
DR   A5FUL2, MURB_ACICJ ;  B9JH49, MURB_AGRRK ;  Q8UDN0, MURB_AGRT5 ;
DR   B9JY52, MURB_AGRVS ;  Q0VQP1, MURB_ALCBS ;  Q0A6K4, MURB_ALHEH ;
DR   A6TVF6, MURB_ALKMQ ;  A8MLW8, MURB_ALKOO ;  B3ETU4, MURB_AMOA5 ;
DR   B8J8F0, MURB_ANAD2 ;  Q2IG34, MURB_ANADE ;  A7HH69, MURB_ANADF ;
DR   B9KIR5, MURB_ANAMF ;  Q5PAK9, MURB_ANAMM ;  B4UES3, MURB_ANASK ;
DR   B9MN03, MURB_ANATD ;  Q3MAP7, MURB_ANAVT ;  B7GGI1, MURB_ANOFW ;
DR   O66805, MURB_AQUAE ;  Q5P3R2, MURB_AROAE ;  A8HZA5, MURB_AZOC5 ;
DR   A1KBU9, MURB_AZOSB ;  A7Z4E6, MURB_BACA2 ;  Q5LBG5, MURB_BACFN ;
DR   Q64RZ8, MURB_BACFR ;  Q9K9T1, MURB_BACHD ;  Q65JX9, MURB_BACLD ;
DR   Q45305, MURB_BACLI ;  A8FCY2, MURB_BACP2 ;  Q5WAV8, MURB_BACSK ;
DR   P18579, MURB_BACSU ;  Q8A806, MURB_BACTN ;  A1UTC3, MURB_BARBK ;
DR   Q6G2Q7, MURB_BARHE ;  Q6G126, MURB_BARQU ;  A9IWA3, MURB_BART1 ;
DR   P61433, MURB_BDEBA ;  B2IGG2, MURB_BEII9 ;  Q7VQF2, MURB_BLOFL ;
DR   Q493L3, MURB_BLOPB ;  Q7WGH4, MURB_BORBR ;  O51544, MURB_BORBU ;
DR   Q660S4, MURB_BORGA ;  Q7W509, MURB_BORPA ;  Q9X6Y8, MURB_BORPE ;
DR   Q89FU9, MURB_BRAJA ;  A5EPK0, MURB_BRASB ;  A4YZK1, MURB_BRASO ;
DR   B2S6Q2, MURB_BRUA1 ;  Q2YLY7, MURB_BRUA2 ;  Q57C80, MURB_BRUAB ;
DR   A9M688, MURB_BRUC2 ;  C0RE68, MURB_BRUMB ;  Q8YI64, MURB_BRUME ;
DR   A5VRH5, MURB_BRUO2 ;  B0CHL8, MURB_BRUSI ;  Q8FZP4, MURB_BRUSU ;
DR   P57153, MURB_BUCAI ;  Q8KA63, MURB_BUCAP ;  P59450, MURB_BUCBP ;
DR   B1YVE7, MURB_BURA4 ;  Q1BU59, MURB_BURCA ;  B1JXG4, MURB_BURCC ;
DR   A0K9X7, MURB_BURCH ;  Q0BCG5, MURB_BURCM ;  A9AGJ5, MURB_BURM1 ;
DR   A3MHG6, MURB_BURM7 ;  A2S948, MURB_BURM9 ;  Q62M77, MURB_BURMA ;
DR   A1V1B7, MURB_BURMS ;  A3NS80, MURB_BURP0 ;  Q3JVB9, MURB_BURP1 ;
DR   A3N6J6, MURB_BURP6 ;  B2JDU4, MURB_BURP8 ;  B2SY64, MURB_BURPP ;
DR   Q63WM3, MURB_BURPS ;  Q39DI6, MURB_BURS3 ;  Q2T0L2, MURB_BURTA ;
DR   A4JH86, MURB_BURVG ;  Q13UR0, MURB_BURXL ;  A4XIM9, MURB_CALS8 ;
DR   Q9PM01, MURB_CAMJE ;  Q5HSB7, MURB_CAMJR ;  Q3AAE8, MURB_CARHZ ;
DR   B8H085, MURB_CAUCN ;  Q9A5A7, MURB_CAUCR ;  B0T826, MURB_CAUSK ;
DR   A9WG69, MURB_CHLAA ;  Q5L5A3, MURB_CHLAB ;  B8G5Y4, MURB_CHLAD ;
DR   Q822B0, MURB_CHLCV ;  Q255M5, MURB_CHLFF ;  Q9PL89, MURB_CHLMU ;
DR   Q9Z6S1, MURB_CHLPN ;  B9LKI9, MURB_CHLSY ;  B0B960, MURB_CHLT2 ;
DR   B3QWU0, MURB_CHLT3 ;  Q3KKK8, MURB_CHLTA ;  B0BAT9, MURB_CHLTB ;
DR   P0CD77, MURB_CHLTR ;  Q7NXN4, MURB_CHRVO ;  Q97LP4, MURB_CLOAB ;
DR   A7FYX2, MURB_CLOB1 ;  C3KV11, MURB_CLOB6 ;  A6M2Y4, MURB_CLOB8 ;
DR   B2UZY4, MURB_CLOBA ;  B2TQS2, MURB_CLOBB ;  A5I7A3, MURB_CLOBH ;
DR   C1FMJ6, MURB_CLOBJ ;  B1IFW4, MURB_CLOBK ;  A7GIX4, MURB_CLOBL ;
DR   B1L271, MURB_CLOBM ;  Q180P9, MURB_CLOD6 ;  B9DWV2, MURB_CLOK1 ;
DR   A5N360, MURB_CLOK5 ;  A0PYB4, MURB_CLONN ;  Q0TU88, MURB_CLOP1 ;
DR   Q8XNI0, MURB_CLOPE ;  A9KSS3, MURB_CLOPH ;  Q0SW37, MURB_CLOPS ;
DR   Q890Y6, MURB_CLOTE ;  A3DBM4, MURB_CLOTH ;  Q47UY2, MURB_COLP3 ;
DR   P61434, MURB_CORDI ;  A4QB37, MURB_CORGB ;  Q4JSV7, MURB_CORJK ;
DR   B6J5K1, MURB_COXB1 ;  B6J2Q1, MURB_COXB2 ;  A9KER1, MURB_COXBN ;
DR   A9NA46, MURB_COXBR ;  Q83F16, MURB_COXBU ;  Q46XL1, MURB_CUPPJ ;
DR   Q47K28, MURB_DECAR ;  Q1IXV7, MURB_DEIGD ;  Q9RWN8, MURB_DEIRA ;
DR   Q313Q1, MURB_DESDG ;  A8ZXW1, MURB_DESOH ;  Q6AJ55, MURB_DESPS ;
DR   A4J2B3, MURB_DESRM ;  Q728V0, MURB_DESVH ;  A8LS61, MURB_DINSH ;
DR   Q8X711, MURB_ECO57 ;  Q8FB88, MURB_ECOL6 ;  P08373, MURB_ECOLI ;
DR   Q830P3, MURB_ENTFA ;  Q6DAP0, MURB_ERWCT ;  Q2NCY8, MURB_ERYLH ;
DR   C4ZEG7, MURB_EUBR3 ;  B1YJK3, MURB_EXIS2 ;  A7HJQ1, MURB_FERNB ;
DR   A5FNG4, MURB_FLAJ1 ;  Q5NFD4, MURB_FRATT ;  Q8RDQ3, MURB_FUSNN ;
DR   Q5L1H7, MURB_GEOKA ;  B3E3Y0, MURB_GEOLS ;  Q39YL7, MURB_GEOMG ;
DR   B9M174, MURB_GEOSF ;  P61435, MURB_GEOSL ;  A4ILI2, MURB_GEOTN ;
DR   A5G8J8, MURB_GEOUR ;  Q7NI66, MURB_GLOVI ;  Q5FUJ3, MURB_GLUOX ;
DR   Q0BV27, MURB_GRABC ;  Q7VPJ2, MURB_HAEDU ;  Q4QNS0, MURB_HAEI8 ;
DR   P44605, MURB_HAEIN ;  Q7VJ12, MURB_HELHP ;  B0TGC2, MURB_HELMI ;
DR   Q9ZJJ4, MURB_HELPJ ;  O25963, MURB_HELPY ;  Q0C566, MURB_HYPNA ;
DR   Q5QY76, MURB_IDILO ;  Q28NP1, MURB_JANSC ;  Q5FL42, MURB_LACAC ;
DR   Q03SJ8, MURB_LACBA ;  Q1GB18, MURB_LACDA ;  Q04BG3, MURB_LACDB ;
DR   B2GAN2, MURB_LACF3 ;  Q042G6, MURB_LACGA ;  A8YUF1, MURB_LACH4 ;
DR   Q74K66, MURB_LACJO ;  Q9CGD5, MURB_LACLA ;  A2RKV4, MURB_LACLM ;
DR   Q02Z11, MURB_LACLS ;  Q88YF4, MURB_LACPL ;  A5VIJ8, MURB_LACRD ;
DR   B2G632, MURB_LACRJ ;  Q1WSZ5, MURB_LACS1 ;  Q38VZ2, MURB_LACSS ;
DR   Q5X1S7, MURB_LEGPA ;  A5IAW3, MURB_LEGPC ;  Q5ZSA6, MURB_LEGPH ;
DR   Q5WTI8, MURB_LEGPL ;  Q6AH30, MURB_LEIXX ;  Q04VG7, MURB_LEPBJ ;
DR   Q04Y07, MURB_LEPBL ;  Q72MQ5, MURB_LEPIC ;  Q8EZC5, MURB_LEPIN ;
DR   Q03VW0, MURB_LEUMM ;  Q92BT5, MURB_LISIN ;  C1L2X6, MURB_LISMC ;
DR   Q71ZQ0, MURB_LISMF ;  B8DE89, MURB_LISMH ;  Q8Y776, MURB_LISMO ;
DR   A0AIM3, MURB_LISW6 ;  B9EAD2, MURB_MACCJ ;  Q2W0H1, MURB_MAGSA ;
DR   A0L5M9, MURB_MAGSM ;  Q65WM5, MURB_MANSM ;  Q0AMW9, MURB_MARMM ;
DR   Q11GS7, MURB_MESSB ;  B7KSC5, MURB_METC4 ;  Q604V9, MURB_METCA ;
DR   A9VWV7, MURB_METEP ;  B1ZGP6, MURB_METPB ;  Q2RK77, MURB_MOOTA ;
DR   A0QLK9, MURB_MYCA1 ;  P65461, MURB_MYCBO ;  A1KFV6, MURB_MYCBP ;
DR   C1AKG0, MURB_MYCBT ;  A4T318, MURB_MYCGI ;  B8ZT90, MURB_MYCLB ;
DR   Q9CB48, MURB_MYCLE ;  B2HQU8, MURB_MYCMM ;  Q73SU8, MURB_MYCPA ;
DR   A0QQZ3, MURB_MYCS2 ;  A3PU80, MURB_MYCSJ ;  A1UAM4, MURB_MYCSK ;
DR   Q1BEB0, MURB_MYCSS ;  A5TZL0, MURB_MYCTA ;  P65460, MURB_MYCTU ;
DR   A0PVY7, MURB_MYCUA ;  Q1D0T2, MURB_MYXXD ;  Q5F9J9, MURB_NEIG1 ;
DR   A9M3P3, MURB_NEIM0 ;  Q9JV28, MURB_NEIMA ;  Q9K016, MURB_NEIMB ;
DR   Q0AJE3, MURB_NITEC ;  Q82VS1, MURB_NITEU ;  Q1QNU0, MURB_NITHX ;
DR   Q2Y640, MURB_NITMU ;  Q3J791, MURB_NITOC ;  Q3STS5, MURB_NITWN ;
DR   Q5YP42, MURB_NOCFA ;  B2J718, MURB_NOSP7 ;  Q8YM74, MURB_NOSS1 ;
DR   Q2G993, MURB_NOVAD ;  Q8ESR4, MURB_OCEIH ;  A6WZQ8, MURB_OCHA4 ;
DR   A5CD21, MURB_ORITB ;  B3CSQ9, MURB_ORITI ;  A1BAL1, MURB_PARDP ;
DR   A7HVU9, MURB_PARL1 ;  Q6MAQ1, MURB_PARUW ;  P57952, MURB_PASMU ;
DR   Q03GV3, MURB_PEDPA ;  Q3A2G8, MURB_PELCD ;  A1AU59, MURB_PELPD ;
DR   A5D143, MURB_PELTS ;  Q4FPK7, MURB_PELUB ;  A9BJV3, MURB_PETMO ;
DR   B4RFG1, MURB_PHEZH ;  Q7MYE5, MURB_PHOLL ;  Q6LLV2, MURB_PHOPR ;
DR   A4SVJ6, MURB_POLSQ ;  B2RJV4, MURB_PORG3 ;  Q7MUY2, MURB_PORGI ;
DR   Q6A6J8, MURB_PROAC ;  A2C5M2, MURB_PROM3 ;  Q7VEJ2, MURB_PROMA ;
DR   Q7V9C4, MURB_PROMM ;  Q7V3P9, MURB_PROMP ;  Q46I41, MURB_PROMT ;
DR   Q48L51, MURB_PSE14 ;  Q15NN9, MURB_PSEA6 ;  Q9HZM7, MURB_PSEAE ;
DR   Q4KFT1, MURB_PSEF5 ;  Q3IJU8, MURB_PSEHT ;  Q3K8J6, MURB_PSEPF ;
DR   Q88LM5, MURB_PSEPK ;  Q87YF8, MURB_PSESM ;  Q4ZVY7, MURB_PSEU2 ;
DR   Q4FT57, MURB_PSYA2 ;  Q1QAQ4, MURB_PSYCK ;  A5WDI5, MURB_PSYWF ;
DR   Q8XWC4, MURB_RALSO ;  B3PTV8, MURB_RHIE6 ;  Q2K6C3, MURB_RHIEC ;
DR   Q1ME35, MURB_RHIL3 ;  Q98KB5, MURB_RHILO ;  B5ZWJ2, MURB_RHILW ;
DR   Q92NM1, MURB_RHIME ;  C3MEM7, MURB_RHISN ;  Q7UVF9, MURB_RHOBA ;
DR   Q2IYK4, MURB_RHOP2 ;  Q07PT0, MURB_RHOP5 ;  P61616, MURB_RHOPA ;
DR   Q211U0, MURB_RHOPB ;  Q133X3, MURB_RHOPS ;  B3QFM9, MURB_RHOPT ;
DR   Q2RVU6, MURB_RHORT ;  A3PHT1, MURB_RHOS1 ;  Q3J4L9, MURB_RHOS4 ;
DR   A4WQD8, MURB_RHOS5 ;  B9KNK2, MURB_RHOSK ;  A8GMP7, MURB_RICAH ;
DR   A8GW95, MURB_RICB8 ;  Q1RHX1, MURB_RICBR ;  A8EXZ7, MURB_RICCK ;
DR   Q92IT8, MURB_RICCN ;  Q4UKP0, MURB_RICFE ;  A8F109, MURB_RICM5 ;
DR   Q9ZDS7, MURB_RICPR ;  C4K125, MURB_RICPU ;  B0BWS1, MURB_RICRO ;
DR   A8GRC0, MURB_RICRS ;  Q68XC1, MURB_RICTY ;  Q163J3, MURB_ROSDO ;
DR   Q1ASA8, MURB_RUBXD ;  A4FQ15, MURB_SACEN ;  A8LZF8, MURB_SALAI ;
DR   Q57H81, MURB_SALCH ;  Q5PK78, MURB_SALPA ;  Q8Z316, MURB_SALTI ;
DR   P37417, MURB_SALTY ;  A9KW85, MURB_SHEB9 ;  Q8EK85, MURB_SHEON ;
DR   A0KRK7, MURB_SHESA ;  A8G1G4, MURB_SHESH ;  Q0HNV5, MURB_SHESM ;
DR   Q0I0C3, MURB_SHESR ;  Q31U21, MURB_SHIBS ;  Q32AE8, MURB_SHIDS ;
DR   Q83PC7, MURB_SHIFL ;  Q3YV08, MURB_SHISS ;  Q5LU58, MURB_SILPO ;
DR   Q1GIU8, MURB_SILST ;  A6UB83, MURB_SINMW ;  Q01NJ5, MURB_SOLUE ;
DR   Q1GRY1, MURB_SPHAL ;  A5VDC3, MURB_SPHWW ;  A7WZM9, MURB_STAA1 ;
DR   A6TZL7, MURB_STAA2 ;  Q2FIQ3, MURB_STAA3 ;  Q2G069, MURB_STAA8 ;
DR   A5IQU2, MURB_STAA9 ;  Q2YSJ1, MURB_STAAB ;  Q5HHT2, MURB_STAAC ;
DR   A6QF47, MURB_STAAE ;  P65462, MURB_STAAM ;  P65463, MURB_STAAN ;
DR   Q6GIQ3, MURB_STAAR ;  Q6GB92, MURB_STAAS ;  A8Z012, MURB_STAAT ;
DR   P61431, MURB_STAAU ;  P61432, MURB_STAAW ;  B9DJN5, MURB_STACT ;
DR   Q5HQZ1, MURB_STAEQ ;  Q8CPZ7, MURB_STAES ;  Q4L4G3, MURB_STAHJ ;
DR   Q49VT7, MURB_STAS1 ;  Q3K0Y5, MURB_STRA1 ;  P65464, MURB_STRA3 ;
DR   P65465, MURB_STRA5 ;  Q82DR4, MURB_STRAW ;  Q9L0L7, MURB_STRCO ;
DR   C0MA63, MURB_STRE4 ;  A8AWE3, MURB_STRGC ;  Q8DUF8, MURB_STRMU ;
DR   Q99ZS9, MURB_STRP1 ;  Q04JV9, MURB_STRP2 ;  P0DC48, MURB_STRP3 ;
DR   B5E5P6, MURB_STRP4 ;  Q5XCA5, MURB_STRP6 ;  C1C7Z0, MURB_STRP7 ;
DR   Q8P150, MURB_STRP8 ;  Q1JBV7, MURB_STRPB ;  Q1JLT8, MURB_STRPC ;
DR   Q1JGY8, MURB_STRPD ;  Q1J6Q7, MURB_STRPF ;  A2REL5, MURB_STRPG ;
DR   B1ICI9, MURB_STRPI ;  B8ZKN7, MURB_STRPJ ;  Q48TP5, MURB_STRPM ;
DR   P65466, MURB_STRPN ;  P0DC49, MURB_STRPQ ;  B2IQK6, MURB_STRPS ;
DR   B5XLF2, MURB_STRPZ ;  P65467, MURB_STRR6 ;  A4W0S3, MURB_STRS2 ;
DR   C0MEX9, MURB_STRS7 ;  A3CMQ6, MURB_STRSV ;  A4VUI1, MURB_STRSY ;
DR   Q5LYN3, MURB_STRT1 ;  Q5M396, MURB_STRT2 ;  Q03JH0, MURB_STRTD ;
DR   B9DRZ6, MURB_STRU0 ;  C1CEX8, MURB_STRZJ ;  C1CL98, MURB_STRZP ;
DR   C1CQW7, MURB_STRZT ;  Q2LR56, MURB_SYNAS ;  P95837, MURB_SYNE7 ;
DR   A0LNZ0, MURB_SYNFM ;  Q2JTH4, MURB_SYNJA ;  Q5MZH9, MURB_SYNP6 ;
DR   A5GHN8, MURB_SYNPW ;  Q7UA72, MURB_SYNPX ;  A5GPX0, MURB_SYNR3 ;
DR   Q0IE56, MURB_SYNS3 ;  Q3ANM5, MURB_SYNSC ;  Q0AY75, MURB_SYNWW ;
DR   P74529, MURB_SYNY3 ;  Q8DLV6, MURB_THEEB ;  Q47LH5, MURB_THEFY ;
DR   A8F4M2, MURB_THELT ;  A6LN73, MURB_THEM4 ;  Q9X239, MURB_THEMA ;
DR   A5ILF5, MURB_THEP1 ;  B1LAW8, MURB_THESQ ;  Q72JP7, MURB_THET2 ;
DR   Q5SJC8, MURB_THET8 ;  Q8R8Z6, MURB_THETN ;  Q3SMH1, MURB_THIDA ;
DR   Q73RJ5, MURB_TREDE ;  O83128, MURB_TREPA ;  Q83HA7, MURB_TROW8 ;
DR   Q83FK5, MURB_TROWT ;  A5F3P9, MURB_VIBC3 ;  Q9KV40, MURB_VIBCH ;
DR   Q5E225, MURB_VIBF1 ;  Q87KP5, MURB_VIBPA ;  Q8DD33, MURB_VIBVU ;
DR   Q7MGQ8, MURB_VIBVY ;  Q8D243, MURB_WIGBR ;  Q73HL4, MURB_WOLPM ;
DR   B3CPS8, MURB_WOLPP ;  Q5GRK8, MURB_WOLTR ;  C0R2M2, MURB_WOLWR ;
DR   Q8PLJ3, MURB_XANAC ;  Q3BUJ8, MURB_XANC5 ;  Q4UTX4, MURB_XANC8 ;
DR   B0RTS4, MURB_XANCB ;  Q8P9R1, MURB_XANCP ;  Q2P3M1, MURB_XANOM ;
DR   B2SLC0, MURB_XANOP ;  Q5H0N1, MURB_XANOR ;  B2I9T6, MURB_XYLF2 ;
DR   Q9PAE6, MURB_XYLFA ;  B0U5I2, MURB_XYLFM ;  Q87A76, MURB_XYLFT ;
DR   Q8ZAN4, MURB_YERPE ;  Q66FR3, MURB_YERPS ;  Q9RNM8, MURB_ZYMMO ;
//
ID   1.1.1.159
DE   7-alpha-hydroxysteroid dehydrogenase.
CA   3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + NAD(+) =
CA   3-alpha,12-alpha-dihydroxy-7-oxo-5-beta-cholanate + NADH.
CC   -!- Catalyzes the oxidation of the 7-alpha-hydroxy group of bile acids
CC       and alcohols both in their free and conjugated forms.
CC   -!- The Bacteroides fragilis and Clostridium enzymes can also utilize
CC       NADP(+).
PR   PROSITE; PDOC00060;
DR   P0AET9, HDHA_ECO57 ;  P0AET8, HDHA_ECOLI ;
//
ID   1.1.1.160
DE   Dihydrobunolol dehydrogenase.
AN   Bunolol reductase.
CA   (+-)-5-((tert-butylamino)-2'-hydroxypropoxy)-1,2,3,4-tetrahydro-1-
CA   naphthol + NADP(+) = (+-)-5-((tert-butylamino)-2'-hydroxypropoxy)-3,4-
CA   dihydro-1(2H)-naphthalenone + NADPH.
CC   -!- Also acts, more slowly, with NAD(+).
//
ID   1.1.1.161
DE   Cholestanetetraol 26-dehydrogenase.
AN   TEHC-NAD oxidoreductase.
CA   (25R)-5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NAD(+) =
CA   (25R)-3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al + NADH.
//
ID   1.1.1.162
DE   Erythrulose reductase.
AN   D-erythrulose reductase.
CA   D-threitol + NADP(+) = D-erythrulose + NADPH.
CC   -!- NAD(+) is also utilized, but more slowly.
PR   PROSITE; PDOC00060;
DR   Q8JIS3, DER_CHICK  ;
//
ID   1.1.1.163
DE   Cyclopentanol dehydrogenase.
CA   Cyclopentanol + NAD(+) = cyclopentanone + NADH.
CC   -!- 4-methylcyclohexanol and cyclohexanol can also act as substrates.
DR   Q8GAV9, CPNA_COMS9 ;  Q937L4, CPNA_COMTE ;
//
ID   1.1.1.164
DE   Hexadecanol dehydrogenase.
CA   Hexadecanol + NAD(+) = hexadecanal + NADH.
CC   -!- The liver enzyme acts on long-chain alcohols from C(8) to C(16).
CC   -!- The Euglena enzyme also oxidizes the corresponding aldehydes to fatty
CC       acids.
//
ID   1.1.1.165
DE   2-alkyn-1-ol dehydrogenase.
CA   2-butyne-1,4-diol + NAD(+) = 4-hydroxy-2-butynal + NADH.
CC   -!- Acts on a variety of 2-alkyn-1-ols, and also on 1,4-butanediol.
CC   -!- NADP(+) also acts as acceptor, but more slowly.
//
ID   1.1.1.166
DE   Hydroxycyclohexanecarboxylate dehydrogenase.
CA   (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD(+) = (1S,4S)-4-
CA   hydroxy-3-oxocyclohexane-1-carboxylate + NADH.
CC   -!- Acts on hydroxycyclohexanecarboxylates that have an equatorial
CC       carboxy group at C-1, an axial hydroxy group at C-3 and an equatorial
CC       hydroxy or carbonyl group at C-4, including (-)-quinate and (-)-
CC       shikimate.
//
ID   1.1.1.167
DE   Hydroxymalonate dehydrogenase.
CA   Hydroxymalonate + NAD(+) = oxomalonate + NADH.
//
ID   1.1.1.168
DE   2-dehydropantolactone reductase (A-specific).
AN   2-dehydropantoyl-lactone reductase (A-specific).
AN   2-ketopantoyl lactone reductase.
AN   Ketopantoyl lactone reductase.
CA   (R)-pantolactone + NADP(+) = 2-dehydropantolactone + NADPH.
CC   -!- The enzyme from Saccharomyces cerevisiae differs from that from
CC       Escherichia coli (EC 1.1.1.214), which is specific for the B-face of
CC       NADP, and in receptor requirements from EC 1.1.99.26.
//
ID   1.1.1.169
DE   2-dehydropantoate 2-reductase.
AN   Ketopantoate reductase.
AN   Ketopantoic acid reductase.
AN   KPA reductase.
CA   (R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH.
DR   O67619, PANE_AQUAE ;  O28578, PANE_ARCFU ;  O34661, PANE_BACSU ;
DR   Q9ABG6, PANE_CAUCR ;  Q8XE72, PANE_ECO57 ;  P0A9J4, PANE_ECOLI ;
DR   Q9HRF0, PANE_HALSA ;  Q9CFY8, PANE_LACLA ;  Q929X1, PANE_LISIN ;
DR   Q8Y5L2, PANE_LISMO ;  Q50648, PANE_MYCTU ;  Q8YX96, PANE_NOSS1 ;
DR   Q9HW09, PANE_PSEAE ;  Q9V0N0, PANE_PYRAB ;  Q8ZT70, PANE_PYRAE ;
DR   O50098, PANE_PYRHO ;  Q987N5, PANE_RHILO ;  Q8Z8W3, PANE_SALTI ;
DR   P37402, PANE_SALTY ;  Q9HDU6, PANE_SCHPO ;  P0A9J5, PANE_SHIFL ;
DR   P65666, PANE_STRP1 ;  P0DC92, PANE_STRP3 ;  Q5XCQ0, PANE_STRP6 ;
DR   Q8P1F1, PANE_STRP8 ;  P0DC93, PANE_STRPQ ;  Q9KPQ9, PANE_VIBCH ;
DR   P38787, PANE_YEAST ;  Q8ZC51, PANE_YERPE ;
//
ID   1.1.1.170
DE   Sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating).
AN   3-beta-hydroxy-4-alpha-methylcholestenecarboxylate 3-dehydrogenase
AN   (decarboxylating).
AN   3-beta-hydroxy-4-beta-methylcholestenecarboxylate 3-dehydrogenase
AN   (decarboxylating).
AN   3-beta-hydroxy-4-beta-methylcholestenoate dehydrogenase.
AN   Sterol 4-alpha-carboxylic decarboxylase.
CA   3-beta-hydroxy-4-beta-methyl-5-alpha-cholest-7-ene-4-alpha-carboxylate +
CA   NAD(P)(+) = 4-alpha-methyl-5-alpha-cholest-7-en-3-one + CO(2) + NAD(P)H.
CC   -!- Also acts on 3-beta-hydroxy-5-alpha-cholest-7-ene-4-alpha-
CC       carboxylate.
DR   O43050, ERG26_SCHPO;  P53199, ERG26_YEAST;  Q9FX01, HSDD1_ARATH;
DR   Q67ZE1, HSDD2_ARATH;  A9X4U2, HSDD3_ARATH;  Q3ZBE9, NSDHL_BOVIN;
DR   Q54L85, NSDHL_DICDI;  Q15738, NSDHL_HUMAN;  Q9R1J0, NSDHL_MOUSE;
DR   Q5PPL3, NSDHL_RAT  ;
//
ID   1.1.1.171
DE   Transferred entry: 1.5.1.20.
//
ID   1.1.1.172
DE   2-oxoadipate reductase.
AN   2-ketoadipate reductase.
AN   Alpha-ketoadipate reductase.
CA   2-hydroxyadipate + NAD(+) = 2-oxoadipate + NADH.
//
ID   1.1.1.173
DE   L-rhamnose 1-dehydrogenase.
CA   L-rhamnofuranose + NAD(+) = L-rhamno-1,4-lactone + NADH.
//
ID   1.1.1.174
DE   Cyclohexane-1,2-diol dehydrogenase.
CA   Trans-cyclohexane-1,2-diol + NAD(+) = 2-hydroxycyclohexan-1-one + NADH.
CC   -!- Also oxidizes, more slowly, the cis isomer and
CC       2-hydroxycyclohexanone.
//
ID   1.1.1.175
DE   D-xylose 1-dehydrogenase.
AN   D-xylose dehydrogenase.
AN   NAD-D-xylose dehydrogenase.
AN   NAD-linked D-xylose dehydrogenase.
CA   D-xylose + NAD(+) = D-xylonolactone + NADH.
PR   PROSITE; PDOC00061;
DR   Q6Y0Z3, XYL1_CANPA ;
//
ID   1.1.1.176
DE   12-alpha-hydroxysteroid dehydrogenase.
CA   3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + NADP(+) =
CA   3-alpha,7-alpha-dihydroxy-12-oxo-5-beta-cholanate + NADPH.
CC   -!- Catalyzes the oxidation of the 12-alpha-hydroxy group of bile acids,
CC       both in their free and conjugated form.
CC   -!- Also acts on bile alcohols.
DR   P21215, 12AH_CLOS4 ;
//
ID   1.1.1.177
DE   Glycerol-3-phosphate 1-dehydrogenase (NADP(+)).
AN   Glycerin-3-phosphate dehydrogenase.
CA   sn-glycerol 3-phosphate + NADP(+) = D-glyceraldehyde 3-phosphate + NADPH.
//
ID   1.1.1.178
DE   3-hydroxy-2-methylbutyryl-CoA dehydrogenase.
AN   2-methyl-3-hydroxybutyryl-CoA dehydrogenase.
CA   (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA + NAD(+) = 2-methylacetoacetyl-CoA
CA   + NADH.
CC   -!- Also acts, more slowly, on (2S,3S)-2-hydroxy-3-methylpentanoyl-CoA.
PR   PROSITE; PDOC00060;
DR   O02691, HCD2_BOVIN ;  O18404, HCD2_DROME ;  Q99714, HCD2_HUMAN ;
DR   O08756, HCD2_MOUSE ;  O70351, HCD2_RAT   ;
//
ID   1.1.1.179
DE   D-xylose 1-dehydrogenase (NADP(+)).
AN   D-xylose-NADP dehydrogenase.
CA   D-xylose + NADP(+) = D-xylono-1,5-lactone + NADPH.
CC   -!- Also acts, more slowly, on L-arabinose and D-ribose.
DR   Q148L6, DHDH_BOVIN ;  Q9TV68, DHDH_CANFA ;  Q642M9, DHDH_DANRE ;
DR   Q9UQ10, DHDH_HUMAN ;  Q9TQS6, DHDH_MACFA ;  Q7JK39, DHDH_MACFU ;
DR   Q9DBB8, DHDH_MOUSE ;  Q9TV69, DHDH_PIG   ;  Q5R5J5, DHDH_PONAB ;
DR   Q9TV70, DHDH_RABIT ;  Q6DKE0, DHDH_XENLA ;  Q6DF30, DHDH_XENTR ;
//
ID   1.1.1.180
DE   Transferred entry: 1.1.1.131.
//
ID   1.1.1.181
DE   Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase.
AN   3-beta-hydroxy-Delta(5)-C(27)-steroid oxidoreductase.
CA   Cholest-5-ene-3-beta,7-alpha-diol + NAD(+) = 7-alpha-hydroxycholest-4-
CA   en-3-one + NADH.
CC   -!- Highly specific for 3-beta-hydroxy-C(27)-steroids with Delta(5)-
CC       double bond.
DR   Q9H2F3, 3BHS7_HUMAN;  Q9EQC1, 3BHS7_MOUSE;  O35048, 3BHS7_RAT  ;
//
ID   1.1.1.182
DE   Transferred entry: 1.1.1.198, 1.1.1.227 and 1.1.1.228.
//
ID   1.1.1.183
DE   Geraniol dehydrogenase.
CA   Geraniol + NADP(+) = geranial + NADPH.
CC   -!- Also acts, more slowly, on nerol, farnesol and citronellol.
DR   Q2KNL6, GEDH1_OCIBA;
//
ID   1.1.1.184
DE   Carbonyl reductase (NADPH).
AN   Aldehyde reductase I.
AN   NADPH-dependent carbonyl reductase.
AN   Prostaglandin 9-ketoreductase.
AN   Xenobiotic ketone reductase.
CA   R-CHOH-R' + NADP(+) = R-CO-R' + NADPH.
CC   -!- Acts on a wide range of carbonyl compounds, including quinones,
CC       aromatic aldehydes, ketoaldehydes, daunorubicin, and prostaglandins
CC       E and F, reducing them to the corresponding alcohol.
CC   -!- B-specific with respect to NADPH (cf. EC 1.1.1.2).
PR   PROSITE; PDOC00060;
DR   Q3SZD7, CBR1_BOVIN ;  P16152, CBR1_HUMAN ;  Q8MI29, CBR1_MACFA ;
DR   P48758, CBR1_MOUSE ;  Q28960, CBR1_PIG   ;  Q5RCU5, CBR1_PONAB ;
DR   P47844, CBR1_RABIT ;  P47727, CBR1_RAT   ;  P08074, CBR2_MOUSE ;
DR   Q29529, CBR2_PIG   ;  O75828, CBR3_HUMAN ;  Q8SPU8, DHRS4_BOVIN;
DR   Q9BTZ2, DHRS4_HUMAN;  Q99LB2, DHRS4_MOUSE;  Q8WNV7, DHRS4_PIG  ;
DR   Q5RCF8, DHRS4_PONAB;  Q9GKX2, DHRS4_RABIT;  Q8VID1, DHRS4_RAT  ;
//
ID   1.1.1.185
DE   L-glycol dehydrogenase.
CA   An L-glycol + NAD(P)(+) = a 2-hydroxycarbonyl compound + NAD(P)H.
CC   -!- The 2-hydroxycarbonyl compound formed can be further oxidized to a
CC       vicinal dicarbonyl compound.
CC   -!- In the reverse direction, vicinal diketones, glyceraldehyde, glyoxal,
CC       methylglyoxal, 2-oxo-hydroxyketones and 2-ketoacid esters can be
CC       reduced.
//
ID   1.1.1.186
DE   dTDP-galactose 6-dehydrogenase.
AN   Thymidine-diphosphate-galactose dehydrogenase.
CA   dTDP-D-galactose + 2 NADP(+) + H(2)O = dTDP-D-galacturonate + 2 NADPH.
//
ID   1.1.1.187
DE   GDP-4-dehydro-D-rhamnose reductase.
AN   GDP-4-keto-6-deoxy-D-mannose reductase.
AN   GDP-4-keto-D-rhamnose reductase.
AN   Guanosine diphosphate-4-keto-D-rhamnose reductase.
CA   GDP-6-deoxy-D-mannose + NAD(P)(+) = GDP-4-dehydro-6-deoxy-D-mannose +
CA   NAD(P)H.
CC   -!- In the reverse reaction, a mixture of GDP-D-rhamnose and its C-4
CC       epimer is formed.
//
ID   1.1.1.188
DE   Prostaglandin-F synthase.
AN   PGD(2) 11-ketoreductase.
AN   PGF synthetase.
AN   Prostaglandin 11-ketoreductase.
AN   Prostaglandin-D(2) 11-ketoreductase.
AN   Prostaglandin-D(2) 11-reductase.
AN   Prostaglandin-D(2) ketoreductase.
AN   Prostaglandin-F synthetase.
CA   (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate +
CA   NADP(+) = (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate
CA   + NADPH.
CC   -!- Reduces prostaglandin D(2) and prostaglandin H(2) to prostaglandin
CC       F(2); prostaglandin D(2) is not an intermediate in the reduction of
CC       prostaglandin H(2).
CC   -!- Also catalyzes the reduction of a number of carbonyl compounds, such
CC       as 9,10-phenanthroquinone and 4-nitroacetophenone.
PR   PROSITE; PDOC00061;
DR   P42330, AK1C3_HUMAN;  Q5R7C9, AK1C3_PONAB;  P05980, PGFS1_BOVIN;
DR   P52897, PGFS2_BOVIN;
//
ID   1.1.1.189
DE   Prostaglandin-E(2) 9-reductase.
AN   9-keto-prostaglandin E(2) reductase.
AN   9-ketoprostaglandin reductase.
AN   PGE(2) 9-ketoreductase.
AN   PGE(2) 9-oxoreductase.
AN   Prostaglandin-E(2) 9-oxoreductase.
AN   Prostaglandin-E2 9-reductase.
CA   (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate +
CA   NADP(+) = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate
CA   + NADPH.
CC   -!- Reduces prostaglandin E(2) to prostaglandin F(2)-alpha.
CC   -!- A number of other 9-oxo- and 15-oxo-prostaglandin derivatives can
CC       also be reduced to the corresponding hydroxy compounds.
CC   -!- May be identical with EC 1.1.1.197.
PR   PROSITE; PDOC00060;
DR   Q3SZD7, CBR1_BOVIN ;  P16152, CBR1_HUMAN ;  Q8MI29, CBR1_MACFA ;
DR   P48758, CBR1_MOUSE ;  Q28960, CBR1_PIG   ;  Q5RCU5, CBR1_PONAB ;
DR   P47844, CBR1_RABIT ;  P47727, CBR1_RAT   ;  P80508, PE2R_RABIT ;
//
ID   1.1.1.190
DE   Indole-3-acetaldehyde reductase (NADH).
AN   Indoleacetaldehyde reductase.
CA   (Indol-3-yl)ethanol + NAD(+) = (indol-3-yl)acetaldehyde + NADH.
DR   O13848, I3ACR_SCHPO;
//
ID   1.1.1.191
DE   Indole-3-acetaldehyde reductase (NADPH).
CA   (Indol-3-yl)ethanol + NADP(+) = (indol-3-yl)acetaldehyde + NADPH.
DR   O13848, I3ACR_SCHPO;
//
ID   1.1.1.192
DE   Long-chain-alcohol dehydrogenase.
AN   Fatty alcohol oxidoreductase.
CA   A long-chain alcohol + 2 NAD(+) + H(2)O = a long-chain carboxylate +
CA   2 NADH.
CC   -!- Hexadecanol is a good substrate.
//
ID   1.1.1.193
DE   5-amino-6-(5-phosphoribosylamino)uracil reductase.
CA   5-amino-6-(5-phospho-D-ribitylamino)uracil + NADP(+) = 5-amino-6-
CA   (5-phospho-D-ribosylamino)uracil + NADPH.
DR   O28272, RIB7_ARCFU ;  Q757H6, RIB7_ASHGO ;  Q6FU96, RIB7_CANGA ;
DR   Q6BII9, RIB7_DEBHA ;  Q6CJ61, RIB7_KLULA ;  Q9P4B8, RIB7_KLUMA ;
DR   Q58085, RIB7_METJA ;  O26337, RIB7_METTH ;  Q9P7L3, RIB7_SCHPO ;
DR   P95872, RIB7_SULSO ;  P33312, RIB7_YEAST ;  P57534, RIBD2_BUCAI;
DR   Q8K9A3, RIBD2_BUCAP;  P50853, RIBD_ACTPL ;  O66534, RIBD_AQUAE ;
DR   P70814, RIBD_BACAM ;  P17618, RIBD_BACSU ;  Q89AB0, RIBD_BUCBP ;
DR   Q9PLJ6, RIBD_CHLMU ;  Q9Z735, RIBD_CHLPN ;  O84735, RIBD_CHLTR ;
DR   O24750, RIBD_CORAM ;  P25539, RIBD_ECOLI ;  P44326, RIBD_HAEIN ;
DR   P71677, RIBD_MYCTU ;  Q55158, RIBD_SYNY3 ;
//
ID   1.1.1.194
DE   Coniferyl-alcohol dehydrogenase.
CA   Coniferyl alcohol + NADP(+) = coniferyl aldehyde + NADPH.
CC   -!- Specific for coniferyl alcohol; does not act on cinnamyl alcohol,
CC       4-coumaryl alcohol or sinapyl alcohol.
//
ID   1.1.1.195
DE   Cinnamyl-alcohol dehydrogenase.
AN   CAD.
CA   Cinnamyl alcohol + NADP(+) = cinnamaldehyde + NADPH.
CC   -!- Acts on coniferyl alcohol, sinapyl alcohol, 4-coumaryl alcohol and
CC       cinnamyl alcohol (cf. EC 1.1.1.194).
PR   PROSITE; PDOC00058;
DR   Q6ERX1, CAD8A_ORYSJ;  Q6ERW9, CAD8B_ORYSJ;  Q6ERW7, CAD8C_ORYSJ;
DR   Q6ERW5, CAD8D_ORYSJ;  P42495, CADH1_ARACO;  Q9CAI3, CADH1_ARATH;
DR   Q42726, CADH1_EUCGU;  Q2KNL5, CADH1_OCIBA;  Q8H859, CADH1_ORYSJ;
DR   P85913, CADH1_PSEMZ;  P30359, CADH1_TOBAC;  Q9SJ25, CADH2_ARATH;
DR   P31655, CADH2_EUCGU;  Q6ZHS4, CADH2_ORYSJ;  O82035, CADH2_PICAB;
DR   P85916, CADH2_PSEMZ;  P30360, CADH2_TOBAC;  Q9SJ10, CADH3_ARATH;
DR   Q337Y2, CADH3_ORYSJ;  P48523, CADH4_ARATH;  Q2R114, CADH4_ORYSJ;
DR   O49482, CADH5_ARATH;  Q0J6T3, CADH5_ORYSJ;  O65621, CADH6_ARATH;
DR   Q7XWU3, CADH6_ORYSJ;  Q02971, CADH7_ARATH;  Q0JA75, CADH7_ORYSJ;
DR   Q08350, CADH7_PICAB;  Q02972, CADH8_ARATH;  P42734, CADH9_ARATH;
DR   Q10PS6, CADH9_ORYSJ;  P50746, CADH_EUCBO ;  O64969, CADH_EUCGL ;
DR   O22380, CADH_LOLPR ;  O24562, CADH_MAIZE ;  P31656, CADH_MEDSA ;
DR   Q40976, CADH_PINRA ;  P41637, CADH_PINTA ;  P31657, CADH_POPDE ;
DR   O82056, CADH_SACOF ;
//
ID   1.1.1.196
DE   15-hydroxyprostaglandin-D dehydrogenase (NADP(+)).
AN   Prostaglandin-D 15-dehydrogenase (NADP(+)).
AN   Prostaglandin-D 15-dehydrogenase (NADP+).
CA   (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate + NADP(+)
CA   = (5Z,13E)-9-alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate + NADPH.
CC   -!- Specific for prostaglandins D (cf. EC 1.1.1.141 and EC 1.1.1.197).
//
ID   1.1.1.197
DE   15-hydroxyprostaglandin dehydrogenase (NADP(+)).
CA   (13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NADP(+) = (13E)-
CA   11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADPH.
CC   -!- Acts on prostaglandins E(2), F(2)-alpha and B(1), but not on
CC       prostaglandin D(2) (cf. EC 1.1.1.141 and EC 1.1.1.196).
CC   -!- May be identical with EC 1.1.1.189.
PR   PROSITE; PDOC00060;
DR   Q3SZD7, CBR1_BOVIN ;  P16152, CBR1_HUMAN ;  Q8MI29, CBR1_MACFA ;
DR   P48758, CBR1_MOUSE ;  Q28960, CBR1_PIG   ;  Q5RCU5, CBR1_PONAB ;
DR   P47844, CBR1_RABIT ;  P47727, CBR1_RAT   ;
//
ID   1.1.1.198
DE   (+)-borneol dehydrogenase.
CA   (+)-borneol + NAD(+) = (+)-camphor + NADH.
CC   -!- NADP(+) can also act, more slowly.
CC   -!- Formerly EC 1.1.1.182.
//
ID   1.1.1.199
DE   (S)-usnate reductase.
CA   (6R)-2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-
CA   methyl-2,4-cyclohexadien-1-one + NAD(+) = (S)-usnate + NADH.
//
ID   1.1.1.200
DE   Aldose-6-phosphate reductase (NADPH).
AN   NADP-dependent D-sorbitol-6-phosphate dehydrogenase.
CA   D-sorbitol 6-phosphate + NADP(+) = D-glucose 6-phosphate + NADPH.
CC   -!- In the reverse reaction, acts also on D-galactose 6-phosphate and,
CC       more slowly, on D-mannose 6-phosphate and 2-deoxy-D-glucose
CC       6-phosphate.
PR   PROSITE; PDOC00061;
DR   P28475, S6PD_MALDO ;
//
ID   1.1.1.201
DE   7-beta-hydroxysteroid dehydrogenase (NADP(+)).
AN   NADP-dependent 7-beta-hydroxysteroid dehydrogenase.
CA   A 7-beta-hydroxysteroid + NADP(+) = a 7-oxosteroid + NADPH.
CC   -!- Catalyzes the oxidation of the 7-beta-hydroxy group of bile acids
CC       such as ursodeoxycholate.
//
ID   1.1.1.202
DE   1,3-propanediol dehydrogenase.
AN   1,3-propanediol oxidoreductase.
AN   3-hydroxypropionaldehyde reductase.
CA   Propane-1,3-diol + NAD(+) = 3-hydroxypropanal + NADH.
PR   PROSITE; PDOC00059;
DR   P45513, DHAT_CITFR ;  Q59477, DHAT_KLEPN ;
//
ID   1.1.1.203
DE   Uronate dehydrogenase.
AN   Uronic acid dehydrogenase.
CA   D-galacturonate + NAD(+) + H(2)O = D-galactarate + NADH.
CC   -!- Also acts on D-glucuronate.
CC   -!- Formerly EC 1.2.1.35.
//
ID   1.1.1.204
DE   Transferred entry: 1.17.1.4.
//
ID   1.1.1.205
DE   IMP dehydrogenase.
AN   IMP oxidoreductase.
AN   Inosinate dehydrogenase.
AN   Inosine 5'-monophosphate dehydrogenase.
AN   Inosine monophosphate oxidoreductase.
AN   Inosinic acid dehydrogenase.
CA   Inosine 5'-phosphate + NAD(+) + H(2)O = xanthosine 5'-phosphate + NADH.
CC   -!- The enzyme acts on the hydroxy group of the hydrated derivative of
CC       the substrate.
CC   -!- Formerly EC 1.2.1.14.
PR   PROSITE; PDOC00391;
DR   P47996, IMDH1_ARATH;  P20839, IMDH1_HUMAN;  P50096, IMDH1_MOUSE;
DR   P39567, IMDH1_YEAST;  Q9SA34, IMDH2_ARATH;  Q3SWY3, IMDH2_BOVIN;
DR   P12269, IMDH2_CRIGR;  P12268, IMDH2_HUMAN;  P24547, IMDH2_MOUSE;
DR   P38697, IMDH2_YEAST;  O00086, IMDH3_CANAL;  P50095, IMDH3_YEAST;
DR   P50094, IMDH4_YEAST;  P31002, IMDH_ACICA ;  O67820, IMDH_AQUAE ;
DR   Q9KGN8, IMDH_BACHD ;  P21879, IMDH_BACSU ;  P49058, IMDH_BORBU ;
DR   O50316, IMDH_CHLP8 ;  Q8KCW4, IMDH_CHLTE ;  Q54QQ0, IMDH_DICDI ;
DR   Q07152, IMDH_DROME ;  P0ADG8, IMDH_ECO57 ;  P0ADG7, IMDH_ECOLI ;
DR   P44334, IMDH_HAEIN ;  Q9ZL14, IMDH_HELPJ ;  P56088, IMDH_HELPY ;
DR   P21620, IMDH_LEIDO ;  Q59011, IMDH_METJA ;  P65168, IMDH_MYCBO ;
DR   Q49729, IMDH_MYCLE ;  P65167, IMDH_MYCTU ;  Q9L6B7, IMDH_PASMU ;
DR   Q12658, IMDH_PNECA ;  Q9UY49, IMDH_PYRAB ;  P42851, IMDH_PYRFU ;
DR   O58045, IMDH_PYRHO ;  Q9KH33, IMDH_RHITR ;  O14344, IMDH_SCHPO ;
DR   P0ADG9, IMDH_SHIFL ;  Q2FJM6, IMDH_STAA3 ;  Q2G0Y7, IMDH_STAA8 ;
DR   Q2YVL6, IMDH_STAAB ;  Q5HIQ7, IMDH_STAAC ;  P65169, IMDH_STAAM ;
DR   P99106, IMDH_STAAN ;  Q6GJQ7, IMDH_STAAR ;  Q6GC82, IMDH_STAAS ;
DR   Q8NY70, IMDH_STAAW ;  Q5HRX2, IMDH_STAEQ ;  Q8CMQ7, IMDH_STAES ;
DR   Q4L385, IMDH_STAHJ ;  Q49UU8, IMDH_STAS1 ;  P0C0H7, IMDH_STRP1 ;
DR   P0DB88, IMDH_STRP3 ;  Q5X9A3, IMDH_STRP6 ;  P68839, IMDH_STRP8 ;
DR   P0DB89, IMDH_STRPQ ;  P0C0H6, IMDH_STRPY ;  P50097, IMDH_TRIFO ;
DR   P50098, IMDH_TRYBB ;
//
ID   1.1.1.206
DE   Tropinone reductase I.
AN   TR-I.
AN   Tropine dehydrogenase.
AN   Tropinone reductase.
CA   Tropine + NADP(+) = tropinone + NADPH.
CC   -!- Also oxidizes other tropan-3-alpha-ols, but not the corresponding
CC       beta-derivatives.
CC   -!- Represents, along with EC 1.1.1.236, a branch point in tropane
CC       alkaloid metabolism.
CC   -!- Tropine (the product of EC 1.1.1.206) is incorporated into
CC       hyoscyamine and scopolamine whereas pseudotropine (the product of
CC       EC 1.1.1.236) is the first specific metabolite on the pathway to the
CC       calystegines.
CC   -!- Both enzymes are always found together in any given tropane-alkaloid-
CC       producing species, have a common substrate, tropinone, and are
CC       strictly stereospecific.
PR   PROSITE; PDOC00060;
DR   P50162, TRN1_DATST ;
//
ID   1.1.1.207
DE   (-)-menthol dehydrogenase.
AN   Monoterpenoid dehydrogenase.
CA   (-)-menthol + NADP(+) = (-)-menthone + NADPH.
CC   -!- Acts on a number of other cyclohexanols and cyclohexenols.
CC   -!- Not identical with EC 1.1.1.208.
//
ID   1.1.1.208
DE   (+)-neomenthol dehydrogenase.
AN   Monoterpenoid dehydrogenase.
CA   (+)-neomenthol + NADP(+) = (-)-menthone + NADPH.
CC   -!- Acts on a number of other cyclohexanols and cyclohexenols.
CC   -!- Not identical with EC 1.1.1.207.
DR   B2X050, MNR1_CAPAN ;  Q9M2E2, SDR1_ARATH ;
//
ID   1.1.1.209
DE   3(or 17)-alpha-hydroxysteroid dehydrogenase.
CA   Androsterone + NAD(P)(+) = 5-alpha-androstane-3,17-dione + NAD(P)H.
CC   -!- Acts on the 3-alpha-hydroxy group of androgens of the 5-alpha-
CC       androstane series; and also, more slowly, on the 17-alpha-hydroxyl
CC       group of both androgenic and estrogenic substrates (cf. EC 1.1.1.51).
//
ID   1.1.1.210
DE   3-beta-(or 20-alpha)-hydroxysteroid dehydrogenase.
AN   3-beta-HSD.
AN   Progesterone reductase.
CA   5-alpha-androstan-3-beta,17-beta-diol + NADP(+) = 17-beta-hydroxy-5-
CA   alpha-androstan-3-one + NADPH.
CC   -!- Also acts on 20-alpha-hydroxysteroids.
//
ID   1.1.1.211
DE   Long-chain-3-hydroxyacyl-CoA dehydrogenase.
AN   Beta-hydroxyacyl-CoA dehydrogenase.
CA   (S)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + NADH.
CC   -!- Acts most rapidly on derivatives with chain length C(8) or C(10) (cf.
CC       EC 1.1.1.35).
DR   P40939, ECHA_HUMAN ;  Q8BMS1, ECHA_MOUSE ;  Q29554, ECHA_PIG   ;
DR   Q64428, ECHA_RAT   ;
//
ID   1.1.1.212
DE   3-oxoacyl-[acyl-carrier-protein] reductase (NADH).
CA   (3R)-3-hydroxyacyl-[acyl-carrier-protein] + NAD(+) = 3-oxoacyl-[acyl-
CA   carrier-protein] + NADH.
CC   -!- Forms part of the fatty acid synthase system in plants.
CC   -!- Can be separated from EC 1.1.1.100.
//
ID   1.1.1.213
DE   3-alpha-hydroxysteroid dehydrogenase (A-specific).
CA   Androsterone + NAD(P)(+) = 5-alpha-androstane-3,17-dione + NAD(P)H.
CC   -!- Also acts on other 3-alpha-hydroxysteroids.
CC   -!- A-specific with respect to NAD(+) or NADP(+) (cf. EC 1.1.1.50).
DR   P52895, AK1C2_HUMAN;  P42330, AK1C3_HUMAN;  Q5R7C9, AK1C3_PONAB;
DR   P23457, DIDH_RAT   ;
//
ID   1.1.1.214
DE   2-dehydropantolactone reductase (B-specific).
AN   2-dehydropantoyl-lactone reductase (B-specific).
AN   2-ketopantoyl lactone reductase.
AN   Ketopantoyl lactone reductase.
CA   (R)-pantolactone + NADP(+) = 2-dehydropantolactone + NADPH.
CC   -!- The Escherichia coli enzyme differs from that from Saccharomyces
CC       cerevisiae (EC 1.1.1.168), which is specific for the A-face of NADP,
CC       and in receptor requirements from EC 1.1.99.26.
//
ID   1.1.1.215
DE   Gluconate 2-dehydrogenase.
AN   2-keto-D-gluconate reductase.
AN   2-ketogluconate reductase.
CA   D-gluconate + NADP(+) = 2-dehydro-D-gluconate + NADPH.
CC   -!- Also acts on L-idonate, D-galactonate and D-xylonate.
DR   P37666, GHRB_ECOLI ;  O32264, TKRA_BACSU ;  Q54DP1, TKRA_DICDI ;
//
ID   1.1.1.216
DE   Farnesol dehydrogenase.
CA   2-trans,6-trans-farnesol + NADP(+) = 2-trans,6-trans-farnesal + NADPH.
CC   -!- Also acts, more slowly, on 2-cis,6-trans-farnesol, geraniol,
CC       citronerol and nerol.
//
ID   1.1.1.217
DE   Benzyl-2-methyl-hydroxybutyrate dehydrogenase.
AN   Benzyl 2-methyl-3-hydroxybutyrate dehydrogenase.
CA   Benzyl (2R,3S)-2-methyl-3-hydroxybutanoate + NADP(+) = benzyl 2-methyl-3-
CA   oxobutanoate + NADPH.
CC   -!- Also acts on benzyl (2S,3S)-2-methyl-3-hydroxybutanoate; otherwise
CC       highly specific.
//
ID   1.1.1.218
DE   Morphine 6-dehydrogenase.
AN   Naloxone reductase.
CA   Morphine + NAD(P)(+) = morphinone + NAD(P)H.
CC   -!- Also acts on some other alkaloids, including codeine, normorphine and
CC       ethylmorphine, but only very slowly on 7,8-saturated derivatives such
CC       as dihydromorphine and dihydrocodeine.
CC   -!- In the reverse direction, also reduces naloxone to the 6-alpha-
CC       hydroxy analog.
CC   -!- Activated by 2-mercaptoethanol.
PR   PROSITE; PDOC00061;
DR   P82809, AK1CD_MESAU;  Q02198, MORA_PSEPU ;  P82810, MORA_RABIT ;
//
ID   1.1.1.219
DE   Dihydrokaempferol 4-reductase.
AN   Dihydroflavanol 4-reductase.
AN   Dihydroflavonol 4-reductase.
AN   NADPH-dihydromyricetin reductase.
CA   Cis-3,4-leucopelargonidin + NADP(+) = (+)-dihydrokaempferol + NADPH.
CC   -!- Also acts, in the reverse direction, on (+)-dihydroquercetin and (+)-
CC       dihydromyricetin; each dihydroflavonol is reduced to the
CC       corresponding cis-flavan-3,4-diol.
CC   -!- NAD(+) can act instead of NADP(+), but more slowly.
CC   -!- Involved in the biosynthesis of anthocyanidins in plants.
DR   P14721, DFRA_ANTMA ;  P51102, DFRA_ARATH ;  P51103, DFRA_CALCH ;
DR   P51104, DFRA_DIACA ;  P51105, DFRA_GERHY ;  P51106, DFRA_HORVU ;
DR   P51108, DFRA_MAIZE ;  Q9XES5, DFRA_MALDO ;  P51109, DFRA_MEDSA ;
DR   P14720, DFRA_PETHY ;  Q84KP0, DFRA_PYRCO ;  P51107, DFRA_SOLLC ;
DR   P73212, DFRA_SYNY3 ;  P51110, DFRA_VITVI ;
//
ID   1.1.1.220
DE   6-pyruvoyltetrahydropterin 2'-reductase.
AN   6-pyruvoyl tetrahydropterin (2'-oxo)reductase.
AN   6-pyruvoyl-tetrahydropterin 2'-reductase.
AN   6PPH4(2'-oxo) reductase.
AN   Pyruvoyl-tetrahydropterin reductase.
CA   6-lactoyl-5,6,7,8-tetrahydropterin + NADP(+) = 6-pyruvoyltetrahydropterin
CA   + NADPH.
CC   -!- Not identical with EC 1.1.1.153.
//
ID   1.1.1.221
DE   Vomifoliol dehydrogenase.
AN   Vomifoliol 4'-dehydrogenase.
CA   (6S,9R)-6-hydroxy-3-oxo-alpha-ionol + NAD(+) = (6R)-6-hydroxy-3-oxo-
CA   alpha-ionone + NADH.
CC   -!- Oxidizes vomifoliol to dehydrovomifoliol; involved in the metabolism
CC       of abscisic acid in Corynebacterium sp.
//
ID   1.1.1.222
DE   (R)-4-hydroxyphenyllactate dehydrogenase.
AN   (R)-aromatic lactate dehydrogenase.
CA   (R)-3-(4-hydroxyphenyl)lactate + NAD(P)(+) = 3-(4-hydroxyphenyl)pyruvate
CA   + NAD(P)H.
CC   -!- Also acts, more slowly, on (R)-3-phenyllactate, (R)-3-(indol-3-
CC       yl)lactate and (R)-lactate.
//
ID   1.1.1.223
DE   Isopiperitenol dehydrogenase.
CA   (-)-trans-isopiperitenol + NAD(+) = (-)-isopiperitenone + NADH.
CC   -!- Acts on (-)-trans-isopiperitenol, (+)-trans-piperitenol and (+)-
CC       trans-pulegol.
CC   -!- Involved in the biosynthesis of menthol and related monoterpenes in
CC       peppermint (Mentha piperita) leaves.
//
ID   1.1.1.224
DE   Mannose-6-phosphate 6-reductase.
AN   NADPH-dependent M6P reductase.
AN   NADPH-mannose-6-P reductase.
CA   D-mannitol 1-phosphate + NADP(+) = D-mannose 6-phosphate + NADPH.
CC   -!- Involved in the biosynthesis of mannitol in celery (Apium graveolens)
CC       leaves.
//
ID   1.1.1.225
DE   Chlordecone reductase.
AN   CDR.
CA   Chlordecone alcohol + NADP(+) = chlordecone + NADPH.
CC   -!- Chlordecone, an organochlorine pesticide, is 1,1a,3,3a,4,5,5a,5b,6-
CC       decachlorooctahydro-1,3,4-metheno-2H-cyclobuta[cd]pentalen-2-one.
PR   PROSITE; PDOC00061;
DR   P17516, AK1C4_HUMAN;  Q95JH5, AK1C4_MACFA;  Q95JH4, AK1C4_MACFU;
//
ID   1.1.1.226
DE   4-hydroxycyclohexanecarboxylate dehydrogenase.
CA   Trans-4-hydroxycyclohexanecarboxylate + NAD(+) =
CA   4-oxocyclohexanecarboxylate + NADH.
CC   -!- The enzyme from Corynebacterium cyclohexanicum is highly specific for
CC       the trans-4-hydroxy derivative.
//
ID   1.1.1.227
DE   (-)-borneol dehydrogenase.
CA   (-)-borneol + NAD(+) = (-)-camphor + NADH.
CC   -!- NADP(+) can also act, more slowly.
CC   -!- Formerly EC 1.1.1.182.
//
ID   1.1.1.228
DE   (+)-sabinol dehydrogenase.
CA   (+)-cis-sabinol + NAD(+) = (+)-sabinone + NADH.
CC   -!- NADP(+) can also act, more slowly.
CC   -!- Involved in the biosynthesis of (+)-3-thujone and (-)-3-isothujone.
CC   -!- Formerly EC 1.1.1.182.
//
ID   1.1.1.229
DE   Diethyl 2-methyl-3-oxosuccinate reductase.
CA   Diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP(+) = diethyl 2-methyl-
CA   3-oxosuccinate + NADPH.
CC   -!- Also acts on diethyl (2S,3R)-2-methyl-3-hydroxysuccinate; and on the
CC       corresponding dimethyl esters.
//
ID   1.1.1.230
DE   3-alpha-hydroxyglycyrrhetinate dehydrogenase.
CA   3-alpha-hydroxyglycyrrhetinate + NADP(+) = 3-oxoglycyrrhetinate + NADPH.
CC   -!- Highly specific to 3-alpha-hydroxy derivatives of glycyrrhetinate and
CC       its analogs.
CC   -!- Not identical to EC 1.1.1.50.
//
ID   1.1.1.231
DE   15-hydroxyprostaglandin-I dehydrogenase (NADP(+)).
AN   PG I2 dehydrogenase.
AN   Prostacyclin dehydrogenase.
CA   (5Z,13E)-(15S)-6,9-alpha-epoxy-11-alpha,15-dihydroxyprosta-5,13-dienoate
CA   + NADP(+) = (5Z,13E)-6,9-alpha-epoxy-11-alpha-hydroxy-15-oxoprosta-5,13-
CA   dienoate + NADPH.
CC   -!- Specific for prostaglandin I(2).
//
ID   1.1.1.232
DE   15-hydroxyicosatetraenoate dehydrogenase.
CA   (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate + NAD(P)(+) =
CA   15-oxo-5,8,11-cis-13-trans-icosatetraenoate + NAD(P)H.
//
ID   1.1.1.233
DE   N-acylmannosamine 1-dehydrogenase.
AN   N-acetyl-D-mannosamine dehydrogenase.
AN   N-acyl-D-mannosamine dehydrogenase.
AN   N-acylmannosamine dehydrogenase.
CA   N-acyl-D-mannosamine + NAD(+) = N-acyl-D-mannosaminolactone + NADH.
CC   -!- Acts on acetyl-D-mannosamine and glycolyl-D-mannosamine.
CC   -!- Highly specific.
PR   PROSITE; PDOC00060;
DR   P22441, DHMA_FLAS1 ;
//
ID   1.1.1.234
DE   Flavanone 4-reductase.
CA   (2S)-flavan-4-ol + NADP(+) = (2S)-flavanone + NADPH.
CC   -!- Involved in the biosynthesis of 3-deoxyanthocyanidins from flavanones
CC       such as naringenin or eriodictyol.
DR   Q9XES5, DFRA_MALDO ;  Q84KP0, DFRA_PYRCO ;
//
ID   1.1.1.235
DE   8-oxocoformycin reductase.
CA   Coformycin + NADP(+) = 8-oxocoformycin + NADPH.
CC   -!- B-specific with respect to NADPH.
CC   -!- Also reduces 8-oxodeoxy-coformycin to the nucleoside antibiotic
CC       deoxycoformycin.
//
ID   1.1.1.236
DE   Tropinone reductase II.
AN   Pseudotropine forming tropinone reductase.
AN   TR-II.
AN   Tropinone reductase.
CA   Pseudotropine + NADP(+) = tropinone + NADPH.
CC   -!- Represents, along with EC 1.1.1.206, a branch point in tropane
CC       alkaloid metabolism.
CC   -!- Tropine (the product of EC 1.1.1.206) is incorporated into
CC       hyoscyamine and scopolamine whereas pseudotropine (the product of
CC       EC 1.1.1.236) is the first specific metabolite on the pathway to the
CC       calystegines.
CC   -!- Both enzymes are always found together in any given tropane-alkaloid-
CC       producing species, have a common substrate, tropinone, and are
CC       strictly stereospecific.
PR   PROSITE; PDOC00060;
DR   P50163, TRN2_DATST ;  P50164, TRN2_HYONI ;
//
ID   1.1.1.237
DE   Hydroxyphenylpyruvate reductase.
CA   3-(4-hydroxyphenyl)lactate + NAD(+) = 3-(4-hydroxyphenyl)pyruvate + NADH.
CC   -!- Also acts on 3-(3,4-dihydroxyphenyl)lactate.
CC   -!- Involved with EC 2.3.1.140 in the biosynthesis of rosmarinic acid.
//
ID   1.1.1.238
DE   12-beta-hydroxysteroid dehydrogenase.
CA   3-alpha,7-alpha,12-beta-trihydroxy-5-beta-cholanate + NADP(+) =
CA   3-alpha,7-alpha-dihydroxy-12-oxo-5-beta-cholanate + NADPH.
CC   -!- Acts on a number of bile acids, both in their free and conjugated
CC       forms.
//
ID   1.1.1.239
DE   3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)).
CA   Testosterone + NAD(+) = androst-4-ene-3,17-dione + NADH.
CC   -!- Also acts on other 17-beta-hydroxysteroids, on the 3-alpha-hydroxy
CC       group of pregnanes and bile acids, and on benzene dihydrodiol.
CC   -!- Different from EC 1.1.1.50 or EC 1.1.1.213.
//
ID   1.1.1.240
DE   N-acetylhexosamine 1-dehydrogenase.
CA   N-acetyl-D-glucosamine + H(2)O + NAD(+) = N-acetyl-D-glucosaminate +
CA   NADH.
CC   -!- Also acts on N-acetylgalactosamine and, more slowly,
CC       on N-acetylmannosamine.
//
ID   1.1.1.241
DE   6-endo-hydroxycineole dehydrogenase.
CA   6-endo-hydroxycineole + NAD(+) = 6-oxocineole + NADH.
//
ID   1.1.1.242
DE   Transferred entry: 1.3.1.69.
//
ID   1.1.1.243
DE   Carveol dehydrogenase.
CA   (-)-trans-carveol + NADP(+) = (-)-carvone + NADPH.
DR   O85057, LIHY_GEOSE ;
//
ID   1.1.1.244
DE   Methanol dehydrogenase.
CA   Methanol + NAD(+) = formaldehyde + NADH.
PR   PROSITE; PDOC00059;
DR   P31005, MEDH_BACMT ;
//
ID   1.1.1.245
DE   Cyclohexanol dehydrogenase.
CA   Cyclohexanol + NAD(+) = cyclohexanone + NADH.
CC   -!- Also oxidizes some other alicyclic alcohols and diols.
//
ID   1.1.1.246
DE   Pterocarpin synthase.
CA   Medicarpin + NADP(+) + H(2)O = vestitone + NADPH.
CC   -!- Catalyzes the final step in the biosynthesis of the pterocarpin
CC       phytoalexins medicarpin and maackiain.
//
ID   1.1.1.247
DE   Codeinone reductase (NADPH).
CA   Codeine + NADP(+) = codeinone + NADPH.
CC   -!- Catalyzes the reversible reduction of codeinone to codeine, which is
CC       a direct precursor of morphine in the opium poppy plant, Papaver
CC       somniferum.
//
ID   1.1.1.248
DE   Salutaridine reductase (NADPH).
CA   Salutaridinol + NADP(+) = salutaridine + NADPH.
CC   -!- Catalyzes the reversible reduction of salutaridine to salutaridinol,
CC       which is a direct precursor of morphinan alkaloids in the poppy
CC       plant.
DR   A4UHT7, SALR_PAPBR ;
//
ID   1.1.1.249
DE   Transferred entry: 2.5.1.46.
//
ID   1.1.1.250
DE   D-arabinitol 2-dehydrogenase.
AN   D-arabinitol 2-dehydrogenase (ribulose-forming).
CA   D-arabinitol + NAD(+) = D-ribulose + NADH.
PR   PROSITE; PDOC00060;
DR   P43066, ARDH_CANAL ;  P50166, ARDH_CANTR ;  P50167, ARDH_PICST ;
//
ID   1.1.1.251
DE   Galactitol-1-phosphate 5-dehydrogenase.
CA   Galactitol-1-phosphate + NAD(+) = L-tagatose 6-phosphate + NADH.
CF   Zinc.
PR   PROSITE; PDOC00058;
DR   P0A9S4, GATD_ECO57 ;  P0A9S3, GATD_ECOLI ;
//
ID   1.1.1.252
DE   Tetrahydroxynaphthalene reductase.
AN   T4HN reductase.
CA   Scytalone + NADP(+) = 1,3,6,8-tetrahydroxynaphthalene + NADPH.
CC   -!- Reduces 1,3,6,8-tetrahydroxynaphthalene to scytalone and also reduces
CC       1,3,8-trihydroxynaphthalene to vermelone.
CC   -!- Involved with EC 4.2.1.94 in the biosynthesis of melanin in
CC       pathogenic fungi.
CC   -!- Formerly EC 1.3.1.50.
PR   PROSITE; PDOC00060;
DR   Q12634, T4HR_MAGO7 ;
//
ID   1.1.1.253
DE   Transferred entry: 1.5.1.33.
//
ID   1.1.1.254
DE   (S)-carnitine 3-dehydrogenase.
AN   D-carnitine dehydrogenase.
CA   (S)-carnitine + NAD(+) = 3-dehydrocarnitine + NADH.
CC   -!- Specific for the (S)-enantiomer of carnitine, i.e., the enantiomer of
CC       the substrate of EC 1.1.1.108.
//
ID   1.1.1.255
DE   Mannitol dehydrogenase.
AN   MTD.
AN   NAD-dependent mannitol dehydrogenase.
CA   D-mannitol + NAD(+) = D-mannose + NADH.
CC   -!- The enzyme from Apium graveolens (celery) oxidizes alditols with a
CC       minimum requirement of 2R chirality at the carbon adjacent to the
CC       primary carbon undergoing the oxidation.
CC   -!- The enzyme is specific for NAD(+) and does not use NADP(+).
DR   Q43137, MTDH1_STYHU;  Q43138, MTDH3_STYHU;  Q38707, MTDH_APIGR ;
DR   Q9ZRF1, MTDH_FRAAN ;  O82515, MTDH_MEDSA ;  P93257, MTDH_MESCR ;
DR   P42754, MTDH_PETCR ;
//
ID   1.1.1.256
DE   Fluoren-9-ol dehydrogenase.
CA   Fluoren-9-ol + NAD(P)(+) = fluoren-9-one + NAD(P)H.
CC   -!- Involved in the pathway for fluorene metabolism in Arthrobacter sp.
//
ID   1.1.1.257
DE   4-(hydroxymethyl)benzenesulfonate dehydrogenase.
CA   4-(hydroxymethyl)benzenesulfonate + NAD(+) = 4-formylbenzenesulfonate +
CA   NADH.
CC   -!- Involved in the toluene-4-sulfonate degradation pathway in Comamonas
CC       testosteroni.
//
ID   1.1.1.258
DE   6-hydroxyhexanoate dehydrogenase.
CA   6-hydroxyhexanoate + NAD(+) = 6-oxohexanoate + NADH.
CC   -!- Involved in the cyclohexanol degradation pathway in Acinetobacter
CC       NCIB 9871.
//
ID   1.1.1.259
DE   3-hydroxypimeloyl-CoA dehydrogenase.
CA   3-hydroxypimeloyl-CoA + NAD(+) = 3-oxopimeloyl-CoA + NADH.
CC   -!- Involved in the anaerobic pathway of benzoate degradation in
CC       bacteria.
//
ID   1.1.1.260
DE   Sulcatone reductase.
CA   Sulcatol + NAD(+) = sulcatone + NADH.
CC   -!- Studies on the effects of growth-stage and nutrient supply on the
CC       stereochemistry of sulcatone reduction in Clostridia pasteurianum,
CC       C.tyrobutyricum and Lactobacillus brevis suggest that there may be at
CC       least two sulcatone reductases with different stereospecificities.
//
ID   1.1.1.261
DE   sn-glycerol-1-phosphate dehydrogenase.
AN   Glycerol-1-phosphate dehydrogenase (NAD(P)(+)).
AN   Gro1PDH.
CA   sn-glycerol-1-phosphate + NAD(P)(+) = glycerone phosphate + NAD(P)H.
CF   Zinc or nickel.
CC   -!- Responsible for the formation of archaea-specific sn-glycerol-1-
CC       phosphate, the first step in the biosynthesis of polar lipids in
CC       archaea.
CC   -!- It is the enantiomer of sn-glycerol 3-phosphate, the form of
CC       glycerophosphate found in bacteria and eukaryotes.
CC   -!- The other enzymes involved in the biosynthesis of polar lipids in
CC       archaea are EC 2.5.1.41 and EC 2.5.1.42, which together alkylate the
CC       hydroxy groups of glycerol 1-phosphate to give unsaturated
CC       archaetidic acid, which is acted upon by EC 2.7.7.67 to form CDP-
CC       unsaturated archaeol.
CC   -!- The final step in the pathway involves the addition of L-serine, with
CC       concomitant removal of CMP, leading to the production of unsaturated
CC       archaetidylserine.
CC   -!- Activity of the enzyme is stimulated by K(+).
DR   Q9YER2, G1PDH_AERPE;  O28599, G1PDH_ARCFU;  A7Z7G4, G1PDH_BACA2;
DR   Q9KBR3, G1PDH_BACHD;  Q65GC3, G1PDH_BACLD;  Q5WL08, G1PDH_BACSK;
DR   P94527, G1PDH_BACSU;  A8MC03, G1PDH_CALMQ;  A0RXV2, G1PDH_CENSY;
DR   B3EYN8, G1PDH_GEOSE;  A4IP94, G1PDH_GEOTN;  B9LUA0, G1PDH_HALLT;
DR   Q5V5G2, G1PDH_HALMA;  B0R3A6, G1PDH_HALS3;  Q9HS49, G1PDH_HALSA;
DR   Q18JW6, G1PDH_HALWD;  A2BN26, G1PDH_HYPBU;  A8ABP9, G1PDH_IGNH4;
DR   B1L7K1, G1PDH_KORCO;  A6UUD2, G1PDH_META3;  Q8TJU1, G1PDH_METAC;
DR   A7I9R4, G1PDH_METB6;  Q46FR7, G1PDH_METBF;  Q12X59, G1PDH_METBU;
DR   Q2FPC7, G1PDH_METHJ;  Q58122, G1PDH_METJA;  Q8TW08, G1PDH_METKA;
DR   A2ST19, G1PDH_METLZ;  A4FZY2, G1PDH_METM5;  A9A874, G1PDH_METM6;
DR   A6VIL2, G1PDH_METM7;  Q8PZA4, G1PDH_METMA;  A3CX71, G1PDH_METMJ;
DR   Q6M0P4, G1PDH_METMP;  B8GGP5, G1PDH_METPE;  A5UJW3, G1PDH_METS3;
DR   A4YIZ1, G1PDH_METS5;  Q2NFL8, G1PDH_METST;  P72010, G1PDH_METTH;
DR   A0B5P3, G1PDH_METTP;  A6URL4, G1PDH_METVS;  Q3ING6, G1PDH_NATPD;
DR   A9A2U8, G1PDH_NITMS;  Q6L0R7, G1PDH_PICTO;  Q9V0V0, G1PDH_PYRAB;
DR   Q8ZWP5, G1PDH_PYRAE;  A4WLW1, G1PDH_PYRAR;  A3MTM6, G1PDH_PYRCJ;
DR   Q8U147, G1PDH_PYRFU;  O59144, G1PDH_PYRHO;  A1RV58, G1PDH_PYRIL;
DR   Q5JH91, G1PDH_PYRKO;  A3DN28, G1PDH_STAMF;  Q4JB01, G1PDH_SULAC;
DR   C3N5P0, G1PDH_SULIA;  C4KHB6, G1PDH_SULIK;  C3MQ22, G1PDH_SULIL;
DR   C3MVE1, G1PDH_SULIM;  C3NHE5, G1PDH_SULIN;  C3NEA4, G1PDH_SULIY;
DR   Q9UXE7, G1PDH_SULSO;  P58460, G1PDH_SULTO;  Q9HJ16, G1PDH_THEAC;
DR   B1YCY7, G1PDH_THENV;  A1RZJ9, G1PDH_THEPD;  C6A2E4, G1PDH_THESM;
DR   Q979B1, G1PDH_THEVO;  Q0W4M8, G1PDH_UNCMA;
//
ID   1.1.1.262
DE   4-hydroxythreonine-4-phosphate dehydrogenase.
AN   4-(phosphohydroxy)-L-threonine dehydrogenase.
AN   L-threonine 4-phosphate dehydrogenase.
AN   NAD(+)-dependent threonine 4-phosphate dehydrogenase.
CA   4-(phosphonooxy)-L-threonine + NAD(+) = (2S)-2-amino-3-oxo-4-
CA   phosphonooxybutanoate + NADH.
CC   -!- The product of the reaction undergoes decarboxylation to give
CC       3-amino-2-oxopropyl phosphate.
CC   -!- In Escherichia coli, the coenzyme pyridoxal 5'-phosphate is
CC       synthesized de novo by a pathway that involves EC 1.2.1.72,
CC       EC 1.1.1.290, EC 2.6.1.52, EC 1.1.1.262, EC 2.6.99.2 and EC 1.4.3.5.
DR   Q89NF3, PDXA1_BRAJA;  Q9I5U4, PDXA1_PSEAE;  Q92QZ0, PDXA1_RHIME;
DR   P58715, PDXA1_SALTI;  P58717, PDXA1_SALTY;  Q89MT9, PDXA2_BRAJA;
DR   Q9I1Q5, PDXA2_PSEAE;  Q92X16, PDXA2_RHIME;  P58716, PDXA2_SALTI;
DR   P58718, PDXA2_SALTY;  Q92TP3, PDXA3_RHIME;  B7J3R1, PDXA_ACIF2 ;
DR   B5EL82, PDXA_ACIF5 ;  Q8UGD4, PDXA_AGRT5 ;  O67019, PDXA_AQUAE ;
DR   Q5P7J0, PDXA_AROAE ;  A1K9J6, PDXA_AZOSB ;  Q9RC88, PDXA_BACHD ;
DR   Q89ZK3, PDXA_BACTN ;  B2IDU5, PDXA_BEII9 ;  P65680, PDXA_BRUME ;
DR   P65681, PDXA_BRUSU ;  A4JHP8, PDXA_BURVG ;  A0RNS3, PDXA_CAMFF ;
DR   A8FMU4, PDXA_CAMJ8 ;  Q9PN58, PDXA_CAMJE ;  A1W0M2, PDXA_CAMJJ ;
DR   Q5HTM4, PDXA_CAMJR ;  Q9A7N4, PDXA_CAUCR ;  Q7NQA9, PDXA_CHRVO ;
DR   A8ALP8, PDXA_CITK8 ;  A7FVM3, PDXA_CLOB1 ;  C3KYY3, PDXA_CLOB6 ;
DR   A5I3X9, PDXA_CLOBH ;  C1FQK1, PDXA_CLOBJ ;  B1IGV8, PDXA_CLOBK ;
DR   A7GFE5, PDXA_CLOBL ;  B1KVV5, PDXA_CLOBM ;  Q47VJ9, PDXA_COLP3 ;
DR   Q475Q2, PDXA_CUPPJ ;  B7KAA8, PDXA_CYAP7 ;  B8FEI1, PDXA_DESAA ;
DR   C0QBU5, PDXA_DESAH ;  A8ZUN0, PDXA_DESOH ;  A7ZHE5, PDXA_ECO24 ;
DR   B7L4H5, PDXA_ECO55 ;  P58713, PDXA_ECO57 ;  B5YZ90, PDXA_ECO5E ;
DR   B7NHF8, PDXA_ECO7I ;  B7MNR1, PDXA_ECO81 ;  B7M0E9, PDXA_ECO8A ;
DR   C4ZPX8, PDXA_ECOBW ;  B1XC53, PDXA_ECODH ;  A7ZW04, PDXA_ECOHS ;
DR   Q8FL95, PDXA_ECOL6 ;  B1IRC4, PDXA_ECOLC ;  P19624, PDXA_ECOLI ;
DR   B7N7S7, PDXA_ECOLU ;  B6HZ33, PDXA_ECOSE ;  B1LFY8, PDXA_ECOSM ;
DR   A4W6F8, PDXA_ENT38 ;  Q47824, PDXA_ENTAG ;  B2VGP9, PDXA_ERWT9 ;
DR   Q2N8X0, PDXA_ERYLH ;  B7LVS5, PDXA_ESCF3 ;  Q8RGR0, PDXA_FUSNN ;
DR   B3E252, PDXA_GEOLS ;  Q39Q58, PDXA_GEOMG ;  Q5FNS3, PDXA_GLUOX ;
DR   Q17ZN0, PDXA_HELAH ;  B6JP92, PDXA_HELP2 ;  B5Z9L3, PDXA_HELPG ;
DR   Q1CR24, PDXA_HELPH ;  Q9ZJ28, PDXA_HELPJ ;  B2UVZ9, PDXA_HELPS ;
DR   O26103, PDXA_HELPY ;  A4G255, PDXA_HERAR ;  B4U950, PDXA_HYDS0 ;
DR   A6SV12, PDXA_JANMA ;  A1U6F9, PDXA_MARAV ;  Q0AQC2, PDXA_MARMM ;
DR   B7KYJ1, PDXA_METC4 ;  Q3V8A3, PDXA_METCA ;  A9VXC3, PDXA_METEP ;
DR   B1ZAJ4, PDXA_METPB ;  Q9JX42, PDXA_NEIMA ;  Q9K1F9, PDXA_NEIMB ;
DR   P58711, PDXA_NOSS1 ;  Q8CUU4, PDXA_OCEIH ;  A1B0G5, PDXA_PARDP ;
DR   Q9CKG8, PDXA_PASMU ;  C0QTA7, PDXA_PERMH ;  B4S6L0, PDXA_PROA2 ;
DR   Q6AB12, PDXA_PROAC ;  Q15QB2, PDXA_PSEA6 ;  Q3IFD2, PDXA_PSEHT ;
DR   A4XZJ3, PDXA_PSEMY ;  Q88QT5, PDXA_PSEPK ;  Q88A45, PDXA_PSESM ;
DR   A4VHI1, PDXA_PSEU5 ;  P58714, PDXA_RALSO ;  Q984S6, PDXA_RHILO ;
DR   Q7UMZ2, PDXA_RHOBA ;  Q3V7R9, PDXA_RHOPA ;  B3Q9S3, PDXA_RHOPT ;
DR   Q164G2, PDXA_ROSDO ;  Q21MS9, PDXA_SACD2 ;  A9MQG1, PDXA_SALAR ;
DR   A8G9P1, PDXA_SERP5 ;  Q12K60, PDXA_SHEDO ;  Q07YJ9, PDXA_SHEFN ;
DR   Q8EB94, PDXA_SHEON ;  B2U260, PDXA_SHIB3 ;  Q326I1, PDXA_SHIBS ;
DR   Q32K42, PDXA_SHIDS ;  Q0T8E3, PDXA_SHIF8 ;  Q83SQ1, PDXA_SHIFL ;
DR   Q3Z5V7, PDXA_SHISS ;  Q1GI38, PDXA_SILST ;  Q2NVX5, PDXA_SODGM ;
DR   O85987, PDXA_SPHAR ;  B4SK42, PDXA_STRM5 ;  B2FPG6, PDXA_STRMK ;
DR   Q30S58, PDXA_SULDN ;  B2V9E6, PDXA_SULSY ;  Q3V818, PDXA_SYMTH ;
DR   A0LIN6, PDXA_SYNFM ;  Q2JSC8, PDXA_SYNJA ;  Q2JKQ8, PDXA_SYNJB ;
DR   A5GPX7, PDXA_SYNR3 ;  Q55982, PDXA_SYNY3 ;  Q8DHB4, PDXA_THEEB ;
DR   B8GMX6, PDXA_THISH ;  Q9KUS1, PDXA_VIBCH ;  Q87ST5, PDXA_VIBPA ;
DR   Q8DED3, PDXA_VIBVU ;  Q7MP85, PDXA_VIBVY ;  Q8D3I2, PDXA_WIGBR ;
DR   Q8PP24, PDXA_XANAC ;  Q4UR40, PDXA_XANC8 ;  B0RUI2, PDXA_XANCB ;
DR   Q8PCE2, PDXA_XANCP ;  B2SPT4, PDXA_XANOP ;  A7IJ81, PDXA_XANP2 ;
DR   Q9PF39, PDXA_XYLFA ;  Q87AJ1, PDXA_XYLFT ;  A1JJF5, PDXA_YERE8 ;
DR   A7FMC0, PDXA_YERP3 ;  B2K488, PDXA_YERPB ;  P58719, PDXA_YERPE ;
DR   A9QZY9, PDXA_YERPG ;  Q3V7Q4, PDXA_YERPS ;  B1JKY2, PDXA_YERPY ;
DR   Q5NMX3, PDXA_ZYMMO ;
//
ID   1.1.1.263
DE   1,5-anhydro-D-fructose reductase.
AN   AF reductase.
CA   1,5-anhydro-D-glucitol + NADP(+) = 1,5-anhydro-D-fructose + NADPH.
CC   -!- Also reduces pyridine-3-aldehyde and 2,3-butanedione.
CC   -!- Acetaldehyde, 2-dehydroglucose (glucosone) and glucuronate are poor
CC       substrates, but there is no detectable action on glucose, mannose and
CC       fructose.
DR   Q96JD6, AKCL2_HUMAN;  Q4R802, AKCL2_MACFA;  Q9DCT1, AKCL2_MOUSE;
DR   P82125, AKCL2_PIG  ;  Q5U1Y4, AKCL2_RAT  ;
//
ID   1.1.1.264
DE   L-idonate 5-dehydrogenase.
CA   L-idonate + NAD(P)(+) = 5-dehydrogluconate + NAD(P)H.
CF   Zinc.
CC   -!- The enzyme from Escherichia coli cannot oxidize D-gluconate to form
CC       5-dehydrogluconate, a reaction that is catalyzed by EC 1.1.1.69.
PR   PROSITE; PDOC00058;
DR   P39346, IDND_ECOLI ;
//
ID   1.1.1.265
DE   3-methylbutanal reductase.
CA   3-methylbutanol + NAD(P)(+) = 3-methylbutanal + NAD(P)H.
CC   -!- The enzyme purified from Saccharomyces cerevisiae catalyzes the
CC       reduction of a number of straight-chain and branched aldehydes,
CC       as well as some aromatic aldehydes.
//
ID   1.1.1.266
DE   dTDP-4-dehydro-6-deoxyglucose reductase.
AN   dTDP-4-keto-6-deoxyglucose reductase.
CA   dTDP-D-fucose + NADP(+) = dTDP-4-dehydro-6-deoxy-D-glucose + NADPH.
CC   -!- The enzyme from the Gram-negative bacterium Actinobacillus
CC       actinomycetemcomitans forms activated fucose for incorporation into
CC       capsular polysaccharide.
//
ID   1.1.1.267
DE   1-deoxy-D-xylulose-5-phosphate reductoisomerase.
AN   1-deoxyxylulose-5-phosphate reductoisomerase.
AN   DXP-reductoisomerase.
CA   2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose
CA   5-phosphate + NADPH.
CF   Cobalt or manganese or magnesium.
CC   -!- The enzyme from several eubacteria, including Escherichia coli, forms
CC       part of an alternative nonmevalonate pathway for terpenoid
CC       biosynthesis.
CC   -!- The mechanism has been shown to be a retroaldol/aldol reaction.
DR   Q81N10, DXR1_BACAN ;  Q81B49, DXR1_BACCR ;  Q638M6, DXR1_BACCZ ;
DR   Q6HG59, DXR1_BACHK ;  Q81WL4, DXR2_BACAN ;  Q819Y3, DXR2_BACCR ;
DR   Q636K5, DXR2_BACCZ ;  Q6HEZ4, DXR2_BACHK ;  B0CD21, DXR_ACAM1  ;
DR   Q6FCG9, DXR_ACIAD  ;  B7H1U5, DXR_ACIB3  ;  B7I9U9, DXR_ACIB5  ;
DR   B2I325, DXR_ACIBC  ;  B0VMU8, DXR_ACIBS  ;  A3M654, DXR_ACIBT  ;
DR   B0V6F3, DXR_ACIBY  ;  B7J9P7, DXR_ACIF2  ;  B5EQQ4, DXR_ACIF5  ;
DR   A3MZC4, DXR_ACTP2  ;  B0BTR0, DXR_ACTPJ  ;  A0KHG9, DXR_AERHH  ;
DR   A4SQH6, DXR_AERS4  ;  B9JBW0, DXR_AGRRK  ;  Q8UC86, DXR_AGRT5  ;
DR   B9JTP4, DXR_AGRVS  ;  B6EK51, DXR_ALISL  ;  A8MHH5, DXR_ALKOO  ;
DR   B8J6S7, DXR_ANAD2  ;  B9KIT5, DXR_ANAMF  ;  Q5PAI9, DXR_ANAMM  ;
DR   Q2GKQ8, DXR_ANAPZ  ;  B4UD63, DXR_ANASK  ;  Q3MDL2, DXR_ANAVT  ;
DR   O66722, DXR_AQUAE  ;  Q9XFS9, DXR_ARATH  ;  Q5NZG9, DXR_AROAE  ;
DR   A1R4Z8, DXR_ARTAT  ;  B8HFR2, DXR_ARTCA  ;  A0JUS3, DXR_ARTS2  ;
DR   A7Z4S6, DXR_BACA2  ;  Q732P8, DXR_BACC1  ;  C1EP45, DXR_BACC3  ;
DR   B7HLF4, DXR_BACC7  ;  B9IVB0, DXR_BACCQ  ;  Q5L9P6, DXR_BACFN  ;
DR   Q64PY9, DXR_BACFR  ;  Q9KA69, DXR_BACHD  ;  Q65JJ3, DXR_BACLD  ;
DR   A8FDB9, DXR_BACP2  ;  Q5WFT4, DXR_BACSK  ;  O31753, DXR_BACSU  ;
DR   Q8A684, DXR_BACTN  ;  A6L0W8, DXR_BACV8  ;  Q1LSV3, DXR_BAUCH  ;
DR   C5BWT4, DXR_BEUC1  ;  B3DQ62, DXR_BIFLD  ;  Q8G7Y7, DXR_BIFLO  ;
DR   B7GQ02, DXR_BIFLS  ;  Q7VRE2, DXR_BLOFL  ;  Q493C8, DXR_BLOPB  ;
DR   Q2L155, DXR_BORA1  ;  Q7WJ88, DXR_BORBR  ;  Q7WA54, DXR_BORPA  ;
DR   A9INU2, DXR_BORPD  ;  Q7VYC4, DXR_BORPE  ;  Q89KP9, DXR_BRAJA  ;
DR   A5EK49, DXR_BRASB  ;  A4YVG0, DXR_BRASO  ;  C0ZF60, DXR_BREBN  ;
DR   B8D932, DXR_BUCA5  ;  P57329, DXR_BUCAI  ;  Q8K9S7, DXR_BUCAP  ;
DR   B8D7D6, DXR_BUCAT  ;  B1YS68, DXR_BURA4  ;  Q1BHH6, DXR_BURCA  ;
DR   B1JUE4, DXR_BURCC  ;  A0K8D7, DXR_BURCH  ;  B4ECM5, DXR_BURCJ  ;
DR   Q0BE21, DXR_BURCM  ;  A9AIM0, DXR_BURM1  ;  A3MKT7, DXR_BURM7  ;
DR   A2SB78, DXR_BURM9  ;  Q62JD0, DXR_BURMA  ;  A1V563, DXR_BURMS  ;
DR   A3NWM5, DXR_BURP0  ;  Q3JR34, DXR_BURP1  ;  A3NAU2, DXR_BURP6  ;
DR   B2JIC0, DXR_BURP8  ;  B2T5I8, DXR_BURPP  ;  Q63T18, DXR_BURPS  ;
DR   Q39F49, DXR_BURS3  ;  Q2SWZ2, DXR_BURTA  ;  A4JF69, DXR_BURVG  ;
DR   Q13XC2, DXR_BURXL  ;  A7H0K4, DXR_CAMC5  ;  A0RMI1, DXR_CAMFF  ;
DR   A7HZP3, DXR_CAMHC  ;  A8FN24, DXR_CAMJ8  ;  A7H243, DXR_CAMJD  ;
DR   Q9PMV3, DXR_CAMJE  ;  A1W0W2, DXR_CAMJJ  ;  Q5HT65, DXR_CAMJR  ;
DR   B9KE50, DXR_CAMLR  ;  Q3AB86, DXR_CARHZ  ;  B8GWR7, DXR_CAUCN  ;
DR   Q9A709, DXR_CAUCR  ;  B3PBQ4, DXR_CELJU  ;  Q5L651, DXR_CHLAB  ;
DR   Q3AUE4, DXR_CHLCH  ;  Q823G9, DXR_CHLCV  ;  Q254F0, DXR_CHLFF  ;
DR   B3EE57, DXR_CHLL2  ;  Q9PKW8, DXR_CHLMU  ;  B3EK13, DXR_CHLPB  ;
DR   A1BJT7, DXR_CHLPD  ;  Q9Z8J8, DXR_CHLPN  ;  B0B9H9, DXR_CHLT2  ;
DR   B3QXY0, DXR_CHLT3  ;  Q3KMV0, DXR_CHLTA  ;  B0BB58, DXR_CHLTB  ;
DR   Q8KG43, DXR_CHLTE  ;  O84074, DXR_CHLTR  ;  Q7NVY8, DXR_CHRVO  ;
DR   Q97I58, DXR_CLOAB  ;  A7FW01, DXR_CLOB1  ;  C3L0C4, DXR_CLOB6  ;
DR   A6LSP7, DXR_CLOB8  ;  B2V4G1, DXR_CLOBA  ;  B2TJ47, DXR_CLOBB  ;
DR   A5I4K2, DXR_CLOBH  ;  C1FS67, DXR_CLOBJ  ;  B1II57, DXR_CLOBK  ;
DR   A7GG14, DXR_CLOBL  ;  B1KWL5, DXR_CLOBM  ;  B8I6D9, DXR_CLOCE  ;
DR   Q185R8, DXR_CLOD6  ;  B9E1J4, DXR_CLOK1  ;  A5N834, DXR_CLOK5  ;
DR   A0Q0R4, DXR_CLONN  ;  Q0TPQ9, DXR_CLOP1  ;  Q8XJR1, DXR_CLOPE  ;
DR   A9KMX2, DXR_CLOPH  ;  Q0SSC6, DXR_CLOPS  ;  Q895K5, DXR_CLOTE  ;
DR   A3DE52, DXR_CLOTH  ;  Q485G4, DXR_COLP3  ;  Q6NGL1, DXR_CORDI  ;
DR   Q8FP80, DXR_COREF  ;  A4QF22, DXR_CORGB  ;  Q8NP10, DXR_CORGL  ;
DR   Q4JV26, DXR_CORJK  ;  Q0KA22, DXR_CUPNH  ;  Q470E3, DXR_CUPPJ  ;
DR   B3R2B1, DXR_CUPTR  ;  B1WNP5, DXR_CYAA5  ;  B8HVK1, DXR_CYAP4  ;
DR   B7KAT5, DXR_CYAP7  ;  B7K5G6, DXR_CYAP8  ;  Q47F86, DXR_DECAR  ;
DR   Q9RU84, DXR_DEIRA  ;  B1I2I8, DXR_DESAP  ;  Q313H2, DXR_DESDG  ;
DR   B8FR31, DXR_DESHD  ;  Q24UG4, DXR_DESHY  ;  A8ZTM6, DXR_DESOH  ;
DR   Q6AP35, DXR_DESPS  ;  A4J5Y5, DXR_DESRM  ;  Q72DR3, DXR_DESVH  ;
DR   A1VFB6, DXR_DESVV  ;  Q8X8Y1, DXR_ECO57  ;  P45568, DXR_ECOLI  ;
DR   C5BHC1, DXR_EDWI9  ;  Q3YRZ5, DXR_EHRCJ  ;  Q2GGR4, DXR_EHRCR  ;
DR   Q5FHA4, DXR_EHRRG  ;  Q5HB55, DXR_EHRRW  ;  B2KCJ9, DXR_ELUMP  ;
DR   Q6D8D9, DXR_ERWCT  ;  B2VE12, DXR_ERWT9  ;  C4Z5K1, DXR_EUBE2  ;
DR   C4ZA70, DXR_EUBR3  ;  B1YI70, DXR_EXIS2  ;  C4L656, DXR_EXISA  ;
DR   A7HLL7, DXR_FERNB  ;  Q14G49, DXR_FRAT1  ;  A7NAP0, DXR_FRATF  ;
DR   Q2A4P9, DXR_FRATH  ;  B2SFW7, DXR_FRATM  ;  A0Q7Y5, DXR_FRATN  ;
DR   Q0BN25, DXR_FRATO  ;  Q5NEP6, DXR_FRATT  ;  A4IWJ1, DXR_FRATW  ;
DR   Q8R622, DXR_FUSNN  ;  B5EHV5, DXR_GEOBB  ;  Q5L0J6, DXR_GEOKA  ;
DR   B3E7B0, DXR_GEOLS  ;  Q39W82, DXR_GEOMG  ;  B9M5C0, DXR_GEOSF  ;
DR   Q74BW4, DXR_GEOSL  ;  C6E518, DXR_GEOSM  ;  C5D9C1, DXR_GEOSW  ;
DR   A5G7W2, DXR_GEOUR  ;  Q7NID1, DXR_GLOVI  ;  Q5FPZ1, DXR_GLUOX  ;
DR   Q7VM27, DXR_HAEDU  ;  Q4QM93, DXR_HAEI8  ;  A5UDR7, DXR_HAEIE  ;
DR   A5UHV9, DXR_HAEIG  ;  P44055, DXR_HAEIN  ;  B8F4X2, DXR_HAEPS  ;
DR   Q2SBQ3, DXR_HAHCH  ;  B8CW61, DXR_HALOH  ;  Q7VIT0, DXR_HELHP  ;
DR   B0THN7, DXR_HELMI  ;  B6JKE8, DXR_HELP2  ;  B5Z9Y5, DXR_HELPG  ;
DR   Q1CUT8, DXR_HELPH  ;  Q9ZML6, DXR_HELPJ  ;  B2US45, DXR_HELPS  ;
DR   P56139, DXR_HELPY  ;  A4G4S7, DXR_HERAR  ;  Q5QUF4, DXR_IDILO  ;
DR   A6SZP5, DXR_JANMA  ;  Q28PJ0, DXR_JANSC  ;  Q9AJD7, DXR_KITGR  ;
DR   C1D9F0, DXR_LARHH  ;  Q1MRD4, DXR_LAWIP  ;  Q6AEY1, DXR_LEIXX  ;
DR   B0SDN1, DXR_LEPBA  ;  Q04U66, DXR_LEPBJ  ;  Q053M9, DXR_LEPBL  ;
DR   B0SM60, DXR_LEPBP  ;  Q72U08, DXR_LEPIC  ;  Q8F146, DXR_LEPIN  ;
DR   Q92C37, DXR_LISIN  ;  C1L2M3, DXR_LISMC  ;  Q720A5, DXR_LISMF  ;
DR   B8DG10, DXR_LISMH  ;  Q8Y7G4, DXR_LISMO  ;  A0AIB8, DXR_LISW6  ;
DR   B1HQZ7, DXR_LYSSC  ;  B9EBE2, DXR_MACCJ  ;  Q65R75, DXR_MANSM  ;
DR   Q9XES0, DXR_MENPI  ;  Q60BA4, DXR_METCA  ;  Q1H145, DXR_METFK  ;
DR   B0JWW6, DXR_MICAN  ;  Q2RJN4, DXR_MOOTA  ;  A0QJ14, DXR_MYCA1  ;
DR   P64013, DXR_MYCBO  ;  A1KML5, DXR_MYCBP  ;  C1AFY6, DXR_MYCBT  ;
DR   Q7NC17, DXR_MYCGA  ;  B8ZRU7, DXR_MYCLB  ;  Q9CBU3, DXR_MYCLE  ;
DR   B2HJP9, DXR_MYCMM  ;  Q73VS1, DXR_MYCPA  ;  Q8EWQ6, DXR_MYCPE  ;
DR   A0QVH7, DXR_MYCS2  ;  A5U6M4, DXR_MYCTA  ;  P64012, DXR_MYCTU  ;
DR   A0PQ95, DXR_MYCUA  ;  B9L7Q2, DXR_NAUPA  ;  Q5F5X0, DXR_NEIG1  ;
DR   Q9JX33, DXR_NEIMA  ;  Q9K1G8, DXR_NEIMB  ;  Q0AEI0, DXR_NITEC  ;
DR   Q82U01, DXR_NITEU  ;  Q1QMN1, DXR_NITHX  ;  Q2YBA1, DXR_NITMU  ;
DR   Q3JCW9, DXR_NITOC  ;  Q3SRH8, DXR_NITWN  ;  Q5YS72, DXR_NOCFA  ;
DR   B2ITX3, DXR_NOSP7  ;  Q8YP49, DXR_NOSS1  ;  B6JH72, DXR_OLICO  ;
DR   Q8W250, DXR_ORYSJ  ;  A1B969, DXR_PARDP  ;  Q6MEL5, DXR_PARUW  ;
DR   P57985, DXR_PASMU  ;  C6DAI7, DXR_PECCP  ;  Q3B6R4, DXR_PELLD  ;
DR   B4SAR7, DXR_PELPB  ;  A1AQN8, DXR_PELPD  ;  A5D2U3, DXR_PELTS  ;
DR   Q4FM64, DXR_PELUB  ;  C0QTC4, DXR_PERMH  ;  Q7N8P3, DXR_PHOLL  ;
DR   Q6LN30, DXR_PHOPR  ;  B2RJX5, DXR_PORG3  ;  Q7MUW3, DXR_PORGI  ;
DR   B4S387, DXR_PROA2  ;  Q6A7K8, DXR_PROAC  ;  A2C3T8, DXR_PROM1  ;
DR   A2BXK2, DXR_PROM5  ;  Q319Z8, DXR_PROM9  ;  Q7VB62, DXR_PROMA  ;
DR   B4F2C9, DXR_PROMH  ;  Q7V6J8, DXR_PROMM  ;  Q7V0W0, DXR_PROMP  ;
DR   Q46JT6, DXR_PROMT  ;  A4SCF3, DXR_PROVI  ;  Q48F65, DXR_PSE14  ;
DR   A6V1D8, DXR_PSEA7  ;  B7V7G3, DXR_PSEA8  ;  Q02RC2, DXR_PSEAB  ;
DR   Q9KGU6, DXR_PSEAE  ;  Q4KHH0, DXR_PSEF5  ;  C3K601, DXR_PSEFS  ;
DR   A4XWT5, DXR_PSEMY  ;  A5W844, DXR_PSEP1  ;  Q3KHA6, DXR_PSEPF  ;
DR   B0KSA5, DXR_PSEPG  ;  Q88MH4, DXR_PSEPK  ;  B1JBQ4, DXR_PSEPW  ;
DR   Q886N7, DXR_PSESM  ;  Q4ZWS2, DXR_PSEU2  ;  A4VJS7, DXR_PSEU5  ;
DR   Q4FRH9, DXR_PSYA2  ;  Q1QA16, DXR_PSYCK  ;  A1SYV7, DXR_PSYIN  ;
DR   A5WGE7, DXR_PSYWF  ;  Q1LNF2, DXR_RALME  ;  B2UB12, DXR_RALPJ  ;
DR   Q8XZI5, DXR_RALSO  ;  B3PQ37, DXR_RHIE6  ;  Q2K3K0, DXR_RHIEC  ;
DR   Q1MB26, DXR_RHIL3  ;  Q92LP6, DXR_RHIME  ;  C3M9M8, DXR_RHISN  ;
DR   Q7URM5, DXR_RHOBA  ;  B6ISU5, DXR_RHOCS  ;  Q2IW86, DXR_RHOP2  ;
DR   Q07NI7, DXR_RHOP5  ;  Q6N5Q6, DXR_RHOPA  ;  Q215E3, DXR_RHOPB  ;
DR   Q136B0, DXR_RHOPS  ;  B3Q7J8, DXR_RHOPT  ;  A3PJG0, DXR_RHOS1  ;
DR   Q3J2X1, DXR_RHOS4  ;  A4WUH5, DXR_RHOS5  ;  B9KRU3, DXR_RHOSK  ;
DR   Q0S275, DXR_RHOSR  ;  A1AV71, DXR_RUTMC  ;  Q21HH8, DXR_SACD2  ;
DR   Q57T35, DXR_SALCH  ;  Q5PD59, DXR_SALPA  ;  Q8Z9A6, DXR_SALTI  ;
DR   Q8ZRP3, DXR_SALTY  ;  A8GIE2, DXR_SERP5  ;  A1S4P6, DXR_SHEAM  ;
DR   B8E7R0, DXR_SHEB2  ;  A3D2L1, DXR_SHEB5  ;  A9KUL1, DXR_SHEB9  ;
DR   Q085D6, DXR_SHEFN  ;  B0TP77, DXR_SHEHH  ;  A3QG97, DXR_SHELP  ;
DR   Q8EGG9, DXR_SHEON  ;  A8H6L0, DXR_SHEPA  ;  B8CQ79, DXR_SHEPW  ;
DR   A0KZ17, DXR_SHESA  ;  A8FY36, DXR_SHESH  ;  Q0HGW1, DXR_SHESM  ;
DR   Q0HT68, DXR_SHESR  ;  B1KNT7, DXR_SHEWM  ;  Q83MD3, DXR_SHIFL  ;
DR   Q5LSU9, DXR_SILPO  ;  Q1GGS3, DXR_SILST  ;  A6UDH9, DXR_SINMW  ;
DR   Q2NRL1, DXR_SODGM  ;  Q01QM3, DXR_SOLUE  ;  Q82K41, DXR_STRAW  ;
DR   Q9KYS1, DXR_STRCO  ;  B2V847, DXR_SULSY  ;  Q67PA9, DXR_SYMTH  ;
DR   Q31N26, DXR_SYNE7  ;  Q2JXQ9, DXR_SYNJA  ;  Q2JM39, DXR_SYNJB  ;
DR   Q9RCT1, DXR_SYNP6  ;  Q7U8C3, DXR_SYNPX  ;  Q0IBN9, DXR_SYNS3  ;
DR   Q3AZ20, DXR_SYNS9  ;  Q3AI71, DXR_SYNSC  ;  Q55663, DXR_SYNY3  ;
DR   Q8DK30, DXR_THEEB  ;  A8F4Z0, DXR_THELT  ;  Q9WZZ1, DXR_THEMA  ;
DR   B9KA80, DXR_THENN  ;  A5IIP4, DXR_THEP1  ;  B0K9Q9, DXR_THEP3  ;
DR   B0K1E5, DXR_THEPX  ;  B9L006, DXR_THERP  ;  Q72KE2, DXR_THET2  ;
DR   Q5SJZ6, DXR_THET8  ;  Q8RA28, DXR_THETN  ;  B5YI09, DXR_THEYD  ;
DR   C4L858, DXR_TOLAT  ;  Q73K78, DXR_TREDE  ;  O83610, DXR_TREPA  ;
DR   Q83IC8, DXR_TROW8  ;  Q83GY8, DXR_TROWT  ;  B1H060, DXR_UNCTG  ;
DR   A5CY29, DXR_VESOH  ;  A5F615, DXR_VIBC3  ;  Q9KPV8, DXR_VIBCH  ;
DR   C3LQ26, DXR_VIBCM  ;  Q5E3E5, DXR_VIBF1  ;  B5F9X0, DXR_VIBFM  ;
DR   A7MXZ4, DXR_VIBHB  ;  Q87ME3, DXR_VIBPA  ;  Q8DBF5, DXR_VIBVU  ;
DR   Q7MIG6, DXR_VIBVY  ;  Q8D2G6, DXR_WIGBR  ;  Q73GG3, DXR_WOLPM  ;
DR   B3CN89, DXR_WOLPP  ;  Q7M9M7, DXR_WOLSU  ;  Q5GTA4, DXR_WOLTR  ;
DR   C0R414, DXR_WOLWR  ;  Q8PML1, DXR_XANAC  ;  Q3BVL0, DXR_XANC5  ;
DR   Q4USQ4, DXR_XANC8  ;  B0RW72, DXR_XANCB  ;  Q8PAV9, DXR_XANCP  ;
DR   Q2P4B2, DXR_XANOM  ;  B2SR05, DXR_XANOP  ;  Q5H1E7, DXR_XANOR  ;
DR   B2I7P4, DXR_XYLF2  ;  Q9PEI0, DXR_XYLFA  ;  B0U242, DXR_XYLFM  ;
DR   Q87EH9, DXR_XYLFT  ;  A1JP78, DXR_YERE8  ;  A7FFH3, DXR_YERP3  ;
DR   Q1CAN0, DXR_YERPA  ;  B2JZ30, DXR_YERPB  ;  Q8ZH62, DXR_YERPE  ;
DR   A9R392, DXR_YERPG  ;  Q1CFF1, DXR_YERPN  ;  A4TL87, DXR_YERPP  ;
DR   Q667J3, DXR_YERPS  ;  B1JQG4, DXR_YERPY  ;  Q9X5F2, DXR_ZYMMO  ;
//
ID   1.1.1.268
DE   2-(R)-hydroxypropyl-CoM dehydrogenase.
AN   2-(2-(R)-hydroxypropylthio)ethanesulfonate dehydrogenase.
CA   2-(R)-hydroxypropyl-CoM + NAD(+) = 2-oxopropyl-CoM + NADH.
CC   -!- Highly specific for (R)-2-hydroxyalkyl thioethers of CoM, in contrast
CC       to EC 1.1.1.269, which is highly specific for the (S)-enantiomer.
CC   -!- Forms component III of a four-component enzyme system (comprising
CC       EC 4.4.1.23 (component I), EC 1.8.1.5 (component II), EC 1.1.1.268
CC       (component III) and EC 1.1.1.269 (component IV)) that is involved in
CC       epoxyalkane carboxylation in Xanthobacter sp. strain Py2.
DR   Q56840, HCDR_XANP2 ;
//
ID   1.1.1.269
DE   2-(S)-hydroxypropyl-CoM dehydrogenase.
AN   2-(2-(S)-hydroxypropylthio)ethanesulfonate dehydrogenase.
CA   2-(S)-hydroxypropyl-CoM + NAD(+) = 2-oxopropyl-CoM + NADH.
CC   -!- Highly specific for (S)-2-hydroxyalkyl thioethers of CoM, in contrast
CC       to EC 1.1.1.268, which is highly specific for the (R)-enantiomer.
CC   -!- Forms component IV of a four-component enzyme system (comprising
CC       EC 4.4.1.23 (component I), EC 1.8.1.5 (component II), EC 1.1.1.268
CC       (component III) and EC 1.1.1.269 (component IV)) that is involved in
CC       epoxyalkane carboxylation in Xanthobacter sp. strain Py2.
DR   Q56841, HCDS_XANP2 ;
//
ID   1.1.1.270
DE   3-keto-steroid reductase.
AN   3-KSR.
CA   4-alpha-methyl-5-alpha-cholest-7-en-3-beta-ol + NADP(+) = 4-alpha-methyl-
CA   5-alpha-cholest-7-en-3-one + NADPH.
CC   -!- Also acts on 5-alpha-cholest-7-en-3-one.
DR   P56937, DHB7_HUMAN ;  O88736, DHB7_MOUSE ;  Q62904, DHB7_RAT   ;
DR   Q74ZZ0, ERG27_ASHGO;  Q874K0, ERG27_CANAL;  Q6FIV3, ERG27_CANGA;
DR   Q6BNP0, ERG27_DEBHA;  Q6CJC2, ERG27_KLULA;  O74732, ERG27_SCHPO;
DR   Q6CE88, ERG27_YARLI;  Q12452, ERG27_YEAST;
//
ID   1.1.1.271
DE   GDP-L-fucose synthase.
AN   GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase.
AN   GDP-fucose synthetase.
CA   GDP-L-fucose + NADP(+) = GDP-4-dehydro-6-deoxy-D-mannose + NADPH.
CC   -!- Both human and Escherichia coli enzymes can use NADH in place of
CC       NADPH to a slight extent.
DR   O49213, FCL1_ARATH ;  Q67WR2, FCL1_ORYSJ ;  Q9LMU0, FCL2_ARATH ;
DR   Q67WR5, FCL2_ORYSJ ;  Q8K3X2, FCL_CRIGR  ;  Q55C77, FCL_DICDI  ;
DR   Q9W1X8, FCL_DROME  ;  P32055, FCL_ECOLI  ;  Q13630, FCL_HUMAN  ;
DR   P23591, FCL_MOUSE  ;  Q5RBE5, FCL_PONAB  ;
//
ID   1.1.1.272
DE   (R)-2-hydroxyacid dehydrogenase.
AN   (R)-sulfolactate:NAD(P)(+) oxidoreductase.
AN   L-sulfolactate dehydrogenase.
CA   (2R)-3-sulfolactate + NAD(P)(+) = 3-sulfopyruvate + NAD(P)H.
CC   -!- This dehydrogenase also acts on (S)-malate and (S)-2-hydroxyglutarate
CC       i.e. with the same configuration as (R)-sulfolactate.
DR   Q58820, COMC_METJA ;  P16142, MDH_METFV  ;
//
ID   1.1.1.273
DE   Vellosimine dehydrogenase.
CA   10-deoxysarpagine + NADP(+) = vellosimine + NADPH.
CC   -!- Also acts on related alkaloids with an endo-aldehyde group such as
CC       vellosimine (same stereochemistry at C-16) but only slight activity
CC       with exo-aldehydes (epimeric at C-16).
CC   -!- Detected in many cell suspension cultures of plants from the family
CC       Apocynaceae.
//
ID   1.1.1.274
DE   2,5-didehydrogluconate reductase.
AN   2,5-diketo-D-gluconate reductase.
CA   2-dehydro-D-gluconate + NADP(+) = 2,5-didehydro-D-gluconate + NADPH.
CC   -!- Key enzyme in the microbial production of ascorbate.
CC   -!- Can also reduce ethyl 2-methylacetoacetate stereoselectively to ethyl
CC       (2R)-methyl-(3S)-hydroxybutanoate and can also accept some other
CC       beta-keto esters.
CC   -!- The identification of a bacterial beta-keto ester reductase as a 2,5-
CC       didehydrogluconate reductase links two previously separate areas of
CC       biocatalysis, i.e., asymmetric carbonyl reduction and microbial
CC       vitamin C production.
PR   PROSITE; PDOC00061;
DR   P06632, DKGA_CORSC ;  Q8XBT6, DKGA_ECO57 ;  Q46857, DKGA_ECOLI ;
DR   P58744, DKGA_SALTI ;  Q8ZM06, DKGA_SALTY ;  Q8ZI40, DKGA_YERPE ;
DR   P15339, DKGB_CORSS ;  Q8X7Z7, DKGB_ECO57 ;  P30863, DKGB_ECOLI ;
DR   Q8Z988, DKGB_SALTI ;  Q8ZRM7, DKGB_SALTY ;  Q8ZH36, DKGB_YERPE ;
//
ID   1.1.1.275
DE   (+)-trans-carveol dehydrogenase.
AN   Carveol dehydrogenase.
CA   (+)-trans-carveol + NAD(+) = (+)-(S)-carvone + NADH.
CC   -!- NADP(+) cannot replace NAD(+).
CC   -!- Forms part of the monoterpenoid biosynthesis pathway in Carum carvi
CC       (caraway) seeds.
//
ID   1.1.1.276
DE   Serine 3-dehydrogenase.
CA   L-serine + NADP(+) = 2-ammoniomalonate semialdehyde + NADPH.
CC   -!- The product 2-ammoniomalonate semialdehyde is spontaneously converted
CC       into 2-aminoacetaldehyde and CO(2).
CC   -!- NAD(+) cannot replace NADP(+).
PR   PROSITE; PDOC00060;
DR   Q8U8I2, SDH_AGRT5  ;  Q9KWN1, SDH_RHIRD  ;
//
ID   1.1.1.277
DE   3-beta-hydroxy-5-beta-steroid dehydrogenase.
AN   3-beta-hydroxysteroid 5-beta-oxidoreductase.
AN   3-beta-hydroxysteroid 5-beta-progesterone oxidoreductase.
CA   3-beta-hydroxy-5-beta-pregnane-20-one + NADP(+) = 5-beta-pregnan-3,20-
CA   dione + NADPH.
//
ID   1.1.1.278
DE   3-beta-hydroxy-5-alpha-steroid dehydrogenase.
CA   3-beta-hydroxy-5-alpha-pregnane-20-one + NADP(+) = 5-alpha-pregnan-3,20-
CA   dione + NADPH.
//
ID   1.1.1.279
DE   (R)-3-hydroxyacid-ester dehydrogenase.
AN   3-oxo ester (R)-reductase.
CA   Ethyl (R)-3-hydroxyhexanoate + NADP(+) = ethyl 3-oxohexanoate + NADPH.
CC   -!- Also acts on ethyl (R)-3-oxobutanoate and some other (R)-3-hydroxy
CC       acid esters.
CC   -!- The (R)- symbol is allotted on the assumption that no substituents
CC       change the order of priority from O-3>C-2>C-4.
CC   -!- A subunit of Saccharomyces cerevisiae EC 2.3.1.86.
CC   -!- Cf. EC 1.1.1.280.
CC   -!- Formerly EC 1.2.1.55.
//
ID   1.1.1.280
DE   (S)-3-hydroxyacid-ester dehydrogenase.
AN   3-oxo ester (S)-reductase.
CA   Ethyl (S)-3-hydroxyhexanoate + NADP(+) = ethyl 3-oxohexanoate + NADPH.
CC   -!- Also acts on 4-oxo- and 5-oxo-fatty acids and their esters.
CC   -!- Cf. EC 1.1.1.279.
CC   -!- Formerly EC 1.2.1.56.
//
ID   1.1.1.281
DE   GDP-4-dehydro-6-deoxy-D-mannose reductase.
AN   GDP-4-keto-6-deoxy-D-mannose reductase.
AN   GDP-6-deoxy-D-lyxo-4-hexulose reductase.
CA   GDP-6-deoxy-D-mannose + NAD(P)(+) = GDP-4-dehydro-6-deoxy-D-mannose +
CA   NAD(P)H.
CC   -!- Differs from EC 1.1.1.187 in that the only product formed is GDP-D-
CC       rhamnose (GDP-6-deoxy-D-mannose).
CC   -!- D-rhamnose is a constituent of lipopolysaccharides of Gram-negative
CC       plant and human pathogenic bacteria.
//
ID   1.1.1.282
DE   Quinate/shikimate dehydrogenase.
CA   (1) L-quinate + NAD(P)(+) = 3-dehydroquinate + NAD(P)H.
CA   (2) Shikimate + NAD(P)(+) = 3-dehydroshikimate + NAD(P)H.
CC   -!- This is the second shikimate dehydrogenase enzyme found in
CC       Escherichia coli and differs from EC 1.1.1.25, in that it can use
CC       both quinate and shikimate as substrate and either NAD(+) or NADP(+)
CC       as acceptor.
DR   A7ZMF7, YDIB_ECO24 ;  B7US31, YDIB_ECO27 ;  B7MAQ2, YDIB_ECO45 ;
DR   B7L5P4, YDIB_ECO55 ;  Q8X5Y4, YDIB_ECO57 ;  B5YPX9, YDIB_ECO5E ;
DR   B7NTU4, YDIB_ECO7I ;  B7MVG8, YDIB_ECO81 ;  B7M0P8, YDIB_ECO8A ;
DR   C4ZYF4, YDIB_ECOBW ;  B1XG00, YDIB_ECODH ;  A8A0N8, YDIB_ECOHS ;
DR   A1ABM9, YDIB_ECOK1 ;  Q0THD7, YDIB_ECOL5 ;  P0A6D6, YDIB_ECOL6 ;
DR   B1IQ64, YDIB_ECOLC ;  P0A6D5, YDIB_ECOLI ;  B7N528, YDIB_ECOLU ;
DR   B6IBD2, YDIB_ECOSE ;  B1LE44, YDIB_ECOSM ;  Q1RBA4, YDIB_ECOUT ;
DR   B5F7D6, YDIB_SALA4 ;  Q57PS7, YDIB_SALCH ;  B5FJ81, YDIB_SALDC ;
DR   B5QVU2, YDIB_SALEP ;  B5RAU7, YDIB_SALG2 ;  B4TGJ7, YDIB_SALHS ;
DR   B4T4Q4, YDIB_SALNS ;  A9N158, YDIB_SALPB ;  B4TUS3, YDIB_SALSV ;
DR   Q8ZPR4, YDIB_SALTY ;  B2U2J6, YDIB_SHIB3 ;  P0C2L9, YDIB_SHIBS ;
DR   Q32GE1, YDIB_SHIDS ;  Q0T479, YDIB_SHIF8 ;  Q83RA2, YDIB_SHIFL ;
DR   Q3Z246, YDIB_SHISS ;
//
ID   1.1.1.283
DE   Methylglyoxal reductase (NADPH-dependent).
AN   Lactaldehyde dehydrogenase (NADP(+)).
CA   Lactaldehyde + NADP(+) = methylglyoxal + NADPH.
CC   -!- The enzyme from the yeast Saccharomyces cerevisiae catalyzes the
CC       conversion of methylglyoxal into lactaldehyde; the reverse reaction
CC       has not been demonstrated.
CC   -!- It differs in coenzyme requirement from EC 1.1.1.78, which is found
CC       in mammals.
CC   -!- It also acts on phenylglyoxal and glyoxal.
DR   Q12068, GRE2_YEAST ;  O32210, GR_BACSU   ;
//
ID   1.1.1.284
DE   S-(hydroxymethyl)glutathione dehydrogenase.
AN   ADH3.
AN   Chi-ADH.
AN   Class III alcohol dehydrogenase.
AN   FDH.
AN   Formaldehyde dehydrogenase.
AN   Formaldehyde dehydrogenase (glutathione).
AN   Formic dehydrogenase.
AN   GD-FALDH.
AN   Glutathione-dependent formaldehyde dehydrogenase.
AN   GS-FDH.
AN   NAD- and glutathione-dependent formaldehyde dehydrogenase.
AN   NAD-dependent formaldehyde dehydrogenase.
AN   NAD-linked formaldehyde dehydrogenase.
CA   S-(hydroxymethyl)glutathione + NAD(P)(+) = S-formylglutathione + NAD(P)H.
CC   -!- The substrate, S-(hydroxymethyl)glutathione, forms spontaneously from
CC       glutathione and formaldehyde; its rate of formation is increased in
CC       some bacteria by the presence of EC 4.4.1.22.
CC   -!- Forms part of the pathway that detoxifies formaldehyde, since the
CC       product is hydrolyzed by EC 3.1.2.12.
CC   -!- Also specifically reduces S-nitrosylglutathione.
CC   -!- Formerly EC 1.2.1.1.
PR   PROSITE; PDOC00058;
DR   P81600, ADHH_GADMO ;  P72324, ADHI_RHOS4 ;  P81601, ADHL_GADMO ;
DR   Q96533, ADHX_ARATH ;  Q3ZC42, ADHX_BOVIN ;  Q17335, ADHX_CAEEL ;
DR   Q54TC2, ADHX_DICDI ;  P46415, ADHX_DROME ;  P19854, ADHX_HORSE ;
DR   P11766, ADHX_HUMAN ;  P93629, ADHX_MAIZE ;  P28474, ADHX_MOUSE ;
DR   P80360, ADHX_MYXGL ;  P81431, ADHX_OCTVU ;  A2XAZ3, ADHX_ORYSI ;
DR   Q0DWH1, ADHX_ORYSJ ;  P80572, ADHX_PEA   ;  O19053, ADHX_RABIT ;
DR   P12711, ADHX_RAT   ;  P86884, ADHX_SCYCA ;  P79896, ADHX_SPAAU ;
DR   P80467, ADHX_UROHA ;  P78870, FADH1_SCHPO;  O74540, FADH2_SCHPO;
DR   P0CL53, FADH_ASPOR ;  Q06099, FADH_CANMA ;  P47734, FADH_METMR ;
DR   P45382, FADH_PARDE ;  O74685, FADH_PICPA ;  P32771, FADH_YEAST ;
DR   A7ZIA4, FRMA_ECO24 ;  Q8X5J4, FRMA_ECO57 ;  A7ZX04, FRMA_ECOHS ;
DR   A1A835, FRMA_ECOK1 ;  Q0TKS7, FRMA_ECOL5 ;  Q8FKG1, FRMA_ECOL6 ;
DR   B1J085, FRMA_ECOLC ;  P25437, FRMA_ECOLI ;  B1LIP1, FRMA_ECOSM ;
DR   Q1RFI7, FRMA_ECOUT ;  P44557, FRMA_HAEIN ;  P39450, FRMA_PASPI ;
DR   Q3Z550, FRMA_SHISS ;  P73138, FRMA_SYNY3 ;
//
ID   1.1.1.285
DE   3''-deamino-3''-oxonicotianamine reductase.
CA   2'-deoxymugineic acid + NAD(P)(+) = 3''-deamino-3''-oxonicotianamine +
CA   NAD(P)H.
//
ID   1.1.1.286
DE   Isocitrate--homoisocitrate dehydrogenase.
AN   Homoisocitrate--isocitrate dehydrogenase.
CA   (1) Isocitrate + NAD(+) = 2-oxoglutarate + CO(2) + NADH.
CA   (2) (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD(+) = 2-oxoadipate
CA   + CO(2) + NADH.
CF   Manganese; Potassium or NH(4)(+).
CC   -!- Unlike EC 1.1.1.41 and EC 1.1.1.87, this enzyme, from Pyrococcus
CC       horikoshii, can use both isocitrate and homoisocitrate as substrate.
CC   -!- May play a role in both the lysine and glutamate biosynthesis
CC       pathways.
PR   PROSITE; PDOC00389;
//
ID   1.1.1.287
DE   D-arabinitol dehydrogenase (NADP(+)).
AN   D-arabinitol dehydrogenase 1.
AN   NADP(+)-dependent D-arabinitol dehydrogenase.
CA   (1) D-arabinitol + NADP(+) = D-xylulose + NADPH.
CA   (2) D-arabinitol + NADP(+) = D-ribulose + NADPH.
CC   -!- The enzyme from the rust fungus Uromyces fabae can use D-arabinitol
CC       and D-mannitol as substrates in the forward direction and D-xylulose,
CC       D-ribulose and, to a lesser extent, D-fructose as substrates in the
CC       reverse direction.
CC   -!- This enzyme carries out the reactions of both EC 1.1.1.11 and
CC       EC 1.1.1.250, but unlike them, uses NADP(+) rather than NAD(+) as
CC       cofactor.
CC   -!- D-arabinitol is capable of quenching reactive oxygen species involved
CC       in defense reactions of the host plant.
PR   PROSITE; PDOC00058;
//
ID   1.1.1.288
DE   Xanthoxin dehydrogenase.
AN   Xanthoxin oxidase.
CA   Xanthoxin + NAD(+) = abscisic aldehyde + NADH.
CF   Molybdenum.
CC   -!- NADP(+) cannot replace NAD(+) and short-chain alcohols such as
CC       ethanol, isopropanol, butanol and cyclohexanol cannot replace
CC       xanthoxin as substrate.
CC   -!- Involved in the abscisic-acid biosynthesis pathway in plants, along
CC       with EC 1.2.3.14, EC 1.13.11.51 and EC 1.14.13.93.
DR   Q9C826, ABA2_ARATH ;
//
ID   1.1.1.289
DE   Sorbose reductase.
CA   D-glucitol + NADP(+) = L-sorbose + NADPH.
CC   -!- The reaction occurs predominantly in the reverse direction.
CC   -!- This enzyme can also convert D-fructose into D-mannitol, but more
CC       slowly.
PR   PROSITE; PDOC00060;
DR   P87219, SOU1_CANAL ;  Q9Y6Z9, SOU1_SCHPO ;
//
ID   1.1.1.290
DE   4-phosphoerythronate dehydrogenase.
AN   4-O-phosphoerythronate dehydrogenase.
AN   4PE dehydrogenase.
AN   Erythronate-4-phosphate dehydrogenase.
CA   4-phospho-D-erythronate + NAD(+) = (3R)-3-hydroxy-2-oxo-4-
CA   phosphonooxybutanoate + NADH.
CC   -!- This enzyme catalyzes the second step in the biosynthesis of the
CC       coenzyme pyridoxal 5'-phosphate in Escherichia coli.
CC   -!- The reaction occurs predominantly in the reverse direction.
CC   -!- Other enzymes involved in this pathway are EC 1.2.1.72, EC 2.6.1.52,
CC       EC 1.1.1.262, EC 2.6.99.2 and EC 1.4.3.5.
PR   PROSITE; PDOC00063;
DR   Q6F943, PDXB_ACIAD ;  B7GY62, PDXB_ACIB3 ;  B7I5Z2, PDXB_ACIB5 ;
DR   B2HX89, PDXB_ACIBC ;  B0VT23, PDXB_ACIBS ;  A3M810, PDXB_ACIBT ;
DR   B0VDM7, PDXB_ACIBY ;  A0KLP0, PDXB_AERHH ;  A4SNU1, PDXB_AERS4 ;
DR   Q0VQC3, PDXB_ALCBS ;  B6EIW3, PDXB_ALISL ;  C1DM66, PDXB_AZOVD ;
DR   Q5LIR8, PDXB_BACFN ;  Q64ZV5, PDXB_BACFR ;  Q8A2E4, PDXB_BACTN ;
DR   Q1LTA7, PDXB_BAUCH ;  Q7VRU9, PDXB_BLOFL ;  Q492H2, PDXB_BLOPB ;
DR   B3PK14, PDXB_CELJU ;  Q1QXV7, PDXB_CHRSD ;  A8ADQ9, PDXB_CITK8 ;
DR   Q47XK1, PDXB_COLP3 ;  A9KEY5, PDXB_COXBN ;  A9NAQ7, PDXB_COXBR ;
DR   Q83AR8, PDXB_COXBU ;  A7ZPD6, PDXB_ECO24 ;  B7UFX8, PDXB_ECO27 ;
DR   B7MG84, PDXB_ECO45 ;  B7LBH4, PDXB_ECO55 ;  Q8XCR0, PDXB_ECO57 ;
DR   B5YXW1, PDXB_ECO5E ;  B7NP01, PDXB_ECO7I ;  B7MXZ7, PDXB_ECO81 ;
DR   B7M6K1, PDXB_ECO8A ;  C4ZVL3, PDXB_ECOBW ;  B1X931, PDXB_ECODH ;
DR   A8A2I9, PDXB_ECOHS ;  A1ADG9, PDXB_ECOK1 ;  Q0TFC6, PDXB_ECOL5 ;
DR   Q8FFH2, PDXB_ECOL6 ;  B1IXM2, PDXB_ECOLC ;  P05459, PDXB_ECOLI ;
DR   B7N5T2, PDXB_ECOLU ;  B6I4U8, PDXB_ECOSE ;  B1LLS6, PDXB_ECOSM ;
DR   Q1R992, PDXB_ECOUT ;  C5B8N0, PDXB_EDWI9 ;  A4WCV4, PDXB_ENT38 ;
DR   A7MH63, PDXB_ENTS8 ;  Q6D2N5, PDXB_ERWCT ;  B7LLF0, PDXB_ESCF3 ;
DR   Q2SJQ9, PDXB_HAHCH ;  Q5QUE2, PDXB_IDILO ;  B5XNR7, PDXB_KLEP3 ;
DR   Q5X6I6, PDXB_LEGPA ;  Q5ZX15, PDXB_LEGPH ;  Q5WXZ0, PDXB_LEGPL ;
DR   A1U1I8, PDXB_MARAV ;  A6VXM3, PDXB_MARMS ;  C6DA76, PDXB_PECCP ;
DR   Q7N2B2, PDXB_PHOLL ;  Q6LNU2, PDXB_PHOPR ;  Q7MV70, PDXB_PORGI ;
DR   B4EZF9, PDXB_PROMH ;  Q48KQ3, PDXB_PSE14 ;  Q15QG8, PDXB_PSEA6 ;
DR   A6V8H9, PDXB_PSEA7 ;  B7UVK4, PDXB_PSEA8 ;  Q02JM2, PDXB_PSEAB ;
DR   Q9I3W9, PDXB_PSEAE ;  Q1I7B3, PDXB_PSEE4 ;  Q4KFD1, PDXB_PSEF5 ;
DR   C3K5G7, PDXB_PSEFS ;  Q3IF36, PDXB_PSEHT ;  A4XTK4, PDXB_PSEMY ;
DR   A5W6I8, PDXB_PSEP1 ;  Q3K9D1, PDXB_PSEPF ;  B0KGD9, PDXB_PSEPG ;
DR   Q88L20, PDXB_PSEPK ;  B1J5D7, PDXB_PSEPW ;  Q884R9, PDXB_PSESM ;
DR   Q4ZVE7, PDXB_PSEU2 ;  A4VKJ1, PDXB_PSEU5 ;  Q4FV16, PDXB_PSYA2 ;
DR   Q1QE21, PDXB_PSYCK ;  A1SW94, PDXB_PSYIN ;  A5WHK7, PDXB_PSYWF ;
DR   A1AWW7, PDXB_RUTMC ;  Q21LK8, PDXB_SACD2 ;  B5EZQ4, PDXB_SALA4 ;
DR   A9MJ55, PDXB_SALAR ;  Q57LY4, PDXB_SALCH ;  B5FPL4, PDXB_SALDC ;
DR   B5R3Q1, PDXB_SALEP ;  B5RCJ5, PDXB_SALG2 ;  B4TBN9, PDXB_SALHS ;
DR   B4SZP2, PDXB_SALNS ;  Q5PCV8, PDXB_SALPA ;  A9N474, PDXB_SALPB ;
DR   C0PZZ3, PDXB_SALPC ;  B5BCH6, PDXB_SALPK ;  Q2S0U3, PDXB_SALRD ;
DR   B4TQA6, PDXB_SALSV ;  P60801, PDXB_SALTI ;  P60802, PDXB_SALTY ;
DR   A8GH44, PDXB_SERP5 ;  A1S7K2, PDXB_SHEAM ;  B8EEB4, PDXB_SHEB2 ;
DR   A3D669, PDXB_SHEB5 ;  A6WQ07, PDXB_SHEB8 ;  A9KTV0, PDXB_SHEB9 ;
DR   Q12P58, PDXB_SHEDO ;  Q084S1, PDXB_SHEFN ;  B0TKZ7, PDXB_SHEHH ;
DR   A3QFC7, PDXB_SHELP ;  Q8ECR2, PDXB_SHEON ;  A4Y882, PDXB_SHEPC ;
DR   A0KV91, PDXB_SHESA ;  A8FTT7, PDXB_SHESH ;  Q0HKB6, PDXB_SHESM ;
DR   Q56731, PDXB_SHESP ;  Q0HWL8, PDXB_SHESR ;  A1RIA7, PDXB_SHESW ;
DR   Q56733, PDXB_SHEVD ;  B1KKP1, PDXB_SHEWM ;  B2TWA2, PDXB_SHIB3 ;
DR   Q31YD8, PDXB_SHIBS ;  Q32DL6, PDXB_SHIDS ;  Q0T2G5, PDXB_SHIF8 ;
DR   Q83QR1, PDXB_SHIFL ;  Q3YZP1, PDXB_SHISS ;  Q2NSH9, PDXB_SODGM ;
DR   C5BR49, PDXB_TERTT ;  Q31IH6, PDXB_THICR ;  C4LF16, PDXB_TOLAT ;
DR   A5CWD1, PDXB_VESOH ;  Q9KQ92, PDXB_VIBCH ;  Q5E452, PDXB_VIBF1 ;
DR   B5FFP0, PDXB_VIBFM ;  Q87MN8, PDXB_VIBPA ;  B7VL81, PDXB_VIBSL ;
DR   Q8DB36, PDXB_VIBVU ;  Q7MIT6, PDXB_VIBVY ;  Q8D2P6, PDXB_WIGBR ;
DR   A1JL55, PDXB_YERE8 ;  A7FGL9, PDXB_YERP3 ;  Q1C676, PDXB_YERPA ;
DR   B2K8H7, PDXB_YERPB ;  Q8D0U3, PDXB_YERPE ;  A9R7V0, PDXB_YERPG ;
DR   Q1CHL8, PDXB_YERPN ;  A4TM66, PDXB_YERPP ;  Q668W7, PDXB_YERPS ;
DR   B1JGI0, PDXB_YERPY ;
//
ID   1.1.1.291
DE   2-hydroxymethylglutarate dehydrogenase.
CA   (S)-2-hydroxymethylglutarate + NAD(+) = 2-formylglutarate + NADH.
CC   -!- NADP(+) cannot replace NAD(+).
CC   -!- Forms part of the nicotinate-fermentation catabolism pathway in
CC       Eubacterium barkeri.
CC   -!- Other enzymes involved in this pathway are EC 1.17.1.5, EC 1.3.7.1,
CC       EC 3.5.2.18, EC 5.4.99.4, EC 5.3.3.6, EC 4.2.1.85 and EC 4.1.3.32.
PR   PROSITE; PDOC00697;
DR   Q0QLF5, HMGD_EUBBA ;
//
ID   1.1.1.292
DE   1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming).
AN   1,5-anhydro-D-fructose reductase.
AN   AFR.
CA   1,5-anhydro-D-mannitol + NADP(+) = 1,5-anhydro-D-fructose + NADPH.
CC   -!- Present in some but not all Rhizobium species.
CC   -!- Differs from hepatic 1,5-anhydro-D-fructose reductase, which yields
CC       1,5-anhydro-D-glucitol as the product (see EC 1.1.1.263).
CC   -!- In Sinorhizobium morelense, the product of the reaction, 1,5-anhydro-
CC       D-mannitol, can be further metabolized to D-mannose.
CC   -!- Also reduces 1,5-anhydro-D-erythro-hexo-2,3-diulose and 2-ketoaldoses
CC       (called osones), such as D-glucosone (D-arabino-hexos-2-ulose) and
CC       6-deoxy-D-glucosone.
CC   -!- Does not reduce common aldoses and ketoses, or non-sugar aldehydes
CC       and ketones.
DR   Q2I8V6, AFR_ENSAD  ;  Q92KZ3, AFR_RHIME  ;
//
ID   1.1.1.293
DE   Deleted entry.
//
ID   1.1.1.294
DE   Chlorophyll(ide) b reductase.
AN   Chl b reductase.
AN   Chlorophyll b reductase.
CA   7(1)-hydroxychlorophyllide a + NAD(P)(+) = chlorophyllide b + NAD(P)H.
CC   -!- Carries out the first step in the conversion of chlorophyll b to
CC       chlorophyll a.
CC   -!- Involved in chlorophyll degradation, which occurs during leaf
CC       senescence and it also forms part of the chlorophyll cycle, which
CC       interconverts chlorophyll a and b in response to changing light
CC       conditions.
CC   -!- While both chlorophyll a and chlorophyll b are found in higher
CC       plants, only breakdown products derived from chlorophyll a are found
CC       in the end products, i.e. non-fluorescent chlorophyll catabolites
CC       (NCCs).
CC   -!- The transition from chlorophyll b, which contains a formyl group on
CC       C7, to chlorophyll a, which contains a methyl group on C7, proceeds
CC       through the intermediate 7(1)-hydroxychlorophyll.
CC   -!- Another enzyme, which requires ferredoxin but has not been
CC       characterized fully, is required to complete the conversion.
PR   PROSITE; PDOC00060;
DR   Q8LEU3, NOL_ARATH  ;  Q84ST4, NOL_ORYSJ  ;  Q93ZA0, NYC1_ARATH ;
DR   Q5N800, NYC1_ORYSJ ;
//
ID   1.1.1.295
DE   Momilactone-A synthase.
AN   Momilactone A synthase.
CA   3-beta-hydroxy-9-beta-pimara-7,15-diene-19,6-beta-olide + NAD(P)(+) =
CA   momilactone A + NAD(P)H.
CC   -!- The rice phytoalexin momilactone A is a diterpenoid secondary
CC       metabolite that is involved in the defense mechanism of the plant.
CC   -!- Momilactone A is produced in response to attack by a pathogen through
CC       the perception of elicitor signal molecules such as chitin
CC       oligosaccharide, or after exposure to UV irradiation.
CC   -!- The enzyme, which catalyzes the last step in the biosynthesis of
CC       momilactone A, can use both NAD(+) and NADP(+) but activity is higher
CC       with NAD(+).
PR   PROSITE; PDOC00060;
DR   Q7FAE1, MOMAS_ORYSJ;
//
ID   1.1.1.296
DE   Dihydrocarveol dehydrogenase.
AN   Carveol dehydrogenase.
CA   Menth-8-en-2-ol + NAD(+) = menth-8-en-2-one + NADH.
CC   -!- This enzyme from the Gram-positive bacterium Rhodococcus erythropolis
CC       DCL14 forms part of the carveol and dihydrocarveol degradation
CC       pathway.
CC   -!- Accepts all eight stereoisomers of menth-8-en-2-ol as substrate,
CC       although some isomers are converted faster than others.
CC   -!- The preferred substrates are (+)-neoisodihydrocarveol, (+)-
CC       isodihydrocarveol, (+)-dihydrocarveol and (-)-isodihydrocarveol.
//
ID   1.1.1.297
DE   Limonene-1,2-diol dehydrogenase.
CA   Menth-8-ene-1,2-diol + NAD(+) = 1-hydroxymenth-8-en-2-one + NADH.
CC   -!- While the enzyme from the Gram-positive bacterium Rhodococcus
CC       erythropolis DCL14 can use both (1S,2S,4R)- and (1R,2R,4S)-menth-8-
CC       ene-1,2-diol as substrate, activity is higher with (1S,2S,4R)-menth-
CC       8-ene-1,2-diol as substrate.
//
ID   1.1.1.298
DE   3-hydroxypropionate dehydrogenase (NADP(+)).
CA   3-hydroxypropanoate + NADP(+) = 3-oxopropanoate + NADPH.
CC   -!- Catalyzes the reduction of 3-oxopropanoate to 3-hydroxypropanoate,
CC       a key step in the 3-hydroxypropanoate and the
CC       3-hydroxypropanoate/4-hydroxybutyrate cycles, autotrophic CO(2)
CC       fixation pathways found in some green non-sulfur phototrophic
CC       bacteria and archaea, respectively.
CC   -!- The enzyme from Chloroflexus aurantiacus is bifunctional, and also
CC       catalyzes the upstream reaction in the pathway, EC 1.2.1.75.
CC   -!- Different from EC 1.1.1.59 by cofactor preference.
DR   A7ZKB3, RUTE_ECO24 ;  B7UNZ1, RUTE_ECO27 ;  B7MIF5, RUTE_ECO45 ;
DR   B7LFB8, RUTE_ECO55 ;  Q8XAU9, RUTE_ECO57 ;  B5YU50, RUTE_ECO5E ;
DR   B7NLB8, RUTE_ECO7I ;  B7MTF1, RUTE_ECO81 ;  B7M8Z3, RUTE_ECO8A ;
DR   C4ZQD6, RUTE_ECOBW ;  B1X9C9, RUTE_ECODH ;  A7ZYW3, RUTE_ECOHS ;
DR   A1A9R3, RUTE_ECOK1 ;  Q0TJ59, RUTE_ECOL5 ;  Q8FJ44, RUTE_ECOL6 ;
DR   B1IV89, RUTE_ECOLC ;  P75894, RUTE_ECOLI ;  B7N3G4, RUTE_ECOLU ;
DR   B6I984, RUTE_ECOSE ;  B1LIZ7, RUTE_ECOSM ;  Q1RDK9, RUTE_ECOUT ;
DR   A4W921, RUTE_ENT38 ;  A7MFX7, RUTE_ENTS8 ;  B5XXN4, RUTE_KLEP3 ;
DR   A6T798, RUTE_KLEP7 ;  Q32HQ3, RUTE_SHIDS ;  Q0T626, RUTE_SHIF8 ;
DR   Q83RV4, RUTE_SHIFL ;  Q3Z3A5, RUTE_SHISS ;  A1JMW8, RUTE_YERE8 ;
DR   P39831, YDFG_ECOLI ;
//
ID   1.1.1.299
DE   Malate dehydrogenase (NAD(P)(+)).
CA   (S)-malate + NAD(P)(+) = oxaloacetate + NAD(P)H.
CC   -!- This enzyme, which was characterized from the methanogenic archaeon
CC       Methanobacterium thermoautotrophicum, catalyzes only the reduction of
CC       oxaloacetate, and can use NAD(+) and NADP(+) with similar specific
CC       activity.
CC   -!- Different from EC 1.1.1.37, EC 1.1.1.82 and EC 1.1.5.4.
//
ID   1.1.1.300
DE   NADP-retinol dehydrogenase.
AN   All-trans retinal reductase.
AN   All-trans-retinol dehydrogenase.
AN   NADP(H)-dependent retinol dehydrogenase/reductase.
AN   Retinol dehydrogenase (NADP(+)).
CA   All-trans-retinol + NADP(+) = all-trans-retinal + NADPH.
CC   -!- Greater catalytic efficiency in the reductive direction.
CC   -!- This observation, and the enzyme's localization at the entrance to
CC       the mitochondrial matrix, suggest that it may function to protect
CC       mitochondria against oxidative stress associated with the highly
CC       reactive retinal produced from dietary beta-carotene by
CC       EC 1.14.99.36.
CC   -!- Km-values for NADP(+) and NADPH are at least 800-fold lower than
CC       those for NAD(+) and NADH.
CC   -!- This enzyme differs from EC 1.1.1.105 which prefers NAD(+) and NADH.
CC   -!- Formerly EC 1.1.1.n2.
PR   PROSITE; PDOC00060;
DR   O77769, DHRS3_BOVIN;  O75911, DHRS3_HUMAN;  O88876, DHRS3_MOUSE;
DR   A1L1W4, RD10A_DANRE;  Q6DCT3, RD10A_XENLA;  Q7T2D1, RD10B_DANRE;
DR   Q6NRV4, RD10B_XENLA;  Q8HZT6, RDH10_BOVIN;  Q8IZV5, RDH10_HUMAN;
DR   Q8VCH7, RDH10_MOUSE;  Q80ZF7, RDH10_RAT  ;  Q5XGF7, RDH10_XENTR;
DR   Q8TC12, RDH11_HUMAN;  Q9QYF1, RDH11_MOUSE;  Q9N126, RDH8_BOVIN ;
DR   Q9NYR8, RDH8_HUMAN ;
//
ID   1.1.1.301
DE   D-arabitol-phosphate dehydrogenase.
AN   APDH.
AN   D-arabitol 1-phosphate dehydrogenase.
AN   D-arabitol 5-phosphate dehydrogenase.
CA   D-arabinitol 1-phosphate + NAD(+) = D-xylulose 5-phosphate + NADH.
CC   -!- This enzyme participates in arabitol catabolism.
CC   -!- The enzyme also converts D-arabitol 5-phosphate to D-ribulose
CC       5-phosphate at a lower rate.
CC   -!- Formerly EC 1.1.1.n10.
PR   PROSITE; PDOC00058;
//
ID   1.1.1.302
DE   2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase.
AN   2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase.
CA   2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one + NAD(P)(+) =
CA   2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + NAD(P)H.
CC   -!- The reaction proceeds in the opposite direction.
CC   -!- A step in riboflavin biosynthesis, NADPH and NADH function equally
CC       well as reductant.
CC   -!- Differs from EC 1.1.1.193 since it does not catalyze the reduction of
CC       5-amino-6-ribosylaminopyrimidine-2,4(1H,3H)-dione 5'-phosphate.
//
ID   1.1.1.303
DE   Diacetyl reductase ((R)-acetoin forming).
AN   (R)-acetoin dehydrogenase.
CA   (R)-acetoin + NAD(+) = diacetyl + NADH.
CC   -!- The reaction is catalyzed in the reverse direction.
CC   -!- This activity is usually associated with butanediol dehydrogenase
CC       activity (EC 1.1.1.4 or EC 1.1.1.76).
CC   -!- While the butanediol dehydrogenase activity is reversible, diacetyl
CC       reductase activity is irreversible.
CC   -!- This enzyme has been reported in the yeast Saccharomyces cerevisiae.
CC   -!- Different from EC 1.1.1.304.
CC   -!- Formerly EC 1.1.1.5.
PR   PROSITE; PDOC00058;
DR   P39714, BDH1_YEAST ;  P39713, BDH2_YEAST ;
//
ID   1.1.1.304
DE   Diacetyl reductase ((S)-acetoin forming).
AN   (S)-acetoin dehydrogenase.
CA   (S)-acetoin + NAD(+) = diacetyl + NADH.
CC   -!- The reaction is catalyzed in the reverse direction.
CC   -!- This activity is usually associated with butanediol dehydrogenase
CC       activity (EC 1.1.1.4 or EC 1.1.1.76).
CC   -!- While the butanediol dehydrogenase activity is reversible, diacetyl
CC       reductase activity is irreversible.
CC   -!- This enzyme has been reported in the bacteria Geobacillus
CC       stearothermophilus, Enterobacter aerogenes and Klebsiella pneumoniae.
CC   -!- Different from EC 1.1.1.303.
CC   -!- Formerly EC 1.1.1.5.
PR   PROSITE; PDOC00060;
DR   Q48436, BUDC_KLEPN ;  Q04520, BUDC_RAOTE ;  Q5HJP2, BUTA_STAAC ;
DR   P66775, BUTA_STAAM ;  P99120, BUTA_STAAN ;  Q6GKH9, BUTA_STAAR ;
DR   Q6GCZ8, BUTA_STAAS ;  P66776, BUTA_STAAW ;  Q5HKG6, BUTA_STAEQ ;
DR   Q8CQD2, BUTA_STAES ;
//
ID   1.1.1.305
DE   UDP-glucuronic acid oxidase (UDP-4-keto-hexauronic acid decarboxylating).
AN   ArnADH.
AN   UDP-GlcUA decarboxylase.
CA   UDP-alpha-D-glucuronate + NAD(+) = UDP-beta-L-threo-pentapyranos-4-ulose
CA   + CO(2) + NADH.
CC   -!- The activity is part of a bifunctional enzyme also performing the
CC       reaction of EC 2.1.2.13.
CC   -!- Formerly EC 1.1.1.n1.
DR   A0KGY6, ARNA_AERHH ;  A4SQW9, ARNA_AERS4 ;  A7ZP73, ARNA_ECO24 ;
DR   B7UFR7, ARNA_ECO27 ;  B7MG22, ARNA_ECO45 ;  B7LAS0, ARNA_ECO55 ;
DR   Q8XDZ3, ARNA_ECO57 ;  B5YXP8, ARNA_ECO5E ;  B7NNT4, ARNA_ECO7I ;
DR   B7MXT6, ARNA_ECO81 ;  B7M5T7, ARNA_ECO8A ;  C4ZU97, ARNA_ECOBW ;
DR   B1X8W8, ARNA_ECODH ;  A8A2C2, ARNA_ECOHS ;  A1ADA7, ARNA_ECOK1 ;
DR   Q0TFI7, ARNA_ECOL5 ;  Q8FFM1, ARNA_ECOL6 ;  B1IXT2, ARNA_ECOLC ;
DR   P77398, ARNA_ECOLI ;  B7N5M0, ARNA_ECOLU ;  B6I7J8, ARNA_ECOSE ;
DR   B1LLK9, ARNA_ECOSM ;  Q1R9G0, ARNA_ECOUT ;  A4WAM3, ARNA_ENT38 ;
DR   Q6D2F1, ARNA_ERWCT ;  B2VBI9, ARNA_ERWT9 ;  B7LM76, ARNA_ESCF3 ;
DR   B5XTK9, ARNA_KLEP3 ;  A6TF98, ARNA_KLEP7 ;  C6DAW5, ARNA_PECCP ;
DR   Q7N3Q7, ARNA_PHOLL ;  B4ETL7, ARNA_PROMH ;  Q48HZ1, ARNA_PSE14 ;
DR   A6V1P0, ARNA_PSEA7 ;  B7VBN2, ARNA_PSEA8 ;  Q02R25, ARNA_PSEAB ;
DR   Q9HY63, ARNA_PSEAE ;  Q4KC82, ARNA_PSEF5 ;  C3KAD2, ARNA_PSEFS ;
DR   Q3KCC1, ARNA_PSEPF ;  Q4ZSZ2, ARNA_PSEU2 ;  B5EZH8, ARNA_SALA4 ;
DR   P0C0R6, ARNA_SALCH ;  B5FNT9, ARNA_SALDC ;  B5R272, ARNA_SALEP ;
DR   B5RCC4, ARNA_SALG2 ;  B4TBG6, ARNA_SALHS ;  B4SYX1, ARNA_SALNS ;
DR   Q5PNA6, ARNA_SALPA ;  A9N5B2, ARNA_SALPB ;  C0Q069, ARNA_SALPC ;
DR   B5BCP6, ARNA_SALPK ;  B4TPI2, ARNA_SALSV ;  Q8Z540, ARNA_SALTI ;
DR   O52325, ARNA_SALTY ;  A8GDR7, ARNA_SERP5 ;  A8FRR2, ARNA_SHESH ;
DR   B2TW38, ARNA_SHIB3 ;  Q31YK2, ARNA_SHIBS ;  Q32DT3, ARNA_SHIDS ;
DR   Q0T2M8, ARNA_SHIF8 ;  Q83QT8, ARNA_SHIFL ;  Q3YZV1, ARNA_SHISS ;
DR   Q2NRV7, ARNA_SODGM ;  Q8D341, ARNA_WIGBR ;  A1JPN5, ARNA_YERE8 ;
DR   A7FHH4, ARNA_YERP3 ;  Q1C742, ARNA_YERPA ;  B2K5L3, ARNA_YERPB ;
DR   Q8ZDX8, ARNA_YERPE ;  A9R093, ARNA_YERPG ;  Q1CIH7, ARNA_YERPN ;
DR   A4TIM4, ARNA_YERPP ;  Q93PD8, ARNA_YERPS ;  B1JJ30, ARNA_YERPY ;
//
ID   1.1.1.306
DE   S-(hydroxymethyl)mycothiol dehydrogenase.
AN   Mycothiol-dependent formaldehyde dehydrogenase.
AN   NAD/factor-dependent formaldehyde dehydrogenase.
CA   S-(hydroxymethyl)mycothiol + NAD(+) = S-formylmycothiol + NADH.
CF   Zinc.
CC   -!- S-hydroxymethylmycothiol is believed to form spontaneously from
CC       formaldehyde and mycothiol.
CC   -!- This enzyme oxidizes the product of this spontaneous reaction to
CC       S-formylmycothiol, in a reaction that is analogous to EC 1.1.1.284,
CC       S-(hydroxymethyl)glutathione dehydrogenase.
CC   -!- Formerly EC 1.2.1.66.
PR   PROSITE; PDOC00058;
DR   P80094, FADH_AMYME ;
//
ID   1.1.1.307
DE   D-xylose reductase.
CA   Xylitol + NAD(P)(+) = D-xylose + NAD(P)H.
CC   -!- Xylose reductase catalyzes the initial reaction in the xylose
CC       utilization pathway, the NAD(P)H dependent reduction of xylose to
CC       xylitol.
//
ID   1.1.1.308
DE   Sulfopropanediol 3-dehydrogenase.
AN   Dihydroxypropanesulfonate 3-dehydrogenase.
CA   (R)-2,3-dihydroxypropane-1-sulfonate + 2 NAD(+) + H(2)O = (R)-3-
CA   sulfolactate + 2 NADH.
CC   -!- The enzyme is involved in degradation of (R)-2,3-
CC       dihydroxypropanesulfonate.
//
ID   1.1.1.309
DE   Phosphonoacetaldehyde reductase (NADH).
CA   2-hydroxyethylphosphonate + NAD(+) = phosphonoacetaldehyde + NADH.
CC   -!- The enzyme from Streptomyces viridochromogenes catalyzes a step in
CC       the biosynthesis of phosphinothricin tripeptide, the reduction of
CC       phosphonoacetaldehyde to 2-hydroxyethylphosphonate.
CC   -!- The preferred cofactor is NADH, lower activity with NADPH.
//
ID   1.1.1.310
DE   (S)-sulfolactate dehydrogenase.
AN   (2S)-3-sulfolactate dehydrogenase.
CA   (2S)-3-sulfolactate + NAD(+) = 3-sulfopyruvate + NADH.
CC   -!- This enzyme, isolated from the bacterium Chromohalobacter salexigens
CC       DSM 3043, acts only on the (S)-enantiomer of 3-sulfolactate.
CC   -!- Combined with EC 1.1.1.272, it provides a racemase system that
CC       converts (2S)-3-sulfolactate to (2R)-3-sulfolactate, which is
CC       degraded further by EC 4.4.1.24.
CC   -!- Specific for NAD(+).
PR   PROSITE; PDOC00063;
//
ID   1.1.1.311
DE   (S)-1-phenylethanol dehydrogenase.
AN   PED.
CA   (S)-1-phenylethanol + NAD(+) = acetophenone + NADH.
CC   -!- The enzyme is involved in degradation of ethylbenzene.
PR   PROSITE; PDOC00060;
//
ID   1.1.1.312
DE   2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase.
AN   4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase.
CA   4-carboxy-2-hydroxymuconate semialdehyde hemiacetal + NADP(+) = 2-oxo-
CA   2H-pyran-4,6-dicarboxylate + NADPH.
CC   -!- The enzyme does not act on unsubstituted aliphatic or aromatic
CC       aldehydes or glucose; NAD(+) can replace NADP(+), but with lower
CC       affinity.
CC   -!- The enzyme was initially believed to act on 4-carboxy-2-hydroxy-
CC       cis,cis-muconate 6-semialdehyde and produce 4-carboxy-2-hydroxy-
CC       cis,cis-muconate.
CC   -!- However, later studies showed that the substrate is the hemiacetal
CC       form, and the product is 2-oxo-2H-pyran-4,6-dicarboxylate.
CC   -!- Formerly EC 1.2.1.45.
//
ID   1.1.1.313
DE   Sulfoacetaldehyde reductase.
CA   Isethionate + NADP(+) = 2-sulfoacetaldehyde + NADPH.
CC   -!- Catalyzes the reaction only in the opposite direction.
CC   -!- Involved in taurine degradation.
CC   -!- The bacterium Chromohalobacter salexigens strain DSM 3043 possesses
CC       two enzymes that catalyze this reaction, a constitutive enzyme
CC       (encoded by isfD2) and an inducible enzyme (encoded by isfD).
CC   -!- The latter is induced by taurine, and is responsible for most of the
CC       activity observed in taurine-grown cells.
//
ID   1.1.1.314
DE   Germacrene A alcohol dehydrogenase.
CA   Germacra-1(10),4,11(13)-trien-12-ol + 2 NADP(+) + H(2)O = germacra-
CA   1(10),4,11(13)-trien-12-oate + 2 NADPH.
CC   -!- In Lactuca sativa EC 1.1.1.314 is a mutifunctional enzyme with
CC       EC 1.14.13.123.
DR   D5JBX1, GAO_BARSP  ;  D5JBW8, GAO_CICIN  ;  D5JBX0, GAO_HELAN  ;
DR   D5J9U8, GAO_LACSA  ;  D5JBW9, GAO_SAUCO  ;
//
ID   1.1.1.n1
DE   Transferred entry: 1.1.1.305.
//
ID   1.1.1.n2
DE   Transferred entry: 1.1.1.300.
//
ID   1.1.1.n3
DE   UDP-N-acetyl-D-mannosamine dehydrogenase.
AN   UDP-ManNAc 6-dehydrogenase.
CA   UDP-N-acetyl-D-mannosamine + 2 NAD(+) + H(2)O = UDP-N-acetyl-D-
CA   mannosaminuronate + 2 NADH.
CC   -!- The enzyme cannot use NADP(+) instead of NAD(+).
CC   -!- It is also found in enterobacteria.
DR   P67066, WECC_ECO57 ;  P27829, WECC_ECOLI ;  A6UU98, WECC_META3 ;
DR   Q57871, WECC_METJA ;  A4FY94, WECC_METM5 ;  A6VK13, WECC_METM7 ;
DR   Q6LZC3, WECC_METMP ;  A6USK4, WECC_METVS ;  Q8Z389, WECC_SALTI ;
DR   Q9L6R4, WECC_SALTY ;  P67067, WECC_SHIFL ;  Q8ZAE4, WECC_YERPE ;
//
ID   1.1.1.n4
DE   (-)-trans-carveol dehydrogenase.
AN   (4R,6S)-carveol dehydrogenase.
AN   Carveol dehydrogenase.
AN   CDH.
CA   (1) (-)-(4R,6S)-trans-carveol + NAD(+) = (-)-(4R)-carvone + NADH.
CA   (2) (+)-(4S,6S)-cis-carveol + NAD(+) = (+)-(4S)-carvone + NADH.
CC   -!- Catalyzes the oxidation of carveol to carvone, with a strong
CC       stereoselectivity since it efficiently converts only the (6S)-
CC       stereoisomers, of which (-)-(4R,6S)-trans-carveol is the better
CC       substrate.
CC   -!- Displays a broad substrate specificity with a preference for
CC       substituted cyclohexanols, and does not catalyze the oxidation of
CC       primary or short chain aliphatic secondary alcohols.
CC   -!- Is also able, albeit more slowly, to oxidize limonene-1,2-diol into
CC       1-hydroxy-2-oxolimonene.
DR   Q9RA05, LIMC_RHOER ;
//
ID   1.1.1.n5
DE   3-methylmalate dehydrogenase.
CA   (2R,3S)-3-methylmalate + NAD(+) = 2-oxobutanoate + CO(2) + NADH.
CF   Manganese or magnesium.
CC   -!- The enzyme from Methanocaldococcus jannaschii also catalyzes the
CC       reaction of EC 1.1.1.85 and EC 1.1.1.83.
DR   Q58130, LEU3_METJA ;
//
ID   1.1.1.n6
DE   D-chiro-inositol 3-dehydrogenase.
AN   DCI 3-dehydrogenase.
CA   D-chiro-inositol + NAD(+) = 2,3,5/4,6-pentahydroxycyclohexanone + NADH.
CC   -!- The enzyme also catalyzes the reaction of EC 1.1.1.18 and can also
CC       use D-glucose and D-xylose.
CC   -!- It shows trace activity with D-ribose and D-fructose.
CC   -!- Part of the myo-inositol/D-chiro-inositol degradation pathway leading
CC       to acetyl-CoA together EC 5.3.99.n1, EC 4.2.1.44, EC 3.7.1.n2,
CC       EC 5.3.1.n1, EC 2.7.1.92, EC 4.1.2.29 and EC 1.2.1.18.
DR   A7ZAH5, IOLG_BACA2 ;  Q9KAH1, IOLG_BACHD ;  Q65D06, IOLG_BACLD ;
DR   Q5WKY6, IOLG_BACSK ;  P26935, IOLG_BACSU ;  A5YBJ7, IOLG_LACCA ;
DR   Q88S38, IOLG_LACPL ;
//
ID   1.1.1.n7
DE   Benzil reductase.
CA   Benzoin + NADP(+) = benzil + NADPH.
DR   Q8RJB2, BZRD_BACCE ;  O32099, BZRD_BACSU ;  P40580, BZRD_YEAST ;
DR   Q8R536, SPRE_MERUN ;
//
ID   1.1.1.n8
DE   L-idonate dehydrogenase.
CA   L-idonate + NAD(+) = 5-dehydrogluconate + NADH.
CC   -!- Involved in the catabolism of ascorbic acid (vitamin C) to tartaric
CC       acid.
CC   -!- No activity observed with NADP(+).
DR   Q1PSI9, IDND_VITVI ;
//
ID   1.1.1.n9
DE   D-galacturonate reductase.
AN   GalUR.
CA   L-galactonate + NADP(+) = D-galacturonate + NADPH.
CC   -!- Involved in ascorbic acid (vitamin C) biosynthesis in plants.
//
ID   1.1.1.n10
DE   Transferred entry: 1.1.1.301.
//
ID   1.1.1.n11
DE   Succinic semialdehyde reductase.
CA   4-hydroxybutanoate + NADP(+) = succinate semialdehyde + NADPH.
DR   O43488, ARK72_HUMAN;  Q8CG76, ARK72_MOUSE;  Q8CG45, ARK72_RAT  ;
//
ID   1.1.2.1
DE   Transferred entry: 1.1.5.3.
//
ID   1.1.2.2
DE   Mannitol dehydrogenase (cytochrome).
AN   Polyol dehydrogenase.
CA   D-mannitol + ferricytochrome c = D-fructose + ferrocytochrome c.
CC   -!- Acts on polyols with a D-lyxo configuration, such as D-mannitol and
CC       D-sorbitol.
//
ID   1.1.2.3
DE   L-lactate dehydrogenase (cytochrome).
AN   Cytochrome b2.
AN   L-lactate ferricytochrome c oxidoreductase.
AN   Lactic acid dehydrogenase.
CA   (S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c +
CA   2 H(+).
CF   FMN; Protoheme IX.
PR   PROSITE; PDOC00170;
PR   PROSITE; PDOC00482;
DR   P09437, CYB2_HANAN ;  P00175, CYB2_YEAST ;  P95040, LLDD1_MYCTU;
DR   P95143, LLDD2_MYCTU;  Q6FFS1, LLDD_ACIAD ;  B7H2H0, LLDD_ACIB3 ;
DR   B7IBS4, LLDD_ACIB5 ;  B2I061, LLDD_ACIBC ;  B0VND0, LLDD_ACIBS ;
DR   A3M0X0, LLDD_ACIBT ;  B0V6L1, LLDD_ACIBY ;  A3N3E5, LLDD_ACTP2 ;
DR   B3GZA5, LLDD_ACTP7 ;  B0BTC7, LLDD_ACTPJ ;  B9K115, LLDD_AGRVS ;
DR   Q6WB83, LLDD_ALCFA ;  A8HTC9, LLDD_AZOC5 ;  Q6G4R2, LLDD_BARHE ;
DR   Q6G0J2, LLDD_BARQU ;  A9IN89, LLDD_BART1 ;  B8H3Q5, LLDD_CAUCN ;
DR   Q9A943, LLDD_CAUCR ;  B0T7X2, LLDD_CAUSK ;  Q1R0J2, LLDD_CHRSD ;
DR   A8ARJ1, LLDD_CITK8 ;  A7ZTF9, LLDD_ECO24 ;  B7ULG1, LLDD_ECO27 ;
DR   B7MFG9, LLDD_ECO45 ;  B7L725, LLDD_ECO55 ;  Q8XDF7, LLDD_ECO57 ;
DR   B5YWA7, LLDD_ECO5E ;  B7NPB4, LLDD_ECO7I ;  B7N251, LLDD_ECO81 ;
DR   B7M492, LLDD_ECO8A ;  C4ZXJ7, LLDD_ECOBW ;  B1X8M0, LLDD_ECODH ;
DR   A8A670, LLDD_ECOHS ;  A1AHE2, LLDD_ECOK1 ;  Q0TBK1, LLDD_ECOL5 ;
DR   Q8FCB1, LLDD_ECOL6 ;  B1IZI5, LLDD_ECOLC ;  P33232, LLDD_ECOLI ;
DR   B7NER0, LLDD_ECOLU ;  B6I3I4, LLDD_ECOSE ;  B1LK44, LLDD_ECOSM ;
DR   Q1R4Z0, LLDD_ECOUT ;  A4W540, LLDD_ENT38 ;  A7MNF6, LLDD_ENTS8 ;
DR   Q6DAY3, LLDD_ERWCT ;  B7LTL2, LLDD_ESCF3 ;  Q7VPI9, LLDD_HAEDU ;
DR   Q4QJK8, LLDD_HAEI8 ;  A5UBE3, LLDD_HAEIE ;  A5UFG9, LLDD_HAEIG ;
DR   P46454, LLDD_HAEIN ;  B5XMV0, LLDD_KLEP3 ;  A6TFK0, LLDD_KLEP7 ;
DR   A6VCM8, LLDD_PSEA7 ;  B7V1I3, LLDD_PSEA8 ;  Q02FQ1, LLDD_PSEAB ;
DR   Q9HV37, LLDD_PSEAE ;  Q1IF69, LLDD_PSEE4 ;  C3K053, LLDD_PSEFS ;
DR   A4XYG7, LLDD_PSEMY ;  A5W9B2, LLDD_PSEP1 ;  B0KIT4, LLDD_PSEPG ;
DR   Q88DT3, LLDD_PSEPK ;  B1J244, LLDD_PSEPW ;  Q4ZY06, LLDD_PSEU2 ;
DR   B5EXA8, LLDD_SALA4 ;  A9MLC3, LLDD_SALAR ;  Q57ID8, LLDD_SALCH ;
DR   B5FLH2, LLDD_SALDC ;  B5R5C7, LLDD_SALEP ;  B5RGI4, LLDD_SALG2 ;
DR   B4T986, LLDD_SALHS ;  B4SXA4, LLDD_SALNS ;  Q5PLQ7, LLDD_SALPA ;
DR   A9MVJ5, LLDD_SALPB ;  C0Q1T7, LLDD_SALPC ;  B5BHX7, LLDD_SALPK ;
DR   B4TZU7, LLDD_SALSV ;  Q8Z2E5, LLDD_SALTI ;  Q8ZL61, LLDD_SALTY ;
DR   A8GIL1, LLDD_SERP5 ;  B2U5C2, LLDD_SHIB3 ;  Q31V17, LLDD_SHIBS ;
DR   Q329P9, LLDD_SHIDS ;  Q0SYD1, LLDD_SHIF8 ;  Q83PP7, LLDD_SHIFL ;
DR   Q3YVX0, LLDD_SHISS ;  B4SMK1, LLDD_STRM5 ;  B2FIJ0, LLDD_STRMK ;
DR   Q9KKW6, LLDD_VIBCH ;  C3LWP7, LLDD_VIBCM ;  Q87G18, LLDD_VIBPA ;
DR   Q8PR33, LLDD_XANAC ;  Q3BZH2, LLDD_XANC5 ;  Q4V0H2, LLDD_XANC8 ;
DR   B0RLM2, LLDD_XANCB ;  Q8PE75, LLDD_XANCP ;  Q2P9K0, LLDD_XANOM ;
DR   B2SUY3, LLDD_XANOP ;  Q5H6Z4, LLDD_XANOR ;  A7IMB0, LLDD_XANP2 ;
DR   A7FJF0, LLDD_YERP3 ;  Q1C9P0, LLDD_YERPA ;  B2JZQ1, LLDD_YERPB ;
DR   Q8ZFV8, LLDD_YERPE ;  A9R623, LLDD_YERPG ;  Q1CGZ1, LLDD_YERPN ;
DR   A4TKI4, LLDD_YERPP ;  Q66C32, LLDD_YERPS ;  B1JPU0, LLDD_YERPY ;
//
ID   1.1.2.4
DE   D-lactate dehydrogenase (cytochrome).
AN   D-lactate ferricytochrome c oxidoreductase.
AN   Lactic acid dehydrogenase.
CA   (R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c.
CF   FAD.
DR   Q12627, DLD1_KLULA ;  P32891, DLD1_YEAST ;  P46681, DLD2_YEAST ;
DR   P39976, DLD3_YEAST ;  Q94AX4, DLD_ARATH  ;  Q86WU2, LDHD_HUMAN ;
DR   Q7TNG8, LDHD_MOUSE ;  Q9C1X2, YN53_SCHPO ;
//
ID   1.1.2.5
DE   D-lactate dehydrogenase (cytochrome c-553).
CA   (R)-lactate + 2 ferricytochrome c-553 = pyruvate + 2 ferrocytochrome
CA   c-553.
CC   -!- From Desulfovibrio vulgaris.
//
ID   1.1.2.6
DE   Polyvinyl alcohol dehydrogenase (cytochrome).
AN   PVA dehydrogenase.
AN   PVADH.
CA   Polyvinyl alcohol + ferricytochrome c = oxidized polyvinyl alcohol +
CA   ferrocytochrome c + H(+).
CF   Pyrroloquinoline quinone.
CC   -!- The enzyme is involved in bacterial polyvinyl alcohol degradation.
CC   -!- Some Gram-negative bacteria degrade polyvinyl alcohol by importing it
CC       into the periplasmic space, where it is oxidized by polyvinyl alcohol
CC       dehydrogenase, an enzyme that is coupled to the respiratory chain via
CC       cytochrome c.
CC   -!- Formerly EC 1.1.99.23.
//
ID   1.1.2.7
DE   Methanol dehydrogenase (cytochrome c).
AN   MDH.
AN   Methanol dehydrogenase.
CA   A primary alcohol + 2 cytochrome c(L)  = an aldehyde + 2 reduced
CA   cytochrome c(L).
CF   Pyrroloquinoline quinone.
CC   -!- A periplasmic quinoprotein alcohol dehydrogenase that only occurs in
CC       methylotrophic bacteria.
CC   -!- It uses the novel specific cytochrome c(L) as acceptor.
CC   -!- Acts on a wide range of primary alcohols, including ethanol,
CC       duodecanol, chloroethanol, cinnamyl alcohol, and also formaldehyde.
CC   -!- Activity is stimulated by ammonia or methylamine.
CC   -!- It is usually assayed with phenazine methosulfate.
CC   -!- Like all other quinoprotein alcohol dehydrogenases it has an 8-bladed
CC       'propeller' structure, a calcium ion bound to the PQQ in the active
CC       site and an unusual disulfide ring structure in close proximity to
CC       the PQQ.
CC   -!- It differs from EC 1.1.2.8, alcohol dehydrogenase (cytochrome c),
CC       in having a high affinity for methanol and in having a second
CC       essential small subunit (no known function).
CC   -!- Formerly EC 1.1.99.8.
DR   P18278, DHET_ACEAC ;  P16027, DHM1_METEA ;  P38539, DHM1_METME ;
DR   P15279, DHM1_METOR ;  P12293, DHM1_PARDE ;  P14775, DHM2_METEA ;
DR   P38540, DHM2_METME ;  Q09053, DHM2_METSP ;  P29898, DHM2_PARDE ;
//
ID   1.1.2.8
DE   Alcohol dehydrogenase (cytochrome c).
CA   A primary alcohol + 2 cytochrome c = an aldehyde + 2 reduced cytochrome
CA   c.
CC   -!- A periplasmic PQQ-containing quinoprotein.
CC   -!- Occurs in Pseudomonas and Rhodopseudomonas.
CC   -!- The enzyme from Pseudomonas aeruginosa uses a specific inducible
CC       cytochrome c(550) as electron acceptor.
CC   -!- Acts on a wide range of primary and secondary alcohols, but not
CC       methanol.
CC   -!- It has a homodimeric structure (contrasting with the heterotetrameric
CC       structure of EC 1.1.2.7, methanol dehydrogenase (cytochrome c)).
CC   -!- It is routinely assayed with phenazine methosulfate as electron
CC       acceptor.
CC   -!- Activity is stimulated by ammonia or amines.
CC   -!- Like all other quinoprotein alcohol dehydrogenases it has an 8-bladed
CC       'propeller' structure, a calcium ion bound to the PQQ in the active
CC       site and an unusual disulfide ring structure in close proximity to
CC       the PQQ.
CC   -!- Formerly EC 1.1.99.8.
DR   Q44002, DHET_ACEEU ;  P28036, DHET_ACEPO ;  O05542, DHET_GLUOX ;
DR   Q9Z4J7, EXAA_PSEAE ;
//
ID   1.1.3.1
DE   Transferred entry: 1.1.3.15.
//
ID   1.1.3.2
DE   Transferred entry: 1.13.12.4.
//
ID   1.1.3.3
DE   Malate oxidase.
AN   Malic oxidase.
CA   (S)-malate + O(2) = oxaloacetate + H(2)O(2).
CF   FAD.
//
ID   1.1.3.4
DE   Glucose oxidase.
AN   Beta-D-glucose:oxygen 1-oxido-reductase.
AN   D-glucose-1-oxidase.
AN   Glucose aerodehydrogenase.
AN   Glucose oxyhydrase.
AN   GOD.
CA   Beta-D-glucose + O(2) = D-glucono-1,5-lactone + H(2)O(2).
CF   FAD.
PR   PROSITE; PDOC00543;
DR   P13006, GOX_ASPNG  ;  P81156, GOX_PENAG  ;  Q92452, GOX_TALFL  ;
//
ID   1.1.3.5
DE   Hexose oxidase.
CA   Beta-D-glucose + O(2) = D-glucono-1,5-lactone + H(2)O(2).
CF   Copper.
CC   -!- Also oxidizes D-galactose, D-mannose, maltose, lactose and
CC       cellobiose.
//
ID   1.1.3.6
DE   Cholesterol oxidase.
AN   Cholesterol-O(2) oxidoreductase.
CA   Cholesterol + O(2) = cholest-4-en-3-one + H(2)O(2).
CF   FAD.
PR   PROSITE; PDOC00543;
DR   P22637, CHOD_BREST ;  Q57307, CHOD_MYCTU ;  P12676, CHOD_STRS0 ;
//
ID   1.1.3.7
DE   Aryl-alcohol oxidase.
AN   Veratryl alcohol oxidase.
CA   An aromatic primary alcohol + O(2) = an aromatic aldehyde + H(2)O(2).
CC   -!- Oxidizes many primary alcohols containing an aromatic ring; best
CC       substrates are (2-naphthyl)methanol and 3-methoxybenzyl alcohol.
//
ID   1.1.3.8
DE   L-gulonolactone oxidase.
AN   GLO.
AN   L-gulono-gamma-lactone oxidase.
CA   (1) L-gulono-1,4-lactone + O(2) = L-xylo-hex-2-ulono-1,4-lactone +
CA   H(2)O(2).
CA   (2) L-xylo-hex-2-ulono-1,4-lactone = L-ascorbate.
CF   FAD.
CC   -!- The product spontaneously isomerizes to L-ascorbate.
CC   -!- While most higher animals can synthesize ascorbic acid, primates and
CC       guinea pigs cannot.
PR   PROSITE; PDOC00674;
DR   Q3ZC33, GGLO_BOVIN ;  P58710, GGLO_MOUSE ;  Q8HXW0, GGLO_PIG   ;
DR   P10867, GGLO_RAT   ;  Q90YK3, GGLO_SCYTO ;
//
ID   1.1.3.9
DE   Galactose oxidase.
AN   Beta-galactose oxidase.
CA   D-galactose + O(2) = D-galacto-hexodialdose + H(2)O(2).
CF   Copper.
DR   Q01745, GAOA_GIBZE ;
//
ID   1.1.3.10
DE   Pyranose oxidase.
AN   Glucose 2-oxidase.
CA   D-glucose + O(2) = 2-dehydro-D-glucose + H(2)O(2).
CF   FAD.
CC   -!- Also oxidizes D-xylose, L-sorbose and D-glucono-1,5-lactone, which
CC       have the same ring conformation and configuration at C-2, C-3 and
CC       C-4.
DR   Q5B2E9, P2OX_EMENI ;  Q75ZP8, P2OX_LYOSH ;  Q8J136, P2OX_PENSG ;
DR   Q6QWR1, P2OX_PHACH ;  Q6UG02, P2OX_PHLGI ;  P59097, P2OX_TRAHI ;
DR   Q5G234, P2OX_TRAPU ;  P79076, P2OX_TRAVE ;  Q8J2V8, P2OX_TRIMT ;
//
ID   1.1.3.11
DE   L-sorbose oxidase.
CA   L-sorbose + O(2) = 5-dehydro-D-fructose + H(2)O(2).
CC   -!- Also acts on D-glucose, D-galactose and D-xylose, but not on
CC       D-fructose.
CC   -!- 2,6-dichloroindophenol can act as acceptor.
//
ID   1.1.3.12
DE   Pyridoxine 4-oxidase.
AN   Pyridoxin 4-oxidase.
CA   Pyridoxine + O(2) = pyridoxal + H(2)O(2).
CF   FAD.
CC   -!- 2,6-dichloroindophenol can act as acceptor.
PR   PROSITE; PDOC00543;
DR   Q9AJD6, PNO_MICLT  ;
//
ID   1.1.3.13
DE   Alcohol oxidase.
AN   AOX.
AN   Methanol oxidase.
CA   A primary alcohol + O(2) = an aldehyde + H(2)O(2).
CF   FAD.
CC   -!- Acts on lower primary alcohols and unsaturated alcohols but branched-
CC       chain and secondary alcohols are not attacked.
PR   PROSITE; PDOC00543;
DR   Q00922, ALOX_CANBO ;  P04841, ALOX_PICAN ;  P04842, ALOX_PICPA ;
//
ID   1.1.3.14
DE   Catechol oxidase (dimerizing).
CA   4 catechol + 3 O(2) = 2 dibenzo[1,4]dioxin-2,3-dione + 6 H(2)O.
//
ID   1.1.3.15
DE   (S)-2-hydroxy-acid oxidase.
AN   Glycolate oxidase.
AN   Hydroxy-acid oxidase A.
AN   Hydroxy-acid oxidase B.
CA   (S)-2-hydroxy acid + O(2) = 2-oxo acid + H(2)O(2).
CF   FMN.
CC   -!- Exists as two major isoenzymes; the A form preferentially oxidizes
CC       short-chain aliphatic hydroxy acids; the B form preferentially
CC       oxidizes long-chain and aromatic hydroxy acids.
CC   -!- The rat isoenzyme B also acts as EC 1.4.3.2.
CC   -!- Formerly EC 1.1.3.1.
PR   PROSITE; PDOC00482;
DR   Q9LRR9, GLO1_ARATH ;  B8AKX6, GLO1_ORYSI ;  Q10CE4, GLO1_ORYSJ ;
DR   Q9LRS0, GLO2_ARATH ;  Q01KC2, GLO2_ORYSI ;  Q7XPR4, GLO2_ORYSJ ;
DR   Q24JJ8, GLO3_ARATH ;  B8AUI3, GLO3_ORYSI ;  Q7FAS1, GLO3_ORYSJ ;
DR   Q9LJH5, GLO4_ARATH ;  B8B8K5, GLO4_ORYSI ;  Q8H3I4, GLO4_ORYSJ ;
DR   O49506, GLO5_ARATH ;  B8B7C5, GLO5_ORYSI ;  Q6YT73, GLO5_ORYSJ ;
DR   P05414, GOX_SPIOL  ;  Q9UJM8, HAOX1_HUMAN;  Q9WU19, HAOX1_MOUSE;
DR   Q3ZBW2, HAOX2_BOVIN;  Q9NYQ3, HAOX2_HUMAN;  Q9NYQ2, HAOX2_MOUSE;
DR   Q07523, HAOX2_RAT  ;  Q54E41, HAOX_DICDI ;  P37339, LHGO_ECOLI ;
//
ID   1.1.3.16
DE   Ecdysone oxidase.
CA   Ecdysone + O(2) = 3-dehydroecdysone + H(2)O(2).
CC   -!- 2,6-dichloroindophenol can act as acceptor.
//
ID   1.1.3.17
DE   Choline oxidase.
CA   Choline + 2 O(2) + H(2)O = betaine + 2 H(2)O(2).
CF   FAD.
CC   -!- In many bacteria, plants and animals, the osmoprotectant betaine is
CC       synthesized using different enzymes to catalyze the conversion of (1)
CC       choline into betaine aldehyde and (2) betaine aldehyde into betaine.
CC   -!- In plants, the first reaction is catalyzed by EC 1.14.15.7, whereas
CC       in animals and many bacteria, it is catalyzed by either EC 1.1.99.1
CC       or EC 1.1.3.17.
CC   -!- The enzyme involved in the second step, EC 1.2.1.8, appears to be the
CC       same in those plants, animals and bacteria that use two separate
CC       enzymes.
DR   P16101, CHOX_ALCSP ;
//
ID   1.1.3.18
DE   Secondary-alcohol oxidase.
CA   A secondary alcohol + O(2) = a ketone + H(2)O(2).
CF   Iron.
CC   -!- Acts on secondary alcohols with five or more carbons, and polyvinyl
CC       alcohols with molecular mass over 300 Da.
//
ID   1.1.3.19
DE   4-hydroxymandelate oxidase.
CA   (S)-2-hydroxy-2-(4-hydroxyphenyl)acetate + O(2) = 4-hydroxybenzaldehyde +
CA   CO(2) + H(2)O(2).
CF   FAD; Manganese.
//
ID   1.1.3.20
DE   Long-chain-alcohol oxidase.
CA   A long-chain alcohol + O(2) = a long-chain aldehyde + H(2)O(2).
CC   -!- Oxidizes long-chain fatty alcohols; best substrate is dodecyl
CC       alcohol.
PR   PROSITE; PDOC00543;
DR   Q9ZWB9, FAO1_ARATH ;  B5WWZ8, FAO1_LOTJA ;  B5WWZ9, FAO2_LOTJA ;
DR   Q9LW56, FAO3_ARATH ;  O65709, FAO4A_ARATH;  Q94BP3, FAO4B_ARATH;
//
ID   1.1.3.21
DE   Glycerol-3-phosphate oxidase.
AN   Alpha-glycerophosphate oxidase.
CA   sn-glycerol 3-phosphate + O(2) = glycerone phosphate + H(2)O(2).
CF   FAD.
DR   O86963, GLPO_ENTCA ;  Q9CG65, GLPO_LACLA ;  Q99YI8, GLPO_STRP1 ;
DR   P0DB20, GLPO_STRP3 ;  Q5XAK0, GLPO_STRP6 ;  Q8NZX0, GLPO_STRP8 ;
DR   P35596, GLPO_STRPN ;  P0DB21, GLPO_STRPQ ;
//
ID   1.1.3.22
DE   Transferred entry: 1.17.3.2.
//
ID   1.1.3.23
DE   Thiamine oxidase.
AN   Thiamine dehydrogenase.
CA   Thiamine + 2 O(2) + H(2)O = thiamine acetic acid + 2 H(2)O(2).
CF   FAD.
CC   -!- The product differs from thiamine in replacement of -CH(2)-CH(2)-OH
CC       by -CH(2)-COOH; the two-step oxidation proceeds without the release
CC       of the intermediate aldehyde from the enzyme.
//
ID   1.1.3.24
DE   Transferred entry: 1.3.3.12.
//
ID   1.1.3.25
DE   Transferred entry: 1.1.99.18.
//
ID   1.1.3.26
DE   Transferred entry: 1.21.3.2.
//
ID   1.1.3.27
DE   Hydroxyphytanate oxidase.
CA   L-2-hydroxyphytanate + O(2) = 2-oxophytanate + H(2)O(2).
//
ID   1.1.3.28
DE   Nucleoside oxidase.
CA   Inosine + O(2) = 9-riburonosylhypoxanthine + 2 H(2)O.
CC   -!- Other purine and pyrimidine nucleosides (as well as
CC       2'-deoxynucleosides) are substrates, but ribose and nucleotides are
CC       not substrates.
CC   -!- The overall reaction takes place in two separate steps:
CC       (1) 2 inosine + O(2) = 2 5'-dehydroinosine + 2 H(2)O.
CC       (2) 2 5'-dehydroinosine + O(2) = 2 9-riburonosylhypoxanthine +
CC       2 H(2)O.
CC   -!- The 5'-dehydro nucleoside is being released from the enzyme to serve
CC       as substrate for the second reaction.
CC   -!- Differs from EC 1.1.3.39 as it produces water rather than hydrogen
CC       peroxide.
//
ID   1.1.3.29
DE   N-acylhexosamine oxidase.
CA   N-acetyl-D-glucosamine + O(2) = N-acetyl-D-glucosaminate + H(2)O(2).
CC   -!- Also acts on N-glycolylglucosamine, N-acetylgalactosamine and, more
CC       slowly, on N-acetylmannosamine.
//
ID   1.1.3.30
DE   Polyvinyl-alcohol oxidase.
AN   PVA oxidase.
CA   Polyvinyl alcohol + O(2) = oxidized polyvinyl alcohol + H(2)O(2).
//
ID   1.1.3.31
DE   Deleted entry.
//
ID   1.1.3.32
DE   Transferred entry: 1.14.21.1.
//
ID   1.1.3.33
DE   Transferred entry: 1.14.21.2.
//
ID   1.1.3.34
DE   Transferred entry: 1.14.21.3.
//
ID   1.1.3.35
DE   Transferred entry: 1.14.21.4.
//
ID   1.1.3.36
DE   Transferred entry: 1.14.21.5.
//
ID   1.1.3.37
DE   D-arabinono-1,4-lactone oxidase.
AN   D-arabinono-gamma-lactone oxidase.
CA   D-arabinono-1,4-lactone + O(2) = dehydro-D-arabinono-1,4-lactone +
CA   H(2)O(2).
CF   FAD.
PR   PROSITE; PDOC00674;
DR   Q752Y3, ALO_ASHGO  ;  O93852, ALO_CANAL  ;  Q6FS20, ALO_CANGA  ;
DR   Q6BZA0, ALO_DEBHA  ;  Q6CSY3, ALO_KLULA  ;  Q7SGY1, ALO_NEUCR  ;
DR   Q9HDX8, ALO_SCHPO  ;  Q6CG88, ALO_YARLI  ;  P54783, ALO_YEAST  ;
//
ID   1.1.3.38
DE   Vanillyl-alcohol oxidase.
AN   4-hydroxy-2-methoxybenzyl alcohol oxidase.
CA   Vanillyl alcohol + O(2) = vanillin + H(2)O(2).
CF   FAD.
CC   -!- Converts a wide range of 4-hydroxybenzyl alcohols and
CC       4-hydroxybenzylamines into the corresponding aldehydes.
CC   -!- The allyl group of 4-allylphenols is also converted into the
CC       -CH=CH-CH(2)OH group.
DR   P56216, VAOX_PENSI ;
//
ID   1.1.3.39
DE   Nucleoside oxidase (H(2)O(2)-forming).
CA   Adenosine + 2 O(2) = 9-riburonosyladenine + 2 H(2)O(2).
CF   FAD; Heme.
CC   -!- Other purine and pyrimidine nucleosides (as well as
CC       2'-deoxynucleosides and arabinosides) are substrates, but ribose and
CC       nucleotides are not substrates.
CC   -!- The overall reaction takes place in two separate steps:
CC       (1) Adenosine + O(2) = 5'-dehydroadenosine + H(2)O(2).
CC       (2) 5'-dehydroadenosine + O(2) = 9-riburonosyladenine + H(2)O(2).
CC   -!- The 5'-dehydro nucleoside is being released from the enzyme to serve
CC       as substrate for the second reaction.
CC   -!- Differs from EC 1.1.3.28 as it produces hydrogen peroxide rather than
CC       water.
//
ID   1.1.3.40
DE   D-mannitol oxidase.
AN   D-arabinitol oxidase.
AN   Mannitol oxidase.
CA   Mannitol + O(2) = mannose + H(2)O(2).
CC   -!- Also catalyzes the oxidation of D-arabinitol and, to a lesser extent,
CC       D-glucitol (sorbitol), whereas L-arabinitol is not a good substrate.
CC   -!- The enzyme from the snails Helix aspersa and Arion ater is found in a
CC       specialized tubular organelle that has been termed the mannosome.
//
ID   1.1.3.41
DE   Alditol oxidase.
AN   Xylitol oxidase.
CA   An alditol + O(2) = an aldose + H(2)O(2).
CF   FAD.
CC   -!- While xylitol (five carbons) and sorbitol (6 carbons) are the
CC       preferred substrates, other alditols, including L-threitol (four
CC       carbons), D-arabitol (five carbons), D-galactitol (six carbons) and
CC       D-mannitol (six carbons) can also act as substrates, but more slowly.
PR   PROSITE; PDOC00674;
DR   Q9ZBU1, XYOA_STRCO ;  Q9KX73, XYOA_STRSI ;
//
ID   1.1.4.1
DE   Vitamin-K-epoxide reductase (warfarin-sensitive).
AN   Phylloquinone epoxide reductase.
AN   Vitamin K1 epoxide reductase.
CA   2-methyl-3-phytyl-1,4-naphthoquinone + oxidized dithiothreitol = 2,3-
CA   epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-
CA   dithiothreitol.
CC   -!- In the reverse reaction, vitamin K 2,3-epoxide is reduced to vitamin
CC       K and possibly to vitamin K hydroquinone by 1,4-dithioerythritol,
CC       which is oxidized to a disulfide; some other dithiols and
CC       4-butanethiol can also act.
CC   -!- Inhibited strongly by warfarin (cf. EC 1.1.4.2).
DR   Q6B4J2, VKOR1_BOVIN;  Q9BQB6, VKOR1_HUMAN;  Q9CRC0, VKOR1_MOUSE;
DR   Q6TEK4, VKOR1_RAT  ;
//
ID   1.1.4.2
DE   Vitamin-K-epoxide reductase (warfarin-insensitive).
AN   Vitamin K 2,3-epoxide reductase.
CA   3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone + oxidized
CA   dithiothreitol = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-
CA   naphthoquinone + 1,4-dithiothreitol.
CC   -!- In the reverse reaction, vitamin K 2,3-epoxide is reduced to
CC       3-hydroxy- (and 2-hydroxy-) vitamin K by 1,4-dithioerythritol, which
CC       is oxidized to a disulfide.
CC   -!- Not inhibited by warfarin (cf. EC 1.1.4.1).
//
ID   1.1.5.1
DE   Deleted entry.
//
ID   1.1.5.2
DE   Quinoprotein glucose dehydrogenase.
AN   D-glucose:(pyrroloquinoline-quinone) 1-oxidoreductase.
AN   Glucose dehydrogenase (PQQ-dependent).
AN   Glucose dehydrogenase (pyrroloquinoline-quinone).
AN   Quinoprotein D-glucose dehydrogenase.
CA   D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol.
CF   Calcium or magnesium; Pyrroloquinoline quinone.
CC   -!- Integral membrane protein containing PQQ as prosthetic group.
CC   -!- It also contains bound ubiquinone and Mg(2+) or Ca(2+).
CC   -!- Electron acceptor is membrane ubiquinone but usually assayed with
CC       phenazine methosulfate.
CC   -!- Like in all other quinoprotein alcohol dehydrogenases the catalytic
CC       domain has an 8-bladed 'propeller' structure.
CC   -!- It occurs in a wide range of bacteria.
CC   -!- Catalyzes a direct oxidation of the pyranose form of D-glucose to the
CC       lactone and thence to D-gluconate in the periplasm.
CC   -!- Oxidizes other monosaccharides including the pyranose forms of
CC       pentoses.
CC   -!- Formerly EC 1.1.99.17.
PR   PROSITE; PDOC00375;
DR   P13650, DHGB_ACICA ;  P15877, DHG_ECOLI  ;  P27175, DHG_GLUOX  ;
//
ID   1.1.5.3
DE   Glycerol-3-phosphate dehydrogenase.
AN   FAD-dependent glycerol-3-phosphate dehydrogenase.
AN   Flavin-linked glycerol-3-phosphate dehydrogenase.
AN   Glycerol-3-phosphate CoQ reductase.
AN   Glycerophosphate dehydrogenase.
AN   L-glycerophosphate dehydrogenase.
AN   sn-glycerol-3-phosphate dehydrogenase.
CA   sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.
CF   Flavin.
CC   -!- An essential membrane enzyme, functioning at the central junction of
CC       glycolysis, respiration and phospholipid biosynthesis.
CC   -!- In bacteria, the enzyme is localized to the cytoplasmic membrane,
CC       while in eukaryotes it is tightly bound to the outer surface of the
CC       inner mitochondrial membrane.
CC   -!- In eukaryotes, this enzyme, together with the cytosolic enzyme
CC       EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH
CC       produced in the cytosol, primarily from glycolysis, can be reoxidized
CC       to NAD(+) by the mitochondrial electron-transport chain.
CC   -!- This shuttle plays a critical role in transferring reducing
CC       equivalents from cytosolic NADH into the mitochondrial matrix.
CC   -!- Insect flight muscle uses only CoQ(10) as the physiological quinone
CC       whereas hamster and rat mitochondria use mainly CoQ(9).
CC   -!- The enzyme is activated by calcium.
CC   -!- Formerly EC 1.1.2.1 and EC 1.1.99.5.
PR   PROSITE; PDOC00753;
DR   P0A9C1, GLPA_ECO57 ;  P0A9C0, GLPA_ECOLI ;  P43799, GLPA_HAEIN ;
DR   P0A9C2, GLPA_SHIFL ;  A3MZ98, GLPB_ACTP2 ;  B3H0P4, GLPB_ACTP7 ;
DR   B0BTN3, GLPB_ACTPJ ;  A6VKT7, GLPB_ACTSZ ;  A8ADX8, GLPB_CITK8 ;
DR   A7ZP63, GLPB_ECO24 ;  B7UFQ3, GLPB_ECO27 ;  B7MG07, GLPB_ECO45 ;
DR   B7LAR0, GLPB_ECO55 ;  Q8XE13, GLPB_ECO57 ;  B5YX30, GLPB_ECO5E ;
DR   B7NN59, GLPB_ECO7I ;  B7MXS2, GLPB_ECO81 ;  B7M5S7, GLPB_ECO8A ;
DR   C4ZU83, GLPB_ECOBW ;  B1X8D6, GLPB_ECODH ;  A8A2A7, GLPB_ECOHS ;
DR   A1AD94, GLPB_ECOK1 ;  Q0TFK1, GLPB_ECOL5 ;  Q8FFN4, GLPB_ECOL6 ;
DR   B1IXU6, GLPB_ECOLC ;  P13033, GLPB_ECOLI ;  B7N5K6, GLPB_ECOLU ;
DR   B6I7H1, GLPB_ECOSE ;  B1LLJ4, GLPB_ECOSM ;  Q1R9H5, GLPB_ECOUT ;
DR   A4WCP1, GLPB_ENT38 ;  Q6CZI7, GLPB_ERWCT ;  B7LM86, GLPB_ESCF3 ;
DR   Q7VM49, GLPB_HAEDU ;  Q4QMN2, GLPB_HAEI8 ;  A5UE48, GLPB_HAEIE ;
DR   A5UHH2, GLPB_HAEIG ;  P43800, GLPB_HAEIN ;  B8F6F3, GLPB_HAEPS ;
DR   Q0I239, GLPB_HAES1 ;  B0UVX7, GLPB_HAES2 ;  B0R6S4, GLPB_HALS3 ;
DR   Q9HNS3, GLPB_HALSA ;  B5XNY5, GLPB_KLEP3 ;  A6TBU4, GLPB_KLEP7 ;
DR   Q65R09, GLPB_MANSM ;  Q9CL07, GLPB_PASMU ;  C6DH98, GLPB_PECCP ;
DR   Q6LSE4, GLPB_PHOPR ;  B5EYX0, GLPB_SALA4 ;  A9MJD3, GLPB_SALAR ;
DR   Q57M68, GLPB_SALCH ;  B5FNS6, GLPB_SALDC ;  B5R258, GLPB_SALEP ;
DR   B5RCB0, GLPB_SALG2 ;  B4TBF2, GLPB_SALHS ;  B4SYV7, GLPB_SALNS ;
DR   Q5PI45, GLPB_SALPA ;  A9N5C9, GLPB_SALPB ;  B5BCR1, GLPB_SALPK ;
DR   B4TPG8, GLPB_SALSV ;  Q8Z553, GLPB_SALTI ;  Q8ZNG4, GLPB_SALTY ;
DR   B2TW33, GLPB_SHIB3 ;  Q31Z75, GLPB_SHIBS ;  Q32DU5, GLPB_SHIDS ;
DR   Q0T2N9, GLPB_SHIF8 ;  Q83ML0, GLPB_SHIFL ;  Q3YZW4, GLPB_SHISS ;
DR   A5EZR7, GLPB_VIBC3 ;  Q9KLJ6, GLPB_VIBCH ;  C3LW14, GLPB_VIBCM ;
DR   Q5E0X7, GLPB_VIBF1 ;  B5ET22, GLPB_VIBFM ;  Q8D7Y4, GLPB_VIBVU ;
DR   Q7MF00, GLPB_VIBVY ;  A1JIB0, GLPB_YERE8 ;  Q1CBK6, GLPB_YERPA ;
DR   Q8ZAH6, GLPB_YERPE ;  Q1CNF8, GLPB_YERPN ;  Q66FX5, GLPB_YERPS ;
DR   P64183, GLPD1_MYCBO;  P64182, GLPD1_MYCTU;  P64185, GLPD2_MYCBO;
DR   P64184, GLPD2_MYCTU;  P18158, GLPD_BACSU ;  P13035, GLPD_ECOLI ;
DR   P53435, GLPD_MYCLE ;  P52111, GLPD_PSEAE ;  O83004, GLPD_PSETO ;
DR   Q2FHD8, GLPD_STAA3 ;  Q2FYZ4, GLPD_STAA8 ;  Q2YXR5, GLPD_STAAB ;
DR   Q5HGD1, GLPD_STAAC ;  Q99UH2, GLPD_STAAM ;  Q7A5V7, GLPD_STAAN ;
DR   Q6GHD4, GLPD_STAAR ;  Q6G9R2, GLPD_STAAS ;  Q7A105, GLPD_STAAW ;
DR   Q5HPP0, GLPD_STAEQ ;  Q8CPE6, GLPD_STAES ;  Q4L608, GLPD_STAHJ ;
DR   Q49X94, GLPD_STAS1 ;  P74257, GLPD_SYNY3 ;  Q8SR40, GPDH_ENCCU ;
DR   A6QLU1, GPDM_BOVIN ;  P90795, GPDM_CAEEL ;  Q54QC1, GPDM_DICDI ;
DR   P43304, GPDM_HUMAN ;  Q4R755, GPDM_MACFA ;  A7DZP8, GPDM_MESAU ;
DR   Q64521, GPDM_MOUSE ;  P35571, GPDM_RAT   ;  O14400, GPDM_SCHPO ;
DR   P32191, GPDM_YEAST ;  Q9SS48, SDP6_ARATH ;
//
ID   1.1.5.4
DE   Malate dehydrogenase (quinone).
AN   FAD-dependent malate dehydrogenase.
AN   Malate dehydrogenase (acceptor).
AN   Malate quinone oxidoreductase.
AN   MQO.
CA   (S)-malate + a quinone = oxaloacetate + reduced quinone.
CF   FAD.
CC   -!- Vitamin K and several other quinones can act as acceptors.
CC   -!- Different from EC 1.1.1.37, EC 1.1.1.82 and EC 1.1.1.299.
CC   -!- Formerly EC 1.1.99.16.
DR   Q9HYF4, MQO1_PSEAE ;  Q88PU7, MQO1_PSEPK ;  Q5HDJ0, MQO1_STAAC ;
DR   P65421, MQO1_STAAM ;  P65422, MQO1_STAAN ;  Q6GE66, MQO1_STAAR ;
DR   Q6G6V5, MQO1_STAAS ;  P65423, MQO1_STAAW ;  Q5HLN0, MQO1_STAEQ ;
DR   Q8CN91, MQO1_STAES ;  Q9HVF1, MQO2_PSEAE ;  Q88NF9, MQO2_PSEPK ;
DR   Q5HCU5, MQO2_STAAC ;  P65424, MQO2_STAAM ;  P99115, MQO2_STAAN ;
DR   Q6GDJ6, MQO2_STAAR ;  Q6G669, MQO2_STAAS ;  Q8NUM4, MQO2_STAAW ;
DR   Q5HKN2, MQO2_STAEQ ;  Q8CQ96, MQO2_STAES ;  Q88IS4, MQO3_PSEPK ;
DR   Q5HKD6, MQO3_STAEQ ;  Q8CQE8, MQO3_STAES ;  Q5HL19, MQO4_STAEQ ;
DR   Q8CMY4, MQO4_STAES ;  Q6FDG0, MQO_ACIAD  ;  B7GYG6, MQO_ACIB3  ;
DR   B7I894, MQO_ACIB5  ;  B2HV78, MQO_ACIBC  ;  A3M361, MQO_ACIBT  ;
DR   B0V946, MQO_ACIBY  ;  A3N262, MQO_ACTP2  ;  B3H2E6, MQO_ACTP7  ;
DR   B0BR13, MQO_ACTPJ  ;  Q8UH73, MQO_AGRT5  ;  A1R7M9, MQO_ARTAT  ;
DR   B8HAT7, MQO_ARTCA  ;  A8I2M2, MQO_AZOC5  ;  C3NZS9, MQO_BACAA  ;
DR   C3LEY8, MQO_BACAC  ;  A0RFE8, MQO_BACAH  ;  Q81P44, MQO_BACAN  ;
DR   B7JSX2, MQO_BACC0  ;  Q735Z0, MQO_BACC1  ;  B7ILI6, MQO_BACC2  ;
DR   C1EYZ6, MQO_BACC3  ;  B7H655, MQO_BACC4  ;  B7HVJ1, MQO_BACC7  ;
DR   A7GQI9, MQO_BACCN  ;  B9J484, MQO_BACCQ  ;  Q81C25, MQO_BACCR  ;
DR   Q639Y8, MQO_BACCZ  ;  Q9Z9Q7, MQO_BACHD  ;  Q6HHE0, MQO_BACHK  ;
DR   A9VJG1, MQO_BACWK  ;  Q1LU84, MQO_BAUCH  ;  Q7VRS0, MQO_BLOFL  ;
DR   Q492E3, MQO_BLOPB  ;  Q2KX12, MQO_BORA1  ;  Q89XM4, MQO_BRAJA  ;
DR   C0Z9W8, MQO_BREBN  ;  Q1BKI8, MQO_BURCA  ;  A0AWY9, MQO_BURCH  ;
DR   Q390Q5, MQO_BURS3  ;  P56954, MQO_CAMJE  ;  Q1QUD2, MQO_CHRSD  ;
DR   A8AE07, MQO_CITK8  ;  A5CPE3, MQO_CLAM3  ;  B0RIH2, MQO_CLAMS  ;
DR   C3PH30, MQO_CORA7  ;  Q6NGL9, MQO_CORDI  ;  Q8FP91, MQO_COREF  ;
DR   A4QF08, MQO_CORGB  ;  O69282, MQO_CORGL  ;  Q4JV42, MQO_CORJK  ;
DR   A7ZP32, MQO_ECO24  ;  B7UFM4, MQO_ECO27  ;  B7MFC3, MQO_ECO45  ;
DR   B7LAN4, MQO_ECO55  ;  Q8XE45, MQO_ECO57  ;  B5YX02, MQO_ECO5E  ;
DR   B7NN21, MQO_ECO7I  ;  B7MXP1, MQO_ECO81  ;  B7M5Q1, MQO_ECO8A  ;
DR   C4ZU53, MQO_ECOBW  ;  B1X8A6, MQO_ECODH  ;  A8A273, MQO_ECOHS  ;
DR   A1AD63, MQO_ECOK1  ;  Q0TFN1, MQO_ECOL5  ;  Q8FFQ5, MQO_ECOL6  ;
DR   B1IY62, MQO_ECOLC  ;  P33940, MQO_ECOLI  ;  B7N5H2, MQO_ECOLU  ;
DR   B6I1A8, MQO_ECOSE  ;  B1LKV7, MQO_ECOSM  ;  Q1R9K7, MQO_ECOUT  ;
DR   A4WCM3, MQO_ENT38  ;  A7MNG1, MQO_ENTS8  ;  Q6D2L3, MQO_ERWCT  ;
DR   B7LMB2, MQO_ESCF3  ;  B1YG64, MQO_EXIS2  ;  C4L056, MQO_EXISA  ;
DR   A5FGX2, MQO_FLAJ1  ;  A6H0E6, MQO_FLAPJ  ;  Q5L055, MQO_GEOKA  ;
DR   C5DAE0, MQO_GEOSW  ;  A4IMR6, MQO_GEOTN  ;  Q5FP90, MQO_GLUOX  ;
DR   Q0BTB0, MQO_GRABC  ;  Q7VPC3, MQO_HAEDU  ;  Q2SF51, MQO_HAHCH  ;
DR   Q17VT7, MQO_HELAH  ;  Q7VFF6, MQO_HELHP  ;  B6JPI8, MQO_HELP2  ;
DR   Q1CV68, MQO_HELPH  ;  Q9ZMY5, MQO_HELPJ  ;  O24913, MQO_HELPY  ;
DR   O32719, MQO_KLEPN  ;  B2GFJ0, MQO_KOCRD  ;  Q6AGY2, MQO_LEIXX  ;
DR   B1HNU2, MQO_LYSSC  ;  Q1GXL1, MQO_METFK  ;  C5CAA3, MQO_MICLC  ;
DR   P65420, MQO_MYCBO  ;  A1KMJ5, MQO_MYCBP  ;  C1AFW6, MQO_MYCBT  ;
DR   A4TCE3, MQO_MYCGI  ;  B2HJU4, MQO_MYCMM  ;  Q73VU0, MQO_MYCPA  ;
DR   A0QVL2, MQO_MYCS2  ;  A3PY62, MQO_MYCSJ  ;  A1UEQ5, MQO_MYCSK  ;
DR   Q1BAA7, MQO_MYCSS  ;  A5U6K4, MQO_MYCTA  ;  P65419, MQO_MYCTU  ;
DR   A1T7G4, MQO_MYCVP  ;  Q5F5E9, MQO_NEIG1  ;  B4RQQ5, MQO_NEIG2  ;
DR   A9M485, MQO_NEIM0  ;  Q9JWK3, MQO_NEIMA  ;  Q9JXD7, MQO_NEIMB  ;
DR   A1KWH2, MQO_NEIMF  ;  Q8CV11, MQO_OCEIH  ;  C6DAM1, MQO_PECCP  ;
DR   A3PBD7, MQO_PROM0  ;  A2C0M6, MQO_PROM1  ;  A8G3D1, MQO_PROM2  ;
DR   A2CBH2, MQO_PROM3  ;  A9BE38, MQO_PROM4  ;  A2BV78, MQO_PROM5  ;
DR   Q31CB9, MQO_PROM9  ;  Q7VDF8, MQO_PROMA  ;  B4F088, MQO_PROMH  ;
DR   Q7V8S6, MQO_PROMM  ;  Q7V2Q2, MQO_PROMP  ;  A2BPP7, MQO_PROMS  ;
DR   Q46GZ7, MQO_PROMT  ;  Q9S3Q5, MQO_PSEFL  ;  Q887Z4, MQO_PSESM  ;
DR   Q8XRL7, MQO_RALSO  ;  A9WQR6, MQO_RENSM  ;  C0ZY77, MQO_RHOE4  ;
DR   Q6NA55, MQO_RHOPA  ;  B3QK65, MQO_RHOPT  ;  Q0S251, MQO_RHOSR  ;
DR   A8GBY8, MQO_SERP5  ;  B2TV25, MQO_SHIB3  ;  Q31Z33, MQO_SHIBS  ;
DR   Q32I11, MQO_SHIDS  ;  Q3YZZ7, MQO_SHISS  ;  Q2NS49, MQO_SODGM  ;
DR   B2FSQ8, MQO_STRMK  ;  Q7U5L7, MQO_SYNPX  ;  A5GRE3, MQO_SYNR3  ;
DR   Q3AWX1, MQO_SYNS9  ;  Q3ALG7, MQO_SYNSC  ;  C4LEV7, MQO_TOLAT  ;
DR   Q8D1V2, MQO_WIGBR  ;  Q7MBG6, MQO_WOLSU  ;  B2I8R2, MQO_XYLF2  ;
DR   Q9PET6, MQO_XYLFA  ;  B0U4L2, MQO_XYLFM  ;  Q87AS0, MQO_XYLFT  ;
//
ID   1.1.5.5
DE   Alcohol dehydrogenase (quinone).
AN   PQQ alcohol dehydrogenase.
AN   PQQ-dependent ADH.
AN   PQQ-dependent alcohol dehydrogenase.
AN   Pyrroloquinoline quinone-dependent alcohol dehydrogenase.
AN   Quinoprotein ADH.
AN   Quinoprotein alcohol dehydrogenase.
AN   Type III ADH.
CA   Ethanol + ubiquinone = acetaldehyde + ubiquinol.
CF   Pyrroloquinoline quinone.
CC   -!- Only described in acetic acid bacteria where it is involved in acetic
CC       acid production.
CC   -!- Associated with membrane.
CC   -!- Electron acceptor is membrane ubiquinone.
CC   -!- A model structure suggests that, like all other quinoprotein alcohol
CC       dehydrogenases, the catalytic subunit has an 8-bladed 'propeller'
CC       structure, a calcium ion bound to the PQQ in the active site and an
CC       unusual disulfide ring structure in close proximity to the PQQ; the
CC       catalytic subunit also has a heme c in the C-terminal domain.
CC   -!- The enzyme has two additional subunits, one of which contains three
CC       molecules of heme c.
CC   -!- It does not require amines for activation.
CC   -!- It has a restricted substrate specificity, oxidizing a few primary
CC       alcohols (C2 to C6), but not methanol, secondary alcohols and some
CC       aldehydes.
CC   -!- It is assayed with phenazine methosulfate or with ferricyanide.
//
ID   1.1.5.6
DE   Formate dehydrogenase-N.
AN   Formate dehydrogenase N.
AN   Nitrate inducible formate dehydrogenase.
CA   Formate + a quinone = CO(2) + a quinol.
CC   -!- Formate dehydrogenase-N oxidizes formate in the periplasm,
CC       transferring electrons via the menaquinone pool in the cytoplasmic
CC       membrane to a dissimilatory nitrate reductase (EC 1.7.5.1), which
CC       transfers electrons to nitrate in the cytoplasm.
CC   -!- The system generates proton motive force under anaerobic conditions.
PR   PROSITE; PDOC00392;
//
ID   1.1.5.7
DE   Cyclic alcohol dehydrogenase (quinone).
AN   Cyclic alcohol dehydrogenase.
AN   MCAD.
CA   A cyclic alcohol + a quinone = a cyclic ketone + a quinol.
CC   -!- This enzyme oxidizes a wide variety of cyclic alcohols.
CC   -!- Some minor enzyme activity is found with aliphatic secondary alcohols
CC       and sugar alcohols, but not primary alcohols.
CC   -!- The enzyme is unable to catalyze the reverse reaction of cyclic
CC       ketones or aldehydes to cyclic alcohols.
CC   -!- This enzyme differs from EC 1.1.5.5, which shows activity with
CC       ethanol.
//
ID   1.1.5.8
DE   Quinate dehydrogenase (quinone).
AN   NAD(P)(+)-independent quinate dehydrogenase.
CA   Quinate + quinone = 3-dehydroquinate + quinol.
CF   Pyrroloquinoline quinone.
CC   -!- The enzyme is membrane-bound.
CC   -!- Does not use NAD(P)(+) as acceptor.
CC   -!- Formerly EC 1.1.99.25.
DR   Q59086, QUIA_ACIAD ;  Q9XD78, QUIA_XANCJ ;
//
ID   1.1.5.n1
DE   Quinoprotein inositol dehydrogenase.
AN   Membrane-bound quinoprotein inositol dehydrogenase.
AN   PQQ-dependent inositol dehydrogenase.
AN   QIDH.
CA   Myo-inositol + pyrroloquinoline quinone = 2,4,6/3,5-
CA   pentahydroxycyclohexanone + pyrroloquinoline quinol.
CF   Pyrroloquinoline quinone.
//
ID   1.1.98.1
DE   Alcohol dehydrogenase (azurin).
AN   QHEDH.
CA   A primary alcohol + oxidized azurin = an aldehyde + reduced azurin.
CF   Heme; Pyrroloquinoline quinone.
CC   -!- Occurs in Comamonas and Pseudomonas.
CC   -!- Does not require an amine activator.
CC   -!- Oxidizes a wide range of primary and secondary alcohols, and also
CC       aldehydes and large substrates such as sterols; methanol is not a
CC       substrate.
CC   -!- Usually assayed with phenazine methosulfate or ferricyanide.
CC   -!- Like all other quinoprotein alcohol dehydrogenases it has an 8-bladed
CC       'propeller' structure, a calcium ion bound to the PQQ in the active
CC       site and an unusual disulfide ring structure in close proximity to
CC       the PQQ.
DR   Q46444, QHED_COMTE ;
//
ID   1.1.98.2
DE   Glucose-6-phosphate dehydrogenase (coenzyme-F420).
AN   Coenzyme F420-dependent glucose-6-phosphate dehydrogenase.
AN   F420-dependent glucose-6-phosphate dehydrogenase.
CA   D-glucose 6-phosphate + oxidized coenzyme F420 = D-glucono-1,5-lactone
CA   6-phosphate + reduced coenzyme F420.
CC   -!- The enzyme is very specific for D-glucose 6-phosphate.
CC   -!- No activity with NAD(+), NADP(+), flavin adenine dinucleotide and
CC       flavin mononucleotide.
CC   -!- Formerly EC 1.1.99.34.
DR   P96253, FGD1_MYCTU ;
//
ID   1.1.99.1
DE   Choline dehydrogenase.
AN   Choline oxidase.
AN   Choline-cytochrome c reductase.
CA   Choline + acceptor = betaine aldehyde + reduced acceptor.
CF   Pyrroloquinoline quinone.
CC   -!- In many bacteria, plants and animals, the osmoprotectant betaine is
CC       synthesized using different enzymes to catalyze the conversion of (1)
CC       choline into betaine aldehyde and (2) betaine aldehyde into betaine.
CC   -!- In plants, the first reaction is catalyzed by EC 1.14.15.7 whereas in
CC       animals and many bacteria, it is catalyzed by either EC 1.1.99.1 or
CC       EC 1.1.3.17.
CC   -!- The enzyme involved in the second step, EC 1.2.1.8, appears to be the
CC       same in plants, animals and bacteria.
PR   PROSITE; PDOC00543;
DR   Q1QXE1, BETA1_CHRSD;  Q9L4K0, BETA2_CHRSD;  Q6FDF9, BETA_ACIAD ;
DR   B7GYG5, BETA_ACIB3 ;  B7I895, BETA_ACIB5 ;  B2HV79, BETA_ACIBC ;
DR   B0VST3, BETA_ACIBS ;  B0V945, BETA_ACIBY ;  B9JBA2, BETA_AGRRK ;
DR   Q8UH55, BETA_AGRT5 ;  A9M9H8, BETA_BRUC2 ;  Q8YFY2, BETA_BRUME ;
DR   A5VPA6, BETA_BRUO2 ;  B0CKN4, BETA_BRUSI ;  Q8G1Z8, BETA_BRUSU ;
DR   B1Z034, BETA_BURA4 ;  Q1BQE2, BETA_BURCA ;  B1K707, BETA_BURCC ;
DR   A0B2F7, BETA_BURCH ;  B4EHJ2, BETA_BURCJ ;  Q0B711, BETA_BURCM ;
DR   A9AMZ9, BETA_BURM1 ;  Q62CH8, BETA_BURMA ;  Q3JLL7, BETA_BURP1 ;
DR   B2JS89, BETA_BURP8 ;  B2TCJ8, BETA_BURPP ;  Q63KK7, BETA_BURPS ;
DR   Q39A44, BETA_BURS3 ;  Q2T6D0, BETA_BURTA ;  A4JJG6, BETA_BURVG ;
DR   Q13NG7, BETA_BURXL ;  A8AJN0, BETA_CITK8 ;  A7ZI50, BETA_ECO24 ;
DR   B7UJG4, BETA_ECO27 ;  B7MCD0, BETA_ECO45 ;  B7L439, BETA_ECO55 ;
DR   Q8X6C6, BETA_ECO57 ;  B5Z1R0, BETA_ECO5E ;  B7M2V5, BETA_ECO8A ;
DR   B1XE52, BETA_ECODH ;  A7ZWV4, BETA_ECOHS ;  Q0TKW1, BETA_ECOL5 ;
DR   Q8FKI9, BETA_ECOL6 ;  B1J0W6, BETA_ECOLC ;  P17444, BETA_ECOLI ;
DR   B7N8L3, BETA_ECOLU ;  B6I074, BETA_ECOSE ;  B1LIJ7, BETA_ECOSM ;
DR   Q1RFM3, BETA_ECOUT ;  A7MFA8, BETA_ENTS8 ;  Q6D6D9, BETA_ERWCT ;
DR   B5Y008, BETA_KLEP3 ;  A6T613, BETA_KLEP7 ;  A6X2G7, BETA_OCHA4 ;
DR   C6DKY4, BETA_PECCP ;  Q6LGH5, BETA_PHOPR ;  B4EX94, BETA_PROMH ;
DR   Q48CM7, BETA_PSE14 ;  A6VEI3, BETA_PSEA7 ;  B7V5R3, BETA_PSEA8 ;
DR   Q02DZ0, BETA_PSEAB ;  Q9HTJ2, BETA_PSEAE ;  Q1IG70, BETA_PSEE4 ;
DR   Q4K4K7, BETA_PSEF5 ;  C3K3D3, BETA_PSEFS ;  A4XPI5, BETA_PSEMY ;
DR   A5WA97, BETA_PSEP1 ;  Q3K5H3, BETA_PSEPF ;  B0KN19, BETA_PSEPG ;
DR   Q88CW6, BETA_PSEPK ;  Q88AE7, BETA_PSESM ;  Q4ZM63, BETA_PSEU2 ;
DR   B3PTE0, BETA_RHIE6 ;  Q2KB43, BETA_RHIEC ;  Q1MJU4, BETA_RHIL3 ;
DR   Q985M5, BETA_RHILO ;  B5ZUG2, BETA_RHILW ;  P54223, BETA_RHIME ;
DR   C3MIE4, BETA_RHISN ;  A8GBX9, BETA_SERP5 ;  Q0T7N0, BETA_SHIF8 ;
DR   A6U6Y8, BETA_SINMW ;  A7X6Z3, BETA_STAA1 ;  A6U4Z2, BETA_STAA2 ;
DR   Q2FDP9, BETA_STAA3 ;  Q2FV11, BETA_STAA8 ;  A5IW37, BETA_STAA9 ;
DR   Q2YWJ5, BETA_STAAB ;  Q5HCU1, BETA_STAAC ;  A6QK99, BETA_STAAE ;
DR   P60336, BETA_STAAM ;  P60337, BETA_STAAN ;  Q6GDJ1, BETA_STAAR ;
DR   Q6G664, BETA_STAAS ;  A8Z5A4, BETA_STAAT ;  Q8NUM0, BETA_STAAW ;
DR   Q5HL11, BETA_STAEQ ;  Q8CMY2, BETA_STAES ;  Q4L9D7, BETA_STAHJ ;
DR   Q4A0Q1, BETA_STAS1 ;  Q9X2M2, BETA_STAXY ;  B4SHV9, BETA_STRM5 ;
DR   B2FQ89, BETA_STRMK ;  A7N2P9, BETA_VIBHB ;  Q8D3K2, BETA_VIBVU ;
DR   Q7MF12, BETA_VIBVY ;  Q8PPG8, BETA_XANAC ;  Q3BXK8, BETA_XANC5 ;
DR   Q4UYN5, BETA_XANC8 ;  B0RNU9, BETA_XANCB ;  Q8P5D7, BETA_XANCP ;
DR   A7FKL6, BETA_YERP3 ;  Q1C932, BETA_YERPA ;  B2K8U4, BETA_YERPB ;
DR   Q8ZGW0, BETA_YERPE ;  Q1CFR7, BETA_YERPN ;  A4TNP2, BETA_YERPP ;
DR   Q66D54, BETA_YERPS ;  B1JSR0, BETA_YERPY ;  Q8NE62, CHDH_HUMAN ;
DR   Q8BJ64, CHDH_MOUSE ;
//
ID   1.1.99.2
DE   2-hydroxyglutarate dehydrogenase.
AN   Alpha-hydroxyglutarate dehydrogenase.
AN   Alpha-hydroxyglutarate oxidoreductase.
AN   Alpha-ketoglutarate reductase.
AN   Hydroxyglutaric dehydrogenase.
AN   L-alpha-hydroxyglutarate dehydrogenase.
CA   (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.
CF   FAD.
DR   A7MBI3, L2HDH_BOVIN;  A8X2R1, L2HDH_CAEBR;  Q9N4Z0, L2HDH_CAEEL;
DR   Q55GI5, L2HDH_DICDI;  Q9H9P8, L2HDH_HUMAN;  Q91YP0, L2HDH_MOUSE;
DR   A7SMW7, L2HDH_NEMVE;  Q5R9N7, L2HDH_PONAB;
//
ID   1.1.99.3
DE   Gluconate 2-dehydrogenase (acceptor).
CA   D-gluconate + acceptor = 2-dehydro-D-gluconate + reduced acceptor.
CF   FAD.
DR   O34214, GADH1_PECCY;  O34215, GADH2_PECCY;  O34213, GADH3_PECCY;
//
ID   1.1.99.4
DE   Dehydrogluconate dehydrogenase.
AN   Ketogluconate dehydrogenase.
CA   2-dehydro-D-gluconate + acceptor = 2,5-didehydro-D-gluconate + reduced
CA   acceptor.
CF   Flavoprotein.
//
ID   1.1.99.5
DE   Transferred entry: 1.1.5.3.
//
ID   1.1.99.6
DE   D-2-hydroxy-acid dehydrogenase.
CA   (R)-lactate + acceptor = pyruvate + reduced acceptor.
CF   FAD; Zinc.
CC   -!- Acts on a variety of (R)-2-hydroxy acids.
//
ID   1.1.99.7
DE   Lactate--malate transhydrogenase.
CA   (S)-lactate + oxaloacetate = pyruvate + malate.
CC   -!- Catalyzes hydrogen transfer from C(3) or C(4) (S)-2-hydroxy acids to
CC       2-oxo acids.
CC   -!- Contains tightly bound nicotinamide nucleotide in its active center.
CC   -!- This prosthetic group cannot be removed without denaturation of the
CC       protein.
//
ID   1.1.99.8
DE   Transferred entry: 1.1.2.7 and 1.1.2.8.
//
ID   1.1.99.9
DE   Pyridoxine 5-dehydrogenase.
AN   Pyridoxol 5-dehydrogenase.
CA   Pyridoxine + acceptor = isopyridoxal + reduced acceptor.
CF   FAD.
//
ID   1.1.99.10
DE   Glucose dehydrogenase (acceptor).
AN   Glucose dehydrogenase (Aspergillus).
CA   D-glucose + acceptor = D-glucono-1,5-lactone + reduced acceptor.
CF   FAD.
CC   -!- 2,6-dichloroindophenol can act as acceptor.
PR   PROSITE; PDOC00543;
DR   P18173, DHGL_DROME ;  P18172, DHGL_DROPS ;
//
ID   1.1.99.11
DE   Fructose 5-dehydrogenase.
AN   D-fructose dehydrogenase.
CA   D-fructose + acceptor = 5-dehydro-D-fructose + reduced acceptor.
CC   -!- 2,6-dichloroindophenol can act as acceptor.
//
ID   1.1.99.12
DE   Sorbose dehydrogenase.
CA   L-sorbose + acceptor = 5-dehydro-D-fructose + reduced acceptor.
CC   -!- 2,6-dichloroindophenol can act as acceptor.
//
ID   1.1.99.13
DE   Glucoside 3-dehydrogenase.
AN   D-aldohexopyranoside dehydrogenase.
CA   Sucrose + acceptor = 3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside +
CA   reduced acceptor.
CF   FAD.
CC   -!- The enzyme acts on D-glucose, D-galactose, D-glucosides and
CC       D-galactosides, but D-glucosides react more rapidly than
CC       D-galactosides.
//
ID   1.1.99.14
DE   Glycolate dehydrogenase.
AN   Glycolate oxidoreductase.
AN   Glycolic acid dehydrogenase.
CA   Glycolate + acceptor = glyoxylate + reduced acceptor.
CC   -!- Also acts on (R)-lactate.
CC   -!- 2,6-dichloroindophenol and phenazine methosulfate can act as
CC       acceptors.
//
ID   1.1.99.15
DE   Transferred entry: 1.5.1.20.
//
ID   1.1.99.16
DE   Transferred entry: 1.1.5.4.
//
ID   1.1.99.17
DE   Transferred entry: 1.1.5.2.
//
ID   1.1.99.18
DE   Cellobiose dehydrogenase (acceptor).
AN   CBOR.
AN   CDH.
AN   Cellobiose dehydrogenase.
AN   Cellobiose dehydrogenase (quinone).
AN   Cellobiose oxidase.
AN   Cellobiose oxidoreductase.
AN   Cellobiose-quinone oxidoreductase.
CA   Cellobiose + acceptor = cellobiono-1,5-lactone + reduced acceptor.
CF   FAD; Heme.
CC   -!- 2,6-dichloroindophenol can act as acceptor.
CC   -!- Also acts, more slowly, on cello-oligosaccharides, lactose and
CC       D-glucosyl-1,4-beta-D-mannose.
CC   -!- Includes EC 1.1.5.1, which is now known to be a proteolytic product
CC       of this enzyme.
CC   -!- The enzyme from the white rot fungus Phanerochaete chrysosporium is
CC       unusual in having two redoxin domains, one containing a flavin and
CC       the other a protoheme group.
CC   -!- It transfers reducing equivalents from cellobiose to two types of
CC       redox acceptor: two-electron oxidants, including redox dyes,
CC       benzoquinones and molecular oxygen and one-electron oxidants,
CC       including semiquinone species, Fe(2+) complexes and the model
CC       acceptor cytochrome c.
CC   -!- Formerly EC 1.1.3.25.
DR   Q01738, CDH_PHACH  ;
//
ID   1.1.99.19
DE   Transferred entry: 1.17.99.4.
//
ID   1.1.99.20
DE   Alkan-1-ol dehydrogenase (acceptor).
AN   Polyethylene glycol dehydrogenase.
CA   Primary alcohol + acceptor = aldehyde + reduced acceptor.
CF   Pyrroloquinoline quinone.
CC   -!- Acts on C(3)-C(16) linear-chain saturated primary alcohols, C(4)-C(7)
CC       aldehydes and on non-ionic surfactants containing polyethylene glycol
CC       residues, such as Tween 40 and 60, but not on methanol and only very
CC       slowly on ethanol.
CC   -!- 2,6-dichloroindophenol can act as acceptor.
//
ID   1.1.99.21
DE   D-sorbitol dehydrogenase (acceptor).
CA   D-sorbitol + acceptor = L-sorbose + reduced acceptor.
CF   FAD.
//
ID   1.1.99.22
DE   Glycerol dehydrogenase (acceptor).
CA   Glycerol + acceptor = glycerone + reduced acceptor.
CF   Pyrroloquinoline quinone.
CC   -!- Also acts, more slowly, on a number of other polyols including
CC       D-sorbitol, D-arabinitol, meso-erythritol, adonitol and propylene
CC       glycol.
DR   Q70JN9, SLDA_GLUOX ;  Q8KIL1, SLDA_GLUTH ;  Q70JP0, SLDB_GLUOX ;
DR   Q8L1D5, SLDB_GLUTH ;
//
ID   1.1.99.23
DE   Transferred entry: 1.1.2.6.
//
ID   1.1.99.24
DE   Hydroxyacid-oxoacid transhydrogenase.
CA   (1) (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-
CA   hydroxyglutarate.
CA   (2) 4-hydroxybutanoate + 2-oxoglutarate = succinic semialdehyde + (R)-2-
CA   hydroxyglutarate.
DR   Q17EN4, HOT_AEDAE  ;  Q7Q547, HOT_ANOGA  ;  A6QP15, HOT_BOVIN  ;
DR   A8WTJ7, HOT_CAEBR  ;  Q9U2M4, HOT_CAEEL  ;  Q54GJ7, HOT_DICDI  ;
DR   Q9W265, HOT_DROME  ;  Q28XT3, HOT_DROPS  ;  Q8IWW8, HOT_HUMAN  ;
DR   Q8R0N6, HOT_MOUSE  ;  Q5RF11, HOT_PONAB  ;  Q4QQW3, HOT_RAT    ;
DR   Q08B39, HOT_XENLA  ;  Q6P371, HOT_XENTR  ;
//
ID   1.1.99.25
DE   Transferred entry: 1.1.5.8.
//
ID   1.1.99.26
DE   3-hydroxycyclohexanone dehydrogenase.
CA   3-hydroxycyclohexanone + acceptor = cyclohexane-1,3-dione + reduced
CA   acceptor.
CC   -!- 2,6-dichloroindophenol and methylene blue can act as acceptors.
//
ID   1.1.99.27
DE   (R)-pantolactone dehydrogenase (flavin).
AN   (R)-pantoyllactone dehydrogenase (flavin).
AN   2-dehydropantolactone reductase (flavin).
AN   2-dehydropantoyl-lactone reductase (flavin).
CA   (R)-pantolactone + acceptor = 2-dehydropantolactone + reduced acceptor.
CF   FMN.
CC   -!- High specificity for (R)-pantolactone.
CC   -!- Phenazine methosulfate (PMS) can act as acceptor.
CC   -!- The enzyme has been studied in Nocardia asteroides and shown to be
CC       membrane-bound and induced by 1,2-propanediol.
//
ID   1.1.99.28
DE   Glucose-fructose oxidoreductase.
CA   D-glucose + D-fructose = D-gluconolactone + D-glucitol.
CC   -!- D-mannose, D-xylose, D-galactose, 2-deoxy-D-glucose and L-arabinose
CC       will function as aldose substrates, but with low affinities.
CC   -!- The ketose substrate must be in the open-chain form.
CC   -!- The apparent affinity for fructose is low, because little of the
CC       fructose substrate is in the open-chain form.
CC   -!- Xylulose and glycerone (dihydroxyacetone) will replace fructose,
CC       but they are poor substrates.
CC   -!- The enzyme from Zymomonas mobilis contains tightly bound NADP(+).
DR   Q07982, GFO_ZYMMO  ;
//
ID   1.1.99.29
DE   Pyranose dehydrogenase (acceptor).
AN   PDH.
AN   Pyranose dehydrogenase.
AN   Pyranose-quinone oxidoreductase.
AN   Quinone-dependent pyranose dehydrogenase.
CA   (1) Pyranose + acceptor = 2-dehydropyranose + reduced acceptor.
CA   (2) Pyranose + acceptor = 3-dehydropyranose + reduced acceptor.
CA   (3) Pyranose + acceptor = 2,3-dehydropyranose + reduced acceptor.
CA   (4) A pyranoside + acceptor = a 3-dehydropyranoside + reduced acceptor.
CA   (5) A pyranoside + acceptor = a 3,4-dehydropyranoside + reduced acceptor.
CF   FAD.
CC   -!- A number of aldoses and ketoses in pyranose form, as well as
CC       glycosides, gluco-oligosaccharides, sucrose and lactose can act as a
CC       donor.
CC   -!- 1,4-benzoquinone or ferricenium ion (ferrocene oxidized by removal of
CC       one electron) can serve as acceptor.
CC   -!- Unlike EC 1.1.3.10, this fungal enzyme does not interact with O(2)
CC       and exhibits extremely broad substrate tolerance with variable
CC       regioselectivity (C-3, C-2 or C-3 + C-2 or C-3 + C-4) for
CC       (di)oxidation of different sugars.
CC   -!- D-glucose is exclusively or preferentially oxidized at C-3 (depending
CC       on the enzyme source), but can also be oxidized at C-2 + C-3.
CC   -!- The enzyme also acts on 1->4-alpha- and 1->4-beta-gluco-
CC       oligosaccharides, non-reducing gluco-oligosaccharides and
CC       L-arabinose, which are not substrates of EC 1.1.3.10.
CC   -!- Sugars are oxidized in their pyranose but not in their furanose form.
//
ID   1.1.99.30
DE   2-oxo-acid reductase.
AN   (2R)-hydroxycarboxylate-viologen-oxidoreductase.
AN   2-oxoacid reductase.
AN   HVOR.
CA   A (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced
CA   acceptor.
CF   Iron-sulfur; Molybdenum cofactor.
CC   -!- Has broad substrate specificity, with 2-oxo-monocarboxylates and
CC       2-oxo-dicarboxylates acting as substrates.
CC   -!- Branching in a substrate at the C-3 position results in loss of
CC       activity.
CC   -!- The enzyme from Proteus sp. is inactivated by oxygen.
DR   Q9R4Y1, HVOR_PROVU ;
//
ID   1.1.99.31
DE   (S)-mandelate dehydrogenase.
AN   L(+)-mandelate dehydrogenase.
AN   MDH.
CA   (S)-2-hydroxy-2-phenylacetate + acceptor = 2-oxo-2-phenylacetate +
CA   reduced acceptor.
CC   -!- While all enzymes of this family oxidize the (S)-enantiomer of an
CC       alpha-hydroxy acid to an alpha-oxo acid, the ultimate oxidant
CC       (oxygen, intramolecular heme or some other acceptor) depends on the
CC       particular enzyme.
CC   -!- Transfers the electron pair from FMNH(2) to a component of the
CC       electron transport chain, most probably ubiquinone.
CC   -!- It is part of a metabolic pathway in Pseudomonads that allows these
CC       organisms to utilize mandelic acid, derivatized from the common soil
CC       metabolite amygdalin, as the sole source of carbon and energy.
CC   -!- Has a large active-site pocket and preferentially binds substrates
CC       with longer sidechains, e.g. 2-hydroxyoctanoate rather than
CC       2-hydroxybutyrate.
CC   -!- It also prefers substrates that, like (S)-mandelate, have beta
CC       unsaturation, e.g. (indol-3-yl)glycolate compared with (indol-3-
CC       yl)lactate.
CC   -!- Esters of mandelate, such as methyl (S)-mandelate, are also
CC       substrates.
PR   PROSITE; PDOC00482;
DR   P32953, CYBL_RHOGR ;  P20932, MDLB_PSEPU ;
//
ID   1.1.99.32
DE   L-sorbose 1-dehydrogenase.
AN   SDH.
CA   L-sorbose + acceptor = 1-dehydro-L-sorbose + reduced acceptor.
CC   -!- The product, 1-dehydro-L-sorbose, is an intermediate in bacterial
CC       2-keto-L-gulonic-acid formation.
CC   -!- The activity of this membrane-bound enzyme is stimulated by Fe(III)
CC       or Co(2+) but is inhibited by Cu(2+).
CC   -!- Highly specific for L-sorbose as other sugars, such as glucose,
CC       mannitol and sorbitol, are not substrates.
CC   -!- Phenazine methosulfate and DCIP can act as artificial acceptors.
PR   PROSITE; PDOC00543;
DR   Q47944, SDH_GLUOX  ;
//
ID   1.1.99.33
DE   Formate dehydrogenase (acceptor).
AN   Formate dehydrogenase H.
AN   Formate dehydrogenase O.
CA   Formate + acceptor = CO(2) + reduced acceptor.
CC   -!- Formate dehydrogenase H is a cytoplasmic enzyme that oxidizes formate
CC       without oxygen transfer, transferring electrons to a hydrogenase.
CC   -!- The two enzymes form the formate-hydrogen lyase complex.
CC   -!- The enzyme contains a selenocysteine residue.
PR   PROSITE; PDOC00392;
//
ID   1.1.99.34
DE   Transferred entry: 1.1.98.2.
//
ID   1.1.99.35
DE   Soluble quinoprotein glucose dehydrogenase.
AN   Glucose dehydrogenase (PQQ-dependent).
AN   Soluble glucose dehydrogenase.
CA   D-glucose + acceptor = D-glucono-1,5-lactone + reduced acceptor.
CC   -!- Soluble periplasmic enzyme containing PQQ as prosthetic group, bound
CC       to a calcium ion.
CC   -!- Electron acceptor is not known.
CC   -!- It is assayed with Wurster's Blue or phenazine methosulfate.
CC   -!- It has negligible sequence or structure similarity to other
CC       quinoproteins.
CC   -!- It catalyzes an exceptionally high rate of oxidation of a wide range
CC       of aldose sugars, including D-glucose, galactose, arabinose and
CC       xylose, and also the disaccharides lactose, cellobiose and maltose.
CC   -!- It has been described only in Acinetobacter calcoaceticus.
DR   P05465, DHGA_ACICA ;
//
ID   1.1.99.36
DE   NDMA-dependent alcohol dehydrogenase.
AN   Nicotinoprotein alcohol dehydrogenase.
CA   Ethanol + N,N-dimethyl-4-nitrosoaniline = acetaldehyde +
CA   4-(hydroxylamino)-N,N-dimethylaniline.
CF   Zinc.
CC   -!- Nicotinoprotein alcohol dehydrogenases are unique medium-chain
CC       dehydrogenases/reductases (MDR) alcohol dehydrogenases that have a
CC       tightly bound NAD(+)/NADH cofactor that does not dissociate during
CC       the catalytic process.
CC   -!- Instead, the cofactor is regenerated by a second substrate or
CC       electron carrier.
CC   -!- While the in vivo electron acceptor is not known, N,N-dimethyl-4-
CC       nitrosoaniline (NDMA) can serve this function in vitro.
CC   -!- The enzyme from the Gram-positive bacterium Amycolatopsis methanolica
CC       can accept many primary alcohols as substrates, including
CC       benzylalcohol.
//
ID   1.1.99.37
DE   NDMA-dependent methanol dehydrogenase.
AN   Nicotinoprotein methanol dehydrogenase.
CA   Methanol + N,N-dimethyl-4-nitrosoaniline = formaldehyde +
CA   4-(hydroxylamino)-N,N-dimethylaniline.
CF   Zinc and magnesium.
CC   -!- Nicotinoprotein methanol dehydrogenases have a tightly bound
CC       NADP+/NADPH cofactor that does not dissociate during the catalytic
CC       process.
CC   -!- Instead, the cofactor is regenerated by a second substrate or
CC       electron carrier.
CC   -!- While the in vivo electron acceptor is not known, N,N-dimethyl-4-
CC       nitrosoaniline (NDMA) can serve this function in vitro.
CC   -!- The enzyme has been detected in several Gram-positive methylotrophic
CC       bacteria, including Amycolatopsis methanolica, Rhodococcus
CC       rhodochrous and Rhodococcus erythropolis.
CC   -!- These enzymes are decameric, and possess a 5-fold symmetry.
CC   -!- Some of the enzymes can also dismutate formaldehyde to methanol and
CC       formate.
//
ID   1.2.1.1
DE   Transferred entry: 1.1.1.284 and 4.4.1.22.
//
ID   1.2.1.2
DE   Formate dehydrogenase.
CA   Formate + NAD(+) = CO(2) + NADH.
CF   Flavin; Iron-sulfur; Molybdenum.
CC   -!- The enzyme from most aerobic organisms is devoid of redox-active
CC       centers but that from the proteobacterium Methylosinus trichosporium
CC       contains iron-sulfur centers, flavin and a molybdenum center.
CC   -!- Together with EC 1.12.1.2, forms a system previously known as formate
CC       hydrogenlyase.
PR   PROSITE; PDOC00063;
PR   PROSITE; PDOC00392;
DR   Q9SXP2, FDH1_ORYSJ ;  Q08911, FDH1_YEAST ;  Q67U69, FDH2_ORYSJ ;
DR   A6ZN46, FDH2_YEAS7 ;  C8ZHD6, FDH2_YEAS8 ;  P0CF35, FDH2_YEAST ;
DR   Q934F5, FDHA_DESGI ;  P06131, FDHA_METFO ;  P61159, FDHA_METJA ;
DR   P06130, FDHB_METFO ;  Q60316, FDHB_METJA ;  Q50570, FDHB_METTF ;
DR   P07658, FDHF_ECOLI ;  Q795Y4, FDHL_BACSU ;  Q2FEI5, FDHL_STAA3 ;
DR   Q2FVV9, FDHL_STAA8 ;  Q2YYT1, FDHL_STAAB ;  Q5HDP9, FDHL_STAAC ;
DR   Q931G2, FDHL_STAAM ;  Q99RW4, FDHL_STAAN ;  Q6GEC4, FDHL_STAAR ;
DR   Q6G711, FDHL_STAAS ;  Q7A057, FDHL_STAAW ;  Q4L8G8, FDHL_STAHJ ;
DR   Q49ZN0, FDHL_STAS1 ;  Q9S7E4, FDH_ARATH  ;  O13437, FDH_CANBO  ;
DR   Q03134, FDH_EMENI  ;  Q9ZRI8, FDH_HORVU  ;  Q07103, FDH_NEUCR  ;
DR   P33677, FDH_PICAN  ;  P33160, FDH_PSESR  ;  Q07511, FDH_SOLTU  ;
DR   P24183, FDNG_ECOLI ;  P32176, FDOG_ECOLI ;  P46448, FDXG_HAEIN ;
//
ID   1.2.1.3
DE   Aldehyde dehydrogenase (NAD(+)).
CA   An aldehyde + NAD(+) + H(2)O = an acid + NADH.
CC   -!- Wide specificity, including oxidation of D-glucuronolactone to
CC       D-glucarate.
CC   -!- Formerly EC 1.1.1.70.
PR   PROSITE; PDOC00068;
DR   Q7ZVB2, A9A1A_DANRE;  Q802W2, A9A1B_DANRE;  O35945, AL1A7_MOUSE;
DR   P13601, AL1A7_RAT  ;  P52476, AL1B1_BOVIN;  P30837, AL1B1_HUMAN;
DR   Q9CZS1, AL1B1_MOUSE;  Q5R6B5, AL1B1_PONAB;  Q66HF8, AL1B1_RAT  ;
DR   Q0WSF1, AL221_ARATH;  Q9SU63, AL2B4_ARATH;  Q8S528, AL2B7_ARATH;
DR   Q56YU0, AL2C4_ARATH;  P51648, AL3A2_HUMAN;  Q60HH8, AL3A2_MACFA;
DR   P47740, AL3A2_MOUSE;  Q5RF60, AL3A2_PONAB;  P30839, AL3A2_RAT  ;
DR   Q70E96, AL3F1_ARATH;  Q70DU8, AL3H1_ARATH;  Q8W033, AL3I1_ARATH;
DR   Q2KJC9, AL7A1_BOVIN;  Q41247, AL7A1_BRANA;  P46562, AL7A1_CAEEL;
DR   P83401, AL7A1_DICDI;  P49419, AL7A1_HUMAN;  Q9ZPB7, AL7A1_MALDO;
DR   Q9DBF1, AL7A1_MOUSE;  P25795, AL7A1_PEA  ;  Q64057, AL7A1_RAT  ;
DR   Q9SYG7, AL7B4_ARATH;  Q2KJH9, AL9A1_BOVIN;  P49189, AL9A1_HUMAN;
DR   Q9JLJ2, AL9A1_MOUSE;  Q19A30, AL9A1_ORYLA;  Q29228, AL9A1_PIG  ;
DR   Q5R8A4, AL9A1_PONAB;  Q9JLJ3, AL9A1_RAT  ;  Q2FF06, ALD1_STAA3 ;
DR   Q2FWD6, ALD1_STAA8 ;  Q2YUN1, ALD1_STAAB ;  Q5HE78, ALD1_STAAC ;
DR   Q99SD6, ALD1_STAAM ;  Q7A4D8, ALD1_STAAN ;  Q6GEV3, ALD1_STAAR ;
DR   Q6G7I8, ALD1_STAAS ;  Q8NVG4, ALD1_STAAW ;  Q5HMA0, ALD1_STAEQ ;
DR   Q8CNI5, ALD1_STAES ;  Q4L803, ALD1_STAHJ ;  Q49Z69, ALD1_STAS1 ;
DR   Q2FK94, ALDA_STAA3 ;  Q2G1J0, ALDA_STAA8 ;  Q2YV11, ALDA_STAAB ;
DR   Q5HJK3, ALDA_STAAC ;  Q99X54, ALDA_STAAM ;  Q7A825, ALDA_STAAN ;
DR   Q6GKD8, ALDA_STAAR ;  Q6GCV9, ALDA_STAAS ;  Q7A1Y7, ALDA_STAAW ;
DR   Q5HLA3, ALDA_STAEQ ;  Q8CN24, ALDA_STAES ;  Q4L919, ALDA_STAHJ ;
DR   P42236, ALDH1_BACSU;  Q28399, ALDH1_ELEED;  P30840, ALDH1_ENTHI;
DR   Q29490, ALDH1_MACPR;  P39616, ALDH2_BACSU;  P20000, ALDH2_BOVIN;
DR   P45959, ALDH2_GEOSE;  P12762, ALDH2_HORSE;  P05091, ALDH2_HUMAN;
DR   Q25417, ALDH2_LEITA;  Q29491, ALDH2_MACPR;  P81178, ALDH2_MESAU;
DR   P47738, ALDH2_MOUSE;  Q2XQV4, ALDH2_PIG  ;  Q5RF00, ALDH2_PONAB;
DR   P11884, ALDH2_RAT  ;  P46329, ALDH3_BACSU;  O34660, ALDH4_BACSU;
DR   P46367, ALDH4_YEAST;  O06478, ALDH5_BACSU;  A6ZR27, ALDH5_YEAS7;
DR   P40047, ALDH5_YEAST;  P54115, ALDH6_YEAST;  Q94688, ALDH9_POLMI;
DR   P22281, ALDHX_YEASX;  P32872, ALDHY_YEASX;  O74187, ALDH_AGABI ;
DR   P42041, ALDH_ALTAL ;  P41751, ALDH_ASPNG ;  Q8VXQ2, ALDH_CRAPL ;
DR   P40108, ALDH_DAVTA ;  Q9RYG9, ALDH_DEIRA ;  P08157, ALDH_EMENI ;
DR   Q27640, ALDH_ENCBU ;  Q40255, ALDH_LINUS ;  P63938, ALDH_MYCBO ;
DR   P63937, ALDH_MYCTU ;  P12693, ALDH_PSEOL ;  P33008, ALDH_PSESP ;
DR   Q9ZA11, ALDH_RHORT ;  Q9RJZ6, ALDH_STRCO ;  A5F3A7, ALDH_VIBC3 ;
DR   P0C6D7, ALDH_VIBCH ;  P56533, BADH_GADCA ;  P46368, DHA2_CUPNH ;
DR   P46369, THCA_RHOER ;
//
ID   1.2.1.4
DE   Aldehyde dehydrogenase (NADP(+)).
CA   An aldehyde + NADP(+) + H(2)O = an acid + NADPH.
DR   A6ZR27, ALDH5_YEAS7;  P40047, ALDH5_YEAST;  Q56694, ALDH_VIBHA ;
//
ID   1.2.1.5
DE   Aldehyde dehydrogenase (NAD(P)(+)).
CA   An aldehyde + NAD(P)(+) + H(2)O = an acid + NAD(P)H.
PR   PROSITE; PDOC00068;
DR   P47895, AL1A3_HUMAN;  Q9JHW9, AL1A3_MOUSE;  Q8K4D8, AL1A3_RAT  ;
DR   P30907, AL3A1_BOVIN;  A3RF36, AL3A1_CANFA;  P30838, AL3A1_HUMAN;
DR   P47739, AL3A1_MOUSE;  P11883, AL3A1_RAT  ;  Q1JPA0, AL3B1_BOVIN;
DR   P43353, AL3B1_HUMAN;  Q80VQ0, AL3B1_MOUSE;  Q5XI42, AL3B1_RAT  ;
DR   P48448, AL3B2_HUMAN;  P47771, ALDH2_YEAST;  Q54DG1, ALDH3_DICDI;
DR   P54114, ALDH3_YEAST;  P42329, ALDH_GEOSE ;  P23883, PUUC_ECOLI ;
//
ID   1.2.1.6
DE   Deleted entry.
//
ID   1.2.1.7
DE   Benzaldehyde dehydrogenase (NADP(+)).
CA   Benzaldehyde + NADP(+) + H(2)O = benzoate + NADPH.
//
ID   1.2.1.8
DE   Betaine-aldehyde dehydrogenase.
AN   BADH.
AN   Betaine aldehyde dehydrogenase.
AN   Betaine aldehyde oxidase.
CA   Betaine aldehyde + NAD(+) + H(2)O = betaine + NADH.
CC   -!- In many bacteria, plants and animals, the osmoprotectant betaine is
CC       synthesized in two steps: (1) choline to betaine aldehyde and (2)
CC       betaine aldehyde to betaine.
CC   -!- This enzyme is involved in the second step and appears to be the same
CC       in plants, animals and bacteria.
CC   -!- In contrast, different enzymes are involved in the first reaction.
CC   -!- In plants, this reaction is catalyzed by EC 1.14.15.7, whereas in
CC       animals and many bacteria, it is catalyzed by either membrane-bound
CC       EC 1.1.99.1 or soluble EC 1.1.3.17.
CC   -!- In some bacteria, betaine is synthesized from glycine through the
CC       actions of EC 2.1.1.156 and EC 2.1.1.157.
PR   PROSITE; PDOC00068;
DR   Q2KJC9, AL7A1_BOVIN;  P49419, AL7A1_HUMAN;  Q9DBF1, AL7A1_MOUSE;
DR   Q64057, AL7A1_RAT  ;  Q9S795, BADH1_ARATH;  Q9STS1, BADH2_ARATH;
DR   O04895, BADH_AMAHP ;  P42757, BADH_ATRHO ;  P28237, BADH_BETVU ;
DR   P56533, BADH_GADCA ;  Q40024, BADH_HORVU ;  O24174, BADH_ORYSJ ;
DR   O59808, BADH_SCHPO ;  P17202, BADH_SPIOL ;  P54222, BETB1_RHIME;
DR   Q92YD2, BETB2_RHIME;  Q6FDF8, BETB_ACIAD ;  B7GYG4, BETB_ACIB3 ;
DR   B7I896, BETB_ACIB5 ;  B2HV80, BETB_ACIBC ;  B0VST2, BETB_ACIBS ;
DR   A3M365, BETB_ACIBT ;  B0V944, BETB_ACIBY ;  B9JBA3, BETB_AGRRK ;
DR   Q8UH56, BETB_AGRT5 ;  P71016, BETB_BACSU ;  B2SA42, BETB_BRUA1 ;
DR   Q2YMP8, BETB_BRUA2 ;  Q57EI0, BETB_BRUAB ;  A9M9H7, BETB_BRUC2 ;
DR   C0RHQ3, BETB_BRUMB ;  Q8YFY0, BETB_BRUME ;  A5VPA5, BETB_BRUO2 ;
DR   B0CKN3, BETB_BRUSI ;  Q8G1Z9, BETB_BRUSU ;  B1Z033, BETB_BURA4 ;
DR   Q1BQE1, BETB_BURCA ;  B1K708, BETB_BURCC ;  A0B2F6, BETB_BURCH ;
DR   B4EHJ1, BETB_BURCJ ;  Q0B712, BETB_BURCM ;  A9AN00, BETB_BURM1 ;
DR   A3MEC6, BETB_BURM7 ;  A2RWD6, BETB_BURM9 ;  Q62CH7, BETB_BURMA ;
DR   A1UVS4, BETB_BURMS ;  A3P6B0, BETB_BURP0 ;  Q3JLL8, BETB_BURP1 ;
DR   A3NKP8, BETB_BURP6 ;  B2JS88, BETB_BURP8 ;  B2TCJ9, BETB_BURPP ;
DR   Q63KK8, BETB_BURPS ;  Q39A43, BETB_BURS3 ;  A4JJG5, BETB_BURVG ;
DR   Q13NG6, BETB_BURXL ;  Q9L4K1, BETB_CHRSD ;  A7ZI51, BETB_ECO24 ;
DR   B7UJG5, BETB_ECO27 ;  B7MCD1, BETB_ECO45 ;  B7L441, BETB_ECO55 ;
DR   Q7AH91, BETB_ECO57 ;  B5Z1R1, BETB_ECO5E ;  B7NK50, BETB_ECO7I ;
DR   B7M2V6, BETB_ECO8A ;  B1XET7, BETB_ECODH ;  A7ZWV5, BETB_ECOHS ;
DR   Q0TKW0, BETB_ECOL5 ;  Q8FKI8, BETB_ECOL6 ;  B1J0W5, BETB_ECOLC ;
DR   P17445, BETB_ECOLI ;  B7N8L4, BETB_ECOLU ;  B6I075, BETB_ECOSE ;
DR   B1LIJ8, BETB_ECOSM ;  Q6D6E0, BETB_ERWCT ;  B5Y007, BETB_KLEP3 ;
DR   A6W2P7, BETB_MARMS ;  A6X2G8, BETB_OCHA4 ;  C6DKY5, BETB_PECCP ;
DR   Q48CM6, BETB_PSE14 ;  A6VEI4, BETB_PSEA7 ;  B7V5R4, BETB_PSEA8 ;
DR   Q02DY9, BETB_PSEAB ;  Q9HTJ1, BETB_PSEAE ;  Q1IG69, BETB_PSEE4 ;
DR   Q4K4K8, BETB_PSEF5 ;  C3K3D2, BETB_PSEFS ;  A4XPI6, BETB_PSEMY ;
DR   A5WA96, BETB_PSEP1 ;  Q3K5H4, BETB_PSEPF ;  B0KN18, BETB_PSEPG ;
DR   Q88CW7, BETB_PSEPK ;  B1J2K9, BETB_PSEPW ;  Q88AE9, BETB_PSESM ;
DR   Q4ZM62, BETB_PSEU2 ;  A4VKC2, BETB_PSEU5 ;  B3PTE1, BETB_RHIE6 ;
DR   Q2KB42, BETB_RHIEC ;  Q1MJU3, BETB_RHIL3 ;  Q985M6, BETB_RHILO ;
DR   B5ZUG3, BETB_RHILW ;  C3MIE5, BETB_RHISN ;  A3PI00, BETB_RHOS1 ;
DR   Q3J4E9, BETB_RHOS4 ;  A4WUY6, BETB_RHOS5 ;  B9KNS6, BETB_RHOSK ;
DR   A8GBX8, BETB_SERP5 ;  Q0T7M9, BETB_SHIF8 ;  A6U6Y9, BETB_SINMW ;
DR   B4SHW0, BETB_STRM5 ;  B2FQ90, BETB_STRMK ;  A7N2Q0, BETB_VIBHB ;
DR   Q87H52, BETB_VIBPA ;  B7VQ28, BETB_VIBSL ;  Q8D3K3, BETB_VIBVU ;
DR   Q7MF13, BETB_VIBVY ;  Q8PPG7, BETB_XANAC ;  Q3BXK7, BETB_XANC5 ;
DR   Q4UYN4, BETB_XANC8 ;  B0RNV0, BETB_XANCB ;  Q8P5D8, BETB_XANCP ;
DR   A7FKL5, BETB_YERP3 ;  Q1C931, BETB_YERPA ;  B2K8U5, BETB_YERPB ;
DR   Q8ZGV9, BETB_YERPE ;  Q1CFR8, BETB_YERPN ;  A4TNP1, BETB_YERPP ;
DR   Q66D53, BETB_YERPS ;  B1JSQ9, BETB_YERPY ;
//
ID   1.2.1.9
DE   Glyceraldehyde-3-phosphate dehydrogenase (NADP(+)).
AN   Triosephosphate dehydrogenase.
CA   D-glyceraldehyde 3-phosphate + NADP(+) + H(2)O = 3-phospho-D-glycerate +
CA   NADPH.
PR   PROSITE; PDOC00068;
DR   Q9SNX8, GAPN_APIGR ;  Q1WIQ6, GAPN_ARATH ;  Q43272, GAPN_MAIZE ;
DR   P93338, GAPN_NICPL ;  P81406, GAPN_PEA   ;  Q8VXQ7, GAPN_SCEVA ;
DR   Q3C1A6, GAPN_STREI ;  Q59931, GAPN_STRMU ;  Q8LK61, GAPN_WHEAT ;
//
ID   1.2.1.10
DE   Acetaldehyde dehydrogenase (acetylating).
AN   Acylating acetaldehyde dehydrogenase.
AN   Aldehyde dehydrogenase (acylating).
CA   Acetaldehyde + CoA + NAD(+) = acetyl-CoA + NADH.
CC   -!- Also acts, more slowly, on glycolaldehyde, propanal and butanal.
CC   -!- In Pseudomonas species, this enzyme forms part of a bifunctional
CC       enzyme with EC 4.1.3.39.
CC   -!- It is the final enzyme in the meta-cleavage pathway for the
CC       degradation of phenols, methylphenols and catechol, converting the
CC       acetaldehyde produced by EC 4.1.3.39 into acetyl-CoA.
CC   -!- NADP(+) can replace NAD(+) but the rate of reaction is much slower.
PR   PROSITE; PDOC00059;
DR   A1K6L8, ACDH1_AZOSB;  C1DMT1, ACDH1_AZOVD;  B4EK77, ACDH1_BURCJ;
DR   B2JLM7, ACDH1_BURP8;  Q397R0, ACDH1_BURS3;  A4JPX8, ACDH1_BURVG;
DR   Q143P8, ACDH1_BURXL;  Q83VZ4, ACDH1_COMTE;  Q0K3S6, ACDH1_CUPNH;
DR   Q47HL9, ACDH1_DECAR;  A8LAA2, ACDH1_FRASN;  A2SI34, ACDH1_METPP;
DR   B1MH39, ACDH1_MYCA9;  B2HGH0, ACDH1_MYCMM;  A0QZU1, ACDH1_MYCS2;
DR   A3Q4B8, ACDH1_MYCSJ;  A1UM81, ACDH1_MYCSK;  Q1B2X0, ACDH1_MYCSS;
DR   A0PR19, ACDH1_MYCUA;  A1T2N5, ACDH1_MYCVP;  Q5Z2N3, ACDH1_NOCFA;
DR   A1SH78, ACDH1_NOCSJ;  A4XF36, ACDH1_NOVAD;  A5W4E5, ACDH1_PSEP1;
DR   Q4F8I0, ACDH1_PSEPS;  B1J6Y6, ACDH1_PSEPW;  Q1LNS3, ACDH1_RALME;
DR   C0ZPX0, ACDH1_RHOE4;  C1B7L1, ACDH1_RHOOB;  Q0SJD4, ACDH1_RHOSR;
DR   A8M1N1, ACDH1_SALAI;  A5V6T7, ACDH1_SPHWW;  A1K6Y5, ACDH2_AZOSB;
DR   C1DRI9, ACDH2_AZOVD;  B4EFI8, ACDH2_BURCJ;  B2JQV9, ACDH2_BURP8;
DR   Q396N9, ACDH2_BURS3;  A4JW24, ACDH2_BURVG;  Q13VU2, ACDH2_BURXL;
DR   Q9RHN2, ACDH2_COMTE;  Q0K3N1, ACDH2_CUPNH;  Q47GC7, ACDH2_DECAR;
DR   A8LEP9, ACDH2_FRASN;  A2SL36, ACDH2_METPP;  B1MJT8, ACDH2_MYCA9;
DR   B2HI26, ACDH2_MYCMM;  A0R4S7, ACDH2_MYCS2;  A3Q6N0, ACDH2_MYCSJ;
DR   A1UQA0, ACDH2_MYCSK;  Q1B0P7, ACDH2_MYCSS;  A0PUX3, ACDH2_MYCUA;
DR   A1TDB8, ACDH2_MYCVP;  Q5YV94, ACDH2_NOCFA;  A1SIM4, ACDH2_NOCSJ;
DR   A4XDT7, ACDH2_NOVAD;  A5W4F9, ACDH2_PSEP1;  Q52039, ACDH2_PSEPS;
DR   B1J6Y2, ACDH2_PSEPW;  Q1LCQ9, ACDH2_RALME;  C0ZU49, ACDH2_RHOE4;
DR   C1B8H9, ACDH2_RHOOB;  Q0S9X0, ACDH2_RHOSR;  A8M6W7, ACDH2_SALAI;
DR   C1DN56, ACDH3_AZOVD;  Q390P5, ACDH3_BURS3;  Q13QH7, ACDH3_BURXL;
DR   Q9S153, ACDH3_COMTE;  Q47B12, ACDH3_DECAR;  A1TFQ6, ACDH3_MYCVP;
DR   Q5YUH5, ACDH3_NOCFA;  C1BAJ3, ACDH3_RHOOB;  Q0S816, ACDH3_RHOSR;
DR   A5VGU5, ACDH3_SPHWW;  C1DF11, ACDH4_AZOVD;  Q39LH7, ACDH4_BURS3;
DR   Q79AF6, ACDH4_BURXL;  Q479G9, ACDH4_DECAR;  C1AVG3, ACDH4_RHOOB;
DR   Q0S4F9, ACDH4_RHOSR;  Q479E6, ACDH5_DECAR;  C1AYB3, ACDH5_RHOOB;
DR   Q0S005, ACDH5_RHOSR;  C1BE29, ACDH6_RHOOB;  Q0RXC4, ACDH6_RHOSR;
DR   Q0RWM7, ACDH7_RHOSR;  A1W2K2, ACDH_ACISJ ;  B9JML7, ACDH_AGRRK ;
DR   Q0A5T6, ACDH_ALHEH ;  A0RD69, ACDH_BACAH ;  Q739I5, ACDH_BACC1 ;
DR   C1ERL6, ACDH_BACC3 ;  Q764S1, ACDH_BACPJ ;  Q2KXU8, ACDH_BORA1 ;
DR   C0ZDU5, ACDH_BREBN ;  Q2VLC6, ACDH_BURCE ;  A3P826, ACDH_BURP0 ;
DR   Q3JK54, ACDH_BURP1 ;  A3NML3, ACDH_BURP6 ;  B2T2S1, ACDH_BURPP ;
DR   Q63JB0, ACDH_BURPS ;  Q2T7T0, ACDH_BURTA ;  Q3ACM1, ACDH_CARHZ ;
DR   A9W9U2, ACDH_CHLAA ;  B8GBV4, ACDH_CHLAD ;  B9LCM0, ACDH_CHLSY ;
DR   Q46NW7, ACDH_CUPPJ ;  B2AIJ6, ACDH_CUPTR ;  B8G186, ACDH_DESHD ;
DR   A7ZI98, ACDH_ECO24 ;  B7L507, ACDH_ECO55 ;  Q8X5J9, ACDH_ECO57 ;
DR   B5Z2Q6, ACDH_ECO5E ;  B7NK04, ACDH_ECO7I ;  B7MPB8, ACDH_ECO81 ;
DR   B7M2Z9, ACDH_ECO8A ;  C4ZTB5, ACDH_ECOBW ;  A7ZWZ8, ACDH_ECOHS ;
DR   B1J0S8, ACDH_ECOLC ;  P77580, ACDH_ECOLI ;  B7N8Q8, ACDH_ECOLU ;
DR   B6HZX7, ACDH_ECOSE ;  B1LIN6, ACDH_ECOSM ;  Q6D797, ACDH_ERWCT ;
DR   B0VXM6, ACDH_GEOSE ;  A4IT43, ACDH_GEOTN ;  B5XQJ3, ACDH_KLEP3 ;
DR   A6TAC5, ACDH_KLEP7 ;  B1Y2E6, ACDH_LEPCP ;  A6W1X2, ACDH_MARMS ;
DR   B8ESV1, ACDH_METSB ;  Q2RHL2, ACDH_MOOTA ;  A0QAG8, ACDH_MYCA1 ;
DR   Q7TTR4, ACDH_MYCBO ;  A1KPM0, ACDH_MYCBP ;  C1AHZ3, ACDH_MYCBT ;
DR   A4T7U3, ACDH_MYCGI ;  Q743Q9, ACDH_MYCPA ;  A5U8K9, ACDH_MYCTA ;
DR   P71866, ACDH_MYCTU ;  A5D522, ACDH_PELTS ;  A1VUV2, ACDH_POLNA ;
DR   Q120P0, ACDH_POLSJ ;  Q3IEN6, ACDH_PSEHT ;  Q49KG0, ACDH_PSEPU ;
DR   Q9KWS1, ACDH_PSESP ;  Q9ZI57, ACDH_PSEST ;  Q52060, ACDH_PSEUF ;
DR   B2UJF2, ACDH_RALPJ ;  Q8XRG0, ACDH_RALSO ;  Q221U6, ACDH_RHOFD ;
DR   A7NLU3, ACDH_ROSCS ;  A5UWE5, ACDH_ROSS1 ;  A4XAK8, ACDH_SALTO ;
DR   B0TTT0, ACDH_SHEHH ;  A8H4F0, ACDH_SHEPA ;  B1KJL0, ACDH_SHEWM ;
DR   Q3Z555, ACDH_SHISS ;  O85978, ACDH_SPHAR ;  A2TC44, ACDH_SPHYA ;
DR   Q0PHY0, ACDH_SPIAU ;  B1VRH6, ACDH_STRGG ;  B9L2J1, ACDH_THERP ;
DR   Q53WH9, ACDH_THET8 ;  A1WLL3, ACDH_VEREI ;  A7IDU5, ACDH_XANP2 ;
DR   Q24803, ADH2_ENTHI ;  P33744, ADHE_CLOAB ;  P0A9Q8, ADHE_ECO57 ;
DR   P0A9Q7, ADHE_ECOLI ;
//
ID   1.2.1.11
DE   Aspartate-semialdehyde dehydrogenase.
AN   ASA dehydrogenase.
AN   Aspartic semialdehyde dehydrogenase.
AN   L-aspartate-beta-semialdehyde dehydrogenase.
CA   L-aspartate 4-semialdehyde + phosphate + NADP(+) = L-4-aspartyl phosphate
CA   + NADPH.
PR   PROSITE; PDOC00847;
DR   Q9KQG2, DHAS1_VIBCH;  P23247, DHAS2_VIBCH;  Q44151, DHAS_ACTPL ;
DR   O67716, DHAS_AQUAE ;  O28766, DHAS_ARCFU ;  P96198, DHAS_AZOVI ;
DR   Q04797, DHAS_BACSU ;  P41399, DHAS_BORPE ;  P57523, DHAS_BUCAI ;
DR   Q8K9B5, DHAS_BUCAP ;  Q89AB8, DHAS_BUCBP ;  Q59291, DHAS_CAMJE ;
DR   P41400, DHAS_CORFL ;  P0C1D8, DHAS_CORGL ;  P0C1D9, DHAS_CORML ;
DR   P0A9R0, DHAS_ECO57 ;  Q8FCR6, DHAS_ECOL6 ;  P0A9Q9, DHAS_ECOLI ;
DR   P44801, DHAS_HAEIN ;  Q9ZK28, DHAS_HELPJ ;  O25801, DHAS_HELPY ;
DR   O31219, DHAS_LEGPN ;  Q75FC8, DHAS_LEPIC ;  P41394, DHAS_LEPIN ;
DR   Q57658, DHAS_METJA ;  O26890, DHAS_METTH ;  P0A543, DHAS_MYCBO ;
DR   P41404, DHAS_MYCSM ;  P0A542, DHAS_MYCTU ;  P57008, DHAS_NEIMA ;
DR   P30903, DHAS_NEIMB ;  P49420, DHAS_PROMA ;  Q51344, DHAS_PSEAE ;
DR   Q1RIB3, DHAS_RICBR ;  Q92IJ0, DHAS_RICCN ;  Q4UM57, DHAS_RICFE ;
DR   Q9ZDL2, DHAS_RICPR ;  Q68X56, DHAS_RICTY ;  P0A1F9, DHAS_SALTI ;
DR   P0A1F8, DHAS_SALTY ;  P78780, DHAS_SCHPO ;  Q56732, DHAS_SHESP ;
DR   Q56734, DHAS_SHEVD ;  P0A9R1, DHAS_SHIFL ;  Q53612, DHAS_STRAK ;
DR   P10539, DHAS_STRMU ;  Q55512, DHAS_SYNY3 ;  Q60080, DHAS_VIBMI ;
DR   P13663, DHAS_YEAST ;
//
ID   1.2.1.12
DE   Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).
AN   GAPDH.
AN   NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
AN   Triosephosphate dehydrogenase.
CA   D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl
CA   phosphate + NADH.
CC   -!- Also acts very slowly on D-glyceraldehyde and some other aldehydes.
CC   -!- Thiols can replace phosphate.
PR   PROSITE; PDOC00069;
DR   P32635, G3P1_AGABI ;  P34916, G3P1_ANAVT ;  Q4MQ58, G3P1_BACCE ;
DR   P09124, G3P1_BACSU ;  P04970, G3P1_CAEEL ;  Q6FPW3, G3P1_CANGA ;
DR   P07486, G3P1_DROME ;  P0A9B4, G3P1_ECO57 ;  P0A9B3, G3P1_ECOL6 ;
DR   P0A9B2, G3P1_ECOLI ;  B7LQ20, G3P1_ESCF3 ;  P0C8Z1, G3P1_ESCFE ;
DR   P24751, G3P1_ESCVU ;  P53429, G3P1_GIAIN ;  O16027, G3P1_GLORO ;
DR   P80534, G3P1_JACOR ;  P17819, G3P1_KLULA ;  P84998, G3P1_KLUMA ;
DR   P80506, G3P1_NOSS1 ;  Q9C136, G3P1_RHIRA ;  P0A1P1, G3P1_SALTI ;
DR   P0A1P0, G3P1_SALTY ;  P78958, G3P1_SCHPO ;  P0A9B5, G3P1_SHIFL ;
DR   Q5HHP5, G3P1_STAAC ;  P0A036, G3P1_STAAM ;  P99136, G3P1_STAAN ;
DR   Q6GIL8, G3P1_STAAR ;  Q6GB58, G3P1_STAAS ;  P0A038, G3P1_STAAU ;
DR   P0A037, G3P1_STAAW ;  Q5HQV4, G3P1_STAEQ ;  Q8CPY5, G3P1_STAES ;
DR   P49433, G3P1_SYNY3 ;  P17729, G3P1_TRIKO ;  P00360, G3P1_YEAST ;
DR   P32636, G3P2_AGABI ;  P34917, G3P2_ANAVT ;  P83077, G3P2_BACCE ;
DR   P32809, G3P2_CAEBR ;  P17329, G3P2_CAEEL ;  Q6FSM4, G3P2_CANGA ;
DR   P07487, G3P2_DROME ;  O44104, G3P2_DROPS ;  O44105, G3P2_DROSU ;
DR   P80447, G3P2_JACOR ;  Q6CX23, G3P2_KLULA ;  Q01077, G3P2_KLUMA ;
DR   P58554, G3P2_NOSS1 ;  Q96UF2, G3P2_RHIRA ;  P29272, G3P2_RHOSH ;
DR   O43026, G3P2_SCHPO ;  Q5HF86, G3P2_STAAC ;  P64180, G3P2_STAAM ;
DR   P99067, G3P2_STAAN ;  Q6GG19, G3P2_STAAR ;  Q6G8N9, G3P2_STAAS ;
DR   P64181, G3P2_STAAW ;  Q5HNL7, G3P2_STAEQ ;  Q8CNY0, G3P2_STAES ;
DR   P17730, G3P2_TRIKO ;  P00358, G3P2_YEAST ;  P34918, G3P3_ANAVT ;
DR   P32810, G3P3_CAEBR ;  P17330, G3P3_CAEEL ;  P58072, G3P3_ECO57 ;
DR   P33898, G3P3_ECOLI ;  P84999, G3P3_KLUMA ;  P58559, G3P3_NOSS1 ;
DR   Q96UF1, G3P3_RHIRA ;  P00359, G3P3_YEAST ;  P17331, G3P4_CAEEL ;
DR   P25861, G3PC_ANTMA ;  P25858, G3PC_ARATH ;  P49644, G3PC_CHLRE ;
DR   P34920, G3PC_CHOCR ;  Q42671, G3PC_CRAPL ;  P50321, G3PC_CUPNH ;
DR   P34921, G3PC_DIACA ;  Q39769, G3PC_GINBI ;  P54270, G3PC_GRAVE ;
DR   P08477, G3PC_HORVU ;  Q01558, G3PC_LEIME ;  P26518, G3PC_MAGLI ;
DR   P08735, G3PC_MAIZE ;  P17878, G3PC_MESCR ;  A2YQT7, G3PC_ORYSI ;
DR   Q0J8A4, G3PC_ORYSJ ;  P34922, G3PC_PEA   ;  P26519, G3PC_PETCR ;
DR   P26520, G3PC_PETHY ;  P34923, G3PC_PHYPA ;  P34924, G3PC_PINSY ;
DR   P85954, G3PC_PSEMZ ;  P26521, G3PC_RANAC ;  Q8VXQ8, G3PC_SCEVA ;
DR   P04796, G3PC_SINAL ;  Q41595, G3PC_TAXBA ;  P09094, G3PC_TOBAC ;
DR   P10097, G3PC_TRYBB ;  Q09054, G3PD_MAIZE ;  Q43247, G3PE_MAIZE ;
DR   O96423, G3PG_CRIFA ;  Q27890, G3PG_LEIME ;  P22512, G3PG_TRYBB ;
DR   P22513, G3PG_TRYCR ;  P50322, G3PP_CUPNH ;  Q2KJE5, G3PT_BOVIN ;
DR   Q5MJ86, G3PT_DANRE ;  O14556, G3PT_HUMAN ;  Q4R3T1, G3PT_MACFA ;
DR   P86211, G3PT_MESAU ;  Q64467, G3PT_MOUSE ;  Q9ESV6, G3PT_RAT   ;
DR   P26517, G3PX_HORVU ;  Q9HFX1, G3P_AJECA  ;  P55071, G3P_AMAMU  ;
DR   O67161, G3P_AQUAE  ;  Q757I2, G3P_ASHGO  ;  Q12552, G3P_ASPNG  ;
DR   Q9HGY7, G3P_ASPOR  ;  P34783, G3P_ATRNU  ;  P15115, G3P_BACCO  ;
DR   Q59199, G3P_BACFR  ;  P23722, G3P_BACMD  ;  Q00301, G3P_BOLED  ;
DR   P46795, G3P_BORBU  ;  P46796, G3P_BORHE  ;  P10096, G3P_BOVIN  ;
DR   P48812, G3P_BRUMA  ;  P57384, G3P_BUCAI  ;  Q07234, G3P_BUCAP  ;
DR   Q89AK1, G3P_BUCBP  ;  Q92211, G3P_CANAL  ;  Q28259, G3P_CANFA  ;
DR   P70685, G3P_CAVPO  ;  P00356, G3P_CHICK  ;  Q9PJN6, G3P_CHLMU  ;
DR   Q9Z7T0, G3P_CHLPN  ;  B0B879, G3P_CHLT2  ;  P0CE13, G3P_CHLTR  ;
DR   P24748, G3P_CITFR  ;  Q00584, G3P_CLAPU  ;  O52631, G3P_CLOAB  ;
DR   Q59309, G3P_CLOPA  ;  P29497, G3P_COCHE  ;  Q1DTF9, G3P_COCIM  ;
DR   Q8J1H3, G3P_COCP7  ;  P35143, G3P_COLGL  ;  O57479, G3P_COLLI  ;
DR   P54117, G3P_COLLN  ;  Q01651, G3P_CORGL  ;  Q05025, G3P_COTJA  ;
DR   P17244, G3P_CRIGR  ;  Q9Y796, G3P_CRYCU  ;  P0CN75, G3P_CRYNB  ;
DR   P0CN74, G3P_CRYNJ  ;  P19089, G3P_CRYPA  ;  P28844, G3P_CURLU  ;
DR   Q5XJ10, G3P_DANRE  ;  Q6BMK0, G3P_DEBHA  ;  Q94469, G3P_DICDI  ;
DR   Q01597, G3P_DROHY  ;  Q27652, G3P_ECHMU  ;  P20445, G3P_EMENI  ;
DR   P24163, G3P_ENTAE  ;  Q00640, G3P_ERYGR  ;  P24749, G3P_ESCBL  ;
DR   P24750, G3P_ESCHE  ;  Q9N2D5, G3P_FELCA  ;  P00362, G3P_GEOSE  ;
DR   Q4U3L0, G3P_GLOMM  ;  P44304, G3P_HAEIN  ;  Q9ZKT0, G3P_HELPJ  ;
DR   P55971, G3P_HELPY  ;  P00357, G3P_HOMAM  ;  P04406, G3P_HUMAN  ;
DR   P24164, G3P_KLEPN  ;  O32755, G3P_LACDE  ;  P55070, G3P_LACDT  ;
DR   P52987, G3P_LACLA  ;  Q9UR38, G3P_LENED  ;  Q92243, G3P_LYOSH  ;
DR   Q9N655, G3P_MASBA  ;  O57672, G3P_MELGA  ;  P51640, G3P_MESAU  ;
DR   P53430, G3P_MONPU  ;  P16858, G3P_MOUSE  ;  A3FKF7, G3P_MUSPF  ;
DR   P94915, G3P_MYCAV  ;  P64179, G3P_MYCBO  ;  P47543, G3P_MYCGE  ;
DR   P46713, G3P_MYCLE  ;  P75358, G3P_MYCPN  ;  A0QWW2, G3P_MYCS2  ;
DR   P64178, G3P_MYCTU  ;  P83601, G3P_NAEFO  ;  P54118, G3P_NEUCR  ;
DR   Q8TFJ2, G3P_OMPOL  ;  O42259, G3P_ONCMY  ;  O01360, G3P_ONCVO  ;
DR   P56649, G3P_PANVR  ;  Q8X1X3, G3P_PARBA  ;  Q5R2J2, G3P_PELSI  ;
DR   Q01982, G3P_PHACH  ;  Q9P8C0, G3P_PHANO  ;  O13507, G3P_PHARH  ;
DR   P26988, G3P_PHYIN  ;  O59841, G3P_PICAD  ;  Q92263, G3P_PICPA  ;
DR   P00355, G3P_PIG    ;  Q9UW96, G3P_PLESA  ;  P32637, G3P_PODAS  ;
DR   Q5RAB4, G3P_PONAB  ;  P27726, G3P_PSEAE  ;  P46406, G3P_RABIT  ;
DR   P52694, G3P_RALSO  ;  P04797, G3P_RAT    ;  Q8NK47, G3P_RHIMI  ;
DR   P32638, G3P_SCHCO  ;  P20287, G3P_SCHMA  ;  Q96US8, G3P_SCLSC  ;
DR   P24166, G3P_SERMA  ;  P24753, G3P_SEROD  ;  Q28554, G3P_SHEEP  ;
DR   Q8WZN0, G3P_SORMA  ;  Q4KYY3, G3P_SPECI  ;  P54226, G3P_STRAE  ;
DR   Q59800, G3P_STRAU  ;  Q9Z518, G3P_STRCO  ;  Q59906, G3P_STREQ  ;
DR   P0C0G7, G3P_STRP1  ;  P0DB18, G3P_STRP3  ;  Q5XDW3, G3P_STRP6  ;
DR   P68777, G3P_STRP8  ;  P0DB19, G3P_STRPQ  ;  P0C0G6, G3P_STRPY  ;
DR   P00361, G3P_THEAQ  ;  P17721, G3P_THEMA  ;  O83816, G3P_TREPA  ;
DR   P87197, G3P_TRIAT  ;  P09317, G3P_USTMA  ;  Q9UVC0, G3P_WICCI  ;
DR   P51009, G3P_XANFL  ;  P51469, G3P_XENLA  ;  Q6CCU7, G3P_YARLI  ;
DR   P08439, G3P_ZYGRO  ;  P09316, G3P_ZYMMO  ;
//
ID   1.2.1.13
DE   Glyceraldehyde-3-phosphate dehydrogenase (NADP(+)) (phosphorylating).
AN   NADP-dependent glyceraldehyde-3-phosphate dehydrogenase.
AN   Triosephosphate dehydrogenase (NADP(+)).
AN   Triosephosphate dehydrogenase (NADP+).
CA   D-glyceraldehyde 3-phosphate + phosphate + NADP(+) = 3-phospho-D-
CA   glyceroyl phosphate + NADPH.
PR   PROSITE; PDOC00069;
DR   P25856, G3PA_ARATH ;  P50362, G3PA_CHLRE ;  P34919, G3PA_CHOCR ;
DR   P30724, G3PA_GRAVE ;  P09315, G3PA_MAIZE ;  P12858, G3PA_PEA   ;
DR   Q8VXQ9, G3PA_SCEVA ;  P09672, G3PA_SINAL ;  P19866, G3PA_SPIOL ;
DR   P09043, G3PA_TOBAC ;  P25857, G3PB_ARATH ;  P12859, G3PB_PEA   ;
DR   P84544, G3PB_POPEU ;  P12860, G3PB_SPIOL ;  P09044, G3PB_TOBAC ;
//
ID   1.2.1.14
DE   Transferred entry: 1.1.1.205.
//
ID   1.2.1.15
DE   Malonate-semialdehyde dehydrogenase.
CA   3-oxopropanoate + NAD(P)(+) + H(2)O = malonate + NAD(P)H.
//
ID   1.2.1.16
DE   Succinate-semialdehyde dehydrogenase (NAD(P)(+)).
CA   Succinate semialdehyde + NAD(P)(+) + H(2)O = succinate + NAD(P)H.
PR   PROSITE; PDOC00068;
DR   Q7U2I0, GABD1_MYCBO;  P76149, SAD_ECOLI  ;  Q9US47, SSDH1_SCHPO;
DR   Q9UTM8, SSDH2_SCHPO;  P38067, UGA2_YEAST ;
//
ID   1.2.1.17
DE   Glyoxylate dehydrogenase (acylating).
CA   Glyoxylate + CoA + NADP(+) = oxalyl-CoA + NADPH.
//
ID   1.2.1.18
DE   Malonate-semialdehyde dehydrogenase (acetylating).
CA   3-oxopropanoate + CoA + NAD(P)(+) = acetyl-CoA + CO(2) + NAD(P)H.
DR   A0RDW1, IOLA1_BACAH;  Q81QR5, IOLA1_BACAN;  Q63BL0, IOLA1_BACCZ;
DR   Q6HJ19, IOLA1_BACHK;  Q65IX1, IOLA1_BACLD;  Q5WKZ1, IOLA1_BACSK;
DR   A9VF06, IOLA1_BACWK;  Q5L025, IOLA1_GEOKA;  A4IPB2, IOLA1_GEOTN;
DR   Q8ES27, IOLA1_OCEIH;  A0REB5, IOLA2_BACAH;  Q81QB6, IOLA2_BACAN;
DR   Q63B74, IOLA2_BACCZ;  Q6HIK3, IOLA2_BACHK;  Q65D00, IOLA2_BACLD;
DR   Q5WH11, IOLA2_BACSK;  A9VMS6, IOLA2_BACWK;  Q5KYR4, IOLA2_GEOKA;
DR   A4IPF5, IOLA2_GEOTN;  Q8EMV4, IOLA2_OCEIH;  Q4V1F6, IOLA3_BACCZ;
DR   Q5KYK0, IOLA3_GEOKA;  A7ZAI1, IOLA_BACA2 ;  Q738L2, IOLA_BACC1 ;
DR   B7IW48, IOLA_BACC2 ;  B7H597, IOLA_BACC4 ;  B7HR31, IOLA_BACC7 ;
DR   A7GPH3, IOLA_BACCN ;  B9IZZ7, IOLA_BACCQ ;  Q81DR5, IOLA_BACCR ;
DR   Q9KAH5, IOLA_BACHD ;  A7BJC4, IOLA_BACNA ;  A8FDV4, IOLA_BACP2 ;
DR   P42412, IOLA_BACSU ;  A5YBJ3, IOLA_LACCA ;  Q92EQ7, IOLA_LISIN ;
DR   C1KZ99, IOLA_LISMC ;  Q723T1, IOLA_LISMF ;  B8DCT8, IOLA_LISMH ;
DR   Q8Y9Y4, IOLA_LISMO ;  Q17M80, MMSA_AEDAE ;  Q7QC84, MMSA_ANOGA ;
DR   Q07536, MMSA_BOVIN ;  P52713, MMSA_CAEEL ;  Q54I10, MMSA_DICDI ;
DR   Q7KW39, MMSA_DROME ;  Q29HB2, MMSA_DROPS ;  Q02252, MMSA_HUMAN ;
DR   Q9EQ20, MMSA_MOUSE ;  Q02253, MMSA_RAT   ;
//
ID   1.2.1.19
DE   Aminobutyraldehyde dehydrogenase.
AN   1-pyrroline dehydrogenase.
AN   4-aminobutanal dehydrogenase.
AN   ABALDH.
AN   Gamma-guanidinobutyraldehyde dehydrogenase.
CA   4-aminobutanal + NAD(+) + H(2)O = 4-aminobutanoate + NADH.
CC   -!- The enzyme from some species exhibits broad substrate specificity and
CC       has a marked preference for straight-chain aldehydes (up to 7 carbon
CC       atoms) as substrates.
CC   -!- The plant enzyme also acts on 4-guanidinobutanal (cf. EC 1.2.1.54).
CC   -!- As 1-pyrroline and 4-aminobutanal are in equilibrium and can be
CC       interconverted spontaneously, 1-pyrroline may act as the starting
CC       substrate.
CC   -!- Formerly EC 1.5.1.35.
PR   PROSITE; PDOC00068;
DR   A8AGJ9, ABDH_CITK8 ;  A7ZLN7, ABDH_ECO24 ;  B7URJ0, ABDH_ECO27 ;
DR   B7MMS8, ABDH_ECO45 ;  B7L6F9, ABDH_ECO55 ;  Q8X9W5, ABDH_ECO57 ;
DR   B5Z0W0, ABDH_ECO5E ;  B7MUN0, ABDH_ECO81 ;  B7LZ33, ABDH_ECO8A ;
DR   C4ZVI3, ABDH_ECOBW ;  B1XDF5, ABDH_ECODH ;  A8A002, ABDH_ECOHS ;
DR   A1AB46, ABDH_ECOK1 ;  Q0THX6, ABDH_ECOL5 ;  Q8FHK7, ABDH_ECOL6 ;
DR   B1IS15, ABDH_ECOLC ;  P77674, ABDH_ECOLI ;  B7N4K1, ABDH_ECOLU ;
DR   B6IAI9, ABDH_ECOSE ;  B1LFH3, ABDH_ECOSM ;  Q1RBX3, ABDH_ECOUT ;
DR   A4WAR9, ABDH_ENT38 ;  Q6D6Y7, ABDH_ERWCT ;  B7LR95, ABDH_ESCF3 ;
DR   C6DD82, ABDH_PECCP ;  A9MQY3, ABDH_SALAR ;  Q57P61, ABDH_SALCH ;
DR   Q5PHV8, ABDH_SALPA ;  A9MYQ4, ABDH_SALPB ;  C0Q4N4, ABDH_SALPC ;
DR   Q8Z747, ABDH_SALTI ;  Q8ZPC9, ABDH_SALTY ;  A8GHZ8, ABDH_SERP5 ;
DR   Q32FQ5, ABDH_SHIDS ;  Q0T431, ABDH_SHIF8 ;  Q83R90, ABDH_SHIFL ;
DR   Q3Z1H6, ABDH_SHISS ;  P49189, AL9A1_HUMAN;
//
ID   1.2.1.20
DE   Glutarate-semialdehyde dehydrogenase.
CA   Glutarate semialdehyde + NAD(+) + H(2)O = glutarate + NADH.
//
ID   1.2.1.21
DE   Glycolaldehyde dehydrogenase.
CA   Glycolaldehyde + NAD(+) + H(2)O = glycolate + NADH.
DR   P25553, ALDA_ECOLI ;
//
ID   1.2.1.22
DE   Lactaldehyde dehydrogenase.
CA   (S)-lactaldehyde + NAD(+) + H(2)O = (S)-lactate + NADH.
PR   PROSITE; PDOC00068;
DR   P25553, ALDA_ECOLI ;  A6UVT6, LADH_META3 ;  Q58806, LADH_METJA ;
DR   A4FW36, LADH_METM5 ;  A6VH72, LADH_METM7 ;  Q6LX65, LADH_METMP ;
DR   A6UQD0, LADH_METVS ;
//
ID   1.2.1.23
DE   2-oxoaldehyde dehydrogenase (NAD(+)).
AN   Alpha-ketoaldehyde dehydrogenase.
AN   Methylglyoxal dehydrogenase.
CA   A 2-oxoaldehyde + NAD(+) + H(2)O = a 2-oxo acid + NADH.
CC   -!- Not identical with EC 1.2.1.49.
//
ID   1.2.1.24
DE   Succinate-semialdehyde dehydrogenase (NAD(+)).
CA   Succinate semialdehyde + NAD(+) + H(2)O = succinate + NADH.
CC   -!- This enzyme participates in the degradation of glutamate and
CC       4-aminobutyrate.
CC   -!- It is similar to EC 1.2.1.79 and EC 1.2.1.16 but is specific for
CC       NAD(+).
PR   PROSITE; PDOC00068;
DR   Q9SAK4, SSDH_ARATH ;  Q6A2H1, SSDH_GORGO ;  P51649, SSDH_HUMAN ;
DR   Q3MSM3, SSDH_HYLLA ;  Q8BWF0, SSDH_MOUSE ;  B9F3B6, SSDH_ORYSJ ;
DR   Q3MSM4, SSDH_PANPA ;  Q6A2H0, SSDH_PANTR ;  Q6A2H2, SSDH_PONPY ;
DR   P51650, SSDH_RAT   ;
//
ID   1.2.1.25
DE   2-oxoisovalerate dehydrogenase (acylating).
CA   3-methyl-2-oxobutanoate + CoA + NAD(+) = 2-methylpropanoyl-CoA + CO(2) +
CA   NADH.
CC   -!- Also acts on (S)-3-methyl-2-oxopentanoate and 4-methyl-2-
CC       oxopentanoate.
//
ID   1.2.1.26
DE   2,5-dioxovalerate dehydrogenase.
CA   2,5-dioxopentanoate + NADP(+) + H(2)O = 2-oxoglutarate + NADPH.
//
ID   1.2.1.27
DE   Methylmalonate-semialdehyde dehydrogenase (acylating).
AN   MMSA dehydrogenase.
AN   MSDH.
CA   2-methyl-3-oxopropanoate + CoA + H(2)O + NAD(+) = propanoyl-CoA +
CA   HCO(3)(-) + NADH.
CC   -!- Also converts 3-oxopropanoate into acetyl-CoA.
CC   -!- The reaction occurs in two steps with the decarboxylation process
CC       preceding CoA-binding.
CC   -!- Bicarbonate rather than CO(2) is released as a final product.
PR   PROSITE; PDOC00068;
DR   A0RDW1, IOLA1_BACAH;  Q81QR5, IOLA1_BACAN;  Q63BL0, IOLA1_BACCZ;
DR   Q6HJ19, IOLA1_BACHK;  Q65IX1, IOLA1_BACLD;  Q5WKZ1, IOLA1_BACSK;
DR   A9VF06, IOLA1_BACWK;  Q5L025, IOLA1_GEOKA;  A4IPB2, IOLA1_GEOTN;
DR   Q8ES27, IOLA1_OCEIH;  A0REB5, IOLA2_BACAH;  Q81QB6, IOLA2_BACAN;
DR   Q63B74, IOLA2_BACCZ;  Q6HIK3, IOLA2_BACHK;  Q65D00, IOLA2_BACLD;
DR   Q5WH11, IOLA2_BACSK;  A9VMS6, IOLA2_BACWK;  Q5KYR4, IOLA2_GEOKA;
DR   A4IPF5, IOLA2_GEOTN;  Q8EMV4, IOLA2_OCEIH;  Q4V1F6, IOLA3_BACCZ;
DR   Q5KYK0, IOLA3_GEOKA;  A7ZAI1, IOLA_BACA2 ;  Q738L2, IOLA_BACC1 ;
DR   B7IW48, IOLA_BACC2 ;  B7H597, IOLA_BACC4 ;  B7HR31, IOLA_BACC7 ;
DR   A7GPH3, IOLA_BACCN ;  B9IZZ7, IOLA_BACCQ ;  Q81DR5, IOLA_BACCR ;
DR   Q9KAH5, IOLA_BACHD ;  A7BJC4, IOLA_BACNA ;  A8FDV4, IOLA_BACP2 ;
DR   P42412, IOLA_BACSU ;  A5YBJ3, IOLA_LACCA ;  Q92EQ7, IOLA_LISIN ;
DR   C1KZ99, IOLA_LISMC ;  Q723T1, IOLA_LISMF ;  B8DCT8, IOLA_LISMH ;
DR   Q8Y9Y4, IOLA_LISMO ;  Q17M80, MMSA_AEDAE ;  Q7QC84, MMSA_ANOGA ;
DR   Q0WM29, MMSA_ARATH ;  Q07536, MMSA_BOVIN ;  P52713, MMSA_CAEEL ;
DR   Q54I10, MMSA_DICDI ;  Q7KW39, MMSA_DROME ;  Q29HB2, MMSA_DROPS ;
DR   Q02252, MMSA_HUMAN ;  Q9EQ20, MMSA_MOUSE ;  P28810, MMSA_PSEAE ;
DR   Q02253, MMSA_RAT   ;
//
ID   1.2.1.28
DE   Benzaldehyde dehydrogenase (NAD(+)).
CA   Benzaldehyde + NAD(+) + H(2)O = benzoate + NADH.
PR   PROSITE; PDOC00068;
DR   P46365, XYLC1_ACIGB;  P46366, XYLC2_ACIGB;  P43503, XYLC_PSEPU ;
//
ID   1.2.1.29
DE   Aryl-aldehyde dehydrogenase.
CA   An aromatic aldehyde + NAD(+) + H(2)O = an aromatic acid + NADH.
CC   -!- Oxidizes a number of aromatic aldehydes, but not aliphatic aldehydes.
//
ID   1.2.1.30
DE   Aryl-aldehyde dehydrogenase (NADP(+)).
CA   An aromatic aldehyde + NADP(+) + AMP + diphosphate + H(2)O = an aromatic
CA   acid + NADPH + ATP.
//
ID   1.2.1.31
DE   L-aminoadipate-semialdehyde dehydrogenase.
AN   2-aminoadipate semialdehyde dehydrogenase.
AN   2-aminoadipic semialdehyde dehydrogenase.
AN   Alpha-aminoadipate reductase.
AN   Alpha-aminoadipate-semialdehyde dehydrogenase.
AN   Aminoadipate semialdehyde dehydrogenase.
AN   L-alpha-aminoadipate delta-semialdehyde oxidoreductase.
AN   L-alpha-aminoadipate delta-semialdehyde:NAD oxidoreductase.
AN   L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine dinucleotide
AN   oxidoreductase.
CA   (S)-2-amino-6-oxohexanoate + NAD(P)(+) + H(2)O = L-2-aminoadipate +
CA   NAD(P)H.
PR   PROSITE; PDOC00427;
DR   Q80WC9, ACSF4_MOUSE;  P83402, AL7A1_ACASC;  Q2KJC9, AL7A1_BOVIN;
DR   P84463, AL7A1_CTEID;  P49419, AL7A1_HUMAN;  Q9DBF1, AL7A1_MOUSE;
DR   Q64057, AL7A1_RAT  ;  Q75BB3, LYS2_ASHGO ;  Q12572, LYS2_CANAL ;
DR   Q6FMI5, LYS2_CANGA ;  O74298, LYS2_PENCH ;  P40976, LYS2_SCHPO ;
DR   P07702, LYS2_YEAST ;
//
ID   1.2.1.32
DE   Aminomuconate-semialdehyde dehydrogenase.
CA   2-aminomuconate 6-semialdehyde + NAD(+) + H(2)O = 2-aminomuconate + NADH.
CC   -!- Also acts on 2-hydroxymuconate semialdehyde.
DR   Q9KWS5, AMNC_PSESP ;
//
ID   1.2.1.33
DE   (R)-dehydropantoate dehydrogenase.
AN   D-aldopantoate dehydrogenase.
CA   (R)-4-dehydropantoate + NAD(+) + H(2)O = (R)-3,3-dimethylmalate + NADH.
//
ID   1.2.1.34
DE   Transferred entry: 1.1.1.131.
//
ID   1.2.1.35
DE   Transferred entry: 1.1.1.203.
//
ID   1.2.1.36
DE   Retinal dehydrogenase.
CA   Retinal + NAD(+) + H(2)O = retinoate + NADH.
CF   FAD.
CC   -!- Acts on both the 11-trans- and 13-cis-forms of retinal.
DR   P48644, AL1A1_BOVIN;  P27463, AL1A1_CHICK;  P15437, AL1A1_HORSE;
DR   P00352, AL1A1_HUMAN;  Q8HYE4, AL1A1_MACFA;  P86886, AL1A1_MESAU;
DR   P24549, AL1A1_MOUSE;  Q8MI17, AL1A1_RABIT;  P51647, AL1A1_RAT  ;
DR   P51977, AL1A1_SHEEP;  O93344, AL1A2_CHICK;  O94788, AL1A2_HUMAN;
DR   Q62148, AL1A2_MOUSE;  Q63639, AL1A2_RAT  ;  Q9I8W8, AL1A2_TAEGU;
//
ID   1.2.1.37
DE   Transferred entry: 1.17.1.4.
//
ID   1.2.1.38
DE   N-acetyl-gamma-glutamyl-phosphate reductase.
AN   N-acetyl-glutamate semialdehyde dehydrogenase.
AN   NAGSA dehydrogenase.
CA   N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = N-acetyl-5-
CA   glutamyl phosphate + NADPH.
PR   PROSITE; PDOC00941;
DR   P78586, ARG56_CANAL;  Q54M18, ARG56_DICDI;  P54898, ARG56_NEUCR;
DR   P31318, ARG56_SCHPO;  Q01217, ARG56_YEAST;  Q9RVQ9, ARGC1_DEIRA;
DR   P59391, ARGC1_LACPL;  Q8YRB1, ARGC1_NOSS1;  Q88QQ6, ARGC1_PSEPK;
DR   Q9RY72, ARGC2_DEIRA;  O08318, ARGC2_LACPL;  P54894, ARGC2_NOSS1;
DR   P59308, ARGC2_PSEPK;  O50146, ARGC2_THET2;  B0CD68, ARGC_ACAM1 ;
DR   Q6FCI4, ARGC_ACIAD ;  B7H211, ARGC_ACIB3 ;  B7I933, ARGC_ACIB5 ;
DR   B2I2V4, ARGC_ACIBC ;  B0VQK3, ARGC_ACIBS ;  A3M5Z6, ARGC_ACIBT ;
DR   B0V684, ARGC_ACIBY ;  A0LUC5, ARGC_ACIC1 ;  B7JAI2, ARGC_ACIF2 ;
DR   B5EQH6, ARGC_ACIF5 ;  A0KFV0, ARGC_AERHH ;  Q9YBY8, ARGC_AERPE ;
DR   A4SIM2, ARGC_AERS4 ;  B9JD13, ARGC_AGRRK ;  Q8UG00, ARGC_AGRT5 ;
DR   B9JVB9, ARGC_AGRVS ;  B2UKZ6, ARGC_AKKM8 ;  Q0ABJ9, ARGC_ALHEH ;
DR   A6TTJ3, ARGC_ALKMQ ;  B4S0H8, ARGC_ALTMD ;  B9MR76, ARGC_ANATD ;
DR   Q3MG30, ARGC_ANAVT ;  O67724, ARGC_AQUAE ;  Q93Z70, ARGC_ARATH ;
DR   O28208, ARGC_ARCFU ;  Q5P7T9, ARGC_AROAE ;  A1R585, ARGC_ARTAT ;
DR   B8HGC3, ARGC_ARTCA ;  A0JV20, ARGC_ARTS2 ;  B6YQY8, ARGC_AZOPC ;
DR   C1DHY0, ARGC_AZOVD ;  A7Z3A7, ARGC_BACA2 ;  C3P7R8, ARGC_BACAA ;
DR   C3LJQ9, ARGC_BACAC ;  Q846B4, ARGC_BACAM ;  Q81M95, ARGC_BACAN ;
DR   Q731G3, ARGC_BACC1 ;  C1ER06, ARGC_BACC3 ;  B7HB04, ARGC_BACC4 ;
DR   B7HNP9, ARGC_BACC7 ;  A7GSF4, ARGC_BACCN ;  B9IXC9, ARGC_BACCQ ;
DR   Q5LHZ1, ARGC_BACFN ;  Q64YZ5, ARGC_BACFR ;  Q9K8V2, ARGC_BACHD ;
DR   Q6HE28, ARGC_BACHK ;  Q65LF0, ARGC_BACLD ;  Q5WEW7, ARGC_BACSK ;
DR   P23715, ARGC_BACSU ;  Q8A1A7, ARGC_BACTN ;  A6KXY5, ARGC_BACV8 ;
DR   A9VG72, ARGC_BACWK ;  B8DU54, ARGC_BIFA0 ;  B3DSZ3, ARGC_BIFLD ;
DR   P59305, ARGC_BIFLO ;  Q2KV05, ARGC_BORA1 ;  Q7WFC5, ARGC_BORBR ;
DR   Q7W3Z3, ARGC_BORPA ;  A9I242, ARGC_BORPD ;  Q7VUW0, ARGC_BORPE ;
DR   C0QYU7, ARGC_BRAHW ;  A5EB56, ARGC_BRASB ;  A4Z1S1, ARGC_BRASO ;
DR   C0Z6T1, ARGC_BREBN ;  B2S533, ARGC_BRUA1 ;  Q2YNE1, ARGC_BRUA2 ;
DR   Q57DW4, ARGC_BRUAB ;  A9MAG5, ARGC_BRUC2 ;  C0RIC3, ARGC_BRUMB ;
DR   Q8YGI8, ARGC_BRUME ;  A5VPX1, ARGC_BRUO2 ;  B0CLB5, ARGC_BRUSI ;
DR   P59314, ARGC_BRUSU ;  B8D8K6, ARGC_BUCA5 ;  P57156, ARGC_BUCAI ;
DR   Q8KA61, ARGC_BUCAP ;  B8D6W0, ARGC_BUCAT ;  Q1BK31, ARGC_BURCA ;
DR   B1K264, ARGC_BURCC ;  A0B466, ARGC_BURCH ;  B4EG04, ARGC_BURCJ ;
DR   Q0B5P6, ARGC_BURCM ;  Q38ZT5, ARGC_BURS3 ;  A8M8Q9, ARGC_CALMQ ;
DR   A4XJN9, ARGC_CALS8 ;  A7H097, ARGC_CAMC5 ;  A7I2W9, ARGC_CAMHC ;
DR   A8FK14, ARGC_CAMJ8 ;  A7H1S3, ARGC_CAMJD ;  Q9PIS0, ARGC_CAMJE ;
DR   A1VXU6, ARGC_CAMJJ ;  Q5HWN8, ARGC_CAMJR ;  B8H555, ARGC_CAUCN ;
DR   Q9A8H5, ARGC_CAUCR ;  B3PL73, ARGC_CELJU ;  A0RWW0, ARGC_CENSY ;
DR   Q8KDE3, ARGC_CHLTE ;  Q7NRT5, ARGC_CHRVO ;  A5CSI9, ARGC_CLAM3 ;
DR   B0RHD0, ARGC_CLAMS ;  Q97GH7, ARGC_CLOAB ;  A6M1Z6, ARGC_CLOB8 ;
DR   B2UYI2, ARGC_CLOBA ;  B2TQ25, ARGC_CLOBB ;  B9E1X0, ARGC_CLOK1 ;
DR   A5N8G4, ARGC_CLOK5 ;  A0Q1F0, ARGC_CLONN ;  A9KHN1, ARGC_CLOPH ;
DR   A3DGK5, ARGC_CLOTH ;  C3PGJ1, ARGC_CORA7 ;  Q6NHH0, ARGC_CORDI ;
DR   Q8FTN5, ARGC_COREF ;  A4QDY8, ARGC_CORGB ;  Q59279, ARGC_CORGL ;
DR   C4LID5, ARGC_CORK4 ;  B1WYI6, ARGC_CYAA5 ;  B8HY92, ARGC_CYAP4 ;
DR   B7KF19, ARGC_CYAP7 ;  B7JY20, ARGC_CYAP8 ;  Q3Z629, ARGC_DEHE1 ;
DR   A5FPC2, ARGC_DEHSB ;  Q3ZZX5, ARGC_DEHSC ;  C1D141, ARGC_DEIDV ;
DR   Q1IXY5, ARGC_DEIGD ;  C0QI21, ARGC_DESAH ;  B1I1C5, ARGC_DESAP ;
DR   Q6ANM0, ARGC_DESPS ;  A4J167, ARGC_DESRM ;  B5YAL8, ARGC_DICT6 ;
DR   B8E0N8, ARGC_DICTD ;  Q8X732, ARGC_ECO57 ;  P59306, ARGC_ECOL6 ;
DR   P11446, ARGC_ECOLI ;  Q3YR04, ARGC_EHRCJ ;  Q2GFI0, ARGC_EHRCR ;
DR   Q5FGD5, ARGC_EHRRG ;  Q5HA98, ARGC_EHRRW ;  Q6DAR1, ARGC_ERWCT ;
DR   C4Z4C2, ARGC_EUBE2 ;  B1YJL9, ARGC_EXIS2 ;  A5FEC6, ARGC_FLAJ1 ;
DR   Q2J860, ARGC_FRASC ;  B5EFN1, ARGC_GEOBB ;  Q5L1V5, ARGC_GEOKA ;
DR   Q39Y23, ARGC_GEOMG ;  Q07906, ARGC_GEOSE ;  B9M6W2, ARGC_GEOSF ;
DR   Q748X6, ARGC_GEOSL ;  C6E4S6, ARGC_GEOSM ;  C5D764, ARGC_GEOSW ;
DR   A4IL46, ARGC_GEOTN ;  A5GAY8, ARGC_GEOUR ;  Q7NE70, ARGC_GLOVI ;
DR   A0M376, ARGC_GRAFK ;  A1WVE4, ARGC_HALHL ;  Q5UZ50, ARGC_HALMA ;
DR   B8D1G6, ARGC_HALOH ;  Q18E32, ARGC_HALWD ;  B0TCA6, ARGC_HELMI ;
DR   A4G1T4, ARGC_HERAR ;  Q5QX02, ARGC_IDILO ;  A8AAF8, ARGC_IGNH4 ;
DR   A6SUN9, ARGC_JANMA ;  Q28PV9, ARGC_JANSC ;  C5CHW7, ARGC_KOSOT ;
DR   B2GBN0, ARGC_LACF3 ;  Q9CHD5, ARGC_LACLA ;  C1D5B2, ARGC_LARHH ;
DR   Q6AGD3, ARGC_LEIXX ;  Q04T45, ARGC_LEPBJ ;  Q051G7, ARGC_LEPBL ;
DR   Q72RJ9, ARGC_LEPIC ;  P59307, ARGC_LEPIN ;  Q92BB7, ARGC_LISIN ;
DR   C1KVN8, ARGC_LISMC ;  Q71Z76, ARGC_LISMF ;  B8DHF0, ARGC_LISMH ;
DR   Q8Y6U1, ARGC_LISMO ;  A0AJ40, ARGC_LISW6 ;  A0L482, ARGC_MAGSM ;
DR   A1TYH0, ARGC_MARAV ;  Q11J68, ARGC_MESSB ;  A6UWL8, ARGC_META3 ;
DR   Q8TK53, ARGC_METAC ;  A7I4D1, ARGC_METB6 ;  Q46B07, ARGC_METBF ;
DR   B3E0U0, ARGC_METI4 ;  Q58496, ARGC_METJA ;  Q8TWF8, ARGC_METKA ;
DR   A2STZ4, ARGC_METLZ ;  A4G075, ARGC_METM5 ;  A9A8I0, ARGC_METM6 ;
DR   A6VIA5, ARGC_METM7 ;  Q8PZL6, ARGC_METMA ;  A3CRT6, ARGC_METMJ ;
DR   Q6M102, ARGC_METMP ;  B8GFN1, ARGC_METPE ;  A5ULI7, ARGC_METS3 ;
DR   B0UPC4, ARGC_METS4 ;  Q2NGV2, ARGC_METST ;  O26934, ARGC_METTH ;
DR   A0B6F6, ARGC_METTP ;  A6UR99, ARGC_METVS ;  B0JXE8, ARGC_MICAN ;
DR   C5CAN3, ARGC_MICLC ;  Q2RG62, ARGC_MOOTA ;  Q9K4Z1, ARGC_MORAB ;
DR   Q9K4Z6, ARGC_MORPR ;  A0QHB4, ARGC_MYCA1 ;  B1MAZ6, ARGC_MYCA9 ;
DR   P63563, ARGC_MYCBO ;  A1KJ69, ARGC_MYCBP ;  C1ANS5, ARGC_MYCBT ;
DR   B8ZRK2, ARGC_MYCLB ;  Q9CC15, ARGC_MYCLE ;  Q740I9, ARGC_MYCPA ;
DR   A5U309, ARGC_MYCTA ;  P63562, ARGC_MYCTU ;  Q3IMD8, ARGC_NATPD ;
DR   Q5FAA9, ARGC_NEIG1 ;  B4RQ50, ARGC_NEIG2 ;  A9M1W9, ARGC_NEIM0 ;
DR   Q9JVU6, ARGC_NEIMA ;  Q9JY18, ARGC_NEIMB ;  A1KSA9, ARGC_NEIMF ;
DR   Q0AHZ8, ARGC_NITEC ;  Q82UK2, ARGC_NITEU ;  A9A1K6, ARGC_NITMS ;
DR   Q2YBK4, ARGC_NITMU ;  Q3JC91, ARGC_NITOC ;  O87890, ARGC_NOSEL ;
DR   Q8CUN2, ARGC_OCEIH ;  A6X1V9, ARGC_OCHA4 ;  B6JHG4, ARGC_OLICO ;
DR   Q6AV34, ARGC_ORYSJ ;  A6L849, ARGC_PARD8 ;  A1B2K9, ARGC_PARDP ;
DR   P57907, ARGC_PASMU ;  C6DI81, ARGC_PECCP ;  Q3A3B8, ARGC_PELCD ;
DR   B4S9V0, ARGC_PELPB ;  A1ATK5, ARGC_PELPD ;  A5D504, ARGC_PELTS ;
DR   Q7MYD6, ARGC_PHOLL ;  Q6KYZ5, ARGC_PICTO ;  A4T032, ARGC_POLSQ ;
DR   A3PCW5, ARGC_PROM0 ;  A2C239, ARGC_PROM1 ;  A8G4T4, ARGC_PROM2 ;
DR   A9BAE1, ARGC_PROM4 ;  A2BWM0, ARGC_PROM5 ;  Q31AX7, ARGC_PROM9 ;
DR   Q7VBZ8, ARGC_PROMA ;  Q7V7N1, ARGC_PROMM ;  Q7V1H9, ARGC_PROMP ;
DR   A2BR42, ARGC_PROMS ;  Q46L18, ARGC_PROMT ;  Q48NN7, ARGC_PSE14 ;
DR   Q15X80, ARGC_PSEA6 ;  A6UZG3, ARGC_PSEA7 ;  B7V620, ARGC_PSEA8 ;
DR   Q02TA4, ARGC_PSEAB ;  Q9I5Q9, ARGC_PSEAE ;  Q1IFY8, ARGC_PSEE4 ;
DR   C3K2Z7, ARGC_PSEFS ;  A4XZB4, ARGC_PSEMY ;  A5VXM5, ARGC_PSEP1 ;
DR   Q3K5W5, ARGC_PSEPF ;  B0KK45, ARGC_PSEPG ;  B1JE24, ARGC_PSEPW ;
DR   Q889Z3, ARGC_PSESM ;  Q4ZMM3, ARGC_PSEU2 ;  Q4FRK9, ARGC_PSYA2 ;
DR   Q1QA46, ARGC_PSYCK ;  A5WFU8, ARGC_PSYWF ;  Q9V1I6, ARGC_PYRAB ;
DR   Q8ZUA0, ARGC_PYRAE ;  A3MT41, ARGC_PYRCJ ;  Q8U0B6, ARGC_PYRFU ;
DR   O59397, ARGC_PYRHO ;  A1RR73, ARGC_PYRIL ;  Q5JFW1, ARGC_PYRKO ;
DR   Q8Y339, ARGC_RALSO ;  A9WQ84, ARGC_RENSM ;  B3PVH2, ARGC_RHIE6 ;
DR   Q2K9W7, ARGC_RHIEC ;  Q9AKR8, ARGC_RHIET ;  Q1MIP7, ARGC_RHIL3 ;
DR   Q982X3, ARGC_RHILO ;  B5ZXZ1, ARGC_RHILW ;  Q92QR7, ARGC_RHIME ;
DR   C3MA29, ARGC_RHISN ;  Q7UVL4, ARGC_RHOBA ;  Q9LA02, ARGC_RHOCB ;
DR   Q2RRM4, ARGC_RHORT ;  A3PK36, ARGC_RHOS1 ;  Q3J277, ARGC_RHOS4 ;
DR   A4WQY7, ARGC_RHOS5 ;  B9KSY0, ARGC_RHOSK ;  Q163W4, ARGC_ROSDO ;
DR   Q1AS32, ARGC_RUBXD ;  A1AXV8, ARGC_RUTMC ;  Q21MI4, ARGC_SACD2 ;
DR   A4FKC8, ARGC_SACEN ;  A8LY49, ARGC_SALAI ;  Q5PK75, ARGC_SALPA ;
DR   Q8Z309, ARGC_SALTI ;  A4X650, ARGC_SALTO ;  Q8ZKL8, ARGC_SALTY ;
DR   B8EBG3, ARGC_SHEB2 ;  A3DA26, ARGC_SHEB5 ;  A6WTS3, ARGC_SHEB8 ;
DR   A9KTZ0, ARGC_SHEB9 ;  Q12SN0, ARGC_SHEDO ;  Q089L1, ARGC_SHEFN ;
DR   B0TL88, ARGC_SHEHH ;  A3Q9C6, ARGC_SHELP ;  P59309, ARGC_SHEON ;
DR   A8GZ18, ARGC_SHEPA ;  B8CNH7, ARGC_SHEPW ;  A0L254, ARGC_SHESA ;
DR   A8G1A7, ARGC_SHESH ;  Q0HDU5, ARGC_SHESM ;  Q0I064, ARGC_SHESR ;
DR   B1KND3, ARGC_SHEWM ;  P59310, ARGC_SHIFL ;  Q5LS92, ARGC_SILPO ;
DR   Q1GHL0, ARGC_SILST ;  A6U7T4, ARGC_SINMW ;  A7WXH5, ARGC_STAA1 ;
DR   Q2FK78, ARGC_STAA3 ;  Q2G1H4, ARGC_STAA8 ;  Q5HJI9, ARGC_STAAC ;
DR   P63564, ARGC_STAAM ;  P63565, ARGC_STAAN ;  Q6GKC2, ARGC_STAAR ;
DR   Q6GCU2, ARGC_STAAS ;  Q8NYM6, ARGC_STAAW ;  Q5HP21, ARGC_STAEQ ;
DR   Q8CP35, ARGC_STAES ;  Q4A0N1, ARGC_STAS1 ;  Q828A6, ARGC_STRAW ;
DR   P54896, ARGC_STRCL ;  P54895, ARGC_STRCO ;  A8AYI7, ARGC_STRGC ;
DR   B4SQ93, ARGC_STRM5 ;  B2FMD7, ARGC_STRMK ;  P59311, ARGC_STRMU ;
DR   A3CLY4, ARGC_STRSV ;  Q5M123, ARGC_STRT1 ;  Q5M5L1, ARGC_STRT2 ;
DR   Q03LZ4, ARGC_STRTD ;  Q4JAQ3, ARGC_SULAC ;  Q30QC1, ARGC_SULDN ;
DR   A8Z5X3, ARGC_SULMW ;  A6Q9U8, ARGC_SULNB ;  Q980X1, ARGC_SULSO ;
DR   Q976J5, ARGC_SULTO ;  Q67KC3, ARGC_SYMTH ;  Q31NA6, ARGC_SYNE7 ;
DR   A0LIV2, ARGC_SYNFM ;  B1XIA1, ARGC_SYNP2 ;  Q5N5V5, ARGC_SYNP6 ;
DR   Q7U6S4, ARGC_SYNPX ;  Q3AJT9, ARGC_SYNSC ;  P54899, ARGC_SYNY3 ;
DR   C5BP49, ARGC_TERTT ;  P59312, ARGC_THEEB ;  Q47N79, ARGC_THEFY ;
DR   A8F448, ARGC_THELT ;  Q9X2A2, ARGC_THEMA ;  Q9Z4S2, ARGC_THENN ;
DR   B1YB54, ARGC_THENV ;  A5ILL3, ARGC_THEP1 ;  B0KBV9, ARGC_THEP3 ;
DR   B0K4D2, ARGC_THEPX ;  B9KZP8, ARGC_THERP ;  B1LAP2, ARGC_THESQ ;
DR   P96136, ARGC_THET2 ;  Q8R7B8, ARGC_THETN ;  Q3SF19, ARGC_THIDA ;
DR   B8GLD4, ARGC_THISH ;  C4L7S5, ARGC_TOLAT ;  Q110V5, ARGC_TRIEI ;
DR   Q0W932, ARGC_UNCMA ;  B1GYR2, ARGC_UNCTG ;  A5CVH0, ARGC_VESOH ;
DR   Q9KNT6, ARGC_VIBCH ;  Q5E2E5, ARGC_VIBF1 ;  Q87L55, ARGC_VIBPA ;
DR   P59313, ARGC_VIBVU ;  Q7MH70, ARGC_VIBVY ;  Q7M7U1, ARGC_WOLSU ;
DR   Q8PK31, ARGC_XANAC ;  Q3BSI7, ARGC_XANC5 ;  Q4UVI5, ARGC_XANC8 ;
DR   B0RS54, ARGC_XANCB ;  Q8P8J8, ARGC_XANCP ;  Q2P2F6, ARGC_XANOM ;
DR   B2I7K9, ARGC_XYLF2 ;  Q9PEM6, ARGC_XYLFA ;  Q87EL1, ARGC_XYLFT ;
DR   Q8ZA86, ARGC_YERPE ;  Q66G72, ARGC_YERPS ;
//
ID   1.2.1.39
DE   Phenylacetaldehyde dehydrogenase.
CA   Phenylacetaldehyde + NAD(+) + H(2)O = phenylacetate + NADH.
PR   PROSITE; PDOC00068;
DR   P80668, FEAB_ECOLI ;
//
ID   1.2.1.40
DE   3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase.
AN   3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-dehydrogenase.
CA   (25R)-3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al + NAD(+)
CA   + H(2)O = (25R)-3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-
CA   oate + NADH.
//
ID   1.2.1.41
DE   Glutamate-5-semialdehyde dehydrogenase.
AN   Beta-glutamylphosphate reductase.
AN   Gamma-glutamylphosphate reductase.
AN   Glutamyl-gamma-semialdehyde dehydrogenase.
CA   L-glutamate 5-semialdehyde + phosphate + NADP(+) = L-glutamyl 5-phosphate
CA   + NADPH.
PR   PROSITE; PDOC00940;
DR   P54889, ALH13_CAEEL;  P54887, P5CS1_ARATH;  P54888, P5CS2_ARATH;
DR   O04015, P5CS_ACTDE ;  P54886, P5CS_HUMAN ;  O65361, P5CS_MESCR ;
DR   Q9Z110, P5CS_MOUSE ;  O04226, P5CS_ORYSJ ;  Q5R4M8, P5CS_PONAB ;
DR   Q96480, P5CS_SOLLC ;  P32296, P5CS_VIGAC ;  Q65KU7, PROA1_BACLD;
DR   Q65IS9, PROA2_BACLD;  B0CFL0, PROA_ACAM1 ;  A1TVU4, PROA_ACIAC ;
DR   Q6FEN5, PROA_ACIAD ;  B7H081, PROA_ACIB3 ;  B7I5F5, PROA_ACIB5 ;
DR   B2I3D3, PROA_ACIBC ;  Q1IS80, PROA_ACIBL ;  B0VKT1, PROA_ACIBS ;
DR   A3M1Z8, PROA_ACIBT ;  B0V4S6, PROA_ACIBY ;  A5FYS4, PROA_ACICJ ;
DR   B9MH63, PROA_ACIET ;  A1WCP4, PROA_ACISJ ;  A3N3P3, PROA_ACTP2 ;
DR   B3H321, PROA_ACTP7 ;  B0BTX9, PROA_ACTPJ ;  A6VMV2, PROA_ACTSZ ;
DR   A0KNQ8, PROA_AERHH ;  A4SJF6, PROA_AERS4 ;  B9JER3, PROA_AGRRK ;
DR   Q8UBS1, PROA_AGRT5 ;  B9JUH7, PROA_AGRVS ;  Q0VN49, PROA_ALCBS ;
DR   Q0ABN0, PROA_ALHEH ;  A6TUA0, PROA_ALKMQ ;  A8MFQ5, PROA_ALKOO ;
DR   B8J8Z7, PROA_ANAD2 ;  Q2IMG0, PROA_ANADE ;  A7H6U9, PROA_ANADF ;
DR   B4UM59, PROA_ANASK ;  B9MK80, PROA_ANATD ;  Q3MH53, PROA_ANAVT ;
DR   B7GJH1, PROA_ANOFW ;  O67166, PROA_AQUAE ;  A8EVN0, PROA_ARCB4 ;
DR   Q5P255, PROA_AROAE ;  B6YS10, PROA_AZOPC ;  A1KAH8, PROA_AZOSB ;
DR   C1DMQ0, PROA_AZOVD ;  A7Z3T1, PROA_BACA2 ;  C3NZU4, PROA_BACAA ;
DR   C3LEW9, PROA_BACAC ;  Q81P27, PROA_BACAN ;  B7JD15, PROA_BACC0 ;
DR   Q735X3, PROA_BACC1 ;  B7ILK1, PROA_BACC2 ;  C1EZ15, PROA_BACC3 ;
DR   B7H673, PROA_BACC4 ;  B7HVK6, PROA_BACC7 ;  B9J498, PROA_BACCQ ;
DR   Q639W9, PROA_BACCZ ;  Q5LI24, PROA_BACFN ;  Q64Z29, PROA_BACFR ;
DR   Q9KCR5, PROA_BACHD ;  Q6HHC2, PROA_BACHK ;  Q5WH54, PROA_BACSK ;
DR   P39821, PROA_BACSU ;  Q8A1E8, PROA_BACTN ;  A6KXU8, PROA_BACV8 ;
DR   A9VK31, PROA_BACWK ;  A1URN6, PROA_BARBK ;  Q6G4Z0, PROA_BARHE ;
DR   Q6G0S6, PROA_BARQU ;  A9IMB2, PROA_BART1 ;  B2IE42, PROA_BEII9 ;
DR   A1A1U9, PROA_BIFAA ;  Q8G5H9, PROA_BIFLO ;  B7GTL2, PROA_BIFLS ;
DR   Q2KXE0, PROA_BORA1 ;  Q7WH30, PROA_BORBR ;  Q7W9M7, PROA_BORPA ;
DR   A9HWX2, PROA_BORPD ;  Q7VWZ0, PROA_BORPE ;  C0R0B8, PROA_BRAHW ;
DR   Q89X85, PROA_BRAJA ;  A5E961, PROA_BRASB ;  A4YKF1, PROA_BRASO ;
DR   Q2YLI7, PROA_BRUA2 ;  Q57B47, PROA_BRUAB ;  A9M880, PROA_BRUC2 ;
DR   C0RF92, PROA_BRUMB ;  Q8YJ78, PROA_BRUME ;  A5VSI3, PROA_BRUO2 ;
DR   A9WWW7, PROA_BRUSI ;  Q8FYM3, PROA_BRUSU ;  B1YTB0, PROA_BURA4 ;
DR   Q1BZ67, PROA_BURCA ;  B1JVH2, PROA_BURCC ;  A0K4I3, PROA_BURCH ;
DR   Q0BIB2, PROA_BURCM ;  Q62H23, PROA_BURMA ;  Q3JNN5, PROA_BURP1 ;
DR   B2JGX3, PROA_BURP8 ;  B2SYN3, PROA_BURPP ;  Q63QT9, PROA_BURPS ;
DR   Q39JM2, PROA_BURS3 ;  Q2SZ88, PROA_BURTA ;  A4JBI4, PROA_BURVG ;
DR   Q13U85, PROA_BURXL ;  A4XK60, PROA_CALS8 ;  A7GVZ7, PROA_CAMC5 ;
DR   P53000, PROA_CAMJE ;  A1VYR7, PROA_CAMJJ ;  Q3AF39, PROA_CARHZ ;
DR   Q9A2X6, PROA_CAUCR ;  B0T315, PROA_CAUSK ;  A9WBM7, PROA_CHLAA ;
DR   B8G8E0, PROA_CHLAD ;  Q3ARL1, PROA_CHLCH ;  B3EE24, PROA_CHLL2 ;
DR   B3QPW0, PROA_CHLP8 ;  B3EPD4, PROA_CHLPB ;  B9LE47, PROA_CHLSY ;
DR   Q8KCE9, PROA_CHLTE ;  Q1QXB4, PROA_CHRSD ;  Q7NQ51, PROA_CHRVO ;
DR   A8AKP4, PROA_CITK8 ;  A5CR34, PROA_CLAM3 ;  Q97E62, PROA_CLOAB ;
DR   A6LPD5, PROA_CLOB8 ;  B2UX78, PROA_CLOBA ;  B2THG5, PROA_CLOBB ;
DR   B8I6T0, PROA_CLOCE ;  B9E4Q5, PROA_CLOK1 ;  A5N0V1, PROA_CLOK5 ;
DR   A0PXA4, PROA_CLONN ;  Q0TM73, PROA_CLOP1 ;  Q8XHA7, PROA_CLOPE ;
DR   A9KMV0, PROA_CLOPH ;  Q0SPX8, PROA_CLOPS ;  Q896G4, PROA_CLOTE ;
DR   A3DC22, PROA_CLOTH ;  Q47UQ0, PROA_COLP3 ;  Q6NFW0, PROA_CORDI ;
DR   Q8FN87, PROA_COREF ;  A4QG75, PROA_CORGB ;  P0C1E0, PROA_CORGL ;
DR   Q4JWT3, PROA_CORJK ;  P0C1E1, PROA_CORML ;  Q0K710, PROA_CUPNH ;
DR   Q46XE1, PROA_CUPPJ ;  B3R6R0, PROA_CUPTR ;  B8HYG3, PROA_CYAP4 ;
DR   Q47IN4, PROA_DECAR ;  Q3Z6Z9, PROA_DEHE1 ;  A5FQ48, PROA_DEHSB ;
DR   Q3ZYH9, PROA_DEHSC ;  Q1IZP1, PROA_DEIGD ;  Q9RTD9, PROA_DEIRA ;
DR   A9C1G5, PROA_DELAS ;  B8FM70, PROA_DESAA ;  C6BSC1, PROA_DESAD ;
DR   C0QLF1, PROA_DESAH ;  B8J495, PROA_DESDA ;  Q311G6, PROA_DESDG ;
DR   B8FUB6, PROA_DESHD ;  Q24XR6, PROA_DESHY ;  C4XSQ4, PROA_DESMR ;
DR   A8ZRY3, PROA_DESOH ;  Q6AK09, PROA_DESPS ;  A4J3Q0, PROA_DESRM ;
DR   Q72AN9, PROA_DESVH ;  A1VCR9, PROA_DESVV ;  B5YEQ8, PROA_DICT6 ;
DR   B8E0D2, PROA_DICTD ;  A8LK12, PROA_DINSH ;  A7ZI02, PROA_ECO24 ;
DR   B7UJD1, PROA_ECO27 ;  B7MC93, PROA_ECO45 ;  B7L3Z5, PROA_ECO55 ;
DR   Q8X7N4, PROA_ECO57 ;  B5Z1I7, PROA_ECO5E ;  B7NK82, PROA_ECO7I ;
DR   B7MQ79, PROA_ECO81 ;  B7M272, PROA_ECO8A ;  C4ZTA0, PROA_ECOBW ;
DR   B1XDY6, PROA_ECODH ;  A7ZWK6, PROA_ECOHS ;  A1A7V4, PROA_ECOK1 ;
DR   Q0TL73, PROA_ECOL5 ;  Q8FKM3, PROA_ECOL6 ;  B1J0Z1, PROA_ECOLC ;
DR   P07004, PROA_ECOLI ;  B7N8H4, PROA_ECOLU ;  B6I023, PROA_ECOSE ;
DR   B1LHT9, PROA_ECOSM ;  Q1RFS7, PROA_ECOUT ;  A4W6X5, PROA_ENT38 ;
DR   Q839W3, PROA_ENTFA ;  A7MI49, PROA_ENTS8 ;  Q6D1I4, PROA_ERWCT ;
DR   B2VHM6, PROA_ERWT9 ;  Q2N9V1, PROA_ERYLH ;  B7LNF7, PROA_ESCF3 ;
DR   C4Z075, PROA_EUBE2 ;  C4Z9V4, PROA_EUBR3 ;  B0U111, PROA_FRAP2 ;
DR   Q2JDN7, PROA_FRASC ;  A8L1V4, PROA_FRASN ;  B5EEI4, PROA_GEOBB ;
DR   Q5KYA2, PROA_GEOKA ;  B3E3M7, PROA_GEOLS ;  Q39QR2, PROA_GEOMG ;
DR   B9M0D6, PROA_GEOSF ;  Q747Q4, PROA_GEOSL ;  C6E7L9, PROA_GEOSM ;
DR   C5D2V2, PROA_GEOSW ;  A4IPN4, PROA_GEOTN ;  A5G906, PROA_GEOUR ;
DR   Q7NEF6, PROA_GLOVI ;  Q5FRT2, PROA_GLUOX ;  Q4QJW6, PROA_HAEI8 ;
DR   A5UBQ2, PROA_HAEIE ;  A5UF66, PROA_HAEIG ;  P45121, PROA_HAEIN ;
DR   B8F6K8, PROA_HAEPS ;  Q0I2E5, PROA_HAES1 ;  B0USH2, PROA_HAES2 ;
DR   Q2SA27, PROA_HAHCH ;  A1WYZ4, PROA_HALHL ;  B8D0Y6, PROA_HALOH ;
DR   Q18J39, PROA_HALWD ;  Q7VI05, PROA_HELHP ;  B0TBV8, PROA_HELMI ;
DR   A4G8E9, PROA_HERAR ;  B4U8A0, PROA_HYDS0 ;  Q0BWP1, PROA_HYPNA ;
DR   Q5QY68, PROA_IDILO ;  A6T242, PROA_JANMA ;  Q28Q10, PROA_JANSC ;
DR   A6WDM6, PROA_KINRD ;  B5Y169, PROA_KLEP3 ;  A6T561, PROA_KLEP7 ;
DR   C5CE09, PROA_KOSOT ;  Q035M3, PROA_LACC3 ;  B3WA82, PROA_LACCB ;
DR   Q9CF73, PROA_LACLA ;  A2RJM8, PROA_LACLM ;  Q02XW0, PROA_LACLS ;
DR   Q890J4, PROA_LACPL ;  A5VIE0, PROA_LACRD ;  B2G5W8, PROA_LACRJ ;
DR   Q1WRR6, PROA_LACS1 ;  C1D6E4, PROA_LARHH ;  Q5X4U9, PROA_LEGPA ;
DR   A5ICA4, PROA_LEGPC ;  Q5ZV33, PROA_LEGPH ;  Q5WWN7, PROA_LEGPL ;
DR   Q6AFX9, PROA_LEIXX ;  B0S9A5, PROA_LEPBA ;  Q04Q92, PROA_LEPBJ ;
DR   Q054P8, PROA_LEPBL ;  B0SRT9, PROA_LEPBP ;  Q72NQ9, PROA_LEPIC ;
DR   P94872, PROA_LEPIN ;  B1MX68, PROA_LEUCK ;  Q03ZF1, PROA_LEUMM ;
DR   Q92CE5, PROA_LISIN ;  C1L2G7, PROA_LISMC ;  Q720G3, PROA_LISMF ;
DR   B8DHP3, PROA_LISMH ;  Q93Q55, PROA_LISMO ;  A0AI64, PROA_LISW6 ;
DR   Q2VZT9, PROA_MAGSA ;  A0LCZ1, PROA_MAGSM ;  Q65S49, PROA_MANSM ;
DR   A1U3C3, PROA_MARAV ;  Q0AL88, PROA_MARMM ;  A6VZ85, PROA_MARMS ;
DR   O86053, PROA_MEIRU ;  Q11CP8, PROA_MESSB ;  Q9HHA1, PROA_METAC ;
DR   Q46F78, PROA_METBF ;  Q12TF9, PROA_METBU ;  B7KS47, PROA_METC4 ;
DR   Q606Y1, PROA_METCA ;  A9W6Q2, PROA_METEP ;  Q1GZB2, PROA_METFK ;
DR   Q8PYP2, PROA_METMA ;  B8IEM1, PROA_METNO ;  B1ZFJ0, PROA_METPB ;
DR   A2SCE2, PROA_METPP ;  B1M695, PROA_METRJ ;  B0UMS9, PROA_METS4 ;
DR   B8EQH0, PROA_METSB ;  B0JWW5, PROA_MICAN ;  Q2RKZ6, PROA_MOOTA ;
DR   P65789, PROA_MYCBO ;  A1KLC0, PROA_MYCBP ;  C1AQZ3, PROA_MYCBT ;
DR   A4T2I0, PROA_MYCGI ;  B8ZRN0, PROA_MYCLB ;  Q9CBZ7, PROA_MYCLE ;
DR   B2HME9, PROA_MYCMM ;  Q73XR2, PROA_MYCPA ;  A0R115, PROA_MYCS2 ;
DR   A3Q2E3, PROA_MYCSJ ;  A1UIZ7, PROA_MYCSK ;  Q1B639, PROA_MYCSS ;
DR   A5U5C2, PROA_MYCTA ;  P65788, PROA_MYCTU ;  A0PU04, PROA_MYCUA ;
DR   A1TC11, PROA_MYCVP ;  Q3IP72, PROA_NATPD ;  B9L9A2, PROA_NAUPA ;
DR   Q5F8D3, PROA_NEIG1 ;  B4RLE6, PROA_NEIG2 ;  A9LYY9, PROA_NEIM0 ;
DR   Q9JUK8, PROA_NEIMA ;  Q9JZG3, PROA_NEIMB ;  A1KTV4, PROA_NEIMF ;
DR   Q0AEA6, PROA_NITEC ;  Q820I7, PROA_NITEU ;  Q1QQT7, PROA_NITHX ;
DR   Q2YBP9, PROA_NITMU ;  Q3J7T1, PROA_NITOC ;  A6Q3B4, PROA_NITSB ;
DR   Q3SVI0, PROA_NITWN ;  Q5Z025, PROA_NOCFA ;  A1SHP5, PROA_NOCSJ ;
DR   B2IZ89, PROA_NOSP7 ;  Q8YV15, PROA_NOSS1 ;  Q2GCB4, PROA_NOVAD ;
DR   Q8CUQ4, PROA_OCEIH ;  A6WXS2, PROA_OCHA4 ;  Q04FB2, PROA_OENOB ;
DR   B6JD19, PROA_OLICO ;  B1ZMC1, PROA_OPITP ;  A6LE74, PROA_PARD8 ;
DR   A1BAM3, PROA_PARDP ;  A7HT65, PROA_PARL1 ;  Q9CM98, PROA_PASMU ;
DR   C6DCX4, PROA_PECCP ;  Q3A1E0, PROA_PELCD ;  Q3B2U3, PROA_PELLD ;
DR   B4SG68, PROA_PELPB ;  A1AUT0, PROA_PELPD ;  A5CZ28, PROA_PELTS ;
DR   C0QS00, PROA_PERMH ;  A9BJ18, PROA_PETMO ;  Q7N7B1, PROA_PHOLL ;
DR   Q6LTX2, PROA_PHOPR ;  A1VTR9, PROA_POLNA ;  Q122S5, PROA_POLSJ ;
DR   A4SVE2, PROA_POLSQ ;  Q6A9H6, PROA_PROAC ;  A3PBW4, PROA_PROM0 ;
DR   A2C148, PROA_PROM1 ;  A8G3V6, PROA_PROM2 ;  A2CAS7, PROA_PROM3 ;
DR   A2BVQ3, PROA_PROM5 ;  Q31BU4, PROA_PROM9 ;  Q7VBM1, PROA_PROMA ;
DR   B4EUV1, PROA_PROMH ;  Q7V8C3, PROA_PROMM ;  Q7V293, PROA_PROMP ;
DR   A2BQ71, PROA_PROMS ;  Q46LW0, PROA_PROMT ;  A4SFP8, PROA_PROVI ;
DR   Q48DL4, PROA_PSE14 ;  A6V0A3, PROA_PSEA7 ;  B7V8A7, PROA_PSEA8 ;
DR   Q02SH4, PROA_PSEAB ;  Q9HX20, PROA_PSEAE ;  Q1I4F0, PROA_PSEE4 ;
DR   Q4K5F9, PROA_PSEF5 ;  C3K2M9, PROA_PSEFS ;  Q3IEY7, PROA_PSEHT ;
DR   A4XYY4, PROA_PSEMY ;  A5W9J6, PROA_PSEP1 ;  Q3K693, PROA_PSEPF ;
DR   B0KJY5, PROA_PSEPG ;  Q88DL4, PROA_PSEPK ;  B1J133, PROA_PSEPW ;
DR   Q87VV6, PROA_PSESM ;  Q4ZN73, PROA_PSEU2 ;  A4VR07, PROA_PSEU5 ;
DR   Q4FUZ5, PROA_PSYA2 ;  Q1QDZ7, PROA_PSYCK ;  A1SYT9, PROA_PSYIN ;
DR   A5WH78, PROA_PSYWF ;  Q1LJ33, PROA_RALME ;  B2UC98, PROA_RALPJ ;
DR   Q8XVT6, PROA_RALSO ;  B3PRZ5, PROA_RHIE6 ;  Q2K2X4, PROA_RHIEC ;
DR   Q1MA74, PROA_RHIL3 ;  Q98EZ5, PROA_RHILO ;  B5ZUE5, PROA_RHILW ;
DR   Q92LB2, PROA_RHIME ;  Q7UNV2, PROA_RHOBA ;  Q220P2, PROA_RHOFD ;
DR   Q2J3J6, PROA_RHOP2 ;  Q07V09, PROA_RHOP5 ;  Q6NDE4, PROA_RHOPA ;
DR   Q21D00, PROA_RHOPB ;  Q13DN0, PROA_RHOPS ;  B3Q733, PROA_RHOPT ;
DR   Q2RV06, PROA_RHORT ;  A3PQJ2, PROA_RHOS1 ;  Q3IXX7, PROA_RHOS4 ;
DR   B9KW06, PROA_RHOSK ;  Q0SH62, PROA_RHOSR ;  A7NSB7, PROA_ROSCS ;
DR   Q165Y8, PROA_ROSDO ;  A5URC6, PROA_ROSS1 ;  A1AVH0, PROA_RUTMC ;
DR   Q21FC9, PROA_SACD2 ;  A4F9M1, PROA_SACEN ;  B5EWK6, PROA_SALA4 ;
DR   A8M064, PROA_SALAI ;  A9MNR4, PROA_SALAR ;  Q57ST2, PROA_SALCH ;
DR   B5FJX5, PROA_SALDC ;  B5R4S6, PROA_SALEP ;  B5R5R9, PROA_SALG2 ;
DR   B4T7Q6, PROA_SALHS ;  B4SVW6, PROA_SALNS ;  Q5PF69, PROA_SALPA ;
DR   A9MY02, PROA_SALPB ;  C0Q6U2, PROA_SALPC ;  B5BDP7, PROA_SALPK ;
DR   Q2S354, PROA_SALRD ;  B4TZ91, PROA_SALSV ;  Q8Z932, PROA_SALTI ;
DR   A4X1X0, PROA_SALTO ;  P40861, PROA_SALTY ;  Q9UT44, PROA_SCHPO ;
DR   P17857, PROA_SERMA ;  A8GAD4, PROA_SERP5 ;  A1S8L1, PROA_SHEAM ;
DR   Q12SX8, PROA_SHEDO ;  B0TQC4, PROA_SHEHH ;  Q8EHU1, PROA_SHEON ;
DR   A8H764, PROA_SHEPA ;  B8CKF0, PROA_SHEPW ;  A8FYU6, PROA_SHESH ;
DR   B1KD27, PROA_SHEWM ;  B2U3T4, PROA_SHIB3 ;  Q325P3, PROA_SHIBS ;
DR   Q32J27, PROA_SHIDS ;  Q0T7R6, PROA_SHIF8 ;  Q83SH9, PROA_SHIFL ;
DR   Q3Z594, PROA_SHISS ;  Q5LRY6, PROA_SILPO ;  Q1GHC8, PROA_SILST ;
DR   A6UDV8, PROA_SINMW ;  Q2NVE9, PROA_SODGM ;  A9GVS8, PROA_SORC5 ;
DR   Q1GVM0, PROA_SPHAL ;  A5V8T0, PROA_SPHWW ;  Q3K395, PROA_STRA1 ;
DR   Q8E783, PROA_STRA3 ;  Q8E1R9, PROA_STRA5 ;  Q82C81, PROA_STRAW ;
DR   Q9RDK1, PROA_STRCO ;  B4U4K6, PROA_STREM ;  A8AX77, PROA_STRGC ;
DR   B1VXE5, PROA_STRGG ;  Q8DVM9, PROA_STRMU ;  Q99YJ8, PROA_STRP1 ;
DR   Q04KZ2, PROA_STRP2 ;  P0DD20, PROA_STRP3 ;  B5E435, PROA_STRP4 ;
DR   Q5XAL0, PROA_STRP6 ;  C1C6R4, PROA_STRP7 ;  Q8NZX9, PROA_STRP8 ;
DR   Q1JAG3, PROA_STRPB ;  Q1JKL4, PROA_STRPC ;  Q1J5F6, PROA_STRPF ;
DR   A2RD38, PROA_STRPG ;  B1IBA0, PROA_STRPI ;  B8ZP35, PROA_STRPJ ;
DR   Q48RY7, PROA_STRPM ;  Q97R94, PROA_STRPN ;  P0DD21, PROA_STRPQ ;
DR   B2IP88, PROA_STRPS ;  B5XML5, PROA_STRPZ ;  Q8DQ60, PROA_STRR6 ;
DR   A4W028, PROA_STRS2 ;  A3CMT1, PROA_STRSV ;  A4VTT5, PROA_STRSY ;
DR   Q5LY84, PROA_STRT1 ;  Q5M2U1, PROA_STRT2 ;  Q03J03, PROA_STRTD ;
DR   P96489, PROA_STRTR ;  B9DV79, PROA_STRU0 ;  C1CDS9, PROA_STRZJ ;
DR   C1CK18, PROA_STRZP ;  C1CRW1, PROA_STRZT ;  Q30SG0, PROA_SULDN ;
DR   A6QB48, PROA_SULNB ;  B2V9F3, PROA_SULSY ;  Q67LC2, PROA_SYMTH ;
DR   Q2LU85, PROA_SYNAS ;  Q31KX4, PROA_SYNE7 ;  A0LPG2, PROA_SYNFM ;
DR   Q2JQB4, PROA_SYNJA ;  Q2JN71, PROA_SYNJB ;  B1XLA4, PROA_SYNP2 ;
DR   Q5N0Z7, PROA_SYNP6 ;  A5GJS5, PROA_SYNPW ;  Q7U654, PROA_SYNPX ;
DR   A5GSH0, PROA_SYNR3 ;  Q0I8Z0, PROA_SYNS3 ;  Q3AYD4, PROA_SYNS9 ;
DR   Q3AKU8, PROA_SYNSC ;  Q0AWJ6, PROA_SYNWW ;  P54902, PROA_SYNY3 ;
DR   C5BNN0, PROA_TERTT ;  Q8DKU1, PROA_THEEB ;  Q47MW1, PROA_THEFY ;
DR   Q9WYC9, PROA_THEMA ;  A5IKB6, PROA_THEP1 ;  B0K9C5, PROA_THEP3 ;
DR   B0K0T2, PROA_THEPX ;  B1L9J9, PROA_THESQ ;  P54903, PROA_THET2 ;
DR   Q5SH02, PROA_THET8 ;  Q8RAE5, PROA_THETN ;  B5YK66, PROA_THEYD ;
DR   Q31IE5, PROA_THICR ;  Q3SG61, PROA_THIDA ;  C4LBK4, PROA_TOLAT ;
DR   P74935, PROA_TREPA ;  B2S2U7, PROA_TREPS ;  Q112S1, PROA_TRIEI ;
DR   A1WGI4, PROA_VEREI ;  A5CXP4, PROA_VESOH ;  A5F602, PROA_VIBC3 ;
DR   Q9KPT9, PROA_VIBCH ;  Q5E6W0, PROA_VIBF1 ;  B5FBJ5, PROA_VIBFM ;
DR   Q87RU9, PROA_VIBPA ;  B7VJB0, PROA_VIBSL ;  Q8DF94, PROA_VIBVU ;
DR   Q7MN58, PROA_VIBVY ;  Q7M8Z4, PROA_WOLSU ;  Q8PK35, PROA_XANAC ;
DR   Q3BSJ1, PROA_XANC5 ;  Q4UVI0, PROA_XANC8 ;  B0RS59, PROA_XANCB ;
DR   Q8P8K3, PROA_XANCP ;  Q2P2G1, PROA_XANOM ;  B2SHW6, PROA_XANOP ;
DR   Q5GZF2, PROA_XANOR ;  B2I7L2, PROA_XYLF2 ;  Q9PEM3, PROA_XYLFA ;
DR   B0U208, PROA_XYLFM ;  Q87EK9, PROA_XYLFT ;  P54885, PROA_YEAST ;
DR   A1JNX6, PROA_YERE8 ;  A7FLI1, PROA_YERP3 ;  Q1C4E7, PROA_YERPA ;
DR   B2K6Q4, PROA_YERPB ;  Q8ZC09, PROA_YERPE ;  A9R2X0, PROA_YERPG ;
DR   Q1CLC6, PROA_YERPN ;  A4TPK0, PROA_YERPP ;  Q66DY8, PROA_YERPS ;
DR   B1JIH2, PROA_YERPY ;  Q5NLX5, PROA_ZYMMO ;
//
ID   1.2.1.42
DE   Hexadecanal dehydrogenase (acylating).
AN   Fatty acyl-CoA reductase.
CA   Hexadecanal + CoA + NAD(+) = hexadecanoyl-CoA + NADH.
CC   -!- Also acts, more slowly, on octadecanoyl-CoA.
//
ID   1.2.1.43
DE   Formate dehydrogenase (NADP(+)).
CA   Formate + NADP(+) = CO(2) + NADPH.
CF   Iron; Selenium; Tungsten.
//
ID   1.2.1.44
DE   Cinnamoyl-CoA reductase.
CA   Cinnamaldehyde + CoA + NADP(+) = cinnamoyl-CoA + NADPH.
CC   -!- Also acts on a number of substituted cinnamoyl esters of coenzyme A.
//
ID   1.2.1.45
DE   Transferred entry: 1.1.1.312.
//
ID   1.2.1.46
DE   Formaldehyde dehydrogenase.
CA   Formaldehyde + NAD(+) + H(2)O = formate + NADH.
PR   PROSITE; PDOC00058;
DR   Q9HTE3, FADH_PSEAE ;  P46154, FADH_PSEPU ;
//
ID   1.2.1.47
DE   4-trimethylammoniobutyraldehyde dehydrogenase.
CA   4-trimethylammoniobutanal + NAD(+) + H(2)O = 4-trimethylammoniobutanoate
CA   + NADH.
DR   Q2KJH9, AL9A1_BOVIN;  P49189, AL9A1_HUMAN;  Q9JLJ2, AL9A1_MOUSE;
DR   Q29228, AL9A1_PIG  ;  Q5R8A4, AL9A1_PONAB;  Q9JLJ3, AL9A1_RAT  ;
//
ID   1.2.1.48
DE   Long-chain-aldehyde dehydrogenase.
CA   A long-chain aldehyde + NAD(+) + H(2)O = a long-chain acid anion + NADH.
CC   -!- The best substrate is dodecylaldehyde.
//
ID   1.2.1.49
DE   2-oxoaldehyde dehydrogenase (NADP(+)).
AN   Alpha-ketoaldehyde dehydrogenase.
AN   Methylglyoxal dehydrogenase.
CA   A 2-oxoaldehyde + NADP(+) + H(2)O = a 2-oxo acid + NADPH.
CC   -!- Not identical with EC 1.2.1.23.
//
ID   1.2.1.50
DE   Long-chain-fatty-acyl-CoA reductase.
AN   Acyl-CoA reductase.
CA   A long-chain aldehyde + CoA + NADP(+) = a long-chain acyl-CoA + NADPH.
CC   -!- Together with EC 6.2.1.19 forms a fatty acid reductase system which
CC       produces the substrate of EC 1.14.14.3, thus being part of the
CC       bacterial luciferase system.
DR   Q03324, LUXC1_PHOLE;  P29236, LUXC2_PHOLE;  Q7N577, LUXC_PHOLL ;
DR   P23113, LUXC_PHOLU ;  P19841, LUXC_PHOPO ;  P12748, LUXC_VIBFI ;
DR   P08639, LUXC_VIBHA ;
//
ID   1.2.1.51
DE   Pyruvate dehydrogenase (NADP(+)).
AN   Pyruvate:NADP(+) oxidoreductase.
CA   Pyruvate + CoA + NADP(+) = acetyl-CoA + CO(2) + NADPH.
CC   -!- The Euglena enzyme can also use FAD or methyl viologen as acceptor,
CC       more slowly.
CC   -!- Inhibited by oxygen.
DR   Q968X7, PNO_CRYPV  ;  Q94IN5, PNO_EUGGR  ;
//
ID   1.2.1.52
DE   Oxoglutarate dehydrogenase (NADP(+)).
CA   2-oxoglutarate + CoA + NADP(+) = succinyl-CoA + CO(2) + NADPH.
CC   -!- The Euglena enzyme can also use NAD(+) as acceptor, but more slowly.
//
ID   1.2.1.53
DE   4-hydroxyphenylacetaldehyde dehydrogenase.
CA   4-hydroxyphenylacetaldehyde + NAD(+) + H(2)O = 4-hydroxyphenylacetate +
CA   NADH.
CC   -!- With EC 4.2.1.87, brings about the metabolism of octopamine in
CC       Pseudomonas.
//
ID   1.2.1.54
DE   Gamma-guanidinobutyraldehyde dehydrogenase.
CA   4-guanidinobutanal + NAD(+) + H(2)O = 4-guanidinobutanoate + NADH.
CC   -!- Involved in the degradation of arginine in Pseudomonas putida (cf.
CC       EC 1.2.1.19).
//
ID   1.2.1.55
DE   Transferred entry: 1.1.1.279.
//
ID   1.2.1.56
DE   Transferred entry: 1.1.1.280.
//
ID   1.2.1.57
DE   Butanal dehydrogenase.
CA   Butanal + CoA + NAD(P)(+) = butanoyl-CoA + NAD(P)H.
CC   -!- Also acts on acetaldehyde, but more slowly.
//
ID   1.2.1.58
DE   Phenylglyoxylate dehydrogenase (acylating).
CA   Phenylglyoxylate + NAD(+) + CoA = benzoyl-S-CoA + CO(2) + NADH.
CF   FAD; Iron-sulfur; Thiamine diphosphate.
CC   -!- The enzyme from Azoarcus evansii is specific for phenylglyoxylate.
CC   -!- 2-oxoisovalerate is oxidized at 15% of the rate for phenylglyoxylate.
CC   -!- Also reduces viologen dyes.
//
ID   1.2.1.59
DE   Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+)) (phosphorylating).
AN   NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase.
AN   Triosephosphate dehydrogenase (NAD(P)(+)).
AN   Triosephosphate dehydrogenase (NAD(P)).
CA   D-glyceraldehyde 3-phosphate + phosphate + NAD(P)(+) = 3-phospho-D-
CA   glyceroyl phosphate + NAD(P)H.
CC   -!- NAD(+) and NADP(+) can be used as cofactors with similar efficiency,
CC       unlike EC 1.2.1.12 and EC 1.2.1.13, which are NAD(+)- and NADP(+)-
CC       dependent, respectively.
PR   PROSITE; PDOC00069;
DR   P58837, G3P1_METAC ;  Q46AH5, G3P1_METBF ;  O34425, G3P2_BACSU ;
DR   P58838, G3P2_METAC ;  Q465K9, G3P2_METBF ;  P80505, G3P2_SYNY3 ;
DR   O09452, G3PA_GUITH ;  Q9YFS9, G3P_AERPE  ;  O28542, G3P_ARCFU  ;
DR   Q5V061, G3P_HALMA  ;  B0R2M2, G3P_HALS3  ;  Q9HSS7, G3P_HALSA  ;
DR   Q48335, G3P_HALVA  ;  A2BLC6, G3P_HYPBU  ;  A6UUN9, G3P_META3  ;
DR   A7IB57, G3P_METB6  ;  P19314, G3P_METBR  ;  Q12XM4, G3P_METBU  ;
DR   P10618, G3P_METFE  ;  P19315, G3P_METFO  ;  Q2FNA2, G3P_METHJ  ;
DR   Q58546, G3P_METJA  ;  P58839, G3P_METKA  ;  A4FZL2, G3P_METM5  ;
DR   A9A6M9, G3P_METM6  ;  A6VIW4, G3P_METM7  ;  Q8PTD3, G3P_METMA  ;
DR   A3CYG8, G3P_METMJ  ;  Q6M0E6, G3P_METMP  ;  A5ULT9, G3P_METS3  ;
DR   A4YHA5, G3P_METS5  ;  Q2NEN0, G3P_METST  ;  O27090, G3P_METTH  ;
DR   A6URW1, G3P_METVS  ;  Q3IUT3, G3P_NATPD  ;  Q6L125, G3P_PICTO  ;
DR   Q9V1P1, G3P_PYRAB  ;  Q8ZWK7, G3P_PYRAE  ;  A4WIW2, G3P_PYRAR  ;
DR   A3MTU1, G3P_PYRCJ  ;  P61879, G3P_PYRFU  ;  O59494, G3P_PYRHO  ;
DR   A1RV79, G3P_PYRIL  ;  Q5JHB5, G3P_PYRKO  ;  P61880, G3P_PYRWO  ;
DR   Q4J940, G3P_SULAC  ;  C3N6F0, G3P_SULIA  ;  C4KHW5, G3P_SULIK  ;
DR   C3MQN0, G3P_SULIL  ;  C3MWN0, G3P_SULIM  ;  C3NGT6, G3P_SULIN  ;
DR   C3NEV8, G3P_SULIY  ;  P39460, G3P_SULSO  ;  Q971K2, G3P_SULTO  ;
DR   Q9HJ69, G3P_THEAC  ;  B1YD06, G3P_THENV  ;  B6YUU0, G3P_THEON  ;
DR   C6A312, G3P_THESM  ;  Q97BJ8, G3P_THEVO  ;
//
ID   1.2.1.60
DE   5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase.
AN   Carboxymethylhydroxymuconic semialdehyde dehydrogenase.
CA   5-carboxymethyl-2-hydroxymuconate semialdehyde + H(2)O + NAD(+) =
CA   5-carboxymethyl-2-hydroxymuconate + NADH.
CC   -!- Involved in the tyrosine degradation pathway in Arthrobacter sp.
//
ID   1.2.1.61
DE   4-hydroxymuconic-semialdehyde dehydrogenase.
CA   4-hydroxymuconic semialdehyde + NAD(+) + H(2)O = maleylacetate + NADH.
CC   -!- Involved in the 4-nitrophenol degradation pathway.
//
ID   1.2.1.62
DE   4-formylbenzenesulfonate dehydrogenase.
CA   4-formylbenzenesulfonate + NAD(+) + H(2)O = 4-sulfobenzoate + NADH.
CC   -!- Involved in the toluene-4-sulfonate degradation pathway.
//
ID   1.2.1.63
DE   6-oxohexanoate dehydrogenase.
CA   6-oxohexanoate + NADP(+) + H(2)O = adipate + NADPH.
CC   -!- Last step in the cyclohexanol degradation pathway in Acinetobacter
CC       sp.
//
ID   1.2.1.64
DE   4-hydroxybenzaldehyde dehydrogenase.
AN   p-hydroxybenzaldehyde dehydrogenase.
CA   4-hydroxybenzaldehyde + NAD(+) + H(2)O = 4-hydroxybenzoate + NADH.
CC   -!- Involved in the toluene degradation pathway in Pseudomonas mendocina.
//
ID   1.2.1.65
DE   Salicylaldehyde dehydrogenase.
CA   Salicylaldehyde + NAD(+) + H(2)O = salicylate + NADH.
CC   -!- Involved in the naphthalene degradation pathway in some bacteria.
PR   PROSITE; PDOC00068;
DR   P0A391, NAHF_PSEPU ;  P0A390, NAHF_PSEU8 ;
//
ID   1.2.1.66
DE   Transferred entry: 1.1.1.306.
//
ID   1.2.1.67
DE   Vanillin dehydrogenase.
CA   Vanillin + NAD(+) + H(2)O = vanillate + NADH.
//
ID   1.2.1.68
DE   Coniferyl-aldehyde dehydrogenase.
CA   Coniferyl aldehyde + H(2)O + NAD(P)(+) = ferulate + NAD(P)H.
CC   -!- Also oxidizes other aromatic aldehydes, but not aliphatic aldehydes.
DR   Q9A777, CALB_CAUCR ;  Q9I6C8, CALB_PSEAE ;  O86447, CALB_PSEUH ;
//
ID   1.2.1.69
DE   Fluoroacetaldehyde dehydrogenase.
CA   Fluoroacetaldehyde + NAD(+) + H(2)O = fluoroacetate + NADH.
CC   -!- The enzyme from Streptomyces cattleya has a high affinity for
CC       fluoroacetate and glycolaldehyde but not for acetaldehyde.
//
ID   1.2.1.70
DE   Glutamyl-tRNA reductase.
CA   L-glutamate 1-semialdehyde + NADP(+) + tRNA(Glu) = L-glutamyl-tRNA(Glu) +
CA   NADPH.
CC   -!- Forms part of the pathway for the biosynthesis of 5-aminolevulinate
CC       from glutamate, known as the C5 pathway, which is used in most
CC       eubacteria, and in all archaebacteria, algae and plants.
CC   -!- However, in the alpha-proteobacteria EC 2.3.1.37 is used in an
CC       alternative route to produce the product 5-aminolevulinate from
CC       succinyl-CoA and glycine.
CC   -!- This route is found in the mitochondria of fungi and animals,
CC       organelles that are considered to be derived from an endosymbiotic
CC       alpha-proteobacterium.
CC   -!- Although higher plants do not possess EC 2.3.1.37, the protistan
CC       Euglena gracilis possesses both the C5 pathway and EC 2.3.1.37.
PR   PROSITE; PDOC00608;
DR   Q1ITN7, HEM11_ACIBL;  Q2IJD4, HEM11_ANADE;  A7HA35, HEM11_ANADF;
DR   P42804, HEM11_ARATH;  A9KP81, HEM11_CLOPH;  P93111, HEM11_CUCSA;
DR   A5FLE3, HEM11_FLAJ1;  Q42843, HEM11_HORVU;  A1SE01, HEM11_NOCSJ;
DR   A4WJE1, HEM11_PYRAR;  A3MW83, HEM11_PYRCJ;  Q1INI5, HEM12_ACIBL;
DR   Q2IKT3, HEM12_ANADE;  A7HBF2, HEM12_ANADF;  P49294, HEM12_ARATH;
DR   A9KSC2, HEM12_CLOPH;  P49295, HEM12_CUCSA;  A5FDF9, HEM12_FLAJ1;
DR   Q96563, HEM12_HORVU;  A1SI37, HEM12_NOCSJ;  A4WN38, HEM12_PYRAR;
DR   A3MXT2, HEM12_PYRCJ;  O65796, HEM13_HORVU;  B0BZF9, HEM1_ACAM1 ;
DR   A1TTC3, HEM1_ACIAC ;  Q6F8J3, HEM1_ACIAD ;  B7GYQ4, HEM1_ACIB3 ;
DR   B7I7P6, HEM1_ACIB5 ;  B2HUM8, HEM1_ACIBC ;  B0VTW7, HEM1_ACIBS ;
DR   A3M2X7, HEM1_ACIBT ;  B0V8H2, HEM1_ACIBY ;  A0LRF2, HEM1_ACIC1 ;
DR   A1W4B9, HEM1_ACISJ ;  A3MZC2, HEM1_ACTP2 ;  B3H0R8, HEM1_ACTP7 ;
DR   B0BTQ9, HEM1_ACTPJ ;  A6VND5, HEM1_ACTSZ ;  A0KMZ9, HEM1_AERHH ;
DR   Q9Y9J2, HEM1_AERPE ;  A4SK63, HEM1_AERS4 ;  B2ULP2, HEM1_AKKM8 ;
DR   Q0VS78, HEM1_ALCBS ;  Q0AC03, HEM1_ALHEH ;  B6EHH4, HEM1_ALISL ;
DR   A6TJD3, HEM1_ALKMQ ;  A8MGE1, HEM1_ALKOO ;  B9MRJ1, HEM1_ANATD ;
DR   Q3M6T2, HEM1_ANAVT ;  O67314, HEM1_AQUAE ;  A8ERT8, HEM1_ARCB4 ;
DR   O28304, HEM1_ARCFU ;  Q5P7G6, HEM1_AROAE ;  A1R8A6, HEM1_ARTAT ;
DR   B8HBS2, HEM1_ARTCA ;  A0JYN2, HEM1_ARTS2 ;  A1K442, HEM1_AZOSB ;
DR   A7Z7A7, HEM1_BACA2 ;  C3P9F1, HEM1_BACAA ;  C3L6Z7, HEM1_BACAC ;
DR   A0RJ83, HEM1_BACAH ;  Q81LC5, HEM1_BACAN ;  B7JQ59, HEM1_BACC0 ;
DR   Q72ZW0, HEM1_BACC1 ;  B7IIX7, HEM1_BACC2 ;  C1ETR2, HEM1_BACC3 ;
DR   B7HE98, HEM1_BACC4 ;  B7HQM6, HEM1_BACC7 ;  A7GTE7, HEM1_BACCN ;
DR   B9IZ41, HEM1_BACCQ ;  Q817Q8, HEM1_BACCR ;  Q633X8, HEM1_BACCZ ;
DR   Q9K8F8, HEM1_BACHD ;  Q6HD60, HEM1_BACHK ;  Q65GJ9, HEM1_BACLD ;
DR   Q8GCB0, HEM1_BACME ;  A8FFV4, HEM1_BACP2 ;  Q5WEP3, HEM1_BACSK ;
DR   P16618, HEM1_BACSU ;  A9VIU0, HEM1_BACWK ;  C5C5B0, HEM1_BEUC1 ;
DR   Q2KZZ5, HEM1_BORA1 ;  Q7WQF0, HEM1_BORBR ;  Q7WCE4, HEM1_BORPA ;
DR   Q7VRY3, HEM1_BORPE ;  C0ZAG9, HEM1_BREBN ;  B1YSD6, HEM1_BURA4 ;
DR   Q1BSB3, HEM1_BURCA ;  B1JUS5, HEM1_BURCC ;  A0K438, HEM1_BURCH ;
DR   B4E6U7, HEM1_BURCJ ;  Q0BIP9, HEM1_BURCM ;  A9AJ67, HEM1_BURM1 ;
DR   A3MFT3, HEM1_BURM7 ;  A2RYL1, HEM1_BURM9 ;  Q62DF2, HEM1_BURMA ;
DR   A1UWC8, HEM1_BURMS ;  A3NZS3, HEM1_BURP0 ;  Q3JN88, HEM1_BURP1 ;
DR   A3NE23, HEM1_BURP6 ;  B2JHK7, HEM1_BURP8 ;  B2SZ26, HEM1_BURPP ;
DR   Q63QF1, HEM1_BURPS ;  Q39K17, HEM1_BURS3 ;  Q2SUG3, HEM1_BURTA ;
DR   A4JB51, HEM1_BURVG ;  Q13TU3, HEM1_BURXL ;  A8MAH6, HEM1_CALMQ ;
DR   A4XK04, HEM1_CALS8 ;  A7ZD34, HEM1_CAMC1 ;  A7GYU7, HEM1_CAMC5 ;
DR   A0RNT0, HEM1_CAMFF ;  A7I1R7, HEM1_CAMHC ;  A8FKW5, HEM1_CAMJ8 ;
DR   A7H4K0, HEM1_CAMJD ;  Q9PHX2, HEM1_CAMJE ;  A1VYQ1, HEM1_CAMJJ ;
DR   Q5HVM4, HEM1_CAMJR ;  B9KGB2, HEM1_CAMLR ;  Q3ACT4, HEM1_CARHZ ;
DR   A0RXF8, HEM1_CENSY ;  A9WIS2, HEM1_CHLAA ;  Q5L782, HEM1_CHLAB ;
DR   B8G817, HEM1_CHLAD ;  Q3AQF4, HEM1_CHLCH ;  Q824W1, HEM1_CHLCV ;
DR   Q252N9, HEM1_CHLFF ;  B3EIN2, HEM1_CHLL2 ;  Q9PLR2, HEM1_CHLMU ;
DR   P28462, HEM1_CHLP8 ;  B3EPK1, HEM1_CHLPB ;  A1BHD5, HEM1_CHLPD ;
DR   Q9Z7J1, HEM1_CHLPN ;  B9LKR5, HEM1_CHLSY ;  B0B8N8, HEM1_CHLT2 ;
DR   B3QWI0, HEM1_CHLT3 ;  Q3KL32, HEM1_CHLTA ;  B0BAB7, HEM1_CHLTB ;
DR   Q93ST4, HEM1_CHLTE ;  O84669, HEM1_CHLTR ;  Q1QXC7, HEM1_CHRSD ;
DR   Q7P1Y3, HEM1_CHRVO ;  A8AG01, HEM1_CITK8 ;  A5CNH4, HEM1_CLAM3 ;
DR   B0RBM5, HEM1_CLAMS ;  Q97MU6, HEM1_CLOAB ;  A6LSY3, HEM1_CLOB8 ;
DR   B2UXC6, HEM1_CLOBA ;  B2TPD9, HEM1_CLOBB ;  Q59292, HEM1_CLOJO ;
DR   B9DZF9, HEM1_CLOK1 ;  A5N5Y0, HEM1_CLOK5 ;  A0Q2B3, HEM1_CLONN ;
DR   Q0TQG2, HEM1_CLOP1 ;  P0C2E3, HEM1_CLOPE ;  Q0ST14, HEM1_CLOPS ;
DR   Q897K9, HEM1_CLOTE ;  A3DIE8, HEM1_CLOTH ;  Q47Y92, HEM1_COLP3 ;
DR   C3PKG1, HEM1_CORA7 ;  Q6NJK1, HEM1_CORDI ;  Q8FSF8, HEM1_COREF ;
DR   A4QB58, HEM1_CORGB ;  P0C543, HEM1_CORGL ;  Q4JSX4, HEM1_CORJK ;
DR   B1VEJ5, HEM1_CORU7 ;  A9KGY4, HEM1_COXBN ;  A9N9K1, HEM1_COXBR ;
DR   P47846, HEM1_COXBU ;  Q0K6G3, HEM1_CUPNH ;  Q46WT0, HEM1_CUPPJ ;
DR   B1WQ09, HEM1_CYAA5 ;  B8HR03, HEM1_CYAP4 ;  B7KI42, HEM1_CYAP7 ;
DR   B7K1R5, HEM1_CYAP8 ;  P48077, HEM1_CYAPA ;  Q11Y93, HEM1_CYTH3 ;
DR   Q479R3, HEM1_DECAR ;  Q1IWG2, HEM1_DEIGD ;  Q9RRE5, HEM1_DEIRA ;
DR   B8FLI1, HEM1_DESAA ;  C6BV55, HEM1_DESAD ;  B1I4J1, HEM1_DESAP ;
DR   B8IZD9, HEM1_DESDA ;  Q30ZS4, HEM1_DESDG ;  B8G2M3, HEM1_DESHD ;
DR   Q24VC7, HEM1_DESHY ;  C4XPF2, HEM1_DESMR ;  Q6AIM2, HEM1_DESPS ;
DR   A4J6H8, HEM1_DESRM ;  Q72C23, HEM1_DESVH ;  Q9KW52, HEM1_DESVM ;
DR   A1VDW9, HEM1_DESVV ;  A5EWV4, HEM1_DICNV ;  A7ZKY4, HEM1_ECO24 ;
DR   B7UQ98, HEM1_ECO27 ;  B7MKB2, HEM1_ECO45 ;  B7LGX1, HEM1_ECO55 ;
DR   P0A6X2, HEM1_ECO57 ;  B5YXM8, HEM1_ECO5E ;  B7NUX6, HEM1_ECO7I ;
DR   B7MTZ4, HEM1_ECO81 ;  B7LXC5, HEM1_ECO8A ;  C4ZTQ1, HEM1_ECOBW ;
DR   B1XAQ1, HEM1_ECODH ;  A7ZZE6, HEM1_ECOHS ;  A1AAD7, HEM1_ECOK1 ;
DR   Q0TIG0, HEM1_ECOL5 ;  Q8FI03, HEM1_ECOL6 ;  B1IU83, HEM1_ECOLC ;
DR   P0A6X1, HEM1_ECOLI ;  B7N421, HEM1_ECOLU ;  B6I9S5, HEM1_ECOSE ;
DR   B1LH90, HEM1_ECOSM ;  Q1RCM8, HEM1_ECOUT ;  C5B813, HEM1_EDWI9 ;
DR   A4WBC7, HEM1_ENT38 ;  A7MKC0, HEM1_ENTS8 ;  Q6D552, HEM1_ERWCT ;
DR   B2VEH8, HEM1_ERWT9 ;  B7LSI0, HEM1_ESCF3 ;  B1YJV2, HEM1_EXIS2 ;
DR   C4L4J5, HEM1_EXISA ;  A6GVP1, HEM1_FLAPJ ;  Q0RS17, HEM1_FRAAA ;
DR   B0TX36, HEM1_FRAP2 ;  Q2JFS1, HEM1_FRASC ;  A8LDG7, HEM1_FRASN ;
DR   Q14JR2, HEM1_FRAT1 ;  A7NE97, HEM1_FRATF ;  Q2A1P9, HEM1_FRATH ;
DR   B2SFF5, HEM1_FRATM ;  A0Q845, HEM1_FRATN ;  Q0BKE7, HEM1_FRATO ;
DR   Q5NIA9, HEM1_FRATT ;  A4IWC0, HEM1_FRATW ;  Q8R687, HEM1_FUSNN ;
DR   B5EBG7, HEM1_GEOBB ;  Q5KWK4, HEM1_GEOKA ;  B3E2H8, HEM1_GEOLS ;
DR   Q39QM8, HEM1_GEOMG ;  B9M417, HEM1_GEOSF ;  Q747I2, HEM1_GEOSL ;
DR   C6DYY7, HEM1_GEOSM ;  A4IRG7, HEM1_GEOTN ;  A5GCW3, HEM1_GEOUR ;
DR   Q7NLA8, HEM1_GLOVI ;  A0M6C1, HEM1_GRAFK ;  B8F4X6, HEM1_HAEPS ;
DR   Q0I3Q6, HEM1_HAES1 ;  B0UU02, HEM1_HAES2 ;  Q2SL96, HEM1_HAHCH ;
DR   A1WVQ7, HEM1_HALHL ;  Q5V1I8, HEM1_HALMA ;  B0R6C0, HEM1_HALS3 ;
DR   Q9HP72, HEM1_HALSA ;  Q18F28, HEM1_HALWD ;  Q17W63, HEM1_HELAH ;
DR   Q7VFF1, HEM1_HELHP ;  Q9ZGG6, HEM1_HELMO ;  B6JKH0, HEM1_HELP2 ;
DR   B5ZA06, HEM1_HELPG ;  Q1CUR3, HEM1_HELPH ;  Q9ZMJ5, HEM1_HELPJ ;
DR   B2US71, HEM1_HELPS ;  P56125, HEM1_HELPY ;  A9B543, HEM1_HERA2 ;
DR   A4G1N3, HEM1_HERAR ;  A2BJB7, HEM1_HYPBU ;  Q5QV08, HEM1_IDILO ;
DR   A8A9U3, HEM1_IGNH4 ;  A6SUF7, HEM1_JANMA ;  A6W5L7, HEM1_KINRD ;
DR   B5XW50, HEM1_KLEP3 ;  A6TAP0, HEM1_KLEP7 ;  B2GL19, HEM1_KOCRD ;
DR   A5VM68, HEM1_LACRD ;  B2G9H5, HEM1_LACRJ ;  Q1MRJ8, HEM1_LAWIP ;
DR   Q5X2V4, HEM1_LEGPA ;  A5IED6, HEM1_LEGPC ;  Q5ZT30, HEM1_LEGPH ;
DR   Q5WUB2, HEM1_LEGPL ;  Q6AHF6, HEM1_LEIXX ;  Q92BF7, HEM1_LISIN ;
DR   C1KVK4, HEM1_LISMC ;  Q71ZB1, HEM1_LISMF ;  B8DHJ1, HEM1_LISMH ;
DR   Q8Y6X4, HEM1_LISMO ;  A0AJ06, HEM1_LISW6 ;  B1HVD8, HEM1_LYSSC ;
DR   B9E745, HEM1_MACCJ ;  A0LDT6, HEM1_MAGSM ;  Q65SX9, HEM1_MANSM ;
DR   A1U368, HEM1_MARAV ;  A6W1C3, HEM1_MARMS ;  A6UT22, HEM1_META3 ;
DR   Q8TT60, HEM1_METAC ;  A7I7P5, HEM1_METB6 ;  Q46CH3, HEM1_METBF ;
DR   Q12WM5, HEM1_METBU ;  Q60A20, HEM1_METCA ;  Q1GYE9, HEM1_METFK ;
DR   Q2FTL0, HEM1_METHJ ;  Q60172, HEM1_METJA ;  Q9UXR8, HEM1_METKA ;
DR   A2SQU1, HEM1_METLZ ;  A4G0A1, HEM1_METM5 ;  A9A8K3, HEM1_METM6 ;
DR   A6VI77, HEM1_METM7 ;  Q8PW60, HEM1_METMA ;  A3CU63, HEM1_METMJ ;
DR   Q6M130, HEM1_METMP ;  A2SD47, HEM1_METPP ;  A5ULU4, HEM1_METS3 ;
DR   A4YD89, HEM1_METS5 ;  Q2NEH4, HEM1_METST ;  O27093, HEM1_METTH ;
DR   P42809, HEM1_METTM ;  A0B577, HEM1_METTP ;  A6UR78, HEM1_METVS ;
DR   B0JKN4, HEM1_MICAN ;  C5CB93, HEM1_MICLC ;  Q2RJ25, HEM1_MOOTA ;
DR   A0QLI1, HEM1_MYCA1 ;  B1MHI6, HEM1_MYCA9 ;  P64329, HEM1_MYCBO ;
DR   A1KFY5, HEM1_MYCBP ;  C1AKI9, HEM1_MYCBT ;  A4T341, HEM1_MYCGI ;
DR   P46724, HEM1_MYCLE ;  Q73SS1, HEM1_MYCPA ;  A0QR17, HEM1_MYCS2 ;
DR   A3PUA3, HEM1_MYCSJ ;  A1UAP7, HEM1_MYCSK ;  Q1BE87, HEM1_MYCSS ;
DR   A5TZN9, HEM1_MYCTA ;  P64328, HEM1_MYCTU ;  A0PW28, HEM1_MYCUA ;
DR   A1T3D2, HEM1_MYCVP ;  Q1D8Z9, HEM1_MYXXD ;  Q3ING1, HEM1_NATPD ;
DR   B2A1G4, HEM1_NATTJ ;  Q9ZHD6, HEM1_NEIG1 ;  B4RNE5, HEM1_NEIG2 ;
DR   A9M2B8, HEM1_NEIM0 ;  P0A0T7, HEM1_NEIMA ;  P56994, HEM1_NEIMB ;
DR   P0A0T8, HEM1_NEIMC ;  A1KSI5, HEM1_NEIMF ;  Q0AHU2, HEM1_NITEC ;
DR   Q82TH3, HEM1_NITEU ;  Q2Y5P2, HEM1_NITMU ;  Q3JDR3, HEM1_NITOC ;
DR   A6Q3S5, HEM1_NITSB ;  Q5YP69, HEM1_NOCFA ;  B2J5E4, HEM1_NOSP7 ;
DR   O08393, HEM1_NOSS1 ;  Q8EPM7, HEM1_OCEIH ;  A2Z928, HEM1_ORYSI ;
DR   P0C587, HEM1_ORYSJ ;  O69108, HEM1_PAEMA ;  Q6MEC8, HEM1_PARUW ;
DR   P95525, HEM1_PASMU ;  C6DHY2, HEM1_PECCP ;  Q3A008, HEM1_PELCD ;
DR   Q3B2Z6, HEM1_PELLD ;  B4SFI3, HEM1_PELPB ;  A1AUE9, HEM1_PELPD ;
DR   A5D3L4, HEM1_PELTS ;  C0QS44, HEM1_PERMH ;  Q7N587, HEM1_PHOLL ;
DR   Q6LNB3, HEM1_PHOPR ;  Q6L0J9, HEM1_PICTO ;  A1VKB7, HEM1_POLNA ;
DR   Q12F85, HEM1_POLSJ ;  A4SV44, HEM1_POLSQ ;  B4S921, HEM1_PROA2 ;
DR   Q6AB02, HEM1_PROAC ;  A3PCH6, HEM1_PROM0 ;  A2C1K4, HEM1_PROM1 ;
DR   A8G4E6, HEM1_PROM2 ;  A2CAB8, HEM1_PROM3 ;  A9BAR3, HEM1_PROM4 ;
DR   A2BW63, HEM1_PROM5 ;  Q31BA9, HEM1_PROM9 ;  Q7VCA1, HEM1_PROMA ;
DR   B4EVR6, HEM1_PROMH ;  Q7V809, HEM1_PROMM ;  Q7V1T7, HEM1_PROMP ;
DR   A2BQQ3, HEM1_PROMS ;  Q46LG2, HEM1_PROMT ;  A4SFJ7, HEM1_PROVI ;
DR   Q48MV5, HEM1_PSE14 ;  Q15SQ8, HEM1_PSEA6 ;  A6VC62, HEM1_PSEA7 ;
DR   B7V0L2, HEM1_PSEA8 ;  Q02G08, HEM1_PSEAB ;  P42807, HEM1_PSEAE ;
DR   Q1IEX2, HEM1_PSEE4 ;  Q4K694, HEM1_PSEF5 ;  C3KDC5, HEM1_PSEFS ;
DR   Q3IK96, HEM1_PSEHT ;  A4XR60, HEM1_PSEMY ;  A5VYG4, HEM1_PSEP1 ;
DR   Q3K6W8, HEM1_PSEPF ;  B0KNE3, HEM1_PSEPG ;  Q88PW6, HEM1_PSEPK ;
DR   B1JEP7, HEM1_PSEPW ;  Q888C2, HEM1_PSESM ;  Q4ZXW8, HEM1_PSEU2 ;
DR   A4VPC0, HEM1_PSEU5 ;  Q4FVA9, HEM1_PSYA2 ;  Q1QED0, HEM1_PSYCK ;
DR   A1SV88, HEM1_PSYIN ;  A5WC75, HEM1_PSYWF ;  Q8ZYV6, HEM1_PYRAE ;
DR   A1RQP7, HEM1_PYRIL ;  Q1LIF4, HEM1_RALME ;  Q8XVD1, HEM1_RALSO ;
DR   A9WPH1, HEM1_RENSM ;  Q7UKZ2, HEM1_RHOBA ;  C0ZUV4, HEM1_RHOE4 ;
DR   Q21YY8, HEM1_RHOFD ;  C1AZ44, HEM1_RHOOB ;  Q2RWE2, HEM1_RHORT ;
DR   Q0SF26, HEM1_RHOSR ;  A7NKU4, HEM1_ROSCS ;  A5UU33, HEM1_ROSS1 ;
DR   Q1AUK2, HEM1_RUBXD ;  A1AX01, HEM1_RUTMC ;  Q21FM2, HEM1_SACD2 ;
DR   A4FPY4, HEM1_SACEN ;  B5F4H5, HEM1_SALA4 ;  A8LZI9, HEM1_SALAI ;
DR   A9MPA0, HEM1_SALAR ;  Q57NN4, HEM1_SALCH ;  B5FU18, HEM1_SALDC ;
DR   B5R3J8, HEM1_SALEP ;  B5R923, HEM1_SALG2 ;  B4TKA5, HEM1_SALHS ;
DR   B4SUG3, HEM1_SALNS ;  Q5PCR0, HEM1_SALPA ;  A9MW03, HEM1_SALPB ;
DR   B5BI74, HEM1_SALPK ;  Q2S2A5, HEM1_SALRD ;  B4TXU3, HEM1_SALSV ;
DR   P0A1Q7, HEM1_SALTI ;  A4X1U1, HEM1_SALTO ;  P0A1Q6, HEM1_SALTY ;
DR   A8GDA2, HEM1_SERP5 ;  A1S8R3, HEM1_SHEAM ;  B8E816, HEM1_SHEB2 ;
DR   A3D0G0, HEM1_SHEB5 ;  A6WSF1, HEM1_SHEB8 ;  A9L2D5, HEM1_SHEB9 ;
DR   Q12QR9, HEM1_SHEDO ;  Q087I5, HEM1_SHEFN ;  B0TR28, HEM1_SHEHH ;
DR   A3QH31, HEM1_SHELP ;  Q8EAR2, HEM1_SHEON ;  A8H7A6, HEM1_SHEPA ;
DR   A4Y3J7, HEM1_SHEPC ;  B8CQV3, HEM1_SHEPW ;  A0KT87, HEM1_SHESA ;
DR   A8FYZ1, HEM1_SHESH ;  Q0HFC7, HEM1_SHESM ;  Q0HYK9, HEM1_SHESR ;
DR   A1RNE2, HEM1_SHESW ;  B1KDU4, HEM1_SHEWM ;  B2TZV8, HEM1_SHIB3 ;
DR   Q31ZQ3, HEM1_SHIBS ;  Q32GZ7, HEM1_SHIDS ;  Q0T5I5, HEM1_SHIF8 ;
DR   Q83RP1, HEM1_SHIFL ;  Q3Z0S8, HEM1_SHISS ;  Q2NRS3, HEM1_SODGM ;
DR   Q022E5, HEM1_SOLUE ;  A9FDP5, HEM1_SORC5 ;  A7X393, HEM1_STAA1 ;
DR   A6U2E0, HEM1_STAA2 ;  Q2FG64, HEM1_STAA3 ;  Q2FXQ9, HEM1_STAA8 ;
DR   A5ITJ7, HEM1_STAA9 ;  Q2YTB7, HEM1_STAAB ;  Q5HFA0, HEM1_STAAC ;
DR   A6QHK6, HEM1_STAAE ;  P64330, HEM1_STAAM ;  P64331, HEM1_STAAN ;
DR   Q6GG33, HEM1_STAAR ;  Q6G8Q3, HEM1_STAAS ;  A8Z2J3, HEM1_STAAT ;
DR   P64332, HEM1_STAAW ;  B9DND0, HEM1_STACT ;  Q5HNN1, HEM1_STAEQ ;
DR   Q8CNY6, HEM1_STAES ;  Q4L711, HEM1_STAHJ ;  Q49YA4, HEM1_STAS1 ;
DR   Q82E77, HEM1_STRAW ;  Q9WX15, HEM1_STRCO ;  B4SKS9, HEM1_STRM5 ;
DR   B2FQ15, HEM1_STRMK ;  A3CL77, HEM1_STRSV ;  Q4JAM9, HEM1_SULAC ;
DR   Q30S94, HEM1_SULDN ;  C3MZS1, HEM1_SULIA ;  C4KJ02, HEM1_SULIK ;
DR   C3MJ24, HEM1_SULIL ;  C3MYE2, HEM1_SULIM ;  C3NF67, HEM1_SULIN ;
DR   C3N844, HEM1_SULIY ;  A6Q7Y8, HEM1_SULNB ;  Q980U7, HEM1_SULSO ;
DR   B2V771, HEM1_SULSY ;  Q976H4, HEM1_SULTO ;  Q2LQU3, HEM1_SYNAS ;
DR   Q31QY3, HEM1_SYNE7 ;  A0LIM5, HEM1_SYNFM ;  Q2JWU6, HEM1_SYNJA ;
DR   Q2JJG8, HEM1_SYNJB ;  B1XLK6, HEM1_SYNP2 ;  Q5N3B4, HEM1_SYNP6 ;
DR   A5GLB0, HEM1_SYNPW ;  Q7U769, HEM1_SYNPX ;  A5GTE8, HEM1_SYNR3 ;
DR   Q0I9I2, HEM1_SYNS3 ;  Q3AXK4, HEM1_SYNS9 ;  Q3AK73, HEM1_SYNSC ;
DR   P28463, HEM1_SYNY3 ;  C5BSZ7, HEM1_TERTT ;  Q9HKR0, HEM1_THEAC ;
DR   Q8DI53, HEM1_THEEB ;  Q47LA6, HEM1_THEFY ;  A6LKW9, HEM1_THEM4 ;
DR   B1YBN0, HEM1_THENV ;  B9L0Q1, HEM1_THERP ;  Q72IJ0, HEM1_THET2 ;
DR   Q5SI68, HEM1_THET8 ;  Q97B68, HEM1_THEVO ;  B5YJZ3, HEM1_THEYD ;
DR   Q31IN7, HEM1_THICR ;  Q3SG11, HEM1_THIDA ;  Q117I4, HEM1_TRIEI ;
DR   Q83H91, HEM1_TROW8 ;  Q83FI9, HEM1_TROWT ;  Q0W5T5, HEM1_UNCMA ;
DR   A1WI55, HEM1_VEREI ;  A5CW97, HEM1_VESOH ;  A5F697, HEM1_VIBC3 ;
DR   Q9KQ24, HEM1_VIBCH ;  C3LPI5, HEM1_VIBCM ;  Q5E6T4, HEM1_VIBF1 ;
DR   B5FBW9, HEM1_VIBFM ;  A7MY81, HEM1_VIBHB ;  Q87RN5, HEM1_VIBPA ;
DR   B7VKH2, HEM1_VIBSL ;  Q8DFF8, HEM1_VIBVU ;  Q7MMY7, HEM1_VIBVY ;
DR   Q8D2K8, HEM1_WIGBR ;  Q7MBG5, HEM1_WOLSU ;  Q8PNU4, HEM1_XANAC ;
DR   Q3BX06, HEM1_XANC5 ;  Q4URB7, HEM1_XANC8 ;  B0RUA4, HEM1_XANCB ;
DR   P42808, HEM1_XANCH ;  Q8PC67, HEM1_XANCP ;  Q2NZW3, HEM1_XANOM ;
DR   B2SQN6, HEM1_XANOP ;  Q5GWR0, HEM1_XANOR ;  B2IA84, HEM1_XYLF2 ;
DR   Q9PA72, HEM1_XYLFA ;  B0U5Z2, HEM1_XYLFM ;  Q87A18, HEM1_XYLFT ;
DR   A1JRU4, HEM1_YERE8 ;  A7FIG2, HEM1_YERP3 ;  Q1C855, HEM1_YERPA ;
DR   Q8ZEX9, HEM1_YERPE ;  A9QZ09, HEM1_YERPG ;  Q1CJK2, HEM1_YERPN ;
DR   A4TJN8, HEM1_YERPP ;  Q66AX6, HEM1_YERPS ;
//
ID   1.2.1.71
DE   Succinylglutamate-semialdehyde dehydrogenase.
AN   N-succinylglutamate 5-semialdehyde dehydrogenase.
AN   SGSD.
AN   Succinylglutamic semialdehyde dehydrogenase.
CA   N-succinyl-L-glutamate 5-semialdehyde + NAD(+) + H(2)O = N-succinyl-L-
CA   glutamate + NADH.
CC   -!- This is the fourth enzyme in the arginine succinyltransferase (AST)
CC       pathway for the catabolism of arginine.
CC   -!- This pathway converts the carbon skeleton of arginine into glutamate,
CC       with the concomitant production of ammonia and conversion of
CC       succinyl-CoA into succinate and CoA.
CC   -!- The five enzymes involved in this pathway are EC 2.3.1.109,
CC       EC 3.5.3.23, EC 2.6.1.11, EC 1.2.1.71 and EC 3.5.1.96.
PR   PROSITE; PDOC00068;
DR   Q9AAL5, ASTD1_CAUCR;  Q3IFT7, ASTD1_PSEHT;  Q12QD2, ASTD1_SHEDO;
DR   Q9A7W2, ASTD2_CAUCR;  Q3IC91, ASTD2_PSEHT;  Q12JA9, ASTD2_SHEDO;
DR   Q6FCQ0, ASTD_ACIAD ;  A0KN18, ASTD_AERHH ;  A4SK35, ASTD_AERS4 ;
DR   B6EML5, ASTD_ALISL ;  B1YW19, ASTD_BURA4 ;  Q1BXP1, ASTD_BURCA ;
DR   B1JYT5, ASTD_BURCC ;  A0K608, ASTD_BURCH ;  B4ECZ8, ASTD_BURCJ ;
DR   Q0BGV0, ASTD_BURCM ;  A9AD19, ASTD_BURM1 ;  Q62LN5, ASTD_BURMA ;
DR   A1V675, ASTD_BURMS ;  A3NXG2, ASTD_BURP0 ;  Q3JQC6, ASTD_BURP1 ;
DR   A3NBM7, ASTD_BURP6 ;  Q63SD7, ASTD_BURPS ;  Q39I25, ASTD_BURS3 ;
DR   Q2SXN9, ASTD_BURTA ;  A4JCW0, ASTD_BURVG ;  Q141D3, ASTD_BURXL ;
DR   B0T8I8, ASTD_CAUSK ;  Q1QTQ7, ASTD_CHRSD ;  Q7NXX7, ASTD_CHRVO ;
DR   A8AHD8, ASTD_CITK8 ;  Q488Y0, ASTD_COLP3 ;  A7ZML4, ASTD_ECO24 ;
DR   B7USC7, ASTD_ECO27 ;  B7MAV7, ASTD_ECO45 ;  B7L6M0, ASTD_ECO55 ;
DR   Q7ADE6, ASTD_ECO57 ;  B5YQ33, ASTD_ECO5E ;  B7NT31, ASTD_ECO7I ;
DR   B7MVM5, ASTD_ECO81 ;  B7M1F8, ASTD_ECO8A ;  C4ZZA2, ASTD_ECOBW ;
DR   B1XGK7, ASTD_ECODH ;  A8A0T8, ASTD_ECOHS ;  Q0TH84, ASTD_ECOL5 ;
DR   Q8FH01, ASTD_ECOL6 ;  B1IPI4, ASTD_ECOLC ;  P76217, ASTD_ECOLI ;
DR   B7N582, ASTD_ECOLU ;  B6IBG6, ASTD_ECOSE ;  B1LDY5, ASTD_ECOSM ;
DR   Q1RB47, ASTD_ECOUT ;  A4W9J7, ASTD_ENT38 ;  A7MNV8, ASTD_ENTS8 ;
DR   B2VJX8, ASTD_ERWT9 ;  B7LQ46, ASTD_ESCF3 ;  Q2SKP1, ASTD_HAHCH ;
DR   Q5QVX3, ASTD_IDILO ;  A6T7T5, ASTD_KLEP7 ;  Q5X4K4, ASTD_LEGPA ;
DR   A5ICK3, ASTD_LEGPC ;  Q5ZUT5, ASTD_LEGPH ;  Q5WVZ4, ASTD_LEGPL ;
DR   A1U5W8, ASTD_MARAV ;  Q2G9T9, ASTD_NOVAD ;  Q7N2G9, ASTD_PHOLL ;
DR   Q6LVE5, ASTD_PHOPR ;  Q48G19, ASTD_PSE14 ;  Q15Y60, ASTD_PSEA6 ;
DR   O50174, ASTD_PSEAE ;  Q1I6Z5, ASTD_PSEE4 ;  Q4K837, ASTD_PSEF5 ;
DR   C3JXY7, ASTD_PSEFS ;  A4XWE7, ASTD_PSEMY ;  A5W0D5, ASTD_PSEP1 ;
DR   Q3K885, ASTD_PSEPF ;  B0KR47, ASTD_PSEPG ;  Q88EI4, ASTD_PSEPK ;
DR   B1JCH3, ASTD_PSEPW ;  Q885J7, ASTD_PSESM ;  Q4ZQH8, ASTD_PSEU2 ;
DR   B5F7J0, ASTD_SALA4 ;  A9MFG0, ASTD_SALAR ;  B5FJD6, ASTD_SALDC ;
DR   B5QWI8, ASTD_SALEP ;  B5RAZ9, ASTD_SALG2 ;  B4TGE2, ASTD_SALHS ;
DR   B4T3Z6, ASTD_SALNS ;  Q5PHC0, ASTD_SALPA ;  A9N276, ASTD_SALPB ;
DR   C0Q6X8, ASTD_SALPC ;  B5BA70, ASTD_SALPK ;  B4TUC3, ASTD_SALSV ;
DR   Q8Z6G1, ASTD_SALTI ;  Q8ZPV0, ASTD_SALTY ;  A8GFQ3, ASTD_SERP5 ;
DR   B8EBC2, ASTD_SHEB2 ;  A3D039, ASTD_SHEB5 ;  A6WST7, ASTD_SHEB8 ;
DR   A9L3U4, ASTD_SHEB9 ;  Q07XY1, ASTD_SHEFN ;  B0TU38, ASTD_SHEHH ;
DR   Q8EJ54, ASTD_SHEON ;  A8H8E0, ASTD_SHEPA ;  A4Y344, ASTD_SHEPC ;
DR   B8CIT6, ASTD_SHEPW ;  A0KST2, ASTD_SHESA ;  A8FRE9, ASTD_SHESH ;
DR   A1RNU4, ASTD_SHESW ;  B1KDF2, ASTD_SHEWM ;  B2U3C8, ASTD_SHIB3 ;
DR   Q321N8, ASTD_SHIBS ;  Q32G88, ASTD_SHIDS ;  Q0T4V3, ASTD_SHIF8 ;
DR   Q7UCI7, ASTD_SHIFL ;  A9EN94, ASTD_SORC5 ;  Q1GV29, ASTD_SPHAL ;
DR   A5F529, ASTD_VIBC3 ;  Q9KNW4, ASTD_VIBCH ;  C3LRS7, ASTD_VIBCM ;
DR   Q5E2G9, ASTD_VIBF1 ;  B5FBM2, ASTD_VIBFM ;  A7MX96, ASTD_VIBHB ;
DR   Q87L22, ASTD_VIBPA ;  B7VLI4, ASTD_VIBSL ;  Q8DCS9, ASTD_VIBVU ;
DR   Q7MH21, ASTD_VIBVY ;  Q1C8A9, ASTD_YERPA ;  B2K296, ASTD_YERPB ;
DR   Q9ZC68, ASTD_YERPE ;  A9QZ61, ASTD_YERPG ;  A4TJU5, ASTD_YERPP ;
DR   Q66B19, ASTD_YERPS ;  B1JMD1, ASTD_YERPY ;
//
ID   1.2.1.72
DE   Erythrose-4-phosphate dehydrogenase.
AN   E4P dehydrogenase.
AN   E4PDH.
AN   Erythrose 4-phosphate dehydrogenase.
CA   D-erythrose 4-phosphate + NAD(+) + H(2)O = 4-phosphoerythronate + NADH.
CC   -!- Was originally thought to be an EC 1.2.1.12, but this has since been
CC       disproved, as glyceraldehyde 3-phosphate is not a substrate.
CC   -!- Forms part of the pyridoxal-5'-phosphate coenzyme biosynthesis
CC       pathway in Escherichia coli, along with EC 1.1.1.290, EC 2.6.1.52,
CC       EC 1.1.1.262, EC 2.6.99.2 and EC 1.4.3.5.
PR   PROSITE; PDOC00069;
DR   A0KGD2, E4PD_AERHH ;  A4SRF2, E4PD_AERS4 ;  B6EMW1, E4PD_ALISL ;
DR   B4RWC5, E4PD_ALTMD ;  A8APE1, E4PD_CITK8 ;  Q47XD5, E4PD_COLP3 ;
DR   A7ZR35, E4PD_ECO24 ;  B7UHW9, E4PD_ECO27 ;  B7MMA9, E4PD_ECO45 ;
DR   B7LFI3, E4PD_ECO55 ;  P0A9B8, E4PD_ECO57 ;  B5YQB9, E4PD_ECO5E ;
DR   B7NHY6, E4PD_ECO7I ;  B7MZM0, E4PD_ECO81 ;  B7LYU4, E4PD_ECO8A ;
DR   C5A0J7, E4PD_ECOBW ;  B1XEL0, E4PD_ECODH ;  A8A467, E4PD_ECOHS ;
DR   A1AFB1, E4PD_ECOK1 ;  Q0TDS9, E4PD_ECOL5 ;  P0A9B7, E4PD_ECOL6 ;
DR   B1IT76, E4PD_ECOLC ;  P0A9B6, E4PD_ECOLI ;  B7N7H3, E4PD_ECOLU ;
DR   B6I761, E4PD_ECOSE ;  B1LDD2, E4PD_ECOSM ;  Q1R7A6, E4PD_ECOUT ;
DR   C5BAU7, E4PD_EDWI9 ;  A4WE72, E4PD_ENT38 ;  A7MJQ2, E4PD_ENTS8 ;
DR   Q6D086, E4PD_ERWCT ;  B2VF24, E4PD_ERWT9 ;  B7LPD5, E4PD_ESCF3 ;
DR   Q5QVL6, E4PD_IDILO ;  B5XUB7, E4PD_KLEP3 ;  A6TDT2, E4PD_KLEP7 ;
DR   C6DFH8, E4PD_PECCP ;  Q7N7Z6, E4PD_PHOLL ;  Q6LMN0, E4PD_PHOPR ;
DR   B4EUH7, E4PD_PROMH ;  Q15QK3, E4PD_PSEA6 ;  Q3ILL8, E4PD_PSEHT ;
DR   A1SVN9, E4PD_PSYIN ;  B5F5J5, E4PD_SALA4 ;  A9MRF0, E4PD_SALAR ;
DR   Q57K44, E4PD_SALCH ;  B5FUI3, E4PD_SALDC ;  B5QXJ7, E4PD_SALEP ;
DR   B5RE31, E4PD_SALG2 ;  B4THF4, E4PD_SALHS ;  B4T5H2, E4PD_SALNS ;
DR   Q5PJI5, E4PD_SALPA ;  A9N3Q6, E4PD_SALPB ;  C0PY46, E4PD_SALPC ;
DR   B5BFN5, E4PD_SALPK ;  B4TV39, E4PD_SALSV ;  Q8XGA4, E4PD_SALTI ;
DR   Q7CPU5, E4PD_SALTY ;  A1S9A4, E4PD_SHEAM ;  B8E5U5, E4PD_SHEB2 ;
DR   Q12QA4, E4PD_SHEDO ;  Q087Q7, E4PD_SHEFN ;  B0TUC0, E4PD_SHEHH ;
DR   A3QAX7, E4PD_SHELP ;  Q8EIB2, E4PD_SHEON ;  A8H0M9, E4PD_SHEPA ;
DR   A4Y3R9, E4PD_SHEPC ;  B8CU41, E4PD_SHEPW ;  A0L0K7, E4PD_SHESA ;
DR   Q0HM63, E4PD_SHESM ;  Q0HRM3, E4PD_SHESR ;  A1RN69, E4PD_SHESW ;
DR   B2U0U3, E4PD_SHIB3 ;  Q31WI6, E4PD_SHIBS ;  Q32BY7, E4PD_SHIDS ;
DR   Q0T0X3, E4PD_SHIF8 ;  P0A9B9, E4PD_SHIFL ;  Q3YXU5, E4PD_SHISS ;
DR   C4L9J3, E4PD_TOLAT ;  A5F9G1, E4PD_VIBC3 ;  P0C6C2, E4PD_VIBCH ;
DR   Q5E7R0, E4PD_VIBF1 ;  B5F9T4, E4PD_VIBFM ;  A7MTQ2, E4PD_VIBHB ;
DR   Q87LL0, E4PD_VIBPA ;  Q8DCA1, E4PD_VIBVU ;  Q7MHL0, E4PD_VIBVY ;
DR   A1JPR1, E4PD_YERE8 ;  Q1CB62, E4PD_YERPA ;  Q7CGS4, E4PD_YERPE ;
DR   Q1CEY2, E4PD_YERPN ;  Q666Q0, E4PD_YERPS ;
//
ID   1.2.1.73
DE   Sulfoacetaldehyde dehydrogenase.
CA   2-sulfoacetaldehyde + H(2)O + NAD(+) = sulfoacetate + NADH.
CC   -!- Part of a bacterial pathway that can utilize the amino group of
CC       taurine as a sole source of nitrogen for growth.
CC   -!- At physiological concentrations, NAD(+) cannot be replaced by
CC       NADP(+).
CC   -!- Specific for sulfoacetaldehyde, as formaldehyde, acetaldehyde,
CC       betaine aldehyde, propanal, glyceraldehyde, phosphonoaldehyde,
CC       glyoxylate, glycolaldehyde and 2-oxobutyrate are not substrates.
PR   PROSITE; PS00070;
//
ID   1.2.1.74
DE   Abietadienal dehydrogenase.
CA   Abietadienal + H(2)O + NAD(+) = abietate + NADH.
CC   -!- Abietic acid is the principle component of conifer resin.
CC   -!- This enzyme catalyzes the last step of the pathway of abietic acid
CC       biosynthesis in Abies grandis (grand fir).
CC   -!- The activity has been demonstrated in cell-free stem extracts of
CC       A.grandis, was present in the cytoplasm, and required NAD(+) as
CC       cofactor.
CC   -!- The enzyme is expressed constitutively at a high level, and is not
CC       inducible by wounding of the plant tissue.
//
ID   1.2.1.75
DE   Malonyl CoA reductase (malonate semialdehyde-forming).
AN   Malonyl CoA reductase (NADP).
AN   NADP-dependent malonyl CoA reductase.
CA   Malonate semialdehyde + coenzyme A + NADP(+) = malonyl-CoA + NADPH.
CF   Magnesium.
CC   -!- Catalyzes the reduction of malonyl-CoA to malonate semialdehyde,
CC       a key step in the 3-hydroxypropanoate and the
CC       3-hydroxypropanoate/4-hydroxybutyrate cycles, autotrophic CO(2)
CC       fixation pathways found in some green non-sulfur phototrophic
CC       bacteria and some thermoacidophilic archaea, respectively.
CC   -!- The enzyme from Sulfolobus tokodaii has been purified, and found to
CC       contain one RNA molecule per two subunits.
CC   -!- The enzyme from Chloroflexus aurantiacus is bifunctional, and also
CC       catalyzes the next reaction in the pathway, EC 1.1.1.298.
//
ID   1.2.1.76
DE   Succinate-semialdehyde dehydrogenase (acetylating).
AN   Coenzyme-A-dependent succinate-semialdehyde dehydrogenase.
AN   Succinyl-CoA reductase.
CA   Succinate semialdehyde + coenzyme A + NADP(+) = succinyl-CoA + NADPH.
CC   -!- Catalyzes the NADPH-dependent reduction of succinyl-CoA to succinate
CC       semialdehyde.
CC   -!- The enzyme has been described in Clostridium kluyveri, where it
CC       participates in succinate fermentation, and in Metallosphaera sedula,
CC       where it participates in the 3-hydroxypropanoate/4-hydroxybutyrate
CC       cycle, an autotrophic CO(2) fixation pathway found in some
CC       thermoacidophilic archaea.
PR   PROSITE; PDOC00058;
DR   P38947, SUCD_CLOK5 ;
//
ID   1.2.1.77
DE   3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP(+)).
AN   3,4-dehydroadipyl-CoA semialdehyde dehydrogenase.
CA   Cis-3,4-dehydroadipyl-CoA semialdehyde + NADP(+) + H(2)O = cis-3,4-
CA   dehydroadipyl-CoA + NADPH.
CC   -!- This enzyme catalyzes a step in the aerobic benzoyl-coenzyme A
CC       catabolic pathway in Azoarcus evansii and Burkholderia xenovorans.
CC   -!- Formerly EC 1.2.1.n1.
PR   PROSITE; PDOC00068;
DR   Q84HH8, BOXD_AZOEV ;
//
ID   1.2.1.78
DE   2-formylbenzoate dehydrogenase.
AN   2-carboxybenzaldehyde dehydrogenase.
CA   2-formylbenzoate + NAD(+) + H(2)O = phthalate + NADH.
CC   -!- The enzyme is involved in phenanthrene degradation.
PR   PROSITE; PDOC00068;
//
ID   1.2.1.79
DE   Succinate-semialdehyde dehydrogenase (NADP(+)).
CA   Succinate semialdehyde + NADP(+) + H(2)O = succinate + NADPH.
CC   -!- This enzyme participates in the degradation of glutamate and
CC       4-aminobutyrate.
CC   -!- It is similar to EC 1.2.1.24 and EC 1.2.1.16 but is specific for
CC       NADP(+).
CC   -!- The enzyme from Escherichia coli is 20-fold more active with NADP(+)
CC       than NAD(+).
DR   A0QMB9, GABD1_MYCA1;  A1KF54, GABD1_MYCBP;  O69497, GABD1_MYCLE;
DR   Q73TP5, GABD1_MYCPA;  A5TYV9, GABD1_MYCTA;  P71989, GABD1_MYCTU;
DR   A0PN13, GABD1_MYCUA;  Q7TZP3, GABD2_MYCBO;  A1KJE8, GABD2_MYCBP;
DR   A0R4Q0, GABD2_MYCS2;  A5U390, GABD2_MYCTA;  P96417, GABD2_MYCTU;
DR   A0PST9, GABD2_MYCUA;  P94428, GABD_BACSU ;  O32507, GABD_DEIRA ;
DR   P25526, GABD_ECOLI ;  P55653, GABD_RHISN ;  Q55585, GABD_SYNY3 ;
//
ID   1.2.1.80
DE   Long-chain acyl-[acyl-carrier-protein] reductase.
AN   Fatty acyl-[acyl-carrier-protein] reductase.
CA   A long-chain aldehyde + [acyl-carrier protein] + NAD(P)(+) = a long-chain
CA   acyl-[acyl-carrier protein] + NAD(P)H.
CF   Magnesium.
CC   -!- Catalyzes the reaction in the opposite direction.
CC   -!- This enzyme, purified from the cyanobacterium Synechococcus elongatus
CC       PCC 7942, catalyzes the NAD(P)H-dependent reduction of an activated
CC       fatty acid (acyl-[acp]) to the corresponding aldehyde.
CC   -!- Together with EC 4.1.99.5, it is involved in alkane biosynthesis.
CC   -!- The natural substrates of the enzyme are C16 to C18 activated fatty
CC       acids.
//
ID   1.2.1.81
DE   Sulfoacetaldehyde dehydrogenase (acylating).
CA   2-sulfoacetaldehyde + CoA + NADP(+) = sulfoacetyl-CoA + NADPH.
CC   -!- The enzyme is involved in degradation of sulfoacetate.
CC   -!- In this pathway the reaction is catalyzed in the reverse direction.
CC   -!- The enzyme is specific for sulfoacetaldehyde and NADP(+).
//
ID   1.2.1.n1
DE   Transferred entry: 1.2.1.77.
//
ID   1.2.1.n2
DE   Fatty acyl-CoA reductase.
AN   Hexadecanal dehydrogenase (acylating, NADP dependent).
CA   Hexadecanal + CoA + NADP(+) = hexadecanoyl-CoA + NADPH.
DR   Q6F7B8, ACR1_ACIAD ;  P94129, ACR1_ACIBI ;  Q39152, FACR1_ARATH;
DR   Q5ZM72, FACR1_CHICK;  A1ZAI5, FACR1_DROME;  Q8WVX9, FACR1_HUMAN;
DR   Q922J9, FACR1_MOUSE;  Q5R834, FACR1_PONAB;  Q66H50, FACR1_RAT  ;
DR   Q7ZXF5, FACR1_XENLA;  Q08891, FACR2_ARATH;  Q0P5J1, FACR2_BOVIN;
DR   A1ZAI3, FACR2_DROME;  Q96K12, FACR2_HUMAN;  Q7TNT2, FACR2_MOUSE;
DR   Q93ZB9, FACR3_ARATH;  Q960W6, FACR3_DROME;  Q9LXN3, FACR4_ARATH;
DR   Q0WRB0, FACR5_ARATH;  B9TSP7, FACR6_ARATH;  Q9FMQ9, FACR7_ARATH;
DR   Q1PEI6, FACR8_ARATH;
//
ID   1.2.2.1
DE   Formate dehydrogenase (cytochrome).
CA   Formate + 2 ferricytochrome b1 = CO(2) + 2 ferrocytochrome b1 + 2 H(+).
//
ID   1.2.2.2
DE   Deleted entry.
//
ID   1.2.2.3
DE   Formate dehydrogenase (cytochrome c-553).
CA   Formate + ferricytochrome c-553 = CO(2) + ferrocytochrome c-553.
CC   -!- Saccharomyces cerevisiae cytochrome c, ferricyanide and phenazine
CC       methosulfate can act as acceptors.
//
ID   1.2.2.4
DE   Carbon-monoxide dehydrogenase (cytochrome b-561).
AN   Carbon monoxide oxidase.
AN   Carbon monoxide oxygenase (cytochrome b-561).
AN   Carbon monoxide:methylene blue oxidoreductase.
CA   CO + H(2)O + 2 ferricytochrome b-561 = CO(2) + 2 H(+) + 2 ferrocytochrome
CA   b-561.
CF   FAD; Iron-sulfur; Molybdopterin cytosine dinucleotide.
CC   -!- Oxygen, methylene blue and iodonitrotetrazolium chloride can act as
CC       nonphysiological electron acceptors.
//
ID   1.2.3.1
DE   Aldehyde oxidase.
AN   Quinoline oxidase.
CA   An aldehyde + H(2)O + O(2) = a carboxylic acid + H(2)O(2).
CF   FAD; Iron-sulfur; Molybdenum.
CC   -!- Also oxidizes quinoline and pyridine derivatives.
CC   -!- May be identical with EC 1.2.3.11.
PR   PROSITE; PDOC00484;
DR   P48034, ADO_BOVIN  ;  Q06278, ADO_HUMAN  ;  Q5FB27, ADO_MACFA  ;
DR   O54754, ADO_MOUSE  ;  P80456, ADO_RABIT  ;  Q9Z0U5, ADO_RAT    ;
DR   Q7G193, ALDO1_ARATH;  Q7XH05, ALDO1_ORYSJ;  Q7G192, ALDO2_ARATH;
DR   Q852M1, ALDO2_ORYSJ;  Q852M2, ALDO3_ORYSJ;  Q7G191, ALDO4_ARATH;
DR   Q69R21, ALDO4_ORYSJ;
//
ID   1.2.3.2
DE   Transferred entry: 1.17.3.2.
//
ID   1.2.3.3
DE   Pyruvate oxidase.
AN   Phosphate-dependent pyruvate oxidase.
AN   Pyruvic oxidase.
CA   Pyruvate + phosphate + O(2) = acetyl phosphate + CO(2) + H(2)O(2).
CF   FAD; Thiamine diphosphate.
CC   -!- Two reducing equivalents are transferred from the resonant
CC       carbanion/enamine forms of 2-hydroxyethyl-thiamine-diphosphate to the
CC       adjacent flavin cofactor, yielding 2-acetyl-thiamine diphosphate
CC       (AcThDP) and reduced flavin.
CC   -!- FADH is reoxidized by O(2) to yield H(2)O(2) and FAD and AcThDP is
CC       cleaved phosphorolytically to acetyl phosphate and thiamine
CC       diphosphate.
PR   PROSITE; PDOC00166;
DR   P37063, POXB_LACPL ;  Q54970, POXB_STRPN ;
//
ID   1.2.3.4
DE   Oxalate oxidase.
CA   Oxalate + O(2) + 2 H(+) = 2 CO(2) + H(2)O(2).
CF   Manganese.
PR   PROSITE; PDOC00597;
DR   P15290, GER2_WHEAT ;  P26759, GER3_WHEAT ;  P45850, OXO1_HORVU ;
DR   P45851, OXO2_HORVU ;
//
ID   1.2.3.5
DE   Glyoxylate oxidase.
CA   Glyoxylate + H(2)O + O(2) = oxalate + H(2)O(2).
//
ID   1.2.3.6
DE   Pyruvate oxidase (CoA-acetylating).
CA   Pyruvate + CoA + O(2) = acetyl-CoA + CO(2) + H(2)O(2).
CF   FAD.
CC   -!- May be identical with EC 1.2.7.1.
//
ID   1.2.3.7
DE   Indole-3-acetaldehyde oxidase.
AN   IAA oxidase.
AN   IAAld oxidase.
AN   Indoleacetaldehyde oxidase.
CA   (Indol-3-yl)acetaldehyde + H(2)O + O(2) = (indol-3-yl)acetate + H(2)O(2).
CF   FAD; Heme; Molybdenum.
CC   -!- Isoform of EC 1.2.3.1.
CC   -!- Has a preference for aldehydes having an indole-ring structure as
CC       substrate.
CC   -!- May play a role in plant hormone biosynthesis as its activity is
CC       higher in the auxin-overproducing mutant, super-root1, than in wild-
CC       type Arabidopsis thaliana.
CC   -!- While (indol-3-yl)acetaldehyde is the preferred substrate, it also
CC       oxidizes indole-3-carbaldehyde and acetaldehyde, but more slowly.
//
ID   1.2.3.8
DE   Pyridoxal oxidase.
CA   Pyridoxal + H(2)O + O(2) = 4-pyridoxate + H(2)O(2).
CF   Molybdenum.
//
ID   1.2.3.9
DE   Aryl-aldehyde oxidase.
CA   An aromatic aldehyde + O(2) + H(2)O = an aromatic carboxylic acid +
CA   H(2)O(2).
CC   -!- Acts on benzaldehyde, vanillin and a number of other aromatic
CC       aldehydes, but not on aliphatic aldehydes or sugars.
//
ID   1.2.3.10
DE   Deleted entry.
//
ID   1.2.3.11
DE   Retinal oxidase.
AN   Retinene oxidase.
CA   Retinal + O(2) + H(2)O = retinoate + H(2)O(2).
CC   -!- May be the same as EC 1.2.3.1.
//
ID   1.2.3.12
DE   Transferred entry: 1.14.13.82.
//
ID   1.2.3.13
DE   4-hydroxyphenylpyruvate oxidase.
CA   2 4-hydroxyphenylpyruvate + O(2) = 2 4-hydroxyphenylacetate + 2 CO(2).
CC   -!- Involved in tyrosine degradation pathway in Arthrobacter sp.
//
ID   1.2.3.14
DE   Abscisic-aldehyde oxidase.
AN   AO-delta.
CA   Abscisic aldehyde + H(2)O + O(2) = abscisate + H(2)O(2).
CC   -!- Acts on both (+)- and (-)-abscisic aldehyde.
CC   -!- Involved in the abscisic-acid biosynthesis pathway in plants, along
CC       with EC 1.1.1.288, EC 1.13.11.51 and EC 1.14.13.93.
CC   -!- While abscisic aldehyde is the best substrate, the enzyme also acts
CC       with indole-3-aldehyde, 1-naphthaldehyde and benzaldehyde as
CC       substrates, but more slowly.
DR   Q7G9P4, ALDO3_ARATH;
//
ID   1.2.4.1
DE   Pyruvate dehydrogenase (acetyl-transferring).
AN   MtPDC (mitochondrial pyruvate dehydogenase complex).
AN   Pyruvate decarboxylase.
AN   Pyruvate dehydrogenase.
AN   Pyruvate dehydrogenase (lipoamide).
AN   Pyruvate dehydrogenase complex.
AN   Pyruvate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-
AN   acetylating).
AN   Pyruvic acid dehydrogenase.
AN   Pyruvic dehydrogenase.
CA   Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine =
CA   [dihydrolipoyllysine-residue acetyltransferase]
CA   S-acetyldihydrolipoyllysine + CO(2).
CF   Thiamine diphosphate.
CC   -!- It is a component (in multiple copies) of the multienzyme pyruvate
CC       dehydrogenase complex in which it is bound to a core of molecules of
CC       EC 2.3.1.12, which also binds multiple copies of EC 1.8.1.4.
CC   -!- It does not act on free lipoamide or lipoyllysine, but only on the
CC       lipoyllysine residue in EC 2.3.1.12.
DR   P10801, ODP1_AZOVI ;  P57301, ODP1_BUCAI ;  Q8K9T9, ODP1_BUCAP ;
DR   Q89AR0, ODP1_BUCBP ;  Q59097, ODP1_CUPNH ;  P0AFG9, ODP1_ECO57 ;
DR   P0AFG8, ODP1_ECOLI ;  P45119, ODP1_HAEIN ;  A0R0B0, ODP1_MYCS2 ;
DR   Q10504, ODP1_MYCTU ;  Q59637, ODP1_PSEAE ;  P52901, ODPA1_ARATH;
DR   Q8H1Y0, ODPA2_ARATH;  P29803, ODPAT_HUMAN;  P35487, ODPAT_MOUSE;
DR   Q06437, ODPAT_RAT  ;  P35485, ODPA_ACHLA ;  P26267, ODPA_ASCSU ;
DR   Q4MTG0, ODPA_BACCE ;  P21881, ODPA_BACSU ;  A7MB35, ODPA_BOVIN ;
DR   P52899, ODPA_CAEEL ;  P49823, ODPA_CANFA ;  Q54C70, ODPA_DICDI ;
DR   P21873, ODPA_GEOSE ;  P08559, ODPA_HUMAN ;  O13366, ODPA_KLULA ;
DR   Q8HXW9, ODPA_MACFA ;  P35486, ODPA_MOUSE ;  P47516, ODPA_MYCGE ;
DR   P75390, ODPA_MYCPN ;  A5A6L0, ODPA_PANTR ;  P52902, ODPA_PEA   ;
DR   P29804, ODPA_PIG   ;  Q5R490, ODPA_PONAB ;  P51267, ODPA_PORPU ;
DR   Q1XDM0, ODPA_PORYE ;  P26284, ODPA_RAT   ;  Q9R9N5, ODPA_RHIME ;
DR   Q1RJX4, ODPA_RICBR ;  Q92IS3, ODPA_RICCN ;  Q4UKQ6, ODPA_RICFE ;
DR   Q9ZDR4, ODPA_RICPR ;  Q68XA9, ODPA_RICTY ;  Q10489, ODPA_SCHPO ;
DR   P52900, ODPA_SMIMA ;  P52903, ODPA_SOLTU ;  Q5HGZ1, ODPA_STAAC ;
DR   P60089, ODPA_STAAM ;  Q820A6, ODPA_STAAN ;  Q6GHZ2, ODPA_STAAR ;
DR   Q6GAC1, ODPA_STAAS ;  P60090, ODPA_STAAW ;  Q5HQ76, ODPA_STAEQ ;
DR   Q8CPN3, ODPA_STAES ;  P16387, ODPA_YEAST ;  O66112, ODPA_ZYMMO ;
DR   P35488, ODPB_ACHLA ;  Q38799, ODPB_ARATH ;  P26269, ODPB_ASCSU ;
DR   P21882, ODPB_BACSU ;  P11966, ODPB_BOVIN ;  O44451, ODPB_CAEEL ;
DR   Q8MA03, ODPB_CHAGL ;  Q1ACL0, ODPB_CHAVU ;  A2CI50, ODPB_CHLAT ;
DR   Q9TLS3, ODPB_CYACA ;  Q85FX1, ODPB_CYAME ;  Q86HX0, ODPB_DICDI ;
DR   P21874, ODPB_GEOSE ;  Q6B8T1, ODPB_GRATL ;  P11177, ODPB_HUMAN ;
DR   Q6ABX8, ODPB_LEIXX ;  P86222, ODPB_MESAU ;  Q9MUR4, ODPB_MESVI ;
DR   Q9D051, ODPB_MOUSE ;  P47515, ODPB_MYCGE ;  P75391, ODPB_MYCPN ;
DR   P52904, ODPB_PEA   ;  Q5RE79, ODPB_PONAB ;  P51266, ODPB_PORPU ;
DR   Q1XDM1, ODPB_PORYE ;  P49432, ODPB_RAT   ;  Q9R9N4, ODPB_RHIME ;
DR   Q1RJX3, ODPB_RICBR ;  Q92IS2, ODPB_RICCN ;  Q4UKQ7, ODPB_RICFE ;
DR   Q9ZDR3, ODPB_RICPR ;  Q68XA8, ODPB_RICTY ;  Q09171, ODPB_SCHPO ;
DR   P81419, ODPB_SOLTU ;  Q5HGZ0, ODPB_STAAC ;  P0A0A1, ODPB_STAAM ;
DR   P99063, ODPB_STAAN ;  Q6GHZ1, ODPB_STAAR ;  Q6GAC0, ODPB_STAAS ;
DR   P0A0A3, ODPB_STAAU ;  P0A0A2, ODPB_STAAW ;  Q5HQ75, ODPB_STAEQ ;
DR   Q8CPN2, ODPB_STAES ;  Q32RS0, ODPB_STAPU ;  P32473, ODPB_YEAST ;
DR   Q32RM2, ODPB_ZYGCR ;  O66113, ODPB_ZYMMO ;  P26268, ODPT_ASCSU ;
//
ID   1.2.4.2
DE   Oxoglutarate dehydrogenase (succinyl-transferring).
AN   2-ketoglutarate dehydrogenase.
AN   2-oxoglutarate dehydrogenase.
AN   2-oxoglutarate: lipoate oxidoreductase.
AN   2-oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-
AN   succinylating).
AN   AKGDH.
AN   Alpha-ketoglutarate dehydrogenase.
AN   Alpha-ketoglutaric acid dehydrogenase.
AN   Alpha-ketoglutaric dehydrogenase.
AN   Alpha-oxoglutarate dehydrogenase.
AN   Ketoglutaric dehydrogenase.
AN   OGDC.
AN   Oxoglutarate decarboxylase.
AN   Oxoglutarate dehydrogenase.
AN   Oxoglutarate dehydrogenase (lipoamide).
CA   2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase]
CA   lipoyllysine = [dihydrolipoyllysine-residue succinyltransferase]
CA   S-succinyldihydrolipoyllysine + CO(2).
CF   Thiamine diphosphate.
CC   -!- It is a component of the multienzyme 2-oxoglutarate dehydrogenase
CC       complex in which multiple copies of it are bound to a core of
CC       molecules of EC 2.3.1.61, which also binds multiple copies of
CC       EC 1.8.1.4.
CC   -!- It does not act on free lipoamide or lipoyllysine, but only on the
CC       lipoyllysine residue in EC 2.3.1.61.
DR   Q23629, DHTK1_CAEEL;  Q5PRA2, DHTK1_DANRE;  Q54VG0, DHTK1_DICDI;
DR   Q9VA02, DHTK1_DROME;  Q96HY7, DHTK1_HUMAN;  A2ATU0, DHTK1_MOUSE;
DR   Q5R7H0, DHTK1_PONAB;  Q4KLP0, DHTK1_RAT  ;  Q6P286, DHTK1_XENLA;
DR   P20707, ODO1_AZOVI ;  A7Z5J9, ODO1_BACA2 ;  C3P487, ODO1_BACAA ;
DR   C3LAU3, ODO1_BACAC ;  Q81TK1, ODO1_BACAN ;  B7JEU9, ODO1_BACC0 ;
DR   Q73BN8, ODO1_BACC1 ;  B7IM94, ODO1_BACC2 ;  C1ELG5, ODO1_BACC3 ;
DR   B7HH19, ODO1_BACC4 ;  B7I0H2, ODO1_BACC7 ;  A7GMD4, ODO1_BACCN ;
DR   B9IU58, ODO1_BACCQ ;  Q81GF2, ODO1_BACCR ;  Q63EB1, ODO1_BACCZ ;
DR   Q9KAT1, ODO1_BACHD ;  Q6HLS8, ODO1_BACHK ;  Q65IH4, ODO1_BACLD ;
DR   A8FE66, ODO1_BACP2 ;  Q5WG56, ODO1_BACSK ;  P23129, ODO1_BACSU ;
DR   A9VJX9, ODO1_BACWK ;  Q148N0, ODO1_BOVIN ;  B2S877, ODO1_BRUA1 ;
DR   Q2YLS2, ODO1_BRUA2 ;  Q57AX5, ODO1_BRUAB ;  A9M8Q9, ODO1_BRUC2 ;
DR   C0RFG8, ODO1_BRUMB ;  Q8YJE4, ODO1_BRUME ;  A5VSQ0, ODO1_BRUO2 ;
DR   B0CIS7, ODO1_BRUSI ;  Q8FYF7, ODO1_BRUSU ;  P57388, ODO1_BUCAI ;
DR   Q8K9N3, ODO1_BUCAP ;  Q89AJ7, ODO1_BUCBP ;  Q623T0, ODO1_CAEBR ;
DR   O61199, ODO1_CAEEL ;  Q8NRC3, ODO1_CORGL ;  P51056, ODO1_COXBU ;
DR   Q59106, ODO1_CUPNH ;  Q54JE4, ODO1_DICDI ;  P0AFG5, ODO1_ECO57 ;
DR   P0AFG4, ODO1_ECOL6 ;  P0AFG3, ODO1_ECOLI ;  C4L3W2, ODO1_EXISA ;
DR   Q5L172, ODO1_GEOKA ;  C5D802, ODO1_GEOSW ;  P45303, ODO1_HAEIN ;
DR   Q02218, ODO1_HUMAN ;  Q72PJ7, ODO1_LEPIC ;  Q8F6S7, ODO1_LEPIN ;
DR   Q60HE2, ODO1_MACFA ;  P86231, ODO1_MESAU ;  Q60597, ODO1_MOUSE ;
DR   Q8CUL8, ODO1_OCEIH ;  A6WXF0, ODO1_OCHA4 ;  Q5RCB8, ODO1_PONAB ;
DR   Q5XI78, ODO1_RAT   ;  Q1RHI4, ODO1_RICBR ;  Q92J42, ODO1_RICCN ;
DR   Q4UKI8, ODO1_RICFE ;  Q9ZDY3, ODO1_RICPR ;  Q68XI7, ODO1_RICTY ;
DR   O74378, ODO1_SCHPO ;  P81895, ODO1_SOLTU ;  A7X295, ODO1_STAA1 ;
DR   A6U1N4, ODO1_STAA2 ;  Q2FH25, ODO1_STAA3 ;  Q2FYM1, ODO1_STAA8 ;
DR   A5ISU5, ODO1_STAA9 ;  Q2YY05, ODO1_STAAB ;  Q5HG06, ODO1_STAAC ;
DR   A6QGW6, ODO1_STAAE ;  Q931R8, ODO1_STAAM ;  Q99U74, ODO1_STAAN ;
DR   Q6GGZ5, ODO1_STAAR ;  Q6G9E8, ODO1_STAAS ;  A8Z3Z0, ODO1_STAAT ;
DR   P0C601, ODO1_STAAU ;  Q8NWR6, ODO1_STAAW ;  Q5HPC6, ODO1_STAEQ ;
DR   Q8CP83, ODO1_STAES ;  Q4L6C4, ODO1_STAHJ ;  Q49XM5, ODO1_STAS1 ;
DR   Q6P6Z8, ODO1_XENLA ;  P20967, ODO1_YEAST ;
//
ID   1.2.4.3
DE   Transferred entry: 1.2.4.4.
//
ID   1.2.4.4
DE   3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring).
AN   2-oxoisocaproate dehydrogenase.
AN   2-oxoisovalerate (lipoate) dehydrogenase.
AN   3-methyl-2-oxobutanoate dehydrogenase (lipoamide).
AN   3-methyl-2-oxobutanoate:lipoamide oxidoreductase (decarboxylating and
AN   acceptor-2-methylpropanoylating).
AN   Alpha-keto-alpha-methylvalerate dehydrogenase.
AN   Alpha-ketoisocaproate dehydrogenase.
AN   Alpha-ketoisocaproic dehydrogenase.
AN   Alpha-ketoisocaproic-alpha-keto-alpha-methylvaleric dehydrogenase.
AN   Alpha-ketoisovalerate dehydrogenase.
AN   Alpha-oxoisocaproate dehydrogenase.
AN   BCKDH.
AN   BCOAD.
AN   Branched chain keto acid dehydrogenase.
AN   Branched-chain (-2-oxoacid) dehydrogenase (BCD).
AN   Branched-chain 2-keto acid dehydrogenase.
AN   Branched-chain 2-oxo acid dehydrogenase.
AN   Branched-chain alpha-keto acid dehydrogenase.
AN   Branched-chain alpha-oxo acid dehydrogenase.
AN   Branched-chain keto acid dehydrogenase.
AN   Branched-chain ketoacid dehydrogenase.
AN   Dehydrogenase, 2-oxoisovalerate (lipoate).
AN   Dehydrogenase, branched chain alpha-keto acid.
CA   3-methyl-2-oxobutanoate + [dihydrolipoyllysine-residue
CA   (2-methylpropanoyl)transferase] lipoyllysine = [dihydrolipoyllysine-
CA   residue (2-methylpropanoyl)transferase]
CA   S-(2-methylpropanoyl)dihydrolipoyllysine + CO(2).
CF   Thiamine diphosphate.
CC   -!- It acts not only on 3-methyl-2-oxobutanaoate, but also on 4-methyl-2-
CC       oxopentanoate and (S)-3-methyl-2-oxopentanoate, so that it acts on
CC       the 2-oxo acids that derive from the action of transaminases on
CC       valine, leucine and isoleucine.
CC   -!- It is a component of the multienzyme 3-methyl-2-oxobutanoate
CC       dehydrogenase complex in which multiple copies of it are bound to a
CC       core of molecules of EC 2.3.1.168, which also binds multiple copies
CC       of EC 1.8.1.4.
CC   -!- It does not act on free lipoamide or lipoyllysine, but only on the
CC       lipoyllysine residue in EC 2.3.1.168.
CC   -!- Formerly EC 1.2.4.3.
DR   P37940, ODBA_BACSU ;  P11178, ODBA_BOVIN ;  Q54M22, ODBA_DICDI ;
DR   P12694, ODBA_HUMAN ;  Q8HXY4, ODBA_MACFA ;  P50136, ODBA_MOUSE ;
DR   A5A6H9, ODBA_PANTR ;  Q9I1M2, ODBA_PSEAE ;  P09060, ODBA_PSEPU ;
DR   P11960, ODBA_RAT   ;  Q72GU1, ODBA_THET2 ;  Q5SLR4, ODBA_THET8 ;
DR   P37941, ODBB_BACSU ;  P21839, ODBB_BOVIN ;  Q55FN7, ODBB_DICDI ;
DR   P21953, ODBB_HUMAN ;  Q6P3A8, ODBB_MOUSE ;  Q9I1M1, ODBB_PSEAE ;
DR   P09061, ODBB_PSEPU ;  P35738, ODBB_RAT   ;  Q72GU2, ODBB_THET2 ;
DR   Q5SLR3, ODBB_THET8 ;
//
ID   1.2.5.1
DE   Pyruvate dehydrogenase (quinone).
AN   Pyruvate dehydrogenase.
AN   Pyruvate dehydrogenase (cytochrome).
AN   Pyruvate oxidase.
CA   Pyruvate + ubiquinone + H(2)O = acetate + CO(2) + ubiquinol.
CF   FAD.
CC   -!- This bacterial enzyme is located on the inner surface of the
CC       cytoplasmic membrane and coupled to the respiratory chain via
CC       ubiquinone.
CC   -!- Does not accept menaquinone.
CC   -!- Activity is greatly enhanced by lipids.
CC   -!- Requires thiamine diphosphate.
CC   -!- The enzyme can also form acetoin.
DR   P07003, POXB_ECOLI ;
//
ID   1.2.7.1
DE   Pyruvate synthase.
AN   Pyruvate oxidoreductase.
AN   Pyruvate synthetase.
AN   Pyruvate:ferredoxin oxidoreductase.
AN   Pyruvic-ferredoxin oxidoreductase.
CA   Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO(2) + 2 reduced
CA   ferredoxin + 2 H(+).
CF   Iron-sulfur; Thiamine diphosphate.
CC   -!- One of four 2-oxoacid oxidoreductases that are differentiated by
CC       their abilities to oxidatively decarboxylatedifferent 2-oxoacids and
CC       form their CoA derivatives (see also EC 1.2.7.3, EC 1.2.7.7 and
CC       EC 1.2.7.8).
DR   P80521, PORA_METBF ;  Q57715, PORA_METJA ;  P56810, PORA_METTH ;
DR   P80900, PORA_METTM ;  Q9UYZ4, PORA_PYRAB ;  Q51804, PORA_PYRFU ;
DR   O73986, PORA_PYRHO ;  O05651, PORA_THEMA ;  P80522, PORB_METBF ;
DR   Q57714, PORB_METJA ;  O27771, PORB_METTH ;  P80901, PORB_METTM ;
DR   Q9UYZ5, PORB_PYRAB ;  Q51805, PORB_PYRFU ;  O58417, PORB_PYRHO ;
DR   Q56317, PORB_THEMA ;  P80523, PORC_METBF ;  Q57717, PORC_METJA ;
DR   O27772, PORC_METTH ;  P80902, PORC_METTM ;  Q9UYY9, PORC_PYRAB ;
DR   P84819, PORC_PYREN ;  Q51799, PORC_PYRFU ;  O58411, PORC_PYRHO ;
DR   Q5JIK2, PORC_PYRKO ;  P84820, PORC_THELI ;  O05650, PORC_THEMA ;
//
ID   1.2.7.2
DE   2-oxobutyrate synthase.
CA   2-oxobutanoate + CoA + 2 oxidized ferredoxin = propanoyl-CoA + CO(2) +
CA   2 reduced ferredoxin + H(+).
//
ID   1.2.7.3
DE   2-oxoglutarate synthase.
AN   2-ketoglutarate ferredoxin oxidoreductase.
AN   2-oxoglutarate ferredoxin oxidoreductase.
AN   Alpha-ketoglutarate synthase.
AN   Alpha-ketoglutarate-ferredoxin oxidoreductase.
AN   KGOR.
CA   2-oxoglutarate + CoA + 2 oxidized ferredoxin = succinyl-CoA + CO(2) +
CA   2 reduced ferredoxin + 2 H(+).
CF   Iron-sulfur; Thiamine diphosphate.
CC   -!- One of four 2-oxoacid oxidoreductases that are differentiated by
CC       their abilities to oxidatively decarboxylate different 2-oxoacids and
CC       form their CoA derivatives (see also EC 1.2.7.1, EC 1.2.7.7 and
CC       EC 1.2.7.8).
CC   -!- Highly specific for 2-oxoglutarate.
CC   -!- Formerly EC 1.2.7.9.
DR   O29781, KORA_ARCFU ;  Q57724, KORA_METJA ;  O27112, KORA_METTH ;
DR   P80904, KORA_METTM ;  O29782, KORB_ARCFU ;  Q57957, KORB_METJA ;
DR   O27113, KORB_METTH ;  P80905, KORB_METTM ;  O29779, KORC_ARCFU ;
DR   Q57956, KORC_METJA ;  O27114, KORC_METTH ;  P80906, KORC_METTM ;
//
ID   1.2.7.4
DE   Carbon-monoxide dehydrogenase (ferredoxin).
CA   CO + H(2)O + 2 oxidized ferredoxin = CO(2) + 2 reduced ferredoxin +
CA   2 H(+).
CF   Iron; Nickel; Zinc.
CC   -!- Methyl viologen can act as acceptor.
CC   -!- The enzyme from Moorella thermoacetica exists as a complex with
CC       EC 2.3.1.169, which catalyzes the overall reaction: methylcorrinoid
CC       protein + CoA + CO(2) + reduced ferredoxin = acetyl-CoA + corrinoid
CC       protein + H(2)O + oxidized ferredoxin.
DR   P27989, DCMB_MOOTH ;
//
ID   1.2.7.5
DE   Aldehyde ferredoxin oxidoreductase.
AN   AOR.
AN   Tungsten-containing aldehyde ferredoxin oxidoreductase.
CA   An aldehyde + H(2)O + 2 oxidized ferredoxin = an acid + 2 H(+) +
CA   2 reduced ferredoxin.
CF   Iron-sulfur; Tungsten-molybdopterin.
CC   -!- This is an oxygen-sensitive enzyme.
CC   -!- Catalyzes the oxidation of aldehydes (including crotonaldehyde,
CC       acetaldehyde, formaldehyde and glyceraldehyde) to their corresponding
CC       acids.
CC   -!- However, it does not oxidize glyceraldehyde 3-phosphate (see
CC       EC 1.2.7.6).
CC   -!- Can use ferredoxin or methyl viologen but not NAD(P)(+) as electron
CC       acceptor.
DR   Q9V035, AOR_PYRAB  ;  Q51739, AOR_PYRFU  ;  O58778, AOR_PYRHO  ;
DR   Q5JE15, AOR_PYRKO  ;  Q56303, FOR_THELI  ;
//
ID   1.2.7.6
DE   Glyceraldehyde-3-phosphate dehydrogenase (ferredoxin).
AN   GAPOR.
AN   Glyceraldehyde-3-phosphate Fd oxidoreductase.
AN   Glyceraldehyde-3-phosphate ferredoxin reductase.
CA   D-glyceraldehyde-3-phosphate + H(2)O + 2 oxidized ferredoxin = 3-phospho-
CA   D-glycerate + 2 H(+) + 2 reduced ferredoxin.
CF   Iron-sulfur; Tungsten-molybdopterin.
CC   -!- Thought to function in place of glyceraldehyde-3-phosphate
CC       dehydrogenase and possibly phosphoglycerate kinase in the novel
CC       Embden-Meyerhof-type glycolytic pathway found in Pyrococcus furiosus.
CC   -!- Specific for glyceraldehyde-3-phosphate.
//
ID   1.2.7.7
DE   3-methyl-2-oxobutanoate dehydrogenase (ferredoxin).
AN   2-ketoisovalerate ferredoxin reductase.
AN   2-oxoisovalerate ferredoxin reductase.
AN   3-methyl-2-oxobutanoate synthase (ferredoxin).
AN   Branched-chain ketoacid ferredoxin reductase.
AN   Branched-chain oxo acid ferredoxin reductase.
AN   Keto-valine-ferredoxin oxidoreductase.
AN   Ketoisovalerate ferredoxin reductase.
AN   Ketoisovalerate oxidoreductase.
AN   VOR.
CA   3-methyl-2-oxobutanoate + CoA + 2 oxidized ferredoxin =
CA   S-(2-methylpropanoyl)-CoA + CO(2) + 2 reduced ferredoxin + H(+).
CF   CoA; Iron-sulfur; Tungsten-molybdopterin.
CC   -!- One of four 2-oxoacid oxidoreductases that are differentiated by
CC       their abilities to oxidatively decarboxylate different 2-oxoacids and
CC       form their CoA derivatives (see also EC 1.2.7.1, EC 1.2.7.3 and
CC       EC 1.2.7.8).
CC   -!- Preferentially utilizes 2-oxo-acid derivatives of branched chain
CC       amino acids, e.g. 3-methyl-2-oxopentanoate, 4-methyl-2-oxo-
CC       pentanoate, 2-oxobutyrate and 3-methylthiopropanamine.
DR   Q9UYY9, PORC_PYRAB ;  P84819, PORC_PYREN ;  Q51799, PORC_PYRFU ;
DR   O58411, PORC_PYRHO ;  Q5JIK2, PORC_PYRKO ;  P84820, PORC_THELI ;
DR   O26801, VORA_METTH ;  Q9UYZ1, VORA_PYRAB ;  Q51801, VORA_PYRFU ;
DR   O58413, VORA_PYRHO ;  O26800, VORB_METTH ;  P80908, VORB_METTM ;
DR   Q9UYZ2, VORB_PYRAB ;  Q51802, VORB_PYRFU ;  O58414, VORB_PYRHO ;
DR   O26799, VORC_METTH ;  P80909, VORC_METTM ;  Q9UYZ0, VORD_PYRAB ;
DR   Q51800, VORD_PYRFU ;  O58412, VORD_PYRHO ;
//
ID   1.2.7.8
DE   Indolepyruvate ferredoxin oxidoreductase.
AN   3-(indol-3-yl)pyruvate synthase (ferredoxin).
AN   IOR.
CA   (Indol-3-yl)pyruvate + CoA + 2 oxidized ferredoxin = S-2-(indol-3-
CA   yl)acetyl-CoA + CO(2) + 2 reduced ferredoxin + H(+).
CF   Iron-sulfur; Thiamine diphosphate.
CC   -!- This enzyme, which is found in archaea, is one of four 2-oxoacid
CC       oxidoreductases that are differentiated by their abilities to
CC       oxidatively decarboxylate different 2-oxoacids and form their CoA
CC       derivatives (see also EC 1.2.7.1, EC 1.2.7.3 and EC 1.2.7.7).
CC   -!- Preferentially utilizes the transaminated forms of aromatic amino
CC       acids and can use phenylpyruvate and 4-hydroxyphenylpyruvate as
CC       substrates.
DR   O28783, IORA_ARCFU ;  O27880, IORA_METTH ;  P80910, IORA_METTM ;
DR   Q9UZ57, IORA_PYRAB ;  O58495, IORA_PYRHO ;  O07835, IORA_PYRKO ;
DR   O28249, IORB_ARCFU ;  O27881, IORB_METTH ;  P80911, IORB_METTM ;
DR   Q9UZ56, IORB_PYRAB ;  O58496, IORB_PYRHO ;  O07836, IORB_PYRKO ;
//
ID   1.2.7.9
DE   Transferred entry: 1.2.7.3.
//
ID   1.2.7.10
DE   Oxalate oxidoreductase.
CA   Oxalate + ferredoxin = 2 CO(2) + reduced ferredoxin.
CF   Iron-sulfur; Thiamine diphosphate.
//
ID   1.2.99.1
DE   Transferred entry: 1.17.99.4.
//
ID   1.2.99.2
DE   Carbon-monoxide dehydrogenase (acceptor).
AN   Anaerobic carbon monoxide dehydrogenase.
AN   Carbon monoxide oxygenase.
AN   Carbon-monoxide dehydrogenase.
CA   CO + H(2)O + A = CO(2) + AH(2).
CF   Iron-sulfur; Nickel.
CC   -!- It uses many electron acceptors, including ferredoxin, methyl
CC       viologen and benzyl viologen and flavins, but not pyridine
CC       nucleotides.
CC   -!- Forms part of a membrane-bound multienzyme complex with EC 1.12.99.6,
CC       which catalyzes the overall reaction: CO + H(2)O = CO(2) + H(2).
DR   O29165, ACDA1_ARCFU;  Q8TRZ4, ACDA1_METAC;  Q8TXF7, ACDA1_METKA;
DR   Q49161, ACDA1_METMA;  Q08368, ACDA1_METTE;  O30274, ACDA2_ARCFU;
DR   Q8TJC6, ACDA2_METAC;  Q49163, ACDA2_METMA;  Q9C4Z4, ACDA2_METTE;
DR   Q8THW2, ACDA3_METAC;  Q12XL7, ACDA_METBU ;  Q57617, ACDA_METJA ;
DR   P26692, ACDA_METSO ;  O27743, ACDA_METTH ;  P59934, COOS1_CARHZ;
DR   Q8TKW2, COOS1_METAC;  Q8Q0L5, COOS1_METMA;  Q9F8A8, COOS2_CARHZ;
DR   Q8TR73, COOS2_METAC;  Q8PUN1, COOS2_METMA;  O28429, COOS_ARCFU ;
DR   Q58138, COOS_METJA ;  Q8TXX3, COOS_METKA ;  P31896, COOS_RHORU ;
DR   P27989, DCMB_MOOTH ;  P19913, DCML_HYDPS ;  P19919, DCML_OLICO ;
DR   P19916, DCML_PSECH ;  P19914, DCMM_HYDPS ;  P19920, DCMM_OLICO ;
DR   P19917, DCMM_PSECH ;  P19915, DCMS_HYDPS ;  P19921, DCMS_OLICO ;
DR   P19918, DCMS_PSECH ;
//
ID   1.2.99.3
DE   Aldehyde dehydrogenase (pyrroloquinoline-quinone).
AN   Aldehyde dehydrogenase (acceptor).
CA   An aldehyde + acceptor + H(2)O = a carboxylate + reduced acceptor.
CF   Pyrroloquinoline quinone.
CC   -!- Wide specificity; acts on straight-chain aldehydes up to C(10),
CC       aromatic aldehydes, glyoxylate and glyceraldehyde.
DR   P80472, DHAB_AMYME ;  P80704, DHAB_COMTE ;  P80705, DHAG_COMTE ;
DR   P17201, DHAQ_ACEPO ;
//
ID   1.2.99.4
DE   Formaldehyde dismutase.
CA   2 formaldehyde + H(2)O = formate + methanol.
CC   -!- Formaldehyde and acetaldehyde can act as donors; formaldehyde,
CC       acetaldehyde and propanal can act as acceptors.
//
ID   1.2.99.5
DE   Formylmethanofuran dehydrogenase.
CA   Formylmethanofuran + H(2)O + acceptor = CO(2) + methanofuran + reduced
CA   acceptor.
CF   Molybdenum.
CC   -!- Methyl viologen can act as acceptor.
CC   -!- Also oxidizes N-furfurylformamide.
DR   Q48943, FMDC_METBF ;  O27002, FMDC_METTH ;  P61937, FMDC_METTM ;
DR   P61938, FMDC_METWO ;  P61154, FWDB_METJA ;  Q6LWL8, FWDB_METMP ;
DR   Q58571, FWDC_METJA ;  P0CW42, FWDC_METMI ;  P0CW43, FWDC_METMP ;
DR   O27600, FWDC_METTH ;  Q59579, FWDC_METTM ;  O74031, FWDC_METWO ;
DR   Q49611, FWDG_METKA ;
//
ID   1.2.99.6
DE   Carboxylate reductase.
CA   An aldehyde + acceptor + H(2)O = a carboxylate + reduced acceptor.
CF   Tungsten.
CC   -!- Methyl viologen can act as acceptor.
CC   -!- In the reverse direction, non-activated acids are reduced by reduced
CC       viologens to aldehydes, but not to the corresponding alcohols.
//
ID   1.2.99.7
DE   Aldehyde dehydrogenase (FAD-independent).
AN   Aldehyde oxidase.
AN   Aldehyde oxidoreductase.
AN   AORDd.
CA   An aldehyde + H(2)O + acceptor = a carboxylate + reduced acceptor.
CF   Iron-sulfur; Molybdopterin cytosine dinucleotide.
DR   Q46509, MOP_DESGI  ;
//
ID   1.3.1.1
DE   Dihydrouracil dehydrogenase (NAD(+)).
CA   5,6-dihydrouracil + NAD(+) = uracil + NADH.
DR   Q8X643, PREA_ECO57 ;  P25889, PREA_ECOLI ;  Q8ZNL7, PREA_SALTY ;
DR   Q8X645, PRET_ECO57 ;  P76440, PRET_ECOLI ;  Q8Z5A6, PRET_SALTI ;
DR   Q8ZNL8, PRET_SALTY ;
//
ID   1.3.1.2
DE   Dihydropyrimidine dehydrogenase (NADP(+)).
AN   Dihydrothymine dehydrogenase.
AN   Dihydrouracil dehydrogenase (NADP+).
CA   5,6-dihydrouracil + NADP(+) = uracil + NADPH.
CC   -!- Also acts on dihydrothymine.
DR   Q28007, DPYD_BOVIN ;  A8XKG6, DPYD_CAEBR ;  Q18164, DPYD_CAEEL ;
DR   Q6NYG8, DPYD_DANRE ;  Q55FT1, DPYD_DICDI ;  Q12882, DPYD_HUMAN ;
DR   Q8CHR6, DPYD_MOUSE ;  Q28943, DPYD_PIG   ;  Q5R895, DPYD_PONAB ;
DR   O89000, DPYD_RAT   ;
//
ID   1.3.1.3
DE   Delta(4)-3-oxosteroid 5-beta-reductase.
AN   3-oxo-Delta(4)-steroid 5-beta-reductase.
AN   5-beta-reductase.
AN   Androstenedione 5-beta-reductase.
AN   Cholestenone 5-beta-reductase.
AN   Cortisone 5-beta-reductase.
AN   Cortisone beta-reductase.
AN   Cortisone Delta(4)-5-beta-reductase.
AN   Delta(4)-3-ketosteroid 5-beta-reductase.
AN   Delta(4)-5-beta-reductase.
AN   Delta(4)-hydrogenase.
AN   Steroid 5-beta-reductase.
AN   Testosterone 5-beta-reductase.
CA   (1) 5-beta-cholestan-3-one + NADP(+) = cholest-4-en-3-one + NADPH.
CA   (2) 17,21-dihydroxy-5-beta-pregnane-3,11,20-trione + NADP(+) = cortisone
CA   + NADPH.
CC   -!- The enzyme from human efficiently catalyzes the reduction of
CC       progesterone, androstenedione, 17-alpha-hydroxyprogesterone and
CC       testosterone to 5-beta-reduced metabolites; it can also act on
CC       aldosterone, corticosterone and cortisol, but to a lesser extent.
CC   -!- The bile acid intermediates 7-alpha,12-alpha-dihydroxy-4-cholesten-3-
CC       one and 7-alpha-hydroxy-4-cholesten-3-one can also act as substrates.
PR   PROSITE; PDOC00061;
DR   P51857, AK1D1_HUMAN;  Q8VCX1, AK1D1_MOUSE;  Q9TV64, AK1D1_RABIT;
DR   P31210, AK1D1_RAT  ;
//
ID   1.3.1.4
DE   Cortisone alpha-reductase.
CA   4,5-alpha-dihydrocortisone + NADP(+) = cortisone + NADPH.
//
ID   1.3.1.5
DE   Cucurbitacin Delta(23)-reductase.
CA   23,24-dihydrocucurbitacin + NAD(P)(+) = cucurbitacin + NAD(P)H.
CF   Manganese.
CC   -!- Iron or zinc can replace manganese to some extent.
CC   -!- Cucurbitacin is a plant triterpenoid.
//
ID   1.3.1.6
DE   Fumarate reductase (NADH).
AN   NADH-dependent fumarate reductase.
CA   Succinate + NAD(+) = fumarate + NADH.
DR   O13755, FRDS_SCHPO ;  P32614, FRDS_YEAST ;
//
ID   1.3.1.7
DE   Meso-tartrate dehydrogenase.
CA   Meso-tartrate + NAD(+) = dihydroxyfumarate + NADH.
//
ID   1.3.1.8
DE   Acyl-CoA dehydrogenase (NADP(+)).
AN   2-enoyl-CoA reductase.
AN   Enoyl coenzyme A reductase.
CA   Acyl-CoA + NADP(+) = 2,3-dehydroacyl-CoA + NADPH.
CC   -!- The liver enzyme acts on enoyl-CoA derivatives of carbon chain length
CC       4 to 16, with optimum activity on 2-hexenoyl-CoA.
CC   -!- In Escherichia coli, cis-specific and trans-specific enzymes exist
CC       (cf. EC 1.3.1.37 and EC 1.3.1.38).
//
ID   1.3.1.9
DE   Enoyl-[acyl-carrier-protein] reductase (NADH).
AN   Enoyl-ACP reductase.
AN   NADH-enoyl acyl carrier protein reductase.
AN   NADH-specific enoyl-ACP reductase.
CA   Acyl-[acyl-carrier-protein] + NAD(+) = trans-2,3-dehydroacyl-[acyl-
CA   carrier-protein] + NADH.
CC   -!- Catalyzes the reduction of enoyl-acyl-[acyl-carrier-protein]
CC       derivatives of carbon chain length from 4 to 16.
DR   P58380, FABI1_RHIME;  P58381, FABI2_RHIME;  O67505, FABI_AQUAE ;
DR   Q81GI3, FABI_BACCR ;  P54616, FABI_BACSU ;  P80030, FABI_BRANA ;
DR   P57353, FABI_BUCAI ;  Q8K9Q6, FABI_BUCAP ;  Q89AM1, FABI_BUCBP ;
DR   P0AEK5, FABI_ECO57 ;  P0AEK4, FABI_ECOLI ;  Q820V5, FABI_ENTFA ;
DR   P44432, FABI_HAEIN ;  Q9ZMN7, FABI_HELPJ ;  O24990, FABI_HELPY ;
DR   Q9K151, FABI_NEIMB ;  Q05069, FABI_NOSS1 ;  Q9ZFE4, FABI_PSEAE ;
DR   Q9X450, FABI_RHIME ;  Q1RH28, FABI_RICBR ;  Q92IC6, FABI_RICCN ;
DR   Q4ULZ7, FABI_RICFE ;  Q9ZDG4, FABI_RICPR ;  Q68X10, FABI_RICTY ;
DR   P16657, FABI_SALTY ;  P0AEK6, FABI_SHIFL ;  P73016, FABI_SYNY3 ;
DR   P34731, FAS1_CANAL ;  Q9UUG0, FAS1_SCHPO ;  P34229, FAS1_YARLI ;
DR   P07149, FAS1_YEAST ;  O07400, INHA_MYCAV ;  P0A5Y7, INHA_MYCBO ;
DR   P42829, INHA_MYCS2 ;  P0A5Y6, INHA_MYCTU ;  Q92215, TOXC_COCCA ;
//
ID   1.3.1.10
DE   Enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific).
AN   Acyl-ACP dehydrogenase.
AN   Enoyl acyl-carrier-protein reductase.
AN   Enoyl-ACP reductase.
AN   NADPH 2-enoyl Co A reductase.
CA   Acyl-[acyl-carrier-protein] + NADP(+) = trans-2,3-dehydroacyl-[acyl-
CA   carrier-protein] + NADPH.
CC   -!- Catalyzes the reduction of enoyl-acyl-[acyl-carrier-protein]
CC       derivatives of carbon chain length from 4 to 16.
CC   -!- The Saccharomyces cerevisiae and Escherichia coli enzymes are
CC       B-specific with respect to NADP(+) (cf. EC 1.3.1.39).
DR   Q8WZM3, ETR1_CANTR ;  P38071, ETR1_YEAST ;  Q8WZM4, ETR2_CANTR ;
DR   Q2FZQ3, FABI_STAA8 ;  Q6GI75, FABI_STAAR ;  P71079, FABL_BACSU ;
DR   Q71SP7, FAS_BOVIN  ;  P12276, FAS_CHICK  ;  P49327, FAS_HUMAN  ;
DR   P19096, FAS_MOUSE  ;  P12785, FAS_RAT    ;
//
ID   1.3.1.11
DE   2-coumarate reductase.
AN   Melilotate dehydrogenase.
CA   3-(2-hydroxyphenyl)propanoate + NAD(+) = 2-coumarate + NADH.
//
ID   1.3.1.12
DE   Prephenate dehydrogenase.
AN   Chorismate mutase--prephenate dehydrogenase.
AN   Hydroxyphenylpyruvate synthase.
CA   Prephenate + NAD(+) = 4-hydroxyphenylpyruvate + CO(2) + NADH.
CC   -!- This enzyme in the enteric bacteria also possesses EC 5.4.99.5
CC       activity and converts chorismate into prephenate.
PR   PROSITE; PDOC51176;
DR   P20692, TYRA_BACSU ;  P07023, TYRA_ECOLI ;  Q02287, TYRA_ENTAG ;
DR   P43902, TYRA_HAEIN ;  Q9CET9, TYRA_LACLA ;  P43901, TYRA_LACLM ;
DR   Q8EH68, TYRA_SHEON ;  Q2FH71, TYRA_STAA3 ;  Q2FYS1, TYRA_STAA8 ;
DR   Q2YXV4, TYRA_STAAB ;  Q5HG54, TYRA_STAAC ;  Q99UB6, TYRA_STAAM ;
DR   Q7A5R7, TYRA_STAAN ;  Q6GH39, TYRA_STAAR ;  Q6G9J4, TYRA_STAAS ;
DR   Q8NWU6, TYRA_STAAW ;  Q5HPH6, TYRA_STAEQ ;  Q8CPB5, TYRA_STAES ;
DR   Q4L672, TYRA_STAHJ ;  Q49XG5, TYRA_STAS1 ;  Q04983, TYRC_ZYMMO ;
//
ID   1.3.1.13
DE   Prephenate dehydrogenase (NADP(+)).
CA   Prephenate + NADP(+) = 4-hydroxyphenylpyruvate + CO(2) + NADPH.
DR   O60078, TYR1_SCHPO ;  P20049, TYR1_YEAST ;
//
ID   1.3.1.14
DE   Dihydroorotate dehydrogenase (NAD(+)).
AN   DHOD.
AN   DHODase.
AN   DHOdehase.
AN   Dihydroorotate oxidase.
AN   Orotate reductase (NADH(2)).
AN   Orotate reductase (NADH).
CA   (S)-dihydroorotate + NAD(+) = orotate + NADH.
CF   FAD; FMN; Iron-sulfur.
CC   -!- The enzyme consists of two subunits, an FMN binding catalytic subunit
CC       and a FAD and iron-sulfur binding electron transfer subunit.
CC   -!- The reaction, which takes place in the cytosol, is the only redox
CC       reaction in the de-novo biosynthesis of pyrimidine nucleotides.
CC   -!- Other class 1 dihydroorotate dehydrogenases use either fumarate
CC       (EC 1.3.98.1) or NADP(+) (EC 1.3.1.15) as electron acceptor.
CC   -!- The membrane bound class 2 dihydroorotate dehydrogenase (EC 1.3.5.2)
CC       uses quinone as electron acceptor.
DR   A6TVS0, PYRDB_ALKMQ;  A8MIU4, PYRDB_ALKOO;  B9MS26, PYRDB_ANATD;
DR   B7GFA1, PYRDB_ANOFW;  O29513, PYRDB_ARCFU;  B6YRL9, PYRDB_AZOPC;
DR   A7Z4H4, PYRDB_BACA2;  C3P654, PYRDB_BACAA;  C3L742, PYRDB_BACAC;
DR   A0RHQ6, PYRDB_BACAH;  Q81WF4, PYRDB_BACAN;  B7JJX1, PYRDB_BACC0;
DR   Q732I5, PYRDB_BACC1;  B7IUP4, PYRDB_BACC2;  C1EPP8, PYRDB_BACC3;
DR   B7H6M0, PYRDB_BACC4;  B7HLL8, PYRDB_BACC7;  P46539, PYRDB_BACCL;
DR   A7GRK9, PYRDB_BACCN;  B9IVW1, PYRDB_BACCQ;  Q819S5, PYRDB_BACCR;
DR   Q636E2, PYRDB_BACCZ;  Q5LCI2, PYRDB_BACFN;  Q64TN0, PYRDB_BACFR;
DR   Q9K9W1, PYRDB_BACHD;  Q6HET0, PYRDB_BACHK;  A8FD19, PYRDB_BACP2;
DR   Q5WFJ4, PYRDB_BACSK;  P25996, PYRDB_BACSU;  Q8A9C3, PYRDB_BACTN;
DR   A6L5H1, PYRDB_BACV8;  A9VTC4, PYRDB_BACWK;  C0QYH6, PYRDB_BRAHW;
DR   A4XKT6, PYRDB_CALS8;  Q3AC05, PYRDB_CARHZ;  Q18CS6, PYRDB_CLOD6;
DR   A9KKR5, PYRDB_CLOPH;  C6BW12, PYRDB_DESAD;  B1I4M6, PYRDB_DESAP;
DR   C4XPD6, PYRDB_DESMR;  A4J560, PYRDB_DESRM;  P0DH74, PYRDB_ENTFA;
DR   F2MMN9, PYRDB_ENTFO;  B1YIR7, PYRDB_EXIS2;  Q8RG85, PYRDB_FUSNN;
DR   B5EFU4, PYRDB_GEOBB;  Q5L0U1, PYRDB_GEOKA;  B3E4T4, PYRDB_GEOLS;
DR   Q39UK4, PYRDB_GEOMG;  B9M211, PYRDB_GEOSF;  Q74CB9, PYRDB_GEOSL;
DR   C6E6N2, PYRDB_GEOSM;  C5D8Q2, PYRDB_GEOSW;  A4IM35, PYRDB_GEOTN;
DR   A5G3H0, PYRDB_GEOUR;  B0TGQ8, PYRDB_HELMI;  Q9CFW8, PYRDB_LACLA;
DR   P54322, PYRDB_LACLM;  Q38X22, PYRDB_LACSS;  Q92AH5, PYRDB_LISIN;
DR   C1KWD2, PYRDB_LISMC;  Q71YI3, PYRDB_LISMF;  B8DDR9, PYRDB_LISMH;
DR   Q8Y667, PYRDB_LISMO;  A0AJT8, PYRDB_LISW6;  Q8TT55, PYRDB_METAC;
DR   Q58070, PYRDB_METJA;  Q8TXU6, PYRDB_METKA;  Q8PW56, PYRDB_METMA;
DR   O27281, PYRDB_METTH;  Q8EUY2, PYRDB_MYCPE;  B2A2U4, PYRDB_NATTJ;
DR   Q8CWG1, PYRDB_OCEIH;  A6LB11, PYRDB_PARD8;  A1ASB3, PYRDB_PELPD;
DR   A9BJH4, PYRDB_PETMO;  Q7MVJ6, PYRDB_PORGI;  Q6A912, PYRDB_PROAC;
DR   Q9V0Y6, PYRDB_PYRAB;  Q8U0P6, PYRDB_PYRFU;  O59185, PYRDB_PYRHO;
DR   Q5JHR7, PYRDB_PYRKO;  B9DPN4, PYRDB_STACT;  Q97R65, PYRDB_STRPN;
DR   Q8DQ37, PYRDB_STRR6;  O08358, PYRDB_SULAC;  Q9UX04, PYRDB_SULSO;
DR   Q0AXG6, PYRDB_SYNWW;  Q9HL35, PYRDB_THEAC;  Q9WYG8, PYRDB_THEMA;
DR   A5IK84, PYRDB_THEP1;  B0KA32, PYRDB_THEP3;  B0K2E5, PYRDB_THEPX;
DR   Q8R9R7, PYRDB_THETN;  Q979G6, PYRDB_THEVO;  B5YJH1, PYRDB_THEYD;
DR   Q0W8E1, PYRDB_UNCMA;  B1GYY3, PYRDB_UNCTG;
//
ID   1.3.1.15
DE   Dihydroorotate dehydrogenase (NADP(+)).
CA   (S)-dihydroorotate + NADP(+) = orotate + NADPH.
CF   FAD; FMN.
CC   -!- Other class 1 dihydroorotate dehydrogenases use either fumarate
CC       (EC 1.3.98.1) or NAD(+) (EC 1.3.1.14) as electron acceptor.
CC   -!- The membrane bound class 2 dihydroorotate dehydrogenase (EC 1.3.5.2)
CC       uses quinone as electron acceptor.
//
ID   1.3.1.16
DE   Beta-nitroacrylate reductase.
CA   3-nitropropanoate + NADP(+) = 3-nitroacrylate + NADPH.
//
ID   1.3.1.17
DE   3-methyleneoxindole reductase.
CA   3-methyl-1,3-dihydroindol-2-one + NADP(+) = 3-methylene-1,3-dihydro-
CA   2H-indol-2-one + NADPH.
//
ID   1.3.1.18
DE   Kynurenate-7,8-dihydrodiol dehydrogenase.
CA   7,8-dihydro-7,8-dihydroxykynurenate + NAD(+) = 7,8-dihydroxykynurenate +
CA   NADH.
//
ID   1.3.1.19
DE   Cis-1,2-dihydrobenzene-1,2-diol dehydrogenase.
AN   Cis-benzene glycol dehydrogenase.
CA   Cis-1,2-dihydrobenzene-1,2-diol + NAD(+) = catechol + NADH.
PR   PROSITE; PDOC00060;
DR   P08088, BNZE_PSEPU ;
//
ID   1.3.1.20
DE   Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase.
CA   Trans-1,2-dihydrobenzene-1,2-diol + NADP(+) = catechol + NADPH.
PR   PROSITE; PDOC00061;
DR   Q04828, AK1C1_HUMAN;  P52895, AK1C2_HUMAN;  P42330, AK1C3_HUMAN;
DR   Q5R7C9, AK1C3_PONAB;  Q148L6, DHDH_BOVIN ;  Q9TV68, DHDH_CANFA ;
DR   Q642M9, DHDH_DANRE ;  Q9UQ10, DHDH_HUMAN ;  Q9TQS6, DHDH_MACFA ;
DR   Q7JK39, DHDH_MACFU ;  Q9DBB8, DHDH_MOUSE ;  Q9TV69, DHDH_PIG   ;
DR   Q5R5J5, DHDH_PONAB ;  Q9TV70, DHDH_RABIT ;  Q6DKE0, DHDH_XENLA ;
DR   Q6DF30, DHDH_XENTR ;
//
ID   1.3.1.21
DE   7-dehydrocholesterol reductase.
AN   7-DHC reductase.
AN   Sterol Delta(7)-reductase.
CA   Cholesterol + NADP(+) = cholesta-5,7-dien-3-beta-ol + NADPH.
DR   Q5E9J5, DHCR7_BOVIN;  Q7SXF1, DHCR7_DANRE;  Q9UBM7, DHCR7_HUMAN;
DR   Q5UQI4, DHCR7_MIMIV;  O88455, DHCR7_MOUSE;  Q9Z2Z8, DHCR7_RAT  ;
DR   Q7ZXH1, DHCR7_XENLA;  Q6P4M0, DHCR7_XENTR;  Q9LDU6, ST7R_ARATH ;
//
ID   1.3.1.22
DE   Cholestenone 5-alpha-reductase.
CA   5-alpha-cholestan-3-one + NADP(+) = cholest-4-en-3-one + NADPH.
//
ID   1.3.1.23
DE   Deleted entry.
//
ID   1.3.1.24
DE   Biliverdin reductase.
CA   Bilirubin + NAD(P)(+) = biliverdin + NAD(P)H.
DR   P53004, BIEA_HUMAN ;  Q9CY64, BIEA_MOUSE ;  P46844, BIEA_RAT   ;
DR   P52556, BLVRB_BOVIN;  P30043, BLVRB_HUMAN;  Q923D2, BLVRB_MOUSE;
//
ID   1.3.1.25
DE   1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase.
AN   2-hydro-1,2-dihydroxybenzoate dehydrogenase.
AN   3,5-cyclohexadiene-1,2-diol-1-carboxylate dehydrogenase.
AN   3,5-cyclohexadiene-1,2-diol-1-carboxylic acid dehydrogenase.
AN   Cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase.
AN   Cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD(+) oxidoreductase.
AN   DHB dehydrogenase.
AN   DHBDH.
AN   Dihydrodihydroxybenzoate dehydrogenase.
CA   (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+) =
CA   catechol + CO(2) + NADH.
PR   PROSITE; PDOC00060;
DR   P07772, BEND_ACIAD ;  P23102, XYLL_PSEPU ;
//
ID   1.3.1.26
DE   Dihydrodipicolinate reductase.
CA   (S)-2,3,4,5-tetrahydrodipicolinate + NAD(P)(+) = (S)-2,3-
CA   dihydrodipicolinate + NAD(P)H.
PR   PROSITE; PDOC01000;
DR   O80574, DAPB1_ARATH;  Q7TXX0, DAPB1_MYCBO;  Q67W29, DAPB1_ORYSJ;
DR   P58210, DAPB1_RHILO;  P58326, DAPB1_RHIME;  Q8LB01, DAPB2_ARATH;
DR   P46829, DAPB2_MYCBO;  Q10P67, DAPB2_ORYSJ;  P58211, DAPB2_RHILO;
DR   O69783, DAPB2_RHIME;  Q9FJ82, DAPB3_ARATH;  B0CE31, DAPB_ACAM1 ;
DR   Q6F6R2, DAPB_ACIAD ;  B7GV10, DAPB_ACIB3 ;  B7I2B0, DAPB_ACIB5 ;
DR   B2I2G4, DAPB_ACIBC ;  B0VPZ8, DAPB_ACIBS ;  A3MA87, DAPB_ACIBT ;
DR   B0VA26, DAPB_ACIBY ;  A5FXD9, DAPB_ACICJ ;  A3N048, DAPB_ACTP2 ;
DR   B3H1A7, DAPB_ACTP7 ;  B0BNW4, DAPB_ACTPJ ;  A6VPE4, DAPB_ACTSZ ;
DR   A4SLF8, DAPB_AERS4 ;  B9J6R4, DAPB_AGRRK ;  Q8UIV8, DAPB_AGRT5 ;
DR   B9JYQ3, DAPB_AGRVS ;  B2UMF1, DAPB_AKKM8 ;  Q0A7E5, DAPB_ALHEH ;
DR   B6ENC8, DAPB_ALISL ;  A6TT16, DAPB_ALKMQ ;  A8MF41, DAPB_ALKOO ;
DR   B8JAN4, DAPB_ANAD2 ;  Q2IGX0, DAPB_ANADE ;  A7H774, DAPB_ANADF ;
DR   Q5PA93, DAPB_ANAMM ;  B4UHF2, DAPB_ANASK ;  Q3MFY8, DAPB_ANAVT ;
DR   O67061, DAPB_AQUAE ;  A8EWI3, DAPB_ARCB4 ;  O29353, DAPB_ARCFU ;
DR   Q5P1G6, DAPB_AROAE ;  C1DFM1, DAPB_AZOVD ;  A7Z600, DAPB_BACA2 ;
DR   C3P5Q2, DAPB_BACAA ;  C3L8Q7, DAPB_BACAC ;  A0RBY6, DAPB_BACAH ;
DR   Q81SU0, DAPB_BACAN ;  B7JH17, DAPB_BACC0 ;  Q73AW1, DAPB_BACC1 ;
DR   B7IPB0, DAPB_BACC2 ;  C1EN29, DAPB_BACC3 ;  B7HHT6, DAPB_BACC4 ;
DR   B7HL46, DAPB_BACC7 ;  A7GN70, DAPB_BACCN ;  B9IVQ5, DAPB_BACCQ ;
DR   Q81FP4, DAPB_BACCR ;  Q63DK0, DAPB_BACCZ ;  Q9KC93, DAPB_BACHD ;
DR   Q6HL23, DAPB_BACHK ;  Q65I50, DAPB_BACLD ;  A8FEI3, DAPB_BACP2 ;
DR   Q5WGQ4, DAPB_BACSK ;  P42976, DAPB_BACSU ;  A9VME3, DAPB_BACWK ;
DR   A1UTM3, DAPB_BARBK ;  Q6G2G3, DAPB_BARHE ;  Q6FZ13, DAPB_BARQU ;
DR   A9IXE5, DAPB_BART1 ;  Q6MRM8, DAPB_BDEBA ;  B2IBR8, DAPB_BEII9 ;
DR   C5BWQ6, DAPB_BEUC1 ;  B8DWI3, DAPB_BIFA0 ;  Q8G526, DAPB_BIFLO ;
DR   B7GUF6, DAPB_BIFLS ;  Q7VQK8, DAPB_BLOFL ;  Q493S0, DAPB_BLOPB ;
DR   Q7WGH5, DAPB_BORBR ;  Q7W510, DAPB_BORPA ;  Q9X6Y9, DAPB_BORPE ;
DR   C0R175, DAPB_BRAHW ;  Q89WK2, DAPB_BRAJA ;  A5E8K0, DAPB_BRASB ;
DR   A4YJP9, DAPB_BRASO ;  Q2YJN7, DAPB_BRUA2 ;  Q576R4, DAPB_BRUAB ;
DR   Q8YDC8, DAPB_BRUME ;  Q8FV07, DAPB_BRUSU ;  B8D8U7, DAPB_BUCA5 ;
DR   P57246, DAPB_BUCAI ;  Q8K9Z5, DAPB_BUCAP ;  B8D751, DAPB_BUCAT ;
DR   P59474, DAPB_BUCBP ;  Q057Y0, DAPB_BUCCC ;  B1YT08, DAPB_BURA4 ;
DR   Q1BZ73, DAPB_BURCA ;  B1JVG6, DAPB_BURCC ;  A0K4H7, DAPB_BURCH ;
DR   B4EEW4, DAPB_BURCJ ;  Q0BIB8, DAPB_BURCM ;  A9AHB2, DAPB_BURM1 ;
DR   A3MPI2, DAPB_BURM7 ;  A2S5J7, DAPB_BURM9 ;  Q62H17, DAPB_BURMA ;
DR   A1V0H0, DAPB_BURMS ;  A3NZB9, DAPB_BURP0 ;  Q3JNM7, DAPB_BURP1 ;
DR   A3NDK8, DAPB_BURP6 ;  B2JGX9, DAPB_BURP8 ;  Q63QT3, DAPB_BURPS ;
DR   Q39JM8, DAPB_BURS3 ;  Q2SZ94, DAPB_BURTA ;  A4JBH8, DAPB_BURVG ;
DR   A7ZB70, DAPB_CAMC1 ;  A7GWC2, DAPB_CAMC5 ;  A0RMR7, DAPB_CAMFF ;
DR   A7I316, DAPB_CAMHC ;  A8FJZ8, DAPB_CAMJ8 ;  A7H1R4, DAPB_CAMJD ;
DR   Q9PIT2, DAPB_CAMJE ;  A1VXS5, DAPB_CAMJJ ;  Q5HWX1, DAPB_CAMJR ;
DR   B9KDT6, DAPB_CAMLR ;  Q3ACY8, DAPB_CARHZ ;  Q9A2L1, DAPB_CAUCR ;
DR   Q5L5G4, DAPB_CHLAB ;  Q3APL9, DAPB_CHLCH ;  Q822G7, DAPB_CHLCV ;
DR   Q255G3, DAPB_CHLFF ;  B3EG74, DAPB_CHLL2 ;  Q9PK30, DAPB_CHLMU ;
DR   B3QKY9, DAPB_CHLP8 ;  B3EN04, DAPB_CHLPB ;  A1BI80, DAPB_CHLPD ;
DR   Q9Z6L2, DAPB_CHLPN ;  B3QYM8, DAPB_CHLT3 ;  Q3KLZ2, DAPB_CHLTA ;
DR   Q8KBD8, DAPB_CHLTE ;  O84369, DAPB_CHLTR ;  Q1QSX7, DAPB_CHRSD ;
DR   Q7NX34, DAPB_CHRVO ;  A8ALS4, DAPB_CITK8 ;  A5CSN2, DAPB_CLAM3 ;
DR   B0RGX5, DAPB_CLAMS ;  Q97GI8, DAPB_CLOAB ;  B2V5A9, DAPB_CLOBA ;
DR   B2TS69, DAPB_CLOBB ;  A0PZM2, DAPB_CLONN ;  Q0TP54, DAPB_CLOP1 ;
DR   Q8XJ55, DAPB_CLOPE ;  Q0SRS4, DAPB_CLOPS ;  Q891S2, DAPB_CLOTE ;
DR   Q47YI6, DAPB_COLP3 ;  C3PH06, DAPB_CORA7 ;  Q6NGP2, DAPB_CORDI ;
DR   Q8RQN0, DAPB_COREF ;  A4QEY0, DAPB_CORGB ;  P40110, DAPB_CORGL ;
DR   Q4JV62, DAPB_CORJK ;  B1VDC2, DAPB_CORU7 ;  B6J4U6, DAPB_COXB1 ;
DR   B6J2F3, DAPB_COXB2 ;  A9KC25, DAPB_COXBN ;  A9NA71, DAPB_COXBR ;
DR   P24703, DAPB_COXBU ;  Q0K705, DAPB_CUPNH ;  Q46XD7, DAPB_CUPPJ ;
DR   B3R6R4, DAPB_CUPTR ;  B8HRK9, DAPB_CYAP4 ;  B7KBV6, DAPB_CYAP7 ;
DR   B7JW41, DAPB_CYAP8 ;  Q47HI9, DAPB_DECAR ;  Q3Z7V5, DAPB_DEHE1 ;
DR   A5FQT3, DAPB_DEHSB ;  Q3ZXV5, DAPB_DEHSC ;  C6BTW9, DAPB_DESAD ;
DR   B8J0P9, DAPB_DESDA ;  Q30ZK7, DAPB_DESDG ;  B8FQZ3, DAPB_DESHD ;
DR   Q24UK0, DAPB_DESHY ;  Q6AR64, DAPB_DESPS ;  Q72BM6, DAPB_DESVH ;
DR   B8DJT5, DAPB_DESVM ;  A1VDM6, DAPB_DESVV ;  B5YEB2, DAPB_DICT6 ;
DR   B8E2S7, DAPB_DICTD ;  A8LL24, DAPB_DINSH ;  A7ZHC0, DAPB_ECO24 ;
DR   B7UI76, DAPB_ECO27 ;  B7MAF2, DAPB_ECO45 ;  B7L4F3, DAPB_ECO55 ;
DR   P58209, DAPB_ECO57 ;  B5YYC3, DAPB_ECO5E ;  B7NHD5, DAPB_ECO7I ;
DR   B7MNN7, DAPB_ECO81 ;  B7M0C7, DAPB_ECO8A ;  C4ZPV7, DAPB_ECOBW ;
DR   B1XBF6, DAPB_ECODH ;  A7ZVX9, DAPB_ECOHS ;  A1A780, DAPB_ECOK1 ;
DR   Q0TLW0, DAPB_ECOL5 ;  Q8FLB4, DAPB_ECOL6 ;  B1IRE5, DAPB_ECOLC ;
DR   P04036, DAPB_ECOLI ;  B7N7Q5, DAPB_ECOLU ;  B6HYX9, DAPB_ECOSE ;
DR   B1LFW1, DAPB_ECOSM ;  Q1RGH0, DAPB_ECOUT ;  C5B7N2, DAPB_EDWI9 ;
DR   Q3YRP2, DAPB_EHRCJ ;  Q2GH22, DAPB_EHRCR ;  Q5FFT0, DAPB_EHRRG ;
DR   Q5HAV4, DAPB_EHRRW ;  A4W6E7, DAPB_ENT38 ;  Q834S6, DAPB_ENTFA ;
DR   A7MI96, DAPB_ENTS8 ;  Q6D0C7, DAPB_ERWCT ;  B2VH06, DAPB_ERWT9 ;
DR   B7LWM1, DAPB_ESCF3 ;  B1YJ40, DAPB_EXIS2 ;  C4L2D3, DAPB_EXISA ;
DR   B5EGX3, DAPB_GEOBB ;  Q5KXW6, DAPB_GEOKA ;  B3E935, DAPB_GEOLS ;
DR   Q39Z66, DAPB_GEOMG ;  B9M381, DAPB_GEOSF ;  Q74GT5, DAPB_GEOSL ;
DR   C6E9Q8, DAPB_GEOSM ;  A4IQ67, DAPB_GEOTN ;  A5GD90, DAPB_GEOUR ;
DR   Q7NLC0, DAPB_GLOVI ;  A9HE99, DAPB_GLUDA ;  Q5FSK8, DAPB_GLUOX ;
DR   Q0BPE6, DAPB_GRABC ;  A0LZI4, DAPB_GRAFK ;  Q7VLM6, DAPB_HAEDU ;
DR   Q4QKM7, DAPB_HAEI8 ;  A5UCB3, DAPB_HAEIE ;  A5UF10, DAPB_HAEIG ;
DR   P45153, DAPB_HAEIN ;  B8F8Q1, DAPB_HAEPS ;  Q0I3N1, DAPB_HAES1 ;
DR   B0UU27, DAPB_HAES2 ;  Q2SMM6, DAPB_HAHCH ;  A1WX29, DAPB_HALHL ;
DR   Q5V5D5, DAPB_HALMA ;  Q17XF1, DAPB_HELAH ;  Q7VIW7, DAPB_HELHP ;
DR   B6JL92, DAPB_HELP2 ;  B5Z6N2, DAPB_HELPG ;  Q1CU21, DAPB_HELPH ;
DR   Q9ZLW6, DAPB_HELPJ ;  B2UTX8, DAPB_HELPS ;  P94844, DAPB_HELPY ;
DR   A4G8E2, DAPB_HERAR ;  Q5QXL5, DAPB_IDILO ;  A6T235, DAPB_JANMA ;
DR   B5Y210, DAPB_KLEP3 ;  A6T4H8, DAPB_KLEP7 ;  P45415, DAPB_KLEPN ;
DR   Q5FKQ8, DAPB_LACAC ;  B2GC12, DAPB_LACF3 ;  A8YUT4, DAPB_LACH4 ;
DR   Q9CFC0, DAPB_LACLA ;  A2RJS9, DAPB_LACLM ;  Q02Y20, DAPB_LACLS ;
DR   Q88W01, DAPB_LACPL ;  Q1WU20, DAPB_LACS1 ;  C1D7H9, DAPB_LARHH ;
DR   Q1MRS7, DAPB_LAWIP ;  Q5X8U7, DAPB_LEGPA ;  A5I9V1, DAPB_LEGPC ;
DR   Q5ZZ80, DAPB_LEGPH ;  Q5X090, DAPB_LEGPL ;  Q04U79, DAPB_LEPBJ ;
DR   Q053P2, DAPB_LEPBL ;  Q72U21, DAPB_LEPIC ;  Q8F133, DAPB_LEPIN ;
DR   Q92AA1, DAPB_LISIN ;  C1KWK7, DAPB_LISMC ;  Q71YA8, DAPB_LISMF ;
DR   B8DC19, DAPB_LISMH ;  Q8Y5Z6, DAPB_LISMO ;  A0AK12, DAPB_LISW6 ;
DR   B1HTF0, DAPB_LYSSC ;  A0L4Z4, DAPB_MAGSM ;  Q65TY2, DAPB_MANSM ;
DR   Q9S3W8, DAPB_MASLA ;  Q11CB4, DAPB_MESSB ;  A6UUT2, DAPB_META3 ;
DR   Q8THP0, DAPB_METAC ;  A7I854, DAPB_METB6 ;  Q46DC3, DAPB_METBF ;
DR   Q12ZG1, DAPB_METBU ;  Q607A7, DAPB_METCA ;  Q2FNQ9, DAPB_METHJ ;
DR   Q57865, DAPB_METJA ;  Q8TVG7, DAPB_METKA ;  A2SQU7, DAPB_METLZ ;
DR   A4FXV6, DAPB_METM5 ;  A9AB21, DAPB_METM6 ;  A6VFL4, DAPB_METM7 ;
DR   Q8PXL6, DAPB_METMA ;  A3CVI6, DAPB_METMJ ;  Q6LYR5, DAPB_METMP ;
DR   A5ULF7, DAPB_METS3 ;  B8EIQ3, DAPB_METSB ;  Q2NHW0, DAPB_METST ;
DR   O26891, DAPB_METTH ;  A6UNQ4, DAPB_METVS ;  Q2RJL2, DAPB_MOOTA ;
DR   A1KMB5, DAPB_MYCBP ;  C1AFN6, DAPB_MYCBT ;  A4TCI6, DAPB_MYCGI ;
DR   B2HKW6, DAPB_MYCMM ;  Q73VY3, DAPB_MYCPA ;  A0QVR3, DAPB_MYCS2 ;
DR   A3PYA0, DAPB_MYCSJ ;  A1UEU3, DAPB_MYCSK ;  Q1BA69, DAPB_MYCSS ;
DR   A5U6C6, DAPB_MYCTA ;  P72024, DAPB_MYCTU ;  A0PQF8, DAPB_MYCUA ;
DR   A1T7N8, DAPB_MYCVP ;  Q1CZV9, DAPB_MYXXD ;  Q3ISP9, DAPB_NATPD ;
DR   Q5F5Y7, DAPB_NEIG1 ;  B4RR35, DAPB_NEIG2 ;  A9M3H7, DAPB_NEIM0 ;
DR   Q9JX48, DAPB_NEIMA ;  Q9K1F1, DAPB_NEIMB ;  A1KRN3, DAPB_NEIMF ;
DR   Q0AER1, DAPB_NITEC ;  Q82WP9, DAPB_NITEU ;  Q2YBT6, DAPB_NITMU ;
DR   Q3J7E0, DAPB_NITOC ;  A6Q596, DAPB_NITSB ;  Q3SW72, DAPB_NITWN ;
DR   Q5YSW2, DAPB_NOCFA ;  B2J0A9, DAPB_NOSP7 ;  Q8YU19, DAPB_NOSS1 ;
DR   Q8EQD3, DAPB_OCEIH ;  B6JCI8, DAPB_OLICO ;  A7HZ36, DAPB_PARL1 ;
DR   P57867, DAPB_PASMU ;  C6DF00, DAPB_PECCP ;  Q3A1U6, DAPB_PELCD ;
DR   Q3B619, DAPB_PELLD ;  B4SEU9, DAPB_PELPB ;  A1ATI7, DAPB_PELPD ;
DR   Q4FNQ1, DAPB_PELUB ;  Q7N8W3, DAPB_PHOLL ;  Q6LUK7, DAPB_PHOPR ;
DR   B1XT71, DAPB_POLNS ;  Q6A7P7, DAPB_PROAC ;  Q7VC38, DAPB_PROMA ;
DR   B4F2T9, DAPB_PROMH ;  Q7V7D4, DAPB_PROMM ;  Q7V1N1, DAPB_PROMP ;
DR   Q46KV7, DAPB_PROMT ;  A4SD53, DAPB_PROVI ;  Q48E64, DAPB_PSE14 ;
DR   Q15TQ4, DAPB_PSEA6 ;  A6VCL6, DAPB_PSEA7 ;  B7V1H1, DAPB_PSEA8 ;
DR   Q02FR3, DAPB_PSEAB ;  P38103, DAPB_PSEAE ;  Q1IF57, DAPB_PSEE4 ;
DR   Q4KIG9, DAPB_PSEF5 ;  Q84CP9, DAPB_PSEFS ;  Q3IKQ7, DAPB_PSEHT ;
DR   A4XYF4, DAPB_PSEMY ;  A5W9A1, DAPB_PSEP1 ;  Q3KI98, DAPB_PSEPF ;
DR   B0KIS3, DAPB_PSEPG ;  Q88DU4, DAPB_PSEPK ;  B1J256, DAPB_PSEPW ;
DR   Q87WP2, DAPB_PSESM ;  Q52419, DAPB_PSESZ ;  Q4ZNP9, DAPB_PSEU2 ;
DR   A4VPQ3, DAPB_PSEU5 ;  Q4FVQ6, DAPB_PSYA2 ;  Q1LJ29, DAPB_RALME ;
DR   B2UCA2, DAPB_RALPJ ;  Q8XVT2, DAPB_RALSO ;  C3MBY7, DAPB_RHISN ;
DR   Q7UJD7, DAPB_RHOBA ;  Q2J314, DAPB_RHOP2 ;  Q07UT2, DAPB_RHOP5 ;
DR   Q6NCX8, DAPB_RHOPA ;  Q21CH6, DAPB_RHOPB ;  Q13E66, DAPB_RHOPS ;
DR   B3Q978, DAPB_RHOPT ;  A3PNF3, DAPB_RHOS1 ;  Q3IYU4, DAPB_RHOS4 ;
DR   A4WWP7, DAPB_RHOS5 ;  B9KP40, DAPB_RHOSK ;  C3PMI6, DAPB_RICAE ;
DR   A8GMB6, DAPB_RICAH ;  A8GV42, DAPB_RICB8 ;  Q1RHE5, DAPB_RICBR ;
DR   A8EXL6, DAPB_RICCK ;  Q92J79, DAPB_RICCN ;  Q4UKE7, DAPB_RICFE ;
DR   Q9ZE14, DAPB_RICPR ;  C4K0R8, DAPB_RICPU ;  A8GQX3, DAPB_RICRS ;
DR   Q68XM0, DAPB_RICTY ;  Q16CE5, DAPB_ROSDO ;  Q1AZV2, DAPB_RUBXD ;
DR   Q21H39, DAPB_SACD2 ;  B5F744, DAPB_SALA4 ;  A9MR41, DAPB_SALAR ;
DR   Q57TJ7, DAPB_SALCH ;  B5FHF8, DAPB_SALDC ;  B5R1Q4, DAPB_SALEP ;
DR   B5RG99, DAPB_SALG2 ;  B4TIG4, DAPB_SALHS ;  B4T6J1, DAPB_SALNS ;
DR   Q5PIL9, DAPB_SALPA ;  A9MYI6, DAPB_SALPB ;  C0Q4K5, DAPB_SALPC ;
DR   B5BL41, DAPB_SALPK ;  B4TWQ6, DAPB_SALSV ;  Q8Z9L9, DAPB_SALTI ;
DR   Q8ZRX8, DAPB_SALTY ;  A8G9M8, DAPB_SERP5 ;  A1S8K1, DAPB_SHEAM ;
DR   B8E4S9, DAPB_SHEB2 ;  A3D7S3, DAPB_SHEB5 ;  A6WRU0, DAPB_SHEB8 ;
DR   A9L0Q8, DAPB_SHEB9 ;  Q12QJ4, DAPB_SHEDO ;  Q086I8, DAPB_SHEFN ;
DR   B0TQB8, DAPB_SHEHH ;  A3QGV8, DAPB_SHELP ;  Q8EHS7, DAPB_SHEON ;
DR   A8H756, DAPB_SHEPA ;  A4Y9M3, DAPB_SHEPC ;  B8CKF7, DAPB_SHEPW ;
DR   A0KTT2, DAPB_SHESA ;  A8FYT6, DAPB_SHESH ;  Q0HLM3, DAPB_SHESM ;
DR   Q0HY04, DAPB_SHESR ;  A1RGQ6, DAPB_SHESW ;  B1KRS8, DAPB_SHEWM ;
DR   B2U250, DAPB_SHIB3 ;  Q326J2, DAPB_SHIBS ;  Q32K66, DAPB_SHIDS ;
DR   Q83SQ9, DAPB_SHIFL ;  Q3Z5X9, DAPB_SHISS ;  Q5LLT7, DAPB_SILPO ;
DR   Q1GKJ6, DAPB_SILST ;  A6UEW2, DAPB_SINMW ;  Q2NVY2, DAPB_SODGM ;
DR   A7X273, DAPB_STAA1 ;  A6U1L7, DAPB_STAA2 ;  Q2FH42, DAPB_STAA3 ;
DR   Q9EZ11, DAPB_STAA8 ;  A5ISS8, DAPB_STAA9 ;  Q2YXX3, DAPB_STAAB ;
DR   Q5HG24, DAPB_STAAC ;  A6QGU7, DAPB_STAAE ;  P63893, DAPB_STAAM ;
DR   P63894, DAPB_STAAN ;  Q6GH12, DAPB_STAAR ;  Q6G9G5, DAPB_STAAS ;
DR   A8Z3X4, DAPB_STAAT ;  Q8NWS4, DAPB_STAAW ;  B9DP24, DAPB_STACT ;
DR   Q5HPE6, DAPB_STAEQ ;  Q8CP95, DAPB_STAES ;  Q4L6A1, DAPB_STAHJ ;
DR   Q49XJ8, DAPB_STAS1 ;  Q82K82, DAPB_STRAW ;  O86836, DAPB_STRCO ;
DR   A8AX95, DAPB_STRGC ;  B1VXZ4, DAPB_STRGG ;  B4SHT7, DAPB_STRM5 ;
DR   B2FQ70, DAPB_STRMK ;  Q8DUL9, DAPB_STRMU ;  Q04JJ1, DAPB_STRP2 ;
DR   B5E6K0, DAPB_STRP4 ;  C1C8E8, DAPB_STRP7 ;  B1ICX7, DAPB_STRPI ;
DR   B8ZLL9, DAPB_STRPJ ;  P63895, DAPB_STRPN ;  B2IR75, DAPB_STRPS ;
DR   P63896, DAPB_STRR6 ;  A4W0U7, DAPB_STRS2 ;  A3CMU3, DAPB_STRSV ;
DR   A4VUK5, DAPB_STRSY ;  Q5M154, DAPB_STRT1 ;  Q5M5P2, DAPB_STRT2 ;
DR   Q03M29, DAPB_STRTD ;  B9DRX8, DAPB_STRU0 ;  C1CFE0, DAPB_STRZJ ;
DR   C1CLQ6, DAPB_STRZP ;  C1CSH7, DAPB_STRZT ;  Q30PD7, DAPB_SULDN ;
DR   A6Q6T6, DAPB_SULNB ;  Q67P64, DAPB_SYMTH ;  Q2LTA0, DAPB_SYNAS ;
DR   Q31LA3, DAPB_SYNE7 ;  A0LEA6, DAPB_SYNFM ;  B1XIL4, DAPB_SYNP2 ;
DR   Q5N0M4, DAPB_SYNP6 ;  Q7U807, DAPB_SYNPX ;  A5GSL5, DAPB_SYNR3 ;
DR   Q3AYN5, DAPB_SYNS9 ;  Q3AIK8, DAPB_SYNSC ;  Q0AXH2, DAPB_SYNWW ;
DR   P72642, DAPB_SYNY3 ;  C5BQ31, DAPB_TERTT ;  B7IF14, DAPB_THEAB ;
DR   Q8DHH2, DAPB_THEEB ;  Q47RU3, DAPB_THEFY ;  A6LP59, DAPB_THEM4 ;
DR   Q9X1K8, DAPB_THEMA ;  B9K866, DAPB_THENN ;  A5IM63, DAPB_THEP1 ;
DR   B9KY70, DAPB_THERP ;  B1LBR0, DAPB_THESQ ;  Q8RBI6, DAPB_THETN ;
DR   Q3SJS2, DAPB_THIDA ;  B8GNX3, DAPB_THISH ;  C4LCT8, DAPB_TOLAT ;
DR   Q10YI1, DAPB_TRIEI ;  A5F5N9, DAPB_VIBC3 ;  Q9KPH7, DAPB_VIBCH ;
DR   C3LQT6, DAPB_VIBCM ;  Q5E7N0, DAPB_VIBF1 ;  B5FA64, DAPB_VIBFM ;
DR   A7MXR0, DAPB_VIBHB ;  Q87SF5, DAPB_VIBPA ;  B7VJ13, DAPB_VIBSL ;
DR   Q8DEM0, DAPB_VIBVU ;  Q7MNU2, DAPB_VIBVY ;  Q8D3H6, DAPB_WIGBR ;
DR   Q73I13, DAPB_WOLPM ;  B3CN84, DAPB_WOLPP ;  Q7MA63, DAPB_WOLSU ;
DR   Q5GTA6, DAPB_WOLTR ;  C0R2S2, DAPB_WOLWR ;  Q8PLE0, DAPB_XANAC ;
DR   Q3BUC6, DAPB_XANC5 ;  Q4UU71, DAPB_XANC8 ;  B0RSP5, DAPB_XANCB ;
DR   Q8P9L3, DAPB_XANCP ;  B2I841, DAPB_XYLF2 ;  Q9PEC3, DAPB_XYLFA ;
DR   B0U565, DAPB_XYLFM ;  Q87EC0, DAPB_XYLFT ;  A1JJE5, DAPB_YERE8 ;
DR   A7FMD2, DAPB_YERP3 ;  Q1C0I8, DAPB_YERPA ;  B2K3N1, DAPB_YERPB ;
DR   Q8ZIL6, DAPB_YERPE ;  A9R003, DAPB_YERPG ;  Q1CMU5, DAPB_YERPN ;
DR   A4TQE9, DAPB_YERPP ;  Q66ER9, DAPB_YERPS ;  B1JKZ4, DAPB_YERPY ;
DR   Q5NPM9, DAPB_ZYMMO ;
//
ID   1.3.1.27
DE   2-hexadecenal reductase.
AN   2-alkenal reductase.
CA   Hexadecanal + NADP(+) = 2-trans-hexadecenal + NADPH.
CC   -!- Specific for long chain 2-trans- and 2-cis-alkenals, with chain
CC       length optimum around 14 to 16 carbon atoms.
//
ID   1.3.1.28
DE   2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase.
AN   2,3-DHB dehydrogenase.
CA   2,3-dihydro-2,3-dihydroxybenzoate + NAD(+) = 2,3-dihydroxybenzoate +
CA   NADH.
CC   -!- Formerly EC 1.1.1.109.
PR   PROSITE; PDOC00060;
DR   P39071, DHBA_BACSU ;  P15047, ENTA_ECOLI ;  Q56632, VIBA_VIBCH ;
//
ID   1.3.1.29
DE   Cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase.
AN   Cis-dihydrodiol naphthalene dehydrogenase.
AN   Cis-naphthalene dihydrodiol dehydrogenase.
CA   Cis-1,2-dihydronaphthalene-1,2-diol + NAD(+) = naphthalene-1,2-diol +
CA   NADH.
CC   -!- Also acts, at half the rate, on cis-anthracene dihydrodiol and cis-
CC       phenanthrene dihydrodiol.
DR   P0A169, NAHB_PSEPU ;  P0A170, NAHB_PSEU8 ;
//
ID   1.3.1.30
DE   Progesterone 5-alpha-reductase.
AN   Steroid 5-alpha-reductase.
CA   5-alpha-pregnan-3,20-dione + NADP(+) = progesterone + NADPH.
CC   -!- Testosterone and 20-alpha-hydroxy-4-pregn-3-one can act in place of
CC       progesterone.
//
ID   1.3.1.31
DE   2-enoate reductase.
AN   Enoate reductase.
CA   Butanoate + NAD(+) = 2-butenoate + NADH.
CF   FAD; Iron-sulfur.
CC   -!- Acts, in the reverse direction, on a wide range of alkyl and aryl
CC       alpha-beta-unsaturated carboxylate ions; 2-butenoate was the best
CC       substrate tested.
DR   P11887, 2ENR_CLOTY ;  P40952, KYE1_KLULA ;
//
ID   1.3.1.32
DE   Maleylacetate reductase.
AN   Maleolylacetate reductase.
CA   3-oxoadipate + NAD(P)(+) = 2-maleylacetate + NAD(P)H.
DR   O87612, CLCE_PSEAE ;  O30847, CLCE_PSESB ;  O84992, MACA1_RHOOP;
DR   P56870, MACA2_RHOOP;  P27101, TCBF_PSESQ ;  P27137, TFDF1_CUPPJ;
DR   P94135, TFDF2_CUPPJ;  Q93T12, TFDF_DELAC ;  Q45072, TFTE_BURCE ;
//
ID   1.3.1.33
DE   Protochlorophyllide reductase.
AN   NADPH-protochlorophyllide oxidoreductase.
AN   Protochlorophyllide oxidoreductase.
CA   Chlorophyllide a + NADP(+) = protochlorophyllide + NADPH.
CC   -!- Catalyzes a light-dependent trans-reduction of the D-ring of
CC       protochlorophyllide; the product has the (7S,8S)-configuration.
DR   Q42536, PORA_ARATH ;  Q41249, PORA_CUCSA ;  P13653, PORA_HORVU ;
DR   Q7XKF3, PORA_ORYSJ ;  Q41578, PORA_WHEAT ;  P21218, PORB_ARATH ;
DR   Q42850, PORB_HORVU ;  Q8W3D9, PORB_ORYSJ ;  O48741, PORC_ARATH ;
DR   P15904, POR_AVESA  ;  Q39617, POR_CHLRE  ;  Q9SDT1, POR_DAUCA  ;
DR   O80333, POR_MARPA  ;  Q01289, POR_PEA    ;  O66148, POR_PLEBO  ;
DR   Q59987, POR_SYNY3  ;
//
ID   1.3.1.34
DE   2,4-dienoyl-CoA reductase (NADPH).
AN   4-enoyl-CoA reductase (NADPH).
CA   Trans-2,3-didehydroacyl-CoA + NADP(+) = trans,trans-2,3,4,5-
CA   tetradehydroacyl-CoA + NADPH.
CC   -!- Best substrates for reduction contain a 2,4-diene structure with
CC       chain length C(8) or C(10).
PR   PROSITE; PDOC00060;
DR   Q9LTV6, DECR2_ARATH;  Q6NV34, DECR2_DANRE;  Q9NUI1, DECR2_HUMAN;
DR   Q9WV68, DECR2_MOUSE;  Q5RBV3, DECR2_PONAB;  Q9Z2M4, DECR2_RAT  ;
DR   Q16698, DECR_HUMAN ;  Q9CQ62, DECR_MOUSE ;  Q64591, DECR_RAT   ;
DR   O34717, FADH_BACSU ;  P42593, FADH_ECOLI ;  P32573, SPS19_YEAST;
//
ID   1.3.1.35
DE   Phosphatidylcholine desaturase.
AN   Linoleate synthase.
AN   Oleate desaturase.
AN   Oleoyl-CoA desaturase.
CA   1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + NAD(+) = 1-acyl-2-
CA   linoleoyl-sn-glycero-3-phosphocholine + NADH.
CC   -!- Also desaturates phosphatidylcholine containing the oleoyl group on
CC       O-2 of the glycerol residue.
//
ID   1.3.1.36
DE   Geissoschizine dehydrogenase.
CA   Geissoschizine + NADP(+) = 4,21-dehydrogeissoschizine + NADPH.
CC   -!- Involved in the interconversion of heteroyohimbine alkaloids in
CC       Catharanthus roseus.
//
ID   1.3.1.37
DE   Cis-2-enoyl-CoA reductase (NADPH).
CA   Acyl-CoA + NADP(+) = cis-2,3-dehydroacyl-CoA + NADPH.
CC   -!- Not identical with EC 1.3.1.38 (cf. EC 1.3.1.8).
//
ID   1.3.1.38
DE   Trans-2-enoyl-CoA reductase (NADPH).
CA   Acyl-CoA + NADP(+) = trans-2,3-dehydroacyl-CoA + NADPH.
CC   -!- Not identical with EC 1.3.1.37 (cf. EC 1.3.1.8).
PR   PROSITE; PDOC00060;
DR   Q757U3, ETR1_ASHGO ;  Q6FXN7, ETR1_CANGA ;  Q8WZM3, ETR1_CANTR ;
DR   Q6BLV6, ETR1_DEBHA ;  Q6CIR6, ETR1_KLULA ;  Q10488, ETR1_SCHPO ;
DR   Q6CBE4, ETR1_YARLI ;  P38071, ETR1_YEAST ;  Q8WZM4, ETR2_CANTR ;
DR   Q6BV30, ETR2_DEBHA ;  O45903, MECR1_CAEEL;  Q9XXC8, MECR2_CAEEL;
DR   Q8LCU7, MECR_ARATH ;  Q7YS70, MECR_BOVIN ;  Q6GQN8, MECR_DANRE ;
DR   Q54YT4, MECR_DICDI ;  Q9V6U9, MECR_DROME ;  Q9BV79, MECR_HUMAN ;
DR   Q9DCS3, MECR_MOUSE ;  Q9Z311, MECR_RAT   ;  Q28GQ2, MECR_XENTR ;
DR   Q9JIF5, PECR_CAVPO ;  Q9BY49, PECR_HUMAN ;  Q99MZ7, PECR_MOUSE ;
DR   Q5RCH8, PECR_PONAB ;  Q9WVK3, PECR_RAT   ;  Q3ZCD7, TECR_BOVIN ;
DR   Q55C17, TECR_DICDI ;  Q9NZ01, TECR_HUMAN ;  Q9CY27, TECR_MOUSE ;
DR   Q64232, TECR_RAT   ;  Q99190, TSC13_YEAST;  O94511, YN67_SCHPO ;
//
ID   1.3.1.39
DE   Enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific).
AN   Acyl-ACP dehydrogenase.
CA   Acyl-[acyl-carrier-protein] + NADP(+) = trans-2,3-dehydroacyl-[acyl-
CA   carrier-protein] + NADPH.
CC   -!- The liver enzyme is A-specific with respect to NADP(+) (cf.
CC       EC 1.3.1.10).
//
ID   1.3.1.40
DE   2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase.
CA   2,6-dioxo-6-phenylhexanoate + NADP(+) = 2-hydroxy-6-oxo-6-phenylhexa-2,4-
CA   dienoate + NADPH.
CC   -!- Broad specificity; reduces a number of compounds produced by
CC       Pseudomonas from aromatic hydrocarbons by ring fission.
//
ID   1.3.1.41
DE   Xanthommatin reductase.
CA   5,12-dihydroxanthommatin + NAD(+) = xanthommatin + NADH.
CC   -!- From Drosophila melanogaster.
//
ID   1.3.1.42
DE   12-oxophytodienoate reductase.
CA   8-((1R,2R)-3-oxo-2-((Z)-pent-2-enyl)cyclopentyl)octanoate + NADP(+) =
CA   (15Z)-12-oxophyto-10,15-dienoate + NADPH.
CC   -!- Involved in the conversion of linolenate into jasmonate in Zea mays.
DR   Q8LAH7, OPR1_ARATH ;  Q84QK0, OPR1_ORYSJ ;  Q9XG54, OPR1_SOLLC ;
DR   Q8GYB8, OPR2_ARATH ;  Q9FUP0, OPR3_ARATH ;  Q9FEW9, OPR3_SOLLC ;
DR   Q6Z965, OPR7_ORYSJ ;
//
ID   1.3.1.43
DE   Arogenate dehydrogenase.
AN   Arogenic dehydrogenase.
AN   Cyclohexadienyl dehydrogenase.
AN   L-arogenate:NAD(+) oxidoreductase.
AN   Pretyrosine dehydrogenase.
CA   L-arogenate + NAD(+) = L-tyrosine + NADH + CO(2).
CC   -!- See also EC 1.3.1.12, EC 1.3.1.78 and EC 1.3.1.79.
PR   PROSITE; PDOC51176;
DR   Q04983, TYRC_ZYMMO ;
//
ID   1.3.1.44
DE   Trans-2-enoyl-CoA reductase (NAD(+)).
CA   Acyl-CoA + NAD(+) = trans-didehydroacyl-CoA + NADH.
CC   -!- The enzyme from Euglena gracilis acts on crotonoyl-CoA and, more
CC       slowly, on trans-hex-2-enoyl-CoA and trans-oct-2-enoyl-CoA.
DR   Q5EU90, TER_EUGGR  ;
//
ID   1.3.1.45
DE   2'-hydroxyisoflavone reductase.
CA   Vestitone + NADP(+) = 2'-hydroxyformononetin + NADPH.
CC   -!- In the reverse reaction, a 2'-hydroxyisoflavone is reduced to an
CC       isoflavanone; 2'-hydroxypseudobaptigenin also acts.
CC   -!- Involved in the biosynthesis of the pterocarpin phytoalexins
CC       medicarpin and maackiain.
DR   Q00016, IFR_CICAR  ;  P52575, IFR_MEDSA  ;  P52576, IFR_PEA    ;
//
ID   1.3.1.46
DE   Biochanin-A reductase.
CA   Dihydrobiochanin A + NADP(+) = biochanin A + NADPH.
CC   -!- Some other isoflavones are reduced to the corresponding
CC       isoflavanones.
//
ID   1.3.1.47
DE   Alpha-santonin 1,2-reductase.
CA   1,2-dihydrosantonin + NAD(P)(+) = alpha-santonin + NAD(P)H.
//
ID   1.3.1.48
DE   15-oxoprostaglandin 13-oxidase.
AN   15-oxo-Delta(13)-prostaglandin reductase.
AN   Prostaglandin 13-reductase.
CA   11-alpha-hydroxy-9,15-dioxoprost-5-enoate + NAD(P)(+) = (5Z)-(13E)-11-
CA   alpha-hydroxy-9,15-dioxoprosta-5,13-dienoate + NAD(P)H.
CC   -!- Reduces 15-oxoprostaglandins to 13,14-dihydro derivatives.
CC   -!- The enzyme from placenta is specific for NAD(+).
DR   Q3SZJ4, PTGR1_BOVIN;  Q9EQZ5, PTGR1_CAVPO;  Q14914, PTGR1_HUMAN;
DR   Q91YR9, PTGR1_MOUSE;  Q29073, PTGR1_PIG  ;  Q28719, PTGR1_RABIT;
DR   P97584, PTGR1_RAT  ;  Q32L99, PTGR2_BOVIN;  Q8N8N7, PTGR2_HUMAN;
DR   Q8VDQ1, PTGR2_MOUSE;  Q5R806, PTGR2_PONAB;  Q5BK81, PTGR2_RAT  ;
//
ID   1.3.1.49
DE   Cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase.
CA   (+)-cis-3,4-dihydrophenanthrene-3,4-diol + NAD(+) = phenanthrene-3,4-diol
CA   + NADH.
//
ID   1.3.1.50
DE   Transferred entry: 1.1.1.252.
//
ID   1.3.1.51
DE   2'-hydroxydaidzein reductase.
AN   2'-hydroxydihydrodaidzein:NADP(+) 2'-oxidoreductase.
AN   HDR.
AN   NADPH:2'-hydroxydaidzein oxidoreductase.
CA   2'-hydroxy-2,3-dihydrodaidzein + NADP(+) = 2'-hydroxydaidzein + NADPH.
CC   -!- In the reverse reaction, the 2'-hydroxyisoflavone
CC       (2'-hydroxydaidzein) is reduced to an isoflavanone.
CC   -!- Also acts on 2'-hydroxyformononetin and to a small extent on
CC       2'-hydroxygenistein.
CC   -!- Involved in the biosynthesis of the phytoalexin glyceollin.
CC   -!- The isoflavones biochanin A, daidzein and genestein as well as the
CC       flavonoids apigenin, kaempferol and quercetin do not act as
CC       substrates.
//
ID   1.3.1.52
DE   2-methyl-branched-chain-enoyl-CoA reductase.
CA   2-methylbutanoyl-CoA + NAD(+) = 2-methylcrotonoyl-CoA + NADH.
CF   FAD.
CC   -!- From Ascaris suum.
CC   -!- The reaction proceeds only in the presence of another flavoprotein
CC       ('electron-transferring flavoprotein').
//
ID   1.3.1.53
DE   (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase.
AN   (1R,2S)-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase.
AN   DCD dehydrogenase.
AN   Dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase.
CA   (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+) =
CA   3,4-dihydroxybenzoate + CO(2) + NADH.
CF   Fe(2+).
CC   -!- Involved in the terephthalate degradation pathway in bacteria.
CC   -!- Formerly EC 1.3.1.61.
//
ID   1.3.1.54
DE   Precorrin-6A reductase.
AN   Precorrin-6X reductase.
AN   Precorrin-6Y:NADP(+) oxidoreductase.
CA   Precorrin-6B + NADP(+) = precorrin-6A + NADPH.
PR   PROSITE; PDOC51014;
DR   Q10680, COBK_MYCTU ;  P21920, COBK_PSEDE ;  O68098, COBK_RHOCB ;
DR   Q53139, COBK_RHOER ;
//
ID   1.3.1.55
DE   Deleted entry.
//
ID   1.3.1.56
DE   Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase.
AN   2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase.
AN   Biphenyl-2,3-dihydro-2,3-diol dehydrogenase.
CA   Cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD(+) = biphenyl-2,3-diol +
CA   NADH.
CC   -!- Catalyzes the second step in the biphenyl degradation pathway in
CC       bacteria.
PR   PROSITE; PDOC00060;
DR   P47227, BPHB_BURXL ;  Q46381, BPHB_COMTE ;  P08694, BPHB_PSEPS ;
DR   P72220, BPHB_PSEPU ;  P50206, BPHB_PSES1 ;  P47230, BPHB_RHOGO ;
//
ID   1.3.1.57
DE   Phloroglucinol reductase.
CA   Dihydrophloroglucinol + NADP(+) = phloroglucinol + NADPH.
CC   -!- Involved in the gallate anaerobic degradation pathway in bacteria.
DR   P57793, PHGR_EUBOX ;
//
ID   1.3.1.58
DE   2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase.
AN   Biphenyl-2,3-dihydro-2,3-diol dehydrogenase.
CA   Cis-5,6-dihydroxy-4-isopropylcyclohexa-1,3-dienecarboxylate + NAD(+) =
CA   2,3-dihydroxy-p-cumate + NADH.
CC   -!- Involved in the p-cymene and p-cumate degradation pathways in
CC       Pseudomonas putida.
PR   PROSITE; PDOC00060;
DR   A5W4G5, CMTB_PSEP1 ;  P0C622, CMTB_PSEPU ;
//
ID   1.3.1.59
DE   Deleted entry.
//
ID   1.3.1.60
DE   Dibenzothiophene dihydrodiol dehydrogenase.
CA   Cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene + NAD(+) = 1,2-
CA   dihydroxydibenzothiophene + NADH.
CC   -!- Involved in the dibenzothiophene degradation pathway in bacteria.
DR   P0A169, NAHB_PSEPU ;  P0A170, NAHB_PSEU8 ;
//
ID   1.3.1.61
DE   Deleted entry.
//
ID   1.3.1.62
DE   Pimeloyl-CoA dehydrogenase.
CA   Pimeloyl-CoA + NAD(+) = 6-carboxyhex-2-enoyl-CoA + NADH.
CC   -!- Involved in the benzoate degradation (anaerobic) pathway in bacteria.
//
ID   1.3.1.63
DE   2,4-dichlorobenzoyl-CoA reductase.
CA   4-chlorobenzoyl-CoA + NADP(+) + chloride = 2,4-dichlorobenzoyl-CoA +
CA   NADPH.
CC   -!- Acts in the reverse direction to form part of the 2,4-
CC       dichlorobenzoate degradation pathway in bacteria.
//
ID   1.3.1.64
DE   Phthalate 4,5-cis-dihydrodiol dehydrogenase.
CA   Cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD(+) = 4,5-
CA   dihydroxyphthalate + NADH.
CC   -!- Involved in the phthalate degradation pathway in bacteria.
//
ID   1.3.1.65
DE   5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase.
CA   5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD(+) = 5,6-
CA   dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH.
CC   -!- Acts in the reverse direction to form part of the 3-methylquinoline
CC       degradation pathway in bacteria.
//
ID   1.3.1.66
DE   Cis-dihydroethylcatechol dehydrogenase.
CA   Cis-1,2-dihydro-3-ethylcatechol + NAD(+) = 3-ethylcatechol + NADH.
CC   -!- Involved in the ethylbenzene degradation pathway in bacteria.
//
ID   1.3.1.67
DE   Cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate
DE   dehydrogenase.
CA   Cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NAD(P)(+) =
CA   4-methylcatechol + NAD(P)H + CO(2).
CC   -!- Involved in the p-xylene degradation pathway in bacteria.
//
ID   1.3.1.68
DE   1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase.
CA   1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate + NAD(+) =
CA   3-methylcatechol + NADH + CO(2).
CC   -!- Involved in the o-xylene degradation pathway in bacteria.
//
ID   1.3.1.69
DE   Zeatin reductase.
CA   Dihydrozeatin + NADP(+) = zeatin + NADPH.
CC   -!- Previously classified erroneously as EC 1.1.1.242.
//
ID   1.3.1.70
DE   Delta(14)-sterol reductase.
AN   C-14 sterol reductase.
AN   Sterol C14-reductase.
CA   4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NADP(+) = 4,4-
CA   dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol + NADPH.
CC   -!- Acts on a range of steroids with a 14(15)-double bond.
DR   Q9LDR4, ERG24_ARATH;  P78575, ERG24_ASCIM;  Q8WMV1, ERG24_BOVIN;
DR   Q54PP1, ERG24_DICDI;  Q01447, ERG24_FUSSO;  O76062, ERG24_HUMAN;
DR   Q71KT5, ERG24_MOUSE;  P38670, ERG24_NEUCR;  Q09195, ERG24_SCHPO;
DR   O13597, ERG24_SEPLY;  P32462, ERG24_YEAST;
//
ID   1.3.1.71
DE   Delta(24(24(1)))-sterol reductase.
AN   C-24(28) sterol reductase.
AN   Sterol Delta(24(28))-methylene reductase.
AN   Sterol Delta(24(28))-reductase.
CA   Ergosterol + NADP(+) = ergosta-5,7,22,24(24(1))-tetraen-3-beta-ol +
CA   NADPH.
CC   -!- Acts on a range of steroids with a 24(24(1))-double bond.
DR   P25340, ERG4_YEAST ;  P36209, STS1_SCHPO ;
//
ID   1.3.1.72
DE   Delta(24)-sterol reductase.
AN   Lanosterol Delta(24)-reductase.
CA   5-alpha-cholest-7-en-3-beta-ol + NADP(+) = 5-alpha-cholesta-7,24-dien-3-
CA   beta-ol + NADPH.
CC   -!- Acts on a range of steroids with a 24(25)-double bond, including
CC       lanosterol, desmosterol and zymosterol.
DR   Q15392, DHC24_HUMAN;  Q60HC5, DHC24_MACFA;  Q8VCH6, DHC24_MOUSE;
DR   Q5BQE6, DHC24_RAT  ;  Q39085, DIM_ARATH  ;  P93472, DIM_PEA    ;
//
ID   1.3.1.73
DE   1,2-dihydrovomilenine reductase.
CA   17-O-acetylnorajmaline + NADP(+) = 1,2-dihydrovomilenine + NADPH.
CC   -!- Forms part of the ajmaline biosynthesis pathway.
//
ID   1.3.1.74
DE   2-alkenal reductase.
AN   NAD(P)H-dependent alkenal/one oxidoreductase.
AN   NADPH:2-alkenal alpha,beta-hydrogenase.
CA   n-alkanal + NAD(P)(+) = alk-2-enal + NAD(P)H.
CC   -!- Highly specific for 4-hydroxy-non-2-enal and non-2-enal.
CC   -!- 2-alkenals of shorter chain have lower affinities.
CC   -!- Exhibits high activities also for 2-alkenones such as but-3-en-2-one
CC       and pent-3-en-2-one.
CC   -!- Inactive with cyclohex-2-en-1-one and 12-oxophytodienoic acid.
CC   -!- Involved in the detoxification of alpha,beta-unsaturated aldehydes
CC       and ketones.
DR   Q39172, P1_ARATH   ;  Q39173, P2_ARATH   ;  Q3SZJ4, PTGR1_BOVIN;
DR   Q9EQZ5, PTGR1_CAVPO;  Q14914, PTGR1_HUMAN;  Q91YR9, PTGR1_MOUSE;
DR   Q29073, PTGR1_PIG  ;  Q28719, PTGR1_RABIT;  P97584, PTGR1_RAT  ;
//
ID   1.3.1.75
DE   Divinyl chlorophyllide a 8-vinyl-reductase.
AN   4VCR.
AN   [4-vinyl]chlorophyllide a reductase.
CA   Chlorophyllide a + NADP(+) = divinyl chlorophyllide a + NADPH.
CC   -!- Also reduces divinyl protochlorophyllide to protochlorophyllide in
CC       some species, providing an alternative pathway.
//
ID   1.3.1.76
DE   Precorrin-2 dehydrogenase.
AN   Precorrin-2 oxidase.
CA   Precorrin-2 + NAD(+) = sirohydrochlorin + NADH.
CC   -!- Catalyzes the second of three steps leading to the formation of
CC       siroheme from uroporphyrinogen III.
CC   -!- The first step involves the donation of two S-adenosyl-L-methionine-
CC       derived methyl groups to carbons 2 and 7 of uroporphyrinogen III to
CC       form precorrin-2 (EC 2.1.1.107) and the third step involves the
CC       chelation of ferrous iron to sirohydrochlorin to form siroheme
CC       (EC 4.99.1.4).
CC   -!- In Saccharomyces cerevisiae, the last two steps are carried out by a
CC       single bifunctional enzyme, Met8p.
CC   -!- In some bacteria, steps 1-3 are catalyzed by a single multifunctional
CC       protein called CysG, whereas in Bacillus megaterium, three separate
CC       enzymes carry out each of the steps, with SirC being responsible for
CC       the above reaction.
DR   A0KLD7, CYSG1_AERHH;  A4SHL4, CYSG1_AERS4;  A7MJ67, CYSG1_ENTS8;
DR   Q6D1A4, CYSG1_ERWCT;  A1WWP8, CYSG1_HALHL;  A6TD45, CYSG1_KLEP7;
DR   A8G9Y3, CYSG1_SERP5;  A1JJS8, CYSG1_YERE8;  A7FLY4, CYSG1_YERP3;
DR   Q1CLS2, CYSG1_YERPN;  A4TGU8, CYSG1_YERPP;  Q66EC9, CYSG1_YERPS;
DR   A0KP37, CYSG2_AERHH;  A4SRH0, CYSG2_AERS4;  A7MKK9, CYSG2_ENTS8;
DR   Q6CZS0, CYSG2_ERWCT;  A1WYD5, CYSG2_HALHL;  A6TF07, CYSG2_KLEP7;
DR   A8GKQ1, CYSG2_SERP5;  A1JSB7, CYSG2_YERE8;  A7FNS9, CYSG2_YERP3;
DR   Q1CCP6, CYSG2_YERPN;  A4TPZ1, CYSG2_YERPP;  Q664M6, CYSG2_YERPS;
DR   A0KQJ4, CYSG3_AERHH;  Q6F8G6, CYSG_ACIAD ;  B3GZA0, CYSG_ACTP7 ;
DR   B0BTC2, CYSG_ACTPJ ;  A6VPZ6, CYSG_ACTSZ ;  Q0VQ05, CYSG_ALCBS ;
DR   Q0A812, CYSG_ALHEH ;  C1DKY7, CYSG_AZOVD ;  Q1LTP4, CYSG_BAUCH ;
DR   Q7VQG9, CYSG_BLOFL ;  Q493N1, CYSG_BLOPB ;  Q2KWB0, CYSG_BORA1 ;
DR   Q7WMM4, CYSG_BORBR ;  Q7WB57, CYSG_BORPA ;  A9HZV6, CYSG_BORPD ;
DR   Q7VZ77, CYSG_BORPE ;  P57500, CYSG_BUCAI ;  Q7NZV7, CYSG_CHRVO ;
DR   A8AQS4, CYSG_CITK8 ;  A7ZSP4, CYSG_ECO24 ;  B7UK79, CYSG_ECO27 ;
DR   B7MCY5, CYSG_ECO45 ;  B7L4P2, CYSG_ECO55 ;  P0AEA9, CYSG_ECO57 ;
DR   B5YTS6, CYSG_ECO5E ;  B7NMD7, CYSG_ECO7I ;  B7N1F1, CYSG_ECO81 ;
DR   B7M1S1, CYSG_ECO8A ;  C4ZUM4, CYSG_ECOBW ;  B1X716, CYSG_ECODH ;
DR   A8A5H5, CYSG_ECOHS ;  A1AGQ2, CYSG_ECOK1 ;  Q0TC92, CYSG_ECOL5 ;
DR   Q8FCW8, CYSG_ECOL6 ;  B1IP96, CYSG_ECOLC ;  P0AEA8, CYSG_ECOLI ;
DR   B7NDX8, CYSG_ECOLU ;  B6I2S7, CYSG_ECOSE ;  B1LHG9, CYSG_ECOSM ;
DR   Q1R5R3, CYSG_ECOUT ;  C5BGP8, CYSG_EDWI9 ;  A4WFH1, CYSG_ENT38 ;
DR   B7LS75, CYSG_ESCF3 ;  A9H259, CYSG_GLUDA ;  Q5FP95, CYSG_GLUOX ;
DR   Q2SJB7, CYSG_HAHCH ;  Q65T49, CYSG_MANSM ;  Q606C9, CYSG_METCA ;
DR   Q1H3L5, CYSG_METFK ;  A9LZ77, CYSG_NEIM0 ;  P57001, CYSG_NEIMA ;
DR   P95370, CYSG_NEIMB ;  A1KU10, CYSG_NEIMF ;  Q0AHC1, CYSG_NITEC ;
DR   Q820Q4, CYSG_NITEU ;  Q2Y6L7, CYSG_NITMU ;  Q3JCS0, CYSG_NITOC ;
DR   Q7N8L2, CYSG_PHOLL ;  Q6LM67, CYSG_PHOPR ;  Q48H75, CYSG_PSE14 ;
DR   Q15YU1, CYSG_PSEA6 ;  A6V4H6, CYSG_PSEA7 ;  B7UW11, CYSG_PSEA8 ;
DR   Q02NA3, CYSG_PSEAB ;  Q9I0M7, CYSG_PSEAE ;  Q1IBC9, CYSG_PSEE4 ;
DR   Q4K9V8, CYSG_PSEF5 ;  C3JY53, CYSG_PSEFS ;  Q3ILQ9, CYSG_PSEHT ;
DR   A4XUX3, CYSG_PSEMY ;  A5W1H7, CYSG_PSEP1 ;  Q3KA85, CYSG_PSEPF ;
DR   Q88FT3, CYSG_PSEPK ;  B1JBD9, CYSG_PSEPW ;  Q87ZT0, CYSG_PSESM ;
DR   Q4ZRL6, CYSG_PSEU2 ;  A4VLU6, CYSG_PSEU5 ;  Q4FSU1, CYSG_PSYA2 ;
DR   Q1QAX7, CYSG_PSYCK ;  A1SRP9, CYSG_PSYIN ;  A5WEG6, CYSG_PSYWF ;
DR   A1AVU5, CYSG_RUTMC ;  Q21K21, CYSG_SACD2 ;  B5F8J0, CYSG_SALA4 ;
DR   A9MME5, CYSG_SALAR ;  Q57IZ5, CYSG_SALCH ;  B5FJQ1, CYSG_SALDC ;
DR   B5R2C7, CYSG_SALEP ;  B5R7N6, CYSG_SALG2 ;  B4TKQ4, CYSG_SALHS ;
DR   B4SVI1, CYSG_SALNS ;  Q5PLV8, CYSG_SALPA ;  A9MT45, CYSG_SALPB ;
DR   C0Q0F3, CYSG_SALPC ;  B5BH22, CYSG_SALPK ;  B4TY38, CYSG_SALSV ;
DR   Q8Z201, CYSG_SALTI ;  P25924, CYSG_SALTY ;  B2U3H4, CYSG_SHIB3 ;
DR   Q31VS0, CYSG_SHIBS ;  Q32AZ8, CYSG_SHIDS ;  Q0SZU8, CYSG_SHIF8 ;
DR   Q83JB3, CYSG_SHIFL ;  Q3YWQ3, CYSG_SHISS ;  Q2NVN0, CYSG_SODGM ;
DR   Q31GG8, CYSG_THICR ;  Q3SG32, CYSG_THIDA ;  B8GUD3, CYSG_THISH ;
DR   C4LAG5, CYSG_TOLAT ;  A5CXE4, CYSG_VESOH ;  B2I985, CYSG_XYLF2 ;
DR   Q9PF46, CYSG_XYLFA ;  B0U4X0, CYSG_XYLFM ;  Q87AI5, CYSG_XYLFT ;
DR   Q1C2P9, CYSG_YERPA ;  Q74Y23, CYSG_YERPE ;  Q5NRM4, CYSG_ZYMMO ;
DR   O14172, MET8_SCHPO ;  P15807, MET8_YEAST ;  P61818, SIRC_BACME ;
DR   O34813, SIRC_BACSU ;
//
ID   1.3.1.77
DE   Anthocyanidin reductase.
AN   ANR.
CA   A flavan-3-ol + 2 NAD(P)(+) = an anthocyanidin + 2 NAD(P)H.
CC   -!- Forms 2,3-cis-flavan-3-ols.
CC   -!- The isomeric 2,3-trans-flavan-3-ols are formed from flavan-3,4-diols
CC       by EC 1.17.1.3.
CC   -!- While the enzyme from the legume Medicago truncatula (MtANR) uses
CC       both NADPH and NADH as reductant, that from the crucifer Arabidopsis
CC       thaliana (AtANR) uses only NADPH.
CC   -!- Also, while the substrate preference of MtANR is
CC       cyanidin>pelargonidin>delphinidin, the reverse preference is found
CC       with AtANR.
DR   Q9SEV0, BAN_ARATH  ;
//
ID   1.3.1.78
DE   Arogenate dehydrogenase (NADP(+)).
AN   Arogenic dehydrogenase.
AN   Pretyrosine dehydrogenase.
AN   TyrA(a).
AN   TyrAAT1.
AN   TyrAAT2.
CA   L-arogenate + NADP(+) = L-tyrosine + NADPH + CO(2).
CC   -!- Unlike EC 1.3.1.43 and EC 1.3.1.79, this enzyme has a strict
CC       requirement for NADP(+).
CC   -!- The enzyme from Synechocystis sp. PCC 6803 and the isoform TyrAAT1
CC       cannot use prephenate as a substrate, while the isoform TyrAAT2 can
CC       use it only very poorly.
DR   Q944B6, TYRA1_ARATH;  Q9LMR3, TYRA2_ARATH;
//
ID   1.3.1.79
DE   Arogenate dehydrogenase (NAD(P)(+)).
AN   Arogenic dehydrogenase.
AN   Cyclohexadienyl dehydrogenase.
AN   Pretyrosine dehydrogenase.
CA   L-arogenate + NAD(P)(+) = L-tyrosine + NAD(P)H + CO(2).
CC   -!- See also EC 1.3.1.12, EC 1.3.1.43 and EC 1.3.1.78.
//
ID   1.3.1.80
DE   Red chlorophyll catabolite reductase.
AN   RCC reductase.
AN   RCCR.
AN   Red Chl catabolite reductase.
CA   Primary fluorescent chlorophyll catabolite + NADP(+) = red chlorophyll
CA   catabolite + NADPH.
CC   -!- Chlorophyll degradation is a characteristic symptom of leaf
CC       senescence and fruit ripening.
CC   -!- The reaction catalyzed by this enzyme requires reduced ferredoxin,
CC       which is generated either by NADPH through the pentose-phosphate
CC       pathway or by the action of photosystem I.
CC   -!- This reaction takes place without release of the substrate from
CC       EC 1.14.12.20.
CC   -!- Depending on the plant species used as the source of enzyme, one of
CC       two possible C-1 epimers of primary fluorescent chlorophyll
CC       catabolite (pFCC), pFCC-1 or pFCC-2, is normally formed, with all
CC       genera or species within a family producing the same isomer.
CC   -!- After modification and export, pFCCs are eventually imported into the
CC       vacuole, where the acidic environment causes their non-enzymic
CC       conversion into colorless breakdown products called non-fluorescent
CC       chlorophyll catabolites (NCCs).
DR   Q8LDU4, RCCR_ARATH ;  Q9MTQ6, RCCR_HORVU ;
//
ID   1.3.1.81
DE   (+)-pulegone reductase.
CA   (1) (-)-menthone + NADP(+) = (+)-pulegone + NADPH.
CA   (2) (+)-isomenthone + NADP(+) = (+)-pulegone + NADPH.
CC   -!- NADH cannot replace NADPH as reductant.
CC   -!- The Delta(8,9)-double bond of (+)-cis-isopulegone and the Delta(1,2)-
CC       double bond of (+-)-piperitone are not substrates.
CC   -!- The enzyme from peppermint (Mentha x piperita) converts (+)-pulegone
CC       into both (-)-menthone and (+)-isomenthone at a ratio of 70:30 for
CC       native enzyme but it does not catalyze the reverse reaction.
DR   Q6WAU0, PULR_MENPI ;
//
ID   1.3.1.82
DE   (-)-isopiperitenone reductase.
CA   (+)-cis-isopulegone + NADP(+) = (-)-isopiperitenone + NADPH.
CC   -!- The reaction occurs in the opposite direction to that shown above.
CC   -!- Participates in the menthol-biosynthesis pathway of Mentha plants.
CC   -!- (+)-pulegone, (+)-cis-isopulegone and (-)-menthone are not
CC       substrates.
CC   -!- Has a preference for NADPH as the reductant, with NADH being a poor
CC       substitute.
CC   -!- Highly regioselective for the reduction of the endocyclic 1,2-double
CC       bond, and is stereoselective, producing only the 1R-configured
CC       product.
PR   PROSITE; PDOC00060;
DR   Q6WAU1, IPIPR_MENPI;
//
ID   1.3.1.83
DE   Geranylgeranyl diphosphate reductase.
AN   Geranylgeranyl reductase.
CA   Phytyl diphosphate + 3 NADP(+) = geranylgeranyl diphosphate + 3 NADPH.
CC   -!- This enzyme also acts on geranylgeranyl-chlorophyll a.
CC   -!- The reaction occurs in three steps.
CC   -!- Which order the three double bonds are reduced is not known.
DR   P26172, BCHP_RHOCB ;  Q9CA67, CHLP_ARATH ;  Q6Z2T6, CHLP_ORYSJ ;
DR   Q55087, CHLP_SYNY3 ;  Q9ZS34, CHLP_TOBAC ;
//
ID   1.3.1.84
DE   Acrylyl-CoA reductase (NADPH).
CA   Propanoyl-CoA + NADP(+) = acrylyl-CoA + NADPH.
CF   Zinc.
CC   -!- Catalyzes a step in the 3-hydroxypropanoate/4-hydroxybutyrate cycle,
CC       an autotrophic CO(2) fixation pathway found in some thermoacidophilic
CC       archaea.
CC   -!- The reaction is catalyzed in the opposite direction to that shown.
CC   -!- The enzyme from Sulfolobus tokodaii does not act on either NADH or
CC       crotonyl-CoA.
CC   -!- Different from EC 1.3.1.8, which acts only on enoyl-CoA derivatives
CC       of carbon chain length 4 to 16.
PR   PROSITE; PDOC00058;
DR   A4YGN2, ACAR_METS5 ;  Q975C8, ACAR_SULTO ;
//
ID   1.3.1.85
DE   Crotonyl-CoA carboxylase/reductase.
AN   CCR.
AN   Crotonyl-CoA reductase (carboxylating).
CA   (2S)-ethylmalonyl-CoA + NADP(+) = (E)-but-2-enoyl-CoA + CO(2) + NADPH.
CC   -!- The reaction is catalyzed in the reverse direction.
CC   -!- This enzyme, isolated from the bacterium Rhodobacter sphaeroides,
CC       catalyzes (E)-but-2-enoyl-CoA-dependent oxidation of NADPH in the
CC       presence of CO(2).
CC   -!- When CO(2) is absent, the enzyme catalyzes the reduction of (E)-but-
CC       2-enoyl-CoA to butanoyl-CoA, but with only 10% of maximal activity
CC       (relative to (E)-but-2-enoyl-CoA carboxylation).
//
ID   1.3.1.86
DE   Crotonyl-CoA reductase.
AN   3-hydroxyacyl CoA reductase.
AN   Butyryl-CoA dehydrogenase.
AN   Enoyl-coenzyme A reductase.
AN   Ethylene reductase.
AN   Short-chain acyl-coenzyme A dehydrogenase.
AN   Unsaturated acyl coenzyme A reductase.
CA   Butanoyl-CoA + NADP(+) = (E)-but-2-enoyl-CoA + NADPH.
CC   -!- Catalyzes the reaction in the reverse direction.
CC   -!- This enzyme from Streptomyces collinus is specific for (E)-but-2-
CC       enoyl-CoA, and is proposed to provide butanoyl-CoA as a starter unit
CC       for straight-chain fatty acid biosynthesis.
//
ID   1.3.1.87
DE   3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase.
AN   Cis-dihydrodiol dehydrogenase; 2,3-dihydroxy-2,3-dihydro-phenylpropionate
AN   dehydrogenase.
CA   (1) 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD(+) =
CA   3-(2,3-dihydroxyphenyl)propanoate + NADH.
CA   (2) Cis-3-(2-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol + NAD(+) =
CA   trans-2,3-dihydroxycinnamate + NADH.
CC   -!- This enzyme catalyzes a step in the pathway of phenylpropanoid
CC       compounds degradation.
CC   -!- Formerly EC 1.3.1.n1.
DR   A7ZPY4, HCAB_ECO24 ;  B7LDD3, HCAB_ECO55 ;  Q8XA72, HCAB_ECO57 ;
DR   B5Z114, HCAB_ECO5E ;  B7NRJ0, HCAB_ECO7I ;  B7M7P4, HCAB_ECO8A ;
DR   C4ZXB6, HCAB_ECOBW ;  B1XB16, HCAB_ECODH ;  A8A347, HCAB_ECOHS ;
DR   B1IVT6, HCAB_ECOLC ;  P0CI31, HCAB_ECOLI ;  B7N6C8, HCAB_ECOLU ;
DR   P0CI32, HCAB_ECOLX ;  B6I5B4, HCAB_ECOSE ;  B1LNJ7, HCAB_ECOSM ;
DR   Q7N4V7, HCAB_PHOLL ;  Q31XU9, HCAB_SHIBS ;  Q0T1X8, HCAB_SHIF8 ;
DR   Q83QJ8, HCAB_SHIFL ;  Q3YZ12, HCAB_SHISS ;
//
ID   1.3.1.n1
DE   Transferred entry: 1.3.1.87.
//
ID   1.3.2.1
DE   Transferred entry: 1.3.8.1.
//
ID   1.3.2.2
DE   Transferred entry: 1.3.99.3.
//
ID   1.3.2.3
DE   L-galactonolactone dehydrogenase.
AN   Galactonolactone dehydrogenase.
AN   GLDase.
AN   GLDHase.
AN   L-galactono-gamma-lactone dehydrogenase.
CA   (1) L-galactono-1,4-lactone + 2 ferricytochrome c = L-ascorbate +
CA   2 ferrocytochrome c + 2 H(+).
CA   (2) L-ascorbate + 2 ferricytochrome c = L-dehydroascorbate +
CA   2 ferrocytochrome c + 2 H(+).
CC   -!- Catalyzes the final step in the biosynthesis of L-ascorbic acid in
CC       higher plants and in nearly all higher animals with the exception of
CC       primates and some birds.
CC   -!- Very specific for its substrate L-galactono-1,4-lactone as
CC       D-galactono-gamma-lactone, D-gulono-gamma-lactone, L-gulono-gamma-
CC       lactone, D-erythronic-gamma-lactone, D-xylonic-gamma-lactone,
CC       L-mannono-gamma-lactone, D-galactonate, D-glucuronate and D-gluconate
CC       are not substrates.
CC   -!- FAD, NAD(+), NADP(+) and O(2) (cf. EC 1.3.3.12) cannot act as
CC       electron acceptor.
DR   Q2RAP0, GLDH1_ORYSJ;  Q2QXY1, GLDH2_ORYSJ;  Q9SU56, GLDH_ARATH ;
DR   O47881, GLDH_BRAOL ;
//
ID   1.3.3.1
DE   Transferred entry: 1.3.98.1.
//
ID   1.3.3.2
DE   Transferred entry: 1.14.21.6.
//
ID   1.3.3.3
DE   Coproporphyrinogen oxidase.
AN   Coprogen oxidase.
AN   Coproporphyrinogen-III oxidase.
AN   Coproporphyrinogenase.
CA   Coproporphyrinogen-III + O(2) + 2 H(+) = protoporphyrinogen-IX + 2 CO(2)
CA   + 2 H(2)O.
CF   Iron.
PR   PROSITE; PDOC00783;
DR   Q8YZ37, HEM61_NOSS1;  Q8YX58, HEM62_NOSS1;  A0KEX7, HEM6_AERHH ;
DR   A4ST50, HEM6_AERS4 ;  B9J7B2, HEM6_AGRRK ;  Q8UD80, HEM6_AGRT5 ;
DR   B9JZ61, HEM6_AGRVS ;  Q0VTD7, HEM6_ALCBS ;  Q9LR75, HEM6_ARATH ;
DR   Q5P7I0, HEM6_AROAE ;  Q7WL80, HEM6_BORBR ;  Q7W7U0, HEM6_BORPA ;
DR   A9ITM7, HEM6_BORPD ;  Q7VWE7, HEM6_BORPE ;  Q89SC2, HEM6_BRAJA ;
DR   B2S710, HEM6_BRUA1 ;  Q2YS10, HEM6_BRUA2 ;  Q57BW7, HEM6_BRUAB ;
DR   A9M6L4, HEM6_BRUC2 ;  C0REI6, HEM6_BRUMB ;  P63850, HEM6_BRUME ;
DR   P63851, HEM6_BRUSU ;  B1YU52, HEM6_BURA4 ;  B1JW43, HEM6_BURCC ;
DR   B4E5R8, HEM6_BURCJ ;  Q0BD83, HEM6_BURCM ;  A9AJJ8, HEM6_BURM1 ;
DR   A3MI45, HEM6_BURM7 ;  A2S4B5, HEM6_BURM9 ;  Q62II8, HEM6_BURMA ;
DR   A1V2G0, HEM6_BURMS ;  A3NT46, HEM6_BURP0 ;  A3N7F7, HEM6_BURP6 ;
DR   B2T2A3, HEM6_BURPP ;  Q63VT1, HEM6_BURPS ;  Q39E99, HEM6_BURS3 ;
DR   Q142L8, HEM6_BURXL ;  B8GZX1, HEM6_CAUCN ;  Q9AAT8, HEM6_CAUCR ;
DR   B0T8D1, HEM6_CAUSK ;  Q1QTJ9, HEM6_CHRSD ;  Q7P012, HEM6_CHRVO ;
DR   A8ADF0, HEM6_CITK8 ;  A9KC01, HEM6_COXBN ;  A9NA93, HEM6_COXBR ;
DR   Q83AZ6, HEM6_COXBU ;  Q479T3, HEM6_DECAR ;  Q54IA7, HEM6_DICDI ;
DR   Q9V3D2, HEM6_DROME ;  A7ZPN6, HEM6_ECO24 ;  B7UGD5, HEM6_ECO27 ;
DR   B7MHT7, HEM6_ECO45 ;  B7LCI0, HEM6_ECO55 ;  Q8XBI4, HEM6_ECO57 ;
DR   B5YZY1, HEM6_ECO5E ;  B7NPX2, HEM6_ECO7I ;  B7MY86, HEM6_ECO81 ;
DR   B7M6U5, HEM6_ECO8A ;  C4ZX09, HEM6_ECOBW ;  B1XAA7, HEM6_ECODH ;
DR   A8A2T4, HEM6_ECOHS ;  A1ADV0, HEM6_ECOK1 ;  Q0TF33, HEM6_ECOL5 ;
DR   Q8FFA3, HEM6_ECOL6 ;  B1IWM6, HEM6_ECOLC ;  P36553, HEM6_ECOLI ;
DR   B7N626, HEM6_ECOLU ;  B6I512, HEM6_ECOSE ;  B1LMN0, HEM6_ECOSM ;
DR   A4WD41, HEM6_ENT38 ;  A7MKX5, HEM6_ENTS8 ;  Q6D8U8, HEM6_ERWCT ;
DR   B2VI13, HEM6_ERWT9 ;  B7LKJ9, HEM6_ESCF3 ;  B0U151, HEM6_FRAP2 ;
DR   Q14HF0, HEM6_FRAT1 ;  A7NC51, HEM6_FRATF ;  Q2A3H9, HEM6_FRATH ;
DR   B2SGG9, HEM6_FRATM ;  A0Q6H6, HEM6_FRATN ;  Q0BLZ2, HEM6_FRATO ;
DR   Q5NFZ8, HEM6_FRATT ;  A4IY09, HEM6_FRATW ;  Q7NEK3, HEM6_GLOVI ;
DR   Q42840, HEM6_HORVU ;  P36551, HEM6_HUMAN ;  Q5QXJ4, HEM6_IDILO ;
DR   B5XVR1, HEM6_KLEP3 ;  A6TC68, HEM6_KLEP7 ;  Q5X5U7, HEM6_LEGPA ;
DR   A5IBB3, HEM6_LEGPC ;  Q5ZW72, HEM6_LEGPH ;  Q5WX75, HEM6_LEGPL ;
DR   P84155, HEM6_LEIMA ;  Q11GB4, HEM6_MESSB ;  Q603L4, HEM6_METCA ;
DR   Q1H4H0, HEM6_METFK ;  P36552, HEM6_MOUSE ;  Q0AEP6, HEM6_NITEC ;
DR   Q82TL0, HEM6_NITEU ;  A6WZC8, HEM6_OCHA4 ;  Q7XPL2, HEM6_ORYSJ ;
DR   C6D9M5, HEM6_PECCP ;  Q7N6Z9, HEM6_PHOLL ;  Q6LLK0, HEM6_PHOPR ;
DR   A1VN15, HEM6_POLNA ;  Q12C42, HEM6_POLSJ ;  A3PF71, HEM6_PROM0 ;
DR   A2C524, HEM6_PROM1 ;  A8G786, HEM6_PROM2 ;  A2BYW5, HEM6_PROM5 ;
DR   Q318G0, HEM6_PROM9 ;  Q7V9T7, HEM6_PROMA ;  B4EZS7, HEM6_PROMH ;
DR   Q7V568, HEM6_PROMM ;  Q7UZS3, HEM6_PROMP ;  A2BTG1, HEM6_PROMS ;
DR   Q46IN4, HEM6_PROMT ;  Q48QH6, HEM6_PSE14 ;  A6UX86, HEM6_PSEA7 ;
DR   B7V0Q9, HEM6_PSEA8 ;  Q02V57, HEM6_PSEAB ;  P43898, HEM6_PSEAE ;
DR   Q1I2G6, HEM6_PSEE4 ;  Q4KKQ4, HEM6_PSEF5 ;  C3K4I0, HEM6_PSEFS ;
DR   A4XNB8, HEM6_PSEMY ;  A5VWK4, HEM6_PSEP1 ;  Q3KKE0, HEM6_PSEPF ;
DR   B0KF35, HEM6_PSEPG ;  Q88RQ6, HEM6_PSEPK ;  B1J4A2, HEM6_PSEPW ;
DR   Q88B49, HEM6_PSESM ;  Q500S4, HEM6_PSEU2 ;  A4VFI3, HEM6_PSEU5 ;
DR   B2U8Z4, HEM6_RALPJ ;  Q8XXC3, HEM6_RALSO ;  Q3B7D0, HEM6_RAT   ;
DR   B3PV29, HEM6_RHIE6 ;  Q2K5S3, HEM6_RHIEC ;  Q1MDJ5, HEM6_RHIL3 ;
DR   B5ZY73, HEM6_RHILW ;  Q92PD8, HEM6_RHIME ;  C3PM25, HEM6_RICAE ;
DR   A8GQB7, HEM6_RICAH ;  A8GY81, HEM6_RICB8 ;  Q1RGQ3, HEM6_RICBR ;
DR   Q92FV8, HEM6_RICCN ;  Q4UJP2, HEM6_RICFE ;  Q9ZC86, HEM6_RICPR ;
DR   C4K2Y8, HEM6_RICPU ;  B0BVQ3, HEM6_RICRO ;  A8GU63, HEM6_RICRS ;
DR   Q68VN1, HEM6_RICTY ;  Q21PU0, HEM6_SACD2 ;  B5F0I0, HEM6_SALA4 ;
DR   A9MID0, HEM6_SALAR ;  Q57LQ6, HEM6_SALCH ;  B5FQE4, HEM6_SALDC ;
DR   B5R4G0, HEM6_SALEP ;  B5RCS3, HEM6_SALG2 ;  B4TCI1, HEM6_SALHS ;
DR   B4T0I0, HEM6_SALNS ;  Q5PI28, HEM6_SALPA ;  A9N336, HEM6_SALPB ;
DR   C0PZ88, HEM6_SALPC ;  B5BB50, HEM6_SALPK ;  B4TR28, HEM6_SALSV ;
DR   Q8Z4U8, HEM6_SALTI ;  P33771, HEM6_SALTY ;  Q9UTE2, HEM6_SCHPO ;
DR   A8GHH2, HEM6_SERP5 ;  A1S1K6, HEM6_SHEAM ;  B8E3K7, HEM6_SHEB2 ;
DR   A3CYL1, HEM6_SHEB5 ;  A6WHB7, HEM6_SHEB8 ;  Q12T99, HEM6_SHEDO ;
DR   B0TLD7, HEM6_SHEHH ;  Q8EKQ2, HEM6_SHEON ;  A8GYI0, HEM6_SHEPA ;
DR   A4Y1D3, HEM6_SHEPC ;  B8CHB9, HEM6_SHEPW ;  A0KR67, HEM6_SHESA ;
DR   A8FP82, HEM6_SHESH ;  Q0HPA0, HEM6_SHESM ;  Q0I0R6, HEM6_SHESR ;
DR   A1RDY8, HEM6_SHESW ;  B1KCX1, HEM6_SHEWM ;  B2TX24, HEM6_SHIB3 ;
DR   Q31Y44, HEM6_SHIBS ;  Q32DB7, HEM6_SHIDS ;  Q0T273, HEM6_SHIF8 ;
DR   Q83QN1, HEM6_SHIFL ;  Q3YZA7, HEM6_SHISS ;  A6U9R1, HEM6_SINMW ;
DR   Q2NS88, HEM6_SODGM ;  P35055, HEM6_SOYBN ;  B4SNL7, HEM6_STRM5 ;
DR   B2FND0, HEM6_STRMK ;  Q5N3S5, HEM6_SYNP6 ;  Q7U4M7, HEM6_SYNPX ;
DR   Q3AWA8, HEM6_SYNS9 ;  Q3AMK3, HEM6_SYNSC ;  P72848, HEM6_SYNY3 ;
DR   Q8DL15, HEM6_THEEB ;  B8GTF9, HEM6_THISH ;  Q42946, HEM6_TOBAC ;
DR   C5CLQ3, HEM6_VARPS ;  A5F4C4, HEM6_VIBC3 ;  Q9KVT4, HEM6_VIBCH ;
DR   C3LPC8, HEM6_VIBCM ;  A7N128, HEM6_VIBHB ;  Q87KE3, HEM6_VIBPA ;
DR   B7VMW3, HEM6_VIBSL ;  Q8DDD5, HEM6_VIBVU ;  Q7MGL4, HEM6_VIBVY ;
DR   Q8D1X2, HEM6_WIGBR ;  Q8PF76, HEM6_XANAC ;  Q3BMT4, HEM6_XANC5 ;
DR   Q4UP76, HEM6_XANC8 ;  B0RYP5, HEM6_XANCB ;  Q8P3Q0, HEM6_XANCP ;
DR   Q2NY70, HEM6_XANOM ;  B2SK75, HEM6_XANOP ;  Q5GUY0, HEM6_XANOR ;
DR   Q9PHC7, HEM6_XYLFA ;  B0U1G5, HEM6_XYLFM ;  Q87FB2, HEM6_XYLFT ;
DR   P11353, HEM6_YEAST ;  A1JL37, HEM6_YERE8 ;  A7FG82, HEM6_YERP3 ;
DR   Q1C5T7, HEM6_YERPA ;  B2K962, HEM6_YERPB ;  Q8ZCF9, HEM6_YERPE ;
DR   A9QZK6, HEM6_YERPG ;  Q1CJZ7, HEM6_YERPN ;  A4TMK2, HEM6_YERPP ;
DR   Q668I6, HEM6_YERPS ;  B1JSJ6, HEM6_YERPY ;
//
ID   1.3.3.4
DE   Protoporphyrinogen oxidase.
AN   Protoporphyrinogen IX oxidase.
AN   Protoporphyrinogenase.
CA   Protoporphyrinogen-IX + 3 O(2) = protoporphyrin-IX + 3 H(2)O(2).
CF   FAD.
CC   -!- Also slowly oxidizes mesoporphyrinogen IX.
DR   Q94IG7, PPOCM_SPIOL;  P55826, PPOC_ARATH ;  Q9AR38, PPOC_ORYSJ ;
DR   O24163, PPOC_TOBAC ;  O24164, PPOM_TOBAC ;  P32397, PPOX_BACSU ;
DR   P56602, PPOX_BOVIN ;  Q54DT8, PPOX_DICDI ;  P50336, PPOX_HUMAN ;
DR   Q60HD5, PPOX_MACFA ;  P51175, PPOX_MOUSE ;  P0A5A8, PPOX_MYCBO ;
DR   Q50008, PPOX_MYCLE ;  P0A5A7, PPOX_MYCTU ;  P56601, PPOX_MYXXA ;
DR   O32434, PPOX_PROFF ;  Q10062, PPOX_SCHPO ;  P40012, PPOX_YEAST ;
//
ID   1.3.3.5
DE   Bilirubin oxidase.
CA   2 bilirubin + O(2) = 2 biliverdin + 2 H(2)O.
DR   Q12737, BLRO_MYRVE ;
//
ID   1.3.3.6
DE   Acyl-CoA oxidase.
CA   Acyl-CoA + O(2) = trans-2,3-dehydroacyl-CoA + H(2)O(2).
CF   FAD.
CC   -!- Acts on CoA derivatives of fatty acids with chain length from C(8) to
CC       C(18).
DR   Q9ZQP2, ACO12_ARATH;  Q9LMI7, ACO32_ARATH;  O65202, ACOX1_ARATH;
DR   Q3SZP5, ACOX1_BOVIN;  Q9Z1N0, ACOX1_CAVPO;  Q54GQ6, ACOX1_DICDI;
DR   Q7KML2, ACOX1_DROME;  Q15067, ACOX1_HUMAN;  Q9R0H0, ACOX1_MOUSE;
DR   Q8HYL8, ACOX1_PHACI;  Q5RC19, ACOX1_PONAB;  P07872, ACOX1_RAT  ;
DR   O74934, ACOX1_YARLI;  O65201, ACOX2_ARATH;  Q00468, ACOX2_CANMA;
DR   P11356, ACOX2_CANTR;  O64894, ACOX2_CUCMA;  O74935, ACOX2_YARLI;
DR   P0CZ23, ACOX3_ARATH;  O15254, ACOX3_HUMAN;  Q9EPL9, ACOX3_MOUSE;
DR   Q5RAU0, ACOX3_PONAB;  Q63448, ACOX3_RAT  ;  O74936, ACOX3_YARLI;
DR   Q96329, ACOX4_ARATH;  P05335, ACOX4_CANMA;  P06598, ACOX4_CANTR;
DR   P08790, ACOX5_CANTR;  Q756A9, ACOX_ASHGO ;  P34355, ACOX_CAEEL ;
DR   Q6FY63, ACOX_CANGA ;  Q6BRD5, ACOX_DEBHA ;  Q6CKK7, ACOX_KLULA ;
DR   Q9Y7B1, ACOX_PICPA ;  P13711, ACOX_YEAST ;  P0CZ24, Y3669_ARATH;
//
ID   1.3.3.7
DE   Dihydrouracil oxidase.
CA   5,6-dihydrouracil + O(2) = uracil + H(2)O(2).
CF   FMN.
CC   -!- Also oxidizes dihydrothymine to thymine.
//
ID   1.3.3.8
DE   Tetrahydroberberine oxidase.
AN   THB oxidase.
CA   (S)-tetrahydroberberine + 2 O(2) = berberine + 2 H(2)O(2).
CF   Flavoprotein.
CC   -!- (R)-tetrahydroberberines are not oxidized.
CC   -!- Formerly EC 1.5.3.8.
//
ID   1.3.3.9
DE   Secologanin synthase.
CA   Loganin + NADPH + O(2) = secologanin + NADP(+) + 2 H(2)O.
CF   Heme-thiolate.
CC   -!- Secologanin is the precursor of the monoterpenoid indole alkaloids
CC       and ipecac alkaloids.
PR   PROSITE; PDOC00081;
DR   Q05047, C72A1_CATRO;
//
ID   1.3.3.10
DE   Tryptophan alpha,beta-oxidase.
AN   L-tryptophan 2',3'-oxidase.
AN   L-tryptophan alpha,beta-dehydrogenase.
CA   L-tryptophan + O(2) = alpha,beta-didehydrotryptophan + H(2)O(2).
CF   Heme.
CC   -!- The enzyme from Chromobacterium violaceum is specific for tryptophan
CC       derivatives possessing its carboxyl group free or as an amide or
CC       ester, and an unsubstituted indole ring.
CC   -!- Also catalyzes the alpha,beta dehydrogenation of L-tryptophan side
CC       chains in peptides.
CC   -!- The product of the reaction can hydrolyze spontaneously to form
CC       indolepyruvate.
CC   -!- Formerly EC 1.4.3.17.
//
ID   1.3.3.11
DE   Pyrroloquinoline-quinone synthase.
CA   6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-
CA   dicarboxylate + 3 O(2) = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-
CA   f]quinoline-2,7,9-tricarboxylate + 2 H(2)O(2) + 2 H(2)O.
CC   -!- So far only a single turnover of the enzyme has been observed,
CC       and the pyrroloquinoline quinone remains bound to it; it is not yet
CC       known what releases the product in the bacterium.
DR   Q49150, PQQCD_METEA;  Q6F9J1, PQQC_ACIAD ;  B7H2Y2, PQQC_ACIB3 ;
DR   B7I6M6, PQQC_ACIB5 ;  B2I0I3, PQQC_ACIBC ;  B0VQD5, PQQC_ACIBS ;
DR   B0V496, PQQC_ACIBY ;  P07780, PQQC_ACICA ;  A5FUM6, PQQC_ACICJ ;
DR   B9JJ30, PQQC_AGRRK ;  C1DEW7, PQQC_AZOVD ;  Q89FG3, PQQC_BRAJA ;
DR   A4YZY5, PQQC_BRASO ;  A7MN58, PQQC_ENTS8 ;  B2VL12, PQQC_ERWT9 ;
DR   Q9L3B2, PQQC_GLUOX ;  Q0BQS6, PQQC_GRABC ;  B5XX60, PQQC_KLEP3 ;
DR   A6T9H1, PQQC_KLEP7 ;  P27505, PQQC_KLEPN ;  Q50438, PQQC_METFL ;
DR   Q48CT5, PQQC_PSE14 ;  B7VAB8, PQQC_PSEA8 ;  Q02LD4, PQQC_PSEAB ;
DR   Q9I2C2, PQQC_PSEAE ;  Q1IG47, PQQC_PSEE4 ;  P55173, PQQC_PSEFL ;
DR   A4XTR2, PQQC_PSEMY ;  A5VXG6, PQQC_PSEP1 ;  B0KJ68, PQQC_PSEPG ;
DR   Q88QV6, PQQC_PSEPK ;  B1JDZ8, PQQC_PSEPW ;  Q88A82, PQQC_PSESM ;
DR   Q4ZMC3, PQQC_PSEU2 ;  Q9EXV0, PQQC_RHIME ;  Q6N8F5, PQQC_RHOPA ;
DR   B3QBT0, PQQC_RHOPT ;  A3PMI4, PQQC_RHOS1 ;  Q3IZR5, PQQC_RHOS4 ;
DR   A4WPI0, PQQC_RHOS5 ;  B9KMC3, PQQC_RHOSK ;  Q5LTB2, PQQC_SILPO ;
DR   Q8PHY3, PQQC_XANAC ;  Q3BQI6, PQQC_XANC5 ;  Q4UXI2, PQQC_XANC8 ;
DR   B0RQ27, PQQC_XANCB ;  Q8P6M9, PQQC_XANCP ;  Q2P4Y7, PQQC_XANOM ;
DR   B2SSW1, PQQC_XANOP ;  Q5H233, PQQC_XANOR ;
//
ID   1.3.3.12
DE   L-galactonolactone oxidase.
AN   L-xylono-1,4-lactone oxidase.
CA   L-galactono-1,4-lactone + O(2) = L-ascorbate + H(2)O(2).
CF   FAD.
CC   -!- Acts on the 1,4-lactones of L-galactonic, D-altronic, L-fuconic,
CC       D-arabinic and D-threonic acids.
CC   -!- Not identical with EC 1.1.3.8 (cf. EC 1.3.2.3).
CC   -!- Formerly EC 1.1.3.24.
//
ID   1.3.5.1
DE   Succinate dehydrogenase (ubiquinone).
AN   Succinic dehydrogenase.
CA   Succinate + ubiquinone = fumarate + ubiquinol.
CF   FAD; Iron-sulfur.
CC   -!- The complex, present in mitochondria, can be degraded to form
CC       EC 1.3.99.1, which no longer reacts with ubiquinone.
PR   PROSITE; PDOC00393;
DR   O82663, DHSA1_ARATH;  Q9ZPX5, DHSA2_ARATH;  Q6PA58, DHSAA_XENLA;
DR   Q801S2, DHSAB_XENLA;  P31039, DHSA_BOVIN ;  Q09508, DHSA_CAEEL ;
DR   Q9YHT1, DHSA_CHICK ;  Q7ZVF3, DHSA_DANRE ;  Q9U3X4, DHSA_DICDI ;
DR   Q94523, DHSA_DROME ;  P31040, DHSA_HUMAN ;  Q8HXW3, DHSA_MACFA ;
DR   Q0QF17, DHSA_MESAU ;  Q8K2B3, DHSA_MOUSE ;  Q6ZDY8, DHSA_ORYSJ ;
DR   Q0QF01, DHSA_PIG   ;  Q5R616, DHSA_PONAB ;  Q920L2, DHSA_RAT   ;
DR   Q9UTJ7, DHSA_SCHPO ;  Q28ED0, DHSA_XENTR ;  Q00711, DHSA_YEAST ;
DR   Q8LBZ7, DHSB1_ARATH;  Q8LB02, DHSB2_ARATH;  Q9FJP9, DHSB3_ARATH;
DR   Q75CI4, DHSB_ASHGO ;  Q3T189, DHSB_BOVIN ;  A8WPF0, DHSB_CAEBR ;
DR   Q09545, DHSB_CAEEL ;  Q6FWS8, DHSB_CANGA ;  Q9YHT2, DHSB_CHICK ;
DR   P48932, DHSB_CHOCR ;  P48933, DHSB_CYACA ;  A5PL98, DHSB_DANRE ;
DR   Q55CC2, DHSB_DICDI ;  P21914, DHSB_DROME ;  P21912, DHSB_HUMAN ;
DR   Q9CQA3, DHSB_MOUSE ;  O42772, DHSB_MYCGR ;  Q007T0, DHSB_PIG   ;
DR   P80477, DHSB_PORPU ;  P21913, DHSB_RAT   ;  P80480, DHSB_RECAM ;
DR   P21911, DHSB_SCHPO ;  Q70KF8, DHSB_UROFA ;  P32420, DHSB_USTMA ;
DR   Q3B8J8, DHSB_XENLA ;  B0BM36, DHSB_XENTR ;  P21801, DHSB_YEAST ;
DR   P47052, DHSX_YEAST ;
//
ID   1.3.5.2
DE   Dihydroorotate dehydrogenase (quinone).
AN   DHOD.
AN   DHOdehase.
AN   DHODH.
CA   (S)-dihydroorotate + a quinone = orotate + a quinol.
CF   FMN.
CC   -!- This Class 2 dihydroorotate dehydrogenase enzyme contains FMN.
CC   -!- The enzyme is found in eukaryotes in the mitochondrial membrane,
CC       and in some Gram negative bacteria associated with the cytoplasmic
CC       membrane.
CC   -!- The reaction is the only redox reaction in the de-novo biosynthesis
CC       of pyrimidine nucleotides.
CC   -!- The best quinone electron acceptors for the enzyme from bovine liver
CC       are ubiquinone-6 and ubiquinone-7, although simple quinones, such as
CC       benzoquinone, can also act as acceptor at lower rates.
CC   -!- Methyl-, ethyl-, tert-butyl and benzyl-(S)-dihydroorotates are also
CC       substrates, but 1- and 3-methyl and 1,3-dimethyl methyl-(S)-
CC       dihydroorotates are not.
CC   -!- Class 1 dihydroorotate dehydrogenases use either fumarate
CC       (EC 1.3.98.1), NAD(+) (EC 1.3.1.14) or NADP(+) (EC 1.3.1.15) as
CC       electron acceptor.
CC   -!- Formerly EC 1.3.99.11.
PR   PROSITE; PDOC00708;
DR   Q6CTX8, PYRD2_KLULA;  Q6SZS6, PYRD2_KLUMA;  B0CA74, PYRD_ACAM1 ;
DR   A1TPZ2, PYRD_ACIAC ;  Q6FCL9, PYRD_ACIAD ;  B7GZW7, PYRD_ACIB3 ;
DR   B7I2L5, PYRD_ACIB5 ;  B2HUT6, PYRD_ACIBC ;  B0VKB8, PYRD_ACIBS ;
DR   A3M6Y2, PYRD_ACIBT ;  B0V824, PYRD_ACIBY ;  B9MIU2, PYRD_ACIET ;
DR   B7J5Q1, PYRD_ACIF2 ;  B5EL46, PYRD_ACIF5 ;  A1W7S6, PYRD_ACISJ ;
DR   A3N0D6, PYRD_ACTP2 ;  B3H1B5, PYRD_ACTP7 ;  B0BP55, PYRD_ACTPJ ;
DR   A6VP48, PYRD_ACTSZ ;  A0KKK9, PYRD_AERHH ;  A4SME2, PYRD_AERS4 ;
DR   P28294, PYRD_AGRAE ;  B9J901, PYRD_AGRRK ;  A9CK85, PYRD_AGRT5 ;
DR   B9JR03, PYRD_AGRVS ;  B2UNA2, PYRD_AKKM8 ;  Q0A8M5, PYRD_ALHEH ;
DR   B6ELD1, PYRD_ALISL ;  B8JDF0, PYRD_ANAD2 ;  Q2IQI6, PYRD_ANADE ;
DR   A7HD76, PYRD_ANADF ;  B4UG99, PYRD_ANASK ;  Q3MDU0, PYRD_ANAVT ;
DR   P32746, PYRD_ARATH ;  Q5P1A9, PYRD_AROAE ;  B8H8Q4, PYRD_ARTCA ;
DR   A0JX31, PYRD_ARTS2 ;  Q75CE1, PYRD_ASHGO ;  A8HZX8, PYRD_AZOC5 ;
DR   A1K7M2, PYRD_AZOSB ;  C1DDY1, PYRD_AZOVD ;  A1URL3, PYRD_BARBK ;
DR   Q6G4F7, PYRD_BARHE ;  Q6G159, PYRD_BARQU ;  A9IQ81, PYRD_BART1 ;
DR   Q1LT62, PYRD_BAUCH ;  Q2KW44, PYRD_BORA1 ;  Q7WGE4, PYRD_BORBR ;
DR   Q7W4W6, PYRD_BORPA ;  A9I8M0, PYRD_BORPD ;  Q7VTR9, PYRD_BORPE ;
DR   Q5E9W3, PYRD_BOVIN ;  Q89VA7, PYRD_BRAJA ;  A5EA61, PYRD_BRASB ;
DR   A4Z2G7, PYRD_BRASO ;  B2S953, PYRD_BRUA1 ;  Q2YPG3, PYRD_BRUA2 ;
DR   Q57F47, PYRD_BRUAB ;  A9M7Z9, PYRD_BRUC2 ;  C0RH28, PYRD_BRUMB ;
DR   Q8YFB1, PYRD_BRUME ;  A5VNQ1, PYRD_BRUO2 ;  B0CJU0, PYRD_BRUSI ;
DR   Q8G2K8, PYRD_BRUSU ;  P57443, PYRD_BUCAI ;  Q8K9I5, PYRD_BUCAP ;
DR   Q1BWM4, PYRD_BURCA ;  A0K729, PYRD_BURCH ;  B4E8N4, PYRD_BURCJ ;
DR   Q0BFR0, PYRD_BURCM ;  A9AJX4, PYRD_BURM1 ;  A3MJ98, PYRD_BURM7 ;
DR   A2S374, PYRD_BURM9 ;  Q62K45, PYRD_BURMA ;  A1V4A5, PYRD_BURMS ;
DR   A3NUS1, PYRD_BURP0 ;  Q3JSS8, PYRD_BURP1 ;  A3N925, PYRD_BURP6 ;
DR   B2JKL9, PYRD_BURP8 ;  Q63TV1, PYRD_BURPS ;  Q39GX5, PYRD_BURS3 ;
DR   Q2SVL9, PYRD_BURTA ;  Q13ZM3, PYRD_BURXL ;  Q874I4, PYRD_CANAL ;
DR   Q6SZS5, PYRD_CANGA ;  B3PIL8, PYRD_CELJU ;  A9WDI1, PYRD_CHLAA ;
DR   B9LHC1, PYRD_CHLSY ;  Q7NX17, PYRD_CHRVO ;  A8AID4, PYRD_CITK8 ;
DR   A5CS38, PYRD_CLAM3 ;  B0RIK6, PYRD_CLAMS ;  Q480K7, PYRD_COLP3 ;
DR   Q6NH79, PYRD_CORDI ;  Q8FTC6, PYRD_COREF ;  A4QEA4, PYRD_CORGB ;
DR   Q8NQC0, PYRD_CORGL ;  Q9FB59, PYRD_CORST ;  B6J754, PYRD_COXB1 ;
DR   B6J0A5, PYRD_COXB2 ;  A9KCF2, PYRD_COXBN ;  A9NCV1, PYRD_COXBR ;
DR   Q83CY0, PYRD_COXBU ;  Q0KBT4, PYRD_CUPNH ;  Q472J6, PYRD_CUPPJ ;
DR   B3R4T0, PYRD_CUPTR ;  B1WUM4, PYRD_CYAA5 ;  B8HW33, PYRD_CYAP4 ;
DR   B7KIU7, PYRD_CYAP7 ;  B7JXU8, PYRD_CYAP8 ;  Q47GW1, PYRD_DECAR ;
DR   C1CX89, PYRD_DEIDV ;  Q1J132, PYRD_DEIGD ;  Q9RX14, PYRD_DEIRA ;
DR   A9BWU2, PYRD_DELAS ;  A5EV79, PYRD_DICNV ;  P32748, PYRD_DROME ;
DR   A7ZK49, PYRD_ECO24 ;  B7UN24, PYRD_ECO27 ;  B7MHP7, PYRD_ECO45 ;
DR   B7LE45, PYRD_ECO55 ;  P0A7E2, PYRD_ECO57 ;  B5YT76, PYRD_ECO5E ;
DR   B7NM29, PYRD_ECO7I ;  B7MS56, PYRD_ECO81 ;  B7M874, PYRD_ECO8A ;
DR   C4ZQ71, PYRD_ECOBW ;  B1X8P9, PYRD_ECODH ;  A7ZYP7, PYRD_ECOHS ;
DR   A1A9L5, PYRD_ECOK1 ;  Q0TJB6, PYRD_ECOL5 ;  Q8FJ91, PYRD_ECOL6 ;
DR   B1IVY7, PYRD_ECOLC ;  P0A7E1, PYRD_ECOLI ;  B7N3A7, PYRD_ECOLU ;
DR   B6I919, PYRD_ECOSE ;  B1LJR7, PYRD_ECOSM ;  Q1RDR9, PYRD_ECOUT ;
DR   C5BD71, PYRD_EDWI9 ;  A4W8V7, PYRD_ENT38 ;  A7MEW0, PYRD_ENTS8 ;
DR   Q6D456, PYRD_ERWCT ;  B2VC84, PYRD_ERWT9 ;  Q2N6N6, PYRD_ERYLH ;
DR   B7LNV5, PYRD_ESCF3 ;  A5FHT2, PYRD_FLAJ1 ;  Q9F1U7, PYRD_FLALU ;
DR   A6H0L5, PYRD_FLAPJ ;  Q7NC99, PYRD_GLOVI ;  A0M4D0, PYRD_GRAFK ;
DR   Q7VL56, PYRD_HAEDU ;  Q4QKB5, PYRD_HAEI8 ;  A5UC11, PYRD_HAEIE ;
DR   A5UEP8, PYRD_HAEIG ;  P45477, PYRD_HAEIN ;  B8F848, PYRD_HAEPS ;
DR   Q2SCG9, PYRD_HAHCH ;  A1WTJ3, PYRD_HALHL ;  Q5UYF1, PYRD_HALMA ;
DR   B0R808, PYRD_HALS3 ;  Q9HMK2, PYRD_HALSA ;  C4K4A3, PYRD_HAMD5 ;
DR   Q17WU9, PYRD_HELAH ;  B6JL11, PYRD_HELP2 ;  B5Z6I2, PYRD_HELPG ;
DR   Q1CU70, PYRD_HELPH ;  Q9ZM11, PYRD_HELPJ ;  B2USR9, PYRD_HELPS ;
DR   O25655, PYRD_HELPY ;  A4G7T7, PYRD_HERAR ;  Q02127, PYRD_HUMAN ;
DR   Q5QX65, PYRD_IDILO ;  A6T106, PYRD_JANMA ;  A6WD43, PYRD_KINRD ;
DR   B5XY59, PYRD_KLEP3 ;  A6T739, PYRD_KLEP7 ;  B2GHT4, PYRD_KOCRD ;
DR   Q5X496, PYRD_LEGPA ;  A5ICX8, PYRD_LEGPC ;  Q5ZUH7, PYRD_LEGPH ;
DR   Q5WVN0, PYRD_LEGPL ;  Q6AE78, PYRD_LEIXX ;  B1Y3C1, PYRD_LEPCP ;
DR   Q65TR8, PYRD_MANSM ;  A1TZG0, PYRD_MARAV ;  A6VW35, PYRD_MARMS ;
DR   Q11M76, PYRD_MESSB ;  B7KZJ5, PYRD_METC4 ;  Q609J2, PYRD_METCA ;
DR   Q1H411, PYRD_METFK ;  B3DX48, PYRD_METI4 ;  B8ID11, PYRD_METNO ;
DR   A2SHQ5, PYRD_METPP ;  O35435, PYRD_MOUSE ;  B1MPD4, PYRD_MYCA9 ;
DR   P65909, PYRD_MYCBO ;  A1KKI2, PYRD_MYCBP ;  C1AQ55, PYRD_MYCBT ;
DR   A4TB97, PYRD_MYCGI ;  P46727, PYRD_MYCLE ;  B2HFZ1, PYRD_MYCMM ;
DR   Q73YS2, PYRD_MYCPA ;  A0QZY9, PYRD_MYCS2 ;  A3Q1C6, PYRD_MYCSJ ;
DR   A1UHW0, PYRD_MYCSK ;  Q1B765, PYRD_MYCSS ;  A5U4G5, PYRD_MYCTA ;
DR   P65908, PYRD_MYCTU ;  A0PQW5, PYRD_MYCUA ;  A1TAT2, PYRD_MYCVP ;
DR   Q1D7Y6, PYRD_MYXXD ;  Q3IU78, PYRD_NATPD ;  B9L9P6, PYRD_NAUPA ;
DR   Q5F605, PYRD_NEIG1 ;  A9M3G1, PYRD_NEIM0 ;  Q9JX66, PYRD_NEIMA ;
DR   Q9K1D7, PYRD_NEIMB ;  A1KRQ4, PYRD_NEIMF ;  Q0AIB4, PYRD_NITEC ;
DR   Q82ST3, PYRD_NITEU ;  Q2Y5H8, PYRD_NITMU ;  A6Q2V6, PYRD_NITSB ;
DR   Q5YVM8, PYRD_NOCFA ;  A1SJF2, PYRD_NOCSJ ;  B2IU79, PYRD_NOSP7 ;
DR   Q8YPC6, PYRD_NOSS1 ;  Q2GBY1, PYRD_NOVAD ;  A6WVY1, PYRD_OCHA4 ;
DR   A7HQ77, PYRD_PARL1 ;  P57858, PYRD_PASMU ;  C6DFC0, PYRD_PECCP ;
DR   Q7N617, PYRD_PHOLL ;  Q6LRA2, PYRD_PHOPR ;  Q08210, PYRD_PLAF7 ;
DR   A1VQJ1, PYRD_POLNA ;  B1XV77, PYRD_POLNS ;  Q129L9, PYRD_POLSJ ;
DR   A4SWU5, PYRD_POLSQ ;  Q5R6X6, PYRD_PONAB ;  B4EVC3, PYRD_PROMH ;
DR   Q7V473, PYRD_PROMM ;  Q48JY0, PYRD_PSE14 ;  Q15UB7, PYRD_PSEA6 ;
DR   A6V325, PYRD_PSEA7 ;  B7UWL8, PYRD_PSEA8 ;  Q02PL5, PYRD_PSEAB ;
DR   Q9HZF8, PYRD_PSEAE ;  Q1ICL4, PYRD_PSEE4 ;  Q4KFI7, PYRD_PSEF5 ;
DR   C3K017, PYRD_PSEFS ;  Q3IGZ1, PYRD_PSEHT ;  A4XWQ0, PYRD_PSEMY ;
DR   Q3KFC7, PYRD_PSEPF ;  B0KG90, PYRD_PSEPG ;  Q88L40, PYRD_PSEPK ;
DR   B1J5B5, PYRD_PSEPW ;  Q883P1, PYRD_PSESM ;  Q4ZUM3, PYRD_PSEU2 ;
DR   A4VM41, PYRD_PSEU5 ;  Q4FS74, PYRD_PSYA2 ;  Q1QBS1, PYRD_PSYCK ;
DR   A1SX25, PYRD_PSYIN ;  A5WDZ3, PYRD_PSYWF ;  Q1LP27, PYRD_RALME ;
DR   Q8XYY7, PYRD_RALSO ;  Q63707, PYRD_RAT   ;  B3PNN8, PYRD_RHIE6 ;
DR   Q2KCS8, PYRD_RHIEC ;  Q1MLT8, PYRD_RHIL3 ;  Q98B89, PYRD_RHILO ;
DR   B5ZPH6, PYRD_RHILW ;  Q92S77, PYRD_RHIME ;  C3MFT0, PYRD_RHISN ;
DR   C0ZZY4, PYRD_RHOE4 ;  Q21WC4, PYRD_RHOFD ;  C1ASU1, PYRD_RHOOB ;
DR   Q2IR55, PYRD_RHOP2 ;  Q07TQ6, PYRD_RHOP5 ;  Q6NBN1, PYRD_RHOPA ;
DR   Q13D13, PYRD_RHOPS ;  B3QEE3, PYRD_RHOPT ;  Q2RX27, PYRD_RHORT ;
DR   A3PN03, PYRD_RHOS1 ;  Q3IZ94, PYRD_RHOS4 ;  B9KNA2, PYRD_RHOSK ;
DR   A7NLW9, PYRD_ROSCS ;  A5UX75, PYRD_ROSS1 ;  Q21JW9, PYRD_SACD2 ;
DR   Q6V3W9, PYRD_SACKL ;  B5F1U2, PYRD_SALA4 ;  A8LY18, PYRD_SALAI ;
DR   A9MHU3, PYRD_SALAR ;  Q57QU4, PYRD_SALCH ;  B5FQY8, PYRD_SALDC ;
DR   B5QZE8, PYRD_SALEP ;  B5R8M3, PYRD_SALG2 ;  B4TDY5, PYRD_SALHS ;
DR   B4T1Y8, PYRD_SALNS ;  Q5PGE0, PYRD_SALPA ;  A9N6Y4, PYRD_SALPB ;
DR   C0PVS5, PYRD_SALPC ;  B5BBM2, PYRD_SALPK ;  B4TRW8, PYRD_SALSV ;
DR   Q8Z7S9, PYRD_SALTI ;  A4X619, PYRD_SALTO ;  P25468, PYRD_SALTY ;
DR   P32747, PYRD_SCHPO ;  A8GCK4, PYRD_SERP5 ;  A1S5Z4, PYRD_SHEAM ;
DR   B8E984, PYRD_SHEB2 ;  A3D5B9, PYRD_SHEB5 ;  A6WP30, PYRD_SHEB8 ;
DR   A9L4D0, PYRD_SHEB9 ;  Q12NG2, PYRD_SHEDO ;  Q081J9, PYRD_SHEFN ;
DR   B0TIY0, PYRD_SHEHH ;  A3QDX8, PYRD_SHELP ;  Q8EDZ8, PYRD_SHEON ;
DR   A8H3X8, PYRD_SHEPA ;  A4Y7I2, PYRD_SHEPC ;  B8CPG0, PYRD_SHEPW ;
DR   A0KW50, PYRD_SHESA ;  A8FW61, PYRD_SHESH ;  Q0HJL0, PYRD_SHESM ;
DR   Q0HVV6, PYRD_SHESR ;  A1RJ06, PYRD_SHESW ;  B1KDM8, PYRD_SHEWM ;
DR   B2TUD4, PYRD_SHIB3 ;  Q31YK8, PYRD_SHIBS ;  Q32HW1, PYRD_SHIDS ;
DR   Q0T689, PYRD_SHIF8 ;  Q83RX6, PYRD_SHIFL ;  Q3Z3H6, PYRD_SHISS ;
DR   A6U5U0, PYRD_SINMW ;  Q2NU82, PYRD_SODGM ;  Q1GVC1, PYRD_SPHAL ;
DR   Q827Q6, PYRD_STRAW ;  Q9KXR7, PYRD_STRCO ;  B1W464, PYRD_STRGG ;
DR   B4STK4, PYRD_STRM5 ;  B2FPI7, PYRD_STRMK ;  Q30R79, PYRD_SULDN ;
DR   A6Q8G0, PYRD_SULNB ;  Q31RJ7, PYRD_SYNE7 ;  Q2JRL7, PYRD_SYNJA ;
DR   Q2JJF3, PYRD_SYNJB ;  Q5N2Q8, PYRD_SYNP6 ;  Q7U3U2, PYRD_SYNPX ;
DR   P74782, PYRD_SYNY3 ;  C5BKZ2, PYRD_TERTT ;  Q8DLB7, PYRD_THEEB ;
DR   Q47RF2, PYRD_THEFY ;  Q72KU3, PYRD_THET2 ;  Q5SK69, PYRD_THET8 ;
DR   Q3SL21, PYRD_THIDA ;  Q113R9, PYRD_TRIEI ;  A1WJ81, PYRD_VEREI ;
DR   A5F839, PYRD_VIBC3 ;  Q9KRZ2, PYRD_VIBCH ;  C3LMH4, PYRD_VIBCM ;
DR   Q5E5B6, PYRD_VIBF1 ;  B5FE17, PYRD_VIBFM ;  A7N0L2, PYRD_VIBHB ;
DR   Q87PB7, PYRD_VIBPA ;  B7VNK9, PYRD_VIBSL ;  Q8D9G5, PYRD_VIBVU ;
DR   Q7MKX3, PYRD_VIBVY ;  Q8D370, PYRD_WIGBR ;  Q8PLJ2, PYRD_XANAC ;
DR   Q3BUJ7, PYRD_XANC5 ;  Q4UTX5, PYRD_XANC8 ;  B0RTS3, PYRD_XANCB ;
DR   Q8P9R0, PYRD_XANCP ;  Q2P3M0, PYRD_XANOM ;  B2SLB9, PYRD_XANOP ;
DR   Q5H0N0, PYRD_XANOR ;  A7IBC2, PYRD_XANP2 ;  B2I9T5, PYRD_XYLF2 ;
DR   Q9PAE7, PYRD_XYLFA ;  B0U5I1, PYRD_XYLFM ;  Q87A77, PYRD_XYLFT ;
DR   A1JMP8, PYRD_YERE8 ;  A7FJU2, PYRD_YERP3 ;  Q1CA44, PYRD_YERPA ;
DR   B2JYR8, PYRD_YERPB ;  Q8ZG91, PYRD_YERPE ;  A9R7L2, PYRD_YERPG ;
DR   Q1CGJ0, PYRD_YERPN ;  A4TMZ3, PYRD_YERPP ;  Q66CG4, PYRD_YERPS ;
DR   B1JQS0, PYRD_YERPY ;
//
ID   1.3.5.3
DE   Protoporphyrinogen IX dehydrogenase (menaquinone).
CA   Protoporphyrinogen IX + 3 menaquinone = protoporphyrin IX + 3 menaquinol.
CC   -!- This enzyme enables Escherichia coli to synthesize heme in both
CC       aerobic and anaerobic environments.
DR   P0ACB6, HEMG_ECO57 ;  P0ACB5, HEMG_ECOL6 ;  P0ACB4, HEMG_ECOLI ;
DR   Q9L6L1, HEMG_SALTY ;
//
ID   1.3.5.4
DE   Fumarate reductase (menaquinone).
AN   Succinate dehydrogenase (menaquinone).
CA   Succinate + a menaquinone = fumarate + a menaquinol.
CC   -!- The reaction is catalyzed in the opposite direction.
CC   -!- The enzyme is part of the anaerobic electron transfer chain of
CC       certain bacteria.
CC   -!- It allows fumarate to serve as a terminal electron acceptor.
CC   -!- The enzyme from Escherichia coli contains a catalytic domain and an
CC       anchor domain, each consisting of two subunits.
CC   -!- One of the subunits of the catalytic domain contains a covalently-
CC       bound FAD cofactor and the fumarate binding site, and the other
CC       contains 3 iron-sulfur clusters.
CC   -!- The anchor domain interacts with the menaquinone.
CC   -!- The enzyme is closely related to EC 1.3.5.1 (succinate dehydrogenase
CC       (ubiquinone)).
//
ID   1.3.5.5
DE   15-cis-phytoene desaturase.
AN   PDS.
AN   Phytoene desaturase.
AN   Plant-type phytoene desaturase.
CA   15-cis-phytoene + 2 plastoquinone = 9,15,9'-tri-cis-zeta-carotene +
CA   2 plastoquinol.
CC   -!- This enzyme is involved in carotenoid biosynthesis in plants and
CC       cyanobacteria.
CC   -!- The enzyme from Synechococcus can also use NAD(+) and NADP(+) as
CC       electron acceptor under anaerobic conditions.
CC   -!- The enzyme from Gentiana lutea shows no activity with NAD(+) or
CC       NADP(+).
//
ID   1.3.7.1
DE   6-hydroxynicotinate reductase.
AN   6-hydroxynicotinic reductase.
AN   6-oxotetrahydro-nicotinate dehydrogenase.
AN   HNA reductase.
CA   6-oxo-1,4,5,6-tetrahydronicotinate + oxidized ferredoxin =
CA   6-hydroxynicotinate + reduced ferredoxin.
CC   -!- Forms part of the nicotinate-fermentation catabolism pathway in
CC       Eubacterium barkeri.
CC   -!- Other enzymes involved in this pathway are EC 1.17.5.1, EC 3.5.2.18,
CC       EC 1.1.1.291, EC 5.4.99.4, EC 5.3.3.6, EC 4.2.1.85 and EC 4.1.3.32.
DR   Q0QLF7, HNR_EUBBA  ;
//
ID   1.3.7.2
DE   15,16-dihydrobiliverdin:ferredoxin oxidoreductase.
CA   15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IX-alpha +
CA   reduced ferredoxin.
CC   -!- Catalyzes the two-electron reduction of biliverdin IX-alpha at the
CC       C15 methine bridge.
CC   -!- It has been proposed that this enzyme and EC 1.3.7.3 function as a
CC       dual enzyme complex in the conversion of biliverdin IX-alpha into
CC       phycoerythrobilin.
DR   Q7NL66, PEBA_GLOVI ;  Q93TL6, PEBA_NOSP7 ;  A3PF83, PEBA_PROM0 ;
DR   A2C539, PEBA_PROM1 ;  A8G798, PEBA_PROM2 ;  A2CBW8, PEBA_PROM3 ;
DR   A9BCT3, PEBA_PROM4 ;  A2BYX6, PEBA_PROM5 ;  Q318E9, PEBA_PROM9 ;
DR   Q9K4U6, PEBA_PROMA ;  Q7V586, PEBA_PROMM ;  Q93SN8, PEBA_PROMP ;
DR   A2BTH4, PEBA_PROMS ;  Q46IM0, PEBA_PROMT ;  A5GIZ3, PEBA_SYNPW ;
DR   Q7U4P7, PEBA_SYNPX ;  Q02189, PEBA_SYNPY ;  Q3AUU5, PEBA_SYNS9 ;
DR   Q3AMI3, PEBA_SYNSC ;
//
ID   1.3.7.3
DE   Phycoerythrobilin:ferredoxin oxidoreductase.
CA   (3Z)-phycoerythrobilin + oxidized ferredoxin = 15,16-dihydrobiliverdin +
CA   reduced ferredoxin.
CC   -!- Catalyzes the two-electron reduction of the C2 and C3(1) diene system
CC       of 15,16-dihydrobiliverdin.
CC   -!- Specific for 15,16-dihydrobiliverdin.
CC   -!- It has been proposed that this enzyme and EC 1.3.7.2 function as a
CC       dual enzyme complex in the conversion of biliverdin IX-alpha into
CC       phycoerythrobilin.
DR   Q7NL65, PEBB_GLOVI ;  Q93TM8, PEBB_NOSP7 ;  A3PF82, PEBB_PROM0 ;
DR   A2C538, PEBB_PROM1 ;  A8G797, PEBB_PROM2 ;  A2CBW9, PEBB_PROM3 ;
DR   A9BCT2, PEBB_PROM4 ;  A2BYX5, PEBB_PROM5 ;  Q318F0, PEBB_PROM9 ;
DR   Q9K4U5, PEBB_PROMA ;  Q7V585, PEBB_PROMM ;  Q93SN7, PEBB_PROMP ;
DR   A2BTH3, PEBB_PROMS ;  Q46IM1, PEBB_PROMT ;  Q7U4P6, PEBB_SYNPX ;
DR   Q02190, PEBB_SYNPY ;  A5GVQ6, PEBB_SYNR3 ;  Q0ICV5, PEBB_SYNS3 ;
DR   Q3AUU4, PEBB_SYNS9 ;  Q10UW6, PEBB_TRIEI ;
//
ID   1.3.7.4
DE   Phytochromobilin:ferredoxin oxidoreductase.
AN   P-Phi-B synthase.
AN   PFB synthase.
AN   Phytochromobilin synthase.
CA   (3Z)-phytochromobilin + oxidized ferredoxin = biliverdin IX-alpha +
CA   reduced ferredoxin.
CC   -!- Catalyzes the two-electron reduction of biliverdin IX-alpha.
CC   -!- Can use 2Fe-2S ferredoxins from a number of sources as acceptor but
CC       not the 4Fe-4S ferredoxin from Clostridium pasteurianum.
CC   -!- The isomerization of (3Z)-phytochromobilin to (3E)-phytochromobilin
CC       is thought to occur prior to covalent attachment to apophytochrome in
CC       the plant cell cytoplasm.
CC   -!- Flavodoxins can be used instead of ferredoxin.
DR   Q9SR43, PFBS_ARATH ;
//
ID   1.3.7.5
DE   Phycocyanobilin:ferredoxin oxidoreductase.
CA   (3Z)-phycocyanobilin + oxidized ferredoxin = biliverdin IX-alpha +
CA   reduced ferredoxin.
CC   -!- Catalyzes the four-electron reduction of biliverdin IX-alpha
CC       (2-electron reduction at both the A and D rings).
CC   -!- Reaction proceeds via an isolatable 2-electron intermediate,
CC       18(1),18(2)-dihydrobiliverdin.
CC   -!- Flavodoxins can be used instead of ferredoxin.
CC   -!- The direct conversion of biliverdin IX-alpha (BV) to (3Z)-
CC       phycocyanobilin (PCB) in the cyanobacteria Synechocystis sp.
CC       PCC 6803, Anabaena sp. PCC7120 and Nostoc punctiforme is in contrast
CC       to the proposed pathways of PCB biosynthesis in the red alga
CC       Cyanidium caldarium, which involves (3Z)-phycoerythrobilin (PEB) as
CC       an intermediate and in the green alga Mesotaenium caldariorum,
CC       in which PCB is an isolable intermediate.
DR   Q3M745, PCYA_ANAVT ;  B1X018, PCYA_CYAA5 ;  B7KJQ2, PCYA_CYAP7 ;
DR   B7JWS2, PCYA_CYAP8 ;  Q7NHE8, PCYA_GLOVI ;  B0JPG5, PCYA_MICAN ;
DR   Q93TM9, PCYA_NOSP7 ;  Q93TN0, PCYA_NOSS1 ;  A3PCF5, PCYA_PROM0 ;
DR   A8G4C5, PCYA_PROM2 ;  A2CA92, PCYA_PROM3 ;  A2BW83, PCYA_PROM5 ;
DR   Q31BD0, PCYA_PROM9 ;  Q7VCC2, PCYA_PROMA ;  Q7V7Y8, PCYA_PROMM ;
DR   Q93TL5, PCYA_PROMP ;  A2BQN3, PCYA_PROMS ;  Q8KPS9, PCYA_SYNE7 ;
DR   Q5N5A3, PCYA_SYNP6 ;  Q7U7A1, PCYA_SYNPX ;  Q3AXI3, PCYA_SYNS9 ;
DR   Q3AKB1, PCYA_SYNSC ;  Q55891, PCYA_SYNY3 ;  P59288, PCYA_THEEB ;
DR   Q10X61, PCYA_TRIEI ;
//
ID   1.3.7.6
DE   Phycoerythrobilin synthase.
CA   (3Z)-phycoerythrobilin + 2 oxidized ferredoxin = biliverdin IX-alpha +
CA   2 reduced ferredoxin.
CC   -!- This enzyme, from a cyanophage infecting oceanic cyanobacteria of the
CC       Prochlorococcus genus, uses a four-electron reduction to carry out
CC       the reactions catalyzed by EC 1.3.7.2 and EC 1.3.7.3.
CC   -!- 15,16-dihydrobiliverdin is formed as a bound intermediate.
CC   -!- Free 15,16-dihydrobiliverdin can also act as a substrate to form
CC       phycoerythrobilin.
DR   Q58MU6, PEBS_BPPRM ;
//
ID   1.3.7.7
DE   Ferredoxin:protochlorophyllide reductase (ATP-dependent).
AN   Light-independent protochlorophyllide reductase.
CA   Chlorophyllide a + reduced ferredoxin + 2 ATP = protochlorophyllide +
CA   oxidized ferredoxin + 2 ADP + 2 phosphate.
CF   Iron-sulfur.
CC   -!- Occurs in photosynthetic bacteria, cyanobacteria, green algae and
CC       gymnosperms.
CC   -!- The enzyme catalyzes trans-reduction of the D-ring of
CC       protochlorophyllide; the product has the (7S,8S)-configuration.
CC   -!- Unlike EC 1.3.1.33 light is not required.
CC   -!- The enzyme contains a [4Fe-4S] cluster, and structurally resembles
CC       the Fe protein/MoFe protein complex of EC 1.18.6.1, which catalyzes
CC       an ATP-driven reduction.
//
ID   1.3.7.8
DE   Benzoyl-CoA reductase.
CA   Cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP +
CA   2 phosphate = benzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H(2)O.
CF   Iron-sulfur; Magnesium or manganese.
CC   -!- Inactive toward aromatic acids that are not CoA esters but will also
CC       catalyze the reaction: NH(3) + acceptor + 2 ADP + 2 phosphate + H(2)O
CC       = hydroxylamine + reduced acceptor + 2 ATP.
CC   -!- In the presence of reduced acceptor, but in the absence of oxidizable
CC       substrate, the enzyme catalyzes the hydrolysis of ATP to ADP plus
CC       phosphate.
CC   -!- Formerly EC 1.3.99.15.
DR   O87876, BCRA_THAAR ;  O87875, BCRB_THAAR ;  O87874, BCRC_THAAR ;
DR   O87877, BCRD_THAAR ;
//
ID   1.3.7.9
DE   4-hydroxybenzoyl-CoA reductase.
CA   Benzoyl-CoA + oxidized ferredoxin = 4-hydroxybenzoyl-CoA +
CA   reduced ferredoxin.
CF   Flavin; Iron-sulfur; Molybdenum.
CC   -!- Involved in the anaerobic pathway of phenol metabolism in bacteria.
CC   -!- A ferredoxin with two [4Fe-4S] clusters functions as the natural
CC       electron donor.
CC   -!- Formerly EC 1.3.99.20.
DR   O33819, HCRA_THAAR ;  O33820, HCRB_THAAR ;  O33818, HCRC_THAAR ;
//
ID   1.3.8.1
DE   Butyryl-CoA dehydrogenase.
AN   Butyryl dehydrogenase.
AN   Short-chain-acyl-CoA dehydrogenase.
AN   Unsaturated acyl-CoA reductase.
CA   Butanoyl-CoA + electron-transfer flavoprotein = 2-butenoyl-CoA + reduced
CA   electron-transfer flavoprotein.
CF   FAD.
CC   -!- The enzyme catalyzes the oxidation of saturated acyl-CoA thioesters
CC       to give a 2,3-unsaturated product by removal of the two pro-R-
CC       hydrogen atoms.
CC   -!- Formerly EC 1.3.2.1 and EC 1.3.99.2.
PR   PROSITE; PDOC00070;
DR   Q3ZBF6, ACADS_BOVIN;  P16219, ACADS_HUMAN;  Q07417, ACADS_MOUSE;
DR   P79273, ACADS_PIG  ;  Q5RAS0, ACADS_PONAB;  P15651, ACADS_RAT  ;
DR   P52042, ACDS_CLOAB ;  Q06319, ACDS_MEGEL ;
//
ID   1.3.98.1
DE   Dihydroorotate oxidase (fumarate).
AN   DHOD.
AN   DHODase.
AN   DHOdehase.
AN   Dihydoorotic acid dehydrogenase.
AN   Dihydroorotate dehydrogenase.
AN   Dihydroorotate oxidase.
CA   (S)-dihydroorotate + fumarate = orotate + succinate.
CF   FMN.
CC   -!- The reaction, which takes place in the cytosol, is the only redox
CC       reaction in the de novo biosynthesis of pyrimidine nucleotides.
CC   -!- Molecular oxygen can replace fumarate in vitro.
CC   -!- Other class 1 dihydroorotate dehydrogenases use either NAD(+)
CC       (EC 1.3.1.14) or NADP(+) (EC 1.3.1.15) as electron acceptor.
CC   -!- The membrane bound class 2 dihydroorotate dehydrogenase (EC 1.3.5.2)
CC       uses quinone as electron acceptor.
CC   -!- Formerly EC 1.3.3.1.
PR   PROSITE; PDOC00708;
DR   Q7Z895, PYRD1_KLULA;  Q7Z892, PYRD1_SACKL;  Q9YFI6, PYRDA_AERPE;
DR   O66461, PYRDA_AQUAE;  P59626, PYRDA_ENTFA;  Q5FJB5, PYRDA_LACAC;
DR   Q038Z3, PYRDA_LACC3;  Q1G864, PYRDA_LACDA;  Q047M3, PYRDA_LACDB;
DR   A8YVZ9, PYRDA_LACH4;  Q74J29, PYRDA_LACJO;  Q9CFC9, PYRDA_LACLA;
DR   Q53ZE5, PYRDA_LACLC;  A2RJT9, PYRDA_LACLM;  P77887, PYRDA_LACPL;
DR   A5VHS3, PYRDA_LACRD;  B2G5A3, PYRDA_LACRJ;  Q03HA9, PYRDA_PEDPA;
DR   Q01YA2, PYRDA_SOLUE;  Q3K2G4, PYRDA_STRA1;  Q8E6L0, PYRDA_STRA3;
DR   Q8E155, PYRDA_STRA5;  C0M8R7, PYRDA_STRE4;  Q99Z28, PYRDA_STRP1;
DR   P0DD66, PYRDA_STRP3;  Q8P0C0, PYRDA_STRP8;  A2RDV3, PYRDA_STRPG;
DR   Q9X9S0, PYRDA_STRPN;  P0DD67, PYRDA_STRPQ;  Q8DQG9, PYRDA_STRR6;
DR   C0MCW6, PYRDA_STRS7;  B9DUS7, PYRDA_STRU0;  B2V726, PYRDA_SULSY;
DR   Q7Z894, PYRD_SACBA ;  Q6V3X0, PYRD_SACCA ;  Q7Z893, PYRD_SACMI ;
DR   Q7Z891, PYRD_SACPA ;  Q57U83, PYRD_TRYB2 ;  Q4D3W2, PYRD_TRYCR ;
DR   P28272, PYRD_YEAST ;
//
ID   1.3.99.1
DE   Succinate dehydrogenase.
AN   Fumarate dehydrogenase.
AN   Fumarate reductase.
AN   Fumaric hydrogenase.
AN   Succinic dehydrogenase.
CA   Succinate + acceptor = fumarate + reduced acceptor.
CF   FAD.
PR   PROSITE; PDOC00393;
DR   P08065, DHSA_BACSU ;  P51054, DHSA_COXBU ;  P0AC43, DHSA_ECO57 ;
DR   P0AC42, DHSA_ECOL6 ;  P0AC41, DHSA_ECOLI ;  Q59661, DHSA_PARDE ;
DR   Q1RHB9, DHSA_RICBR ;  Q92J97, DHSA_RICCN ;  Q4UJM1, DHSA_RICFE ;
DR   P31038, DHSA_RICPR ;  Q68XN9, DHSA_RICTY ;  Q8ZQU3, DHSA_SALTY ;
DR   P08066, DHSB_BACSU ;  P51053, DHSB_COXBU ;  P07014, DHSB_ECOLI ;
DR   Q59662, DHSB_PARDE ;  Q1RGP3, DHSB_RICBR ;  Q92JJ8, DHSB_RICCN ;
DR   Q4UN71, DHSB_RICFE ;  Q9ZEA1, DHSB_RICPR ;  Q68XS0, DHSB_RICTY ;
DR   Q8ZQU2, DHSB_SALTY ;  Q9Z4P0, FRD2_SHEFN ;  P00363, FRDA_ECOLI ;
DR   P44894, FRDA_HAEIN ;  Q9ZMP0, FRDA_HELPJ ;  O06913, FRDA_HELPY ;
DR   P64175, FRDA_MYCBO ;  P64174, FRDA_MYCTU ;  P20922, FRDA_PROVU ;
DR   Q07WU7, FRDA_SHEFN ;  P0C278, FRDA_SHEFR ;  P83223, FRDA_SHEON ;
DR   P17412, FRDA_WOLSU ;  P0AC49, FRDB_ECO57 ;  P0AC48, FRDB_ECOL6 ;
DR   P0AC47, FRDB_ECOLI ;  P44893, FRDB_HAEIN ;  Q9ZMP1, FRDB_HELPJ ;
DR   O06914, FRDB_HELPY ;  Q10761, FRDB_MYCTU ;  P20921, FRDB_PROVU ;
DR   P0AC50, FRDB_SHIFL ;  P17596, FRDB_WOLSU ;
//
ID   1.3.99.2
DE   Transferred entry: 1.3.8.1.
//
ID   1.3.99.3
DE   Acyl-CoA dehydrogenase.
AN   Acyl dehydrogenase.
AN   Medium-chain acyl-CoA dehydrogenase.
CA   Acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor.
CF   FAD.
CC   -!- Forms with another flavoprotein ('electron-transferring
CC       flavoprotein') and EC 1.5.5.1 a system reducing ubiquinone and other
CC       acceptors.
CC   -!- Formerly EC 1.3.2.2.
PR   PROSITE; PDOC00070;
DR   A8XNF0, ACAD1_CAEBR;  A8WP91, ACAD2_CAEBR;  Q3SZB4, ACADM_BOVIN;
DR   Q22347, ACADM_CAEEL;  Q9VSA3, ACADM_DROME;  P11310, ACADM_HUMAN;
DR   Q8HXY8, ACADM_MACFA;  P45952, ACADM_MOUSE;  A5A6I0, ACADM_PANTR;
DR   P41367, ACADM_PIG  ;  P08503, ACADM_RAT  ;
//
ID   1.3.99.4
DE   3-oxosteroid 1-dehydrogenase.
CA   A 3-oxosteroid + acceptor = a 3-oxo-Delta(1)-steroid + reduced acceptor.
DR   P71864, 3O1D1_MYCTU;  Q7D5C1, 3O1D2_MYCTU;  Q06401, 3O1D_COMTE ;
DR   A0R4S9, 3O1D_MYCS2 ;  Q04616, 3O1D_RHOOP ;
//
ID   1.3.99.5
DE   3-oxo-5-alpha-steroid 4-dehydrogenase.
AN   Steroid 5-alpha-reductase.
CA   A 3-oxo-5-alpha-steroid + acceptor = a 3-oxo-Delta(4)-steroid + reduced
CA   acceptor.
DR   D2HBV9, PORED_AILME;  Q5RIU9, PORED_DANRE;  Q9H8P0, PORED_HUMAN;
DR   C7T2J9, PORED_MESAU;  Q9WUP4, PORED_MOUSE;  Q5RJM1, PORED_RAT  ;
DR   Q8AVI9, PORED_XENLA;  Q0P4J9, PORED_XENTR;  A5PJS2, S5A1_BOVIN ;
DR   P18405, S5A1_HUMAN ;  Q28891, S5A1_MACFA ;  Q68FF9, S5A1_MOUSE ;
DR   P24008, S5A1_RAT   ;  P31213, S5A2_HUMAN ;  Q28892, S5A2_MACFA ;
DR   Q99N99, S5A2_MOUSE ;  O18765, S5A2_PIG   ;  P31214, S5A2_RAT   ;
//
ID   1.3.99.6
DE   3-oxo-5-beta-steroid 4-dehydrogenase.
AN   Delta(4)-3-ketosteroid 5-beta-reductase.
CA   A 3-oxo-5-beta-steroid + acceptor = a 3-oxo-Delta(4)-steroid + reduced
CA   acceptor.
PR   PROSITE; PDOC00061;
//
ID   1.3.99.7
DE   Glutaryl-CoA dehydrogenase.
CA   Glutaryl-CoA + acceptor = crotonoyl-CoA + CO(2) + reduced acceptor.
CF   FAD.
PR   PROSITE; PDOC00070;
DR   Q2KHZ9, GCDH_BOVIN ;  Q20772, GCDH_CAEEL ;  Q54R47, GCDH_DICDI ;
DR   Q92947, GCDH_HUMAN ;  Q8HXX8, GCDH_MACFA ;  Q60759, GCDH_MOUSE ;
DR   P81140, GCDH_PIG   ;
//
ID   1.3.99.8
DE   2-furoyl-CoA dehydrogenase.
AN   Furoyl-CoA hydroxylase.
CA   2-furoyl-CoA + H(2)O + acceptor = S-(5-hydroxy-2-furoyl)-CoA + reduced
CA   acceptor.
CF   Copper.
CC   -!- The oxygen atom of the -OH produced is derived from water, not O(2).
CC   -!- The actual oxidative step is probably dehydrogenation of a hydrated
CC       form -CHOH-CH(2)- to -C(OH)=CH-, which tautomerizes non-enzymically
CC       to -CO-CH(2)-, giving (5-oxo-4,5-dihydro-2-furoyl)-CoA.
CC   -!- Methylene blue, nitro blue tetrazolium and a membrane fraction from
CC       Pseudomonas putida can act as acceptors.
//
ID   1.3.99.9
DE   Transferred entry: 1.21.99.1.
//
ID   1.3.99.10
DE   Isovaleryl-CoA dehydrogenase.
CA   3-methylbutanoyl-CoA + acceptor = 3-methylbut-2-enoyl-CoA + reduced
CA   acceptor.
CF   FAD.
CC   -!- Forms with another flavoprotein ('electron-transferring
CC       flavoprotein') and EC 1.5.5.1 a system reducing ubiquinone and other
CC       acceptors.
CC   -!- n-pentanoate can act as donor.
CC   -!- Not identical with EC 1.3.8.1, EC 1.3.99.3 or EC 1.3.99.12.
PR   PROSITE; PDOC00070;
DR   Q9FS88, IVD1_SOLTU ;  Q9FS87, IVD2_SOLTU ;  Q9SWG0, IVD_ARATH  ;
DR   Q3SZI8, IVD_BOVIN  ;  P34275, IVD_CAEEL  ;  P26440, IVD_HUMAN  ;
DR   Q9JHI5, IVD_MOUSE  ;  Q5RBD5, IVD_PONAB  ;  P12007, IVD_RAT    ;
//
ID   1.3.99.11
DE   Transferred entry: 1.3.5.2.
//
ID   1.3.99.12
DE   2-methylacyl-CoA dehydrogenase.
AN   Branched-chain acyl-CoA dehydrogenase.
CA   2-methylbutanoyl-CoA + acceptor = 2-methylbut-2-enoyl-CoA + reduced
CA   acceptor.
CF   FAD.
CC   -!- Also oxidizes 2-methylpropanoyl-CoA.
CC   -!- Not identical with EC 1.3.8.1, EC 1.3.99.3, EC 1.3.99.10 or
CC       EC 1.3.99.13.
PR   PROSITE; PDOC00070;
//
ID   1.3.99.13
DE   Long-chain-acyl-CoA dehydrogenase.
CA   Acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor.
CF   FAD.
CC   -!- Forms with another flavoprotein ('electron-transferring
CC       flavoprotein') and EC 1.5.5.1 a system reducing ubiquinone and other
CC       acceptors.
CC   -!- Not identical with EC 1.3.99.2, EC 1.3.99.3, EC 1.3.99.10 or
CC       EC 1.3.99.12.
PR   PROSITE; PDOC00070;
DR   P28330, ACADL_HUMAN;  Q60HI0, ACADL_MACFA;  P51174, ACADL_MOUSE;
DR   P79274, ACADL_PIG  ;  P15650, ACADL_RAT  ;
//
ID   1.3.99.14
DE   Cyclohexanone dehydrogenase.
CA   Cyclohexanone + acceptor = cyclohex-2-enone + reduced acceptor.
CC   -!- 2,6-dichloroindophenol can act as acceptor.
CC   -!- The corresponding ketones of cyclopentane and cycloheptane cannot act
CC       as donors.
//
ID   1.3.99.15
DE   Transferred entry: 1.3.7.8.
//
ID   1.3.99.16
DE   Isoquinoline 1-oxidoreductase.
CA   Isoquinoline + acceptor + H(2)O = isoquinolin-1(2H)-one + reduced
CA   acceptor.
CC   -!- The enzyme from Pseudomonas diminuta is specific toward N-containing
CC       N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol,
CC       phthalazine and quinazoline.
CC   -!- Electron acceptors include 1,2-benzoquinone, cytochrome c,
CC       ferricyanide, iodonitrotetrazolium chloride (INT), nitroblue
CC       tetrazolium (NBT), Meldola blue and phenazine methosulfate.
DR   Q51697, IORA_BREDI ;  Q51698, IORB_BREDI ;
//
ID   1.3.99.17
DE   Quinoline 2-oxidoreductase.
CA   Quinoline + acceptor + H(2)O = isoquinolin-1(2H)-one + reduced acceptor.
CF   FAD; Iron-sulfur; Molybdenum.
CC   -!- In addition to quinoline, quinolin-2-ol, quinolin-7-ol, quinolin-8-
CC       ol, 3-, 4- and 8-methylquinolines and 8-chloroquinoline are
CC       substrates.
CC   -!- Iodonitrotetrazolium chloride (INT) can act as an electron acceptor.
DR   P80464, Q2OA_COMTE ;  P80465, Q2OB_COMTE ;  P80466, Q2OG_COMTE ;
//
ID   1.3.99.18
DE   Quinaldate 4-oxidoreductase.
AN   Quinaldic acid 4-oxidoreductase.
CA   Quinaldate + acceptor + H(2)O = kynurenate + reduced acceptor.
CC   -!- The enzyme from Pseudomonas sp. AK2 also acts on quinoline-8-
CC       carboxylate, whereas that from Serratia marcescens 2CC-1 will oxidize
CC       nicotinate; quinaldate is a substrate for both of these enzymes.
CC   -!- 2,4,6-trinitrobenzene sulfonate acid, 1,4-benzoquinone, 1,2-
CC       naphthoquinone, nitroblue tetrazolium (NBT), thionine and menadione
CC       will serve as an electron acceptor for the former enzyme and
CC       ferricyanide for the latter; Meldola blue, iodonitrotetrazolium
CC       chloride (INT), phenazine methosulfate (PMS), 2,6-
CC       dichlorophenolindophenol (DCPIP) and cytochrome c will act as
CC       electron acceptors for both.
//
ID   1.3.99.19
DE   Quinoline-4-carboxylate 2-oxidoreductase.
AN   Quinaldic acid 4-oxidoreductase.
AN   Quinoline-4-carboxylic acid 2-oxidoreductase.
CA   Quinoline-4-carboxylate + acceptor + H(2)O = 2-oxo-1,2-dihydroquinoline-
CA   4-carboxylate + reduced acceptor.
CF   Flavin; Iron-sulfur; Molybdopterin cytosine dinucleotide.
CC   -!- Quinoline, 4-methylquinoline and 4-chloroquinoline can also serve as
CC       substrates for the enzyme from Agrobacterium sp. 1B.
CC   -!- Iodonitrotetrazolium chloride, thionine, menadione and 2,6-
CC       dichlorophenolindophenol can act as electron acceptors.
//
ID   1.3.99.20
DE   Transferred entry: 1.3.7.9.
//
ID   1.3.99.21
DE   (R)-benzylsuccinyl-CoA dehydrogenase.
CA   (R)-2-benzylsuccinyl-CoA + 2 electron-transferring flavoprotein = (E)-2-
CA   benzylidenesuccinyl-CoA + 2 reduced electron-transferring flavoprotein.
CF   FAD.
CC   -!- The enzyme is highly specific for (R)-benzylsuccinyl-CoA and is
CC       inhibited by (S)-benzylsuccinyl-CoA.
CC   -!- Forms the third step in the anaerobic toluene metabolic pathway in
CC       Thauera aromatica.
CC   -!- Uses the ferricenium ion as the preferred artificial electron
CC       acceptor.
CC   -!- Unlike other acyl-CoA dehydrogenases, this enzyme exhibits high
CC       substrate- and enantiomer specificity.
PR   PROSITE; PDOC00070;
DR   Q9KJE8, BBSG_THAAR ;
//
ID   1.3.99.22
DE   Coproporphyrinogen dehydrogenase.
AN   Coproporphyrinogen III oxidase.
AN   Oxygen-independent coproporphyrinogen-III oxidase.
AN   Radical SAM enzyme.
CA   Coproporphyrinogen-III + 2 S-adenosyl-L-methionine = protoporphyrinogen-
CA   IX + 2 CO(2) + 2 L-methionine + 2 5'-deoxyadenosine.
CF   Iron-sulfur.
CC   -!- Differs from EC 1.3.3.3 by using S-adenosyl-L-methionine (AdoMet)
CC       instead of oxygen as oxidant.
CC   -!- Occurs mainly in bacteria, whereas eukaryotes use the oxygen-
CC       dependent oxidase.
CC   -!- The reaction starts by using an electron from the reduced form of the
CC       enzyme's [4Fe-4S] cluster to split AdoMet into methionine and the
CC       radical 5'-deoxyadenosin-5'-yl; this radical initiates attack on the
CC       2-carboxyethyl groups, leading to their conversion into vinyl groups.
CC   -!- This conversion, -.CH-CH(2)-COO- -> -CH=CH(2) + CO(2) + e(-) replaces
CC       the electron initially used.
DR   P33770, HEMF_RHOS4 ;  O67886, HEMN_AQUAE ;  P54304, HEMN_BACSU ;
DR   O31381, HEMN_BRAJA ;  O34162, HEMN_CUPNH ;  P32131, HEMN_ECOLI ;
DR   Q9ZLH0, HEMN_HELPJ ;  O25376, HEMN_HELPY ;  P71756, HEMN_MYCTU ;
DR   Q51676, HEMN_PARDP ;  P95506, HEMN_PASHA ;  P77915, HEMN_PSEAE ;
DR   P95651, HEMN_RHOS5 ;  P0A1E2, HEMN_SALTI ;  P0A1E1, HEMN_SALTY ;
DR   P74132, HEMN_SYNY3 ;  O31067, HEMN_THEVL ;  Q796V8, HEMZ_BACSU ;
DR   P51008, HEMZ_RHOS4 ;
//
ID   1.3.99.23
DE   All-trans-retinol 13,14-reductase.
AN   (13,14)-all-trans-retinol saturase.
AN   All-trans-13,14-dihydroretinol:acceptor 13,14-oxidoreductase.
AN   Retinol saturase.
AN   RetSat.
CA   All-trans-13,14-dihydroretinol + acceptor = all-trans-retinol + reduced
CA   acceptor.
CC   -!- The reaction is only known to occur in the opposite direction to that
CC       given above, with the enzyme being specific for all-trans-retinol as
CC       substrate.
CC   -!- Neither all-trans-retinoic acid nor 9-cis, 11-cis or 13-cis-retinol
CC       isomers are substrates.
CC   -!- May play a role in the metabolism of vitamin A.
DR   Q5BLE8, RETST_DANRE;  Q6NUM9, RETST_HUMAN;  Q64FG0, RETST_MACFA;
DR   Q64FW2, RETST_MOUSE;  Q8VHE9, RETST_RAT  ;
//
ID   1.3.99.24
DE   2-amino-4-deoxychorismate dehydrogenase.
AN   2-amino-2-deoxyisochorismate dehydrogenase.
AN   ADIC dehydrogenase.
CA   (2S)-2-amino-4-deoxychorismate + FMN = 3-(1-carboxyvinyloxy)anthranilate
CA   + FMNH(2).
CC   -!- The sequential action of EC 2.6.1.86 and this enzyme leads to the
CC       formation of the benzoxazolinate moiety of the enediyne antitumor
CC       antibiotic C-1027.
//
ID   1.3.99.25
DE   Carvone reductase.
CA   (1) (+)-dihydrocarvone + acceptor = (-)-carvone + reduced acceptor.
CA   (2) (-)-isodihydrocarvone + acceptor = (+)-carvone + reduced acceptor.
CC   -!- Participates in the carveol and dihydrocarveol degradation pathway of
CC       the Gram-positive bacterium Rhodococcus erythropolis DCL14.
CC   -!- Has not been purified, and requires an unknown cofactor, which is
CC       different from NAD(+), NADP(+) or a flavin.
//
ID   1.3.99.n1
DE   3-hydroxybenzoyl-CoA reductase.
AN   3-hydroxybenzoyl-CoA reductase (dearomatising).
CA   3-hydroxybenzoyl-CoA + reduced acceptor + 2 ATP + 2 H(2)O =
CA   3-hydroxycyclohexa-1,5-diene-1-carbonyl-CoA + acceptor + 2 ADP +
CA   2 phosphate.
CF   Iron-sulfur; Magnesium or manganese.
CC   -!- Reduced methyl viologen can act as electron donor.
CC   -!- The enzyme also catalyzes the reaction of EC 1.3.7.8.
CC   -!- The reaction is catalyzed by a heterotetramer.
DR   O87876, BCRA_THAAR ;  O87875, BCRB_THAAR ;  O87874, BCRC_THAAR ;
DR   O87877, BCRD_THAAR ;
//
ID   1.3.99.n2
DE   2-iminoacetate synthase.
CA   2-iminoacetate + 4-cresol + 5'-deoxyadenosine + L-methionine + acceptor =
CA   L-tyrosine + S-adenosyl-L-methionine + reduced acceptor.
CC   -!- The reaction takes place in the reverse direction.
CC   -!- Binds a 4Fe-4S cluster.
CC   -!- The cluster is coordinated by 3 cysteines and an exchangeable SAM
CC       molecule.
CC   -!- The first stage of catalysis is reduction of the AdoMet to produce
CC       methionine and a 5-deoxyadenosin-5-yl radical that is crucial for the
CC       conversion of the substrate.
CC   -!- Part of the pathway for thiamine biosynthesis.
DR   P30140, THIH_ECOLI ;  Q9S498, THIH_SALTY ;
//
ID   1.4.1.1
DE   Alanine dehydrogenase.
CA   L-alanine + H(2)O + NAD(+) = pyruvate + NH(3) + NADH.
PR   PROSITE; PDOC00654;
DR   Q2FH00, DHA1_STAA3 ;  Q2FYJ2, DHA1_STAA8 ;  Q2YY66, DHA1_STAAB ;
DR   Q5HFY4, DHA1_STAAC ;  P63478, DHA1_STAAM ;  P99151, DHA1_STAAN ;
DR   Q6GGW9, DHA1_STAAR ;  Q6G9C3, DHA1_STAAS ;  Q8NWQ3, DHA1_STAAW ;
DR   Q2FG29, DHA2_STAA3 ;  Q2FXL7, DHA2_STAA8 ;  Q2YTD1, DHA2_STAAB ;
DR   Q5HF65, DHA2_STAAC ;  Q931P7, DHA2_STAAM ;  Q99TF4, DHA2_STAAN ;
DR   Q6GFZ8, DHA2_STAAR ;  Q6G8L8, DHA2_STAAS ;  Q8NW54, DHA2_STAAW ;
DR   Q08352, DHA_BACSU  ;  P17557, DHA_GEOSE  ;  P17556, DHA_LYSSH  ;
DR   P30234, DHA_MYCTU  ;  Q8CX61, DHA_OCEIH  ;  Q5HNJ6, DHA_STAEQ  ;
DR   Q8CNW8, DHA_STAES  ;  Q4L750, DHA_STAHJ  ;  Q49YD9, DHA_STAS1  ;
//
ID   1.4.1.2
DE   Glutamate dehydrogenase.
AN   Glutamic dehydrogenase.
CA   L-glutamate + H(2)O + NAD(+) = 2-oxoglutarate + NH(3) + NADH.
PR   PROSITE; PDOC00071;
DR   P41755, DHE2_ACHKL ;  P94316, DHE2_BACFR ;  P39633, DHE2_BACSU ;
DR   P27346, DHE2_CLODI ;  P24295, DHE2_CLOSY ;  P00365, DHE2_NEUCR ;
DR   P28997, DHE2_PEPAS ;  B2RKJ1, DHE2_PORG3 ;  P0C934, DHE2_PORGI ;
DR   Q9HZE0, DHE2_PSEAE ;  Q9USN5, DHE2_SCHPO ;  Q5HHC7, DHE2_STAAC ;
DR   Q99VD0, DHE2_STAAM ;  Q7A6H8, DHE2_STAAN ;  Q6GID0, DHE2_STAAR ;
DR   Q6GAW8, DHE2_STAAS ;  Q7A1B9, DHE2_STAAW ;  P20016, DHE2_THUTH ;
DR   P33327, DHE2_YEAST ;  P29051, DHE41_HALSI;  Q54VI3, GLUD2_DICDI;
DR   P50735, GUDB_BACSU ;
//
ID   1.4.1.3
DE   Glutamate dehydrogenase (NAD(P)(+)).
AN   Glutamic dehydrogenase.
CA   L-glutamate + H(2)O + NAD(P)(+) = 2-oxoglutarate + NH(3) + NAD(P)H.
PR   PROSITE; PDOC00071;
DR   Q43314, DHE1_ARATH ;  Q38946, DHE2_ARATH ;  P80053, DHE2_SULSO ;
DR   Q9YC65, DHE3_AERPE ;  Q9S7A0, DHE3_ARATH ;  P94598, DHE3_BACTN ;
DR   P00366, DHE3_BOVIN ;  P82264, DHE3_CHAAC ;  P00368, DHE3_CHICK ;
DR   Q54KB7, DHE3_DICDI ;  P54385, DHE3_DROME ;  P28270, DHE3_ELEEL ;
DR   P00367, DHE3_HUMAN ;  Q43260, DHE3_MAIZE ;  P26443, DHE3_MOUSE ;
DR   P42174, DHE3_PIG   ;  Q47950, DHE3_PYRAB ;  Q47951, DHE3_PYREN ;
DR   P80319, DHE3_PYRFU ;  P0CL73, DHE3_PYRHO ;  P0CL72, DHE3_PYRHR ;
DR   O59650, DHE3_PYRKO ;  Q09115, DHE3_PYRWO ;  P10860, DHE3_RAT   ;
DR   Q53199, DHE3_RHISN ;  P93541, DHE3_SOLLC ;  Q56304, DHE3_THELI ;
DR   P96110, DHE3_THEMA ;  O74024, DHE3_THEPR ;  P52596, DHE3_VITVI ;
DR   Q64I01, DHE4_GORGO ;  P49448, DHE4_HUMAN ;  Q64HZ9, DHE4_HYLLA ;
DR   Q64HZ8, DHE4_PANTR ;  Q64I00, DHE4_PONPY ;  P95544, DHE4_PRERU ;
DR   O04937, DHEA_NICPL ;  Q9LEC8, DHEB_NICPL ;
//
ID   1.4.1.4
DE   Glutamate dehydrogenase (NADP(+)).
AN   Glutamic dehydrogenase.
CA   L-glutamate + H(2)O + NADP(+) = 2-oxoglutarate + NH(3) + NADPH.
PR   PROSITE; PDOC00071;
DR   Q9HSM4, DHE42_HALSA;  P54387, DHE4_AGABI ;  O93934, DHE4_BOTFU ;
DR   P28998, DHE4_CHLSO ;  Q8RQP4, DHE4_COREF ;  P31026, DHE4_CORGL ;
DR   P00370, DHE4_ECOLI ;  P18819, DHE4_EMENI ;  P28724, DHE4_GIAIN ;
DR   Q96VJ7, DHE4_GIBFU ;  P43793, DHE4_HAEIN ;  Q96UJ9, DHE4_HEBCY ;
DR   Q9ZKD8, DHE4_HELPJ ;  P55990, DHE4_HELPY ;  P54388, DHE4_LACBS ;
DR   P00369, DHE4_NEUCR ;  Q9HGU4, DHE4_NEUIN ;  Q9HGU3, DHE4_NEUSI ;
DR   Q9URS1, DHE4_PENCH ;  Q9S1F9, DHE4_PSYT1 ;  Q8TFF6, DHE4_SACBA ;
DR   Q8Z6F6, DHE4_SALTI ;  P15111, DHE4_SALTY ;  P29507, DHE4_SCHOC ;
DR   P78804, DHE4_SCHPO ;  P39475, DHE4_SULSH ;  P54386, DHE4_SYNY3 ;
DR   Q9HFR6, DHE4_TUBBO ;  P14657, DHE4_UNKP  ;  P07262, DHE4_YEAST ;
DR   P39708, DHE5_YEAST ;
//
ID   1.4.1.5
DE   L-amino-acid dehydrogenase.
CA   An L-amino acid + H(2)O + NAD(+) = a 2-oxo acid + NH(3) + NADH.
CC   -!- Acts on aliphatic amino acids.
//
ID   1.4.1.6
DE   Transferred entry: 1.21.4.1.
//
ID   1.4.1.7
DE   Serine 2-dehydrogenase.
AN   L-serine:NAD oxidoreductase (deaminating).
AN   Serine dehydrogenase.
CA   L-serine + H(2)O + NAD(+) = 3-hydroxypyruvate + NH(3) + NADH.
//
ID   1.4.1.8
DE   Valine dehydrogenase (NADP(+)).
CA   L-valine + H(2)O + NADP(+) = 3-methyl-2-oxobutanoate + NH(3) + NADPH.
//
ID   1.4.1.9
DE   Leucine dehydrogenase.
AN   LeuDH.
CA   L-leucine + H(2)O + NAD(+) = 4-methyl-2-oxopentanoate + NH(3) + NADH.
CC   -!- Also acts on isoleucine, valine, norvaline and norleucine.
PR   PROSITE; PDOC00071;
DR   P0A393, DHLE_BACCE ;  P0A392, DHLE_BACCR ;  Q53560, DHLE_BACLI ;
DR   P54531, DHLE_BACSU ;  P13154, DHLE_GEOSE ;  Q60030, DHLE_THEIN ;
//
ID   1.4.1.10
DE   Glycine dehydrogenase.
CA   Glycine + H(2)O + NAD(+) = glyoxylate + NH(3) + NADH.
//
ID   1.4.1.11
DE   L-erythro-3,5-diaminohexanoate dehydrogenase.
CA   L-erythro-3,5-diaminohexanoate + H(2)O + NAD(+) = (S)-5-amino-3-
CA   oxohexanoate + NH(3) + NADH.
//
ID   1.4.1.12
DE   2,4-diaminopentanoate dehydrogenase.
CA   2,4-diaminopentanoate + H(2)O + NAD(P)(+) = 2-amino-4-oxopentanoate +
CA   NH(3) + NAD(P)H.
CC   -!- Also acts, more slowly, on 2,5-diaminohexanoate forming 2-amino-5-
CC       oxohexanoate, which then cyclizes non-enzymically to 1-pyrroline-2-
CC       methyl-5-carboxylate.
//
ID   1.4.1.13
DE   Glutamate synthase (NADPH).
AN   Glutamate (reduced nicotinamide adenine dinucleotide phosphate) synthase.
AN   Glutamate synthetase (NADP).
AN   Glutamine amide-2-oxoglutarate aminotransferase (oxidoreductase, NADP).
AN   Glutamine-ketoglutaric aminotransferase.
AN   GOGAT.
AN   L-glutamate synthase.
AN   L-glutamate synthetase.
AN   L-glutamine:2-oxoglutarate aminotransferase, NADPH oxidizing.
AN   NADPH-dependent glutamate synthase.
AN   NADPH-glutamate synthase.
CA   2 L-glutamate + NADP(+) = L-glutamine + 2-oxoglutarate + NADPH.
CF   FAD; FMN; Iron-sulfur.
CC   -!- Formerly EC 2.6.1.53.
PR   PROSITE; PDOC00406;
DR   Q9C102, GLT1_SCHPO ;  P39812, GLTA_BACSU ;  Q05755, GLTB_AZOBR ;
DR   O34399, GLTB_BACSU ;  P09831, GLTB_ECOLI ;  Q05756, GLTD_AZOBR ;
DR   P09832, GLTD_ECOLI ;  O08340, GLTD_RHOSH ;  Q58746, GLUS_METJA ;
//
ID   1.4.1.14
DE   Glutamate synthase (NADH).
AN   L-glutamate synthase.
AN   L-glutamate synthetase.
AN   NADH-dependent glutamate synthase.
AN   NADH-glutamate synthase.
CA   2 L-glutamate + NAD(+) = L-glutamine + 2-oxoglutarate + NADH.
CF   FMN.
PR   PROSITE; PDOC00406;
DR   Q03460, GLSN_MEDSA ;  Q0JKD0, GLT1_ORYSJ ;  Q12680, GLT1_YEAST ;
DR   Q0DG35, GLT2_ORYSJ ;  Q9LV03, GLUT1_ARATH;
//
ID   1.4.1.15
DE   Lysine dehydrogenase.
CA   L-lysine + NAD(+) = 1,2-didehydropiperidine-2-carboxylate + NH(3) + NADH.
//
ID   1.4.1.16
DE   Diaminopimelate dehydrogenase.
AN   Meso-diaminopimelate D-dehydrogenase.
CA   Meso-2,6-diaminoheptanedioate + H(2)O + NADP(+) = L-2-amino-6-
CA   oxoheptanedioate + NH(3) + NADPH.
DR   P04964, DDH_CORGL  ;
//
ID   1.4.1.17
DE   N-methylalanine dehydrogenase.
CA   N-methyl-L-alanine + H(2)O + NADP(+) = pyruvate + methylamine + NADPH.
//
ID   1.4.1.18
DE   Lysine 6-dehydrogenase.
AN   L-lysine 6-dehydrogenase.
AN   L-lysine epsilon-dehydrogenase.
AN   LysDH.
CA   L-lysine + NAD(+) = (S)-2,3,4,5-tetrahydropyridine-2-carboxylate + NADH +
CA   NH(3).
CC   -!- Highly specific for L-lysine as substrate, although (S)-
CC       (2-aminoethyl)-L-cysteine can act as a substrate, but more slowly.
CC   -!- While the enzyme from Agrobacterium tumefaciens can use only NAD(+),
CC       that from the thermophilic bacterium Geobacillus stearothermophilus
CC       can also use NADP(+), but more slowly.
PR   PROSITE; PDOC00068;
//
ID   1.4.1.19
DE   Tryptophan dehydrogenase.
AN   L-Trp-dehydrogenase.
AN   L-tryptophan dehydrogenase.
AN   TrpDH.
CA   L-tryptophan + NAD(P)(+) = (indol-3-yl)pyruvate + NH(3) + NAD(P)H.
CF   Calcium.
//
ID   1.4.1.20
DE   Phenylalanine dehydrogenase.
AN   L-phenylalanine dehydrogenase.
AN   PheDH.
CA   L-phenylalanine + H(2)O + NAD(+) = phenylpyruvate + NH(3) + NADH.
CC   -!- The enzymes from Bacillus badius and Sporosarcina ureae are highly
CC       specific for L-phenylalanine; that from Bacillus sphaericus also acts
CC       on L-tyrosine.
PR   PROSITE; PDOC00071;
DR   Q59224, DHPH_BACBA ;  P23307, DHPH_LYSSH ;  P97014, DHPH_SPOUR ;
DR   P22823, DHPH_THEIN ;
//
ID   1.4.1.21
DE   Aspartate dehydrogenase.
AN   NAD-dependent aspartate dehydrogenase.
AN   NADH(2)-dependent aspartate dehydrogenase.
AN   NADP(+)-dependent aspartate dehydrogenase.
CA   L-aspartate + H(2)O + NAD(P)(+) = oxaloacetate + NH(3) + NAD(P)H.
CC   -!- Catalyzes the first step in NAD biosynthesis from aspartate.
CC   -!- Strictly specific for L-aspartate as substrate.
CC   -!- Has a higher affinity for NAD(+) than NADP(+).
DR   Q7WQR6, ASPD1_BORBR;  Q7W1T9, ASPD1_BORPA;  Q7VS76, ASPD1_BORPE;
DR   Q7WLJ8, ASPD2_BORBR;  Q7W850, ASPD2_BORPA;  Q7VX83, ASPD2_BORPE;
DR   Q7WE57, ASPD3_BORBR;  Q6FDH0, ASPD_ACIAD ;  B7GY04, ASPD_ACIB3 ;
DR   B7I8C4, ASPD_ACIB5 ;  B2HVA8, ASPD_ACIBC ;  A3M394, ASPD_ACIBT ;
DR   B0V9I9, ASPD_ACIBY ;  O28440, ASPD_ARCFU ;  Q89FY1, ASPD_BRAJA ;
DR   A3MD35, ASPD_BURM7 ;  A2RXI5, ASPD_BURM9 ;  Q62BI3, ASPD_BURMA ;
DR   A1UVC0, ASPD_BURMS ;  A3P4L6, ASPD_BURP0 ;  Q3JFK2, ASPD_BURP1 ;
DR   A3NIZ0, ASPD_BURP6 ;  Q63LV9, ASPD_BURPS ;  Q397Y5, ASPD_BURS3 ;
DR   Q2T559, ASPD_BURTA ;  Q0K391, ASPD_CUPNH ;  B3R8S4, ASPD_CUPTR ;
DR   Q66I59, ASPD_DANRE ;  A6ND91, ASPD_HUMAN ;  A6UVA8, ASPD_META3 ;
DR   Q8TS47, ASPD_METAC ;  Q46BD6, ASPD_METBF ;  Q12VF1, ASPD_METBU ;
DR   Q2FSK9, ASPD_METHJ ;  Q58325, ASPD_METJA ;  Q8TZ45, ASPD_METKA ;
DR   A4FY69, ASPD_METM5 ;  A9A7M3, ASPD_METM6 ;  A6VK38, ASPD_METM7 ;
DR   Q8PV99, ASPD_METMA ;  Q6LZ92, ASPD_METMP ;  O27054, ASPD_METTH ;
DR   A6USM7, ASPD_METVS ;  Q9DCQ2, ASPD_MOUSE ;  A9A1F7, ASPD_NITMS ;
DR   A6X792, ASPD_OCHA4 ;  Q126F5, ASPD_POLSJ ;  Q9HYA4, ASPD_PSEAE ;
DR   Q1QBB6, ASPD_PSYCK ;  B2UJ42, ASPD_RALPJ ;  Q8XRV9, ASPD_RALSO ;
DR   Q5I0J9, ASPD_RAT   ;  A8GIW3, ASPD_SERP5 ;  Q5LPG8, ASPD_SILPO ;
DR   Q9X1X6, ASPD_THEMA ;  B1LB32, ASPD_THESQ ;  Q0W7E0, ASPD_UNCMA ;
DR   Q5FW48, ASPD_XENTR ;
//
ID   1.4.2.1
DE   Glycine dehydrogenase (cytochrome).
AN   Glycine-cytochrome c reductase.
CA   Glycine + H(2)O + 2 ferricytochrome c = glyoxylate + NH(3) +
CA   2 ferrocytochrome c + 2 H(+).
//
ID   1.4.3.1
DE   D-aspartate oxidase.
AN   Aspartic oxidase.
CA   D-aspartate + H(2)O + O(2) = oxaloacetate + NH(3) + H(2)O(2).
CF   FAD.
PR   PROSITE; PDOC00573;
DR   A8WXM1, OXDD1_CAEBR;  Q19564, OXDD1_CAEEL;  O45307, OXDD2_CAEEL;
DR   P31228, OXDD_BOVIN ;  Q556W1, OXDD_DICDI ;  Q99489, OXDD_HUMAN ;
DR   Q922Z0, OXDD_MOUSE ;  A3KCL7, OXDD_PIG   ;
//
ID   1.4.3.2
DE   L-amino-acid oxidase.
AN   Ophio-amino-acid oxidase.
CA   An L-amino acid + H(2)O + O(2) = a 2-oxo acid + NH(3) + H(2)O(2).
CF   FAD.
DR   P86535, OXLA1_DABRR;  P0DI90, OXLA2_DABRR;  P0DI85, OXLA8_AGKAC;
DR   P0CC16, OXLA_AGKCL ;  P81382, OXLA_AGKRH ;  Q6T627, OXLA_BITGA ;
DR   P0DI86, OXLA_BOTAL ;  P0CC17, OXLA_BOTAT ;  P0DI87, OXLA_BOTIN ;
DR   P0DI88, OXLA_BOTJA ;  Q6TGQ9, OXLA_BOTJR ;  P0DI89, OXLA_BOTLC ;
DR   P0CJ40, OXLA_BOTMA ;  Q6TGQ8, OXLA_BOTMO ;  B5AR80, OXLA_BOTPA ;
DR   P0C2D1, OXLA_BOTPI ;  A8QL52, OXLA_BUNFA ;  A8QL51, OXLA_BUNMU ;
DR   O93364, OXLA_CROAD ;  P56742, OXLA_CROAT ;  P0C2D2, OXLA_CRODC ;
DR   Q4F867, OXLA_DABRU ;  A6MFL0, OXLA_DEMVE ;  B5U6Y8, OXLA_ECHOC ;
DR   P0C2D3, OXLA_ERIMA ;  Q90W54, OXLA_GLOBL ;  Q6STF1, OXLA_GLOHA ;
DR   Q96RQ9, OXLA_HUMAN ;  P81375, OXLA_MACLB ;  O09046, OXLA_MOUSE ;
DR   O08615, OXLA_MUSSP ;  A8QL58, OXLA_NAJAT ;  P0C2D4, OXLA_NAJKA ;
DR   P0DI91, OXLA_NAJOX ;  P23623, OXLA_NEUCR ;  Q4JHE2, OXLA_NOTSC ;
DR   P81383, OXLA_OPHHA ;  Q4JHE3, OXLA_OXYSC ;  P0C2D5, OXLA_PROFL ;
DR   P0C2D6, OXLA_PROMU ;  Q4JHE1, OXLA_PSEAU ;  B0VXW0, OXLA_SISCA ;
DR   P0DI84, OXLA_VIPAA ;  P0C2D7, OXLA_VIPBB ;  Q6WP39, OXLA_VIRST ;
DR   Q54EW2, Y9130_DICDI;  O34363, YOBN_BACSU ;
//
ID   1.4.3.3
DE   D-amino-acid oxidase.
CA   A D-amino acid + H(2)O + O(2) = a 2-oxo acid + NH(3) + H(2)O(2).
CF   FAD.
CC   -!- Wide specificity for D-amino acids.
CC   -!- Also acts on glycine.
PR   PROSITE; PDOC00573;
DR   O07727, DAO_MYCTU  ;  A8XJ44, OXDA2_CAEBR;  Q95XG9, OXDA2_CAEEL;
DR   Q9Z1M5, OXDA_CAVPO ;  Q9Z302, OXDA_CRIGR ;  P24552, OXDA_FUSSO ;
DR   P14920, OXDA_HUMAN ;  A2V9Y8, OXDA_MACFA ;  P18894, OXDA_MOUSE ;
DR   P00371, OXDA_PIG   ;  P22942, OXDA_RABIT ;  O35078, OXDA_RAT   ;
DR   P80324, OXDA_RHOTO ;  Q9Y7N4, OXDA_SCHPO ;  Q99042, OXDA_TRIVR ;
//
ID   1.4.3.4
DE   Monoamine oxidase.
AN   Adrenaline oxidase.
AN   Amine oxidase.
AN   Amine oxidase (flavin-containing).
AN   Tyraminase.
AN   Tyramine oxidase.
CA   RCH(2)NHR' + H(2)O + O(2) = RCHO + R'NH(2) + H(2)O(2).
CF   FAD.
CC   -!- Catalyzes the oxidative deamination of neurotransmitters and biogenic
CC       amines.
CC   -!- Acts on primary amines, and also on some secondary and tertiary
CC       amines.
CC   -!- It differs from EC 1.4.3.21, as it can oxidize secondary and tertiary
CC       amines but not methylamine.
CC   -!- Inhibited by acetylenic compounds such as chlorgyline, 1-deprenyl and
CC       pargyline but, unlike EC 1.4.3.21 and EC 1.4.3.22, it is not
CC       inhibited by semicarbazide.
CC   -!- Formerly EC 1.4.3.9.
DR   P21398, AOFA_BOVIN ;  P58027, AOFA_CANFA ;  Q54IT3, AOFA_DICDI ;
DR   Q5NU32, AOFA_HORSE ;  P21397, AOFA_HUMAN ;  Q64133, AOFA_MOUSE ;
DR   Q6Q2J0, AOFA_PIG   ;  Q5RE60, AOFA_PONAB ;  P21396, AOFA_RAT   ;
DR   O18851, AOFA_SHEEP ;  P56560, AOFB_BOVIN ;  Q7YRB7, AOFB_CANFA ;
DR   P58028, AOFB_CAVPO ;  Q556K3, AOFB_DICDI ;  P27338, AOFB_HUMAN ;
DR   Q8BW75, AOFB_MOUSE ;  Q6PLK3, AOFB_PIG   ;  Q5RE98, AOFB_PONAB ;
DR   P19643, AOFB_RAT   ;  Q556K4, AOFC_DICDI ;  P46882, AOFN_ASPNG ;
DR   Q6NSN2, AOF_DANRE  ;  P49253, AOF_ONCMY  ;
//
ID   1.4.3.5
DE   Pyridoxal 5'-phosphate synthase.
AN   PMP oxidase.
AN   Pyridoxamine 5'-phosphate oxidase.
AN   Pyridoxamine phosphate oxidase.
AN   Pyridoxamine-phosphate oxidase.
AN   Pyridoxine (pyridoxamine) 5'-phosphate oxidase.
AN   Pyridoxine (pyridoxamine)phosphate oxidase.
CA   (1) Pyridoxamine 5'-phosphate + H(2)O + O(2) = pyridoxal 5'-phosphate +
CA   NH(3) + H(2)O(2).
CA   (2) Pyridoxine 5'-phosphate + O(2) = pyridoxal 5'-phosphate + H(2)O(2).
CF   FMN.
CC   -!- In Escherichia coli, the coenzyme pyridoxal 5'-phosphate is
CC       synthesized de novo by a pathway that involves EC 1.2.1.72,
CC       EC 1.1.1.290, EC 2.6.1.52, EC 1.1.1.262, EC 2.6.99.2 and EC 1.4.3.5.
PR   PROSITE; PDOC00815;
DR   Q9UTQ1, PDX3_SCHPO ;  P38075, PDX3_YEAST ;  Q8Y1C3, PDXH1_RALSO;
DR   Q31IR4, PDXH1_THICR;  Q8XS03, PDXH2_RALSO;  Q31E41, PDXH2_THICR;
DR   B0C079, PDXH_ACAM1 ;  A1TQY3, PDXH_ACIAC ;  Q6F718, PDXH_ACIAD ;
DR   B7ICC6, PDXH_ACIB5 ;  B2I1H7, PDXH_ACIBC ;  B0VNC8, PDXH_ACIBS ;
DR   A3M9W4, PDXH_ACIBT ;  B0V9C9, PDXH_ACIBY ;  A0LR32, PDXH_ACIC1 ;
DR   A5FWR6, PDXH_ACICJ ;  A1W7K9, PDXH_ACISJ ;  A3N3U7, PDXH_ACTP2 ;
DR   B3GZF5, PDXH_ACTP7 ;  B0BU37, PDXH_ACTPJ ;  A6VKX9, PDXH_ACTSZ ;
DR   A0KI46, PDXH_AERHH ;  A4SKR0, PDXH_AERS4 ;  B9JAN3, PDXH_AGRRK ;
DR   Q8UHC2, PDXH_AGRT5 ;  B9JSN3, PDXH_AGRVS ;  Q0VSU8, PDXH_ALCBS ;
DR   Q0A757, PDXH_ALHEH ;  B6EQ13, PDXH_ALISL ;  B4RVA4, PDXH_ALTMD ;
DR   Q2IHV2, PDXH_ANADE ;  Q5PBF2, PDXH_ANAMM ;  Q2GJ82, PDXH_ANAPZ ;
DR   Q3MFQ5, PDXH_ANAVT ;  A8EV17, PDXH_ARCB4 ;  A8HRJ3, PDXH_AZOC5 ;
DR   C1DEH4, PDXH_AZOVD ;  Q5LFJ5, PDXH_BACFN ;  Q64WC2, PDXH_BACFR ;
DR   Q8A7E7, PDXH_BACTN ;  A1URW0, PDXH_BARBK ;  Q6G4D7, PDXH_BARHE ;
DR   Q6G0E0, PDXH_BARQU ;  Q1LU04, PDXH_BAUCH ;  Q6MK45, PDXH_BDEBA ;
DR   Q7VR53, PDXH_BLOFL ;  Q492T8, PDXH_BLOPB ;  Q2KVR0, PDXH_BORA1 ;
DR   Q7WG77, PDXH_BORBR ;  Q7W4Q1, PDXH_BORPA ;  A9I847, PDXH_BORPD ;
DR   Q7VU72, PDXH_BORPE ;  Q89RY8, PDXH_BRAJA ;  A5EEN4, PDXH_BRASB ;
DR   A4YQ21, PDXH_BRASO ;  B2S9Q7, PDXH_BRUA1 ;  Q2YMD1, PDXH_BRUA2 ;
DR   Q57EU9, PDXH_BRUAB ;  A9M8J1, PDXH_BRUC2 ;  C0RHC3, PDXH_BRUMB ;
DR   Q8YFK3, PDXH_BRUME ;  A5VNZ1, PDXH_BRUO2 ;  B0CKA2, PDXH_BRUSI ;
DR   Q8G2A9, PDXH_BRUSU ;  B1YVG1, PDXH_BURA4 ;  Q1BU45, PDXH_BURCA ;
DR   B1JXH8, PDXH_BURCC ;  A0K9Z1, PDXH_BURCH ;  B4E9I1, PDXH_BURCJ ;
DR   Q0BCF1, PDXH_BURCM ;  A9AGI1, PDXH_BURM1 ;  A3MHF0, PDXH_BURM7 ;
DR   A2S933, PDXH_BURM9 ;  Q62M91, PDXH_BURMA ;  A1V1A2, PDXH_BURMS ;
DR   A3NS64, PDXH_BURP0 ;  Q3JVD0, PDXH_BURP1 ;  A3N6I1, PDXH_BURP6 ;
DR   B2JDT0, PDXH_BURP8 ;  B2SY78, PDXH_BURPP ;  Q63WN7, PDXH_BURPS ;
DR   Q39DH2, PDXH_BURS3 ;  Q2T0M6, PDXH_BURTA ;  A4JHA1, PDXH_BURVG ;
DR   Q13UP6, PDXH_BURXL ;  Q20939, PDXH_CAEEL ;  B8H292, PDXH_CAUCN ;
DR   Q9A9Q6, PDXH_CAUCR ;  Q1QWA6, PDXH_CHRSD ;  Q7P203, PDXH_CHRVO ;
DR   A8AH19, PDXH_CITK8 ;  Q487G8, PDXH_COLP3 ;  Q83D18, PDXH_COXBU ;
DR   Q0K7Z0, PDXH_CUPNH ;  Q474I9, PDXH_CUPPJ ;  B3R5Q8, PDXH_CUPTR ;
DR   B1WR90, PDXH_CYAA5 ;  B8HMK7, PDXH_CYAP4 ;  B7K9I2, PDXH_CYAP7 ;
DR   B7JZR4, PDXH_CYAP8 ;  Q11U72, PDXH_CYTH3 ;  C1D0Z0, PDXH_DEIDV ;
DR   Q1J188, PDXH_DEIGD ;  Q9RX20, PDXH_DEIRA ;  A5EXX0, PDXH_DICNV ;
DR   A7ZMA0, PDXH_ECO24 ;  B7URX9, PDXH_ECO27 ;  B7M9Z2, PDXH_ECO45 ;
DR   B7L5J1, PDXH_ECO55 ;  Q8X647, PDXH_ECO57 ;  B5Z472, PDXH_ECO5E ;
DR   B7NTZ4, PDXH_ECO7I ;  B7MVB6, PDXH_ECO81 ;  B7M0J5, PDXH_ECO8A ;
DR   C4ZYA1, PDXH_ECOBW ;  B1XFV0, PDXH_ECODH ;  A8A0I1, PDXH_ECOHS ;
DR   A1ABI3, PDXH_ECOK1 ;  Q0THJ0, PDXH_ECOL5 ;  Q8FH87, PDXH_ECOL6 ;
DR   B1IQB6, PDXH_ECOLC ;  P0AFI7, PDXH_ECOLI ;  B7NB92, PDXH_ECOLU ;
DR   B6IB77, PDXH_ECOSE ;  B1LEP8, PDXH_ECOSM ;  Q1RBF7, PDXH_ECOUT ;
DR   C5BE32, PDXH_EDWI9 ;  Q3YSS1, PDXH_EHRCJ ;  Q2GFR2, PDXH_EHRCR ;
DR   Q5FH81, PDXH_EHRRG ;  Q5HBZ2, PDXH_EHRRW ;  A4W9V9, PDXH_ENT38 ;
DR   A7MMK2, PDXH_ENTS8 ;  Q6D5V3, PDXH_ERWCT ;  B2VEN4, PDXH_ERWT9 ;
DR   Q2N6B2, PDXH_ERYLH ;  B7LQN2, PDXH_ESCF3 ;  A5FB76, PDXH_FLAJ1 ;
DR   A6H098, PDXH_FLAPJ ;  Q0RUF3, PDXH_FRAAA ;  Q2JGW9, PDXH_FRASC ;
DR   Q5FPH2, PDXH_GLUOX ;  Q0BVM8, PDXH_GRABC ;  A0M2G0, PDXH_GRAFK ;
DR   Q7VP83, PDXH_HAEDU ;  Q4QM38, PDXH_HAEI8 ;  P44909, PDXH_HAEIN ;
DR   Q2SDP4, PDXH_HAHCH ;  A1WXY4, PDXH_HALHL ;  A4G883, PDXH_HERAR ;
DR   Q0C3Z2, PDXH_HYPNA ;  Q5QTW7, PDXH_IDILO ;  A6T1X9, PDXH_JANMA ;
DR   Q28PH0, PDXH_JANSC ;  A6WE21, PDXH_KINRD ;  A6T9Y6, PDXH_KLEP7 ;
DR   Q5X7K4, PDXH_LEGPA ;  A5IH19, PDXH_LEGPC ;  Q5ZY37, PDXH_LEGPH ;
DR   Q5WZ02, PDXH_LEGPL ;  B0SGE9, PDXH_LEPBA ;  Q04R37, PDXH_LEPBJ ;
DR   Q04ZE7, PDXH_LEPBL ;  B0SPV0, PDXH_LEPBP ;  B1XYE2, PDXH_LEPCP ;
DR   Q72PF1, PDXH_LEPIC ;  Q8F6Y3, PDXH_LEPIN ;  Q2W8Y5, PDXH_MAGSA ;
DR   Q65QT9, PDXH_MANSM ;  A1TWZ3, PDXH_MARAV ;  Q0ARD7, PDXH_MARMM ;
DR   Q11KF1, PDXH_MESSB ;  A2SJZ5, PDXH_METPP ;  B0JI39, PDXH_MICAN ;
DR   A0QBI8, PDXH_MYCA1 ;  P65683, PDXH_MYCBO ;  A1KLV7, PDXH_MYCBP ;
DR   C1AF78, PDXH_MYCBT ;  A4T792, PDXH_MYCGI ;  O33065, PDXH_MYCLE ;
DR   Q742K7, PDXH_MYCPA ;  A0R420, PDXH_MYCS2 ;  A3Q628, PDXH_MYCSJ ;
DR   A1ULM8, PDXH_MYCSK ;  Q1B3H2, PDXH_MYCSS ;  A5U5V8, PDXH_MYCTA ;
DR   P65682, PDXH_MYCTU ;  A1TF46, PDXH_MYCVP ;  P21159, PDXH_MYXXA ;
DR   Q1DCS1, PDXH_MYXXD ;  Q5F8V2, PDXH_NEIG1 ;  B4RM90, PDXH_NEIG2 ;
DR   A9M007, PDXH_NEIM0 ;  Q9JTZ1, PDXH_NEIMA ;  Q9JYZ5, PDXH_NEIMB ;
DR   A1KUI2, PDXH_NEIMF ;  Q1QQ51, PDXH_NITHX ;  Q3SV02, PDXH_NITWN ;
DR   Q5Z236, PDXH_NOCFA ;  A1SEM4, PDXH_NOCSJ ;  B2IX27, PDXH_NOSP7 ;
DR   Q8YXG5, PDXH_NOSS1 ;  Q2GCC6, PDXH_NOVAD ;  A6WWA8, PDXH_OCHA4 ;
DR   A1B0C6, PDXH_PARDP ;  A7HR80, PDXH_PARL1 ;  Q4FN05, PDXH_PELUB ;
DR   Q7N3W5, PDXH_PHOLL ;  Q6LFS0, PDXH_PHOPR ;  A1VRL0, PDXH_POLNA ;
DR   Q126S5, PDXH_POLSJ ;  A4SWL7, PDXH_POLSQ ;  B2RHS7, PDXH_PORG3 ;
DR   Q7MU50, PDXH_PORGI ;  A2CDU4, PDXH_PROM3 ;  B4EWL7, PDXH_PROMH ;
DR   Q7V3Y6, PDXH_PROMM ;  Q48LQ7, PDXH_PSE14 ;  Q15R35, PDXH_PSEA6 ;
DR   A6V9E9, PDXH_PSEA7 ;  B7UXE2, PDXH_PSEA8 ;  Q02IL5, PDXH_PSEAB ;
DR   Q9I4S5, PDXH_PSEAE ;  Q1IDT9, PDXH_PSEE4 ;  Q4KH71, PDXH_PSEF5 ;
DR   C3K863, PDXH_PSEFS ;  Q3IDP4, PDXH_PSEHT ;  A4XS85, PDXH_PSEMY ;
DR   A5VZL6, PDXH_PSEP1 ;  Q3KGY4, PDXH_PSEPF ;  B0KUA9, PDXH_PSEPG ;
DR   Q88NS5, PDXH_PSEPK ;  B1J1C4, PDXH_PSEPW ;  Q87XR0, PDXH_PSESM ;
DR   Q4ZPN9, PDXH_PSEU2 ;  A4VJR0, PDXH_PSEU5 ;  Q4FS02, PDXH_PSYA2 ;
DR   Q1QC15, PDXH_PSYCK ;  A1SUY2, PDXH_PSYIN ;  A5WEW5, PDXH_PSYWF ;
DR   Q1LK07, PDXH_RALME ;  B2U826, PDXH_RALPJ ;  B3PSA1, PDXH_RHIE6 ;
DR   Q2KBN4, PDXH_RHIEC ;  Q1MKJ4, PDXH_RHIL3 ;  Q986A0, PDXH_RHILO ;
DR   B5ZSU2, PDXH_RHILW ;  Q92RH8, PDXH_RHIME ;  C3MHI2, PDXH_RHISN ;
DR   Q7UKQ9, PDXH_RHOBA ;  Q21WR9, PDXH_RHOFD ;  Q2J0U5, PDXH_RHOP2 ;
DR   Q07HS0, PDXH_RHOP5 ;  Q6NAI9, PDXH_RHOPA ;  Q21A86, PDXH_RHOPB ;
DR   Q13BJ4, PDXH_RHOPS ;  B3QIK5, PDXH_RHOPT ;  Q2RR21, PDXH_RHORT ;
DR   A3PIG5, PDXH_RHOS1 ;  Q3J3Y3, PDXH_RHOS4 ;  Q0S6R1, PDXH_RHOSR ;
DR   Q163Z1, PDXH_ROSDO ;  Q1ATH8, PDXH_RUBXD ;  A1AW86, PDXH_RUTMC ;
DR   Q21IG1, PDXH_SACD2 ;  A4F7G2, PDXH_SACEN ;  B5F6J9, PDXH_SALA4 ;
DR   A8M0C0, PDXH_SALAI ;  Q57PI9, PDXH_SALCH ;  B5FIF5, PDXH_SALDC ;
DR   B5QV11, PDXH_SALEP ;  B5RAL1, PDXH_SALG2 ;  B4THC5, PDXH_SALHS ;
DR   B4T585, PDXH_SALNS ;  Q5PIK6, PDXH_SALPA ;  A9N035, PDXH_SALPB ;
DR   C0Q5T4, PDXH_SALPC ;  B5BKC1, PDXH_SALPK ;  Q2S544, PDXH_SALRD ;
DR   B4TV07, PDXH_SALSV ;  Q8Z6Q2, PDXH_SALTI ;  Q8ZPM9, PDXH_SALTY ;
DR   A8GDX9, PDXH_SERP5 ;  A1S710, PDXH_SHEAM ;  B8EAI0, PDXH_SHEB2 ;
DR   A3D3G4, PDXH_SHEB5 ;  A6WM67, PDXH_SHEB8 ;  A9KY72, PDXH_SHEB9 ;
DR   Q12LW9, PDXH_SHEDO ;  Q083L3, PDXH_SHEFN ;  B0TQX6, PDXH_SHEHH ;
DR   A3QDE1, PDXH_SHELP ;  Q8ED71, PDXH_SHEON ;  A8H5G0, PDXH_SHEPA ;
DR   A4Y5Z1, PDXH_SHEPC ;  A0KVP0, PDXH_SHESA ;  A8FWJ0, PDXH_SHESH ;
DR   Q0HJY0, PDXH_SHESM ;  Q0HW76, PDXH_SHESR ;  A1RKK6, PDXH_SHESW ;
DR   B1KRD7, PDXH_SHEWM ;  B2U2D8, PDXH_SHIB3 ;  Q320Z5, PDXH_SHIBS ;
DR   Q32FD5, PDXH_SHIDS ;  Q0T4D9, PDXH_SHIF8 ;  P0AFI8, PDXH_SHIFL ;
DR   Q3Z1Z4, PDXH_SHISS ;  Q5LRI7, PDXH_SILPO ;  Q1GHI5, PDXH_SILST ;
DR   A6U6T5, PDXH_SINMW ;  Q2NT03, PDXH_SODGM ;  Q1GVE7, PDXH_SPHAL ;
DR   A5VFM5, PDXH_SPHWW ;  Q82GN9, PDXH_STRAW ;  Q9K3V7, PDXH_STRCO ;
DR   P74211, PDXH_SYNY3 ;  C5BN92, PDXH_TERTT ;  Q8DLZ5, PDXH_THEEB ;
DR   Q47TD1, PDXH_THEFY ;  A1WL02, PDXH_VEREI ;  A5CX08, PDXH_VESOH ;
DR   A5F176, PDXH_VIBC3 ;  Q9KKM4, PDXH_VIBCH ;  C3LWZ1, PDXH_VIBCM ;
DR   Q5DYB5, PDXH_VIBF1 ;  B5EVT2, PDXH_VIBFM ;  A7N7P0, PDXH_VIBHB ;
DR   Q87FE9, PDXH_VIBPA ;  B7VPY4, PDXH_VIBSL ;  Q8D510, PDXH_VIBVU ;
DR   Q7MBT9, PDXH_VIBVY ;  Q8D2L7, PDXH_WIGBR ;  Q73G09, PDXH_WOLPM ;
DR   Q8PI89, PDXH_XANAC ;  Q3BQS3, PDXH_XANC5 ;  Q4UX84, PDXH_XANC8 ;
DR   Q8P6X5, PDXH_XANCP ;  Q2P6C7, PDXH_XANOM ;  Q5H3H2, PDXH_XANOR ;
DR   A7II77, PDXH_XANP2 ;  Q9PDP2, PDXH_XYLFA ;  Q87DU7, PDXH_XYLFT ;
DR   A1JNV9, PDXH_YERE8 ;  A7FHL9, PDXH_YERP3 ;  Q1C790, PDXH_YERPA ;
DR   Q8ZE19, PDXH_YERPE ;  A9QZ96, PDXH_YERPG ;  Q1CIM4, PDXH_YERPN ;
DR   Q66A48, PDXH_YERPS ;  Q9RNP3, PDXH_ZYMMO ;  Q5E9K3, PNPO_BOVIN ;
DR   Q54YS6, PNPO_DICDI ;  Q9NVS9, PNPO_HUMAN ;  Q91XF0, PNPO_MOUSE ;
DR   O88794, PNPO_RAT   ;  O06553, Y1155_MYCTU;
//
ID   1.4.3.6
DE   Transferred entry: 1.4.3.21 and 1.4.3.22.
//
ID   1.4.3.7
DE   D-glutamate oxidase.
AN   D-glutamic oxidase.
CA   D-glutamate + H(2)O + O(2) = 2-oxoglutarate + NH(3) + H(2)O(2).
//
ID   1.4.3.8
DE   Ethanolamine oxidase.
CA   Ethanolamine + H(2)O + O(2) = glycolaldehyde + NH(3) + H(2)O(2).
CF   Cobalt.
//
ID   1.4.3.9
DE   Transferred entry: 1.4.3.4.
//
ID   1.4.3.10
DE   Putrescine oxidase.
CA   Putrescine + O(2) + H(2)O = 4-aminobutanal + NH(3) + H(2)O(2).
CF   FAD.
CC   -!- 4-aminobutanal condenses non-enzymically to 1-pyrroline.
DR   P40974, PUO_KOCRO  ;
//
ID   1.4.3.11
DE   L-glutamate oxidase.
CA   L-glutamate + O(2) + H(2)O = 2-oxoglutarate + NH(3) + H(2)O(2).
CF   FAD.
CC   -!- The enzyme from Azotobacter previously listed under this number,
CC       which did not produce H(2)O(2), was a crude cell-free extract which
CC       probably contained catalase.
//
ID   1.4.3.12
DE   Cyclohexylamine oxidase.
CA   Cyclohexylamine + O(2) + H(2)O = cyclohexanone + NH(3) + H(2)O(2).
CF   FAD.
CC   -!- Some other cyclic amines can act instead of cyclohexylamine, but not
CC       simple aliphatic and aromatic amides.
//
ID   1.4.3.13
DE   Protein-lysine 6-oxidase.
AN   Lysyl oxidase.
CA   Peptidyl-L-lysyl-peptide + O(2) + H(2)O = peptidyl-allysyl-peptide +
CA   NH(3) + H(2)O(2).
CC   -!- Also acts on protein 5-hydroxylysine.
CC   -!- Catalyzes the final known enzymic step required for collagen and
CC       elastin cross-linking in the biosynthesis of normal mature
CC       extracellular matrices.
CC   -!- These reactions play an important role for the development,
CC       elasticity and extensibility of connective tissue.
CC   -!- Also active on free amines, such as cadaverine or benzylamine.
PR   PROSITE; PDOC00716;
DR   P33072, LYOX_BOVIN ;  Q05063, LYOX_CHICK ;  P28300, LYOX_HUMAN ;
DR   P28301, LYOX_MOUSE ;  P45845, LYOX_PIG   ;  P16636, LYOX_RAT   ;
//
ID   1.4.3.14
DE   L-lysine oxidase.
CA   L-lysine + O(2) + H(2)O = 6-amino-2-oxohexanoate + NH(3) + H(2)O(2).
CF   FAD.
CC   -!- Also acts, more slowly, on L-ornithine, L-phenylalanine, L-arginine
CC       and L-histidine.
//
ID   1.4.3.15
DE   D-glutamate(D-aspartate) oxidase.
CA   D-glutamate + H(2)O + O(2) = 2-oxoglutarate + NH(3) + H(2)O(2).
CF   FAD.
CC   -!- D-glutamate and D-aspartate are oxidized at the same rate.
CC   -!- Other D-monoaminodicarboxylates, and other D- and L-amino acids,
CC       are not oxidized.
//
ID   1.4.3.16
DE   L-aspartate oxidase.
AN   LASPO.
CA   L-aspartate + O(2) = iminosuccinate + H(2)O(2).
CF   FAD.
CC   -!- L-aspartate oxidase catalyzes the first step in the de novo
CC       biosynthesis of NAD(+) in some bacteria.
CC   -!- O(2) can be replaced by fumarate as electron acceptor, yielding
CC       succinate.
CC   -!- The ability of the enzyme to use both O(2) and fumarate in cofactor
CC       reoxidation enables it to function under both aerobic and anaerobic
CC       conditions.
CC   -!- Iminosuccinate can either be hydrolyzed to form oxaloacetate and
CC       NH(3) or can be used by EC 2.5.1.72 in the production of quinolinate.
DR   Q8XWM7, NADB1_RALSO;  Q8XQG4, NADB2_RALSO;  Q8U8J4, NADB_AGRT5 ;
DR   O66973, NADB_AQUAE ;  Q9KDJ5, NADB_BACHD ;  P38032, NADB_BACSU ;
DR   Q9A4C3, NADB_CAUCR ;  Q97K95, NADB_CLOAB ;  Q8XNE2, NADB_CLOPE ;
DR   Q8XA23, NADB_ECO57 ;  P10902, NADB_ECOLI ;  Q9HNZ0, NADB_HALSA ;
DR   Q929Z2, NADB_LISIN ;  Q8Y5N4, NADB_LISMO ;  P65500, NADB_MYCBO ;
DR   Q49617, NADB_MYCLE ;  P65499, NADB_MYCTU ;  Q9JSX4, NADB_NEIMA ;
DR   Q9K107, NADB_NEIMB ;  Q8YXJ6, NADB_NOSS1 ;  Q51363, NADB_PSEAE ;
DR   Q9V2R0, NADB_PYRAB ;  Q8TZL4, NADB_PYRFU ;  O57765, NADB_PYRHO ;
DR   Q98AV8, NADB_RHILO ;  Q92R32, NADB_RHIME ;  Q59767, NADB_RHORU ;
DR   Q8Z4K0, NADB_SALTI ;  Q8ZMX9, NADB_SALTY ;  Q9X8N8, NADB_STRCO ;
DR   Q97ZC5, NADB_SULSO ;  Q972D2, NADB_SULTO ;  P74562, NADB_SYNY3 ;
DR   Q9KPA4, NADB_VIBCH ;  Q9PC57, NADB_XYLFA ;  Q87D19, NADB_XYLFT ;
DR   Q8ZD80, NADB_YERPE ;
//
ID   1.4.3.17
DE   Transferred entry: 1.3.3.10.
//
ID   1.4.3.18
DE   Deleted entry.
//
ID   1.4.3.19
DE   Glycine oxidase.
CA   (1) Glycine + H(2)O + O(2) = glyoxylate + NH(3) + H(2)O(2).
CA   (2) D-alanine + H(2)O + O(2) = pyruvate + NH(3) + H(2)O(2).
CA   (3) Sarcosine + H(2)O + O(2) = glyoxylate + methylamine + H(2)O(2).
CA   (4) N-ethylglycine + H(2)O + O(2) = glyoxylate + ethylamine + H(2)O(2).
CF   FAD.
CC   -!- The enzyme from Bacillus subtilis is active with glycine, sarcosine,
CC       N-ethylglycine, D-alanine, D-alpha-aminobutyrate, D-proline,
CC       D-pipecolate and N-methyl-D-alanine.
CC   -!- It differs from EC 1.4.3.3 due to its activity on sarcosine and
CC       D-pipecolate.
DR   O31616, GLOX_BACSU ;
//
ID   1.4.3.20
DE   L-lysine 6-oxidase.
AN   L-lysine-epsilon-oxidase.
AN   Lod.
AN   Marinocine.
CA   L-lysine + O(2) + H(2)O = (S)-2-amino-6-oxohexanoate + H(2)O(2) + NH(3).
CC   -!- Differs from EC 1.4.3.13 by using free L-lysine rather than the
CC       protein-bound form.
CC   -!- N(2)-acetyl-L-lysine is also a substrate, but N(6)-acetyl-L-lysine,
CC       which has an acetyl group at position 6, is not.
CC   -!- Also acts on L-ornithine, D-lysine and 4-hydroxy-L-lysine, but more
CC       slowly.
CC   -!- The amines cadaverine and putrescine are not substrates.
//
ID   1.4.3.21
DE   Primary-amine oxidase.
AN   Amine oxidase.
AN   Amine oxidase (copper-containing).
AN   Benzylamine oxidase.
AN   CAO.
AN   Copper amine oxidase.
CA   RCH(2)NH(2) + H(2)O + O(2) = RCHO + NH(3) + H(2)O(2).
CC   -!- A group of enzymes that oxidize primary monoamines but have little or
CC       no activity toward diamines, such as histamine, or toward secondary
CC       and tertiary amines.
CC   -!- They are copper quinoproteins (2,4,5-trihydroxyphenylalanine quinone)
CC       and, unlike EC 1.4.3.4, are sensitive to inhibition by carbonyl-group
CC       reagents, such as semicarbazide.
CC   -!- In some mammalian tissues the enzyme also functions as a vascular-
CC       adhesion protein (VAP-1).
CC   -!- Formerly EC 1.4.3.6.
DR   Q07121, AMO1_ARTS1 ;  Q07123, AMO2_ARTS1 ;  O42890, AMOH1_SCHPO;
DR   Q9P7F2, AMOH2_SCHPO;  Q8H1H9, AMO_ARATH  ;  P46883, AMO_ECOLI  ;
DR   P49250, AMO_ENTAE  ;  P80695, AMO_KLEOX  ;  P49252, AMO_LENCU  ;
DR   Q43077, AMO_PEA    ;  P12807, AMO_PICAN  ;  O75106, AOC2_HUMAN ;
DR   Q812C9, AOC2_MOUSE ;  Q9TTK6, AOC3_BOVIN ;  Q16853, AOC3_HUMAN ;
DR   O70423, AOC3_MOUSE ;  Q5R9I0, AOC3_PONAB ;  O08590, AOC3_RAT   ;
DR   Q29437, AOCX_BOVIN ;  O46406, AOCY_BOVIN ;  P46881, PAOX_ARTGO ;
//
ID   1.4.3.22
DE   Diamine oxidase.
AN   Amine oxidase.
AN   Amine oxidase (copper-containing).
AN   CAO.
AN   Copper amine oxidase.
AN   Cu-containing amine oxidase.
AN   Diamino oxhydrase.
AN   Histaminase.
AN   Histamine deaminase.
AN   Semicarbazide-sensitive amine oxidase.
AN   SSAO.
CA   Histamine + H(2)O + O(2) = (imidazol-4-yl)acetaldehyde + NH(3) +
CA   H(2)O(2).
CC   -!- A group of enzymes that oxidize diamines, such as histamine, and also
CC       some primary monoamines but have little or no activity toward
CC       secondary and tertiary amines.
CC   -!- They are copper quinoproteins (2,4,5-trihydroxyphenylalanine quinone)
CC       and, like EC 1.4.3.21 but unlike EC 1.4.3.4, they are sensitive to
CC       inhibition by carbonyl-group reagents, such as semicarbazide.
CC   -!- Formerly EC 1.4.3.6.
DR   P19801, ABP1_HUMAN ;  Q8JZQ5, ABP1_MOUSE ;  Q9TRC7, ABP1_PIG   ;
DR   P36633, ABP1_RAT   ;  Q12556, AMO1_ASPNG ;  Q59118, AMOH_ARTGO ;
//
ID   1.4.3.23
DE   7-chloro-L-tryptophan oxidase.
CA   7-chloro-L-tryptophan + O(2) = 2-imino-3-(7-chloroindol-3-yl)propanoate +
CA   H(2)O(2).
CC   -!- This enzyme catalyzes a step in the biosynthesis of rebeccamycin,
CC       an indolocarbazole alkaloid produced by the actinobacterium
CC       Lechevalieria aerocolonigenes.
CC   -!- During catalysis, the bound FAD is reoxidized at the expense of
CC       molecular oxygen, producing one molecule of hydrogen peroxide.
CC   -!- The enzyme shows significant preference for 7-chloro-L-tryptophan
CC       over L-tryptophan.
//
ID   1.4.4.1
DE   Transferred entry: 1.21.4.1.
//
ID   1.4.4.2
DE   Glycine dehydrogenase (decarboxylating).
AN   Glycine cleavage system P-protein.
AN   Glycine decarboxylase.
AN   Glycine-cleavage complex P-protein.
CA   Glycine + H-protein-lipoyllysine = H-protein-S-
CA   aminomethyldihydrolipoyllysine + CO(2).
CF   Pyridoxal 5'-phosphate.
CC   -!- A component, with EC 2.1.2.10 and EC 1.8.1.4, of the glycine cleavage
CC       system, previously known as glycine synthase.
CC   -!- The glycine cleavage system is composed of four components that only
CC       loosely associate: the P protein (EC 1.4.4.2), the T protein
CC       (EC 2.1.2.10), the L protein (EC 1.8.1.4) and the lipoyl-bearing H
CC       protein.
DR   O80988, GCSP1_ARATH;  Q486J6, GCSP1_COLP3;  Q9I137, GCSP1_PSEAE;
DR   Q4K7Q8, GCSP1_PSEF5;  Q3K7X5, GCSP1_PSEPF;  Q88P65, GCSP1_PSEPK;
DR   Q94B78, GCSP2_ARATH;  Q47XG2, GCSP2_COLP3;  Q9HTX7, GCSP2_PSEAE;
DR   Q4K416, GCSP2_PSEF5;  Q3K4Z1, GCSP2_PSEPF;  Q88CI9, GCSP2_PSEPK;
DR   Q1INU0, GCSPA_ACIBL;  C1F935, GCSPA_ACIC5;  Q9YA15, GCSPA_AERPE;
DR   Q0VLA8, GCSPA_ALCBS;  B8JDY8, GCSPA_ANAD2;  Q2IQD6, GCSPA_ANADE;
DR   A7HDC9, GCSPA_ANADF;  B4UGZ3, GCSPA_ANASK;  B7GHD3, GCSPA_ANOFW;
DR   O67193, GCSPA_AQUAE;  A8HT29, GCSPA_AZOC5;  A7Z6M3, GCSPA_BACA2;
DR   C3P8D4, GCSPA_BACAA;  C3LKQ3, GCSPA_BACAC;  A0RIL0, GCSPA_BACAH;
DR   Q81M07, GCSPA_BACAN;  B7JMV0, GCSPA_BACC0;  Q730W2, GCSPA_BACC1;
DR   B7IXL3, GCSPA_BACC2;  C1ERU9, GCSPA_BACC3;  B7HB99, GCSPA_BACC4;
DR   B7HNZ0, GCSPA_BACC7;  A7GSN7, GCSPA_BACCN;  B9IXL8, GCSPA_BACCQ;
DR   Q818M4, GCSPA_BACCR;  Q634V7, GCSPA_BACCZ;  Q9K935, GCSPA_BACHD;
DR   Q6HDT7, GCSPA_BACHK;  Q65HG0, GCSPA_BACLD;  A8FF40, GCSPA_BACP2;
DR   Q5WF31, GCSPA_BACSK;  P54376, GCSPA_BACSU;  A9VH11, GCSPA_BACWK;
DR   B2IGK3, GCSPA_BEII9;  C0ZBW6, GCSPA_BREBN;  Q3AET5, GCSPA_CARHZ;
DR   B8H4V4, GCSPA_CAUCN;  Q9A353, GCSPA_CAUCR;  B0T014, GCSPA_CAUSK;
DR   Q3APU1, GCSPA_CHLCH;  B3EH28, GCSPA_CHLL2;  B3QM32, GCSPA_CHLP8;
DR   A1BE03, GCSPA_CHLPD;  B3QUT6, GCSPA_CHLT3;  Q8KC05, GCSPA_CHLTE;
DR   B5Y9D4, GCSPA_COPPD;  B6J4T7, GCSPA_COXB1;  B6J2H7, GCSPA_COXB2;
DR   A9KC19, GCSPA_COXBN;  A9NA77, GCSPA_COXBR;  Q83B08, GCSPA_COXBU;
DR   C6C0V0, GCSPA_DESAD;  B8IYW9, GCSPA_DESDA;  Q311A7, GCSPA_DESDG;
DR   B8FT31, GCSPA_DESHD;  Q24TH5, GCSPA_DESHY;  C4XJB9, GCSPA_DESMR;
DR   Q6ARJ7, GCSPA_DESPS;  A4J2F8, GCSPA_DESRM;  Q72C59, GCSPA_DESVH;
DR   B8DP96, GCSPA_DESVM;  A1VE02, GCSPA_DESVV;  B5YFB8, GCSPA_DICT6;
DR   B8E2E7, GCSPA_DICTD;  Q2N886, GCSPA_ERYLH;  B1YLN7, GCSPA_EXIS2;
DR   P49361, GCSPA_FLAPR;  B0TZJ6, GCSPA_FRAP2;  Q14J40, GCSPA_FRAT1;
DR   A7NAH8, GCSPA_FRATF;  Q2A4V1, GCSPA_FRATH;  B2SFM3, GCSPA_FRATM;
DR   A0Q587, GCSPA_FRATN;  Q0BN71, GCSPA_FRATO;  Q5NHN8, GCSPA_FRATT;
DR   A4IZK6, GCSPA_FRATW;  B5EAW7, GCSPA_GEOBB;  Q5KX77, GCSPA_GEOKA;
DR   B9M3X6, GCSPA_GEOSF;  C6DYX1, GCSPA_GEOSM;  C5D4A1, GCSPA_GEOSW;
DR   A4IQV4, GCSPA_GEOTN;  A5GCZ8, GCSPA_GEOUR;  A1WWA5, GCSPA_HALHL;
DR   B8D1D5, GCSPA_HALOH;  B0R5Y6, GCSPA_HALS3;  Q9HPJ9, GCSPA_HALSA;
DR   Q0BYP2, GCSPA_HYPNA;  Q5X8W3, GCSPA_LEGPA;  A5I9T5, GCSPA_LEGPC;
DR   Q5ZZ95, GCSPA_LEGPH;  Q5X0A6, GCSPA_LEGPL;  Q92C05, GCSPA_LISIN;
DR   C1L2Q5, GCSPA_LISMC;  Q71ZX3, GCSPA_LISMF;  B8DFX9, GCSPA_LISMH;
DR   Q8Y7D4, GCSPA_LISMO;  A0AIF0, GCSPA_LISW6;  B1HSN6, GCSPA_LYSSC;
DR   B9E6R9, GCSPA_MACCJ;  Q2W9A3, GCSPA_MAGSA;  A0L7X6, GCSPA_MAGSM;
DR   Q0AMJ2, GCSPA_MARMM;  Q60BW4, GCSPA_METCA;  A4YHB7, GCSPA_METS5;
DR   B8EPH9, GCSPA_METSB;  Q2RH48, GCSPA_MOOTA;  Q0AEP9, GCSPA_NITEC;
DR   Q82WQ4, GCSPA_NITEU;  Q2YCK1, GCSPA_NITMU;  Q2G781, GCSPA_NOVAD;
DR   Q8CXE0, GCSPA_OCEIH;  A7HQY0, GCSPA_PARL1;  Q6MEJ2, GCSPA_PARUW;
DR   Q3B2G3, GCSPA_PELLD;  B4SE02, GCSPA_PELPB;  B4RF16, GCSPA_PHEZH;
DR   B4S5J4, GCSPA_PROA2;  A4SG06, GCSPA_PROVI;  Q9UXT0, GCSPA_PYRAB;
DR   Q8TZJ3, GCSPA_PYRFU;  O57708, GCSPA_PYRHO;  Q5JGX5, GCSPA_PYRKO;
DR   B6IXI3, GCSPA_RHOCS;  Q2RPV1, GCSPA_RHORT;  Q02BS4, GCSPA_SOLUE;
DR   A9FQM4, GCSPA_SORC5;  Q1GRZ2, GCSPA_SPHAL;  A5V9T6, GCSPA_SPHWW;
DR   A7X2S0, GCSPA_STAA1;  A6U207, GCSPA_STAA2;  Q2FGI6, GCSPA_STAA3;
DR   Q2FY34, GCSPA_STAA8;  A5IT64, GCSPA_STAA9;  Q5HFM3, GCSPA_STAAC;
DR   P64217, GCSPA_STAAM;  P64218, GCSPA_STAAN;  Q6GGG3, GCSPA_STAAR;
DR   Q6G930, GCSPA_STAAS;  Q8NWC9, GCSPA_STAAW;  B9DNN6, GCSPA_STACT;
DR   Q5HP13, GCSPA_STAEQ;  Q8CMM0, GCSPA_STAES;  Q4L6N6, GCSPA_STAHJ;
DR   A3DNJ9, GCSPA_STAMF;  Q49XY0, GCSPA_STAS1;  Q4J915, GCSPA_SULAC;
DR   C3N5G1, GCSPA_SULIA;  C4KH27, GCSPA_SULIK;  C3MPT5, GCSPA_SULIL;
DR   C3MUU8, GCSPA_SULIM;  C3NHN8, GCSPA_SULIN;  C3NE25, GCSPA_SULIY;
DR   Q97ZI8, GCSPA_SULSO;  Q972C1, GCSPA_SULTO;  Q0AVH8, GCSPA_SYNWW;
DR   Q9HII1, GCSPA_THEAC;  C5A7J1, GCSPA_THEGJ;  Q9WY56, GCSPA_THEMA;
DR   B6YT11, GCSPA_THEON;  A5IKK8, GCSPA_THEP1;  B9KZ42, GCSPA_THERP;
DR   B1L9T9, GCSPA_THESQ;  Q8RCW1, GCSPA_THETN;  Q97C05, GCSPA_THEVO;
DR   Q3SMB8, GCSPA_THIDA;  B8GN16, GCSPA_THISH;  B1GYV7, GCSPA_UNCTG;
DR   A7IHE9, GCSPA_XANP2;  Q9YA18, GCSPB_AERPE;  A8MEG7, GCSPB_ALKOO;
DR   O67740, GCSPB_AQUAE;  A7Z6M2, GCSPB_BACA2;  C3P8D3, GCSPB_BACAA;
DR   C3LKQ2, GCSPB_BACAC;  A0RIK9, GCSPB_BACAH;  Q81M08, GCSPB_BACAN;
DR   B7JMU9, GCSPB_BACC0;  P62029, GCSPB_BACC1;  B7IXL2, GCSPB_BACC2;
DR   C1ERU8, GCSPB_BACC3;  B7HB98, GCSPB_BACC4;  B7HNY9, GCSPB_BACC7;
DR   A7GSN6, GCSPB_BACCN;  B9IXL7, GCSPB_BACCQ;  Q818M5, GCSPB_BACCR;
DR   Q634V8, GCSPB_BACCZ;  Q9K936, GCSPB_BACHD;  Q6HDT8, GCSPB_BACHK;
DR   Q65HG1, GCSPB_BACLD;  Q5WF32, GCSPB_BACSK;  P54377, GCSPB_BACSU;
DR   A9VH10, GCSPB_BACWK;  C0ZBW7, GCSPB_BREBN;  Q9A354, GCSPB_CAUCR;
DR   Q3AQ15, GCSPB_CHLCH;  B3EEC8, GCSPB_CHLL2;  A1BJA7, GCSPB_CHLPD;
DR   B3QS77, GCSPB_CHLT3;  Q8KAN3, GCSPB_CHLTE;  B6J4T8, GCSPB_COXB1;
DR   B6J2H6, GCSPB_COXB2;  A9KC20, GCSPB_COXBN;  A9NA76, GCSPB_COXBR;
DR   Q83B09, GCSPB_COXBU;  A4J2F9, GCSPB_DESRM;  B1YLN8, GCSPB_EXIS2;
DR   A7HLP1, GCSPB_FERNB;  P49362, GCSPB_FLAPR;  B0TZJ5, GCSPB_FRAP2;
DR   B2SFM4, GCSPB_FRATM;  A0Q588, GCSPB_FRATN;  A4IZK5, GCSPB_FRATW;
DR   Q9HPK0, GCSPB_HALSA;  C5CF44, GCSPB_KOSOT;  Q5X8W5, GCSPB_LEGPA;
DR   A5I9T3, GCSPB_LEGPC;  Q5ZZ97, GCSPB_LEGPH;  Q5X0A8, GCSPB_LEGPL;
DR   Q92C04, GCSPB_LISIN;  C1L2Q6, GCSPB_LISMC;  Q71ZX2, GCSPB_LISMF;
DR   B8DFX8, GCSPB_LISMH;  Q8Y7D3, GCSPB_LISMO;  A0AIF1, GCSPB_LISW6;
DR   B1HSN5, GCSPB_LYSSC;  Q60BW5, GCSPB_METCA;  Q0AEQ0, GCSPB_NITEC;
DR   Q82WQ3, GCSPB_NITEU;  Q2YCK3, GCSPB_NITMU;  Q3J846, GCSPB_NITOC;
DR   Q8CXE1, GCSPB_OCEIH;  B4SB96, GCSPB_PELPB;  B4S3N4, GCSPB_PROA2;
DR   A4SCK8, GCSPB_PROVI;  Q9UXT1, GCSPB_PYRAB;  Q8TZJ2, GCSPB_PYRFU;
DR   O57709, GCSPB_PYRHO;  Q5JGX6, GCSPB_PYRKO;  Q7UNH1, GCSPB_RHOBA;
DR   A7X2R9, GCSPB_STAA1;  A6U206, GCSPB_STAA2;  Q2FGI7, GCSPB_STAA3;
DR   Q2FY35, GCSPB_STAA8;  A5IT63, GCSPB_STAA9;  Q2YSZ4, GCSPB_STAAB;
DR   Q5HFM4, GCSPB_STAAC;  A6QH79, GCSPB_STAAE;  P64219, GCSPB_STAAM;
DR   P99168, GCSPB_STAAN;  Q6GGG4, GCSPB_STAAR;  Q6G931, GCSPB_STAAS;
DR   A8Z474, GCSPB_STAAT;  Q8NWD0, GCSPB_STAAW;  Q5HP14, GCSPB_STAEQ;
DR   Q8CMM1, GCSPB_STAES;  Q4L6N5, GCSPB_STAHJ;  A3DNK0, GCSPB_STAMF;
DR   Q49XX9, GCSPB_STAS1;  C3N5G2, GCSPB_SULIA;  C4KH28, GCSPB_SULIK;
DR   C3MPT6, GCSPB_SULIL;  C3MUU9, GCSPB_SULIM;  C3NHN7, GCSPB_SULIN;
DR   C3NE26, GCSPB_SULIY;  Q97ZI9, GCSPB_SULSO;  Q972C0, GCSPB_SULTO;
DR   Q0AVH9, GCSPB_SYNWW;  B7IF24, GCSPB_THEAB;  Q9HII2, GCSPB_THEAC;
DR   C5A7J0, GCSPB_THEGJ;  A8F8M6, GCSPB_THELT;  A6LP69, GCSPB_THEM4;
DR   Q9WY57, GCSPB_THEMA;  B9K6R4, GCSPB_THENN;  B6YT12, GCSPB_THEON;
DR   A5IKK7, GCSPB_THEP1;  B1L9T8, GCSPB_THESQ;  P62030, GCSPB_THET2;
DR   Q5SKW7, GCSPB_THET8;  Q8RCW2, GCSPB_THETN;  Q97C04, GCSPB_THEVO;
DR   Q3SMC1, GCSPB_THIDA;  B8GN14, GCSPB_THISH;  P62031, GCSPB_TREDE;
DR   B1GYV8, GCSPB_UNCTG;  B9JFK7, GCSP_AGRRK ;  Q8UFD6, GCSP_AGRT5 ;
DR   B9JWI2, GCSP_AGRVS ;  B2UNH4, GCSP_AKKM8 ;  B6ES35, GCSP_ALISL ;
DR   Q3M9G1, GCSP_ANAVT ;  Q5NZ93, GCSP_AROAE ;  Q5LDN2, GCSP_BACFN ;
DR   Q64UQ7, GCSP_BACFR ;  Q8A8M0, GCSP_BACTN ;  Q6G2F1, GCSP_BARHE ;
DR   Q6FYZ7, GCSP_BARQU ;  Q6MPZ6, GCSP_BDEBA ;  Q2KYL7, GCSP_BORA1 ;
DR   Q7WP29, GCSP_BORBR ;  Q7W1C4, GCSP_BORPA ;  A9I7K9, GCSP_BORPD ;
DR   Q7W0E3, GCSP_BORPE ;  Q89I86, GCSP_BRAJA ;  A5EMM2, GCSP_BRASB ;
DR   A4YXQ9, GCSP_BRASO ;  B2SAU5, GCSP_BRUA1 ;  Q2YKX9, GCSP_BRUA2 ;
DR   P62920, GCSP_BRUAB ;  A9MC11, GCSP_BRUC2 ;  C0RLN1, GCSP_BRUMB ;
DR   P62921, GCSP_BRUME ;  A5VV25, GCSP_BRUO2 ;  A9WZ23, GCSP_BRUSI ;
DR   Q8FVU9, GCSP_BRUSU ;  B1YQQ1, GCSP_BURA4 ;  Q1BRE8, GCSP_BURCA ;
DR   B1JSZ2, GCSP_BURCC ;  A0K321, GCSP_BURCH ;  B4EF26, GCSP_BURCJ ;
DR   Q0BJI1, GCSP_BURCM ;  A9ACU3, GCSP_BURM1 ;  A3MQP3, GCSP_BURM7 ;
DR   A2S6F6, GCSP_BURM9 ;  Q62FN1, GCSP_BURMA ;  A1V8N7, GCSP_BURMS ;
DR   A3P0U7, GCSP_BURP0 ;  Q3JY08, GCSP_BURP1 ;  A3NF00, GCSP_BURP6 ;
DR   B2T7I8, GCSP_BURPP ;  Q63PL2, GCSP_BURPS ;  Q39KU1, GCSP_BURS3 ;
DR   Q2STK2, GCSP_BURTA ;  A4JA69, GCSP_BURVG ;  Q13SR6, GCSP_BURXL ;
DR   P15505, GCSP_CHICK ;  Q7NSJ5, GCSP_CHRVO ;  A8APB1, GCSP_CITK8 ;
DR   Q46VZ5, GCSP_CUPPJ ;  Q47D81, GCSP_DECAR ;  Q9RTF5, GCSP_DEIRA ;
DR   Q54KM7, GCSP_DICDI ;  A8LIH2, GCSP_DINSH ;  A7ZR12, GCSP_ECO24 ;
DR   B7UHV1, GCSP_ECO27 ;  B7MM89, GCSP_ECO45 ;  B7LF89, GCSP_ECO55 ;
DR   Q8XD33, GCSP_ECO57 ;  B5YQ95, GCSP_ECO5E ;  B7NHW4, GCSP_ECO7I ;
DR   B7MZ55, GCSP_ECO81 ;  B7LYG7, GCSP_ECO8A ;  C5A0H5, GCSP_ECOBW ;
DR   B1XEJ0, GCSP_ECODH ;  A8A444, GCSP_ECOHS ;  A1AF92, GCSP_ECOK1 ;
DR   Q0TDU9, GCSP_ECOL5 ;  Q8FE67, GCSP_ECOL6 ;  B1IT99, GCSP_ECOLC ;
DR   P33195, GCSP_ECOLI ;  B7N7E6, GCSP_ECOLU ;  B6I736, GCSP_ECOSE ;
DR   B1LDA3, GCSP_ECOSM ;  Q1R7C8, GCSP_ECOUT ;  C5BAT0, GCSP_EDWI9 ;
DR   A4WE55, GCSP_ENT38 ;  A7MR85, GCSP_ENTS8 ;  Q6D974, GCSP_ERWCT ;
DR   B7LPB7, GCSP_ESCF3 ;  O49850, GCSP_FLAAN ;  A5FMT0, GCSP_FLAJ1 ;
DR   O49852, GCSP_FLATR ;  Q5FRY0, GCSP_GLUOX ;  A0M5D4, GCSP_GRAFK ;
DR   Q2SFI6, GCSP_HAHCH ;  P23378, GCSP_HUMAN ;  Q5R192, GCSP_IDILO ;
DR   Q28L73, GCSP_JANSC ;  B5XUD5, GCSP_KLEP3 ;  A6TDR5, GCSP_KLEP7 ;
DR   Q04PM7, GCSP_LEPBJ ;  Q055P8, GCSP_LEPBL ;  Q72VI8, GCSP_LEPIC ;
DR   Q8F937, GCSP_LEPIN ;  Q91W43, GCSP_MOUSE ;  A0QGN2, GCSP_MYCA1 ;
DR   Q7VET8, GCSP_MYCBO ;  A1KJP4, GCSP_MYCBP ;  C1APA9, GCSP_MYCBT ;
DR   A4TA90, GCSP_MYCGI ;  B8ZSN5, GCSP_MYCLB ;  O32915, GCSP_MYCLE ;
DR   Q73ZQ6, GCSP_MYCPA ;  A5U3J9, GCSP_MYCTA ;  Q50601, GCSP_MYCTU ;
DR   Q5F761, GCSP_NEIG1 ;  B4RN40, GCSP_NEIG2 ;  A9M1P7, GCSP_NEIM0 ;
DR   Q9JT86, GCSP_NEIMA ;  A1KV85, GCSP_NEIMF ;  Q1QMW0, GCSP_NITHX ;
DR   Q3ST46, GCSP_NITWN ;  Q5YWV4, GCSP_NOCFA ;  B2J427, GCSP_NOSP7 ;
DR   Q8YNF9, GCSP_NOSS1 ;  P26969, GCSP_PEA   ;  C6D8X1, GCSP_PECCP ;
DR   Q4FMV1, GCSP_PELUB ;  Q7N199, GCSP_PHOLL ;  Q6LHN5, GCSP_PHOPR ;
DR   Q6A9R8, GCSP_PROAC ;  A2C5D4, GCSP_PROM1 ;  A2CDR0, GCSP_PROM3 ;
DR   Q7V9K4, GCSP_PROMA ;  B4F0N7, GCSP_PROMH ;  Q7V411, GCSP_PROMM ;
DR   Q46IC1, GCSP_PROMT ;  Q48ME3, GCSP_PSE14 ;  C3JYR1, GCSP_PSEFS ;
DR   Q3IFW1, GCSP_PSEHT ;  Q887L5, GCSP_PSESM ;  Q4ZXH2, GCSP_PSEU2 ;
DR   A4VRT4, GCSP_PSEU5 ;  Q4FTK9, GCSP_PSYA2 ;  Q1QCL7, GCSP_PSYCK ;
DR   A1SY74, GCSP_PSYIN ;  Q1LHM2, GCSP_RALME ;  B2UG82, GCSP_RALPJ ;
DR   Q8XU98, GCSP_RALSO ;  B3PP20, GCSP_RHIE6 ;  Q2K813, GCSP_RHIEC ;
DR   Q1MG62, GCSP_RHIL3 ;  Q98LT6, GCSP_RHILO ;  B5ZQP8, GCSP_RHILW ;
DR   Q92Q11, GCSP_RHIME ;  Q8G9M2, GCSP_RHOFA ;  Q07R90, GCSP_RHOP5 ;
DR   Q6N344, GCSP_RHOPA ;  A3PI15, GCSP_RHOS1 ;  Q3J4D4, GCSP_RHOS4 ;
DR   A4WUX2, GCSP_RHOS5 ;  B9KNU3, GCSP_RHOSK ;  Q16AX0, GCSP_ROSDO ;
DR   Q21HU3, GCSP_SACD2 ;  B5F5H7, GCSP_SALA4 ;  A9MRH2, GCSP_SALAR ;
DR   B5FUG6, GCSP_SALDC ;  B5QXI0, GCSP_SALEP ;  B5RE14, GCSP_SALG2 ;
DR   B4TGX3, GCSP_SALHS ;  B4T548, GCSP_SALNS ;  A9N3N1, GCSP_SALPB ;
DR   C0PY26, GCSP_SALPC ;  Q8Z3X0, GCSP_SALTI ;  Q8ZM76, GCSP_SALTY ;
DR   Q09785, GCSP_SCHPO ;  A8GIR9, GCSP_SERP5 ;  A1S965, GCSP_SHEAM ;
DR   B8EB45, GCSP_SHEB2 ;  A3D085, GCSP_SHEB5 ;  A6WSL1, GCSP_SHEB8 ;
DR   A9L330, GCSP_SHEB9 ;  Q07YC9, GCSP_SHEFN ;  B0TSG5, GCSP_SHEHH ;
DR   A3QHI0, GCSP_SHELP ;  Q8EIQ6, GCSP_SHEON ;  A8H7S9, GCSP_SHEPA ;
DR   A4YAD8, GCSP_SHEPC ;  A0L103, GCSP_SHESA ;  A8FZK4, GCSP_SHESH ;
DR   Q0HEX2, GCSP_SHESM ;  Q0HZ28, GCSP_SHESR ;  A1RFY8, GCSP_SHESW ;
DR   B1KG87, GCSP_SHEWM ;  B2U0S0, GCSP_SHIB3 ;  Q31WG4, GCSP_SHIBS ;
DR   Q32BW5, GCSP_SHIDS ;  Q0T0Z5, GCSP_SHIF8 ;  Q83QA2, GCSP_SHIFL ;
DR   Q3YXW7, GCSP_SHISS ;  A6U8Q3, GCSP_SINMW ;  Q2NRF0, GCSP_SODGM ;
DR   O49954, GCSP_SOLTU ;  Q827D7, GCSP_STRAW ;  Q9AK84, GCSP_STRCO ;
DR   B1W4G3, GCSP_STRGG ;  B4SS67, GCSP_STRM5 ;  B2FQE7, GCSP_STRMK ;
DR   Q7U3Q5, GCSP_SYNPX ;  A5GWN4, GCSP_SYNR3 ;  Q3AUM0, GCSP_SYNS9 ;
DR   P74416, GCSP_SYNY3 ;  C5BNY8, GCSP_TERTT ;  Q8DII3, GCSP_THEEB ;
DR   Q83IA7, GCSP_TROW8 ;  Q83GV1, GCSP_TROWT ;  C5CRW8, GCSP_VARPS ;
DR   A5EYY8, GCSP_VIBC3 ;  C3LUU7, GCSP_VIBCM ;  Q5DZM3, GCSP_VIBF1 ;
DR   B5EUH1, GCSP_VIBFM ;  A7N5C4, GCSP_VIBHB ;  Q87I05, GCSP_VIBPA ;
DR   Q8D7G7, GCSP_VIBVU ;  Q7MEH9, GCSP_VIBVY ;  Q8PN59, GCSP_XANAC ;
DR   Q3BW89, GCSP_XANC5 ;  Q4URZ4, GCSP_XANC8 ;  Q8PBK7, GCSP_XANCP ;
DR   Q2P021, GCSP_XANOM ;  Q9PDJ4, GCSP_XYLFA ;  Q87DR1, GCSP_XYLFT ;
DR   P49095, GCSP_YEAST ;  A1JPN3, GCSP_YERE8 ;  A7FF21, GCSP_YERP3 ;
DR   Q1CB42, GCSP_YERPA ;  B2K0Q3, GCSP_YERPB ;  Q8ZHI8, GCSP_YERPE ;
DR   A9R4K8, GCSP_YERPG ;  Q1CEZ9, GCSP_YERPN ;  A4TIA7, GCSP_YERPP ;
DR   Q666R7, GCSP_YERPS ;  B1JNS8, GCSP_YERPY ;
//
ID   1.4.5.1
DE   D-amino acid dehydrogenase (quinone).
AN   DadA.
CA   A D-amino acid + H(2)O + a quinone = a 2-oxo acid + NH(3) + a quinol.
CF   FAD; Iron-sulfur.
CC   -!- This enzyme may be the same as EC 1.4.99.1.
//
ID   1.4.7.1
DE   Glutamate synthase (ferredoxin).
AN   Ferredoxin-dependent glutamate synthase.
CA   2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate +
CA   2 reduced ferredoxin + 2 H(+).
CF   Flavoprotein; Iron-sulfur.
PR   PROSITE; PDOC00406;
DR   Q9ZNZ7, GLTB1_ARATH;  Q9T0P4, GLTB2_ARATH;  Q06434, GLTB_ANTSP ;
DR   O19906, GLTB_CYACA ;  Q08258, GLTB_HORVU ;  P23225, GLTB_MAIZE ;
DR   Q69RJ0, GLTB_ORYSJ ;  P51375, GLTB_PORPU ;  Q1XDB2, GLTB_PORYE ;
DR   Q43155, GLTB_SPIOL ;  P55037, GLTB_SYNY3 ;  P55038, GLTS_SYNY3 ;
//
ID   1.4.98.1
DE   Methylamine dehydrogenase (amicyanin).
AN   Amine dehydrogenase.
AN   MADH.
AN   Methylamine dehydrogenase.
AN   Primary-amine dehydrogenase.
CA   Methylamine + H(2)O + amicyanin = formaldehyde + ammonia + reduced
CA   amicyanin.
CF   Tryptophan tryptophylquinone.
CC   -!- Formerly EC 1.14.99.3.
DR   Q49124, DHMH_METEA ;  Q50420, DHMH_METFK ;  Q59542, DHMH_METME ;
DR   P29894, DHMH_PARDE ;  P23006, DHMH_PARVE ;  P00372, DHML_METEA ;
DR   Q50425, DHML_METFK ;  Q59543, DHML_METME ;  P22619, DHML_PARDE ;
DR   P22641, DHML_PARVE ;
//
ID   1.4.99.1
DE   D-amino-acid dehydrogenase.
CA   A D-amino acid + H(2)O + acceptor = a 2-oxo acid + NH(3) + reduced
CA   acceptor.
CF   FAD.
CC   -!- Acts to some extent on all D-amino acids except D-aspartate and
CC       D-glutamate.
DR   Q9HTQ0, DADA1_PSEAE;  Q88EM0, DADA1_PSEPK;  Q8Y0W7, DADA1_RALSO;
DR   Q98F08, DADA1_RHILO;  Q9HU99, DADA2_PSEAE;  Q88CB1, DADA2_PSEPK;
DR   Q8XX54, DADA2_RALSO;  Q98B75, DADA2_RHILO;  Q981X2, DADA3_RHILO;
DR   Q6FFR5, DADA_ACIAD ;  B7H2E9, DADA_ACIB3 ;  B7I1Q9, DADA_ACIB5 ;
DR   B0VNF5, DADA_ACIBS ;  A3M0Z0, DADA_ACIBT ;  B0V6N4, DADA_ACIBY ;
DR   A0KJP1, DADA_AERHH ;  A4SNB0, DADA_AERS4 ;  B9JI94, DADA_AGRRK ;
DR   P58739, DADA_AGRT5 ;  B9K2I7, DADA_AGRVS ;  A8I711, DADA_AZOC5 ;
DR   C1DJZ7, DADA_AZOVD ;  Q7WI07, DADA_BORBR ;  Q7W641, DADA_BORPA ;
DR   A9IP97, DADA_BORPD ;  Q89T28, DADA_BRAJA ;  B2SDA2, DADA_BRUA1 ;
DR   Q2YIL0, DADA_BRUA2 ;  Q579E2, DADA_BRUAB ;  A9MCK4, DADA_BRUC2 ;
DR   C0RM68, DADA_BRUMB ;  Q8YD04, DADA_BRUME ;  A5VVJ0, DADA_BRUO2 ;
DR   A9WVT6, DADA_BRUSI ;  Q8FVC0, DADA_BRUSU ;  B1YV52, DADA_BURA4 ;
DR   Q1BY09, DADA_BURCA ;  B1JXT8, DADA_BURCC ;  A0K5P0, DADA_BURCH ;
DR   B4EAP1, DADA_BURCJ ;  Q0BH74, DADA_BURCM ;  A9ADT7, DADA_BURM1 ;
DR   A3MHR1, DADA_BURM7 ;  A2S4P8, DADA_BURM9 ;  Q62M46, DADA_BURMA ;
DR   A1V6K0, DADA_BURMS ;  A3NXU9, DADA_BURP0 ;  Q3JQ00, DADA_BURP1 ;
DR   A3NC12, DADA_BURP6 ;  B2JF25, DADA_BURP8 ;  B2T612, DADA_BURPP ;
DR   Q63S25, DADA_BURPS ;  Q39IE1, DADA_BURS3 ;  Q2SY06, DADA_BURTA ;
DR   A4JCJ3, DADA_BURVG ;  Q13VE3, DADA_BURXL ;  Q1QXY5, DADA_CHRSD ;
DR   Q7NWR6, DADA_CHRVO ;  A8AFS0, DADA_CITK8 ;  Q479B1, DADA_DECAR ;
DR   A9BU40, DADA_DELAS ;  A7ZKW0, DADA_ECO24 ;  B7UQ73, DADA_ECO27 ;
DR   B7MK86, DADA_ECO45 ;  B7LGU9, DADA_ECO55 ;  P0A6J7, DADA_ECO57 ;
DR   B7NJF1, DADA_ECO7I ;  B7MTW7, DADA_ECO81 ;  B7LXA3, DADA_ECO8A ;
DR   C4ZTN0, DADA_ECOBW ;  B1XA76, DADA_ECODH ;  A7ZZC3, DADA_ECOHS ;
DR   Q0TII6, DADA_ECOL5 ;  P0A6J6, DADA_ECOL6 ;  B1IUA3, DADA_ECOLC ;
DR   P0A6J5, DADA_ECOLI ;  B7N3Z3, DADA_ECOLU ;  B6I9Q0, DADA_ECOSE ;
DR   C5B9W5, DADA_EDWI9 ;  A4WBF2, DADA_ENT38 ;  O30745, DADA_ENTAE ;
DR   A7MKD3, DADA_ENTS8 ;  Q6D4N9, DADA_ERWCT ;  B2VJ51, DADA_ERWT9 ;
DR   B7LSJ5, DADA_ESCF3 ;  Q0BUV2, DADA_GRABC ;  B5XQ81, DADA_KLEP3 ;
DR   A6TAW4, DADA_KLEP7 ;  Q2W3H2, DADA_MAGSA ;  Q1H378, DADA_METFK ;
DR   B8IJ86, DADA_METNO ;  B1M860, DADA_METRJ ;  B0UBI8, DADA_METS4 ;
DR   Q5F5W1, DADA_NEIG1 ;  B4RR07, DADA_NEIG2 ;  A9M3T2, DADA_NEIM0 ;
DR   Q9JX24, DADA_NEIMA ;  Q9K1H5, DADA_NEIMB ;  A1KRK7, DADA_NEIMF ;
DR   A6WYV7, DADA_OCHA4 ;  A1B072, DADA_PARDP ;  C6DGU9, DADA_PECCP ;
DR   B4RBL4, DADA_PHEZH ;  Q7N3Z6, DADA_PHOLL ;  B4EXU2, DADA_PROMH ;
DR   Q48PZ1, DADA_PSE14 ;  Q1I2V6, DADA_PSEE4 ;  A4XNV3, DADA_PSEMY ;
DR   A5WAY8, DADA_PSEP1 ;  B0KQ74, DADA_PSEPG ;  B1J4P3, DADA_PSEPW ;
DR   Q88BB6, DADA_PSESM ;  Q4ZZW4, DADA_PSEU2 ;  A4VGT8, DADA_PSEU5 ;
DR   Q9RAE6, DADA_RHIL3 ;  Q2IZZ7, DADA_RHOP2 ;  A3PRF6, DADA_RHOS1 ;
DR   Q3IXK6, DADA_RHOS4 ;  B5F4E4, DADA_SALA4 ;  A9MP60, DADA_SALAR ;
DR   Q57NK9, DADA_SALCH ;  B5FTN1, DADA_SALDC ;  B5R2W7, DADA_SALEP ;
DR   B4TKD3, DADA_SALHS ;  B4SUJ5, DADA_SALNS ;  Q5PCU1, DADA_SALPA ;
DR   A9MVW7, DADA_SALPB ;  C0Q330, DADA_SALPC ;  B5BI50, DADA_SALPK ;
DR   B4TXX3, DADA_SALSV ;  Q8Z687, DADA_SALTI ;  Q8ZP17, DADA_SALTY ;
DR   A8GFF7, DADA_SERP5 ;  B2TZB5, DADA_SHIB3 ;  Q31ZN0, DADA_SHIBS ;
DR   Q32H27, DADA_SHIDS ;  Q0T5L2, DADA_SHIF8 ;  Q7UCT6, DADA_SHIFL ;
DR   Q3Z2V9, DADA_SHISS ;  A6UB96, DADA_SINMW ;  A5V4F9, DADA_SPHWW ;
DR   B4SIE4, DADA_STRM5 ;  B2FLQ1, DADA_STRMK ;  A5F3D0, DADA_VIBC3 ;
DR   Q9KTV1, DADA_VIBCH ;  C3LT39, DADA_VIBCM ;  B7VMK8, DADA_VIBSL ;
DR   Q8DF11, DADA_VIBVU ;  Q7MND7, DADA_VIBVY ;  Q8PGC9, DADA_XANAC ;
DR   Q3BNX3, DADA_XANC5 ;  Q4UQB4, DADA_XANC8 ;  B0RWG2, DADA_XANCB ;
DR   Q8P4Q9, DADA_XANCP ;  A7IHQ4, DADA_XANP2 ;  B2I8Y3, DADA_XYLF2 ;
DR   Q9PF27, DADA_XYLFA ;  B0U4V3, DADA_XYLFM ;  Q87AK0, DADA_XYLFT ;
DR   A1JQN9, DADA_YERE8 ;  A7FI92, DADA_YERP3 ;  Q1C7V0, DADA_YERPA ;
DR   B2K3Q3, DADA_YERPB ;  Q8ZEL7, DADA_YERPE ;  A9R9D3, DADA_YERPG ;
DR   Q1CJ86, DADA_YERPN ;  A4TJC4, DADA_YERPP ;  Q66AQ6, DADA_YERPS ;
DR   B1JLH4, DADA_YERPY ;
//
ID   1.4.99.2
DE   Taurine dehydrogenase.
CA   Taurine + H(2)O + acceptor = sulfoacetaldehyde + NH(3) + reduced
CA   acceptor.
//
ID   1.4.99.3
DE   Transferred entry: 1.4.98.1.
//
ID   1.4.99.4
DE   Aralkylamine dehydrogenase.
AN   Aromatic amine dehydrogenase.
CA   RCH(2)NH(2) + H(2)O + acceptor = RCHO + NH(3) + reduced acceptor.
CC   -!- Phenazine methosulfate can act as acceptor.
CC   -!- Acts on aromatic amines and, more slowly, on some long-chain
CC       aliphatic amines, but not on methylamine or ethylamine (cf.
CC       EC 1.4.98.1).
DR   P84887, AAUA_ALCFA ;  P84888, AAUB_ALCFA ;
//
ID   1.4.99.5
DE   Glycine dehydrogenase (cyanide-forming).
AN   HCN synthase.
AN   Hydrogen cyanide synthase.
CA   Glycine + 2 A = HCN + CO(2) + 2 AH(2).
CF   FAD.
CC   -!- The enzyme is membrane-bound, and the 2-electron acceptor is a
CC       component of the respiratory chain.
CC   -!- The enzyme can act with various artificial electron acceptors,
CC       including phenazine methosulfate.
//
ID   1.5.1.1
DE   Pyrroline-2-carboxylate reductase.
CA   L-proline + NAD(P)(+) = 1-pyrroline-2-carboxylate + NAD(P)H.
CC   -!- Reduces 1-pyrroline-2-carboxylate to L-proline and also 1,2-
CC       didehydropiperidine-2-carboxylate to L-pipecolate.
//
ID   1.5.1.2
DE   Pyrroline-5-carboxylate reductase.
AN   P5CR.
CA   L-proline + NAD(P)(+) = 1-pyrroline-5-carboxylate + NAD(P)H.
CC   -!- Also reduces 1-pyrroline-3-hydroxy-5-carboxylate to L-hydroxyproline.
PR   PROSITE; PDOC00451;
DR   P54904, P5CR1_ARATH;  E0TY11, P5CR1_BACPZ;  P0CI77, P5CR1_BACSU;
DR   Q58DT4, P5CR1_BOVIN;  Q54IL7, P5CR1_DICDI;  P32322, P5CR1_HUMAN;
DR   Q922W5, P5CR1_MOUSE;  Q5R9X6, P5CR1_PONAB;  P54552, P5CR2_BACSU;
DR   Q17QJ7, P5CR2_BOVIN;  Q55E34, P5CR2_DICDI;  Q96C36, P5CR2_HUMAN;
DR   Q4R6W7, P5CR2_MACFA;  Q922Q4, P5CR2_MOUSE;  Q5RAQ3, P5CR2_PONAB;
DR   Q6AY23, P5CR2_RAT  ;  Q00777, P5CR3_BACSU;  Q58D08, P5CR3_BOVIN;
DR   Q5SPD7, P5CR3_DANRE;  Q53H96, P5CR3_HUMAN;  Q4R531, P5CR3_MACFA;
DR   Q9DCC4, P5CR3_MOUSE;  Q5PQJ6, P5CR3_RAT  ;  A1L2Q8, P5CR3_XENLA;
DR   O04016, P5CR_ACTCH ;  O66553, P5CR_AQUAE ;  Q20848, P5CR_CAEEL ;
DR   P0C1E4, P5CR_CORGL ;  P0C1E5, P5CR_CORML ;  P0A9L8, P5CR_ECOLI ;
DR   P43869, P5CR_HAEIN ;  Q9ZK56, P5CR_HELPJ ;  O25773, P5CR_HELPY ;
DR   Q9HH99, P5CR_METAC ;  P22350, P5CR_METSM ;  P46725, P5CR_MYCLE ;
DR   Q11141, P5CR_MYCTU ;  Q12641, P5CR_NEUCR ;  Q9CPE8, P5CR_PASMU ;
DR   Q04708, P5CR_PEA   ;  P22008, P5CR_PSEAE ;  Q9P7Y7, P5CR_SCHPO ;
DR   P0A9L9, P5CR_SHIFL ;  P17817, P5CR_SOYBN ;  Q5HFR9, P5CR_STAAC ;
DR   Q99TZ0, P5CR_STAAM ;  Q7A5G8, P5CR_STAAN ;  Q6GGJ5, P5CR_STAAR ;
DR   Q6G961, P5CR_STAAS ;  Q7A0U1, P5CR_STAAW ;  Q5HP48, P5CR_STAEQ ;
DR   Q8CP51, P5CR_STAES ;  Q4L6K3, P5CR_STAHJ ;  Q49XV0, P5CR_STAS1 ;
DR   P74572, P5CR_SYNY3 ;  P54893, P5CR_THET2 ;  P27771, P5CR_TREPA ;
DR   P52053, P5CR_VIBAL ;  P32263, P5CR_YEAST ;  Q12740, P5CR_ZALAR ;
//
ID   1.5.1.3
DE   Dihydrofolate reductase.
AN   Tetrahydrofolate dehydrogenase.
CA   5,6,7,8-tetrahydrofolate + NADP(+) = 7,8-dihydrofolate + NADPH.
CC   -!- The enzyme from animals and some micro-organisms also slowly reduces
CC       folate to 5,6,7,8-tetrahydrofolate.
CC   -!- Formerly EC 1.5.1.4.
PR   PROSITE; PDOC00072;
DR   Q05762, DRTS1_ARATH;  Q05763, DRTS2_ARATH;  Q23695, DRTS_CRIFA ;
DR   P45350, DRTS_DAUCA ;  P16126, DRTS_LEIAM ;  P07382, DRTS_LEIMA ;
DR   O81395, DRTS_MAIZE ;  Q5UQG3, DRTS_MIMIV ;  Q2QRX6, DRTS_ORYSJ ;
DR   Q27828, DRTS_PARTE ;  Q27713, DRTS_PLABA ;  P20712, DRTS_PLACH ;
DR   P13922, DRTS_PLAFK ;  O02604, DRTS_PLAVI ;  P46103, DRTS_PLAVN ;
DR   P51820, DRTS_SOYBN ;  Q07422, DRTS_TOXGO ;  Q27783, DRTS_TRYBB ;
DR   Q27793, DRTS_TRYCR ;  Q04515, DYR10_ECOLX;  Q59408, DYR13_ECOLX;
DR   P78218, DYR15_ECOLX;  P00382, DYR1_ECOLX ;  Q5V3R2, DYR1_HALMA ;
DR   P00383, DYR21_ECOLX;  P00384, DYR22_ECOLX;  P05794, DYR23_ECOLX;
DR   Q5V600, DYR2_HALMA ;  P12833, DYR3_SALTY ;  P11731, DYR5_ECOLX ;
DR   P95524, DYR6_PROMI ;  P27422, DYR7_ECOLX ;  P0ABQ7, DYR8_ECOLX ;
DR   P0ABQ8, DYR8_SHISO ;  Q59397, DYR9_ECOLX ;  P13955, DYRA_STAAU ;
DR   P28019, DYR_AEDAL  ;  P11045, DYR_BACSU  ;  P00376, DYR_BOVIN  ;
DR   P04382, DYR_BPT4   ;  P57243, DYR_BUCAI  ;  Q8K9Z8, DYR_BUCAP  ;
DR   Q89AV2, DYR_BUCBP  ;  Q93341, DYR_CAEEL  ;  P22906, DYR_CANAL  ;
DR   P00378, DYR_CHICK  ;  P31073, DYR_CITFR  ;  Q07801, DYR_CRYNJ  ;
DR   P17719, DYR_DROME  ;  P0ABQ5, DYR_ECOL6  ;  P0ABQ4, DYR_ECOLI  ;
DR   O62583, DYR_ENCCU  ;  P31074, DYR_ENTAE  ;  P00380, DYR_ENTFC  ;
DR   P43791, DYR_HAEIN  ;  P15093, DYR_HALVD  ;  Q9U8B8, DYR_HELVI  ;
DR   P00374, DYR_HUMAN  ;  P00381, DYR_LACCA  ;  Q59487, DYR_LACLA  ;
DR   P04753, DYR_MESAU  ;  P00375, DYR_MOUSE  ;  P0A547, DYR_MYCBO  ;
DR   P47470, DYR_MYCGE  ;  Q9CBW1, DYR_MYCLE  ;  P78028, DYR_MYCPN  ;
DR   Q98Q32, DYR_MYCPU  ;  P0A546, DYR_MYCTU  ;  P04174, DYR_NEIGO  ;
DR   Q9JSQ9, DYR_NEIMA  ;  Q9K168, DYR_NEIMB  ;  P00377, DYR_PIG    ;
DR   P16184, DYR_PNECA  ;  Q920D2, DYR_RAT    ;  P36591, DYR_SCHPO  ;
DR   P0ABQ6, DYR_SHIFL  ;  P09503, DYR_SHV21  ;  P27421, DYR_SHV24  ;
DR   P22573, DYR_SHV2C  ;  Q5HFZ7, DYR_STAAC  ;  P0A016, DYR_STAAM  ;
DR   P99079, DYR_STAAN  ;  Q6GGY1, DYR_STAAR  ;  Q6G9D5, DYR_STAAS  ;
DR   P0A017, DYR_STAAU  ;  Q8NWQ9, DYR_STAAW  ;  P0C0P0, DYR_STAEP  ;
DR   Q5HPB1, DYR_STAEQ  ;  P0C0P1, DYR_STAES  ;  Q54277, DYR_STAHA  ;
DR   Q54801, DYR_STRPN  ;  Q60034, DYR_THEMA  ;  Q9PR30, DYR_UREPA  ;
DR   P07807, DYR_YEAST  ;  A8AGY5, FOLM_CITK8 ;  A7ZM66, FOLM_ECO24 ;
DR   P0AFS4, FOLM_ECO57 ;  A8A0E8, FOLM_ECOHS ;  A1ABF1, FOLM_ECOK1 ;
DR   Q0THM2, FOLM_ECOL5 ;  Q8FHB1, FOLM_ECOL6 ;  B1IQY4, FOLM_ECOLC ;
DR   P0AFS3, FOLM_ECOLI ;  B1LET0, FOLM_ECOSM ;  Q1RBJ2, FOLM_ECOUT ;
DR   A4W9Z4, FOLM_ENT38 ;  A6T8N3, FOLM_KLEP7 ;  Q320W2, FOLM_SHIBS ;
DR   Q32G72, FOLM_SHIDS ;  Q0T4H1, FOLM_SHIF8 ;  Q83RC9, FOLM_SHIFL ;
DR   Q3Z1V9, FOLM_SHISS ;
//
ID   1.5.1.4
DE   Transferred entry: 1.5.1.3.
//
ID   1.5.1.5
DE   Methylenetetrahydrofolate dehydrogenase (NADP(+)).
CA   5,10-methylenetetrahydrofolate + NADP(+) = 5,10-
CA   methenyltetrahydrofolate + NADPH.
PR   PROSITE; PDOC00616;
DR   O96553, C1TC_DROME ;  P11586, C1TC_HUMAN ;  Q922D8, C1TC_MOUSE ;
DR   Q5R8P0, C1TC_PONAB ;  P27653, C1TC_RAT   ;  Q8WZJ7, C1TC_SCHPO ;
DR   Q27772, C1TC_SPOFR ;  P07245, C1TC_YEAST ;  O43007, C1TM_SCHPO ;
DR   P09440, C1TM_YEAST ;  Q6F9E6, FOLD1_ACIAD;  A1R228, FOLD1_ARTAT;
DR   Q7WAC0, FOLD1_BORPA;  Q7VZC8, FOLD1_BORPE;  Q47ZE0, FOLD1_COLP3;
DR   Q1J118, FOLD1_DEIGD;  Q24ZZ6, FOLD1_DESHY;  Q0RNE2, FOLD1_FRAAA;
DR   Q2JCX4, FOLD1_FRASC;  Q39Z32, FOLD1_GEOMG;  Q74GN1, FOLD1_GEOSL;
DR   Q5V3D9, FOLD1_HALMA;  Q74J95, FOLD1_LACJO;  Q1DA76, FOLD1_MYXXD;
DR   A1SED2, FOLD1_NOCSJ;  A1B5A7, FOLD1_PARDP;  Q48KZ8, FOLD1_PSE14;
DR   A4XTZ3, FOLD1_PSEMY;  B0KJG3, FOLD1_PSEPG;  Q88LI7, FOLD1_PSEPK;
DR   Q87YR0, FOLD1_PSESM;  Q4ZVN1, FOLD1_PSEU2;  Q2KCC6, FOLD1_RHIEC;
DR   Q989A7, FOLD1_RHILO;  Q92T88, FOLD1_RHIME;  Q0SFQ8, FOLD1_RHOSR;
DR   Q167Y9, FOLD1_ROSDO;  Q1AXT3, FOLD1_RUBXD;  A4FI92, FOLD1_SACEN;
DR   A8LWI0, FOLD1_SALAI;  A4X776, FOLD1_SALTO;  Q5LNV2, FOLD1_SILPO;
DR   A6U669, FOLD1_SINMW;  A5V4U1, FOLD1_SPHWW;  Q82QG3, FOLD1_STRAW;
DR   Q0AZF5, FOLD1_SYNWW;  Q31HQ4, FOLD1_THICR;  Q6F8N7, FOLD2_ACIAD;
DR   A1R451, FOLD2_ARTAT;  Q7W4Z7, FOLD2_BORPA;  Q7VVW3, FOLD2_BORPE;
DR   Q47XL6, FOLD2_COLP3;  Q1J0I3, FOLD2_DEIGD;  Q24UZ7, FOLD2_DESHY;
DR   Q0RI14, FOLD2_FRAAA;  Q2J9L3, FOLD2_FRASC;  Q39WH4, FOLD2_GEOMG;
DR   Q74EU7, FOLD2_GEOSL;  Q5V630, FOLD2_HALMA;  Q74IM0, FOLD2_LACJO;
DR   Q1D7Y2, FOLD2_MYXXD;  A1SMP7, FOLD2_NOCSJ;  A1BBS1, FOLD2_PARDP;
DR   Q48HJ1, FOLD2_PSE14;  A4XXZ2, FOLD2_PSEMY;  B0KLM9, FOLD2_PSEPG;
DR   Q88KM5, FOLD2_PSEPK;  Q883B5, FOLD2_PSESM;  Q4ZUA4, FOLD2_PSEU2;
DR   Q2JZV0, FOLD2_RHIEC;  Q987T6, FOLD2_RHILO;  Q92RY3, FOLD2_RHIME;
DR   Q0S375, FOLD2_RHOSR;  Q160C1, FOLD2_ROSDO;  Q1AVQ0, FOLD2_RUBXD;
DR   A4FP42, FOLD2_SACEN;  A8M449, FOLD2_SALAI;  A4XBC7, FOLD2_SALTO;
DR   Q5LT54, FOLD2_SILPO;  A6UB98, FOLD2_SINMW;  A5V807, FOLD2_SPHWW;
DR   Q82HR6, FOLD2_STRAW;  Q0AWX5, FOLD2_SYNWW;  Q31FY5, FOLD2_THICR;
DR   A4XY05, FOLD3_PSEMY;  Q160C0, FOLD3_ROSDO;  Q1AT41, FOLD3_RUBXD;
DR   A5VAA8, FOLD3_SPHWW;  B0C3J3, FOLD_ACAM1 ;  A9NE96, FOLD_ACHLI ;
DR   A1TPZ6, FOLD_ACIAC ;  Q1II76, FOLD_ACIBL ;  A3M846, FOLD_ACIBT ;
DR   A0LRU9, FOLD_ACIC1 ;  C1F683, FOLD_ACIC5 ;  A5G1W5, FOLD_ACICJ ;
DR   B9MIU6, FOLD_ACIET ;  B7JBX9, FOLD_ACIF2 ;  B5EJA0, FOLD_ACIF5 ;
DR   A1W7S2, FOLD_ACISJ ;  A3N0Q7, FOLD_ACTP2 ;  B3GXP3, FOLD_ACTP7 ;
DR   B0BPI2, FOLD_ACTPJ ;  A6VMD8, FOLD_ACTSZ ;  A0KJD4, FOLD_AERHH ;
DR   A4SNM0, FOLD_AERS4 ;  Q8UHU0, FOLD_AGRT5 ;  B2UM17, FOLD_AKKM8 ;
DR   Q0VQ92, FOLD_ALCBS ;  Q0AB42, FOLD_ALHEH ;  B6EIM4, FOLD_ALISL ;
DR   A6TPR4, FOLD_ALKMQ ;  A8MKZ5, FOLD_ALKOO ;  B4RV70, FOLD_ALTMD ;
DR   B3ESU1, FOLD_AMOA5 ;  Q2IQE1, FOLD_ANADE ;  A7HDC5, FOLD_ANADF ;
DR   Q5PBL6, FOLD_ANAMM ;  Q2GLF2, FOLD_ANAPZ ;  Q3M9M0, FOLD_ANAVT ;
DR   B7GHF9, FOLD_ANOFW ;  O67736, FOLD_AQUAE ;  A8ESH8, FOLD_ARCB4 ;
DR   Q5P922, FOLD_AROAE ;  Q9AGP6, FOLD_ARTGO ;  A0JTZ0, FOLD_ARTS2 ;
DR   A8I5P5, FOLD_AZOC5 ;  B6YRQ9, FOLD_AZOPC ;  A1K589, FOLD_AZOSB ;
DR   C1DHE7, FOLD_AZOVD ;  A7Z6J9, FOLD_BACA2 ;  C3P7W0, FOLD_BACAA ;
DR   C3LJV5, FOLD_BACAC ;  A0RIH3, FOLD_BACAH ;  Q81M50, FOLD_BACAN ;
DR   B7JM32, FOLD_BACC0 ;  Q731B2, FOLD_BACC1 ;  B7IXH2, FOLD_BACC2 ;
DR   C1ERQ4, FOLD_BACC3 ;  B7HB52, FOLD_BACC4 ;  B7HNU4, FOLD_BACC7 ;
DR   A7GSJ9, FOLD_BACCN ;  B9IXH4, FOLD_BACCQ ;  Q818R5, FOLD_BACCR ;
DR   Q635A3, FOLD_BACCZ ;  Q5LAX0, FOLD_BACFN ;  Q64RB7, FOLD_BACFR ;
DR   Q9K966, FOLD_BACHD ;  Q6HDY4, FOLD_BACHK ;  Q65HI8, FOLD_BACLD ;
DR   A8FF15, FOLD_BACP2 ;  Q5WCI9, FOLD_BACSK ;  P54382, FOLD_BACSU ;
DR   Q8A7B8, FOLD_BACTN ;  A6L2G2, FOLD_BACV8 ;  A9VGW3, FOLD_BACWK ;
DR   A1URL6, FOLD_BARBK ;  Q6G4F1, FOLD_BARHE ;  Q6G0I9, FOLD_BARQU ;
DR   A9IQD2, FOLD_BART1 ;  Q1LTX1, FOLD_BAUCH ;  Q6MI74, FOLD_BDEBA ;
DR   B8DUV2, FOLD_BIFA0 ;  A1A171, FOLD_BIFAA ;  B3DSS3, FOLD_BIFLD ;
DR   Q8G5L6, FOLD_BIFLO ;  B7GT00, FOLD_BIFLS ;  Q7VRB3, FOLD_BLOFL ;
DR   Q493A0, FOLD_BLOPB ;  Q2L1G0, FOLD_BORA1 ;  Q0SPD8, FOLD_BORAP ;
DR   Q7WJG1, FOLD_BORBR ;  O51057, FOLD_BORBU ;  B7J0W5, FOLD_BORBZ ;
DR   Q662Y6, FOLD_BORGA ;  A9ISZ5, FOLD_BORPD ;  C0R292, FOLD_BRAHW ;
DR   Q89WX9, FOLD_BRAJA ;  A5E8S0, FOLD_BRASB ;  A4YK09, FOLD_BRASO ;
DR   C0ZC05, FOLD_BREBN ;  B2SAP4, FOLD_BRUA1 ;  Q2YL33, FOLD_BRUA2 ;
DR   Q578R0, FOLD_BRUAB ;  A9MC67, FOLD_BRUC2 ;  C0RLT3, FOLD_BRUMB ;
DR   Q8YCL8, FOLD_BRUME ;  A5VV73, FOLD_BRUO2 ;  A9WZ75, FOLD_BRUSI ;
DR   Q8FVP6, FOLD_BRUSU ;  P57557, FOLD_BUCAI ;  Q8K979, FOLD_BUCAP ;
DR   Q89A92, FOLD_BUCBP ;  Q057D7, FOLD_BUCCC ;  B1YT42, FOLD_BURA4 ;
DR   Q1BHV3, FOLD_BURCA ;  B1JV19, FOLD_BURCC ;  A0K8R4, FOLD_BURCH ;
DR   B4EDU1, FOLD_BURCJ ;  Q0BDP0, FOLD_BURCM ;  A9AGS9, FOLD_BURM1 ;
DR   A3MLB7, FOLD_BURM7 ;  A2SAQ8, FOLD_BURM9 ;  Q62IX5, FOLD_BURMA ;
DR   A1V5P2, FOLD_BURMS ;  A3NX53, FOLD_BURP0 ;  Q3JQL8, FOLD_BURP1 ;
DR   A3NBC0, FOLD_BURP6 ;  B2T5N8, FOLD_BURPP ;  Q63SL6, FOLD_BURPS ;
DR   Q39ES6, FOLD_BURS3 ;  Q2SXF8, FOLD_BURTA ;  A4JG19, FOLD_BURVG ;
DR   Q13WX0, FOLD_BURXL ;  A4XLE0, FOLD_CALS8 ;  A7ZCH3, FOLD_CAMC1 ;
DR   A7GXK2, FOLD_CAMC5 ;  A0RQ49, FOLD_CAMFF ;  A7I254, FOLD_CAMHC ;
DR   A8FLR4, FOLD_CAMJ8 ;  A7H3N3, FOLD_CAMJD ;  Q0PA35, FOLD_CAMJE ;
DR   A1VZJ8, FOLD_CAMJJ ;  Q5HUU1, FOLD_CAMJR ;  Q3AAY6, FOLD_CARHZ ;
DR   B8H4A3, FOLD_CAUCN ;  Q9A8Y0, FOLD_CAUCR ;  B0T3F7, FOLD_CAUSK ;
DR   B3PHG5, FOLD_CELJU ;  A0RTU3, FOLD_CENSY ;  A9WJ10, FOLD_CHLAA ;
DR   Q5L644, FOLD_CHLAB ;  B8GC39, FOLD_CHLAD ;  Q3ASI0, FOLD_CHLCH ;
DR   Q823G2, FOLD_CHLCV ;  Q254F7, FOLD_CHLFF ;  B3ECA6, FOLD_CHLL2 ;
DR   Q9PKW1, FOLD_CHLMU ;  B3EJG9, FOLD_CHLPB ;  A1BF67, FOLD_CHLPD ;
DR   Q9Z8K3, FOLD_CHLPN ;  B9LD23, FOLD_CHLSY ;  B0B9I6, FOLD_CHLT2 ;
DR   B3QUL4, FOLD_CHLT3 ;  Q3KMU3, FOLD_CHLTA ;  B0BB65, FOLD_CHLTB ;
DR   O84081, FOLD_CHLTR ;  Q1QVV9, FOLD_CHRSD ;  Q7NWQ6, FOLD_CHRVO ;
DR   A8AJS4, FOLD_CITK8 ;  A5CU17, FOLD_CLAM3 ;  B0RDR2, FOLD_CLAMS ;
DR   Q97HC9, FOLD_CLOAB ;  A7FT56, FOLD_CLOB1 ;  C3KT80, FOLD_CLOB6 ;
DR   A6LU44, FOLD_CLOB8 ;  B2V4R7, FOLD_CLOBA ;  B2TRN5, FOLD_CLOBB ;
DR   A5I112, FOLD_CLOBH ;  C1FKP7, FOLD_CLOBJ ;  B1IIW9, FOLD_CLOBK ;
DR   A7GCL0, FOLD_CLOBL ;  B1KZC8, FOLD_CLOBM ;  B8I761, FOLD_CLOCE ;
DR   Q189R8, FOLD_CLOD6 ;  A5N5B5, FOLD_CLOK5 ;  A0Q0A0, FOLD_CLONN ;
DR   Q0TPD4, FOLD_CLOP1 ;  Q8XJD7, FOLD_CLOPE ;  A9KLS3, FOLD_CLOPH ;
DR   Q0SS01, FOLD_CLOPS ;  Q894G6, FOLD_CLOTE ;  A3DEE6, FOLD_CLOTH ;
DR   B5Y9D1, FOLD_COPPD ;  C3PLA3, FOLD_CORA7 ;  Q6NIZ6, FOLD_CORDI ;
DR   Q8FRU9, FOLD_COREF ;  A4QBY8, FOLD_CORGB ;  Q8NSM0, FOLD_CORGL ;
DR   Q4JTI3, FOLD_CORJK ;  B6J5U6, FOLD_COXB1 ;  B6J1Z2, FOLD_COXB2 ;
DR   A9KGQ5, FOLD_COXBN ;  A9NB47, FOLD_COXBR ;  Q83EK7, FOLD_COXBU ;
DR   Q0KBW5, FOLD_CUPNH ;  Q472L4, FOLD_CUPPJ ;  B3R4L6, FOLD_CUPTR ;
DR   B1WRW8, FOLD_CYAA5 ;  B8HXS0, FOLD_CYAP4 ;  B7KEP3, FOLD_CYAP7 ;
DR   B7JVV5, FOLD_CYAP8 ;  Q11UD1, FOLD_CYTH3 ;  Q47IX6, FOLD_DECAR ;
DR   Q3Z8K6, FOLD_DEHE1 ;  A5FRF1, FOLD_DEHSB ;  Q3ZX43, FOLD_DEHSC ;
DR   Q9RW02, FOLD_DEIRA ;  A9BWT7, FOLD_DELAS ;  B8FLE5, FOLD_DESAA ;
DR   C6BSL6, FOLD_DESAD ;  C0QAY0, FOLD_DESAH ;  B8J466, FOLD_DESDA ;
DR   Q316P9, FOLD_DESDG ;  C4XLR8, FOLD_DESMR ;  A8ZTQ4, FOLD_DESOH ;
DR   Q6ALZ5, FOLD_DESPS ;  A4J3F5, FOLD_DESRM ;  Q72F91, FOLD_DESVH ;
DR   B8DMA9, FOLD_DESVM ;  A1VGV4, FOLD_DESVV ;  A5EX57, FOLD_DICNV ;
DR   B5YA73, FOLD_DICT6 ;  B8E335, FOLD_DICTD ;  A8LIR3, FOLD_DINSH ;
DR   A7ZIT8, FOLD_ECO24 ;  B7UKK6, FOLD_ECO27 ;  B7ME52, FOLD_ECO45 ;
DR   B7L7F6, FOLD_ECO55 ;  Q8XCT6, FOLD_ECO57 ;  B5YPP4, FOLD_ECO5E ;
DR   B7NL23, FOLD_ECO7I ;  B7MRJ2, FOLD_ECO81 ;  B7M4N2, FOLD_ECO8A ;
DR   C4ZUX7, FOLD_ECOBW ;  B1XGC7, FOLD_ECODH ;  A7ZXI3, FOLD_ECOHS ;
DR   A1A8J4, FOLD_ECOK1 ;  Q0TKB2, FOLD_ECOL5 ;  Q8FK41, FOLD_ECOL6 ;
DR   B1IZ72, FOLD_ECOLC ;  P24186, FOLD_ECOLI ;  B7N983, FOLD_ECOLU ;
DR   B6I0H4, FOLD_ECOSE ;  B1LKE8, FOLD_ECOSM ;  Q1RF04, FOLD_ECOUT ;
DR   C5B8V3, FOLD_EDWI9 ;  Q3YRE3, FOLD_EHRCJ ;  Q2GHD8, FOLD_EHRCR ;
DR   Q5FG00, FOLD_EHRRG ;  Q5HAK8, FOLD_EHRRW ;  B2KB67, FOLD_ELUMP ;
DR   A4W7J0, FOLD_ENT38 ;  Q836W7, FOLD_ENTFA ;  A7MJZ6, FOLD_ENTS8 ;
DR   Q6D2E6, FOLD_ERWCT ;  B2VBD1, FOLD_ERWT9 ;  Q2N7E3, FOLD_ERYLH ;
DR   B7LJI7, FOLD_ESCF3 ;  C4ZBG7, FOLD_EUBR3 ;  B1YLQ1, FOLD_EXIS2 ;
DR   C4L3F6, FOLD_EXISA ;  A7HMQ2, FOLD_FERNB ;  A5FNE3, FOLD_FLAJ1 ;
DR   A6GZM5, FOLD_FLAPJ ;  B0U009, FOLD_FRAP2 ;  A8L893, FOLD_FRASN ;
DR   Q14HV5, FOLD_FRAT1 ;  A7NA91, FOLD_FRATF ;  Q2A535, FOLD_FRATH ;
DR   B2SF67, FOLD_FRATM ;  A0Q505, FOLD_FRATN ;  Q0BNF1, FOLD_FRATO ;
DR   Q5NGF3, FOLD_FRATT ;  A4IYR4, FOLD_FRATW ;  Q8RDM4, FOLD_FUSNN ;
DR   Q75TC1, FOLD_GEOKA ;  B9M769, FOLD_GEOSF ;  A4IQS0, FOLD_GEOTN ;
DR   A5GAM5, FOLD_GEOUR ;  Q7NJE8, FOLD_GLOVI ;  A9HEL1, FOLD_GLUDA ;
DR   Q5FST0, FOLD_GLUOX ;  A0M554, FOLD_GRAFK ;  Q7VM86, FOLD_HAEDU ;
DR   Q4QMI7, FOLD_HAEI8 ;  A5UAS4, FOLD_HAEIE ;  A5UHL4, FOLD_HAEIG ;
DR   P44313, FOLD_HAEIN ;  B8F605, FOLD_HAEPS ;  Q0I3S5, FOLD_HAES1 ;
DR   B0USU2, FOLD_HAES2 ;  Q2SK39, FOLD_HAHCH ;  A1WUN4, FOLD_HALHL ;
DR   B8D2H8, FOLD_HALOH ;  Q9HPY4, FOLD_HALSA ;  Q18GK1, FOLD_HALWD ;
DR   C4K7E4, FOLD_HAMD5 ;  Q17W13, FOLD_HELAH ;  Q7VGF6, FOLD_HELHP ;
DR   B0TFC9, FOLD_HELMI ;  Q1CTU9, FOLD_HELPH ;  Q9ZLQ4, FOLD_HELPJ ;
DR   P56467, FOLD_HELPY ;  A9AZP9, FOLD_HERA2 ;  A4G352, FOLD_HERAR ;
DR   B4U8W9, FOLD_HYDS0 ;  Q0BX67, FOLD_HYPNA ;  Q5QWH6, FOLD_IDILO ;
DR   A6SVR5, FOLD_JANMA ;  Q28TR2, FOLD_JANSC ;  A6WF54, FOLD_KINRD ;
DR   B5Y0K4, FOLD_KLEP3 ;  A6T5R4, FOLD_KLEP7 ;  B2GM30, FOLD_KOCRD ;
DR   C5CI88, FOLD_KOSOT ;  Q5FJG5, FOLD_LACAC ;  Q03RR1, FOLD_LACBA ;
DR   Q038F9, FOLD_LACC3 ;  B3WEY4, FOLD_LACCB ;  Q1G9H1, FOLD_LACDA ;
DR   Q049N0, FOLD_LACDB ;  B2GD67, FOLD_LACF3 ;  Q044I0, FOLD_LACGA ;
DR   A8YVX0, FOLD_LACH4 ;  Q9CH85, FOLD_LACLA ;  A2RLU5, FOLD_LACLM ;
DR   Q030A3, FOLD_LACLS ;  Q88WM8, FOLD_LACPL ;  A5VKR7, FOLD_LACRD ;
DR   B2G850, FOLD_LACRJ ;  Q1WUJ3, FOLD_LACS1 ;  Q38XU9, FOLD_LACSS ;
DR   C1D5X9, FOLD_LARHH ;  Q1MPZ8, FOLD_LAWIP ;  Q5X5Q9, FOLD_LEGPA ;
DR   A5IBF0, FOLD_LEGPC ;  Q5ZVZ1, FOLD_LEGPH ;  Q5WX38, FOLD_LEGPL ;
DR   Q6ADF1, FOLD_LEIXX ;  B0S8U6, FOLD_LEPBA ;  Q04SB2, FOLD_LEPBJ ;
DR   Q050D8, FOLD_LEPBL ;  B0SRN4, FOLD_LEPBP ;  Q72QT3, FOLD_LEPIC ;
DR   Q8F523, FOLD_LEPIN ;  B1N044, FOLD_LEUCK ;  Q03YZ6, FOLD_LEUMM ;
DR   Q92BZ4, FOLD_LISIN ;  C1L2R6, FOLD_LISMC ;  Q71ZW2, FOLD_LISMF ;
DR   B8DFW8, FOLD_LISMH ;  Q8Y7C5, FOLD_LISMO ;  A0AIG1, FOLD_LISW6 ;
DR   B1HRX9, FOLD_LYSSC ;  B9EAY2, FOLD_MACCJ ;  Q2VYZ7, FOLD_MAGSA ;
DR   A0LE04, FOLD_MAGSM ;  Q65RF1, FOLD_MANSM ;  A1U1Q5, FOLD_MARAV ;
DR   Q0ATP0, FOLD_MARMM ;  A6W1T1, FOLD_MARMS ;  Q6F1V0, FOLD_MESFL ;
DR   Q11M18, FOLD_MESSB ;  Q8TK95, FOLD_METAC ;  A7IAE1, FOLD_METB6 ;
DR   Q46A53, FOLD_METBF ;  Q12V26, FOLD_METBU ;  Q9X7F6, FOLD_METC4 ;
DR   Q1GXE6, FOLD_METFK ;  Q2FR55, FOLD_METHJ ;  Q8PZQ1, FOLD_METMA ;
DR   A3CWL0, FOLD_METMJ ;  B8GG34, FOLD_METPE ;  A2SHP8, FOLD_METPP ;
DR   A0B8J7, FOLD_METTP ;  B0JUP8, FOLD_MICAN ;  C5C958, FOLD_MICLC ;
DR   Q2RIB4, FOLD_MOOTA ;  A0QKM1, FOLD_MYCA1 ;  B3PMJ8, FOLD_MYCA5 ;
DR   B1MG21, FOLD_MYCA9 ;  Q7TWN0, FOLD_MYCBO ;  A1KP49, FOLD_MYCBP ;
DR   C1AHH2, FOLD_MYCBT ;  Q2SRE7, FOLD_MYCCT ;  Q6RX33, FOLD_MYCFO ;
DR   Q7NAE4, FOLD_MYCGA ;  P47259, FOLD_MYCGE ;  A4TET2, FOLD_MYCGI ;
DR   B8ZUV4, FOLD_MYCLB ;  O32879, FOLD_MYCLE ;  B2HDR8, FOLD_MYCMM ;
DR   Q6KID0, FOLD_MYCMO ;  Q6MSL3, FOLD_MYCMS ;  Q73UA5, FOLD_MYCPA ;
DR   Q8EV80, FOLD_MYCPE ;  P75096, FOLD_MYCPN ;  Q98QV3, FOLD_MYCPU ;
DR   A0QSY5, FOLD_MYCS2 ;  Q4A6B1, FOLD_MYCS5 ;  A3PVV6, FOLD_MYCSJ ;
DR   A1UC75, FOLD_MYCSK ;  Q1BCR8, FOLD_MYCSS ;  A5U830, FOLD_MYCTA ;
DR   O50385, FOLD_MYCTU ;  A0PNP3, FOLD_MYCUA ;  A1T5D0, FOLD_MYCVP ;
DR   Q3IRX3, FOLD_NATPD ;  B2A532, FOLD_NATTJ ;  B9L952, FOLD_NAUPA ;
DR   Q5F5D0, FOLD_NEIG1 ;  B4RQN5, FOLD_NEIG2 ;  A9M068, FOLD_NEIM0 ;
DR   Q9JWI9, FOLD_NEIMA ;  P0C277, FOLD_NEIMB ;  A1KWF4, FOLD_NEIMF ;
DR   Q2GCV3, FOLD_NEOSM ;  Q0AFN2, FOLD_NITEC ;  Q82XC3, FOLD_NITEU ;
DR   Q1QQJ9, FOLD_NITHX ;  A9A4N5, FOLD_NITMS ;  Q2YC56, FOLD_NITMU ;
DR   Q3J8Z0, FOLD_NITOC ;  A6Q2W6, FOLD_NITSB ;  Q3SVE4, FOLD_NITWN ;
DR   Q5YU63, FOLD_NOCFA ;  B2J442, FOLD_NOSP7 ;  Q8Z086, FOLD_NOSS1 ;
DR   Q2G338, FOLD_NOVAD ;  Q8EQ43, FOLD_OCEIH ;  A6X610, FOLD_OCHA4 ;
DR   Q04FB7, FOLD_OENOB ;  B6JAU5, FOLD_OLICO ;  B1ZYH0, FOLD_OPITP ;
DR   A5CF58, FOLD_ORITB ;  B3CTT4, FOLD_ORITI ;  A6L8J2, FOLD_PARD8 ;
DR   A7HSV9, FOLD_PARL1 ;  Q6MAH4, FOLD_PARUW ;  Q9CJR1, FOLD_PASMU ;
DR   C6DAX0, FOLD_PECCP ;  Q03FZ5, FOLD_PEDPA ;  Q3A1Q7, FOLD_PELCD ;
DR   Q3B4E2, FOLD_PELLD ;  B4SGR4, FOLD_PELPB ;  A1AL91, FOLD_PELPD ;
DR   A5D323, FOLD_PELTS ;  Q4FNW1, FOLD_PELUB ;  A9BIV9, FOLD_PETMO ;
DR   B4RE11, FOLD_PHEZH ;  Q7MZH1, FOLD_PHOLL ;  P51696, FOLD_PHOPO ;
DR   Q6LNV7, FOLD_PHOPR ;  Q6L046, FOLD_PICTO ;  A1VN60, FOLD_POLNA ;
DR   B1XUA6, FOLD_POLNS ;  Q12A51, FOLD_POLSJ ;  A4SWT5, FOLD_POLSQ ;
DR   Q7MVE9, FOLD_PORGI ;  B4S820, FOLD_PROA2 ;  Q6A6Z2, FOLD_PROAC ;
DR   A3PDH3, FOLD_PROM0 ;  A2C3L3, FOLD_PROM1 ;  A8G5D8, FOLD_PROM2 ;
DR   A2C873, FOLD_PROM3 ;  A9BB39, FOLD_PROM4 ;  A2BX55, FOLD_PROM5 ;
DR   Q31AF6, FOLD_PROM9 ;  Q7TVA3, FOLD_PROMA ;  B4F1G5, FOLD_PROMH ;
DR   Q7TUV8, FOLD_PROMM ;  Q7TU81, FOLD_PROMP ;  A2BRP7, FOLD_PROMS ;
DR   Q46K05, FOLD_PROMT ;  A4SER8, FOLD_PROVI ;  Q15R43, FOLD_PSEA6 ;
DR   A6V726, FOLD_PSEA7 ;  B7VB83, FOLD_PSEA8 ;  Q02KT7, FOLD_PSEAB ;
DR   Q9I2U6, FOLD_PSEAE ;  Q1ICB3, FOLD_PSEE4 ;  Q4K9J4, FOLD_PSEF5 ;
DR   Q3IF52, FOLD_PSEHT ;  A5W638, FOLD_PSEP1 ;  Q3K9W7, FOLD_PSEPF ;
DR   B1J675, FOLD_PSEPW ;  A4VL74, FOLD_PSEU5 ;  Q4FTX6, FOLD_PSYA2 ;
DR   Q1QD30, FOLD_PSYCK ;  A1SUX5, FOLD_PSYIN ;  A5WGG4, FOLD_PSYWF ;
DR   Q8ZZK1, FOLD_PYRAE ;  A4WMX1, FOLD_PYRAR ;  A3MXE6, FOLD_PYRCJ ;
DR   A1RQQ5, FOLD_PYRIL ;  Q1LP48, FOLD_RALME ;  B2UFY4, FOLD_RALPJ ;
DR   Q8XZ10, FOLD_RALSO ;  A9WM40, FOLD_RENSM ;  Q1MLB6, FOLD_RHIL3 ;
DR   Q93E15, FOLD_RHILT ;  Q6W210, FOLD_RHISN ;  Q7UNN9, FOLD_RHOBA ;
DR   O68031, FOLD_RHOCB ;  B6IVC0, FOLD_RHOCS ;  Q21WC0, FOLD_RHOFD ;
DR   Q2J3Z0, FOLD_RHOP2 ;  Q07VM6, FOLD_RHOP5 ;  Q6NCQ6, FOLD_RHOPA ;
DR   Q21D98, FOLD_RHOPB ;  Q13DA7, FOLD_RHOPS ;  B3QA91, FOLD_RHOPT ;
DR   Q2RWY4, FOLD_RHORT ;  A3PM50, FOLD_RHOS1 ;  Q3J049, FOLD_RHOS4 ;
DR   A4WQ13, FOLD_RHOS5 ;  B9KLK2, FOLD_RHOSK ;  C3PNI9, FOLD_RICAE ;
DR   A8GNK0, FOLD_RICAH ;  A8GW74, FOLD_RICB8 ;  Q1RHV0, FOLD_RICBR ;
DR   A8EYV5, FOLD_RICCK ;  Q92HY4, FOLD_RICCN ;  Q4ULM3, FOLD_RICFE ;
DR   A8F1N1, FOLD_RICM5 ;  Q9ZD32, FOLD_RICPR ;  C4K0H2, FOLD_RICPU ;
DR   B0BXN7, FOLD_RICRO ;  A8GS71, FOLD_RICRS ;  Q68WL9, FOLD_RICTY ;
DR   A7NHA9, FOLD_ROSCS ;  A5V1H2, FOLD_ROSS1 ;  A1AXA0, FOLD_RUTMC ;
DR   Q21JE9, FOLD_SACD2 ;  B5EYE2, FOLD_SALA4 ;  A9MLA4, FOLD_SALAR ;
DR   Q57S24, FOLD_SALCH ;  B5FLQ2, FOLD_SALDC ;  B5QUV5, FOLD_SALEP ;
DR   B5R6X5, FOLD_SALG2 ;  B4TA94, FOLD_SALHS ;  B4SXP7, FOLD_SALNS ;
DR   Q5PCE5, FOLD_SALPA ;  A9MW26, FOLD_SALPB ;  C0PVJ3, FOLD_SALPC ;
DR   B5BCZ5, FOLD_SALPK ;  Q2S1I0, FOLD_SALRD ;  B4TN64, FOLD_SALSV ;
DR   Q60006, FOLD_SALTI ;  P58688, FOLD_SALTY ;  A8GAY2, FOLD_SERP5 ;
DR   A1S4X3, FOLD_SHEAM ;  B8E5F1, FOLD_SHEB2 ;  A3D303, FOLD_SHEB5 ;
DR   A6WLP9, FOLD_SHEB8 ;  A9KWH5, FOLD_SHEB9 ;  Q12L99, FOLD_SHEDO ;
DR   Q07ZX6, FOLD_SHEFN ;  B0TLV1, FOLD_SHEHH ;  A3QFX8, FOLD_SHELP ;
DR   Q8EG21, FOLD_SHEON ;  A8H616, FOLD_SHEPA ;  A4Y5I0, FOLD_SHEPC ;
DR   B8CRF9, FOLD_SHEPW ;  A0KYM1, FOLD_SHESA ;  A8FTH7, FOLD_SHESH ;
DR   Q0HH99, FOLD_SHESM ;  Q0HTK5, FOLD_SHESR ;  A1RL91, FOLD_SHESW ;
DR   B1KLT9, FOLD_SHEWM ;  B2TTB0, FOLD_SHIB3 ;  Q324Y6, FOLD_SHIBS ;
DR   Q32JK7, FOLD_SHIDS ;  Q0T773, FOLD_SHIF8 ;  Q83SC8, FOLD_SHIFL ;
DR   Q3Z4P8, FOLD_SHISS ;  Q1GE28, FOLD_SILST ;  Q2NV44, FOLD_SODGM ;
DR   Q01X76, FOLD_SOLUE ;  A9GW22, FOLD_SORC5 ;  Q1GNH1, FOLD_SPHAL ;
DR   Q8KN38, FOLD_SPHCR ;  Q14NV1, FOLD_SPICI ;  A7X0V3, FOLD_STAA1 ;
DR   A6U0N1, FOLD_STAA2 ;  Q2FI15, FOLD_STAA3 ;  Q2FZJ6, FOLD_STAA8 ;
DR   A5IRV0, FOLD_STAA9 ;  Q2YX11, FOLD_STAAB ;  Q5HH21, FOLD_STAAC ;
DR   A6QFS2, FOLD_STAAE ;  Q99V34, FOLD_STAAM ;  Q7A697, FOLD_STAAN ;
DR   Q6GI21, FOLD_STAAR ;  Q6GAF0, FOLD_STAAS ;  A8Z1K5, FOLD_STAAT ;
DR   Q8NX95, FOLD_STAAW ;  B9DQ45, FOLD_STACT ;  Q5HQA7, FOLD_STAEQ ;
DR   Q8CPP4, FOLD_STAES ;  Q4L572, FOLD_STAHJ ;  Q49WI7, FOLD_STAS1 ;
DR   Q3K2M6, FOLD_STRA1 ;  Q8E6M3, FOLD_STRA3 ;  Q8E168, FOLD_STRA5 ;
DR   Q9K3J6, FOLD_STRCO ;  C0M7V0, FOLD_STRE4 ;  B4U1W4, FOLD_STREM ;
DR   A8AW32, FOLD_STRGC ;  B1W3N7, FOLD_STRGG ;  Q8DVC1, FOLD_STRMU ;
DR   Q99YX2, FOLD_STRP1 ;  Q04L84, FOLD_STRP2 ;  P0DF88, FOLD_STRP3 ;
DR   Q5XB24, FOLD_STRP6 ;  Q7CN13, FOLD_STRP8 ;  Q1JAV4, FOLD_STRPB ;
DR   Q1JL04, FOLD_STRPC ;  Q1JG29, FOLD_STRPD ;  Q1J5U5, FOLD_STRPF ;
DR   A2RDM9, FOLD_STRPG ;  Q48SM7, FOLD_STRPM ;  Q97RI9, FOLD_STRPN ;
DR   P0DF89, FOLD_STRPQ ;  B5XM84, FOLD_STRPZ ;  Q8DQD3, FOLD_STRR6 ;
DR   A4VZV9, FOLD_STRS2 ;  C0MD36, FOLD_STRS7 ;  A3CLQ4, FOLD_STRSV ;
DR   A4VTM4, FOLD_STRSY ;  Q5M0P7, FOLD_STRT1 ;  Q5M583, FOLD_STRT2 ;
DR   Q03LK0, FOLD_STRTD ;  P96050, FOLD_STRTR ;  B9DUU0, FOLD_STRU0 ;
DR   Q30RJ0, FOLD_SULDN ;  A6Q815, FOLD_SULNB ;  B2V9R3, FOLD_SULSY ;
DR   Q67NB1, FOLD_SYMTH ;  Q2LUP9, FOLD_SYNAS ;  Q31Q60, FOLD_SYNE7 ;
DR   A0LLR2, FOLD_SYNFM ;  Q2JT84, FOLD_SYNJA ;  Q2JQ25, FOLD_SYNJB ;
DR   Q5N421, FOLD_SYNP6 ;  A5GM31, FOLD_SYNPW ;  Q7TTW4, FOLD_SYNPX ;
DR   A5GRZ3, FOLD_SYNR3 ;  Q0IBG9, FOLD_SYNS3 ;  Q3AYX2, FOLD_SYNS9 ;
DR   Q3AIB3, FOLD_SYNSC ;  Q55626, FOLD_SYNY3 ;  C5BI30, FOLD_TERTT ;
DR   B7IF42, FOLD_THEAB ;  Q05213, FOLD_THEAC ;  Q8DMU0, FOLD_THEEB ;
DR   Q47LR8, FOLD_THEFY ;  A8F7D6, FOLD_THELT ;  A6LP88, FOLD_THEM4 ;
DR   Q9X288, FOLD_THEMA ;  B1YBM2, FOLD_THENV ;  A5ILJ9, FOLD_THEP1 ;
DR   B9KZ23, FOLD_THERP ;  B1LAQ6, FOLD_THESQ ;  Q72JL7, FOLD_THET2 ;
DR   Q5SJ94, FOLD_THET8 ;  Q8RAD0, FOLD_THETN ;  Q979W3, FOLD_THEVO ;
DR   B5YJV1, FOLD_THEYD ;  Q3SKX9, FOLD_THIDA ;  B8GNT6, FOLD_THISH ;
DR   C4LG01, FOLD_TOLAT ;  Q73RS2, FOLD_TREDE ;  O83714, FOLD_TREPA ;
DR   B2S3X1, FOLD_TREPS ;  Q10X46, FOLD_TRIEI ;  Q83HF0, FOLD_TROW8 ;
DR   Q83FS2, FOLD_TROWT ;  C5CXD8, FOLD_VARPS ;  A1WJ68, FOLD_VEREI ;
DR   A5CVZ6, FOLD_VESOH ;  A5F6V4, FOLD_VIBC3 ;  Q9KQQ6, FOLD_VIBCH ;
DR   Q5E3Y1, FOLD_VIBF1 ;  B5FG69, FOLD_VIBFM ;  A7MT09, FOLD_VIBHB ;
DR   Q87RB8, FOLD_VIBPA ;  B7VL71, FOLD_VIBSL ;  Q8DB06, FOLD_VIBVU ;
DR   Q7MIX2, FOLD_VIBVY ;  Q8D2W0, FOLD_WIGBR ;  Q73HK3, FOLD_WOLPM ;
DR   B3CLT4, FOLD_WOLPP ;  Q7M8X1, FOLD_WOLSU ;  Q5GTK9, FOLD_WOLTR ;
DR   C0R2N7, FOLD_WOLWR ;  Q8PK86, FOLD_XANAC ;  Q3BSP5, FOLD_XANC5 ;
DR   Q4UVC7, FOLD_XANC8 ;  B0RSB3, FOLD_XANCB ;  Q8P8Q4, FOLD_XANCP ;
DR   Q2P3R1, FOLD_XANOM ;  B2SLG3, FOLD_XANOP ;  Q5H0S4, FOLD_XANOR ;
DR   Q9PAR4, FOLD_XYLFA ;  Q87BK4, FOLD_XYLFT ;  A1JNX2, FOLD_YERE8 ;
DR   A7FL44, FOLD_YERP3 ;  Q1C4U4, FOLD_YERPA ;  B2K7N4, FOLD_YERPB ;
DR   Q7CJY7, FOLD_YERPE ;  A9R256, FOLD_YERPG ;  Q1CKX8, FOLD_YERPN ;
DR   A4TP60, FOLD_YERPP ;  Q66DK7, FOLD_YERPS ;  B1JHI9, FOLD_YERPY ;
DR   Q5NP22, FOLD_ZYMMO ;  P55818, MTDA_METEA ;
//
ID   1.5.1.6
DE   Formyltetrahydrofolate dehydrogenase.
AN   10-formyltetrahydrofolate dehydrogenase.
CA   10-formyltetrahydrofolate + NADP(+) + H(2)O = tetrahydrofolate + CO(2) +
CA   NADPH.
PR   PROSITE; PDOC00068;
DR   O75891, AL1L1_HUMAN;  Q8R0Y6, AL1L1_MOUSE;  Q5RFM9, AL1L1_PONAB;
DR   P28037, AL1L1_RAT  ;  Q6GNL7, AL1L1_XENLA;  Q63ZT8, AL1L1_XENTR;
DR   Q3SY69, AL1L2_HUMAN;  Q8K009, AL1L2_MOUSE;
//
ID   1.5.1.7
DE   Saccharopine dehydrogenase (NAD(+), L-lysine-forming).
AN   Lysine-2-oxoglutarate reductase.
CA   N(6)-(L-1,3-dicarboxypropyl)-L-lysine + NAD(+) + H(2)O = L-lysine +
CA   2-oxoglutarate + NADH.
DR   Q75BV4, LYS1_ASHGO ;  P43065, LYS1_CANAL ;  Q6FU27, LYS1_CANGA ;
DR   Q870G1, LYS1_EMENI ;  Q7SFX6, LYS1_NEUCR ;  Q09694, LYS1_SCHPO ;
DR   P38997, LYS1_YARLI ;  P38998, LYS1_YEAST ;
//
ID   1.5.1.8
DE   Saccharopine dehydrogenase (NADP(+), L-lysine-forming).
AN   Lysine-2-oxoglutarate reductase.
AN   Lysine-ketoglutarate reductase.
CA   N(6)-(L-1,3-dicarboxypropyl)-L-lysine + NADP(+) + H(2)O = L-lysine +
CA   2-oxoglutarate + NADPH.
DR   Q9SMZ4, AASS_ARATH ;  A8E657, AASS_BOVIN ;  Q9UDR5, AASS_HUMAN ;
DR   Q99K67, AASS_MOUSE ;  A2VCW9, AASS_RAT   ;
//
ID   1.5.1.9
DE   Saccharopine dehydrogenase (NAD(+), L-glutamate-forming).
AN   Aminoadipic semialdehyde synthase.
AN   Saccharopin dehydrogenase.
CA   N(6)-(L-1,3-dicarboxypropyl)-L-lysine + NAD(+) + H(2)O = L-glutamate +
CA   (S)-2-amino-6-oxohexanoate + NADH.
DR   Q9SMZ4, AASS_ARATH ;  A8E657, AASS_BOVIN ;  Q9UDR5, AASS_HUMAN ;
DR   Q99K67, AASS_MOUSE ;  A2VCW9, AASS_RAT   ;  Q8LGI2, SCPDH_ARATH;
DR   Q3T067, SCPDH_BOVIN;  Q8NBX0, SCPDH_HUMAN;  Q8R127, SCPDH_MOUSE;
DR   Q5R5C9, SCPDH_PONAB;  Q6AY30, SCPDH_RAT  ;
//
ID   1.5.1.10
DE   Saccharopine dehydrogenase (NADP(+), L-glutamate-forming).
AN   Aminoadipate semialdehyde-glutamate reductase.
AN   Aminoadipic semialdehyde-glutamate reductase.
AN   Aminoadipic semialdehyde-glutamic reductase.
AN   Saccharopine reductase.
CA   N(6)-(L-1,3-dicarboxypropyl)-L-lysine + NADP(+) + H(2)O = L-glutamate +
CA   (S)-2-amino-6-oxohexanoate + NADPH.
DR   Q9P4R4, LYS9_MAGO7 ;  O59711, LYS9_SCHPO ;  P38999, LYS9_YEAST ;
DR   Q54NG9, SCPDH_DICDI;
//
ID   1.5.1.11
DE   D-octopine dehydrogenase.
AN   D-octopine synthase.
AN   Octopine dehydrogenase.
AN   ODH.
CA   N(2)-(D-1-carboxyethyl)-L-arginine + NAD(+) + H(2)O = L-arginine +
CA   pyruvate + NADH.
CC   -!- Also acts, in the reverse direction, on L-ornithine, L-lysine and
CC       L-histidine.
DR   P0A394, DHLO_AGRT4 ;  P0A395, DHLO_AGRT9 ;  P94210, DHLO_AGRVI ;
//
ID   1.5.1.12
DE   1-pyrroline-5-carboxylate dehydrogenase.
CA   (S)-1-pyrroline-5-carboxylate + NAD(P)(+) + 2 H(2)O = L-glutamate +
CA   NAD(P)H.
CC   -!- Oxidizes a number of 1-pyrrolines, e.g. 3-hydroxy-1-pyrroline-5-
CC       carboxylate is converted into 4-hydroxyglutamate and (R)-1-pyrroline-
CC       5-carboxylate is converted into D-glutamate.
CC   -!- While NAD(+) appears to be the better electron acceptor, NADP(+) can
CC       also act, but more slowly.
CC   -!- In many organisms, ranging from bacteria to mammals, proline is
CC       oxidized to glutamate in a two-step process involving this enzyme and
CC       EC 1.5.99.8.
CC   -!- In many bacterial species, both activities are carried out by a
CC       single bifunctional enzyme.
PR   PROSITE; PDOC00068;
DR   Q8VZC3, AL121_ARATH;  A7YWE4, AL4A1_BOVIN;  Q7SY23, AL4A1_DANRE;
DR   Q54RA2, AL4A1_DICDI;  P30038, AL4A1_HUMAN;  Q8CHT0, AL4A1_MOUSE;
DR   P0C2X9, AL4A1_RAT  ;  P78568, PUT2_AGABI ;  Q9P8I0, PUT2_EMENI ;
DR   O74766, PUT2_SCHPO ;  P07275, PUT2_YEAST ;  P09546, PUTA_ECOLI ;
DR   O52485, PUTA_ENTAE ;  P23725, PUTA_KLEPN ;  P95629, PUTA_RHIME ;
DR   P10503, PUTA_SALTY ;  Q9K9B2, ROCA1_BACHD;  Q9K5Z5, ROCA2_BACHD;
DR   P94391, ROCA2_BACSU;  B7GFV3, ROCA_ANOFW ;  C3PBP4, ROCA_BACAA ;
DR   C3L546, ROCA_BACAC ;  A0R909, ROCA_BACAH ;  Q81ZF8, ROCA_BACAN ;
DR   B7JM99, ROCA_BACC0 ;  P62028, ROCA_BACC1 ;  B7IUW8, ROCA_BACC2 ;
DR   C1EV77, ROCA_BACC3 ;  B7H4V1, ROCA_BACC4 ;  B7HSW8, ROCA_BACC7 ;
DR   A7GKJ4, ROCA_BACCN ;  B9J1L9, ROCA_BACCQ ;  Q81IP0, ROCA_BACCR ;
DR   Q63GS0, ROCA_BACCZ ;  Q6HP91, ROCA_BACHK ;  Q65NN2, ROCA_BACLD ;
DR   A8F9T1, ROCA_BACP2 ;  P39634, ROCA_BACSU ;  A9VRG6, ROCA_BACWK ;
DR   Q5L3K8, ROCA_GEOKA ;  C5D4J5, ROCA_GEOSW ;  A4IJP9, ROCA_GEOTN ;
DR   Q8ERF4, ROCA_OCEIH ;  A7X6R7, ROCA_STAA1 ;  A6U4T5, ROCA_STAA2 ;
DR   Q2FDV3, ROCA_STAA3 ;  Q2FV67, ROCA_STAA8 ;  A5IVY0, ROCA_STAA9 ;
DR   Q2YWA6, ROCA_STAAB ;  Q5HCZ6, ROCA_STAAC ;  A6QK44, ROCA_STAAE ;
DR   P63939, ROCA_STAAM ;  P99076, ROCA_STAAN ;  Q6GDP4, ROCA_STAAR ;
DR   Q6G6C0, ROCA_STAAS ;  A8Z3F5, ROCA_STAAT ;  Q8NUR2, ROCA_STAAW ;
DR   Q5HL59, ROCA_STAEQ ;  Q8CN04, ROCA_STAES ;  Q4L966, ROCA_STAHJ ;
DR   Q4A0E7, ROCA_STAS1 ;
//
ID   1.5.1.13
DE   Transferred entry: 1.17.1.5.
//
ID   1.5.1.14
DE   Transferred entry: 1.5.1.21.
//
ID   1.5.1.15
DE   Methylenetetrahydrofolate dehydrogenase (NAD(+)).
CA   5,10-methylenetetrahydrofolate + NAD(+) = 5,10-methenyltetrahydrofolate +
CA   NADH.
PR   PROSITE; PDOC00616;
DR   Q86KU6, MTD1_DICDI ;  Q9P786, MTD1_SCHPO ;  Q02046, MTD1_YEAST ;
DR   Q9H903, MTD2L_HUMAN;  Q0P5C2, MTDC_BOVIN ;  Q5ZKA5, MTDC_CHICK ;
DR   Q04448, MTDC_DROME ;  P13995, MTDC_HUMAN ;  P18155, MTDC_MOUSE ;
//
ID   1.5.1.16
DE   D-lysopine dehydrogenase.
AN   D-lysopine synthase.
AN   Lysopine dehydrogenase.
CA   N(2)-(D-1-carboxyethyl)-L-lysine + NADP(+) + H(2)O = L-lysine + pyruvate
CA   + NADPH.
CC   -!- In the reverse reaction, a number of L-amino acids can act instead of
CC       L-lysine, and 2-oxobutanoate and, to a lesser extent, glyoxylate can
CC       act instead of pyruvate.
DR   P0A394, DHLO_AGRT4 ;  P0A395, DHLO_AGRT9 ;  P94210, DHLO_AGRVI ;
//
ID   1.5.1.17
DE   Alanopine dehydrogenase.
CA   2,2'-iminodipropanoate + NAD(+) + H(2)O = L-alanine + pyruvate + NADH.
CC   -!- In the reverse reaction, L-alanine can be replaced by L-cysteine,
CC       L-serine, or L-threonine; glycine acts very slowly (cf. EC 1.5.1.22).
//
ID   1.5.1.18
DE   Ephedrine dehydrogenase.
CA   (-)-ephedrine + NAD(+) = (R)-2-methylimino-1-phenylpropan-1-ol + NADH.
CC   -!- The product immediately hydrolyzes to methylamine and 1-hydroxy-1-
CC       phenylpropan-2-one.
CC   -!- Acts on a number of related compounds including (-)-sympatol, (+)-
CC       pseudoephedrine and (+)-norephedrine.
//
ID   1.5.1.19
DE   D-nopaline dehydrogenase.
AN   D-nopaline synthase.
AN   Nopaline dehydrogenase.
AN   Nopaline synthase.
AN   NOS.
CA   N(2)-(D-1,3-dicarboxypropyl)-L-arginine + NADP(+) + H(2)O = L-arginine +
CA   2-oxoglutarate + NADPH.
CC   -!- In the reverse direction, forms D-nopaline from L-arginine and
CC       D-ornaline from L-ornithine.
DR   P00386, DHNO_AGRT7 ;  Q44524, DHNO_AGRVI ;
//
ID   1.5.1.20
DE   Methylenetetrahydrofolate reductase (NAD(P)H).
AN   5,10-CH(2)-H(4)folate reductase.
AN   5,10-methylenetetrahydrofolate reductase.
AN   5,10-methylenetetrahydrofolate reductase (FADH(2)).
AN   5,10-methylenetetrahydrofolate reductase (NADPH).
AN   5,10-methylenetetrahydrofolic acid reductase.
AN   5,10-methylenetetrahydropteroylglutamate reductase.
AN   5-methyltetrahydrofolate:(acceptor) oxidoreductase.
AN   5-methyltetrahydrofolate:NAD oxidoreductase.
AN   5-methyltetrahydrofolate:NAD(+) oxidoreductase.
AN   5-methyltetrahydrofolate:NADP(+) oxidoreductase.
AN   Methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide
AN   phosphate) reductase.
AN   Methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide)
AN   reductase.
AN   Methylenetetrahydrofolate reductase.
AN   Methylenetetrahydrofolate reductase (NADPH(2)).
AN   Methylenetetrahydrofolate reductase (NADPH).
AN   Methylenetetrahydrofolic acid reductase.
AN   MTHFR.
AN   N(5),N(10)-methylenetetrahydrofolate reductase.
AN   N(5,10)-methylenetetrahydrofolate reductase.
CA   5-methyltetrahydrofolate + NAD(P)(+) = 5,10-methylenetetrahydrofolate +
CA   NAD(P)H.
CF   FAD.
CC   -!- Menadione can also serve as an electron acceptor.
CC   -!- Formerly EC 1.1.1.68, EC 1.1.1.171, EC 1.1.99.15 and EC 1.7.99.5.
DR   O67422, METF_AQUAE ;  P57154, METF_BUCAI ;  Q8KA62, METF_BUCAP ;
DR   Q89B13, METF_BUCBP ;  P0AEZ1, METF_ECOLI ;  P45208, METF_HAEIN ;
DR   Q9JZQ3, METF_NEIMB ;  P71319, METF_PECCC ;  P11003, METF_SALTY ;
DR   P0AEZ2, METF_SHIFL ;  O54235, METF_STRLI ;  Q9SE60, MTHR1_ARATH;
DR   Q9SE94, MTHR1_MAIZE;  Q10258, MTHR1_SCHPO;  P46151, MTHR1_YEAST;
DR   O80585, MTHR2_ARATH;  O74927, MTHR2_SCHPO;  P53128, MTHR2_YEAST;
DR   Q5I598, MTHR_BOVIN ;  Q17693, MTHR_CAEEL ;  P42898, MTHR_HUMAN ;
DR   Q60HE5, MTHR_MACFA ;  Q9WU20, MTHR_MOUSE ;  Q75HE6, MTHR_ORYSJ ;
DR   O06745, YITJ_BACSU ;
//
ID   1.5.1.21
DE   Delta(1)-piperideine-2-carboxylate reductase.
CA   L-pipecolate + NADP(+) = Delta(1)-piperideine-2-carboxylate + NADPH.
CC   -!- Formerly EC 1.5.1.14.
//
ID   1.5.1.22
DE   Strombine dehydrogenase.
CA   N-(carboxymethyl)-D-alanine + NAD(+) + H(2)O = glycine + pyruvate + NADH.
CC   -!- Catalyzes the reaction of EC 1.5.1.17, more slowly.
CC   -!- Does not act on L-strombine.
//
ID   1.5.1.23
DE   Tauropine dehydrogenase.
CA   Tauropine + NAD(+) + H(2)O = taurine + pyruvate + NADH.
CC   -!- In the reverse reaction, alanine can act instead of taurine, more
CC       slowly, and 2-oxobutanoate and 2-oxopentanoate can act instead of
CC       pyruvate.
//
ID   1.5.1.24
DE   N(5)-(carboxyethyl)ornithine synthase.
CA   N(5)-(L-1-carboxyethyl)-L-ornithine + NADP(+) + H(2)O = L-ornithine +
CA   pyruvate + NADPH.
CC   -!- In the reverse direction L-lysine can act instead of L-ornithine,
CC       more slowly.
CC   -!- Acts on the amino group (cf. EC 1.5.1.16).
DR   Q9CG73, CEO1_LACLA ;  P15244, CEO2_LACLA ;  A5HZ59, CEO_CLOBH  ;
//
ID   1.5.1.25
DE   Thiomorpholine-carboxylate dehydrogenase.
AN   Ketimine reductase.
CA   Thiomorpholine 3-carboxylate + NAD(P)(+) = 3,4-dehydro-thiomorpholine-3-
CA   carboxylate + NAD(P)H.
CC   -!- The product is the cyclic imine of the 2-oxoacid corresponding to
CC       S-(2-aminoethyl)cysteine.
CC   -!- In the reverse direction, a number of other cyclic unsaturated
CC       compounds can act as substrates, more slowly.
//
ID   1.5.1.26
DE   Beta-alanopine dehydrogenase.
CA   Beta-alanopine + NAD(+) + H(2)O = beta-alanine + pyruvate + NADH.
//
ID   1.5.1.27
DE   1,2-dehydroreticulinium reductase (NADPH).
AN   1,2-dehydroreticulinium ion reductase.
CA   (R)-reticuline + NADP(+) = 1,2-dehydroreticulinium + NADPH.
CC   -!- Reduces the 1,2-dehydroreticulinium ion to (R)-reticuline, which is a
CC       direct precursor of morphinan alkaloids in the poppy plant.
CC   -!- The enzyme does not catalyze the reverse reaction to any significant
CC       extent under physiological conditions.
//
ID   1.5.1.28
DE   Opine dehydrogenase.
CA   (2S)-2-((1-(R)-carboxyethyl)amino)pentanoate + NAD(+) + H(2)O = L-2-
CA   aminopentanoic acid + pyruvate + NADH.
CC   -!- In the forward direction, the enzyme from Arthrobacter sp. acts also
CC       on secondary amine dicarboxylates such as
CC       N-(1-carboxyethyl)methionine and N-(1-carboxyethyl)phenylalanine.
CC   -!- Dehydrogenation forms an imine, which dissociates to the amino acid
CC       and pyruvate.
CC   -!- In the reverse direction, the enzyme acts also on neutral amino acids
CC       as an amino donor.
CC   -!- They include L-amino acids such as 2-aminopentanoic acid,
CC       2-aminobutyric acid, 2-aminohexanoic acid, 3-chloroalanine,
CC       O-acetylserine, methionine, isoleucine, valine, phenylalanine,
CC       leucine and alanine.
CC   -!- The amino acceptors include 2-oxoacids such as pyruvate,
CC       oxaloacetate, glyoxylate and 2-oxobutyrate.
DR   Q44297, ODH_ARTSC  ;
//
ID   1.5.1.29
DE   FMN reductase.
AN   Flavin mononucleotide reductase.
AN   Flavine mononucleotide reductase.
AN   NAD(P)H dehydrogenase (FMN).
AN   NAD(P)H(2) dehydrogenase (FMN).
AN   NAD(P)H(2):FMN oxidoreductase.
AN   NAD(P)H-dependent FMN reductase.
AN   NAD(P)H-FMN reductase.
AN   NAD(P)H:flavin oxidoreductase.
AN   NAD(P)H:FMN oxidoreductase.
AN   Riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide
AN   (phosphate)) reductase.
AN   Riboflavin mononucleotide reductase.
AN   Riboflavine mononucleotide reductase.
CA   FMNH(2) + NAD(P)(+) = FMN + NAD(P)H.
CC   -!- The enzyme from luminescent bacteria and the SsuE enzyme from
CC       Escherichia coli also reduce riboflavin and FAD, but more slowly.
CC   -!- In E.coli, this enzyme, in conjunction with EC 1.14.14.5, forms a
CC       two-component alkanesulfonate monooxygenase, which allows for
CC       utilization of alkanesulfonates as sulfur sources under conditions of
CC       sulfate and cysteine starvation.
CC   -!- Formerly EC 1.6.8.1.
DR   Q9USJ6, FMNR_SCHPO ;  P0AEN3, FRE_ECO57  ;  P0AEN2, FRE_ECOL6  ;
DR   P0AEN1, FRE_ECOLI  ;  Q9L6L9, FRE_SALTY  ;  Q07923, LOT6_YEAST ;
DR   O31038, MSUE_PSEAE ;  Q88J85, MSUE_PSEPK ;  P39605, NFRA1_BACSU;
DR   P94424, NFRA2_BACSU;  B9J8R4, RUTF1_AGRRK;  B7KWT3, RUTF1_METC4;
DR   A9W3H7, RUTF1_METEP;  B9JLT5, RUTF2_AGRRK;  B7KT53, RUTF2_METC4;
DR   A9W6X8, RUTF2_METEP;  Q6FFZ4, RUTF_ACIAD ;  A9CHR3, RUTF_AGRT5 ;
DR   Q89Q06, RUTF_BRAJA ;  C9Y0S2, RUTF_CROTZ ;  C8U5G9, RUTF_ECO10 ;
DR   C8UMM3, RUTF_ECO1A ;  A7ZKB2, RUTF_ECO24 ;  C8TNB7, RUTF_ECO26 ;
DR   B7UNZ0, RUTF_ECO27 ;  D3H120, RUTF_ECO44 ;  B7MIF4, RUTF_ECO45 ;
DR   B7LFB7, RUTF_ECO55 ;  Q8XAV0, RUTF_ECO57 ;  B5YU49, RUTF_ECO5E ;
DR   C6UPM9, RUTF_ECO5T ;  B7NLB9, RUTF_ECO7I ;  B7MQ18, RUTF_ECO81 ;
DR   B7M8Z2, RUTF_ECO8A ;  C6EHK0, RUTF_ECOBD ;  C6UFB8, RUTF_ECOBR ;
DR   C4ZQD5, RUTF_ECOBW ;  D3QPK0, RUTF_ECOCB ;  C9QZ69, RUTF_ECOD1 ;
DR   B1X9C8, RUTF_ECODH ;  A7ZYW2, RUTF_ECOHS ;  A1A9R2, RUTF_ECOK1 ;
DR   D5CZG7, RUTF_ECOKI ;  Q0TJ60, RUTF_ECOL5 ;  Q8FJ45, RUTF_ECOL6 ;
DR   B1IV90, RUTF_ECOLC ;  P75893, RUTF_ECOLI ;  B7N3G3, RUTF_ECOLU ;
DR   D2NGI4, RUTF_ECOS5 ;  B6I983, RUTF_ECOSE ;  B1LIZ8, RUTF_ECOSM ;
DR   Q1RDL0, RUTF_ECOUT ;  A4W920, RUTF_ENT38 ;  D5CE37, RUTF_ENTCC ;
DR   A7MFX8, RUTF_ENTS8 ;  B5XXN5, RUTF_KLEP3 ;  A6T797, RUTF_KLEP7 ;
DR   D3RKL5, RUTF_KLEVT ;  C5B0U5, RUTF_METEA ;  C7CM32, RUTF_METED ;
DR   B1ZB19, RUTF_METPB ;  D4GEU9, RUTF_PANAM ;  Q48MQ8, RUTF_PSE14 ;
DR   Q4ZXS1, RUTF_PSEU2 ;  A4VQH9, RUTF_PSEU5 ;  A8GCT2, RUTF_SERP5 ;
DR   Q32HQ4, RUTF_SHIDS ;  D2AC38, RUTF_SHIF2 ;  Q0T627, RUTF_SHIF8 ;
DR   Q83LK9, RUTF_SHIFL ;  Q3Z3A6, RUTF_SHISS ;  D7A989, RUTF_STAND ;
DR   C5CN84, RUTF_VARPS ;  A1JMW4, RUTF_YERE8 ;  P80644, SSUE_ECOLI ;
DR   Q88R97, SSUE_PSEPK ;  O85762, SSUE_PSEPU ;
//
ID   1.5.1.30
DE   Flavin reductase.
AN   Flavin mononucleotide reductase.
AN   Flavine mononucleotide reductase.
AN   FMN reductase (NADPH).
AN   NADPH dehydrogenase (flavin).
AN   NADPH-dependent FMN reductase.
AN   NADPH-flavin reductase.
AN   NADPH-FMN reductase.
AN   NADPH-specific FMN reductase.
AN   NADPH:flavin oxidoreductase.
AN   NADPH:riboflavin oxidoreductase.
AN   Riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide
AN   phosphate) reductase.
AN   Riboflavin mononucleotide reductase.
AN   Riboflavine mononucleotide reductase.
CA   Reduced riboflavin + NADP(+) = riboflavin + NADPH.
CC   -!- The enzyme from Entamoeba histolytica reduces riboflavin and
CC       galactoflavin, and, more slowly, FMN and FAD.
CC   -!- NADH is oxidized more slowly than NADPH.
CC   -!- Formerly EC 1.6.8.2.
DR   P52556, BLVRB_BOVIN;  P30043, BLVRB_HUMAN;  Q923D2, BLVRB_MOUSE;
DR   P55736, BLVRB_RANCA;
//
ID   1.5.1.31
DE   Berberine reductase.
AN   (R)-canadine synthase.
CA   (R)-canadine + 2 NADP(+) = berberine + 2 NADPH.
CC   -!- Involved in alkaloid biosynthesis in Corydalis cava to give (R)-
CC       canadine with the opposite configuration to the precursor of
CC       berberine (see EC 1.3.3.8).
CC   -!- Also acts on 7,8-dihydroberberine.
//
ID   1.5.1.32
DE   Vomilenine reductase.
CA   1,2-dihydrovomilenine + NADP(+) = vomilenine + NADPH.
CC   -!- Forms part of the ajmaline biosynthesis pathway.
//
ID   1.5.1.33
DE   Pteridine reductase.
AN   Pteridine reductase 1.
AN   PTR1.
CA   5,6,7,8-tetrahydrobiopterin + 2 NADP(+) = biopterin + 2 NADPH.
CC   -!- The enzyme from Leishmania (both amastigote and promastigote forms)
CC       catalyzes the NADPH-dependent reduction of folate and a wide variety
CC       of unconjugated pterins, including biopterin, to their tetrahydro
CC       forms.
CC   -!- It also catalyzes the reduction of 7,8-dihydropterins and 7,8-
CC       dihydrofolate to their tetrahydro forms.
CC   -!- In contrast to EC 1.5.1.3 and EC 1.5.1.34, pteridine reductase will
CC       not catalyze the reduction of the quinonoid form of dihydrobiopterin.
CC   -!- The enzyme is specific for NADPH; no activity has been detected with
CC       NADH.
CC   -!- It also differs from EC 1.5.1.3 in being specific for the B side of
CC       NADPH.
CC   -!- Formerly EC 1.1.1.253.
PR   PROSITE; PDOC00060;
DR   Q01782, PTR1_LEIMA ;  P42556, PTR1_LEITA ;
//
ID   1.5.1.34
DE   6,7-dihydropteridine reductase.
AN   6,7-dihydropteridine:NAD(P)H oxidoreductase.
AN   DHPR.
AN   Dihydropteridine (reduced nicotinamide adenine dinucleotide) reductase.
AN   Dihydropteridine reductase.
AN   Dihydropteridine reductase (NADH).
AN   NAD(P)H(2):6,7-dihydropteridine oxidoreductase.
AN   NADH-dihydropteridine reductase.
AN   NADPH-dihydropteridine reductase.
AN   NADPH-specific dihydropteridine reductase.
CA   A 5,6,7,8-tetrahydropteridine + NAD(P)(+) = a 6,7-dihydropteridine +
CA   NAD(P)H.
CC   -!- The substrate is the quinonoid form of dihydropteridine.
CC   -!- Not identical with EC 1.5.1.3.
CC   -!- Formerly EC 1.6.99.7 and EC 1.6.99.10.
PR   PROSITE; PDOC00060;
DR   Q3T0Z7, DHPR_BOVIN ;  Q86A17, DHPR_DICDI ;  P09417, DHPR_HUMAN ;
DR   Q8BVI4, DHPR_MOUSE ;  Q8MJ30, DHPR_PIG   ;  P11348, DHPR_RAT   ;
DR   P38489, NFNB_ECOLI ;
//
ID   1.5.1.35
DE   Transferred entry: 1.2.1.19.
//
ID   1.5.3.1
DE   Sarcosine oxidase.
CA   Sarcosine + H(2)O + O(2) = glycine + formaldehyde + H(2)O(2).
CF   FAD.
CC   -!- The flavin is both covalently and non-covalently bound in a molar
CC       ratio of 1:1.
DR   P40873, MSOX_ARTST ;  P40859, MSOX_BACB0 ;  P23342, MSOX_BACSN ;
DR   Q827H4, MSOX_STRAW ;  P40854, MSOX_STRSB ;  Q46337, SOXA_CORS1 ;
DR   O87386, SOXA_RHIME ;  P40875, SOXB_CORS1 ;  O87388, SOXB_RHIME ;
DR   Q52671, SOXB_RHOCB ;  Q46336, SOXD_CORS1 ;  O87387, SOXD_RHIME ;
DR   Q46338, SOXG_CORS1 ;  Q9SJA7, SOX_ARATH  ;  Q29RU9, SOX_BOVIN  ;
DR   Q18006, SOX_CAEEL  ;  Q9P0Z9, SOX_HUMAN  ;  Q9D826, SOX_MOUSE  ;
DR   P79371, SOX_RABIT  ;  Q54EW2, Y9130_DICDI;
//
ID   1.5.3.2
DE   N-methyl-L-amino-acid oxidase.
CA   An N-methyl-L-amino acid + H(2)O + O(2) = an L-amino acid + formaldehyde
CA   + H(2)O(2).
CF   Flavoprotein.
//
ID   1.5.3.3
DE   Deleted entry.
//
ID   1.5.3.4
DE   N(6)-methyl-lysine oxidase.
AN   Epsilon-alkyllysinase.
AN   Epsilon-N-methyllysine demethylase.
AN   N(6)-methyllysine oxidase.
CA   N(6)-methyl-L-lysine + H(2)O + O(2) = L-lysine + formaldehyde + H(2)O(2).
//
ID   1.5.3.5
DE   (S)-6-hydroxynicotine oxidase.
CA   (S)-6-hydroxynicotine + H(2)O + O(2) = 1-(6-hydroxypyridin-3-yl)-4-
CA   (methylamino)butan-1-one + H(2)O(2).
CF   FAD.
//
ID   1.5.3.6
DE   (R)-6-hydroxynicotine oxidase.
CA   (R)-6-hydroxynicotine + H(2)O + O(2) = 1-(6-hydroxypyridin-3-yl)-4-
CA   (methylamino)butan-1-one + H(2)O(2).
CF   FAD.
PR   PROSITE; PDOC00674;
DR   P08159, HDNO_ARTOX ;
//
ID   1.5.3.7
DE   L-pipecolate oxidase.
CA   L-pipecolate + O(2) = (S)-2,3,4,5-tetrahydropyridine-2-carboxylate +
CA   H(2)O(2).
CC   -!- The product reacts with water to form (S)-2-amino-6-oxohexanoate.
DR   O43029, FAP1_SCHPO ;  Q29RU9, SOX_BOVIN  ;  Q9P0Z9, SOX_HUMAN  ;
DR   Q9D826, SOX_MOUSE  ;  P79371, SOX_RABIT  ;  Q54EW2, Y9130_DICDI;
//
ID   1.5.3.8
DE   Transferred entry: 1.3.3.8.
//
ID   1.5.3.9
DE   Transferred entry: 1.21.3.3.
//
ID   1.5.3.10
DE   Dimethylglycine oxidase.
CA   N,N-dimethylglycine + H(2)O + O(2) = sarcosine + formaldehyde + H(2)O(2).
CF   FAD.
CC   -!- Does not oxidize sarcosine.
//
ID   1.5.3.11
DE   Transferred entry: 1.5.3.13, 1.5.3.14, 1.5.3.15, 1.5.3.16 and 1.5.3.17.
//
ID   1.5.3.12
DE   Dihydrobenzophenanthridine oxidase.
CA   (1) Dihydrosanguinarine + O(2) = sanguinarine + H(2)O(2).
CA   (2) Dihydrochelirubine + O(2) = chelirubine + H(2)O(2).
CA   (3) Dihydromacarpine + O(2) = macarpine + H(2)O(2).
CF   Copper.
CC   -!- Found in higher plants.
CC   -!- Produces oxidized forms of the benzophenanthridine alkaloids.
//
ID   1.5.3.13
DE   N(1)-acetylpolyamine oxidase.
AN   PAO.
AN   Polyamine oxidase.
CA   (1) N(1)-acetylspermidine + O(2) + H(2)O = putrescine +
CA   3-acetamidopropanal + H(2)O(2).
CA   (2) N(1)-acetylspermine + O(2) + H(2)O = spermidine + 3-acetamidopropanal
CA   + H(2)O(2).
CF   FAD.
CC   -!- The enzyme also catalyzes the reaction: N(1),N(12)-diacetylspermine +
CC       O(2) + H(2)O = N(1)-acetylspermidine + 3-acetamamidopropanal +
CC       H(2)O(2).
CC   -!- No or very weak activity with spermine, or spermidine in absence of
CC       aldehydes.
CC   -!- In presence of aldehydes the enzyme catalyzes the reactions: 1.
CC   -!- spermine + O(2) + H(2)O = spermidine + 3-aminopropanal + H(2)O(2),
CC       and with weak efficiency 2.
CC   -!- spermidine + O(2) + H(2)O = putrescine + 3-aminopropanal + H(2)O(2).
CC   -!- Found in mammalian peroxisomes and oxidizes N(1)-acetylated
CC       polyamines at the exo (three-carbon) side of the secondary amine,
CC       forming 3-acetamamidopropanal.
CC   -!- Since the products of the reactions are deacetylated polyamines, this
CC       process is known as polyamine back-conversion.
CC   -!- Differs in specificity from EC 1.5.3.14, EC 1.5.3.15, EC 1.5.3.16 and
CC       EC 1.5.3.17.
CC   -!- Formerly EC 1.5.3.11, EC 1.5.3.n3, EC 1.5.3.n4 and EC 1.5.3.n10.
DR   Q865R1, PAOX_BOVIN ;  Q6QHF9, PAOX_HUMAN ;  Q8C0L6, PAOX_MOUSE ;
//
ID   1.5.3.14
DE   Polyamine oxidase (propane-1,3-diamine-forming).
AN   Maize PAO.
AN   MPAO.
CA   Spermidine + O(2) + H(2)O = propane-1,3-diamine + 4-aminobutanal +
CA   H(2)O(2).
CF   FAD.
CC   -!- As the products of the reaction cannot be converted directly to other
CC       polyamines, this class of polyamine oxidases is considered to be
CC       involved in the terminal catabolism of polyamines.
CC   -!- Catalyzes less efficiently the oxidation of N(1)-acetylspermine and
CC       spermine.
CC   -!- Differs in specificity from EC 1.5.3.13, EC 1.5.3.15, EC 1.5.3.16 and
CC       EC 1.5.3.17.
CC   -!- Formerly EC 1.5.3.11, EC 1.5.3.n6, EC 1.5.3.n7, EC 1.5.3.n8 and
CC       EC 1.5.3.n9.
DR   O64411, PAO_MAIZE  ;
//
ID   1.5.3.15
DE   N(8)-acetylspermidine oxidase (propane-1,3-diamine-forming).
CA   N(8)-acetylspermidine + O(2) + H(2)O = propane-1,3-diamine +
CA   4-acetamidobutanal + H(2)O(2).
CF   FAD.
CC   -!- Also active with N(1)-acetylspermine, weak activity with N(1),N(12)-
CC       diacetylspermine.
CC   -!- No activity with diaminopropane, putrescine, cadaverine,
CC       diaminohexane, norspermidine, spermine and spermidine.
CC   -!- Absence of monoamine oxidase (EC 1.4.3.4) activity.
CC   -!- Differs in specificity from EC 1.5.3.13, EC 1.5.3.14, EC 1.5.3.16 and
CC       EC 1.5.3.17.
CC   -!- Formerly EC 1.5.3.11, EC 1.5.3.n6, EC 1.5.3.n7, EC 1.5.3.n8 and
CC       EC 1.5.3.n9.
DR   O64411, PAO_MAIZE  ;
//
ID   1.5.3.16
DE   Spermine oxidase.
AN   SMO.
CA   Spermine + O(2) + H(2)O = spermidine + 3-aminopropanal + H(2)O(2).
CF   FAD.
CC   -!- The enzyme from Arabidopsis thaliana (AtPAO1) oxidizes norspermine to
CC       norspermidine with high efficiency.
CC   -!- The mammalian enzyme, encoded by the SMOX gene, is a cytosolic enzyme
CC       that catalyzes the oxidation of spermine at the exo (three-carbon)
CC       side of the tertiary amine.
CC   -!- No activity with spermidine.
CC   -!- Weak activity with N(1)-acetylspermine.
CC   -!- Differs in specificity from EC 1.5.3.13, EC 1.5.3.14, EC 1.5.3.15 and
CC       EC 1.5.3.17.
CC   -!- Formerly EC 1.5.3.11, 1.5.3.n1, EC 1.5.3.n2, EC 1.5.3.n3 and
CC       EC 1.5.3.n5.
DR   Q9FNA2, PAO1_ARATH ;  Q8H191, PAO4_ARATH ;  Q9NWM0, SMOX_HUMAN ;
DR   Q99K82, SMOX_MOUSE ;
//
ID   1.5.3.17
DE   Non-specific polyamine oxidase.
AN   Polyamine oxidase.
CA   (1) Spermine + O(2) + H(2)O = spermidine + 3-aminopropanal + H(2)O(2).
CA   (2) Spermidine + O(2) + H(2)O = putrescine + 3-aminopropanal + H(2)O(2).
CA   (3) N(1)-acetylspermine + O(2) + H(2)O = spermidine + 3-acetamidopropanal
CA   + H(2)O(2).
CA   (4) N(1)-acetylspermidine + O(2) + H(2)O = putrescine +
CA   3-acetamidopropanal + H(2)O(2).
CF   FAD.
CC   -!- The non-specific polyamine oxidases may differ from each other
CC       considerably.
CC   -!- The enzyme from Saccharomyces cerevisiae shows a rather broad
CC       specificity and also oxidizes N(8)-acetylspermidine.
CC   -!- The enzyme from Ascaris suum shows high activity with spermine and
CC       spermidine, but also oxidizes norspermine.
CC   -!- The enzyme from Arabidopsis thaliana shows high activity with
CC       spermidine, but also oxidizes other polyamines.
CC   -!- The specific polyamine oxidases are classified as EC 1.5.3.13,
CC       EC 1.5.3.14, EC 1.5.3.15 and EC 1.5.3.16.
CC   -!- Formerly EC 1.5.3.11, EC 1.5.3.n1, EC 1.5.3.n2 and EC 1.5.3.n4.
DR   P50264, FMS1_YEAST ;  Q9LYT1, PAO3_ARATH ;
//
ID   1.5.3.18
DE   L-saccharopine oxidase.
AN   FAP2.
CA   L-saccharopine + H(2)O + O(2) = (S)-2-amino-6-oxohexanoate + L-glutamate
CA   + H(2)O(2).
CF   FAD.
CC   -!- The enzyme is involved in pipecolic acid biosynthesis.
DR   Q9UTM9, FAP2_SCHPO ;
//
ID   1.5.3.n1
DE   Transferred entry: 1.5.3.16.
//
ID   1.5.3.n2
DE   Transferred entry: 1.5.3.16.
//
ID   1.5.3.n3
DE   Transferred entry: 1.5.3.13 and 1.5.3.16.
//
ID   1.5.3.n4
DE   Transferred entry: 1.5.3.13.
//
ID   1.5.3.n5
DE   Transferred entry: 1.5.3.16.
//
ID   1.5.3.n6
DE   Transferred entry: 1.5.3.14 and 1.5.3.15.
//
ID   1.5.3.n7
DE   Transferred entry: 1.5.3.14 and 1.5.3.15.
//
ID   1.5.3.n8
DE   Transferred entry: 1.5.3.14 and 1.5.3.15.
//
ID   1.5.3.n9
DE   Transferred entry: 1.5.3.14 and 1.5.3.15.
//
ID   1.5.3.n10
DE   Transferred entry: 1.5.3.13.
//
ID   1.5.4.1
DE   Pyrimidodiazepine synthase.
CA   A pyrimidodiazepine + glutathione disulfide + H(2)O = 6-pyruvoyl-
CA   tetrahydropterin + 2 glutathione.
CC   -!- In the reverse direction of reaction, the reduction of 6-pyruvoyl-
CC       tetrahydropterin is accompanied by the opening of the 6-membered
CC       pyrazine ring and the formation of the 7-membered diazepine ring.
CC   -!- The pyrimidodiazepine involved is an acetyldihydro derivative.
CC   -!- Involved in the formation of the eye pigment drosopterin in
CC       Drosophila melanogaster.
//
ID   1.5.5.1
DE   Electron-transferring-flavoprotein dehydrogenase.
AN   Electron transfer flavoprotein-ubiquinone oxidoreductase.
AN   ETF dehydrogenase.
AN   ETF-QO.
AN   ETF-ubiquinone oxidoreductase.
CA   Reduced electron-transferring flavoprotein + ubiquinone = electron-
CA   transferring flavoprotein + ubiquinol.
CF   FAD; Iron-sulfur.
CC   -!- Forms part of the mitochondrial electron-transfer system.
DR   P94132, ETFD_ACIAD ;  Q2KIG0, ETFD_BOVIN ;  Q11190, ETFD_CAEEL ;
DR   Q54XM6, ETFD_DICDI ;  Q16134, ETFD_HUMAN ;  Q921G7, ETFD_MOUSE ;
DR   P55932, ETFD_PARDE ;  P55931, ETFD_PIG   ;  Q5RDD3, ETFD_PONAB ;
DR   Q9HZP5, ETFD_PSEAE ;  Q6UPE1, ETFD_RAT   ;  P87111, ETFD_SCHPO ;
DR   Q08822, ETFD_YEAST ;
//
ID   1.5.7.1
DE   Methylenetetrahydrofolate reductase (ferredoxin).
AN   5,10-methylenetetrahydrofolate reductase.
CA   5-methyltetrahydrofolate + 2 oxidized ferredoxin = 5,10-
CA   methylenetetrahydrofolate + 2 reduced ferredoxin + 2 H(+).
CF   Flavoprotein; Iron-sulfur; Zinc.
CC   -!- The enzyme from Clostridium formicoaceticum catalyzes the reduction
CC       of methylene blue, menadione, benzyl viologen, rubredoxin or FAD with
CC       5-methyltetrahydrofolate and the oxidation of reduced ferredoxin or
CC       FADH(2) with 5,10-methylenetetrahydrofolate.
CC   -!- However, unlike EC 1.5.1.20, there is no activity with NAD(P)H.
//
ID   1.5.8.1
DE   Dimethylamine dehydrogenase.
AN   DMADh.
CA   Dimethylamine + H(2)O + electron-transferring flavoprotein = methylamine
CA   + formaldehyde + reduced electron-transferring flavoprotein.
CF   FAD; Iron-sulfur.
CC   -!- Formerly EC 1.5.99.10.
DR   Q48303, DHDM_HYPSX ;
//
ID   1.5.8.2
DE   Trimethylamine dehydrogenase.
AN   TMADh.
CA   Trimethylamine + H(2)O + electron-transferring flavoprotein =
CA   dimethylamine + formaldehyde + reduced electron-transferring
CA   flavoprotein.
CF   FMN; Iron-sulfur.
CC   -!- A number of alkyl-substituted derivatives of trimethylamine can also
CC       act as electron donors.
CC   -!- Phenazine methosulfate and 2,6-dichloroindophenol can act as electron
CC       acceptors.
CC   -!- Formerly EC 1.5.99.7.
DR   P16099, DHTM_METME ;
//
ID   1.5.99.1
DE   Sarcosine dehydrogenase.
CA   Sarcosine + acceptor + H(2)O = glycine + formaldehyde + reduced acceptor.
CF   FMN.
DR   Q9UL12, SARDH_HUMAN;  Q99LB7, SARDH_MOUSE;  Q64380, SARDH_RAT  ;
//
ID   1.5.99.2
DE   Dimethylglycine dehydrogenase.
CA   N,N-dimethylglycine + acceptor + H(2)O = sarcosine + formaldehyde +
CA   reduced acceptor.
CF   FAD.
DR   Q9UI17, M2GD_HUMAN ;  Q9DBT9, M2GD_MOUSE ;  Q63342, M2GD_RAT   ;
//
ID   1.5.99.3
DE   L-pipecolate dehydrogenase.
CA   L-pipecolate + acceptor = (S)-2,3,4,5-tetrahydropyridine-2-carboxylate +
CA   reduced acceptor.
CC   -!- The product reacts with water to form (S)-2-amino-6-oxohexanoate.
//
ID   1.5.99.4
DE   Nicotine dehydrogenase.
CA   Nicotine + acceptor + H(2)O = (S)-6-hydroxynicotine + reduced acceptor.
CF   FMN.
CC   -!- Acts on both (R)- and (S)-isomers.
//
ID   1.5.99.5
DE   Methylglutamate dehydrogenase.
CA   N-methyl-L-glutamate + acceptor + H(2)O = L-glutamate + formaldehyde +
CA   reduced acceptor.
CC   -!- A number of N-methyl-substituted amino acids can act as donors.
CC   -!- 2,6-dichloroindophenol is the best acceptor.
//
ID   1.5.99.6
DE   Spermidine dehydrogenase.
CA   Spermidine + acceptor + H(2)O = 1,3-diaminopropane + 4-aminobutanal +
CA   reduced acceptor.
CF   FAD; Heme.
CC   -!- Ferricyanide, 2,6-dichloroindophenol and cytochrome c can act as
CC       acceptor.
CC   -!- 4-aminobutanal condenses non-enzymically to 1-pyrroline.
//
ID   1.5.99.7
DE   Transferred entry: 1.5.8.2.
//
ID   1.5.99.8
DE   Proline dehydrogenase.
CA   L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor.
CF   FAD.
CC   -!- In many organisms, ranging from bacteria to mammals, proline is
CC       oxidized to glutamate in a two-step process involving this enzyme and
CC       EC 1.5.1.12.
CC   -!- Both activities are carried out by the same enzyme in enterobacteria.
PR   PROSITE; PDOC00068;
DR   P92983, PROD1_ARATH;  Q8RMG1, PROD1_BACNA;  O32179, PROD1_BACSU;
DR   Q6NKX1, PROD2_ARATH;  Q8L2I5, PROD2_BACNA;  P94390, PROD2_BACSU;
DR   A6QQ74, PROD2_BOVIN;  Q9UF12, PROD2_HUMAN;  Q8VCZ9, PROD2_MOUSE;
DR   Q2V057, PROD2_RAT  ;  Q6PAY6, PROD2_XENLA;  Q148G5, PROD_BOVIN ;
DR   O45228, PROD_CAEEL ;  Q86H28, PROD_DICDI ;  Q04499, PROD_DROME ;
DR   O43272, PROD_HUMAN ;  Q9WU79, PROD_MOUSE ;  O74524, PROD_SCHPO ;
DR   P09368, PUT1_YEAST ;  P09546, PUTA_ECOLI ;  O52485, PUTA_ENTAE ;
DR   P23725, PUTA_KLEPN ;  P95629, PUTA_RHIME ;  P10503, PUTA_SALTY ;
//
ID   1.5.99.9
DE   Methylenetetrahydromethanopterin dehydrogenase.
AN   5,10-methylenetetrahydromethanopterin dehydrogenase.
AN   N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase.
CA   5,10-methylenetetrahydromethanopterin + coenzyme F420 = 5,10-
CA   methenyltetrahydromethanopterin + reduced coenzyme F420.
CC   -!- Coenzyme F420 is a 7,8-didemethyl-8-hydroxy-5-deazariboflavin
CC       derivative; methanopterin is a pterin analog.
CC   -!- The enzyme is involved in the formation of methane from CO(2) in
CC       Methanobacterium thermoautotrophicum.
DR   O29544, MTD_ARCFU  ;  A6UWS1, MTD_META3  ;  Q8THT2, MTD_METAC  ;
DR   A7I5N7, MTD_METB6  ;  Q2FU89, MTD_METHJ  ;  Q58441, MTD_METJA  ;
DR   P94951, MTD_METKA  ;  A2SPK1, MTD_METLZ  ;  A4FZG7, MTD_METM5  ;
DR   A6VJ05, MTD_METM7  ;  Q8PXV8, MTD_METMA  ;  A3CSZ5, MTD_METMJ  ;
DR   Q6M099, MTD_METMP  ;  B8GJQ7, MTD_METPE  ;  A5UMI1, MTD_METS3  ;
DR   Q2NHQ2, MTD_METST  ;  Q50501, MTD_METTH  ;  P55300, MTD_METTM  ;
DR   A6URY5, MTD_METVS  ;
//
ID   1.5.99.10
DE   Transferred entry: 1.5.8.1.
//
ID   1.5.99.11
DE   5,10-methylenetetrahydromethanopterin reductase.
AN   5,10-methylenetetrahydromethanopterin cyclohydrolase.
AN   Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin
AN   reductase.
AN   Methylene-H(4)MPT reductase.
AN   N(5),N(10)-methylenetetrahydromethanopterin reductase.
AN   N(5),N(10)-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase.
CA   5-methyltetrahydromethanopterin + coenzyme F420 = 5,10-
CA   methylenetetrahydromethanopterin + reduced coenzyme F420.
CC   -!- Catalyzes an intermediate step in methanogenesis from CO(2) and H(2)
CC       in archaea.
DR   O29196, MER_ARCFU  ;  Q8TJP7, MER_METAC  ;  Q46FV4, MER_METBF  ;
DR   Q58929, MER_METJA  ;  Q8TXY4, MER_METKA  ;  Q8PZ66, MER_METMA  ;
DR   O27784, MER_METTH  ;  Q9UXP0, MER_METTI  ;  Q50744, MER_METTM  ;
//
ID   1.5.99.12
DE   Cytokinin dehydrogenase.
AN   Cytokinin oxidase.
CA   N(6)-dimethylallyladenine + acceptor + H(2)O = adenine + 3-methylbut-2-
CA   enal + reduced acceptor.
CF   FAD.
CC   -!- Converts zeatin and related cytokinins.
CC   -!- Catalyzes the oxidation of cytokinins, a family of N(6)-substituted
CC       adenine derivatives that are plant hormones, where the substituent is
CC       a dimethylallyl or other prenyl group.
CC   -!- Although this activity was previously thought to be catalyzed by a
CC       hydrogen-peroxide-forming oxidase, this enzyme does not require
CC       oxygen for activity and does not form hydrogen peroxide.
CC   -!- 2,6-dichloroindophenol, methylene blue, nitroblue tetrazolium,
CC       phenazine methosulfate and Cu(2+) in the presence of imidazole can
CC       act as acceptors.
DR   Q5Z620, CKX10_ORYSJ;  Q6Z955, CKX11_ORYSJ;  O22213, CKX1_ARATH ;
DR   Q9T0N8, CKX1_MAIZE ;  Q0JQ12, CKX1_ORYSJ ;  Q9FUJ3, CKX2_ARATH ;
DR   Q4ADV8, CKX2_ORYSJ ;  Q9LTS3, CKX3_ARATH ;  Q8LNV6, CKX3_ORYSJ ;
DR   Q9FUJ2, CKX4_ARATH ;  Q5JLP4, CKX4_ORYSJ ;  Q67YU0, CKX5_ARATH ;
DR   Q5ZAY9, CKX5_ORYSJ ;  Q9LY71, CKX6_ARATH ;  Q6YW51, CKX6_ORYSJ ;
DR   Q9FUJ1, CKX7_ARATH ;  Q6YW50, CKX7_ORYSJ ;  A2XVN3, CKX8_ORYSI ;
DR   A3AVP1, CKX8_ORYSJ ;  Q75K78, CKX9_ORYSJ ;  P58763, CKX_WHEAT  ;
//
ID   1.5.99.13
DE   D-proline dehydrogenase.
AN   D-pro dehydrogenase.
AN   D-pro DH.
CA   D-proline + acceptor + H(2)O = 1-pyrroline-2-carboxylate + reduced
CA   acceptor.
CF   FAD.
CC   -!- The enzyme prefers D-proline and acts on other D-amino acid with
CC       lower efficiency.
//
ID   1.6.1.1
DE   NAD(P)(+) transhydrogenase (B-specific).
AN   Nicotinamide nucleotide transhydrogenase.
AN   Pyridine nucleotide transhydrogenase.
CA   NADPH + NAD(+) = NADP(+) + NADH.
CF   FAD.
CC   -!- B-specific with respect to both NAD(+) and NADP(+).
CC   -!- Also acts with deamino coenzymes.
PR   PROSITE; PDOC00073;
DR   C1DR10, STHA_AZOVD ;  Q9XBQ9, STHA_AZOVI ;  Q1QX78, STHA_CHRSD ;
DR   A8AKW0, STHA_CITK8 ;  Q48A14, STHA_COLP3 ;  A7ZUI2, STHA_ECO24 ;
DR   B7UNU0, STHA_ECO27 ;  B7MIA0, STHA_ECO45 ;  B7LA64, STHA_ECO55 ;
DR   Q8X727, STHA_ECO57 ;  B5Z064, STHA_ECO5E ;  B7NU38, STHA_ECO7I ;
DR   B7MR55, STHA_ECO81 ;  B7M718, STHA_ECO8A ;  C5A0R1, STHA_ECOBW ;
DR   B1XBX3, STHA_ECODH ;  A8A770, STHA_ECOHS ;  A1AIE2, STHA_ECOK1 ;
DR   Q0TA96, STHA_ECOL5 ;  Q8FB93, STHA_ECOL6 ;  B1IVB6, STHA_ECOLC ;
DR   P27306, STHA_ECOLI ;  B7NFR2, STHA_ECOLU ;  B6I5I0, STHA_ECOSE ;
DR   B1LNS2, STHA_ECOSM ;  Q1R3U7, STHA_ECOUT ;  A4WG49, STHA_ENT38 ;
DR   Q6CZB1, STHA_ERWCT ;  B2VGA0, STHA_ERWT9 ;  B7LUN3, STHA_ESCF3 ;
DR   Q2SIP2, STHA_HAHCH ;  C4K3I8, STHA_HAMD5 ;  B5XZ14, STHA_KLEP3 ;
DR   A6TGE6, STHA_KLEP7 ;  A1U1Y5, STHA_MARAV ;  A6VW16, STHA_MARMS ;
DR   P66007, STHA_MYCBO ;  A1KM51, STHA_MYCBP ;  C1AFH2, STHA_MYCBT ;
DR   A5U665, STHA_MYCTA ;  P66006, STHA_MYCTU ;  P71317, STHA_PECCC ;
DR   Q7MBG9, STHA_PHOLL ;  Q6LLT9, STHA_PHOPR ;  B4F1H1, STHA_PROMH ;
DR   Q48KI8, STHA_PSE14 ;  A6V3A6, STHA_PSEA7 ;  B7UZU5, STHA_PSEA8 ;
DR   Q02PF5, STHA_PSEAB ;  P57112, STHA_PSEAE ;  Q1I7F0, STHA_PSEE4 ;
DR   Q4KFA6, STHA_PSEF5 ;  O05139, STHA_PSEFL ;  C3K4W1, STHA_PSEFS ;
DR   A4XSQ1, STHA_PSEMY ;  A5W6F5, STHA_PSEP1 ;  Q3K9F5, STHA_PSEPF ;
DR   B0KH90, STHA_PSEPG ;  Q88KY8, STHA_PSEPK ;  B1J606, STHA_PSEPW ;
DR   Q884I6, STHA_PSESM ;  Q4ZV77, STHA_PSEU2 ;  A4VMU6, STHA_PSEU5 ;
DR   Q57H91, STHA_SALCH ;  B5QXQ7, STHA_SALEP ;  B5REZ6, STHA_SALG2 ;
DR   Q5PK71, STHA_SALPA ;  A9N0H2, STHA_SALPB ;  C0Q478, STHA_SALPC ;
DR   B5BJN6, STHA_SALPK ;  P66009, STHA_SALTI ;  P66008, STHA_SALTY ;
DR   A8GL77, STHA_SERP5 ;  B2TWF7, STHA_SHIB3 ;  Q83MI1, STHA_SHIFL ;
DR   Q2NQZ3, STHA_SODGM ;  A5F4K5, STHA_VIBC3 ;  P50529, STHA_VIBCH ;
DR   C3LPZ2, STHA_VIBCM ;  Q5E212, STHA_VIBF1 ;  Q87KN5, STHA_VIBPA ;
DR   B7VM91, STHA_VIBSL ;  Q8DD46, STHA_VIBVU ;  Q7MQ83, STHA_VIBVY ;
DR   A1JI37, STHA_YERE8 ;  A7FD10, STHA_YERP3 ;  Q1CBU5, STHA_YERPA ;
DR   B2JZF3, STHA_YERPB ;  Q8ZA97, STHA_YERPE ;  A9R6N5, STHA_YERPG ;
DR   Q1CNP4, STHA_YERPN ;  A4TRG4, STHA_YERPP ;  Q66G61, STHA_YERPS ;
DR   B1JQ50, STHA_YERPY ;
//
ID   1.6.1.2
DE   NAD(P)(+) transhydrogenase (AB-specific).
AN   Pyridine nucleotide transhydrogenase.
AN   Transhydrogenase.
CA   NADPH + NAD(+) = NADP(+) + NADH.
CC   -!- The enzyme from heart mitochondria is A-specific with respect to
CC       NAD(+) and B-specific with respect to NADP(+) (cf. EC 1.6.1.1.).
PR   PROSITE; PDOC00654;
DR   P11024, NNTM_BOVIN ;  Q13423, NNTM_HUMAN ;  Q61941, NNTM_MOUSE ;
DR   Q2RSB2, PNTAA_RHORT;  P0C186, PNTAA_RHORU;  P41077, PNTAA_RICPR;
DR   Q2RSB3, PNTAB_RHORT;  P0C187, PNTAB_RHORU;  P51995, PNTAB_RICPR;
DR   P07001, PNTA_ECOLI ;  P43842, PNTA_HAEIN ;  P0AB69, PNTB_ECO57 ;
DR   P0AB68, PNTB_ECOL6 ;  P0AB67, PNTB_ECOLI ;  P43010, PNTB_HAEIN ;
DR   Q2RSB4, PNTB_RHORT ;  P0C188, PNTB_RHORU ;  P0AB70, PNTB_SHIFL ;
//
ID   1.6.2.1
DE   Transferred entry: 1.6.99.3.
//
ID   1.6.2.2
DE   Cytochrome-b5 reductase.
CA   NADH + 2 ferricytochrome b5 = NAD(+) + H(+) + 2 ferrocytochrome b5.
CF   FAD.
DR   A7THS1, MCR1A_VANPO;  A7TM72, MCR1B_VANPO;  A6R1T7, MCR1_AJECN ;
DR   Q75C62, MCR1_ASHGO ;  A1CRK9, MCR1_ASPCL ;  Q4WJW8, MCR1_ASPFU ;
DR   A2Q898, MCR1_ASPNC ;  Q2UKB8, MCR1_ASPOR ;  Q0CRD8, MCR1_ASPTN ;
DR   A6SI59, MCR1_BOTFB ;  Q59M70, MCR1_CANAL ;  Q6FUX5, MCR1_CANGA ;
DR   Q2HG02, MCR1_CHAGB ;  Q1DXN1, MCR1_COCIM ;  Q6BQ54, MCR1_DEBHA ;
DR   Q5BG98, MCR1_EMENI ;  Q6CS27, MCR1_KLULA ;  A5E5C5, MCR1_LODEL ;
DR   A4QR21, MCR1_MAGO7 ;  A1D4H0, MCR1_NEOFI ;  Q7SFY2, MCR1_NEUCR ;
DR   Q0U9W5, MCR1_PHANO ;  A5DQE4, MCR1_PICGU ;  A3LT66, MCR1_PICST ;
DR   A7EKT5, MCR1_SCLS1 ;  Q4P7Y8, MCR1_USTMA ;  Q6C9G8, MCR1_YARLI ;
DR   A6ZZH2, MCR1_YEAS7 ;  P36060, MCR1_YEAST ;  Q3MHW9, NB5R1_BOVIN;
DR   Q9UHQ9, NB5R1_HUMAN;  Q9DB73, NB5R1_MOUSE;  Q5EB81, NB5R1_RAT  ;
DR   Q5ZHX7, NB5R2_CHICK;  Q0P487, NB5R2_DANRE;  Q6BCY4, NB5R2_HUMAN;
DR   Q3KNK3, NB5R2_MOUSE;  Q6AY12, NB5R2_RAT  ;  Q5PQA4, NB5R2_XENLA;
DR   Q5BJ68, NB5R2_XENTR;  P07514, NB5R3_BOVIN;  Q0X0E5, NB5R3_CANFA;
DR   P00387, NB5R3_HUMAN;  Q60HG4, NB5R3_MACFA;  Q9DCN2, NB5R3_MOUSE;
DR   P83686, NB5R3_PIG  ;  P20070, NB5R3_RAT  ;  Q32LH7, NB5R4_BOVIN;
DR   Q502I6, NB5R4_DANRE;  Q7L1T6, NB5R4_HUMAN;  Q3TDX8, NB5R4_MOUSE;
DR   Q68EJ0, NB5R4_RAT  ;  Q28CZ9, NB5R4_XENTR;  Q6IPT4, NB5R5_HUMAN;
DR   B1AS42, NB5R5_MOUSE;  A6R2K7, NCB5R_AJECN;  P83291, NCB5R_ARATH;
DR   Q75AL4, NCB5R_ASHGO;  A1C7E9, NCB5R_ASPCL;  Q4X0B5, NCB5R_ASPFU;
DR   A2QCV4, NCB5R_ASPNC;  Q2UFN3, NCB5R_ASPOR;  Q0CY37, NCB5R_ASPTN;
DR   Q59P03, NCB5R_CANAL;  Q6FLT3, NCB5R_CANGA;  Q1DWN4, NCB5R_COCIM;
DR   P0CP15, NCB5R_CRYNB;  P0CP14, NCB5R_CRYNJ;  Q6BUX2, NCB5R_DEBHA;
DR   Q54NC1, NCB5R_DICDI;  Q5AZB4, NCB5R_EMENI;  Q6CID0, NCB5R_KLULA;
DR   B0CQN7, NCB5R_LACBS;  A5E7U2, NCB5R_LODEL;  A4R935, NCB5R_MAGO7;
DR   Q9UR35, NCB5R_MORAP;  A1DHW1, NCB5R_NEOFI;  Q7RXL1, NCB5R_NEUCR;
DR   Q0UEY4, NCB5R_PHANO;  A5DQ25, NCB5R_PICGU;  A3GF86, NCB5R_PICST;
DR   O74557, NCB5R_SCHPO;  Q4PGW7, NCB5R_USTMA;  A7TNL7, NCB5R_VANPO;
DR   Q6CA86, NCB5R_YARLI;  A6ZVM6, NCB5R_YEAS7;  P38626, NCB5R_YEAST;
//
ID   1.6.2.3
DE   Deleted entry.
//
ID   1.6.2.4
DE   NADPH--hemoprotein reductase.
AN   Aldehyde reductase (NADPH-dependent).
AN   CPR.
AN   Cytochrome c reductase (reduced nicotinamide adenine dinucleotide
AN   phosphate, NADPH, NADPH-dependent).
AN   Cytochrome P450 reductase.
AN   Dihydroxynicotinamide adenine dinucleotide phosphate-cytochrome c
AN   reductase.
AN   FAD-cytochrome c reductase.
AN   Ferrihemoprotein P-450 reductase.
AN   NADP--cytochrome c reductase.
AN   NADP--cytochrome reductase.
AN   NADPH--cytochrome c oxidoreductase.
AN   NADPH--cytochrome c reductase.
AN   NADPH--cytochrome P450 oxidoreductase.
AN   NADPH--cytochrome P450 reductase.
AN   NADPH--ferricytochrome c oxidoreductase.
AN   NADPH--ferrihemoprotein reductase.
AN   NADPH-dependent cytochrome c reductase.
AN   NADPH:ferrihemoprotein oxidoreductase.
AN   NADPH:P450 reductase.
AN   Reduced nicotinamide adenine dinucleotide phosphate-cytochrome c
AN   reductase.
AN   Reductase, cytochrome c (reduced nicotinamide adenine dinucleotide
AN   phosphate).
AN   TPNH(2) cytochrome c reductase.
AN   TPNH-cytochrome c reductase.
CA   NADPH + n oxidized hemoprotein = NADP(+) + n reduced hemoprotein.
CF   FAD; FMN.
CC   -!- The number n in the equation is 1 if the hemoprotein undergoes a
CC       2-electron reduction, and is 2 if it undergoes a 1-electron
CC       reduction.
CC   -!- The enzyme catalyzes the reduction of the heme-thiolate-dependent
CC       monooxygenases, such as EC 1.14.14.1, and reduction of EC 1.14.99.3.
CC   -!- It is part of the microsomal hydroxylating system.
CC   -!- It also reduces cytochrome b5 and cytochrome c.
DR   Q9Y8G7, C505_FUSOX ;  P14779, CPXB_BACME ;  O08394, CYPD_BACSU ;
DR   O08336, CYPE_BACSU ;  Q4WM67, NCPR_ASPFU ;  A2QS05, NCPR_ASPNC ;
DR   Q00141, NCPR_ASPNG ;  Q2UHA7, NCPR_ASPOR ;  Q0CMM0, NCPR_ASPTN ;
DR   Q3SYT8, NCPR_BOVIN ;  P50126, NCPR_CANMA ;  P37201, NCPR_CANTR ;
DR   Q05001, NCPR_CATRO ;  P37039, NCPR_CAVPO ;  Q27597, NCPR_DROME ;
DR   Q5BFT5, NCPR_EMENI ;  P16435, NCPR_HUMAN ;  P37040, NCPR_MOUSE ;
DR   Q07994, NCPR_MUSDO ;  Q9HDG2, NCPR_PHACH ;  P04175, NCPR_PIG   ;
DR   P00389, NCPR_RABIT ;  P00388, NCPR_RAT   ;  P19618, NCPR_SALTR ;
DR   P36587, NCPR_SCHPO ;  P37116, NCPR_VIGRR ;  P16603, NCPR_YEAST ;
//
ID   1.6.2.5
DE   NADPH--cytochrome-c2 reductase.
CA   NADPH + 2 ferricytochrome c2 = NADP(+) + H(+) + 2 ferrocytochrome c2.
CF   FAD.
//
ID   1.6.2.6
DE   Leghemoglobin reductase.
CA   NAD(P)H + 2 ferrileghemoglobin = NAD(P)(+) + 2 ferroleghemoglobin.
//
ID   1.6.3.1
DE   NAD(P)H oxidase.
AN   Dual oxidase.
AN   ThOX.
AN   THOX2.
AN   Thyroid NADPH oxidase.
AN   Thyroid oxidase.
AN   Thyroid oxidase 2.
CA   NAD(P)H + O(2) = NAD(P)(+) + H(2)O(2).
CF   Calcium; FAD; Heme.
CC   -!- When calcium is present, this transmembrane glycoprotein generates
CC       H(2)O(2) by transfering electrons from intracellular NAD(P)H to
CC       extracellular molecular oxygen.
CC   -!- The electron bridge within the enzyme contains one molecule of FAD
CC       and probably two heme groups.
CC   -!- This flavoprotein is expressed at the apical membrane of thyrocytes,
CC       and provides H(2)O(2) for the thyroid peroxidase-catalyzed
CC       biosynthesis of thyroid hormones.
PR   PROSITE; PDOC00394;
DR   O61213, DUOX1_CAEEL;  Q9MZF4, DUOX1_CANFA;  Q9NRD9, DUOX1_HUMAN;
DR   Q8HZK3, DUOX1_PIG  ;  Q8CIY2, DUOX1_RAT  ;  Q9NRD8, DUOX2_HUMAN;
DR   Q8HZK2, DUOX2_PIG  ;  Q9ES45, DUOX2_RAT  ;  Q9VQH2, DUOX_DROME ;
//
ID   1.6.4.1
DE   Transferred entry: 1.8.1.6.
//
ID   1.6.4.2
DE   Transferred entry: 1.8.1.7.
//
ID   1.6.4.3
DE   Transferred entry: 1.8.1.4.
//
ID   1.6.4.4
DE   Transferred entry: 1.8.1.8.
//
ID   1.6.4.5
DE   Transferred entry: 1.8.1.9.
//
ID   1.6.4.6
DE   Transferred entry: 1.8.1.10.
//
ID   1.6.4.7
DE   Transferred entry: 1.8.1.11.
//
ID   1.6.4.8
DE   Transferred entry: 1.8.1.12.
//
ID   1.6.4.9
DE   Transferred entry: 1.8.1.13.
//
ID   1.6.4.10
DE   Transferred entry: 1.8.1.14.
//
ID   1.6.5.1
DE   Deleted entry.
//
ID   1.6.5.2
DE   NAD(P)H dehydrogenase (quinone).
AN   Azoreductase.
AN   Dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate,
AN   quinone).
AN   Diaphorase.
AN   DT-diaphorase.
AN   Flavoprotein NAD(P)H-quinone reductase.
AN   Menadione oxidoreductase.
AN   Menadione reductase.
AN   NAD(P)H dehydrogenase.
AN   NAD(P)H menadione reductase.
AN   NAD(P)H(2) dehydrogenase (quinone).
AN   NAD(P)H-quinone dehydrogenase.
AN   NAD(P)H-quinone oxidoreductase.
AN   NAD(P)H: menadione oxidoreductase.
AN   NAD(P)H:(quinone-acceptor)oxidoreductase.
AN   NADH-menadione reductase.
AN   Naphthoquinone reductase.
AN   p-benzoquinone reductase.
AN   Phylloquinone reductase.
AN   Quinone reductase.
AN   Reduced NAD(P)H dehydrogenase.
AN   Reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase.
AN   Viologen accepting pyridine nucleotide oxidoreductase.
AN   Vitamin K reductase.
AN   Vitamin-K reductase.
CA   NAD(P)H + a quinone = NAD(P)(+) + a hydroquinone.
CF   FAD.
CC   -!- The enzyme catalyzes a two-electron reduction and has a preference
CC       for short-chain acceptor quinones, such as ubiquinone, benzoquinone,
CC       juglone and duroquinone.
CC   -!- The animal, but not the plant, form of the enzyme is inhibited by
CC       dicoumarol.
CC   -!- Formerly EC 1.6.99.2.
DR   O53355, LPDA_MYCTU ;  Q8CHK7, NQO1_CAVPO ;  P15559, NQO1_HUMAN ;
DR   Q64669, NQO1_MOUSE ;  Q5RD31, NQO1_PONAB ;  P05982, NQO1_RAT   ;
DR   Q941Z0, NQR1_ORYSJ ;  Q941Y8, NQR2_ORYSJ ;  Q9LK88, NQR_ARATH  ;
DR   Q8H9D2, NQR_SOLTU  ;  P39315, QOR2_ECOLI ;
//
ID   1.6.5.3
DE   NADH:ubiquinone reductase (H(+)-translocating).
AN   Coenzyme Q reductase.
AN   Complex I (electron transport chain).
AN   Complex I (mitochondrial electron transport).
AN   Dihydronicotinamide adenine dinucleotide-coenzyme Q reductase.
AN   DPNH-coenzyme Q reductase.
AN   DPNH-ubiquinone reductase.
AN   Electron transfer complex I.
AN   Mitochondrial electron transport complex 1.
AN   Mitochondrial electron transport complex I.
AN   NADH coenzyme Q1 reductase.
AN   NADH dehydrogenase (ubiquinone).
AN   NADH-coenzyme Q reductase.
AN   NADH-CoQ oxidoreductase.
AN   NADH-CoQ reductase.
AN   NADH-ubiquinone oxidoreductase.
AN   NADH-ubiquinone reductase.
AN   Reduced nicotinamide adenine dinucleotide-coenzyme Q reductase.
AN   Ubiquinone reductase.
CA   NADH + ubiquinone = NAD(+) + ubiquinol.
CF   FMN; Iron-sulfur.
CC   -!- The complex is present in mitochondria and aerobic bacteria.
CC   -!- Breakdown of the complex can release EC 1.6.99.3.
CC   -!- In photosynthetic bacteria, reversed electron transport through this
CC       enzyme can reduce NAD(+) to NADH.
PR   PROSITE; PDOC00468;
PR   PROSITE; PDOC00521;
PR   PROSITE; PDOC00554;
PR   PROSITE; PDOC00555;
PR   PROSITE; PDOC00570;
PR   PROSITE; PDOC00843;
PR   PROSITE; PDOC00858;
DR   O14121, NDH1_SCHPO ;  P40215, NDH1_YEAST ;  O43090, NDH2_SCHPO ;
DR   Q07500, NDH2_YEAST ;  Q42599, NDS8A_ARATH;  Q9FX83, NDS8B_ARATH;
DR   Q37373, NDUS1_ACACA;  Q9FGI6, NDUS1_ARATH;  P15690, NDUS1_BOVIN;
DR   Q2LCP5, NDUS1_DICCI;  Q34312, NDUS1_DICDI;  Q94511, NDUS1_DROME;
DR   Q0MQG1, NDUS1_GORGO;  P28331, NDUS1_HUMAN;  Q4R6K9, NDUS1_MACFA;
DR   P86203, NDUS1_MESAU;  Q91VD9, NDUS1_MOUSE;  P24918, NDUS1_NEUCR;
DR   Q0MQG2, NDUS1_PANTR;  P0CB67, NDUS1_PONAB;  P0CB68, NDUS1_PONPY;
DR   Q66HF1, NDUS1_RAT  ;  O21241, NDUS1_RECAM;  Q43644, NDUS1_SOLTU;
DR   Q37384, NDUS2_ACACA;  P93306, NDUS2_ARATH;  P17694, NDUS2_BOVIN;
DR   Q93873, NDUS2_CAEEL;  Q9TAJ7, NDUS2_CAFRO;  Q2LCR5, NDUS2_DICCI;
DR   Q23883, NDUS2_DICDI;  Q0MQG4, NDUS2_GORGO;  O75306, NDUS2_HUMAN;
DR   P86250, NDUS2_MESAU;  Q91WD5, NDUS2_MOUSE;  Q9TC96, NDUS2_NEPOL;
DR   P22142, NDUS2_NEUCR;  Q36450, NDUS2_NICSY;  Q5DUX5, NDUS2_NYCOV;
DR   Q0MQG5, NDUS2_PANTR;  P15689, NDUS2_PARTE;  Q0MQG3, NDUS2_PONPY;
DR   Q37619, NDUS2_PROWI;  Q37720, NDUS2_PYLLI;  Q641Y2, NDUS2_RAT  ;
DR   O21270, NDUS2_RECAM;  P80264, NDUS2_SOLTU;  P21301, NDUS2_TRYBB;
DR   Q37383, NDUS3_ACACA;  Q95748, NDUS3_ARATH;  Q33994, NDUS3_BETTR;
DR   Q37787, NDUS3_BETVU;  P23709, NDUS3_BOVIN;  Q00673, NDUS3_CANMA;
DR   Q2LCR4, NDUS3_DICCI;  P22237, NDUS3_DICDI;  Q0MQG7, NDUS3_GORGO;
DR   O75489, NDUS3_HUMAN;  P34944, NDUS3_MARPO;  P86217, NDUS3_MESAU;
DR   Q9DCT2, NDUS3_MOUSE;  P23710, NDUS3_NEUCR;  Q35322, NDUS3_ORYSJ;
DR   Q0MQG8, NDUS3_PANTR;  P15601, NDUS3_PARPR;  P15600, NDUS3_PARTE;
DR   Q34011, NDUS3_PATWE;  Q0MQG6, NDUS3_PONPY;  Q37622, NDUS3_PROWI;
DR   O21271, NDUS3_RECAM;  P80261, NDUS3_SOLTU;  Q42577, NDUS7_ARATH;
DR   P42026, NDUS7_BOVIN;  P42027, NDUS7_BRAOL;  A8XFG2, NDUS7_CAEBR;
DR   Q94360, NDUS7_CAEEL;  Q0MQH9, NDUS7_GORGO;  O75251, NDUS7_HUMAN;
DR   Q9DC70, NDUS7_MOUSE;  O47950, NDUS7_NEUCR;  Q0MQI0, NDUS7_PANTR;
DR   P15602, NDUS7_PARTE;  P0CB83, NDUS7_PONAB;  P0CB84, NDUS7_PONPY;
DR   O21272, NDUS7_RECAM;  Q43844, NDUS7_SOLTU;  Q26783, NDUS7_TRYBB;
DR   P42028, NDUS8_BOVIN;  Q22619, NDUS8_CAEEL;  Q0MQI2, NDUS8_GORGO;
DR   O00217, NDUS8_HUMAN;  Q60HE3, NDUS8_MACFA;  Q8K3J1, NDUS8_MOUSE;
DR   Q12644, NDUS8_NEUCR;  Q0MQI3, NDUS8_PANTR;  P0CB97, NDUS8_PONAB;
DR   P0CB98, NDUS8_PONPY;  O21233, NDUS8_RECAM;  P80269, NDUS8_SOLTU;
DR   O24143, NDUS8_TOBAC;  P30826, NDUS8_TRYBB;  Q9FNN5, NDUV1_ARATH;
DR   Q92406, NDUV1_ASPNG;  P25708, NDUV1_BOVIN;  Q54I90, NDUV1_DICDI;
DR   Q0MQI5, NDUV1_GORGO;  P49821, NDUV1_HUMAN;  Q8HXQ9, NDUV1_MACFA;
DR   Q91YT0, NDUV1_MOUSE;  P24917, NDUV1_NEUCR;  Q0MQI6, NDUV1_PANTR;
DR   Q0MQI4, NDUV1_PONPY;  O94500, NDUV1_SCHPO;  O22769, NDUV2_ARATH;
DR   P04394, NDUV2_BOVIN;  Q20719, NDUV2_CAEEL;  P49820, NDUV2_CANFA;
DR   Q54F10, NDUV2_DICDI;  Q0MQI8, NDUV2_GORGO;  P19404, NDUV2_HUMAN;
DR   Q9D6J6, NDUV2_MOUSE;  P40915, NDUV2_NEUCR;  Q0MQI9, NDUV2_PANTR;
DR   Q0MQI7, NDUV2_PONPY;  P19234, NDUV2_RAT  ;  Q37381, NU1M_ACACA ;
DR   B0FWD8, NU1M_AEDAE ;  P48897, NU1M_ALBCO ;  O47868, NU1M_ALLMI ;
DR   P50658, NU1M_ANAPL ;  P34846, NU1M_ANOGA ;  P33502, NU1M_ANOQU ;
DR   P34847, NU1M_APILI ;  P92558, NU1M_ARATH ;  Q33756, NU1M_ARBLI ;
DR   P19040, NU1M_ARTSA ;  Q37714, NU1M_ARTSF ;  P24875, NU1M_ASCSU ;
DR   P23649, NU1M_ASTFO ;  P23650, NU1M_ASTPE ;  O78693, NU1M_ATEPA ;
DR   P41296, NU1M_BALMU ;  P24967, NU1M_BALPH ;  Q6EMT1, NU1M_BOSIN ;
DR   Q5Y4R0, NU1M_BOSMU ;  P03887, NU1M_BOVIN ;  P69234, NU1M_BRAFL ;
DR   P69235, NU1M_BRALA ;  O78701, NU1M_BRAVA ;  O78700, NU1M_CABUN ;
DR   Q8HEC4, NU1M_CAEBR ;  P24887, NU1M_CAEEL ;  Q9B8D6, NU1M_CANAL ;
DR   P92604, NU1M_CANFA ;  Q3L6Y8, NU1M_CANLU ;  O78679, NU1M_CARAU ;
DR   O78695, NU1M_CEBAP ;  O03850, NU1M_CERSI ;  P18936, NU1M_CHICK ;
DR   P11658, NU1M_CHLRE ;  P48898, NU1M_CHOCR ;  Q70Y30, NU1M_CHODI ;
DR   P08834, NU1M_CITLA ;  Q8M896, NU1M_COEFR ;  Q85UK4, NU1M_COTCH ;
DR   P24968, NU1M_COTJA ;  P48899, NU1M_CYACA ;  Q70Y28, NU1M_CYCDI ;
DR   P24969, NU1M_CYPCA ;  O63623, NU1M_DALCH ;  Q9MIZ0, NU1M_DANRE ;
DR   Q70Y27, NU1M_DASKA ;  O21325, NU1M_DASNO ;  A9RAG3, NU1M_DEBHA ;
DR   Q8M889, NU1M_DIAYO ;  Q2LCR1, NU1M_DICCI ;  Q37313, NU1M_DICDI ;
DR   P41304, NU1M_DIDMA ;  O79546, NU1M_DINSE ;  P51926, NU1M_DROAI ;
DR   P84301, NU1M_DROAL ;  P84303, NU1M_DROAM ;  P84300, NU1M_DROAZ ;
DR   P51930, NU1M_DROBF ;  P51931, NU1M_DROGU ;  P51932, NU1M_DROMD ;
DR   P18929, NU1M_DROME ;  P84305, NU1M_DROMI ;  P84304, NU1M_DROOB ;
DR   P84295, NU1M_DROPB ;  P84294, NU1M_DROPE ;  P51938, NU1M_DROSS ;
DR   P51937, NU1M_DROSU ;  P84302, NU1M_DROTR ;  P07710, NU1M_DROYA ;
DR   Q8W9N6, NU1M_DUGDU ;  Q2I3H4, NU1M_ELEMA ;  Q8M893, NU1M_EMBAL ;
DR   Q8M880, NU1M_EPTNI ;  P92475, NU1M_EQUAS ;  Q70Y26, NU1M_EUPSX ;
DR   P48900, NU1M_FELCA ;  P34186, NU1M_FORLA ;  P55779, NU1M_GADMO ;
DR   Q9T9Z0, NU1M_GORGO ;  P38598, NU1M_HALGR ;  Q9ZZZ1, NU1M_HIPAM ;
DR   Q9MP77, NU1M_HIPDI ;  Q8M897, NU1M_HIPTE ;  P48652, NU1M_HORSE ;
DR   P03886, NU1M_HUMAN ;  Q950U8, NU1M_HYACU ;  Q96126, NU1M_HYLLA ;
DR   O21069, NU1M_LAMFL ;  O03847, NU1M_LATCH ;  P15576, NU1M_LEITA ;
DR   O78696, NU1M_LEMCA ;  P09045, NU1M_LOCMI ;  O47479, NU1M_LOLBL ;
DR   Q8M891, NU1M_LONTH ;  Q9TA29, NU1M_LOXAF ;  Q37546, NU1M_LUMTE ;
DR   O78704, NU1M_MACEU ;  P92659, NU1M_MACRO ;  O78705, NU1M_MACRU ;
DR   Q38PS2, NU1M_MAMPR ;  O78702, NU1M_MANTE ;  P26845, NU1M_MARPO ;
DR   Q37556, NU1M_METSE ;  O78703, NU1M_MONDO ;  P03888, NU1M_MOUSE ;
DR   Q8M873, NU1M_MURFL ;  Q8M867, NU1M_MURSU ;  Q70Y29, NU1M_MYRTR ;
DR   Q00860, NU1M_MYTED ;  O21077, NU1M_MYXGL ;  P08774, NU1M_NEUCR ;
DR   O78709, NU1M_NOTTY ;  O78697, NU1M_NYCCO ;  O80003, NU1M_NYCNO ;
DR   Q8M881, NU1M_NYCVE ;  P31839, NU1M_OENBE ;  P48174, NU1M_ONCMY ;
DR   Q37717, NU1M_ORNAN ;  Q9T9W3, NU1M_PANTR ;  Q9ZXY4, NU1M_PAPHA ;
DR   P12772, NU1M_PARLI ;  P05513, NU1M_PARTE ;  Q96186, NU1M_PECMA ;
DR   O79670, NU1M_PELSU ;  O78710, NU1M_PERGU ;  Q01300, NU1M_PETHY ;
DR   Q37603, NU1M_PETMA ;  O78706, NU1M_PHACI ;  Q00505, NU1M_PHOVI ;
DR   Q8M892, NU1M_PHYEO ;  P48901, NU1M_PICCA ;  O79874, NU1M_PIG   ;
DR   P24995, NU1M_PISOC ;  P19041, NU1M_PODAN ;  Q96182, NU1M_POLOR ;
DR   P92690, NU1M_PONAB ;  Q9T9X9, NU1M_PONPY ;  Q70Y22, NU1M_PRIMA ;
DR   Q8M899, NU1M_PTEGI ;  O79427, NU1M_RABIT ;  P16672, NU1M_RANCA ;
DR   P03889, NU1M_RAT   ;  O99824, NU1M_RHISA ;  Q96189, NU1M_RHIUN ;
DR   Q53AV2, NU1M_SAGLE ;  O78694, NU1M_SAGOE ;  Q37676, NU1M_SALSA ;
DR   O78711, NU1M_SARHA ;  O21408, NU1M_SCYCA ;  O78747, NU1M_SHEEP ;
DR   P50659, NU1M_SIMVI ;  O78715, NU1M_SMICR ;  O78712, NU1M_SMIMA ;
DR   Q9ZZ54, NU1M_SQUAC ;  O21397, NU1M_STRCA ;  P15548, NU1M_STRPU ;
DR   O78714, NU1M_TACAC ;  Q8M888, NU1M_TADIN ;  O78698, NU1M_TAMSI ;
DR   O78699, NU1M_TAMTE ;  Q8M894, NU1M_TAPME ;  Q4JQI7, NU1M_TETNG ;
DR   O48358, NU1M_THYAR ;  Q70Y23, NU1M_TOLMA ;  Q9ZZ38, NU1M_TRIRU ;
DR   O78707, NU1M_TRIVU ;  Q0H8X5, NU1M_USTMA ;  Q94VK0, NU1M_VARBA ;
DR   Q94YT7, NU1M_VARDU ;  Q94VI4, NU1M_VARFL ;  Q94VF8, NU1M_VARJO ;
DR   Q94VC3, NU1M_VARRU ;  O78708, NU1M_VOMUR ;  Q01148, NU1M_WHEAT ;
DR   P03890, NU1M_XENLA ;  Q9B6E8, NU1M_YARLI ;  Q70Y24, NU1M_ZAEPI ;
DR   O78713, NU1M_ZAGBR ;  Q37376, NU2M_ACACA ;  B0FWC6, NU2M_AEDAE ;
DR   Q534E0, NU2M_AILFU ;  Q534B1, NU2M_AILME ;  P48902, NU2M_ALBCO ;
DR   O63767, NU2M_ANAAC ;  O63794, NU2M_ANAAM ;  O63796, NU2M_ANACA ;
DR   O63797, NU2M_ANAFA ;  O63775, NU2M_ANAFO ;  O63798, NU2M_ANAPE ;
DR   Q33636, NU2M_ANOAL ;  P34848, NU2M_ANOGA ;  P33503, NU2M_ANOQU ;
DR   P34849, NU2M_APILI ;  O05000, NU2M_ARATH ;  P19042, NU2M_ARTSA ;
DR   Q37704, NU2M_ARTSF ;  P24877, NU2M_ASCSU ;  Q33819, NU2M_ASTPE ;
DR   P41297, NU2M_BALMU ;  P24970, NU2M_BALPH ;  Q330H3, NU2M_BALPL ;
DR   P15688, NU2M_BETVU ;  Q330B1, NU2M_BONBI ;  Q6EMT0, NU2M_BOSIN ;
DR   Q5Y4Q9, NU2M_BOSMU ;  P03892, NU2M_BOVIN ;  O47434, NU2M_BRAFL ;
DR   O21001, NU2M_BRALA ;  Q8HEC1, NU2M_CAEBR ;  P24889, NU2M_CAEEL ;
DR   Q9B8D2, NU2M_CANAL ;  Q9ZZ65, NU2M_CANFA ;  Q85PR2, NU2M_CANLU ;
DR   Q2TGY6, NU2M_CANRF ;  Q36346, NU2M_CAPHI ;  O78680, NU2M_CARAU ;
DR   Q330F2, NU2M_CARCQ ;  O03197, NU2M_CERSI ;  Q330E6, NU2M_CHEPA ;
DR   P18937, NU2M_CHICK ;  P08740, NU2M_CHLRE ;  P48903, NU2M_CHOCR ;
DR   Q330D8, NU2M_CHRAU ;  Q85PQ8, NU2M_CIVCI ;  P24971, NU2M_COTJA ;
DR   Q2TQ14, NU2M_CROHI ;  Q71MY6, NU2M_CROSG ;  P48904, NU2M_CYACA ;
DR   Q85PQ7, NU2M_CYNPE ;  P24972, NU2M_CYPCA ;  Q9MIY9, NU2M_DANRE ;
DR   O21326, NU2M_DASNO ;  A9RAG4, NU2M_DEBHA ;  Q2LCP8, NU2M_DICCI ;
DR   O21048, NU2M_DICDI ;  P41305, NU2M_DIDMA ;  O79547, NU2M_DINSE ;
DR   Q330A8, NU2M_DOBMI ;  P29867, NU2M_DROMA ;  P03896, NU2M_DROME ;
DR   P29868, NU2M_DROSE ;  P29869, NU2M_DROSI ;  P03895, NU2M_DROYA ;
DR   Q8W9N5, NU2M_DUGDU ;  Q330A7, NU2M_EIDHE ;  Q2I3H3, NU2M_ELEMA ;
DR   P92476, NU2M_EQUAS ;  P48905, NU2M_FELCA ;  P34187, NU2M_FORLA ;
DR   P55780, NU2M_GADMO ;  Q85PP8, NU2M_GENSE ;  Q9T9Y9, NU2M_GORGO ;
DR   P38599, NU2M_HALGR ;  Q9ZZZ0, NU2M_HIPAM ;  P48653, NU2M_HORSE ;
DR   P03891, NU2M_HUMAN ;  Q95704, NU2M_HYLLA ;  Q34799, NU2M_HYLSY ;
DR   O21070, NU2M_LAMFL ;  O03166, NU2M_LATCH ;  Q8LX31, NU2M_LEMCA ;
DR   Q36426, NU2M_LOCMI ;  Q9TA28, NU2M_LOXAF ;  Q34951, NU2M_LUMTE ;
DR   P92660, NU2M_MACRO ;  Q38PS1, NU2M_MAMPR ;  Q2TGY3, NU2M_MARFA ;
DR   P26846, NU2M_MARPO ;  Q2TGY2, NU2M_MARZI ;  Q330E9, NU2M_MEGSP ;
DR   Q5QSA4, NU2M_METNU ;  O47495, NU2M_METSE ;  Q330D6, NU2M_MIMCR ;
DR   Q330E4, NU2M_MOLAE ;  Q330E5, NU2M_MORBE ;  P03893, NU2M_MOUSE ;
DR   Q85PS1, NU2M_MUNMN ;  Q2TGY1, NU2M_MUSKA ;  Q2TQ13, NU2M_MYOKI ;
DR   Q330C4, NU2M_MYOSI ;  Q00229, NU2M_MYTED ;  O21078, NU2M_MYXGL ;
DR   Q85PQ3, NU2M_NANBI ;  Q2TGY4, NU2M_NASNA ;  Q330B4, NU2M_NATST ;
DR   Q330B3, NU2M_NATTU ;  Q35140, NU2M_NEUCR ;  Q330A5, NU2M_NYCAE ;
DR   Q330A4, NU2M_NYCAL ;  Q330C3, NU2M_NYCAR ;  P93401, NU2M_OENBE ;
DR   P48175, NU2M_ONCMY ;  Q36451, NU2M_ORNAN ;  Q71MY2, NU2M_ORYTA ;
DR   Q9T9X1, NU2M_PANPA ;  O21798, NU2M_PANTR ;  Q9ZXY3, NU2M_PAPHA ;
DR   Q85PQ0, NU2M_PARHE ;  P12771, NU2M_PARLI ;  Q330A3, NU2M_PARRP ;
DR   P15577, NU2M_PARTE ;  O79671, NU2M_PELSU ;  Q330H2, NU2M_PERKA ;
DR   Q330H1, NU2M_PERMC ;  Q35535, NU2M_PETMA ;  Q00540, NU2M_PHOVI ;
DR   P48906, NU2M_PICCA ;  O79875, NU2M_PIG   ;  P24996, NU2M_PISOC ;
DR   P15578, NU2M_PODAN ;  Q95910, NU2M_POLOR ;  P92691, NU2M_PONAB ;
DR   Q9T9X8, NU2M_PONPY ;  Q2TGY5, NU2M_POTFL ;  Q330A0, NU2M_PTEPU ;
DR   Q32ZZ9, NU2M_PTERO ;  O79428, NU2M_RABIT ;  P16673, NU2M_RANCA ;
DR   P11662, NU2M_RAT   ;  Q3T4F3, NU2M_RHIOR ;  O99817, NU2M_RHISA ;
DR   Q96061, NU2M_RHIUN ;  Q330H0, NU2M_RHYNA ;  Q330G9, NU2M_SACBI ;
DR   Q330G8, NU2M_SACLE ;  Q35924, NU2M_SALSA ;  O21409, NU2M_SCYCA ;
DR   O78748, NU2M_SHEEP ;  Q9ZZ53, NU2M_SQUAC ;  O21398, NU2M_STRCA ;
DR   P15549, NU2M_STRPU ;  Q2TQ12, NU2M_SUNET ;  Q85PQ2, NU2M_SURSU ;
DR   Q32ZZ5, NU2M_SYCAU ;  Q2TQ17, NU2M_SYLGA ;  Q2TQ20, NU2M_SYLJO ;
DR   Q2TQ19, NU2M_SYLLU ;  Q2TQ18, NU2M_SYLME ;  Q2TQ15, NU2M_SYLOL ;
DR   Q4JQI6, NU2M_TETNG ;  Q32ZZ4, NU2M_THONI ;  Q330B2, NU2M_THYTR ;
DR   Q0H8Y9, NU2M_USTMA ;  Q94VJ9, NU2M_VARBA ;  Q94VJ5, NU2M_VARBN ;
DR   Q94VE5, NU2M_VARML ;  Q94V92, NU2M_VARTI ;  Q85PQ1, NU2M_VIVTA ;
DR   Q534D9, NU2M_VULVU ;  P03894, NU2M_XENLA ;  Q9B6C8, NU2M_YARLI ;
DR   Q37382, NU3M_ACACA ;  B0FWD2, NU3M_AEDAE ;  Q3L6W3, NU3M_AILFU ;
DR   P48907, NU3M_ALBCO ;  Q96007, NU3M_ALLCE ;  Q37399, NU3M_ALLMA ;
DR   O47874, NU3M_ALLMI ;  P34850, NU3M_ANOGA ;  P33509, NU3M_ANOQU ;
DR   P34851, NU3M_APILI ;  P92533, NU3M_ARATH ;  P19043, NU3M_ARTSA ;
DR   Q37709, NU3M_ARTSF ;  P24883, NU3M_ASCSU ;  P11991, NU3M_ASTPE ;
DR   A8DQK7, NU3M_AVACL ;  A8DQI7, NU3M_AVAUN ;  O21584, NU3M_BAITA ;
DR   P68307, NU3M_BALMU ;  P68308, NU3M_BALPH ;  O21540, NU3M_BOLLA ;
DR   Q8WAB4, NU3M_BOSIN ;  Q5Y4Q3, NU3M_BOSMU ;  P03898, NU3M_BOVIN ;
DR   P69236, NU3M_BRAFL ;  P69237, NU3M_BRALA ;  P68160, NU3M_BRANA ;
DR   P24895, NU3M_CAEEL ;  O21554, NU3M_CALCL ;  Q9B8D1, NU3M_CANAL ;
DR   Q9ZZ60, NU3M_CANFA ;  Q3L6Y6, NU3M_CANLU ;  P48909, NU3M_CANPA ;
DR   O78686, NU3M_CARAU ;  O03202, NU3M_CERSI ;  P18938, NU3M_CHICK ;
DR   P48910, NU3M_CHOCR ;  P48911, NU3M_CYACA ;  P24974, NU3M_CYPCA ;
DR   Q9MIY3, NU3M_DANRE ;  O21332, NU3M_DASNO ;  A9RAG5, NU3M_DEBHA ;
DR   Q2LCR0, NU3M_DICCI ;  Q37312, NU3M_DICDI ;  P41306, NU3M_DIDMA ;
DR   O79553, NU3M_DINSE ;  P18930, NU3M_DROME ;  P51940, NU3M_DROSU ;
DR   P07705, NU3M_DROYA ;  Q8W9M9, NU3M_DUGDU ;  Q2I3G7, NU3M_ELEMA ;
DR   O21549, NU3M_ELITY ;  P15956, NU3M_EMENI ;  P92482, NU3M_EQUAS ;
DR   Q34522, NU3M_FASHE ;  P48912, NU3M_FELCA ;  P34192, NU3M_FORLA ;
DR   P15957, NU3M_GADMO ;  Q9T9Y5, NU3M_GORGO ;  O21610, NU3M_HABLO ;
DR   P38600, NU3M_HALGR ;  P60159, NU3M_HELAN ;  Q9ZZY4, NU3M_HIPAM ;
DR   P48654, NU3M_HORSE ;  P03897, NU3M_HUMAN ;  Q95708, NU3M_HYLLA ;
DR   O21598, NU3M_ISTPI ;  O03171, NU3M_LATCH ;  Q8HQB1, NU3M_LEMCA ;
DR   Q36422, NU3M_LOCMI ;  O47476, NU3M_LOLBL ;  Q2I3F4, NU3M_LOXAF ;
DR   Q34950, NU3M_LUMTE ;  P92666, NU3M_MACRO ;  P16265, NU3M_MAIZE ;
DR   Q38PR5, NU3M_MAMPR ;  P26847, NU3M_MARPO ;  Q35100, NU3M_METSE ;
DR   O21519, NU3M_MICPE ;  P03899, NU3M_MOUSE ;  Q00568, NU3M_MYTED ;
DR   Q9G2X1, NU3M_MYXGL ;  O21572, NU3M_NELNE ;  O21578, NU3M_NEOFL ;
DR   O21575, NU3M_NEOLE ;  Q35141, NU3M_NEUCR ;  O21543, NU3M_NOTED ;
DR   O21587, NU3M_OCHNU ;  P18630, NU3M_OENBE ;  P20686, NU3M_ONCGO ;
DR   Q35262, NU3M_ONCKE ;  P20687, NU3M_ONCKI ;  Q37108, NU3M_ONCMA ;
DR   P11629, NU3M_ONCMY ;  P20688, NU3M_ONCNE ;  P25707, NU3M_ONCTS ;
DR   O21595, NU3M_ONYLE ;  Q36456, NU3M_ORNAN ;  O21560, NU3M_ORYPA ;
DR   O21601, NU3M_OSGBA ;  P27062, NU3M_PANGI ;  Q9T9W7, NU3M_PANPA ;
DR   Q9T9V8, NU3M_PANTR ;  Q9ZXX7, NU3M_PAPHA ;  P12774, NU3M_PARLI ;
DR   P92817, NU3M_PAROL ;  P15579, NU3M_PARTE ;  O21613, NU3M_PERBO ;
DR   O21604, NU3M_PERER ;  Q95881, NU3M_PERGO ;  Q95891, NU3M_PERMA ;
DR   Q95897, NU3M_PERME ;  O21607, NU3M_PERMX ;  Q95921, NU3M_PERPL ;
DR   Q96114, NU3M_PERSJ ;  Q95928, NU3M_PERSL ;  Q35540, NU3M_PETMA ;
DR   O21513, NU3M_PHOSU ;  Q00541, NU3M_PHOVI ;  O21546, NU3M_PHYDA ;
DR   P48913, NU3M_PICCA ;  O79880, NU3M_PIG   ;  Q36664, NU3M_PINSY ;
DR   P24997, NU3M_PISOC ;  Q36518, NU3M_PLASU ;  P15580, NU3M_PODAN ;
DR   O21616, NU3M_PODFL ;  Q95915, NU3M_POLOR ;  P92697, NU3M_PONAB ;
DR   Q9T9X5, NU3M_PONPY ;  O99978, NU3M_PORPU ;  Q37625, NU3M_PROWI ;
DR   O79434, NU3M_RABIT ;  P68159, NU3M_RAPSA ;  P05506, NU3M_RAT   ;
DR   O21273, NU3M_RECAM ;  O21569, NU3M_REIAU ;  O21592, NU3M_REIFU ;
DR   O21590, NU3M_REIME ;  Q94P36, NU3M_RHIPI ;  O99823, NU3M_RHISA ;
DR   Q96066, NU3M_RHIUN ;  Q35929, NU3M_SALSA ;  O03252, NU3M_SALTR ;
DR   O63850, NU3M_SARGL ;  O21581, NU3M_SCOTE ;  O79408, NU3M_SCYCA ;
DR   O78753, NU3M_SHEEP ;  O21566, NU3M_SIGHI ;  O21563, NU3M_SIGOC ;
DR   O99869, NU3M_SOLTU ;  Q9ZZ47, NU3M_SQUAC ;  O79102, NU3M_STRCA ;
DR   P15550, NU3M_STRPU ;  Q4JQI0, NU3M_TETNG ;  Q0H8Y8, NU3M_USTMA ;
DR   P60160, NU3M_WHEAT ;  P03900, NU3M_XENLA ;  Q9B6C7, NU3M_YARLI ;
DR   Q37379, NU4LM_ACACA;  Q71RU5, NU4LM_ACIJB;  B0FWD5, NU4LM_AEDAE;
DR   Q3L6W1, NU4LM_AILFU;  P48928, NU4LM_ALBCO;  Q37403, NU4LM_ALLMA;
DR   Q955T4, NU4LM_ALLTR;  P34858, NU4LM_ANOGA;  P33512, NU4LM_ANOQU;
DR   Q7YEL1, NU4LM_AOTTR;  P34859, NU4LM_APILI;  Q04614, NU4LM_ARATH;
DR   Q679A2, NU4LM_ARCAU;  Q8M154, NU4LM_ARCFO;  Q08HJ3, NU4LM_ARCPU;
DR   Q08HF4, NU4LM_ARCTO;  O99602, NU4LM_ARTJA;  P19049, NU4LM_ARTSA;
DR   Q37751, NU4LM_ARTSF;  P24874, NU4LM_ASCSU;  Q5YF91, NU4LM_ASPNG;
DR   Q5S589, NU4LM_ASPTU;  Q33821, NU4LM_ASTPE;  A8DQK8, NU4LM_AVACL;
DR   Q9B8T9, NU4LM_AVALA;  Q05F85, NU4LM_AVAOC;  A8DQI8, NU4LM_AVAUN;
DR   Q69B66, NU4LM_BALBN;  Q598Z5, NU4LM_BALBO;  P41301, NU4LM_BALMU;
DR   Q70S32, NU4LM_BALMY;  Q25CE8, NU4LM_BALOM;  P24976, NU4LM_BALPH;
DR   Q70RV4, NU4LM_BERBI;  Q6EMS3, NU4LM_BOSIN;  Q5Y4Q2, NU4LM_BOSMU;
DR   P03902, NU4LM_BOVIN;  P69238, NU4LM_BRAFL;  P69239, NU4LM_BRALA;
DR   Q58F86, NU4LM_BRATR;  Q8HEB9, NU4LM_CAEBR;  P24886, NU4LM_CAEEL;
DR   Q70XH7, NU4LM_CAEFU;  O21783, NU4LM_CALLC;  Q7GF83, NU4LM_CALMU;
DR   Q08HL9, NU4LM_CALUR;  Q9B8D0, NU4LM_CANAL;  Q9ZZ59, NU4LM_CANFA;
DR   Q1HK43, NU4LM_CANLA;  Q3L6Y4, NU4LM_CANLU;  P48929, NU4LM_CANPA;
DR   Q7YBC1, NU4LM_CAPHI;  Q70S19, NU4LM_CAPMR;  P67783, NU4LM_CARAU;
DR   Q94ZL2, NU4LM_CEBAL;  Q34049, NU4LM_CERCA;  Q2V091, NU4LM_CEREL;
DR   Q1AL67, NU4LM_CERSA;  O03203, NU4LM_CERSI;  Q09EG3, NU4LM_CERUS;
DR   Q9G3R5, NU4LM_CHATU;  Q05F77, NU4LM_CHEME;  P18942, NU4LM_CHICK;
DR   Q1HV35, NU4LM_CHITR;  Q1HV38, NU4LM_CHIVL;  Q50DL2, NU4LM_CHLAE;
DR   P48930, NU4LM_CHOCR;  Q58F73, NU4LM_CHODI;  Q7Y8I6, NU4LM_CHRAS;
DR   Q15GM1, NU4LM_COLBA;  Q5BU77, NU4LM_COLGU;  Q5G7X0, NU4LM_CRORS;
DR   Q8HHD3, NU4LM_CRYPA;  P67784, NU4LM_CYPCA;  Q679A8, NU4LM_CYSCR;
DR   Q1MWH8, NU4LM_DACTR;  Q9MIY2, NU4LM_DANRE;  Q32UT4, NU4LM_DASHA;
DR   O21333, NU4LM_DASNO;  Q94NY9, NU4LM_DAUMA;  A9RAH1, NU4LM_DEBHA;
DR   Q69B76, NU4LM_DELLE;  P0C5X9, NU4LM_DICCI;  Q9XK79, NU4LM_DICDI;
DR   P41307, NU4LM_DIDMA;  O79554, NU4LM_DINSE;  Q1MWK4, NU4LM_DISPE;
DR   P18934, NU4LM_DROME;  Q9T4R3, NU4LM_DRONF;  P07708, NU4LM_DROYA;
DR   Q8W9M8, NU4LM_DUGDU;  Q953L2, NU4LM_ECHGY;  Q9G385, NU4LM_ECHTE;
DR   Q1HV41, NU4LM_ECTAL;  Q9B987, NU4LM_ELACE;  Q2I3G6, NU4LM_ELEMA;
DR   Q953I6, NU4LM_EPIFU;  P92483, NU4LM_EQUAS;  Q08H76, NU4LM_ERIBA;
DR   Q70S06, NU4LM_ESCGI;  Q69B78, NU4LM_EUBAS;  Q69B80, NU4LM_EUBGL;
DR   Q598U3, NU4LM_EUBJA;  Q94XZ5, NU4LM_EULCO;  Q7IT44, NU4LM_EULMO;
DR   Q94XZ1, NU4LM_EULRU;  Q8LX40, NU4LM_EUMJU;  P48931, NU4LM_FELCA;
DR   P34193, NU4LM_FORLA;  P23633, NU4LM_GADMO;  Q1EG09, NU4LM_GALPY;
DR   Q85DA0, NU4LM_GALSE;  Q8LX57, NU4LM_GALVR;  Q34572, NU4LM_GORGO;
DR   Q679A1, NU4LM_GULGU;  P68309, NU4LM_HALGR;  Q8HC89, NU4LM_HAPAU;
DR   Q8HC87, NU4LM_HAPSI;  Q7Y8G0, NU4LM_HEMAU;  Q5I195, NU4LM_HERJA;
DR   Q9ZZY3, NU4LM_HIPAM;  P48658, NU4LM_HORSE;  P03901, NU4LM_HUMAN;
DR   Q9B985, NU4LM_HYDIN;  Q679B8, NU4LM_HYDLE;  Q95709, NU4LM_HYLLA;
DR   Q70RW7, NU4LM_HYPAP;  Q70RS8, NU4LM_INIGE;  Q9B2G1, NU4LM_ISOMA;
DR   Q70RY0, NU4LM_KOGBR;  Q70RQ2, NU4LM_LAGAL;  Q08GM0, NU4LM_LAGFA;
DR   Q1MWF2, NU4LM_LAGHI;  Q9MEI2, NU4LM_LAMPA;  O03172, NU4LM_LATCH;
DR   Q94Y87, NU4LM_LEMCA;  Q8LWW8, NU4LM_LEPEU;  Q05EQ4, NU4LM_LEPMS;
DR   Q00GQ9, NU4LM_LEPSH;  Q00HT4, NU4LM_LEPSL;  Q679B6, NU4LM_LEPWE;
DR   Q2YG58, NU4LM_LIPVE;  Q679C1, NU4LM_LOBCR;  Q36423, NU4LM_LOCMI;
DR   Q3L6S8, NU4LM_LONCN;  Q9TA21, NU4LM_LOXAF;  Q34948, NU4LM_LUMTE;
DR   Q3L708, NU4LM_LYNCA;  Q9XL66, NU4LM_MACBR;  Q7J3C3, NU4LM_MACFA;
DR   Q9XK21, NU4LM_MACHE;  Q5QS32, NU4LM_MACLA;  Q9XJY3, NU4LM_MACMR;
DR   Q6IYH0, NU4LM_MACMU;  Q9XL45, NU4LM_MACNG;  Q9XL48, NU4LM_MACNR;
DR   Q9XL62, NU4LM_MACOC;  Q7J3B5, NU4LM_MACPG;  Q8LWU8, NU4LM_MACPR;
DR   P92667, NU4LM_MACRO;  Q9XL36, NU4LM_MACSY;  Q38PR4, NU4LM_MAMPR;
DR   Q8LWT4, NU4LM_MANTE;  Q3L6T9, NU4LM_MARAM;  P26851, NU4LM_MARPO;
DR   Q69B84, NU4LM_MEGNO;  Q3L6V0, NU4LM_MEPME;  Q1HUY4, NU4LM_MESMC;
DR   Q5QS97, NU4LM_METNU;  O47492, NU4LM_METSE;  Q591P2, NU4LM_MICGI;
DR   Q591V2, NU4LM_MICJO;  Q591Y0, NU4LM_MICMI;  Q00GF0, NU4LM_MICMM;
DR   O21520, NU4LM_MICPE;  Q94Q33, NU4LM_MICRA;  Q591M6, NU4LM_MICSI;
DR   Q591Y8, NU4LM_MICSM;  Q679B3, NU4LM_MIRAN;  Q94PA4, NU4LM_MIRCO;
DR   Q679B2, NU4LM_MIRLE;  Q7Y8E7, NU4LM_MOGWO;  Q65CI5, NU4LM_MONDO;
DR   Q679B0, NU4LM_MONMN;  Q70RN9, NU4LM_MONMO;  Q6U7Y2, NU4LM_MONPE;
DR   Q679B1, NU4LM_MONSC;  P03903, NU4LM_MOUSE;  Q9B1C5, NU4LM_MUNCR;
DR   Q7IVV3, NU4LM_MUNFE;  Q7IVV2, NU4LM_MUNGO;  Q9B996, NU4LM_MUNVU;
DR   Q679A0, NU4LM_MUSVI;  Q58F60, NU4LM_MYSTU;  Q00230, NU4LM_MYTED;
DR   Q9G2X0, NU4LM_MYXGL;  Q15GR0, NU4LM_NASLA;  Q08HG7, NU4LM_NEOCN;
DR   Q072K5, NU4LM_NEONE;  P05509, NU4LM_NEUCR;  Q5QRZ3, NU4LM_NOTTY;
DR   Q94Z64, NU4LM_NYCCO;  O21535, NU4LM_NYCSU;  Q953J9, NU4LM_OCHCO;
DR   Q70UT9, NU4LM_OCHPR;  Q8LWS1, NU4LM_ODORR;  Q679B9, NU4LM_OMMRO;
DR   P69306, NU4LM_ONCCL;  P69303, NU4LM_ONCGO;  P69304, NU4LM_ONCKI;
DR   Q37131, NU4LM_ONCMA;  P69302, NU4LM_ONCMY;  P69305, NU4LM_ONCNE;
DR   P69307, NU4LM_ONCTS;  Q36457, NU4LM_ORNAN;  Q9XMJ3, NU4LM_ORYAF;
DR   O21558, NU4LM_ORYAL;  Q679A3, NU4LM_OTABY;  Q85DA4, NU4LM_OTOCR;
DR   Q7HLD2, NU4LM_OVICA;  O21517, NU4LM_OXYRU;  Q679A7, NU4LM_PAGGO;
DR   Q3LR84, NU4LM_PANHO;  Q35588, NU4LM_PANPA;  Q37809, NU4LM_PANTR;
DR   Q9ZXX6, NU4LM_PAPHA;  P12773, NU4LM_PARLI;  Q6V9E0, NU4LM_PENMQ;
DR   Q5QS19, NU4LM_PERGU;  Q1MWG5, NU4LM_PETBR;  Q35541, NU4LM_PETMA;
DR   Q1MWJ1, NU4LM_PHACI;  Q5QS58, NU4LM_PHATA;  Q1MWD9, NU4LM_PHAVS;
DR   Q08H50, NU4LM_PHOFA;  Q08GV9, NU4LM_PHOHI;  Q08HI0, NU4LM_PHOHO;
DR   Q679A5, NU4LM_PHOLR;  Q70RM6, NU4LM_PHOPH;  Q08GY5, NU4LM_PHOSI;
DR   O21514, NU4LM_PHOSU;  P68310, NU4LM_PHOVI;  Q37598, NU4LM_PHYIN;
DR   Q9MES8, NU4LM_PHYMC;  Q36903, NU4LM_PICCA;  P56632, NU4LM_PIG  ;
DR   Q94YC5, NU4LM_PIPAB;  P25000, NU4LM_PISOC;  Q1HUZ6, NU4LM_PLABC;
DR   Q1HUZ9, NU4LM_PLADO;  Q1HV02, NU4LM_PLAHE;  Q70RU1, NU4LM_PLAMN;
DR   P20680, NU4LM_PODAN;  Q95916, NU4LM_POLOR;  P61795, NU4LM_PONAB;
DR   Q70RR5, NU4LM_PONBL;  P61796, NU4LM_PONPY;  Q5QS06, NU4LM_POTTR;
DR   Q15GP7, NU4LM_PREME;  Q7Y8J9, NU4LM_PROCA;  Q9B8T5, NU4LM_PRODD;
DR   Q3L6Q6, NU4LM_PROLO;  Q7ISH5, NU4LM_PROTA;  Q37627, NU4LM_PROWI;
DR   Q5QS45, NU4LM_PSEPE;  Q9G6M7, NU4LM_PTEDA;  Q9G3S8, NU4LM_PTESA;
DR   Q3L6Z6, NU4LM_PUMCO;  Q08GZ8, NU4LM_PUSCA;  O79435, NU4LM_RABIT;
DR   Q2V0A4, NU4LM_RANTA;  P05507, NU4LM_RAT  ;  Q7I5M1, NU4LM_RHIMO;
DR   Q94N24, NU4LM_RHIPI;  Q1HV56, NU4LM_RHIPM;  O99826, NU4LM_RHISA;
DR   Q96067, NU4LM_RHIUN;  Q70XJ0, NU4LM_RHYRA;  Q401Y8, NU4LM_ROUAE;
DR   Q9ZZM5, NU4LM_SALSA;  O63851, NU4LM_SARGL;  Q94ZI2, NU4LM_SCHCO;
DR   O79409, NU4LM_SCYCA;  Q15GS3, NU4LM_SEMEN;  O78754, NU4LM_SHEEP;
DR   O21567, NU4LM_SIGHI;  Q32US1, NU4LM_SMICR;  Q5QS84, NU4LM_SMIDO;
DR   Q94YD6, NU4LM_SORUN;  Q9ZZ46, NU4LM_SQUAC;  Q1HV53, NU4LM_STERU;
DR   O21405, NU4LM_STRCA;  P15554, NU4LM_STRPU;  Q1HV59, NU4LM_STULI;
DR   Q9MJA8, NU4LM_TALEU;  Q8LWN4, NU4LM_TAMTE;  Q8SJ54, NU4LM_TARBA;
DR   Q5QS71, NU4LM_TARRO;  Q3L6R7, NU4LM_TAXTA;  Q4JQH9, NU4LM_TETNG;
DR   Q70XG4, NU4LM_THYEL;  Q5BU90, NU4LM_TRAOB;  O21787, NU4LM_TRAPO;
DR   Q36832, NU4LM_TRIPI;  Q8SHP8, NU4LM_TRIRE;  Q01562, NU4LM_TRIRU;
DR   Q952R8, NU4LM_TRIVU;  Q1HV11, NU4LM_UROBI;  Q7Y8D5, NU4LM_UROTA;
DR   Q8SJJ1, NU4LM_URSAM;  Q8SJH9, NU4LM_URSAR;  Q8SJG7, NU4LM_URSMA;
DR   Q3L6P5, NU4LM_URSML;  Q0H8X1, NU4LM_USTMA;  Q1HV29, NU4LM_VAMBI;
DR   Q1HV23, NU4LM_VAMBR;  Q1HV05, NU4LM_VAMCA;  Q1HUX8, NU4LM_VAMME;
DR   Q1HV14, NU4LM_VAMNY;  Q1HUX2, NU4LM_VAMPU;  Q1HUW0, NU4LM_VAMTH;
DR   Q8HBG2, NU4LM_VARVR;  Q8HBG1, NU4LM_VARVV;  Q953H3, NU4LM_VOLKI;
DR   Q8W9B6, NU4LM_VOMUR;  Q3L6X2, NU4LM_VULLA;  Q08GU6, NU4LM_VULVU;
DR   P03904, NU4LM_XENLA;  Q9B6D4, NU4LM_YARLI;  Q5ZNA2, NU4LM_ZAGBR;
DR   Q08HK6, NU4LM_ZALCA;  Q69B86, NU4LM_ZIPCA;  Q37375, NU4M_ACACA ;
DR   Q1HR20, NU4M_AEDAE ;  P92623, NU4M_AGKAC ;  P92492, NU4M_AGKCO ;
DR   P92503, NU4M_AGKPI ;  P92613, NU4M_AGKRH ;  P48914, NU4M_ALBCO ;
DR   P51898, NU4M_ANOAR ;  P34852, NU4M_ANOGA ;  P33511, NU4M_ANOQU ;
DR   P34853, NU4M_APILI ;  P93313, NU4M_ARATH ;  P34941, NU4M_ARBLI ;
DR   P19046, NU4M_ARTSA ;  Q37711, NU4M_ARTSF ;  P24880, NU4M_ASCSU ;
DR   P03913, NU4M_ASPAM ;  P11992, NU4M_ASTPE ;  O03692, NU4M_ATRNM ;
DR   O03695, NU4M_ATRPI ;  A8DQK9, NU4M_AVACL ;  A8DQI9, NU4M_AVAUN ;
DR   P92494, NU4M_AZEFE ;  P41298, NU4M_BALMU ;  P24975, NU4M_BALPH ;
DR   Q576B5, NU4M_BOSIN ;  Q5Y4Q1, NU4M_BOSMU ;  O03697, NU4M_BOTAS ;
DR   O03698, NU4M_BOTBI ;  O03699, NU4M_BOTER ;  O03700, NU4M_BOTLA ;
DR   O03701, NU4M_BOTSC ;  P03910, NU4M_BOVIN ;  Q04050, NU4M_BRACM ;
DR   O47423, NU4M_BRAFL ;  O79421, NU4M_BRALA ;  P24892, NU4M_CAEEL ;
DR   Q34076, NU4M_CAICR ;  Q9B8C8, NU4M_CANAL ;  Q9ZZ58, NU4M_CANFA ;
DR   Q3L6Y5, NU4M_CANLU ;  Q598S9, NU4M_CAPMR ;  O78687, NU4M_CARAU ;
DR   O03707, NU4M_CAURH ;  Q34048, NU4M_CERCA ;  O03703, NU4M_CERGO ;
DR   O03204, NU4M_CERSI ;  P18939, NU4M_CHICK ;  P20113, NU4M_CHLRE ;
DR   P48915, NU4M_CHOCR ;  O03702, NU4M_CROAD ;  O03704, NU4M_CROLE ;
DR   O03710, NU4M_CROOO ;  O03780, NU4M_CRYAB ;  O03792, NU4M_CRYCN ;
DR   Q9MIY1, NU4M_DANRE ;  O21334, NU4M_DASNO ;  A9RAH8, NU4M_DEBHA ;
DR   Q2LCP7, NU4M_DICCI ;  O21047, NU4M_DICDI ;  P41308, NU4M_DIDMA ;
DR   O79555, NU4M_DINSE ;  P18931, NU4M_DROME ;  P07707, NU4M_DROYA ;
DR   Q8W9M7, NU4M_DUGDU ;  Q2I3G5, NU4M_ELEMA ;  P03914, NU4M_EMENI ;
DR   P92484, NU4M_EQUAS ;  P48916, NU4M_FELCA ;  P34194, NU4M_FORLA ;
DR   P55781, NU4M_GADMO ;  O03726, NU4M_GLOBL ;  O03727, NU4M_GLOIT ;
DR   P03907, NU4M_GORGO ;  P38601, NU4M_HALGR ;  Q9ZZY2, NU4M_HIPAM ;
DR   P48655, NU4M_HORSE ;  P03905, NU4M_HUMAN ;  P03909, NU4M_HYLLA ;
DR   O03733, NU4M_HYPHY ;  P92649, NU4M_LACMU ;  O03173, NU4M_LATCH ;
DR   Q34878, NU4M_LEMCA ;  Q85DA7, NU4M_LEPST ;  Q36424, NU4M_LOCMI ;
DR   Q2I3F2, NU4M_LOXAF ;  Q34949, NU4M_LUMTE ;  P50664, NU4M_MACFA ;
DR   P92668, NU4M_MACRO ;  Q38PR3, NU4M_MAMPR ;  P26848, NU4M_MARPO ;
DR   O47497, NU4M_METSE ;  O21521, NU4M_MICPE ;  Q591M5, NU4M_MICSI ;
DR   Q591Y7, NU4M_MICSM ;  P03911, NU4M_MOUSE ;  Q00231, NU4M_MYTED ;
DR   Q9G2W9, NU4M_MYXGL ;  P11631, NU4M_ONCMY ;  Q36458, NU4M_ORNAN ;
DR   P92681, NU4M_OVOOK ;  Q9T9W6, NU4M_PANPA ;  P03906, NU4M_PANTR ;
DR   P12775, NU4M_PARLI ;  P15581, NU4M_PARTE ;  O79677, NU4M_PELSU ;
DR   Q35542, NU4M_PETMA ;  O21515, NU4M_PHOSU ;  Q00506, NU4M_PHOVI ;
DR   P48917, NU4M_PICCA ;  O79881, NU4M_PIG   ;  P24998, NU4M_PISOC ;
DR   P15582, NU4M_PODAN ;  Q95917, NU4M_POLOR ;  P92698, NU4M_PONAB ;
DR   P03908, NU4M_PONPY ;  O03763, NU4M_PORHY ;  O03772, NU4M_PORNA ;
DR   O03773, NU4M_POROP ;  P92793, NU4M_PROEL ;  P92794, NU4M_PROFL ;
DR   Q37617, NU4M_PROWI ;  O79436, NU4M_RABIT ;  P05508, NU4M_RAT   ;
DR   O99825, NU4M_RHISA ;  Q96068, NU4M_RHIUN ;  Q9ZZM4, NU4M_SALSA ;
DR   O79410, NU4M_SCYCA ;  O78755, NU4M_SHEEP ;  P50660, NU4M_SIMVI ;
DR   O03778, NU4M_SISMI ;  Q9ZZ45, NU4M_SQUAC ;  O21406, NU4M_STRCA ;
DR   P15551, NU4M_STRPU ;  Q8W9G4, NU4M_TACAC ;  Q36150, NU4M_TARSY ;
DR   Q4JQH8, NU4M_TETNG ;  Q36834, NU4M_TRIRU ;  O03807, NU4M_TROWA ;
DR   Q0H8X6, NU4M_USTMA ;  P92759, NU4M_VIRST ;  P27572, NU4M_WHEAT ;
DR   P03912, NU4M_XENLA ;  Q9B6D6, NU4M_YARLI ;  Q5ZNA1, NU4M_ZAGBR ;
DR   Q5DUY0, NU5H_NYCOV ;  Q37372, NU5M_ACACA ;  B0FWD3, NU5M_AEDAE ;
DR   P48918, NU5M_ALBCO ;  P50365, NU5M_ALLMA ;  P51899, NU5M_ANOAR ;
DR   P34854, NU5M_ANOGA ;  Q31696, NU5M_ANOQN ;  P33510, NU5M_ANOQU ;
DR   Q31651, NU5M_ANSCE ;  P34855, NU5M_APILI ;  P29388, NU5M_ARATH ;
DR   Q33753, NU5M_ARBLI ;  P19047, NU5M_ARTSA ;  Q37710, NU5M_ARTSF ;
DR   P24884, NU5M_ASCSU ;  Q6QU67, NU5M_ASPNG ;  P11993, NU5M_ASTPE ;
DR   P41299, NU5M_BALMU ;  P24978, NU5M_BALPH ;  Q576B4, NU5M_BOSIN ;
DR   P03920, NU5M_BOVIN ;  O47430, NU5M_BRAFL ;  O79422, NU5M_BRALA ;
DR   P24896, NU5M_CAEEL ;  Q9B8C9, NU5M_CANAL ;  Q9ZZ57, NU5M_CANFA ;
DR   Q1HK80, NU5M_CANLU ;  P48919, NU5M_CANPA ;  O78688, NU5M_CARAU ;
DR   Q34052, NU5M_CERCA ;  O03205, NU5M_CERSI ;  P18940, NU5M_CHICK ;
DR   Q94RJ2, NU5M_CHIMO ;  P08739, NU5M_CHLRE ;  P48920, NU5M_CHOCR ;
DR   Q85T01, NU5M_CRYNV ;  Q8HHD2, NU5M_CRYPA ;  P24979, NU5M_CYPCA ;
DR   Q9MIY0, NU5M_DANRE ;  O21335, NU5M_DASNO ;  A9RAH0, NU5M_DEBHA ;
DR   Q2LCP6, NU5M_DICCI ;  Q34313, NU5M_DICDI ;  P41309, NU5M_DIDMA ;
DR   O79556, NU5M_DINSE ;  P18932, NU5M_DROME ;  P07706, NU5M_DROYA ;
DR   Q8W9M6, NU5M_DUGDU ;  Q2I3G4, NU5M_ELEMA ;  P11628, NU5M_EMENI ;
DR   Q953I4, NU5M_EPIFU ;  P92485, NU5M_EQUAS ;  P48921, NU5M_FELCA ;
DR   P34195, NU5M_FORLA ;  P55782, NU5M_GADMO ;  O47815, NU5M_GEOPE ;
DR   O63908, NU5M_GLIGL ;  P03917, NU5M_GORGO ;  P38602, NU5M_HALGR ;
DR   Q9ZZY1, NU5M_HIPAM ;  P48656, NU5M_HORSE ;  P03915, NU5M_HUMAN ;
DR   P03919, NU5M_HYLLA ;  O03174, NU5M_LATCH ;  P15583, NU5M_LEITA ;
DR   Q34879, NU5M_LEMCA ;  Q36428, NU5M_LOCMI ;  Q9TA19, NU5M_LOXAF ;
DR   Q34947, NU5M_LUMTE ;  P50665, NU5M_MACFA ;  P92669, NU5M_MACRO ;
DR   Q36284, NU5M_MAIZE ;  Q38PR2, NU5M_MAMPR ;  P26849, NU5M_MARPO ;
DR   Q35099, NU5M_METSE ;  P03921, NU5M_MOUSE ;  Q00232, NU5M_MYTED ;
DR   Q9G2W8, NU5M_MYXGL ;  P05510, NU5M_NEUCR ;  P10330, NU5M_OENBE ;
DR   P48176, NU5M_ONCMY ;  Q36459, NU5M_ORNAN ;  P03916, NU5M_PANPA ;
DR   Q35648, NU5M_PANTR ;  Q95885, NU5M_PAPHA ;  P12776, NU5M_PARLI ;
DR   P15584, NU5M_PARTE ;  Q35639, NU5M_PEA   ;  O79678, NU5M_PELSU ;
DR   Q6V9D9, NU5M_PENMQ ;  Q35543, NU5M_PETMA ;  Q00542, NU5M_PHOVI ;
DR   P50366, NU5M_PHYIN ;  Q37024, NU5M_PICCA ;  Q9TDR1, NU5M_PIG   ;
DR   P24999, NU5M_PISOC ;  P20679, NU5M_PODAN ;  Q95918, NU5M_POLOR ;
DR   P92699, NU5M_PONAB ;  P03918, NU5M_PONPY ;  O79437, NU5M_RABIT ;
DR   P11661, NU5M_RAT   ;  Q9ZYM7, NU5M_RHISA ;  P50367, NU5M_RHIST ;
DR   Q96069, NU5M_RHIUN ;  Q76LN2, NU5M_ROUAM ;  Q9ZZM3, NU5M_SALSA ;
DR   P50368, NU5M_SCHCO ;  O79411, NU5M_SCYCA ;  O78756, NU5M_SHEEP ;
DR   Q9ZZ44, NU5M_SQUAC ;  Q35813, NU5M_STRCA ;  Q35832, NU5M_STRFN ;
DR   P15552, NU5M_STRPU ;  Q36151, NU5M_TARSY ;  Q4JQH7, NU5M_TETNG ;
DR   Q8SHP7, NU5M_TRIRE ;  Q01561, NU5M_TRIRU ;  P04540, NU5M_TRYBB ;
DR   Q0H8X0, NU5M_USTMA ;  Q37680, NU5M_WHEAT ;  P03922, NU5M_XENLA ;
DR   Q9B6D3, NU5M_YARLI ;  Q37371, NU6M_ACACA ;  B0FWD6, NU6M_AEDAE ;
DR   P43189, NU6M_AETCR ;  P43190, NU6M_AETPU ;  P43191, NU6M_AETPY ;
DR   P48922, NU6M_ALBCO ;  Q08084, NU6M_ALBTU ;  P43193, NU6M_ALCTO ;
DR   P43192, NU6M_ALLAL ;  Q06059, NU6M_ANAPL ;  Q33635, NU6M_ANOAL ;
DR   P34856, NU6M_ANOGA ;  P33513, NU6M_ANOQU ;  P34857, NU6M_APILI ;
DR   P60497, NU6M_ARATH ;  P19048, NU6M_ARTSA ;  Q37712, NU6M_ARTSF ;
DR   P24873, NU6M_ASCSU ;  Q33817, NU6M_ASTPE ;  P41300, NU6M_BALMU ;
DR   P24980, NU6M_BALPH ;  Q71PB7, NU6M_BOSIN ;  Q5ULB0, NU6M_BOSMU ;
DR   P03924, NU6M_BOVIN ;  P43194, NU6M_BRABR ;  P60498, NU6M_BRACM ;
DR   P69232, NU6M_BRAFL ;  P69233, NU6M_BRALA ;  P43195, NU6M_BRAMA ;
DR   Q8HEC0, NU6M_CAEBR ;  P24885, NU6M_CAEEL ;  P43196, NU6M_CALMA ;
DR   Q9B8D7, NU6M_CANAL ;  Q9ZZ56, NU6M_CANFA ;  Q1HK79, NU6M_CANLU ;
DR   P48923, NU6M_CANPA ;  O78689, NU6M_CARAU ;  P43197, NU6M_CEPCO ;
DR   P43198, NU6M_CEPGR ;  Q34050, NU6M_CERCA ;  O03206, NU6M_CERSI ;
DR   P18941, NU6M_CHICK ;  P10329, NU6M_CHLRE ;  P48924, NU6M_CHOCR ;
DR   P24981, NU6M_COTJA ;  P48925, NU6M_CYACA ;  P43199, NU6M_CYCPS ;
DR   P24982, NU6M_CYPCA ;  Q9MIX9, NU6M_DANRE ;  O21336, NU6M_DASNO ;
DR   A9RAG2, NU6M_DEBHA ;  Q2LCR2, NU6M_DICCI ;  Q37314, NU6M_DICDI ;
DR   P41315, NU6M_DIDMA ;  O79557, NU6M_DINSE ;  P18933, NU6M_DROME ;
DR   P07709, NU6M_DROYA ;  Q8W9M5, NU6M_DUGDU ;  Q2I3G3, NU6M_ELEMA ;
DR   Q953I3, NU6M_EPIFU ;  P92486, NU6M_EQUAS ;  P48926, NU6M_FELCA ;
DR   P34196, NU6M_FORLA ;  P43200, NU6M_FRAAR ;  P43202, NU6M_FRACI ;
DR   P43201, NU6M_FRACR ;  P55783, NU6M_GADMO ;  Q34573, NU6M_GORGO ;
DR   P38603, NU6M_HALGR ;  Q9ZZY0, NU6M_HIPAM ;  P48657, NU6M_HORSE ;
DR   P03923, NU6M_HUMAN ;  Q95710, NU6M_HYLLA ;  P41322, NU6M_LARCA ;
DR   O03175, NU6M_LATCH ;  Q8LX23, NU6M_LEMCA ;  Q36425, NU6M_LOCMI ;
DR   O47478, NU6M_LOLBL ;  Q9TA18, NU6M_LOXAF ;  Q34944, NU6M_LUMTE ;
DR   P92670, NU6M_MACRO ;  Q38PR1, NU6M_MAMPR ;  P26850, NU6M_MARPO ;
DR   O47498, NU6M_METSE ;  P03925, NU6M_MOUSE ;  Q00570, NU6M_MYTED ;
DR   Q9G2W7, NU6M_MYXGL ;  P48177, NU6M_ONCMY ;  Q36460, NU6M_ORNAN ;
DR   Q9T9W5, NU6M_PANPA ;  Q9T9V6, NU6M_PANTR ;  Q9ZXX5, NU6M_PAPHA ;
DR   P12777, NU6M_PARLI ;  O79679, NU6M_PELSU ;  Q35544, NU6M_PETMA ;
DR   Q00543, NU6M_PHOVI ;  P48927, NU6M_PICCA ;  O79882, NU6M_PIG   ;
DR   P15959, NU6M_PODAN ;  Q95919, NU6M_POLOR ;  P92700, NU6M_PONAB ;
DR   Q9T9X3, NU6M_PONPY ;  Q37626, NU6M_PROWI ;  Q9G6M4, NU6M_PTEDA ;
DR   Q9G3S5, NU6M_PTESA ;  P43203, NU6M_PTYAL ;  O79438, NU6M_RABIT ;
DR   P03926, NU6M_RAT   ;  Q94VK5, NU6M_RHIMO ;  O99827, NU6M_RHISA ;
DR   Q96070, NU6M_RHIUN ;  Q9ZZM2, NU6M_SALSA ;  O63849, NU6M_SARGL ;
DR   O79412, NU6M_SCYCA ;  O78757, NU6M_SHEEP ;  Q9ZZ43, NU6M_SQUAC ;
DR   O21407, NU6M_STRCA ;  P15553, NU6M_STRPU ;  P43204, NU6M_SYNAN ;
DR   P43205, NU6M_SYNHY ;  P43206, NU6M_SYNWU ;  Q8W9G2, NU6M_TACAC ;
DR   Q4JQH6, NU6M_TETNG ;  Q36836, NU6M_TRIRU ;  P43207, NU6M_URIAL ;
DR   P43208, NU6M_URILO ;  Q7Y8D2, NU6M_UROTA ;  Q0H8W8, NU6M_USTMA ;
DR   Q02500, NU6M_WHEAT ;  P03927, NU6M_XENLA ;  Q9B6E9, NU6M_YARLI ;
DR   P25710, NUJM_NEUCR ;  P80268, NUO2_SOLTU ;  P80263, NUO3_SOLTU ;
DR   P80262, NUO5_SOLTU ;  P80729, NUO6_SOLTU ;  P80730, NUO7_SOLTU ;
DR   P80731, NUO8_SOLTU ;  P42116, NURM_NEUCR ;  Q02854, NUXM_NEUCR ;
DR   P19968, NUZM_NEUCR ;  Q57940, Y520_METJA ;
//
ID   1.6.5.4
DE   Monodehydroascorbate reductase (NADH).
CA   NADH + 2 monodehydroascorbate = NAD(+) + 2 ascorbate.
DR   Q9SR59, MDAR1_ARATH;  Q9LK94, MDAR2_ARATH;  Q9S926, MDAR2_SOYBN;
DR   Q9LFA3, MDAR3_ARATH;  Q93WJ8, MDAR4_ARATH;  P83966, MDARF_CUCSA;
DR   P92947, MDARP_ARATH;  Q42711, MDARS_CUCSA;  Q40977, MDAR_PEA   ;
DR   Q43497, MDAR_SOLLC ;  Q84UV8, NEC3_NICLS ;
//
ID   1.6.5.5
DE   NADPH:quinone reductase.
AN   Quinone oxidoreductase.
AN   Zeta-crystallin.
CA   NADPH + 2 quinone = NADP(+) + 2 semiquinone.
CF   Zinc.
CC   -!- Specific for NADPH.
CC   -!- Catalyzes the one-electron reduction of certain quinones, with the
CC       orthoquinones 1,2-naphthoquinone and 9,10-phenanthrenequinone being
CC       the best substrates.
CC   -!- Dicoumarol (cf. EC 1.6.5.2) and nitrofurantoin are competitive
CC       inhibitors with respect to the quinone substrate.
CC   -!- The semiquinone free-radical product may be non-enzymically reduced
CC       to the hydroquinone or oxidized back to quinone in the presence of
CC       O(2).
CC   -!- Abundant in the lens of the eye of some mammalian species.
PR   PROSITE; PDOC00058;
DR   P28304, QOR1_ECOLI ;  P11415, QOR_CAVPO  ;  Q08257, QOR_HUMAN  ;
DR   Q28452, QOR_LAMGU  ;  P42865, QOR_LEIAM  ;  P47199, QOR_MOUSE  ;
DR   Q0MVN8, QOR_PIG    ;  Q5R4S7, QOR_PONAB  ;  P43903, QOR_PSEAE  ;
DR   Q6AYT0, QOR_RAT    ;  P40783, QOR_SALTY  ;  O74489, QOR_SCHPO  ;
DR   P38230, QOR_YEAST  ;
//
ID   1.6.5.6
DE   p-benzoquinone reductase (NADPH).
CA   NADPH + p-benzoquinone = NADP(+) + hydroquinone.
CC   -!- Involved in the 4-nitrophenol degradation pathway in bacteria.
//
ID   1.6.5.7
DE   2-hydroxy-1,4-benzoquinone reductase.
AN   Hydroxybenzoquinone reductase.
CA   2-hydroxy-1,4-benzoquinone + NADH = 1,2,4-trihydroxybenzene + NAD(+).
CF   FMN.
CC   -!- The enzyme differs in substrate speificity from other quinone
CC       reductases.
CC   -!- The enzyme in Burkholderia cepacia is inducible by 2,4,5-
CC       trichlorophenoxyacetate.
//
ID   1.6.5.8
DE   NADH:ubiquinone reductase (Na(+)-transporting).
AN   Na(+)-NQR.
AN   Na(+)-translocating NADH-quinone reductase.
CA   NADH + ubiquinone + n Na(+)(In) = NAD(+) + ubiquinol + n Na(+)(Out).
CF   FAD; FMN; Iron-sulfur; Riboflavin.
//
ID   1.6.5.9
DE   NADH:ubiquinone reductase (non-electrogenic).
AN   Coenzyme Q reductase.
AN   Electron transfer complex I.
AN   NADH(2) dehydrogenase (ubiquinone).
AN   NADH-coenzyme Q oxidoreductase.
AN   NADH-coenzyme Q reductase.
AN   NADH-CoQ oxidoreductase.
AN   NADH-CoQ reductase.
AN   NADH-Q6 oxidoreductase.
AN   NADH-ubiquinone oxidoreductase.
AN   NADH-ubiquinone reductase.
AN   Ubiquinone reductase.
CA   NADH + ubiquinone = NAD(+) + ubiquinol.
CF   FAD.
CC   -!- Occurs in mitochondria of yeast and plants, and in aerobic bacteria.
CC   -!- Has low activity with NADPH.
DR   P32340, NDI1_YEAST ;
//
ID   1.6.6.1
DE   Transferred entry: 1.7.1.1.
//
ID   1.6.6.2
DE   Transferred entry: 1.7.1.2.
//
ID   1.6.6.3
DE   Transferred entry: 1.7.1.3.
//
ID   1.6.6.4
DE   Transferred entry: 1.7.1.4.
//
ID   1.6.6.5
DE   Transferred entry: 1.7.2.1.
//
ID   1.6.6.6
DE   Transferred entry: 1.7.1.5.
//
ID   1.6.6.7
DE   Transferred entry: 1.7.1.6.
//
ID   1.6.6.8
DE   Transferred entry: 1.7.1.7.
//
ID   1.6.6.9
DE   Trimethylamine-N-oxide reductase.
AN   Trimethylamine oxidase.
CA   NADH + trimethylamine N-oxide = NAD(+) + trimethylamine + H(2)O.
PR   PROSITE; PDOC00392;
//
ID   1.6.6.10
DE   Transferred entry: 1.7.1.9.
//
ID   1.6.6.11
DE   Transferred entry: 1.7.1.10.
//
ID   1.6.6.12
DE   Transferred entry: 1.7.1.11.
//
ID   1.6.6.13
DE   Transferred entry: 1.7.1.12.
//
ID   1.6.7.1
DE   Transferred entry: 1.18.1.2.
//
ID   1.6.7.2
DE   Transferred entry: 1.18.1.1.
//
ID   1.6.8.1
DE   Transferred entry: 1.5.1.29.
//
ID   1.6.8.2
DE   Transferred entry: 1.5.1.30.
//
ID   1.6.99.1
DE   NADPH dehydrogenase.
AN   NADPH diaphorase.
CA   NADPH + acceptor = NADP(+) + reduced acceptor.
CF   FMN or FAD.
CC   -!- FMN in yeasts; FAD in plants.
DR   P43084, EBP1_CANAL ;  A7Z6E7, NAMA_BACA2 ;  C3P7Z9, NAMA_BACAA ;
DR   C3L5F3, NAMA_BACAC ;  A0RD27, NAMA_BACAH ;  Q81RK6, NAMA_BACAN ;
DR   B7JKM7, NAMA_BACC0 ;  Q739N4, NAMA_BACC1 ;  B7ITF9, NAMA_BACC2 ;
DR   C1ERH2, NAMA_BACC3 ;  B7HJE9, NAMA_BACC4 ;  B7HNI1, NAMA_BACC7 ;
DR   A7GNY4, NAMA_BACCN ;  B9IY25, NAMA_BACCQ ;  Q81EF6, NAMA_BACCR ;
DR   Q63CC9, NAMA_BACCZ ;  Q9KCT8, NAMA_BACHD ;  Q6HJU1, NAMA_BACHK ;
DR   Q65HN9, NAMA_BACLD ;  A8FEW4, NAMA_BACP2 ;  P54550, NAMA_BACSU ;
DR   A9VRT5, NAMA_BACWK ;  Q97E86, NAMA_CLOAB ;  Q5KXG9, NAMA_GEOKA ;
DR   C5D427, NAMA_GEOSW ;  A4IQK7, NAMA_GEOTN ;  Q928C2, NAMA_LISIN ;
DR   C1KYN8, NAMA_LISMC ;  Q71WV6, NAMA_LISMF ;  B8DBP0, NAMA_LISMH ;
DR   Q8Y4H1, NAMA_LISMO ;  A0ALF5, NAMA_LISW6 ;  Q02899, OYE1_SACPS ;
DR   Q03558, OYE2_YEAST ;  P41816, OYE3_YEAST ;  Q09670, OYEA_SCHPO ;
DR   Q09671, OYEB_SCHPO ;  O94467, OYEC_SCHPO ;
//
ID   1.6.99.2
DE   Transferred entry: 1.6.5.2.
//
ID   1.6.99.3
DE   NADH dehydrogenase.
AN   Beta-NADH dehydrogenase dinucleotide.
AN   Cytochrome c reductase.
AN   Diaphorase.
AN   Dihydrocodehydrogenase I dehydrogenase.
AN   Dihydronicotinamide adenine dinucleotide dehydrogenase.
AN   Diphosphopyrinase.
AN   DPNH diaphorase.
AN   NADH diaphorase.
AN   NADH hydrogenase.
AN   NADH oxidoreductase.
AN   NADH-menadione oxidoreductase.
AN   NADH:cytochrome c oxidoreductase.
AN   Reduced diphosphopyridine nucleotide diaphorase.
AN   Type 1 dehydrogenase.
AN   Type I dehydrogenase.
CA   NADH + acceptor = NAD(+) + reduced acceptor.
CF   Flavoprotein; Iron-sulfur.
CC   -!- After preparations have been subjected to certain treatments
CC       cytochrome c may act as acceptor.
CC   -!- Under normal conditions, two protons are extruded from the cytoplasm
CC       or the intramitochondrial or stromal compartment.
CC   -!- Present in a mitochondrial complex as EC 1.6.5.3.
CC   -!- Formerly EC 1.6.2.1.
PR   PROSITE; PDOC00496;
DR   P42974, DHNA_BACSU ;  P26829, DHNA_BACYN ;  P00393, DHNA_ECOLI ;
DR   P44856, DHNA_HAEIN ;  P37061, NAOX_ENTFA ;  A2RIB7, NAOX_LACLM ;
DR   Q58065, NAOX_METJA ;  Q49408, NAOX_MYCGE ;  P75389, NAOX_MYCPN ;
DR   Q5XC60, NAOX_STRP6 ;  Q42599, NDS8A_ARATH;  Q9FX83, NDS8B_ARATH;
DR   Q37373, NDUS1_ACACA;  Q9FGI6, NDUS1_ARATH;  P15690, NDUS1_BOVIN;
DR   Q2LCP5, NDUS1_DICCI;  Q34312, NDUS1_DICDI;  Q94511, NDUS1_DROME;
DR   Q0MQG1, NDUS1_GORGO;  P28331, NDUS1_HUMAN;  Q4R6K9, NDUS1_MACFA;
DR   P86203, NDUS1_MESAU;  Q91VD9, NDUS1_MOUSE;  P24918, NDUS1_NEUCR;
DR   Q0MQG2, NDUS1_PANTR;  P0CB67, NDUS1_PONAB;  P0CB68, NDUS1_PONPY;
DR   Q66HF1, NDUS1_RAT  ;  O21241, NDUS1_RECAM;  Q43644, NDUS1_SOLTU;
DR   Q37384, NDUS2_ACACA;  P93306, NDUS2_ARATH;  P17694, NDUS2_BOVIN;
DR   Q93873, NDUS2_CAEEL;  Q9TAJ7, NDUS2_CAFRO;  Q2LCR5, NDUS2_DICCI;
DR   Q23883, NDUS2_DICDI;  Q0MQG4, NDUS2_GORGO;  O75306, NDUS2_HUMAN;
DR   P86250, NDUS2_MESAU;  Q91WD5, NDUS2_MOUSE;  Q9TC96, NDUS2_NEPOL;
DR   P22142, NDUS2_NEUCR;  Q36450, NDUS2_NICSY;  Q5DUX5, NDUS2_NYCOV;
DR   Q0MQG5, NDUS2_PANTR;  P15689, NDUS2_PARTE;  Q0MQG3, NDUS2_PONPY;
DR   Q37619, NDUS2_PROWI;  Q37720, NDUS2_PYLLI;  Q641Y2, NDUS2_RAT  ;
DR   O21270, NDUS2_RECAM;  P80264, NDUS2_SOLTU;  Q37383, NDUS3_ACACA;
DR   Q95748, NDUS3_ARATH;  Q33994, NDUS3_BETTR;  Q37787, NDUS3_BETVU;
DR   P23709, NDUS3_BOVIN;  Q00673, NDUS3_CANMA;  Q2LCR4, NDUS3_DICCI;
DR   P22237, NDUS3_DICDI;  Q0MQG7, NDUS3_GORGO;  O75489, NDUS3_HUMAN;
DR   P34944, NDUS3_MARPO;  P86217, NDUS3_MESAU;  Q9DCT2, NDUS3_MOUSE;
DR   P23710, NDUS3_NEUCR;  Q35322, NDUS3_ORYSJ;  Q0MQG8, NDUS3_PANTR;
DR   P15601, NDUS3_PARPR;  P15600, NDUS3_PARTE;  Q34011, NDUS3_PATWE;
DR   Q0MQG6, NDUS3_PONPY;  Q37622, NDUS3_PROWI;  O21271, NDUS3_RECAM;
DR   P80261, NDUS3_SOLTU;  Q42577, NDUS7_ARATH;  P42026, NDUS7_BOVIN;
DR   P42027, NDUS7_BRAOL;  A8XFG2, NDUS7_CAEBR;  Q94360, NDUS7_CAEEL;
DR   Q0MQH9, NDUS7_GORGO;  O75251, NDUS7_HUMAN;  Q9DC70, NDUS7_MOUSE;
DR   O47950, NDUS7_NEUCR;  Q0MQI0, NDUS7_PANTR;  P0CB83, NDUS7_PONAB;
DR   P0CB84, NDUS7_PONPY;  Q43844, NDUS7_SOLTU;  Q26783, NDUS7_TRYBB;
DR   P42028, NDUS8_BOVIN;  Q22619, NDUS8_CAEEL;  Q0MQI2, NDUS8_GORGO;
DR   O00217, NDUS8_HUMAN;  Q60HE3, NDUS8_MACFA;  Q8K3J1, NDUS8_MOUSE;
DR   Q12644, NDUS8_NEUCR;  Q0MQI3, NDUS8_PANTR;  P0CB97, NDUS8_PONAB;
DR   P0CB98, NDUS8_PONPY;  P80269, NDUS8_SOLTU;  O24143, NDUS8_TOBAC;
DR   Q9FNN5, NDUV1_ARATH;  Q92406, NDUV1_ASPNG;  P25708, NDUV1_BOVIN;
DR   Q54I90, NDUV1_DICDI;  Q0MQI5, NDUV1_GORGO;  P49821, NDUV1_HUMAN;
DR   Q8HXQ9, NDUV1_MACFA;  Q91YT0, NDUV1_MOUSE;  P24917, NDUV1_NEUCR;
DR   Q0MQI6, NDUV1_PANTR;  Q0MQI4, NDUV1_PONPY;  O94500, NDUV1_SCHPO;
DR   O22769, NDUV2_ARATH;  P04394, NDUV2_BOVIN;  Q20719, NDUV2_CAEEL;
DR   P49820, NDUV2_CANFA;  Q54F10, NDUV2_DICDI;  Q0MQI8, NDUV2_GORGO;
DR   P19404, NDUV2_HUMAN;  Q9D6J6, NDUV2_MOUSE;  P40915, NDUV2_NEUCR;
DR   Q0MQI9, NDUV2_PANTR;  Q0MQI7, NDUV2_PONPY;  P19234, NDUV2_RAT  ;
DR   Q60049, NOX_THET8  ;  P25710, NUJM_NEUCR ;  P80268, NUO2_SOLTU ;
DR   P80263, NUO3_SOLTU ;  P80262, NUO5_SOLTU ;  P80729, NUO6_SOLTU ;
DR   P80730, NUO7_SOLTU ;  P80731, NUO8_SOLTU ;  P42116, NURM_NEUCR ;
DR   Q02854, NUXM_NEUCR ;  P19968, NUZM_NEUCR ;
//
ID   1.6.99.4
DE   Transferred entry: 1.18.1.2.
//
ID   1.6.99.5
DE   NADH dehydrogenase (quinone).
CA   NADH + acceptor = NAD(+) + reduced acceptor.
CC   -!- Menaquinone or other quinones can act as acceptor.
CC   -!- Inhibited by AMP and 2,4-dinitrophenol but not by dicoumarol or folic
CC       acid derivatives.
DR   P39755, NDHF_BACSU ;  P29922, NQO10_PARDE;  Q56225, NQO10_THET8;
DR   P29923, NQO11_PARDE;  Q56226, NQO11_THET8;  P29924, NQO12_PARDE;
DR   Q56227, NQO12_THET8;  P29925, NQO13_PARDE;  Q56228, NQO13_THET8;
DR   P29926, NQO14_PARDE;  Q56229, NQO14_THET8;  Q5SKZ7, NQO15_THET8;
DR   P29913, NQO1_PARDE ;  Q56222, NQO1_THET8 ;  P29914, NQO2_PARDE ;
DR   Q56221, NQO2_THET8 ;  P29915, NQO3_PARDE ;  Q56223, NQO3_THET8 ;
DR   P29916, NQO4_PARDE ;  Q56220, NQO4_THET8 ;  P29917, NQO5_PARDE ;
DR   Q56219, NQO5_THET8 ;  P29918, NQO6_PARDE ;  Q56218, NQO6_THET8 ;
DR   P29919, NQO7_PARDE ;  Q56217, NQO7_THET8 ;  P29920, NQO8_PARDE ;
DR   Q4QSC6, NQO8_RHOMR ;  Q60019, NQO8_THET8 ;  P29921, NQO9_PARDE ;
DR   Q4QSC5, NQO9_RHOMR ;  Q56224, NQO9_THET8 ;  B5E972, NUBCD_GEOBB;
DR   Q39ZC4, NUBCD_GEOMG;  Q746S4, NUBCD_GEOSL;  A5GCZ4, NUBCD_GEOUR;
DR   Q3A825, NUBCD_PELCD;  A0LJM5, NUBCD_SYNFM;  O66826, NUCD1_AQUAE;
DR   O67335, NUCD2_AQUAE;  B3QUX5, NUOA1_CHLT3;  B5E973, NUOA1_GEOBB;
DR   Q39ZC5, NUOA1_GEOMG;  Q74GA8, NUOA1_GEOSL;  A5GCZ5, NUOA1_GEOUR;
DR   A6V4E9, NUOA1_PSEA7;  Q02NC9, NUOA1_PSEAB;  Q9I2L4, NUOA1_PSEAE;
DR   O68852, NUOA1_RHIME;  B3QY48, NUOA2_CHLT3;  B5EFG3, NUOA2_GEOBB;
DR   Q39QA7, NUOA2_GEOMG;  Q746S3, NUOA2_GEOSL;  A5G9B9, NUOA2_GEOUR;
DR   A6V6S8, NUOA2_PSEA7;  Q02L30, NUOA2_PSEAB;  Q9I0K1, NUOA2_PSEAE;
DR   P56895, NUOA2_RHIME;  A1TLL6, NUOA_ACIAC ;  Q6FE71, NUOA_ACIAD ;
DR   B2HU41, NUOA_ACIBC ;  B0VU56, NUOA_ACIBS ;  A3M2P8, NUOA_ACIBT ;
DR   B0V7U8, NUOA_ACIBY ;  A5FXK0, NUOA_ACICJ ;  B5EN71, NUOA_ACIF5 ;
DR   A1W4M2, NUOA_ACISJ ;  A0KJ67, NUOA_AERHH ;  A4SLP4, NUOA_AERS4 ;
DR   Q2IL11, NUOA_ANADE ;  A7H9V2, NUOA_ANADF ;  B4UIA6, NUOA_ANASK ;
DR   Q81K00, NUOA_BACAN ;  Q72XF3, NUOA_BACC1 ;  A7GV51, NUOA_BACCN ;
DR   Q814W6, NUOA_BACCR ;  Q630U8, NUOA_BACCZ ;  Q5LH48, NUOA_BACFN ;
DR   Q64Y06, NUOA_BACFR ;  Q6HAY5, NUOA_BACHK ;  Q8A0F4, NUOA_BACTN ;
DR   A6L171, NUOA_BACV8 ;  A9VS98, NUOA_BACWK ;  Q1LT89, NUOA_BAUCH ;
DR   Q7VRV2, NUOA_BLOFL ;  Q492H6, NUOA_BLOPB ;  P57252, NUOA_BUCAI ;
DR   Q8K9Y7, NUOA_BUCAP ;  Q89AU6, NUOA_BUCBP ;  B1YTQ7, NUOA_BURA4 ;
DR   Q1BV13, NUOA_BURCA ;  B1JVP1, NUOA_BURCC ;  A0K923, NUOA_BURCH ;
DR   B4E5M2, NUOA_BURCJ ;  Q0BDD0, NUOA_BURCM ;  A9AJP4, NUOA_BURM1 ;
DR   A3MIA1, NUOA_BURM7 ;  A2S459, NUOA_BURM9 ;  Q62IN5, NUOA_BURMA ;
DR   A1V2L6, NUOA_BURMS ;  A3NTA6, NUOA_BURP0 ;  Q3JUA9, NUOA_BURP1 ;
DR   A3N7L7, NUOA_BURP6 ;  B2JDM8, NUOA_BURP8 ;  B2T2E7, NUOA_BURPP ;
DR   Q63VN3, NUOA_BURPS ;  Q39EE5, NUOA_BURS3 ;  Q2SZN5, NUOA_BURTA ;
DR   A4JGD0, NUOA_BURVG ;  Q142H3, NUOA_BURXL ;  Q3AC77, NUOA_CARHZ ;
DR   A9WEE0, NUOA_CHLAA ;  Q3ASW8, NUOA_CHLCH ;  B3EI93, NUOA_CHLL2 ;
DR   B3QP58, NUOA_CHLP8 ;  B3EKA1, NUOA_CHLPB ;  A1BF32, NUOA_CHLPD ;
DR   Q8KEC3, NUOA_CHLTE ;  Q1QST2, NUOA_CHRSD ;  A8ADV1, NUOA_CITK8 ;
DR   A6LXQ5, NUOA_CLOB8 ;  A9KBK4, NUOA_COXBN ;  A9N8X3, NUOA_COXBR ;
DR   Q83BQ5, NUOA_COXBU ;  Q473U3, NUOA_CUPPJ ;  Q11VB2, NUOA_CYTH3 ;
DR   A9BNB4, NUOA_DELAS ;  Q24UB5, NUOA_DESHY ;  A4J660, NUOA_DESRM ;
DR   A7ZPA2, NUOA_ECO24 ;  P0AFC5, NUOA_ECO57 ;  B1X900, NUOA_ECODH ;
DR   A8A2F7, NUOA_ECOHS ;  A1ADD6, NUOA_ECOK1 ;  Q0TFF8, NUOA_ECOL5 ;
DR   P0AFC4, NUOA_ECOL6 ;  B1IXQ4, NUOA_ECOLC ;  P0AFC3, NUOA_ECOLI ;
DR   B1LLP1, NUOA_ECOSM ;  Q1R9C9, NUOA_ECOUT ;  A4WCR7, NUOA_ENT38 ;
DR   A7MH22, NUOA_ENTS8 ;  Q6D2R7, NUOA_ERWCT ;  B2VIV3, NUOA_ERWT9 ;
DR   A6H1R4, NUOA_FLAPJ ;  Q5KUJ5, NUOA_GEOKA ;  B3E9W9, NUOA_GEOLS ;
DR   A4ITI7, NUOA_GEOTN ;  A9HNA0, NUOA_GLUDA ;  B0TH77, NUOA_HELMI ;
DR   A9B477, NUOA_HERA2 ;  A6TBX4, NUOA_KLEP7 ;  B1Y827, NUOA_LEPCP ;
DR   Q608X7, NUOA_METCA ;  Q2RJU7, NUOA_MOOTA ;  P65564, NUOA_MYCBO ;
DR   P65563, NUOA_MYCTU ;  Q1D8S2, NUOA_MYXXD ;  Q2GDY1, NUOA_NEOSM ;
DR   Q82TU3, NUOA_NITEU ;  Q2YAA5, NUOA_NITMU ;  Q3JC15, NUOA_NITOC ;
DR   O85273, NUOA_PECCC ;  Q3A826, NUOA_PELCD ;  Q3B4W3, NUOA_PELLD ;
DR   B4SBZ3, NUOA_PELPB ;  Q4FM91, NUOA_PELUB ;  Q7N2I7, NUOA_PHOLL ;
DR   A1VM60, NUOA_POLNA ;  B1XUJ8, NUOA_POLNS ;  A4SXQ3, NUOA_POLSQ ;
DR   B4S751, NUOA_PROA2 ;  B4EZD0, NUOA_PROMH ;  A4SF48, NUOA_PROVI ;
DR   Q48H54, NUOA_PSE14 ;  Q1I800, NUOA_PSEE4 ;  A4XV02, NUOA_PSEMY ;
DR   A5W192, NUOA_PSEP1 ;  Q3KA63, NUOA_PSEPF ;  B0KMX8, NUOA_PSEPG ;
DR   Q88FH7, NUOA_PSEPK ;  B1J6N4, NUOA_PSEPW ;  Q87ZQ9, NUOA_PSESM ;
DR   Q4ZRJ3, NUOA_PSEU2 ;  Q4FU64, NUOA_PSYA2 ;  Q1QD97, NUOA_PSYCK ;
DR   A5WG48, NUOA_PSYWF ;  B2U7R1, NUOA_RALPJ ;  Q8XXQ1, NUOA_RALSO ;
DR   O84969, NUOA_RHOCA ;  Q21YC7, NUOA_RHOFD ;  Q2J0F3, NUOA_RHOP2 ;
DR   Q07QX5, NUOA_RHOP5 ;  Q6N1Y8, NUOA_RHOPA ;  Q20Z39, NUOA_RHOPB ;
DR   Q13BH5, NUOA_RHOPS ;  B3Q6T5, NUOA_RHOPT ;  Q1RJI5, NUOA_RICBR ;
DR   Q92ID5, NUOA_RICCN ;  Q4UM05, NUOA_RICFE ;  Q9ZDH1, NUOA_RICPR ;
DR   Q68X16, NUOA_RICTY ;  A7NL04, NUOA_ROSCS ;  A5UXK0, NUOA_ROSS1 ;
DR   B5EZK9, NUOA_SALA4 ;  A9MJ97, NUOA_SALAR ;  Q57M28, NUOA_SALCH ;
DR   B5FPG9, NUOA_SALDC ;  B5R309, NUOA_SALEP ;  B5RCF3, NUOA_SALG2 ;
DR   B4TBJ4, NUOA_SALHS ;  B4SYZ9, NUOA_SALNS ;  Q5PN55, NUOA_SALPA ;
DR   A9N4C4, NUOA_SALPB ;  B5BCL8, NUOA_SALPK ;  B4TPL0, NUOA_SALSV ;
DR   Q8XFY2, NUOA_SALTI ;  Q7CQ49, NUOA_SALTY ;  A8GH16, NUOA_SERP5 ;
DR   Q8EI29, NUOA_SHEON ;  B2TW69, NUOA_SHIB3 ;  Q31YH3, NUOA_SHIBS ;
DR   Q32DQ1, NUOA_SHIDS ;  Q0T2J9, NUOA_SHIF8 ;  P0AFC6, NUOA_SHIFL ;
DR   Q3YZS2, NUOA_SHISS ;  Q2NSJ9, NUOA_SODGM ;  Q02CU2, NUOA_SOLUE ;
DR   A0LJM6, NUOA_SYNFM ;  A1WLP4, NUOA_VEREI ;  A1JLG0, NUOA_YERE8 ;
DR   A7FGQ5, NUOA_YERP3 ;  Q1C6A9, NUOA_YERPA ;  B2K821, NUOA_YERPB ;
DR   Q0WDX2, NUOA_YERPE ;  A9R6M0, NUOA_YERPG ;  Q1CHQ1, NUOA_YERPN ;
DR   A4TM36, NUOA_YERPP ;  Q669A0, NUOA_YERPS ;  B1JGL3, NUOA_YERPY ;
DR   Q1IPE7, NUOB1_ACIBL;  A5FX09, NUOB1_ACICJ;  B5EM21, NUOB1_ACIF5;
DR   Q2IL12, NUOB1_ANADE;  A7H9V0, NUOB1_ANADF;  B4UIA4, NUOB1_ANASK;
DR   A1K5A9, NUOB1_AZOSB;  A3MIA2, NUOB1_BURM7;  A2S458, NUOB1_BURM9;
DR   Q62IN6, NUOB1_BURMA;  A1V2L7, NUOB1_BURMS;  A3NTA7, NUOB1_BURP0;
DR   Q3JUA8, NUOB1_BURP1;  A3N7L8, NUOB1_BURP6;  Q63VN2, NUOB1_BURPS;
DR   A9WED9, NUOB1_CHLAA;  B8G705, NUOB1_CHLAD;  B9LGT9, NUOB1_CHLSY;
DR   B3QUS2, NUOB1_CHLT3;  Q7NZI0, NUOB1_CHRVO;  Q11XR8, NUOB1_CYTH3;
DR   A9HN98, NUOB1_GLUDA;  A9B4Z5, NUOB1_HERA2;  Q2YAA4, NUOB1_NITMU;
DR   Q3JC16, NUOB1_NITOC;  B1ZRT2, NUOB1_OPITP;  B3PVZ8, NUOB1_RHIE6;
DR   Q2K9T4, NUOB1_RHIEC;  O68853, NUOB1_RHIME;  Q07QX4, NUOB1_RHOP5;
DR   Q6N5M3, NUOB1_RHOPA;  Q215I4, NUOB1_RHOPB;  Q13BH4, NUOB1_RHOPS;
DR   B3Q7N5, NUOB1_RHOPT;  A3PIW9, NUOB1_RHOS1;  Q3J3G0, NUOB1_RHOS4;
DR   A4WT69, NUOB1_RHOS5;  B9KQW1, NUOB1_RHOSK;  A7NIW1, NUOB1_ROSCS;
DR   A5UXK1, NUOB1_ROSS1;  A8M069, NUOB1_SALAI;  A4X1X5, NUOB1_SALTO;
DR   Q020B6, NUOB1_SOLUE;  A9GUX6, NUOB1_SORC5;  Q82DY0, NUOB1_STRAW;
DR   Q9XAQ5, NUOB1_STRCO;  B1W518, NUOB1_STRGG;  Q67P21, NUOB1_SYMTH;
DR   B5YKI3, NUOB1_THEYD;  Q1IL91, NUOB2_ACIBL;  A5FXJ9, NUOB2_ACICJ;
DR   B5EN70, NUOB2_ACIF5;  Q2IL09, NUOB2_ANADE;  A7H9V3, NUOB2_ANADF;
DR   B4UIA7, NUOB2_ANASK;  A1K3P1, NUOB2_AZOSB;  A3MFR5, NUOB2_BURM7;
DR   A2RYJ4, NUOB2_BURM9;  Q62DE1, NUOB2_BURMA;  A1UWB1, NUOB2_BURMS;
DR   A3NZQ8, NUOB2_BURP0;  Q3JNA0, NUOB2_BURP1;  A3NE04, NUOB2_BURP6;
DR   Q63QG0, NUOB2_BURPS;  A9WFB2, NUOB2_CHLAA;  B8GA16, NUOB2_CHLAD;
DR   B9LAU1, NUOB2_CHLSY;  B3QY47, NUOB2_CHLT3;  Q7NUE5, NUOB2_CHRVO;
DR   Q11VB3, NUOB2_CYTH3;  A9HRU3, NUOB2_GLUDA;  A9B478, NUOB2_HERA2;
DR   Q2YA26, NUOB2_NITMU;  Q3J829, NUOB2_NITOC;  B1ZUJ0, NUOB2_OPITP;
DR   B3PY57, NUOB2_RHIE6;  Q2K755, NUOB2_RHIEC;  P56897, NUOB2_RHIME;
DR   Q07NM6, NUOB2_RHOP5;  Q6N1Y9, NUOB2_RHOPA;  Q20Z40, NUOB2_RHOPB;
DR   Q135X5, NUOB2_RHOPS;  B3Q6T4, NUOB2_RHOPT;  A3PKI1, NUOB2_RHOS1;
DR   Q3J1Q8, NUOB2_RHOS4;  A4WU33, NUOB2_RHOS5;  B9KJI0, NUOB2_RHOSK;
DR   A7NL05, NUOB2_ROSCS;  A5UZH9, NUOB2_ROSS1;  A8M621, NUOB2_SALAI;
DR   A4XC37, NUOB2_SALTO;  Q01VP7, NUOB2_SOLUE;  A9G9S9, NUOB2_SORC5;
DR   Q82DT6, NUOB2_STRAW;  Q9F2W1, NUOB2_STRCO;  B1W4V9, NUOB2_STRGG;
DR   Q67KN6, NUOB2_SYMTH;  B5YL35, NUOB2_THEYD;  Q2K3U4, NUOB3_RHIEC;
DR   A1TLL7, NUOB_ACIAC ;  Q6FE70, NUOB_ACIAD ;  B7GZC0, NUOB_ACIB3 ;
DR   B7I740, NUOB_ACIB5 ;  B2HU42, NUOB_ACIBC ;  B0VU55, NUOB_ACIBS ;
DR   A3M2P9, NUOB_ACIBT ;  B0V7U7, NUOB_ACIBY ;  A0LRI2, NUOB_ACIC1 ;
DR   B9MEL5, NUOB_ACIET ;  B7J6H2, NUOB_ACIF2 ;  A1W4M3, NUOB_ACISJ ;
DR   A0KJ66, NUOB_AERHH ;  A4SLP3, NUOB_AERS4 ;  B9JD43, NUOB_AGRRK ;
DR   A9CJB2, NUOB_AGRT5 ;  B9JVE6, NUOB_AGRVS ;  B2UPT6, NUOB_AKKM8 ;
DR   Q0A776, NUOB_ALHEH ;  B3ET80, NUOB_AMOA5 ;  B8JH22, NUOB_ANAD2 ;
DR   B9KI91, NUOB_ANAMF ;  Q5PB32, NUOB_ANAMM ;  Q2GKI6, NUOB_ANAPZ ;
DR   B7GMF0, NUOB_ANOFW ;  O67334, NUOB_AQUAE ;  A8ERL5, NUOB_ARCB4 ;
DR   Q5P1E9, NUOB_AROAE ;  A8I3Y7, NUOB_AZOC5 ;  B6YR59, NUOB_AZOPC ;
DR   C1DL15, NUOB_AZOVD ;  C3P1E8, NUOB_BACAA ;  C3LFH3, NUOB_BACAC ;
DR   A0RL90, NUOB_BACAH ;  Q81K01, NUOB_BACAN ;  B7JGM4, NUOB_BACC0 ;
DR   Q72XF4, NUOB_BACC1 ;  B7IQV2, NUOB_BACC2 ;  C1F0M2, NUOB_BACC3 ;
DR   B7HFJ5, NUOB_BACC4 ;  B7HY57, NUOB_BACC7 ;  A7GV50, NUOB_BACCN ;
DR   B9IRT1, NUOB_BACCQ ;  Q814W7, NUOB_BACCR ;  Q630U9, NUOB_BACCZ ;
DR   Q5LH49, NUOB_BACFN ;  Q64Y07, NUOB_BACFR ;  Q6HAY6, NUOB_BACHK ;
DR   Q8A0F5, NUOB_BACTN ;  A6L170, NUOB_BACV8 ;  A9VS97, NUOB_BACWK ;
DR   A1USW8, NUOB_BARBK ;  Q6G389, NUOB_BARHE ;  Q6FZZ0, NUOB_BARQU ;
DR   A9IUQ3, NUOB_BART1 ;  Q1LT90, NUOB_BAUCH ;  Q6MIR4, NUOB_BDEBA ;
DR   B2IHW6, NUOB_BEII9 ;  C5C0S6, NUOB_BEUC1 ;  Q7VRV3, NUOB_BLOFL ;
DR   Q492H7, NUOB_BLOPB ;  Q2KV17, NUOB_BORA1 ;  Q7WCU0, NUOB_BORBR ;
DR   Q7W5A8, NUOB_BORPA ;  A9II02, NUOB_BORPD ;  Q7VZQ4, NUOB_BORPE ;
DR   Q89KI7, NUOB_BRAJA ;  A5EK99, NUOB_BRASB ;  A4YVL1, NUOB_BRASO ;
DR   C0Z772, NUOB_BREBN ;  B2S544, NUOB_BRUA1 ;  Q2YNC8, NUOB_BRUA2 ;
DR   Q57DV0, NUOB_BRUAB ;  A9MAI0, NUOB_BRUC2 ;  C0RIE0, NUOB_BRUMB ;
DR   Q8YGK1, NUOB_BRUME ;  A5VPY4, NUOB_BRUO2 ;  B0CLD0, NUOB_BRUSI ;
DR   Q8G1B6, NUOB_BRUSU ;  B8D8V6, NUOB_BUCA5 ;  P57253, NUOB_BUCAI ;
DR   Q8K9Y6, NUOB_BUCAP ;  B8D760, NUOB_BUCAT ;  Q89AU5, NUOB_BUCBP ;
DR   Q057X4, NUOB_BUCCC ;  B1YTQ6, NUOB_BURA4 ;  Q1BV14, NUOB_BURCA ;
DR   B1JVP0, NUOB_BURCC ;  A0K922, NUOB_BURCH ;  B4E5M1, NUOB_BURCJ ;
DR   Q0BDD1, NUOB_BURCM ;  A9AFY8, NUOB_BURM1 ;  B2JDM7, NUOB_BURP8 ;
DR   B2T2E8, NUOB_BURPP ;  Q39EE6, NUOB_BURS3 ;  Q2SZN4, NUOB_BURTA ;
DR   A4JGC9, NUOB_BURVG ;  Q142H2, NUOB_BURXL ;  A7ZBE5, NUOB_CAMC1 ;
DR   A7GW69, NUOB_CAMC5 ;  A0RMD0, NUOB_CAMFF ;  A7HZU9, NUOB_CAMHC ;
DR   A8FNN6, NUOB_CAMJ8 ;  A7H5T0, NUOB_CAMJD ;  Q0P850, NUOB_CAMJE ;
DR   A1W1H7, NUOB_CAMJJ ;  Q5HSL3, NUOB_CAMJR ;  Q3AC78, NUOB_CARHZ ;
DR   B8GWV5, NUOB_CAUCN ;  Q9A6X1, NUOB_CAUCR ;  B0SZ51, NUOB_CAUSK ;
DR   Q3ASW7, NUOB_CHLCH ;  B3EI94, NUOB_CHLL2 ;  B3QP57, NUOB_CHLP8 ;
DR   B3EKA0, NUOB_CHLPB ;  A1BF33, NUOB_CHLPD ;  Q8KEC2, NUOB_CHLTE ;
DR   Q1QST3, NUOB_CHRSD ;  A8ADV2, NUOB_CITK8 ;  A6LXQ4, NUOB_CLOB8 ;
DR   B6J695, NUOB_COXB1 ;  B6IZ46, NUOB_COXB2 ;  A9KBK5, NUOB_COXBN ;
DR   A9N8X2, NUOB_COXBR ;  Q83BQ6, NUOB_COXBU ;  Q0KCS9, NUOB_CUPNH ;
DR   Q473U2, NUOB_CUPPJ ;  B3R3W8, NUOB_CUPTR ;  Q47HH5, NUOB_DECAR ;
DR   Q3Z800, NUOB_DEHE1 ;  A5FQY4, NUOB_DEHSB ;  Q3ZXS0, NUOB_DEHSC ;
DR   C1D0H2, NUOB_DEIDV ;  Q1IZX2, NUOB_DEIGD ;  Q9RU87, NUOB_DEIRA ;
DR   A9BNB3, NUOB_DELAS ;  B8J1D6, NUOB_DESDA ;  B8FRK6, NUOB_DESHD ;
DR   Q24UB6, NUOB_DESHY ;  A4J659, NUOB_DESRM ;  B8DS03, NUOB_DESVM ;
DR   A8LIT6, NUOB_DINSH ;  A7ZPA1, NUOB_ECO24 ;  B7UFU5, NUOB_ECO27 ;
DR   B7MG51, NUOB_ECO45 ;  B7LBP8, NUOB_ECO55 ;  P0AFC9, NUOB_ECO57 ;
DR   B5YXS7, NUOB_ECO5E ;  B7NNW6, NUOB_ECO7I ;  B7MXW6, NUOB_ECO81 ;
DR   B7M5W6, NUOB_ECO8A ;  C4ZUD0, NUOB_ECOBW ;  B1X8Z9, NUOB_ECODH ;
DR   A8A2F6, NUOB_ECOHS ;  A1ADD5, NUOB_ECOK1 ;  Q0TFF9, NUOB_ECOL5 ;
DR   P0AFC8, NUOB_ECOL6 ;  B1IXQ5, NUOB_ECOLC ;  P0AFC7, NUOB_ECOLI ;
DR   B7N5P9, NUOB_ECOLU ;  B6I7N7, NUOB_ECOSE ;  B1LLP0, NUOB_ECOSM ;
DR   Q1R9D0, NUOB_ECOUT ;  C5B8I5, NUOB_EDWI9 ;  Q2GG48, NUOB_EHRCR ;
DR   Q5FHF7, NUOB_EHRRG ;  Q5HBM2, NUOB_EHRRW ;  A4WCR6, NUOB_ENT38 ;
DR   A7MH23, NUOB_ENTS8 ;  Q6D2R8, NUOB_ERWCT ;  B2VIV4, NUOB_ERWT9 ;
DR   Q2NA61, NUOB_ERYLH ;  B7LM45, NUOB_ESCF3 ;  A5FKI9, NUOB_FLAJ1 ;
DR   A6H1R3, NUOB_FLAPJ ;  Q0RRW7, NUOB_FRAAA ;  B0TWP5, NUOB_FRAP2 ;
DR   Q2JFL9, NUOB_FRASC ;  A8LCA0, NUOB_FRASN ;  Q14K37, NUOB_FRAT1 ;
DR   A7NEK9, NUOB_FRATF ;  Q2A1F1, NUOB_FRATH ;  B2SEV0, NUOB_FRATM ;
DR   A0Q8H1, NUOB_FRATN ;  Q0BK52, NUOB_FRATO ;  Q5NIN4, NUOB_FRATT ;
DR   A4IVZ3, NUOB_FRATW ;  B5EFG2, NUOB_GEOBB ;  Q5KUJ6, NUOB_GEOKA ;
DR   B3E9W8, NUOB_GEOLS ;  Q39QA8, NUOB_GEOMG ;  B9LZL8, NUOB_GEOSF ;
DR   Q74GA7, NUOB_GEOSL ;  C6E8N4, NUOB_GEOSM ;  C5D987, NUOB_GEOSW ;
DR   A4ITI6, NUOB_GEOTN ;  A5G9B8, NUOB_GEOUR ;  Q0BSK3, NUOB_GRABC ;
DR   A1WXW6, NUOB_HALHL ;  Q17Z53, NUOB_HELAH ;  Q7VFS3, NUOB_HELHP ;
DR   B0TH78, NUOB_HELMI ;  B6JNA1, NUOB_HELP2 ;  B5Z8Q6, NUOB_HELPG ;
DR   Q1CS00, NUOB_HELPH ;  Q9ZJW6, NUOB_HELPJ ;  B2UV25, NUOB_HELPS ;
DR   O25851, NUOB_HELPY ;  A4G643, NUOB_HERAR ;  B4U8H3, NUOB_HYDS0 ;
DR   Q0C1E6, NUOB_HYPNA ;  A6SY06, NUOB_JANMA ;  Q28T75, NUOB_JANSC ;
DR   B5XNV5, NUOB_KLEP3 ;  A6TBX3, NUOB_KLEP7 ;  C1DCA4, NUOB_LARHH ;
DR   Q5X1A8, NUOB_LEGPA ;  A5IHW2, NUOB_LEGPC ;  Q5ZRT9, NUOB_LEGPH ;
DR   Q5WT21, NUOB_LEGPL ;  B0SFT5, NUOB_LEPBA ;  Q04V71, NUOB_LEPBJ ;
DR   Q04YA5, NUOB_LEPBL ;  B0SP83, NUOB_LEPBP ;  B1Y828, NUOB_LEPCP ;
DR   Q72NT7, NUOB_LEPIC ;  Q8F7Q0, NUOB_LEPIN ;  Q2W3I5, NUOB_MAGSA ;
DR   A0LDS6, NUOB_MAGSM ;  Q0APY9, NUOB_MARMM ;  Q11JK5, NUOB_MESSB ;
DR   B7KQ65, NUOB_METC4 ;  Q608X8, NUOB_METCA ;  A9W1N2, NUOB_METEP ;
DR   Q1GZL0, NUOB_METFK ;  B3DXN5, NUOB_METI4 ;  B8IUU7, NUOB_METNO ;
DR   B1ZA45, NUOB_METPB ;  A2SFM7, NUOB_METPP ;  B1LUN6, NUOB_METRJ ;
DR   B0ULK5, NUOB_METS4 ;  B8EIL8, NUOB_METSB ;  Q2RJU6, NUOB_MOOTA ;
DR   A0QJU8, NUOB_MYCA1 ;  B1MPG5, NUOB_MYCA9 ;  P65576, NUOB_MYCBO ;
DR   A1KNE2, NUOB_MYCBP ;  C1AGR3, NUOB_MYCBT ;  A4TDB9, NUOB_MYCGI ;
DR   B2HGE7, NUOB_MYCMM ;  Q73V14, NUOB_MYCPA ;  A0QU35, NUOB_MYCS2 ;
DR   A3PWS0, NUOB_MYCSJ ;  Q1BBP4, NUOB_MYCSS ;  A5U7G2, NUOB_MYCTA ;
DR   P65575, NUOB_MYCTU ;  A0PR39, NUOB_MYCUA ;  A1T6A5, NUOB_MYCVP ;
DR   Q1D8S3, NUOB_MYXXD ;  Q5F616, NUOB_NEIG1 ;  B4RPI3, NUOB_NEIG2 ;
DR   A1INN9, NUOB_NEIMA ;  Q9K1C2, NUOB_NEIMB ;  A1KRS3, NUOB_NEIMF ;
DR   Q2GDX9, NUOB_NEOSM ;  Q0AHJ9, NUOB_NITEC ;  Q82TU4, NUOB_NITEU ;
DR   Q1QL85, NUOB_NITHX ;  A6Q1P4, NUOB_NITSB ;  Q3SRE4, NUOB_NITWN ;
DR   Q5YWC8, NUOB_NOCFA ;  A1SE28, NUOB_NOCSJ ;  Q2G5Y4, NUOB_NOVAD ;
DR   A6X1N3, NUOB_OCHA4 ;  B6JGW0, NUOB_OLICO ;  A5CES0, NUOB_ORITB ;
DR   B3CSG9, NUOB_ORITI ;  A1B497, NUOB_PARDP ;  A7HY48, NUOB_PARL1 ;
DR   Q6MDR5, NUOB_PARUW ;  O85274, NUOB_PECCC ;  C6DA45, NUOB_PECCP ;
DR   Q3B4W2, NUOB_PELLD ;  B4SBZ2, NUOB_PELPB ;  A1ALP0, NUOB_PELPD ;
DR   Q4FM90, NUOB_PELUB ;  B4RCM8, NUOB_PHEZH ;  Q7N2I8, NUOB_PHOLL ;
DR   A1VM61, NUOB_POLNA ;  B1XUJ9, NUOB_POLNS ;  Q127X3, NUOB_POLSJ ;
DR   A4SXQ2, NUOB_POLSQ ;  B4S752, NUOB_PROA2 ;  Q6A6F9, NUOB_PROAC ;
DR   B4EZC9, NUOB_PROMH ;  A4SF47, NUOB_PROVI ;  Q48H53, NUOB_PSE14 ;
DR   A6V4E8, NUOB_PSEA7 ;  B7VAR4, NUOB_PSEA8 ;  Q02ND0, NUOB_PSEAB ;
DR   Q9I0K0, NUOB_PSEAE ;  Q1I7Z9, NUOB_PSEE4 ;  Q4K9T5, NUOB_PSEF5 ;
DR   C3JY82, NUOB_PSEFS ;  A4XV03, NUOB_PSEMY ;  A5W191, NUOB_PSEP1 ;
DR   Q3KA62, NUOB_PSEPF ;  B0KMX9, NUOB_PSEPG ;  Q88FH6, NUOB_PSEPK ;
DR   B1J6N3, NUOB_PSEPW ;  Q87ZQ8, NUOB_PSESM ;  Q4ZRJ2, NUOB_PSEU2 ;
DR   Q4FU63, NUOB_PSYA2 ;  Q1QD96, NUOB_PSYCK ;  A5WG47, NUOB_PSYWF ;
DR   Q1LPW2, NUOB_RALME ;  B2U7R0, NUOB_RALPJ ;  Q8XXQ2, NUOB_RALSO ;
DR   Q1MIL4, NUOB_RHIL3 ;  Q98KQ6, NUOB_RHILO ;  B5ZYL3, NUOB_RHILW ;
DR   O84970, NUOB_RHOCA ;  B6ISY0, NUOB_RHOCS ;  C0ZYJ9, NUOB_RHOE4 ;
DR   Q21YC6, NUOB_RHOFD ;  C1AYM4, NUOB_RHOOB ;  Q2J0F2, NUOB_RHOP2 ;
DR   Q2RU39, NUOB_RHORT ;  Q0S449, NUOB_RHOSR ;  C3PN71, NUOB_RICAE ;
DR   A8GN54, NUOB_RICAH ;  A8GX77, NUOB_RICB8 ;  Q1RJI6, NUOB_RICBR ;
DR   A8EZ83, NUOB_RICCK ;  Q92ID6, NUOB_RICCN ;  Q4UM06, NUOB_RICFE ;
DR   A8F1C7, NUOB_RICM5 ;  Q9ZDH2, NUOB_RICPR ;  C4K2P3, NUOB_RICPU ;
DR   B0BX73, NUOB_RICRO ;  A8GRR7, NUOB_RICRS ;  Q68X17, NUOB_RICTY ;
DR   Q163Q1, NUOB_ROSDO ;  Q1AVI4, NUOB_RUBXD ;  A1AVR3, NUOB_RUTMC ;
DR   A4FPU0, NUOB_SACEN ;  B5EZK8, NUOB_SALA4 ;  A9MJ98, NUOB_SALAR ;
DR   Q57M29, NUOB_SALCH ;  B5FPG8, NUOB_SALDC ;  B5R308, NUOB_SALEP ;
DR   B5RCF2, NUOB_SALG2 ;  B4TBJ3, NUOB_SALHS ;  B4SYZ8, NUOB_SALNS ;
DR   Q5PN54, NUOB_SALPA ;  A9N581, NUOB_SALPB ;  C0Q040, NUOB_SALPC ;
DR   B5BCL9, NUOB_SALPK ;  Q2S5J2, NUOB_SALRD ;  B4TPK9, NUOB_SALSV ;
DR   Q8XGN7, NUOB_SALTI ;  Q7CQ50, NUOB_SALTY ;  A8GH15, NUOB_SERP5 ;
DR   Q8EI30, NUOB_SHEON ;  B1KJU9, NUOB_SHEWM ;  B2TW68, NUOB_SHIB3 ;
DR   Q31YH4, NUOB_SHIBS ;  Q32DQ2, NUOB_SHIDS ;  Q0T2K0, NUOB_SHIF8 ;
DR   P0AFD0, NUOB_SHIFL ;  Q3YZS3, NUOB_SHISS ;  Q5LPR4, NUOB_SILPO ;
DR   Q1GIP1, NUOB_SILST ;  A6U7W4, NUOB_SINMW ;  Q2NSK0, NUOB_SODGM ;
DR   Q1GTJ8, NUOB_SPHAL ;  A5VAL8, NUOB_SPHWW ;  B4SQT5, NUOB_STRM5 ;
DR   B2FNX8, NUOB_STRMK ;  Q30PH9, NUOB_SULDN ;  A6QCG2, NUOB_SULNB ;
DR   B2V988, NUOB_SULSY ;  Q47LE5, NUOB_THEFY ;  B9L170, NUOB_THERP ;
DR   Q72GC9, NUOB_THET2 ;  Q31HF9, NUOB_THICR ;  Q3SEX7, NUOB_THIDA ;
DR   B8GNY6, NUOB_THISH ;  C4LB32, NUOB_TOLAT ;  C5CT19, NUOB_VARPS ;
DR   A1WLP3, NUOB_VEREI ;  A5CXF8, NUOB_VESOH ;  Q73G42, NUOB_WOLPM ;
DR   B3CM42, NUOB_WOLPP ;  Q7MA50, NUOB_WOLSU ;  Q5GT43, NUOB_WOLTR ;
DR   C0R4Y2, NUOB_WOLWR ;  Q8PJ41, NUOB_XANAC ;  Q3BRN0, NUOB_XANC5 ;
DR   Q4UWB7, NUOB_XANC8 ;  B0RR99, NUOB_XANCB ;  Q8P7T3, NUOB_XANCP ;
DR   Q2P0V6, NUOB_XANOM ;  B2SVL8, NUOB_XANOP ;  Q5GXT2, NUOB_XANOR ;
DR   A7IPA6, NUOB_XANP2 ;  B2I785, NUOB_XYLF2 ;  Q9PGJ4, NUOB_XYLFA ;
DR   B0U1W6, NUOB_XYLFM ;  Q87EQ4, NUOB_XYLFT ;  A1JLG4, NUOB_YERE8 ;
DR   A7FGQ6, NUOB_YERP3 ;  Q1C6B0, NUOB_YERPA ;  B2K820, NUOB_YERPB ;
DR   Q7CJ93, NUOB_YERPE ;  A9R6L9, NUOB_YERPG ;  Q1CHQ2, NUOB_YERPN ;
DR   A4TM35, NUOB_YERPP ;  Q669A1, NUOB_YERPS ;  B1JGL4, NUOB_YERPY ;
DR   B3PVZ9, NUOC1_RHIE6;  O68854, NUOC1_RHIME;  B3PY58, NUOC2_RHIE6;
DR   P56896, NUOC2_RHIME;  Q6FE69, NUOCD_ACIAD;  B7GZB9, NUOCD_ACIB3;
DR   B7I741, NUOCD_ACIB5;  B2HU43, NUOCD_ACIBC;  B0VU54, NUOCD_ACIBS;
DR   A3M2Q0, NUOCD_ACIBT;  B0V899, NUOCD_ACIBY;  A5FXJ8, NUOCD_ACICJ;
DR   A0KJ65, NUOCD_AERHH;  A4SLP2, NUOCD_AERS4;  A8ERL4, NUOCD_ARCB4;
DR   C1DL16, NUOCD_AZOVD;  Q5LH50, NUOCD_BACFN;  Q64Y08, NUOCD_BACFR;
DR   Q8A0F6, NUOCD_BACTN;  A6L169, NUOCD_BACV8;  Q1LT91, NUOCD_BAUCH;
DR   Q6MIR5, NUOCD_BDEBA;  Q7VRV4, NUOCD_BLOFL;  Q492H8, NUOCD_BLOPB;
DR   B8D8V7, NUOCD_BUCA5;  P57254, NUOCD_BUCAI;  Q8K9Y5, NUOCD_BUCAP;
DR   B8D761, NUOCD_BUCAT;  Q89AU4, NUOCD_BUCBP;  Q057X3, NUOCD_BUCCC;
DR   A0RMD1, NUOCD_CAMFF;  Q1QST4, NUOCD_CHRSD;  A8ADV3, NUOCD_CITK8;
DR   A7ZPA0, NUOCD_ECO24;  B7UFU4, NUOCD_ECO27;  B7MG50, NUOCD_ECO45;
DR   B7LAU8, NUOCD_ECO55;  Q8XCW9, NUOCD_ECO57;  B5YXS6, NUOCD_ECO5E;
DR   B7NNW5, NUOCD_ECO7I;  B7MXG5, NUOCD_ECO81;  B7M5W5, NUOCD_ECO8A;
DR   B1X8Z8, NUOCD_ECODH;  A8A2F5, NUOCD_ECOHS;  A1ADD4, NUOCD_ECOK1;
DR   Q0TFG0, NUOCD_ECOL5;  Q8FFJ7, NUOCD_ECOL6;  B1IXQ6, NUOCD_ECOLC;
DR   P33599, NUOCD_ECOLI;  B7N5P8, NUOCD_ECOLU;  B6I7N6, NUOCD_ECOSE;
DR   B1LLN9, NUOCD_ECOSM;  Q1R9D1, NUOCD_ECOUT;  C5B8I4, NUOCD_EDWI9;
DR   A4WCR5, NUOCD_ENT38;  A7MH24, NUOCD_ENTS8;  Q6D2R9, NUOCD_ERWCT;
DR   B2VIV5, NUOCD_ERWT9;  B7LM46, NUOCD_ESCF3;  A9HN95, NUOCD_GLUDA;
DR   D4GVF7, NUOCD_HALVD;  B4U8I3, NUOCD_HYDS0;  B5XNV6, NUOCD_KLEP3;
DR   A6TBX2, NUOCD_KLEP7;  Q608X9, NUOCD_METCA;  Q2YAA3, NUOCD_NITMU;
DR   Q3JC17, NUOCD_NITOC;  C6DA44, NUOCD_PECCP;  Q7N2I9, NUOCD_PHOLL;
DR   B4EZC8, NUOCD_PROMH;  Q48H52, NUOCD_PSE14;  A6V4E7, NUOCD_PSEA7;
DR   Q02ND1, NUOCD_PSEAB;  Q9I0J9, NUOCD_PSEAE;  Q1I7Z8, NUOCD_PSEE4;
DR   Q4K9T4, NUOCD_PSEF5;  C3JY83, NUOCD_PSEFS;  A4XV04, NUOCD_PSEMY;
DR   A5W190, NUOCD_PSEP1;  Q3KA61, NUOCD_PSEPF;  B0KMY0, NUOCD_PSEPG;
DR   Q88FH5, NUOCD_PSEPK;  B1J6N2, NUOCD_PSEPW;  Q87ZQ7, NUOCD_PSESM;
DR   Q4ZRJ1, NUOCD_PSEU2;  Q4FU62, NUOCD_PSYA2;  Q1QD95, NUOCD_PSYCK;
DR   A5WG46, NUOCD_PSYWF;  Q2J0F1, NUOCD_RHOP2;  Q07QX3, NUOCD_RHOP5;
DR   Q6N1Z0, NUOCD_RHOPA;  Q20Z41, NUOCD_RHOPB;  Q13BH3, NUOCD_RHOPS;
DR   B3Q6T3, NUOCD_RHOPT;  A3PKI2, NUOCD_RHOS1;  Q3J1Q7, NUOCD_RHOS4;
DR   A4WT70, NUOCD_RHOS5;  B9KJI1, NUOCD_RHOSK;  B5EZK7, NUOCD_SALA4;
DR   A9MJ99, NUOCD_SALAR;  Q57M30, NUOCD_SALCH;  B5FPG7, NUOCD_SALDC;
DR   B5R307, NUOCD_SALEP;  B5RCF1, NUOCD_SALG2;  B4TBJ2, NUOCD_SALHS;
DR   B4SYZ7, NUOCD_SALNS;  Q5PN53, NUOCD_SALPA;  A9N582, NUOCD_SALPB;
DR   C0Q041, NUOCD_SALPC;  B5BCM0, NUOCD_SALPK;  B4TPK8, NUOCD_SALSV;
DR   P0A1Y7, NUOCD_SALTI;  P0A1Y6, NUOCD_SALTY;  A8GH14, NUOCD_SERP5;
DR   Q8EI31, NUOCD_SHEON;  B1KJV0, NUOCD_SHEWM;  B2TW67, NUOCD_SHIB3;
DR   Q31YH5, NUOCD_SHIBS;  Q32DQ3, NUOCD_SHIDS;  Q0T2K1, NUOCD_SHIF8;
DR   Q83QS6, NUOCD_SHIFL;  Q3YZS4, NUOCD_SHISS;  Q2NSK1, NUOCD_SODGM;
DR   B2V8J2, NUOCD_SULSY;  A1JLG6, NUOCD_YERE8;  A7FGQ7, NUOCD_YERP3;
DR   Q1C6B1, NUOCD_YERPA;  B2K819, NUOCD_YERPB;  Q7CJ92, NUOCD_YERPE;
DR   A9R6L8, NUOCD_YERPG;  Q1CHQ3, NUOCD_YERPN;  A4TM34, NUOCD_YERPP;
DR   Q669A2, NUOCD_YERPS;  B1JGL5, NUOCD_YERPY;  A1TLL8, NUOC_ACIAC ;
DR   A0LRI3, NUOC_ACIC1 ;  B7J7U3, NUOC_ACIF2 ;  B5EN69, NUOC_ACIF5 ;
DR   A1W4M4, NUOC_ACISJ ;  B9JD44, NUOC_AGRRK ;  A9CJB1, NUOC_AGRT5 ;
DR   B9JVE7, NUOC_AGRVS ;  Q0A777, NUOC_ALHEH ;  Q5P1E8, NUOC_AROAE ;
DR   A8I3Y9, NUOC_AZOC5 ;  A1K5B0, NUOC_AZOSB ;  A1USW9, NUOC_BARBK ;
DR   Q6G390, NUOC_BARHE ;  Q6FZY9, NUOC_BARQU ;  A9IUQ0, NUOC_BART1 ;
DR   Q2KV11, NUOC_BORA1 ;  Q7WCU1, NUOC_BORBR ;  Q7W5A9, NUOC_BORPA ;
DR   A9II05, NUOC_BORPD ;  Q7VZQ3, NUOC_BORPE ;  B2S545, NUOC_BRUA1 ;
DR   Q2YNC7, NUOC_BRUA2 ;  Q57DU9, NUOC_BRUAB ;  A9MAI1, NUOC_BRUC2 ;
DR   C0RIE1, NUOC_BRUMB ;  Q8YGK2, NUOC_BRUME ;  A5VPY5, NUOC_BRUO2 ;
DR   B0CLD1, NUOC_BRUSI ;  Q8G1B5, NUOC_BRUSU ;  B1YTQ5, NUOC_BURA4 ;
DR   Q1BV15, NUOC_BURCA ;  B1JVN9, NUOC_BURCC ;  A0K921, NUOC_BURCH ;
DR   B4E5M0, NUOC_BURCJ ;  Q0BDD2, NUOC_BURCM ;  A9AFY9, NUOC_BURM1 ;
DR   A3MIA3, NUOC_BURM7 ;  A2S457, NUOC_BURM9 ;  Q62IN7, NUOC_BURMA ;
DR   A1V2L8, NUOC_BURMS ;  A3NTA8, NUOC_BURP0 ;  Q3JUA7, NUOC_BURP1 ;
DR   A3N7L9, NUOC_BURP6 ;  B2JDM6, NUOC_BURP8 ;  B2T2E9, NUOC_BURPP ;
DR   Q63VN1, NUOC_BURPS ;  Q39EE7, NUOC_BURS3 ;  Q2SZN3, NUOC_BURTA ;
DR   A4JGC8, NUOC_BURVG ;  Q142H1, NUOC_BURXL ;  Q9A6X2, NUOC_CAUCR ;
DR   B0SZ50, NUOC_CAUSK ;  A1BF34, NUOC_CHLPD ;  B3QY46, NUOC_CHLT3 ;
DR   Q7NZH9, NUOC_CHRVO ;  A9KBK6, NUOC_COXBN ;  A9N8X1, NUOC_COXBR ;
DR   Q83BQ7, NUOC_COXBU ;  Q0KCS8, NUOC_CUPNH ;  Q473U1, NUOC_CUPPJ ;
DR   B3R3W9, NUOC_CUPTR ;  Q47HH4, NUOC_DECAR ;  Q1IZX1, NUOC_DEIGD ;
DR   Q9RU88, NUOC_DEIRA ;  A9BNB2, NUOC_DELAS ;  A8LIT7, NUOC_DINSH ;
DR   Q2NA62, NUOC_ERYLH ;  B0TWP6, NUOC_FRAP2 ;  Q14K36, NUOC_FRAT1 ;
DR   A7NEK8, NUOC_FRATF ;  Q2A1F2, NUOC_FRATH ;  B2SEV1, NUOC_FRATM ;
DR   A0Q8H0, NUOC_FRATN ;  Q0BK53, NUOC_FRATO ;  Q5NIN3, NUOC_FRATT ;
DR   A4IVZ4, NUOC_FRATW ;  B5EFG1, NUOC_GEOBB ;  B3E9W7, NUOC_GEOLS ;
DR   Q39QA9, NUOC_GEOMG ;  Q74GA6, NUOC_GEOSL ;  A5G9B7, NUOC_GEOUR ;
DR   A1WXW5, NUOC_HALHL ;  A9B4Z6, NUOC_HERA2 ;  A4G642, NUOC_HERAR ;
DR   Q0C1E5, NUOC_HYPNA ;  A6SY07, NUOC_JANMA ;  Q28T74, NUOC_JANSC ;
DR   C1DCA5, NUOC_LARHH ;  Q5X1A9, NUOC_LEGPA ;  A5IHW1, NUOC_LEGPC ;
DR   Q5ZRU0, NUOC_LEGPH ;  Q5WT22, NUOC_LEGPL ;  B1Y829, NUOC_LEPCP ;
DR   Q2W3I6, NUOC_MAGSA ;  Q0APY8, NUOC_MARMM ;  Q11JK4, NUOC_MESSB ;
DR   A9W1N1, NUOC_METEP ;  Q1GZL1, NUOC_METFK ;  B1ZA44, NUOC_METPB ;
DR   A2SFM8, NUOC_METPP ;  B1LUN5, NUOC_METRJ ;  B0ULK6, NUOC_METS4 ;
DR   Q2RJU5, NUOC_MOOTA ;  A0QJU9, NUOC_MYCA1 ;  B1MPG6, NUOC_MYCA9 ;
DR   P65572, NUOC_MYCBO ;  A1KNE3, NUOC_MYCBP ;  C1AGR4, NUOC_MYCBT ;
DR   A4TDC0, NUOC_MYCGI ;  B2HGE6, NUOC_MYCMM ;  Q73V13, NUOC_MYCPA ;
DR   A0QU34, NUOC_MYCS2 ;  A3PWR9, NUOC_MYCSJ ;  A1UDA2, NUOC_MYCSK ;
DR   Q1BBP5, NUOC_MYCSS ;  A5U7G3, NUOC_MYCTA ;  P65571, NUOC_MYCTU ;
DR   A0PR40, NUOC_MYCUA ;  A1T6A4, NUOC_MYCVP ;  Q5F617, NUOC_NEIG1 ;
DR   B4RPI2, NUOC_NEIG2 ;  A9M3E0, NUOC_NEIM0 ;  Q9JX80, NUOC_NEIMA ;
DR   Q9K1C1, NUOC_NEIMB ;  A1KRS4, NUOC_NEIMF ;  Q2GDX8, NUOC_NEOSM ;
DR   Q0AHJ8, NUOC_NITEC ;  Q82TU5, NUOC_NITEU ;  Q2YA25, NUOC_NITMU ;
DR   Q3J830, NUOC_NITOC ;  Q5YWC9, NUOC_NOCFA ;  A1SE29, NUOC_NOCSJ ;
DR   Q2G5Y5, NUOC_NOVAD ;  A6X1N2, NUOC_OCHA4 ;  A7HY47, NUOC_PARL1 ;
DR   B4RCM7, NUOC_PHEZH ;  A1VM62, NUOC_POLNA ;  B1XUK0, NUOC_POLNS ;
DR   Q127X4, NUOC_POLSJ ;  A4SXQ1, NUOC_POLSQ ;  Q1LPW1, NUOC_RALME ;
DR   B2U7Q9, NUOC_RALPJ ;  Q8XXQ3, NUOC_RALSO ;  Q2K9T3, NUOC_RHIEC ;
DR   Q1MIL3, NUOC_RHIL3 ;  Q98KQ7, NUOC_RHILO ;  B5ZYL4, NUOC_RHILW ;
DR   O84971, NUOC_RHOCA ;  Q21YC5, NUOC_RHOFD ;  Q6N5M4, NUOC_RHOPA ;
DR   Q215I2, NUOC_RHOPB ;  B3Q7N4, NUOC_RHOPT ;  Q2RU38, NUOC_RHORT ;
DR   A3PIX0, NUOC_RHOS1 ;  Q3J3F9, NUOC_RHOS4 ;  A4WU32, NUOC_RHOS5 ;
DR   B9KQW2, NUOC_RHOSK ;  Q0S448, NUOC_RHOSR ;  Q1RJI7, NUOC_RICBR ;
DR   Q92ID7, NUOC_RICCN ;  Q4UM07, NUOC_RICFE ;  Q9ZDH3, NUOC_RICPR ;
DR   Q68X18, NUOC_RICTY ;  A7NIW0, NUOC_ROSCS ;  Q163Q2, NUOC_ROSDO ;
DR   A5UZH8, NUOC_ROSS1 ;  A1AVR4, NUOC_RUTMC ;  A4FPT9, NUOC_SACEN ;
DR   A8M620, NUOC_SALAI ;  A4XC36, NUOC_SALTO ;  Q5LPR5, NUOC_SILPO ;
DR   Q1GIP0, NUOC_SILST ;  A6U7W5, NUOC_SINMW ;  Q9XAQ6, NUOC_STRCO ;
DR   B4SQT4, NUOC_STRM5 ;  B2FNX7, NUOC_STRMK ;  Q72GD0, NUOC_THET2 ;
DR   Q31HF8, NUOC_THICR ;  Q3SEX6, NUOC_THIDA ;  B8GNY7, NUOC_THISH ;
DR   A1WLP2, NUOC_VEREI ;  A5CXF9, NUOC_VESOH ;  Q5GT42, NUOC_WOLTR ;
DR   Q8PJ42, NUOC_XANAC ;  Q3BRN1, NUOC_XANC5 ;  Q4UWB6, NUOC_XANC8 ;
DR   B0RRA0, NUOC_XANCB ;  Q8P7T4, NUOC_XANCP ;  Q2P0V7, NUOC_XANOM ;
DR   B2SVL7, NUOC_XANOP ;  Q5GXT3, NUOC_XANOR ;  A7IPA5, NUOC_XANP2 ;
DR   B2I786, NUOC_XYLF2 ;  Q9PGJ3, NUOC_XYLFA ;  B0U1W7, NUOC_XYLFM ;
DR   Q87EQ3, NUOC_XYLFT ;  Q1IS59, NUOD1_ACIBL;  Q2IL06, NUOD1_ANADE;
DR   A7H9U8, NUOD1_ANADF;  B4UIA2, NUOD1_ANASK;  B2IHW4, NUOD1_BEII9;
DR   A9WED7, NUOD1_CHLAA;  B3QUS0, NUOD1_CHLT3;  Q11XR6, NUOD1_CYTH3;
DR   A9B4Z7, NUOD1_HERA2;  Q1QP34, NUOD1_NITHX;  B1ZRT0, NUOD1_OPITP;
DR   B3PW00, NUOD1_RHIE6;  Q2K9T1, NUOD1_RHIEC;  P56907, NUOD1_RHIME;
DR   A7NIV9, NUOD1_ROSCS;  A5UXK3, NUOD1_ROSS1;  A8M619, NUOD1_SALAI;
DR   A4XC35, NUOD1_SALTO;  A6U7W6, NUOD1_SINMW;  Q02CU0, NUOD1_SOLUE;
DR   A9GUZ1, NUOD1_SORC5;  Q82DX8, NUOD1_STRAW;  Q9X853, NUOD1_STRCO;
DR   B1W516, NUOD1_STRGG;  B4SJH6, NUOD1_STRM5;  Q67P19, NUOD1_SYMTH;
DR   B5YKI5, NUOD1_THEYD;  Q1IS35, NUOD2_ACIBL;  Q2IL16, NUOD2_ANADE;
DR   A7H9V5, NUOD2_ANADF;  B4UIA9, NUOD2_ANASK;  B2ILG7, NUOD2_BEII9;
DR   A9WFB4, NUOD2_CHLAA;  B3QY45, NUOD2_CHLT3;  Q11VB5, NUOD2_CYTH3;
DR   A9B480, NUOD2_HERA2;  Q1QL87, NUOD2_NITHX;  B1ZUJ2, NUOD2_OPITP;
DR   B3PY59, NUOD2_RHIE6;  Q2K3U2, NUOD2_RHIEC;  P56908, NUOD2_RHIME;
DR   A7NL07, NUOD2_ROSCS;  A5UZH7, NUOD2_ROSS1;  A8M8F6, NUOD2_SALAI;
DR   A4XCQ7, NUOD2_SALTO;  A6UFK4, NUOD2_SINMW;  Q01UN9, NUOD2_SOLUE;
DR   A9G9T3, NUOD2_SORC5;  Q82ED7, NUOD2_STRAW;  Q9XAQ7, NUOD2_STRCO;
DR   B1VSH7, NUOD2_STRGG;  B4SQT3, NUOD2_STRM5;  Q67KN9, NUOD2_SYMTH;
DR   B5YL34, NUOD2_THEYD;  A1TLL9, NUOD_ACIAC ;  A0LRI4, NUOD_ACIC1 ;
DR   A5FX11, NUOD_ACICJ ;  B5EN68, NUOD_ACIF5 ;  A1W4M5, NUOD_ACISJ ;
DR   A9CJA9, NUOD_AGRT5 ;  B2ULZ0, NUOD_AKKM8 ;  Q0A778, NUOD_ALHEH ;
DR   B3ES55, NUOD_AMOA5 ;  Q5PAR3, NUOD_ANAMM ;  Q2GJY9, NUOD_ANAPZ ;
DR   Q5P1E7, NUOD_AROAE ;  A8I3Z3, NUOD_AZOC5 ;  A1K5B1, NUOD_AZOSB ;
DR   A0RL88, NUOD_BACAH ;  Q81K03, NUOD_BACAN ;  Q72XF6, NUOD_BACC1 ;
DR   A7GV48, NUOD_BACCN ;  Q814W9, NUOD_BACCR ;  Q630V1, NUOD_BACCZ ;
DR   Q6HAY8, NUOD_BACHK ;  A9VS95, NUOD_BACWK ;  A1USX0, NUOD_BARBK ;
DR   Q6G391, NUOD_BARHE ;  Q6FZY8, NUOD_BARQU ;  A9IUP7, NUOD_BART1 ;
DR   Q2KV09, NUOD_BORA1 ;  Q7WCU2, NUOD_BORBR ;  Q7W5B0, NUOD_BORPA ;
DR   A9II07, NUOD_BORPD ;  Q7VZQ2, NUOD_BORPE ;  Q89KI9, NUOD_BRAJA ;
DR   A5EK97, NUOD_BRASB ;  A4YVK9, NUOD_BRASO ;  B2S546, NUOD_BRUA1 ;
DR   Q2YNG0, NUOD_BRUA2 ;  Q57DU8, NUOD_BRUAB ;  A9MAI2, NUOD_BRUC2 ;
DR   Q8YGK3, NUOD_BRUME ;  A5VPY6, NUOD_BRUO2 ;  B0CLD2, NUOD_BRUSI ;
DR   Q8G1B4, NUOD_BRUSU ;  B1YTQ4, NUOD_BURA4 ;  Q1BV16, NUOD_BURCA ;
DR   B1JVN8, NUOD_BURCC ;  A0K920, NUOD_BURCH ;  B4E5L9, NUOD_BURCJ ;
DR   Q0BDD3, NUOD_BURCM ;  A9AFZ0, NUOD_BURM1 ;  A3MIA4, NUOD_BURM7 ;
DR   A2S456, NUOD_BURM9 ;  Q62IN8, NUOD_BURMA ;  A1V2L9, NUOD_BURMS ;
DR   A3NTA9, NUOD_BURP0 ;  Q3JUA6, NUOD_BURP1 ;  A3N7M0, NUOD_BURP6 ;
DR   B2JDM5, NUOD_BURP8 ;  B2T2F0, NUOD_BURPP ;  Q63VN0, NUOD_BURPS ;
DR   Q39EE8, NUOD_BURS3 ;  Q2SZN2, NUOD_BURTA ;  A4JGC7, NUOD_BURVG ;
DR   Q142H0, NUOD_BURXL ;  A8Z6E5, NUOD_CAMC1 ;  A7GW67, NUOD_CAMC5 ;
DR   A7HZV1, NUOD_CAMHC ;  A8FNN4, NUOD_CAMJ8 ;  A7H5S8, NUOD_CAMJD ;
DR   Q9PM99, NUOD_CAMJE ;  A1W1H5, NUOD_CAMJJ ;  Q5HSL5, NUOD_CAMJR ;
DR   Q3AC80, NUOD_CARHZ ;  Q9A6X4, NUOD_CAUCR ;  B0SZ49, NUOD_CAUSK ;
DR   Q3ASW5, NUOD_CHLCH ;  B3EI96, NUOD_CHLL2 ;  B3QP55, NUOD_CHLP8 ;
DR   B3EK98, NUOD_CHLPB ;  A1BF35, NUOD_CHLPD ;  Q8KEC0, NUOD_CHLTE ;
DR   Q7NZH8, NUOD_CHRVO ;  A6LXQ2, NUOD_CLOB8 ;  B6J697, NUOD_COXB1 ;
DR   B6IZ48, NUOD_COXB2 ;  A9KBK7, NUOD_COXBN ;  A9N8X0, NUOD_COXBR ;
DR   Q83BQ8, NUOD_COXBU ;  Q0KCS7, NUOD_CUPNH ;  Q473U0, NUOD_CUPPJ ;
DR   B3R3X0, NUOD_CUPTR ;  Q47HH3, NUOD_DECAR ;  Q3Z7Z8, NUOD_DEHE1 ;
DR   A5FQY6, NUOD_DEHSB ;  Q3ZXR8, NUOD_DEHSC ;  Q1IZX0, NUOD_DEIGD ;
DR   Q9RU89, NUOD_DEIRA ;  A9BNB1, NUOD_DELAS ;  Q24UB8, NUOD_DESHY ;
DR   Q6ANM7, NUOD_DESPS ;  A4J657, NUOD_DESRM ;  A8LIT9, NUOD_DINSH ;
DR   Q3YS37, NUOD_EHRCJ ;  Q2GGK7, NUOD_EHRCR ;  Q5FGV3, NUOD_EHRRG ;
DR   Q5HB88, NUOD_EHRRW ;  Q2NA64, NUOD_ERYLH ;  A5FKI7, NUOD_FLAJ1 ;
DR   A6H1R1, NUOD_FLAPJ ;  Q0RRW5, NUOD_FRAAA ;  B0TWP7, NUOD_FRAP2 ;
DR   Q2JFL7, NUOD_FRASC ;  A8LC98, NUOD_FRASN ;  Q14K35, NUOD_FRAT1 ;
DR   A7NEK7, NUOD_FRATF ;  Q2A1F3, NUOD_FRATH ;  B2SEV2, NUOD_FRATM ;
DR   A0Q8G9, NUOD_FRATN ;  Q0BK54, NUOD_FRATO ;  Q5NIN2, NUOD_FRATT ;
DR   A4IVZ5, NUOD_FRATW ;  B5EFG0, NUOD_GEOBB ;  Q5KUJ8, NUOD_GEOKA ;
DR   B3E9W6, NUOD_GEOLS ;  Q39QB0, NUOD_GEOMG ;  Q74GA5, NUOD_GEOSL ;
DR   A4ITI4, NUOD_GEOTN ;  A5G9B6, NUOD_GEOUR ;  A9HRT9, NUOD_GLUDA ;
DR   Q0BSK5, NUOD_GRABC ;  A1WXW4, NUOD_HALHL ;  Q17Z55, NUOD_HELAH ;
DR   Q7VFS5, NUOD_HELHP ;  B0TH80, NUOD_HELMI ;  B6JNA3, NUOD_HELP2 ;
DR   B5Z8Q8, NUOD_HELPG ;  Q1CRZ8, NUOD_HELPH ;  Q9ZJW4, NUOD_HELPJ ;
DR   B2UV27, NUOD_HELPS ;  O25853, NUOD_HELPY ;  A4G641, NUOD_HERAR ;
DR   Q0C1E4, NUOD_HYPNA ;  A6SY08, NUOD_JANMA ;  Q28T72, NUOD_JANSC ;
DR   Q5X1B0, NUOD_LEGPA ;  A5IHW0, NUOD_LEGPC ;  Q5ZRU1, NUOD_LEGPH ;
DR   Q5WT23, NUOD_LEGPL ;  B0SFT7, NUOD_LEPBA ;  Q04V69, NUOD_LEPBJ ;
DR   Q04YA7, NUOD_LEPBL ;  B0SP85, NUOD_LEPBP ;  B1Y830, NUOD_LEPCP ;
DR   Q72NT5, NUOD_LEPIC ;  Q8F7Q2, NUOD_LEPIN ;  Q2W3I7, NUOD_MAGSA ;
DR   A0LDS4, NUOD_MAGSM ;  Q0APY7, NUOD_MARMM ;  Q11JK3, NUOD_MESSB ;
DR   A9W1N0, NUOD_METEP ;  Q1GZL2, NUOD_METFK ;  B3DXN7, NUOD_METI4 ;
DR   B1ZA43, NUOD_METPB ;  A2SFM9, NUOD_METPP ;  B1LUN4, NUOD_METRJ ;
DR   B0ULK7, NUOD_METS4 ;  Q2RJU4, NUOD_MOOTA ;  A0QJV0, NUOD_MYCA1 ;
DR   B1MPG7, NUOD_MYCA9 ;  P65570, NUOD_MYCBO ;  A1KNE4, NUOD_MYCBP ;
DR   A4TDA8, NUOD_MYCGI ;  B2HGE5, NUOD_MYCMM ;  Q73V12, NUOD_MYCPA ;
DR   A0QU33, NUOD_MYCS2 ;  A3PWR8, NUOD_MYCSJ ;  A1UDA1, NUOD_MYCSK ;
DR   Q1BBP6, NUOD_MYCSS ;  A5U7G4, NUOD_MYCTA ;  P65569, NUOD_MYCTU ;
DR   A0PR41, NUOD_MYCUA ;  A1T6A3, NUOD_MYCVP ;  Q1D8S7, NUOD_MYXXD ;
DR   Q5F618, NUOD_NEIG1 ;  B4RPI1, NUOD_NEIG2 ;  A9M3D9, NUOD_NEIM0 ;
DR   A1INN7, NUOD_NEIMA ;  Q9K1C0, NUOD_NEIMB ;  A1KRS5, NUOD_NEIMF ;
DR   Q2GDJ8, NUOD_NEOSM ;  Q0AHJ7, NUOD_NITEC ;  Q82TU6, NUOD_NITEU ;
DR   Q2YA24, NUOD_NITMU ;  Q3J831, NUOD_NITOC ;  A6Q1P6, NUOD_NITSB ;
DR   Q3SRE6, NUOD_NITWN ;  Q5YWD0, NUOD_NOCFA ;  A1SE30, NUOD_NOCSJ ;
DR   Q2G5Y6, NUOD_NOVAD ;  A6X1N0, NUOD_OCHA4 ;  B6JGW3, NUOD_OLICO ;
DR   A5CES2, NUOD_ORITB ;  B3CSH1, NUOD_ORITI ;  A1B495, NUOD_PARDP ;
DR   A7HY46, NUOD_PARL1 ;  Q6MDR3, NUOD_PARUW ;  Q3B4W0, NUOD_PELLD ;
DR   B4SBZ0, NUOD_PELPB ;  A1ALP2, NUOD_PELPD ;  Q4FM88, NUOD_PELUB ;
DR   B4RCM6, NUOD_PHEZH ;  A1VM63, NUOD_POLNA ;  B1XUK1, NUOD_POLNS ;
DR   Q127X5, NUOD_POLSJ ;  A4SXQ0, NUOD_POLSQ ;  B4S754, NUOD_PROA2 ;
DR   Q6A6G1, NUOD_PROAC ;  A4SF45, NUOD_PROVI ;  Q1LPW0, NUOD_RALME ;
DR   B2U7Q8, NUOD_RALPJ ;  Q1MIL2, NUOD_RHIL3 ;  Q98KQ8, NUOD_RHILO ;
DR   B5ZYL5, NUOD_RHILW ;  O07310, NUOD_RHOCA ;  B6ISX8, NUOD_RHOCS ;
DR   Q21YC4, NUOD_RHOFD ;  Q2IWY2, NUOD_RHOP2 ;  Q07NM3, NUOD_RHOP5 ;
DR   Q6N5M5, NUOD_RHOPA ;  Q215I0, NUOD_RHOPB ;  Q135X7, NUOD_RHOPS ;
DR   B3Q7N3, NUOD_RHOPT ;  Q2RU37, NUOD_RHORT ;  A3PIX1, NUOD_RHOS1 ;
DR   Q3J3F8, NUOD_RHOS4 ;  A4WU31, NUOD_RHOS5 ;  Q0S447, NUOD_RHOSR ;
DR   A8GN50, NUOD_RICAH ;  A8GX80, NUOD_RICB8 ;  Q1RJI9, NUOD_RICBR ;
DR   A8EZ86, NUOD_RICCK ;  Q92ID8, NUOD_RICCN ;  Q4UM08, NUOD_RICFE ;
DR   A8F1C5, NUOD_RICM5 ;  Q9ZDH4, NUOD_RICPR ;  B0BX71, NUOD_RICRO ;
DR   A8GRR5, NUOD_RICRS ;  Q68X19, NUOD_RICTY ;  Q163Q5, NUOD_ROSDO ;
DR   Q1AVI6, NUOD_RUBXD ;  A1AVR5, NUOD_RUTMC ;  A4FPT8, NUOD_SACEN ;
DR   Q2S5J0, NUOD_SALRD ;  Q5LPR7, NUOD_SILPO ;  Q1GIN9, NUOD_SILST ;
DR   Q1GTK0, NUOD_SPHAL ;  A5VAM0, NUOD_SPHWW ;  B2FNX6, NUOD_STRMK ;
DR   Q30PI1, NUOD_SULDN ;  A6QCG0, NUOD_SULNB ;  A0LEQ1, NUOD_SYNFM ;
DR   Q47LE7, NUOD_THEFY ;  A6LMC4, NUOD_THEM4 ;  Q72GD1, NUOD_THET2 ;
DR   Q31HF7, NUOD_THICR ;  Q3SJQ4, NUOD_THIDA ;  A1WLP1, NUOD_VEREI ;
DR   A5CXG0, NUOD_VESOH ;  Q73HJ8, NUOD_WOLPM ;  B3CLH1, NUOD_WOLPP ;
DR   Q7MA48, NUOD_WOLSU ;  Q5GTF8, NUOD_WOLTR ;  Q8PJ43, NUOD_XANAC ;
DR   Q3BRN2, NUOD_XANC5 ;  Q4UWB5, NUOD_XANC8 ;  B0RRA1, NUOD_XANCB ;
DR   Q8P7T5, NUOD_XANCP ;  Q2P0V8, NUOD_XANOM ;  B2SVL6, NUOD_XANOP ;
DR   Q5GXT4, NUOD_XANOR ;  A7IPA4, NUOD_XANP2 ;  B2I787, NUOD_XYLF2 ;
DR   Q9PGJ2, NUOD_XYLFA ;  B0U1W8, NUOD_XYLFM ;  Q87EQ2, NUOD_XYLFT ;
DR   P56909, NUOE1_RHIME;  P56910, NUOE2_RHIME;  O66842, NUOE_AQUAE ;
DR   P57255, NUOE_BUCAI ;  Q8K9Y4, NUOE_BUCAP ;  Q89AU3, NUOE_BUCBP ;
DR   P0AFD2, NUOE_ECOL6 ;  P0AFD1, NUOE_ECOLI ;  P65574, NUOE_MYCBO ;
DR   P65573, NUOE_MYCTU ;  Q9I0J8, NUOE_PSEAE ;  Q1RJJ1, NUOE_RICBR ;
DR   Q92ID9, NUOE_RICCN ;  Q4UM09, NUOE_RICFE ;  Q9ZDH5, NUOE_RICPR ;
DR   Q68X20, NUOE_RICTY ;  P0A1Y9, NUOE_SALTI ;  P0A1Y8, NUOE_SALTY ;
DR   P0AFD3, NUOE_SHIFL ;  P56912, NUOF1_RHIME;  P56913, NUOF2_RHIME;
DR   O66841, NUOF_AQUAE ;  P57256, NUOF_BUCAI ;  Q8K9Y3, NUOF_BUCAP ;
DR   Q89AU2, NUOF_BUCBP ;  P31979, NUOF_ECOLI ;  P65568, NUOF_MYCBO ;
DR   P65567, NUOF_MYCTU ;  Q9I0J7, NUOF_PSEAE ;  O07948, NUOF_RHOCA ;
DR   A8GM77, NUOF_RICAH ;  A8GYE0, NUOF_RICB8 ;  Q1RHA0, NUOF_RICBR ;
DR   A8EXI1, NUOF_RICCK ;  Q92JB2, NUOF_RICCN ;  Q4UKA6, NUOF_RICFE ;
DR   A8F0M0, NUOF_RICM5 ;  Q9ZE33, NUOF_RICPR ;  A8GQT6, NUOF_RICRS ;
DR   Q68XY3, NUOF_RICTY ;  P33901, NUOF_SALTY ;  Q9XAQ9, NUOF_STRCO ;
DR   P56914, NUOG2_RHIME;  Q7VRV7, NUOG_BLOFL ;  P57257, NUOG_BUCAI ;
DR   Q8K9Y2, NUOG_BUCAP ;  Q89AU1, NUOG_BUCBP ;  Q8XCX2, NUOG_ECO57 ;
DR   Q8FFJ9, NUOG_ECOL6 ;  P33602, NUOG_ECOLI ;  P59962, NUOG_MYCBO ;
DR   P95175, NUOG_MYCTU ;  Q9I0J6, NUOG_PSEAE ;  Q9KGW3, NUOG_PSEFL ;
DR   Q88FH2, NUOG_PSEPK ;  Q87ZQ4, NUOG_PSESM ;  Q1RKD2, NUOG_RICBR ;
DR   Q92G92, NUOG_RICCN ;  Q4UK22, NUOG_RICFE ;  Q9ZCF6, NUOG_RICPR ;
DR   Q68VV2, NUOG_RICTY ;  P0A1Y5, NUOG_SALTI ;  P0A1Y4, NUOG_SALTY ;
DR   Q8EI34, NUOG_SHEON ;  Q7UC56, NUOG_SHIFL ;  Q9XAR0, NUOG_STRCO ;
DR   Q8ZDL2, NUOG_YERPE ;  Q1IS58, NUOH1_ACIBL;  Q11VB9, NUOH1_CYTH3;
DR   Q39ZB6, NUOH1_GEOMG;  Q74GA1, NUOH1_GEOSL;  Q2YA99, NUOH1_NITMU;
DR   Q3JC21, NUOH1_NITOC;  Q2K9S5, NUOH1_RHIEC;  Q92QP5, NUOH1_RHIME;
DR   Q2J0E7, NUOH1_RHOP2;  Q07QW9, NUOH1_RHOP5;  Q6N5N1, NUOH1_RHOPA;
DR   Q215H3, NUOH1_RHOPB;  Q13BG9, NUOH1_RHOPS;  A3PIX8, NUOH1_RHOS1;
DR   Q3J3F1, NUOH1_RHOS4;  Q02CT6, NUOH1_SOLUE;  Q67P15, NUOH1_SYMTH;
DR   A0LEQ2, NUOH1_SYNFM;  Q1IS40, NUOH2_ACIBL;  Q11RU2, NUOH2_CYTH3;
DR   Q39QB4, NUOH2_GEOMG;  Q746T2, NUOH2_GEOSL;  Q2YA20, NUOH2_NITMU;
DR   Q3J835, NUOH2_NITOC;  Q2K3T6, NUOH2_RHIEC;  Q9EV66, NUOH2_RHIME;
DR   Q2IWX6, NUOH2_RHOP2;  Q07NL6, NUOH2_RHOP5;  Q6N1Z4, NUOH2_RHOPA;
DR   Q20Z45, NUOH2_RHOPB;  Q135Y3, NUOH2_RHOPS;  A3PKI6, NUOH2_RHOS1;
DR   Q3J1Q3, NUOH2_RHOS4;  Q01UN2, NUOH2_SOLUE;  Q67KP0, NUOH2_SYMTH;
DR   A0LJM4, NUOH2_SYNFM;  Q5YWD4, NUOHI_NOCFA;  A1TLM3, NUOH_ACIAC ;
DR   Q6FE65, NUOH_ACIAD ;  A3M2Q4, NUOH_ACIBT ;  A0LRI8, NUOH_ACIC1 ;
DR   A1W4M9, NUOH_ACISJ ;  A0KJ61, NUOH_AERHH ;  A4SLN8, NUOH_AERS4 ;
DR   B9JD51, NUOH_AGRRK ;  Q8UFX0, NUOH_AGRT5 ;  B9JVF3, NUOH_AGRVS ;
DR   Q0A782, NUOH_ALHEH ;  Q2IL15, NUOH_ANADE ;  Q5PAQ2, NUOH_ANAMM ;
DR   Q2GK09, NUOH_ANAPZ ;  B7GME7, NUOH_ANOFW ;  O67336, NUOH_AQUAE ;
DR   Q5P1E3, NUOH_AROAE ;  B6YR61, NUOH_AZOPC ;  A1K5B5, NUOH_AZOSB ;
DR   C1DL20, NUOH_AZOVD ;  C3P1E5, NUOH_BACAA ;  C3LFH0, NUOH_BACAC ;
DR   A0RL87, NUOH_BACAH ;  Q81K04, NUOH_BACAN ;  B7JGM1, NUOH_BACC0 ;
DR   Q72XF7, NUOH_BACC1 ;  B7IQU9, NUOH_BACC2 ;  C1F0L9, NUOH_BACC3 ;
DR   B7HFJ2, NUOH_BACC4 ;  B7HY54, NUOH_BACC7 ;  A7GV47, NUOH_BACCN ;
DR   B9IRS8, NUOH_BACCQ ;  Q814X0, NUOH_BACCR ;  Q630V2, NUOH_BACCZ ;
DR   Q5LH51, NUOH_BACFN ;  Q64Y09, NUOH_BACFR ;  Q6HAY9, NUOH_BACHK ;
DR   Q8A0F7, NUOH_BACTN ;  A6L168, NUOH_BACV8 ;  A9VS94, NUOH_BACWK ;
DR   A1USX4, NUOH_BARBK ;  Q6G395, NUOH_BARHE ;  Q6FZY4, NUOH_BARQU ;
DR   A9IUN6, NUOH_BART1 ;  Q1LT95, NUOH_BAUCH ;  Q6MGN3, NUOH_BDEBA ;
DR   Q7VRV8, NUOH_BLOFL ;  Q492I2, NUOH_BLOPB ;  Q2KUZ9, NUOH_BORA1 ;
DR   Q7WCU6, NUOH_BORBR ;  Q7W5B4, NUOH_BORPA ;  A9II17, NUOH_BORPD ;
DR   Q7VZP8, NUOH_BORPE ;  Q89KJ5, NUOH_BRAJA ;  A5EK91, NUOH_BRASB ;
DR   A4YVK3, NUOH_BRASO ;  C0Z769, NUOH_BREBN ;  Q2YNF6, NUOH_BRUA2 ;
DR   Q57DU4, NUOH_BRUAB ;  A9MAI6, NUOH_BRUC2 ;  C0RIE6, NUOH_BRUMB ;
DR   Q8YGK7, NUOH_BRUME ;  A5VPZ0, NUOH_BRUO2 ;  B0CLD6, NUOH_BRUSI ;
DR   Q8G1B0, NUOH_BRUSU ;  B8D8W1, NUOH_BUCA5 ;  P57258, NUOH_BUCAI ;
DR   Q8K9Y1, NUOH_BUCAP ;  B8D765, NUOH_BUCAT ;  Q89AU0, NUOH_BUCBP ;
DR   B1YTQ0, NUOH_BURA4 ;  Q1BV20, NUOH_BURCA ;  B1JVN4, NUOH_BURCC ;
DR   A0K916, NUOH_BURCH ;  B4E5L5, NUOH_BURCJ ;  Q0BDD7, NUOH_BURCM ;
DR   A9AFZ4, NUOH_BURM1 ;  Q62IP2, NUOH_BURMA ;  A3NTB3, NUOH_BURP0 ;
DR   Q3JUA2, NUOH_BURP1 ;  A3N7M4, NUOH_BURP6 ;  B2JDM1, NUOH_BURP8 ;
DR   B2T2F4, NUOH_BURPP ;  Q63VM6, NUOH_BURPS ;  Q39EF2, NUOH_BURS3 ;
DR   Q2SZM8, NUOH_BURTA ;  A4JGC3, NUOH_BURVG ;  Q142G6, NUOH_BURXL ;
DR   A7ZBE9, NUOH_CAMC1 ;  A7GW63, NUOH_CAMC5 ;  A7HZV5, NUOH_CAMHC ;
DR   A8FNN0, NUOH_CAMJ8 ;  A7H5S4, NUOH_CAMJD ;  Q9PMA3, NUOH_CAMJE ;
DR   A1W1H1, NUOH_CAMJJ ;  Q5HSL9, NUOH_CAMJR ;  Q3AC81, NUOH_CARHZ ;
DR   Q9A6Y1, NUOH_CAUCR ;  Q3ASW4, NUOH_CHLCH ;  B3QP54, NUOH_CHLP8 ;
DR   A1BF36, NUOH_CHLPD ;  Q8KEB9, NUOH_CHLTE ;  Q1QST8, NUOH_CHRSD ;
DR   Q7NZH4, NUOH_CHRVO ;  A8ADV7, NUOH_CITK8 ;  B6J6A2, NUOH_COXB1 ;
DR   B6IZ52, NUOH_COXB2 ;  A9KBL2, NUOH_COXBN ;  A9N8W5, NUOH_COXBR ;
DR   Q83BR2, NUOH_COXBU ;  Q0KCS3, NUOH_CUPNH ;  Q473T6, NUOH_CUPPJ ;
DR   B3R3X4, NUOH_CUPTR ;  Q47HG9, NUOH_DECAR ;  Q3Z7Z7, NUOH_DEHE1 ;
DR   Q3ZXR7, NUOH_DEHSC ;  C1D0H8, NUOH_DEIDV ;  Q1IZW6, NUOH_DEIGD ;
DR   Q9RU94, NUOH_DEIRA ;  Q24UB9, NUOH_DESHY ;  Q6ANM8, NUOH_DESPS ;
DR   A8LIU9, NUOH_DINSH ;  A7ZP96, NUOH_ECO24 ;  B7UFU0, NUOH_ECO27 ;
DR   B7MG46, NUOH_ECO45 ;  B7LAU4, NUOH_ECO55 ;  P0AFD5, NUOH_ECO57 ;
DR   B5YXS2, NUOH_ECO5E ;  B7NNW1, NUOH_ECO7I ;  B7MXW1, NUOH_ECO81 ;
DR   B7M5W1, NUOH_ECO8A ;  C4ZUC5, NUOH_ECOBW ;  B1X8Z4, NUOH_ECODH ;
DR   A8A2F1, NUOH_ECOHS ;  A1ADD0, NUOH_ECOK1 ;  Q0TFG4, NUOH_ECOL5 ;
DR   Q8FFK0, NUOH_ECOL6 ;  B1IXR0, NUOH_ECOLC ;  P0AFD4, NUOH_ECOLI ;
DR   B7N5P4, NUOH_ECOLU ;  B6I7N2, NUOH_ECOSE ;  B1LLN5, NUOH_ECOSM ;
DR   Q1R9D5, NUOH_ECOUT ;  C5B8I0, NUOH_EDWI9 ;  Q3YS40, NUOH_EHRCJ ;
DR   Q2GGK6, NUOH_EHRCR ;  Q5FGW5, NUOH_EHRRG ;  Q5HB99, NUOH_EHRRW ;
DR   A4WCR1, NUOH_ENT38 ;  A7MPB4, NUOH_ENTS8 ;  Q6D2S3, NUOH_ERWCT ;
DR   B2VIV9, NUOH_ERWT9 ;  Q2NA73, NUOH_ERYLH ;  B7LM50, NUOH_ESCF3 ;
DR   A5FKK0, NUOH_FLAJ1 ;  A6H1Q6, NUOH_FLAPJ ;  Q0RRW1, NUOH_FRAAA ;
DR   B0TWQ1, NUOH_FRAP2 ;  Q2JFL3, NUOH_FRASC ;  Q14K31, NUOH_FRAT1 ;
DR   A7NEK3, NUOH_FRATF ;  Q2A1F7, NUOH_FRATH ;  B2SEV6, NUOH_FRATM ;
DR   A0Q8G5, NUOH_FRATN ;  Q0BK58, NUOH_FRATO ;  Q5NIM8, NUOH_FRATT ;
DR   A4IVZ9, NUOH_FRATW ;  Q5KUJ9, NUOH_GEOKA ;  C5D984, NUOH_GEOSW ;
DR   A4ITI3, NUOH_GEOTN ;  Q0BSK9, NUOH_GRABC ;  A1WXW0, NUOH_HALHL ;
DR   Q17Z59, NUOH_HELAH ;  Q7VFS9, NUOH_HELHP ;  B6JNA7, NUOH_HELP2 ;
DR   B5Z8R2, NUOH_HELPG ;  Q1CRZ4, NUOH_HELPH ;  Q9ZJW0, NUOH_HELPJ ;
DR   B2UV31, NUOH_HELPS ;  O25857, NUOH_HELPY ;  A4G637, NUOH_HERAR ;
DR   Q0C1D7, NUOH_HYPNA ;  A6SY12, NUOH_JANMA ;  Q28T60, NUOH_JANSC ;
DR   B5XNW0, NUOH_KLEP3 ;  A6TBW8, NUOH_KLEP7 ;  Q5X1B4, NUOH_LEGPA ;
DR   A5IHV6, NUOH_LEGPC ;  Q5ZRU5, NUOH_LEGPH ;  Q5WT27, NUOH_LEGPL ;
DR   B0SFU0, NUOH_LEPBA ;  Q04V66, NUOH_LEPBJ ;  Q04YB0, NUOH_LEPBL ;
DR   B0SP88, NUOH_LEPBP ;  Q72NT2, NUOH_LEPIC ;  Q8F7Q5, NUOH_LEPIN ;
DR   Q2W3J1, NUOH_MAGSA ;  A0LDS0, NUOH_MAGSM ;  Q0APY3, NUOH_MARMM ;
DR   Q11JJ9, NUOH_MESSB ;  Q608Y3, NUOH_METCA ;  Q1GZL6, NUOH_METFK ;
DR   A2SFN3, NUOH_METPP ;  Q2RJU3, NUOH_MOOTA ;  A0QJV4, NUOH_MYCA1 ;
DR   P65562, NUOH_MYCBO ;  A1KNE8, NUOH_MYCBP ;  C1AGR9, NUOH_MYCBT ;
DR   A4TDB2, NUOH_MYCGI ;  Q73V08, NUOH_MYCPA ;  A0QU29, NUOH_MYCS2 ;
DR   A3PWR4, NUOH_MYCSJ ;  A1UD97, NUOH_MYCSK ;  Q1BBQ0, NUOH_MYCSS ;
DR   A5U7G8, NUOH_MYCTA ;  P65561, NUOH_MYCTU ;  A0PR45, NUOH_MYCUA ;
DR   A1T699, NUOH_MYCVP ;  Q5F622, NUOH_NEIG1 ;  A9M3D4, NUOH_NEIM0 ;
DR   Q9JX88, NUOH_NEIMA ;  Q9K1B4, NUOH_NEIMB ;  A1KRT0, NUOH_NEIMF ;
DR   Q2GEZ1, NUOH_NEOSM ;  Q0AHJ3, NUOH_NITEC ;  Q82TV0, NUOH_NITEU ;
DR   Q1QL92, NUOH_NITHX ;  A6Q1Q1, NUOH_NITSB ;  Q3SRF1, NUOH_NITWN ;
DR   A1SE34, NUOH_NOCSJ ;  Q2G5Z3, NUOH_NOVAD ;  A6X1M6, NUOH_OCHA4 ;
DR   A5CFN5, NUOH_ORITB ;  B3CUK2, NUOH_ORITI ;  A1B487, NUOH_PARDP ;
DR   A7HY42, NUOH_PARL1 ;  Q6MDQ9, NUOH_PARUW ;  C6DA40, NUOH_PECCP ;
DR   Q3A821, NUOH_PELCD ;  Q3B4V9, NUOH_PELLD ;  Q4FM84, NUOH_PELUB ;
DR   B4RCM1, NUOH_PHEZH ;  Q7N2J3, NUOH_PHOLL ;  A1VM67, NUOH_POLNA ;
DR   Q127X9, NUOH_POLSJ ;  Q6A6G5, NUOH_PROAC ;  B4EZC4, NUOH_PROMH ;
DR   Q48H48, NUOH_PSE14 ;  A6V4E2, NUOH_PSEA7 ;  B7VAQ9, NUOH_PSEA8 ;
DR   Q02ND5, NUOH_PSEAB ;  Q9I0J5, NUOH_PSEAE ;  Q1I7Z4, NUOH_PSEE4 ;
DR   Q4K9T0, NUOH_PSEF5 ;  C3JY87, NUOH_PSEFS ;  A4XV08, NUOH_PSEMY ;
DR   A5W186, NUOH_PSEP1 ;  Q3KA57, NUOH_PSEPF ;  B0KMY4, NUOH_PSEPG ;
DR   Q88FH1, NUOH_PSEPK ;  B1J6M8, NUOH_PSEPW ;  Q87ZQ3, NUOH_PSESM ;
DR   Q4ZRI7, NUOH_PSEU2 ;  Q4FU58, NUOH_PSYA2 ;  Q1QD91, NUOH_PSYCK ;
DR   A5WG42, NUOH_PSYWF ;  Q1LPV6, NUOH_RALME ;  B2U7Q4, NUOH_RALPJ ;
DR   Q8XXQ8, NUOH_RALSO ;  Q1MIK7, NUOH_RHIL3 ;  Q98KR3, NUOH_RHILO ;
DR   B5ZYM1, NUOH_RHILW ;  P42032, NUOH_RHOCA ;  B6ISX4, NUOH_RHOCS ;
DR   Q21YC0, NUOH_RHOFD ;  Q2RU33, NUOH_RHORT ;  Q0S443, NUOH_RHOSR ;
DR   C3PLS6, NUOH_RICAE ;  A8GPY7, NUOH_RICAH ;  A8GY33, NUOH_RICB8 ;
DR   Q1RKD1, NUOH_RICBR ;  A8EZZ9, NUOH_RICCK ;  Q92G93, NUOH_RICCN ;
DR   Q4UK23, NUOH_RICFE ;  Q9ZCF7, NUOH_RICPR ;  C4K222, NUOH_RICPU ;
DR   B0BVB1, NUOH_RICRO ;  A8GTS1, NUOH_RICRS ;  Q68VV3, NUOH_RICTY ;
DR   Q163R6, NUOH_ROSDO ;  Q1AVI7, NUOH_RUBXD ;  A1AVR9, NUOH_RUTMC ;
DR   A4FPT4, NUOH_SACEN ;  B5EZK3, NUOH_SALA4 ;  A9MJA3, NUOH_SALAR ;
DR   Q57M34, NUOH_SALCH ;  B5FPG3, NUOH_SALDC ;  B4SYZ3, NUOH_SALNS ;
DR   Q5PN59, NUOH_SALPA ;  A9N586, NUOH_SALPB ;  C0Q045, NUOH_SALPC ;
DR   Q2RYV5, NUOH_SALRD ;  Q8Z527, NUOH_SALTI ;  Q60010, NUOH_SALTY ;
DR   A8GH10, NUOH_SERP5 ;  Q8EI35, NUOH_SHEON ;  B2TW63, NUOH_SHIB3 ;
DR   Q31YH9, NUOH_SHIBS ;  Q32DQ7, NUOH_SHIDS ;  Q0T2K5, NUOH_SHIF8 ;
DR   Q83QS9, NUOH_SHIFL ;  Q3YZS8, NUOH_SHISS ;  Q5LPS7, NUOH_SILPO ;
DR   Q1GIN0, NUOH_SILST ;  Q2NSK5, NUOH_SODGM ;  Q1GTK6, NUOH_SPHAL ;
DR   A5VAM7, NUOH_SPHWW ;  Q82DX4, NUOH_STRAW ;  Q9XAR1, NUOH_STRCO ;
DR   Q30PI6, NUOH_SULDN ;  Q47LF1, NUOH_THEFY ;  B9L173, NUOH_THERP ;
DR   Q72GD5, NUOH_THET2 ;  Q31HF3, NUOH_THICR ;  Q3SJQ0, NUOH_THIDA ;
DR   A1WLN7, NUOH_VEREI ;  A5CXG4, NUOH_VESOH ;  Q73IK1, NUOH_WOLPM ;
DR   Q7MA43, NUOH_WOLSU ;  Q5GSR1, NUOH_WOLTR ;  Q8PJ47, NUOH_XANAC ;
DR   Q3BRN6, NUOH_XANC5 ;  Q4UWB1, NUOH_XANC8 ;  B0RRA5, NUOH_XANCB ;
DR   Q8P7T9, NUOH_XANCP ;  Q2P0W2, NUOH_XANOM ;  B2SVL2, NUOH_XANOP ;
DR   Q5GXT9, NUOH_XANOR ;  B2I791, NUOH_XYLF2 ;  Q9PGI8, NUOH_XYLFA ;
DR   B0U1X2, NUOH_XYLFM ;  Q87EP8, NUOH_XYLFT ;  A1JLH7, NUOH_YERE8 ;
DR   A7FGR0, NUOH_YERP3 ;  Q1C6B5, NUOH_YERPA ;  B2K815, NUOH_YERPB ;
DR   Q8ZDL3, NUOH_YERPE ;  A9R6L5, NUOH_YERPG ;  Q1CHQ7, NUOH_YERPN ;
DR   A4TM30, NUOH_YERPP ;  Q669A6, NUOH_YERPS ;  B1JGL9, NUOH_YERPY ;
DR   Q1IS57, NUOI1_ACIBL;  Q2IL01, NUOI1_ANADE;  O67337, NUOI1_AQUAE;
DR   Q39ZB4, NUOI1_GEOMG;  Q74GA0, NUOI1_GEOSL;  Q744Z4, NUOI1_MYCPA;
DR   Q2YA98, NUOI1_NITMU;  Q3JC22, NUOI1_NITOC;  Q2K9S4, NUOI1_RHIEC;
DR   Q92QP4, NUOI1_RHIME;  Q2J0E6, NUOI1_RHOP2;  Q07QW8, NUOI1_RHOP5;
DR   Q6N5N2, NUOI1_RHOPA;  Q215H2, NUOI1_RHOPB;  Q13BG8, NUOI1_RHOPS;
DR   A3PIX9, NUOI1_RHOS1;  Q3J3F0, NUOI1_RHOS4;  Q01ZR8, NUOI1_SOLUE;
DR   Q82DX3, NUOI1_STRAW;  Q9XAR2, NUOI1_STRCO;  Q67P14, NUOI1_SYMTH;
DR   A0LEQ3, NUOI1_SYNFM;  Q1IQK4, NUOI2_ACIBL;  Q2IL14, NUOI2_ANADE;
DR   O67386, NUOI2_AQUAE;  Q39QB5, NUOI2_GEOMG;  Q746T4, NUOI2_GEOSL;
DR   Q73V07, NUOI2_MYCPA;  Q2YA19, NUOI2_NITMU;  Q3J836, NUOI2_NITOC;
DR   Q2K3T7, NUOI2_RHIEC;  Q92YN8, NUOI2_RHIME;  Q2IWX5, NUOI2_RHOP2;
DR   Q07NL5, NUOI2_RHOP5;  Q6N1Z5, NUOI2_RHOPA;  Q20Z46, NUOI2_RHOPB;
DR   Q135Y4, NUOI2_RHOPS;  A3PKI7, NUOI2_RHOS1;  Q3J1Q2, NUOI2_RHOS4;
DR   Q01UN8, NUOI2_SOLUE;  Q82DT3, NUOI2_STRAW;  Q9F2V8, NUOI2_STRCO;
DR   Q67KP1, NUOI2_SYMTH;  A0LJM3, NUOI2_SYNFM;  A1TLM4, NUOI_ACIAC ;
DR   Q6FE64, NUOI_ACIAD ;  B2HU48, NUOI_ACIBC ;  B0VU49, NUOI_ACIBS ;
DR   A3M2Q5, NUOI_ACIBT ;  B0V894, NUOI_ACIBY ;  A0LRI9, NUOI_ACIC1 ;
DR   A1W4N0, NUOI_ACISJ ;  A0KJ60, NUOI_AERHH ;  A4SLN7, NUOI_AERS4 ;
DR   Q8UFW9, NUOI_AGRT5 ;  B9JVF4, NUOI_AGRVS ;  Q0A783, NUOI_ALHEH ;
DR   A7H9V8, NUOI_ANADF ;  Q5PAK7, NUOI_ANAMM ;  Q2GJS3, NUOI_ANAPZ ;
DR   Q5P1E2, NUOI_AROAE ;  A8I407, NUOI_AZOC5 ;  A1K5B6, NUOI_AZOSB ;
DR   A1USX5, NUOI_BARBK ;  Q6G396, NUOI_BARHE ;  Q6FZY3, NUOI_BARQU ;
DR   A9IUN3, NUOI_BART1 ;  Q1LT96, NUOI_BAUCH ;  Q6MIR9, NUOI_BDEBA ;
DR   B2IHV8, NUOI_BEII9 ;  Q7VRV9, NUOI_BLOFL ;  Q492I3, NUOI_BLOPB ;
DR   Q2KUZ8, NUOI_BORA1 ;  Q7WCU7, NUOI_BORBR ;  Q7W5B5, NUOI_BORPA ;
DR   Q7VZP7, NUOI_BORPE ;  Q89KJ6, NUOI_BRAJA ;  A5EK90, NUOI_BRASB ;
DR   A4YVK2, NUOI_BRASO ;  B2S551, NUOI_BRUA1 ;  Q2YNF5, NUOI_BRUA2 ;
DR   Q57DU3, NUOI_BRUAB ;  A9MAI7, NUOI_BRUC2 ;  C0RIE7, NUOI_BRUMB ;
DR   Q8YGK8, NUOI_BRUME ;  A5VPZ1, NUOI_BRUO2 ;  B0CLD7, NUOI_BRUSI ;
DR   Q8G1A9, NUOI_BRUSU ;  P57259, NUOI_BUCAI ;  Q8K9Y0, NUOI_BUCAP ;
DR   Q89AT9, NUOI_BUCBP ;  Q057W8, NUOI_BUCCC ;  B1YTP9, NUOI_BURA4 ;
DR   Q1BV21, NUOI_BURCA ;  B1JVN3, NUOI_BURCC ;  A0K915, NUOI_BURCH ;
DR   B4E5L4, NUOI_BURCJ ;  Q0BDD8, NUOI_BURCM ;  A9AFZ5, NUOI_BURM1 ;
DR   A3MIA9, NUOI_BURM7 ;  A2S451, NUOI_BURM9 ;  Q62IP3, NUOI_BURMA ;
DR   A1V2M4, NUOI_BURMS ;  A3NTB4, NUOI_BURP0 ;  Q3JUA1, NUOI_BURP1 ;
DR   A3N7M5, NUOI_BURP6 ;  Q63VM5, NUOI_BURPS ;  Q39EF3, NUOI_BURS3 ;
DR   Q2SZM7, NUOI_BURTA ;  A4JGC2, NUOI_BURVG ;  Q142G5, NUOI_BURXL ;
DR   A0RMD6, NUOI_CAMFF ;  A7HZV6, NUOI_CAMHC ;  A8FNM9, NUOI_CAMJ8 ;
DR   A7H5S3, NUOI_CAMJD ;  Q0P857, NUOI_CAMJE ;  A1W1H0, NUOI_CAMJJ ;
DR   Q5HSM0, NUOI_CAMJR ;  Q3AC82, NUOI_CARHZ ;  Q9A6Y4, NUOI_CAUCR ;
DR   B3QSE2, NUOI_CHLT3 ;  Q1QST9, NUOI_CHRSD ;  Q7NZH3, NUOI_CHRVO ;
DR   A9KBL3, NUOI_COXBN ;  A9N8W4, NUOI_COXBR ;  Q83BR3, NUOI_COXBU ;
DR   Q0KCS2, NUOI_CUPNH ;  Q473T5, NUOI_CUPPJ ;  B3R3X5, NUOI_CUPTR ;
DR   Q11VC0, NUOI_CYTH3 ;  Q47HG8, NUOI_DECAR ;  C1D0H9, NUOI_DEIDV ;
DR   Q1IZW5, NUOI_DEIGD ;  Q9RU95, NUOI_DEIRA ;  A8LIV0, NUOI_DINSH ;
DR   P0AFD8, NUOI_ECO57 ;  A1ADC9, NUOI_ECOK1 ;  Q0TFG5, NUOI_ECOL5 ;
DR   P0AFD7, NUOI_ECOL6 ;  P0AFD6, NUOI_ECOLI ;  Q1R9D6, NUOI_ECOUT ;
DR   C5B8H9, NUOI_EDWI9 ;  Q3YSA1, NUOI_EHRCJ ;  Q2GGD7, NUOI_EHRCR ;
DR   Q5FHN1, NUOI_EHRRG ;  Q5HBF8, NUOI_EHRRW ;  A7MPB5, NUOI_ENTS8 ;
DR   Q6D2S4, NUOI_ERWCT ;  B2VIN2, NUOI_ERWT9 ;  Q2NA74, NUOI_ERYLH ;
DR   A6H1Q5, NUOI_FLAPJ ;  Q0RRW0, NUOI_FRAAA ;  B0TWQ2, NUOI_FRAP2 ;
DR   Q2JFL2, NUOI_FRASC ;  A8LC93, NUOI_FRASN ;  Q14K30, NUOI_FRAT1 ;
DR   A7NEK2, NUOI_FRATF ;  Q2A1F8, NUOI_FRATH ;  B2SEV7, NUOI_FRATM ;
DR   A0Q8G4, NUOI_FRATN ;  Q0BK59, NUOI_FRATO ;  Q5NIM7, NUOI_FRATT ;
DR   A4IW00, NUOI_FRATW ;  Q0BSL0, NUOI_GRABC ;  A1WXV9, NUOI_HALHL ;
DR   Q17Z60, NUOI_HELAH ;  Q7VFT0, NUOI_HELHP ;  B6JNA8, NUOI_HELP2 ;
DR   B5Z8R3, NUOI_HELPG ;  Q1CRZ3, NUOI_HELPH ;  Q9ZJV9, NUOI_HELPJ ;
DR   B2UV32, NUOI_HELPS ;  O25858, NUOI_HELPY ;  A4G636, NUOI_HERAR ;
DR   Q0C1D6, NUOI_HYPNA ;  Q28T58, NUOI_JANSC ;  Q5X1B5, NUOI_LEGPA ;
DR   A5IHV5, NUOI_LEGPC ;  Q5ZRU6, NUOI_LEGPH ;  Q5WT28, NUOI_LEGPL ;
DR   B0SHV5, NUOI_LEPBA ;  Q04W38, NUOI_LEPBJ ;  Q04XD4, NUOI_LEPBL ;
DR   B0SRH5, NUOI_LEPBP ;  Q72VZ9, NUOI_LEPIC ;  Q8F9N0, NUOI_LEPIN ;
DR   Q2W3J2, NUOI_MAGSA ;  A0LDR9, NUOI_MAGSM ;  Q0APY2, NUOI_MARMM ;
DR   Q11JJ8, NUOI_MESSB ;  B7KQ58, NUOI_METC4 ;  Q608Y4, NUOI_METCA ;
DR   A9W1M5, NUOI_METEP ;  Q1GZL7, NUOI_METFK ;  B8IUV4, NUOI_METNO ;
DR   B1ZA38, NUOI_METPB ;  A2SFN4, NUOI_METPP ;  B1LUM8, NUOI_METRJ ;
DR   B0ULL2, NUOI_METS4 ;  B8EIM5, NUOI_METSB ;  A0QJV5, NUOI_MYCA1 ;
DR   Q7TX57, NUOI_MYCBO ;  A1KNE9, NUOI_MYCBP ;  C1AGS0, NUOI_MYCBT ;
DR   A4TDB3, NUOI_MYCGI ;  B2HGE0, NUOI_MYCMM ;  A0QU28, NUOI_MYCS2 ;
DR   A3PWR3, NUOI_MYCSJ ;  A1UD96, NUOI_MYCSK ;  Q1BBQ1, NUOI_MYCSS ;
DR   A5U7G9, NUOI_MYCTA ;  P95173, NUOI_MYCTU ;  A0PR46, NUOI_MYCUA ;
DR   A1T698, NUOI_MYCVP ;  Q1D8T0, NUOI_MYXXD ;  Q5F623, NUOI_NEIG1 ;
DR   Q9JQM2, NUOI_NEIMA ;  Q7DDS1, NUOI_NEIMB ;  A1KRT1, NUOI_NEIMF ;
DR   Q2GCV4, NUOI_NEOSM ;  Q0AHJ2, NUOI_NITEC ;  Q82TV1, NUOI_NITEU ;
DR   Q1QL93, NUOI_NITHX ;  Q3SRF2, NUOI_NITWN ;  A1SE35, NUOI_NOCSJ ;
DR   Q2G5Z4, NUOI_NOVAD ;  A6X1M5, NUOI_OCHA4 ;  B6JH51, NUOI_OLICO ;
DR   A5CFN6, NUOI_ORITB ;  B3CUK1, NUOI_ORITI ;  A1B486, NUOI_PARDP ;
DR   A7HY41, NUOI_PARL1 ;  Q6MDQ8, NUOI_PARUW ;  Q3A820, NUOI_PELCD ;
DR   A1ALP7, NUOI_PELPD ;  Q4FM83, NUOI_PELUB ;  Q7N2J4, NUOI_PHOLL ;
DR   A1VM68, NUOI_POLNA ;  Q127Y0, NUOI_POLSJ ;  Q6A6G6, NUOI_PROAC ;
DR   B4EZC3, NUOI_PROMH ;  Q48H47, NUOI_PSE14 ;  A6V4E1, NUOI_PSEA7 ;
DR   B7VAQ8, NUOI_PSEA8 ;  Q02ND6, NUOI_PSEAB ;  Q9I0J4, NUOI_PSEAE ;
DR   Q1I7Z3, NUOI_PSEE4 ;  Q4K9S9, NUOI_PSEF5 ;  Q8RQ74, NUOI_PSEFL ;
DR   Q3KA56, NUOI_PSEPF ;  Q88FH0, NUOI_PSEPK ;  Q87ZQ2, NUOI_PSESM ;
DR   Q4ZRI6, NUOI_PSEU2 ;  Q4FU57, NUOI_PSYA2 ;  Q1QD90, NUOI_PSYCK ;
DR   Q1LPV5, NUOI_RALME ;  Q8XXQ9, NUOI_RALSO ;  Q1MIK6, NUOI_RHIL3 ;
DR   Q98KR4, NUOI_RHILO ;  B5ZYM2, NUOI_RHILW ;  P42031, NUOI_RHOCA ;
DR   B6ISX3, NUOI_RHOCS ;  C0ZYJ2, NUOI_RHOE4 ;  Q21YB9, NUOI_RHOFD ;
DR   C1AZF5, NUOI_RHOOB ;  Q2RU32, NUOI_RHORT ;  Q0S442, NUOI_RHOSR ;
DR   C3PLS5, NUOI_RICAE ;  A8GPY5, NUOI_RICAH ;  A8GY32, NUOI_RICB8 ;
DR   Q1RKD0, NUOI_RICBR ;  A8EZZ7, NUOI_RICCK ;  Q92G94, NUOI_RICCN ;
DR   Q4UK24, NUOI_RICFE ;  A8F2T4, NUOI_RICM5 ;  Q9ZCF8, NUOI_RICPR ;
DR   C4K221, NUOI_RICPU ;  B0BVB0, NUOI_RICRO ;  A8GTS0, NUOI_RICRS ;
DR   Q68VV4, NUOI_RICTY ;  Q163R7, NUOI_ROSDO ;  A1AVS0, NUOI_RUTMC ;
DR   A4FPT3, NUOI_SACEN ;  Q57M35, NUOI_SALCH ;  Q5PN58, NUOI_SALPA ;
DR   Q8XFD5, NUOI_SALTI ;  Q7CQ51, NUOI_SALTY ;  Q8EI36, NUOI_SHEON ;
DR   B1KJV5, NUOI_SHEWM ;  Q31YI0, NUOI_SHIBS ;  Q32DQ8, NUOI_SHIDS ;
DR   Q0T2K6, NUOI_SHIF8 ;  P0AFD9, NUOI_SHIFL ;  Q3YZS9, NUOI_SHISS ;
DR   Q5LPS9, NUOI_SILPO ;  Q1GIM9, NUOI_SILST ;  Q2NSK6, NUOI_SODGM ;
DR   Q1GTK7, NUOI_SPHAL ;  Q30PI7, NUOI_SULDN ;  Q47LF2, NUOI_THEFY ;
DR   Q72GD6, NUOI_THET2 ;  Q31HF2, NUOI_THICR ;  Q3SJP9, NUOI_THIDA ;
DR   C4LB38, NUOI_TOLAT ;  A1WLN6, NUOI_VEREI ;  A5CXG5, NUOI_VESOH ;
DR   Q73GH4, NUOI_WOLPM ;  Q7MA42, NUOI_WOLSU ;  Q5GSG5, NUOI_WOLTR ;
DR   Q8PJ48, NUOI_XANAC ;  Q3BRN7, NUOI_XANC5 ;  Q4UWB0, NUOI_XANC8 ;
DR   Q8P7U0, NUOI_XANCP ;  Q2P0W3, NUOI_XANOM ;  Q5GXU0, NUOI_XANOR ;
DR   A7IP99, NUOI_XANP2 ;  Q9PGI7, NUOI_XYLFA ;  Q87EP7, NUOI_XYLFT ;
DR   A1JLI2, NUOI_YERE8 ;  A7FGR1, NUOI_YERP3 ;  Q1C6B6, NUOI_YERPA ;
DR   B2K814, NUOI_YERPB ;  Q7CJ89, NUOI_YERPE ;  A9R6L4, NUOI_YERPG ;
DR   Q1CHQ8, NUOI_YERPN ;  A4TM29, NUOI_YERPP ;  Q669A7, NUOI_YERPS ;
DR   B1JGM0, NUOI_YERPY ;  P57260, NUOJ_BUCAI ;  Q8K9X9, NUOJ_BUCAP ;
DR   Q89AT8, NUOJ_BUCBP ;  P0AFE2, NUOJ_ECO57 ;  P0AFE1, NUOJ_ECOL6 ;
DR   P0AFE0, NUOJ_ECOLI ;  Q9I0J3, NUOJ_PSEAE ;  P50975, NUOJ_RHOCA ;
DR   Q1RKE8, NUOJ_RICBR ;  Q92G99, NUOJ_RICCN ;  Q4UK29, NUOJ_RICFE ;
DR   Q9ZCG3, NUOJ_RICPR ;  Q68VV9, NUOJ_RICTY ;  P0AFE3, NUOJ_SHIFL ;
DR   Q1IS55, NUOK1_ACIBL;  O67339, NUOK1_AQUAE;  B5E964, NUOK1_GEOBB;
DR   Q39ZB0, NUOK1_GEOMG;  B9LZM7, NUOK1_GEOSF;  Q74G98, NUOK1_GEOSL;
DR   C6E8U8, NUOK1_GEOSM;  A5GD03, NUOK1_GEOUR;  B3PW09, NUOK1_RHIE6;
DR   Q2K9S2, NUOK1_RHIEC;  Q92QP2, NUOK1_RHIME;  C3MA67, NUOK1_RHISN;
DR   Q6N5N4, NUOK1_RHOPA;  A6U7X5, NUOK1_SINMW;  Q02CT4, NUOK1_SOLUE;
DR   Q82DX1, NUOK1_STRAW;  Q9F2V6, NUOK1_STRCO;  B1W509, NUOK1_STRGG;
DR   Q67P12, NUOK1_SYMTH;  A0LEQ5, NUOK1_SYNFM;  Q1IS42, NUOK2_ACIBL;
DR   O67388, NUOK2_AQUAE;  B5EFF3, NUOK2_GEOBB;  Q39QB7, NUOK2_GEOMG;
DR   B9M3Y9, NUOK2_GEOSF;  Q746T6, NUOK2_GEOSL;  C6E8M5, NUOK2_GEOSM;
DR   A5G9A9, NUOK2_GEOUR;  B3PY50, NUOK2_RHIE6;  Q2K3V1, NUOK2_RHIEC;
DR   Q9EV71, NUOK2_RHIME;  C3MEY7, NUOK2_RHISN;  Q6N1Z7, NUOK2_RHOPA;
DR   A6UFL3, NUOK2_SINMW;  Q01UN6, NUOK2_SOLUE;  Q82DT1, NUOK2_STRAW;
DR   Q9XAR4, NUOK2_STRCO;  B1W4V4, NUOK2_STRGG;  Q67KP3, NUOK2_SYMTH;
DR   A0LJM1, NUOK2_SYNFM;  A1TLM6, NUOK_ACIAC ;  Q6FE62, NUOK_ACIAD ;
DR   B7GZB2, NUOK_ACIB3 ;  B7I748, NUOK_ACIB5 ;  B2HU50, NUOK_ACIBC ;
DR   B0VU47, NUOK_ACIBS ;  A3M2Q7, NUOK_ACIBT ;  B0V892, NUOK_ACIBY ;
DR   A0LRJ1, NUOK_ACIC1 ;  C1F9D3, NUOK_ACIC5 ;  A5FXJ1, NUOK_ACICJ ;
DR   B7J7T5, NUOK_ACIF2 ;  B5EN61, NUOK_ACIF5 ;  A0KJ58, NUOK_AERHH ;
DR   A4SLN5, NUOK_AERS4 ;  A9CJA4, NUOK_AGRT5 ;  B2ULY3, NUOK_AKKM8 ;
DR   Q0A785, NUOK_ALHEH ;  B8JBR1, NUOK_ANAD2 ;  Q2IHA4, NUOK_ANADE ;
DR   A7HIH8, NUOK_ANADF ;  B4UIW0, NUOK_ANASK ;  B7GME4, NUOK_ANOFW ;
DR   A8ERK6, NUOK_ARCB4 ;  Q5P1E0, NUOK_AROAE ;  A8I413, NUOK_AZOC5 ;
DR   A1K5B8, NUOK_AZOSB ;  C1DL23, NUOK_AZOVD ;  C3P1E2, NUOK_BACAA ;
DR   C3LFG7, NUOK_BACAC ;  Q81K07, NUOK_BACAN ;  B7JGL8, NUOK_BACC0 ;
DR   Q72XG0, NUOK_BACC1 ;  B7IQU6, NUOK_BACC2 ;  C1F0L6, NUOK_BACC3 ;
DR   B7HFI9, NUOK_BACC4 ;  B7HY51, NUOK_BACC7 ;  A7GV44, NUOK_BACCN ;
DR   B9IRS5, NUOK_BACCQ ;  Q814X3, NUOK_BACCR ;  Q630V5, NUOK_BACCZ ;
DR   Q6HAZ2, NUOK_BACHK ;  A9VS91, NUOK_BACWK ;  A1USX7, NUOK_BARBK ;
DR   C6ADP9, NUOK_BARGA ;  Q6G398, NUOK_BARHE ;  Q6FZY1, NUOK_BARQU ;
DR   A9IUM6, NUOK_BART1 ;  Q1LT98, NUOK_BAUCH ;  Q6MGN5, NUOK_BDEBA ;
DR   B2IHV6, NUOK_BEII9 ;  C5C0R7, NUOK_BEUC1 ;  Q7VRW1, NUOK_BLOFL ;
DR   Q492I5, NUOK_BLOPB ;  Q2KUZ4, NUOK_BORA1 ;  Q7WCU9, NUOK_BORBR ;
DR   Q7W5B7, NUOK_BORPA ;  A9II25, NUOK_BORPD ;  Q7VZP5, NUOK_BORPE ;
DR   A5EK88, NUOK_BRASB ;  A4YVK0, NUOK_BRASO ;  C0Z766, NUOK_BREBN ;
DR   B2S553, NUOK_BRUA1 ;  Q2YNF3, NUOK_BRUA2 ;  Q57DU1, NUOK_BRUAB ;
DR   A9MAI9, NUOK_BRUC2 ;  C0RIE9, NUOK_BRUMB ;  Q8YGL0, NUOK_BRUME ;
DR   A5VPZ3, NUOK_BRUO2 ;  B0CLD9, NUOK_BRUSI ;  Q8G1A7, NUOK_BRUSU ;
DR   B8D8W4, NUOK_BUCA5 ;  P57261, NUOK_BUCAI ;  Q8K9X8, NUOK_BUCAP ;
DR   B8D768, NUOK_BUCAT ;  Q89AT7, NUOK_BUCBP ;  Q057W6, NUOK_BUCCC ;
DR   B1YTP7, NUOK_BURA4 ;  Q1BV23, NUOK_BURCA ;  B1JVN1, NUOK_BURCC ;
DR   A0K913, NUOK_BURCH ;  B4E5L2, NUOK_BURCJ ;  Q0BDE0, NUOK_BURCM ;
DR   A9AFZ7, NUOK_BURM1 ;  A3MIB1, NUOK_BURM7 ;  A2S449, NUOK_BURM9 ;
DR   Q62IP5, NUOK_BURMA ;  A1V2M6, NUOK_BURMS ;  A3NTB6, NUOK_BURP0 ;
DR   Q3JU99, NUOK_BURP1 ;  A3N7M7, NUOK_BURP6 ;  B2JDL8, NUOK_BURP8 ;
DR   B2T2F7, NUOK_BURPP ;  Q63VM3, NUOK_BURPS ;  Q39EF5, NUOK_BURS3 ;
DR   Q2SZM5, NUOK_BURTA ;  A4JGC0, NUOK_BURVG ;  Q142G3, NUOK_BURXL ;
DR   A8Z6E7, NUOK_CAMC1 ;  A7GW60, NUOK_CAMC5 ;  A0RMD8, NUOK_CAMFF ;
DR   A7HZV8, NUOK_CAMHC ;  B8GWU1, NUOK_CAUCN ;  Q9A6Y6, NUOK_CAUCR ;
DR   A9WFC1, NUOK_CHLAA ;  B8G6Z6, NUOK_CHLAD ;  B3QP51, NUOK_CHLP8 ;
DR   B9LAV0, NUOK_CHLSY ;  B3QXL8, NUOK_CHLT3 ;  Q8KEB6, NUOK_CHLTE ;
DR   Q1QSU1, NUOK_CHRSD ;  Q7NZH1, NUOK_CHRVO ;  A8ADW0, NUOK_CITK8 ;
DR   B6J6A5, NUOK_COXB1 ;  B6IZ55, NUOK_COXB2 ;  A9KBL5, NUOK_COXBN ;
DR   A9N8W2, NUOK_COXBR ;  Q83BR5, NUOK_COXBU ;  Q0KCS0, NUOK_CUPNH ;
DR   Q473T3, NUOK_CUPPJ ;  B3R3X7, NUOK_CUPTR ;  Q11VC2, NUOK_CYTH3 ;
DR   Q47HG6, NUOK_DECAR ;  C1D0I1, NUOK_DEIDV ;  Q1IZW3, NUOK_DEIGD ;
DR   Q9RU97, NUOK_DEIRA ;  B8J1D0, NUOK_DESDA ;  B8FRK0, NUOK_DESHD ;
DR   Q24UC2, NUOK_DESHY ;  C4XMN4, NUOK_DESMR ;  C6C9P6, NUOK_DICDC ;
DR   C6CEF6, NUOK_DICZE ;  A7ZP93, NUOK_ECO24 ;  B7UFT7, NUOK_ECO27 ;
DR   B7MG43, NUOK_ECO45 ;  B7LAU1, NUOK_ECO55 ;  P0AFE6, NUOK_ECO57 ;
DR   B5YXR9, NUOK_ECO5E ;  B7NNV8, NUOK_ECO7I ;  B7MXV8, NUOK_ECO81 ;
DR   B7M5V8, NUOK_ECO8A ;  C5W716, NUOK_ECOBD ;  C6ULT8, NUOK_ECOBR ;
DR   C4ZUC2, NUOK_ECOBW ;  B1X8Z1, NUOK_ECODH ;  A8A2E8, NUOK_ECOHS ;
DR   A1ADC7, NUOK_ECOK1 ;  Q0TFG7, NUOK_ECOL5 ;  P0AFE5, NUOK_ECOL6 ;
DR   B1IXR3, NUOK_ECOLC ;  P0AFE4, NUOK_ECOLI ;  B7N5P1, NUOK_ECOLU ;
DR   B6I7M9, NUOK_ECOSE ;  B1LLN2, NUOK_ECOSM ;  Q1R9D8, NUOK_ECOUT ;
DR   C5B8H7, NUOK_EDWI9 ;  A4WCQ8, NUOK_ENT38 ;  A7MPB7, NUOK_ENTS8 ;
DR   Q6D2S6, NUOK_ERWCT ;  B2VIN4, NUOK_ERWT9 ;  B7LM53, NUOK_ESCF3 ;
DR   A5FKJ7, NUOK_FLAJ1 ;  A6H1Q3, NUOK_FLAPJ ;  Q0RRV8, NUOK_FRAAA ;
DR   B0TWQ4, NUOK_FRAP2 ;  Q2JFL0, NUOK_FRASC ;  A8LC91, NUOK_FRASN ;
DR   Q14K28, NUOK_FRAT1 ;  A7NEK0, NUOK_FRATF ;  Q2A1G0, NUOK_FRATH ;
DR   Q0BK61, NUOK_FRATO ;  Q5NIM5, NUOK_FRATT ;  C1A8Y4, NUOK_GEMAT ;
DR   Q5KUK3, NUOK_GEOKA ;  B3E9V9, NUOK_GEOLS ;  C5D981, NUOK_GEOSW ;
DR   A4ITI0, NUOK_GEOTN ;  A9HN78, NUOK_GLUDA ;  Q0BSL2, NUOK_GRABC ;
DR   C4K6N1, NUOK_HAMD5 ;  Q17Z62, NUOK_HELAH ;  Q7VFT2, NUOK_HELHP ;
DR   B6JNB0, NUOK_HELP2 ;  C7C0H5, NUOK_HELPB ;  B5Z8R5, NUOK_HELPG ;
DR   Q1CRZ1, NUOK_HELPH ;  Q9ZJV7, NUOK_HELPJ ;  B2UV34, NUOK_HELPS ;
DR   O25860, NUOK_HELPY ;  A9B6Y3, NUOK_HERA2 ;  B4U8I7, NUOK_HYDS0 ;
DR   B5XNW3, NUOK_KLEP3 ;  A6TBW5, NUOK_KLEP7 ;  C1DCB3, NUOK_LARHH ;
DR   Q5X1B7, NUOK_LEGPA ;  A5IHV3, NUOK_LEGPC ;  Q5ZRU8, NUOK_LEGPH ;
DR   Q5WT30, NUOK_LEGPL ;  B0SFU2, NUOK_LEPBA ;  Q04V64, NUOK_LEPBJ ;
DR   Q04YB2, NUOK_LEPBL ;  B0SP90, NUOK_LEPBP ;  B1XWB1, NUOK_LEPCP ;
DR   Q72NT0, NUOK_LEPIC ;  Q8F7Q7, NUOK_LEPIN ;  A0LDR7, NUOK_MAGSM ;
DR   Q11JJ6, NUOK_MESSB ;  Q608Y6, NUOK_METCA ;  B3DZT3, NUOK_METI4 ;
DR   C6WX51, NUOK_METML ;  B8IUV6, NUOK_METNO ;  A2SFN6, NUOK_METPP ;
DR   B0ULL4, NUOK_METS4 ;  B8EIM7, NUOK_METSB ;  C6XAJ7, NUOK_METSD ;
DR   A0QJV7, NUOK_MYCA1 ;  B1MPH4, NUOK_MYCA9 ;  P65566, NUOK_MYCBO ;
DR   A1KNF1, NUOK_MYCBP ;  C1AGS2, NUOK_MYCBT ;  A4TDA1, NUOK_MYCGI ;
DR   B2HGD8, NUOK_MYCMM ;  Q73V05, NUOK_MYCPA ;  A0QU26, NUOK_MYCS2 ;
DR   A3PWR1, NUOK_MYCSJ ;  A1UD94, NUOK_MYCSK ;  Q1BBQ3, NUOK_MYCSS ;
DR   A5U7H1, NUOK_MYCTA ;  P65565, NUOK_MYCTU ;  A0PR48, NUOK_MYCUA ;
DR   A1T696, NUOK_MYCVP ;  Q1DDD0, NUOK_MYXXD ;  Q5F625, NUOK_NEIG1 ;
DR   B4RPH4, NUOK_NEIG2 ;  A1INM7, NUOK_NEIMA ;  Q7DDS0, NUOK_NEIMB ;
DR   A1KRT3, NUOK_NEIMF ;  Q0AHJ0, NUOK_NITEC ;  Q82TV3, NUOK_NITEU ;
DR   Q1QL95, NUOK_NITHX ;  Q2YA96, NUOK_NITMU ;  Q3JC24, NUOK_NITOC ;
DR   A6Q1Q4, NUOK_NITSB ;  Q5YWD6, NUOK_NOCFA ;  A1SE37, NUOK_NOCSJ ;
DR   A6X1M3, NUOK_OCHA4 ;  B1ZRS3, NUOK_OPITP ;  A1B482, NUOK_PARDP ;
DR   A7HY39, NUOK_PARL1 ;  Q6MDQ6, NUOK_PARUW ;  C6DA37, NUOK_PECCP ;
DR   Q3A818, NUOK_PELCD ;  C0QR89, NUOK_PERMH ;  B4RCL8, NUOK_PHEZH ;
DR   Q7N2J6, NUOK_PHOLL ;  Q6A6G8, NUOK_PROAC ;  B4EZ50, NUOK_PROMH ;
DR   Q48H45, NUOK_PSE14 ;  A6V4D9, NUOK_PSEA7 ;  B7VAQ6, NUOK_PSEA8 ;
DR   Q02ND8, NUOK_PSEAB ;  Q9I0J2, NUOK_PSEAE ;  Q1I7Z1, NUOK_PSEE4 ;
DR   Q4K9S7, NUOK_PSEF5 ;  C3JY90, NUOK_PSEFS ;  A4XV11, NUOK_PSEMY ;
DR   A5W183, NUOK_PSEP1 ;  Q3KA54, NUOK_PSEPF ;  B0KMY7, NUOK_PSEPG ;
DR   Q88FG8, NUOK_PSEPK ;  B1J6S8, NUOK_PSEPW ;  Q87ZQ0, NUOK_PSESM ;
DR   Q4ZRI4, NUOK_PSEU2 ;  Q4FU55, NUOK_PSYA2 ;  Q1QD88, NUOK_PSYCK ;
DR   A5WG39, NUOK_PSYWF ;  Q1LPV3, NUOK_RALME ;  C6BJN9, NUOK_RALP1 ;
DR   B2U7Q1, NUOK_RALPJ ;  Q8XXR1, NUOK_RALSO ;  Q1MIK4, NUOK_RHIL3 ;
DR   Q98KR6, NUOK_RHILO ;  C6AUT0, NUOK_RHILS ;  B5ZYM4, NUOK_RHILW ;
DR   P50940, NUOK_RHOCA ;  B6ISX1, NUOK_RHOCS ;  C0ZYJ0, NUOK_RHOE4 ;
DR   Q21YB7, NUOK_RHOFD ;  C1AZF7, NUOK_RHOOB ;  Q2J0E4, NUOK_RHOP2 ;
DR   Q07QW6, NUOK_RHOP5 ;  Q20Z48, NUOK_RHOPB ;  Q13BG6, NUOK_RHOPS ;
DR   B3Q6S6, NUOK_RHOPT ;  A3PIY2, NUOK_RHOS1 ;  Q3J3E7, NUOK_RHOS4 ;
DR   A4WU21, NUOK_RHOS5 ;  B9KQX4, NUOK_RHOSK ;  Q0S440, NUOK_RHOSR ;
DR   Q1RKE7, NUOK_RICBR ;  Q92G98, NUOK_RICCN ;  Q4UK28, NUOK_RICFE ;
DR   Q9ZCG2, NUOK_RICPR ;  Q68VV8, NUOK_RICTY ;  A7NPD9, NUOK_ROSCS ;
DR   A5UVF9, NUOK_ROSS1 ;  Q1AVI9, NUOK_RUBXD ;  A1AVS2, NUOK_RUTMC ;
DR   A4FPT1, NUOK_SACEN ;  B5EZK0, NUOK_SALA4 ;  A8M612, NUOK_SALAI ;
DR   A9MJA6, NUOK_SALAR ;  Q57M37, NUOK_SALCH ;  B5FPG0, NUOK_SALDC ;
DR   B5R300, NUOK_SALEP ;  B5RCE4, NUOK_SALG2 ;  B4TBI5, NUOK_SALHS ;
DR   B4SYZ0, NUOK_SALNS ;  Q5PN65, NUOK_SALPA ;  A9N589, NUOK_SALPB ;
DR   C0Q048, NUOK_SALPC ;  B5BCM7, NUOK_SALPK ;  Q2S2L3, NUOK_SALRD ;
DR   B4TPK1, NUOK_SALSV ;  Q8XFA3, NUOK_SALTI ;  A4XC28, NUOK_SALTO ;
DR   Q7CQ53, NUOK_SALTY ;  A8GH07, NUOK_SERP5 ;  Q8EI38, NUOK_SHEON ;
DR   B1KJV7, NUOK_SHEWM ;  B2TW60, NUOK_SHIB3 ;  Q31YI2, NUOK_SHIBS ;
DR   Q32DR0, NUOK_SHIDS ;  Q0T2K8, NUOK_SHIF8 ;  P0AFE7, NUOK_SHIFL ;
DR   Q3YZT1, NUOK_SHISS ;  Q5LPT3, NUOK_SILPO ;  Q2NSK8, NUOK_SODGM ;
DR   A9EX69, NUOK_SORC5 ;  Q1GTK9, NUOK_SPHAL ;  B4SQS6, NUOK_STRM5 ;
DR   B2FN96, NUOK_STRMK ;  C1DT39, NUOK_SULAA ;  Q30PI9, NUOK_SULDN ;
DR   A6QCF2, NUOK_SULNB ;  B2V983, NUOK_SULSY ;  Q47LF4, NUOK_THEFY ;
DR   B9L175, NUOK_THERP ;  Q72GD8, NUOK_THET2 ;  B5YKI9, NUOK_THEYD ;
DR   Q3SJP7, NUOK_THIDA ;  B8GNZ5, NUOK_THISH ;  C4LB40, NUOK_TOLAT ;
DR   C5CT10, NUOK_VARPS ;  Q7MA40, NUOK_WOLSU ;  Q8NL19, NUOK_XANAC ;
DR   Q3BRN9, NUOK_XANC5 ;  Q4UWA8, NUOK_XANC8 ;  B0RRA8, NUOK_XANCB ;
DR   Q7CLR2, NUOK_XANCP ;  Q2P0W5, NUOK_XANOM ;  B2SVK9, NUOK_XANOP ;
DR   Q5GXU2, NUOK_XANOR ;  A7IP97, NUOK_XANP2 ;  Q9PGI5, NUOK_XYLFA ;
DR   Q87EP5, NUOK_XYLFT ;  A1JLI8, NUOK_YERE8 ;  A7FGR3, NUOK_YERP3 ;
DR   Q1C6B8, NUOK_YERPA ;  B2K812, NUOK_YERPB ;  Q7CJ87, NUOK_YERPE ;
DR   A9R6L2, NUOK_YERPG ;  Q1CHR0, NUOK_YERPN ;  A4TM27, NUOK_YERPP ;
DR   Q669A9, NUOK_YERPS ;  B1JGM2, NUOK_YERPY ;  P57262, NUOL_BUCAI ;
DR   Q8K9X7, NUOL_BUCAP ;  Q89AT6, NUOL_BUCBP ;  Q9PMA7, NUOL_CAMJE ;
DR   P33607, NUOL_ECOLI ;  O86350, NUOL_MYCTU ;  Q9JX92, NUOL_NEIMA ;
DR   Q9K1B0, NUOL_NEIMB ;  Q9I0J1, NUOL_PSEAE ;  P50939, NUOL_RHOCA ;
DR   Q1RKE6, NUOL_RICBR ;  Q92G97, NUOL_RICCN ;  Q4UK27, NUOL_RICFE ;
DR   Q9ZCG1, NUOL_RICPR ;  Q68VV7, NUOL_RICTY ;  Q9XAR5, NUOL_STRCO ;
DR   P57263, NUOM_BUCAI ;  Q8K9X6, NUOM_BUCAP ;  Q89AT5, NUOM_BUCBP ;
DR   P0AFE9, NUOM_ECO57 ;  P0AFE8, NUOM_ECOLI ;  O53307, NUOM_MYCTU ;
DR   Q9I0J0, NUOM_PSEAE ;  P50974, NUOM_RHOCA ;  Q1RKE5, NUOM_RICBR ;
DR   Q92G96, NUOM_RICCN ;  Q4UK26, NUOM_RICFE ;  Q9ZCG0, NUOM_RICPR ;
DR   Q68VV6, NUOM_RICTY ;  Q1IS52, NUON1_ACIBL;  C1F9D0, NUON1_ACIC5;
DR   A5FX21, NUON1_ACICJ;  O67342, NUON1_AQUAE;  B3QXM3, NUON1_CHLT3;
DR   C4XMN1, NUON1_DESMR;  A9B6Y0, NUON1_HERA2;  B4U8I1, NUON1_HYDS0;
DR   Q3JC27, NUON1_NITOC;  B1ZRS0, NUON1_OPITP;  Q92QN9, NUON1_RHIME;
DR   A7NL15, NUON1_ROSCS;  Q02CT1, NUON1_SOLUE;  A9EX55, NUON1_SORC5;
DR   B1VSR0, NUON1_STRGG;  Q67P10, NUON1_SYMTH;  A0LEQ8, NUON1_SYNFM;
DR   B5YKJ2, NUON1_THEYD;  Q1IS45, NUON2_ACIBL;  C1F223, NUON2_ACIC5;
DR   A5FXI8, NUON2_ACICJ;  O67391, NUON2_AQUAE;  B3QY38, NUON2_CHLT3;
DR   C4XGW8, NUON2_DESMR;  A9B488, NUON2_HERA2;  B4U8J0, NUON2_HYDS0;
DR   Q3J841, NUON2_NITOC;  B1ZUK1, NUON2_OPITP;  P56911, NUON2_RHIME;
DR   A7NPD6, NUON2_ROSCS;  Q01UN3, NUON2_SOLUE;  A9F575, NUON2_SORC5;
DR   B1W4V1, NUON2_STRGG;  Q67KP6, NUON2_SYMTH;  A0LJL8, NUON2_SYNFM;
DR   B5YL23, NUON2_THEYD;  B1W506, NUON3_STRGG;  B7I751, NUON_ACIB5 ;
DR   A0LRJ4, NUON_ACIC1 ;  B7J7T2, NUON_ACIF2 ;  A0KJ55, NUON_AERHH ;
DR   Q0A788, NUON_ALHEH ;  B8JAZ0, NUON_ANAD2 ;  A7H9U1, NUON_ANADF ;
DR   B9KIT6, NUON_ANAMF ;  Q2GKQ9, NUON_ANAPZ ;  B7GME1, NUON_ANOFW ;
DR   A8ERK3, NUON_ARCB4 ;  A8I421, NUON_AZOC5 ;  B6YQ48, NUON_AZOPC ;
DR   A1K5C1, NUON_AZOSB ;  Q81K10, NUON_BACAN ;  Q64Y15, NUON_BACFR ;
DR   A6L162, NUON_BACV8 ;  A1USY0, NUON_BARBK ;  Q1LTA1, NUON_BAUCH ;
DR   Q6MGN8, NUON_BDEBA ;  B2IHV3, NUON_BEII9 ;  C5C0R4, NUON_BEUC1 ;
DR   Q7VRW4, NUON_BLOFL ;  Q492I8, NUON_BLOPB ;  Q2KUY6, NUON_BORA1 ;
DR   C0Z763, NUON_BREBN ;  P57264, NUON_BUCAI ;  Q8K9X5, NUON_BUCAP ;
DR   Q89AT4, NUON_BUCBP ;  Q057W3, NUON_BUCCC ;  B2JDL5, NUON_BURP8 ;
DR   A7ZBF3, NUON_CAMC1 ;  A0RME1, NUON_CAMFF ;  A7HZW1, NUON_CAMHC ;
DR   Q5HSM5, NUON_CAMJR ;  B9KDV9, NUON_CAMLR ;  Q3AC87, NUON_CARHZ ;
DR   B0SZ35, NUON_CAUSK ;  B8G6L3, NUON_CHLAD ;  Q3ASV8, NUON_CHLCH ;
DR   B9LGS9, NUON_CHLSY ;  Q1QSU4, NUON_CHRSD ;  A8ADW3, NUON_CITK8 ;
DR   A6LXP5, NUON_CLOB8 ;  Q83BR8, NUON_COXBU ;  B3R3Y0, NUON_CUPTR ;
DR   Q11VC5, NUON_CYTH3 ;  Q47HG3, NUON_DECAR ;  A5FQX9, NUON_DEHSB ;
DR   Q9RUA0, NUON_DEIRA ;  B1I6I5, NUON_DESAP ;  B8J1C7, NUON_DESDA ;
DR   B8FRJ7, NUON_DESHD ;  Q6ANN6, NUON_DESPS ;  A4J650, NUON_DESRM ;
DR   A7ZP90, NUON_ECO24 ;  B7UFT4, NUON_ECO27 ;  B7LAT8, NUON_ECO55 ;
DR   P0AFF1, NUON_ECO57 ;  B5YXR6, NUON_ECO5E ;  B7NNV5, NUON_ECO7I ;
DR   B7MXV5, NUON_ECO81 ;  B7M5V5, NUON_ECO8A ;  C4ZUB9, NUON_ECOBW ;
DR   A8A2E5, NUON_ECOHS ;  A1ADC4, NUON_ECOK1 ;  Q0TFH0, NUON_ECOL5 ;
DR   Q8FFK3, NUON_ECOL6 ;  B1IXR6, NUON_ECOLC ;  P0AFF0, NUON_ECOLI ;
DR   B6I7M6, NUON_ECOSE ;  B1LLM9, NUON_ECOSM ;  Q1R9E1, NUON_ECOUT ;
DR   Q3YRZ4, NUON_EHRCJ ;  A4WCQ5, NUON_ENT38 ;  A7MHT8, NUON_ENTS8 ;
DR   Q6D2S9, NUON_ERWCT ;  B2VIN7, NUON_ERWT9 ;  Q2NA79, NUON_ERYLH ;
DR   A5FKK7, NUON_FLAJ1 ;  A6H1Q0, NUON_FLAPJ ;  A8LC88, NUON_FRASN ;
DR   A7NEJ7, NUON_FRATF ;  C1A8Y1, NUON_GEMAT ;  B5E960, NUON_GEOBB ;
DR   Q5KUK6, NUON_GEOKA ;  B3E9V6, NUON_GEOLS ;  Q39ZA5, NUON_GEOMG ;
DR   C5D978, NUON_GEOSW ;  A5GD16, NUON_GEOUR ;  A9HRS3, NUON_GLUDA ;
DR   Q0BSL5, NUON_GRABC ;  A1WXV4, NUON_HALHL ;  C4K3W3, NUON_HAMD5 ;
DR   Q17Z65, NUON_HELAH ;  Q7VFT5, NUON_HELHP ;  B0TH87, NUON_HELMI ;
DR   A4G631, NUON_HERAR ;  C6XJX0, NUON_HIRBI ;  Q0C1D1, NUON_HYPNA ;
DR   Q28T49, NUON_JANSC ;  B5XNW6, NUON_KLEP3 ;  A6TBW2, NUON_KLEP7 ;
DR   C1DCB6, NUON_LARHH ;  Q5WT33, NUON_LEGPL ;  B0SFU5, NUON_LEPBA ;
DR   Q8F7R0, NUON_LEPIN ;  Q2W3J7, NUON_MAGSA ;  A0LDR4, NUON_MAGSM ;
DR   Q0APX7, NUON_MARMM ;  Q608Y9, NUON_METCA ;  B3DZT0, NUON_METI4 ;
DR   B8IUV9, NUON_METNO ;  C6XAK0, NUON_METSD ;  Q2RJT7, NUON_MOOTA ;
DR   B1MAF7, NUON_MYCA9 ;  P0A5M1, NUON_MYCBO ;  A3Q537, NUON_MYCSJ ;
DR   P0A5M0, NUON_MYCTU ;  Q1DDD3, NUON_MYXXD ;  Q5F629, NUON_NEIG1 ;
DR   C6V5H7, NUON_NEORI ;  Q82TV6, NUON_NITEU ;  Q2YA93, NUON_NITMU ;
DR   A1SE40, NUON_NOCSJ ;  B3CUJ6, NUON_ORITI ;  C6D5D2, NUON_PAESJ ;
DR   A1B479, NUON_PARDP ;  A7HY36, NUON_PARL1 ;  Q6MDQ3, NUON_PARUW ;
DR   C6DA34, NUON_PECCP ;  Q3A815, NUON_PELCD ;  A1ALQ2, NUON_PELPD ;
DR   Q4FM78, NUON_PELUB ;  C0QR92, NUON_PERMH ;  Q7N2J9, NUON_PHOLL ;
DR   A1VM73, NUON_POLNA ;  B1XUL1, NUON_POLNS ;  Q6A6H1, NUON_PROAC ;
DR   B4EZ47, NUON_PROMH ;  Q9I0I9, NUON_PSEAE ;  A4XV14, NUON_PSEMY ;
DR   Q4FU52, NUON_PSYA2 ;  Q2K9R9, NUON_RHIEC ;  P50973, NUON_RHOCA ;
DR   B6ISW8, NUON_RHOCS ;  C1AZG0, NUON_RHOOB ;  Q07QW3, NUON_RHOP5 ;
DR   Q2RU27, NUON_RHORT ;  A4WT80, NUON_RHOS5 ;  Q1RIF2, NUON_RICBR ;
DR   Q92HH5, NUON_RICCN ;  Q4UL68, NUON_RICFE ;  Q9ZD13, NUON_RICPR ;
DR   Q68WJ7, NUON_RICTY ;  Q1AVJ2, NUON_RUBXD ;  A1AVS5, NUON_RUTMC ;
DR   A4FPS8, NUON_SACEN ;  B5EZJ7, NUON_SALA4 ;  A8M609, NUON_SALAI ;
DR   A9MJA9, NUON_SALAR ;  Q57M40, NUON_SALCH ;  B5FPF7, NUON_SALDC ;
DR   B5R2Z7, NUON_SALEP ;  B5RCE1, NUON_SALG2 ;  B4TBI2, NUON_SALHS ;
DR   B4SYY7, NUON_SALNS ;  Q5PN71, NUON_SALPA ;  A9N592, NUON_SALPB ;
DR   C0Q051, NUON_SALPC ;  Q2S2K9, NUON_SALRD ;  B4TPJ8, NUON_SALSV ;
DR   Q8Z530, NUON_SALTI ;  A4X1Z0, NUON_SALTO ;  Q8ZNE4, NUON_SALTY ;
DR   A8GH04, NUON_SERP5 ;  B1KJW0, NUON_SHEWM ;  B2TW57, NUON_SHIB3 ;
DR   Q31YI5, NUON_SHIBS ;  Q32DR3, NUON_SHIDS ;  Q83QT2, NUON_SHIFL ;
DR   Q3YZT4, NUON_SHISS ;  Q2NSL1, NUON_SODGM ;  Q1GTL2, NUON_SPHAL ;
DR   A5VAN3, NUON_SPHWW ;  Q30PJ2, NUON_SULDN ;  A6QCE9, NUON_SULNB ;
DR   Q47LF7, NUON_THEFY ;  B9L178, NUON_THERP ;  Q31HE7, NUON_THICR ;
DR   Q3SJP4, NUON_THIDA ;  B8GNZ8, NUON_THISH ;  C4LB43, NUON_TOLAT ;
DR   Q7MA37, NUON_WOLSU ;  Q5GS15, NUON_WOLTR ;  Q3BRP2, NUON_XANC5 ;
DR   A1JLL1, NUON_YERE8 ;  A7FGR6, NUON_YERP3 ;  Q1C6C1, NUON_YERPA ;
DR   B2K809, NUON_YERPB ;  Q7CJ84, NUON_YERPE ;  A9R6K9, NUON_YERPG ;
DR   Q1CHR3, NUON_YERPN ;  A4TM24, NUON_YERPP ;  Q669B2, NUON_YERPS ;
DR   B1JGM5, NUON_YERPY ;
//
ID   1.6.99.6
DE   NADPH dehydrogenase (quinone).
CA   NADPH + acceptor = NADP(+) + reduced acceptor.
CF   Flavoprotein.
CC   -!- Menaquinone can act as acceptor.
CC   -!- Inhibited by dicoumarol and folic acid derivatives but not by 2,4-
CC       dinitrophenol.
//
ID   1.6.99.7
DE   Transferred entry: 1.5.1.34.
//
ID   1.6.99.8
DE   Transferred entry: 1.16.1.3.
//
ID   1.6.99.9
DE   Transferred entry: 1.16.1.4.
//
ID   1.6.99.10
DE   Transferred entry: 1.5.1.34.
//
ID   1.6.99.11
DE   Transferred entry: 1.16.1.5.
//
ID   1.6.99.12
DE   Transferred entry: 1.16.1.6.
//
ID   1.6.99.13
DE   Transferred entry: 1.16.1.7.
//
ID   1.7.1.1
DE   Nitrate reductase (NADH).
AN   Assimilatory NADH:nitrate reductase.
AN   Assimilatory nitrate reductase.
AN   NADH-dependent nitrate reductase.
AN   NADH-nitrate reductase.
AN   NADH:nitrate oxidoreductase.
AN   Nitrate reductase (NADH(2)).
CA   Nitrite + NAD(+) + H(2)O = nitrate + NADH.
CF   FAD or FMN; Heme; Molybdenum.
CC   -!- Formerly EC 1.6.6.1.
PR   PROSITE; PDOC00170;
PR   PROSITE; PDOC00484;
DR   P11832, NIA1_ARATH ;  P39867, NIA1_BRANA ;  P27967, NIA1_HORVU ;
DR   P17571, NIA1_MAIZE ;  P16081, NIA1_ORYSJ ;  P39865, NIA1_PHAVU ;
DR   P54233, NIA1_SOYBN ;  P11605, NIA1_TOBAC ;  P11035, NIA2_ARATH ;
DR   P39868, NIA2_BRANA ;  P27969, NIA2_HORVU ;  P39866, NIA2_PHAVU ;
DR   P39870, NIA2_SOYBN ;  P08509, NIA2_TOBAC ;  P49102, NIA3_MAIZE ;
DR   Q01170, NIA_CHLVU  ;  P43101, NIA_CICIN  ;  P17569, NIA_CUCMA  ;
DR   P39869, NIA_LOTJA  ;  P39882, NIA_LOTTE  ;  P36859, NIA_PETHY  ;
DR   P17570, NIA_SOLLC  ;  P23312, NIA_SPIOL  ;  P36841, NIA_VOLCA  ;
//
ID   1.7.1.2
DE   Nitrate reductase (NAD(P)H).
AN   Assimilatory NAD(P)H-nitrate reductase.
AN   Assimilatory nitrate reductase.
AN   NAD(P)H bispecific nitrate reductase.
AN   NAD(P)H-nitrate reductase.
AN   NAD(P)H:nitrate oxidoreductase.
AN   Nitrate reductase (reduced nicotinamide adenine dinucleotide
AN   (phosphate)).
AN   Nitrate reductase NAD(P)H.
CA   Nitrite + NAD(P)(+) + H(2)O = nitrate + NAD(P)H.
CF   FAD or FMN; Heme; Molybdenum.
CC   -!- Formerly EC 1.6.6.2.
PR   PROSITE; PDOC00170;
PR   PROSITE; PDOC00484;
DR   P39871, NIA2_MAIZE ;  P27968, NIA7_HORVU ;  P27783, NIA_BETPN  ;
//
ID   1.7.1.3
DE   Nitrate reductase (NADPH).
AN   Assimilatory NADPH-nitrate reductase.
AN   Assimilatory nitrate reductase.
AN   Assimilatory reduced nicotinamide adenine dinucleotide phosphate-nitrate
AN   reductase.
AN   NADPH-nitrate reductase.
AN   NADPH:nitrate oxidoreductase.
AN   NADPH:nitrate reductase.
AN   Nitrate reductase (NADPH(2)).
AN   Triphosphopyridine nucleotide-nitrate reductase.
CA   Nitrite + NADP(+) + H(2)O = nitrate + NADPH.
CF   FAD; Heme; Iron-sulfur; Molybdenum.
CC   -!- Formerly EC 1.6.6.3.
PR   PROSITE; PDOC00170;
PR   PROSITE; PDOC00484;
DR   P36858, NIA_ASPNG  ;  P43100, NIA_BEABA  ;  P22945, NIA_EMENI  ;
DR   P39863, NIA_FUSOX  ;  P36842, NIA_LEPMC  ;  P08619, NIA_NEUCR  ;
DR   P39864, NIA_PHYIN  ;  P49050, NIA_PICAN  ;  Q05531, NIA_USTMA  ;
//
ID   1.7.1.4
DE   Nitrite reductase (NAD(P)H).
AN   Assimilatory nitrite reductase.
AN   NAD(P)H:nitrite oxidoreductase.
AN   NADH-nitrite oxidoreductase.
AN   NADPH-nitrite reductase.
AN   Nitrite reductase (reduced nicotinamide adenine dinucleotide
AN   (phosphate)).
CA   Ammonium hydroxide + 3 NAD(P)(+) + H(2)O = nitrite + 3 NAD(P)H.
CF   FAD; Iron; Iron-sulfur; Siroheme.
CC   -!- Formerly EC 1.6.6.4.
DR   P42435, NASD_BACSU ;  P42436, NASE_BACSU ;  P08201, NIRB_ECOLI ;
DR   Q06458, NIRB_KLEOX ;  P0A9I9, NIRD_ECO57 ;  P0A9I8, NIRD_ECOLI ;
DR   P0A230, NIRD_SALTI ;  P0A229, NIRD_SALTY ;  P22944, NIR_EMENI  ;
DR   P43504, NIR_LEPMC  ;  P38681, NIR_NEUCR  ;
//
ID   1.7.1.5
DE   Hyponitrite reductase.
AN   NADH:hyponitrite oxidoreductase.
CA   2 hydroxylamine + 2 NAD(+) = hyponitrous acid + 2 NADH.
CF   Metal ions.
CC   -!- Formerly EC 1.6.6.6.
//
ID   1.7.1.6
DE   Azobenzene reductase.
AN   Azo reductase.
AN   Azo-dye reductase.
AN   Azoreductase.
AN   Dibromopropylaminophenylazobenzoic azoreductase.
AN   Dimethylaminobenzene reductase.
AN   Methyl red azoreductase.
AN   N,N-dimethyl-4-phenylazoaniline azoreductase.
AN   NAD(P)H:1-(4'-sulfophenylazo)-2-naphthol oxidoreductase.
AN   NADPH-dependent azoreductase.
AN   NADPH:4-(dimethylamino)azobenzene oxidoreductase.
AN   NC-reductase.
AN   New coccine (NC)-reductase.
AN   Nicotinamide adenine dinucleotide (phosphate) azoreductase.
AN   Orange I azoreductase.
AN   Orange II azoreductase.
AN   p-aminoazobenzene reductase.
AN   p-dimethylaminoazobenzene azoreductase.
CA   N,N-dimethyl-1,4-phenylenediamine + aniline + 2 NADP(+) =
CA   4-(dimethylamino)azobenzene + 2 NADPH.
CC   -!- The reaction occurs in the reverse direction to that shown above.
CC   -!- Other azo dyes, such as Methyl Red, Rocceline, Solar Orange and
CC       Sumifix Black B can also be reduced.
CC   -!- Formerly EC 1.6.6.7.
DR   Q9FAW5, AZRB_BACOY ;
//
ID   1.7.1.7
DE   GMP reductase.
AN   Guanosine 5'-monophosphate oxidoreductase.
AN   Guanosine 5'-monophosphate reductase.
AN   Guanosine 5'-phosphate reductase.
AN   Guanosine monophosphate reductase.
AN   Guanylate reductase.
AN   NADPH:GMP oxidoreductase (deaminating).
AN   NADPH:guanosine-5'-phosphate oxidoreductase (deaminating).
CA   Inosine 5'-phosphate + NH(3) + NADP(+) = guanosine 5'-phosphate + NADPH.
CC   -!- Formerly EC 1.6.6.8.
PR   PROSITE; PDOC00391;
DR   P36959, GMPR1_HUMAN;  Q9DCZ1, GMPR1_MOUSE;  Q9Z244, GMPR1_RAT  ;
DR   Q32L93, GMPR2_BOVIN;  Q9P2T1, GMPR2_HUMAN;  Q99L27, GMPR2_MOUSE;
DR   P27442, GMPR_ASCSU ;  O16294, GMPR_CAEEL ;  Q9NJD8, GMPR_ONCVO ;
DR   P59075, GMPR_PHYIN ;  A1TNF7, GUAC_ACIAC ;  B9ME75, GUAC_ACIET ;
DR   A1WB23, GUAC_ACISJ ;  A0KN65, GUAC_AERHH ;  A4SJY8, GUAC_AERS4 ;
DR   B6ERC3, GUAC_ALISL ;  A7Z8C3, GUAC_BACA2 ;  A0RLN5, GUAC_BACAH ;
DR   Q81JJ9, GUAC_BACAN ;  Q72WY4, GUAC_BACC1 ;  Q814I1, GUAC_BACCR ;
DR   Q630E8, GUAC_BACCZ ;  Q6HAI0, GUAC_BACHK ;  Q65LF6, GUAC_BACLD ;
DR   Q5WD10, GUAC_BACSK ;  O05269, GUAC_BACSU ;  B8D903, GUAC_BUCA5 ;
DR   P57300, GUAC_BUCAI ;  Q8K9U0, GUAC_BUCAP ;  B8D7A8, GUAC_BUCAT ;
DR   P59443, GUAC_BUCBP ;  Q7NTY1, GUAC_CHRVO ;  A8ALJ2, GUAC_CITK8 ;
DR   Q97DK4, GUAC_CLOAB ;  A9BNR6, GUAC_DELAS ;  A7ZHJ5, GUAC_ECO24 ;
DR   B7UIF3, GUAC_ECO27 ;  B7MAM6, GUAC_ECO45 ;  B7LFX2, GUAC_ECO55 ;
DR   Q8X984, GUAC_ECO57 ;  B5YZD9, GUAC_ECO5E ;  B7NI65, GUAC_ECO7I ;
DR   B7MNW1, GUAC_ECO81 ;  B7M145, GUAC_ECO8A ;  C4ZRJ8, GUAC_ECOBW ;
DR   B1XC80, GUAC_ECODH ;  A7ZW55, GUAC_ECOHS ;  A1A7E7, GUAC_ECOK1 ;
DR   Q0TLN6, GUAC_ECOL5 ;  P60561, GUAC_ECOL6 ;  B1IQN5, GUAC_ECOLC ;
DR   P60560, GUAC_ECOLI ;  B7N7X5, GUAC_ECOLU ;  B6HZ81, GUAC_ECOSE ;
DR   B1LG40, GUAC_ECOSM ;  Q1RG92, GUAC_ECOUT ;  C5B9H0, GUAC_EDWI9 ;
DR   A4W6K6, GUAC_ENT38 ;  Q831S1, GUAC_ENTFA ;  B7LWQ6, GUAC_ESCF3 ;
DR   B1YH73, GUAC_EXIS2 ;  C4L088, GUAC_EXISA ;  B5Z7L6, GUAC_HELPG ;
DR   Q1CT17, GUAC_HELPH ;  Q9ZKZ2, GUAC_HELPJ ;  B2USX4, GUAC_HELPS ;
DR   O25525, GUAC_HELPY ;  B5Y1T3, GUAC_KLEP3 ;  A6T4P6, GUAC_KLEP7 ;
DR   Q5FHY3, GUAC_LACAC ;  Q03TT0, GUAC_LACBA ;  Q03AR1, GUAC_LACC3 ;
DR   B3WCK9, GUAC_LACCB ;  Q1GBV3, GUAC_LACDA ;  Q04CB0, GUAC_LACDB ;
DR   Q045S8, GUAC_LACGA ;  P60565, GUAC_LACJO ;  Q9CGF1, GUAC_LACLA ;
DR   A2RL29, GUAC_LACLM ;  Q02Z38, GUAC_LACLS ;  Q88SV5, GUAC_LACPL ;
DR   Q1WT04, GUAC_LACS1 ;  Q38YF0, GUAC_LACSS ;  B1XWM8, GUAC_LEPCP ;
DR   B1HNS5, GUAC_LYSSC ;  Q6F1U6, GUAC_MESFL ;  Q6MUI1, GUAC_MYCMS ;
DR   Q8ERJ2, GUAC_OCEIH ;  Q04GD9, GUAC_OENOB ;  Q03GJ0, GUAC_PEDPA ;
DR   Q6LGK4, GUAC_PHOPR ;  A1VMA8, GUAC_POLNA ;  Q12CT8, GUAC_POLSJ ;
DR   Q21U05, GUAC_RHOFD ;  B5F7X8, GUAC_SALA4 ;  A9MQA3, GUAC_SALAR ;
DR   Q57TB5, GUAC_SALCH ;  B5FI86, GUAC_SALDC ;  B5R2N9, GUAC_SALEP ;
DR   B5RH79, GUAC_SALG2 ;  B4TJA0, GUAC_SALHS ;  B4SU63, GUAC_SALNS ;
DR   Q5PDH8, GUAC_SALPA ;  A9MZN3, GUAC_SALPB ;  C0Q5K1, GUAC_SALPC ;
DR   B5BLD7, GUAC_SALPK ;  B4TXJ0, GUAC_SALSV ;  Q8Z9F9, GUAC_SALTI ;
DR   Q8ZRT5, GUAC_SALTY ;  A8G9U1, GUAC_SERP5 ;  B0TQE1, GUAC_SHEHH ;
DR   A8HAF6, GUAC_SHEPA ;  B2U2A9, GUAC_SHIB3 ;  Q326D1, GUAC_SHIBS ;
DR   Q32JY8, GUAC_SHIDS ;  Q0T894, GUAC_SHIF8 ;  Q83SM9, GUAC_SHIFL ;
DR   Q3Z5Q5, GUAC_SHISS ;  A7X1Z1, GUAC_STAA1 ;  A6U1F7, GUAC_STAA2 ;
DR   Q2FH96, GUAC_STAA3 ;  Q2FYU4, GUAC_STAA8 ;  A5ISL9, GUAC_STAA9 ;
DR   Q2YXS9, GUAC_STAAB ;  Q5HG83, GUAC_STAAC ;  A6QGN9, GUAC_STAAE ;
DR   P60562, GUAC_STAAM ;  P60563, GUAC_STAAN ;  Q6GH69, GUAC_STAAR ;
DR   Q6G9M1, GUAC_STAAS ;  P60564, GUAC_STAAW ;  B9DP67, GUAC_STACT ;
DR   Q5HPK5, GUAC_STAEQ ;  Q8CPC9, GUAC_STAES ;  Q4L646, GUAC_STAHJ ;
DR   Q49XD2, GUAC_STAS1 ;  Q3K110, GUAC_STRA1 ;  Q8E578, GUAC_STRA3 ;
DR   Q8DZL4, GUAC_STRA5 ;  C0MAM1, GUAC_STRE4 ;  A8AXD6, GUAC_STRGC ;
DR   Q99ZQ1, GUAC_STRP1 ;  Q04K71, GUAC_STRP2 ;  P0DB90, GUAC_STRP3 ;
DR   B5E4Y3, GUAC_STRP4 ;  Q5XC75, GUAC_STRP6 ;  C1C7M7, GUAC_STRP7 ;
DR   Q8P129, GUAC_STRP8 ;  Q1JBS5, GUAC_STRPB ;  Q1JLQ8, GUAC_STRPC ;
DR   Q1JGV8, GUAC_STRPD ;  Q1J6M7, GUAC_STRPF ;  A2REI5, GUAC_STRPG ;
DR   B1IC44, GUAC_STRPI ;  B8ZJR9, GUAC_STRPJ ;  Q48TL6, GUAC_STRPM ;
DR   Q97QG5, GUAC_STRPN ;  P0DB91, GUAC_STRPQ ;  B2IPN4, GUAC_STRPS ;
DR   B5XLI1, GUAC_STRPZ ;  Q8DPJ7, GUAC_STRR6 ;  A4W0T4, GUAC_STRS2 ;
DR   C0MF02, GUAC_STRS7 ;  A4VUJ2, GUAC_STRSY ;  B9DS39, GUAC_STRU0 ;
DR   C1CEK5, GUAC_STRZJ ;  C1CKY8, GUAC_STRZP ;  C1CR55, GUAC_STRZT ;
DR   C4LAB3, GUAC_TOLAT ;  C5CT60, GUAC_VARPS ;  A1WIJ3, GUAC_VEREI ;
DR   A5EYL9, GUAC_VIBC3 ;  Q9KMW9, GUAC_VIBCH ;  C3LUL9, GUAC_VIBCM ;
DR   Q5DZN1, GUAC_VIBF1 ;  B5EUG3, GUAC_VIBFM ;  A7N204, GUAC_VIBHB ;
DR   Q87H06, GUAC_VIBPA ;  B7VS90, GUAC_VIBSL ;  Q8D632, GUAC_VIBVU ;
DR   Q7MD57, GUAC_VIBVY ;  A1JJK8, GUAC_YERE8 ;  A7FM52, GUAC_YERP3 ;
DR   Q1C3T0, GUAC_YERPA ;  B2K4G3, GUAC_YERPB ;  Q8ZBI2, GUAC_YERPE ;
DR   A9R1J4, GUAC_YERPG ;  Q1CLY8, GUAC_YERPN ;  A4TPS6, GUAC_YERPP ;
DR   Q66EJ0, GUAC_YERPS ;  B1JK64, GUAC_YERPY ;
//
ID   1.7.1.8
DE   Deleted entry.
//
ID   1.7.1.9
DE   Nitroquinoline-N-oxide reductase.
AN   4-nitroquinoline 1-oxide reductase.
AN   4NQO reductase.
AN   NAD(P)H:4-nitroquinoline-N-oxide oxidoreductase.
CA   4-(hydroxyamino)quinoline N-oxide + 2 NAD(P)(+) + H(2)O =
CA   4-nitroquinoline N-oxide + 2 NAD(P)H.
CC   -!- Formerly EC 1.6.6.10.
//
ID   1.7.1.10
DE   Hydroxylamine reductase (NADH).
AN   Ammonium dehydrogenase.
AN   Hydroxylamine reductase.
AN   N-hydroxy amine reductase.
AN   NADH-hydroxylamine reductase.
AN   NADH:hydroxylamine oxidoreductase.
CA   NH(3) + NAD(+) + H(2)O = hydroxylamine + NADH.
CC   -!- Also acts on some hydroxamates.
CC   -!- Formerly EC 1.6.6.11.
//
ID   1.7.1.11
DE   4-(dimethylamino)phenylazoxybenzene reductase.
AN   Dimethylaminoazobenzene N-oxide reductase.
AN   N,N-dimethyl-p-aminoazobenzene oxide reductase.
AN   NADPH-dependent DMAB N-oxide reductase.
AN   NADPH:4-(dimethylamino)phenylazoxybenzene oxidoreductase.
CA   4-(dimethylamino)phenylazobenzene + NADP(+) + H(2)O =
CA   4-(dimethylamino)phenylazoxybenzene + NADPH.
CC   -!- Formerly EC 1.6.6.12.
//
ID   1.7.1.12
DE   N-hydroxy-2-acetamidofluorene reductase.
AN   N-hydroxy-2-acetylaminofluorene reductase.
AN   NAD(P)H:N-hydroxy-2-acetamidofluorene N-oxidoreductase.
CA   2-acetamidofluorene + NAD(P)(+) + H(2)O = N-hydroxy-2-acetamidofluorene +
CA   NAD(P)H.
CC   -!- Also acts, more slowly, on N-hydroxy-4-acetamidobiphenyl.
CC   -!- Formerly EC 1.6.6.13.
//
ID   1.7.1.13
DE   PreQ(1) synthase.
AN   7-cyano-7-deazaguanine reductase.
AN   PreQ(0) oxidoreductase.
AN   PreQ(0) reductase.
CA   7-aminomethyl-7-carbaguanine + 2 NADP(+) = 7-cyano-7-carbaguanine +
CA   2 NADPH.
CC   -!- The reaction occurs in the reverse direction.
CC   -!- This enzyme catalyzes one of the early steps in the synthesis of
CC       queosine (Q-tRNA), and is followed by the action of EC 2.4.2.29.
CC   -!- Queosine is found in the wobble position of tRNA(GUN) in eukaryotes
CC       and bacteria and is thought to be involved in translational
CC       modulation.
DR   B0CDX9, QUEF_ACAM1 ;  A1TLC4, QUEF_ACIAC ;  Q6FA61, QUEF_ACIAD ;
DR   B7GZQ9, QUEF_ACIB3 ;  B7I3J1, QUEF_ACIB5 ;  B2HUZ6, QUEF_ACIBC ;
DR   B0VUX1, QUEF_ACIBS ;  A3M741, QUEF_ACIBT ;  B0VBC6, QUEF_ACIBY ;
DR   A5FY70, QUEF_ACICJ ;  B9MDS3, QUEF_ACIET ;  B7J648, QUEF_ACIF2 ;
DR   B5EP57, QUEF_ACIF5 ;  A1WAZ1, QUEF_ACISJ ;  A3N0K4, QUEF_ACTP2 ;
DR   B3H1I1, QUEF_ACTP7 ;  B0BPC7, QUEF_ACTPJ ;  A6VNL8, QUEF_ACTSZ ;
DR   A4SQJ9, QUEF_AERS4 ;  B9J7E0, QUEF_AGRRK ;  Q8UD54, QUEF_AGRT5 ;
DR   B9JZM8, QUEF_AGRVS ;  Q0VR70, QUEF_ALCBS ;  Q0AAV5, QUEF_ALHEH ;
DR   B6EGG7, QUEF_ALISL ;  A6TWD9, QUEF_ALKMQ ;  B8JAR2, QUEF_ANAD2 ;
DR   Q2IH01, QUEF_ANADE ;  A7H750, QUEF_ANADF ;  B4UI08, QUEF_ANASK ;
DR   B9MPS5, QUEF_ANATD ;  Q3M4S2, QUEF_ANAVT ;  O67073, QUEF_AQUAE ;
DR   Q5P6G9, QUEF_AROAE ;  A1KBB9, QUEF_AZOSB ;  C1DRN1, QUEF_AZOVD ;
DR   A7Z3Y9, QUEF_BACA2 ;  C3P4F9, QUEF_BACAA ;  C3LAK7, QUEF_BACAC ;
DR   Q81TC4, QUEF_BACAN ;  B7JFS7, QUEF_BACC0 ;  Q73BF7, QUEF_BACC1 ;
DR   B7IN38, QUEF_BACC2 ;  C1EM52, QUEF_BACC3 ;  B7HH99, QUEF_BACC4 ;
DR   B7HK66, QUEF_BACC7 ;  A7GMN5, QUEF_BACCN ;  B9IUT3, QUEF_BACCQ ;
DR   Q81G66, QUEF_BACCR ;  Q63E28, QUEF_BACCZ ;  Q5LFI5, QUEF_BACFN ;
DR   Q64WA9, QUEF_BACFR ;  Q9KAP6, QUEF_BACHD ;  Q6HLK3, QUEF_BACHK ;
DR   Q65KI3, QUEF_BACLD ;  A8FCI2, QUEF_BACP2 ;  Q5WG44, QUEF_BACSK ;
DR   O31678, QUEF_BACSU ;  Q8A7G0, QUEF_BACTN ;  A9VKS1, QUEF_BACWK ;
DR   Q1LSV9, QUEF_BAUCH ;  Q6MRJ2, QUEF_BDEBA ;  Q2KXN2, QUEF_BORA1 ;
DR   Q7WH69, QUEF_BORBR ;  Q7W9J1, QUEF_BORPA ;  Q7VWV5, QUEF_BORPE ;
DR   Q89KV4, QUEF_BRAJA ;  A5EK14, QUEF_BRASB ;  A4YVC1, QUEF_BRASO ;
DR   B2S630, QUEF_BRUA1 ;  Q2YRW5, QUEF_BRUA2 ;  Q57CV7, QUEF_BRUAB ;
DR   A9M5J8, QUEF_BRUC2 ;  C0RJF0, QUEF_BRUMB ;  Q8YHJ4, QUEF_BRUME ;
DR   A5VQV8, QUEF_BRUO2 ;  B0CGY1, QUEF_BRUSI ;  Q8G0B6, QUEF_BRUSU ;
DR   Q8K9N6, QUEF_BUCAP ;  B1YWG4, QUEF_BURA4 ;  Q1BTM9, QUEF_BURCA ;
DR   B1JYK1, QUEF_BURCC ;  A0KAG0, QUEF_BURCH ;  B4EBB9, QUEF_BURCJ ;
DR   Q0BBX9, QUEF_BURCM ;  A9AFB4, QUEF_BURM1 ;  A3MNT1, QUEF_BURM7 ;
DR   A2S8K4, QUEF_BURM9 ;  Q62MP8, QUEF_BURMA ;  A1V760, QUEF_BURMS ;
DR   A3NRI7, QUEF_BURP0 ;  Q3JW01, QUEF_BURP1 ;  A3N5U2, QUEF_BURP6 ;
DR   B2JCU2, QUEF_BURP8 ;  B2SX29, QUEF_BURPP ;  Q63XA4, QUEF_BURPS ;
DR   Q39D07, QUEF_BURS3 ;  Q2T144, QUEF_BURTA ;  A4JHT1, QUEF_BURVG ;
DR   Q145P6, QUEF_BURXL ;  A8FP38, QUEF_CAMJ8 ;  A7H668, QUEF_CAMJD ;
DR   Q9PLV4, QUEF_CAMJE ;  A1W1X5, QUEF_CAMJJ ;  Q5HS73, QUEF_CAMJR ;
DR   B9KE89, QUEF_CAMLR ;  B8H0X4, QUEF_CAUCN ;  Q9A515, QUEF_CAUCR ;
DR   B0T8W6, QUEF_CAUSK ;  Q3APR5, QUEF_CHLCH ;  B3QM19, QUEF_CHLP8 ;
DR   B3EMR0, QUEF_CHLPB ;  A1BDZ0, QUEF_CHLPD ;  B3QYB6, QUEF_CHLT3 ;
DR   Q9F719, QUEF_CHLTE ;  Q1QXV0, QUEF_CHRSD ;  Q7NRN0, QUEF_CHRVO ;
DR   A8AP02, QUEF_CITK8 ;  Q47YB3, QUEF_COLP3 ;  B6J5I5, QUEF_COXB1 ;
DR   B6J2N7, QUEF_COXB2 ;  A9KEP6, QUEF_COXBN ;  A9NAF9, QUEF_COXBR ;
DR   Q83F02, QUEF_COXBU ;  Q0KEJ5, QUEF_CUPNH ;  Q475Y9, QUEF_CUPPJ ;
DR   B2AGY8, QUEF_CUPTR ;  B7KBA7, QUEF_CYAP7 ;  Q47DJ9, QUEF_DECAR ;
DR   A9BNL9, QUEF_DELAS ;  B8IYG6, QUEF_DESDA ;  Q6ARX8, QUEF_DESPS ;
DR   Q72DG6, QUEF_DESVH ;  A1VF25, QUEF_DESVV ;  A7ZQN7, QUEF_ECO24 ;
DR   B7UHL0, QUEF_ECO27 ;  B7MLB5, QUEF_ECO45 ;  B7LEX4, QUEF_ECO55 ;
DR   Q8X6S9, QUEF_ECO57 ;  B5Z3F9, QUEF_ECO5E ;  B7NVU2, QUEF_ECO7I ;
DR   B7MZ90, QUEF_ECO81 ;  B7LXL0, QUEF_ECO8A ;  C4ZZU9, QUEF_ECOBW ;
DR   B1XDK3, QUEF_ECODH ;  A8A3S9, QUEF_ECOHS ;  A1AEY1, QUEF_ECOK1 ;
DR   Q0TE64, QUEF_ECOL5 ;  Q8FEF7, QUEF_ECOL6 ;  B1IU47, QUEF_ECOLC ;
DR   Q46920, QUEF_ECOLI ;  B7N728, QUEF_ECOLU ;  B6I6J2, QUEF_ECOSE ;
DR   B1LQY7, QUEF_ECOSM ;  Q1R7P8, QUEF_ECOUT ;  B2KDU6, QUEF_ELUMP ;
DR   A7MR08, QUEF_ENTS8 ;  Q6D8F4, QUEF_ERWCT ;  B2VFX1, QUEF_ERWT9 ;
DR   B7LVW9, QUEF_ESCF3 ;  B1YFM9, QUEF_EXIS2 ;  C4L0V1, QUEF_EXISA ;
DR   Q2J7K4, QUEF_FRASC ;  Q5L1B7, QUEF_GEOKA ;  A4ILP0, QUEF_GEOTN ;
DR   Q7NFD3, QUEF_GLOVI ;  Q5FT82, QUEF_GLUOX ;  Q0BVG3, QUEF_GRABC ;
DR   Q7VL22, QUEF_HAEDU ;  Q4QK45, QUEF_HAEI8 ;  A5UBU4, QUEF_HAEIE ;
DR   A5UF26, QUEF_HAEIG ;  P44153, QUEF_HAEIN ;  B8F3V1, QUEF_HAEPS ;
DR   Q0I3L5, QUEF_HAES1 ;  B0UU49, QUEF_HAES2 ;  Q2SDT2, QUEF_HAHCH ;
DR   A1WY83, QUEF_HALHL ;  Q17ZN4, QUEF_HELAH ;  B6JNQ5, QUEF_HELP2 ;
DR   B5Z935, QUEF_HELPG ;  Q1CRL6, QUEF_HELPH ;  Q9ZJJ9, QUEF_HELPJ ;
DR   B2UVF4, QUEF_HELPS ;  O25959, QUEF_HELPY ;  Q0C137, QUEF_HYPNA ;
DR   Q5QW08, QUEF_IDILO ;  B5XV05, QUEF_KLEP3 ;  A6TD67, QUEF_KLEP7 ;
DR   Q5X7D5, QUEF_LEGPA ;  A5IGU1, QUEF_LEGPC ;  Q5WYT2, QUEF_LEGPL ;
DR   Q04RM8, QUEF_LEPBJ ;  Q051Z3, QUEF_LEPBL ;  Q72RB6, QUEF_LEPIC ;
DR   Q8F4F6, QUEF_LEPIN ;  B9EAC6, QUEF_MACCJ ;  Q2W992, QUEF_MAGSA ;
DR   A0LD64, QUEF_MAGSM ;  Q65TN4, QUEF_MANSM ;  Q0AQT4, QUEF_MARMM ;
DR   Q11L79, QUEF_MESSB ;  B7KRB3, QUEF_METC4 ;  Q604U5, QUEF_METCA ;
DR   A9W6G8, QUEF_METEP ;  Q1H1G9, QUEF_METFK ;  B1ZEJ7, QUEF_METPB ;
DR   B8EJT0, QUEF_METSB ;  B0JPS9, QUEF_MICAN ;  Q5F678, QUEF_NEIG1 ;
DR   B4RNP9, QUEF_NEIG2 ;  Q9JSR7, QUEF_NEIMA ;  Q9K161, QUEF_NEIMB ;
DR   A1KVW5, QUEF_NEIMF ;  Q0AE87, QUEF_NITEC ;  Q82SM6, QUEF_NITEU ;
DR   Q1QMJ0, QUEF_NITHX ;  Q2YBC0, QUEF_NITMU ;  Q3JAH8, QUEF_NITOC ;
DR   A6Q0W4, QUEF_NITSB ;  Q3SRK3, QUEF_NITWN ;  Q8YXQ0, QUEF_NOSS1 ;
DR   Q2G586, QUEF_NOVAD ;  Q8EPA3, QUEF_OCEIH ;  A6X0G9, QUEF_OCHA4 ;
DR   A6LIT0, QUEF_PARD8 ;  A1B9Q2, QUEF_PARDP ;  A7HXX4, QUEF_PARL1 ;
DR   Q9CNF6, QUEF_PASMU ;  C6DAH4, QUEF_PECCP ;  Q3B2F0, QUEF_PELLD ;
DR   B4SDY9, QUEF_PELPB ;  Q7N8Q7, QUEF_PHOLL ;  Q6LN10, QUEF_PHOPR ;
DR   A1VS34, QUEF_POLNA ;  Q126D2, QUEF_POLSJ ;  B2RJW0, QUEF_PORG3 ;
DR   Q7MUX8, QUEF_PORGI ;  B4S5H3, QUEF_PROA2 ;  A3PEU9, QUEF_PROM0 ;
DR   A8G6W1, QUEF_PROM2 ;  A2C6W2, QUEF_PROM3 ;  A2BYI6, QUEF_PROM5 ;
DR   Q318T1, QUEF_PROM9 ;  Q7VA53, QUEF_PROMA ;  B4F2E4, QUEF_PROMH ;
DR   Q7V5R6, QUEF_PROMM ;  Q7V027, QUEF_PROMP ;  A2BT35, QUEF_PROMS ;
DR   Q46J47, QUEF_PROMT ;  A4SG19, QUEF_PROVI ;  Q48KI2, QUEF_PSE14 ;
DR   A6V3T3, QUEF_PSEA7 ;  B7UWN0, QUEF_PSEA8 ;  Q02NW3, QUEF_PSEAB ;
DR   Q9I037, QUEF_PSEAE ;  Q1I7F9, QUEF_PSEE4 ;  Q4KF97, QUEF_PSEF5 ;
DR   C3K5H2, QUEF_PSEFS ;  Q3IIT0, QUEF_PSEHT ;  A4XTL9, QUEF_PSEMY ;
DR   A5W6E6, QUEF_PSEP1 ;  Q3K9G4, QUEF_PSEPF ;  B0KH99, QUEF_PSEPG ;
DR   Q88KX9, QUEF_PSEPK ;  B1J615, QUEF_PSEPW ;  Q884I1, QUEF_PSESM ;
DR   Q4ZV71, QUEF_PSEU2 ;  Q4FUL7, QUEF_PSYA2 ;  Q1QDK8, QUEF_PSYCK ;
DR   A1SYB5, QUEF_PSYIN ;  Q1LRI7, QUEF_RALME ;  Q8Y288, QUEF_RALSO ;
DR   B3PV52, QUEF_RHIE6 ;  Q2K5P8, QUEF_RHIEC ;  Q1MDH2, QUEF_RHIL3 ;
DR   Q983K4, QUEF_RHILO ;  B5ZY95, QUEF_RHILW ;  Q92N45, QUEF_RHIME ;
DR   C3MFQ1, QUEF_RHISN ;  Q7UVG9, QUEF_RHOBA ;  Q21VW6, QUEF_RHOFD ;
DR   Q2IWC9, QUEF_RHOP2 ;  Q07NE0, QUEF_RHOP5 ;  Q6N5U5, QUEF_RHOPA ;
DR   Q215A3, QUEF_RHOPB ;  Q136E4, QUEF_RHOPS ;  B3Q6L1, QUEF_RHOPT ;
DR   C3PMB3, QUEF_RICAE ;  A8GM19, QUEF_RICAH ;  A8GUI9, QUEF_RICB8 ;
DR   Q1RGY9, QUEF_RICBR ;  A8EXD9, QUEF_RICCK ;  Q92JG5, QUEF_RICCN ;
DR   Q4UNF0, QUEF_RICFE ;  A8F0H9, QUEF_RICM5 ;  Q9ZE74, QUEF_RICPR ;
DR   B0BW26, QUEF_RICRO ;  A8GQN6, QUEF_RICRS ;  Q68XU6, QUEF_RICTY ;
DR   A1AWC8, QUEF_RUTMC ;  Q21LJ5, QUEF_SACD2 ;  B5F4R2, QUEF_SALA4 ;
DR   A9MSB5, QUEF_SALAR ;  Q57KE9, QUEF_SALCH ;  B5FTX0, QUEF_SALDC ;
DR   B5QWQ2, QUEF_SALEP ;  B5RDU6, QUEF_SALG2 ;  B4TG16, QUEF_SALHS ;
DR   B4T4W1, QUEF_SALNS ;  Q5PEK0, QUEF_SALPA ;  A9N2H7, QUEF_SALPB ;
DR   C0PXF6, QUEF_SALPC ;  B5BF23, QUEF_SALPK ;  B4TUI7, QUEF_SALSV ;
DR   Q8Z437, QUEF_SALTI ;  Q8ZMD3, QUEF_SALTY ;  B8E7T7, QUEF_SHEB2 ;
DR   Q12P28, QUEF_SHEDO ;  Q085G4, QUEF_SHEFN ;  Q8EGJ4, QUEF_SHEON ;
DR   Q0HGT5, QUEF_SHESM ;  Q0HT42, QUEF_SHESR ;  B2TZD9, QUEF_SHIB3 ;
DR   Q31XJ6, QUEF_SHIBS ;  Q32CC4, QUEF_SHIDS ;  Q0T1R0, QUEF_SHIF8 ;
DR   Q83JW9, QUEF_SHIFL ;  Q3YY62, QUEF_SHISS ;  Q5LM10, QUEF_SILPO ;
DR   Q1GEZ0, QUEF_SILST ;  A6UBU5, QUEF_SINMW ;  Q2NRK0, QUEF_SODGM ;
DR   A7WZL5, QUEF_STAA1 ;  A6TZK7, QUEF_STAA2 ;  Q2FIR2, QUEF_STAA3 ;
DR   Q2G081, QUEF_STAA8 ;  A5IQT1, QUEF_STAA9 ;  Q2YSK2, QUEF_STAAB ;
DR   Q5HHU4, QUEF_STAAC ;  A6QF37, QUEF_STAAE ;  Q99VP5, QUEF_STAAM ;
DR   Q7A6T4, QUEF_STAAN ;  Q6GIR3, QUEF_STAAR ;  Q6GBA2, QUEF_STAAS ;
DR   A8Z000, QUEF_STAAT ;  Q7A1H9, QUEF_STAAW ;  Q5HR02, QUEF_STAEQ ;
DR   Q8CTG5, QUEF_STAES ;  Q4L4F1, QUEF_STAHJ ;  Q49VS6, QUEF_STAS1 ;
DR   B4SLB7, QUEF_STRM5 ;  B2FJS1, QUEF_STRMK ;  Q8DUL0, QUEF_STRMU ;
DR   Q97P67, QUEF_STRPN ;  Q8DNP8, QUEF_STRR6 ;  Q5M061, QUEF_STRT1 ;
DR   Q5M4S2, QUEF_STRT2 ;  Q03L13, QUEF_STRTD ;  Q30UP6, QUEF_SULDN ;
DR   A6Q6J0, QUEF_SULNB ;  Q2LTJ0, QUEF_SYNAS ;  Q8GJN6, QUEF_SYNE7 ;
DR   A0LJR4, QUEF_SYNFM ;  Q5MZT0, QUEF_SYNP6 ;  Q7U8Z6, QUEF_SYNPX ;
DR   Q3AZN8, QUEF_SYNS9 ;  Q3AHI8, QUEF_SYNSC ;  Q55978, QUEF_SYNY3 ;
DR   C5BR59, QUEF_TERTT ;  Q8DMA3, QUEF_THEEB ;  Q9WZP8, QUEF_THEMA ;
DR   A5IIZ4, QUEF_THEP1 ;  B0KAC5, QUEF_THEP3 ;  B0K421, QUEF_THEPX ;
DR   B9L0W9, QUEF_THERP ;  B1LCN9, QUEF_THESQ ;  Q8R9P3, QUEF_THETN ;
DR   Q31DJ4, QUEF_THICR ;  Q3SJI1, QUEF_THIDA ;  B8GTL3, QUEF_THISH ;
DR   C4L9Z3, QUEF_TOLAT ;  Q113I7, QUEF_TRIEI ;  A1WS75, QUEF_VEREI ;
DR   A5CWU3, QUEF_VESOH ;  Q9KTK0, QUEF_VIBCH ;  Q5E7A3, QUEF_VIBF1 ;
DR   B5FAU1, QUEF_VIBFM ;  A7MYB6, QUEF_VIBHB ;  Q87RS6, QUEF_VIBPA ;
DR   B7VIV4, QUEF_VIBSL ;  Q8DFB8, QUEF_VIBVU ;  Q7MN30, QUEF_VIBVY ;
DR   Q7MSY1, QUEF_WOLSU ;  Q8PFX6, QUEF_XANAC ;  Q3BNG9, QUEF_XANC5 ;
DR   Q4UPX6, QUEF_XANC8 ;  B0RWU6, QUEF_XANCB ;  Q8P4C5, QUEF_XANCP ;
DR   Q2NYB8, QUEF_XANOM ;  B2SKC6, QUEF_XANOP ;  Q5GV34, QUEF_XANOR ;
DR   B2I6I8, QUEF_XYLF2 ;  Q9PAW2, QUEF_XYLFA ;  B0U3N1, QUEF_XYLFM ;
DR   Q87BP7, QUEF_XYLFT ;  A1JP94, QUEF_YERE8 ;  A7FFG0, QUEF_YERP3 ;
DR   Q1CAP6, QUEF_YERPA ;  B2JZ44, QUEF_YERPB ;  Q8ZH75, QUEF_YERPE ;
DR   A9R2J3, QUEF_YERPG ;  Q1CFD5, QUEF_YERPN ;  A4TLA2, QUEF_YERPP ;
DR   Q667I0, QUEF_YERPS ;  B1JQF1, QUEF_YERPY ;  Q5NQQ4, QUEF_ZYMMO ;
//
ID   1.7.1.14
DE   Nitric oxide reductase (NAD(P), nitrous oxide-forming).
AN   Cytochrome P450nor.
AN   Fungal nitric oxide reductase.
AN   NOR.
CA   Nitrous oxide + NAD(P)(+) + H(2)O = 2 nitric oxide + NAD(P)H.
CF   Heme-thiolate.
CC   -!- The enzyme from Fusarium oxysporum utilizes only NADH, but the
CC       isozyme from Trichosporon cutaneum utilizes both NADH and NADPH.
CC   -!- The electron transfer from NAD(P)H to heme occurs directly,
CC       not requiring flavin or other redox cofactors.
//
ID   1.7.2.1
DE   Nitrite reductase (NO-forming).
AN   cd-cytochrome nitrite reductase.
AN   Cytochrome c-551:O(2), NO(2)(+) oxidoreductase.
AN   Cytochrome cd.
AN   Cytochrome cd1.
AN   Hydroxylamine (acceptor) reductase.
AN   Methyl viologen-nitrite reductase.
AN   Nitrite reductase.
AN   Nitrite reductase (cytochrome).
AN   Nitrite reductase (cytochrome; NO-forming).
AN   Pseudomonas cytochrome oxidase.
CA   Nitric oxide + H(2)O + ferricytochrome c = nitrite + ferrocytochrome c +
CA   2 H(+).
CF   Copper or iron; FAD.
CC   -!- The reaction is catalyzed by two types of enzymes, found in the
CC       perimplasm of denitrifying bacteria.
CC   -!- One type comprises proteins containing multiple copper centers,
CC       the other a heme protein, cytochrome cd1.
CC   -!- Acceptors include c-type cytochromes such as cytochrome c-550 or
CC       cytochrome c-551 from Paracoccus denitrificans or Pseudomonas
CC       aeruginosa, and small blue copper proteins such as azurin and
CC       pseudoazurin.
CC   -!- Cytochrome cd1 also has oxidase and hydroxylamine reductase
CC       activities.
CC   -!- May also catalyze the reaction of EC 1.7.99.1 since this is a well-
CC       known activity of cytochrome cd1.
CC   -!- Formerly EC 1.6.6.5, EC 1.7.99.3 and EC 1.9.3.2.
DR   Q02219, ANIA_NEIGO ;  Q9JTB8, ANIA_NEIMA ;  Q9JYE1, ANIA_NEIMB ;
DR   Q92Z29, NIRK_RHIME ;  Q51700, NIRS_PARDP ;  P72181, NIRS_PARPN ;
DR   P24474, NIRS_PSEAE ;  P24040, NIRS_PSEST ;  P25006, NIR_ACHCY  ;
DR   P38501, NIR_ALCFA  ;  P81445, NIR_ALCXX  ;  Q06006, NIR_PSECL  ;
DR   Q01537, NIR_RHIGA  ;  Q60214, NIR_RHIHE  ;  Q53239, NIR_RHOS5  ;
//
ID   1.7.2.2
DE   Nitrite reductase (cytochrome; ammonia-forming).
AN   Cytochrome c nitrite reductase.
AN   Cytochrome c552.
AN   Multiheme nitrite reductase.
CA   NH(3) + 2 H(2)O + 6 ferricytochrome c = nitrite + 6 ferrocytochrome c +
CA   7 H(+).
CF   Calcium; Heme.
CC   -!- The enzyme also reduces nitric oxide and hydroxylamine to ammonia,
CC       and sulfite to sulfide.
DR   B6EH98, NRFA_ALISL ;  A8ERP8, NRFA_ARCB4 ;  Q5LI95, NRFA_BACFN ;
DR   Q64ZA7, NRFA_BACFR ;  Q8A7V7, NRFA_BACTN ;  A8AN26, NRFA_CITK8 ;
DR   C6BYZ2, NRFA_DESAD ;  Q6ARF1, NRFA_DESPS ;  A7ZUU5, NRFA_ECO24 ;
DR   B7UPN8, NRFA_ECO27 ;  B7MJT8, NRFA_ECO45 ;  B7LB19, NRFA_ECO55 ;
DR   P0ABL0, NRFA_ECO57 ;  B5Z1D1, NRFA_ECO5E ;  B7NSN2, NRFA_ECO7I ;
DR   B7N2T7, NRFA_ECO81 ;  B7M7Y3, NRFA_ECO8A ;  C5A163, NRFA_ECOBW ;
DR   B1XCV6, NRFA_ECODH ;  A8A7H1, NRFA_ECOHS ;  A1AIR1, NRFA_ECOK1 ;
DR   Q0T9X8, NRFA_ECOL5 ;  Q8CVI1, NRFA_ECOL6 ;  B1IUI1, NRFA_ECOLC ;
DR   P0ABK9, NRFA_ECOLI ;  B7NG13, NRFA_ECOLU ;  B6I5T8, NRFA_ECOSE ;
DR   B1LPN5, NRFA_ECOSM ;  Q1R3J6, NRFA_ECOUT ;  C5BES4, NRFA_EDWI9 ;
DR   Q6D613, NRFA_ERWCT ;  Q7VNX8, NRFA_HAEDU ;  Q4QLL8, NRFA_HAEI8 ;
DR   P45017, NRFA_HAEIN ;  Q65RI4, NRFA_MANSM ;  A6L890, NRFA_PARD8 ;
DR   Q06PW6, NRFA_PASHA ;  Q9CPL4, NRFA_PASMU ;  C6DK80, NRFA_PECCP ;
DR   Q6LSQ7, NRFA_PHOPR ;  Q7MTW1, NRFA_PORGI ;  B5F2F2, NRFA_SALA4 ;
DR   A9MGK5, NRFA_SALAR ;  Q57GV0, NRFA_SALCH ;  B5FRF3, NRFA_SALDC ;
DR   B5QZA1, NRFA_SALEP ;  B5R941, NRFA_SALG2 ;  B4TEB5, NRFA_SALHS ;
DR   B4T1X2, NRFA_SALNS ;  Q5PJ02, NRFA_SALPA ;  A9N1R7, NRFA_SALPB ;
DR   C0Q554, NRFA_SALPC ;  B5BJZ8, NRFA_SALPK ;  B4TRK5, NRFA_SALSV ;
DR   Q8Z1Q9, NRFA_SALTI ;  Q8ZKF5, NRFA_SALTY ;  A1S3A0, NRFA_SHEAM ;
DR   Q087T3, NRFA_SHEFN ;  Q8EAC7, NRFA_SHEON ;  A4Y382, NRFA_SHEPC ;
DR   A0KSX7, NRFA_SHESA ;  A8FRR9, NRFA_SHESH ;  Q0HMH8, NRFA_SHESM ;
DR   Q0HRB0, NRFA_SHESR ;  A1RNQ3, NRFA_SHESW ;  B1KFU9, NRFA_SHEWM ;
DR   B2TXA4, NRFA_SHIB3 ;  Q31TS5, NRFA_SHIBS ;  Q83P93, NRFA_SHIFL ;
DR   Q3YUR5, NRFA_SHISS ;  Q9Z4P4, NRFA_SULDE ;  Q5E4J7, NRFA_VIBF1 ;
DR   B5FEY0, NRFA_VIBFM ;  Q87ND9, NRFA_VIBPA ;  Q8D8E5, NRFA_VIBVU ;
DR   Q7MM23, NRFA_VIBVY ;  Q9S1E5, NRFA_WOLSU ;
//
ID   1.7.2.3
DE   Trimethylamine-N-oxide reductase (cytochrome c).
AN   TMAO reductase.
AN   TOR.
CA   Trimethylamine + 2 (ferricytochrome c)-subunit + H(2)O = trimethylamine
CA   N-oxide + 2 (ferrocytochrome c)-subunit + 2 H(+).
CF   Bis(molybdopterin guanine dinucleotide)molybdenum cofactor.
CC   -!- The cytochrome c involved in photosynthetic bacteria is a pentaheme
CC       protein.
CC   -!- The reductant is a membrane-bound multiheme cytochrome c.
CC   -!- Also reduces dimethyl sulfoxide to dimethyl sulfide.
DR   Q52675, DMSA_RHOCA ;  P58360, TORA_ECO57 ;  Q8CW73, TORA_ECOL6 ;
DR   P33225, TORA_ECOLI ;  Q9CK41, TORA_PASMU ;  Q8Z2M4, TORA_SALTI ;
DR   Q8ZKZ7, TORA_SALTY ;  O87948, TORA_SHEMA ;  Q8EHI9, TORA_SHEON ;
DR   Q9KRF0, TORA_VIBCH ;  Q87QI7, TORA_VIBPA ;  Q8D8S3, TORA_VIBVU ;
DR   Q7MLQ2, TORA_VIBVY ;  P58362, TORZ_ECO57 ;  Q8CVZ3, TORZ_ECOL6 ;
DR   P46923, TORZ_ECOLI ;  P44798, TORZ_HAEIN ;
//
ID   1.7.2.4
DE   Nitrous-oxide reductase.
CA   Nitrogen + H(2)O + 2 cytochrome c = nitrous oxide + 2 reduced cytochrome
CA   c.
CF   Copper.
CC   -!- The reaction is observed only in the direction of nitrous oxide
CC       reduction.
CC   -!- Contains the mixed-valent dinuclear CuA species at the electron entry
CC       site of the enzyme, and the tetranuclear Cu-Z center in the active
CC       site.
CC   -!- In Paracoccus pantotrophus, the electron donor is cytochrome c552.
CC   -!- Formerly EC 1.7.99.6.
DR   Q01710, NOSZ2_PSEAE;  P94127, NOSZ_ACHCY ;  Q89XJ6, NOSZ_BRAJA ;
DR   Q8YBC6, NOSZ_BRUME ;  Q8FX16, NOSZ_BRUSU ;  Q59105, NOSZ_CUPNH ;
DR   Q51705, NOSZ_PARDE ;  Q9HYL2, NOSZ_PSEAE ;  Q9F0W4, NOSZ_PSEFL ;
DR   P19573, NOSZ_PSEST ;  Q8XQB8, NOSZ_RALSO ;  Q59746, NOSZ_RHIME ;
//
ID   1.7.2.5
DE   Nitric-oxide reductase (cytochrome c).
CA   Nitrous oxide + 2 ferricytochrome c + H(2)O = 2 nitric oxide +
CA   2 ferrocytochrome c + 2 H(+).
CF   Calcium; Heme; Iron.
CC   -!- The enzyme from Pseudomonas aeruginosa contains a dinuclear center
CC       comprising a non-heme iron center and heme b3, plus heme c, heme b
CC       and calcium; the acceptor is cytochrome c551.
CC   -!- Formerly EC 1.7.99.7.
DR   Q59647, NORB_PSEAE ;  P98008, NORB_PSEST ;
//
ID   1.7.3.1
DE   Nitroalkane oxidase.
AN   NAO.
AN   Nitroethane oxidase.
AN   Nitroethane reductase.
CA   A nitroalkane + H(2)O + O(2) = an aldehyde or ketone + nitrite +
CA   H(2)O(2).
CF   FAD.
CC   -!- While nitroethane may be the physiological substrate, the enzyme also
CC       acts on several other nitroalkanes, including 1-nitropropane,
CC       2-nitropropane, 1-nitrobutane, 1-nitropentane, 1-nitrohexane,
CC       nitrocyclohexane and some nitroalkanols.
CC   -!- Differs from EC 1.13.12.16 in that the preferred substrates are
CC       neutral nitroalkanes rather than anionic nitronates.
//
ID   1.7.3.2
DE   Acetylindoxyl oxidase.
CA   N-acetylindoxyl + O(2) = N-acetylisatin + H(2)O.
//
ID   1.7.3.3
DE   Factor independent urate hydroxylase.
AN   Urate oxidase.
AN   Uric acid oxidase.
AN   Uricase.
AN   Uricase II.
CA   Urate + O(2) + H(2)O = 5-hydroxyisourate + H(2)O(2).
CC   -!- Was previously thought to be a copper protein, but it is now known
CC       that the enzymes from soybean (Glycine max), the mold Aspergillus
CC       flavus and Bacillus subtilis contains no copper nor any other
CC       transition-metal ion.
CC   -!- The 5-hydroxyisourate formed decomposes spontaneously to form
CC       allantoin and CO(2), although there is an enzyme-catalyzed pathway in
CC       which EC 3.5.2.17 catalyzes the first step.
CC   -!- The enzyme is different from EC 1.14.13.113.
PR   PROSITE; PDOC00315;
DR   Q45697, PUCL_BACSB ;  O32141, PUCL_BACSU ;  P34798, URIC1_CANLI;
DR   P04670, URIC1_SOYBN;  P34799, URIC2_CANLI;  O04104, URIC2_SOYBN;
DR   Q8MKJ2, URIC_AOTTR ;  O04420, URIC_ARATH ;  D0VWQ1, URIC_ARTGO ;
DR   Q00511, URIC_ASPFL ;  Q3MHG7, URIC_BOVIN ;  Q5FZI9, URIC_CANFA ;
DR   P78609, URIC_CYBJA ;  Q54LT2, URIC_DICDI ;  P16163, URIC_DROME ;
DR   P22673, URIC_DROPS ;  O44111, URIC_DROSU ;  P23194, URIC_DROVI ;
DR   P33282, URIC_EMENI ;  D8JBB7, URIC_HALJB ;  D4GPU7, URIC_HALVD ;
DR   Q8MHW6, URIC_MACFA ;  Q8MKJ3, URIC_MACMU ;  P25688, URIC_MOUSE ;
DR   P25689, URIC_PAPHA ;  P53763, URIC_PHAVU ;  P16164, URIC_PIG   ;
DR   P82858, URIC_PUCRE ;  P11645, URIC_RABIT ;  P09118, URIC_RAT   ;
DR   O74409, URIC_SCHPO ;
//
ID   1.7.3.4
DE   Hydroxylamine oxidase.
CA   Hydroxylamine + O(2) = nitrite + H(2)O.
CF   Heme.
CC   -!- Hemoprotein with 7 c-type hemes and one P-460-type heme per subunit.
DR   Q50925, HAO_NITEU  ;
//
ID   1.7.3.5
DE   3-aci-nitropropanoate oxidase.
CA   3-aci-nitropropanoate + O(2) = 3-oxopropanoate + nitrite + H(2)O(2).
CF   FMN.
CC   -!- The primary products of the enzymatic reaction are probably the
CC       nitropropanoate free radical and superoxide.
CC   -!- Also acts, more slowly, on 4-aci-nitrobutanoate.
//
ID   1.7.5.1
DE   Nitrate reductase (quinone).
AN   Dissimilatory nitrate reductase.
AN   Nitrate reductase A.
AN   Nitrate reductase Z.
AN   Quinol-nitrate oxidoreductase.
AN   Quinol/nitrate oxidoreductase.
CA   Nitrate + a quinol = nitrite + a quinone + H(2)O.
CF   Heme and molybdopterin guanine dinucleotide and iron-sulfur.
CC   -!- A membrane-bound enzyme which supports anaerobic respiration on
CC       nitrate under anaerobic conditions and in the presence of nitrate
CC       Escherichia coli expresses two forms NarA and NarZ, both being
CC       comprised of three subunits.
PR   PROSITE; PDOC00392;
//
ID   1.7.5.2
DE   Nitric oxide reductase (menaquinol).
CA   2 nitric oxide + menaquinol = nitrous oxide + menaquinone + H(2)O.
CF   Copper.
//
ID   1.7.7.1
DE   Ferredoxin--nitrite reductase.
CA   NH(3) + 2 H(2)O + 6 oxidized ferredoxin = nitrite + 6 reduced ferredoxin
CA   + 7 H(+).
CF   Iron-sulfur; Siroheme.
PR   PROSITE; PDOC00314;
DR   Q39161, NIR_ARATH  ;  P38500, NIR_BETPN  ;  P17847, NIR_MAIZE  ;
DR   Q42997, NIR_ORYSJ  ;  Q51879, NIR_PHOLA  ;  Q43090, NIR_PINSY  ;
DR   P05314, NIR_SPIOL  ;  P39661, NIR_SYNE7  ;
//
ID   1.7.7.2
DE   Ferredoxin--nitrate reductase.
AN   Assimilatory nitrate reductase.
CA   Nitrite + H(2)O + 2 oxidized ferredoxin = nitrate + 2 reduced ferredoxin
CA   + 2 H(+).
CF   Iron-sulfur; Molybdenum.
//
ID   1.7.99.1
DE   Hydroxylamine reductase.
AN   Hydroxylamine (acceptor) reductase.
CA   NH(3) + H(2)O + acceptor = hydroxylamine + reduced acceptor.
CF   Flavoprotein.
CC   -!- Reduced pyocyanine, methylene blue and flavins act as donors for the
CC       reduction of hydroxylamine.
CC   -!- May be identical to EC 1.7.2.1.
DR   Q51700, NIRS_PARDP ;  P72181, NIRS_PARPN ;  P24474, NIRS_PSEAE ;
DR   P24040, NIRS_PSEST ;
//
ID   1.7.99.2
DE   Deleted entry.
//
ID   1.7.99.3
DE   Transferred entry: 1.7.2.1.
//
ID   1.7.99.4
DE   Nitrate reductase.
AN   Respiratory nitrate reductase.
CA   Nitrite + acceptor = nitrate + reduced acceptor.
CC   -!- The Pseudomonas enzyme is a cytochrome, but the enzyme from
CC       Micrococcus halodenitrificans is an iron protein containing
CC       molybdenum.
CC   -!- Reduced benzyl viologen and other dyes bring about the reduction of
CC       nitrate.
PR   PROSITE; PDOC00392;
DR   Q6LTV9, NAPA1_PHOPR;  Q6LQJ3, NAPA2_PHOPR;  A3N277, NAPA_ACTP2 ;
DR   B3H2D1, NAPA_ACTP7 ;  B0BR28, NAPA_ACTPJ ;  A6VQY7, NAPA_ACTSZ ;
DR   A0KIM1, NAPA_AERHH ;  A4SPG7, NAPA_AERS4 ;  Q8VL02, NAPA_AGGAC ;
DR   Q8U7P1, NAPA_AGRT5 ;  Q7WIQ1, NAPA_BORBR ;  Q7W733, NAPA_BORPA ;
DR   A9I7M5, NAPA_BORPD ;  Q89EN5, NAPA_BRAJA ;  A5ED21, NAPA_BRASB ;
DR   A4Z0A1, NAPA_BRASO ;  Q13I15, NAPA_BURXL ;  A7ZCK4, NAPA_CAMC1 ;
DR   A7GZP5, NAPA_CAMC5 ;  A0RQ36, NAPA_CAMFF ;  A7I3Y7, NAPA_CAMHC ;
DR   A8FLJ3, NAPA_CAMJ8 ;  Q9PPD9, NAPA_CAMJE ;  A1VZC8, NAPA_CAMJJ ;
DR   Q5HV12, NAPA_CAMJR ;  B9KCQ2, NAPA_CAMLR ;  A8AE11, NAPA_CITK8 ;
DR   Q487G4, NAPA_COLP3 ;  P39185, NAPA_CUPNH ;  Q46RX3, NAPA_CUPPJ ;
DR   B3R8B4, NAPA_CUPTR ;  Q47A87, NAPA_DECAR ;  P81186, NAPA_DESDA ;
DR   A8LLY9, NAPA_DINSH ;  A7ZP28, NAPA_ECO24 ;  B7UFL9, NAPA_ECO27 ;
DR   B7MFB8, NAPA_ECO45 ;  B7LAM9, NAPA_ECO55 ;  Q8XE47, NAPA_ECO57 ;
DR   B5YWZ7, NAPA_ECO5E ;  B7NN18, NAPA_ECO7I ;  B7MXN6, NAPA_ECO81 ;
DR   B7M5P6, NAPA_ECO8A ;  C4ZU48, NAPA_ECOBW ;  B1X8A2, NAPA_ECODH ;
DR   A8A268, NAPA_ECOHS ;  A1AD59, NAPA_ECOK1 ;  Q0TFN6, NAPA_ECOL5 ;
DR   Q8CVW4, NAPA_ECOL6 ;  B1IY66, NAPA_ECOLC ;  P33937, NAPA_ECOLI ;
DR   B7N5G7, NAPA_ECOLU ;  B6I1A4, NAPA_ECOSE ;  B1LKV2, NAPA_ECOSM ;
DR   Q1R9L3, NAPA_ECOUT ;  C5B7B9, NAPA_EDWI9 ;  Q6D5Z2, NAPA_ERWCT ;
DR   B7LJU7, NAPA_ESCF3 ;  Q7VPJ7, NAPA_HAEDU ;  Q4QNJ6, NAPA_HAEI8 ;
DR   A5UAE1, NAPA_HAEIE ;  B8F7K2, NAPA_HAEPS ;  Q0I5G9, NAPA_HAES1 ;
DR   B0URQ3, NAPA_HAES2 ;  Q2SGV7, NAPA_HAHCH ;  Q7VJT5, NAPA_HELHP ;
DR   C1D9G3, NAPA_LARHH ;  B1Y6A6, NAPA_LEPCP ;  Q93HX3, NAPA_MAGMG ;
DR   Q2W3T1, NAPA_MAGSA ;  Q65Q72, NAPA_MANSM ;  B0UCB6, NAPA_METS4 ;
DR   B9L8L4, NAPA_NAUPA ;  A6Q604, NAPA_NITSB ;  Q56350, NAPA_PARPN ;
DR   Q9CKL8, NAPA_PASMU ;  C6DK59, NAPA_PECCP ;  A6V924, NAPA_PSEA7 ;
DR   B7UX15, NAPA_PSEA8 ;  Q02IZ4, NAPA_PSEAB ;  Q9I4G3, NAPA_PSEAE ;
DR   A4XWM0, NAPA_PSEMY ;  Q3HS05, NAPA_PSEST ;  A4VJ11, NAPA_PSEU5 ;
DR   A1SWQ0, NAPA_PSYIN ;  B2UBL7, NAPA_RALPJ ;  Q92Z36, NAPA_RHIME ;
DR   Q21AR4, NAPA_RHOPB ;  Q53176, NAPA_RHOS4 ;  Q21PN1, NAPA_SACD2 ;
DR   B5EYU5, NAPA_SALA4 ;  A9MJZ6, NAPA_SALAR ;  Q57M92, NAPA_SALCH ;
DR   B5FNQ2, NAPA_SALDC ;  B5R233, NAPA_SALEP ;  B5RC85, NAPA_SALG2 ;
DR   B4TAT3, NAPA_SALHS ;  B4SYT3, NAPA_SALNS ;  Q5PI61, NAPA_SALPA ;
DR   A9N5G2, NAPA_SALPB ;  C0Q0P2, NAPA_SALPC ;  B5BDZ4, NAPA_SALPK ;
DR   B4TPE6, NAPA_SALSV ;  Q8Z570, NAPA_SALTI ;  Q8ZNH6, NAPA_SALTY ;
DR   A8GHJ4, NAPA_SERP5 ;  Q12P44, NAPA_SHEDO ;  B0TSW5, NAPA_SHEHH ;
DR   Q8EIJ1, NAPA_SHEON ;  B2TV30, NAPA_SHIB3 ;  Q31Z29, NAPA_SHIBS ;
DR   Q32I06, NAPA_SHIDS ;  Q0T2R8, NAPA_SHIF8 ;  Q83QV0, NAPA_SHIFL ;
DR   Q3Z001, NAPA_SHISS ;  Q67QZ1, NAPA_SYMTH ;  A5EZX9, NAPA_VIBC3 ;
DR   Q9KLR4, NAPA_VIBCH ;  C3LVU3, NAPA_VIBCM ;  Q5E3J6, NAPA_VIBF1 ;
DR   B5FGW1, NAPA_VIBFM ;  A7N7J3, NAPA_VIBHB ;  Q87GW6, NAPA_VIBPA ;
DR   B7VRL0, NAPA_VIBSL ;  Q8D623, NAPA_VIBVU ;  Q7MD44, NAPA_VIBVY ;
DR   Q7M962, NAPA_WOLSU ;  A1JL26, NAPA_YERE8 ;  A7FG75, NAPA_YERP3 ;
DR   Q1C5S8, NAPA_YERPA ;  B2K970, NAPA_YERPB ;  Q8ZCF3, NAPA_YERPE ;
DR   A9QZL3, NAPA_YERPG ;  Q1CK03, NAPA_YERPN ;  A4TMK8, NAPA_YERPP ;
DR   Q668I0, NAPA_YERPS ;  B1JSJ0, NAPA_YERPY ;  O33732, NARB_SHEFN ;
DR   P39458, NARB_SYNE7 ;  P73448, NARB_SYNY3 ;  P42175, NARG_BACSU ;
DR   P85097, NARG_BRASZ ;  P09152, NARG_ECOLI ;  O06559, NARG_MYCTU ;
DR   P42176, NARH_BACSU ;  P85098, NARH_BRASZ ;  P11349, NARH_ECOLI ;
DR   Q83RN5, NARH_SHIFL ;  P42177, NARI_BACSU ;  P11350, NARI_ECOLI ;
DR   P0AF33, NARV_ECO57 ;  P0AF32, NARV_ECOLI ;  P71994, NARX_MYCTU ;
DR   P19318, NARY_ECOLI ;  P19319, NARZ_ECOLI ;  Q06457, NASA_KLEOX ;
DR   P42434, NASC_BACSU ;
//
ID   1.7.99.5
DE   Transferred entry: 1.5.1.20.
//
ID   1.7.99.6
DE   Transferred entry: 1.7.2.4.
//
ID   1.7.99.7
DE   Transferred entry: 1.7.2.5.
//
ID   1.7.99.8
DE   Hydrazine oxidoreductase.
CA   Hydrazine + acceptor = N(2) + reduced acceptor.
CC   -!- The enzyme is involved in the pathway of anaerobic ammonium oxidation
CC       in anammox bacteria.
CC   -!- The conversion of hydroxylamine by the enzyme from Brocadia
CC       anammoxidans results in the formation of NO and N(2)O.
CC   -!- Hydroxylamine is not a substrate for the enzyme from planctomycete
CC       KSU-1.
//
ID   1.8.1.1
DE   Deleted entry.
//
ID   1.8.1.2
DE   Sulfite reductase (NADPH).
CA   H(2)S + 3 NADP(+) + 3 H(2)O = sulfite + 3 NADPH.
CF   FAD; FMN; Heme.
PR   PROSITE; PDOC00314;
DR   B5XV25, CYSI1_KLEP3;  C6DCZ7, CYSI1_PECCP;  B5Y1B5, CYSI2_KLEP3;
DR   C6DDH3, CYSI2_PECCP;  B7JAM6, CYSI_ACIF2 ;  B5EQW2, CYSI_ACIF5 ;
DR   A3N3D8, CYSI_ACTP2 ;  B3GZ95, CYSI_ACTP7 ;  B0BT17, CYSI_ACTPJ ;
DR   Q8VSR0, CYSI_ACTPL ;  A6VPZ1, CYSI_ACTSZ ;  A0KNL0, CYSI_AERHH ;
DR   B6ELM5, CYSI_ALISL ;  B4RYS6, CYSI_ALTMD ;  B7GJU8, CYSI_ANOFW ;
DR   A7Z8R5, CYSI_BACA2 ;  Q9KF75, CYSI_BACHD ;  Q65L57, CYSI_BACLD ;
DR   A8FDY3, CYSI_BACP2 ;  Q5WKE7, CYSI_BACSK ;  O32213, CYSI_BACSU ;
DR   Q1LTP2, CYSI_BAUCH ;  Q7VQH1, CYSI_BLOFL ;  Q493N3, CYSI_BLOPB ;
DR   A9IT77, CYSI_BORPD ;  C0Z9X2, CYSI_BREBN ;  B8D9K5, CYSI_BUCA5 ;
DR   P57502, CYSI_BUCAI ;  P0C0B2, CYSI_BUCAP ;  B8D7V7, CYSI_BUCAT ;
DR   Q1QU16, CYSI_CHRSD ;  A8ANX0, CYSI_CITK8 ;  Q47UW8, CYSI_COLP3 ;
DR   C6CAW9, CYSI_DICDC ;  C6CLS0, CYSI_DICZE ;  A7ZQK6, CYSI_ECO24 ;
DR   B7UHH5, CYSI_ECO27 ;  B7MKN0, CYSI_ECO45 ;  B7LEI2, CYSI_ECO55 ;
DR   Q8X7U2, CYSI_ECO57 ;  B5Z3C6, CYSI_ECO5E ;  B7NTA0, CYSI_ECO7I ;
DR   B7MYR1, CYSI_ECO81 ;  B7LXH6, CYSI_ECO8A ;  C5W865, CYSI_ECOBD ;
DR   C6UCN7, CYSI_ECOBR ;  C4ZZR7, CYSI_ECOBW ;  A8A3P4, CYSI_ECOHS ;
DR   A1AEU9, CYSI_ECOK1 ;  Q0TEA3, CYSI_ECOL5 ;  Q8FEI8, CYSI_ECOL6 ;
DR   B1IU78, CYSI_ECOLC ;  P17846, CYSI_ECOLI ;  B7N6Z7, CYSI_ECOLU ;
DR   B6I6F7, CYSI_ECOSE ;  B1LQ86, CYSI_ECOSM ;  Q1R7T5, CYSI_ECOUT ;
DR   A4WDW0, CYSI_ENT38 ;  A7MJ64, CYSI_ENTS8 ;  Q6D1A2, CYSI_ERWCT ;
DR   B2VG06, CYSI_ERWT9 ;  B7LWN9, CYSI_ESCF3 ;  Q5L041, CYSI_GEOKA ;
DR   A4IMT6, CYSI_GEOTN ;  A6TD48, CYSI_KLEP7 ;  B0SF75, CYSI_LEPBA ;
DR   B0SNL6, CYSI_LEPBP ;  B1HXC1, CYSI_LYSSC ;  Q65T54, CYSI_MANSM ;
DR   B7L0Y4, CYSI_METC4 ;  C5APZ1, CYSI_METEA ;  A9W4X6, CYSI_METEP ;
DR   B8IRY2, CYSI_METNO ;  B1Z7C5, CYSI_METPB ;  B1LS97, CYSI_METRJ ;
DR   B0U8Y9, CYSI_METS4 ;  B8EKI5, CYSI_METSB ;  Q1D9W9, CYSI_MYXXD ;
DR   A9LZ72, CYSI_NEIM0 ;  Q9JUD9, CYSI_NEIMA ;  Q9JS33, CYSI_NEIMB ;
DR   A1KU05, CYSI_NEIMF ;  Q0AGU3, CYSI_NITEC ;  Q82W45, CYSI_NITEU ;
DR   Q1QQC7, CYSI_NITHX ;  Q3JBJ1, CYSI_NITOC ;  Q3SV33, CYSI_NITWN ;
DR   Q8EQP0, CYSI_OCEIH ;  B6JCW3, CYSI_OLICO ;  C6CXN6, CYSI_PAESJ ;
DR   Q7N8L5, CYSI_PHOLL ;  Q6LM59, CYSI_PHOPR ;  B4F234, CYSI_PROMH ;
DR   Q15NK1, CYSI_PSEA6 ;  Q3IFM1, CYSI_PSEHT ;  A1T054, CYSI_PSYIN ;
DR   B5F430, CYSI_SALA4 ;  A9MF17, CYSI_SALAR ;  Q57KH8, CYSI_SALCH ;
DR   B5FTU2, CYSI_SALDC ;  B5QW35, CYSI_SALEP ;  B5RDS0, CYSI_SALG2 ;
DR   B4TFY4, CYSI_SALHS ;  B4T474, CYSI_SALNS ;  Q5PEH8, CYSI_SALPA ;
DR   A9N2E5, CYSI_SALPB ;  C0PXC5, CYSI_SALPC ;  B5BEZ8, CYSI_SALPK ;
DR   B4TTX8, CYSI_SALSV ;  Q8Z459, CYSI_SALTI ;  P17845, CYSI_SALTY ;
DR   A8G9X7, CYSI_SERP5 ;  A1S9I4, CYSI_SHEAM ;  B8EE51, CYSI_SHEB2 ;
DR   A3D829, CYSI_SHEB5 ;  A6WJT5, CYSI_SHEB8 ;  A9L2P8, CYSI_SHEB9 ;
DR   Q12QQ5, CYSI_SHEDO ;  Q07Y86, CYSI_SHEFN ;  B0TTE4, CYSI_SHEHH ;
DR   A3QAP0, CYSI_SHELP ;  Q8EB00, CYSI_SHEON ;  A8H094, CYSI_SHEPA ;
DR   A4Y9Z3, CYSI_SHEPC ;  B8CJV9, CYSI_SHEPW ;  A0KTH5, CYSI_SHESA ;
DR   A8FZY7, CYSI_SHESH ;  Q0HFL7, CYSI_SHESM ;  Q0HYB3, CYSI_SHESR ;
DR   A1RGD7, CYSI_SHESW ;  B1KE86, CYSI_SHEWM ;  B2TZH1, CYSI_SHIB3 ;
DR   Q31XM5, CYSI_SHIBS ;  Q32CG4, CYSI_SHIDS ;  Q0T1I7, CYSI_SHIF8 ;
DR   Q83QE0, CYSI_SHIFL ;  Q3YY95, CYSI_SHISS ;  Q2NVN3, CYSI_SODGM ;
DR   B9DLM4, CYSI_STACT ;  Q5HKZ7, CYSI_STAEQ ;  Q8CMX5, CYSI_STAES ;
DR   Q4L9F1, CYSI_STAHJ ;  Q49UL9, CYSI_STAS1 ;  P52673, CYSI_THIRO ;
DR   C4L9J8, CYSI_TOLAT ;  A5F3I5, CYSI_VIBC3 ;  Q9KUX3, CYSI_VIBCH ;
DR   C3LRB7, CYSI_VIBCM ;  Q5E840, CYSI_VIBF1 ;  B5FGI9, CYSI_VIBFM ;
DR   A7MSZ7, CYSI_VIBHB ;  Q87L91, CYSI_VIBPA ;  B7VI85, CYSI_VIBSL ;
DR   Q8DCK1, CYSI_VIBVU ;  Q7MHA6, CYSI_VIBVY ;  Q8PHC8, CYSI_XANAC ;
DR   Q3BPY4, CYSI_XANC5 ;  Q4UY08, CYSI_XANC8 ;  B0RPG6, CYSI_XANCB ;
DR   Q8P608, CYSI_XANCP ;  Q2P0H2, CYSI_XANOM ;  B2SI05, CYSI_XANOP ;
DR   Q8KQT8, CYSI_XANOR ;  B2IA31, CYSI_XYLF2 ;  Q9PD81, CYSI_XYLFA ;
DR   B0U6W0, CYSI_XYLFM ;  Q87DH0, CYSI_XYLFT ;  A1JJS3, CYSI_YERE8 ;
DR   A7FLY9, CYSI_YERP3 ;  Q1C3Z1, CYSI_YERPA ;  B2K566, CYSI_YERPB ;
DR   Q8ZBN7, CYSI_YERPE ;  Q1CLS7, CYSI_YERPN ;  A4TPY6, CYSI_YERPP ;
DR   Q66ED3, CYSI_YERPS ;  B1JK04, CYSI_YERPY ;  Q5NRM2, CYSI_ZYMMO ;
DR   O32214, CYSJ_BACSU ;  Q1LTP1, CYSJ_BAUCH ;  Q7VQH2, CYSJ_BLOFL ;
DR   P57503, CYSJ_BUCAI ;  Q8K9D3, CYSJ_BUCAP ;  A8ANX1, CYSJ_CITK8 ;
DR   A7ZQK7, CYSJ_ECO24 ;  Q8X7U1, CYSJ_ECO57 ;  A8A3P5, CYSJ_ECOHS ;
DR   A1AEV0, CYSJ_ECOK1 ;  Q0TEA2, CYSJ_ECOL5 ;  Q8FEI7, CYSJ_ECOL6 ;
DR   B1IU77, CYSJ_ECOLC ;  P38038, CYSJ_ECOLI ;  Q1R7T4, CYSJ_ECOUT ;
DR   A4WDW1, CYSJ_ENT38 ;  A7MJ63, CYSJ_ENTS8 ;  Q6D1A1, CYSJ_ERWCT ;
DR   A6TD49, CYSJ_KLEP7 ;  Q65T53, CYSJ_MANSM ;  A9LZ73, CYSJ_NEIM0 ;
DR   Q9JUD8, CYSJ_NEIMA ;  Q9JS45, CYSJ_NEIMB ;  A1KU06, CYSJ_NEIMF ;
DR   Q7N8L6, CYSJ_PHOLL ;  Q6LM58, CYSJ_PHOPR ;  A9MF16, CYSJ_SALAR ;
DR   Q57KH7, CYSJ_SALCH ;  Q5PEH7, CYSJ_SALPA ;  A9N2E6, CYSJ_SALPB ;
DR   Q8Z458, CYSJ_SALTI ;  P38039, CYSJ_SALTY ;  A8G9X6, CYSJ_SERP5 ;
DR   Q8EAZ9, CYSJ_SHEON ;  A0KTH4, CYSJ_SHESA ;  Q0HFL6, CYSJ_SHESM ;
DR   Q0HYB4, CYSJ_SHESR ;  Q31XM4, CYSJ_SHIBS ;  Q32CG3, CYSJ_SHIDS ;
DR   Q0T1I8, CYSJ_SHIF8 ;  Q83QD9, CYSJ_SHIFL ;  Q3YY94, CYSJ_SHISS ;
DR   Q2NVN4, CYSJ_SODGM ;  P52674, CYSJ_THIRO ;  A5F3I4, CYSJ_VIBC3 ;
DR   Q9KUX4, CYSJ_VIBCH ;  Q5E841, CYSJ_VIBF1 ;  Q87L90, CYSJ_VIBPA ;
DR   Q8DCK2, CYSJ_VIBVU ;  Q7MHA5, CYSJ_VIBVY ;  A1JJS2, CYSJ_YERE8 ;
DR   A7FLZ0, CYSJ_YERP3 ;  Q1C3Z0, CYSJ_YERPA ;  Q8ZBN6, CYSJ_YERPE ;
DR   Q1CLS8, CYSJ_YERPN ;  A4TPY5, CYSJ_YERPP ;  Q66ED4, CYSJ_YERPS ;
DR   Q5NRM1, CYSJ_ZYMMO ;  P47169, ECM17_YEAST;  Q09878, MET10_SCHPO;
DR   P39692, MET10_YEAST;  Q1K9C2, MET5_SCHPO ;
//
ID   1.8.1.3
DE   Hypotaurine dehydrogenase.
CA   Hypotaurine + H(2)O + NAD(+) = taurine + NADH.
CF   Heme; Molybdenum.
//
ID   1.8.1.4
DE   Dihydrolipoyl dehydrogenase.
AN   Dehydrolipoate dehydrogenase.
AN   Diaphorase.
AN   Dihydrolipoamide dehydrogenase.
AN   Dihydrolipoic dehydrogenase.
AN   Dihydrothioctic dehydrogenase.
AN   E3 component of alpha-ketoacid dehydrogenase complexes.
AN   Glycine-cleavage system L-protein.
AN   L-protein.
AN   LDP-Glc.
AN   LDP-Val.
AN   Lipoamide dehydrogenase (NADH).
AN   Lipoamide oxidoreductase (NADH).
AN   Lipoamide reductase.
AN   Lipoamide reductase (NADH).
AN   Lipoate dehydrogenase.
AN   Lipoic acid dehydrogenase.
AN   Lipoyl dehydrogenase.
CA   Protein N(6)-(dihydrolipoyl)lysine + NAD(+) = protein N(6)-(lipoyl)lysine
CA   + NADH.
CF   FAD.
CC   -!- A component of the multienzyme 2-oxo-acid dehydrogenase complexes.
CC   -!- In the pyruvate dehydrogenase complex, it binds to the core of
CC       EC 2.3.1.12 and catalyzes oxidation of its dihydrolipoyl groups.
CC   -!- It plays a similar role in the oxoglutarate and 3-methyl-2-
CC       oxobutanoate dehydrogenase complexes.
CC   -!- Another substrate is the dihydrolipoyl group in the H-protein of the
CC       glycine-cleavage system, in which it acts, together with EC 1.4.4.2
CC       and EC 2.1.2.10 to break down glycine.
CC   -!- It can also use free dihydrolipoate, dihydrolipoamide or
CC       dihydrolipoyllysine as substrate.
CC   -!- Was first shown to catalyze the oxidation of NADH by methylene blue;
CC       this activity was called diaphorase.
CC   -!- The glycine cleavage system is composed of four components that only
CC       loosely associate: the P protein (EC 1.4.4.2), the T protein
CC       (EC 2.1.2.10), the L protein (EC 1.8.1.4) and the lipoyl-bearing H
CC       protein.
CC   -!- Formerly EC 1.6.4.3.
PR   PROSITE; PDOC00073;
DR   Q9M5K3, DLDH1_ARATH;  P21880, DLDH1_BACSU;  P11959, DLDH1_GEOSE;
DR   Q9I1L9, DLDH1_PSEAE;  P09063, DLDH1_PSEPU;  Q9M5K2, DLDH2_ARATH;
DR   P54533, DLDH2_BACSU;  Q5UYG6, DLDH2_HALMA;  Q9I3D1, DLDH2_PSEAE;
DR   P31052, DLDH2_PSEPU;  O34324, DLDH3_BACSU;  Q5UWH2, DLDH3_HALMA;
DR   Q9HUY1, DLDH3_PSEAE;  P31046, DLDH3_PSEPU;  P35484, DLDH_ACHLA ;
DR   P18925, DLDH_AZOVI ;  P57303, DLDH_BUCAI ;  Q8K9T7, DLDH_BUCAP ;
DR   Q89AQ8, DLDH_BUCBP ;  P49819, DLDH_CANFA ;  Q9PJI3, DLDH_CHLMU ;
DR   O50311, DLDH_CHLP8 ;  Q9Z773, DLDH_CHLPN ;  Q8KCW2, DLDH_CHLTE ;
DR   O84561, DLDH_CHLTR ;  Q8CIZ7, DLDH_CRIGR ;  P52992, DLDH_CUPNH ;
DR   Q54EW8, DLDH_DICDI ;  P0A9P2, DLDH_ECO57 ;  P0A9P1, DLDH_ECOL6 ;
DR   P0A9P0, DLDH_ECOLI ;  P43784, DLDH_HAEIN ;  Q9HN74, DLDH_HALSA ;
DR   Q04829, DLDH_HALVD ;  P09622, DLDH_HUMAN ;  P80647, DLDH_HYMDI ;
DR   Q60HG3, DLDH_MACFA ;  O18480, DLDH_MANSE ;  Q811C4, DLDH_MESAU ;
DR   O08749, DLDH_MOUSE ;  P66005, DLDH_MYCBO ;  P47513, DLDH_MYCGE ;
DR   Q50068, DLDH_MYCLE ;  P75393, DLDH_MYCPN ;  P66004, DLDH_MYCTU ;
DR   P31023, DLDH_PEA   ;  P09623, DLDH_PIG   ;  Q5R4B1, DLDH_PONAB ;
DR   P84545, DLDH_POPEU ;  P14218, DLDH_PSEFL ;  Q6P6R2, DLDH_RAT   ;
DR   O05940, DLDH_RHIEC ;  P95596, DLDH_RHOCA ;  O00087, DLDH_SCHPO ;
DR   P0A9P3, DLDH_SHIFL ;  P80503, DLDH_SOLTU ;  Q5HGY8, DLDH_STAAC ;
DR   P0A0E6, DLDH_STAAM ;  P99084, DLDH_STAAN ;  Q6GHY9, DLDH_STAAR ;
DR   Q6GAB8, DLDH_STAAS ;  P0A0E8, DLDH_STAAU ;  P0A0E7, DLDH_STAAW ;
DR   P72740, DLDH_SYNY3 ;  P85207, DLDH_THESS ;  Q04933, DLDH_TRYBB ;
DR   P90597, DLDH_TRYCR ;  Q9KPF6, DLDH_VIBCH ;  O50286, DLDH_VIBPA ;
DR   P09624, DLDH_YEAST ;  P50970, DLDH_ZYMMO ;
//
ID   1.8.1.5
DE   2-oxopropyl-CoM reductase (carboxylating).
AN   2-KPCC.
AN   NADPH:2-(2-ketopropylthio)ethanesulfonate oxidoreductase/carboxylase.
AN   NADPH:2-ketopropyl-coenzyme M oxidoreductase/carboxylase.
CA   2-mercaptoethanesulfonate + acetoacetate + NADP(+) =
CA   2-(2-oxopropylthio)ethanesulfonate + CO(2) + NADPH.
CC   -!- Also acts on thioethers longer in chain length on the oxo side, e.g.
CC       2-oxobutyl-CoM, but this portion must be attached to CoM
CC       (2-mercaptoethanesulfonate); no CoM analogs will substitute.
CC   -!- Forms component II of a four-component enzyme system (comprising
CC       EC 4.4.1.23 (component I), EC 1.8.1.5 (component II), EC 1.1.1.268
CC       (component III) and EC 1.1.1.269 (component IV)) that is involved in
CC       epoxyalkane carboxylation in Xanthobacter sp. strain Py2.
DR   Q56839, XECC_XANP2 ;
//
ID   1.8.1.6
DE   Cystine reductase.
AN   Cystine reductase (NADH).
AN   NADH-dependent cystine reductase.
AN   NADH:L-cystine oxidoreductase.
CA   2 L-cysteine + NAD(+) = L-cystine + NADH.
CC   -!- Formerly EC 1.6.4.1.
//
ID   1.8.1.7
DE   Glutathione-disulfide reductase.
AN   Glutathione reductase.
AN   Glutathione reductase (NADPH).
AN   Glutathione S-reductase.
AN   GSH reductase.
AN   GSSG reductase.
AN   NADPH-glutathione reductase.
AN   NADPH-GSSG reductase.
AN   NADPH:oxidized-glutathione oxidoreductase.
CA   2 glutathione + NADP(+) = glutathione disulfide + NADPH.
CF   FAD.
CC   -!- Activity is dependent on a redox-active disulfide in each of the
CC       active centers.
CC   -!- Formerly EC 1.6.4.2.
PR   PROSITE; PDOC00073;
DR   P48641, GSHRC_ARATH;  O04955, GSHRC_BRARP;  P48642, GSHRC_ORYSJ;
DR   Q43621, GSHRC_PEA  ;  P42770, GSHRP_ARATH;  P27456, GSHRP_PEA  ;
DR   P48640, GSHRP_SOYBN;  Q43154, GSHRP_SPIOL;  P80461, GSHRP_TOBAC;
DR   Q74ZK4, GSHR_ASHGO ;  P48639, GSHR_BURCE ;  P30635, GSHR_CAEEL ;
DR   A2TIL1, GSHR_CALJA ;  Q6FRV2, GSHR_CANGA ;  Q6BPI1, GSHR_DEBHA ;
DR   Q8T137, GSHR_DICDI ;  P06715, GSHR_ECOLI ;  P43783, GSHR_HAEIN ;
DR   P00390, GSHR_HUMAN ;  Q6HA23, GSHR_KLULA ;  P47791, GSHR_MOUSE ;
DR   Q873E8, GSHR_NEUCR ;  P48638, GSHR_NOSS1 ;  O15770, GSHR_PLAF7 ;
DR   Q94655, GSHR_PLAFK ;  P23189, GSHR_PSEAE ;  P70619, GSHR_RAT   ;
DR   P78965, GSHR_SCHPO ;  P11804, GSHR_SPISP ;  Q60151, GSHR_STRTR ;
DR   Q6C5H4, GSHR_YARLI ;  P41921, GSHR_YEAST ;
//
ID   1.8.1.8
DE   Protein-disulfide reductase.
AN   Disulfide reductase.
AN   Insulin-glutathione transhydrogenase.
AN   NAD(P)H:protein-disulfide oxidoreductase.
AN   Protein disulfide reductase.
CA   Protein dithiol + NAD(P)(+) = protein disulfide + NAD(P)H.
CC   -!- Formerly EC 1.6.4.4.
DR   Q9HUW5, DSBD1_PSEAE;  Q9I104, DSBD2_PSEAE;  A3N207, DSBD_ACTP2 ;
DR   Q9PHR3, DSBD_CAMJE ;  Q5HVG7, DSBD_CAMJR ;  A8AMR4, DSBD_CITK8 ;
DR   Q487R3, DSBD_COLP3 ;  P58162, DSBD_ECO57 ;  Q0T9Q5, DSBD_ECOL5 ;
DR   Q8CVH5, DSBD_ECOL6 ;  P36655, DSBD_ECOLI ;  Q1R3C4, DSBD_ECOUT ;
DR   A7MMC7, DSBD_ENTS8 ;  Q6D9J6, DSBD_ERWCT ;  Q7VMZ4, DSBD_HAEDU ;
DR   Q4QM23, DSBD_HAEI8 ;  A5UDI9, DSBD_HAEIE ;  A5UI29, DSBD_HAEIG ;
DR   P44919, DSBD_HAEIN ;  Q5QVU3, DSBD_IDILO ;  A6TH46, DSBD_KLEP7 ;
DR   Q9JTL9, DSBD_NEIMA ;  Q9JYM0, DSBD_NEIMB ;  Q9XDB2, DSBD_PANCI ;
DR   Q9CP40, DSBD_PASMU ;  Q7MZX2, DSBD_PHOLL ;  Q15ZS2, DSBD_PSEA6 ;
DR   Q4K909, DSBD_PSEF5 ;  Q9KJZ3, DSBD_PSEUK ;  Q8XV41, DSBD_RALSO ;
DR   Q57GQ5, DSBD_SALCH ;  Q5PIQ0, DSBD_SALPA ;  Q8Z1A8, DSBD_SALTI ;
DR   Q8ZKC3, DSBD_SALTY ;  Q31T72, DSBD_SHIBS ;  Q328D2, DSBD_SHIDS ;
DR   Q0SXE3, DSBD_SHIF8 ;  Q3YUK4, DSBD_SHISS ;  Q2NW99, DSBD_SODGM ;
DR   Q9KNN1, DSBD_VIBCH ;  Q87KW0, DSBD_VIBPA ;  Q8DCZ0, DSBD_VIBVU ;
DR   Q7MGV6, DSBD_VIBVY ;  A1JIN7, DSBD_YERE8 ;  Q1C0X4, DSBD_YERPA ;
DR   Q8ZIY9, DSBD_YERPE ;  Q1CEC8, DSBD_YERPN ;  A4TRR6, DSBD_YERPP ;
DR   Q66FE1, DSBD_YERPS ;  Q7Y0E8, NRX11_ORYSJ;  Q7Y0F2, NRX12_ORYSJ;
DR   O80763, NRX1_ARATH ;  Q0JIL1, NRX2_ORYSJ ;  Q8VZQ0, NRX3_ARATH ;
DR   Q7XPE8, NRX3_ORYSJ ;  A6QLU8, NXN_BOVIN  ;  Q503L9, NXN_DANRE  ;
DR   Q6DKJ4, NXN_HUMAN  ;  P97346, NXN_MOUSE  ;  Q6GM16, NXN_XENLA  ;
DR   P0AGG6, THIO2_ECO57;  P0AGG5, THIO2_ECOL6;  P0AGG4, THIO2_ECOLI;
DR   P0AGG7, THIO2_SHIFL;
//
ID   1.8.1.9
DE   Thioredoxin-disulfide reductase.
AN   NADP--thioredoxin reductase.
AN   NADPH--thioredoxin reductase.
AN   NADPH:oxidized thioredoxin oxidoreductase.
AN   Thioredoxin reductase (NADPH).
CA   Thioredoxin + NADP(+) = thioredoxin disulfide + NADPH.
CC   -!- May be identical to EC 1.8.1.10.
CC   -!- Formerly EC 1.6.4.5.
PR   PROSITE; PDOC00496;
DR   Q69PS6, NTRA_ORYSJ ;  Q6ZFU6, NTRB_ORYSJ ;  Q70G58, NTRC_ORYSJ ;
DR   Q39243, TRXB1_ARATH;  P29509, TRXB1_YEAST;  Q39242, TRXB2_ARATH;
DR   P38816, TRXB2_YEAST;  O22229, TRXB3_ARATH;  O66790, TRXB_AQUAE ;
DR   Q75CM8, TRXB_ASHGO ;  P80880, TRXB_BACSU ;  P94284, TRXB_BORBU ;
DR   P57399, TRXB_BUCAI ;  P81433, TRXB_BUCAP ;  Q89AJ2, TRXB_BUCBP ;
DR   Q6FR39, TRXB_CANGA ;  Q9PKT7, TRXB_CHLMU ;  Q9Z8M4, TRXB_CHLPN ;
DR   O84101, TRXB_CHLTR ;  P52213, TRXB_CLOLI ;  P39916, TRXB_COXBU ;
DR   Q6BIS1, TRXB_DEBHA ;  Q54UU8, TRXB_DICDI ;  P0A9P5, TRXB_ECO57 ;
DR   P0A9P4, TRXB_ECOLI ;  P50971, TRXB_EUBAC ;  P43788, TRXB_HAEIN ;
DR   Q9ZL18, TRXB_HELPJ ;  P56431, TRXB_HELPY ;  Q6HA24, TRXB_KLULA ;
DR   Q928B5, TRXB_LISIN ;  O32823, TRXB_LISMO ;  Q58931, TRXB_METJA ;
DR   P47348, TRXB_MYCGE ;  P46843, TRXB_MYCLE ;  P75531, TRXB_MYCPN ;
DR   Q98PK9, TRXB_MYCPU ;  O30973, TRXB_MYCSM ;  P52214, TRXB_MYCTU ;
DR   P51978, TRXB_NEUCR ;  P43496, TRXB_PENCH ;  Q7Z7S3, TRXB_PNECA ;
DR   Q8J0U0, TRXB_PNEJI ;  Q1RJD8, TRXB_RICBR ;  Q92I02, TRXB_RICCN ;
DR   Q4ULP1, TRXB_RICFE ;  Q9ZD97, TRXB_RICPR ;  Q68WT3, TRXB_RICTY ;
DR   Q92375, TRXB_SCHPO ;  Q8T6Z1, TRXB_SPIBA ;  Q5HHQ4, TRXB_STAAC ;
DR   P66010, TRXB_STAAM ;  P99101, TRXB_STAAN ;  Q6GIM7, TRXB_STAAR ;
DR   Q6GB66, TRXB_STAAS ;  P66011, TRXB_STAAW ;  Q5HQW4, TRXB_STAEQ ;
DR   Q8CPY8, TRXB_STAES ;  Q05741, TRXB_STRCL ;  P52215, TRXB_STRCO ;
DR   O83790, TRXB_TREPA ;  Q9PR71, TRXB_UREPA ;  Q9KSS4, TRXB_VIBCH ;
DR   P80892, TRXB_VIBFI ;  Q6C7L4, TRXB_YARLI ;  O62768, TRXR1_BOVIN;
DR   Q17745, TRXR1_CAEEL;  P91938, TRXR1_DROME;  B9A1H3, TRXR1_EMIHU;
DR   Q16881, TRXR1_HUMAN;  Q9JMH6, TRXR1_MOUSE;  Q9MYY8, TRXR1_PIG  ;
DR   Q5NVA2, TRXR1_PONAB;  O89049, TRXR1_RAT  ;  Q9N2I8, TRXR2_BOVIN;
DR   Q9VNT5, TRXR2_DROME;  Q9NNW7, TRXR2_HUMAN;  Q9JLT4, TRXR2_MOUSE;
DR   P61076, TRXR2_PLAF7;  Q9Z0J5, TRXR2_RAT  ;  Q86VQ6, TRXR3_HUMAN;
DR   Q99MD6, TRXR3_MOUSE;  Q25861, TRXR_PLAF5 ;
//
ID   1.8.1.10
DE   CoA-glutathione reductase.
AN   CoA-glutathione reductase (NADPH).
AN   Coenzyme A disulfide-glutathione reductase.
AN   Coenzyme A glutathione disulfide reductase.
AN   NADPH-dependent coenzyme A-SS-glutathione reductase.
AN   NADPH:CoA-glutathione oxidoreductase.
CA   CoA + glutathione + NADP(+) = CoA-glutathione + NADPH.
CF   Flavoprotein.
CC   -!- The substrate is a mixed disulfide.
CC   -!- May be identical to EC 1.8.1.9.
CC   -!- Formerly EC 1.6.4.6.
//
ID   1.8.1.11
DE   Asparagusate reductase.
AN   Asparagusate dehydrogenase.
AN   Asparagusate reductase (NADH).
AN   Asparagusic dehydrogenase.
AN   NADH:asparagusate oxidoreductase.
CA   3-mercapto-2-mercaptomethylpropanoate + NAD(+) = asparagusate + NADH.
CC   -!- Also acts on lipoate.
CC   -!- Formerly EC 1.6.4.7.
//
ID   1.8.1.12
DE   Trypanothione-disulfide reductase.
AN   N(1),N(8)-bis(glutathionyl)spermidine reductase.
AN   NADPH:trypanothione oxidoreductase.
AN   Trypanothione reductase.
CA   Trypanothione + NADP(+) = trypanothione disulfide + NADPH.
CF   FAD.
CC   -!- Trypanothione disulfide is the oxidized form of N(1),N(8)-
CC       bis(glutathionyl)-spermidine from the insect-parasitic trypanosomatid
CC       Crithidia fasciculata.
CC   -!- The activity is dependent on a redox-active cystine at the active
CC       center (cf. EC 1.8.1.7).
CC   -!- Formerly EC 1.6.4.8.
PR   PROSITE; PDOC00073;
DR   P39040, TYTR_CRIFA ;  P39050, TYTR_LEIDO ;  P39051, TYTR_TRYBB ;
DR   P13110, TYTR_TRYCO ;  P28593, TYTR_TRYCR ;
//
ID   1.8.1.13
DE   Bis-gamma-glutamylcystine reductase.
AN   Bis-gamma-glutamylcystine reductase (NADPH).
AN   NADPH:bis-gamma-glutamylcysteine oxidoreductase.
CA   2 gamma-glutamylcysteine + NADP(+) = bis-gamma-glutamylcystine + NADPH.
CC   -!- Highly specific.
CC   -!- Not identical with EC 1.8.1.7 or EC 1.8.1.14.
CC   -!- Formerly EC 1.6.4.9.
//
ID   1.8.1.14
DE   CoA-disulfide reductase.
AN   CoA-disulfide reductase (NAD(P)H).
AN   CoADR.
AN   Coenzyme A disulfide reductase.
AN   NADH:CoA-disulfide oxidoreductase.
CA   2 CoA + NAD(P)(+) = CoA-disulfide + NAD(P)H.
CF   FAD.
CC   -!- While the enzyme from Staphylococcus aureus has a strong preference
CC       for NADPH, that from the thermophilic archaea Pyrococcus horikoshii
CC       can use both NADH and NADPH efficiently.
CC   -!- Not identical with EC 1.8.1.6, EC 1.8.1.7, or EC 1.8.1.13.
CC   -!- Formerly EC 1.6.4.10.
DR   Q9UYU5, CDR_PYRAB  ;  Q8U1M0, CDR_PYRFU  ;  O58308, CDR_PYRHO  ;
DR   Q5JGP4, CDR_PYRKO  ;  A7X0I7, CDR_STAA1  ;  A6U077, CDR_STAA2  ;
DR   Q2FIA5, CDR_STAA3  ;  O52582, CDR_STAA8  ;  A5IRE8, CDR_STAA9  ;
DR   Q2YWW1, CDR_STAAB  ;  Q5HHB4, CDR_STAAC  ;  A6QFI1, CDR_STAAE  ;
DR   Q99VC0, CDR_STAAM  ;  Q7A6H1, CDR_STAAN  ;  Q6GIB7, CDR_STAAR  ;
DR   Q6GAV6, CDR_STAAS  ;  A8Z076, CDR_STAAT  ;  Q8NXE8, CDR_STAAW  ;
DR   Q5HQI9, CDR_STAEQ  ;  Q8CPT6, CDR_STAES  ;  Q4L4Y7, CDR_STAHJ  ;
DR   Q49WB0, CDR_STAS1  ;
//
ID   1.8.1.15
DE   Mycothione reductase.
AN   Mycothiol-disulfide reductase.
CA   2 mycothiol + NAD(P)(+) = mycothione + NAD(P)H.
CF   FAD.
CC   -!- No activity with glutathione, trypanothione or coenzyme A as
CC       substrate.
DR   O07927, MTR_MYCTU  ;
//
ID   1.8.1.16
DE   Glutathione amide reductase.
AN   GAR.
CA   2 glutathione amide + NAD(+) = glutathione amide disulfide + NADH.
CC   -!- The enzyme restores glutathione amide disulfide, which is produced
CC       during the reduction of peroxide by EC 1.11.1.17 back to glutathione
CC       amide (it catalyzes the reaction in the opposite direction to that
CC       shown).
CC   -!- The enzyme belongs to the family of flavoprotein disulfide
CC       oxidoreductases, but unlike other members of the family, which are
CC       specific for NADPH, it prefers NADH.
PR   PROSITE; PDOC00073;
//
ID   1.8.1.17
DE   Dimethylsulfone reductase.
CA   Dimethyl sulfoxide + NAD(+) + H(2)O = dimethyl sulfone + NADH.
CC   -!- A molybdoprotein.
//
ID   1.8.2.1
DE   Sulfite dehydrogenase.
CA   Sulfite + 2 ferricytochrome c + H(2)O = sulfate + 2 ferrocytochrome c +
CA   2 H(+).
CC   -!- Associated with cytochrome c-551.
//
ID   1.8.2.2
DE   Thiosulfate dehydrogenase.
AN   Tetrathionate synthase.
CA   2 thiosulfate + 2 ferricytochrome c = tetrathionate +
CA   2 ferrocytochrome c.
//
ID   1.8.2.3
DE   Sulfide-cytochrome-c reductase (flavocytochrome c).
CA   Hydrogen sulfide + 2 ferricytochrome c = sulfur + 2 ferrocytochrome c.
CF   FAD; Heme c.
DR   Q06530, DHSU_ALLVD ;  P20161, DHSU_CHLLT ;
//
ID   1.8.2.4
DE   Dimethyl sulfide:cytochrome c2 reductase.
CA   Dimethyl sulfide + 2 ferricytochrome c2 + H(2)O = dimethyl sulfoxide +
CA   2 ferrocytochrome c2.
CF   Heme b; Iron-sulfur; Molybdopterin guanine dinucleotide.
CC   -!- The enzyme from Rhodovulum sulfidophilum binds molybdopterin guanine
CC       dinucleotide, heme b and [4Fe-4S] clusters.
DR   Q8GPG4, DDHA_RHOSU ;
//
ID   1.8.3.1
DE   Sulfite oxidase.
CA   Sulfite + O(2) + H(2)O = sulfate + H(2)O(2).
CF   Heme; Molybdenum.
PR   PROSITE; PDOC00170;
PR   PROSITE; PDOC00484;
DR   Q9S850, SUOX_ARATH ;  P07850, SUOX_CHICK ;  Q9VWP4, SUOX_DROME ;
DR   P51687, SUOX_HUMAN ;  Q60HD0, SUOX_MACFA ;  Q8R086, SUOX_MOUSE ;
DR   Q07116, SUOX_RAT   ;
//
ID   1.8.3.2
DE   Thiol oxidase.
AN   Sulfhydryl oxidase.
CA   4 R'C(R)SH + O(2) = 2 R'C(R)S-S(R)CR' + 2 H(2)O.
CC   -!- R may be =S or =O, or a variety of other groups.
CC   -!- The enzyme is not specific for R'.
DR   Q6GZN7, 088R_FRG3G ;  P55789, ALR_HUMAN  ;  P56213, ALR_MOUSE  ;
DR   Q63042, ALR_RAT    ;  P21050, E10R_VACCC ;  P23373, E10R_VACCW ;
DR   P33821, E10R_VAR67 ;  Q8GXX0, ERV1_ARATH ;  O14144, ERV1_SCHPO ;
DR   P27882, ERV1_YEAST ;  Q9Y806, ERV2_SCHPO ;  Q12284, ERV2_YEAST ;
DR   Q65163, FLSO_ASFB7 ;  P0C8G8, FLSO_ASFK5 ;  Q9JFM9, FLSO_ASFM2 ;
DR   P0C8G9, FLSO_ASFWA ;  Q8W4J3, QSOX1_ARATH;  O08841, QSOX1_CAVPO;
DR   Q8JGM4, QSOX1_CHICK;  O00391, QSOX1_HUMAN;  Q8BND5, QSOX1_MOUSE;
DR   Q6AUC6, QSOX1_ORYSJ;  Q6IUU3, QSOX1_RAT  ;  Q9ZU40, QSOX2_ARATH;
DR   Q6ZRP7, QSOX2_HUMAN;  Q3TMX7, QSOX2_MOUSE;  Q6AX23, QSOX2_XENLA;
DR   Q9J5C7, V093_FOWPN ;  Q196W4, VF347_IIV3 ;  Q91FH7, VF347_IIV6 ;
DR   Q5UQV6, YR368_MIMIV;  Q5UP54, YR596_MIMIV;
//
ID   1.8.3.3
DE   Glutathione oxidase.
CA   2 glutathione + O(2) = glutathione disulfide + H(2)O(2).
CF   FAD.
CC   -!- Also acts, more slowly, on L-cysteine and several other thiols.
//
ID   1.8.3.4
DE   Methanethiol oxidase.
AN   Methylmercaptan oxidase.
CA   Methanethiol + O(2) + H(2)O = formaldehyde + H(2)S + H(2)O(2).
//
ID   1.8.3.5
DE   Prenylcysteine oxidase.
AN   Prenylcysteine lyase.
CA   An S-prenyl-L-cysteine + O(2) + H(2)O = a prenal + L-cysteine + H(2)O(2).
CF   FAD.
CC   -!- Cleaves the thioether bond of S-prenyl-L-cysteines, such as
CC       S-farnesylcysteine and S-geranylgeranylcysteine.
CC   -!- N-acetyl-prenylcysteine and prenylcysteinyl peptides are not
CC       substrates.
CC   -!- May represent the final step in the degradation of prenylated
CC       proteins in mammalian tissues.
CC   -!- Originally thought to be a simple lyase, EC 4.4.1.18.
DR   Q9UHG3, PCYOX_HUMAN;  Q95KC9, PCYOX_MACFA;  Q9CQF9, PCYOX_MOUSE;
DR   Q5R748, PCYOX_PONAB;  Q99ML5, PCYOX_RAT  ;
//
ID   1.8.3.6
DE   Farnesylcysteine lyase.
AN   FC lyase.
CA   S-(2E,6E)-farnesyl-L-cysteine + O(2) + H(2)O = (2E,6E)-farnesal +
CA   L-cysteine + H(2)O(2).
CF   FAD.
CC   -!- In contrast to mammalian EC 1.8.3.5 the farnesylcysteine lyase from
CC       Arabidopsis is specific for S-farnesyl-L-cysteine and shows no
CC       activity with S-geranylgeranyl-L-cysteine.
DR   P57681, PCYOX_ARATH;
//
ID   1.8.4.1
DE   Glutathione--homocystine transhydrogenase.
CA   2 glutathione + homocystine = glutathione disulfide + 2 homocysteine.
CC   -!- The reactions catalyzed by this enzyme and by others in this subclass
CC       may be similar to those catalyzed by EC 2.5.1.18.
//
ID   1.8.4.2
DE   Protein-disulfide reductase (glutathione).
AN   Glutathione--insulin transhydrogenase.
AN   Insulin reductase.
CA   2 glutathione + protein-disulfide = glutathione disulfide + protein-
CA   dithiol.
CC   -!- Reduces insulin and some other proteins.
PR   PROSITE; PDOC00172;
DR   Q5E936, TXD12_BOVIN;  O95881, TXD12_HUMAN;  Q9CQU0, TXD12_MOUSE;
DR   Q498E0, TXD12_RAT  ;
//
ID   1.8.4.3
DE   Glutathione--CoA-glutathione transhydrogenase.
CA   CoA + glutathione disulfide = CoA-glutathione + glutathione.
//
ID   1.8.4.4
DE   Glutathione--cystine transhydrogenase.
CA   2 glutathione + cystine = oxidized glutathione + 2 cysteine.
//
ID   1.8.4.5
DE   Transferred entry: 1.8.4.13 and 1.8.4.14.
//
ID   1.8.4.6
DE   Transferred entry: 1.8.4.11.
//
ID   1.8.4.7
DE   Enzyme-thiol transhydrogenase (glutathione-disulfide).
AN   [Xanthine-dehydrogenase]:oxidized-glutathione S-oxidoreductase.
AN   Enzyme-thiol transhydrogenase (oxidized-glutathione).
AN   Glutathione-dependent thiol:disulfide oxidoreductase.
AN   Thiol:disulfide oxidoreductase.
CA   [Xanthine dehydrogenase] + glutathione disulfide = [xanthine oxidase] +
CA   2 glutathione.
CC   -!- Converts EC 1.17.1.4 into EC 1.17.3.2 in the presence of glutathione
CC       disulfide.
CC   -!- Also reduces the disulfide bond of ricin.
CC   -!- Not inhibited by Cu(2+) or thiol reagents.
//
ID   1.8.4.8
DE   Phosphoadenylyl-sulfate reductase (thioredoxin).
AN   3'-phosphoadenylylsulfate reductase.
AN   PAdoPS reductase.
AN   PAPS reductase.
AN   PAPS reductase, thioredoxin-dependent.
AN   PAPS sulfotransferase.
AN   Phosphoadenosine-phosphosulfate reductase.
AN   Thioredoxin:3'-phospho-adenylylsulfate reductase.
AN   Thioredoxin:adenosine 3'-phosphate 5'-phosphosulfate reductase.
CA   Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide =
CA   3'-phosphoadenylyl sulfate + thioredoxin.
CC   -!- Specific for PAPS.
CC   -!- The enzyme from Escherichia coli will use thioredoxins from other
CC       species.
CC   -!- Formerly EC 1.8.99.4.
DR   P94498, CYSH1_BACSU;  O06737, CYSH2_BACSU;  Q8UH67, CYSH_AGRT5 ;
DR   Q0A6T1, CYSH_ALHEH ;  B6ELM6, CYSH_ALISL ;  B4RYS5, CYSH_ALTMD ;
DR   B7GG21, CYSH_ANOFW ;  A7Z4H7, CYSH_BACA2 ;  C3P516, CYSH_BACAA ;
DR   C3L9N6, CYSH_BACAC ;  A0RBN2, CYSH_BACAH ;  Q81T49, CYSH_BACAN ;
DR   B7JG06, CYSH_BACC0 ;  Q73B76, CYSH_BACC1 ;  B7INB4, CYSH_BACC2 ;
DR   C1EMR8, CYSH_BACC3 ;  B7HHH6, CYSH_BACC4 ;  B7HKE5, CYSH_BACC7 ;
DR   A7GMW0, CYSH_BACCN ;  B9IV11, CYSH_BACCQ ;  Q81FZ1, CYSH_BACCR ;
DR   Q63DV9, CYSH_BACCZ ;  Q9KCT3, CYSH_BACHD ;  Q6HLD4, CYSH_BACHK ;
DR   A8FD22, CYSH_BACP2 ;  Q5WKF5, CYSH_BACSK ;  A9VLI9, CYSH_BACWK ;
DR   Q1LTP3, CYSH_BAUCH ;  B8D9K4, CYSH_BUCA5 ;  P57501, CYSH_BUCAI ;
DR   B8D7V6, CYSH_BUCAT ;  A8ANW8, CYSH_CITK8 ;  P56860, CYSH_DEIRA ;
DR   A7ZQK5, CYSH_ECO24 ;  B7UHH4, CYSH_ECO27 ;  B7MKM9, CYSH_ECO45 ;
DR   B7LEI1, CYSH_ECO55 ;  Q8X7U3, CYSH_ECO57 ;  B5Z3C5, CYSH_ECO5E ;
DR   B7NT99, CYSH_ECO7I ;  B7MYR0, CYSH_ECO81 ;  B7LXH5, CYSH_ECO8A ;
DR   C4ZZR6, CYSH_ECOBW ;  B1XDH5, CYSH_ECODH ;  A8A3P3, CYSH_ECOHS ;
DR   A1AEU8, CYSH_ECOK1 ;  Q0TEA4, CYSH_ECOL5 ;  Q8FEI9, CYSH_ECOL6 ;
DR   B1IUR7, CYSH_ECOLC ;  P17854, CYSH_ECOLI ;  B7N6Z6, CYSH_ECOLU ;
DR   B6I6F6, CYSH_ECOSE ;  B1LQ85, CYSH_ECOSM ;  Q1R7T6, CYSH_ECOUT ;
DR   A4WDV9, CYSH_ENT38 ;  A7MJ65, CYSH_ENTS8 ;  Q6D1A3, CYSH_ERWCT ;
DR   B2VG05, CYSH_ERWT9 ;  B7LWP0, CYSH_ESCF3 ;  Q5L2X9, CYSH_GEOKA ;
DR   C5D5A7, CYSH_GEOSW ;  A4IKB7, CYSH_GEOTN ;  Q7NK24, CYSH_GLOVI ;
DR   B5XV26, CYSH_KLEP3 ;  A6TD47, CYSH_KLEP7 ;  B1HXC6, CYSH_LYSSC ;
DR   Q11B66, CYSH_MESSB ;  B1MN34, CYSH_MYCA9 ;  P65669, CYSH_MYCBO ;
DR   A1KL82, CYSH_MYCBP ;  C1AQV5, CYSH_MYCBT ;  A5U586, CYSH_MYCTA ;
DR   P65668, CYSH_MYCTU ;  Q9JUD5, CYSH_NEIMA ;  Q9JRT1, CYSH_NEIMB ;
DR   Q8EQP2, CYSH_OCEIH ;  C6DDH2, CYSH_PECCP ;  Q7MB85, CYSH_PHOLL ;
DR   Q6LM60, CYSH_PHOPR ;  B4F233, CYSH_PROMH ;  B7VBC3, CYSH_PSEA8 ;
DR   Q02KP7, CYSH_PSEAB ;  O05927, CYSH_PSEAE ;  Q98GP9, CYSH_RHILO ;
DR   P56891, CYSH_RHIME ;  O33579, CYSH_RHITR ;  C1A1H0, CYSH_RHOE4 ;
DR   C1AUL1, CYSH_RHOOB ;  B5F429, CYSH_SALA4 ;  A9MF18, CYSH_SALAR ;
DR   Q57KH9, CYSH_SALCH ;  B5FTU1, CYSH_SALDC ;  B5QW34, CYSH_SALEP ;
DR   B5RDR9, CYSH_SALG2 ;  B4TFY3, CYSH_SALHS ;  B4T473, CYSH_SALNS ;
DR   Q5PEH9, CYSH_SALPA ;  A9N2E4, CYSH_SALPB ;  B5BEZ7, CYSH_SALPK ;
DR   Q2S5G4, CYSH_SALRD ;  B4TTX7, CYSH_SALSV ;  Q8Z460, CYSH_SALTI ;
DR   P17853, CYSH_SALTY ;  A8G9X8, CYSH_SERP5 ;  Q8EB01, CYSH_SHEON ;
DR   B2TZH2, CYSH_SHIB3 ;  Q31XM6, CYSH_SHIBS ;  Q32CG5, CYSH_SHIDS ;
DR   Q0T1I6, CYSH_SHIF8 ;  Q7UBT0, CYSH_SHIFL ;  Q3YY96, CYSH_SHISS ;
DR   Q2NVN2, CYSH_SODGM ;  Q5HKZ5, CYSH_STAEQ ;  Q8CMX3, CYSH_STAES ;
DR   Q4L9F3, CYSH_STAHJ ;  Q49UL7, CYSH_STAS1 ;  Q9ADG3, CYSH_STRCO ;
DR   Q55309, CYSH_SYNE7 ;  B1XN08, CYSH_SYNP2 ;  Q5N1N0, CYSH_SYNP6 ;
DR   P72794, CYSH_SYNY3 ;  P52672, CYSH_THIRO ;  A5F3I6, CYSH_VIBC3 ;
DR   Q9KUX2, CYSH_VIBCH ;  C3LRB8, CYSH_VIBCM ;  Q5E839, CYSH_VIBF1 ;
DR   B5FGJ0, CYSH_VIBFM ;  A7MSZ6, CYSH_VIBHB ;  Q87L92, CYSH_VIBPA ;
DR   B7VI86, CYSH_VIBSL ;  Q8CWK6, CYSH_VIBVU ;  Q7MHA7, CYSH_VIBVY ;
DR   Q8PHC7, CYSH_XANAC ;  Q3BPY3, CYSH_XANC5 ;  Q4UY09, CYSH_XANC8 ;
DR   B0RPG5, CYSH_XANCB ;  Q8P607, CYSH_XANCP ;  Q2P0H1, CYSH_XANOM ;
DR   B2SI06, CYSH_XANOP ;  B2IA30, CYSH_XYLF2 ;  Q9PD82, CYSH_XYLFA ;
DR   B0U6V9, CYSH_XYLFM ;  Q87DH1, CYSH_XYLFT ;  A1JJS4, CYSH_YERE8 ;
DR   A7FLY8, CYSH_YERP3 ;  B2K567, CYSH_YERPB ;  Q66ED2, CYSH_YERPS ;
DR   B1JJG7, CYSH_YERPY ;  Q5NRM3, CYSH_ZYMMO ;  P56859, MET16_EMENI;
DR   Q10270, MET16_SCHPO;  P18408, MET16_YEAST;
//
ID   1.8.4.9
DE   Adenylyl-sulfate reductase (glutathione).
AN   5'-adenylylsulfate reductase.
AN   AMP,sulfite:oxidized-glutathione oxidoreductase (adenosine-
AN   5'-phosphosulfate-forming).
AN   Plant-type 5'-adenylylsulfate reductase.
CA   AMP + sulfite + glutathione disulfide = adenylyl sulfate + 2 glutathione.
CC   -!- Differs from EC 1.8.99.2, in using glutathione as the reductant.
CC   -!- Glutathione can be replaced by gamma-glutamylcysteine or
CC       dithiothreitol, but not by thioredoxin, glutaredoxin or
CC       mercaptoethanol.
CC   -!- The enzyme from Arabidopsis thaliana contains a glutaredoxin-like
CC       domain.
CC   -!- Also found in other photosynthetic eukaryotes, e.g., the Madagascar
CC       periwinkle, Catharanthus roseus and the hollow green seaweed,
CC       Enteromorpha intestinalis.
DR   P92979, APR1_ARATH ;  Q6Z4A7, APR1_ORYSJ ;  P92981, APR2_ARATH ;
DR   P92980, APR3_ARATH ;
//
ID   1.8.4.10
DE   Adenylyl-sulfate reductase (thioredoxin).
AN   Thioredoxin-dependent 5'-adenylylsulfate reductase.
CA   AMP + sulfite + thioredoxin disulfide = 5'-adenylyl sulfate +
CA   thioredoxin.
CC   -!- Uses adenylyl sulfate, not phosphoadenylyl sulfate, distinguishing
CC       this enzyme from EC 1.8.4.8.
CC   -!- Uses thioredoxin as electron donor, not glutathione or other donors,
CC       distinguishing it from EC 1.8.4.9 and EC 1.8.99.2.
//
ID   1.8.4.11
DE   Peptide-methionine (S)-S-oxide reductase.
AN   Methionine S-oxide reductase.
AN   Methionine S-oxide reductase (S-form oxidizing).
AN   Methionine sulfoxide reductase.
AN   Methionine sulfoxide reductase A.
AN   Methionine sulphoxide reductase A.
AN   Peptide Met(O) reductase.
AN   Peptide methionine sulfoxide reductase.
CA   (1) Peptide-L-methionine + thioredoxin disulfide + H(2)O = peptide-L-
CA   methionine (S)-S-oxide + thioredoxin.
CA   (2) L-methionine + thioredoxin disulfide + H(2)O = L-methionine (S)-S-
CA   oxide + thioredoxin.
CC   -!- The reaction occurs in the reverse direction to that shown above.
CC   -!- Exhibits high specificity for the reduction of the S-form of
CC       L-methionine S-oxide, acting faster on the residue in a peptide than
CC       on the free amino acid.
CC   -!- On the free amino acid, it can also reduce D-methionine (S)-S-oxide
CC       but more slowly.
CC   -!- Plays a role in preventing oxidative-stress damage caused by reactive
CC       oxygen species by reducing the oxidized form of methionine back to
CC       methionine and thereby reactivating peptides that had been damaged.
CC   -!- The reaction proceeds via a sulfenic-acid intermediate.
CC   -!- Formerly EC 1.8.4.6.
DR   P0A3Q9, MSAB1_STRPN;  P0A3R0, MSAB1_STRR6;  P65443, MSAB2_STRPN;
DR   P65444, MSAB2_STRR6;  Q7XUP7, MSR21_ORYSJ;  Q7XUP6, MSR22_ORYSJ;
DR   Q9FKF7, MSRA1_ARATH;  Q9A9I6, MSRA1_CAUCR;  Q9CFC8, MSRA1_LACLA;
DR   Q8YXZ4, MSRA1_NOSS1;  Q98JV5, MSRA1_RHILO;  Q92SY7, MSRA1_RHIME;
DR   Q7UJK0, MSRA1_RHOBA;  P0A084, MSRA1_STAA8;  P0A081, MSRA1_STAAM;
DR   P0A082, MSRA1_STAAN;  Q6GH44, MSRA1_STAAR;  Q6G9J8, MSRA1_STAAS;
DR   P0A083, MSRA1_STAAW;  P72622, MSRA1_SYNY3;  Q9LY15, MSRA2_ARATH;
DR   Q9A9E9, MSRA2_CAUCR;  Q9CE42, MSRA2_LACLA;  Q8YWD8, MSRA2_NOSS1;
DR   Q98DV6, MSRA2_RHILO;  Q92LI5, MSRA2_RHIME;  Q7UJI2, MSRA2_RHOBA;
DR   P0A086, MSRA2_STAA8;  P65445, MSRA2_STAAM;  P65446, MSRA2_STAAN;
DR   Q6GGY3, MSRA2_STAAR;  Q6G9D7, MSRA2_STAAS;  P0A085, MSRA2_STAAW;
DR   P72800, MSRA2_SYNY3;  Q9LY14, MSRA3_ARATH;  Q92Y45, MSRA3_RHIME;
DR   P54150, MSRA4_ARATH;  Q336R9, MSRA4_ORYSJ;  Q9SL43, MSRA5_ARATH;
DR   Q5VPG8, MSRA5_ORYSJ;  Q9AL99, MSRAB_AGGAC;  Q93KF3, MSRAB_CAMFE;
DR   P86890, MSRAB_ENTFA;  P45213, MSRAB_HAEIN;  Q9ZMK8, MSRAB_HELPJ;
DR   O25011, MSRAB_HELPY;  P14930, MSRAB_NEIGO;  Q9JWM8, MSRAB_NEIMA;
DR   Q9K1N8, MSRAB_NEIMB;  Q9LAM9, MSRAB_STRGC;  Q99YT1, MSRAB_STRP1;
DR   P0DC40, MSRAB_STRP3;  Q5XAX5, MSRAB_STRP6;  Q8P046, MSRAB_STRP8;
DR   P0DC41, MSRAB_STRPQ;  O83641, MSRAB_TREPA;  Q9KLX6, MSRAB_VIBCH;
DR   B7H0P7, MSRA_ACIB3 ;  B7I4T7, MSRA_ACIB5 ;  B2I399, MSRA_ACIBC ;
DR   B0VL72, MSRA_ACIBS ;  A3M1W6, MSRA_ACIBT ;  B0V4P7, MSRA_ACIBY ;
DR   C1F1B8, MSRA_ACIC5 ;  Q7D255, MSRA_AGRT5 ;  A6TUE9, MSRA_ALKMQ ;
DR   A1R7D2, MSRA_ARTAT ;  B8HA70, MSRA_ARTCA ;  A0JXQ4, MSRA_ARTS2 ;
DR   A8IPQ8, MSRA_AZOC5 ;  C1DGW5, MSRA_AZOVD ;  A7Z5S2, MSRA_BACA2 ;
DR   Q9KAN8, MSRA_BACHD ;  Q65ID1, MSRA_BACLD ;  A8FEA4, MSRA_BACP2 ;
DR   P54154, MSRA_BACSU ;  P54149, MSRA_BOVIN ;  P54151, MSRA_BRANA ;
DR   B2SC53, MSRA_BRUA1 ;  Q2YJM1, MSRA_BRUA2 ;  Q576P8, MSRA_BRUAB ;
DR   A9MCZ5, MSRA_BRUC2 ;  C0RMK6, MSRA_BRUMB ;  Q8YDE7, MSRA_BRUME ;
DR   A5VVX1, MSRA_BRUO2 ;  A9WW77, MSRA_BRUSI ;  Q8FUZ0, MSRA_BRUSU ;
DR   A8FL58, MSRA_CAMJ8 ;  A7H4H5, MSRA_CAMJD ;  Q9PHN0, MSRA_CAMJE ;
DR   A1VYZ7, MSRA_CAMJJ ;  Q5HVD4, MSRA_CAMJR ;  Q7NVL7, MSRA_CHRVO ;
DR   A5CQY7, MSRA_CLAM3 ;  B0RBB1, MSRA_CLAMS ;  Q97MV3, MSRA_CLOAB ;
DR   A7FUX9, MSRA_CLOB1 ;  C3KXI0, MSRA_CLOB6 ;  A5I348, MSRA_CLOBH ;
DR   C1FPF1, MSRA_CLOBJ ;  B1IMT7, MSRA_CLOBK ;  A7GEN6, MSRA_CLOBL ;
DR   B1KU02, MSRA_CLOBM ;  Q0TM63, MSRA_CLOP1 ;  Q8XH97, MSRA_CLOPE ;
DR   A9KPX7, MSRA_CLOPH ;  Q0SPW9, MSRA_CLOPS ;  Q899M3, MSRA_CLOTE ;
DR   Q6NEL2, MSRA_CORDI ;  Q8FLU6, MSRA_COREF ;  A4QHY3, MSRA_CORGB ;
DR   Q8NLL5, MSRA_CORGL ;  C4LG69, MSRA_CORK4 ;  Q9APY4, MSRA_CORML ;
DR   B7K079, MSRA_CYAP8 ;  Q9RTB6, MSRA_DEIRA ;  Q9ZEQ8, MSRA_DICD3 ;
DR   Q551H3, MSRA_DICDI ;  P08761, MSRA_DROME ;  A7ZV98, MSRA_ECO24 ;
DR   B7UQN3, MSRA_ECO27 ;  B7MLN1, MSRA_ECO45 ;  B7LCT1, MSRA_ECO55 ;
DR   Q8XCG3, MSRA_ECO57 ;  B5Z3H5, MSRA_ECO5E ;  B7NUD2, MSRA_ECO7I ;
DR   B7MTA1, MSRA_ECO81 ;  B7M9I1, MSRA_ECO8A ;  C4ZR95, MSRA_ECOBW ;
DR   B1XDW8, MSRA_ECODH ;  A8A7X5, MSRA_ECOHS ;  Q0T9G6, MSRA_ECOL5 ;
DR   Q8FAG4, MSRA_ECOL6 ;  B1ISY2, MSRA_ECOLC ;  P0A744, MSRA_ECOLI ;
DR   B7NGF6, MSRA_ECOLU ;  B6I2D2, MSRA_ECOSE ;  B1LRA3, MSRA_ECOSM ;
DR   A4W5V5, MSRA_ENT38 ;  A7MM56, MSRA_ENTS8 ;  Q6D151, MSRA_ERWCT ;
DR   B2VHZ5, MSRA_ERWT9 ;  B7LMP0, MSRA_ESCF3 ;  P54152, MSRA_FRAAN ;
DR   A8L177, MSRA_FRASN ;  Q39Z11, MSRA_GEOMG ;  Q747V4, MSRA_GEOSL ;
DR   Q0BPD5, MSRA_GRABC ;  B0R518, MSRA_HALS3 ;  Q9HQG0, MSRA_HALSA ;
DR   Q18J40, MSRA_HALWD ;  Q7VI69, MSRA_HELHP ;  Q9UJ68, MSRA_HUMAN ;
DR   B5Y2Y3, MSRA_KLEP3 ;  A5VKT1, MSRA_LACRD ;  Q1WU33, MSRA_LACS1 ;
DR   Q9SEC2, MSRA_LACSA ;  Q38XB4, MSRA_LACSS ;  Q6AG94, MSRA_LEIXX ;
DR   Q04PP8, MSRA_LEPBJ ;  Q055M2, MSRA_LEPBL ;  Q03W54, MSRA_LEUMM ;
DR   Q92AE8, MSRA_LISIN ;  C1KWF9, MSRA_LISMC ;  Q71YF6, MSRA_LISMF ;
DR   B8DDP2, MSRA_LISMH ;  Q8Y640, MSRA_LISMO ;  A0AJW5, MSRA_LISW6 ;
DR   Q2W5W8, MSRA_MAGSA ;  Q0ATD8, MSRA_MARMM ;  Q8TQV6, MSRA_METAC ;
DR   Q12TP4, MSRA_METBU ;  Q602T2, MSRA_METCA ;  Q2FQ35, MSRA_METHJ ;
DR   A4FYX5, MSRA_METM5 ;  A9AB97, MSRA_METM6 ;  A6VFD6, MSRA_METM7 ;
DR   Q8PUD6, MSRA_METMA ;  A3CUG3, MSRA_METMJ ;  Q6LYY1, MSRA_METMP ;
DR   B8IJD1, MSRA_METNO ;  B0UCG5, MSRA_METS4 ;  O26635, MSRA_METTH ;
DR   Q9D6Y7, MSRA_MOUSE ;  B3PND9, MSRA_MYCA5 ;  P0A5L1, MSRA_MYCBO ;
DR   A1KEV7, MSRA_MYCBP ;  C1AJG2, MSRA_MYCBT ;  P47648, MSRA_MYCGE ;
DR   A4T413, MSRA_MYCGI ;  B8ZTJ5, MSRA_MYCLB ;  Q9CCZ3, MSRA_MYCLE ;
DR   B2HLR5, MSRA_MYCMM ;  Q73U14, MSRA_MYCPA ;  Q8EVK2, MSRA_MYCPE ;
DR   P75188, MSRA_MYCPN ;  Q98PE5, MSRA_MYCPU ;  A3Q7V7, MSRA_MYCSJ ;
DR   A1UNG1, MSRA_MYCSK ;  Q1B1N8, MSRA_MYCSS ;  A5TYL2, MSRA_MYCTA ;
DR   P0A5L0, MSRA_MYCTU ;  A0PWH2, MSRA_MYCUA ;  A1TH24, MSRA_MYCVP ;
DR   Q3IUS0, MSRA_NATPD ;  B9LA36, MSRA_NAUPA ;  A6Q418, MSRA_NITSB ;
DR   Q3SU08, MSRA_NITWN ;  Q5YUS0, MSRA_NOCFA ;  A6WYH5, MSRA_OCHA4 ;
DR   Q93S39, MSRA_OCHAN ;  Q9CN40, MSRA_PASMU ;  C6DDM6, MSRA_PECCP ;
DR   Q4FP80, MSRA_PELUB ;  Q7MYW1, MSRA_PHOLL ;  Q6LV65, MSRA_PHOPR ;
DR   Q6L2S4, MSRA_PICTO ;  A4SWL6, MSRA_POLSQ ;  Q48CJ2, MSRA_PSE14 ;
DR   B7V3B1, MSRA_PSEA8 ;  Q02EZ9, MSRA_PSEAB ;  Q9HUF1, MSRA_PSEAE ;
DR   Q1I3L0, MSRA_PSEE4 ;  O69761, MSRA_PSEFL ;  A4XPS6, MSRA_PSEMY ;
DR   B0KJ25, MSRA_PSEPG ;  Q88QZ8, MSRA_PSEPK ;  B1JE82, MSRA_PSEPW ;
DR   Q88AI5, MSRA_PSESM ;  Q4ZM24, MSRA_PSEU2 ;  Q4FQB0, MSRA_PSYA2 ;
DR   Q1Q8I3, MSRA_PSYCK ;  A5WC53, MSRA_PSYWF ;  Q8Y1C6, MSRA_RALSO ;
DR   Q923M1, MSRA_RAT   ;  B6IS04, MSRA_RHOCS ;  Q2RRT3, MSRA_RHORT ;
DR   A1AWS4, MSRA_RUTMC ;  Q21JK7, MSRA_SACD2 ;  B5F3D4, MSRA_SALA4 ;
DR   A8M3K6, MSRA_SALAI ;  A9MEZ2, MSRA_SALAR ;  Q57GH3, MSRA_SALCH ;
DR   B5FSB9, MSRA_SALDC ;  B5R0T7, MSRA_SALEP ;  B5R9G7, MSRA_SALG2 ;
DR   B4TFF2, MSRA_SALHS ;  B4T3H1, MSRA_SALNS ;  Q5PJ81, MSRA_SALPA ;
DR   A9N540, MSRA_SALPB ;  C0Q6H8, MSRA_SALPC ;  B5BKM8, MSRA_SALPK ;
DR   B4TT49, MSRA_SALSV ;  Q8Z150, MSRA_SALTI ;  A4X3E5, MSRA_SALTO ;
DR   Q8ZK71, MSRA_SALTY ;  Q09859, MSRA_SCHPO ;  A8G8X6, MSRA_SERP5 ;
DR   B2TZL3, MSRA_SHIB3 ;  Q31TF9, MSRA_SHIBS ;  Q328B8, MSRA_SHIDS ;
DR   Q0SXG5, MSRA_SHIF8 ;  P0A745, MSRA_SHIFL ;  Q3YUC8, MSRA_SHISS ;
DR   P54153, MSRA_SOLLC ;  Q5HG58, MSRA_STAAC ;  Q3K013, MSRA_STRA1 ;
DR   Q8E434, MSRA_STRA3 ;  Q8DYH1, MSRA_STRA5 ;  Q82I51, MSRA_STRAW ;
DR   Q9EWF7, MSRA_STRCO ;  C0MBS9, MSRA_STRE4 ;  B4U465, MSRA_STREM ;
DR   B1W2P8, MSRA_STRGG ;  Q8DSY4, MSRA_STRMU ;  Q9A149, MSRA_STRP1 ;
DR   P0DC38, MSRA_STRP3 ;  Q5XDH1, MSRA_STRP6 ;  Q8P272, MSRA_STRP8 ;
DR   Q1JD56, MSRA_STRPB ;  Q1JN29, MSRA_STRPC ;  Q1JI75, MSRA_STRPD ;
DR   A2RG28, MSRA_STRPG ;  Q48UX4, MSRA_STRPM ;  P0DC39, MSRA_STRPQ ;
DR   B5XK66, MSRA_STRPZ ;  C0MCD1, MSRA_STRS7 ;  B9DRF3, MSRA_STRU0 ;
DR   Q4J9L3, MSRA_SULAC ;  Q97Y45, MSRA_SULSO ;  Q746G0, MSRA_THET2 ;
DR   Q53W34, MSRA_THET8 ;  Q9AJF7, MSRA_THEVU ;  Q119G2, MSRA_TRIEI ;
DR   B1AIS8, MSRA_UREP2 ;  Q9PQK2, MSRA_UREPA ;  B5ZB99, MSRA_UREU1 ;
DR   A5CWI5, MSRA_VESOH ;  A5F587, MSRA_VIBC3 ;  Q9KP30, MSRA_VIBCH ;
DR   C3LRL2, MSRA_VIBCM ;  Q87SW6, MSRA_VIBPA ;  Q8DE84, MSRA_VIBVU ;
DR   Q8PNY8, MSRA_XANAC ;  Q3BX45, MSRA_XANC5 ;  Q4UR77, MSRA_XANC8 ;
DR   B0RUE7, MSRA_XANCB ;  Q8VS50, MSRA_XANCH ;  Q8PCA6, MSRA_XANCP ;
DR   Q2NZR7, MSRA_XANOM ;  B2SQI9, MSRA_XANOP ;  B2I4P8, MSRA_XYLF2 ;
DR   Q9PC45, MSRA_XYLFA ;  B0U2B7, MSRA_XYLFM ;  Q87D27, MSRA_XYLFT ;
DR   P40029, MSRA_YEAST ;  A1JIU0, MSRA_YERE8 ;  A7FMV2, MSRA_YERP3 ;
DR   Q1CBX8, MSRA_YERPA ;  B2K2M6, MSRA_YERPB ;  Q8ZB94, MSRA_YERPE ;
DR   A9R574, MSRA_YERPG ;  Q1CEI4, MSRA_YERPN ;  A4TRL2, MSRA_YERPP ;
DR   Q66F89, MSRA_YERPS ;  B1JML1, MSRA_YERPY ;
//
ID   1.8.4.12
DE   Peptide-methionine (R)-S-oxide reductase.
AN   Methionine S-oxide reductase.
AN   Methionine S-oxide reductase (R-form oxidizing).
AN   Methionine sulfoxide reductase.
AN   Methionine sulfoxide reductase B.
AN   Selenoprotein R.
CA   Peptide-L-methionine + thioredoxin disulfide + H(2)O = peptide-L-
CA   methionine (R)-S-oxide + thioredoxin.
CF   Selenium; Zinc.
CC   -!- The reaction occurs in the reverse direction to that shown above.
CC   -!- Exhibits high specificity for reduction of the R-form of methionine
CC       S-oxide, with higher activity being observed with L-methionine
CC       S-oxide than with D-methionine S-oxide.
CC   -!- While both free and protein-bound methionine (R)-S-oxide act as
CC       substrates, the activity with the peptide-bound form is far greater.
CC   -!- Plays a role in preventing oxidative-stress damage caused by reactive
CC       oxygen species by reducing the oxidized form of methionine back to
CC       methionine and thereby reactivating peptides that had been damaged.
CC   -!- The reaction proceeds via a sulfenic-acid intermediate.
CC   -!- For MsrB2 and MsrB3, thioredoxin is a poor reducing agent but
CC       thionein works well.
DR   P0A3Q9, MSAB1_STRPN;  P0A3R0, MSAB1_STRR6;  P65443, MSAB2_STRPN;
DR   P65444, MSAB2_STRR6;  Q9AL99, MSRAB_AGGAC;  Q93KF3, MSRAB_CAMFE;
DR   P86890, MSRAB_ENTFA;  P45213, MSRAB_HAEIN;  Q9ZMK8, MSRAB_HELPJ;
DR   O25011, MSRAB_HELPY;  P14930, MSRAB_NEIGO;  Q9JWM8, MSRAB_NEIMA;
DR   Q9K1N8, MSRAB_NEIMB;  Q9LAM9, MSRAB_STRGC;  Q99YT1, MSRAB_STRP1;
DR   P0DC40, MSRAB_STRP3;  Q5XAX5, MSRAB_STRP6;  Q8P046, MSRAB_STRP8;
DR   P0DC41, MSRAB_STRPQ;  O83641, MSRAB_TREPA;  Q9KLX6, MSRAB_VIBCH;
DR   Q9C8M2, MSRB1_ARATH;  Q0DC89, MSRB1_ORYSJ;  Q92RA4, MSRB1_RHIME;
DR   Q9C5C8, MSRB2_ARATH;  Q92Y46, MSRB2_RHIME;  Q9M0Z6, MSRB3_ARATH;
DR   Q6AUK5, MSRB3_ORYSJ;  Q9M0Z5, MSRB4_ARATH;  Q9ZS91, MSRB5_ARATH;
DR   Q10L32, MSRB5_ORYSJ;  Q8GWF4, MSRB6_ARATH;  Q8VY86, MSRB7_ARATH;
DR   O49707, MSRB8_ARATH;  Q84JT6, MSRB9_ARATH;  B0BYW4, MSRB_ACAM1 ;
DR   Q6FAL8, MSRB_ACIAD ;  B7H3X2, MSRB_ACIB3 ;  B7I415, MSRB_ACIB5 ;
DR   B2HYT2, MSRB_ACIBC ;  B0VR86, MSRB_ACIBS ;  A3M4Q3, MSRB_ACIBT ;
DR   B0VC45, MSRB_ACIBY ;  Q8UGX7, MSRB_AGRT5 ;  Q0A706, MSRB_ALHEH ;
DR   B4RUW0, MSRB_ALTMD ;  C1DRM1, MSRB_AZOVD ;  A7Z5S1, MSRB_BACA2 ;
DR   Q9KCX2, MSRB_BACHD ;  Q65ID2, MSRB_BACLD ;  A8FEA3, MSRB_BACP2 ;
DR   Q5WH73, MSRB_BACSK ;  P54155, MSRB_BACSU ;  Q89EM9, MSRB_BRAJA ;
DR   P65447, MSRB_BRUME ;  P65448, MSRB_BRUSU ;  B1YRN6, MSRB_BURA4 ;
DR   Q1BH71, MSRB_BURCA ;  B1JTT6, MSRB_BURCC ;  A0K833, MSRB_BURCH ;
DR   B4EBK9, MSRB_BURCJ ;  Q0BEH0, MSRB_BURCM ;  A9AJS6, MSRB_BURM1 ;
DR   A2SBI6, MSRB_BURM9 ;  Q62JM6, MSRB_BURMA ;  A1V4U8, MSRB_BURMS ;
DR   Q3JRF0, MSRB_BURP1 ;  Q63V23, MSRB_BURPS ;  Q39FG2, MSRB_BURS3 ;
DR   Q2SWN9, MSRB_BURTA ;  A4JEZ1, MSRB_BURVG ;  B8GY23, MSRB_CAUCN ;
DR   Q9A6B1, MSRB_CAUCR ;  B3PK10, MSRB_CELJU ;  Q1QXV3, MSRB_CHRSD ;
DR   Q97IU0, MSRB_CLOAB ;  Q9ZNJ9, MSRB_CLOHI ;  Q0TPZ6, MSRB_CLOP1 ;
DR   Q8XJZ6, MSRB_CLOPE ;  Q0SSL4, MSRB_CLOPS ;  Q47EU6, MSRB_DECAR ;
DR   Q9RUK6, MSRB_DEIRA ;  Q72EK2, MSRB_DESVH ;  A7ZMP8, MSRB_ECO24 ;
DR   B7USF8, MSRB_ECO27 ;  B7MAY9, MSRB_ECO45 ;  B7L6Q3, MSRB_ECO55 ;
DR   P0A748, MSRB_ECO57 ;  B5YQ71, MSRB_ECO5E ;  B7NSZ8, MSRB_ECO7I ;
DR   B7MVQ9, MSRB_ECO81 ;  B7M1J2, MSRB_ECO8A ;  C4ZZD4, MSRB_ECOBW ;
DR   B1XGN8, MSRB_ECODH ;  A8A0X0, MSRB_ECOHS ;  Q0TH50, MSRB_ECOL5 ;
DR   P0A747, MSRB_ECOL6 ;  B1IPF3, MSRB_ECOLC ;  P0A746, MSRB_ECOLI ;
DR   B7N5B4, MSRB_ECOLU ;  B6IBJ9, MSRB_ECOSE ;  B1LDV3, MSRB_ECOSM ;
DR   Q9XB39, MSRB_ENTFA ;  Q6D4P7, MSRB_ERWCT ;  B2VJ36, MSRB_ERWT9 ;
DR   B7LQ21, MSRB_ESCF3 ;  Q2SJP9, MSRB_HAHCH ;  A4G5V5, MSRB_HERAR ;
DR   B5XS71, MSRB_KLEP3 ;  A6T7R0, MSRB_KLEP7 ;  Q9CJ17, MSRB_LACLA ;
DR   A2RHS0, MSRB_LACLM ;  Q032Q9, MSRB_LACLS ;  Q88W33, MSRB_LACPL ;
DR   Q1WVT3, MSRB_LACS1 ;  Q6ADJ8, MSRB_LEIXX ;  Q72NN2, MSRB_LEPIC ;
DR   Q8F7W8, MSRB_LEPIN ;  Q92AE9, MSRB_LISIN ;  C1KWF8, MSRB_LISMC ;
DR   Q71YF7, MSRB_LISMF ;  B8DDP3, MSRB_LISMH ;  Q8Y641, MSRB_LISMO ;
DR   A0AJW4, MSRB_LISW6 ;  B1HZH4, MSRB_LYSSC ;  Q46EH1, MSRB_METBF ;
DR   Q8PWF5, MSRB_METMA ;  A2SGN7, MSRB_METPP ;  O26807, MSRB_METTH ;
DR   P47686, MSRB_MYCGE ;  P75129, MSRB_MYCPN ;  Q9CMB1, MSRB_PASMU ;
DR   C6DGV8, MSRB_PECCP ;  Q7N400, MSRB_PHOLL ;  A1VNB7, MSRB_POLNA ;
DR   Q12AE4, MSRB_POLSJ ;  Q48FR2, MSRB_PSE14 ;  A6V3R3, MSRB_PSEA7 ;
DR   B7UUZ9, MSRB_PSEA8 ;  Q02NZ0, MSRB_PSEAB ;  Q9I016, MSRB_PSEAE ;
DR   Q1ID16, MSRB_PSEE4 ;  Q4K8U5, MSRB_PSEF5 ;  C3K735, MSRB_PSEFS ;
DR   A4XVB1, MSRB_PSEMY ;  A5W756, MSRB_PSEP1 ;  Q3K935, MSRB_PSEPF ;
DR   B0KUQ0, MSRB_PSEPG ;  Q88LQ6, MSRB_PSEPK ;  B1J4W5, MSRB_PSEPW ;
DR   Q885Q1, MSRB_PSESM ;  Q4ZQC6, MSRB_PSEU2 ;  Q8XYL1, MSRB_RALSO ;
DR   Q21LK2, MSRB_SACD2 ;  B5F860, MSRB_SALA4 ;  A9MFH4, MSRB_SALAR ;
DR   B5FJF9, MSRB_SALDC ;  B4TGC8, MSRB_SALHS ;  B4T3Y1, MSRB_SALNS ;
DR   A9N292, MSRB_SALPB ;  B4TUA8, MSRB_SALSV ;  P65450, MSRB_SALTI ;
DR   P65449, MSRB_SALTY ;  A8GFD8, MSRB_SERP5 ;  Q321R4, MSRB_SHIBS ;
DR   Q32GC7, MSRB_SHIDS ;  Q0T4Y5, MSRB_SHIF8 ;  Q83L66, MSRB_SHIFL ;
DR   Q3Z2B6, MSRB_SHISS ;  A7X2A9, MSRB_STAA1 ;  A6U1P3, MSRB_STAA2 ;
DR   Q2FH15, MSRB_STAA3 ;  P0A088, MSRB_STAA8 ;  A5ISV4, MSRB_STAA9 ;
DR   Q2YY44, MSRB_STAAB ;  A6QGX4, MSRB_STAAE ;  P65451, MSRB_STAAM ;
DR   P99065, MSRB_STAAN ;  Q6GGY4, MSRB_STAAR ;  Q6G9D8, MSRB_STAAS ;
DR   A8Z402, MSRB_STAAT ;  P0A087, MSRB_STAAW ;  B9DNY9, MSRB_STACT ;
DR   Q5HPB4, MSRB_STAEQ ;  Q8CSK6, MSRB_STAES ;  Q4L6D3, MSRB_STAHJ ;
DR   Q49XN4, MSRB_STAS1 ;  Q3K1F5, MSRB_STRA1 ;  Q8E5Q9, MSRB_STRA3 ;
DR   Q8E026, MSRB_STRA5 ;  C0M8H8, MSRB_STRE4 ;  Q99ZV6, MSRB_STRP1 ;
DR   P0DC42, MSRB_STRP3 ;  Q5XCD0, MSRB_STRP6 ;  Q8P172, MSRB_STRP8 ;
DR   P0DC43, MSRB_STRPQ ;  C0MDV8, MSRB_STRS7 ;  A5GQT3, MSRB_SYNR3 ;
DR   C5BR54, MSRB_TERTT ;  Q8DJK9, MSRB_THEEB ;  Q3SJU1, MSRB_THIDA ;
DR   B8GMG5, MSRB_THISH ;  C5CNS9, MSRB_VARPS ;  A5F6R2, MSRB_VIBC3 ;
DR   Q9KQK0, MSRB_VIBCH ;  C3LNU9, MSRB_VIBCM ;  Q87MS5, MSRB_VIBPA ;
DR   Q8D849, MSRB_VIBVU ;  Q7MMC4, MSRB_VIBVY ;  B2I8Y4, MSRB_XYLF2 ;
DR   Q9PF29, MSRB_XYLFA ;  Q87AJ9, MSRB_XYLFT ;  A1JQG8, MSRB_YERE8 ;
DR   A7FI81, MSRB_YERP3 ;  Q1C7U0, MSRB_YERPA ;  B2K3R4, MSRB_YERPB ;
DR   Q8ZEK7, MSRB_YERPE ;  A9R9C4, MSRB_YERPG ;  Q1CJ76, MSRB_YERPN ;
DR   A4TJB4, MSRB_YERPP ;  Q66AP6, MSRB_YERPS ;  B1JLG2, MSRB_YERPY ;
DR   P25566, MXR2_YEAST ;
//
ID   1.8.4.13
DE   L-methionine (S)-S-oxide reductase.
AN   Acetylmethionine sulfoxide reductase.
AN   Free-methionine (S)-S-oxide reductase.
AN   FSMsr.
AN   Methionine sulfoxide reductase.
AN   Methionine-S-oxide reductase.
AN   Methyl sulfoxide reductase I and II.
CA   L-methionine + thioredoxin disulfide + H(2)O = L-methionine (S)-S-oxide +
CA   thioredoxin.
CF   NADPH.
CC   -!- The reaction occurs in the opposite direction to that given above.
CC   -!- Dithiothreitol can replace reduced thioredoxin.
CC   -!- L-methionine (R)-S-oxide is not a substrate (see EC 1.8.4.14).
CC   -!- Formerly EC 1.8.4.5.
//
ID   1.8.4.14
DE   L-methionine (R)-S-oxide reductase.
AN   Free met-R-(o) reductase.
AN   Free-methionine (R)-S-oxide reductase.
AN   FRMsr.
CA   L-methionine + thioredoxin disulfide + H(2)O = L-methionine (R)-S-oxide +
CA   thioredoxin.
CF   NADPH.
CC   -!- Unlike EC 1.8.4.12 this enzyme cannot use peptide-bound methionine
CC       (R)-S-oxide as a substrate.
CC   -!- Differs from EC 1.8.4.13, in that L-methionine (S)-S-oxide is not a
CC       substrate.
CC   -!- Formerly EC 1.8.4.5.
DR   P36088, FRMSR_YEAST;
//
ID   1.8.5.1
DE   Glutathione dehydrogenase (ascorbate).
CA   2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate.
//
ID   1.8.5.2
DE   Thiosulfate dehydrogenase (quinone).
AN   Thiosulfate oxidoreductase, tetrathionate-forming.
AN   Thiosulfate:quinone oxidoreductase.
AN   TQO.
CA   2 thiosulfate + 2 6-decylubiquinone = tetrathionate + 2 6-decylubiquinol.
CC   -!- The reaction can also proceed with ferricyanide as the electron
CC       acceptor, but more slowly.
CC   -!- Unlike EC 1.8.2.2, this enzyme cannot utilize cytochrome c as an
CC       acceptor.
//
ID   1.8.5.3
DE   Dimethylsulfoxide reductase.
AN   DMSO reductase.
CA   Dimethylsulfide + menaquinone + H(2)O = dimethylsulfoxide + menaquinol.
CF   Iron-sulfur; Molybdopterin.
CC   -!- Also reduces pyridine N-oxide and trimethylamine N-oxide, with lower
CC       activity, to the corresponding amines.
//
ID   1.8.5.4
DE   Sulfide:quinone reductase.
CA   n sulfide + n quinone = polysulfide + n quinol.
CF   FAD.
CC   -!- Ubiquinone, plastoquinone or menaquinone can act as acceptor in
CC       different species.
CC   -!- This enzyme catalyzes the formation of sulfur globules.
CC   -!- It is also an important step in anoxygenic bacterial photosynthesis.
//
ID   1.8.6.1
DE   Transferred entry: 2.5.1.18.
//
ID   1.8.7.1
DE   Sulfite reductase (ferredoxin).
CA   Hydrogen sulfide + 6 oxidized ferredoxin + 3 H(2)O = sulfite + 6 reduced
CA   ferredoxin + 6 H(+).
CF   Iron.
PR   PROSITE; PDOC00314;
DR   Q73YC1, SIR1_MYCPA ;  Q73XV0, SIR2_MYCPA ;  Q7TYP6, SIR_MYCBO  ;
DR   P71753, SIR_MYCTU  ;  P30008, SIR_SYNE7  ;  P72854, SIR_SYNY3  ;
//
ID   1.8.7.2
DE   Ferredoxin:thioredoxin reductase.
CA   2 reduced ferredoxin + thioredoxin disulfide = 2 oxidized ferredoxin +
CA   thioredoxin + 2 H(+).
CF   Iron-sulfur.
CC   -!- The enzyme contains a [4Fe-4S] cluster and internal disulfide.
CC   -!- It forms a mixed disulfide with thioredoxin on one side, and docks
CC       ferredoxin on the other side, enabling two one-electron transfers.
CC   -!- The reduced thioredoxins generated by the enzyme activate the Calvin
CC       cycle enzymes EC 3.1.3.11, EC 3.1.3.37 and EC 2.7.1.19 as well as
CC       other chloroplast enzymes by disulfide reduction.
DR   P41348, FTRC1_SPIOL;  P41349, FTRC2_SPIOL;  Q9SJ89, FTRC_ARATH ;
DR   Q9TM25, FTRC_CYACA ;  O78461, FTRC_GUITH ;  P41347, FTRC_MAIZE ;
DR   Q6K471, FTRC_ORYSJ ;  P51386, FTRC_PORPU ;  Q1XDA1, FTRC_PORYE ;
DR   O49856, FTRC_SOYBN ;
//
ID   1.8.98.1
DE   CoB--CoM heterodisulfide reductase.
AN   Heterodisulfide reductase.
AN   Soluble heterodisulfide reductase.
CA   Coenzyme B + coenzyme M + methanophenazine =
CA   N-(7-((2-sulfoethyl)dithio)heptanoyl)-O(3)-phospho-L-threonine +
CA   dihydromethanophenazine.
CF   Heme; Iron-sulfur.
CC   -!- Found in methanogenic archaea, particularly Methanosarcina species,
CC       and regenerates coenzyme M and coenzyme B after the action of
CC       EC 2.8.4.1.
CC   -!- Highly specific for both coenzyme M and coenzyme B.
CC   -!- Reacts with various phenazine derivatives, including
CC       2-hydroxyphenazine and 2-bromophenazine.
CC   -!- Formerly EC 1.12.99.2.
DR   Q8TYP4, HDRA1_METKA;  P96801, HDRA2_METKA;  Q8TM02, HDRA_METAC ;
DR   P60200, HDRA_METJA ;  Q8Q0T0, HDRA_METMA ;  Q6LWL2, HDRA_METMP ;
DR   O27434, HDRA_METTH ;  Q50756, HDRA_METTM ;  Q58153, HDRB1_METJA;
DR   Q58273, HDRB2_METJA;  Q8TIB8, HDRB_METAC ;  Q8TXT8, HDRB_METKA ;
DR   Q8PY83, HDRB_METMA ;  O27907, HDRB_METTH ;  Q50755, HDRB_METTM ;
DR   Q58154, HDRC1_METJA;  Q58274, HDRC2_METJA;  Q8TIB9, HDRC_METAC ;
DR   Q8TXT7, HDRC_METKA ;  Q8PY84, HDRC_METMA ;  O27906, HDRC_METTH ;
DR   Q50754, HDRC_METTM ;  Q8TSV7, HDRD_METAC ;  P96797, HDRD_METBF ;
DR   Q8PVW3, HDRD_METMA ;  Q8TSV8, HDRE_METAC ;  P96796, HDRE_METBF ;
DR   Q8PVW4, HDRE_METMA ;
//
ID   1.8.98.2
DE   Sulfiredoxin.
AN   Peroxiredoxin-(S-hydroxy-S-oxocysteine) reductase.
CA   Peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH = peroxiredoxin-
CA   (S-hydroxycysteine) + ADP + phosphate + R-S-S-R.
CC   -!- In the course of the reaction of EC 1.11.1.15, its cysteine residue
CC       is alternately oxidized to the sulfenic acid, S-hydroxycysteine,
CC       and reduced back to cysteine.
CC   -!- Occasionally the S-hydroxycysteine residue is further oxidized to the
CC       sulfinic acid S-hydroxy-S-oxocysteine, thereby inactivating the
CC       enzyme.
CC   -!- The reductase provides a mechanism for regenerating the active form
CC       of peroxiredoxin, i.e. the peroxiredoxin-(S-hydroxycysteine) form.
CC   -!- Apparently the reductase first catalyzes the phosphorylation of the
CC       -S(O)-OH group by ATP to give -S(O)-O-P, which is attached to the
CC       peroxiredoxin by a cysteine residue, forming an -S(O)-S- link between
CC       the two enzymes.
CC   -!- Attack by a thiol splits this bond, leaving the peroxiredoxin as the
CC       sulfenic acid and the reductase as the thiol.
DR   Q9URV9, SRX1_SCHPO ;  P36077, SRX1_YEAST ;  Q9BYN0, SRXN1_HUMAN;
DR   Q9D975, SRXN1_MOUSE;  Q9VX10, SRX_DROME  ;
//
ID   1.8.99.1
DE   Sulfite reductase.
CA   H(2)S + acceptor + 3 H(2)O = SO(3)(2-) + reduced acceptor.
CF   Iron.
CC   -!- A stoichiometry of six molecules of reduced methyl viologen per
CC       molecule of sulfide formed was found.
//
ID   1.8.99.2
DE   Adenylyl-sulfate reductase.
CA   AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor.
CF   FAD; Iron.
CC   -!- Methyl viologen can act as acceptor.
//
ID   1.8.99.3
DE   Hydrogensulfite reductase.
AN   Bisulfite reductase.
AN   Desulfofuscidin.
AN   Desulforubidin.
AN   Desulfoviridin.
AN   Dissimilatory sulfite reductase.
CA   (O(3)S.S.SO(3))(2-) + acceptor + 2 H(2)O + OH(-) = 3 HSO(3)(-) + reduced
CA   acceptor.
CF   Iron-sulfur; Siroheme.
CC   -!- Methyl viologen can act as acceptor.
CC   -!- A group of sirohemoproteins containing iron-sulfur centers (P-582).
DR   O33998, DSRA_ALLVD ;  Q59109, DSRA_ARCFU ;  Q59110, DSRB_ARCFU ;
DR   P94693, DSVA_DESGI ;  P45574, DSVA_DESVH ;  P94694, DSVB_DESGI ;
DR   P45575, DSVB_DESVH ;  P45573, DSVC_DESVH ;
//
ID   1.8.99.4
DE   Transferred entry: 1.8.4.8.
//
ID   1.9.3.1
DE   Cytochrome-c oxidase.
AN   Complex IV (mitochondrial electron transport).
AN   Cytochrome a3.
AN   Cytochrome aa3.
AN   Cytochrome oxidase.
AN   Warburg's respiratory enzyme.
CA   4 ferrocytochrome c + O(2) + 4 H(+) = 4 ferricytochrome c + 2 H(2)O.
CF   Copper.
CC   -!- The reduction of O(2) to water is accompanied by the extrusion of
CC       four protons from the intramitochondrial compartment.
CC   -!- Several bacteria appear to contain analogous oxidases.
PR   PROSITE; PDOC00074;
PR   PROSITE; PDOC00075;
PR   PROSITE; PDOC00663;
DR   P98005, COX13_THET8;  P98057, COX14_BRAJA;  Q5YRP8, COX1A_NOCFA;
DR   P08305, COX1A_PARDE;  Q82AK9, COX1A_STRAW;  Q9X813, COX1A_STRCO;
DR   Q5Z0K2, COX1B_NOCFA;  P98002, COX1B_PARDE;  Q828X4, COX1B_STRAW;
DR   Q9K451, COX1B_STRCO;  Q37370, COX1_ACACA ;  B0FWC7, COX1_AEDAE ;
DR   P68540, COX1_AEGCO ;  P48887, COX1_ALBCO ;  Q09333, COX1_ALBTU ;
DR   P80440, COX1_ALLMA ;  P29643, COX1_AMICA ;  P50656, COX1_ANAPL ;
DR   P34838, COX1_ANOGA ;  P33504, COX1_ANOQU ;  P20374, COX1_APILI ;
DR   O03515, COX1_APTAU ;  P60620, COX1_ARATH ;  Q37705, COX1_ARTSF ;
DR   P24881, COX1_ASCSU ;  P62514, COX1_ASHGO ;  Q33820, COX1_ASTPE ;
DR   P29644, COX1_ATRSP ;  P16262, COX1_BACP3 ;  Q04440, COX1_BACPE ;
DR   P24010, COX1_BACSU ;  Q599A1, COX1_BALBO ;  P41293, COX1_BALMU ;
DR   P24983, COX1_BALPH ;  P24794, COX1_BETVU ;  Q36724, COX1_BLAGE ;
DR   Q6EMS9, COX1_BOSIN ;  Q5Y4Q8, COX1_BOSMU ;  P00396, COX1_BOVIN ;
DR   P31833, COX1_BRAJA ;  Q94WR7, COX1_BUTBU ;  P24893, COX1_CAEEL ;
DR   P0C8K9, COX1_CANAL ;  Q9ZZ64, COX1_CANFA ;  Q85QA3, COX1_CANGA ;
DR   Q1HKA1, COX1_CANLU ;  Q33375, COX1_CANSI ;  Q36347, COX1_CAPHI ;
DR   O78681, COX1_CARAU ;  O03521, COX1_CASBE ;  O03198, COX1_CERSI ;
DR   P18943, COX1_CHICK ;  P08681, COX1_CHLRE ;  P50668, COX1_CHOBI ;
DR   P48866, COX1_CHOCR ;  P50669, COX1_CHOFU ;  P67793, COX1_CHOOC ;
DR   P67794, COX1_CHOPI ;  P50671, COX1_CHORO ;  Q9B229, COX1_CHRKN ;
DR   O99041, COX1_COLPO ;  Q6NFM3, COX1_CORDI ;  Q8FMT1, COX1_COREF ;
DR   Q79VD7, COX1_CORGL ;  P24984, COX1_COTJA ;  Q6EGJ1, COX1_CRANE ;
DR   Q6EGJ0, COX1_CRAZI ;  P98003, COX1_CRION ;  P48867, COX1_CYACA ;
DR   P24985, COX1_CYPCA ;  Q9MIY8, COX1_DANRE ;  O21327, COX1_DASNO ;
DR   A9RAH5, COX1_DEBHA ;  Q2LCQ6, COX1_DICCI ;  O21042, COX1_DICDI ;
DR   P41310, COX1_DIDMA ;  O79548, COX1_DINSE ;  Q34345, COX1_DROMA ;
DR   P00399, COX1_DROME ;  O03524, COX1_DRONO ;  Q34391, COX1_DROSE ;
DR   Q34388, COX1_DROSI ;  P00400, COX1_DROYA ;  Q8W9N4, COX1_DUGDU ;
DR   Q2I3H2, COX1_ELEMA ;  P00402, COX1_EMENI ;  Q33439, COX1_EPHEQ ;
DR   P92477, COX1_EQUAS ;  P48888, COX1_FELCA ;  P34188, COX1_FORLA ;
DR   Q36775, COX1_GADMO ;  Q6EGH9, COX1_GEOBE ;  P29645, COX1_GEOSD ;
DR   Q6EGH8, COX1_GEOTE ;  P29646, COX1_GOMVA ;  P38595, COX1_HALGR ;
DR   P33518, COX1_HALSA ;  Q9ZZ08, COX1_HAPMA ;  Q9ZZY9, COX1_HIPAM ;
DR   P48659, COX1_HORSE ;  P00395, COX1_HUMAN ;  Q7GEN7, COX1_HYLLA ;
DR   Q34800, COX1_HYLSY ;  P20386, COX1_KLULA ;  O03167, COX1_LATCH ;
DR   P14544, COX1_LEITA ;  Q8LX30, COX1_LEMCA ;  P29647, COX1_LEPOC ;
DR   Q36421, COX1_LOCMI ;  Q9TGE6, COX1_LOLFO ;  Q8WEW4, COX1_LOLPE ;
DR   Q9TA27, COX1_LOXAF ;  Q34941, COX1_LUMTE ;  P92661, COX1_MACRO ;
DR   P08742, COX1_MAIZE ;  Q38PS0, COX1_MAMPR ;  P26856, COX1_MARPO ;
DR   P29648, COX1_MEGAT ;  Q35101, COX1_METSE ;  P00397, COX1_MOUSE ;
DR   P63853, COX1_MYCBO ;  Q9CBQ5, COX1_MYCLE ;  Q73VC3, COX1_MYCPA ;
DR   P63852, COX1_MYCTU ;  P41774, COX1_MYTED ;  O21079, COX1_MYXGL ;
DR   P03945, COX1_NEUCR ;  O03539, COX1_NOTPE ;  Q9G6J1, COX1_OCTVU ;
DR   P08743, COX1_OENBE ;  P48170, COX1_ONCMY ;  Q36452, COX1_ORNAN ;
DR   Q6EGI5, COX1_ORTCH ;  Q6EGI2, COX1_ORTGR ;  Q6EGI3, COX1_ORTHI ;
DR   Q6EGI4, COX1_ORTUN ;  P14578, COX1_ORYSJ ;  Q9B840, COX1_OSTNU ;
DR   P29649, COX1_PANBU ;  Q9T9X0, COX1_PANPA ;  Q9T9W1, COX1_PANTR ;
DR   Q6EGI0, COX1_PAPBU ;  Q9ZXY2, COX1_PAPHA ;  P12700, COX1_PARLI ;
DR   P05489, COX1_PARTE ;  Q00502, COX1_PARVE ;  P12786, COX1_PEA   ;
DR   Q96000, COX1_PECMA ;  O79672, COX1_PELSU ;  Q35536, COX1_PETMA ;
DR   Q00527, COX1_PHOVI ;  Q02211, COX1_PHYME ;  Q07434, COX1_PHYPO ;
DR   P48868, COX1_PICCA ;  O79876, COX1_PIG   ;  P25001, COX1_PISOC ;
DR   O99252, COX1_PLABE ;  O99255, COX1_PLACH ;  Q9TGD8, COX1_PLADA ;
DR   Q02766, COX1_PLAFA ;  P20681, COX1_PODAN ;  Q95911, COX1_POLOR ;
DR   P29650, COX1_POLSP ;  P29651, COX1_POLSX ;  P29652, COX1_POMNI ;
DR   P92692, COX1_PONAB ;  Q05143, COX1_PROWI ;  O79429, COX1_RABIT ;
DR   P60621, COX1_RAPSA ;  P05503, COX1_RAT   ;  O03546, COX1_RHEAM ;
DR   Q08855, COX1_RHILE ;  O99818, COX1_RHISA ;  Q96062, COX1_RHIUN ;
DR   P98059, COX1_RHOCA ;  P33517, COX1_RHOSH ;  Q1RI42, COX1_RICBR ;
DR   Q92I67, COX1_RICCN ;  Q4ULU5, COX1_RICFE ;  O54069, COX1_RICPR ;
DR   P98001, COX1_SACDO ;  Q9ZZM6, COX1_SALSA ;  P29653, COX1_SALTR ;
DR   P29654, COX1_SCAPL ;  P07657, COX1_SCHPO ;  O79403, COX1_SCYCA ;
DR   Q8WEW3, COX1_SEPOF ;  Q957T2, COX1_SEPPH ;  O78749, COX1_SHEEP ;
DR   P05502, COX1_SORBI ;  P07506, COX1_SOYBN ;  Q9ZZ52, COX1_SQUAC ;
DR   O21399, COX1_STRCA ;  P15544, COX1_STRPU ;  Q06473, COX1_SYNY3 ;
DR   Q4JQI5, COX1_TETNG ;  P11947, COX1_TETPY ;  Q4UJ69, COX1_THEAN ;
DR   Q36097, COX1_THEPA ;  Q5SJ79, COX1_THET8 ;  Q56408, COX1_THETH ;
DR   P50676, COX1_THEVL ;  O03554, COX1_TINMA ;  Q01555, COX1_TRIRU ;
DR   P04371, COX1_TRYBB ;  Q0H8Y4, COX1_USTMA ;  A6H4Q6, COX1_VANPO ;
DR   P68539, COX1_WHEAT ;  P00398, COX1_XENLA ;  Q9B6E7, COX1_YARLI ;
DR   P00401, COX1_YEAST ;  Q6EGH7, COX1_ZYGTR ;  P29870, COX2_ACHDO ;
DR   P29871, COX2_ADABI ;  P50692, COX2_AEDAE ;  P48889, COX2_ALBCO ;
DR   Q09334, COX2_ALBTU ;  O47870, COX2_ALLMI ;  P29655, COX2_AMICA ;
DR   P98019, COX2_ANAPL ;  P34840, COX2_ANOGA ;  P33505, COX2_ANOQU ;
DR   P50267, COX2_APIFL ;  P50268, COX2_APIKO ;  P20375, COX2_APILI ;
DR   O03889, COX2_APTAU ;  P93285, COX2_ARATH ;  Q37706, COX2_ARTSF ;
DR   P24882, COX2_ASCSU ;  Q7YFV7, COX2_ASHGO ;  Q37411, COX2_ASTPE ;
DR   P29656, COX2_ATRSP ;  Q03438, COX2_BACP3 ;  Q04441, COX2_BACPE ;
DR   P24011, COX2_BACSU ;  P98012, COX2_BETVU ;  O47428, COX2_BRAFL ;
DR   O79417, COX2_BRALA ;  P43369, COX2_BREAN ;  P43370, COX2_BRECS ;
DR   P43372, COX2_BRENA ;  Q8HEC3, COX2_CAEBR ;  P24894, COX2_CAEEL ;
DR   Q8SEM9, COX2_CAERE ;  P50666, COX2_CAIMO ;  Q9B8D8, COX2_CANAL ;
DR   P43373, COX2_CANGA ;  O78682, COX2_CARAU ;  O03890, COX2_CASBE ;
DR   P18944, COX2_CHICK ;  P98025, COX2_CHOBI ;  P48869, COX2_CHOCR ;
DR   P84288, COX2_CHOFU ;  P84289, COX2_CHOOC ;  P84290, COX2_CHOPI ;
DR   P98030, COX2_CHORO ;  Q6NG98, COX2_CORDI ;  Q8FNQ7, COX2_COREF ;
DR   Q8NNK2, COX2_CORGL ;  P50684, COX2_COTJA ;  P29872, COX2_CTEFE ;
DR   P50693, COX2_CULQU ;  P48870, COX2_CYACA ;  P47918, COX2_CYBMR ;
DR   P06029, COX2_CYBSA ;  P24987, COX2_CYPCA ;  Q9MIY7, COX2_DANRE ;
DR   P27168, COX2_DAUCA ;  A9RAG1, COX2_DEBHA ;  P43374, COX2_DEKBR ;
DR   O79549, COX2_DINSE ;  Q85TA0, COX2_DROAI ;  P84201, COX2_DROAL ;
DR   P29856, COX2_DROAM ;  P84202, COX2_DROAT ;  P84287, COX2_DROAZ ;
DR   P29859, COX2_DROBF ;  P29860, COX2_DROLO ;  P00408, COX2_DROME ;
DR   P67797, COX2_DROMI ;  O03891, COX2_DRONO ;  P67795, COX2_DRONR ;
DR   P67798, COX2_DROPE ;  P67799, COX2_DROPS ;  P50253, COX2_DROSI ;
DR   P29865, COX2_DROSU ;  P67796, COX2_DROTO ;  P00409, COX2_DROYA ;
DR   P43375, COX2_EENNA ;  P13588, COX2_EMENI ;  P29873, COX2_EXERO ;
DR   P34189, COX2_FORLA ;  Q37741, COX2_GADMO ;  P29874, COX2_GALME ;
DR   P29657, COX2_GEOSD ;  P29658, COX2_GOMVA ;  P20387, COX2_KLULA ;
DR   P43376, COX2_LACTC ;  P29875, COX2_LASSP ;  O03848, COX2_LATCH ;
DR   P14545, COX2_LEITA ;  P29659, COX2_LEPOC ;  P14573, COX2_LOCMI ;
DR   Q37545, COX2_LUMTE ;  P00412, COX2_MAIZE ;  P26857, COX2_MARPO ;
DR   P29660, COX2_MEGAT ;  O47496, COX2_METSE ;  P63855, COX2_MYCBO ;
DR   Q9CCF1, COX2_MYCLE ;  Q73YL5, COX2_MYCPA ;  P63854, COX2_MYCTU ;
DR   Q00227, COX2_MYTED ;  Q9G2X2, COX2_MYXGL ;  P00411, COX2_NEUCR ;
DR   Q5YZ37, COX2_NOCFA ;  O03892, COX2_NOTPE ;  P05490, COX2_OENBE ;
DR   P29876, COX2_ONCFA ;  P48171, COX2_ONCMY ;  P04373, COX2_ORYSJ ;
DR   P08306, COX2_PARDE ;  P12701, COX2_PARLI ;  P08748, COX2_PARPR ;
DR   P08749, COX2_PARTE ;  P08744, COX2_PEA   ;  O79673, COX2_PELSU ;
DR   P29877, COX2_PERAM ;  Q37604, COX2_PETMA ;  Q02212, COX2_PHYME ;
DR   P48871, COX2_PICCA ;  P25002, COX2_PISOC ;  P29163, COX2_PNECA ;
DR   P20682, COX2_PODAN ;  Q96183, COX2_POLOR ;  P29661, COX2_POLSX ;
DR   O03893, COX2_RHEAM ;  O99819, COX2_RHISA ;  Q03736, COX2_RHOSH ;
DR   Q1RI44, COX2_RICBR ;  Q92I65, COX2_RICCN ;  Q4ULU3, COX2_RICFE ;
DR   Q9ZDC6, COX2_RICPR ;  P43377, COX2_SACEX ;  Q9XLW8, COX2_SACKL ;
DR   Q37677, COX2_SALSA ;  P29662, COX2_SCAPL ;  P29878, COX2_SCHGR ;
DR   P21534, COX2_SCHPO ;  O79404, COX2_SCYCA ;  P98021, COX2_SIMVI ;
DR   P29879, COX2_SITGR ;  Q3T4C0, COX2_SMICU ;  P80498, COX2_SOLTU ;
DR   P05491, COX2_SOYBN ;  Q9ZZ51, COX2_SQUAC ;  Q82AL0, COX2_STRAW ;
DR   O21400, COX2_STRCA ;  Q9X814, COX2_STRCO ;  P15545, COX2_STRPU ;
DR   P29880, COX2_SYMST ;  Q06474, COX2_SYNY3 ;  Q4JQI4, COX2_TETNG ;
DR   Q5SJ80, COX2_THET8 ;  P98052, COX2_THETH ;  P98054, COX2_THEVL ;
DR   O03895, COX2_TINMA ;  Q01556, COX2_TRIRU ;  P04372, COX2_TRYBB ;
DR   P98023, COX2_TRYCR ;  Q0H8Y7, COX2_USTMA ;  A6H4Q5, COX2_VANPO ;
DR   P32646, COX2_VIGUN ;  P00413, COX2_WHEAT ;  P00407, COX2_XENLA ;
DR   Q9B6D5, COX2_YARLI ;  P00410, COX2_YEAST ;  P98048, COX2_YPOMA ;
DR   P29881, COX2_ZOOAN ;  Q37374, COX3_ACACA ;  B0FWD1, COX3_AEDAE ;
DR   Q36952, COX3_AEGCO ;  P48891, COX3_ALBCO ;  P80439, COX3_ALLMA ;
DR   P50657, COX3_ANAPL ;  P34842, COX3_ANOGA ;  P33508, COX3_ANOQU ;
DR   P34843, COX3_APILI ;  P92514, COX3_ARATH ;  Q33752, COX3_ARBLI ;
DR   Q33845, COX3_ARTSA ;  Q36309, COX3_ARTSF ;  P24879, COX3_ASCSU ;
DR   Q75G34, COX3_ASHGO ;  Q33824, COX3_ASTPE ;  Q03439, COX3_BACP3 ;
DR   Q04442, COX3_BACPE ;  P24012, COX3_BACSU ;  P69216, COX3_BRAFL ;
DR   P69215, COX3_BRALA ;  P24891, COX3_CAEEL ;  Q9B1P9, COX3_CANAL ;
DR   Q85Q96, COX3_CANGA ;  Q34214, COX3_CANPA ;  Q96133, COX3_CARAU ;
DR   P18945, COX3_CHICK ;  P48872, COX3_CHOCR ;  Q6NGA0, COX3_CORDI ;
DR   Q8FNQ9, COX3_COREF ;  Q9AEL8, COX3_CORGL ;  Q8SEW8, COX3_COTJA ;
DR   P48873, COX3_CYACA ;  P15952, COX3_CYPCA ;  Q9MIY4, COX3_DANRE ;
DR   A9RAG9, COX3_DEBHA ;  Q2LCP9, COX3_DICCI ;  O21049, COX3_DICDI ;
DR   O79552, COX3_DINSE ;  P00417, COX3_DROME ;  P50271, COX3_DROSI ;
DR   P00418, COX3_DROYA ;  P00421, COX3_EMENI ;  Q35242, COX3_ENTDO ;
DR   P34198, COX3_FORLA ;  P55777, COX3_GADMO ;  P32808, COX3_HELAN ;
DR   Q9XLW9, COX3_KLULA ;  O03170, COX3_LATCH ;  P14546, COX3_LEITA ;
DR   P14574, COX3_LOCMI ;  O47475, COX3_LOLBL ;  Q34943, COX3_LUMTE ;
DR   Q95840, COX3_MAGO7 ;  P09138, COX3_MAIZE ;  P26858, COX3_MARPO ;
DR   O47491, COX3_METSE ;  P63857, COX3_MYCBO ;  O69582, COX3_MYCLE ;
DR   Q73YM3, COX3_MYCPA ;  P63856, COX3_MYCTU ;  P41775, COX3_MYTED ;
DR   O63915, COX3_MYXGL ;  P00422, COX3_NEUCR ;  Q5YZ19, COX3_NOCFA ;
DR   P08745, COX3_OENBE ;  P20684, COX3_ONCCL ;  P69217, COX3_ONCMA ;
DR   P48172, COX3_ONCMY ;  P69218, COX3_ONCNE ;  P14852, COX3_ORYSI ;
DR   P06030, COX3_PARDE ;  P12702, COX3_PARLI ;  O79676, COX3_PELSU ;
DR   Q35539, COX3_PETMA ;  P48874, COX3_PICCA ;  P25003, COX3_PISOC ;
DR   Q36675, COX3_PLAVI ;  Q02654, COX3_PODAN ;  Q95914, COX3_POLOR ;
DR   Q37620, COX3_PROWI ;  Q37600, COX3_PYLLI ;  O99822, COX3_RHISA ;
DR   P80441, COX3_RHIST ;  Q1RHH9, COX3_RICBR ;  Q92J29, COX3_RICCN ;
DR   Q4UKK0, COX3_RICFE ;  Q9ZDX3, COX3_RICPR ;  Q9XLX0, COX3_SACKL ;
DR   Q36860, COX3_SALSA ;  P14058, COX3_SCHCO ;  P14575, COX3_SCHPO ;
DR   O79407, COX3_SCYCA ;  P14853, COX3_SOYBN ;  Q35826, COX3_SPOFR ;
DR   Q9ZZ48, COX3_SQUAC ;  Q82AK5, COX3_STRAW ;  O21403, COX3_STRCA ;
DR   Q9X809, COX3_STRCO ;  P15546, COX3_STRPU ;  Q06475, COX3_SYNY3 ;
DR   Q4JQI1, COX3_TETNG ;  Q37679, COX3_THEAN ;  Q36098, COX3_THEPA ;
DR   P50677, COX3_THEVL ;  Q36837, COX3_TRIRU ;  Q37355, COX3_TRYBO ;
DR   Q0H8X4, COX3_USTMA ;  A6H4Q3, COX3_VANPO ;  Q03227, COX3_VICFA ;
DR   P15953, COX3_WHEAT ;  P00419, COX3_XENLA ;  Q9B6D8, COX3_YARLI ;
DR   P00420, COX3_YEAST ;  Q9I8U0, COX41_THUOB;  P80971, COX42_THUOB;
DR   Q03440, COX4_BACP3 ;  Q04452, COX4_BACPE ;  P24013, COX4_BACSU ;
DR   Q6NG99, COX4_CORDI ;  Q8FNQ8, COX4_COREF ;  Q8NNK3, COX4_CORGL ;
DR   P30815, COX4_DICDI ;  P64948, COX4_MYCBO ;  Q9CCF0, COX4_MYCLE ;
DR   Q73YL6, COX4_MYCPA ;  P64947, COX4_MYCTU ;  Q5YZ36, COX4_NOCFA ;
DR   P80327, COX4_ONCMY ;  P77921, COX4_PARDE ;  Q82AK8, COX4_STRAW ;
DR   Q9X812, COX4_STRCO ;  P00424, COX5A_YEAST;  P00425, COX5B_YEAST;
DR   O93980, COX5_ASPNG ;  P06810, COX5_NEUCR ;  O74988, COX5_SCHPO ;
DR   P26310, COX6_DICDI ;  Q9VHS2, COX7A_DROME;  P80979, COX7A_THUOB;
DR   P80334, COX7C_ONCMY;  P80982, COX7C_THUOB;  P10174, COX7_YEAST ;
DR   Q9P4W1, COX8_SCHPO ;  P04039, COX8_YEAST ;  Q757F0, COX9_ASHGO ;
DR   Q6FWE8, COX9_CANGA ;  Q6BPV1, COX9_DEBHA ;  Q6CWK9, COX9_KLULA ;
DR   O94705, COX9_SCHPO ;  P07255, COX9_YEAST ;  P82543, COXA_THET8 ;
DR   P20609, COXE_DICDI ;  P98053, COXM_BRAJA ;  P80981, COXM_THUOB ;
DR   P98000, COXN_BRAJA ;  P80980, COXN_THUOB ;  P20610, COXS_DICDI ;
DR   Q02226, COXT_SOYBN ;  P80333, CX7A1_ONCMY;  P80332, CX7A2_ONCMY;
DR   P98055, FIXN_AGRT7 ;  P98056, FIXN_AZOC5 ;  Q03073, FIXN_BRAJA ;
DR   Q05572, FIXN_RHIME ;
//
ID   1.9.3.2
DE   Transferred entry: 1.7.2.1.
//
ID   1.9.6.1
DE   Nitrate reductase (cytochrome).
CA   2 ferrocytochrome + nitrate + 2 H(+) = 2 ferricytochrome + nitrite.
//
ID   1.9.99.1
DE   Iron--cytochrome-c reductase.
CA   Ferrocytochrome c + Fe(3+) = ferricytochrome c + Fe(2+).
CF   Iron.
//
ID   1.10.1.1
DE   Trans-acenaphthene-1,2-diol dehydrogenase.
CA   (+-)-trans-acenaphthene-1,2-diol + 2 NADP(+) = acenaphthenequinone +
CA   2 NADPH.
CC   -!- Some preparations also utilize NAD(+).
//
ID   1.10.2.1
DE   L-ascorbate--cytochrome-b5 reductase.
CA   L-ascorbate + ferricytochrome b5 = monodehydroascorbate +
CA   ferrocytochrome b5 + H(+).
//
ID   1.10.2.2
DE   Ubiquinol--cytochrome-c reductase.
AN   Complex III (mitochondrial electron transport).
AN   Cytochrome bc1 complex.
AN   Ubiquinone--cytochrome-c oxidoreductase.
CA   QH(2) + 2 ferricytochrome c = Q + 2 ferrocytochrome c + 2 H(+).
CC   -!- Contains cytochrome b-562, cytochrome b-566, cytochrome c1,
CC       and 2-iron ferredoxin.
CC   -!- Depending on the organism and physiological conditions, either two or
CC       four protons are extruded from the cytoplasmic to the non-cytoplasmic
CC       compartment (cf. EC 1.6.99.3).
PR   PROSITE; PDOC00171;
DR   P29677, MPPA_SOLTU ;  P49729, UCRI1_TOBAC;  P51132, UCRI2_TOBAC;
DR   P51133, UCRI3_TOBAC;  P51134, UCRI4_TOBAC;  P51135, UCRI5_TOBAC;
DR   O31214, UCRI_ALLVD ;  Q69BJ9, UCRI_AOTAZ ;  P13272, UCRI_BOVIN ;
DR   P51130, UCRI_BRAJA ;  Q5ZLR5, UCRI_CHICK ;  Q69BK1, UCRI_CHLAE ;
DR   Q69BK0, UCRI_COLPO ;  Q69BK4, UCRI_GORGO ;  P47985, UCRI_HUMAN ;
DR   Q69BJ6, UCRI_HYLSY ;  Q69BJ8, UCRI_LAGLA ;  P49727, UCRI_MAIZE ;
DR   Q9CR68, UCRI_MOUSE ;  P07056, UCRI_NEUCR ;  Q69BK6, UCRI_PANPA ;
DR   Q69BK5, UCRI_PANTR ;  P05417, UCRI_PARDE ;  Q69BK3, UCRI_PONPY ;
DR   P20788, UCRI_RAT   ;  P0CY48, UCRI_RHOCA ;  D5ANZ2, UCRI_RHOCB ;
DR   P23136, UCRI_RHORU ;  Q02762, UCRI_RHOSH ;  P81380, UCRI_RHOVI ;
DR   Q1RIA5, UCRI_RICBR ;  Q92IR2, UCRI_RICCN ;  Q4UKR6, UCRI_RICFE ;
DR   Q9ZDQ5, UCRI_RICPR ;  Q68XA0, UCRI_RICTY ;  Q69BJ7, UCRI_SAISC ;
DR   Q09154, UCRI_SCHPO ;  P37841, UCRI_SOLTU ;  Q69BK2, UCRI_THEGE ;
DR   P08067, UCRI_YEAST ;
//
ID   1.10.3.1
DE   Catechol oxidase.
AN   Diphenol oxidase.
AN   o-diphenolase.
AN   Phenolase.
AN   Polyphenol oxidase.
AN   Tyrosinase.
CA   2 catechol + O(2) = 2 1,2-benzoquinone + 2 H(2)O.
CF   Copper.
CC   -!- Also acts on a variety of substituted catechols.
CC   -!- Many of these enzymes also catalyze the reaction listed under
CC       EC 1.14.18.1; this is especially true for the classical tyrosinase.
PR   PROSITE; PDOC00398;
DR   Q00024, PPO1_AGABI ;  Q9ZP19, PPO1_IPOBA ;  Q9MB14, PPO2_IPOBA ;
DR   Q08303, PPOA_SOLLC ;  Q08304, PPOB_SOLLC ;  Q06355, PPOB_SOLTU ;
DR   Q08305, PPOC_SOLLC ;  Q08306, PPOD_SOLLC ;  Q08307, PPOE_SOLLC ;
DR   Q08296, PPOF_SOLLC ;  P43309, PPO_MALDO  ;  P43310, PPO_SPIOL  ;
DR   Q06215, PPO_VICFA  ;  P43311, PPO_VITVI  ;  P85026, PPO_ZINOF  ;
//
ID   1.10.3.2
DE   Laccase.
AN   Urishiol oxidase.
CA   4 benzenediol + O(2) = 4 benzosemiquinone + 2 H(2)O.
CF   Copper.
CC   -!- A group of multi-copper proteins of low specificity.
CC   -!- Acts on both o- and p-quinols, and often acting also on aminophenols
CC       and phenylenediamine.
CC   -!- The semiquinone may react further either enzymically or non-
CC       enzymically.
PR   PROSITE; PDOC00076;
DR   Q6ID18, LAC10_ARATH;  Q10ND7, LAC10_ORYSJ;  Q8VZA1, LAC11_ARATH;
DR   Q0DHL5, LAC11_ORYSJ;  Q9FLB5, LAC12_ARATH;  Q0DHL2, LAC12_ORYSJ;
DR   Q9LYQ2, LAC13_ARATH;  Q9FY79, LAC14_ARATH;  Q69L99, LAC14_ORYSJ;
DR   Q84J37, LAC15_ARATH;  Q339K6, LAC15_ORYSJ;  Q1PDH6, LAC16_ARATH;
DR   Q7XE50, LAC16_ORYSJ;  Q9FJD5, LAC17_ARATH;  Q2RBK2, LAC17_ORYSJ;
DR   A2XCN6, LAC18_ORYSI;  Q53LU4, LAC18_ORYSJ;  A2Y9C5, LAC19_ORYSI;
DR   Q2R0L2, LAC19_ORYSJ;  P85308, LAC1B_CERUI;  Q12541, LAC1_AGABI ;
DR   Q9LMS3, LAC1_ARATH ;  Q12570, LAC1_BOTFU ;  Q03966, LAC1_CRYPA ;
DR   P17489, LAC1_EMENI ;  P86351, LAC1_GALSP ;  Q70KY3, LAC1_MELAO ;
DR   P06811, LAC1_NEUCR ;  Q5ZCW1, LAC1_ORYSJ ;  Q01679, LAC1_PHLRA ;
DR   Q12729, LAC1_PLEOS ;  O59896, LAC1_PYCCI ;  P56193, LAC1_THACU ;
DR   Q02497, LAC1_TRAHI ;  D0VWU3, LAC1_TRAMX ;  Q99044, LAC1_TRAVI ;
DR   A2Y9C2, LAC20_ORYSI;  Q2R0L0, LAC20_ORYSJ;  Q2QZ80, LAC21_ORYSJ;
DR   Q0IQU1, LAC22_ORYSJ;  Q2QYS3, LAC23_ORYSJ;  Q2QUN2, LAC24_ORYSJ;
DR   Q0IP28, LAC25_ORYSJ;  P85430, LAC2D_CERUI;  Q12542, LAC2_AGABI ;
DR   O81081, LAC2_ARATH ;  Q96WM9, LAC2_BOTFU ;  P85149, LAC2_CERUI ;
DR   Q8RYM9, LAC2_ORYSJ ;  Q12739, LAC2_PLEOS ;  P78722, LAC2_PODAS ;
DR   Q02075, LAC2_THACU ;  Q12718, LAC2_TRAVE ;  Q99046, LAC2_TRAVI ;
DR   Q56YT0, LAC3_ARATH ;  Q96UM2, LAC3_BOTFU ;  Q941X2, LAC3_ORYSJ ;
DR   Q02079, LAC3_THACU ;  Q99049, LAC3_TRAVI ;  O80434, LAC4_ARATH ;
DR   Q5N9X2, LAC4_ORYSJ ;  Q02081, LAC4_THACU ;  Q12719, LAC4_TRAVE ;
DR   Q99055, LAC4_TRAVI ;  Q9SIY8, LAC5_ARATH ;  Q5N9W4, LAC5_ORYSJ ;
DR   Q12717, LAC5_TRAVE ;  Q99056, LAC5_TRAVI ;  Q9ZPY2, LAC6_ARATH ;
DR   Q5N7A3, LAC6_ORYSJ ;  Q9SR40, LAC7_ARATH ;  Q5N7B4, LAC7_ORYSJ ;
DR   Q9LFD2, LAC8_ARATH ;  Q0JHP8, LAC8_ORYSJ ;  Q9LFD1, LAC9_ARATH ;
DR   Q6Z8L2, LAC9_ORYSJ ;  P86328, LACC1_CERUI;  P86327, LACC2_CERUI;
//
ID   1.10.3.3
DE   L-ascorbate oxidase.
AN   Ascorbase.
CA   4 L-ascorbate + O(2) = 4 monodehydroascorbate + 2 H(2)O.
CF   Copper.
PR   PROSITE; PDOC00076;
DR   P24792, ASO_CUCMA  ;  P37064, ASO_CUCPM  ;  P14133, ASO_CUCSA  ;
DR   Q40588, ASO_TOBAC  ;
//
ID   1.10.3.4
DE   o-aminophenol oxidase.
AN   Isophenoxazine synthase.
CA   2 2-aminophenol + O(2) + oxidant = 2-aminophenoxazin-3-one + 2 H(2)O +
CA   reduced oxidant.
CF   Copper or manganese; Flavoprotein.
CC   -!- While the enzyme from the plant Tecoma stans is activated by Mn(2+),
CC       that from the bacterium Streptomyces griseus (GriF) requires Cu(2+)
CC       for maximal activity.
CC   -!- Two molecules of the product 6-iminocyclohexa-2,4-dienone (i.e. 1,2-
CC       benzoquinone monoimine) spontaneously condense with oxidation to
CC       yield 2-aminophenoxazin-3-one.
CC   -!- 3-amino-4-hydroxybenzaldehyde, which has a -CHO group at the para-
CC       position with respect to the hydroxy group of 2-aminophenol,
CC       was found to be the best substrate for GriF.
//
ID   1.10.3.5
DE   3-hydroxyanthranilate oxidase.
AN   3-hydroxyanthranilic acid oxidase.
CA   3-hydroxyanthranilate + O(2) = 6-imino-5-oxocyclohexa-1,3-
CA   dienecarboxylate + H(2)O(2).
//
ID   1.10.3.6
DE   Rifamycin-B oxidase.
CA   Rifamycin B + O(2) = rifamycin O + H(2)O(2).
CC   -!- Also acts on benzene-1,4-diol and, more slowly, on some other
CC       p-quinols.
CC   -!- Not identical with EC 1.10.3.1, EC 1.10.3.2, EC 1.10.3.4 or
CC       EC 1.10.3.5.
//
ID   1.10.3.7
DE   Transferred entry: 1.21.3.4.
//
ID   1.10.3.8
DE   Transferred entry: 1.21.3.5.
//
ID   1.10.3.9
DE   Photosystem II.
CA   2 H(2)O + 2 plastoquinone + 4 light = O(2) + 2 plastoquinol.
CC   -!- Contains chlorophyll a, beta-carotene, pheophytin, plastoquinone,
CC       a Mn(4)Ca cluster, heme and non-heme iron.
CC   -!- Four successive photoreactions, resulting in a storage of four
CC       positive charges, are required to oxidize two water molecules to one
CC       oxygen molecule.
DR   B0CB14, PSBA1_ACAM1;  Q3MCT0, PSBA1_ANAVT;  Q7M7A9, PSBA1_GLOVI;
DR   P46242, PSBA1_NOSS1;  P04996, PSBA1_SYNE7;  P0A445, PSBA1_SYNEN;
DR   Q2JTJ2, PSBA1_SYNJA;  Q2JPR2, PSBA1_SYNJB;  B1XM24, PSBA1_SYNP2;
DR   Q5N5R2, PSBA1_SYNP6;  A5GIM7, PSBA1_SYNPW;  Q7TTJ7, PSBA1_SYNPX;
DR   A5GTY4, PSBA1_SYNR3;  Q0I7J2, PSBA1_SYNS3;  Q3AYB8, PSBA1_SYNS9;
DR   Q3AM89, PSBA1_SYNSC;  P07826, PSBA1_SYNY3;  P0A444, PSBA1_THEEB;
DR   Q11A00, PSBA1_TRIEI;  A5A8K9, PSBA2_ACAM1;  Q3MAB1, PSBA2_ANAVT;
DR   Q7NJX5, PSBA2_GLOVI;  P31694, PSBA2_NOSS1;  P04997, PSBA2_SYNE7;
DR   P0A447, PSBA2_SYNEN;  Q2JTT0, PSBA2_SYNJA;  Q2JP67, PSBA2_SYNJB;
DR   B1XMC3, PSBA2_SYNP2;  Q5N4D2, PSBA2_SYNP6;  A5GJU5, PSBA2_SYNPW;
DR   Q7U669, PSBA2_SYNPX;  A5GTY5, PSBA2_SYNR3;  Q0I912, PSBA2_SYNS3;
DR   Q3AV15, PSBA2_SYNS9;  Q3AKT2, PSBA2_SYNSC;  P16033, PSBA2_SYNY3;
DR   P0A446, PSBA2_THEEB;  Q10VK7, PSBA2_TRIEI;  Q3MB78, PSBA3_ANAVT;
DR   Q7NH81, PSBA3_GLOVI;  Q8YQS7, PSBA3_NOSS1;  Q2JTM8, PSBA3_SYNJA;
DR   B1XIP3, PSBA3_SYNP2;  Q5N337, PSBA3_SYNP6;  Q7U4Z3, PSBA3_SYNPX;
DR   Q0I910, PSBA3_SYNS3;  Q8DIV4, PSBA3_THEEB;  Q3M5L6, PSBA4_ANAVT;
DR   Q3V554, PSBA_ACOCL ;  Q85C23, PSBA_ADICA ;  A4QJ96, PSBA_AETCO ;
DR   A4QJI0, PSBA_AETGR ;  A1E9Y8, PSBA_AGRST ;  Q9TM69, PSBA_ALETA ;
DR   P02956, PSBA_AMAHY ;  Q70Y17, PSBA_AMBTC ;  Q9BBC1, PSBA_AMPCA ;
DR   Q7HP56, PSBA_AMPOP ;  P29270, PSBA_ANAAZ ;  B0YPN1, PSBA_ANEMR ;
DR   A2T309, PSBA_ANGEV ;  Q85BH5, PSBA_ANTFO ;  P24625, PSBA_ANTSP ;
DR   A4QJZ9, PSBA_ARAHI ;  P83755, PSBA_ARATH ;  Q7FNT3, PSBA_ATRBE ;
DR   A4QK85, PSBA_BARVE ;  Q06J41, PSBA_BIGNA ;  P18290, PSBA_BRANA ;
DR   P48265, PSBA_BUMFI ;  A6MM16, PSBA_BUXMI ;  Q7YJY8, PSBA_CALFG ;
DR   A4QKH2, PSBA_CAPBU ;  B1A915, PSBA_CARPA ;  A8SE40, PSBA_CERDE ;
DR   Q8M9W3, PSBA_CHAGL ;  Q1ACM1, PSBA_CHAVU ;  P69565, PSBA_CHERU ;
DR   Q19VC4, PSBA_CHLAT ;  P35860, PSBA_CHLEL ;  P09752, PSBA_CHLMO ;
DR   P07753, PSBA_CHLRE ;  A6MMA2, PSBA_CHLSC ;  P56318, PSBA_CHLVU ;
DR   Q09MJ8, PSBA_CITSI ;  A0A315, PSBA_COFAR ;  Q9T351, PSBA_CONCI ;
DR   Q9TNF8, PSBA_CONSU ;  A4QKR1, PSBA_CRUWA ;  B1VKF9, PSBA_CRYJA ;
DR   Q2QDA8, PSBA_CUCSA ;  A8W3A5, PSBA_CUSEX ;  A7M8Y6, PSBA_CUSGR ;
DR   A8W3H2, PSBA_CUSOB ;  P32036, PSBA_CUSRE ;  P51759, PSBA_CYAA5 ;
DR   O19895, PSBA_CYACA ;  Q85G59, PSBA_CYAME ;  P12719, PSBA_CYAPA ;
DR   A6H5E4, PSBA_CYCTA ;  Q0G9Y2, PSBA_DAUCA ;  A6MMI8, PSBA_DIOEL ;
DR   A4QL00, PSBA_DRANE ;  Q06H17, PSBA_DRIGR ;  Q9TNF7, PSBA_DUMHI ;
DR   P24726, PSBA_ECTSI ;  Q4G3F2, PSBA_EMIHU ;  Q49L18, PSBA_EUCGG ;
DR   P06631, PSBA_EUGGR ;  P07063, PSBA_FREDI ;  P24725, PSBA_GALSU ;
DR   A6BM28, PSBA_GNEPA ;  A0ZZ15, PSBA_GOSBA ;  P69564, PSBA_GOSHI ;
DR   Q6B929, PSBA_GRATL ;  O78446, PSBA_GUITH ;  Q9TJ82, PSBA_GYMMI ;
DR   Q1KXX9, PSBA_HELAN ;  Q32389, PSBA_HETCA ;  Q9MSC0, PSBA_HETNI ;
DR   Q9MSC1, PSBA_HETPY ;  Q9MSC2, PSBA_HETRO ;  Q9XQV1, PSBA_HETTR ;
DR   P05337, PSBA_HORVU ;  Q5SCW8, PSBA_HUPLU ;  A6MMS4, PSBA_ILLOL ;
DR   A7Y395, PSBA_IPOPU ;  Q06RF1, PSBA_JASNU ;  P69557, PSBA_LACSA ;
DR   A9L976, PSBA_LEMMI ;  A6YGB8, PSBA_LEPTE ;  A4QL86, PSBA_LEPVR ;
DR   Q0G9N9, PSBA_LIRTU ;  A4QLH5, PSBA_LOBMA ;  A8Y9F0, PSBA_LOLPR ;
DR   Q9BBU3, PSBA_LOTJA ;  O98736, PSBA_MAGPY ;  P48183, PSBA_MAIZE ;
DR   B1NWD0, PSBA_MANES ;  P06402, PSBA_MARPO ;  Q9S3W5, PSBA_MASLA ;
DR   P04998, PSBA_MEDSA ;  Q9MUW0, PSBA_MESVI ;  P51764, PSBA_MICAE ;
DR   B0JIS8, PSBA_MICAN ;  Q09X37, PSBA_MORIN ;  Q09FY1, PSBA_NANDO ;
DR   A4QLR3, PSBA_NASOF ;  Q9TL35, PSBA_NEPOL ;  P69561, PSBA_NICDE ;
DR   P69562, PSBA_NICPL ;  Q3C1G3, PSBA_NICSY ;  Q33C59, PSBA_NICTO ;
DR   Q6EW68, PSBA_NYMAL ;  P49460, PSBA_ODOSI ;  B0Z4K6, PSBA_OENAR ;
DR   B0Z4U0, PSBA_OENBI ;  P83756, PSBA_OENEH ;  B0Z524, PSBA_OENGL ;
DR   B0Z5A8, PSBA_OENPA ;  A4QJR4, PSBA_OLIPU ;  Q20ET2, PSBA_OLTVI ;
DR   Q6ENJ7, PSBA_ORYNI ;  P0C432, PSBA_ORYSA ;  P0C433, PSBA_ORYSI ;
DR   P0C434, PSBA_ORYSJ ;  Q0P3J1, PSBA_OSTTA ;  O98733, PSBA_PALPL ;
DR   Q68S26, PSBA_PANGI ;  P06585, PSBA_PEA   ;  Q06FY1, PSBA_PELHO ;
DR   P04999, PSBA_PETHY ;  Q3BAR4, PSBA_PHAAO ;  A0T0G9, PSBA_PHATC ;
DR   Q01366, PSBA_PHAVU ;  P50155, PSBA_PICAB ;  P69550, PSBA_PINCO ;
DR   Q85WS3, PSBA_PINKO ;  P69551, PSBA_PINTH ;  Q06GT0, PSBA_PIPCE ;
DR   Q09G66, PSBA_PLAOC ;  Q14FH6, PSBA_POPAL ;  P36491, PSBA_POPDE ;
DR   A4GYN9, PSBA_POPTR ;  P51212, PSBA_PORPU ;  Q1XDS5, PSBA_PORYE ;
DR   P15191, PSBA_PROHO ;  A3PAU3, PSBA_PROM0 ;  A2C057, PSBA_PROM1 ;
DR   A8G5N5, PSBA_PROM2 ;  A2C6Q1, PSBA_PROM3 ;  A2BUK1, PSBA_PROM5 ;
DR   Q31A92, PSBA_PROM9 ;  P46895, PSBA_PROMA ;  Q9TM72, PSBA_PROMC ;
DR   Q7TTH6, PSBA_PROMM ;  Q7V365, PSBA_PROMP ;  A2BP21, PSBA_PROMS ;
DR   Q46JV2, PSBA_PROMT ;  Q3ZJ60, PSBA_PSEAK ;  Q8WI36, PSBA_PSINU ;
DR   A6MVT2, PSBA_RHDSA ;  Q6L3B5, PSBA_SACHY ;  P0C157, PSBA_SACOF ;
DR   Q1KVU8, PSBA_SCEOB ;  P10510, PSBA_SECCE ;  Q2WGI0, PSBA_SELUN ;
DR   P11848, PSBA_SINAL ;  Q2MIK7, PSBA_SOLBU ;  Q2MIC0, PSBA_SOLLC ;
DR   P69563, PSBA_SOLNI ;  Q2VEJ6, PSBA_SOLTU ;  A1E9Q4, PSBA_SORBI ;
DR   P02957, PSBA_SOYBN ;  P27201, PSBA_SPIOG ;  P69560, PSBA_SPIOL ;
DR   Q32RX1, PSBA_STAPU ;  Q06SD2, PSBA_STIHE ;  P14660, PSBA_SYNY4 ;
DR   A0T0W2, PSBA_THAPS ;  P51765, PSBA_THEVL ;  P69556, PSBA_TOBAC ;
DR   P13910, PSBA_VICFA ;  Q33282, PSBA_VIGUN ;  Q0ZJ40, PSBA_VITVI ;
DR   P12463, PSBA_WHEAT ;  Q32RM3, PSBA_ZYGCR ;  B0C1V6, PSBD1_ACAM1;
DR   Q5N3Q7, PSBD1_SYNP6;  B0C3P0, PSBD2_ACAM1;  Q5MZ82, PSBD2_SYNP6;
DR   Q4FFP4, PSBD_ACOAM ;  Q3V539, PSBD_ACOCL ;  Q85FM2, PSBD_ADICA ;
DR   A4QJB0, PSBD_AETCO ;  A4QJJ4, PSBD_AETGR ;  A1E9Z3, PSBD_AGRST ;
DR   Q70Y08, PSBD_AMBTC ;  Q3MA59, PSBD_ANAVT ;  A2T330, PSBD_ANGEV ;
DR   Q85AC9, PSBD_ANTFO ;  P69685, PSBD_ANTMA ;  A4QK13, PSBD_ARAHI ;
DR   P56761, PSBD_ARATH ;  Q8S8X8, PSBD_ATRBE ;  A4QKA0, PSBD_BARVE ;
DR   Q06J67, PSBD_BIGNA ;  Q7Y4H2, PSBD_BPSYP ;  Q6H956, PSBD_BPSYR ;
DR   Q0QZ08, PSBD_BPSYS ;  Q6H952, PSBD_BPSYW ;  B3TNB8, PSBD_BRADI ;
DR   A6MM31, PSBD_BUXMI ;  Q7YJX7, PSBD_CALFG ;  A4QKI7, PSBD_CAPBU ;
DR   B1A930, PSBD_CARPA ;  A8SE98, PSBD_CERDE ;  Q8M9W4, PSBD_CHAGL ;
DR   Q1ACJ7, PSBD_CHAVU ;  Q19VC7, PSBD_CHLAT ;  P06007, PSBD_CHLRE ;
DR   A6MMB7, PSBD_CHLSC ;  P56319, PSBD_CHLVU ;  B5LMM1, PSBD_CICAR ;
DR   Q09MI3, PSBD_CITSI ;  A0A330, PSBD_COFAR ;  A4QKS6, PSBD_CRUWA ;
DR   B1VKH0, PSBD_CRYJA ;  Q4VZN8, PSBD_CUCSA ;  A8W3B9, PSBD_CUSEX ;
DR   A7M8Z6, PSBD_CUSGR ;  A8W3I2, PSBD_CUSOB ;  A7M961, PSBD_CUSRE ;
DR   Q49CA8, PSBD_CUSSA ;  B1WQ89, PSBD_CYAA5 ;  Q9TM47, PSBD_CYACA ;
DR   Q85G27, PSBD_CYAME ;  P48079, PSBD_CYAPA ;  A6H5G6, PSBD_CYCTA ;
DR   Q0G9W7, PSBD_DAUCA ;  A6MMK2, PSBD_DIOEL ;  A4QL14, PSBD_DRANE ;
DR   Q06H02, PSBD_DRIGR ;  Q4G395, PSBD_EMIHU ;  Q49L03, PSBD_EUCGG ;
DR   P31557, PSBD_EUGGR ;  B2XWK0, PSBD_FAGEA ;  P28253, PSBD_GALSU ;
DR   A0ZZ30, PSBD_GOSBA ;  Q2L902, PSBD_GOSHI ;  Q6B918, PSBD_GRATL ;
DR   B2LMI8, PSBD_GUIAB ;  O78427, PSBD_GUITH ;  Q1KXW4, PSBD_HELAN ;
DR   B2XT21, PSBD_HETA2 ;  B2XTH7, PSBD_HETA4 ;  P11849, PSBD_HORVU ;
DR   A6MMT9, PSBD_ILLOL ;  A7Y3C4, PSBD_IPOPU ;  Q06RD6, PSBD_JASNU ;
DR   Q56P05, PSBD_LACSA ;  A9L991, PSBD_LEMMI ;  A6YG76, PSBD_LEPTE ;
DR   A4QLA1, PSBD_LEPVR ;  Q0G9M4, PSBD_LIRTU ;  A4QLI9, PSBD_LOBMA ;
DR   A8Y9F5, PSBD_LOLPR ;  Q9BBT0, PSBD_LOTJA ;  P48184, PSBD_MAIZE ;
DR   B1NWE5, PSBD_MANES ;  P06404, PSBD_MARPO ;  Q9MUW2, PSBD_MESVI ;
DR   Q09X22, PSBD_MORIN ;  Q09FW6, PSBD_NANDO ;  A4QLS8, PSBD_NASOF ;
DR   Q9TL00, PSBD_NEPOL ;  Q3C1I4, PSBD_NICSY ;  Q33C42, PSBD_NICTO ;
DR   B2IVV1, PSBD_NOSP7 ;  Q8XFA5, PSBD_NOSS1 ;  Q4FFP2, PSBD_NUPAD ;
DR   Q6EW53, PSBD_NYMAL ;  P49478, PSBD_ODOSI ;  B0Z4M2, PSBD_OENAR ;
DR   B0Z4V6, PSBD_OENBI ;  Q9MTN1, PSBD_OENEH ;  B0Z540, PSBD_OENGL ;
DR   B0Z5C4, PSBD_OENPA ;  A4QJS8, PSBD_OLIPU ;  Q20EU7, PSBD_OLTVI ;
DR   Q6ENJ1, PSBD_ORYNI ;  P0C435, PSBD_ORYSA ;  P0C436, PSBD_ORYSI ;
DR   P0C437, PSBD_ORYSJ ;  Q0P3Q0, PSBD_OSTTA ;  Q68S11, PSBD_PANGI ;
DR   B1X3H4, PSBD_PAUCH ;  P06006, PSBD_PEA   ;  Q06FW1, PSBD_PELHO ;
DR   Q3BAP5, PSBD_PHAAO ;  A0T097, PSBD_PHATC ;  A4GGA2, PSBD_PHAVU ;
DR   Q6YXN8, PSBD_PHYPA ;  Q85WW5, PSBD_PINKO ;  P41644, PSBD_PINTH ;
DR   Q06GR5, PSBD_PIPCE ;  Q09G51, PSBD_PLAOC ;  Q14FG2, PSBD_POPAL ;
DR   Q9XQA8, PSBD_POPDE ;  A4GYQ4, PSBD_POPTR ;  P51357, PSBD_PORPU ;
DR   Q1XDD0, PSBD_PORYE ;  P51766, PSBD_PROHO ;  Q7V6I0, PSBD_PROMM ;
DR   Q3ZJ46, PSBD_PSEAK ;  Q8WI19, PSBD_PSINU ;  Q4FFP1, PSBD_RANMC ;
DR   Q6L3B1, PSBD_SACHY ;  Q6ENY1, PSBD_SACOF ;  Q1KVW6, PSBD_SCEOB ;
DR   P10803, PSBD_SECCE ;  Q2MIJ2, PSBD_SOLBU ;  Q2MIA5, PSBD_SOLLC ;
DR   Q2VEI1, PSBD_SOLTU ;  A1E9Q9, PSBD_SORBI ;  Q2PMT8, PSBD_SOYBN ;
DR   P06005, PSBD_SPIOL ;  Q32RT0, PSBD_STAPU ;  Q06SH5, PSBD_STIHE ;
DR   P11005, PSBD_SYNE7 ;  Q2JRJ5, PSBD_SYNJA ;  Q2JKT8, PSBD_SYNJB ;
DR   P20898, PSBD_SYNP2 ;  A5GMA8, PSBD_SYNPW ;  Q7TTI2, PSBD_SYNPX ;
DR   A5GQK3, PSBD_SYNR3 ;  Q0I6Z7, PSBD_SYNS3 ;  Q3B038, PSBD_SYNS9 ;
DR   Q3AH25, PSBD_SYNSC ;  P09192, PSBD_SYNY3 ;  A0T0T0, PSBD_THAPS ;
DR   Q8CM25, PSBD_THEEB ;  P69686, PSBD_TOBAC ;  Q116J3, PSBD_TRIEI ;
DR   Q0ZJ25, PSBD_VITVI ;  B2Y1U5, PSBD_WELMI ;  Q36814, PSBD_WHEAT ;
DR   Q32RM5, PSBD_ZYGCR ;
//
ID   1.10.3.10
DE   Ubiquinol oxidase (H(+)-transporting).
AN   Cytochrome bb3 oxidase.
AN   Cytochrome bd-I oxidase.
AN   Cytochrome bo oxidase.
CA   2 ubiquinol + O(2) + n H(+)(In) = 2 ubiquinone + 2 H(2)O + n H(+)(Out).
CF   Copper; Heme.
CC   -!- Contains a dinuclear center comprising two hemes, or heme and copper.
CC   -!- Reduction of O(2) on the periplasmic side of the membrane leads to
CC       release of protons in the periplasm, generating a transmembrane
CC       proton gradient.
CC   -!- In addition, the bb3 and bo oxidases, but not the bd oxidase,
CC       contribute to the proton gradient by actively pumping protons across
CC       the membrane.
//
ID   1.10.3.11
DE   Ubiquinol oxidase.
AN   Cyanide-insensitive oxidase.
AN   Cytochrome bd-II oxidase.
AN   Plant alternative oxidase.
CA   2 ubiquinol + O(2) = 2 ubiquinone + 2 H(2)O.
CF   Iron or heme.
CC   -!- The enzyme in mitochondria from thermogenic tissues of plants and
CC       from certain protists contains a dinuclear iron complex.
CC   -!- Cytochrome bd-II from Escherichia coli contains a diheme active site.
//
ID   1.10.3.12
DE   Menaquinol oxidase (H(+)-transporting).
AN   Cytochrome aa3-600 oxidase.
AN   Cytochrome bd oxidase.
CA   2 menaquinol + O(2) = 2 menaquinone + 2 H(2)O.
CF   Copper; Heme.
CC   -!- Cytochrome aa3-600, one of the principal respiratory oxidases from
CC       Bacillus subtilis, is a member of the heme-copper superfamily of
CC       oxygen reductases, and is a close homolog of the cytochrome bo3
CC       ubiquinol oxidase from Escherichia coli, but uses menaquinol instead
CC       of ubiquinol as a substrate.
CC   -!- The enzyme also pumps protons across the membrane bilayer, generating
CC       a proton motive force.
//
ID   1.10.99.1
DE   Plastoquinol--plastocyanin reductase.
AN   Cytochrome b6f complex.
CA   Plastoquinol-1 + 2 oxidized plastocyanin = plastoquinone +
CA   2 reduced plastocyanin.
CC   -!- A cytochrome f,b6 complex separated from chloroplasts.
CC   -!- Also acts, more slowly, on plastoquinol-9 and ubiquinols.
CC   -!- Cytochrome c-552 can act instead of plastocyanin, but more slowly.
DR   Q9L3P9, UCRIA_ANAVT;  Q9ZR03, UCRIA_ARATH;  Q7XYM4, UCRIA_BIGNA;
DR   P49728, UCRIA_CHLRE;  Q5CC93, UCRIA_CYAPA;  O49078, UCRIA_FRIAG;
DR   Q93SX0, UCRIA_NOSS1;  Q69S39, UCRIA_ORYSJ;  P26291, UCRIA_PEA  ;
DR   Q69GY7, UCRIA_SOLTU;  P08980, UCRIA_SPIOL;  P74714, UCRIA_SYNY3;
DR   P30361, UCRIA_TOBAC;  Q9SBN3, UCRIA_VOLCA;  Q7X9A6, UCRIA_WHEAT;
DR   Q93SW6, UCRIB_ANAVT;  Q5CC92, UCRIB_CYAPA;  Q93SW8, UCRIB_NOSS1;
DR   P26290, UCRIB_SYNY3;  Q02585, UCRIB_TOBAC;  P70758, UCRIC_NOSS1;
DR   Q46136, UCRI_CHLLT ;  Q9F722, UCRI_CHLTE ;  B8HNR1, UCRI_CYAP4 ;
DR   Q7NCE1, UCRI_GLOVI ;  P83794, UCRI_MASLA ;  B0JXB7, UCRI_MICAN ;
DR   B2J3K2, UCRI_NOSP7 ;  P14698, UCRI_NOSSP ;  A3PBI5, UCRI_PROM0 ;
DR   A2C0R9, UCRI_PROM1 ;  A8G3H7, UCRI_PROM2 ;  A2C7F6, UCRI_PROM3 ;
DR   A9BE84, UCRI_PROM4 ;  A2BVC4, UCRI_PROM5 ;  Q31C72, UCRI_PROM9 ;
DR   Q7VDC0, UCRI_PROMA ;  Q7V654, UCRI_PROMM ;  Q7V2L4, UCRI_PROMP ;
DR   A2BPU5, UCRI_PROMS ;  Q46GW1, UCRI_PROMT ;  Q31NV7, UCRI_SYNE7 ;
DR   P0C8N7, UCRI_SYNEL ;  Q2JUP1, UCRI_SYNJA ;  Q2JL39, UCRI_SYNJB ;
DR   P26292, UCRI_SYNP2 ;  Q5N5B0, UCRI_SYNP6 ;  A5GMW1, UCRI_SYNPW ;
DR   Q7U566, UCRI_SYNPX ;  A5GRU8, UCRI_SYNR3 ;  Q0I872, UCRI_SYNS3 ;
DR   Q3AWL7, UCRI_SYNS9 ;  Q3ALY0, UCRI_SYNSC ;  P0C8N8, UCRI_THEEB ;
DR   Q114L6, UCRI_TRIEI ;
//
ID   1.10.99.2
DE   Ribosyldihydronicotinamide dehydrogenase (quinone).
AN   N-ribosyldihydronicotinamide dehydrogenase (quinone).
AN   NAD(P)H:quinone oxidoreductase 2.
AN   NQO(2).
AN   NRH:quinone oxidoreductase 2.
AN   QR2.
AN   Quinone reductase 2.
CA   1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D-
CA   ribofuranosyl)nicotinamide + a hydroquinone.
CF   FAD; Zinc.
CC   -!- Unlike EC 1.6.5.2, this quinone reductase cannot use NADH or NADPH;
CC       instead it uses N-ribosyl- and N-alkyldihydronicotinamides.
CC   -!- Polycyclic aromatic hydrocarbons, such as benz[a]anthracene, and the
CC       estrogens 17-beta-estradiol and diethylstilbestrol are potent
CC       inhibitors, but dicoumarol is only a very weak inhibitor.
CC   -!- This enzyme can catalyze both 2-electron and 4-electron reductions,
CC       but one-electron acceptors, such as potassium ferricyanide, cannot be
CC       reduced.
DR   P16083, NQO2_HUMAN ;  Q9JI75, NQO2_MOUSE ;  Q5RBB9, NQO2_PONAB ;
DR   Q6AY80, NQO2_RAT   ;
//
ID   1.10.99.3
DE   Violaxanthin de-epoxidase.
AN   VDE.
CA   (1) Violaxanthin + ascorbate = antheraxanthin + dehydroascorbate + H(2)O.
CA   (2) Antheraxanthin + ascorbate = zeaxanthin + dehydroascorbate + H(2)O.
CC   -!- Along with EC 1.14.13.90, this enzyme forms part of the xanthophyll
CC       (or violaxanthin) cycle for controlling the concentration of
CC       zeaxanthin in chloroplasts.
CC   -!- It is activated by a low pH of the thylakoid lumen (produced by high
CC       light intensity).
CC   -!- Zeaxanthin induces the dissipation of excitation energy in the
CC       chlorophyll of the light-harvesting protein complex of photosystem
CC       II.
CC   -!- In higher plants the enzyme reacts with all-trans-diepoxides, such as
CC       violaxanthin, and all-trans-monoepoxides, but in the alga Mantoniella
CC       squamata, only the diepoxides are good substrates.
DR   Q39249, VDE_ARATH  ;  Q40251, VDE_LACSA  ;  Q9SM43, VDE_SPIOL  ;
DR   Q40593, VDE_TOBAC  ;
//
ID   1.11.1.1
DE   NADH peroxidase.
CA   NADH + H(2)O(2) = NAD(+) + 2 H(2)O.
CF   FAD.
CC   -!- Ferricyanide, quinones, etc., can replace H(2)O(2).
DR   P37062, NAPE_ENTFA ;  Q97D82, RRBR1_CLOAB;  Q97D83, RRBR2_CLOAB;
DR   Q97FZ9, RUBY1_CLOAB;  Q97ET8, RUBY2_CLOAB;
//
ID   1.11.1.2
DE   NADPH peroxidase.
CA   NADPH + H(2)O(2) = NADP(+) + 2 H(2)O.
//
ID   1.11.1.3
DE   Fatty-acid peroxidase.
CA   Palmitate + 2 H(2)O(2) = pentadecanal + CO(2) + 3 H(2)O.
CC   -!- Acts on long-chain fatty acids from dodecanoic to octadecanoic acid.
//
ID   1.11.1.4
DE   Transferred entry: 1.13.11.11.
//
ID   1.11.1.5
DE   Cytochrome-c peroxidase.
CA   2 ferrocytochrome c + H(2)O(2) = 2 ferricytochrome c + 2 H(2)O.
CF   Heme.
PR   PROSITE; PDOC00394;
DR   Q6CAB5, CCPR2_YARLI;  Q4WPF8, CCPR_ASPFU ;  Q5AEN1, CCPR_CANAL ;
DR   Q6FMG7, CCPR_CANGA ;  P0CP55, CCPR_CRYNB ;  P0CP54, CCPR_CRYNJ ;
DR   Q6URB0, CCPR_CRYNV ;  Q6BKY9, CCPR_DEBHA ;  P0C0V3, CCPR_EMENI ;
DR   Q4ING3, CCPR_GIBZE ;  Q6CW24, CCPR_KLULA ;  A4QVH4, CCPR_MAGO7 ;
DR   Q7SDV9, CCPR_NEUCR ;  P55929, CCPR_NITEU ;  P14532, CCPR_PSEAE ;
DR   Q4PBY6, CCPR_USTMA ;  Q6C0Z6, CCPR_YARLI ;  P00431, CCPR_YEAST ;
DR   P37197, YHJA_ECOLI ;
//
ID   1.11.1.6
DE   Catalase.
CA   2 H(2)O(2) = O(2) + 2 H(2)O.
CF   Heme; Manganese.
CC   -!- This enzyme can also act as an EC 1.11.1.7 for which several organic
CC       substances, especially ethanol, can act as a hydrogen donor.
CC   -!- A manganese protein containing Mn(3+) in the resting state, which
CC       also belongs here, is often called pseudocatalase.
CC   -!- Enzymes from some microorganisms, such as Penicillium simplicissimum,
CC       which exhibit both catalase and peroxidase activity, have sometimes
CC       been referred to as catalase-peroxidase.
PR   PROSITE; PDOC00395;
DR   P83657, CAT1_COMTR ;  Q9C168, CAT1_NEUCR ;  P81138, CAT1_PENJA ;
DR   Q9C169, CAT3_NEUCR ;  Q96528, CATA1_ARATH;  Q27487, CATA1_CAEEL;
DR   P48350, CATA1_CUCPE;  P17598, CATA1_GOSHI;  P55307, CATA1_HORVU;
DR   P18122, CATA1_MAIZE;  P49315, CATA1_NICPL;  P0C549, CATA1_ORYSI;
DR   Q0E4K1, CATA1_ORYSJ;  Q01297, CATA1_RICCO;  P30264, CATA1_SOLLC;
DR   P49284, CATA1_SOLTU;  P29756, CATA1_SOYBN;  P49319, CATA1_TOBAC;
DR   Q43206, CATA1_WHEAT;  P25819, CATA2_ARATH;  O61235, CATA2_CAEEL;
DR   P48351, CATA2_CUCPE;  P30567, CATA2_GOSHI;  P55308, CATA2_HORVU;
DR   P12365, CATA2_MAIZE;  P49316, CATA2_NICPL;  A2YH64, CATA2_ORYSI;
DR   Q0D9C4, CATA2_ORYSJ;  P49318, CATA2_RICCO;  Q9XHH3, CATA2_SOLLC;
DR   P55312, CATA2_SOLTU;  P55313, CATA2_WHEAT;  Q42547, CATA3_ARATH;
DR   P48352, CATA3_CUCPE;  P18123, CATA3_MAIZE;  P49317, CATA3_NICPL;
DR   O48560, CATA3_SOYBN;  O48561, CATA4_SOYBN;  P90682, CATA_ASCSU ;
DR   P78574, CATA_ASPFU ;  Q9AXH0, CATA_AVIMR ;  P45737, CATA_BACFR ;
DR   P26901, CATA_BACSU ;  P0A324, CATA_BORBR ;  P0A325, CATA_BORPA ;
DR   P0A323, CATA_BORPE ;  P55304, CATA_BOTFU ;  P00432, CATA_BOVIN ;
DR   P0A327, CATA_BRUAB ;  P0A326, CATA_BRUME ;  Q8FWU0, CATA_BRUSU ;
DR   Q2I6W4, CATA_CALJA ;  Q59296, CATA_CAMJE ;  O13289, CATA_CANAL ;
DR   Q96VB8, CATA_CANBO ;  O97492, CATA_CANFA ;  P07820, CATA_CANTR ;
DR   Q9M5L6, CATA_CAPAN ;  Q64405, CATA_CAVPO ;  Q9PT92, CATA_DANRE ;
DR   Q59337, CATA_DEIRA ;  Q9ZN99, CATA_DESVM ;  O77229, CATA_DICDI ;
DR   P17336, CATA_DROME ;  P55305, CATA_EMENI ;  Q8X1P0, CATA_ERYGR ;
DR   Q9PWF7, CATA_GLARU ;  P44390, CATA_HAEIN ;  P45739, CATA_HELAN ;
DR   Q9ZKX5, CATA_HELPJ ;  P77872, CATA_HELPY ;  P04040, CATA_HUMAN ;
DR   P07145, CATA_IPOBA ;  P30265, CATA_LACSK ;  Q926X0, CATA_LISIN ;
DR   Q8Y3P9, CATA_LISMO ;  P24168, CATA_LISSE ;  O93662, CATA_METBF ;
DR   P29422, CATA_MICLU ;  P24270, CATA_MOUSE ;  Q59602, CATA_NEIGO ;
DR   Q27710, CATA_ONCVE ;  P25890, CATA_PEA   ;  P11934, CATA_PENJA ;
DR   P30263, CATA_PICAN ;  O62839, CATA_PIG   ;  Q5RF10, CATA_PONAB ;
DR   P42321, CATA_PROMI ;  O52762, CATA_PSEAE ;  Q59714, CATA_PSEPU ;
DR   P04762, CATA_RAT   ;  P95631, CATA_RHIME ;  P55306, CATA_SCHPO ;
DR   P55310, CATA_SECCE ;  O24339, CATA_SOLAP ;  P55311, CATA_SOLME ;
DR   Q2FH99, CATA_STAA3 ;  Q2FYU7, CATA_STAA8 ;  Q2YXT2, CATA_STAAB ;
DR   Q5HG86, CATA_STAAC ;  Q99UE2, CATA_STAAM ;  Q7A5T2, CATA_STAAN ;
DR   Q6GH72, CATA_STAAR ;  Q6G9M4, CATA_STAAS ;  Q9L4S1, CATA_STAAU ;
DR   Q8NWV5, CATA_STAAW ;  Q2PUJ9, CATA_STAEP ;  Q5HPK8, CATA_STAEQ ;
DR   Q8CPD0, CATA_STAES ;  Q4L643, CATA_STAHJ ;  Q49XC1, CATA_STAS1 ;
DR   Q9KW19, CATA_STAWA ;  Q9EV50, CATA_STAXY ;  Q9Z598, CATA_STRCO ;
DR   Q9XZD5, CATA_TOXGO ;  Q9KRQ1, CATA_VIBCH ;  O68146, CATA_VIBF1 ;
DR   Q87JE8, CATA_VIBPA ;  Q8D452, CATA_VIBVU ;  Q7MFM6, CATA_VIBVY ;
DR   P32290, CATA_VIGRR ;  P15202, CATA_YEAST ;  Q9Y7C2, CATB_AJECA ;
DR   Q92405, CATB_ASPFU ;  Q877A8, CATB_ASPOR ;  Q55DH8, CATB_DICDI ;
DR   P78619, CATB_EMENI ;  Q59635, CATB_PSEAE ;  P46206, CATB_PSESY ;
DR   Q66V81, CATB_STAXY ;  P30266, CATE_BACPE ;  P42234, CATE_BACSU ;
DR   P21179, CATE_ECOLI ;  P50979, CATE_MYCAV ;  Q9I1W8, CATE_PSEAE ;
DR   P95539, CATE_PSEPU ;  Q9X576, CATE_RHIME ;  P55303, CATR_ASPNG ;
DR   A6ZV70, CATT_YEAS7 ;  P06115, CATT_YEAST ;  P94377, CATX_BACSU ;
DR   P80878, MCAT_BACSU ;  Q97FE0, MCAT_CLOAB ;  P60355, MCAT_LACPL ;
//
ID   1.11.1.7
DE   Peroxidase.
AN   Lactoperoxidase.
CA   2 phenolic donor + H(2)O(2) = 2 phenoxyl radical of the donor + 2 H(2)O.
CF   Heme.
PR   PROSITE; PDOC00394;
DR   Q55080, CP119_SULAC;  C0IW58, LNP_TAICA  ;  Q23490, MLT7_CAEEL ;
DR   Q9FX85, PER10_ARATH;  P86067, PER10_DAUCA;  Q96519, PER11_ARATH;
DR   Q96520, PER12_ARATH;  O49293, PER13_ARATH;  Q9SI17, PER14_ARATH;
DR   Q9SI16, PER15_ARATH;  Q9LEH3, PER15_IPOBA;  Q96518, PER16_ARATH;
DR   Q9SJZ2, PER17_ARATH;  Q9SK52, PER18_ARATH;  O22959, PER19_ARATH;
DR   P00433, PER1A_ARMRU;  P15232, PER1B_ARMRU;  P15233, PER1C_ARMRU;
DR   P22195, PER1_ARAHY ;  Q96506, PER1_ARATH ;  P85331, PER1_BETPN ;
DR   P85999, PER1_CAPAN ;  P85439, PER1_CATRO ;  P85346, PER1_CYCRE ;
DR   P86054, PER1_DAUCA ;  P27337, PER1_HORVU ;  A5H8G4, PER1_MAIZE ;
DR   P37834, PER1_ORYSJ ;  P15003, PER1_SOLLC ;  P84516, PER1_SORBI ;
DR   P86103, PER1_VITRO ;  P86014, PER1_VITVI ;  Q05855, PER1_WHEAT ;
DR   Q4W1I8, PER1_ZINEL ;  Q9SLH7, PER20_ARATH;  Q42580, PER21_ARATH;
DR   P24102, PER22_ARATH;  O80912, PER23_ARATH;  Q9ZV04, PER24_ARATH;
DR   O80822, PER25_ARATH;  O22862, PER26_ARATH;  Q43735, PER27_ARATH;
DR   Q9SS67, PER28_ARATH;  Q9LSP0, PER29_ARATH;  P22196, PER2_ARAHY ;
DR   P17179, PER2_ARMRU ;  P85333, PER2_BETPN ;  P86000, PER2_CAPAN ;
DR   P19135, PER2_CUCSA ;  P85347, PER2_CYCRE ;  P86055, PER2_DAUCA ;
DR   Q01548, PER2_HORVU ;  Q9FEQ8, PER2_MAIZE ;  A2YPX3, PER2_ORYSI ;
DR   Q0D3N0, PER2_ORYSJ ;  P15004, PER2_SOLLC ;  P85994, PER2_VITVI ;
DR   Q4W1I9, PER2_ZINEL ;  Q9LSY7, PER30_ARATH;  Q9LHA7, PER31_ARATH;
DR   Q9LHB9, PER32_ARATH;  P24101, PER33_ARATH;  Q9SMU8, PER34_ARATH;
DR   Q96510, PER35_ARATH;  Q9SD46, PER36_ARATH;  Q9LDN9, PER37_ARATH;
DR   Q9LDA4, PER38_ARATH;  Q9SUT2, PER39_ARATH;  O23044, PER3_ARATH ;
DR   P17180, PER3_ARMRU ;  P85334, PER3_BETPN ;  P86001, PER3_CAPAN ;
DR   P85348, PER3_CYCRE ;  P86056, PER3_DAUCA ;  P85996, PER3_SOLLC ;
DR   P86015, PER3_VITVI ;  O23474, PER40_ARATH;  O23609, PER41_ARATH;
DR   Q9SB81, PER42_ARATH;  A5H453, PER42_MAIZE;  Q9SZH2, PER43_ARATH;
DR   Q93V93, PER44_ARATH;  Q96522, PER45_ARATH;  O81772, PER46_ARATH;
DR   Q9SZB9, PER47_ARATH;  O81755, PER48_ARATH;  O23237, PER49_ARATH;
DR   Q9LE15, PER4_ARATH ;  P85335, PER4_BETPN ;  P86002, PER4_CAPAN ;
DR   P85349, PER4_CYCRE ;  P86057, PER4_DAUCA ;  P85998, PER4_SOLLC ;
DR   A7NY33, PER4_VITVI ;  Q43731, PER50_ARATH;  Q9SZE7, PER51_ARATH;
DR   Q9FLC0, PER52_ARATH;  Q42578, PER53_ARATH;  Q9FG34, PER54_ARATH;
DR   Q96509, PER55_ARATH;  Q9LXG3, PER56_ARATH;  Q43729, PER57_ARATH;
DR   P59120, PER58_ARATH;  Q39034, PER59_ARATH;  Q9M9Q9, PER5_ARATH ;
DR   P85351, PER5_BETPN ;  P86003, PER5_CAPAN ;  P85431, PER5_CYCRE ;
DR   P86058, PER5_DAUCA ;  A7QEU4, PER5_VITVI ;  Q9FMR0, PER60_ARATH;
DR   Q9FLV5, PER61_ARATH;  Q9FKA4, PER62_ARATH;  Q9FL16, PER63_ARATH;
DR   Q43872, PER64_ARATH;  Q9FJR1, PER65_ARATH;  Q9LT91, PER66_ARATH;
DR   A5H454, PER66_MAIZE;  Q9LVL2, PER67_ARATH;  Q9LVL1, PER68_ARATH;
DR   Q96511, PER69_ARATH;  O48677, PER6_ARATH ;  P86004, PER6_CAPAN ;
DR   P85432, PER6_CYCRE ;  P86062, PER6_DAUCA ;  P85995, PER6_VITVI ;
DR   Q9FMI7, PER70_ARATH;  A5H452, PER70_MAIZE;  Q43387, PER71_ARATH;
DR   Q9FJZ9, PER72_ARATH;  Q43873, PER73_ARATH;  Q9SY33, PER7_ARATH ;
DR   P86006, PER7_CAPAN ;  P85433, PER7_CYCRE ;  P86063, PER7_DAUCA ;
DR   Q9LNL0, PER8_ARATH ;  P86007, PER8_CAPAN ;  P85434, PER8_CYCRE ;
DR   P86064, PER8_DAUCA ;  Q96512, PER9_ARATH ;  P86008, PER9_CAPAN ;
DR   P85976, PER9_CYCRE ;  P86066, PER9_DAUCA ;  P80679, PERA2_ARMRU;
DR   P84752, PERA_ALOVR ;  O04795, PERA_IPOBA ;  P84753, PERB_ALOVR ;
DR   P82600, PERC_AEDAE ;  Q7QH73, PERC_ANOGA ;  P85332, PERC_BETPN ;
DR   Q9VEG6, PERC_DROME ;  P59121, PERE5_ARMRU;  P11678, PERE_HUMAN ;
DR   P49290, PERE_MOUSE ;  P80550, PERE_PIG   ;  P80025, PERL_BOVIN ;
DR   P22079, PERL_HUMAN ;  Q9XIV8, PERN1_TOBAC;  Q42517, PERN_ARMRU ;
DR   O04796, PERN_IPOBA ;  Q01603, PERO_DROME ;  P00434, PERP7_BRARA;
DR   P16147, PERX_LUPPO ;  Q02200, PERX_NICSY ;  P12437, PERX_SOLTU ;
DR   P11965, PERX_TOBAC ;  P15984, PERX_WHEAT ;  P28313, PER_ARTRA  ;
DR   A8NK72, PER_COPC7  ;  P28314, PER_COPCI  ;  P84714, PER_CYNSC  ;
DR   P85317, PER_GINBI  ;  P85957, PER_PSEMZ  ;  Q6TMK4, POXA_DICDI ;
DR   Q9SCX8, PPA17_ARATH;  Q949Y3, PPA26_ARATH;  O77834, PRDX6_BOVIN;
DR   P30041, PRDX6_HUMAN;  P86215, PRDX6_MESAU;  O08709, PRDX6_MOUSE;
DR   Q9TSX9, PRDX6_PIG  ;  O35244, PRDX6_RAT  ;  A1KZ92, PXDNL_HUMAN;
DR   A8WQH2, PXDN_CAEBR ;  Q1ENI8, PXDN_CAEEL ;  Q9VZZ4, PXDN_DROME ;
DR   Q92626, PXDN_HUMAN ;  Q3UQ28, PXDN_MOUSE ;  A4IGL7, PXDN_XENTR ;
//
ID   1.11.1.8
DE   Iodide peroxidase.
AN   Iodinase.
AN   Iodotyrosine deiodase.
AN   Iodotyrosine deiodinase.
AN   Thyroid peroxidase.
AN   Thyroperoxidase.
AN   TPO.
CA   2 iodide + H(2)O(2) + 2 H(+) = 2 iodine + 2 H(2)O.
CF   Heme.
PR   PROSITE; PDOC00394;
DR   Q8HYB7, PERT_CANFA ;  P07202, PERT_HUMAN ;  P35419, PERT_MOUSE ;
DR   P09933, PERT_PIG   ;  P14650, PERT_RAT   ;
//
ID   1.11.1.9
DE   Glutathione peroxidase.
CA   2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O.
CF   Selenium.
CC   -!- Steroid and lipid hydroperoxides, but not the product of reaction of
CC       EC 1.13.11.12 on phospholipids, can act as acceptor, but more slowly
CC       than H(2)O(2) (cf. EC 1.11.1.12).
PR   PROSITE; PDOC00396;
DR   Q9CFV1, GPO_LACLA  ;  O32770, GPO_LACLM  ;  P74250, GPO_SYNY3  ;
DR   O08368, GPWA_PSEWI ;  P00435, GPX1_BOVIN ;  O02621, GPX1_CAEEL ;
DR   Q0EF99, GPX1_CALJA ;  Q4AEI1, GPX1_CEBAP ;  P83564, GPX1_CHLRE ;
DR   O23970, GPX1_HELAN ;  P07203, GPX1_HUMAN ;  Q4AEI2, GPX1_HYLLA ;
DR   Q865R2, GPX1_MACFU ;  P11352, GPX1_MOUSE ;  Q0EFA0, GPX1_PANTR ;
DR   Q8MJ14, GPX1_PIG   ;  Q4AEI3, GPX1_PONPY ;  P11909, GPX1_RABIT ;
DR   P04041, GPX1_RAT   ;  Q00277, GPX1_SCHMA ;  O59858, GPX1_SCHPO ;
DR   P36014, GPX1_YEAST ;  O04922, GPX2_ARATH ;  O62327, GPX2_CAEEL ;
DR   Q0EF98, GPX2_CALJA ;  Q4AEH7, GPX2_CEBAP ;  P18283, GPX2_HUMAN ;
DR   Q4AEH9, GPX2_HYLLA ;  Q4AEH8, GPX2_MACFU ;  Q9JHC0, GPX2_MOUSE ;
DR   Q4AEI0, GPX2_PONPY ;  P83645, GPX2_RAT   ;  P38143, GPX2_YEAST ;
DR   O22850, GPX3_ARATH ;  P37141, GPX3_BOVIN ;  Q95003, GPX3_CAEEL ;
DR   Q4AEH3, GPX3_CEBAP ;  P22352, GPX3_HUMAN ;  Q4AEH5, GPX3_HYLLA ;
DR   Q4AEH4, GPX3_MACFU ;  P46412, GPX3_MOUSE ;  Q5RFG3, GPX3_PONPY ;
DR   P23764, GPX3_RAT   ;  Q8L910, GPX4_ARATH ;  P81087, GPX4_PINPS ;
DR   Q9LYB4, GPX5_ARATH ;  O46607, GPX5_CANFA ;  O75715, GPX5_HUMAN ;
DR   P28714, GPX5_MACFA ;  P21765, GPX5_MOUSE ;  O18994, GPX5_PIG   ;
DR   P30710, GPX5_RAT   ;  P59796, GPX6_HUMAN ;  Q91WR8, GPX6_MOUSE ;
DR   Q64625, GPX6_RAT   ;  Q9SZ54, GPX7_ARATH ;  A6QLY2, GPX7_BOVIN ;
DR   Q96SL4, GPX7_HUMAN ;  Q99LJ6, GPX7_MOUSE ;  Q6IRC8, GPX8A_XENLA;
DR   Q5U583, GPX8B_XENLA;  Q8LBU2, GPX8_ARATH ;  Q2NL01, GPX8_BOVIN ;
DR   Q7ZV14, GPX8_DANRE ;  Q8TED1, GPX8_HUMAN ;  Q9D7B7, GPX8_MOUSE ;
DR   Q4RSM6, GPX8_TETNG ;  P67877, GPXC_BRUMA ;  P67878, GPXC_BRUPA ;
DR   P52033, GPXC_DIRIM ;  P35666, GPXC_WUCBA ;  Q98234, GPX_MCV1   ;
//
ID   1.11.1.10
DE   Chloride peroxidase.
AN   Chloroperoxidase.
AN   CPO.
AN   Vanadium haloperoxidase.
CA   RH + Cl(-) + H(2)O(2) = RCl + 2 H(2)O.
CF   Heme.
CC   -!- Brings about the chlorination of a range of organic molecules,
CC       forming stable C-Cl bonds.
CC   -!- Also oxidizes bromide and iodide.
CC   -!- Enzymes of this type are either heme-thiolate proteins, or contain
CC       vanadate.
CC   -!- A secreted enzyme produced by the ascomycetous fungus Caldariomyces
CC       fumago (Leptoxyphium fumago) is an example of the heme-thiolate type.
CC   -!- It catalyzes the production of hypochlorous acid by transferring one
CC       oxygen atom from H(2)O(2) to chloride.
CC   -!- At a separate site it catalyzes the chlorination of activated
CC       aliphatic and aromatic substrates, via HClO and derived chlorine
CC       species.
CC   -!- In the absence of halides, it shows peroxidase (e.g. phenol
CC       oxidation) and peroxygenase activities.
CC   -!- The latter inserts oxygen from H(2)O(2) into, for example, styrene
CC       (side chain epoxidation) and toluene (benzylic hydroxylation),
CC       however, these activities are less pronounced than its activity with
CC       halides.
CC   -!- Has little activity with non-activated substrates such as aromatic
CC       rings, ethers or saturated alkanes.
CC   -!- The chlorinating peroxidase produced by ascomycetous fungi (e.g.
CC       Curvularia inaequalis) is an example of a vanadium chloroperoxidase,
CC       and is related to bromide peroxidase (EC 1.11.1.18).
CC   -!- It contains vanadate and oxidizes chloride, bromide and iodide into
CC       hypohalous acids.
CC   -!- In the absence of halides, it peroxygenates organic sulfides and
CC       oxidizes ABTS (2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid))
CC       but no phenols.
PR   PROSITE; PDOC51405;
DR   P04963, PRXC_CALFU ;  P49053, PRXC_CURIN ;  O31158, PRXC_PSEFL ;
DR   P25026, PRXC_PSEPY ;  O31168, PRXC_STRAU ;  P49323, PRXC_STRLI ;
DR   Q55921, PRXC_SYNY3 ;
//
ID   1.11.1.11
DE   L-ascorbate peroxidase.
AN   Ascorbic acid peroxidase.
CA   2 L-ascorbate + H(2)O(2) + 2 H(+) = L-ascorbate + L-dehydroascorbate +
CA   2 H(2)O.
CF   Heme.
CC   -!- Oxidizes ascorbate and low molecular weight aromatic substrates.
CC   -!- The monodehydroascorbate radical produced is either directly reduced
CC       back to ascorbate by EC 1.6.5.4 or undergoes non-enzymatic
CC       disproportionation to ascorbate and dehydroascorbate.
PR   PROSITE; PDOC00394;
DR   Q05431, APX1_ARATH ;  Q539E5, APX1_HYDVD ;  A2XFC7, APX1_ORYSI ;
DR   Q10N21, APX1_ORYSJ ;  P48534, APX1_PEA   ;  Q1PER6, APX2_ARATH ;
DR   Q9FE01, APX2_ORYSJ ;  Q42564, APX3_ARATH ;  Q01MI9, APX3_ORYSI ;
DR   Q0JEQ2, APX3_ORYSJ ;  Q6ZJJ1, APX4_ORYSJ ;  Q7XZP5, APX5_ARATH ;
DR   P0C0L0, APX5_ORYSJ ;  Q8GY91, APX6_ARATH ;  P0C0L1, APX6_ORYSJ ;
DR   Q7XJ02, APX7_ORYSJ ;  Q69SV0, APX8_ORYSJ ;  Q42592, APXS_ARATH ;
DR   Q42593, APXT_ARATH ;  P85940, APX_PSEMZ  ;
//
ID   1.11.1.12
DE   Phospholipid-hydroperoxide glutathione peroxidase.
AN   Peroxidation-inhibiting protein.
CA   2 glutathione + a lipid hydroperoxide = glutathione disulfide + lipid +
CA   2 H(2)O.
CF   Selenium.
CC   -!- The products of action of EC 1.13.11.12 on phospholipids can act as
CC       acceptor.
CC   -!- Also acts on H(2)O(2), but much more slowly (cf. EC 1.11.1.9).
PR   PROSITE; PDOC00396;
DR   P52032, GPX1_ARATH ;  O24296, GPX1_PEA   ;  O70325, GPX41_MOUSE;
DR   P36970, GPX41_RAT  ;  Q91XR9, GPX42_MOUSE;  Q91XR8, GPX42_RAT  ;
DR   Q9N2J2, GPX4_BOVIN ;  Q32QL6, GPX4_CALJA ;  Q4AEG9, GPX4_CEBAP ;
DR   Q06652, GPX4_CITSI ;  O49069, GPX4_GOSHI ;  O23968, GPX4_HELAN ;
DR   P36969, GPX4_HUMAN ;  Q4AEH1, GPX4_HYLLA ;  Q4AEH0, GPX4_MACFU ;
DR   Q9LEF0, GPX4_MESCR ;  P30708, GPX4_NICSY ;  P36968, GPX4_PIG   ;
DR   Q4AEH2, GPX4_PONPY ;  O24031, GPX4_SOLLC ;  O23814, GPX4_SPIOL ;
DR   Q9FXS3, GPX4_TOBAC ;  O48646, GPX6_ARATH ;  Q8SSH7, GPX_ENCCU  ;
//
ID   1.11.1.13
DE   Manganese peroxidase.
AN   Mn-dependent peroxidase.
CA   2 Mn(2+) + 2 H(+) + H(2)O(2) = 2 Mn(3+) + 2 H(2)O.
CF   Heme.
CC   -!- Involved in the oxidative degradation of lignin in white rot
CC       Basidiomycetes.
PR   PROSITE; PDOC00394;
DR   Q02567, PEM1_PHACH ;  Q70LM3, PEM2_PHLRA ;  P78733, PEM3_PHACH ;
DR   Q96TS6, PEM3_PHLRA ;  P19136, PEM4_PHACH ;  Q9URB1, PEM5_PHACH ;
DR   P83918, PEM_IRPLA  ;
//
ID   1.11.1.14
DE   Lignin peroxidase.
AN   Diarylpropane oxygenase.
AN   Diarylpropane peroxidase.
AN   Ligninase I.
AN   LiP.
CA   (3,4-dimethoxyphenyl)methanol + H(2)O(2) = 3,4-dimethoxybenzaldehyde +
CA   2 H(2)O.
CF   Heme.
CC   -!- Involved in the oxidative breakdown of lignin by white-rot
CC       basidiomycete fungi.
CC   -!- The enzyme from Phanerochaete chrysosporium oxidizes typical
CC       peroxidase dye substrates at the heme iron, a reaction involving the
CC       formation of Compound II (Fe(IV)=O); it also oxidizes (3,4-
CC       dimethoxyphenyl)methanol (veratryl alcohol) to the radical cation.
CC   -!- The bound veratryl alcohol radical is proposed to bring about the
CC       oxidative cleavage of C-C and ether (C-O-C) bonds in lignin model
CC       compounds of the diarylpropane and arylpropane-aryl ether type.
PR   PROSITE; PDOC00394;
DR   P49012, LIG2_PHACH ;  P21764, LIG3_PHACH ;  P11542, LIG4_PHACH ;
DR   P11543, LIG5_PHACH ;  P50622, LIG6_PHACH ;  P06181, LIG8_PHACH ;
DR   P31837, LIGA_PHACH ;  P20011, LIGA_TRAVE ;  P31838, LIGB_PHACH ;
DR   P20012, LIGB_TRAVE ;  P20013, LIGC_TRAVE ;  P20010, LIG_PHLRA  ;
//
ID   1.11.1.15
DE   Peroxiredoxin.
AN   AhpC.
AN   Alkyl hydroperoxide reductase C22.
AN   PRDX.
AN   Prx.
AN   Thioredoxin peroxidase.
AN   TrxPx.
AN   Tryparedoxin peroxidase.
AN   TXNPx.
CA   2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH.
CC   -!- Peroxiredoxins (Prxs) are a ubiquitous family of antioxidant
CC       proteins.
CC   -!- They can be divided into three classes: typical 2-Cys, atypical 2-Cys
CC       and 1-Cys peroxiredoxins.
CC   -!- The peroxidase reaction comprises two steps centered around a redox-
CC       active cysteine called the peroxidatic cysteine.
CC   -!- All three peroxiredoxin classes have the first step in common,
CC       in which the peroxidatic cysteine attacks the peroxide substrate and
CC       is oxidized to S-hydroxycysteine (a sulfenic acid).
CC   -!- The second step of the peroxidase reaction, the regeneration of
CC       cysteine from S-hydroxycysteine, distinguishes the three
CC       peroxiredoxin classes.
CC   -!- For typical 2-Cys Prxs, in the second step, the peroxidatic
CC       S-hydroxycysteine from one subunit is attacked by the 'resolving'
CC       cysteine located in the C-terminus of the second subunit, to form an
CC       intersubunit disulfide bond, which is then reduced by one of several
CC       cell-specific thiol-containing reductants (R'-SH) (e.g. thioredoxin,
CC       AhpF, tryparedoxin or AhpD), completing the catalytic cycle.
CC   -!- In the atypical 2-Cys Prxs, both the peroxidatic cysteine and its
CC       resolving cysteine are in the same polypeptide, so their reaction
CC       forms an intrachain disulfide bond.
CC   -!- To recycle the disulfide, known atypical 2-Cys Prxs appear to use
CC       thioredoxin as an electron donor.
CC   -!- The 1-Cys Prxs conserve only the peroxidatic cysteine, so that its
CC       oxidized form is directly reduced to cysteine by the reductant
CC       molecule.
DR   O17433, 1CPX_DIRIM ;  P38013, AHP1_YEAST ;  P82954, AHPC_ACICA ;
DR   P80239, AHPC_BACSU ;  P83117, AHPC_DELAC ;  P0AE10, AHPC_ECO57 ;
DR   P0AE09, AHPC_ECOL6 ;  P0AE08, AHPC_ECOLI ;  A0R1V9, AHPC_MYCS2 ;
DR   Q7BHK8, AHPC_MYCTU ;  P72314, AHPC_RHORU ;  P0A252, AHPC_SALTI ;
DR   P0A251, AHPC_SALTY ;  P0AE11, AHPC_SHIFL ;  Q2FJN4, AHPC_STAA3 ;
DR   P0A0B7, AHPC_STAA8 ;  Q2YVK2, AHPC_STAAB ;  Q5HIR5, AHPC_STAAC ;
DR   P0A0B5, AHPC_STAAM ;  P99074, AHPC_STAAN ;  Q6GJR7, AHPC_STAAR ;
DR   Q6GC91, AHPC_STAAS ;  P0A0B6, AHPC_STAAW ;  Q5HRY1, AHPC_STAEQ ;
DR   Q8CMQ2, AHPC_STAES ;  Q4L376, AHPC_STAHJ ;  Q49UT8, AHPC_STAS1 ;
DR   Q1IJ49, AHPD_ACIBL ;  C1F4K1, AHPD_ACIC5 ;  B8J9Z2, AHPD_ANAD2 ;
DR   Q2IMQ8, AHPD_ANADE ;  A7HCA3, AHPD_ANADF ;  B4UA87, AHPD_ANASK ;
DR   A8HQP5, AHPD_AZOC5 ;  B2IHZ4, AHPD_BEII9 ;  Q9ANL0, AHPD_BRAJA ;
DR   A5ENR3, AHPD_BRASB ;  A4YYT0, AHPD_BRASO ;  B2SAW2, AHPD_BRUA1 ;
DR   Q2YKW2, AHPD_BRUA2 ;  Q578J2, AHPD_BRUAB ;  A9MBZ4, AHPD_BRUC2 ;
DR   Q8YCF2, AHPD_BRUME ;  A9WZ04, AHPD_BRUSI ;  Q8FVW4, AHPD_BRUSU ;
DR   B8GVX4, AHPD_CAUCN ;  Q9A268, AHPD_CAUCR ;  C3PGV9, AHPD_CORA7 ;
DR   Q6NGT4, AHPD_CORDI ;  C4LJ26, AHPD_CORK4 ;  B6IZ19, AHPD_COXB2 ;
DR   A9KBI4, AHPD_COXBN ;  A9N917, AHPD_COXBR ;  Q83BM5, AHPD_COXBU ;
DR   Q0RH96, AHPD_FRAAA ;  A8L1J2, AHPD_FRASN ;  A9H8D2, AHPD_GLUDA ;
DR   Q0BUC5, AHPD_GRABC ;  Q0BXT2, AHPD_HYPNA ;  Q0AKM4, AHPD_MARMM ;
DR   B0UAJ8, AHPD_METS4 ;  B8EJZ2, AHPD_METSB ;  A0QGI9, AHPD_MYCA1 ;
DR   B1MJX0, AHPD_MYCA9 ;  P0A5N5, AHPD_MYCBO ;  A1KLC4, AHPD_MYCBP ;
DR   C1AQZ5, AHPD_MYCBT ;  B2HD59, AHPD_MYCMM ;  Q73ZL4, AHPD_MYCPA ;
DR   Q50441, AHPD_MYCS2 ;  A5U5C5, AHPD_MYCTA ;  P0A5N4, AHPD_MYCTU ;
DR   A0PSD4, AHPD_MYCUA ;  Q5YT53, AHPD_NOCFA ;  A6X5N3, AHPD_OCHA4 ;
DR   B6IQZ3, AHPD_RHOCS ;  C0ZYQ9, AHPD_RHOE4 ;  Q07I00, AHPD_RHOP5 ;
DR   Q20Y19, AHPD_RHOPB ;  Q02BZ5, AHPD_SOLUE ;  A5VCB6, AHPD_SPHWW ;
DR   Q82IC5, AHPD_STRAW ;  Q7AKI6, AHPD_STRCO ;  B1W2G7, AHPD_STRGG ;
DR   Q9X5V1, AHPD_STRVD ;  Q96291, BAS1A_ARATH;  Q9C5R8, BAS1B_ARATH;
DR   Q96468, BAS1_HORVU ;  Q6ER94, BAS1_ORYSJ ;  P84729, BAS1_PINST ;
DR   O24364, BAS1_SPIOL ;  P80602, BAS1_WHEAT ;  O53911, BCPB_MYCTU ;
DR   Q796Y8, BCP_BACSU  ;  Q9ZHF0, BCP_BUCAP  ;  Q83CY8, BCP_COXBU  ;
DR   P0AE54, BCP_ECO57  ;  P0AE53, BCP_ECOL6  ;  P0AE52, BCP_ECOLI  ;
DR   P44411, BCP_HAEIN  ;  Q9ZMU4, BCP_HELPJ  ;  P55979, BCP_HELPY  ;
DR   O53226, BCP_MYCTU  ;  P0AE55, BCP_SHIFL  ;  P19476, CR29_ENTHI ;
DR   P40553, DOT5_YEAST ;  P40581, GPX3_YEAST ;  P56577, MALF2_MALFU;
DR   P56578, MALF3_MALFU;  P0C0L2, OSMC_ECOLI ;  P0C0L3, OSMC_SHIFL ;
DR   Q9MB35, PERQ_SEDLI ;  Q6UBI3, PERQ_SUASA ;  O43099, PMP20_ASPFU;
DR   Q5ASN8, PMP20_EMENI;  Q01116, PMP20_LIPKO;  O14313, PMP20_SCHPO;
DR   P14292, PMPA_CANBO ;  P14293, PMPB_CANBO ;  Q69TY4, PR2E1_ORYSJ;
DR   Q7F8S5, PR2E2_ORYSJ;  Q5E947, PRDX1_BOVIN;  P0CB50, PRDX1_CHICK;
DR   Q9JKY1, PRDX1_CRIGR;  Q9V3P0, PRDX1_DROME;  Q6DV14, PRDX1_GECJA;
DR   Q06830, PRDX1_HUMAN;  P35700, PRDX1_MOUSE;  Q6B4U9, PRDX1_MYOLU;
DR   Q63716, PRDX1_RAT  ;  Q9BGI3, PRDX2_BOVIN;  Q8K3U7, PRDX2_CRIGR;
DR   P32119, PRDX2_HUMAN;  Q2PFZ3, PRDX2_MACFA;  Q61171, PRDX2_MOUSE;
DR   P52552, PRDX2_PIG  ;  Q5RC63, PRDX2_PONAB;  P35704, PRDX2_RAT  ;
DR   P35705, PRDX3_BOVIN;  P30048, PRDX3_HUMAN;  P20108, PRDX3_MOUSE;
DR   Q5REY3, PRDX3_PONAB;  Q9Z0V6, PRDX3_RAT  ;  Q9BGI2, PRDX4_BOVIN;
DR   P0CV91, PRDX4_CROAT;  Q555L5, PRDX4_DICDI;  Q13162, PRDX4_HUMAN;
DR   O08807, PRDX4_MOUSE;  Q9Z0V5, PRDX4_RAT  ;  Q9BGI1, PRDX5_BOVIN;
DR   Q9GLW7, PRDX5_CHLAE;  P30044, PRDX5_HUMAN;  P86241, PRDX5_MESAU;
DR   P99029, PRDX5_MOUSE;  Q9GLW9, PRDX5_PAPHA;  Q9R063, PRDX5_RAT  ;
DR   P83200, PRDX5_VULVU;  O77834, PRDX6_BOVIN;  Q5ZJF4, PRDX6_CHICK;
DR   P30041, PRDX6_HUMAN;  Q2PFL9, PRDX6_MACFA;  P86215, PRDX6_MESAU;
DR   O08709, PRDX6_MOUSE;  Q9TSX9, PRDX6_PIG  ;  Q5R7E0, PRDX6_PONAB;
DR   O35244, PRDX6_RAT  ;  Q9NL98, PRDX_ASCSU ;  P34227, PRX1_YEAST ;
DR   Q7G959, PRX2A_ARATH;  Q9XEX2, PRX2B_ARATH;  Q9SRZ4, PRX2C_ARATH;
DR   Q9FR35, PRX2C_ORYSJ;  O22711, PRX2D_ARATH;  Q949U7, PRX2E_ARATH;
DR   Q9M7T0, PRX2F_ARATH;  Q9SDD6, PRX2F_ORYSJ;  P44758, PRX5_HAEIN ;
DR   Q9LU86, PRXQ_ARATH ;  Q75SY5, PRXQ_GENTR ;  P0C5D4, PRXQ_ORYSI ;
DR   P0C5D5, PRXQ_ORYSJ ;  Q6QPJ6, PRXQ_POPJC ;  Q5S1S6, PRXQ_WHEAT ;
DR   Q9L3Q5, PRXU_EUBAC ;  O94561, PRX_SCHPO  ;  P23161, R20K_CLOPA ;
DR   P0C5C8, REHYA_ORYSI;  P0C5C9, REHYA_ORYSJ;  P0C5D0, REHYB_ORYSI;
DR   P0C5D1, REHYB_ORYSJ;  O04005, REHY_ARATH ;  P52571, REHY_BROSE ;
DR   P52572, REHY_HORVU ;  A2SZW8, REHY_MAIZE ;  Q6E2Z6, REHY_MEDTR ;
DR   P52574, REHY_TORRU ;  Q6W8Q2, REHY_WHEAT ;  P48822, TDX1_BRUMA ;
DR   Q21824, TDX1_CAEEL ;  Q17172, TDX2_BRUMA ;  Q6L240, TDXH1_PICTO;
DR   Q55060, TDXH1_SULME;  Q974S8, TDXH1_SULTO;  Q9HKX0, TDXH1_THEAC;
DR   Q8RCY5, TDXH1_THETN;  Q6L140, TDXH2_PICTO;  O33665, TDXH2_SULME;
DR   Q96XS5, TDXH2_SULTO;  Q9HJL3, TDXH2_THEAC;  Q8R844, TDXH2_THETN;
DR   Q9Y9L0, TDXH_AERPE ;  O67024, TDXH_AQUAE ;  O29969, TDXH_ARCFU ;
DR   Q8KBN8, TDXH_CHLTE ;  A2BJD9, TDXH_HYPBU ;  A8A9P0, TDXH_IGNH4 ;
DR   Q58146, TDXH_METJA ;  A4FWZ9, TDXH_METM5 ;  Q8PYP6, TDXH_METMA ;
DR   Q6LY19, TDXH_METMP ;  O26262, TDXH_METTH ;  Q57109, TDXH_METTM ;
DR   A6UPH7, TDXH_METVS ;  Q74NC6, TDXH_NANEQ ;  Q9UZV4, TDXH_PYRAB ;
DR   Q8U218, TDXH_PYRFU ;  O58966, TDXH_PYRHO ;  Q5JF30, TDXH_PYRKO ;
DR   A3DKL1, TDXH_STAMF ;  P95895, TDXH_SULSO ;  Q9WZR4, TDXH_THEMA ;
DR   A5IIX7, TDXH_THEP1 ;  Q979N7, TDXH_THEVO ;  Q73RS4, TDXH_TREDE ;
DR   Q90384, TDX_CYNPY  ;  Q8T6C4, TDX_ECHGR  ;  Q8SS85, TDX_ENCCU  ;
DR   P91883, TDX_FASHE  ;  Q91191, TDX_ONCMY  ;  Q26695, TDX_TRYBR  ;
DR   Q9Y7F0, TSA1_CANAL ;  O74887, TSA1_SCHPO ;  P34760, TSA1_YEAST ;
DR   Q04120, TSA2_YEAST ;  P57279, TSAA_BUCAI ;  Q8K9W0, TSAA_BUCAP ;
DR   Q89AS1, TSAA_BUCBP ;  P56876, TSAA_HELPJ ;  P21762, TSAA_HELPY ;
DR   P52570, TSA_ONCVO  ;  P73728, Y1621_SYNY3;  P65688, Y2238_MYCTU;
DR   P65689, Y2262_MYCBO;  Q53212, Y4VD_RHISN ;  Q55624, Y755_SYNY3 ;
DR   P49537, YCF42_ODOSI;  P51272, YCF42_PORPU;  Q1XDL4, YCF42_PORYE;
DR   P26830, YNDH_BACYN ;  O69777, YRP2_RHIET ;
//
ID   1.11.1.16
DE   Versatile peroxidase.
AN   Hybrid peroxidase.
AN   Polyvalent peroxidase.
AN   VP.
CA   (1) Reactive Black 5 + H(2)O(2) = oxidized Reactive Black 5 + 2 H(2)O.
CA   (2) Donor + H(2)O(2) = oxidized donor + 2 H(2)O.
CF   Heme.
CC   -!- This ligninolytic peroxidase combines the substrate-specificity
CC       characteristics of the two other ligninolytic peroxidases,
CC       EC 1.11.1.13 and EC 1.11.1.14.
CC   -!- Also able to oxidize phenols, hydroquinones and both low- and high-
CC       redox-potential dyes, due to a hybrid molecular architecture that
CC       involves multiple binding sites for substrates.
PR   PROSITE; PDOC00394;
DR   Q9UR19, VPL1_PLEER ;  O94753, VPL2_PLEER ;  Q9UVP6, VPS1_PLEER ;
//
ID   1.11.1.17
DE   Glutathione amide-dependent peroxidase.
CA   2 glutathione amide + H(2)O(2) = glutathione amide disulfide + 2 H(2)O.
CC   -!- This enzyme, which has been characterized from the proteobacterium
CC       Marichromatium gracile, is a chimeric protein, containing a
CC       peroxiredoxin-like N-terminus and a glutaredoxin-like C terminus.
CC   -!- The enzyme has peroxidase activity toward hydrogen peroxide and
CC       several small alkyl hydroperoxides, and is thought to represent an
CC       early adaptation for fighting oxidative stress.
CC   -!- The glutathione amide disulfide produced by this enzyme can be
CC       restored to glutathione amide by EC 1.8.1.16.
//
ID   1.11.1.18
DE   Bromide peroxidase.
AN   Bromoperoxidase.
AN   Eosinophil peroxidase.
CA   RH + HBr + H(2)O(2) = RBr + 2 H(2)O.
CC   -!- Bromoperoxidases of red and brown marine algae (Rhodophyta and
CC       Phaeophyta) contain vanadate.
CC   -!- They catalyze the bromination of a range of organic molecules such as
CC       sesquiterpenes, forming stable C-Br bonds.
CC   -!- Bromoperoxidases also oxidize iodides.
DR   P81701, PRXV_ASCNO ;  Q8LLW7, PRXV_COROI ;  O81959, PRXV_CORPI ;
//
ID   1.11.1.19
DE   Dye decolorizing peroxidase.
AN   DyP.
AN   DyP-type peroxidase.
CA   Reactive Blue 5 + H(2)O(2) + 2 H(+) = oxidized Reactive Blue 5 + 2 H(2)O.
CC   -!- Heme proteins with proximal histidine secreted by basidiomycetous
CC       fungi and eubacteria.
CC   -!- They are similar to EC 1.11.1.16 versatile peroxidase (oxidation of
CC       Reactive Black 5, phenols, veratryl alcohol), but differ from the
CC       latter in their ability to efficiently oxidize a number of
CC       recalcitrant anthraquinone dyes, and inability to oxidize Mn(II).
CC   -!- The model substrate Reactive Blue 5 is converted with high efficiency
CC       via a so far unique mechanism that combines oxidative and hydrolytic
CC       steps and leads to the formation of phthalic acid.
CC   -!- Bacterial TfuDyP catalyzes sulfoxidation.
//
ID   1.11.1.20
DE   Prostamide/prostaglandin F(2-alpha) synthase.
AN   Prostamide F synthase.
AN   Prostamide/PGF synthase.
AN   Prostamide/prostaglandin F synthase.
AN   TPGF synthase.
CA   Thioredoxin + prostaglandin H(2) = thioredoxin disulfide + prostaglandin
CA   F(2-alpha).
CC   -!- The enzyme contains a thioredoxin-type disulfide as a catalytic
CC       group.
CC   -!- Prostamide H(2) and prostaglandin H(2) are the best substrates; the
CC       latter is converted to prostaglandin F(2-alpha).
CC   -!- The enzyme also reduces tert-butyl hydroperoxide, cumene
CC       hydroperoxide and H(2)O(2), but not prostaglandin D(2) or
CC       prostaglandin E(2).
DR   Q58CY6, PGFS_BOVIN ;  Q6NV24, PGFS_DANRE ;  Q8TBF2, PGFS_HUMAN ;
DR   Q9DB60, PGFS_MOUSE ;  A9CQL8, PGFS_PIG   ;  Q5R7S9, PGFS_PONAB ;
DR   C1C416, PGFS_RANCA ;  D3ZVR7, PGFS_RAT   ;  B5X9L9, PGFS_SALSA ;
DR   Q6AZG8, PGFS_XENLA ;  Q28IJ3, PGFS_XENTR ;
//
ID   1.11.1.21
DE   Catalase peroxidase.
CA   (1) Donor + H(2)O(2) = oxidized donor + 2 H(2)O.
CA   (2) 2 H(2)O(2) = O(2) + 2 H(2)O.
CC   -!- Differs from EC 1.11.1.7, peroxidase, in having a relatively high
CC       catalase (EC 1.11.1.6) activity with H(2)O(2) as donor, releasing
CC       O(2); both activities use the same heme active site.
CC   -!- In Mycobacterium tuberculosis it is responsible for activation of the
CC       commonly used antitubercular drug, isoniazid.
DR   A6TNI2, KATG1_ALKMQ;  B1YTH4, KATG1_BURA4;  Q1BYZ9, KATG1_BURCA;
DR   B1JVZ2, KATG1_BURCC;  A0K4Q2, KATG1_BURCH;  B4EE21, KATG1_BURCJ;
DR   Q0BI48, KATG1_BURCM;  A4JBP6, KATG1_BURVG;  B3PC77, KATG1_CELJU;
DR   Q471D2, KATG1_CUPPJ;  Q7A978, KATG1_ECO57;  Q5V0S5, KATG1_HALMA;
DR   Q5QXC3, KATG1_IDILO;  Q5X2D9, KATG1_LEGPA;  A5IF70, KATG1_LEGPC;
DR   Q5ZSX7, KATG1_LEGPH;  Q5WU58, KATG1_LEGPL;  Q9ZGM4, KATG1_LEGPN;
DR   A4R5S9, KATG1_MAGO7;  O08404, KATG1_MYCFO;  A0R609, KATG1_MYCS2;
DR   A1TA09, KATG1_MYCVP;  A1SAR6, KATG1_SHEAM;  Q082Q2, KATG1_SHEFN;
DR   Q8E981, KATG1_SHEON;  A0KRY0, KATG1_SHESA;  Q0HNH6, KATG1_SHESM;
DR   Q0HQB2, KATG1_SHESR;  Q87J02, KATG1_VIBPA;  A6TV07, KATG2_ALKMQ;
DR   B1Z5M2, KATG2_BURA4;  Q1BQP0, KATG2_BURCA;  B1K6I9, KATG2_BURCC;
DR   A0B2Q6, KATG2_BURCH;  Q4F6N6, KATG2_BURCJ;  Q0B385, KATG2_BURCM;
DR   A4JPG0, KATG2_BURVG;  B3PEP6, KATG2_CELJU;  Q470S7, KATG2_CUPPJ;
DR   Q7BSW8, KATG2_ECO57;  O59651, KATG2_HALMA;  Q5QWH3, KATG2_IDILO;
DR   Q5X8J8, KATG2_LEGPA;  A5IA67, KATG2_LEGPC;  Q5ZZ17, KATG2_LEGPH;
DR   Q5WZY1, KATG2_LEGPL;  Q9WXB9, KATG2_LEGPN;  A4QUT2, KATG2_MAGO7;
DR   O08405, KATG2_MYCFO;  A0QXX7, KATG2_MYCS2;  A1T9D9, KATG2_MYCVP;
DR   A1S3J7, KATG2_SHEAM;  Q07YF5, KATG2_SHEFN;  Q8EIV5, KATG2_SHEON;
DR   A0L153, KATG2_SHESA;  Q0HES2, KATG2_SHESM;  Q0HZ78, KATG2_SHESR;
DR   Q87I38, KATG2_VIBPA;  A0QYP1, KATG3_MYCS2;  B0C4G1, KATG_ACAM1 ;
DR   A1TRV8, KATG_ACIAC ;  B7H0U3, KATG_ACIB3 ;  B7I4D5, KATG_ACIB5 ;
DR   B2I352, KATG_ACIBC ;  Q1IRZ2, KATG_ACIBL ;  A3M1S3, KATG_ACIBT ;
DR   B0V4K1, KATG_ACIBY ;  C1F960, KATG_ACIC5 ;  A5FZM1, KATG_ACICJ ;
DR   A4SS04, KATG_AERS4 ;  B9JKI5, KATG_AGRRK ;  Q7CVH1, KATG_AGRT5 ;
DR   B9K0G2, KATG_AGRVS ;  Q0A8G6, KATG_ALHEH ;  B4RW28, KATG_ALTMD ;
DR   A8EV24, KATG_ARCB4 ;  O28050, KATG_ARCFU ;  A1C8R3, KATG_ASPCL ;
DR   B0YAK0, KATG_ASPFC ;  Q7Z7W6, KATG_ASPFU ;  A2Q7T1, KATG_ASPNC ;
DR   Q2TW34, KATG_ASPOR ;  Q0CD12, KATG_ASPTN ;  A8IHK8, KATG_AZOC5 ;
DR   A1K9V0, KATG_AZOSB ;  Q9KEE6, KATG_BACHD ;  B2II34, KATG_BEII9 ;
DR   Q8X1N3, KATG_BLUGR ;  Q2KTI4, KATG_BORA1 ;  Q89WB4, KATG_BRAJA ;
DR   A5EQ55, KATG_BRASB ;  A4YNR8, KATG_BRASO ;  Q9AP06, KATG_BURCE ;
DR   A9AGE5, KATG_BURM1 ;  A3MPB8, KATG_BURM7 ;  A2S5D5, KATG_BURM9 ;
DR   Q62H74, KATG_BURMA ;  A1V0A6, KATG_BURMS ;  A3NZ22, KATG_BURP0 ;
DR   Q3JNW6, KATG_BURP1 ;  A3NDB2, KATG_BURP6 ;  B2T4H0, KATG_BURPP ;
DR   Q939D2, KATG_BURPS ;  Q39JF1, KATG_BURS3 ;  Q2SZ20, KATG_BURTA ;
DR   Q13US7, KATG_BURXL ;  O31066, KATG_CAUCR ;  B0SX45, KATG_CAUSK ;
DR   Q2H7U1, KATG_CHAGB ;  Q3ATL6, KATG_CHLCH ;  B3EEA0, KATG_CHLL2 ;
DR   B3EKE9, KATG_CHLPB ;  A1BEI1, KATG_CHLPD ;  Q1R185, KATG_CHRSD ;
DR   A8AKX8, KATG_CITK8 ;  B2V515, KATG_CLOBA ;  B2TJE9, KATG_CLOBB ;
DR   Q486C8, KATG_COLP3 ;  Q0K815, KATG_CUPNH ;  Q479B7, KATG_DECAR ;
DR   B8FDS1, KATG_DESAA ;  C6C1T6, KATG_DESAD ;  Q24YU1, KATG_DESHY ;
DR   A9A0F0, KATG_DESOH ;  A8LTG4, KATG_DINSH ;  A7ZUG1, KATG_ECO24 ;
DR   B1XBA8, KATG_ECODH ;  A8A750, KATG_ECOHS ;  A1AIC1, KATG_ECOK1 ;
DR   Q0TAB7, KATG_ECOL5 ;  Q8FBA9, KATG_ECOL6 ;  B1IVD5, KATG_ECOLC ;
DR   P13029, KATG_ECOLI ;  P0C8F0, KATG_ECOLX ;  B1LNQ3, KATG_ECOSM ;
DR   Q1R3X0, KATG_ECOUT ;  Q4G4B1, KATG_EDWTA ;  Q96VT4, KATG_EMENI ;
DR   A4WG57, KATG_ENT38 ;  A7MJS4, KATG_ENTS8 ;  Q6D5X9, KATG_ERWCT ;
DR   B2VFG0, KATG_ERWT9 ;  Q2N806, KATG_ERYLH ;  A5FD11, KATG_FLAJ1 ;
DR   A6H0C4, KATG_FLAPJ ;  B0TYQ6, KATG_FRAP2 ;  Q2JBP8, KATG_FRASC ;
DR   A8LBC6, KATG_FRASN ;  Q14IA9, KATG_FRAT1 ;  A7NDL0, KATG_FRATF ;
DR   Q2A298, KATG_FRATH ;  B2SDI5, KATG_FRATM ;  A0Q5L1, KATG_FRATN ;
DR   Q0BKW5, KATG_FRATO ;  Q5NGV7, KATG_FRATT ;  A4IZ86, KATG_FRATW ;
DR   Q5KZ91, KATG_GEOKA ;  B3EBB7, KATG_GEOLS ;  P14412, KATG_GEOSE ;
DR   Q74BE1, KATG_GEOSL ;  C6DYB7, KATG_GEOSM ;  A4INM5, KATG_GEOTN ;
DR   Q7NGW6, KATG_GLOVI ;  Q0BRH7, KATG_GRABC ;  A0LZM9, KATG_GRAFK ;
DR   Q2SHA6, KATG_HAHCH ;  A1WUH1, KATG_HALHL ;  B0R9V8, KATG_HALS3 ;
DR   O73955, KATG_HALSA ;  A2RPW9, KATG_HERSE ;  D8INT8, KATG_HERSS ;
DR   Q0C0D1, KATG_HYPNA ;  A6SY97, KATG_JANMA ;  Q28S09, KATG_JANSC ;
DR   A6T9H9, KATG_KLEP7 ;  B0SD19, KATG_LEPBA ;  B0SLJ6, KATG_LEPBP ;
DR   B1Y7V8, KATG_LEPCP ;  A1TZH9, KATG_MARAV ;  Q0AL71, KATG_MARMM ;
DR   A6VVN4, KATG_MARMS ;  Q11KP9, KATG_MESSB ;  Q8TS34, KATG_METAC ;
DR   A7I6W6, KATG_METB6 ;  Q2FSF4, KATG_METHJ ;  B3E099, KATG_METI4 ;
DR   A2SMA4, KATG_METPP ;  B1M869, KATG_METRJ ;  A0QGA4, KATG_MYCA1 ;
DR   B1MBD0, KATG_MYCA9 ;  P46817, KATG_MYCBO ;  A1KJX3, KATG_MYCBP ;
DR   C1API8, KATG_MYCBT ;  A4TA35, KATG_MYCGI ;  Q04657, KATG_MYCIT ;
DR   B2HE73, KATG_MYCMM ;  Q73ZD5, KATG_MYCPA ;  A3Q016, KATG_MYCSJ ;
DR   A1UGG4, KATG_MYCSK ;  P0C580, KATG_MYCSM ;  Q1B8J4, KATG_MYCSS ;
DR   A5U3S7, KATG_MYCTA ;  Q08129, KATG_MYCTU ;  A0PQH6, KATG_MYCUA ;
DR   Q9R2E9, KATG_MYCVN ;  Q3IQZ9, KATG_NATPD ;  A1DAL6, KATG_NEOFI ;
DR   Q8X182, KATG_NEUCR ;  Q1QS58, KATG_NITHX ;  Q3SWP3, KATG_NITWN ;
DR   Q5YVJ4, KATG_NOCFA ;  A1SF13, KATG_NOCSJ ;  Q2G479, KATG_NOVAD ;
DR   A1B4Z0, KATG_PARDP ;  A7HT94, KATG_PARL1 ;  C6DK50, KATG_PECCP ;
DR   Q3A5D3, KATG_PELCD ;  B4SAT7, KATG_PELPB ;  A1ANT3, KATG_PELPD ;
DR   Q8NJN2, KATG_PENMA ;  C0QQ02, KATG_PERMH ;  Q0U324, KATG_PHANO ;
DR   B4R8U3, KATG_PHEZH ;  B2ASU5, KATG_PODAN ;  Q12FQ6, KATG_POLSJ ;
DR   A4T0J1, KATG_POLSQ ;  B4S3B3, KATG_PROA2 ;  Q48E42, KATG_PSE14 ;
DR   Q15UE5, KATG_PSEA6 ;  Q1IAY6, KATG_PSEE4 ;  Q4KD86, KATG_PSEF5 ;
DR   A4XZ62, KATG_PSEMY ;  A5W241, KATG_PSEP1 ;  Q3KE62, KATG_PSEPF ;
DR   B0KNK9, KATG_PSEPG ;  Q88GQ0, KATG_PSEPK ;  B1J7Q1, KATG_PSEPW ;
DR   Q87WL6, KATG_PSESM ;  Q4ZNN4, KATG_PSEU2 ;  A4VK13, KATG_PSEU5 ;
DR   A1SWM1, KATG_PSYIN ;  B2WH84, KATG_PYRTR ;  Q1LC96, KATG_RALME ;
DR   B2UBU5, KATG_RALPJ ;  Q8Y1B4, KATG_RALSO ;  B3Q4F9, KATG_RHIE6 ;
DR   Q2JZT8, KATG_RHIEC ;  Q1M498, KATG_RHIL3 ;  Q987S0, KATG_RHILO ;
DR   Q8RJZ6, KATG_RHILP ;  Q92XG8, KATG_RHIME ;  Q9R708, KATG_RHIRD ;
DR   Q6W102, KATG_RHISN ;  Q7UUW9, KATG_RHOBA ;  P37743, KATG_RHOCA ;
DR   C0ZSW0, KATG_RHOE4 ;  C1AV76, KATG_RHOOB ;  Q2J2I9, KATG_RHOP2 ;
DR   Q07V22, KATG_RHOP5 ;  Q6NCP1, KATG_RHOPA ;  Q21CF0, KATG_RHOPB ;
DR   Q13EM6, KATG_RHOPS ;  B3QAA7, KATG_RHOPT ;  A4WXS6, KATG_RHOS5 ;
DR   Q0S5Y0, KATG_RHOSR ;  Q167Q3, KATG_ROSDO ;  Q21DT6, KATG_SACD2 ;
DR   A4FIR1, KATG_SACEN ;  A8M0L5, KATG_SALAI ;  A9MI19, KATG_SALAR ;
DR   Q57HA8, KATG_SALCH ;  B4TCP6, KATG_SALHS ;  B4T0V5, KATG_SALNS ;
DR   Q5PK60, KATG_SALPA ;  A9N0F0, KATG_SALPB ;  B5BJM5, KATG_SALPK ;
DR   Q2RZX7, KATG_SALRD ;  B4TQG7, KATG_SALSV ;  Q8Z303, KATG_SALTI ;
DR   A4X6K7, KATG_SALTO ;  P17750, KATG_SALTY ;  A8GGQ0, KATG_SERP5 ;
DR   A3D0Y7, KATG_SHEB5 ;  A6WS27, KATG_SHEB8 ;  A9L1H8, KATG_SHEB9 ;
DR   Q12PF6, KATG_SHEDO ;  B0TRN5, KATG_SHEHH ;  A3QAT3, KATG_SHELP ;
DR   A4Y2G4, KATG_SHEPC ;  A1REM5, KATG_SHESW ;  B1KFI8, KATG_SHEWM ;
DR   B2TWE0, KATG_SHIB3 ;  Q31U45, KATG_SHIBS ;  Q0SY48, KATG_SHIF8 ;
DR   Q83IT3, KATG_SHIFL ;  Q3YV31, KATG_SHISS ;  Q5LLG6, KATG_SILPO ;
DR   Q1GCU3, KATG_SILST ;  A6UKC3, KATG_SINMW ;  Q02A20, KATG_SOLUE ;
DR   Q1GR67, KATG_SPHAL ;  A0ACX8, KATG_STRAM ;  Q9RJH9, KATG_STRCO ;
DR   B1W5Q9, KATG_STRGG ;  O87864, KATG_STRRE ;  Q67LP5, KATG_SYMTH ;
DR   Q31MN3, KATG_SYNE7 ;  B1XK45, KATG_SYNP2 ;  Q5MZ99, KATG_SYNP6 ;
DR   A5GJV3, KATG_SYNPW ;  A5GTX8, KATG_SYNR3 ;  Q3AN75, KATG_SYNSC ;
DR   P73911, KATG_SYNY3 ;  A8F6I7, KATG_THELT ;  B8GPM6, KATG_THISH ;
DR   Q4P914, KATG_USTMA ;  A5F7X7, KATG_VIBC3 ;  Q9KRS6, KATG_VIBCH ;
DR   C3LMN9, KATG_VIBCM ;  A7MZ01, KATG_VIBHB ;  Q8D951, KATG_VIBVU ;
DR   Q7MLC1, KATG_VIBVY ;  Q8PMX4, KATG_XANAC ;  Q3BVY2, KATG_XANC5 ;
DR   Q4US88, KATG_XANC8 ;  B0RXD3, KATG_XANCB ;  Q8PBB7, KATG_XANCP ;
DR   B2I5Z2, KATG_XYLF2 ;  Q9PBB2, KATG_XYLFA ;  B0U3C6, KATG_XYLFM ;
DR   Q87C18, KATG_XYLFT ;  A7FLT3, KATG_YERP3 ;  Q1C435, KATG_YERPA ;
DR   B2K5B9, KATG_YERPB ;  Q9X6B0, KATG_YERPE ;  A9R0X4, KATG_YERPG ;
DR   Q1CLM4, KATG_YERPN ;  A4TQ37, KATG_YERPP ;  Q66E82, KATG_YERPS ;
DR   B1JJB5, KATG_YERPY ;
//
ID   1.11.2.1
DE   Unspecific peroxygenase.
AN   Haloperoxidase-peroxygenase.
CA   RH + H(2)O(2) = ROH + H(2)O.
CF   Heme-thiolate.
CC   -!- Enzymes of this type include glycoproteins secreted by agaric
CC       basidiomycetes.
CC   -!- They catalyze the insertion of an oxygen atom from H(2)O(2) into a
CC       wide variety of substrates, including aromatic rings such as
CC       naphthalene, toluene, phenanthrene, pyrene and p-nitrophenol,
CC       recalcitrant heterocycles such as pyridine, dibenzofuran, various
CC       ethers (resulting in O-dealkylation) and alkanes such as propane,
CC       hexane and cyclohexane.
CC   -!- Reactions catalyzed include hydroxylation, epoxidation, N-oxidation,
CC       sulfooxidation, O- and N-dealkylation, bromination and one-electron
CC       oxidations.
CC   -!- They have little or no activity toward chloride.
CC   -!- Mechanistically, the catalytic cycle of unspecific (mono)-
CC       peroxygenases combines elements of the 'shunt' pathway of cytochrome
CC       P450s (a side activity that utilizes a peroxide in place of dioxygen
CC       and NAD(P)H) and the classic heme peroxidase cycle.
PR   PROSITE; PDOC00394;
//
ID   1.11.2.2
DE   Myeloperoxidase.
AN   MPO.
AN   Verdoperoxidase.
CA   Cl(-) + H(2)O(2) + H(+) = HClO + H(2)O.
CF   Calcium; Heme.
CC   -!- Is present in phagosomes of neutrophils and monocytes, where the
CC       hypochlorite produced is strongly bactericidal.
CC   -!- It differs from EC 1.11.1.10 in its preference for formation of
CC       hypochlorite over the chlorination of organic substrates under
CC       physiological conditions (pH 5-8).
CC   -!- Hypochlorite in turn forms a number of antimicrobial products (Cl(2),
CC       chloramines, hydroxyl radical, singlet oxygen).
CC   -!- MPO also oxidizes bromide, iodide and thiocyanate.
CC   -!- In the absence of halides, it oxidizes phenols and has a moderate
CC       peroxygenase activity toward styrene.
PR   PROSITE; PDOC00394;
DR   P05164, PERM_HUMAN ;  P11247, PERM_MOUSE ;
//
ID   1.11.2.3
DE   Plant seed peroxygenase.
AN   Plant peroxygenase.
AN   Soybean peroxygenase.
CA   RH + ROOH = ROH + ROH.
CF   Heme.
CC   -!- A heme protein with calcium binding motif (caleosin-type).
CC   -!- Enzymes of this type include membrane-bound proteins found in seeds
CC       of different plants.
CC   -!- They catalyze the direct transfer of one oxygen atom from an organic
CC       hydroperoxide, which is reduced into its corresponding alcohol to a
CC       substrate which will be oxidized.
CC   -!- Reactions catalyzed include hydroxylation, epoxidation and
CC       sulfoxidation.
CC   -!- Preferred substrate and cosubstrate are unsaturated fatty acids and
CC       fatty acid hydroperoxides, respectively.
CC   -!- Plant seed peroxygenase is involved in the synthesis of cutin.
//
ID   1.11.2.4
DE   Fatty-acid peroxygenase.
AN   CYP152A1.
AN   Fatty acid hydroxylase.
AN   P450 peroxygenase.
AN   P450SP-alpha.
CA   Fatty acid + H(2)O(2) = 3- or 2-hydroxy fatty acid + H(2)O.
CF   Heme-thiolate.
CC   -!- A cytosolic heme-thiolate protein with sequence homology to P450
CC       monooxygenases.
CC   -!- Unlike the latter, it needs neither NAD(P)H, dioxygen nor specific
CC       reductases for function.
CC   -!- Enzymes of this type are produced by bacteria (e.g. Sphingomonas
CC       paucimobilis, Bacillus subtilis).
CC   -!- Catalytic turnover rates are high compared with those of
CC       monooxygenation reactions as well as peroxide shunt reactions
CC       catalyzed by the common P450s.
CC   -!- A model substrate is myristate, but other saturated and unsaturated
CC       fatty acids are also hydroxylated.
CC   -!- Oxidizes the peroxidase substrate 3,3,5,5-tetramethylbenzidine (TMB)
CC       and peroxygenates aromatic substrates in a fatty-acid-dependent
CC       reaction.
PR   PROSITE; PDOC00081;
DR   O31440, CYPC_BACSU ;
//
ID   1.12.1.1
DE   Transferred entry: 1.12.7.2.
//
ID   1.12.1.2
DE   Hydrogen dehydrogenase.
AN   Bidirectional hydrogenase.
AN   H(2):NAD(+) oxidoreductase.
AN   Hydrogenase.
AN   NAD-linked hydrogenase.
CA   H(2) + NAD(+) = H(+) + NADH.
CF   FAD or FMN; Iron-sulfur; Nickel.
DR   P22317, HOXF_CUPNH ;  P22658, HOXF_RHOOP ;  P22320, HOXH_CUPNH ;
DR   P22661, HOXH_RHOOP ;  P22318, HOXU_CUPNH ;  P22659, HOXU_RHOOP ;
DR   P22319, HOXY_CUPNH ;  P22660, HOXY_RHOOP ;
//
ID   1.12.1.3
DE   Hydrogen dehydrogenase (NADP(+)).
AN   NADP-linked hydrogenase.
AN   NADP-reducing hydrogenase.
CA   H(2) + NADP(+) = H(+) + NADPH.
CF   Flavoprotein; Iron-sulfur.
//
ID   1.12.1.4
DE   Hydrogenase (NAD(+), ferredoxin).
AN   Bifurcating (FeFe) hydrogenase.
CA   2 H(2) + NAD(+) + 2 oxidized ferredoxin = 5 H(+) + NADH + 2 reduced
CA   ferredoxin.
CC   -!- The enzyme from Thermotoga maritima contains a (FeFe) cluster
CC       (H-cluster) and iron-sulfur clusters.
CC   -!- It works in the direction evolving hydrogen as a means of eliminating
CC       excess reducing equivalents.
//
ID   1.12.2.1
DE   Cytochrome-c3 hydrogenase.
AN   Cytochrome c3 reductase.
AN   Cytochrome hydrogenase.
AN   H(2):ferricytochrome c3 oxidoreductase.
CA   2 H(2) + ferricytochrome c3 = 4 H(+) + ferrocytochrome c3.
CF   Iron-sulfur; Nickel.
CC   -!- Some forms of the enzyme contain nickel ([NiFe]-hydrogenases) and,
CC       of these, some contain selenocysteine ([NiFeSe]-hydrogenases).
CC   -!- Methylene blue and other acceptors can also be reduced.
DR   P80509, HC3L_THIFE ;  P80510, HC3S_THIFE ;  P18188, PHNL_DESFR ;
DR   P12944, PHNL_DESGI ;  P21852, PHNL_DESVM ;  Q06173, PHNS1_DESVH;
DR   P61429, PHNS2_DESVH;  P13061, PHNS_DESDA ;  P18187, PHNS_DESFR ;
DR   P12943, PHNS_DESGI ;  P13062, PHNS_DESMU ;  P21853, PHNS_DESVM ;
//
ID   1.12.5.1
DE   Hydrogen:quinone oxidoreductase.
AN   Hydrogen-ubiquinone oxidoreductase.
AN   Hydrogen:menaquinone oxidoreductase.
AN   Membrane-bound hydrogenase.
AN   Quinone-reactive Ni/Fe-hydrogenase.
CA   H(2) + menaquinone = menaquinol.
CF   Iron-sulfur; Nickel.
CC   -!- Also catalyzes the reduction of water-soluble quinones (e.g. 2,3-
CC       dimethylnaphthoquinone) or viologen dyes (benzyl viologen or methyl
CC       viologen) by H(2).
CC   -!- Formerly EC 1.12.99.3.
PR   PROSITE; PDOC00400;
DR   P31883, MBHL_WOLSU ;  P31884, MBHS_WOLSU ;
//
ID   1.12.7.1
DE   Transferred entry: 1.12.7.2.
//
ID   1.12.7.2
DE   Ferredoxin hydrogenase.
AN   Bidirectional hydrogenase.
AN   H(2) oxidizing hydrogenase.
AN   H(2) producing hydrogenase.
AN   Hydrogen-lyase.
AN   Hydrogenase.
AN   Hydrogenase (ferredoxin).
AN   Hydrogenase I.
AN   Hydrogenase II.
AN   Hydrogenlyase.
AN   Uptake hydrogenase.
CA   H(2) + 2 oxidized ferredoxin = 2 reduced ferredoxin + 2 H(+).
CF   Iron-sulfur; Nickel.
CC   -!- Can use molecular hydrogen for the reduction of a variety of
CC       substances.
CC   -!- Formerly EC 1.12.1.1, EC 1.12.7.1, EC 1.18.3.1, EC 1.18.99.1,
CC       and EC 1.98.1.1.
PR   PROSITE; PDOC00400;
DR   P29166, PHF1_CLOPA ;  P07598, PHFL_DESVH ;  P13629, PHFL_DESVO ;
DR   P07603, PHFS_DESVH ;  P13628, PHFS_DESVO ;
//
ID   1.12.98.1
DE   Coenzyme F420 hydrogenase.
AN   8-hydroxy-5-deazaflavin-reducing hydrogenase.
AN   Coenzyme F420-dependent hydrogenase.
AN   F420-reducing hydrogenase.
CA   H(2) + coenzyme F420 = reduced coenzyme F420.
CF   FAD; Iron; Nickel.
CC   -!- The enzyme from some sources contains selenocysteine.
CC   -!- The enzyme also reduces the riboflavin analog of F420, flavins and
CC       methylviologen, but to a lesser extent.
CC   -!- The hydrogen acceptor coenzyme F420 is a deazaflavin derivative.
CC   -!- Formerly EC 1.12.99.1.
DR   P80489, FRHA_METBF ;  Q60338, FRHA_METJA ;  P19496, FRHA_METTH ;
DR   Q00390, FRHA_METVO ;  P80490, FRHB_METBF ;  Q60341, FRHB_METJA ;
DR   P19499, FRHB_METTH ;  Q00391, FRHB_METVO ;  P80491, FRHG_METBF ;
DR   Q60340, FRHG_METJA ;  P19498, FRHG_METTH ;  Q00393, FRHG_METVO ;
//
ID   1.12.98.2
DE   5,10-methenyltetrahydromethanopterin hydrogenase.
AN   H(2)-dependent methylene-H(4)MPT dehydrogenase.
AN   H(2)-forming N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase.
AN   Hydrogen:N(5),N(10)-methenyltetrahydromethanopterin oxidoreductase.
AN   N(5),N(10)-methenyltetrahydromethanopterin hydrogenase.
AN   Nonmetal hydrogenase.
CA   H(2) + 5,10-methenyltetrahydromethanopterin = H(+) + 5,10-
CA   methylenetetrahydromethanopterin.
CC   -!- Does not catalyze the reduction of artificial dyes.
CC   -!- Does not by itself catalyze a H(2)/H(+) exchange reaction.
CC   -!- Does not contain nickel or iron-sulfur clusters.
CC   -!- Formerly EC 1.12.99.4.
DR   Q58194, HMD_METJA  ;  Q02394, HMD_METKA  ;  A4G064, HMD_METM5  ;
DR   A6VIB6, HMD_METM7  ;  Q6M0Z1, HMD_METMP  ;  Q50758, HMD_METTF  ;
DR   O27211, HMD_METTH  ;  Q50759, HMD_METTL  ;  P32440, HMD_METTM  ;
DR   P81221, HMD_METTW  ;  Q50840, HMD_METVO  ;  A6URB0, HMD_METVS  ;
DR   P32441, HMD_METWO  ;
//
ID   1.12.98.3
DE   Methanosarcina-phenazine hydrogenase.
AN   Methanophenazine hydrogenase.
AN   Methylviologen-reducing hydrogenase.
CA   H(2) + 2-(2,3-dihydropentaprenyloxy)phenazine =
CA   2-dihydropentaprenyloxyphenazine.
CF   Iron-sulfur; Nickel.
CC   -!- The enzyme from some sources contains selenocysteine.
CC   -!- Formerly EC 1.12.99.2.
//
ID   1.12.99.1
DE   Transferred entry: 1.12.98.1.
//
ID   1.12.99.2
DE   Deleted entry.
//
ID   1.12.99.3
DE   Transferred entry: 1.12.5.1.
//
ID   1.12.99.4
DE   Transferred entry: 1.12.98.2.
//
ID   1.12.99.5
DE   Transferred entry: 1.13.11.47.
//
ID   1.12.99.6
DE   Hydrogenase (acceptor).
AN   H(2) producing hydrogenase.
AN   Hydrogen-lyase.
AN   Hydrogenlyase.
AN   Uptake hydrogenase.
CA   H(2) + A = AH(2).
CF   Iron-sulfur; Nickel.
CC   -!- Uses molecular hydrogen for the reduction of a variety of substances.
DR   P33374, MBHL_ALCHY ;  P18191, MBHL_AZOCH ;  P21949, MBHL_AZOVI ;
DR   P12636, MBHL_BRAJA ;  Q46046, MBHL_CITFR ;  P31891, MBHL_CUPNH ;
DR   P0ACD8, MBHL_ECOLI ;  O33406, MBHL_OLICO ;  P18636, MBHL_RHILV ;
DR   P15284, MBHL_RHOCA ;  P17632, MBHL_RUBGE ;  P0ACD9, MBHL_SHIFL ;
DR   P0ACE1, MBHM_ECO57 ;  P0ACE0, MBHM_ECOLI ;  P0ACE2, MBHM_SHIFL ;
DR   P33375, MBHS_ALCHY ;  P18190, MBHS_AZOCH ;  P21950, MBHS_AZOVI ;
DR   P12635, MBHS_BRAJA ;  Q46045, MBHS_CITFR ;  P31892, MBHS_CUPNH ;
DR   P69740, MBHS_ECOL6 ;  P69739, MBHS_ECOLI ;  O33405, MBHS_OLICO ;
DR   P18637, MBHS_RHILV ;  P15283, MBHS_RHOCA ;  P17633, MBHS_RUBGE ;
DR   Q83RW9, MBHS_SHIFL ;  P69743, MBHT_ECO57 ;  P69742, MBHT_ECOL6 ;
DR   P69741, MBHT_ECOLI ;  P13065, PHSL_DESBA ;  P13066, PHSL_DESNO ;
DR   P13063, PHSS_DESBA ;  P13064, PHSS_DESNO ;
//
ID   1.13.1.1
DE   Transferred entry: 1.13.11.1.
//
ID   1.13.1.2
DE   Transferred entry: 1.13.11.2.
//
ID   1.13.1.3
DE   Transferred entry: 1.13.11.3.
//
ID   1.13.1.4
DE   Transferred entry: 1.13.11.4.
//
ID   1.13.1.5
DE   Transferred entry: 1.13.11.5.
//
ID   1.13.1.6
DE   Transferred entry: 1.13.11.6.
//
ID   1.13.1.7
DE   Deleted entry.
//
ID   1.13.1.8
DE   Transferred entry: 1.13.11.8.
//
ID   1.13.1.9
DE   Transferred entry: 1.13.11.9.
//
ID   1.13.1.10
DE   Transferred entry: 1.13.11.10.
//
ID   1.13.1.11
DE   Transferred entry: 1.13.99.1.
//
ID   1.13.1.12
DE   Transferred entry: 1.13.11.11.
//
ID   1.13.1.13
DE   Transferred entry: 1.13.11.12.
//
ID   1.13.11.1
DE   Catechol 1,2-dioxygenase.
AN   Catechase.
AN   Pyrocatechase.
CA   Catechol + O(2) = cis,cis-muconate.
CF   Iron.
CC   -!- Involved in the metabolism of nitro-aromatic compounds by a strain of
CC       Pseudomonas putida.
CC   -!- Formerly EC 1.13.1.1 and EC 1.99.2.2.
PR   PROSITE; PDOC00079;
DR   O33948, CATA1_ACILW;  O33950, CATA2_ACILW;  P07773, CATA_ACIAD ;
DR   P83715, CATA_ACICA ;  Q43984, CATA_ACIGB ;  P81422, CATA_ACIRA ;
DR   P95607, CATA_RHOOP ;  P86029, HQD2_CANAL ;  P31019, PHEB_PSEUE ;
//
ID   1.13.11.2
DE   Catechol 2,3-dioxygenase.
AN   2,3-pyrocatechase.
AN   Cato2ase.
AN   Metapyrocatechase.
CA   Catechol + O(2) = 2-hydroxymuconate semialdehyde.
CF   Iron.
CC   -!- The enzyme from Alcaligenes sp. strain O-1 has also been shown to
CC       catalyze the reaction: 2,3-dihydroxybenzenesulfonate + O(2) + H(2)O =
CC       2-hydroxymuconate + bisulfite and has been referred to as 2,3-
CC       dihydroxybenzenesulfonate 2,3-dioxygenase.
CC   -!- Further work will be necessary to show whether or not this is a
CC       distinct enzyme.
CC   -!- Formerly EC 1.13.1.2.
PR   PROSITE; PDOC00078;
DR   P54721, CADE_BACSU ;  Q53034, CATA_RHORH ;  P17262, DMPB_PSEUF ;
DR   P17296, MPC2_CUPNE ;  P08127, NAHH_PSEPU ;  P31003, PHEB_GEOSE ;
DR   P06622, XYLE1_PSEPU;  Q04285, XYLE2_PSEPU;  P27887, XYLE_PSEAE ;
//
ID   1.13.11.3
DE   Protocatechuate 3,4-dioxygenase.
AN   Protocatechuate oxygenase.
CA   3,4-dihydroxybenzoate + O(2) = 3-carboxy-cis,cis-muconate.
CF   Iron.
CC   -!- Formerly EC 1.13.1.3 and EC 1.99.2.3.
PR   PROSITE; PDOC00079;
DR   P20371, PCXA_ACIAD ;  P15109, PCXA_BURCE ;  P00436, PCXA_PSEPU ;
DR   P20372, PCXB_ACIAD ;  P15110, PCXB_BURCE ;  P00437, PCXB_PSEPU ;
//
ID   1.13.11.4
DE   Gentisate 1,2-dioxygenase.
AN   Gentisate oxygenase.
AN   Gentisic acid oxidase.
CA   2,5-dihydroxybenzoate + O(2) = maleylpyruvate.
CF   Iron.
CC   -!- Formerly EC 1.13.1.4 and EC 1.99.2.4.
//
ID   1.13.11.5
DE   Homogentisate 1,2-dioxygenase.
AN   Homogentisate oxygenase.
AN   Homogentisic acid oxidase.
AN   Homogentisicase.
CA   Homogentisate + O(2) = 4-maleylacetoacetate.
CF   Iron.
CC   -!- Formerly EC 1.13.1.5 and EC 1.99.2.5.
DR   B9JHZ9, HGD_AGRRK  ;  Q9ZRA2, HGD_ARATH  ;  Q2KYC8, HGD_BORA1  ;
DR   Q7WNZ3, HGD_BORBR  ;  Q7W189, HGD_BORPA  ;  A9I714, HGD_BORPD  ;
DR   Q7VUG2, HGD_BORPE  ;  Q89XH1, HGD_BRAJA  ;  B1YTZ1, HGD_BURA4  ;
DR   Q1BYQ6, HGD_BURCA  ;  B1JWJ3, HGD_BURCC  ;  A0K4Z6, HGD_BURCH  ;
DR   B4ECX5, HGD_BURCJ  ;  Q0BHW3, HGD_BURCM  ;  A9AFM6, HGD_BURM1  ;
DR   A3MMH2, HGD_BURM7  ;  A2S9M1, HGD_BURM9  ;  Q62I34, HGD_BURMA  ;
DR   A1V1U3, HGD_BURMS  ;  A3NYN0, HGD_BURP0  ;  Q3JPA3, HGD_BURP1  ;
DR   Q63RD3, HGD_BURPS  ;  Q39J54, HGD_BURS3  ;  Q2SYQ6, HGD_BURTA  ;
DR   A4JBW6, HGD_BURVG  ;  Q9Y041, HGD_CAEEL  ;  B8H072, HGD_CAUCN  ;
DR   Q9A5B8, HGD_CAUCR  ;  B0T816, HGD_CAUSK  ;  Q0K0L8, HGD_CUPNH  ;
DR   Q46UA4, HGD_CUPPJ  ;  Q54QI4, HGD_DICDI  ;  Q9VKJ0, HGD_DROME  ;
DR   Q00667, HGD_EMENI  ;  Q93099, HGD_HUMAN  ;  Q5X5S2, HGD_LEGPA  ;
DR   A5IBD8, HGD_LEGPC  ;  Q9S4T0, HGD_LEGPH  ;  Q5WX50, HGD_LEGPL  ;
DR   O09173, HGD_MOUSE  ;  Q1D8L9, HGD_MYXXD  ;  Q1QPR8, HGD_NITHX  ;
DR   Q5VRH4, HGD_ORYSJ  ;  Q5RF05, HGD_PONAB  ;  Q48GS7, HGD_PSE14  ;
DR   A6V6F5, HGD_PSEA7  ;  B7VA96, HGD_PSEA8  ;  Q02LF6, HGD_PSEAB  ;
DR   Q9X4G0, HGD_PSEAE  ;  Q1I500, HGD_PSEE4  ;  Q4KI35, HGD_PSEF5  ;
DR   A5W8Z1, HGD_PSEP1  ;  Q3KHV3, HGD_PSEPF  ;  B0KGU6, HGD_PSEPG  ;
DR   Q88E47, HGD_PSEPK  ;  B1J390, HGD_PSEPW  ;  Q87Z79, HGD_PSESM  ;
DR   Q4ZR64, HGD_PSEU2  ;  B2UJ73, HGD_RALPJ  ;  Q8XRZ0, HGD_RALSO  ;
DR   B3PWZ9, HGD_RHIE6  ;  Q2K9E5, HGD_RHIEC  ;  Q1MI52, HGD_RHIL3  ;
DR   Q983J4, HGD_RHILO  ;  B5ZZA8, HGD_RHILW  ;  Q9X4F5, HGD_RHIME  ;
DR   C3M930, HGD_RHISN  ;  Q2J1P2, HGD_RHOP2  ;  Q07T66, HGD_RHOP5  ;
DR   Q6N0T9, HGD_RHOPA  ;  Q21AX5, HGD_RHOPB  ;  Q13CD3, HGD_RHOPS  ;
DR   B3QB98, HGD_RHOPT  ;  A6UDD3, HGD_SINMW  ;  Q828S5, HGD_STRAW  ;
DR   Q9S2B5, HGD_STRCO  ;  Q8PQ74, HGD_XANAC  ;  Q3BYE8, HGD_XANC5  ;
DR   Q4UZI9, HGD_XANC8  ;  Q8PDA2, HGD_XANCP  ;  Q2NYM7, HGD_XANOM  ;
DR   B2SM18, HGD_XANOP  ;  Q5GVE9, HGD_XANOR  ;
//
ID   1.13.11.6
DE   3-hydroxyanthranilate 3,4-dioxygenase.
AN   3-hydroxyanthranilate oxygenase.
AN   3-hydroxyanthranilic acid dioxygenase.
AN   3-hydroxyanthranilic acid oxidase.
CA   3-hydroxyanthranilate + O(2) = 2-amino-3-carboxymuconate semialdehyde.
CF   Iron.
CC   -!- The product of the reaction spontaneously rearrange to quinolinic
CC       acid (quin).
CC   -!- Formerly EC 1.13.1.6.
DR   A1C408, 3HAO1_ASPCL;  B0Y9Z9, 3HAO1_ASPFC;  Q4WCF1, 3HAO1_ASPFU;
DR   Q2UHT9, 3HAO1_ASPOR;  A1C874, 3HAO2_ASPCL;  B0XVP0, 3HAO2_ASPFC;
DR   Q4WZC3, 3HAO2_ASPFU;  Q2UB88, 3HAO2_ASPOR;  Q75CP6, 3HAO_ASHGO ;
DR   A2R8S7, 3HAO_ASPNC ;  Q0D1U6, 3HAO_ASPTN ;  A0RD64, 3HAO_BACAH ;
DR   Q739J0, 3HAO_BACC1 ;  C1ERL1, 3HAO_BACC3 ;  Q0VCA8, 3HAO_BOVIN ;
DR   B4EFS7, 3HAO_BURCJ ;  B2T2S5, 3HAO_BURPP ;  Q39LI1, 3HAO_BURS3 ;
DR   Q60W34, 3HAO_CAEBR ;  Q19341, 3HAO_CAEEL ;  Q59K86, 3HAO_CANAL ;
DR   Q2HD63, 3HAO_CHAGB ;  Q1E5I0, 3HAO_COCIM ;  P0CL87, 3HAO_CRYNB ;
DR   P0CL86, 3HAO_CRYNJ ;  Q46PT7, 3HAO_CUPPJ ;  Q5U3F8, 3HAO_DANRE ;
DR   Q54S02, 3HAO_DICDI ;  P46952, 3HAO_HUMAN ;  Q28SE8, 3HAO_JANSC ;
DR   A5E0Z9, 3HAO_LODEL ;  A4REV8, 3HAO_MAGO7 ;  Q78JT3, 3HAO_MOUSE ;
DR   A7RIT9, 3HAO_NEMVE ;  A1DB76, 3HAO_NEOFI ;  Q7SDX3, 3HAO_NEUCR ;
DR   A6X798, 3HAO_OCHA4 ;  A5DLW3, 3HAO_PICGU ;  A3LP72, 3HAO_PICST ;
DR   B2AAJ5, 3HAO_PODAN ;  Q83V26, 3HAO_PSEFL ;  Q1LCS4, 3HAO_RALME ;
DR   P46953, 3HAO_RAT   ;  B1KJM7, 3HAO_SHEWM ;  Q5LSJ4, 3HAO_SILPO ;
DR   Q4P2Q7, 3HAO_USTMA ;  Q8PM31, 3HAO_XANAC ;  Q3BV37, 3HAO_XANC5 ;
DR   Q4UT95, 3HAO_XANC8 ;  B0RUZ7, 3HAO_XANCB ;  Q8PAD0, 3HAO_XANCP ;
DR   Q2P320, 3HAO_XANOM ;  Q5H043, 3HAO_XANOR ;  Q6P7I0, 3HAO_XENLA ;
DR   Q6DIZ0, 3HAO_XENTR ;  Q6CFX1, 3HAO_YARLI ;  P47096, 3HAO_YEAST ;
//
ID   1.13.11.7
DE   Deleted entry.
//
ID   1.13.11.8
DE   Protocatechuate 4,5-dioxygenase.
AN   Protocatechuate 4,5-oxygenase.
CA   Protocatechuate + O(2) = 4-carboxy-2-hydroxymuconate semialdehyde.
CF   Iron.
CC   -!- Formerly EC 1.13.1.8.
DR   P22635, PCYA_PSEPA ;  P22636, PCYB_PSEPA ;
//
ID   1.13.11.9
DE   2,5-dihydroxypyridine 5,6-dioxygenase.
AN   2,5-dihydroxypyridine oxygenase.
AN   Pyridine-2,5-diol dioxygenase.
CA   2,5-dihydroxypyridine + O(2) = N-formylmaleamate + H(+).
CF   Iron.
CC   -!- Formerly EC 1.13.1.9.
//
ID   1.13.11.10
DE   7,8-dihydroxykynurenate 8,8a-dioxygenase.
AN   7,8-dihydroxykynurenate oxygenase.
CA   7,8-dihydroxykynurenate + O(2) = 5-(3-carboxy-3-oxopropenyl)-4,6-
CA   dihydroxypyridine-2-carboxylate.
CF   Iron.
CC   -!- Formerly EC 1.13.1.10.
//
ID   1.13.11.11
DE   Tryptophan 2,3-dioxygenase.
AN   Indolamine 2,3-dioxygenase.
AN   Indoleamine 2,3-dioxygenase.
AN   L-tryptophan 2,3-dioxygenase.
AN   L-tryptophan pyrrolase.
AN   Tryptamin 2,3-dioxygenase.
AN   Tryptamine 2,3-dioxygenase.
AN   Tryptophan oxygenase.
AN   Tryptophan peroxidase.
AN   Tryptophan pyrrolase.
AN   Tryptophanase.
CA   L-tryptophan + O(2) = N-formyl-L-kynurenine.
CF   Heme.
CC   -!- Catalyzes, together with EC 1.13.11.52, the first and rate-limiting
CC       step in the kynurenine pathway, the major pathway of tryptophan
CC       metabolism.
CC   -!- Specific for tryptophan as substrate, but is far more active with
CC       L-tryptophan than with D-tryptophan.
CC   -!- Formerly EC 1.11.1.4 and EC 1.13.1.12.
DR   A7MBU6, T23OA_DANRE;  Q7SY53, T23OB_DANRE;  Q17P71, T23O_AEDAE ;
DR   B4RUH2, T23O_ALTMD ;  Q2IEC3, T23O_ANADE ;  B4UMQ6, T23O_ANASK ;
DR   O77457, T23O_ANOGA ;  A0JUV5, T23O_ARTS2 ;  A0REX0, T23O_BACAH ;
DR   Q81PQ0, T23O_BACAN ;  Q736W5, T23O_BACC1 ;  Q63AJ2, T23O_BACCZ ;
DR   Q6HHX9, T23O_BACHK ;  A9VHP7, T23O_BACWK ;  Q6MM37, T23O_BDEBA ;
DR   Q7WHE8, T23O_BORBR ;  Q7W9B7, T23O_BORPA ;  Q7VYS6, T23O_BORPE ;
DR   Q2KIQ5, T23O_BOVIN ;  Q89MN4, T23O_BRAJA ;  A5EQH6, T23O_BRASB ;
DR   A4YND6, T23O_BRASO ;  B1YVH2, T23O_BURA4 ;  Q1BU34, T23O_BURCA ;
DR   B1JXI9, T23O_BURCC ;  A0KA02, T23O_BURCH ;  B4E9J1, T23O_BURCJ ;
DR   Q0BCE0, T23O_BURCM ;  A9AGH1, T23O_BURM1 ;  A3MHE1, T23O_BURM7 ;
DR   A2S924, T23O_BURM9 ;  Q62M99, T23O_BURMA ;  A1V193, T23O_BURMS ;
DR   A3NS55, T23O_BURP0 ;  Q3JVD8, T23O_BURP1 ;  A3N6H2, T23O_BURP6 ;
DR   B2SY86, T23O_BURPP ;  Q63WP5, T23O_BURPS ;  Q39DG2, T23O_BURS3 ;
DR   A8X7X9, T23O_CAEBR ;  Q09474, T23O_CAEEL ;  Q9A4E8, T23O_CAUCR ;
DR   Q0K7X7, T23O_CUPNH ;  Q55DB4, T23O_DICDI ;  B3MQP7, T23O_DROAN ;
DR   B3NVC6, T23O_DROER ;  B4JKK1, T23O_DROGR ;  P20351, T23O_DROME ;
DR   B4L629, T23O_DROMO ;  B4H4U3, T23O_DROPE ;  Q29I03, T23O_DROPS ;
DR   B4IDV8, T23O_DROSE ;  Q24630, T23O_DROSI ;  B4M818, T23O_DROVI ;
DR   B4MSH7, T23O_DROWI ;  B4PYW0, T23O_DROYA ;  Q2N5X1, T23O_ERYLH ;
DR   B1YHD4, T23O_EXIS2 ;  A4IT59, T23O_GEOTN ;  A9B4J6, T23O_HERA2 ;
DR   P48775, T23O_HUMAN ;  A6W961, T23O_KINRD ;  Q2LD53, T23O_MAYDE ;
DR   P48776, T23O_MOUSE ;  Q1CVR6, T23O_MYXXD ;  A1SG03, T23O_NOCSJ ;
DR   A1VRP1, T23O_POLNA ;  Q126P7, T23O_POLSJ ;  Q02N70, T23O_PSEAB ;
DR   Q9I0Q7, T23O_PSEAE ;  Q4KIP3, T23O_PSEF5 ;  Q84HF6, T23O_PSEFL ;
DR   Q1LK00, T23O_RALME ;  B2U7J7, T23O_RALPJ ;  Q8XRY7, T23O_RALSO ;
DR   P21643, T23O_RAT   ;  Q0SFS2, T23O_RHOSR ;  A4FH01, T23O_SACEN ;
DR   A8GG83, T23O_SERP5 ;  B1KJM2, T23O_SHEWM ;  Q5LKH2, T23O_SILPO ;
DR   Q1GEF8, T23O_SILST ;  A9FU01, T23O_SORC5 ;  B2FKN7, T23O_STRMK ;
DR   Q95NN1, T23O_TRICA ;  Q8PQ80, T23O_XANAC ;  Q3BYF4, T23O_XANC5 ;
DR   Q4UZJ5, T23O_XANC8 ;  B0RMW5, T23O_XANCB ;  Q8PDA8, T23O_XANCP ;
DR   Q2NYM2, T23O_XANOM ;  B2SM13, T23O_XANOP ;  Q5GVE4, T23O_XANOR ;
DR   Q5U4U6, T23O_XENLA ;  Q5EBG2, T23O_XENTR ;
//
ID   1.13.11.12
DE   Linoleate 13S-lipoxygenase.
AN   13-lipoperoxidase.
AN   13-lipoxidase.
AN   13-lipoxidase.
AN   Carotene oxidase.
AN   Lipoperoxidase.
AN   Lipoxidase.
CA   Linoleate + O(2) = (9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate.
CF   Iron.
CC   -!- A common plant lipoxygenase that oxidizes linoleate and alpha-
CC       linolenate, the two most common polyunsaturated fatty acids in
CC       plants, by inserting molecular oxygen at the C(13) position with (S)-
CC       configuration.
CC   -!- This enzyme produces precursors for several important compounds,
CC       including the plant hormone jasmonic acid.
CC   -!- EC 1.13.11.58 catalyzes a similar reaction at the second available
CC       position of these fatty acids.
CC   -!- Formerly EC 1.13.1.13 and EC 1.99.2.1.
PR   PROSITE; PDOC00077;
DR   P93184, LOX21_HORVU;  O24370, LOX21_SOLTU;  Q8GSM3, LOX22_HORVU;
DR   Q8GSM2, LOX23_HORVU;  P38418, LOX2_ARATH ;  O24371, LOX31_SOLTU;
DR   Q9LNR3, LOX3_ARATH ;  Q9FNX8, LOX4_ARATH ;  Q7XV13, LOX5_ORYSJ ;
DR   Q9CAG3, LOX6_ARATH ;  Q8H016, LOX6_ORYSJ ;  P27480, LOXA_PHAVU ;
DR   P27481, LOXB_PHAVU ;  P38419, LOXC1_ORYSJ;  Q84YK8, LOXC2_ORYSJ;
//
ID   1.13.11.13
DE   Ascorbate 2,3-dioxygenase.
CA   Ascorbate + O(2) + H(2)O = oxalate + threonate.
CF   Iron.
//
ID   1.13.11.14
DE   2,3-dihydroxybenzoate 3,4-dioxygenase.
AN   2,3-dihydroxybenzoic oxygenase.
AN   o-pyrocatechuate oxygenase.
CA   2,3-dihydroxybenzoate + O(2) = 3-carboxy-2-hydroxymuconate semialdehyde.
//
ID   1.13.11.15
DE   3,4-dihydroxyphenylacetate 2,3-dioxygenase.
AN   Homoprotocatechuate 2,3-dioxygenase.
AN   HPC dioxygenase.
CA   3,4-dihydroxyphenylacetate + O(2) = 2-hydroxy-5-carboxymethylmuconate
CA   semialdehyde.
CF   Iron.
DR   Q05353, HPCB_ECOLX ;
//
ID   1.13.11.16
DE   3-carboxyethylcatechol 2,3-dioxygenase.
AN   2,3-dihydroxy-beta-phenylpropionate oxygenase.
AN   2,3-dihydroxyphenylpropanoate 1,2-dioxygenase.
AN   2,3-dihydroxyphenylpropionate 1,2-dioxygenase.
CA   3-(2,3-dihydroxyphenyl)propanoate + O(2) = 2-hydroxy-6-oxonona-2,4-diene-
CA   1,9-dioate.
CF   Iron.
DR   Q47HM4, MHPB1_DECAR;  Q400K4, MHPB1_PSEPU;  Q47GC9, MHPB2_DECAR;
DR   Q9F9U5, MHPB2_PSEPU;  A1K6Y7, MHPB_AZOSB ;  C1DRI2, MHPB_AZOVD ;
DR   B2JQV7, MHPB_BURP8 ;  A4JPY0, MHPB_BURVG ;  Q13QH9, MHPB_BURXL ;
DR   Q9S157, MHPB_COMTE ;  P17295, MHPB_CUPNE ;  Q476N0, MHPB_CUPPJ ;
DR   A7ZI95, MHPB_ECO24 ;  B7L504, MHPB_ECO55 ;  P0ABS0, MHPB_ECO57 ;
DR   B5Z2Q3, MHPB_ECO5E ;  B7NK07, MHPB_ECO7I ;  B7MPB5, MHPB_ECO81 ;
DR   B7M2Z6, MHPB_ECO8A ;  B1XBJ5, MHPB_ECODH ;  A7ZWZ5, MHPB_ECOHS ;
DR   P0ABR9, MHPB_ECOLI ;  B7N8Q5, MHPB_ECOLU ;  B6HZX4, MHPB_ECOSE ;
DR   B1LIN3, MHPB_ECOSM ;  B5XQJ0, MHPB_KLEP3 ;  A6TAC8, MHPB_KLEP7 ;
DR   A4T8B7, MHPB_MYCGI ;  Q742Z0, MHPB_MYCPA ;  A0R1T3, MHPB_MYCS2 ;
DR   A3Q338, MHPB_MYCSJ ;  A1UJP3, MHPB_MYCSK ;  Q1B5E3, MHPB_MYCSS ;
DR   A0PL52, MHPB_MYCUA ;  A1TCX1, MHPB_MYCVP ;  Q7N4V6, MHPB_PHOLL ;
DR   O05146, MHPB_RHOGO ;  Q762H5, MHPB_RHORH ;  Q9KH19, MHPB_RHOSO ;
DR   Q0SJD2, MHPB_RHOSR ;  Q3Z586, MHPB_SHISS ;  A7IDU0, MHPB_XANP2 ;
//
ID   1.13.11.17
DE   Indole 2,3-dioxygenase.
AN   Indole oxidase.
CA   Indole + O(2) = 2-formylaminobenzaldehyde.
CF   Copper; Flavoprotein.
CC   -!- The enzyme from Jasminum is a flavoprotein containing copper,
CC       and forms anthranilate as the final product.
CC   -!- One enzyme from Tecoma stans is also a flavoprotein containing copper
CC       and uses three atoms of oxygen per molecule of indole, to form
CC       anthranil (3,4-benzisoxazole).
CC   -!- A second enzyme from Tecoma stans, which is not a flavoprotein, uses
CC       four atoms of oxygen and forms anthranilate as the final product.
//
ID   1.13.11.18
DE   Sulfur dioxygenase.
AN   Sulfur oxygenase.
CA   Sulfur + O(2) + H(2)O = sulfite + 2 H(+).
CF   Iron.
CC   -!- Glutathione (GSH) plays a catalytic role in elemental sulfur
CC       activation, but is not consumed during the enzymic reaction.
CC   -!- GSH and elemental sulfur react non-enzymically to yield
CC       S-sulfanylglutathione and it is only in this form that the sulfur can
CC       be oxidized to yield sulfite.
CC   -!- The sulfite can be further converted into sulfate, thiosulfate or
CC       S-sulfoglutathione (GSSO(3)(-)) non-enzymically.
//
ID   1.13.11.19
DE   Cysteamine dioxygenase.
AN   Cysteamine oxygenase.
AN   Persulfurase.
CA   2-aminoethanethiol + O(2) = hypotaurine.
CF   Iron.
CC   -!- Involved in the biosynthesis of taurine.
CC   -!- Requires catalytic amounts of a cofactor-like compound, such as
CC       sulfur, sufide, selenium or methylene blue for maximal activity.
CC   -!- 3-aminopropanethiol (homocysteamine) and 2-mercaptoethanol can also
CC       act as substrates, but glutathione, cysteine, and cysteine ethyl- and
CC       methyl esters are not good substrates.
DR   Q556I2, AEDO_DICDI ;  Q96SZ5, AEDO_HUMAN ;  Q6PDY2, AEDO_MOUSE ;
//
ID   1.13.11.20
DE   Cysteine dioxygenase.
CA   L-cysteine + O(2) = 3-sulfinoalanine.
CF   Iron; NAD(P)H.
DR   Q3SZU4, CDO1_BOVIN ;  Q20893, CDO1_CAEEL ;  Q6NWZ9, CDO1_DANRE ;
DR   Q16878, CDO1_HUMAN ;  P60334, CDO1_MOUSE ;  Q5RBQ7, CDO1_PONAB ;
DR   P21816, CDO1_RAT   ;  O32085, CDOA_BACSU ;  Q5RLY7, CDO_AJECG  ;
DR   Q60TI7, CDO_CAEBR  ;  Q9U8F1, CDO_SCHJA  ;
//
ID   1.13.11.21
DE   Transferred entry: 1.14.99.36.
//
ID   1.13.11.22
DE   Caffeate 3,4-dioxygenase.
CA   3,4-dihydroxy-trans-cinnamate + O(2) = 3-(2-carboxyethenyl)-cis,cis-
CA   muconate.
//
ID   1.13.11.23
DE   2,3-dihydroxyindole 2,3-dioxygenase.
CA   2,3-dihydroxyindole + O(2) = anthranilate + CO(2).
//
ID   1.13.11.24
DE   Quercetin 2,3-dioxygenase.
CA   Quercetin + O(2) = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate +
CA   CO + H(+).
CF   Iron or copper.
CC   -!- Quercetin is a flavonol (5,7,3',4'-tetrahydroxyflavonol).
DR   O00625, PIR_HUMAN  ;  Q9D711, PIR_MOUSE  ;  Q5M827, PIR_RAT    ;
DR   Q7SIC2, QDOI_ASPJA ;  P42106, QDOI_BACSU ;  Q9I4D3, Y1205_PSEAE;
DR   Q9I4C8, Y1210_PSEAE;  Q9XBR7, Y1337_ZYMMO;  Q9HLU2, Y133_THEAC ;
DR   Q9CKD7, Y1685_PASMU;  P73623, Y1773_SYNY3;  P65724, Y181_MYCTU ;
DR   P65725, Y187_MYCBO ;  Q9I163, Y2418_PSEAE;  Q9HZ00, Y3240_PSEAE;
DR   Q9KKY1, Y3769_VIBCH;  P58116, YHHW_ECO57 ;  P46852, YHHW_ECOLI ;
//
ID   1.13.11.25
DE   3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-
DE   dioxygenase.
AN   3-alkylcatechol 2,3-dioxygenase.
AN   Steroid 4,5-dioxygenase.
CA   3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + O(2) =
CA   3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate.
CF   Iron.
CC   -!- Also acts on 3-isopropylcatechol and 3-tert-butyl-5-methylcatechol.
//
ID   1.13.11.26
DE   Peptide-tryptophan 2,3-dioxygenase.
AN   Pyrrolooxygenase.
AN   Tryptophan pyrrolooxygenase.
CA   Peptide tryptophan + O(2) = peptide formylkynurenine.
CC   -!- Also acts on tryptophan.
//
ID   1.13.11.27
DE   4-hydroxyphenylpyruvate dioxygenase.
AN   4-hydroxyphenylpyruvate hydroxylase.
AN   p-hydroxyphenylpyruvate dioxygenase.
AN   p-hydroxyphenylpyruvate oxidase.
CA   4-hydroxyphenylpyruvate + O(2) = homogentisate + CO(2).
CF   Iron.
CC   -!- Formerly EC 1.14.2.2 and EC 1.99.1.14.
DR   Q4WHU1, HPPD1_ASPFU;  Q4WPV8, HPPD2_ASPFU;  P93836, HPPD_ARATH ;
DR   Q5EA20, HPPD_BOVIN ;  Q60Y65, HPPD_CAEBR ;  Q22633, HPPD_CAEEL ;
DR   Q1E803, HPPD_COCIM ;  P0CW94, HPPD_COCP7 ;  E9CWP5, HPPD_COCPS ;
DR   Q6TGZ5, HPPD_DANRE ;  O23920, HPPD_DAUCA ;  Q76NV5, HPPD_DICDI ;
DR   O48604, HPPD_HORVU ;  P32754, HPPD_HUMAN ;  Q96X22, HPPD_MAGO7 ;
DR   P49429, HPPD_MOUSE ;  O42764, HPPD_MYCGR ;  Q872T7, HPPD_NEUCR ;
DR   Q02110, HPPD_PIG   ;  Q9I576, HPPD_PSEAE ;  P80064, HPPD_PSEUJ ;
DR   P32755, HPPD_RAT   ;  Q9ARF9, HPPD_SOLSC ;  Q53586, HPPD_STRAW ;
DR   Q9S2F4, HPPD_STRCO ;  Q27203, HPPD_TETTH ;  Q5BKL0, HPPD_XENTR ;
DR   Q6CDR5, HPPD_YARLI ;  P69053, LLY_LEGPC  ;  Q5ZT84, LLY_LEGPH  ;
//
ID   1.13.11.28
DE   2,3-dihydroxybenzoate 2,3-dioxygenase.
CA   2,3-dihydroxybenzoate + O(2) = 2-carboxy-cis,cis-muconate.
CC   -!- Also acts, more slowly, with 2,3-dihydroxy-4-methylbenzoate and 2,3-
CC       dihydroxy-4-isopropylbenzoate.
//
ID   1.13.11.29
DE   Stizolobate synthase.
CA   3,4-dihydroxy-L-phenylalanine + O(2) = 4-(L-alanin-3-yl)-2-hydroxy-
CA   cis,cis-muconate 6-semialdehyde.
CF   Zinc.
CC   -!- The intermediate product undergoes ring closure and oxidation, with
CC       NAD(P)(+) as acceptor, to stizolobic acid.
//
ID   1.13.11.30
DE   Stizolobinate synthase.
CA   3,4-dihydroxy-L-phenylalanine + O(2) = 5-(L-alanin-3-yl)-2-hydroxy-
CA   cis,cis-muconate 6-semialdehyde.
CF   Zinc.
CC   -!- The intermediate product undergoes ring closure and oxidation, with
CC       NAD(P)(+) as acceptor, to stizolobinic acid.
//
ID   1.13.11.31
DE   Arachidonate 12-lipoxygenase.
AN   12-lipoxygenase.
CA   Arachidonate + O(2) = (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-
CA   5,8,10,14-tetraenoate.
CF   Iron.
CC   -!- The product is rapidly reduced to the corresponding 12S-hydroxy
CC       compound.
PR   PROSITE; PDOC00077;
DR   P27479, LOX12_BOVIN;  P18054, LOX12_HUMAN;  P39655, LOX12_MOUSE;
DR   P16469, LOX12_PIG  ;  O19043, LOX12_RABIT;  P55249, LX12E_MOUSE;
DR   P39654, LX12L_MOUSE;  Q02759, LX12L_RAT  ;
//
ID   1.13.11.32
DE   Transferred entry: 1.13.12.16.
//
ID   1.13.11.33
DE   Arachidonate 15-lipoxygenase.
AN   15-lipoxygenase.
AN   Arachidonate omega(6) lipoxygenase.
CA   Arachidonate + O(2) = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-
CA   5,8,11,13-tetraenoate.
CF   Iron.
CC   -!- The product is rapidly converted to the corresponding 15S-hydroxy
CC       compound.
PR   PROSITE; PDOC00077;
DR   P16050, LOX15_HUMAN;  Q5RBE8, LOX15_PONAB;  P12530, LOX15_RABIT;
DR   Q9I4G8, LOXA_PSEAE ;  O15296, LX15B_HUMAN;  O35936, LX15B_MOUSE;
DR   Q8K4F2, LX15B_RAT  ;
//
ID   1.13.11.34
DE   Arachidonate 5-lipoxygenase.
AN   5-Delta-lipoxygenase.
AN   5-lipoxygenase.
AN   Arachidonic 5-lipoxygenase.
AN   Arachidonic acid 5-lipoxygenase.
AN   C-5-lipoxygenase.
AN   Delta(5)-lipoxygenase.
AN   Leukotriene-A(4) synthase.
AN   LTA synthase.
CA   Arachidonate + O(2) = leukotriene A(4) + H(2)O.
CF   Iron.
PR   PROSITE; PDOC00077;
DR   P09917, LOX5_HUMAN ;  P51399, LOX5_MESAU ;  P48999, LOX5_MOUSE ;
DR   P12527, LOX5_RAT   ;
//
ID   1.13.11.35
DE   Pyrogallol 1,2-oxygenase.
CA   1,2,3-trihydroxybenzene + O(2) = (Z)-5-oxohex-2-enedioate.
//
ID   1.13.11.36
DE   Chloridazon-catechol dioxygenase.
CA   5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone + O(2) =
CA   5-amino-4-chloro-2-(2-hydroxymuconoyl)-3(2H)-pyridazinone.
CF   Iron.
CC   -!- Involved in the breakdown of the herbicide chloridazon.
CC   -!- Not identical with EC 1.13.11.1, EC 1.13.11.2 or EC 1.13.11.5.
//
ID   1.13.11.37
DE   Hydroxyquinol 1,2-dioxygenase.
CA   Benzene-1,2,4-triol + O(2) = 3-hydroxy-cis,cis-muconate.
CF   Iron.
CC   -!- The product isomerizes to 2-maleylacetate (cis-hexenedioate).
CC   -!- Highly specific; catechol and pyrogallol are acted on at less than 1%
CC       of the rate at which hydroxyquinol is oxidized.
DR   Q5PXQ6, CHQB_NOCSI ;
//
ID   1.13.11.38
DE   1-hydroxy-2-naphthoate 1,2-dioxygenase.
AN   1-hydroxy-2-naphthoate-degrading enzyme.
AN   1-hydroxy-2-naphthoic acid dioxygenase.
CA   1-hydroxy-2-naphthoate + O(2) = (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-
CA   enoate.
CF   Iron.
CC   -!- Involved, with EC 4.1.2.34, in the metabolism of phenanthrene in
CC       bacteria.
//
ID   1.13.11.39
DE   Biphenyl-2,3-diol 1,2-dioxygenase.
AN   2,3-dihydroxybiphenyl dioxygenase.
CA   Biphenyl-2,3-diol + O(2) = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate.
CF   Manganese or iron.
CC   -!- This enzyme participates in the degradation pathway of biphenyl and
CC       PCB (poly chlorinated biphenyls), and catalyzes the first ring
CC       cleavage step by incorporating two oxygen atoms into the catechol
CC       ring formed by EC 1.3.1.56.
CC   -!- The enzyme from the bacterium Burkholderia xenovorans LB400 can also
CC       process catechol, 3-methylcatechol, and 4-methylcatechol, but less
CC       efficiently.
CC   -!- The enzyme from the carbazole-degrader Pseudomonas resinovorans
CC       strain CA10 also accepts 2'-aminobiphenyl-2,3-diol.
CC   -!- The enzyme from Ralstonia sp. SBUG 290 can also accept 1,2-
CC       dihydroxydibenzofuran and 1,2-dihydroxynaphthalene.
CC   -!- The enzyme is strongly inhibited by the substrate.
CC   -!- Not identical with EC 1.13.11.2.
PR   PROSITE; PDOC00078;
DR   P47231, BPHC1_RHOGO;  P47232, BPHC2_RHOGO;  P47233, BPHC3_RHOGO;
DR   Q8GR45, BPHC_BACPJ ;  P47228, BPHC_BURXL ;  P11122, BPHC_PSEPA ;
DR   P08695, BPHC_PSEPS ;  P17297, BPHC_PSES1 ;
//
ID   1.13.11.40
DE   Arachidonate 8-lipoxygenase.
AN   8-lipoxygenase.
CA   Arachidonate + O(2) = (5Z,9E,11Z,14Z)-(8R)-8-hydroperoxyicosa-5,9,11,14-
CA   tetraenoate.
CF   Iron.
CC   -!- An enzyme from the coral Pseudoplexaura porosa.
PR   PROSITE; PDOC00077;
DR   O16025, AOSL_PLEHO ;
//
ID   1.13.11.41
DE   2,4'-dihydroxyacetophenone dioxygenase.
CA   2,4'-dihydroxyacetophenone + O(2) = 4-hydroxybenzoate + formate.
//
ID   1.13.11.42
DE   Deleted entry.
//
ID   1.13.11.43
DE   Lignostilbene alpha-beta-dioxygenase.
CA   1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O(2) = 2 vanillin.
CF   Iron.
CC   -!- The enzyme catalyzes oxidative cleavage of the interphenyl double
CC       bond in the synthetic substrate and lignin-derived stilbenes.
CC   -!- It is responsible for the degradation of a diarylpropane-type
CC       structure in lignin.
//
ID   1.13.11.44
DE   Linoleate diol synthase.
AN   Linoleate (8R)-dioxygenase.
AN   Linoleate 8-dioxygenase.
CA   Linoleate + O(2) = (9Z,12Z)-(7S,8S)-dihydroxyoctadeca-9,12-dienoate.
CF   Heme.
CC   -!- Oleate and linolenate are also substrates, whereas stearate,
CC       elaidate, gamma-linolenate, arachidonate and eicosapentaenate are
CC       not.
CC   -!- This enzyme differs from EC 1.13.11.12 because it catalyzes the
CC       formation of a hydroperoxide without affecting the double bonds of
CC       the substrate.
DR   Q9UUS2, LIDS_GAEGR ;
//
ID   1.13.11.45
DE   Linoleate 11-lipoxygenase.
AN   Linoleate dioxygenase.
AN   Manganese lipoxygenase.
CA   Linoleate + O(2) = (9Z,12Z)-(11S)-11-hydroperoxyoctadeca-9,12-dienoate.
CC   -!- The product (9Z,12Z)-(11S)-11-hydroperoxyoctadeca-9,12-dienoate,
CC       is converted, more slowly, into (9Z,11E)-(13R)-13-
CC       hydroperoxyoctadeca-9,11-dienoate.
CC   -!- The enzyme from the fungus Gaeumannomyces graminis requires Mn(2+).
CC   -!- It also acts on alpha-linolenate, whereas gamma-linolenate is a poor
CC       substrate.
CC   -!- Oleate and arachidonate are not substrates.
//
ID   1.13.11.46
DE   4-hydroxymandelate synthase.
AN   4-hydroxyphenylpyruvate dioxygenase II.
CA   4-hydroxyphenylpyruvate + O(2) = 4-hydroxymandelate + CO(2).
CF   Iron.
CC   -!- Involved in the biosynthesis of the vancomycin group of glycopeptide
CC       antibiotics.
//
ID   1.13.11.47
DE   3-hydroxy-4-oxoquinoline 2,4-dioxygenase.
AN   (1H)-3-hydroxy-4-oxoquinoline 2,4-dioxygenase.
AN   3-hydroxy-4(1H)-one, 2,4-dioxygenase.
AN   3-hydroxy-4-oxo-1,4-dihydroquinoline 2,4-dioxygenase.
AN   Quinoline-3,4-diol 2,4-dioxygenase.
CA   3-hydroxy-1H-quinolin-4-one + O(2) = N-formylanthranilate + CO.
CC   -!- Does not contain a metal center or organic cofactor.
CC   -!- Fission of two C-C bonds: 2,4-dioxygenolytic cleavage with
CC       concomitant release of carbon monoxide.
CC   -!- The enzyme from Pseudomonas putida is highly specific for this
CC       substrate.
CC   -!- Formerly EC 1.12.99.5 and EC 1.13.99.5.
//
ID   1.13.11.48
DE   3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase.
AN   (1H)-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase.
CA   3-hydroxy-2-methyl-1H-quinolin-4-one + O(2) = N-acetylanthranilate + CO.
CC   -!- Does not contain a metal center or organic cofactor.
CC   -!- Fission of two C-C bonds: 2,4-dioxygenolytic cleavage with
CC       concomitant release of carbon monoxide.
CC   -!- The enzyme from Arthrobacter sp. can also act on 3-hydroxy-4-
CC       oxoquinoline, forming N-formylanthranilate and CO (cf.
CC       EC 1.13.11.47), but more slowly.
//
ID   1.13.11.49
DE   Chlorite O(2)-lyase.
AN   Chlorite dismutase.
CA   Chloride + O(2) = chlorite.
CF   Iron; Protoheme IX.
CC   -!- Reaction occurs in the reverse direction in chlorate- and
CC       perchlorate-reducing bacteria.
CC   -!- There is no activity when chlorite is replaced by hydrogen peroxide,
CC       perchlorate, chlorate or nitrite.
CC   -!- The term 'chlorite dismutase' is misleading as the reaction does not
CC       involve dismutation/disproportionation.
//
ID   1.13.11.50
DE   Acetylacetone-cleaving enzyme.
AN   Acetylacetone dioxygenase.
AN   Diketone cleaving dioxygenase.
AN   Diketone cleaving enzyme.
CA   Pentane-2,4-dione + O(2) = acetate + 2-oxopropanal.
CF   Iron.
CC   -!- Forms the first step in the acetylacetone degradation pathway of
CC       Acinetobacter johnsonii.
CC   -!- While acetylacetone is by far the best substrate, heptane-3,5-dione,
CC       octane-2,4-dione, 2-acetylcyclohexanone and ethyl acetoacetate can
CC       also act as substrates.
DR   Q8GNT2, DKE1_ACIJO ;
//
ID   1.13.11.51
DE   9-cis-epoxycarotenoid dioxygenase.
AN   NCED.
AN   Nine-cis-epoxycarotenoid dioxygenase.
AN   VP14.
CA   (1) A 9-cis-epoxycarotenoid + O(2) = 2-cis,4-trans-xanthoxin + a 12'-apo-
CA   carotenal.
CA   (2) 9-cis-violaxanthin + O(2) = 2-cis,4-trans-xanthoxin + (3S,5R,6S)-5,6-
CA   epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al.
CA   (3) 9'-cis-neoxanthin + O(2) = 2-cis,4-trans-xanthoxin + (3S,5R,6R)-5,6-
CA   dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al.
CF   Iron.
CC   -!- Acts on 9-cis-violaxanthin and 9'-cis-neoxanthin but not on the all-
CC       trans isomers.
CC   -!- In vitro, it will cleave 9-cis-zeaxanthin.
CC   -!- Catalyzes the first step of abscisic-acid biosynthesis from
CC       carotenoids in chloroplasts, in response to water stress.
CC   -!- The other enzymes involved in the abscisic-acid biosynthesis pathway
CC       are EC 1.1.1.288, EC 1.2.3.14 and EC 1.14.13.93.
DR   O24592, NCED1_MAIZE;  Q9M6E8, NCED1_PHAVU;  O49505, NCED2_ARATH;
DR   Q9LRR7, NCED3_ARATH;  Q9C6Z1, NCED5_ARATH;  Q9LRM7, NCED6_ARATH;
DR   Q9M9F5, NCED9_ARATH;
//
ID   1.13.11.52
DE   Indoleamine 2,3-dioxygenase.
AN   IDO.
AN   Tryptophan pyrrolase.
CA   (1) D-tryptophan + O(2) = N-formyl-D-kynurenine.
CA   (2) L-tryptophan + O(2) = N-formyl-L-kynurenine.
CF   Heme.
CC   -!- Requires ascorbic acid and methylene blue for activity.
CC   -!- Has broader substrate specificity than EC 1.13.11.11.
CC   -!- Is induced in response to pathological conditions and host-defense
CC       mechanisms.
CC   -!- While the enzyme is more active with D-tryptophan than L-tryptophan,
CC       its only known function to date is in the metabolism of L-tryptophan.
CC   -!- Superoxide radicals can replace O(2) as oxygen donor.
PR   PROSITE; PDOC00684;
DR   P14902, I23O1_HUMAN;  P28776, I23O1_MOUSE;  Q9ERD9, I23O1_RAT  ;
//
ID   1.13.11.53
DE   Acireductone dioxygenase (Ni(2+)-requiring).
AN   2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase.
AN   Acireductone dioxygenase.
AN   ARD.
AN   E-2.
CA   1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) =
CA   3-(methylthio)propanoate + formate + CO.
CF   Nickel.
CC   -!- If Fe(2+) is bound instead of Ni(2+), the reaction catalyzed by
CC       EC 1.13.11.54 occurs instead.
CC   -!- The enzyme from Klebsiella oxytoca (formerly Klebsiella pneumoniae)
CC       ATCC 8724 is involved in the methionine salvage pathway.
DR   Q6D2V8, MTND1_ERWCT;  Q5YZV0, MTND1_NOCFA;  Q6D1G3, MTND2_ERWCT;
DR   Q5YQZ5, MTND2_NOCFA;  A5FUG5, MTND_ACICJ ;  Q0VPK4, MTND_ALCBS ;
DR   Q3M546, MTND_ANAVT ;  O67785, MTND_AQUAE ;  A7Z3X7, MTND_BACA2 ;
DR   A0RI45, MTND_BACAH ;  Q81MI9, MTND_BACAN ;  Q731Q9, MTND_BACC1 ;
DR   A7GS63, MTND_BACCN ;  Q819E5, MTND_BACCR ;  Q635P0, MTND_BACCZ ;
DR   Q6HEC6, MTND_BACHK ;  Q65KJ6, MTND_BACLD ;  A8FCH1, MTND_BACP2 ;
DR   O31669, MTND_BACSU ;  A9VFE2, MTND_BACWK ;  Q3ZBL1, MTND_BOVIN ;
DR   A5EES7, MTND_BRASB ;  Q5ZL43, MTND_CHICK ;  A8ANI2, MTND_CITK8 ;
DR   Q6PBX5, MTND_DANRE ;  A9BVZ7, MTND_DELAS ;  Q54ER6, MTND_DICDI ;
DR   Q6AWN0, MTND_DROME ;  A4W7Z2, MTND_ENT38 ;  A7MK12, MTND_ENTS8 ;
DR   Q3ZV00, MTND_ENTSA ;  B2VIR1, MTND_ERWT9 ;  B1YIX9, MTND_EXIS2 ;
DR   Q0RQV5, MTND_FRAAA ;  Q5L1D9, MTND_GEOKA ;  A4ILL8, MTND_GEOTN ;
DR   A9H8G4, MTND_GLUDA ;  Q5FRJ2, MTND_GLUOX ;  Q0BPT8, MTND_GRABC ;
DR   Q2SKZ1, MTND_HAHCH ;  Q9BV57, MTND_HUMAN ;  B4U606, MTND_HYDS0 ;
DR   Q9ZFE7, MTND_KLEOX ;  A6T672, MTND_KLEP7 ;  B0SFU6, MTND_LEPBA ;
DR   Q04NC2, MTND_LEPBJ ;  Q04WK1, MTND_LEPBL ;  B0SP94, MTND_LEPBP ;
DR   Q75FG2, MTND_LEPIC ;  Q8EXC0, MTND_LEPIN ;  A1TZ35, MTND_MARAV ;
DR   Q60AP8, MTND_METCA ;  A8YMJ4, MTND_MICAE ;  B0JUK9, MTND_MICAN ;
DR   Q99JT9, MTND_MOUSE ;  Q8YTJ3, MTND_NOSS1 ;  A7HU87, MTND_PARL1 ;
DR   A2CBN5, MTND_PROM3 ;  Q7V8X5, MTND_PROMM ;  Q48KM7, MTND_PSE14 ;
DR   A6V7A7, MTND_PSEA7 ;  Q02KH4, MTND_PSEAB ;  Q9I341, MTND_PSEAE ;
DR   Q4K8J5, MTND_PSEF5 ;  Q3KFI8, MTND_PSEPF ;  Q884P2, MTND_PSESM ;
DR   Q4ZVB9, MTND_PSEU2 ;  A4VM82, MTND_PSEU5 ;  Q562C9, MTND_RAT   ;
DR   Q6N7A6, MTND_RHOPA ;  B3QG72, MTND_RHOPT ;  A4FFQ4, MTND_SACEN ;
DR   O94286, MTND_SCHPO ;  A8GAB0, MTND_SERP5 ;  Q2NWC7, MTND_SODGM ;
DR   A9FCY0, MTND_SORC5 ;  Q828K8, MTND_STRAW ;  B4STR1, MTND_STRM5 ;
DR   B2FPP3, MTND_STRMK ;  B2VAA3, MTND_SULSY ;  Q31QM9, MTND_SYNE7 ;
DR   B1XPT2, MTND_SYNP2 ;  Q5N3L4, MTND_SYNP6 ;  A5GJ71, MTND_SYNPW ;
DR   Q7U8G6, MTND_SYNPX ;  A5GR53, MTND_SYNR3 ;  Q0ICL5, MTND_SYNS3 ;
DR   Q3AZ58, MTND_SYNS9 ;  Q3AI20, MTND_SYNSC ;  Q111G3, MTND_TRIEI ;
DR   Q8PLG1, MTND_XANAC ;  Q3BUE7, MTND_XANC5 ;  Q4UU50, MTND_XANC8 ;
DR   B0RSM4, MTND_XANCB ;  Q8P9N4, MTND_XANCP ;  Q2P3W5, MTND_XANOM ;
DR   B2SM83, MTND_XANOP ;  Q5H0X9, MTND_XANOR ;  Q3B8C8, MTND_XENLA ;
DR   Q6DIY2, MTND_XENTR ;  B2I5X3, MTND_XYLF2 ;  Q9PBD4, MTND_XYLFA ;
DR   B0U3A5, MTND_XYLFM ;  Q87C37, MTND_XYLFT ;  Q03677, MTND_YEAST ;
DR   A1JP10, MTND_YERE8 ;  A7FLL2, MTND_YERP3 ;  B2K632, MTND_YERPB ;
DR   A9R2Z6, MTND_YERPG ;  A4TPN0, MTND_YERPP ;  Q66E17, MTND_YERPS ;
DR   B1JIK4, MTND_YERPY ;
//
ID   1.13.11.54
DE   Acireductone dioxygenase (Fe(2+)-requiring).
AN   2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase.
AN   Acireductone dioxygenase.
AN   ARD'.
AN   E-2'.
CA   1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 4-(methylthio)-2-
CA   oxobutanoate + formate.
CF   Fe(2+).
CC   -!- If Ni(2+) is bound instead of Fe(2+), the reaction catalyzed by
CC       EC 1.13.11.53 occurs instead.
CC   -!- The enzyme from Klebsiella oxytoca (formerly Klebsiella pneumoniae)
CC       ATCC 8724 is involved in the methionine salvage pathway.
DR   Q6D2V8, MTND1_ERWCT;  Q5YZV0, MTND1_NOCFA;  Q6D1G3, MTND2_ERWCT;
DR   Q5YQZ5, MTND2_NOCFA;  A5FUG5, MTND_ACICJ ;  Q0VPK4, MTND_ALCBS ;
DR   Q3M546, MTND_ANAVT ;  O67785, MTND_AQUAE ;  A7Z3X7, MTND_BACA2 ;
DR   A0RI45, MTND_BACAH ;  Q81MI9, MTND_BACAN ;  Q731Q9, MTND_BACC1 ;
DR   A7GS63, MTND_BACCN ;  Q819E5, MTND_BACCR ;  Q635P0, MTND_BACCZ ;
DR   Q6HEC6, MTND_BACHK ;  Q65KJ6, MTND_BACLD ;  A8FCH1, MTND_BACP2 ;
DR   O31669, MTND_BACSU ;  A9VFE2, MTND_BACWK ;  A5EES7, MTND_BRASB ;
DR   A8ANI2, MTND_CITK8 ;  A9BVZ7, MTND_DELAS ;  A4W7Z2, MTND_ENT38 ;
DR   A7MK12, MTND_ENTS8 ;  Q3ZV00, MTND_ENTSA ;  B2VIR1, MTND_ERWT9 ;
DR   B1YIX9, MTND_EXIS2 ;  Q0RQV5, MTND_FRAAA ;  Q5L1D9, MTND_GEOKA ;
DR   A4ILL8, MTND_GEOTN ;  A9H8G4, MTND_GLUDA ;  Q5FRJ2, MTND_GLUOX ;
DR   Q0BPT8, MTND_GRABC ;  Q2SKZ1, MTND_HAHCH ;  B4U606, MTND_HYDS0 ;
DR   Q9ZFE7, MTND_KLEOX ;  A6T672, MTND_KLEP7 ;  B0SFU6, MTND_LEPBA ;
DR   Q04NC2, MTND_LEPBJ ;  Q04WK1, MTND_LEPBL ;  B0SP94, MTND_LEPBP ;
DR   Q75FG2, MTND_LEPIC ;  Q8EXC0, MTND_LEPIN ;  A1TZ35, MTND_MARAV ;
DR   Q60AP8, MTND_METCA ;  A8YMJ4, MTND_MICAE ;  B0JUK9, MTND_MICAN ;
DR   Q8YTJ3, MTND_NOSS1 ;  A7HU87, MTND_PARL1 ;  A2CBN5, MTND_PROM3 ;
DR   Q7V8X5, MTND_PROMM ;  Q48KM7, MTND_PSE14 ;  A6V7A7, MTND_PSEA7 ;
DR   Q02KH4, MTND_PSEAB ;  Q9I341, MTND_PSEAE ;  Q4K8J5, MTND_PSEF5 ;
DR   Q3KFI8, MTND_PSEPF ;  Q884P2, MTND_PSESM ;  Q4ZVB9, MTND_PSEU2 ;
DR   A4VM82, MTND_PSEU5 ;  Q6N7A6, MTND_RHOPA ;  B3QG72, MTND_RHOPT ;
DR   A4FFQ4, MTND_SACEN ;  A8GAB0, MTND_SERP5 ;  Q2NWC7, MTND_SODGM ;
DR   A9FCY0, MTND_SORC5 ;  Q828K8, MTND_STRAW ;  B4STR1, MTND_STRM5 ;
DR   B2FPP3, MTND_STRMK ;  B2VAA3, MTND_SULSY ;  Q31QM9, MTND_SYNE7 ;
DR   B1XPT2, MTND_SYNP2 ;  Q5N3L4, MTND_SYNP6 ;  A5GJ71, MTND_SYNPW ;
DR   Q7U8G6, MTND_SYNPX ;  A5GR53, MTND_SYNR3 ;  Q0ICL5, MTND_SYNS3 ;
DR   Q3AZ58, MTND_SYNS9 ;  Q3AI20, MTND_SYNSC ;  Q111G3, MTND_TRIEI ;
DR   Q8PLG1, MTND_XANAC ;  Q3BUE7, MTND_XANC5 ;  Q4UU50, MTND_XANC8 ;
DR   B0RSM4, MTND_XANCB ;  Q8P9N4, MTND_XANCP ;  Q2P3W5, MTND_XANOM ;
DR   B2SM83, MTND_XANOP ;  Q5H0X9, MTND_XANOR ;  B2I5X3, MTND_XYLF2 ;
DR   Q9PBD4, MTND_XYLFA ;  B0U3A5, MTND_XYLFM ;  Q87C37, MTND_XYLFT ;
DR   A1JP10, MTND_YERE8 ;  A7FLL2, MTND_YERP3 ;  B2K632, MTND_YERPB ;
DR   A9R2Z6, MTND_YERPG ;  A4TPN0, MTND_YERPP ;  Q66E17, MTND_YERPS ;
DR   B1JIK4, MTND_YERPY ;
//
ID   1.13.11.55
DE   Sulfur oxygenase/reductase.
AN   Sulfur oxygenase.
AN   Sulfur oxygenase reductase.
CA   4 sulfur + 4 H(2)O + O(2) = 2 H(2)S + 2 HSO(3)(-) + 2 H(+).
CF   Iron.
CC   -!- Elemental sulfur is both the electron donor and one of the two known
CC       acceptors, the other being oxygen.
CC   -!- Another reaction product is thiosulfate, but this is probably formed
CC       non-enzymically at elevated temperature from sulfite and sulfur.
CC   -!- This enzyme differs from EC 1.13.11.18 and EC 1.97.1.3 in that both
CC       activities are found together.
DR   P29082, SOR_ACIAM  ;
//
ID   1.13.11.56
DE   1,2-dihydroxynaphthalene dioxygenase.
AN   1,2-DHN dioxygenase.
AN   1,2-dihydroxynaphthalene oxygenase.
AN   DHNDO.
CA   Naphthalene-1,2-diol + O(2) = 2-hydroxy-2H-chromene-2-carboxylate.
CF   Iron.
CC   -!- This enzyme is involved in naphthalene degradation.
PR   PROSITE; PDOC00078;
//
ID   1.13.11.57
DE   Gallate dioxygenase.
CA   Gallate + O(2) = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate.
CF   Iron.
CC   -!- The enzyme is a ring-cleavage dioxygenase that acts specifically on
CC       gallate to produce the keto-tautomer of 4-oxalomesaconate.
//
ID   1.13.11.58
DE   Linoleate 9S-lipoxygenase.
AN   9-lipoxygenase.
AN   9S-lipoxygenase.
AN   Linoleate 9-lipoxygenase.
CA   Linoleate + O(2) = (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate.
CF   Iron.
CC   -!- A common plant lipoxygenase that oxidizes linoleate and alpha-
CC       linolenate, the two most common polyunsaturated fatty acids in
CC       plants, by inserting molecular oxygen at the C(9) position with (S)-
CC       configuration.
CC   -!- The enzyme plays a physiological role during the early stages of
CC       seedling growth.
CC   -!- The enzyme from Arabidopsis thaliana shows comparable activity toward
CC       linoleate and linolenate.
CC   -!- EC 1.13.11.12 catalyzes a similar reaction at another position of
CC       these fatty acids.
DR   P37831, LOX11_SOLTU;  O24379, LOX12_SOLTU;  Q43189, LOX13_SOLTU;
DR   Q43190, LOX14_SOLTU;  Q43191, LOX15_SOLTU;  Q41238, LOX16_SOLTU;
DR   O22507, LOX17_SOLTU;  O22508, LOX18_SOLTU;  Q06327, LOX1_ARATH ;
DR   P29114, LOX1_HORVU ;  P38414, LOX1_LENCU ;  Q76I22, LOX1_ORYSJ ;
DR   P08170, LOX1_SOYBN ;  P29250, LOX2_ORYSJ ;  P14856, LOX2_PEA   ;
DR   P09439, LOX2_SOYBN ;  Q7G794, LOX3_ORYSJ ;  P09918, LOX3_PEA   ;
DR   P09186, LOX3_SOYBN ;  Q53RB0, LOX4_ORYSJ ;  P38417, LOX4_SOYBN ;
DR   Q9LUW0, LOX5_ARATH ;  P27480, LOXA_PHAVU ;  P38415, LOXA_SOLLC ;
DR   P27481, LOXB_PHAVU ;  P38416, LOXB_SOLLC ;  P24095, LOXX_SOYBN ;
//
ID   1.13.11.n1
DE   2-aminophenol 1,6-dioxygenase.
CA   2-aminophenol + O(2) = 2-aminomuconate 6-semialdehyde.
CF   Iron.
DR   O33477, AMNB_PSESP ;
//
ID   1.13.12.1
DE   Arginine 2-monooxygenase.
AN   Arginine decarboxy-oxidase.
AN   Arginine decarboxylase.
AN   Arginine oxygenase (decarboxylating).
CA   L-arginine + O(2) = 4-guanidinobutanamide + CO(2) + H(2)O.
CF   Flavoprotein.
CC   -!- Also acts on canavanine and homoarginine.
//
ID   1.13.12.2
DE   Lysine 2-monooxygenase.
AN   Lysine oxygenase.
CA   L-lysine + O(2) = 5-aminopentanamide + CO(2) + H(2)O.
CF   FAD.
CC   -!- Also acts on other diamino acids.
//
ID   1.13.12.3
DE   Tryptophan 2-monooxygenase.
CA   L-tryptophan + O(2) = (indol-3-yl)acetamide + CO(2) + H(2)O.
DR   P25017, TR2M2_AGRVI;  Q09109, TR2M_AGRRH ;  P0A3V2, TR2M_AGRT4 ;
DR   Q04564, TR2M_AGRVS ;  Q47861, TR2M_PANAY ;  P06617, TR2M_PSESS ;
DR   P0A3V3, TR2M_RHIRD ;
//
ID   1.13.12.4
DE   Lactate 2-monooxygenase.
AN   Lactate oxidase.
AN   Lactate oxidative decarboxylase.
AN   Lactate oxygenase.
CA   (S)-lactate + O(2) = acetate + CO(2) + H(2)O.
CF   FMN.
CC   -!- Formerly EC 1.1.3.2.
PR   PROSITE; PDOC00482;
DR   P21795, LA2M_MYCSM ;  Q9HDX2, YKN3_SCHPO ;
//
ID   1.13.12.5
DE   Renilla-luciferin 2-monooxygenase.
AN   Aequorin.
AN   Luciferase.
AN   Renilla-type luciferase.
CA   Renilla luciferin + O(2) = oxidized Renilla luciferin + CO(2) + light.
CC   -!- From the soft coral coelenterate Renilla reniformis.
CC   -!- The luciferin is bound to a luciferin-binding protein (BP-LH2).
CC   -!- The bioluminescent reaction between the luciferin complex, luciferase
CC       and oxygen is triggered by calcium ions.
CC   -!- In vivo, the excited state luciferin--luciferase complex undergoes
CC       the process of nonradiative energy transfer to an accessory protein,
CC       Renilla green fluorescent protein, which results in green
CC       bioluminescence.
CC   -!- In vitro, Renilla luciferase emits blue light in the absence of any
CC       green fluorescent protein.
DR   P27652, LUCI_RENRE ;
//
ID   1.13.12.6
DE   Cypridina-luciferin 2-monooxygenase.
AN   Cypridina-type luciferase.
AN   Luciferase.
CA   Cypridina luciferin + O(2) = oxidized Cypridina luciferin + CO(2) +
CA   light.
CC   -!- Cypridina luciferin is a bioluminescent crustacea.
CC   -!- The enzyme may be assayed by measurement of light emission.
DR   P17554, LUCI_VARHI ;
//
ID   1.13.12.7
DE   Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing).
AN   Firefly luciferase.
AN   Luciferase.
AN   Photinus pyralis luciferase.
CA   Photinus luciferin + O(2) + ATP = oxidized Photinus luciferin + CO(2) +
CA   AMP + diphosphate + light.
CC   -!- Photinus (firefly) is a bioluminescent insect.
CC   -!- The first step in the reaction is the formation of an acid anhydride
CC       between the carboxylic group and AMP, with the release of
CC       diphosphate.
CC   -!- The enzyme may be assayed by measurement of light emission.
PR   PROSITE; PDOC00427;
DR   P13129, LUCI_LUCCR ;  Q01158, LUCI_LUCLA ;  Q26304, LUCI_LUCMI ;
DR   Q27757, LUCI_PHOPE ;  P08659, LUCI_PHOPY ;
//
ID   1.13.12.8
DE   Watasenia-luciferin 2-monooxygenase.
AN   Luciferase.
AN   Watasenia-type luciferase.
CA   Watasenia luciferin + O(2) = oxidized Watasenia luciferin + CO(2) +
CA   light.
CC   -!- The enzyme may be assayed by measurement of light emission.
//
ID   1.13.12.9
DE   Phenylalanine 2-monooxygenase.
AN   L-phenylalanine oxidase (deaminating and decarboxylating).
AN   Phenylalanine (deaminating, decarboxylating) oxidase.
CA   L-phenylalanine + O(2) = 2-phenylacetamide + CO(2) + H(2)O.
CC   -!- The reaction shown above is about 80% of the reaction catalyzed; the
CC       remaining 20% is: L-phenylalanine + O(2) + H(2)O = 3-phenylpyruvic
CC       acid + NH(3) + H(2)O(2), a reaction similar to that of EC 1.4.3.2.
//
ID   1.13.12.10
DE   Deleted entry.
//
ID   1.13.12.11
DE   Transferred entry: 1.14.13.8.
//
ID   1.13.12.12
DE   Apo-beta-carotenoid-14',13'-dioxygenase.
CA   8'-apo-beta-carotenol + O(2) = 14'-apo-beta-carotenal + 7-hydroxy-6-
CA   methylhepta-3,5-dienal.
CC   -!- A thiol-dependent enzyme.
CC   -!- Unlike EC 1.14.99.36, it is not active toward beta-carotene.
CC   -!- Presumably 2-methyl-6-oxohepta-2,4-dienal is also formed in this
CC       reaction.
//
ID   1.13.12.13
DE   Oplophorus-luciferin 2-monooxygenase.
AN   Oplophorus luciferase.
CA   Oplophorus luciferin + O(2) = oxidized Oplophorus luciferin + CO(2) +
CA   light.
CC   -!- The luciferase from the deep sea shrimp Oplophorus gracilorostris is
CC       a complex composed of more than one protein.
CC   -!- The enzyme's specificity is quite broad, with both coelenterazine and
CC       bisdeoxycoelenterazine being good substrates.
//
ID   1.13.12.14
DE   Transferred entry: 1.14.13.122.
//
ID   1.13.12.15
DE   3,4-dihydroxyphenylalanine oxidative deaminase.
AN   DOPA oxidative deaminase.
AN   DOPAODA.
AN   Oxidative deaminase.
CA   2 3,4-dihydroxy-L-phenylalanine + O(2) = 2 3,4-dihydroxyphenylpyruvate +
CA   2 NH(3).
CC   -!- One of the three enzymes involved in DOPA (3,4-
CC       dihydroxyphenylalanine) catabolism in the non-oxygenic phototrophic
CC       bacterium Rubrivivax benzoatilyticus OU5 (and not Rhodobacter
CC       sphaeroides OU5 as had been thought), the other two being EC 4.3.1.22
CC       and EC 2.6.1.49.
CC   -!- In addition to DOPA, the enzyme can also use L-tyrosine,
CC       L-phenylalanine, L-tryptophan and glutamate as substrate, but more
CC       slowly.
CC   -!- Inhibited by NADH and 2-oxoglutarate.
//
ID   1.13.12.16
DE   Nitronate monooxygenase.
AN   2-nitropropane dioxygenase.
AN   2-NPD.
AN   Nitroalkane oxidase.
AN   NMO.
CA   Ethylnitronate + O(2) = acetaldehyde + nitrite + other products.
CF   FMN.
CC   -!- Previously classified as EC 1.13.11.32, but it is now recognized that
CC       this was the result of the slow ionization of nitroalkanes to their
CC       nitronate (anionic) forms.
CC   -!- The enzymes from the fungus Neurospora crassa and the yeast
CC       Williopsis saturnus var. mrakii (formerly classified as Hansenula
CC       mrakii) contain non-covalently bound FMN as the cofactor.
CC   -!- Neither hydrogen peroxide nor superoxide were detected during enzyme
CC       turnover.
CC   -!- Active toward linear alkyl nitronates of lengths between 2 and 6
CC       carbon atoms and, with lower activity, toward propyl-2-nitronate.
CC   -!- The enzyme from N.crassa can also utilize neutral nitroalkanes,
CC       but with lower activity.
CC   -!- Formerly EC 1.13.11.32.
DR   P47177, 2NDP_YEAST ;  O05413, 2NPD_BACSU ;  Q12723, 2NPD_CYBMR ;
DR   Q01284, 2NPD_NEUCR ;  Q9I4V0, 2NPD_PSEAE ;  A6U025, 2NPD_STAA2 ;
DR   Q2FIF3, 2NPD_STAA3 ;  Q2FZX9, 2NPD_STAA8 ;  A5IR97, 2NPD_STAA9 ;
DR   Q5HHG4, 2NPD_STAAC ;  A6QFD2, 2NPD_STAAE ;  Q99VF6, 2NPD_STAAN ;
DR   Q6GIG7, 2NPD_STAAR ;  Q6GB05, 2NPD_STAAS ;  A8Z1H7, 2NPD_STAAT ;
DR   Q8NXG7, 2NPD_STAAW ;  Q4L4T4, 2NPD_STAHJ ;  Q49W60, 2NPD_STAS1 ;
//
ID   1.13.12.17
DE   Dichloroarcyriaflavin A synthase.
CA   Dichlorochromopyrrolate + 4 O(2) + 4 NADH = dichloroarcyriaflavin A +
CA   2 CO(2) + 6 H(2)O + 4 NAD(+).
CC   -!- The conversion of dichlorochromopyrrolate to dichloroarcyriaflavin A
CC       is a complex process that involves two enzyme components.
CC   -!- RebP is an NAD-dependent cytochrome P(450) oxygenase that performs an
CC       aryl-aryl bond formation yielding the six-ring indolocarbazole
CC       scaffold.
CC   -!- Along with RebC, a flavin-dependent hydroxylase, it also catalyzes
CC       the oxidative decarboxylation of both carboxyl groups.
CC   -!- The presence of RebC ensures that the only product is the
CC       rebeccamycin aglycone dichloroarcyriaflavin A.
CC   -!- The enzymes are similar, but not identical, to StaP and StaC, which
CC       are involved in the synthesis of staurosporine.
PR   PROSITE; PDOC00081;
//
ID   1.13.12.18
DE   Dinoflagellate luciferase.
CA   Dinoflagellate luciferin + O(2) = oxidized dinoflagellate luciferin +
CA   H(2)O + light.
CC   -!- A luciferase from dinoflagelates such as Gonyaulax polyhedra,
CC       Lingulodinium polyedrum, Noctiluca scintillans, and Pyrocystis
CC       lunula.
CC   -!- It is a single protein with three luciferase domains.
CC   -!- The luciferin is strongly bound by a luciferin binding protein above
CC       a pH of 7.
//
ID   1.13.99.1
DE   Inositol oxygenase.
AN   Meso-inositol oxygenase.
AN   MOO.
AN   Myo-inositol oxygenase.
CA   Myo-inositol + O(2) = D-glucuronate + H(2)O.
CF   Iron.
CC   -!- Formerly EC 1.13.1.11 and EC 1.99.2.6.
DR   Q8L799, MIOX1_ARATH;  O82200, MIOX2_ARATH;  Q8H1S0, MIOX4_ARATH;
DR   Q9FJU4, MIOX5_ARATH;  A7MBE4, MIOX_BOVIN ;  Q4V8T0, MIOX_DANRE ;
DR   Q54GH4, MIOX_DICDI ;  Q9UGB7, MIOX_HUMAN ;  Q9QXN5, MIOX_MOUSE ;
DR   Q5Z8T3, MIOX_ORYSJ ;  Q8WN98, MIOX_PIG   ;  Q5REY9, MIOX_PONAB ;
DR   Q9QXN4, MIOX_RAT   ;
//
ID   1.13.99.2
DE   Transferred entry: 1.14.12.10.
//
ID   1.13.99.3
DE   Tryptophan 2'-dioxygenase.
AN   Indole-3-alkane alpha-hydroxylase.
AN   Tryptophan side-chain alpha,beta-oxidase.
AN   Tryptophan side-chain oxidase.
AN   TSO.
CA   L-tryptophan + O(2) = (indol-3-yl)glycolaldehyde + CO(2) + NH(3).
CF   Heme.
CC   -!- Acts on a number of indole-3-alkane derivatives, oxidizing the
CC       3-side-chain in the 2'-position.
CC   -!- Best substrates are L-tryptophan and 5-hydroxy-L-tryptophan.
//
ID   1.13.99.4
DE   Transferred entry: 1.14.12.9.
//
ID   1.13.99.5
DE   Transferred entry: 1.13.11.47.
//
ID   1.14.1.1
DE   Transferred entry: 1.14.14.1.
//
ID   1.14.1.2
DE   Transferred entry: 1.14.13.9.
//
ID   1.14.1.3
DE   Transferred entry: 1.14.99.7 and 5.4.99.7.
//
ID   1.14.1.4
DE   Transferred entry: 1.14.99.2.
//
ID   1.14.1.5
DE   Transferred entry: 1.14.13.5.
//
ID   1.14.1.6
DE   Transferred entry: 1.14.15.4.
//
ID   1.14.1.7
DE   Transferred entry: 1.14.99.9.
//
ID   1.14.1.8
DE   Transferred entry: 1.14.99.10.
//
ID   1.14.1.9
DE   Deleted entry.
//
ID   1.14.1.10
DE   Transferred entry: 1.14.99.11.
//
ID   1.14.1.11
DE   Deleted entry.
//
ID   1.14.2.1
DE   Transferred entry: 1.14.17.1.
//
ID   1.14.2.2
DE   Transferred entry: 1.13.11.27.
//
ID   1.14.3.1
DE   Transferred entry: 1.14.16.1.
//
ID   1.14.11.1
DE   Gamma-butyrobetaine dioxygenase.
AN   Gamma-BBH.
AN   Gamma-butyrobetaine hydroxylase.
AN   Gamma-butyrobetaine,2-oxoglutarate dioxygenase.
CA   4-trimethylammoniobutanoate + 2-oxoglutarate + O(2) = 3-hydroxy-4-
CA   trimethylammoniobutanoate + succinate + CO(2).
CF   Iron; L-ascorbate.
DR   Q19000, BODG_CAEEL ;  O75936, BODG_HUMAN ;  Q924Y0, BODG_MOUSE ;
DR   Q5R5D8, BODG_PONAB ;  P80193, BODG_PSESK ;  Q9QZU7, BODG_RAT   ;
DR   Q98KK0, BODG_RHILO ;
//
ID   1.14.11.2
DE   Procollagen-proline dioxygenase.
AN   Procollagen-proline 4-dioxygenase.
AN   Procollagen-proline,2-oxoglutarate-4-dioxygenase.
AN   Proline hydroxylase.
AN   Proline,2-oxoglutarate 4-dioxygenase.
AN   Prolyl 4-hydroxylase.
AN   Prolyl hydroxylase.
AN   Protocollagen hydroxylase.
CA   L-proline-[procollagen] + 2-oxoglutarate + O(2) = trans-4-hydroxy-L-
CA   proline-[procollagen] + succinate + CO(2).
CF   Iron; L-ascorbate.
PR   PROSITE; PDOC00172;
PR   PROSITE; PDOC51471;
DR   Q1RMU3, P4HA1_BOVIN;  Q10576, P4HA1_CAEEL;  P16924, P4HA1_CHICK;
DR   P13674, P4HA1_HUMAN;  Q60715, P4HA1_MOUSE;  Q5RAG8, P4HA1_PONAB;
DR   P54001, P4HA1_RAT  ;  Q20065, P4HA2_CAEEL;  Q5ZLK5, P4HA2_CHICK;
DR   O15460, P4HA2_HUMAN;  Q60716, P4HA2_MOUSE;  Q75UG4, P4HA3_BOVIN;
DR   Q7Z4N8, P4HA3_HUMAN;  Q6W3F0, P4HA3_MOUSE;  Q6W3E9, P4HA3_RAT  ;
DR   Q5UP57, P4H_MIMIV  ;
//
ID   1.14.11.3
DE   Pyrimidine-deoxynucleoside 2'-dioxygenase.
AN   Deoxyuridine 2'-dioxygenase.
AN   Deoxyuridine 2'-hydroxylase.
AN   Pyrimidine deoxyribonucleoside 2'-hydroxylase.
AN   Pyrimidine-deoxynucleoside,2-oxoglutarate 2'-dioxygenase.
AN   Thymidine 2'-dioxygenase.
AN   Thymidine 2'-hydroxylase.
AN   Thymidine 2-oxoglutarate dioxygenase.
AN   Thymidine dioxygenase.
CA   2'-deoxyuridine + 2-oxoglutarate + O(2) = uridine + succinate + CO(2).
CF   Iron; L-ascorbate.
CC   -!- Also acts on thymidine (cf. EC 1.14.11.10).
//
ID   1.14.11.4
DE   Procollagen-lysine 5-dioxygenase.
AN   Lysine hydroxylase.
AN   Lysine,2-oxoglutarate 5-dioxygenase.
AN   Lysyl hydroxylase.
AN   Procollagen-lysine,2-oxoglutarate 5-dioxygenase.
CA   L-lysine-[procollagen] + 2-oxoglutarate + O(2) = (2S,5R)-5-hydroxy-L-
CA   lysine-[procollagen] + succinate + CO(2).
CF   Iron; L-ascorbate.
PR   PROSITE; PDOC01028;
PR   PROSITE; PDOC51471;
DR   O77588, PLOD1_BOVIN;  P24802, PLOD1_CHICK;  Q02809, PLOD1_HUMAN;
DR   Q9R0E2, PLOD1_MOUSE;  Q5R9N3, PLOD1_PONAB;  Q63321, PLOD1_RAT  ;
DR   O00469, PLOD2_HUMAN;  Q9R0B9, PLOD2_MOUSE;  Q811A3, PLOD2_RAT  ;
DR   O60568, PLOD3_HUMAN;  Q9R0E1, PLOD3_MOUSE;  Q5R6K5, PLOD3_PONAB;
DR   Q5U367, PLOD3_RAT  ;  Q20679, PLOD_CAEEL ;  Q5UQC3, PLOD_MIMIV ;
//
ID   1.14.11.5
DE   Transferred entry: 1.14.11.6.
//
ID   1.14.11.6
DE   Thymine dioxygenase.
AN   Thymine 7-hydroxylase.
AN   Thymine,2-oxoglutarate dioxygenase.
CA   Thymine + 2-oxoglutarate + O(2) = 5-hydroxymethyluracil + succinate +
CA   CO(2).
CF   Iron; L-ascorbate.
CC   -!- Also acts on 5-hydroxymethyluracil to oxidize its -CH(2)-OH group
CC       first to -CHO and then to -COOH.
CC   -!- Formerly EC 1.14.11.5.
DR   Q4DBW3, JBP1A_TRYCR;  Q4DLX9, JBP1B_TRYCR;  Q9U6M2, JBP1_CRIFA ;
DR   A4H5X5, JBP1_LEIBR ;  A4HU70, JBP1_LEIIN ;  Q4QHM7, JBP1_LEIMA ;
DR   Q9U6M1, JBP1_LEITA ;  P86938, JBP1_TRYB2 ;  P86937, JBP1_TRYBB ;
DR   A4H7G5, JBP2_LEIBR ;  A4HVU6, JBP2_LEIIN ;  Q4QFY1, JBP2_LEIMA ;
DR   B6EU02, JBP2_LEITA ;  Q57X81, JBP2_TRYBB ;  Q4DCH3, JBP2_TRYCR ;
//
ID   1.14.11.7
DE   Procollagen-proline 3-dioxygenase.
AN   Procollagen-proline,2-oxoglutarate 3-dioxygenase.
AN   Proline,2-oxoglutarate 3-dioxygenase.
AN   Prolyl 3-hydroxylase.
CA   L-proline-[procollagen] + 2-oxoglutarate + O(2) = trans-3-hydroxy-L-
CA   proline-[procollagen] + succinate + CO(2).
CF   Iron; L-ascorbate.
PR   PROSITE; PDOC51471;
DR   Q6JHU8, P3H1_CHICK ;  Q32P28, P3H1_HUMAN ;  Q3V1T4, P3H1_MOUSE ;
DR   Q9R1J8, P3H1_RAT   ;  Q6JHU7, P3H2_CHICK ;  Q8IVL5, P3H2_HUMAN ;
DR   Q8CG71, P3H2_MOUSE ;  Q4KLM6, P3H2_RAT   ;  Q8IVL6, P3H3_HUMAN ;
DR   Q8CG70, P3H3_MOUSE ;
//
ID   1.14.11.8
DE   Trimethyllysine dioxygenase.
AN   Epsilon-trimethyllysine 2-oxoglutarate dioxygenase.
AN   TML dioxygenase.
AN   TML hydroxylase.
AN   TML-alpha-ketoglutarate dioxygenase.
AN   TMLD.
AN   Trimethyllysine alpha-ketoglutarate dioxygenase.
AN   Trimethyllysine,2-oxoglutarate dioxygenase.
CA   N(6),N(6),N(6)-trimethyl-L-lysine + 2-oxoglutarate + O(2) = 3-hydroxy-
CA   N(6),N(6),N(6)-trimethyl-L-lysine + succinate + CO(2).
CF   Fe(2+); L-ascorbate.
DR   Q0VC74, TMLH_BOVIN ;  Q5F4B3, TMLH_CHICK ;  Q9NVH6, TMLH_HUMAN ;
DR   Q91ZE0, TMLH_MOUSE ;  Q96UB1, TMLH_NEUCR ;  A5DCB6, TMLH_PICGU ;
DR   Q91ZW6, TMLH_RAT   ;
//
ID   1.14.11.9
DE   Flavanone 3-dioxygenase.
AN   (2S)-flavanone 3-hydroxylase.
AN   Flavanone 3-beta-hydroxylase.
AN   Flavanone 3-hydroxylase.
AN   Flavanone synthase I.
AN   Naringenin 3-dioxygenase.
AN   Naringenin 3-hydroxylase.
AN   Naringenin,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating).
CA   A flavanone + 2-oxoglutarate + O(2) = a dihydroflavonol + succinate +
CA   CO(2).
CF   Iron; L-ascorbate.
PR   PROSITE; PDOC51471;
DR   Q9S818, FL3H_ARATH ;  Q05963, FL3H_CALCH ;  Q05964, FL3H_DIACA ;
DR   P28038, FL3H_HORVU ;  Q06942, FL3H_MALDO ;  Q05965, FL3H_MATIN ;
DR   Q7XZQ7, FL3H_PETCR ;  Q07353, FL3H_PETHY ;  P41090, FL3H_VITVI ;
DR   Q96330, FLS1_ARATH ;  Q9ZWQ9, FLS_CITUN  ;  Q9M547, FLS_EUSGR  ;
DR   Q9XHG2, FLS_MALDO  ;  O04395, FLS_MATIN  ;  Q7XZQ6, FLS_PETCR  ;
DR   Q07512, FLS_PETHY  ;  Q41452, FLS_SOLTU  ;
//
ID   1.14.11.10
DE   Pyrimidine-deoxynucleoside 1'-dioxygenase.
AN   Deoxyuridine-uridine 1'-dioxygenase.
AN   Pyrimidine-deoxynucleoside,2-oxoglutarate 1'-dioxygenase.
CA   2'-deoxyuridine + 2-oxoglutarate + O(2) = uracil + 2-deoxyribonolactone +
CA   succinate + CO(2).
CF   Iron; L-ascorbate.
CC   -!- Cf. EC 1.14.11.3.
//
ID   1.14.11.11
DE   Hyoscyamine (6S)-dioxygenase.
AN   Hyoscyamine (6S)-hydroxylase.
AN   Hyoscyamine 6-beta-hydroxylase.
CA   L-hyoscyamine + 2-oxoglutarate + O(2) = (6S)-hydroxyhyoscyamine +
CA   succinate + CO(2).
CF   Iron; L-ascorbate.
PR   PROSITE; PDOC51471;
DR   P24397, HY6H_HYONI ;
//
ID   1.14.11.12
DE   Gibberellin-44 dioxygenase.
AN   Gibberellin A44 oxidase.
CA   Gibberellin 44 + 2-oxoglutarate + O(2) = gibberellin 19 + succinate +
CA   CO(2).
CF   Iron.
//
ID   1.14.11.13
DE   Gibberellin 2-beta-dioxygenase.
AN   Gibberellin 2-beta-hydroxylase.
CA   Gibberellin 1 + 2-oxoglutarate + O(2) = 2-beta-hydroxygibberellin 1 +
CA   succinate + CO(2).
CF   Iron.
CC   -!- Also acts on a number of other gibberellins.
PR   PROSITE; PDOC51471;
DR   Q8LEA2, G2OX1_ARATH;  Q9SQ80, G2OX1_PEA  ;  Q9XFR9, G2OX2_ARATH;
DR   Q9XHM5, G2OX2_PEA  ;  O64692, G2OX3_ARATH;  Q9C6I4, G2OX7_ARATH;
DR   O49561, G2OX8_ARATH;  Q9XG83, G2OX_PHACN ;
//
ID   1.14.11.14
DE   6-beta-hydroxyhyoscyamine epoxidase.
AN   Hydroxyhyoscyamine dioxygenase.
CA   (6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O(2) = scopolamine +
CA   succinate + CO(2) + H(2)O.
CF   Iron; L-ascorbate.
//
ID   1.14.11.15
DE   Gibberellin 3-beta-dioxygenase.
AN   Gibberellin 3-beta-hydroxylase.
CA   Gibberellin 20 + 2-oxoglutarate + O(2) = gibberellin 1 + succinate +
CA   CO(2).
CF   Iron; L-ascorbate.
PR   PROSITE; PDOC51471;
DR   Q3I411, G3O21_WHEAT;  Q3I410, G3O22_WHEAT;  Q3I409, G3O23_WHEAT;
DR   Q39103, G3OX1_ARATH;  Q9ZT84, G3OX2_ARATH;  Q9SVS8, G3OX3_ARATH;
DR   Q9C971, G3OX4_ARATH;
//
ID   1.14.11.16
DE   Peptide-aspartate beta-dioxygenase.
AN   Aspartate beta-hydroxylase.
AN   Aspartyl/asparaginyl beta-hydroxylase.
CA   Peptide L-aspartate + 2-oxoglutarate + O(2) = peptide 3-hydroxy-L-
CA   aspartate + succinate + CO(2).
CF   Iron.
CC   -!- Some vitamin K-dependent coagulation factors, as well as synthetic
CC       peptides based on the structure of the first epidermal growth factor
CC       domain of human coagulation factor IX or X, can act as acceptors.
DR   Q28056, ASPH_BOVIN ;  Q12797, ASPH_HUMAN ;  Q8BSY0, ASPH_MOUSE ;
DR   P59723, HIF1N_DANRE;  Q9NWT6, HIF1N_HUMAN;  Q8BLR9, HIF1N_MOUSE;
//
ID   1.14.11.17
DE   Taurine dioxygenase.
AN   2-aminoethanesulfonate dioxygenase.
AN   Alpha-ketoglutarate-dependent taurine dioxygenase.
CA   Taurine + 2-oxoglutarate + O(2) = sulfite + aminoacetaldehyde + succinate
CA   + CO(2).
CF   Iron; L-ascorbate.
CC   -!- The enzyme from Escherichia coli also acts on pentanesulfonate,
CC       3-(N-morpholino)propanesulfonate and 2-(1,3-dioxoisoindolin-2-
CC       yl)ethanesulfonate, but at lower rates.
DR   P37610, TAUD_ECOLI ;
//
ID   1.14.11.18
DE   Phytanoyl-CoA dioxygenase.
AN   Phytanoyl-CoA 2 oxoglutarate dioxygenase.
AN   Phytanoyl-CoA 2-hydroxylase.
AN   Phytanoyl-CoA alpha-hydroxylase.
AN   Phytanoyl-CoA hydroxylase.
CA   Phytanoyl-CoA + 2-oxoglutarate + O(2) = 2-hydroxyphytanoyl-CoA +
CA   succinate + CO(2).
CF   Iron; L-ascorbate.
CC   -!- Part of the peroxisomal phytanic acid alpha-oxidation pathway.
DR   O18778, PAHX_BOVIN ;  O62515, PAHX_CAEEL ;  O14832, PAHX_HUMAN ;
DR   O35386, PAHX_MOUSE ;  P57093, PAHX_RAT   ;
//
ID   1.14.11.19
DE   Leucocyanidin oxygenase.
AN   Anthocyanidin synthase.
AN   Leucoanthocyanidin dioxygenase.
CA   Leucocyanidin + 2-oxoglutarate + O(2) = cis- and trans-dihydroquercetins
CA   + succinate + CO(2) + H(2)O.
CF   Iron; L-ascorbate.
CC   -!- Involved in the pathway by which many flowering plants make
CC       anthocyanin (glycosylated anthocyandin) flower pigments.
CC   -!- The intermediates are transformed into cis- and trans-
CC       dihydroquercetin, which the enzyme can also oxidize to quercetin.
CC   -!- Acidification of the products gives anthocyanidin, which, however,
CC       may not be a natural precursor of the anthocyanins.
PR   PROSITE; PDOC51471;
DR   Q96323, LDOX_ARATH ;  P41213, LDOX_MAIZE ;  P51091, LDOX_MALDO ;
DR   O04274, LDOX_PERFR ;  P51092, LDOX_PETHY ;  P51093, LDOX_VITVI ;
//
ID   1.14.11.20
DE   Deacetoxyvindoline 4-hydroxylase.
AN   D17H.
AN   Desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4-beta-
AN   hydroxylating).
AN   Desacetoxyvindoline-4-hydroxylase.
AN   Desacetyoxyvindoline-17-hydroxylase.
CA   Deacetoxyvindoline + 2-oxoglutarate + O(2) = deacetylvindoline +
CA   succinate + CO(2).
CF   Iron; L-ascorbate.
CC   -!- Also acts, to a lesser extent, on 16-methoxy-2,3-dihydrotabersonine.
PR   PROSITE; PDOC51471;
DR   O04847, DV4H_CATRO ;
//
ID   1.14.11.21
DE   Clavaminate synthase.
AN   Clavaminic acid synthase.
CA   (1) Deoxyamidinoproclavaminate + 2-oxoglutarate + O(2) =
CA   amidinoproclavaminate + succinate + CO(2).
CA   (2) Proclavaminate + 2-oxoglutarate + O(2) = dihydroclavaminate +
CA   succinate + CO(2) + H(2)O.
CA   (3) Dihydroclavaminate + 2-oxoglutarate + O(2) = clavaminate + succinate
CA   + CO(2) + H(2)O.
CF   Iron.
CC   -!- Catalyzes three separate oxidative reactions in the pathway for the
CC       biosythesis of the beta-lactamase inhibitor clavulanate in
CC       Streptomyces clavuligerus.
CC   -!- The first step (hydroxylation) is separated from the latter two
CC       (oxidative cyclization and desaturation) by the action of
CC       EC 3.5.3.22.
CC   -!- The three reactions are all catalyzed at the same nonheme iron site.
DR   Q05581, CAS1_STRCL ;  Q05582, CAS2_STRCL ;
//
ID   1.14.11.22
DE   Flavone synthase.
AN   Flavone synthase I.
AN   FNS I.
CA   A flavanone + 2-oxoglutarate + O(2) = a flavone + succinate + CO(2) +
CA   H(2)O.
CF   Iron; L-ascorbate.
PR   PROSITE; PDOC51471;
DR   Q7XZQ8, FNSI_PETCR ;
//
ID   1.14.11.23
DE   Flavonol synthase.
AN   Flavonoid 2-oxoglutarate-dependent dioxygenase.
AN   FLS.
CA   A dihydroflavonol + 2-oxoglutarate + O(2) = a flavonol + succinate +
CA   CO(2) + H(2)O.
CF   Iron.
CC   -!- In addition to the desaturation of (2R,3R)-dihydroflavonols to
CC       flavonols, the enzyme from the satsuma Citrus unshiu also has a non-
CC       specific activity that trans-hydroxylates the flavanones (2S)-
CC       naringenin and the unnatural (2R)-naringenin at C-3 to kaempferol and
CC       (2R,3R)-dihydrokaempferol, respectively.
PR   PROSITE; PDOC51471;
DR   Q96330, FLS1_ARATH ;  Q9ZWQ9, FLS_CITUN  ;  Q9M547, FLS_EUSGR  ;
DR   Q9XHG2, FLS_MALDO  ;  O04395, FLS_MATIN  ;  Q7XZQ6, FLS_PETCR  ;
DR   Q07512, FLS_PETHY  ;  Q41452, FLS_SOLTU  ;
//
ID   1.14.11.24
DE   2'-deoxymugineic-acid 2'-dioxygenase.
AN   IDS3.
CA   2'-deoxymugineic acid + 2-oxoglutarate + O(2) = mugineic acid + succinate
CA   + CO(2).
CF   Iron.
CC   -!- It is also likely that this enzyme can catalyze the hydroxylation of
CC       3-epihydroxy-2'-deoxymugineic acid to form 3-epihydroxymugineic acid.
PR   PROSITE; PDOC51471;
DR   Q40062, IDS3_HORVU ;
//
ID   1.14.11.25
DE   Mugineic-acid 3-dioxygenase.
AN   IDS2.
CA   (1) Mugineic acid + 2-oxoglutarate + O(2) = 3-epihydroxymugineic acid +
CA   succinate + CO(2).
CA   (2) 2'-deoxymugineic acid + 2-oxoglutarate + O(2) = 3-epihydroxy-
CA   2'-deoxymugineic acid + succinate + CO(2).
CF   Fe(2+).
PR   PROSITE; PDOC51471;
DR   Q40061, IDS2_HORVU ;
//
ID   1.14.11.26
DE   Deacetoxycephalosporin-C hydroxylase.
AN   3'-methylcephem hydroxylase.
AN   DACS.
AN   DAOC hydroxylase.
AN   Deacetoxycephalosporin C hydroxylase.
AN   Deacetylcephalosporin C synthase.
CA   Deacetoxycephalosporin C + 2-oxoglutarate + O(2) = deacetylcephalosporin
CA   C + succinate + CO(2).
CF   Iron.
CC   -!- The enzyme can also use 3-exomethylenecephalosporin C as a substrate
CC       to form deacetoxycephalosporin C, although more slowly.
CC   -!- In Acremonium chrysogenum, the enzyme forms part of a bifunctional
CC       protein along with EC 1.14.20.1.
CC   -!- It is a separate enzyme in Streptomyces clavuligerus.
PR   PROSITE; PDOC00165;
PR   PROSITE; PDOC51471;
DR   P42219, CEFF_NOCLA ;  P42220, CEFF_STRCL ;  P11935, EXPA_CEPAC ;
//
ID   1.14.11.27
DE   [Histone H3]-lysine-36 demethylase.
AN   H3-K36-specific demethylase.
AN   Histone demethylase.
AN   Histone-lysine (H3-K36) demethylase.
AN   JHDM1A.
AN   JmjC domain-containing histone demethylase 1A.
CA   (1) Protein N(6),N(6)-dimethyl-L-lysine + 2-oxoglutarate + O(2) = protein
CA   N(6)-methyl-L-lysine + succinate + formaldehyde + CO(2).
CA   (2) Protein N(6)-methyl-L-lysine + 2-oxoglutarate + O(2) = protein
CA   L-lysine + succinate + formaldehyde + CO(2).
CF   Fe(2+).
CC   -!- Of the seven potential methylation sites in histones H3 (K4, K9, K27,
CC       K36, K79) and H4 (K20, R3) from HeLa cells, the enzyme is specific
CC       for Lys-36.
CC   -!- Lysine residues exist in three methylation states (mono-, di- and
CC       trimethylated).
CC   -!- The enzyme preferentially demethylates the dimethyl form of Lys-36
CC       (K36me2), which is its natural substrate, to form the monomethyl and
CC       unmethylated forms of Lys-36.
CC   -!- It can also demethylate the monomethyl- but not the trimethyl form of
CC       Lys-36.
DR   Q75AL5, JHD1_ASHGO ;  Q4WHB7, JHD1_ASPFU ;  Q60V67, JHD1_CAEBR ;
DR   Q95Q98, JHD1_CAEEL ;  Q5A847, JHD1_CANAL ;  Q6FPL6, JHD1_CANGA ;
DR   P0CO41, JHD1_CRYNB ;  P0CO40, JHD1_CRYNJ ;  Q6BXJ4, JHD1_DEBHA ;
DR   Q9VHH9, JHD1_DROME ;  Q5AW75, JHD1_EMENI ;  Q6CIC9, JHD1_KLULA ;
DR   O94603, JHD1_SCHPO ;  Q4P5U1, JHD1_USTMA ;  Q6C423, JHD1_YARLI ;
DR   P40034, JHD1_YEAST ;  Q9Y2K7, KDM2A_HUMAN;  P59997, KDM2A_MOUSE;
DR   Q5U263, KDM2A_XENTR;  Q8NHM5, KDM2B_HUMAN;  Q6P1G2, KDM2B_MOUSE;
DR   Q640I9, KDM2B_XENLA;  Q1JP61, KDM8_BOVIN ;  A8E534, KDM8_DANRE ;
DR   Q8N371, KDM8_HUMAN ;  Q9CXT6, KDM8_MOUSE ;  Q497B8, KDM8_RAT   ;
DR   B5XF11, KDM8_SALSA ;  B2GUS6, KDM8_XENTR ;  Q16W06, NO66_AEDAE ;
DR   A5PK74, NO66_BOVIN ;  C3XRY1, NO66_BRAFL ;  A8QFQ3, NO66_BRUMA ;
DR   A8XEA2, NO66_CAEBR ;  O01658, NO66_CAEEL ;  Q5ZMM1, NO66_CHICK ;
DR   B0WMG3, NO66_CULQU ;  A3KP59, NO66_DANRE ;  Q54K96, NO66_DICDI ;
DR   B3MSI4, NO66_DROAN ;  B3NU20, NO66_DROER ;  B4JMQ2, NO66_DROGR ;
DR   Q7K4H4, NO66_DROME ;  B4L6Q5, NO66_DROMO ;  B4GUZ2, NO66_DROPE ;
DR   B5DUH6, NO66_DROPS ;  B4I100, NO66_DROSE ;  B4R4H1, NO66_DROSI ;
DR   B4M7P8, NO66_DROVI ;  B4NP88, NO66_DROWI ;  B4Q068, NO66_DROYA ;
DR   Q9H6W3, NO66_HUMAN ;  Q9JJF3, NO66_MOUSE ;  Q9UPP1, PHF8_HUMAN ;
DR   Q80TJ7, PHF8_MOUSE ;
//
ID   1.14.11.28
DE   Proline 3-hydroxylase.
AN   P-3-H.
CA   L-proline + 2-oxoglutarate + O(2) = cis-3-hydroxy-L-proline + succinate +
CA   CO(2).
CF   Fe(2+).
CC   -!- Unlike the proline hydroxylases involved in collagen biosynthesis
CC       (EC 1.14.11.2 and EC 1.14.11.7), this enzyme does not require
CC       ascorbate for activity although it does increase the activity of the
CC       enzyme.
CC   -!- The enzyme is specific for L-proline as D-proline, trans-4-hydroxy-L-
CC       proline, cis-4-hydroxy-L-proline and 3,4-dehydro-DL-proline are not
CC       substrates.
DR   P96010, P3H1_STRSQ ;  O09345, P3H2_STRSQ ;
//
ID   1.14.11.29
DE   Hypoxia-inducible factor-proline dioxygenase.
AN   HIF hydroxylase.
CA   Hypoxia-inducible factor-L-proline + 2-oxoglutarate + O(2) = hypoxia-
CA   inducible factor-trans-4-hydroxy-L-proline + succinate + CO(2).
CF   Iron; L-ascorbate.
CC   -!- Contains iron, and requires ascorbate.
CC   -!- Specifically hydroxylates a proline residue in HIF-alpha, the alpha
CC       subunit of the transcriptional regulator HIF (hypoxia-inducible
CC       factor), which targets HIF for proteasomal destruction.
CC   -!- The requirement of oxygen for the hydroxylation reaction enables
CC       animals to respond to hypoxia.
//
ID   1.14.11.30
DE   Hypoxia-inducible factor-asparagine dioxygenase.
AN   HIF hydroxylase.
CA   Hypoxia-inducible factor-L-asparagine + 2-oxoglutarate + O(2) = hypoxia-
CA   inducible factor-(3S)-3-hydroxy-L-asparagine + succinate + CO(2).
CF   Iron; L-ascorbate.
CC   -!- Contains iron, and requires ascorbate.
CC   -!- Catalyzes hydroxylation of an asparagine in the C-terminal
CC       transcriptional activation domain of HIF-alpha, the alpha subunit of
CC       the transcriptional regulator HIF (hypoxia-inducible factor), which
CC       reduces its interaction with the transcriptional coactivator protein
CC       p300.
CC   -!- The requirement of oxygen for the hydroxylation reaction enables
CC       animals to respond to hypoxia.
//
ID   1.14.11.31
DE   Thebaine 6-O-demethylase.
CA   Thebaine + 2-oxoglutarate + O(2) = neopinone + formaldehyde + succinate +
CA   CO(2).
CF   Iron.
CC   -!- Requires Fe(2+).
CC   -!- Catalyzes a step in morphine biosynthesis.
CC   -!- The product neopinione spontaneously rearranges to the more stable
CC       codeinone.
CC   -!- The enzyme also catalyzes the 6-O-demethylation of oripavine to
CC       morphinone, with lower efficiency.
DR   D4N500, DIOX1_PAPSO;
//
ID   1.14.11.32
DE   Codeine 3-O-demethylase.
AN   Codeine O-demethylase.
CA   Codeine + 2-oxoglutarate + O(2) = morphine + formaldehyde + succinate +
CA   CO(2).
CF   Iron.
CC   -!- Requires Fe(2+).
CC   -!- Catalyzes a step in morphine biosynthesis.
CC   -!- The enzyme also catalyzes the 3-O-demethylation of thebaine to
CC       oripavine, with lower efficiency.
DR   D4N502, DIOX3_PAPSO;
//
ID   1.14.11.33
DE   DNA oxidative demethylase.
AN   Alkylated DNA repair protein.
CA   DNA-base-CH(3) + 2-oxoglutarate + O(2) = DNA-base + formaldehyde +
CA   succinate + CO(2).
CF   Iron.
CC   -!- Activity is slightly stimulated by ascorbate.
CC   -!- Catalyzes oxidative demethylation of the DNA base lesions N(1)-
CC       methyladenine, N(3)-methylcytosine, N(1)-methylguanine, and N(3)-
CC       methylthymine.
CC   -!- It works better on single-stranded DNA (ssDNA) and is capable of
CC       repairing damaged bases in RNA.
//
ID   1.14.11.n1
DE   L-asparagine oxygenase.
AN   L-asparagine 3-hydroxylase.
CA   L-asparagine + 2-oxoglutarate + O(2) = (2S,3S)-3-hydroxyasparagine +
CA   succinate + CO(2).
CF   Iron.
CC   -!- Catalyzes the direct beta-hydroxylation of L-asparagine to (2S,3S)-3-
CC       hydroxyasparagine.
CC   -!- The beta-hydroxylated asparagine produced is incorporated at position
CC       9 during the biosynthesis of the non-ribosomally synthesized calcium-
CC       dependent antibiotic (CDA), a 11-residue acidic lipopeptide lactone.
CC   -!- The enzyme is able to hydroxylate only the free L-asparagine, since
CC       it hydroxylates neither a CDA analog with unmodified Asn at position
CC       9 nor a peptidyl-carrier-protein (PCP)-bound asparagine.
CC   -!- The enzyme is not active toward D-asparagine.
DR   Q9Z4Z5, ASNO_STRCO ;
//
ID   1.14.12.1
DE   Anthranilate 1,2-dioxygenase (deaminating, decarboxylating).
AN   Anthranilate hydroxylase.
AN   Anthranilic acid hydroxylase.
AN   Anthranilic hydroxylase.
CA   Anthranilate + NAD(P)H + O(2) = catechol + CO(2) + NAD(P)(+) + NH(3).
CF   Iron.
//
ID   1.14.12.2
DE   Transferred entry: 1.14.13.35.
//
ID   1.14.12.3
DE   Benzene 1,2-dioxygenase.
AN   Benzene hydroxylase.
CA   Benzene + NADH + O(2) = cis-cyclohexa-3,5-diene-1,2-diol + NAD(+).
CF   FAD; Iron; Iron-sulfur.
CC   -!- A system, containing a reductase which is an iron-sulfur flavoprotein
CC       (FAD), an iron-sulfur oxygenase and ferredoxin.
PR   PROSITE; PDOC00493;
DR   Q07944, BEDC1_PSEPU;  Q07945, BEDC2_PSEPU;  A5W4F2, BNZA_PSEP1 ;
DR   P0C618, BNZA_PSEPU ;  A5W4F1, BNZB_PSEP1 ;  P0C619, BNZB_PSEPU ;
//
ID   1.14.12.4
DE   3-hydroxy-2-methylpyridinecarboxylate dioxygenase.
AN   Methylhydroxypyridine carboxylate dioxygenase.
AN   Methylhydroxypyridinecarboxylate oxidase.
CA   3-hydroxy-2-methylpyridine-5-carboxylate + NAD(P)H + O(2) =
CA   2-(acetamidomethylene)succinate + NAD(P)(+).
CF   FAD.
//
ID   1.14.12.5
DE   5-pyridoxate dioxygenase.
AN   5-pyridoxate oxidase.
CA   3-hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate + NADPH + O(2) =
CA   2-(acetamidomethylene)-3-(hydroxymethyl)succinate + NADP(+).
CF   Flavoprotein.
//
ID   1.14.12.6
DE   Transferred entry: 1.14.13.66.
//
ID   1.14.12.7
DE   Phthalate 4,5-dioxygenase.
AN   PDO.
AN   Phthalate dioxygenase.
CA   Phthalate + NADH + O(2) = cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-
CA   dicarboxylate + NAD(+).
CF   FMN; Iron; Iron-sulfur.
CC   -!- A system, containing a reductase which is an iron-sulfur flavoprotein
CC       (FMN), an iron-sulfur oxygenase, and no independent ferredoxin.
DR   Q05182, PHT2_PSEPU ;  Q05183, PHT3_PSEPU ;
//
ID   1.14.12.8
DE   4-sulfobenzoate 3,4-dioxygenase.
CA   4-sulfobenzoate + NADH + O(2) = 3,4-dihydroxybenzoate + sulfite + NAD(+).
CF   FMN; Iron; Iron-sulfur.
CC   -!- A system, containing a reductase which is an iron-sulfur flavoprotein
CC       (FMN), an iron-sulfur oxygenase, and no independent ferredoxin.
//
ID   1.14.12.9
DE   4-chlorophenylacetate 3,4-dioxygenase.
CA   4-chlorophenylacetate + NADH + O(2) = 3,4-dihydroxyphenylacetate +
CA   chloride + NAD(+).
CF   Iron.
CC   -!- A system, containing a reductase and an iron-sulfur oxygenase, and no
CC       independent ferredoxin.
CC   -!- Also acts on 4-bromophenyl acetate.
CC   -!- Formerly EC 1.13.99.4.
//
ID   1.14.12.10
DE   Benzoate 1,2-dioxygenase.
AN   Benzoate hydroxylase.
AN   Benzoic hydroxylase.
CA   Benzoate + NADH + O(2) = (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-
CA   carboxylate + NAD(+).
CF   Fe(2+).
CC   -!- A system, containing a reductase which is an iron-sulfur flavoprotein
CC       (FAD), and an iron-sulfur oxygenase.
CC   -!- Formerly EC 1.13.99.2.
PR   PROSITE; PDOC00493;
DR   P07769, BENA_ACIAD ;  P07770, BENB_ACIAD ;
//
ID   1.14.12.11
DE   Toluene dioxygenase.
AN   Toluene 1,2-dioxygenase.
CA   Toluene + NADH + O(2) = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol +
CA   NAD(+).
CC   -!- A system, containing a reductase which is an iron-sulfur flavoprotein
CC       (FAD), an iron-sulfur oxygenase, and a ferredoxin.
CC   -!- Some other aromatic compounds, including ethylbenzene, 4-xylene and
CC       some halogenated toluenes, are converted into the corresponding cis-
CC       dihydrodiols.
DR   A5W4F2, BNZA_PSEP1 ;  P0C618, BNZA_PSEPU ;  A5W4F1, BNZB_PSEP1 ;
DR   P0C619, BNZB_PSEPU ;
//
ID   1.14.12.12
DE   Naphthalene 1,2-dioxygenase.
CA   Naphthalene + NADH + O(2) = (1R,2S)-1,2-dihydronaphthalene-1,2-diol +
CA   NAD(+).
CF   Iron.
CC   -!- Comprises a multicomponent system, containing a reductase that is an
CC       iron-sulfur flavoprotein (FAD; EC 1.18.1.3), an iron-sulfur
CC       oxygenase, and ferredoxin.
PR   PROSITE; PDOC00493;
DR   Q51494, NDOB_PSEAE ;  O07824, NDOB_PSEFL ;  P0A110, NDOB_PSEPU ;
DR   P0A111, NDOB_PSEU8 ;  Q51495, NDOC_PSEAE ;  O07825, NDOC_PSEFL ;
DR   P0A112, NDOC_PSEPU ;  P0A113, NDOC_PSEU8 ;
//
ID   1.14.12.13
DE   2-chlorobenzoate 1,2-dioxygenase.
CA   2-chlorobenzoate + NADH + O(2) = catechol + chloride + NAD(+) + CO(2).
CF   Iron.
DR   Q51601, CBDA_BURCE ;  Q51602, CBDB_BURCE ;
//
ID   1.14.12.14
DE   2-aminobenzenesulfonate 2,3-dioxygenase.
AN   2-aminosulfobenzene 2,3-dioxygenase.
CA   2-aminobenzenesulfonate + NADH + O(2) = 2,3-dihydroxybenzenesulfonate +
CA   NH(3) + NAD(+).
//
ID   1.14.12.15
DE   Terephthalate 1,2-dioxygenase.
AN   1,4-dicarboxybenzoate 1,2-dioxygenase.
AN   Benzene-1,4-dicarboxylate 1,2-dioxygenase.
CA   Terephthalate + NADH + O(2) = (1R,6S)-dihydroxycyclohexa-2,4-diene-1,4-
CA   dicarboxylate + NAD(+).
CC   -!- In Comamonas testoteroni, contains a Rieske [2Fe-2S] center.
//
ID   1.14.12.16
DE   2-hydroxyquinoline 5,6-dioxygenase.
AN   2-oxo-1,2-dihydroquinoline 5,6-dioxygenase.
AN   Quinolin-2(1H)-one 5,6-dioxygenase.
AN   Quinolin-2-ol 5,6-dioxygenase.
CA   Quinolin-2-ol + NADH + O(2) = 2,5,6-trihydroxy-5,6-dihydroquinoline +
CA   NAD(+).
CC   -!- 3-methylquinolin-2-ol, quinolin-8-ol and quinolin-2,8-diol are also
CC       substrates.
CC   -!- Quinolin-2-ols exist largely as their quinolin-2(1H)-one tautomers.
//
ID   1.14.12.17
DE   Nitric oxide dioxygenase.
AN   NOD.
CA   2 NO + 2 O(2) + NAD(P)H = 2 NO(3)(-) + NAD(P)(+).
CF   FAD; Heme.
CC   -!- It has been proposed that FAD functions as the electron carrier from
CC       NADPH to the ferric heme prosthetic group.
DR   Q9UAG7, FHBA_DICDI ;  Q54D73, FHBB_DICDI ;  Q03331, FHP_CANNO  ;
DR   Q9URY5, FHP_SCHPO  ;  P39676, FHP_YEAST  ;  E1F8Q4, HMP1_GIAIA ;
DR   E1F8H4, HMP2_GIAIA ;  Q81T23, HMP_BACAN  ;  Q73B49, HMP_BACC1  ;
DR   Q81FW4, HMP_BACCR  ;  Q9RC40, HMP_BACHD  ;  Q6HLA6, HMP_BACHK  ;
DR   P49852, HMP_BACSU  ;  Q7WHW5, HMP_BORBR  ;  Q7TTP2, HMP_BORPA  ;
DR   Q7TTP0, HMP_BORPE  ;  Q8GAZ4, HMP_BURST  ;  Q7NSD8, HMP_CHRVO  ;
DR   P39662, HMP_CUPNH  ;  Q9RYR5, HMP_DEIRA  ;  Q47266, HMP_DICD3  ;
DR   Q7ABK6, HMP_ECO57  ;  Q8FF30, HMP_ECOL6  ;  P24232, HMP_ECOLI  ;
DR   Q6D245, HMP_ERWCT  ;  C6LR75, HMP_GIAIB  ;  E2RTZ4, HMP_GIAIC  ;
DR   Q8ETH0, HMP_OCEIH  ;  Q7N215, HMP_PHOLL  ;  Q6LM37, HMP_PHOPR  ;
DR   Q9I0H4, HMP_PSEAE  ;  Q88PP0, HMP_PSEPK  ;  Q7WUM8, HMP_RHIME  ;
DR   Q7UIY1, HMP_RHOBA  ;  Q57LF5, HMP_SALCH  ;  Q5PIH6, HMP_SALPA  ;
DR   Q8Z4M3, HMP_SALTI  ;  P26353, HMP_SALTY  ;  Q7C0F9, HMP_SHIFL  ;
DR   Q9KMY3, HMP_VIBCH  ;  P40609, HMP_VIBPA  ;  Q8DCU2, HMP_VIBVU  ;
DR   Q7MH09, HMP_VIBVY  ;  Q9PH91, HMP_XYLFA  ;  Q87F90, HMP_XYLFT  ;
DR   Q8ZCR0, HMP_YERPE  ;
//
ID   1.14.12.18
DE   Biphenyl 2,3-dioxygenase.
AN   Biphenyl dioxygenase.
CA   Biphenyl + NADH + O(2) = (1S,2R)-3-phenylcyclohexa-3,5-diene-1,2-diol +
CA   NAD(+).
CF   Iron.
CC   -!- The enzyme from Burkholderia fungorum strain LB400 (previously
CC       Pseudomonas sp.) is part of a multicomponent system composed of an
CC       NADH:ferredoxin oxidoreductase (FAD cofactor), a [2Fe-2S] Rieske-type
CC       ferredoxin, and a terminal oxygenase that contains a [2Fe-2S] Rieske-
CC       type iron-sulfur cluster and a catalytic mononuclear nonheme iron
CC       center.
CC   -!- Chlorine-substituted biphenyls can also act as substrates.
CC   -!- Similar to the three-component enzyme systems EC 1.14.12.3 and
CC       EC 1.14.12.11.
PR   PROSITE; PDOC00493;
DR   Q52438, BPHA1_PSES1;  Q52439, BPHA2_PSES1;  P37333, BPHA_BURXL ;
DR   Q46372, BPHA_COMTE ;  Q52028, BPHA_PSEPS ;  P37334, BPHE_BURXL ;
DR   Q46373, BPHE_COMTE ;
//
ID   1.14.12.19
DE   3-phenylpropanoate dioxygenase.
AN   3-phenylpropionate dioxygenase.
AN   Hca dioxygenase.
AN   HcaA1A2CD.
CA   (1) 3-phenylpropanoic acid + NADH + O(2) = cis-3-(2-carboxyethyl)-3,5-
CA   cyclohexadiene-1,2-diol + NAD(+).
CA   (2) Cinnamic acid + NADH + O(2) = cis-3-(2-carboxyethenyl)-3,5-
CA   cyclohexadiene-1,2-diol + NAD(+).
CF   Iron.
CC   -!- This enzyme catalyzes the insertion of both atoms of molecular oxygen
CC       into positions 2 and 3 of the phenyl ring of 3-phenylpropanoate.
CC   -!- The product, 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate,
CC       is then converted into 3-(2,3-dihydroxyphenyl)propanoate, by a
CC       dehydrogenase, with the concomitant regeneration of NADH.
CC   -!- The enzyme also acts on (2E)-3-phenylprop-2-enoate (cinnamate).
PR   PROSITE; PDOC00493;
DR   P0ABR6, HCAE_ECO57 ;  A8A344, HCAE_ECOHS ;  P0ABR5, HCAE_ECOLI ;
DR   Q7N4W0, HCAE_PHOLL ;  Q31XV2, HCAE_SHIBS ;  Q0T1Y1, HCAE_SHIF8 ;
DR   Q83K39, HCAE_SHIFL ;  Q3YZ15, HCAE_SHISS ;  A7ZPY2, HCAF_ECO24 ;
DR   B7LDD1, HCAF_ECO55 ;  Q8XA73, HCAF_ECO57 ;  B5Z112, HCAF_ECO5E ;
DR   B7NRI8, HCAF_ECO7I ;  B7M7P2, HCAF_ECO8A ;  C4ZXB4, HCAF_ECOBW ;
DR   B1XB14, HCAF_ECODH ;  A8A345, HCAF_ECOHS ;  B1IVT8, HCAF_ECOLC ;
DR   Q47140, HCAF_ECOLI ;  B7N6C6, HCAF_ECOLU ;  B6I5B2, HCAF_ECOSE ;
DR   B1LNJ5, HCAF_ECOSM ;  Q7N4V9, HCAF_PHOLL ;  Q31XV1, HCAF_SHIBS ;
DR   Q0T1Y0, HCAF_SHIF8 ;  Q83K38, HCAF_SHIFL ;  Q3YZ14, HCAF_SHISS ;
//
ID   1.14.12.20
DE   Pheophorbide a oxygenase.
AN   PaO.
AN   PAO.
AN   Pheide a monooxygenase.
AN   Pheide a oxygenase.
CA   Pheophorbide a + NADPH + O(2) = red chlorophyll catabolite + NADP(+).
CC   -!- Catalyzes a key reaction in chlorophyll degradation, which occurs
CC       during leaf senescence and fruit ripening in higher plants.
CC   -!- Requires reduced ferredoxin, which is generated either by NADPH
CC       through the pentose-phosphate pathway or by the action of photosystem
CC       I.
CC   -!- While still attached to this enzyme, the product is rapidly converted
CC       into primary fluorescent chlorophyll catabolite by the action of
CC       EC 1.3.1.80.
CC   -!- Pheophorbide b acts as an inhibitor.
CC   -!- In (18)O(2) labelling experiments, only the aldehyde oxygen is
CC       labelled, suggesting that the other oxygen atom may originate from
CC       H(2)O.
DR   Q9FYC2, PAO_ARATH  ;
//
ID   1.14.12.21
DE   Benzoyl-CoA 2,3-dioxygenase.
AN   Benzoyl-CoA dioxygenase/reductase.
CA   Benzoyl-CoA + NADPH + O(2) = 2,3-dihydro-2,3-dihydroxybenzoyl-CoA +
CA   NADP(+).
CF   FAD and iron-sulfur and iron.
CC   -!- The enzyme is involved in aerobic benzoate metabolism in Azoarcus
CC       evansii.
CC   -!- BoxB functions as the oxygenase part of benzoyl-CoA oxygenase in
CC       conjunction with BoxA, the reductase component, which upon binding of
CC       benzoyl-CoA, transfers two electrons to the ring in the course of
CC       dioxygenation.
CC   -!- Formerly EC 1.14.12.n1.
DR   Q9AIX6, BOXA_AZOEV ;  Q9AIX7, BOXB_AZOEV ;
//
ID   1.14.12.22
DE   Carbazole 1,9a-dioxygenase.
AN   CARDO.
CA   9H-carbazole + NAD(P)H + O(2) = 2'-aminobiphenyl-2,3-diol + NAD(P)(+).
CF   Iron; Iron-sulfur.
CC   -!- This enzyme catalyzes the first reaction in the pathway of carbazole
CC       degradation.
CC   -!- The enzyme attacks at the 1 and 9a positions of carbazole, resulting
CC       in the formation of a highly unstable hemiaminal intermediate that
CC       undergoes a spontaneous cleavage and rearomatization, resulting in
CC       2'-aminobiphenyl-2,3-diol.
CC   -!- In most bacteria the enzyme is a complex composed of a terminal
CC       oxygenase, a ferredoxin, and a ferredoxin reductase.
CC   -!- The terminal oxygenase component contains a nonheme iron center and a
CC       Rieske [2Fe-2S] iron-sulfur cluster.
//
ID   1.14.12.n1
DE   Transferred entry: 1.14.12.21.
//
ID   1.14.13.1
DE   Salicylate 1-monooxygenase.
AN   Salicylate hydroxylase.
AN   Salicylic hydroxylase.
CA   Salicylate + NADH + O(2) = catechol + NAD(+) + H(2)O + CO(2).
CF   FAD.
DR   P23262, NHG1_PSEPU ;  Q53552, NHG2_PSEPU ;
//
ID   1.14.13.2
DE   4-hydroxybenzoate 3-monooxygenase.
AN   p-hydroxybenzoate hydroxylase.
AN   p-hydroxybenzoic acid hydroxylase.
AN   Para-hydroxybenzoate hydroxylase.
CA   4-hydroxybenzoate + NADPH + O(2) = protocatechuate + NADP(+) + H(2)O.
CF   FAD.
CC   -!- Most enzymes from Pseudomonas are highly specific for NAD(P)H (cf.
CC       EC 1.14.13.33).
DR   Q03298, PHHY_ACIAD ;  P20586, PHHY_PSEAE ;  P00438, PHHY_PSEFL ;
//
ID   1.14.13.3
DE   4-hydroxyphenylacetate 3-monooxygenase.
AN   4 HPA 3-hydroxylase.
AN   4-hydroxyphenylacetic acid-3-hydroxylase.
AN   p-hydroxyphenylacetate 3-hydroxylase.
CA   4-hydroxyphenylacetate + NADH + O(2) = 3,4-dihydroxyphenylacetate +
CA   NAD(+) + H(2)O.
CF   FAD.
//
ID   1.14.13.4
DE   Melilotate 3-monooxygenase.
AN   2-hydroxyphenylpropionate hydroxylase.
AN   Melilotate hydroxylase.
AN   Melilotic hydroxylase.
CA   3-(2-hydroxyphenyl)propanoate + NADH + O(2) = 3-(2,3-
CA   dihydroxyphenyl)propanoate + NAD(+) + H(2)O.
CF   FAD.
//
ID   1.14.13.5
DE   Imidazoleacetate 4-monooxygenase.
AN   Imidazoleacetate hydroxylase.
AN   Imidazoleacetic monooxygenase.
CA   4-imidazoleacetate + NADH + O(2) = 5-hydroxy-4-imidazoleacetate + NAD(+)
CA   + H(2)O.
CF   FAD.
CC   -!- Formerly EC 1.14.1.5.
//
ID   1.14.13.6
DE   Orcinol 2-monooxygenase.
AN   Orcinol hydroxylase.
CA   Orcinol + NADH + O(2) = 2,3,5-trihydroxytoluene + NAD(+) + H(2)O.
CF   FAD.
//
ID   1.14.13.7
DE   Phenol 2-monooxygenase.
AN   Phenol hydroxylase.
AN   Phenol o-hydroxylase.
CA   Phenol + NADPH + O(2) = catechol + NADP(+) + H(2)O.
CF   FAD.
CC   -!- Also active with resorcinol and 2-methylphenol.
DR   P19729, DMPK_PSEUF ;  Q7WTJ6, DMPL_ACICP ;  P19730, DMPL_PSEUF ;
DR   P19731, DMPM_PSEUF ;  P19732, DMPN_PSEUF ;  P19733, DMPO_PSEUF ;
DR   Q7WTJ2, DMPP_ACICP ;  P19734, DMPP_PSEUF ;  P15245, PH2M_TRICU ;
DR   P31020, PHEA_PSEUE ;  Q01551, TBUD_BURPI ;
//
ID   1.14.13.8
DE   Flavin-containing monooxygenase.
AN   Dimethylaniline monooxygenase (N-oxide-forming).
AN   Dimethylaniline N-oxidase.
AN   Dimethylaniline oxidase.
AN   DMA oxidase.
AN   FAD-containing monooxygenase.
AN   Flavin mixed function oxidase.
AN   Flavin monooxygenase.
AN   FMO.
AN   Methylphenyltetrahydropyridine N-monooxygenase.
AN   Mixed-function amine oxidase.
AN   N,N-dimethylaniline monooxygenase.
AN   Ziegler's enzyme.
CA   N,N-dimethylaniline + NADPH + O(2) = N,N-dimethylaniline N-oxide +
CA   NADP(+) + H(2)O.
CF   FAD.
CC   -!- A broad spectrum monooxygenase that accepts substrates as diverse as
CC       hydrazines, phosphines, boron-containing compounds, sulfides,
CC       selenides, iodide, as well as primary, secondary and tertiary amines.
CC   -!- Is distinct from other monooxygenases in that the enzyme forms a
CC       relatively stable hydroperoxy flavin intermediate.
CC   -!- Generally converts nucleophilic heteroatom-containing chemicals and
CC       drugs into harmless, readily excreted metabolites.
CC   -!- For example, N-oxygenation is largely responsible for the
CC       detoxification of the dopaminergic neurotoxin 1-methyl-4-phenyl-
CC       1,2,3,6-tetrahydropyridine (MPTP).
CC   -!- Formerly EC 1.13.12.11.
DR   Q95LA2, FMO1_CANFA ;  P49328, FMO1_CAVPO ;  Q01740, FMO1_HUMAN ;
DR   P50285, FMO1_MOUSE ;  P16549, FMO1_PIG   ;  P17636, FMO1_RABIT ;
DR   P36365, FMO1_RAT   ;  P36366, FMO2_CAVPO ;  Q8HZ69, FMO2_GORGO ;
DR   Q99518, FMO2_HUMAN ;  Q28505, FMO2_MACMU ;  Q8K2I3, FMO2_MOUSE ;
DR   Q8HZ70, FMO2_PANTR ;  Q5REK0, FMO2_PONAB ;  P17635, FMO2_RABIT ;
DR   Q6IRI9, FMO2_RAT   ;  Q8HYJ9, FMO3_BOVIN ;  Q95LA1, FMO3_CANFA ;
DR   P31513, FMO3_HUMAN ;  Q8SPQ7, FMO3_MACMU ;  P97501, FMO3_MOUSE ;
DR   Q7YS44, FMO3_PANTR ;  P32417, FMO3_RABIT ;  Q9EQ76, FMO3_RAT   ;
DR   P31512, FMO4_HUMAN ;  Q8VHG0, FMO4_MOUSE ;  P36367, FMO4_RABIT ;
DR   Q8K4B7, FMO4_RAT   ;  P49109, FMO5_CAVPO ;  P49326, FMO5_HUMAN ;
DR   P97872, FMO5_MOUSE ;  Q04799, FMO5_RABIT ;  Q8K4C0, FMO5_RAT   ;
DR   O60774, FMO6_HUMAN ;
//
ID   1.14.13.9
DE   Kynurenine 3-monooxygenase.
AN   Kynurenine 3-hydroxylase.
CA   L-kynurenine + NADPH + O(2) = 3-hydroxy-L-kynurenine + NADP(+) + H(2)O.
CF   FAD.
CC   -!- Formerly EC 1.14.1.2 and EC 1.99.1.5.
DR   A2Q9N7, KMO1_ASPNC ;  A2QMH1, KMO2_ASPNC ;  A2QPD9, KMO3_ASPNC ;
DR   Q86PM2, KMO_AEDAE  ;  Q7Q6A7, KMO_ANOGA  ;  Q751I2, KMO_ASHGO  ;
DR   A1CT23, KMO_ASPCL  ;  B0Y7C3, KMO_ASPFC  ;  Q4WN75, KMO_ASPFU  ;
DR   Q2UPP1, KMO_ASPOR  ;  Q0CRI5, KMO_ASPTN  ;  A8Y432, KMO_CAEBR  ;
DR   Q21795, KMO_CAEEL  ;  Q5A7M3, KMO_CANAL  ;  Q2GQG8, KMO_CHAGB  ;
DR   P0CO49, KMO_CRYNB  ;  P0CO48, KMO_CRYNJ  ;  Q11PP7, KMO_CYTH3  ;
DR   Q1RLY6, KMO_DANRE  ;  Q6BV21, KMO_DEBHA  ;  Q54RE8, KMO_DICDI  ;
DR   A1Z746, KMO_DROME  ;  Q5B2N0, KMO_EMENI  ;  A5FMP6, KMO_FLAJ1  ;
DR   A6H1P4, KMO_FLAPJ  ;  A0M4X2, KMO_GRAFK  ;  O15229, KMO_HUMAN  ;
DR   A5IG23, KMO_LEGPC  ;  Q5WY16, KMO_LEGPL  ;  Q91WN4, KMO_MOUSE  ;
DR   Q1DDU6, KMO_MYXXD  ;  A1DMD5, KMO_NEOFI  ;  Q7S3C9, KMO_NEUCR  ;
DR   Q0V5K1, KMO_PHANO  ;  A3LNF8, KMO_PICST  ;  Q9MZS9, KMO_PIG    ;
DR   Q84HF5, KMO_PSEFL  ;  O88867, KMO_RAT    ;  A8LVF4, KMO_SALAI  ;
DR   A4XD40, KMO_SALTO  ;  B2FL98, KMO_STRMK  ;  Q4P0N0, KMO_USTMA  ;
DR   Q8PM34, KMO_XANAC  ;  Q3BV41, KMO_XANC5  ;  Q4UT92, KMO_XANC8  ;
DR   B0RV00, KMO_XANCB  ;  Q8PAD3, KMO_XANCP  ;  Q2P316, KMO_XANOM  ;
DR   B2SIT6, KMO_XANOP  ;  Q5H038, KMO_XANOR  ;  Q6DIZ8, KMO_XENTR  ;
DR   Q6C9M8, KMO_YARLI  ;  P38169, KMO_YEAST  ;
//
ID   1.14.13.10
DE   2,6-dihydroxypyridine 3-monooxygenase.
CA   2,6-dihydroxypyridine + NADH + O(2) = 2,3,6-trihydroxypyridine + NAD(+) +
CA   H(2)O.
CF   Flavoprotein.
//
ID   1.14.13.11
DE   Trans-cinnamate 4-monooxygenase.
AN   CA4H.
AN   Cinnamate 4-hydroxylase.
AN   Cinnamate 4-monooxygenase.
AN   Cinnamic acid 4-hydroxylase.
AN   Cinnamic acid 4-monooxygenase.
CA   Trans-cinnamate + NADPH + O(2) = 4-hydroxycinnamate + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- Also acts on NADH, more slowly.
PR   PROSITE; PDOC00081;
DR   P92994, TCMO_ARATH ;  P48522, TCMO_CATRO ;  O81928, TCMO_CICAR ;
DR   Q96423, TCMO_GLYEC ;  Q04468, TCMO_HELTU ;  P37114, TCMO_MEDSA ;
DR   Q43067, TCMO_PEA   ;  Q43033, TCMO_PETCR ;  Q43054, TCMO_POPKI ;
DR   O24312, TCMO_POPTM ;  Q9AR74, TCMO_RUTGR ;  Q42797, TCMO_SOYBN ;
DR   P37115, TCMO_VIGRR ;  Q43240, TCMO_ZINEL ;
//
ID   1.14.13.12
DE   Benzoate 4-monooxygenase.
AN   Benzoate 4-hydroxylase.
AN   Benzoate-p-hydroxylase.
AN   Benzoate-para-hydroxylase.
AN   Benzoic acid 4-hydroxylase.
AN   p-hydroxybenzoate hydroxylase.
CA   Benzoate + NADPH + O(2) = 4-hydroxybenzoate + NADP(+) + H(2)O.
CF   5,6,7,8-tetrahydropteridine; Iron.
PR   PROSITE; PDOC00081;
DR   P17549, CP53_ASPNG ;
//
ID   1.14.13.13
DE   Calcidiol 1-monooxygenase.
AN   25-hydroxycholecalciferol 1-monooxygenase.
AN   25-hydroxycholecalciferol-1-hydroxylase.
AN   25-hydroxyvitamin D-1 alpha hydroxylase.
AN   25-OHD-1 alpha-hydroxylase.
CA   Calcidiol + NADPH + O(2) = calcitriol + NADP(+) + H(2)O.
CF   Heme-thiolate.
PR   PROSITE; PDOC00081;
DR   O15528, CP27B_HUMAN;  O35084, CP27B_MOUSE;  O35132, CP27B_RAT  ;
//
ID   1.14.13.14
DE   Trans-cinnamate 2-monooxygenase.
AN   Cinnamic 2-hydroxylase.
AN   Cinnamic acid 2-hydroxylase.
CA   Trans-cinnamate + NADPH + O(2) = 2-hydroxycinnamate + NADP(+) + H(2)O.
//
ID   1.14.13.15
DE   Cholestanetriol 26-monooxygenase.
AN   5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase.
AN   5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol hydroxylase.
AN   Cholestanetriol 26-hydroxylase.
AN   Cholesterol 27-hydroxylase.
AN   Cytochrome P450 27A1'.
AN   Sterol 26-hydroxylase.
AN   Sterol 27-hydroxylase.
AN   Vitamin D(3) 25-hydroxylase.
CA   5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol + NADPH + O(2) = (25R)-
CA   5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- Requires ferrodoxin.
CC   -!- Acts on cholesterol, cholest-5-en-3-beta,7-alpha-diol, 7-alpha-
CC       hydroxycholest-4-en-3-one, 5-beta-cholestane-3-alpha,7-alpha-diol as
CC       well as 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol.
CC   -!- With cholesterol as well as 26-hydroxycholesterol, 24-hydroxy- and
CC       25-hydroxycholesterol are also formed.
CC   -!- With prolonged treatment, 26-hydroxycholesterol is converted into the
CC       corresponding 27-aldehyde and 27-oic acid.
DR   Q02318, CP27A_HUMAN;  Q9DBG1, CP27A_MOUSE;  P17177, CP27A_RABIT;
DR   P17178, CP27A_RAT  ;  O46658, CP2DP_PIG  ;  Q6VVX0, CP2R1_HUMAN;
DR   Q6VVW9, CP2R1_MOUSE;  C4B644, CPVDH_PSEAH;
//
ID   1.14.13.16
DE   Cyclopentanone monooxygenase.
AN   Cyclopentanone 1,2-monooxygenase.
CA   Cyclopentanone + NADPH + O(2) = 5-valerolactone + NADP(+) + H(2)O.
DR   Q8GAW0, CPNB_COMS9 ;  Q937L5, CPNB_COMTE ;
//
ID   1.14.13.17
DE   Cholesterol 7-alpha-monooxygenase.
AN   Cholesterol 7-alpha-hydroxylase.
CA   Cholesterol + NADPH + O(2) = 7-alpha-hydroxycholesterol + NADP(+) +
CA   H(2)O.
CF   Heme-thiolate.
PR   PROSITE; PDOC00081;
DR   P46634, CP7A1_CRIGR;  P22680, CP7A1_HUMAN;  Q64505, CP7A1_MOUSE;
DR   O46491, CP7A1_PIG  ;  P51542, CP7A1_RABIT;  P18125, CP7A1_RAT  ;
//
ID   1.14.13.18
DE   4-hydroxyphenylacetate 1-monooxygenase.
AN   4-HPA 1-hydroxylase.
AN   4-hydroxyphenylacetate 1-hydroxylase.
AN   4-hydroxyphenylacetic 1-hydroxylase.
CA   4-hydroxyphenylacetate + NAD(P)H + O(2) = homogentisate + NAD(P)(+) +
CA   H(2)O.
CF   FAD.
CC   -!- Also acts on 4-hydroxyhydratropate forming 2-methylhomogentisate and
CC       on 4-hydroxyphenoxyacetate forming hydroquinone and glycolate.
//
ID   1.14.13.19
DE   Taxifolin 8-monooxygenase.
CA   Taxifolin + NAD(P)H + O(2) = 2,3-dihydrogossypetin + NAD(P)(+) + H(2)O.
CF   Flavoprotein.
CC   -!- Converts a flavanol into a flavanone.
CC   -!- Also acts on fustin, but not on catechin, quercetin or
CC       mollisacacidin.
//
ID   1.14.13.20
DE   2,4-dichlorophenol 6-monooxygenase.
AN   2,4-dichlorophenol hydroxylase.
CA   2,4-dichlorophenol + NADPH + O(2) = 3,5-dichlorocatechol + NADP(+) +
CA   H(2)O.
CF   FAD.
CC   -!- Also acts, more slowly, on 4-chlorophenol and 4-chloro-2-
CC       methylphenol.
CC   -!- NADH can act instead of NADPH, but more slowly.
DR   P27138, TFDB_CUPPJ ;  Q8KN28, TFDB_DELAC ;
//
ID   1.14.13.21
DE   Flavonoid 3'-monooxygenase.
AN   Flavonoid 3'-hydroxylase.
CA   A flavonoid + NADPH + O(2) = a 3'-hydroxyflavonoid + NADP(+) + H(2)O.
CC   -!- Acts on a number of flavonoids, including naringenin and
CC       dihydrokaempferol.
CC   -!- Does not act on 4-coumarate or 4-coumaroyl-CoA.
DR   Q9SD85, F3PH_ARATH ;  Q9SBQ9, F3PH_PETHY ;
//
ID   1.14.13.22
DE   Cyclohexanone monooxygenase.
AN   Cyclohexanone 1,2-monooxygenase.
AN   Cyclohexanone oxygenase.
AN   Cyclohexanone:NADPH:oxygen oxidoreductase (6-hydroxylating, 1,2-
AN   lactonizing).
CA   Cyclohexanone + NADPH + O(2) = hexano-6-lactone + NADP(+) + H(2)O.
CF   FAD.
CC   -!- In the catalytic mechanism of this enzyme, the nucleophilic species
CC       that attacks the carbonyl group is a peroxyflavin intermediate that
CC       is generated by reaction of the enzyme-bound flavin cofactor with
CC       NAD(P)H and oxygen.
CC   -!- This enzyme is able to catalyze a wide range of oxidative reactions,
CC       including enantioselective Baeyer-Villiger reactions, sulfoxidations,
CC       amine oxidations and epoxidations.
DR   P12015, CYMO_ACISP ;
//
ID   1.14.13.23
DE   3-hydroxybenzoate 4-monooxygenase.
AN   3-hydroxybenzoate 4-hydroxylase.
CA   3-hydroxybenzoate + NADPH + O(2) = 3,4-dihydroxybenzoate + NADP(+) +
CA   H(2)O.
CF   FAD.
CC   -!- Also acts on a number of analogs of 3-hydroxybenzoate substituted in
CC       the 2, 4, 5 and 6 positions.
CC   -!- Formerly EC 1.14.99.13.
//
ID   1.14.13.24
DE   3-hydroxybenzoate 6-monooxygenase.
AN   3-hydroxybenzoate 6-hydroxylase.
AN   3-hydroxybenzoic acid-6-hydroxylase.
CA   3-hydroxybenzoate + NADH + O(2) = 2,5-dihydroxybenzoate + NAD(+) + H(2)O.
CF   FAD.
CC   -!- Also acts on a number of analogs of 3-hydroxybenzoate substituted in
CC       the 2, 4, 5 and 6 positions.
CC   -!- NADPH can act instead of NADH, more slowly.
DR   Q9F131, 3HBH1_PSEAC;  Q0QFQ1, 3HBH2_PSEAC;  Q5EXK1, 3HBH_KLEOX ;
DR   Q3S4B7, 3HBH_POLNA ;
//
ID   1.14.13.25
DE   Methane monooxygenase (soluble).
AN   Methane hydroxylase.
CA   Methane + NAD(P)H + O(2) = methanol + NAD(P)(+) + H(2)O.
CC   -!- The enzyme is soluble, in contrast to the particulate enzyme,
CC       EC 1.14.18.3.
CC   -!- Broad specificity; many alkanes can be hydroxylated, and alkenes are
CC       converted into the corresponding epoxides; CO is oxidized to CO(2),
CC       ammonia is oxidized to hydroxylamine, and some aromatic compounds and
CC       cyclic alkanes can also be hydroxylated, but more slowly.
DR   P22869, MEMA_METCA ;  P27353, MEMA_METTR ;  P18798, MEMB_METCA ;
DR   P27354, MEMB_METTR ;  P11987, MEMG_METCA ;  P27355, MEMG_METTR ;
DR   P22868, MMOC_METCA ;  Q53563, MMOC_METTR ;
//
ID   1.14.13.26
DE   Phosphatidylcholine 12-monooxygenase.
AN   Oleate Delta(12)-hydroxylase.
AN   Ricinoleic acid synthase.
CA   1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + NADH + O(2) = 1-acyl-2-
CA   ((S)-12-hydroxyoleoyl)-sn-glycero-3-phosphocholine + NAD(+) + H(2)O.
//
ID   1.14.13.27
DE   4-aminobenzoate 1-monooxygenase.
AN   4-aminobenzoate dehydrogenase.
AN   4-aminobenzoate hydroxylase.
CA   4-aminobenzoate + NAD(P)H + O(2) = 4-hydroxyaniline + NAD(P)(+) + H(2)O +
CA   CO(2).
CF   FAD.
CC   -!- Acts on anthranilate and 4-aminosalicylate but not on salicylate (cf.
CC       EC 1.14.13.1).
//
ID   1.14.13.28
DE   3,9-dihydroxypterocarpan 6A-monooxygenase.
AN   3,9-dihydroxypterocarpan 6A-hydroxylase.
CA   (6aR,11aR)-3,9-dihydroxypterocarpan + NADPH + O(2) = (6aS,11aS)-3,6a,9-
CA   trihydroxypterocarpan + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- The product of the reaction is the biosynthetic precursor of the
CC       phytoalexin glyceollin in soybean.
PR   PROSITE; PDOC00081;
//
ID   1.14.13.29
DE   4-nitrophenol 2-monooxygenase.
AN   4-nitrophenol hydroxylase.
AN   4-nitrophenol-2-hydroxylase.
CA   4-nitrophenol + NADH + O(2) = 4-nitrocatechol + NAD(+) + H(2)O.
CF   FAD.
//
ID   1.14.13.30
DE   Leukotriene-B(4) 20-monooxygenase.
AN   Leukotriene-B(4) 20-hydroxylase.
AN   Leukotriene-B(4) omega-hydroxylase.
AN   LTB(4) 20-hydroxylase.
AN   LTB(4) omega-hydroxylase.
CA   (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate +
CA   NADPH + O(2) = (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-
CA   6,8,10,14-tetraenoate + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- Not identical with EC 1.14.13.34.
PR   PROSITE; PDOC00081;
DR   P78329, CP4F2_HUMAN;  Q08477, CP4F3_HUMAN;  Q99N16, CP4F3_MOUSE;
DR   Q3MID2, CP4F3_RAT  ;  Q9EP75, CP4FE_MOUSE;
//
ID   1.14.13.31
DE   2-nitrophenol 2-monooxygenase.
AN   Nitrophenol oxygenase.
CA   2-nitrophenol + NADPH + O(2) = catechol + nitrite + NADP(+) + H(2)O.
CC   -!- Involved in the metabolism of nitro-aromatic compounds by a strain of
CC       Pseudomonas putida.
//
ID   1.14.13.32
DE   Albendazole monooxygenase.
AN   Albendazole sulfoxidase.
CA   Albendazole + NADPH + O(2) = albendazole S-oxide + NADP(+) + H(2)O.
CF   FAD.
DR   P08684, CP3A4_HUMAN;
//
ID   1.14.13.33
DE   4-hydroxybenzoate 3-monooxygenase (NAD(P)H).
AN   4-hydroxybenzoate 3-hydroxylase.
CA   4-hydroxybenzoate + NAD(P)H + O(2) = 3,4-dihydroxybenzoate + NAD(P)(+) +
CA   H(2)O.
CF   FAD.
CC   -!- The enzyme from Corynebacterium cyclohexanicum is highly specific for
CC       4-hydroxybenzoate, but uses NADH and NADPH at approximately equal
CC       rates (cf. EC 1.14.13.2).
CC   -!- It is less specific for NADPH than EC 1.14.13.2.
//
ID   1.14.13.34
DE   Leukotriene-E(4) 20-monooxygenase.
AN   Leukotriene-E(4) omega-hydroxylase.
CA   (7E,9E,11Z,14Z)-(5S,6R)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14-
CA   tetraenoate + NADPH + O(2) = 20-hydroxyleukotriene E(4) + NADP(+) +
CA   H(2)O.
CC   -!- Also acts on N-acetyl-leukotriene E(4), more slowly.
CC   -!- Not identical with EC 1.14.13.30.
//
ID   1.14.13.35
DE   Anthranilate 3-monooxygenase (deaminating).
AN   Anthranilate 2,3-hydroxylase (deaminating).
AN   Anthranilate hydroxylase.
CA   Anthranilate + NADPH + O(2) = 2,3-dihydroxybenzoate + NADP(+) + NH(3).
CC   -!- The enzyme from Aspergillus niger is an iron protein; that from the
CC       yeast Trichosporon cutaneum is a flavoprotein (FAD).
CC   -!- Formerly EC 1.14.12.2.
//
ID   1.14.13.36
DE   5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase.
AN   5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase.
CA   Trans-5-O-(4-coumaroyl)-D-quinate + NADPH + O(2) = trans-5-O-caffeoyl-D-
CA   quinate + NADP(+) + H(2)O.
CC   -!- Also acts on trans-5-O-(4-coumaroyl)shikimate.
//
ID   1.14.13.37
DE   Methyltetrahydroprotoberberine 14-monooxygenase.
AN   (S)-cis-N-methyltetrahydroprotoberberine-14-hydroxylase.
AN   Methyltetrahydroprotoberberine 14-hydroxylase.
CA   (S)-N-methylcanadine + NADPH + O(2) = allocryptopine + NADP(+) + H(2)O.
CF   Heme-thiolate.
PR   PROSITE; PDOC00081;
//
ID   1.14.13.38
DE   Anhydrotetracycline monooxygenase.
AN   Anhydrotetracycline oxygenase.
AN   ATC oxygenase.
CA   Anhydrotetracycline + NADPH + O(2) = 12-dehydrotetracycline + NADP(+) +
CA   H(2)O.
CC   -!- Involved in the biosynthesis of tetracyclines in Streptomyces sp.
//
ID   1.14.13.39
DE   Nitric-oxide synthase.
AN   Endothelium-derived relaxation factor-forming enzyme.
AN   Endothelium-derived relaxing factor synthase.
AN   NADPH-diaphorase.
AN   Nitric-oxide synthetase.
AN   NO synthase.
CA   L-arginine + n NADPH + n H(+) + m O(2) = citrulline + nitric oxide +
CA   n NADP(+).
CC   -!- The enzyme in brain, but not that induced in lung or liver by
CC       endotoxin, requires calcium.
CC   -!- The stoichiometry is not clear, but may involve a two-electron and a
CC       one-electron oxidation step.
DR   Q66GP9, NOS1_ARATH ;  P29475, NOS1_HUMAN ;  Q9Z0J4, NOS1_MOUSE ;
DR   O19132, NOS1_RABIT ;  P29476, NOS1_RAT   ;  Q29498, NOS1_SHEEP ;
DR   Q27995, NOS2_BOVIN ;  O62699, NOS2_CANFA ;  Q28314, NOS2_CAPHI ;
DR   Q92037, NOS2_CARAU ;  O54705, NOS2_CAVPO ;  Q90703, NOS2_CHICK ;
DR   P35228, NOS2_HUMAN ;  O46660, NOS2_MACMU ;  P29477, NOS2_MOUSE ;
DR   Q92091, NOS2_ONCMY ;  P79290, NOS2_PIG   ;  O19114, NOS2_RABIT ;
DR   Q06518, NOS2_RAT   ;  P29473, NOS3_BOVIN ;  Q9TUX8, NOS3_CANFA ;
DR   P97270, NOS3_CAVPO ;  P29474, NOS3_HUMAN ;  P70313, NOS3_MOUSE ;
DR   Q28969, NOS3_PIG   ;  Q62600, NOS3_RAT   ;  P79209, NOS3_SHEEP ;
DR   B1B557, NOSL_BOMMO ;  O61608, NOS_ANOST  ;  Q8T8C0, NOS_BOMMO  ;
DR   Q27571, NOS_DROME  ;  O61309, NOS_LYMST  ;  Q6YPG5, NOS_ORYSJ  ;
DR   Q26240, NOS_RHOPR  ;  Q9I9M2, NOS_SQUAC  ;
//
ID   1.14.13.40
DE   Anthraniloyl-CoA monooxygenase.
AN   2-aminobenzoyl-CoA monooxygenase/reductase.
CA   2-aminobenzoyl-CoA + 2 NAD(P)H + O(2) = 2-amino-5-oxocyclohex-1-
CA   enecarboxyl-CoA + H(2)O + 2 NAD(P)(+).
CF   FAD.
CC   -!- The non-aromatic product is unstable and releases CO(2) and NH(3),
CC       forming 1,4-cyclohexanedione.
//
ID   1.14.13.41
DE   Tyrosine N-monooxygenase.
AN   CYP79A1.
AN   Tyrosine N-hydroxylase.
CA   (1) L-tyrosine + O(2) + NADPH = N-hydroxy-L-tyrosine + NADP(+) + H(2)O.
CA   (2) N-hydroxy-L-tyrosine + O(2) + NADPH = N,N-dihydroxy-L-tyrosine +
CA   NADP(+) + H(2)O.
CA   (3) N,N-dihydroxy-L-tyrosine = (Z)-(4-hydroxyphenylacetaldehyde oxime) +
CA   CO(2) + H(2)O.
CF   Heme-thiolate.
CC   -!- Involved in the biosynthesis of the cyanogenic glucoside dhurrin in
CC       sorghum, along with EC 1.14.13.68 and EC 2.4.1.85.
CC   -!- Some 2-(4-hydroxyphenyl)-1-nitroethane is formed as a side product.
PR   PROSITE; PDOC00081;
DR   Q43135, C79A1_SORBI;
//
ID   1.14.13.42
DE   Deleted entry.
//
ID   1.14.13.43
DE   Questin monooxygenase.
AN   Questin oxygenase.
CA   Questin + NADPH + O(2) = demethylsulochrin + NADP(+) + H(2)O.
CC   -!- The enzyme cleaves the anthraquinone ring of questin to form a
CC       benzophenone.
CC   -!- Involved in the biosynthesis of the seco-anthraquinone (+)-geodin.
//
ID   1.14.13.44
DE   2-hydroxybiphenyl 3-monooxygenase.
CA   2-hydroxybiphenyl + NADH + O(2) = 2,3-dihydroxybiphenyl + NAD(+) + H(2)O.
CC   -!- Also converts 2,2'-dihydroxybiphenyl into 2,2',3-trihydroxy-biphenyl.
//
ID   1.14.13.45
DE   Transferred entry: 1.14.18.2.
//
ID   1.14.13.46
DE   (-)-menthol monooxygenase.
CA   (-)-menthol + NADPH + O(2) = p-menthane-3,8-diol + NADP(+) + H(2)O.
//
ID   1.14.13.47
DE   (S)-limonene 3-monooxygenase.
AN   (-)-limonene 3-hydroxylase.
AN   (-)-limonene 3-monooxygenase.
AN   (-)-limonene,NADPH:oxygen oxidoreductase (3-hydroxylating).
CA   (-)-(S)-limonene + NADPH + O(2) = (-)-trans-isopiperitenol + NADP(+) +
CA   H(2)O.
CF   Heme-thiolate.
CC   -!- High specificity, but NADH can act instead of NADPH, although more
CC       slowly.
PR   PROSITE; PDOC00081;
DR   Q9XHE7, C71DD_MENPI;  Q9XHE6, C71DF_MENPI;  Q6WKY9, C7D95_MENGR;
DR   Q6IV13, C7D95_MENSP;
//
ID   1.14.13.48
DE   (S)-limonene 6-monooxygenase.
AN   (-)-limonene 6-hydroxylase.
AN   (-)-limonene 6-monooxygenase.
AN   (-)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating).
CA   (-)-(S)-limonene + NADPH + O(2) = (-)-trans-carveol + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- High specificity, but NADH can act instead of NADPH, although more
CC       slowly.
PR   PROSITE; PDOC00081;
DR   Q6WKZ1, C71DI_MENGR;  Q9XHE8, C71DI_MENSP;  P11712, CP2C9_HUMAN;
DR   P33261, CP2CJ_HUMAN;  O85057, LIHY_GEOSE ;
//
ID   1.14.13.49
DE   (S)-limonene 7-monooxygenase.
AN   (-)-limonene 7-monooxygenase.
AN   (-)-limonene hydroxylase.
AN   (-)-limonene monooxygenase.
AN   (-)-limonene,NADPH:oxygen oxidoreductase (7-hydroxylating).
CA   (-)-(S)-limonene + NADPH + O(2) = (-)-perillyl alcohol + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- High specificity, but NADH can act instead of NADPH, although more
CC       slowly.
PR   PROSITE; PDOC00081;
DR   P11712, CP2C9_HUMAN;  P33261, CP2CJ_HUMAN;  O85057, LIHY_GEOSE ;
//
ID   1.14.13.50
DE   Pentachlorophenol monooxygenase.
AN   PCB 4-monooxygenase.
AN   PCB4MO.
AN   PCP hydroxylase.
AN   Pentachlorophenol 4-monooxygenase.
AN   Pentachlorophenol dechlorinase.
AN   Pentachlorophenol dehalogenase.
AN   Pentachlorophenol hydroxylase.
CA   (1) Pentachlorophenol + 2 NADPH + O(2) = 2,3,5,6-tetrachlorohydroquinone
CA   + 2 NADP(+) + chloride + H(2)O.
CA   (2) 2,3,5,6-tetrachlorophenol + NADPH + O(2) = 2,3,5,6-
CA   tetrachlorohydroquinone + NADP(+) + H(2)O.
CF   FAD.
CC   -!- The enzyme displaces a diverse range of substituents from the
CC       4-position of polyhalogenated phenols but requires that a halogen
CC       substituent be present at the 2-position.
CC   -!- The enzyme converts many polyhalogenated phenols into hydroquinones,
CC       and requires that a halogen substituent be present at C-2.
CC   -!- If C-4 carries a halogen substituent, reaction 1 is catalyzed, e.g.
CC       2,4,6-triiodophenol is oxidized to 2,6-diiodohydroquinone; if C-4 is
CC       unsubstituted, reaction 2 is catalyzed.
DR   P42535, PCPB_SPHCR ;
//
ID   1.14.13.51
DE   6-oxocineole dehydrogenase.
CA   6-oxocineole + NADPH + O(2) = 1,6,6-trimethyl-2,7-
CA   dioxabicyclo[3.2.2]nonan-3-one + NADP(+) + H(2)O.
CC   -!- The product undergoes non-enzymic cleavage and subsequent ring
CC       closure to form the lactone 4,5-dihydro-5,5-dimethyl-4-
CC       (3-oxobutyl)furan-2(3H)-one.
//
ID   1.14.13.52
DE   Isoflavone 3'-hydroxylase.
CA   Formononetin + NADPH + O(2) = calycosin + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- Also acts on biochanin A and other isoflavones with a 4'-methoxy
CC       group.
CC   -!- Involved in the biosynthesis of the pterocarpin phytoalexins
CC       medicarpin and maackiain.
PR   PROSITE; PDOC00081;
//
ID   1.14.13.53
DE   4'-methoxyisoflavone 2'-hydroxylase.
AN   Isoflavone 2'-hydroxylase.
AN   Isoflavone 2'-monooxygenase.
CA   Formononetin + NADPH + O(2) = 2'-hydroxyformononetin + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- Acts on isoflavones with a 4'-methoxy group, such as formononetin and
CC       biochanin A.
CC   -!- Involved in the biosynthesis of the pterocarpin phytoalexins
CC       medicarpin and maackiain.
CC   -!- EC 1.14.13.89 is less specific and acts on other isoflavones as well
CC       as 4'-methoxyisoflavones.
PR   PROSITE; PDOC00081;
//
ID   1.14.13.54
DE   Ketosteroid monooxygenase.
AN   Steroid-ketone monooxygenase.
CA   (1) Ketosteroid + NADPH + O(2) = steroid ester/lactone + NADP(+) + H(2)O.
CA   (2) Progesterone + NADPH + O(2) = testosterone acetate + NADP(+) + H(2)O.
CA   (3) Androstenedione + NADPH + O(2) = testololactone + NADP(+) + H(2)O.
CA   (4) 17-alpha-hydroxyprogesterone + NADPH + O(2) = androstenedione +
CA   NADP(+) + H(2)O + acetate.
CF   FAD.
CC   -!- A single FAD-containing enzyme catalyzes three types of monooxygenase
CC       (Baeyer-Villiger oxidation) reaction.
CC   -!- The oxidative esterification of a number of derivatives of
CC       progesterone to produce the corresponding 17-alpha-hydroxysteroid
CC       17-acetate ester, such as testosterone acetate, is shown in reaction
CC       (2).
CC   -!- The oxidative lactonization of a number of derivatives of
CC       androstenedione to produce the 13,17-secoandrosteno-17,13-alpha-
CC       lactone, such as testololactone, is shown in reaction (3).
CC   -!- The oxidative cleavage of the 17-beta-side-chain of 17-alpha-
CC       hydroxyprogesterone to produce androstenedione and acetate is shown
CC       in reaction (4).
CC   -!- reaction (2) is also catalyzed by EC 1.14.99.4 and reactions (3) and
CC       (4) correspond to that catalyzed by EC 1.14.99.12.
CC   -!- The possibility that a single enzyme is responsible for the reactions
CC       ascribed to EC 1.14.99.4 and EC 1.14.99.12 in other tissues cannot be
CC       excluded.
//
ID   1.14.13.55
DE   Protopine 6-monooxygenase.
AN   Protopine 6-hydroxylase.
CA   Protopine + NADPH + O(2) = 6-hydroxyprotopine + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- Involved in benzophenanthridine alkaloid synthesis in higher plants.
PR   PROSITE; PDOC00081;
//
ID   1.14.13.56
DE   Dihydrosanguinarine 10-monooxygenase.
AN   Dihydrosanguinarine 10-hydroxylase.
CA   Dihydrosanguinarine + NADPH + O(2) = 10-hydroxydihydrosanguinarine +
CA   NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- Involved in benzophenanthridine alkaloid synthesis in higher plants.
PR   PROSITE; PDOC00081;
//
ID   1.14.13.57
DE   Dihydrochelirubine 12-monooxygenase.
AN   Dihydrochelirubine 12-hydroxylase.
CA   Dihydrochelirubine + NADPH + O(2) = 12-hydroxydihydrochelirubine +
CA   NADP(+) + H(2)O.
CF   Heme-thiolate.
PR   PROSITE; PDOC00081;
//
ID   1.14.13.58
DE   Benzoyl-CoA 3-monooxygenase.
AN   Benzoyl-CoA 3-hydroxylase.
CA   Benzoyl-CoA + NADPH + O(2) = 3-hydroxybenzoyl-CoA + NADP(+) + H(2)O.
CF   FMN or FAD.
CC   -!- Benzoate is not a substrate.
//
ID   1.14.13.59
DE   L-lysine 6-monooxygenase (NADPH).
AN   Lysine N(6)-hydroxylase.
CA   L-lysine + NADPH + O(2) = N(6)-hydroxy-L-lysine + NADP(+) + H(2)O.
CF   FAD.
CC   -!- The enzyme from strain EN 222 of Escherichia coli is highly specific
CC       for L-lysine; L-ornithine and L-homolysine are, for example,
CC       not substrates.
DR   P11295, IUCD_ECOLX ;  Q7TYQ9, MBTG_MYCBO ;  Q73XY8, MBTG_MYCPA ;
DR   Q1B6B3, MBTG_MYCSS ;  O05820, MBTG_MYCTU ;
//
ID   1.14.13.60
DE   27-hydroxycholesterol 7-alpha-monooxygenase.
AN   27-hydroxycholesterol 7-alpha-hydroxylase.
CA   27-hydroxycholesterol + NADPH + O(2) = 7-alpha,27-dihydroxycholesterol +
CA   NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- The enzyme from mammalian liver differs from EC 1.14.13.17 in having
CC       no activity toward cholesterol.
PR   PROSITE; PDOC00081;
//
ID   1.14.13.61
DE   2-hydroxyquinoline 8-monooxygenase.
AN   2-oxo-1,2-dihydroquinoline 8-monooxygenase.
CA   Quinolin-2-ol + NADH + O(2) = quinolin-2,8-diol + NAD(+) + H(2)O.
CF   Iron.
CC   -!- Quinolin-2-ol exists largely as the quinolin-2(1H)-one tautomer.
//
ID   1.14.13.62
DE   4-hydroxyquinoline 3-monooxygenase.
AN   1-H-4-oxoquinoline 3-monooxygenase.
AN   Quinolin-4(1H)-one 3-monooxygenase.
CA   Quinolin-4-ol + NADH + O(2) = quinolin-3,4-diol + NAD(+) + H(2)O.
CC   -!- Quinolin-4-ol exists largely as the quinolin-4(1H)-one tautomer.
//
ID   1.14.13.63
DE   3-hydroxyphenylacetate 6-hydroxylase.
AN   3-hydroxyphenylacetate 6-monooxygenase.
CA   3-hydroxyphenylacetate + NAD(P)H + O(2) = 2,5-dihydroxyphenylacetate +
CA   NAD(P)(+) + H(2)O.
CF   FAD.
CC   -!- 3-hydroxyphenylacetate 6-hydroxylase from Flavobacterium sp. is
CC       highly specific for 3-hydroxyphenylacetate and uses NADH and NADPH as
CC       electron donors with similar efficiency.
//
ID   1.14.13.64
DE   4-hydroxybenzoate 1-hydroxylase.
AN   4-hydroxybenzoate 1-monooxygenase.
CA   4-hydroxybenzoate + NAD(P)H + O(2) = hydroquinone + NAD(P)(+) + H(2)O +
CA   CO(2).
CF   FAD.
CC   -!- The enzyme from Candida parapsilosis is specific for
CC       4-hydroxybenzoate derivatives and prefers NADH to NADPH as electron
CC       donor.
//
ID   1.14.13.65
DE   Deleted entry.
//
ID   1.14.13.66
DE   2-hydroxycyclohexanone 2-monooxygenase.
CA   2-hydroxycyclohexan-1-one + NADPH + O(2) = 6-hydroxyhexan-6-olide +
CA   NADP(+) + H(2)O.
CC   -!- The product decomposes spontaneously to 6-oxohexanoic acid (adipic
CC       semialdehyde).
CC   -!- Formerly EC 1.14.12.6.
//
ID   1.14.13.67
DE   Quinine 3-monooxygenase.
AN   Nifedipine oxidase.
AN   Quinine 3-hydroxylase.
CA   Quinine + NADPH + O(2) = 3-hydroxyquinine + NADP(+) + H(2)O.
CF   Heme-thiolate.
PR   PROSITE; PDOC00081;
DR   P08684, CP3A4_HUMAN;
//
ID   1.14.13.68
DE   4-hydroxyphenylacetaldehyde oxime monooxygenase.
AN   4-hydroxybenzeneacetaldehyde oxime monooxygenase.
AN   CYP71E1.
AN   Cytochrome P450-II-dependent monooxygenase.
CA   (Z)-4-hydroxyphenylacetaldehyde oxime + NADPH + O(2) = (S)-4-
CA   hydroxymandelonitrile + NADP(+) + 2 H(2)O.
CF   Heme-thiolate.
CC   -!- Involved in the biosynthesis of the cyanogenic glucoside dhurrin in
CC       sorghum, along with EC 1.14.13.41 and EC 2.4.1.85.
PR   PROSITE; PDOC00081;
DR   O48958, C71E1_SORBI;
//
ID   1.14.13.69
DE   Alkene monooxygenase.
AN   Alkene epoxygenase.
CA   Propene + NADH + O(2) = 1,2-epoxypropane + NAD(+) + H(2)O.
CF   Iron.
CC   -!- The enzyme from Xanthobacter sp. strain Py2 is a multicomponent
CC       enzyme comprising:
CC       (1) an NADH reductase, which provides the reductant for O(2)
CC       activation.
CC       (2) a Rieske-type ferredoxin, which is an electron-transfer protein.
CC       (3) an oxygenase, which contains the catalytic center for alkene
CC       epoxidation.
CC       (4) a small protein of unknown function that is essential for
CC       activity.
CC   -!- The enzyme oxygenates C(2) to C(6) aliphatic alkenes.
CC   -!- With 1,2-epoxypropane as substrate, the stereospecificity of the
CC       epoxypropane formed is 95% (R) and 5% (S).
//
ID   1.14.13.70
DE   Sterol 14-demethylase.
AN   Cytochrome P450 51.
AN   Lanosterol 14-alpha-demethylase.
AN   Lanosterol 14-demethylase.
AN   Obtusufoliol 14-demethylase.
AN   Sterol 14-alpha-demethylase.
CA   Obtusifoliol + 3 O(2) + 3 NADPH = 4-alpha-methyl-5-alpha-ergosta-
CA   8,14,24(28)-trien-3-beta-ol + formate + 3 NADP(+) + 4 H(2)O.
CF   Heme-thiolate.
CC   -!- The enzyme (P450) catalyzes successive hydroxylations of the
CC       14-alpha-methyl group and C-15, followed by elimination as formate
CC       leaving the 14(15) double bond.
CC   -!- This enzyme acts on a range of steroids with a 14-alpha-methyl group.
PR   PROSITE; PDOC00081;
DR   Q4PJW3, CP51A_BOVIN;  Q16850, CP51A_HUMAN;  Q4R8S6, CP51A_MACFA;
DR   Q8K0C4, CP51A_MOUSE;  O46420, CP51A_PIG  ;  Q5RE72, CP51A_PONAB;
DR   Q64654, CP51A_RAT  ;  Q759W0, CP51_ASHGO ;  P10613, CP51_CANAL ;
DR   P50859, CP51_CANGA ;  P14263, CP51_CANTR ;  Q9UVC3, CP51_CUNEL ;
DR   Q1ZXH9, CP51_DICDI ;  Q02315, CP51_ISSOR ;  Q5UQI3, CP51_MIMIV ;
DR   P0A513, CP51_MYCBO ;  P0A512, CP51_MYCTU ;  Q5IZM4, CP51_MYCVP ;
DR   Q12664, CP51_PENIT ;  Q09736, CP51_SCHPO ;  P93846, CP51_SORBI ;
DR   Q7Z1V1, CP51_TRYCR ;  O14442, CP51_UNCNE ;  P49602, CP51_USTMA ;
DR   P93596, CP51_WHEAT ;  P10614, CP51_YEAST ;
//
ID   1.14.13.71
DE   N-methylcoclaurine 3'-monooxygenase.
AN   (S)-N-methylcoclaurine 3'-hydroxylase.
AN   Cytochrome P450 80B1.
AN   N-methylcoclaurine 3'-hydroxylase.
CA   (S)-N-methylcoclaurine + NADPH + O(2) = (S)-3'-hydroxy-N-methylcoclaurine
CA   + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- A P450 protein involved in benzylisoquinoline alkaloid synthesis in
CC       higher plants.
PR   PROSITE; PDOC00081;
DR   O64899, C80B1_ESCCA;  Q9FXW4, C80B2_COPJA;  O64900, C80B2_ESCCA;
//
ID   1.14.13.72
DE   Methylsterol monooxygenase.
AN   4-methylsterol oxidase.
AN   Methylsterol hydroxylase.
CA   (1) 4,4-dimethyl-5-alpha-cholest-7-en-3-beta-ol + NAD(P)H + O(2) =
CA   4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholest-7-en-3-beta-ol +
CA   NAD(P)(+) + H(2)O.
CA   (2) 4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholest-7-en-3-beta-ol +
CA   NAD(P)H + O(2) = 3-beta-hydroxy-4-beta-methyl-5-alpha-cholest-7-ene-4-
CA   alpha-carbaldehyde + NAD(P)(+) + 2 H(2)O.
CA   (3) 3-beta-hydroxy-4-beta-methyl-5-alpha-cholest-7-ene-4-alpha-
CA   carbaldehyde + NAD(P)H + O(2) = 3-beta-hydroxy-4-beta-methyl-5-alpha-
CA   cholest-7-ene-4-alpha-carboxylate + NAD(P)(+) + H(2)O.
CC   -!- Requires cytochrome b5.
CC   -!- Also acts on 4-alpha-methyl-5-alpha-cholest-7-en-3-beta-ol.
CC   -!- The sterol can be based on cycloartenol as well as lanosterol.
CC   -!- Formerly EC 1.14.99.16.
DR   Q55D52, ER25A_DICDI;  Q55D54, ER25B_DICDI;  O59933, ERG25_CANAL;
DR   Q5ZLL6, ERG25_CHICK;  Q7ZW77, ERG25_DANRE;  Q15800, ERG25_HUMAN;
DR   Q4R4Q4, ERG25_MACFA;  Q9CRA4, ERG25_MOUSE;  Q6UGB2, ERG25_PIG  ;
DR   Q5R574, ERG25_PONAB;  O35532, ERG25_RAT  ;  Q9UUH4, ERG25_SCHPO;
DR   P53045, ERG25_YEAST;
//
ID   1.14.13.73
DE   Tabersonine 16-hydroxylase.
CA   Tabersonine + NADPH + O(2) = 16-hydroxytabersonine + NADP(+) + H(2)O.
CF   Heme-thiolate.
PR   PROSITE; PDOC00081;
DR   P98183, C71DC_CATRO;
//
ID   1.14.13.74
DE   7-deoxyloganin 7-hydroxylase.
CA   7-deoxyloganin + NADPH + O(2) = loganin + NADP(+) + H(2)O.
CF   Heme-thiolate.
PR   PROSITE; PDOC00081;
//
ID   1.14.13.75
DE   Vinorine hydroxylase.
CA   Vinorine + NADPH + O(2) = vomilenine + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- Forms a stage in the biosynthesis of the indole alkaloid ajmaline.
PR   PROSITE; PDOC00081;
//
ID   1.14.13.76
DE   Taxane 10-beta-hydroxylase.
AN   5-alpha-taxadienol-10-beta-hydroxylase.
CA   Taxa-4(20),11-dien-5-alpha-yl acetate + NADPH + O(2) = 10-beta-
CA   hydroxytaxa-4(20),11-dien-5-alpha-yl acetate + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- Involved in the biosynthesis of the diterpenoid antineoplastic drug
CC       taxol (paclitaxel).
PR   PROSITE; PDOC00081;
DR   Q9AXM6, T10H_TAXCU ;
//
ID   1.14.13.77
DE   Taxane 13-alpha-hydroxylase.
CA   Taxa-4(20),11-dien-5-alpha-ol + NADPH + O(2) = taxa-4(20),11-dien-5-
CA   alpha,13-alpha-diol + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- Involved in the biosynthesis of the diterpenoid antineoplastic drug
CC       taxol (paclitaxel).
PR   PROSITE; PDOC00081;
DR   Q8W4T9, T13H_TAXCU ;
//
ID   1.14.13.78
DE   Ent-kaurene oxidase.
CA   (1) Ent-kaur-16-ene + NADPH + O(2) = ent-kaur-16-en-19-ol + NADP(+) +
CA   H(2)O.
CA   (2) Ent-kaur-16-en-19-ol + NADPH + O(2) = ent-kaur-16-en-19-al + NADP(+)
CA   + 2 H(2)O.
CA   (3) Ent-kaur-16-en-19-al + NADPH + O(2) = ent-kaur-16-en-19-oate +
CA   NADP(+) + H(2)O.
CC   -!- Requires cytochrome P450.
CC   -!- Catalyzes three sucessive oxidations of the 4-methyl group of ent-
CC       kaurene giving kaurenoic acid.
PR   PROSITE; PDOC00081;
DR   Q93ZB2, KO1_ARATH  ;  O94142, KO1_GIBFU  ;  Q701P2, KO1_GIBIN  ;
//
ID   1.14.13.79
DE   Ent-kaurenoic acid oxidase.
CA   (1) Ent-kaur-16-en-19-oate + NADPH + O(2) = ent-7-alpha-hydroxykaur-16-
CA   en-19-oate + NADP(+) + H(2)O.
CA   (2) Ent-7-alpha-hydroxykaur-16-en-19-oate + NADPH + O(2) = gibberellin
CA   A(12) aldehyde + NADP(+) + 2 H(2)O.
CA   (3) Gibberellin A(12) aldehyde + NADPH + O(2) = gibberellin A(12) +
CA   NADP(+) + H(2)O.
CC   -!- Requires cytochrome P450.
CC   -!- Catalyzes three sucessive oxidations of ent-kaurenoic acid.
CC   -!- The second step includes a ring-B contraction giving the gibbane
CC       skeleton.
CC   -!- In Cucurbita maxima, ent-6-alpha,7-alpha-dihydroxykaur-16-en-19-oate
CC       is also formed.
PR   PROSITE; PDOC00081;
DR   O23051, KAO1_ARATH ;  Q9AXH9, KAO1_HORVU ;  Q9C5Y2, KAO2_ARATH ;
//
ID   1.14.13.80
DE   (R)-limonene 6-monooxygenase.
AN   (+)-limonene 6-monooxygenase.
AN   (+)-limonene-6-hydroxylase.
CA   (+)-(R)-limonene + NADPH + O(2) = (+)-trans-carveol + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- The reaction is stereospecific with over 95% yield of (+)-trans-
CC       carveol from (R)-limonene.
CC   -!- (S)-Limonene, the substrate for EC 1.14.13.48 is not a substrate.
CC   -!- Forms part of the carvone biosynthesis pathway in Carum carvi
CC       (caraway) seeds.
PR   PROSITE; PDOC00081;
DR   P11712, CP2C9_HUMAN;  P33261, CP2CJ_HUMAN;
//
ID   1.14.13.81
DE   Magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase.
AN   Mg-protoporphyrin IX monomethyl ester oxidative cyclase.
CA   (1) Magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O(2) =
CA   13(1)-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP(+) +
CA   H(2)O.
CA   (2) 13(1)-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH
CA   + O(2) = 13(1)-oxo-magnesium-protoporphyrin IX 13-monomethyl ester +
CA   NADP(+) + 2 H(2)O.
CA   (3) 13(1)-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH +
CA   O(2) = divinylprotochlorophyllide + NADP(+) + 2 H(2)O.
CF   Iron.
CC   -!- The cyclase activity in Chlamydomonas reinhardtii is associated
CC       exclusively with the membranes, whereas that from cucumber cotyledons
CC       requires both membrane and soluble fractions for activity.
DR   Q8YX57, ACSF1_NOSS1;  P72584, ACSF1_SYNY3;  Q8DJ05, ACSF1_THEEB;
DR   Q8YVU4, ACSF2_NOSS1;  P74134, ACSF2_SYNY3;  Q8DI68, ACSF2_THEEB;
DR   Q8YRZ2, ACSF3_NOSS1;  A5EQ73, ACSF_BRASB ;  A4YNQ1, ACSF_BRASO ;
DR   Q9TLR8, ACSF_CYACA ;  Q85FX6, ACSF_CYAME ;  Q7NFA1, ACSF_GLOVI ;
DR   Q6B8U1, ACSF_GRATL ;  P51277, ACSF_PORPU ;  Q1XDK9, ACSF_PORYE ;
DR   A3PD22, ACSF_PROM0 ;  A8G4Z1, ACSF_PROM2 ;  A2CDU0, ACSF_PROM3 ;
DR   A9BAI8, ACSF_PROM4 ;  A2BWG6, ACSF_PROM5 ;  Q31AS9, ACSF_PROM9 ;
DR   Q7VBV0, ACSF_PROMA ;  Q7V3Y9, ACSF_PROMM ;  Q7V1M1, ACSF_PROMP ;
DR   A2BR98, ACSF_PROMS ;  Q2ISZ6, ACSF_RHOP2 ;  Q6N9J7, ACSF_RHOPA ;
DR   Q132P2, ACSF_RHOPS ;  B3Q7D4, ACSF_RHOPT ;  Q8VPB5, ACSF_RUBGE ;
DR   Q31LY2, ACSF_SYNE7 ;  Q5MZZ2, ACSF_SYNP6 ;  A5GKR3, ACSF_SYNPW ;
DR   Q7U6Y8, ACSF_SYNPX ;  A5GU20, ACSF_SYNR3 ;  Q0IAL0, ACSF_SYNS3 ;
DR   Q3AK18, ACSF_SYNSC ;  Q118B4, ACSF_TRIEI ;  Q9M591, CRD1_ARATH ;
DR   Q9LD46, CRD1_CHLRE ;  Q945B7, CRD1_EUPES ;  Q6SJV8, CRD1_GOSHI ;
DR   Q5EFU4, CRD1_HORVU ;  Q9AR22, CTH1_CHLRE ;
//
ID   1.14.13.82
DE   Vanillate monooxygenase.
AN   4-hydroxy-3-methoxybenzoate demethylase.
AN   Vanillate demethylase.
CA   Vanillate + O(2) + NADH = 3,4-dihydroxybenzoate + NAD(+) + H(2)O +
CA   formaldehyde.
CC   -!- Forms part of the vanillin degradation pathway in Arthrobacter sp.
CC   -!- Formerly EC 1.2.3.12.
PR   PROSITE; PDOC00493;
DR   P12609, VANA_PSES9 ;  O05616, VANA_PSEUH ;
//
ID   1.14.13.83
DE   Precorrin-3B synthase.
AN   Precorrin-3X synthase.
CA   Precorrin-3A + NADH + O(2) = precorrin-3B + NAD(+) + H(2)O.
CF   Iron-sulfur.
CC   -!- An oxygen atom from dioxygen is incorporated into the macrocycle at
CC       C-20.
CC   -!- In the aerobic cobalamin biosynthesis pathway, four enzymes are
CC       involved in the conversion of precorrin-3A to precorrin-6A.
CC   -!- This enzyme carries out the first of the four steps, yielding
CC       precorrin-3B as the product.
CC   -!- This is followed by three methylation reactions, which introduce a
CC       methyl group at C-17 (CobJ; EC 2.1.1.131), C-11 (CobM; 2.1.1.133) and
CC       C-1 (CobF; EC 2.1.1.152) of the macrocycle, giving rise to precorrin-
CC       4, precorrin-5 and precorrin-6A, respectively.
DR   P21637, COBG_PSEDE ;
//
ID   1.14.13.84
DE   4-hydroxyacetophenone monooxygenase.
AN   HAPMO.
CA   (4-hydroxyphenyl)ethan-1-one + NADPH + O(2) = 4-hydroxyphenyl acetate +
CA   NADP(+) + H(2)O.
CF   FAD.
CC   -!- The enzyme from Pseudomonas fluorescens ACB catalyzes the conversion
CC       of a wide range of acetophenone derivatives.
CC   -!- Highest activity occurs with compounds bearing an electron-donating
CC       substituent at the para position of the aromatic ring.
CC   -!- In the absence of substrate, the enzyme can act as an NADPH oxidase
CC       (EC 1.6.3.1).
DR   Q93TJ5, HAPMO_PSEFL;
//
ID   1.14.13.85
DE   Glyceollin synthase.
AN   Dimethylallyl-3,6a,9-trihydroxypterocarpan cyclase.
CA   2-(or 4-)dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH +
CA   O(2) = glyceollin + NADP(+) + 2 H(2)O.
CF   Heme-thiolate.
CC   -!- Glyceollins II and III are formed from 2-dimethylallyl-(6aS,11aS)-
CC       3,6a,9-trihydroxypterocarpan whereas glyceollin I is formed from the
CC       4-isomer.
PR   PROSITE; PDOC00081;
//
ID   1.14.13.86
DE   2-hydroxyisoflavanone synthase.
AN   2-HIS.
CA   Apigenin + 2 NADPH + O(2) = 2-hydroxy-2,3-dihydrogenistein + 2 NADP(+) +
CA   H(2)O.
CF   Heme-thiolate.
CC   -!- EC 4.2.1.105 acts on 2-hydroxy-2,3-dihydrogenistein with loss of
CC       water and formation of genistein; this may occur spontaneously.
PR   PROSITE; PDOC00081;
DR   Q9SWR5, C93C1_SOYBN;
//
ID   1.14.13.87
DE   Licodione synthase.
AN   (2S)-flavanone 2-hydroxylase.
CA   Liquiritigenin + NADPH + O(2) = licodione + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- It probably forms 2-hydroxyliquiritigenin which spontaneously forms
CC       licodione.
CC   -!- NADH can act instead of NADPH, but more slowly.
PR   PROSITE; PDOC00081;
DR   P93149, C93B1_GLYEC;
//
ID   1.14.13.88
DE   Flavonoid 3',5'-hydroxylase.
AN   F3',5'H.
AN   F3'5'H.
CA   (1) A flavanone + NADPH + O(2) = a 3'-hydroxyflavanone + NADP(+) + H(2)O.
CA   (2) A 3'-hydroxyflavanone + NADPH + O(2) = a 3',5'-dihydroxyflavanone +
CA   NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- The 3',5'-dihydroxyflavanone is formed via the 3'-hydroxyflavanone.
CC   -!- In Petunia hybrida the enzyme acts on naringenin, eriodictyol,
CC       dihydroquercetin (taxifolin) and dihydrokaempferol (aromadendrin).
CC   -!- The enzyme catalyzes the hydroxylation of 5,7,4'-trihydroxyflavanone
CC       (naringenin) at either the 3' position to form eriodictyol or at both
CC       the 3' and 5' positions to form 5,7,3',4',5'-pentahydroxyflavanone
CC       (dihydrotricetin).
CC   -!- The enzyme also catalyzes the hydroxylation of
CC       3,5,7,3',4'-pentahydroxyflavanone (taxifolin) at the 5' position,
CC       forming ampelopsin.
CC   -!- NADH is not a good substitute for NADPH.
PR   PROSITE; PDOC00081;
DR   P48418, C75A1_PETHY;  P37120, C75A2_SOLME;  P48419, C75A3_PETHY;
DR   Q96581, C75A4_GENTR;  Q96418, C75A5_EUSGR;  O04773, C75A6_CAMME;
DR   O04790, C75A7_EUSGR;
//
ID   1.14.13.89
DE   Isoflavone 2'-hydroxylase.
AN   CYP Ge-3.
AN   CYP81E1.
AN   Isoflavone 2'-monooxygenase.
CA   An isoflavone + NADPH + O(2) = a 2'-hydroxyisoflavone + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- Acts on daidzein, formononetin and genistein.
CC   -!- EC 1.14.13.53 has the same reaction but is more specific as it
CC       requires a 4'-methoxyisoflavone.
PR   PROSITE; PDOC00081;
DR   P93147, C81E1_GLYEC;
//
ID   1.14.13.90
DE   Zeaxanthin epoxidase.
AN   Zea-epoxidase.
CA   (1) Zeaxanthin + NAD(P)H + O(2) = antheraxanthin + NAD(P)(+) + H(2)O.
CA   (2) Antheraxanthin + NAD(P)H + O(2) = violaxanthin + NAD(P)(+) + H(2)O.
CF   FAD.
CC   -!- Active under conditions of low light.
CC   -!- Along with EC 1.10.99.3, this enzyme forms part of the xanthophyll
CC       (or violaxanthin) cycle, which is involved in protecting the plant
CC       against damage by excess light.
CC   -!- It will also epoxidize lutein in some higher-plant species.
DR   Q96375, ABA2_CAPAN ;  Q40412, ABA2_NICPL ;  O81360, ABA2_PRUAR ;
DR   P93236, ABA2_SOLLC ;  Q9FGC7, ZEP_ARATH  ;  Q0JCU7, ZEP_ORYSJ  ;
//
ID   1.14.13.91
DE   Deoxysarpagine hydroxylase.
AN   DOSH.
CA   10-deoxysarpagine + NADPH + O(2) = sarpagine + NADP(+) + H(2)O.
CF   Heme-thiolate.
PR   PROSITE; PDOC00081;
//
ID   1.14.13.92
DE   Phenylacetone monooxygenase.
AN   PAMO.
CA   Phenylacetone + NADPH + O(2) = benzyl acetate + NADP(+) + H(2)O.
CF   FAD.
CC   -!- NADH cannot replace NADPH as coenzyme.
CC   -!- In addition to phenylacetone, which is the best substrate found to
CC       date, this Baeyer-Villiger monooxygenase can oxidize other aromatic
CC       ketones (1-(4-hydroxyphenyl)propan-2-one, 1-(4-hydroxyphenyl)propan-
CC       2-one and 3-phenylbutan-2-one), some alipatic ketones (e.g. dodecan-
CC       2-one) and sulfides (e.g. 1-methyl-4-(methylsulfanyl)benzene).
DR   Q47PU3, PAMO_THEFY ;
//
ID   1.14.13.93
DE   (+)-abscisic acid 8'-hydroxylase.
AN   (+)-ABA 8'-hydroxylase.
AN   ABA 8'-hydroxylase.
CA   (+)-abscisate + NADPH + O(2) = 8'-hydroxyabscisate + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- Catalyzes the first step in the oxidative degradation of abscisic
CC       acid and is considered to be the pivotal enzyme in controlling the
CC       rate of degradation of this plant hormone.
CC   -!- CO inhibits the reaction, but its effects can be reversed by the
CC       presence of blue light.
CC   -!- The 8'-hydroxyabscisate formed can be converted into (-)-phaseic
CC       acid, most probably spontaneously.
CC   -!- Other enzymes involved in the abscisic-acid biosynthesis pathway are
CC       EC 1.1.1.288, EC 1.2.3.14 and EC 1.13.11.51.
PR   PROSITE; PDOC00081;
DR   Q949P1, ABAH1_ARATH;  Q09J79, ABAH1_ORYSI;  Q05JG2, ABAH1_ORYSJ;
DR   O81077, ABAH2_ARATH;  Q09J78, ABAH2_ORYSI;  Q6ZDE3, ABAH2_ORYSJ;
DR   Q9FH76, ABAH3_ARATH;  A2Z212, ABAH3_ORYSI;  Q0J185, ABAH3_ORYSJ;
DR   Q9LJK2, ABAH4_ARATH;
//
ID   1.14.13.94
DE   Lithocholate 6-beta-hydroxylase.
AN   6-beta-hydroxylase.
AN   Cytochrome P450 3A10/lithocholic acid 6-beta-hydroxylase.
AN   Lithocholate 6-beta-monooxygenase.
CA   Lithocholate + NADPH + O(2) = 6-beta-hydroxylithocholate + NADP(+) +
CA   H(2)O.
CF   Heme-thiolate.
CC   -!- Expression of the gene for this enzyme is 50-fold higher in male
CC       compared to female hamsters.
PR   PROSITE; PDOC00081;
DR   Q64148, CP3AA_MESAU;
//
ID   1.14.13.95
DE   7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase.
AN   7-alpha-hydroxy-4-cholesten-3-one 12-alpha-monooxygenase.
AN   HCO 12-alpha-hydroxylase.
AN   Sterol 12-alpha-hydroxylase.
CA   7-alpha-hydroxycholest-4-en-3-one + NADPH + O(2) = 7-alpha,12-alpha-
CA   dihydroxycholest-4-en-3-one + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- Requires EC 1.6.2.4 and cytochrome b5 for maximal activity.
CC   -!- Important in bile acid biosynthesis, being responsible for the
CC       balance between the formation of cholic acid and chenodeoxycholic
CC       acid.
PR   PROSITE; PDOC00081;
DR   Q9UNU6, CP8B1_HUMAN;  O88962, CP8B1_MOUSE;  O02766, CP8B1_RABIT;
//
ID   1.14.13.96
DE   5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase.
AN   5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-monooxygenase.
AN   Cytochrome P450 8B1.
AN   Sterol 12-alpha-hydroxylase.
CA   5-beta-cholestane-3-alpha,7-alpha-diol + NADPH + O(2) = 5-beta-
CA   cholestane-3-alpha,7-alpha,12-alpha-triol + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- Key enzyme in the biosynthesis of the bile acid cholic acid
CC       (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanoic acid).
CC   -!- The activity determines the biosynthetic ratio between cholic acid
CC       and chenodeoxycholic acid.
CC   -!- Can also hydroxylate the substrate at the 25 and 26 position, but to
CC       a lesser extent.
PR   PROSITE; PDOC00081;
DR   Q7YRB2, CP8B1_PIG  ;
//
ID   1.14.13.97
DE   Taurochenodeoxycholate 6-alpha-hydroxylase.
AN   Taurochenodeoxycholate 6-alpha-monooxygenase.
CA   (1) Taurochenodeoxycholate + NADPH + O(2) = taurohyocholate + NADP(+) +
CA   H(2)O.
CA   (2) Lithocholate + NADPH + O(2) = hyodeoxycholate + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- Requires cytochrome b5 for maximal activity.
CC   -!- Acts on taurochenodeoxycholate, taurodeoxycholate and less readily on
CC       lithocholate and chenodeoxycholate.
CC   -!- In adult pig (Sus scrofa), hyocholic acid replaces cholic acid as a
CC       primary bile acid.
PR   PROSITE; PDOC00081;
DR   P08684, CP3A4_HUMAN;  Q9GJX5, CP4AL_PIG  ;
//
ID   1.14.13.98
DE   Cholesterol 24-hydroxylase.
AN   Cholesterol 24-monooxygenase.
AN   Cholesterol 24S-hydroxylase.
AN   Cytochrome P450 46A1.
CA   Cholesterol + NADPH + O(2) = (24S)-24-hydroxycholesterol + NADP(+) +
CA   H(2)O.
CF   Heme-thiolate.
CC   -!- Can also produce 25-hydroxycholesterol.
CC   -!- In addition, it can further hydroxylate the product to 24,25-
CC       dihydroxycholesterol and 24,27-dihydroxycholesterol.
CC   -!- This reaction is the first step in the enzymatic degradation of
CC       cholesterol in the brain as hydroxycholesterol can pass the blood-
CC       brain barrier whereas cholesterol cannot.
PR   PROSITE; PDOC00081;
DR   Q9Y6A2, CP46A_HUMAN;  Q9WVK8, CP46A_MOUSE;
//
ID   1.14.13.99
DE   24-hydroxycholesterol 7-alpha-hydroxylase.
AN   24-hydroxycholesterol 7-alpha-monooxygenase.
CA   (24R)-cholest-5-ene-3-beta,24-diol + NADPH + O(2) = (24R)-cholest-5-ene-
CA   3-beta,7-alpha,24-triol + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- Found in liver microsomes and in ciliary non-pigmented epithelium.
CC   -!- Specific for (24R)-cholest-5-ene-3-beta,24-diol as substrate.
PR   PROSITE; PDOC00081;
DR   Q9NYL5, CP39A_HUMAN;  Q9JKJ9, CP39A_MOUSE;
//
ID   1.14.13.100
DE   25-hydroxycholesterol 7-alpha-hydroxylase.
AN   25-hydroxycholesterol 7-alpha-monooxygenase.
CA   (1) Cholest-5-ene-3-beta,25-diol + NADPH + O(2) = cholest-5-ene-3-beta,7-
CA   alpha,25-triol + NADP(+) + H(2)O.
CA   (2) Cholest-5-ene-3-beta,27-diol + NADPH + O(2) = cholest-5-ene-3-beta,7-
CA   alpha,27-triol + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- Unlike EC 1.14.13.99 which is specific for its oxysterol substrate,
CC       this enzyme can also metabolize the oxysterols 24,25-
CC       epoxycholesterol, 22-hydroxycholesterol and 24-hydroxycholesterol,
CC       but to a lesser extent.
PR   PROSITE; PDOC00081;
DR   O75881, CP7B1_HUMAN;  Q60991, CP7B1_MOUSE;  Q63688, CP7B1_RAT  ;
//
ID   1.14.13.101
DE   Senecionine N-oxygenase.
AN   Senecionine monooxygenase (N-oxide-forming).
CA   Senecionine + NADPH + O(2) = senecionine N-oxide + NADP(+) + H(2)O.
CC   -!- NADH cannot replace NADPH.
CC   -!- While pyrrolizidine alkaloids of the senecionine and monocrotaline
CC       types are generally good substrates (e.g. senecionine, retrorsine and
CC       monocrotaline), the enzyme does not use ester alkaloids lacking an
CC       hydroxy group at C-7 (e.g. supinine and phalaenopsine), 1,2-dihydro-
CC       alkaloids (e.g. sarracine) or unesterified necine bases (e.g.
CC       senkirkine) as substrates.
CC   -!- Senecionine N-oxide is used by insects as a chemical defense: it is
CC       non-toxic, but it is bioactivated to a toxic form by the action of
CC       cytochrome P-450 oxidase when absorbed by insectivores.
//
ID   1.14.13.102
DE   Psoralen synthase.
CA   (+)-marmesin + NADPH + O(2) = psoralen + NADP(+) + acetone + 2 H(2)O.
CC   -!- Specific for (+)-marmesin, and to a much lesser extent
CC       5-hydroxymarmesin, as substrate.
CC   -!- Furanocoumarins protect plants from fungal invasion and herbivore
CC       attack.
CC   -!- (+)-columbianetin, the angular furanocoumarin analog of the linear
CC       furanocoumarin (+)-marmesin, is not a substrate for the enzyme but it
CC       is a competitive inhibitor.
PR   PROSITE; PDOC00081;
DR   Q6QNI4, C71AJ_AMMMJ;  C0SJS4, C71AJ_APIGR;  C0SJS2, C71AJ_PASSA;
//
ID   1.14.13.103
DE   8-dimethylallylnaringenin 2'-hydroxylase.
AN   8-DMAN 2'-hydroxylase.
CA   Sophoraflavanone B + NADPH + O(2) = leachianone G + NADP(+) + H(2)O.
CC   -!- Specific for sophoraflavanone B as substrate.
CC   -!- NADPH cannot be replaced by NADH, FAD or FMN.
CC   -!- Along with EC 2.5.1.70 and EC 2.5.1.71, this enzyme forms part of the
CC       sophoraflavanone-G biosynthesis pathway.
//
ID   1.14.13.104
DE   (+)-menthofuran synthase.
AN   (+)-MFS.
AN   (+)-pulegone 9-hydroxylase.
AN   Menthofuran synthase.
CA   (+)-pulegone + NADPH + O(2) = (+)-menthofuran + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- The conversion of substrate into product involves the hydroxylation
CC       of the syn-methyl (C9), intramolecular cyclization to the hemiketal
CC       and dehydration to the furan.
CC   -!- This is the second cytochrome P-450-mediated step of monoterpene
CC       metabolism in peppermint, with the other step being catalyzed by
CC       EC 1.14.13.47.
PR   PROSITE; PDOC00081;
DR   Q947B7, MFS_MENPI  ;
//
ID   1.14.13.105
DE   Monocyclic monoterpene ketone monooxygenase.
AN   1-hydroxy-2-oxolimonene 1,2-monooxygenase.
AN   Dihydrocarvone 1,2-monooxygenase.
AN   MMKMO.
CA   (1) (-)-menthone + NADPH + O(2) = (4R,7S)-7-isopropyl-4-methyloxepan-2-
CA   one + NADP(+) + H(2)O.
CA   (2) Dihydrocarvone + NADPH + O(2) = 4-isopropenyl-7-methyloxepan-2-one +
CA   NADP(+) + H(2)O.
CA   (3) (Iso)-dihydrocarvone + NADPH + O(2) = 6-isopropenyl-3-methyloxepan-2-
CA   one + NADP(+) + H(2)O.
CA   (4) 1-hydroxymenth-8-en-2-one + NADPH + O(2) = 3-isopropenyl-6-
CA   oxoheptanoate + NADP(+) + H(2)O.
CF   FAD.
CC   -!- This Baeyer-Villiger monooxygenase enzyme from the Gram-positive
CC       bacterium Rhodococcus erythropolis DCL14 has wide substrate
CC       specificity, catalyzing the lactonization of a large number of
CC       monocyclic monoterpene ketones and substituted cyclohexanones.
CC   -!- Both (1R,4S)- and (1S,4R)-1-hydroxymenth-8-en-2-one are metabolized,
CC       with the lactone product spontaneously rearranging to form
CC       3-isopropenyl-6-oxoheptanoate.
DR   P82679, BVMO_RHOER ;
//
ID   1.14.13.106
DE   Epi-isozizaene 5-monooxygenase.
AN   CYP170A1.
CA   (1) (+)-epi-isozizaene + NADPH + O(2) = (5S)-albaflavenol + NADP(+) +
CA   H(2)O.
CA   (2) (5S)-albaflavenol + NADPH + O(2) = albaflavenone + NADP(+) + 2 H(2)O.
CA   (3) (+)-epi-isozizaene + NADPH + O(2) = (5R)-albaflavenol + NADP(+) +
CA   H(2)O.
CA   (4) (5R)-albaflavenol + NADPH + O(2) = albaflavenone + NADP(+) + 2 H(2)O.
CC   -!- This enzyme, from the soil-dwelling bacterium Streptomyces coelicolor
CC       A3(2), catalyzes two sequential allylic oxidation reactions.
CC   -!- The substrate epi-isozizaene, which is formed by the action of
CC       EC 4.2.3.37 is first oxidized to yield the epimeric intermediates
CC       (5R)-albaflavenol and (5S)-albaflavenol, which can be further
CC       oxidized to yield the sesquiterpenoid antibiotic albaflavenone.
//
ID   1.14.13.107
DE   Limonene 1,2-monooxygenase.
CA   (1) (S)-limonene + NAD(P)H + O(2) = 1,2-epoxymenth-8-ene + NAD(P)+
CA   + H(2)O.
CA   (2) (R)-limonene + NAD(P)H + O(2) = 1,2-epoxymenth-8-ene + NAD(P)+
CA   + H(2)O.
CF   FAD.
CC   -!- Limonene is the most widespread terpene and is formed by more than
CC       300 plants.
CC   -!- Rhodococcus erythropolis DCL14, a Gram-positive bacterium, is able to
CC       grow on both (S)-limonene and (R)-limonene as the sole source of
CC       carbon and energy.
CC   -!- NADPH can act instead of NADH, although more slowly.
CC   -!- It has not been established if the product formed is optically pure
CC       or a mixture of two enantiomers.
DR   Q9EUT9, LIMB_RHOER ;
//
ID   1.14.13.108
DE   Abietadiene hydroxylase.
AN   CYP720B1.
CA   Abietadiene + NADPH + O(2) = abietadienol + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- Catalyzes a step in the pathway of abietic acid biosynthesis.
CC   -!- The activity has been demonstrated in cell-free stem extracts of
CC       Abies grandis (grand fir) and Pinus contorta (lodgepole pine).
CC   -!- Activity is induced by wounding of the plant tissue.
//
ID   1.14.13.109
DE   Abietadienol hydroxylase.
AN   CYP720B1.
CA   Abietadienol + NADPH + O(2) = abietadienal + NADP(+) + 2 H(2)O.
CF   Heme-thiolate.
CC   -!- Catalyzes a step in the pathway of abietic acid biosynthesis.
CC   -!- The activity has been demonstrated in cell-free stem extracts of
CC       Abies grandis (grand fir) and Pinus contorta (lodgepole pine),
CC       and the gene encoding the enzyme has been identified in Pinus taeda
CC       (loblolly pine).
CC   -!- The recombinant enzyme catalyzed the oxidation of multiple diterpene
CC       alcohol and aldehydes, including levopimaradienol, isopimara-7,15-
CC       dienol, isopimara-7,15-dienal, dehydroabietadienol,
CC       and dehydroabietadienal.
CC   -!- It is not able to oxidize abietadiene.
PR   PROSITE; PDOC00081;
DR   Q50EK6, C72B1_PINTA;
//
ID   1.14.13.110
DE   Geranylgeraniol 18-hydroxylase.
AN   GGOH-18-hydroxylase.
CA   Geranylgeraniol + NADPH + O(2) = 18-hydroxygeranylgeraniol + NADP(+) +
CA   H(2)O.
CF   Heme-thiolate.
//
ID   1.14.13.111
DE   Methanesulfonate monooxygenase.
AN   Mesylate monooxygenase.
AN   Methanesulfonic acid monooxygenase.
AN   MSA monooxygenase.
AN   MSAMO.
CA   Methanesulfonate + NADH + O(2) = formaldehyde + NAD(+) + sulfite + H(2)O.
CF   Flavoprotein; Iron-sulfur.
CC   -!- Methanesulfonate is the simplest of the sulfonates and is a substrate
CC       for the growth of certain methylotrophic microorganisms.
CC   -!- Compared with EC 1.14.14.5, this enzyme has a restricted substrate
CC       range that includes only the short-chain aliphatic sulfonates
CC       (methane- to butanesulfonate) and excludes all larger molecules, such
CC       as arylsulfonates and aromatic sulfonates.
CC   -!- The enzyme from the bacterium Methylosulfonomonas methylovora is a
CC       multicomponent system comprising an hydroxylase, a reductase (MsmD;
CC       EC 1.5.1.29) and a ferredoxin (MsmC).
CC   -!- The hydroxylase has both large (MsmA) and small (MsmB) subunits, with
CC       each large subunit containing a Rieske-type [2Fe-2S] center.
CC   -!- Formerly EC 1.14.14.6.
//
ID   1.14.13.112
DE   3-epi-6-deoxocathasterone 23-monooxygenase.
AN   CYP90C1.
AN   CYP90D1.
CA   (1) 3-epi-6-deoxocathasterone + NADPH + O(2) = 6-deoxotyphasterol +
CA   NADP(+) + H(2)O.
CA   (2) (22S,24R)-22-hydroxy-5-alpha-ergostan-3-one + NADPH + O(2) =
CA   3-dehydro-6-deoxoteasterone + NADP(+) + H(2)O.
CC   -!- This enzyme is involved in brassinosteroid biosynthesis.
CC   -!- C-23 hydroxylation shortcuts bypass campestanol, 6-deoxocathasterone,
CC       and 6-deoxoteasterone and lead directly from (22S,24R)-22-hydroxy-5-
CC       alpha-ergostan-3-one and 3-epi-6-deoxocathasterone to 3-dehydro-6-
CC       deoxoteasterone and 6-deoxotyphasterol.
PR   PROSITE; PDOC00081;
DR   Q9M066, C90C1_ARATH;  Q94IA6, C90D1_ARATH;
//
ID   1.14.13.113
DE   FAD-dependent urate hydroxylase.
AN   FAD-dependent urate oxidase.
AN   Urate hydroxylase.
CA   Urate + NADH + O(2) = 5-hydroxyisourate + NAD(+) + H(2)O.
CF   Flavoprotein.
CC   -!- The reaction is part of the purine catabolic pathway in the bacterium
CC       Klebsiella pneumoniae.
CC   -!- The enzyme is different from EC 1.7.3.3, found in most plants, which
CC       produces hydrogen peroxide.
CC   -!- The product of the enzyme is a substrate for EC 3.5.2.17.
//
ID   1.14.13.114
DE   6-hydroxynicotinate 3-monooxygenase.
AN   6HNA monooxygenase.
AN   HNA-3-monooxygenase.
CA   6-hydroxynicotinate + NADH + O(2) = 2,5-dihydroxypyridine + NAD(+) +
CA   H(2)O + CO(2).
CF   FAD.
CC   -!- The reaction is involved in the aerobic catabolism of nicotinic acid.
DR   P86491, 6HN3M_PSEFL;
//
ID   1.14.13.115
DE   Angelicin synthase.
AN   CYP71AJ4.
CA   (+)-columbianetin + NADPH + O(2) = angelicin + NADP(+) + acetone +
CA   2 H(2)O.
CF   Heme-thiolate.
CC   -!- This P450 monooxygenase enzyme is involved in the formation of
CC       angular furanocoumarins.
CC   -!- Attacks its substrate by syn-elimination of hydrogen from C-3'.
DR   C0SJS3, ANGS_PASSA ;
//
ID   1.14.13.116
DE   Geranylhydroquinone 3''-hydroxylase.
AN   GHQ 3''-hydroxylase.
CA   Geranylhydroquinone + NADPH + O(2) = 3''-hydroxygeranylhydroquinone +
CA   NADP(+) + H(2)O.
CC   -!- Contains cytochrome P450.
//
ID   1.14.13.117
DE   Isoleucine N-monooxygenase.
CA   L-isoleucine + 2 H(+) + 2 NADPH + 2 O(2) = (E)-2-methylbutanal oxime +
CA   CO(2) + 3 H(2)O + 2 NADP(+).
CF   Heme-thiolate.
CC   -!- This enzyme catalyzes two successive N-hydroxylations of
CC       L-isoleucine, the first committed steps in the biosynthesis of the
CC       cyanogenic glucoside lotaustralin in the plant Lotus japonicus.
CC   -!- The product of the two hydroxylations, N,N-dihydroxy-L-isoleucine,
CC       is extremely labile and dehydrates spontaneously.
CC   -!- The dehydrated product is then subject to a decarboxylation that
CC       produces the oxime.
CC   -!- It is still not known whether the decarboxylation is spontaneous or
CC       catalyzed by the enzyme.
CC   -!- The product, (E)-2-methylbutanal oxime, undergoes a spontaneous
CC       isomerization to the (Z) form.
CC   -!- The enzyme can also accept L-valine as substrate, with a lower
CC       activity.
CC   -!- It is different from EC 1.14.13.118 which prefers L-valine.
DR   Q6J541, C79D3_LOTJA;  Q6J540, C79D4_LOTJA;
//
ID   1.14.13.118
DE   Valine N-monooxygenase.
CA   L-valine + 2 H(+) + 2 NADPH + 2 O(2) = (Z)-2-methylpropanal oxime + CO(2)
CA   + 3 H(2)O + 2 NADP(+).
CF   Heme-thiolate.
CC   -!- This enzyme catalyzes two successive N-hydroxylations of L-valine,
CC       the first committed steps in the biosynthesis of the cyanogenic
CC       glucoside linamarin in the plant Manihot esculenta (cassava).
CC   -!- The product of the two hydroxylations, N,N-dihydroxy-L-valine,
CC       is extremely labile and dehydrates spontaneously.
CC   -!- The dehydrated product is then subject to a decarboxylation that
CC       produces the oxime.
CC   -!- It is still not known whether the decarboxylation is spontaneous or
CC       catalyzed by the enzyme.
CC   -!- The product, (E)-2-methylpropanal oxime, undergoes a spontaneous
CC       isomerization to the (Z) form.
CC   -!- The enzyme can also accept L-isoleucine as substrate, with a lower
CC       activity.
CC   -!- It is different from EC 1.14.13.117 which prefers L-isoleucine.
DR   Q9M7B8, C79D1_MANES;  Q9M7B7, C79D2_MANES;
//
ID   1.14.13.119
DE   5-epiaristolochene 1,3-dihydroxylase.
AN   5-epi-aristolochene 1,3-dihydroxylase.
AN   CYP71D20.
AN   EAH.
CA   5-epiaristolochene + 2 NADPH + 2 O(2) = capsidiol + 2 NADP(+) + 2 H(2)O.
CF   Heme-thiolate.
CC   -!- Kinetic studies suggest that 1-beta-hydroxyepiaristolochene is mainly
CC       formed first followed by hydroxylation at C-3.
CC   -!- However the reverse order via 3-alpha-hydroxyepiaristolochene does
CC       occur.
PR   PROSITE; PDOC00081;
DR   Q94FM7, C71DK_TOBAC;
//
ID   1.14.13.120
DE   Costunolide synthase.
CA   Germacra-1(10),4,11(13)-trien-12-oate + NADPH + O(2) = (+)-costunolide +
CA   NADP(+) + 2 H(2)O.
CF   Heme-thiolate.
CC   -!- The enzyme hydroxylates carbon C-6 of germacra-1(10),4,11(13)-trien-
CC       12-oate to give 6-alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate,
CC       which probably spontaneously cyclises to form the lactone ring.
//
ID   1.14.13.121
DE   Premnaspirodiene oxygenase.
AN   HPO.
AN   Hyoscymus muticus premnaspirodiene oxygenase.
CA   (1) (-)-vetispiradiene + NADPH + O(2) = solavetivol + NADP(+) + H(2)O.
CA   (2) Solavetivol + NADPH + O(2) = solavetivone + NADP(+) + 2 H(2)O.
CF   Heme-thiolate.
CC   -!- The enzyme from the plant Hyoscymus muticus also hydroxylates
CC       valencene at C-2 to give the alpha-hydroxy compound, nootkatol,
CC       and this is converted into nootkatone.
CC   -!- 5-Epiaristolochene and epieremophilene are hydroxylated at C-2 to
CC       give a 2-beta-hydroxy derivative which is not further oxidized.
PR   PROSITE; PDOC00081;
DR   A6YIH8, C7D55_HYOMU;
//
ID   1.14.13.122
DE   Chlorophyllide-a oxygenase.
AN   CAO.
AN   Chlorophyllide a oxygenase.
AN   Cholorophyll-b synthase.
CA   Chlorophyllide a + 2 O(2) + 2 NADPH = chlorophyllide b + 3 H(2)O +
CA   2 NADP(+).
CF   Iron.
CC   -!- Catalyzes two successive hydroxylations at the 7-methyl group of
CC       chlorophyllide a.
CC   -!- The second step yields the aldehyde hydrate, which loses H(2)O
CC       spontaneously to form chlorophyllide b.
CC   -!- Chlorophyll a and protochlorophyllide a are not substrates.
CC   -!- Formerly EC 1.13.12.14.
DR   Q9MBA1, CAO_ARATH  ;  Q9ZWM5, CAO_CHLRE  ;  Q9XJ38, CAO_DUNSA  ;
DR   Q8S7E1, CAO_ORYSJ  ;
//
ID   1.14.13.123
DE   Germacrene A hydroxylase.
CA   (+)-germacrene A + NADPH + O(2) = germacra-1(10),4,11(13)-trien-12-ol +
CA   NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- This is probably part of the biosynthesis of many sesquiterpenoid
CC       lactones.
CC   -!- In Lactuca sativa EC 1.14.13.213 is a mutifunctional enzyme with
CC       EC 1.1.1.314.
DR   D5JBX1, GAO_BARSP  ;  D5JBW8, GAO_CICIN  ;  D5JBX0, GAO_HELAN  ;
DR   D5J9U8, GAO_LACSA  ;  D5JBW9, GAO_SAUCO  ;
//
ID   1.14.13.124
DE   Phenylalanine N-monooxygenase.
AN   CYP79A2.
AN   Phenylalanine N-hydroxylase.
CA   L-phenylalanine + 2 NADPH + 2 O(2) = (E)-phenylacetaldoxime + 2 NADP(+) +
CA   3 H(2)O + CO(2).
CF   Heme-thiolate.
CC   -!- This enzyme catalyzes two successive N-hydroxylations of
CC       L-phenylalanine, the first committed steps in the biosynthesis of
CC       benzylglucosinolate.
CC   -!- The product of the two hydroxylations, N,N-dihydroxy-L-phenylalanine,
CC       is extremely labile and dehydrates spontaneously.
CC   -!- The dehydrated product is then subject to a decarboxylation that
CC       produces the oxime.
CC   -!- It is still not known whether the decarboxylation is spontaneous or
CC       catalyzed by the enzyme.
CC   -!- The product, (E)-phenylacetaldoxime, undergoes a spontaneous
CC       isomerization to the (Z) form.
CC   -!- Formerly EC 1.14.13.n1.
DR   Q9FLC8, C79A2_ARATH;
//
ID   1.14.13.125
DE   Tryptophan N-monooxygenase.
AN   CYP79B1.
AN   CYP79B2.
AN   CYP79B3.
AN   Tryptophan N-hydroxylase.
CA   L-tryptophan + 2 NADPH + 2 O(2) = indole-3-acetaldoxime + 2 NADP(+) +
CA   3 H(2)O + CO(2).
CF   Heme-thiolate.
CC   -!- This enzyme catalyzes two successive N-hydroxylations of
CC       L-tryptophan, the first steps in the biosynthesis of the both auxin
CC       and the indole alkaloid phytoalexin camalexin.
CC   -!- The product of the two hydroxylations, N,N-dihydroxy-L-tryptophan,
CC       is extremely labile and dehydrates spontaneously.
CC   -!- The dehydrated product is then subject to a decarboxylation that
CC       produces the oxime.
CC   -!- It is still not known whether the decarboxylation is spontaneous or
CC       catalyzed by the enzyme.
CC   -!- The product, (E)-indol-3-ylacetaldoxime, undergoes a spontaneous
CC       isomerization to the (Z) form.
CC   -!- Formerly EC 1.14.13.n2.
DR   O81346, C79B2_ARATH;  Q501D8, C79B3_ARATH;
//
ID   1.14.13.126
DE   Vitamin D(3) 24-hydroxylase.
AN   CYP24A1.
CA   (1) Calcitriol + NADPH + O(2) = calcitetrol + NADP(+) + H(2)O.
CA   (2) Calcidiol + NADPH + O(2) = secalciferol + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- The second donor, NADPH, donates electrons through EC 1.18.1.2 and a
CC       [2Fe-2S] ferredoxin.
CC   -!- The enzyme can perform up to 6 rounds of hydroxylation of the
CC       substrate calcitriol leading to calcitroic acid.
CC   -!- The human enzyme also shows 23-hydroxylating activity leading to
CC       1-alpha,25 dihydroxyvitamin D(3)-26,23-lactone as end product while
CC       the mouse and rat enzymes do not.
CC   -!- Formerly EC 1.14.13.n4.
DR   Q07973, CP24A_HUMAN;  Q64441, CP24A_MOUSE;  Q09128, CP24A_RAT  ;
//
ID   1.14.13.127
DE   3-(3-hydroxy-phenyl)propanoic acid hydroxylase.
CA   (1) 3-(3-hydroxyphenyl)propanoate + NADH + O(2) = 3-(2,3-
CA   dihydroxyphenyl)propanoate + H(2)O + NAD(+).
CA   (2) (2E)-3-(3-hydroxyphenyl)prop-2-enoate + NADH + O(2) = (2E)-3-(2,3-
CA   dihydroxyphenyl)prop-2-enoate + H(2)O + NAD(+).
CF   FAD.
CC   -!- This enzyme participates in a meta-cleavage pathway employed by the
CC       bacterium Escherichia coli for the degradation of various
CC       phenylpropanoid compounds.
CC   -!- Formerly EC 1.14.13.n3.
DR   A4JPY1, MHPA1_BURVG;  A4JQH4, MHPA2_BURVG;  Q1BGA7, MHPA_BURCA ;
DR   A0KE38, MHPA_BURCH ;  Q13QI0, MHPA_BURXL ;  Q9S158, MHPA_COMTE ;
DR   Q476N1, MHPA_CUPPJ ;  A7ZI94, MHPA_ECO24 ;  B7L503, MHPA_ECO55 ;
DR   Q8X680, MHPA_ECO57 ;  B5Z2Q2, MHPA_ECO5E ;  B7NK08, MHPA_ECO7I ;
DR   B7MPB4, MHPA_ECO81 ;  B7M2Z5, MHPA_ECO8A ;  B1XBJ4, MHPA_ECODH ;
DR   A7ZWZ4, MHPA_ECOHS ;  P77397, MHPA_ECOLI ;  B7N8Q4, MHPA_ECOLU ;
DR   B6HZX3, MHPA_ECOSE ;  B1LIN2, MHPA_ECOSM ;  B5XQI9, MHPA_KLEP3 ;
DR   A6TAC9, MHPA_KLEP7 ;  A0QB57, MHPA_MYCA1 ;  A4T8B6, MHPA_MYCGI ;
DR   Q742Z1, MHPA_MYCPA ;  A0R1T4, MHPA_MYCS2 ;  A3Q339, MHPA_MYCSJ ;
DR   A1UJP4, MHPA_MYCSK ;  Q1B5E2, MHPA_MYCSS ;  A1TCX2, MHPA_MYCVP ;
DR   Q3Z585, MHPA_SHISS ;
//
ID   1.14.13.128
DE   7-methylxanthine demethylase.
CA   7-methylxanthine + O(2) + NAD(P)H = xanthine + NAD(P)(+) + H(2)O +
CA   formaldehyde.
CF   Iron.
CC   -!- NADH is the preferred cofactor.
CC   -!- Part of the caffeine degradation pathway in Pseudomonas putida.
CC   -!- Also demethylates 1,7-dimethylxanthine (paraxanthine), theobromine,
CC       3-methylxanthine, and caffeine with lower efficiency.
//
ID   1.14.13.129
DE   Beta-carotene 3-hydroxylase.
AN   Beta-carotene 3,3'-monooxygenase.
CA   Beta-carotene + 2 NADH + 2 O(2) = zeaxanthin + 2 NAD(+) + 2 H(2)O.
CF   Iron.
CC   -!- Also acts on other carotenoids with a beta-end group.
CC   -!- In some species canthaxanthin is the preferred substrate.
DR   Q9SZZ8, BCH1_ARATH ;  O49815, BCH1_CAPAN ;  Q9LTG0, BCH2_ARATH ;
DR   O49814, BCH2_CAPAN ;  B3SGL0, BCH_GENLU  ;  Q9SPK6, BCH_HAEPL  ;
//
ID   1.14.13.130
DE   Pyrrole-2-carboxylate monooxygenase.
AN   Pyrrole-2-carboxylate ooxygenase.
CA   Pyrrole-2-carboxylate + NADH + O(2) = 5-hydroxypyrrole-2-carboxylate +
CA   NAD(+) + H(2)O.
CF   FAD.
CC   -!- The enzyme initiates the degradation of pyrrole-2-carboxylate.
//
ID   1.14.13.n1
DE   Transferred entry: 1.14.13.124.
//
ID   1.14.13.n2
DE   Transferred entry: 1.14.13.125.
//
ID   1.14.13.n3
DE   Transferred entry: 1.14.13.127.
//
ID   1.14.13.n4
DE   Transferred entry: 1.14.13.126.
//
ID   1.14.13.n5
DE   Dihomomethionine N-hydroxylase.
AN   CYP79F1.
CA   (1) Dihomomethionine + 2 O(2) + 2 NADPH = 5-methylthiopentanaldoxime +
CA   3 H(2)O + CO(2) + 2 NADP(+).
CA   (2) Trihomomethionine + 2 O(2) + 2 NADPH = 6-methylthiohexanaldoxime +
CA   3 H(2)O + CO(2) + 2 NADP(+).
CF   Heme-thiolate.
CC   -!- The enzyme also catalyzes the N-hydroxylation of longer chain
CC       elongated methionines up to hexahomomethionine.
DR   Q949U1, C79F1_ARATH;
//
ID   1.14.13.n6
DE   Hexahomomethionine N-hydroxylase.
CA   (1) Hexahomomethionine + 2 O(2) + 2 NADPH = 9-methylthiononanaldoxime +
CA   3 H(2)O + CO(2) + NADP(+).
CA   (2) Pentahomomethionine + 2 O(2) + 2 NADPH = 8-methylthiooctanaldoxime +
CA   3 H(2)O + CO(2) + NADP(+).
CF   Heme-thiolate.
DR   Q9FUY7, C79F2_ARATH;
//
ID   1.14.13.n7
DE   4-nitrophenol 2-hydroxylase.
AN   CYP2E1.
CA   4-nitrophenol + NADPH + O(2) = 4-nitrocatechol + NADP(+) + H(2)O.
CF   Heme-thiolate.
DR   O18963, CP2E1_BOVIN;  Q9MZY0, CP2E1_CANFA;  P05181, CP2E1_HUMAN;
DR   P33266, CP2E1_MACFA;  Q6GUQ4, CP2E1_MACMU;  P51581, CP2E1_MESAU;
DR   Q05421, CP2E1_MOUSE;  P79383, CP2E1_PIG  ;  P08682, CP2E1_RABIT;
DR   P05182, CP2E1_RAT  ;
//
ID   1.14.14.1
DE   Unspecific monooxygenase.
AN   Aryl hydrocarbon hydroxylase.
AN   Aryl-4-monooxygenase.
AN   Cytochrome p450.
AN   Flavoprotein-linked monooxygenase.
AN   Microsomal monooxygenase.
AN   Microsomal p450.
AN   Xenobiotic monooxygenase.
CA   RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.
CF   Heme-thiolate.
CC   -!- Acts on a wide range of substrates including many xenobiotics,
CC       steroids, fatty acids, vitamins and prostaglandins.
CC   -!- Reactions catalyzed include hydroxylation, epoxidation, N-oxidation,
CC       sulfooxidation, N-, S- and O-dealkylations, desulfation, deamination,
CC       and reduction of azo, nitro, and N-oxide groups.
CC   -!- Formerly EC 1.14.1.1, EC 1.14.14.2, EC 1.14.99.8 and EC 1.99.1.1.
PR   PROSITE; PDOC00081;
DR   O42145, C19AA_DANRE;  Q9PVE8, C330_FUNHE ;  Q98T91, C340_ORYLA ;
DR   Q8AXY5, C356_FUNHE ;  Q9Y8G7, C505_FUSOX ;  P79690, CP191_CARAU;
DR   Q29624, CP191_PIG  ;  O73686, CP192_CARAU;  P79430, CP192_PIG  ;
DR   P79304, CP193_PIG  ;  Q6QHT9, CP19A_ANGJA;  P46194, CP19A_BOVIN;
DR   Q95M61, CP19A_CALJA;  Q5QQX7, CP19A_CANFA;  Q6YI21, CP19A_CAPHI;
DR   P19098, CP19A_CHICK;  P79699, CP19A_COTJA;  O46512, CP19A_HORSE;
DR   P11511, CP19A_HUMAN;  Q92111, CP19A_ICTPU;  Q69FB6, CP19A_LAGAC;
DR   P28649, CP19A_MOUSE;  P70091, CP19A_ORENI;  Q92087, CP19A_ORYLA;
DR   Q29605, CP19A_RABIT;  P22443, CP19A_RAT  ;  Q9XS28, CP19A_SHEEP;
DR   Q92112, CP19A_TAEGU;  Q3LFU0, CP1A1_BALAC;  P56590, CP1A1_CANFA;
DR   Q06367, CP1A1_CAVPO;  Q92039, CP1A1_CHACA;  P79716, CP1A1_DICLA;
DR   Q5KQT7, CP1A1_FELCA;  P04798, CP1A1_HUMAN;  O42430, CP1A1_LIMLI;
DR   O42231, CP1A1_LIZAU;  Q9W683, CP1A1_LIZSA;  P33616, CP1A1_MACFA;
DR   Q6GUR1, CP1A1_MACMU;  Q00557, CP1A1_MESAU;  Q92148, CP1A1_MICTO;
DR   P00184, CP1A1_MOUSE;  Q92110, CP1A1_ONCMY;  Q92095, CP1A1_OPSTA;
DR   Q6JZS3, CP1A1_ORYLA;  P98181, CP1A1_PAGMA;  Q9YH64, CP1A1_PLAFE;
DR   Q92100, CP1A1_PLEPL;  P05176, CP1A1_RABIT;  P00185, CP1A1_RAT  ;
DR   P56591, CP1A1_SHEEP;  O42457, CP1A1_SPAAU;  Q92116, CP1A1_STECH;
DR   Q3LFT9, CP1A2_BALAC;  O77810, CP1A2_CALJA;  P56592, CP1A2_CANFA;
DR   Q64391, CP1A2_CAVPO;  Q01741, CP1A2_CHICK;  Q5KQT6, CP1A2_FELCA;
DR   P05177, CP1A2_HUMAN;  O77809, CP1A2_MACFA;  Q4H4C3, CP1A2_MACFU;
DR   P24453, CP1A2_MESAU;  P00186, CP1A2_MOUSE;  Q5RBQ1, CP1A2_PONAB;
DR   P00187, CP1A2_RABIT;  P04799, CP1A2_RAT  ;  Q92109, CP1A3_ONCMY;
DR   P79760, CP1A4_CHICK;  P79761, CP1A5_CHICK;  Q16678, CP1B1_HUMAN;
DR   Q64429, CP1B1_MOUSE;  Q64678, CP1B1_RAT  ;  P56654, CP237_MOUSE;
DR   P56655, CP238_MOUSE;  P56656, CP239_MOUSE;  P56657, CP240_MOUSE;
DR   O62671, CP241_CANFA;  P79402, CP242_PIG  ;  Q6XVG2, CP254_MOUSE;
DR   Q9D816, CP255_MOUSE;  P33273, CP255_RAT  ;  Q91W64, CP270_MOUSE;
DR   P19225, CP270_RAT  ;  P11711, CP2A1_RAT  ;  P15149, CP2A2_RAT  ;
DR   P20812, CP2A3_RAT  ;  P15392, CP2A4_MOUSE;  P20852, CP2A5_MOUSE;
DR   P11509, CP2A6_HUMAN;  P20853, CP2A7_HUMAN;  P80055, CP2A7_PAPSP;
DR   P24454, CP2A8_MESAU;  P24455, CP2A9_MESAU;  Q05555, CP2AA_RABIT;
DR   Q05556, CP2AB_RABIT;  P56593, CP2AC_MOUSE;  Q16696, CP2AD_HUMAN;
DR   P22779, CP2AX_BOVIN;  P00176, CP2B1_RAT  ;  P04167, CP2B2_RAT  ;
DR   P13107, CP2B3_RAT  ;  P00178, CP2B4_RABIT;  P12789, CP2B5_RABIT;
DR   P20813, CP2B6_HUMAN;  P12790, CP2B9_MOUSE;  P12791, CP2BA_MOUSE;
DR   P24460, CP2BB_CANFA;  P33272, CP2BC_RAT  ;  Q64583, CP2BF_RAT  ;
DR   O55071, CP2BJ_MOUSE;  P34033, CP2BX_CAVPO;  P00180, CP2C1_RABIT;
DR   P00181, CP2C2_RABIT;  P00182, CP2C3_RABIT;  P11371, CP2C4_RABIT;
DR   P00179, CP2C5_RABIT;  P05178, CP2C6_RAT  ;  P05179, CP2C7_RAT  ;
DR   P10632, CP2C8_HUMAN;  P08683, CP2CB_RAT  ;  P11510, CP2CC_RAT  ;
DR   P20814, CP2CD_RAT  ;  P17666, CP2CE_RABIT;  P11372, CP2CF_RABIT;
DR   P15123, CP2CG_RABIT;  P33260, CP2CI_HUMAN;  P33262, CP2CK_MACFA;
DR   P56594, CP2CL_CANFA;  P24470, CP2CN_RAT  ;  Q08078, CP2CP_MESAU;
DR   P33263, CP2CQ_MESAU;  P33264, CP2CR_MESAU;  P33265, CP2CS_MESAU;
DR   Q64458, CP2CT_MOUSE;  Q29510, CP2CU_RABIT;  Q29478, CP2CV_CAPAE;
DR   P10633, CP2D1_RAT  ;  P12938, CP2D3_RAT  ;  P13108, CP2D4_RAT  ;
DR   P10635, CP2D6_HUMAN;  Q2XNC9, CP2D6_PANPA;  Q2XNC8, CP2D6_PANTR;
DR   P11714, CP2D9_MOUSE;  P24456, CP2DA_MOUSE;  P12939, CP2DA_RAT  ;
DR   P24457, CP2DB_MOUSE;  Q01361, CP2DE_BOVIN;  Q29473, CP2DF_CANFA;
DR   Q64403, CP2DG_CAVPO;  Q29488, CP2DH_MACFA;  Q64680, CP2DI_RAT  ;
DR   O18992, CP2DJ_CALJA;  Q8CIM7, CP2DQ_MOUSE;  P10634, CP2DQ_RAT  ;
DR   P24903, CP2F1_HUMAN;  O18809, CP2F3_CAPHI;  Q8WNE1, CP2F5_GORGO;
DR   P24461, CP2G1_RABIT;  P10610, CP2G1_RAT  ;  P05180, CP2H1_CHICK;
DR   P20678, CP2H2_CHICK;  P52786, CP2J1_RABIT;  P51589, CP2J2_HUMAN;
DR   P51590, CP2J3_RAT  ;  O54749, CP2J5_MOUSE;  O54750, CP2J6_MOUSE;
DR   Q92090, CP2K1_ONCMY;  O93299, CP2K3_ONCMY;  O93297, CP2K4_ONCMY;
DR   Q27712, CP2L1_PANAR;  Q92088, CP2M1_ONCMY;  Q96SQ9, CP2S1_HUMAN;
DR   Q9DBX6, CP2S1_MOUSE;  Q0IIF9, CP2U1_BOVIN;  Q7Z449, CP2U1_HUMAN;
DR   Q9CX98, CP2U1_MOUSE;  Q4V8D1, CP2U1_RAT  ;  Q9JMA7, CP341_MOUSE;
DR   Q9HB55, CP343_HUMAN;  P04800, CP3A1_RAT  ;  P05183, CP3A2_RAT  ;
DR   P20815, CP3A5_HUMAN;  P80056, CP3A5_PAPSP;  P11707, CP3A6_RABIT;
DR   P24462, CP3A7_HUMAN;  P33268, CP3A8_MACFA;  P51538, CP3A9_RAT  ;
DR   Q64459, CP3AB_MOUSE;  P24463, CP3AC_CANFA;  Q64464, CP3AD_MOUSE;
DR   Q64417, CP3AE_CAVPO;  Q64406, CP3AF_CAVPO;  Q64481, CP3AG_MOUSE;
DR   Q64409, CP3AH_CAVPO;  Q64581, CP3AI_RAT  ;  P79152, CP3AJ_CAPAE;
DR   O18993, CP3AL_CALJA;  Q29496, CP3AO_SHEEP;  O09158, CP3AP_MOUSE;
DR   O42563, CP3AR_ONCMY;  P79102, CP3AS_BOVIN;  P79401, CP3AT_PIG  ;
DR   O70537, CP3AV_MESAU;  P10611, CP4A4_RABIT;  P24464, CP4AC_RAT  ;
DR   P13584, CP4B1_HUMAN;  Q64462, CP4B1_MOUSE;  P15128, CP4B1_RABIT;
DR   P15129, CP4B1_RAT  ;  P29981, CP4C1_BLADI;  Q91WL5, CP4CA_MOUSE;
DR   Q964T1, CP4CU_BLAGE;  P33274, CP4F1_RAT  ;  P51869, CP4F4_RAT  ;
DR   P51870, CP4F5_RAT  ;  P51871, CP4F6_RAT  ;  P98187, CP4F8_HUMAN;
DR   Q9HBI6, CP4FB_HUMAN;  Q9HCS2, CP4FC_HUMAN;  Q8N118, CP4X1_HUMAN;
DR   Q8K4D6, CP4X1_RAT  ;  Q86W10, CP4Z1_HUMAN;  P13527, CP6A1_MUSDO;
DR   Q04552, CP6B1_PAPPO;  Q27664, CP6B2_HELAM;  Q27756, CP6B3_PAPPO;
DR   Q27902, CP6B4_PAPGL;  Q95036, CP6B5_PAPGL;  Q95031, CP6B6_HELAM;
DR   O61387, CP6B7_HELAM;  P14779, CPXB_BACME ;  Q91X77, CY250_MOUSE;
DR   O08394, CYPD_BACSU ;  O08336, CYPE_BACSU ;
//
ID   1.14.14.2
DE   Transferred entry: 1.14.14.1.
//
ID   1.14.14.3
DE   Alkanal monooxygenase (FMN-linked).
AN   Aldehyde monooxygenase.
AN   Bacterial luciferase.
CA   RCHO + reduced FMN + O(2) = RCOOH + FMN + H(2)O + light.
CC   -!- The reaction involves incorporation of a molecule of oxygen into
CC       reduced FMN, and subsequent reaction with the aldehyde to form an
CC       activated FMN.H(2)O complex which breaks down with emission of light.
CC   -!- The enzyme is highly specific for reduced FMN, and for long-chain
CC       aliphatic aldehydes with 8 carbons or more.
PR   PROSITE; PDOC00397;
DR   P09140, LUXA1_PHOLE;  P19839, LUXA1_PHOLU;  P29238, LUXA2_PHOLE;
DR   P23146, LUXA2_PHOLU;  P18299, LUXA_KRYAS ;  Q7N575, LUXA_PHOLL ;
DR   P24113, LUXA_PHOPO ;  P24114, LUXA_VIBAB ;  P19907, LUXA_VIBFI ;
DR   P07740, LUXA_VIBHA ;  P09141, LUXB1_PHOLE;  P19840, LUXB1_PHOLU;
DR   P29239, LUXB2_PHOLE;  P23147, LUXB2_PHOLU;  P18300, LUXB_KRYAS ;
DR   Q7N574, LUXB_PHOLL ;  P12744, LUXB_PHOPO ;  P19908, LUXB_VIBFI ;
DR   P07739, LUXB_VIBHA ;
//
ID   1.14.14.4
DE   Transferred entry: 1.14.15.7.
//
ID   1.14.14.5
DE   Alkanesulfonate monooxygenase.
AN   FMNH(2)-dependent aliphatic sulfonate monooxygenase.
AN   Sulfate starvation-induced protein 6.
CA   An alkanesufonate (R-CH(2)-SO(3)H) + FMNH(2) + O(2) = an aldehyde (R-CHO)
CA   + FMN + sulfite + H(2)O.
CC   -!- The enzyme from Escherichia coli catalyzes the desulfonation of a
CC       wide range of aliphatic sulfonates (unsubstituted C(1)- to C(14)-
CC       sulfonates as well as substituted C(2)-sulfonates).
CC   -!- Does not desulfonate taurine (2-aminoethanesulfonate) or aromatic
CC       sulfonates.
CC   -!- Does not use FMN as a bound cofactor.
CC   -!- Instead, it uses reduced FMN (i.e., FMNH(2)) as a substrate.
CC   -!- FMNH(2) is provided by SsuE, the associated FMN reductase
CC       (EC 1.5.1.29).
DR   Q9I1C2, MSUD_PSEAE ;  Q98CB9, SSUD1_RHILO;  Q98DT4, SSUD2_RHILO;
DR   A1TRM3, SSUD_ACIAC ;  Q8UAE8, SSUD_AGRT5 ;  C1DN48, SSUD_AZOVD ;
DR   A7Z2Q3, SSUD_BACA2 ;  Q65M61, SSUD_BACLD ;  P40402, SSUD_BACSU ;
DR   Q89ER2, SSUD_BRAJA ;  Q3JSR8, SSUD_BURP1 ;  B2JKA8, SSUD_BURP8 ;
DR   B2T3J1, SSUD_BURPP ;  Q2SVM8, SSUD_BURTA ;  Q9KHR3, SSUD_BUTSP ;
DR   A8AID7, SSUD_CITK8 ;  Q0K9I0, SSUD_CUPNH ;  Q46ZU3, SSUD_CUPPJ ;
DR   B3R2K7, SSUD_CUPTR ;  A9C3F6, SSUD_DELAS ;  A7ZK27, SSUD_ECO24 ;
DR   B7UN21, SSUD_ECO27 ;  B7MHP4, SSUD_ECO45 ;  B7LE35, SSUD_ECO55 ;
DR   Q8XDD9, SSUD_ECO57 ;  B5YT69, SSUD_ECO5E ;  B7NM39, SSUD_ECO7I ;
DR   B7MS53, SSUD_ECO81 ;  B7M864, SSUD_ECO8A ;  C4ZQ61, SSUD_ECOBW ;
DR   B1X8N9, SSUD_ECODH ;  A7ZYN8, SSUD_ECOHS ;  A1A9L2, SSUD_ECOK1 ;
DR   Q0TJB9, SSUD_ECOL5 ;  Q8FJ93, SSUD_ECOL6 ;  B1IVZ6, SSUD_ECOLC ;
DR   P80645, SSUD_ECOLI ;  B7N3A4, SSUD_ECOLU ;  B6I909, SSUD_ECOSE ;
DR   B1LJS7, SSUD_ECOSM ;  Q1RDS2, SSUD_ECOUT ;  A4W8V4, SSUD_ENT38 ;
DR   A7MEW3, SSUD_ENTS8 ;  Q6CYU4, SSUD_ERWCT ;  D2TDP0, SSUD_ERWP6 ;
DR   B2VC88, SSUD_ERWT9 ;  B7LNV2, SSUD_ESCF3 ;  B7KX11, SSUD_METC4 ;
DR   C6DGK1, SSUD_PECCP ;  A1VPZ7, SSUD_POLNA ;  Q48H03, SSUD_PSE14 ;
DR   Q9HYG2, SSUD_PSEAE ;  Q1IGL6, SSUD_PSEE4 ;  A4Y0F3, SSUD_PSEMY ;
DR   A5VX17, SSUD_PSEP1 ;  B0KH56, SSUD_PSEPG ;  Q88R95, SSUD_PSEPK ;
DR   O85764, SSUD_PSEPU ;  B1JEV9, SSUD_PSEPW ;  Q87ZG3, SSUD_PSESM ;
DR   Q9KHS2, SSUD_PSESP ;  Q4ZRE3, SSUD_PSEU2 ;  Q1LNM2, SSUD_RALME ;
DR   B2UAU3, SSUD_RALPJ ;  Q8XZQ6, SSUD_RALSO ;  B3Q1C3, SSUD_RHIE6 ;
DR   Q6N6K3, SSUD_RHOPA ;  B3QIN8, SSUD_RHOPT ;  A8GCK1, SSUD_SERP5 ;
DR   Q0T6A4, SSUD_SHIF8 ;  P59189, SSUD_SHIFL ;  A9FK50, SSUD_SORC5 ;
DR   C5CNW9, SSUD_VARPS ;  Q8PP38, SSUD_XANAC ;  A7FDL9, SSUD_YERP3 ;
DR   Q1C1S2, SSUD_YERPA ;  B2K4U5, SSUD_YERPB ;  Q8ZB04, SSUD_YERPE ;
DR   Q1CDQ8, SSUD_YERPN ;  A4TH89, SSUD_YERPP ;  Q665B4, SSUD_YERPS ;
DR   B1JKC0, SSUD_YERPY ;
//
ID   1.14.14.6
DE   Transferred entry: 1.14.13.111.
//
ID   1.14.14.7
DE   Tryptophan 7-halogenase.
CA   Tryptophan + FADH(2) + Cl(-) + O(2) + H(+) = 7-chloro-L-tryptophan +
CA   FAD + 2 H(2)O.
CC   -!- In Lechevalieria aerocolonigenes the enzyme catalyzes the initial
CC       step in the biosynthesis of rebeccamycin.
//
ID   1.14.14.8
DE   Anthranilate 3-monooxygenase (FAD).
AN   Anthranilate 3-hydroxylase.
AN   Anthranilate hydroxylase.
CA   Anthranilate + FADH(2) + O(2) = 3-hydroxyanthranilate + FAD + H(2)O.
CC   -!- This enzyme, isolated from the bacterium Geobacillus
CC       thermodenitrificans, participates in the pathway of tryptophan
CC       degradation.
CC   -!- The enzyme is part of a system that also includes a bifunctional
CC       riboflavin kinase/FMN adenylyltransferase and an FAD reductase, which
CC       ensures ample supply of FAD to the monooxygenase.
//
ID   1.14.15.1
DE   Camphor 5-monooxygenase.
AN   Camphor 5-exo-methylene hydroxylase.
AN   Cytochrome p450-cam.
CA   (+)-camphor + putidaredoxin + O(2) = (+)-exo-5-hydroxycamphor + oxidized
CA   putidaredoxin + H(2)O.
CF   Heme-thiolate.
CC   -!- Also acts on (-)-camphor and 1,2-campholide, forming 5-exo-hydroxy-
CC       1,2-campholide.
PR   PROSITE; PDOC00081;
DR   P00183, CPXA_PSEPU ;
//
ID   1.14.15.2
DE   Camphor 1,2-monooxygenase.
AN   2,5-diketocamphane lactonizing enzyme.
AN   Camphor ketolactonase I.
CA   (+)-bornane-2,5-dione + reduced rubredoxin + O(2) = 5-oxo-1,2-campholide
CA   + oxidized rubredoxin + H(2)O.
CF   Iron.
//
ID   1.14.15.3
DE   Alkane 1-monooxygenase.
AN   Alkane 1-hydroxylase.
AN   Fatty acid omega-hydroxylase.
AN   Lauric acid omega-hydroxylase.
AN   Omega-hydroxylase.
CA   Octane + reduced rubredoxin + O(2) = 1-octanol + oxidized rubredoxin +
CA   H(2)O.
CC   -!- Some enzyme of this group are heme-thiolated proteins (P450).
CC   -!- Also hydroxylates fatty acids in the omega-position.
PR   PROSITE; PDOC00081;
DR   Q0VKZ3, ALKB1_ALCBS;  Q9I0R2, ALKB1_PSEAE;  Q0VTH3, ALKB2_ALCBS;
DR   Q6H941, ALKB2_PSEAE;  O31250, ALKB_ACIAD ;  P12691, ALKB_PSEOL ;
DR   Q9WWW6, ALKB_PSEPU ;  P20816, CP4A2_RAT  ;  P14579, CP4A5_RABIT;
DR   P14580, CP4A6_RABIT;  P14581, CP4A7_RABIT;  O88833, CP4AA_MOUSE;
DR   P08516, CP4AA_RAT  ;  Q02928, CP4AB_HUMAN;  O35728, CP4AE_MOUSE;
DR   P20817, CP4AE_RAT  ;  Q5TCH4, CP4AM_HUMAN;  Q8SPK1, CP4AO_PIG  ;
DR   Q8SPK0, CP4AP_PIG  ;
//
ID   1.14.15.4
DE   Steroid 11-beta-monooxygenase.
AN   Cytochrome p450 XIB1.
AN   Steroid 11-beta-hydroxylase.
AN   Steroid 11-beta/18-hydroxylase.
CA   A steroid + reduced adrenal ferredoxin + O(2) = an 11-beta-hydroxysteroid
CA   + oxidized adrenal ferredoxin + H(2)O.
CF   Heme-thiolate.
CC   -!- Also hydroxylates steroids at the 18-position, and converts
CC       18-hydroxycorticosterone into aldosterone.
CC   -!- Formerly EC 1.14.1.6 and EC 1.99.1.7.
PR   PROSITE; PDOC00081;
DR   P15150, C11B1_BOVIN;  Q64408, C11B1_CAVPO;  P15538, C11B1_HUMAN;
DR   P97720, C11B1_MESAU;  Q29527, C11B1_PAPHU;  Q29552, C11B1_PIG  ;
DR   P15393, C11B1_RAT  ;  P51663, C11B1_SHEEP;  P19099, C11B2_HUMAN;
DR   Q64658, C11B2_MESAU;  P15539, C11B2_MOUSE;  P30099, C11B2_RAT  ;
DR   P30100, C11B3_RAT  ;  Q92104, CP11B_RANCA;
//
ID   1.14.15.5
DE   Corticosterone 18-monooxygenase.
AN   Corticosterone 18-hydroxylase.
AN   Corticosterone methyl oxidase.
CA   Corticosterone + reduced adrenal ferredoxin + O(2) =
CA   18-hydroxycorticosterone + oxidized adrenal ferredoxin + H(2)O.
CF   Heme-thiolate.
PR   PROSITE; PDOC00081;
DR   P19099, C11B2_HUMAN;  Q64658, C11B2_MESAU;  P15539, C11B2_MOUSE;
DR   P30099, C11B2_RAT  ;  P30100, C11B3_RAT  ;
//
ID   1.14.15.6
DE   Cholesterol monooxygenase (side-chain-cleaving).
AN   Cholesterol 20-22-desmolase.
AN   Cholesterol C(20-22) desmolase.
AN   Cholesterol desmolase.
AN   Cholesterol side-chain cleavage enzyme.
AN   Cholesterol side-chain-cleaving enzyme.
AN   Cytochrome P-450(scc).
AN   Cytochrome p450(scc).
AN   Steroid 20-22 desmolase.
AN   Steroid 20-22-lyase.
CA   Cholesterol + reduced adrenal ferredoxin + O(2) = pregnenolone +
CA   4-methylpentanal + oxidized adrenal ferredoxin + H(2)O.
CF   Heme-thiolate.
CC   -!- The reaction proceeds in three stages, with hydroxylation at C-20 and
CC       C-22 preceding scission of the side-chain at C-20.
PR   PROSITE; PDOC00081;
DR   P00189, CP11A_BOVIN;  P79153, CP11A_CAPHI;  Q92045, CP11A_DASAM;
DR   O46515, CP11A_HORSE;  P05108, CP11A_HUMAN;  Q2XV99, CP11A_MACFA;
DR   Q9EPT4, CP11A_MESAU;  Q9QZ82, CP11A_MOUSE;  Q07217, CP11A_ONCMY;
DR   P10612, CP11A_PIG  ;  Q28827, CP11A_RABIT;  P14137, CP11A_RAT  ;
DR   P79202, CP11A_SHEEP;
//
ID   1.14.15.7
DE   Choline monooxygenase.
CA   Choline + O(2) + 2 reduced ferredoxin + 2 H(+) = betaine aldehyde hydrate
CA   + H(2)O + 2 oxidized ferredoxin.
CF   Iron-sulfur; Magnesium.
CC   -!- Catalyzes the first step of glycine betaine synthesis.
CC   -!- In many bacteria, plants and animals, the osmoprotectant betaine is
CC       synthesized in two steps: (1) choline to betaine aldehyde and (2)
CC       betaine aldehyde to betaine.
CC   -!- Different enzymes are involved in the first reaction.
CC   -!- In plants, the reaction is catalyzed by this enzyme whereas in
CC       animals and many bacteria, it is catalyzed by either membrane-bound
CC       EC 1.1.99.1 or soluble EC 1.1.3.17.
CC   -!- The enzyme involved in the second step, EC 1.2.1.8, appears to be the
CC       same in plants, animals and bacteria.
CC   -!- In some bacteria, betaine is synthesized from glycine through the
CC       actions of EC 2.1.1.156 and EC 2.1.1.157.
CC   -!- Formerly EC 1.14.14.4.
DR   Q93XE1, CHMO_AMATR ;  Q9SZR0, CHMO_ARATH ;  Q9LKN0, CHMO_ATRHO ;
DR   O22553, CHMO_BETVU ;  O04121, CHMO_SPIOL ;
//
ID   1.14.15.8
DE   Steroid 15-beta-monooxygenase.
AN   CYP106A2.
AN   Steroid 15-beta-hydroxylase.
CA   Progesterone + reduced ferredoxin + O(2) = 15-beta-hydroxyprogesterone +
CA   oxidized ferredoxin + H(2)O.
CC   -!- The enzyme from Bacillus megaterium hydroxylates a variety of 3-oxo-
CC       Delta-4-steroids in position 15-beta.
CC   -!- Ring A-reduced, aromatic, and 3-beta-hydroxy-Delta-4-steroids do not
CC       serve as substrates.
PR   PROSITE; PDOC00081;
//
ID   1.14.16.1
DE   Phenylalanine 4-monooxygenase.
AN   PAH.
AN   Phenylalaninase.
AN   Phenylalanine 4-hydroxylase.
AN   Phenylalanine hydroxylase.
CA   L-phenylalanine + tetrahydrobiopterin + O(2) = L-tyrosine +
CA   4a-hydroxytetrahydrobiopterin.
CF   Iron.
CC   -!- The reaction involves an arene oxide which rearranges to give the
CC       phenolic hydroxy group.
CC   -!- This results in the hydrogen at C-4 migrating to C-3 and in part
CC       being retained, a process known as the NIH-shift.
CC   -!- The 4a-hydroxytetrahydrobiopterin formed can dehydrate to 6,7-
CC       dihydrobiopterin, both spontaneously and by the action of
CC       EC 4.2.1.96.
CC   -!- The 6,7-dihydrobiopterin can be enzymically reduced back to
CC       tetrahydrobiopterin, by EC 1.5.1.34, or slowly rearranges into the
CC       more stable compound 7,8-dihydrobiopterin.
CC   -!- Formerly EC 1.14.3.1 and EC 1.99.1.2.
PR   PROSITE; PDOC00316;
DR   Q2KIH7, PH4H_BOVIN ;  P90925, PH4H_CAEEL ;  Q9A7V7, PH4H_CAUCR ;
DR   P30967, PH4H_CHRVO ;  Q54XS1, PH4H_DICDI ;  P17276, PH4H_DROME ;
DR   P00439, PH4H_HUMAN ;  P16331, PH4H_MOUSE ;  P43334, PH4H_PSEAE ;
DR   Q8XU39, PH4H_RALSO ;  P04176, PH4H_RAT   ;  Q98D72, PH4H_RHILO ;
DR   Q9KLB8, PH4H_VIBCH ;
//
ID   1.14.16.2
DE   Tyrosine 3-monooxygenase.
AN   L-tyrosine hydroxylase.
AN   Tyrosine 3-hydroxylase.
AN   Tyrosine hydroxylase.
CA   L-tyrosine + tetrahydrobiopterin + O(2) = 3,4-dihydroxy-L-phenylalanine +
CA   4a-hydroxytetrahydrobiopterin.
CF   Iron.
CC   -!- Activated by phosphorylation, catalyzed by EC 2.7.11.27.
CC   -!- The 4a-hydroxytetrahydrobiopterin formed can dehydrate to 6,7-
CC       dihydrobiopterin, both spontaneously and by the action of
CC       EC 4.2.1.96.
CC   -!- The 6,7-dihydrobiopterin can be enzymically reduced back to
CC       tetrahydrobiopterin, by EC 1.5.1.34, or slowly rearranges into the
CC       more stable compound 7,8-dihydrobiopterin.
PR   PROSITE; PDOC00316;
DR   O42091, TY3H_ANGAN ;  P17289, TY3H_BOVIN ;  P90986, TY3H_CAEEL ;
DR   Q76IQ3, TY3H_CANFA ;  P18459, TY3H_DROME ;  P07101, TY3H_HUMAN ;
DR   P24529, TY3H_MOUSE ;  P11982, TY3H_PHASP ;  P04177, TY3H_RAT   ;
DR   O17446, TY3H_SCHMA ;
//
ID   1.14.16.3
DE   Anthranilate 3-monooxygenase.
AN   Anthranilate 3-hydroxylase.
AN   Anthranilic acid hydroxylase.
AN   Anthranilic hydroxylase.
CA   Anthranilate + tetrahydrobiopterin + O(2) = 3-hydroxyanthranilate +
CA   dihydrobiopterin + H(2)O.
CF   Iron.
//
ID   1.14.16.4
DE   Tryptophan 5-monooxygenase.
AN   Indoleacetic acid-5-hydroxylase.
AN   L-tryptophan hydroxylase.
AN   Tryptophan 5-hydroxylase.
AN   Tryptophan hydroxylase.
CA   L-tryptophan + tetrahydrobiopterin + O(2) = 5-hydroxy-L-tryptophan +
CA   4a-hydroxytetrahydrobiopterin.
CF   Iron.
CC   -!- Activated by phosphorylation, catalyzed by a Ca(2+)-activated protein
CC       kinase.
CC   -!- The 4a-hydroxytetrahydrobiopterin formed can dehydrate to 6,7-
CC       dihydrobiopterin, both spontaneously and by the action of
CC       EC 4.2.1.96.
CC   -!- The 6,7-dihydrobiopterin can be enzymically reduced back to
CC       tetrahydrobiopterin, by EC 1.5.1.34, or slowly rearranges into the
CC       more stable compound 7,8-dihydrobiopterin.
PR   PROSITE; PDOC00316;
DR   Q54XS1, PH4H_DICDI ;  P17276, PH4H_DROME ;  P70080, TPH1_CHICK ;
DR   P17752, TPH1_HUMAN ;  P17532, TPH1_MOUSE ;  P17290, TPH1_RABIT ;
DR   P09810, TPH1_RAT   ;  Q0EAB8, TPH2_HORSE ;  Q8IWU9, TPH2_HUMAN ;
DR   Q2HZ26, TPH2_MACMU ;  Q8CGV2, TPH2_MOUSE ;  Q8CGU9, TPH2_RAT   ;
DR   Q92142, TPH_XENLA  ;
//
ID   1.14.16.5
DE   Alkylglycerol monooxygenase.
AN   Glyceryl etherase.
AN   Glyceryl-ether cleaving enzyme.
AN   Glyceryl-ether monooxygenase.
CA   1-alkyl-sn-glycerol + tetrahydrobiopterin + O(2) = 1-O-alkyl-sn-glycerol
CA   + dihydrobiopterin + H(2)O.
CF   Glutathione.
CC   -!- The enzyme cleaves alkylglycerols, but does not cleave
CC       alkenylglycerols (plasmalogens).
CC   -!- Requires phospholipids for full activity.
CC   -!- The product spontaneously breaks down to form a fatty aldehyde and
CC       glycerol.
CC   -!- Formerly EC 1.14.99.17.
DR   Q6NYE4, ALKMO_DANRE;  Q6ZNB7, ALKMO_HUMAN;  Q8BS35, ALKMO_MOUSE;
DR   A0JPQ8, ALKMO_RAT  ;  Q5M8F9, ALKMO_XENTR;
//
ID   1.14.16.6
DE   Mandelate 4-monooxygenase.
AN   L-mandelate 4-hydroxylase.
AN   Mandelic acid 4-hydroxylase.
CA   (S)-2-hydroxy-2-phenylacetate + tetrahydrobiopterin + O(2) = (S)-4-
CA   hydroxymandelate + dihydrobiopterin + H(2)O.
CF   Iron.
//
ID   1.14.17.1
DE   Dopamine beta-monooxygenase.
AN   Dopamine beta-hydroxylase.
CA   3,4-dihydroxyphenethylamine + ascorbate + O(2) = noradrenaline +
CA   dehydroascorbate + H(2)O.
CF   Copper.
CC   -!- Stimulated by fumarate.
CC   -!- Formerly EC 1.14.2.1.
PR   PROSITE; PDOC00080;
DR   P15101, DOPO_BOVIN ;  Q68CI2, DOPO_CANFA ;  Q9XTA0, DOPO_HORSE ;
DR   P09172, DOPO_HUMAN ;  Q64237, DOPO_MOUSE ;  Q05754, DOPO_RAT   ;
//
ID   1.14.17.2
DE   Transferred entry: 1.14.18.1.
//
ID   1.14.17.3
DE   Peptidylglycine monooxygenase.
AN   PAM.
AN   Peptidyl alpha-amidating enzyme.
AN   Peptidylglycine 2-hydroxylase.
AN   Peptidylglycine alpha-amidating monooxygenase.
CA   Peptidylglycine + ascorbate + O(2) = peptidyl(2-hydroxyglycine) +
CA   dehydroascorbate + H(2)O.
CF   Copper.
CC   -!- Peptidylglycines with a neutral amino acid residue in the penultimate
CC       position are the best substrates for the enzyme.
CC   -!- The product is unstable and dismutates to glyoxylate and the
CC       corresponding desglycine peptide amide, a reaction catalyzed by
CC       EC 4.3.2.5.
CC   -!- Involved in the final step of biosynthesis of alpha-melanotropin and
CC       related biologically active peptides.
PR   PROSITE; PDOC00080;
DR   P08478, AMDA_XENLA ;  P12890, AMDB_XENLA ;  P83388, AMDL_CAEEL ;
DR   P10731, AMD_BOVIN  ;  P19021, AMD_HUMAN  ;  P97467, AMD_MOUSE  ;
DR   P14925, AMD_RAT    ;  Q95XM2, PHM_CAEEL  ;  O01404, PHM_DROME  ;
//
ID   1.14.17.4
DE   Aminocyclopropanecarboxylate oxidase.
AN   1-aminocyclopropane-1-carboxylate oxidase.
AN   ACC oxidase.
AN   Ethylene-forming enzyme.
CA   1-aminocyclopropane-1-carboxylate + ascorbate + O(2) = ethylene + cyanide
CA   + dehydroascorbate + CO(2) + 2 H(2)O.
CF   Iron.
CC   -!- Requires CO(2) for activity.
CC   -!- In the enzyme from plants, the ethylene has signaling functions such
CC       as stimulation of fruit-ripening.
PR   PROSITE; PDOC51471;
DR   Q9ZUN4, ACCO1_ARATH;  Q09052, ACCO1_BRAJU;  Q04644, ACCO1_CUCME;
DR   Q76NT9, ACCO1_DICDI;  A6BM06, ACCO1_DICMU;  P31238, ACCO1_DORSP;
DR   Q00985, ACCO1_MALDO;  A2Z1W9, ACCO1_ORYSI;  Q0J1C1, ACCO1_ORYSJ;
DR   Q08506, ACCO1_PETHY;  P05116, ACCO1_SOLLC;  Q41931, ACCO2_ARATH;
DR   Q39705, ACCO2_DORSP;  O48882, ACCO2_MALDO;  P07920, ACCO2_SOLLC;
DR   O65378, ACCO3_ARATH;  P54847, ACCO3_CUCME;  Q08507, ACCO3_PETHY;
DR   Q06588, ACCO4_ARATH;  Q08508, ACCO4_PETHY;  P24157, ACCO4_SOLLC;
DR   Q0WPW4, ACCO5_ARATH;  P31237, ACCO_ACTDE ;  Q9ZQZ1, ACCO_DENCR ;
DR   P31528, ACCO_DIACA ;  Q8S932, ACCO_DIOKA ;  Q9FR99, ACCO_MUSAC ;
DR   P31239, ACCO_PEA   ;  P19464, ACCO_PERAE ;  Q9MB94, ACCO_PRUMU ;
DR   Q43792, ACCO_TOBAC ;
//
ID   1.14.18.1
DE   Monophenol monooxygenase.
AN   Cresolase.
AN   Monophenol oxidase.
AN   Phenolase.
AN   Tyrosinase.
CA   L-tyrosine + L-dopa + O(2) = L-dopa + dopaquinone + H(2)O.
CF   Copper.
CC   -!- A group of copper proteins that also catalyze the reaction of
CC       EC 1.10.3.1, if only 1,2-benzenediols are available as substrate.
CC   -!- Formerly EC 1.14.17.2.
PR   PROSITE; PDOC00398;
DR   Q27451, PRP1_BOMMO ;  O44249, PRP1_MANSE ;  P85046, PRP1_SIMDA ;
DR   Q27452, PRP2_BOMMO ;  Q25519, PRP2_MANSE ;  Q9V521, PRPA3_DROME;
DR   Q8I1F6, PRPD3_DROER;  Q9W1V6, PRPD3_DROME;  O42713, TYRO_AGABI ;
DR   Q8J130, TYRO_ASPFU ;  Q00234, TYRO_ASPOR ;  Q8MIU0, TYRO_BOVIN ;
DR   P54834, TYRO_CANFA ;  P55024, TYRO_CHICK ;  Q08410, TYRO_COTJA ;
DR   P55033, TYRO_FELCA ;  Q9BDE0, TYRO_GORGO ;  P14679, TYRO_HUMAN ;
DR   P11344, TYRO_MOUSE ;  P00440, TYRO_NEUCR ;  P55025, TYRO_ORYLA ;
DR   Q04604, TYRO_PELNI ;  P55026, TYRO_PELSI ;  A7BHQ9, TYRO_PHONA ;
DR   Q92396, TYRO_PODAS ;  P33180, TYRO_RHIME ;  P07524, TYRO_STRAT ;
DR   P06845, TYRO_STRGA ;  P55022, TYRO_STRGB ;  P55023, TYRO_STRLN ;
//
ID   1.14.18.2
DE   CMP-N-acetylneuraminate monooxygenase.
AN   CMP-N-acetylneuraminate hydroxylase.
AN   CMP-N-acetylneuraminic acid hydroxylase.
AN   CMP-Neu5Ac hydroxylase.
AN   Cytidine monophosphoacetylneuraminate monooxygenase.
CA   CMP-N-acetylneuraminate + 2 ferrocytochrome b5 + O(2) + 2 H(+) = CMP-N-
CA   glycoloylneuraminate + 2 ferricytochrome b5 + H(2)O.
CF   Iron; Iron-sulfur.
CC   -!- The ferricytochrome b5 produced is reduced by NADH and EC 1.6.2.2.
CC   -!- The enzyme can be activated by Fe(2+) or Fe(3+).
CC   -!- Formerly EC 1.14.13.45 and EC 1.14.99.18.
DR   Q95V11, CMAH_ASTRU ;  Q9WV23, CMAH_CRIGR ;  Q6GML1, CMAH_DANRE ;
DR   Q8MJC8, CMAH_GORGO ;  Q9TUJ2, CMAH_MACMU ;  Q61419, CMAH_MOUSE ;
DR   Q8MJD0, CMAH_PANPA ;  O97598, CMAH_PANTR ;  O19074, CMAH_PIG   ;
DR   Q8MJC6, CMAH_PONPY ;  Q8AVF5, CMAH_XENLA ;
//
ID   1.14.18.3
DE   Methane monooxygenase (particulate).
CA   Methane + quinol + O(2) = methanol + quinone + H(2)O.
CF   Copper.
CC   -!- It is membrane-bound, in contrast to the soluble EC 1.14.13.25.
//
ID   1.14.19.1
DE   Stearoyl-CoA 9-desaturase.
AN   Acyl-CoA desaturase.
AN   Delta(9)-desaturase.
AN   Fatty acid desaturase.
AN   Stearoyl-CoA desaturase.
CA   Stearoyl-CoA + 2 ferrocytochrome b5 + O(2) + 2 H(+) = oleoyl-CoA +
CA   2 ferricytochrome b5 + 2 H(2)O.
CF   Iron.
CC   -!- The liver enzyme is an enzyme system involving cytochrome b5 and
CC       EC 1.6.2.2.
CC   -!- The ferricytochrome b5 produced is reduced by NADH and EC 1.6.2.2.
CC   -!- Formerly EC 1.14.99.5.
PR   PROSITE; PDOC00399;
DR   Q12618, ACO1_AJECA ;  O94523, ACO1_SCHPO ;  P21147, ACO1_YEAST ;
DR   P13516, ACOD1_MOUSE;  P07308, ACOD1_RAT  ;  P13011, ACOD2_MOUSE;
DR   Q6P7B9, ACOD2_RAT  ;  Q9TT94, ACOD_BOVIN ;  Q95MI7, ACOD_CAPHI ;
DR   Q92038, ACOD_CYPCA ;  O00767, ACOD_HUMAN ;  Q64420, ACOD_MESAU ;
DR   O02858, ACOD_PIG   ;  O62849, ACOD_SHEEP ;  Q2KIA4, SCD5_BOVIN ;
DR   Q86SK9, SCD5_HUMAN ;
//
ID   1.14.19.2
DE   Acyl-[acyl-carrier-protein] desaturase.
AN   Stearyl acyl carrier protein desaturase.
AN   Stearyl-ACP desaturase.
CA   Stearoyl-[acyl-carrier-protein] + reduced acceptor + O(2) = oleoyl-[acyl-
CA   carrier-protein] + acceptor + 2 H(2)O.
CC   -!- The enzyme from safflower is specific for stearoyl-[acyl-carrier
CC       protein]; that from Euglena acts on derivatives of a number of long-
CC       chain fatty acids.
CC   -!- Requires ferredoxin.
CC   -!- Formerly EC 1.14.99.6.
PR   PROSITE; PDOC00399;
DR   Q9LF04, STAD1_ARATH;  B8A7A3, STAD1_ORYSI;  Q8LJJ9, STAD1_ORYSJ;
DR   Q9M881, STAD2_ARATH;  A2WYF4, STAD2_ORYSI;  Q8S059, STAD2_ORYSJ;
DR   Q9LF05, STAD3_ARATH;  B8AIC3, STAD3_ORYSI;  B9F058, STAD3_ORYSJ;
DR   Q9M880, STAD4_ARATH;  Q84MF1, STAD4_ORYSJ;  Q9M879, STAD5_ARATH;
DR   A2XSL4, STAD5_ORYSI;  Q40731, STAD5_ORYSJ;  Q84VY3, STAD6_ARATH;
DR   A2YS71, STAD6_ORYSI;  Q0J7E4, STAD6_ORYSJ;  O22832, STAD7_ARATH;
DR   A2YS76, STAD7_ORYSI;  Q6Z1I5, STAD7_ORYSJ;  Q01771, STADS_BRANA;
DR   P29108, STAD_BRANA ;  P22243, STAD_CARTI ;  P32063, STAD_CORSA ;
DR   P32061, STAD_CUCSA ;  O24428, STAD_ELAGV ;  Q42770, STAD_GOSHI ;
DR   Q96456, STAD_HELAN ;  P32062, STAD_LINUS ;  Q43593, STAD_OLEEU ;
DR   P22337, STAD_RICCO ;  Q01753, STAD_SIMCH ;  Q41319, STAD_SOLCO ;
DR   P46253, STAD_SOLTU ;  Q42807, STAD_SOYBN ;  P28645, STAD_SPIOL ;
//
ID   1.14.19.3
DE   Linoleoyl-CoA desaturase.
AN   Delta(6)-acyl CoA desaturase.
AN   Delta(6)-desaturase.
AN   Delta(6)-fatty acyl-CoA desaturase.
AN   Fatty acid 6-desaturase.
AN   Fatty acid Delta(6)-desaturase.
AN   Linoleate desaturase.
AN   Linoleic acid desaturase.
AN   Linoleic desaturase.
AN   Linoleoyl CoA desaturase.
AN   Linoleoyl-coenzyme A desaturase.
AN   Long-chain fatty acid Delta(6)-desaturase.
CA   Linoleoyl-CoA + AH(2) + O(2) = gamma-linolenoyl-CoA + A + 2 H(2)O.
CF   Iron.
CC   -!- The rat liver enzyme is an enzyme system involving cytochrome b5 and
CC       EC 1.6.2.2.
CC   -!- Formerly EC 1.14.99.25.
DR   Q08871, LLCD_SYNY3 ;
//
ID   1.14.19.4
DE   Delta(8)-fatty-acid desaturase.
AN   Delta(8)-desaturase.
AN   Delta(8)-sphingolipid desaturase.
AN   EFD1.
AN   SLD.
CA   Phytosphinganine + reduced acceptor + O(2) = Delta(8)-phytosphingenine +
CA   acceptor + 2 H(2)O.
CC   -!- This enzyme, which has been found mainly in plants, introduces a
CC       double bond at Delta(8) of C(18) and C(20) fatty acids.
CC   -!- The enzyme from the marine microalga Euglena gracilis requires a
CC       double bond to be present at Delta(11) and is most active with 20:3
CC       Delta(11,14,17) and 20:2 Delta(11,14) as substrates, although it can
CC       also desaturate 20:1 Delta(11).
CC   -!- The Delta(8)-desaturation pathway represents an alternate pathway for
CC       the synthesis of the polyunsaturated fatty acids arachidonate (C20:4
CC       Delta(5,14)) and eicosapentaenoate (C20:5 Delta(5,17)) in organisms
CC       lacking a Delta(6)-desaturase.
CC   -!- Formerly EC 1.14.19.n1.
PR   PROSITE; PDOC00170;
//
ID   1.14.19.5
DE   Delta(11)-fatty-acid desaturase.
AN   Delta(11) desaturase.
AN   Delta(11)-palmitoyl-CoA desaturase.
AN   Fatty acid Delta(11)-desaturase.
AN   Z/E11-desaturase.
CA   Acyl-CoA + reduced acceptor + O(2) = Delta(11)-acyl-CoA + acceptor +
CA   2 H(2)O.
CC   -!- In common with front-end desaturases involved in the synthesis of
CC       polyunsaturated fatty acids (PUFAs), this membrane-bound enzyme has a
CC       cytochrome b5-like domain at the N-terminus and contains three
CC       histidine boxes that are critical for desaturase activity.
CC   -!- The enzyme from the marine microalga Thalassiosira pseudonana
CC       specifically desaturates palmitic acid 16:0 to 16:1-Delta(11) whereas
CC       that from the leafroller moth Choristoneura rosaceana desaturates
CC       myristic acid 14:0 to 14:1-Delta(11).
CC   -!- 16:1-Delta(11) represents an important precursor for pheromone
CC       synthesis in insect cells, although its function in microalgae is
CC       currently unknown.
CC   -!- The enzyme from the Egyptian cotton leafworm Spodoptera littoralis
CC       has a preference for palmitoyl-CoA as substrate and for NADH rather
CC       than NADPH as reduced acceptor.
CC   -!- Formerly EC 1.14.19.n2.
//
ID   1.14.19.6
DE   Delta(12)-fatty-acid desaturase.
AN   Delta(12) desaturase.
AN   Delta(12) fatty acid desaturase.
AN   Delta(12)(omega-6)-desaturase.
AN   Delta(12)-desaturase.
AN   Oleoyl-CoA Delta(12) desaturase.
CA   Acyl-CoA + reduced acceptor + O(2) = Delta(12)-acyl-CoA + acceptor +
CA   2 H(2)O.
CC   -!- In the yeast Lipomyces starkeyi and in the American cockroach
CC       Periplaneta americana, this microsomal enzyme converts oleoyl-CoA
CC       into linoleoyl-CoA.
CC   -!- In the moths Cadra cautella and Spodoptera, the enzyme converts (Z)-
CC       9-tetradecenoic acid into (9Z,12E)-tetradeca-9,12-dienoic acid, which
CC       is reduced and acetylated to form the acetate ester pheromone.
CC   -!- Formerly EC 1.14.19.n3.
PR   PROSITE; PDOC00399;
//
ID   1.14.19.7
DE   (S)-2-hydroxypropylphosphonic acid epoxidase.
AN   (S)-2-hydroxypropylphosphonate epoxidase.
AN   2-hydroxypropylphosphonic acid epoxidase.
AN   HPP epoxidase.
CA   (S)-2-hydroxypropylphosphonate + NADH + O(2) = (1R,2S)-
CA   epoxypropylphosphonate + H(2)O + 2 NAD(+).
CF   Iron.
CC   -!- FMN is required to mediate the transfer of reducing equivalents from
CC       NADH to the active site iron.
CC   -!- This is the last enzyme in the biosynthetic pathway of fosfomycin,
CC       a broad-spectrum antibiotic produced by certain Streptomyces species.
//
ID   1.14.19.n1
DE   Transferred entry: 1.14.19.4.
//
ID   1.14.19.n2
DE   Transferred entry: 1.14.19.5.
//
ID   1.14.19.n3
DE   Transferred entry: 1.14.19.6.
//
ID   1.14.20.1
DE   Deacetoxycephalosporin-C synthase.
AN   DAOC synthase.
AN   DAOCS.
AN   Penicillin N expandase.
CA   Penicillin N + 2-oxoglutarate + O(2) = deacetoxycephalosporin C +
CA   succinate + CO(2) + H(2)O.
CC   -!- Forms part of the penicillin biosynthesis pathway.
PR   PROSITE; PDOC00165;
PR   PROSITE; PDOC51471;
DR   Q03047, CEFE_NOCLA ;  P18548, CEFE_STRCL ;  P11935, EXPA_CEPAC ;
//
ID   1.14.21.1
DE   (S)-stylopine synthase.
AN   (S)-cheilanthifoline oxidase (methylenedioxy-bridge-forming).
CA   (S)-cheilanthifoline + NADPH + O(2) = (S)-stylopine + NADP(+) + 2 H(2)O.
CF   Heme-thiolate.
CC   -!- Catalyzes an oxidative reaction that does not incorporate oxygen into
CC       the product.
CC   -!- Forms the second methylenedioxy bridge of the protoberberine alkaloid
CC       stylopine from oxidative ring closure of adjacent phenolic and
CC       methoxy groups of cheilanthifoline.
CC   -!- Formerly EC 1.1.3.32.
//
ID   1.14.21.2
DE   (S)-cheilanthifoline synthase.
AN   (S)-scoulerine oxidase (methylenedioxy-bridge-forming).
CA   (S)-scoulerine + NADPH + O(2) = (S)-cheilanthifoline + NADP(+) + 2 H(2)O.
CF   Heme-thiolate.
CC   -!- Catalyzes an oxidative reaction that does not incorporate oxygen into
CC       the product.
CC   -!- Forms the methylenedioxy bridge of the protoberberine alkaloid
CC       cheilanthifoline from oxidative ring closure of adjacent phenolic and
CC       methoxy groups of scoulerine.
CC   -!- Formerly EC 1.1.3.33.
//
ID   1.14.21.3
DE   Berbamunine synthase.
AN   (S)-N-methylcoclaurine oxidase (C-O phenol-coupling).
CA   (S)-N-methylcoclaurine + (R)-N-methylcoclaurine + NADPH + O(2) =
CA   berbamunine + NADP(+) + 2 H(2)O.
CF   Heme-thiolate.
CC   -!- Forms the bisbenzylisoquinoline alkaloid berbamunine by phenol
CC       oxidation of N-methylcoclaurine without the incorporation of oxygen
CC       into the product.
CC   -!- Reaction of 2 molecules of (R)-N-methylcoclaurine gives the dimer
CC       guattagaumerine.
CC   -!- Formerly EC 1.1.3.34.
PR   PROSITE; PDOC00081;
DR   P47195, C80A1_BERST;
//
ID   1.14.21.4
DE   Salutaridine synthase.
AN   (R)-reticuline oxidase (C-C phenol-coupling).
CA   (R)-reticuline + NADPH + O(2) = salutaridine + NADP(+) + 2 H(2)O.
CF   Heme-thiolate.
CC   -!- Forms the morphinan alkaloid salutaridine by intramolecular phenol
CC       oxidation of reticuline without the incorporation of oxygen into the
CC       product.
CC   -!- Formerly EC 1.1.3.35.
PR   PROSITE; PDOC00081;
//
ID   1.14.21.5
DE   (S)-canadine synthase.
AN   (S)-tetrahydroberberine synthase.
AN   (S)-tetrahydrocolumbamine oxidase (methylenedioxy-bridge-forming).
CA   (S)-tetrahydrocolumbamine + NADPH + O(2) = (S)-canadine + NADP(+) +
CA   2 H(2)O.
CF   Heme-thiolate.
CC   -!- Catalyzes an oxidative reaction that does not incorporate oxygen into
CC       the product.
CC   -!- Oxidation of the methoxyphenol group of the alkaloid
CC       tetrahydrocolumbamine results in the formation of the methylenedioxy
CC       bridge of canadine.
CC   -!- Formerly EC 1.1.3.36.
PR   PROSITE; PDOC00081;
DR   Q948Y1, C719A_COPJA;
//
ID   1.14.21.6
DE   Lathosterol oxidase.
AN   5-DES.
AN   Delta(7)-sterol 5-desaturase.
AN   Delta(7)-sterol Delta(5)-dehydrogenase.
AN   Delta(7)-sterol-C5(6)-desaturase.
AN   Lathosterol 5-desaturase.
CA   5-alpha-cholest-7-en-3-beta-ol + NAD(P)H + O(2) = cholesta-5,7-dien-3-
CA   beta-ol + NAD(P)(+) + 2 H(2)O.
CC   -!- This enzyme catalyzes the introduction of a C5 double bond into the B
CC       ring of Delta(7)-sterols to yield the corresponding Delta(5,7)-
CC       sterols in mammals, yeast and plants.
CC   -!- Forms part of the plant sterol biosynthesis pathway.
CC   -!- Formerly EC 1.3.3.2.
DR   Q39208, SC5D1_ARATH;  Q9M883, SC5D2_ARATH;  O75845, SC5D_HUMAN ;
DR   O88822, SC5D_MOUSE ;  Q9ZT29, SC5D_TOBAC ;
//
ID   1.14.21.7
DE   Biflaviolin synthase.
AN   CYP158A2.
CA   (1) 2 flaviolin + NADPH + O(2) = 3,3'-biflaviolin + NADP(+) + 2 H(2)O.
CA   (2) 2 flaviolin + NADPH + O(2) = 3,8'-biflaviolin + NADP(+) + 2 H(2)O.
CC   -!- This cytochrome-P450 enzyme, from the soil-dwelling bacterium
CC       Streptomyces coelicolor A3(2), catalyzes a phenol oxidation
CC       C-C coupling reaction, which results in the polymerization of
CC       flaviolin to form biflaviolin or triflaviolin without the
CC       incorporation of oxygen into the product.
CC   -!- The products are highly conjugated pigments that protect the
CC       bacterium from the deleterious effects of UV irradiation.
PR   PROSITE; PDOC00081;
//
ID   1.14.21.8
DE   Pseudobaptigenin synthase.
CA   (1) Calycosin + NADPH + O(2) = pseudobaptigenin + NADP(+) + 2 H(2)O.
CA   (2) Pratensein + NADPH + O(2) = 5-hydroxypseudobaptigenin + NADP(+) +
CA   2 H(2)O.
CF   Heme-thiolate.
CC   -!- Catalyzes an oxidative reaction that does not incorporate oxygen into
CC       the product.
CC   -!- Catalyzes a step in the biosynthesis of (-)-maackiain, the main
CC       pterocarpan phytoalexin in chickpea (Cicer arietinum).
//
ID   1.14.99.1
DE   Prostaglandin-endoperoxide synthase.
AN   PG synthetase.
AN   Prostaglandin G/H synthase.
AN   Prostaglandin synthase.
AN   Prostaglandin synthetase.
CA   Arachidonate + AH(2) + 2 O(2) = prostaglandin H(2) + A + H(2)O.
CC   -!- Acts both as a dioxygenase and as a peroxidase.
DR   O62664, PGH1_BOVIN ;  P23219, PGH1_HUMAN ;  P22437, PGH1_MOUSE ;
DR   O97554, PGH1_RABIT ;  Q63921, PGH1_RAT   ;  P05979, PGH1_SHEEP ;
DR   O62698, PGH2_BOVIN ;  P70682, PGH2_CAVPO ;  P27607, PGH2_CHICK ;
DR   O19183, PGH2_HORSE ;  P35354, PGH2_HUMAN ;  Q05769, PGH2_MOUSE ;
DR   O62725, PGH2_MUSVI ;  O02768, PGH2_RABIT ;  P35355, PGH2_RAT   ;
DR   P79208, PGH2_SHEEP ;
//
ID   1.14.99.2
DE   Kynurenine 7,8-hydroxylase.
CA   Kynurenate + AH(2) + O(2) = 7,8-dihydro-7,8-dihydroxykynurenate + A.
CC   -!- Formerly EC 1.14.1.4.
//
ID   1.14.99.3
DE   Heme oxygenase.
AN   Heme oxidase.
AN   Heme oxygenase (decyclizing).
CA   Heme + 3 AH(2) + 3 O(2) = biliverdin + Fe(2+) + CO + 3 A + 3 H(2)O.
CC   -!- Requires NAD(P)H and EC 1.6.2.4.
CC   -!- The terminal oxygen atoms that are incorporated into the carbonyl
CC       groups of pyrrole rings A and B of biliverdin are derived from two
CC       separate oxygen molecules.
CC   -!- The third oxygen molecule provides the oxygen atom that converts the
CC       alpha-carbon to CO.
CC   -!- The central iron is kept in the reduced state by NAD(P)H.
PR   PROSITE; PDOC00512;
DR   O48782, HMOX1_ARATH;  Q5E9F2, HMOX1_BOVIN;  P14791, HMOX1_CHICK;
DR   P09601, HMOX1_HUMAN;  P14901, HMOX1_MOUSE;  Q69XJ4, HMOX1_ORYSJ;
DR   P32394, HMOX1_PIG  ;  Q5R7E3, HMOX1_PONAB;  P06762, HMOX1_RAT  ;
DR   P30519, HMOX2_HUMAN;  Q2PG53, HMOX2_MACFA;  O70252, HMOX2_MOUSE;
DR   P43242, HMOX2_RABIT;  P23711, HMOX2_RAT  ;  Q9C9L4, HMOX3_ARATH;
DR   O70453, HMOX3_RAT  ;  Q9LQC0, HMOX4_ARATH;  O73688, HMOX_TAKRU ;
DR   P71119, HMUO_CORDI ;  Q8YVS7, HO1_NOSS1  ;  P72849, HO1_SYNY3  ;
DR   P74133, HO2_SYNY3  ;  O78497, HO_GUITH   ;  P51271, HO_PORPU   ;
DR   Q1XDL5, HO_PORYE   ;  O19998, HO_RHOVL   ;  C3PAD1, ISDG_BACAA ;
DR   C3L7Z8, ISDG_BACAC ;  A0RJE3, ISDG_BACAH ;  Q81L50, ISDG_BACAN ;
DR   B7JR48, ISDG_BACC0 ;  Q72ZK2, ISDG_BACC1 ;  B7IJU1, ISDG_BACC2 ;
DR   C1ETY1, ISDG_BACC3 ;  B7HF56, ISDG_BACC4 ;  B7HRI4, ISDG_BACC7 ;
DR   B9J044, ISDG_BACCQ ;  Q812Q3, ISDG_BACCR ;  Q633Q1, ISDG_BACCZ ;
DR   Q9K7R6, ISDG_BACHD ;  Q6HCY5, ISDG_BACHK ;  Q5WCF2, ISDG_BACSK ;
DR   A9VJK2, ISDG_BACWK ;  Q7AP29, ISDG_LISIN ;  C1KZZ5, ISDG_LISMC ;
DR   Q723G7, ISDG_LISMF ;  B8DCJ3, ISDG_LISMH ;  Q92EH3, ISDG_LISMO ;
DR   A0AFT8, ISDG_LISW6 ;  A7WXE5, ISDG_STAA1 ;  Q2FHU5, ISDG_STAA3 ;
DR   Q2FZE2, ISDG_STAA8 ;  Q2YX89, ISDG_STAAB ;  Q5HGU8, ISDG_STAAC ;
DR   Q99UW8, ISDG_STAAM ;  Q7A649, ISDG_STAAN ;  Q6GHV0, ISDG_STAAR ;
DR   Q6GA79, ISDG_STAAS ;  A8Z1R5, ISDG_STAAT ;  Q8NX62, ISDG_STAAW ;
DR   Q5HM56, ISDG_STAEQ ;  Q8CRK4, ISDG_STAES ;  Q4L849, ISDG_STAHJ ;
DR   Q49ZB8, ISDG_STAS1 ;  Q2FK96, ISDI_STAA3 ;  Q2G1J2, ISDI_STAA8 ;
DR   Q5HJK5, ISDI_STAAC ;  Q99X56, ISDI_STAAM ;  Q7A827, ISDI_STAAN ;
DR   Q6GKE0, ISDI_STAAR ;  Q6GCW1, ISDI_STAAS ;  Q7A1Y8, ISDI_STAAW ;
//
ID   1.14.99.4
DE   Progesterone monooxygenase.
AN   Progesterone hydroxylase.
CA   Progesterone + AH(2) + O(2) = testosterone acetate + A + H(2)O.
CC   -!- Has a wide specificity.
CC   -!- A single enzyme from Cylindrocarpon radicicola (EC 1.14.13.54)
CC       catalyzes both this reaction and that catalyzed by EC 1.14.99.12.
//
ID   1.14.99.5
DE   Transferred entry: 1.14.19.1.
//
ID   1.14.99.6
DE   Transferred entry: 1.14.19.2.
//
ID   1.14.99.7
DE   Squalene monooxygenase.
AN   Squalene epoxidase.
CA   Squalene + AH(2) + O(2) = (S)-squalene-2,3-epoxide + A + H(2)O.
CF   FAD.
CC   -!- This enzyme, together with EC 5.4.99.7, was formerly known as
CC       squalene oxidocyclase.
CC   -!- Formerly EC 1.14.1.3 and EC 1.99.1.13.
DR   O65404, ERG11_ARATH;  O65727, ERG11_BRANA;  O65402, ERG12_ARATH;
DR   O65726, ERG12_BRANA;  O65403, ERG13_ARATH;  Q75F69, ERG1_ASHGO ;
DR   Q92206, ERG1_CANAL ;  O13306, ERG1_CANGA ;  Q14534, ERG1_HUMAN ;
DR   P52019, ERG1_MOUSE ;  O48651, ERG1_PANGI ;  P52020, ERG1_RAT   ;
DR   Q9C1W3, ERG1_SCHPO ;  P32476, ERG1_YEAST ;
//
ID   1.14.99.8
DE   Transferred entry: 1.14.14.1.
//
ID   1.14.99.9
DE   Steroid 17-alpha-monooxygenase.
AN   Cytochrome p450 XVIIA1.
AN   Steroid 17-alpha-hydroxylase.
AN   Steroid 17-alpha-hydroxylase/17,20 lyase.
CA   A steroid + AH(2) + O(2) = a 17-alpha-hydroxysteroid + A + H(2)O.
CF   Heme-thiolate.
CC   -!- Formerly EC 1.14.1.7 and EC 1.99.1.9.
PR   PROSITE; PDOC00081;
DR   Q9GMC7, CP17A_BISBI;  P05185, CP17A_BOVIN;  Q9N0U7, CP17A_CAPHI;
DR   Q64410, CP17A_CAVPO;  P12394, CP17A_CHICK;  Q9GMC8, CP17A_FELCA;
DR   Q95328, CP17A_HORSE;  P05093, CP17A_HUMAN;  O73853, CP17A_ICTPU;
DR   Q2XVA1, CP17A_MACFA;  Q8HYM9, CP17A_MACMU;  P70687, CP17A_MESAU;
DR   P27786, CP17A_MOUSE;  P30437, CP17A_ONCMY;  P70085, CP17A_ORYLA;
DR   Q8HYN1, CP17A_PANTR;  Q8HYN0, CP17A_PAPCY;  Q9GLD2, CP17A_PAPHU;
DR   Q91Z85, CP17A_PERLE;  P19100, CP17A_PIG  ;  O57525, CP17A_RANDY;
DR   P11715, CP17A_RAT  ;  Q29497, CP17A_SHEEP;  Q92113, CP17A_SQUAC;
//
ID   1.14.99.10
DE   Steroid 21-monooxygenase.
AN   Cytochrome p450 XXIA1.
AN   Steroid 21-hydroxylase.
CA   A steroid + AH(2) + O(2) = a 21-hydroxysteroid + A + H(2)O.
CF   Heme-thiolate.
CC   -!- Formerly EC 1.14.1.8 and EC 1.99.1.11.
PR   PROSITE; PDOC00081;
DR   P00191, CP21A_BOVIN;  Q8WNW0, CP21A_CANFA;  Q2LCM1, CP21A_CANLU;
DR   Q2LA60, CP21A_FELCA;  P08686, CP21A_HUMAN;  Q2LA59, CP21A_LYNLY;
DR   P03940, CP21A_MOUSE;  P15540, CP21A_PIG  ;  Q64562, CP21A_RAT  ;
//
ID   1.14.99.11
DE   Estradiol 6-beta-monooxygenase.
AN   Estradiol 6-beta-hydroxylase.
CA   Estradiol-17-beta + AH(2) + O(2) = 6-beta-hydroxyestradiol-17-beta + A +
CA   H(2)O.
CC   -!- Formerly EC 1.14.1.10.
//
ID   1.14.99.12
DE   Androst-4-ene-3,17-dione monooxygenase.
AN   4-androstene-3,17-dione monooxygenase.
AN   Androst-4-ene-3,17-dione 17-oxidoreductase.
AN   Androstene-3,17-dione hydroxylase.
AN   Androstenedione monooxygenase.
CA   Androst-4-ene-3,17-dione + AH(2) + O(2) = 3-oxo-13,17-secoandrost-4-ene-
CA   17,13-alpha-lactone + A + H(2)O.
CC   -!- Has a wide specificity.
CC   -!- A single enzyme from Cylindrocarpon radicicola (EC 1.14.13.54)
CC       catalyzes both this reaction and that catalyzed by EC 1.14.99.4.
//
ID   1.14.99.13
DE   Transferred entry: 1.14.13.23.
//
ID   1.14.99.14
DE   Progesterone 11-alpha-monooxygenase.
AN   Progesterone 11-alpha-hydroxylase.
CA   Progesterone + AH(2) + O(2) = 11-alpha-hydroxyprogesterone + A + H(2)O.
//
ID   1.14.99.15
DE   4-methoxybenzoate monooxygenase (O-demethylating).
AN   4-methoxybenzoate O-demethylase.
CA   4-methoxybenzoate + AH(2) + O(2) = 4-hydroxybenzoate + formaldehyde + A +
CA   H(2)O.
CF   Flavoprotein; Iron-sulfur.
CC   -!- The bacterial enzyme consists of a ferredoxin-type protein and an
CC       iron-sulfur flavoprotein (FMN).
CC   -!- Also acts on 4-ethoxybenzoate, N-methyl-4-aminobenzoate and toluate.
CC   -!- The fungal enzyme acts best on veratrate.
//
ID   1.14.99.16
DE   Transferred entry: 1.14.13.72.
//
ID   1.14.99.17
DE   Transferred entry: 1.14.16.5.
//
ID   1.14.99.18
DE   Deleted entry.
//
ID   1.14.99.19
DE   Plasmanylethanolamine desaturase.
AN   Alkylacylglycerophosphoethanolamine desaturase.
CA   O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + AH(2) + O(2) = O-1-
CA   alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + A + 2 H(2)O.
CF   Magnesium.
CC   -!- Either NADPH or NADH can act as AH(2).
CC   -!- May involve cytochrome b5.
CC   -!- Requires ATP.
//
ID   1.14.99.20
DE   Phylloquinone monooxygenase (2,3-epoxidizing).
AN   Phylloquinone epoxidase.
CA   Phylloquinone + AH(2) + O(2) = 2,3-epoxyphylloquinone + A + H(2)O.
//
ID   1.14.99.21
DE   Latia-luciferin monooxygenase (demethylating).
CA   Latia luciferin + AH(2) + 2 O(2) = oxidized Latia luciferin + CO(2) +
CA   formate + A + H(2)O + light.
CF   Flavoprotein.
CC   -!- Latia luciferin is (E)-2-methyl-4-(2,6,6-trimethyl-1-cyclohex-1-yl)-
CC       1-buten-1-ol formate.
CC   -!- The reaction possibly involves two enzymes, an oxygenase followed by
CC       a monooxygenase for the actual light-emitting step.
//
ID   1.14.99.22
DE   Ecdysone 20-monooxygenase.
CA   Ecdysone + AH(2) + O(2) = 20-hydroxyecdysone + A + H(2)O.
CF   Heme-thiolate.
CC   -!- An enzyme from insect fat body or malpighian tubules.
CC   -!- NADPH can act as ultimate hydrogen donor.
PR   PROSITE; PDOC00081;
DR   Q9VUF8, CP314_DROME;
//
ID   1.14.99.23
DE   3-hydroxybenzoate 2-monooxygenase.
AN   3-hydroxybenzoate 2-hydroxylase.
CA   3-hydroxybenzoate + AH(2) + O(2) = 2,3-dihydroxybenzoate + A + H(2)O.
//
ID   1.14.99.24
DE   Steroid 9-alpha-monooxygenase.
AN   Steroid 9-alpha-hydroxylase.
CA   Pregna-4,9(11)-diene-3,20-dione + AH(2) + O(2) = 9,11-alpha-epoxypregn-4-
CA   ene-3,20-dione + A + H(2)O.
CF   FMN; Iron-sulfur.
CC   -!- An enzyme system involving a flavoprotein (FMN) and two iron-sulfur
CC       proteins.
//
ID   1.14.99.25
DE   Transferred entry: 1.14.19.3.
//
ID   1.14.99.26
DE   2-hydroxypyridine 5-monooxygenase.
AN   2-hydroxypyridine oxygenase.
CA   2-hydroxypyridine + AH(2) + O(2) = 2,5-dihydroxypyridine + A + H(2)O.
CC   -!- Also oxidizes 2,5-dihydroxypyridine, but does not act on
CC       3-hydroxypyridine, 4-hydroxypyridine or 2,6-dihydroxypyridine.
//
ID   1.14.99.27
DE   Juglone 3-monooxygenase.
CA   5-hydroxy-1,4-naphthoquinone + AH(2) + O(2) = 3,5-dihydroxy-1,4-
CA   naphthoquinone + A + H(2)O.
CC   -!- Also acts on 1,4-naphthoquinone, naphthazarin and 2-chloro-1,4-
CC       naphthoquinone, but not on other related compounds.
//
ID   1.14.99.28
DE   Linalool 8-monooxygenase.
CA   3,7-dimethylocta-1,6-dien-3-ol + AH(2) + O(2) = (E)-3,7-dimethylocta-1,6-
CA   dien-3,8-diol + A + H(2)O.
CF   Heme-thiolate.
PR   PROSITE; PDOC00081;
DR   Q59723, CPXO_PSEPU ;
//
ID   1.14.99.29
DE   Deoxyhypusine monooxygenase.
AN   Deoxyhypusine dioxygenase.
AN   Deoxyhypusine hydroxylase.
AN   DOHH.
CA   Protein N(6)-(4-aminobutyl)-L-lysine + AH(2) + O(2) = protein N(6)-((R)-
CA   4-amino-2-hydroxybutyl)-L-lysine + A + H(2)O.
CC   -!- Catalyzes the final step in the formation of the amino acid hypusine
CC       in eukaryotic initiation factor 5A (eIF-5A) (formerly eIF-4D).
DR   Q2QXB3, DOHH1_ORYSJ;  Q2QLW3, DOHH2_ORYSJ;  Q94JW0, DOHH_ARATH ;
DR   Q752Z8, DOHH_ASHGO ;  A1CED0, DOHH_ASPCL ;  Q4WHG5, DOHH_ASPFU ;
DR   A2QXL3, DOHH_ASPNC ;  Q2UMQ8, DOHH_ASPOR ;  Q0VC53, DOHH_BOVIN ;
DR   Q17949, DOHH_CAEEL ;  Q59Z14, DOHH_CANAL ;  Q6FUV3, DOHH_CANGA ;
DR   Q2H0C0, DOHH_CHAGB ;  Q5ZIP3, DOHH_CHICK ;  Q1E9L2, DOHH_COCIM ;
DR   P0CN11, DOHH_CRYNB ;  P0CN10, DOHH_CRYNJ ;  Q7ZUX6, DOHH_DANRE ;
DR   Q6BKA6, DOHH_DEBHA ;  Q556G4, DOHH_DICDI ;  Q9V9U4, DOHH_DROME ;
DR   Q297S2, DOHH_DROPS ;  Q5AW32, DOHH_EMENI ;  Q8SV71, DOHH_ENCCU ;
DR   Q4HZ35, DOHH_GIBZE ;  Q9BU89, DOHH_HUMAN ;  Q6CV81, DOHH_KLULA ;
DR   Q96WP5, DOHH_LENED ;  Q99LN9, DOHH_MOUSE ;  A1DFW7, DOHH_NEOFI ;
DR   Q7S891, DOHH_NEUCR ;  Q0UHL8, DOHH_PHANO ;  Q5PPJ4, DOHH_RAT   ;
DR   Q9P6K9, DOHH_SCHPO ;  Q4PHU4, DOHH_USTMA ;  Q66KT3, DOHH_XENLA ;
DR   Q6CHJ7, DOHH_YARLI ;  P47120, DOHH_YEAST ;
//
ID   1.14.99.30
DE   Carotene 7,8-desaturase.
AN   Zeta-carotene desaturase.
CA   Neurosporene + AH(2) + O(2) = lycopene + A + 2 H(2)O.
CC   -!- Also acts on zeta-carotene twice to give lycopene and converts beta-
CC       zeacarotene to gamma-carotene, and pro-zeta-carotene to prolycopene
CC       (via double reaction).
DR   Q38893, ZDS_ARATH  ;  Q9SMJ3, ZDS_CAPAN  ;  Q9ZTP4, ZDS_MAIZE  ;
DR   O49901, ZDS_NARPS  ;  Q9R6X4, ZDS_NOSS1  ;  Q9SE20, ZDS_SOLLC  ;
DR   P74306, ZDS_SYNY3  ;  Q9FV46, ZDS_TARER  ;
//
ID   1.14.99.31
DE   Myristoyl-CoA 11-(E) desaturase.
CA   Myristoyl-CoA + NAD(P)H + O(2) = (E)-11-tetradecenoyl-CoA + NAD(P)(+) +
CA   2 H(2)O.
CC   -!- Involved in sex pheromone synthesis in Spodoptera littoralis.
CC   -!- (E)-11-tetradecenoyl-CoA is formed by stereospecific removal of the
CC       pro-R H at C-11 and the pro-S H at C-12.
CC   -!- EC 1.14.99.32 forms the Z-isomer by stereospecific cleavage of pro-R
CC       H at C-11 and C-12.
//
ID   1.14.99.32
DE   Myristoyl-CoA 11-(Z) desaturase.
CA   Myristoyl-CoA + NAD(P)H + O(2) = (Z)-11-tetradecenoyl-CoA + NAD(P)(+) +
CA   2 H(2)O.
CC   -!- Involved in sex pheromone synthesis in Spodoptera littoralis.
CC   -!- (Z)-11-tetradecenoyl-CoA is formed by stereospecific removal of H
CC       from the pro-R positions at C-11 and C-12.
CC   -!- EC 1.14.99.31 forms the E-isomer by removing the pro-R H group at
CC       C-11 and the pro-S H group at C-12.
//
ID   1.14.99.33
DE   Delta(12)-fatty acid dehydrogenase.
AN   Crepenynate synthase.
AN   Delta-12 fatty acid acetylenase.
AN   Linoleate Delta-12-fatty acid acetylenase (desaturase).
CA   Linoleate + AH(2) + O(2) = crepenynate + A + H(2)O.
CF   Iron.
DR   O81931, FAD12_CREAL;
//
ID   1.14.99.34
DE   Monoprenyl isoflavone epoxidase.
AN   Monoprenyl isoflavone monooxygenase.
CA   7-O-methylluteone + NADPH + O(2) = dihydrofurano derivatives + NADP(+) +
CA   H(2)O.
CF   FAD.
CC   -!- The enzyme has a high specificity for monoprenyl isoflavone.
CC   -!- The product of the prenyl epoxidation reaction contains an oxygen
CC       atom derived from O(2), but not from H(2)O.
CC   -!- It is slowly and nonenzymically converted into the corresponding
CC       dihydrofurano derivative.
//
ID   1.14.99.35
DE   Thiophene-2-carbonyl-CoA monooxygenase.
AN   Thiophene-2-carboxyl-CoA dehydrogenase.
AN   Thiophene-2-carboxyl-CoA hydroxylase.
AN   Thiophene-2-carboxyl-CoA monooxygenase.
CA   Thiophene-2-carbonyl-CoA + AH(2) + O(2) = 5-hydroxythiophene-2-carbonyl-
CA   CoA + A + H(2)O.
CF   Molybdenum.
CC   -!- Highly specific for thiophene-2-carbonyl-CoA.
CC   -!- Tetrazolium salts can act as electron acceptors.
//
ID   1.14.99.36
DE   Beta-carotene 15,15'-monooxygenase.
AN   Beta-carotene 15,15'-dioxygenase.
AN   Carotene 15,15'-dioxygenase.
AN   Carotene dioxygenase.
CA   Beta-carotene + O(2) = 2 retinal.
CF   Bile salt; Iron.
CC   -!- The reaction proceeds in three stages, epoxidation of the
CC       15,15'-double bond, hydration of the double bond leading to ring
CC       opening, and oxidative cleavage of the diol formed (cf.
CC       EC 1.14.15.6).
CC   -!- Thus only one atom of the dioxygen is incorporated into retinal.
CC   -!- Formerly EC 1.13.11.21 and EC 1.18.3.1.
DR   Q9I993, BCDO1_CHICK;  Q9HAY6, BCDO1_HUMAN;  Q9JJS6, BCDO1_MOUSE;
DR   Q91XT5, BCDO1_RAT  ;
//
ID   1.14.99.37
DE   Taxadiene 5-alpha-hydroxylase.
CA   Taxa-4,11-diene + AH(2) + O(2) = taxa-4(20),11-dien-5-alpha-ol + A +
CA   H(2)O.
CF   Heme-thiolate.
CC   -!- Involved in the biosynthesis of the diterpenoid antineoplastic drug
CC       Taxol (paclitaxel).
CC   -!- The reaction includes rearrangement of the 4(5)-double bond to a
CC       4(20)-double bond, possibly through allylic oxidation.
DR   Q6WG30, T5H_TAXCU  ;
//
ID   1.14.99.38
DE   Cholesterol 25-hydroxylase.
AN   Cholesterol 25-monooxygenase.
CA   Cholesterol + AH(2) + O(2) = 25-hydroxycholesterol + A + H(2)O.
CF   Iron.
CC   -!- Unlike most other sterol hydroxylases, this enzyme is not a
CC       cytochrome P-450.
CC   -!- Instead, it uses diiron cofactors to catalyze the hydroxylation of
CC       hydrophobic substrates.
CC   -!- The diiron cofactor can be either Fe-O-Fe or Fe-OH-Fe and is bound to
CC       the enzyme through interactions with clustered histidine or glutamate
CC       residues.
CC   -!- In cell cultures, this enzyme down-regulates cholesterol synthesis
CC       and the processing of sterol regulatory element binding proteins
CC       (SREBPs).
DR   O95992, CH25H_HUMAN;  Q9Z0F5, CH25H_MOUSE;  Q4G1G8, CH25H_PIG  ;
DR   Q4QQV7, CH25H_RAT  ;
//
ID   1.14.99.39
DE   Ammonia monooxygenase.
AN   AMO.
CA   Ammonia + AH(2) + O(2) = NH(2)OH + A + H(2)O.
CF   Copper; Iron.
CC   -!- The donor is membrane-bound.
CC   -!- Electrons are derived indirectly from ubiquinol.
//
ID   1.14.99.40
DE   5,6-dimethylbenzimidazole synthase.
CA   FMNH(2) + NADH + O(2) = 5,6-dimethylbenzimidazole + D-erythrose
CA   4-phosphate + NAD(+) + other product.
CC   -!- The C-2 of 5,6-dimethylbenzimidazole is derived from C-1' of the
CC       ribityl group of FMNH(2) and 2-H from the ribityl 1'-pro-(S)
CC       hydrogen.
CC   -!- The other product may be barbituric acid.
CC   -!- The stoichiometery of the reaction is not known.
//
ID   1.14.99.41
DE   All-trans-8'-apo-beta-carotenal 15,15'-oxygenase.
AN   8'-apo-beta-carotenal 15,15'-oxygenase.
CA   All-trans-8'-apo-beta-carotenal + O(2) = all-trans-retinal + 2,6-
CA   dimethyl-octa-2,4,6-trienedial.
CF   Iron.
CC   -!- The enzyme is involved in retinal biosynthesis in bacteria.
CC   -!- Formerly EC 1.14.99.n1.
DR   P74334, ACOX_SYNY3 ;
//
ID   1.14.99.42
DE   Zeaxanthin 7,8-dioxygenase.
AN   Zeaxanthin 7,8(7',8')-cleavage dioxygenase.
CA   Zeaxanthin + 2 O(2) = crocetin dialdehyde + 2 (3S)-3-hydroxycyclocitral.
CC   -!- Presumably the enzyme acts twice on zeaxanthin cleaving
CC       3-hydroxycyclocitral off each 3-hydroxy end group.
CC   -!- Formerly EC 1.14.99.n3.
DR   Q84K96, ZCD_CROSA  ;
//
ID   1.14.99.43
DE   Beta-amyrin 24-hydroxylase.
AN   CYP93E1.
AN   Sophoradiol 24-hydroxylase.
CA   (1) Beta-amyrin + AH(2) + O(2) = 24-hydroxy-beta-amyrin + A + H(2)O.
CA   (2) Sophoradiol + AH(2) + O(2) = 24-hydroxysophoradiol + A + H(2)O.
CF   Heme-thiolate.
DR   Q9XHC6, C93E1_SOYBN;
//
ID   1.14.99.44
DE   Diapolycopene oxygenase.
CA   4,4'-diapolycopene + 4 AH(2) + 4 O(2) = 4,4'-diapolycopenedial + 4 A +
CA   6 H(2)O.
CC   -!- Little activity with neurosporene or lycopene.
CC   -!- Involved in the biosynthesis of C(30) carotenoids such as
CC       staphyloxanthin.
CC   -!- The enzyme oxidizes each methyl group to the hydroxymethyl and then a
CC       dihydroxymethyl group, followed by the spontaneous loss of water to
CC       give an aldehyde group.
DR   Q2FDU3, CRTP_STAA3 ;  Q2FV57, CRTP_STAA8 ;  Q2YWE5, CRTP_STAAB ;
DR   Q5HCY6, CRTP_STAAC ;  Q53589, CRTP_STAAE ;  Q99R73, CRTP_STAAM ;
DR   Q7A3D9, CRTP_STAAN ;  Q6GDN5, CRTP_STAAR ;  Q6G6B0, CRTP_STAAS ;
DR   Q8NUQ3, CRTP_STAAW ;  Q4L978, CRTP_STAHJ ;
//
ID   1.14.99.45
DE   Carotene epsilon-monooxygenase.
AN   CYP97C1.
AN   LUT1.
CA   Alpha-carotene + O(2) + AH(2) = alpha-cryptoxanthin + A + H(2)O.
CF   Heme-thiolate.
CC   -!- Also acts on zeinoxanthin to give lutein.
DR   Q6TBX7, LUT1_ARATH ;
//
ID   1.14.99.n1
DE   Transferred entry: 1.14.99.41.
//
ID   1.14.99.n2
DE   Beta,beta-carotene 9',10'-oxygenase.
CA   Beta-carotene + O(2) = 10'-apo-beta-carotenal + beta-ionone.
CC   -!- The enzyme also cleaves lycopene.
DR   Q9BYV7, BCDO2_HUMAN;  Q8HXG8, BCDO2_MACFA;  Q99NF1, BCDO2_MOUSE;
DR   Q5RF16, BCDO2_PONAB;  Q7XJM2, CCD7_ARATH ;
//
ID   1.14.99.n3
DE   Transferred entry: 1.14.99.42.
//
ID   1.15.1.1
DE   Superoxide dismutase.
CA   2 superoxide + 2 H(+) = O(2) + H(2)O(2).
CF   Iron or manganese or (zinc and copper).
PR   PROSITE; PDOC00082;
PR   PROSITE; PDOC00083;
PR   PROSITE; PDOC00597;
DR   Q94EG3, NEC1_NICLS ;  Q9SPV5, NEC1_NICPL ;  O50258, NLR_DESGI  ;
DR   P13926, SOD1A_XENLA;  P15107, SOD1B_XENLA;  Q3MSU9, SODB_ASPNG ;
DR   O67149, SODC1_AQUAE;  Q42611, SODC1_BRAJU;  O42724, SODC1_DEBHA;
DR   Q55GQ5, SODC1_DICDI;  P93258, SODC1_MESCR;  A2XGP6, SODC1_ORYSI;
DR   Q0DRV6, SODC1_ORYSJ;  E8XDJ8, SODC1_SALT4;  P0CW86, SODC1_SALTY;
DR   P14830, SODC1_SOLLC;  O66602, SODC2_AQUAE;  Q42612, SODC2_BRAJU;
DR   P82902, SODC2_DEBHN;  Q54RN1, SODC2_DICDI;  P11428, SODC2_MAIZE;
DR   O49044, SODC2_MESCR;  P28757, SODC2_ORYSJ;  P29428, SODC2_PICAB;
DR   Q43779, SODC2_SOLLC;  Q54RQ1, SODC3_DICDI;  Q54TU5, SODC4_DICDI;
DR   P23345, SODC4_MAIZE;  Q54G70, SODC5_DICDI;  P23346, SODC5_MAIZE;
DR   Q54TW8, SODC6_DICDI;  O78310, SODCP_ARATH;  O65198, SODCP_MEDSA;
DR   P93407, SODCP_ORYSJ;  P11964, SODCP_PEA  ;  P10792, SODCP_PETHY;
DR   P29427, SODCP_PICAB;  P81082, SODCP_PINPS;  P24707, SODCP_PINSY;
DR   P36214, SODCP_POPTM;  O04997, SODCP_SOLCS;  P14831, SODCP_SOLLC;
DR   P07505, SODCP_SPIOL;  O65199, SODCP_VITVI;  O65175, SODCP_ZANAE;
DR   P24702, SODC_ACTPL ;  Q59081, SODC_AGGAC ;  Q9SQL5, SODC_ANACO ;
DR   P24704, SODC_ARATH ;  Q751L8, SODC_ASHGO ;  Q8X1S6, SODC_ASPFL ;
DR   Q9Y8D9, SODC_ASPFU ;  Q12548, SODC_ASPJA ;  A2QMY6, SODC_ASPNC ;
DR   P85978, SODC_ASPNG ;  Q877B5, SODC_ASPOR ;  P82205, SODC_BOMMO ;
DR   Q52RN5, SODC_BOSMU ;  Q70Q35, SODC_BOTFU ;  P00442, SODC_BOVIN ;
DR   P09678, SODC_BRAOC ;  P15453, SODC_BRUAB ;  P66826, SODC_BRUME ;
DR   P41962, SODC_BRUPA ;  P66827, SODC_BRUSU ;  A8XCP3, SODC_CAEBR ;
DR   P34697, SODC_CAEEL ;  Q8HXP8, SODC_CALJA ;  O59924, SODC_CANAL ;
DR   Q8WNN6, SODC_CANFA ;  Q6FWL5, SODC_CANGA ;  O22373, SODC_CAPAN ;
DR   Q5FB29, SODC_CAPHI ;  P80174, SODC_CARCR ;  O65768, SODC_CARPA ;
DR   P20379, SODC_CAUCR ;  P33431, SODC_CAVPO ;  Q8HXP9, SODC_CEBAP ;
DR   P28755, SODC_CERCA ;  O46412, SODC_CEREL ;  P80566, SODC_CHICK ;
DR   Q07182, SODC_CHYAM ;  Q96VL0, SODC_CLAPU ;  O94178, SODC_COLGL ;
DR   Q8J0N2, SODC_CORMI ;  Q9C0N4, SODC_CRYGA ;  O73872, SODC_DANRE ;
DR   Q9RU48, SODC_DEIRA ;  P54407, SODC_DROBS ;  Q9U4X4, SODC_DROER ;
DR   P61853, SODC_DROMA ;  Q95081, SODC_DROMD ;  P61851, SODC_DROME ;
DR   Q95079, SODC_DROMI ;  Q95085, SODC_DROOB ;  Q9U4X5, SODC_DROOR ;
DR   Q95087, SODC_DROPB ;  Q95088, SODC_DROPE ;  Q95086, SODC_DROPS ;
DR   P61854, SODC_DROSE ;  P61852, SODC_DROSI ;  Q9U4X2, SODC_DROTE ;
DR   Q95095, SODC_DROTO ;  P10791, SODC_DROVI ;  P41973, SODC_DROWI ;
DR   Q9U4X3, SODC_DROYA ;  P0AGD2, SODC_ECO57 ;  P0AGD1, SODC_ECOLI ;
DR   Q9HEY7, SODC_EMENI ;  Q59448, SODC_FRATH ;  Q27666, SODC_HAECO ;
DR   Q59452, SODC_HAEDU ;  P25842, SODC_HAEPA ;  P81926, SODC_HALRO ;
DR   P00443, SODC_HORSE ;  P34936, SODC_HORVU ;  P00441, SODC_HUMAN ;
DR   P83684, SODC_HUMLT ;  Q8HXQ3, SODC_HYLLA ;  Q07796, SODC_IPOBA ;
DR   Q6CPE2, SODC_KLULA ;  P81036, SODC_LAMCR ;  Q5ZT17, SODC_LEGPH ;
DR   P69049, SODC_LEGPN ;  Q8HXQ1, SODC_MACFA ;  Q8HXQ2, SODC_MACFU ;
DR   Q8HXQ0, SODC_MACMU ;  P08228, SODC_MOUSE ;  P0A609, SODC_MYCBO ;
DR   Q9CBI6, SODC_MYCLE ;  Q9AGW2, SODC_MYCPA ;  P0A608, SODC_MYCTU ;
DR   P57005, SODC_NEIMA ;  Q59623, SODC_NEIMB ;  P07509, SODC_NEUCR ;
DR   P27082, SODC_NICPL ;  P24705, SODC_NPVAC ;  O12933, SODC_NPVOP ;
DR   P80740, SODC_OLEEU ;  P24706, SODC_ONCVO ;  Q6T3B0, SODC_PAESI ;
DR   Q8J0N3, SODC_PAETN ;  O22668, SODC_PANGI ;  P60052, SODC_PANTR ;
DR   P83129, SODC_PAROL ;  Q51853, SODC_PASHA ;  Q59689, SODC_PASMU ;
DR   O49073, SODC_PAUKA ;  Q90023, SODC_PBCV1 ;  Q02610, SODC_PEA   ;
DR   P00446, SODC_PHOLE ;  P04178, SODC_PIG   ;  P24669, SODC_PINSY ;
DR   Q711T9, SODC_PODAS ;  Q8HXQ4, SODC_PONPY ;  P11418, SODC_PRIGL ;
DR   P09212, SODC_RABIT ;  P23417, SODC_RANCA ;  P07632, SODC_RAT   ;
DR   O68901, SODC_SALTY ;  Q01137, SODC_SCHMA ;  P28758, SODC_SCHPO ;
DR   P09670, SODC_SHEEP ;  O04996, SODC_SOLCS ;  Q7M1R5, SODC_SOYBN ;
DR   P22233, SODC_SPIOL ;  P81163, SODC_STRHE ;  Q0IIW3, SODC_XENTR ;
DR   P03946, SODC_XIPGL ;  Q6C662, SODC_YARLI ;  P00445, SODC_YEAST ;
DR   O65174, SODC_ZANAE ;  P41963, SODE_BRUPA ;  P34461, SODE_CAEEL ;
DR   P41974, SODE_DIRIM ;  P51547, SODE_HAECO ;  P08294, SODE_HUMAN ;
DR   O09164, SODE_MOUSE ;  Q07449, SODE_ONCVO ;  P41975, SODE_RABIT ;
DR   Q08420, SODE_RAT   ;  P16026, SODE_SCHMA ;  Q9P9L3, SODF_ACIAM ;
DR   Q9Y8H8, SODF_AERPE ;  P83157, SODF_ANASL ;  O67470, SODF_AQUAE ;
DR   Q9X6W9, SODF_AQUPY ;  P21276, SODF_ARATH ;  O15905, SODF_BABBO ;
DR   P53638, SODF_BACFR ;  O35023, SODF_BACSU ;  P37369, SODF_BORPE ;
DR   P53639, SODF_CAMCO ;  Q0PBW9, SODF_CAMJE ;  A1VXQ2, SODF_CAMJJ ;
DR   P19685, SODF_COXBU ;  P83707, SODF_DELAC ;  P0AGD5, SODF_ECO57 ;
DR   P0AGD4, SODF_ECOL6 ;  P0AGD3, SODF_ECOLI ;  P34107, SODF_ENTHI ;
DR   Q9ZKE6, SODF_HELPJ ;  P43312, SODF_HELPY ;  P31108, SODF_LEGPH ;
DR   P23744, SODF_METJ  ;  P18868, SODF_METTH ;  Q60036, SODF_METTM ;
DR   Q7TVI9, SODF_MYCBO ;  P17670, SODF_MYCTU ;  P22302, SODF_NICPL ;
DR   Q8YSZ1, SODF_NOSS1 ;  P81527, SODF_PASPI ;  P09213, SODF_PHOLE ;
DR   Q8IAY6, SODF_PLAF7 ;  Q9TW89, SODF_PLAFA ;  Q27740, SODF_PLAFX ;
DR   Q9Y1B0, SODF_PLAMA ;  Q9Y1A9, SODF_PLAVI ;  P50061, SODF_PLEBO ;
DR   P19665, SODF_PORGI ;  P53641, SODF_PSEAE ;  P84612, SODF_PSEHT ;
DR   Q88PD5, SODF_PSEPK ;  P09223, SODF_PSEPU ;  O93724, SODF_PYRAE ;
DR   Q9XD74, SODF_RHIME ;  O30970, SODF_RHOCA ;  Q1RH88, SODF_RICBR ;
DR   Q92HJ3, SODF_RICCN ;  Q4ULI1, SODF_RICFE ;  Q9ZD15, SODF_RICPR ;
DR   Q68WK0, SODF_RICTY ;  P0A2F5, SODF_SALTI ;  P0A2F4, SODF_SALTY ;
DR   P0AGD6, SODF_SHIFL ;  P28759, SODF_SOYBN ;  O51917, SODF_STRCO ;
DR   Q08713, SODF_SULAC ;  P80857, SODF_SULSO ;  P18655, SODF_SYNE7 ;
DR   P77968, SODF_SYNY3 ;  P19666, SODF_TETPY ;  Q81LW0, SODM1_BACAN;
DR   Q818I1, SODM1_BACCR;  P31161, SODM1_CAEEL;  O08461, SODM1_HALME;
DR   P09737, SODM1_HALSA;  Q03300, SODM1_HALVD;  P09233, SODM1_MAIZE;
DR   P50058, SODM1_PLEBO;  Q2FGH0, SODM1_STAA3;  P0A0J3, SODM1_STAA8;
DR   Q2YT26, SODM1_STAAB;  Q5HFK7, SODM1_STAAC;  P0A0J1, SODM1_STAAM;
DR   P99098, SODM1_STAAN;  Q6GGE6, SODM1_STAAR;  Q6G913, SODM1_STAAS;
DR   P0A0J2, SODM1_STAAW;  Q81JK8, SODM2_BACAN;  Q814I6, SODM2_BACCR;
DR   P41977, SODM2_CAEEL;  O08460, SODM2_HALME;  P09224, SODM2_HALSA;
DR   Q03301, SODM2_HALVD;  P41978, SODM2_MAIZE;  P50059, SODM2_PLEBO;
DR   Q2FKC6, SODM2_STAA3;  Q2G261, SODM2_STAA8;  Q2YUU9, SODM2_STAAB;
DR   Q5HJN5, SODM2_STAAC;  P66830, SODM2_STAAM;  P66831, SODM2_STAAN;
DR   Q6GKH2, SODM2_STAAR;  Q6GCZ1, SODM2_STAAS;  P66832, SODM2_STAAW;
DR   P41979, SODM3_MAIZE;  P50060, SODM3_PLEBO;  P41980, SODM4_MAIZE;
DR   Q59094, SODM_ACIAD ;  Q9P4T6, SODM_AGABI ;  P86254, SODM_ALTAL ;
DR   O81235, SODM_ARATH ;  P83289, SODM_ARTDA ;  Q92450, SODM_ASPFU ;
DR   Q877B6, SODM_ASPOR ;  P28760, SODM_BACCA ;  P83076, SODM_BACCE ;
DR   Q7SIC3, SODM_BACHA ;  Q9KD10, SODM_BACHD ;  P54375, SODM_BACSU ;
DR   O30563, SODM_BORBU ;  P53642, SODM_BORPE ;  P41976, SODM_BOVIN ;
DR   P28761, SODM_BRAFL ;  P57286, SODM_BUCAI ;  Q8K9V4, SODM_BUCAP ;
DR   Q89AR7, SODM_BUCBP ;  Q8HXP0, SODM_CALJA ;  O13401, SODM_CANAL ;
DR   P54712, SODM_CANFA ;  O49066, SODM_CAPAN ;  P49114, SODM_CAVPO ;
DR   Q8HXP1, SODM_CEBAP ;  O96347, SODM_CHAFE ;  Q9PKA0, SODM_CHLMU ;
DR   Q9Z9C4, SODM_CHLPN ;  Q42684, SODM_CHLRE ;  O84296, SODM_CHLTR ;
DR   P42821, SODM_CORDI ;  Q6BQZ1, SODM_DEBHA ;  Q9RUV2, SODM_DEIRA ;
DR   P11419, SODM_DESDE ;  Q55BJ9, SODM_DICDI ;  Q00637, SODM_DROME ;
DR   P66828, SODM_ECO57 ;  P00448, SODM_ECOLI ;  Q838I4, SODM_ENTFA ;
DR   P28762, SODM_EPTST ;  Q92429, SODM_GANMI ;  P00449, SODM_GEOSE ;
DR   Q694A3, SODM_GLOMM ;  O30826, SODM_HAEDU ;  P43725, SODM_HAEIN ;
DR   O08459, SODM_HALHI ;  Q03302, SODM_HALMA ;  P35017, SODM_HEVBR ;
DR   Q9XS41, SODM_HORSE ;  P28524, SODM_HORVU ;  P04179, SODM_HUMAN ;
DR   Q8HXP5, SODM_HYLLA ;  P0A4J1, SODM_LACLA ;  P0A4J2, SODM_LACLM ;
DR   Q92BR6, SODM_LISIN ;  P28763, SODM_LISIV ;  P28764, SODM_LISMO ;
DR   Q8HXP3, SODM_MACFA ;  Q8HXP4, SODM_MACFU ;  Q8HXP2, SODM_MACMU ;
DR   Q5FB30, SODM_MACNE ;  P09671, SODM_MOUSE ;  P47201, SODM_MYCAV ;
DR   P53643, SODM_MYCCE ;  P53644, SODM_MYCCH ;  Q59519, SODM_MYCFO ;
DR   P46728, SODM_MYCIT ;  P50912, SODM_MYCKA ;  P13367, SODM_MYCLE ;
DR   O86165, SODM_MYCLP ;  P53645, SODM_MYCMA ;  P53646, SODM_MYCMR ;
DR   P53647, SODM_MYCPA ;  P53648, SODM_MYCPH ;  A0R652, SODM_MYCS2 ;
DR   P50913, SODM_MYCSC ;  P80582, SODM_MYCSI ;  P53649, SODM_MYCSM ;
DR   P53650, SODM_MYCSZ ;  Q9Y783, SODM_NEUCR ;  P11796, SODM_NICPL ;
DR   P53651, SODM_NOCAS ;  P41981, SODM_ONCVO ;  Q43008, SODM_ORYSJ ;
DR   P28765, SODM_PALVU ;  Q8HXP7, SODM_PANTR ;  P28766, SODM_PARCL ;
DR   Q59679, SODM_PASHA ;  Q9CPN6, SODM_PASMU ;  P27084, SODM_PEA   ;
DR   O75007, SODM_PENCH ;  P28767, SODM_PETMA ;  P28768, SODM_PIG   ;
DR   Q8HXP6, SODM_PONPY ;  P80293, SODM_PROFR ;  Q9SM64, SODM_PRUPE ;
DR   P53652, SODM_PSEAE ;  P77929, SODM_PSEPU ;  P41982, SODM_RABIT ;
DR   P17550, SODM_RALME ;  P36215, SODM_RANCA ;  P22799, SODM_RAOPL ;
DR   P07895, SODM_RAT   ;  Q8Z2V9, SODM_SALTI ;  P43019, SODM_SALTY ;
DR   Q9UQX0, SODM_SCHPO ;  P66829, SODM_SHIFL ;  Q9F326, SODM_STACA ;
DR   Q8VQ15, SODM_STAEP ;  Q5HNZ5, SODM_STAEQ ;  P0C0Q6, SODM_STAES ;
DR   Q4L6Q3, SODM_STAHJ ;  Q49XZ6, SODM_STAS1 ;  Q9K4V3, SODM_STAXY ;
DR   P0A4J3, SODM_STRA3 ;  P0A4J4, SODM_STRA5 ;  P0A4J5, SODM_STRAG ;
DR   O33603, SODM_STRAI ;  O33605, SODM_STRAY ;  O54210, SODM_STRCB ;
DR   P80733, SODM_STRGR ;  O54233, SODM_STRIN ;  O33686, SODM_STRMT ;
DR   P09738, SODM_STRMU ;  O54263, SODM_STROR ;  P0C0I1, SODM_STRP1 ;
DR   P0DF72, SODM_STRP3 ;  Q5XBF8, SODM_STRP6 ;  Q8P0D4, SODM_STRP8 ;
DR   O33756, SODM_STRPA ;  P0A4J6, SODM_STRPN ;  O54266, SODM_STRPO ;
DR   P0DF73, SODM_STRPQ ;  P0C0I0, SODM_STRPY ;  P0A4J7, SODM_STRR6 ;
DR   O33783, SODM_STRSL ;  P53653, SODM_THEAQ ;  P61502, SODM_THET2 ;
DR   P61503, SODM_THET8 ;  P0C0F9, SODM_XANC8 ;  P0C0F8, SODM_XANCP ;
DR   P00447, SODM_YEAST ;  P53655, SODM_YEREN ;  P80735, SODN_STRCO ;
DR   P80732, SODN_STRGR ;  P80734, SODN_STRSO ;
//
ID   1.15.1.2
DE   Superoxide reductase.
AN   Desulfoferrodoxin.
AN   Neelaredoxin.
CA   Reduced rubredoxin + superoxide + 2 H(+) = rubredoxin + H(2)O(2).
CF   Iron.
CC   -!- Formerly EC 1.18.96.1.
DR   Q97GB9, DFX_CLOAB  ;  Q46495, DFX_DESB2  ;  P22076, DFX_DESDA  ;
DR   Q30WF9, DFX_DESDG  ;  P20418, DFX_DESVH  ;  P48345, DFX_DESVM  ;
DR   Q3A221, DFX_PELCD  ;  O29903, SOR_ARCFU  ;  Q58151, SOR_METJA  ;
DR   Q9V098, SOR_PYRAB  ;  P82385, SOR_PYRFU  ;  O58810, SOR_PYRHO  ;
DR   Q5JF09, SOR_PYRKO  ;  Q9WZC6, SOR_THEMA  ;
//
ID   1.16.1.1
DE   Mercury(II) reductase.
AN   Mercuric reductase.
CA   Hg + NADP(+) + H(+) = Hg(2+) + NADPH.
PR   PROSITE; PDOC00073;
DR   Q52109, MERA_ACICA ;  P94188, MERA_ALCSP ;  P16171, MERA_BACCE ;
DR   P94702, MERA_ENTAG ;  P00392, MERA_PSEAE ;  Q51772, MERA_PSEFL ;
DR   P08662, MERA_SERMA ;  Q54465, MERA_SHEPU ;  P08332, MERA_SHIFL ;
DR   P0A0E5, MERA_STAAU ;  P0A0E4, MERA_STAES ;  P30341, MERA_STRLI ;
DR   P17239, MERA_THIFE ;
//
ID   1.16.1.2
DE   Diferric-transferrin reductase.
AN   Transferrin reductase.
CA   Transferrin-[Fe(2+)](2) + NAD(+) = transferrin-[Fe(3+)](2) + NADH.
//
ID   1.16.1.3
DE   Aquacobalamin reductase.
AN   Aquocobalamin reductase.
AN   B(12a) reductase.
AN   NADH-linked aquacobalamin reductase.
AN   NADH:cob(III)alamin oxidoreductase.
AN   Vitamin B(12a) reductase.
CA   2 cob(II)alamin + NAD(+) = 2 aquacob(III)alamin + NADH.
CF   Flavoprotein.
CC   -!- Formerly EC 1.6.99.8.
DR   P0AEN3, FRE_ECO57  ;  P0AEN2, FRE_ECOL6  ;  P0AEN1, FRE_ECOLI  ;
DR   Q9L6L9, FRE_SALTY  ;
//
ID   1.16.1.4
DE   Cob(II)alamin reductase.
AN   B(12r) reductase.
AN   NADH:cob(II)alamin oxidoreductase.
AN   Vitamin B(12r) reductase.
CA   2 cob(I)alamin + NAD(+) = 2 cob(II)alamin + NADH.
CF   Flavoprotein.
CC   -!- Formerly EC 1.6.99.9.
//
ID   1.16.1.5
DE   Aquacobalamin reductase (NADPH).
AN   Aquacobalamin (reduced nicotinamide adenine dinucleotide phosphate)
AN   reductase.
AN   NADPH-linked aquacobalamin reductase.
AN   NADPH:aquacob(III)alamin oxidoreductase.
CA   2 cob(II)alamin + NADP(+) = 2 aquacob(III)alamin + NADPH.
CF   Flavoprotein.
CC   -!- Acts on aquacob(III)alamin and hydroxycobalamin, but not on
CC       cyanocobalamin.
CC   -!- Formerly EC 1.6.99.11.
DR   Q94IN5, PNO_EUGGR  ;
//
ID   1.16.1.6
DE   Cyanocobalamin reductase (cyanide-eliminating).
AN   Cyanocobalamin reductase.
AN   Cyanocobalamin reductase (NADPH, cyanide-eliminating).
AN   Cyanocobalamin reductase (NADPH; CN-eliminating).
AN   NADPH:cyanocob(III)alamin oxidoreductase (cyanide-eliminating).
CA   Cob(I)alamin + cyanide + NADP(+) = cyanocob(III)alamin + NADPH.
CF   Flavoprotein.
CC   -!- Formerly EC 1.6.99.12.
//
ID   1.16.1.7
DE   Ferric-chelate reductase.
AN   Ferric chelate reductase.
AN   Iron chelate reductase.
AN   NADH:Fe(3+) oxidoreductase.
AN   NADH:Fe(3+)-EDTA reductase.
CA   2 Fe(2+) + NAD(+) = 2 Fe(3+) + NADH.
CF   FAD.
CC   -!- Involved in the transport of iron across plant plasma membranes.
CC   -!- Formerly EC 1.6.99.13.
DR   P84468, FERA_PARDE ;  P84469, FERB_PARDE ;  Q75CQ8, FRE8_ASHGO ;
DR   Q12209, FRE8_YEAST ;  P78588, FREL_CANAL ;  Q04800, FRP1_SCHPO ;
//
ID   1.16.1.8
DE   [Methionine synthase] reductase.
AN   [Methionine synthase]-cobalamin methyltransferase (cob(II)alamin
AN   reducing).
AN   Methionine synthase cob(II)alamin reductase (methylating).
AN   Methionine synthase reductase.
CA   2 [methionine synthase]-methylcob(I)alamin + 2 S-adenosylhomocysteine +
CA   NADP(+) = 2 [methionine synthase]-cob(II)alamin + NADPH + 2 S-adenosyl-L-
CA   methionine.
CF   FAD; FMN.
CC   -!- The substrate of the enzyme is the inactivated [Co(II)] form of
CC       EC 2.1.1.13.
CC   -!- Electrons are transferred from NADPH to FAD to FMN.
CC   -!- Formerly EC 2.1.1.135.
DR   Q4JIJ2, MTRR_BOVIN ;  Q17574, MTRR_CAEEL ;  Q9UBK8, MTRR_HUMAN ;
DR   Q8C1A3, MTRR_MOUSE ;  Q498R1, MTRR_RAT   ;
//
ID   1.16.3.1
DE   Ferroxidase.
AN   Ceruloplasmin.
AN   HEPH.
AN   Hephaestin.
CA   4 Fe(2+) + 4 H(+) + O(2) = 4 Fe(3+) + 2 H(2)O.
CF   Copper.
PR   PROSITE; PDOC00076;
DR   P00450, CERU_HUMAN ;  Q61147, CERU_MOUSE ;  P13635, CERU_RAT   ;
DR   Q9XT27, CERU_SHEEP ;  Q9ZR07, FRDA_ARATH ;  Q05B87, FRDA_BOVIN ;
DR   Q9TY03, FRDA_CAEEL ;  Q54C45, FRDA_DICDI ;  Q9W385, FRDA_DROME ;
DR   Q16595, FRDA_HUMAN ;  Q8HXX9, FRDA_MACFA ;  O35943, FRDA_MOUSE ;
DR   D3ZYW7, FRDA_RAT   ;  O74831, FRDA_SCHPO ;  Q07540, FRDA_YEAST ;
DR   Q39101, FRI1_ARATH ;  Q96540, FRI1_BRANA ;  P29036, FRI1_MAIZE ;
DR   P19975, FRI1_PEA   ;  P07229, FRI1_RANCA ;  P19976, FRI1_SOYBN ;
DR   Q8RX97, FRI1_TOBAC ;  Q9SRL5, FRI2_ARATH ;  P29390, FRI2_MAIZE ;
DR   P83445, FRI2_PEA   ;  P07798, FRI2_RANCA ;  Q94IC4, FRI2_SOYBN ;
DR   Q8H1T3, FRI2_TOBAC ;  Q41709, FRI2_VIGUN ;  Q9LYN2, FRI3_ARATH ;
DR   Q948P6, FRI3_SOYBN ;  O65100, FRI3_VIGUN ;  Q9S756, FRI4_ARATH ;
DR   Q948P5, FRI4_SOYBN ;  P25319, FRIH1_SCHMA;  P25320, FRIH2_SCHMA;
DR   Q7SXA6, FRIH3_XENLA;  P49948, FRIHA_XENLA;  P17663, FRIHB_XENLA;
DR   P80145, FRIH_ANAPL ;  O46414, FRIH_BOVIN ;  Q95MP7, FRIH_CANFA ;
DR   P08267, FRIH_CHICK ;  P29389, FRIH_CRIGR ;  O46119, FRIH_ECHGR ;
DR   Q2MHN2, FRIH_FELCA ;  Q8MIP0, FRIH_HORSE ;  P02794, FRIH_HUMAN ;
DR   P09528, FRIH_MOUSE ;  P19130, FRIH_PIG   ;  Q5R8J7, FRIH_PONAB ;
DR   P25915, FRIH_RABIT ;  P19132, FRIH_RAT   ;  P49946, FRIH_SALSA ;
DR   P18685, FRIH_SHEEP ;  P85838, FRIH_TREBE ;  P85837, FRIH_TRENE ;
DR   Q9XT73, FRIH_TRIVU ;  P85836, FRIML_TREBE;  P85839, FRIMS_TREBE;
DR   P49947, FRIM_SALSA ;  P85835, FRIM_TRENE ;  P42577, FRIS_LYMST ;
DR   P42578, FRIY_LYMST ;  P41822, FRI_AEDAE  ;  Q94FY2, FRI_MALXI  ;
DR   Q26061, FRI_PACLE  ;  P25699, FRI_PHAVU  ;  Q2YDI9, FTMT_BOVIN ;
DR   Q8N4E7, FTMT_HUMAN ;  Q9D5H4, FTMT_MOUSE ;  P43707, FTN1_HAEIN ;
DR   P43708, FTN2_HAEIN ;  P0A9A0, FTNA_ECO57 ;  P0A999, FTNA_ECOL6 ;
DR   P0A998, FTNA_ECOLI ;  P0A9A1, FTNA_SHIFL ;  E1WS50, FTN_BACF6  ;
DR   P0CJ83, FTN_BACFR  ;  Q46106, FTN_CAMJE  ;  Q9ZLI1, FTN_HELPJ  ;
DR   P52093, FTN_HELPY  ;  Q2FFK2, FTN_STAA3  ;  Q2FWZ8, FTN_STAA8  ;
DR   Q2YU34, FTN_STAAB  ;  Q5HEN0, FTN_STAAC  ;  Q99SZ3, FTN_STAAM  ;
DR   Q7A4R2, FTN_STAAN  ;  Q6GFG4, FTN_STAAR  ;  Q6G840, FTN_STAAS  ;
DR   Q7A0H5, FTN_STAAW  ;  Q5HN41, FTN_STAEQ  ;  Q8CNP5, FTN_STAES  ;
DR   Q4L7K6, FTN_STAHJ  ;  Q49YT7, FTN_STAS1  ;
//
ID   1.16.5.1
DE   Ascorbate ferrireductase (transmembrane).
AN   Cytochrome b(561).
CA   Ascorbate(Side 1) + Fe(III)(Side 2) = monodehydroascorbate(Side 1) +
CA   Fe(II)(Side 2).
CF   Heme.
CC   -!- A diheme cytochrome that transfers electrons across a single
CC       membrane, such as the outer membrane of the enterocyte, or the
CC       tonoplast membrane of the plant cell vacuole.
CC   -!- Acts on hexacyanoferrate(III) and other ferric chelates.
DR   Q8L856, ACFR1_ARATH;  Q9SWS1, ACFR2_ARATH;  Q67ZF6, ACFR3_ARATH;
DR   Q9C540, ACFR4_ARATH;
//
ID   1.16.8.1
DE   Cob(II)yrinic acid a,c-diamide reductase.
CA   2 cob(I)yrinic acid a,c-diamide + FMN + 2 H(+) = 2 cob(II)yrinic acid
CA   a,c-diamide + FMNH(2).
CC   -!- This enzyme also catalyzes the reduction of cob(II)yric acid,
CC       cob(II)inamide, cob(II)inamide phosphate, GDP-cob(II)inamide and
CC       cob(II)alamin although cob(II)yrinic acid a,c-diamide is thought to
CC       be the physiological substrate.
CC   -!- Also uses FAD and NADH but not NADPH.
DR   P0CY55, BLUB_RHOCA ;  D5AV14, BLUB_RHOCB ;
//
ID   1.16.98.1
DE   Iron:rusticyanin reductase.
CA   Fe(II) + rusticyanin = Fe(III) + reduced rusticyanin.
CF   Heme c.
CC   -!- Contains c-type heme, The enzyme in Acidithiobacillus ferrooxidans is
CC       a component of an electron transfer chain from Fe(II), comprising
CC       this enzyme, the copper protein rusticyanin, cytochrome c4,
CC       and cytochrome c oxidase (EC 1.9.3.1).
//
ID   1.17.1.1
DE   CDP-4-dehydro-6-deoxyglucose reductase.
AN   CDP-4-keto-6-deoxy-D-glucose-3-dehydrogenase system.
AN   CDP-4-keto-6-deoxyglucose reductase.
AN   CDP-4-keto-deoxy-glucose reductase.
AN   Cytidine diphosphate 4-keto-6-deoxy-D-glucose-3-dehydrogenase.
AN   Cytidine diphospho-4-keto-6-deoxy-D-glucose reductase.
AN   NAD(P)H:CDP-4-keto-6-deoxy-D-glucose oxidoreductase.
CA   CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD(P)(+) + H(2)O = CDP-4-dehydro-
CA   6-deoxy-D-glucose + NAD(P)H.
CC   -!- The enzyme consists of two proteins.
CC   -!- One forms an enzyme-bound adduct of the CDP-4-dehydro-6-deoxyglucose
CC       with pyridoxamine phosphate, in which the 3-hydroxy group has been
CC       removed.
CC   -!- The second catalyzes the reduction of this adduct by NAD(P)H and
CC       release of the CDP-4-dehydro-3,6-dideoxy-D-glucose and pyridoxamine
CC       phosphate.
//
ID   1.17.1.2
DE   4-hydroxy-3-methylbut-2-enyl diphosphate reductase.
AN   (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase.
AN   HMBPP reductase.
CA   (1) Isopentenyl diphosphate + NAD(P)(+) + H(2)O = (E)-4-hydroxy-3-
CA   methylbut-2-en-1-yl diphosphate + NAD(P)H.
CA   (2) Dimethylallyl diphosphate + NAD(P)(+) + H(2)O = (E)-4-hydroxy-3-
CA   methylbut-2-en-1-yl diphosphate + NAD(P)H.
CF   Iron-sulfur.
CC   -!- Comprises a system in which ferredoxin is first reduced and
CC       subsequently reoxidized by an NAD(P)(+)-dependent reductase.
CC   -!- This is the last enzyme in the non-mevalonate pathway for isoprenoid
CC       biosynthesis.
CC   -!- Acts in the reverse direction, producing a 5:1 mixture of isopentenyl
CC       diphosphate and dimethyallyl diphosphate.
DR   Q89UU5, ISPH1_BRAJA;  Q629Z7, ISPH1_BURMA;  Q63WH0, ISPH1_BURPS;
DR   P0A5I1, ISPH1_MYCBO;  P0A5I0, ISPH1_MYCTU;  Q6N3G0, ISPH1_RHOPA;
DR   Q89QW7, ISPH2_BRAJA;  Q62HM8, ISPH2_BURMA;  Q9ZFL0, ISPH2_BURPS;
DR   P0A5I3, ISPH2_MYCBO;  P0A5I2, ISPH2_MYCTU;  Q6N1Y1, ISPH2_RHOPA;
DR   B0C4N8, ISPH_ACAM1 ;  Q9RBJ0, ISPH_ACIAD ;  B7GVR1, ISPH_ACIB3 ;
DR   B7IAU0, ISPH_ACIB5 ;  B2HZW3, ISPH_ACIBC ;  B0VQ53, ISPH_ACIBS ;
DR   A3M9H2, ISPH_ACIBT ;  B0V8K4, ISPH_ACIBY ;  A0LW20, ISPH_ACIC1 ;
DR   B7JBD6, ISPH_ACIF2 ;  B5ERJ7, ISPH_ACIF5 ;  A3N2G8, ISPH_ACTP2 ;
DR   B3GYK1, ISPH_ACTP7 ;  B0BRB3, ISPH_ACTPJ ;  A6VQH8, ISPH_ACTSZ ;
DR   A0KG42, ISPH_AERHH ;  A4SIX8, ISPH_AERS4 ;  B9JAQ2, ISPH_AGRRK ;
DR   P58673, ISPH_AGRT5 ;  Q0VSD8, ISPH_ALCBS ;  B6ENC7, ISPH_ALISL ;
DR   A6TRF9, ISPH_ALKMQ ;  A8MFE2, ISPH_ALKOO ;  A7HCQ8, ISPH_ANADF ;
DR   B9KIX9, ISPH_ANAMF ;  Q5PAE7, ISPH_ANAMM ;  B4UEK4, ISPH_ANASK ;
DR   Q3M8X6, ISPH_ANAVT ;  B7GH78, ISPH_ANOFW ;  O67625, ISPH_AQUAE ;
DR   Q5P224, ISPH_AROAE ;  B6YQB8, ISPH_AZOPC ;  A1K4R4, ISPH_AZOSB ;
DR   C1DPH8, ISPH_AZOVD ;  A7Z6T1, ISPH_BACA2 ;  C3P8J4, ISPH_BACAA ;
DR   C3LKW7, ISPH_BACAC ;  A0RIR1, ISPH_BACAH ;  Q81LU9, ISPH_BACAN ;
DR   B7JN13, ISPH_BACC0 ;  Q730P8, ISPH_BACC1 ;  B7IYD9, ISPH_BACC2 ;
DR   C1ESI2, ISPH_BACC3 ;  B7HCR2, ISPH_BACC4 ;  B7HPI8, ISPH_BACC7 ;
DR   A7GSY4, ISPH_BACCN ;  B9IY56, ISPH_BACCQ ;  Q634Q0, ISPH_BACCZ ;
DR   Q5L9K3, ISPH_BACFN ;  Q64PU1, ISPH_BACFR ;  Q9KD37, ISPH_BACHD ;
DR   Q6HDN0, ISPH_BACHK ;  Q65H97, ISPH_BACLD ;  A8FFA1, ISPH_BACP2 ;
DR   Q5WHC6, ISPH_BACSK ;  P54473, ISPH_BACSU ;  Q8A625, ISPH_BACTN ;
DR   A6L1P5, ISPH_BACV8 ;  A9VHR7, ISPH_BACWK ;  A1URX2, ISPH_BARBK ;
DR   Q6G4C5, ISPH_BARHE ;  Q6G0C9, ISPH_BARQU ;  A9IQQ9, ISPH_BART1 ;
DR   Q1LSS7, ISPH_BAUCH ;  B2IED0, ISPH_BEII9 ;  Q8G4L8, ISPH_BIFLO ;
DR   Q493S1, ISPH_BLOPB ;  Q7WHF2, ISPH_BORBR ;  Q7W9B4, ISPH_BORPA ;
DR   Q7VYS2, ISPH_BORPE ;  C0ZL73, ISPH_BREBN ;  B2S9W9, ISPH_BRUA1 ;
DR   Q57EP6, ISPH_BRUAB ;  Q8YFR1, ISPH_BRUME ;  Q8G257, ISPH_BRUSU ;
DR   B8D8U8, ISPH_BUCA5 ;  P57247, ISPH_BUCAI ;  Q8K9Z4, ISPH_BUCAP ;
DR   B8D752, ISPH_BUCAT ;  A7ZCD0, ISPH_CAMC1 ;  A7GXB5, ISPH_CAMC5 ;
DR   A0RQC4, ISPH_CAMFF ;  A7I0N0, ISPH_CAMHC ;  A8FLU3, ISPH_CAMJ8 ;
DR   A7H3F3, ISPH_CAMJD ;  P0C632, ISPH_CAMJE ;  A1VZM8, ISPH_CAMJJ ;
DR   Q5HUR4, ISPH_CAMJR ;  B9KD74, ISPH_CAMLR ;  Q9A345, ISPH_CAUCR ;
DR   Q5L5D3, ISPH_CHLAB ;  Q3AT23, ISPH_CHLCH ;  Q822D9, ISPH_CHLCV ;
DR   Q255J4, ISPH_CHLFF ;  B3EFF5, ISPH_CHLL2 ;  Q9PL59, ISPH_CHLMU ;
DR   B3QQE0, ISPH_CHLP8 ;  B3EM42, ISPH_CHLPB ;  A1BDJ5, ISPH_CHLPD ;
DR   Q9Z6P2, ISPH_CHLPN ;  B0B991, ISPH_CHLT2 ;  B3QSU2, ISPH_CHLT3 ;
DR   Q3KKH8, ISPH_CHLTA ;  B0BAX0, ISPH_CHLTB ;  Q8KFN9, ISPH_CHLTE ;
DR   O84867, ISPH_CHLTR ;  Q1R0B2, ISPH_CHRSD ;  Q7NS59, ISPH_CHRVO ;
DR   A8ALT3, ISPH_CITK8 ;  Q97I09, ISPH_CLOAB ;  Q187C6, ISPH_CLOD6 ;
DR   Q0TRF3, ISPH_CLOP1 ;  P58675, ISPH_CLOPE ;  Q0STT3, ISPH_CLOPS ;
DR   Q895G2, ISPH_CLOTE ;  Q486R1, ISPH_COLP3 ;  Q6NI36, ISPH_CORDI ;
DR   Q8FQP0, ISPH_COREF ;  A4QCY9, ISPH_CORGB ;  Q8NRM2, ISPH_CORGL ;
DR   B1WTZ2, ISPH_CYAA5 ;  B8HWD3, ISPH_CYAP4 ;  B7KEG3, ISPH_CYAP7 ;
DR   B7K4V8, ISPH_CYAP8 ;  Q11YY5, ISPH_CYTH3 ;  Q47BK8, ISPH_DECAR ;
DR   Q3Z6U4, ISPH_DEHE1 ;  A5FPY7, ISPH_DEHSB ;  Q3ZYL6, ISPH_DEHSC ;
DR   Q9RSG0, ISPH_DEIRA ;  B8J3G9, ISPH_DESDA ;  Q316F5, ISPH_DESDG ;
DR   C4XUD2, ISPH_DESMR ;  Q6AL80, ISPH_DESPS ;  Q72G08, ISPH_DESVH ;
DR   B8DMK7, ISPH_DESVM ;  A1VHK1, ISPH_DESVV ;  B5YEC2, ISPH_DICT6 ;
DR   B8E2T7, ISPH_DICTD ;  A8LLC7, ISPH_DINSH ;  A7ZHB8, ISPH_ECO24 ;
DR   B7UI74, ISPH_ECO27 ;  B7MAE9, ISPH_ECO45 ;  B7L4F1, ISPH_ECO55 ;
DR   P62625, ISPH_ECO57 ;  B5YYC1, ISPH_ECO5E ;  B7NHD3, ISPH_ECO7I ;
DR   B7MNN4, ISPH_ECO81 ;  B7M0C5, ISPH_ECO8A ;  C4ZPV5, ISPH_ECOBW ;
DR   B1XBF4, ISPH_ECODH ;  A7ZVX7, ISPH_ECOHS ;  A1A777, ISPH_ECOK1 ;
DR   Q0TLW2, ISPH_ECOL5 ;  P62624, ISPH_ECOL6 ;  B1IRE6, ISPH_ECOLC ;
DR   P62623, ISPH_ECOLI ;  B7N7Q3, ISPH_ECOLU ;  B6HYX7, ISPH_ECOSE ;
DR   B1LFV9, ISPH_ECOSM ;  Q1RGH3, ISPH_ECOUT ;  C5B7M7, ISPH_EDWI9 ;
DR   Q5FFL5, ISPH_EHRRG ;  Q5HB13, ISPH_EHRRW ;  A4W6E4, ISPH_ENT38 ;
DR   A7MIM0, ISPH_ENTS8 ;  Q6D0C6, ISPH_ERWCT ;  B2VH04, ISPH_ERWT9 ;
DR   B7LVN5, ISPH_ESCF3 ;  B1YL84, ISPH_EXIS2 ;  C4L3Z5, ISPH_EXISA ;
DR   B0U064, ISPH_FRAP2 ;  Q14I06, ISPH_FRAT1 ;  A7NA22, ISPH_FRATF ;
DR   Q2A587, ISPH_FRATH ;  B2SES8, ISPH_FRATM ;  A0Q4T9, ISPH_FRATN ;
DR   Q0BNK1, ISPH_FRATO ;  Q5NGK4, ISPH_FRATT ;  A4IYW2, ISPH_FRATW ;
DR   Q8RI52, ISPH_FUSNN ;  B5E9S9, ISPH_GEOBB ;  Q5KX24, ISPH_GEOKA ;
DR   B3E441, ISPH_GEOLS ;  Q39XB6, ISPH_GEOMG ;  B9LZG4, ISPH_GEOSF ;
DR   Q749Y8, ISPH_GEOSL ;  C6E2B3, ISPH_GEOSM ;  C5D4R3, ISPH_GEOSW ;
DR   A4IR05, ISPH_GEOTN ;  A5GE10, ISPH_GEOUR ;  Q7NG74, ISPH_GLOVI ;
DR   Q5FUH7, ISPH_GLUOX ;  Q7VPK4, ISPH_HAEDU ;  Q4QLQ5, ISPH_HAEI8 ;
DR   A5UD69, ISPH_HAEIE ;  A5UID9, ISPH_HAEIG ;  P44976, ISPH_HAEIN ;
DR   B8F6E6, ISPH_HAEPS ;  B0UV08, ISPH_HAES2 ;  Q2S9U2, ISPH_HAHCH ;
DR   C4K4R2, ISPH_HAMD5 ;  Q7VJV5, ISPH_HELHP ;  B6JMP4, ISPH_HELP2 ;
DR   Q1CSL3, ISPH_HELPH ;  P65186, ISPH_HELPJ ;  B2UUG0, ISPH_HELPS ;
DR   P65185, ISPH_HELPY ;  Q0BYQ0, ISPH_HYPNA ;  Q5QZR7, ISPH_IDILO ;
DR   B5Y232, ISPH_KLEP3 ;  A6T4G3, ISPH_KLEP7 ;  C5CIU9, ISPH_KOSOT ;
DR   Q6ADV0, ISPH_LEIXX ;  Q72S57, ISPH_LEPIC ;  Q8F3I3, ISPH_LEPIN ;
DR   C1KV98, ISPH_LISMC ;  Q71ZL9, ISPH_LISMF ;  P58676, ISPH_LISMO ;
DR   B1HTG5, ISPH_LYSSC ;  B9E6U8, ISPH_MACCJ ;  A0LD71, ISPH_MAGSM ;
DR   Q65RQ4, ISPH_MANSM ;  A1TYZ2, ISPH_MARAV ;  Q11KC7, ISPH_MESSB ;
DR   Q607E5, ISPH_METCA ;  A2SJA8, ISPH_METPP ;  B8EQB9, ISPH_METSB ;
DR   B0JVA7, ISPH_MICAN ;  A4T986, ISPH_MYCGI ;  Q9X781, ISPH_MYCLE ;
DR   Q73WH6, ISPH_MYCPA ;  Q8EWR9, ISPH_MYCPE ;  A3Q4N0, ISPH_MYCSJ ;
DR   A1UKL5, ISPH_MYCSK ;  Q1B4H4, ISPH_MYCSS ;  A0PKQ3, ISPH_MYCUA ;
DR   A1TE06, ISPH_MYCVP ;  B9L9K5, ISPH_NAUPA ;  Q5FAF2, ISPH_NEIG1 ;
DR   B4RPZ2, ISPH_NEIG2 ;  A9M1J9, ISPH_NEIM0 ;  P65191, ISPH_NEIMA ;
DR   P65192, ISPH_NEIMB ;  A1KS64, ISPH_NEIMF ;  Q2GDX3, ISPH_NEOSM ;
DR   Q82WM1, ISPH_NITEU ;  A6Q2R7, ISPH_NITSB ;  Q5YQ94, ISPH_NOCFA ;
DR   B2IZV5, ISPH_NOSP7 ;  P58674, ISPH_NOSS1 ;  A6WWG6, ISPH_OCHA4 ;
DR   B1ZXD4, ISPH_OPITP ;  A6LIB3, ISPH_PARD8 ;  A1B842, ISPH_PARDP ;
DR   Q6MC97, ISPH_PARUW ;  P57960, ISPH_PASMU ;  C6DF01, ISPH_PECCP ;
DR   Q3A3D3, ISPH_PELCD ;  Q3B241, ISPH_PELLD ;  B4SCU0, ISPH_PELPB ;
DR   A1ANP9, ISPH_PELPD ;  A9BGS3, ISPH_PETMO ;  B4R8T7, ISPH_PHEZH ;
DR   Q7N8W9, ISPH_PHOLL ;  Q6LUK8, ISPH_PHOPR ;  Q12EY5, ISPH_POLSJ ;
DR   Q7MWK6, ISPH_PORGI ;  B4S4X8, ISPH_PROA2 ;  Q6AA89, ISPH_PROAC ;
DR   A3PAY5, ISPH_PROM0 ;  A2C096, ISPH_PROM1 ;  A2CCK3, ISPH_PROM3 ;
DR   A9BDN6, ISPH_PROM4 ;  A2BUP5, ISPH_PROM5 ;  Q31CR8, ISPH_PROM9 ;
DR   Q7VDS2, ISPH_PROMA ;  B4F2T8, ISPH_PROMH ;  Q7V4T7, ISPH_PROMM ;
DR   Q7V329, ISPH_PROMP ;  A2BP63, ISPH_PROMS ;  Q46HB0, ISPH_PROMT ;
DR   A4SGC0, ISPH_PROVI ;  Q48NK3, ISPH_PSE14 ;  Q15R07, ISPH_PSEA6 ;
DR   B7V0A0, ISPH_PSEA8 ;  Q02GC0, ISPH_PSEAB ;  Q9HVM7, ISPH_PSEAE ;
DR   Q1I4S8, ISPH_PSEE4 ;  Q4K5U7, ISPH_PSEF5 ;  P21864, ISPH_PSEFL ;
DR   C3KDX7, ISPH_PSEFS ;  Q3IE99, ISPH_PSEHT ;  A4XQV8, ISPH_PSEMY ;
DR   A5VY55, ISPH_PSEP1 ;  Q3K6L8, ISPH_PSEPF ;  B0KM87, ISPH_PSEPG ;
DR   Q88Q89, ISPH_PSEPK ;  B1JF80, ISPH_PSEPW ;  Q889E1, ISPH_PSESM ;
DR   Q4ZYJ1, ISPH_PSEU2 ;  Q4FQY8, ISPH_PSYA2 ;  Q1Q974, ISPH_PSYCK ;
DR   A1SZP0, ISPH_PSYIN ;  A5WCZ2, ISPH_PSYWF ;  P58677, ISPH_RALSO ;
DR   B3PSB9, ISPH_RHIE6 ;  Q1MKH8, ISPH_RHIL3 ;  Q985W3, ISPH_RHILO ;
DR   B5ZSV9, ISPH_RHILW ;  Q92RG2, ISPH_RHIME ;  Q7ULU1, ISPH_RHOBA ;
DR   C1A2V7, ISPH_RHOE4 ;  C1AYI4, ISPH_RHOOB ;  A3PGE9, ISPH_RHOS1 ;
DR   Q3J5X0, ISPH_RHOS4 ;  A4WVQ4, ISPH_RHOS5 ;  Q0S489, ISPH_RHOSR ;
DR   Q16AJ6, ISPH_ROSDO ;  A1AXS1, ISPH_RUTMC ;  Q21HK6, ISPH_SACD2 ;
DR   B5F728, ISPH_SALA4 ;  A9MR43, ISPH_SALAR ;  Q57TL2, ISPH_SALCH ;
DR   B5FHE3, ISPH_SALDC ;  B5R1N9, ISPH_SALEP ;  B5RG84, ISPH_SALG2 ;
DR   B4TIE9, ISPH_SALHS ;  B4T6H5, ISPH_SALNS ;  Q5PKI4, ISPH_SALPA ;
DR   A9MYG8, ISPH_SALPB ;  C0Q4I9, ISPH_SALPC ;  B5BLL3, ISPH_SALPK ;
DR   B4TWP0, ISPH_SALSV ;  P58678, ISPH_SALTI ;  P58679, ISPH_SALTY ;
DR   A8G9L7, ISPH_SERP5 ;  B0TJB2, ISPH_SHEHH ;  Q8EBI7, ISPH_SHEON ;
DR   A8H1H6, ISPH_SHEPA ;  B2U248, ISPH_SHIB3 ;  Q326J4, ISPH_SHIBS ;
DR   Q32K68, ISPH_SHIDS ;  Q0T8G5, ISPH_SHIF8 ;  Q7UDT8, ISPH_SHIFL ;
DR   Q3Z5Y1, ISPH_SHISS ;  Q5LNJ7, ISPH_SILPO ;  Q1GDG5, ISPH_SILST ;
DR   Q2NVY3, ISPH_SODGM ;  Q82IE8, ISPH_STRAW ;  Q9FBM1, ISPH_STRCO ;
DR   B1W2D7, ISPH_STRGG ;  B4SP20, ISPH_STRM5 ;  B2FU83, ISPH_STRMK ;
DR   Q30S81, ISPH_SULDN ;  A6Q7P9, ISPH_SULNB ;  Q67QZ8, ISPH_SYMTH ;
DR   Q31S64, ISPH_SYNE7 ;  B1XPG7, ISPH_SYNP2 ;  Q5N249, ISPH_SYNP6 ;
DR   A5GIF7, ISPH_SYNPW ;  Q7U9K4, ISPH_SYNPX ;  A5GWG3, ISPH_SYNR3 ;
DR   Q0IDE5, ISPH_SYNS3 ;  Q3B080, ISPH_SYNS9 ;  Q3AN10, ISPH_SYNSC ;
DR   Q55643, ISPH_SYNY3 ;  Q8DK29, ISPH_THEEB ;  A8F7S0, ISPH_THELT ;
DR   Q9X1F7, ISPH_THEMA ;  B9K8E2, ISPH_THENN ;  A5IME1, ISPH_THEP1 ;
DR   B0K9L0, ISPH_THEP3 ;  B0K197, ISPH_THEPX ;  B1LBI2, ISPH_THESQ ;
DR   Q72G65, ISPH_THET2 ;  Q5SMC8, ISPH_THET8 ;  Q8RA76, ISPH_THETN ;
DR   B8GQR4, ISPH_THISH ;  C4LD10, ISPH_TOLAT ;  Q73NQ6, ISPH_TREDE ;
DR   O83558, ISPH_TREPA ;  B2S3D9, ISPH_TREPS ;  Q10WA8, ISPH_TRIEI ;
DR   Q83NB2, ISPH_TROW8 ;  Q83MR9, ISPH_TROWT ;  A5CVK1, ISPH_VESOH ;
DR   Q9KU44, ISPH_VIBCH ;  Q5E7N1, ISPH_VIBF1 ;  B5FA63, ISPH_VIBFM ;
DR   Q87S87, ISPH_VIBPA ;  Q8DET0, ISPH_VIBVU ;  Q7MNM5, ISPH_VIBVY ;
DR   Q8D2R2, ISPH_WIGBR ;  Q73FQ1, ISPH_WOLPM ;  B3CM01, ISPH_WOLPP ;
DR   Q7M8Y6, ISPH_WOLSU ;  Q5GTN6, ISPH_WOLTR ;  C0R4T5, ISPH_WOLWR ;
DR   Q8PN17, ISPH_XANAC ;  Q3BW40, ISPH_XANC5 ;  Q4US42, ISPH_XANC8 ;
DR   B0RY26, ISPH_XANCB ;  Q8PBG4, ISPH_XANCP ;  Q2P5A8, ISPH_XANOM ;
DR   B2STC6, ISPH_XANOP ;  Q5H2D9, ISPH_XANOR ;  B2I6V0, ISPH_XYLF2 ;
DR   P65193, ISPH_XYLFA ;  B0U3Q7, ISPH_XYLFM ;  P65194, ISPH_XYLFT ;
DR   A1JJE4, ISPH_YERE8 ;  A7FMD4, ISPH_YERP3 ;  Q1C0J0, ISPH_YERPA ;
DR   B2K3M9, ISPH_YERPB ;  P58680, ISPH_YERPE ;  A9R005, ISPH_YERPG ;
DR   Q1CMU8, ISPH_YERPN ;  A4TQF0, ISPH_YERPP ;  Q66ES1, ISPH_YERPS ;
DR   B1JKZ5, ISPH_YERPY ;  Q5NP61, ISPH_ZYMMO ;
//
ID   1.17.1.3
DE   Leucoanthocyanidin reductase.
AN   Leucocyanidin reductase.
CA   (2R,3S)-catechin + NADP(+) + H(2)O = 2,3-trans-3,4-cis-leucocyanidin +
CA   NADPH.
CC   -!- Catalyzes the synthesis of catechin, catechin-4-beta-ol
CC       (leucocyanidin) and the related flavan-3-ols afzelechin and
CC       gallocatechin, which are initiating monomers in the synthesis of
CC       plant polymeric proanthocyanidins or condensed tannins.
CC   -!- While 2,3-trans-3,4-cis-leucocyanidin is the preferred flavan-3,4-
CC       diol substrate, 2,3-trans-3,4-cis-leucodelphinidin and 2,3-trans-3,
CC       4-cis-leucopelargonidin can also act as substrates, but more slowly.
CC   -!- NADH can replace NADPH but is oxidized more slowly.
DR   Q84V83, LAR_DESUN  ;
//
ID   1.17.1.4
DE   Xanthine dehydrogenase.
AN   NAD-xanthine dehydrogenase.
AN   Xanthine oxidoreductase.
AN   Xanthine-NAD oxidoreductase.
AN   Xanthine/NAD(+) oxidoreductase.
CA   (1) Xanthine + NAD(+) + H(2)O = urate + NADH.
CA   (2) Hypoxanthine + NAD(+) + H(2)O = xanthine + NADH.
CF   FAD; Iron-sulfur; Molybdenum.
CC   -!- Acts on a variety of purines and aldehydes, including hypoxanthine.
CC   -!- The animal enzyme can be interconverted to EC 1.17.3.2 (the oxidase
CC       form).
CC   -!- That from liver exists in vivo mainly in the dehydrogenase form,
CC       but can be converted into EC 1.17.3.2 by storage at -20 degrees
CC       Celsius, by treatment with proteolytic agents or organic solvents,
CC       or by thiol reagents such as Cu(2+), N-ethylmaleamide or
CC       4-hydroxymercuribenzoate.
CC   -!- The effect of thiol reagents can be reversed by thiols such as 1,4-
CC       dithioerythritol.
CC   -!- This enzyme can also be converted into EC 1.17.3.2 by EC 1.8.4.7 in
CC       the presence of glutathione disulfide.
CC   -!- In other animal tissues, the enzyme exists almost entirely as
CC       EC 1.17.3.2, but can be converted into the dehydrogenase form by 1,4-
CC       dithioerythritol.
CC   -!- Formerly EC 1.2.1.37 and EC 1.1.1.204.
PR   PROSITE; PDOC00484;
DR   O32147, XDHA_BACSU ;  Q8X6C7, XDHA_ECO57 ;  Q46799, XDHA_ECOLI ;
DR   Q8X6C5, XDHB_ECO57 ;  Q46800, XDHB_ECOLI ;  O32145, XDHC_BACSU ;
DR   O32144, XDHD_BACSU ;  O32143, XDHE_BACSU ;  P80457, XDH_BOVIN  ;
DR   P08793, XDH_CALVI  ;  P47990, XDH_CHICK  ;  Q54FB7, XDH_DICDI  ;
DR   P10351, XDH_DROME  ;  P22811, XDH_DROPS  ;  P91711, XDH_DROSU  ;
DR   Q12553, XDH_EMENI  ;  Q9MYW6, XDH_FELCA  ;  P47989, XDH_HUMAN  ;
DR   Q00519, XDH_MOUSE  ;  P22985, XDH_RAT    ;  Q8X6J4, YAGR_ECO57 ;
DR   P77489, YAGR_ECOLI ;  Q8X6J0, YAGS_ECO57 ;  P77324, YAGS_ECOLI ;
//
ID   1.17.1.5
DE   Nicotinate dehydrogenase.
AN   Nicotinate hydroxylase.
AN   Nicotinic acid hydroxylase.
CA   Nicotinate + H(2)O + NADP(+) = 6-hydroxynicotinate + NADPH.
CF   Flavoprotein; Iron.
CC   -!- The enzyme is capable of acting on a variety of nicotinate analogs to
CC       varying degrees, including pyrazine-2-carboxylate, pyrazine 2,3-
CC       dicarboxylate, trigonelline and 6-methylnicotinate.
CC   -!- The enzyme from Clostridium barkeri also possesses a catalytically
CC       essential, labile selenium that can be removed by reaction with
CC       cyanide.
CC   -!- Forms part of the nicotinate-fermentation catabolism pathway in
CC       Eubacterium barkeri.
CC   -!- Other enzymes involved in this pathway are EC 1.3.7.1, EC 3.5.2.18,
CC       EC 1.1.1.291, EC 5.4.99.4, EC 5.3.3.6, EC 4.2.1.85 and EC 4.1.3.32.
CC   -!- Formerly EC 1.5.1.13.
DR   Q0QLF4, NDFS_EUBBA ;  Q0QLF2, NDLMS_EUBBA;  Q0QLF1, NDMMS_EUBBA;
DR   Q0QLF3, NDSFS_EUBBA;
//
ID   1.17.1.6
DE   Transferred entry: 1.17.99.5.
//
ID   1.17.2.1
DE   Nicotinate dehydrogenase (cytochrome).
AN   Nicotinate hydroxylase.
AN   Nicotinic acid hydroxylase.
CA   Nicotinate + a ferricytochrome + H(2)O = 6-hydroxynicotinate +
CA   a ferrocytochrome.
CF   Iron-sulfur; Molybdopterin cytosine dinucleotide.
CC   -!- This two-component enzyme from Pseudomonas belongs to the family of
CC       xanthine dehydrogenases, but differs from most other members of this
CC       family.
CC   -!- While most members contain an FAD cofactor, the large subunit of this
CC       enzyme contains three c-type cytochromes, enabling it to interact
CC       with the electron transfer chain, probably by delivering the
CC       electrons to a cytochrome oxidase.
//
ID   1.17.3.1
DE   Pteridine oxidase.
CA   2-amino-4-hydroxypteridine + O(2) = 2-amino-4,7-dihydroxypteridine + (?).
CC   -!- Does not act on hypoxanthine.
CC   -!- Different from EC 1.17.3.2.
//
ID   1.17.3.2
DE   Xanthine oxidase.
AN   Hypoxanthine oxidase.
AN   Hypoxanthine-xanthine oxidase.
AN   Hypoxanthine:oxygen oxidoreductase.
AN   Schardinger enzyme.
AN   Xanthine oxidoreductase.
AN   Xanthine:O(2) oxidoreductase.
AN   Xanthine:xanthine oxidase.
CA   Xanthine + H(2)O + O(2) = urate + H(2)O(2).
CF   FAD; Iron-sulfur; Molybdopterin.
CC   -!- Also oxidizes hypoxanthine, some other purines and pterins,
CC       and aldehydes (i.e. possesses the activity of EC 1.2.3.1).
CC   -!- Under some conditions the product is mainly superoxide rather than
CC       peroxide: R-H + H(2)O + 2 O(2) = ROH + 2 O(2)(.-) + 2 H(+).
CC   -!- The enzyme from animal tissues can be converted into EC 1.17.1.4.
CC   -!- That from liver exists in vivo mainly as the dehydrogenase form,
CC       but can be converted into the oxidase form by storage at -20 degrees
CC       Celsius, by treatment with proteolytic enzymes or with organic
CC       solvents, or by thiol reagents such as Cu(2+), N-ethylmaleamide or
CC       4-mercuribenzoate.
CC   -!- The effect of thiol reagents can be reversed by thiols such as 1,4-
CC       dithioerythritol.
CC   -!- EC 1.17.1.4 can also be converted into this enzyme by EC 1.8.4.7 in
CC       the presence of glutathione disulfide.
CC   -!- The Micrococcus enzyme can use ferredoxin as acceptor.
CC   -!- Formerly EC 1.1.3.22 and EC 1.2.3.2.
PR   PROSITE; PDOC00484;
DR   P80457, XDH_BOVIN  ;  P47990, XDH_CHICK  ;  Q9MYW6, XDH_FELCA  ;
DR   P47989, XDH_HUMAN  ;  Q00519, XDH_MOUSE  ;  P22985, XDH_RAT    ;
//
ID   1.17.3.3
DE   6-hydroxynicotinate dehydrogenase.
AN   6-hydroxynicotinate hydroxylase.
AN   6-hydroxynicotinic acid dehydrogenase.
AN   6-hydroxynicotinic acid hydroxylase.
CA   6-hydroxynicotinate + H(2)O + O(2) = 2,6-dihydroxynicotinate + H(2)O(2).
CF   FAD; Iron-sulfur; Molybdopterin.
CC   -!- The enzyme also has a catalytically essential, labile selenium that
CC       can be removed by reaction with cyanide.
CC   -!- In Bacillus niacini, this enzyme is required for growth on nicotinic
CC       acid.
//
ID   1.17.4.1
DE   Ribonucleoside-diphosphate reductase.
AN   Ribonucleotide reductase.
CA   2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H(2)O =
CA   ribonucleoside diphosphate + thioredoxin.
CF   Iron.
CC   -!- Responsible for the de novo conversion of ribonucleoside diphosphates
CC       into deoxyribonucleoside diphosphates, which are essential for DNA
CC       synthesis and repair.
CC   -!- While the enzyme is activated by ATP, it is inhibited by dATP.
PR   PROSITE; PDOC00084;
PR   PROSITE; PDOC00317;
DR   O64174, BNRDF_BPSPB;  O31875, NRDEB_BACSU;  O64173, NRDEB_BPSPB;
DR   Q8UEM4, NRDJ_AGRT5 ;  Q6MNP6, NRDJ_BDEBA ;  Q89MB9, NRDJ_BRAJA ;
DR   Q72S00, NRDJ_LEPIC ;  Q8F3P1, NRDJ_LEPIN ;  Q7UI46, NRDJ_RHOBA ;
DR   Q82KE2, NRDJ_STRAW ;  O54196, NRDJ_STRCL ;  O69981, NRDJ_STRCO ;
DR   Q9XD73, NRDJ_STRCT ;  O53767, NRDZ_MYCTU ;  P0CG99, RIR1A_MYCS2;
DR   P0CH00, RIR1B_MYCS2;  O36411, RIR1_ALHV1 ;  O66503, RIR1_AQUAE ;
DR   Q9SJ20, RIR1_ARATH ;  P42491, RIR1_ASFB7 ;  P0C8H7, RIR1_ASFK5 ;
DR   P26685, RIR1_ASFM2 ;  P0C8H8, RIR1_ASFP4 ;  P0C8H9, RIR1_ASFWA ;
DR   P50620, RIR1_BACSU ;  P50646, RIR1_BHV1C ;  P32282, RIR1_BPT4  ;
DR   P57276, RIR1_BUCAI ;  Q8K9W3, RIR1_BUCAP ;  Q89AS4, RIR1_BUCBP ;
DR   Q03604, RIR1_CAEEL ;  Q9PL93, RIR1_CHLMU ;  Q9Z6S5, RIR1_CHLPN ;
DR   O84834, RIR1_CHLTR ;  O61065, RIR1_CRYPV ;  P79732, RIR1_DANRE ;
DR   Q54Q71, RIR1_DICDI ;  P48591, RIR1_DROME ;  P0C702, RIR1_EBVA8 ;
DR   P03190, RIR1_EBVB9 ;  Q3KSU5, RIR1_EBVG  ;  P00452, RIR1_ECOLI ;
DR   P28846, RIR1_EHV1B ;  Q66663, RIR1_EHV2  ;  P50642, RIR1_EHV4  ;
DR   Q8SR37, RIR1_ENCCU ;  Q6GZT8, RIR1_FRG3G ;  Q77MS1, RIR1_GAHVM ;
DR   P43754, RIR1_HAEIN ;  Q9ZLF9, RIR1_HELPJ ;  P55982, RIR1_HELPY ;
DR   P08543, RIR1_HHV11 ;  P09853, RIR1_HHV23 ;  P89462, RIR1_HHV2H ;
DR   P23921, RIR1_HUMAN ;  Q196Z5, RIR1_IIV3  ;  O55716, RIR1_IIV6  ;
DR   Q7T6Y8, RIR1_MIMIV ;  P07742, RIR1_MOUSE ;  P0A5W9, RIR1_MYCBO ;
DR   P47473, RIR1_MYCGE ;  Q9CBQ0, RIR1_MYCLE ;  P78027, RIR1_MYCPN ;
DR   P0A5W8, RIR1_MYCTU ;  Q9UW15, RIR1_NEUCR ;  Q6R7H4, RIR1_OSHVF ;
DR   P50648, RIR1_PLAF4 ;  P50647, RIR1_PLAFG ;  Q5R919, RIR1_PONAB ;
DR   Q6UDJ2, RIR1_PSHV1 ;  P37426, RIR1_SALTY ;  P36602, RIR1_SCHPO ;
DR   Q01037, RIR1_SHV21 ;  P50643, RIR1_SUHVK ;  P74240, RIR1_SYNY3 ;
DR   O83972, RIR1_TREPA ;  O15909, RIR1_TRYBB ;  Q76RD8, RIR1_VACCA ;
DR   P20503, RIR1_VACCC ;  P12848, RIR1_VACCW ;  P32984, RIR1_VAR67 ;
DR   P09248, RIR1_VZVD  ;  Q4JQV6, RIR1_VZVO  ;  P21524, RIR1_YEAST ;
DR   P50651, RIR2A_ARATH;  Q10840, RIR2A_MYCTU;  Q6Y657, RIR2B_ARATH;
DR   Q7LG56, RIR2B_HUMAN;  Q4R741, RIR2B_MACFA;  Q6PEE3, RIR2B_MOUSE;
DR   Q50549, RIR2B_MYCTU;  Q5R9G0, RIR2B_PONAB;  Q9LSD0, RIR2C_ARATH;
DR   O36410, RIR2_ALHV1 ;  O67475, RIR2_AQUAE ;  P42492, RIR2_ASFB7 ;
DR   P0C8I0, RIR2_ASFK5 ;  P26713, RIR2_ASFM2 ;  P0C8I1, RIR2_ASFP4 ;
DR   P0C8I2, RIR2_ASFWA ;  Q9KFH7, RIR2_BACHD ;  P50621, RIR2_BACSU ;
DR   Q01319, RIR2_BHV1C ;  P11156, RIR2_BPT4  ;  P57275, RIR2_BUCAI ;
DR   Q8K9W4, RIR2_BUCAP ;  Q89AS5, RIR2_BUCBP ;  P42170, RIR2_CAEEL ;
DR   Q9PL92, RIR2_CHLMU ;  Q9Z6S4, RIR2_CHLPN ;  O84835, RIR2_CHLTR ;
DR   P79733, RIR2_DANRE ;  P42521, RIR2_DICDI ;  P48592, RIR2_DROME ;
DR   P0CAP7, RIR2_EBVA8 ;  P0CAP6, RIR2_EBVB9 ;  P0C701, RIR2_EBVG  ;
DR   P69925, RIR2_ECO57 ;  P69924, RIR2_ECOLI ;  P28847, RIR2_EHV1B ;
DR   Q66662, RIR2_EHV2  ;  P50644, RIR2_EHV4  ;  Q8SRR2, RIR2_ENCCU ;
DR   Q6GZQ8, RIR2_FRG3G ;  Q77MS0, RIR2_GAHVM ;  P43755, RIR2_HAEIN ;
DR   Q9ZKC3, RIR2_HELPJ ;  P55983, RIR2_HELPY ;  P10224, RIR2_HHV11 ;
DR   P06474, RIR2_HHV1K ;  P69520, RIR2_HHV23 ;  P69521, RIR2_HHV2H ;
DR   P31350, RIR2_HUMAN ;  Q197B2, RIR2_IIV3  ;  Q91FE8, RIR2_IIV6  ;
DR   O46310, RIR2_LEIAM ;  Q4R7Q7, RIR2_MACFA ;  Q60561, RIR2_MESAU ;
DR   Q7T6Y9, RIR2_MIMIV ;  P11157, RIR2_MOUSE ;  Q9XC20, RIR2_MYCGA ;
DR   P47471, RIR2_MYCGE ;  Q9CBQ2, RIR2_MYCLE ;  P75461, RIR2_MYCPN ;
DR   Q9C167, RIR2_NEUCR ;  Q6R7K3, RIR2_OSHVF ;  P50650, RIR2_PLAF4 ;
DR   P50649, RIR2_PLAFG ;  Q6UDJ1, RIR2_PSHV1 ;  Q4KLN6, RIR2_RAT   ;
DR   Q9QTF2, RIR2_RSIV  ;  P37427, RIR2_SALTY ;  P36603, RIR2_SCHPO ;
DR   Q01038, RIR2_SHV21 ;  P07201, RIR2_SPISO ;  P50645, RIR2_SUHVK ;
DR   P32209, RIR2_SWPVK ;  P49730, RIR2_TOBAC ;  O83092, RIR2_TREPA ;
DR   O15910, RIR2_TRYBB ;  O57175, RIR2_VACCA ;  P20493, RIR2_VACCC ;
DR   P29883, RIR2_VACCP ;  P11158, RIR2_VACCW ;  P33799, RIR2_VAR67 ;
DR   P09247, RIR2_VZVD  ;  Q4JQV7, RIR2_VZVO  ;  P09938, RIR2_YEAST ;
DR   Q9DHU2, RIR2_YLDV  ;  P39452, RIR3_ECOLI ;  Q08698, RIR3_SALTY ;
DR   P21672, RIR3_YEAST ;  P37146, RIR4_ECOLI ;  P17424, RIR4_SALTY ;
DR   P49723, RIR4_YEAST ;  O30601, YOSP_BACSU ;
//
ID   1.17.4.2
DE   Ribonucleoside-triphosphate reductase.
AN   Ribonucleotide reductase.
CA   2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H(2)O =
CA   ribonucleoside triphosphate + thioredoxin.
CF   Cobalt.
PR   PROSITE; PDOC00665;
DR   P07071, NRDD_BPT4  ;  P28903, NRDD_ECOLI ;  P43752, NRDD_HAEIN ;
DR   Q9L646, NRDD_SALTY ;  Q54CW7, RTPR_DICDI ;  Q2PDF6, RTPR_EUGGR ;
DR   Q5FMX8, RTPR_LACAC ;  Q03PB4, RTPR_LACBA ;  Q035U1, RTPR_LACC3 ;
DR   Q1G7W2, RTPR_LACDA ;  Q04CQ7, RTPR_LACDB ;  Q041L3, RTPR_LACGA ;
DR   A8YW74, RTPR_LACH4 ;  Q59490, RTPR_LACLE ;  A6Q367, RTPR_NITSB ;
DR   Q857H2, VG50_BPMB2 ;  O64240, VG50_BPMD2 ;  Q05262, VG50_BPML5 ;
//
ID   1.17.4.3
DE   Transferred entry: 1.17.7.1.
//
ID   1.17.5.1
DE   Phenylacetyl-CoA dehydrogenase.
AN   Phenylacetyl-CoA:acceptor oxidoreductase.
CA   Phenylacetyl-CoA + H(2)O + 2 quinone = phenylglyoxylyl-CoA + 2 quinol.
CF   Iron-sulfur; Molybdopterin.
CC   -!- The enzyme is specific for phenylacetyl-CoA as substrate.
CC   -!- Phenylacetate, acetyl-CoA, benzoyl-CoA, propanoyl-CoA, crotonyl-CoA,
CC       succinyl-CoA and 3-hydroxybenzoyl-CoA cannot act as substrates.
CC   -!- The oxygen atom introduced into the product, phenylglyoxylyl-CoA,
CC       is derived from water and not molecular oxygen.
CC   -!- Duroquinone, menaquinone and 2,6-dichlorophenolindophenol (DCPIP) can
CC       act as acceptor, but the likely physiological acceptor is ubiquinone.
CC   -!- A second enzyme, EC 3.1.2.25 converts the phenylglyoxylyl-CoA formed
CC       into phenylglyoxylate.
//
ID   1.17.5.2
DE   Caffeine dehydrogenase.
CA   Caffeine + ubiquinone + H(2)O = 1,3,7-trimethylurate + ubiquinol.
CC   -!- This enzyme, characterized from the soil bacterium Pseudomonas sp.
CC       CBB1, catalyzes the incorporation of an oxygen atom originating from
CC       a water molecule into position C-8 of caffeine.
CC   -!- The enzyme utilizes short-tail ubiquinones as the preferred electron
CC       acceptor.
//
ID   1.17.7.1
DE   (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase.
AN   (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase.
AN   4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase.
CA   (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H(2)O + 2 oxidized
CA   ferredoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + 2 reduced
CA   ferredoxin.
CF   Iron-sulfur.
CC   -!- Forms, in the reverse direction, part of an alternative non-
CC       mevalonate pathway for isoprenoid biosynthesis that is found in most
CC       bacteria and in plant chloroplasts.
CC   -!- The enzyme from the plant Arabidopsis thaliana is active with
CC       photoreduced 5-deazaflavin but not with the flavodoxin/flavodoxin
CC       reductase/NADPH system that can be used as an electron donor by
CC       Escherichia coli.
CC   -!- Metabolites derived from isoprenoids play important roles in systems
CC       such as electron transport, photosynthesis, plant defense responses,
CC       hormonal regulation of development and membrane fluidity.
CC   -!- Formerly EC 1.17.4.3.
DR   Q82K43, ISPG1_STRAW;  Q9X7W2, ISPG1_STRCO;  Q82ML3, ISPG2_STRAW;
DR   Q9KYR9, ISPG2_STRCO;  B0C6E1, ISPG_ACAM1 ;  Q6FEM3, ISPG_ACIAD ;
DR   B7H069, ISPG_ACIB3 ;  B7I5G7, ISPG_ACIB5 ;  B2I3E5, ISPG_ACIBC ;
DR   Q1IRS5, ISPG_ACIBL ;  B0VKR8, ISPG_ACIBS ;  A3M211, ISPG_ACIBT ;
DR   B0V5G7, ISPG_ACIBY ;  A0LV34, ISPG_ACIC1 ;  A5FX97, ISPG_ACICJ ;
DR   B7JC30, ISPG_ACIF2 ;  B5EJF3, ISPG_ACIF5 ;  A3N1H8, ISPG_ACTP2 ;
DR   B3GY64, ISPG_ACTP7 ;  B0BQB9, ISPG_ACTPJ ;  A6VQX6, ISPG_ACTSZ ;
DR   B9JE02, ISPG_AGRRK ;  P58665, ISPG_AGRT5 ;  B9JV07, ISPG_AGRVS ;
DR   B2UKT9, ISPG_AKKM8 ;  Q0VNE0, ISPG_ALCBS ;  B6EGY7, ISPG_ALISL ;
DR   B4RV89, ISPG_ALTMD ;  Q5PAJ1, ISPG_ANAMM ;  Q3MG27, ISPG_ANAVT ;
DR   B7GH89, ISPG_ANOFW ;  O67496, ISPG_AQUAE ;  Q5P7B3, ISPG_AROAE ;
DR   A1R501, ISPG_ARTAT ;  B8HG44, ISPG_ARTCA ;  A0JUS8, ISPG_ARTS2 ;
DR   C1DE57, ISPG_AZOVD ;  A7Z6S2, ISPG_BACA2 ;  C3P8I5, ISPG_BACAA ;
DR   C3LKV7, ISPG_BACAC ;  A0RIQ2, ISPG_BACAH ;  Q81LV7, ISPG_BACAN ;
DR   B7JN03, ISPG_BACC0 ;  Q730Q8, ISPG_BACC1 ;  B7IYD0, ISPG_BACC2 ;
DR   C1ES01, ISPG_BACC3 ;  B7HCQ3, ISPG_BACC4 ;  B7HPH8, ISPG_BACC7 ;
DR   A7GSX5, ISPG_BACCN ;  B9IY45, ISPG_BACCQ ;  Q818H8, ISPG_BACCR ;
DR   Q634Q9, ISPG_BACCZ ;  Q5L7W2, ISPG_BACFN ;  Q64N34, ISPG_BACFR ;
DR   Q9KD18, ISPG_BACHD ;  Q6HDN9, ISPG_BACHK ;  Q65HA9, ISPG_BACLD ;
DR   A8FF87, ISPG_BACP2 ;  Q5WHB2, ISPG_BACSK ;  P54482, ISPG_BACSU ;
DR   Q8A4T0, ISPG_BACTN ;  A6L089, ISPG_BACV8 ;  A9VH61, ISPG_BACWK ;
DR   A1UR54, ISPG_BARBK ;  Q6G1X4, ISPG_BARHE ;  Q6G104, ISPG_BARQU ;
DR   A9IYW1, ISPG_BART1 ;  Q1LU77, ISPG_BAUCH ;  B2IE63, ISPG_BEII9 ;
DR   Q8G7Y6, ISPG_BIFLO ;  Q492E0, ISPG_BLOPB ;  Q7WHN0, ISPG_BORBR ;
DR   Q7W6P6, ISPG_BORPA ;  Q7VWL0, ISPG_BORPE ;  Q89VV9, ISPG_BRAJA ;
DR   A5ETI5, ISPG_BRASB ;  A4YKQ8, ISPG_BRASO ;  C0ZF58, ISPG_BREBN ;
DR   B2S7K6, ISPG_BRUA1 ;  Q2YLG4, ISPG_BRUA2 ;  Q57BA5, ISPG_BRUAB ;
DR   A9M820, ISPG_BRUC2 ;  C0RF32, ISPG_BRUMB ;  Q8YJ17, ISPG_BRUME ;
DR   A9WWQ2, ISPG_BRUSI ;  Q8FYT2, ISPG_BRUSU ;  P57374, ISPG_BUCAI ;
DR   Q8K9P4, ISPG_BUCAP ;  B1YR44, ISPG_BURA4 ;  B4EAW9, ISPG_BURCJ ;
DR   A3MK75, ISPG_BURM7 ;  A2S2A2, ISPG_BURM9 ;  Q62JW4, ISPG_BURMA ;
DR   A1V4K1, ISPG_BURMS ;  A3NVX1, ISPG_BURP0 ;  Q3JRQ3, ISPG_BURP1 ;
DR   A3NA54, ISPG_BURP6 ;  Q63UT3, ISPG_BURPS ;  A4XLZ4, ISPG_CALS8 ;
DR   A7ZCT9, ISPG_CAMC1 ;  A7GZ54, ISPG_CAMC5 ;  A0RPL8, ISPG_CAMFF ;
DR   A8FLB6, ISPG_CAMJ8 ;  A7H4D8, ISPG_CAMJD ;  Q9PPM1, ISPG_CAMJE ;
DR   A1VZ41, ISPG_CAMJJ ;  Q5HV95, ISPG_CAMJR ;  B9KD64, ISPG_CAMLR ;
DR   Q9A9W0, ISPG_CAUCR ;  B3PDM1, ISPG_CELJU ;  Q5L669, ISPG_CHLAB ;
DR   Q823I7, ISPG_CHLCV ;  Q254D2, ISPG_CHLFF ;  Q9PKY3, ISPG_CHLMU ;
DR   Q9Z8H0, ISPG_CHLPN ;  B0B9G5, ISPG_CHLT2 ;  Q3KMW4, ISPG_CHLTA ;
DR   B0BB44, ISPG_CHLTB ;  Q8KG23, ISPG_CHLTE ;  O84060, ISPG_CHLTR ;
DR   Q1QTK8, ISPG_CHRSD ;  Q7NS88, ISPG_CHRVO ;  A8AD71, ISPG_CITK8 ;
DR   A5CT01, ISPG_CLAM3 ;  B0RDZ5, ISPG_CLAMS ;  Q97I56, ISPG_CLOAB ;
DR   B8I6E1, ISPG_CLOCE ;  P58667, ISPG_CLOPE ;  Q895K3, ISPG_CLOTE ;
DR   Q47WC0, ISPG_COLP3 ;  Q6NGL3, ISPG_CORDI ;  Q8FP82, ISPG_COREF ;
DR   Q8NP12, ISPG_CORGL ;  Q4JV28, ISPG_CORJK ;  B1VGA4, ISPG_CORU7 ;
DR   B1WQF1, ISPG_CYAA5 ;  B8HSI6, ISPG_CYAP4 ;  B7KJJ4, ISPG_CYAP7 ;
DR   B7K5R5, ISPG_CYAP8 ;  Q47BR6, ISPG_DECAR ;  A5FS85, ISPG_DEHSB ;
DR   Q3ZZC9, ISPG_DEHSC ;  Q9RXC9, ISPG_DEIRA ;  C6BYK9, ISPG_DESAD ;
DR   Q6AP32, ISPG_DESPS ;  Q72CD9, ISPG_DESVH ;  A8LI72, ISPG_DINSH ;
DR   A7ZPV8, ISPG_ECO24 ;  B7UGW1, ISPG_ECO27 ;  B7MI00, ISPG_ECO45 ;
DR   B7LDA7, ISPG_ECO55 ;  P62622, ISPG_ECO57 ;  B5Z0Y4, ISPG_ECO5E ;
DR   B7NRG5, ISPG_ECO7I ;  B7MYF0, ISPG_ECO81 ;  B7M7L9, ISPG_ECO8A ;
DR   C4ZX90, ISPG_ECOBW ;  B1XAZ0, ISPG_ECODH ;  A8A321, ISPG_ECOHS ;
DR   A1AE53, ISPG_ECOK1 ;  Q0TEX0, ISPG_ECOL5 ;  P62621, ISPG_ECOL6 ;
DR   B1IWE6, ISPG_ECOLC ;  P62620, ISPG_ECOLI ;  B7N6A3, ISPG_ECOLU ;
DR   B6I587, ISPG_ECOSE ;  B1LNH0, ISPG_ECOSM ;  Q1R8L8, ISPG_ECOUT ;
DR   Q3YRZ7, ISPG_EHRCJ ;  Q5FHA6, ISPG_EHRRG ;  Q5HB57, ISPG_EHRRW ;
DR   A4WD93, ISPG_ENT38 ;  A7MGV7, ISPG_ENTS8 ;  Q6D276, ISPG_ERWCT ;
DR   B2VE89, ISPG_ERWT9 ;  B7LKC3, ISPG_ESCF3 ;  B1YLA2, ISPG_EXIS2 ;
DR   C4L3K5, ISPG_EXISA ;  Q0RDR2, ISPG_FRAAA ;  Q2J717, ISPG_FRASC ;
DR   A8L6E2, ISPG_FRASN ;  Q14IL6, ISPG_FRAT1 ;  B2SG03, ISPG_FRATM ;
DR   A0Q6U8, ISPG_FRATN ;  Q0BMA6, ISPG_FRATO ;  Q5NH64, ISPG_FRATT ;
DR   Q8RG40, ISPG_FUSNN ;  Q5KX35, ISPG_GEOKA ;  Q74D60, ISPG_GEOSL ;
DR   C5D4Q3, ISPG_GEOSW ;  A4IQZ4, ISPG_GEOTN ;  Q7NFA4, ISPG_GLOVI ;
DR   A9HJ48, ISPG_GLUDA ;  Q5FUR7, ISPG_GLUOX ;  Q0BUK0, ISPG_GRABC ;
DR   Q7VME2, ISPG_HAEDU ;  Q4QNH4, ISPG_HAEI8 ;  A5UAB9, ISPG_HAEIE ;
DR   A5UGH1, ISPG_HAEIG ;  P44667, ISPG_HAEIN ;  Q0I2E9, ISPG_HAES1 ;
DR   B0USG8, ISPG_HAES2 ;  Q2SDW4, ISPG_HAHCH ;  C4K4I8, ISPG_HAMD5 ;
DR   Q17XU2, ISPG_HELAH ;  Q7VI04, ISPG_HELHP ;  B6JLL3, ISPG_HELP2 ;
DR   B5Z6Z7, ISPG_HELPG ;  Q1CTP7, ISPG_HELPH ;  Q9ZLL0, ISPG_HELPJ ;
DR   B2UTK0, ISPG_HELPS ;  O25342, ISPG_HELPY ;  B4U9V3, ISPG_HYDS0 ;
DR   Q0C4J3, ISPG_HYPNA ;  Q5QYA9, ISPG_IDILO ;  Q28R10, ISPG_JANSC ;
DR   B5XNL5, ISPG_KLEP3 ;  A6TCD4, ISPG_KLEP7 ;  B2GKS3, ISPG_KOCRD ;
DR   C1DD43, ISPG_LARHH ;  Q1MSE5, ISPG_LAWIP ;  Q6AEX9, ISPG_LEIXX ;
DR   Q04UL2, ISPG_LEPBJ ;  Q04YW2, ISPG_LEPBL ;  Q72TR2, ISPG_LEPIC ;
DR   Q8F1H5, ISPG_LEPIN ;  C1L2Z7, ISPG_LISMC ;  Q71ZM9, ISPG_LISMF ;
DR   P58668, ISPG_LISMO ;  B1HSS4, ISPG_LYSSC ;  B9E6U1, ISPG_MACCJ ;
DR   A0LDN3, ISPG_MAGSM ;  Q65R84, ISPG_MANSM ;  A1TZQ0, ISPG_MARAV ;
DR   A6VV06, ISPG_MARMS ;  Q604Q5, ISPG_METCA ;  Q1H0U9, ISPG_METFK ;
DR   B0JJJ8, ISPG_MICAN ;  Q7TXN6, ISPG_MYCBO ;  A1KML3, ISPG_MYCBP ;
DR   C1AFY4, ISPG_MYCBT ;  Q7NBH3, ISPG_MYCGA ;  B8ZRU5, ISPG_MYCLB ;
DR   Q9CBU5, ISPG_MYCLE ;  Q73VS3, ISPG_MYCPA ;  Q8EUI6, ISPG_MYCPE ;
DR   A5U6M2, ISPG_MYCTA ;  O33350, ISPG_MYCTU ;  B2A390, ISPG_NATTJ ;
DR   B9LA27, ISPG_NAUPA ;  Q5F913, ISPG_NEIG1 ;  B4RMG4, ISPG_NEIG2 ;
DR   A9LZN8, ISPG_NEIM0 ;  Q9JU34, ISPG_NEIMA ;  Q9JZ40, ISPG_NEIMB ;
DR   A1KUD8, ISPG_NEIMF ;  Q0AE42, ISPG_NITEC ;  Q82XV0, ISPG_NITEU ;
DR   Q1QQI9, ISPG_NITHX ;  A6Q1U2, ISPG_NITSB ;  Q3SVD0, ISPG_NITWN ;
DR   Q5YS74, ISPG_NOCFA ;  B2J1G1, ISPG_NOSP7 ;  P58666, ISPG_NOSS1 ;
DR   A6WXY9, ISPG_OCHA4 ;  B6JA27, ISPG_OLICO ;  A6LGR5, ISPG_PARD8 ;
DR   A1B323, ISPG_PARDP ;  Q6MD85, ISPG_PARUW ;  P57987, ISPG_PASMU ;
DR   C6DBH4, ISPG_PECCP ;  Q4FNA0, ISPG_PELUB ;  C0QRI5, ISPG_PERMH ;
DR   Q7N706, ISPG_PHOLL ;  Q6LU49, ISPG_PHOPR ;  Q7MVT7, ISPG_PORGI ;
DR   Q6A7L2, ISPG_PROAC ;  Q7VBS7, ISPG_PROMA ;  B4EZT3, ISPG_PROMH ;
DR   Q7V7G9, ISPG_PROMM ;  Q7V215, ISPG_PROMP ;  P72241, ISPG_PROST ;
DR   Q48LZ4, ISPG_PSE14 ;  A6V0W0, ISPG_PSEA7 ;  B7UWI8, ISPG_PSEA8 ;
DR   Q02RV7, ISPG_PSEAB ;  Q9HXJ4, ISPG_PSEAE ;  Q1IEI1, ISPG_PSEE4 ;
DR   Q4K6U9, ISPG_PSEF5 ;  C3K1L4, ISPG_PSEFS ;  Q3ICZ5, ISPG_PSEHT ;
DR   A4XY32, ISPG_PSEMY ;  A5VYT5, ISPG_PSEP1 ;  Q3K7B6, ISPG_PSEPF ;
DR   B0KPI7, ISPG_PSEPG ;  Q88PJ7, ISPG_PSEPK ;  B1JDV8, ISPG_PSEPW ;
DR   Q886Z0, ISPG_PSESM ;  Q4ZX23, ISPG_PSEU2 ;  Q4FTW7, ISPG_PSYA2 ;
DR   Q1QD18, ISPG_PSYCK ;  A1SU39, ISPG_PSYIN ;  B2U9U9, ISPG_RALPJ ;
DR   P58669, ISPG_RALSO ;  A9WR14, ISPG_RENSM ;  B3PR71, ISPG_RHIE6 ;
DR   Q2K333, ISPG_RHIEC ;  Q1MAC5, ISPG_RHIL3 ;  Q98FG0, ISPG_RHILO ;
DR   B5ZUA0, ISPG_RHILW ;  Q92L19, ISPG_RHIME ;  C3MAL6, ISPG_RHISN ;
DR   Q7UWC8, ISPG_RHOBA ;  C1B2V4, ISPG_RHOOB ;  Q2J2S7, ISPG_RHOP2 ;
DR   Q07V91, ISPG_RHOP5 ;  Q6NCF3, ISPG_RHOPA ;  Q21C20, ISPG_RHOPB ;
DR   B3QBC6, ISPG_RHOPT ;  Q2RWE4, ISPG_RHORT ;  A1AW46, ISPG_RUTMC ;
DR   Q21KT3, ISPG_SACD2 ;  B5F198, ISPG_SALA4 ;  A8M723, ISPG_SALAI ;
DR   A9MHL5, ISPG_SALAR ;  Q57LI6, ISPG_SALCH ;  B5FR63, ISPG_SALDC ;
DR   B5R582, ISPG_SALEP ;  B5RCZ2, ISPG_SALG2 ;  B4TD93, ISPG_SALHS ;
DR   B4T0P9, ISPG_SALNS ;  Q5PNI2, ISPG_SALPA ;  A9N201, ISPG_SALPB ;
DR   B5BAY5, ISPG_SALPK ;  B4TR95, ISPG_SALSV ;  P58670, ISPG_SALTI ;
DR   A4X4L9, ISPG_SALTO ;  P58671, ISPG_SALTY ;  A8GHW5, ISPG_SERP5 ;
DR   A1S863, ISPG_SHEAM ;  B8E9S7, ISPG_SHEB2 ;  A3D6V9, ISPG_SHEB5 ;
DR   A6WQP7, ISPG_SHEB8 ;  A9KXK8, ISPG_SHEB9 ;  Q12PT4, ISPG_SHEDO ;
DR   Q085U6, ISPG_SHEFN ;  B0TLI4, ISPG_SHEHH ;  A3QCG2, ISPG_SHELP ;
DR   Q8EC32, ISPG_SHEON ;  A8H245, ISPG_SHEPA ;  A4Y8U0, ISPG_SHEPC ;
DR   B8CKR1, ISPG_SHEPW ;  A0KUJ5, ISPG_SHESA ;  A8FT70, ISPG_SHESH ;
DR   Q0HKV9, ISPG_SHESM ;  Q0HX57, ISPG_SHESR ;  A1RHQ3, ISPG_SHESW ;
DR   B1KKJ2, ISPG_SHEWM ;  B2TXU0, ISPG_SHIB3 ;  Q31XX5, ISPG_SHIBS ;
DR   Q32D47, ISPG_SHIDS ;  Q0T204, ISPG_SHIF8 ;  Q83K43, ISPG_SHIFL ;
DR   Q3YZ37, ISPG_SHISS ;  Q5LQ99, ISPG_SILPO ;  Q1GIC1, ISPG_SILST ;
DR   A6UE79, ISPG_SINMW ;  Q2NS40, ISPG_SODGM ;  Q029T9, ISPG_SOLUE ;
DR   B1VYP5, ISPG_STRGG ;  B4SRZ0, ISPG_STRM5 ;  B2FL74, ISPG_STRMK ;
DR   Q30TM4, ISPG_SULDN ;  A6QC65, ISPG_SULNB ;  B2V7Y2, ISPG_SULSY ;
DR   Q67PA7, ISPG_SYMTH ;  Q31QC4, ISPG_SYNE7 ;  Q2JS69, ISPG_SYNJA ;
DR   Q2JPZ9, ISPG_SYNJB ;  B1XHZ7, ISPG_SYNP2 ;  Q5N3W3, ISPG_SYNP6 ;
DR   Q7U712, ISPG_SYNPX ;  Q0I9J4, ISPG_SYNS3 ;  Q3AXP3, ISPG_SYNS9 ;
DR   Q3AK30, ISPG_SYNSC ;  P73672, ISPG_SYNY3 ;  B7IFY1, ISPG_THEAB ;
DR   Q8DK70, ISPG_THEEB ;  Q47RY0, ISPG_THEFY ;  A8F4Y8, ISPG_THELT ;
DR   Q9WZZ3, ISPG_THEMA ;  A5IIP2, ISPG_THEP1 ;  B1LC43, ISPG_THESQ ;
DR   Q72H18, ISPG_THET2 ;  Q5SLI8, ISPG_THET8 ;  Q84GJ3, ISPG_THETH ;
DR   Q8RA30, ISPG_THETN ;  B5YIQ4, ISPG_THEYD ;  Q73N90, ISPG_TREDE ;
DR   O83460, ISPG_TREPA ;  Q10W70, ISPG_TRIEI ;  Q83NE4, ISPG_TROW8 ;
DR   Q83N18, ISPG_TROWT ;  A5CX35, ISPG_VESOH ;  Q9KTX1, ISPG_VIBCH ;
DR   Q5E772, ISPG_VIBF1 ;  B5FAX2, ISPG_VIBFM ;  A7MU42, ISPG_VIBHB ;
DR   Q87S16, ISPG_VIBPA ;  B7VJT8, ISPG_VIBSL ;  Q8DEZ8, ISPG_VIBVU ;
DR   Q7MNF1, ISPG_VIBVY ;  Q8D1Y3, ISPG_WIGBR ;  Q73IP1, ISPG_WOLPM ;
DR   B3CNN4, ISPG_WOLPP ;  Q7M8Z2, ISPG_WOLSU ;  Q5GRK4, ISPG_WOLTR ;
DR   C0R5E5, ISPG_WOLWR ;  Q8PLJ8, ISPG_XANAC ;  Q3BUK3, ISPG_XANC5 ;
DR   Q4UTW8, ISPG_XANC8 ;  B0RTS9, ISPG_XANCB ;  Q8P9R7, ISPG_XANCP ;
DR   Q2P3M7, ISPG_XANOM ;  Q5H0N8, ISPG_XANOR ;  Q9PAE3, ISPG_XYLFA ;
DR   Q87A73, ISPG_XYLFT ;  A1JKS2, ISPG_YERE8 ;  A7FFY9, ISPG_YERP3 ;
DR   Q1C5I8, ISPG_YERPA ;  B2K9Q0, ISPG_YERPB ;  P58672, ISPG_YERPE ;
DR   A9R802, ISPG_YERPG ;  Q1CK91, ISPG_YERPN ;  A4TMT7, ISPG_YERPP ;
DR   Q667Z9, ISPG_YERPS ;  B1JS05, ISPG_YERPY ;  Q5NR50, ISPG_ZYMMO ;
//
ID   1.17.99.1
DE   4-methylphenol dehydrogenase (hydroxylating).
AN   4-cresol dehydrogenase (hydroxylating).
AN   p-cresol methylhydroxylase.
AN   p-cresol-(acceptor) oxidoreductase (hydroxylating).
CA   4-methylphenol + acceptor + H(2)O = 4-hydroxybenzaldehyde + reduced
CA   acceptor.
CF   FAD.
CC   -!- Phenazine methosulfate can act as acceptor.
CC   -!- A quinone methide is probably formed as intermediate.
CC   -!- The first hydroxylation forms 4-hydroxybenzyl alcohol; a second
CC       hydroxylation converts this into 4-hydroxybenzaldehyde.
DR   P09788, DH4C_PSEPU ;
//
ID   1.17.99.2
DE   Ethylbenzene hydroxylase.
AN   Ethylbenzene dehydrogenase.
CA   Ethylbenzene + H(2)O + acceptor = (S)-1-phenylethanol + reduced acceptor.
CF   Heme; Iron-sulfur; Molybdopterin.
CC   -!- Involved in the anaerobic catabolism of ethylbenzene by denitrifying
CC       bacteria.
CC   -!- Ethylbenzene is the preferred substrate; the enzyme from some strains
CC       oxidizes propylbenzene, 1-ethyl-4-fluorobenzene, 3-methylpent-2-ene
CC       and ethylidenecyclohexane.
CC   -!- Toluene is not oxidized.
CC   -!- p-benzoquinone or ferrocenium can act as electron acceptor.
//
ID   1.17.99.3
DE   3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA
DE   24-hydroxylase.
AN   3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-oate
AN   24-hydroxylase.
AN   3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase.
AN   THC-CoA oxidase.
AN   THCA-CoA oxidase.
AN   Trihydroxycoprostanoyl-CoA oxidase.
CA   (25R)-3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-oyl-CoA +
CA   H(2)O + acceptor = (24R,25R)-3-alpha,7-alpha,12-alpha,24-tetrahydroxy-5-
CA   beta-cholestan-26-oyl-CoA + reduced acceptor.
CC   -!- Requires ATP.
CC   -!- The reaction in mammals possibly involves dehydrogenation to give a
CC       24(25)-double bond followed by hydration.
CC   -!- However, in amphibians such as the Oriental fire-bellied toad
CC       (Bombina orientalis), it is probable that the product is formed via
CC       direct hydroxylation of the saturated side chain of (25R)-3-alpha,7-
CC       alpha,12-alpha-trihydroxy-5-beta-cholestan-26-oate and not via
CC       hydration of a 24(25) double bond.
CC   -!- In microsomes, the free acid is preferred to the coenzyme A ester,
CC       whereas in mitochondria, the coenzyme A ester is preferred to the
CC       free-acid form of the substrate.
DR   Q99424, ACOX2_HUMAN;  Q9QXD1, ACOX2_MOUSE;  O02767, ACOX2_RABIT;
DR   P97562, ACOX2_RAT  ;
//
ID   1.17.99.4
DE   Uracil/thymine dehydrogenase.
AN   Uracil dehydrogenase.
AN   Uracil oxidase.
AN   Uracil-thymine oxidase.
CA   (1) Uracil + H(2)O + acceptor = barbiturate + reduced acceptor.
CA   (2) Thymine + H(2)O + acceptor = 5-methylbarbiturate + reduced acceptor.
CC   -!- Forms part of the oxidative pyrimidine-degrading pathway in some
CC       microorganisms, along with EC 3.5.2.1 and EC 3.5.1.95.
CC   -!- Mammals, plants and other microorganisms utilize the reductive
CC       pathway, comprising EC 1.3.1.1 or EC 1.3.1.2, EC 3.5.2.2 and
CC       EC 3.5.1.6, with the ultimate degradation products being an L-amino
CC       acid, NH(3) and CO(2).
CC   -!- Formerly EC 1.1.99.19 and EC 1.2.99.1.
//
ID   1.17.99.5
DE   Bile-acid 7-alpha-dehydroxylase.
AN   7-alpha-dehydroxylase.
AN   Bile acid 7-dehydroxylase.
AN   Cholate 7-alpha-dehydroxylase.
CA   (1) Deoxycholate + FAD + H(2)O = cholate + FADH(2).
CA   (2) Lithocholate + FAD + H(2)O = chenodeoxycholate + FADH(2).
CC   -!- Under physiological conditions, the reactions occur in the reverse
CC       direction to that shown above.
CC   -!- Highly specific for bile-acid substrates and requires a free C-24
CC       carboxy group and an unhindered 7-alpha-hydroxy group on the B-ring
CC       of the steroid nucleus for activity, as found in cholate and
CC       chenodeoxycholate.
CC   -!- The reaction is stimulated by the presence of NAD(+) but is inhibited
CC       by excess NADH.
CC   -!- This unusual regulation by the NAD(+)/NADH ratio is most likely the
CC       result of the intermediates being linked at C-24 by an anhydride bond
CC       to the 5'-diphosphate of 3'-phospho-ADP.
CC   -!- Allo-deoxycholate is also formed as a side-product of the 7-alpha-
CC       dehydroxylation of cholate.
CC   -!- Formerly EC 1.17.1.6.
PR   PROSITE; PDOC00060;
DR   P07914, BAIA1_EUBSP;  P19337, BAIA2_EUBSP;
//
ID   1.18.1.1
DE   Rubredoxin--NAD(+) reductase.
AN   Dihydronicotinamide adenine dinucleotide-rubredoxin reductase.
AN   NADH-rubredoxin oxidoreductase.
AN   NADH-rubredoxin reductase.
AN   Reduced nicotinamide adenine dinucleotide-rubredoxin reductase.
AN   Rubredoxin reductase.
AN   Rubredoxin-NAD reductase.
AN   Rubredoxin-nicotinamide adenine dinucleotide reductase.
CA   2 reduced rubredoxin + NAD(+) + H(+) = 2 oxidized rubredoxin + NADH.
CF   FAD; Iron.
CC   -!- The enzyme from Clostridium acetobutylicum reduces rubredoxin,
CC       ferricyanide and dichlorophenolindophenol, but not ferredoxin or
CC       flavodoxin.
CC   -!- The reaction does not occur when NADPH is substituted for NADH.
CC   -!- Formerly EC 1.6.7.2.
DR   Q9AL95, NROR_CLOAB ;  P42454, RURE_ACIAD ;  Q0VTB0, RURE_ALCBS ;
DR   Q9HTK9, RURE_PSEAE ;  P17052, RURE_PSEOL ;  Q9L4M8, RURE_PSEPU ;
//
ID   1.18.1.2
DE   Ferredoxin--NADP(+) reductase.
AN   Adrenodoxin reductase.
AN   NADPH:adrenodoxin oxidoreductase.
CA   2 reduced ferredoxin + NADP(+) + H(+) = 2 oxidized ferredoxin + NADPH.
CF   FAD.
CC   -!- Also acts on adrenodoxin.
CC   -!- Formerly EC 1.6.7.1 and EC 1.6.99.4.
DR   P08165, ADRO_BOVIN ;  Q54KG7, ADRO_DICDI ;  Q9V3T9, ADRO_DROME ;
DR   P22570, ADRO_HUMAN ;  Q61578, ADRO_MOUSE ;  P56522, ADRO_RAT   ;
DR   P82861, ADRO_SALFO ;  O59710, ADRO_SCHPO ;  P48360, ADRO_YEAST ;
DR   A7Z171, FENR1_BACA2;  A0R951, FENR1_BACAH;  Q81ZB7, FENR1_BACAN;
DR   Q73EA6, FENR1_BACC1;  A7GKN4, FENR1_BACCN;  Q6HP49, FENR1_BACHK;
DR   Q65GY3, FENR1_BACLD;  A8FB45, FENR1_BACP2;  Q5WAF1, FENR1_BACSK;
DR   O31475, FENR1_BACSU;  A9VRK8, FENR1_BACWK;  B3QXE1, FENR1_CHLT3;
DR   Q0KCD1, FENR1_CUPNH;  Q473F6, FENR1_CUPPJ;  B3R4A7, FENR1_CUPTR;
DR   B1YKW2, FENR1_EXIS2;  A0LXL9, FENR1_GRAFK;  Q38YM3, FENR1_LACSS;
DR   Q92A47, FENR1_LISIN;  Q71Y53, FENR1_LISMF;  Q8Y5U4, FENR1_LISMO;
DR   A0AK73, FENR1_LISW6;  B1HZ05, FENR1_LYSSC;  Q8ETS1, FENR1_OCEIH;
DR   P41344, FENR1_ORYSJ;  P10933, FENR1_PEA  ;  Q1LPH7, FENR1_RALME;
DR   Q4JCM0, FENR1_SULAC;  O04977, FENR1_TOBAC;  A7Z8C1, FENR2_BACA2;
DR   A0RKB9, FENR2_BACAH;  Q81XS0, FENR2_BACAN;  Q72YF6, FENR2_BACC1;
DR   A7GUD5, FENR2_BACCN;  Q6HBX6, FENR2_BACHK;  Q65FE0, FENR2_BACLD;
DR   A8FH11, FENR2_BACP2;  Q5WDV1, FENR2_BACSK;  O05268, FENR2_BACSU;
DR   A9VMZ3, FENR2_BACWK;  B3QXR3, FENR2_CHLT3;  Q0K8J6, FENR2_CUPNH;
DR   Q46YY3, FENR2_CUPPJ;  B3R5L8, FENR2_CUPTR;  B1YEQ1, FENR2_EXIS2;
DR   A0LY71, FENR2_GRAFK;  Q38YJ1, FENR2_LACSS;  Q928P3, FENR2_LISIN;
DR   Q71X35, FENR2_LISMF;  Q8Y4P5, FENR2_LISMO;  A0AL74, FENR2_LISW6;
DR   B1I067, FENR2_LYSSC;  Q8ENX4, FENR2_OCEIH;  P41345, FENR2_ORYSJ;
DR   Q41014, FENR2_PEA  ;  Q1LKJ7, FENR2_RALME;  Q4J6Z4, FENR2_SULAC;
DR   O04397, FENR2_TOBAC;  B1HW35, FENR3_LYSSC;  O23877, FENR3_ORYSJ;
DR   A9NFF6, FENR_ACHLI ;  A1TRN6, FENR_ACIAC ;  A0LT79, FENR_ACIC1 ;
DR   A5FYH8, FENR_ACICJ ;  A1W6V2, FENR_ACISJ ;  Q5PAR7, FENR_ANAMM ;
DR   Q2GJY7, FENR_ANAPZ ;  P21890, FENR_ANASO ;  Q44549, FENR_ANAVT ;
DR   Q44532, FENR_AZOVI ;  Q816D9, FENR_BACCR ;  Q632D6, FENR_BACCZ ;
DR   Q9K7F3, FENR_BACHD ;  B2IHR5, FENR_BEII9 ;  Q89HV6, FENR_BRAJA ;
DR   A5EMW5, FENR_BRASB ;  A4YXZ8, FENR_BRASO ;  P57641, FENR_BUCAI ;
DR   Q9Z615, FENR_BUCAP ;  Q89A28, FENR_BUCBP ;  B2JN27, FENR_BURP8 ;
DR   B2T4Y1, FENR_BURPP ;  A4JS50, FENR_BURVG ;  Q13Y97, FENR_BURXL ;
DR   Q3AS18, FENR_CHLCH ;  B3EEF0, FENR_CHLL2 ;  B3QPZ8, FENR_CHLP8 ;
DR   B3EKW5, FENR_CHLPB ;  A1BHP4, FENR_CHLPD ;  P53991, FENR_CHLRE ;
DR   Q8KCB2, FENR_CHLTE ;  Q483W3, FENR_COLP3 ;  Q00598, FENR_CYAPA ;
DR   Q1IZM1, FENR_DEIGD ;  A9C3H6, FENR_DELAS ;  P28861, FENR_ECOLI ;
DR   Q3YS71, FENR_EHRCJ ;  Q2GGH5, FENR_EHRCR ;  Q5FH31, FENR_EHRRG ;
DR   Q5HBC7, FENR_EHRRW ;  Q82ZZ8, FENR_ENTFA ;  A5FJT9, FENR_FLAJ1 ;
DR   A6H064, FENR_FLAPJ ;  Q0RRX8, FENR_FRAAA ;  Q2JFM8, FENR_FRASC ;
DR   Q5KVP7, FENR_GEOKA ;  A4ISE6, FENR_GEOTN ;  A9H9C9, FENR_GLUDA ;
DR   Q5FT88, FENR_GLUOX ;  Q0BQJ9, FENR_GRABC ;  A8AA47, FENR_IGNH4 ;
DR   P84210, FENR_IMPCY ;  Q5FLU4, FENR_LACAC ;  Q03PJ4, FENR_LACBA ;
DR   Q03AW0, FENR_LACC3 ;  B3WCB2, FENR_LACCB ;  Q1G967, FENR_LACDA ;
DR   Q049B3, FENR_LACDB ;  B2GEF7, FENR_LACF3 ;  Q045M0, FENR_LACGA ;
DR   A8YTT2, FENR_LACH4 ;  Q74KS6, FENR_LACJO ;  Q9CF34, FENR_LACLA ;
DR   A2RJC6, FENR_LACLM ;  Q02XL9, FENR_LACLS ;  Q88UC0, FENR_LACPL ;
DR   A5VM22, FENR_LACRD ;  B2G9D0, FENR_LACRJ ;  Q1WUT6, FENR_LACS1 ;
DR   B1XWQ5, FENR_LEPCP ;  B1MX70, FENR_LEUCK ;  Q03ZE9, FENR_LEUMM ;
DR   Q2W0C9, FENR_MAGSA ;  P41343, FENR_MESCR ;  A2SFW9, FENR_METPP ;
DR   A4YER6, FENR_METS5 ;  Q7NBE9, FENR_MYCGA ;  Q8EWR4, FENR_MYCPE ;
DR   Q2GCZ2, FENR_NEOSM ;  Q1QNQ1, FENR_NITHX ;  Q3STP0, FENR_NITWN ;
DR   A1SKI3, FENR_NOCSJ ;  P58558, FENR_NOSS1 ;  Q04HB6, FENR_OENOB ;
DR   A5CF57, FENR_ORITB ;  B3CTT3, FENR_ORITI ;  A7HW48, FENR_PARL1 ;
DR   Q03H60, FENR_PEDPA ;  Q3B2Q8, FENR_PELLD ;  B4SFQ3, FENR_PELPB ;
DR   Q4FMZ1, FENR_PELUB ;  Q6L1Y6, FENR_PICTO ;  A1VQ12, FENR_POLNA ;
DR   Q12B36, FENR_POLSJ ;  A4SVT8, FENR_POLSQ ;  P84981, FENR_POPEU ;
DR   B4S9F8, FENR_PROA2 ;  A4SFT9, FENR_PROVI ;  B2U9D2, FENR_RALPJ ;
DR   Q8Y0A5, FENR_RALSO ;  Q98M06, FENR_RHILO ;  Q21VM4, FENR_RHOFD ;
DR   Q2ITC6, FENR_RHOP2 ;  Q07RK6, FENR_RHOP5 ;  Q6N2U4, FENR_RHOPA ;
DR   Q219B6, FENR_RHOPB ;  Q13AK7, FENR_RHOPS ;  B3QJ15, FENR_RHOPT ;
DR   Q2RNR2, FENR_RHORT ;  A8GNK2, FENR_RICAH ;  A8GW75, FENR_RICB8 ;
DR   Q1RHV1, FENR_RICBR ;  A8EYV4, FENR_RICCK ;  Q92HY3, FENR_RICCN ;
DR   Q4ULM2, FENR_RICFE ;  A8F1N2, FENR_RICM5 ;  Q9ZD33, FENR_RICPR ;
DR   B0BXN8, FENR_RICRO ;  A8GS72, FENR_RICRS ;  Q68WM0, FENR_RICTY ;
DR   A4F891, FENR_SACEN ;  A8M2W8, FENR_SALAI ;  A4X398, FENR_SALTO ;
DR   P28901, FENR_SHIFL ;  P00455, FENR_SPIOL ;  P00454, FENR_SPISP ;
DR   A7X5Z9, FENR_STAA1 ;  A6U499, FENR_STAA2 ;  Q2FEC4, FENR_STAA3 ;
DR   Q2FVP8, FENR_STAA8 ;  A5IVF3, FENR_STAA9 ;  Q2YZ12, FENR_STAAB ;
DR   Q5HDI3, FENR_STAAC ;  A6QJL4, FENR_STAAE ;  Q99RQ5, FENR_STAAM ;
DR   Q7A3W1, FENR_STAAN ;  Q6GE59, FENR_STAAR ;  Q6G6U7, FENR_STAAS ;
DR   A8Z563, FENR_STAAT ;  Q8NV36, FENR_STAAW ;  Q4L8N5, FENR_STAHJ ;
DR   Q49ZU9, FENR_STAS1 ;  Q3K0F9, FENR_STRA1 ;  Q8E4H8, FENR_STRA3 ;
DR   Q8DYW9, FENR_STRA5 ;  B4U394, FENR_STREM ;  A8AXQ6, FENR_STRGC ;
DR   Q8DUN5, FENR_STRMU ;  Q9A0B5, FENR_STRP1 ;  Q04JI5, FENR_STRP2 ;
DR   P0DB06, FENR_STRP3 ;  B5E6K6, FENR_STRP4 ;  Q5XCQ2, FENR_STRP6 ;
DR   Q8P1F2, FENR_STRP8 ;  Q1JCC9, FENR_STRPB ;  Q1JMB2, FENR_STRPC ;
DR   Q1JHF5, FENR_STRPD ;  Q1J776, FENR_STRPF ;  A2RF47, FENR_STRPG ;
DR   B1ICY3, FENR_STRPI ;  Q48U54, FENR_STRPM ;  Q97PP0, FENR_STRPN ;
DR   P0DB07, FENR_STRPQ ;  B2IR81, FENR_STRPS ;  B5XKX5, FENR_STRPZ ;
DR   Q8DP13, FENR_STRR6 ;  A4W460, FENR_STRS2 ;  A3CM39, FENR_STRSV ;
DR   A4VXW3, FENR_STRSY ;  Q5LYY3, FENR_STRT1 ;  Q5M3J6, FENR_STRT2 ;
DR   Q03JS2, FENR_STRTD ;  Q97WJ5, FENR_SULSO ;  Q96YN9, FENR_SULTO ;
DR   Q67QU3, FENR_SYMTH ;  P31973, FENR_SYNP2 ;  Q55318, FENR_SYNY3 ;
DR   Q93RE3, FENR_THEEB ;  Q72LG3, FENR_THET2 ;  Q5SL28, FENR_THET8 ;
DR   A1WQW2, FENR_VEREI ;  P41346, FENR_VICFA ;  Q73GH2, FENR_WOLPM ;
DR   B3CMJ8, FENR_WOLPP ;  Q5GRV1, FENR_WOLTR ;  Q9FKW6, FNRL1_ARATH;
DR   Q8W493, FNRL2_ARATH;  Q9M0V6, FNRR1_ARATH;  Q9S9P8, FNRR2_ARATH;
DR   O32886, FPRA_MYCLE ;  O05783, FPRA_MYCTU ;  P65529, FPRB_MYCBO ;
DR   O33064, FPRB_MYCLE ;  P65528, FPRB_MYCTU ;
//
ID   1.18.1.3
DE   Ferredoxin--NAD(+) reductase.
CA   Reduced ferredoxin + NAD(+) = oxidized ferredoxin + NADH.
CF   FAD.
CC   -!- Reaction (1) is written for a [2Fe-2S] ferredoxin, which is
CC       characteristic of some mono- and dioxygenase systems.
CC   -!- The alternative reaction (2) is written for a 2[4Fe-4S] ferredoxin,
CC       which transfers two electrons, and occurs in metabolism of anaerobic
CC       bacteria.
DR   Q07946, BEDA_PSEPU ;  P07771, BENC_ACIAD ;  P08087, BNZD_PSEPU ;
DR   P37337, BPHG_BURXL ;  Q51603, CBDC_BURCE ;  P24134, FENR_STRGR ;
DR   A7ZPY5, HCAD_ECO24 ;  B7LDD4, HCAD_ECO55 ;  Q8XA71, HCAD_ECO57 ;
DR   B5Z115, HCAD_ECO5E ;  B7NRJ1, HCAD_ECO7I ;  C4ZXB7, HCAD_ECOBW ;
DR   B1XB17, HCAD_ECODH ;  A8A348, HCAD_ECOHS ;  B1IVT5, HCAD_ECOLC ;
DR   P77650, HCAD_ECOLI ;  B7N6C9, HCAD_ECOLU ;  B6I5B5, HCAD_ECOSE ;
DR   B1LNJ8, HCAD_ECOSM ;  Q7N4V5, HCAD_PHOLL ;  Q0T1X7, HCAD_SHIF8 ;
DR   Q3YZ11, HCAD_SHISS ;  Q52126, NDOR_PSEPU ;  Q03304, TMOF_PSEME ;
DR   A5W4E9, TODA_PSEP1 ;  P0C621, TODA_PSEPU ;  P21394, XYLA_PSEPU ;
DR   P23101, XYLZ_PSEPU ;
//
ID   1.18.1.4
DE   Rubredoxin--NAD(P)(+) reductase.
AN   Dinucleotide phosphate reductase.
AN   NAD(P)-rubredoxin oxidoreductase.
AN   NAD(P)H-rubredoxin oxidoreductase.
AN   Rubredoxin-nicotinamide adenine.
AN   Rubredoxin-nicotinamide adenine dinucleotide (phosphate) reductase.
CA   Reduced rubredoxin + NAD(P)(+) = oxidized rubredoxin + NAD(P)H.
CF   FAD.
CC   -!- The enzyme reduces a number of electron carriers, including benzyl
CC       viologen, menadione and 2,6-dichloroindophenol, but rubredoxin is the
CC       most efficient.
CC   -!- Ferredoxin is not utilized.
//
ID   1.18.2.1
DE   Transferred entry: 1.18.6.1.
//
ID   1.18.3.1
DE   Transferred entry: 1.12.7.2.
//
ID   1.18.6.1
DE   Nitrogenase.
CA   8 reduced ferredoxin + 8 H(+) + N(2) + 16 ATP + 16 H(2)O = 8 oxidized
CA   ferredoxin + H(2) + 2 NH(3) + 16 ADP + 16 phosphate.
CF   Iron-sulfur; Vanadium or molybdenum.
CC   -!- Composed of two proteins that can be separated but are both required
CC       for nitrogenase activity.
CC   -!- Dinitrogen reductase is a [4Fe-4S] protein, which, with two molecules
CC       of ATP and ferredoxin, generates an electron.
CC   -!- The electron is transferred to the other protein, dinitrogenase
CC       (molybdoferredoxin).
CC   -!- Dinitrogenase is a molybdenum-iron protein that reduces dinitrogen in
CC       three succesive two-electron reductions from nitrogen to diimine to
CC       hydrazine to two molecules of ammonia; the molybdenum may be replaced
CC       by vanadium or iron.
CC   -!- The reduction is initiated by formation of hydrogen in stoichiometric
CC       amounts.
CC   -!- Acetylene is reduced to ethylene (but only very slowly to ethane),
CC       azide to nitrogen and ammonia, and cyanide to methane and ammonia.
CC   -!- In the absence of a suitable substrate, hydrogen is slowly formed.
CC   -!- Ferredoxin may be replaced by flavodoxin (see EC 1.19.6.1).
CC   -!- Formerly EC 1.18.2.1.
PR   PROSITE; PDOC00085;
PR   PROSITE; PDOC00580;
DR   P16266, ANFD_AZOVI ;  Q46082, ANFD_CLOHU ;  O68955, ANFD_HELGE ;
DR   Q07933, ANFD_RHOCA ;  O68946, ANFG_AZOMA ;  O68943, ANFG_AZOPA ;
DR   P16268, ANFG_AZOVI ;  Q46083, ANFG_CLOHU ;  Q46244, ANFG_CLOPA ;
DR   Q07934, ANFG_RHOCA ;  O68940, ANFG_RHORU ;  P16267, ANFK_AZOVI ;
DR   Q46084, ANFK_CLOHU ;  Q07935, ANFK_RHOCA ;  Q44045, NIFD_ALCFA ;
DR   P33177, NIFD_ANASL ;  P25313, NIFD_AZOBR ;  P07328, NIFD_AZOVI ;
DR   P06121, NIFD_BRAJA ;  P06120, NIFD_BRASP ;  P00467, NIFD_CLOPA ;
DR   O07642, NIFD_CYAA5 ;  Q55029, NIFD_CYAP8 ;  Q02452, NIFD_FRAAL ;
DR   P77874, NIFD_HERSE ;  P00466, NIFD_KLEPN ;  P55170, NIFD_METBA ;
DR   P51605, NIFD_METIV ;  P0CW50, NIFD_METMI ;  P0CW51, NIFD_METMP ;
DR   O27605, NIFD_METTH ;  P20620, NIFD_METTL ;  Q50788, NIFD_METTM ;
DR   P52337, NIFD_NOSCO ;  P00464, NIFD_NOSS1 ;  Q00239, NIFD_PLEBO ;
DR   P06769, NIFD_RHICP ;  P00465, NIFD_RHILT ;  P19066, NIFD_RHISN ;
DR   P08717, NIFD_RHOCA ;  P06662, NIFD_THIFE ;  P0A3S1, NIFH1_ANAVT;
DR   P26251, NIFH1_AZOC5;  P26248, NIFH1_AZOCH;  P00459, NIFH1_AZOVI;
DR   P00456, NIFH1_CLOPA;  Q47917, NIFH1_MASLA;  P54799, NIFH1_METBA;
DR   P51602, NIFH1_METIV;  O27602, NIFH1_METTH;  P25767, NIFH1_METTL;
DR   Q50785, NIFH1_METTM;  P00457, NIFH1_NOSS1;  Q9AKT8, NIFH1_PAEDU;
DR   P0CY95, NIFH1_RHOCA;  D5ANI3, NIFH1_RHOCB;  Q44484, NIFH2_ANAVT;
DR   P26252, NIFH2_AZOC5;  P06118, NIFH2_AZOCH;  P15335, NIFH2_AZOVI;
DR   P09552, NIFH2_CLOPA;  Q47921, NIFH2_MASLA;  P54800, NIFH2_METBA;
DR   P08624, NIFH2_METIV;  O26739, NIFH2_METTH;  P08625, NIFH2_METTL;
DR   O30577, NIFH2_NOSS1;  Q9AKT4, NIFH2_PAEDU;  Q07942, NIFH2_RHOCA;
DR   P16269, NIFH3_AZOVI;  P09553, NIFH3_CLOPA;  P22548, NIFH4_CLOPA;
DR   P09554, NIFH5_CLOPA;  P09555, NIFH6_CLOPA;  B7JA99, NIFH_ACIF2 ;
DR   B5ER76, NIFH_ACIF5 ;  Q44044, NIFH_ALCFA ;  A6TTY3, NIFH_ALKMQ ;
DR   P0A3S2, NIFH_ANAAZ ;  P33178, NIFH_ANASL ;  P17303, NIFH_AZOBR ;
DR   B6YRI6, NIFH_AZOPC ;  P06117, NIFH_BRAJA ;  P00463, NIFH_BRASP ;
DR   Q3AR70, NIFH_CHLCH ;  B3EH88, NIFH_CHLL2 ;  B3QQ12, NIFH_CHLP8 ;
DR   B3EL81, NIFH_CHLPB ;  A1BEH0, NIFH_CHLPD ;  Q8KC92, NIFH_CHLTE ;
DR   Q97ME5, NIFH_CLOAB ;  Q59270, NIFH_CLOCB ;  O07641, NIFH_CYAA5 ;
DR   B8HWE3, NIFH_CYAP4 ;  B7KG76, NIFH_CYAP7 ;  Q55028, NIFH_CYAP8 ;
DR   Q47G67, NIFH_DECAR ;  Q3Z7C7, NIFH_DEHE1 ;  B8FAC4, NIFH_DESAA ;
DR   C6BX34, NIFH_DESAD ;  C0QKK8, NIFH_DESAH ;  B1I0Y8, NIFH_DESAP ;
DR   P71156, NIFH_DESGI ;  C4XRK2, NIFH_DESMR ;  A4J8C2, NIFH_DESRM ;
DR   P26249, NIFH_ENTAG ;  Q6D2Y8, NIFH_ERWCT ;  P08925, NIFH_FRAAL ;
DR   Q2J4F8, NIFH_FRASC ;  Q47922, NIFH_FRASE ;  A8L2C4, NIFH_FRASN ;
DR   P46034, NIFH_FRASP ;  Q9ZIE4, NIFH_GLUDA ;  P77873, NIFH_HERSE ;
DR   B5XPH2, NIFH_KLEP3 ;  P00458, NIFH_KLEPN ;  A0L6X0, NIFH_MAGSM ;
DR   Q2FUB7, NIFH_METHJ ;  Q58289, NIFH_METJA ;  Q8PYY0, NIFH_METMA ;
DR   P0CW56, NIFH_METMI ;  A3CWW3, NIFH_METMJ ;  P0CW57, NIFH_METMP ;
DR   B8ITG7, NIFH_METNO ;  B0UAK2, NIFH_METS4 ;  P06119, NIFH_METVO ;
DR   P26250, NIFH_NOSCO ;  Q09158, NIFH_NOSMU ;  Q51296, NIFH_NOSS6 ;
DR   P52336, NIFH_NOSSN ;  Q3B2P6, NIFH_PELLD ;  B4SC59, NIFH_PELPB ;
DR   Q00240, NIFH_PLEBO ;  B4S9H5, NIFH_PROA2 ;  A4SFU6, NIFH_PROVI ;
DR   A4VJ70, NIFH_PSEU5 ;  P00462, NIFH_RHIET ;  P20623, NIFH_RHILE ;
DR   Q98AP7, NIFH_RHILO ;  P00461, NIFH_RHILT ;  P00460, NIFH_RHIME ;
DR   P19068, NIFH_RHISN ;  Q2J1I1, NIFH_RHOP2 ;  Q13C78, NIFH_RHOPS ;
DR   P22921, NIFH_RHORU ;  A3PLS9, NIFH_RHOS1 ;  Q3J0H1, NIFH_RHOS4 ;
DR   O31183, NIFH_RHOSH ;  A7NR80, NIFH_ROSCS ;  A5USK5, NIFH_ROSS1 ;
DR   A0LH11, NIFH_SYNFM ;  Q2JTL7, NIFH_SYNJA ;  Q2JP78, NIFH_SYNJB ;
DR   C5BTB0, NIFH_TERTT ;  P06661, NIFH_THIFE ;  C4LAS5, NIFH_TOLAT ;
DR   O34106, NIFH_TRIEI ;  P26254, NIFH_TRITH ;  Q0W443, NIFH_UNCMA ;
DR   Q7M8U8, NIFH_WOLSU ;  Q5NLG3, NIFH_ZYMMO ;  P25314, NIFK_AZOBR ;
DR   P07329, NIFK_AZOVI ;  P20621, NIFK_BRAJA ;  P06122, NIFK_BRASP ;
DR   P11347, NIFK_CLOPA ;  O07643, NIFK_CYAA5 ;  Q55030, NIFK_CYAP8 ;
DR   Q57118, NIFK_FRAAL ;  P77875, NIFK_HERSE ;  P09772, NIFK_KLEPN ;
DR   P51754, NIFK_METBA ;  P0CW52, NIFK_METMI ;  P0CW53, NIFK_METMP ;
DR   O27606, NIFK_METTH ;  P20622, NIFK_METTL ;  P95296, NIFK_METTM ;
DR   P00468, NIFK_NOSS1 ;  P19067, NIFK_RHISN ;  P15052, NIFK_THIFE ;
DR   P15332, VNFD_AZOCH ;  O68953, VNFD_AZOPA ;  O68954, VNFD_AZOSA ;
DR   P16855, VNFD_AZOVI ;  P15333, VNFG_AZOCH ;  O68951, VNFG_AZOSA ;
DR   P16857, VNFG_AZOVI ;  Q57302, VNFK_ANAVT ;  P15334, VNFK_AZOCH ;
DR   O68949, VNFK_AZOPA ;  O68952, VNFK_AZOSA ;  P16856, VNFK_AZOVI ;
//
ID   1.18.96.1
DE   Transferred entry: 1.15.1.2.
//
ID   1.18.99.1
DE   Transferred entry: 1.12.7.2.
//
ID   1.19.6.1
DE   Nitrogenase (flavodoxin).
CA   6 reduced flavodoxin + 6 H(+) + N(2) + n ATP = 6 oxidized flavodoxin +
CA   2 NH(3) + n ADP + n phosphate.
CF   Iron-sulfur; Molybdenum.
//
ID   1.20.1.1
DE   Phosphonate dehydrogenase.
AN   NAD-dependent phosphite dehydrogenas.
AN   NAD:phosphite oxidoreductase.
AN   Phosphite dehydrogenase.
CA   Phosphonate + NAD(+) + H(2)O = phosphate + NADH.
CC   -!- NADP(+) is a poor substitute for NAD(+) in the enzyme from
CC       Pseudomonas stutzeri WM88.
PR   PROSITE; PDOC00063;
DR   O69054, PTXD_PSEST ;
//
ID   1.20.4.1
DE   Arsenate reductase (glutaredoxin).
CA   Arsenate + glutaredoxin = arsenite + glutaredoxin disulfide + H(2)O.
CF   Molybdenum.
CC   -!- The glutaredoxins catalyze glutathione-disulfide oxidoreductions and
CC       have a redox-active disulfide/dithiol in the active site (-Cys-
CC       Pro-Tyr-Cys-) that forms a disulfide bond in the oxidized form.
CC   -!- Glutaredoxins have a binding site for glutathione, which is required
CC       to reduce them to the dithiol form.
CC   -!- Thioredoxins reduced by NADPH and thioredoxin reductase can act as
CC       alternative substrates.
CC   -!- The enzyme is part of a system for detoxifying arsenate.
CC   -!- Although the arsenite formed is more toxic than arsenate, it can be
CC       extruded from some bacteria by EC 3.6.3.16.
CC   -!- In other organisms, arsenite can be methylated by EC 2.1.1.137 in a
CC       pathway to non-toxic organoarsenical compounds.
CC   -!- Formerly EC 1.97.1.5.
DR   P08692, ARSC1_ECOLX;  P52147, ARSC2_ECOLX;  P0CF87, ARSCL_ECOLI;
DR   O50595, ARSC_ACIMA ;  P0AB96, ARSC_ECOLI ;  P44589, ARSC_HAEIN ;
DR   P95354, ARSC_NEIGO ;  P63621, ARSC_NEIMA ;  P63622, ARSC_NEIMB ;
DR   P0AB97, ARSC_SHIFL ;  P74984, ARSC_YEREN ;
//
ID   1.20.4.2
DE   Methylarsonate reductase.
AN   MMA(V) reductase.
CA   Methylarsonate + 2 glutathione = methylarsonite + glutathione disulfide +
CA   H(2)O.
CC   -!- The product, Me-As(OH)(2) (methylarsonous acid), is biologically
CC       methylated by EC 2.1.1.137 to form cacodylic acid (dimethylarsinic
CC       acid).
CC   -!- Formerly EC 1.97.1.7.
//
ID   1.20.4.3
DE   Mycoredoxin.
CA   Arseno-mycothiol + mycoredoxin = arsenite + mycothiol-
CA   mycoredoxin disulfide.
CC   -!- Reduction of arsenate is part of a defense mechanism of the cell
CC       against toxic arsenate.
CC   -!- The substrate arseno-mycothiol is formed by EC 2.8.4.2.
CC   -!- A second mycothiol recycles mycoredoxin and forms mycothione.
//
ID   1.20.98.1
DE   Arsenate reductase (azurin).
AN   Arsenite oxidase.
CA   Arsenite + H(2)O + 2 oxidized azurin = arsenate + 2 reduced azurin +
CA   2 H(+).
CF   Iron-sulfur; Molybdenum; Molybdopterin.
CC   -!- The enzyme also uses a c-type cytochrome or O(2) as acceptors.
DR   Q7SIF4, AOXB_ALCFA ;  Q8GGJ6, ARSL_HERAR ;  Q7SIF3, ARSS_ALCFA ;
DR   Q8GGJ7, ARSS_HERAR ;
//
ID   1.20.99.1
DE   Arsenate reductase (donor).
CA   Arsenite + acceptor = arsenate + reduced acceptor.
CC   -!- Benzyl viologen can act as an acceptor.
CC   -!- Unlike EC 1.20.4.1 reduced glutaredoxin cannot serve as a reductant.
CC   -!- Formerly EC 1.97.1.6.
//
ID   1.21.3.1
DE   Isopenicillin-N synthase.
CA   N-((5S)-5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine + O(2) =
CA   isopenicillin N + 2 H(2)O.
CC   -!- Forms part of the penicillin biosynthesis pathway.
PR   PROSITE; PDOC51471;
DR   P05189, IPNS_CEPAC ;  P05326, IPNS_EMENI ;  P16020, IPNS_FLASS ;
DR   Q48739, IPNS_LYSLA ;  P27744, IPNS_NOCLA ;  P08703, IPNS_PENCH ;
DR   P10621, IPNS_STRCL ;  Q53932, IPNS_STRCT ;  Q54243, IPNS_STRGR ;
DR   P18286, IPNS_STRJU ;  P12438, IPNS_STRMI ;
//
ID   1.21.3.2
DE   Columbamine oxidase.
AN   Berberine synthase.
CA   2 columbamine + O(2) = 2 berberine + 2 H(2)O.
CF   Iron.
CC   -!- Oxidation of the O-methoxyphenol structure forms the methylenedioxy
CC       group of berberine.
CC   -!- Formerly EC 1.1.3.26.
//
ID   1.21.3.3
DE   Reticuline oxidase.
AN   Berberine bridge enzyme.
AN   Berberine-bridge-forming enzyme.
AN   Tetrahydroprotoberberine synthase.
CA   (S)-reticuline + O(2) = (S)-scoulerine + H(2)O(2).
CF   FAD.
CC   -!- The product of the reaction, (S)-scoulerine, is a precursor of
CC       protopine, protoberberine and benzophenanthridine alkaloid
CC       biosynthesis in plants.
CC   -!- Acts on (S)-reticuline and related compounds, converting the N-methyl
CC       group into the methylene bridge ('berberine bridge') of (S)-
CC       tetrahydroprotoberberines.
CC   -!- Formerly EC 1.5.3.9.
PR   PROSITE; PDOC00674;
DR   P30986, RETO_ESCCA ;  P93479, RETO_PAPSO ;
//
ID   1.21.3.4
DE   Sulochrin oxidase ((+)-bisdechlorogeodin-forming).
AN   Sulochrin oxidase.
CA   2 sulochrin + O(2) = 2 (+)-bisdechlorogeodin + 2 H(2)O.
CC   -!- Also acts on several diphenols and phenylenediamines, but has low
CC       affinity for these substrates.
CC   -!- Involved in the biosynthesis of mold metabolites related to the
CC       antibiotic griseofulvin.
CC   -!- Formerly EC 1.10.3.7.
//
ID   1.21.3.5
DE   Sulochrin oxidase ((-)-bisdechlorogeodin-forming).
AN   Sulochrin oxidase.
CA   2 sulochrin + O(2) = 2 (-)-bisdechlorogeodin + 2 H(2)O.
CC   -!- Also acts on several diphenols and phenylenediamines, but has low
CC       affinity for these substrates.
CC   -!- Involved in the biosynthesis of mold metabolites related to the
CC       antibiotic griseofulvin.
CC   -!- Formerly EC 1.10.3.8.
//
ID   1.21.3.6
DE   Aureusidin synthase.
CA   (1) 2',4,4',6'-tetrahydroxychalcone + O(2) = aureusidin + H(2)O.
CA   (2) 2 2',3,4,4',6'-pentahydroxychalcone + O(2) = 2 aureusidin + 2 H(2)O.
CF   Copper.
CC   -!- Plays a key role in the yellow coloration of flowers such as
CC       snapdragon.
CC   -!- The enzyme is a homolog of plant polyphenol oxidase and catalyzes two
CC       separate chemical transformations, i.e. 3-hydroxylation and oxidative
CC       cyclization (2',alpha-dehydrogenation).
CC   -!- H(2)O(2) activates reaction (1) but inhibits reaction (2).
//
ID   1.21.4.1
DE   D-proline reductase (dithiol).
CA   5-aminopentanoate + lipoate = D-proline + dihydrolipoate.
CF   Pyruvate.
CC   -!- The reaction is observed only in the direction of D-proline
CC       reduction.
CC   -!- Other dithiols can function as reducing agents; the enzyme contains a
CC       pyruvoyl group and a selenocysteine residue, both essential for
CC       activity.
CC   -!- Formerly EC 1.4.1.6 and EC 1.4.4.1.
DR   Q9Z4P6, PRDA_CLOSD ;  Q9Z4Q7, PRDB_CLOSD ;
//
ID   1.21.4.2
DE   Glycine reductase.
CA   Acetyl phosphate + NH(3) + thioredoxin disulfide + H(2)O = glycine +
CA   phosphate + thioredoxin.
CC   -!- The reaction is observed only in the direction of glycine reduction.
CC   -!- The enzyme from Eubacterium acidaminophilum consists of subunits A,
CC       B and C.
CC   -!- Subunit B contains selenocysteine and a pyruvoyl group, and is
CC       responsible for glycine binding and ammonia release.
CC   -!- Subunit A, which also contains selenocysteine, is reduced by
CC       thioredoxin, and is needed to convert the carboxymethyl group into a
CC       ketene equivalent, in turn used by subunit C to produce acetyl
CC       phosphate.
CC   -!- Only subunit B distinguishes this enzyme from EC 1.21.4.3 and
CC       EC 1.21.4.4.
DR   P50972, GRDA1_EUBAC;  Q6LH20, GRDA1_PHOPR;  O32518, GRDA2_EUBAC;
DR   Q6LH19, GRDA2_PHOPR;  A6TU46, GRDA_ALKMQ ;  Q3A9J5, GRDA_CARHZ ;
DR   A7FTE0, GRDA_CLOB1 ;  A7GCV1, GRDA_CLOBL ;  P52216, GRDA_CLOLI ;
DR   P26970, GRDA_CLOPU ;  P26971, GRDA_CLOSD ;  Q67KE6, GRDA_SYMTH ;
DR   Q73PQ2, GRDA_TREDE ;  Q3A9J4, GRDB_CARHZ ;  P52217, GRDB_CLOLI ;
DR   P55793, GRDB_CLOPU ;  Q9R4G8, GRDB_EUBAC ;  Q67KE7, GRDB_SYMTH ;
DR   P54935, GRDC_EUBAC ;  Q47878, GRDD_EUBAC ;  Q9EV94, GRDE_CLOSD ;
DR   Q9R4G7, GRDE_EUBAC ;
//
ID   1.21.4.3
DE   Sarcosine reductase.
CA   Acetyl phosphate + methylamine + thioredoxin disulfide + H(2)O =
CA   N-methylglycine + phosphate + thioredoxin.
CC   -!- The reaction is observed only in the direction of sarcosine
CC       reduction.
CC   -!- The enzyme from Eubacterium acidaminophilum consists of subunits A,
CC       B and C.
CC   -!- Subunit B contains selenocysteine and a pyruvoyl group, and is
CC       responsible for sarcosine binding and methylamine release.
CC   -!- Subunit A, which also contains selenocysteine, is reduced by
CC       thioredoxin, and is needed to convert the carboxymethyl group into a
CC       ketene equivalent, in turn used by subunit C to produce acetyl
CC       phosphate.
CC   -!- Only subunit B distinguishes this enzyme from EC 1.21.4.2 and
CC       EC 1.21.4.4.
DR   P50972, GRDA1_EUBAC;  Q6LH20, GRDA1_PHOPR;  O32518, GRDA2_EUBAC;
DR   Q6LH19, GRDA2_PHOPR;  A6TU46, GRDA_ALKMQ ;  Q3A9J5, GRDA_CARHZ ;
DR   A7FTE0, GRDA_CLOB1 ;  A7GCV1, GRDA_CLOBL ;  P52216, GRDA_CLOLI ;
DR   P26970, GRDA_CLOPU ;  P26971, GRDA_CLOSD ;  Q67KE6, GRDA_SYMTH ;
DR   Q73PQ2, GRDA_TREDE ;  P54935, GRDC_EUBAC ;  Q47878, GRDD_EUBAC ;
DR   O86186, GRDF_EUBAC ;  O86185, GRDG_EUBAC ;
//
ID   1.21.4.4
DE   Betaine reductase.
CA   Acetyl phosphate + trimethylamine + thioredoxin disulfide + H(2)O =
CA   betaine + phosphate + thioredoxin.
CC   -!- The reaction is observed only in the direction of betaine reduction.
CC   -!- The enzyme from Eubacterium acidaminophilum consists of subunits A,
CC       B and C.
CC   -!- Subunit B contains selenocysteine and a pyruvoyl group, and is
CC       responsible for glycine binding and ammonia release.
CC   -!- Subunit A, which also contains selenocysteine, is reduced by
CC       thioredoxin, and is needed to convert the carboxymethyl group into a
CC       ketene equivalent, in turn used by subunit C to produce acetyl
CC       phosphate.
CC   -!- Only subunit B distinguishes this enzyme from EC 1.21.4.2 and
CC       EC 1.21.4.3.
DR   P50972, GRDA1_EUBAC;  Q6LH20, GRDA1_PHOPR;  O32518, GRDA2_EUBAC;
DR   Q6LH19, GRDA2_PHOPR;  A6TU46, GRDA_ALKMQ ;  Q3A9J5, GRDA_CARHZ ;
DR   A7FTE0, GRDA_CLOB1 ;  A7GCV1, GRDA_CLOBL ;  P52216, GRDA_CLOLI ;
DR   P26970, GRDA_CLOPU ;  P26971, GRDA_CLOSD ;  Q67KE6, GRDA_SYMTH ;
DR   Q73PQ2, GRDA_TREDE ;  P54935, GRDC_EUBAC ;  Q47878, GRDD_EUBAC ;
DR   O69407, GRDH_EUBAC ;  O69406, GRDI_EUBAC ;
//
ID   1.21.99.1
DE   Beta-cyclopiazonate dehydrogenase.
AN   Beta-cyclopiazonate oxidocyclase.
AN   Beta-cyclopiazonic oxidocyclase.
CA   Beta-cyclopiazonate + acceptor = alpha-cyclopiazonate + reduced acceptor.
CF   FAD.
CC   -!- Cytochrome c and various dyes can act as acceptor.
CC   -!- Cyclopiazonate is a microbial toxin.
CC   -!- Formerly EC 1.3.99.9.
//
ID   1.22.1.1
DE   Iodotyrosine deiodinase.
AN   Iodotyrosine dehalogenase 1.
CA   (1) L-tyrosine + NADP(+) + I(-) = 3-iodo-L-tyrosine + NADPH.
CA   (2) 3-iodo-L-tyrosine + NADP(+) + I(-) = 3,5-diiodo-L-tyrosine + NADPH.
CF   FMN.
CC   -!- The enzyme activity has only been demonstrated in the direction of
CC       3-deiodination.
CC   -!- Present in a transmembrane flavoprotein.
DR   Q6PHW0, IYD1_HUMAN ;  Q9DCX8, IYD1_MOUSE ;  Q6TA49, IYD1_PIG   ;
DR   Q5REW1, IYD1_PONAB ;  Q5BK17, IYD1_RAT   ;
//
ID   1.97.1.1
DE   Chlorate reductase.
CA   AH(2) + chlorate = A + H(2)O + chlorite.
CC   -!- Flavins or benzylviologen can act as acceptor.
DR   P60068, CLRA_IDEDE ;  P83448, CLRA_PSECO ;  P83449, CLRB_PSECO ;
DR   P83450, CLRG_PSECO ;
//
ID   1.97.1.2
DE   Pyrogallol hydroxytransferase.
AN   Pyrogallol hydroxyltransferase.
AN   Transhydroxylase.
CA   1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,3,5-
CA   trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene.
CF   Molybdenum.
CC   -!- 1,2,3,5-tetrahydroxybenzene acts as a cosubstrate for the conversion
CC       of pyrogallol into phloroglucinol, and for a number of similar
CC       isomerizations.
CC   -!- The enzyme is provisionally listed here, but might be considered as
CC       the basis for a new class in the transferases, analogous to the
CC       aminotransferases.
DR   P80563, PGTL_PELAC ;  P80564, PGTS_PELAC ;
//
ID   1.97.1.3
DE   Sulfur reductase.
CA   Reduction of elemental sulfur or polysulfide to hydrogen sulfide.
CC   -!- Sulfur can be reduced with hydrogen as donor in the presence of
CC       hydrogenase, or by photochemical reduction in the presence of
CC       phenosafranin.
//
ID   1.97.1.4
DE   [Formate-C-acetyltransferase]-activating enzyme.
AN   [Pyruvate formate-lyase]-activating enzyme.
AN   Formate acetyltransferase activating enzyme.
AN   Formate acetyltransferase-glycine dihydroflavodoxin:S-adenosyl-L-
AN   methionine oxidoreductase (S-adenosyl-L-methionine cleaving).
AN   PFL activase.
AN   PFL-glycine:S-adenosyl-L-methionine H transferase (flavodoxin-oxidizing,
AN   S-adenosyl-L-methionine-cleaving).
CA   S-adenosyl-L-methionine + dihydroflavodoxin + [formate
CA   C-acetyltransferase]-glycine = 5'-deoxyadenosine + L-methionine +
CA   flavodoxin semiquinone + [formate C-acetyltransferase]-glycin-2-yl
CA   radical.
CF   Iron-sulfur.
CC   -!- A single glycine residue in EC 2.3.1.54 is oxidized to the
CC       corresponding radical by transfer of H from its CH(2) to AdoMet with
CC       concomitant cleavage of the latter.
CC   -!- The first stage is reduction of the AdoMet to give methionine and the
CC       5'-deoxyadenosin-5-yl radical, which then abstracts a hydrogen
CC       radical from the glycine residue.
PR   PROSITE; PDOC00834;
DR   Q46267, PFLA_CLOPA ;  P0A9N6, PFLA_ECO57 ;  P0A9N5, PFLA_ECOL6 ;
DR   P0A9N4, PFLA_ECOLI ;  P43751, PFLA_HAEIN ;  P0A443, PFLA_LISIN ;
DR   Q71ZR3, PFLA_LISMF ;  P0A442, PFLA_LISMO ;  P0A9N7, PFLA_SHIFL ;
DR   Q2FK43, PFLA_STAA3 ;  Q2G1D7, PFLA_STAA8 ;  Q2YV52, PFLA_STAAB ;
DR   Q5HJF3, PFLA_STAAC ;  Q99WZ6, PFLA_STAAM ;  Q7A7X5, PFLA_STAAN ;
DR   Q6GK89, PFLA_STAAR ;  Q6GCP9, PFLA_STAAS ;  Q7A1W8, PFLA_STAAW ;
DR   Q5HKI0, PFLA_STAEQ ;  Q8CTX5, PFLA_STAES ;  O68575, PFLA_STRMU ;
DR   P32675, PFLC_ECOLI ;  P75794, PFLE_ECOLI ;
//
ID   1.97.1.5
DE   Transferred entry: 1.20.4.1.
//
ID   1.97.1.6
DE   Transferred entry: 1.20.99.1.
//
ID   1.97.1.7
DE   Transferred entry: 1.20.4.2.
//
ID   1.97.1.8
DE   Tetrachloroethene reductive dehalogenase.
AN   Tetrachloroethene reductase.
CA   Trichloroethene + chloride + acceptor = tetrachloroethene +
CA   reduced acceptor.
CF   Iron-sulfur.
CC   -!- This enzyme allows the common pollutant tetrachloroethene to support
CC       bacterial growth and is responsible for disposal of a number of
CC       chlorinated hydrocarbons by this organism.
CC   -!- The reaction occurs in the reverse direction.
CC   -!- The enzyme also reduces trichloroethene to dichloroethene.
CC   -!- Although the physiological reductant is unknown, the supply of
CC       reductant in some organisms is via reduced menaquinone, itself formed
CC       from molecular hydrogen, via EC 1.12.99.3.
CC   -!- Methyl viologen can act as electron donor.
//
ID   1.97.1.9
DE   Selenate reductase.
CA   Selenite + H(2)O + acceptor = selenate + reduced acceptor.
CF   Heme; Iron-sulfur; Molybdenum.
CC   -!- The periplasmic enzyme from Thauera selenatis is a complex comprising
CC       three heterologous subunits (alpha, beta and gamma).
CC   -!- Nitrate, nitrite, chlorate and sulfate are not substrates.
CC   -!- A number of compounds, including acetate, lactate, pyruvate,
CC       and certain sugars, amino acids, fatty acids, di- and tricarboxylic
CC       acids, and benzoate can serve as electron donors.
DR   Q9S1H0, SERA_THASE ;  Q9S1G9, SERB_THASE ;  Q9S1G7, SERC_THASE ;
//
ID   1.97.1.10
DE   Thyroxine 5'-deiodinase.
AN   Diiodothyronine 5'-deiodinase.
AN   Iodothyronine 5'-deiodinase.
AN   Iodothyronine outer ring monodeiodinase.
AN   L-thyroxine iodohydrolase (reducing).
AN   Thyroxine 5-deiodinase.
AN   Type I iodothyronine deiodinase.
AN   Type II iodothyronine deiodinase.
CA   3,5,3'-triiodo-L-thyronine + iodide + A + H(+) = L-thyroxine + AH(2).
CC   -!- The enzyme activity has only been demonstrated in the direction of
CC       5'-deiodination, which renders the thyroid hormone more active.
CC   -!- The enzyme consists of type I and type II enzymes, both containing
CC       selenocysteine, but with different kinetics.
CC   -!- For the type I enzyme the first reaction is a reductive deiodination
CC       converting the -Se-H group of the enzyme into an -Se-I group; the
CC       reductant then reconverts this into -Se-H, releasing iodide.
CC   -!- Formerly EC 3.8.1.4.
PR   PROSITE; PDOC00172;
PR   PROSITE; PDOC00925;
DR   P49894, IOD1_CANFA ;  O42411, IOD1_CHICK ;  Q6V915, IOD1_FELCA ;
DR   Q804E1, IOD1_FUNHE ;  P49895, IOD1_HUMAN ;  Q61153, IOD1_MOUSE ;
DR   O42449, IOD1_ORENI ;  Q6QN13, IOD1_PIG   ;  A4GT88, IOD1_RABIT ;
DR   P24389, IOD1_RAT   ;  Q95N00, IOD1_SUNMU ;  Q2QEI3, IOD1_XENLA ;
DR   Q5I3B2, IOD2_BOVIN ;  Q9IAX2, IOD2_CHICK ;  P79747, IOD2_FUNHE ;
DR   Q92813, IOD2_HUMAN ;  Q9Z1Y9, IOD2_MOUSE ;  Q8UVX8, IOD2_NEOFS ;
DR   Q6QN12, IOD2_PIG   ;  P49896, IOD2_RANCA ;  P70551, IOD2_RAT   ;
//
ID   1.97.1.11
DE   Thyroxine 5-deiodinase.
AN   Diiodothyronine 5'-deiodinase.
AN   Iodothyronine 5-deiodinase.
AN   Iodothyronine inner ring monodeiodinase.
AN   Type III iodothyronine deiodinase.
CA   3,3',5'-triiodo-L-thyronine + iodide + A + H(+) = L-thyroxine + AH(2).
CC   -!- The enzyme activity has only been demonstrated in the direction of
CC       5-deiodination.
CC   -!- This removal of the 5-iodine, i.e. from the inner ring, largely
CC       inactivates the hormone thyroxine.
PR   PROSITE; PDOC00172;
PR   PROSITE; PDOC00925;
DR   Q5I3B1, IOD3_BOVIN ;  O42412, IOD3_CHICK ;  P55073, IOD3_HUMAN ;
DR   Q91ZI8, IOD3_MOUSE ;  Q6QN11, IOD3_PIG   ;  P49898, IOD3_RANCA ;
DR   P49897, IOD3_RAT   ;  Q6DN07, IOD3_SHEEP ;  A7YD35, IOD3_SPAAU ;
DR   P49899, IOD3_XENLA ;
//
ID   1.98.1.1
DE   Transferred entry: 1.12.7.2.
//
ID   1.99.1.1
DE   Transferred entry: 1.14.14.1.
//
ID   1.99.1.2
DE   Transferred entry: 1.14.16.1.
//
ID   1.99.1.3
DE   Deleted entry.
//
ID   1.99.1.4
DE   Deleted entry.
//
ID   1.99.1.5
DE   Transferred entry: 1.14.13.9.
//
ID   1.99.1.6
DE   Deleted entry.
//
ID   1.99.1.7
DE   Transferred entry: 1.14.15.4.
//
ID   1.99.1.8
DE   Deleted entry.
//
ID   1.99.1.9
DE   Transferred entry: 1.14.99.9.
//
ID   1.99.1.10
DE   Deleted entry.
//
ID   1.99.1.11
DE   Transferred entry: 1.14.99.10.
//
ID   1.99.1.12
DE   Deleted entry.
//
ID   1.99.1.13
DE   Transferred entry: 1.14.99.7 and 5.4.99.7.
//
ID   1.99.1.14
DE   Transferred entry: 1.13.11.27.
//
ID   1.99.2.1
DE   Transferred entry: 1.13.11.12.
//
ID   1.99.2.2
DE   Transferred entry: 1.13.11.1.
//
ID   1.99.2.3
DE   Transferred entry: 1.13.11.3.
//
ID   1.99.2.4
DE   Transferred entry: 1.13.11.4.
//
ID   1.99.2.5
DE   Transferred entry: 1.13.11.5.
//
ID   1.99.2.6
DE   Transferred entry: 1.13.99.1.
//
ID   2.1.1.1
DE   Nicotinamide N-methyltransferase.
CA   S-adenosyl-L-methionine + nicotinamide = S-adenosyl-L-homocysteine +
CA   1-methylnicotinamide.
PR   PROSITE; PDOC00844;
DR   P40261, NNMT_HUMAN ;  O55239, NNMT_MOUSE ;  Q06AV1, NNMT_PIG   ;
DR   Q74ZB5, NNT1_ASHGO ;  Q4WYS7, NNT1_ASPFU ;  Q5A013, NNT1_CANAL ;
DR   Q6FJ22, NNT1_CANGA ;  P0CP45, NNT1_CRYNB ;  P0CP44, NNT1_CRYNJ ;
DR   Q6BKI8, NNT1_DEBHA ;  Q5BAD0, NNT1_EMENI ;  Q4I2X5, NNT1_GIBZE ;
DR   Q6CUI0, NNT1_KLULA ;  Q7S634, NNT1_NEUCR ;  Q9UT28, NNT1_SCHPO ;
DR   Q6CHE9, NNT1_YARLI ;  Q05874, NNT1_YEAST ;
//
ID   2.1.1.2
DE   Guanidinoacetate N-methyltransferase.
CA   S-adenosyl-L-methionine + guanidinoacetate = S-adenosyl-L-homocysteine +
CA   creatine.
DR   Q7ZXG7, GAMTA_XENLA;  Q5HZ68, GAMTB_XENLA;  Q2TBQ3, GAMT_BOVIN ;
DR   Q71N41, GAMT_DANRE ;  Q14353, GAMT_HUMAN ;  O35969, GAMT_MOUSE ;
DR   P10868, GAMT_RAT   ;  Q6PBF6, GAMT_XENTR ;
//
ID   2.1.1.3
DE   Thetin--homocysteine S-methyltransferase.
CA   Dimethylsulfonioacetate + L-homocysteine = S-methylthioglycolate +
CA   L-methionine.
//
ID   2.1.1.4
DE   Acetylserotonin O-methyltransferase.
AN   Hydroxyindole O-methyltransferase.
CA   S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine +
CA   N-acetyl-5-methoxytryptamine.
CC   -!- Some other hydroxyindoles also act as acceptor, more slowly.
DR   P10950, HIOM_BOVIN ;  Q92056, HIOM_CHICK ;  P46597, HIOM_HUMAN ;
DR   Q8HZJ0, HIOM_MACMU ;
//
ID   2.1.1.5
DE   Betaine--homocysteine S-methyltransferase.
CA   Trimethylammonioacetate + L-homocysteine = dimethylglycine +
CA   L-methionine.
CF   Zinc.
DR   Q5I597, BHMT1_BOVIN;  Q32LQ4, BHMT1_DANRE;  Q93088, BHMT1_HUMAN;
DR   O35490, BHMT1_MOUSE;  Q95332, BHMT1_PIG  ;  Q5RFG2, BHMT1_PONAB;
DR   O09171, BHMT1_RAT  ;  Q5XGM3, BHMT1_XENLA;  Q5M8Z0, BHMT1_XENTR;
DR   Q9H2M3, BHMT2_HUMAN;  Q91WS4, BHMT2_MOUSE;  Q5RF32, BHMT2_PONAB;
DR   Q68FT5, BHMT2_RAT  ;
//
ID   2.1.1.6
DE   Catechol O-methyltransferase.
CA   S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine +
CA   a guaiacol.
CC   -!- The mammalian enzymes act more rapidly on catecholamines such as
CC       adrenaline or noradrenaline than on catechols.
DR   O42898, COMT1_SCHPO;  Q8NKC1, COMT2_SCHPO;  A7MBI7, COMT_BOVIN ;
DR   Q5H879, COMT_HORSE ;  P21964, COMT_HUMAN ;  O88587, COMT_MOUSE ;
DR   Q99028, COMT_PIG   ;  P22734, COMT_RAT   ;  Q8WZ04, TOMT_HUMAN ;
DR   B6CZ46, TOMT_MACMU ;  A1Y9I9, TOMT_MOUSE ;  P86243, TOMT_PANTR ;
DR   B6CZ56, TOMT_PROVC ;  B6CZ62, TOMT_RAT   ;
//
ID   2.1.1.7
DE   Nicotinate N-methyltransferase.
CA   S-adenosyl-L-methionine + nicotinate = S-adenosyl-L-homocysteine +
CA   N-methylnicotinate.
//
ID   2.1.1.8
DE   Histamine N-methyltransferase.
CA   S-adenosyl-L-methionine + histamine = S-adenosyl-L-homocysteine + N(tau)-
CA   methylhistamine.
DR   Q5U4V2, HNMTA_XENLA;  Q7SYS9, HNMTB_XENLA;  Q58DV7, HNMT_BOVIN ;
DR   Q9EST2, HNMT_CAVPO ;  Q6DC37, HNMT_DANRE ;  P50135, HNMT_HUMAN ;
DR   Q91VF2, HNMT_MOUSE ;  Q5R7C3, HNMT_PONAB ;  Q01984, HNMT_RAT   ;
DR   Q4SBY6, HNMT_TETNG ;  Q0V9P1, HNMT_XENTR ;
//
ID   2.1.1.9
DE   Thiol S-methyltransferase.
CA   S-adenosyl-L-methionine + a thiol = S-adenosyl-L-homocysteine +
CA   a thioether.
CC   -!- H(2)S and a variety of alkyl, aryl and heterocyclic thiols and
CC       hydroxy thiols can act as acceptors.
DR   O80562, HOL2_ARATH ;  Q6AWU6, HOL3_ARATH ;
//
ID   2.1.1.10
DE   Homocysteine S-methyltransferase.
CA   S-methyl-L-methionine + L-homocysteine = 2 L-methionine.
CC   -!- The enzyme uses S-adenosyl-L-methionine as methyl donor less actively
CC       than S-methyl-L-methionine.
DR   Q9SDL7, HMT1_ARATH ;  A4ZGQ8, HMT1_BRAOT ;  Q9FUN0, HMT1_MAIZE ;
DR   Q9M1W4, HMT2_ARATH ;  Q9FUM9, HMT2_MAIZE ;  Q8LAX0, HMT3_ARATH ;
DR   Q9FUM8, HMT3_MAIZE ;  Q9FUM7, HMT4_MAIZE ;  O31463, HMT_BACSU  ;
DR   Q12525, MHT1_YEAST ;  Q47690, MMUM_ECOLI ;  Q08985, SAM4_YEAST ;
DR   O06745, YITJ_BACSU ;
//
ID   2.1.1.11
DE   Magnesium protoporphyrin IX methyltransferase.
AN   (-)-S-adenosyl-L-methionine:magnesium-protoporphyrin IX
AN   methyltransferase.
AN   Magnesium-protoporphyrin O-methyltransferase.
AN   Mg-protoporphyrin IX methyltransferase.
AN   S-adenosyl-L-methionine:magnesium-protoporphyrin O-methyltransferase.
AN   S-adenosyl-L-methionine:Mg protoporphyrin methyltransferase.
AN   S-adenosylmethionine-magnesium protoporphyrin methyltransferase.
AN   S-adenosylmethioninemagnesium protoporphyrin methyltransferase.
CA   S-adenosyl-L-methionine + magnesium protoporphyrin IX = S-adenosyl-L-
CA   homocysteine + magnesium protoporphyrin IX 13-methyl ester.
DR   P26236, BCHM_RHOCA ;  Q55467, CHLM_SYNY3 ;
//
ID   2.1.1.12
DE   Methionine S-methyltransferase.
CA   S-adenosyl-L-methionine + L-methionine = S-adenosyl-L-homocysteine +
CA   S-methyl-L-methionine.
CF   Zinc or manganese.
DR   Q9LTB2, MMT1_ARATH ;  Q9MBC2, MMT1_HORVU ;  Q8W519, MMT1_MAIZE ;
DR   Q9SWR3, MMT1_WOLBI ;
//
ID   2.1.1.13
DE   Methionine synthase.
AN   5-methyltetrahydrofolate--homocysteine S-methyltransferase.
AN   5-methyltetrahydrofolate--homocysteine transmethylase.
AN   B12 N(5)-methyltetrahydrofolate homocysteine methyltransferase.
AN   Cobalamin-dependent methionine synthase.
AN   Methionine synthase (cobalamin-dependent).
AN   Methionine synthetase.
AN   Methyltetrahydrofolate--homocysteine vitamin B12 methyltransferase.
AN   N(5)-methyltetrahydrofolate methyltransferase.
AN   N(5)-methyltetrahydrofolate--homocysteine cobalamin methyltransferase.
AN   N(5)-methyltetrahydrofolic--homocysteine vitamin B12 transmethylase.
AN   N-methyltetrahydrofolate:L-homocysteine methyltransferase.
AN   Tetrahydrofolate methyltransferase.
AN   Tetrahydropteroylglutamate methyltransferase.
AN   Tetrahydropteroylglutamic methyltransferase.
AN   Vitamin B12 methyltransferase.
CA   5-methyltetrahydrofolate + L-homocysteine = tetrahydrofolate +
CA   L-methionine.
CF   Cobalamin; Zinc.
CC   -!- The enzyme becomes inactivated occasionally during its cycle by
CC       oxidation of Co(I) to Co(II).
CC   -!- Reactivation by reductive methylation is catalyzed by the enzyme
CC       itself, with S-adenosyl-L-methionine as the methyl donor and a
CC       reducing system.
CC   -!- For the mammalian enzyme, the reducing system involves NADPH and
CC       EC 1.16.1.8.
CC   -!- In bacteria, the reducing agent is flavodoxin, and no further
CC       catalyst is needed (the flavodoxin is kept in the reduced state by
CC       NADPH and EC 1.18.1.2).
CC   -!- Acts on the monoglutamate as well as the triglutamate folate,
CC       in contrast with EC 2.1.1.14, which acts only on the triglutamate.
PR   PROSITE; PDOC50972;
DR   Q4JIJ3, METH_BOVIN ;  A8XY95, METH_CAEBR ;  Q09582, METH_CAEEL ;
DR   Q54P92, METH_DICDI ;  P13009, METH_ECOLI ;  Q99707, METH_HUMAN ;
DR   A6H5Y3, METH_MOUSE ;  Q49775, METH_MYCLE ;  O33259, METH_MYCTU ;
DR   Q9I2Q2, METH_PSEAE ;  O33465, METH_PSEPU ;  Q9Z2Q4, METH_RAT   ;
DR   P37586, METH_SALTY ;  Q55786, METH_SYNY3 ;  Q9KUW9, METH_VIBCH ;
DR   Q5E814, METH_VIBF1 ;  Q9AJQ8, METH_VIBFI ;  Q87L95, METH_VIBPA ;
DR   Q8DCJ7, METH_VIBVU ;  Q7MHB1, METH_VIBVY ;
//
ID   2.1.1.14
DE   5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase.
AN   Cobalamin-independent methionine synthase.
AN   Homocysteine methylase.
AN   Methionine synthase (cobalamin-independent).
AN   Methyltetrahydropteroylpolyglutamate:homocysteine methyltransferase.
AN   Tetrahydropteroylglutamate-homocysteine transmethylase.
CA   5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine =
CA   tetrahydropteroyltri-L-glutamate + L-methionine.
CF   Zinc.
CC   -!- Requires phosphate.
CC   -!- The enzyme from Escherichia coli also requires a reducing system.
CC   -!- Unlike EC 2.1.1.13 this enzyme does not contain cobalamin.
DR   A5G0M4, METE_ACICJ ;  B7J432, METE_ACIF2 ;  B5ELU7, METE_ACIF5 ;
DR   A3N1F9, METE_ACTP2 ;  B3GY43, METE_ACTP7 ;  B0BQ96, METE_ACTPJ ;
DR   A4SNB5, METE_AERS4 ;  Q0VR89, METE_ALCBS ;  Q0A6U0, METE_ALHEH ;
DR   O67606, METE_AQUAE ;  O50008, METE_ARATH ;  A7Z3U1, METE_BACA2 ;
DR   C3P710, METE_BACAA ;  C3LI71, METE_BACAC ;  A0RI12, METE_BACAH ;
DR   Q6KNA9, METE_BACAN ;  B7JKY0, METE_BACC0 ;  Q731W2, METE_BACC1 ;
DR   B7IVP2, METE_BACC2 ;  C1EQ20, METE_BACC3 ;  B7H8Z2, METE_BACC4 ;
DR   B7HMX7, METE_BACC7 ;  A7GS30, METE_BACCN ;  B9IWL4, METE_BACCQ ;
DR   Q819H7, METE_BACCR ;  Q635S6, METE_BACCZ ;  Q9KFP1, METE_BACHD ;
DR   Q6HEG3, METE_BACHK ;  Q65KT8, METE_BACLD ;  A8FCD2, METE_BACP2 ;
DR   P80877, METE_BACSU ;  A9VFA6, METE_BACWK ;  Q1LU68, METE_BAUCH ;
DR   B8DUK6, METE_BIFA0 ;  A1A1F4, METE_BIFAA ;  B3DS65, METE_BIFLD ;
DR   Q8G651, METE_BIFLO ;  B7GRV8, METE_BIFLS ;  Q7VRI8, METE_BLOFL ;
DR   Q491V4, METE_BLOPB ;  Q2KYF3, METE_BORA1 ;  Q7WKM7, METE_BORBR ;
DR   Q7W791, METE_BORPA ;  A9IKD8, METE_BORPD ;  Q7VVU3, METE_BORPE ;
DR   Q9AMV8, METE_BRAJA ;  P57142, METE_BUCAI ;  Q8KA71, METE_BUCAP ;
DR   Q89B24, METE_BUCBP ;  Q058E7, METE_BUCCC ;  B1Z0R8, METE_BURA4 ;
DR   Q1BQX8, METE_BURCA ;  B1K5S8, METE_BURCC ;  A0B2Z3, METE_BURCH ;
DR   B4EJ37, METE_BURCJ ;  Q0B6M7, METE_BURCM ;  A3MHJ9, METE_BURM7 ;
DR   A2S4V8, METE_BURM9 ;  Q62LZ2, METE_BURMA ;  A1V6R3, METE_BURMS ;
DR   A3NY08, METE_BURP0 ;  Q3JPU6, METE_BURP1 ;  A3NC70, METE_BURP6 ;
DR   B2JNZ4, METE_BURP8 ;  B2TBS1, METE_BURPP ;  Q63RX6, METE_BURPS ;
DR   Q39AN3, METE_BURS3 ;  Q2SY55, METE_BURTA ;  A4JJS1, METE_BURVG ;
DR   Q13MI3, METE_BURXL ;  A8FMQ7, METE_CAMJ8 ;  A7H2H6, METE_CAMJD ;
DR   Q9PN94, METE_CAMJE ;  A1W0I5, METE_CAMJJ ;  Q5HTR3, METE_CAMJR ;
DR   P82610, METE_CANAL ;  Q42699, METE_CATRO ;  Q9AAW1, METE_CAUCR ;
DR   Q39586, METE_CHLRE ;  Q1QZS5, METE_CHRSD ;  Q7NS23, METE_CHRVO ;
DR   A8ACX7, METE_CITK8 ;  Q8FQB2, METE_COREF ;  A4QDA4, METE_CORGB ;
DR   Q8NRB3, METE_CORGL ;  B6J6H8, METE_COXB1 ;  B6J3R8, METE_COXB2 ;
DR   A9KDA0, METE_COXBN ;  A9N9C7, METE_COXBR ;  Q83A62, METE_COXBU ;
DR   Q9F187, METE_CUPNE ;  Q0K0V6, METE_CUPNH ;  Q11PV4, METE_CYTH3 ;
DR   A4J5C3, METE_DESRM ;  Q725Q3, METE_DESVH ;  B8DMM2, METE_DESVM ;
DR   Q54X49, METE_DICDI ;  A7ZU36, METE_ECO24 ;  B7MH94, METE_ECO45 ;
DR   Q8X8L5, METE_ECO57 ;  B5YY78, METE_ECO5E ;  B7NV51, METE_ECO7I ;
DR   B7M634, METE_ECO8A ;  B1XAJ3, METE_ECODH ;  A8A6T6, METE_ECOHS ;
DR   A1AHZ7, METE_ECOK1 ;  Q0TAP6, METE_ECOL5 ;  Q8FBM1, METE_ECOL6 ;
DR   B1IW76, METE_ECOLC ;  P25665, METE_ECOLI ;  B7NFD2, METE_ECOLU ;
DR   B6I4H1, METE_ECOSE ;  B1LM00, METE_ECOSM ;  Q1R4A4, METE_ECOUT ;
DR   A4WFZ2, METE_ENT38 ;  A7MQM1, METE_ENTS8 ;  Q6DAS2, METE_ERWCT ;
DR   B2VI65, METE_ERWT9 ;  B7LU25, METE_ESCF3 ;  A5FJR8, METE_FLAJ1 ;
DR   A5UBH4, METE_HAEIE ;  A5UFD9, METE_HAEIG ;  P45331, METE_HAEIN ;
DR   Q0I3P2, METE_HAES1 ;  B0UU16, METE_HAES2 ;  Q2SMS4, METE_HAHCH ;
DR   A9B0A2, METE_HERA2 ;  B5XYJ1, METE_KLEP3 ;  A6TGK9, METE_KLEP7 ;
DR   Q9CG55, METE_LACLA ;  A2RKK4, METE_LACLM ;  Q02YT3, METE_LACLS ;
DR   Q88X63, METE_LACPL ;  Q92AX9, METE_LISIN ;  C1KVY0, METE_LISMC ;
DR   Q71YY6, METE_LISMF ;  Q8Y6K3, METE_LISMO ;  A0AJD5, METE_LISW6 ;
DR   A1TYT7, METE_MARAV ;  P93263, METE_MESCR ;  Q11EU7, METE_MESSB ;
DR   Q605M0, METE_METCA ;  A0QC69, METE_MYCA1 ;  P65341, METE_MYCBO ;
DR   A1KHS4, METE_MYCBP ;  O05564, METE_MYCLE ;  Q73WJ9, METE_MYCPA ;
DR   A5U1I0, METE_MYCTA ;  P65340, METE_MYCTU ;  Q5F863, METE_NEIG1 ;
DR   A9M4E3, METE_NEIM0 ;  Q9JUT6, METE_NEIMA ;  Q9JZQ2, METE_NEIMB ;
DR   A1KTL3, METE_NEIMF ;  Q82UP6, METE_NITEU ;  Q3JAD5, METE_NITOC ;
DR   Q3SNK1, METE_NITWN ;  A7HQP6, METE_PARL1 ;  P57843, METE_PASMU ;
DR   Q3A7E2, METE_PELCD ;  Q7MZ74, METE_PHOLL ;  Q6LSD6, METE_PHOPR ;
DR   P84542, METE_POPEU ;  B4EWC2, METE_PROMH ;  A6V1K5, METE_PSEA7 ;
DR   B7VAU6, METE_PSEA8 ;  Q02L76, METE_PSEAB ;  P57703, METE_PSEAE ;
DR   Q1I4X3, METE_PSEE4 ;  Q4KE22, METE_PSEF5 ;  A4XSY1, METE_PSEMY ;
DR   P85918, METE_PSEMZ ;  B1J2V4, METE_PSEPW ;  Q87XJ9, METE_PSESM ;
DR   A4VNE5, METE_PSEU5 ;  A1T007, METE_PSYIN ;  B2UJ81, METE_RALPJ ;
DR   Q8XS05, METE_RALSO ;  Q98A73, METE_RHILO ;  Q6N765, METE_RHOPA ;
DR   B3QGC4, METE_RHOPT ;  Q0S6X7, METE_RHOSR ;  A1AXN4, METE_RUTMC ;
DR   Q21N29, METE_SACD2 ;  B5EZU1, METE_SALA4 ;  A9MIY8, METE_SALAR ;
DR   Q57HP2, METE_SALCH ;  B5FNW1, METE_SALDC ;  B5QW68, METE_SALEP ;
DR   B5RFN3, METE_SALG2 ;  B4TBQ7, METE_SALHS ;  B4SZ67, METE_SALNS ;
DR   Q5PKP9, METE_SALPA ;  A9MY90, METE_SALPB ;  B5BIX4, METE_SALPK ;
DR   Q2S338, METE_SALRD ;  B4TNX3, METE_SALSV ;  Q8Z3B6, METE_SALTI ;
DR   Q9L6N1, METE_SALTY ;  Q9UT19, METE_SCHPO ;  A8G8B2, METE_SERP5 ;
DR   Q8EIM0, METE_SHEON ;  B2TVH5, METE_SHIB3 ;  Q31UF9, METE_SHIBS ;
DR   Q32A07, METE_SHIDS ;  Q0SZ21, METE_SHIF8 ;  Q83IW0, METE_SHIFL ;
DR   Q3YVD7, METE_SHISS ;  Q2NWV8, METE_SODGM ;  Q42662, METE_SOLSC ;
DR   A7WY46, METE_STAA1 ;  A6TYK8, METE_STAA2 ;  Q2FJQ7, METE_STAA3 ;
DR   Q2G122, METE_STAA8 ;  A5IPT7, METE_STAA9 ;  Q2YVH7, METE_STAAB ;
DR   Q5HIT8, METE_STAAC ;  A6QE38, METE_STAAE ;  P65342, METE_STAAM ;
DR   P65343, METE_STAAN ;  Q6GJW2, METE_STAAR ;  Q6GCB6, METE_STAAS ;
DR   A8YZI1, METE_STAAT ;  Q8NY94, METE_STAAW ;  Q5HS05, METE_STAEQ ;
DR   Q8CMP5, METE_STAES ;  Q4L330, METE_STAHJ ;  Q3JYS3, METE_STRA1 ;
DR   P65344, METE_STRA3 ;  P65345, METE_STRA5 ;  Q82LG4, METE_STRAW ;
DR   Q93J59, METE_STRCO ;  A8AV19, METE_STRGC ;  B1VV57, METE_STRGG ;
DR   Q8CWX6, METE_STRMU ;  Q04LT6, METE_STRP2 ;  B5E298, METE_STRP4 ;
DR   B1IAA7, METE_STRPI ;  Q97S31, METE_STRPN ;  Q8DQT2, METE_STRR6 ;
DR   A3CL11, METE_STRSV ;  A4VXA1, METE_STRSY ;  Q03L46, METE_STRTD ;
DR   Q2JKE8, METE_SYNJB ;  Q8DJY0, METE_THEEB ;  Q9X112, METE_THEMA ;
DR   A5IMS4, METE_THEP1 ;  B1LC63, METE_THESQ ;  B5YJD3, METE_THEYD ;
DR   Q3SGL1, METE_THIDA ;  Q117R7, METE_TRIEI ;  Q9KRD8, METE_VIBCH ;
DR   Q5E430, METE_VIBF1 ;  B5FFR4, METE_VIBFM ;  Q8KRG6, METE_VIBHA ;
DR   A7MRX1, METE_VIBHB ;  Q87NA1, METE_VIBPA ;  Q8CWK1, METE_VIBVU ;
DR   Q7MJM6, METE_VIBVY ;  B2I621, METE_XYLF2 ;  Q9PB72, METE_XYLFA ;
DR   B0U3F5, METE_XYLFM ;  Q87BY8, METE_XYLFT ;  P05694, METE_YEAST ;
DR   A1JIE5, METE_YERE8 ;  A7FDD3, METE_YERP3 ;  Q1CBG7, METE_YERPA ;
DR   Q8ZAL3, METE_YERPE ;  Q1CNC1, METE_YERPN ;  A4TR46, METE_YERPP ;
DR   Q66FT7, METE_YERPS ;
//
ID   2.1.1.15
DE   Fatty-acid O-methyltransferase.
CA   S-adenosyl-L-methionine + a fatty acid = S-adenosyl-L-homocysteine +
CA   a fatty acid methyl ester.
CC   -!- Oleic acid is the most effective fatty acid acceptor.
//
ID   2.1.1.16
DE   Methylene-fatty-acyl-phospholipid synthase.
AN   Cyclopropane synthetase.
AN   Unsaturated-phospholipid methyltransferase.
CA   S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-
CA   L-homocysteine + phospholipid methylene fatty acid.
CC   -!- The enzyme transfers a methyl group to the 10-position of a Delta(9)-
CC       olefinic acyl chain in phosphatidylglycerol, phosphatidylinositol,
CC       or, more slowly, phosphatidylethanolamine; subsequent proton transfer
CC       produces a 10-methylene group (cf. EC 2.1.1.79).
DR   O74827, CHO1_SCHPO ;  Q54SD5, PEM2_DICDI ;  P05375, PEM2_YEAST ;
//
ID   2.1.1.17
DE   Phosphatidylethanolamine N-methyltransferase.
CA   S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-
CA   homocysteine + phosphatidyl-N-methylethanolamine.
DR   A7TNI7, CHO21_VANPO;  A7TLA7, CHO22_VANPO;  C0NLX2, CHO2_AJECG ;
DR   C6H4B5, CHO2_AJECH ;  C5GN10, CHO2_AJEDR ;  C5JCV0, CHO2_AJEDS ;
DR   D4AT37, CHO2_ARTBC ;  C5FZ62, CHO2_ARTOC ;  Q754G0, CHO2_ASHGO ;
DR   A1C7T5, CHO2_ASPCL ;  B0XUW3, CHO2_ASPFC ;  B8N6H2, CHO2_ASPFN ;
DR   Q4WZS1, CHO2_ASPFU ;  A2R616, CHO2_ASPNC ;  Q2UDE5, CHO2_ASPOR ;
DR   Q0CVD7, CHO2_ASPTN ;  A6S950, CHO2_BOTFB ;  Q59LV5, CHO2_CANAL ;
DR   C4YL78, CHO2_CANAW ;  B9WL59, CHO2_CANDC ;  Q6FVB6, CHO2_CANGA ;
DR   C5M4D4, CHO2_CANTT ;  Q2H0U8, CHO2_CHAGB ;  C4Y206, CHO2_CLAL4 ;
DR   C5PEI5, CHO2_COCP7 ;  Q6BY28, CHO2_DEBHA ;  Q5BBC6, CHO2_EMENI ;
DR   Q6CJI9, CHO2_KLULA ;  B0D4E6, CHO2_LACBS ;  C5DGB6, CHO2_LACTC ;
DR   A5DS78, CHO2_LODEL ;  A4RHN5, CHO2_MAGO7 ;  A8PRN6, CHO2_MALGO ;
DR   C7Z7C3, CHO2_NECH7 ;  A1DIF7, CHO2_NEOFI ;  Q7SAJ6, CHO2_NEUCR ;
DR   C1GZK1, CHO2_PARBA ;  C1G565, CHO2_PARBD ;  C0RZV6, CHO2_PARBP ;
DR   B6HJA3, CHO2_PENCW ;  B6QG32, CHO2_PENMQ ;  Q0U2R3, CHO2_PHANO ;
DR   A5DL79, CHO2_PICGU ;  C4QXE9, CHO2_PICPG ;  A3LQW6, CHO2_PICST ;
DR   B2B2N5, CHO2_PODAN ;  B2WFD4, CHO2_PYRTR ;  B6JWP7, CHO2_SCHJY ;
DR   O74787, CHO2_SCHPO ;  D1ZIW5, CHO2_SORMK ;  B8MBN3, CHO2_TALSN ;
DR   D4DGR3, CHO2_TRIVH ;  C4JDF8, CHO2_UNCRE ;  Q6C6U9, CHO2_YARLI ;
DR   B3LI73, CHO2_YEAS1 ;  C7GQ65, CHO2_YEAS2 ;  B5VJA0, CHO2_YEAS6 ;
DR   A6ZUG8, CHO2_YEAS7 ;  C8Z951, CHO2_YEAS8 ;  P05374, CHO2_YEAST ;
DR   C5DZU3, CHO2_ZYGRC ;  Q7YRH6, PEMT_BOVIN ;  Q9UBM1, PEMT_HUMAN ;
DR   Q61907, PEMT_MOUSE ;  Q08388, PEMT_RAT   ;  Q05197, PMTA_RHOSH ;
//
ID   2.1.1.18
DE   Polysaccharide O-methyltransferase.
CA   S-adenosyl-L-methionine + a (1->4)-alpha-D-glucooligosaccharide =
CA   S-adenosyl-L-homocysteine + an oligosaccharide containing 6-methyl-D-
CA   glucose units.
//
ID   2.1.1.19
DE   Trimethylsulfonium--tetrahydrofolate N-methyltransferase.
CA   Trimethylsulfonium + tetrahydrofolate = dimethylsulfide +
CA   5-methyltetrahydrofolate.
//
ID   2.1.1.20
DE   Glycine N-methyltransferase.
AN   Glycine methyltransferase.
CA   S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine +
CA   sarcosine.
CC   -!- Thought to play an important role in the regulation of methyl group
CC       metabolism in the liver and pancreas by regulating the ratio between
CC       S-adenosyl-L-methionine and S-adenosyl-L-homocysteine.
CC   -!- Inhibited by 5-methyltetrahydrofolate pentaglutamate.
CC   -!- Sarcosine, which has no physiological role, is converted back into
CC       glycine by the action of EC 1.5.99.1.
DR   Q14749, GNMT_HUMAN ;  Q9QXF8, GNMT_MOUSE ;  Q29555, GNMT_PIG   ;
DR   Q29513, GNMT_RABIT ;  P13255, GNMT_RAT   ;
//
ID   2.1.1.21
DE   Methylamine--glutamate N-methyltransferase.
AN   N-methylglutamate synthase.
CA   Methylamine + L-glutamate = NH(3) + N-methyl-L-glutamate.
//
ID   2.1.1.22
DE   Carnosine N-methyltransferase.
CA   S-adenosyl-L-methionine + carnosine = S-adenosyl-L-homocysteine +
CA   anserine.
//
ID   2.1.1.23
DE   Transferred entry: 2.1.1.124, 2.1.1.125 and 2.1.1.126.
//
ID   2.1.1.24
DE   Transferred entry: 2.1.1.77, 2.1.1.80 and 2.1.1.100.
//
ID   2.1.1.25
DE   Phenol O-methyltransferase.
CA   S-adenosyl-L-methionine + phenol = S-adenosyl-L-homocysteine + anisole.
CC   -!- Acts on a wide variety of simple alkyl-, methoxy- and halo-phenols.
//
ID   2.1.1.26
DE   Iodophenol O-methyltransferase.
CA   S-adenosyl-L-methionine + 2-iodophenol = S-adenosyl-L-homocysteine +
CA   2-iodophenol methyl ether.
//
ID   2.1.1.27
DE   Tyramine N-methyltransferase.
CA   S-adenosyl-L-methionine + tyramine = S-adenosyl-L-homocysteine +
CA   N-methyltyramine.
CC   -!- Has some activity on phenylethylamine analogs.
//
ID   2.1.1.28
DE   Phenylethanolamine N-methyltransferase.
AN   Noradrenaline N-methyltransferase.
CA   S-adenosyl-L-methionine + phenylethanolamine = S-adenosyl-L-homocysteine
CA   + N-methylphenylethanolamine.
CC   -!- Acts on various phenylethanolamines; converts noradrenaline into
CC       adrenaline.
PR   PROSITE; PDOC00844;
DR   P10938, PNMT_BOVIN ;  P11086, PNMT_HUMAN ;  P40935, PNMT_MOUSE ;
DR   Q06AU9, PNMT_PIG   ;  P10937, PNMT_RAT   ;
//
ID   2.1.1.29
DE   Transferred entry: 2.1.1.202, 2.1.1.203 and 2.1.1.204.
//
ID   2.1.1.30
DE   Deleted entry.
//
ID   2.1.1.31
DE   tRNA (guanine-N(1)-)-methyltransferase.
CA   S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA
CA   containing N(1)-methylguanine.
DR   Q75A17, TRM10_ASHGO;  Q4WXA1, TRM10_ASPFU;  Q59Q39, TRM10_CANAL;
DR   Q6FQB2, TRM10_CANGA;  P0CS11, TRM10_CRYNB;  P0CS10, TRM10_CRYNJ;
DR   Q6BWG3, TRM10_DEBHA;  Q5B8X0, TRM10_EMENI;  Q4I8X0, TRM10_GIBZE;
DR   Q6CUM6, TRM10_KLULA;  Q5JD38, TRM10_PYRKO;  O14214, TRM10_SCHPO;
DR   Q6C1W9, TRM10_YARLI;  Q12400, TRM10_YEAST;  Q9V2G1, TRM5A_PYRAB;
DR   Q58293, TRM5B_METJA;  Q9V0Q0, TRM5B_PYRAB;  Q8TFG7, TRM5_SCHPO ;
DR   P38793, TRM5_YEAST ;  B0CAM2, TRMD_ACAM1 ;  A9NHF7, TRMD_ACHLI ;
DR   A1TND2, TRMD_ACIAC ;  Q43963, TRMD_ACIAD ;  B7GVS0, TRMD_ACIB3 ;
DR   B7IAT0, TRMD_ACIB5 ;  B2HZV3, TRMD_ACIBC ;  Q1IMM4, TRMD_ACIBL ;
DR   B0VQ58, TRMD_ACIBS ;  A3M9G5, TRMD_ACIBT ;  B0V8J1, TRMD_ACIBY ;
DR   A0LV70, TRMD_ACIC1 ;  A3N386, TRMD_ACTP2 ;  B3GZ40, TRMD_ACTP7 ;
DR   B0BSW0, TRMD_ACTPJ ;  A6VLP6, TRMD_ACTSZ ;  A0KG25, TRMD_AERHH ;
DR   A4SIV9, TRMD_AERS4 ;  Q8UBZ7, TRMD_AGRT5 ;  Q0VRF0, TRMD_ALCBS ;
DR   B6EGC1, TRMD_ALISL ;  A6TRS6, TRMD_ALKMQ ;  A8MHC4, TRMD_ALKOO ;
DR   B4RXC7, TRMD_ALTMD ;  B8J893, TRMD_ANAD2 ;  Q2IJ54, TRMD_ANADE ;
DR   A7HBQ1, TRMD_ANADF ;  B9KH73, TRMD_ANAMF ;  Q5P9F9, TRMD_ANAMM ;
DR   Q2GIL5, TRMD_ANAPZ ;  B4UBD2, TRMD_ANASK ;  Q3MC52, TRMD_ANAVT ;
DR   B7GGD9, TRMD_ANOFW ;  O67463, TRMD_AQUAE ;  Q5NXM5, TRMD_AROAE ;
DR   A1R7G3, TRMD_ARTAT ;  B8HA94, TRMD_ARTCA ;  A0JXT9, TRMD_ARTS2 ;
DR   Q2NJG9, TRMD_AYWBP ;  B6YQ31, TRMD_AZOPC ;  A7Z4M3, TRMD_BACA2 ;
DR   C3P5P2, TRMD_BACAA ;  C3L786, TRMD_BACAC ;  A0RHL4, TRMD_BACAH ;
DR   Q81JG7, TRMD_BACAN ;  B7JJS7, TRMD_BACC0 ;  Q732M9, TRMD_BACC1 ;
DR   B7IUK0, TRMD_BACC2 ;  C1EP65, TRMD_BACC3 ;  B7HDW4, TRMD_BACC4 ;
DR   B7HLH4, TRMD_BACC7 ;  B9IVD0, TRMD_BACCQ ;  Q812X2, TRMD_BACCR ;
DR   Q636I5, TRMD_BACCZ ;  Q5LCI1, TRMD_BACFN ;  Q64TM8, TRMD_BACFR ;
DR   Q9KA15, TRMD_BACHD ;  Q6HEX4, TRMD_BACHK ;  Q65JP6, TRMD_BACLD ;
DR   A8FD67, TRMD_BACP2 ;  Q5WFN6, TRMD_BACSK ;  O31741, TRMD_BACSU ;
DR   Q8A9C2, TRMD_BACTN ;  A6L5G9, TRMD_BACV8 ;  A9VT79, TRMD_BACWK ;
DR   A1UR21, TRMD_BARBK ;  Q6G1R9, TRMD_BARHE ;  Q6FYH4, TRMD_BARQU ;
DR   A9IZA2, TRMD_BART1 ;  Q1LTR1, TRMD_BAUCH ;  Q6ML97, TRMD_BDEBA ;
DR   B8DVQ3, TRMD_BIFA0 ;  A0ZZV4, TRMD_BIFAA ;  B3DTR2, TRMD_BIFLD ;
DR   Q8CY56, TRMD_BIFLO ;  B7GMW8, TRMD_BIFLS ;  Q7U345, TRMD_BLOFL ;
DR   Q493M1, TRMD_BLOPB ;  Q2KY83, TRMD_BORA1 ;  Q7U384, TRMD_BORBR ;
DR   O51641, TRMD_BORBU ;  B5RMP3, TRMD_BORDL ;  Q660H3, TRMD_BORGA ;
DR   B2S140, TRMD_BORHD ;  Q7U374, TRMD_BORPA ;  Q7U361, TRMD_BORPE ;
DR   B5RQ39, TRMD_BORRA ;  A1R0C2, TRMD_BORT9 ;  Q89X36, TRMD_BRAJA ;
DR   C0ZFN1, TRMD_BREBN ;  B2S868, TRMD_BRUA1 ;  Q2YLT1, TRMD_BRUA2 ;
DR   Q57AY4, TRMD_BRUAB ;  A9M8Q0, TRMD_BRUC2 ;  C0RFF8, TRMD_BRUMB ;
DR   Q8YJD7, TRMD_BRUME ;  A5VSP1, TRMD_BRUO2 ;  B0CIR8, TRMD_BRUSI ;
DR   Q8CY35, TRMD_BRUSU ;  P57476, TRMD_BUCAI ;  Q8K9F4, TRMD_BUCAP ;
DR   P59518, TRMD_BUCBP ;  B1YV59, TRMD_BURA4 ;  Q1BY02, TRMD_BURCA ;
DR   B1JXU5, TRMD_BURCC ;  A0K5P7, TRMD_BURCH ;  B4EAN4, TRMD_BURCJ ;
DR   Q0BH67, TRMD_BURCM ;  A9ADS9, TRMD_BURM1 ;  A3MHR9, TRMD_BURM7 ;
DR   A2S4N8, TRMD_BURM9 ;  Q62M52, TRMD_BURMA ;  A1V6J2, TRMD_BURMS ;
DR   A3NXU1, TRMD_BURP0 ;  Q3JQ08, TRMD_BURP1 ;  A3NC05, TRMD_BURP6 ;
DR   B2JF31, TRMD_BURP8 ;  B2T605, TRMD_BURPP ;  Q63S32, TRMD_BURPS ;
DR   Q39ID4, TRMD_BURS3 ;  Q2SXZ9, TRMD_BURTA ;  A4JCJ9, TRMD_BURVG ;
DR   Q13VF0, TRMD_BURXL ;  A4XLF1, TRMD_CALS8 ;  A7GZB1, TRMD_CAMC5 ;
DR   A0RPR6, TRMD_CAMFF ;  A7I0V7, TRMD_CAMHC ;  A8FLE2, TRMD_CAMJ8 ;
DR   A7H4B2, TRMD_CAMJD ;  Q9PPJ4, TRMD_CAMJE ;  A1VZ68, TRMD_CAMJJ ;
DR   Q5HV68, TRMD_CAMJR ;  Q3AC72, TRMD_CARHZ ;  Q9ABM9, TRMD_CAUCR ;
DR   A9WDJ3, TRMD_CHLAA ;  Q5L5L8, TRMD_CHLAB ;  B8G9R8, TRMD_CHLAD ;
DR   Q3ASF7, TRMD_CHLCH ;  Q820E4, TRMD_CHLCV ;  Q255B1, TRMD_CHLFF ;
DR   Q9PL12, TRMD_CHLMU ;  Q9Z964, TRMD_CHLPN ;  B9LI79, TRMD_CHLSY ;
DR   B0B9D4, TRMD_CHLT2 ;  B3QXJ6, TRMD_CHLT3 ;  Q3KMZ5, TRMD_CHLTA ;
DR   B0BB13, TRMD_CHLTB ;  Q8KD90, TRMD_CHLTE ;  O84030, TRMD_CHLTR ;
DR   Q1QT50, TRMD_CHRSD ;  Q7MBD6, TRMD_CHRVO ;  A5CQR1, TRMD_CLAM3 ;
DR   B0REN1, TRMD_CLAMS ;  Q97I94, TRMD_CLOAB ;  A7FW09, TRMD_CLOB1 ;
DR   C3L0E3, TRMD_CLOB6 ;  A6LSN1, TRMD_CLOB8 ;  B2V4E5, TRMD_CLOBA ;
DR   B2TJ31, TRMD_CLOBB ;  A5I4M3, TRMD_CLOBH ;  C1FSL5, TRMD_CLOBJ ;
DR   B1II76, TRMD_CLOBK ;  A7GG33, TRMD_CLOBL ;  B1KWN5, TRMD_CLOBM ;
DR   B8I7T5, TRMD_CLOCE ;  Q18BC2, TRMD_CLOD6 ;  B9E1H7, TRMD_CLOK1 ;
DR   A5N816, TRMD_CLOK5 ;  A0Q0Y0, TRMD_CLONN ;  Q0TPP4, TRMD_CLOP1 ;
DR   Q8XJP7, TRMD_CLOPE ;  A9KLM2, TRMD_CLOPH ;  Q0SSB1, TRMD_CLOPS ;
DR   Q895M2, TRMD_CLOTE ;  Q47WV0, TRMD_COLP3 ;  B5Y8F3, TRMD_COPPD ;
DR   C3PH72, TRMD_CORA7 ;  Q6NGI5, TRMD_CORDI ;  Q8CY26, TRMD_COREF ;
DR   Q8NNX7, TRMD_CORGL ;  Q4JV03, TRMD_CORJK ;  B6J8J0, TRMD_COXB1 ;
DR   B6J1N4, TRMD_COXB2 ;  A9KEE9, TRMD_COXBN ;  A9NBQ9, TRMD_COXBR ;
DR   Q820X1, TRMD_COXBU ;  Q0KD79, TRMD_CUPNH ;  Q46Y84, TRMD_CUPPJ ;
DR   B3R398, TRMD_CUPTR ;  B1WPL5, TRMD_CYAA5 ;  B8HMF0, TRMD_CYAP4 ;
DR   B7KHC2, TRMD_CYAP7 ;  Q11YV4, TRMD_CYTH3 ;  Q47BI7, TRMD_DECAR ;
DR   Q3Z9L3, TRMD_DEHE1 ;  A5FSB5, TRMD_DEHSB ;  Q3ZZA6, TRMD_DEHSC ;
DR   C1CUT8, TRMD_DEIDV ;  Q1IYA3, TRMD_DEIGD ;  Q9RSW0, TRMD_DEIRA ;
DR   B8FNP3, TRMD_DESAA ;  B1I2N1, TRMD_DESAP ;  Q313J9, TRMD_DESDG ;
DR   Q24UA9, TRMD_DESHY ;  Q6AJE8, TRMD_DESPS ;  A4J665, TRMD_DESRM ;
DR   Q72DU3, TRMD_DESVH ;  B5YFD5, TRMD_DICT6 ;  B8E2G4, TRMD_DICTD ;
DR   A7ZQ47, TRMD_ECO24 ;  B7UH56, TRMD_ECO27 ;  B7MIU5, TRMD_ECO45 ;
DR   B7LDJ6, TRMD_ECO55 ;  P0A875, TRMD_ECO57 ;  B5Z226, TRMD_ECO5E ;
DR   B7NSA6, TRMD_ECO7I ;  B7MYA0, TRMD_ECO81 ;  B7M976, TRMD_ECO8A ;
DR   C4ZYM5, TRMD_ECOBW ;  B1XBS9, TRMD_ECODH ;  A8A3B4, TRMD_ECOHS ;
DR   Q0TEN2, TRMD_ECOL5 ;  P0A874, TRMD_ECOL6 ;  B1IVM6, TRMD_ECOLC ;
DR   P0A873, TRMD_ECOLI ;  B7N6J3, TRMD_ECOLU ;  B6I629, TRMD_ECOSE ;
DR   B1LPB4, TRMD_ECOSM ;  Q1R8B8, TRMD_ECOUT ;  C5BGG0, TRMD_EDWI9 ;
DR   Q3YQP3, TRMD_EHRCJ ;  Q2GI95, TRMD_EHRCR ;  Q5FGP5, TRMD_EHRRG ;
DR   Q5H9Z7, TRMD_EHRRW ;  A4WDH2, TRMD_ENT38 ;  Q820U3, TRMD_ENTFA ;
DR   A7MEG4, TRMD_ENTS8 ;  Q6D1U0, TRMD_ERWCT ;  B7LUW6, TRMD_ESCF3 ;
DR   C4Z429, TRMD_EUBE2 ;  B1YIM4, TRMD_EXIS2 ;  C4L603, TRMD_EXISA ;
DR   A7HKS1, TRMD_FERNB ;  B0S047, TRMD_FINM2 ;  A5FHV7, TRMD_FLAJ1 ;
DR   A6H0R6, TRMD_FLAPJ ;  Q0RDP4, TRMD_FRAAA ;  B0TX18, TRMD_FRAP2 ;
DR   Q2J6Z9, TRMD_FRASC ;  A8L5A5, TRMD_FRASN ;  Q14JS7, TRMD_FRAT1 ;
DR   A7NEB1, TRMD_FRATF ;  Q2A1N5, TRMD_FRATH ;  B2SFE4, TRMD_FRATM ;
DR   A0Q859, TRMD_FRATN ;  Q5NIC4, TRMD_FRATT ;  A4IWA7, TRMD_FRATW ;
DR   Q8R5Y4, TRMD_FUSNN ;  B5EBC9, TRMD_GEOBB ;  Q5L0P4, TRMD_GEOKA ;
DR   Q39RN8, TRMD_GEOMG ;  B9M594, TRMD_GEOSF ;  Q74FG3, TRMD_GEOSL ;
DR   C6E5I8, TRMD_GEOSM ;  A5G7Z5, TRMD_GEOUR ;  Q7MBC8, TRMD_GLOVI ;
DR   A9HS61, TRMD_GLUDA ;  Q5FUG1, TRMD_GLUOX ;  A0LZ03, TRMD_GRAFK ;
DR   Q7U331, TRMD_HAEDU ;  Q4QNY8, TRMD_HAEI8 ;  A5UAV3, TRMD_HAEIE ;
DR   A5UG04, TRMD_HAEIG ;  P43912, TRMD_HAEIN ;  B8F7X3, TRMD_HAEPS ;
DR   Q0I1J8, TRMD_HAES1 ;  B0UVM8, TRMD_HAES2 ;  Q2SL56, TRMD_HAHCH ;
DR   A1WUF3, TRMD_HALHL ;  B8CW21, TRMD_HALOH ;  Q7U321, TRMD_HELHP ;
DR   B0TH67, TRMD_HELMI ;  Q9ZK66, TRMD_HELPJ ;  B2UUQ7, TRMD_HELPS ;
DR   O25766, TRMD_HELPY ;  A9B3P8, TRMD_HERA2 ;  A4G2T7, TRMD_HERAR ;
DR   Q5QUV0, TRMD_IDILO ;  A6SVI6, TRMD_JANMA ;  Q28UF1, TRMD_JANSC ;
DR   A6W7V0, TRMD_KINRD ;  B5XVK5, TRMD_KLEP3 ;  A6TCL5, TRMD_KLEP7 ;
DR   B2GFY4, TRMD_KOCRD ;  Q5FJK7, TRMD_LACAC ;  Q03RU7, TRMD_LACBA ;
DR   Q038K0, TRMD_LACC3 ;  B3WEU0, TRMD_LACCB ;  Q1G9L4, TRMD_LACDA ;
DR   Q049R8, TRMD_LACDB ;  B2GD25, TRMD_LACF3 ;  A8YVT2, TRMD_LACH4 ;
DR   Q74IQ6, TRMD_LACJO ;  Q9CFB7, TRMD_LACLA ;  Q88WJ2, TRMD_LACPL ;
DR   A5VKN4, TRMD_LACRD ;  B2G818, TRMD_LACRJ ;  Q1WU92, TRMD_LACS1 ;
DR   Q38XQ7, TRMD_LACSS ;  C1DBG0, TRMD_LARHH ;  Q5X7Z1, TRMD_LEGPA ;
DR   Q5ZYH6, TRMD_LEGPH ;  Q5WZE2, TRMD_LEGPL ;  Q6AEA3, TRMD_LEIXX ;
DR   Q04SW4, TRMD_LEPBJ ;  Q050Y8, TRMD_LEPBL ;  B1Y0H7, TRMD_LEPCP ;
DR   Q72S28, TRMD_LEPIC ;  Q8CXS8, TRMD_LEPIN ;  B1MZT4, TRMD_LEUCK ;
DR   Q03W52, TRMD_LEUMM ;  Q92AL6, TRMD_LISIN ;  C1KW91, TRMD_LISMC ;
DR   Q71YM4, TRMD_LISMF ;  B8DDW1, TRMD_LISMH ;  Q8Y6A3, TRMD_LISMO ;
DR   A0AJP7, TRMD_LISW6 ;  B9EBB9, TRMD_MACCJ ;  Q2VZV6, TRMD_MAGSA ;
DR   A0L4Y8, TRMD_MAGSM ;  Q65VG1, TRMD_MANSM ;  A6W1U0, TRMD_MARMS ;
DR   Q6F0S5, TRMD_MESFL ;  Q11CR0, TRMD_MESSB ;  Q60BS1, TRMD_METCA ;
DR   Q1GYT8, TRMD_METFK ;  B3DVH5, TRMD_METI4 ;  A2SES8, TRMD_METPP ;
DR   B0JJC4, TRMD_MICAN ;  C5CAH0, TRMD_MICLC ;  Q2RJV4, TRMD_MOOTA ;
DR   B3PMA2, TRMD_MYCA5 ;  A5IZ67, TRMD_MYCAP ;  P66969, TRMD_MYCBO ;
DR   A1KMQ0, TRMD_MYCBP ;  C1AG21, TRMD_MYCBT ;  Q2SRU7, TRMD_MYCCT ;
DR   Q9RDV3, TRMD_MYCGA ;  P47683, TRMD_MYCGE ;  Q601V6, TRMD_MYCH2 ;
DR   Q4A880, TRMD_MYCH7 ;  Q4AA53, TRMD_MYCHJ ;  O33017, TRMD_MYCLE ;
DR   Q6KHL5, TRMD_MYCMO ;  Q6MTI1, TRMD_MYCMS ;  Q73VN9, TRMD_MYCPA ;
DR   Q8CXQ6, TRMD_MYCPE ;  P75132, TRMD_MYCPN ;  Q98Q98, TRMD_MYCPU ;
DR   Q4A738, TRMD_MYCS5 ;  A5U6R1, TRMD_MYCTA ;  P66968, TRMD_MYCTU ;
DR   Q1D6I2, TRMD_MYXXD ;  B2A2P2, TRMD_NATTJ ;  Q5FA59, TRMD_NEIG1 ;
DR   B4RIW3, TRMD_NEIG2 ;  A9M2D1, TRMD_NEIM0 ;  Q9JVL0, TRMD_NEIMA ;
DR   Q9K0K4, TRMD_NEIMB ;  A1KSJ9, TRMD_NEIMF ;  Q2GCN4, TRMD_NEOSM ;
DR   Q820K4, TRMD_NITEU ;  Q1QHI7, TRMD_NITHX ;  Q2YBJ2, TRMD_NITMU ;
DR   Q3J8Y0, TRMD_NITOC ;  A6Q549, TRMD_NITSB ;  Q3SNV6, TRMD_NITWN ;
DR   Q5YS38, TRMD_NOCFA ;  B2JA48, TRMD_NOSP7 ;  Q8YQF1, TRMD_NOSS1 ;
DR   Q2G8H2, TRMD_NOVAD ;  Q8CXH3, TRMD_OCEIH ;  Q04FP5, TRMD_OENOB ;
DR   Q6YQA4, TRMD_ONYPE ;  Q6MDG9, TRMD_PARUW ;  Q9CLE1, TRMD_PASMU ;
DR   C6DCP9, TRMD_PECCP ;  Q03FW3, TRMD_PEDPA ;  Q3A2E7, TRMD_PELCD ;
DR   Q3B4A1, TRMD_PELLD ;  A5D1J4, TRMD_PELTS ;  Q4FP13, TRMD_PELUB ;
DR   C0QQJ9, TRMD_PERMH ;  Q7MB64, TRMD_PHOLL ;  Q6LMV9, TRMD_PHOPR ;
DR   B1VAA9, TRMD_PHYAS ;  B3R0P2, TRMD_PHYMT ;  B1XVN1, TRMD_POLNS ;
DR   Q12CW4, TRMD_POLSJ ;  A4SW75, TRMD_POLSQ ;  B2RMA5, TRMD_PORG3 ;
DR   Q7MAV4, TRMD_PORGI ;  Q6A7S7, TRMD_PROAC ;  A8G690, TRMD_PROM2 ;
DR   Q319K9, TRMD_PROM9 ;  B4EUW6, TRMD_PROMH ;  Q48LV8, TRMD_PSE14 ;
DR   Q15VI7, TRMD_PSEA6 ;  A6V125, TRMD_PSEA7 ;  B7UYK8, TRMD_PSEA8 ;
DR   Q02RL6, TRMD_PSEAB ;  Q9HXQ1, TRMD_PSEAE ;  Q1I5Z0, TRMD_PSEE4 ;
DR   Q4KHQ6, TRMD_PSEF5 ;  C3K1G9, TRMD_PSEFS ;  Q3IEC7, TRMD_PSEHT ;
DR   A5W8C1, TRMD_PSEP1 ;  Q3KHJ2, TRMD_PSEPF ;  B0KRI3, TRMD_PSEPG ;
DR   Q88MV4, TRMD_PSEPK ;  B1JDE3, TRMD_PSEPW ;  Q886V0, TRMD_PSESM ;
DR   Q4ZWY7, TRMD_PSEU2 ;  A4VIT7, TRMD_PSEU5 ;  Q4FQ44, TRMD_PSYA2 ;
DR   Q1Q8A6, TRMD_PSYCK ;  A1SZY6, TRMD_PSYIN ;  A5WBX0, TRMD_PSYWF ;
DR   Q1LQE0, TRMD_RALME ;  Q8Y0V8, TRMD_RALSO ;  A9WP47, TRMD_RENSM ;
DR   Q2K380, TRMD_RHIEC ;  Q1MAK3, TRMD_RHIL3 ;  Q98EE1, TRMD_RHILO ;
DR   Q92L41, TRMD_RHIME ;  Q7TTY8, TRMD_RHOBA ;  Q21YL6, TRMD_RHOFD ;
DR   Q2J399, TRMD_RHOP2 ;  Q6ND67, TRMD_RHOPA ;  Q21CT7, TRMD_RHOPB ;
DR   B3Q854, TRMD_RHOPT ;  Q2RV57, TRMD_RHORT ;  Q3IZ05, TRMD_RHOS4 ;
DR   B9KNX7, TRMD_RHOSK ;  Q0S2C5, TRMD_RHOSR ;  C3PME7, TRMD_RICAE ;
DR   A8GM73, TRMD_RICAH ;  Q1RH66, TRMD_RICBR ;  Q92JB6, TRMD_RICCN ;
DR   Q4UNA8, TRMD_RICFE ;  Q9ZE37, TRMD_RICPR ;  C4K1C8, TRMD_RICPU ;
DR   B0BW78, TRMD_RICRO ;  A8GQT2, TRMD_RICRS ;  Q68XX9, TRMD_RICTY ;
DR   Q16AP1, TRMD_ROSDO ;  Q21LG2, TRMD_SACD2 ;  A4FME8, TRMD_SACEN ;
DR   B5F287, TRMD_SALA4 ;  A8M680, TRMD_SALAI ;  Q57L31, TRMD_SALCH ;
DR   B5FS07, TRMD_SALDC ;  B5QUG2, TRMD_SALEP ;  B5RD83, TRMD_SALG2 ;
DR   B4TE51, TRMD_SALHS ;  B4T2B3, TRMD_SALNS ;  Q5PFF8, TRMD_SALPA ;
DR   C0PW17, TRMD_SALPC ;  B5BE92, TRMD_SALPK ;  Q2S234, TRMD_SALRD ;
DR   B4TS54, TRMD_SALSV ;  Q8Z4I5, TRMD_SALTI ;  A4X4H8, TRMD_SALTO ;
DR   P36245, TRMD_SALTY ;  P36244, TRMD_SERMA ;  A8GA20, TRMD_SERP5 ;
DR   A1S3Z2, TRMD_SHEAM ;  B8EBP1, TRMD_SHEB2 ;  A3D1W7, TRMD_SHEB5 ;
DR   A6WKR8, TRMD_SHEB8 ;  A9L5P7, TRMD_SHEB9 ;  Q12KJ5, TRMD_SHEDO ;
DR   Q07Z07, TRMD_SHEFN ;  B0TJ77, TRMD_SHEHH ;  A3QBT8, TRMD_SHELP ;
DR   Q8CX44, TRMD_SHEON ;  A8H1E1, TRMD_SHEPA ;  A4Y4L5, TRMD_SHEPC ;
DR   B8CQI2, TRMD_SHEPW ;  A0KZM1, TRMD_SHESA ;  A8FSE9, TRMD_SHESH ;
DR   Q0HGB0, TRMD_SHESM ;  Q0HSK3, TRMD_SHESR ;  A1RMB6, TRMD_SHESW ;
DR   B1KI70, TRMD_SHEWM ;  B2TYM9, TRMD_SHIB3 ;  Q31XD8, TRMD_SHIBS ;
DR   Q32CY1, TRMD_SHIDS ;  Q0T175, TRMD_SHIF8 ;  P0A876, TRMD_SHIFL ;
DR   Q3YYN1, TRMD_SHISS ;  Q5LNE6, TRMD_SILPO ;  Q1GDC3, TRMD_SILST ;
DR   Q2NVK2, TRMD_SODGM ;  A9F3N2, TRMD_SORC5 ;  Q1GPJ7, TRMD_SPHAL ;
DR   A5V9Q2, TRMD_SPHWW ;  Q6XYU1, TRMD_SPIKU ;  A7X1L0, TRMD_STAA1 ;
DR   A6U159, TRMD_STAA2 ;  Q2FHJ8, TRMD_STAA3 ;  Q2FZ43, TRMD_STAA8 ;
DR   A5ISC5, TRMD_STAA9 ;  Q2YXM5, TRMD_STAAB ;  Q5HGJ2, TRMD_STAAC ;
DR   A6QGE0, TRMD_STAAE ;  P66970, TRMD_STAAM ;  P66971, TRMD_STAAN ;
DR   Q6GHJ5, TRMD_STAAR ;  Q6G9X3, TRMD_STAAS ;  Q8NX06, TRMD_STAAW ;
DR   B9DPK1, TRMD_STACT ;  Q5HPV1, TRMD_STAEQ ;  Q8CQL4, TRMD_STAES ;
DR   Q4L5U2, TRMD_STAHJ ;  Q49X26, TRMD_STAS1 ;  Q3K0F8, TRMD_STRA1 ;
DR   Q8E4H7, TRMD_STRA3 ;  Q8CX07, TRMD_STRA5 ;  Q82JW3, TRMD_STRAW ;
DR   P0A4P1, TRMD_STRCO ;  C0M748, TRMD_STRE4 ;  B4U395, TRMD_STREM ;
DR   A8AXT6, TRMD_STRGC ;  P0A4P2, TRMD_STRLI ;  B4SPH3, TRMD_STRM5 ;
DR   B2FUB5, TRMD_STRMK ;  Q8DUN6, TRMD_STRMU ;  Q9A0B6, TRMD_STRP1 ;
DR   Q04LC5, TRMD_STRP2 ;  P0DG20, TRMD_STRP3 ;  B5E3G1, TRMD_STRP4 ;
DR   Q5XCQ3, TRMD_STRP6 ;  C1C6C0, TRMD_STRP7 ;  Q8P1F3, TRMD_STRP8 ;
DR   Q1JMB3, TRMD_STRPC ;  Q1JHF6, TRMD_STRPD ;  Q1J777, TRMD_STRPF ;
DR   A2RF48, TRMD_STRPG ;  B1IAV3, TRMD_STRPI ;  B8ZND2, TRMD_STRPJ ;
DR   Q48U55, TRMD_STRPM ;  Q97RM4, TRMD_STRPN ;  P0DG21, TRMD_STRPQ ;
DR   B2INF6, TRMD_STRPS ;  Q8CWS4, TRMD_STRR6 ;  A4W0T9, TRMD_STRS2 ;
DR   C0MEI3, TRMD_STRS7 ;  A3CNE6, TRMD_STRSV ;  A4VUJ7, TRMD_STRSY ;
DR   Q5LYY2, TRMD_STRT1 ;  Q5M3J5, TRMD_STRT2 ;  Q03JS1, TRMD_STRTD ;
DR   B9DRW6, TRMD_STRU0 ;  C1CDC7, TRMD_STRZJ ;  C1CJM5, TRMD_STRZP ;
DR   C1CSA6, TRMD_STRZT ;  Q30TE6, TRMD_SULDN ;  A6Q772, TRMD_SULNB ;
DR   B2V6N2, TRMD_SULSY ;  Q67PD8, TRMD_SYMTH ;  Q2LVU2, TRMD_SYNAS ;
DR   Q31L04, TRMD_SYNE7 ;  Q2JTR0, TRMD_SYNJA ;  Q2JM55, TRMD_SYNJB ;
DR   Q5N0W7, TRMD_SYNP6 ;  A5GMI5, TRMD_SYNPW ;  A5GUS1, TRMD_SYNR3 ;
DR   Q0IC33, TRMD_SYNS3 ;  Q0AWV7, TRMD_SYNWW ;  P72828, TRMD_SYNY3 ;
DR   B7IEQ5, TRMD_THEAB ;  Q8CWM2, TRMD_THEEB ;  Q47S64, TRMD_THEFY ;
DR   A6LNY6, TRMD_THEM4 ;  Q9X1Q5, TRMD_THEMA ;  A5IM14, TRMD_THEP1 ;
DR   B9KXN9, TRMD_THERP ;  B1LB78, TRMD_THESQ ;  Q72JU8, TRMD_THET2 ;
DR   Q5SJH6, TRMD_THET8 ;  Q8R5S2, TRMD_THETN ;  B5YK96, TRMD_THEYD ;
DR   Q31HX8, TRMD_THICR ;  Q3SGC2, TRMD_THIDA ;  C4LD25, TRMD_TOLAT ;
DR   Q73PB5, TRMD_TREDE ;  O83878, TRMD_TREPA ;  Q113W0, TRMD_TRIEI ;
DR   Q820Z0, TRMD_TROW8 ;  Q820Y0, TRMD_TROWT ;  B1GZ20, TRMD_UNCTG ;
DR   B1AJK8, TRMD_UREP2 ;  Q9PPS2, TRMD_UREPA ;  B5ZC78, TRMD_UREU1 ;
DR   A5F9A9, TRMD_VIBC3 ;  Q9KUF8, TRMD_VIBCH ;  C3LS53, TRMD_VIBCM ;
DR   Q5E7F0, TRMD_VIBF1 ;  B5FAE7, TRMD_VIBFM ;  A7MYV2, TRMD_VIBHB ;
DR   Q87LT0, TRMD_VIBPA ;  B7VK27, TRMD_VIBSL ;  Q8CWK5, TRMD_VIBVU ;
DR   Q7M7J0, TRMD_VIBVY ;  Q73GD5, TRMD_WOLPM ;  B3CM65, TRMD_WOLPP ;
DR   Q7MA04, TRMD_WOLSU ;  Q5GT55, TRMD_WOLTR ;  C0R443, TRMD_WOLWR ;
DR   Q8PMY1, TRMD_XANAC ;  Q3BVY8, TRMD_XANC5 ;  Q4US84, TRMD_XANC8 ;
DR   B0RXD7, TRMD_XANCB ;  Q8PBC1, TRMD_XANCP ;  Q2P651, TRMD_XANOM ;
DR   B2SJV1, TRMD_XANOP ;  Q5H390, TRMD_XANOR ;  B2I6A8, TRMD_XYLF2 ;
DR   Q9PH37, TRMD_XYLFA ;  Q87F54, TRMD_XYLFT ;  A1JK25, TRMD_YERE8 ;
DR   A7FLQ5, TRMD_YERP3 ;  Q1C409, TRMD_YERPA ;  B2K5Z0, TRMD_YERPB ;
DR   Q8ZBU9, TRMD_YERPE ;  A9R0U3, TRMD_YERPG ;  Q1CLJ3, TRMD_YERPN ;
DR   A4TQ64, TRMD_YERPP ;  Q66E57, TRMD_YERPS ;  B1JJ89, TRMD_YERPY ;
DR   Q5NNK8, TRMD_ZYMMO ;  Q3MHN8, TRMT5_BOVIN;  Q32P41, TRMT5_HUMAN;
DR   Q95KJ2, TRMT5_MACFA;  Q9D0C4, TRMT5_MOUSE;
//
ID   2.1.1.32
DE   tRNA (guanine-N(2)-)-methyltransferase.
AN   N(2),N(2)-dimethylguanine tRNA methyltransferase.
AN   tRNA 2,2-dimethylguanosine-26 methyltransferase.
AN   tRNA(guanine-26,N(2)-N(2)) methyltransferase.
AN   tRNA(m(2,2)G26)dimethyltransferase.
CA   S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA
CA   containing N(2)-methylguanine.
CC   -!- In eukaryotic tRNAs, two N(2)-guanine methylations occur, at the
CC       N(2)-methylguanine at position 10 and the N(2)-methylguanine at
CC       position 29.
DR   O29011, TMG10_ARCFU;  Q58120, TMG10_METJA;  O26820, TMG10_METTH;
DR   P05409, TMG10_METTL;  Q9UY84, TMG10_PYRAB;  Q9YDY7, TRM1_AERPE ;
DR   O67010, TRM1_AQUAE ;  Q9LFU5, TRM1_ARATH ;  O29443, TRM1_ARCFU ;
DR   Q23270, TRM1_CAEEL ;  Q9VK89, TRM1_DROME ;  Q8SR99, TRM1_ENCCU ;
DR   B9LSI7, TRM1_HALLT ;  Q5UYV8, TRM1_HALMA ;  B0R713, TRM1_HALS3 ;
DR   P57705, TRM1_HALSA ;  Q18EA0, TRM1_HALWD ;  Q9NXH9, TRM1_HUMAN ;
DR   A6UUN6, TRM1_META3 ;  Q8TGX6, TRM1_METAC ;  A7I9E9, TRM1_METB6 ;
DR   Q466T6, TRM1_METBF ;  Q12Y46, TRM1_METBU ;  Q2FN43, TRM1_METHJ ;
DR   Q58356, TRM1_METJA ;  Q8TYY7, TRM1_METKA ;  A2SRK9, TRM1_METLZ ;
DR   A4FZY5, TRM1_METM5 ;  A9A871, TRM1_METM6 ;  A6VIL5, TRM1_METM7 ;
DR   Q8PU28, TRM1_METMA ;  P0CW64, TRM1_METMI ;  A3CW75, TRM1_METMJ ;
DR   P0CW65, TRM1_METMP ;  B8GF12, TRM1_METPE ;  A5UM08, TRM1_METS3 ;
DR   A4YHH9, TRM1_METS5 ;  Q2NI56, TRM1_METST ;  O27258, TRM1_METTH ;
DR   Q3TX08, TRM1_MOUSE ;  Q3IUJ2, TRM1_NATPD ;  Q9V1P3, TRM1_PYRAB ;
DR   Q8ZWT5, TRM1_PYRAE ;  A4WMB7, TRM1_PYRAR ;  A3MTQ5, TRM1_PYRCJ ;
DR   P81554, TRM1_PYRFU ;  O59493, TRM1_PYRHO ;  A1RV26, TRM1_PYRIL ;
DR   Q5JIB3, TRM1_PYRKO ;  P20300, TRM1_PYRWO ;  Q9P804, TRM1_SCHPO ;
DR   Q4J947, TRM1_SULAC ;  C3N5E1, TRM1_SULIA ;  C4KH07, TRM1_SULIK ;
DR   C3MPR5, TRM1_SULIL ;  C3MYQ9, TRM1_SULIM ;  C3NHQ8, TRM1_SULIN ;
DR   C3NDZ5, TRM1_SULIY ;  Q97ZH0, TRM1_SULSO ;  Q971V9, TRM1_SULTO ;
DR   P57706, TRM1_THEAC ;  C5A6N2, TRM1_THEGJ ;  B1YCV9, TRM1_THENV ;
DR   B6YUU9, TRM1_THEON ;  Q97AR2, TRM1_THEVO ;  P15565, TRM1_YEAST ;
DR   Q9SRU7, TRM2_ARATH ;
//
ID   2.1.1.33
DE   tRNA (guanine-N(7)-)-methyltransferase.
CA   S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA
CA   containing N(7)-methylguanine.
DR   Q1RH40, HEMK_RICBR ;  Q92G13, HEMK_RICCN ;  Q4UJU4, HEMK_RICFE ;
DR   Q9ZCB3, HEMK_RICPR ;  Q68VR6, HEMK_RICTY ;  Q28H76, TRMBA_XENTR;
DR   A9UMM1, TRMBB_XENTR;  A1TRL2, TRMB_ACIAC ;  Q6FCN6, TRMB_ACIAD ;
DR   B7J415, TRMB_ACIF2 ;  A1W7D2, TRMB_ACISJ ;  A3N231, TRMB_ACTP2 ;
DR   A6VLR7, TRMB_ACTSZ ;  Q0IEN3, TRMB_AEDAE ;  A0KNV5, TRMB_AERHH ;
DR   Q8UID4, TRMB_AGRT5 ;  Q0VLC7, TRMB_ALCBS ;  Q0ACP5, TRMB_ALHEH ;
DR   B6EMU1, TRMB_ALISL ;  A6TMJ6, TRMB_ALKMQ ;  A8MIM4, TRMB_ALKOO ;
DR   Q2IG43, TRMB_ANADE ;  Q3M3Q5, TRMB_ANAVT ;  Q7Q2P7, TRMB_ANOGA ;
DR   O66479, TRMB_AQUAE ;  Q8GXB7, TRMB_ARATH ;  Q8G9C6, TRMB_AROAE ;
DR   A1RAI8, TRMB_ARTAT ;  A0K1I7, TRMB_ARTS2 ;  Q74ZK8, TRMB_ASHGO ;
DR   A1CIF1, TRMB_ASPCL ;  B0Y4I9, TRMB_ASPFC ;  Q4WQB9, TRMB_ASPFU ;
DR   A2Q9E4, TRMB_ASPNC ;  Q2UU72, TRMB_ASPOR ;  Q0CT71, TRMB_ASPTN ;
DR   A8IG13, TRMB_AZOC5 ;  A1KCM8, TRMB_AZOSB ;  A7Z7T3, TRMB_BACA2 ;
DR   C3PBG1, TRMB_BACAA ;  C3LA04, TRMB_BACAC ;  A0RJT7, TRMB_BACAH ;
DR   P59716, TRMB_BACAN ;  B7JS74, TRMB_BACC0 ;  Q72Z28, TRMB_BACC1 ;
DR   B7IKW6, TRMB_BACC2 ;  C1EVW6, TRMB_BACC3 ;  B7H758, TRMB_BACC4 ;
DR   B7HSN5, TRMB_BACC7 ;  A7GTW9, TRMB_BACCN ;  B9J1A0, TRMB_BACCQ ;
DR   P59717, TRMB_BACCR ;  Q632Z1, TRMB_BACCZ ;  Q5L8Y2, TRMB_BACFN ;
DR   Q64P45, TRMB_BACFR ;  Q9K7U8, TRMB_BACHD ;  Q6HCI1, TRMB_BACHK ;
DR   Q65G12, TRMB_BACLD ;  Q5WE98, TRMB_BACSK ;  O34522, TRMB_BACSU ;
DR   Q8A0X7, TRMB_BACTN ;  A9VKK9, TRMB_BACWK ;  A1UU46, TRMB_BARBK ;
DR   Q6G4W3, TRMB_BARHE ;  Q6G0N8, TRMB_BARQU ;  Q6MQU0, TRMB_BDEBA ;
DR   A1A0E0, TRMB_BIFAA ;  Q8G3T4, TRMB_BIFLO ;  B7GP38, TRMB_BIFLS ;
DR   Q1HPU2, TRMB_BOMMO ;  Q2KYW5, TRMB_BORA1 ;  Q7WQ22, TRMB_BORBR ;
DR   Q7WC23, TRMB_BORPA ;  Q7VT61, TRMB_BORPE ;  A6S8E7, TRMB_BOTFB ;
DR   Q2YDF1, TRMB_BOVIN ;  Q89WA4, TRMB_BRAJA ;  C0ZHY5, TRMB_BREBN ;
DR   Q2YQS1, TRMB_BRUA2 ;  Q57AA4, TRMB_BRUAB ;  A8NFF0, TRMB_BRUMA ;
DR   Q8YEA9, TRMB_BRUME ;  Q8FXT6, TRMB_BRUSU ;  B8D9X3, TRMB_BUCA5 ;
DR   P57616, TRMB_BUCAI ;  Q8K927, TRMB_BUCAP ;  B8D875, TRMB_BUCAT ;
DR   Q89A46, TRMB_BUCBP ;  Q1BYF4, TRMB_BURCA ;  A0K594, TRMB_BURCH ;
DR   Q0BHL9, TRMB_BURCM ;  Q62HT7, TRMB_BURMA ;  Q3JPL2, TRMB_BURP1 ;
DR   Q63RN0, TRMB_BURPS ;  Q39IU7, TRMB_BURS3 ;  Q2SYE0, TRMB_BURTA ;
DR   A4JC58, TRMB_BURVG ;  Q13V14, TRMB_BURXL ;  A8WTA7, TRMB_CAEBR ;
DR   Q23126, TRMB_CAEEL ;  A0RQ93, TRMB_CAMFF ;  A8FMY4, TRMB_CAMJ8 ;
DR   A7H2A2, TRMB_CAMJD ;  Q9PN20, TRMB_CAMJE ;  A1W0R3, TRMB_CAMJJ ;
DR   Q5HTI5, TRMB_CAMJR ;  Q5A692, TRMB_CANAL ;  Q6FNR1, TRMB_CANGA ;
DR   B8GX04, TRMB_CAUCN ;  P58088, TRMB_CAUCR ;  B0T162, TRMB_CAUSK ;
DR   Q2GS86, TRMB_CHAGB ;  A9WHH4, TRMB_CHLAA ;  Q5L5A2, TRMB_CHLAB ;
DR   B8GAY2, TRMB_CHLAD ;  P59718, TRMB_CHLCV ;  Q255M7, TRMB_CHLFF ;
DR   Q9PL91, TRMB_CHLMU ;  A1BGS9, TRMB_CHLPD ;  Q9Z6S3, TRMB_CHLPN ;
DR   B9LBT1, TRMB_CHLSY ;  B3QY13, TRMB_CHLT3 ;  Q3KKL0, TRMB_CHLTA ;
DR   O84836, TRMB_CHLTR ;  Q1QSR9, TRMB_CHRSD ;  Q7NRJ5, TRMB_CHRVO ;
DR   Q97FU9, TRMB_CLOAB ;  A7FRB3, TRMB_CLOB1 ;  C3L0Q0, TRMB_CLOB6 ;
DR   A6LRN7, TRMB_CLOB8 ;  B2V2I8, TRMB_CLOBA ;  B2TM00, TRMB_CLOBB ;
DR   A5HZ44, TRMB_CLOBH ;  C1FSH8, TRMB_CLOBJ ;  B1IEK9, TRMB_CLOBK ;
DR   A7GAQ4, TRMB_CLOBL ;  B1KV69, TRMB_CLOBM ;  B8I005, TRMB_CLOCE ;
DR   Q187Q1, TRMB_CLOD6 ;  B9E4X8, TRMB_CLOK1 ;  A5N127, TRMB_CLOK5 ;
DR   A0Q2J7, TRMB_CLONN ;  Q0TU06, TRMB_CLOP1 ;  Q8XNB4, TRMB_CLOPE ;
DR   A9KLV5, TRMB_CLOPH ;  Q0SVU9, TRMB_CLOPS ;  Q897E6, TRMB_CLOTE ;
DR   A3DBL4, TRMB_CLOTH ;  Q47WM2, TRMB_COLP3 ;  B5Y822, TRMB_COPPD ;
DR   Q6NET4, TRMB_CORDI ;  Q8FM11, TRMB_COREF ;  A4QHQ6, TRMB_CORGB ;
DR   Q8NLS3, TRMB_CORGL ;  Q4JY06, TRMB_CORJK ;  B1VEE1, TRMB_CORU7 ;
DR   P0CS81, TRMB_CRYNB ;  P0CS80, TRMB_CRYNJ ;  B0WSB8, TRMB_CULQU ;
DR   Q0K7S5, TRMB_CUPNH ;  Q474P5, TRMB_CUPPJ ;  Q11UV2, TRMB_CYTH3 ;
DR   Q5XJ57, TRMB_DANRE ;  Q6BX78, TRMB_DEBHA ;  Q478Z3, TRMB_DECAR ;
DR   Q1IWK0, TRMB_DEIGD ;  Q9RTS6, TRMB_DEIRA ;  B8G1D7, TRMB_DESHD ;
DR   Q24W00, TRMB_DESHY ;  Q551M3, TRMB_DICDI ;  B3MYY4, TRMB_DROAN ;
DR   B3P8V8, TRMB_DROER ;  B4JLU7, TRMB_DROGR ;  O77263, TRMB_DROME ;
DR   B4L529, TRMB_DROMO ;  B4H4I3, TRMB_DROPE ;  Q29I16, TRMB_DROPS ;
DR   B4I9N7, TRMB_DROSE ;  B4R338, TRMB_DROSI ;  B4M703, TRMB_DROVI ;
DR   B4N278, TRMB_DROWI ;  B4Q1B6, TRMB_DROYA ;  A7ZR85, TRMB_ECO24 ;
DR   P0A8I6, TRMB_ECO57 ;  A8A4A3, TRMB_ECOHS ;  A1AFE6, TRMB_ECOK1 ;
DR   Q0TDP1, TRMB_ECOL5 ;  Q8FE22, TRMB_ECOL6 ;  B1IT47, TRMB_ECOLC ;
DR   P0A8I5, TRMB_ECOLI ;  Q1R766, TRMB_ECOUT ;  C5BCF2, TRMB_EDWI9 ;
DR   P59719, TRMB_ENTFA ;  A7MLY2, TRMB_ENTS8 ;  Q6D8J7, TRMB_ERWCT ;
DR   Q2N5V5, TRMB_ERYLH ;  B1YKF9, TRMB_EXIS2 ;  C4L4Q4, TRMB_EXISA ;
DR   B0TXQ5, TRMB_FRAP2 ;  A7NAY4, TRMB_FRATF ;  A0Q7Q5, TRMB_FRATN ;
DR   Q0BMU5, TRMB_FRATO ;  Q8R6G8, TRMB_FUSNN ;  Q5KW28, TRMB_GEOKA ;
DR   Q39R75, TRMB_GEOMG ;  Q74FT5, TRMB_GEOSL ;  C5D6C2, TRMB_GEOSW ;
DR   A4IRW9, TRMB_GEOTN ;  Q5H737, TRMB_GLOLA ;  Q0BPF6, TRMB_GRABC ;
DR   A0LXL4, TRMB_GRAFK ;  Q7VN18, TRMB_HAEDU ;  Q4QNK0, TRMB_HAEI8 ;
DR   A5UAE5, TRMB_HAEIE ;  A5UGF0, TRMB_HAEIG ;  P44648, TRMB_HAEIN ;
DR   Q0I516, TRMB_HAES1 ;  B0UWE3, TRMB_HAES2 ;  Q2S8L4, TRMB_HAHCH ;
DR   A1WZP9, TRMB_HALHL ;  Q17Y01, TRMB_HELAH ;  Q7VI24, TRMB_HELHP ;
DR   Q1CTC3, TRMB_HELPH ;  Q9ZL96, TRMB_HELPJ ;  O25443, TRMB_HELPY ;
DR   Q9UBP6, TRMB_HUMAN ;  Q0C600, TRMB_HYPNA ;  Q5QY61, TRMB_IDILO ;
DR   Q28UI8, TRMB_JANSC ;  A6TDW8, TRMB_KLEP7 ;  Q6CY47, TRMB_KLULA ;
DR   Q5FIS5, TRMB_LACAC ;  Q03QE7, TRMB_LACBA ;  Q037Y3, TRMB_LACC3 ;
DR   B3WF63, TRMB_LACCB ;  Q1G997, TRMB_LACDA ;  Q049E6, TRMB_LACDB ;
DR   B2GDC8, TRMB_LACF3 ;  Q041S2, TRMB_LACGA ;  A8YWH0, TRMB_LACH4 ;
DR   Q74I98, TRMB_LACJO ;  Q9CHI2, TRMB_LACLA ;  A2RM55, TRMB_LACLM ;
DR   Q030M2, TRMB_LACLS ;  Q88WZ9, TRMB_LACPL ;  A5VKZ3, TRMB_LACRD ;
DR   B2G8C8, TRMB_LACRJ ;  Q1WUP5, TRMB_LACS1 ;  Q38XZ3, TRMB_LACSS ;
DR   Q5X7R0, TRMB_LEGPA ;  A5IHB4, TRMB_LEGPC ;  Q5ZY91, TRMB_LEGPH ;
DR   Q5WZ61, TRMB_LEGPL ;  Q6AFR0, TRMB_LEIXX ;  Q04W54, TRMB_LEPBJ ;
DR   Q04XB2, TRMB_LEPBL ;  Q72W15, TRMB_LEPIC ;  Q8F9Q1, TRMB_LEPIN ;
DR   B1MZE7, TRMB_LEUCK ;  Q03WU9, TRMB_LEUMM ;  Q92B94, TRMB_LISIN ;
DR   Q71Z52, TRMB_LISMF ;  B8DHC7, TRMB_LISMH ;  Q8Y6R8, TRMB_LISMO ;
DR   A0AJ67, TRMB_LISW6 ;  A5E7T4, TRMB_LODEL ;  B1HXA1, TRMB_LYSSC ;
DR   B9E7G7, TRMB_MACCJ ;  Q2VYQ1, TRMB_MAGSA ;  A0L4N8, TRMB_MAGSM ;
DR   B6SHG7, TRMB_MAIZE ;  Q65VT5, TRMB_MANSM ;  A1TY08, TRMB_MARAV ;
DR   Q0AK73, TRMB_MARMM ;  Q6F1P8, TRMB_MESFL ;  Q11BD3, TRMB_MESSB ;
DR   Q608G0, TRMB_METCA ;  Q1H4T5, TRMB_METFK ;  A2SJR5, TRMB_METPP ;
DR   B0JUK5, TRMB_MICAN ;  Q9Z120, TRMB_MOUSE ;  A0QME9, TRMB_MYCA1 ;
DR   A5IZB9, TRMB_MYCAP ;  P67499, TRMB_MYCBO ;  A1KF28, TRMB_MYCBP ;
DR   C1AJN3, TRMB_MYCBT ;  Q2SRA2, TRMB_MYCCT ;  Q7NBG2, TRMB_MYCGA ;
DR   P47589, TRMB_MYCGE ;  A4T3S4, TRMB_MYCGI ;  Q600J2, TRMB_MYCH2 ;
DR   Q4A7Q7, TRMB_MYCH7 ;  Q4A9M3, TRMB_MYCHJ ;  Q9F411, TRMB_MYCHP ;
DR   B8ZTI4, TRMB_MYCLB ;  Q9CCZ9, TRMB_MYCLE ;  Q6KHE8, TRMB_MYCMO ;
DR   Q6MU75, TRMB_MYCMS ;  Q73TS5, TRMB_MYCPA ;  Q8EWB6, TRMB_MYCPE ;
DR   P75256, TRMB_MYCPN ;  Q98R44, TRMB_MYCPU ;  Q4A6T7, TRMB_MYCS5 ;
DR   A1U992, TRMB_MYCSK ;  Q1BFP0, TRMB_MYCSS ;  A5TYT3, TRMB_MYCTA ;
DR   P67498, TRMB_MYCTU ;  A0PMW8, TRMB_MYCUA ;  A1T1J8, TRMB_MYCVP ;
DR   Q1D096, TRMB_MYXXD ;  Q5F929, TRMB_NEIG1 ;  B4RMI6, TRMB_NEIG2 ;
DR   A9LZQ8, TRMB_NEIM0 ;  Q9JU19, TRMB_NEIMA ;  Q9JZ24, TRMB_NEIMB ;
DR   A1KUF5, TRMB_NEIMF ;  A1CWA9, TRMB_NEOFI ;  Q2GCL0, TRMB_NEOSM ;
DR   Q7RZC1, TRMB_NEUCR ;  Q0AJ68, TRMB_NITEC ;  P59720, TRMB_NITEU ;
DR   Q1QS68, TRMB_NITHX ;  Q2YCZ3, TRMB_NITMU ;  Q3JCB2, TRMB_NITOC ;
DR   Q3SWQ3, TRMB_NITWN ;  Q5YNA5, TRMB_NOCFA ;  A1SNN2, TRMB_NOCSJ ;
DR   Q8YVX4, TRMB_NOSS1 ;  Q2GBM0, TRMB_NOVAD ;  Q8EP25, TRMB_OCEIH ;
DR   A6WWW9, TRMB_OCHA4 ;  Q04EH7, TRMB_OENOB ;  A2YB34, TRMB_ORYSI ;
DR   Q67V78, TRMB_ORYSJ ;  A1B475, TRMB_PARDP ;  Q6MBP0, TRMB_PARUW ;
DR   Q9CLC2, TRMB_PASMU ;  Q03GC9, TRMB_PEDPA ;  Q3A6I7, TRMB_PELCD ;
DR   Q0TZT0, TRMB_PHANO ;  Q7N7H9, TRMB_PHOLL ;  Q6LML0, TRMB_PHOPR ;
DR   A5DC23, TRMB_PICGU ;  A3LS77, TRMB_PICST ;  B2AR91, TRMB_PODAN ;
DR   A1VRF7, TRMB_POLNA ;  Q129H3, TRMB_POLSJ ;  Q7MVS9, TRMB_PORGI ;
DR   Q6A6S9, TRMB_PROAC ;  A2C073, TRMB_PROM1 ;  A8G2P9, TRMB_PROM2 ;
DR   A2CCG0, TRMB_PROM3 ;  A2BUM1, TRMB_PROM5 ;  Q31CU2, TRMB_PROM9 ;
DR   Q7VDU8, TRMB_PROMA ;  Q7V4W7, TRMB_PROMM ;  Q7V350, TRMB_PROMP ;
DR   A2BP39, TRMB_PROMS ;  Q46HD3, TRMB_PROMT ;  Q48CM0, TRMB_PSE14 ;
DR   Q15ZS8, TRMB_PSEA6 ;  A6UYJ1, TRMB_PSEA7 ;  Q02U31, TRMB_PSEAB ;
DR   Q9I6B3, TRMB_PSEAE ;  Q1IGD2, TRMB_PSEE4 ;  Q4K4C6, TRMB_PSEF5 ;
DR   C3K3L6, TRMB_PSEFS ;  Q3ILJ1, TRMB_PSEHT ;  A4XZZ7, TRMB_PSEMY ;
DR   A5WAD6, TRMB_PSEP1 ;  Q3K588, TRMB_PSEPF ;  B0KN57, TRMB_PSEPG ;
DR   Q88CS7, TRMB_PSEPK ;  B1J2G9, TRMB_PSEPW ;  Q88AF5, TRMB_PSESM ;
DR   Q4ZM56, TRMB_PSEU2 ;  A4VRK4, TRMB_PSEU5 ;  Q4FQX9, TRMB_PSYA2 ;
DR   Q1Q963, TRMB_PSYCK ;  A1SRX3, TRMB_PSYIN ;  Q1LJU9, TRMB_RALME ;
DR   B2U7E2, TRMB_RALPJ ;  Q8Y1I7, TRMB_RALSO ;  Q2KD95, TRMB_RHIEC ;
DR   Q1MMC3, TRMB_RHIL3 ;  Q98BJ3, TRMB_RHILO ;  Q92SI3, TRMB_RHIME ;
DR   Q7UN36, TRMB_RHOBA ;  Q21X81, TRMB_RHOFD ;  Q2J2K3, TRMB_RHOP2 ;
DR   Q07V74, TRMB_RHOP5 ;  Q6NCM9, TRMB_RHOPA ;  Q21C37, TRMB_RHOPB ;
DR   Q13EL3, TRMB_RHOPS ;  Q2RMS4, TRMB_RHORT ;  Q3IW88, TRMB_RHOS4 ;
DR   Q0S679, TRMB_RHOSR ;  Q161H1, TRMB_ROSDO ;  Q1AUF5, TRMB_RUBXD ;
DR   A1AXP6, TRMB_RUTMC ;  Q21EN2, TRMB_SACD2 ;  A9MQR6, TRMB_SALAR ;
DR   Q57K06, TRMB_SALCH ;  Q5PMK3, TRMB_SALPA ;  Q8Z3U1, TRMB_SALTI ;
DR   Q8ZM40, TRMB_SALTY ;  Q96WV1, TRMB_SCHPO ;  A8GJ47, TRMB_SERP5 ;
DR   A1S8I6, TRMB_SHEAM ;  B8E918, TRMB_SHEB2 ;  A3D707, TRMB_SHEB5 ;
DR   A6WQU4, TRMB_SHEB8 ;  A9KXQ5, TRMB_SHEB9 ;  Q12KQ0, TRMB_SHEDO ;
DR   Q07Z53, TRMB_SHEFN ;  B0TJD3, TRMB_SHEHH ;  Q8EBX8, TRMB_SHEON ;
DR   A8H1J9, TRMB_SHEPA ;  A4Y8Y5, TRMB_SHEPC ;  B8CS82, TRMB_SHEPW ;
DR   A0KUE8, TRMB_SHESA ;  A8FSK8, TRMB_SHESH ;  Q0HL06, TRMB_SHESM ;
DR   Q0HXA4, TRMB_SHESR ;  A1RHL0, TRMB_SHESW ;  B1KIW4, TRMB_SHEWM ;
DR   Q31WM2, TRMB_SHIBS ;  Q32C29, TRMB_SHIDS ;  Q0T0S8, TRMB_SHIF8 ;
DR   P0A8I7, TRMB_SHIFL ;  Q3YXE7, TRMB_SHISS ;  Q5LLK8, TRMB_SILPO ;
DR   Q1GK88, TRMB_SILST ;  A6U5H7, TRMB_SINMW ;  Q2NRB6, TRMB_SODGM ;
DR   Q1GNC9, TRMB_SPHAL ;  A7X3I5, TRMB_STAA1 ;  A6U2L4, TRMB_STAA2 ;
DR   Q2FFZ0, TRMB_STAA3 ;  Q2FXI2, TRMB_STAA8 ;  A5ITS0, TRMB_STAA9 ;
DR   Q2YTI8, TRMB_STAAB ;  Q9KWZ4, TRMB_STAAC ;  A6QHT1, TRMB_STAAE ;
DR   P67500, TRMB_STAAM ;  P67501, TRMB_STAAN ;  Q6GFV3, TRMB_STAAR ;
DR   Q6G8H9, TRMB_STAAS ;  A8Z4H5, TRMB_STAAT ;  Q8NW26, TRMB_STAAW ;
DR   B9DN65, TRMB_STACT ;  Q5HNG2, TRMB_STAEQ ;  Q8CS43, TRMB_STAES ;
DR   Q4L792, TRMB_STAHJ ;  Q49YH9, TRMB_STAS1 ;  Q3K307, TRMB_STRA1 ;
DR   P67502, TRMB_STRA3 ;  P67503, TRMB_STRA5 ;  P59721, TRMB_STRAW ;
DR   Q9F305, TRMB_STRCO ;  C0M8F7, TRMB_STRE4 ;  B4U1E2, TRMB_STREM ;
DR   A8AVP7, TRMB_STRGC ;  B4STS7, TRMB_STRM5 ;  B2FSD1, TRMB_STRMK ;
DR   Q8DVQ4, TRMB_STRMU ;  P67504, TRMB_STRP1 ;  Q04LW5, TRMB_STRP2 ;
DR   P0DG18, TRMB_STRP3 ;  B5E261, TRMB_STRP4 ;  Q5XAG6, TRMB_STRP6 ;
DR   C1C5S3, TRMB_STRP7 ;  Q8NZU4, TRMB_STRP8 ;  Q1JAB6, TRMB_STRPB ;
DR   Q1JKG6, TRMB_STRPC ;  Q1JFF9, TRMB_STRPD ;  Q1J5A9, TRMB_STRPF ;
DR   A2RCZ6, TRMB_STRPG ;  B1IA75, TRMB_STRPI ;  B8ZM88, TRMB_STRPJ ;
DR   Q48RU3, TRMB_STRPM ;  P67506, TRMB_STRPN ;  P0DG19, TRMB_STRPQ ;
DR   B2IMD9, TRMB_STRPS ;  B5XHV8, TRMB_STRPZ ;  P67507, TRMB_STRR6 ;
DR   A4W3S2, TRMB_STRS2 ;  C0MDZ0, TRMB_STRS7 ;  A3CQ23, TRMB_STRSV ;
DR   A4VXH8, TRMB_STRSY ;  Q5LYG9, TRMB_STRT1 ;  Q5M332, TRMB_STRT2 ;
DR   Q03JA3, TRMB_STRTD ;  B9DVC2, TRMB_STRU0 ;  C1CCT3, TRMB_STRZJ ;
DR   C1CJ34, TRMB_STRZP ;  C1CQ43, TRMB_STRZT ;  Q30SG7, TRMB_SULDN ;
DR   P72546, TRMB_SYNE7 ;  Q2JRH1, TRMB_SYNJA ;  Q2JJQ0, TRMB_SYNJB ;
DR   Q5N2X5, TRMB_SYNP6 ;  A5GIJ2, TRMB_SYNPW ;  Q7U9H3, TRMB_SYNPX ;
DR   Q0IDB0, TRMB_SYNS3 ;  Q3AW35, TRMB_SYNS9 ;  Q3AMX6, TRMB_SYNSC ;
DR   P73161, TRMB_SYNY3 ;  Q8DHH6, TRMB_THEEB ;  Q9X027, TRMB_THEMA ;
DR   Q72I77, TRMB_THET2 ;  Q5SHW1, TRMB_THET8 ;  Q31JF8, TRMB_THICR ;
DR   Q3SH11, TRMB_THIDA ;  Q73NM2, TRMB_TREDE ;  O83477, TRMB_TREPA ;
DR   B2S360, TRMB_TREPS ;  Q117P8, TRMB_TRIEI ;  B1AIQ8, TRMB_UREP2 ;
DR   Q9PQM2, TRMB_UREPA ;  B5ZB79, TRMB_UREU1 ;  A7TT36, TRMB_VANPO ;
DR   A1WIH0, TRMB_VEREI ;  A5F9I8, TRMB_VIBC3 ;  Q9KUR2, TRMB_VIBCH ;
DR   C3LRX0, TRMB_VIBCM ;  B5F9R5, TRMB_VIBFM ;  A7MTN8, TRMB_VIBHB ;
DR   Q87LI7, TRMB_VIBPA ;  Q8DCC3, TRMB_VIBVU ;  Q7MHI6, TRMB_VIBVY ;
DR   Q73G71, TRMB_WOLPM ;  Q7MST9, TRMB_WOLSU ;  Q8PHF4, TRMB_XANAC ;
DR   Q3BQ14, TRMB_XANC5 ;  Q4UXY5, TRMB_XANC8 ;  Q8P631, TRMB_XANCP ;
DR   Q2P0J4, TRMB_XANOM ;  Q5GXE4, TRMB_XANOR ;  Q6NU94, TRMB_XENLA ;
DR   B2I9C6, TRMB_XYLF2 ;  Q9PF94, TRMB_XYLFA ;  B0U509, TRMB_XYLFM ;
DR   Q87AE9, TRMB_XYLFT ;  Q6CE12, TRMB_YARLI ;  B3LH81, TRMB_YEAS1 ;
DR   A6ZXD2, TRMB_YEAS7 ;  Q12009, TRMB_YEAST ;  A1JPV4, TRMB_YERE8 ;
DR   A7FEX6, TRMB_YERP3 ;  Q1CB91, TRMB_YERPA ;  Q8ZHE9, TRMB_YERPE ;
DR   Q1CEV4, TRMB_YERPN ;  A4TI61, TRMB_YERPP ;  Q666M5, TRMB_YERPS ;
DR   Q5NR81, TRMB_ZYMMO ;
//
ID   2.1.1.34
DE   tRNA guanosine-2'-O-methyltransferase.
AN   S-adenosyl-L-methionine:tRNA (guanosine-2'-O-)-methyltransferase.
AN   Transfer ribonucleate guanosine 2'-methyltransferase.
AN   tRNA (Gm18) 2'-O-methyltransferase.
AN   tRNA (Gm18) methyltransferase.
AN   tRNA (guanosine 2')-methyltransferase.
AN   tRNA (guanosine-2'-O-)-methyltransferase.
AN   tRNA guanosine 2'-methyltransferase.
CA   S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA
CA   containing 2'-O-methylguanosine.
CC   -!- Methylates the 2'-hydroxy group of a guanosine present in a GG
CC       sequence at position 18.
CC   -!- Yeast tRNA(Phe) is one of the best substrate tRNAs.
DR   Q07527, TRM3_YEAST ;  O67577, TRMH_AQUAE ;  P0AGJ3, TRMH_ECO57 ;
DR   P0AGJ2, TRMH_ECOLI ;  P0AGJ4, TRMH_SHIFL ;
//
ID   2.1.1.35
DE   tRNA (uracil-5-)-methyltransferase.
AN   M5U-methyltransferase.
AN   Ribothymidyl synthase.
AN   RUMT.
AN   Transfer RNA uracil 5-methyltransferase.
AN   Transfer RNA uracil methylase.
AN   tRNA uracil 5-methyltransferase.
AN   tRNA:m(5)U54-methyltransferase.
CA   S-adenosyl-L-methionine + tRNA containing uridine at position 54 =
CA   S-adenosyl-L-homocysteine + tRNA containing ribothymidine at position 54.
CC   -!- Up to 25% of the bases in mature tRNA are post-translationally
CC       modified or hypermodified.
CC   -!- One almost universal post-translational modification is the
CC       conversion of U(54) into ribothymidine in the T-Psi-C loop, and this
CC       modification is found in most species studied to date.
CC   -!- Unlike this enzyme, EC 2.1.1.74 uses 5,10-methylenetetrahydrofolate
CC       and FADH(2) to supply the atoms for methylation of U(54).
PR   PROSITE; PDOC00945;
DR   A4QP75, TRM2B_DANRE;  Q96GJ1, TRM2_HUMAN ;  Q8BQJ6, TRM2_MOUSE ;
DR   Q5RFM7, TRM2_PONAB ;  P33753, TRM2_YEAST ;  Q6FBS0, TRMA_ACIAD ;
DR   B7H3Q6, TRMA_ACIB3 ;  B7I4Y4, TRMA_ACIB5 ;  B2HYZ7, TRMA_ACIBC ;
DR   B0VR22, TRMA_ACIBS ;  A3M4W0, TRMA_ACIBT ;  B0VCX5, TRMA_ACIBY ;
DR   A3N3R7, TRMA_ACTP2 ;  B3GZC6, TRMA_ACTP7 ;  B0BU06, TRMA_ACTPJ ;
DR   A6VLF9, TRMA_ACTSZ ;  A0KQR3, TRMA_AERHH ;  A4SHG2, TRMA_AERS4 ;
DR   C6AQU6, TRMA_AGGAN ;  B6ENT4, TRMA_ALISL ;  B4RYR7, TRMA_ALTMD ;
DR   A8EWU8, TRMA_ARCB4 ;  Q5P8D0, TRMA_AROAE ;  A1K524, TRMA_AZOSB ;
DR   C1DLS8, TRMA_AZOVD ;  A7ZDV3, TRMA_CAMC1 ;  A7GY40, TRMA_CAMC5 ;
DR   A0RPL1, TRMA_CAMFF ;  A7I332, TRMA_CAMHC ;  A8FLP0, TRMA_CAMJ8 ;
DR   A7H422, TRMA_CAMJD ;  Q9PP92, TRMA_CAMJE ;  A1VZH5, TRMA_CAMJJ ;
DR   Q5HUW5, TRMA_CAMJR ;  B9KCK3, TRMA_CAMLR ;  B3PJ74, TRMA_CELJU ;
DR   Q1QXW4, TRMA_CHRSD ;  A8AKV5, TRMA_CITK8 ;  Q48A12, TRMA_COLP3 ;
DR   Q47F12, TRMA_DECAR ;  C6C5A0, TRMA_DICDC ;  A5EXH9, TRMA_DICNV ;
DR   C6CG41, TRMA_DICZE ;  A7ZUI5, TRMA_ECO24 ;  B7UNU5, TRMA_ECO27 ;
DR   B7MIA5, TRMA_ECO45 ;  B7LA67, TRMA_ECO55 ;  Q8X723, TRMA_ECO57 ;
DR   B5Z069, TRMA_ECO5E ;  B7NU35, TRMA_ECO7I ;  B7MR93, TRMA_ECO81 ;
DR   B7M721, TRMA_ECO8A ;  C5WBK5, TRMA_ECOBD ;  C6UJK3, TRMA_ECOBR ;
DR   C5A0R4, TRMA_ECOBW ;  B1XBX6, TRMA_ECODH ;  A8A773, TRMA_ECOHS ;
DR   A1AIE7, TRMA_ECOK1 ;  Q0TA91, TRMA_ECOL5 ;  Q8CXW3, TRMA_ECOL6 ;
DR   B1IVB3, TRMA_ECOLC ;  P23003, TRMA_ECOLI ;  B7NFR5, TRMA_ECOLU ;
DR   B6I5I3, TRMA_ECOSE ;  B1LNS5, TRMA_ECOSM ;  Q1R3U2, TRMA_ECOUT ;
DR   C5BC48, TRMA_EDWI9 ;  A4WG46, TRMA_ENT38 ;  A7ML95, TRMA_ENTS8 ;
DR   Q6CZB4, TRMA_ERWCT ;  B2VGA5, TRMA_ERWT9 ;  B7LUM8, TRMA_ESCF3 ;
DR   Q7U339, TRMA_HAEDU ;  Q4QM53, TRMA_HAEI8 ;  A5UDM6, TRMA_HAEIE ;
DR   P31812, TRMA_HAEIN ;  B8F7Z1, TRMA_HAEPS ;  Q0I1I7, TRMA_HAES1 ;
DR   B0UVN9, TRMA_HAES2 ;  Q7U326, TRMA_HELHP ;  Q5QVT1, TRMA_IDILO ;
DR   B5XZ11, TRMA_KLEP3 ;  A6TGE9, TRMA_KLEP7 ;  Q65PY6, TRMA_MANSM ;
DR   A6W3C7, TRMA_MARMS ;  B9LA97, TRMA_NAUPA ;  Q5F757, TRMA_NEIG1 ;
DR   B4RN45, TRMA_NEIG2 ;  P55134, TRMA_NEIGO ;  A9M1Q1, TRMA_NEIM0 ;
DR   Q9JT82, TRMA_NEIMA ;  Q9JYA0, TRMA_NEIMB ;  A1KV88, TRMA_NEIMF ;
DR   A6Q2V7, TRMA_NITSB ;  Q9CK32, TRMA_PASMU ;  C6DHQ1, TRMA_PECCP ;
DR   Q7MAX6, TRMA_PHOLL ;  Q6LLU2, TRMA_PHOPR ;  B4F1H4, TRMA_PROMH ;
DR   Q48DT0, TRMA_PSE14 ;  Q15NK9, TRMA_PSEA6 ;  A6VCH5, TRMA_PSEA7 ;
DR   B7V1D2, TRMA_PSEA8 ;  Q02FV3, TRMA_PSEAB ;  Q9HV78, TRMA_PSEAE ;
DR   Q1I4J8, TRMA_PSEE4 ;  Q4K5P2, TRMA_PSEF5 ;  Q9RHS9, TRMA_PSEFL ;
DR   C3K2F6, TRMA_PSEFS ;  Q3ILM2, TRMA_PSEHT ;  A4XQI3, TRMA_PSEMY ;
DR   A5W926, TRMA_PSEP1 ;  Q3K6G9, TRMA_PSEPF ;  B0KHR5, TRMA_PSEPG ;
DR   Q88E14, TRMA_PSEPK ;  B1J3Q4, TRMA_PSEPW ;  Q87WA0, TRMA_PSESM ;
DR   Q4ZNF5, TRMA_PSEU2 ;  A4VI15, TRMA_PSEU5 ;  A1SSL6, TRMA_PSYIN ;
DR   Q21KA1, TRMA_SACD2 ;  B5F0V3, TRMA_SALA4 ;  A9MHG7, TRMA_SALAR ;
DR   Q57H88, TRMA_SALCH ;  B5FPX9, TRMA_SALDC ;  B5QXR0, TRMA_SALEP ;
DR   B5REZ3, TRMA_SALG2 ;  B4TCR0, TRMA_SALHS ;  B4T0X5, TRMA_SALNS ;
DR   Q5PK68, TRMA_SALPA ;  A9N0H5, TRMA_SALPB ;  C0Q481, TRMA_SALPC ;
DR   B5BJN9, TRMA_SALPK ;  B4TQI0, TRMA_SALSV ;  Q8Z313, TRMA_SALTI ;
DR   P22038, TRMA_SALTY ;  A8GL74, TRMA_SERP5 ;  A1S1Z8, TRMA_SHEAM ;
DR   B8EBM5, TRMA_SHEB2 ;  A3DA80, TRMA_SHEB5 ;  A6WHQ8, TRMA_SHEB8 ;
DR   A9KW82, TRMA_SHEB9 ;  Q12SP8, TRMA_SHEDO ;  Q089S7, TRMA_SHEFN ;
DR   B0TMV6, TRMA_SHEHH ;  A3Q962, TRMA_SHELP ;  Q8CX51, TRMA_SHEON ;
DR   A8GYV6, TRMA_SHEPA ;  A4YB86, TRMA_SHEPC ;  B8CH56, TRMA_SHEPW ;
DR   A0KRK4, TRMA_SHESA ;  A8G1G7, TRMA_SHESH ;  Q0HNV8, TRMA_SHESM ;
DR   Q0I0C6, TRMA_SHESR ;  A1RP91, TRMA_SHESW ;  B1KN03, TRMA_SHEWM ;
DR   B2TWG0, TRMA_SHIB3 ;  Q31U23, TRMA_SHIBS ;  Q32AE5, TRMA_SHIDS ;
DR   Q0SY26, TRMA_SHIF8 ;  Q820Z9, TRMA_SHIFL ;  Q3YV11, TRMA_SHISS ;
DR   Q2NQZ6, TRMA_SODGM ;  Q30RT5, TRMA_SULDN ;  A6QBC0, TRMA_SULNB ;
DR   C5BTY4, TRMA_TERTT ;  Q31JA4, TRMA_THICR ;  C4L9A7, TRMA_TOLAT ;
DR   A5F4M4, TRMA_VIBC3 ;  Q9KVJ0, TRMA_VIBCH ;  C3LPZ5, TRMA_VIBCM ;
DR   Q5E215, TRMA_VIBF1 ;  B5FCA6, TRMA_VIBFM ;  A7MXY6, TRMA_VIBHB ;
DR   Q87KN8, TRMA_VIBPA ;  B7VM88, TRMA_VIBSL ;  Q8DD43, TRMA_VIBVU ;
DR   Q7MQ79, TRMA_VIBVY ;  Q7M7T6, TRMA_WOLSU ;  A1JI40, TRMA_YERE8 ;
DR   A7FD13, TRMA_YERP3 ;  Q1CBU2, TRMA_YERPA ;  B2JZF7, TRMA_YERPB ;
DR   Q8ZAA0, TRMA_YERPE ;  A9R6N8, TRMA_YERPG ;  Q1CNP1, TRMA_YERPN ;
DR   A4TRG1, TRMA_YERPP ;  Q66G58, TRMA_YERPS ;  B1JQ46, TRMA_YERPY ;
DR   Q09833, YAD7_SCHPO ;
//
ID   2.1.1.36
DE   tRNA (adenine-N(1)-)-methyltransferase.
CA   S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA
CA   containing N(1)-methyladenine.
CC   -!- The enzymes from different sources are specific for different adenine
CC       residues in tRNA.
DR   Q9BVS5, TR61B_HUMAN;  Q5JD38, TRM10_PYRKO;  Q4J894, TRM10_SULAC;
DR   Q755M8, TRM61_ASHGO;  Q4WUT7, TRM61_ASPFU;  Q2U3W4, TRM61_ASPOR;
DR   A6H791, TRM61_BOVIN;  Q5A416, TRM61_CANAL;  Q6FL77, TRM61_CANGA;
DR   P0CS09, TRM61_CRYNB;  P0CS08, TRM61_CRYNJ;  Q6BX32, TRM61_DEBHA;
DR   Q86JJ0, TRM61_DICDI;  Q96FX7, TRM61_HUMAN;  Q6CN53, TRM61_KLULA;
DR   Q80XC2, TRM61_MOUSE;  Q6AY46, TRM61_RAT  ;  O14307, TRM61_SCHPO;
DR   Q6C0P9, TRM61_YARLI;  P46959, TRM61_YEAST;  Q57598, TRMI_METJA ;
DR   O33253, TRMI_MYCTU ;  Q9V1J7, TRMI_PYRAB ;  Q8GBB2, TRMI_THET2 ;
DR   Q5SKN4, TRMI_THET8 ;  P54471, TRMK_BACSU ;  P47490, Y248_MYCGE ;
DR   P75427, Y351_MYCPN ;
//
ID   2.1.1.37
DE   DNA (cytosine-5-)-methyltransferase.
AN   Cytosine 5-methyltransferase.
AN   Cytosine DNA methylase.
AN   Cytosine DNA methyltransferase.
AN   Cytosine-specific DNA methyltransferase.
AN   Deoxyribonucleate methylase.
AN   Deoxyribonucleate methyltransferase.
AN   Deoxyribonucleic (cytosine-5-)-methyltransferase.
AN   Deoxyribonucleic acid (cytosine-5-)-methyltransferase.
AN   Deoxyribonucleic acid methylase.
AN   Deoxyribonucleic acid methyltransferase.
AN   Deoxyribonucleic acid modification methylase.
AN   Deoxyribonucleic methylase.
AN   DNA 5-cytosine methylase.
AN   DNA cytosine C(5) methylase.
AN   DNA cytosine methylase.
AN   DNA methylase.
AN   DNA methyltransferase.
AN   DNA transmethylase.
AN   DNA-cytosine 5-methylase.
AN   DNA-cytosine methyltransferase.
AN   Methylphosphotriester-DNA methyltransferase.
AN   Modification methylase.
AN   Restriction-modification system.
AN   Site-specific DNA-methyltransferase (cytosine-specific).
AN   Type II DNA methylase.
CA   S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine +
CA   DNA containing 5-methylcytosine.
CC   -!- See the REBASE database for a complete list of these enzymes:
CC       http://rebase.neb.com/rebase/
CC   -!- Formerly EC 2.1.1.73.
PR   PROSITE; PDOC00089;
DR   O49139, CMT1_ARATH ;  Q54JH6, CMT1_DICDI ;  Q9AXT8, CMT1_MAIZE ;
DR   Q94F87, CMT2_ARATH ;  Q9ARI6, CMT2_MAIZE ;  Q94F88, CMT3_ARATH ;
DR   Q8LPU5, CMT3_MAIZE ;  P0AEE0, DCM_ECO57  ;  P0AED9, DCM_ECOLI  ;
DR   Q7Y1I7, DNM1A_ORYSJ;  B1Q3J6, DNM1B_ORYSJ;  Q4W5Z4, DNM3A_CHICK;
DR   Q9Y6K1, DNM3A_HUMAN;  O88508, DNM3A_MOUSE;  Q1LZ53, DNM3A_RAT  ;
DR   Q9UBC3, DNM3B_HUMAN;  O88509, DNM3B_MOUSE;  P34881, DNMT1_ARATH;
DR   Q24K09, DNMT1_BOVIN;  Q92072, DNMT1_CHICK;  P26358, DNMT1_HUMAN;
DR   P13864, DNMT1_MOUSE;  Q27746, DNMT1_PARLI;  Q9Z330, DNMT1_RAT  ;
DR   Q67472, DNMT_FRG3G ;  Q9LXE5, DRM1_ARATH ;  Q9M548, DRM2_ARATH ;
DR   Q8EL95, MT36_OCEIH ;  Q57983, MT51_METJA ;  Q58600, MT52_METJA ;
DR   O52702, MTA1_ACEPA ;  P31974, MTA1_CELCE ;  P94147, MTA1_RUEGE ;
DR   P34882, MTAA_SYNP2 ;  P34883, MTAB_SYNP2 ;  P34905, MTB1_BREBE ;
DR   P10283, MTB1_BREEP ;  P25262, MTB1_HERAU ;  P13906, MTB1_LYSSH ;
DR   Q59603, MTB1_NEIGO ;  Q59605, MTB5_NEIGO ;  P43420, MTB6_BACSF ;
DR   P19888, MTBA_BACAR ;  P09389, MTBB_BPSPB ;  P17044, MTBF_BACSU ;
DR   P68585, MTBP_BACSU ;  P68586, MTBP_BPPHT ;  P06530, MTBR_BACSU ;
DR   P09915, MTBR_BPRH1 ;  P00476, MTBS_BPSPR ;  P25263, MTC1_HERAU ;
DR   P36216, MTC1_PBCVI ;  P25264, MTC2_HERAU ;  P05302, MTD1_DESNO ;
DR   P24600, MTD1_HERAU ;  Q9RLM4, MTD1_NEIMC ;  P25265, MTD2_HERAU ;
DR   P50185, MTD5_DACSA ;  P25266, MTE1_HERAU ;  P05101, MTE2_ECOLX ;
DR   P50196, MTE8_ECOLX ;  P34906, MTF1_FUSNU ;  Q59606, MTF7_NEIGO ;
DR   P25282, MTG1_HAEGA ;  P25267, MTG1_HERAU ;  P25283, MTG2_HAEGA ;
DR   P05102, MTH1_HAEPH ;  O30868, MTH2_HAEAE ;  P15446, MTH2_HAEPA ;
DR   P20589, MTH3_HAEAE ;  P45000, MTH5_HAEIN ;  P50192, MTHA_HAEPH ;
DR   P29567, MTHT_METTF ;  P11408, MTM1_MORSP ;  P31033, MTM4_NEIGO ;
DR   P50188, MTN1_NOCAE ;  P50182, MTN4_NEILA ;  P24581, MTNX_NEILA ;
DR   O33481, MTP1_PSYTA ;  P08455, MTP2_NEIGO ;  P09795, MTS1_SALIN ;
DR   O31073, MTS1_STRAH ;  P34879, MTS2_SHISO ;  P16668, MTS3_STAAU ;
DR   P23737, MTS9_STAAU ;  P34877, MTSA_LACLC ;  P34878, MTSB_LACLC ;
DR   P15840, MTSI_SPISQ ;  P52311, MTX2_XANOR ;  O34939, YDIO_BACSU ;
DR   O34680, YDIP_BACSU ;
//
ID   2.1.1.38
DE   O-demethylpuromycin O-methyltransferase.
CA   S-adenosyl-L-methionine + O-demethylpuromycin = S-adenosyl-L-homocysteine
CA   + puromycin.
CC   -!- Puromycin is the antibiotic derived from N(6)-dimethyladenosine by
CC       replacing the 3'-hydroxy group with an amino group and acylating this
CC       with 4-O-methyltyrosine.
DR   P42712, DMPM_STRAD ;
//
ID   2.1.1.39
DE   Inositol 3-methyltransferase.
AN   Inositol L-1-methyltransferase.
AN   Myo-inositol 1-methyltransferase.
AN   Myo-inositol 1-O-methyltransferase.
AN   S-adenosyl-L-methionine:myo-inositol 1-O-methyltransferase.
CA   S-adenosyl-L-methionine + myo-inositol = S-adenosyl-L-homocysteine +
CA   1D-3-O-methyl-myo-inositol.
//
ID   2.1.1.40
DE   Inositol 1-methyltransferase.
AN   Inositol 3-O-methyltransferase.
AN   Inositol D-1-methyltransferase.
AN   Myo-inositol 3-O-methyltransferase.
AN   S-adenosyl-L-methionine:myo-inositol 3-O-methyltransferase.
AN   S-adenosylmethionine:myo-inositol 3-methyltransferase.
CA   S-adenosyl-L-methionine + myo-inositol = S-adenosyl-L-homocysteine +
CA   1D-1-O-methyl-myo-inositol.
//
ID   2.1.1.41
DE   Sterol 24-C-methyltransferase.
AN   24-sterol C-methyltransferase.
AN   Delta(24)-methyltransferase.
AN   Delta(24)-sterol methyltransferase.
AN   Phytosterol methyltransferase.
AN   S-adenosyl-4-methionine:sterol Delta(24)-methyltransferase.
AN   S-adenosyl-L-methionine:Delta(24(23))-sterol methyltransferase.
AN   SMT1.
AN   Zymosterol-24-methyltransferase.
CA   S-adenosyl-L-methionine + 5-alpha-cholesta-8,24-dien-3-beta-ol =
CA   S-adenosyl-L-homocysteine + 24-methylene-5-alpha-cholest-8-en-3-beta-ol.
CF   Glutathione.
CC   -!- Acts on a range of sterols with a 24(25)-double bond in the side
CC       chain.
CC   -!- While zymosterol is the preferred substrate it also acts on
CC       desmosterol, 5-alpha-cholesta-7,24-dien-3-beta-ol, 5-alpha-cholesta-
CC       5,7,24-trien-3-beta-ol, 4-alpha-methylzymosterol and others.
CC   -!- S-adenosyl-L-methionine attacks the Si face of the 24(25) double bond
CC       and the C-24 hydrogen is transferred to C-25 on the Re face of the
CC       double bond.
DR   Q759S7, ERG6_ASHGO ;  O74198, ERG6_CANAL ;  Q6FRZ7, ERG6_CANGA ;
DR   Q875K1, ERG6_CLAL4 ;  Q6BRB7, ERG6_DEBHA ;  Q6CYB3, ERG6_KLULA ;
DR   Q5EN22, ERG6_MAGO7 ;  Q9P3R1, ERG6_NEUCR ;  Q96WX4, ERG6_PNECA ;
DR   O14321, ERG6_SCHPO ;  Q6C2D9, ERG6_YARLI ;  P25087, ERG6_YEAST ;
DR   Q9LM02, SMT1_ARATH ;  Q54I98, SMT1_DICDI ;  Q6ZIX2, SMT1_ORYSJ ;
//
ID   2.1.1.42
DE   Luteolin O-methyltransferase.
AN   o-dihydric phenol methyltransferase.
CA   S-adenosyl-L-methionine + 5,7,3',4'-tetrahydroxyflavone = S-adenosyl-L-
CA   homocysteine + 5,7,4'-trihydroxy-3'-methoxyflavone.
CC   -!- Also acts on luteolin 7-O-beta-D-glucoside.
//
ID   2.1.1.43
DE   Histone-lysine N-methyltransferase.
AN   Protein methylase 3.
AN   Protein methylase III.
AN   Protein methyltransferase II.
AN   Protein-lysine N-methyltransferase.
CA   S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine
CA   + N(6)-methyl-L-lysine-[histone].
DR   Q9NR48, ASH1L_HUMAN;  Q99MY8, ASH1L_MOUSE;  Q9VW15, ASH1_DROME ;
DR   Q84WW6, ASHH1_ARATH;  Q2LAE1, ASHH2_ARATH;  Q945S8, ASHH3_ARATH;
DR   Q9M1X9, ASHH4_ARATH;  Q7XJS0, ASHR1_ARATH;  Q9ZUM9, ASHR2_ARATH;
DR   Q949T8, ASHR3_ARATH;  Q9C5X4, ATX1_ARATH ;  P0CB22, ATX2_ARATH ;
DR   Q9M364, ATX3_ARATH ;  Q9SUE7, ATX4_ARATH ;  Q8GZ42, ATX5_ARATH ;
DR   Q5PP37, ATXR2_ARATH;  O23372, ATXR3_ARATH;  Q9FG08, ATXR4_ARATH;
DR   Q8VZJ1, ATXR5_ARATH;  Q9FNE9, ATXR6_ARATH;  Q9VYD1, C1716_DROME;
DR   P93831, CLF_ARATH  ;  O60016, CLR4_SCHPO ;  Q8X225, DIM5_NEUCR ;
DR   Q8INR6, DOT1L_DROME;  Q8TEK3, DOT1L_HUMAN;  Q756E1, DOT1_ASHGO ;
DR   Q4WVH4, DOT1_ASPFU ;  Q2U696, DOT1_ASPOR ;  Q5A309, DOT1_CANAL ;
DR   Q6FNM5, DOT1_CANGA ;  Q2H9L1, DOT1_CHAGB ;  Q1DKD8, DOT1_COCIM ;
DR   P0CN15, DOT1_CRYNB ;  P0CN14, DOT1_CRYNJ ;  Q6BTC8, DOT1_DEBHA ;
DR   Q5BH89, DOT1_EMENI ;  Q4IJP1, DOT1_GIBZE ;  Q6CWV1, DOT1_KLULA ;
DR   Q7SB74, DOT1_NEUCR ;  Q4P2W8, DOT1_USTMA ;  Q6C4Y5, DOT1_YARLI ;
DR   Q04089, DOT1_YEAST ;  Q9H9B1, EHMT1_HUMAN;  Q5DW34, EHMT1_MOUSE;
DR   Q96KQ7, EHMT2_HUMAN;  Q9Z148, EHMT2_MOUSE;  Q8S4P6, EZ1_MAIZE  ;
DR   Q8S4P5, EZ2_MAIZE  ;  Q8S4P4, EZ3_MAIZE  ;  Q9ZSM8, EZA1_ARATH ;
DR   A7E2Z2, EZH1_BOVIN ;  Q92800, EZH1_HUMAN ;  P70351, EZH1_MOUSE ;
DR   Q5RDS6, EZH1_PONAB ;  Q98SM3, EZH2A_XENLA;  Q4V863, EZH2B_XENLA;
DR   Q08BS4, EZH2_DANRE ;  Q15910, EZH2_HUMAN ;  Q4R381, EZH2_MACFA ;
DR   Q61188, EZH2_MOUSE ;  Q28D84, EZH2_XENTR ;  P42124, EZ_DROME   ;
DR   C6KTD2, HKNMT_PLAF7;  O44757, LIN59_CAEEL;  O65312, MEDEA_ARATH;
DR   O17514, MES2_CAEEL ;  Q9NH52, MES4_CAEEL ;  Q8MT36, MES4_DROME ;
DR   P34544, MET2_CAEEL ;  Q03164, MLL1_HUMAN ;  P55200, MLL1_MOUSE ;
DR   O14686, MLL2_HUMAN ;  Q6PDK2, MLL2_MOUSE ;  Q8NEZ4, MLL3_HUMAN ;
DR   Q8BRH4, MLL3_MOUSE ;  Q9UMN6, MLL4_HUMAN ;  O08550, MLL4_MOUSE ;
DR   Q8IZD2, MLL5_HUMAN ;  Q3UG20, MLL5_MOUSE ;  Q96L73, NSD1_HUMAN ;
DR   O88491, NSD1_MOUSE ;  O96028, NSD2_HUMAN ;  Q8BVE8, NSD2_MOUSE ;
DR   Q9BZ95, NSD3_HUMAN ;  Q6P2L6, NSD3_MOUSE ;  Q13029, PRDM2_HUMAN;
DR   Q63755, PRDM2_RAT  ;  A6QPM3, PRDM6_BOVIN;  Q9NQX0, PRDM6_HUMAN;
DR   Q3UZD5, PRDM6_MOUSE;  Q9NQW5, PRDM7_HUMAN;  Q6P2A1, PRDM9_DANRE;
DR   Q9NQV7, PRDM9_HUMAN;  Q96EQ9, PRDM9_MOUSE;  P0C6Y7, PRDM9_RAT  ;
DR   Q6GP17, S421A_XENLA;  Q5RJX8, S421B_XENLA;  Q1LY77, SE1BA_DANRE;
DR   O15047, SET1A_HUMAN;  Q5F3P8, SET1B_CHICK;  Q9UPS6, SET1B_HUMAN;
DR   Q8CFT2, SET1B_MOUSE;  Q66J90, SET1B_XENLA;  Q08D57, SET1B_XENTR;
DR   Q75D88, SET1_ASHGO ;  Q4WNH8, SET1_ASPFU ;  Q2UMH3, SET1_ASPOR ;
DR   Q22795, SET1_CAEEL ;  Q5ABG1, SET1_CANAL ;  Q6FKB1, SET1_CANGA ;
DR   Q2GWF3, SET1_CHAGB ;  Q1DR06, SET1_COCIM ;  P0CO27, SET1_CRYNB ;
DR   P0CO26, SET1_CRYNJ ;  Q6BKL7, SET1_DEBHA ;  Q54HS3, SET1_DICDI ;
DR   Q5B0Y5, SET1_EMENI ;  Q4I5R3, SET1_GIBZE ;  Q6CIT4, SET1_KLULA ;
DR   Q8X0S9, SET1_NEUCR ;  Q9Y7R4, SET1_SCHPO ;  Q4PB36, SET1_USTMA ;
DR   Q6CEK8, SET1_YARLI ;  P38827, SET1_YEAST ;  A8XI75, SET23_CAEBR;
DR   Q95Y12, SET23_CAEEL;  Q757Y8, SET2_ASHGO ;  Q4WTT2, SET2_ASPFU ;
DR   Q2UTN6, SET2_ASPOR ;  Q18221, SET2_CAEEL ;  Q59XV0, SET2_CANAL ;
DR   Q6FX50, SET2_CANGA ;  Q2H988, SET2_CHAGB ;  Q1DU03, SET2_COCIM ;
DR   P0CO29, SET2_CRYNB ;  P0CO28, SET2_CRYNJ ;  Q6BM04, SET2_DEBHA ;
DR   Q5ASA5, SET2_EMENI ;  Q4IB50, SET2_GIBZE ;  Q6CXP5, SET2_KLULA ;
DR   Q7RZU4, SET2_NEUCR ;  O14026, SET2_SCHPO ;  Q4PBL3, SET2_USTMA ;
DR   Q6C5G5, SET2_YARLI ;  P46995, SET2_YEAST ;  O74467, SET5_SCHPO ;
DR   Q9Y7Q6, SET7_SCHPO ;  Q071E0, SET8A_DANRE;  Q08AY6, SET8A_XENLA;
DR   Q498E6, SET8B_XENLA;  Q4X1W8, SET9_ASPFU ;  Q2TZH4, SET9_ASPOR ;
DR   Q0C9E6, SET9_ASPTN ;  Q2H8D5, SET9_CHAGB ;  Q1E9C0, SET9_COCIM ;
DR   Q5AZY3, SET9_EMENI ;  Q4I8C9, SET9_GIBZE ;  Q7SBJ9, SET9_NEUCR ;
DR   Q0U3A4, SET9_PHANO ;  Q9USK2, SET9_SCHPO ;  Q6C519, SET9_YARLI ;
DR   Q32KD2, SETB1_DROME;  Q28Z18, SETB1_DROPS;  Q15047, SETB1_HUMAN;
DR   O88974, SETB1_MOUSE;  Q6INA9, SETB1_XENLA;  Q06ZW3, SETB2_DANRE;
DR   Q96T68, SETB2_HUMAN;  Q8C267, SETB2_MOUSE;  Q6YI93, SETB2_XENLA;
DR   A4IGY9, SETB2_XENTR;  Q9BYW2, SETD2_HUMAN;  B0VX69, SETD3_CALJA;
DR   B1MTJ4, SETD3_CALMO;  E2RBS6, SETD3_CANFA;  Q5ZML9, SETD3_CHICK;
DR   Q7SXS7, SETD3_DANRE;  C1FXW2, SETD3_DASNO;  Q86TU7, SETD3_HUMAN;
DR   Q91WC0, SETD3_MOUSE;  B5FW36, SETD3_OTOGA;  A9X1D0, SETD3_PAPAN;
DR   B2KI88, SETD3_RHIFE;  B7ZUF3, SETD3_XENTR;  Q6DHG0, SETD7_DANRE;
DR   Q7Z0G7, SETD7_HALRO;  Q8WTS6, SETD7_HUMAN;  Q8VHL1, SETD7_MOUSE;
DR   Q4QQN5, SETD7_XENTR;  Q2YDJ8, SETD8_BOVIN;  Q9VFK6, SETD8_DROME;
DR   Q297V5, SETD8_DROPS;  Q9NQR1, SETD8_HUMAN;  Q2YDW7, SETD8_MOUSE;
DR   Q0V9E9, SETD8_XENTR;  Q0VD24, SETMR_BOVIN;  Q53H47, SETMR_HUMAN;
DR   Q80UJ9, SETMR_MOUSE;  Q5I0M0, SETMR_RAT  ;  Q5BJI7, SMY2A_DANRE;
DR   Q7ZXV5, SMY2A_XENLA;  Q5RGL7, SMY2B_DANRE;  Q6GN68, SMY2B_XENLA;
DR   Q0P585, SMYD2_BOVIN;  E1C5V0, SMYD2_CHICK;  Q9NRG4, SMYD2_HUMAN;
DR   Q8R5A0, SMYD2_MOUSE;  C3RZA1, SMYD2_PIG  ;  Q7M6Z3, SMYD2_RAT  ;
DR   Q9H7B4, SMYD3_HUMAN;  Q9CWR2, SMYD3_MOUSE;  Q1L8U8, STB1A_DANRE;
DR   Q08BR4, STB1B_DANRE;  P45975, SUV39_DROME;  Q294B9, SUV39_DROPS;
DR   A8WTV9, SUV42_CAEBR;  Q09265, SUV42_CAEEL;  Q9W5E0, SUV42_DROME;
DR   Q2NL30, SUV91_BOVIN;  O43463, SUV91_HUMAN;  O54864, SUV91_MOUSE;
DR   Q5RB81, SUV91_PONAB;  Q6NRE8, SUV91_XENLA;  Q32PH7, SUV92_BOVIN;
DR   Q5F3W5, SUV92_CHICK;  Q9H5I1, SUV92_HUMAN;  Q4R3E0, SUV92_MACFA;
DR   Q9EQQ0, SUV92_MOUSE;  Q28CQ7, SUV92_XENTR;  Q9FF80, SUVH1_ARATH;
DR   Q93YF5, SUVH1_TOBAC;  O22781, SUVH2_ARATH;  Q9C5P4, SUVH3_ARATH;
DR   Q5QD03, SUVH3_CHLRE;  Q8GZB6, SUVH4_ARATH;  O82175, SUVH5_ARATH;
DR   Q8VZ17, SUVH6_ARATH;  Q9C5P1, SUVH7_ARATH;  Q9C5P0, SUVH8_ARATH;
DR   Q9T0G7, SUVH9_ARATH;  Q3EC60, SUVHA_ARATH;  Q946J2, SUVR1_ARATH;
DR   Q9FNC7, SUVR2_ARATH;  Q9SRV2, SUVR3_ARATH;  Q8W595, SUVR4_ARATH;
DR   O64827, SUVR5_ARATH;  Q29RP8, SV421_BOVIN;  Q5U3H2, SV421_DANRE;
DR   Q4FZB7, SV421_HUMAN;  Q3U8K7, SV421_MOUSE;  P0C2N5, SV421_RAT  ;
DR   Q86Y97, SV422_HUMAN;  Q6Q783, SV422_MOUSE;  P0C2N6, SV422_RAT  ;
DR   A0JMZ4, SV422_XENLA;  Q6DGD3, SV91A_DANRE;  Q8IRW8, TRR_DROME  ;
DR   P20659, TRX_DROME  ;  Q24742, TRX_DROVI  ;
//
ID   2.1.1.44
DE   Dimethylhistidine N-methyltransferase.
CA   S-adenosyl-L-methionine + N(alpha),N(alpha)-dimethyl-L-histidine =
CA   S-adenosyl-L-homocysteine + N(alpha),N(alpha),N(alpha)-trimethyl-L-
CA   histidine.
CC   -!- Methylhistidine and histidine can also act as methyl acceptors, with
CC       trimethylhistidine being formed in both cases.
//
ID   2.1.1.45
DE   Thymidylate synthase.
CA   5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP.
PR   PROSITE; PDOC00086;
DR   Q05762, DRTS1_ARATH;  Q05763, DRTS2_ARATH;  Q23695, DRTS_CRIFA ;
DR   P45350, DRTS_DAUCA ;  P16126, DRTS_LEIAM ;  P07382, DRTS_LEIMA ;
DR   O81395, DRTS_MAIZE ;  Q5UQG3, DRTS_MIMIV ;  Q2QRX6, DRTS_ORYSJ ;
DR   Q27828, DRTS_PARTE ;  Q27713, DRTS_PLABA ;  P20712, DRTS_PLACH ;
DR   P13922, DRTS_PLAFK ;  O02604, DRTS_PLAVI ;  P46103, DRTS_PLAVN ;
DR   P51820, DRTS_SOYBN ;  Q07422, DRTS_TOXGO ;  Q27783, DRTS_TRYBB ;
DR   Q27793, DRTS_TRYCR ;  O62584, TYS1_ENCCU ;  Q8SRG2, TYS3_ENCCU ;
DR   O30397, TYSY1_BACAM;  E0TVT6, TYSY1_BACPZ;  P0CI79, TYSY1_BACSU;
DR   P54081, TYSY2_BACAM;  E0U0H8, TYSY2_BACPZ;  P11044, TYSY2_BACSU;
DR   A9NG27, TYSY_ACHLI ;  A1TM53, TYSY_ACIAC ;  Q6FER7, TYSY_ACIAD ;
DR   B7H0P4, TYSY_ACIB3 ;  B7I4U0, TYSY_ACIB5 ;  A1W5A4, TYSY_ACISJ ;
DR   A6VMA0, TYSY_ACTSZ ;  A0KG32, TYSY_AERHH ;  A4SIW7, TYSY_AERS4 ;
DR   Q9P4T7, TYSY_AGABI ;  B9JH03, TYSY_AGRRK ;  Q8UDS3, TYSY_AGRT5 ;
DR   B9JXQ5, TYSY_AGRVS ;  Q0VM06, TYSY_ALCBS ;  Q0ABR1, TYSY_ALHEH ;
DR   B7GI39, TYSY_ANOFW ;  Q5P233, TYSY_AROAE ;  A1R8Y7, TYSY_ARTAT ;
DR   A0JZC7, TYSY_ARTS2 ;  O96650, TYSY_ASCSU ;  Q2NJ46, TYSY_AYWBP ;
DR   A1KAF7, TYSY_AZOSB ;  C1DK16, TYSY_AZOVD ;  A7Z5T3, TYSY_BACA2 ;
DR   A0RDL9, TYSY_BACAH ;  Q81R23, TYSY_BACAN ;  O30394, TYSY_BACAT ;
DR   Q738X7, TYSY_BACC1 ;  A7GP90, TYSY_BACCN ;  Q81E05, TYSY_BACCR ;
DR   Q63BV5, TYSY_BACCZ ;  Q5L9L6, TYSY_BACFN ;  Q64PV5, TYSY_BACFR ;
DR   Q9K7B5, TYSY_BACHD ;  Q6HJC7, TYSY_BACHK ;  Q65J44, TYSY_BACLD ;
DR   Q59212, TYSY_BACLI ;  Q9ANR7, TYSY_BACMO ;  Q5D189, TYSY_BACNA ;
DR   A8FEB9, TYSY_BACP2 ;  Q5WDS1, TYSY_BACSK ;  Q8A639, TYSY_BACTN ;
DR   A6L1Q8, TYSY_BACV8 ;  A1UTA5, TYSY_BARBK ;  Q6G2S8, TYSY_BARHE ;
DR   Q6FZ91, TYSY_BARQU ;  A9IW82, TYSY_BART1 ;  Q1LSU0, TYSY_BAUCH ;
DR   Q6MID2, TYSY_BDEBA ;  Q8G3T9, TYSY_BIFLO ;  Q7WP13, TYSY_BORBR ;
DR   Q7W1A9, TYSY_BORPA ;  Q7VUE3, TYSY_BORPE ;  Q2TA32, TYSY_BOVIN ;
DR   P07606, TYSY_BPPHT ;  P00471, TYSY_BPT4  ;  C0QWM9, TYSY_BRAHW ;
DR   Q89G35, TYSY_BRAJA ;  A5EPD3, TYSY_BRASB ;  A4YZC4, TYSY_BRASO ;
DR   C0ZI91, TYSY_BREBN ;  Q2YS22, TYSY_BRUA2 ;  Q57CA9, TYSY_BRUAB ;
DR   A9M657, TYSY_BRUC2 ;  C0RE38, TYSY_BRUMB ;  P67042, TYSY_BRUME ;
DR   A5VRE7, TYSY_BRUO2 ;  B0CHI7, TYSY_BRUSI ;  P67043, TYSY_BRUSU ;
DR   B8D9L8, TYSY_BUCA5 ;  P57515, TYSY_BUCAI ;  Q8K9C3, TYSY_BUCAP ;
DR   B8D7X0, TYSY_BUCAT ;  P59427, TYSY_BUCBP ;  P12461, TYSY_CANAL ;
DR   Q9A6H0, TYSY_CAUCR ;  Q1QUD9, TYSY_CHRSD ;  Q7NZ95, TYSY_CHRVO ;
DR   A8AP42, TYSY_CITK8 ;  Q97EV3, TYSY_CLOAB ;  A6M378, TYSY_CLOB8 ;
DR   B8I0T8, TYSY_CLOCE ;  Q47Y31, TYSY_COLP3 ;  C3PEY5, TYSY_CORA7 ;
DR   Q6NIF2, TYSY_CORDI ;  Q8FR47, TYSY_COREF ;  A4QCI7, TYSY_CORGB ;
DR   Q8NS38, TYSY_CORGL ;  Q4JX59, TYSY_CORJK ;  A9KF61, TYSY_COXBN ;
DR   A9N980, TYSY_COXBR ;  Q83BG2, TYSY_COXBU ;  P0CS13, TYSY_CRYNB ;
DR   P0CS12, TYSY_CRYNJ ;  Q0K889, TYSY_CUPNH ;  Q11VK5, TYSY_CYTH3 ;
DR   Q47II1, TYSY_DECAR ;  C1D070, TYSY_DEIDV ;  A5EVG5, TYSY_DICNV ;
DR   O76511, TYSY_DROME ;  A7ZQT3, TYSY_ECO24 ;  B7UHP4, TYSY_ECO27 ;
DR   B7MLH3, TYSY_ECO45 ;  B7LF04, TYSY_ECO55 ;  P0A886, TYSY_ECO57 ;
DR   B7NVX2, TYSY_ECO7I ;  B7MZC6, TYSY_ECO81 ;  B7LY83, TYSY_ECO8A ;
DR   C4ZZX9, TYSY_ECOBW ;  A8A3W0, TYSY_ECOHS ;  A1AF39, TYSY_ECOK1 ;
DR   Q0TE05, TYSY_ECOL5 ;  P0A885, TYSY_ECOL6 ;  B1IU17, TYSY_ECOLC ;
DR   P0A884, TYSY_ECOLI ;  B7N759, TYSY_ECOLU ;  Q1R7I6, TYSY_ECOUT ;
DR   C5BH86, TYSY_EDWI9 ;  Q89940, TYSY_EHV2  ;  A4WE03, TYSY_ENT38 ;
DR   Q834R3, TYSY_ENTFA ;  A7MR31, TYSY_ENTS8 ;  Q6D8I6, TYSY_ERWCT ;
DR   B7LNI2, TYSY_ESCF3 ;  C4L1C9, TYSY_EXISA ;  A5FJV8, TYSY_FLAJ1 ;
DR   A6GWH3, TYSY_FLAPJ ;  B0TYI1, TYSY_FRAP2 ;  Q14H07, TYSY_FRAT1 ;
DR   A7NB78, TYSY_FRATF ;  Q2A486, TYSY_FRATH ;  A0Q7B4, TYSY_FRATN ;
DR   Q0BMM0, TYSY_FRATO ;  Q5NFK5, TYSY_FRATT ;  A4IXE8, TYSY_FRATW ;
DR   Q8RGP6, TYSY_FUSNN ;  Q5KZ25, TYSY_GEOKA ;  C5DAR2, TYSY_GEOSW ;
DR   A4INY1, TYSY_GEOTN ;  A0LY29, TYSY_GRAFK ;  Q7VMH2, TYSY_HAEDU ;
DR   Q4QM04, TYSY_HAEI8 ;  A5UDH0, TYSY_HAEIE ;  A5UI47, TYSY_HAEIG ;
DR   P44420, TYSY_HAEIN ;  B8F6S2, TYSY_HAEPS ;  Q0I563, TYSY_HAES1 ;
DR   B0UWT7, TYSY_HAES2 ;  Q2SA17, TYSY_HAHCH ;  A1WYP9, TYSY_HALHL ;
DR   C4K7G3, TYSY_HAMD5 ;  P90463, TYSY_HHV8P ;  P12462, TYSY_HSVAT ;
DR   P04818, TYSY_HUMAN ;  Q0C504, TYSY_HYPNA ;  Q5R064, TYSY_IDILO ;
DR   Q9WBI3, TYSY_IIV6  ;  A6WGF9, TYSY_KINRD ;  A6TDG3, TYSY_KLEP7 ;
DR   Q5FKL6, TYSY_LACAC ;  Q03S95, TYSY_LACBA ;  Q039F7, TYSY_LACC3 ;
DR   P00469, TYSY_LACCA ;  Q1GAP2, TYSY_LACDA ;  Q04B29, TYSY_LACDB ;
DR   Q044A1, TYSY_LACGA ;  A8YUW0, TYSY_LACH4 ;  Q74IU3, TYSY_LACJO ;
DR   P19368, TYSY_LACLA ;  Q02Y43, TYSY_LACLS ;  Q88W05, TYSY_LACPL ;
DR   A5VJK9, TYSY_LACRD ;  Q1WU17, TYSY_LACS1 ;  Q38WX8, TYSY_LACSS ;
DR   C1D4I5, TYSY_LARHH ;  Q5X119, TYSY_LEGPA ;  A5II41, TYSY_LEGPC ;
DR   Q5ZRL3, TYSY_LEGPH ;  Q5WSU5, TYSY_LEGPL ;  Q6AFI0, TYSY_LEIXX ;
DR   Q03YZ8, TYSY_LEUMM ;  Q92AD4, TYSY_LISIN ;  C1KWH4, TYSY_LISMC ;
DR   Q71YE1, TYSY_LISMF ;  B8DDM8, TYSY_LISMH ;  Q8Y626, TYSY_LISMO ;
DR   A0AJY0, TYSY_LISW6 ;  Q2W7P4, TYSY_MAGSA ;  Q65VJ8, TYSY_MANSM ;
DR   A1U3D8, TYSY_MARAV ;  A6W1R4, TYSY_MARMS ;  Q6F145, TYSY_MESFL ;
DR   Q11HI0, TYSY_MESSB ;  B7KQG2, TYSY_METC4 ;  Q603S2, TYSY_METCA ;
DR   Q9RAM7, TYSY_METFK ;  B8IF20, TYSY_METNO ;  A2SHH0, TYSY_METPP ;
DR   B8ELI3, TYSY_METSB ;  P07607, TYSY_MOUSE ;  A0QIU1, TYSY_MYCA1 ;
DR   P67045, TYSY_MYCBO ;  A1KMA6, TYSY_MYCBP ;  C1AFM7, TYSY_MYCBT ;
DR   Q9XC19, TYSY_MYCGA ;  P47469, TYSY_MYCGE ;  A4TCI9, TYSY_MYCGI ;
DR   Q9CBW0, TYSY_MYCLE ;  Q6KIQ6, TYSY_MYCMO ;  Q73VZ2, TYSY_MYCPA ;
DR   Q8EV81, TYSY_MYCPE ;  P78029, TYSY_MYCPN ;  Q98Q31, TYSY_MYCPU ;
DR   A0QVR9, TYSY_MYCS2 ;  Q4A611, TYSY_MYCS5 ;  A3PYA8, TYSY_MYCSJ ;
DR   A1UEU8, TYSY_MYCSK ;  Q1BA64, TYSY_MYCSS ;  A5U6B7, TYSY_MYCTA ;
DR   P67044, TYSY_MYCTU ;  A0PQG7, TYSY_MYCUA ;  A1T7P4, TYSY_MYCVP ;
DR   Q5F732, TYSY_NEIG1 ;  O33380, TYSY_NEIGO ;  Q9JT57, TYSY_NEIMA ;
DR   Q9JY72, TYSY_NEIMB ;  A1KVB3, TYSY_NEIMF ;  Q0AHA4, TYSY_NITEC ;
DR   Q82WU3, TYSY_NITEU ;  Q1QJT8, TYSY_NITHX ;  Q3JEI2, TYSY_NITOC ;
DR   Q3SQ36, TYSY_NITWN ;  Q5YPL7, TYSY_NOCFA ;  A1SJ31, TYSY_NOCSJ ;
DR   Q2G6V6, TYSY_NOVAD ;  Q8EQG0, TYSY_OCEIH ;  A6WZV4, TYSY_OCHA4 ;
DR   Q04FR4, TYSY_OENOB ;  B6JB67, TYSY_OLICO ;  Q6YQT0, TYSY_ONYPE ;
DR   A6LIC2, TYSY_PARD8 ;  A7HVX4, TYSY_PARL1 ;  P57808, TYSY_PASMU ;
DR   C6DAE9, TYSY_PECCP ;  Q03F96, TYSY_PEDPA ;  Q7N8U4, TYSY_PHOLL ;
DR   Q6LUM1, TYSY_PHOPR ;  B3QZX0, TYSY_PHYMT ;  P13100, TYSY_PNECA ;
DR   A1VQZ6, TYSY_POLNA ;  Q12CI6, TYSY_POLSJ ;  A4SVT7, TYSY_POLSQ ;
DR   Q7MTB5, TYSY_PORGI ;  Q6A761, TYSY_PROAC ;  Q15P51, TYSY_PSEA6 ;
DR   A6UYE6, TYSY_PSEA7 ;  B7V2Q5, TYSY_PSEA8 ;  Q02U73, TYSY_PSEAB ;
DR   Q9I6F1, TYSY_PSEAE ;  C3K3Q8, TYSY_PSEFS ;  Q3IDN1, TYSY_PSEHT ;
DR   A4Y044, TYSY_PSEMY ;  A5WAK1, TYSY_PSEP1 ;  Q88CN9, TYSY_PSEPK ;
DR   Q87UL4, TYSY_PSESM ;  A4VGL9, TYSY_PSEU5 ;  Q1Q8B2, TYSY_PSYCK ;
DR   A1SS96, TYSY_PSYIN ;  A5WHY0, TYSY_PSYWF ;  Q1LK81, TYSY_RALME ;
DR   Q8Y0U6, TYSY_RALSO ;  P45352, TYSY_RAT   ;  Q2K6G8, TYSY_RHIEC ;
DR   Q1ME82, TYSY_RHIL3 ;  Q98KH9, TYSY_RHILO ;  Q92NQ5, TYSY_RHIME ;
DR   C3MEE8, TYSY_RHISN ;  Q7UID0, TYSY_RHOBA ;  Q21U56, TYSY_RHOFD ;
DR   Q2IYG7, TYSY_RHOP2 ;  Q07PP0, TYSY_RHOP5 ;  Q6N447, TYSY_RHOPA ;
DR   Q211X8, TYSY_RHOPB ;  Q134B1, TYSY_RHOPS ;  A3PLD1, TYSY_RHOS1 ;
DR   Q3J0W9, TYSY_RHOS4 ;  A4WQT6, TYSY_RHOS5 ;  Q0SEI1, TYSY_RHOSR ;
DR   Q168V8, TYSY_ROSDO ;  A1AWQ8, TYSY_RUTMC ;  Q21NW5, TYSY_SACD2 ;
DR   A9MS82, TYSY_SALAR ;  Q57KB6, TYSY_SALCH ;  Q5PEN6, TYSY_SALPA ;
DR   A9N2L7, TYSY_SALPB ;  C0PXI9, TYSY_SALPC ;  Q8Z412, TYSY_SALTI ;
DR   Q8ZMA9, TYSY_SALTY ;  Q9UTI7, TYSY_SCHPO ;  A8GIH7, TYSY_SERP5 ;
DR   A1S3W8, TYSY_SHEAM ;  B8EBR5, TYSY_SHEB2 ;  A3D1U3, TYSY_SHEB5 ;
DR   A6WKP4, TYSY_SHEB8 ;  A9L5M3, TYSY_SHEB9 ;  Q12KG8, TYSY_SHEDO ;
DR   Q07YY3, TYSY_SHEFN ;  B0TIU4, TYSY_SHEHH ;  A3QBR4, TYSY_SHELP ;
DR   Q8EH94, TYSY_SHEON ;  A8H1B4, TYSY_SHEPA ;  A4Y4J1, TYSY_SHEPC ;
DR   B8CQK7, TYSY_SHEPW ;  A0KZP5, TYSY_SHESA ;  A8FSC3, TYSY_SHESH ;
DR   Q0HG85, TYSY_SHESM ;  Q0HSH8, TYSY_SHESR ;  A1RME0, TYSY_SHESW ;
DR   Q31XG0, TYSY_SHIBS ;  Q32C94, TYSY_SHIDS ;  Q0T137, TYSY_SHIF8 ;
DR   P48464, TYSY_SHIFL ;  Q3YY33, TYSY_SHISS ;  P06854, TYSY_SHV21 ;
DR   Q1GFV4, TYSY_SILST ;  A6UB24, TYSY_SINMW ;  Q2NRH3, TYSY_SODGM ;
DR   Q1GTH6, TYSY_SPHAL ;  A5VCW6, TYSY_SPHWW ;  A7X2B3, TYSY_STAA1 ;
DR   A6U1P7, TYSY_STAA2 ;  Q2FH11, TYSY_STAA3 ;  Q2FYK5, TYSY_STAA8 ;
DR   A5ISV8, TYSY_STAA9 ;  Q2YY40, TYSY_STAAB ;  Q5HFZ6, TYSY_STAAC ;
DR   A6QGX8, TYSY_STAAE ;  P67046, TYSY_STAAM ;  P67047, TYSY_STAAN ;
DR   Q6GGY0, TYSY_STAAR ;  Q6G9D4, TYSY_STAAS ;  A8Z406, TYSY_STAAT ;
DR   P0A0M5, TYSY_STAAU ;  P67048, TYSY_STAAW ;  P0C0M4, TYSY_STAEP ;
DR   Q5HMP6, TYSY_STAEQ ;  P0C0M5, TYSY_STAES ;  Q4L6D7, TYSY_STAHJ ;
DR   Q49XN8, TYSY_STAS1 ;  Q3K0J7, TYSY_STRA1 ;  Q8E4L6, TYSY_STRA3 ;
DR   Q8DZ07, TYSY_STRA5 ;  A8AXC2, TYSY_STRGC ;  Q8DUI4, TYSY_STRMU ;
DR   P67051, TYSY_STRP1 ;  Q04LL8, TYSY_STRP2 ;  P0DG66, TYSY_STRP3 ;
DR   Q5XCM3, TYSY_STRP6 ;  C1C631, TYSY_STRP7 ;  Q8P1D1, TYSY_STRP8 ;
DR   Q1JC96, TYSY_STRPB ;  Q1JM80, TYSY_STRPC ;  Q1JHC5, TYSY_STRPD ;
DR   Q1J744, TYSY_STRPF ;  A2RF20, TYSY_STRPG ;  B8ZMQ1, TYSY_STRPJ ;
DR   Q48U25, TYSY_STRPM ;  P67049, TYSY_STRPN ;  P0DG67, TYSY_STRPQ ;
DR   P67050, TYSY_STRR6 ;  A4W0V3, TYSY_STRS2 ;  A3CMU9, TYSY_STRSV ;
DR   A4VUL1, TYSY_STRSY ;  Q5M0S7, TYSY_STRT1 ;  Q5M5B3, TYSY_STRT2 ;
DR   Q03LN3, TYSY_STRTD ;  C1CD36, TYSY_STRZJ ;  C1CJD5, TYSY_STRZP ;
DR   C1CQE7, TYSY_STRZT ;  Q67JQ1, TYSY_SYMTH ;  C5BMA3, TYSY_TERTT ;
DR   Q31I55, TYSY_THICR ;  Q3SH96, TYSY_THIDA ;  B8GN06, TYSY_THISH ;
DR   C4LD19, TYSY_TOLAT ;  A5CWK3, TYSY_VESOH ;  A5F8Y6, TYSY_VIBC3 ;
DR   O66108, TYSY_VIBCH ;  C3LST0, TYSY_VIBCM ;  Q5E7P1, TYSY_VIBF1 ;
DR   A7MXJ9, TYSY_VIBHB ;  Q87SA0, TYSY_VIBPA ;  B7VJ78, TYSY_VIBSL ;
DR   Q8DER9, TYSY_VIBVU ;  Q7MNN6, TYSY_VIBVY ;  P09249, TYSY_VZVD  ;
DR   Q4JQW2, TYSY_VZVO  ;  Q8D2N4, TYSY_WIGBR ;  Q8PP46, TYSY_XANAC ;
DR   Q3BX87, TYSY_XANC5 ;  Q4UR35, TYSY_XANC8 ;  Q8PCE7, TYSY_XANCP ;
DR   Q2NZH9, TYSY_XANOM ;  Q5GWB5, TYSY_XANOR ;  Q6REU8, TYSY_XENNA ;
DR   Q9PB13, TYSY_XYLFA ;  Q87BT4, TYSY_XYLFT ;  P06785, TYSY_YEAST ;
DR   A1JPC9, TYSY_YERE8 ;  A7FFE0, TYSY_YERP3 ;  Q1CAR9, TYSY_YERPA ;
DR   Q8ZHV1, TYSY_YERPE ;  Q1CFB5, TYSY_YERPN ;  A4TLC5, TYSY_YERPP ;
DR   Q667F9, TYSY_YERPS ;  Q9Z671, TYSY_ZYMMO ;
//
ID   2.1.1.46
DE   Isoflavone 4'-O-methyltransferase.
CA   S-adenosyl-L-methionine + an isoflavone = S-adenosyl-L-homocysteine +
CA   a 4'-O-methylisoflavone.
DR   Q84KK6, I4OMT_GLYEC;  Q84KK4, I4OMT_LOTJA;  Q29U70, I4OMT_MEDTR;
DR   O24305, M3OM1_PEA  ;
//
ID   2.1.1.47
DE   Indolepyruvate C-methyltransferase.
AN   Indolepyruvate 3-methyltransferase.
AN   Indolepyruvate methyltransferase.
AN   Indolepyruvic acid methyltransferase.
CA   S-adenosyl-L-methionine + (indol-3-yl)pyruvate = S-adenosyl-L-
CA   homocysteine + (S)-3-(indol-3-yl)-2-oxobutanoate.
//
ID   2.1.1.48
DE   Transferred entry: 2.1.1.181, 2.1.1.182, 2.1.1.183 and 2.1.1.184.
//
ID   2.1.1.49
DE   Amine N-methyltransferase.
AN   Arylamine N-methyltransferase.
AN   Nicotine N-methyltransferase.
AN   Tryptamine N-methyltransferase.
CA   S-adenosyl-L-methionine + an amine = S-adenosyl-L-homocysteine +
CA   a methylated amine.
CC   -!- A wide range of primary, secondary, and tertiary amines can act as
CC       acceptors, including tryptamine, aniline, nicotine and a variety of
CC       drugs and other xenobiotics.
CC   -!- Formerly EC 2.1.1.81.
DR   O95050, INMT_HUMAN ;  P40936, INMT_MOUSE ;  Q5RFR7, INMT_PONAB ;
DR   O97972, INMT_RABIT ;
//
ID   2.1.1.50
DE   Loganate O-methyltransferase.
CA   S-adenosyl-L-methionine + loganate = S-adenosyl-L-homocysteine + loganin.
CC   -!- Also acts on secologanate.
CC   -!- Methylates the 11-carboxy group of the monoterpenoid loganate.
//
ID   2.1.1.51
DE   Transferred entry: 2.1.1.187 and 2.1.1.188.
//
ID   2.1.1.52
DE   Transferred entry: 2.1.1.171, 2.1.1.172, 2.1.1.173 and 2.1.1.174.
//
ID   2.1.1.53
DE   Putrescine N-methyltransferase.
CA   S-adenosyl-L-methionine + putrescine = S-adenosyl-L-homocysteine +
CA   N-methylputrescine.
PR   PROSITE; PDOC01033;
DR   Q42963, PMT1_TOBAC ;  Q9SEH7, PMT2_TOBAC ;  Q9SEH5, PMT3_TOBAC ;
DR   Q9SEH4, PMT4_TOBAC ;
//
ID   2.1.1.54
DE   Deoxycytidylate C-methyltransferase.
CA   5,10-methylenetetrahydrofolate + dCMP = dihydrofolate + deoxy-5-
CA   methylcytidylate.
CC   -!- dCMP is methylated by formaldehyde in the presence of
CC       tetrahydrofolate.
CC   -!- CMP, dCTP and CTP can act as acceptor, more slowly.
//
ID   2.1.1.55
DE   tRNA (adenine-N(6)-)-methyltransferase.
CA   S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA
CA   containing N(6)-methyladenine.
DR   A3N3J4, TRMN6_ACTP2;  B3H2W9, TRMN6_ACTP7;  A6VKA4, TRMN6_ACTSZ;
DR   A0KPC4, TRMN6_AERHH;  A4SRS5, TRMN6_AERS4;  C6AQR4, TRMN6_AGGAN;
DR   B6EMW5, TRMN6_ALISL;  B4RSB8, TRMN6_ALTMD;  Q5LCS1, TRMN6_BACFN;
DR   Q64TX7, TRMN6_BACFR;  Q8A9H7, TRMN6_BACTN;  A6L532, TRMN6_BACV8;
DR   A8AD10, TRMN6_CITK8;  Q11RK8, TRMN6_CYTH3;  C6CB42, TRMN6_DICDC;
DR   C6CNL2, TRMN6_DICZE;  C6VS84, TRMN6_DYAFD;  A7ZQ20, TRMN6_ECO24;
DR   B7UH15, TRMN6_ECO27;  B7MIR0, TRMN6_ECO45;  B7LDG8, TRMN6_ECO55;
DR   Q8XA22, TRMN6_ECO57;  B5Z149, TRMN6_ECO5E;  C6UQY1, TRMN6_ECO5T;
DR   B7NRM8, TRMN6_ECO7I;  B7MYK8, TRMN6_ECO81;  B7M8I9, TRMN6_ECO8A;
DR   C5W7S9, TRMN6_ECOBD;  C6UBI3, TRMN6_ECOBR;  C4ZYJ8, TRMN6_ECOBW;
DR   B1XBQ2, TRMN6_ECODH;  A8A386, TRMN6_ECOHS;  A1AEA5, TRMN6_ECOK1;
DR   Q0TER3, TRMN6_ECOL5;  Q8FF14, TRMN6_ECOL6;  B1IVQ2, TRMN6_ECOLC;
DR   P31825, TRMN6_ECOLI;  B7N6G4, TRMN6_ECOLU;  B6I5E9, TRMN6_ECOSE;
DR   B1LP88, TRMN6_ECOSM;  Q1R8F7, TRMN6_ECOUT;  C5BAI6, TRMN6_EDWI9;
DR   A4WDE6, TRMN6_ENT38;  A7MH06, TRMN6_ENTS8;  Q6D211, TRMN6_ERWCT;
DR   B2VI36, TRMN6_ERWT9;  B7LUY9, TRMN6_ESCF3;  C6X2D2, TRMN6_FLAB3;
DR   A5FKD7, TRMN6_FLAJ1;  A6GWI6, TRMN6_FLAPJ;  A0LXM6, TRMN6_GRAFK;
DR   Q4QNC1, TRMN6_HAEI8;  A5UA66, TRMN6_HAEIE;  A5UGT6, TRMN6_HAEIG;
DR   P44702, TRMN6_HAEIN;  B8F678, TRMN6_HAEPS;  Q0I4T7, TRMN6_HAES1;
DR   B0UWL8, TRMN6_HAES2;  B5XNG1, TRMN6_KLEP3;  A6TCI9, TRMN6_KLEP7;
DR   Q65W50, TRMN6_MANSM;  A6LD46, TRMN6_PARD8;  Q9CJZ9, TRMN6_PASMU;
DR   C6DC08, TRMN6_PECCP;  C6Y2G0, TRMN6_PEDHD;  Q7N1W7, TRMN6_PHOLL;
DR   Q6LUN9, TRMN6_PHOPR;  B2RK25, TRMN6_PORG3;  Q7MVG0, TRMN6_PORGI;
DR   B4F055, TRMN6_PROMH;  Q15NR8, TRMN6_PSEA6;  Q3IG80, TRMN6_PSEHT;
DR   A9MGW2, TRMN6_SALAR;  Q57L59, TRMN6_SALCH;  B5QTV6, TRMN6_SALEP;
DR   B5RD57, TRMN6_SALG2;  Q5PNB8, TRMN6_SALPA;  A9N0W9, TRMN6_SALPB;
DR   C0PVY6, TRMN6_SALPC;  B5BAS2, TRMN6_SALPK;  Q8Z4J9, TRMN6_SALTI;
DR   Q8ZMX8, TRMN6_SALTY;  A8GI34, TRMN6_SERP5;  A1S987, TRMN6_SHEAM;
DR   B8E5T2, TRMN6_SHEB2;  A3D0V3, TRMN6_SHEB5;  A6WS64, TRMN6_SHEB8;
DR   A9L1L1, TRMN6_SHEB9;  Q12R91, TRMN6_SHEDO;  Q087P4, TRMN6_SHEFN;
DR   B0TUD3, TRMN6_SHEHH;  A3QAZ2, TRMN6_SHELP;  Q8EI95, TRMN6_SHEON;
DR   A8H0P3, TRMN6_SHEPA;  A4Y3T4, TRMN6_SHEPC;  B8CU29, TRMN6_SHEPW;
DR   A0L0I8, TRMN6_SHESA;  A8FRM9, TRMN6_SHESH;  Q0HM44, TRMN6_SHESM;
DR   Q0HRP2, TRMN6_SHESR;  A1RN54, TRMN6_SHESW;  B1KF36, TRMN6_SHEWM;
DR   B2TYI8, TRMN6_SHIB3;  Q31XR1, TRMN6_SHIBS;  Q32CU6, TRMN6_SHIDS;
DR   Q0T1T1, TRMN6_SHIF8;  Q83QI2, TRMN6_SHIFL;  Q3YYU0, TRMN6_SHISS;
DR   C4LCN4, TRMN6_TOLAT;  Q119M4, TRMN6_TRIEI;  Q9KU62, TRMN6_VIBCH;
DR   C3LSR6, TRMN6_VIBCM;  Q5E7Q6, TRMN6_VIBF1;  B5F9T8, TRMN6_VIBFM;
DR   A7MXM2, TRMN6_VIBHB;  Q87SB8, TRMN6_VIBPA;  B7VJ58, TRMN6_VIBSL;
DR   Q8DEQ3, TRMN6_VIBVU;  Q7MNQ4, TRMN6_VIBVY;  A1JKJ4, TRMN6_YERE8;
DR   A7FFT0, TRMN6_YERP3;  Q1C564, TRMN6_YERPA;  B2KA56, TRMN6_YERPB;
DR   Q74SR9, TRMN6_YERPE;  A9R3Z3, TRMN6_YERPG;  Q1CKF3, TRMN6_YERPN;
DR   A4TKY7, TRMN6_YERPP;  Q667U2, TRMN6_YERPS;  B1JRB8, TRMN6_YERPY;
//
ID   2.1.1.56
DE   mRNA (guanine-N(7)-)-methyltransferase.
AN   Guanine-7-methyltransferase.
AN   Messenger ribonucleate guanine 7-methyltransferase.
AN   Messenger RNA guanine 7-methyltransferase.
CA   S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine +
CA   m(7)G(5')pppR-RNA.
CC   -!- Adds an N(7)-methylguanine cap to mRNA.
CC   -!- R may be guanosine or adenosine.
DR   P11079, LMBD2_REOVD;  Q91RA4, LMBD2_REOVJ;  Q91RA6, LMBD2_REOVL;
DR   Q9QSP0, L_ABLVB    ;  Q8JTG9, L_ABLVH    ;  Q2Y2L8, L_AMPV1    ;
DR   Q8JMN0, L_BDV      ;  P52639, L_BDVV     ;  Q9E784, L_BEFVB    ;
DR   O91940, L_BRSVA    ;  P24658, L_CDVO     ;  P13179, L_CHAV     ;
DR   Q6DN67, L_CPSVP    ;  A4UHQ2, L_EBLV1    ;  A4UHQ7, L_EBLV2    ;
DR   Q91DD4, L_EBORE    ;  Q8JPX5, L_EBORR    ;  Q66802, L_EBOSM    ;
DR   Q5XX01, L_EBOSU    ;  Q6V1Q2, L_EBOZ5    ;  Q05318, L_EBOZM    ;
DR   O89344, L_HENDH    ;  Q77SJ8, L_HIRRV    ;  Q6WB93, L_HMPVC    ;
DR   P20894, L_HRSV     ;  P28887, L_HRSVA    ;  O36635, L_HRSVB    ;
DR   Q9IWW8, L_HRSVL    ;  Q82707, L_IHNVO    ;  Q82685, L_IHNVW    ;
DR   Q5K2K3, L_ISFV     ;  Q8B0U2, L_LBVAV    ;  Q4W382, L_LNYV3    ;
DR   Q1PD54, L_MABVA    ;  P31352, L_MABVM    ;  Q6UY63, L_MABVO    ;
DR   P35262, L_MABVP    ;  Q1PDC4, L_MABVR    ;  P35975, L_MEASA    ;
DR   Q9WMB3, L_MEASC    ;  P12576, L_MEASE    ;  Q8BCV9, L_MILVL    ;
DR   Q6E0W6, L_MMVR     ;  P0C568, L_MOKV     ;  Q50EW2, L_MPV15    ;
DR   P30929, L_MUMPM    ;  P11205, L_NDVB     ;  Q9DLD3, L_NDVB1    ;
DR   Q997F0, L_NIPAV    ;  P35946, L_PHODV    ;  P26676, L_PI2HT    ;
DR   P12577, L_PI3H4    ;  Q4F8Z9, L_RABVA    ;  Q66T60, L_RABVB    ;
DR   Q0GBX5, L_RABVD    ;  A3F5L9, L_RABVE    ;  Q8B6J5, L_RABVH    ;
DR   A3RM23, L_RABVI    ;  Q9IPJ5, L_RABVN    ;  P11213, L_RABVP    ;
DR   Q0GBY0, L_RABVR    ;  P16289, L_RABVS    ;  P41357, L_RINDR    ;
DR   O10378, L_RYSV     ;  Q9DUD8, L_SENDA    ;  P06829, L_SENDE    ;
DR   Q06996, L_SENDF    ;  O55528, L_SENDO    ;  P06447, L_SENDZ    ;
DR   Q9QJT4, L_SHRV     ;  P35341, L_SV41     ;  Q88434, L_SV5      ;
DR   Q03396, L_SV5WR    ;  Q91DR9, L_SVCV     ;  P31332, L_SYNV     ;
DR   Q5GA85, L_TAVCV    ;  P03523, L_VSIVA    ;  Q8B0H0, L_VSIVC    ;
DR   Q98776, L_VSIVM    ;  Q8B0I0, L_VSIVN    ;  Q8B0H5, L_VSIVS    ;
DR   P13615, L_VSNJH    ;  P16379, L_VSNJO    ;  Q9LHQ7, MCES1_ARATH;
DR   Q6Z9U7, MCES1_ORYSJ;  Q5HZ60, MCES2_ARATH;  Q6K833, MCES2_ORYSJ;
DR   Q754U7, MCES_ASHGO ;  A1CT57, MCES_ASPCL ;  Q4WN42, MCES_ASPFU ;
DR   A2QVS9, MCES_ASPNC ;  Q2UM19, MCES_ASPOR ;  Q61E36, MCES_CAEBR ;
DR   Q9XVS1, MCES_CAEEL ;  Q5ADX5, MCES_CANAL ;  Q6FML4, MCES_CANGA ;
DR   P0CO65, MCES_CRYNB ;  P0CO64, MCES_CRYNJ ;  Q1MTD3, MCES_DANRE ;
DR   Q6BMH4, MCES_DEBHA ;  Q9VJQ4, MCES_DROME ;  Q8SR66, MCES_ENCCU ;
DR   O72908, MCES_FOWPN ;  O43148, MCES_HUMAN ;  Q6CKI0, MCES_KLULA ;
DR   A5E032, MCES_LODEL ;  Q4R7K1, MCES_MACFA ;  A4R8D7, MCES_MAGO7 ;
DR   Q9D0L8, MCES_MOUSE ;  A1DMG9, MCES_NEOFI ;  A5DDJ4, MCES_PICGU ;
DR   A3GEV2, MCES_PICST ;  Q5U2U7, MCES_RAT   ;  O74880, MCES_SCHPO ;
DR   Q08512, MCES_SWPVK ;  O57215, MCES_VACCA ;  P20980, MCES_VACCC ;
DR   P04318, MCES_VACCW ;  P33808, MCES_VAR67 ;  Q9I8S2, MCES_XENLA ;
DR   Q28FT4, MCES_XENTR ;  Q6CC11, MCES_YARLI ;  P32783, MCES_YEAST ;
DR   Q9QB92, MCES_YMTV5 ;  Q5UQX1, MCE_MIMIV  ;  P27909, POLG_DEN1B ;
DR   P33478, POLG_DEN1S ;  P17763, POLG_DEN1W ;  P29990, POLG_DEN26 ;
DR   P29991, POLG_DEN27 ;  P14337, POLG_DEN28 ;  P07564, POLG_DEN2J ;
DR   P14340, POLG_DEN2N ;  P12823, POLG_DEN2P ;  Q9WDA6, POLG_DEN2Q ;
DR   Q99D35, POLG_DEN3C ;  Q5UB51, POLG_DEN3I ;  Q6YMS3, POLG_DEN3M ;
DR   P27915, POLG_DEN3P ;  Q6YMS4, POLG_DEN3S ;  P09866, POLG_DEN4D ;
DR   Q2YHF2, POLG_DEN4H ;  Q58HT7, POLG_DEN4P ;  Q5UCB8, POLG_DEN4S ;
DR   Q2YHF0, POLG_DEN4T ;  P27395, POLG_JAEV1 ;  P19110, POLG_JAEV5 ;
DR   P32886, POLG_JAEVJ ;  P14335, POLG_KUNJM ;  P29837, POLG_LANVT ;
DR   P22338, POLG_LIV   ;  P33515, POLG_MCFA  ;  P05769, POLG_MVEV5 ;
DR   Q04538, POLG_POWVL ;  P09732, POLG_STEVM ;  Q01299, POLG_TBEVH ;
DR   P07720, POLG_TBEVS ;  P14336, POLG_TBEVW ;  P06935, POLG_WNV   ;
DR   P03314, POLG_YEFV1 ;  Q6DV88, POLG_YEFVA ;  Q6J3P1, POLG_YEFVC ;
DR   Q074N0, POLG_YEFVE ;  Q89277, POLG_YEFVF ;  Q98803, POLG_YEFVI ;
DR   Q1X881, POLG_YEFVN ;  Q9YRV3, POLG_YEFVT ;  Q1X880, POLG_YEFVU ;
DR   Q8VA43, VP1_AQRVA  ;  Q8JU62, VP1_AQRVC  ;  B2BND9, VP1_AQRVG  ;
DR   O56043, VP2_RRSVT  ;  Q9INI4, VP3_BAVJK  ;  Q7TDB4, VP3_MYRV9  ;
DR   Q3ZK57, VP3_ROT41  ;  B1NKR5, VP3_ROTAD  ;  A9Q1K9, VP3_ROTB2  ;
DR   A7J3A0, VP3_ROTBN  ;  Q65526, VP3_ROTBS  ;  Q6WAT6, VP3_ROTBU  ;
DR   Q6WNV6, VP3_ROTCC  ;  Q6WNV7, VP3_ROTEL  ;  A4ZCW6, VP3_ROTH3  ;
DR   Q6WNW3, VP3_ROTH6  ;  B1NKR1, VP3_ROTH7  ;  Q82041, VP3_ROTHC  ;
DR   Q6WNW5, VP3_ROTHD  ;  Q9QNB1, VP3_ROTHK  ;  B1NKS7, VP3_ROTHL  ;
DR   B1NKT1, VP3_ROTHP  ;  A7J392, VP3_ROTHS  ;  B1NKT9, VP3_ROTHT  ;
DR   Q91HJ9, VP3_ROTHU  ;  Q6WVH5, VP3_ROTHW  ;  Q45UF7, VP3_ROTJ1  ;
DR   Q6WNV8, VP3_ROTP5  ;  P26192, VP3_ROTPC  ;  Q8BB04, VP3_ROTRF  ;
DR   P15736, VP3_ROTS1  ;  A2T3S5, VP3_ROTSH  ;  B3F2X7, VP3_ROTTU  ;
DR   B2BMF9, VP3_ROTW3  ;  B1NKU3, VP3_ROTWI  ;  A7J3A4, VP3_ROTYO  ;
DR   Q91ID8, VP4_LDCPR  ;  Q2Y0E6, VP5_APRVF  ;
//
ID   2.1.1.57
DE   mRNA (nucleoside-2'-O-)-methyltransferase.
AN   mRNA (adenosine-2'-O-)-methyltransferase.
CA   S-adenosyl-L-methionine + m(7)G(5')pppR-RNA = S-adenosyl-L-homocysteine +
CA   m(7)G(5')pppRm-RNA.
CC   -!- Adds an 2'-O-methylpurine cap to mRNA.
CC   -!- R may be guanosine or adenosine.
CC   -!- Formerly EC 2.1.1.58.
DR   P15916, MCE_FOWPN  ;  P68544, MCE_MYXVL  ;  P68545, MCE_MYXVU  ;
DR   P19748, MCE_SHEVK  ;  P23334, MCE_SWPVK  ;  Q76ZT1, MCE_VACCA  ;
DR   P21033, MCE_VACCC  ;  P07617, MCE_VACCW  ;  P33052, MCE_VAR67  ;
DR   A8XYX2, MTR1A_CAEBR;  D2HRF1, MTR1_AILME ;  A2VE39, MTR1_BOVIN ;
DR   Q9NAA5, MTR1_CAEEL ;  Q803R5, MTR1_DANRE ;  Q54WR1, MTR1_DICDI ;
DR   Q9W4N2, MTR1_DROME ;  Q8N1G2, MTR1_HUMAN ;  A4HQI9, MTR1_LEIBR ;
DR   Q4Q089, MTR1_LEIMA ;  Q9DBC3, MTR1_MOUSE ;  Q5R981, MTR1_PONAB ;
DR   Q5U2Z5, MTR1_RAT   ;  Q38AH0, MTR1_TRYB2 ;  Q4E123, MTR1_TRYCR ;
DR   Q6GQ76, MTR1_XENLA ;  P27909, POLG_DEN1B ;  P33478, POLG_DEN1S ;
DR   P17763, POLG_DEN1W ;  P29990, POLG_DEN26 ;  P29991, POLG_DEN27 ;
DR   P14337, POLG_DEN28 ;  P07564, POLG_DEN2J ;  P14340, POLG_DEN2N ;
DR   P12823, POLG_DEN2P ;  Q9WDA6, POLG_DEN2Q ;  Q99D35, POLG_DEN3C ;
DR   Q5UB51, POLG_DEN3I ;  Q6YMS3, POLG_DEN3M ;  P27915, POLG_DEN3P ;
DR   Q6YMS4, POLG_DEN3S ;  P09866, POLG_DEN4D ;  Q2YHF2, POLG_DEN4H ;
DR   Q58HT7, POLG_DEN4P ;  Q5UCB8, POLG_DEN4S ;  Q2YHF0, POLG_DEN4T ;
DR   P27395, POLG_JAEV1 ;  P19110, POLG_JAEV5 ;  P32886, POLG_JAEVJ ;
DR   P14335, POLG_KUNJM ;  P29837, POLG_LANVT ;  P22338, POLG_LIV   ;
DR   P33515, POLG_MCFA  ;  P05769, POLG_MVEV5 ;  Q04538, POLG_POWVL ;
DR   P09732, POLG_STEVM ;  Q01299, POLG_TBEVH ;  P07720, POLG_TBEVS ;
DR   P14336, POLG_TBEVW ;  P06935, POLG_WNV   ;  P03314, POLG_YEFV1 ;
DR   Q6DV88, POLG_YEFVA ;  Q6J3P1, POLG_YEFVC ;  Q074N0, POLG_YEFVE ;
DR   Q89277, POLG_YEFVF ;  Q98803, POLG_YEFVI ;  Q1X881, POLG_YEFVN ;
DR   Q9YRV3, POLG_YEFVT ;  Q1X880, POLG_YEFVU ;
//
ID   2.1.1.58
DE   Transferred entry: 2.1.1.57.
//
ID   2.1.1.59
DE   [Cytochrome c]-lysine N-methyltransferase.
AN   Cytochrome c (lysine) methyltransferase.
AN   Cytochrome c methyltransferase.
AN   Cytochrome c-specific protein methylase III.
AN   Cytochrome c-specific protein-lysine methyltransferase.
CA   S-adenosyl-L-methionine + [cytochrome c]-L-lysine = S-adenosyl-L-
CA   homocysteine + [cytochrome c]-N(6)-methyl-L-lysine.
DR   Q756K8, CTM1_ASHGO ;  Q6FR37, CTM1_CANGA ;  Q6CMC0, CTM1_KLULA ;
DR   P38818, CTM1_YEAST ;
//
ID   2.1.1.60
DE   Calmodulin-lysine N-methyltransferase.
CA   S-adenosyl-L-methionine + calmodulin L-lysine = S-adenosyl-L-homocysteine
CA   + calmodulin N(6)-methyl-L-lysine.
DR   Q7Z624, CMKMT_HUMAN;  Q3U2J5, CMKMT_MOUSE;  B0K012, CMKMT_RAT  ;
DR   Q6GQ33, CMKMT_XENLA;
//
ID   2.1.1.61
DE   tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase.
CA   S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA
CA   containing 5-methylaminomethyl-2-thiouridylate.
CC   -!- Specific for the terminal methyl group of 5-methylaminomethyl-2-
CC       thiouridylate.
DR   A1TRM7, MNMC_ACIAC ;  Q6F7Y9, MNMC_ACIAD ;  B2HYP8, MNMC_ACIBC ;
DR   A3M8T4, MNMC_ACIBT ;  B0V636, MNMC_ACIBY ;  A1W6V9, MNMC_ACISJ ;
DR   A3N0L8, MNMC_ACTP2 ;  B0BPE2, MNMC_ACTPJ ;  A6VMR0, MNMC_ACTSZ ;
DR   A0KJJ9, MNMC_AERHH ;  A4SNE3, MNMC_AERS4 ;  Q5NY30, MNMC_AROAE ;
DR   A1K5J4, MNMC_AZOSB ;  Q2KVJ9, MNMC_BORA1 ;  Q7WFU7, MNMC_BORBR ;
DR   Q7W4D9, MNMC_BORPA ;  A9I518, MNMC_BORPD ;  B1YQ54, MNMC_BURA4 ;
DR   Q1BZN5, MNMC_BURCA ;  B1K1H7, MNMC_BURCC ;  A0K2U3, MNMC_BURCH ;
DR   Q0BJQ6, MNMC_BURCM ;  A9AJC5, MNMC_BURM1 ;  A3MQF7, MNMC_BURM7 ;
DR   A2S6N9, MNMC_BURM9 ;  Q62FV6, MNMC_BURMA ;  A1V8X2, MNMC_BURMS ;
DR   A3NPL7, MNMC_BURP0 ;  Q3JXS0, MNMC_BURP1 ;  A3N3Y7, MNMC_BURP6 ;
DR   B2JJN6, MNMC_BURP8 ;  B2T7N8, MNMC_BURPP ;  Q63Z34, MNMC_BURPS ;
DR   Q39L16, MNMC_BURS3 ;  Q2T2K1, MNMC_BURTA ;  A4J9Z5, MNMC_BURVG ;
DR   Q13SL2, MNMC_BURXL ;  A7ZEX8, MNMC_CAMC1 ;  A0RQ83, MNMC_CAMFF ;
DR   A7I2T7, MNMC_CAMHC ;  A8FMX4, MNMC_CAMJ8 ;  A7H2B2, MNMC_CAMJD ;
DR   Q9PN30, MNMC_CAMJE ;  A1W0Q3, MNMC_CAMJJ ;  Q5HTJ5, MNMC_CAMJR ;
DR   Q9AA58, MNMC_CAUCR ;  B0SVF8, MNMC_CAUSK ;  Q1QZP3, MNMC_CHRSD ;
DR   Q7NWN9, MNMC_CHRVO ;  A8ADQ4, MNMC_CITK8 ;  Q47XJ9, MNMC_COLP3 ;
DR   Q0KBK6, MNMC_CUPNH ;  Q472D5, MNMC_CUPPJ ;  Q47C51, MNMC_DECAR ;
DR   A9C3G2, MNMC_DELAS ;  A5EWE5, MNMC_DICNV ;  A7ZPE0, MNMC_ECO24 ;
DR   Q8XCQ7, MNMC_ECO57 ;  B1X935, MNMC_ECODH ;  A8A2J3, MNMC_ECOHS ;
DR   A1ADH3, MNMC_ECOK1 ;  Q0TFC2, MNMC_ECOL5 ;  Q8FFH0, MNMC_ECOL6 ;
DR   B1IXC1, MNMC_ECOLC ;  P77182, MNMC_ECOLI ;  B1LLT0, MNMC_ECOSM ;
DR   Q1R988, MNMC_ECOUT ;  A4WCV7, MNMC_ENT38 ;  A7MH59, MNMC_ENTS8 ;
DR   Q6D2N1, MNMC_ERWCT ;  Q7VM59, MNMC_HAEDU ;  Q4QKP6, MNMC_HAEI8 ;
DR   A5UCC9, MNMC_HAEIE ;  A5UEH1, MNMC_HAEIG ;  P44246, MNMC_HAEIN ;
DR   Q0I2W9, MNMC_HAES1 ;  B0UT85, MNMC_HAES2 ;  Q2SD50, MNMC_HAHCH ;
DR   Q0BX22, MNMC_HYPNA ;  Q5QUE0, MNMC_IDILO ;  A6TC10, MNMC_KLEP7 ;
DR   Q5X531, MNMC_LEGPA ;  A5IC27, MNMC_LEGPC ;  Q5ZVA8, MNMC_LEGPH ;
DR   Q5WWF9, MNMC_LEGPL ;  Q04VP5, MNMC_LEPBJ ;  Q04XS7, MNMC_LEPBL ;
DR   B1Y222, MNMC_LEPCP ;  Q72UK9, MNMC_LEPIC ;  Q8F0E4, MNMC_LEPIN ;
DR   A0LA84, MNMC_MAGSM ;  Q65S61, MNMC_MANSM ;  A1TZU2, MNMC_MARAV ;
DR   Q0ALP0, MNMC_MARMM ;  A6W0S5, MNMC_MARMS ;  Q1H1H9, MNMC_METFK ;
DR   A2SH83, MNMC_METPP ;  Q2Y7P9, MNMC_NITMU ;  Q9CNT7, MNMC_PASMU ;
DR   Q7N2A3, MNMC_PHOLL ;  Q6LNT9, MNMC_PHOPR ;  A1VQ03, MNMC_POLNA ;
DR   Q12B26, MNMC_POLSJ ;  Q48LF6, MNMC_PSE14 ;  Q15QE8, MNMC_PSEA6 ;
DR   A6V1X0, MNMC_PSEA7 ;  Q02QU5, MNMC_PSEAB ;  Q9HYF0, MNMC_PSEAE ;
DR   Q1IDB9, MNMC_PSEE4 ;  Q4K8K9, MNMC_PSEF5 ;  Q3IF34, MNMC_PSEHT ;
DR   A4XXB7, MNMC_PSEMY ;  A5W7H7, MNMC_PSEP1 ;  Q3K8R9, MNMC_PSEPF ;
DR   B0KTW1, MNMC_PSEPG ;  Q88M24, MNMC_PSEPK ;  B1J5F1, MNMC_PSEPW ;
DR   Q886E0, MNMC_PSESM ;  Q4ZPZ9, MNMC_PSEU2 ;  A4VMX4, MNMC_PSEU5 ;
DR   Q4FR09, MNMC_PSYA2 ;  Q1Q999, MNMC_PSYCK ;  A1SW96, MNMC_PSYIN ;
DR   A5WGY8, MNMC_PSYWF ;  Q1LM60, MNMC_RALME ;  Q8XYP9, MNMC_RALSO ;
DR   Q21WM8, MNMC_RHOFD ;  Q21KP6, MNMC_SACD2 ;  A9MJ47, MNMC_SALAR ;
DR   Q57LX5, MNMC_SALCH ;  Q5PCW7, MNMC_SALPA ;  A9N465, MNMC_SALPB ;
DR   Q8Z4Z3, MNMC_SALTI ;  Q8ZNB2, MNMC_SALTY ;  A8GH77, MNMC_SERP5 ;
DR   A1S7K4, MNMC_SHEAM ;  A3D671, MNMC_SHEB5 ;  A6WQ09, MNMC_SHEB8 ;
DR   A9KTV2, MNMC_SHEB9 ;  Q12P60, MNMC_SHEDO ;  Q084S3, MNMC_SHEFN ;
DR   B0TL07, MNMC_SHEHH ;  A3QFM9, MNMC_SHELP ;  Q8ECR0, MNMC_SHEON ;
DR   A8H2Z3, MNMC_SHEPA ;  A4Y884, MNMC_SHEPC ;  A0KV89, MNMC_SHESA ;
DR   A8FTT1, MNMC_SHESH ;  Q0HKB8, MNMC_SHESM ;  Q0HWM0, MNMC_SHESR ;
DR   A1RIA5, MNMC_SHESW ;  B1KKR3, MNMC_SHEWM ;  B2TWA6, MNMC_SHIB3 ;
DR   Q31YD4, MNMC_SHIBS ;  Q32DL2, MNMC_SHIDS ;  Q0T2G1, MNMC_SHIF8 ;
DR   Q83QQ8, MNMC_SHIFL ;  Q3YZN7, MNMC_SHISS ;  Q31JE7, MNMC_THICR ;
DR   Q3SID4, MNMC_THIDA ;  A1WH84, MNMC_VEREI ;  A5F6E9, MNMC_VIBC3 ;
DR   Q9KQ91, MNMC_VIBCH ;  C3LP59, MNMC_VIBCM ;  Q5E450, MNMC_VIBF1 ;
DR   A7MS81, MNMC_VIBHB ;  Q87MN6, MNMC_VIBPA ;  Q8DB38, MNMC_VIBVU ;
DR   Q7MIT5, MNMC_VIBVY ;  A1JKL6, MNMC_YERE8 ;  A7FGL1, MNMC_YERP3 ;
DR   Q1C669, MNMC_YERPA ;  B2K8I4, MNMC_YERPB ;  Q8ZD36, MNMC_YERPE ;
DR   A9R7V8, MNMC_YERPG ;  Q1CHL1, MNMC_YERPN ;  A4TM73, MNMC_YERPP ;
DR   Q668W0, MNMC_YERPS ;  B1JGH2, MNMC_YERPY ;
//
ID   2.1.1.62
DE   mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase.
CA   S-adenosyl-L-methionine + m(7)G(5')pppAm = S-adenosyl-L-homocysteine +
CA   m(7)G(5')pppm(6)Am.
CC   -!- mRNA containing an N(6),2'-O-dimethyladenosine cap.
PR   PROSITE; PDOC51143;
DR   P41833, IME4_YEAST ;  O82486, MTA70_ARATH;  Q9VCE6, MTA70_DROME;
DR   Q86U44, MTA70_HUMAN;  Q2HVD6, MTA70_MEDTR;  Q8C3P7, MTA70_MOUSE;
DR   Q6EU10, MTA70_ORYSJ;
//
ID   2.1.1.63
DE   Methylated-DNA--[protein]-cysteine S-methyltransferase.
AN   6-O-methylguanine-DNA methyltransferase.
AN   O-6-methylguanine-DNA-alkyltransferase.
CA   DNA (containing 6-O-methylguanine) + protein L-cysteine = DNA (without
CA   6-O-methylguanine) + protein S-methyl-L-cysteine.
CC   -!- This protein is involved in the repair of alkylated DNA.
CC   -!- It acts only on the alkylated DNA (cf. EC 3.2.2.20 and EC 3.2.2.21).
CC   -!- This enzyme catalyzes only one turnover and therefore is not strictly
CC       catalytic.
PR   PROSITE; PDOC00320;
DR   P19220, ADAB_BACSU ;  P06134, ADA_ECOLI  ;  P26189, ADA_SALTY  ;
DR   P29177, MGMT_BOVIN ;  Q5A0Y8, MGMT_CANAL ;  Q6TDU1, MGMT_CANFA ;
DR   Q6FNR0, MGMT_CANGA ;  P26186, MGMT_CRIGR ;  Q6BVY4, MGMT_DEBHA ;
DR   P16455, MGMT_HUMAN ;  Q6CPW2, MGMT_KLULA ;  A5E7M8, MGMT_LODEL ;
DR   Q5UNU9, MGMT_MIMIV ;  P26187, MGMT_MOUSE ;  A3LZM4, MGMT_PICST ;
DR   P24528, MGMT_RAT   ;  A6ZXD3, MGMT_YEAS7 ;  P26188, MGMT_YEAST ;
DR   O27970, OGT_ARCFU  ;  P11742, OGT_BACSU  ;  P0AFH0, OGT_ECOLI  ;
DR   P44687, OGT_HAEIN  ;  Q8TI34, OGT_METAC  ;  Q46EW4, OGT_METBF  ;
DR   Q58924, OGT_METJA  ;  Q8TZ11, OGT_METKA  ;  Q8PY44, OGT_METMA  ;
DR   A4YH39, OGT_METS5  ;  O26715, OGT_METTH  ;  P0A697, OGT_MYCBO  ;
DR   P52982, OGT_MYCLE  ;  Q9ZET8, OGT_MYCPA  ;  P0A696, OGT_MYCTU  ;
DR   Q9V1N7, OGT_PYRAB  ;  O93728, OGT_PYRAE  ;  Q8TZV2, OGT_PYRFU  ;
DR   O59499, OGT_PYRHO  ;  O74023, OGT_PYRKO  ;  P0A2U1, OGT_SALTI  ;
DR   P0A2U0, OGT_SALTY  ;  P0AFH1, OGT_SHIFL  ;  Q4J9C6, OGT_SULAC  ;
DR   C3N1B4, OGT_SULIA  ;  C4KKV8, OGT_SULIK  ;  C3MKT6, OGT_SULIL  ;
DR   C3MUC6, OGT_SULIM  ;  C3NMY2, OGT_SULIN  ;  C3N9B4, OGT_SULIY  ;
DR   Q97VW7, OGT_SULSO  ;  Q973C7, OGT_SULTO  ;  C5A3L5, OGT_THEGJ  ;
DR   C6A382, OGT_THESM  ;
//
ID   2.1.1.64
DE   3-demethylubiquinol 3-O-methyltransferase.
CA   S-adenosyl-L-methionine + 3-demethylubiquinone-n = S-adenosyl-L-
CA   homocysteine + ubiquinone-n.
CC   -!- This enzyme is involved in ubiquinone biosynthesis.
CC   -!- Ubiquinones from different organisms have a different number of
CC       prenyl units (for example, ubiquinone-6 in Saccharomyces, ubiquinone-
CC       9 in rat and ubiquinone-10 in human), and thus the natural substrate
CC       for the enzymes from different organisms has a different number of
CC       prenyl units.
CC   -!- However, the enzyme usually shows a low degree of specificity
CC       regarding the number of prenyl units.
CC   -!- For example, the human COQ3 enzyme can restore biosynthesis of
CC       ubiquinone-6 in coq3 deletion mutants of yeast.
CC   -!- The enzymes from yeast, Escherichia coli and rat also catalyze the
CC       methylation of 3,4-dihydroxy-5-all-trans-polyprenylbenzoate (a
CC       reaction that is classified as EC 2.1.1.114).
DR   O49354, COQ3_ARATH ;  Q3T131, COQ3_BOVIN ;  O93995, COQ3_CANAL ;
DR   Q54XD0, COQ3_DICDI ;  Q9NZJ6, COQ3_HUMAN ;  Q8BMS4, COQ3_MOUSE ;
DR   Q63159, COQ3_RAT   ;  O74421, COQ3_SCHPO ;  P27680, COQ3_YEAST ;
DR   A1TSA0, UBIG_ACIAC ;  Q6FFY1, UBIG_ACIAD ;  B7H2Y9, UBIG_ACIB3 ;
DR   B7IBN2, UBIG_ACIB5 ;  B2I023, UBIG_ACIBC ;  B0VMN8, UBIG_ACIBS ;
DR   B0V5X4, UBIG_ACIBY ;  A3MZ07, UBIG_ACTP2 ;  B3H0C8, UBIG_ACTP7 ;
DR   A4SM99, UBIG_AERS4 ;  B9JB78, UBIG_AGRRK ;  Q8UA66, UBIG_AGRT5 ;
DR   Q0AA73, UBIG_ALHEH ;  Q5P7U3, UBIG_AROAE ;  A8HVC4, UBIG_AZOC5 ;
DR   A1K8Q1, UBIG_AZOSB ;  C1DRQ3, UBIG_AZOVD ;  A1URT5, UBIG_BARBK ;
DR   Q6G5K3, UBIG_BARHE ;  Q6G0I1, UBIG_BARQU ;  A9IQF4, UBIG_BART1 ;
DR   Q2L2T5, UBIG_BORA1 ;  Q7WGT9, UBIG_BORBR ;  Q7W5Z6, UBIG_BORPA ;
DR   Q7VZG7, UBIG_BORPE ;  Q89XU2, UBIG_BRAJA ;  A4YKT6, UBIG_BRASO ;
DR   B2S828, UBIG_BRUA1 ;  Q2YLN5, UBIG_BRUA2 ;  A9M8K8, UBIG_BRUC2 ;
DR   C0RFB8, UBIG_BRUMB ;  Q8YJ98, UBIG_BRUME ;  A5VSK3, UBIG_BRUO2 ;
DR   B0CIC6, UBIG_BRUSI ;  Q8FYK0, UBIG_BRUSU ;  B1YV26, UBIG_BURA4 ;
DR   Q1BY35, UBIG_BURCA ;  B1JXR2, UBIG_BURCC ;  A0K5L4, UBIG_BURCH ;
DR   B4EB49, UBIG_BURCJ ;  Q0BHA0, UBIG_BURCM ;  A9ADW3, UBIG_BURM1 ;
DR   Q62M18, UBIG_BURMA ;  Q3JPX1, UBIG_BURP1 ;  B2JEZ6, UBIG_BURP8 ;
DR   B2T641, UBIG_BURPP ;  Q63RZ8, UBIG_BURPS ;  Q39IG8, UBIG_BURS3 ;
DR   Q2SY32, UBIG_BURTA ;  A4JCG7, UBIG_BURVG ;  Q13VB4, UBIG_BURXL ;
DR   B8H209, UBIG_CAUCN ;  Q9A9X1, UBIG_CAUCR ;  B0SW81, UBIG_CAUSK ;
DR   Q7NZ91, UBIG_CHRVO ;  A8ADY5, UBIG_CITK8 ;  Q482G8, UBIG_COLP3 ;
DR   B6J5Y2, UBIG_COXB1 ;  B6J1W2, UBIG_COXB2 ;  A9KGL7, UBIG_COXBN ;
DR   A9NBI0, UBIG_COXBR ;  Q820B5, UBIG_COXBU ;  Q46Y42, UBIG_CUPPJ ;
DR   Q47GP8, UBIG_DECAR ;  A8LQ43, UBIG_DINSH ;  A7ZP50, UBIG_ECO24 ;
DR   B7UFP4, UBIG_ECO27 ;  B7MFZ8, UBIG_ECO45 ;  B7LAP9, UBIG_ECO55 ;
DR   Q8XE29, UBIG_ECO57 ;  B5YX17, UBIG_ECO5E ;  B7NN47, UBIG_ECO7I ;
DR   B7MXR3, UBIG_ECO81 ;  B7M5R7, UBIG_ECO8A ;  C4ZU73, UBIG_ECOBW ;
DR   B1X8C6, UBIG_ECODH ;  A8A296, UBIG_ECOHS ;  Q0TFL0, UBIG_ECOL5 ;
DR   Q8FFP0, UBIG_ECOL6 ;  B1IXV6, UBIG_ECOLC ;  P17993, UBIG_ECOLI ;
DR   B7N5J4, UBIG_ECOLU ;  B6I7I7, UBIG_ECOSE ;  B1LLI3, UBIG_ECOSM ;
DR   Q1R9I4, UBIG_ECOUT ;  A4WCN5, UBIG_ENT38 ;  A7MPA9, UBIG_ENTS8 ;
DR   Q6D7X5, UBIG_ERWCT ;  B2VIL6, UBIG_ERWT9 ;  B7LM95, UBIG_ESCF3 ;
DR   Q7VKW2, UBIG_HAEDU ;  B8F4B1, UBIG_HAEPS ;  Q0I3Y4, UBIG_HAES1 ;
DR   B0UUV6, UBIG_HAES2 ;  Q2SE61, UBIG_HAHCH ;  Q5QZ53, UBIG_IDILO ;
DR   Q28VP7, UBIG_JANSC ;  B5XNZ3, UBIG_KLEP3 ;  A6TBT7, UBIG_KLEP7 ;
DR   B1Y2L3, UBIG_LEPCP ;  Q2W6W0, UBIG_MAGSA ;  A1U3K1, UBIG_MARAV ;
DR   Q0AME1, UBIG_MARMM ;  Q11E01, UBIG_MESSB ;  Q609G2, UBIG_METCA ;
DR   B8IUB0, UBIG_METNO ;  B0UAV0, UBIG_METS4 ;  B8EI29, UBIG_METSB ;
DR   A9M0C4, UBIG_NEIM0 ;  Q9JWE6, UBIG_NEIMA ;  Q9JXI7, UBIG_NEIMB ;
DR   Q81ZZ2, UBIG_NITEU ;  Q2Y6Z3, UBIG_NITMU ;  Q3J8U2, UBIG_NITOC ;
DR   Q3SVP3, UBIG_NITWN ;  A6WXQ0, UBIG_OCHA4 ;  A7HTX8, UBIG_PARL1 ;
DR   Q9CMI6, UBIG_PASMU ;  C6DBN5, UBIG_PECCP ;  Q4FNA2, UBIG_PELUB ;
DR   Q7N2M5, UBIG_PHOLL ;  Q6LPD7, UBIG_PHOPR ;  B4EZ30, UBIG_PROMH ;
DR   Q48FM4, UBIG_PSE14 ;  A6V2Q4, UBIG_PSEA7 ;  B7V9J5, UBIG_PSEA8 ;
DR   Q02PX7, UBIG_PSEAB ;  Q9HZ63, UBIG_PSEAE ;  Q1IDA6, UBIG_PSEE4 ;
DR   Q4K8M4, UBIG_PSEF5 ;  C3K6J1, UBIG_PSEFS ;  Q3ILA5, UBIG_PSEHT ;
DR   A5W7G3, UBIG_PSEP1 ;  Q3K8T6, UBIG_PSEPF ;  B0KTX4, UBIG_PSEPG ;
DR   Q88M10, UBIG_PSEPK ;  B1J5G4, UBIG_PSEPW ;  Q885T9, UBIG_PSESM ;
DR   Q4ZQ90, UBIG_PSEU2 ;  A4VLX7, UBIG_PSEU5 ;  Q4FVG3, UBIG_PSYA2 ;
DR   Q1QEI9, UBIG_PSYCK ;  Q8Y0Z5, UBIG_RALSO ;  B3PP83, UBIG_RHIE6 ;
DR   Q2K3S8, UBIG_RHIEC ;  Q1MBA9, UBIG_RHIL3 ;  Q98G87, UBIG_RHILO ;
DR   B5ZRR7, UBIG_RHILW ;  Q92MK1, UBIG_RHIME ;  C3MHQ9, UBIG_RHISN ;
DR   Q21UL3, UBIG_RHOFD ;  Q2J419, UBIG_RHOP2 ;  Q07VB6, UBIG_RHOP5 ;
DR   Q6NC69, UBIG_RHOPA ;  Q21BZ6, UBIG_RHOPB ;  Q13EZ9, UBIG_RHOPS ;
DR   B3QCF3, UBIG_RHOPT ;  Q2RWE9, UBIG_RHORT ;  A3PNM3, UBIG_RHOS1 ;
DR   Q3IYM5, UBIG_RHOS4 ;  A4WW91, UBIG_RHOS5 ;  B9KPP7, UBIG_RHOSK ;
DR   A8GPB1, UBIG_RICAH ;  A8GX11, UBIG_RICB8 ;  Q1RJC7, UBIG_RICBR ;
DR   A8EY40, UBIG_RICCK ;  Q92H07, UBIG_RICCN ;  Q4UME7, UBIG_RICFE ;
DR   Q9ZCT9, UBIG_RICPR ;  Q68WB5, UBIG_RICTY ;  Q16D32, UBIG_ROSDO ;
DR   Q21IR9, UBIG_SACD2 ;  B5EYW1, UBIG_SALA4 ;  A9MJY3, UBIG_SALAR ;
DR   Q57M77, UBIG_SALCH ;  B5FNR7, UBIG_SALDC ;  B5R249, UBIG_SALEP ;
DR   B5RCA1, UBIG_SALG2 ;  B4TBE3, UBIG_SALHS ;  B4SYU8, UBIG_SALNS ;
DR   Q5PCY1, UBIG_SALPA ;  C0Q093, UBIG_SALPC ;  B5BCS0, UBIG_SALPK ;
DR   B4TPG0, UBIG_SALSV ;  Q8Z560, UBIG_SALTI ;  P37431, UBIG_SALTY ;
DR   A8GGX8, UBIG_SERP5 ;  A1S6C9, UBIG_SHEAM ;  B8EA88, UBIG_SHEB2 ;
DR   A3D499, UBIG_SHEB5 ;  A6WNN7, UBIG_SHEB8 ;  A9L2Y4, UBIG_SHEB9 ;
DR   B0TT38, UBIG_SHEHH ;  Q8EEG9, UBIG_SHEON ;  A8H499, UBIG_SHEPA ;
DR   A4Y759, UBIG_SHEPC ;  A0KWN3, UBIG_SHESA ;  Q0HIX5, UBIG_SHESM ;
DR   Q0HV07, UBIG_SHESR ;  A1RJD1, UBIG_SHESW ;  B2TW20, UBIG_SHIB3 ;
DR   Q31Z65, UBIG_SHIBS ;  Q32DV8, UBIG_SHIDS ;  Q0T2P9, UBIG_SHIF8 ;
DR   Q820C5, UBIG_SHIFL ;  Q3YZX6, UBIG_SHISS ;  Q5LWM6, UBIG_SILPO ;
DR   Q1GCH8, UBIG_SILST ;  A6UCF6, UBIG_SINMW ;  Q2NSL7, UBIG_SODGM ;
DR   Q31GD8, UBIG_THICR ;  Q3SK91, UBIG_THIDA ;  A5F1U0, UBIG_VIBC3 ;
DR   Q9KSJ9, UBIG_VIBCH ;  C3LLV3, UBIG_VIBCM ;  Q5E5J8, UBIG_VIBF1 ;
DR   B5FDT8, UBIG_VIBFM ;  A7MU79, UBIG_VIBHB ;  Q87ND5, UBIG_VIBPA ;
DR   B7VGS0, UBIG_VIBSL ;  Q8D8E0, UBIG_VIBVU ;  Q7MM27, UBIG_VIBVY ;
DR   Q8PK00, UBIG_XANAC ;  Q3BSF8, UBIG_XANC5 ;  Q4UVL4, UBIG_XANC8 ;
DR   B0RS27, UBIG_XANCB ;  Q8P8H2, UBIG_XANCP ;  Q2P2C4, UBIG_XANOM ;
DR   B2SHS9, UBIG_XANOP ;  Q5GZB5, UBIG_XANOR ;  B2I705, UBIG_XYLF2 ;
DR   Q9PAM5, UBIG_XYLFA ;  B0U3W1, UBIG_XYLFM ;  Q87BG5, UBIG_XYLFT ;
DR   A1JLA0, UBIG_YERE8 ;  A7FKF4, UBIG_YERP3 ;  Q1C9H5, UBIG_YERPA ;
DR   B2K9A4, UBIG_YERPB ;  Q8ZGR6, UBIG_YERPE ;  A9R284, UBIG_YERPG ;
DR   Q1CFZ1, UBIG_YERPN ;  A4TNI8, UBIG_YERPP ;  Q66CZ4, UBIG_YERPS ;
DR   B1JS96, UBIG_YERPY ;
//
ID   2.1.1.65
DE   Licodione 2'-O-methyltransferase.
CA   S-adenosyl-L-methionine + licodione = S-adenosyl-L-homocysteine + 2'-O-
CA   methyllicodione.
CC   -!- As well as licodione (1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-
CC       1,3-propanedione), the 2''-hydroxy-derivative and isoliquiritigenin
CC       can act as acceptors, more slowly.
//
ID   2.1.1.66
DE   rRNA (adenosine-2'-O-)-methyltransferase.
AN   RNA-pentose methylase.
AN   Thiostrepton-resistance methylase.
CA   S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA
CA   containing a single residue of 2'-O-methyladenosine.
DR   P18644, TSNR_STRCN ;  P52393, TSNR_STRLU ;
//
ID   2.1.1.67
DE   Thiopurine S-methyltransferase.
CA   S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine +
CA   a thiopurine S-methylether.
CC   -!- Also acts, more slowly, on thiopyrimidines and aromatic thiols.
CC   -!- Not identical with EC 2.1.1.9.
DR   Q6F8H8, TPMT_ACIAD ;  B6ENK8, TPMT_ALISL ;  C1DRL5, TPMT_AZOVD ;
DR   Q2KV81, TPMT_BORA1 ;  Q7WM36, TPMT_BORBR ;  Q7W8H4, TPMT_BORPA ;
DR   A9I3K3, TPMT_BORPD ;  Q7VZM5, TPMT_BORPE ;  Q17QQ2, TPMT_BOVIN ;
DR   Q8HX86, TPMT_CANFA ;  Q3BCR4, TPMT_CHLAE ;  Q504A5, TPMT_DANRE ;
DR   Q6EIC1, TPMT_FELCA ;  Q14FX6, TPMT_FRAT1 ;  A0Q3W9, TPMT_FRATN ;
DR   Q5NEH3, TPMT_FRATT ;  Q5FT39, TPMT_GLUOX ;  Q3BCR3, TPMT_GORGO ;
DR   Q3BCR6, TPMT_HORSE ;  P51580, TPMT_HUMAN ;  Q5X154, TPMT_LEGPA ;
DR   A5II06, TPMT_LEGPC ;  Q5ZRP5, TPMT_LEGPH ;  Q5WSX9, TPMT_LEGPL ;
DR   Q3BCR5, TPMT_LYCPI ;  Q3BCR9, TPMT_LYNRU ;  A1U560, TPMT_MARAV ;
DR   Q60AQ2, TPMT_METCA ;  O55060, TPMT_MOUSE ;  Q9QX22, TPMT_MUSSP ;
DR   Q0ADU3, TPMT_NITEC ;  Q2Y6S0, TPMT_NITMU ;  Q3BCR0, TPMT_PANLE ;
DR   Q3BCR1, TPMT_PANPR ;  Q3BCR2, TPMT_PANTI ;  Q3BCR8, TPMT_PANTR ;
DR   Q6LRI5, TPMT_PHOPR ;  Q5RBJ3, TPMT_PONPY ;  A6V3Q8, TPMT_PSEA7 ;
DR   B7VAP9, TPMT_PSEA8 ;  Q02NZ5, TPMT_PSEAB ;  Q9I011, TPMT_PSEAE ;
DR   Q1ID19, TPMT_PSEE4 ;  Q4K8U2, TPMT_PSEF5 ;  C3K732, TPMT_PSEFS ;
DR   A4XVB5, TPMT_PSEMY ;  A5W759, TPMT_PSEP1 ;  Q3K932, TPMT_PSEPF ;
DR   B0KUP7, TPMT_PSEPG ;  Q88LQ9, TPMT_PSEPK ;  B1J4W2, TPMT_PSEPW ;
DR   O86262, TPMT_PSESJ ;  Q885Q4, TPMT_PSESM ;  Q4ZQC3, TPMT_PSEU2 ;
DR   Q93JT2, TPMT_PSEU5 ;  Q1Q8I2, TPMT_PSYCK ;  Q3BCQ8, TPMT_RABIT ;
DR   Q9Z0T0, TPMT_RAT   ;  A1S2Z7, TPMT_SHEAM ;  B8ECC0, TPMT_SHEB2 ;
DR   A3D007, TPMT_SHEB5 ;  A6WSW9, TPMT_SHEB8 ;  A9L3X6, TPMT_SHEB9 ;
DR   Q12RU3, TPMT_SHEDO ;  Q07XD8, TPMT_SHEFN ;  B0TSS5, TPMT_SHEHH ;
DR   A3QI29, TPMT_SHELP ;  Q8EJ86, TPMT_SHEON ;  A8H029, TPMT_SHEPA ;
DR   A4YAM5, TPMT_SHEPC ;  B8CUG6, TPMT_SHEPW ;  A0KSQ0, TPMT_SHESA ;
DR   A8G0J1, TPMT_SHESH ;  Q0HMQ6, TPMT_SHESM ;  Q0HR25, TPMT_SHESR ;
DR   A1RFQ1, TPMT_SHESW ;  B1KHT1, TPMT_SHEWM ;  C5BIS1, TPMT_TERTT ;
DR   A5F1V4, TPMT_VIBC3 ;  Q9KSN0, TPMT_VIBCH ;  C3LLS2, TPMT_VIBCM ;
DR   Q5E4N9, TPMT_VIBF1 ;  B5FEQ9, TPMT_VIBFM ;  A7MVH9, TPMT_VIBHB ;
DR   Q87Q54, TPMT_VIBPA ;  B7VPF3, TPMT_VIBSL ;  Q8DA33, TPMT_VIBVU ;
DR   Q7MK46, TPMT_VIBVY ;  Q8PMI8, TPMT_XANAC ;  Q3BVI6, TPMT_XANC5 ;
DR   Q4UST1, TPMT_XANC8 ;  Q8PAT3, TPMT_XANCP ;  A7IIX3, TPMT_XANP2 ;
DR   Q6C6X6, TPMT_YARLI ;
//
ID   2.1.1.68
DE   Caffeate O-methyltransferase.
CA   S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-
CA   homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate.
CC   -!- 3,4-dihydroxybenzaldehyde and catechol can act as acceptor, more
CC       slowly.
DR   Q6T1F5, COMT1_AMMMJ;  Q9FQY8, COMT1_CAPAN;  O81646, COMT1_CAPCH;
DR   Q8W013, COMT1_CATRO;  O23760, COMT1_CLABR;  Q8LL87, COMT1_COFCA;
DR   Q9SWC2, COMT1_EUCGL;  P46484, COMT1_EUCGU;  Q06509, COMT1_MAIZE;
DR   P28002, COMT1_MEDSA;  Q9XGW0, COMT1_OCIBA;  Q43046, COMT1_POPKI;
DR   Q00763, COMT1_POPTM;  Q43609, COMT1_PRUDU;  Q8GU25, COMT1_ROSCH;
DR   O82054, COMT1_SACOF;  Q43239, COMT1_ZINEL;  Q9XGV9, COMT2_OCIBA;
DR   Q41086, COMT2_POPTM;  Q43047, COMT3_POPKI;
//
ID   2.1.1.69
DE   5-hydroxyfuranocoumarin 5-O-methyltransferase.
AN   Bergaptol 5-O-methyltransferase.
AN   Bergaptol methyltransferase.
AN   Bergaptol O-methyltransferase.
AN   BMT.
AN   Furanocoumarin 5-methyltransferase.
AN   Furanocoumarin 5-O-methyltransferase.
CA   (1) S-adenosyl-L-methionine + a 5-hydroxyfurocoumarin = S-adenosyl-L-
CA   homocysteine + a 5-methoxyfurocoumarin.
CA   (2) S-adenosyl-L-methionine + bergaptol = S-adenosyl-L-homocysteine +
CA   bergapten.
CC   -!- Converts bergaptol into bergapten, which has therapeutic potential in
CC       the treatment of psoriasis as it has photosensitizing and
CC       antiproliferative activities.
CC   -!- Methylates the 5-hydroxy group of some hydroxy- and methylcoumarins,
CC       such as 5-hydroxyxanthotoxin, but has little activity on non-coumarin
CC       phenols; caffeate, 5-hydroxyferulate and daphnetin are not
CC       substrates.
CC   -!- Cu(2+), Zn(2+) and Co(2+) cause enzyme inhibition.
CC   -!- See also EC 2.1.1.70.
CC   -!- Formerly EC 2.1.1.92.
DR   Q6T1F6, BMT_AMMMJ  ;  A8J6X1, BMT_GLELI  ;
//
ID   2.1.1.70
DE   8-hydroxyfuranocoumarin 8-O-methyltransferase.
AN   Furanocoumarin 8-methyltransferase.
AN   Furanocoumarin 8-O-methyl-transferase.
AN   Xanthotoxol 8-O-methyltransferase.
AN   XMT.
CA   (1) S-adenosyl-L-methionine + an 8-hydroxyfurocoumarin = S-adenosyl-L-
CA   homocysteine + an 8-methoxyfurocoumarin.
CA   (2) S-adenosyl-L-methionine + xanthotoxol = S-adenosyl-L-homocysteine +
CA   xanthotoxin.
CC   -!- Converts xanthotoxol into xanthotoxin, which has therapeutic
CC       potential in the treatment of psoriasis as it has photosensitizing
CC       and antiproliferative activities.
CC   -!- Methylates the 8-hydroxy group of some hydroxy- and methylcoumarins,
CC       but has little activity on non-coumarin phenols.
CC   -!- See also EC 2.1.1.69.
CC   -!- Formerly EC 2.1.1.93.
//
ID   2.1.1.71
DE   Phosphatidyl-N-methylethanolamine N-methyltransferase.
CA   S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine = S-adenosyl-
CA   L-homocysteine + phosphatidyl-N-dimethylethanolamine.
CC   -!- Also catalyzes the transfer of a further methylgroup, producing
CC       phosphatidylcholine.
//
ID   2.1.1.72
DE   Site-specific DNA-methyltransferase (adenine-specific).
AN   Modification methylase.
AN   N-6 adenine-specific DNA methylase.
AN   Restriction-modification system.
CA   S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine +
CA   DNA 6-methylaminopurine.
CC   -!- This is a large group of enzymes, the majority of which, with enzymes
CC       of similar site specificity listed as EC 3.1.21.3, EC 3.1.21.4 and
CC       EC 3.1.21.5, form so-called restriction-modification systems.
CC   -!- See the REBASE database for a complete list of these enzymes:
CC       http://rebase.neb.com/rebase/
PR   PROSITE; PDOC00087;
DR   P21311, DMA7_ECOLX ;  P12427, DMA_BPT2   ;  P04392, DMA_BPT4   ;
DR   P0AEE9, DMA_ECO57  ;  P0AEE8, DMA_ECOLI  ;  P44431, DMA_HAEIN  ;
DR   P0A292, DMA_SALTI  ;  P0A291, DMA_SALTY  ;  P45454, DMA_SERMA  ;
DR   O33844, DMA_TREPA  ;  A5F520, DMA_VIBC3  ;  P0C6Q8, DMA_VIBCH  ;
DR   P34720, MT1A_MORBO ;  P34721, MT1B_MORBO ;  P25240, MT57_ECOLX ;
DR   P25201, MTA1_ACICA ;  P58284, MTA1_AZOBR ;  B2S9Y5, MTB1_BRUA1 ;
DR   Q2YMK2, MTB1_BRUA2 ;  P0C116, MTB1_BRUAB ;  A9M916, MTB1_BRUC2 ;
DR   Q8YFS6, MTB1_BRUME ;  A5VP58, MTB1_BRUO2 ;  B0CKH7, MTB1_BRUSI ;
DR   Q8G242, MTB1_BRUSU ;  A6WWI2, MTB1_OCHA4 ;  P22772, MTB3_BACAR ;
DR   P33563, MTBB_BACSU ;  B8GZ33, MTC1_CAUCN ;  P0CAW2, MTC1_CAUCR ;
DR   P42828, MTC1_COREQ ;  P43423, MTC1_GEOSE ;  Q01511, MTC1_PBCVC ;
DR   P31118, MTC2_PBCV1 ;  P10835, MTC3_PBCVC ;  P04043, MTD21_STRPN;
DR   P09358, MTD22_STRPN;  P00472, MTE1_ECOLX ;  P04393, MTE5_ECOLX ;
DR   P14827, MTEC_ENTCL ;  P14871, MTF1_PLAOK ;  P20590, MTH1_HAEIF ;
DR   P29538, MTH1_HAEPA ;  P00473, MTH2_HAEPH ;  P43871, MTH3_HAEIN ;
DR   P50193, MTHB_HAEPH ;  P17744, MTHC_HAEIF ;  P44414, MTHD_HAEIN ;
DR   P25238, MTK1_KLEPN ;  P35516, MTL1_LACLA ;  P50179, MTL21_LACLC;
DR   P50178, MTL22_LACLC;  P50190, MTM1_MICAM ;  P23192, MTM2_MORBO ;
DR   Q58015, MTM3_METJA ;  P43641, MTMU_MYCSP ;  P24582, MTN3_NEILA ;
DR   P05103, MTP7_PSEAE ;  P00474, MTPS_PROST ;  P52284, MTR1_PBCVX ;
DR   P14751, MTR1_RHOSH ;  O30569, MTS1_RHIME ;  Q53609, MTS1_STRAL ;
DR   P29347, MTS1_STRSA ;  P29749, MTT8_THET8 ;  P14385, MTTA_THEAQ ;
DR   P43422, MTV1_GEOSE ;  Q03055, MTV1_VIBS3 ;  P96188, MTX1_XANCR ;
DR   Q9KVZ8, MTX1_XANVA ;  P10484, T1M1_ECOLX ;  P75436, T1MD_MYCPN ;
DR   Q47282, T1ME_ECOLX ;  Q57168, T1MH_HAEIN ;  Q60297, T1MH_METJA ;
DR   P08957, T1MK_ECOLI ;  Q47163, T1MP_ECOLX ;  Q89Z59, T1M_BACTN  ;
DR   P07989, T1M_SALPO  ;  P40813, T1M_SALTY  ;  P25239, T257_ECOLX ;
DR   P71366, T3MH_HAEIN ;  P08763, T3MO_BPP1  ;  P12364, T3MO_ECOLX ;
DR   P40814, T3MO_SALTY ;  Q07605, T4BA_BACCO ;  P75561, Y108_MYCPN ;
DR   P75451, Y111_MYCPN ;  P45106, Y1201_HAEIN;  Q58617, Y1220_METJA;
DR   Q9PDL1, Y1368_XYLFA;  Q9JYC0, Y1655_NEIMB;  Q9I347, Y1678_PSEAE;
DR   Q49400, Y184_MYCGE ;  Q9JTA1, Y1912_NEIMA;  Q50290, Y198_MYCPN ;
DR   Q9KQ83, Y2118_VIBCH;  Q60301, Y3402_METJA;  Q9CNN7, Y390_PASMU ;
DR   Q87DS5, Y606_XYLFT ;  P39199, YFCB_ECOLI ;  P0A294, YFCB_SALTI ;
DR   P0A293, YFCB_SALTY ;  P39200, YFCB_VIBAN ;  P28638, YHDJ_ECOLI ;
DR   P51715, YO13_BPHP1 ;
//
ID   2.1.1.73
DE   Transferred entry: 2.1.1.37.
//
ID   2.1.1.74
DE   Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase (FADH(2)-
DE   oxidizing).
AN   Folate-dependent ribothymidyl synthase.
CA   5,10-methylenetetrahydrofolate + tRNA containing uridine at position 54 +
CA   FADH(2) = tetrahydrofolate + tRNA containing ribothymidine at position 54
CA   + FAD.
CC   -!- Up to 25% of the bases in mature tRNA are post-translationally
CC       modified or hypermodified.
CC   -!- One almost universal post-translational modification is the
CC       conversion of U(54) (in the T-Psi-C loop) into ribothymidine
CC       (5-methyluridine), and this modification is found in most species
CC       studied to date.
CC   -!- Unlike this enzyme, which uses 5,10-methylenetetrahydrofolate and
CC       FADH(2) to supply the atoms for methylation of U(54), EC 2.1.1.35
CC       uses S-adenosyl-L-methionine.
CC   -!- Formerly EC 2.1.2.12.
DR   Q6F1M4, TMFO1_MESFL;  Q2SS13, TMFO1_MYCCT;  Q6MTM6, TMFO1_MYCMS;
DR   Q6F0T3, TMFO2_MESFL;  Q2SRN2, TMFO2_MYCCT;  Q6MTB4, TMFO2_MYCMS;
DR   B0C6V8, TRMFO_ACAM1;  A9NHD0, TRMFO_ACHLI;  Q1IHM1, TRMFO_ACIBL;
DR   Q8UET6, TRMFO_AGRT5;  B8JES4, TRMFO_ANAD2;  Q2ILE0, TRMFO_ANADE;
DR   A7HDU6, TRMFO_ANADF;  B4UII2, TRMFO_ANASK;  B9MM32, TRMFO_ANATD;
DR   Q3MA89, TRMFO_ANAVT;  B7GGC8, TRMFO_ANOFW;  O66913, TRMFO_AQUAE;
DR   A8ID68, TRMFO_AZOC5;  A7Z4N3, TRMFO_BACA2;  C3P5N4, TRMFO_BACAA;
DR   C3L795, TRMFO_BACAC;  A0RHK5, TRMFO_BACAH;  Q81WK3, TRMFO_BACAN;
DR   B7JJB0, TRMFO_BACC0;  Q732N8, TRMFO_BACC1;  B7IUJ1, TRMFO_BACC2;
DR   C1EP56, TRMFO_BACC3;  B7HDV5, TRMFO_BACC4;  B7HLG5, TRMFO_BACC7;
DR   A7GRG2, TRMFO_BACCN;  B9IVC1, TRMFO_BACCQ;  Q819X4, TRMFO_BACCR;
DR   Q636J4, TRMFO_BACCZ;  Q9KA24, TRMFO_BACHD;  Q6HEY3, TRMFO_BACHK;
DR   Q65JN6, TRMFO_BACLD;  A8FD77, TRMFO_BACP2;  Q5WFP8, TRMFO_BACSK;
DR   P39815, TRMFO_BACSU;  A9VT70, TRMFO_BACWK;  A1USB2, TRMFO_BARBK;
DR   Q6G3Y9, TRMFO_BARHE;  A9ISB8, TRMFO_BART1;  Q6MHW5, TRMFO_BDEBA;
DR   B2IGU6, TRMFO_BEII9;  Q89L21, TRMFO_BRAJA;  A5EJU4, TRMFO_BRASB;
DR   A4YV54, TRMFO_BRASO;  C0ZFA9, TRMFO_BREBN;  Q2YNL7, TRMFO_BRUA2;
DR   Q57DL3, TRMFO_BRUAB;  A9MAR7, TRMFO_BRUC2;  P64232, TRMFO_BRUME;
DR   A5VQ76, TRMFO_BRUO2;  B0CLM0, TRMFO_BRUSI;  P64233, TRMFO_BRUSU;
DR   A4XIW8, TRMFO_CALS8;  Q3AB71, TRMFO_CARHZ;  Q9A566, TRMFO_CAUCR;
DR   B0T866, TRMFO_CAUSK;  A3DCM0, TRMFO_CLOTH;  B5Y8G1, TRMFO_COPPD;
DR   B1WR77, TRMFO_CYAA5;  Q1J148, TRMFO_DEIGD;  Q9RXU7, TRMFO_DEIRA;
DR   B1I258, TRMFO_DESAP;  Q312C5, TRMFO_DESDG;  Q24UF0, TRMFO_DESHY;
DR   Q6ALS7, TRMFO_DESPS;  A4J5Z8, TRMFO_DESRM;  Q729K0, TRMFO_DESVH;
DR   A1VBW6, TRMFO_DESVV;  B5YFC6, TRMFO_DICT6;  B8E2F5, TRMFO_DICTD;
DR   A8LK18, TRMFO_DINSH;  Q834K1, TRMFO_ENTFA;  Q2NAC8, TRMFO_ERYLH;
DR   B1YIB2, TRMFO_EXIS2;  C4L614, TRMFO_EXISA;  A7HL16, TRMFO_FERNB;
DR   Q8REM9, TRMFO_FUSNN;  B5EHR5, TRMFO_GEOBB;  Q39X89, TRMFO_GEOMG;
DR   B9M5T8, TRMFO_GEOSF;  Q74A44, TRMFO_GEOSL;  C6E557, TRMFO_GEOSM;
DR   A5G7S3, TRMFO_GEOUR;  Q7NFC3, TRMFO_GLOVI;  B0TH93, TRMFO_HELMI;
DR   B4U7L4, TRMFO_HYDS0;  Q0BYJ6, TRMFO_HYPNA;  Q28PE7, TRMFO_JANSC;
DR   Q5FKE1, TRMFO_LACAC;  Q039E2, TRMFO_LACC3;  Q1G9V1, TRMFO_LACDA;
DR   Q04A02, TRMFO_LACDB;  Q043R6, TRMFO_LACGA;  A8YV48, TRMFO_LACH4;
DR   Q74JJ8, TRMFO_LACJO;  Q9CG79, TRMFO_LACLA;  A2RKQ0, TRMFO_LACLM;
DR   Q02YZ3, TRMFO_LACLS;  Q88W23, TRMFO_LACPL;  Q1WU04, TRMFO_LACS1;
DR   Q38WZ1, TRMFO_LACSS;  Q1MQ25, TRMFO_LAWIP;  Q92C76, TRMFO_LISIN;
DR   Q720E5, TRMFO_LISMF;  Q8Y7K1, TRMFO_LISMO;  A0AI79, TRMFO_LISW6;
DR   B1HQJ3, TRMFO_LYSSC;  Q2W4D9, TRMFO_MAGSA;  A0LDC6, TRMFO_MAGSM;
DR   Q0ANF3, TRMFO_MARMM;  Q11HD9, TRMFO_MESSB;  A9VXT4, TRMFO_METEP;
DR   B1ZES7, TRMFO_METPB;  B1M5H7, TRMFO_METRJ;  B0UI96, TRMFO_METS4;
DR   B0JFX8, TRMFO_MICAN;  Q2RJP8, TRMFO_MOOTA;  A5IXT6, TRMFO_MYCAP;
DR   Q9S449, TRMFO_MYXXD;  B2A334, TRMFO_NATTJ;  Q1QMC9, TRMFO_NITHX;
DR   Q3SRR6, TRMFO_NITWN;  Q8YNJ4, TRMFO_NOSS1;  Q2G718, TRMFO_NOVAD;
DR   A6X1E3, TRMFO_OCHA4;  A1B9F0, TRMFO_PARDP;  A7HXL5, TRMFO_PARL1;
DR   Q3A7H9, TRMFO_PELCD;  A1ALD8, TRMFO_PELPD;  A5D2W5, TRMFO_PELTS;
DR   C0QTE2, TRMFO_PERMH;  B4RDH0, TRMFO_PHEZH;  A3PDM1, TRMFO_PROM0;
DR   A2C3G4, TRMFO_PROM1;  A8G5I6, TRMFO_PROM2;  A2C8E1, TRMFO_PROM3;
DR   A9BEK6, TRMFO_PROM4;  A2BXA3, TRMFO_PROM5;  Q31AA9, TRMFO_PROM9;
DR   Q7VD04, TRMFO_PROMA;  Q7TUW5, TRMFO_PROMM;  Q7TU75, TRMFO_PROMP;
DR   A2BRU5, TRMFO_PROMS;  Q46K52, TRMFO_PROMT;  Q2K957, TRMFO_RHIEC;
DR   Q1MHL2, TRMFO_RHIL3;  Q98LE1, TRMFO_RHILO;  Q92Q15, TRMFO_RHIME;
DR   O68141, TRMFO_RHOCB;  Q2IWI0, TRMFO_RHOP2;  Q07MJ4, TRMFO_RHOP5;
DR   Q6N5Z1, TRMFO_RHOPA;  Q213W6, TRMFO_RHOPB;  Q136I8, TRMFO_RHOPS;
DR   Q2RTI8, TRMFO_RHORT;  A3PJ80, TRMFO_RHOS1;  Q3J349, TRMFO_RHOS4;
DR   A4WRQ2, TRMFO_RHOS5;  B9KRK8, TRMFO_RHOSK;  Q166D3, TRMFO_ROSDO;
DR   Q1ATM0, TRMFO_RUBXD;  Q5LST0, TRMFO_SILPO;  Q1GGU2, TRMFO_SILST;
DR   A6U8P9, TRMFO_SINMW;  Q02C58, TRMFO_SOLUE;  A9FRC1, TRMFO_SORC5;
DR   Q1GTZ7, TRMFO_SPHAL;  A5V4M8, TRMFO_SPHWW;  A7X1M6, TRMFO_STAA1;
DR   A6U169, TRMFO_STAA2;  Q2FHI7, TRMFO_STAA3;  Q2FZ31, TRMFO_STAA8;
DR   A5ISD5, TRMFO_STAA9;  Q2YXL7, TRMFO_STAAB;  Q5HGI1, TRMFO_STAAC;
DR   A6QGF1, TRMFO_STAAE;  P64234, TRMFO_STAAM;  P64235, TRMFO_STAAN;
DR   Q6GHI4, TRMFO_STAAR;  Q6G9W2, TRMFO_STAAS;  A8Z3T1, TRMFO_STAAT;
DR   P64236, TRMFO_STAAW;  B9DPG3, TRMFO_STACT;  Q5HPU1, TRMFO_STAEQ;
DR   Q8CPH2, TRMFO_STAES;  Q4L5V3, TRMFO_STAHJ;  Q49X36, TRMFO_STAS1;
DR   Q3K1B8, TRMFO_STRA1;  Q8E5M6, TRMFO_STRA3;  Q8DZX5, TRMFO_STRA5;
DR   C0M6C7, TRMFO_STRE4;  A8AXH0, TRMFO_STRGC;  P05428, TRMFO_STRMU;
DR   Q99ZL9, TRMFO_STRP1;  Q04KY2, TRMFO_STRP2;  P0DB36, TRMFO_STRP3;
DR   B5E446, TRMFO_STRP4;  Q5XC46, TRMFO_STRP6;  C1C6S2, TRMFO_STRP7;
DR   Q8P106, TRMFO_STRP8;  Q1JBP0, TRMFO_STRPB;  Q1JLM2, TRMFO_STRPC;
DR   Q1JGS2, TRMFO_STRPD;  Q1J6J1, TRMFO_STRPF;  A2REF7, TRMFO_STRPG;
DR   B1IBA6, TRMFO_STRPI;  B8ZP43, TRMFO_STRPJ;  Q48TI1, TRMFO_STRPM;
DR   Q97R84, TRMFO_STRPN;  P0DB37, TRMFO_STRPQ;  B2IP98, TRMFO_STRPS;
DR   Q8DQ51, TRMFO_STRR6;  A4W125, TRMFO_STRS2;  C0MFF9, TRMFO_STRS7;
DR   A3CN32, TRMFO_STRSV;  A4VUS8, TRMFO_STRSY;  Q5M014, TRMFO_STRT1;
DR   Q5M4M7, TRMFO_STRT2;  Q03KX0, TRMFO_STRTD;  B9DS62, TRMFO_STRU0;
DR   C1CDT9, TRMFO_STRZJ;  C1CK27, TRMFO_STRZP;  C1CRV5, TRMFO_STRZT;
DR   B2V9U2, TRMFO_SULSY;  Q67PC6, TRMFO_SYMTH;  Q2LT41, TRMFO_SYNAS;
DR   Q31NM4, TRMFO_SYNE7;  Q2JRF7, TRMFO_SYNJA;  Q2JQ64, TRMFO_SYNJB;
DR   B1XK17, TRMFO_SYNP2;  Q5N5J0, TRMFO_SYNP6;  A5GLJ3, TRMFO_SYNPW;
DR   Q7U7T2, TRMFO_SYNPX;  A5GU85, TRMFO_SYNR3;  Q0IB24, TRMFO_SYNS3;
DR   Q3AX63, TRMFO_SYNS9;  Q3AIZ7, TRMFO_SYNSC;  Q0AYP4, TRMFO_SYNWW;
DR   Q55692, TRMFO_SYNY3;  B7IFU6, TRMFO_THEAB;  P59109, TRMFO_THEEB;
DR   A8F516, TRMFO_THELT;  A6LJK8, TRMFO_THEM4;  Q9WZJ3, TRMFO_THEMA;
DR   B9KAP3, TRMFO_THENN;  A5IJ51, TRMFO_THEP1;  B1L7X2, TRMFO_THESQ;
DR   Q72IQ5, TRMFO_THET2;  Q5SID2, TRMFO_THET8;  A7INE1, TRMFO_XANP2;
DR   Q5NPP5, TRMFO_ZYMMO;
//
ID   2.1.1.75
DE   Apigenin 4'-O-methyltransferase.
AN   Flavonoid O-methyltransferase.
CA   S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone = S-adenosyl-L-
CA   homocysteine + 4'-methoxy-5,7-dihydroxyflavone.
CC   -!- Converts apigenin into acacetin.
CC   -!- Naringenin (5,7,4'-trihydroxyflavonone) can also act as acceptor,
CC       more slowly.
//
ID   2.1.1.76
DE   Quercetin 3-O-methyltransferase.
AN   Flavonol 3-O-methyltransferase.
CA   S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-
CA   homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone.
CC   -!- Specific for quercetin.
CC   -!- Related enzymes bring about the 3-O-methylation of other flavonols,
CC       such as galangin and kaempferol.
DR   Q9FK25, OMT1_ARATH ;  P59049, OMT1_CHRAE ;  Q6ZD89, OMT1_ORYSJ ;
DR   Q42653, OMT2_CHRAE ;
//
ID   2.1.1.77
DE   Protein-L-isoaspartate(D-aspartate) O-methyltransferase.
AN   L-isoaspartyl protein carboxyl methyltransferase.
AN   Protein beta-aspartate O-methyltransferase.
AN   Protein D-aspartate methyltransferase.
AN   Protein L-isoaspartyl methyltransferase.
CA   S-adenosyl-L-methionine + protein L-isoaspartate = S-adenosyl-L-
CA   homocysteine + protein L-isoaspartate alpha-methyl ester.
CC   -!- D-aspartate (but not L-aspartate) residues in proteins can also act
CC       as acceptors.
CC   -!- Formerly EC 2.1.1.24.
PR   PROSITE; PDOC00985;
DR   A7HC32, PIMT1_ANADF;  O30199, PIMT1_ARCFU;  Q0KB67, PIMT1_CUPNH;
DR   A5GEF7, PIMT1_GEOUR;  A1TZ54, PIMT1_MARAV;  Q8TT93, PIMT1_METAC;
DR   Q2YCR1, PIMT1_NITMU;  Q3JCZ3, PIMT1_NITOC;  A1ASL8, PIMT1_PELPD;
DR   Q12A85, PIMT1_POLSJ;  Q2J302, PIMT1_RHOP2;  A8FST4, PIMT1_SHESH;
DR   A0LL58, PIMT1_SYNFM;  A7HHV3, PIMT2_ANADF;  O27962, PIMT2_ARCFU;
DR   Q0K951, PIMT2_CUPNH;  A5G4S7, PIMT2_GEOUR;  A1U4P7, PIMT2_MARAV;
DR   Q8TT94, PIMT2_METAC;  Q2YBR7, PIMT2_NITMU;  Q3JAW6, PIMT2_NITOC;
DR   A1ASW6, PIMT2_PELPD;  Q123X2, PIMT2_POLSJ;  Q2IWH1, PIMT2_RHOP2;
DR   A8FX24, PIMT2_SHESH;  A0LM89, PIMT2_SYNFM;  A5G6S0, PIMT3_GEOUR;
DR   Q1INS6, PIMT_ACIBL ;  A0KGH9, PIMT_AERHH ;  Q9YDA1, PIMT_AERPE ;
DR   A4SRB5, PIMT_AERS4 ;  Q0VQD1, PIMT_ALCBS ;  Q0A7L5, PIMT_ALHEH ;
DR   B6EKL2, PIMT_ALISL ;  B4RZG8, PIMT_ALTMD ;  B8J9E3, PIMT_ANAD2 ;
DR   Q2IIL9, PIMT_ANADE ;  Q42539, PIMT_ARATH ;  Q5P833, PIMT_AROAE ;
DR   A8I4G3, PIMT_AZOC5 ;  A1K4F0, PIMT_AZOSB ;  Q2L008, PIMT_BORA1 ;
DR   Q7WI37, PIMT_BORBR ;  Q7W671, PIMT_BORPA ;  A9IP04, PIMT_BORPD ;
DR   P15246, PIMT_BOVIN ;  A5EJV5, PIMT_BRASB ;  A4YV66, PIMT_BRASO ;
DR   B1YRE4, PIMT_BURA4 ;  Q1BGY4, PIMT_BURCA ;  B1JTA2, PIMT_BURCC ;
DR   A0K7U6, PIMT_BURCH ;  Q0BEV7, PIMT_BURCM ;  A3MK86, PIMT_BURM7 ;
DR   A2S291, PIMT_BURM9 ;  Q62JV3, PIMT_BURMA ;  A1V4L2, PIMT_BURMS ;
DR   A3NVY1, PIMT_BURP0 ;  Q3JRP1, PIMT_BURP1 ;  A3NA64, PIMT_BURP6 ;
DR   B2JG67, PIMT_BURP8 ;  Q63UU3, PIMT_BURPS ;  Q39FP9, PIMT_BURS3 ;
DR   Q2SWF4, PIMT_BURTA ;  A4JEQ0, PIMT_BURVG ;  Q27873, PIMT_CAEEL ;
DR   B8GX51, PIMT_CAUCN ;  Q9A6T6, PIMT_CAUCR ;  B0T1Q1, PIMT_CAUSK ;
DR   B3PJA8, PIMT_CELJU ;  Q5F3N1, PIMT_CHICK ;  B3EEX3, PIMT_CHLL2 ;
DR   B3QQM1, PIMT_CHLP8 ;  B3ELJ9, PIMT_CHLPB ;  A1BDC1, PIMT_CHLPD ;
DR   Q8KFW8, PIMT_CHLTE ;  Q1QU77, PIMT_CHRSD ;  Q7NRV0, PIMT_CHRVO ;
DR   A8ANV7, PIMT_CITK8 ;  Q487E5, PIMT_COLP3 ;  Q46ZH2, PIMT_CUPPJ ;
DR   Q11TS0, PIMT_CYTH3 ;  Q92047, PIMT_DANRE ;  Q47D25, PIMT_DECAR ;
DR   C6BTT9, PIMT_DESAD ;  B8J017, PIMT_DESDA ;  Q30ZM2, PIMT_DESDG ;
DR   A8ZXR8, PIMT_DESOH ;  Q6ARM1, PIMT_DESPS ;  Q72AZ1, PIMT_DESVH ;
DR   B8DJP7, PIMT_DESVM ;  A1VD15, PIMT_DESVV ;  Q9GPS6, PIMT_DICDI ;
DR   B5YF00, PIMT_DICT6 ;  B8E0T1, PIMT_DICTD ;  A8LQK6, PIMT_DINSH ;
DR   Q27869, PIMT_DROME ;  A7ZQI7, PIMT_ECO24 ;  B7UHG2, PIMT_ECO27 ;
DR   B7MKL7, PIMT_ECO45 ;  B7LEG1, PIMT_ECO55 ;  P0A7A6, PIMT_ECO57 ;
DR   B5Z3A5, PIMT_ECO5E ;  B7NT87, PIMT_ECO7I ;  B7MZ44, PIMT_ECO81 ;
DR   B7LXF5, PIMT_ECO8A ;  C4ZZP7, PIMT_ECOBW ;  B1XCR9, PIMT_ECODH ;
DR   A8A3M2, PIMT_ECOHS ;  A1AET7, PIMT_ECOK1 ;  Q8FEJ8, PIMT_ECOL6 ;
DR   B1IUT6, PIMT_ECOLC ;  P0A7A5, PIMT_ECOLI ;  B7N6X3, PIMT_ECOLU ;
DR   B6I6D3, PIMT_ECOSE ;  B1LQ63, PIMT_ECOSM ;  Q1R7U8, PIMT_ECOUT ;
DR   A4WDU8, PIMT_ENT38 ;  A7MJ61, PIMT_ENTS8 ;  Q6D1B6, PIMT_ERWCT ;
DR   B2VG25, PIMT_ERWT9 ;  B7LWJ2, PIMT_ESCF3 ;  A7HL14, PIMT_FERNB ;
DR   A5FEA5, PIMT_FLAJ1 ;  A6H0V1, PIMT_FLAPJ ;  B3E6I4, PIMT_GEOLS ;
DR   Q39VS0, PIMT_GEOMG ;  Q74CZ5, PIMT_GEOSL ;  Q7NJY2, PIMT_GLOVI ;
DR   A0LZ51, PIMT_GRAFK ;  Q2SKW3, PIMT_HAHCH ;  A1WWY5, PIMT_HALHL ;
DR   B6JMT1, PIMT_HELP2 ;  B5Z887, PIMT_HELPG ;  Q9ZKC2, PIMT_HELPJ ;
DR   P56133, PIMT_HELPY ;  A9AUP1, PIMT_HERA2 ;  A4G4J3, PIMT_HERAR ;
DR   P22061, PIMT_HUMAN ;  A2BKH8, PIMT_HYPBU ;  Q5QUB2, PIMT_IDILO ;
DR   A8AAV7, PIMT_IGNH4 ;  A6SZX9, PIMT_JANMA ;  Q28TH8, PIMT_JANSC ;
DR   B5XV38, PIMT_KLEP3 ;  A6TD35, PIMT_KLEP7 ;  B1L6T9, PIMT_KORCO ;
DR   Q1MRE5, PIMT_LAWIP ;  B1Y0T0, PIMT_LEPCP ;  Q4R5H0, PIMT_MACFA ;
DR   Q2W4A2, PIMT_MAGSA ;  A0L4K5, PIMT_MAGSM ;  Q0ANE2, PIMT_MARMM ;
DR   A6UWM1, PIMT_META3 ;  A7I4W9, PIMT_METB6 ;  Q12UV0, PIMT_METBU ;
DR   A9VY77, PIMT_METEP ;  Q1H095, PIMT_METFK ;  Q2FRW3, PIMT_METHJ ;
DR   Q57636, PIMT_METJA ;  Q8TYL4, PIMT_METKA ;  A4G087, PIMT_METM5 ;
DR   A9A8I9, PIMT_METM6 ;  A6VI91, PIMT_METM7 ;  Q8PW90, PIMT_METMA ;
DR   A3CXP8, PIMT_METMJ ;  Q6M116, PIMT_METMP ;  B1ZJW1, PIMT_METPB ;
DR   A2SF76, PIMT_METPP ;  O26915, PIMT_METTH ;  A0B9U1, PIMT_METTP ;
DR   A6UR90, PIMT_METVS ;  P23506, PIMT_MOUSE ;  Q1D6W9, PIMT_MYXXD ;
DR   B2A578, PIMT_NATTJ ;  Q0ADP2, PIMT_NITEC ;  Q82VW0, PIMT_NITEU ;
DR   Q3SRQ7, PIMT_NITWN ;  A6X6Y1, PIMT_OCHA4 ;  B6JFP0, PIMT_OLICO ;
DR   B1ZPF0, PIMT_OPITP ;  A1B5M0, PIMT_PARDP ;  A7HXK6, PIMT_PARL1 ;
DR   Q6MCW9, PIMT_PARUW ;  C6DDF9, PIMT_PECCP ;  Q3A4N4, PIMT_PELCD ;
DR   Q3B1L6, PIMT_PELLD ;  B4SFU3, PIMT_PELPB ;  A5CYQ6, PIMT_PELTS ;
DR   A9BH07, PIMT_PETMO ;  Q7N8K3, PIMT_PHOLL ;  Q6LMT7, PIMT_PHOPR ;
DR   P80895, PIMT_PIG   ;  Q5RA89, PIMT_PONAB ;  B4F223, PIMT_PROMH ;
DR   A4SGH4, PIMT_PROVI ;  Q48F88, PIMT_PSE14 ;  Q15P27, PIMT_PSEA6 ;
DR   A6V1G4, PIMT_PSEA7 ;  B7V8C3, PIMT_PSEA8 ;  Q02R96, PIMT_PSEAB ;
DR   P45683, PIMT_PSEAE ;  Q1I655, PIMT_PSEE4 ;  Q4KHE7, PIMT_PSEF5 ;
DR   C3K706, PIMT_PSEFS ;  Q3IDD2, PIMT_PSEHT ;  A4XWR1, PIMT_PSEMY ;
DR   A5W820, PIMT_PSEP1 ;  Q3KH83, PIMT_PSEPF ;  B0KSC8, PIMT_PSEPG ;
DR   Q88MF0, PIMT_PSEPK ;  B1JB29, PIMT_PSEPW ;  Q886L4, PIMT_PSESM ;
DR   Q4ZWP9, PIMT_PSEU2 ;  A4VJV3, PIMT_PSEU5 ;  Q9UXX0, PIMT_PYRAB ;
DR   Q8ZYN0, PIMT_PYRAE ;  A4WNC5, PIMT_PYRAR ;  A3MY16, PIMT_PYRCJ ;
DR   Q8TZR3, PIMT_PYRFU ;  O59534, PIMT_PYRHO ;  A1RSC6, PIMT_PYRIL ;
DR   Q8Y039, PIMT_RALSO ;  P22062, PIMT_RAT   ;  O08249, PIMT_RHIME ;
DR   B6ISM3, PIMT_RHOCS ;  Q07N42, PIMT_RHOP5 ;  Q6NCU3, PIMT_RHOPA ;
DR   Q214W4, PIMT_RHOPB ;  Q136H9, PIMT_RHOPS ;  Q2RTH7, PIMT_RHORT ;
DR   A3PIZ8, PIMT_RHOS1 ;  Q3J3D1, PIMT_RHOS4 ;  A4WU05, PIMT_RHOS5 ;
DR   B9KQZ1, PIMT_RHOSK ;  A7NI01, PIMT_ROSCS ;  Q163U2, PIMT_ROSDO ;
DR   A5UZW2, PIMT_ROSS1 ;  Q21LB7, PIMT_SACD2 ;  B5F407, PIMT_SALA4 ;
DR   A9MF32, PIMT_SALAR ;  Q57KJ8, PIMT_SALCH ;  B5FTS1, PIMT_SALDC ;
DR   B5QW14, PIMT_SALEP ;  B5RDP9, PIMT_SALG2 ;  B4TFW3, PIMT_SALHS ;
DR   B4T453, PIMT_SALNS ;  Q5PEE9, PIMT_SALPA ;  A9N1H6, PIMT_SALPB ;
DR   C0PXA3, PIMT_SALPC ;  B5BEY0, PIMT_SALPK ;  Q2S176, PIMT_SALRD ;
DR   B4TTV7, PIMT_SALSV ;  Q8Z474, PIMT_SALTI ;  Q8ZMF9, PIMT_SALTY ;
DR   Q9URZ1, PIMT_SCHPO ;  A8G9Z6, PIMT_SERP5 ;  A1S4E3, PIMT_SHEAM ;
DR   B8E8T7, PIMT_SHEB2 ;  A3D789, PIMT_SHEB5 ;  A6WR22, PIMT_SHEB8 ;
DR   A9KYG4, PIMT_SHEB9 ;  Q12PY8, PIMT_SHEDO ;  Q086A4, PIMT_SHEFN ;
DR   B0TK10, PIMT_SHEHH ;  A3QC83, PIMT_SHELP ;  Q8EBR6, PIMT_SHEON ;
DR   A8H1T1, PIMT_SHEPA ;  A4Y937, PIMT_SHEPC ;  B8CJQ2, PIMT_SHEPW ;
DR   A0KU88, PIMT_SHESA ;  Q0HL66, PIMT_SHESM ;  Q0HXG4, PIMT_SHESR ;
DR   A1RHF9, PIMT_SHESW ;  B1KPT0, PIMT_SHEWM ;  B2TZI8, PIMT_SHIB3 ;
DR   Q31XA5, PIMT_SHIBS ;  Q32CI7, PIMT_SHIDS ;  Q0T1H4, PIMT_SHIF8 ;
DR   Q83JY3, PIMT_SHIFL ;  Q3YYB9, PIMT_SHISS ;  Q5LQ09, PIMT_SILPO ;
DR   Q1GFP1, PIMT_SILST ;  Q2NVM1, PIMT_SODGM ;  A3DMG3, PIMT_STAMF ;
DR   B4SR93, PIMT_STRM5 ;  B2FK95, PIMT_STRMK ;  Q2LUT4, PIMT_SYNAS ;
DR   Q2JJN4, PIMT_SYNJB ;  B1XQE1, PIMT_SYNP2 ;  A6LNM3, PIMT_THEM4 ;
DR   Q56308, PIMT_THEMA ;  B1YC47, PIMT_THENV ;  B6YX51, PIMT_THEON ;
DR   C6A3F2, PIMT_THESM ;  Q3SKJ2, PIMT_THIDA ;  Q0W2W0, PIMT_UNCMA ;
DR   A5F9C1, PIMT_VIBC3 ;  Q9KUI8, PIMT_VIBCH ;  C3LS22, PIMT_VIBCM ;
DR   Q5E332, PIMT_VIBF1 ;  B5FAF3, PIMT_VIBFM ;  A7MTT6, PIMT_VIBHB ;
DR   Q87LQ6, PIMT_VIBPA ;  B7VK62, PIMT_VIBSL ;  Q8DC56, PIMT_VIBVU ;
DR   Q7MHQ8, PIMT_VIBVY ;  Q43209, PIMT_WHEAT ;  Q8PLR3, PIMT_XANAC ;
DR   Q3BUS3, PIMT_XANC5 ;  Q4UTP9, PIMT_XANC8 ;  B0RTZ8, PIMT_XANCB ;
DR   Q8P9Y6, PIMT_XANCP ;  Q2P1L5, PIMT_XANOM ;  B2SUB3, PIMT_XANOP ;
DR   Q5GYL2, PIMT_XANOR ;  A7INP1, PIMT_XANP2 ;  B2I8X8, PIMT_XYLF2 ;
DR   Q9PF21, PIMT_XYLFA ;  B0U4U6, PIMT_XYLFM ;  Q87AK5, PIMT_XYLFT ;
DR   A1JJT8, PIMT_YERE8 ;  A7FLX4, PIMT_YERP3 ;  Q1C474, PIMT_YERPA ;
DR   B2K581, PIMT_YERPB ;  Q8ZBQ0, PIMT_YERPE ;  A9R115, PIMT_YERPG ;
DR   Q1CLR2, PIMT_YERPN ;  A4TQ01, PIMT_YERPP ;  Q66EB9, PIMT_YERPS ;
DR   B1JJF4, PIMT_YERPY ;
//
ID   2.1.1.78
DE   Isoorientin 3'-O-methyltransferase.
CA   S-adenosyl-L-methionine + isoorientin = S-adenosyl-L-homocysteine +
CA   isoscoparin.
CC   -!- Also acts on isoorientin 2''-O-rhamnoside.
CC   -!- Involved in the biosynthesis of flavones.
//
ID   2.1.1.79
DE   Cyclopropane-fatty-acyl-phospholipid synthase.
AN   CFA synthase.
AN   Cyclopropane fatty acid synthase.
AN   Cyclopropane synthetase.
AN   Unsaturated-phospholipid methyltransferase.
CA   S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-
CA   L-homocysteine + phospholipid cyclopropane fatty acid.
CC   -!- Adds a methylene group across the 9,10 position of a Delta(9)-
CC       olefinic acyl chain in phosphatidylethanolamine or, more slowly,
CC       phosphatidylglycerol or phosphatidylinositol forming a cyclopropane
CC       derivative (cf. EC 2.1.1.16).
DR   P45509, CFA_CITFR  ;  P0A9H8, CFA_ECOL6  ;  P0A9H7, CFA_ECOLI  ;
DR   A5U866, CMAS1_MYCTA;  P0C5C2, CMAS1_MYCTU;  P0A5P1, CMAS2_MYCBO;
DR   Q49807, CMAS2_MYCLE;  P0A5P0, CMAS2_MYCTU;  Q7D9R5, CMAS3_MYCTU;
DR   Q7U1J9, MMAA2_MYCBO;  A5U029, MMAA2_MYCTA;  Q79FX6, MMAA2_MYCTU;
//
ID   2.1.1.80
DE   Protein-glutamate O-methyltransferase.
AN   Methyl-accepting chemotaxis protein O-methyltransferase.
CA   S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine
CA   + protein L-glutamate methyl ester.
CC   -!- Forms ester groups with L-glutamate residues in a number of membrane
CC       proteins.
CC   -!- Formerly EC 2.1.1.24.
DR   O87131, CHER1_PSEAE;  Q9KQ06, CHER1_VIBCH;  Q9I6V7, CHER2_PSEAE;
DR   Q9KS61, CHER2_VIBCH;  Q9KKL3, CHER3_VIBCH;  Q9KCB8, CHER_BACHD ;
DR   P31105, CHER_BACSU ;  O51069, CHER_BORBU ;  Q0P9X6, CHER_CAMJE ;
DR   A1VZQ6, CHER_CAMJJ ;  P07364, CHER_ECOLI ;  P21824, CHER_ENTAE ;
DR   Q92DX0, CHER_LISIN ;  Q9XDE8, CHER_LISMO ;  Q2KCH9, CHER_RHIEC ;
DR   P07801, CHER_SALTY ;  Q9WYT5, CHER_THEMA ;  Q57508, CHER_VIBAN ;
DR   Q9X9K2, CHER_VIBPA ;  P31759, FRZF_MYXXA ;
//
ID   2.1.1.81
DE   Transferred entry: 2.1.1.49.
//
ID   2.1.1.82
DE   3-methylquercetin 7-O-methyltransferase.
AN   3-methylquercitin 7-O-methyltransferase.
AN   7-OMT.
AN   Flavonol 7-methyltransferase.
AN   Flavonol 7-O-methyltransferase.
CA   S-adenosyl-L-methionine + 3',4',5,7-tetrahydroxy-3-methoxyflavone =
CA   S-adenosyl-L-homocysteine + 3',4',5-trihydroxy-3,7-dimethoxyflavone.
CC   -!- Involved with EC 2.1.1.76 and EC 2.1.1.83 in the methylation of
CC       quercetin to 3,7,4'-trimethylquercetin in Chrysosplenium americanum.
CC   -!- Does not act on flavones, dihydroflavonols, or their glucosides.
//
ID   2.1.1.83
DE   3,7-dimethylquercetin 4'-O-methyltransferase.
AN   3,7-dimethylquercitin 4'-O-methyltransferase.
AN   4'-OMT.
AN   Flavonol 4'-methyltransferase.
AN   Flavonol 4'-O-methyltransferase.
CA   S-adenosyl-L-methionine + 3',4',5-trihydroxy-3,7-dimethoxyflavone =
CA   S-adenosyl-L-homocysteine + 3',5-dihydroxy-3,4',7-trimethoxyflavone.
CC   -!- 3,7-dimethylquercetagetin can also act as acceptor.
CC   -!- Involved with EC 2.1.1.76 and EC 2.1.1.82 in the methylation of
CC       quercetin to 3,7,4'-trimethylquercetin in Chrysosplenium americanum.
CC   -!- Does not act on flavones, dihydroflavonols, or their glucosides.
//
ID   2.1.1.84
DE   Methylquercetagetin 6-O-methyltransferase.
AN   Flavonol 6-O-methyltransferase.
CA   S-adenosyl-L-methionine + 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone =
CA   S-adenosyl-L-homocysteine + 3',4',5-trihydroxy-3,6,7-trimethoxyflavone.
CC   -!- The enzymes from Chrysosplenium americanum also methylates
CC       3,7,3'-trimethylquercetagetin at the 6-position.
CC   -!- Does not act on flavones, dihydroflavonols, or their glucosides.
//
ID   2.1.1.85
DE   Protein-histidine N-methyltransferase.
AN   Protein methylase IV.
CA   S-adenosyl-L-methionine + protein L-histidine = S-adenosyl-L-homocysteine
CA   + protein N(tau)-methyl-L-histidine.
CC   -!- Highly specific for histidine residues, for example, in actin.
DR   Q9UTQ8, HPM1_SCHPO ;  P40481, HPM1_YEAST ;
//
ID   2.1.1.86
DE   Tetrahydromethanopterin S-methyltransferase.
AN   N(5)-methyltetrahydromethanopterin--coenzyme M methyltransferase.
AN   Tetrahydromethanopterin methyltransferase.
CA   5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate =
CA   5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate.
CC   -!- Involved in the formation of methane from CO in methanogenic archaea.
DR   D3E045, MTRA1_METRM;  O27227, MTRA1_METTH;  P80184, MTRA1_METTM;
DR   D3E0P6, MTRA2_METRM;  O27134, MTRA2_METTH;  D9PXT1, MTRA2_METTM;
DR   A6UWH7, MTRA_META3 ;  Q8TU03, MTRA_METAC ;  Q9Y8K4, MTRA_METBF ;
DR   D7EBK7, MTRA_METEZ ;  C7P879, MTRA_METFA ;  Q2FRN2, MTRA_METHJ ;
DR   Q58261, MTRA_METJA ;  O32867, MTRA_METKA ;  A6VHF2, MTRA_METM7 ;
DR   O59640, MTRA_METMA ;  Q6LWZ0, MTRA_METMP ;  D5E7Y7, MTRA_METMS ;
DR   Q2NI29, MTRA_METST ;  D7DUI0, MTRA_METV3 ;  A6UWH6, MTRB_META3 ;
DR   Q8TU02, MTRB_METAC ;  Q9Y8K3, MTRB_METBF ;  Q58260, MTRB_METJA ;
DR   O32866, MTRB_METKA ;  A4FVW2, MTRB_METM5 ;  A6VHF1, MTRB_METM7 ;
DR   P80655, MTRB_METMA ;  Q6LWZ1, MTRB_METMP ;  O27228, MTRB_METTH ;
DR   Q59584, MTRB_METTM ;  A6UQK9, MTRB_METVS ;  Q8TU01, MTRC_METAC ;
DR   Q9Y8K2, MTRC_METBF ;  Q58259, MTRC_METJA ;  O32865, MTRC_METKA ;
DR   A4FVW3, MTRC_METM5 ;  A6VHF0, MTRC_METM7 ;  O59638, MTRC_METMA ;
DR   Q6LWZ2, MTRC_METMP ;  O27229, MTRC_METTH ;  P80185, MTRC_METTM ;
DR   A6UQK8, MTRC_METVS ;  Q8TU00, MTRD_METAC ;  Q9Y8K1, MTRD_METBF ;
DR   Q58258, MTRD_METJA ;  O32864, MTRD_METKA ;  P80653, MTRD_METMA ;
DR   Q6LWZ3, MTRD_METMP ;  O27230, MTRD_METTH ;  P80183, MTRD_METTM ;
DR   A6UWH3, MTRE_META3 ;  Q8TTZ9, MTRE_METAC ;  Q9Y8K0, MTRE_METBF ;
DR   Q12VU4, MTRE_METBU ;  Q49176, MTRE_METFE ;  Q58257, MTRE_METJA ;
DR   Q49606, MTRE_METKA ;  A4FVW5, MTRE_METM5 ;  A6VHE8, MTRE_METM7 ;
DR   P80651, MTRE_METMA ;  Q6LWZ4, MTRE_METMP ;  O27231, MTRE_METTH ;
DR   P80186, MTRE_METTM ;  Q50830, MTRE_METVA ;  A6UQK6, MTRE_METVS ;
DR   Q8TU04, MTRF_METAC ;  Q9Y8K5, MTRF_METBF ;  Q58262, MTRF_METJA ;
DR   Q8TVA7, MTRF_METKA ;  P80654, MTRF_METMA ;  O27226, MTRF_METTH ;
DR   Q50773, MTRF_METTM ;  Q8TU05, MTRG_METAC ;  Q9Y8K6, MTRG_METBF ;
DR   Q58263, MTRG_METJA ;  O32868, MTRG_METKA ;  P80656, MTRG_METMA ;
DR   Q6LWY8, MTRG_METMP ;  O27225, MTRG_METTH ;  Q50774, MTRG_METTM ;
DR   A6UWI0, MTRH_META3 ;  Q8TU06, MTRH_METAC ;  O93716, MTRH_METBF ;
DR   Q58264, MTRH_METJA ;  O32869, MTRH_METKA ;  A4FVV8, MTRH_METM5 ;
DR   P80650, MTRH_METMA ;  Q6LWY7, MTRH_METMP ;  O27224, MTRH_METTH ;
DR   P80187, MTRH_METTM ;  A6UQL3, MTRH_METVS ;  P80652, TM2A_METMA ;
//
ID   2.1.1.87
DE   Pyridine N-methyltransferase.
CA   S-adenosyl-L-methionine + pyridine = S-adenosyl-L-homocysteine +
CA   N-methylpyridinium.
//
ID   2.1.1.88
DE   8-hydroxyquercetin 8-O-methyltransferase.
AN   8-hydroxyquercitin 8-O-methyltransferase.
AN   Flavonol 8-O-methyltransferase.
CA   S-adenosyl-L-methionine + 3,3',4',5,7,8-hexahydroxyflavone = S-adenosyl-
CA   L-homocysteine + 3,3',4',5,7-pentahydroxy-8-methoxyflavone.
CC   -!- Also acts on 8-hydroxykaempferol, but not on the glycosides of
CC       8-hydroxyflavonols.
CC   -!- An enzyme from the flower buds of Lotus corniculatus.
DR   Q6VMW0, Q8OMT_MENPI;
//
ID   2.1.1.89
DE   Tetrahydrocolumbamine 2-O-methyltransferase.
CA   S-adenosyl-L-methionine + 5,8,13,13a-tetrahydrocolumbamine = S-adenosyl-
CA   L-homocysteine + tetrahydropalmatine.
CC   -!- Involved in the biosynthesis of the berberine alkaloids.
DR   Q8H9A8, COOMT_COPJA;
//
ID   2.1.1.90
DE   Methanol--5-hydroxybenzimidazolylcobamide Co-methyltransferase.
CA   Methanol + 5-hydroxybenzimidazolylcobamide = Co-methyl-Co-5-
CA   hydroxybenzimidazolylcob(I)amide + H(2)O.
CC   -!- The enzyme from Methanosarcina barkeri contains 3-4 molecules of
CC       bound 5-hydroxybenzimidazolylcobamide which act as methyl acceptor.
CC   -!- Inactivated by oxygen and other oxidizing agents, and reactivated by
CC       catalytic amounts of ATP and hydrogen.
//
ID   2.1.1.91
DE   Isobutyraldoxime O-methyltransferase.
AN   Aldoxime methyltransferase.
CA   S-adenosyl-L-methionine + 2-methylpropanal oxime = S-adenosyl-L-
CA   homocysteine + 2-methylpropanal O-methyloxime.
CC   -!- Oximes of C(4) to C(6) aldehydes can act as acceptors.
CC   -!- The most active substrate is 2-methylbutyraldoxime.
//
ID   2.1.1.92
DE   Transferred entry: 2.1.1.69.
//
ID   2.1.1.93
DE   Transferred entry: 2.1.1.70.
//
ID   2.1.1.94
DE   Tabersonine 16-O-methyltransferase.
AN   11-demethyl-17-deacetylvindoline 11-methyltransferase.
AN   11-O-demethyl-17-O-deacetylvindoline O-methyltransferase.
AN   S-adenosyl-L-methionine:11-O-demethyl-17-O-deacetylvindoline 11-O-
AN   methyltransferase.
CA   S-adenosyl-L-methionine + 16-hydroxytabersonine = S-adenosyl-L-
CA   homocysteine + 16-methoxytabersonine.
CC   -!- Involved in the biosynthesis of vindoline from tabersonine in the
CC       Madagascar periwinkle, Catharanthus roseus.
DR   B0EXJ8, HTOMT_CATRO;
//
ID   2.1.1.95
DE   Tocopherol O-methyltransferase.
CA   S-adenosyl-L-methionine + gamma-tocopherol = S-adenosyl-L-homocysteine +
CA   alpha-tocopherol.
DR   Q9ZSK1, GTOMC_ARATH;  Q6ZIK0, GTOMC_ORYSJ;
//
ID   2.1.1.96
DE   Thioether S-methyltransferase.
CA   S-adenosyl-L-methionine + dimethyl sulfide = S-adenosyl-L-homocysteine +
CA   trimethylsulfonium.
CC   -!- Also acts on dimethyl selenide, dimethyl telluride, diethyl sulfide,
CC       1,4-dithiane and many other thioethers.
PR   PROSITE; PDOC00844;
//
ID   2.1.1.97
DE   3-hydroxyanthranilate 4-C-methyltransferase.
CA   S-adenosyl-L-methionine + 3-hydroxyanthranilate = S-adenosyl-L-
CA   homocysteine + 3-hydroxy-4-methylanthranilate.
CC   -!- Involved in the biosynthesis of the antibiotic actinomycin in
CC       Streptomyces antibioticus.
//
ID   2.1.1.98
DE   Diphthine synthase.
CA   3 S-adenosyl-L-methionine + 2-(3-carboxy-3-aminopropyl)-L-histidine =
CA   3 S-adenosyl-L-homocysteine + 2-(3-carboxy-3-(trimethylammonio)propyl)-L-
CA   histidine.
CC   -!- 2-(3-carboxy-3-(methylammonio)propyl)-L-histidine and the
CC       corresponding dimethyl compound can also act as acceptors.
CC   -!- The trimethylated product, diphthine, is converted into diphthamide
CC       by EC 6.3.2.22.
DR   O81769, DPH5_ARATH ;  Q754E7, DPH5_ASHGO ;  Q6MY91, DPH5_ASPFU ;
DR   Q5E982, DPH5_BOVIN ;  Q59NX9, DPH5_CANAL ;  Q6FXK9, DPH5_CANGA ;
DR   Q6BN80, DPH5_DEBHA ;  Q75JG8, DPH5_DICDI ;  Q5BFG0, DPH5_EMENI ;
DR   Q4HZI0, DPH5_GIBZE ;  Q9H2P9, DPH5_HUMAN ;  Q6CIZ1, DPH5_KLULA ;
DR   Q9CWQ0, DPH5_MOUSE ;  Q7S949, DPH5_NEUCR ;  O74898, DPH5_SCHPO ;
DR   Q6C1E0, DPH5_YARLI ;  P32469, DPH5_YEAST ;  Q9YDI2, DPHB_AERPE ;
DR   O29866, DPHB_ARCFU ;  B9LV13, DPHB_HALLT ;  Q5V2B7, DPHB_HALMA ;
DR   B0R4W9, DPHB_HALS3 ;  Q9HQK6, DPHB_HALSA ;  Q18JS3, DPHB_HALWD ;
DR   A6UU49, DPHB_META3 ;  Q8TR14, DPHB_METAC ;  A7IA21, DPHB_METB6 ;
DR   Q467Z4, DPHB_METBF ;  Q12XB4, DPHB_METBU ;  Q2FQ45, DPHB_METHJ ;
DR   Q58670, DPHB_METJA ;  Q8TXC7, DPHB_METKA ;  A2SQF6, DPHB_METLZ ;
DR   A4FYP1, DPHB_METM5 ;  A9A6D8, DPHB_METM6 ;  A6VJP1, DPHB_METM7 ;
DR   Q8PUH9, DPHB_METMA ;  A3CWF9, DPHB_METMJ ;  Q6LZN6, DPHB_METMP ;
DR   B8GIF8, DPHB_METPE ;  A4YHI8, DPHB_METS5 ;  Q2NFJ8, DPHB_METST ;
DR   O27902, DPHB_METTH ;  A0B879, DPHB_METTP ;  A6US81, DPHB_METVS ;
DR   Q3IS55, DPHB_NATPD ;  Q9UZ31, DPHB_PYRAB ;  Q8ZXR9, DPHB_PYRAE ;
DR   A3MU14, DPHB_PYRCJ ;  Q8U377, DPHB_PYRFU ;  O58456, DPHB_PYRHO ;
DR   A1RU15, DPHB_PYRIL ;  Q5JFE7, DPHB_PYRKO ;  A3DLV7, DPHB_STAMF ;
DR   C3N5D1, DPHB_SULIA ;  C4KGZ7, DPHB_SULIK ;  C3MPQ5, DPHB_SULIL ;
DR   C3MYP9, DPHB_SULIM ;  C3NHR8, DPHB_SULIN ;  C3NDY5, DPHB_SULIY ;
DR   Q97TX8, DPHB_SULSO ;  Q971V1, DPHB_SULTO ;  Q9HJT0, DPHB_THEAC ;
DR   C5A3K4, DPHB_THEGJ ;  B1YAU2, DPHB_THENV ;  B6YXP9, DPHB_THEON ;
DR   Q979Z8, DPHB_THEVO ;  Q0W085, DPHB_UNCMA ;
//
ID   2.1.1.99
DE   3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase.
AN   16-methoxy-2,3-dihydro-3-hydroxytabersonine methyltransferase.
AN   16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase.
AN   NMT.
AN   S-adenosyl-L-methionine:16-methoxy-2,3-dihydro-3-hydroxytabersonine
AN   N-methyltransferase.
CA   S-adenosyl-L-methionine + 3-hydroxy-16-methoxy-2,3-dihydrotabersonine =
CA   S-adenosyl-L-homocysteine + deacetoxyvindoline.
CC   -!- Involved in the biosynthesis of vindoline from tabersonine in the
CC       Madagascar periwinkle Catharanthus roseus.
//
ID   2.1.1.100
DE   Protein-S-isoprenylcysteine O-methyltransferase.
AN   Isoprenylcysteine carboxylmethyltransferase.
AN   Prenylated protein carboxyl methyltransferase.
AN   Prenylcysteine carboxyl methyltransferase.
CA   S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine =
CA   S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine
CA   methyl ester.
CC   -!- C-terminal S-geranylgeranylcysteine and S-geranylcysteine residues
CC       are also methylated, more slowly.
CC   -!- Formerly EC 2.1.1.24.
DR   Q9FMW9, ICMTA_ARATH;  Q93W54, ICMTB_ARATH;  Q558K8, ICMT_DICDI ;
DR   O60725, ICMT_HUMAN ;  Q9EQK7, ICMT_MOUSE ;  A2XX73, ICMT_ORYSI ;
DR   Q7XSR9, ICMT_ORYSJ ;  Q9WVM4, ICMT_RAT   ;  O12947, ICMT_XENLA ;
DR   P87014, MAM4_SCHPO ;  P32584, STE14_YEAST;
//
ID   2.1.1.101
DE   Macrocin O-methyltransferase.
CA   S-adenosyl-L-methionine + macrocin = S-adenosyl-L-homocysteine + tylosin.
CC   -!- The 3-hydroxyl group of a 2-O-methyl-6-deoxy-D-allose residue in the
CC       macrolide antibiotic macrocin acts as methyl acceptor; also converts
CC       lactenosin into desmyocin.
CC   -!- Not identical with EC 2.1.1.102.
//
ID   2.1.1.102
DE   Demethylmacrocin O-methyltransferase.
CA   S-adenosyl-L-methionine + demethylmacrocin = S-adenosyl-L-homocysteine +
CA   macrocin.
CC   -!- The 2-hydroxyl group of a 6-deoxy-D-allose residue in
CC       demethylmacrocin acts as methyl acceptor.
CC   -!- Not identical with EC 2.1.1.101.
//
ID   2.1.1.103
DE   Phosphoethanolamine N-methyltransferase.
CA   S-adenosyl-L-methionine + ethanolamine phosphate = S-adenosyl-L-
CA   homocysteine + N-methylethanolamine phosphate.
CC   -!- The enzyme may catalyze the transfer of two further methyl groups to
CC       the product.
DR   Q9FR44, PEAM1_ARATH;  Q944H0, PEAM2_ARATH;  Q9C6B9, PEAM3_ARATH;
DR   Q9M571, PEAMT_SPIOL;
//
ID   2.1.1.104
DE   Caffeoyl-CoA O-methyltransferase.
AN   Trans-caffeoyl-CoA 3-O-methyltransferase.
CA   S-adenosyl-L-methionine + caffeoyl-CoA = S-adenosyl-L-homocysteine +
CA   feruloyl-CoA.
DR   Q9C9W3, CAMT1_ARATH;  Q86IC9, CAMT1_DICDI;  O81185, CAMT1_EUCGL;
DR   Q9XGD6, CAMT1_MAIZE;  O65862, CAMT1_POPTR;  O24144, CAMT1_TOBAC;
DR   Q9C9W4, CAMT2_ARATH;  Q86IC8, CAMT2_DICDI;  Q9SWB8, CAMT2_EUCGL;
DR   Q9XGD5, CAMT2_MAIZE;  O65922, CAMT2_POPTR;  O24149, CAMT2_TOBAC;
DR   Q9C5D7, CAMT3_ARATH;  Q55AS5, CAMT3_DICDI;  O24150, CAMT3_TOBAC;
DR   O49499, CAMT4_ARATH;  O24151, CAMT4_TOBAC;  O04899, CAMT5_TOBAC;
DR   Q42945, CAMT6_TOBAC;  Q9SLP8, CAMT_CITNA ;  O04854, CAMT_EUCGU ;
DR   Q40313, CAMT_MEDSA ;  O65162, CAMT_MESCR ;  P28034, CAMT_PETCR ;
DR   P81081, CAMT_PINPS ;  Q9ZTT5, CAMT_PINTA ;  P93711, CAMT_POPKI ;
DR   Q43095, CAMT_POPTM ;  Q8H9B6, CAMT_SOLTU ;  Q43161, CAMT_STELP ;
DR   Q43237, CAMT_VITVI ;  Q41720, CAMT_ZINEL ;
//
ID   2.1.1.105
DE   N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase.
CA   S-adenosyl-L-methionine + N-benzoyl-4-hydroxyanthranilate = S-adenosyl-L-
CA   homocysteine + N-benzoyl-4-methoxyanthranilate.
CC   -!- Involved in the biosynthesis of phytoalexins.
//
ID   2.1.1.106
DE   Tryptophan 2-C-methyltransferase.
CA   S-adenosyl-L-methionine + L-tryptophan = S-adenosyl-L-homocysteine + L-2-
CA   methyltryptophan.
CC   -!- D-tryptophan and (indol-3-yl)pyruvate can also act as acceptors,
CC       but more slowly.
//
ID   2.1.1.107
DE   Uroporphyrinogen-III C-methyltransferase.
AN   Adenosylmethionine-uroporphyrinogen III methyltransferase.
AN   S-adenosyl-L-methionine-dependent uroporphyrinogen III methylase.
AN   SUMT.
AN   Urogen III methylase.
AN   Uroporphyrin-III C-methyltransferase.
AN   Uroporphyrinogen III methylase.
AN   Uroporphyrinogen methyltransferase.
AN   Uroporphyrinogen-III methylase.
AN   Uroporphyrinogen-III methyltransferase.
CA   (1) S-adenosyl-L-methionine + uroporphyrinogen III = S-adenosyl-L-
CA   homocysteine + precorrin-1.
CA   (2) S-adenosyl-L-methionine + precorrin-1 = S-adenosyl-L-homocysteine +
CA   precorrin-2.
CC   -!- This enzyme catalyzes two sequential methylation reactions, the first
CC       forming precorrin-1 and the second leading to the formation of
CC       precorrin-2.
CC   -!- It is the first of three steps leading to the formation of siroheme
CC       from uroporphyrinogen III.
CC   -!- The second step involves an NAD(+)-dependent dehydrogenation to form
CC       sirohydrochlorin from precorrin-2 (EC 1.3.1.76) and the third step
CC       involves the chelation of Fe(2+) to sirohydrochlorin to form siroheme
CC       (EC 4.99.1.4).
CC   -!- In Saccharomyces cerevisiae, the last two steps are carried out by a
CC       single bifunctional enzyme, Met8p.
CC   -!- In some bacteria, steps 1-3 are catalyzed by a single multifunctional
CC       protein called CysG, whereas in Bacillus megaterium, three separate
CC       enzymes carry out each of the steps, with SirA being responsible for
CC       the above reaction.
CC   -!- Also involved in the biosynthesis of cobalamin.
PR   PROSITE; PDOC00656;
DR   A0KLD7, CYSG1_AERHH;  A4SHL4, CYSG1_AERS4;  A7MJ67, CYSG1_ENTS8;
DR   Q6D1A4, CYSG1_ERWCT;  A1WWP8, CYSG1_HALHL;  A6TD45, CYSG1_KLEP7;
DR   A8G9Y3, CYSG1_SERP5;  A1JJS8, CYSG1_YERE8;  A7FLY4, CYSG1_YERP3;
DR   Q1CLS2, CYSG1_YERPN;  A4TGU8, CYSG1_YERPP;  Q66EC9, CYSG1_YERPS;
DR   A0KP37, CYSG2_AERHH;  A4SRH0, CYSG2_AERS4;  A7MKK9, CYSG2_ENTS8;
DR   Q6CZS0, CYSG2_ERWCT;  A1WYD5, CYSG2_HALHL;  A6TF07, CYSG2_KLEP7;
DR   A8GKQ1, CYSG2_SERP5;  A1JSB7, CYSG2_YERE8;  A7FNS9, CYSG2_YERP3;
DR   Q1CCP6, CYSG2_YERPN;  A4TPZ1, CYSG2_YERPP;  Q664M6, CYSG2_YERPS;
DR   A0KQJ4, CYSG3_AERHH;  Q6F8G6, CYSG_ACIAD ;  B3GZA0, CYSG_ACTP7 ;
DR   B0BTC2, CYSG_ACTPJ ;  A6VPZ6, CYSG_ACTSZ ;  Q0VQ05, CYSG_ALCBS ;
DR   Q0A812, CYSG_ALHEH ;  C1DKY7, CYSG_AZOVD ;  Q1LTP4, CYSG_BAUCH ;
DR   Q7VQG9, CYSG_BLOFL ;  Q493N1, CYSG_BLOPB ;  Q2KWB0, CYSG_BORA1 ;
DR   Q7WMM4, CYSG_BORBR ;  Q7WB57, CYSG_BORPA ;  A9HZV6, CYSG_BORPD ;
DR   Q7VZ77, CYSG_BORPE ;  P57500, CYSG_BUCAI ;  Q7NZV7, CYSG_CHRVO ;
DR   A8AQS4, CYSG_CITK8 ;  A7ZSP4, CYSG_ECO24 ;  B7UK79, CYSG_ECO27 ;
DR   B7MCY5, CYSG_ECO45 ;  B7L4P2, CYSG_ECO55 ;  P0AEA9, CYSG_ECO57 ;
DR   B5YTS6, CYSG_ECO5E ;  B7NMD7, CYSG_ECO7I ;  B7N1F1, CYSG_ECO81 ;
DR   B7M1S1, CYSG_ECO8A ;  C4ZUM4, CYSG_ECOBW ;  B1X716, CYSG_ECODH ;
DR   A8A5H5, CYSG_ECOHS ;  A1AGQ2, CYSG_ECOK1 ;  Q0TC92, CYSG_ECOL5 ;
DR   Q8FCW8, CYSG_ECOL6 ;  B1IP96, CYSG_ECOLC ;  P0AEA8, CYSG_ECOLI ;
DR   B7NDX8, CYSG_ECOLU ;  B6I2S7, CYSG_ECOSE ;  B1LHG9, CYSG_ECOSM ;
DR   Q1R5R3, CYSG_ECOUT ;  C5BGP8, CYSG_EDWI9 ;  A4WFH1, CYSG_ENT38 ;
DR   B7LS75, CYSG_ESCF3 ;  A9H259, CYSG_GLUDA ;  Q5FP95, CYSG_GLUOX ;
DR   Q2SJB7, CYSG_HAHCH ;  Q65T49, CYSG_MANSM ;  Q606C9, CYSG_METCA ;
DR   Q1H3L5, CYSG_METFK ;  A9LZ77, CYSG_NEIM0 ;  P57001, CYSG_NEIMA ;
DR   P95370, CYSG_NEIMB ;  A1KU10, CYSG_NEIMF ;  Q0AHC1, CYSG_NITEC ;
DR   Q820Q4, CYSG_NITEU ;  Q2Y6L7, CYSG_NITMU ;  Q3JCS0, CYSG_NITOC ;
DR   Q7N8L2, CYSG_PHOLL ;  Q6LM67, CYSG_PHOPR ;  Q48H75, CYSG_PSE14 ;
DR   Q15YU1, CYSG_PSEA6 ;  A6V4H6, CYSG_PSEA7 ;  B7UW11, CYSG_PSEA8 ;
DR   Q02NA3, CYSG_PSEAB ;  Q9I0M7, CYSG_PSEAE ;  Q1IBC9, CYSG_PSEE4 ;
DR   Q4K9V8, CYSG_PSEF5 ;  C3JY53, CYSG_PSEFS ;  Q3ILQ9, CYSG_PSEHT ;
DR   A4XUX3, CYSG_PSEMY ;  A5W1H7, CYSG_PSEP1 ;  Q3KA85, CYSG_PSEPF ;
DR   Q88FT3, CYSG_PSEPK ;  B1JBD9, CYSG_PSEPW ;  Q87ZT0, CYSG_PSESM ;
DR   Q4ZRL6, CYSG_PSEU2 ;  A4VLU6, CYSG_PSEU5 ;  Q4FSU1, CYSG_PSYA2 ;
DR   Q1QAX7, CYSG_PSYCK ;  A1SRP9, CYSG_PSYIN ;  A5WEG6, CYSG_PSYWF ;
DR   A1AVU5, CYSG_RUTMC ;  Q21K21, CYSG_SACD2 ;  B5F8J0, CYSG_SALA4 ;
DR   A9MME5, CYSG_SALAR ;  Q57IZ5, CYSG_SALCH ;  B5FJQ1, CYSG_SALDC ;
DR   B5R2C7, CYSG_SALEP ;  B5R7N6, CYSG_SALG2 ;  B4TKQ4, CYSG_SALHS ;
DR   B4SVI1, CYSG_SALNS ;  Q5PLV8, CYSG_SALPA ;  A9MT45, CYSG_SALPB ;
DR   C0Q0F3, CYSG_SALPC ;  B5BH22, CYSG_SALPK ;  B4TY38, CYSG_SALSV ;
DR   Q8Z201, CYSG_SALTI ;  P25924, CYSG_SALTY ;  B2U3H4, CYSG_SHIB3 ;
DR   Q31VS0, CYSG_SHIBS ;  Q32AZ8, CYSG_SHIDS ;  Q0SZU8, CYSG_SHIF8 ;
DR   Q83JB3, CYSG_SHIFL ;  Q3YWQ3, CYSG_SHISS ;  Q2NVN0, CYSG_SODGM ;
DR   Q31GG8, CYSG_THICR ;  Q3SG32, CYSG_THIDA ;  B8GUD3, CYSG_THISH ;
DR   C4LAG5, CYSG_TOLAT ;  A5CXE4, CYSG_VESOH ;  B2I985, CYSG_XYLF2 ;
DR   Q9PF46, CYSG_XYLFA ;  B0U4X0, CYSG_XYLFM ;  Q87AI5, CYSG_XYLFT ;
DR   Q1C2P9, CYSG_YERPA ;  Q74Y23, CYSG_YERPE ;  Q5NRM4, CYSG_ZYMMO ;
DR   Q59294, HEM4_CLOJO ;  P09127, HEMX_ECOLI ;  Q51887, HEMX_PROMI ;
DR   P42437, NASF_BACSU ;  Q51701, NIRE_PARDP ;  P29928, SUMT_BACME ;
DR   O34744, SUMT_BACSU ;  O19889, SUMT_CYACA ;  P29564, SUMT_METIV ;
DR   Q58375, SUMT_METJA ;  Q9I2W4, SUMT_PSEAE ;  P21631, SUMT_PSEDE ;
DR   P37725, SUMT_PSEFL ;  O74468, SUMT_SCHPO ;  P42451, SUMT_SYNE7 ;
DR   Q55749, SUMT_SYNY3 ;  P36150, SUMT_YEAST ;
//
ID   2.1.1.108
DE   6-hydroxymellein O-methyltransferase.
CA   S-adenosyl-L-methionine + 6-hydroxymellein = S-adenosyl-L-homocysteine +
CA   6-methoxymellein.
CC   -!- 3,4-dehydro-6-hydroxymellein can also act as acceptor.
CC   -!- 6-methoxymellein is a phytoalexin produced by carrot tissue.
//
ID   2.1.1.109
DE   Demethylsterigmatocystin 6-O-methyltransferase.
CA   S-adenosyl-L-methionine + 6-demethylsterigmatocystin = S-adenosyl-L-
CA   homocysteine + sterigmatocystin.
CC   -!- Dihydrodemethylsterigmatocystin can also act as acceptor.
CC   -!- Involved in the biosynthesis of aflatoxins in fungi.
//
ID   2.1.1.110
DE   Sterigmatocystin 8-O-methyltransferase.
AN   O-methyltransferase II.
AN   S-adenosyl-L-methionine:sterigmatocystin 7-O-methyltransferase.
AN   Sterigmatocystin 7-O-methyltransferase.
AN   Sterigmatocystin methyltransferase.
CA   S-adenosyl-L-methionine + sterigmatocystin = S-adenosyl-L-homocysteine +
CA   8-O-methylsterigmatocystin.
CC   -!- Dihydrosterigmatocystin can also act as acceptor.
CC   -!- Involved in the biosynthesis of aflatoxins in fungi.
DR   P55790, OMTA_ASPFL ;  Q12120, OMTA_ASPPA ;
//
ID   2.1.1.111
DE   Anthranilate N-methyltransferase.
CA   S-adenosyl-L-methionine + anthranilate = S-adenosyl-L-homocysteine +
CA   N-methylanthranilate.
CC   -!- Involved in the biosynthesis of acridine alkaloids in plant tissues.
DR   A9X7L0, ANMT_RUTGR ;
//
ID   2.1.1.112
DE   Glucuronoxylan 4-O-methyltransferase.
CA   S-adenosyl-L-methionine + glucuronoxylan D-glucuronate = S-adenosyl-L-
CA   homocysteine + glucuronoxylan 4-O-methyl-D-glucuronate.
//
ID   2.1.1.113
DE   Site-specific DNA-methyltransferase (cytosine-N(4)-specific).
AN   Modification methylase.
AN   N(4)-cytosine-specific DNA methylase.
AN   Restriction-modification system.
CA   S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine +
CA   DNA N(4)-methylcytosine.
CC   -!- This is a large group of enzymes, the majority of which, with enzymes
CC       of similar site specificity listed as EC 3.1.21.3, EC 3.1.21.4 and
CC       EC 3.1.21.5, form so-called restriction-modification systems.
CC   -!- See the REBASE database for a complete list of these enzymes:
CC       http://rebase.neb.com/rebase/
PR   PROSITE; PDOC00088;
DR   P0A462, MTA1_ANAVA ;  P0A461, MTA1_NOSS1 ;  P23941, MTB1_BACAM ;
DR   Q9LAI2, MTB1_BACSQ ;  O68556, MTB1_BACSU ;  P70986, MTB1_GEOSE ;
DR   P18051, MTB2_BACAM ;  Q45489, MTB2_BACSU ;  Q04845, MTC1_CITFR ;
DR   P14243, MTC9_CITFR ;  P29568, MTHZ_METTF ;  Q58392, MTM1_METJA ;
DR   Q58843, MTM2_METJA ;  Q58893, MTM5_METJA ;  Q58606, MTM6_METJA ;
DR   P14244, MTMV_MICVA ;  O59647, MTMW_METWO ;  P11409, MTP2_PROHU ;
DR   O52692, MTS1_STRCS ;  O52513, MTS1_STRFI ;  P14230, MTSM_SERMA ;
DR   P30774, MTX1_XANCC ;
//
ID   2.1.1.114
DE   Polyprenyldihydroxybenzoate methyltransferase.
AN   3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase.
AN   DHHB methyltransferase.
AN   DHHB-Mt.
AN   Dihydroxyhexaprenylbenzoate methyltransferase.
CA   S-adenosyl-L-methionine + 3,4-dihydroxy-5-all-trans-polyprenylbenzoate =
CA   S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-5-all-trans-
CA   polyprenylbenzoate.
CC   -!- This enzyme is involved in ubiquinone biosynthesis.
CC   -!- Ubiquinones from different organisms have a different number of
CC       prenyl units (for example, ubiquinone-6 in Saccharomyces, ubiquinone-
CC       9 in rat and ubiquinone-10 in human), and thus the natural substrate
CC       for the enzymes from different organisms has a different number of
CC       prenyl units.
CC   -!- However, the enzyme usually shows a low degree of specificity
CC       regarding the number of prenyl units.
CC   -!- For example, the human COQ3 enzyme can restore biosynthesis of
CC       ubiquinone-6 in coq3 deletion mutants of yeast.
CC   -!- The enzymes from yeast and rat also catalyze the methylation of
CC       3-demethylubiquinol-6 and 3-demethylubiquinol-9, respectively (this
CC       activity is classified as EC 2.1.1.64).
DR   O49354, COQ3_ARATH ;  Q3T131, COQ3_BOVIN ;  O93995, COQ3_CANAL ;
DR   Q54XD0, COQ3_DICDI ;  Q9NZJ6, COQ3_HUMAN ;  Q8BMS4, COQ3_MOUSE ;
DR   Q63159, COQ3_RAT   ;  O74421, COQ3_SCHPO ;  P27680, COQ3_YEAST ;
//
ID   2.1.1.115
DE   (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase.
AN   (RS)-tetrahydrobenzylisoquinoline N-methyltransferase.
AN   Norreticuline N-methyltransferase.
CA   S-adenosyl-L-methionine + (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline =
CA   S-adenosyl-L-homocysteine + N-methyl-(RS)-1-benzyl-1,2,3,4-
CA   tetrahydroisoquinoline.
CC   -!- Broad substrate specificity for (RS)-1-benzyl-1,2,3,4-
CC       tetrahydroisoquinolines; including coclaurine, norcoclaurine,
CC       isococlaurine, norarmepavine, norreticuline and tetrahydropapaverine.
CC   -!- Both R- and S-enantiomers are methylated.
CC   -!- Participates in the pathway leading to benzylisoquinoline alkaloid
CC       synthesis in plants.
CC   -!- The physiological substrate is likely to be coclaurine.
CC   -!- Was earlier termed norreticuline N-methyltransferase.
CC   -!- However, norreticuline has not been found to occur in nature and that
CC       name does not reflect the broad specificity of the enzyme for (RS)-1-
CC       benzyl-1,2,3,4-tetrahydroisoquinolines.
//
ID   2.1.1.116
DE   3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase.
CA   S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine =
CA   S-adenosyl-L-homocysteine + (S)-reticuline.
CC   -!- Involved in isoquinoline alkaloid metabolism in plants.
CC   -!- Has also been shown to catalyze the methylation of (RS)-
CC       laudanosoline, (S)-3'-hydroxycoclaurine and (RS)-7-
CC       O-methylnoraudanosoline.
DR   Q9LEL5, 4OMT_COPJA ;
//
ID   2.1.1.117
DE   (S)-scoulerine 9-O-methyltransferase.
CA   S-adenosyl-L-methionine + (S)-scoulerine = S-adenosyl-L-homocysteine +
CA   (S)-tetrahydrocolumbamine.
CC   -!- The product of this reaction is a precursor for protoberberine
CC       alkaloids in plants.
DR   Q39522, SMT_COPJA  ;
//
ID   2.1.1.118
DE   Columbamine O-methyltransferase.
CA   S-adenosyl-L-methionine + columbamine = S-adenosyl-L-homocysteine +
CA   palmatine.
CC   -!- The product of this reaction is a protoberberine alkaloid that is
CC       widely distributed in the plant kingdom.
CC   -!- Distinct in specificity from EC 2.1.1.88.
DR   Q8H9A8, COOMT_COPJA;
//
ID   2.1.1.119
DE   10-hydroxydihydrosanguinarine 10-O-methyltransferase.
CA   S-adenosyl-L-methionine + 10-hydroxydihydrosanguinarine = S-adenosyl-L-
CA   homocysteine + dihydrochelirubine.
CC   -!- Part of the pathway for synthesis of benzophenanthridine alkaloids in
CC       plants.
//
ID   2.1.1.120
DE   12-hydroxydihydrochelirubine 12-O-methyltransferase.
CA   S-adenosyl-L-methionine + 12-hydroxydihydrochelirubine = S-adenosyl-L-
CA   homocysteine + dihydromacarpine.
CC   -!- Part of the pathway for synthesis of benzophenanthridine alkaloid
CC       macarpine in plants.
//
ID   2.1.1.121
DE   6-O-methylnorlaudanosoline 5'-O-methyltransferase.
CA   S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline = S-adenosyl-L-
CA   homocysteine + nororientaline.
CC   -!- Nororientaline is a precursor of the alkaloid papaverine.
//
ID   2.1.1.122
DE   (S)-tetrahydroprotoberberine N-methyltransferase.
AN   Tetrahydroprotoberberine cis-N-methyltransferase.
CA   S-adenosyl-L-methionine + (S)-7,8,13,14-tetrahydroprotoberberine =
CA   S-adenosyl-L-homocysteine + cis-N-methyl-(S)-7,8,13,14-
CA   tetrahydroprotoberberine.
CC   -!- Involved in the biosynthesis of isoquinoline alkaloids in plants.
DR   C3SBU5, TNMT1_PAPBR;  C3SBU4, TNMT2_PAPBR;  C3SBS8, TNMT_ESCCA ;
DR   Q108P1, TNMT_PAPSO ;
//
ID   2.1.1.123
DE   [Cytochrome c]-methionine S-methyltransferase.
CA   S-adenosyl-L-methionine + [cytochrome c]-methionine = S-adenosyl-L-
CA   homocysteine + [cytochrome c]-S-methyl-methionine.
//
ID   2.1.1.124
DE   [Cytochrome c]-arginine N-methyltransferase.
CA   S-adenosyl-L-methionine + [cytochrome c]-arginine = S-adenosyl-L-
CA   homocysteine + [cytochrome c]-N(omega)-methyl-arginine.
CC   -!- Formerly EC 2.1.1.23.
//
ID   2.1.1.125
DE   Histone-arginine N-methyltransferase.
AN   Histone protein methylase.
AN   Protein methylase I.
AN   Protein-arginine N-methyltransferase.
CA   S-adenosyl-L-methionine + arginine-[histone] = S-adenosyl-L-homocysteine
CA   + N(omega)-methyl-arginine-[histone].
CC   -!- Forms the N(omega)-monomethyl- and N(omega),N(omega')-dimethyl,
CC       but not the N(omega),N(omega)-dimethyl-arginine derivatives.
CC   -!- The name protein methylase I is misleading since it has been used for
CC       a number of enzymes with different specificities.
CC   -!- Formerly EC 2.1.1.23.
DR   Q9SU94, ANM11_ARATH;  Q84W92, ANM13_ARATH;  A3KPF2, ANM14_ARATH;
DR   Q8GWT4, ANM15_ARATH;  Q8AV13, ANM1A_XENLA;  Q6VRB0, ANM1B_XENLA;
DR   Q54EF2, ANM1_DICDI ;  Q99873, ANM1_HUMAN ;  Q9JIF0, ANM1_MOUSE ;
DR   Q63009, ANM1_RAT   ;  Q28F07, ANM1_XENTR ;  Q54HI0, ANM2_DICDI ;
DR   P55345, ANM2_HUMAN ;  Q9R144, ANM2_MOUSE ;  D9IVE5, ANM2_XENLA ;
DR   B3DLB3, ANM2_XENTR ;  A7YW45, ANM5_BOVIN ;  P46580, ANM5_CAEEL ;
DR   Q54KI3, ANM5_DICDI ;  O14744, ANM5_HUMAN ;  Q4R5M3, ANM5_MACFA ;
DR   Q8CIG8, ANM5_MOUSE ;  A2X0Q3, ANM5_ORYSI ;  Q6YXZ7, ANM5_ORYSJ ;
DR   Q5R698, ANM5_PONAB ;  Q5E9L5, ANM6_BOVIN ;  Q6NWG4, ANM6_DANRE ;
DR   Q96LA8, ANM6_HUMAN ;  Q6NZB1, ANM6_MOUSE ;  Q68EZ3, ANM6_XENLA ;
DR   B0JYW5, ANM6_XENTR ;  A6QQV6, ANM7_BOVIN ;  Q5ZIB9, ANM7_CHICK ;
DR   Q99MI9, ANM7_CRILO ;  A2AV36, ANM7_DANRE ;  Q9NVM4, ANM7_HUMAN ;
DR   Q922X9, ANM7_MOUSE ;  Q5U4E8, ANM7_RAT   ;  Q6PCI6, ANM7_XENLA ;
DR   Q174R2, CARM1_AEDAE;  Q7Q2B7, CARM1_ANOGA;  B0W3L6, CARM1_CULQU;
DR   Q6DC04, CARM1_DANRE;  B3M1E1, CARM1_DROAN;  B3P4N5, CARM1_DROER;
DR   B4JXV2, CARM1_DROGR;  Q9VH48, CARM1_DROME;  B4KA23, CARM1_DROMO;
DR   B4GZ20, CARM1_DROPE;  Q29B63, CARM1_DROPS;  B4HJC0, CARM1_DROSE;
DR   B4QVW6, CARM1_DROSI;  B4LVS8, CARM1_DROVI;  B4NKI9, CARM1_DROWI;
DR   B4PVH6, CARM1_DROYA;  Q86X55, CARM1_HUMAN;  Q9WVG6, CARM1_MOUSE;
DR   A2YPT7, CARM1_ORYSI;  Q7XI75, CARM1_ORYSJ;  Q4AE70, CARM1_RAT  ;
DR   Q5XK84, CARM1_XENLA;  P38274, HSL7_YEAST ;
//
ID   2.1.1.126
DE   [Myelin basic protein]-arginine N-methyltransferase.
AN   Myelin basic protein methylase.
AN   Protein methylase I.
AN   Protein-arginine N-methyltransferase.
CA   S-adenosyl-L-methionine + [myelin basic protein]-arginine = S-adenosyl-L-
CA   homocysteine + [myelin basic protein]-N(omega)-methyl-arginine.
CC   -!- Forms the N(omega)-monomethyl-, N(omega),N(omega)-dimethyl- and
CC       N(omega),N(omega')-dimethyl-arginine derivatives.
CC   -!- The name protein methylase I is misleading since it has been used for
CC       a number of enzymes with different specificities.
CC   -!- Formerly EC 2.1.1.23.
DR   A6QQV6, ANM7_BOVIN ;  Q5ZIB9, ANM7_CHICK ;  Q99MI9, ANM7_CRILO ;
DR   A2AV36, ANM7_DANRE ;  Q9NVM4, ANM7_HUMAN ;  Q922X9, ANM7_MOUSE ;
DR   Q5U4E8, ANM7_RAT   ;  Q6PCI6, ANM7_XENLA ;
//
ID   2.1.1.127
DE   [Ribulose-bisphosphate carboxylase]-lysine N-methyltransferase.
AN   Ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase.
AN   RuBisCO LSMT.
AN   RuBisCO methyltransferase.
CA   S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine
CA   = S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-
CA   N(6)-methyl-L-lysine.
CC   -!- The enzyme methylates Lys-14 in the large subunits of hexadecameric
CC       higher plant EC 4.1.1.39.
DR   Q9XI84, RBCMT_ARATH;  Q43088, RBCMT_PEA  ;  P94026, RBCMT_TOBAC;
//
ID   2.1.1.128
DE   (RS)-norcoclaurine 6-O-methyltransferase.
CA   S-adenosyl-L-methionine + (RS)-norcoclaurine = S-adenosyl-L-homocysteine
CA   + (RS)-coclaurine.
CC   -!- Norcoclaurine is 6,7-dihydroxy-1-((4-hydroxyphenyl)methyl)-1,2,3,4-
CC       tetrahydroisoquinoline.
CC   -!- The enzyme will also catalyze the 6-O-methylation of (RS)-
CC       norlaudanosoline to form 6-O-methyl-norlaudanosoline, but this
CC       alkaloid has not been found to occur in plants.
DR   Q9LEL6, 6OMT_COPJA ;
//
ID   2.1.1.129
DE   Inositol 4-methyltransferase.
AN   Myo-inositol 4-O-methyltransferase.
AN   Myo-inositol 6-O-methyltransferase.
AN   S-adenosyl-L-methionine:myo-inositol 4-O-methyltransferase.
CA   S-adenosyl-L-methionine + myo-inositol = S-adenosyl-L-homocysteine +
CA   1D-4-O-methyl-myo-inositol.
CC   -!- The enzyme from Vigna umbellata is highly specific for S-adenosyl-L-
CC       methionine.
CC   -!- The enzyme also methylates 1L-1,2,4/3,5-cyclohexanepentol, 2,4,6/3,5-
CC       pentahydroxycyclohexanone, D,L-2,3,4,6/5-pentacyclohexanone and
CC       2,2'-anhydro-2-C-hydroxymethyl-myo-inositol, but at lower rates than
CC       that of myo-inositol.
CC   -!- Formerly EC 2.1.1.134.
DR   P45986, IMT1_MESCR ;
//
ID   2.1.1.130
DE   Precorrin-2 C(20)-methyltransferase.
AN   Precorrin-2 C20-methyltransferase.
AN   S-adenosyl-L-methionine--precorrin-2 methyltransferase.
CA   S-adenosyl-L-methionine + precorrin-2 = S-adenosyl-L-homocysteine +
CA   precorrin-3A.
DR   P66878, COBIJ_MYCBO;  P66877, COBIJ_MYCTU;  Q9HZU3, COBI_PSEAE ;
DR   P21639, COBI_PSEDE ;
//
ID   2.1.1.131
DE   Precorrin-3B C(17)-methyltransferase.
AN   Precorrin-3 methylase.
AN   Precorrin-3 methyltransferase.
AN   Precorrin-3B C17-methyltransferase.
CA   S-adenosyl-L-methionine + precorrin-3B = S-adenosyl-L-homocysteine +
CA   precorrin-4.
CC   -!- In the aerobic cobalamin biosythesis pathway, four enzymes are
CC       involved in the conversion of precorrin-3A to precorrin-6A.
CC   -!- The first of the four steps is carried out by EC 1.14.13.83 (CobG),
CC       yielding precorrin-3B as the product.
CC   -!- This is followed by three methylation reactions, which introduce a
CC       methyl group at C-17 (CobJ; EC 2.1.1.131), C-11 (CobM; 2.1.1.133) and
CC       C-1 (CobF; EC 2.1.1.152) of the macrocycle, giving rise to precorrin-
CC       4, precorrin-5 and precorrin-6A, respectively.
DR   P66878, COBIJ_MYCBO;  P66877, COBIJ_MYCTU;  P21640, COBJ_PSEDE ;
//
ID   2.1.1.132
DE   Precorrin-6Y C(5,15)-methyltransferase (decarboxylating).
AN   Precorrin-6 methyltransferase.
AN   Precorrin-6Y C5,15-methyltransferase (decarboxylating).
AN   Precorrin-6Y methylase.
CA   2 S-adenosyl-L-methionine + precorrin-6Y = 2 S-adenosyl-L-homocysteine +
CA   precorrin-8X + CO(2).
CC   -!- The enzyme from Pseudomonas denitrificans has S-adenosyl-L-
CC       methionine-dependent methyltransferase and decarboxylase activities.
DR   Q10671, COBL_MYCTU ;  Q9HZU0, COBL_PSEAE ;  P21921, COBL_PSEDE ;
//
ID   2.1.1.133
DE   Precorrin-4 C(11)-methyltransferase.
AN   Precorrin-3 methylase.
AN   Precorrin-4 C11-methyltransferase.
CA   S-adenosyl-L-methionine + precorrin-4 = S-adenosyl-L-homocysteine +
CA   precorrin-5.
CC   -!- In the aerobic cobalamin biosythesis pathway, four enzymes are
CC       involved in the conversion of precorrin-3A to precorrin-6A.
CC   -!- The first of the four steps is carried out by EC 1.14.13.83 (CobG),
CC       yielding precorrin-3B as the product.
CC   -!- This is followed by three methylation reactions, which introduce a
CC       methyl group at C-17 (CobJ; EC 2.1.1.131), C-11 (CobM; 2.1.1.133) and
CC       C-1 (CobF; EC 2.1.1.152) of the macrocycle, giving rise to precorrin-
CC       4, precorrin-5 and precorrin-6A, respectively.
DR   Q10672, COBM_MYCTU ;  Q9HZP9, COBM_PSEAE ;  P21922, COBM_PSEDE ;
DR   O68100, COBM_RHOCB ;  Q53138, COBM_RHOER ;
//
ID   2.1.1.134
DE   Transferred entry: 2.1.1.129.
//
ID   2.1.1.135
DE   Transferred entry: 1.16.1.8.
//
ID   2.1.1.136
DE   Chlorophenol O-methyltransferase.
AN   Halogenated phenol O-methyltransferase.
AN   Trichlorophenol O-methyltransferase.
CA   S-adenosyl-L-methionine + trichlorophenol = S-adenosyl-L-homocysteine +
CA   trichloroanisole.
CC   -!- The enzyme from Trichoderma virgatum, when cultured in the presence
CC       of halogenated phenol, also acts on a range of mono-, di- and
CC       trichlorophenols.
//
ID   2.1.1.137
DE   Arsenite methyltransferase.
AN   Methylarsonite methyltransferase.
AN   S-adenosyl-L-methionine:arsenic(III) methyltransferase.
AN   S-adenosyl-L-methionine:methylarsonite As-methyltransferase.
CA   (1) S-adenosyl-L-methionine + arsenite = S-adenosyl-L-homocysteine +
CA   methylarsonate.
CA   (2) S-adenosyl-L-methionine + methylarsonite = S-adenosyl-L-homocysteine
CA   + dimethylarsinate.
CC   -!- An enzyme of the biotransformation pathway that forms
CC       dimethylarsinate from inorganic arsenite and arsenate.
CC   -!- It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which
CC       is reduced by EC 1.20.4.2 to methylarsonite, Me-As(OH)(2).
CC   -!- Methylarsonite is also a substrate for this enzyme which converts it
CC       into the much less toxic compound dimethylarsinate (cacodylate),
CC       Me(2)As(O)-OH.
DR   Q9HBK9, AS3MT_HUMAN;  Q91WU5, AS3MT_MOUSE;  Q8VHT6, AS3MT_RAT  ;
//
ID   2.1.1.138
DE   Deleted entry.
//
ID   2.1.1.139
DE   3'-demethylstaurosporine O-methyltransferase.
AN   3'-demethoxy-3'-hydroxystaurosporine O-methyltransferase.
AN   Staurosporine synthase.
CA   S-adenosyl-L-methionine + 3'-demethylstaurosporine = S-adenosyl-L-
CA   homocysteine + staurosporine.
CC   -!- Catalyzes the final step in the biosynthesis of staurosporine,
CC       an alkaloidal antibiotic that is a potent inhibitor of protein
CC       kinases, especially protein kinase C.
//
ID   2.1.1.140
DE   (S)-coclaurine-N-methyltransferase.
CA   S-adenosyl-L-methionine + (S)-coclaurine = S-adenosyl-L-homocysteine +
CA   (S)-N-methylcoclaurine.
CC   -!- The enzyme is specific for the (S)-isomer of coclaurine.
CC   -!- Norcoclaurine can also act as an acceptor.
DR   Q5C9L6, CNMT_THLFG ;
//
ID   2.1.1.141
DE   Jasmonate O-methyltransferase.
AN   Jasmonic acid carboxyl methyltransferase.
CA   S-adenosyl-L-methionine + jasmonate = S-adenosyl-L-homocysteine + methyl
CA   jasmonate.
CC   -!- 9,10-dihydrojasmonic acid is a poor substrate for the enzyme.
CC   -!- The enzyme does not convert 12-oxo-phytodienoic acid (a precursor of
CC       jasmonic acid), salicylic acid, benzoic acid, linolenic acid or
CC       cinnamic acid into their corresponding methyl esters.
CC   -!- Enzyme activity is inhibited by the presence of divalent cations,
CC       e.g., Ca(2+), Cu(2+), Mg(2+) and Zn(2+).
DR   Q9AR07, JMT_ARATH  ;  Q9SBK6, JMT_BRARP  ;
//
ID   2.1.1.142
DE   Cycloartenol 24-C-methyltransferase.
AN   Sterol C-methyltransferase.
CA   S-adenosyl-L-methionine + cycloartenol = S-adenosyl-L-homocysteine +
CA   (24R)-24-methylcycloart-25-en-3-beta-ol.
CC   -!- S-adenosyl-L-methionine methylates the Si face of the 24(25)-double
CC       bond with elimination of a hydrogen atom from the pro-Z methyl group
CC       at C-25.
//
ID   2.1.1.143
DE   24-methylenesterol C-methyltransferase.
AN   24-methylenelophenol C-24(1)-methyltransferase.
AN   SMT(2).
CA   S-adenosyl-L-methionine + 24-methylenelophenol = S-adenosyl-L-
CA   homocysteine + (Z)-24-ethylidenelophenol.
CC   -!- This is the second methylation step of plant sterol biosynthesis (cf.
CC       EC 2.1.1.142).
DR   Q39227, SMT2_ARATH ;  O82427, SMT2_ORYSJ ;  Q94JS4, SMT3B_ARATH;
//
ID   2.1.1.144
DE   Trans-aconitate 2-methyltransferase.
CA   S-adenosyl-L-methionine + trans-aconitate = S-adenosyl-L-homocysteine +
CA   (E)-3-(methoxycarbonyl)pent-2-enedioate.
CC   -!- Also catalyzes the formation of the methyl monoester of cis-
CC       aconitate, isocitrate and citrate, but more slowly.
CC   -!- While the enzyme from Escherichia coli forms (E)-3-(methoxycarbonyl)-
CC       pent-2-enedioate as the product, that from Saccharomyces cerevisiae
CC       forms (E)-2-(methoxycarbonylmethyl)butenedioate and is therefore
CC       classified as a separate enzyme (cf. EC 2.1.1.145).
DR   A1TP97, TAM_ACIAC  ;  B9MBN9, TAM_ACIET  ;  A1W9K6, TAM_ACISJ  ;
DR   B9JBE6, TAM_AGRRK  ;  Q8UH15, TAM_AGRT5  ;  A1K8U5, TAM_AZOSB  ;
DR   A9M6C1, TAM_BRUC2  ;  Q8YI91, TAM_BRUME  ;  A5VRJ7, TAM_BRUO2  ;
DR   B0CHP1, TAM_BRUSI  ;  Q8FZM5, TAM_BRUSU  ;  Q9RX93, TAM_DEIRA  ;
DR   A9BVK1, TAM_DELAS  ;  A7ZLX5, TAM_ECO24  ;  B7URP6, TAM_ECO27  ;
DR   B7MMY3, TAM_ECO45  ;  B7L7L9, TAM_ECO55  ;  Q8XAZ2, TAM_ECO57  ;
DR   B5Z1X6, TAM_ECO5E  ;  B7NIJ1, TAM_ECO7I  ;  B7LZC1, TAM_ECO8A  ;
DR   C4ZWT6, TAM_ECOBW  ;  B1XEA7, TAM_ECODH  ;  A8A072, TAM_ECOHS  ;
DR   A1AB99, TAM_ECOK1  ;  Q0THR9, TAM_ECOL5  ;  Q8FHF2, TAM_ECOL6  ;
DR   B1IRU1, TAM_ECOLC  ;  P76145, TAM_ECOLI  ;  B7N4U4, TAM_ECOLU  ;
DR   B6IAS2, TAM_ECOSE  ;  B1LF96, TAM_ECOSM  ;  Q1RBP8, TAM_ECOUT  ;
DR   A4WAG4, TAM_ENT38  ;  B7LRD2, TAM_ESCF3  ;  B5XQT8, TAM_KLEP3  ;
DR   B8ISV4, TAM_METNO  ;  B1LXF6, TAM_METRJ  ;  B0UPF4, TAM_METS4  ;
DR   A0QM44, TAM_MYCA1  ;  P66886, TAM_MYCBO  ;  A1KFB7, TAM_MYCBP  ;
DR   C1AJX2, TAM_MYCBT  ;  A4T0W0, TAM_MYCGI  ;  B2HNX5, TAM_MYCMM  ;
DR   A3PTG0, TAM_MYCSJ  ;  A1U9V4, TAM_MYCSK  ;  Q1BF27, TAM_MYCSS  ;
DR   A5TZ21, TAM_MYCTA  ;  P66885, TAM_MYCTU  ;  A0PN72, TAM_MYCUA  ;
DR   A1T273, TAM_MYCVP  ;  Q1QJC0, TAM_NITHX  ;  Q3SPQ7, TAM_NITWN  ;
DR   A6WZN1, TAM_OCHA4  ;  B6JIA0, TAM_OLICO  ;  A6V4P3, TAM_PSEA7  ;
DR   Q02N15, TAM_PSEAB  ;  Q9I0S1, TAM_PSEAE  ;  B3PTJ5, TAM_RHIE6  ;
DR   Q2KAZ5, TAM_RHIEC  ;  Q98K73, TAM_RHILO  ;  B5ZUL2, TAM_RHILW  ;
DR   Q92RC5, TAM_RHIME  ;  C3M8G8, TAM_RHISN  ;  Q2IYT0, TAM_RHOP2  ;
DR   Q07PZ6, TAM_RHOP5  ;  Q6N3T8, TAM_RHOPA  ;  Q216J6, TAM_RHOPB  ;
DR   Q133R5, TAM_RHOPS  ;  B3QFV9, TAM_RHOPT  ;  Q0SED2, TAM_RHOSR  ;
DR   Q32G05, TAM_SHIDS  ;  Q0T4L2, TAM_SHIF8  ;  Q83RE0, TAM_SHIFL  ;
DR   A6U707, TAM_SINMW  ;  Q82HD9, TAM_STRAW  ;  Q9K3T2, TAM_STRCO  ;
DR   C5CSI6, TAM_VARPS  ;  A1JU33, TAM_YERE8  ;  A7FGU8, TAM_YERP3  ;
DR   Q1C6F5, TAM_YERPA  ;  B2K7X9, TAM_YERPB  ;  Q8ZDP7, TAM_YERPE  ;
DR   A9R6H5, TAM_YERPG  ;  Q1CHU7, TAM_YERPN  ;  A4TLZ2, TAM_YERPP  ;
DR   Q669E2, TAM_YERPS  ;  B1JHA2, TAM_YERPY  ;
//
ID   2.1.1.145
DE   Trans-aconitate 3-methyltransferase.
CA   S-adenosyl-L-methionine + trans-aconitate = S-adenosyl-L-homocysteine +
CA   (E)-2-(methoxycarbonylmethyl)butenedioate.
CC   -!- Also catalyzes the formation of the methyl monoester of cis-
CC       aconitate, isocitrate and citrate, but more slowly.
CC   -!- While the enzyme from Saccharomyces cerevisiae forms (E)-2-
CC       (methoxycarbonylmethyl)butenedioate as the product, that from
CC       Escherichia coli forms (E)-3-(methoxycarbonyl)-pent-2-enedioate and
CC       is therefore classified as a separate enzyme (cf. EC 2.1.1.144).
DR   A6ZRD1, TMT1_YEAS7 ;  P32643, TMT1_YEAST ;
//
ID   2.1.1.146
DE   (Iso)eugenol O-methyltransferase.
CA   S-adenosyl-L-methionine + isoeugenol = S-adenosyl-L-homocysteine +
CA   isomethyleugenol.
CC   -!- Acts on eugenol and chavicol as well as isoeugenol.
DR   Q93WU3, CVMT1_OCIBA;  Q93WU2, EOMT1_OCIBA;  O04385, IEMT_CLABR ;
DR   A8QW52, OMT1_SORBI ;
//
ID   2.1.1.147
DE   Corydaline synthase.
CA   S-adenosyl-L-methionine + palmatine + 2 NADPH = S-adenosyl-L-homocysteine
CA   + corydaline + 2 NADP(+).
CC   -!- Also acts on 7,8-dihydropalmatine.
//
ID   2.1.1.148
DE   Thymidylate synthase (FAD).
AN   FDTS.
AN   Flavin dependent thymidylate synthase.
CA   5,10-methylenetetrahydrofolate + dUMP + NADPH = dTMP + tetrahydrofolate +
CA   NADP(+).
CC   -!- Contains FAD.
CC   -!- All thymidylate synthases catalyze a reductive methylation involving
CC       the transfer of the methylene group of 5,10-methylenetetrahydrofolate
CC       to the C5-position of dUMP and a two electron reduction of the
CC       methylene group to a methyl group.
CC   -!- Unlike the classical thymidylate synthase, ThyA (EC 2.1.1.45), which
CC       uses folate as both a 1-carbon donor and a source of reducing
CC       equivalents, this enzyme uses a flavin coenzyme as a source of
CC       reducing equivalents, which are derived from NADPH.
DR   P15808, THY1_DICDI ;  Q9YA75, THYX_AERPE ;  Q5PBM3, THYX_ANAMM ;
DR   O66883, THYX_AQUAE ;  O50965, THYX_BORBU ;  O64238, THYX_BPMD2 ;
DR   Q05259, THYX_BPML5 ;  Q9ZX92, THYX_BPPHC ;  Q9PJ85, THYX_CAMJE ;
DR   Q5HXD2, THYX_CAMJR ;  Q8XHQ7, THYX_CLOPE ;  Q890M6, THYX_CLOTE ;
DR   C3PH05, THYX_CORA7 ;  Q6NGP3, THYX_CORDI ;  Q8RQM9, THYX_COREF ;
DR   P40111, THYX_CORGL ;  Q729U4, THYX_DESVH ;  Q5FG35, THYX_EHRRG ;
DR   Q5HAK2, THYX_EHRRW ;  Q748A9, THYX_GEOSL ;  Q5FR18, THYX_GLUOX ;
DR   Q5V325, THYX_HALMA ;  Q9HQ52, THYX_HALSA ;  Q9ZJ93, THYX_HELPJ ;
DR   O26061, THYX_HELPY ;  C5CHB8, THYX_KOSOT ;  A0QIT4, THYX_MYCA1 ;
DR   B1MD42, THYX_MYCA9 ;  P66931, THYX_MYCBO ;  A1KM95, THYX_MYCBP ;
DR   C1AFL6, THYX_MYCBT ;  A4TCJ4, THYX_MYCGI ;  B8ZRR4, THYX_MYCLB ;
DR   Q9CBW3, THYX_MYCLE ;  B2HKZ0, THYX_MYCMM ;  Q73VZ6, THYX_MYCPA ;
DR   A0QVT0, THYX_MYCS2 ;  A3PYB1, THYX_MYCSJ ;  A1UEV1, THYX_MYCSK ;
DR   Q1BA61, THYX_MYCSS ;  A5U6A7, THYX_MYCTA ;  P66930, THYX_MYCTU ;
DR   A1T7Q0, THYX_MYCVP ;  O41156, THYX_PBCV1 ;  Q9UZ51, THYX_PYRAB ;
DR   Q8ZWD6, THYX_PYRAE ;  Q8U3C9, THYX_PYRFU ;  O58498, THYX_PYRHO ;
DR   Q5JI17, THYX_PYRKO ;  Q1RJV8, THYX_RICBR ;  Q92IL5, THYX_RICCN ;
DR   Q4UM78, THYX_RICFE ;  Q9ZDM6, THYX_RICPR ;  Q68X70, THYX_RICTY ;
DR   Q5LTY7, THYX_SILPO ;  Q82K86, THYX_STRAW ;  O86840, THYX_STRCO ;
DR   Q4J6F2, THYX_SULAC ;  Q980H6, THYX_SULSO ;  Q96YF6, THYX_SULTO ;
DR   P73053, THYX_SYNY3 ;  B7IF44, THYX_THEAB ;  A8F7Q7, THYX_THELT ;
DR   A6LP90, THYX_THEM4 ;  Q9WYT0, THYX_THEMA ;  B9KBK3, THYX_THENN ;
DR   B6YTN5, THYX_THEON ;  A5IJX2, THYX_THEP1 ;  B1L944, THYX_THESQ ;
DR   Q72JN9, THYX_THET2 ;  Q5SJB8, THYX_THET8 ;  Q73QY2, THYX_TREDE ;
DR   O83971, THYX_TREPA ;  Q83HF9, THYX_TROW8 ;  Q83MS7, THYX_TROWT ;
DR   Q73FX5, THYX_WOLPM ;  Q7MQK8, THYX_WOLSU ;
//
ID   2.1.1.149
DE   Myricetin O-methyltransferase.
AN   CrCOMT2.
AN   Flavonoid 3',5'-O-dimethyltransferase.
CA   2 S-adenosyl-L-methionine + myricetin = 2 S-adenosyl-L-homocysteine +
CA   syringetin.
CC   -!- The enzyme from Catharanthus roseus (Madagascar periwinkle) is
CC       unusual as it carries out two methylations of the same substrate.
CC   -!- Also catalyzes the methylation of dihydromyricetin.
DR   Q8GSN1, MOMT_CATRO ;
//
ID   2.1.1.150
DE   Isoflavone 7-O-methyltransferase.
CA   S-adenosyl-L-methionine + a 7-hydroxyisoflavone = S-adenosyl-L-
CA   homocysteine + a 7-methoxyisoflavone.
CC   -!- The enzyme from alfalfa can methylate daidzein, genistein and
CC       6,7,4'-trihydroxyisoflavone but not flavones or flavanones.
DR   O22308, 7OMT6_MEDSA;  O24529, 7OMT8_MEDSA;  O22309, 7OMT9_MEDSA;
DR   Q84KK5, D7OMT_GLYEC;
//
ID   2.1.1.151
DE   Cobalt-factor II C(20)-methyltransferase.
AN   Cobalt-precorrin-2 C(20)-methyltransferase.
CA   S-adenosyl-L-methionine + cobalt-factor II = S-adenosyl-L-homocysteine +
CA   cobalt-factor III.
CC   -!- Involved in the anaerobic biosynthesis of vitamin B12.
DR   Q58181, CBIL_METJA ;  Q05593, CBIL_SALTY ;
//
ID   2.1.1.152
DE   Precorrin-6A synthase (deacetylating).
AN   Precorrin-6X synthase (deacetylating).
CA   S-adenosyl-L-methionine + precorrin-5 + H(2)O = S-adenosyl-L-homocysteine
CA   + precorrin-6A + acetate.
CC   -!- In the aerobic cobalamin biosythesis pathway, four enzymes are
CC       involved in the conversion of precorrin-3A to precorrin-6A.
CC   -!- The first of the four steps is carried out by EC 1.14.13.83 (CobG),
CC       yielding precorrin-3B as the product.
CC   -!- This is followed by three methylation reactions, which introduce a
CC       methyl group at C-17 (CobJ; EC 2.1.1.131), C-11 (CobM; 2.1.1.133) and
CC       C-1 (CobF; EC 2.1.1.152) of the macrocycle, giving rise to precorrin-
CC       4, precorrin-5 and precorrin-6A, respectively.
DR   P21636, COBF_PSEDE ;
//
ID   2.1.1.153
DE   Vitexin 2''-O-rhamnoside 7-O-methyltransferase.
CA   S-adenosyl-L-methionine + vitexin 2''-O-beta-L-rhamnoside = S-adenosyl-L-
CA   homocysteine + 7-O-methylvitexin 2''-O-beta-L-rhamnoside.
CC   -!- The flavonoids vitexin and isovitexin 2''-O-arabinoside do not act as
CC       substrates for the enzyme from oats (Avena sativa).
//
ID   2.1.1.154
DE   Isoliquiritigenin 2'-O-methyltransferase.
AN   Chalcone OMT.
AN   CHMT.
CA   S-adenosyl-L-methionine + isoliquiritigenin = S-adenosyl-L-homocysteine +
CA   2'-O-methylisoliquiritigenin.
CC   -!- Not identical to EC 2.1.1.65.
CC   -!- While EC 2.1.1.154 can use licodione as a substrate, EC 2.1.1.65
CC       cannot use isoliquiritigenin as a substrate.
DR   P93324, CHOMT_MEDSA;
//
ID   2.1.1.155
DE   Kaempferol 4'-O-methyltransferase.
AN   F 4'-OMT.
AN   S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase.
CA   S-adenosyl-L-methionine + kaempferol = S-adenosyl-L-homocysteine +
CA   kaempferide.
CC   -!- The enzyme acts on the hydroxy group in the 4'-position of some
CC       flavones, flavanones and isoflavones.
CC   -!- Kaempferol, apigenin and kaempferol triglucoside are substrates,
CC       as is genistein, which reacts more slowly.
CC   -!- Compounds with an hydroxy group in the 3' and 4' positions, such as
CC       quercetin and eriodictyol, do not act as substrates.
CC   -!- Similar to EC 2.1.1.75 and EC 2.1.1.83.
//
ID   2.1.1.156
DE   Glycine/sarcosine N-methyltransferase.
AN   Glycine sarcosine N-methyltransferase.
AN   Glycine-sarcosine methyltransferase.
AN   GMT.
AN   GSMT.
CA   (1) S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine +
CA   sarcosine.
CA   (2) S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine +
CA   N,N-dimethylglycine.
CC   -!- Cells of the oxygen-evolving halotolerant cyanobacterium Aphanocthece
CC       halophytica synthesize betaine from glycine by a three-step
CC       methylation process.
CC   -!- This is the first enzyme and it leads to the formation of either
CC       sarcosine or N,N-dimethylglycine, which is further methylated to
CC       yield betaine (N,N,N-trimethylglycine) by the action of EC 2.1.1.157.
CC   -!- Differs from EC 2.1.1.20, as it can further methylate the product of
CC       the first reaction.
CC   -!- Acetate, dimethylglycine and S-adenosyl-L-homocysteine can inhibit
CC       the reaction.
DR   Q83WC4, GSMT_APHHA ;
//
ID   2.1.1.157
DE   Sarcosine/dimethylglycine N-methyltransferase.
AN   ApDMT.
AN   Sarcosine dimethylglycine N-methyltransferase.
AN   Sarcosine-dimethylglycine methyltransferase.
AN   SDMT.
CA   (1) S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine +
CA   N,N-dimethylglycine.
CA   (2) S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-
CA   homocysteine + betaine.
CC   -!- Cells of the oxygen-evolving halotolerant cyanobacterium Aphanocthece
CC       halophytica synthesize betaine from glycine by a three-step
CC       methylation process.
CC   -!- The first enzyme, EC 2.1.1.156, leads to the formation of either
CC       sarcosine or N,N-dimethylglycine, which is further methylated to
CC       yield betaine (N,N,N-trimethylglycine) by the action of this enzyme.
CC   -!- Both of these enzymes can catalyze the formation of
CC       N,N-dimethylglycine from sarcosine.
CC   -!- The reactions are strongly inhibited by S-adenosyl-L-homocysteine.
DR   Q83WC3, DMT_APHHA  ;
//
ID   2.1.1.158
DE   7-methylxanthosine synthase.
AN   Xanthosine methyltransferase.
AN   XMT.
AN   XRS1.
CA   S-adenosyl-L-methionine + xanthosine = S-adenosyl-L-homocysteine +
CA   7-methylxanthosine.
CC   -!- The enzyme is specific for xanthosine, as XMP and xanthine cannot act
CC       as substrates.
CC   -!- The enzyme does not have N(1)- or N(3)- methylation activity.
CC   -!- This is the first methylation step in the production of caffeine.
DR   Q9AVK0, XMT1_COFAR ;  A4GE69, XMT1_COFCA ;
//
ID   2.1.1.159
DE   Theobromine synthase.
AN   Monomethylxanthine methyltransferase.
AN   MXMT.
CA   S-adenosyl-L-methionine + 7-methylxanthine = S-adenosyl-L-homocysteine +
CA   3,7-dimethylxanthine.
CC   -!- Can also catalyze the conversion of paraxanthine into caffeine,
CC       although the paraxanthine pathway is considered to be a minor pathway
CC       for caffeine biosynthesis.
CC   -!- This is the third enzyme in the caffeine biosynthesis pathway.
DR   Q8H0G0, CTS2_COFAR ;  Q9AVJ9, MXMT1_COFAR;  Q84PP7, MXMT2_COFAR;
//
ID   2.1.1.160
DE   Caffeine synthase.
AN   3N-methyltransferase.
AN   Dimethylxanthine methyltransferase.
CA   (1) S-adenosyl-L-methionine + 3,7-dimethylxanthine = S-adenosyl-L-
CA   homocysteine + 1,3,7-trimethylxanthine.
CA   (2) S-adenosyl-L-methionine + 1,7-dimethylxanthine = S-adenosyl-L-
CA   homocysteine + 1,3,7-trimethylxanthine.
CA   (3) S-adenosyl-L-methionine + 7-methylxanthine = S-adenosyl-L-
CA   homocysteine + 3,7-dimethylxanthine.
CC   -!- Paraxanthine is the best substrate for this enzyme but the
CC       paraxanthine pathway is considered to be a minor pathway for caffeine
CC       biosynthesis.
DR   Q8H0D3, CCS1_COFAR ;  Q8H0D2, DXMT1_COFAR;  A4GE70, DXMT1_COFCA;
DR   Q9FZN8, TCS1_CAMSI ;  Q68CM3, TCS2_CAMSI ;
//
ID   2.1.1.161
DE   Dimethylglycine N-methyltransferase.
AN   DMT.
CA   S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine
CA   + betaine.
CC   -!- This enzyme, from the marine cyanobacterium Synechococcus sp. strain
CC       WH8102, differs from EC 2.1.1.157 in that it cannot use sarcosine as
CC       an alternative substrate.
CC   -!- Betaine is a 'compatible solute' that enables cyanobacteria to cope
CC       with osmotic stress by maintaining a positive cellular turgor.
//
ID   2.1.1.162
DE   Glycine/sarcosine/dimethylglycine N-methyltransferase.
AN   Glycine sarcosine dimethylglycine N-methyltransferase.
AN   GSDMT.
CA   (1) S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine +
CA   sarcosine.
CA   (2) S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine +
CA   N,N-dimethylglycine.
CA   (3) S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-
CA   homocysteine + betaine.
CC   -!- Unlike EC 2.1.1.156, EC 2.1.1.157 and EC 2.1.1.161, this enzyme, from
CC       the halophilic methanoarchaeon Methanohalophilus portucalensis,
CC       can methylate glycine and all of its intermediates to form the
CC       compatible solute betaine.
//
ID   2.1.1.163
DE   Demethylmenaquinone methyltransferase.
AN   2-demethylmenaquinone methyltransferase.
AN   2-heptaprenyl-1,4-naphthoquinone methyltransferase.
AN   Demethylmenaquinone C-methylase.
CA   A demethylmenaquinone + S-adenosyl-L-methionine = a menaquinol +
CA   S-adenosyl-L-homocysteine.
CC   -!- The enzyme catalyzes the last step in menaquinone biosynthesis.
CC   -!- It is able to accept substrates with varying polyprenyl side chain
CC       length (the chain length is determined by polyprenyl diphosphate
CC       synthase).
CC   -!- The enzyme from Escherichia coli also catalyzes the conversion of
CC       2-methoxy-6-octaprenyl-1,4-benzoquinone to 5-methoxy-2-methyl-3-
CC       octaprenyl-1,4-benzoquinone during the biosynthesis of ubiquinone.
CC   -!- The enzyme probably acts on menaquinol rather than menaquinone.
PR   PROSITE; PDOC00911;
DR   A5FZ96, UBIE_ACICJ ;  B9J7S8, UBIE_AGRRK ;  Q8UIH5, UBIE_AGRT5 ;
DR   B9JZF4, UBIE_AGRVS ;  Q3MD91, UBIE_ANAVT ;  B7GHP8, UBIE_ANOFW ;
DR   A1R990, UBIE_ARTAT ;  C1DHS2, UBIE_AZOVD ;  A7Z627, UBIE_BACA2 ;
DR   C3P5A0, UBIE_BACAA ;  C3L8S6, UBIE_BACAC ;  Q81SW0, UBIE_BACAN ;
DR   B7JGZ8, UBIE_BACC0 ;  Q73AY2, UBIE_BACC1 ;  B7IP91, UBIE_BACC2 ;
DR   C1EN10, UBIE_BACC3 ;  B7HHR7, UBIE_BACC4 ;  B7HL23, UBIE_BACC7 ;
DR   A7GN50, UBIE_BACCN ;  B9IVN5, UBIE_BACCQ ;  Q81FQ6, UBIE_BACCR ;
DR   Q63DL9, UBIE_BACCZ ;  Q5LH04, UBIE_BACFN ;  Q64XV8, UBIE_BACFR ;
DR   Q9KCC4, UBIE_BACHD ;  Q6HL42, UBIE_BACHK ;  Q65I24, UBIE_BACLD ;
DR   A8FEK9, UBIE_BACP2 ;  P94298, UBIE_BACPE ;  Q5WGT4, UBIE_BACSK ;
DR   P31113, UBIE_BACSU ;  Q8A005, UBIE_BACTN ;  A6L3D5, UBIE_BACV8 ;
DR   A9VMC2, UBIE_BACWK ;  A1UUE1, UBIE_BARBK ;  Q6G577, UBIE_BARHE ;
DR   Q6G1I2, UBIE_BARQU ;  A9ILA7, UBIE_BART1 ;  Q6MHQ3, UBIE_BDEBA ;
DR   C5C0T0, UBIE_BEUC1 ;  Q7VRJ1, UBIE_BLOFL ;  Q491V7, UBIE_BLOPB ;
DR   Q2KUG1, UBIE_BORA1 ;  Q7WF12, UBIE_BORBR ;  Q7W3N6, UBIE_BORPA ;
DR   Q7W0H1, UBIE_BORPE ;  Q89WD0, UBIE_BRAJA ;  A5E888, UBIE_BRASB ;
DR   A4YJH0, UBIE_BRASO ;  B2SC50, UBIE_BRUA1 ;  Q2YJM4, UBIE_BRUA2 ;
DR   Q576Q0, UBIE_BRUAB ;  A9MCZ2, UBIE_BRUC2 ;  C0RMK3, UBIE_BRUMB ;
DR   Q8YDE4, UBIE_BRUME ;  A9WW74, UBIE_BRUSI ;  Q8FUZ3, UBIE_BRUSU ;
DR   B1YWF9, UBIE_BURA4 ;  Q1BTN4, UBIE_BURCA ;  B1JYJ6, UBIE_BURCC ;
DR   A0KAF5, UBIE_BURCH ;  B4EBC4, UBIE_BURCJ ;  Q0BBY4, UBIE_BURCM ;
DR   A9AFC0, UBIE_BURM1 ;  A3MNT8, UBIE_BURM7 ;  A2S8L1, UBIE_BURM9 ;
DR   Q62MP4, UBIE_BURMA ;  A1V753, UBIE_BURMS ;  A3NRJ4, UBIE_BURP0 ;
DR   Q3JVZ6, UBIE_BURP1 ;  A3N5U8, UBIE_BURP6 ;  B2JCU8, UBIE_BURP8 ;
DR   B2SX35, UBIE_BURPP ;  Q63XA0, UBIE_BURPS ;  Q39D13, UBIE_BURS3 ;
DR   Q2T139, UBIE_BURTA ;  A4JHS6, UBIE_BURVG ;  Q145P0, UBIE_BURXL ;
DR   A8FKB3, UBIE_CAMJ8 ;  Q9PIH5, UBIE_CAMJE ;  A1VY43, UBIE_CAMJJ ;
DR   Q5HWE7, UBIE_CAMJR ;  B8GVY5, UBIE_CAUCN ;  Q9A258, UBIE_CAUCR ;
DR   B0T7D0, UBIE_CAUSK ;  B3PH48, UBIE_CELJU ;  Q81ZV1, UBIE_CHLCV ;
DR   Q253I8, UBIE_CHLFF ;  Q9PJW4, UBIE_CHLMU ;  B3QLI9, UBIE_CHLP8 ;
DR   Q9K2B6, UBIE_CHLPN ;  B0B800, UBIE_CHLT2 ;  Q3KLS2, UBIE_CHLTA ;
DR   B0BC65, UBIE_CHLTB ;  Q8KF69, UBIE_CHLTE ;  O84435, UBIE_CHLTR ;
DR   Q7NZD3, UBIE_CHRVO ;  A8ACY2, UBIE_CITK8 ;  B0RCZ0, UBIE_CLAMS ;
DR   C3PKL1, UBIE_CORA7 ;  Q8FSB3, UBIE_COREF ;  A4QBE5, UBIE_CORGB ;
DR   Q8NT39, UBIE_CORGL ;  C4LL93, UBIE_CORK4 ;  B1VEN4, UBIE_CORU7 ;
DR   B6J676, UBIE_COXB1 ;  B6J3P6, UBIE_COXB2 ;  A9KD75, UBIE_COXBN ;
DR   A9N9F4, UBIE_COXBR ;  Q83A90, UBIE_COXBU ;  Q0KEH6, UBIE_CUPNH ;
DR   Q475X0, UBIE_CUPPJ ;  B2AH07, UBIE_CUPTR ;  Q9RRT0, UBIE_DEIRA ;
DR   Q24W96, UBIE_DESHY ;  Q6ANL3, UBIE_DESPS ;  A8LNK7, UBIE_DINSH ;
DR   A7ZU40, UBIE_ECO24 ;  B7UNG3, UBIE_ECO27 ;  B7MHC0, UBIE_ECO45 ;
DR   B7L996, UBIE_ECO55 ;  P0A888, UBIE_ECO57 ;  B5YY82, UBIE_ECO5E ;
DR   B7NV33, UBIE_ECO7I ;  B7N2E1, UBIE_ECO81 ;  B7M638, UBIE_ECO8A ;
DR   C5A009, UBIE_ECOBW ;  B1XAJ7, UBIE_ECODH ;  A8A6U0, UBIE_ECOHS ;
DR   A1AI22, UBIE_ECOK1 ;  Q0TAM1, UBIE_ECOL5 ;  Q8FBJ0, UBIE_ECOL6 ;
DR   B1IW72, UBIE_ECOLC ;  P0A887, UBIE_ECOLI ;  B7NFD6, UBIE_ECOLU ;
DR   B6I4H5, UBIE_ECOSE ;  B1LM21, UBIE_ECOSM ;  Q1R477, UBIE_ECOUT ;
DR   C5BCA4, UBIE_EDWI9 ;  A4WFY5, UBIE_ENT38 ;  A7MQL7, UBIE_ENTS8 ;
DR   Q6DAQ7, UBIE_ERWCT ;  B2VG41, UBIE_ERWT9 ;  B7LU01, UBIE_ESCF3 ;
DR   B0TZP1, UBIE_FRAP2 ;  A8LCA4, UBIE_FRASN ;  Q14GU4, UBIE_FRAT1 ;
DR   A7NAA1, UBIE_FRATF ;  Q2A524, UBIE_FRATH ;  B2SFA2, UBIE_FRATM ;
DR   A0Q549, UBIE_FRATN ;  Q0BNE2, UBIE_FRATO ;  Q5NFE1, UBIE_FRATT ;
DR   A4IXH9, UBIE_FRATW ;  B5EFL1, UBIE_GEOBB ;  Q5KXU0, UBIE_GEOKA ;
DR   O86169, UBIE_GEOSE ;  B9LZA9, UBIE_GEOSF ;  Q74EU2, UBIE_GEOSL ;
DR   C6E4U6, UBIE_GEOSM ;  C5D3E5, UBIE_GEOSW ;  A5GA37, UBIE_GEOUR ;
DR   P59911, UBIE_HAEDU ;  Q2SN12, UBIE_HAHCH ;  Q5QYG2, UBIE_IDILO ;
DR   B5XYI1, UBIE_KLEP3 ;  A6TGL3, UBIE_KLEP7 ;  Q74LY0, UBIE_LACJO ;
DR   P49016, UBIE_LACLA ;  Q88SI6, UBIE_LACPL ;  C1DCV3, UBIE_LARHH ;
DR   Q5X0X6, UBIE_LEGPA ;  A5II90, UBIE_LEGPC ;  Q5ZRH9, UBIE_LEGPH ;
DR   Q5WSQ8, UBIE_LEGPL ;  Q75FL1, UBIE_LEPIC ;  Q8EXJ3, UBIE_LEPIN ;
DR   P67056, UBIE_LISIN ;  C1KWN1, UBIE_LISMC ;  Q71Y84, UBIE_LISMF ;
DR   B8DBZ5, UBIE_LISMH ;  P67055, UBIE_LISMO ;  A0AK43, UBIE_LISW6 ;
DR   B1HTA6, UBIE_LYSSC ;  A6VTA1, UBIE_MARMS ;  Q606J9, UBIE_METCA ;
DR   B8IJ00, UBIE_METNO ;  O66128, UBIE_MICLU ;  B1MHC3, UBIE_MYCA9 ;
DR   P0A639, UBIE_MYCBO ;  A1KG35, UBIE_MYCBP ;  C1AKN8, UBIE_MYCBT ;
DR   A4T183, UBIE_MYCGI ;  Q9CBA8, UBIE_MYCLE ;  B2HRQ2, UBIE_MYCMM ;
DR   Q73SL8, UBIE_MYCPA ;  A0QRH1, UBIE_MYCS2 ;  A3PUJ1, UBIE_MYCSJ ;
DR   A1UAY5, UBIE_MYCSK ;  Q1BE01, UBIE_MYCSS ;  A5TZT8, UBIE_MYCTA ;
DR   P0A638, UBIE_MYCTU ;  A0PLV5, UBIE_MYCUA ;  A1T3S1, UBIE_MYCVP ;
DR   Q5F9R9, UBIE_NEIG1 ;  B4RK11, UBIE_NEIG2 ;  A9M3A0, UBIE_NEIM0 ;
DR   Q9JV83, UBIE_NEIMA ;  Q9K075, UBIE_NEIMB ;  A1KT06, UBIE_NEIMF ;
DR   Q81ZZ8, UBIE_NITEU ;  Q1QS47, UBIE_NITHX ;  Q2Y6R0, UBIE_NITMU ;
DR   Q5YPB0, UBIE_NOCFA ;  A1SE26, UBIE_NOCSJ ;  B2IUM7, UBIE_NOSP7 ;
DR   Q8YLP4, UBIE_NOSS1 ;  Q8CWG0, UBIE_OCEIH ;  A6WYI0, UBIE_OCHA4 ;
DR   A1BAN1, UBIE_PARDP ;  Q6MCB5, UBIE_PARUW ;  Q9CKD6, UBIE_PASMU ;
DR   C6DI77, UBIE_PECCP ;  Q3A209, UBIE_PELCD ;  B4RC42, UBIE_PHEZH ;
DR   Q7MZ81, UBIE_PHOLL ;  B2RJE9, UBIE_PORG3 ;  Q7MVR7, UBIE_PORGI ;
DR   B4EWC9, UBIE_PROMH ;  Q48PJ4, UBIE_PSE14 ;  A6VDI6, UBIE_PSEA7 ;
DR   B7V3F6, UBIE_PSEA8 ;  Q02EV4, UBIE_PSEAB ;  Q9HUC0, UBIE_PSEAE ;
DR   Q1I3T0, UBIE_PSEE4 ;  C3K8U4, UBIE_PSEFS ;  Q3IJV7, UBIE_PSEHT ;
DR   A4XPM7, UBIE_PSEMY ;  Q9Z5E9, UBIE_PSEOL ;  A5WA45, UBIE_PSEP1 ;
DR   Q3KJC5, UBIE_PSEPF ;  B0KM36, UBIE_PSEPG ;  Q88D17, UBIE_PSEPK ;
DR   Q9Z439, UBIE_PSEPU ;  B1J2S8, UBIE_PSEPW ;  Q87UZ2, UBIE_PSESM ;
DR   Q4ZZG3, UBIE_PSEU2 ;  A4VGE5, UBIE_PSEU5 ;  A1SRS4, UBIE_PSYIN ;
DR   Q1LRG9, UBIE_RALME ;  B2UFG8, UBIE_RALPJ ;  Q8Y278, UBIE_RALSO ;
DR   A9WRT1, UBIE_RENSM ;  B3PZ92, UBIE_RHIE6 ;  Q2KDB0, UBIE_RHIEC ;
DR   Q1MME0, UBIE_RHIL3 ;  Q98GV1, UBIE_RHILO ;  B5ZYK8, UBIE_RHILW ;
DR   Q92SK7, UBIE_RHIME ;  C3MCY6, UBIE_RHISN ;  P59912, UBIE_RHOBA ;
DR   Q2J2H9, UBIE_RHOP2 ;  Q6NDM2, UBIE_RHOPA ;  Q13EN8, UBIE_RHOPS ;
DR   B3Q619, UBIE_RHOPT ;  A3PFL1, UBIE_RHOS1 ;  Q3IY65, UBIE_RHOS4 ;
DR   A4WVR7, UBIE_RHOS5 ;  B9KQJ8, UBIE_RHOSK ;  C3PLF4, UBIE_RICAE ;
DR   A8GPI0, UBIE_RICAH ;  A8GXR2, UBIE_RICB8 ;  Q1RJY5, UBIE_RICBR ;
DR   A8EZP4, UBIE_RICCK ;  Q92GT5, UBIE_RICCN ;  Q4UMW4, UBIE_RICFE ;
DR   A8F2G9, UBIE_RICM5 ;  Q9ZCP3, UBIE_RICPR ;  C4K2K3, UBIE_RICPU ;
DR   B0BUT9, UBIE_RICRO ;  A8GT99, UBIE_RICRS ;  Q68W57, UBIE_RICTY ;
DR   A7NF26, UBIE_ROSCS ;  Q16DL1, UBIE_ROSDO ;  A5UVB2, UBIE_ROSS1 ;
DR   Q9JPD1, UBIE_RUBGE ;  Q21H69, UBIE_SACD2 ;  B5EZU8, UBIE_SALA4 ;
DR   A9MIY3, UBIE_SALAR ;  Q57HN8, UBIE_SALCH ;  B5FNW6, UBIE_SALDC ;
DR   B5QW73, UBIE_SALEP ;  B5RFM8, UBIE_SALG2 ;  B4TBR3, UBIE_SALHS ;
DR   B4SZ73, UBIE_SALNS ;  Q5PKP4, UBIE_SALPA ;  A9MY97, UBIE_SALPB ;
DR   C0Q3E1, UBIE_SALPC ;  B5BIX9, UBIE_SALPK ;  B4TNX9, UBIE_SALSV ;
DR   P0A2K6, UBIE_SALTI ;  P0A2K5, UBIE_SALTY ;  A8G8B8, UBIE_SERP5 ;
DR   A1SAJ8, UBIE_SHEAM ;  B8E6B6, UBIE_SHEB2 ;  A3D9F2, UBIE_SHEB5 ;
DR   A6WIE9, UBIE_SHEB8 ;  A9KYL8, UBIE_SHEB9 ;  Q12S23, UBIE_SHEDO ;
DR   Q088H8, UBIE_SHEFN ;  B0TJ16, UBIE_SHEHH ;  A3QIE1, UBIE_SHELP ;
DR   Q8E9R7, UBIE_SHEON ;  A8H966, UBIE_SHEPA ;  A4Y2Q5, UBIE_SHEPC ;
DR   B8CI06, UBIE_SHEPW ;  A0L1M4, UBIE_SHESA ;  A8G0S7, UBIE_SHESH ;
DR   Q0HEA1, UBIE_SHESM ;  Q0HZP7, UBIE_SHESR ;  A1RP78, UBIE_SHESW ;
DR   B1KR07, UBIE_SHEWM ;  B2TVI4, UBIE_SHIB3 ;  Q31UF3, UBIE_SHIBS ;
DR   Q32A11, UBIE_SHIDS ;  Q0SZ25, UBIE_SHIF8 ;  P0A889, UBIE_SHIFL ;
DR   Q3YVD2, UBIE_SHISS ;  Q1GC56, UBIE_SILST ;  A6UFF7, UBIE_SINMW ;
DR   A7X2H6, UBIE_STAA1 ;  A6U1T9, UBIE_STAA2 ;  A5ISZ9, UBIE_STAA9 ;
DR   Q2YY85, UBIE_STAAB ;  Q5HFV2, UBIE_STAAC ;  A6QH20, UBIE_STAAE ;
DR   P67061, UBIE_STAAM ;  P67062, UBIE_STAAN ;  Q6GGU0, UBIE_STAAR ;
DR   Q6G992, UBIE_STAAS ;  A8Z450, UBIE_STAAT ;  P67063, UBIE_STAAW ;
DR   B9DNV5, UBIE_STACT ;  Q5HP74, UBIE_STAEQ ;  Q8CSH9, UBIE_STAES ;
DR   Q4L6H3, UBIE_STAHJ ;  Q49XS5, UBIE_STAS1 ;  Q81ZX2, UBIE_STRAW ;
DR   Q9XAP8, UBIE_STRCO ;  B1W525, UBIE_STRGG ;  B4SJ34, UBIE_STRM5 ;
DR   B2FUU6, UBIE_STRMK ;  Q67LE6, UBIE_SYMTH ;  Q31P90, UBIE_SYNE7 ;
DR   Q5N4X9, UBIE_SYNP6 ;  P72818, UBIE_SYNY3 ;  C5BRL2, UBIE_TERTT ;
DR   Q8DGE4, UBIE_THEEB ;  Q47LE2, UBIE_THEFY ;  Q9WZL2, UBIE_THEMA ;
DR   Q72HI4, UBIE_THET2 ;  Q31IM5, UBIE_THICR ;  Q3SM81, UBIE_THIDA ;
DR   P67065, UBIE_TROW8 ;  P67064, UBIE_TROWT ;  A5F4E5, UBIE_VIBC3 ;
DR   Q9KVQ6, UBIE_VIBCH ;  C3LPS5, UBIE_VIBCM ;  A7MTX1, UBIE_VIBHB ;
DR   Q87TH4, UBIE_VIBPA ;  Q8DDP9, UBIE_VIBVU ;  Q7MQ33, UBIE_VIBVY ;
DR   Q8D382, UBIE_WIGBR ;  Q73HZ4, UBIE_WOLPM ;  C0R2Q3, UBIE_WOLWR ;
DR   Q8PPP2, UBIE_XANAC ;  Q8P558, UBIE_XANCP ;  Q2NYW4, UBIE_XANOM ;
DR   B2IA21, UBIE_XYLF2 ;  Q9PD92, UBIE_XYLFA ;  B0U6V1, UBIE_XYLFM ;
DR   Q87DI1, UBIE_XYLFT ;  A1JIF2, UBIE_YERE8 ;  A7FDE0, UBIE_YERP3 ;
DR   Q1CBG0, UBIE_YERPA ;  B2K0Y4, UBIE_YERPB ;  Q8D1I3, UBIE_YERPE ;
DR   A9R431, UBIE_YERPG ;  Q1CNB4, UBIE_YERPN ;  A4TR39, UBIE_YERPP ;
DR   Q66FT0, UBIE_YERPS ;  B1JP75, UBIE_YERPY ;  Q9X3X2, UBIE_ZYMMO ;
//
ID   2.1.1.164
DE   Demethylrebeccamycin-D-glucose O-methyltransferase.
CA   4'-demethylrebeccamycin + S-adenosyl-L-methionine = rebeccamycin +
CA   S-adenosyl-L-homocysteine.
CC   -!- Catalyzes the last step in the biosynthesis of rebeccamycin,
CC       an indolocarbazole alkaloid produced by the actinobacterium
CC       Lechevalieria aerocolonigenes.
CC   -!- The enzyme is able to use a wide variety substrates, tolerating
CC       variation on the imide heterocycle, deoxygenation of the sugar
CC       moiety, and even indolocarbazole glycoside anomers.
//
ID   2.1.1.165
DE   Methyl halide transferase.
AN   Methyl chloride transferase.
CA   S-adenosyl-L-methionine + iodide = S-adenosyl-L-homocysteine + methyl
CA   iodide.
CC   -!- This enzyme contributes to the methyl halide emissions from
CC       Arabidopsis.
//
ID   2.1.1.166
DE   23S rRNA (uridine(2552)-2'-O-)-methyltransferase.
AN   FTSJ.
AN   Um(2552) 23S ribosomal RNA methyltransferase.
AN   Um2552 methyltransferase.
CA   S-adenosyl-L-methionine + uridine(2552) in 23S rRNA = S-adenosyl-L-
CA   homocysteine + 2'-O-methyluridine(2552) in 23S rRNA.
CC   -!- The enzyme catalyzes the 2'-O-methylation of the universally
CC       conserved U2552 in the A loop of 23S rRNA.
DR   A1TQF0, RLME_ACIAC ;  Q6F8N1, RLME_ACIAD ;  B7GY18, RLME_ACIB3 ;
DR   B7I636, RLME_ACIB5 ;  B2HXD3, RLME_ACIBC ;  B0VSM4, RLME_ACIBS ;
DR   A3M851, RLME_ACIBT ;  B0VEE9, RLME_ACIBY ;  A5G029, RLME_ACICJ ;
DR   B7J8G6, RLME_ACIF2 ;  B5ENR5, RLME_ACIF5 ;  A1W8H0, RLME_ACISJ ;
DR   A3MZW0, RLME_ACTP2 ;  B3H123, RLME_ACTP7 ;  B0BUF3, RLME_ACTPJ ;
DR   A6VPC2, RLME_ACTSZ ;  A0KNF1, RLME_AERHH ;  A4SJQ7, RLME_AERS4 ;
DR   B9J9U0, RLME_AGRRK ;  Q8UHR0, RLME_AGRT5 ;  B9JSD2, RLME_AGRVS ;
DR   Q0VSS9, RLME_ALCBS ;  Q0A769, RLME_ALHEH ;  B6END5, RLME_ALISL ;
DR   Q2IPT3, RLME_ANADE ;  A7H9A5, RLME_ANADF ;  B9KIP4, RLME_ANAMF ;
DR   Q5PAN0, RLME_ANAMM ;  Q2GKK2, RLME_ANAPZ ;  O28228, RLME_ARCFU ;
DR   Q5P1G0, RLME_AROAE ;  A8II77, RLME_AZOC5 ;  A1K598, RLME_AZOSB ;
DR   C1DFL6, RLME_AZOVD ;  A1URN3, RLME_BARBK ;  Q6G4Z3, RLME_BARHE ;
DR   Q6G0S9, RLME_BARQU ;  A9IMA1, RLME_BART1 ;  Q1LSK2, RLME_BAUCH ;
DR   Q6MN40, RLME_BDEBA ;  Q7VQM8, RLME_BLOFL ;  Q493U3, RLME_BLOPB ;
DR   Q2KVR5, RLME_BORA1 ;  Q0SNJ8, RLME_BORAP ;  Q7WMD3, RLME_BORBR ;
DR   O51293, RLME_BORBU ;  B7J1P0, RLME_BORBZ ;  B5RLD9, RLME_BORDL ;
DR   Q661V2, RLME_BORGA ;  Q7W8R6, RLME_BORPA ;  A9HYV0, RLME_BORPD ;
DR   Q7VZ56, RLME_BORPE ;  B5RRD2, RLME_BORRA ;  C0QX75, RLME_BRAHW ;
DR   Q89N72, RLME_BRAJA ;  A5EHP2, RLME_BRASB ;  A4YSS3, RLME_BRASO ;
DR   B2SAY0, RLME_BRUA1 ;  Q2YKU4, RLME_BRUA2 ;  Q578H4, RLME_BRUAB ;
DR   A9MBW8, RLME_BRUC2 ;  C0RLJ5, RLME_BRUMB ;  Q8YCD5, RLME_BRUME ;
DR   A5VUZ8, RLME_BRUO2 ;  A9WYY2, RLME_BRUSI ;  Q8FVY1, RLME_BRUSU ;
DR   P57463, RLME_BUCAI ;  Q8K9G7, RLME_BUCAP ;  Q89AF1, RLME_BUCBP ;
DR   Q057J5, RLME_BUCCC ;  B1YMW2, RLME_BURA4 ;  Q1BXD0, RLME_BURCA ;
DR   B1JZE9, RLME_BURCC ;  A0K6C1, RLME_BURCH ;  B4E5F3, RLME_BURCJ ;
DR   Q0BGJ2, RLME_BURCM ;  A9ACL8, RLME_BURM1 ;  A3MIQ3, RLME_BURM7 ;
DR   A2S3Q7, RLME_BURM9 ;  Q62L80, RLME_BURMA ;  A1V319, RLME_BURMS ;
DR   A3NTW3, RLME_BURP0 ;  Q3JTT5, RLME_BURP1 ;  A3N853, RLME_BURP6 ;
DR   B2JFN9, RLME_BURP8 ;  B2SZR9, RLME_BURPP ;  Q63V86, RLME_BURPS ;
DR   Q39HN2, RLME_BURS3 ;  Q2SUW0, RLME_BURTA ;  A4JDA6, RLME_BURVG ;
DR   Q13W47, RLME_BURXL ;  Q9A7V4, RLME_CAUCR ;  B0T8J6, RLME_CAUSK ;
DR   B3PLQ4, RLME_CELJU ;  A0RV28, RLME_CENSY ;  Q1QSY2, RLME_CHRSD ;
DR   Q7NRI3, RLME_CHRVO ;  A8AQ68, RLME_CITK8 ;  Q47YJ3, RLME_COLP3 ;
DR   B6J802, RLME_COXB1 ;  B6IZD5, RLME_COXB2 ;  A9KGE6, RLME_COXBN ;
DR   A9N8M5, RLME_COXBR ;  Q83BY4, RLME_COXBU ;  Q0K8Y4, RLME_CUPNH ;
DR   Q46Z98, RLME_CUPPJ ;  B3R1S2, RLME_CUPTR ;  Q47HI2, RLME_DECAR ;
DR   A9BML0, RLME_DELAS ;  B8FL12, RLME_DESAA ;  C6C068, RLME_DESAD ;
DR   C0QGP2, RLME_DESAH ;  Q30YX3, RLME_DESDG ;  A8ZT18, RLME_DESOH ;
DR   Q6AJ42, RLME_DESPS ;  Q729T9, RLME_DESVH ;  B8DNJ4, RLME_DESVM ;
DR   A1VC40, RLME_DESVV ;  A5EXB6, RLME_DICNV ;  A7ZS75, RLME_ECO24 ;
DR   B7UJ72, RLME_ECO27 ;  B7MBU8, RLME_ECO45 ;  B7LHP2, RLME_ECO55 ;
DR   P0C0R8, RLME_ECO57 ;  B5YS68, RLME_ECO5E ;  B7NKP6, RLME_ECO7I ;
DR   B7N363, RLME_ECO81 ;  B7M085, RLME_ECO8A ;  C4ZSR8, RLME_ECOBW ;
DR   B1XGY9, RLME_ECODH ;  A8A4Z3, RLME_ECOHS ;  A1AG82, RLME_ECOK1 ;
DR   Q0TCT1, RLME_ECOL5 ;  P0C0R9, RLME_ECOL6 ;  B1IQU4, RLME_ECOLC ;
DR   P0C0R7, RLME_ECOLI ;  B7NDG3, RLME_ECOLU ;  B6I1Q2, RLME_ECOSE ;
DR   B1LFS9, RLME_ECOSM ;  Q1R6F9, RLME_ECOUT ;  C5BFB0, RLME_EDWI9 ;
DR   Q3YRW8, RLME_EHRCJ ;  Q2GGT6, RLME_EHRCR ;  Q5FH15, RLME_EHRRG ;
DR   Q5FEH6, RLME_EHRRW ;  A4WEZ0, RLME_ENT38 ;  A7MIM8, RLME_ENTS8 ;
DR   Q6D9B9, RLME_ERWCT ;  B2VGT0, RLME_ERWT9 ;  Q2N843, RLME_ERYLH ;
DR   B7LR46, RLME_ESCF3 ;  B0TZQ8, RLME_FRAP2 ;  Q14HT5, RLME_FRAT1 ;
DR   A7NAC9, RLME_FRATF ;  Q2A4Z7, RLME_FRATH ;  B2SF85, RLME_FRATM ;
DR   A0Q526, RLME_FRATN ;  Q0BNB8, RLME_FRATO ;  Q5NGD3, RLME_FRATT ;
DR   A4IYP4, RLME_FRATW ;  Q5FNQ1, RLME_GLUOX ;  Q0BT08, RLME_GRABC ;
DR   Q7VLF2, RLME_HAEDU ;  Q4QKJ2, RLME_HAEI8 ;  P45162, RLME_HAEIN ;
DR   B8F4C0, RLME_HAEPS ;  Q0I2R1, RLME_HAES1 ;  Q2SMM1, RLME_HAHCH ;
DR   A1WXX3, RLME_HALHL ;  B9LSX2, RLME_HALLT ;  Q5UYP9, RLME_HALMA ;
DR   B0R7G3, RLME_HALS3 ;  Q9HN40, RLME_HALSA ;  Q18E61, RLME_HALWD ;
DR   C4K7K8, RLME_HAMD5 ;  A4G4B0, RLME_HERAR ;  Q0C187, RLME_HYPNA ;
DR   Q5QXK8, RLME_IDILO ;  A6T081, RLME_JANMA ;  Q28QW4, RLME_JANSC ;
DR   B5XSW2, RLME_KLEP3 ;  A6TEJ8, RLME_KLEP7 ;  Q1MRQ0, RLME_LAWIP ;
DR   Q5X1A0, RLME_LEGPA ;  A5IHX0, RLME_LEGPC ;  Q5ZRT1, RLME_LEGPH ;
DR   Q5WT13, RLME_LEGPL ;  B1XXG3, RLME_LEPCP ;  Q2W0P2, RLME_MAGSA ;
DR   A0LC14, RLME_MAGSM ;  Q65TZ0, RLME_MANSM ;  A1TXM4, RLME_MARAV ;
DR   Q0AQH3, RLME_MARMM ;  Q11L51, RLME_MESSB ;  A6UUK5, RLME_META3 ;
DR   Q8TR92, RLME_METAC ;  A7I848, RLME_METB6 ;  Q466Q1, RLME_METBF ;
DR   Q12WR3, RLME_METBU ;  Q607B2, RLME_METCA ;  Q1H387, RLME_METFK ;
DR   Q2FNX6, RLME_METHJ ;  Q58771, RLME_METJA ;  A2SSW7, RLME_METLZ ;
DR   A4FYM2, RLME_METM5 ;  A9A6B9, RLME_METM6 ;  A6VJR0, RLME_METM7 ;
DR   Q8PUP4, RLME_METMA ;  A3CVJ3, RLME_METMJ ;  Q6LZL8, RLME_METMP ;
DR   B8GG79, RLME_METPE ;  A2SF90, RLME_METPP ;  A5UKI5, RLME_METS3 ;
DR   Q2NHD6, RLME_METST ;  O27801, RLME_METTH ;  A0B8A1, RLME_METTP ;
DR   A6USA0, RLME_METVS ;  Q1D841, RLME_MYXXD ;  Q3IT24, RLME_NATPD ;
DR   Q5F9L0, RLME_NEIG1 ;  B4RK82, RLME_NEIG2 ;  A9M3N1, RLME_NEIM0 ;
DR   Q9JQX5, RLME_NEIMA ;  Q7DDL2, RLME_NEIMB ;  A1KT57, RLME_NEIMF ;
DR   Q2GDL7, RLME_NEOSM ;  Q0AHC6, RLME_NITEC ;  Q820A2, RLME_NITEU ;
DR   Q1QKB6, RLME_NITHX ;  A9A3M9, RLME_NITMS ;  Q2YBT1, RLME_NITMU ;
DR   Q3J823, RLME_NITOC ;  Q3SQN7, RLME_NITWN ;  Q2GB53, RLME_NOVAD ;
DR   A6X5L4, RLME_OCHA4 ;  B6JHM9, RLME_OLICO ;  A1B962, RLME_PARDP ;
DR   A7HSA5, RLME_PARL1 ;  Q9CNJ3, RLME_PASMU ;  C6DKI3, RLME_PECCP ;
DR   Q4FMX1, RLME_PELUB ;  Q7MYY0, RLME_PHOLL ;  Q6LUJ9, RLME_PHOPR ;
DR   Q6L1E2, RLME_PICTO ;  A1VQI6, RLME_POLNA ;  Q129M4, RLME_POLSJ ;
DR   A4SXL6, RLME_POLSQ ;  B4F2B2, RLME_PROMH ;  Q48E69, RLME_PSE14 ;
DR   Q15VJ6, RLME_PSEA6 ;  A6VCK9, RLME_PSEA7 ;  B7V1G4, RLME_PSEA8 ;
DR   Q02FS0, RLME_PSEAB ;  P95454, RLME_PSEAE ;  Q1IF51, RLME_PSEE4 ;
DR   Q4KIG3, RLME_PSEF5 ;  C3K267, RLME_PSEFS ;  Q3IE64, RLME_PSEHT ;
DR   A4XYE8, RLME_PSEMY ;  A5W995, RLME_PSEP1 ;  Q3KI92, RLME_PSEPF ;
DR   B0KHY6, RLME_PSEPG ;  Q88DV0, RLME_PSEPK ;  B1J262, RLME_PSEPW ;
DR   Q87WP7, RLME_PSESM ;  Q4ZNQ4, RLME_PSEU2 ;  A4VNP3, RLME_PSEU5 ;
DR   Q4FQX1, RLME_PSYA2 ;  Q1Q955, RLME_PSYCK ;  A1ST38, RLME_PSYIN ;
DR   A5WCU8, RLME_PSYWF ;  Q1LLA8, RLME_RALME ;  B2UGQ0, RLME_RALPJ ;
DR   Q8XZ79, RLME_RALSO ;  B3PQL4, RLME_RHIE6 ;  Q2KC36, RLME_RHIEC ;
DR   Q1ML15, RLME_RHIL3 ;  Q983F8, RLME_RHILO ;  B5ZR94, RLME_RHILW ;
DR   Q92RT9, RLME_RHIME ;  C3MGQ4, RLME_RHISN ;  Q21WW8, RLME_RHOFD ;
DR   Q2IV68, RLME_RHOP2 ;  Q07LH9, RLME_RHOP5 ;  Q6N7Q9, RLME_RHOPA ;
DR   Q212R3, RLME_RHOPB ;  Q138J5, RLME_RHOPS ;  B3QFD2, RLME_RHOPT ;
DR   Q2RXU5, RLME_RHORT ;  A3PJK8, RLME_RHOS1 ;  Q3J2Q5, RLME_RHOS4 ;
DR   C3PMK3, RLME_RICAE ;  A8GMD3, RLME_RICAH ;  A8GV60, RLME_RICB8 ;
DR   Q1RHG3, RLME_RICBR ;  A8EXN1, RLME_RICCK ;  Q92J64, RLME_RICCN ;
DR   Q4UKG2, RLME_RICFE ;  Q9ZE00, RLME_RICPR ;  C4K0Q4, RLME_RICPU ;
DR   B0BWD8, RLME_RICRO ;  A8GQZ0, RLME_RICRS ;  Q68XK5, RLME_RICTY ;
DR   Q164M8, RLME_ROSDO ;  A1AW32, RLME_RUTMC ;  Q21H48, RLME_SACD2 ;
DR   B5F6U7, RLME_SALA4 ;  A9MP28, RLME_SALAR ;  Q57JH1, RLME_SALCH ;
DR   B5FI23, RLME_SALDC ;  B5R0H0, RLME_SALEP ;  B5REP5, RLME_SALG2 ;
DR   B4TJ16, RLME_SALHS ;  B4T708, RLME_SALNS ;  Q5PLC1, RLME_SALPA ;
DR   A9N744, RLME_SALPB ;  C0PZ62, RLME_SALPC ;  B5BGK3, RLME_SALPK ;
DR   B4TWE7, RLME_SALSV ;  Q8Z3H3, RLME_SALTI ;  Q8ZLS7, RLME_SALTY ;
DR   A8G900, RLME_SERP5 ;  A1S454, RLME_SHEAM ;  B8E6M4, RLME_SHEB2 ;
DR   A3D7L4, RLME_SHEB5 ;  A6WRH7, RLME_SHEB8 ;  A9KZX9, RLME_SHEB9 ;
DR   Q12QI9, RLME_SHEDO ;  Q086I0, RLME_SHEFN ;  B0TQB0, RLME_SHEHH ;
DR   A3QGV3, RLME_SHELP ;  Q8EHM3, RLME_SHEON ;  A8H748, RLME_SHEPA ;
DR   A4Y9C8, RLME_SHEPC ;  B8CKG5, RLME_SHEPW ;  A0KTY8, RLME_SHESA ;
DR   A8FYS8, RLME_SHESH ;  Q0HLG9, RLME_SHESM ;  Q0HXS3, RLME_SHESR ;
DR   A1RGW7, RLME_SHESW ;  B1KRR8, RLME_SHEWM ;  B2U1Z8, RLME_SHIB3 ;
DR   Q31W56, RLME_SHIBS ;  Q32BF4, RLME_SHIDS ;  Q0T0A5, RLME_SHIF8 ;
DR   P0C0S0, RLME_SHIFL ;  Q3YX62, RLME_SHISS ;  Q5LSB0, RLME_SILPO ;
DR   Q1GHF1, RLME_SILST ;  A6U6F0, RLME_SINMW ;  Q2NW30, RLME_SODGM ;
DR   A9FQE4, RLME_SORC5 ;  Q1GPG3, RLME_SPHAL ;  A5VFI9, RLME_SPHWW ;
DR   B4SRA0, RLME_STRM5 ;  B2FKA1, RLME_STRMK ;  A0LGZ0, RLME_SYNFM ;
DR   Q9HIH4, RLME_THEAC ;  Q97C13, RLME_THEVO ;  Q31HG6, RLME_THICR ;
DR   Q3SJR5, RLME_THIDA ;  B8GNX9, RLME_THISH ;  C4L8Y1, RLME_TOLAT ;
DR   Q73L97, RLME_TREDE ;  O83687, RLME_TREPA ;  Q8KTR0, RLME_TREPR ;
DR   B2S3S1, RLME_TREPS ;  Q0W1F9, RLME_UNCMA ;  C5CKU4, RLME_VARPS ;
DR   A1WEE7, RLME_VEREI ;  A5CX75, RLME_VESOH ;  A5F937, RLME_VIBC3 ;
DR   Q9KU87, RLME_VIBCH ;  C3LSP1, RLME_VIBCM ;  Q5E7M3, RLME_VIBF1 ;
DR   B5FA72, RLME_VIBFM ;  A7MZH4, RLME_VIBHB ;  Q87LZ4, RLME_VIBPA ;
DR   B7VJI4, RLME_VIBSL ;  Q8DBW7, RLME_VIBVU ;  Q7MI01, RLME_VIBVY ;
DR   Q8D2X0, RLME_WIGBR ;  Q73IS9, RLME_WOLPM ;  Q5GS59, RLME_WOLTR ;
DR   Q8PLQ8, RLME_XANAC ;  Q3BUR8, RLME_XANC5 ;  Q4UTQ4, RLME_XANC8 ;
DR   B0RTZ3, RLME_XANCB ;  Q8P9Y1, RLME_XANCP ;  Q2P1M0, RLME_XANOM ;
DR   B2SUB8, RLME_XANOP ;  Q5GYL7, RLME_XANOR ;  A7IDJ5, RLME_XANP2 ;
DR   B2I696, RLME_XYLF2 ;  Q9PH52, RLME_XYLFA ;  B0U1F2, RLME_XYLFM ;
DR   Q87F66, RLME_XYLFT ;  A1JIW2, RLME_YERE8 ;  A7FMS9, RLME_YERP3 ;
DR   Q1CC00, RLME_YERPA ;  B2K2P8, RLME_YERPB ;  Q8ZBB5, RLME_YERPE ;
DR   Q1CEK6, RLME_YERPN ;  A4TRJ0, RLME_YERPP ;  Q66F67, RLME_YERPS ;
DR   B1JMH7, RLME_YERPY ;  Q5NQH8, RLME_ZYMMO ;
//
ID   2.1.1.167
DE   27S pre-rRNA (guanosine(2922)-2'-O-)-methyltransferase.
CA   S-adenosyl-L-methionine + guanosine(2922) in 27S pre-rRNA = S-adenosyl-L-
CA   homocysteine + 2'-O-methylguanosine(2922) in 27S pre-rRNA.
CC   -!- Spb1p is a site-specific 2'-O-ribose RNA methyltransferase that
CC       catalyzes the formation of 2'-O-methylguanosine(2922), a universally
CC       conserved position of the catalytic center of the ribosome that is
CC       essential for translation.
CC   -!- 2'-O-Methylguanosine(2922) is formed at a later stage of the
CC       processing, during the maturation of of the 27S pre-rRNA.
CC   -!- In absence of snR52, Spb1p can also catalyze the formation of
CC       uridine(2921).
//
ID   2.1.1.168
DE   21S rRNA (uridine(2791)-2'-O-)-methyltransferase.
AN   Mitochondrial rRNA MTase 2.
CA   S-adenosyl-L-methionine + uridine(2791)-2'-O in 21S rRNA = S-adenosyl-L-
CA   homocysteine + 2'-O-methyluridine(2791)-2'-O in 21S rRNA.
CC   -!- The enzyme catalyzes the methylation of uridine(2791) of
CC       mitochondrial 21S rRNA.
DR   P53123, MRM2_YEAST ;
//
ID   2.1.1.169
DE   Tricetin 3',4',5'-O-trimethyltransferase.
CA   3 S-adenosyl-L-methionine + tricetin = 3 S-adenosyl-L-homocysteine +
CA   3',4',5'-O-trimethyltricetin.
CC   -!- The enzyme from Triticum aestivum catalyzes the sequential
CC       O-methylation of tricetin via 3'-O-methyltricetin, 3',5'-O-
CC       methyltricetin to 3',4',5'-O-trimethyltricetin (2).
DR   Q38J50, FOMT2_WHEAT;
//
ID   2.1.1.170
DE   16S rRNA (guanine(527)-N(7))-methyltransferase.
CA   S-adenosyl-L-methionine + guanosine(527) in 16S rRNA = S-adenosyl-L-
CA   homocysteine + N(7)-methylguanosine(527) in 16S rRNA.
CC   -!- The enzyme specifically methylates guanine(527) at N(7) in 16S rRNA.
DR   Q6MQY9, RSMG1_BDEBA;  A0LLH7, RSMG1_SYNFM;  Q6MMJ3, RSMG2_BDEBA;
DR   A0LHE3, RSMG2_SYNFM;  Q6MGL7, RSMG3_BDEBA;  A1TI79, RSMG_ACIAC ;
DR   Q6F9W7, RSMG_ACIAD ;  B7H3N1, RSMG_ACIB3 ;  B7I508, RSMG_ACIB5 ;
DR   B2HZC3, RSMG_ACIBC ;  B0VMY0, RSMG_ACIBS ;  A3M4Y3, RSMG_ACIBT ;
DR   B0VCZ6, RSMG_ACIBY ;  A5G167, RSMG_ACICJ ;  B9M9W4, RSMG_ACIET ;
DR   A1W208, RSMG_ACISJ ;  A3N2V2, RSMG_ACTP2 ;  B3H2Q1, RSMG_ACTP7 ;
DR   B0BRY0, RSMG_ACTPJ ;  A6VL65, RSMG_ACTSZ ;  A0KQY8, RSMG_AERHH ;
DR   A4STQ3, RSMG_AERS4 ;  B9JEW2, RSMG_AGRRK ;  Q8UBM1, RSMG_AGRT5 ;
DR   B9JV51, RSMG_AGRVS ;  Q0VKW4, RSMG_ALCBS ;  Q0A4L8, RSMG_ALHEH ;
DR   B4RS91, RSMG_ALTMD ;  B8JDK2, RSMG_ANAD2 ;  Q2IHR2, RSMG_ANADE ;
DR   A7HIY6, RSMG_ANADF ;  B4UKF8, RSMG_ANASK ;  A8EU69, RSMG_ARCB4 ;
DR   Q5P4J7, RSMG_AROAE ;  A8I267, RSMG_AZOC5 ;  A1K1Q5, RSMG_AZOSB ;
DR   A1UQU8, RSMG_BARBK ;  Q6G1L0, RSMG_BARHE ;  Q6FYC0, RSMG_BARQU ;
DR   A9IZX8, RSMG_BART1 ;  Q2L2S3, RSMG_BORA1 ;  Q7WRF0, RSMG_BORBR ;
DR   Q7W2I0, RSMG_BORPA ;  A9IJ46, RSMG_BORPD ;  Q7W0S9, RSMG_BORPE ;
DR   Q89WP6, RSMG_BRAJA ;  A5E8G9, RSMG_BRASB ;  A4YJT3, RSMG_BRASO ;
DR   B2S959, RSMG_BRUA1 ;  Q2YR13, RSMG_BRUA2 ;  Q57AJ8, RSMG_BRUAB ;
DR   A9M9E3, RSMG_BRUC2 ;  C0RFU8, RSMG_BRUMB ;  Q8YJS4, RSMG_BRUME ;
DR   A5VT18, RSMG_BRUO2 ;  B0CJG0, RSMG_BRUSI ;  Q8FY29, RSMG_BRUSU ;
DR   B1YQK3, RSMG_BURA4 ;  Q1BR98, RSMG_BURCA ;  A0K2X1, RSMG_BURCH ;
DR   B4E582, RSMG_BURCJ ;  Q0BJM7, RSMG_BURCM ;  A9AJF2, RSMG_BURM1 ;
DR   A3MQI8, RSMG_BURM7 ;  A2S6K9, RSMG_BURM9 ;  Q62FS7, RSMG_BURMA ;
DR   A1V8U2, RSMG_BURMS ;  A3P103, RSMG_BURP0 ;  Q3JXU8, RSMG_BURP1 ;
DR   A3NF53, RSMG_BURP6 ;  Q63PG9, RSMG_BURPS ;  Q39KY8, RSMG_BURS3 ;
DR   Q2STD8, RSMG_BURTA ;  A4JA23, RSMG_BURVG ;  Q13SP1, RSMG_BURXL ;
DR   A7ZCL5, RSMG_CAMC1 ;  A7GZM1, RSMG_CAMC5 ;  A0RR76, RSMG_CAMFF ;
DR   A7I3X1, RSMG_CAMHC ;  A8FM46, RSMG_CAMJ8 ;  A7H342, RSMG_CAMJD ;
DR   Q9PNU3, RSMG_CAMJE ;  A1VZY5, RSMG_CAMJJ ;  Q5HUG5, RSMG_CAMJR ;
DR   B8GW32, RSMG_CAUCN ;  P0CAW6, RSMG_CAUCR ;  B0T6E2, RSMG_CAUSK ;
DR   B3PIT7, RSMG_CELJU ;  Q1QSC0, RSMG_CHRSD ;  Q7P0A5, RSMG_CHRVO ;
DR   A8ACP6, RSMG_CITK8 ;  Q47U39, RSMG_COLP3 ;  B6J8V2, RSMG_COXB1 ;
DR   B6J2B9, RSMG_COXB2 ;  A9KBS7, RSMG_COXBN ;  A9NBA9, RSMG_COXBR ;
DR   P94614, RSMG_COXBU ;  Q0K5L7, RSMG_CUPNH ;  Q46VX0, RSMG_CUPPJ ;
DR   Q478A1, RSMG_DECAR ;  Q30Z06, RSMG_DESDG ;  Q6ANR2, RSMG_DESPS ;
DR   Q72CN3, RSMG_DESVH ;  A1VEG3, RSMG_DESVV ;  A5EXK3, RSMG_DICNV ;
DR   A8LPC4, RSMG_DINSH ;  B7UMK5, RSMG_ECO27 ;  B7MGG0, RSMG_ECO45 ;
DR   B7L890, RSMG_ECO55 ;  P0A6U7, RSMG_ECO57 ;  B5YXE4, RSMG_ECO5E ;
DR   B7NR42, RSMG_ECO7I ;  B7N2H9, RSMG_ECO81 ;  B7M596, RSMG_ECO8A ;
DR   C4ZZ18, RSMG_ECOBW ;  B1X9W8, RSMG_ECODH ;  A8A6K3, RSMG_ECOHS ;
DR   A1AHS0, RSMG_ECOK1 ;  Q0TAW9, RSMG_ECOL5 ;  P0A6U6, RSMG_ECOL6 ;
DR   B1IWZ8, RSMG_ECOLC ;  P0A6U5, RSMG_ECOLI ;  B7NF56, RSMG_ECOLU ;
DR   B6I3X7, RSMG_ECOSE ;  B1LL67, RSMG_ECOSM ;  Q1R4J2, RSMG_ECOUT ;
DR   C5BF32, RSMG_EDWI9 ;  A4WGE7, RSMG_ENT38 ;  A7MMW2, RSMG_ENTS8 ;
DR   Q6CYI7, RSMG_ERWCT ;  B2VCB2, RSMG_ERWT9 ;  Q2N6I7, RSMG_ERYLH ;
DR   B7LK85, RSMG_ESCF3 ;  B0TW44, RSMG_FRAP2 ;  Q14FV3, RSMG_FRAT1 ;
DR   A7N992, RSMG_FRATF ;  Q2A5Y4, RSMG_FRATH ;  A0Q444, RSMG_FRATN ;
DR   Q0BP72, RSMG_FRATO ;  Q5NEF0, RSMG_FRATT ;  A4J072, RSMG_FRATW ;
DR   Q39PR1, RSMG_GEOMG ;  Q746Q5, RSMG_GEOSL ;  C6DYR8, RSMG_GEOSM ;
DR   A5G9V1, RSMG_GEOUR ;  A9HE10, RSMG_GLUDA ;  Q5FS13, RSMG_GLUOX ;
DR   Q0BW94, RSMG_GRABC ;  Q7VPP8, RSMG_HAEDU ;  Q4QN56, RSMG_HAEI8 ;
DR   A5UA03, RSMG_HAEIE ;  A5UGZ7, RSMG_HAEIG ;  P44728, RSMG_HAEIN ;
DR   B8F6X2, RSMG_HAEPS ;  Q0I5W5, RSMG_HAES1 ;  B0UWH2, RSMG_HAES2 ;
DR   Q2S6N0, RSMG_HAHCH ;  A1WSY4, RSMG_HALHL ;  Q17WP3, RSMG_HELAH ;
DR   Q8GHA0, RSMG_HELBI ;  Q7VG38, RSMG_HELHP ;  Q1CUC1, RSMG_HELPH ;
DR   Q9ZM61, RSMG_HELPJ ;  O25703, RSMG_HELPY ;  A4GAI1, RSMG_HERAR ;
DR   Q0BWB0, RSMG_HYPNA ;  Q5QZI9, RSMG_IDILO ;  A6T481, RSMG_JANMA ;
DR   Q28VZ4, RSMG_JANSC ;  B5XZL6, RSMG_KLEP3 ;  A6TG44, RSMG_KLEP7 ;
DR   C1D5H2, RSMG_LARHH ;  Q1MR90, RSMG_LAWIP ;  Q5X0Z7, RSMG_LEGPA ;
DR   A5II63, RSMG_LEGPC ;  Q5ZRJ1, RSMG_LEGPH ;  Q5WSS3, RSMG_LEGPL ;
DR   B1XYL2, RSMG_LEPCP ;  Q2WBG8, RSMG_MAGSA ;  A0LE46, RSMG_MAGSM ;
DR   Q65Q00, RSMG_MANSM ;  A1U7I4, RSMG_MARAV ;  Q0AKF0, RSMG_MARMM ;
DR   A6W3T8, RSMG_MARMS ;  Q11CN4, RSMG_MESSB ;  B7KV55, RSMG_METC4 ;
DR   Q60CS4, RSMG_METCA ;  A9W327, RSMG_METEP ;  Q1GXM0, RSMG_METFK ;
DR   B8IHZ7, RSMG_METNO ;  B1ZGG1, RSMG_METPB ;  A2SMF0, RSMG_METPP ;
DR   B1M187, RSMG_METRJ ;  B0UJI7, RSMG_METS4 ;  Q1CVH7, RSMG_MYXXD ;
DR   Q5F5X7, RSMG_NEIG1 ;  B4RR25, RSMG_NEIG2 ;  A9M3R8, RSMG_NEIM0 ;
DR   Q9JX38, RSMG_NEIMA ;  Q9K1G3, RSMG_NEIMB ;  A1KRM2, RSMG_NEIMF ;
DR   Q0ADD7, RSMG_NITEC ;  Q82S79, RSMG_NITEU ;  Q1QRZ2, RSMG_NITHX ;
DR   Q2Y5B5, RSMG_NITMU ;  Q3J6M1, RSMG_NITOC ;  A6Q1W3, RSMG_NITSB ;
DR   Q3SWH7, RSMG_NITWN ;  Q2GC39, RSMG_NOVAD ;  A6WX78, RSMG_OCHA4 ;
DR   A5CDU7, RSMG_ORITB ;  B3CQX7, RSMG_ORITI ;  A1AXX8, RSMG_PARDP ;
DR   A7HSL2, RSMG_PARL1 ;  P57946, RSMG_PASMU ;  C6DJG4, RSMG_PECCP ;
DR   Q39ZT2, RSMG_PELCD ;  A1AV41, RSMG_PELPD ;  Q4FNR5, RSMG_PELUB ;
DR   Q7NA87, RSMG_PHOLL ;  Q6LLF8, RSMG_PHOPR ;  A1VIB2, RSMG_POLNA ;
DR   Q12HF1, RSMG_POLSJ ;  A4SUS4, RSMG_POLSQ ;  Q48BF5, RSMG_PSE14 ;
DR   Q15MT4, RSMG_PSEA6 ;  A6VF42, RSMG_PSEA7 ;  B7V7A1, RSMG_PSEA8 ;
DR   Q02DE4, RSMG_PSEAB ;  Q9HT10, RSMG_PSEAE ;  Q1I2H7, RSMG_PSEE4 ;
DR   Q4K3A0, RSMG_PSEF5 ;  Q3IK40, RSMG_PSEHT ;  A4Y197, RSMG_PSEMY ;
DR   A5WBB3, RSMG_PSEP1 ;  Q3K431, RSMG_PSEPF ;  B0KRB8, RSMG_PSEPG ;
DR   P0A124, RSMG_PSEPK ;  P0A125, RSMG_PSEPU ;  B1JFV1, RSMG_PSEPW ;
DR   Q87TS4, RSMG_PSESM ;  Q4ZL14, RSMG_PSEU2 ;  A4VS72, RSMG_PSEU5 ;
DR   Q4FS37, RSMG_PSYA2 ;  Q1QBW5, RSMG_PSYCK ;  A1T0Z9, RSMG_PSYIN ;
DR   A5WFA2, RSMG_PSYWF ;  Q1LHJ9, RSMG_RALME ;  Q8XU66, RSMG_RALSO ;
DR   B3PS51, RSMG_RHIE6 ;  Q2K2S2, RSMG_RHIEC ;  Q1MA20, RSMG_RHIL3 ;
DR   Q98DZ2, RSMG_RHILO ;  B5ZV45, RSMG_RHILW ;  Q92KW3, RSMG_RHIME ;
DR   C3MB65, RSMG_RHISN ;  B6IV59, RSMG_RHOCS ;  Q21QL4, RSMG_RHOFD ;
DR   Q2J359, RSMG_RHOP2 ;  Q07UP0, RSMG_RHOP5 ;  Q6ND16, RSMG_RHOPA ;
DR   Q21CM2, RSMG_RHOPB ;  Q13E20, RSMG_RHOPS ;  B3Q8A6, RSMG_RHOPT ;
DR   Q2RN75, RSMG_RHORT ;  A3PNS5, RSMG_RHOS1 ;  Q3IYH5, RSMG_RHOS4 ;
DR   A4WVY8, RSMG_RHOS5 ;  C3PM95, RSMG_RICAE ;  A8GM00, RSMG_RICAH ;
DR   A8GUR2, RSMG_RICB8 ;  Q1RGT2, RSMG_RICBR ;  Q92JI2, RSMG_RICCN ;
DR   Q4UN89, RSMG_RICFE ;  A8F0G4, RSMG_RICM5 ;  Q9ZE89, RSMG_RICPR ;
DR   B0BW04, RSMG_RICRO ;  A8GQL8, RSMG_RICRS ;  Q68XT1, RSMG_RICTY ;
DR   Q16CZ7, RSMG_ROSDO ;  A1AVB2, RSMG_RUTMC ;  Q21DG3, RSMG_SACD2 ;
DR   B5EZ06, RSMG_SALA4 ;  A9MJR0, RSMG_SALAR ;  Q57HX0, RSMG_SALCH ;
DR   B5FN43, RSMG_SALDC ;  B4TAY2, RSMG_SALHS ;  B4SYE1, RSMG_SALNS ;
DR   Q5PJX2, RSMG_SALPA ;  A9MXB7, RSMG_SALPB ;  B5BIP4, RSMG_SALPK ;
DR   B4TN41, RSMG_SALSV ;  P64238, RSMG_SALTI ;  P64237, RSMG_SALTY ;
DR   A8GLL1, RSMG_SERP5 ;  A1SBV0, RSMG_SHEAM ;  B8EDW0, RSMG_SHEB2 ;
DR   A3DAS4, RSMG_SHEB5 ;  A6WUK0, RSMG_SHEB8 ;  A9KX16, RSMG_SHEB9 ;
DR   Q12HP1, RSMG_SHEDO ;  Q07VT4, RSMG_SHEFN ;  B0TQG4, RSMG_SHEHH ;
DR   A3QJS0, RSMG_SHELP ;  Q8E8B0, RSMG_SHEON ;  A8HAH3, RSMG_SHEPA ;
DR   A4YCI8, RSMG_SHEPC ;  B8CVV5, RSMG_SHEPW ;  A0KR27, RSMG_SHESA ;
DR   A8G1X5, RSMG_SHESH ;  Q0HD69, RSMG_SHESM ;  Q0HPF1, RSMG_SHESR ;
DR   A1RQC0, RSMG_SHESW ;  B1KQ44, RSMG_SHEWM ;  B2TUN5, RSMG_SHIB3 ;
DR   Q31UN9, RSMG_SHIBS ;  Q329S9, RSMG_SHIDS ;  Q0SYT6, RSMG_SHIF8 ;
DR   Q83PJ7, RSMG_SHIFL ;  Q3YVP4, RSMG_SHISS ;  Q5LWF2, RSMG_SILPO ;
DR   Q1GCL8, RSMG_SILST ;  A6UEE7, RSMG_SINMW ;  Q2NQ94, RSMG_SODGM ;
DR   A9GCQ1, RSMG_SORC5 ;  Q1GP62, RSMG_SPHAL ;  A5VA84, RSMG_SPHWW ;
DR   B4SNP6, RSMG_STRM5 ;  B2FNF9, RSMG_STRMK ;  Q30TL7, RSMG_SULDN ;
DR   A6QC07, RSMG_SULNB ;  Q2LY85, RSMG_SYNAS ;  Q31DK9, RSMG_THICR ;
DR   Q3SF56, RSMG_THIDA ;  A1WGT3, RSMG_VEREI ;  A5F469, RSMG_VIBC3 ;
DR   Q9KNG5, RSMG_VIBCH ;  C3LSJ9, RSMG_VIBCM ;  Q5E1M7, RSMG_VIBF1 ;
DR   A7N0X5, RSMG_VIBHB ;  Q87K99, RSMG_VIBPA ;  B7VN06, RSMG_VIBSL ;
DR   Q8DDH8, RSMG_VIBVU ;  Q7MGH0, RSMG_VIBVY ;  Q7M9J8, RSMG_WOLSU ;
DR   Q8PF23, RSMG_XANAC ;  Q3BML8, RSMG_XANC5 ;  Q4UP54, RSMG_XANC8 ;
DR   B0RYS0, RSMG_XANCB ;  Q8P3N0, RSMG_XANCP ;  Q2NXD0, RSMG_XANOM ;
DR   B2SU21, RSMG_XANOP ;  Q5GU13, RSMG_XANOR ;  B2I4Q1, RSMG_XYLF2 ;
DR   Q9PC50, RSMG_XYLFA ;  Q87D24, RSMG_XYLFT ;  A1JTD7, RSMG_YERE8 ;
DR   A7FPE8, RSMG_YERP3 ;  Q1C087, RSMG_YERPA ;  B2K7J3, RSMG_YERPB ;
DR   Q8Z9R9, RSMG_YERPE ;  A9R5U7, RSMG_YERPG ;  Q1CCG7, RSMG_YERPN ;
DR   A4TSI5, RSMG_YERPP ;  Q663Q0, RSMG_YERPS ;  B1JR33, RSMG_YERPY ;
DR   Q5NL06, RSMG_ZYMMO ;
//
ID   2.1.1.171
DE   16S rRNA (guanine(966)-N(2))-methyltransferase.
AN   M(2)G966 methyltransferase.
CA   S-adenosyl-L-methionine + guanosine(966) in 16S rRNA = S-adenosyl-L-
CA   homocysteine + N(2)-methylguanosine(966) in 16S rRNA.
CC   -!- The enzyme efficiently methylates guanine(966) of the assembled 30S
CC       subunits in vitro.
CC   -!- Protein-free 16S rRNA is not a substrate for RsmD.
CC   -!- The enzyme specifically methylates guanine(966) at N(2) in 16S rRNA.
CC   -!- Formerly EC 2.1.1.52.
DR   P57136, RSMD_BUCAI ;  Q89B29, RSMD_BUCBP ;  P0ADY0, RSMD_ECOL6 ;
DR   P0ADX9, RSMD_ECOLI ;  P44869, RSMD_HAEIN ;
//
ID   2.1.1.172
DE   16S rRNA (guanine(1207)-N(2))-methyltransferase.
AN   M(2)G1207 methyltransferase.
CA   S-adenosyl-L-methionine + guanosine(1207) in 16S rRNA = S-adenosyl-L-
CA   homocysteine + N(2)-methylguanosine(1207) in 16S rRNA.
CC   -!- The enzyme reacts well with 30S subunits reconstituted from 16S RNA
CC       transcripts and 30S proteins but is almost inactive with the
CC       corresponding free RNA.
CC   -!- The enzyme specifically methylates guanine(1207) at N(2) in 16S rRNA.
CC   -!- Formerly EC 2.1.1.52.
DR   Q6FE96, RSMC_ACIAD ;  B7GWT8, RSMC_ACIB3 ;  B2HYF8, RSMC_ACIBC ;
DR   B0VRJ4, RSMC_ACIBS ;  A3M8J9, RSMC_ACIBT ;  B0V4Z1, RSMC_ACIBY ;
DR   A3N3U3, RSMC_ACTP2 ;  B3GZF1, RSMC_ACTP7 ;  B0BU33, RSMC_ACTPJ ;
DR   A6VMV4, RSMC_ACTSZ ;  A0KPP9, RSMC_AERHH ;  A4SIE3, RSMC_AERS4 ;
DR   Q0VP64, RSMC_ALCBS ;  B6EL06, RSMC_ALISL ;  B4S2L3, RSMC_ALTMD ;
DR   P57413, RSMC_BUCAI ;  Q8K9L5, RSMC_BUCAP ;  Q89AI2, RSMC_BUCBP ;
DR   Q057M1, RSMC_BUCCC ;  Q1QUF2, RSMC_CHRSD ;  A8ALZ1, RSMC_CITK8 ;
DR   Q47VN0, RSMC_COLP3 ;  A7ZVR0, RSMC_ECO24 ;  B7MNC1, RSMC_ECO45 ;
DR   B7LEL6, RSMC_ECO55 ;  Q8X510, RSMC_ECO57 ;  B5Z4Q2, RSMC_ECO5E ;
DR   B7NVD9, RSMC_ECO7I ;  B7MTB6, RSMC_ECO81 ;  B7LXT2, RSMC_ECO8A ;
DR   B1XFI0, RSMC_ECODH ;  A8A899, RSMC_ECOHS ;  A1AJP2, RSMC_ECOK1 ;
DR   Q0T8U3, RSMC_ECOL5 ;  Q8FA64, RSMC_ECOL6 ;  B1IS49, RSMC_ECOLC ;
DR   P39406, RSMC_ECOLI ;  B7NH38, RSMC_ECOLU ;  B6I2Q2, RSMC_ECOSE ;
DR   B1LEH4, RSMC_ECOSM ;  Q1R2D5, RSMC_ECOUT ;  A4W687, RSMC_ENT38 ;
DR   A7MGA7, RSMC_ENTS8 ;  Q6D984, RSMC_ERWCT ;  B2VH94, RSMC_ERWT9 ;
DR   B7LNK6, RSMC_ESCF3 ;  Q7VP87, RSMC_HAEDU ;  Q4QPN2, RSMC_HAEI8 ;
DR   A5UBC5, RSMC_HAEIE ;  A5UFI6, RSMC_HAEIG ;  P44453, RSMC_HAEIN ;
DR   Q2SJX3, RSMC_HAHCH ;  C4K8X0, RSMC_HAMD5 ;  Q5R049, RSMC_IDILO ;
DR   B5Y286, RSMC_KLEP3 ;  A6THY6, RSMC_KLEP7 ;  Q65S65, RSMC_MANSM ;
DR   A1U204, RSMC_MARAV ;  A6VRG3, RSMC_MARMS ;  Q9CM79, RSMC_PASMU ;
DR   Q7MZN0, RSMC_PHOLL ;  Q6LUS5, RSMC_PHOPR ;  B4EWW4, RSMC_PROMH ;
DR   Q48MR4, RSMC_PSE14 ;  Q15ZS7, RSMC_PSEA6 ;  A6VC20, RSMC_PSEA7 ;
DR   B7V0H2, RSMC_PSEA8 ;  Q02G49, RSMC_PSEAB ;  Q9HVG4, RSMC_PSEAE ;
DR   Q1IEU2, RSMC_PSEE4 ;  Q4K6D2, RSMC_PSEF5 ;  Q3ILJ2, RSMC_PSEHT ;
DR   A4XYJ7, RSMC_PSEMY ;  A5VYJ3, RSMC_PSEP1 ;  Q3K705, RSMC_PSEPF ;
DR   B0KNH3, RSMC_PSEPG ;  Q88PT7, RSMC_PSEPK ;  B1JEN3, RSMC_PSEPW ;
DR   Q887Y4, RSMC_PSESM ;  Q4ZXT0, RSMC_PSEU2 ;  A4VIL0, RSMC_PSEU5 ;
DR   A1SZ19, RSMC_PSYIN ;  B5F512, RSMC_SALA4 ;  A9MRB9, RSMC_SALAR ;
DR   Q57G51, RSMC_SALCH ;  B5FTB3, RSMC_SALDC ;  B5R2I6, RSMC_SALEP ;
DR   B5R9T9, RSMC_SALG2 ;  B4TGY8, RSMC_SALHS ;  B4T4F9, RSMC_SALNS ;
DR   Q5PK16, RSMC_SALPA ;  A9N7C4, RSMC_SALPB ;  B5BL07, RSMC_SALPK ;
DR   B4TU29, RSMC_SALSV ;  Q8Z0V2, RSMC_SALTI ;  Q8ZJW6, RSMC_SALTY ;
DR   A8G9G5, RSMC_SERP5 ;  A1S321, RSMC_SHEAM ;  A3D8E4, RSMC_SHEB5 ;
DR   A6WJH4, RSMC_SHEB8 ;  A9L1V0, RSMC_SHEB9 ;  Q12JX1, RSMC_SHEDO ;
DR   Q088B4, RSMC_SHEFN ;  B0TSU8, RSMC_SHEHH ;  A3QHZ8, RSMC_SHELP ;
DR   Q8EIL1, RSMC_SHEON ;  A8H038, RSMC_SHEPA ;  A4YA93, RSMC_SHEPC ;
DR   B8CUC9, RSMC_SHEPW ;  A0L0V1, RSMC_SHESA ;  A8G0F9, RSMC_SHESH ;
DR   Q0HMF0, RSMC_SHESM ;  Q0HRD8, RSMC_SHESR ;  A1RG35, RSMC_SHESW ;
DR   B1KHR8, RSMC_SHEWM ;  B2TZQ2, RSMC_SHIB3 ;  Q31SW8, RSMC_SHIBS ;
DR   Q327M6, RSMC_SHIDS ;  Q0SX40, RSMC_SHIF8 ;  Q820Z6, RSMC_SHIFL ;
DR   Q3YU23, RSMC_SHISS ;  Q2NW11, RSMC_SODGM ;  A5F942, RSMC_VIBC3 ;
DR   Q9KUA0, RSMC_VIBCH ;  Q5E2W4, RSMC_VIBF1 ;  B5FAM0, RSMC_VIBFM ;
DR   A7MUT5, RSMC_VIBHB ;  Q87LY1, RSMC_VIBPA ;  Q8DBY0, RSMC_VIBVU ;
DR   Q7MHY6, RSMC_VIBVY ;  A1JJ89, RSMC_YERE8 ;  A7FMI4, RSMC_YERP3 ;
DR   Q1C153, RSMC_YERPA ;  B2K3H9, RSMC_YERPB ;  Q7CG56, RSMC_YERPE ;
DR   A9R058, RSMC_YERPG ;  Q1CN00, RSMC_YERPN ;  A4TQK1, RSMC_YERPP ;
DR   Q66EW9, RSMC_YERPS ;  B1JL46, RSMC_YERPY ;
//
ID   2.1.1.173
DE   23S rRNA (guanine(2445)-N(2))-methyltransferase.
CA   S-adenosyl-L-methionine + guanosine(2445) in 23S rRNA = S-adenosyl-L-
CA   homocysteine + N(2)-methylguanosine(2445) in 23S rRNA.
CC   -!- The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are
CC       not a substrate.
CC   -!- The enzyme specifically methylates guanine(2445) at N(2) in 23S rRNA.
CC   -!- Formerly EC 2.1.1.52.
DR   Q6FCR7, RLML_ACIAD ;  B2HWX8, RLML_ACIBC ;  B0VLH0, RLML_ACIBS ;
DR   B0VAL5, RLML_ACIBY ;  A3MYD2, RLML_ACTP2 ;  B3GZQ0, RLML_ACTP7 ;
DR   B0BRL8, RLML_ACTPJ ;  A6VMR3, RLML_ACTSZ ;  A0KKK7, RLML_AERHH ;
DR   A4SME4, RLML_AERS4 ;  Q0VQU5, RLML_ALCBS ;  Q0A793, RLML_ALHEH ;
DR   B6ELD3, RLML_ALISL ;  Q1W3E0, RLML_ALLVD ;  B4RZ48, RLML_ALTMD ;
DR   P57444, RLML_BUCAI ;  Q8K9I4, RLML_BUCAP ;  B3PIL6, RLML_CELJU ;
DR   Q1QXV9, RLML_CHRSD ;  A8AID1, RLML_CITK8 ;  Q47Z09, RLML_COLP3 ;
DR   Q6AQA5, RLML_DESPS ;  A5EX48, RLML_DICNV ;  A7ZK52, RLML_ECO24 ;
DR   Q8XDB2, RLML_ECO57 ;  B5YT79, RLML_ECO5E ;  B1X8Q2, RLML_ECODH ;
DR   A7ZYQ0, RLML_ECOHS ;  A1A9L8, RLML_ECOK1 ;  Q0TJB3, RLML_ECOL5 ;
DR   Q8FJ88, RLML_ECOL6 ;  B1IVY4, RLML_ECOLC ;  P75864, RLML_ECOLI ;
DR   B1LJR4, RLML_ECOSM ;  Q1RDR6, RLML_ECOUT ;  A4W8W0, RLML_ENT38 ;
DR   A7MEX5, RLML_ENTS8 ;  Q6D459, RLML_ERWCT ;  B2VDF6, RLML_ERWT9 ;
DR   B0U0U4, RLML_FRAP2 ;  Q14HS5, RLML_FRAT1 ;  A7NCY2, RLML_FRATF ;
DR   Q2A2U4, RLML_FRATH ;  B2SGG3, RLML_FRATM ;  A0Q621, RLML_FRATN ;
DR   Q0BLC3, RLML_FRATO ;  Q5NGC3, RLML_FRATT ;  A4IXN4, RLML_FRATW ;
DR   Q7VP04, RLML_HAEDU ;  Q4QP66, RLML_HAEI8 ;  A5UB28, RLML_HAEIE ;
DR   A5UFS2, RLML_HAEIG ;  P44524, RLML_HAEIN ;  Q0I4C6, RLML_HAES1 ;
DR   B0UUM5, RLML_HAES2 ;  Q2SCH1, RLML_HAHCH ;  Q5QX63, RLML_IDILO ;
DR   B5XY56, RLML_KLEP3 ;  A6T742, RLML_KLEP7 ;  Q5X969, RLML_LEGPA ;
DR   A5I9H3, RLML_LEGPC ;  Q5ZZI8, RLML_LEGPH ;  Q5X0J6, RLML_LEGPL ;
DR   A0L8B5, RLML_MAGSM ;  Q65UK6, RLML_MANSM ;  A1TZG2, RLML_MARAV ;
DR   A6VW36, RLML_MARMS ;  Q60AX5, RLML_METCA ;  Q9CNW9, RLML_PASMU ;
DR   Q3A2U5, RLML_PELCD ;  Q7N612, RLML_PHOLL ;  Q6LRA0, RLML_PHOPR ;
DR   B4EVC6, RLML_PROMH ;  Q48JX8, RLML_PSE14 ;  Q15UB5, RLML_PSEA6 ;
DR   A6V328, RLML_PSEA7 ;  Q9HZG0, RLML_PSEAE ;  Q1ICL2, RLML_PSEE4 ;
DR   Q4KFI6, RLML_PSEF5 ;  Q3IGZ3, RLML_PSEHT ;  A4XWP8, RLML_PSEMY ;
DR   A5W6K7, RLML_PSEP1 ;  Q3KFC5, RLML_PSEPF ;  B0KG92, RLML_PSEPG ;
DR   Q88L39, RLML_PSEPK ;  B1J5B7, RLML_PSEPW ;  Q883N9, RLML_PSESM ;
DR   Q4ZUM1, RLML_PSEU2 ;  A4VM39, RLML_PSEU5 ;  Q4FTN9, RLML_PSYA2 ;
DR   Q1QCP8, RLML_PSYCK ;  A1SX09, RLML_PSYIN ;  A5WGC0, RLML_PSYWF ;
DR   Q21JW7, RLML_SACD2 ;  B5F1U5, RLML_SALA4 ;  A9MHU0, RLML_SALAR ;
DR   Q57QU1, RLML_SALCH ;  B5FQZ1, RLML_SALDC ;  B5QZF1, RLML_SALEP ;
DR   B5R6B4, RLML_SALG2 ;  B4TDY8, RLML_SALHS ;  B4T1Z1, RLML_SALNS ;
DR   Q5PGE3, RLML_SALPA ;  A9N6Y0, RLML_SALPB ;  B5BBL9, RLML_SALPK ;
DR   B4TRX1, RLML_SALSV ;  Q8Z7S6, RLML_SALTI ;  Q8ZQ73, RLML_SALTY ;
DR   A8GCK7, RLML_SERP5 ;  A1S601, RLML_SHEAM ;  A3D5Q0, RLML_SHEB5 ;
DR   A6WPK6, RLML_SHEB8 ;  A9L591, RLML_SHEB9 ;  Q12LC6, RLML_SHEDO ;
DR   Q07ZR3, RLML_SHEFN ;  B0TIX7, RLML_SHEHH ;  A3QDY0, RLML_SHELP ;
DR   Q8EFW4, RLML_SHEON ;  A8H3Y1, RLML_SHEPA ;  A4Y5X4, RLML_SHEPC ;
DR   A0KVL6, RLML_SHESA ;  A8FW59, RLML_SHESH ;  Q0HJZ9, RLML_SHESM ;
DR   Q0HWA0, RLML_SHESR ;  A1RKM2, RLML_SHESW ;  B1KDN0, RLML_SHEWM ;
DR   B2TUD1, RLML_SHIB3 ;  Q31YL1, RLML_SHIBS ;  Q32HV8, RLML_SHIDS ;
DR   Q0T686, RLML_SHIF8 ;  Q83RX5, RLML_SHIFL ;  Q3Z3H3, RLML_SHISS ;
DR   Q2NU80, RLML_SODGM ;  B4SQ79, RLML_STRM5 ;  B2FJ58, RLML_STRMK ;
DR   Q31IC8, RLML_THICR ;  A5F836, RLML_VIBC3 ;  Q9KRZ5, RLML_VIBCH ;
DR   Q5E5B4, RLML_VIBF1 ;  B5FE19, RLML_VIBFM ;  A7N0M8, RLML_VIBHB ;
DR   Q87PC0, RLML_VIBPA ;  Q7MKX1, RLML_VIBVY ;  Q8PM40, RLML_XANAC ;
DR   Q3BV47, RLML_XANC5 ;  Q4UT85, RLML_XANC8 ;  B0RV07, RLML_XANCB ;
DR   Q8PAE0, RLML_XANCP ;  Q2P309, RLML_XANOM ;  B2SIS8, RLML_XANOP ;
DR   Q5H029, RLML_XANOR ;  B2IA87, RLML_XYLF2 ;  Q9PA69, RLML_XYLFA ;
DR   B0U5Z5, RLML_XYLFM ;  Q87A16, RLML_XYLFT ;  A1JMQ6, RLML_YERE8 ;
DR   A7FJT9, RLML_YERP3 ;  Q1CA41, RLML_YERPA ;  B2JYS1, RLML_YERPB ;
DR   Q7CHK7, RLML_YERPE ;  A9R7L5, RLML_YERPG ;  Q1CGJ3, RLML_YERPN ;
DR   A4TMZ0, RLML_YERPP ;  Q66CG1, RLML_YERPS ;  B1JQR7, RLML_YERPY ;
//
ID   2.1.1.174
DE   23S rRNA (guanine(1835)-N(2))-methyltransferase.
AN   Ribosomal RNA large subunit methyltransferase G.
CA   S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = S-adenosyl-L-
CA   homocysteine + N(2)-methylguanosine(1835) in 23S rRNA.
CC   -!- The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are
CC       not a substrate.
CC   -!- The enzyme specifically methylates guanine(1835) at N(2) in 23S rRNA.
CC   -!- Formerly EC 2.1.1.52.
DR   A0KHC4, RLMG_AERHH ;  A4SQM2, RLMG_AERS4 ;  Q0VPK2, RLMG_ALCBS ;
DR   B6EIC1, RLMG_ALISL ;  B4RZB4, RLMG_ALTMD ;  A8APY0, RLMG_CITK8 ;
DR   Q488Q3, RLMG_COLP3 ;  A7ZRW7, RLMG_ECO24 ;  Q8XAK8, RLMG_ECO57 ;
DR   B5YRC4, RLMG_ECO5E ;  B1XG88, RLMG_ECODH ;  A8A4P1, RLMG_ECOHS ;
DR   A1AG02, RLMG_ECOK1 ;  Q0TD22, RLMG_ECOL5 ;  Q8FDE5, RLMG_ECOL6 ;
DR   B1IRN3, RLMG_ECOLC ;  P42596, RLMG_ECOLI ;  B1LFI2, RLMG_ECOSM ;
DR   Q1R6P6, RLMG_ECOUT ;  A4WER8, RLMG_ENT38 ;  A7MIS8, RLMG_ENTS8 ;
DR   Q6D9G1, RLMG_ERWCT ;  B2VDD5, RLMG_ERWT9 ;  B5XTX7, RLMG_KLEP3 ;
DR   A6TEC2, RLMG_KLEP7 ;  A0L9S5, RLMG_MAGSM ;  Q6LTZ3, RLMG_PHOPR ;
DR   Q48DT7, RLMG_PSE14 ;  Q15YR1, RLMG_PSEA6 ;  A6VC08, RLMG_PSEA7 ;
DR   Q02G60, RLMG_PSEAB ;  Q9HVH4, RLMG_PSEAE ;  Q1I4K4, RLMG_PSEE4 ;
DR   Q4K5Q4, RLMG_PSEF5 ;  Q3IHQ6, RLMG_PSEHT ;  A4XQA3, RLMG_PSEMY ;
DR   A5W920, RLMG_PSEP1 ;  Q3K6H7, RLMG_PSEPF ;  B0KHQ8, RLMG_PSEPG ;
DR   Q88E20, RLMG_PSEPK ;  B1J2W7, RLMG_PSEPW ;  Q0EDR2, RLMG_PSESH ;
DR   Q87WA9, RLMG_PSESM ;  Q4ZNG3, RLMG_PSEU2 ;  A4VI28, RLMG_PSEU5 ;
DR   A1SX22, RLMG_PSYIN ;  B5F6B6, RLMG_SALA4 ;  A9MPU2, RLMG_SALAR ;
DR   Q57JN9, RLMG_SALCH ;  B5FHV5, RLMG_SALDC ;  B5QZ55, RLMG_SALEP ;
DR   B5REH7, RLMG_SALG2 ;  B4TIU8, RLMG_SALHS ;  B4T690, RLMG_SALNS ;
DR   Q5PC93, RLMG_SALPA ;  A9N601, RLMG_SALPB ;  B5BG31, RLMG_SALPK ;
DR   B4TVV4, RLMG_SALSV ;  Q8Z3L8, RLMG_SALTI ;  Q8ZLX5, RLMG_SALTY ;
DR   A8GJW6, RLMG_SERP5 ;  A1S8P4, RLMG_SHEAM ;  A3D130, RLMG_SHEB5 ;
DR   A6WRY2, RLMG_SHEB8 ;  A9L0V0, RLMG_SHEB9 ;  Q12K11, RLMG_SHEDO ;
DR   Q07YH6, RLMG_SHEFN ;  B0TR07, RLMG_SHEHH ;  A3QH04, RLMG_SHELP ;
DR   Q8EHW5, RLMG_SHEON ;  A8H786, RLMG_SHEPA ;  A4Y3Y0, RLMG_SHEPC ;
DR   A0KTP8, RLMG_SHESA ;  A8FYW7, RLMG_SHESH ;  Q0HLQ7, RLMG_SHESM ;
DR   Q0HY38, RLMG_SHESR ;  A1RN12, RLMG_SHESW ;  B1KD54, RLMG_SHEWM ;
DR   B2U1T3, RLMG_SHIB3 ;  Q31WU9, RLMG_SHIBS ;  Q32BN8, RLMG_SHIDS ;
DR   Q0T0I4, RLMG_SHIF8 ;  Q821A5, RLMG_SHIFL ;  Q3YXQ6, RLMG_SHISS ;
DR   Q82N59, RLMG_STRAW ;  Q9K3L9, RLMG_STRCO ;  B1VMX8, RLMG_STRGG ;
DR   A5F5X3, RLMG_VIBC3 ;  Q9KPR9, RLMG_VIBCH ;  Q5E6X8, RLMG_VIBF1 ;
DR   B5FBH8, RLMG_VIBFM ;  A7N1U8, RLMG_VIBHB ;  Q87MA4, RLMG_VIBPA ;
DR   B7VKD0, RLMG_VIBSL ;  Q8DBJ8, RLMG_VIBVU ;  Q7MIC5, RLMG_VIBVY ;
DR   A1JR10, RLMG_YERE8 ;  A7FE15, RLMG_YERP3 ;  Q1C310, RLMG_YERPA ;
DR   B2K3B8, RLMG_YERPB ;  Q0WJ78, RLMG_YERPE ;  A9R1N3, RLMG_YERPG ;
DR   Q1CMJ1, RLMG_YERPN ;  A4THM8, RLMG_YERPP ;  Q665P6, RLMG_YERPS ;
DR   B1JLA4, RLMG_YERPY ;
//
ID   2.1.1.175
DE   Tricin synthase.
CA   2 S-adenosyl-L-methionine + tricetin = 2 S-adenosyl-L-homocysteine +
CA   3',5'-O-dimethyltricetin.
CC   -!- The enzymes from Oryza sativa (ROMT-15 and ROMT-17) catalyzes the
CC       stepwise methylation of tricetin to its 3'-mono- and 3',5'-dimethyl
CC       ethers.
CC   -!- In contrast with the wheat enzyme (EC 2.1.1.167, tricetin 3',4',5'-O-
CC       trimethyltransferase), tricetin dimethyl ether is not converted to
CC       its 3',4',5'-trimethylated ether derivative.
CC   -!- The enzymes from Hordeum vulgare (HvOMT1) and from Zea mays (ZmOMT1)
CC       form the 3',5'-dimethyl derivative as the major product.
//
ID   2.1.1.176
DE   16S rRNA (cytosine(967)-C(5))-methyltransferase.
CA   S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-
CA   homocysteine + 5-methylcytosine(967) in 16S rRNA.
CC   -!- The enzyme specifically methylates cytosine(967) at C(5) in 16S rRNA.
DR   A8AQI3, RSMB_CITK8 ;  A7ZSH7, RSMB_ECO24 ;  B7UK12, RSMB_ECO27 ;
DR   B7MCQ4, RSMB_ECO45 ;  B7LHZ0, RSMB_ECO55 ;  Q8XEE5, RSMB_ECO57 ;
DR   B5YT08, RSMB_ECO5E ;  B7NLK8, RSMB_ECO7I ;  B7N0S9, RSMB_ECO81 ;
DR   B7M0Z4, RSMB_ECO8A ;  C4ZUE3, RSMB_ECOBW ;  B1X6E1, RSMB_ECODH ;
DR   A8A593, RSMB_ECOHS ;  A1AGI0, RSMB_ECOK1 ;  Q0TCH3, RSMB_ECOL5 ;
DR   Q8FD12, RSMB_ECOL6 ;  B1IQ11, RSMB_ECOLC ;  P36929, RSMB_ECOLI ;
DR   B7NDR0, RSMB_ECOLU ;  B6I202, RSMB_ECOSE ;  B1LGP5, RSMB_ECOSM ;
DR   Q1R644, RSMB_ECOUT ;  A4WF97, RSMB_ENT38 ;  A7MPE7, RSMB_ENTS8 ;
DR   Q6D000, RSMB_ERWCT ;  B2VK95, RSMB_ERWT9 ;  B7LRQ5, RSMB_ESCF3 ;
DR   Q7VKC4, RSMB_HAEDU ;  P44788, RSMB_HAEIN ;  B5XNC2, RSMB_KLEP3 ;
DR   A6TEU2, RSMB_KLEP7 ;  Q9CKP7, RSMB_PASMU ;  C6DFR7, RSMB_PECCP ;
DR   Q7MYI0, RSMB_PHOLL ;  B4F1L5, RSMB_PROMH ;  Q9I7A9, RSMB_PSEAE ;
DR   Q88RR3, RSMB_PSEPK ;  Q88B41, RSMB_PSESM ;  B5F7R5, RSMB_SALA4 ;
DR   A9MN78, RSMB_SALAR ;  Q57J62, RSMB_SALCH ;  B5FJI4, RSMB_SALDC ;
DR   B5R1E5, RSMB_SALEP ;  B5RH47, RSMB_SALG2 ;  B4TJX9, RSMB_SALHS ;
DR   B4SUR0, RSMB_SALNS ;  Q5PIT6, RSMB_SALPA ;  A9N8B3, RSMB_SALPB ;
DR   C0PZV1, RSMB_SALPC ;  B5BGV5, RSMB_SALPK ;  B4TXB2, RSMB_SALSV ;
DR   Q8Z1X1, RSMB_SALTI ;  Q8ZLM5, RSMB_SALTY ;  A8GKG7, RSMB_SERP5 ;
DR   Q8EKR0, RSMB_SHEON ;  B2U2Q6, RSMB_SHIB3 ;  Q31VY8, RSMB_SHIBS ;
DR   Q32B61, RSMB_SHIDS ;  Q0T014, RSMB_SHIF8 ;  Q7UBD3, RSMB_SHIFL ;
DR   Q3YWX1, RSMB_SHISS ;  Q2NQQ2, RSMB_SODGM ;  Q9KVU5, RSMB_VIBCH ;
DR   Q87KD3, RSMB_VIBPA ;  Q8DDE5, RSMB_VIBVU ;  Q7MGK4, RSMB_VIBVY ;
DR   Q8PG22, RSMB_XANAC ;  Q8P4G1, RSMB_XANCP ;  Q9PEV0, RSMB_XYLFA ;
DR   Q87AR1, RSMB_XYLFT ;  A1JRZ3, RSMB_YERE8 ;  A7FNK4, RSMB_YERP3 ;
DR   Q1C2X7, RSMB_YERPA ;  B2K506, RSMB_YERPB ;  Q8ZJ81, RSMB_YERPE ;
DR   A9R925, RSMB_YERPG ;  Q1CCX4, RSMB_YERPN ;  A4TH21, RSMB_YERPP ;
DR   Q664V2, RSMB_YERPS ;  B1JJH6, RSMB_YERPY ;
//
ID   2.1.1.177
DE   23S rRNA (pseudouridine(1915)-N(3))-methyltransferase.
AN   Pseudouridine methyltransferase.
AN   Psi(1915)-specific methyltransferase.
AN   rRNA large subunit methyltransferase H.
CA   S-adenosyl-L-methionine + pseudouridine(1915) in 23S rRNA = S-adenosyl-L-
CA   homocysteine + N(3)-methylpseudouridine(1915) in 23S rRNA.
CC   -!- YbeA does not methylate uridine at position 1915.
//
ID   2.1.1.178
DE   16S rRNA (cytosine(1407)-C(5))-methyltransferase.
CA   S-adenosyl-L-methionine + cytosine(1407) in 16S rRNA = S-adenosyl-L-
CA   homocysteine + 5-methylcytosine(1407) in 16S rRNA.
CC   -!- The enzyme specifically methylates cytosine(1407) at C(5) in 16S
CC       rRNA.
DR   A0KKI5, RSMF_AERHH ;  A4SMI9, RSMF_AERS4 ;  B6ELC0, RSMF_ALISL ;
DR   A8AFL6, RSMF_CITK8 ;  A7ZMV8, RSMF_ECO24 ;  B7USL2, RSMF_ECO27 ;
DR   B7MBP2, RSMF_ECO45 ;  B7L7N7, RSMF_ECO55 ;  Q8XCL9, RSMF_ECO57 ;
DR   B5YQX9, RSMF_ECO5E ;  B7NS84, RSMF_ECO7I ;  B7MVW5, RSMF_ECO81 ;
DR   B7M2B1, RSMF_ECO8A ;  C4ZZJ2, RSMF_ECOBW ;  B1XHA3, RSMF_ECODH ;
DR   A8A133, RSMF_ECOHS ;  A1AC00, RSMF_ECOK1 ;  Q0TGZ7, RSMF_ECOL5 ;
DR   Q8FGS9, RSMF_ECOL6 ;  B1J0Q3, RSMF_ECOLC ;  P76273, RSMF_ECOLI ;
DR   B7NBI3, RSMF_ECOLU ;  B6IBR3, RSMF_ECOSE ;  B1LD37, RSMF_ECOSM ;
DR   Q1RAV2, RSMF_ECOUT ;  A4WBJ4, RSMF_ENT38 ;  A7MKH5, RSMF_ENTS8 ;
DR   Q6D4C8, RSMF_ERWCT ;  B2VJ83, RSMF_ERWT9 ;  B7LPL0, RSMF_ESCF3 ;
DR   B5XQ35, RSMF_KLEP3 ;  A6TB06, RSMF_KLEP7 ;  C6DFU6, RSMF_PECCP ;
DR   Q6LQU5, RSMF_PHOPR ;  Q3IHA0, RSMF_PSEHT ;  A1SWV0, RSMF_PSYIN ;
DR   B5F3P3, RSMF_SALA4 ;  A9MNH4, RSMF_SALAR ;  Q57NF9, RSMF_SALCH ;
DR   B5FTI4, RSMF_SALDC ;  B5R2S1, RSMF_SALEP ;  B5R8V2, RSMF_SALG2 ;
DR   B4TKI0, RSMF_SALHS ;  B4SV89, RSMF_SALNS ;  Q5PHN5, RSMF_SALPA ;
DR   A9MV57, RSMF_SALPB ;  C0Q2Y5, RSMF_SALPC ;  B5BHA6, RSMF_SALPK ;
DR   B4TY18, RSMF_SALSV ;  Q8Z662, RSMF_SALTI ;  Q8ZNZ2, RSMF_SALTY ;
DR   A8GDM6, RSMF_SERP5 ;  A1S788, RSMF_SHEAM ;  B8E968, RSMF_SHEB2 ;
DR   A3D5D5, RSMF_SHEB5 ;  A6WP46, RSMF_SHEB8 ;  A9L4E6, RSMF_SHEB9 ;
DR   Q12MJ8, RSMF_SHEDO ;  Q081I3, RSMF_SHEFN ;  B0TIZ6, RSMF_SHEHH ;
DR   A3QDA2, RSMF_SHELP ;  Q8EDY2, RSMF_SHEON ;  A8H3W2, RSMF_SHEPA ;
DR   A4Y7J8, RSMF_SHEPC ;  B8CPH7, RSMF_SHEPW ;  A0KW34, RSMF_SHESA ;
DR   A8FWM8, RSMF_SHESH ;  Q0HJM6, RSMF_SHESM ;  Q0HVX2, RSMF_SHESR ;
DR   A1RIZ0, RSMF_SHESW ;  B1KQN1, RSMF_SHEWM ;  B2U477, RSMF_SHIB3 ;
DR   Q321Y0, RSMF_SHIBS ;  Q32F19, RSMF_SHIDS ;  Q0T529, RSMF_SHIF8 ;
DR   Q83RJ3, RSMF_SHIFL ;  Q3Z2H4, RSMF_SHISS ;  Q9KRY1, RSMF_VIBCH ;
DR   C3LMI5, RSMF_VIBCM ;  Q5E5C7, RSMF_VIBF1 ;  B5FE06, RSMF_VIBFM ;
DR   A7N0K6, RSMF_VIBHB ;  Q87PA5, RSMF_VIBPA ;  B7VNJ8, RSMF_VIBSL ;
DR   Q8D9F3, RSMF_VIBVU ;  Q7MKY6, RSMF_VIBVY ;
//
ID   2.1.1.179
DE   16S rRNA (guanine(1405)-C(7))-methyltransferase.
AN   Sisomicin-gentamicin methyltransferase.
CA   S-adenosyl-L-methionine + guanine(1405) in 16S rRNA = S-adenosyl-L-
CA   homocysteine + 7-methylguanine(1405) in 16S rRNA.
CC   -!- The enzyme specifically methylates guanine(1405) at C(7) in 16S rRNA.
CC   -!- The enzyme from the antibiotic-producing bacterium Micromonospora
CC       zionensis methylates guanine(1405) in 16S rRNA to 7-methylguanine,
CC       thereby rendering the ribosome resistant to 4,6-disubstituted
CC       deoxystreptamine aminoglycosides, which include gentamicins and
CC       kanamycins.
//
ID   2.1.1.180
DE   16S rRNA (adenine(1408)-N(1))-methyltransferase.
CA   S-adenosyl-L-methionine + adenine(1408) in 16S rRNA = S-adenosyl-L-
CA   homocysteine + N(1)-methyladenine(1408) in 16S rRNA.
CC   -!- The enzyme provides a panaminoglycoside-resistant nature through
CC       interference with the binding of aminoglycosides toward the A site of
CC       16S rRNA through N(1)-methylation at position adenine(1408).
//
ID   2.1.1.181
DE   23S rRNA (adenine(1618)-N(6))-methyltransferase.
AN   rRNA large subunit methyltransferase F.
CA   S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-
CA   homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA.
CC   -!- The recombinant YbiN protein is able to methylate partially
CC       deproteinized 50 S ribosomal subunit, but neither the completely
CC       assembled 50 S subunits nor completely deproteinized 23 S rRNA.
CC   -!- Formerly EC 2.1.1.48.
PR   PROSITE; PDOC00871;
DR   A0KHV5, RLMF_AERHH ;  A4SKI2, RLMF_AERS4 ;  C1DPF6, RLMF_AZOVD ;
DR   Q5LBA7, RLMF_BACFN ;  Q64RQ5, RLMF_BACFR ;  Q89YP0, RLMF_BACTN ;
DR   A8AIX5, RLMF_CITK8 ;  Q482M9, RLMF_COLP3 ;  Q11XA9, RLMF_CYTH3 ;
DR   Q47C26, RLMF_DECAR ;  Q6ANQ6, RLMF_DESPS ;  A7ZJM2, RLMF_ECO24 ;
DR   B7UM03, RLMF_ECO27 ;  B7MGR5, RLMF_ECO45 ;  B7LC90, RLMF_ECO55 ;
DR   Q8X7W6, RLMF_ECO57 ;  B5YS99, RLMF_ECO5E ;  B7NNN9, RLMF_ECO7I ;
DR   B7MQR1, RLMF_ECO81 ;  B7M782, RLMF_ECO8A ;  C4ZXX9, RLMF_ECOBW ;
DR   B1X7D7, RLMF_ECODH ;  A7ZY64, RLMF_ECOHS ;  A1A947, RLMF_ECOK1 ;
DR   Q0TJP1, RLMF_ECOL5 ;  Q8FJM4, RLMF_ECOL6 ;  B1IXG1, RLMF_ECOLC ;
DR   P75782, RLMF_ECOLI ;  B7NAA7, RLMF_ECOLU ;  B1LM99, RLMF_ECOSM ;
DR   Q1REB8, RLMF_ECOUT ;  A4W8E5, RLMF_ENT38 ;  A7MEZ1, RLMF_ENTS8 ;
DR   Q6D958, RLMF_ERWCT ;  B7LJV2, RLMF_ESCF3 ;  A5FHX5, RLMF_FLAJ1 ;
DR   A6H0G2, RLMF_FLAPJ ;  A0M4S0, RLMF_GRAFK ;  B5XYT7, RLMF_KLEP3 ;
DR   A6T6Q1, RLMF_KLEP7 ;  A6W2M9, RLMF_MARMS ;  Q1H501, RLMF_METFK ;
DR   C6D8Y7, RLMF_PECCP ;  Q6LIW6, RLMF_PHOPR ;  Q48MF3, RLMF_PSE14 ;
DR   Q15VI3, RLMF_PSEA6 ;  A6V0S3, RLMF_PSEA7 ;  B7UVS7, RLMF_PSEA8 ;
DR   Q02RZ9, RLMF_PSEAB ;  Q9HXG4, RLMF_PSEAE ;  Q1I5F5, RLMF_PSEE4 ;
DR   Q4KHU0, RLMF_PSEF5 ;  C3K6G1, RLMF_PSEFS ;  Q3IBW7, RLMF_PSEHT ;
DR   A4XY67, RLMF_PSEMY ;  A5VZ65, RLMF_PSEP1 ;  Q3KHM8, RLMF_PSEPF ;
DR   B0KQK4, RLMF_PSEPG ;  Q88P77, RLMF_PSEPK ;  B1JBB3, RLMF_PSEPW ;
DR   Q887M4, RLMF_PSESM ;  Q4ZXI1, RLMF_PSEU2 ;  A4VP05, RLMF_PSEU5 ;
DR   Q4FVS6, RLMF_PSYA2 ;  Q1QEW1, RLMF_PSYCK ;  A1SSI8, RLMF_PSYIN ;
DR   A5WBC6, RLMF_PSYWF ;  Q21P11, RLMF_SACD2 ;  B5F0A4, RLMF_SALA4 ;
DR   A9MIS5, RLMF_SALAR ;  B5FP91, RLMF_SALDC ;  B5QXT1, RLMF_SALEP ;
DR   B5R792, RLMF_SALG2 ;  B4TC80, RLMF_SALHS ;  B4T083, RLMF_SALNS ;
DR   Q5PG24, RLMF_SALPA ;  A9MSU1, RLMF_SALPB ;  B5BC01, RLMF_SALPK ;
DR   B4TQW9, RLMF_SALSV ;  Q8ZQN4, RLMF_SALTY ;  A8GBT4, RLMF_SERP5 ;
DR   A1SBR7, RLMF_SHEAM ;  B8E3W0, RLMF_SHEB2 ;  A3DAC9, RLMF_SHEB5 ;
DR   A6WHK9, RLMF_SHEB8 ;  A9KVB0, RLMF_SHEB9 ;  Q12T32, RLMF_SHEDO ;
DR   Q08A02, RLMF_SHEFN ;  B0TM80, RLMF_SHEHH ;  A3QJF9, RLMF_SHELP ;
DR   Q8EKF9, RLMF_SHEON ;  A8HA69, RLMF_SHEPA ;  A4Y1N1, RLMF_SHEPC ;
DR   A0KRF2, RLMF_SHESA ;  A8G1Q8, RLMF_SHESH ;  Q0HP08, RLMF_SHESM ;
DR   Q0I0H7, RLMF_SHESR ;  A1RQ03, RLMF_SHESW ;  B1KP42, RLMF_SHEWM ;
DR   B2TVC2, RLMF_SHIB3 ;  Q323Y7, RLMF_SHIBS ;  Q32I85, RLMF_SHIDS ;
DR   Q0T6F4, RLMF_SHIF8 ;  Q83LU4, RLMF_SHIFL ;  Q3Z3X8, RLMF_SHISS ;
DR   A5F7R5, RLMF_VIBC3 ;  Q9KRM2, RLMF_VIBCH ;  C3LMU1, RLMF_VIBCM ;
DR   Q5DYC3, RLMF_VIBF1 ;  B5EVS5, RLMF_VIBFM ;  A7N060, RLMF_VIBHB ;
DR   Q87Q26, RLMF_VIBPA ;  Q8D935, RLMF_VIBVU ;  Q7MLD9, RLMF_VIBVY ;
DR   A1JU40, RLMF_YERE8 ;  A7FGU1, RLMF_YERP3 ;  Q1C6E5, RLMF_YERPA ;
DR   B2K7Y6, RLMF_YERPB ;  Q7CJ72, RLMF_YERPE ;  A9R6I2, RLMF_YERPG ;
DR   Q1CHT7, RLMF_YERPN ;  A4TM00, RLMF_YERPP ;  Q669D4, RLMF_YERPS ;
DR   B1JH95, RLMF_YERPY ;
//
ID   2.1.1.182
DE   16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase.
CA   4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA =
CA   4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)-
CA   dimethyladenine(1519) in 16S rRNA.
CC   -!- KsgA introduces the most highly conserved ribosomal RNA modification,
CC       the dimethylation of adenine(1518) and adenine(1519) in 16S rRNA.
CC   -!- Strains lacking the methylase are resistant to kasugamycin.
CC   -!- Formerly EC 2.1.1.48.
DR   B0CC89, RSMA_ACAM1 ;  A1TWF5, RSMA_ACIAC ;  Q6F8A0, RSMA_ACIAD ;
DR   Q1ILA1, RSMA_ACIBL ;  A0LR93, RSMA_ACIC1 ;  C1F127, RSMA_ACIC5 ;
DR   B9MIF6, RSMA_ACIET ;  B7J3R3, RSMA_ACIF2 ;  B5EL84, RSMA_ACIF5 ;
DR   A1WD86, RSMA_ACISJ ;  A3MZB7, RSMA_ACTP2 ;  B3H0R3, RSMA_ACTP7 ;
DR   B0BTQ4, RSMA_ACTPJ ;  A0KGT8, RSMA_AERHH ;  Q8UGD5, RSMA_AGRT5 ;
DR   B9JUV4, RSMA_AGRVS ;  Q0VMV2, RSMA_ALCBS ;  B6EL48, RSMA_ALISL ;
DR   A6TJK9, RSMA_ALKMQ ;  A8MK56, RSMA_ALKOO ;  B8J7H0, RSMA_ANAD2 ;
DR   Q2IFT9, RSMA_ANADE ;  B9KIG4, RSMA_ANAMF ;  Q5PAV9, RSMA_ANAMM ;
DR   Q2GK91, RSMA_ANAPZ ;  B4UDZ6, RSMA_ANASK ;  Q3M3F3, RSMA_ANAVT ;
DR   B7GFH0, RSMA_ANOFW ;  O67680, RSMA_AQUAE ;  A8EQW4, RSMA_ARCB4 ;
DR   Q5P7J1, RSMA_AROAE ;  A1R4F7, RSMA_ARTAT ;  A0JU87, RSMA_ARTS2 ;
DR   Q2NIH8, RSMA_AYWBP ;  A8HVI9, RSMA_AZOC5 ;  C3P9I6, RSMA_BACAA ;
DR   C3LJ13, RSMA_BACAC ;  A0R8B4, RSMA_BACAH ;  Q81W00, RSMA_BACAN ;
DR   B7JK47, RSMA_BACC0 ;  Q73FG7, RSMA_BACC1 ;  B7ISV1, RSMA_BACC2 ;
DR   C1ESX0, RSMA_BACC3 ;  B7HIK9, RSMA_BACC4 ;  B7HPV2, RSMA_BACC7 ;
DR   A7GJV3, RSMA_BACCN ;  B9IZC4, RSMA_BACCQ ;  Q81JA5, RSMA_BACCR ;
DR   Q63HJ1, RSMA_BACCZ ;  Q5LHC9, RSMA_BACFN ;  Q64Y97, RSMA_BACFR ;
DR   Q9KGK4, RSMA_BACHD ;  Q6HPX5, RSMA_BACHK ;  Q65PH9, RSMA_BACLD ;
DR   A8F909, RSMA_BACP2 ;  Q5WLW2, RSMA_BACSK ;  P37468, RSMA_BACSU ;
DR   Q8A0H8, RSMA_BACTN ;  A6L1N4, RSMA_BACV8 ;  A9VN54, RSMA_BACWK ;
DR   A1US65, RSMA_BARBK ;  Q6G438, RSMA_BARHE ;  Q6G052, RSMA_BARQU ;
DR   A9IRW8, RSMA_BART1 ;  Q1LSS2, RSMA_BAUCH ;  Q6MQ47, RSMA_BDEBA ;
DR   A1A3W3, RSMA_BIFAA ;  B3DP38, RSMA_BIFLD ;  Q8G6I3, RSMA_BIFLO ;
DR   B7GPE3, RSMA_BIFLS ;  Q7VQK3, RSMA_BLOFL ;  Q493R7, RSMA_BLOPB ;
DR   Q2KXA2, RSMA_BORA1 ;  Q0SMR8, RSMA_BORAP ;  Q7WG20, RSMA_BORBR ;
DR   O51536, RSMA_BORBU ;  B7J2F3, RSMA_BORBZ ;  Q660T2, RSMA_BORGA ;
DR   Q7W4J6, RSMA_BORPA ;  A9I5F2, RSMA_BORPD ;  Q7VU11, RSMA_BORPE ;
DR   Q89MU0, RSMA_BRAJA ;  A5EIA8, RSMA_BRASB ;  A4YT90, RSMA_BRASO ;
DR   B2S4U1, RSMA_BRUA1 ;  Q2YN15, RSMA_BRUA2 ;  Q57E58, RSMA_BRUAB ;
DR   A9MA55, RSMA_BRUC2 ;  C0RI23, RSMA_BRUMB ;  Q8YG94, RSMA_BRUME ;
DR   A5VPL7, RSMA_BRUO2 ;  B0CL06, RSMA_BRUSI ;  Q8G1N0, RSMA_BRUSU ;
DR   P57241, RSMA_BUCAI ;  Q8KA00, RSMA_BUCAP ;  P59524, RSMA_BUCBP ;
DR   B1YWD5, RSMA_BURA4 ;  Q1BTQ8, RSMA_BURCA ;  B1JY71, RSMA_BURCC ;
DR   A0KAD1, RSMA_BURCH ;  B4EBE8, RSMA_BURCJ ;  Q0BC07, RSMA_BURCM ;
DR   A9AFE4, RSMA_BURM1 ;  A3MNW4, RSMA_BURM7 ;  A2S8N7, RSMA_BURM9 ;
DR   Q62MM2, RSMA_BURMA ;  A1V727, RSMA_BURMS ;  A3NRM0, RSMA_BURP0 ;
DR   Q3JVW6, RSMA_BURP1 ;  A3N5X6, RSMA_BURP6 ;  B2JCX3, RSMA_BURP8 ;
DR   B2SX63, RSMA_BURPP ;  Q63X76, RSMA_BURPS ;  Q39D37, RSMA_BURS3 ;
DR   Q9RED9, RSMA_BURSP ;  Q2T114, RSMA_BURTA ;  A4JHP7, RSMA_BURVG ;
DR   Q145L1, RSMA_BURXL ;  A7ZGB4, RSMA_CAMC1 ;  A7GVW6, RSMA_CAMC5 ;
DR   A0RRT6, RSMA_CAMFF ;  A7I417, RSMA_CAMHC ;  Q9PLW7, RSMA_CAMJE ;
DR   Q5HS85, RSMA_CAMJR ;  Q3A8X5, RSMA_CARHZ ;  Q9A7N5, RSMA_CAUCR ;
DR   Q5L6H5, RSMA_CHLAB ;  Q3ARC0, RSMA_CHLCH ;  Q823V2, RSMA_CHLCV ;
DR   Q253R6, RSMA_CHLFF ;  B3EIC2, RSMA_CHLL2 ;  Q9PK40, RSMA_CHLMU ;
DR   B3QMU5, RSMA_CHLP8 ;  B3EQT0, RSMA_CHLPB ;  A1BFM9, RSMA_CHLPD ;
DR   Q9Z6K0, RSMA_CHLPN ;  B0B7S3, RSMA_CHLT2 ;  Q3KM04, RSMA_CHLTA ;
DR   B0BBY8, RSMA_CHLTB ;  Q8KE87, RSMA_CHLTE ;  O84358, RSMA_CHLTR ;
DR   Q1QZ31, RSMA_CHRSD ;  Q7P1U1, RSMA_CHRVO ;  A8ALP9, RSMA_CITK8 ;
DR   Q97EX0, RSMA_CLOAB ;  A7FQA9, RSMA_CLOB1 ;  C3KXY4, RSMA_CLOB6 ;
DR   C1FQ40, RSMA_CLOBJ ;  B1ID54, RSMA_CLOBK ;  A7G9I5, RSMA_CLOBL ;
DR   B1KRY8, RSMA_CLOBM ;  Q181C1, RSMA_CLOD6 ;  Q0TMD6, RSMA_CLOP1 ;
DR   Q8XHG8, RSMA_CLOPE ;  A9KL97, RSMA_CLOPH ;  Q0SQ34, RSMA_CLOPS ;
DR   Q47VJ8, RSMA_COLP3 ;  Q6NIA2, RSMA_CORDI ;  Q8FQZ5, RSMA_COREF ;
DR   A4QCP0, RSMA_CORGB ;  Q8NRY1, RSMA_CORGL ;  Q4JU23, RSMA_CORJK ;
DR   B6J641, RSMA_COXB1 ;  B6J3A6, RSMA_COXB2 ;  A9KGZ8, RSMA_COXBN ;
DR   A9N9I7, RSMA_COXBR ;  Q83AC2, RSMA_COXBU ;  Q0KEA7, RSMA_CUPNH ;
DR   Q475Q1, RSMA_CUPPJ ;  B2AH89, RSMA_CUPTR ;  B1WRJ7, RSMA_CYAA5 ;
DR   B7JWJ7, RSMA_CYAP8 ;  Q11UL8, RSMA_CYTH3 ;  Q479U6, RSMA_DECAR ;
DR   Q3Z9F0, RSMA_DEHE1 ;  A5FS52, RSMA_DEHSB ;  Q3ZZE6, RSMA_DEHSC ;
DR   Q1IZ94, RSMA_DEIGD ;  Q9RU68, RSMA_DEIRA ;  C6BSW3, RSMA_DESAD ;
DR   C0QFJ2, RSMA_DESAH ;  Q30ZP0, RSMA_DESDG ;  B8FY38, RSMA_DESHD ;
DR   Q251W8, RSMA_DESHY ;  A9A0E0, RSMA_DESOH ;  Q6AL71, RSMA_DESPS ;
DR   Q72B41, RSMA_DESVH ;  A1VD65, RSMA_DESVV ;  A5EY68, RSMA_DICNV ;
DR   A8LI73, RSMA_DINSH ;  A7ZHE4, RSMA_ECO24 ;  B7UI99, RSMA_ECO27 ;
DR   B7MAH6, RSMA_ECO45 ;  B7L4H4, RSMA_ECO55 ;  Q8XA14, RSMA_ECO57 ;
DR   B5YZ89, RSMA_ECO5E ;  B7NHF7, RSMA_ECO7I ;  B7MNR0, RSMA_ECO81 ;
DR   B7M0E8, RSMA_ECO8A ;  C4ZPX7, RSMA_ECOBW ;  B1XC52, RSMA_ECODH ;
DR   A7ZW03, RSMA_ECOHS ;  A1A7A0, RSMA_ECOK1 ;  Q0TLT6, RSMA_ECOL5 ;
DR   Q8FL96, RSMA_ECOL6 ;  B1IRC5, RSMA_ECOLC ;  P06992, RSMA_ECOLI ;
DR   B7N7S6, RSMA_ECOLU ;  B6HZ32, RSMA_ECOSE ;  B1LFY7, RSMA_ECOSM ;
DR   Q1RGE6, RSMA_ECOUT ;  Q3YS70, RSMA_EHRCJ ;  Q2GGH6, RSMA_EHRCR ;
DR   Q5FH30, RSMA_EHRRG ;  Q5HBC6, RSMA_EHRRW ;  A4W6F7, RSMA_ENT38 ;
DR   Q837A7, RSMA_ENTFA ;  A7MIA7, RSMA_ENTS8 ;  Q6D0E0, RSMA_ERWCT ;
DR   B2VGP6, RSMA_ERWT9 ;  Q2N8W9, RSMA_ERYLH ;  B7LVU5, RSMA_ESCF3 ;
DR   A5FLP4, RSMA_FLAJ1 ;  A6GVR5, RSMA_FLAPJ ;  B0TZ54, RSMA_FRAP2 ;
DR   Q14IY7, RSMA_FRAT1 ;  A7NDV3, RSMA_FRATF ;  Q2A218, RSMA_FRATH ;
DR   B2SDQ1, RSMA_FRATM ;  A0Q5E0, RSMA_FRATN ;  Q0BKP7, RSMA_FRATO ;
DR   Q5NHI5, RSMA_FRATT ;  A4IZF1, RSMA_FRATW ;  Q8R6B1, RSMA_FUSNN ;
DR   Q5L3V8, RSMA_GEOKA ;  Q39W34, RSMA_GEOMG ;  Q74C12, RSMA_GEOSL ;
DR   C5D363, RSMA_GEOSW ;  A4IJB8, RSMA_GEOTN ;  Q7NJ41, RSMA_GLOVI ;
DR   Q5FU61, RSMA_GLUOX ;  Q7VM33, RSMA_HAEDU ;  Q4QMZ9, RSMA_HAEI8 ;
DR   A5U9U3, RSMA_HAEIE ;  A5UH57, RSMA_HAEIG ;  P44749, RSMA_HAEIN ;
DR   Q0I5C3, RSMA_HAES1 ;  B0URM7, RSMA_HAES2 ;  Q2S9C3, RSMA_HAHCH ;
DR   A1WVT7, RSMA_HALHL ;  B8D0I2, RSMA_HALOH ;  C4K4K9, RSMA_HAMD5 ;
DR   Q17ZF9, RSMA_HELAH ;  Q7VGZ3, RSMA_HELHP ;  B6JNS3, RSMA_HELP2 ;
DR   B5Z950, RSMA_HELPG ;  Q1CRJ9, RSMA_HELPH ;  Q9ZJI7, RSMA_HELPJ ;
DR   B2UVG9, RSMA_HELPS ;  O25972, RSMA_HELPY ;  A4G256, RSMA_HERAR ;
DR   B4U9C8, RSMA_HYDS0 ;  Q5QVN7, RSMA_IDILO ;  A6SV13, RSMA_JANMA ;
DR   Q28RD6, RSMA_JANSC ;  A6W6U4, RSMA_KINRD ;  B5Y1Z4, RSMA_KLEP3 ;
DR   A6T4I7, RSMA_KLEP7 ;  Q5FMG3, RSMA_LACAC ;  Q03T56, RSMA_LACBA ;
DR   Q1GBR1, RSMA_LACDA ;  Q04C60, RSMA_LACDB ;  A8YX55, RSMA_LACH4 ;
DR   Q74LI0, RSMA_LACJO ;  Q9CHN8, RSMA_LACLA ;  Q88Z93, RSMA_LACPL ;
DR   A5VI09, RSMA_LACRD ;  B2G5I8, RSMA_LACRJ ;  Q1WV73, RSMA_LACS1 ;
DR   Q38V22, RSMA_LACSS ;  C1D9C2, RSMA_LARHH ;  Q1MR01, RSMA_LAWIP ;
DR   Q5X0V1, RSMA_LEGPA ;  A5IIC0, RSMA_LEGPC ;  Q5ZRF4, RSMA_LEGPH ;
DR   Q5WSM3, RSMA_LEGPL ;  Q6ADP1, RSMA_LEIXX ;  B1Y7L9, RSMA_LEPCP ;
DR   B1N079, RSMA_LEUCK ;  Q03VR7, RSMA_LEUMM ;  Q92F79, RSMA_LISIN ;
DR   C1KYC1, RSMA_LISMC ;  Q724M5, RSMA_LISMF ;  B8DGN7, RSMA_LISMH ;
DR   Q8YAE2, RSMA_LISMO ;  A0AEZ3, RSMA_LISW6 ;  B1HS82, RSMA_LYSSC ;
DR   B9E8V8, RSMA_MACCJ ;  Q2W0V3, RSMA_MAGSA ;  A0LA32, RSMA_MAGSM ;
DR   Q65UX3, RSMA_MANSM ;  A1U6F8, RSMA_MARAV ;  Q0AQC3, RSMA_MARMM ;
DR   A6VU53, RSMA_MARMS ;  Q6F2B4, RSMA_MESFL ;  Q11HG9, RSMA_MESSB ;
DR   Q60B77, RSMA_METCA ;  Q1GZB8, RSMA_METFK ;  A2SC77, RSMA_METPP ;
DR   B1LVB8, RSMA_METRJ ;  Q2RME8, RSMA_MOOTA ;  A0QBW0, RSMA_MYCA1 ;
DR   B3PLS2, RSMA_MYCA5 ;  P66661, RSMA_MYCBO ;  A1KHE8, RSMA_MYCBP ;
DR   C1AM01, RSMA_MYCBT ;  P43038, RSMA_MYCCT ;  Q7NC69, RSMA_MYCGA ;
DR   P47701, RSMA_MYCGE ;  A4T6P3, RSMA_MYCGI ;  Q5ZZN4, RSMA_MYCH2 ;
DR   Q4A775, RSMA_MYCH7 ;  Q4A936, RSMA_MYCHJ ;  B8ZU59, RSMA_MYCLB ;
DR   Q9CD52, RSMA_MYCLE ;  Q6KH80, RSMA_MYCMO ;  Q6MUM4, RSMA_MYCMS ;
DR   Q741W2, RSMA_MYCPA ;  Q8EU92, RSMA_MYCPE ;  P75113, RSMA_MYCPN ;
DR   Q98RJ3, RSMA_MYCPU ;  Q4A645, RSMA_MYCS5 ;  A3Q5I0, RSMA_MYCSJ ;
DR   A1UL32, RSMA_MYCSK ;  Q1B416, RSMA_MYCSS ;  A5U153, RSMA_MYCTA ;
DR   P66660, RSMA_MYCTU ;  A1TEH3, RSMA_MYCVP ;  Q1DAP2, RSMA_MYXXD ;
DR   B2A3L9, RSMA_NATTJ ;  Q5F9W4, RSMA_NEIG1 ;  B4RJV5, RSMA_NEIG2 ;
DR   A9M352, RSMA_NEIM0 ;  Q9JVC2, RSMA_NEIMA ;  Q9K0B7, RSMA_NEIMB ;
DR   A1KSW0, RSMA_NEIMF ;  Q2GE45, RSMA_NEOSM ;  Q0AGQ8, RSMA_NITEC ;
DR   Q82W15, RSMA_NITEU ;  Q1QKW0, RSMA_NITHX ;  Q2YBP5, RSMA_NITMU ;
DR   Q3JAF3, RSMA_NITOC ;  Q3SRZ8, RSMA_NITWN ;  Q5YPY6, RSMA_NOCFA ;
DR   B2J0A6, RSMA_NOSP7 ;  Q8YS62, RSMA_NOSS1 ;  Q2G9Z2, RSMA_NOVAD ;
DR   P59155, RSMA_OCEIH ;  A6X265, RSMA_OCHA4 ;  Q04DR8, RSMA_OENOB ;
DR   B6JGM4, RSMA_OLICO ;  Q6YPJ4, RSMA_ONYPE ;  B1ZW80, RSMA_OPITP ;
DR   A6LF39, RSMA_PARD8 ;  A1B0G4, RSMA_PARDP ;  Q6ME80, RSMA_PARUW ;
DR   Q9CLL5, RSMA_PASMU ;  C6DEY6, RSMA_PECCP ;  Q03HF6, RSMA_PEDPA ;
DR   Q3A3G8, RSMA_PELCD ;  Q3B3D4, RSMA_PELLD ;  A5D673, RSMA_PELTS ;
DR   Q4FMR0, RSMA_PELUB ;  C0QUE5, RSMA_PERMH ;  B4RBS4, RSMA_PHEZH ;
DR   Q7N8V7, RSMA_PHOLL ;  Q6LV41, RSMA_PHOPR ;  B1V9I5, RSMA_PHYAS ;
DR   A1VUN7, RSMA_POLNA ;  Q121Q5, RSMA_POLSJ ;  B2RHC2, RSMA_PORG3 ;
DR   Q7MXN7, RSMA_PORGI ;  B4S787, RSMA_PROA2 ;  Q6AAD7, RSMA_PROAC ;
DR   A3PCS3, RSMA_PROM0 ;  A2C1Z5, RSMA_PROM1 ;  A8G4P1, RSMA_PROM2 ;
DR   A2CA51, RSMA_PROM3 ;  A9B9Y0, RSMA_PROM4 ;  A2BWR2, RSMA_PROM5 ;
DR   Q31B19, RSMA_PROM9 ;  Q7VCH7, RSMA_PROMA ;  B4F2I2, RSMA_PROMH ;
DR   Q7V7W0, RSMA_PROMM ;  Q7V1E1, RSMA_PROMP ;  A2BR00, RSMA_PROMS ;
DR   Q46L58, RSMA_PROMT ;  Q48NT7, RSMA_PSE14 ;  Q9I5U5, RSMA_PSEAE ;
DR   Q4K4X5, RSMA_PSEF5 ;  Q3IFD1, RSMA_PSEHT ;  Q3K5T2, RSMA_PSEPF ;
DR   Q88QT6, RSMA_PSEPK ;  Q88A46, RSMA_PSESM ;  Q4ZMG5, RSMA_PSEU2 ;
DR   Q4FT44, RSMA_PSYA2 ;  Q1QAR8, RSMA_PSYCK ;  A1STS1, RSMA_PSYIN ;
DR   Q1LRA1, RSMA_RALME ;  Q8Y219, RSMA_RALSO ;  B3PUU6, RSMA_RHIE6 ;
DR   Q2KA84, RSMA_RHIEC ;  Q1MJ01, RSMA_RHIL3 ;  Q984S7, RSMA_RHILO ;
DR   B5ZWD8, RSMA_RHILW ;  Q92QZ1, RSMA_RHIME ;  C3M9C2, RSMA_RHISN ;
DR   Q7UIR4, RSMA_RHOBA ;  C1A383, RSMA_RHOE4 ;  Q223E6, RSMA_RHOFD ;
DR   C1AXY5, RSMA_RHOOB ;  Q2IX80, RSMA_RHOP2 ;  Q07LF4, RSMA_RHOP5 ;
DR   Q6N5B4, RSMA_RHOPA ;  Q215S4, RSMA_RHOPB ;  Q135P2, RSMA_RHOPS ;
DR   B3Q9S4, RSMA_RHOPT ;  Q2RXA9, RSMA_RHORT ;  A3PJZ3, RSMA_RHOS1 ;
DR   Q3J2B9, RSMA_RHOS4 ;  A4WRK3, RSMA_RHOS5 ;  B9KST5, RSMA_RHOSK ;
DR   Q0S4T6, RSMA_RHOSR ;  C3PPC3, RSMA_RICAE ;  A8GPG7, RSMA_RICAH ;
DR   A8GXS7, RSMA_RICB8 ;  Q1RK29, RSMA_RICBR ;  A8EZN3, RSMA_RICCK ;
DR   Q92GV0, RSMA_RICCN ;  Q4UMV1, RSMA_RICFE ;  O05952, RSMA_RICPR ;
DR   C4K2J5, RSMA_RICPU ;  A8GT85, RSMA_RICRS ;  Q68W66, RSMA_RICTY ;
DR   Q164G1, RSMA_ROSDO ;  Q1AXL9, RSMA_RUBXD ;  Q21MT0, RSMA_SACD2 ;
DR   B5F771, RSMA_SALA4 ;  A9MQG2, RSMA_SALAR ;  Q57TH0, RSMA_SALCH ;
DR   B5FI34, RSMA_SALDC ;  B5R1S8, RSMA_SALEP ;  B5RGC2, RSMA_SALG2 ;
DR   B4TJ47, RSMA_SALHS ;  B4T6L6, RSMA_SALNS ;  Q5PDD9, RSMA_SALPA ;
DR   A9MYM4, RSMA_SALPB ;  C0Q5E7, RSMA_SALPC ;  B5BL27, RSMA_SALPK ;
DR   Q2S0I2, RSMA_SALRD ;  B4TWT6, RSMA_SALSV ;  Q8Z9J7, RSMA_SALTI ;
DR   Q56016, RSMA_SALTY ;  A8G9P0, RSMA_SERP5 ;  A1S9G5, RSMA_SHEAM ;
DR   B8EB35, RSMA_SHEB2 ;  A3D188, RSMA_SHEB5 ;  A6WK59, RSMA_SHEB8 ;
DR   A9L438, RSMA_SHEB9 ;  Q12K59, RSMA_SHEDO ;  Q07YJ8, RSMA_SHEFN ;
DR   B0TV52, RSMA_SHEHH ;  A3QBA3, RSMA_SHELP ;  Q8EB93, RSMA_SHEON ;
DR   A8H0V2, RSMA_SHEPA ;  A4Y435, RSMA_SHEPC ;  B8CSX5, RSMA_SHEPW ;
DR   A0L064, RSMA_SHESA ;  A8FRV2, RSMA_SHESH ;  Q0HLT2, RSMA_SHESM ;
DR   Q0HS06, RSMA_SHESR ;  A1RMU8, RSMA_SHESW ;  B1KGH9, RSMA_SHEWM ;
DR   B2U259, RSMA_SHIB3 ;  Q326I2, RSMA_SHIBS ;  Q32K43, RSMA_SHIDS ;
DR   Q0T8E4, RSMA_SHIF8 ;  Q83MG8, RSMA_SHIFL ;  Q3Z5V8, RSMA_SHISS ;
DR   Q5LQN0, RSMA_SILPO ;  Q1GI39, RSMA_SILST ;  A6U7I6, RSMA_SINMW ;
DR   Q2NVX6, RSMA_SODGM ;  Q1GT31, RSMA_SPHAL ;  A7WYP0, RSMA_STAA1 ;
DR   A6TYW7, RSMA_STAA2 ;  Q2FJE9, RSMA_STAA3 ;  Q2G0T0, RSMA_STAA8 ;
DR   A5IQ45, RSMA_STAA9 ;  Q2YVV2, RSMA_STAAB ;  Q5HII3, RSMA_STAAC ;
DR   A6QEE6, RSMA_STAAE ;  Q932G1, RSMA_STAAM ;  P66662, RSMA_STAAN ;
DR   Q6GJH8, RSMA_STAAR ;  Q6GBZ5, RSMA_STAAS ;  A8Z0Y8, RSMA_STAAT ;
DR   P66663, RSMA_STAAW ;  B9DLD0, RSMA_STACT ;  Q5HRR2, RSMA_STAEQ ;
DR   Q8CQU5, RSMA_STAES ;  Q4L3F0, RSMA_STAHJ ;  Q49V02, RSMA_STAS1 ;
DR   Q3JZA5, RSMA_STRA1 ;  Q8E3D7, RSMA_STRA3 ;  Q8DXR8, RSMA_STRA5 ;
DR   Q82HC3, RSMA_STRAW ;  Q9K3R5, RSMA_STRCO ;  C0M8P2, RSMA_STRE4 ;
DR   B4U0U9, RSMA_STREM ;  A8AUQ4, RSMA_STRGC ;  B1VUF9, RSMA_STRGG ;
DR   P59156, RSMA_STRMU ;  Q9A1I0, RSMA_STRP1 ;  Q04II4, RSMA_STRP2 ;
DR   P0DF12, RSMA_STRP3 ;  B5E2H6, RSMA_STRP4 ;  Q5XDX4, RSMA_STRP6 ;
DR   C1CA29, RSMA_STRP7 ;  Q8P2N8, RSMA_STRP8 ;  Q1JDL6, RSMA_STRPB ;
DR   Q1JNI8, RSMA_STRPC ;  Q1JIN6, RSMA_STRPD ;  Q1J8J4, RSMA_STRPF ;
DR   A2RCH2, RSMA_STRPG ;  B1I8T7, RSMA_STRPI ;  B8ZNY9, RSMA_STRPJ ;
DR   Q48VC6, RSMA_STRPM ;  Q97NN5, RSMA_STRPN ;  P0DF13, RSMA_STRPQ ;
DR   B2IM67, RSMA_STRPS ;  Q8DND3, RSMA_STRR6 ;  C0MF36, RSMA_STRS7 ;
DR   A3CQN5, RSMA_STRSV ;  Q5LY12, RSMA_STRT1 ;  Q5M2L6, RSMA_STRT2 ;
DR   Q03IR2, RSMA_STRTD ;  B9DVT4, RSMA_STRU0 ;  C1CGR5, RSMA_STRZJ ;
DR   C1CMT3, RSMA_STRZP ;  C1CTN9, RSMA_STRZT ;  Q30NR7, RSMA_SULDN ;
DR   B2V963, RSMA_SULSY ;  Q67JB9, RSMA_SYMTH ;  Q2LSQ6, RSMA_SYNAS ;
DR   Q31RH6, RSMA_SYNE7 ;  Q2JVW2, RSMA_SYNJA ;  Q2JMR8, RSMA_SYNJB ;
DR   B1XIV9, RSMA_SYNP2 ;  Q5N2S8, RSMA_SYNP6 ;  A5GLH7, RSMA_SYNPW ;
DR   Q7U7D3, RSMA_SYNPX ;  A5GTK9, RSMA_SYNR3 ;  Q0I9S3, RSMA_SYNS3 ;
DR   Q3AXF3, RSMA_SYNS9 ;  Q3AKE0, RSMA_SYNSC ;  P72666, RSMA_SYNY3 ;
DR   P59157, RSMA_THEEB ;  Q47SX4, RSMA_THEFY ;  Q9X1F1, RSMA_THEMA ;
DR   B9K8F0, RSMA_THENN ;  A5IME8, RSMA_THEP1 ;  B1LBH5, RSMA_THESQ ;
DR   Q72GC7, RSMA_THET2 ;  Q5SM60, RSMA_THET8 ;  Q8RDC8, RSMA_THETN ;
DR   Q31F24, RSMA_THICR ;  Q3SGF7, RSMA_THIDA ;  C4L9L4, RSMA_TOLAT ;
DR   Q73NS2, RSMA_TREDE ;  O83357, RSMA_TREPA ;  B2S2T4, RSMA_TREPS ;
DR   B1AJP2, RSMA_UREP2 ;  Q9PPN8, RSMA_UREPA ;  B5ZCB6, RSMA_UREU1 ;
DR   C5CS95, RSMA_VARPS ;  A1WS95, RSMA_VEREI ;  A5F8N2, RSMA_VIBC3 ;
DR   Q9KUS2, RSMA_VIBCH ;  Q5E865, RSMA_VIBF1 ;  B5FGG5, RSMA_VIBFM ;
DR   A7MWC6, RSMA_VIBHB ;  Q87ST6, RSMA_VIBPA ;  B7VIE2, RSMA_VIBSL ;
DR   Q8DED2, RSMA_VIBVU ;  Q7MP86, RSMA_VIBVY ;  Q8D3I1, RSMA_WIGBR ;
DR   Q73IR3, RSMA_WOLPM ;  B3CPY6, RSMA_WOLPP ;  Q5GSM9, RSMA_WOLTR ;
DR   C0R5G4, RSMA_WOLWR ;  Q8PP25, RSMA_XANAC ;  Q3BX82, RSMA_XANC5 ;
DR   Q4UR39, RSMA_XANC8 ;  B0RUI3, RSMA_XANCB ;  Q8PCE3, RSMA_XANCP ;
DR   Q2NZI4, RSMA_XANOM ;  B2SPT3, RSMA_XANOP ;  Q5GWB9, RSMA_XANOR ;
DR   A7IJ80, RSMA_XANP2 ;  Q9PBJ6, RSMA_XYLFA ;  Q87C85, RSMA_XYLFT ;
DR   A1JJF4, RSMA_YERE8 ;  A7FMC1, RSMA_YERP3 ;  Q1C0H5, RSMA_YERPA ;
DR   B2K487, RSMA_YERPB ;  Q8ZIK5, RSMA_YERPE ;  A9QZZ0, RSMA_YERPG ;
DR   Q1CMT2, RSMA_YERPN ;  A4TQD8, RSMA_YERPP ;  Q66EQ8, RSMA_YERPS ;
DR   B1JKY3, RSMA_YERPY ;  Q5NMX2, RSMA_ZYMMO ;
//
ID   2.1.1.183
DE   18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase.
CA   4 S-adenosyl-L-methionine + adenine(1779)/adenine(1780) in 18S rRNA =
CA   4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1779)/N(6)-
CA   dimethyladenine(1780) in 18S rRNA.
CC   -!- DIM1 is involved in pre-rRNA processing.
CC   -!- Formerly EC 2.1.1.48.
DR   Q75C90, DIM1_ASHGO ;  Q6FKY3, DIM1_CANGA ;  Q6BSY5, DIM1_DEBHA ;
DR   P78697, DIM1_KLULA ;  Q9USU2, DIM1_SCHPO ;  Q6C7H6, DIM1_YARLI ;
DR   P41819, DIM1_YEAST ;  Q2KHT8, DIMT1_BOVIN;  Q09522, DIMT1_CAEEL;
DR   Q54QK7, DIMT1_DICDI;  Q9VAQ5, DIMT1_DROME;  Q9UNQ2, DIMT1_HUMAN;
DR   Q95KJ0, DIMT1_MACFA;  Q9D0D4, DIMT1_MOUSE;
//
ID   2.1.1.184
DE   23S rRNA (adenine(2085)-N(6))-dimethyltransferase.
CA   2 S-adenosyl-L-methionine + adenine(2085) in 23S rRNA = 2 S-adenosyl-L-
CA   homocysteine + N(6)-dimethyladenine(2085) in 23S rRNA.
CC   -!- ErmC is a methyltransferase that confers resistance to the macrolide-
CC       lincosamide-streptogramin B group of antibiotics by catalyzing the
CC       methylation of 23S rRNA at adenine(2085).
CC   -!- Formerly EC 2.1.1.48.
DR   P0A4D6, ERM1_CLOPE ;  P0A4D5, ERM1_ENTFA ;  P0A0H1, ERMA_STAAM ;
DR   P0A0H2, ERMA_STAAN ;  Q6GKQ0, ERMA_STAAR ;  P0A0H3, ERMA_STAAU ;
DR   P10738, ERMB_ECOLX ;  P20173, ERMB_ENTFA ;  P02979, ERMC1_STAAU;
DR   P13957, ERMC2_STAAU;  P13978, ERMC3_STAAU;  P07287, ERME_SACEN ;
DR   Q00014, ERMG_LACRE ;  P06572, ERMM_STAEP ;  P45439, ERMS_STRFR ;
DR   P13956, ERM_BACSU  ;  P21236, ERM_STRPN  ;  P06573, ERM_STRSA  ;
//
ID   2.1.1.185
DE   23S rRNA (guanine(2251)-2'-O)-methyltransferase.
CA   S-adenosyl-L-methionine + guanosine(2251) in 23S rRNA = S-adenosyl-L-
CA   homocysteine + 2'-O-methylguanosine(2251) in 23S rRNA.
CC   -!- The enzyme catalyzes the methylation of guanosine(2251),
CC       a modification conserved in the peptidyltransferase domain of 23S
CC       rRNA.
//
ID   2.1.1.186
DE   23S rRNA (cytidine(2498)-2'-O)-methyltransferase.
CA   S-adenosyl-L-methionine + cytidine(2498) in 23S rRNA = S-adenosyl-L-
CA   homocysteine + 2'-O-methylcytidine(2498) in 23S rRNA.
//
ID   2.1.1.187
DE   23S rRNA (guanine(745)-N(1))-methyltransferase.
AN   23S rRNA m(1)G(745) methyltransferase.
AN   Ribosomal RNA(m(1)G)-methylase.
CA   S-adenosyl-L-methionine + guanine(745) in 23S rRNA = S-adenosyl-L-
CA   homocysteine + N(1)-methylguanine(745) in 23S rRNA.
CC   -!- The enzyme specifically methylates guanine(745) at N(1) in 23S rRNA.
CC   -!- Formerly EC 2.1.1.51.
DR   P36999, RLMA_ECOLI ;
//
ID   2.1.1.188
DE   23S rRNA (guanine(748)-N(1))-methyltransferase.
AN   23S rRNA m(1)G(748) methyltransferase.
AN   rRNA large subunit methyltransferase II.
AN   Tylosin-resistance methyltransferase RlmA(II).
CA   S-adenosyl-L-methionine + guanine(748) in 23S rRNA = S-adenosyl-L-
CA   homocysteine + N(1)-methylguanine(748) in 23S rRNA.
CC   -!- The enzyme specifically methylates guanine(748) at N(1) in 23S rRNA.
CC   -!- The methyltransferase RlmA(II) confers resistance to the macrolide
CC       antibiotic tylosin in the drug-producing strain Streptomyces fradiae.
CC   -!- Formerly EC 2.1.1.51.
//
ID   2.1.1.189
DE   23S rRNA (uracil(747)-C(5))-methyltransferase.
CA   S-adenosyl-L-methionine + uracil(747) in 23S rRNA = S-adenosyl-L-
CA   homocysteine + 5-methyluracil(747) in 23S rRNA.
CC   -!- The enzyme specifically methylates uracil(747) at C(5) in 23S rRNA.
DR   A8AIQ7, RUMB_CITK8 ;  A7ZJS7, RUMB_ECO24 ;  B7UMV1, RUMB_ECO27 ;
DR   B7MHG3, RUMB_ECO45 ;  B7LD52, RUMB_ECO55 ;  Q8X6Q5, RUMB_ECO57 ;
DR   B5YSF1, RUMB_ECO5E ;  B7NPF5, RUMB_ECO7I ;  B7MQW3, RUMB_ECO81 ;
DR   B7M7D4, RUMB_ECO8A ;  C4ZY31, RUMB_ECOBW ;  B1X800, RUMB_ECODH ;
DR   A7ZYG2, RUMB_ECOHS ;  A1A998, RUMB_ECOK1 ;  Q0TJI9, RUMB_ECOL5 ;
DR   Q8FJE7, RUMB_ECOL6 ;  B1IWR3, RUMB_ECOLC ;  P75817, RUMB_ECOLI ;
DR   B7NAK5, RUMB_ECOLU ;  B6I8H9, RUMB_ECOSE ;  B1LN12, RUMB_ECOSM ;
DR   Q1RE66, RUMB_ECOUT ;  A4W8M4, RUMB_ENT38 ;  A7MF48, RUMB_ENTS8 ;
DR   Q6D3S2, RUMB_ERWCT ;  B7LN23, RUMB_ESCF3 ;  Q7VNM5, RUMB_HAEDU ;
DR   Q4QLU9, RUMB_HAEI8 ;  A5UDB0, RUMB_HAEIE ;  A5UI99, RUMB_HAEIG ;
DR   P44083, RUMB_HAEIN ;  Q65VK8, RUMB_MANSM ;  Q9CPH1, RUMB_PASMU ;
DR   C6DEQ3, RUMB_PECCP ;  Q7N6G6, RUMB_PHOLL ;  B5F101, RUMB_SALA4 ;
DR   A9MIM3, RUMB_SALAR ;  Q57R80, RUMB_SALCH ;  B5FPZ6, RUMB_SALDC ;
DR   B5QYK4, RUMB_SALEP ;  B4T0E3, RUMB_SALNS ;  Q5PGN2, RUMB_SALPA ;
DR   A9N824, RUMB_SALPB ;  C0PXN9, RUMB_SALPC ;  B5BBV5, RUMB_SALPK ;
DR   Q8Z841, RUMB_SALTI ;  Q8ZQJ5, RUMB_SALTY ;  A8GCB4, RUMB_SERP5 ;
DR   A1S382, RUMB_SHEAM ;  B8E5Q5, RUMB_SHEB2 ;  A3D0Y0, RUMB_SHEB5 ;
DR   A6WS34, RUMB_SHEB8 ;  A9L1I5, RUMB_SHEB9 ;  Q087X5, RUMB_SHEFN ;
DR   A3QB25, RUMB_SHELP ;  Q8EI67, RUMB_SHEON ;  A4Y9Y4, RUMB_SHEPC ;
DR   A0L0G4, RUMB_SHESA ;  Q0HM20, RUMB_SHESM ;  Q0HRR5, RUMB_SHESR ;
DR   A1RGE6, RUMB_SHESW ;  B2TUM0, RUMB_SHIB3 ;  Q323P2, RUMB_SHIBS ;
DR   Q32ID7, RUMB_SHIDS ;  Q0T8K2, RUMB_SHIF8 ;  Q83S14, RUMB_SHIFL ;
DR   Q3Z3S5, RUMB_SHISS ;  A5F0U5, RUMB_VIBC3 ;  Q9KL20, RUMB_VIBCH ;
DR   C3LWJ3, RUMB_VIBCM ;  Q8D4B4, RUMB_VIBVU ;  Q7MFU0, RUMB_VIBVY ;
DR   A1JM74, RUMB_YERE8 ;  A7FK27, RUMB_YERP3 ;  Q1CAC8, RUMB_YERPA ;
DR   B2K9X0, RUMB_YERPB ;  Q8ZGG1, RUMB_YERPE ;  A9R4V6, RUMB_YERPG ;
DR   Q1CGA8, RUMB_YERPN ;  A4TN73, RUMB_YERPP ;  Q66CN7, RUMB_YERPS ;
DR   B1JRJ4, RUMB_YERPY ;
//
ID   2.1.1.190
DE   23S rRNA (uracil(1939)-C(5))-methyltransferase.
AN   RNA uridine methyltransferase A.
CA   S-adenosyl-L-methionine + uracil(1939) in 23S rRNA = S-adenosyl-L-
CA   homocysteine + 5-methyluracil(1939) in 23S rRNA.
CC   -!- The enzyme specifically methylates uracil(1939) at C(5) in 23S rRNA.
CC   -!- The enzyme contains an [4Fe-4S] cluster coordinated by four conserved
CC       cysteine residues.
DR   A1TSE0, RUMA_ACIAC ;  Q6F847, RUMA_ACIAD ;  B7H018, RUMA_ACIB3 ;
DR   B7I675, RUMA_ACIB5 ;  B2HTF7, RUMA_ACIBC ;  B0VKL3, RUMA_ACIBS ;
DR   B0V5N2, RUMA_ACIBY ;  B7J921, RUMA_ACIF2 ;  B5EPA4, RUMA_ACIF5 ;
DR   A1W8J9, RUMA_ACISJ ;  A0KGG9, RUMA_AERHH ;  A4SRC5, RUMA_AERS4 ;
DR   Q0VP26, RUMA_ALCBS ;  Q0A8Y4, RUMA_ALHEH ;  B6EKM3, RUMA_ALISL ;
DR   Q5P841, RUMA_AROAE ;  A1K4G2, RUMA_AZOSB ;  Q2L016, RUMA_BORA1 ;
DR   Q7WI42, RUMA_BORBR ;  Q7W676, RUMA_BORPA ;  Q7VXM6, RUMA_BORPE ;
DR   Q1BGX9, RUMA_BURCA ;  A0K7U1, RUMA_BURCH ;  Q0BEW2, RUMA_BURCM ;
DR   Q62JV9, RUMA_BURMA ;  Q3JRP8, RUMA_BURP1 ;  Q63UT8, RUMA_BURPS ;
DR   Q39FQ4, RUMA_BURS3 ;  Q2SWE9, RUMA_BURTA ;  Q13Z67, RUMA_BURXL ;
DR   Q7NWP9, RUMA_CHRVO ;  A8ANZ1, RUMA_CITK8 ;  Q47WQ1, RUMA_COLP3 ;
DR   Q0K956, RUMA_CUPNH ;  Q46ZH7, RUMA_CUPPJ ;  Q47HS4, RUMA_DECAR ;
DR   Q8XED8, RUMA_ECO57 ;  A1AEX2, RUMA_ECOK1 ;  Q0TE74, RUMA_ECOL5 ;
DR   Q8FEG6, RUMA_ECOL6 ;  P55135, RUMA_ECOLI ;  Q1R7Q7, RUMA_ECOUT ;
DR   C5B8X6, RUMA_EDWI9 ;  A4WDX1, RUMA_ENT38 ;  A7MQZ8, RUMA_ENTS8 ;
DR   Q6D178, RUMA_ERWCT ;  B2VFZ2, RUMA_ERWT9 ;  Q14IC3, RUMA_FRAT1 ;
DR   Q2A275, RUMA_FRATH ;  A0Q5J5, RUMA_FRATN ;  Q0BKU7, RUMA_FRATO ;
DR   Q5NGX1, RUMA_FRATT ;  Q7VKU9, RUMA_HAEDU ;  Q4QNK7, RUMA_HAEI8 ;
DR   P44643, RUMA_HAEIN ;  Q0I127, RUMA_HAES1 ;  Q2SL27, RUMA_HAHCH ;
DR   B5XV15, RUMA_KLEP3 ;  A6TD57, RUMA_KLEP7 ;  Q5X5A8, RUMA_LEGPA ;
DR   A5IBU7, RUMA_LEGPC ;  Q5ZVI4, RUMA_LEGPH ;  Q5WW81, RUMA_LEGPL ;
DR   Q65W13, RUMA_MANSM ;  A1U2U9, RUMA_MARAV ;  Q606W5, RUMA_METCA ;
DR   Q1H069, RUMA_METFK ;  Q2Y6W3, RUMA_NITMU ;  Q3JCY2, RUMA_NITOC ;
DR   Q9CJX3, RUMA_PASMU ;  C6DDJ9, RUMA_PECCP ;  P55136, RUMA_PHOAS ;
DR   Q7N839, RUMA_PHOLL ;  Q6LMS7, RUMA_PHOPR ;  A1VQF1, RUMA_POLNA ;
DR   Q128S1, RUMA_POLSJ ;  B4EUF2, RUMA_PROMH ;  Q48FH7, RUMA_PSE14 ;
DR   Q02I93, RUMA_PSEAB ;  Q9I525, RUMA_PSEAE ;  Q1IDL9, RUMA_PSEE4 ;
DR   Q4K898, RUMA_PSEF5 ;  Q3IDM6, RUMA_PSEHT ;  Q3K8E9, RUMA_PSEPF ;
DR   Q88MB9, RUMA_PSEPK ;  Q885Y8, RUMA_PSESM ;  Q4ZQ44, RUMA_PSEU2 ;
DR   Q4FUU5, RUMA_PSYA2 ;  Q1QDU2, RUMA_PSYCK ;  A1SSB8, RUMA_PSYIN ;
DR   Q1LLI5, RUMA_RALME ;  B2U9U3, RUMA_RALPJ ;  Q8Y035, RUMA_RALSO ;
DR   Q21UR3, RUMA_RHOFD ;  Q9JP88, RUMA_RUBGE ;  Q57KF9, RUMA_SALCH ;
DR   Q5PEJ4, RUMA_SALPA ;  Q8Z446, RUMA_SALTI ;  Q8ZME1, RUMA_SALTY ;
DR   A1S4D3, RUMA_SHEAM ;  B8E8S1, RUMA_SHEB2 ;  A3D7B5, RUMA_SHEB5 ;
DR   A6WR37, RUMA_SHEB8 ;  A9KYI1, RUMA_SHEB9 ;  Q12PZ8, RUMA_SHEDO ;
DR   Q086B4, RUMA_SHEFN ;  B0TK00, RUMA_SHEHH ;  Q8EBQ3, RUMA_SHEON ;
DR   A8H1S1, RUMA_SHEPA ;  A4Y952, RUMA_SHEPC ;  B8CJP2, RUMA_SHEPW ;
DR   A0KU76, RUMA_SHESA ;  A8FSS4, RUMA_SHESH ;  Q0HL77, RUMA_SHESM ;
DR   Q0HXI0, RUMA_SHESR ;  A1RHE4, RUMA_SHESW ;  B1KPU0, RUMA_SHEWM ;
DR   Q31XK5, RUMA_SHIBS ;  Q32CD0, RUMA_SHIDS ;  Q0T1Q1, RUMA_SHIF8 ;
DR   Q83QD5, RUMA_SHIFL ;  Q3YY71, RUMA_SHISS ;  B4SRK6, RUMA_STRM5 ;
DR   B2FPX2, RUMA_STRMK ;  Q3SK67, RUMA_THIDA ;  A1WME3, RUMA_VEREI ;
DR   A5F5I8, RUMA_VIBC3 ;  Q9KPC1, RUMA_VIBCH ;  C3LQZ5, RUMA_VIBCM ;
DR   Q5E320, RUMA_VIBF1 ;  B5FAG4, RUMA_VIBFM ;  A7MTS9, RUMA_VIBHB ;
DR   Q87LP5, RUMA_VIBPA ;  B7VK72, RUMA_VIBSL ;  Q8DC67, RUMA_VIBVU ;
DR   Q7MHP7, RUMA_VIBVY ;  Q8PMU6, RUMA_XANAC ;  Q3BVV1, RUMA_XANC5 ;
DR   Q4USG1, RUMA_XANC8 ;  Q8PB48, RUMA_XANCP ;  Q2P4L7, RUMA_XANOM ;
DR   Q5H1Q8, RUMA_XANOR ;  Q9PAY7, RUMA_XYLFA ;  Q87BR3, RUMA_XYLFT ;
DR   A1JJR0, RUMA_YERE8 ;
//
ID   2.1.1.191
DE   23S rRNA (cytosine(1962)-C(5))-methyltransferase.
AN   rRNA large subunit methyltransferase I.
CA   S-adenosyl-L-methionine + cytosine(1962) in 23S rRNA = S-adenosyl-L-
CA   homocysteine + 5-methylcytosine(1962) in 23S rRNA.
CC   -!- The enzyme specifically methylates cytosine(1962) at C(5) in 23S
CC       rRNA.
DR   A0KKF0, RLMI_AERHH ;  A4SML8, RLMI_AERS4 ;  B6EMK8, RLMI_ALISL ;
DR   B4RRY8, RLMI_ALTMD ;  A8AIB0, RLMI_CITK8 ;  Q482P5, RLMI_COLP3 ;
DR   A7ZK71, RLMI_ECO24 ;  B7UN46, RLMI_ECO27 ;  Q8XD85, RLMI_ECO57 ;
DR   B5YT98, RLMI_ECO5E ;  C4ZQ93, RLMI_ECOBW ;  B1X8S1, RLMI_ECODH ;
DR   A7ZYR9, RLMI_ECOHS ;  A1A9N6, RLMI_ECOK1 ;  Q0TJ93, RLMI_ECOL5 ;
DR   Q8FJ71, RLMI_ECOL6 ;  B1IVW5, RLMI_ECOLC ;  P75876, RLMI_ECOLI ;
DR   B6I942, RLMI_ECOSE ;  B1LJ30, RLMI_ECOSM ;  Q1RDP5, RLMI_ECOUT ;
DR   A4W8X9, RLMI_ENT38 ;  A7ME44, RLMI_ENTS8 ;  B2VDG5, RLMI_ERWT9 ;
DR   B5XY38, RLMI_KLEP3 ;  A6T766, RLMI_KLEP7 ;  Q6LQ36, RLMI_PHOPR ;
DR   Q15TV2, RLMI_PSEA6 ;  Q3IKJ0, RLMI_PSEHT ;  B5F1W3, RLMI_SALA4 ;
DR   A9MHS2, RLMI_SALAR ;  Q57QS3, RLMI_SALCH ;  B5FR09, RLMI_SALDC ;
DR   B5QZH0, RLMI_SALEP ;  B5R6D3, RLMI_SALG2 ;  B4TE06, RLMI_SALHS ;
DR   B4T209, RLMI_SALNS ;  Q5PGB6, RLMI_SALPA ;  A9N6W0, RLMI_SALPB ;
DR   C0Q8C5, RLMI_SALPC ;  B5BBK0, RLMI_SALPK ;  B4TSJ2, RLMI_SALSV ;
DR   Q8Z7R6, RLMI_SALTI ;  Q8ZQ64, RLMI_SALTY ;  A8GCM8, RLMI_SERP5 ;
DR   A1S9W1, RLMI_SHEAM ;  A3D7R1, RLMI_SHEB5 ;  A6WRS8, RLMI_SHEB8 ;
DR   A9L0P6, RLMI_SHEB9 ;  Q12JE5, RLMI_SHEDO ;  Q07VV2, RLMI_SHEFN ;
DR   Q8EHR8, RLMI_SHEON ;  A4Y9L4, RLMI_SHEPC ;  A0KTU3, RLMI_SHESA ;
DR   Q0HLL4, RLMI_SHESM ;  Q0HXZ5, RLMI_SHESR ;  A1RGR7, RLMI_SHESW ;
DR   B2TTS7, RLMI_SHIB3 ;  Q31YN0, RLMI_SHIBS ;  Q32HT9, RLMI_SHIDS ;
DR   Q0T667, RLMI_SHIF8 ;  Q83LM0, RLMI_SHIFL ;  C4L7I7, RLMI_TOLAT ;
DR   A5F8G8, RLMI_VIBC3 ;  Q9KSA5, RLMI_VIBCH ;  Q5E4P6, RLMI_VIBF1 ;
DR   B5FEQ2, RLMI_VIBFM ;  A7MZM6, RLMI_VIBHB ;  Q87P89, RLMI_VIBPA ;
DR   Q8D992, RLMI_VIBVU ;  Q7ML80, RLMI_VIBVY ;  A1JMW5, RLMI_YERE8 ;
DR   A7FJR8, RLMI_YERP3 ;  Q1CA17, RLMI_YERPA ;  B2JYU4, RLMI_YERPB ;
DR   Q7CHM1, RLMI_YERPE ;  A9R2N9, RLMI_YERPG ;  Q1CGL8, RLMI_YERPN ;
DR   A4TKV4, RLMI_YERPP ;  Q66CE0, RLMI_YERPS ;  B1JQP6, RLMI_YERPY ;
//
ID   2.1.1.192
DE   23S rRNA (adenine(2503)-C(2))-methyltransferase.
CA   S-adenosyl-L-methionine + adenine(2503) in 23S rRNA = S-adenosyl-L-
CA   homocysteine + 2-methyladenine(2503) in 23S rRNA.
CC   -!- Contains an [4Fe-4S] cluster.
CC   -!- RlmN is an endogenous enzyme used by the cell to refine functions of
CC       the ribosome in protein synthesis.
CC   -!- cf. EC 2.1.1.194.
DR   Q1DCU1, RLMN1_MYXXD;  B1ZQZ5, RLMN1_OPITP;  Q6MED6, RLMN1_PARUW;
DR   Q1D6I6, RLMN2_MYXXD;  B1ZVM5, RLMN2_OPITP;  Q6MDD0, RLMN2_PARUW;
DR   B2A0B9, RLMN3_OPITP;  B0C9F4, RLMN_ACAM1 ;  A9NEU7, RLMN_ACHLI ;
DR   A1TM24, RLMN_ACIAC ;  Q6FEM6, RLMN_ACIAD ;  B7H072, RLMN_ACIB3 ;
DR   B7I5G4, RLMN_ACIB5 ;  B2I3E2, RLMN_ACIBC ;  Q1IRD1, RLMN_ACIBL ;
DR   B0VKS2, RLMN_ACIBS ;  A3M208, RLMN_ACIBT ;  B0V4U0, RLMN_ACIBY ;
DR   A0LV48, RLMN_ACIC1 ;  A5G209, RLMN_ACICJ ;  A1W574, RLMN_ACISJ ;
DR   A3N1S4, RLMN_ACTP2 ;  B0BQK6, RLMN_ACTPJ ;  A6VQX9, RLMN_ACTSZ ;
DR   A0KJ41, RLMN_AERHH ;  A4SP04, RLMN_AERS4 ;  B9JCI9, RLMN_AGRRK ;
DR   Q7CWI1, RLMN_AGRT5 ;  B9JU97, RLMN_AGRVS ;  B2UNF2, RLMN_AKKM8 ;
DR   Q0VND7, RLMN_ALCBS ;  Q0A989, RLMN_ALHEH ;  B6EGY4, RLMN_ALISL ;
DR   A6TRW3, RLMN_ALKMQ ;  A8MH89, RLMN_ALKOO ;  Q2IIC5, RLMN_ANADE ;
DR   A7HCD6, RLMN_ANADF ;  Q3M9B9, RLMN_ANAVT ;  O66732, RLMN_AQUAE ;
DR   A8EQW8, RLMN_ARCB4 ;  Q5P7B0, RLMN_AROAE ;  A8IQ73, RLMN_AZOC5 ;
DR   A1K3Y6, RLMN_AZOSB ;  A7Z4J5, RLMN_BACA2 ;  C3P635, RLMN_BACAA ;
DR   C3L763, RLMN_BACAC ;  A0RHN7, RLMN_BACAH ;  Q81WH4, RLMN_BACAN ;
DR   B7JJV1, RLMN_BACC0 ;  Q732K6, RLMN_BACC1 ;  B7IUM3, RLMN_BACC2 ;
DR   C1EP88, RLMN_BACC3 ;  B7HDY7, RLMN_BACC4 ;  B7HLJ7, RLMN_BACC7 ;
DR   A7GRJ4, RLMN_BACCN ;  B9IVF3, RLMN_BACCQ ;  Q819U3, RLMN_BACCR ;
DR   Q636G2, RLMN_BACCZ ;  Q5LGK5, RLMN_BACFN ;  Q64XE8, RLMN_BACFR ;
DR   Q9K9Y8, RLMN_BACHD ;  Q6HEV1, RLMN_BACHK ;  Q65JS3, RLMN_BACLD ;
DR   A8FD40, RLMN_BACP2 ;  Q5WKB6, RLMN_BACSK ;  O34617, RLMN_BACSU ;
DR   Q89ZK5, RLMN_BACTN ;  A6L3I9, RLMN_BACV8 ;  A9VTA2, RLMN_BACWK ;
DR   A1UUF7, RLMN_BARBK ;  Q6G592, RLMN_BARHE ;  Q6G1C0, RLMN_BARQU ;
DR   A9IL44, RLMN_BART1 ;  Q6MPV7, RLMN_BDEBA ;  B2IGZ5, RLMN_BEII9 ;
DR   A1A1I4, RLMN_BIFAA ;  Q8G481, RLMN_BIFLO ;  Q492D9, RLMN_BLOPB ;
DR   Q2KY87, RLMN_BORA1 ;  Q7WHM8, RLMN_BORBR ;  Q7W6P5, RLMN_BORPA ;
DR   A9IK57, RLMN_BORPD ;  Q7VWK8, RLMN_BORPE ;  Q89X03, RLMN_BRAJA ;
DR   A5E8P3, RLMN_BRASB ;  A4YJY2, RLMN_BRASO ;  B2S7X6, RLMN_BRUA1 ;
DR   Q2YNV3, RLMN_BRUA2 ;  Q57FT9, RLMN_BRUAB ;  A9M6S9, RLMN_BRUC2 ;
DR   C0RGD9, RLMN_BRUMB ;  Q8YEL1, RLMN_BRUME ;  A5VN22, RLMN_BRUO2 ;
DR   B0CII9, RLMN_BRUSI ;  Q8G374, RLMN_BRUSU ;  P57373, RLMN_BUCAI ;
DR   Q8K9P5, RLMN_BUCAP ;  Q89AK8, RLMN_BUCBP ;  Q057Q1, RLMN_BUCCC ;
DR   B1YR46, RLMN_BURA4 ;  Q1BGX6, RLMN_BURCA ;  B1JT94, RLMN_BURCC ;
DR   A0K7T8, RLMN_BURCH ;  B4EAX1, RLMN_BURCJ ;  Q0BEW5, RLMN_BURCM ;
DR   A3MK77, RLMN_BURM7 ;  A2S2A0, RLMN_BURM9 ;  Q62JW2, RLMN_BURMA ;
DR   A1V4K3, RLMN_BURMS ;  A3NVX3, RLMN_BURP0 ;  Q3JRQ1, RLMN_BURP1 ;
DR   A3NA56, RLMN_BURP6 ;  B2JIV3, RLMN_BURP8 ;  B2SXT2, RLMN_BURPP ;
DR   Q63UT5, RLMN_BURPS ;  Q39FQ7, RLMN_BURS3 ;  Q2SWE6, RLMN_BURTA ;
DR   A4JEP2, RLMN_BURVG ;  Q13X26, RLMN_BURXL ;  A4XL78, RLMN_CALS8 ;
DR   A7ZGB0, RLMN_CAMC1 ;  A7GVW3, RLMN_CAMC5 ;  A0RRU0, RLMN_CAMFF ;
DR   A7I414, RLMN_CAMHC ;  A8FP27, RLMN_CAMJ8 ;  A7H662, RLMN_CAMJD ;
DR   Q0P7R8, RLMN_CAMJE ;  A1W1W6, RLMN_CAMJJ ;  Q5HS83, RLMN_CAMJR ;
DR   B9KEA4, RLMN_CAMLR ;  Q3AC22, RLMN_CARHZ ;  B8GXM4, RLMN_CAUCN ;
DR   Q9ABT6, RLMN_CAUCR ;  B0T387, RLMN_CAUSK ;  A9WFY6, RLMN_CHLAA ;
DR   Q3ASD4, RLMN_CHLCH ;  B3ED49, RLMN_CHLL2 ;  B3EJF5, RLMN_CHLPB ;
DR   A1BGN4, RLMN_CHLPD ;  B3QS43, RLMN_CHLT3 ;  Q8KD71, RLMN_CHLTE ;
DR   Q1QTL1, RLMN_CHRSD ;  Q7NS85, RLMN_CHRVO ;  A8AD69, RLMN_CITK8 ;
DR   Q97IC4, RLMN_CLOAB ;  A7FW72, RLMN_CLOB1 ;  A6LSK1, RLMN_CLOB8 ;
DR   B2V4B5, RLMN_CLOBA ;  B2THS9, RLMN_CLOBB ;  A5I4T4, RLMN_CLOBH ;
DR   B1IIL7, RLMN_CLOBK ;  A7GG92, RLMN_CLOBL ;  B1KX56, RLMN_CLOBM ;
DR   B8I259, RLMN_CLOCE ;  Q182S0, RLMN_CLOD6 ;  A0Q112, RLMN_CLONN ;
DR   Q0TPL4, RLMN_CLOP1 ;  Q8XJL6, RLMN_CLOPE ;  A9KM95, RLMN_CLOPH ;
DR   Q0SS81, RLMN_CLOPS ;  Q895P8, RLMN_CLOTE ;  A3DCX9, RLMN_CLOTH ;
DR   Q47WB7, RLMN_COLP3 ;  Q6NGK9, RLMN_CORDI ;  Q8FP78, RLMN_COREF ;
DR   A4QF26, RLMN_CORGB ;  Q8NP06, RLMN_CORGL ;  Q4JV24, RLMN_CORJK ;
DR   B6J7Q9, RLMN_COXB1 ;  B6IZM7, RLMN_COXB2 ;  A9KFV0, RLMN_COXBN ;
DR   A9NDW2, RLMN_COXBR ;  Q83C77, RLMN_COXBU ;  Q0K959, RLMN_CUPNH ;
DR   Q46ZI0, RLMN_CUPPJ ;  B1WU13, RLMN_CYAA5 ;  B7K4N4, RLMN_CYAP8 ;
DR   Q11QF0, RLMN_CYTH3 ;  Q47BR3, RLMN_DECAR ;  C1CVX7, RLMN_DEIDV ;
DR   Q1J0P9, RLMN_DEIGD ;  Q9RVT6, RLMN_DEIRA ;  A9BMV6, RLMN_DELAS ;
DR   B1I501, RLMN_DESAP ;  Q30X35, RLMN_DESDG ;  B8FS78, RLMN_DESHD ;
DR   Q24U12, RLMN_DESHY ;  C4XTP4, RLMN_DESMR ;  A8ZV25, RLMN_DESOH ;
DR   Q6ALW1, RLMN_DESPS ;  A4J582, RLMN_DESRM ;  Q727F1, RLMN_DESVH ;
DR   B8DRU2, RLMN_DESVM ;  A1VAL8, RLMN_DESVV ;  A5EVN1, RLMN_DICNV ;
DR   B5YF42, RLMN_DICT6 ;  B8E0X3, RLMN_DICTD ;  A8LNF0, RLMN_DINSH ;
DR   A7ZPW0, RLMN_ECO24 ;  B7UGW3, RLMN_ECO27 ;  B7MI02, RLMN_ECO45 ;
DR   B7LDA9, RLMN_ECO55 ;  Q8XAA4, RLMN_ECO57 ;  B5Z0Y6, RLMN_ECO5E ;
DR   B7NRG7, RLMN_ECO7I ;  B7N304, RLMN_ECO81 ;  B7M7M1, RLMN_ECO8A ;
DR   C4ZX92, RLMN_ECOBW ;  B1XAZ2, RLMN_ECODH ;  A8A323, RLMN_ECOHS ;
DR   A1AE55, RLMN_ECOK1 ;  Q0TEW8, RLMN_ECOL5 ;  Q8FF55, RLMN_ECOL6 ;
DR   B1IWE4, RLMN_ECOLC ;  P36979, RLMN_ECOLI ;  B7N6A5, RLMN_ECOLU ;
DR   B6I589, RLMN_ECOSE ;  B1LNH2, RLMN_ECOSM ;  Q1R8L6, RLMN_ECOUT ;
DR   C5BET4, RLMN_EDWI9 ;  A4WD95, RLMN_ENT38 ;  Q833B6, RLMN_ENTFA ;
DR   A7MGV3, RLMN_ENTS8 ;  Q6D273, RLMN_ERWCT ;  B2VE98, RLMN_ERWT9 ;
DR   Q2N9J2, RLMN_ERYLH ;  B7LKC1, RLMN_ESCF3 ;  C4Z523, RLMN_EUBE2 ;
DR   B1YG36, RLMN_EXIS2 ;  A7HNQ1, RLMN_FERNB ;  B0S143, RLMN_FINM2 ;
DR   A5FJ06, RLMN_FLAJ1 ;  A6H1B8, RLMN_FLAPJ ;  Q0RDQ8, RLMN_FRAAA ;
DR   B0U083, RLMN_FRAP2 ;  Q2J713, RLMN_FRASC ;  A8L6D8, RLMN_FRASN ;
DR   Q14HF5, RLMN_FRAT1 ;  A7NC58, RLMN_FRATF ;  Q2A3H3, RLMN_FRATH ;
DR   B2SGH6, RLMN_FRATM ;  A0Q6H0, RLMN_FRATN ;  Q0BLY6, RLMN_FRATO ;
DR   Q5NG03, RLMN_FRATT ;  A4IY03, RLMN_FRATW ;  Q8RFZ9, RLMN_FUSNN ;
DR   C1A949, RLMN_GEMAT ;  Q5L0S1, RLMN_GEOKA ;  Q39S71, RLMN_GEOMG ;
DR   Q74E53, RLMN_GEOSL ;  A4IM49, RLMN_GEOTN ;  A5GEC2, RLMN_GEOUR ;
DR   Q7NIV3, RLMN_GLOVI ;  Q5FUA9, RLMN_GLUOX ;  Q0BV08, RLMN_GRABC ;
DR   A0LY94, RLMN_GRAFK ;  Q7VNZ4, RLMN_HAEDU ;  Q4QNH7, RLMN_HAEI8 ;
DR   A5UAC2, RLMN_HAEIE ;  P44665, RLMN_HAEIN ;  Q0I3U8, RLMN_HAES1 ;
DR   B0UWR0, RLMN_HAES2 ;  Q2SDW1, RLMN_HAHCH ;  A1WXZ3, RLMN_HALHL ;
DR   Q17ZF6, RLMN_HELAH ;  Q7VGY9, RLMN_HELHP ;  B0TGT1, RLMN_HELMI ;
DR   B6JNS0, RLMN_HELP2 ;  B5Z947, RLMN_HELPG ;  Q1CRK2, RLMN_HELPH ;
DR   Q9ZJI4, RLMN_HELPJ ;  B2UVG6, RLMN_HELPS ;  O25970, RLMN_HELPY ;
DR   A9AY55, RLMN_HERA2 ;  A4G4J9, RLMN_HERAR ;  Q0BWY9, RLMN_HYPNA ;
DR   Q5QYC0, RLMN_IDILO ;  A6SZX3, RLMN_JANMA ;  Q28VS6, RLMN_JANSC ;
DR   A6W7W9, RLMN_KINRD ;  B5XNL2, RLMN_KLEP3 ;  A6TCD6, RLMN_KLEP7 ;
DR   B2GJ15, RLMN_KOCRD ;  Q9CJ27, RLMN_LACLA ;  A2RHR3, RLMN_LACLM ;
DR   Q032R6, RLMN_LACLS ;  C1DD41, RLMN_LARHH ;  Q1MQJ3, RLMN_LAWIP ;
DR   Q5X516, RLMN_LEGPA ;  A5IC42, RLMN_LEGPC ;  Q5ZV93, RLMN_LEGPH ;
DR   Q5WWH4, RLMN_LEGPL ;  B0SGA8, RLMN_LEPBA ;  Q04UG1, RLMN_LEPBJ ;
DR   Q04Z14, RLMN_LEPBL ;  B0SPQ8, RLMN_LEPBP ;  B1XXL6, RLMN_LEPCP ;
DR   Q72NP7, RLMN_LEPIC ;  Q8F7V1, RLMN_LEPIN ;  Q92EH6, RLMN_LISIN ;
DR   C1KZZ3, RLMN_LISMC ;  Q723G9, RLMN_LISMF ;  B8DCJ5, RLMN_LISMH ;
DR   Q8Y9P2, RLMN_LISMO ;  A0AFT6, RLMN_LISW6 ;  B1HQE6, RLMN_LYSSC ;
DR   Q2W897, RLMN_MAGSA ;  A0LBZ1, RLMN_MAGSM ;  Q65R87, RLMN_MANSM ;
DR   A1TZP7, RLMN_MARAV ;  Q0ATR3, RLMN_MARMM ;  A6VV03, RLMN_MARMS ;
DR   Q11EE0, RLMN_MESSB ;  Q603C0, RLMN_METCA ;  A9W383, RLMN_METEP ;
DR   Q1H0U6, RLMN_METFK ;  B1ZG98, RLMN_METPB ;  A2SHB8, RLMN_METPP ;
DR   B1M1U6, RLMN_METRJ ;  B0UQR1, RLMN_METS4 ;  B8EIR0, RLMN_METSB ;
DR   B0JT33, RLMN_MICAN ;  Q2RK16, RLMN_MOOTA ;  P0A645, RLMN_MYCBO ;
DR   A1KMM4, RLMN_MYCBP ;  C1AFZ5, RLMN_MYCBT ;  A4TC75, RLMN_MYCGI ;
DR   B2HJP3, RLMN_MYCMM ;  Q73VR8, RLMN_MYCPA ;  Q8EVK0, RLMN_MYCPE ;
DR   A0QVE4, RLMN_MYCS2 ;  A3PXZ7, RLMN_MYCSJ ;  A1UEJ3, RLMN_MYCSK ;
DR   Q1BAG9, RLMN_MYCSS ;  A5U6N5, RLMN_MYCTA ;  P0A644, RLMN_MYCTU ;
DR   A0PQ89, RLMN_MYCUA ;  A1T787, RLMN_MYCVP ;  B2A2K6, RLMN_NATTJ ;
DR   B9L721, RLMN_NAUPA ;  Q5F911, RLMN_NEIG1 ;  B4RMG2, RLMN_NEIG2 ;
DR   A9LZN6, RLMN_NEIM0 ;  A1ISB3, RLMN_NEIMA ;  Q9JZ42, RLMN_NEIMB ;
DR   A1KUD6, RLMN_NEIMF ;  Q0AE39, RLMN_NITEC ;  Q82XV4, RLMN_NITEU ;
DR   Q1QHE3, RLMN_NITHX ;  A9A3L9, RLMN_NITMS ;  Q2Y6F3, RLMN_NITMU ;
DR   Q3JCN4, RLMN_NITOC ;  A6Q115, RLMN_NITSB ;  Q3SNT2, RLMN_NITWN ;
DR   Q5YS67, RLMN_NOCFA ;  A1SLQ4, RLMN_NOCSJ ;  B2J6D0, RLMN_NOSP7 ;
DR   Q8YZV0, RLMN_NOSS1 ;  Q2G8E3, RLMN_NOVAD ;  Q8ELW7, RLMN_OCEIH ;
DR   A6WV17, RLMN_OCHA4 ;  A6L8G0, RLMN_PARD8 ;  A1B4Z8, RLMN_PARDP ;
DR   A7HSW7, RLMN_PARL1 ;  Q9CJJ8, RLMN_PASMU ;  Q3A2Z4, RLMN_PELCD ;
DR   Q3B4B8, RLMN_PELLD ;  B4SA62, RLMN_PELPB ;  A1AL40, RLMN_PELPD ;
DR   A5D1B6, RLMN_PELTS ;  A9BIC0, RLMN_PETMO ;  B4RCA4, RLMN_PHEZH ;
DR   Q7N709, RLMN_PHOLL ;  Q6LU52, RLMN_PHOPR ;  A1VNF1, RLMN_POLNA ;
DR   Q12AB5, RLMN_POLSJ ;  A4SYE2, RLMN_POLSQ ;  B2RMI0, RLMN_PORG3 ;
DR   Q7MTB0, RLMN_PORGI ;  B4S808, RLMN_PROA2 ;  Q6A7K4, RLMN_PROAC ;
DR   A3PEX0, RLMN_PROM0 ;  A2C4M8, RLMN_PROM1 ;  A8G6Y2, RLMN_PROM2 ;
DR   A2C6T3, RLMN_PROM3 ;  A9BCH2, RLMN_PROM4 ;  A2BYK7, RLMN_PROM5 ;
DR   Q318R1, RLMN_PROM9 ;  Q7VA32, RLMN_PROMA ;  B4EZT6, RLMN_PROMH ;
DR   Q7V5P5, RLMN_PROMM ;  Q7V010, RLMN_PROMP ;  A2BT57, RLMN_PROMS ;
DR   Q46J26, RLMN_PROMT ;  A4SEQ5, RLMN_PROVI ;  Q48LZ7, RLMN_PSE14 ;
DR   Q15R53, RLMN_PSEA6 ;  A6V0V7, RLMN_PSEA7 ;  Q02RW0, RLMN_PSEAB ;
DR   Q51385, RLMN_PSEAE ;  Q1IEI4, RLMN_PSEE4 ;  Q4K6U6, RLMN_PSEF5 ;
DR   C3K1L7, RLMN_PSEFS ;  Q3ID16, RLMN_PSEHT ;  A4XY35, RLMN_PSEMY ;
DR   A5VYT2, RLMN_PSEP1 ;  Q3K7B3, RLMN_PSEPF ;  B0KPI4, RLMN_PSEPG ;
DR   Q88PK0, RLMN_PSEPK ;  B1JDQ5, RLMN_PSEPW ;  Q886Z3, RLMN_PSESM ;
DR   Q4ZX26, RLMN_PSEU2 ;  A4VNX4, RLMN_PSEU5 ;  Q4FTX0, RLMN_PSYA2 ;
DR   Q1QD22, RLMN_PSYCK ;  A1SU36, RLMN_PSYIN ;  A5WGQ4, RLMN_PSYWF ;
DR   Q1LLI8, RLMN_RALME ;  B2U9U6, RLMN_RALPJ ;  Q8Y032, RLMN_RALSO ;
DR   B3PQY8, RLMN_RHIE6 ;  Q2K3B1, RLMN_RHIEC ;  Q1MAN2, RLMN_RHIL3 ;
DR   Q98E86, RLMN_RHILO ;  B5ZTF1, RLMN_RHILW ;  Q92L68, RLMN_RHIME ;
DR   C3MAJ1, RLMN_RHISN ;  Q7UHU7, RLMN_RHOBA ;  C0ZY23, RLMN_RHOE4 ;
DR   Q21W25, RLMN_RHOFD ;  C1B2V0, RLMN_RHOOB ;  Q2J405, RLMN_RHOP2 ;
DR   Q07VN5, RLMN_RHOP5 ;  Q6NCS3, RLMN_RHOPA ;  Q21DC2, RLMN_RHOPB ;
DR   Q13D92, RLMN_RHOPS ;  B3Q9D7, RLMN_RHOPT ;  Q2RP22, RLMN_RHORT ;
DR   A3PFQ4, RLMN_RHOS1 ;  Q3IY22, RLMN_RHOS4 ;  A4WNI9, RLMN_RHOS5 ;
DR   B9KQP1, RLMN_RHOSK ;  Q0S277, RLMN_RHOSR ;  A7NPY6, RLMN_ROSCS ;
DR   Q16DM2, RLMN_ROSDO ;  A5UT23, RLMN_ROSS1 ;  Q1AYW0, RLMN_RUBXD ;
DR   A1AW44, RLMN_RUTMC ;  Q21KT6, RLMN_SACD2 ;  A4FMC5, RLMN_SACEN ;
DR   B5F1A0, RLMN_SALA4 ;  A8M6B6, RLMN_SALAI ;  A9MHL3, RLMN_SALAR ;
DR   Q57LI4, RLMN_SALCH ;  B5FR66, RLMN_SALDC ;  B5R584, RLMN_SALEP ;
DR   B5RCZ4, RLMN_SALG2 ;  B4TD95, RLMN_SALHS ;  B4T0Q1, RLMN_SALNS ;
DR   Q5PNI4, RLMN_SALPA ;  A9N1Z8, RLMN_SALPB ;  C0PYM8, RLMN_SALPC ;
DR   B5BAY3, RLMN_SALPK ;  Q2S0P9, RLMN_SALRD ;  B4TR97, RLMN_SALSV ;
DR   Q8Z4P2, RLMN_SALTI ;  A4X4J7, RLMN_SALTO ;  Q8ZN52, RLMN_SALTY ;
DR   A8GHW8, RLMN_SERP5 ;  A1S866, RLMN_SHEAM ;  B8E9S4, RLMN_SHEB2 ;
DR   A3D6W2, RLMN_SHEB5 ;  A6WQQ0, RLMN_SHEB8 ;  A9KXL1, RLMN_SHEB9 ;
DR   Q12PT7, RLMN_SHEDO ;  Q085U9, RLMN_SHEFN ;  B0TLI1, RLMN_SHEHH ;
DR   A3QCF9, RLMN_SHELP ;  Q8EC29, RLMN_SHEON ;  A8H242, RLMN_SHEPA ;
DR   A4Y8U3, RLMN_SHEPC ;  A0KUJ2, RLMN_SHESA ;  A8FT67, RLMN_SHESH ;
DR   Q0HKW2, RLMN_SHESM ;  Q0HX60, RLMN_SHESR ;  A1RHQ0, RLMN_SHESW ;
DR   B1KKI9, RLMN_SHEWM ;  B2TXU2, RLMN_SHIB3 ;  Q31XX3, RLMN_SHIBS ;
DR   Q32D45, RLMN_SHIDS ;  Q0T202, RLMN_SHIF8 ;  Q83K42, RLMN_SHIFL ;
DR   Q3YZ35, RLMN_SHISS ;  Q5LN66, RLMN_SILPO ;  Q1GC70, RLMN_SILST ;
DR   A6UE14, RLMN_SINMW ;  Q2NS37, RLMN_SODGM ;  Q01QF9, RLMN_SOLUE ;
DR   A9FFJ6, RLMN_SORC5 ;  Q1GV98, RLMN_SPHAL ;  A5VAJ8, RLMN_SPHWW ;
DR   Q6XK03, RLMN_SPICI ;  A7X1H8, RLMN_STAA1 ;  A6U137, RLMN_STAA2 ;
DR   Q2FHM0, RLMN_STAA3 ;  Q2FZ66, RLMN_STAA8 ;  A5ISA3, RLMN_STAA9 ;
DR   Q2YXJ8, RLMN_STAAB ;  Q5HGL4, RLMN_STAAC ;  A6QGB8, RLMN_STAAE ;
DR   Q99UQ0, RLMN_STAAM ;  Q7A600, RLMN_STAAN ;  Q6GHL7, RLMN_STAAR ;
DR   Q6G9Z5, RLMN_STAAS ;  A8Z3Q4, RLMN_STAAT ;  Q8NX16, RLMN_STAAW ;
DR   B9DPM7, RLMN_STACT ;  Q5HPX3, RLMN_STAEQ ;  Q8CSW0, RLMN_STAES ;
DR   Q4L5R9, RLMN_STAHJ ;  Q49WZ9, RLMN_STAS1 ;  Q3K2R2, RLMN_STRA1 ;
DR   Q8E6Q7, RLMN_STRA3 ;  Q8E1A3, RLMN_STRA5 ;  Q82JY3, RLMN_STRAW ;
DR   O86754, RLMN_STRCO ;  C0MBZ4, RLMN_STRE4 ;  B4U1T1, RLMN_STREM ;
DR   A8AVZ7, RLMN_STRGC ;  B1VYT2, RLMN_STRGG ;  B4SSW3, RLMN_STRM5 ;
DR   B2FNQ6, RLMN_STRMK ;  Q8DVG8, RLMN_STRMU ;  Q99YU5, RLMN_STRP1 ;
DR   Q04LD5, RLMN_STRP2 ;  P0DF10, RLMN_STRP3 ;  B5E369, RLMN_STRP4 ;
DR   Q5XAZ6, RLMN_STRP6 ;  C1C6B0, RLMN_STRP7 ;  Q8P058, RLMN_STRP8 ;
DR   Q1JAS5, RLMN_STRPB ;  Q1JKX6, RLMN_STRPC ;  Q1JG02, RLMN_STRPD ;
DR   Q1J5R7, RLMN_STRPF ;  A2RDK1, RLMN_STRPG ;  B1IAU3, RLMN_STRPI ;
DR   Q48SK0, RLMN_STRPM ;  Q97RN5, RLMN_STRPN ;  P0DF11, RLMN_STRPQ ;
DR   B2INF0, RLMN_STRPS ;  B5XMB1, RLMN_STRPZ ;  Q8DQG7, RLMN_STRR6 ;
DR   A4W3A5, RLMN_STRS2 ;  C0MD67, RLMN_STRS7 ;  A3CLL3, RLMN_STRSV ;
DR   Q5LY98, RLMN_STRT1 ;  Q5M2V3, RLMN_STRT2 ;  Q03J17, RLMN_STRTD ;
DR   B9DUW7, RLMN_STRU0 ;  C1CJL5, RLMN_STRZP ;  Q30NR4, RLMN_SULDN ;
DR   A6QCU6, RLMN_SULNB ;  Q67PQ7, RLMN_SYMTH ;  Q2LUM5, RLMN_SYNAS ;
DR   Q31MD1, RLMN_SYNE7 ;  A0LQM1, RLMN_SYNFM ;  Q2JRQ8, RLMN_SYNJA ;
DR   Q2JMN2, RLMN_SYNJB ;  B1XQH8, RLMN_SYNP2 ;  Q5MZJ6, RLMN_SYNP6 ;
DR   A5GNG9, RLMN_SYNPW ;  Q7U8K0, RLMN_SYNPX ;  A5GVE8, RLMN_SYNR3 ;
DR   Q0I7M1, RLMN_SYNS3 ;  Q3AZA0, RLMN_SYNS9 ;  Q3AHX9, RLMN_SYNSC ;
DR   Q0AXL8, RLMN_SYNWW ;  Q55880, RLMN_SYNY3 ;  Q8DG98, RLMN_THEEB ;
DR   Q47S46, RLMN_THEFY ;  A8F8C2, RLMN_THELT ;  A6LN47, RLMN_THEM4 ;
DR   Q9X240, RLMN_THEMA ;  B9K7Z6, RLMN_THENN ;  A5ILF6, RLMN_THEP1 ;
DR   B0KA06, RLMN_THEP3 ;  B0K1Y9, RLMN_THEPX ;  B1LAW7, RLMN_THESQ ;
DR   Q72HC1, RLMN_THET2 ;  Q5SGZ3, RLMN_THET8 ;  Q8R9T4, RLMN_THETN ;
DR   Q31I07, RLMN_THICR ;  Q3SL73, RLMN_THIDA ;  C4LC34, RLMN_TOLAT ;
DR   Q73KZ3, RLMN_TREDE ;  O83107, RLMN_TREPA ;  B2S216, RLMN_TREPS ;
DR   Q110I1, RLMN_TRIEI ;  B1H070, RLMN_UNCTG ;  A1WE19, RLMN_VEREI ;
DR   A5CX33, RLMN_VESOH ;  A5F3F8, RLMN_VIBC3 ;  Q9KTX3, RLMN_VIBCH ;
DR   C3LT10, RLMN_VIBCM ;  Q5E775, RLMN_VIBF1 ;  B5FAW9, RLMN_VIBFM ;
DR   A7MU39, RLMN_VIBHB ;  Q87S19, RLMN_VIBPA ;  B7VJT5, RLMN_VIBSL ;
DR   Q8DEZ6, RLMN_VIBVU ;  Q7MNF3, RLMN_VIBVY ;  Q8D1Y5, RLMN_WIGBR ;
DR   Q7MSW1, RLMN_WOLSU ;  Q8PKZ1, RLMN_XANAC ;  Q3BTW5, RLMN_XANC5 ;
DR   Q4UUL5, RLMN_XANC8 ;  B0RT51, RLMN_XANCB ;  Q8P984, RLMN_XANCP ;
DR   Q2P2T0, RLMN_XANOM ;  B2SMB3, RLMN_XANOP ;  Q5GZT3, RLMN_XANOR ;
DR   A7ICB3, RLMN_XANP2 ;  B2I7V5, RLMN_XYLF2 ;  Q9PG43, RLMN_XYLFA ;
DR   B0U494, RLMN_XYLFM ;  Q87B36, RLMN_XYLFT ;  A1JKR9, RLMN_YERE8 ;
DR   A7FFY6, RLMN_YERP3 ;  Q1C5I5, RLMN_YERPA ;  B2K9Q3, RLMN_YERPB ;
DR   Q7CJM9, RLMN_YERPE ;  A9R805, RLMN_YERPG ;  Q1CK94, RLMN_YERPN ;
DR   A4TMU0, RLMN_YERPP ;  Q667Z6, RLMN_YERPS ;  B1JS02, RLMN_YERPY ;
DR   Q5NNQ4, RLMN_ZYMMO ;
//
ID   2.1.1.193
DE   16S rRNA (uracil(1498)-N(3))-methyltransferase.
AN   M(3)U(1498) specific methyltransferase.
CA   S-adenosyl-L-methionine + uracil(1498) in 16S rRNA = S-adenosyl-L-
CA   homocysteine + N(3)-methyluracil(1498) in 16S rRNA.
CC   -!- The enzyme specifically methylates uracil(1498) at N(3) in 16S rRNA.
DR   O51089, RSME1_BORBU;  O51333, RSME2_BORBU;  O66552, RSME_AQUAE ;
DR   P54461, RSME_BACSU ;  P57488, RSME_BUCAI ;  Q8K9E4, RSME_BUCAP ;
DR   P37995, RSME_DICD3 ;  P0AGL8, RSME_ECOL6 ;  P0AGL7, RSME_ECOLI ;
DR   P44627, RSME_HAEIN ;  Q9ZKD2, RSME_HELPJ ;  O25138, RSME_HELPY ;
DR   P67203, RSME_MYCBO ;  O50188, RSME_MYCH2 ;  P67202, RSME_MYCTU ;
DR   Q92J59, RSME_RICCN ;  Q9ZDZ5, RSME_RICPR ;  P0AGL9, RSME_SHIFL ;
DR   P72667, RSME_SYNY3 ;  O83075, RSME_TREPA ;
//
ID   2.1.1.194
DE   23S rRNA (adenine(2503)-C(2),C(8))-methyltransferase.
AN   Cfr rRNA methyltransferase.
CA   2 S-adenosyl-L-methionine + adenine(2503) in 23S rRNA = 2 S-adenosyl-L-
CA   homocysteine + 2,8-methyladenine(2503) in 23S rRNA.
CC   -!- Contains an (4Fe-S) cluster.
CC   -!- Cfr is an plasmid-acquired methyltransferase that protects cells from
CC       the action of antibiotics.
CC   -!- Cfr methylates position 2 of A(2503) after the primary methylation at
CC       position 8 is complete.
CC   -!- cf. EC 2.1.1.192.
DR   A7Z1T2, CFR_BACA2  ;  Q5WJ42, CFR_BACSK  ;  A7FX96, CFR_CLOB1  ;
DR   A5I5U3, CFR_CLOBH  ;  B1IL14, CFR_CLOBK  ;  A7GH77, CFR_CLOBL  ;
DR   B1KZ37, CFR_CLOBM  ;  A9KK15, CFR_CLOPH  ;  A5HBL2, CFR_STAAU  ;
DR   Q9FBG4, CFR_STASC  ;  A2AXI2, CFR_STAWA  ;
//
ID   2.1.1.195
DE   Cobalt-precorrin-5B (C(1))-methyltransferase.
AN   Cobalt-precorrin-6A synthase.
CA   Cobalt-precorrin-5B + S-adenosyl-L-methionine = cobalt-precorrin-6A +
CA   S-adenosyl-L-homocysteine.
CC   -!- This enzyme catylses the C-1 methylation of cobalt-precorrin-5B in
CC       the anaerobic (early cobalt insertion) pathway of adenosylcobalamin
CC       biosynthesis.
//
ID   2.1.1.196
DE   Cobalt-precorrin-7 (C(15))-methyltransferase (decarboxylating).
AN   Cobalt-precorrin-6Y (C(15))-methyltransferase (decarboxylating).
CA   Cobalt-precorrin-7 + S-adenosyl-L-methionine = cobalt-precorrin-8x +
CA   S-adenosyl-L-homocysteine + CO(2).
CC   -!- This enzyme catalyzes both methylation at C-15 and decarboxylation of
CC       the C-12 acetate side chain of cobalt-precorrin-7, a step in the
CC       anaerobic (early cobalt insertion) adenosylcobalamin biosynthesis
CC       pathway.
//
ID   2.1.1.197
DE   Malonyl-CoA O-methyltransferase.
CA   S-adenosyl-L-methionine + malonyl-CoA = S-adenosyl-L-homocysteine +
CA   malonyl-CoA methyl ester.
CC   -!- Involved in an early step of biotin biosynthesis in Gram-negative
CC       bacteria.
CC   -!- This enzyme catalyzes the transfer of a methyl group to the omega-
CC       carboxyl group of malonyl-CoA forming a methyl ester.
CC   -!- The methyl ester is recognized by the fatty acid synthetic enzymes,
CC       which process it via the fatty acid elongation cycle to give pimelyl-
CC       [acyl-carrier-protein] methyl ester.
DR   Q83E64, BIOC1_COXBU;  E3H9W1, BIOC1_ILYPC;  Q83CU8, BIOC2_COXBU;
DR   E3HCT1, BIOC2_ILYPC;  Q2KXN6, BIOCD_BORA1;  Q6FDV0, BIOC_ACIAD ;
DR   Q0VMD3, BIOC_ALCBS ;  B7GHW9, BIOC_ANOFW ;  Q81MB2, BIOC_BACAN ;
DR   A7GSD9, BIOC_BACCN ;  Q818X2, BIOC_BACCR ;  E1WTS2, BIOC_BACF6 ;
DR   Q64VX6, BIOC_BACFR ;  Q9K623, BIOC_BACHD ;  D5DIV9, BIOC_BACMD ;
DR   E6SRF9, BIOC_BACT6 ;  Q8A7S9, BIOC_BACTN ;  C0Z787, BIOC_BREBN ;
DR   Q89AK7, BIOC_BUCBP ;  E4TI44, BIOC_CALNY ;  A3DBD7, BIOC_CLOTH ;
DR   Q47C02, BIOC_DECAR ;  P12999, BIOC_ECOLI ;  E3G327, BIOC_ENTCS ;
DR   D8MPW4, BIOC_ERWBE ;  Q6D3C1, BIOC_ERWCT ;  D2T333, BIOC_ERWP6 ;
DR   O06898, BIOC_ESCVU ;  D9SJ16, BIOC_GALCS ;  Q749W5, BIOC_GEOSL ;
DR   Q7VL11, BIOC_HAEDU ;  P45249, BIOC_HAEIN ;  Q2SBD7, BIOC_HAHCH ;
DR   A1WVM4, BIOC_HALHL ;  C4K5L7, BIOC_HAMD5 ;  A4G5P1, BIOC_HERAR ;
DR   C1D5S5, BIOC_LARHH ;  Q5ZT34, BIOC_LEGPH ;  A0L3L9, BIOC_MAGSM ;
DR   A6W0X8, BIOC_MARMS ;  Q609U9, BIOC_METCA ;  E4QJB8, BIOC_METS6 ;
DR   C6V598, BIOC_NEORI ;  Q2Y9Y6, BIOC_NITMU ;  C6CWS7, BIOC_PAESJ ;
DR   Q3B172, BIOC_PELLD ;  Q7MUB2, BIOC_PORGI ;  B4S687, BIOC_PROA2 ;
DR   A4SGV9, BIOC_PROVI ;  A6UYW3, BIOC_PSEA7 ;  Q21FY5, BIOC_SACD2 ;
DR   Q8ZQQ6, BIOC_SALTY ;  P36571, BIOC_SERMA ;  Q8EDK8, BIOC_SHEON ;
DR   B2IAI0, BIOC_XYLF2 ;  Q7CH67, BIOC_YERPE ;  B3PI89, BIOHC_CELJU;
//
ID   2.1.1.198
DE   16S rRNA (cytidine(1402)-2'-O)-methyltransferase.
CA   S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L-
CA   homocysteine + 2'-O-methylcytosine(1402) in 16S rRNA.
CC   -!- RsmI catalyzes the 2'-O-methylation of cytidine(1402) and RsmH
CC       (EC 2.1.1.199) catalyzes the N(4)-methylation of cytidine(1402) in
CC       16S rRNA.
CC   -!- Both methylations are necessary for efficient translation initiation
CC       at the UUG and GUG codons.
DR   Q9KGL2, RSMI_BACHD ;  P37544, RSMI_BACSU ;  Q661J3, RSMI_BORGA ;
DR   P57192, RSMI_BUCAI ;  Q8KA29, RSMI_BUCAP ;  Q89AY5, RSMI_BUCBP ;
DR   A0RMQ7, RSMI_CAMFF ;  B5Y7N9, RSMI_COPPD ;  P67088, RSMI_ECO57 ;
DR   P67087, RSMI_ECOLI ;  Q2NAK3, RSMI_ERYLH ;  P45298, RSMI_HAEIN ;
DR   Q9ZLS8, RSMI_HELPJ ;  P56204, RSMI_HELPY ;  B4U6H0, RSMI_HYDS0 ;
DR   Q053G0, RSMI_LEPBL ;  B0SPB4, RSMI_LEPBP ;  Q08329, RSMI_MICOL ;
DR   P0A641, RSMI_MYCBO ;  C5J6H5, RSMI_MYCCR ;  P47302, RSMI_MYCGE ;
DR   P75046, RSMI_MYCPN ;  Q98RF5, RSMI_MYCPU ;  P0A640, RSMI_MYCTU ;
DR   Q9JWJ7, RSMI_NEIMA ;  Q9JXE3, RSMI_NEIMB ;  Q9CN04, RSMI_PASMU ;
DR   Q9HVZ3, RSMI_PSEAE ;  Q98DM9, RSMI_RHILO ;  Q9ZCJ3, RSMI_RICPR ;
DR   Q9A186, RSMI_STRP1 ;  P0DF46, RSMI_STRP3 ;  Q5XDL7, RSMI_STRP6 ;
DR   Q8P2A6, RSMI_STRP8 ;  P0DF47, RSMI_STRPQ ;  P74038, RSMI_SYNY3 ;
DR   Q9WZG8, RSMI_THEMA ;  O83940, RSMI_TREPA ;  Q9KUD9, RSMI_VIBCH ;
DR   Q9PFV5, RSMI_XYLFA ;  Q87B70, RSMI_XYLFT ;
//
ID   2.1.1.199
DE   16S rRNA (cytosine(1402)-N(4))-methyltransferase.
CA   S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L-
CA   homocysteine + N(4)-methylcytosine(1402) in 16S rRNA.
CC   -!- RsmH catalyzes the N(4)-methylation of cytosine(1402) and RsmI
CC       (EC 2.1.1.198) catalyzes the 2'-O-methylation of cytosine(1402) in
CC       16S rRNA.
CC   -!- Both methylations are necessary for efficient translation initiation
CC       at the UUG and GUG codons.
DR   A9NFP3, RSMH1_ACHLI;  A6TS69, RSMH1_ALKMQ;  A9KS30, RSMH1_CLOPH;
DR   C4ZBW8, RSMH1_EUBR3;  A9NGP8, RSMH2_ACHLI;  A6TUM7, RSMH2_ALKMQ;
DR   A9KM86, RSMH2_CLOPH;  C4ZD30, RSMH2_EUBR3;  B0BYK8, RSMH_ACAM1 ;
DR   A1TKC3, RSMH_ACIAC ;  Q6F7D1, RSMH_ACIAD ;  B7GVN1, RSMH_ACIB3 ;
DR   B7IAX1, RSMH_ACIB5 ;  B2I0K7, RSMH_ACIBC ;  Q1IKG1, RSMH_ACIBL ;
DR   B0VPF9, RSMH_ACIBS ;  A3M9K5, RSMH_ACIBT ;  B0V8N7, RSMH_ACIBY ;
DR   A0LTL5, RSMH_ACIC1 ;  C1F466, RSMH_ACIC5 ;  A5FUK2, RSMH_ACICJ ;
DR   B9MFS0, RSMH_ACIET ;  B7J3W0, RSMH_ACIF2 ;  B5ELD1, RSMH_ACIF5 ;
DR   A1WC14, RSMH_ACISJ ;  A3MY82, RSMH_ACTP2 ;  B3GZK0, RSMH_ACTP7 ;
DR   B0BRG9, RSMH_ACTPJ ;  A6VQP1, RSMH_ACTSZ ;  A0KPY0, RSMH_AERHH ;
DR   A4SI48, RSMH_AERS4 ;  C6AKG2, RSMH_AGGAN ;  B9JH59, RSMH_AGRRK ;
DR   P58745, RSMH_AGRT5 ;  B9JY62, RSMH_AGRVS ;  Q0VS10, RSMH_ALCBS ;
DR   Q0A6J4, RSMH_ALHEH ;  B6ELI3, RSMH_ALISL ;  A8MH28, RSMH_ALKOO ;
DR   B4RWY7, RSMH_ALTMD ;  B3ESS3, RSMH_AMOA5 ;  B8J8E0, RSMH_ANAD2 ;
DR   Q2IG17, RSMH_ANADE ;  A7HH59, RSMH_ANADF ;  B9KIK0, RSMH_ANAMF ;
DR   Q5PAS3, RSMH_ANAMM ;  Q2GK29, RSMH_ANAPZ ;  B4UER3, RSMH_ANASK ;
DR   B9MQ93, RSMH_ANATD ;  Q3M882, RSMH_ANAVT ;  B7GGJ0, RSMH_ANOFW ;
DR   O67721, RSMH_AQUAE ;  A8EUF3, RSMH_ARCB4 ;  Q5P6Y9, RSMH_AROAE ;
DR   A1R5F0, RSMH_ARTAT ;  B8HGW2, RSMH_ARTCA ;  A0JV86, RSMH_ARTS2 ;
DR   Q2NIH4, RSMH_AYWBP ;  A8HZ68, RSMH_AZOC5 ;  B6YS33, RSMH_AZOPC ;
DR   A1K3T8, RSMH_AZOSB ;  C1DQ91, RSMH_AZOVD ;  A7Z4D7, RSMH_BACA2 ;
DR   C3P688, RSMH_BACAA ;  C3L6F3, RSMH_BACAC ;  A0RHT9, RSMH_BACAH ;
DR   Q81WC3, RSMH_BACAN ;  B7JK06, RSMH_BACC0 ;  P62468, RSMH_BACC1 ;
DR   B7IVF3, RSMH_BACC2 ;  C1EPT2, RSMH_BACC3 ;  B7H6Q4, RSMH_BACC4 ;
DR   B7HM39, RSMH_BACC7 ;  A7GRP4, RSMH_BACCN ;  B9IVZ5, RSMH_BACCQ ;
DR   Q819P8, RSMH_BACCR ;  Q636A8, RSMH_BACCZ ;  Q5LIJ0, RSMH_BACFN ;
DR   Q64ZL4, RSMH_BACFR ;  Q9K9S0, RSMH_BACHD ;  Q6HEP6, RSMH_BACHK ;
DR   Q65JY8, RSMH_BACLD ;  A8FCX3, RSMH_BACP2 ;  Q5WFG1, RSMH_BACSK ;
DR   Q07876, RSMH_BACSU ;  Q8A251, RSMH_BACTN ;  A6L078, RSMH_BACV8 ;
DR   A9VU80, RSMH_BACWK ;  A1UTD3, RSMH_BARBK ;  C6AEK6, RSMH_BARGA ;
DR   Q6G2P7, RSMH_BARHE ;  Q6G116, RSMH_BARQU ;  A9IWB6, RSMH_BART1 ;
DR   Q1LSW0, RSMH_BAUCH ;  P62469, RSMH_BDEBA ;  B2IGF2, RSMH_BEII9 ;
DR   C5BW67, RSMH_BEUC1 ;  B8DSU7, RSMH_BIFA0 ;  A1A2F7, RSMH_BIFAA ;
DR   C6AJH2, RSMH_BIFAS ;  C6A8W4, RSMH_BIFLB ;  B3DQM3, RSMH_BIFLD ;
DR   Q8G4R0, RSMH_BIFLO ;  B7GQ70, RSMH_BIFLS ;  Q7VQJ5, RSMH_BLOFL ;
DR   Q493Q9, RSMH_BLOPB ;  Q2KVE4, RSMH_BORA1 ;  Q0SNK4, RSMH_BORAP ;
DR   Q7WFR5, RSMH_BORBR ;  O51286, RSMH_BORBU ;  B7J1N4, RSMH_BORBZ ;
DR   B5RLD2, RSMH_BORDL ;  Q661V8, RSMH_BORGA ;  B2S017, RSMH_BORHD ;
DR   Q7W4A7, RSMH_BORPA ;  A9I4S5, RSMH_BORPD ;  Q7VUP6, RSMH_BORPE ;
DR   B5RRC5, RSMH_BORRA ;  A1QZA2, RSMH_BORT9 ;  C0QWF7, RSMH_BRAHW ;
DR   Q89FT9, RSMH_BRAJA ;  A5EPL2, RSMH_BRASB ;  A4YZL1, RSMH_BRASO ;
DR   C0ZGB3, RSMH_BREBN ;  B2S6R2, RSMH_BRUA1 ;  Q2YM63, RSMH_BRUA2 ;
DR   Q57C70, RSMH_BRUAB ;  A9M698, RSMH_BRUC2 ;  C0RE78, RSMH_BRUMB ;
DR   P65427, RSMH_BRUME ;  A5VRI5, RSMH_BRUO2 ;  B0CHM8, RSMH_BRUSI ;
DR   P65428, RSMH_BRUSU ;  B8D922, RSMH_BUCA5 ;  P57319, RSMH_BUCAI ;
DR   O85295, RSMH_BUCAP ;  B8D7C6, RSMH_BUCAT ;  P59522, RSMH_BUCBP ;
DR   Q057T6, RSMH_BUCCC ;  B1YSR6, RSMH_BURA4 ;  Q1BZH1, RSMH_BURCA ;
DR   B1JUW4, RSMH_BURCC ;  A0K478, RSMH_BURCH ;  B4E6K0, RSMH_BURCJ ;
DR   Q0BIK9, RSMH_BURCM ;  A9AJ24, RSMH_BURM1 ;  A3MR55, RSMH_BURM7 ;
DR   A2S5V3, RSMH_BURM9 ;  Q62GR9, RSMH_BURMA ;  A1V0S6, RSMH_BURMS ;
DR   A3NZM3, RSMH_BURP0 ;  Q3JND0, RSMH_BURP1 ;  A3NDX2, RSMH_BURP6 ;
DR   B2JHG8, RSMH_BURP8 ;  B2SYY3, RSMH_BURPP ;  Q63QI9, RSMH_BURPS ;
DR   Q39JX8, RSMH_BURS3 ;  Q2SZJ1, RSMH_BURTA ;  A4JB86, RSMH_BURVG ;
DR   Q13TY4, RSMH_BURXL ;  A4XHZ6, RSMH_CALS8 ;  A7ZD05, RSMH_CAMC1 ;
DR   A7GYX6, RSMH_CAMC5 ;  A0RNH4, RSMH_CAMFF ;  A7I1J3, RSMH_CAMHC ;
DR   A8FLC2, RSMH_CAMJ8 ;  A7H4D2, RSMH_CAMJD ;  Q9PPL4, RSMH_CAMJE ;
DR   A1VZ48, RSMH_CAMJJ ;  Q5HV88, RSMH_CAMJR ;  B9KD58, RSMH_CAMLR ;
DR   Q3AAD7, RSMH_CARHZ ;  B8H0A2, RSMH_CAUCN ;  Q9RQJ6, RSMH_CAUCR ;
DR   B0T839, RSMH_CAUSK ;  B3PCM8, RSMH_CELJU ;  A9WG80, RSMH_CHLAA ;
DR   Q5L6B5, RSMH_CHLAB ;  B8G5X3, RSMH_CHLAD ;  Q3ANW1, RSMH_CHLCH ;
DR   Q823N6, RSMH_CHLCV ;  Q253Y0, RSMH_CHLFF ;  B3EIL6, RSMH_CHLL2 ;
DR   Q9PKC2, RSMH_CHLMU ;  B3QLX2, RSMH_CHLP8 ;  B3EQC6, RSMH_CHLPB ;
DR   A1BJY6, RSMH_CHLPD ;  Q9Z8C2, RSMH_CHLPN ;  B9LKK0, RSMH_CHLSY ;
DR   B0B7I8, RSMH_CHLT2 ;  B3QWS9, RSMH_CHLT3 ;  Q3KM90, RSMH_CHLTA ;
DR   B0BBQ3, RSMH_CHLTB ;  Q8KGC6, RSMH_CHLTE ;  O84274, RSMH_CHLTR ;
DR   Q1QVF9, RSMH_CHRSD ;  Q7NPZ1, RSMH_CHRVO ;  A8ALL4, RSMH_CITK8 ;
DR   A5CS59, RSMH_CLAM3 ;  B0RI49, RSMH_CLAMS ;  Q97H81, RSMH_CLOAB ;
DR   A7FTX8, RSMH_CLOB1 ;  C3KV90, RSMH_CLOB6 ;  A6LTS0, RSMH_CLOB8 ;
DR   B2V4W0, RSMH_CLOBA ;  B2TS30, RSMH_CLOBB ;  A5I1T3, RSMH_CLOBH ;
DR   C1FME6, RSMH_CLOBJ ;  B1IKR0, RSMH_CLOBK ;  A7GDE2, RSMH_CLOBL ;
DR   B1L164, RSMH_CLOBM ;  B8I6G6, RSMH_CLOCE ;  Q182Z2, RSMH_CLOD6 ;
DR   B9E0V5, RSMH_CLOK1 ;  A0Q055, RSMH_CLONN ;  Q0TP92, RSMH_CLOP1 ;
DR   Q8XJ96, RSMH_CLOPE ;  Q0SRV9, RSMH_CLOPS ;  Q894B4, RSMH_CLOTE ;
DR   A3DE34, RSMH_CLOTH ;  Q47VQ1, RSMH_COLP3 ;  B5Y8C1, RSMH_COPPD ;
DR   C3PHG4, RSMH_CORA7 ;  P60395, RSMH_CORDI ;  Q8FNT2, RSMH_COREF ;
DR   A4QFN1, RSMH_CORGB ;  Q8NNM7, RSMH_CORGL ;  Q4JWA3, RSMH_CORJK ;
DR   C4LI42, RSMH_CORK4 ;  B1VHD2, RSMH_CORU7 ;  B6J5L7, RSMH_COXB1 ;
DR   B6J2R7, RSMH_COXB2 ;  A9KET2, RSMH_COXBN ;  A9NA25, RSMH_COXBR ;
DR   Q83F35, RSMH_COXBU ;  Q0K6L6, RSMH_CUPNH ;  Q46WY6, RSMH_CUPPJ ;
DR   B3R6W7, RSMH_CUPTR ;  B1WZ70, RSMH_CYAA5 ;  B8HTI9, RSMH_CYAP4 ;
DR   B7K9F0, RSMH_CYAP7 ;  B7K639, RSMH_CYAP8 ;  Q11RG6, RSMH_CYTH3 ;
DR   Q47A96, RSMH_DECAR ;  Q3Z9L1, RSMH_DEHE1 ;  A5FSB7, RSMH_DEHSB ;
DR   Q3ZZA4, RSMH_DEHSC ;  C1D1L8, RSMH_DEIDV ;  Q1J0B6, RSMH_DEIGD ;
DR   Q9RT99, RSMH_DEIRA ;  A9BUJ8, RSMH_DELAS ;  B8FBS6, RSMH_DESAA ;
DR   C6BYH4, RSMH_DESAD ;  C0Q8N5, RSMH_DESAH ;  B1I4D9, RSMH_DESAP ;
DR   B8IZT3, RSMH_DESDA ;  Q313R1, RSMH_DESDG ;  B8FT64, RSMH_DESHD ;
DR   Q24TD8, RSMH_DESHY ;  C4XK86, RSMH_DESMR ;  A8ZXX1, RSMH_DESOH ;
DR   Q6AJ47, RSMH_DESPS ;  A4J2A3, RSMH_DESRM ;  P62470, RSMH_DESVH ;
DR   B8DP86, RSMH_DESVM ;  A1VBE0, RSMH_DESVV ;  C6C9K0, RSMH_DICDC ;
DR   A5EY11, RSMH_DICNV ;  B5YEM1, RSMH_DICT6 ;  B8E088, RSMH_DICTD ;
DR   C6CJW6, RSMH_DICZE ;  A8LSB5, RSMH_DINSH ;  A7ZHH3, RSMH_ECO24 ;
DR   B7UID2, RSMH_ECO27 ;  B7MAK5, RSMH_ECO45 ;  B7LFV2, RSMH_ECO55 ;
DR   P60391, RSMH_ECO57 ;  B5YZB8, RSMH_ECO5E ;  B7NHI8, RSMH_ECO7I ;
DR   B7MNU1, RSMH_ECO81 ;  B7M125, RSMH_ECO8A ;  C5W331, RSMH_ECOBD ;
DR   C6UM45, RSMH_ECOBR ;  C4ZQ04, RSMH_ECOBW ;  B1XC59, RSMH_ECODH ;
DR   A7ZW34, RSMH_ECOHS ;  A1A7C7, RSMH_ECOK1 ;  Q0TLQ7, RSMH_ECOL5 ;
DR   Q8FL68, RSMH_ECOL6 ;  B1IR96, RSMH_ECOLC ;  P60390, RSMH_ECOLI ;
DR   B7N7V5, RSMH_ECOLU ;  B6HZ59, RSMH_ECOSE ;  B1LG19, RSMH_ECOSM ;
DR   Q1RGB3, RSMH_ECOUT ;  C5B9E8, RSMH_EDWI9 ;  Q3YRX7, RSMH_EHRCJ ;
DR   Q2GGS8, RSMH_EHRCR ;  Q5FH93, RSMH_EHRRG ;  Q5HB44, RSMH_EHRRW ;
DR   B2KE60, RSMH_ELUMP ;  A4W6I5, RSMH_ENT38 ;  O07104, RSMH_ENTFA ;
DR   O07665, RSMH_ENTHR ;  A7MIE1, RSMH_ENTS8 ;  Q6D0H5, RSMH_ERWCT ;
DR   B2VD83, RSMH_ERWT9 ;  Q2NCZ8, RSMH_ERYLH ;  B7LWH0, RSMH_ESCF3 ;
DR   C4Z530, RSMH_EUBE2 ;  B1YIU3, RSMH_EXIS2 ;  C4L5T9, RSMH_EXISA ;
DR   A7HNY7, RSMH_FERNB ;  B0S0Y9, RSMH_FINM2 ;  A5FIX6, RSMH_FLAJ1 ;
DR   A6H1A2, RSMH_FLAPJ ;  Q0RNP9, RSMH_FRAAA ;  B0TZ13, RSMH_FRAP2 ;
DR   Q2JD58, RSMH_FRASC ;  A8KZA9, RSMH_FRASN ;  Q14ID3, RSMH_FRAT1 ;
DR   A7NDP7, RSMH_FRATF ;  Q2A265, RSMH_FRATH ;  B2SDL2, RSMH_FRATM ;
DR   A0Q5I5, RSMH_FRATN ;  Q0BKT7, RSMH_FRATO ;  Q5NGY1, RSMH_FRATT ;
DR   A4IZB0, RSMH_FRATW ;  Q8R6F5, RSMH_FUSNN ;  C1A8A2, RSMH_GEMAT ;
DR   B5EBP3, RSMH_GEOBB ;  Q5L0Y4, RSMH_GEOKA ;  B3E3Z0, RSMH_GEOLS ;
DR   Q39YM7, RSMH_GEOMG ;  B9M164, RSMH_GEOSF ;  P60396, RSMH_GEOSL ;
DR   C6DZJ8, RSMH_GEOSM ;  C5D8L5, RSMH_GEOSW ;  A4IM00, RSMH_GEOTN ;
DR   A5G8K8, RSMH_GEOUR ;  Q7NCQ1, RSMH_GLOVI ;  A9H0G9, RSMH_GLUDA ;
DR   Q5FUK3, RSMH_GLUOX ;  Q0BV17, RSMH_GRABC ;  A0M534, RSMH_GRAFK ;
DR   Q7VP62, RSMH_HAEDU ;  Q4QLG6, RSMH_HAEI8 ;  A5UCX6, RSMH_HAEIE ;
DR   A5UIQ3, RSMH_HAEIG ;  P45057, RSMH_HAEIN ;  B8F3A8, RSMH_HAEPS ;
DR   Q0I1E1, RSMH_HAES1 ;  B0US59, RSMH_HAES2 ;  Q2S9Y4, RSMH_HAHCH ;
DR   A1WYV1, RSMH_HALHL ;  B8CWI8, RSMH_HALOH ;  C4K744, RSMH_HAMD5 ;
DR   Q17XC0, RSMH_HELAH ;  Q7VGP1, RSMH_HELHP ;  B0TGB2, RSMH_HELMI ;
DR   Q8GE08, RSMH_HELMO ;  B6JLU2, RSMH_HELP2 ;  C7BZ94, RSMH_HELPB ;
DR   B5Z772, RSMH_HELPG ;  Q1CTG3, RSMH_HELPH ;  Q9ZLD4, RSMH_HELPJ ;
DR   B2UTC1, RSMH_HELPS ;  O25411, RSMH_HELPY ;  A9B518, RSMH_HERA2 ;
DR   A4G8U6, RSMH_HERAR ;  B4U8T1, RSMH_HYDS0 ;  Q0BXT4, RSMH_HYPNA ;
DR   Q5R0L7, RSMH_IDILO ;  A6T2G6, RSMH_JANMA ;  Q28NM6, RSMH_JANSC ;
DR   A6WCY2, RSMH_KINRD ;  B5Y1V5, RSMH_KLEP3 ;  A6T4M5, RSMH_KLEP7 ;
DR   B2GJQ6, RSMH_KOCRD ;  C5CGS3, RSMH_KOSOT ;  Q5FKV7, RSMH_LACAC ;
DR   Q03QH0, RSMH_LACBA ;  Q039S2, RSMH_LACC3 ;  B3WDX7, RSMH_LACCB ;
DR   Q1GAU0, RSMH_LACDA ;  Q04B77, RSMH_LACDB ;  B2GB73, RSMH_LACF3 ;
DR   Q042P4, RSMH_LACGA ;  A8YUN6, RSMH_LACH4 ;  P62471, RSMH_LACJO ;
DR   Q9CH73, RSMH_LACLA ;  A2RLT4, RSMH_LACLM ;  Q02ZY9, RSMH_LACLS ;
DR   Q88V76, RSMH_LACPL ;  A5VJ28, RSMH_LACRD ;  B2G6K1, RSMH_LACRJ ;
DR   Q1WT95, RSMH_LACS1 ;  Q38XN3, RSMH_LACSS ;  C1D5M5, RSMH_LARHH ;
DR   Q1MPC6, RSMH_LAWIP ;  Q5X6J0, RSMH_LEGPA ;  A5IFZ9, RSMH_LEGPC ;
DR   Q5ZX19, RSMH_LEGPH ;  Q5WXZ4, RSMH_LEGPL ;  Q6AE56, RSMH_LEIXX ;
DR   B0S989, RSMH_LEPBA ;  Q04V89, RSMH_LEPBJ ;  Q04Y87, RSMH_LEPBL ;
DR   B0SRS3, RSMH_LEPBP ;  B1XY20, RSMH_LEPCP ;  P62472, RSMH_LEPIC ;
DR   Q8F4J6, RSMH_LEPIN ;  B1MXV5, RSMH_LEUCK ;  Q03W30, RSMH_LEUMM ;
DR   Q929X6, RSMH_LISIN ;  C1KWZ4, RSMH_LISMC ;  Q71XX2, RSMH_LISMF ;
DR   B8DH88, RSMH_LISMH ;  Q8Y5L7, RSMH_LISMO ;  A0AKE1, RSMH_LISW6 ;
DR   B1HPY0, RSMH_LYSSC ;  B9EB47, RSMH_MACCJ ;  Q2W0I1, RSMH_MAGSA ;
DR   A0L5N9, RSMH_MAGSM ;  Q65RX8, RSMH_MANSM ;  A1U3G6, RSMH_MARAV ;
DR   Q0AMV9, RSMH_MARMM ;  A6VYK6, RSMH_MARMS ;  Q6F170, RSMH_MESFL ;
DR   Q11GR7, RSMH_MESSB ;  B7KU77, RSMH_METC4 ;  Q604V0, RSMH_METCA ;
DR   C5ATZ5, RSMH_METEA ;  A9VW37, RSMH_METEP ;  Q1GYZ3, RSMH_METFK ;
DR   B3DVX0, RSMH_METI4 ;  B8IMX2, RSMH_METNO ;  B1Z8U3, RSMH_METPB ;
DR   A2SCX7, RSMH_METPP ;  B1LYT9, RSMH_METRJ ;  B0UFI0, RSMH_METS4 ;
DR   B8ETL4, RSMH_METSB ;  B0JKS7, RSMH_MICAN ;  C5CA38, RSMH_MICLC ;
DR   Q2RK87, RSMH_MOOTA ;  A0QF44, RSMH_MYCA1 ;  B3PMB4, RSMH_MYCA5 ;
DR   B1MP29, RSMH_MYCA9 ;  A5IYG2, RSMH_MYCAP ;  P65430, RSMH_MYCBO ;
DR   A1KKK8, RSMH_MYCBP ;  C1AQ81, RSMH_MYCBT ;  C5J697, RSMH_MYCCR ;
DR   Q2SS95, RSMH_MYCCT ;  Q7NB79, RSMH_MYCGA ;  P47464, RSMH_MYCGE ;
DR   A4TBF6, RSMH_MYCGI ;  Q600P9, RSMH_MYCH2 ;  Q4A7X8, RSMH_MYCH7 ;
DR   Q4A9T0, RSMH_MYCHJ ;  B8ZQP2, RSMH_MYCLB ;  O69560, RSMH_MYCLE ;
DR   B2HGS5, RSMH_MYCMM ;  Q6KHR2, RSMH_MYCMO ;  P62473, RSMH_MYCMS ;
DR   P62474, RSMH_MYCPA ;  Q8EW81, RSMH_MYCPE ;  P75466, RSMH_MYCPN ;
DR   Q98Q75, RSMH_MYCPU ;  A0R024, RSMH_MYCS2 ;  Q4A667, RSMH_MYCS5 ;
DR   A3Q1M6, RSMH_MYCSJ ;  A1UI62, RSMH_MYCSK ;  Q1B6W3, RSMH_MYCSS ;
DR   A5U4J2, RSMH_MYCTA ;  P65429, RSMH_MYCTU ;  A0PTJ6, RSMH_MYCUA ;
DR   A1TAX6, RSMH_MYCVP ;  Q1D0S2, RSMH_MYXXD ;  B2A2G4, RSMH_NATTJ ;
DR   B9L9G3, RSMH_NAUPA ;  Q5F6K7, RSMH_NEIG1 ;  B4RQD7, RSMH_NEIG2 ;
DR   A9M2I4, RSMH_NEIM0 ;  Q9JSY9, RSMH_NEIMA ;  Q9K0Z0, RSMH_NEIMB ;
DR   A1KVM4, RSMH_NEIMF ;  Q2GCL1, RSMH_NEOSM ;  Q0AJD3, RSMH_NITEC ;
DR   Q82VT1, RSMH_NITEU ;  Q1QNV1, RSMH_NITHX ;  Q2Y630, RSMH_NITMU ;
DR   Q3J781, RSMH_NITOC ;  A6Q3T0, RSMH_NITSB ;  Q3STT6, RSMH_NITWN ;
DR   Q5YYY7, RSMH_NOCFA ;  A1SL88, RSMH_NOCSJ ;  B2J183, RSMH_NOSP7 ;
DR   Q8YRT9, RSMH_NOSS1 ;  Q2G9A3, RSMH_NOVAD ;  Q8ER53, RSMH_OCEIH ;
DR   A6WZP8, RSMH_OCHA4 ;  Q04ES5, RSMH_OENOB ;  B6JCF0, RSMH_OLICO ;
DR   P60397, RSMH_ONYPE ;  B1ZU25, RSMH_OPITP ;  A5CD85, RSMH_ORITB ;
DR   B3CVD8, RSMH_ORITI ;  C6D563, RSMH_PAESJ ;  A6LEV0, RSMH_PARD8 ;
DR   A1AZK1, RSMH_PARDP ;  A7HVT9, RSMH_PARL1 ;  Q6MEG4, RSMH_PARUW ;
DR   Q9CPB4, RSMH_PASMU ;  C6DEV1, RSMH_PECCP ;  Q03EX7, RSMH_PEDPA ;
DR   Q3A2F8, RSMH_PELCD ;  Q3B121, RSMH_PELLD ;  B4SHF1, RSMH_PELPB ;
DR   A1AU69, RSMH_PELPD ;  A5D113, RSMH_PELTS ;  Q4FPN5, RSMH_PELUB ;
DR   C0QP68, RSMH_PERMH ;  A9BHH9, RSMH_PETMO ;  B4RFS8, RSMH_PHEZH ;
DR   Q7N139, RSMH_PHOLL ;  P62475, RSMH_PHOPR ;  B1V910, RSMH_PHYAS ;
DR   B3R0Q2, RSMH_PHYMT ;  A1VSU4, RSMH_POLNA ;  B1XT01, RSMH_POLNS ;
DR   Q12EM3, RSMH_POLSJ ;  A4SV66, RSMH_POLSQ ;  B2RIE4, RSMH_PORG3 ;
DR   Q7MWN0, RSMH_PORGI ;  B4S6R7, RSMH_PROA2 ;  Q6A9R0, RSMH_PROAC ;
DR   A3PAN9, RSMH_PROM0 ;  A2C000, RSMH_PROM1 ;  A8G2H7, RSMH_PROM2 ;
DR   A2CD93, RSMH_PROM3 ;  A9BD32, RSMH_PROM4 ;  A2BUE8, RSMH_PROM5 ;
DR   Q31D10, RSMH_PROM9 ;  Q7VE18, RSMH_PROMA ;  B4F119, RSMH_PROMH ;
DR   Q7V4B2, RSMH_PROMM ;  Q7V3B1, RSMH_PROMP ;  A2BNW6, RSMH_PROMS ;
DR   Q46HK1, RSMH_PROMT ;  A4SH10, RSMH_PROVI ;  Q48EF0, RSMH_PSE14 ;
DR   Q15Q09, RSMH_PSEA6 ;  A6VB93, RSMH_PSEA7 ;  B7UZJ8, RSMH_PSEA8 ;
DR   Q02H20, RSMH_PSEAB ;  Q9HVZ5, RSMH_PSEAE ;  Q1I5B0, RSMH_PSEE4 ;
DR   Q4K6I5, RSMH_PSEF5 ;  C3KCS2, RSMH_PSEFS ;  Q3IFZ6, RSMH_PSEHT ;
DR   A4XQR6, RSMH_PSEMY ;  A5W8Q8, RSMH_PSEP1 ;  Q3K736, RSMH_PSEPF ;
DR   B0KFT4, RSMH_PSEPG ;  Q88N84, RSMH_PSEPK ;  B1J1Y2, RSMH_PSEPW ;
DR   Q87WX7, RSMH_PSESM ;  Q4ZNY2, RSMH_PSEU2 ;  A4VIH0, RSMH_PSEU5 ;
DR   Q4FQ05, RSMH_PSYA2 ;  Q1Q846, RSMH_PSYCK ;  A1SU11, RSMH_PSYIN ;
DR   A5WBQ1, RSMH_PSYWF ;  Q1LIL8, RSMH_RALME ;  C6BEJ1, RSMH_RALP1 ;
DR   B2UCY5, RSMH_RALPJ ;  Q8XVH9, RSMH_RALSO ;  A9WRE6, RSMH_RENSM ;
DR   B3PTW8, RSMH_RHIE6 ;  Q2K6B3, RSMH_RHIEC ;  Q1ME25, RSMH_RHIL3 ;
DR   Q98KA5, RSMH_RHILO ;  C6ARU7, RSMH_RHILS ;  B5ZWK2, RSMH_RHILW ;
DR   Q92NL4, RSMH_RHIME ;  C3MEN7, RSMH_RHISN ;  Q7UFX8, RSMH_RHOBA ;
DR   B6IRH0, RSMH_RHOCS ;  C1A0Y3, RSMH_RHOE4 ;  Q21SW1, RSMH_RHOFD ;
DR   C1AU63, RSMH_RHOOB ;  Q2IYL6, RSMH_RHOP2 ;  Q07PU1, RSMH_RHOP5 ;
DR   P60398, RSMH_RHOPA ;  Q216E6, RSMH_RHOPB ;  Q133W3, RSMH_RHOPS ;
DR   B3QFN9, RSMH_RHOPT ;  Q2RVT6, RSMH_RHORT ;  A3PHR7, RSMH_RHOS1 ;
DR   Q3J4N3, RSMH_RHOS4 ;  A4WQC5, RSMH_RHOS5 ;  B9KNI8, RSMH_RHOSK ;
DR   Q0SHR3, RSMH_RHOSR ;  C3PNZ9, RSMH_RICAE ;  A8GP28, RSMH_RICAH ;
DR   A8GVV6, RSMH_RICB8 ;  Q1RJ43, RSMH_RICBR ;  A8EYC5, RSMH_RICCK ;
DR   Q92HB4, RSMH_RICCN ;  Q4UL18, RSMH_RICFE ;  A8F247, RSMH_RICM5 ;
DR   Q9ZCY2, RSMH_RICPR ;  C4K1M0, RSMH_RICPU ;  B0BYA0, RSMH_RICRO ;
DR   A8GSS6, RSMH_RICRS ;  Q68WG7, RSMH_RICTY ;  A7NIA2, RSMH_ROSCS ;
DR   Q163I0, RSMH_ROSDO ;  A5UZS9, RSMH_ROSS1 ;  Q1AVW6, RSMH_RUBXD ;
DR   A1AVX1, RSMH_RUTMC ;  Q21MH7, RSMH_SACD2 ;  A4FLX5, RSMH_SACEN ;
DR   B5F7V6, RSMH_SALA4 ;  A8LX88, RSMH_SALAI ;  A9MQD1, RSMH_SALAR ;
DR   Q57TD8, RSMH_SALCH ;  B5FI64, RSMH_SALDC ;  B5R2L6, RSMH_SALEP ;
DR   B5RH56, RSMH_SALG2 ;  B4TJ79, RSMH_SALHS ;  B4SU42, RSMH_SALNS ;
DR   Q5PDH4, RSMH_SALPA ;  A9MZL1, RSMH_SALPB ;  C0Q5H8, RSMH_SALPC ;
DR   B5BLG4, RSMH_SALPK ;  Q2S535, RSMH_SALRD ;  B4TXH0, RSMH_SALSV ;
DR   Q8Z9H4, RSMH_SALTI ;  A4X9S3, RSMH_SALTO ;  Q8ZRU8, RSMH_SALTY ;
DR   A8G9R9, RSMH_SERP5 ;  A1S2F1, RSMH_SHEAM ;  B8E4L2, RSMH_SHEB2 ;
DR   A3CZL3, RSMH_SHEB5 ;  A6WIC3, RSMH_SHEB8 ;  A9KY21, RSMH_SHEB9 ;
DR   Q12SD4, RSMH_SHEDO ;  Q07WH7, RSMH_SHEFN ;  B0TQM9, RSMH_SHEHH ;
DR   A3QIM9, RSMH_SHELP ;  Q8E9P0, RSMH_SHEON ;  A8H992, RSMH_SHEPA ;
DR   A4Y2M8, RSMH_SHEPC ;  B8CM48, RSMH_SHEPW ;  A0L1Q0, RSMH_SHESA ;
DR   A8FQ92, RSMH_SHESH ;  Q0HE75, RSMH_SHESM ;  Q0HZS4, RSMH_SHESR ;
DR   A1REY8, RSMH_SHESW ;  Q9F1N8, RSMH_SHEVD ;  B1KKY5, RSMH_SHEWM ;
DR   B2U287, RSMH_SHIB3 ;  Q326F3, RSMH_SHIBS ;  Q32K10, RSMH_SHIDS ;
DR   Q0T8B5, RSMH_SHIF8 ;  Q83SN7, RSMH_SHIFL ;  Q3Z5S7, RSMH_SHISS ;
DR   Q5LU79, RSMH_SILPO ;  Q1GF19, RSMH_SILST ;  A6UB93, RSMH_SINMW ;
DR   Q2NVV9, RSMH_SODGM ;  Q01Q40, RSMH_SOLUE ;  A9FI25, RSMH_SORC5 ;
DR   Q1GRX1, RSMH_SPHAL ;  A5VDD4, RSMH_SPHWW ;  P60399, RSMH_SPIKU ;
DR   A7X1B8, RSMH_STAA1 ;  A6U0Z9, RSMH_STAA2 ;  Q2FHQ8, RSMH_STAA3 ;
DR   P60393, RSMH_STAA8 ;  A5IS65, RSMH_STAA9 ;  Q2YXE3, RSMH_STAAB ;
DR   Q5HGQ2, RSMH_STAAC ;  A6QG79, RSMH_STAAE ;  P60485, RSMH_STAAM ;
DR   P60392, RSMH_STAAN ;  Q6GHQ6, RSMH_STAAR ;  Q6GA33, RSMH_STAAS ;
DR   A8Z3M0, RSMH_STAAT ;  P60394, RSMH_STAAW ;  B9DPQ9, RSMH_STACT ;
DR   Q5HQ13, RSMH_STAEQ ;  Q8CSX7, RSMH_STAES ;  Q4L5N0, RSMH_STAHJ ;
DR   Q49WW1, RSMH_STAS1 ;  Q3K394, RSMH_STRA1 ;  Q8E782, RSMH_STRA3 ;
DR   Q8E1R8, RSMH_STRA5 ;  Q82AE4, RSMH_STRAW ;  Q9S2W4, RSMH_STRCO ;
DR   C5WIJ4, RSMH_STRDG ;  C0M7A8, RSMH_STRE4 ;  B4U4K4, RSMH_STREM ;
DR   A8AVS9, RSMH_STRGC ;  B1W0I2, RSMH_STRGG ;  B4SJW8, RSMH_STRM5 ;
DR   B2FNN0, RSMH_STRMK ;  Q8DVM7, RSMH_STRMU ;  P65431, RSMH_STRP1 ;
DR   Q04MC7, RSMH_STRP2 ;  P0DC36, RSMH_STRP3 ;  B5E6Z2, RSMH_STRP4 ;
DR   Q5XAL3, RSMH_STRP6 ;  C1CBB2, RSMH_STRP7 ;  P65433, RSMH_STRP8 ;
DR   Q1JAG5, RSMH_STRPB ;  Q1JKL7, RSMH_STRPC ;  Q1JFK8, RSMH_STRPD ;
DR   Q1J5F8, RSMH_STRPF ;  A2RD40, RSMH_STRPG ;  B1I953, RSMH_STRPI ;
DR   B8ZL51, RSMH_STRPJ ;  Q48RZ0, RSMH_STRPM ;  P0CB58, RSMH_STRPN ;
DR   P0DC37, RSMH_STRPQ ;  B2ISQ2, RSMH_STRPS ;  B5XML3, RSMH_STRPZ ;
DR   P59658, RSMH_STRR6 ;  A4W3H4, RSMH_STRS2 ;  C6GW75, RSMH_STRS4 ;
DR   C0MGV8, RSMH_STRS7 ;  C5VZR6, RSMH_STRSE ;  A3CPZ9, RSMH_STRSV ;
DR   C6GPU1, RSMH_STRSX ;  A4VX71, RSMH_STRSY ;  Q5LY91, RSMH_STRT1 ;
DR   Q5M2U6, RSMH_STRT2 ;  Q03J09, RSMH_STRTD ;  B9DV78, RSMH_STRU0 ;
DR   C1CCA8, RSMH_STRZJ ;  C1CIJ8, RSMH_STRZP ;  C1CPL0, RSMH_STRZT ;
DR   C1DTV7, RSMH_SULAA ;  Q30SF5, RSMH_SULDN ;  A8Z694, RSMH_SULMW ;
DR   A6Q7Y2, RSMH_SULNB ;  B2V5J5, RSMH_SULSY ;  Q67Q57, RSMH_SYMTH ;
DR   Q2LR39, RSMH_SYNAS ;  Q31PL4, RSMH_SYNE7 ;  A0LNY2, RSMH_SYNFM ;
DR   Q2JSF0, RSMH_SYNJA ;  Q2JLV1, RSMH_SYNJB ;  B1XP73, RSMH_SYNP2 ;
DR   Q5N4L0, RSMH_SYNP6 ;  A5GP74, RSMH_SYNPW ;  Q7U3X9, RSMH_SYNPX ;
DR   A5GWA2, RSMH_SYNR3 ;  Q0I6T7, RSMH_SYNS3 ;  Q3AW00, RSMH_SYNS9 ;
DR   Q3AGW9, RSMH_SYNSC ;  P73460, RSMH_SYNY3 ;  C5BP42, RSMH_TERTT ;
DR   B7IEL8, RSMH_THEAB ;  Q8DH87, RSMH_THEEB ;  Q47QX7, RSMH_THEFY ;
DR   A8F758, RSMH_THELT ;  A6LNR5, RSMH_THEM4 ;  Q9WZX6, RSMH_THEMA ;
DR   B9KA96, RSMH_THENN ;  A5IIR1, RSMH_THEP1 ;  B0K8J9, RSMH_THEP3 ;
DR   B0K3H8, RSMH_THEPX ;  B9L274, RSMH_THERP ;  B1LCF9, RSMH_THESQ ;
DR   P62476, RSMH_THET2 ;  Q5SJD8, RSMH_THET8 ;  Q8R9F9, RSMH_THETN ;
DR   B5YFU3, RSMH_THEYD ;  Q31I68, RSMH_THICR ;  Q3SMI1, RSMH_THIDA ;
DR   B8GMM1, RSMH_THISH ;  C4LA17, RSMH_TOLAT ;  P62477, RSMH_TREDE ;
DR   O83399, RSMH_TREPA ;  Q8KTR3, RSMH_TREPR ;  B2S2Y1, RSMH_TREPS ;
DR   Q10VG1, RSMH_TRIEI ;  Q83HJ6, RSMH_TROW8 ;  Q83GN7, RSMH_TROWT ;
DR   B1GZH8, RSMH_UNCTG ;  B1AJ25, RSMH_UREP2 ;  Q9PQA4, RSMH_UREPA ;
DR   B5ZBN2, RSMH_UREU1 ;  C5CNE6, RSMH_VARPS ;  A1WRK3, RSMH_VEREI ;
DR   A5CX97, RSMH_VESOH ;  Q9KPF9, RSMH_VIBCH ;  C3LQV4, RSMH_VIBCM ;
DR   Q5E2P2, RSMH_VIBF1 ;  B5FB43, RSMH_VIBFM ;  A7MWK7, RSMH_VIBHB ;
DR   Q9AJH1, RSMH_VIBPA ;  Q9AJG9, RSMH_VIBPR ;  B7VIZ5, RSMH_VIBSL ;
DR   Q8DEK2, RSMH_VIBVU ;  Q7MNV9, RSMH_VIBVY ;  Q8D2Y8, RSMH_WIGBR ;
DR   P62478, RSMH_WOLPM ;  B3CMB5, RSMH_WOLPP ;  Q7MSS6, RSMH_WOLSU ;
DR   Q5GTH5, RSMH_WOLTR ;  C0R598, RSMH_WOLWR ;  Q8PPB5, RSMH_XANAC ;
DR   Q3BXF9, RSMH_XANC5 ;  Q4UQW3, RSMH_XANC8 ;  B0RVB2, RSMH_XANCB ;
DR   Q8PCK7, RSMH_XANCP ;  Q2NZB1, RSMH_XANOM ;  B2SNY6, RSMH_XANOP ;
DR   Q5GW34, RSMH_XANOR ;  A7IGF4, RSMH_XANP2 ;  B2I9C0, RSMH_XYLF2 ;
DR   Q9PF88, RSMH_XYLFA ;  B0U504, RSMH_XYLFM ;  Q87AF2, RSMH_XYLFT ;
DR   A1JJI5, RSMH_YERE8 ;  A7FM74, RSMH_YERP3 ;  Q1C206, RSMH_YERPA ;
DR   B2K4D8, RSMH_YERPB ;  Q8ZIF7, RSMH_YERPE ;  A9R132, RSMH_YERPG ;
DR   Q1CMN5, RSMH_YERPN ;  A4TQ91, RSMH_YERPP ;  Q66EL3, RSMH_YERPS ;
DR   B1JK89, RSMH_YERPY ;  Q9REQ9, RSMH_ZYMMO ;
//
ID   2.1.1.200
DE   tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase.
AN   TrMet(Xm32).
CA   (1) S-adenosyl-L-methionine + cytidine(32) in tRNA = S-adenosyl-L-
CA   homocysteine + 2'-O-methylcytidine(32) in tRNA.
CA   (2) S-adenosyl-L-methionine + uridine(32) in tRNA = S-adenosyl-L-
CA   homocysteine + 2'-O-methyluridine(32) in tRNA.
CC   -!- In Escherichia coli TrmJ is the only methyltransferase responsible
CC       for the formation of 2'-O-methylcytidine(32) in tRNA.
CC   -!- No methylation of cytosine(34) in tRNA(Leu)(CAA).
CC   -!- In vitro the enzyme 2'-O-methylates cytidine(34) of tRNA(Ser1) and
CC       uridine(32) of tRNA(Gln2).
DR   A8AD50, TRMJ_CITK8 ;  Q8XA83, TRMJ_ECO57 ;  A1AE69, TRMJ_ECOK1 ;
DR   Q0TEV3, TRMJ_ECOL5 ;  P0AE02, TRMJ_ECOL6 ;  P0AE01, TRMJ_ECOLI ;
DR   Q1R8K0, TRMJ_ECOUT ;  A7MGX5, TRMJ_ENTS8 ;  Q6D257, TRMJ_ERWCT ;
DR   A6TCF3, TRMJ_KLEP7 ;  Q7N222, TRMJ_PHOLL ;  Q57LG7, TRMJ_SALCH ;
DR   Q5PNG3, TRMJ_SALPA ;  P66975, TRMJ_SALTI ;  P66974, TRMJ_SALTY ;
DR   Q31XV8, TRMJ_SHIBS ;  Q32D32, TRMJ_SHIDS ;  Q0T1Y7, TRMJ_SHIF8 ;
DR   P0AE03, TRMJ_SHIFL ;  Q3YZ20, TRMJ_SHISS ;  Q2NS29, TRMJ_SODGM ;
DR   A1JKQ0, TRMJ_YERE8 ;  Q1C5G8, TRMJ_YERPA ;  Q7CJN8, TRMJ_YERPE ;
DR   Q1CKB1, TRMJ_YERPN ;  A4TMV6, TRMJ_YERPP ;  Q667X9, TRMJ_YERPS ;
//
ID   2.1.1.201
DE   2-methoxy-6-polyprenyl-1,4-benzoquinol methylase.
CA   S-adenosyl-L-methionine + 2-methoxy-6-all-trans-polyprenyl-1,4-
CA   benzoquinol = S-adenosyl-L-homocysteine + 6-methoxy-3-methyl-2-all-trans-
CA   polyprenyl-1,4-benzoquinol.
CC   -!- This enzyme is involved in ubiquinone biosynthesis.
CC   -!- Ubiquinones from different organisms have a different number of
CC       prenyl units (for example, ubiquinone-6 in Saccharomyces, ubiquinone-
CC       9 in rat and ubiquinone-10 in human), and thus the natural substrate
CC       for the enzymes from different organisms has a different number of
CC       prenyl units.
CC   -!- However, the enzyme usually shows a low degree of specificity
CC       regarding the number of prenyl units.
CC   -!- For example, when the COQ5 gene from Saccharomyces cerevisiae is
CC       introduced into Escherichia coli, it complements the respiratory
CC       deficiency of an ubiE mutant.
CC   -!- The bifunctional enzyme from E.coli also catalyzes the methylation of
CC       demethylmenaquinol-8 (this activity is classified as EC 2.1.1.163).
PR   PROSITE; PDOC00911;
DR   Q9LVC8, COQ5_ARATH ;  Q0P5A2, COQ5_BOVIN ;  P34666, COQ5_CAEEL ;
DR   Q5ZLL5, COQ5_CHICK ;  Q66L51, COQ5_DANRE ;  Q54VN2, COQ5_DICDI ;
DR   Q9VYF8, COQ5_DROME ;  Q5HYK3, COQ5_HUMAN ;  Q9CXI0, COQ5_MOUSE ;
DR   Q5JNC0, COQ5_ORYSJ ;  Q5RBK6, COQ5_PONAB ;  Q4G064, COQ5_RAT   ;
DR   P87230, COQ5_SCHPO ;  Q4V7R3, COQ5_XENLA ;  P49017, COQ5_YEAST ;
DR   A5FZ96, UBIE_ACICJ ;  B9J7S8, UBIE_AGRRK ;  Q8UIH5, UBIE_AGRT5 ;
DR   B9JZF4, UBIE_AGRVS ;  C1DHS2, UBIE_AZOVD ;  A1UUE1, UBIE_BARBK ;
DR   Q6G577, UBIE_BARHE ;  Q6G1I2, UBIE_BARQU ;  A9ILA7, UBIE_BART1 ;
DR   Q6MHQ3, UBIE_BDEBA ;  Q7VRJ1, UBIE_BLOFL ;  Q491V7, UBIE_BLOPB ;
DR   Q2KUG1, UBIE_BORA1 ;  Q7WF12, UBIE_BORBR ;  Q7W3N6, UBIE_BORPA ;
DR   Q7W0H1, UBIE_BORPE ;  Q89WD0, UBIE_BRAJA ;  A5E888, UBIE_BRASB ;
DR   A4YJH0, UBIE_BRASO ;  B2SC50, UBIE_BRUA1 ;  Q2YJM4, UBIE_BRUA2 ;
DR   Q576Q0, UBIE_BRUAB ;  A9MCZ2, UBIE_BRUC2 ;  C0RMK3, UBIE_BRUMB ;
DR   Q8YDE4, UBIE_BRUME ;  A9WW74, UBIE_BRUSI ;  Q8FUZ3, UBIE_BRUSU ;
DR   B1YWF9, UBIE_BURA4 ;  Q1BTN4, UBIE_BURCA ;  B1JYJ6, UBIE_BURCC ;
DR   A0KAF5, UBIE_BURCH ;  B4EBC4, UBIE_BURCJ ;  Q0BBY4, UBIE_BURCM ;
DR   A9AFC0, UBIE_BURM1 ;  A3MNT8, UBIE_BURM7 ;  A2S8L1, UBIE_BURM9 ;
DR   Q62MP4, UBIE_BURMA ;  A1V753, UBIE_BURMS ;  A3NRJ4, UBIE_BURP0 ;
DR   Q3JVZ6, UBIE_BURP1 ;  A3N5U8, UBIE_BURP6 ;  B2JCU8, UBIE_BURP8 ;
DR   B2SX35, UBIE_BURPP ;  Q63XA0, UBIE_BURPS ;  Q39D13, UBIE_BURS3 ;
DR   Q2T139, UBIE_BURTA ;  A4JHS6, UBIE_BURVG ;  Q145P0, UBIE_BURXL ;
DR   A8FKB3, UBIE_CAMJ8 ;  Q9PIH5, UBIE_CAMJE ;  A1VY43, UBIE_CAMJJ ;
DR   Q5HWE7, UBIE_CAMJR ;  B8GVY5, UBIE_CAUCN ;  Q9A258, UBIE_CAUCR ;
DR   B0T7D0, UBIE_CAUSK ;  B3PH48, UBIE_CELJU ;  Q7NZD3, UBIE_CHRVO ;
DR   A8ACY2, UBIE_CITK8 ;  B6J676, UBIE_COXB1 ;  B6J3P6, UBIE_COXB2 ;
DR   A9KD75, UBIE_COXBN ;  A9N9F4, UBIE_COXBR ;  Q83A90, UBIE_COXBU ;
DR   Q0KEH6, UBIE_CUPNH ;  Q475X0, UBIE_CUPPJ ;  B2AH07, UBIE_CUPTR ;
DR   Q6ANL3, UBIE_DESPS ;  A8LNK7, UBIE_DINSH ;  A7ZU40, UBIE_ECO24 ;
DR   B7UNG3, UBIE_ECO27 ;  B7MHC0, UBIE_ECO45 ;  B7L996, UBIE_ECO55 ;
DR   P0A888, UBIE_ECO57 ;  B5YY82, UBIE_ECO5E ;  B7NV33, UBIE_ECO7I ;
DR   B7N2E1, UBIE_ECO81 ;  B7M638, UBIE_ECO8A ;  C5A009, UBIE_ECOBW ;
DR   B1XAJ7, UBIE_ECODH ;  A8A6U0, UBIE_ECOHS ;  A1AI22, UBIE_ECOK1 ;
DR   Q0TAM1, UBIE_ECOL5 ;  Q8FBJ0, UBIE_ECOL6 ;  B1IW72, UBIE_ECOLC ;
DR   P0A887, UBIE_ECOLI ;  B7NFD6, UBIE_ECOLU ;  B6I4H5, UBIE_ECOSE ;
DR   B1LM21, UBIE_ECOSM ;  Q1R477, UBIE_ECOUT ;  C5BCA4, UBIE_EDWI9 ;
DR   A4WFY5, UBIE_ENT38 ;  A7MQL7, UBIE_ENTS8 ;  Q6DAQ7, UBIE_ERWCT ;
DR   B2VG41, UBIE_ERWT9 ;  B7LU01, UBIE_ESCF3 ;  B0TZP1, UBIE_FRAP2 ;
DR   Q14GU4, UBIE_FRAT1 ;  A7NAA1, UBIE_FRATF ;  Q2A524, UBIE_FRATH ;
DR   B2SFA2, UBIE_FRATM ;  A0Q549, UBIE_FRATN ;  Q0BNE2, UBIE_FRATO ;
DR   Q5NFE1, UBIE_FRATT ;  A4IXH9, UBIE_FRATW ;  B5EFL1, UBIE_GEOBB ;
DR   B9LZA9, UBIE_GEOSF ;  Q74EU2, UBIE_GEOSL ;  C6E4U6, UBIE_GEOSM ;
DR   A5GA37, UBIE_GEOUR ;  P59911, UBIE_HAEDU ;  Q2SN12, UBIE_HAHCH ;
DR   Q5QYG2, UBIE_IDILO ;  B5XYI1, UBIE_KLEP3 ;  A6TGL3, UBIE_KLEP7 ;
DR   C1DCV3, UBIE_LARHH ;  Q5X0X6, UBIE_LEGPA ;  A5II90, UBIE_LEGPC ;
DR   Q5ZRH9, UBIE_LEGPH ;  Q5WSQ8, UBIE_LEGPL ;  A6VTA1, UBIE_MARMS ;
DR   Q606J9, UBIE_METCA ;  B8IJ00, UBIE_METNO ;  Q5F9R9, UBIE_NEIG1 ;
DR   B4RK11, UBIE_NEIG2 ;  A9M3A0, UBIE_NEIM0 ;  Q9JV83, UBIE_NEIMA ;
DR   Q9K075, UBIE_NEIMB ;  A1KT06, UBIE_NEIMF ;  Q81ZZ8, UBIE_NITEU ;
DR   Q1QS47, UBIE_NITHX ;  Q2Y6R0, UBIE_NITMU ;  A6WYI0, UBIE_OCHA4 ;
DR   A1BAN1, UBIE_PARDP ;  Q9CKD6, UBIE_PASMU ;  C6DI77, UBIE_PECCP ;
DR   Q3A209, UBIE_PELCD ;  B4RC42, UBIE_PHEZH ;  Q7MZ81, UBIE_PHOLL ;
DR   B4EWC9, UBIE_PROMH ;  Q48PJ4, UBIE_PSE14 ;  A6VDI6, UBIE_PSEA7 ;
DR   B7V3F6, UBIE_PSEA8 ;  Q02EV4, UBIE_PSEAB ;  Q9HUC0, UBIE_PSEAE ;
DR   Q1I3T0, UBIE_PSEE4 ;  C3K8U4, UBIE_PSEFS ;  Q3IJV7, UBIE_PSEHT ;
DR   A4XPM7, UBIE_PSEMY ;  Q9Z5E9, UBIE_PSEOL ;  A5WA45, UBIE_PSEP1 ;
DR   Q3KJC5, UBIE_PSEPF ;  B0KM36, UBIE_PSEPG ;  Q88D17, UBIE_PSEPK ;
DR   Q9Z439, UBIE_PSEPU ;  B1J2S8, UBIE_PSEPW ;  Q87UZ2, UBIE_PSESM ;
DR   Q4ZZG3, UBIE_PSEU2 ;  A4VGE5, UBIE_PSEU5 ;  A1SRS4, UBIE_PSYIN ;
DR   Q1LRG9, UBIE_RALME ;  B2UFG8, UBIE_RALPJ ;  Q8Y278, UBIE_RALSO ;
DR   B3PZ92, UBIE_RHIE6 ;  Q2KDB0, UBIE_RHIEC ;  Q1MME0, UBIE_RHIL3 ;
DR   Q98GV1, UBIE_RHILO ;  B5ZYK8, UBIE_RHILW ;  Q92SK7, UBIE_RHIME ;
DR   C3MCY6, UBIE_RHISN ;  Q2J2H9, UBIE_RHOP2 ;  Q6NDM2, UBIE_RHOPA ;
DR   Q13EN8, UBIE_RHOPS ;  B3Q619, UBIE_RHOPT ;  A3PFL1, UBIE_RHOS1 ;
DR   Q3IY65, UBIE_RHOS4 ;  A4WVR7, UBIE_RHOS5 ;  B9KQJ8, UBIE_RHOSK ;
DR   C3PLF4, UBIE_RICAE ;  A8GPI0, UBIE_RICAH ;  A8GXR2, UBIE_RICB8 ;
DR   Q1RJY5, UBIE_RICBR ;  A8EZP4, UBIE_RICCK ;  Q92GT5, UBIE_RICCN ;
DR   Q4UMW4, UBIE_RICFE ;  A8F2G9, UBIE_RICM5 ;  Q9ZCP3, UBIE_RICPR ;
DR   C4K2K3, UBIE_RICPU ;  B0BUT9, UBIE_RICRO ;  A8GT99, UBIE_RICRS ;
DR   Q68W57, UBIE_RICTY ;  Q16DL1, UBIE_ROSDO ;  Q9JPD1, UBIE_RUBGE ;
DR   Q21H69, UBIE_SACD2 ;  B5EZU8, UBIE_SALA4 ;  A9MIY3, UBIE_SALAR ;
DR   Q57HN8, UBIE_SALCH ;  B5FNW6, UBIE_SALDC ;  B5QW73, UBIE_SALEP ;
DR   B5RFM8, UBIE_SALG2 ;  B4TBR3, UBIE_SALHS ;  B4SZ73, UBIE_SALNS ;
DR   Q5PKP4, UBIE_SALPA ;  A9MY97, UBIE_SALPB ;  C0Q3E1, UBIE_SALPC ;
DR   B5BIX9, UBIE_SALPK ;  B4TNX9, UBIE_SALSV ;  P0A2K6, UBIE_SALTI ;
DR   P0A2K5, UBIE_SALTY ;  A8G8B8, UBIE_SERP5 ;  A1SAJ8, UBIE_SHEAM ;
DR   B8E6B6, UBIE_SHEB2 ;  A3D9F2, UBIE_SHEB5 ;  A6WIE9, UBIE_SHEB8 ;
DR   A9KYL8, UBIE_SHEB9 ;  Q12S23, UBIE_SHEDO ;  Q088H8, UBIE_SHEFN ;
DR   B0TJ16, UBIE_SHEHH ;  A3QIE1, UBIE_SHELP ;  Q8E9R7, UBIE_SHEON ;
DR   A8H966, UBIE_SHEPA ;  A4Y2Q5, UBIE_SHEPC ;  B8CI06, UBIE_SHEPW ;
DR   A0L1M4, UBIE_SHESA ;  A8G0S7, UBIE_SHESH ;  Q0HEA1, UBIE_SHESM ;
DR   Q0HZP7, UBIE_SHESR ;  A1RP78, UBIE_SHESW ;  B1KR07, UBIE_SHEWM ;
DR   B2TVI4, UBIE_SHIB3 ;  Q31UF3, UBIE_SHIBS ;  Q32A11, UBIE_SHIDS ;
DR   Q0SZ25, UBIE_SHIF8 ;  P0A889, UBIE_SHIFL ;  Q3YVD2, UBIE_SHISS ;
DR   Q1GC56, UBIE_SILST ;  A6UFF7, UBIE_SINMW ;  B4SJ34, UBIE_STRM5 ;
DR   B2FUU6, UBIE_STRMK ;  C5BRL2, UBIE_TERTT ;  Q31IM5, UBIE_THICR ;
DR   Q3SM81, UBIE_THIDA ;  A5F4E5, UBIE_VIBC3 ;  Q9KVQ6, UBIE_VIBCH ;
DR   C3LPS5, UBIE_VIBCM ;  A7MTX1, UBIE_VIBHB ;  Q87TH4, UBIE_VIBPA ;
DR   Q8DDP9, UBIE_VIBVU ;  Q7MQ33, UBIE_VIBVY ;  Q8D382, UBIE_WIGBR ;
DR   Q73HZ4, UBIE_WOLPM ;  C0R2Q3, UBIE_WOLWR ;  Q8PPP2, UBIE_XANAC ;
DR   Q8P558, UBIE_XANCP ;  Q2NYW4, UBIE_XANOM ;  B2IA21, UBIE_XYLF2 ;
DR   Q9PD92, UBIE_XYLFA ;  B0U6V1, UBIE_XYLFM ;  Q87DI1, UBIE_XYLFT ;
DR   A1JIF2, UBIE_YERE8 ;  A7FDE0, UBIE_YERP3 ;  Q1CBG0, UBIE_YERPA ;
DR   B2K0Y4, UBIE_YERPB ;  Q8D1I3, UBIE_YERPE ;  A9R431, UBIE_YERPG ;
DR   Q1CNB4, UBIE_YERPN ;  A4TR39, UBIE_YERPP ;  Q66FT0, UBIE_YERPS ;
DR   B1JP75, UBIE_YERPY ;  Q9X3X2, UBIE_ZYMMO ;
//
ID   2.1.1.202
DE   Multisite-specific tRNA:(cytosine-C(5))-methyltransferase.
CA   (1) S-adenosyl-L-methionine + cytosine(34) in tRNA precursor =
CA   S-adenosyl-L-homocysteine + 5-methylcytosine(34) in tRNA precursor.
CA   (2) S-adenosyl-L-methionine + cytosine(40) in tRNA precursor =
CA   S-adenosyl-L-homocysteine + 5-methylcytosine(40) in tRNA precursor.
CA   (3) S-adenosyl-L-methionine + cytosine(48) in tRNA precursor =
CA   S-adenosyl-L-homocysteine + 5-methylcytosine(48) in tRNA precursor.
CA   (4) S-adenosyl-L-methionine + cytosine(49) in tRNA precursor =
CA   S-adenosyl-L-homocysteine + 5-methylcytosine(49) in tRNA precursor.
CC   -!- The enzyme from Saccharomyces cerevisiae is responsible for complete
CC       5-methylcytosine methylations of yeast tRNA.
CC   -!- The incidence of modification depends on the cytosine position in
CC       tRNA.
CC   -!- At positions 34 and 40, 5-methylcytosine is found only in two yeast
CC       tRNAs (tRNA(Leu)(CUA) and tRNA(Phe)(GAA), respectively), whereas most
CC       other elongator yeast tRNAs bear either 5-methylcytosine(48) or
CC       5-methylcytosine(49), but never both in the same tRNA molecule.
CC   -!- The formation of 5-methylcytosine(34) and 5-methylcytosine(40) is a
CC       strictly intron-dependent process, whereas the formation of
CC       5-methylcytosine(48) and 5-methylcytosine(49) is an intron-
CC       independent process.
CC   -!- Formerly EC 2.1.1.29.
DR   Q9HGQ2, NCL1_SCHPO ;  P38205, NCL1_YEAST ;
//
ID   2.1.1.203
DE   tRNA (cytosine(34)-C(5))-methyltransferase.
CA   S-adenosyl-L-methionine + cytosine(34) in tRNA precursor = S-adenosyl-L-
CA   homocysteine + 5-methylcytosine(34) in tRNA precursor.
CC   -!- The human enzyme is specific for C(5)-methylation of cytosine(34) in
CC       tRNA precursors.
CC   -!- The intron in the human pre-tRNA(Leu)(CAA) is indispensable for the
CC       C(5)-methylation of cytosine in the first position of the anticodon.
CC   -!- It is not able to form 5-methylcytosine at positions 48 and 49 of
CC       human and yeast tRNA precursors.
CC   -!- Formerly EC 2.1.1.29.
DR   Q5ZLV4, NSUN2_CHICK;  Q9W4M9, NSUN2_DROME;  Q08J23, NSUN2_HUMAN;
DR   Q1HFZ0, NSUN2_MOUSE;  Q4V7N2, NSUN2_XENLA;  Q28E61, NSUN2_XENTR;
//
ID   2.1.1.204
DE   tRNA (cytosine(38)-C(5))-methyltransferase.
CA   S-adenosyl-L-methionine + cytosine(38) in tRNA = S-adenosyl-L-
CA   homocysteine + 5-methylcytosine(38) in tRNA.
CC   -!- The eukaryotic enzyme catalyzes methylation of cytosine(38) in the
CC       anti-codon loop of tRNA(Asp)(GTC), tRNA(Val)(AAC) and tRNA(Gly)(GCC).
CC   -!- Methylation by Dnmt2 protects tRNAs against stress-induced cleavage
CC       by ribonuclease.
CC   -!- Formerly EC 2.1.1.29.
PR   PROSITE; PDOC00089;
DR   Q7YS61, TRDMT_BOVIN;  O14717, TRDMT_HUMAN;  O55055, TRDMT_MOUSE;
DR   Q4G073, TRDMT_RAT  ;
//
ID   2.1.1.205
DE   tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase.
CA   S-adenosyl-L-methionine + cytidine(32)/guanosine(34) in tRNA =
CA   S-adenosyl-L-homocysteine + 2'-O-methylcytidine(32)/2'-O-
CA   methylguanosine(34) in tRNA.
CC   -!- The enzyme from Saccharomyces cerevisiae catalyzes the formation of
CC       2'-O-methylnucleotides at positions 32 and 34 of the yeast tRNA(Phe),
CC       tRNA(Trp) and, possibly, tRNA(Leu).
//
ID   2.1.1.206
DE   tRNA (cytidine(56)-2'-O)-methyltransferase.
CA   S-adenosyl-L-methionine + cytidine(56) in tRNA = S-adenosyl-L-
CA   homocysteine + 2'-O-methylcytidine(56) in tRNA.
CC   -!- The archaeal enzyme specifically catalyzes the S-adenosyl-L-
CC       methionine dependent 2'-O-ribose methylation of cytidine at position
CC       56 in tRNA transcripts.
DR   Q9YAD3, TRM56_AERPE;  O29507, TRM56_ARCFU;  A0RYD1, TRM56_CENSY;
DR   Q5V3R4, TRM56_HALMA;  B0R434, TRM56_HALS3;  Q9HRC8, TRM56_HALSA;
DR   Q18HD7, TRM56_HALWD;  A2BLW3, TRM56_HYPBU;  A8ABJ8, TRM56_IGNH4;
DR   A6UWW4, TRM56_META3;  Q8TL02, TRM56_METAC;  A7I7T4, TRM56_METB6;
DR   Q466X1, TRM56_METBF;  Q12Z63, TRM56_METBU;  Q2FT21, TRM56_METHJ;
DR   Q58780, TRM56_METJA;  Q8TX72, TRM56_METKA;  A2SQM4, TRM56_METLZ;
DR   A4FW99, TRM56_METM5;  A9A9N8, TRM56_METM6;  A6VH11, TRM56_METM7;
DR   Q8Q0Q0, TRM56_METMA;  A3CVQ1, TRM56_METMJ;  Q6LXC7, TRM56_METMP;
DR   A5ULQ9, TRM56_METS3;  A4YJ14, TRM56_METS5;  Q2NF55, TRM56_METST;
DR   O27185, TRM56_METTH;  A0B9Q9, TRM56_METTP;  A6UQ70, TRM56_METVS;
DR   Q3IP06, TRM56_NATPD;  A9A624, TRM56_NITMS;  Q6L171, TRM56_PICTO;
DR   Q9UYD1, TRM56_PYRAB;  Q8U3K5, TRM56_PYRFU;  O58214, TRM56_PYRHO;
DR   Q5JEG5, TRM56_PYRKO;  A3DN06, TRM56_STAMF;  Q877H6, TRM56_SULAC;
DR   Q980M4, TRM56_SULSO;  Q975T9, TRM56_SULTO;  Q9HJN6, TRM56_THEAC;
DR   A1RY31, TRM56_THEPD;  Q979R3, TRM56_THEVO;  Q0W8P0, TRM56_UNCMA;
//
ID   2.1.1.207
DE   tRNA (cytidine(34)-2'-O)-methyltransferase.
AN   tRNA (cytidine(34)/5-carboxymethylaminomethyluridine(34)-2'-O)-
AN   methyltransferase.
AN   tRNA methyltransferase L.
CA   (1) S-adenosyl-L-methionine + cytidine(34) in tRNA = S-adenosyl-L-
CA   homocysteine + 2'-O-methylcytidine(34) in tRNA.
CA   (2) S-adenosyl-L-methionine + 5-carboxymethylaminomethyluridine(34) in
CA   tRNA(Leu) = S-adenosyl-L-homocysteine + 5-carboxymethylaminomethyl-2'-O-
CA   methyluridine(34) in tRNA(Leu).
CC   -!- The enzyme from Escherichia coli catalyzes the 2'-O-methylation of
CC       cytidine or 5-carboxymethylaminomethyluridine at the wobble position
CC       at nucleotide 34 in tRNA(Leu)CmAA and tRNA(Leu)cmnm(5)UmAA.
CC   -!- The enzyme is selective for the two tRNA(Leu) isoacceptors and only
CC       methylates these when they present the correct anticodon loop
CC       sequence and modification pattern.
CC   -!- Specifically, YibK requires a pyrimidine nucleoside at position 34,
CC       it has a clear preference for an adenosine at position 35, and it
CC       fails to methylate without prior addition of the N(6)-(isopentenyl)-
CC       2-methylthioadenosine modification at position 37.
DR   A1WBM9, TRML_ACISJ ;  A0KEQ6, TRML_AERHH ;  O31590, TRML_BACSU ;
DR   B2IBT9, TRML_BEII9 ;  A0KAS4, TRML_BURCH ;  Q0BBL1, TRML_BURCM ;
DR   A3NR15, TRML_BURP0 ;  P0AGJ8, TRML_ECOL6 ;  P0AGJ7, TRML_ECOLI ;
DR   P32813, TRML_GEOSE ;  P44868, TRML_HAEIN ;  Q042B4, TRML_LACGA ;
DR   A2RKW7, TRML_LACLM ;  P69001, TRML_LISIN ;  Q721N0, TRML_LISMF ;
DR   C6X9I5, TRML_METSD ;  P47588, TRML_MYCGE ;  P75257, TRML_MYCPN ;
DR   C7BSD3, TRML_PHOAA ;  Q12E50, TRML_POLSJ ;  Q21LN7, TRML_SACD2 ;
DR   B8CHC9, TRML_SHEPW ;  D7A3L6, TRML_STAND ;  Q48V41, TRML_STRPM ;
DR   P74516, TRML_SYNY3 ;  Q74Y93, TRML_YERPE ;
//
ID   2.1.1.n1
DE   Resorcinol O-methyltransferase.
AN   O-methyltransferase 12.
CA   S-adenosyl-L-methionine + resorcinol = S-adenosyl-L-homocysteine +
CA   3-methoxy phenol.
CC   -!- The enzyme from Dictyostelium discoideum is involed in modifying the
CC       resorcinolic back-bone of the differentiation regulating factor
CC       4-methyl-5-pentylbenzene-1,3-diol.
CC   -!- It also shows activity toward 5-pentylbenzene-1,3-diol.
//
ID   2.1.1.n2
DE   tRNA (uridine(44)-2'-O-)-methyltransferase.
CA   S-adenosyl-L-methionine + uridine(44) in tRNA = S-adenosyl-L-homocysteine
CA   + 2'-O-methyluridine(44) in tRNA.
CC   -!- The enzyme catalyzes the 2'-O-methylation of U(44) in tRNA which is
CC       highly conserved in eukaryotes.
CC   -!- The enzyme is conserved among metazoans and fungi but is not found in
CC       plants.
DR   Q751E7, TRM44_ASHGO;  Q4WCV5, TRM44_ASPFU;  Q2U6Q1, TRM44_ASPOR;
DR   Q60K16, TRM44_CAEBR;  Q45EK7, TRM44_CAEEL;  Q6FKD6, TRM44_CANGA;
DR   Q6BRY1, TRM44_DEBHA;  Q9VHB9, TRM44_DROME;  Q5ASK9, TRM44_EMENI;
DR   Q4I1M9, TRM44_GIBZE;  Q8IYL2, TRM44_HUMAN;  Q6CR42, TRM44_KLULA;
DR   Q9D2Q2, TRM44_MOUSE;  Q7SE80, TRM44_NEUCR;  O74516, TRM44_SCHPO;
DR   Q4KLT3, TRM44_XENLA;  Q6C7U7, TRM44_YARLI;  Q02648, TRM44_YEAST;
//
ID   2.1.1.n3
DE   Selenocysteine Se-methyltransferase.
CA   S-methyl-L-methionine + L-selenocysteine = L-methionine + Se-methyl-L-
CA   selenocysteine.
DR   P56707, SMTA_ASTBI ;  Q4VNK0, SMTA_BRAOT ;
//
ID   2.1.1.n4
DE   Thiocyanate methyltransferase.
CA   S-adenosyl-L-methionine + thiocyanate = S-adenosyl-L-homocysteine +
CA   methyl thiocyanate.
DR   Q0WP12, HOL1_ARATH ;  Q93V78, TMT1_BRAOL ;  Q93XC4, TMT2_BRAOL ;
//
ID   2.1.1.n5
DE   N-terminal protein methyltransferase.
CA   (1) S-adenosyl-L-methionine + N-terminal-XPK-[protein] = S-adenosyl-L-
CA   homocysteine + methyl-N-XPK-[protein].
CA   (2) S-adenosyl-L-methionine + methyl-N-XPK-[protein] = S-adenosyl-L-
CA   homocysteine + dimethyl-N-XPK-[protein].
CA   (3) S-adenosyl-L-methionine + dimethyl-N-YPK-serine-[protein] =
CA   S-adenosyl-L-homocysteine + trimethyl-N-YPK-[protein].
CC   -!- X=alanine, serine or proline.
CC   -!- Y=alanine or serine.
CC   -!- The enzyme specifically catalyzes mono- or di- methylation (Ala,
CC       Ser or Pro) or tri-methylation (Ala or Ser) of the exposed alpha-
CC       amino group in the (Ala/Pro/Ser)-Pro-Lys motif.
CC   -!- The protein from Saccharomyces cerevisiae shows the highest activity
CC       toward the Pro-Pro-Lys-motif.
CC   -!- The Pro-Lys in positions 2-3 cannot be exchanged for other amino
CC       acids.
DR   Q4KL94, NT1AA_XENLA;  Q4KLE6, NT1AB_XENLA;  D2H163, NTM1A_AILME;
DR   Q2T9N3, NTM1A_BOVIN;  Q6NWX7, NTM1A_DANRE;  Q9BV86, NTM1A_HUMAN;
DR   Q8R2U4, NTM1A_MOUSE;  Q5BJX0, NTM1A_RAT  ;  B1H2P7, NTM1A_XENTR;
DR   B8JM82, NTM1B_DANRE;  Q5VVY1, NTM1B_HUMAN;  B2RXM4, NTM1B_MOUSE;
DR   D3ZVR1, NTM1B_RAT  ;  Q5PP70, NTM1_ARATH ;  A8WVR2, NTM1_CAEBR ;
DR   Q9N4D9, NTM1_CAEEL ;  Q55DH6, NTM1_DICDI ;  Q6NN40, NTM1_DROME ;
DR   A2XMJ1, NTM1_ORYSI ;  Q10CT5, NTM1_ORYSJ ;  O13748, NTM1_SCHPO ;
DR   P38340, NTM1_YEAST ;
//
ID   2.1.1.n6
DE   Geranyl diphosphate 2-C-methyltransferase.
AN   GPP methyltransferase.
CA   S-adenosyl-L-methionine + geranyl diphosphate = S-adenosyl-L-homocysteine
CA   + (E)-2-methylgeranyl diphosphate.
CF   Magnesium.
CC   -!- The enzyme from Streptomyces coelicolor is involved in the
CC       biosynthesis of the earthy odorant methylisoborneol.
DR   A4FG18, GPPMT_SACEN;  A3KI18, GPPMT_STRAM;  Q9F1Y5, GPPMT_STRCO;
DR   D3KYU3, GPPMT_STRLS;
//
ID   2.1.1.n7
DE   5-pentadecatrienyl resorcinol O-methyltransferase.
CA   S-adenosyl-L-methionine + (8Z,11Z)-5-(pentadeca-8,11,14-trien-1-
CA   yl)resorcinol = S-adenosyl-L-homocysteine + (8Z,11Z)-5-(pentadeca-
CA   8,11,14-trien-1-yl)resorcinol-3-methyl ether.
CC   -!- In Sorghum, this enzyme is part of the biosynthetic pathway of the
CC       phytotoxin sorgoleone.
DR   A8QW53, OMT3_SORBI ;
//
ID   2.1.2.1
DE   Glycine hydroxymethyltransferase.
AN   Serine aldolase.
AN   Serine hydroxymethylase.
AN   Serine hydroxymethyltransferase.
AN   Threonine aldolase.
CA   5,10-methylenetetrahydrofolate + glycine + H(2)O = tetrahydrofolate +
CA   L-serine.
CF   Pyridoxal 5'-phosphate.
CC   -!- Also catalyzes the reaction of glycine with acetaldehyde to form
CC       L-threonine, and with 4-trimethylammoniobutanal to form 3-hydroxy-
CC       N(6),N(6),N(6)-trimethyl-L-lysine.
PR   PROSITE; PDOC00090;
DR   Q8UG75, GLYA1_AGRT5;  Q7WPH6, GLYA1_BORBR;  Q7W1I6, GLYA1_BORPA;
DR   Q62I16, GLYA1_BURMA;  Q3JP81, GLYA1_BURP1;  Q63RB4, GLYA1_BURPS;
DR   Q39A26, GLYA1_BURS3;  Q2SYS4, GLYA1_BURTA;  Q488N6, GLYA1_COLP3;
DR   Q474L3, GLYA1_CUPPJ;  Q6D246, GLYA1_ERWCT;  Q2SFI7, GLYA1_HAHCH;
DR   P59953, GLYA1_MYCBO;  O53441, GLYA1_MYCTU;  Q6LU17, GLYA1_PHOPR;
DR   Q48DU7, GLYA1_PSE14;  Q9HTE9, GLYA1_PSEAE;  Q4K5R9, GLYA1_PSEF5;
DR   Q3KDV1, GLYA1_PSEPF;  Q88R12, GLYA1_PSEPK;  Q88AD1, GLYA1_PSESM;
DR   Q4ZNH2, GLYA1_PSEU2;  Q8Y1G1, GLYA1_RALSO;  Q983B6, GLYA1_RHILO;
DR   Q92QU6, GLYA1_RHIME;  Q6N693, GLYA1_RHOPA;  Q2RVA2, GLYA1_RHORT;
DR   Q30R29, GLYA1_SULDN;  Q9KTG1, GLYA1_VIBCH;  Q87RR2, GLYA1_VIBPA;
DR   Q8DFC9, GLYA1_VIBVU;  Q7MN19, GLYA1_VIBVY;  Q8U7Y5, GLYA2_AGRT5;
DR   Q7WFD2, GLYA2_BORBR;  Q7W400, GLYA2_BORPA;  Q62DI5, GLYA2_BURMA;
DR   Q3JGP5, GLYA2_BURP1;  Q63MV1, GLYA2_BURPS;  Q391K1, GLYA2_BURS3;
DR   Q2T437, GLYA2_BURTA;  Q481S6, GLYA2_COLP3;  Q46RR4, GLYA2_CUPPJ;
DR   Q6CZV5, GLYA2_ERWCT;  Q2S9R4, GLYA2_HAHCH;  Q7U2X3, GLYA2_MYCBO;
DR   O53615, GLYA2_MYCTU;  Q6LHN7, GLYA2_PHOPR;  Q48CP3, GLYA2_PSE14;
DR   Q9I138, GLYA2_PSEAE;  Q4K4P6, GLYA2_PSEF5;  Q3K6J0, GLYA2_PSEPF;
DR   Q88Q27, GLYA2_PSEPK;  Q87WC1, GLYA2_PSESM;  Q4ZM83, GLYA2_PSEU2;
DR   Q8XTQ1, GLYA2_RALSO;  Q98A81, GLYA2_RHILO;  Q92XS8, GLYA2_RHIME;
DR   Q6N622, GLYA2_RHOPA;  Q2RTB8, GLYA2_RHORT;  Q8Z2Z9, GLYA2_SALTI;
DR   Q30P60, GLYA2_SULDN;  Q9KMP4, GLYA2_VIBCH;  Q87I03, GLYA2_VIBPA;
DR   Q8D7G5, GLYA2_VIBVU;  Q7MEH7, GLYA2_VIBVY;  Q39J72, GLYA3_BURS3;
DR   Q47XG4, GLYA3_COLP3;  Q9HVI7, GLYA3_PSEAE;  Q3K5K9, GLYA3_PSEPF;
DR   Q47WY2, GLYA4_COLP3;  B0CEI9, GLYA_ACAM1 ;  A9NEA9, GLYA_ACHLI ;
DR   A1TRH1, GLYA_ACIAC ;  Q6FA66, GLYA_ACIAD ;  B7GZR6, GLYA_ACIB3 ;
DR   B7I2R7, GLYA_ACIB5 ;  B2HUY9, GLYA_ACIBC ;  Q1IS84, GLYA_ACIBL ;
DR   B0VLF5, GLYA_ACIBS ;  A3M736, GLYA_ACIBT ;  B0VBB3, GLYA_ACIBY ;
DR   A0LV49, GLYA_ACIC1 ;  C1F3Q7, GLYA_ACIC5 ;  A5G0E0, GLYA_ACICJ ;
DR   B9MAC8, GLYA_ACIET ;  B7J439, GLYA_ACIF2 ;  B5ELV3, GLYA_ACIF5 ;
DR   O85718, GLYA_ACIRA ;  A1W6H6, GLYA_ACISJ ;  A3MYT3, GLYA_ACTP2 ;
DR   B3H053, GLYA_ACTP7 ;  B0BSL4, GLYA_ACTPJ ;  A6VP23, GLYA_ACTSZ ;
DR   A0KNH4, GLYA_AERHH ;  Q9YAH7, GLYA_AERPE ;  A4SJN4, GLYA_AERS4 ;
DR   P34894, GLYA_AGGAC ;  B9JCX4, GLYA_AGRRK ;  B9JV74, GLYA_AGRVS ;
DR   Q0VMH4, GLYA_ALCBS ;  Q0ABQ9, GLYA_ALHEH ;  B6EHX0, GLYA_ALISL ;
DR   A6TQQ1, GLYA_ALKMQ ;  A8MGL7, GLYA_ALKOO ;  B4RV95, GLYA_ALTMD ;
DR   B3ER62, GLYA_AMOA5 ;  B8JEW9, GLYA_ANAD2 ;  Q2ILI1, GLYA_ANADE ;
DR   A7HDY8, GLYA_ANADF ;  B9KHP8, GLYA_ANAMF ;  Q5PBM8, GLYA_ANAMM ;
DR   Q2GLH3, GLYA_ANAPZ ;  B4UIM7, GLYA_ANASK ;  B9MR57, GLYA_ANATD ;
DR   Q3MBD8, GLYA_ANAVT ;  B7GMG4, GLYA_ANOFW ;  O66776, GLYA_AQUAE ;
DR   O29406, GLYA_ARCFU ;  Q5P7P1, GLYA_AROAE ;  Q2NIT8, GLYA_AYWBP ;
DR   B6YS43, GLYA_AZOPC ;  A1K9B2, GLYA_AZOSB ;  C1DEQ3, GLYA_AZOVD ;
DR   A7Z9Q9, GLYA_BACA2 ;  C3P1G5, GLYA_BACAA ;  C3LFJ0, GLYA_BACAC ;
DR   A0RLA3, GLYA_BACAH ;  Q81JY4, GLYA_BACAN ;  B7JGP1, GLYA_BACC0 ;
DR   Q72XD7, GLYA_BACC1 ;  B7IQW9, GLYA_BACC2 ;  C1F0N9, GLYA_BACC3 ;
DR   B7HFL3, GLYA_BACC4 ;  B7HY76, GLYA_BACC7 ;  A7GV66, GLYA_BACCN ;
DR   B9IRU8, GLYA_BACCQ ;  Q814V2, GLYA_BACCR ;  Q630T3, GLYA_BACCZ ;
DR   Q5LD58, GLYA_BACFN ;  Q64U78, GLYA_BACFR ;  Q9K6G4, GLYA_BACHD ;
DR   Q6HAW9, GLYA_BACHK ;  Q65DW5, GLYA_BACLD ;  A8FIC1, GLYA_BACP2 ;
DR   Q5WB66, GLYA_BACSK ;  P39148, GLYA_BACSU ;  Q8A9S7, GLYA_BACTN ;
DR   A6L5K3, GLYA_BACV8 ;  A9VSB4, GLYA_BACWK ;  A1USI0, GLYA_BARBK ;
DR   Q6G3L3, GLYA_BARHE ;  Q6G009, GLYA_BARQU ;  A9IVC5, GLYA_BART1 ;
DR   Q1LU81, GLYA_BAUCH ;  Q6MLK1, GLYA_BDEBA ;  B2IJJ3, GLYA_BEII9 ;
DR   A1A1V0, GLYA_BIFAA ;  B7GTL3, GLYA_BIFLS ;  Q7VRR4, GLYA_BLOFL ;
DR   Q492D5, GLYA_BLOPB ;  Q2KV15, GLYA_BORA1 ;  Q0SMQ5, GLYA_BORAP ;
DR   O51547, GLYA_BORBU ;  B7J2G3, GLYA_BORBZ ;  B5RMF3, GLYA_BORDL ;
DR   Q660S1, GLYA_BORGA ;  B2S0U9, GLYA_BORHD ;  A9I292, GLYA_BORPD ;
DR   Q7VUW7, GLYA_BORPE ;  B5RPU9, GLYA_BORRA ;  A1R032, GLYA_BORT9 ;
DR   P24060, GLYA_BRAJA ;  A5EKI3, GLYA_BRASB ;  A4YW97, GLYA_BRASO ;
DR   B2S513, GLYA_BRUA1 ;  Q2YN95, GLYA_BRUA2 ;  Q57DY5, GLYA_BRUAB ;
DR   A9MAE5, GLYA_BRUC2 ;  C0RIA2, GLYA_BRUMB ;  Q8YGG7, GLYA_BRUME ;
DR   A5VPU7, GLYA_BRUO2 ;  B0CL90, GLYA_BRUSI ;  Q8G1F1, GLYA_BRUSU ;
DR   B8D981, GLYA_BUCA5 ;  P57376, GLYA_BUCAI ;  Q8K9P2, GLYA_BUCAP ;
DR   P59432, GLYA_BUCBP ;  Q057P9, GLYA_BUCCC ;  A8MBA2, GLYA_CALMQ ;
DR   A4XL61, GLYA_CALS8 ;  A7ZFA4, GLYA_CAMC1 ;  A7GX48, GLYA_CAMC5 ;
DR   A0RQ16, GLYA_CAMFF ;  A7I3S9, GLYA_CAMHC ;  A8FKI9, GLYA_CAMJ8 ;
DR   A7H4X6, GLYA_CAMJD ;  P24531, GLYA_CAMJE ;  A1VYC2, GLYA_CAMJJ ;
DR   Q5HW65, GLYA_CAMJR ;  Q3A934, GLYA_CARHZ ;  Q9A8J6, GLYA_CAUCR ;
DR   B0T1I5, GLYA_CAUSK ;  B3PBD6, GLYA_CELJU ;  A0RYP2, GLYA_CENSY ;
DR   A9WI58, GLYA_CHLAA ;  Q5L6P4, GLYA_CHLAB ;  B8G933, GLYA_CHLAD ;
DR   Q3APN5, GLYA_CHLCH ;  Q824C8, GLYA_CHLCV ;  Q253I4, GLYA_CHLFF ;
DR   B3EFN5, GLYA_CHLL2 ;  Q9PJW0, GLYA_CHLMU ;  B3QPR3, GLYA_CHLP8 ;
DR   B3EMW0, GLYA_CHLPB ;  A1BE30, GLYA_CHLPD ;  Q9Z831, GLYA_CHLPN ;
DR   B9LKK8, GLYA_CHLSY ;  B0B804, GLYA_CHLT2 ;  B3QUG2, GLYA_CHLT3 ;
DR   Q3KLR8, GLYA_CHLTA ;  B0BC69, GLYA_CHLTB ;  Q8KC36, GLYA_CHLTE ;
DR   O84439, GLYA_CHLTR ;  Q1QU94, GLYA_CHRSD ;  Q7NYI8, GLYA_CHRVO ;
DR   A8AD38, GLYA_CITK8 ;  A5CU18, GLYA_CLAM3 ;  B0RDR3, GLYA_CLAMS ;
DR   Q97GV1, GLYA_CLOAB ;  A7FWM6, GLYA_CLOB1 ;  C3L181, GLYA_CLOB6 ;
DR   A6LUK9, GLYA_CLOB8 ;  B2V398, GLYA_CLOBA ;  B2TN52, GLYA_CLOBB ;
DR   A5I526, GLYA_CLOBH ;  C1FTF1, GLYA_CLOBJ ;  B1IJJ8, GLYA_CLOBK ;
DR   A7GGI2, GLYA_CLOBL ;  B1KXQ5, GLYA_CLOBM ;  B8I2N8, GLYA_CLOCE ;
DR   Q183G0, GLYA_CLOD6 ;  B9E156, GLYA_CLOK1 ;  A5N7P5, GLYA_CLOK5 ;
DR   A0PZX4, GLYA_CLONN ;  Q0TP32, GLYA_CLOP1 ;  Q8XJ32, GLYA_CLOPE ;
DR   A9KSH6, GLYA_CLOPH ;  Q0SRQ2, GLYA_CLOPS ;  A3DEB1, GLYA_CLOTH ;
DR   B5Y8G6, GLYA_COPPD ;  Q6NI47, GLYA_CORDI ;  Q8FQR1, GLYA_COREF ;
DR   A4QCW6, GLYA_CORGB ;  Q93PM7, GLYA_CORGL ;  Q4JU69, GLYA_CORJK ;
DR   P50434, GLYA_CORS1 ;  B1VFM5, GLYA_CORU7 ;  B6J8Q9, GLYA_COXB1 ;
DR   B6IZ80, GLYA_COXB2 ;  A9KBN4, GLYA_COXBN ;  A9N8T8, GLYA_COXBR ;
DR   Q83BT3, GLYA_COXBU ;  Q0K7W0, GLYA_CUPNH ;  B3R5S0, GLYA_CUPTR ;
DR   B1WPY4, GLYA_CYAA5 ;  B8HR59, GLYA_CYAP4 ;  B7KD38, GLYA_CYAP7 ;
DR   B7JYG9, GLYA_CYAP8 ;  Q11NZ7, GLYA_CYTH3 ;  Q47IH1, GLYA_DECAR ;
DR   Q3Z9B9, GLYA_DEHE1 ;  A5FS31, GLYA_DEHSB ;  Q3ZZG3, GLYA_DEHSC ;
DR   C1CYT8, GLYA_DEIDV ;  Q1J1W0, GLYA_DEIGD ;  Q9RYB2, GLYA_DEIRA ;
DR   B8FJ72, GLYA_DESAA ;  C0QKX3, GLYA_DESAH ;  B1I6M4, GLYA_DESAP ;
DR   B8J189, GLYA_DESDA ;  Q30YL7, GLYA_DESDG ;  B8FZ69, GLYA_DESHD ;
DR   Q24MM6, GLYA_DESHY ;  A8ZTV3, GLYA_DESOH ;  Q6AM21, GLYA_DESPS ;
DR   A4J9B1, GLYA_DESRM ;  Q72CT0, GLYA_DESVH ;  B8DJF7, GLYA_DESVM ;
DR   A1VEK5, GLYA_DESVV ;  A5EVR7, GLYA_DICNV ;  B5YDB7, GLYA_DICT6 ;
DR   B8E008, GLYA_DICTD ;  A7ZPZ4, GLYA_ECO24 ;  B7UGZ1, GLYA_ECO27 ;
DR   B7MIN5, GLYA_ECO45 ;  B7LDE3, GLYA_ECO55 ;  Q8XA55, GLYA_ECO57 ;
DR   B5Z123, GLYA_ECO5E ;  B7NRK2, GLYA_ECO7I ;  B7MYI0, GLYA_ECO81 ;
DR   B7M8A7, GLYA_ECO8A ;  C4ZXC6, GLYA_ECOBW ;  B1XB26, GLYA_ECODH ;
DR   A8A359, GLYA_ECOHS ;  A1AE82, GLYA_ECOK1 ;  Q0TET8, GLYA_ECOL5 ;
DR   P0A826, GLYA_ECOL6 ;  B1IVS6, GLYA_ECOLC ;  P0A825, GLYA_ECOLI ;
DR   B7N6D8, GLYA_ECOLU ;  B6I5C4, GLYA_ECOSE ;  B1LNK7, GLYA_ECOSM ;
DR   Q1R8I4, GLYA_ECOUT ;  C5BEV2, GLYA_EDWI9 ;  Q3YRD1, GLYA_EHRCJ ;
DR   Q2GHF1, GLYA_EHRCR ;  Q5FG30, GLYA_EHRRG ;  Q5HAJ7, GLYA_EHRRW ;
DR   B2KER5, GLYA_ELUMP ;  A4WDC0, GLYA_ENT38 ;  Q831F9, GLYA_ENTFA ;
DR   A7MGY5, GLYA_ENTS8 ;  B2VI25, GLYA_ERWT9 ;  Q2NAR9, GLYA_ERYLH ;
DR   C4ZH69, GLYA_EUBR3 ;  B1YEH3, GLYA_EXIS2 ;  A7HJ69, GLYA_FERNB ;
DR   B0S1N3, GLYA_FINM2 ;  A5FEF4, GLYA_FLAJ1 ;  A6GXG2, GLYA_FLAPJ ;
DR   B0TYH3, GLYA_FRAP2 ;  Q14GZ5, GLYA_FRAT1 ;  A7NB66, GLYA_FRATF ;
DR   Q2A498, GLYA_FRATH ;  B2SGE5, GLYA_FRATM ;  A0Q7C5, GLYA_FRATN ;
DR   Q0BMN1, GLYA_FRATO ;  Q5NFJ3, GLYA_FRATT ;  A4IXD7, GLYA_FRATW ;
DR   B5E8U0, GLYA_GEOBB ;  Q5KUI2, GLYA_GEOKA ;  B3E1Z8, GLYA_GEOLS ;
DR   Q39V87, GLYA_GEOMG ;  B9M0W5, GLYA_GEOSF ;  Q74CR5, GLYA_GEOSL ;
DR   C6E348, GLYA_GEOSM ;  A4ITJ9, GLYA_GEOTN ;  A5GF66, GLYA_GEOUR ;
DR   Q7ND67, GLYA_GLOVI ;  Q5FNK4, GLYA_GLUOX ;  Q0BTE6, GLYA_GRABC ;
DR   A0M3N2, GLYA_GRAFK ;  Q4QM19, GLYA_HAEI8 ;  A5UDI4, GLYA_HAEIE ;
DR   A5UI33, GLYA_HAEIG ;  P43844, GLYA_HAEIN ;  B8F407, GLYA_HAEPS ;
DR   Q0I555, GLYA_HAES1 ;  B0UWS8, GLYA_HAES2 ;  A1WVG6, GLYA_HALHL ;
DR   B9LQJ1, GLYA_HALLT ;  Q5V3D7, GLYA_HALMA ;  B8CYJ3, GLYA_HALOH ;
DR   B0R5J9, GLYA_HALS3 ;  Q9HPY5, GLYA_HALSA ;  Q18GK0, GLYA_HALWD ;
DR   Q17YS0, GLYA_HELAH ;  Q7VFL1, GLYA_HELHP ;  B0TI64, GLYA_HELMI ;
DR   B6JPT2, GLYA_HELP2 ;  B5Z9V7, GLYA_HELPG ;  Q1CUX5, GLYA_HELPH ;
DR   Q9ZMP7, GLYA_HELPJ ;  B2US14, GLYA_HELPS ;  P56089, GLYA_HELPY ;
DR   A9AYB7, GLYA_HERA2 ;  A4G7M4, GLYA_HERAR ;  B4U7S5, GLYA_HYDS0 ;
DR   A2BM73, GLYA_HYPBU ;  P34895, GLYA_HYPME ;  Q0C0I5, GLYA_HYPNA ;
DR   Q5QXT4, GLYA_IDILO ;  A6T0T6, GLYA_JANMA ;  Q28N04, GLYA_JANSC ;
DR   A6WF55, GLYA_KINRD ;  B5XNI6, GLYA_KLEP3 ;  A6TCG5, GLYA_KLEP7 ;
DR   B2GM31, GLYA_KOCRD ;  B1L5K9, GLYA_KORCO ;  C5CEA8, GLYA_KOSOT ;
DR   Q5FMC0, GLYA_LACAC ;  Q03QY0, GLYA_LACBA ;  Q03A26, GLYA_LACC3 ;
DR   B3WDL0, GLYA_LACCB ;  B2GAT4, GLYA_LACF3 ;  Q046F8, GLYA_LACGA ;
DR   Q74LC1, GLYA_LACJO ;  Q9CHW7, GLYA_LACLA ;  A2RIS0, GLYA_LACLM ;
DR   Q031D7, GLYA_LACLS ;  Q88UT5, GLYA_LACPL ;  A5VIP9, GLYA_LACRD ;
DR   B2G679, GLYA_LACRJ ;  Q1WTR3, GLYA_LACS1 ;  Q38WJ7, GLYA_LACSS ;
DR   Q1MS11, GLYA_LAWIP ;  Q5X722, GLYA_LEGPA ;  A5IGI2, GLYA_LEGPC ;
DR   Q5ZXK6, GLYA_LEGPH ;  Q5WYH4, GLYA_LEGPL ;  Q6ADF0, GLYA_LEIXX ;
DR   B0SEF8, GLYA_LEPBA ;  Q04R46, GLYA_LEPBJ ;  Q04ZF5, GLYA_LEPBL ;
DR   B0SMI6, GLYA_LEPBP ;  B1XYE7, GLYA_LEPCP ;  Q72PY2, GLYA_LEPIC ;
DR   Q8F6A0, GLYA_LEPIN ;  B1MYF5, GLYA_LEUCK ;  Q03Y25, GLYA_LEUMM ;
DR   Q927V4, GLYA_LISIN ;  C1KYV6, GLYA_LISMC ;  Q71WN9, GLYA_LISMF ;
DR   B8DBH0, GLYA_LISMH ;  Q8Y4B2, GLYA_LISMO ;  A0ALM4, GLYA_LISW6 ;
DR   B1HM45, GLYA_LYSSC ;  B9E8F5, GLYA_MACCJ ;  Q2W4T2, GLYA_MAGSA ;
DR   A0L403, GLYA_MAGSM ;  Q65T08, GLYA_MANSM ;  A1TYW8, GLYA_MARAV ;
DR   Q0APF8, GLYA_MARMM ;  A6VXM6, GLYA_MARMS ;  Q6F211, GLYA_MESFL ;
DR   A6UVV2, GLYA_META3 ;  Q8TK94, GLYA_METAC ;  Q46A52, GLYA_METBF ;
DR   B7KVA7, GLYA_METC4 ;  Q607U4, GLYA_METCA ;  P50435, GLYA_METEA ;
DR   A9VYW6, GLYA_METEP ;  Q1H003, GLYA_METFK ;  Q2FLH5, GLYA_METHJ ;
DR   Q58992, GLYA_METJA ;  Q8TZ19, GLYA_METKA ;  Q8PZQ0, GLYA_METMA ;
DR   B1ZJN1, GLYA_METPB ;  B8GG35, GLYA_METPE ;  B1LZ88, GLYA_METRJ ;
DR   A5UMW4, GLYA_METS3 ;  B0UML5, GLYA_METS4 ;  A4YHA3, GLYA_METS5 ;
DR   Q2NEA8, GLYA_METST ;  O27433, GLYA_METTH ;  P50436, GLYA_METTM ;
DR   A0B8J6, GLYA_METTP ;  B0JPX8, GLYA_MICAN ;  Q2RFW7, GLYA_MOOTA ;
DR   A0QC23, GLYA_MYCA1 ;  B3PN94, GLYA_MYCA5 ;  A5IXK9, GLYA_MYCAP ;
DR   Q2ST43, GLYA_MYCCT ;  Q7NBH8, GLYA_MYCGA ;  P47634, GLYA_MYCGE ;
DR   Q601P7, GLYA_MYCH2 ;  Q4A8E1, GLYA_MYCH7 ;  Q4AAB2, GLYA_MYCHJ ;
DR   B8ZSH2, GLYA_MYCLB ;  Q9X794, GLYA_MYCLE ;  Q6KHH3, GLYA_MYCMO ;
DR   Q6MS85, GLYA_MYCMS ;  Q73WG1, GLYA_MYCPA ;  Q8EWD1, GLYA_MYCPE ;
DR   P78011, GLYA_MYCPN ;  Q98QM2, GLYA_MYCPU ;  A0R2V7, GLYA_MYCS2 ;
DR   Q4A6A3, GLYA_MYCS5 ;  Q1D345, GLYA_MYXXD ;  Q3IRX5, GLYA_NATPD ;
DR   B2A3H6, GLYA_NATTJ ;  Q5F8C0, GLYA_NEIG1 ;  B4RLC9, GLYA_NEIG2 ;
DR   Q9XB01, GLYA_NEIGO ;  A9LYX4, GLYA_NEIM0 ;  Q9XAY7, GLYA_NEIMA ;
DR   P56990, GLYA_NEIMB ;  Q9XAZ1, GLYA_NEIMF ;  Q2GEI3, GLYA_NEOSM ;
DR   Q0AFT6, GLYA_NITEC ;  Q82UP9, GLYA_NITEU ;  Q1QMB9, GLYA_NITHX ;
DR   A9A3Y9, GLYA_NITMS ;  Q2YD58, GLYA_NITMU ;  Q3J9K8, GLYA_NITOC ;
DR   A6Q478, GLYA_NITSB ;  Q3SRV3, GLYA_NITWN ;  Q5YQ76, GLYA_NOCFA ;
DR   B2J2A2, GLYA_NOSP7 ;  Q8YMW8, GLYA_NOSS1 ;  Q2G646, GLYA_NOVAD ;
DR   Q8EM73, GLYA_OCEIH ;  A6X1Y9, GLYA_OCHA4 ;  Q04FR7, GLYA_OENOB ;
DR   B6JGH9, GLYA_OLICO ;  Q6YR37, GLYA_ONYPE ;  B1ZZW8, GLYA_OPITP ;
DR   A5CCC4, GLYA_ORITB ;  B3CTZ1, GLYA_ORITI ;  A6LBG7, GLYA_PARD8 ;
DR   A1B0I7, GLYA_PARDP ;  P57830, GLYA_PASMU ;  Q03EK4, GLYA_PEDPA ;
DR   Q3A4L9, GLYA_PELCD ;  Q3B2I7, GLYA_PELLD ;  B4SE31, GLYA_PELPB ;
DR   A1APU0, GLYA_PELPD ;  A5CYB7, GLYA_PELTS ;  Q4FLT4, GLYA_PELUB ;
DR   C0QQE4, GLYA_PERMH ;  A9BIK8, GLYA_PETMO ;  B4RB35, GLYA_PHEZH ;
DR   Q7N216, GLYA_PHOLL ;  B1V975, GLYA_PHYAS ;  B3R0G5, GLYA_PHYMT ;
DR   Q6L1F6, GLYA_PICTO ;  A1VRC8, GLYA_POLNA ;  B1XTC3, GLYA_POLNS ;
DR   Q129K3, GLYA_POLSJ ;  A4SVI6, GLYA_POLSQ ;  B2RGR2, GLYA_PORG3 ;
DR   Q7MXW0, GLYA_PORGI ;  B4S5Y9, GLYA_PROA2 ;  Q6AAU3, GLYA_PROAC ;
DR   A3PAX9, GLYA_PROM0 ;  A2C090, GLYA_PROM1 ;  A8G2R8, GLYA_PROM2 ;
DR   A2CCJ3, GLYA_PROM3 ;  A9BDM9, GLYA_PROM4 ;  A2BUN9, GLYA_PROM5 ;
DR   Q31CS4, GLYA_PROM9 ;  Q7VDS8, GLYA_PROMA ;  B4EZV5, GLYA_PROMH ;
DR   Q7V4U3, GLYA_PROMM ;  Q7V335, GLYA_PROMP ;  A2BP57, GLYA_PROMS ;
DR   Q46HB6, GLYA_PROMT ;  A4SFY3, GLYA_PROVI ;  Q15WB3, GLYA_PSEA6 ;
DR   Q3II23, GLYA_PSEHT ;  A4VI36, GLYA_PSEU5 ;  Q4FUZ8, GLYA_PSYA2 ;
DR   Q1QE01, GLYA_PSYCK ;  A1SUU0, GLYA_PSYIN ;  A5WH82, GLYA_PSYWF ;
DR   Q9V1B2, GLYA_PYRAB ;  Q8ZYF9, GLYA_PYRAE ;  A4WGZ8, GLYA_PYRAR ;
DR   A3MS37, GLYA_PYRCJ ;  Q8U039, GLYA_PYRFU ;  O59347, GLYA_PYRHO ;
DR   A1RTI0, GLYA_PYRIL ;  Q5JF06, GLYA_PYRKO ;  B2U7G7, GLYA_RALPJ ;
DR   Q2KA25, GLYA_RHIEC ;  Q1MIU5, GLYA_RHIL3 ;  Q7UQN2, GLYA_RHOBA ;
DR   B6IMT0, GLYA_RHOCS ;  Q21V29, GLYA_RHOFD ;  Q2IWS4, GLYA_RHOP2 ;
DR   Q07MT9, GLYA_RHOP5 ;  Q214H7, GLYA_RHOPB ;  Q3IZN2, GLYA_RHOS4 ;
DR   C3PLL9, GLYA_RICAE ;  A8GPR4, GLYA_RICAH ;  A8GUH4, GLYA_RICB8 ;
DR   Q1RGX5, GLYA_RICBR ;  A8EZU3, GLYA_RICCK ;  Q92GH7, GLYA_RICCN ;
DR   Q4UK96, GLYA_RICFE ;  A8F2M5, GLYA_RICM5 ;  O08370, GLYA_RICPR ;
DR   C4K1H9, GLYA_RICPU ;  B0BV27, GLYA_RICRO ;  A8GTI9, GLYA_RICRS ;
DR   Q68W07, GLYA_RICTY ;  A7NIF2, GLYA_ROSCS ;  A5UQB7, GLYA_ROSS1 ;
DR   A1AWS2, GLYA_RUTMC ;  Q21NP8, GLYA_SACD2 ;  B5F1D2, GLYA_SALA4 ;
DR   A8M1D3, GLYA_SALAI ;  A9MHI3, GLYA_SALAR ;  Q57LF7, GLYA_SALCH ;
DR   B4TDC8, GLYA_SALHS ;  B4T1D1, GLYA_SALNS ;  Q5PII3, GLYA_SALPA ;
DR   A9N1W0, GLYA_SALPB ;  C0PYJ5, GLYA_SALPC ;  B5BAV4, GLYA_SALPK ;
DR   Q2S4G9, GLYA_SALRD ;  B4TRY8, GLYA_SALSV ;  P0A2E2, GLYA_SALTI ;
DR   A4X6P4, GLYA_SALTO ;  P0A2E1, GLYA_SALTY ;  A8GHZ4, GLYA_SERP5 ;
DR   A1S4B5, GLYA_SHEAM ;  B8E6W1, GLYA_SHEB2 ;  A3D7D0, GLYA_SHEB5 ;
DR   A6WR52, GLYA_SHEB8 ;  A9KYJ6, GLYA_SHEB9 ;  Q12Q48, GLYA_SHEDO ;
DR   Q086C9, GLYA_SHEFN ;  B0TJY5, GLYA_SHEHH ;  A3QC57, GLYA_SHELP ;
DR   Q8EBN8, GLYA_SHEON ;  A8H1Q0, GLYA_SHEPA ;  A4Y966, GLYA_SHEPC ;
DR   B8CJM7, GLYA_SHEPW ;  A0KU60, GLYA_SHESA ;  A8FSQ9, GLYA_SHESH ;
DR   Q0HL93, GLYA_SHESM ;  Q0HXJ6, GLYA_SHESR ;  A1RHD0, GLYA_SHESW ;
DR   B1KJJ9, GLYA_SHEWM ;  B2TXW4, GLYA_SHIB3 ;  Q31XT6, GLYA_SHIBS ;
DR   Q32D21, GLYA_SHIDS ;  Q0T1W9, GLYA_SHIF8 ;  P0A827, GLYA_SHIFL ;
DR   Q3YZ04, GLYA_SHISS ;  Q5LPA8, GLYA_SILPO ;  Q1GGA4, GLYA_SILST ;
DR   Q2NS25, GLYA_SODGM ;  Q01QZ0, GLYA_SOLUE ;  A9GPH2, GLYA_SORC5 ;
DR   Q1GV11, GLYA_SPHAL ;  A5V5D1, GLYA_SPHWW ;  A7X4V7, GLYA_STAA1 ;
DR   A6U3J8, GLYA_STAA2 ;  Q2FF15, GLYA_STAA3 ;  Q2FWE5, GLYA_STAA8 ;
DR   A5IUQ8, GLYA_STAA9 ;  Q2YUJ1, GLYA_STAAB ;  Q5HE87, GLYA_STAAC ;
DR   A6QIV7, GLYA_STAAE ;  P66803, GLYA_STAAM ;  P99091, GLYA_STAAN ;
DR   Q6GEW2, GLYA_STAAR ;  Q6G7J7, GLYA_STAAS ;  A8YY80, GLYA_STAAT ;
DR   P66804, GLYA_STAAW ;  B9DMF3, GLYA_STACT ;  Q5HMB0, GLYA_STAEQ ;
DR   Q8CRN3, GLYA_STAES ;  Q4L7Z4, GLYA_STAHJ ;  A3DNJ6, GLYA_STAMF ;
DR   Q49Z60, GLYA_STAS1 ;  Q3K122, GLYA_STRA1 ;  Q8E5C6, GLYA_STRA3 ;
DR   Q8DZM7, GLYA_STRA5 ;  Q82JI0, GLYA_STRAW ;  O86565, GLYA_STRCO ;
DR   C0M6L7, GLYA_STRE4 ;  B4U313, GLYA_STREM ;  A8AXC8, GLYA_STRGC ;
DR   B1VZY7, GLYA_STRGG ;  B4SJB0, GLYA_STRM5 ;  B2FNK2, GLYA_STRMK ;
DR   Q8DU67, GLYA_STRMU ;  Q99ZP1, GLYA_STRP1 ;  Q04KR0, GLYA_STRP2 ;
DR   P0DF70, GLYA_STRP3 ;  B5E4E3, GLYA_STRP4 ;  Q5XC65, GLYA_STRP6 ;
DR   C1C6Z9, GLYA_STRP7 ;  Q8P122, GLYA_STRP8 ;  Q1JBR5, GLYA_STRPB ;
DR   Q1JLP8, GLYA_STRPC ;  Q1JGU8, GLYA_STRPD ;  Q1J6L7, GLYA_STRPF ;
DR   A2REH5, GLYA_STRPG ;  B1IBI3, GLYA_STRPI ;  B8ZPH5, GLYA_STRPJ ;
DR   Q48TK6, GLYA_STRPM ;  Q97R16, GLYA_STRPN ;  P0DF71, GLYA_STRPQ ;
DR   B2IPI0, GLYA_STRPS ;  B5XLJ2, GLYA_STRPZ ;  Q8DPZ0, GLYA_STRR6 ;
DR   A4W0W9, GLYA_STRS2 ;  C0MF11, GLYA_STRS7 ;  A3CN08, GLYA_STRSV ;
DR   A4VUM9, GLYA_STRSY ;  Q5M0B4, GLYA_STRT1 ;  Q5M4W1, GLYA_STRT2 ;
DR   Q03L77, GLYA_STRTD ;  B9DS48, GLYA_STRU0 ;  C1CE16, GLYA_STRZJ ;
DR   C1CKA2, GLYA_STRZP ;  C1CRE4, GLYA_STRZT ;  Q4J937, GLYA_SULAC ;
DR   C3N6F2, GLYA_SULIA ;  C4KHW7, GLYA_SULIK ;  C3MQN2, GLYA_SULIL ;
DR   C3MWN2, GLYA_SULIM ;  C3NGT4, GLYA_SULIN ;  C3NEW0, GLYA_SULIY ;
DR   A6Q7H8, GLYA_SULNB ;  Q9UWT5, GLYA_SULSO ;  B2V9M1, GLYA_SULSY ;
DR   Q971K4, GLYA_SULTO ;  Q67N41, GLYA_SYMTH ;  Q2LQM6, GLYA_SYNAS ;
DR   Q31RK5, GLYA_SYNE7 ;  A0LI16, GLYA_SYNFM ;  Q2JT50, GLYA_SYNJA ;
DR   Q2JI36, GLYA_SYNJB ;  Q5N2P9, GLYA_SYNP6 ;  A5GIG4, GLYA_SYNPW ;
DR   Q7U9J7, GLYA_SYNPX ;  A5GWH2, GLYA_SYNR3 ;  Q0IDD8, GLYA_SYNS3 ;
DR   Q3AW18, GLYA_SYNS9 ;  Q3AN03, GLYA_SYNSC ;  Q0AUC3, GLYA_SYNWW ;
DR   P77962, GLYA_SYNY3 ;  C5BS91, GLYA_TERTT ;  B7IHE6, GLYA_THEAB ;
DR   Q9HI38, GLYA_THEAC ;  Q8DH33, GLYA_THEEB ;  Q47MD6, GLYA_THEFY ;
DR   C5A6G2, GLYA_THEGJ ;  A8F595, GLYA_THELT ;  A6LKU9, GLYA_THEM4 ;
DR   Q9WZH9, GLYA_THEMA ;  B9KAQ7, GLYA_THENN ;  B1YA29, GLYA_THENV ;
DR   B6YVY6, GLYA_THEON ;  A5IJ65, GLYA_THEP1 ;  B0K742, GLYA_THEP3 ;
DR   B0K631, GLYA_THEPX ;  B9KZ44, GLYA_THERP ;  B1L7Y6, GLYA_THESQ ;
DR   Q72IH2, GLYA_THET2 ;  Q5SI56, GLYA_THET8 ;  Q8R887, GLYA_THETN ;
DR   Q97CQ5, GLYA_THEVO ;  B5YFZ0, GLYA_THEYD ;  Q31FS6, GLYA_THICR ;
DR   Q3SGX5, GLYA_THIDA ;  C4LAE6, GLYA_TOLAT ;  O83349, GLYA_TREPA ;
DR   Q111H1, GLYA_TRIEI ;  P66806, GLYA_TROW8 ;  P66805, GLYA_TROWT ;
DR   Q0W3U6, GLYA_UNCMA ;  B1GYQ9, GLYA_UNCTG ;  C5CPY0, GLYA_VARPS ;
DR   A1WQP4, GLYA_VEREI ;  A5CWI3, GLYA_VESOH ;  Q5E706, GLYA_VIBF1 ;
DR   B5FBF0, GLYA_VIBFM ;  Q8D253, GLYA_WIGBR ;  Q73GC3, GLYA_WOLPM ;
DR   B3CM26, GLYA_WOLPP ;  Q7MAR0, GLYA_WOLSU ;  Q5GTS7, GLYA_WOLTR ;
DR   C0R4C7, GLYA_WOLWR ;  Q8PPE3, GLYA_XANAC ;  Q3BXI8, GLYA_XANC5 ;
DR   Q4UQT6, GLYA_XANC8 ;  B0RVE1, GLYA_XANCB ;  Q8PCN4, GLYA_XANCP ;
DR   Q2NZ83, GLYA_XANOM ;  B2SNV6, GLYA_XANOP ;  Q5GW07, GLYA_XANOR ;
DR   B2I8R0, GLYA_XYLF2 ;  Q9PET2, GLYA_XYLFA ;  B0U4K9, GLYA_XYLFM ;
DR   Q87AS2, GLYA_XYLFT ;  A1JKP3, GLYA_YERE8 ;  A7FFW1, GLYA_YERP3 ;
DR   Q1C5G0, GLYA_YERPA ;  B2K9S8, GLYA_YERPB ;  Q8ZCR1, GLYA_YERPE ;
DR   A9R8C1, GLYA_YERPG ;  Q1CKB8, GLYA_YERPN ;  A4TMW4, GLYA_YERPP ;
DR   Q667X1, GLYA_YERPS ;  B1JRX7, GLYA_YERPY ;  Q5NN85, GLYA_ZYMMO ;
DR   Q54Z26, GLYC1_DICDI;  Q54EW1, GLYC2_DICDI;  Q75BQ6, GLYC_ASHGO ;
DR   Q5E9P9, GLYC_BOVIN ;  Q60V73, GLYC_CAEBR ;  P50432, GLYC_CAEEL ;
DR   O13426, GLYC_CANAL ;  Q6FUP6, GLYC_CANGA ;  O62585, GLYC_ENCCU ;
DR   P34896, GLYC_HUMAN ;  P50431, GLYC_MOUSE ;  P34898, GLYC_NEUCR ;
DR   Q5RFK5, GLYC_PONAB ;  P07511, GLYC_RABIT ;  Q10104, GLYC_SCHPO ;
DR   P35623, GLYC_SHEEP ;  P37291, GLYC_YEAST ;  O13972, GLYD_SCHPO ;
DR   Q9SZJ5, GLYM_ARATH ;  Q758F0, GLYM_ASHGO ;  Q3SZ20, GLYM_BOVIN ;
DR   O13425, GLYM_CANAL ;  Q6FQ44, GLYM_CANGA ;  P49357, GLYM_FLAPR ;
DR   P34897, GLYM_HUMAN ;  Q6CLQ5, GLYM_KLULA ;  Q7S5N8, GLYM_NEUCR ;
DR   P34899, GLYM_PEA   ;  P14519, GLYM_RABIT ;  P50433, GLYM_SOLTU ;
DR   P37292, GLYM_YEAST ;  P49358, GLYN_FLAPR ;
//
ID   2.1.2.2
DE   Phosphoribosylglycinamide formyltransferase.
AN   2-amino-N-ribosylacetamide 5'-phosphate transformylase.
AN   5'-phosphoribosylglycinamide transformylase.
AN   5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide
AN   transformylase.
AN   GAR formyltransferase.
AN   GAR TFase.
AN   GAR transformylase.
AN   GART.
AN   Glycinamide ribonucleotide transformylase.
CA   10-formyltetrahydrofolate + N(1)-(5-phospho-D-ribosyl)glycinamide =
CA   tetrahydrofolate + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide.
PR   PROSITE; PDOC00319;
DR   Q59A32, PUR2_BOVIN ;  P21872, PUR2_CHICK ;  Q26255, PUR2_CHITE ;
DR   P00967, PUR2_DROME ;  P16340, PUR2_DROPS ;  P22102, PUR2_HUMAN ;
DR   Q64737, PUR2_MOUSE ;  P52422, PUR3_ARATH ;  P12040, PUR3_BACSU ;
DR   Q54I60, PUR3_DICDI ;  P08179, PUR3_ECOLI ;  P43846, PUR3_HAEIN ;
DR   Q9UUK7, PUR3_SCHPO ;  Q42805, PUR3_SOYBN ;  Q5HH12, PUR3_STAAC ;
DR   P65897, PUR3_STAAM ;  P99162, PUR3_STAAN ;  Q6GI12, PUR3_STAAR ;
DR   Q6GAE1, PUR3_STAAS ;  Q8NX89, PUR3_STAAW ;  Q5HQ98, PUR3_STAEQ ;
DR   Q8CT28, PUR3_STAES ;  P52423, PUR3_VIGUN ;  P04161, PUR3_YEAST ;
//
ID   2.1.2.3
DE   Phosphoribosylaminoimidazolecarboxamide formyltransferase.
AN   10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-
AN   imidazolecarboxamide formyltransferase.
AN   5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase.
AN   5-amino-1-ribosyl-4-imidazolecarboxamide 5'-phosphate transformylase.
AN   5-amino-4-imidazolecarboxamide ribonucleotide transformylase.
AN   5-amino-4-imidazolecarboxamide ribotide transformylase.
AN   AICAR formyltransferase.
AN   AICAR transformylase.
AN   Aminoimidazolecarboxamide ribonucleotide transformylase.
CA   10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-
CA   carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D-
CA   ribosyl)imidazole-4-carboxamide.
DR   P54113, PUR91_YEAST;  P38009, PUR92_YEAST;  B0BZH9, PUR9_ACAM1 ;
DR   A5FUH4, PUR9_ACICJ ;  B7J5P7, PUR9_ACIF2 ;  B5EL42, PUR9_ACIF5 ;
DR   A0KGJ2, PUR9_AERHH ;  A4SR98, PUR9_AERS4 ;  B9JEU9, PUR9_AGRRK ;
DR   Q8UBM8, PUR9_AGRT5 ;  Q0VMY5, PUR9_ALCBS ;  B6ENA8, PUR9_ALISL ;
DR   A6TLS7, PUR9_ALKMQ ;  A8MLI9, PUR9_ALKOO ;  Q46480, PUR9_ALLVD ;
DR   B4S133, PUR9_ALTMD ;  B8JHC9, PUR9_ANAD2 ;  Q2IKQ7, PUR9_ANADE ;
DR   A7HA60, PUR9_ANADF ;  B4UJ61, PUR9_ANASK ;  B9MS89, PUR9_ANATD ;
DR   Q3M6G3, PUR9_ANAVT ;  B7GFU2, PUR9_ANOFW ;  O67775, PUR9_AQUAE ;
DR   C1DLJ1, PUR9_AZOVD ;  C3PBN4, PUR9_BACAA ;  C3L536, PUR9_BACAC ;
DR   A0R900, PUR9_BACAH ;  Q81ZG8, PUR9_BACAN ;  B7JM89, PUR9_BACC0 ;
DR   Q73EN1, PUR9_BACC1 ;  B7IUV7, PUR9_BACC2 ;  C1EV67, PUR9_BACC3 ;
DR   B7H4U0, PUR9_BACC4 ;  B7HS36, PUR9_BACC7 ;  A7GKI2, PUR9_BACCN ;
DR   B9J1K9, PUR9_BACCQ ;  Q81IP9, PUR9_BACCR ;  Q63GS9, PUR9_BACCZ ;
DR   Q9KF53, PUR9_BACHD ;  Q6HPA0, PUR9_BACHK ;  Q5WJ82, PUR9_BACSK ;
DR   P12048, PUR9_BACSU ;  Q8A155, PUR9_BACTN ;  A9VRF5, PUR9_BACWK ;
DR   A1UR09, PUR9_BARBK ;  Q6G5S5, PUR9_BARHE ;  Q6FYG4, PUR9_BARQU ;
DR   A9IZD0, PUR9_BART1 ;  Q1LU51, PUR9_BAUCH ;  B3DRY6, PUR9_BIFLD ;
DR   Q8G6B1, PUR9_BIFLO ;  Q0VCK0, PUR9_BOVIN ;  C0QXU6, PUR9_BRAHW ;
DR   Q89WU7, PUR9_BRAJA ;  B2S7P0, PUR9_BRUA1 ;  Q2YLH0, PUR9_BRUA2 ;
DR   Q57B71, PUR9_BRUAB ;  A9M854, PUR9_BRUC2 ;  C0RF67, PUR9_BRUMB ;
DR   P67539, PUR9_BRUME ;  A5VSF8, PUR9_BRUO2 ;  A9WWU1, PUR9_BRUSI ;
DR   P67540, PUR9_BRUSU ;  B8D8J3, PUR9_BUCA5 ;  P57143, PUR9_BUCAI ;
DR   Q8KA70, PUR9_BUCAP ;  B8D6U7, PUR9_BUCAT ;  Q89B23, PUR9_BUCBP ;
DR   B1YTE2, PUR9_BURA4 ;  Q1BZ33, PUR9_BURCA ;  B1JVV6, PUR9_BURCC ;
DR   A0K4L7, PUR9_BURCH ;  B4EES4, PUR9_BURCJ ;  Q0BI80, PUR9_BURCM ;
DR   A9AH70, PUR9_BURM1 ;  A3MP76, PUR9_BURM7 ;  A2S597, PUR9_BURM9 ;
DR   Q62HA6, PUR9_BURMA ;  A1V068, PUR9_BURMS ;  A3NZ64, PUR9_BURP0 ;
DR   Q3JNS8, PUR9_BURP1 ;  A3NDF2, PUR9_BURP6 ;  B2JGU1, PUR9_BURP8 ;
DR   B2SYJ7, PUR9_BURPP ;  Q63QX8, PUR9_BURPS ;  Q39JI8, PUR9_BURS3 ;
DR   Q2SZ52, PUR9_BURTA ;  A4JBL5, PUR9_BURVG ;  Q13UC4, PUR9_BURXL ;
DR   A4XKZ2, PUR9_CALS8 ;  A7ZCZ7, PUR9_CAMC1 ;  A7GYY6, PUR9_CAMC5 ;
DR   A8FM07, PUR9_CAMJ8 ;  A7H375, PUR9_CAMJD ;  Q9PNY2, PUR9_CAMJE ;
DR   A1VZU4, PUR9_CAMJJ ;  Q5HUK6, PUR9_CAMJR ;  Q9ABY4, PUR9_CAUCR ;
DR   P31335, PUR9_CHICK ;  A9WEK8, PUR9_CHLAA ;  Q3ATZ1, PUR9_CHLCH ;
DR   B3EEI0, PUR9_CHLL2 ;  B3QQA5, PUR9_CHLP8 ;  B3ELV3, PUR9_CHLPB ;
DR   A1BE85, PUR9_CHLPD ;  B3QS62, PUR9_CHLT3 ;  Q8KFK6, PUR9_CHLTE ;
DR   Q7P0M1, PUR9_CHRVO ;  A8AKS0, PUR9_CITK8 ;  Q97J91, PUR9_CLOAB ;
DR   A7FXD3, PUR9_CLOB1 ;  C3L2U9, PUR9_CLOB6 ;  A6LSB3, PUR9_CLOB8 ;
DR   B2V3C3, PUR9_CLOBA ;  B2TN76, PUR9_CLOBB ;  A5I5V9, PUR9_CLOBH ;
DR   C1FV76, PUR9_CLOBJ ;  B1IL57, PUR9_CLOBK ;  A7GH96, PUR9_CLOBL ;
DR   B1KZ55, PUR9_CLOBM ;  B8I490, PUR9_CLOCE ;  Q18CW0, PUR9_CLOD6 ;
DR   B9E4K6, PUR9_CLOK1 ;  A5N0Q0, PUR9_CLOK5 ;  A0Q1J0, PUR9_CLONN ;
DR   Q0TTB0, PUR9_CLOP1 ;  Q8XMK2, PUR9_CLOPE ;  Q0SV48, PUR9_CLOPS ;
DR   Q892X3, PUR9_CLOTE ;  A3DEU9, PUR9_CLOTH ;  Q489F4, PUR9_COLP3 ;
DR   C3PF03, PUR9_CORA7 ;  Q9RHX6, PUR9_CORAM ;  Q6NID8, PUR9_CORDI ;
DR   Q8FR29, PUR9_COREF ;  A4QCK4, PUR9_CORGB ;  Q8NS21, PUR9_CORGL ;
DR   Q0KEC0, PUR9_CUPNH ;  Q475R4, PUR9_CUPPJ ;  B2AH76, PUR9_CUPTR ;
DR   B8HPG4, PUR9_CYAP4 ;  B7KGS0, PUR9_CYAP7 ;  B7K3N8, PUR9_CYAP8 ;
DR   C1CWJ7, PUR9_DEIDV ;  Q1J119, PUR9_DEIGD ;  Q9RW01, PUR9_DEIRA ;
DR   B8FP05, PUR9_DESHD ;  Q24QH6, PUR9_DESHY ;  Q86L14, PUR9_DICDI ;
DR   A8LMD0, PUR9_DINSH ;  A7ZUM3, PUR9_ECO24 ;  B7UPG1, PUR9_ECO27 ;
DR   B7MIZ2, PUR9_ECO45 ;  B7LAV3, PUR9_ECO55 ;  Q8X611, PUR9_ECO57 ;
DR   B5Z0A3, PUR9_ECO5E ;  B7NRT9, PUR9_ECO7I ;  B7MRD0, PUR9_ECO81 ;
DR   B7M7R5, PUR9_ECO8A ;  C5A0U7, PUR9_ECOBW ;  B1XC09, PUR9_ECODH ;
DR   A8A7A6, PUR9_ECOHS ;  A1AIH7, PUR9_ECOK1 ;  Q0TA59, PUR9_ECOL5 ;
DR   Q8FB68, PUR9_ECOL6 ;  B1IUP1, PUR9_ECOLC ;  P15639, PUR9_ECOLI ;
DR   B7NFU7, PUR9_ECOLU ;  B6I5L8, PUR9_ECOSE ;  B1LPG6, PUR9_ECOSM ;
DR   Q1R5X1, PUR9_ECOUT ;  B2KCF7, PUR9_ELUMP ;  Q833Z3, PUR9_ENTFA ;
DR   A7MJ89, PUR9_ENTS8 ;  Q6DAL2, PUR9_ERWCT ;  B2VG81, PUR9_ERWT9 ;
DR   B7LUJ6, PUR9_ESCF3 ;  Q8REV6, PUR9_FUSNN ;  B5EBF9, PUR9_GEOBB ;
DR   B3E7F6, PUR9_GEOLS ;  Q39RK1, PUR9_GEOMG ;  B9M4Q6, PUR9_GEOSF ;
DR   Q74FJ9, PUR9_GEOSL ;  C6E5Z3, PUR9_GEOSM ;  A5G879, PUR9_GEOUR ;
DR   P43852, PUR9_HAEIN ;  Q0I557, PUR9_HAES1 ;  B0UWT1, PUR9_HAES2 ;
DR   B0TEC5, PUR9_HELMI ;  A4G1U6, PUR9_HERAR ;  P31939, PUR9_HUMAN ;
DR   A6SUQ1, PUR9_JANMA ;  Q28K03, PUR9_JANSC ;  B5XYD2, PUR9_KLEP3 ;
DR   A6TGR3, PUR9_KLEP7 ;  Q5FIV5, PUR9_LACAC ;  Q037V3, PUR9_LACC3 ;
DR   B3WF93, PUR9_LACCB ;  Q1G9G2, PUR9_LACDA ;  Q049M1, PUR9_LACDB ;
DR   Q9CFG0, PUR9_LACLA ;  A2RJY0, PUR9_LACLM ;  Q02Y66, PUR9_LACLS ;
DR   Q88U29, PUR9_LACPL ;  A5VHU2, PUR9_LACRD ;  B2G5C2, PUR9_LACRJ ;
DR   Q1WU55, PUR9_LACS1 ;  Q38XW3, PUR9_LACSS ;  C1D6F1, PUR9_LARHH ;
DR   Q6AD62, PUR9_LEIXX ;  B0SGW3, PUR9_LEPBA ;  Q04T56, PUR9_LEPBJ ;
DR   Q051H8, PUR9_LEPBL ;  B0SQ10, PUR9_LEPBP ;  Q72RT5, PUR9_LEPIC ;
DR   Q8F3W6, PUR9_LEPIN ;  B1MY42, PUR9_LEUCK ;  Q03Y85, PUR9_LEUMM ;
DR   Q92AP3, PUR9_LISIN ;  C1KW64, PUR9_LISMC ;  Q71YQ3, PUR9_LISMF ;
DR   B8DDZ2, PUR9_LISMH ;  Q8Y6C5, PUR9_LISMO ;  A0AJL9, PUR9_LISW6 ;
DR   B1HTV8, PUR9_LYSSC ;  B9EAZ2, PUR9_MACCJ ;  A0LDB0, PUR9_MAGSM ;
DR   Q11CT4, PUR9_MESSB ;  Q1H4G7, PUR9_METFK ;  B0JL55, PUR9_MICAN ;
DR   Q2RGU9, PUR9_MOOTA ;  Q9CWJ9, PUR9_MOUSE ;  P67542, PUR9_MYCBO ;
DR   A1KH91, PUR9_MYCBP ;  C1ALU3, PUR9_MYCBT ;  B8ZU05, PUR9_MYCLB ;
DR   Q9Z5H5, PUR9_MYCLE ;  B2HEC3, PUR9_MYCMM ;  Q9RAJ5, PUR9_MYCPA ;
DR   A3Q5N7, PUR9_MYCSJ ;  A1UL88, PUR9_MYCSK ;  Q1B3W0, PUR9_MYCSS ;
DR   A5U0Z7, PUR9_MYCTA ;  P67541, PUR9_MYCTU ;  A0PWC5, PUR9_MYCUA ;
DR   Q1D898, PUR9_MYXXD ;  B2A5W1, PUR9_NATTJ ;  Q5F6T1, PUR9_NEIG1 ;
DR   B4RP71, PUR9_NEIG2 ;  A9M4I2, PUR9_NEIM0 ;  Q9JUQ8, PUR9_NEIMA ;
DR   Q9JZM7, PUR9_NEIMB ;  A1KTP9, PUR9_NEIMF ;  Q3JC90, PUR9_NITOC ;
DR   A1SMP8, PUR9_NOCSJ ;  B2IX54, PUR9_NOSP7 ;  Q8YSJ2, PUR9_NOSS1 ;
DR   Q8CXK7, PUR9_OCEIH ;  A6WXV3, PUR9_OCHA4 ;  Q04EU6, PUR9_OENOB ;
DR   A1B5K8, PUR9_PARDP ;  A7HSQ6, PUR9_PARL1 ;  P57828, PUR9_PASMU ;
DR   C6DHT5, PUR9_PECCP ;  Q03E83, PUR9_PEDPA ;  Q3A2D6, PUR9_PELCD ;
DR   Q3B5R1, PUR9_PELLD ;  B4SDT6, PUR9_PELPB ;  A1AS76, PUR9_PELPD ;
DR   C0QRH2, PUR9_PERMH ;  A9BIX9, PUR9_PETMO ;  Q7N954, PUR9_PHOLL ;
DR   B1XS23, PUR9_POLNS ;  A4T025, PUR9_POLSQ ;  Q5R5C2, PUR9_PONAB ;
DR   B4S3H9, PUR9_PROA2 ;  Q6A6Y8, PUR9_PROAC ;  A3PAY7, PUR9_PROM0 ;
DR   A2C098, PUR9_PROM1 ;  A8G2S6, PUR9_PROM2 ;  A2CCK6, PUR9_PROM3 ;
DR   A9BDN8, PUR9_PROM4 ;  A2BUP7, PUR9_PROM5 ;  Q31CR6, PUR9_PROM9 ;
DR   Q7VDS0, PUR9_PROMA ;  B4EYT2, PUR9_PROMH ;  Q7TUM7, PUR9_PROMM ;
DR   Q7TUG1, PUR9_PROMP ;  A2BP65, PUR9_PROMS ;  Q46HA8, PUR9_PROMT ;
DR   A4SDE6, PUR9_PROVI ;  A6VCW0, PUR9_PSEA7 ;  B7V1R6, PUR9_PSEA8 ;
DR   Q02FG6, PUR9_PSEAB ;  Q9HUV9, PUR9_PSEAE ;  Q1I4C1, PUR9_PSEE4 ;
DR   Q4KIX5, PUR9_PSEF5 ;  C3K6E0, PUR9_PSEFS ;  Q3IIC3, PUR9_PSEHT ;
DR   A4XQ60, PUR9_PSEMY ;  A5W9K7, PUR9_PSEP1 ;  B0KJZ6, PUR9_PSEPG ;
DR   Q88DK3, PUR9_PSEPK ;  B1J5T3, PUR9_PSEPW ;  Q87VR9, PUR9_PSESM ;
DR   A4VPK9, PUR9_PSEU5 ;  Q4FRN8, PUR9_PSYA2 ;  Q1QA75, PUR9_PSYCK ;
DR   A1SZJ2, PUR9_PSYIN ;  A5WFX4, PUR9_PSYWF ;  Q1LRB3, PUR9_RALME ;
DR   B2UFL5, PUR9_RALPJ ;  Q8Y232, PUR9_RALSO ;  O35567, PUR9_RAT   ;
DR   B3PS36, PUR9_RHIE6 ;  Q2K2T6, PUR9_RHIEC ;  Q1MA35, PUR9_RHIL3 ;
DR   Q98ES7, PUR9_RHILO ;  B5ZV31, PUR9_RHILW ;  Q92KX6, PUR9_RHIME ;
DR   C3MAR5, PUR9_RHISN ;  Q7UKJ8, PUR9_RHOBA ;  Q2RN46, PUR9_RHORT ;
DR   A3PNE9, PUR9_RHOS1 ;  Q3IYU8, PUR9_RHOS4 ;  A4WWQ0, PUR9_RHOS5 ;
DR   B9KP36, PUR9_RHOSK ;  Q16CE0, PUR9_ROSDO ;  B5F1I9, PUR9_SALA4 ;
DR   A9MHC3, PUR9_SALAR ;  B5FQM1, PUR9_SALDC ;  B5QYG1, PUR9_SALEP ;
DR   B5RFH8, PUR9_SALG2 ;  B4TDF3, PUR9_SALHS ;  B4T108, PUR9_SALNS ;
DR   Q5PKA9, PUR9_SALPA ;  A9N0L8, PUR9_SALPB ;  C0Q2T8, PUR9_SALPC ;
DR   B5BJS5, PUR9_SALPK ;  B4TQL6, PUR9_SALSV ;  Q8Z335, PUR9_SALTI ;
DR   P26978, PUR9_SALTY ;  O74928, PUR9_SCHPO ;  A8G8G3, PUR9_SERP5 ;
DR   A1S2J9, PUR9_SHEAM ;  Q12IP4, PUR9_SHEDO ;  Q088G0, PUR9_SHEFN ;
DR   B0TR91, PUR9_SHEHH ;  A3QII0, PUR9_SHELP ;  Q8EJM1, PUR9_SHEON ;
DR   A8GZM3, PUR9_SHEPA ;  B8CTW4, PUR9_SHEPW ;  A8FQD4, PUR9_SHESH ;
DR   B1KNA0, PUR9_SHEWM ;  B2TWJ3, PUR9_SHIB3 ;  Q31TZ1, PUR9_SHIBS ;
DR   Q32AH9, PUR9_SHIDS ;  Q0SXZ4, PUR9_SHIF8 ;  Q83IR9, PUR9_SHIFL ;
DR   Q3YUX8, PUR9_SHISS ;  Q5LN38, PUR9_SILPO ;  Q1GKJ2, PUR9_SILST ;
DR   A6UED3, PUR9_SINMW ;  Q2NWQ7, PUR9_SODGM ;  A9GIT1, PUR9_SORC5 ;
DR   A6U0P1, PUR9_STAA2 ;  Q2FI05, PUR9_STAA3 ;  Q2FZI6, PUR9_STAA8 ;
DR   A5IRW0, PUR9_STAA9 ;  Q2YX50, PUR9_STAAB ;  Q5HH11, PUR9_STAAC ;
DR   A6QFT1, PUR9_STAAE ;  P67543, PUR9_STAAM ;  P67544, PUR9_STAAN ;
DR   Q6GI11, PUR9_STAAR ;  Q6GAE0, PUR9_STAAS ;  Q8NX88, PUR9_STAAW ;
DR   B9DQ42, PUR9_STACT ;  Q5HQ97, PUR9_STAEQ ;  Q8CT27, PUR9_STAES ;
DR   Q4L582, PUR9_STAHJ ;  Q49WJ7, PUR9_STAS1 ;  Q3K3Z7, PUR9_STRA1 ;
DR   P67545, PUR9_STRA3 ;  P67546, PUR9_STRA5 ;  Q9KY50, PUR9_STRCO ;
DR   C0MB61, PUR9_STRE4 ;  A8AUA2, PUR9_STRGC ;  B4SL92, PUR9_STRM5 ;
DR   B2FJP9, PUR9_STRMK ;  Q8DWK8, PUR9_STRMU ;  Q04N19, PUR9_STRP2 ;
DR   P0DD60, PUR9_STRP3 ;  B5E5J9, PUR9_STRP4 ;  Q5XEF2, PUR9_STRP6 ;
DR   C1C9V4, PUR9_STRP7 ;  Q8P310, PUR9_STRP8 ;  Q1JE78, PUR9_STRPB ;
DR   Q1JP34, PUR9_STRPC ;  Q1JJ80, PUR9_STRPD ;  Q1J934, PUR9_STRPF ;
DR   B1I7V8, PUR9_STRPI ;  B8ZJN3, PUR9_STRPJ ;  Q48VY9, PUR9_STRPM ;
DR   Q97T99, PUR9_STRPN ;  P0DD61, PUR9_STRPQ ;  B5XJ20, PUR9_STRPZ ;
DR   Q8DRM1, PUR9_STRR6 ;  A4VYK5, PUR9_STRS2 ;  C0MC89, PUR9_STRS7 ;
DR   Q9F1T4, PUR9_STRSU ;  A4VSB5, PUR9_STRSY ;  Q03MZ6, PUR9_STRTD ;
DR   B9DSR6, PUR9_STRU0 ;  C1CBM7, PUR9_STRZJ ;  C1CHW2, PUR9_STRZP ;
DR   C1CNS9, PUR9_STRZT ;  Q67KG3, PUR9_SYMTH ;  Q31R91, PUR9_SYNE7 ;
DR   A5GIF4, PUR9_SYNPW ;  Q7TTX6, PUR9_SYNPX ;  Q0IDE8, PUR9_SYNS3 ;
DR   Q3B083, PUR9_SYNS9 ;  Q3AN13, PUR9_SYNSC ;  Q0AW31, PUR9_SYNWW ;
DR   P74741, PUR9_SYNY3 ;  Q8DIN5, PUR9_THEEB ;  Q9X0X6, PUR9_THEMA ;
DR   B0KBQ1, PUR9_THEP3 ;  B0K3Q8, PUR9_THEPX ;  Q8RC55, PUR9_THETN ;
DR   B5YLE5, PUR9_THEYD ;  Q31II8, PUR9_THICR ;  C4LA41, PUR9_TOLAT ;
DR   Q116T4, PUR9_TRIEI ;  C5CL84, PUR9_VARPS ;  A5F3U8, PUR9_VIBC3 ;
DR   Q9KV80, PUR9_VIBCH ;  C3LQN2, PUR9_VIBCM ;  Q5E257, PUR9_VIBF1 ;
DR   B5FC70, PUR9_VIBFM ;  A7MXG0, PUR9_VIBHB ;  Q87KT0, PUR9_VIBPA ;
DR   B7VM57, PUR9_VIBSL ;  Q8DD06, PUR9_VIBVU ;  Q7MGT5, PUR9_VIBVY ;
DR   Q8D244, PUR9_WIGBR ;  Q8PQ19, PUR9_XANAC ;  Q3BY85, PUR9_XANC5 ;
DR   Q4UZD2, PUR9_XANC8 ;  B0RN27, PUR9_XANCB ;  Q8PD47, PUR9_XANCP ;
DR   Q2P866, PUR9_XANOM ;  B2SRB2, PUR9_XANOP ;  Q5H5H7, PUR9_XANOR ;
DR   B2I4L7, PUR9_XYLF2 ;  Q9PC10, PUR9_XYLFA ;  B0U7A0, PUR9_XYLFM ;
DR   Q87D58, PUR9_XYLFT ;  A1JIJ7, PUR9_YERE8 ;  A7FNG6, PUR9_YERP3 ;
DR   Q1C1V9, PUR9_YERPA ;  B2K130, PUR9_YERPB ;  Q8ZAR3, PUR9_YERPE ;
DR   A9R8E1, PUR9_YERPG ;  Q1CN60, PUR9_YERPN ;  A4TS14, PUR9_YERPP ;
DR   Q66FN5, PUR9_YERPS ;  B1JJL6, PUR9_YERPY ;
//
ID   2.1.2.4
DE   Glycine formimidoyltransferase.
AN   FIG formiminotransferase.
AN   Formiminoglycine formiminotransferase.
AN   Glycine formiminotransferase.
CA   5-formimidoyltetrahydrofolate + glycine = tetrahydrofolate +
CA   N-formimidoylglycine.
//
ID   2.1.2.5
DE   Glutamate formimidoyltransferase.
AN   Formiminoglutamic acid transferase.
AN   Formiminoglutamic formiminotransferase.
AN   Glutamate formiminotransferase.
AN   Glutamate formyltransferase.
CA   (1) 5-formimidoyltetrahydrofolate + L-glutamate = tetrahydrofolate +
CA   N-formimidoyl-L-glutamate.
CA   (2) 5-formyltetrahydrofolate + L-glutamate = tetrahydrofolate + N-formyl-
CA   L-glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- In eukaryotes occurs as a bifunctional enzyme also having EC 4.3.1.4
CC       activity.
CC   -!- Formerly EC 2.1.2.6.
DR   Q9YH58, FTCD_CHICK ;  Q54JL3, FTCD_DICDI ;  O95954, FTCD_HUMAN ;
DR   Q91XD4, FTCD_MOUSE ;  P53603, FTCD_PIG   ;  O88618, FTCD_RAT   ;
//
ID   2.1.2.6
DE   Transferred entry: 2.1.2.5.
//
ID   2.1.2.7
DE   D-alanine 2-hydroxymethyltransferase.
AN   2-methylserine hydroxymethyltransferase.
AN   D-alanine hydroxymethyltransferase.
CA   5,10-methylenetetrahydrofolate + D-alanine + H(2)O = tetrahydrofolate +
CA   2-methylserine.
CC   -!- Also acts on 2-hydroxymethylserine.
//
ID   2.1.2.8
DE   Deoxycytidylate 5-hydroxymethyltransferase.
AN   dCMP hydroxymethylase.
AN   Deoxycytidylate hydroxymethylase.
AN   Deoxycytidylate hydroxymethyltransferase.
CA   5,10-methylenetetrahydrofolate + H(2)O + deoxycytidylate =
CA   tetrahydrofolate + 5-hydroxymethyldeoxycytidylate.
DR   P18029, DCHM_BPT2  ;  P08773, DCHM_BPT4  ;  P18030, DCHM_BPT6  ;
//
ID   2.1.2.9
DE   Methionyl-tRNA formyltransferase.
AN   Formylmethionyl-transfer ribonucleic synthetase.
AN   Methionyl ribonucleic formyltransferase.
AN   Methionyl-transfer ribonucleate methyltransferase.
AN   Methionyl-transfer ribonucleic transformylase.
AN   Methionyl-transfer RNA transformylase.
AN   Methionyl-tRNA Met formyltransferase.
AN   Methionyl-tRNA transformylase.
AN   N(10)-formyltetrahydrofolic-methionyl-transfer ribonucleic
AN   transformylase.
CA   10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) + H(2)O =
CA   tetrahydrofolate + N-formylmethionyl-tRNA(fMet).
PR   PROSITE; PDOC00319;
DR   A1TW87, FMT_ACIAC  ;  Q6F6P9, FMT_ACIAD  ;  B7GUZ7, FMT_ACIB3  ;
DR   B7I2C3, FMT_ACIB5  ;  B2I2H7, FMT_ACIBC  ;  Q1IIS2, FMT_ACIBL  ;
DR   B0VQ12, FMT_ACIBS  ;  A3MAA1, FMT_ACIBT  ;  B0VAE0, FMT_ACIBY  ;
DR   A0LUE0, FMT_ACIC1  ;  C1F542, FMT_ACIC5  ;  A5FVK3, FMT_ACICJ  ;
DR   B9MI87, FMT_ACIET  ;  B7J3C1, FMT_ACIF2  ;  B5EJ84, FMT_ACIF5  ;
DR   A1WD32, FMT_ACISJ  ;  A3N2N5, FMT_ACTP2  ;  B3GYS0, FMT_ACTP7  ;
DR   B0BRR3, FMT_ACTPJ  ;  A6VKJ6, FMT_ACTSZ  ;  A0KEW9, FMT_AERHH  ;
DR   A4ST58, FMT_AERS4  ;  B9J8C6, FMT_AGRRK  ;  Q8UID0, FMT_AGRT5  ;
DR   B9JQX1, FMT_AGRVS  ;  B2UQR9, FMT_AKKM8  ;  Q0VTE2, FMT_ALCBS  ;
DR   Q0A5C0, FMT_ALHEH  ;  A6TRW7, FMT_ALKMQ  ;  A8MH85, FMT_ALKOO  ;
DR   B8J9P3, FMT_ANAD2  ;  Q2IGM4, FMT_ANADE  ;  Q5PBC7, FMT_ANAMM  ;
DR   Q2GJB8, FMT_ANAPZ  ;  B4UGK3, FMT_ANASK  ;  Q3M7E8, FMT_ANAVT  ;
DR   O67890, FMT_AQUAE  ;  Q5P4H6, FMT_AROAE  ;  A1R5R2, FMT_ARTAT  ;
DR   B8HH63, FMT_ARTCA  ;  A0JVJ5, FMT_ARTS2  ;  B6YQF1, FMT_AZOPC  ;
DR   A7Z4J3, FMT_BACA2  ;  C3P637, FMT_BACAA  ;  C3L761, FMT_BACAC  ;
DR   A0RHN9, FMT_BACAH  ;  Q81WH2, FMT_BACAN  ;  B7JJV3, FMT_BACC0  ;
DR   B7IUM5, FMT_BACC2  ;  C1EP90, FMT_BACC3  ;  B7HDY9, FMT_BACC4  ;
DR   B7HLJ9, FMT_BACC7  ;  A7GRJ6, FMT_BACCN  ;  B9IVF5, FMT_BACCQ  ;
DR   Q819U1, FMT_BACCR  ;  Q636G0, FMT_BACCZ  ;  Q5L975, FMT_BACFN  ;
DR   Q64PD6, FMT_BACFR  ;  Q9K9Y6, FMT_BACHD  ;  Q6HEU9, FMT_BACHK  ;
DR   Q65JS5, FMT_BACLD  ;  A8FD38, FMT_BACP2  ;  Q5WFK7, FMT_BACSK  ;
DR   P94463, FMT_BACSU  ;  Q8A0S6, FMT_BACTN  ;  A6KWC4, FMT_BACV8  ;
DR   A9VTA4, FMT_BACWK  ;  A1UUB5, FMT_BARBK  ;  Q6G5F1, FMT_BARHE  ;
DR   Q6G1G8, FMT_BARQU  ;  A9ILK1, FMT_BART1  ;  Q1LT57, FMT_BAUCH  ;
DR   Q6MJL7, FMT_BDEBA  ;  C5C697, FMT_BEUC1  ;  B8DTX1, FMT_BIFA0  ;
DR   A1A0U2, FMT_BIFAA  ;  B3DRM9, FMT_BIFLD  ;  Q8G3H1, FMT_BIFLO  ;
DR   B7GUP8, FMT_BIFLS  ;  Q7VQC1, FMT_BLOFL  ;  Q493I2, FMT_BLOPB  ;
DR   Q2L0K7, FMT_BORA1  ;  Q0SPA1, FMT_BORAP  ;  Q7WQS8, FMT_BORBR  ;
DR   O51091, FMT_BORBU  ;  B7J100, FMT_BORBZ  ;  B5RKW3, FMT_BORDL  ;
DR   Q662V0, FMT_BORGA  ;  B2S1P9, FMT_BORHD  ;  Q7W1V2, FMT_BORPA  ;
DR   A9IFQ1, FMT_BORPD  ;  Q7VS89, FMT_BORPE  ;  B5RQP3, FMT_BORRA  ;
DR   A1QYL4, FMT_BORT9  ;  O77480, FMT_BOVIN  ;  Q89BP0, FMT_BRAJA  ;
DR   A5ESQ6, FMT_BRASB  ;  A4YLC0, FMT_BRASO  ;  B2SC20, FMT_BRUA1  ;
DR   Q2YJQ3, FMT_BRUA2  ;  Q576T0, FMT_BRUAB  ;  A9MCV9, FMT_BRUC2  ;
DR   C0RMH3, FMT_BRUMB  ;  P64132, FMT_BRUME  ;  A5VVU0, FMT_BRUO2  ;
DR   A9WW44, FMT_BRUSI  ;  P64133, FMT_BRUSU  ;  B8D9S0, FMT_BUCA5  ;
DR   P57564, FMT_BUCAI  ;  Q8K974, FMT_BUCAP  ;  B8D822, FMT_BUCAT  ;
DR   P59557, FMT_BUCBP  ;  B1YPX6, FMT_BURA4  ;  Q1BSJ4, FMT_BURCA  ;
DR   B1K0J5, FMT_BURCC  ;  A0KBJ7, FMT_BURCH  ;  B4E7V8, FMT_BURCJ  ;
DR   Q0BAT6, FMT_BURCM  ;  A9AC69, FMT_BURM1  ;  Q62MT4, FMT_BURMA  ;
DR   A3NQ23, FMT_BURP0  ;  Q3JXE1, FMT_BURP1  ;  A3N4D4, FMT_BURP6  ;
DR   B2JJU4, FMT_BURP8  ;  B2T1K6, FMT_BURPP  ;  Q63YR6, FMT_BURPS  ;
DR   Q39BU5, FMT_BURS3  ;  Q2T2B1, FMT_BURTA  ;  A4JJ22, FMT_BURVG  ;
DR   Q147A4, FMT_BURXL  ;  A4XL81, FMT_CALS8  ;  A7H026, FMT_CAMC5  ;
DR   A0RR35, FMT_CAMFF  ;  A7I168, FMT_CAMHC  ;  A8FJQ3, FMT_CAMJ8  ;
DR   A7H1H2, FMT_CAMJD  ;  Q9PJ28, FMT_CAMJE  ;  A1VXI1, FMT_CAMJJ  ;
DR   Q5HX68, FMT_CAMJR  ;  B9KER4, FMT_CAMLR  ;  Q3AC19, FMT_CARHZ  ;
DR   B8GYF1, FMT_CAUCN  ;  Q9ABE9, FMT_CAUCR  ;  B0T1S7, FMT_CAUSK  ;
DR   A9WAR0, FMT_CHLAA  ;  Q5L722, FMT_CHLAB  ;  B8G4D0, FMT_CHLAD  ;
DR   Q3ATB5, FMT_CHLCH  ;  Q824Q3, FMT_CHLCV  ;  B3EE18, FMT_CHLL2  ;
DR   Q9PJL2, FMT_CHLMU  ;  B3EPG6, FMT_CHLPB  ;  A1BHJ9, FMT_CHLPD  ;
DR   Q9Z7Q5, FMT_CHLPN  ;  B9LFJ4, FMT_CHLSY  ;  B0B8A4, FMT_CHLT2  ;
DR   Q3KLG7, FMT_CHLTA  ;  B0B9Y3, FMT_CHLTB  ;  Q8KCG8, FMT_CHLTE  ;
DR   O84535, FMT_CHLTR  ;  Q1QTJ4, FMT_CHRSD  ;  Q7NQ76, FMT_CHRVO  ;
DR   A5CRW8, FMT_CLAM3  ;  B0REV2, FMT_CLAMS  ;  O05101, FMT_CLOAB  ;
DR   A6LSJ8, FMT_CLOB8  ;  B2V4B2, FMT_CLOBA  ;  B2THS2, FMT_CLOBB  ;
DR   B8I255, FMT_CLOCE  ;  Q182S2, FMT_CLOD6  ;  A0Q115, FMT_CLONN  ;
DR   Q8XJL3, FMT_CLOPE  ;  Q0SS78, FMT_CLOPS  ;  Q895Q1, FMT_CLOTE  ;
DR   A3DCX5, FMT_CLOTH  ;  Q48AS9, FMT_COLP3  ;  B5Y7I0, FMT_COPPD  ;
DR   C3PG27, FMT_CORA7  ;  Q6NH23, FMT_CORDI  ;  Q8FT52, FMT_COREF  ;
DR   A4QEH4, FMT_CORGB  ;  Q8NQ47, FMT_CORGL  ;  Q4JVI0, FMT_CORJK  ;
DR   B1VDP0, FMT_CORU7  ;  B6J655, FMT_COXB1  ;  B6J3C2, FMT_COXB2  ;
DR   A9KH14, FMT_COXBN  ;  A9N9H5, FMT_COXBR  ;  Q83AA8, FMT_COXBU  ;
DR   B8HUR2, FMT_CYAP4  ;  B7KHD0, FMT_CYAP7  ;  Q47K50, FMT_DECAR  ;
DR   Q3Z614, FMT_DEHE1  ;  A5FPB5, FMT_DEHSB  ;  Q3ZZW0, FMT_DEHSC  ;
DR   Q9RRQ3, FMT_DEIRA  ;  A9BS67, FMT_DELAS  ;  B8J1H5, FMT_DESDA  ;
DR   Q6AQ97, FMT_DESPS  ;  A4J579, FMT_DESRM  ;  Q725Q9, FMT_DESVH  ;
DR   A1V9B4, FMT_DESVV  ;  A5EWL9, FMT_DICNV  ;  B5YF45, FMT_DICT6  ;
DR   B8E0X6, FMT_DICTD  ;  A8LLC0, FMT_DINSH  ;  A7ZSH6, FMT_ECO24  ;
DR   B7UK11, FMT_ECO27  ;  B7MCQ3, FMT_ECO45  ;  B7LHY8, FMT_ECO55  ;
DR   Q8X8F1, FMT_ECO57  ;  B5YT07, FMT_ECO5E  ;  B7NLK7, FMT_ECO7I  ;
DR   B7N172, FMT_ECO81  ;  B7M0Z3, FMT_ECO8A  ;  C4ZUE2, FMT_ECOBW  ;
DR   B1X6E0, FMT_ECODH  ;  A8A592, FMT_ECOHS  ;  A1AGH9, FMT_ECOK1  ;
DR   Q0TCH4, FMT_ECOL5  ;  Q8FD13, FMT_ECOL6  ;  B1IQ12, FMT_ECOLC  ;
DR   P23882, FMT_ECOLI  ;  B7NDQ9, FMT_ECOLU  ;  B6I201, FMT_ECOSE  ;
DR   B1LGP4, FMT_ECOSM  ;  Q1R645, FMT_ECOUT  ;  C5BF18, FMT_EDWI9  ;
DR   Q3YSQ0, FMT_EHRCJ  ;  Q2GFU1, FMT_EHRCR  ;  Q5FFG4, FMT_EHRRG  ;
DR   Q5HBX2, FMT_EHRRW  ;  B2KCQ4, FMT_ELUMP  ;  A4WF96, FMT_ENT38  ;
DR   Q82ZD8, FMT_ENTFA  ;  A7MPE8, FMT_ENTS8  ;  Q6D001, FMT_ERWCT  ;
DR   B2VK94, FMT_ERWT9  ;  B7LRQ4, FMT_ESCF3  ;  C4Z520, FMT_EUBE2  ;
DR   C4ZEV8, FMT_EUBR3  ;  A7HLH4, FMT_FERNB  ;  B0S140, FMT_FINM2  ;
DR   A5FNN7, FMT_FLAJ1  ;  A6H148, FMT_FLAPJ  ;  Q0RF89, FMT_FRAAA  ;
DR   B0U0T8, FMT_FRAP2  ;  Q2J845, FMT_FRASC  ;  A8LE22, FMT_FRASN  ;
DR   Q14HS3, FMT_FRAT1  ;  A7NCY0, FMT_FRATF  ;  Q2A2U6, FMT_FRATH  ;
DR   B2SGG5, FMT_FRATM  ;  A0Q626, FMT_FRATN  ;  Q0BLC5, FMT_FRATO  ;
DR   Q5NGC1, FMT_FRATT  ;  A4IXN6, FMT_FRATW  ;  Q8RDM3, FMT_FUSNN  ;
DR   B5ED77, FMT_GEOBB  ;  Q5L0S3, FMT_GEOKA  ;  B3EAP0, FMT_GEOLS  ;
DR   Q39QC2, FMT_GEOMG  ;  B9M2D5, FMT_GEOSF  ;  Q74GW4, FMT_GEOSL  ;
DR   C5D8R6, FMT_GEOSW  ;  A4IM47, FMT_GEOTN  ;  A5GBL0, FMT_GEOUR  ;
DR   Q7NJK1, FMT_GLOVI  ;  A9HKQ4, FMT_GLUDA  ;  Q5FPX2, FMT_GLUOX  ;
DR   Q0BUB3, FMT_GRABC  ;  Q7VK98, FMT_HAEDU  ;  Q4QMV7, FMT_HAEI8  ;
DR   A5UEB3, FMT_HAEIE  ;  A5UH91, FMT_HAEIG  ;  P44787, FMT_HAEIN  ;
DR   B8F7U6, FMT_HAEPS  ;  Q0I182, FMT_HAES1  ;  B0UWZ4, FMT_HAES2  ;
DR   Q2SQX2, FMT_HAHCH  ;  A1WZH3, FMT_HALHL  ;  B8CWS7, FMT_HALOH  ;
DR   C4K6Y1, FMT_HAMD5  ;  Q17Y87, FMT_HELAH  ;  B0TGS9, FMT_HELMI  ;
DR   B6JMY1, FMT_HELP2  ;  Q1CSC6, FMT_HELPH  ;  Q9ZK72, FMT_HELPJ  ;
DR   P56461, FMT_HELPY  ;  A9B2Z9, FMT_HERA2  ;  A4G1G8, FMT_HERAR  ;
DR   Q96DP5, FMT_HUMAN  ;  B4U5Z8, FMT_HYDS0  ;  Q5QXI6, FMT_IDILO  ;
DR   A6SU87, FMT_JANMA  ;  Q28V76, FMT_JANSC  ;  A6WCA9, FMT_KINRD  ;
DR   B5XNC3, FMT_KLEP3  ;  A6TEU1, FMT_KLEP7  ;  C5CG19, FMT_KOSOT  ;
DR   Q5FJH5, FMT_LACAC  ;  Q03RS3, FMT_LACBA  ;  Q038H3, FMT_LACC3  ;
DR   B3WEW9, FMT_LACCB  ;  Q049P0, FMT_LACDB  ;  B2GD55, FMT_LACF3  ;
DR   Q044H0, FMT_LACGA  ;  Q74IM9, FMT_LACJO  ;  Q9CEE9, FMT_LACLA  ;
DR   A2RN27, FMT_LACLM  ;  Q02WP8, FMT_LACLS  ;  Q88WL3, FMT_LACPL  ;
DR   Q1WUB1, FMT_LACS1  ;  Q38XT6, FMT_LACSS  ;  Q5X1U6, FMT_LEGPA  ;
DR   A5IAY3, FMT_LEGPC  ;  Q5ZSC5, FMT_LEGPH  ;  Q5WTK7, FMT_LEGPL  ;
DR   Q6AF77, FMT_LEIXX  ;  Q04SV8, FMT_LEPBJ  ;  Q050Y2, FMT_LEPBL  ;
DR   B1XW99, FMT_LEPCP  ;  Q72S34, FMT_LEPIC  ;  Q8F3K6, FMT_LEPIN  ;
DR   Q92AI5, FMT_LISIN  ;  C1KWC2, FMT_LISMC  ;  Q71YJ3, FMT_LISMF  ;
DR   B8DDS9, FMT_LISMH  ;  Q8Y676, FMT_LISMO  ;  A0AJS8, FMT_LISW6  ;
DR   B1HQE4, FMT_LYSSC  ;  B9EB94, FMT_MACCJ  ;  Q2WAS9, FMT_MAGSA  ;
DR   A0L3X7, FMT_MAGSM  ;  Q65QF1, FMT_MANSM  ;  A1TWN0, FMT_MARAV  ;
DR   Q6F155, FMT_MESFL  ;  Q11LC8, FMT_MESSB  ;  Q603G2, FMT_METCA  ;
DR   Q1H4Y0, FMT_METFK  ;  B3DXI7, FMT_METI4  ;  B8IFQ3, FMT_METNO  ;
DR   A2SCF7, FMT_METPP  ;  B0UP41, FMT_METS4  ;  B0JY70, FMT_MICAN  ;
DR   Q2RK24, FMT_MOOTA  ;  Q9D799, FMT_MOUSE  ;  A0QI16, FMT_MYCA1  ;
DR   B1MCB9, FMT_MYCA9  ;  P64135, FMT_MYCBO  ;  A1KIJ5, FMT_MYCBP  ;
DR   C1AN51, FMT_MYCBT  ;  Q2SRX1, FMT_MYCCT  ;  P47605, FMT_MYCGE  ;
DR   A4TC02, FMT_MYCGI  ;  B8ZUM6, FMT_MYCLB  ;  Q9CCQ0, FMT_MYCLE  ;
DR   B2HP60, FMT_MYCMM  ;  Q6MTF8, FMT_MYCMS  ;  Q741F8, FMT_MYCPA  ;
DR   Q8EX00, FMT_MYCPE  ;  P75235, FMT_MYCPN  ;  Q98RG4, FMT_MYCPU  ;
DR   A0QWU2, FMT_MYCS2  ;  A3PZ81, FMT_MYCSJ  ;  A1UFM0, FMT_MYCSK  ;
DR   Q1B9E3, FMT_MYCSS  ;  A5U2A8, FMT_MYCTA  ;  P64134, FMT_MYCTU  ;
DR   A0PPK9, FMT_MYCUA  ;  A1T8J4, FMT_MYCVP  ;  Q1DCG7, FMT_MYXXD  ;
DR   B2A2K2, FMT_NATTJ  ;  Q5F5P7, FMT_NEIG1  ;  B4RPX5, FMT_NEIG2  ;
DR   A9M463, FMT_NEIM0  ;  Q9JWY9, FMT_NEIMA  ;  Q9K1K6, FMT_NEIMB  ;
DR   A1KRE6, FMT_NEIMF  ;  Q0AJ02, FMT_NITEC  ;  Q820J7, FMT_NITEU  ;
DR   Q1QH77, FMT_NITHX  ;  Q2YC20, FMT_NITMU  ;  Q3J6T9, FMT_NITOC  ;
DR   A6Q4C9, FMT_NITSB  ;  Q3SN28, FMT_NITWN  ;  Q5YTN5, FMT_NOCFA  ;
DR   A1SJG2, FMT_NOCSJ  ;  Q8YRI6, FMT_NOSS1  ;  Q2G493, FMT_NOVAD  ;
DR   Q8ER25, FMT_OCEIH  ;  A6WYK8, FMT_OCHA4  ;  B6JJP7, FMT_OLICO  ;
DR   A5CF64, FMT_ORITB  ;  A6LCS5, FMT_PARD8  ;  A1AZR0, FMT_PARDP  ;
DR   A7HPQ2, FMT_PARL1  ;  Q6ME71, FMT_PARUW  ;  P57949, FMT_PASMU  ;
DR   C6DFR6, FMT_PECCP  ;  Q03FY3, FMT_PEDPA  ;  Q3B2V0, FMT_PELLD  ;
DR   A1ALC4, FMT_PELPD  ;  A5D1B9, FMT_PELTS  ;  Q4FNG0, FMT_PELUB  ;
DR   C0QUK8, FMT_PERMH  ;  B4RDU2, FMT_PHEZH  ;  Q7MYI1, FMT_PHOLL  ;
DR   Q6LLJ2, FMT_PHOPR  ;  A1VU45, FMT_POLNA  ;  B1XSN1, FMT_POLNS  ;
DR   A4T0M5, FMT_POLSQ  ;  B2RM92, FMT_PORG3  ;  Q7MTE3, FMT_PORGI  ;
DR   B4S9B8, FMT_PROA2  ;  Q6A8H1, FMT_PROAC  ;  A2C296, FMT_PROM1  ;
DR   A8G4Z4, FMT_PROM2  ;  A2C9M6, FMT_PROM3  ;  A9BAJ3, FMT_PROM4  ;
DR   A2BWG3, FMT_PROM5  ;  Q31AS6, FMT_PROM9  ;  Q7VBU5, FMT_PROMA  ;
DR   B4F1L6, FMT_PROMH  ;  Q7V7H4, FMT_PROMM  ;  Q7TUA3, FMT_PROMP  ;
DR   A2BRA1, FMT_PROMS  ;  Q46KX0, FMT_PROMT  ;  A4SFP1, FMT_PROVI  ;
DR   Q48QI2, FMT_PSE14  ;  Q15ZY3, FMT_PSEA6  ;  A6UX80, FMT_PSEA7  ;
DR   B7V0Q3, FMT_PSEA8  ;  Q02V63, FMT_PSEAB  ;  O85732, FMT_PSEAE  ;
DR   Q1IH35, FMT_PSEE4  ;  Q4KKR0, FMT_PSEF5  ;  C3KE47, FMT_PSEFS  ;
DR   Q3IDI3, FMT_PSEHT  ;  A4XNB2, FMT_PSEMY  ;  A5VWJ8, FMT_PSEP1  ;
DR   Q3KKE6, FMT_PSEPF  ;  B0KF29, FMT_PSEPG  ;  Q88RR2, FMT_PSEPK  ;
DR   B1J432, FMT_PSEPW  ;  Q88B42, FMT_PSESM  ;  Q500T0, FMT_PSEU2  ;
DR   A4VFH7, FMT_PSEU5  ;  A1SR38, FMT_PSYIN  ;  B2U795, FMT_RALPJ  ;
DR   Q8Y3A8, FMT_RALSO  ;  Q5I0C5, FMT_RAT    ;  A9WR74, FMT_RENSM  ;
DR   B3PZF7, FMT_RHIE6  ;  Q2KD50, FMT_RHIEC  ;  Q98D53, FMT_RHILO  ;
DR   B5ZN20, FMT_RHILW  ;  Q92SH5, FMT_RHIME  ;  C3MF25, FMT_RHISN  ;
DR   Q7UHZ6, FMT_RHOBA  ;  B6IPI1, FMT_RHOCS  ;  C0ZZD9, FMT_RHOE4  ;
DR   Q21RP5, FMT_RHOFD  ;  C1B4K2, FMT_RHOOB  ;  Q2J2C5, FMT_RHOP2  ;
DR   Q6NC50, FMT_RHOPA  ;  Q21B59, FMT_RHOPB  ;  Q13F19, FMT_RHOPS  ;
DR   B3QCH2, FMT_RHOPT  ;  A3PMS1, FMT_RHOS1  ;  Q3IZH6, FMT_RHOS4  ;
DR   A4WNU8, FMT_RHOS5  ;  B9KML7, FMT_RHOSK  ;  C3PMQ0, FMT_RICAE  ;
DR   O33509, FMT_RICAK  ;  O33508, FMT_RICAM  ;  O33510, FMT_RICAU  ;
DR   Q1RJ22, FMT_RICBR  ;  O33520, FMT_RICCK  ;  O33519, FMT_RICCN  ;
DR   O33523, FMT_RICFE  ;  A8F0W5, FMT_RICM5  ;  O33535, FMT_RICMO  ;
DR   O33543, FMT_RICPA  ;  P50932, FMT_RICPR  ;  C4K0Y8, FMT_RICPU  ;
DR   O33545, FMT_RICRH  ;  O33544, FMT_RICRI  ;  B0BWL1, FMT_RICRO  ;
DR   O33575, FMT_RICSI  ;  O33582, FMT_RICTY  ;  A7NNY4, FMT_ROSCS  ;
DR   Q16AL2, FMT_ROSDO  ;  A5V070, FMT_ROSS1  ;  Q1AVZ9, FMT_RUBXD  ;
DR   A4FBJ4, FMT_SACEN  ;  B5F7R4, FMT_SALA4  ;  A8LY30, FMT_SALAI  ;
DR   Q57J63, FMT_SALCH  ;  B5FJI3, FMT_SALDC  ;  B5R1E4, FMT_SALEP  ;
DR   B5RH48, FMT_SALG2  ;  B4TJX8, FMT_SALHS  ;  B4SUQ9, FMT_SALNS  ;
DR   Q5PIT7, FMT_SALPA  ;  A9N8B2, FMT_SALPB  ;  C0PZV0, FMT_SALPC  ;
DR   B5BGV4, FMT_SALPK  ;  B4TXB1, FMT_SALSV  ;  Q8Z1X0, FMT_SALTI  ;
DR   A4X631, FMT_SALTO  ;  Q8ZLM6, FMT_SALTY  ;  Q9UTG6, FMT_SCHPO  ;
DR   A8GKG6, FMT_SERP5  ;  A1S1J8, FMT_SHEAM  ;  B8E3S3, FMT_SHEB2  ;
DR   A3CYK4, FMT_SHEB5  ;  A6WHB0, FMT_SHEB8  ;  A9KUA1, FMT_SHEB9  ;
DR   Q12TA6, FMT_SHEDO  ;  Q08A29, FMT_SHEFN  ;  B0TLC9, FMT_SHEHH  ;
DR   A3QJF5, FMT_SHELP  ;  Q8EKQ9, FMT_SHEON  ;  A8GYH2, FMT_SHEPA  ;
DR   A4Y1C6, FMT_SHEPC  ;  B8CHB1, FMT_SHEPW  ;  A0KR60, FMT_SHESA  ;
DR   A8FP74, FMT_SHESH  ;  Q0HPA7, FMT_SHESM  ;  Q0I0S3, FMT_SHESR  ;
DR   A1RDX6, FMT_SHESW  ;  B1KCW3, FMT_SHEWM  ;  B2U2Q5, FMT_SHIB3  ;
DR   Q31VY9, FMT_SHIBS  ;  Q32B62, FMT_SHIDS  ;  Q0T015, FMT_SHIF8  ;
DR   Q83PZ0, FMT_SHIFL  ;  Q3YWX2, FMT_SHISS  ;  Q5LNI8, FMT_SILPO  ;
DR   Q1GDF7, FMT_SILST  ;  A6U5I5, FMT_SINMW  ;  Q2NQQ3, FMT_SODGM  ;
DR   Q023V5, FMT_SOLUE  ;  A9FL08, FMT_SORC5  ;  Q1GWK0, FMT_SPHAL  ;
DR   A5VDM0, FMT_SPHWW  ;  A7X1H4, FMT_STAA1  ;  A6U135, FMT_STAA2  ;
DR   Q2FHM2, FMT_STAA3  ;  Q2FZ68, FMT_STAA8  ;  A5ISA1, FMT_STAA9  ;
DR   Q2YXK0, FMT_STAAB  ;  Q5HGL6, FMT_STAAC  ;  A6QGB6, FMT_STAAE  ;
DR   P64136, FMT_STAAM  ;  P99127, FMT_STAAN  ;  Q6GHL9, FMT_STAAR  ;
DR   Q6G9Z7, FMT_STAAS  ;  A8Z3Q2, FMT_STAAT  ;  Q8NX18, FMT_STAAW  ;
DR   B9DPM5, FMT_STACT  ;  Q5HPX5, FMT_STAEQ  ;  Q8CSW1, FMT_STAES  ;
DR   Q3K365, FMT_STRA1  ;  P64137, FMT_STRA3  ;  P64138, FMT_STRA5  ;
DR   Q827P7, FMT_STRAW  ;  Q9L0Y6, FMT_STRCO  ;  C0M780, FMT_STRE4  ;
DR   A8AVV3, FMT_STRGC  ;  B1W473, FMT_STRGG  ;  B4SKH6, FMT_STRM5  ;
DR   B2FIR3, FMT_STRMK  ;  Q8DVK4, FMT_STRMU  ;  Q99YM7, FMT_STRP1  ;
DR   Q04J40, FMT_STRP2  ;  P0DB04, FMT_STRP3  ;  B5E782, FMT_STRP4  ;
DR   Q5XAP4, FMT_STRP6  ;  C1C8X2, FMT_STRP7  ;  Q8P003, FMT_STRP8  ;
DR   Q1JAJ7, FMT_STRPB  ;  Q1JKP9, FMT_STRPC  ;  Q1JFP0, FMT_STRPD  ;
DR   Q1J5I9, FMT_STRPF  ;  A2RD70, FMT_STRPG  ;  B1I7J8, FMT_STRPI  ;
DR   B8ZMJ8, FMT_STRPJ  ;  Q48S21, FMT_STRPM  ;  Q97PA6, FMT_STRPN  ;
DR   P0DB05, FMT_STRPQ  ;  B2IS85, FMT_STRPS  ;  B5XMI3, FMT_STRPZ  ;
DR   Q8DNR7, FMT_STRR6  ;  A4VZN1, FMT_STRS2  ;  C0MH30, FMT_STRS7  ;
DR   A3CPX4, FMT_STRSV  ;  A4VTF3, FMT_STRSY  ;  Q5LYX4, FMT_STRT1  ;
DR   Q5M3I7, FMT_STRT2  ;  B9DV45, FMT_STRU0  ;  C1CFV7, FMT_STRZJ  ;
DR   C1CM71, FMT_STRZP  ;  C1CSZ4, FMT_STRZT  ;  Q30QP2, FMT_SULDN  ;
DR   A6QB68, FMT_SULNB  ;  B2V969, FMT_SULSY  ;  Q67PR4, FMT_SYMTH  ;
DR   Q2LRX4, FMT_SYNAS  ;  Q31LC9, FMT_SYNE7  ;  Q2JTY2, FMT_SYNJA  ;
DR   Q2JK54, FMT_SYNJB  ;  B1XP50, FMT_SYNP2  ;  Q5N0J8, FMT_SYNP6  ;
DR   A5GKR0, FMT_SYNPW  ;  Q7U6Z1, FMT_SYNPX  ;  A5GU17, FMT_SYNR3  ;
DR   Q0IAL3, FMT_SYNS3  ;  Q3AXQ4, FMT_SYNS9  ;  Q3AK21, FMT_SYNSC  ;
DR   Q0AXL4, FMT_SYNWW  ;  Q55163, FMT_SYNY3  ;  B7IFU7, FMT_THEAB  ;
DR   Q8DHS1, FMT_THEEB  ;  Q47R04, FMT_THEFY  ;  A8F525, FMT_THELT  ;
DR   A6LJK9, FMT_THEM4  ;  Q9WYZ8, FMT_THEMA  ;  B9KBC2, FMT_THENN  ;
DR   A5IJP6, FMT_THEP1  ;  B1L8W7, FMT_THESQ  ;  Q72H32, FMT_THET2  ;
DR   Q5SLH3, FMT_THET8  ;  P43523, FMT_THETH  ;  Q8R9T1, FMT_THETN  ;
DR   B5YIL6, FMT_THEYD  ;  Q31J85, FMT_THICR  ;  Q3SMS3, FMT_THIDA  ;
DR   C4L7Y3, FMT_TOLAT  ;  Q73M65, FMT_TREDE  ;  O83737, FMT_TREPA  ;
DR   B2S3Z5, FMT_TREPS  ;  Q114P5, FMT_TRIEI  ;  B1GZ11, FMT_UNCTG  ;
DR   B1AJA4, FMT_UREP2  ;  Q9PQ27, FMT_UREPA  ;  B5ZBV9, FMT_UREU1  ;
DR   C5CQE1, FMT_VARPS  ;  A1WQ79, FMT_VEREI  ;  O87726, FMT_VIBAL  ;
DR   A5F4B4, FMT_VIBC3  ;  Q9KVU4, FMT_VIBCH  ;  C3LPB8, FMT_VIBCM  ;
DR   Q5E1Q7, FMT_VIBF1  ;  B5FCW7, FMT_VIBFM  ;  A7N122, FMT_VIBHB  ;
DR   Q87KD4, FMT_VIBPA  ;  B7VMX2, FMT_VIBSL  ;  Q8DDE4, FMT_VIBVU  ;
DR   Q7MGK5, FMT_VIBVY  ;  Q8D259, FMT_WIGBR  ;  Q73GR6, FMT_WOLPM  ;
DR   B3CLK1, FMT_WOLPP  ;  Q7MA26, FMT_WOLSU  ;  C0R3S7, FMT_WOLWR  ;
DR   Q8PG21, FMT_XANAC  ;  Q3BNK7, FMT_XANC5  ;  Q4UQ15, FMT_XANC8  ;
DR   Q8P4G0, FMT_XANCP  ;  Q2P825, FMT_XANOM  ;  B2SL54, FMT_XANOP  ;
DR   Q5H5D0, FMT_XANOR  ;  B2I8S3, FMT_XYLF2  ;  Q9PEV1, FMT_XYLFA  ;
DR   B0U4M3, FMT_XYLFM  ;  Q87AR0, FMT_XYLFT  ;  P32785, FMT_YEAST  ;
DR   A1JRZ2, FMT_YERE8  ;  A7FNK3, FMT_YERP3  ;  Q1C2X8, FMT_YERPA  ;
DR   B2K505, FMT_YERPB  ;  Q8ZJ80, FMT_YERPE  ;  A9R926, FMT_YERPG  ;
DR   Q1CCX5, FMT_YERPN  ;  A4TH22, FMT_YERPP  ;  Q664V3, FMT_YERPS  ;
DR   B1JJH7, FMT_YERPY  ;  Q5NPC5, FMT_ZYMMO  ;
//
ID   2.1.2.10
DE   Aminomethyltransferase.
AN   Glycine synthase.
AN   Glycine-cleavage system T-protein.
AN   Tetrahydrofolate aminomethyltransferase.
CA   [Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate =
CA   [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH(3).
CC   -!- A component, with EC 1.4.4.2 and EC 1.8.1.4, of the glycine cleavage
CC       system, formerly known as glycine synthase.
CC   -!- The glycine cleavage system is composed of four components that only
CC       loosely associate: the P protein (EC 1.4.4.2), the T protein
CC       (EC 2.1.2.10), the L protein (EC 1.8.1.4) and the lipoyl-bearing H
CC       protein.
DR   Q1INT8, GCST_ACIBL ;  C1F933, GCST_ACIC5 ;  A0KJ03, GCST_AERHH ;
DR   Q9YBA2, GCST_AERPE ;  A4SP35, GCST_AERS4 ;  Q0VLA6, GCST_ALCBS ;
DR   A6TMY6, GCST_ALKMQ ;  A8MEG4, GCST_ALKOO ;  B4RSJ5, GCST_ALTMD ;
DR   B7GH71, GCST_ANOFW ;  O67441, GCST_AQUAE ;  O65396, GCST_ARATH ;
DR   A7Z6M4, GCST_BACA2 ;  C3P8D5, GCST_BACAA ;  C3LKQ4, GCST_BACAC ;
DR   A0RIL1, GCST_BACAH ;  Q81M06, GCST_BACAN ;  B7JMV1, GCST_BACC0 ;
DR   Q730W1, GCST_BACC1 ;  B7IXL4, GCST_BACC2 ;  C1ERV0, GCST_BACC3 ;
DR   B7HBA0, GCST_BACC4 ;  B7HNZ1, GCST_BACC7 ;  A7GSN8, GCST_BACCN ;
DR   B9IXL9, GCST_BACCQ ;  Q818M3, GCST_BACCR ;  Q634V6, GCST_BACCZ ;
DR   Q5LFT6, GCST_BACFN ;  Q64WS3, GCST_BACFR ;  Q9K934, GCST_BACHD ;
DR   Q6HDT6, GCST_BACHK ;  Q65HF9, GCST_BACLD ;  A8FF41, GCST_BACP2 ;
DR   Q5WF30, GCST_BACSK ;  P54378, GCST_BACSU ;  Q89YZ6, GCST_BACTN ;
DR   A6L6X5, GCST_BACV8 ;  A9VH12, GCST_BACWK ;  Q6MQ03, GCST_BDEBA ;
DR   Q2KYM2, GCST_BORA1 ;  Q7WP31, GCST_BORBR ;  Q7W1C6, GCST_BORPA ;
DR   A9I7L6, GCST_BORPD ;  Q7W0E5, GCST_BORPE ;  P25285, GCST_BOVIN ;
DR   B1YQQ3, GCST_BURA4 ;  B1JSZ4, GCST_BURCC ;  B4EF28, GCST_BURCJ ;
DR   A9ACU5, GCST_BURM1 ;  A3MQP5, GCST_BURM7 ;  A2S6F4, GCST_BURM9 ;
DR   Q62FM9, GCST_BURMA ;  A3P0U5, GCST_BURP0 ;  A3NEZ8, GCST_BURP6 ;
DR   B2JJ71, GCST_BURP8 ;  Q63PL4, GCST_BURPS ;  Q39KT9, GCST_BURS3 ;
DR   A4JA71, GCST_BURVG ;  Q9TSZ7, GCST_CANFA ;  Q3AET7, GCST_CARHZ ;
DR   B3PI82, GCST_CELJU ;  P28337, GCST_CHICK ;  Q3AQ17, GCST_CHLCH ;
DR   B3EFX7, GCST_CHLL2 ;  B3QLF1, GCST_CHLP8 ;  A1BI02, GCST_CHLPD ;
DR   B3QV24, GCST_CHLT3 ;  Q8KBJ9, GCST_CHLTE ;  Q7NSJ3, GCST_CHRVO ;
DR   A8APB4, GCST_CITK8 ;  A7FRV3, GCST_CLOB1 ;  C3L1M5, GCST_CLOB6 ;
DR   C1FTW3, GCST_CLOBJ ;  B1IEV3, GCST_CLOBK ;  A7GB83, GCST_CLOBL ;
DR   B1KWD5, GCST_CLOBM ;  Q486J8, GCST_COLP3 ;  C3PHK3, GCST_CORA7 ;
DR   Q4JXU5, GCST_CORJK ;  Q83B06, GCST_COXBU ;  Q0K5P5, GCST_CUPNH ;
DR   Q46VZ7, GCST_CUPPJ ;  B3R7J7, GCST_CUPTR ;  B7K468, GCST_CYAP8 ;
DR   Q47D83, GCST_DECAR ;  C1D0F7, GCST_DEIDV ;  B8FT33, GCST_DESHD ;
DR   Q24TH3, GCST_DESHY ;  A4J2F6, GCST_DESRM ;  Q54DD3, GCST_DICDI ;
DR   A7ZR14, GCST_ECO24 ;  B7UHV3, GCST_ECO27 ;  B7MM91, GCST_ECO45 ;
DR   B7LF91, GCST_ECO55 ;  Q8XD32, GCST_ECO57 ;  B5YQ97, GCST_ECO5E ;
DR   B7NHW6, GCST_ECO7I ;  B7MZ57, GCST_ECO81 ;  B7LYG9, GCST_ECO8A ;
DR   C5A0H7, GCST_ECOBW ;  A8A446, GCST_ECOHS ;  Q8FE65, GCST_ECOL6 ;
DR   B1IT97, GCST_ECOLC ;  P27248, GCST_ECOLI ;  B7N7E8, GCST_ECOLU ;
DR   B6I738, GCST_ECOSE ;  B1LDA5, GCST_ECOSM ;  Q1R7C6, GCST_ECOUT ;
DR   C5BAT2, GCST_EDWI9 ;  A4WE57, GCST_ENT38 ;  A7MR82, GCST_ENTS8 ;
DR   Q6D976, GCST_ERWCT ;  B2VF35, GCST_ERWT9 ;  B7LPB9, GCST_ESCF3 ;
DR   B1YLN6, GCST_EXIS2 ;  O49849, GCST_FLAAN ;  A6GXW3, GCST_FLAPJ ;
DR   P49363, GCST_FLAPR ;  O23936, GCST_FLATR ;  Q0RFF6, GCST_FRAAA ;
DR   B0TZJ8, GCST_FRAP2 ;  A8LFB7, GCST_FRASN ;  Q14J42, GCST_FRAT1 ;
DR   A7NAH6, GCST_FRATF ;  Q2A4V3, GCST_FRATH ;  B2SFM1, GCST_FRATM ;
DR   A0Q585, GCST_FRATN ;  Q0BN73, GCST_FRATO ;  Q5NHP0, GCST_FRATT ;
DR   A4IZK8, GCST_FRATW ;  Q5KX76, GCST_GEOKA ;  C5D4A2, GCST_GEOSW ;
DR   A4IQV5, GCST_GEOTN ;  Q7NFJ5, GCST_GLOVI ;  A1WWA3, GCST_HALHL ;
DR   Q5V230, GCST_HALMA ;  B8D1D7, GCST_HALOH ;  B0R5Y8, GCST_HALS3 ;
DR   Q9HPJ7, GCST_HALSA ;  A9B2Q5, GCST_HERA2 ;  P48728, GCST_HUMAN ;
DR   Q5QVA8, GCST_IDILO ;  A6TDR7, GCST_KLEP7 ;  Q5X8W1, GCST_LEGPA ;
DR   A5I9T7, GCST_LEGPC ;  Q5ZZ93, GCST_LEGPH ;  Q5X0A4, GCST_LEGPL ;
DR   B0SGN8, GCST_LEPBA ;  Q04PM9, GCST_LEPBJ ;  Q055P6, GCST_LEPBL ;
DR   B0SQA1, GCST_LEPBP ;  Q72VI6, GCST_LEPIC ;  Q8F935, GCST_LEPIN ;
DR   Q92C06, GCST_LISIN ;  C1L2Q4, GCST_LISMC ;  Q71ZX4, GCST_LISMF ;
DR   B8DFY0, GCST_LISMH ;  Q8Y7D5, GCST_LISMO ;  A0AIE9, GCST_LISW6 ;
DR   B1HSN7, GCST_LYSSC ;  P93256, GCST_MESCR ;  Q60BW3, GCST_METCA ;
DR   Q2RH46, GCST_MOOTA ;  Q8CFA2, GCST_MOUSE ;  A0QEZ6, GCST_MYCA1 ;
DR   P64221, GCST_MYCBO ;  B8ZQK6, GCST_MYCLB ;  O32955, GCST_MYCLE ;
DR   Q73YK4, GCST_MYCPA ;  P64220, GCST_MYCTU ;  A0PTP8, GCST_MYCUA ;
DR   Q3IN28, GCST_NATPD ;  B2A2T4, GCST_NATTJ ;  Q9JVP2, GCST_NEIMA ;
DR   Q9K0L8, GCST_NEIMB ;  Q0AEP7, GCST_NITEC ;  Q82WQ6, GCST_NITEU ;
DR   Q3JDS3, GCST_NITOC ;  Q5YZ49, GCST_NOCFA ;  Q8YNF7, GCST_NOSS1 ;
DR   Q8CXD9, GCST_OCEIH ;  A6L8T3, GCST_PARD8 ;  P49364, GCST_PEA   ;
DR   C6D8W9, GCST_PECCP ;  Q3B5U7, GCST_PELLD ;  B4SED4, GCST_PELPB ;
DR   Q7N197, GCST_PHOLL ;  B2RI74, GCST_PORG3 ;  Q7MUG4, GCST_PORGI ;
DR   B4S437, GCST_PROA2 ;  Q6A9R6, GCST_PROAC ;  A3PFH6, GCST_PROM0 ;
DR   A2C5F7, GCST_PROM1 ;  A8G7J2, GCST_PROM2 ;  A2CDX3, GCST_PROM3 ;
DR   A2BZ74, GCST_PROM5 ;  Q7V9I2, GCST_PROMA ;  B4F0N9, GCST_PROMH ;
DR   Q7TUI6, GCST_PROMM ;  Q7TU18, GCST_PROMP ;  A2BTR9, GCST_PROMS ;
DR   Q46I99, GCST_PROMT ;  A4SDB4, GCST_PROVI ;  Q15PU4, GCST_PSEA6 ;
DR   Q9HTX5, GCST_PSEAE ;  Q3IFV9, GCST_PSEHT ;  Q88CI7, GCST_PSEPK ;
DR   Q88AS0, GCST_PSESM ;  Q9UZP8, GCST_PYRAB ;  Q8U185, GCST_PYRFU ;
DR   O58888, GCST_PYRHO ;  Q5JDG3, GCST_PYRKO ;  Q1LHM4, GCST_RALME ;
DR   B2UG80, GCST_RALPJ ;  Q8XUA0, GCST_RALSO ;  Q1AR89, GCST_RUBXD ;
DR   Q21NX7, GCST_SACD2 ;  A4FLG1, GCST_SACEN ;  B5F5I0, GCST_SALA4 ;
DR   A9MRH0, GCST_SALAR ;  Q57K60, GCST_SALCH ;  B5FUG8, GCST_SALDC ;
DR   B5QXI2, GCST_SALEP ;  B5RE16, GCST_SALG2 ;  B4TGX5, GCST_SALHS ;
DR   B4T550, GCST_SALNS ;  Q5PJG4, GCST_SALPA ;  A9N3N3, GCST_SALPB ;
DR   C0PY28, GCST_SALPC ;  B5BFM0, GCST_SALPK ;  B4TV24, GCST_SALSV ;
DR   P64223, GCST_SALTI ;  P64222, GCST_SALTY ;  O14110, GCST_SCHPO ;
DR   A8GIS1, GCST_SERP5 ;  A1S967, GCST_SHEAM ;  B8EB47, GCST_SHEB2 ;
DR   A3D083, GCST_SHEB5 ;  A6WSL3, GCST_SHEB8 ;  A9L332, GCST_SHEB9 ;
DR   Q12R04, GCST_SHEDO ;  Q07YC7, GCST_SHEFN ;  B0TSG7, GCST_SHEHH ;
DR   A3QHI2, GCST_SHELP ;  Q8EIQ8, GCST_SHEON ;  A8H7T1, GCST_SHEPA ;
DR   A4YAE0, GCST_SHEPC ;  B8CK16, GCST_SHEPW ;  A0L105, GCST_SHESA ;
DR   A8FZK6, GCST_SHESH ;  Q0HEX0, GCST_SHESM ;  Q0HZ30, GCST_SHESR ;
DR   A1RFY6, GCST_SHESW ;  B1KG89, GCST_SHEWM ;  B2U0S2, GCST_SHIB3 ;
DR   Q31WG6, GCST_SHIBS ;  Q32BW7, GCST_SHIDS ;  Q0T0Z3, GCST_SHIF8 ;
DR   Q83JU1, GCST_SHIFL ;  Q3YXW5, GCST_SHISS ;  Q2NRE8, GCST_SODGM ;
DR   P54260, GCST_SOLTU ;  A7X2S3, GCST_STAA1 ;  A6U208, GCST_STAA2 ;
DR   Q2FGI5, GCST_STAA3 ;  Q2FY33, GCST_STAA8 ;  A5IT65, GCST_STAA9 ;
DR   Q2YSZ2, GCST_STAAB ;  Q5HFM2, GCST_STAAC ;  A6QH81, GCST_STAAE ;
DR   P64224, GCST_STAAM ;  P64225, GCST_STAAN ;  Q6GGG2, GCST_STAAR ;
DR   Q6G929, GCST_STAAS ;  A8Z476, GCST_STAAT ;  P64226, GCST_STAAW ;
DR   B9DNN7, GCST_STACT ;  Q5HP12, GCST_STAEQ ;  Q8CSF4, GCST_STAES ;
DR   Q4L6N7, GCST_STAHJ ;  Q49XY1, GCST_STAS1 ;  Q82JI2, GCST_STRAW ;
DR   O86567, GCST_STRCO ;  B4SSE0, GCST_STRM5 ;  B2FR21, GCST_STRMK ;
DR   Q67N36, GCST_SYMTH ;  Q31KT1, GCST_SYNE7 ;  B1XP99, GCST_SYNP2 ;
DR   Q5N136, GCST_SYNP6 ;  A5GPL8, GCST_SYNPW ;  Q7TTS1, GCST_SYNPX ;
DR   A5GWT1, GCST_SYNR3 ;  Q0I682, GCST_SYNS3 ;  Q3AVT0, GCST_SYNS9 ;
DR   P54261, GCST_SYNY3 ;  C5BM95, GCST_TERTT ;  Q8DKV6, GCST_THEEB ;
DR   C5A3P0, GCST_THEGJ ;  A8F8M9, GCST_THELT ;  A6LP67, GCST_THEM4 ;
DR   Q9WY54, GCST_THEMA ;  B9K6R7, GCST_THENN ;  B6YY21, GCST_THEON ;
DR   A5IKL0, GCST_THEP1 ;  B0KD95, GCST_THEP3 ;  B0K242, GCST_THEPX ;
DR   B1L9U1, GCST_THESQ ;  Q72LB1, GCST_THET2 ;  Q5SKX0, GCST_THET8 ;
DR   Q8RCV9, GCST_THETN ;  B8GNE2, GCST_THISH ;  Q8PI37, GCST_XANAC ;
DR   Q3BQN6, GCST_XANC5 ;  Q4UXC2, GCST_XANC8 ;  Q8P6T8, GCST_XANCP ;
DR   Q2P4S5, GCST_XANOM ;  B2SSQ1, GCST_XANOP ;  Q5H1X3, GCST_XANOR ;
DR   B2I6Q1, GCST_XYLF2 ;  Q9PGW5, GCST_XYLFA ;  B0U270, GCST_XYLFM ;
DR   Q87EZ6, GCST_XYLFT ;  P48015, GCST_YEAST ;  A1JPN6, GCST_YERE8 ;
DR   A7FF19, GCST_YERP3 ;  Q1CB44, GCST_YERPA ;  B2K0Q5, GCST_YERPB ;
DR   Q8ZHI6, GCST_YERPE ;  A9R4K6, GCST_YERPG ;  Q1CEZ7, GCST_YERPN ;
DR   A4TIA5, GCST_YERPP ;  Q666R5, GCST_YERPS ;  B1JNS6, GCST_YERPY ;
//
ID   2.1.2.11
DE   3-methyl-2-oxobutanoate hydroxymethyltransferase.
AN   Alpha-ketoisovalerate hydroxymethyltransferase.
AN   Dehydropantoate hydroxymethyltransferase.
AN   Ketopantoate hydroxymethyltransferase.
CA   5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate + H(2)O =
CA   tetrahydrofolate + 2-dehydropantoate.
DR   Q89TZ6, PANB1_BRAJA;  A0K4T1, PANB1_BURCH;  Q0BI15, PANB1_BURCM;
DR   Q391N3, PANB1_BURS3;  Q2SNS0, PANB1_HAHCH;  A2SDV6, PANB1_METPP;
DR   Q02K83, PANB1_PSEAB;  Q9I3C3, PANB1_PSEAE;  Q1I9K4, PANB1_PSEE4;
DR   Q4K629, PANB1_PSEF5;  Q5E2T2, PANB1_VIBF1;  Q5NL34, PANB1_ZYMMO;
DR   Q9AMS0, PANB2_BRAJA;  A0AXR0, PANB2_BURCH;  Q0B4Z6, PANB2_BURCM;
DR   Q39JC5, PANB2_BURS3;  Q2S8W3, PANB2_HAHCH;  A2SEX8, PANB2_METPP;
DR   Q02FU3, PANB2_PSEAB;  Q9HV70, PANB2_PSEAE;  Q1I4P2, PANB2_PSEE4;
DR   Q4K5Y4, PANB2_PSEF5;  Q5DZU8, PANB2_VIBF1;  Q5NL16, PANB2_ZYMMO;
DR   Q89MZ4, PANB3_BRAJA;  B0BYP7, PANB_ACAM1 ;  A1TTV9, PANB_ACIAC ;
DR   Q6F854, PANB_ACIAD ;  B7H011, PANB_ACIB3 ;  B7I682, PANB_ACIB5 ;
DR   B2HTG4, PANB_ACIBC ;  Q1IHA5, PANB_ACIBL ;  B0VKK4, PANB_ACIBS ;
DR   B0V5M5, PANB_ACIBY ;  A0LTD0, PANB_ACIC1 ;  B7JBM8, PANB_ACIF2 ;
DR   B5ES07, PANB_ACIF5 ;  A1WBI7, PANB_ACISJ ;  A0KP07, PANB_AERHH ;
DR   Q9YE97, PANB_AERPE ;  A4SJ61, PANB_AERS4 ;  B9JH27, PANB_AGRRK ;
DR   Q8UA91, PANB_AGRT5 ;  B9JXS3, PANB_AGRVS ;  Q0VSR3, PANB_ALCBS ;
DR   Q0AB69, PANB_ALHEH ;  B6ELE1, PANB_ALISL ;  A6TMH9, PANB_ALKMQ ;
DR   B4RYN8, PANB_ALTMD ;  B8J7G7, PANB_ANAD2 ;  Q2IFU2, PANB_ANADE ;
DR   A7HGZ2, PANB_ANADF ;  B9KHN0, PANB_ANAMF ;  Q5PBP6, PANB_ANAMM ;
DR   B4UDZ3, PANB_ANASK ;  B9ML78, PANB_ANATD ;  Q3M672, PANB_ANAVT ;
DR   O67783, PANB_AQUAE ;  A8EVP8, PANB_ARCB4 ;  Q5NXQ3, PANB_AROAE ;
DR   A1R5H8, PANB_ARTAT ;  A0JVB5, PANB_ARTS2 ;  B6YS36, PANB_AZOPC ;
DR   A1KAA5, PANB_AZOSB ;  A7Z5Z4, PANB_BACA2 ;  C3P5Q9, PANB_BACAA ;
DR   C3L8Q0, PANB_BACAC ;  A0RBZ2, PANB_BACAH ;  Q81ST3, PANB_BACAN ;
DR   B7JHQ6, PANB_BACC0 ;  Q73AV4, PANB_BACC1 ;  B7IPB7, PANB_BACC2 ;
DR   C1EN36, PANB_BACC3 ;  B7HHU3, PANB_BACC4 ;  B7HL53, PANB_BACC7 ;
DR   A7GN76, PANB_BACCN ;  Q81FN7, PANB_BACCR ;  Q63DJ3, PANB_BACCZ ;
DR   Q5LD96, PANB_BACFN ;  Q64UB9, PANB_BACFR ;  Q9KC87, PANB_BACHD ;
DR   Q6HL16, PANB_BACHK ;  Q65I56, PANB_BACLD ;  A8FEH7, PANB_BACP2 ;
DR   Q5WGA3, PANB_BACSK ;  P52996, PANB_BACSU ;  Q8A9W7, PANB_BACTN ;
DR   A6L3Y2, PANB_BACV8 ;  A9VME9, PANB_BACWK ;  A1US40, PANB_BARBK ;
DR   Q6G5H3, PANB_BARHE ;  Q6G078, PANB_BARQU ;  A9IRP2, PANB_BART1 ;
DR   Q1LTN1, PANB_BAUCH ;  Q6MHI3, PANB_BDEBA ;  Q7WER7, PANB_BORBR ;
DR   Q7W3E7, PANB_BORPA ;  A9IHJ7, PANB_BORPD ;  Q7VV53, PANB_BORPE ;
DR   B2S9H9, PANB_BRUA1 ;  Q2YPI1, PANB_BRUA2 ;  Q57F29, PANB_BRUAB ;
DR   A9M8B3, PANB_BRUC2 ;  C0RH46, PANB_BRUMB ;  P65654, PANB_BRUME ;
DR   B0CJW1, PANB_BRUSI ;  P65655, PANB_BRUSU ;  B8D8Z6, PANB_BUCA5 ;
DR   P57293, PANB_BUCAI ;  Q8K9U6, PANB_BUCAP ;  B8D7A1, PANB_BUCAT ;
DR   Q1BYX0, PANB_BURCA ;  A9AGB5, PANB_BURM1 ;  A3MN95, PANB_BURM7 ;
DR   A2S561, PANB_BURM9 ;  Q62HD8, PANB_BURMA ;  A1V0V0, PANB_BURMS ;
DR   A3NYX3, PANB_BURP0 ;  Q3JP15, PANB_BURP1 ;  A3ND64, PANB_BURP6 ;
DR   B2JGD9, PANB_BURP8 ;  B2SXC3, PANB_BURPP ;  Q63R49, PANB_BURPS ;
DR   Q2SYZ1, PANB_BURTA ;  A4JBS4, PANB_BURVG ;  Q145E8, PANB_BURXL ;
DR   A8MAX6, PANB_CALMQ ;  A4XMZ4, PANB_CALS8 ;  A7ZEL6, PANB_CAMC1 ;
DR   A7GZP8, PANB_CAMC5 ;  A0RN82, PANB_CAMFF ;  A8FK87, PANB_CAMJ8 ;
DR   A7H574, PANB_CAMJD ;  Q9PIK1, PANB_CAMJE ;  Q29W37, PANB_CAMJJ ;
DR   Q5HWH3, PANB_CAMJR ;  Q3A9L0, PANB_CARHZ ;  B8GVL8, PANB_CAUCN ;
DR   Q9A7R9, PANB_CAUCR ;  A0RXQ5, PANB_CENSY ;  A9WFR7, PANB_CHLAA ;
DR   B8G644, PANB_CHLAD ;  Q3AS53, PANB_CHLCH ;  B3EDF1, PANB_CHLL2 ;
DR   B3QMS8, PANB_CHLP8 ;  B3EQ18, PANB_CHLPB ;  A1BH02, PANB_CHLPD ;
DR   B9LII0, PANB_CHLSY ;  Q8KCS2, PANB_CHLTE ;  Q1QSZ9, PANB_CHRSD ;
DR   Q7NXJ1, PANB_CHRVO ;  A8ALE9, PANB_CITK8 ;  Q97F39, PANB_CLOAB ;
DR   A7FR60, PANB_CLOB1 ;  C3L035, PANB_CLOB6 ;  A6LWN6, PANB_CLOB8 ;
DR   B2V1L8, PANB_CLOBA ;  C1FS97, PANB_CLOBJ ;  B1IEL6, PANB_CLOBK ;
DR   A7GAI6, PANB_CLOBL ;  B1KUY7, PANB_CLOBM ;  Q18C32, PANB_CLOD6 ;
DR   A5N5W0, PANB_CLOK5 ;  A0PXQ3, PANB_CLONN ;  A3DDV7, PANB_CLOTH ;
DR   Q47W60, PANB_COLP3 ;  Q6NEB7, PANB_CORDI ;  Q8FUA5, PANB_COREF ;
DR   A4QAA6, PANB_CORGB ;  Q9X712, PANB_CORGL ;  Q4JWH1, PANB_CORJK ;
DR   B6J9H8, PANB_COXB1 ;  B6J1Q3, PANB_COXB2 ;  A9KEG7, PANB_COXBN ;
DR   Q83EA2, PANB_COXBU ;  Q0K762, PANB_CUPNH ;  Q46XJ2, PANB_CUPPJ ;
DR   B3R6G5, PANB_CUPTR ;  B8HWP9, PANB_CYAP4 ;  B7JVF9, PANB_CYAP8 ;
DR   Q11Q55, PANB_CYTH3 ;  Q47B66, PANB_DECAR ;  Q3Z8B4, PANB_DEHE1 ;
DR   A5FR68, PANB_DEHSB ;  Q3ZXG0, PANB_DEHSC ;  C1CX98, PANB_DEIDV ;
DR   Q1J1C0, PANB_DEIGD ;  Q9RR81, PANB_DEIRA ;  A9BV02, PANB_DELAS ;
DR   B8FFR9, PANB_DESAA ;  C0QFH9, PANB_DESAH ;  Q311U7, PANB_DESDG ;
DR   B8G1S3, PANB_DESHD ;  Q250S5, PANB_DESHY ;  Q6AJ44, PANB_DESPS ;
DR   Q729A6, PANB_DESVH ;  A1VBJ4, PANB_DESVV ;  A7ZHM4, PANB_ECO24 ;
DR   B7UII2, PANB_ECO27 ;  B7MBB7, PANB_ECO45 ;  B7LGJ6, PANB_ECO55 ;
DR   Q8X929, PANB_ECO57 ;  B5YZH1, PANB_ECO5E ;  B7NI94, PANB_ECO7I ;
DR   B7MNZ6, PANB_ECO81 ;  B7M175, PANB_ECO8A ;  C4ZRM7, PANB_ECOBW ;
DR   B1XCA9, PANB_ECODH ;  A7ZW83, PANB_ECOHS ;  A1A7I0, PANB_ECOK1 ;
DR   Q0TLJ8, PANB_ECOL5 ;  Q8FL30, PANB_ECOL6 ;  B1IQK6, PANB_ECOLC ;
DR   P31057, PANB_ECOLI ;  B7N804, PANB_ECOLU ;  B6HZA9, PANB_ECOSE ;
DR   B1LGT6, PANB_ECOSM ;  Q1RG56, PANB_ECOUT ;  C5B9K6, PANB_EDWI9 ;
DR   Q9Y7B6, PANB_EMENI ;  A4W6N8, PANB_ENT38 ;  Q833S5, PANB_ENTFA ;
DR   A7MGP6, PANB_ENTS8 ;  Q6D1X6, PANB_ERWCT ;  B2VD19, PANB_ERWT9 ;
DR   Q2NAY0, PANB_ERYLH ;  B7LW41, PANB_ESCF3 ;  B1YHQ9, PANB_EXIS2 ;
DR   C4L6Q0, PANB_EXISA ;  A5FAQ5, PANB_FLAJ1 ;  Q0RFD5, PANB_FRAAA ;
DR   Q2J886, PANB_FRASC ;  Q14GL1, PANB_FRAT1 ;  A7NB32, PANB_FRATF ;
DR   Q2A4C6, PANB_FRATH ;  B2SFS9, PANB_FRATM ;  A0Q7L2, PANB_FRATN ;
DR   Q0BMQ5, PANB_FRATO ;  Q5NF58, PANB_FRATT ;  A4IWW6, PANB_FRATW ;
DR   B5E846, PANB_GEOBB ;  Q5KXX2, PANB_GEOKA ;  B3E5K9, PANB_GEOLS ;
DR   Q39V51, PANB_GEOMG ;  B9M2A3, PANB_GEOSF ;  Q74CG8, PANB_GEOSL ;
DR   C5D3B3, PANB_GEOSW ;  A4IQ61, PANB_GEOTN ;  A5G3A0, PANB_GEOUR ;
DR   Q7NMK3, PANB_GLOVI ;  A9H9N2, PANB_GLUDA ;  Q0BSQ3, PANB_GRABC ;
DR   A0M360, PANB_GRAFK ;  A1WUU5, PANB_HALHL ;  Q5V3P6, PANB_HALMA ;
DR   B0R5P8, PANB_HALS3 ;  Q9HPT6, PANB_HALSA ;  Q17WP8, PANB_HELAH ;
DR   Q7VIU7, PANB_HELHP ;  B0TC10, PANB_HELMI ;  B6JKW5, PANB_HELP2 ;
DR   B5ZAF6, PANB_HELPG ;  Q1CUB6, PANB_HELPH ;  Q9ZM56, PANB_HELPJ ;
DR   B2USM4, PANB_HELPS ;  O25698, PANB_HELPY ;  A9B2U4, PANB_HERA2 ;
DR   A2BMY4, PANB_HYPBU ;  Q0C444, PANB_HYPNA ;  Q5QVR5, PANB_IDILO ;
DR   A8A9H3, PANB_IGNH4 ;  A6T221, PANB_JANMA ;  B5Y1P5, PANB_KLEP3 ;
DR   A6T4T0, PANB_KLEP7 ;  C5CFR2, PANB_KOSOT ;  Q5X1M8, PANB_LEGPA ;
DR   A5IAR5, PANB_LEGPC ;  Q5ZS58, PANB_LEGPH ;  Q5WTD7, PANB_LEGPL ;
DR   Q6AFH4, PANB_LEIXX ;  B0SAC5, PANB_LEPBA ;  Q04VK1, PANB_LEPBJ ;
DR   Q04XX5, PANB_LEPBL ;  B0STK1, PANB_LEPBP ;  B1Y4K8, PANB_LEPCP ;
DR   Q72MN0, PANB_LEPIC ;  Q8EZ98, PANB_LEPIN ;  Q92AA6, PANB_LISIN ;
DR   C1KWK2, PANB_LISMC ;  Q71YB3, PANB_LISMF ;  B8DC24, PANB_LISMH ;
DR   Q8Y601, PANB_LISMO ;  A0AK07, PANB_LISW6 ;  B1HU19, PANB_LYSSC ;
DR   Q2VZ01, PANB_MAGSA ;  A0L3M6, PANB_MAGSM ;  A1TYE6, PANB_MARAV ;
DR   Q0AQE4, PANB_MARMM ;  A6W2I3, PANB_MARMS ;  Q11F82, PANB_MESSB ;
DR   B7KWY8, PANB_METC4 ;  Q605H0, PANB_METCA ;  A9W3L5, PANB_METEP ;
DR   Q1H3S0, PANB_METFK ;  B1ZHG6, PANB_METPB ;  B1LTL1, PANB_METRJ ;
DR   B0UQT7, PANB_METS4 ;  A4YED8, PANB_METS5 ;  Q2RM79, PANB_MOOTA ;
DR   A0QEV5, PANB_MYCA1 ;  P0C2T4, PANB_MYCBO ;  A1KKR8, PANB_MYCBP ;
DR   Q9CBT0, PANB_MYCLE ;  B2HHM7, PANB_MYCMM ;  Q73YI6, PANB_MYCPA ;
DR   A3Q1U4, PANB_MYCSJ ;  A1UID0, PANB_MYCSK ;  Q1B6P5, PANB_MYCSS ;
DR   P0A5Q8, PANB_MYCTU ;  A0PNG6, PANB_MYCUA ;  Q9L7B2, PANB_MYCVP ;
DR   Q1DAN9, PANB_MYXXD ;  Q3INP4, PANB_NATPD ;  Q5F9F9, PANB_NEIG1 ;
DR   B4RKE5, PANB_NEIG2 ;  Q9JUY0, PANB_NEIMA ;  Q9JZW6, PANB_NEIMB ;
DR   A1KTB1, PANB_NEIMF ;  Q0ADS2, PANB_NITEC ;  Q82Y18, PANB_NITEU ;
DR   Q1QMP7, PANB_NITHX ;  A9A2T9, PANB_NITMS ;  Q2YAN9, PANB_NITMU ;
DR   Q3JCP9, PANB_NITOC ;  A6Q1X8, PANB_NITSB ;  Q3SR08, PANB_NITWN ;
DR   Q5YZ95, PANB_NOCFA ;  A1SIB6, PANB_NOCSJ ;  Q8YWS8, PANB_NOSS1 ;
DR   Q2G6P1, PANB_NOVAD ;  Q8ELF4, PANB_OCEIH ;  B6JGY0, PANB_OLICO ;
DR   A6LA68, PANB_PARD8 ;  A1B2L0, PANB_PARDP ;  A7HYW1, PANB_PARL1 ;
DR   C6DC47, PANB_PECCP ;  Q3A3I6, PANB_PELCD ;  Q3B394, PANB_PELLD ;
DR   B4SAH9, PANB_PELPB ;  A1AUV8, PANB_PELPD ;  Q4FMW6, PANB_PELUB ;
DR   B4RAD7, PANB_PHEZH ;  Q7N869, PANB_PHOLL ;  Q6LMJ6, PANB_PHOPR ;
DR   A1VKS3, PANB_POLNA ;  Q12F40, PANB_POLSJ ;  B2RIF8, PANB_PORG3 ;
DR   Q7MWM0, PANB_PORGI ;  B4S8V9, PANB_PROA2 ;  A3PEE4, PANB_PROM0 ;
DR   A2C476, PANB_PROM1 ;  A8G6C1, PANB_PROM2 ;  A2CB80, PANB_PROM3 ;
DR   A2BY17, PANB_PROM5 ;  Q319H9, PANB_PROM9 ;  Q93JX5, PANB_PROMA ;
DR   B4EUD3, PANB_PROMH ;  Q7TV48, PANB_PROMM ;  Q7TU60, PANB_PROMP ;
DR   A2BSN1, PANB_PROMS ;  Q46JG1, PANB_PROMT ;  A4SE31, PANB_PROVI ;
DR   Q48N86, PANB_PSE14 ;  Q15NV5, PANB_PSEA6 ;  Q9ZEP8, PANB_PSEFS ;
DR   Q3ILK1, PANB_PSEHT ;  A4XYC4, PANB_PSEMY ;  A5W974, PANB_PSEP1 ;
DR   Q3K6Q6, PANB_PSEPF ;  Q88DW9, PANB_PSEPK ;  B1J2C2, PANB_PSEPW ;
DR   Q888Q5, PANB_PSESM ;  Q4ZY86, PANB_PSEU2 ;  A4VPM6, PANB_PSEU5 ;
DR   Q4FVG8, PANB_PSYA2 ;  Q1QEJ4, PANB_PSYCK ;  A1SSG9, PANB_PSYIN ;
DR   A5WHD0, PANB_PSYWF ;  Q9V0E1, PANB_PYRAB ;  Q8ZT69, PANB_PYRAE ;
DR   A4WMD4, PANB_PYRAR ;  A3MWA6, PANB_PYRCJ ;  Q8U1R2, PANB_PYRFU ;
DR   O58665, PANB_PYRHO ;  A1RU92, PANB_PYRIL ;  Q5JCY6, PANB_PYRKO ;
DR   Q1LJ86, PANB_RALME ;  B2UBN8, PANB_RALPJ ;  Q8XW45, PANB_RALSO ;
DR   Q2JZU0, PANB_RHIEC ;  Q1M4A0, PANB_RHIL3 ;  Q98NC9, PANB_RHILO ;
DR   Q92NN1, PANB_RHIME ;  C3MEL6, PANB_RHISN ;  Q7UM39, PANB_RHOBA ;
DR   B6IX34, PANB_RHOCS ;  Q21U09, PANB_RHOFD ;  Q2IXB0, PANB_RHOP2 ;
DR   Q07LA4, PANB_RHOP5 ;  Q6N583, PANB_RHOPA ;  Q215V6, PANB_RHOPB ;
DR   Q135K5, PANB_RHOPS ;  B3Q9V6, PANB_RHOPT ;  Q2RP30, PANB_RHORT ;
DR   A3PGQ2, PANB_RHOS1 ;  Q3J5N1, PANB_RHOS4 ;  A4WVH0, PANB_RHOS5 ;
DR   Q0SHJ0, PANB_RHOSR ;  A7NG79, PANB_ROSCS ;  Q16DW5, PANB_ROSDO ;
DR   A5URA8, PANB_ROSS1 ;  A1AW70, PANB_RUTMC ;  Q21F95, PANB_SACD2 ;
DR   A4FA49, PANB_SACEN ;  B5F833, PANB_SALA4 ;  A9MPM1, PANB_SALAR ;
DR   Q57T73, PANB_SALCH ;  B5FIX8, PANB_SALDC ;  B5R3E6, PANB_SALEP ;
DR   B5RHC1, PANB_SALG2 ;  B4TK05, PANB_SALHS ;  B4SUA8, PANB_SALNS ;
DR   Q5PIN3, PANB_SALPA ;  C0Q5P4, PANB_SALPC ;  B5BL65, PANB_SALPK ;
DR   Q2S1H6, PANB_SALRD ;  Q8Z9D2, PANB_SALTI ;  Q8ZRR0, PANB_SALTY ;
DR   Q09672, PANB_SCHPO ;  A1S3M7, PANB_SHEAM ;  Q12JC6, PANB_SHEDO ;
DR   Q07XZ8, PANB_SHEFN ;  B0TTI2, PANB_SHEHH ;  A3QHQ1, PANB_SHELP ;
DR   Q8EIG9, PANB_SHEON ;  A8H0D4, PANB_SHEPA ;  A4YA61, PANB_SHEPC ;
DR   B8CTC6, PANB_SHEPW ;  A0L0R2, PANB_SHESA ;  A8G084, PANB_SHESH ;
DR   Q0HMB1, PANB_SHESM ;  Q0HRH6, PANB_SHESR ;  A1RG67, PANB_SHESW ;
DR   B1KEP6, PANB_SHEWM ;  B2U2Y1, PANB_SHIB3 ;  Q326A3, PANB_SHIBS ;
DR   Q32JW9, PANB_SHIDS ;  Q0T867, PANB_SHIF8 ;  Q83ME5, PANB_SHIFL ;
DR   Q3Z5M6, PANB_SHISS ;  Q5LWP5, PANB_SILPO ;  Q1GLQ6, PANB_SILST ;
DR   A6UB62, PANB_SINMW ;  Q2NVR2, PANB_SODGM ;  Q1GR07, PANB_SPHAL ;
DR   A7X6X7, PANB_STAA1 ;  A6U4X9, PANB_STAA2 ;  Q2FDR0, PANB_STAA3 ;
DR   Q2FV21, PANB_STAA8 ;  A5IW24, PANB_STAA9 ;  Q2YWF9, PANB_STAAB ;
DR   Q5HCV3, PANB_STAAC ;  A6QK86, PANB_STAAE ;  Q931E6, PANB_STAAM ;
DR   P65656, PANB_STAAN ;  Q6GDK4, PANB_STAAR ;  Q6G677, PANB_STAAS ;
DR   A8Z3J9, PANB_STAAT ;  P65657, PANB_STAAW ;  B9DKF4, PANB_STACT ;
DR   Q5HL35, PANB_STAEQ ;  Q8CR20, PANB_STAES ;  Q4LA35, PANB_STAHJ ;
DR   A3DPB2, PANB_STAMF ;  Q4A0U0, PANB_STAS1 ;  Q82AW2, PANB_STRAW ;
DR   Q9RKS2, PANB_STRCO ;  B4SRY3, PANB_STRM5 ;  B2FL67, PANB_STRMK ;
DR   Q4JA70, PANB_SULAC ;  Q30PX5, PANB_SULDN ;  C3N136, PANB_SULIA ;
DR   C4KKA3, PANB_SULIK ;  C3MK79, PANB_SULIL ;  C3MU48, PANB_SULIM ;
DR   C3NMB9, PANB_SULIN ;  C3N926, PANB_SULIY ;  Q97W44, PANB_SULSO ;
DR   Q974Y0, PANB_SULTO ;  Q2LTJ5, PANB_SYNAS ;  Q31KK8, PANB_SYNE7 ;
DR   A0LLW3, PANB_SYNFM ;  Q2JRY1, PANB_SYNJA ;  Q2JNI1, PANB_SYNJB ;
DR   B1XQ35, PANB_SYNP2 ;  Q5N1A6, PANB_SYNP6 ;  Q7TTU0, PANB_SYNPX ;
DR   A5GRJ3, PANB_SYNR3 ;  Q0IC75, PANB_SYNS3 ;  Q3AVB7, PANB_SYNS9 ;
DR   Q3ALB9, PANB_SYNSC ;  Q0B0P6, PANB_SYNWW ;  P52997, PANB_SYNY3 ;
DR   B7IDK8, PANB_THEAB ;  Q8DM44, PANB_THEEB ;  Q47R98, PANB_THEFY ;
DR   A8F498, PANB_THELT ;  A6LMK5, PANB_THEM4 ;  Q9X251, PANB_THEMA ;
DR   B9K819, PANB_THENN ;  B1YBD4, PANB_THENV ;  B0KC90, PANB_THEP3 ;
DR   B0K365, PANB_THEPX ;  B1LAU5, PANB_THESQ ;  Q72LM0, PANB_THET2 ;
DR   Q5SL86, PANB_THET8 ;  Q31FF5, PANB_THICR ;  Q3SH83, PANB_THIDA ;
DR   C4L929, PANB_TOLAT ;  Q10WG3, PANB_TRIEI ;  Q83HM1, PANB_TROW8 ;
DR   Q83GK7, PANB_TROWT ;  B1GZJ8, PANB_UNCTG ;  A1WDW4, PANB_VEREI ;
DR   A5CX20, PANB_VESOH ;  A5F975, PANB_VIBC3 ;  Q9KUD0, PANB_VIBCH ;
DR   C3LS82, PANB_VIBCM ;  B5FB05, PANB_VIBFM ;  A7MYX2, PANB_VIBHB ;
DR   Q87LV2, PANB_VIBPA ;  B7VK03, PANB_VIBSL ;  Q8DC11, PANB_VIBVU ;
DR   Q7MHV4, PANB_VIBVY ;  Q8D2A5, PANB_WIGBR ;  Q7M878, PANB_WOLSU ;
DR   Q8PLL1, PANB_XANAC ;  Q3BUL6, PANB_XANC5 ;  Q4UTV5, PANB_XANC8 ;
DR   B0RTU1, PANB_XANCB ;  Q8P9T0, PANB_XANCP ;  Q2P377, PANB_XANOM ;
DR   B2SJL8, PANB_XANOP ;  Q5H0A3, PANB_XANOR ;  A7IF97, PANB_XANP2 ;
DR   B2I720, PANB_XYLF2 ;  Q9PGR9, PANB_XYLFA ;  B0U1Q2, PANB_XYLFM ;
DR   Q87EW0, PANB_XYLFT ;  P38122, PANB_YEAST ;  A1JJN8, PANB_YERE8 ;
DR   A7FM22, PANB_YERP3 ;  Q1C3V8, PANB_YERPA ;  B2K534, PANB_YERPB ;
DR   Q8ZBK8, PANB_YERPE ;  A9R1G2, PANB_YERPG ;  Q1CLW0, PANB_YERPN ;
DR   A4TPV5, PANB_YERPP ;  Q66EG3, PANB_YERPS ;  B1JK35, PANB_YERPY ;
//
ID   2.1.2.12
DE   Transferred entry: 2.1.1.74.
//
ID   2.1.2.13
DE   UDP-4-amino-4-deoxy-L-arabinose formyltransferase.
AN   ArnAFT.
AN   UDP-L-Ara4N formyltransferase.
CA   10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinose =
CA   5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4-formamido-beta-L-arabinose.
CC   -!- The activity is part of a bifunctional enzyme also performing the
CC       reaction of EC 1.1.1.305.
CC   -!- Formerly EC 2.1.2.n1.
DR   A0KGY6, ARNA_AERHH ;  A4SQW9, ARNA_AERS4 ;  A7ZP73, ARNA_ECO24 ;
DR   B7UFR7, ARNA_ECO27 ;  B7MG22, ARNA_ECO45 ;  B7LAS0, ARNA_ECO55 ;
DR   Q8XDZ3, ARNA_ECO57 ;  B5YXP8, ARNA_ECO5E ;  B7NNT4, ARNA_ECO7I ;
DR   B7MXT6, ARNA_ECO81 ;  B7M5T7, ARNA_ECO8A ;  C4ZU97, ARNA_ECOBW ;
DR   B1X8W8, ARNA_ECODH ;  A8A2C2, ARNA_ECOHS ;  A1ADA7, ARNA_ECOK1 ;
DR   Q0TFI7, ARNA_ECOL5 ;  Q8FFM1, ARNA_ECOL6 ;  B1IXT2, ARNA_ECOLC ;
DR   P77398, ARNA_ECOLI ;  B7N5M0, ARNA_ECOLU ;  B6I7J8, ARNA_ECOSE ;
DR   B1LLK9, ARNA_ECOSM ;  Q1R9G0, ARNA_ECOUT ;  A4WAM3, ARNA_ENT38 ;
DR   Q6D2F1, ARNA_ERWCT ;  B2VBI9, ARNA_ERWT9 ;  B7LM76, ARNA_ESCF3 ;
DR   B5XTK9, ARNA_KLEP3 ;  A6TF98, ARNA_KLEP7 ;  C6DAW5, ARNA_PECCP ;
DR   Q7N3Q7, ARNA_PHOLL ;  B4ETL7, ARNA_PROMH ;  Q48HZ1, ARNA_PSE14 ;
DR   A6V1P0, ARNA_PSEA7 ;  B7VBN2, ARNA_PSEA8 ;  Q02R25, ARNA_PSEAB ;
DR   Q9HY63, ARNA_PSEAE ;  Q4KC82, ARNA_PSEF5 ;  C3KAD2, ARNA_PSEFS ;
DR   Q3KCC1, ARNA_PSEPF ;  Q4ZSZ2, ARNA_PSEU2 ;  B5EZH8, ARNA_SALA4 ;
DR   P0C0R6, ARNA_SALCH ;  B5FNT9, ARNA_SALDC ;  B5R272, ARNA_SALEP ;
DR   B5RCC4, ARNA_SALG2 ;  B4TBG6, ARNA_SALHS ;  B4SYX1, ARNA_SALNS ;
DR   Q5PNA6, ARNA_SALPA ;  A9N5B2, ARNA_SALPB ;  C0Q069, ARNA_SALPC ;
DR   B5BCP6, ARNA_SALPK ;  B4TPI2, ARNA_SALSV ;  Q8Z540, ARNA_SALTI ;
DR   O52325, ARNA_SALTY ;  A8GDR7, ARNA_SERP5 ;  A8FRR2, ARNA_SHESH ;
DR   B2TW38, ARNA_SHIB3 ;  Q31YK2, ARNA_SHIBS ;  Q32DT3, ARNA_SHIDS ;
DR   Q0T2M8, ARNA_SHIF8 ;  Q83QT8, ARNA_SHIFL ;  Q3YZV1, ARNA_SHISS ;
DR   Q2NRV7, ARNA_SODGM ;  Q8D341, ARNA_WIGBR ;  A1JPN5, ARNA_YERE8 ;
DR   A7FHH4, ARNA_YERP3 ;  Q1C742, ARNA_YERPA ;  B2K5L3, ARNA_YERPB ;
DR   Q8ZDX8, ARNA_YERPE ;  A9R093, ARNA_YERPG ;  Q1CIH7, ARNA_YERPN ;
DR   A4TIM4, ARNA_YERPP ;  Q93PD8, ARNA_YERPS ;  B1JJ30, ARNA_YERPY ;
//
ID   2.1.2.n1
DE   Transferred entry: 2.1.2.13.
//
ID   2.1.3.1
DE   Methylmalonyl-CoA carboxytransferase.
AN   Methylmalonyl-CoA carboxyltransferase.
AN   Transcarboxylase.
CA   (S)-methylmalonyl-CoA + pyruvate = propanoyl-CoA + oxaloacetate.
CF   Biotin; Cobalt; Zinc.
PR   PROSITE; PDOC00167;
DR   Q8GBW6, 12S_PROFR  ;  Q70AC7, 5S_PROFR   ;  P02904, BCCP_PROFR ;
//
ID   2.1.3.2
DE   Aspartate carbamoyltransferase.
AN   Aspartate transcarbamylase.
AN   ATCase.
AN   Carbamylaspartotranskinase.
CA   Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate.
PR   PROSITE; PDOC00091;
DR   P20054, PYR1_DICDI ;  P05990, PYR1_DROME ;  O93937, PYR1_EMENI ;
DR   P27708, PYR1_HUMAN ;  P08955, PYR1_MESAU ;  Q09794, PYR1_SCHPO ;
DR   Q91437, PYR1_SQUAC ;  P07259, PYR1_YEAST ;  Q43086, PYRB1_PEA  ;
DR   B0TSQ4, PYRB1_SHEHH;  Q43087, PYRB2_PEA  ;  B0TST3, PYRB2_SHEHH;
DR   Q43064, PYRB3_PEA  ;  B0TPF3, PYRB3_SHEHH;  B0CED7, PYRB_ACAM1 ;
DR   A1TKM0, PYRB_ACIAC ;  Q6FCR5, PYRB_ACIAD ;  B7GWH6, PYRB_ACIB3 ;
DR   B7IAG6, PYRB_ACIB5 ;  B2HWY0, PYRB_ACIBC ;  Q1IHT1, PYRB_ACIBL ;
DR   B0VLH2, PYRB_ACIBS ;  A3M3X6, PYRB_ACIBT ;  B0VAL3, PYRB_ACIBY ;
DR   A0LUG3, PYRB_ACIC1 ;  A5FWH1, PYRB_ACICJ ;  B9MF57, PYRB_ACIET ;
DR   B7JAG8, PYRB_ACIF2 ;  B5EQG3, PYRB_ACIF5 ;  A1WBQ7, PYRB_ACISJ ;
DR   A0KQG0, PYRB_AERHH ;  Q9YBD4, PYRB_AERPE ;  A4SHP8, PYRB_AERS4 ;
DR   B9JDM0, PYRB_AGRRK ;  Q8UFT9, PYRB_AGRT5 ;  B9JVI4, PYRB_AGRVS ;
DR   B2ULR3, PYRB_AKKM8 ;  Q0VTM5, PYRB_ALCBS ;  Q0ABT6, PYRB_ALHEH ;
DR   B6EMS5, PYRB_ALISL ;  A6TVR2, PYRB_ALKMQ ;  A8MIU1, PYRB_ALKOO ;
DR   B8JAE9, PYRB_ANAD2 ;  Q2IIB1, PYRB_ANADE ;  A7HCE9, PYRB_ANADF ;
DR   Q5PAN5, PYRB_ANAMM ;  Q2GKK3, PYRB_ANAPZ ;  B4UDQ3, PYRB_ANASK ;
DR   B9MS21, PYRB_ANATD ;  Q3MDY8, PYRB_ANAVT ;  O66726, PYRB_AQUAE ;
DR   P49077, PYRB_ARATH ;  A8ERG2, PYRB_ARCB4 ;  O30130, PYRB_ARCFU ;
DR   Q5P6I4, PYRB_AROAE ;  A1R6Z7, PYRB_ARTAT ;  B8H8U9, PYRB_ARTCA ;
DR   A0JX76, PYRB_ARTS2 ;  A8ICW0, PYRB_AZOC5 ;  B6YRC6, PYRB_AZOPC ;
DR   A1KB72, PYRB_AZOSB ;  C1DI75, PYRB_AZOVD ;  A7Z4G9, PYRB_BACA2 ;
DR   C3P659, PYRB_BACAA ;  C3L737, PYRB_BACAC ;  A0RHR1, PYRB_BACAH ;
DR   Q81WE9, PYRB_BACAN ;  B7JJX6, PYRB_BACC0 ;  Q732I0, PYRB_BACC1 ;
DR   B7IUP9, PYRB_BACC2 ;  C1EPQ3, PYRB_BACC3 ;  B7H6M5, PYRB_BACC4 ;
DR   B7HLM3, PYRB_BACC7 ;  P41008, PYRB_BACCL ;  A7GRL4, PYRB_BACCN ;
DR   B9IVW6, PYRB_BACCQ ;  Q819S0, PYRB_BACCR ;  Q636D7, PYRB_BACCZ ;
DR   Q5LD54, PYRB_BACFN ;  Q64U74, PYRB_BACFR ;  Q9K9V6, PYRB_BACHD ;
DR   Q6HES5, PYRB_BACHK ;  Q65JV0, PYRB_BACLD ;  A8FD14, PYRB_BACP2 ;
DR   Q5WFI9, PYRB_BACSK ;  P05654, PYRB_BACSU ;  Q8A9S3, PYRB_BACTN ;
DR   A6L5J9, PYRB_BACV8 ;  A9VTC9, PYRB_BACWK ;  A1UT24, PYRB_BARBK ;
DR   Q6G3F3, PYRB_BARHE ;  Q6FZS5, PYRB_BARQU ;  A9IU46, PYRB_BART1 ;
DR   Q1LTK6, PYRB_BAUCH ;  B2IEN5, PYRB_BEII9 ;  C5C683, PYRB_BEUC1 ;
DR   A1A1F7, PYRB_BIFAA ;  B3DS61, PYRB_BIFLD ;  Q8G655, PYRB_BIFLO ;
DR   B7GRV4, PYRB_BIFLS ;  Q7WF77, PYRB_BORBR ;  Q7W3U7, PYRB_BORPA ;
DR   Q7W044, PYRB_BORPE ;  C0QVX1, PYRB_BRAHW ;  Q89K19, PYRB_BRAJA ;
DR   A5EKQ8, PYRB_BRASB ;  A4YWG4, PYRB_BRASO ;  B2SB57, PYRB_BRUA1 ;
DR   Q2YKL8, PYRB_BRUA2 ;  Q577Z8, PYRB_BRUAB ;  A9MBN9, PYRB_BRUC2 ;
DR   C0RLC0, PYRB_BRUMB ;  P65611, PYRB_BRUME ;  A5VUT1, PYRB_BRUO2 ;
DR   A9WYR8, PYRB_BRUSI ;  P65612, PYRB_BRUSU ;  B8D9F4, PYRB_BUCA5 ;
DR   P57450, PYRB_BUCAI ;  Q8K9H9, PYRB_BUCAP ;  B8D7Q6, PYRB_BUCAT ;
DR   B1YU30, PYRB_BURA4 ;  Q1BYK8, PYRB_BURCA ;  B1JWP2, PYRB_BURCC ;
DR   A0K543, PYRB_BURCH ;  B4ECT0, PYRB_BURCJ ;  Q0BHS4, PYRB_BURCM ;
DR   A9AFI4, PYRB_BURM1 ;  A3MMA7, PYRB_BURM7 ;  A2S9T2, PYRB_BURM9 ;
DR   Q62I89, PYRB_BURMA ;  A1V206, PYRB_BURMS ;  A3NYG2, PYRB_BURP0 ;
DR   Q3JPG4, PYRB_BURP1 ;  A3NCQ0, PYRB_BURP6 ;  B2T0I7, PYRB_BURPP ;
DR   Q63RI2, PYRB_BURPS ;  Q39J02, PYRB_BURS3 ;  Q2SYI8, PYRB_BURTA ;
DR   A4JC10, PYRB_BURVG ;  Q144P9, PYRB_BURXL ;  A8MAC7, PYRB_CALMQ ;
DR   A4XKT1, PYRB_CALS8 ;  A7ZEC2, PYRB_CAMC1 ;  A7GXT8, PYRB_CAMC5 ;
DR   A0RQX6, PYRB_CAMFF ;  A7I1Y4, PYRB_CAMHC ;  A8FMF1, PYRB_CAMJ8 ;
DR   A7H2Q9, PYRB_CAMJD ;  Q9PNJ6, PYRB_CAMJE ;  A1W085, PYRB_CAMJJ ;
DR   Q5HU06, PYRB_CAMJR ;  B9KCT6, PYRB_CAMLR ;  Q3AC00, PYRB_CARHZ ;
DR   Q9A5K4, PYRB_CAUCR ;  B0T190, PYRB_CAUSK ;  B3PKF2, PYRB_CELJU ;
DR   A0RXJ5, PYRB_CENSY ;  A9WDU7, PYRB_CHLAA ;  B8G8T0, PYRB_CHLAD ;
DR   Q3AQY1, PYRB_CHLCH ;  B3EEL7, PYRB_CHLL2 ;  B3QQ34, PYRB_CHLP8 ;
DR   A1BEE6, PYRB_CHLPD ;  B9LFU5, PYRB_CHLSY ;  Q8KBI7, PYRB_CHLTE ;
DR   Q7P145, PYRB_CHRVO ;  A8AMC8, PYRB_CITK8 ;  A5CRX9, PYRB_CLAM3 ;
DR   B0REW3, PYRB_CLAMS ;  Q97FS3, PYRB_CLOAB ;  A7FYJ2, PYRB_CLOB1 ;
DR   C3KU87, PYRB_CLOB6 ;  A6LS54, PYRB_CLOB8 ;  B2UW93, PYRB_CLOBA ;
DR   B2TNG3, PYRB_CLOBB ;  A5I6X1, PYRB_CLOBH ;  C1FLB6, PYRB_CLOBJ ;
DR   B1INE7, PYRB_CLOBK ;  A7GII2, PYRB_CLOBL ;  B1L1E7, PYRB_CLOBM ;
DR   B8I769, PYRB_CLOCE ;  Q18CS8, PYRB_CLOD6 ;  B9E695, PYRB_CLOK1 ;
DR   A5N2L8, PYRB_CLOK5 ;  A0Q2N5, PYRB_CLONN ;  Q0TRA8, PYRB_CLOP1 ;
DR   Q8XL59, PYRB_CLOPE ;  A9KNJ3, PYRB_CLOPH ;  Q0STN4, PYRB_CLOPS ;
DR   A3DE08, PYRB_CLOTH ;  B5YA17, PYRB_COPPD ;  C3PG15, PYRB_CORA7 ;
DR   Q6NH13, PYRB_CORDI ;  Q8FT39, PYRB_COREF ;  A4QEI7, PYRB_CORGB ;
DR   Q8NQ38, PYRB_CORGL ;  Q4JVG8, PYRB_CORJK ;  C4LIU1, PYRB_CORK4 ;
DR   B1VDM8, PYRB_CORU7 ;  B6J6M5, PYRB_COXB1 ;  B6J3V8, PYRB_COXB2 ;
DR   A9KDE9, PYRB_COXBN ;  A9NBU3, PYRB_COXBR ;  Q83A16, PYRB_COXBU ;
DR   Q0K7N2, PYRB_CUPNH ;  Q474U3, PYRB_CUPPJ ;  B3R5Y0, PYRB_CUPTR ;
DR   Q11YY8, PYRB_CYTH3 ;  Q478W3, PYRB_DECAR ;  Q3Z787, PYRB_DEHE1 ;
DR   A5FQE1, PYRB_DEHSB ;  Q3ZY97, PYRB_DEHSC ;  Q1J129, PYRB_DEIGD ;
DR   Q9RVC0, PYRB_DEIRA ;  A9BY86, PYRB_DELAS ;  C0QJ55, PYRB_DESAH ;
DR   B1I4N1, PYRB_DESAP ;  B8J2A8, PYRB_DESDA ;  Q30X38, PYRB_DESDG ;
DR   B8FT13, PYRB_DESHD ;  Q24TJ1, PYRB_DESHY ;  A8ZU12, PYRB_DESOH ;
DR   Q6AS40, PYRB_DESPS ;  A4J555, PYRB_DESRM ;  Q727F4, PYRB_DESVH ;
DR   B8DRT6, PYRB_DESVM ;  A1VAM1, PYRB_DESVV ;  A5EVP6, PYRB_DICNV ;
DR   A8LL75, PYRB_DINSH ;  A7ZVC7, PYRB_ECO24 ;  B7UQQ5, PYRB_ECO27 ;
DR   B7MLQ3, PYRB_ECO45 ;  B7LCV3, PYRB_ECO55 ;  P0A788, PYRB_ECO57 ;
DR   B5Z3K3, PYRB_ECO5E ;  B7NUG1, PYRB_ECO7I ;  B7MTC3, PYRB_ECO81 ;
DR   B7M9K5, PYRB_ECO8A ;  C4ZRB8, PYRB_ECOBW ;  B1XEM6, PYRB_ECODH ;
DR   A8A803, PYRB_ECOHS ;  A1AJF0, PYRB_ECOK1 ;  Q0T9E3, PYRB_ECOL5 ;
DR   P0A787, PYRB_ECOL6 ;  B1ISW0, PYRB_ECOLC ;  P0A786, PYRB_ECOLI ;
DR   B7NGH8, PYRB_ECOLU ;  B6I2F9, PYRB_ECOSE ;  B1LRD2, PYRB_ECOSM ;
DR   Q1R309, PYRB_ECOUT ;  Q3YS44, PYRB_EHRCJ ;  Q2GGK2, PYRB_EHRCR ;
DR   Q5FGW9, PYRB_EHRRG ;  Q5HBA3, PYRB_EHRRW ;  A4W605, PYRB_ENT38 ;
DR   Q9L4T8, PYRB_ENTFA ;  A7MQG0, PYRB_ENTS8 ;  Q6DA73, PYRB_ERWCT ;
DR   Q2NDE3, PYRB_ERYLH ;  B7LMR8, PYRB_ESCF3 ;  B0S198, PYRB_FINM2 ;
DR   A5FB79, PYRB_FLAJ1 ;  A6H0I8, PYRB_FLAPJ ;  Q0RF77, PYRB_FRAAA ;
DR   Q2J833, PYRB_FRASC ;  A8LE09, PYRB_FRASN ;  Q8RG89, PYRB_FUSNN ;
DR   C1A8J7, PYRB_GEMAT ;  B5EB49, PYRB_GEOBB ;  Q5L0U6, PYRB_GEOKA ;
DR   B3E3I2, PYRB_GEOLS ;  Q39US4, PYRB_GEOMG ;  B9M4S3, PYRB_GEOSF ;
DR   Q74DP5, PYRB_GEOSL ;  C6DZ52, PYRB_GEOSM ;  C5D8P7, PYRB_GEOSW ;
DR   A4IM30, PYRB_GEOTN ;  A5GF41, PYRB_GEOUR ;  Q7NCV1, PYRB_GLOVI ;
DR   A9GZR7, PYRB_GLUDA ;  Q5FRG8, PYRB_GLUOX ;  Q0BTZ5, PYRB_GRABC ;
DR   A0M2G8, PYRB_GRAFK ;  Q2SPG7, PYRB_HAHCH ;  A1WVK5, PYRB_HALHL ;
DR   B9LND9, PYRB_HALLT ;  Q5V2T3, PYRB_HALMA ;  B8CWM4, PYRB_HALOH ;
DR   Q9HHN4, PYRB_HALSA ;  Q18J05, PYRB_HALWD ;  C4K7I6, PYRB_HAMD5 ;
DR   Q17XN9, PYRB_HELAH ;  Q7VIT3, PYRB_HELHP ;  B0TGQ3, PYRB_HELMI ;
DR   B6JKT9, PYRB_HELP2 ;  B5ZAD2, PYRB_HELPG ;  Q1CUE2, PYRB_HELPH ;
DR   Q9ZM81, PYRB_HELPJ ;  B2USJ6, PYRB_HELPS ;  O25716, PYRB_HELPY ;
DR   A4G8L8, PYRB_HERAR ;  A2BJ24, PYRB_HYPBU ;  Q0BZU6, PYRB_HYPNA ;
DR   A8A8H6, PYRB_IGNH4 ;  A6T290, PYRB_JANMA ;  Q28KE3, PYRB_JANSC ;
DR   A6WCD0, PYRB_KINRD ;  B5Y2U6, PYRB_KLEP3 ;  A6THH4, PYRB_KLEP7 ;
DR   B1L385, PYRB_KORCO ;  Q5FJB7, PYRB_LACAC ;  Q038Y9, PYRB_LACC3 ;
DR   Q1G866, PYRB_LACDA ;  Q047M5, PYRB_LACDB ;  Q043A9, PYRB_LACGA ;
DR   A8YVZ6, PYRB_LACH4 ;  Q74J31, PYRB_LACJO ;  Q9CF79, PYRB_LACLA ;
DR   Q60252, PYRB_LACLE ;  Q9L4N6, PYRB_LACLM ;  Q02XW6, PYRB_LACLS ;
DR   P77883, PYRB_LACPL ;  A5VHS1, PYRB_LACRD ;  B2G5A1, PYRB_LACRJ ;
DR   Q1WVB2, PYRB_LACS1 ;  Q38X27, PYRB_LACSS ;  C1D9A7, PYRB_LARHH ;
DR   Q1MQ55, PYRB_LAWIP ;  Q5X7G7, PYRB_LEGPA ;  A5IGX6, PYRB_LEGPC ;
DR   Q5ZXZ2, PYRB_LEGPH ;  Q5WYW3, PYRB_LEGPL ;  Q6AF88, PYRB_LEIXX ;
DR   B0SEH6, PYRB_LEPBA ;  Q04UL7, PYRB_LEPBJ ;  Q04YW0, PYRB_LEPBL ;
DR   B0SMK5, PYRB_LEPBP ;  B1Y8E7, PYRB_LEPCP ;  Q72NJ5, PYRB_LEPIC ;
DR   Q8F812, PYRB_LEPIN ;  B1MZ77, PYRB_LEUCK ;  Q03WW4, PYRB_LEUMM ;
DR   Q92AH0, PYRB_LISIN ;  C1KWD7, PYRB_LISMC ;  Q71YH8, PYRB_LISMF ;
DR   B8DDR4, PYRB_LISMH ;  Q8Y662, PYRB_LISMO ;  A0AJU3, PYRB_LISW6 ;
DR   B9EB66, PYRB_MACCJ ;  Q2W156, PYRB_MAGSA ;  A0L3T9, PYRB_MAGSM ;
DR   A1U761, PYRB_MARAV ;  Q0ANY2, PYRB_MARMM ;  A6VSP9, PYRB_MARMS ;
DR   Q11IM0, PYRB_MESSB ;  A6UWP3, PYRB_META3 ;  Q8THL2, PYRB_METAC ;
DR   Q46DA6, PYRB_METBF ;  Q12ZP0, PYRB_METBU ;  B7KW98, PYRB_METC4 ;
DR   Q605F1, PYRB_METCA ;  A9W737, PYRB_METEP ;  Q1GZG8, PYRB_METFK ;
DR   Q2FN12, PYRB_METHJ ;  Q58976, PYRB_METJA ;  Q8TVB2, PYRB_METKA ;
DR   A2SRK7, PYRB_METLZ ;  A4G0R3, PYRB_METM5 ;  A9A906, PYRB_METM6 ;
DR   A6VHS2, PYRB_METM7 ;  Q8PXK5, PYRB_METMA ;  A3CW66, PYRB_METMJ ;
DR   Q6LWQ0, PYRB_METMP ;  B1ZLL0, PYRB_METPB ;  B8GF03, PYRB_METPE ;
DR   A2SDN1, PYRB_METPP ;  A5UMP0, PYRB_METS3 ;  A4YI52, PYRB_METS5 ;
DR   Q2NIC0, PYRB_METST ;  O27464, PYRB_METTH ;  A0B8L1, PYRB_METTP ;
DR   A6UQU0, PYRB_METVS ;  B0JR45, PYRB_MICAN ;  C5CCF5, PYRB_MICLC ;
DR   Q2RK43, PYRB_MOOTA ;  A0QI37, PYRB_MYCA1 ;  B1MCD9, PYRB_MYCA9 ;
DR   P65614, PYRB_MYCBO ;  A1KIG9, PYRB_MYCBP ;  C1AN25, PYRB_MYCBT ;
DR   A4TBY0, PYRB_MYCGI ;  B8ZUL1, PYRB_MYCLB ;  Q9CCR5, PYRB_MYCLE ;
DR   B2HNE6, PYRB_MYCMM ;  Q741H5, PYRB_MYCPA ;  Q8EUX9, PYRB_MYCPE ;
DR   A0QWS1, PYRB_MYCS2 ;  A3PZ61, PYRB_MYCSJ ;  A1UFK0, PYRB_MYCSK ;
DR   Q1B9G3, PYRB_MYCSS ;  A5U282, PYRB_MYCTA ;  P65613, PYRB_MYCTU ;
DR   A0PPI8, PYRB_MYCUA ;  A1T8G7, PYRB_MYCVP ;  Q1D6L9, PYRB_MYXXD ;
DR   Q3IPU8, PYRB_NATPD ;  B2A2U7, PYRB_NATTJ ;  Q5F5P0, PYRB_NEIG1 ;
DR   B4RPW7, PYRB_NEIG2 ;  A9M469, PYRB_NEIM0 ;  P65615, PYRB_NEIMA ;
DR   P65616, PYRB_NEIMB ;  A1KRE1, PYRB_NEIMF ;  Q0AIU3, PYRB_NITEC ;
DR   Q82U44, PYRB_NITEU ;  Q1QL23, PYRB_NITHX ;  A9A2Q5, PYRB_NITMS ;
DR   Q2Y651, PYRB_NITMU ;  Q3JE55, PYRB_NITOC ;  A6Q1Y1, PYRB_NITSB ;
DR   Q3SR25, PYRB_NITWN ;  Q5YTM0, PYRB_NOCFA ;  A1SJE8, PYRB_NOCSJ ;
DR   Q8YWD2, PYRB_NOSS1 ;  Q2G3S7, PYRB_NOVAD ;  Q8ER38, PYRB_OCEIH ;
DR   A6X568, PYRB_OCHA4 ;  Q04H32, PYRB_OENOB ;  B6JFV4, PYRB_OLICO ;
DR   B1ZT05, PYRB_OPITP ;  A6LA97, PYRB_PARD8 ;  A1B548, PYRB_PARDP ;
DR   A7HX10, PYRB_PARL1 ;  C6DJL3, PYRB_PECCP ;  Q03HB3, PYRB_PEDPA ;
DR   Q3A448, PYRB_PELCD ;  Q3B5K1, PYRB_PELLD ;  B4SCQ7, PYRB_PELPB ;
DR   A1AS13, PYRB_PELPD ;  A5D1A5, PYRB_PELTS ;  Q4FLQ4, PYRB_PELUB ;
DR   Q7MZ16, PYRB_PHOLL ;  Q6LUX0, PYRB_PHOPR ;  Q6L0F2, PYRB_PICTO ;
DR   A1VSL4, PYRB_POLNA ;  Q12EE6, PYRB_POLSJ ;  A4SVF3, PYRB_POLSQ ;
DR   Q7MX58, PYRB_PORGI ;  B4S9J4, PYRB_PROA2 ;  Q6A917, PYRB_PROAC ;
DR   A3PAV3, PYRB_PROM0 ;  A2C066, PYRB_PROM1 ;  A8G2P1, PYRB_PROM2 ;
DR   A2CCB6, PYRB_PROM3 ;  A9BDK0, PYRB_PROM4 ;  A2BUL3, PYRB_PROM5 ;
DR   Q31CU8, PYRB_PROM9 ;  Q7VDV6, PYRB_PROMA ;  B4F2M2, PYRB_PROMH ;
DR   Q7V4X7, PYRB_PROMM ;  Q7V355, PYRB_PROMP ;  A2BP31, PYRB_PROMS ;
DR   Q46HE0, PYRB_PROMT ;  A4SDL1, PYRB_PROVI ;  Q48P93, PYRB_PSE14 ;
DR   A6UYL2, PYRB_PSEA7 ;  B7V3Y9, PYRB_PSEA8 ;  Q02U10, PYRB_PSEAB ;
DR   Q59653, PYRB_PSEAE ;  Q1I3U2, PYRB_PSEE4 ;  Q4K4E2, PYRB_PSEF5 ;
DR   P56585, PYRB_PSEFA ;  C3K3K2, PYRB_PSEFS ;  A4XPA4, PYRB_PSEMY ;
DR   A5WA32, PYRB_PSEP1 ;  Q3K5A3, PYRB_PSEPF ;  B0KM23, PYRB_PSEPG ;
DR   Q88D30, PYRB_PSEPK ;  Q59711, PYRB_PSEPU ;  B1J355, PYRB_PSEPW ;
DR   Q87V99, PYRB_PSESM ;  Q4ZZ70, PYRB_PSEU2 ;  A4VRI1, PYRB_PSEU5 ;
DR   Q4FUA5, PYRB_PSYA2 ;  Q1QDD9, PYRB_PSYCK ;  A1SZR6, PYRB_PSYIN ;
DR   Q934T0, PYRB_PSYT1 ;  A5WGK5, PYRB_PSYWF ;  P77918, PYRB_PYRAB ;
DR   Q8ZYH7, PYRB_PYRAE ;  A4WGX8, PYRB_PYRAR ;  A3MY52, PYRB_PYRCJ ;
DR   Q8U373, PYRB_PYRFU ;  O58451, PYRB_PYRHO ;  A1RTF7, PYRB_PYRIL ;
DR   Q5JHM9, PYRB_PYRKO ;  Q1LJR3, PYRB_RALME ;  B2U7B1, PYRB_RALPJ ;
DR   Q8Y1L2, PYRB_RALSO ;  A9WSB2, PYRB_RENSM ;  B3PW37, PYRB_RHIE6 ;
DR   Q2K9P5, PYRB_RHIEC ;  Q1MIH6, PYRB_RHIL3 ;  Q98M86, PYRB_RHILO ;
DR   B5ZYQ2, PYRB_RHILW ;  Q92QL5, PYRB_RHIME ;  C3MA97, PYRB_RHISN ;
DR   Q7UNR3, PYRB_RHOBA ;  B6IN31, PYRB_RHOCS ;  C0ZZC3, PYRB_RHOE4 ;
DR   Q21YN9, PYRB_RHOFD ;  C1B4I7, PYRB_RHOOB ;  Q2IXD1, PYRB_RHOP2 ;
DR   Q07L79, PYRB_RHOP5 ;  Q6N565, PYRB_RHOPA ;  Q215Y5, PYRB_RHOPB ;
DR   Q135I5, PYRB_RHOPS ;  B3Q9X4, PYRB_RHOPT ;  Q2RPG0, PYRB_RHORT ;
DR   A3PN48, PYRB_RHOS1 ;  Q3IZ49, PYRB_RHOS4 ;  A4WP19, PYRB_RHOS5 ;
DR   B9KNE8, PYRB_RHOSK ;  Q0S0M4, PYRB_RHOSR ;  A7NLW6, PYRB_ROSCS ;
DR   Q163C5, PYRB_ROSDO ;  A5UX78, PYRB_ROSS1 ;  Q1AVY6, PYRB_RUBXD ;
DR   A1AV91, PYRB_RUTMC ;  Q21I34, PYRB_SACD2 ;  A4FBG1, PYRB_SACEN ;
DR   B5F446, PYRB_SALA4 ;  A8LY14, PYRB_SALAI ;  A9MEW2, PYRB_SALAR ;
DR   Q57GE1, PYRB_SALCH ;  B5FSF3, PYRB_SALDC ;  B5R1I6, PYRB_SALEP ;
DR   B5R9J9, PYRB_SALG2 ;  B4TG41, PYRB_SALHS ;  B4T3K6, PYRB_SALNS ;
DR   Q5PJB2, PYRB_SALPA ;  A9N659, PYRB_SALPB ;  C0Q7B8, PYRB_SALPC ;
DR   B5BKQ9, PYRB_SALPK ;  Q2S2X3, PYRB_SALRD ;  B4TT83, PYRB_SALSV ;
DR   P0A1Z5, PYRB_SALTI ;  A4X615, PYRB_SALTO ;  P0A1Z4, PYRB_SALTY ;
DR   P19910, PYRB_SERMA ;  A8G961, PYRB_SERP5 ;  B2TYZ8, PYRB_SHIB3 ;
DR   Q31TI1, PYRB_SHIBS ;  Q328U0, PYRB_SHIDS ;  Q0SXI6, PYRB_SHIF8 ;
DR   P0A789, PYRB_SHIFL ;  Q3YUA6, PYRB_SHISS ;  Q5LX75, PYRB_SILPO ;
DR   A6U811, PYRB_SINMW ;  Q2NR35, PYRB_SODGM ;  Q01V56, PYRB_SOLUE ;
DR   A9GWW0, PYRB_SORC5 ;  Q1GUN0, PYRB_SPHAL ;  A5V3V4, PYRB_SPHWW ;
DR   A7X1E9, PYRB_STAA1 ;  A6U119, PYRB_STAA2 ;  Q2FHN8, PYRB_STAA3 ;
DR   Q2FZ75, PYRB_STAA8 ;  A5IS85, PYRB_STAA9 ;  Q5HGN2, PYRB_STAAC ;
DR   A6QGA1, PYRB_STAAE ;  P65617, PYRB_STAAM ;  P65618, PYRB_STAAN ;
DR   Q6GHN5, PYRB_STAAR ;  Q6GA13, PYRB_STAAS ;  A8Z3N7, PYRB_STAAT ;
DR   P65619, PYRB_STAAW ;  B9DPM9, PYRB_STACT ;  Q5HPZ1, PYRB_STAEQ ;
DR   Q8CPJ7, PYRB_STAES ;  Q4L5Q2, PYRB_STAHJ ;  A3DM48, PYRB_STAMF ;
DR   Q49WY1, PYRB_STAS1 ;  Q3K148, PYRB_STRA1 ;  Q8E5F3, PYRB_STRA3 ;
DR   Q8DZQ5, PYRB_STRA5 ;  Q827R1, PYRB_STRAW ;  Q9KXR2, PYRB_STRCO ;
DR   C0M758, PYRB_STRE4 ;  B4U3B0, PYRB_STREM ;  A8AX88, PYRB_STRGC ;
DR   B1W459, PYRB_STRGG ;  B4SMH0, PYRB_STRM5 ;  B2FRV3, PYRB_STRMK ;
DR   Q8DUP5, PYRB_STRMU ;  P65620, PYRB_STRP1 ;  Q04K46, PYRB_STRP2 ;
DR   P0DC84, PYRB_STRP3 ;  B5E514, PYRB_STRP4 ;  Q5XCR9, PYRB_STRP6 ;
DR   C1C7Q5, PYRB_STRP7 ;  Q8P1G1, PYRB_STRP8 ;  Q1JCE8, PYRB_STRPB ;
DR   Q1JMC8, PYRB_STRPC ;  Q1JHH2, PYRB_STRPD ;  Q1J794, PYRB_STRPF ;
DR   A2RF62, PYRB_STRPG ;  B1IC67, PYRB_STRPI ;  B8ZJU1, PYRB_STRPJ ;
DR   Q48U71, PYRB_STRPM ;  Q97QE2, PYRB_STRPN ;  P0DC85, PYRB_STRPQ ;
DR   B2IQ69, PYRB_STRPS ;  B5XKW0, PYRB_STRPZ ;  Q8DPH9, PYRB_STRR6 ;
DR   A4W0R0, PYRB_STRS2 ;  C0ME83, PYRB_STRS7 ;  A3CNI7, PYRB_STRSV ;
DR   A4VUG7, PYRB_STRSY ;  Q5M0X1, PYRB_STRT1 ;  Q5M5F8, PYRB_STRT2 ;
DR   Q03LU0, PYRB_STRTD ;  B9DU62, PYRB_STRU0 ;  C1CEN1, PYRB_STRZJ ;
DR   C1CL11, PYRB_STRZP ;  C1CR29, PYRB_STRZT ;  Q55338, PYRB_SULAC ;
DR   Q30TD9, PYRB_SULDN ;  C3N688, PYRB_SULIA ;  C4KHQ2, PYRB_SULIK ;
DR   C3MQG7, PYRB_SULIL ;  C3MW45, PYRB_SULIM ;  C3NGZ9, PYRB_SULIN ;
DR   C3NEP5, PYRB_SULIY ;  A6QC00, PYRB_SULNB ;  Q9UX08, PYRB_SULSO ;
DR   Q970X2, PYRB_SULTO ;  Q67Q01, PYRB_SYMTH ;  Q2LVI4, PYRB_SYNAS ;
DR   Q31QG7, PYRB_SYNE7 ;  A0LK21, PYRB_SYNFM ;  Q2JTU8, PYRB_SYNJA ;
DR   Q2JKC1, PYRB_SYNJB ;  Q5N3S1, PYRB_SYNP6 ;  A5GIK5, PYRB_SYNPW ;
DR   Q7U9G2, PYRB_SYNPX ;  A5GW48, PYRB_SYNR3 ;  Q0ID96, PYRB_SYNS3 ;
DR   Q3AUM3, PYRB_SYNS9 ;  Q3AMW4, PYRB_SYNSC ;  Q0AXG1, PYRB_SYNWW ;
DR   P74163, PYRB_SYNY3 ;  Q9HKM2, PYRB_THEAC ;  P96079, PYRB_THEAQ ;
DR   Q8DIM4, PYRB_THEEB ;  Q47R25, PYRB_THEFY ;  C5A2H1, PYRB_THEGJ ;
DR   P96111, PYRB_THEMA ;  B1Y9R0, PYRB_THENV ;  B6YXW4, PYRB_THEON ;
DR   A1RZC5, PYRB_THEPD ;  Q72KU0, PYRB_THET2 ;  Q5SK66, PYRB_THET8 ;
DR   Q8R9R5, PYRB_THETN ;  Q97B29, PYRB_THEVO ;  Q31EK2, PYRB_THICR ;
DR   Q3SFS1, PYRB_THIDA ;  C4LBX2, PYRB_TOLAT ;  Q04595, PYRB_TREDE ;
DR   Q10WL4, PYRB_TRIEI ;  Q0W5I2, PYRB_UNCMA ;  B1GYY8, PYRB_UNCTG ;
DR   C5CL68, PYRB_VARPS ;  A1WI17, PYRB_VEREI ;  A5CXW7, PYRB_VESOH ;
DR   A5F5C9, PYRB_VIBC3 ;  Q9KP66, PYRB_VIBCH ;  Q5E7U5, PYRB_VIBF1 ;
DR   B5F9P9, PYRB_VIBFM ;  A7MSE0, PYRB_VIBHB ;  Q87LF8, PYRB_VIBPA ;
DR   P96174, PYRB_VIBS2 ;  Q8DCF6, PYRB_VIBVU ;  Q7MHF1, PYRB_VIBVY ;
DR   Q8D293, PYRB_WIGBR ;  Q73GP1, PYRB_WOLPM ;  B3CLL6, PYRB_WOLPP ;
DR   Q7M9Y9, PYRB_WOLSU ;  Q5GSQ1, PYRB_WOLTR ;  C0R3U0, PYRB_WOLWR ;
DR   Q8PII1, PYRB_XANAC ;  Q3BR21, PYRB_XANC5 ;  Q4UWY7, PYRB_XANC8 ;
DR   B0RQN0, PYRB_XANCB ;  Q8P767, PYRB_XANCP ;  Q2P5W1, PYRB_XANOM ;
DR   Q5H2Z0, PYRB_XANOR ;  A7IMA0, PYRB_XANP2 ;  Q9PBB8, PYRB_XYLFA ;
DR   Q87C22, PYRB_XYLFT ;  A1JRD5, PYRB_YERE8 ;  A7FDV1, PYRB_YERP3 ;
DR   Q1C1J5, PYRB_YERPA ;  B2K421, PYRB_YERPB ;  Q8ZB39, PYRB_YERPE ;
DR   A9R1U2, PYRB_YERPG ;  Q1CDY3, PYRB_YERPN ;  A4THG6, PYRB_YERPP ;
DR   Q665I6, PYRB_YERPS ;  B1JKJ8, PYRB_YERPY ;  Q5NPE5, PYRB_ZYMMO ;
//
ID   2.1.3.3
DE   Ornithine carbamoyltransferase.
AN   Citrulline phosphorylase.
AN   Ornithine transcarbamylase.
AN   OTC.
AN   OTCase.
CA   Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.
CC   -!- The plant enzyme also catalyzes the reactions of EC 2.1.3.6,
CC       EC 2.7.2.2 and EC 3.5.3.12, thus acting as putrescine synthase,
CC       converting agmatine and ornithine into putrescine and citrulline
CC       respectively.
PR   PROSITE; PDOC00091;
DR   P04391, OTC1_ECOLI ;  Q02047, OTC1_PSESH ;  P06960, OTC2_ECOLI ;
DR   P68746, OTC2_PSESF ;  P68747, OTC2_PSESH ;  Q8CU41, OTCC1_STAES;
DR   P65603, OTCC1_STRA3;  P65604, OTCC1_STRA5;  Q8CMW2, OTCC2_STAES;
DR   P65605, OTCC2_STRA3;  P65606, OTCC2_STRA5;  P11726, OTCC_AERPU ;
DR   Q73E86, OTCC_BACC1 ;  Q81II0, OTCC_BACCR ;  Q6HP28, OTCC_BACHK ;
DR   O86132, OTCC_BACLD ;  O51897, OTCC_BORAF ;  O51782, OTCC_BORBU ;
DR   Q65ZT0, OTCC_BORGA ;  Q62KD8, OTCC_BURMA ;  Q63U72, OTCC_BURPS ;
DR   Q7NRK0, OTCC_CHRVO ;  Q0TUR4, OTCC_CLOP1 ;  P0C2E4, OTCC_CLOPE ;
DR   Q8FAE1, OTCC_ECOL6 ;  Q839Q5, OTCC_ENTFA ;  Q9ZIX8, OTCC_HAEGA ;
DR   P44770, OTCC_HAEIN ;  Q48296, OTCC_HALSA ;  Q8G998, OTCC_LACHI ;
DR   P0C2U0, OTCC_LACLA ;  P0C2U1, OTCC_LACLC ;  Q9K575, OTCC_LACLM ;
DR   O53089, OTCC_LACSK ;  P59779, OTCC_MYCCC ;  Q8EVF5, OTCC_MYCPE ;
DR   P75473, OTCC_MYCPN ;  Q8VW55, OTCC_OENOE ;  Q6LUW9, OTCC_PHOPR ;
DR   P08308, OTCC_PSEAE ;  Q936V7, OTCC_PSEME ;  Q88P53, OTCC_PSEPK ;
DR   P11727, OTCC_PSEPU ;  O31018, OTCC_RHIET ;  Q92ZT1, OTCC_RHIME ;
DR   Q8Z127, OTCC_SALTI ;  Q8ZK35, OTCC_SALTY ;  Q5HCR3, OTCC_STAAC ;
DR   P65601, OTCC_STAAM ;  P65602, OTCC_STAAN ;  Q6GDG8, OTCC_STAAR ;
DR   Q6G640, OTCC_STAAS ;  Q8NUK8, OTCC_STAAW ;  Q8RP83, OTCC_STRAG ;
DR   Q8GND4, OTCC_STRGC ;  P0C0D0, OTCC_STRP1 ;  P0DC82, OTCC_STRP3 ;
DR   Q5XAY4, OTCC_STRP6 ;  P65610, OTCC_STRP8 ;  P65607, OTCC_STRPN ;
DR   P0DC83, OTCC_STRPQ ;  P0C0C9, OTCC_STRPY ;  P65608, OTCC_STRR6 ;
DR   Q6TK73, OTCC_STRRT ;  Q8GG79, OTCC_STRSU ;  Q9HIK9, OTCC_THEAC ;
DR   Q97C32, OTCC_THEVO ;  Q73P70, OTCC_TREDE ;  A1TLB7, OTC_ACIAC  ;
DR   Q6FCH8, OTC_ACIAD  ;  A3M663, OTC_ACIBT  ;  B0V6G5, OTC_ACIBY  ;
DR   A0LUC1, OTC_ACIC1  ;  A3N1W5, OTC_ACTP2  ;  B3GY96, OTC_ACTP7  ;
DR   B0BQQ2, OTC_ACTPJ  ;  A0KQG4, OTC_AERHH  ;  Q9YAE7, OTC_AERPE  ;
DR   A4SHP4, OTC_AERS4  ;  Q8UI70, OTC_AGRT5  ;  B2UML6, OTC_AKKM8  ;
DR   A6TWW1, OTC_ALKMQ  ;  Q3MB19, OTC_ANAVT  ;  B7GM02, OTC_ANOFW  ;
DR   O67607, OTC_AQUAE  ;  O50039, OTC_ARATH  ;  O29013, OTC_ARCFU  ;
DR   Q5P0Z8, OTC_AROAE  ;  P11066, OTC_ASPNG  ;  P0C2P2, OTC_ASPTE  ;
DR   P0C2P3, OTC_ASPTN  ;  A1K7J9, OTC_AZOSB  ;  C3P7R4, OTC_BACAA  ;
DR   C3LJQ5, OTC_BACAC  ;  Q81M99, OTC_BACAN  ;  Q731G7, OTC_BACC1  ;
DR   C1ER02, OTC_BACC3  ;  B7HNP5, OTC_BACC7  ;  B9IXC5, OTC_BACCQ  ;
DR   Q818W3, OTC_BACCR  ;  Q635F4, OTC_BACCZ  ;  Q9K8V8, OTC_BACHD  ;
DR   Q6HE32, OTC_BACHK  ;  P18186, OTC_BACSU  ;  P59778, OTC_BIFLO  ;
DR   B7GTP2, OTC_BIFLS  ;  Q7VQT3, OTC_BLOFL  ;  Q2KZD0, OTC_BORA1  ;
DR   Q0SM07, OTC_BORAP  ;  Q7WKW6, OTC_BORBR  ;  B7J0T6, OTC_BORBZ  ;
DR   Q7W7H7, OTC_BORPA  ;  Q7VTJ8, OTC_BORPE  ;  Q9N1U7, OTC_BOVIN  ;
DR   Q89VE8, OTC_BRAJA  ;  Q2YPH2, OTC_BRUA2  ;  Q57F56, OTC_BRUAB  ;
DR   Q8YFA2, OTC_BRUME  ;  A5VNP2, OTC_BRUO2  ;  Q8G2L7, OTC_BRUSU  ;
DR   B8D9F3, OTC_BUCA5  ;  P57449, OTC_BUCAI  ;  P59100, OTC_BUCAP  ;
DR   B8D7Q5, OTC_BUCAT  ;  Q89AG1, OTC_BUCBP  ;  Q1BU60, OTC_BURCA  ;
DR   A0K9X6, OTC_BURCH  ;  B4E9G6, OTC_BURCJ  ;  Q62M76, OTC_BURMA  ;
DR   Q63WM2, OTC_BURPS  ;  Q39DI7, OTC_BURS3  ;  A4XLM2, OTC_CALS8  ;
DR   A7ZCL8, OTC_CAMC1  ;  A7GZL8, OTC_CAMC5  ;  A0RR73, OTC_CAMFF  ;
DR   A7I3W8, OTC_CAMHC  ;  A8FM43, OTC_CAMJ8  ;  A7H345, OTC_CAMJD  ;
DR   Q9PNU6, OTC_CAMJE  ;  A1VZY2, OTC_CAMJJ  ;  Q5HUG8, OTC_CAMJR  ;
DR   Q3A9W4, OTC_CARHZ  ;  Q9A653, OTC_CAUCR  ;  A0RUE9, OTC_CENSY  ;
DR   Q9YHY9, OTC_CHICK  ;  Q8KDE2, OTC_CHLTE  ;  Q1QVM7, OTC_CHRSD  ;
DR   Q7NWJ6, OTC_CHRVO  ;  A5CSJ2, OTC_CLAM3  ;  B0RHD4, OTC_CLAMS  ;
DR   Q97M82, OTC_CLOAB  ;  A7FWM4, OTC_CLOB1  ;  C3L179, OTC_CLOB6  ;
DR   A5I524, OTC_CLOBH  ;  C1FTE9, OTC_CLOBJ  ;  B1IJJ6, OTC_CLOBK  ;
DR   A7GGI0, OTC_CLOBL  ;  B1KXQ3, OTC_CLOBM  ;  Q0SWK5, OTC_CLOPS  ;
DR   P0CL21, OTC_COCIM  ;  Q6NHG6, OTC_CORDI  ;  Q8FTN1, OTC_COREF  ;
DR   Q59283, OTC_CORGL  ;  Q46XK9, OTC_CUPPJ  ;  B3R6D6, OTC_CUPTR  ;
DR   Q47BL9, OTC_DECAR  ;  Q9RY70, OTC_DEIRA  ;  Q30YB7, OTC_DESDG  ;
DR   Q6AR58, OTC_DESPS  ;  Q72D35, OTC_DESVH  ;  A1VEP9, OTC_DESVV  ;
DR   A7ZVD3, OTC_ECO24  ;  B7MLQ9, OTC_ECO45  ;  B7LCW4, OTC_ECO55  ;
DR   Q8XCB8, OTC_ECO57  ;  B7M9L3, OTC_ECO8A  ;  A8A810, OTC_ECOHS  ;
DR   Q0T9E0, OTC_ECOL5  ;  Q8FAD6, OTC_ECOL6  ;  B1ISV4, OTC_ECOLC  ;
DR   B7NGI6, OTC_ECOLU  ;  P11803, OTC_EMENI  ;  Q6DA71, OTC_ERWCT  ;
DR   B2VL36, OTC_ERWT9  ;  A8LE44, OTC_FRASN  ;  Q39Z73, OTC_GEOMG  ;
DR   Q9ZB62, OTC_GEOSE  ;  Q74GU2, OTC_GEOSL  ;  Q7NGR7, OTC_GLOVI  ;
DR   Q7VP68, OTC_HAEDU  ;  A5UHA3, OTC_HAEIG  ;  A1WUZ6, OTC_HALHL  ;
DR   Q18E28, OTC_HALWD  ;  Q7VHJ0, OTC_HELHP  ;  A4G3H2, OTC_HERAR  ;
DR   P00480, OTC_HUMAN  ;  A2BM26, OTC_HYPBU  ;  Q0C4M2, OTC_HYPNA  ;
DR   A8ACB1, OTC_IGNH4  ;  Q03NY9, OTC_LACBA  ;  Q9CHD1, OTC_LACLA  ;
DR   O08322, OTC_LACPL  ;  A5VIM0, OTC_LACRD  ;  B2G653, OTC_LACRJ  ;
DR   Q6AGC9, OTC_LEIXX  ;  Q72T26, OTC_LEPIC  ;  Q8F2D1, OTC_LEPIN  ;
DR   Q92BC1, OTC_LISIN  ;  Q71Z80, OTC_LISMF  ;  B8DHF4, OTC_LISMH  ;
DR   Q8Y6U5, OTC_LISMO  ;  Q65TN0, OTC_MANSM  ;  A1U324, OTC_MARAV  ;
DR   A6UTW9, OTC_META3  ;  Q8TKT5, OTC_METAC  ;  Q465R0, OTC_METBF  ;
DR   Q606D8, OTC_METCA  ;  Q1H0L0, OTC_METFK  ;  Q2FPP7, OTC_METHJ  ;
DR   Q58291, OTC_METJA  ;  Q8TWG4, OTC_METKA  ;  A2SQ85, OTC_METLZ  ;
DR   A4FYS5, OTC_METM5  ;  A6VJK4, OTC_METM7  ;  Q8Q0J1, OTC_METMA  ;
DR   A3CU82, OTC_METMJ  ;  Q6LZS1, OTC_METMP  ;  A5UMK3, OTC_METS3  ;
DR   Q2NI83, OTC_METST  ;  O27495, OTC_METTH  ;  A6UNM1, OTC_METVS  ;
DR   Q9K4Y9, OTC_MORAB  ;  Q9K4Z4, OTC_MORPR  ;  P11725, OTC_MOUSE  ;
DR   A0QHB0, OTC_MYCA1  ;  P0A5M9, OTC_MYCBO  ;  A1KJ73, OTC_MYCBP  ;
DR   A4T9W6, OTC_MYCGI  ;  Q9CC11, OTC_MYCLE  ;  Q740I5, OTC_MYCPA  ;
DR   A0QYS8, OTC_MYCS2  ;  A5U313, OTC_MYCTA  ;  P0A5M8, OTC_MYCTU  ;
DR   A0PP77, OTC_MYCUA  ;  O86376, OTC_NEIAN  ;  Q01322, OTC_NEICI  ;
DR   Q9R3D1, OTC_NEIEL  ;  Q01323, OTC_NEIFL  ;  O86385, OTC_NEIFV  ;
DR   Q5F7E6, OTC_NEIG1  ;  P21302, OTC_NEIGO  ;  Q01324, OTC_NEILA  ;
DR   Q9JTI4, OTC_NEIMA  ;  P0DH57, OTC_NEIMB  ;  Q01325, OTC_NEIME  ;
DR   A1KUZ7, OTC_NEIMF  ;  E6N013, OTC_NEIMH  ;  Q01326, OTC_NEIMU  ;
DR   O86404, OTC_NEIPE  ;  O86408, OTC_NEIPH  ;  Q01327, OTC_NEIPO  ;
DR   O86412, OTC_NEISI  ;  O86415, OTC_NEISU  ;  Q0AEE3, OTC_NITEC  ;
DR   Q82UP4, OTC_NITEU  ;  Q1QQG6, OTC_NITHX  ;  Q3J8G0, OTC_NITOC  ;
DR   A6Q1W6, OTC_NITSB  ;  Q3SVB0, OTC_NITWN  ;  O87319, OTC_NOSP7  ;
DR   Q8YMM6, OTC_NOSS1  ;  Q2G3J8, OTC_NOVAD  ;  Q8ET05, OTC_OCEIH  ;
DR   P14995, OTC_PACTA  ;  A1B3N7, OTC_PARDP  ;  P57876, OTC_PASMU  ;
DR   Q43814, OTC_PEA    ;  Q03DS0, OTC_PEDPA  ;  Q3A1V3, OTC_PELCD  ;
DR   A1ATU5, OTC_PELPD  ;  Q7MZ18, OTC_PHOLL  ;  Q6LG09, OTC_PHOPR  ;
DR   Q6L135, OTC_PICTO  ;  O19072, OTC_PIG    ;  Q6AA77, OTC_PROAC  ;
DR   Q319M8, OTC_PROM9  ;  Q7VAW6, OTC_PROMA  ;  Q7V8G9, OTC_PROMM  ;
DR   Q7V0J3, OTC_PROMP  ;  P11724, OTC_PSEAE  ;  Q88NX4, OTC_PSEPK  ;
DR   Q87XL4, OTC_PSESM  ;  Q4FT48, OTC_PSYA2  ;  Q1QAR3, OTC_PSYCK  ;
DR   A5WDJ2, OTC_PSYWF  ;  O93656, OTC_PYRAB  ;  Q8ZW40, OTC_PYRAE  ;
DR   A3MWJ5, OTC_PYRCJ  ;  Q51742, OTC_PYRFU  ;  O58457, OTC_PYRHO  ;
DR   A1RVH4, OTC_PYRIL  ;  Q5JI16, OTC_PYRKO  ;  Q1LJA1, OTC_RALME  ;
DR   B2UBA4, OTC_RALPJ  ;  Q8XWC0, OTC_RALSO  ;  P31326, OTC_RANCA  ;
DR   P00481, OTC_RAT    ;  A9WQ88, OTC_RENSM  ;  Q1MLV9, OTC_RHIL3  ;
DR   Q98BB6, OTC_RHILO  ;  Q92S99, OTC_RHIME  ;  Q7UQZ6, OTC_RHOBA  ;
DR   C1ASZ8, OTC_RHOOB  ;  Q07GY2, OTC_RHOP5  ;  Q6N0J0, OTC_RHOPA  ;
DR   A3PHL6, OTC_RHOS1  ;  Q3J4X5, OTC_RHOS4  ;  B9KMW0, OTC_RHOSK  ;
DR   Q0SI56, OTC_RHOSR  ;  Q169P2, OTC_ROSDO  ;  A1AWA3, OTC_RUTMC  ;
DR   Q8Z123, OTC_SALTI  ;  Q08016, OTC_SALTY  ;  P31317, OTC_SCHPO  ;
DR   P84010, OTC_SHEEP  ;  Q8EK29, OTC_SHEON  ;  Q31TJ4, OTC_SHIBS  ;
DR   Q328S8, OTC_SHIDS  ;  Q0SXJ4, OTC_SHIF8  ;  Q83IM2, OTC_SHIFL  ;
DR   Q3YU98, OTC_SHISS  ;  Q5LUT9, OTC_SILPO  ;  Q1GIW7, OTC_SILST  ;
DR   A9ERU2, OTC_SORC5  ;  A5V656, OTC_SPHWW  ;  Q5HGR3, OTC_STAAC  ;
DR   A6QG68, OTC_STAAE  ;  P0A099, OTC_STAAM  ;  P99073, OTC_STAAN  ;
DR   Q6GHR7, OTC_STAAR  ;  Q6GA45, OTC_STAAS  ;  P0C6P3, OTC_STAAU  ;
DR   Q8NX44, OTC_STAAW  ;  P0C0N0, OTC_STAEP  ;  P0C0N1, OTC_STAES  ;
DR   Q4L9V8, OTC_STAHJ  ;  A3DL27, OTC_STAMF  ;  Q82KQ4, OTC_STRAW  ;
DR   Q93JF1, OTC_STRCO  ;  C0MBK6, OTC_STRE4  ;  B4U1S2, OTC_STREM  ;
DR   Q8DVC9, OTC_STRMU  ;  Q04I25, OTC_STRP2  ;  B5E3F8, OTC_STRP4  ;
DR   C1CAZ4, OTC_STRP7  ;  Q1JAR4, OTC_STRPB  ;  Q1JKW5, OTC_STRPC  ;
DR   Q1JFZ1, OTC_STRPD  ;  Q1J5Q6, OTC_STRPF  ;  A2RDJ1, OTC_STRPG  ;
DR   B1I9W1, OTC_STRPI  ;  B8ZPY8, OTC_STRPJ  ;  B2INH0, OTC_STRPS  ;
DR   B5XMC1, OTC_STRPZ  ;  A4W094, OTC_STRS2  ;  C0MD77, OTC_STRS7  ;
DR   A4VU03, OTC_STRSY  ;  B9DUY9, OTC_STRU0  ;  C1CHE7, OTC_STRZJ  ;
DR   C1CU67, OTC_STRZT  ;  Q4J8Z2, OTC_SULAC  ;  Q30TL4, OTC_SULDN  ;
DR   A6QC22, OTC_SULNB  ;  Q97ZM1, OTC_SULSO  ;  Q971Y3, OTC_SULTO  ;
DR   Q67JZ8, OTC_SYMTH  ;  Q2LT98, OTC_SYNAS  ;  Q935Y4, OTC_SYNE7  ;
DR   Q5N1N8, OTC_SYNP6  ;  Q7U5V5, OTC_SYNPX  ;  Q55497, OTC_SYNY3  ;
DR   Q8DJW4, OTC_THEEB  ;  Q47NE4, OTC_THEFY  ;  A8F7Z9, OTC_THELT  ;
DR   P96108, OTC_THEMA  ;  A5IN78, OTC_THEP1  ;  P96134, OTC_THET2  ;
DR   Q8RCA4, OTC_THETN  ;  Q31I95, OTC_THICR  ;  P78605, OTC_TRAHI  ;
DR   Q9KP68, OTC_VIBCH  ;  C3LR49, OTC_VIBCM  ;  Q5E7U4, OTC_VIBF1  ;
DR   A7MSD8, OTC_VIBHB  ;  Q87LF9, OTC_VIBPA  ;  P96172, OTC_VIBS2  ;
DR   Q8DCF5, OTC_VIBVU  ;  Q7MHF2, OTC_VIBVY  ;  Q7M8B5, OTC_WOLSU  ;
DR   P05150, OTC_YEAST  ;  A7FMM5, OTC_YERP3  ;  Q8ZBG8, OTC_YERPE  ;
DR   Q1CM06, OTC_YERPN  ;  A4TQQ1, OTC_YERPP  ;  Q66F14, OTC_YERPS  ;
//
ID   2.1.3.4
DE   Deleted entry.
//
ID   2.1.3.5
DE   Oxamate carbamoyltransferase.
AN   Oxamic transcarbamylase.
CA   Carbamoyl phosphate + oxamate = phosphate + oxalureate.
//
ID   2.1.3.6
DE   Putrescine carbamoyltransferase.
CA   Carbamoyl phosphate + putrescine = phosphate + N-carbamoylputrescine.
CC   -!- The plant enzyme also catalyzes the reactions of EC 2.1.3.3,
CC       EC 2.7.2.2 and EC 3.5.3.12, thus acting as putrescine synthase,
CC       converting agmatine and ornithine into putrescine and citrulline
CC       respectively.
DR   Q837U7, PTC_ENTFA  ;  Q03NG2, PTC_LACBA  ;  Q7B9Y6, PTC_LACBR  ;
DR   Q9CEY4, PTC_LACLA  ;  Q38ZL1, PTC_LACSS  ;  C1KV77, PTC_LISMC  ;
DR   Q725C8, PTC_LISMF  ;  Q8YAS7, PTC_LISMO  ;  Q2SRJ4, PTC_MYCCT  ;
DR   Q6MSR6, PTC_MYCMS  ;  Q03HM9, PTC_PEDPA  ;  Q8DW19, PTC_STRMU  ;
DR   B7S4N1, PTC_STRRT  ;
//
ID   2.1.3.7
DE   3-hydroxymethylcephem carbamoyltransferase.
CA   Carbamoyl phosphate + a 3-hydroxymethylceph-3-em-4-carboxylate =
CA   phosphate + a 3-carbamoyloxymethylcephem.
CC   -!- Acts on a wide range of 3-hydroxymethylcephems (a subclass of the
CC       cephalosporin antibiotics).
CC   -!- Activated by ATP.
//
ID   2.1.3.8
DE   Lysine carbamoyltransferase.
AN   Lysine transcarbamylase.
CA   Carbamoyl phosphate + L-lysine = phosphate + L-homocitrulline.
CC   -!- Not identical with EC 2.1.3.3.
//
ID   2.1.3.9
DE   N-acetylornithine carbamoyltransferase.
AN   Acetylornithine transcarbamylase.
AN   AOTC.
AN   N-acetylornithine transcarbamylase.
CA   Carbamoyl phosphate + N(2)-acetyl-L-ornithine = phosphate + N-acetyl-L-
CA   citrulline.
CC   -!- Differs from EC 2.1.3.3.
CC   -!- This enzyme replaces EC 2.1.3.3 in the canonic arginine biosynthetic
CC       pathway of several eubacteria and has no catalytic activity with
CC       L-ornithine as substrate.
PR   PROSITE; PDOC00091;
DR   Q8A1E9, AOTC_BACTN ;  Q8PK25, AOTC_XANAC ;  Q8P8J2, AOTC_XANCP ;
DR   Q9PEN0, AOTC_XYLFA ;  Q87EL4, AOTC_XYLFT ;
//
ID   2.1.3.10
DE   Malonyl-S-ACP:biotin-protein carboxyltransferase.
CA   A malonyl-[acyl-carrier protein] + a biotinyl-[protein] = an acetyl-
CA   [acyl-carrier protein] + a carboxybiotinyl-[protein].
CC   -!- Derived from the components MadC and MadD of the anaerobic bacterium
CC       Malonomonas rubra, this enzyme is a component of EC 4.1.1.89.
CC   -!- The carboxy group is transferred from malonate to the prosthetic
CC       group of the biotin protein (MadF) with retention of configuration.
CC   -!- Similar to EC 4.1.1.87, which forms part of the biotin-independent
CC       EC 4.1.1.88, this enzyme also follows on from EC 2.3.1.187,
CC       and results in the regeneration of the acetyl-[acyl-carrier protein].
PR   PROSITE; PDOC50980;
//
ID   2.1.3.11
DE   N-succinylornithine carbamoyltransferase.
AN   N-succinyl-L-ornithine transcarbamylase.
AN   SOTCase.
AN   Succinylornithine transcarbamylase.
CA   Carbamoyl phosphate + N(2)-succinyl-L-ornithine = phosphate + N-succinyl-
CA   L-citrulline.
CC   -!- Specific for N-succinyl-L-ornithine and cannot use either L-ornithine
CC       (see EC 2.1.3.3) or N-acetyl-L-ornithine (see EC 2.1.3.9) as
CC       substrate.
CC   -!- However, a single amino-acid substitution (Pro90Glu) is sufficient to
CC       switch the enzyme to one that uses N-acetyl-L-ornithine as substrate.
CC   -!- It is essential for de novo arginine biosynthesis in the obligate
CC       anaerobe Bacteroides fragilis, suggesting that this organism uses an
CC       alternative pathway for synthesizing arginine.
//
ID   2.1.4.1
DE   Glycine amidinotransferase.
AN   L-arginine:glycine amidinotransferase.
CA   L-arginine + glycine = L-ornithine + guanidinoacetate.
CC   -!- Canavanine can act instead of arginine.
CC   -!- Formerly EC 2.6.2.1.
DR   Q2HJ74, GATM_BOVIN ;  Q9I9K9, GATM_CHICK ;  Q6PH19, GATM_DANRE ;
DR   P50440, GATM_HUMAN ;  Q4R806, GATM_MACFA ;  Q9D964, GATM_MOUSE ;
DR   P50441, GATM_PIG   ;  Q5RFB9, GATM_PONAB ;  P50442, GATM_RAT   ;
DR   Q9IAJ6, GATM_XENLA ;  Q6P832, GATM_XENTR ;
//
ID   2.1.4.2
DE   Scyllo-inosamine-4-phosphate amidinotransferase.
AN   Inosamine-P amidinotransferase.
AN   Inosamine-phosphate amidinotransferase.
AN   L-arginine:inosamine phosphate amidinotransferase.
AN   L-arginine:inosamine-P-amidinotransferase.
CA   L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate = L-ornithine +
CA   1-guanidino-1-deoxy-scyllo-inositol 4-phosphate.
CC   -!- 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol 6-phosphate,
CC       streptamine phosphate and 2-deoxystreptamine phosphate can also act
CC       as acceptors.
CC   -!- Canavanine can act as donor.
DR   Q54258, STRB1_STRGA;  P08078, STRB1_STRGR;  Q54264, STRB2_STRGA;
DR   P29780, STRB2_STRGR;
//
ID   2.2.1.1
DE   Transketolase.
AN   Glycoaldehyde transferase.
CA   Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose
CA   5-phosphate + D-xylulose 5-phosphate.
CF   Thiamine diphosphate.
CC   -!- Wide specificity for both reactants, e.g. converts hydroxypyruvate
CC       and R-CHO into CO(2) and R-CHOH-CO-CH(2)OH.
CC   -!- Transketolase from Alcaligenes faecalis shows high activity with
CC       D-erythrose as acceptor.
PR   PROSITE; PDOC00635;
DR   O94039, TKT1_CANAL ;  P27302, TKT1_ECOLI ;  Q12630, TKT1_KLULA ;
DR   P57927, TKT1_PASMU ;  Q9KUP2, TKT1_VIBCH ;  Q5E7R1, TKT1_VIBF1 ;
DR   Q87LK8, TKT1_VIBPA ;  Q8DCA2, TKT1_VIBVU ;  Q7MHK7, TKT1_VIBVY ;
DR   P23254, TKT1_YEAST ;  P33570, TKT2_ECOLI ;  P57958, TKT2_PASMU ;
DR   Q9KLW7, TKT2_VIBCH ;  Q5DZP0, TKT2_VIBF1 ;  Q87GY4, TKT2_VIBPA ;
DR   Q8D6H8, TKT2_VIBVU ;  Q7MDD4, TKT2_VIBVY ;  P33315, TKT2_YEAST ;
DR   Q42677, TKT7_CRAPL ;  Q42675, TKTA_CRAPL ;  Q42676, TKTC_CRAPL ;
DR   P21725, TKTC_CUPNH ;  Q7SIC9, TKTC_MAIZE ;  Q58092, TKTC_METJA ;
DR   Q43848, TKTC_SOLTU ;  O20250, TKTC_SPIOL ;  Q2NL26, TKTL1_BOVIN;
DR   P51854, TKTL1_HUMAN;  Q4R6M8, TKTL1_MACFA;  Q99MX0, TKTL1_MOUSE;
DR   Q2NKZ4, TKTL2_BOVIN;  Q9H0I9, TKTL2_HUMAN;  Q9D4D4, TKTL2_MOUSE;
DR   Q58094, TKTN_METJA ;  P21726, TKTP_CUPNH ;  O67642, TKT_AQUAE  ;
DR   Q9KAD7, TKT_BACHD  ;  P45694, TKT_BACSU  ;  Q6B855, TKT_BOVIN  ;
DR   P57195, TKT_BUCAI  ;  Q8KA26, TKT_BUCAP  ;  Q89AY2, TKT_BUCBP  ;
DR   Q556J0, TKT_DICDI  ;  P43757, TKT_HAEIN  ;  P29401, TKT_HUMAN  ;
DR   Q60HC7, TKT_MACFA  ;  P40142, TKT_MOUSE  ;  P59956, TKT_MYCBO  ;
DR   P47312, TKT_MYCGE  ;  P46708, TKT_MYCLE  ;  P75611, TKT_MYCPN  ;
DR   O06811, TKT_MYCTU  ;  Q8YRU9, TKT_NOSS1  ;  Q5R1W6, TKT_PANTR  ;
DR   A6YB01, TKT_PHYPO  ;  P34736, TKT_PICST  ;  Q5R4C1, TKT_PONAB  ;
DR   P84540, TKT_POPEU  ;  P50137, TKT_RAT    ;  P58333, TKT_RHIME  ;
DR   P0CZ16, TKT_RHOCA  ;  D5AV94, TKT_RHOCB  ;  P29277, TKT_RHOSH  ;
DR   Q9URM2, TKT_SCHPO  ;  P56900, TKT_SINMW  ;  Q5HG77, TKT_STAAC  ;
DR   P66962, TKT_STAAM  ;  P99161, TKT_STAAN  ;  Q6GH64, TKT_STAAR  ;
DR   Q6G9L6, TKT_STAAS  ;  P66963, TKT_STAAW  ;  Q5HPJ9, TKT_STAEQ  ;
DR   Q8CPC7, TKT_STAES  ;  Q5XAK5, TKT_STRP6  ;  Q8NZX4, TKT_STRP8  ;
DR   P22976, TKT_STRPN  ;  O83571, TKT_TREPA  ;  P51010, TKT_XANFL  ;
//
ID   2.2.1.2
DE   Transaldolase.
AN   Dihydroxyacetone transferase.
AN   Glycerone transferase.
CA   Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose
CA   4-phosphate + D-fructose 6-phosphate.
PR   PROSITE; PDOC00741;
DR   Q81V33, TAL1_BACAN ;  Q81HW6, TAL1_BACCR ;  P17440, TAL1_CYBJA ;
DR   Q6D8W0, TAL1_ERWCT ;  P34214, TAL1_KLULA ;  Q927A3, TAL1_LISIN ;
DR   Q71W21, TAL1_LISMF ;  Q8Y3T8, TAL1_LISMO ;  Q57TP8, TAL1_SALCH ;
DR   Q5PDM6, TAL1_SALPA ;  O42700, TAL1_SCHPO ;  Q3Z606, TAL1_SHISS ;
DR   Q82M93, TAL1_STRAW ;  O88018, TAL1_STRCO ;  P15019, TAL1_YEAST ;
DR   Q81MY9, TAL2_BACAN ;  Q81B21, TAL2_BACCR ;  Q6D0B2, TAL2_ERWCT ;
DR   P66958, TAL2_LISIN ;  Q723W2, TAL2_LISMF ;  P66957, TAL2_LISMO ;
DR   P48983, TAL2_NOSP7 ;  P48993, TAL2_NOSS1 ;  Q57LN7, TAL2_SALCH ;
DR   Q5PCU4, TAL2_SALPA ;  Q3YZ89, TAL2_SHISS ;  Q829U5, TAL2_STRAW ;
DR   Q9XAC0, TAL2_STRCO ;  P53228, TAL2_YEAST ;  P17441, TAL3_CYBJA ;
DR   P0A869, TALA_ECO57 ;  P0A868, TALA_ECOL6 ;  P0A867, TALA_ECOLI ;
DR   Q9CKL0, TALA_PASMU ;  Q8Z4T0, TALA_SALTI ;  Q8ZN83, TALA_SALTY ;
DR   Q83QM8, TALA_SHIFL ;  P0A871, TALB_ECO57 ;  Q8FLD1, TALB_ECOL6 ;
DR   P0A870, TALB_ECOLI ;  Q9CKH9, TALB_PASMU ;  P66956, TALB_SALTI ;
DR   P66955, TALB_SALTY ;  P0A872, TALB_SHIFL ;  Q2TBL6, TALDO_BOVIN;
DR   P86071, TALDO_CAPAA;  P80427, TALDO_CARMA;  Q8VI73, TALDO_CRIGR;
DR   Q54UP4, TALDO_DICDI;  Q9W1G0, TALDO_DROME;  P37837, TALDO_HUMAN;
DR   Q93092, TALDO_MOUSE;  Q29593, TALDO_PIG  ;  Q9EQS0, TALDO_RAT  ;
DR   A1TKQ3, TAL_ACIAC  ;  A0LTY8, TAL_ACIC1  ;  C1F2H6, TAL_ACIC5  ;
DR   B9MDC2, TAL_ACIET  ;  A1W3W5, TAL_ACISJ  ;  A3MYD4, TAL_ACTP2  ;
DR   B3GZQ2, TAL_ACTP7  ;  B0BRM0, TAL_ACTPJ  ;  A6VLW0, TAL_ACTSZ  ;
DR   A4SK74, TAL_AERS4  ;  B9JAX6, TAL_AGRRK  ;  Q8U7I5, TAL_AGRT5  ;
DR   B9JST0, TAL_AGRVS  ;  B6ERE2, TAL_ALISL  ;  A6TK31, TAL_ALKMQ  ;
DR   A8MJZ5, TAL_ALKOO  ;  B4RX40, TAL_ALTMD  ;  B8JAM9, TAL_ANAD2  ;
DR   Q2IGW6, TAL_ANADE  ;  A7H783, TAL_ANADF  ;  B4UHE7, TAL_ANASK  ;
DR   B9MJS9, TAL_ANATD  ;  P51778, TAL_ANAVT  ;  O66520, TAL_AQUAE  ;
DR   B8H7N3, TAL_ARTCA  ;  A0JWQ6, TAL_ARTS2  ;  A7Z9T0, TAL_BACA2  ;
DR   Q73DH4, TAL_BACC1  ;  A7GLA6, TAL_BACCN  ;  Q63FX6, TAL_BACCZ  ;
DR   Q5LAU6, TAL_BACFN  ;  Q64R94, TAL_BACFR  ;  Q9K6E4, TAL_BACHD  ;
DR   Q6HNE4, TAL_BACHK  ;  A8FIE1, TAL_BACP2  ;  Q5WB47, TAL_BACSK  ;
DR   P19669, TAL_BACSU  ;  Q8A767, TAL_BACTN  ;  A6L5J5, TAL_BACV8  ;
DR   A1UR41, TAL_BARBK  ;  Q6G1W4, TAL_BARHE  ;  Q6FYL8, TAL_BARQU  ;
DR   A9IYY3, TAL_BART1  ;  Q1LU10, TAL_BAUCH  ;  Q6MRM6, TAL_BDEBA  ;
DR   Q7VRT4, TAL_BLOFL  ;  Q2KVT3, TAL_BORA1  ;  Q7WME6, TAL_BORBR  ;
DR   Q7WAY2, TAL_BORPA  ;  A9HYZ1, TAL_BORPD  ;  Q7VY99, TAL_BORPE  ;
DR   C0QVC8, TAL_BRAHW  ;  C0Z838, TAL_BREBN  ;  B2S7M9, TAL_BRUA1  ;
DR   Q2YLI1, TAL_BRUA2  ;  Q57B82, TAL_BRUAB  ;  A9M843, TAL_BRUC2  ;
DR   C0RF56, TAL_BRUMB  ;  Q8YJ42, TAL_BRUME  ;  A5VSE7, TAL_BRUO2  ;
DR   A9WWS9, TAL_BRUSI  ;  Q8FYQ9, TAL_BRUSU  ;  B8D8P5, TAL_BUCA5  ;
DR   P57194, TAL_BUCAI  ;  Q8KA27, TAL_BUCAP  ;  B8D6Z9, TAL_BUCAT  ;
DR   Q89AY3, TAL_BUCBP  ;  Q058B4, TAL_BUCCC  ;  B1YU93, TAL_BURA4  ;
DR   Q1BUS8, TAL_BURCA  ;  B1JW82, TAL_BURCC  ;  A0K9A9, TAL_BURCH  ;
DR   B4E6F9, TAL_BURCJ  ;  Q0BD43, TAL_BURCM  ;  A9AIJ8, TAL_BURM1  ;
DR   A3MHY5, TAL_BURM7  ;  Q62ID7, TAL_BURMA  ;  A1V2A0, TAL_BURMS  ;
DR   A3NSY2, TAL_BURP0  ;  Q3JUL7, TAL_BURP1  ;  A3N794, TAL_BURP6  ;
DR   B2JE74, TAL_BURP8  ;  B2T236, TAL_BURPP  ;  Q63W00, TAL_BURPS  ;
DR   Q39E45, TAL_BURS3  ;  Q2SZY3, TAL_BURTA  ;  A4JGM1, TAL_BURVG  ;
DR   Q142S4, TAL_BURXL  ;  A4XL36, TAL_CALS8  ;  A8FK69, TAL_CAMJ8  ;
DR   A7H591, TAL_CAMJD  ;  Q9PIL5, TAL_CAMJE  ;  A1VY04, TAL_CAMJJ  ;
DR   Q5HWI6, TAL_CAMJR  ;  Q3AFT3, TAL_CARHZ  ;  B8H6D3, TAL_CAUCN  ;
DR   Q9A2F1, TAL_CAUCR  ;  B0T583, TAL_CAUSK  ;  B3PDM9, TAL_CELJU  ;
DR   Q5L5I5, TAL_CHLAB  ;  Q3ANX8, TAL_CHLCH  ;  Q822J3, TAL_CHLCV  ;
DR   Q255E4, TAL_CHLFF  ;  B3EII6, TAL_CHLL2  ;  Q9PK80, TAL_CHLMU  ;
DR   B3QLU3, TAL_CHLP8  ;  B3EQ72, TAL_CHLPB  ;  A1BJV5, TAL_CHLPD  ;
DR   Q9Z998, TAL_CHLPN  ;  B3QRS6, TAL_CHLT3  ;  Q3KM49, TAL_CHLTA  ;
DR   Q8KGF8, TAL_CHLTE  ;  O84315, TAL_CHLTR  ;  Q1QZV1, TAL_CHRSD  ;
DR   Q97JD9, TAL_CLOAB  ;  A7FTH1, TAL_CLOB1  ;  C3KTY4, TAL_CLOB6  ;
DR   B2V0J9, TAL_CLOBA  ;  B2TKE5, TAL_CLOBB  ;  A5I1C9, TAL_CLOBH  ;
DR   C1FL18, TAL_CLOBJ  ;  B1IJR0, TAL_CLOBK  ;  A7GCY3, TAL_CLOBL  ;
DR   B1L010, TAL_CLOBM  ;  Q185K3, TAL_CLOD6  ;  B9E0C8, TAL_CLOK1  ;
DR   A5N6V9, TAL_CLOK5  ;  A0Q3L2, TAL_CLONN  ;  Q0TTA4, TAL_CLOP1  ;
DR   Q8XMJ6, TAL_CLOPE  ;  A9KPQ3, TAL_CLOPH  ;  Q0SV41, TAL_CLOPS  ;
DR   Q899F3, TAL_CLOTE  ;  Q47WR3, TAL_COLP3  ;  B5Y9V1, TAL_COPPD  ;
DR   Q0K979, TAL_CUPNH  ;  Q46ZK0, TAL_CUPPJ  ;  B3R1I4, TAL_CUPTR  ;
DR   Q11S31, TAL_CYTH3  ;  Q3Z6N2, TAL_DEHE1  ;  Q9RUP6, TAL_DEIRA  ;
DR   A9BXM7, TAL_DELAS  ;  B8FH38, TAL_DESAA  ;  C6C0W4, TAL_DESAD  ;
DR   C0QIA5, TAL_DESAH  ;  B1I6H9, TAL_DESAP  ;  B8FZ81, TAL_DESHD  ;
DR   Q24ML5, TAL_DESHY  ;  A8ZW56, TAL_DESOH  ;  Q6AR67, TAL_DESPS  ;
DR   A4J9C4, TAL_DESRM  ;  B8E200, TAL_DICTD  ;  A8LNY7, TAL_DINSH  ;
DR   C5B7L0, TAL_EDWI9  ;  Q2N908, TAL_ERYLH  ;  C4ZF71, TAL_EUBR3  ;
DR   B1YEL0, TAL_EXIS2  ;  C4KYW2, TAL_EXISA  ;  A7HME3, TAL_FERNB  ;
DR   A6GYG9, TAL_FLAPJ  ;  Q0RH18, TAL_FRAAA  ;  Q2JCG8, TAL_FRASC  ;
DR   A8KYS5, TAL_FRASN  ;  B5ED52, TAL_GEOBB  ;  Q5KUG6, TAL_GEOKA  ;
DR   B3E1K9, TAL_GEOLS  ;  Q39YD4, TAL_GEOMG  ;  B9M1X7, TAL_GEOSF  ;
DR   Q748M4, TAL_GEOSL  ;  C6E082, TAL_GEOSM  ;  C5D9P4, TAL_GEOSW  ;
DR   A4ITL5, TAL_GEOTN  ;  A5GBY8, TAL_GEOUR  ;  Q7NK81, TAL_GLOVI  ;
DR   Q7VP02, TAL_HAEDU  ;  Q4QLG9, TAL_HAEI8  ;  A5UCY0, TAL_HAEIE  ;
DR   A5UIP9, TAL_HAEIG  ;  P45055, TAL_HAEIN  ;  B8F5Q3, TAL_HAEPS  ;
DR   Q0I1U0, TAL_HAES1  ;  B0UV30, TAL_HAES2  ;  C4K4G2, TAL_HAMD5  ;
DR   B0TI77, TAL_HELMI  ;  B6JNZ3, TAL_HELP2  ;  Q1CRD7, TAL_HELPH  ;
DR   Q9ZJC5, TAL_HELPJ  ;  B2UVP1, TAL_HELPS  ;  P56108, TAL_HELPY  ;
DR   A9AZ03, TAL_HERA2  ;  B4U8P1, TAL_HYDS0  ;  Q0BX85, TAL_HYPNA  ;
DR   Q28TL3, TAL_JANSC  ;  B2GH92, TAL_KOCRD  ;  C5CGH2, TAL_KOSOT  ;
DR   Q88S98, TAL_LACPL  ;  Q6AF36, TAL_LEIXX  ;  B0SGW0, TAL_LEPBA  ;
DR   Q04T59, TAL_LEPBJ  ;  Q051I1, TAL_LEPBL  ;  B0SQ07, TAL_LEPBP  ;
DR   B1Y2Y8, TAL_LEPCP  ;  Q72RT8, TAL_LEPIC  ;  Q8F3W3, TAL_LEPIN  ;
DR   B1I057, TAL_LYSSC  ;  Q65PZ8, TAL_MANSM  ;  A1U1Y1, TAL_MARAV  ;
DR   Q0AQJ7, TAL_MARMM  ;  A6VYA4, TAL_MARMS  ;  Q11DE1, TAL_MESSB  ;
DR   A6UTP5, TAL_META3  ;  Q9S0X4, TAL_METAM  ;  Q602L8, TAL_METCA  ;
DR   Q1H0R4, TAL_METFK  ;  Q58370, TAL_METJA  ;  A4FWM6, TAL_METM5  ;
DR   A9AA06, TAL_METM6  ;  A6VGP5, TAL_METM7  ;  Q6LXP1, TAL_METMP  ;
DR   A2SKF9, TAL_METPP  ;  A6UPV2, TAL_METVS  ;  Q2RFV4, TAL_MOOTA  ;
DR   P59955, TAL_MYCBO  ;  A1KIN7, TAL_MYCBP  ;  C1AN93, TAL_MYCBT  ;
DR   B8ZUQ2, TAL_MYCLB  ;  P55193, TAL_MYCLE  ;  B2HP98, TAL_MYCMM  ;
DR   Q741B5, TAL_MYCPA  ;  A0QWX9, TAL_MYCS2  ;  A5U2F1, TAL_MYCTA  ;
DR   O06812, TAL_MYCTU  ;  A0PPP5, TAL_MYCUA  ;  Q1CZW4, TAL_MYXXD  ;
DR   B2A3J5, TAL_NATTJ  ;  Q5F6E9, TAL_NEIG1  ;  B4RJ66, TAL_NEIG2  ;
DR   A9M2N9, TAL_NEIM0  ;  Q9JSU1, TAL_NEIMA  ;  Q9K139, TAL_NEIMB  ;
DR   A1KVT3, TAL_NEIMF  ;  A9A413, TAL_NITMS  ;  B2J2D9, TAL_NOSP7  ;
DR   P58561, TAL_NOSS1  ;  Q2G5P7, TAL_NOVAD  ;  Q8CX76, TAL_OCEIH  ;
DR   A6WXW5, TAL_OCHA4  ;  B1ZUE6, TAL_OPITP  ;  A6LG93, TAL_PARD8  ;
DR   A1B4Z2, TAL_PARDP  ;  A7HT46, TAL_PARL1  ;  Q6MAI4, TAL_PARUW  ;
DR   Q3A7Y3, TAL_PELCD  ;  Q3B151, TAL_PELLD  ;  B4SH30, TAL_PELPB  ;
DR   A1AKQ8, TAL_PELPD  ;  A5CYD0, TAL_PELTS  ;  C0QPV2, TAL_PERMH  ;
DR   A9BHK7, TAL_PETMO  ;  B4RB97, TAL_PHEZH  ;  Q7N8Z1, TAL_PHOLL  ;
DR   Q6LLF0, TAL_PHOPR  ;  Q6L178, TAL_PICTO  ;  A1VJZ5, TAL_POLNA  ;
DR   Q12FI4, TAL_POLSJ  ;  B2RHK7, TAL_PORG3  ;  Q7MXG0, TAL_PORGI  ;
DR   B4S6D0, TAL_PROA2  ;  A3PBP3, TAL_PROM0  ;  A2C0X8, TAL_PROM1  ;
DR   A9BEE2, TAL_PROM4  ;  A2BVI1, TAL_PROM5  ;  Q31C15, TAL_PROM9  ;
DR   Q7VD64, TAL_PROMA  ;  B4F2V2, TAL_PROMH  ;  Q7V6B8, TAL_PROMM  ;
DR   Q7V2G1, TAL_PROMP  ;  Q46GQ7, TAL_PROMT  ;  A4SGX9, TAL_PROVI  ;
DR   Q48KH5, TAL_PSE14  ;  Q15PR4, TAL_PSEA6  ;  A6V3U3, TAL_PSEA7  ;
DR   B7UWP0, TAL_PSEA8  ;  Q02NV3, TAL_PSEAB  ;  Q9I047, TAL_PSEAE  ;
DR   Q1I7G7, TAL_PSEE4  ;  Q4KF90, TAL_PSEF5  ;  A4XTM7, TAL_PSEMY  ;
DR   Q3K9H0, TAL_PSEPF  ;  B0KHA7, TAL_PSEPG  ;  Q88KX1, TAL_PSEPK  ;
DR   B1J623, TAL_PSEPW  ;  Q884H4, TAL_PSESM  ;  Q4ZV64, TAL_PSEU2  ;
DR   A4VK43, TAL_PSEU5  ;  Q1LLK8, TAL_RALME  ;  B2U9W5, TAL_RALPJ  ;
DR   Q8Y014, TAL_RALSO  ;  A9WT40, TAL_RENSM  ;  B3Q0T5, TAL_RHIE6  ;
DR   Q2K414, TAL_RHIEC  ;  Q98EV0, TAL_RHILO  ;  B5ZQY2, TAL_RHILW  ;
DR   Q92LK3, TAL_RHIME  ;  C3M9S7, TAL_RHISN  ;  B6IPE0, TAL_RHOCS  ;
DR   Q21ZD6, TAL_RHOFD  ;  Q2RUN7, TAL_RHORT  ;  A3PLV0, TAL_RHOS1  ;
DR   Q3J0F0, TAL_RHOS4  ;  A4WRW1, TAL_RHOS5  ;  B9KKW2, TAL_RHOSK  ;
DR   A7NGG1, TAL_ROSCS  ;  Q168B1, TAL_ROSDO  ;  A5V243, TAL_ROSS1  ;
DR   A4FBP0, TAL_SACEN  ;  A1S414, TAL_SHEAM  ;  B8EFD7, TAL_SHEB2  ;
DR   A3D1F5, TAL_SHEB5  ;  A6WKC4, TAL_SHEB8  ;  A9L4T6, TAL_SHEB9  ;
DR   Q12KL3, TAL_SHEDO  ;  Q07Z25, TAL_SHEFN  ;  B0TJA0, TAL_SHEHH  ;
DR   A3QBW2, TAL_SHELP  ;  Q8EBH2, TAL_SHEON  ;  A8H1G4, TAL_SHEPA  ;
DR   A4Y494, TAL_SHEPC  ;  B8CSD3, TAL_SHEPW  ;  A0L002, TAL_SHESA  ;
DR   A8FSH3, TAL_SHESH  ;  Q0HFX9, TAL_SHESM  ;  Q0HS72, TAL_SHESR  ;
DR   A1RMN6, TAL_SHESW  ;  B1KIS4, TAL_SHEWM  ;  Q326L3, TAL_SHIBS  ;
DR   Q32KB0, TAL_SHIDS  ;  Q5LNS5, TAL_SILPO  ;  Q1GE05, TAL_SILST  ;
DR   A6UDM7, TAL_SINMW  ;  Q2NS86, TAL_SODGM  ;  A9GI16, TAL_SORC5  ;
DR   Q1GS53, TAL_SPHAL  ;  A5V2S4, TAL_SPHWW  ;  Q8E3B1, TAL_STRA3  ;
DR   Q8DXP1, TAL_STRA5  ;  C0M7L5, TAL_STRE4  ;  B4U4L6, TAL_STREM  ;
DR   P66959, TAL_STRP1  ;  P0DG12, TAL_STRP3  ;  Q5XAK4, TAL_STRP6  ;
DR   P66961, TAL_STRP8  ;  Q1JAF7, TAL_STRPB  ;  Q1JKK8, TAL_STRPC  ;
DR   Q1JFK0, TAL_STRPD  ;  Q1J5E9, TAL_STRPF  ;  A2RD32, TAL_STRPG  ;
DR   Q48RY1, TAL_STRPM  ;  P0DG13, TAL_STRPQ  ;  B5XMM1, TAL_STRPZ  ;
DR   C0MGU8, TAL_STRS7  ;  B2V7E1, TAL_SULSY  ;  Q67TE2, TAL_SYMTH  ;
DR   A0LEA2, TAL_SYNFM  ;  Q5N127, TAL_SYNP6  ;  Q7U5E8, TAL_SYNPX  ;
DR   Q0AUA5, TAL_SYNWW  ;  P72797, TAL_SYNY3  ;  C5BLR8, TAL_TERTT  ;
DR   B7IE29, TAL_THEAB  ;  Q9HKI3, TAL_THEAC  ;  Q8DLL7, TAL_THEEB  ;
DR   Q47ND3, TAL_THEFY  ;  A8F6A5, TAL_THELT  ;  A6LNG2, TAL_THEM4  ;
DR   Q9WYD1, TAL_THEMA  ;  A5IKB4, TAL_THEP1  ;  B0K6D2, TAL_THEPX  ;
DR   B1L9J1, TAL_THESQ  ;  Q72JR7, TAL_THET2  ;  Q5SJE8, TAL_THET8  ;
DR   Q8R8S6, TAL_THETN  ;  Q97AZ4, TAL_THEVO  ;  B5YHV2, TAL_THEYD  ;
DR   Q3SL03, TAL_THIDA  ;  B8GMX9, TAL_THISH  ;  Q118F4, TAL_TRIEI  ;
DR   C5CPN2, TAL_VARPS  ;  A1WIS6, TAL_VEREI  ;  A5F028, TAL_VIBC3  ;
DR   Q9KLW8, TAL_VIBCH  ;  C3LVN8, TAL_VIBCM  ;  Q5DZP1, TAL_VIBF1  ;
DR   B5EUF3, TAL_VIBFM  ;  A7N1Z7, TAL_VIBHB  ;  Q87GY5, TAL_VIBPA  ;
DR   Q8D6H9, TAL_VIBVU  ;  Q7MDD5, TAL_VIBVY  ;  Q8D1X3, TAL_WIGBR  ;
DR   Q8PNY6, TAL_XANAC  ;  Q3BX43, TAL_XANC5  ;  Q4UR79, TAL_XANC8  ;
DR   B0RUE4, TAL_XANCB  ;  Q8PCA4, TAL_XANCP  ;  Q2NZS1, TAL_XANOM  ;
DR   B2SQJ4, TAL_XANOP  ;  Q5GWL8, TAL_XANOR  ;  A1JJD0, TAL_YERE8  ;
DR   A7FME9, TAL_YERP3  ;  B2K3L5, TAL_YERPB  ;  Q8ZIN2, TAL_YERPE  ;
DR   A9R021, TAL_YERPG  ;  Q66ET5, TAL_YERPS  ;  B1JL09, TAL_YERPY  ;
//
ID   2.2.1.3
DE   Formaldehyde transketolase.
AN   DHAS.
AN   Dihydroxyacetone synthase.
AN   Glycerone synthase.
CA   D-xylulose 5-phosphate + formaldehyde = glyceraldehyde 3-phosphate +
CA   glycerone.
CF   Thiamine diphosphate.
CC   -!- Also converts hydroxypyruvate and formaldehyde into glycerone and
CC       CO(2).
CC   -!- Not identical with EC 2.2.1.1.
PR   PROSITE; PDOC00635;
DR   O93884, DAS_CANBO  ;  P06834, DAS_PICAN  ;
//
ID   2.2.1.4
DE   Acetoin--ribose-5-phosphate transaldolase.
AN   1-deoxy-D-altro-heptulose-7-phosphate synthetase.
CA   3-hydroxybutan-2-one + D-ribose 5-phosphate = acetaldehyde + 1-deoxy-D-
CA   altro-heptulose 7-phosphate.
CF   Thiamine diphosphate.
//
ID   2.2.1.5
DE   2-hydroxy-3-oxoadipate synthase.
AN   2-hydroxy-3-oxoadipate glyoxylate-lyase (carboxylating).
AN   2-hydroxy-3-oxoadipate synthetase.
AN   Alpha-ketoglutaric-glyoxylic carboligase.
AN   Oxoglutarate: glyoxylate carboligase.
CA   2-oxoglutarate + glyoxylate = 2-hydroxy-3-oxoadipate + CO(2).
CF   Thiamine diphosphate.
CC   -!- The product decarboxylates to 5-hydroxy-4-oxopentanoate.
CC   -!- The enzyme can decarboxylate 2-oxoglutarate.
CC   -!- Acetaldehyde can replace glyoxylate.
CC   -!- Formerly EC 4.1.3.15.
//
ID   2.2.1.6
DE   Acetolactate synthase.
AN   Acetohydroxy acid synthetase.
AN   Acetohydroxyacid synthase.
AN   Acetolactate pyruvate-lyase (carboxylating).
AN   Acetolactic synthetase.
AN   Alpha-acetohydroxy acid synthetase.
AN   Alpha-acetohydroxyacid synthase.
AN   Alpha-acetolactate synthase.
AN   Alpha-acetolactate synthetase.
CA   2 pyruvate = 2-acetolactate + CO(2).
CF   Thiamine diphosphate.
CC   -!- The reaction shown is in the pathway of biosynthesis of valine.
CC   -!- The enzyme can also transfer the acetaldehyde from pyruvate to
CC       2-oxobutanoate, forming 2-ethyl-2-hydroxy-3-oxobutanoate, also known
CC       as 2-aceto-2-hydroxybutanoate, a reaction in the biosynthesis of
CC       isoleucine.
CC   -!- Formerly EC 4.1.3.18.
PR   PROSITE; PDOC00166;
DR   P27818, ILVB1_BRANA;  Q41768, ILVB1_MAIZE;  P0A622, ILVB1_MYCTU;
DR   Q6K2E8, ILVB1_ORYSJ;  P09342, ILVB1_TOBAC;  P14874, ILVB2_BRANA;
DR   Q41769, ILVB2_MAIZE;  O06335, ILVB2_MYCTU;  Q7XKQ8, ILVB2_ORYSJ;
DR   P09114, ILVB2_TOBAC;  P27819, ILVB3_BRANA;  P17597, ILVB_ARATH ;
DR   P37251, ILVB_BACSU ;  P42463, ILVB_CORGL ;  Q5KPJ5, ILVB_CRYNJ ;
DR   Q6SSJ3, ILVB_CRYNV ;  O19929, ILVB_CYACA ;  P08142, ILVB_ECOLI ;
DR   Q09129, ILVB_ENTAE ;  O78518, ILVB_GUITH ;  P27696, ILVB_KLEPN ;
DR   Q02137, ILVB_LACLA ;  O08353, ILVB_METAO ;  Q57725, ILVB_METJA ;
DR   Q59498, ILVB_MYCAV ;  P0A623, ILVB_MYCBO ;  O33112, ILVB_MYCLE ;
DR   P69683, ILVB_PORPU ;  P69684, ILVB_PORUM ;  Q1XDF6, ILVB_PORYE ;
DR   Q04524, ILVB_RAOTE ;  P36620, ILVB_SCHPO ;  P27868, ILVB_SPIPL ;
DR   Q7U5G1, ILVB_SYNPX ;  P07342, ILVB_YEAST ;  P00892, ILVG_ECOLI ;
DR   P66947, ILVG_MYCBO ;  P66946, ILVG_MYCTU ;  O67703, ILVH_AQUAE ;
DR   O28555, ILVH_ARCFU ;  P37252, ILVH_BACSU ;  P57320, ILVH_BUCAI ;
DR   O85294, ILVH_BUCAP ;  Q89AP8, ILVH_BUCBP ;  Q9TLY1, ILVH_CYACA ;
DR   P00894, ILVH_ECOLI ;  Q9MS98, ILVH_GALSU ;  O78451, ILVH_GUITH ;
DR   P45260, ILVH_HAEIN ;  Q02140, ILVH_LACLA ;  Q57625, ILVH_METJA ;
DR   O27492, ILVH_METTH ;  Q59499, ILVH_MYCAV ;  P65162, ILVH_MYCBO ;
DR   O33113, ILVH_MYCLE ;  A0QUX7, ILVH_MYCS2 ;  P65161, ILVH_MYCTU ;
DR   P51230, ILVH_PORPU ;  Q1XDQ7, ILVH_PORYE ;  P21622, ILVH_SALTY ;
DR   Q55141, ILVH_SYNY3 ;  P57321, ILVI_BUCAI ;  O85293, ILVI_BUCAP ;
DR   Q89AP7, ILVI_BUCBP ;  Q9RQ65, ILVI_BUCSC ;  P00893, ILVI_ECOLI ;
DR   P45261, ILVI_HAEIN ;  P40811, ILVI_SALTY ;  P0ADG2, ILVM_ECOL6 ;
DR   P0ADG1, ILVM_ECOLI ;  P0ADG3, ILVM_SHIFL ;  P0ADG0, ILVN_ECO57 ;
DR   P0ADF9, ILVN_ECOL6 ;  P0ADF8, ILVN_ECOLI ;  Q04789, ILVX_BACSU ;
DR   O53554, ILVX_MYCTU ;
//
ID   2.2.1.7
DE   1-deoxy-D-xylulose-5-phosphate synthase.
AN   1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating).
AN   1-deoxyxylulose-5-phosphate synthase.
AN   DXP-synthase.
CA   Pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate
CA   + CO(2).
CF   Thiamine diphosphate.
CC   -!- The enzyme forms part of an alternative nonmevalonate pathway for
CC       terpenoid biosynthesis.
CC   -!- Formerly EC 4.1.3.37.
PR   PROSITE; PDOC00635;
DR   Q39UB1, DXS1_GEOMG ;  Q74FC3, DXS1_GEOSL ;  Q28WA7, DXS1_JANSC ;
DR   Q9F1V2, DXS1_KITGR ;  Q2RYD6, DXS1_RHORT ;  Q3J1A8, DXS1_RHOS4 ;
DR   Q16DV7, DXS1_ROSDO ;  Q82ML4, DXS1_STRAW ;  Q9X7W3, DXS1_STRCO ;
DR   Q5NN52, DXS1_ZYMMO ;  Q39RT4, DXS2_GEOMG ;  Q74CB0, DXS2_GEOSL ;
DR   Q28W25, DXS2_JANSC ;  Q8VUR8, DXS2_KITGR ;  Q2RR29, DXS2_RHORT ;
DR   Q3IYR6, DXS2_RHOS4 ;  Q16CP0, DXS2_ROSDO ;  Q82KW8, DXS2_STRAW ;
DR   Q8CJP7, DXS2_STRCO ;  Q5NM38, DXS2_ZYMMO ;  B0C8J3, DXS_ACAM1  ;
DR   A1TNR1, DXS_ACIAC  ;  Q6F7N5, DXS_ACIAD  ;  B0VQB8, DXS_ACIBS  ;
DR   B0V710, DXS_ACIBY  ;  C1F3C4, DXS_ACIC5  ;  B9MEU8, DXS_ACIET  ;
DR   A1W4U9, DXS_ACISJ  ;  A3MYS9, DXS_ACTP2  ;  B3H050, DXS_ACTP7  ;
DR   B0BSL0, DXS_ACTPJ  ;  A0KNF9, DXS_AERHH  ;  A4SJP9, DXS_AERS4  ;
DR   B9JAL7, DXS_AGRRK  ;  Q8UHD7, DXS_AGRT5  ;  B9JSL2, DXS_AGRVS  ;
DR   Q0VMI4, DXS_ALCBS  ;  Q0A8V7, DXS_ALHEH  ;  B6EIA7, DXS_ALISL  ;
DR   A8MFI7, DXS_ALKOO  ;  B4RVY8, DXS_ALTMD  ;  B8JFY1, DXS_ANAD2  ;
DR   Q2IPZ2, DXS_ANADE  ;  A7H9E8, DXS_ANADF  ;  B4UHF5, DXS_ANASK  ;
DR   Q3M4F6, DXS_ANAVT  ;  O67036, DXS_AQUAE  ;  Q38854, DXS_ARATH  ;
DR   A8EWN0, DXS_ARCB4  ;  Q5P228, DXS_AROAE  ;  A1R5N7, DXS_ARTAT  ;
DR   B8HH36, DXS_ARTCA  ;  A0JVG9, DXS_ARTS2  ;  A8IBS1, DXS_AZOC5  ;
DR   B6YRV5, DXS_AZOPC  ;  A1K4R0, DXS_AZOSB  ;  A7Z6J5, DXS_BACA2  ;
DR   C3P7V6, DXS_BACAA  ;  C3LJV1, DXS_BACAC  ;  Q81M54, DXS_BACAN  ;
DR   B7JM28, DXS_BACC0  ;  Q731B7, DXS_BACC1  ;  B7IXG8, DXS_BACC2  ;
DR   B7HB48, DXS_BACC4  ;  B7HNU0, DXS_BACC7  ;  A7GSJ5, DXS_BACCN  ;
DR   Q818R9, DXS_BACCR  ;  Q635A7, DXS_BACCZ  ;  Q5LH44, DXS_BACFN  ;
DR   Q64Y02, DXS_BACFR  ;  Q9K971, DXS_BACHD  ;  Q6HDY8, DXS_BACHK  ;
DR   Q65HJ2, DXS_BACLD  ;  A8FF11, DXS_BACP2  ;  Q5WF63, DXS_BACSK  ;
DR   P54523, DXS_BACSU  ;  Q8A0C2, DXS_BACTN  ;  A6L175, DXS_BACV8  ;
DR   A9VGD1, DXS_BACWK  ;  A1URW6, DXS_BARBK  ;  Q6G4D1, DXS_BARHE  ;
DR   Q6G0D4, DXS_BARQU  ;  A9IQP2, DXS_BART1  ;  Q1LTI9, DXS_BAUCH  ;
DR   B2IDK3, DXS_BEII9  ;  Q7VRH9, DXS_BLOFL  ;  Q493G7, DXS_BLOPB  ;
DR   Q2KZ15, DXS_BORA1  ;  Q7WL37, DXS_BORBR  ;  Q7W7Q0, DXS_BORPA  ;
DR   A9ITB0, DXS_BORPD  ;  Q7VV87, DXS_BORPE  ;  Q89RW1, DXS_BRAJA  ;
DR   A5EEQ0, DXS_BRASB  ;  A4YQ36, DXS_BRASO  ;  C0ZC10, DXS_BREBN  ;
DR   B2S9T6, DXS_BRUA1  ;  Q2YMF0, DXS_BRUA2  ;  Q57ET1, DXS_BRUAB  ;
DR   A9M8W0, DXS_BRUC2  ;  C0RHE3, DXS_BRUMB  ;  Q8YFM2, DXS_BRUME  ;
DR   A5VP09, DXS_BRUO2  ;  B0CKC0, DXS_BRUSI  ;  Q8G292, DXS_BRUSU  ;
DR   B8D9P1, DXS_BUCA5  ;  P57536, DXS_BUCAI  ;  Q8K9A1, DXS_BUCAP  ;
DR   B8D7Z3, DXS_BUCAT  ;  B1Z1G2, DXS_BURA4  ;  Q1BLY7, DXS_BURCA  ;
DR   B1K3S9, DXS_BURCC  ;  A0AYZ0, DXS_BURCH  ;  B4EN29, DXS_BURCJ  ;
DR   Q0BAL8, DXS_BURCM  ;  Q62DU1, DXS_BURMA  ;  A3P7W4, DXS_BURP0  ;
DR   Q3JKA3, DXS_BURP1  ;  A3NMF6, DXS_BURP6  ;  B2JP68, DXS_BURP8  ;
DR   Q63JF4, DXS_BURPS  ;  Q393P4, DXS_BURS3  ;  Q2T7N5, DXS_BURTA  ;
DR   Q13RX1, DXS_BURXL  ;  A0RMN5, DXS_CAMFF  ;  A7I2V7, DXS_CAMHC  ;
DR   A8FKB0, DXS_CAMJ8  ;  A7H552, DXS_CAMJD  ;  Q9PIH8, DXS_CAMJE  ;
DR   A1VY40, DXS_CAMJJ  ;  Q5HWF0, DXS_CAMJR  ;  O78328, DXS_CAPAN  ;
DR   Q3AAN0, DXS_CARHZ  ;  B8GXC4, DXS_CAUCN  ;  Q9A6M5, DXS_CAUCR  ;
DR   B0T3X7, DXS_CAUSK  ;  B3PF22, DXS_CELJU  ;  Q5L6H4, DXS_CHLAB  ;
DR   Q823V1, DXS_CHLCV  ;  Q253R7, DXS_CHLFF  ;  Q9PK62, DXS_CHLMU  ;
DR   Q9Z6J9, DXS_CHLPN  ;  B0B7P9, DXS_CHLT2  ;  Q3KM28, DXS_CHLTA  ;
DR   B0BBW4, DXS_CHLTB  ;  Q8KFI9, DXS_CHLTE  ;  O84335, DXS_CHLTR  ;
DR   Q1R1E5, DXS_CHRSD  ;  Q7NUK5, DXS_CHRVO  ;  A8AK34, DXS_CITK8  ;
DR   B0RC26, DXS_CLAMS  ;  Q97HD5, DXS_CLOAB  ;  A6LU48, DXS_CLOB8  ;
DR   B2V4R3, DXS_CLOBA  ;  B2TRM5, DXS_CLOBB  ;  Q18B68, DXS_CLOD6  ;
DR   B9E104, DXS_CLOK1  ;  A5N7J2, DXS_CLOK5  ;  A0Q0A4, DXS_CLONN  ;
DR   Q0TPD8, DXS_CLOP1  ;  Q8XJE1, DXS_CLOPE  ;  A9KMB8, DXS_CLOPH  ;
DR   Q0SS05, DXS_CLOPS  ;  Q894H0, DXS_CLOTE  ;  Q487D3, DXS_COLP3  ;
DR   Q6NGV3, DXS_CORDI  ;  Q8FPI2, DXS_COREF  ;  A4QEQ9, DXS_CORGB  ;
DR   Q8NPB2, DXS_CORGL  ;  Q4JVB5, DXS_CORJK  ;  Q0K860, DXS_CUPNH  ;
DR   Q474C2, DXS_CUPPJ  ;  B3R5H4, DXS_CUPTR  ;  B1WWM7, DXS_CYAA5  ;
DR   B8HWL8, DXS_CYAP4  ;  B7KAF7, DXS_CYAP7  ;  B7JVJ6, DXS_CYAP8  ;
DR   Q11NY7, DXS_CYTH3  ;  Q47BJ0, DXS_DECAR  ;  Q3Z8G9, DXS_DEHE1  ;
DR   A5FRB9, DXS_DEHSB  ;  Q3ZXC2, DXS_DEHSC  ;  Q1IZP0, DXS_DEIGD  ;
DR   Q9RUB5, DXS_DEIRA  ;  B1I3J6, DXS_DESAP  ;  Q30Z99, DXS_DESDG  ;
DR   B8FQ45, DXS_DESHD  ;  Q24V05, DXS_DESHY  ;  Q6AJQ1, DXS_DESPS  ;
DR   Q72CD3, DXS_DESVH  ;  A1VE69, DXS_DESVV  ;  B5YE06, DXS_DICT6  ;
DR   B8E247, DXS_DICTD  ;  A7ZIH3, DXS_ECO24  ;  B7UJP3, DXS_ECO27  ;
DR   B7MD78, DXS_ECO45  ;  B7L654, DXS_ECO55  ;  Q8XE76, DXS_ECO57  ;
DR   B5Z3S5, DXS_ECO5E  ;  B7NJ77, DXS_ECO7I  ;  B7MQD5, DXS_ECO81  ;
DR   B7M3Q9, DXS_ECO8A  ;  C4ZTH7, DXS_ECOBW  ;  B1XF08, DXS_ECODH  ;
DR   A7ZX72, DXS_ECOHS  ;  A1A890, DXS_ECOK1  ;  Q0TKM1, DXS_ECOL5  ;
DR   Q8FKB9, DXS_ECOL6  ;  B1J029, DXS_ECOLC  ;  P77488, DXS_ECOLI  ;
DR   B7N8X3, DXS_ECOLU  ;  B6HZM1, DXS_ECOSE  ;  B1LJH0, DXS_ECOSM  ;
DR   Q1RFC0, DXS_ECOUT  ;  C5BCH9, DXS_EDWI9  ;  A4W791, DXS_ENT38  ;
DR   A7MFG0, DXS_ENTS8  ;  Q6D844, DXS_ERWCT  ;  B2VHS3, DXS_ERWT9  ;
DR   Q2N6U5, DXS_ERYLH  ;  B7LMG7, DXS_ESCF3  ;  B1YLQ5, DXS_EXIS2  ;
DR   B0U0B3, DXS_FRAP2  ;  Q2JDD9, DXS_FRASC  ;  A8L0K9, DXS_FRASN  ;
DR   Q14HJ1, DXS_FRAT1  ;  A7NCA4, DXS_FRATF  ;  Q2A3D3, DXS_FRATH  ;
DR   B2SGK5, DXS_FRATM  ;  A0Q6B9, DXS_FRATN  ;  Q0BLU9, DXS_FRATO  ;
DR   Q5NG39, DXS_FRATT  ;  A4IXW5, DXS_FRATW  ;  Q8R639, DXS_FUSNN  ;
DR   Q75TB7, DXS_GEOKA  ;  C5D467, DXS_GEOSW  ;  A4IQR7, DXS_GEOTN  ;
DR   Q7NP63, DXS_GLOVI  ;  Q5FUB1, DXS_GLUOX  ;  Q7VNP7, DXS_HAEDU  ;
DR   Q4QKG6, DXS_HAEI8  ;  A5UC51, DXS_HAEIE  ;  A5UEV6, DXS_HAEIG  ;
DR   P45205, DXS_HAEIN  ;  B8F3A4, DXS_HAEPS  ;  Q0I3G1, DXS_HAES1  ;
DR   B0UUA4, DXS_HAES2  ;  Q2SA08, DXS_HAHCH  ;  B8D2I3, DXS_HALOH  ;
DR   C4K6M7, DXS_HAMD5  ;  Q7VIJ7, DXS_HELHP  ;  B0TEJ5, DXS_HELMI  ;
DR   B5ZAB7, DXS_HELPG  ;  Q1CUF6, DXS_HELPH  ;  Q9ZM94, DXS_HELPJ  ;
DR   O25121, DXS_HELPY  ;  Q0C154, DXS_HYPNA  ;  Q5QVE8, DXS_IDILO  ;
DR   B5Y0X1, DXS_KLEP3  ;  A6T5F3, DXS_KLEP7  ;  B2GJ56, DXS_KOCRD  ;
DR   C1DAW8, DXS_LARHH  ;  Q1MRB3, DXS_LAWIP  ;  Q6AFD5, DXS_LEIXX  ;
DR   Q04U59, DXS_LEPBJ  ;  Q053M2, DXS_LEPBL  ;  B1Y2X5, DXS_LEPCP  ;
DR   Q72U01, DXS_LEPIC  ;  Q8F153, DXS_LEPIN  ;  Q92BZ0, DXS_LISIN  ;
DR   C1L2S1, DXS_LISMC  ;  Q71ZV7, DXS_LISMF  ;  Q8Y7C1, DXS_LISMO  ;
DR   A0AIG6, DXS_LISW6  ;  B1HRX4, DXS_LYSSC  ;  B9E6Q6, DXS_MACCJ  ;
DR   Q2W367, DXS_MAGSA  ;  A0L6H3, DXS_MAGSM  ;  Q65TP4, DXS_MANSM  ;
DR   Q0ARE5, DXS_MARMM  ;  A6VUE5, DXS_MARMS  ;  Q11KE0, DXS_MESSB  ;
DR   Q60AN1, DXS_METCA  ;  Q1GZD7, DXS_METFK  ;  B3DW88, DXS_METI4  ;
DR   A2SJ46, DXS_METPP  ;  B0JL88, DXS_MICAN  ;  Q2RIB9, DXS_MOOTA  ;
DR   A0QIL6, DXS_MYCA1  ;  B1MCU7, DXS_MYCA9  ;  P0A555, DXS_MYCBO  ;
DR   A1KM20, DXS_MYCBP  ;  C1AFE1, DXS_MYCBT  ;  A4TCS5, DXS_MYCGI  ;
DR   B8ZQW9, DXS_MYCLB  ;  Q50000, DXS_MYCLE  ;  Q73W57, DXS_MYCPA  ;
DR   Q8EWX7, DXS_MYCPE  ;  A0QW19, DXS_MYCS2  ;  A3PYK6, DXS_MYCSJ  ;
DR   A1UF44, DXS_MYCSK  ;  Q1B9W8, DXS_MYCSS  ;  A5U634, DXS_MYCTA  ;
DR   P0A554, DXS_MYCTU  ;  A0PT40, DXS_MYCUA  ;  A1T7Z0, DXS_MYCVP  ;
DR   Q1D3G4, DXS_MYXXD  ;  B2A526, DXS_NATTJ  ;  Q5FAI2, DXS_NEIG1  ;
DR   B4RNW6, DXS_NEIG2  ;  A9M1G3, DXS_NEIM0  ;  Q9JW13, DXS_NEIMA  ;
DR   Q9JXV7, DXS_NEIMB  ;  A1KS32, DXS_NEIMF  ;  Q0AFY6, DXS_NITEC  ;
DR   Q82VD3, DXS_NITEU  ;  Q1QQ40, DXS_NITHX  ;  Q2YCH7, DXS_NITMU  ;
DR   Q3JAD1, DXS_NITOC  ;  A6Q1Z6, DXS_NITSB  ;  Q3SUZ1, DXS_NITWN  ;
DR   Q5YTA2, DXS_NOCFA  ;  A1SKM6, DXS_NOCSJ  ;  B2J5P1, DXS_NOSP7  ;
DR   Q8YZ80, DXS_NOSS1  ;  Q2GC13, DXS_NOVAD  ;  A6WWC4, DXS_OCHA4  ;
DR   O22567, DXS_ORYSJ  ;  A6LFB9, DXS_PARD8  ;  Q6MDK6, DXS_PARUW  ;
DR   P57848, DXS_PASMU  ;  C6DB37, DXS_PECCP  ;  Q3A3Z6, DXS_PELCD  ;
DR   Q3B5P3, DXS_PELLD  ;  A5D2Z6, DXS_PELTS  ;  Q4FN07, DXS_PELUB  ;
DR   B4RGW0, DXS_PHEZH  ;  Q7N0J7, DXS_PHOLL  ;  Q6LU07, DXS_PHOPR  ;
DR   A1VMD7, DXS_POLNA  ;  Q12CQ9, DXS_POLSJ  ;  B2RMK4, DXS_PORG3  ;
DR   Q7MSZ3, DXS_PORGI  ;  Q6A8V3, DXS_PROAC  ;  A3PCV0, DXS_PROM0  ;
DR   A2C220, DXS_PROM1  ;  A8G4R9, DXS_PROM2  ;  A2C9X1, DXS_PROM3  ;
DR   A9BAC1, DXS_PROM4  ;  A2BWN6, DXS_PROM5  ;  Q31AZ2, DXS_PROM9  ;
DR   Q7VC14, DXS_PROMA  ;  B4EU31, DXS_PROMH  ;  Q7V7Q3, DXS_PROMM  ;
DR   Q7V1G6, DXS_PROMP  ;  A2BR27, DXS_PROMS  ;  Q46L36, DXS_PROMT  ;
DR   A4SDG1, DXS_PROVI  ;  Q48NX0, DXS_PSE14  ;  Q15W93, DXS_PSEA6  ;
DR   A6V058, DXS_PSEA7  ;  B7V7R4, DXS_PSEA8  ;  Q02SL1, DXS_PSEAB  ;
DR   Q9KGU7, DXS_PSEAE  ;  Q1IFL1, DXS_PSEE4  ;  Q4K5A5, DXS_PSEF5  ;
DR   C3K2R1, DXS_PSEFS  ;  Q3II09, DXS_PSEHT  ;  A4XZ25, DXS_PSEMY  ;
DR   A5VXW9, DXS_PSEP1  ;  Q3K660, DXS_PSEPF  ;  B0KL79, DXS_PSEPG  ;
DR   Q88QG7, DXS_PSEPK  ;  B1J3G4, DXS_PSEPW  ;  Q889Q1, DXS_PSESM  ;
DR   Q4ZYU8, DXS_PSEU2  ;  A4VQS8, DXS_PSEU5  ;  Q4FV64, DXS_PSYA2  ;
DR   Q1QE74, DXS_PSYCK  ;  A1SWW6, DXS_PSYIN  ;  Q1LK34, DXS_RALME  ;
DR   B2U930, DXS_RALPJ  ;  Q8XX95, DXS_RALSO  ;  A9WRA9, DXS_RENSM  ;
DR   B3PS68, DXS_RHIE6  ;  Q2KBR2, DXS_RHIEC  ;  Q1MKN4, DXS_RHIL3  ;
DR   Q985Y3, DXS_RHILO  ;  B5ZS68, DXS_RHILW  ;  Q92RJ1, DXS_RHIME  ;
DR   Q7UWB7, DXS_RHOBA  ;  P26242, DXS_RHOCA  ;  B6IRB5, DXS_RHOCS  ;
DR   C0ZYV9, DXS_RHOE4  ;  Q21UG7, DXS_RHOFD  ;  Q2IRL7, DXS_RHOP2  ;
DR   Q07SR3, DXS_RHOP5  ;  Q6NB76, DXS_RHOPA  ;  Q21A74, DXS_RHOPB  ;
DR   Q130G7, DXS_RHOPS  ;  B3QFY7, DXS_RHOPT  ;  Q0S1H1, DXS_RHOSR  ;
DR   Q21F93, DXS_SACD2  ;  A4FAQ5, DXS_SACEN  ;  B5EXG3, DXS_SALA4  ;
DR   A9MM42, DXS_SALAR  ;  Q57SE2, DXS_SALCH  ;  B5FKS7, DXS_SALDC  ;
DR   B5QTH0, DXS_SALEP  ;  B5R6S3, DXS_SALG2  ;  B4T8R3, DXS_SALHS  ;
DR   B4SWR4, DXS_SALNS  ;  Q5PFR6, DXS_SALPA  ;  A9MX09, DXS_SALPB  ;
DR   C0Q7U7, DXS_SALPC  ;  B5BDB0, DXS_SALPK  ;  B4TMA2, DXS_SALSV  ;
DR   Q8Z8X3, DXS_SALTI  ;  Q8ZRD1, DXS_SALTY  ;  A8GAP2, DXS_SERP5  ;
DR   A1S8D4, DXS_SHEAM  ;  B8EAU7, DXS_SHEB2  ;  A3D2B2, DXS_SHEB5  ;
DR   A6WL04, DXS_SHEB8  ;  A9KTL5, DXS_SHEB9  ;  Q12L26, DXS_SHEDO  ;
DR   Q07ZD4, DXS_SHEFN  ;  B0TQ36, DXS_SHEHH  ;  A3QGN9, DXS_SHELP  ;
DR   Q8EGR9, DXS_SHEON  ;  A8H6X1, DXS_SHEPA  ;  A4Y4X0, DXS_SHEPC  ;
DR   B8CS19, DXS_SHEPW  ;  A0KZA9, DXS_SHESA  ;  A8FYL0, DXS_SHESH  ;
DR   Q0HGL5, DXS_SHESM  ;  Q0HSW6, DXS_SHESR  ;  A1RLV3, DXS_SHESW  ;
DR   B1KQY8, DXS_SHEWM  ;  B2U4M3, DXS_SHIB3  ;  Q325I1, DXS_SHIBS  ;
DR   Q32JH8, DXS_SHIDS  ;  Q83SG2, DXS_SHIFL  ;  Q3Z4Y9, DXS_SHISS  ;
DR   Q5LX42, DXS_SILPO  ;  Q1GCG4, DXS_SILST  ;  Q2NV94, DXS_SODGM  ;
DR   Q1GQK9, DXS_SPHAL  ;  A5V6A9, DXS_SPHWW  ;  Q9RBN6, DXS_STRC1  ;
DR   B1VWJ8, DXS_STRGG  ;  B2FN57, DXS_STRMK  ;  Q30TC5, DXS_SULDN  ;
DR   Q67NB6, DXS_SYMTH  ;  Q2LUA7, DXS_SYNAS  ;  Q8GAA0, DXS_SYNE7  ;
DR   Q2JTX2, DXS_SYNJA  ;  Q2JK64, DXS_SYNJB  ;  B1XKC5, DXS_SYNP2  ;
DR   Q9R6S7, DXS_SYNP6  ;  A5GL34, DXS_SYNPW  ;  Q7U6P6, DXS_SYNPX  ;
DR   A5GTT4, DXS_SYNR3  ;  Q0IAA6, DXS_SYNS3  ;  Q3AXZ4, DXS_SYNS9  ;
DR   Q3AJP8, DXS_SYNSC  ;  Q0AZE2, DXS_SYNWW  ;  P73067, DXS_SYNY3  ;
DR   Q8DL74, DXS_THEEB  ;  Q47NL9, DXS_THEFY  ;  Q9X291, DXS_THEMA  ;
DR   A5ILK2, DXS_THEP1  ;  B9L1L6, DXS_THERP  ;  B1LAQ3, DXS_THESQ  ;
DR   Q72H81, DXS_THET2  ;  Q5SMD7, DXS_THET8  ;  Q8RAC5, DXS_THETN  ;
DR   Q3SKF1, DXS_THIDA  ;  B8GN62, DXS_THISH  ;  Q73LF4, DXS_TREDE  ;
DR   O83796, DXS_TREPA  ;  B2S462, DXS_TREPS  ;  Q10ZY2, DXS_TRIEI  ;
DR   Q83I20, DXS_TROW8  ;  Q83G46, DXS_TROWT  ;  A1WN06, DXS_VEREI  ;
DR   A5F331, DXS_VIBC3  ;  Q9KTL3, DXS_VIBCH  ;  C3LTD9, DXS_VIBCM  ;
DR   Q5E6Z0, DXS_VIBF1  ;  B5FBG6, DXS_VIBFM  ;  A7MYC6, DXS_VIBHB  ;
DR   Q87RU0, DXS_VIBPA  ;  B7VJA1, DXS_VIBSL  ;  Q8DFA3, DXS_VIBVU  ;
DR   Q7MN49, DXS_VIBVY  ;  Q8D357, DXS_WIGBR  ;  Q7M7Z0, DXS_WOLSU  ;
DR   Q8PJG7, DXS_XANAC  ;  Q3BRW8, DXS_XANC5  ;  Q4UW29, DXS_XANC8  ;
DR   Q8P815, DXS_XANCP  ;  Q2P472, DXS_XANOM  ;  B2SQV8, DXS_XANOP  ;
DR   Q5H1A0, DXS_XANOR  ;  A7IPK6, DXS_XANP2  ;  B2I607, DXS_XYLF2  ;
DR   Q9PB95, DXS_XYLFA  ;  B0U3E1, DXS_XYLFM  ;  Q87C03, DXS_XYLFT  ;
DR   A1JNR7, DXS_YERE8  ;  A7FLE4, DXS_YERP3  ;  Q1C4I9, DXS_YERPA  ;
DR   B2K6T7, DXS_YERPB  ;  Q8ZC45, DXS_YERPE  ;  A9QZS3, DXS_YERPG  ;
DR   Q1CL87, DXS_YERPN  ;  A4TPG2, DXS_YERPP  ;  Q66DV4, DXS_YERPS  ;
DR   B1JID8, DXS_YERPY  ;
//
ID   2.2.1.8
DE   Fluorothreonine transaldolase.
CA   L-threonine + fluoroacetaldehyde = acetaldehyde + 4-fluoro-L-threonine.
CF   Pyridoxal 5'-phosphate.
CC   -!- Can also convert chloroacetaldehyde into 4-chloro-L-threonine.
CC   -!- Unlike EC 2.1.2.1 does not use glycine as a substrate.
//
ID   2.2.1.9
DE   2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid
DE   synthase.
AN   SEPHCHC synthase.
CA   Isochorismate + 2-oxoglutarate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-
CA   cyclohex-3-ene-1-carboxylate + CO(2).
CF   Magnesium.
CC   -!- Involved in the biosynthesis of vitamin K(2) (menaquinone).
CC   -!- In most anaerobes and all Gram-positive aerobes, menaquinone is the
CC       sole electron transporter in the respiratory chain and is essential
CC       for their survival.
CC   -!- It had previously been thought that the products of the reaction were
CC       (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate
CC       (SHCHC), pyruvate and CO(2) but it is now known that two separate
CC       enzymes are involved: this enzyme and EC 4.2.99.20.
CC   -!- Under basic conditions, the product can spontaneously lose pyruvate
CC       to form SHCHC.
CC   -!- Formerly EC 2.5.1.64 and EC 2.5.1.n1.
DR   B0C1Y1, MEND_ACAM1 ;  A3N348, MEND_ACTP2 ;  B3GZ01, MEND_ACTP7 ;
DR   B0BSH8, MEND_ACTPJ ;  A6VMF8, MEND_ACTSZ ;  A0KFN8, MEND_AERHH ;
DR   A4SS26, MEND_AERS4 ;  B2UPN5, MEND_AKKM8 ;  Q3M3Y3, MEND_ANAVT ;
DR   A1R996, MEND_ARTAT ;  A0JZP6, MEND_ARTS2 ;  A7Z812, MEND_BACA2 ;
DR   A0RK76, MEND_BACAH ;  Q81K94, MEND_BACAN ;  Q72YK6, MEND_BACC1 ;
DR   A7GU91, MEND_BACCN ;  Q816H7, MEND_BACCR ;  Q632I2, MEND_BACCZ ;
DR   Q5LFS5, MEND_BACFN ;  Q64WR0, MEND_BACFR ;  Q6HC26, MEND_BACHK ;
DR   Q65FT2, MEND_BACLD ;  A8FGK9, MEND_BACP2 ;  P23970, MEND_BACSU ;
DR   Q89YN0, MEND_BACTN ;  A6L313, MEND_BACV8 ;  A9VM77, MEND_BACWK ;
DR   Q6MHQ6, MEND_BDEBA ;  A9WB45, MEND_CHLAA ;  Q3APX4, MEND_CHLCH ;
DR   B3EG68, MEND_CHLL2 ;  B3QL00, MEND_CHLP8 ;  B3EMZ5, MEND_CHLPB ;
DR   A1BI74, MEND_CHLPD ;  Q8KBE8, MEND_CHLTE ;  A8ADW9, MEND_CITK8 ;
DR   A5CUV9, MEND_CLAM3 ;  B0RCZ5, MEND_CLAMS ;  Q6NJH8, MEND_CORDI ;
DR   Q8FSB6, MEND_COREF ;  A4QBE1, MEND_CORGB ;  Q4JT09, MEND_CORJK ;
DR   B1WZR3, MEND_CYAA5 ;  B7K8M6, MEND_CYAP7 ;  B7K0T5, MEND_CYAP8 ;
DR   Q11U88, MEND_CYTH3 ;  Q47DK0, MEND_DECAR ;  B8FTY8, MEND_DESHD ;
DR   Q250I5, MEND_DESHY ;  Q6ARP3, MEND_DESPS ;  A7ZP83, MEND_ECO24 ;
DR   B7UFS7, MEND_ECO27 ;  B7MG32, MEND_ECO45 ;  B7LAT0, MEND_ECO55 ;
DR   Q8XDX8, MEND_ECO57 ;  B5YXQ8, MEND_ECO5E ;  B7NNU4, MEND_ECO7I ;
DR   B7MXE7, MEND_ECO81 ;  B7M5U7, MEND_ECO8A ;  C4ZUA7, MEND_ECOBW ;
DR   B1X8X8, MEND_ECODH ;  A8A2D2, MEND_ECOHS ;  A1ADB6, MEND_ECOK1 ;
DR   Q0TFH7, MEND_ECOL5 ;  Q8FFL1, MEND_ECOL6 ;  B1IXS2, MEND_ECOLC ;
DR   P17109, MEND_ECOLI ;  B7N5N0, MEND_ECOLU ;  B6I7K8, MEND_ECOSE ;
DR   B1LLL9, MEND_ECOSM ;  Q1R9E9, MEND_ECOUT ;  C5B7I2, MEND_EDWI9 ;
DR   A4WCP9, MEND_ENT38 ;  Q838J9, MEND_ENTFA ;  A7MHU4, MEND_ENTS8 ;
DR   Q6D7W4, MEND_ERWCT ;  B7LM66, MEND_ESCF3 ;  A5FG67, MEND_FLAJ1 ;
DR   A6H070, MEND_FLAPJ ;  Q5KVX6, MEND_GEOKA ;  A4IS14, MEND_GEOTN ;
DR   A0M345, MEND_GRAFK ;  Q7VKM9, MEND_HAEDU ;  Q4QNQ7, MEND_HAEI8 ;
DR   A5UAK7, MEND_HAEIE ;  A5UGA0, MEND_HAEIG ;  P44612, MEND_HAEIN ;
DR   Q0I316, MEND_HAES1 ;  B0UT51, MEND_HAES2 ;  A1WW41, MEND_HALHL ;
DR   B9LNE4, MEND_HALLT ;  Q5V3T2, MEND_HALMA ;  B0R4U1, MEND_HALS3 ;
DR   Q9HQN3, MEND_HALSA ;  Q18J11, MEND_HALWD ;  A6W5P6, MEND_KINRD ;
DR   B5XNX0, MEND_KLEP3 ;  A6TBV8, MEND_KLEP7 ;  Q9CHK0, MEND_LACLA ;
DR   A2RM73, MEND_LACLM ;  Q030P1, MEND_LACLS ;  Q6AHC2, MEND_LEIXX ;
DR   B1MZ27, MEND_LEUCK ;  Q03Y61, MEND_LEUMM ;  Q92AY5, MEND_LISIN ;
DR   Q71YZ2, MEND_LISMF ;  Q8Y6K9, MEND_LISMO ;  A0AJC9, MEND_LISW6 ;
DR   B1HY21, MEND_LYSSC ;  Q65RK9, MEND_MANSM ;  B0JII8, MEND_MICAN ;
DR   A0QLC9, MEND_MYCA1 ;  B1MHC6, MEND_MYCA9 ;  Q7U1S4, MEND_MYCBO ;
DR   A1KG32, MEND_MYCBP ;  C1AKN5, MEND_MYCBT ;  A4T174, MEND_MYCGI ;
DR   B8ZSY2, MEND_MYCLB ;  Q9CBB0, MEND_MYCLE ;  B2HRP6, MEND_MYCMM ;
DR   Q73SM1, MEND_MYCPA ;  A0QRG5, MEND_MYCS2 ;  A3PUH9, MEND_MYCSJ ;
DR   A1UAX3, MEND_MYCSK ;  Q1BE13, MEND_MYCSS ;  A5TZT5, MEND_MYCTA ;
DR   A1QNY1, MEND_MYCTF ;  O06421, MEND_MYCTU ;  A0PLU9, MEND_MYCUA ;
DR   A1T3R3, MEND_MYCVP ;  Q1D6K1, MEND_MYXXD ;  Q3IQZ0, MEND_NATPD ;
DR   Q5YPA6, MEND_NOCFA ;  A1SE17, MEND_NOCSJ ;  Q8YZZ2, MEND_NOSS1 ;
DR   Q8CZD8, MEND_OCEIH ;  A6LB35, MEND_PARD8 ;  Q6MCA7, MEND_PARUW ;
DR   Q9CPI4, MEND_PASMU ;  C6DBP2, MEND_PECCP ;  Q3B612, MEND_PELLD ;
DR   B4SET5, MEND_PELPB ;  Q7N2K3, MEND_PHOLL ;  Q6LNX3, MEND_PHOPR ;
DR   Q7MUI9, MEND_PORGI ;  B4S4J4, MEND_PROA2 ;  Q6A9B0, MEND_PROAC ;
DR   A3PBY1, MEND_PROM0 ;  A2C165, MEND_PROM1 ;  A8G3X3, MEND_PROM2 ;
DR   A2CAW2, MEND_PROM3 ;  A2BVS0, MEND_PROM5 ;  Q31BS7, MEND_PROM9 ;
DR   Q7VBN8, MEND_PROMA ;  B4EZ42, MEND_PROMH ;  Q7V8E7, MEND_PROMM ;
DR   Q7V277, MEND_PROMP ;  A2BQ88, MEND_PROMS ;  Q46LU3, MEND_PROMT ;
DR   A4SD60, MEND_PROVI ;  A1SRV2, MEND_PSYIN ;  A9WRT6, MEND_RENSM ;
DR   C0ZV17, MEND_RHOE4 ;  C1AYZ0, MEND_RHOOB ;  Q0SF82, MEND_RHOSR ;
DR   A7NRP8, MEND_ROSCS ;  A5UPB5, MEND_ROSS1 ;  Q1AS21, MEND_RUBXD ;
DR   A4FPV1, MEND_SACEN ;  B5EZI8, MEND_SALA4 ;  A9MJB6, MEND_SALAR ;
DR   Q57M47, MEND_SALCH ;  B5FPE8, MEND_SALDC ;  B5R2Z0, MEND_SALEP ;
DR   B5RCD4, MEND_SALG2 ;  B4TBH6, MEND_SALHS ;  B4SYY1, MEND_SALNS ;
DR   Q5PN76, MEND_SALPA ;  A9N5A2, MEND_SALPB ;  C0Q059, MEND_SALPC ;
DR   B5BCN6, MEND_SALPK ;  Q2S2V6, MEND_SALRD ;  B4TPJ2, MEND_SALSV ;
DR   Q8Z533, MEND_SALTI ;  Q8ZNE8, MEND_SALTY ;  A8GGZ1, MEND_SERP5 ;
DR   A1SBA6, MEND_SHEAM ;  A3CYZ9, MEND_SHEB5 ;  A6WTY4, MEND_SHEB8 ;
DR   A9KU65, MEND_SHEB9 ;  Q089C0, MEND_SHEFN ;  B0TNX0, MEND_SHEHH ;
DR   A3QJ17, MEND_SHELP ;  Q8E8T4, MEND_SHEON ;  A8H9P4, MEND_SHEPA ;
DR   A4Y259, MEND_SHEPC ;  A0L2B4, MEND_SHESA ;  A8FPR6, MEND_SHESH ;
DR   Q0HDN7, MEND_SHESM ;  Q0HPY8, MEND_SHESR ;  A1RPV7, MEND_SHESW ;
DR   B1KM97, MEND_SHEWM ;  B2TW50, MEND_SHIB3 ;  Q31YJ3, MEND_SHIBS ;
DR   Q32DS4, MEND_SHIDS ;  Q0T2L9, MEND_SHIF8 ;  Q821B0, MEND_SHIFL ;
DR   Q3YZU2, MEND_SHISS ;  A9GFL5, MEND_SORC5 ;  A7X0S7, MEND_STAA1 ;
DR   A6U0L1, MEND_STAA2 ;  Q2FI34, MEND_STAA3 ;  Q2FZL7, MEND_STAA8 ;
DR   A5IRS9, MEND_STAA9 ;  Q2YX30, MEND_STAAB ;  Q5HH40, MEND_STAAC ;
DR   A6QFQ3, MEND_STAAE ;  Q99V50, MEND_STAAM ;  Q7A6B1, MEND_STAAN ;
DR   Q6GI39, MEND_STAAR ;  Q6GAG9, MEND_STAAS ;  A8Z0D7, MEND_STAAT ;
DR   Q8NXA2, MEND_STAAW ;  Q5HQC5, MEND_STAEQ ;  Q8CPQ5, MEND_STAES ;
DR   Q4L547, MEND_STAHJ ;  Q49WG6, MEND_STAS1 ;  Q2LXE3, MEND_SYNAS ;
DR   Q31NA4, MEND_SYNE7 ;  Q2JY06, MEND_SYNJA ;  Q2JK10, MEND_SYNJB ;
DR   Q5N5V7, MEND_SYNP6 ;  A5GKI2, MEND_SYNPW ;  Q7U7I5, MEND_SYNPX ;
DR   A5GT34, MEND_SYNR3 ;  Q0I9Z1, MEND_SYNS3 ;  Q3AVF6, MEND_SYNS9 ;
DR   Q3AKK3, MEND_SYNSC ;  Q55725, MEND_SYNY3 ;  Q8DMI6, MEND_THEEB ;
DR   Q47Q20, MEND_THEFY ;  Q10XD8, MEND_TRIEI ;  A5F6T1, MEND_VIBC3 ;
DR   Q9KQM3, MEND_VIBCH ;  C3LNS6, MEND_VIBCM ;  Q5E480, MEND_VIBF1 ;
DR   A7MZS0, MEND_VIBHB ;  Q87R69, MEND_VIBPA ;  B7VHY7, MEND_VIBSL ;
DR   Q8D820, MEND_VIBVU ;  Q7MMF6, MEND_VIBVY ;  A1JKT8, MEND_YERE8 ;
DR   A7FGT2, MEND_YERP3 ;  Q1C6D7, MEND_YERPA ;  B2K7Z3, MEND_YERPB ;
DR   Q7CJ76, MEND_YERPE ;  A9R6J0, MEND_YERPG ;  Q1CHS9, MEND_YERPN ;
DR   A4TM08, MEND_YERPP ;  Q669C7, MEND_YERPS ;  B1JH88, MEND_YERPY ;
DR   Q15KI9, PHYLO_ARATH;
//
ID   2.3.1.1
DE   Amino-acid N-acetyltransferase.
AN   N-acetylglutamate synthase.
CA   Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate.
CC   -!- Also acts with L-aspartate and, more slowly, with some other amino
CC       acids.
DR   A3N062, ARGA_ACTP2 ;  B3GXD3, ARGA_ACTP7 ;  B0BNY0, ARGA_ACTPJ ;
DR   A6VMR4, ARGA_ACTSZ ;  A0KLC8, ARGA_AERHH ;  A4SNY1, ARGA_AERS4 ;
DR   C1DJG1, ARGA_AZOVD ;  O66143, ARGA_BUCAI ;  P59099, ARGA_BUCAP ;
DR   P0A6C7, ARGA_ECO57 ;  P0A6C6, ARGA_ECOL6 ;  P0A6C5, ARGA_ECOLI ;
DR   C5BH95, ARGA_EDWI9 ;  A4WDZ5, ARGA_ENT38 ;  Q6D8H5, ARGA_ERWCT ;
DR   B7LW98, ARGA_ESCF3 ;  Q7VLN8, ARGA_HAEDU ;  Q65UJ9, ARGA_MANSM ;
DR   Q9JW21, ARGA_NEIMA ;  Q9JXU9, ARGA_NEIMB ;  Q9CMJ6, ARGA_PASMU ;
DR   C6DAG1, ARGA_PECCP ;  Q7N8S4, ARGA_PHOLL ;  Q6LMZ6, ARGA_PHOPR ;
DR   B4F2F5, ARGA_PROMH ;  A6VDY0, ARGA_PSEA7 ;  B7V594, ARGA_PSEA8 ;
DR   Q02EG0, ARGA_PSEAB ;  P22567, ARGA_PSEAE ;  Q4K434, ARGA_PSEF5 ;
DR   C3K3V3, ARGA_PSEFS ;  A4XP61, ARGA_PSEMY ;  Q3K4Z8, ARGA_PSEPF ;
DR   B0KP70, ARGA_PSEPG ;  P0A0Z9, ARGA_PSEPK ;  P0A100, ARGA_PSEPU ;
DR   Q88AR2, ARGA_PSESM ;  P61919, ARGA_PSESY ;  Q4ZZU5, ARGA_PSEU2 ;
DR   Q8XZZ5, ARGA_RALSO ;  A9MS91, ARGA_SALAR ;  Q8Z421, ARGA_SALTI ;
DR   Q8ZMB8, ARGA_SALTY ;  A8GIG8, ARGA_SERP5 ;  P59292, ARGA_SHEON ;
DR   P59293, ARGA_SHIFL ;  Q9KPQ0, ARGA_VIBCH ;  Q5E7B6, ARGA_VIBF1 ;
DR   B5FAS8, ARGA_VIBFM ;  Q87M87, ARGA_VIBPA ;  B7VJZ6, ARGA_VIBSL ;
DR   P59294, ARGA_VIBVU ;  Q7MIA6, ARGA_VIBVY ;  A1JPB6, ARGA_YERE8 ;
DR   A7FFE9, ARGA_YERP3 ;  Q1CAR0, ARGA_YERPA ;  B2JZ56, ARGA_YERPB ;
DR   Q8ZH86, ARGA_YERPE ;  A9R2Q4, ARGA_YERPG ;  Q1CFC4, ARGA_YERPN ;
DR   Q667G9, ARGA_YERPS ;  B1JQD9, ARGA_YERPY ;  Q9K3D6, ARGHA_MORAB;
DR   Q9K3D7, ARGHA_MORPR;  A6S146, ARGJ1_BOTFB;  Q97GH6, ARGJ1_CLOAB;
DR   Q8YVA8, ARGJ1_NOSS1;  A7E5P6, ARGJ1_SCLS1;  A6S9T6, ARGJ2_BOTFB;
DR   Q97ET6, ARGJ2_CLOAB;  Q8YPF9, ARGJ2_NOSS1;  A7EDG9, ARGJ2_SCLS1;
DR   Q6FED8, ARGJ_ACIAD ;  Q8UA56, ARGJ_AGRT5 ;  C0NE02, ARGJ_AJECG ;
DR   C6HSY8, ARGJ_AJECH ;  A6R040, ARGJ_AJECN ;  C5GXZ4, ARGJ_AJEDR ;
DR   C5K110, ARGJ_AJEDS ;  O67100, ARGJ_AQUAE ;  Q9ZUR7, ARGJ_ARATH ;
DR   O29118, ARGJ_ARCFU ;  Q5P706, ARGJ_AROAE ;  C5FHS6, ARGJ_ARTOC ;
DR   Q759Y5, ARGJ_ASHGO ;  A1CAP4, ARGJ_ASPCL ;  B0Y3W4, ARGJ_ASPFC ;
DR   B8NEJ3, ARGJ_ASPFN ;  Q4WUE0, ARGJ_ASPFU ;  A2QGS5, ARGJ_ASPNC ;
DR   Q2U7R8, ARGJ_ASPOR ;  Q0CDB9, ARGJ_ASPTN ;  Q9ZJ14, ARGJ_BACAM ;
DR   Q81M96, ARGJ_BACAN ;  P62057, ARGJ_BACC1 ;  Q818W0, ARGJ_BACCR ;
DR   Q635F1, ARGJ_BACCZ ;  Q9K8V3, ARGJ_BACHD ;  Q6HE29, ARGJ_BACHK ;
DR   Q65LE9, ARGJ_BACLD ;  Q5WEW8, ARGJ_BACSK ;  P36843, ARGJ_BACSU ;
DR   Q6G5T6, ARGJ_BARHE ;  Q6G0Q6, ARGJ_BARQU ;  Q8G5F0, ARGJ_BIFLO ;
DR   Q7WF54, ARGJ_BORBR ;  Q7W3S6, ARGJ_BORPA ;  Q7VSW3, ARGJ_BORPE ;
DR   P59610, ARGJ_BRAJA ;  Q57AV8, ARGJ_BRUAB ;  Q8YJF9, ARGJ_BRUME ;
DR   Q8FYE2, ARGJ_BRUSU ;  Q62GT9, ARGJ_BURMA ;  Q3JNE9, ARGJ_BURP1 ;
DR   Q63QK7, ARGJ_BURPS ;  Q39JW0, ARGJ_BURS3 ;  Q5AH38, ARGJ_CANAL ;
DR   C4YTS0, ARGJ_CANAW ;  B9WK98, ARGJ_CANDC ;  Q6FU44, ARGJ_CANGA ;
DR   C5MG55, ARGJ_CANTT ;  Q3A9W1, ARGJ_CARHZ ;  Q9A3Y4, ARGJ_CAUCR ;
DR   Q2HAX7, ARGJ_CHAGB ;  Q3ASI6, ARGJ_CHLCH ;  P59611, ARGJ_CHLTE ;
DR   Q7P0T8, ARGJ_CHRVO ;  Q3C251, ARGJ_CITLA ;  C4Y584, ARGJ_CLAL4 ;
DR   C5P7K2, ARGJ_COCP7 ;  Q486G0, ARGJ_COLP3 ;  A8NAN2, ARGJ_COPC7 ;
DR   Q4JW03, ARGJ_CORJK ;  P0CM21, ARGJ_CRYNB ;  P0CM20, ARGJ_CRYNJ ;
DR   Q46X04, ARGJ_CUPPJ ;  Q6BKT4, ARGJ_DEBHA ;  Q47AB5, ARGJ_DECAR ;
DR   Q3Z731, ARGJ_DEHE1 ;  Q3ZYG4, ARGJ_DEHSC ;  Q9RTQ2, ARGJ_DEIRA ;
DR   Q6AJL0, ARGJ_DESPS ;  P62060, ARGJ_DESVH ;  Q54DY1, ARGJ_DICDI ;
DR   Q5AVF8, ARGJ_EMENI ;  Q5L1V4, ARGJ_GEOKA ;  Q07908, ARGJ_GEOSE ;
DR   P62061, ARGJ_GEOSL ;  Q7NE46, ARGJ_GLOVI ;  Q5FQD0, ARGJ_GLUOX ;
DR   Q93EJ3, ARGJ_HELHP ;  Q6CII9, ARGJ_KLULA ;  B0D316, ARGJ_LACBS ;
DR   Q9CHD4, ARGJ_LACLA ;  O08319, ARGJ_LACPL ;  C5DCN3, ARGJ_LACTC ;
DR   P62062, ARGJ_LEPIC ;  Q8EYV8, ARGJ_LEPIN ;  Q92BB8, ARGJ_LISIN ;
DR   Q71Z77, ARGJ_LISMF ;  Q8Y6U2, ARGJ_LISMO ;  A5E7B9, ARGJ_LODEL ;
DR   A4R5F6, ARGJ_MAGO7 ;  C0PF72, ARGJ_MAIZE ;  A8Q9M0, ARGJ_MALGO ;
DR   Q8TK55, ARGJ_METAC ;  Q607S6, ARGJ_METCA ;  Q8TX15, ARGJ_METKA ;
DR   A4FXT1, ARGJ_METM5 ;  A9AB46, ARGJ_METM6 ;  A6VFI9, ARGJ_METM7 ;
DR   Q8PZL8, ARGJ_METMA ;  P62065, ARGJ_METMP ;  O26284, ARGJ_METTH ;
DR   A6UN66, ARGJ_METVS ;  P63572, ARGJ_MYCBO ;  Q9CC14, ARGJ_MYCLE ;
DR   P62063, ARGJ_MYCPA ;  P63571, ARGJ_MYCTU ;  C7YUB3, ARGJ_NECH7 ;
DR   Q5F7I3, ARGJ_NEIG1 ;  P38434, ARGJ_NEIGO ;  P63573, ARGJ_NEIMA ;
DR   P63574, ARGJ_NEIMB ;  A1DF20, ARGJ_NEOFI ;  A7UWD5, ARGJ_NEUCR ;
DR   Q82SU1, ARGJ_NITEU ;  Q3J7A0, ARGJ_NITOC ;  Q3SVN6, ARGJ_NITWN ;
DR   Q5YYF8, ARGJ_NOCFA ;  Q8CUN1, ARGJ_OCEIH ;  B8AL33, ARGJ_ORYSI ;
DR   Q10N79, ARGJ_ORYSJ ;  A4S1K1, ARGJ_OSTLU ;  C1H986, ARGJ_PARBA ;
DR   C1GEZ1, ARGJ_PARBD ;  C0SCV8, ARGJ_PARBP ;  Q3A246, ARGJ_PELCD ;
DR   B6HQD4, ARGJ_PENCW ;  B6QFZ6, ARGJ_PENMQ ;  D0N1U4, ARGJ_PHYIN ;
DR   A9SLE5, ARGJ_PHYPA ;  A5DAF0, ARGJ_PICGU ;  C4R3R8, ARGJ_PICPG ;
DR   A3LWC0, ARGJ_PICST ;  B2B4X6, ARGJ_PODAN ;  D3AXF4, ARGJ_POLPA ;
DR   B9NAN0, ARGJ_POPTR ;  B8PH83, ARGJ_POSPM ;  Q7VEF9, ARGJ_PROMA ;
DR   Q7V436, ARGJ_PROMM ;  Q7V3M5, ARGJ_PROMP ;  Q46I07, ARGJ_PROMT ;
DR   Q48EG7, ARGJ_PSE14 ;  Q4K7C2, ARGJ_PSEF5 ;  Q3K7U0, ARGJ_PSEPF ;
DR   Q4ZNZ9, ARGJ_PSEU2 ;  Q4FSF9, ARGJ_PSYA2 ;  B2VVA8, ARGJ_PYRTR ;
DR   Q8XVJ7, ARGJ_RALSO ;  Q98G72, ARGJ_RHILO ;  Q92MJ1, ARGJ_RHIME ;
DR   Q7UUJ7, ARGJ_RHOBA ;  P96426, ARGJ_RHOFA ;  P62064, ARGJ_RHOPA ;
DR   B9SZB6, ARGJ_RICCO ;  B6JYD2, ARGJ_SCHJY ;  O94346, ARGJ_SCHPO ;
DR   Q5LWL6, ARGJ_SILPO ;  C5WPC2, ARGJ_SORBI ;  D1ZHR9, ARGJ_SORMK ;
DR   Q5HJJ0, ARGJ_STAAC ;  P63575, ARGJ_STAAM ;  P63576, ARGJ_STAAN ;
DR   Q6GKC3, ARGJ_STAAR ;  Q6GCU3, ARGJ_STAAS ;  Q8NYM7, ARGJ_STAAW ;
DR   Q5HP22, ARGJ_STAEQ ;  Q8CSF9, ARGJ_STAES ;  Q4A0N0, ARGJ_STAS1 ;
DR   Q828A5, ARGJ_STRAW ;  Q9LCS7, ARGJ_STRCL ;  Q8DV45, ARGJ_STRMU ;
DR   Q5M122, ARGJ_STRT1 ;  Q5M5L0, ARGJ_STRT2 ;  Q67KC5, ARGJ_SYMTH ;
DR   Q5MZY1, ARGJ_SYNP6 ;  Q7U3S6, ARGJ_SYNPX ;  P74122, ARGJ_SYNY3 ;
DR   B8M9V7, ARGJ_TALSN ;  B8BVB6, ARGJ_THAPS ;  Q8DHN4, ARGJ_THEEB ;
DR   Q47N80, ARGJ_THEFY ;  Q9X2A3, ARGJ_THEMA ;  Q9Z4S1, ARGJ_THENN ;
DR   Q5SJ18, ARGJ_THET8 ;  Q8R7B9, ARGJ_THETN ;  Q3SMQ9, ARGJ_THIDA ;
DR   C4JMY4, ARGJ_UNCRE ;  P0CH65, ARGJ_USTMA ;  A7TPS8, ARGJ_VANPO ;
DR   C9S923, ARGJ_VERA1 ;  A5AEC8, ARGJ_VITVI ;  Q7MAC9, ARGJ_WOLSU ;
DR   Q6C627, ARGJ_YARLI ;  B3LLV5, ARGJ_YEAS1 ;  C7GL62, ARGJ_YEAS2 ;
DR   B5VPI9, ARGJ_YEAS6 ;  A6ZMC1, ARGJ_YEAS7 ;  C8ZER4, ARGJ_YEAS8 ;
DR   Q04728, ARGJ_YEAST ;  C5E3Y4, ARGJ_ZYGRC ;  Q5NP13, ARGJ_ZYMMO ;
DR   A6RBX7, NAGS_AJECN ;  Q75A07, NAGS_ASHGO ;  A1C6J2, NAGS_ASPCL ;
DR   B0XSH8, NAGS_ASPFC ;  B8NG97, NAGS_ASPFN ;  Q4X122, NAGS_ASPFU ;
DR   A2QGF0, NAGS_ASPNC ;  Q2UES9, NAGS_ASPOR ;  Q0CY06, NAGS_ASPTN ;
DR   A6SG85, NAGS_BOTFB ;  Q59MB6, NAGS_CANAL ;  B9W7S3, NAGS_CANDC ;
DR   Q6FS75, NAGS_CANGA ;  Q1DNE1, NAGS_COCIM ;  A8N2M6, NAGS_COPC7 ;
DR   P0CM19, NAGS_CRYNB ;  P0CM18, NAGS_CRYNJ ;  Q6BZ43, NAGS_DEBHA ;
DR   Q5B0R3, NAGS_EMENI ;  Q8N159, NAGS_HUMAN ;  Q6CRT7, NAGS_KLULA ;
DR   B0CR45, NAGS_LACBS ;  A5DWN5, NAGS_LODEL ;  A4RKF7, NAGS_MAGO7 ;
DR   Q8R4H7, NAGS_MOUSE ;  A1DH62, NAGS_NEOFI ;  Q1K8F6, NAGS_NEUCR ;
DR   B6H6F3, NAGS_PENCW ;  B6QS64, NAGS_PENMQ ;  Q0U6Q5, NAGS_PHANO ;
DR   A5DA88, NAGS_PICGU ;  Q595W7, NAGS_PICPA ;  A3GG03, NAGS_PICST ;
DR   B2B2C5, NAGS_PODAN ;  B2WME0, NAGS_PYRTR ;  B6JWC1, NAGS_SCHJY ;
DR   O94330, NAGS_SCHPO ;  A7F8R0, NAGS_SCLS1 ;  B8M3T8, NAGS_TALSN ;
DR   A7TQL5, NAGS_VANPO ;  Q6CEE1, NAGS_YARLI ;  B3LQ40, NAGS_YEAS1 ;
DR   A6ZPQ2, NAGS_YEAS7 ;  P40360, NAGS_YEAST ;
//
ID   2.3.1.2
DE   Imidazole N-acetyltransferase.
AN   Imidazole acetylase.
CA   Acetyl-CoA + imidazole = CoA + N-acetylimidazole.
CC   -!- Also acts with propanoyl-CoA.
//
ID   2.3.1.3
DE   Glucosamine N-acetyltransferase.
AN   Glucosamine acetylase.
CA   Acetyl-CoA + D-glucosamine = CoA + N-acetyl-D-glucosamine.
//
ID   2.3.1.4
DE   Glucosamine-phosphate N-acetyltransferase.
AN   Aminodeoxyglucosephosphate acetyltransferase.
AN   D-glucosamine-6-P N-acetyltransferase.
AN   Glucosamine 6-phosphate acetylase.
AN   Glucosamine 6-phosphate N-acetyltransferase.
AN   Glucosamine-6-phosphate acetylase.
AN   N-acetylglucosamine-6-phosphate synthase.
AN   Phosphoglucosamine acetylase.
AN   Phosphoglucosamine N-acetylase.
AN   Phosphoglucosamine transacetylase.
CA   Acetyl-CoA + D-glucosamine 6-phosphate = CoA + N-acetyl-D-glucosamine
CA   6-phosphate.
DR   Q17427, GNA1_CAEEL ;  O93806, GNA1_CANAL ;  Q54WR8, GNA1_DICDI ;
DR   Q9VAI0, GNA1_DROME ;  Q96EK6, GNA1_HUMAN ;  Q5UPZ9, GNA1_MIMIV ;
DR   Q9JK38, GNA1_MOUSE ;  Q5RAL9, GNA1_PONAB ;  O13738, GNA1_SCHPO ;
DR   P43577, GNA1_YEAST ;
//
ID   2.3.1.5
DE   Arylamine N-acetyltransferase.
AN   Arylamine acetylase.
CA   Acetyl-CoA + an arylamine = CoA + an N-acetylarylamine.
CC   -!- Wide specificity for aromatic amines, including serotonin; also
CC       catalyzes acetyl-transfer between arylamines without CoA.
DR   Q1JPA6, ARY1_BOVIN ;  P13913, ARY1_CHICK ;  Q54IU9, ARY1_DICDI ;
DR   O62696, ARY1_FELCA ;  P18440, ARY1_HUMAN ;  P50292, ARY1_MESAU ;
DR   P50294, ARY1_MOUSE ;  P18605, ARY1_RABIT ;  P50297, ARY1_RAT   ;
DR   P13914, ARY2_CHICK ;  Q54IU8, ARY2_DICDI ;  P11245, ARY2_HUMAN ;
DR   Q7YRG5, ARY2_MACMU ;  P50293, ARY2_MESAU ;  P50295, ARY2_MOUSE ;
DR   P11246, ARY2_RABIT ;  P50298, ARY2_RAT   ;  Q54IU7, ARY3_DICDI ;
DR   P50296, ARY3_MOUSE ;  P12275, ARYL_CHICK ;  P0A5L9, NAT_MYCBO  ;
DR   O86309, NAT_MYCSM  ;  P0A5L8, NAT_MYCTU  ;
//
ID   2.3.1.6
DE   Choline O-acetyltransferase.
AN   CHOACTase.
AN   Choline acetylase.
CA   Acetyl-CoA + choline = CoA + O-acetylcholine.
CC   -!- Propanoyl-CoA can act, more slowly, in place of acetyl-CoA.
PR   PROSITE; PDOC00402;
DR   P32756, CLAT_CAEEL ;  Q90YJ9, CLAT_CHICK ;  B2ZGJ1, CLAT_DANRE ;
DR   P07668, CLAT_DROME ;  P28329, CLAT_HUMAN ;  Q03059, CLAT_MOUSE ;
DR   P13222, CLAT_PIG   ;  P32738, CLAT_RAT   ;
//
ID   2.3.1.7
DE   Carnitine O-acetyltransferase.
AN   Carnitine acetylase.
CA   Acetyl-CoA + carnitine = CoA + O-acetylcarnitine.
CC   -!- Also acts on propanoyl-CoA and butanoyl-CoA (cf. EC 2.3.1.21 and
CC       EC 2.3.1.137).
PR   PROSITE; PDOC00402;
DR   P80235, CACM_YEAST ;  Q00614, CACP_CANTR ;  P52826, CACP_COLLI ;
DR   P43155, CACP_HUMAN ;  P47934, CACP_MOUSE ;  Q704S8, CACP_RAT   ;
DR   P32796, CACP_YEAST ;  P40017, YAT2_YEAST ;
//
ID   2.3.1.8
DE   Phosphate acetyltransferase.
AN   Phosphoacylase.
AN   Phosphotransacetylase.
CA   Acetyl-CoA + phosphate = CoA + acetyl phosphate.
CC   -!- Also acts with other short-chain acyl-CoAs.
DR   P39646, PTAS_BACSU ;  O51535, PTAS_BORBU ;  P71103, PTAS_CLOAB ;
DR   O52593, PTAS_CLOTH ;  P77844, PTAS_CORGL ;  Q9ZKU4, PTAS_HELPJ ;
DR   P38503, PTAS_METTE ;  Q49112, PTAS_MYCCT ;  P47541, PTAS_MYCGE ;
DR   P75359, PTAS_MYCPN ;  P39197, PTAS_PARDE ;  Q9X448, PTAS_RHIME ;
DR   Q4UNB1, PTAS_RICFE ;  Q9ZE39, PTAS_RICPR ;  Q68XX7, PTAS_RICTY ;
DR   Q5HI88, PTAS_STAAC ;  P65862, PTAS_STAAM ;  P99092, PTAS_STAAN ;
DR   Q6GJ80, PTAS_STAAR ;  Q6GBP8, PTAS_STAAS ;  Q8NXW4, PTAS_STAAW ;
DR   Q5HRF7, PTAS_STAEQ ;  Q8CQ62, PTAS_STAES ;  Q9X0L4, PTAS_THEMA ;
DR   Q59330, PTAS_THETC ;  O83132, PTAS_TREPA ;  Q6FEP2, PTA_ACIAD  ;
DR   P57273, PTA_BUCAI  ;  Q8K9W5, PTA_BUCAP  ;  Q89AS7, PTA_BUCBP  ;
DR   Q1J2D0, PTA_DEIGD  ;  Q9RY77, PTA_DEIRA  ;  Q726S7, PTA_DESVH  ;
DR   P0A9M8, PTA_ECOLI  ;  P45107, PTA_HAEIN  ;  P96254, PTA_MYCTU  ;
DR   Q820S1, PTA_NITEU  ;  Q9I5A5, PTA_PSEAE  ;  Q88PS4, PTA_PSEPK  ;
DR   Q8ZND6, PTA_SALTY  ;  P0A9M9, PTA_SHIFL  ;  Q82JD2, PTA_STRAW  ;
DR   Q8CJR5, PTA_STRCO  ;  P73662, PTA_SYNY3  ;  Q9KT08, PTA_VIBCH  ;
DR   Q7CJ96, PTA_YERPE  ;
//
ID   2.3.1.9
DE   Acetyl-CoA C-acetyltransferase.
AN   Acetoacetyl-CoA thiolase.
CA   2 acetyl-CoA = CoA + acetoacetyl-CoA.
PR   PROSITE; PDOC00092;
DR   P76461, ATOB_ECOLI ;  P44873, ATOB_HAEIN ;  Q9I2A8, ATOB_PSEAE ;
DR   Q12598, THIA_CANTR ;  Q04677, THIB_CANTR ;  Q8S4Y1, THIC1_ARATH;
DR   Q9FIK7, THIC2_ARATH;  Q9BWD1, THIC_HUMAN ;  Q8CAY6, THIC_MOUSE ;
DR   Q5XI22, THIC_RAT   ;  Q86AD9, THIL1_DICDI;  Q6NU46, THILA_XENLA;
DR   Q6GN02, THILB_XENLA;  P45369, THIL_ALLVD ;  Q29RZ0, THIL_BOVIN ;
DR   Q9ZHI1, THIL_CHRVO ;  P14611, THIL_CUPNH ;  Q6AZA0, THIL_DANRE ;
DR   P24752, THIL_HUMAN ;  Q8HXY6, THIL_MACFA ;  Q8QZT1, THIL_MOUSE ;
DR   P66927, THIL_MYCBO ;  P46707, THIL_MYCLE ;  A0R1Y7, THIL_MYCS2 ;
DR   P66926, THIL_MYCTU ;  P54810, THIL_PARDE ;  P14610, THIL_PIG   ;
DR   P17764, THIL_RAT   ;  P50174, THIL_RHIME ;  P10551, THIL_SACBA ;
DR   Q9UQW6, THIL_SCHPO ;  P45363, THIL_THIVI ;  Q5BKN8, THIL_XENTR ;
DR   Q6L8K7, THIL_YARLI ;  P41338, THIL_YEAST ;  P07097, THIL_ZOORA ;
DR   P45359, THLA_CLOAB ;  Q18AR0, THLA_CLOD6 ;  Q2FJQ9, THLA_STAA3 ;
DR   Q2G124, THLA_STAA8 ;  Q2YVF5, THLA_STAAB ;  Q5HIU0, THLA_STAAC ;
DR   Q99WM3, THLA_STAAM ;  Q7A7L2, THLA_STAAN ;  Q6GJW4, THLA_STAAR ;
DR   Q6GCB8, THLA_STAAS ;  Q8NY95, THLA_STAAW ;  Q5HS07, THLA_STAEQ ;
DR   Q8CQN7, THLA_STAES ;  P45855, THL_BACSU  ;  P45362, THL_CLODI  ;
DR   P81347, THL_CLOPA  ;  Q46939, YQEF_ECOLI ;
//
ID   2.3.1.10
DE   Hydrogen-sulfide S-acetyltransferase.
CA   Acetyl-CoA + hydrogen sulfide = CoA + thioacetate.
//
ID   2.3.1.11
DE   Thioethanolamine S-acetyltransferase.
AN   Thioethanolamine acetyltransferase.
AN   Thioltransacetylase B.
CA   Acetyl-CoA + 2-aminoethanethiol = CoA + S-(2-aminoethyl)thioacetate.
CC   -!- 2-sulfanylethanol (2-mercaptoethanol) can act as a substrate.
//
ID   2.3.1.12
DE   Dihydrolipoyllysine-residue acetyltransferase.
AN   Acetyl-CoA:dihydrolipoamide S-acetyltransferase.
AN   Dihydrolipoamide S-acetyltransferase.
AN   Dihydrolipoate acetyltransferase.
AN   Dihydrolipoic transacetylase.
AN   Dihydrolipoyl acetyltransferase.
AN   Lipoate acetyltransferase.
AN   Lipoate transacetylase.
AN   Lipoic acetyltransferase.
AN   Lipoic acid acetyltransferase.
AN   Lipoic transacetylase.
AN   Lipoylacetyltransferase.
AN   Thioltransacetylase A.
AN   Transacetylase X.
CA   Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-
CA   (S-acetyldihydrolipoyl)lysine.
CC   -!- A multimer (24-mer or 60-mer, depending on the source) of this enzyme
CC       forms the core of the pyruvate dehydrogenase multienzyme complex,
CC       and binds tightly both EC 1.2.4.1 and EC 1.8.1.4.
CC   -!- The lipoyl group of this enzyme is reductively acetylated by
CC       EC 1.2.4.1, and the only observed direction catalyzed by EC 2.3.1.12
CC       is that where the acetyl group is passed to coenzyme A.
DR   O31550, ACOC_BACSU ;  P27747, ACOC_CUPNH ;  Q59695, ACOC_PSEPU ;
DR   P35489, ODP2_ACHLA ;  P10802, ODP2_AZOVI ;  P21883, ODP2_BACSU ;
DR   P11180, ODP2_BOVIN ;  P57302, ODP2_BUCAI ;  Q8K9T8, ODP2_BUCAP ;
DR   Q89AQ9, ODP2_BUCBP ;  Q19749, ODP2_CAEEL ;  Q59098, ODP2_CUPNH ;
DR   P36413, ODP2_DICDI ;  P06959, ODP2_ECOLI ;  P11961, ODP2_GEOSE ;
DR   P45118, ODP2_HAEIN ;  P10515, ODP2_HUMAN ;  Q6ABX9, ODP2_LEIXX ;
DR   P86197, ODP2_MESAU ;  Q8BMF4, ODP2_MOUSE ;  Q49110, ODP2_MYCCT ;
DR   P47514, ODP2_MYCGE ;  P75392, ODP2_MYCPN ;  P20285, ODP2_NEUCR ;
DR   Q59638, ODP2_PSEAE ;  P08461, ODP2_RAT   ;  Q9R9N3, ODP2_RHIME ;
DR   Q1RJT3, ODP2_RICBR ;  Q92HK7, ODP2_RICCN ;  Q4ULG1, ODP2_RICFE ;
DR   Q9ZD20, ODP2_RICPR ;  Q68WK6, ODP2_RICTY ;  O59816, ODP2_SCHPO ;
DR   P81421, ODP2_SOLTU ;  Q5HGY9, ODP2_STAAC ;  P65635, ODP2_STAAM ;
DR   P65636, ODP2_STAAN ;  Q6GHZ0, ODP2_STAAR ;  Q6GAB9, ODP2_STAAS ;
DR   Q59821, ODP2_STAAU ;  Q8NX76, ODP2_STAAW ;  Q5HQ74, ODP2_STAEQ ;
DR   Q8CT13, ODP2_STAES ;  P12695, ODP2_YEAST ;  O66119, ODP2_ZYMMO ;
DR   P81420, ODP3_SOLTU ;  Q0WQF7, OPD21_ARATH;  Q8RWN9, OPD22_ARATH;
DR   Q5M729, OPD23_ARATH;
//
ID   2.3.1.13
DE   Glycine N-acyltransferase.
CA   Acyl-CoA + glycine = CoA + N-acylglycine.
CC   -!- The CoA derivatives of a number of aliphatic and aromatic acids,
CC       but not phenylacetyl-CoA or (indol-3-yl)acetyl-CoA, can act as donor.
CC   -!- Not identical with EC 2.3.1.68 or EC 2.3.1.71.
DR   Q5FW57, GLYAL_MOUSE;  Q2KIR7, GLYAT_BOVIN;  Q6IB77, GLYAT_HUMAN;
DR   Q91XE0, GLYAT_MOUSE;  Q5RFP0, GLYAT_PONAB;  Q5PQT3, GLYAT_RAT  ;
DR   Q969I3, GLYL1_HUMAN;  Q8WU03, GLYL2_HUMAN;  Q9DCY0, KEG1_MOUSE ;
DR   Q9Z2Y0, KEG1_RAT   ;
//
ID   2.3.1.14
DE   Glutamine N-phenylacetyltransferase.
CA   Phenylacetyl-CoA + L-glutamine = CoA + alpha-N-phenylacetyl-L-glutamine.
//
ID   2.3.1.15
DE   Glycerol-3-phosphate O-acyltransferase.
CA   Acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol
CA   3-phosphate.
CC   -!- Acyl-[acyl-carrier-protein] can also act as acyl donor.
CC   -!- Acts only with derivatives of fatty acids of chain length above
CC       C(10).
DR   Q9SHJ5, GPAT1_ARATH;  Q5GJ77, GPAT1_BOVIN;  Q9HCL2, GPAT1_HUMAN;
DR   Q61586, GPAT1_MOUSE;  P97564, GPAT1_RAT  ;  Q9FZ22, GPAT2_ARATH;
DR   Q6NUI2, GPAT2_HUMAN;  Q14DK4, GPAT2_MOUSE;  Q9SYJ2, GPAT3_ARATH;
DR   Q5ZLL8, GPAT3_CHICK;  Q6DG38, GPAT3_DANRE;  Q53EU6, GPAT3_HUMAN;
DR   Q8C0N2, GPAT3_MOUSE;  Q4V8J4, GPAT3_RAT  ;  Q68F37, GPAT3_XENLA;
DR   Q9LMM0, GPAT4_ARATH;  A3FPG8, GPAT4_BOVIN;  Q86UL3, GPAT4_HUMAN;
DR   Q8K2C8, GPAT4_MOUSE;  Q5R6J7, GPAT4_PONAB;  Q9CAY3, GPAT5_ARATH;
DR   O80437, GPAT6_ARATH;  Q9LHS7, GPAT7_ARATH;  Q5XF03, GPAT8_ARATH;
DR   P32784, GPT1_YEAST ;  P36148, GPT2_YEAST ;  A3KGT9, GPT3L_DANRE;
DR   A3N1B3, PLSB_ACTP2 ;  B3GXZ3, PLSB_ACTP7 ;  B0BQ47, PLSB_ACTPJ ;
DR   A6VQ68, PLSB_ACTSZ ;  A0KEQ0, PLSB_AERHH ;  B6ENU1, PLSB_ALISL ;
DR   B4S1W8, PLSB_ALTMD ;  Q43307, PLSB_ARATH ;  Q1LU65, PLSB_BAUCH ;
DR   Q22949, PLSB_CAEEL ;  Q42713, PLSB_CARTI ;  Q48AL2, PLSB_COLP3 ;
DR   P10349, PLSB_CUCMO ;  Q39639, PLSB_CUCSA ;  A7ZUR3, PLSB_ECO24 ;
DR   B7UPK2, PLSB_ECO27 ;  B7MJ31, PLSB_ECO45 ;  B7LAY9, PLSB_ECO55 ;
DR   P58130, PLSB_ECO57 ;  B5Z182, PLSB_ECO5E ;  B7NS05, PLSB_ECO7I ;
DR   B7N2P8, PLSB_ECO81 ;  B7M7V4, PLSB_ECO8A ;  C5A134, PLSB_ECOBW ;
DR   B1XC40, PLSB_ECODH ;  A8A7E1, PLSB_ECOHS ;  A1AIL8, PLSB_ECOK1 ;
DR   P0A7A8, PLSB_ECOL6 ;  B1IUL1, PLSB_ECOLC ;  P0A7A7, PLSB_ECOLI ;
DR   B7NFY5, PLSB_ECOLU ;  B6I5Q6, PLSB_ECOSE ;  B1LPK6, PLSB_ECOSM ;
DR   Q1R3P5, PLSB_ECOUT ;  C5B706, PLSB_EDWI9 ;  A4W5F4, PLSB_ENT38 ;
DR   Q6D9I7, PLSB_ERWCT ;  B7LL13, PLSB_ESCF3 ;  Q7VNI5, PLSB_HAEDU ;
DR   Q4QMF0, PLSB_HAEI8 ;  A5UDX7, PLSB_HAEIE ;  A5UHQ2, PLSB_HAEIG ;
DR   P44857, PLSB_HAEIN ;  B8F321, PLSB_HAEPS ;  Q0I2G8, PLSB_HAES1 ;
DR   C4K8M7, PLSB_HAMD5 ;  B5XXZ1, PLSB_KLEP3 ;  A6TGV0, PLSB_KLEP7 ;
DR   Q7TYH5, PLSB_MYCBO ;  A1KLH6, PLSB_MYCBP ;  C1AEU7, PLSB_MYCBT ;
DR   B8ZRA3, PLSB_MYCLB ;  Q9X7B0, PLSB_MYCLE ;  B2HNJ0, PLSB_MYCMM ;
DR   A5U5H8, PLSB_MYCTA ;  O53207, PLSB_MYCTU ;  Q9CLN7, PLSB_PASMU ;
DR   P30706, PLSB_PEA   ;  C6DKD0, PLSB_PECCP ;  Q43822, PLSB_PHAVU ;
DR   Q7MZB7, PLSB_PHOLL ;  B4EYR5, PLSB_PROMH ;  Q48F46, PLSB_PSE14 ;
DR   Q15MZ1, PLSB_PSEA6 ;  A6V1B5, PLSB_PSEA7 ;  B7V2U0, PLSB_PSEA8 ;
DR   Q02RE5, PLSB_PSEAB ;  Q9HXW7, PLSB_PSEAE ;  Q1I610, PLSB_PSEE4 ;
DR   Q4KHJ1, PLSB_PSEF5 ;  C3K4R1, PLSB_PSEFS ;  Q3IF27, PLSB_PSEHT ;
DR   A4XWX9, PLSB_PSEMY ;  A5W867, PLSB_PSEP1 ;  Q3KHC9, PLSB_PSEPF ;
DR   B0KS79, PLSB_PSEPG ;  Q88MQ0, PLSB_PSEPK ;  B1JBS6, PLSB_PSEPW ;
DR   Q886Q7, PLSB_PSESM ;  Q4ZWU3, PLSB_PSEU2 ;  B5F1Q4, PLSB_SALA4 ;
DR   A9MGP8, PLSB_SALAR ;  Q57GZ2, PLSB_SALCH ;  B5FQQ9, PLSB_SALDC ;
DR   B5QZ60, PLSB_SALEP ;  B5R7T4, PLSB_SALG2 ;  B4TDL8, PLSB_SALHS ;
DR   B4T1T0, PLSB_SALNS ;  Q5PL16, PLSB_SALPA ;  A9N1L4, PLSB_SALPB ;
DR   C0Q4E0, PLSB_SALPC ;  B5BJV8, PLSB_SALPK ;  B4TQQ3, PLSB_SALSV ;
DR   Q8Z1T6, PLSB_SALTI ;  Q8ZKH9, PLSB_SALTY ;  A8GKB6, PLSB_SERP5 ;
DR   A1SBC6, PLSB_SHEAM ;  B8ECL8, PLSB_SHEB2 ;  A3CYX8, PLSB_SHEB5 ;
DR   A6WU04, PLSB_SHEB8 ;  A9KUW7, PLSB_SHEB9 ;  Q12ID7, PLSB_SHEDO ;
DR   Q089E1, PLSB_SHEFN ;  B0TNU4, PLSB_SHEHH ;  A3QIU8, PLSB_SHELP ;
DR   Q8E8Q9, PLSB_SHEON ;  A8H9R9, PLSB_SHEPA ;  A4YC03, PLSB_SHEPC ;
DR   B8CUW9, PLSB_SHEPW ;  A0L2D7, PLSB_SHESA ;  A8FPP1, PLSB_SHESH ;
DR   Q0HDL6, PLSB_SHESM ;  Q0HPW7, PLSB_SHESR ;  A1RE94, PLSB_SHESW ;
DR   B1KM69, PLSB_SHEWM ;  B2TX75, PLSB_SHIB3 ;  Q31TU9, PLSB_SHIBS ;
DR   Q327U8, PLSB_SHIDS ;  Q0SXQ8, PLSB_SHIF8 ;  Q7UBC6, PLSB_SHIFL ;
DR   Q3YUU3, PLSB_SHISS ;  Q2NR08, PLSB_SODGM ;  Q43869, PLSB_SPIOL ;
DR   A5F4F5, PLSB_VIBC3 ;  Q9KVP8, PLSB_VIBCH ;  C3LPT5, PLSB_VIBCM ;
DR   Q5E208, PLSB_VIBF1 ;  B5FCB3, PLSB_VIBFM ;  Q87KN0, PLSB_VIBPA ;
DR   B7VM97, PLSB_VIBSL ;  Q8DD48, PLSB_VIBVU ;  Q7MQ86, PLSB_VIBVY ;
DR   Q8PES0, PLSB_XANAC ;  Q8P3E3, PLSB_XANCP ;  B2I7N1, PLSB_XYLF2 ;
DR   Q9PEJ7, PLSB_XYLFA ;  B0U229, PLSB_XYLFM ;  Q87EJ1, PLSB_XYLFT ;
DR   A1JRU2, PLSB_YERE8 ;  A7FN98, PLSB_YERP3 ;  Q1C0T9, PLSB_YERPA ;
DR   B2K1U5, PLSB_YERPB ;  Q8ZJ18, PLSB_YERPE ;  Q1CE96, PLSB_YERPN ;
DR   A4TRU7, PLSB_YERPP ;  Q66FG9, PLSB_YERPS ;  B1JNE5, PLSB_YERPY ;
DR   A7ZRU0, PLSY_ECO24 ;  B7UIW7, PLSY_ECO27 ;  B7MAZ5, PLSY_ECO45 ;
DR   B7LGZ5, PLSY_ECO55 ;  P60784, PLSY_ECO57 ;  B5YR99, PLSY_ECO5E ;
DR   B7NJS2, PLSY_ECO7I ;  B7N0K9, PLSY_ECO81 ;  B7LZK9, PLSY_ECO8A ;
DR   C4ZQX6, PLSY_ECOBW ;  B1XG64, PLSY_ECODH ;  A8A4L4, PLSY_ECOHS ;
DR   A1AFY1, PLSY_ECOK1 ;  Q0TD47, PLSY_ECOL5 ;  P60783, PLSY_ECOL6 ;
DR   B1IRQ7, PLSY_ECOLC ;  P60782, PLSY_ECOLI ;  B7ND48, PLSY_ECOLU ;
DR   B6I430, PLSY_ECOSE ;  B1LF51, PLSY_ECOSM ;  Q1R6S2, PLSY_ECOUT ;
DR   B7LQD7, PLSY_ESCF3 ;  B5F6A3, PLSY_SALA4 ;  A9MPV6, PLSY_SALAR ;
DR   Q57JQ2, PLSY_SALCH ;  B5FHU2, PLSY_SALDC ;  B5QZ43, PLSY_SALEP ;
DR   B5REG5, PLSY_SALG2 ;  B4TI58, PLSY_SALHS ;  B4T677, PLSY_SALNS ;
DR   Q5PC79, PLSY_SALPA ;  A9N5Y5, PLSY_SALPB ;  B5BG18, PLSY_SALPK ;
DR   B4TVU1, PLSY_SALSV ;  P67162, PLSY_SALTI ;  P67161, PLSY_SALTY ;
DR   B2U1G3, PLSY_SHIB3 ;  Q31WX6, PLSY_SHIBS ;  Q32BQ6, PLSY_SHIDS ;
DR   Q0T0K4, PLSY_SHIF8 ;  P59252, PLSY_SHIFL ;  Q3YXI3, PLSY_SHISS ;
//
ID   2.3.1.16
DE   Acetyl-CoA C-acyltransferase.
AN   3-ketoacyl-CoA thiolase.
AN   Beta-ketothiolase.
CA   Acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA.
PR   PROSITE; PDOC00092;
DR   O46629, ECHB_BOVIN ;  P55084, ECHB_HUMAN ;  Q8HXX4, ECHB_MACFA ;
DR   Q99JY0, ECHB_MOUSE ;  Q5R1W7, ECHB_PANTR ;  Q60587, ECHB_RAT   ;
DR   Q6FF69, FADA_ACIAD ;  B7H1I1, FADA_ACIB3 ;  B7I3P0, FADA_ACIB5 ;
DR   B2I2J8, FADA_ACIBC ;  B0VLX5, FADA_ACIBS ;  A3M1H9, FADA_ACIBT ;
DR   B0VE46, FADA_ACIBY ;  A0KEL0, FADA_AERHH ;  A4STF3, FADA_AERS4 ;
DR   Q0VNZ7, FADA_ALCBS ;  B6EGU1, FADA_ALISL ;  O32177, FADA_BACSU ;
DR   Q1QUW9, FADA_CHRSD ;  A8ACZ3, FADA_CITK8 ;  Q489W4, FADA_COLP3 ;
DR   A7ZU50, FADA_ECO24 ;  Q8X8J4, FADA_ECO57 ;  A8A6V0, FADA_ECOHS ;
DR   A1AI32, FADA_ECOK1 ;  Q0TAL1, FADA_ECOL5 ;  Q8FBI3, FADA_ECOL6 ;
DR   P21151, FADA_ECOLI ;  Q1R467, FADA_ECOUT ;  A4WFX5, FADA_ENT38 ;
DR   Q9F0Y6, FADA_ENTCL ;  A7MQM5, FADA_ENTS8 ;  Q6DAP6, FADA_ERWCT ;
DR   B2VFE0, FADA_ERWT9 ;  B7LTZ0, FADA_ESCF3 ;  Q2SD23, FADA_HAHCH ;
DR   Q5QXH8, FADA_IDILO ;  A6TGM3, FADA_KLEP7 ;  A1TZR8, FADA_MARAV ;
DR   A6VVM8, FADA_MARMS ;  C6DI66, FADA_PECCP ;  Q7MZ91, FADA_PHOLL ;
DR   Q6LW07, FADA_PHOPR ;  Q48GW4, FADA_PSE14 ;  Q15ZF4, FADA_PSEA6 ;
DR   A6V383, FADA_PSEA7 ;  Q02PH7, FADA_PSEAB ;  Q9HZJ3, FADA_PSEAE ;
DR   Q1I7D5, FADA_PSEE4 ;  Q4KFC3, FADA_PSEF5 ;  P28790, FADA_PSEFR ;
DR   Q3IJ24, FADA_PSEHT ;  A4XSM9, FADA_PSEMY ;  Q93Q11, FADA_PSEOL ;
DR   A5W6G9, FADA_PSEP1 ;  Q3K9D9, FADA_PSEPF ;  Q88L01, FADA_PSEPK ;
DR   Q9R9W0, FADA_PSEPU ;  Q87ZB3, FADA_PSESM ;  Q4ZRA1, FADA_PSEU2 ;
DR   A4VKA4, FADA_PSEU5 ;  Q4FQC7, FADA_PSYA2 ;  Q1Q8K0, FADA_PSYCK ;
DR   A5WH98, FADA_PSYWF ;  Q21KB1, FADA_SACD2 ;  Q57HM7, FADA_SALCH ;
DR   Q5PKQ3, FADA_SALPA ;  P0A2H8, FADA_SALTI ;  P0A2H7, FADA_SALTY ;
DR   A8G8D0, FADA_SERP5 ;  A1S1I7, FADA_SHEAM ;  A3CYJ3, FADA_SHEB5 ;
DR   A6WH99, FADA_SHEB8 ;  Q12TB5, FADA_SHEDO ;  Q08A40, FADA_SHEFN ;
DR   A3Q8U3, FADA_SHELP ;  Q8EKS0, FADA_SHEON ;  A4Y1B5, FADA_SHEPC ;
DR   A0KR49, FADA_SHESA ;  Q0HPB8, FADA_SHESM ;  Q0I0T4, FADA_SHESR ;
DR   A1RDW3, FADA_SHESW ;  Q31UE3, FADA_SHIBS ;  Q32A20, FADA_SHIDS ;
DR   Q0SZ35, FADA_SHIF8 ;  Q83PG2, FADA_SHIFL ;  Q3YVC2, FADA_SHISS ;
DR   A5F464, FADA_VIBC3 ;  Q9KNI0, FADA_VIBCH ;  Q5E8X7, FADA_VIBF1 ;
DR   B5FEW7, FADA_VIBFM ;  Q87TP0, FADA_VIBPA ;  Q8DDK5, FADA_VIBVU ;
DR   Q7MQI0, FADA_VIBVY ;  A1JIG3, FADA_YERE8 ;  A7FDF1, FADA_YERP3 ;
DR   Q1C2C3, FADA_YERPA ;  Q8ZAM9, FADA_YERPE ;  Q1CNA0, FADA_YERPN ;
DR   A4TR28, FADA_YERPP ;  Q66FR9, FADA_YERPS ;  A0KK76, FADI_AERHH ;
DR   A4SMT9, FADI_AERS4 ;  B4RTU9, FADI_ALTMD ;  A8ADP1, FADI_CITK8 ;
DR   Q47ZB6, FADI_COLP3 ;  A7ZPF9, FADI_ECO24 ;  B7UFZ9, FADI_ECO27 ;
DR   B7MGV8, FADI_ECO45 ;  B7LBJ6, FADI_ECO55 ;  Q8XCN9, FADI_ECO57 ;
DR   B5YXY5, FADI_ECO5E ;  B7NP25, FADI_ECO7I ;  B7MY17, FADI_ECO81 ;
DR   B7M6M3, FADI_ECO8A ;  C4ZVN3, FADI_ECOBW ;  B1X9L5, FADI_ECODH ;
DR   A8A2L1, FADI_ECOHS ;  A1ADI9, FADI_ECOK1 ;  Q0TFA5, FADI_ECOL5 ;
DR   Q8FFG3, FADI_ECOL6 ;  B1IXA4, FADI_ECOLC ;  P76503, FADI_ECOLI ;
DR   B7N5V3, FADI_ECOLU ;  B6I6Q5, FADI_ECOSE ;  B1LME8, FADI_ECOSM ;
DR   Q1R971, FADI_ECOUT ;  A4WCW7, FADI_ENT38 ;  A7MH80, FADI_ENTS8 ;
DR   Q6D2L6, FADI_ERWCT ;  B2VJ10, FADI_ERWT9 ;  B7LLC9, FADI_ESCF3 ;
DR   Q5QXN5, FADI_IDILO ;  B5XVW1, FADI_KLEP3 ;  A6TC20, FADI_KLEP7 ;
DR   C6DAL8, FADI_PECCP ;  Q7N287, FADI_PHOLL ;  Q6LTK4, FADI_PHOPR ;
DR   Q15VA3, FADI_PSEA6 ;  Q3IEE3, FADI_PSEHT ;  B5EZS0, FADI_SALA4 ;
DR   A9MJ36, FADI_SALAR ;  Q57LW5, FADI_SALCH ;  B5FPN2, FADI_SALDC ;
DR   B5R3S0, FADI_SALEP ;  B4TCA9, FADI_SALHS ;  B4SZR1, FADI_SALNS ;
DR   Q5PCX7, FADI_SALPA ;  A9N452, FADI_SALPB ;  C0PZX5, FADI_SALPC ;
DR   B5BBA0, FADI_SALPK ;  B4TQC3, FADI_SALSV ;  Q8Z4Y9, FADI_SALTI ;
DR   Q8ZNA6, FADI_SALTY ;  A8GH87, FADI_SERP5 ;  A1S7L7, FADI_SHEAM ;
DR   B8EE97, FADI_SHEB2 ;  A3D685, FADI_SHEB5 ;  A6WQ26, FADI_SHEB8 ;
DR   A9KTW7, FADI_SHEB9 ;  Q12P12, FADI_SHEDO ;  Q07ZP7, FADI_SHEFN ;
DR   B0TL22, FADI_SHEHH ;  A3QFP4, FADI_SHELP ;  Q8ECP6, FADI_SHEON ;
DR   A8H5T2, FADI_SHEPA ;  A4Y898, FADI_SHEPC ;  B8CPY7, FADI_SHEPW ;
DR   A0KV75, FADI_SHESA ;  A8FTR6, FADI_SHESH ;  Q0HKD2, FADI_SHESM ;
DR   Q0HWN4, FADI_SHESR ;  A1RI91, FADI_SHESW ;  B1KKT1, FADI_SHEWM ;
DR   B2TWV5, FADI_SHIB3 ;  Q31YB6, FADI_SHIBS ;  Q32DJ3, FADI_SHIDS ;
DR   Q0T2E5, FADI_SHIF8 ;  Q83K95, FADI_SHIFL ;  Q3YZM1, FADI_SHISS ;
DR   A5F2P1, FADI_VIBC3 ;  Q9KT59, FADI_VIBCH ;  Q5E3U0, FADI_VIBF1 ;
DR   B5FGB5, FADI_VIBFM ;  Q87MM2, FADI_VIBPA ;  Q8DB48, FADI_VIBVU ;
DR   Q7MIS4, FADI_VIBVY ;  A1JK23, FADI_YERE8 ;  A7FGK0, FADI_YERP3 ;
DR   Q1C659, FADI_YERPA ;  B2K8J6, FADI_YERPB ;  Q8ZD46, FADI_YERPE ;
DR   A9R7W9, FADI_YERPG ;  Q1CHK1, FADI_YERPN ;  A4TM83, FADI_YERPP ;
DR   Q668V0, FADI_YERPS ;  B1JGG1, FADI_YERPY ;  Q8LF48, THIK1_ARATH;
DR   Q56WD9, THIK2_ARATH;  Q570C8, THIK5_ARATH;  P33290, THIKA_CANTR;
DR   Q921H8, THIKA_MOUSE;  P21775, THIKA_RAT  ;  P33291, THIKB_CANTR;
DR   Q8VCH0, THIKB_MOUSE;  P07871, THIKB_RAT  ;  Q8SVA6, THIK_ENCCU ;
DR   P09110, THIK_HUMAN ;  Q05493, THIK_YARLI ;  P27796, THIK_YEAST ;
DR   Q3T0R7, THIM_BOVIN ;  P42765, THIM_HUMAN ;  Q8BWT1, THIM_MOUSE ;
DR   Q5RES5, THIM_PONAB ;  P13437, THIM_RAT   ;
//
ID   2.3.1.17
DE   Aspartate N-acetyltransferase.
CA   Acetyl-CoA + L-aspartate = CoA + N-acetyl-L-aspartate.
DR   A4IGD2, NAT8L_DANRE;  Q8N9F0, NAT8L_HUMAN;  Q3UGX3, NAT8L_MOUSE;
DR   D3ZVU9, NAT8L_RAT  ;  A4II32, NAT8L_XENTR;
//
ID   2.3.1.18
DE   Galactoside O-acetyltransferase.
AN   Thiogalactoside acetyltransferase.
CA   Acetyl-CoA + a beta-D-galactoside = CoA + a 6-acetyl-beta-D-galactoside.
CC   -!- Acts on thiogalactosides and phenylgalactoside.
PR   PROSITE; PDOC00094;
DR   P07464, THGA_ECOLI ;  P52984, THGA_LACLA ;
//
ID   2.3.1.19
DE   Phosphate butyryltransferase.
AN   Phosphotransbutyrylase.
CA   Butanoyl-CoA + phosphate = CoA + butanoylphosphate.
DR   P54530, PTB_BACSU  ;  P58255, PTB_CLOAB  ;  Q05624, PTB_CLOB8  ;
//
ID   2.3.1.20
DE   Diacylglycerol O-acyltransferase.
AN   Diglyceride acyltransferase.
CA   Acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol.
CC   -!- Palmitoyl-CoA and other long-chain acyl-CoAs can act as donors.
DR   Q75BY0, DGA1_ASHGO ;  O74850, DGA1_SCHPO ;  Q08650, DGA1_YEAST ;
DR   Q9SLD2, DGAT1_ARATH;  Q8MK44, DGAT1_BOVIN;  Q9GMF1, DGAT1_CHLAE;
DR   Q55BH9, DGAT1_DICDI;  O75907, DGAT1_HUMAN;  Q9Z2A7, DGAT1_MOUSE;
DR   Q9ERM3, DGAT1_RAT  ;  Q9ASU1, DGAT2_ARATH;  Q70VZ8, DGAT2_BOVIN;
DR   Q4V9F0, DGAT2_DANRE;  Q54GC1, DGAT2_DICDI;  Q96PD7, DGAT2_HUMAN;
DR   Q9DCV3, DGAT2_MOUSE;  Q5FVP8, DGAT2_RAT  ;  Q6PAZ3, DGAT2_XENLA;
DR   Q6P342, DGAT2_XENTR;  Q96UY2, DGT2A_UMBRA;  Q96UY1, DGT2B_UMBRA;
DR   Q86VF5, MOGT3_HUMAN;  P0A650, TGS1_MYCTU ;  P67210, TGS2_MYCTU ;
DR   O05879, TGS3_MYCTU ;  P67208, TGS4_MYCTU ;  Q93ZR6, WSD1_ARATH ;
DR   Q8GGG1, WSD_ACIAD  ;  P71694, Y1425_MYCTU;  O06795, Y1760_MYCTU;
DR   P96403, Y221_MYCTU ;  P67206, Y2285_MYCTU;  P67207, Y2306_MYCBO;
DR   O53209, Y2484_MYCTU;  O53304, Y3087_MYCTU;  P67209, Y3115_MYCBO;
DR   P0A651, Y3154_MYCBO;  O50400, Y3371_MYCTU;  O06343, Y3480_MYCTU;
DR   O69707, Y3740_MYCTU;  P67211, Y3761_MYCBO;  P67204, Y895_MYCTU ;
DR   P67205, Y919_MYCBO ;
//
ID   2.3.1.21
DE   Carnitine O-palmitoyltransferase.
CA   Palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine.
CC   -!- Broad specificity to acyl group, over the range C(8) to C(18);
CC       optimal activity with palmitoyl-CoA (cf. EC 2.3.1.7 and
CC       EC 2.3.1.137).
PR   PROSITE; PDOC00402;
DR   Q68Y62, CPT1A_HORSE;  P50416, CPT1A_HUMAN;  P97742, CPT1A_MOUSE;
DR   P32198, CPT1A_RAT  ;  Q58DK1, CPT1B_BOVIN;  Q92523, CPT1B_HUMAN;
DR   Q924X2, CPT1B_MOUSE;  Q8HY46, CPT1B_PIG  ;  Q63704, CPT1B_RAT  ;
DR   Q8TCG5, CPT1C_HUMAN;  Q8BGD5, CPT1C_MOUSE;  Q2KJB7, CPT2_BOVIN ;
DR   Q5U3U3, CPT2_DANRE ;  P23786, CPT2_HUMAN ;  Q60HG9, CPT2_MACFA ;
DR   P52825, CPT2_MOUSE ;  P18886, CPT2_RAT   ;  Q7ZXE1, CPT2_XENLA ;
DR   Q6P4X5, CPT2_XENTR ;
//
ID   2.3.1.22
DE   2-acylglycerol O-acyltransferase.
AN   Acylglycerol palmitoyltransferase.
AN   Monoglyceride acyltransferase.
CA   Acyl-CoA + 2-acylglycerol = CoA + diacylglycerol.
CC   -!- Various 2-acylglycerols can act as acceptor.
CC   -!- Palmitoyl-CoA and other long-chain acyl-CoAs can act as donors.
CC   -!- The sn-1 position and the sn-3 position are both acylated, at about
CC       the same rate.
DR   Q2KHS5, MOG2A_XENLA;  Q5M7F4, MOG2B_XENLA;  Q70VZ7, MOGT1_BOVIN;
DR   Q96PD6, MOGT1_HUMAN;  Q91ZV4, MOGT1_MOUSE;  Q3KPP4, MOGT1_XENLA;
DR   Q28C88, MOGT1_XENTR;  Q3SYC2, MOGT2_HUMAN;  Q80W94, MOGT2_MOUSE;
DR   Q5M8H5, MOGT2_XENTR;  Q86VF5, MOGT3_HUMAN;
//
ID   2.3.1.23
DE   1-acylglycerophosphocholine O-acyltransferase.
AN   Lysolecithin acyltransferase.
CA   Acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine = CoA + 1,2-diacyl-
CA   sn-glycero-3-phosphocholine.
CC   -!- Acts preferentially with unsaturated acyl-CoA derivatives.
CC   -!- 1-acyl-sn-glycero-3-phosphoinositol can also act as acceptor.
DR   O42916, ALE1_SCHPO ;  Q08548, ALE1_YEAST ;  Q8R3I2, MBOA2_MOUSE;
DR   Q3SZL3, MBOA5_BOVIN;  Q6P1A2, MBOA5_HUMAN;  Q91V01, MBOA5_MOUSE;
DR   Q5FVN0, MBOA5_RAT  ;  Q1LWG4, PCAT1_DANRE;  Q0KHU5, PCAT1_DROME;
DR   Q8NF37, PCAT1_HUMAN;  Q3TFD2, PCAT1_MOUSE;  Q1HAQ0, PCAT1_RAT  ;
DR   Q502J0, PCAT2_DANRE;  Q7L5N7, PCAT2_HUMAN;  Q8BYI6, PCAT2_MOUSE;
DR   P0C1Q3, PCAT2_RAT  ;  Q54DX7, TAZ1_DICDI ;  Q06510, TAZ1_YEAST ;
//
ID   2.3.1.24
DE   Sphingosine N-acyltransferase.
CA   Acyl-CoA + sphingosine = CoA + N-acylsphingosine.
CC   -!- Acts on sphingosine or its 2-epimer.
DR   O59735, LAC1_SCHPO ;  A6ZZV7, LAC1_YEAS7 ;  P28496, LAC1_YEAST ;
DR   P78970, LAG1_SCHPO ;  A6ZSP9, LAG1_YEAS7 ;  P38703, LAG1_YEAST ;
//
ID   2.3.1.25
DE   Plasmalogen synthase.
CA   Acyl-CoA + 1-O-alk-1-enyl-glycero-3-phosphocholine = CoA +
CA   plasmenylcholine.
//
ID   2.3.1.26
DE   Sterol O-acyltransferase.
AN   Cholesterol acyltransferase.
AN   Sterol-ester synthase.
CA   Acyl-CoA + cholesterol = CoA + cholesterol ester.
CC   -!- The animal enzyme is highly specific for transfer of acyl groups with
CC       a single cis double bond 9 carbon atoms distant from the carboxy
CC       group.
DR   Q876L3, ARE1_SACBA ;  P25628, ARE1_YEAST ;  P84285, ARE2_CANAL ;
DR   Q876L2, ARE2_SACBA ;  P53629, ARE2_YEAST ;  Q10269, AREH1_SCHPO;
DR   Q9UU82, AREH2_SCHPO;  O77760, SOAT1_CHLAE;  Q60457, SOAT1_CRIGR;
DR   P35610, SOAT1_HUMAN;  O77761, SOAT1_MACFA;  Q61263, SOAT1_MOUSE;
DR   O70536, SOAT1_RAT  ;  O77759, SOAT2_CHLAE;  O75908, SOAT2_HUMAN;
DR   O88908, SOAT2_MOUSE;  Q7TQM4, SOAT2_RAT  ;
//
ID   2.3.1.27
DE   Cortisol O-acetyltransferase.
CA   Acetyl-CoA + cortisol = CoA + cortisol 21-acetate.
//
ID   2.3.1.28
DE   Chloramphenicol O-acetyltransferase.
CA   Acetyl-CoA + chloramphenicol = CoA + chloramphenicol 3-acetate.
CC   -!- Chloramphenicol is an antibiotic.
PR   PROSITE; PDOC00093;
PR   PROSITE; PDOC00094;
DR   P26825, CAT1_CLOPE ;  P00485, CAT1_STAAU ;  P26826, CAT2_CLOPE ;
DR   P22615, CAT2_ECOLX ;  P22616, CAT2_HAEIF ;  P00486, CAT2_STAAU ;
DR   P00484, CAT3_ECOLX ;  P06135, CAT3_STAAU ;  P23364, CAT4_AGRT5 ;
DR   P26838, CAT4_ECOLX ;  P50868, CAT4_ENTAE ;  P50869, CAT4_MORMO ;
DR   P26841, CAT4_PSEAE ;  P36882, CAT4_STAAU ;  P36883, CAT5_STAAU ;
DR   P62578, CAT_ACIAN  ;  P62579, CAT_ACIBA  ;  P00487, CAT_BACPU  ;
DR   P22782, CAT_CAMCO  ;  Q02736, CAT_CLOBU  ;  P11504, CAT_CLODI  ;
DR   P62577, CAT_ECOLX  ;  P58777, CAT_KLESP  ;  P07641, CAT_PROMI  ;
DR   P62580, CAT_SALTI  ;  P25309, CAT_STAIN  ;  P20074, CAT_STRAC  ;
DR   Q03058, CAT_STRAG  ;  P49417, CAT_VIBAN  ;
//
ID   2.3.1.29
DE   Glycine C-acetyltransferase.
AN   2-amino-3-ketobutyrate coenzyme A ligase.
CA   Acetyl-CoA + glycine = CoA + 2-amino-3-oxobutanoate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Acts in concert with EC 1.1.1.103 in the degradation of threonine to
CC       form glycine.
CC   -!- This threonine degradation pathway is common to prokaryotic and
CC       eukaryotic cells and the two enzymes involved form a complex.
PR   PROSITE; PDOC00518;
DR   A6TU88, BIKB_ALKMQ ;  A8MEX7, BIKB_ALKOO ;  A7Z4X1, BIKB_BACA2 ;
DR   A8FDG9, BIKB_BACP2 ;  O31777, BIKB_BACSU ;  B2IH50, BIKB_BEII9 ;
DR   B3QLR6, BIKB_CHLP8 ;  B5Y9Z4, BIKB_COPPD ;  P0AB78, BIKB_ECO57 ;
DR   B1YMC6, BIKB_EXIS2 ;  A7HMM1, BIKB_FERNB ;  A9HJ57, BIKB_GLUDA ;
DR   Q0BUV6, BIKB_GRABC ;  Q7VL09, BIKB_HAEDU ;  Q9ZLN3, BIKB_HELPJ ;
DR   O25320, BIKB_HELPY ;  B7L0L2, BIKB_METC4 ;  A9W106, BIKB_METEP ;
DR   B8IBW2, BIKB_METNO ;  B1Z7Y8, BIKB_METPB ;  B1LYP9, BIKB_METRJ ;
DR   B0UKC8, BIKB_METS4 ;  B8ERL9, BIKB_METSB ;  A0QHJ9, BIKB_MYCA1 ;
DR   P0A4X5, BIKB_MYCBO ;  A1KJ00, BIKB_MYCBP ;  A4T9L3, BIKB_MYCGI ;
DR   B8ZR84, BIKB_MYCLB ;  P45487, BIKB_MYCLE ;  B2HQ90, BIKB_MYCMM ;
DR   Q740R7, BIKB_MYCPA ;  A0QX65, BIKB_MYCS2 ;  A3Q146, BIKB_MYCSJ ;
DR   A1UHM3, BIKB_MYCSK ;  Q1B7F0, BIKB_MYCSS ;  A5U2S6, BIKB_MYCTA ;
DR   A5WMQ5, BIKB_MYCTF ;  P0A4X4, BIKB_MYCTU ;  A0PP02, BIKB_MYCUA ;
DR   A1T8U6, BIKB_MYCVP ;  A9BGL0, BIKB_PETMO ;  P37419, BIKB_SALTY ;
DR   P0AB79, BIKB_SHIFL ;  Q67N86, BIKB_SYMTH ;  B7ID58, BIKB_THEAB ;
DR   A6LMP4, BIKB_THEM4 ;  B0KC20, BIKB_THEP3 ;  B0K590, BIKB_THEPX ;
DR   Q5SHZ8, BIKB_THET8 ;  Q73KM3, BIKB_TREDE ;  Q0P5L8, KBL_BOVIN  ;
DR   P0AB77, KBL_ECOLI  ;  O75600, KBL_HUMAN  ;  O88986, KBL_MOUSE  ;
//
ID   2.3.1.30
DE   Serine O-acetyltransferase.
CA   Acetyl-CoA + L-serine = CoA + O-acetyl-L-serine.
PR   PROSITE; PDOC00094;
DR   Q65PC9, CYSE_BACLD ;  A8F961, CYSE_BACP2 ;  Q06750, CYSE_BACSU ;
DR   P57162, CYSE_BUCAI ;  P32003, CYSE_BUCAP ;  Q89B11, CYSE_BUCBP ;
DR   P0A9D6, CYSE_ECO57 ;  P0A9D5, CYSE_ECOL6 ;  P0A9D4, CYSE_ECOLI ;
DR   P43886, CYSE_HAEIN ;  Q9ZK14, CYSE_HELPJ ;  P71405, CYSE_HELPY ;
DR   P95231, CYSE_MYCTU ;  P29847, CYSE_SALTY ;  P0A9D7, CYSE_SHIFL ;
DR   Q5HIE6, CYSE_STAAC ;  P67764, CYSE_STAAM ;  P67765, CYSE_STAAN ;
DR   Q6GJE0, CYSE_STAAR ;  Q6GBV9, CYSE_STAAS ;  P67766, CYSE_STAAW ;
DR   Q5HRM4, CYSE_STAEQ ;  Q8CTU2, CYSE_STAES ;  P77985, CYSE_STAXY ;
DR   Q56002, CYSE_SYNE7 ;  P74089, CYSE_SYNY3 ;  P23145, NIFP_AZOCH ;
DR   Q42588, SAT1_ARATH ;  Q8W0E4, SAT1_ORYSJ ;  Q8S895, SAT2_ARATH ;
DR   Q10S58, SAT2_ORYSJ ;  Q39218, SAT3_ARATH ;  Q0DUI1, SAT3_ORYSJ ;
DR   Q8W2B8, SAT4_ARATH ;  Q10QH1, SAT4_ORYSJ ;  Q42538, SAT5_ARATH ;
DR   Q0DGG8, SAT5_ORYSJ ;  P85931, SAT_PSEMZ  ;  Q9US33, SAT_SCHPO  ;
DR   Q59967, SRPH_SYNE7 ;
//
ID   2.3.1.31
DE   Homoserine O-acetyltransferase.
AN   Homoserine O-trans-acetylase.
AN   Homoserine transacetylase.
CA   Acetyl-CoA + L-homoserine = CoA + O-acetyl-L-homoserine.
DR   P12917, MET2_ASCIM ;  Q9Y875, MET2_EMENI ;  Q06736, MET2_SACPS ;
DR   O60062, MET2_SCHPO ;  P08465, MET2_YEAST ;  Q6FEQ3, METX_ACIAD ;
DR   B7H098, METX_ACIB3 ;  B7I4X4, METX_ACIB5 ;  B2I3B6, METX_ACIBC ;
DR   B0VL51, METX_ACIBS ;  A3M1Y2, METX_ACIBT ;  B0V4S0, METX_ACIBY ;
DR   A5FVN0, METX_ACICJ ;  B7J437, METX_ACIF2 ;  B5ELV1, METX_ACIF5 ;
DR   Q0ABU4, METX_ALHEH ;  Q3M5Q6, METX_ANAVT ;  Q5P4R1, METX_AROAE ;
DR   A1KCN1, METX_AZOSB ;  C1DI67, METX_AZOVD ;  Q2KU63, METX_BORA1 ;
DR   Q7WES8, METX_BORBR ;  Q7W3F8, METX_BORPA ;  A9I0E6, METX_BORPD ;
DR   Q7W0P6, METX_BORPE ;  Q89UL7, METX_BRAJA ;  B1YPU9, METX_BURA4 ;
DR   Q1BSM1, METX_BURCA ;  B1K0G8, METX_BURCC ;  A0KBH0, METX_BURCH ;
DR   B4E7Y5, METX_BURCJ ;  Q0BAW3, METX_BURCM ;  A9AC42, METX_BURM1 ;
DR   A3MRS1, METX_BURM7 ;  A2S877, METX_BURM9 ;  Q62F07, METX_BURMA ;
DR   A1V7J8, METX_BURMS ;  A3NQ54, METX_BURP0 ;  Q3JXB2, METX_BURP1 ;
DR   A3N4G4, METX_BURP6 ;  B2JJW9, METX_BURP8 ;  B2T1N1, METX_BURPP ;
DR   Q63YJ0, METX_BURPS ;  Q39BX2, METX_BURS3 ;  Q2T284, METX_BURTA ;
DR   A4JIS1, METX_BURVG ;  Q146X7, METX_BURXL ;  Q3AAW2, METX_CARHZ ;
DR   B8GZZ0, METX_CAUCN ;  Q9AAS1, METX_CAUCR ;  B3PFK3, METX_CELJU ;
DR   Q3ARA7, METX_CHLCH ;  B3QM89, METX_CHLP8 ;  B3QZ51, METX_CHLT3 ;
DR   Q8KES7, METX_CHLTE ;  Q7NZY3, METX_CHRVO ;  A5CQM6, METX_CLAM3 ;
DR   Q6NIZ3, METX_CORDI ;  Q8FRT0, METX_COREF ;  O68640, METX_CORGL ;
DR   Q4JTI5, METX_CORJK ;  B1VF43, METX_CORU7 ;  Q0KF58, METX_CUPNH ;
DR   Q476W5, METX_CUPPJ ;  B2AGC8, METX_CUPTR ;  Q47JU2, METX_DECAR ;
DR   Q9RVZ8, METX_DEIRA ;  Q6ANV2, METX_DESPS ;  B5EAS1, METX_GEOBB ;
DR   B3E278, METX_GEOLS ;  Q39RX3, METX_GEOMG ;  B9M4M5, METX_GEOSF ;
DR   Q74AC8, METX_GEOSL ;  A5GC94, METX_GEOUR ;  Q5FUF4, METX_GLUOX ;
DR   Q0BVW2, METX_GRABC ;  Q4QJY8, METX_HAEI8 ;  P45131, METX_HAEIN ;
DR   Q2S8M0, METX_HAHCH ;  A1WVL3, METX_HALHL ;  Q5UY71, METX_HALMA ;
DR   P57715, METX_HALSA ;  A4G1K0, METX_HERAR ;  A6SUC4, METX_JANMA ;
DR   C1D4Z8, METX_LARHH ;  Q6ADB9, METX_LEIXX ;  B0SHJ0, METX_LEPBA ;
DR   Q04RK8, METX_LEPBJ ;  Q052B3, METX_LEPBL ;  B0SQZ8, METX_LEPBP ;
DR   B1XW69, METX_LEPCP ;  Q72R95, METX_LEPIC ;  Q8F4I0, METX_LEPIN ;
DR   P94891, METX_LEPME ;  Q92E58, METX_LISIN ;  Q722V6, METX_LISMF ;
DR   Q8Y9D6, METX_LISMO ;  A0LCI7, METX_MAGSM ;  Q65U29, METX_MANSM ;
DR   A1TY14, METX_MARAV ;  A6W3E8, METX_MARMS ;  A2SLU8, METX_METPP ;
DR   O27848, METX_METTH ;  Q2RIW8, METX_MOOTA ;  A0QKL5, METX_MYCA1 ;
DR   P0A5J9, METX_MYCBO ;  A1KP32, METX_MYCBP ;  C1AHF8, METX_MYCBT ;
DR   B8ZUV9, METX_MYCLB ;  O32874, METX_MYCLE ;  B2HDS6, METX_MYCMM ;
DR   Q73UB0, METX_MYCPA ;  A0QSZ0, METX_MYCS2 ;  A1UC78, METX_MYCSK ;
DR   Q1BCR5, METX_MYCSS ;  A5U815, METX_MYCTA ;  P0A5J8, METX_MYCTU ;
DR   A0PNQ1, METX_MYCUA ;  Q3IUE8, METX_NATPD ;  Q5F858, METX_NEIG1 ;
DR   Q9JUT9, METX_NEIMA ;  Q9JZQ5, METX_NEIMB ;  Q0AIM3, METX_NITEC ;
DR   Q81ZZ5, METX_NITEU ;  Q1QQD3, METX_NITHX ;  Q2YCJ2, METX_NITMU ;
DR   Q3SV39, METX_NITWN ;  Q5Z1C4, METX_NOCFA ;  A1SMU5, METX_NOCSJ ;
DR   B2IY96, METX_NOSP7 ;  P57884, METX_PASMU ;  Q3A7G2, METX_PELCD ;
DR   Q3B5A5, METX_PELLD ;  A1AUS2, METX_PELPD ;  Q4FP51, METX_PELUB ;
DR   Q48PA1, METX_PSE14 ;  A6UYJ9, METX_PSEA7 ;  B7V3X6, METX_PSEA8 ;
DR   Q02U23, METX_PSEAB ;  P57714, METX_PSEAE ;  Q1IGC6, METX_PSEE4 ;
DR   Q4K4D3, METX_PSEF5 ;  C3K3L0, METX_PSEFS ;  A4XZY6, METX_PSEMY ;
DR   A5WAD0, METX_PSEP1 ;  Q3K594, METX_PSEPF ;  B0KN51, METX_PSEPG ;
DR   Q88CT3, METX_PSEPK ;  B1J2H5, METX_PSEPW ;  Q87V90, METX_PSESM ;
DR   Q4ZZ78, METX_PSEU2 ;  A4VRJ2, METX_PSEU5 ;  Q4FUR4, METX_PSYA2 ;
DR   Q1LS47, METX_RALME ;  B2U7Y8, METX_RALPJ ;  Q8Y3F3, METX_RALSO ;
DR   Q98G09, METX_RHILO ;  Q2IS70, METX_RHOP2 ;  Q6N1G8, METX_RHOPA ;
DR   Q20YI1, METX_RHOPB ;  Q2RP84, METX_RHORT ;  Q21EI0, METX_SACD2 ;
DR   B2FMC1, METX_STRMK ;  Q67NS3, METX_SYMTH ;  C5BLJ8, METX_TERTT ;
DR   Q47L17, METX_THEFY ;  Q9RA51, METX_THET2 ;  Q5SK89, METX_THET8 ;
DR   Q31EJ2, METX_THICR ;  Q8PK44, METX_XANAC ;  Q3BSK1, METX_XANC5 ;
DR   Q4UVH1, METX_XANC8 ;  B0RS70, METX_XANCB ;  Q8P8L2, METX_XANCP ;
DR   Q2P3Z2, METX_XANOM ;  Q5H124, METX_XANOR ;  B2I700, METX_XYLF2 ;
DR   Q9PAN0, METX_XYLFA ;  B0U3V7, METX_XYLFM ;  Q87BG9, METX_XYLFT ;
DR   Q5NR05, METX_ZYMMO ;
//
ID   2.3.1.32
DE   Lysine N-acetyltransferase.
AN   LAT.
AN   Lysine acetyltransferase.
AN   Lysine N(6)-acetyltransferase.
CA   Acetyl phosphate + L-lysine = phosphate + N(6)-acetyl-L-lysine.
DR   P41929, LYC1_YARLI ;
//
ID   2.3.1.33
DE   Histidine N-acetyltransferase.
CA   Acetyl-CoA + L-histidine = CoA + N-acetyl-L-histidine.
//
ID   2.3.1.34
DE   D-tryptophan N-acetyltransferase.
CA   Acetyl-CoA + D-tryptophan = CoA + N-acetyl-D-tryptophan.
//
ID   2.3.1.35
DE   Glutamate N-acetyltransferase.
AN   Acetylglutamate synthetase.
AN   Acetylglutamate-acetylornithine transacetylase.
AN   Acetylglutamic synthetase.
AN   Acetylglutamic-acetylornithine transacetylase.
AN   Acetylornithinase.
AN   Acetylornithine glutamate acetyltransferase.
AN   Glutamate acetyltransferase.
AN   N-acetyl-L-glutamate synthetase.
AN   N-acetylglutamate synthase.
AN   N-acetylglutamate synthetase.
AN   Ornithine acetyltransferase.
AN   Ornithine transacetylase.
CA   N(2)-acetyl-L-ornithine + L-glutamate = L-ornithine + N-acetyl-L-
CA   glutamate.
CC   -!- Also has some hydrolytic activity on acetyl-L-ornithine, but the rate
CC       is 1% of that of transferase activity.
DR   A6S146, ARGJ1_BOTFB;  Q97GH6, ARGJ1_CLOAB;  Q8YVA8, ARGJ1_NOSS1;
DR   A7E5P6, ARGJ1_SCLS1;  A6S9T6, ARGJ2_BOTFB;  Q97ET6, ARGJ2_CLOAB;
DR   Q8YPF9, ARGJ2_NOSS1;  A7EDG9, ARGJ2_SCLS1;  Q6FED8, ARGJ_ACIAD ;
DR   Q8UA56, ARGJ_AGRT5 ;  C0NE02, ARGJ_AJECG ;  C6HSY8, ARGJ_AJECH ;
DR   A6R040, ARGJ_AJECN ;  C5GXZ4, ARGJ_AJEDR ;  C5K110, ARGJ_AJEDS ;
DR   O67100, ARGJ_AQUAE ;  Q9ZUR7, ARGJ_ARATH ;  O29118, ARGJ_ARCFU ;
DR   Q5P706, ARGJ_AROAE ;  C5FHS6, ARGJ_ARTOC ;  Q759Y5, ARGJ_ASHGO ;
DR   A1CAP4, ARGJ_ASPCL ;  B0Y3W4, ARGJ_ASPFC ;  B8NEJ3, ARGJ_ASPFN ;
DR   Q4WUE0, ARGJ_ASPFU ;  A2QGS5, ARGJ_ASPNC ;  Q2U7R8, ARGJ_ASPOR ;
DR   Q0CDB9, ARGJ_ASPTN ;  Q9ZJ14, ARGJ_BACAM ;  Q81M96, ARGJ_BACAN ;
DR   P62057, ARGJ_BACC1 ;  Q818W0, ARGJ_BACCR ;  Q635F1, ARGJ_BACCZ ;
DR   Q9K8V3, ARGJ_BACHD ;  Q6HE29, ARGJ_BACHK ;  Q65LE9, ARGJ_BACLD ;
DR   Q5WEW8, ARGJ_BACSK ;  P36843, ARGJ_BACSU ;  Q6G5T6, ARGJ_BARHE ;
DR   Q6G0Q6, ARGJ_BARQU ;  Q8G5F0, ARGJ_BIFLO ;  Q7WF54, ARGJ_BORBR ;
DR   Q7W3S6, ARGJ_BORPA ;  Q7VSW3, ARGJ_BORPE ;  P59610, ARGJ_BRAJA ;
DR   Q57AV8, ARGJ_BRUAB ;  Q8YJF9, ARGJ_BRUME ;  Q8FYE2, ARGJ_BRUSU ;
DR   Q62GT9, ARGJ_BURMA ;  Q3JNE9, ARGJ_BURP1 ;  Q63QK7, ARGJ_BURPS ;
DR   Q39JW0, ARGJ_BURS3 ;  Q5AH38, ARGJ_CANAL ;  C4YTS0, ARGJ_CANAW ;
DR   B9WK98, ARGJ_CANDC ;  Q6FU44, ARGJ_CANGA ;  C5MG55, ARGJ_CANTT ;
DR   Q3A9W1, ARGJ_CARHZ ;  Q9A3Y4, ARGJ_CAUCR ;  Q2HAX7, ARGJ_CHAGB ;
DR   Q3ASI6, ARGJ_CHLCH ;  P59611, ARGJ_CHLTE ;  Q7P0T8, ARGJ_CHRVO ;
DR   Q3C251, ARGJ_CITLA ;  C4Y584, ARGJ_CLAL4 ;  C5P7K2, ARGJ_COCP7 ;
DR   Q486G0, ARGJ_COLP3 ;  A8NAN2, ARGJ_COPC7 ;  P62058, ARGJ_CORCT ;
DR   P62059, ARGJ_CORDI ;  Q8FTN4, ARGJ_COREF ;  Q59280, ARGJ_CORGL ;
DR   Q4JW03, ARGJ_CORJK ;  P0CM21, ARGJ_CRYNB ;  P0CM20, ARGJ_CRYNJ ;
DR   Q46X04, ARGJ_CUPPJ ;  Q6BKT4, ARGJ_DEBHA ;  Q47AB5, ARGJ_DECAR ;
DR   Q3Z731, ARGJ_DEHE1 ;  Q3ZYG4, ARGJ_DEHSC ;  Q9RTQ2, ARGJ_DEIRA ;
DR   Q6AJL0, ARGJ_DESPS ;  P62060, ARGJ_DESVH ;  Q54DY1, ARGJ_DICDI ;
DR   Q5AVF8, ARGJ_EMENI ;  Q5L1V4, ARGJ_GEOKA ;  Q07908, ARGJ_GEOSE ;
DR   P62061, ARGJ_GEOSL ;  Q7NE46, ARGJ_GLOVI ;  Q5FQD0, ARGJ_GLUOX ;
DR   Q93EJ3, ARGJ_HELHP ;  Q6CII9, ARGJ_KLULA ;  B0D316, ARGJ_LACBS ;
DR   Q9CHD4, ARGJ_LACLA ;  O08319, ARGJ_LACPL ;  C5DCN3, ARGJ_LACTC ;
DR   P62062, ARGJ_LEPIC ;  Q8EYV8, ARGJ_LEPIN ;  Q92BB8, ARGJ_LISIN ;
DR   Q71Z77, ARGJ_LISMF ;  Q8Y6U2, ARGJ_LISMO ;  A5E7B9, ARGJ_LODEL ;
DR   A4R5F6, ARGJ_MAGO7 ;  C0PF72, ARGJ_MAIZE ;  A8Q9M0, ARGJ_MALGO ;
DR   Q8TK55, ARGJ_METAC ;  Q607S6, ARGJ_METCA ;  Q57645, ARGJ_METJA ;
DR   Q8TX15, ARGJ_METKA ;  A4FXT1, ARGJ_METM5 ;  A9AB46, ARGJ_METM6 ;
DR   A6VFI9, ARGJ_METM7 ;  Q8PZL8, ARGJ_METMA ;  P62065, ARGJ_METMP ;
DR   O26284, ARGJ_METTH ;  A6UN66, ARGJ_METVS ;  P63572, ARGJ_MYCBO ;
DR   Q9CC14, ARGJ_MYCLE ;  P62063, ARGJ_MYCPA ;  P63571, ARGJ_MYCTU ;
DR   C7YUB3, ARGJ_NECH7 ;  Q5F7I3, ARGJ_NEIG1 ;  P38434, ARGJ_NEIGO ;
DR   P63573, ARGJ_NEIMA ;  P63574, ARGJ_NEIMB ;  A1DF20, ARGJ_NEOFI ;
DR   A7UWD5, ARGJ_NEUCR ;  Q82SU1, ARGJ_NITEU ;  Q3J7A0, ARGJ_NITOC ;
DR   Q3SVN6, ARGJ_NITWN ;  Q5YYF8, ARGJ_NOCFA ;  Q8CUN1, ARGJ_OCEIH ;
DR   B8AL33, ARGJ_ORYSI ;  Q10N79, ARGJ_ORYSJ ;  A4S1K1, ARGJ_OSTLU ;
DR   C1H986, ARGJ_PARBA ;  C1GEZ1, ARGJ_PARBD ;  C0SCV8, ARGJ_PARBP ;
DR   Q3A246, ARGJ_PELCD ;  B6HQD4, ARGJ_PENCW ;  B6QFZ6, ARGJ_PENMQ ;
DR   D0N1U4, ARGJ_PHYIN ;  A9SLE5, ARGJ_PHYPA ;  A5DAF0, ARGJ_PICGU ;
DR   C4R3R8, ARGJ_PICPG ;  A3LWC0, ARGJ_PICST ;  B2B4X6, ARGJ_PODAN ;
DR   D3AXF4, ARGJ_POLPA ;  B9NAN0, ARGJ_POPTR ;  B8PH83, ARGJ_POSPM ;
DR   Q7VEF9, ARGJ_PROMA ;  Q7V436, ARGJ_PROMM ;  Q7V3M5, ARGJ_PROMP ;
DR   Q46I07, ARGJ_PROMT ;  Q48EG7, ARGJ_PSE14 ;  Q9HW04, ARGJ_PSEAE ;
DR   Q4K7C2, ARGJ_PSEF5 ;  Q3K7U0, ARGJ_PSEPF ;  P59612, ARGJ_PSEPK ;
DR   Q87WZ4, ARGJ_PSESM ;  Q4ZNZ9, ARGJ_PSEU2 ;  Q4FSF9, ARGJ_PSYA2 ;
DR   B2VVA8, ARGJ_PYRTR ;  Q8XVJ7, ARGJ_RALSO ;  Q98G72, ARGJ_RHILO ;
DR   Q92MJ1, ARGJ_RHIME ;  Q7UUJ7, ARGJ_RHOBA ;  P96426, ARGJ_RHOFA ;
DR   P62064, ARGJ_RHOPA ;  B9SZB6, ARGJ_RICCO ;  B6JYD2, ARGJ_SCHJY ;
DR   O94346, ARGJ_SCHPO ;  Q5LWL6, ARGJ_SILPO ;  C5WPC2, ARGJ_SORBI ;
DR   D1ZHR9, ARGJ_SORMK ;  Q5HJJ0, ARGJ_STAAC ;  P63575, ARGJ_STAAM ;
DR   P63576, ARGJ_STAAN ;  Q6GKC3, ARGJ_STAAR ;  Q6GCU3, ARGJ_STAAS ;
DR   Q8NYM7, ARGJ_STAAW ;  Q5HP22, ARGJ_STAEQ ;  Q8CSF9, ARGJ_STAES ;
DR   Q4A0N0, ARGJ_STAS1 ;  Q828A5, ARGJ_STRAW ;  Q9LCS7, ARGJ_STRCL ;
DR   Q8CK24, ARGJ_STRCO ;  Q8DV45, ARGJ_STRMU ;  Q5M122, ARGJ_STRT1 ;
DR   Q5M5L0, ARGJ_STRT2 ;  Q67KC5, ARGJ_SYMTH ;  Q5MZY1, ARGJ_SYNP6 ;
DR   Q7U3S6, ARGJ_SYNPX ;  P74122, ARGJ_SYNY3 ;  B8M9V7, ARGJ_TALSN ;
DR   B8BVB6, ARGJ_THAPS ;  Q8DHN4, ARGJ_THEEB ;  Q47N80, ARGJ_THEFY ;
DR   Q9X2A3, ARGJ_THEMA ;  Q9Z4S1, ARGJ_THENN ;  P96137, ARGJ_THET2 ;
DR   Q5SJ18, ARGJ_THET8 ;  Q8R7B9, ARGJ_THETN ;  Q3SMQ9, ARGJ_THIDA ;
DR   C4JMY4, ARGJ_UNCRE ;  P0CH65, ARGJ_USTMA ;  A7TPS8, ARGJ_VANPO ;
DR   C9S923, ARGJ_VERA1 ;  A5AEC8, ARGJ_VITVI ;  Q7MAC9, ARGJ_WOLSU ;
DR   Q6C627, ARGJ_YARLI ;  B3LLV5, ARGJ_YEAS1 ;  C7GL62, ARGJ_YEAS2 ;
DR   B5VPI9, ARGJ_YEAS6 ;  A6ZMC1, ARGJ_YEAS7 ;  C8ZER4, ARGJ_YEAS8 ;
DR   Q04728, ARGJ_YEAST ;  C5E3Y4, ARGJ_ZYGRC ;  Q5NP13, ARGJ_ZYMMO ;
DR   P62252, GNAT1_STRCL;  Q53940, GNAT2_STRCL;
//
ID   2.3.1.36
DE   D-amino-acid N-acetyltransferase.
CA   Acetyl-CoA + a D-amino acid = CoA + an N-acetyl-D-amino acid.
//
ID   2.3.1.37
DE   5-aminolevulinate synthase.
AN   5-aminolevulinic acid synthase.
AN   ALAS.
AN   Delta-ALA synthetase.
AN   Delta-aminolevulinate synthase.
CA   Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO(2).
CF   Pyridoxal 5'-phosphate.
PR   PROSITE; PDOC00518;
DR   Q3ZC31, HEM0_BOVIN ;  P18080, HEM0_CHICK ;  Q9YHT4, HEM0_DANRE ;
DR   Q9XT75, HEM0_DELLE ;  P22557, HEM0_HUMAN ;  P08680, HEM0_MOUSE ;
DR   P43090, HEM0_OPSTA ;  Q5R557, HEM0_PONAB ;  Q63147, HEM0_RAT   ;
DR   Q06965, HEM0_RHOS4 ;  Q92403, HEM1_AGABI ;  Q75DX7, HEM1_ASHGO ;
DR   A6QLI6, HEM1_BOVIN ;  P08262, HEM1_BRAJA ;  O94069, HEM1_CANAL ;
DR   Q6FXE3, HEM1_CANGA ;  P07997, HEM1_CHICK ;  Q6BX71, HEM1_DEBHA ;
DR   Q9XS79, HEM1_DELLE ;  P38092, HEM1_EMENI ;  P13196, HEM1_HUMAN ;
DR   P78698, HEM1_KLULA ;  Q8VC19, HEM1_MOUSE ;  Q7RVY5, HEM1_NEUCR ;
DR   P43091, HEM1_OPSTA ;  P43089, HEM1_PARDP ;  Q5R9R9, HEM1_PONAB ;
DR   P13195, HEM1_RAT   ;  P08080, HEM1_RHIME ;  P26505, HEM1_RHIRD ;
DR   P18079, HEM1_RHOCB ;  Q04512, HEM1_RHOS4 ;  Q1RIV2, HEM1_RICBR ;
DR   Q92G23, HEM1_RICCN ;  Q4UJV4, HEM1_RICFE ;  Q9ZCB8, HEM1_RICPR ;
DR   Q68VS3, HEM1_RICTY ;  O14092, HEM1_SCHPO ;  Q6CCW0, HEM1_YARLI ;
DR   P09950, HEM1_YEAST ;
//
ID   2.3.1.38
DE   [Acyl-carrier-protein] S-acetyltransferase.
AN   ACAT.
AN   Acetyl coenzyme A-acyl-carrier-protein transacylase.
AN   ACP acetyltransferase.
AN   Acyl-carrier-protein acetyltransferase.
CA   Acetyl-CoA + [acyl-carrier-protein] = CoA + acetyl-[acyl-carrier-
CA   protein].
CC   -!- Essential, along with EC 2.3.1.39, for the initiation of fatty-acid
CC       biosynthesis in bacteria.
CC   -!- The substrate acetyl-CoA protects the enzyme against inhibition by
CC       N-ethylmaleimide or iodoacetamide.
CC   -!- This is one of the activities associated with EC 2.3.1.180.
DR   P34731, FAS1_CANAL ;  Q9UUG0, FAS1_SCHPO ;  P34229, FAS1_YARLI ;
DR   P07149, FAS1_YEAST ;  Q71SP7, FAS_BOVIN  ;  P12276, FAS_CHICK  ;
DR   P49327, FAS_HUMAN  ;  P19096, FAS_MOUSE  ;  P12785, FAS_RAT    ;
DR   Q92215, TOXC_COCCA ;
//
ID   2.3.1.39
DE   [Acyl-carrier-protein] S-malonyltransferase.
AN   Acyl carrier protein malonyltransferase.
AN   Malonyl coenzyme A-acyl carrier protein transacylase.
AN   Malonyl transacylase.
AN   Malonyl transferase.
AN   Malonyl-CoA-acyl carrier protein transacylase.
AN   Malonyl-CoA/dephospho-CoA acyltransferase.
AN   MCAT.
CA   Malonyl-CoA + [acyl-carrier-protein] = CoA + malonyl-[acyl-carrier-
CA   protein].
CC   -!- Essential, along with EC 2.3.1.38, for the initiation of fatty-acid
CC       biosynthesis in bacteria.
CC   -!- Also provides the malonyl groups for polyketide biosynthesis.
CC   -!- The product of the reaction, malonyl-ACP, is an elongation substrate
CC       in fatty-acid biosynthesis.
CC   -!- In Mycobacterium tuberculosis, holo-ACP (the product of EC 2.7.8.7)
CC       is the preferred substrate.
CC   -!- This enzyme also forms part of the multienzyme complexes EC 4.1.1.88
CC       and EC 4.1.1.89.
CC   -!- Malonylation of ACP is immediately followed by decarboxylation within
CC       the malonate-decarboxylase complex to yield acetyl-ACP,
CC       the catalytically active species of the decarboxylase.
CC   -!- In the enzyme from Klebsiella pneumoniae, methylmalonyl-CoA can also
CC       act as a substrate but acetyl-CoA cannot whereas the enzyme from
CC       Pseudomonas putida can use both as substrates.
CC   -!- The ACP subunit found in fatty-acid biosynthesis contains a
CC       pantetheine-4'-phosphate prosthetic group; that from malonate
CC       decarboxylase also contains pantetheine-4'-phosphate but in the form
CC       of a 2'-(5-triphosphoribosyl)-3'-dephospho-CoA prosthetic group.
DR   A7Z4X8, BAEC_BACA2 ;  A7Z4Y0, BAEE_BACA2 ;  P71019, FABD_BACSU ;
DR   Q8K9J6, FABD_BUCAP ;  Q89AH0, FABD_BUCBP ;  Q8T3L6, FABD_DROME ;
DR   Q8X8I7, FABD_ECO57 ;  P0AAJ0, FABD_ECOL6 ;  P0AAI9, FABD_ECOLI ;
DR   P43712, FABD_HAEIN ;  Q8IVS2, FABD_HUMAN ;  Q8R3F5, FABD_MOUSE ;
DR   P63459, FABD_MYCBO ;  A0R0B2, FABD_MYCS2 ;  P63458, FABD_MYCTU ;
DR   O85140, FABD_SALTY ;  O13698, FABD_SCHPO ;  Q5HGK3, FABD_STAAC ;
DR   Q99UN8, FABD_STAAM ;  Q7A5Z3, FABD_STAAN ;  Q6GHK5, FABD_STAAR ;
DR   Q6G9Y3, FABD_STAAS ;  Q93QD4, FABD_STAAU ;  Q7A124, FABD_STAAW ;
DR   P73242, FABD_SYNY3 ;  Q12283, FABD_YEAST ;  P34731, FAS1_CANAL ;
DR   Q9UUG0, FAS1_SCHPO ;  P34229, FAS1_YARLI ;  P07149, FAS1_YEAST ;
DR   Q71SP7, FAS_BOVIN  ;  P12276, FAS_CHICK  ;  P49327, FAS_HUMAN  ;
DR   P19096, FAS_MOUSE  ;  P12785, FAS_RAT    ;  Q9R9J2, FENF_BACSU ;
DR   O34825, PKSC_BACSU ;  O34787, PKSE_BACSU ;  Q92215, TOXC_COCCA ;
//
ID   2.3.1.40
DE   Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase.
CA   Acyl-[acyl-carrier-protein] + O-(2-acyl-sn-glycero-3-phospho)ethanolamine
CA   = [acyl-carrier-protein] + O-(1-beta-acyl-2-acyl-sn-glycero-3-
CA   phospho)ethanolamine.
DR   A8AP56, AAS_CITK8  ;  A7ZQU2, AAS_ECO24  ;  B7UHQ4, AAS_ECO27  ;
DR   B7MLI2, AAS_ECO45  ;  B7LF13, AAS_ECO55  ;  Q8X6J8, AAS_ECO57  ;
DR   B5Z4F4, AAS_ECO5E  ;  B7NVY2, AAS_ECO7I  ;  C4ZZY9, AAS_ECOBW  ;
DR   B1XDP2, AAS_ECODH  ;  A8A3X0, AAS_ECOHS  ;  A1AF47, AAS_ECOK1  ;
DR   Q0TDZ6, AAS_ECOL5  ;  Q8FEA6, AAS_ECOL6  ;  B1IU08, AAS_ECOLC  ;
DR   P31119, AAS_ECOLI  ;  B7N768, AAS_ECOLU  ;  B6I6W1, AAS_ECOSE  ;
DR   B1LR34, AAS_ECOSM  ;  Q1R7H5, AAS_ECOUT  ;  A4WE11, AAS_ENT38  ;
DR   A7MR36, AAS_ENTS8  ;  Q6D107, AAS_ERWCT  ;  B2VFS7, AAS_ERWT9  ;
DR   B7LNJ2, AAS_ESCF3  ;  B5XUP2, AAS_KLEP3  ;  A6TDH2, AAS_KLEP7  ;
DR   C6DE43, AAS_PECCP  ;  Q7N7A9, AAS_PHOLL  ;  B5F4V4, AAS_SALA4  ;
DR   Q57KA7, AAS_SALCH  ;  B5FUB9, AAS_SALDC  ;  B5QWU2, AAS_SALEP  ;
DR   B5RDY6, AAS_SALG2  ;  B4TGR5, AAS_SALHS  ;  B4T503, AAS_SALNS  ;
DR   Q5PEN7, AAS_SALPA  ;  A9N3H8, AAS_SALPB  ;  C0PXJ8, AAS_SALPC  ;
DR   B5BFH6, AAS_SALPK  ;  B4TUM9, AAS_SALSV  ;  Q8Z406, AAS_SALTI  ;
DR   Q8ZMA4, AAS_SALTY  ;  B2TYQ5, AAS_SHIB3  ;  Q0T128, AAS_SHIF8  ;
DR   Q83JV7, AAS_SHIFL  ;  Q3YY21, AAS_SHISS  ;  A1JPF0, AAS_YERE8  ;
DR   A7FFD1, AAS_YERP3  ;  Q1CAS8, AAS_YERPA  ;  B2JZ75, AAS_YERPB  ;
DR   Q74RZ6, AAS_YERPE  ;  A9R2S1, AAS_YERPG  ;  A4TLD3, AAS_YERPP  ;
DR   Q667F1, AAS_YERPS  ;  B1JQC1, AAS_YERPY  ;
//
ID   2.3.1.41
DE   Beta-ketoacyl-acyl-carrier-protein synthase I.
AN   3-ketoacyl-acyl carrier protein synthase.
AN   3-oxoacyl-[acyl-carrier-protein] synthase.
AN   Acyl-malonyl acyl carrier protein-condensing enzyme.
AN   Acyl-malonyl(acyl-carrier-protein)-condensing enzyme.
AN   Beta-ketoacyl acyl carrier protein synthase.
AN   Beta-ketoacyl synthetase.
AN   Beta-ketoacyl-[acyl carrier protein] synthase.
AN   Beta-ketoacyl-ACP synthase I.
AN   Beta-ketoacyl-ACP synthetase.
AN   Beta-ketoacyl-acyl carrier protein synthetase.
AN   Beta-ketoacylsynthase.
AN   Condensing enzyme.
AN   Fatty acid condensing enzyme.
AN   KAS I.
CA   Acyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] = 3-oxoacyl-
CA   [acyl-carrier-protein] + CO(2) + [acyl-carrier-protein].
CC   -!- Responsible for the chain-elongation step of dissociated (type II)
CC       fatty-acid biosynthesis, i.e. the addition of two C atoms to the
CC       fatty-acid chain.
CC   -!- Escherichia coli mutants that lack this enzyme are deficient in
CC       unsaturated fatty acids.
CC   -!- Can use fatty acyl thioesters of ACP (C(2) to C(16)) as substrates,
CC       as well as fatty acyl thioesters of Co-A (C(4) to C(16)).
CC   -!- The substrate specificity is very similar to that of EC 2.3.1.179
CC       with the exception that the latter enzyme is far more active with
CC       palmitoleoyl-ACP (C(16)-Delta(9)) as substrate, allowing the organism
CC       to regulate its fatty-acid composition with changes in temperature.
PR   PROSITE; PDOC00529;
DR   P39525, CEM1_YEAST ;  P63455, FAB1_MYCBO ;  Q9CBS7, FAB1_MYCLE ;
DR   P63454, FAB1_MYCTU ;  P63457, FAB2_MYCBO ;  O69473, FAB2_MYCLE ;
DR   P63456, FAB2_MYCTU ;  P57193, FABB_BUCAI ;  Q8KA28, FABB_BUCAP ;
DR   Q89AY4, FABB_BUCBP ;  P0A954, FABB_ECOL6 ;  P0A953, FABB_ECOLI ;
DR   P43710, FABB_HAEIN ;  A1TLD7, FABH_ACIAC ;  Q1IQ32, FABH_ACIBL ;
DR   A5FV65, FABH_ACICJ ;  A1WAX8, FABH_ACISJ ;  A3N232, FABH_ACTP2 ;
DR   A6VQV2, FABH_ACTSZ ;  Q0A8R5, FABH_ALHEH ;  Q5PA98, FABH_ANAMM ;
DR   Q3M9J4, FABH_ANAVT ;  A8ERJ6, FABH_ARCB4 ;  Q5P0D6, FABH_AROAE ;
DR   A1K5Y5, FABH_AZOSB ;  A8FBX4, FABH_BACP2 ;  A6KXK3, FABH_BACV8 ;
DR   Q1LT37, FABH_BAUCH ;  Q492Q4, FABH_BLOPB ;  Q2KUK5, FABH_BORA1 ;
DR   A5EKG5, FABH_BRASB ;  A4YW84, FABH_BRASO ;  Q1BXV4, FABH_BURCA ;
DR   A0K5U6, FABH_BURCH ;  A3MM55, FABH_BURM7 ;  A2S9Y2, FABH_BURM9 ;
DR   Q62LU2, FABH_BURMA ;  A1V6D0, FABH_BURMS ;  A3NXM9, FABH_BURP0 ;
DR   Q3JQ65, FABH_BURP1 ;  A3NBU2, FABH_BURP6 ;  Q63S83, FABH_BURPS ;
DR   Q39I86, FABH_BURS3 ;  Q2SXU7, FABH_BURTA ;  A4JCP8, FABH_BURVG ;
DR   A7ZC01, FABH_CAMC1 ;  A7H054, FABH_CAMC5 ;  A0RMK8, FABH_CAMFF ;
DR   A7I3D6, FABH_CAMHC ;  A8FKB7, FABH_CAMJ8 ;  A7H541, FABH_CAMJD ;
DR   A1VY47, FABH_CAMJJ ;  Q5HWE3, FABH_CAMJR ;  Q3AQ09, FABH_CHLCH ;
DR   A1BJA1, FABH_CHLPD ;  Q3KMC3, FABH_CHLTA ;  A8AHY1, FABH_CITK8 ;
DR   A7FPM6, FABH_CLOB1 ;  A5I7X8, FABH_CLOBH ;  A7GJJ9, FABH_CLOBL ;
DR   Q18B40, FABH_CLOD6 ;  A0PXB6, FABH_CLONN ;  Q0TRH0, FABH_CLOP1 ;
DR   Q0STU9, FABH_CLOPS ;  Q0K8L9, FABH_CUPNH ;  Q46Z05, FABH_CUPPJ ;
DR   Q30YM1, FABH_DESDG ;  Q6AJF8, FABH_DESPS ;  Q72CS6, FABH_DESVH ;
DR   A1VEK1, FABH_DESVV ;  A7ZKJ4, FABH_ECO24 ;  A7ZZ48, FABH_ECOHS ;
DR   A1A9Y5, FABH_ECOK1 ;  Q0TIY3, FABH_ECOL5 ;  Q1RD66, FABH_ECOUT ;
DR   Q3YRP7, FABH_EHRCJ ;  Q2GH17, FABH_EHRCR ;  Q5FFP2, FABH_EHRRG ;
DR   Q5HAV9, FABH_EHRRW ;  A4W9A5, FABH_ENT38 ;  A7MFQ4, FABH_ENTS8 ;
DR   Q5L1U1, FABH_GEOKA ;  Q0BTE0, FABH_GRABC ;  Q4QP30, FABH_HAEI8 ;
DR   A5UFW1, FABH_HAEIG ;  Q0I0V6, FABH_HAES1 ;  Q17YQ2, FABH_HELAH ;
DR   Q1CUV9, FABH_HELPH ;  A4G6T2, FABH_HERAR ;  Q0C312, FABH_HYPNA ;
DR   A6SXP9, FABH_JANMA ;  Q28RG1, FABH_JANSC ;  A6T7F1, FABH_KLEP7 ;
DR   Q03RV2, FABH_LACBA ;  A8YXS0, FABH_LACH4 ;  A2RM32, FABH_LACLM ;
DR   Q030J8, FABH_LACLS ;  Q38XG4, FABH_LACSS ;  A0AKV5, FABH_LISW6 ;
DR   Q2W4R7, FABH_MAGSA ;  A1U0E3, FABH_MARAV ;  A0QLF3, FABH_MYCA1 ;
DR   A1KG10, FABH_MYCBP ;  A5TZR3, FABH_MYCTA ;  A0PLS8, FABH_MYCUA ;
DR   Q5F4X5, FABH_NEIG1 ;  A1KRY9, FABH_NEIMF ;  Q2GDD8, FABH_NEOSM ;
DR   Q0AIS4, FABH_NITEC ;  Q2G5S1, FABH_NOVAD ;  A6LEP7, FABH_PARD8 ;
DR   A1B364, FABH_PARDP ;  Q3B6K8, FABH_PELLD ;  A1VRU7, FABH_POLNA ;
DR   Q126I8, FABH_POLSJ ;  A3PAK3, FABH_PROM0 ;  A8G2E1, FABH_PROM2 ;
DR   A2BUB2, FABH_PROM5 ;  Q31D45, FABH_PROM9 ;  Q46HN8, FABH_PROMT ;
DR   Q15TZ6, FABH_PSEA6 ;  Q02QG7, FABH_PSEAB ;  Q3IBW0, FABH_PSEHT ;
DR   A1STW1, FABH_PSYIN ;  Q21XP4, FABH_RHOFD ;  A3PJ64, FABH_RHOS1 ;
DR   Q3J365, FABH_RHOS4 ;  A4WTT9, FABH_RHOS5 ;  A8GPW1, FABH_RICAH ;
DR   A8GY06, FABH_RICB8 ;  A8EZX3, FABH_RICCK ;  A8F2R3, FABH_RICM5 ;
DR   A8GTP2, FABH_RICRS ;  Q164C9, FABH_ROSDO ;  Q1AW87, FABH_RUBXD ;
DR   Q57QG4, FABH_SALCH ;  Q5PGU1, FABH_SALPA ;  A8GD17, FABH_SERP5 ;
DR   Q31ZE6, FABH_SHIBS ;  Q32EV1, FABH_SHIDS ;  Q0T5U5, FABH_SHIF8 ;
DR   Q3Z326, FABH_SHISS ;  Q5LQJ5, FABH_SILPO ;  Q1GI69, FABH_SILST ;
DR   Q2NU42, FABH_SODGM ;  Q1GT90, FABH_SPHAL ;  A7X0K2, FABH_STAA1 ;
DR   Q2FI93, FABH_STAA3 ;  Q2FZS0, FABH_STAA8 ;  Q2YWV3, FABH_STAAB ;
DR   A6QFJ3, FABH_STAAE ;  Q3K338, FABH_STRA1 ;  Q04M58, FABH_STRP2 ;
DR   Q1JA87, FABH_STRPB ;  Q1JKE0, FABH_STRPC ;  Q1JFD2, FABH_STRPD ;
DR   Q1J582, FABH_STRPF ;  A2RCX0, FABH_STRPG ;  Q48RR7, FABH_STRPM ;
DR   A4W3N0, FABH_STRS2 ;  A3CQ60, FABH_STRSV ;  A4VXD4, FABH_STRSY ;
DR   Q5M184, FABH_STRT1 ;  Q5M5S1, FABH_STRT2 ;  Q03M55, FABH_STRTD ;
DR   Q30PN6, FABH_SULDN ;  Q31N84, FABH_SYNE7 ;  Q5N5X5, FABH_SYNP6 ;
DR   A5GP11, FABH_SYNPW ;  A5GQJ2, FABH_SYNR3 ;  Q0AVV3, FABH_SYNWW ;
DR   Q3SIM4, FABH_THIDA ;  Q114K0, FABH_TRIEI ;  A1WMX5, FABH_VEREI ;
DR   A5CWU7, FABH_VESOH ;  Q5E409, FABH_VIBF1 ;  Q5GS22, FABH_WOLTR ;
DR   Q3BWI9, FABH_XANC5 ;  Q4URQ0, FABH_XANC8 ;  Q2P7B9, FABH_XANOM ;
DR   A1JN67, FABH_YERE8 ;  A7FH25, FABH_YERP3 ;  Q1C6M8, FABH_YERPA ;
DR   Q1CI19, FABH_YERPN ;  A4TLS3, FABH_YERPP ;  Q669L1, FABH_YERPS ;
DR   P43098, FAS2_CANAL ;  P15368, FAS2_PENPA ;  Q10289, FAS2_SCHPO ;
DR   P19097, FAS2_YEAST ;  Q71SP7, FAS_BOVIN  ;  P12276, FAS_CHICK  ;
DR   P49327, FAS_HUMAN  ;  P19096, FAS_MOUSE  ;  P12785, FAS_RAT    ;
DR   P52410, KASC1_ARATH;  P23902, KASC1_HORVU;  Q9C9P4, KASC2_ARATH;
DR   Q8L3X9, KASM_ARATH ;  Q7TXK8, MSL7_MYCBO ;  B2HIL7, MSL7_MYCMM ;
DR   Q0VCA7, OXSM_BOVIN ;  Q9NWU1, OXSM_HUMAN ;  Q9D404, OXSM_MOUSE ;
DR   O94297, OXSM_SCHPO ;  Q7TXM0, PPSA_MYCBO ;  Q10977, PPSA_MYCTU ;
DR   Q7TXL9, PPSB_MYCBO ;  Q10978, PPSB_MYCTU ;  Q7TXL8, PPSC_MYCBO ;
DR   P96202, PPSC_MYCTU ;  Q7TXL7, PPSD_MYCBO ;  P96203, PPSD_MYCTU ;
DR   Q7TXL6, PPSE_MYCBO ;  P96204, PPSE_MYCTU ;
//
ID   2.3.1.42
DE   Glycerone-phosphate O-acyltransferase.
AN   Dihydroxyacetone phosphate acyltransferase.
CA   Acyl-CoA + glycerone phosphate = CoA + acylglycerone phosphate.
CC   -!- Uses CoA derivatives of palmitate, stearate, and oleate, with highest
CC       activity on palmitoyl-CoA.
DR   A4IF87, GNPAT_BOVIN;  O15228, GNPAT_HUMAN;  P98192, GNPAT_MOUSE;
DR   Q9ES71, GNPAT_RAT  ;  P32784, GPT1_YEAST ;  P36148, GPT2_YEAST ;
//
ID   2.3.1.43
DE   Phosphatidylcholine--sterol O-acyltransferase.
AN   LCAT.
AN   Lecithin--cholesterol acyltransferase.
AN   Phospholipid--cholesterol acyltransferase.
CA   Phosphatidylcholine + a sterol = 1-acylglycerophosphocholine +
CA   a sterol ester.
CC   -!- Palmitoyl, oleoyl, and linoleoyl can be transferred; a number of
CC       sterols, including cholesterol, can act as acceptors.
CC   -!- The bacterial enzyme also catalyzes the reactions of EC 3.1.1.4 and
CC       EC 3.1.1.5.
PR   PROSITE; PDOC00110;
DR   P10480, GCAT_AERHY ;  P53760, LCAT_CHICK ;  O35573, LCAT_ELIQU ;
DR   P04180, LCAT_HUMAN ;  O35724, LCAT_MICMN ;  P16301, LCAT_MOUSE ;
DR   O35502, LCAT_MYOGA ;  Q08758, LCAT_PAPAN ;  P30930, LCAT_PIG   ;
DR   P53761, LCAT_RABIT ;  P18424, LCAT_RAT   ;  O35840, LCAT_TATKG ;
//
ID   2.3.1.44
DE   N-acetylneuraminate 4-O-acetyltransferase.
CA   Acetyl-CoA + N-acetylneuraminate = CoA + N-acetyl-4-O-acetylneuraminate.
CC   -!- Both free and glycosidically bound N-acetyl- and N-glycolyl-
CC       neuraminates can act as O-acetyl acceptors.
//
ID   2.3.1.45
DE   N-acetylneuraminate 7-O(or 9-O)-acetyltransferase.
CA   Acetyl-CoA + N-acetylneuraminate = CoA + N-acetyl-7-O(or 9-O)-
CA   acetylneuraminate.
CC   -!- Both free and glycosidically bound N-acetyl- and
CC       N-glycolylneuraminates can act as O-acetyl acceptors.
//
ID   2.3.1.46
DE   Homoserine O-succinyltransferase.
AN   Homoserine O-transsuccinylase.
CA   Succinyl-CoA + L-homoserine = CoA + O-succinyl-L-homoserine.
DR   A0KFJ6, META_AERHH ;  A4SRY4, META_AERS4 ;  B9JDI5, META_AGRRK ;
DR   Q7CWE8, META_AGRT5 ;  B9JUF7, META_AGRVS ;  B6EKK3, META_ALISL ;
DR   B4RUL1, META_ALTMD ;  B6YQD4, META_AZOPC ;  A7Z5U1, META_BACA2 ;
DR   C3P2G5, META_BACAA ;  C3LFT4, META_BACAC ;  A0RLI8, META_BACAH ;
DR   B7JHN0, META_BACC0 ;  Q72X44, META_BACC1 ;  B7IRT5, META_BACC2 ;
DR   C1EQ75, META_BACC3 ;  B7HG67, META_BACC4 ;  B7HYG6, META_BACC7 ;
DR   A7GVF0, META_BACCN ;  Q814M3, META_BACCR ;  Q630J5, META_BACCZ ;
DR   Q5LHS7, META_BACFN ;  Q64YS9, META_BACFR ;  Q9KAK7, META_BACHD ;
DR   Q6HAN0, META_BACHK ;  Q65IA5, META_BACLD ;  A8FED0, META_BACP2 ;
DR   P54167, META_BACSU ;  Q8A531, META_BACTN ;  A6L1Z3, META_BACV8 ;
DR   A9VTE3, META_BACWK ;  Q491U9, META_BLOPB ;  C0Z4V3, META_BREBN ;
DR   B2SBF6, META_BRUA1 ;  Q2YKB2, META_BRUA2 ;  Q577P3, META_BRUAB ;
DR   A9MBD0, META_BRUC2 ;  C0RL20, META_BRUMB ;  Q8YBV5, META_BRUME ;
DR   A9WYG6, META_BRUSI ;  Q8FWG9, META_BRUSU ;  Q9PLV2, META_CAMJE ;
DR   A1W1X7, META_CAMJJ ;  Q5HS71, META_CAMJR ;  A8ANC0, META_CITK8 ;
DR   Q97I29, META_CLOAB ;  A6LSX9, META_CLOB8 ;  B2UXD0, META_CLOBA ;
DR   B2TPE3, META_CLOBB ;  B8I164, META_CLOCE ;  A0PY42, META_CLONN ;
DR   A9KPK9, META_CLOPH ;  Q895W4, META_CLOTE ;  A3DGI7, META_CLOTH ;
DR   B8IZQ7, META_DESDA ;  B8FWT4, META_DESHD ;  Q24NB7, META_DESHY ;
DR   A8LKX1, META_DINSH ;  A7ZUM6, META_ECO24 ;  B7UPG4, META_ECO27 ;
DR   B7MIZ5, META_ECO45 ;  B7LAV1, META_ECO55 ;  Q8X610, META_ECO57 ;
DR   B5Z0A5, META_ECO5E ;  B7NRU2, META_ECO7I ;  B7MRD7, META_ECO81 ;
DR   B7M7R7, META_ECO8A ;  C5A0V0, META_ECOBW ;  B1XC12, META_ECODH ;
DR   A8A7A9, META_ECOHS ;  A1AII3, META_ECOK1 ;  Q0TA56, META_ECOL5 ;
DR   Q8FB64, META_ECOL6 ;  B1IUN9, META_ECOLC ;  P07623, META_ECOLI ;
DR   B7NFU9, META_ECOLU ;  B6I5M1, META_ECOSE ;  B1LPH0, META_ECOSM ;
DR   Q1R3T4, META_ECOUT ;  C5BF07, META_EDWI9 ;  A4W5C7, META_ENT38 ;
DR   A7MPD4, META_ENTS8 ;  Q6D009, META_ERWCT ;  B2VK85, META_ERWT9 ;
DR   B7LKA1, META_ESCF3 ;  C4Z0T6, META_EUBE2 ;  C4ZCZ4, META_EUBR3 ;
DR   Q5KZ14, META_GEOKA ;  C5DAQ1, META_GEOSW ;  Q0BX37, META_HYPNA ;
DR   Q28PU4, META_JANSC ;  B5XYD0, META_KLEP3 ;  A6TGR5, META_KLEP7 ;
DR   Q9CEC5, META_LACLA ;  A2RN61, META_LACLM ;  B1HPA1, META_LYSSC ;
DR   Q11DS0, META_MESSB ;  Q2GAJ2, META_NOVAD ;  Q8ET26, META_OCEIH ;
DR   A6LC32, META_PARD8 ;  A1BAL9, META_PARDP ;  C6DFQ6, META_PECCP ;
DR   A9BFW1, META_PETMO ;  Q7MZ97, META_PHOLL ;  Q6LV74, META_PHOPR ;
DR   B4EYS9, META_PROMH ;  A1SR71, META_PSYIN ;  B3PRW0, META_RHIE6 ;
DR   Q1MAE9, META_RHIL3 ;  B5ZU74, META_RHILW ;  Q92L99, META_RHIME ;
DR   C3M9X0, META_RHISN ;  A3PK84, META_RHOS1 ;  Q3J205, META_RHOS4 ;
DR   A4WUJ2, META_RHOS5 ;  B9KT32, META_RHOSK ;  Q165M8, META_ROSDO ;
DR   B5F1J1, META_SALA4 ;  A9MHC0, META_SALAR ;  Q57H45, META_SALCH ;
DR   B5FQM3, META_SALDC ;  B5QYG3, META_SALEP ;  B5R7Q1, META_SALG2 ;
DR   B4TDF7, META_SALHS ;  B4T110, META_SALNS ;  Q5PKY6, META_SALPA ;
DR   A9N0M3, META_SALPB ;  C0Q486, META_SALPC ;  B5BJS7, META_SALPK ;
DR   B4TQL9, META_SALSV ;  Q8Z1W1, META_SALTI ;  P37413, META_SALTY ;
DR   A8GKF8, META_SERP5 ;  A1S5C5, META_SHEAM ;  B8E7M2, META_SHEB2 ;
DR   A3D2P8, META_SHEB5 ;  A6WLE9, META_SHEB8 ;  A9KVF7, META_SHEB9 ;
DR   Q12L09, META_SHEDO ;  Q084X6, META_SHEFN ;  B0TMS3, META_SHEHH ;
DR   A3QG19, META_SHELP ;  Q8EGC8, META_SHEON ;  A8H6B7, META_SHEPA ;
DR   A4Y589, META_SHEPC ;  B8CRT5, META_SHEPW ;  A0KYY0, META_SHESA ;
DR   A8FTB0, META_SHESH ;  Q0HGZ8, META_SHESM ;  Q0HTA5, META_SHESR ;
DR   A1RLI0, META_SHESW ;  B1KMU6, META_SHEWM ;  B2TWJ5, META_SHIB3 ;
DR   Q31TY9, META_SHIBS ;  Q328N3, META_SHIDS ;  Q0SXZ2, META_SHIF8 ;
DR   Q3YUX6, META_SHISS ;  Q5LSN6, META_SILPO ;  Q1GGV4, META_SILST ;
DR   Q2NQZ8, META_SODGM ;  A5V3T8, META_SPHWW ;  A8AWY1, META_STRGC ;
DR   Q8DT96, META_STRMU ;  Q04JH2, META_STRP2 ;  B5E6L9, META_STRP4 ;
DR   C1C8G7, META_STRP7 ;  B1ICZ6, META_STRPI ;  B8ZLT8, META_STRPJ ;
DR   Q97PM9, META_STRPN ;  B2IR95, META_STRPS ;  Q8DP05, META_STRR6 ;
DR   A3CNR2, META_STRSV ;  Q5LZD5, META_STRT1 ;  Q5M3Y7, META_STRT2 ;
DR   Q03K93, META_STRTD ;  C1CFF9, META_STRZJ ;  C1CLS5, META_STRZP ;
DR   C1CSJ6, META_STRZT ;  Q31RB6, META_SYNE7 ;  Q5N2Y8, META_SYNP6 ;
DR   Q9WZY3, META_THEMA ;  B9KA88, META_THENN ;  A5IIQ2, META_THEP1 ;
DR   B1LCF0, META_THESQ ;  C4L881, META_TOLAT ;  Q9KRM5, META_VIBCH ;
DR   B5FA49, META_VIBFM ;  A7N0F0, META_VIBHB ;  Q87NW7, META_VIBPA ;
DR   B7VPB2, META_VIBSL ;  Q8D937, META_VIBVU ;  Q7MLD5, META_VIBVY ;
DR   A1JRX9, META_YERE8 ;  A7FDF8, META_YERP3 ;  Q1CC38, META_YERPA ;
DR   B2K4Z5, META_YERPB ;  Q8ZAR4, META_YERPE ;  A9R941, META_YERPG ;
DR   Q1CNT5, META_YERPN ;  A4TH30, META_YERPP ;  Q664W1, META_YERPS ;
DR   B1JJL9, META_YERPY ;
//
ID   2.3.1.47
DE   8-amino-7-oxononanoate synthase.
AN   7-KAP synthetase.
AN   7-keto-8-aminopelargonic acid synthetase.
AN   8-amino-7-ketopelargonate synthase.
AN   AONS.
CA   6-carboxyhexanoyl-CoA + L-alanine = 8-amino-7-oxononanoate + CoA + CO(2).
CF   Pyridoxal 5'-phosphate.
PR   PROSITE; PDOC00518;
DR   A6TU88, BIKB_ALKMQ ;  A8MEX7, BIKB_ALKOO ;  A7Z4X1, BIKB_BACA2 ;
DR   A8FDG9, BIKB_BACP2 ;  O31777, BIKB_BACSU ;  B2IH50, BIKB_BEII9 ;
DR   B3QLR6, BIKB_CHLP8 ;  B5Y9Z4, BIKB_COPPD ;  P0AB78, BIKB_ECO57 ;
DR   B1YMC6, BIKB_EXIS2 ;  A7HMM1, BIKB_FERNB ;  A9HJ57, BIKB_GLUDA ;
DR   Q0BUV6, BIKB_GRABC ;  Q7VL09, BIKB_HAEDU ;  Q9ZLN3, BIKB_HELPJ ;
DR   O25320, BIKB_HELPY ;  B7L0L2, BIKB_METC4 ;  A9W106, BIKB_METEP ;
DR   B8IBW2, BIKB_METNO ;  B1Z7Y8, BIKB_METPB ;  B1LYP9, BIKB_METRJ ;
DR   B0UKC8, BIKB_METS4 ;  B8ERL9, BIKB_METSB ;  A0QHJ9, BIKB_MYCA1 ;
DR   P0A4X5, BIKB_MYCBO ;  A1KJ00, BIKB_MYCBP ;  A4T9L3, BIKB_MYCGI ;
DR   B8ZR84, BIKB_MYCLB ;  P45487, BIKB_MYCLE ;  B2HQ90, BIKB_MYCMM ;
DR   Q740R7, BIKB_MYCPA ;  A0QX65, BIKB_MYCS2 ;  A3Q146, BIKB_MYCSJ ;
DR   A1UHM3, BIKB_MYCSK ;  Q1B7F0, BIKB_MYCSS ;  A5U2S6, BIKB_MYCTA ;
DR   A5WMQ5, BIKB_MYCTF ;  P0A4X4, BIKB_MYCTU ;  A0PP02, BIKB_MYCUA ;
DR   A1T8U6, BIKB_MYCVP ;  A9BGL0, BIKB_PETMO ;  P37419, BIKB_SALTY ;
DR   P0AB79, BIKB_SHIFL ;  Q67N86, BIKB_SYMTH ;  B7ID58, BIKB_THEAB ;
DR   A6LMP4, BIKB_THEM4 ;  B0KC20, BIKB_THEP3 ;  B0K590, BIKB_THEPX ;
DR   Q5SHZ8, BIKB_THET8 ;  Q73KM3, BIKB_TREDE ;  Q12F38, BIOF1_POLSJ;
DR   Q12D74, BIOF2_POLSJ;  B0C205, BIOF_ACAM1 ;  A1TTV0, BIOF_ACIAC ;
DR   A5FZN8, BIOF_ACICJ ;  B7J3Y7, BIOF_ACIF2 ;  B5ELF7, BIOF_ACIF5 ;
DR   A0KIC7, BIOF_AERHH ;  A4SPR6, BIOF_AERS4 ;  Q0VMD1, BIOF_ALCBS ;
DR   Q0A5W2, BIOF_ALHEH ;  B6ESC6, BIOF_ALISL ;  B8J637, BIOF_ANAD2 ;
DR   Q2IF62, BIOF_ANADE ;  A7HG96, BIOF_ANADF ;  B4UCB1, BIOF_ANASK ;
DR   Q3M9A4, BIOF_ANAVT ;  B7GHW7, BIOF_ANOFW ;  O66875, BIOF_AQUAE ;
DR   Q5NZF5, BIOF_AROAE ;  A1K6Q1, BIOF_AZOSB ;  A7Z5B4, BIOF_BACA2 ;
DR   A0RIB9, BIOF_BACAH ;  Q81MB0, BIOF_BACAN ;  B7JLX2, BIOF_BACC0 ;
DR   Q731H9, BIOF_BACC1 ;  B7IWN1, BIOF_BACC2 ;  B7HAZ0, BIOF_BACC4 ;
DR   B7HNN4, BIOF_BACC7 ;  A7GSE1, BIOF_BACCN ;  B9IWY0, BIOF_BACCQ ;
DR   Q818X0, BIOF_BACCR ;  Q635G4, BIOF_BACCZ ;  Q9K625, BIOF_BACHD ;
DR   Q6HE48, BIOF_BACHK ;  Q65ML1, BIOF_BACLD ;  Q8KZM9, BIOF_BACNA ;
DR   P53556, BIOF_BACSU ;  A9VG56, BIOF_BACWK ;  Q7WH76, BIOF_BORBR ;
DR   Q7W9I4, BIOF_BORPA ;  A9HVE9, BIOF_BORPD ;  Q7VWP1, BIOF_BORPE ;
DR   Q89AK6, BIOF_BUCBP ;  B1YNS0, BIOF_BURA4 ;  Q1BT36, BIOF_BURCA ;
DR   B1JZD9, BIOF_BURCC ;  A0KB03, BIOF_BURCH ;  B4E9L6, BIOF_BURCJ ;
DR   Q0BBD6, BIOF_BURCM ;  A9AE46, BIOF_BURM1 ;  A3MNG3, BIOF_BURM7 ;
DR   A2S7R1, BIOF_BURM9 ;  Q62MX1, BIOF_BURMA ;  A1V819, BIOF_BURMS ;
DR   A3NQS3, BIOF_BURP0 ;  Q3JWR6, BIOF_BURP1 ;  A3N522, BIOF_BURP6 ;
DR   B2JKH6, BIOF_BURP8 ;  B2SWS7, BIOF_BURPP ;  Q63Y23, BIOF_BURPS ;
DR   Q39CE6, BIOF_BURS3 ;  Q2T1Q2, BIOF_BURTA ;  A4JIB5, BIOF_BURVG ;
DR   Q146K3, BIOF_BURXL ;  B8GVE2, BIOF_CAUCN ;  Q9A7Z1, BIOF_CAUCR ;
DR   B0SZS9, BIOF_CAUSK ;  B3PI88, BIOF_CELJU ;  Q1QYD6, BIOF_CHRSD ;
DR   Q7NPW2, BIOF_CHRVO ;  A8AJ11, BIOF_CITK8 ;  A3DBD5, BIOF_CLOTH ;
DR   Q0KF88, BIOF_CUPNH ;  Q477A3, BIOF_CUPPJ ;  B2AG98, BIOF_CUPTR ;
DR   B8HTV6, BIOF_CYAP4 ;  B7KD70, BIOF_CYAP7 ;  B7K0L9, BIOF_CYAP8 ;
DR   Q47C04, BIOF_DECAR ;  A9BV10, BIOF_DELAS ;  B1I4F9, BIOF_DESAP ;
DR   B8J3V0, BIOF_DESDA ;  A8ZUS7, BIOF_DESOH ;  A7ZJI5, BIOF_ECO24 ;
DR   B7ULX3, BIOF_ECO27 ;  B7MGN4, BIOF_ECO45 ;  B7LC58, BIOF_ECO55 ;
DR   Q8X823, BIOF_ECO57 ;  B5YRL5, BIOF_ECO5E ;  B7NNK6, BIOF_ECO7I ;
DR   B7MQM9, BIOF_ECO81 ;  B7M748, BIOF_ECO8A ;  B1X7A6, BIOF_ECODH ;
DR   A7ZY32, BIOF_ECOHS ;  A1A918, BIOF_ECOK1 ;  Q0TJS2, BIOF_ECOL5 ;
DR   Q8FJQ2, BIOF_ECOL6 ;  B1IXJ2, BIOF_ECOLC ;  P12998, BIOF_ECOLI ;
DR   B7NA75, BIOF_ECOLU ;  B6I7T0, BIOF_ECOSE ;  B1LM67, BIOF_ECOSM ;
DR   Q1REF4, BIOF_ECOUT ;  A4W8B8, BIOF_ENT38 ;  Q47829, BIOF_ENTAG ;
DR   A7MJ02, BIOF_ENTS8 ;  Q6D3C0, BIOF_ERWCT ;  B2VBT8, BIOF_ERWT9 ;
DR   B7LJY7, BIOF_ESCF3 ;  B5EEV8, BIOF_GEOBB ;  Q5KY23, BIOF_GEOKA ;
DR   B3EAE0, BIOF_GEOLS ;  Q39XE0, BIOF_GEOMG ;  B9M8U3, BIOF_GEOSF ;
DR   Q749W3, BIOF_GEOSL ;  A5G6I9, BIOF_GEOUR ;  Q7NNL4, BIOF_GLOVI ;
DR   Q4QKR3, BIOF_HAEI8 ;  A5UCE4, BIOF_HAEIE ;  A5UJ44, BIOF_HAEIG ;
DR   P44422, BIOF_HAEIN ;  B8F713, BIOF_HAEPS ;  Q2SBD5, BIOF_HAHCH ;
DR   A1WVM6, BIOF_HALHL ;  A4G5N9, BIOF_HERAR ;  A6SU64, BIOF_JANMA ;
DR   B5XZ74, BIOF_KLEP3 ;  A6T6L6, BIOF_KLEP7 ;  B1Y500, BIOF_LEPCP ;
DR   P22806, BIOF_LYSSH ;  Q2W3L2, BIOF_MAGSA ;  A0L3L7, BIOF_MAGSM ;
DR   A1U4B1, BIOF_MARAV ;  Q0APZ9, BIOF_MARMM ;  A6W0Y0, BIOF_MARMS ;
DR   A6UWX3, BIOF_META3 ;  Q609V1, BIOF_METCA ;  Q1GZA7, BIOF_METFK ;
DR   Q58694, BIOF_METJA ;  A2SD53, BIOF_METPP ;  A6UQL9, BIOF_METVS ;
DR   B0JQZ0, BIOF_MICAN ;  Q1DCV8, BIOF_MYXXD ;  Q5F6R6, BIOF_NEIG1 ;
DR   B4RP93, BIOF_NEIG2 ;  A9M251, BIOF_NEIM0 ;  A1ITK1, BIOF_NEIMA ;
DR   Q9K0U0, BIOF_NEIMB ;  A1KVF6, BIOF_NEIMF ;  Q0AE73, BIOF_NITEC ;
DR   Q81ZZ4, BIOF_NITEU ;  Q2Y9Y8, BIOF_NITMU ;  Q3J9D6, BIOF_NITOC ;
DR   B2J1W1, BIOF_NOSP7 ;  Q8YZT3, BIOF_NOSS1 ;  A7HP29, BIOF_PARL1 ;
DR   Q9CJU0, BIOF_PASMU ;  Q3A3Z8, BIOF_PELCD ;  A1AQT1, BIOF_PELPD ;
DR   B4RFX5, BIOF_PHEZH ;  Q7N6Q6, BIOF_PHOLL ;  Q6LPR3, BIOF_PHOPR ;
DR   A1VUJ6, BIOF_POLNA ;  B4ESU4, BIOF_PROMH ;  Q48CS2, BIOF_PSE14 ;
DR   A6UYW1, BIOF_PSEA7 ;  B7V486, BIOF_PSEA8 ;  Q02TR5, BIOF_PSEAB ;
DR   Q9I617, BIOF_PSEAE ;  Q1I3N7, BIOF_PSEE4 ;  Q4K4T3, BIOF_PSEF5 ;
DR   A4XZR8, BIOF_PSEMY ;  A5VXF2, BIOF_PSEP1 ;  Q3K5P2, BIOF_PSEPF ;
DR   B0KJ54, BIOF_PSEPG ;  Q88QX1, BIOF_PSEPK ;  B1JE54, BIOF_PSEPW ;
DR   Q88A97, BIOF_PSESM ;  Q4ZMA9, BIOF_PSEU2 ;  A4VR87, BIOF_PSEU5 ;
DR   Q1LS75, BIOF_RALME ;  B2UBJ3, BIOF_RALPJ ;  Q8XZC3, BIOF_RALSO ;
DR   Q21FY4, BIOF_SACD2 ;  B5F073, BIOF_SALA4 ;  A9MJE5, BIOF_SALAR ;
DR   Q57RG2, BIOF_SALCH ;  B5FP62, BIOF_SALDC ;  B5QX66, BIOF_SALEP ;
DR   B5R762, BIOF_SALG2 ;  B4TC49, BIOF_SALHS ;  B4SZJ8, BIOF_SALNS ;
DR   Q5PG49, BIOF_SALPA ;  A9MTI7, BIOF_SALPB ;  C0PWY3, BIOF_SALPC ;
DR   B5BC30, BIOF_SALPK ;  B4TQU0, BIOF_SALSV ;  Q8Z892, BIOF_SALTI ;
DR   Q8ZQQ7, BIOF_SALTY ;  P36570, BIOF_SERMA ;  A8GBC6, BIOF_SERP5 ;
DR   B2TVF4, BIOF_SHIB3 ;  Q324B6, BIOF_SHIBS ;  Q32I45, BIOF_SHIDS ;
DR   Q0T6I4, BIOF_SHIF8 ;  Q83S45, BIOF_SHIFL ;  Q3Z408, BIOF_SHISS ;
DR   Q2NUJ6, BIOF_SODGM ;  B4SM82, BIOF_STRM5 ;  B2FLM5, BIOF_STRMK ;
DR   B1XL23, BIOF_SYNP2 ;  P74770, BIOF_SYNY3 ;  Q8DJ97, BIOF_THEEB ;
DR   B5YFU5, BIOF_THEYD ;  Q31E54, BIOF_THICR ;  Q3SLX9, BIOF_THIDA ;
DR   B8GTH6, BIOF_THISH ;  Q119K2, BIOF_TRIEI ;  Q9KSZ3, BIOF_VIBCH ;
DR   Q5DZH9, BIOF_VIBF1 ;  B5EUP9, BIOF_VIBFM ;  A7MX30, BIOF_VIBHB ;
DR   Q87QN5, BIOF_VIBPA ;  B7VH15, BIOF_VIBSL ;  Q8D8N0, BIOF_VIBVU ;
DR   Q7MLU9, BIOF_VIBVY ;  Q8PQD8, BIOF_XANAC ;  Q3BYN0, BIOF_XANC5 ;
DR   Q4UZN9, BIOF_XANC8 ;  B0RMR1, BIOF_XANCB ;  Q8PDF1, BIOF_XANCP ;
DR   Q2P8F2, BIOF_XANOM ;  B2SS66, BIOF_XANOP ;  Q5H5R0, BIOF_XANOR ;
DR   B2I9H7, BIOF_XYLF2 ;  Q9PDM2, BIOF_XYLFA ;  B0U6J0, BIOF_XYLFM ;
DR   Q87DT2, BIOF_XYLFT ;  A1JS67, BIOF_YERE8 ;  A7FKM8, BIOF_YERP3 ;
DR   Q1C946, BIOF_YERPA ;  B2K8T1, BIOF_YERPB ;  Q7CH66, BIOF_YERPE ;
DR   A9R3C9, BIOF_YERPG ;  Q1CFQ4, BIOF_YERPN ;  A4TNQ5, BIOF_YERPP ;
DR   Q66D66, BIOF_YERPS ;  B1JSS3, BIOF_YERPY ;  C4LK80, BIOWF_CORK4;
DR   Q6A6M4, BIOWF_PROAC;  D4H9Y2, BIOWF_PROAS;
//
ID   2.3.1.48
DE   Histone acetyltransferase.
CA   Acetyl-CoA + [histone] = CoA + acetyl-[histone].
CC   -!- A group of enzymes with differing specificities toward histone
CC       acceptors.
DR   Q92793, CBP_HUMAN  ;  P45481, CBP_MOUSE  ;  Q6JHU9, CBP_RAT    ;
DR   Q9Y6F8, CDY1_HUMAN ;  Q9Y6F7, CDY2_HUMAN ;  Q9Y232, CDYL1_HUMAN;
DR   Q9WTK2, CDYL_MOUSE ;  Q6AYK9, CDYL_RAT   ;  O15516, CLOCK_HUMAN;
DR   O08785, CLOCK_MOUSE;  Q91YB0, CLOCK_NANGA;  Q5RAK8, CLOCK_PONAB;
DR   Q9WVS9, CLOCK_RAT  ;  Q91YB2, CLOCK_SPACA;  Q91YA8, CLOCK_SPAJD;
DR   Q93ZR1, ELP3_ARATH ;  Q2KJ61, ELP3_BOVIN ;  Q60LW7, ELP3_CAEBR ;
DR   Q23651, ELP3_CAEEL ;  Q5ZHS1, ELP3_CHICK ;  Q5RIC0, ELP3_DANRE ;
DR   Q1ZXC6, ELP3_DICDI ;  Q9VQZ6, ELP3_DROME ;  Q9H9T3, ELP3_HUMAN ;
DR   Q9CZX0, ELP3_MOUSE ;  Q7X7L3, ELP3_ORYSJ ;  O14023, ELP3_SCHPO ;
DR   Q5HZM6, ELP3_XENLA ;  Q6NVL5, ELP3_XENTR ;  Q02908, ELP3_YEAST ;
DR   Q09472, EP300_HUMAN;  B2RWS6, EP300_MOUSE;  Q75BY2, ESA1_ASHGO ;
DR   Q4WHG1, ESA1_ASPFU ;  Q2UMQ5, ESA1_ASPOR ;  Q5A7Q2, ESA1_CANAL ;
DR   Q6FPH9, ESA1_CANGA ;  P0CP03, ESA1_CRYNB ;  P0CP02, ESA1_CRYNJ ;
DR   Q6BU95, ESA1_DEBHA ;  Q4IEV4, ESA1_GIBZE ;  Q6CKE9, ESA1_KLULA ;
DR   Q7S9B6, ESA1_NEUCR ;  O94446, ESA1_SCHPO ;  Q4P3S3, ESA1_USTMA ;
DR   Q6C710, ESA1_YARLI ;  Q08649, ESA1_YEAST ;  Q9AR19, GCN5_ARATH ;
DR   Q756G9, GCN5_ASHGO ;  Q6FTW5, GCN5_CANGA ;  Q6BGW1, GCN5_DEBHA ;
DR   Q6CXW4, GCN5_KLULA ;  Q338B9, GCN5_ORYSJ ;  Q9UUK2, GCN5_SCHPO ;
DR   Q8WZM0, GCN5_YARLI ;  Q03330, GCN5_YEAST ;  Q9FWQ5, HAC12_ARATH;
DR   Q9C5X9, HAC1_ARATH ;  Q9FYH1, HAC2_ARATH ;  Q9LG11, HAC4_ARATH ;
DR   Q9LE42, HAC5_ARATH ;  Q6YXY2, HACL1_ORYSJ;  Q5Z8V7, HACL2_ORYSJ;
DR   Q9XHY7, HACL3_ORYSJ;  Q86J12, HAT11_DICDI;  Q869X7, HAT12_DICDI;
DR   Q750F5, HAT1_ASHGO ;  Q4X0W8, HAT1_ASPFU ;  Q2UEX1, HAT1_ASPOR ;
DR   Q59VF4, HAT1_CANAL ;  Q6FKS5, HAT1_CANGA ;  P0CO07, HAT1_CRYNB ;
DR   P0CO06, HAT1_CRYNJ ;  Q6BSQ1, HAT1_DEBHA ;  Q5AZR6, HAT1_EMENI ;
DR   Q4I6A4, HAT1_GIBZE ;  O14929, HAT1_HUMAN ;  Q6CN95, HAT1_KLULA ;
DR   Q8LPU4, HAT1_MAIZE ;  Q8BY71, HAT1_MOUSE ;  Q7RYU8, HAT1_NEUCR ;
DR   Q6ES10, HAT1_ORYSJ ;  Q5M939, HAT1_RAT   ;  Q9UTM7, HAT1_SCHPO ;
DR   Q4PBE6, HAT1_USTMA ;  Q6CC99, HAT1_YARLI ;  Q12341, HAT1_YEAST ;
DR   Q9FJT8, HATB_ARATH ;  Q06592, HPA2_YEAST ;  Q92830, KAT2A_HUMAN;
DR   Q9JHD2, KAT2A_MOUSE;  Q92831, KAT2B_HUMAN;  Q9JHD1, KAT2B_MOUSE;
DR   Q92993, KAT5_HUMAN ;  Q8CHK4, KAT5_MOUSE ;  Q5RBG4, KAT5_PONAB ;
DR   Q99MK2, KAT5_RAT   ;  Q9SGH2, MBD9_ARATH ;  Q10325, MST2_SCHPO ;
DR   Q9FLF7, MYST1_ARATH;  Q9H7Z6, MYST1_HUMAN;  Q9D1P2, MYST1_MOUSE;
DR   Q8LI34, MYST1_ORYSJ;  Q5XI06, MYST1_RAT  ;  Q9LXD7, MYST2_ARATH;
DR   O95251, MYST2_HUMAN;  Q5SVQ0, MYST2_MOUSE;  Q810T5, MYST2_RAT  ;
DR   Q92794, MYST3_HUMAN;  Q8BZ21, MYST3_MOUSE;  Q5TKR9, MYST3_RAT  ;
DR   Q8WYB5, MYST4_HUMAN;  Q8WML3, MYST4_MACFA;  Q8BRB7, MYST4_MOUSE;
DR   Q15788, NCOA1_HUMAN;  P70365, NCOA1_MOUSE;  Q4PJW2, NCOA1_PIG  ;
DR   Q9Y6Q9, NCOA3_HUMAN;  O09000, NCOA3_MOUSE;  Q9EPU2, NCOA3_RAT  ;
DR   O57539, NCOA3_XENLA;  O60502, NCOAT_HUMAN;  Q9EQQ9, NCOAT_MOUSE;
DR   Q8VIJ5, NCOAT_RAT  ;  Q9Y7Y5, RT109_SCHPO;  Q07794, RT109_YEAST;
DR   P40963, SAS2_YEAST ;  P34218, SAS3_YEAST ;  P46677, TAF1_YEAST ;
DR   Q9UKN8, TF3C4_HUMAN;  Q8BMQ2, TF3C4_MOUSE;  Q9TYU5, TIP60_CAEEL;
DR   Q960X4, TIP60_DROME;
//
ID   2.3.1.49
DE   Deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase.
CA   S-acetylphosphopantotheine + deacetyl-[citrate-oxaloacetate-lyase((pro-
CA   3S)-CH(2)COO(-)->acetate)] = phosphopantotheine + [citrate-oxaloacetate-
CA   lyase((pro-3S)-CH(2)COO(-)->acetate)].
CC   -!- Both this enzyme and EC 6.2.1.22 acetylate and activate EC 4.1.3.6.
//
ID   2.3.1.50
DE   Serine C-palmitoyltransferase.
CA   Palmitoyl-CoA + L-serine = CoA + 3-dehydro-D-sphinganine + CO(2).
CF   Pyridoxal 5'-phosphate.
PR   PROSITE; PDOC00518;
DR   O59682, LCB1_SCHPO ;  P25045, LCB1_YEAST ;  P48241, LCB2_KLULA ;
DR   Q09925, LCB2_SCHPO ;  P40970, LCB2_YEAST ;  Q3MHG1, SPTC1_BOVIN;
DR   O54695, SPTC1_CRIGR;  Q55FL5, SPTC1_DICDI;  O15269, SPTC1_HUMAN;
DR   Q60HD1, SPTC1_MACFA;  O35704, SPTC1_MOUSE;  Q5R9T5, SPTC1_PONAB;
DR   O54694, SPTC2_CRIGR;  Q54EX5, SPTC2_DICDI;  O15270, SPTC2_HUMAN;
DR   P97363, SPTC2_MOUSE;  Q9NUV7, SPTC3_HUMAN;  Q8BG54, SPTC3_MOUSE;
//
ID   2.3.1.51
DE   1-acylglycerol-3-phosphate O-acyltransferase.
CA   Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol
CA   3-phosphate.
CC   -!- Acyl-[acyl-carrier-protein] can also act as acyl donor.
CC   -!- The animal enzyme is specific for the transfer of unsaturated fatty
CC       acyl groups.
DR   Q8WTS1, ABHD5_HUMAN;  Q9DBL9, ABHD5_MOUSE;  Q5EE05, ABHD5_PIG  ;
DR   Q5RBI4, ABHD5_PONAB;  Q6QA69, ABHD5_RAT  ;  O42916, ALE1_SCHPO ;
DR   Q08548, ALE1_YEAST ;  Q12385, ICT1_YEAST ;  Q5F3X0, LCLT1_CHICK;
DR   Q6NYV8, LCLT1_DANRE;  Q6UWP7, LCLT1_HUMAN;  Q3UN02, LCLT1_MOUSE;
DR   Q8GXU8, LPAT1_ARATH;  Q9LLY4, LPAT1_BRANA;  Q8LG50, LPAT2_ARATH;
DR   Q9XFW4, LPAT2_BRANA;  Q6IWY1, LPAT2_BRAOL;  Q9SYC8, LPAT3_ARATH;
DR   Q8L4Y2, LPAT4_ARATH;  Q9LHN4, LPAT5_ARATH;  Q41745, LPAT_MAIZE ;
DR   Q6ZWT7, MBOA2_HUMAN;  Q11087, PLC12_CAEEL;  Q93841, PLC1_CAEEL ;
DR   Q22267, PLC2_CAEEL ;  Q95JH2, PLCA_BOVIN ;  Q99943, PLCA_HUMAN ;
DR   O35083, PLCA_MOUSE ;  Q95JH0, PLCA_SHEEP ;  O15120, PLCB_HUMAN ;
DR   Q8K3K7, PLCB_MOUSE ;  Q9NRZ7, PLCC_HUMAN ;  Q9D517, PLCC_MOUSE ;
DR   Q5RA57, PLCC_PONAB ;  Q5E9R2, PLCD_BOVIN ;  Q9NRZ5, PLCD_HUMAN ;
DR   Q4R581, PLCD_MACFA ;  Q8K4X7, PLCD_MOUSE ;  Q5R757, PLCD_PONAB ;
DR   Q924S1, PLCD_RAT   ;  Q9NUQ2, PLCE_HUMAN ;  Q9D1E8, PLCE_MOUSE ;
DR   Q59188, PLSC_BORBU ;  Q42670, PLSC_COCNU ;  P26647, PLSC_ECOLI ;
DR   P44848, PLSC_HAEIN ;  Q9ZJN8, PLSC_HELPJ ;  O25903, PLSC_HELPY ;
DR   Q42868, PLSC_LIMAL ;  Q42870, PLSC_LIMDO ;  Q49402, PLSC_MYCGE ;
DR   P75479, PLSC_MYCPN ;  Q59601, PLSC_NEIGO ;  Q9JU41, PLSC_NEIMA ;
DR   Q9JZ47, PLSC_NEIMB ;  P0A258, PLSC_SALTI ;  P0A257, PLSC_SALTY ;
DR   P33333, PLSC_YEAST ;
//
ID   2.3.1.52
DE   2-acylglycerol-3-phosphate O-acyltransferase.
CA   Acyl-CoA + 2-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol
CA   3-phosphate.
CC   -!- Saturated acyl-CoA thioesters are the most effective acyl donors.
//
ID   2.3.1.53
DE   Phenylalanine N-acetyltransferase.
CA   Acetyl-CoA + L-phenylalanine = CoA + N-acetyl-L-phenylalanine.
CC   -!- Also acts, more slowly, on L-histidine and L-alanine.
//
ID   2.3.1.54
DE   Formate C-acetyltransferase.
AN   Pyruvate formate-lyase.
CA   Acetyl-CoA + formate = CoA + pyruvate.
PR   PROSITE; PDOC00665;
DR   P09373, PFLB_ECOLI ;  P43753, PFLB_HAEIN ;  Q2FK44, PFLB_STAA3 ;
DR   Q2G1D8, PFLB_STAA8 ;  Q2YV53, PFLB_STAAB ;  Q5HJF4, PFLB_STAAC ;
DR   Q99WZ7, PFLB_STAAM ;  Q7A7X6, PFLB_STAAN ;  Q6GK90, PFLB_STAAR ;
DR   Q6GCQ0, PFLB_STAAS ;  Q7A1W9, PFLB_STAAW ;  Q5HKH9, PFLB_STAEQ ;
DR   Q8CTX6, PFLB_STAES ;  P32674, PFLD_ECOLI ;  P75793, PFLF_ECOLI ;
DR   P37836, PFL_CHLRE  ;  Q46266, PFL_CLOPA  ;  O32797, PFL_LACLA  ;
DR   O32799, PFL_LACLM  ;  Q59934, PFL_STRMU  ;
//
ID   2.3.1.55
DE   Transferred entry: 2.3.1.82.
//
ID   2.3.1.56
DE   Aromatic-hydroxylamine O-acetyltransferase.
CA   N-hydroxy-4-acetylaminobiphenyl + N-hydroxy-4-aminobiphenyl = N-hydroxy-
CA   4-aminobiphenyl + N-acetoxy-4-aminobiphenyl.
CC   -!- Transfers the N-acetyl group of some aromatic acethydroxamates to the
CC       O-position of some aromatic hydroxylamines.
//
ID   2.3.1.57
DE   Diamine N-acetyltransferase.
AN   Acetyl-coenzyme A-1,4-diaminobutane N-acetyltransferase.
AN   Diamine acetyltransferase.
AN   Putrescine (diamine)-acetylating enzyme.
AN   Putrescine acetylase.
AN   Putrescine acetyltransferase.
AN   Putrescine N-acetyltransferase.
AN   Spermidine acetyltransferase.
AN   Spermidine N(1)-acetyltransferase.
CA   Acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine.
CC   -!- Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine,
CC       spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)-
CC       acetylspermidine and N(8)-acetylspermidine.
DR   P0A952, ATDA_ECO57 ;  P0A951, ATDA_ECOLI ;  P39909, BLTD_BACSU ;
DR   Q3T0Q0, SAT1_BOVIN ;  Q8AXL1, SAT1_CHICK ;  Q9JHW6, SAT1_CRIGR ;
DR   P21673, SAT1_HUMAN ;  Q01612, SAT1_MESAU ;  P48026, SAT1_MOUSE ;
DR   P49431, SAT1_MUSSA ;  Q28999, SAT1_PIG   ;  Q7PCJ8, SAT2_BOVIN ;
DR   Q96F10, SAT2_HUMAN ;  Q6P8J2, SAT2_MOUSE ;  Q7PCJ9, SAT2_PIG   ;
//
ID   2.3.1.58
DE   2,3-diaminopropionate N-oxalyltransferase.
AN   ODAP synthase.
AN   Oxalyldiaminopropionate synthase.
AN   Oxalyldiaminopropionic synthase.
CA   Oxalyl-CoA + L-2,3-diaminopropanoate = CoA + N(3)-oxalyl-L-2,3-
CA   diaminopropanoate.
//
ID   2.3.1.59
DE   Gentamicin 2'-N-acetyltransferase.
AN   Gentamycin acetyltransferase II.
CA   Acetyl-CoA + gentamicin C(1a) = CoA + N(2')-acetylgentamicin C(1a).
CC   -!- The antibiotics gentamicin A, sisomicin, tobramycin, paromomycin,
CC       neomycin B, kanamycin B and kanamycin C can also act as acceptors.
DR   Q52424, AAC2_PROST ;
//
ID   2.3.1.60
DE   Gentamicin 3'-N-acetyltransferase.
AN   Aminoglycoside acetyltransferase AAC(3)-I.
AN   Gentamicin acetyltransferase I.
CA   Acetyl-CoA + gentamicin C = CoA + N(3')-acetylgentamicin C.
CC   -!- Also acetylates sisomicin.
DR   P23181, AACC1_PSEAE;
//
ID   2.3.1.61
DE   Dihydrolipoyllysine-residue succinyltransferase.
AN   Dihydrolipoamide S-succinyltransferase.
AN   Dihydrolipoamide succinyltransferase.
AN   Dihydrolipoic transsuccinylase.
AN   Dihydrolipolyl transsuccinylase.
AN   Dihydrolipoyl transsuccinylase.
AN   Lipoate succinyltransferase.
AN   Lipoic transsuccinylase.
AN   Lipoyl transsuccinylase.
AN   Succinyl-CoA:dihydrolipoamide S-succinyltransferase.
AN   Succinyl-CoA:dihydrolipoate S-succinyltransferase.
CA   Succinyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-
CA   (S-succinyldihydrolipoyl)lysine.
CC   -!- A multimer (24-mer) of this enzyme forms the core of the multienzyme
CC       complex, and binds tightly both EC 1.2.4.2 and EC 1.8.1.4.
CC   -!- The lipoyl group of this enzyme is reductively succinylated by
CC       EC 1.2.4.2, and the only observed direction catalyzed by EC 2.3.1.61
CC       is that where this succinyl group is passed to coenzyme A.
DR   Q9FLQ4, ODO2A_ARATH;  Q8H107, ODO2B_ARATH;  P20708, ODO2_AZOVI ;
DR   P16263, ODO2_BACSU ;  Q6FYD4, ODO2_BARQU ;  Q8GCY1, ODO2_BARVB ;
DR   P11179, ODO2_BOVIN ;  P57389, ODO2_BUCAI ;  Q8K9N2, ODO2_BUCAP ;
DR   Q89AJ6, ODO2_BUCBP ;  P52993, ODO2_CUPNH ;  P83708, ODO2_DELAC ;
DR   Q869Y7, ODO2_DICDI ;  P0AFG7, ODO2_ECO57 ;  P0AFG6, ODO2_ECOLI ;
DR   P45302, ODO2_HAEIN ;  P36957, ODO2_HUMAN ;  P86219, ODO2_MESAU ;
DR   Q9D2G2, ODO2_MOUSE ;  P65634, ODO2_MYCBO ;  P65633, ODO2_MYCTU ;
DR   Q9N0F1, ODO2_PIG   ;  Q9I3D2, ODO2_PSEAE ;  P31051, ODO2_PSEPU ;
DR   Q01205, ODO2_RAT   ;  Q1RHI5, ODO2_RICBR ;  Q92J43, ODO2_RICCN ;
DR   Q4UKI7, ODO2_RICFE ;  Q9ZDY4, ODO2_RICPR ;  Q68XI8, ODO2_RICTY ;
DR   O94681, ODO2_SCHPO ;  P81896, ODO2_SOLTU ;  Q2FH26, ODO2_STAA3 ;
DR   Q2FYM2, ODO2_STAA8 ;  Q2YY06, ODO2_STAAB ;  Q5HG07, ODO2_STAAC ;
DR   Q99U75, ODO2_STAAM ;  Q7A5N4, ODO2_STAAN ;  Q6GGZ6, ODO2_STAAR ;
DR   Q6G9E9, ODO2_STAAS ;  Q8NWR7, ODO2_STAAW ;  Q5HPC7, ODO2_STAEQ ;
DR   Q8CSL9, ODO2_STAES ;  Q4L6C3, ODO2_STAHJ ;  Q49XM4, ODO2_STAS1 ;
DR   Q90512, ODO2_TAKRU ;  P19262, ODO2_YEAST ;
//
ID   2.3.1.62
DE   2-acylglycerophosphocholine O-acyltransferase.
CA   Acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine = CoA +
CA   phosphatidylcholine.
//
ID   2.3.1.63
DE   1-alkylglycerophosphocholine O-acyltransferase.
CA   Acyl-CoA + 1-alkyl-sn-glycero-3-phosphocholine = CoA + 2-acyl-1-alkyl-
CA   sn-glycero-3-phosphocholine.
CC   -!- May be identical with EC 2.3.1.23.
//
ID   2.3.1.64
DE   Agmatine N(4)-coumaroyltransferase.
AN   Agmatine coumaroyltransferase.
AN   p-coumaroyl-CoA-agmatine N-p-coumaroyltransferase.
CA   4-coumaroyl-CoA + agmatine = CoA + N-(4-guanidinobutyl)-4-
CA   hydroxycinnamamide.
DR   A9ZPJ6, AGCT1_HORVU;  A9ZPJ7, AGCT2_HORVU;  Q9FNP9, AGCT_ARATH ;
//
ID   2.3.1.65
DE   Bile acid-CoA:amino acid N-acyltransferase.
AN   Amino acid N-choloyltransferase.
AN   BACAT.
AN   BAT.
AN   Cholyl-CoA glycine-taurine N-acyltransferase.
AN   Cholyl-CoA:taurine N-acyltransferase.
AN   Glycine N-choloyltransferase.
AN   Glycine--taurine N-acyltransferase.
CA   Choloyl-CoA + glycine = CoA + glycocholate.
CC   -!- Also acts on CoA derivatives of other bile acids.
CC   -!- Taurine and 2-fluoro-beta-alanine can act as substrates, but more
CC       slowly.
CC   -!- Can also conjugate fatty acids to glycine and can act as a very-long-
CC       chain acyl-CoA thioesterase.
CC   -!- Bile-acid--amino-acid conjugates serve as detergents in the
CC       gastrointestinal tract, solubilizing long chain fatty acids, mono-
CC       and diglycerides, fat-soluble vitamins and cholesterol.
CC   -!- This is the second enzyme in a two-step process leading to the
CC       conjugation of bile acids with amino acids; the first step is the
CC       conversion of bile acids into their acyl-CoA thioesters, which is
CC       catalyzed by EC 6.2.1.7.
DR   Q14032, BAAT_HUMAN ;  Q91X34, BAAT_MOUSE ;  Q63276, BAAT_RAT   ;
//
ID   2.3.1.66
DE   Leucine N-acetyltransferase.
CA   Acetyl-CoA + L-leucine = CoA + N-acetyl-L-leucine.
CC   -!- Propanoyl-CoA can act, more slowly, as donor.
CC   -!- L-arginine, L-valine, L-phenylalanine and peptides containing
CC       L-leucine can act as acceptor.
//
ID   2.3.1.67
DE   1-alkylglycerophosphocholine O-acetyltransferase.
AN   1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase.
AN   1-alkyl-2-lysolecithin acetyltransferase.
AN   Acetyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphocholine 2-O-
AN   acetyltransferase.
AN   Acetyl-CoA:lyso-PAF acetyltransferase.
AN   Acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acyltransferase.
AN   Blood platelet-activating factor acetyltransferase.
AN   Lyso-GPC:acetyl CoA acetyltransferase.
AN   Lyso-platelet activating factor:acetyl-CoA acetyltransferase.
AN   Lyso-platelet-activating factor:acetyl-CoA acetyltransferase.
AN   LysoPAF:acetyl CoA acetyltransferase.
AN   PAF acetyltransferase.
AN   Platelet-activating factor acylhydrolase.
AN   Platelet-activating factor-synthesizing enzyme.
CA   Acetyl-CoA + 1-alkyl-sn-glycero-3-phosphocholine = CoA + 2-acetyl-1-
CA   alkyl-sn-glycero-3-phosphocholine.
DR   Q1LWG4, PCAT1_DANRE;  Q8NF37, PCAT1_HUMAN;  Q3TFD2, PCAT1_MOUSE;
DR   Q1HAQ0, PCAT1_RAT  ;  Q502J0, PCAT2_DANRE;  Q7L5N7, PCAT2_HUMAN;
DR   Q8BYI6, PCAT2_MOUSE;  P0C1Q3, PCAT2_RAT  ;
//
ID   2.3.1.68
DE   Glutamine N-acyltransferase.
CA   Acyl-CoA + L-glutamine = CoA + N-acyl-L-glutamine.
CC   -!- Phenylacetyl-CoA and (indol-3-yl)acetyl-CoA, but not benzoyl-CoA,
CC       can act as acyl donor.
CC   -!- Not identical with EC 2.3.1.13 or EC 2.3.1.71.
//
ID   2.3.1.69
DE   Monoterpenol O-acetyltransferase.
AN   Menthol transacetylase.
CA   Acetyl-CoA + a monoterpenol = CoA + a monoterpenol acetate ester.
CC   -!- (-)-menthol, (+)-neomenthol, borneol, cyclohexanol and N-decanol can
CC       be acetylated.
//
ID   2.3.1.70
DE   Deleted entry.
//
ID   2.3.1.71
DE   Glycine N-benzoyltransferase.
CA   Benzoyl-CoA + glycine = CoA + N-benzoylglycine.
CC   -!- Not identical with EC 2.3.1.13 or EC 2.3.1.68.
//
ID   2.3.1.72
DE   Indoleacetylglucose--inositol O-acyltransferase.
CA   1-O-(indol-3-yl)acetyl-beta-D-glucose + myo-inositol = D-glucose +
CA   O-(indol-3-yl)acetyl-myo-inositol.
CC   -!- The position of acylation is indeterminate because of the ease of
CC       acyl transfer between hydroxy groups.
//
ID   2.3.1.73
DE   Diacylglycerol--sterol O-acyltransferase.
CA   1,2-diacyl-sn-glycerol + a sterol = monoacylglycerol + a sterol ester.
CC   -!- Cholesterol, sitosterol, campesterol and diacylglycerol can act as
CC       acceptors.
CC   -!- Transfers a number of long-chain fatty acyl groups.
//
ID   2.3.1.74
DE   Naringenin-chalcone synthase.
AN   6'-deoxychalcone synthase.
AN   Chalcone synthase.
AN   Flavonone synthase.
CA   3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO(2).
CC   -!- In the presence of NADH and a reductase, 6'-deoxychalcone is
CC       produced.
PR   PROSITE; PDOC00403;
DR   P54157, BCSA_BACSU ;  P48386, CHS1_CAMSI ;  Q9ZRR8, CHS1_CASGL ;
DR   Q9SML4, CHS1_CICAR ;  Q9XJ58, CHS1_CITSI ;  Q9ZS41, CHS1_DAUCA ;
DR   P48390, CHS1_GERHY ;  P26018, CHS1_HORVU ;  Q9MB33, CHS1_IPOBA ;
DR   P24824, CHS1_MAIZE ;  P30073, CHS1_MEDSA ;  A2ZEX7, CHS1_ORYSI ;
DR   Q2R3A1, CHS1_ORYSJ ;  Q01286, CHS1_PEA   ;  Q9FSB9, CHS1_RUTGR ;
DR   P53414, CHS1_SECCE ;  P13416, CHS1_SINAL ;  P23418, CHS1_SOLLC ;
DR   Q9XGX2, CHS1_SORBI ;  P24826, CHS1_SOYBN ;  P51083, CHS1_TRISU ;
DR   P48387, CHS2_CAMSI ;  Q9XJ57, CHS2_CITSI ;  Q9ZS40, CHS2_DAUCA ;
DR   Q96562, CHS2_HORVU ;  Q9MB41, CHS2_IPOBA ;  P24825, CHS2_MAIZE ;
DR   P30074, CHS2_MEDSA ;  Q8H4L3, CHS2_ORYSJ ;  Q01287, CHS2_PEA   ;
DR   Q9FSB8, CHS2_RUTGR ;  P53415, CHS2_SECCE ;  P23419, CHS2_SOLLC ;
DR   Q43188, CHS2_SOLTU ;  Q9SBL7, CHS2_SORBI ;  P17957, CHS2_SOYBN ;
DR   P51084, CHS2_TRISU ;  O23729, CHS3_BROFI ;  P48388, CHS3_CAMSI ;
DR   P48392, CHS3_GERHY ;  Q9MB40, CHS3_IPOBA ;  P51077, CHS3_MEDSA ;
DR   O23883, CHS3_PEA   ;  Q9FSB7, CHS3_RUTGR ;  P13417, CHS3_SINAL ;
DR   Q9SBL6, CHS3_SORBI ;  P19168, CHS3_SOYBN ;  P51085, CHS3_TRISU ;
DR   O23730, CHS4_BROFI ;  Q9MB39, CHS4_IPOBA ;  P30075, CHS4_MEDSA ;
DR   O23882, CHS4_PEA   ;  Q9SBL5, CHS4_SORBI ;  P51086, CHS4_TRISU ;
DR   P51078, CHS5_MEDSA ;  O23884, CHS5_PEA   ;  Q9SBL4, CHS5_SORBI ;
DR   P48406, CHS5_SOYBN ;  P51087, CHS5_TRISU ;  Q9MB38, CHS6_IPOBA ;
DR   P51079, CHS6_MEDSA ;  Q01288, CHS6_PEA   ;  Q9SBL3, CHS6_SORBI ;
DR   P30080, CHS6_SOYBN ;  P51088, CHS6_TRISU ;  Q9MB37, CHS7_IPOBA ;
DR   P51080, CHS7_MEDSA ;  Q9M5M0, CHS7_PICMA ;  Q9XGX1, CHS7_SORBI ;
DR   P30081, CHS7_SOYBN ;  O23731, CHS8_BROFI ;  Q9MB36, CHS8_IPOBA ;
DR   P30076, CHS8_MEDSA ;  Q9SB26, CHS9_DAUCA ;  P30077, CHS9_MEDSA ;
DR   P48393, CHSA_IPOCO ;  P48395, CHSA_IPONI ;  P48400, CHSA_IPOPL ;
DR   P48397, CHSA_IPOPU ;  P48401, CHSA_IPOTF ;  P48403, CHSA_IPOTR ;
DR   P51081, CHSA_PEA   ;  P08894, CHSA_PETHY ;  Q41436, CHSA_SOLTU ;
DR   P48394, CHSB_IPOCO ;  P48396, CHSB_IPONI ;  P48398, CHSB_IPOPU ;
DR   P48402, CHSB_IPOTF ;  P48404, CHSB_IPOTR ;  P51082, CHSB_PEA   ;
DR   P22924, CHSB_PETHY ;  Q43163, CHSB_SOLTU ;  P48399, CHSC_IPOPU ;
DR   O22045, CHSD_IPONI ;  P22925, CHSD_PETHY ;  O22046, CHSE_IPONI ;
DR   O22047, CHSE_IPOPU ;  P22926, CHSF_PETHY ;  P22927, CHSG_PETHY ;
DR   P22928, CHSJ_PETHY ;  P06515, CHSY_ANTMA ;  Q9SEP4, CHSY_ARAAL ;
DR   P13114, CHSY_ARATH ;  P51075, CHSY_BETPN ;  P48385, CHSY_CALCH ;
DR   Q9SEP2, CHSY_CARAN ;  Q9ZRS4, CHSY_CATRO ;  O04220, CHSY_CHRAE ;
DR   P48389, CHSY_DIACA ;  Q9LKP7, CHSY_DIAMO ;  Q9MBB1, CHSY_EQUAR ;
DR   P51076, CHSY_FRAAN ;  O82144, CHSY_HYDMC ;  Q9FUB7, CHSY_HYPAN ;
DR   P30078, CHSY_MALDO ;  P17818, CHSY_MATIN ;  O22586, CHSY_ONOVI ;
DR   Q9ZU06, CHSY_PERAE ;  O04111, CHSY_PERFR ;  P16107, CHSY_PETCR ;
DR   P49440, CHSY_PHAVU ;  O65872, CHSY_PINST ;  P30079, CHSY_PINSY ;
DR   P23569, CHSY_PUEML ;  O22652, CHSY_RAPSA ;  P51089, CHSY_VIGUN ;
DR   P51090, CHSY_VITVI ;  Q55E72, PKS1_DICDI ;  Q54FI3, PKS37_DICDI;
//
ID   2.3.1.75
DE   Long-chain-alcohol O-fatty-acyltransferase.
AN   Wax synthase.
CA   Acyl-CoA + a long-chain alcohol = CoA + a long-chain ester.
CC   -!- Transfers saturated or unsaturated acyl residues of chain length
CC       C(18) to C(20) to long-chain alcohols, forming waxes.
CC   -!- The best acceptor is cis-icos-11-en-1-ol.
DR   Q58HT5, AWAT1_HUMAN;  A2ADU9, AWAT1_MOUSE;  Q6E213, AWAT2_HUMAN;
DR   Q6E1M8, AWAT2_MOUSE;  P67210, TGS2_MYCTU ;  Q9FJ72, WAXS1_ARATH;
DR   Q9XGY6, WAXS1_SIMCH;  Q9FJ73, WAXS2_ARATH;  Q9FJ74, WAXS3_ARATH;
DR   Q9FJ75, WAXS4_ARATH;  Q9FJ76, WAXS5_ARATH;  Q9FJ77, WAXS6_ARATH;
DR   Q9FJ78, WAXS7_ARATH;  Q9LNL1, WAXS8_ARATH;  Q4PT07, WAXS9_ARATH;
DR   Q3ED15, WAXSA_ARATH;  Q9FGN1, WAXSB_ARATH;  Q93ZR6, WSD1_ARATH ;
DR   Q8GGG1, WSD_ACIAD  ;
//
ID   2.3.1.76
DE   Retinol O-fatty-acyltransferase.
CA   Acyl-CoA + retinol = CoA + retinyl ester.
CC   -!- Acts on palmitoyl-CoA and other long-chain fatty-acyl derivatives of
CC       CoA.
//
ID   2.3.1.77
DE   Triacylglycerol--sterol O-acyltransferase.
CA   Triacylglycerol + a 3-beta-hydroxysterol = diacylglycerol + a 3-beta-
CA   hydroxysterol ester.
CC   -!- Tripalmitoylglycerol can act as donor, and, more slowly, other
CC       triacylglycerols containing C(6) to C(22) fatty acids.
CC   -!- The best acceptors are 3-beta-hydroxysterols with a planar ring
CC       system.
//
ID   2.3.1.78
DE   Heparan-alpha-glucosaminide N-acetyltransferase.
CA   Acetyl-CoA + heparan sulfate alpha-D-glucosaminide = CoA + heparan
CA   sulfate N-acetyl-alpha-D-glucosaminide.
CC   -!- Brings about the acetylation of glucosamine groups of heparan sulfate
CC       and heparin from which the sulfate has been removed.
CC   -!- Also acts on heparin.
CC   -!- Not identical with EC 2.3.1.3 or EC 2.3.1.4.
DR   Q68CP4, HGNAT_HUMAN;  Q3UDW8, HGNAT_MOUSE;
//
ID   2.3.1.79
DE   Maltose O-acetyltransferase.
CA   Acetyl-CoA + maltose = CoA + acetyl-maltose.
CC   -!- Not identical with EC 2.3.1.18.
PR   PROSITE; PDOC00094;
DR   P37515, MAA_BACSU  ;  P77791, MAA_ECOLI  ;
//
ID   2.3.1.80
DE   Cysteine-S-conjugate N-acetyltransferase.
CA   Acetyl-CoA + an S-substituted L-cysteine = CoA + an S-substituted
CA   N-acetyl-L-cysteine.
CC   -!- S-benzyl-L-cysteine can act as acceptor, and, in decreasing order of
CC       activity, S-butyl-L-cysteine, S-propyl-L-cysteine, O-benzyl-L-serine
CC       and S-ethyl-L-cysteine.
//
ID   2.3.1.81
DE   Aminoglycoside N(3')-acetyltransferase.
AN   Gentamicin-(3)-N-acetyltransferase.
CA   Acetyl-CoA + a 2-deoxystreptamine antibiotic = CoA + N(3')-acetyl-2-
CA   deoxystreptamine antibiotic.
CC   -!- A wide range of antibiotics containing the 2-deoxystreptamine ring
CC       can act as acceptor, including gentamicin, kanamycin, tobramycin,
CC       neomycin and apramycin.
CC   -!- Different from EC 2.3.1.60.
DR   P13246, AAC31_SALSP;  P0A255, AAC32_SALSP;  Q01515, AAC3_SERMA ;
DR   P29807, AACC2_ACIBA;  P0A256, AACC3_ENTCL;  P29808, AACC3_PSEAE;
DR   P08988, AACC4_SALSP;  P30180, AACC7_STRRY;  P29809, AACC8_STRFR;
DR   P29810, AACC9_MICCH;
//
ID   2.3.1.82
DE   Aminoglycoside N(6')-acetyltransferase.
AN   6'-aminoglycoside-N-acetyltransferase.
AN   AAC(6').
AN   Kanamycin 6'-N-acetyltransferase.
CA   Acetyl-CoA + kanamycin-B = CoA + N(6')-acetylkanamycin-B.
CC   -!- The antibiotics kanamycin A, kanamycin B, neomycin, gentamicin C(1a),
CC       gentamicin C(2), sisomicin and tobramycin are substrates.
CC   -!- The antibiotic paromomycin is not a substrate.
CC   -!- The 6-amino group of the purpurosamine ring is acetylated.
CC   -!- Formerly EC 2.3.1.55.
DR   P10051, AAC6_CITDI ;  P50858, AAC6_ENTAE ;  P19650, AAC6_KLEPN ;
DR   P20092, AAC6_SERMA ;
//
ID   2.3.1.83
DE   Phosphatidylcholine--dolichol O-acyltransferase.
CA   3-sn-phosphatidylcholine + dolichol = 1-acyl-sn-glycero-3-phosphocholine
CA   + acyldolichol.
//
ID   2.3.1.84
DE   Alcohol O-acetyltransferase.
AN   AATASE.
CA   Acetyl-CoA + an alcohol = CoA + an acetyl ester.
CC   -!- Acts on a range of short-chain aliphatic alcohols, including methanol
CC       and ethanol.
DR   P40353, ATF1_YEAST ;  P53296, ATF2_YEAST ;  Q02891, MCFS1_YEAST;
DR   P38295, MCFS2_YEAST;
//
ID   2.3.1.85
DE   Fatty-acid synthase.
CA   Acetyl-CoA + n malonyl-CoA + 2n NADPH = a long-chain fatty acid + (n+1)
CA   CoA + n CO(2) + 2n NADP(+).
CC   -!- The animal enzyme is a multifunctional protein catalyzing the
CC       reactions of EC 2.3.1.38, EC 2.3.1.39, EC 2.3.1.41, EC 1.1.1.100,
CC       EC 4.2.1.61, EC 1.3.1.10 and EC 3.1.2.14.
DR   P36189, FAS_ANSAN  ;  Q71SP7, FAS_BOVIN  ;  P08757, FAS_CAPHI  ;
DR   P12276, FAS_CHICK  ;  P49327, FAS_HUMAN  ;  P19096, FAS_MOUSE  ;
DR   P07855, FAS_RABIT  ;  P12785, FAS_RAT    ;
//
ID   2.3.1.86
DE   Fatty-acyl-CoA synthase.
AN   Yeast fatty acid synthase.
CA   Acetyl-CoA + n malonyl-CoA + 2n NADH + 2n NADPH = long-chain-acyl-CoA +
CA   n CoA + n CO(2) + 2n NAD(+) + 2n NADP(+).
CC   -!- The Saccharomyces cerevisiae enzyme is a multi-functional protein
CC       catalyzing the reactions of EC 2.3.1.38, EC 2.3.1.39, EC 2.3.1.41,
CC       EC 1.1.1.100, EC 1.1.1.279, EC 4.2.1.61 and EC 1.3.1.9.
DR   P34731, FAS1_CANAL ;  Q9UUG0, FAS1_SCHPO ;  P34229, FAS1_YARLI ;
DR   P07149, FAS1_YEAST ;  P43098, FAS2_CANAL ;  P15368, FAS2_PENPA ;
DR   Q10289, FAS2_SCHPO ;  P19097, FAS2_YEAST ;
//
ID   2.3.1.87
DE   Aralkylamine N-acetyltransferase.
AN   AANAT.
AN   Arylalkylamine N-acetyltransferase.
AN   Melatonin rhythm enzyme.
AN   Serotonin acetylase.
AN   Serotonin acetyltransferase.
AN   Serotonin N-acetyltransferase.
CA   Acetyl-CoA + a 2-arylethylamine = CoA + an N-acetyl-2-arylethylamine.
CC   -!- Narrow specificity toward 2-arylethylamines, including serotonin
CC       (5-hydroxytryptamine), tryptamine, 5-methoxytryptamine and
CC       phenylethylamine.
CC   -!- This is the penultimate enzyme in the production of melatonin
CC       (5-methoxy-N-acetyltryptamine) and controls its synthesis (cf.
CC       EC 2.1.1.4).
CC   -!- Differs from EC 2.3.1.5.
DR   O02785, SNAT_BOVIN ;  P79774, SNAT_CHICK ;  Q16613, SNAT_HUMAN ;
DR   O97756, SNAT_MACMU ;  Q9R0A9, SNAT_MESAU ;  O88816, SNAT_MOUSE ;
DR   Q5IS55, SNAT_PANTR ;  Q64666, SNAT_RAT   ;  Q29495, SNAT_SHEEP ;
//
ID   2.3.1.88
DE   Peptide alpha-N-acetyltransferase.
AN   Amino-terminal amino acid-acetylating enzyme.
AN   Beta-endorphin acetyltransferase.
AN   N(alpha)-acetyltransferase.
AN   NAT.
AN   Peptide acetyltransferase.
AN   Protein N-terminal acetyltransferase.
CA   Acetyl-CoA + peptide = N(alpha)-acetylpeptide + CoA.
CC   -!- Acetylates N-terminal alanine, serine, methionine and glutamate
CC       residues in a number of peptides and proteins, including beta-
CC       endorphin, corticotropins and melanotropin (cf. EC 2.3.1.108).
DR   Q9UTI3, ARD1_SCHPO ;  P07347, ARD1_YEAST ;  Q2KI14, NAA10_BOVIN;
DR   P41227, NAA10_HUMAN;  Q9QY36, NAA10_MOUSE;  Q9BSU3, NAA11_HUMAN;
DR   Q3UX61, NAA11_MOUSE;  Q4V8K3, NAA11_RAT  ;  Q58ED9, NAA20_DANRE;
DR   P61599, NAA20_HUMAN;  Q2PFM2, NAA20_MACFA;  P61600, NAA20_MOUSE;
DR   Q7ZXR3, NAA20_XENLA;  Q6P632, NAA20_XENTR;  Q147X3, NAA30_HUMAN;
DR   Q8CES0, NAA30_MOUSE;  O74311, NAA30_SCHPO;  Q03503, NAA30_YEAST;
DR   P37293, NAT2_YEAST ;  Q06504, NAT3_YEAST ;
//
ID   2.3.1.89
DE   Tetrahydrodipicolinate N-acetyltransferase.
AN   Tetrahydrodipicolinate acetylase.
CA   Acetyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H(2)O =
CA   CoA + L-2-acetamido-6-oxoheptanedioate.
DR   A6TT15, DAPH_ALKMQ ;  B7GIC1, DAPH_ANOFW ;  A7Z432, DAPH_BACA2 ;
DR   C3P6Y8, DAPH_BACAA ;  C3LI47, DAPH_BACAC ;  A0RHZ3, DAPH_BACAH ;
DR   Q81MQ2, DAPH_BACAN ;  B7JKV5, DAPH_BACC0 ;  Q731Y5, DAPH_BACC1 ;
DR   B7IVL8, DAPH_BACC2 ;  C1EPZ5, DAPH_BACC3 ;  B7H6W8, DAPH_BACC4 ;
DR   B7HMV2, DAPH_BACC7 ;  A7GS09, DAPH_BACCN ;  B9IW61, DAPH_BACCQ ;
DR   Q819J5, DAPH_BACCR ;  Q635U7, DAPH_BACCZ ;  Q9K9H8, DAPH_BACHD ;
DR   Q6HEI4, DAPH_BACHK ;  Q65K85, DAPH_BACLD ;  A8FCN1, DAPH_BACP2 ;
DR   Q5WF92, DAPH_BACSK ;  O34981, DAPH_BACSU ;  A9VUE3, DAPH_BACWK ;
DR   C0ZGH9, DAPH_BREBN ;  Q97GI6, DAPH_CLOAB ;  A7FYA5, DAPH_CLOB1 ;
DR   C3KTL7, DAPH_CLOB6 ;  A6LUD2, DAPH_CLOB8 ;  B2V5B7, DAPH_CLOBA ;
DR   B2TS78, DAPH_CLOBB ;  A5I6N5, DAPH_CLOBH ;  C1FL32, DAPH_CLOBJ ;
DR   B1IMX1, DAPH_CLOBK ;  A7GI22, DAPH_CLOBL ;  B1L0V4, DAPH_CLOBM ;
DR   Q17ZX2, DAPH_CLOD6 ;  A0PZL5, DAPH_CLONN ;  Q0TP51, DAPH_CLOP1 ;
DR   Q8XJ52, DAPH_CLOPE ;  Q0SRS1, DAPH_CLOPS ;  Q836H8, DAPH_ENTFA ;
DR   B1YJ41, DAPH_EXIS2 ;  C4L2D4, DAPH_EXISA ;  A7HJ58, DAPH_FERNB ;
DR   Q5L146, DAPH_GEOKA ;  C5D826, DAPH_GEOSW ;  A4ILT5, DAPH_GEOTN ;
DR   C5CHX7, DAPH_KOSOT ;  Q5FKR1, DAPH_LACAC ;  Q03CW1, DAPH_LACC3 ;
DR   B3W7E7, DAPH_LACCB ;  B2GC09, DAPH_LACF3 ;  A8YUT1, DAPH_LACH4 ;
DR   Q9CIS5, DAPH_LACLA ;  A2RI05, DAPH_LACLM ;  Q032G9, DAPH_LACLS ;
DR   Q88V23, DAPH_LACPL ;  A5VJ56, DAPH_LACRD ;  B2G6M7, DAPH_LACRJ ;
DR   Q1WUQ8, DAPH_LACS1 ;  B1MZN0, DAPH_LEUCK ;  Q03YE4, DAPH_LEUMM ;
DR   Q92D11, DAPH_LISIN ;  Q6LAN4, DAPH_LISIV ;  C1L1T2, DAPH_LISMC ;
DR   Q721F5, DAPH_LISMF ;  B8DEC4, DAPH_LISMH ;  Q8Y8A1, DAPH_LISMO ;
DR   A0AHD1, DAPH_LISW6 ;  Q8TY70, DAPH_METKA ;  Q8ERA4, DAPH_OCEIH ;
DR   Q04FS3, DAPH_OENOB ;  Q03HT0, DAPH_PEDPA ;  A9BHR6, DAPH_PETMO ;
DR   A7X274, DAPH_STAA1 ;  A6U1L8, DAPH_STAA2 ;  Q2FH41, DAPH_STAA3 ;
DR   Q2FYN7, DAPH_STAA8 ;  A5ISS9, DAPH_STAA9 ;  Q2YXZ7, DAPH_STAAB ;
DR   Q5HG23, DAPH_STAAC ;  A6QGU8, DAPH_STAAE ;  Q7A2S0, DAPH_STAAM ;
DR   Q7A5P7, DAPH_STAAN ;  Q6GH11, DAPH_STAAR ;  Q6G9G4, DAPH_STAAS ;
DR   A8Z3X5, DAPH_STAAT ;  Q9EZ10, DAPH_STAAU ;  Q7A0X6, DAPH_STAAW ;
DR   B9DP25, DAPH_STACT ;  Q5HPE5, DAPH_STAEQ ;  Q8CSM7, DAPH_STAES ;
DR   Q4L6A2, DAPH_STAHJ ;  Q49XJ9, DAPH_STAS1 ;  A8AUL9, DAPH_STRGC ;
DR   Q8DVY7, DAPH_STRMU ;  Q04I77, DAPH_STRP2 ;  B5E3A4, DAPH_STRP4 ;
DR   C1CAS4, DAPH_STRP7 ;  B1I9G3, DAPH_STRPI ;  B8ZPL9, DAPH_STRPJ ;
DR   Q97NE6, DAPH_STRPN ;  B2IN15, DAPH_STRPS ;  Q8DN54, DAPH_STRR6 ;
DR   A4W4B5, DAPH_STRS2 ;  A3CQT5, DAPH_STRSV ;  A4VY24, DAPH_STRSY ;
DR   Q5LXY2, DAPH_STRT1 ;  Q5M2I4, DAPH_STRT2 ;  Q03IN0, DAPH_STRTD ;
DR   B9DVY7, DAPH_STRU0 ;  C1CH25, DAPH_STRZJ ;  C1CN43, DAPH_STRZP ;
DR   C1CU00, DAPH_STRZT ;  B7IF15, DAPH_THEAB ;  A8F8L8, DAPH_THELT ;
DR   A6LP60, DAPH_THEM4 ;  Q9X1K7, DAPH_THEMA ;  B9K867, DAPH_THENN ;
DR   A5IM64, DAPH_THEP1 ;  B0KAL9, DAPH_THEP3 ;  B0K4I5, DAPH_THEPX ;
DR   B1LBQ9, DAPH_THESQ ;  Q8RBI7, DAPH_THETN ;
//
ID   2.3.1.90
DE   Beta-glucogallin O-galloyltransferase.
CA   2 1-O-galloyl-beta-D-glucose = D-glucose + 1-O,6-O-digalloyl-beta-D-
CA   glucose.
CC   -!- Beta-glucogallin can act as donor and as acceptor.
CC   -!- Digalloylglucose can also act as acceptor, with the formation of
CC       1-O,2-O,6-O-trigalloylglucose.
//
ID   2.3.1.91
DE   Sinapoylglucose--choline O-sinapoyltransferase.
AN   Sinapine synthase.
CA   1-O-sinapoyl-beta-D-glucose + choline = D-glucose + sinapoylcholine.
DR   Q8VZU3, SCP19_ARATH;
//
ID   2.3.1.92
DE   Sinapoylglucose--malate O-sinapoyltransferase.
CA   1-O-sinapoyl-beta-D-glucose + (S)-malate = D-glucose + sinapoyl-(S)-
CA   malate.
DR   Q8RUW5, SCP8_ARATH ;
//
ID   2.3.1.93
DE   13-hydroxylupanine O-tigloyltransferase.
CA   (E)-2-methylcrotonoyl-CoA + 13-hydroxylupanine = CoA + 13-((E)-2-
CA   methylcrotonoyl)oxylupanine.
CC   -!- Benzoyl-CoA and, more slowly, pentanoyl-CoA, 3-methylbutanoyl-CoA and
CC       butanoyl-CoA can act as acyl donors.
CC   -!- Involved in the synthesis of lupanine alkaloids.
DR   Q5H873, HLTT_LUPAL ;
//
ID   2.3.1.94
DE   6-deoxyerythronolide-B synthase.
AN   6-deoxyerythronolide B synthase.
AN   DEBS.
AN   Deoxyerythronolide B synthase.
AN   Erythronolide synthase.
AN   Erythronolide-condensing enzyme.
CA   Propanoyl-CoA + 6 (2S)-methylmalonyl-CoA + 6 NADPH = 6-deoxyerythronolide
CA   B + 7 CoA + 6 CO(2) + H(2)O + 6 NADP(+).
CC   -!- The product, 6-deoxyerythronolide B, contains a 14-membered lactone
CC       ring and is an intermediate in the biosynthesis of erythromycin
CC       antibiotics.
CC   -!- Biosynthesis of 6-deoxyerythronolide B requires 28 active sites that
CC       are precisely arranged along three large polypeptides, denoted DEBS1,
CC       -2 and -3.
CC   -!- The polyketide product is synthesized by the processive action of a
CC       loading didomain, six extension modules and a terminal thioesterase
CC       domain.
CC   -!- Each extension module contains a minimum of a ketosynthase (KS),
CC       an acyltransferase (AT) and an acyl-carrier protein (ACP).
CC   -!- The KS domain both accepts the growing polyketide chain from the
CC       previous module and catalyzes the subsequent decarboxylative
CC       condensation between this substrate and an ACP-bound methylmalonyl
CC       extender unit, introduce by the AT domain.
CC   -!- This combined effort gives rise to a new polyketide intermediate that
CC       has been extended by two carbon atoms.
DR   Q03131, ERYA1_SACER;  Q03132, ERYA2_SACER;  Q03133, ERYA3_SACER;
//
ID   2.3.1.95
DE   Trihydroxystilbene synthase.
AN   Resveratrol synthase.
AN   Stilbene synthase.
CA   3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + 3,4',5-trihydroxy-stilbene +
CA   4 CO(2).
CC   -!- Not identical with EC 2.3.1.74 or EC 2.3.1.146.
PR   PROSITE; PDOC00403;
DR   P20178, THS1_ARAHY ;  P28343, THS1_VITVI ;  P20077, THS2_ARAHY ;
DR   P51070, THS2_VITVI ;  P51069, THS3_ARAHY ;  P51071, THS3_VITVI ;
DR   A5AEM3, THS4_VITVI ;  A5C9M2, THS5_VITVI ;  A2ICC6, THS7_VITVI ;
//
ID   2.3.1.96
DE   Glycoprotein N-palmitoyltransferase.
CA   Palmitoyl-CoA + glycoprotein = CoA + N-palmitoylglycoprotein.
CC   -!- Acts on glycoprotein from mucus.
CC   -!- Activated by 1,4-dithiothreitol.
//
ID   2.3.1.97
DE   Glycylpeptide N-tetradecanoyltransferase.
AN   Peptide N-myristoyltransferase.
AN   Peptide N-tetradecanoyltransferase.
CA   Tetradecanoyl-CoA + glycylpeptide = CoA + N-tetradecanoylglycylpeptide.
CC   -!- The enzyme from Saccharomyces cerevisiae is highly specific for
CC       tetradecanoyl-CoA, and for N-terminal glycine in oligopeptides
CC       containing serine in the 5-position.
CC   -!- The enzyme from mammalian heart transfers acyl groups to a specific
CC       acceptor protein of 51 kDa.
PR   PROSITE; PDOC00752;
DR   Q9LTR9, NMT1_ARATH ;  P31717, NMT1_BOVIN ;  P30419, NMT1_HUMAN ;
DR   O70310, NMT1_MOUSE ;  Q5RAF3, NMT1_PONAB ;  Q8K1Q0, NMT1_RAT   ;
DR   Q94L32, NMT2_ARATH ;  Q9N181, NMT2_BOVIN ;  O60551, NMT2_HUMAN ;
DR   O70311, NMT2_MOUSE ;  P34763, NMT_AJECA  ;  Q9EMI7, NMT_AMEPV  ;
DR   Q75EK2, NMT_ASHGO  ;  Q9UVX3, NMT_ASPFU  ;  P46548, NMT_CAEEL  ;
DR   P30418, NMT_CANAL  ;  O74234, NMT_CANGA  ;  P0CP21, NMT_CRYNB  ;
DR   P0CP20, NMT_CRYNJ  ;  P34809, NMT_CRYNV  ;  Q6BJF4, NMT_DEBHA  ;
DR   Q553B6, NMT_DICDI  ;  O61613, NMT_DROME  ;  Q8TFN1, NMT_EMENI  ;
DR   Q4I061, NMT_GIBZE  ;  Q6CMK4, NMT_KLULA  ;  Q5UR64, NMT_MIMIV  ;
DR   Q9YW20, NMT_MSEPV  ;  Q7S3C8, NMT_NEUCR  ;  Q8ILW6, NMT_PLAF7  ;
DR   O43010, NMT_SCHPO  ;  Q4PB56, NMT_USTMA  ;  Q6C7G2, NMT_YARLI  ;
DR   P14743, NMT_YEAST  ;
//
ID   2.3.1.98
DE   Chlorogenate--glucarate O-hydroxycinnamoyltransferase.
CA   Chlorogenate + glucarate = quinate + 2-O-caffeoylglucarate.
CC   -!- Galactarate can act as acceptor, more slowly.
CC   -!- Involved with EC 2.3.1.99 in the formation of caffeoylglucarate in
CC       tomato.
//
ID   2.3.1.99
DE   Quinate O-hydroxycinnamoyltransferase.
AN   Hydroxycinnamoyl coenzyme A-quinate transferase.
CA   Feruloyl-CoA + quinate = CoA + O-feruloylquinate.
CC   -!- Caffeoyl-CoA and 4-coumaroyl-CoA can also act as donors, more slowly.
CC   -!- Involved in the biosynthesis of chlorogenic acid in sweet potato and,
CC       with EC 2.3.1.98 in the formation of caffeoyl-CoA in tomato.
//
ID   2.3.1.100
DE   [Myelin-proteolipid] O-palmitoyltransferase.
AN   Acyl-protein synthase.
AN   Myelin PLP acyltransferase.
CA   Palmitoyl-CoA + [myelin proteolipid] = CoA + O-palmitoyl-[myelin
CA   proteolipid].
CC   -!- The enzyme in brain transfers long-chain acyl residues to the
CC       endogenous myelin proteolipid.
//
ID   2.3.1.101
DE   Formylmethanofuran--tetrahydromethanopterin N-formyltransferase.
CA   Formylmethanofuran + 5,6,7,8-tetrahydromethanopterin = methanofuran +
CA   5-formyl-5,6,7,8-tetrahydromethanopterin.
CC   -!- Methanofuran is a complex 4-substituted furfurylamine and is involved
CC       in the formation of methane from CO(2) in Methanobacterium
CC       thermoautotrophicum.
CC   -!- Formerly EC 3.1.1.12.
DR   O28076, FTR_ARCFU  ;  Q8TUQ5, FTR_METAC  ;  P55301, FTR_METBF  ;
DR   Q12VA6, FTR_METBU  ;  Q9ADT1, FTR_METCA  ;  Q49118, FTR_METEA  ;
DR   Q1H0Q5, FTR_METFK  ;  Q49168, FTR_METFV  ;  Q57766, FTR_METJA  ;
DR   Q49610, FTR_METKA  ;  Q8PXA1, FTR_METMA  ;  P21348, FTR_METTH  ;
DR   Q7UKZ8, FTR_RHOBA  ;
//
ID   2.3.1.102
DE   N(6)-hydroxylysine O-acetyltransferase.
AN   N(6)-hydroxylysine acetylase.
CA   Acetyl-CoA + N(6)-hydroxy-L-lysine = CoA + N(6)-acetyl-N(6)-hydroxy-L-
CA   lysine.
CC   -!- Involved in the synthesis of aerobactin from lysine in a strain of
CC       Escherichia coli.
//
ID   2.3.1.103
DE   Sinapoylglucose--sinapoylglucose O-sinapoyltransferase.
CA   2 1-O-sinapoyl beta-D-glucoside = D-glucose + 1,2-bis-O-sinapoyl beta-D-
CA   glucoside.
//
ID   2.3.1.104
DE   1-alkenylglycerophosphocholine O-acyltransferase.
CA   Acyl-CoA + 1-alkenylglycerophosphocholine = CoA + 1-alkenyl-2-
CA   acylglycerophosphocholine.
CC   -!- Not identical with EC 2.3.1.121.
//
ID   2.3.1.105
DE   Alkylglycerophosphate 2-O-acetyltransferase.
CA   Acetyl-CoA + 1-alkyl-sn-glycero-3-phosphate = CoA + 1-alkyl-2-acetyl-
CA   sn-glycero-3-phosphate.
CC   -!- Involved in the biosynthesis of thrombocyte activating factor in
CC       animal tissues.
//
ID   2.3.1.106
DE   Tartronate O-hydroxycinnamoyltransferase.
AN   Hydroxycinnamoyl-coenzyme-A:tartronate hydroxycinnamoyltransferase.
AN   Tartronate sinapoyltransferase.
CA   Sinapoyl-CoA + 2-hydroxymalonate = CoA + sinapoyltartronate.
CC   -!- 4-coumaroyl-CoA (4-hydroxycinnamoyl-CoA), caffeoyl-CoA (3,4-
CC       dihydroxycinnamoyl-CoA) and feruloyl-CoA (4-hydroxy-3-
CC       methoxycinnamoyl-CoA) can also act as donors for the enzyme from the
CC       mung bean (Vigna radiata).
//
ID   2.3.1.107
DE   Deacetylvindoline O-acetyltransferase.
AN   17-O-deacetylvindoline O-acetyltransferase.
AN   17-O-deacetylvindoline-17-O-acetyltransferase.
AN   Acetyl-CoA-17-O-deacetylvindoline 17-O-acetyltransferase.
AN   Acetyl-CoA:17-O-deacetylvindoline 17-O-acetyltransferase.
AN   Acetylcoenzyme A-deacetylvindoline 4-O-acetyltransferase.
AN   Acetylcoenzyme A:deacetylvindoline 4-O-acetyltransferase.
AN   Acetylcoenzyme A:deacetylvindoline O-acetyltransferase.
AN   DAT.
AN   Deacetylvindoline acetyltransferase.
CA   Acetyl-CoA + deacetylvindoline = CoA + vindoline.
CC   -!- Catalyzes the final step in the biosynthesis of vindoline from
CC       tabersonine in the Madagascar periwinkle, Catharanthus roseus.
DR   Q9ZTK5, DAT_CATRO  ;
//
ID   2.3.1.108
DE   Alpha-tubulin N-acetyltransferase.
AN   Alpha-tubulin acetylase.
AN   Alpha-tubulin acetyltransferase.
AN   TAT.
AN   Tubulin acetyltransferase.
AN   Tubulin N-acetyltransferase.
CA   Acetyl-CoA + [alpha-tubulin]-L-lysine = CoA + [alpha-tubulin]-N(6)-
CA   acetyl-L-lysine.
CC   -!- The enzyme from Chlamydomonas flagella also acetylates mammalian
CC       brain alpha-tubulin.
DR   A8XRF5, ATAT1_CAEBR;  O45100, ATAT1_CAEEL;  Q9VSY4, ATAT1_DROME;
DR   Q4CQJ5, ATAT1_TRYCR;  A8XKM2, ATAT2_CAEBR;  Q23192, ATAT2_CAEEL;
DR   Q9W5X9, ATAT2_DROME;  Q4DTX9, ATAT2_TRYCR;  Q16Y34, ATAT_AEDAE ;
DR   Q7PNM6, ATAT_ANOGA ;  Q58CX6, ATAT_BOVIN ;  B0W3R7, ATAT_CULQU ;
DR   Q6PH17, ATAT_DANRE ;  A8BM50, ATAT_GIAIC ;  Q5SQI0, ATAT_HUMAN ;
DR   A4HE59, ATAT_LEIBR ;  A4I1F7, ATAT_LEIIN ;  Q4Q9X8, ATAT_LEIMA ;
DR   Q5TM63, ATAT_MACMU ;  Q8K341, ATAT_MOUSE ;  D0NK82, ATAT_PHYIN ;
DR   Q767K7, ATAT_PIG   ;  C0H559, ATAT_PLAF7 ;  B3L2R5, ATAT_PLAKH ;
DR   A5K6W4, ATAT_PLAVI ;  Q6MG11, ATAT_RAT   ;  Q5DD96, ATAT_SCHJA ;
DR   Q22XZ3, ATAT_TETTH ;  B3RNE8, ATAT_TRIAD ;  Q57XX3, ATAT_TRYB2 ;
DR   Q5FWM1, ATAT_XENLA ;  B2RZF9, ATAT_XENTR ;
//
ID   2.3.1.109
DE   Arginine N-succinyltransferase.
AN   AOST.
AN   Arginine and ornithine N(2)-succinyltransferase.
AN   Arginine succinyltransferase.
AN   AST.
CA   Succinyl-CoA + L-arginine = CoA + N(2)-succinyl-L-arginine.
CC   -!- Also acts on L-ornithine.
CC   -!- This is the first enzyme in the arginine succinyltransferase (AST)
CC       pathway for the catabolism of arginine.
CC   -!- This pathway converts the carbon skeleton of arginine into glutamate,
CC       with the concomitant production of ammonia and conversion of
CC       succinyl-CoA into succinate and CoA.
CC   -!- The five enzymes involved in this pathway are EC 2.3.1.109,
CC       EC 3.5.3.23, EC 2.6.1.81, EC 1.2.1.71 and EC 3.5.1.96.
DR   A8AHD9, ASTA_CITK8 ;  A7ZML5, ASTA_ECO24 ;  B7USC8, ASTA_ECO27 ;
DR   B7MAV8, ASTA_ECO45 ;  B7L6M1, ASTA_ECO55 ;  P0AE38, ASTA_ECO57 ;
DR   B5YQ34, ASTA_ECO5E ;  B7NT30, ASTA_ECO7I ;  B7MVM6, ASTA_ECO81 ;
DR   B7M1F9, ASTA_ECO8A ;  C4ZZA3, ASTA_ECOBW ;  B1XGK8, ASTA_ECODH ;
DR   A8A0T9, ASTA_ECOHS ;  A1ABS8, ASTA_ECOK1 ;  Q0TH83, ASTA_ECOL5 ;
DR   Q8FH00, ASTA_ECOL6 ;  B1IPI3, ASTA_ECOLC ;  P0AE37, ASTA_ECOLI ;
DR   B7N583, ASTA_ECOLU ;  B6IBG7, ASTA_ECOSE ;  B1LDY4, ASTA_ECOSM ;
DR   Q1RB46, ASTA_ECOUT ;  A4W9J6, ASTA_ENT38 ;  B7LQ45, ASTA_ESCF3 ;
DR   Q7N2G8, ASTA_PHOLL ;  P80357, ASTA_PSEAE ;  B5F845, ASTA_SALA4 ;
DR   A9MFG1, ASTA_SALAR ;  B5FJD7, ASTA_SALDC ;  B5QWI9, ASTA_SALEP ;
DR   B4TGE1, ASTA_SALHS ;  B4T3Z5, ASTA_SALNS ;  Q5PHB9, ASTA_SALPA ;
DR   A9N277, ASTA_SALPB ;  B5BA71, ASTA_SALPK ;  B4TUC2, ASTA_SALSV ;
DR   Q8Z6G0, ASTA_SALTI ;  Q8ZPV1, ASTA_SALTY ;  B2U3C9, ASTA_SHIB3 ;
DR   Q321N9, ASTA_SHIBS ;  Q32G89, ASTA_SHIDS ;  Q0T4V4, ASTA_SHIF8 ;
DR   Q83L52, ASTA_SHIFL ;  Q3Z294, ASTA_SHISS ;  A1JS43, ASTA_YERE8 ;
DR   Q1C8B0, ASTA_YERPA ;  B2K295, ASTA_YERPB ;  Q9ZC67, ASTA_YERPE ;
DR   A9QZ62, ASTA_YERPG ;  A4TJU6, ASTA_YERPP ;  Q66B20, ASTA_YERPS ;
DR   B1JMD2, ASTA_YERPY ;  P80358, ASTG_PSEAE ;
//
ID   2.3.1.110
DE   Tyramine N-feruloyltransferase.
CA   Feruloyl-CoA + tyramine = CoA + N-feruloyltyramine.
CC   -!- Cinnamoyl-CoA, 4-coumaroyl-CoA and sinapoyl-CoA can also act as
CC       donors.
CC   -!- Some aromatic amines can act as acceptors.
DR   P80969, THT10_TOBAC;  Q9SMB8, THT11_TOBAC;
//
ID   2.3.1.111
DE   Mycocerosate synthase.
CA   Acyl-CoA + n methylmalonyl-CoA + 2n NADPH = multi-methyl-branched acyl-
CA   CoA + n CoA + n CO(2) + 2n NADP(+).
CC   -!- Elongates CoA esters of fatty acids from C(6) to C(20) by
CC       incorporation of methylmalonyl, but not malonyl, residues, to form
CC       multimethyl-branched fatty-acyl-CoA such as 2,4,6,8-tetramethyl-
CC       octosanoyl-CoA.
PR   PROSITE; PDOC00529;
DR   Q02251, MCAS_MYCBO ;
//
ID   2.3.1.112
DE   D-tryptophan N-malonyltransferase.
CA   Malonyl-CoA + D-tryptophan = CoA + N(2)-malonyl-D-tryptophan.
CC   -!- 1-aminocyclopropane-1-carboxylate can act instead of malonyl-CoA.
//
ID   2.3.1.113
DE   Anthranilate N-malonyltransferase.
CA   Malonyl-CoA + anthranilate = CoA + N-malonylanthranilate.
//
ID   2.3.1.114
DE   3,4-dichloroaniline N-malonyltransferase.
CA   Malonyl-CoA + 3,4-dichloroaniline = CoA + N-(3,4-dichlorophenyl)-
CA   malonamate.
//
ID   2.3.1.115
DE   Isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase.
AN   Flavone/flavonol 7-O-beta-D-glucoside malonyltransferase.
CA   Malonyl-CoA + biochanin A 7-O-beta-D-glucoside = CoA + biochanin A 7-O-
CA   (6-O-malonyl-beta-D-glucoside).
CC   -!- The 6-position of the glucose residue of formononetin can also act as
CC       acceptor; some other 7-O-glucosides of isoflavones, flavones and
CC       flavonols can also act, but more slowly.
//
ID   2.3.1.116
DE   Flavonol-3-O-beta-glucoside O-malonyltransferase.
CA   Malonyl-CoA + flavonol 3-O-beta-D-glucoside = CoA + flavonol 3-O-(6-O-
CA   malonyl-beta-D-glucoside).
//
ID   2.3.1.117
DE   2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase.
AN   Succinyl-CoA:tetrahydrodipicolinate N-succinyltransferase.
AN   Tetrahydrodipicolinate N-succinyltransferase.
AN   Tetrahydrodipicolinate succinylase.
AN   Tetrahydrodipicolinate succinyltransferase.
CA   Succinyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H(2)O =
CA   CoA + N-succinyl-L-2-amino-6-oxoheptanedioate.
CC   -!- Involved in the biosynthesis of lysine in bacteria, cyanobacteria and
CC       higher plants.
CC   -!- Earlier erroneously called 2,3,4,5-tetrahydropyridine-2-carboxylate
CC       N-succinyltransferase.
PR   PROSITE; PDOC00094;
DR   A1TQ21, DAPD_ACIAC ;  Q6F9A5, DAPD_ACIAD ;  B7GYD0, DAPD_ACIB3 ;
DR   B7I595, DAPD_ACIB5 ;  Q5DL43, DAPD_ACIBA ;  B2HWR7, DAPD_ACIBC ;
DR   B0VTA6, DAPD_ACIBS ;  A3M7R2, DAPD_ACIBT ;  B0VCW7, DAPD_ACIBY ;
DR   B9MJK9, DAPD_ACIET ;  A1W7L8, DAPD_ACISJ ;  A3N3F7, DAPD_ACTP2 ;
DR   P41396, DAPD_ACTPL ;  A6VP50, DAPD_ACTSZ ;  A0KHG0, DAPD_AERHH ;
DR   A4SQI5, DAPD_AERS4 ;  B9J8D1, DAPD_AGRRK ;  Q8UIC6, DAPD_AGRT5 ;
DR   B9JZL8, DAPD_AGRVS ;  Q0A7H6, DAPD_ALHEH ;  B4RVP7, DAPD_ALTMD ;
DR   Q5NYT9, DAPD_AROAE ;  A1K717, DAPD_AZOSB ;  A1UUB8, DAPD_BARBK ;
DR   Q6G549, DAPD_BARHE ;  Q6G1F4, DAPD_BARQU ;  A9ILJ3, DAPD_BART1 ;
DR   B2IDV9, DAPD_BEII9 ;  Q8G3M4, DAPD_BIFLO ;  Q7VRE8, DAPD_BLOFL ;
DR   Q493D4, DAPD_BLOPB ;  Q2L2J5, DAPD_BORA1 ;  P0A4U9, DAPD_BORBR ;
DR   Q7W8Y2, DAPD_BORPA ;  A9IR78, DAPD_BORPD ;  P0A4U8, DAPD_BORPE ;
DR   Q89BP4, DAPD_BRAJA ;  A5ESQ2, DAPD_BRASB ;  A4YLC4, DAPD_BRASO ;
DR   B2SC15, DAPD_BRUA1 ;  Q2YJQ7, DAPD_BRUA2 ;  Q576T5, DAPD_BRUAB ;
DR   A9MCV4, DAPD_BRUC2 ;  C0RMG8, DAPD_BRUMB ;  Q8YDA8, DAPD_BRUME ;
DR   A5VVT4, DAPD_BRUO2 ;  A9WW39, DAPD_BRUSI ;  Q8FV25, DAPD_BRUSU ;
DR   P57323, DAPD_BUCAI ;  O85290, DAPD_BUCAP ;  Q89AP4, DAPD_BUCBP ;
DR   B1YSH7, DAPD_BURA4 ;  Q1BHJ3, DAPD_BURCA ;  B1JUG0, DAPD_BURCC ;
DR   A0K8F4, DAPD_BURCH ;  B4ECP1, DAPD_BURCJ ;  Q0BE05, DAPD_BURCM ;
DR   A9AHT0, DAPD_BURM1 ;  A3MKV6, DAPD_BURM7 ;  A2SB60, DAPD_BURM9 ;
DR   Q62JB3, DAPD_BURMA ;  A1V582, DAPD_BURMS ;  A3NWP3, DAPD_BURP0 ;
DR   A3NAW0, DAPD_BURP6 ;  B2JID7, DAPD_BURP8 ;  B2T5K6, DAPD_BURPP ;
DR   Q63T02, DAPD_BURPS ;  Q39F33, DAPD_BURS3 ;  A4JF86, DAPD_BURVG ;
DR   Q13XA4, DAPD_BURXL ;  Q0P823, DAPD_CAMJE ;  Q9ABE7, DAPD_CAUCR ;
DR   Q7P0W5, DAPD_CHRVO ;  A8ALC4, DAPD_CITK8 ;  Q485H5, DAPD_COLP3 ;
DR   Q8NRE3, DAPD_CORGL ;  B6J928, DAPD_COXB1 ;  B6J119, DAPD_COXB2 ;
DR   A9KC83, DAPD_COXBN ;  A9NCF0, DAPD_COXBR ;  Q83DN1, DAPD_COXBU ;
DR   Q0KA05, DAPD_CUPNH ;  Q470C6, DAPD_CUPPJ ;  B3R2C8, DAPD_CUPTR ;
DR   Q47FA8, DAPD_DECAR ;  A9BZY8, DAPD_DELAS ;  A8LJS9, DAPD_DINSH ;
DR   A7ZHQ6, DAPD_ECO24 ;  B7UIL1, DAPD_ECO27 ;  B7MBE7, DAPD_ECO45 ;
DR   Q8X8Y7, DAPD_ECO57 ;  B5Z0E4, DAPD_ECO5E ;  B7NIC7, DAPD_ECO7I ;
DR   B7M1A5, DAPD_ECO8A ;  C4ZRQ8, DAPD_ECOBW ;  B1XD35, DAPD_ECODH ;
DR   A7ZWB2, DAPD_ECOHS ;  A1A7L0, DAPD_ECOK1 ;  Q0TLG7, DAPD_ECOL5 ;
DR   Q8FL11, DAPD_ECOL6 ;  B1IQH5, DAPD_ECOLC ;  P0A9D8, DAPD_ECOLI ;
DR   B7N833, DAPD_ECOLU ;  B6HZE0, DAPD_ECOSE ;  B1LGW7, DAPD_ECOSM ;
DR   Q1RG24, DAPD_ECOUT ;  C5BHB3, DAPD_EDWI9 ;  Q5FF20, DAPD_EHRRG ;
DR   A4W6R1, DAPD_ENT38 ;  A7MGS1, DAPD_ENTS8 ;  Q6D8E6, DAPD_ERWCT ;
DR   B2VE16, DAPD_ERWT9 ;  B7LWA5, DAPD_ESCF3 ;  D2S9Y8, DAPD_GEOOG ;
DR   Q5FPX6, DAPD_GLUOX ;  Q0BUB8, DAPD_GRABC ;  Q7VNC4, DAPD_HAEDU ;
DR   Q4QL69, DAPD_HAEI8 ;  A5UCM7, DAPD_HAEIE ;  P45284, DAPD_HAEIN ;
DR   Q0I2K0, DAPD_HAES1 ;  B0UTX7, DAPD_HAES2 ;  O25343, DAPD_HELPY ;
DR   A4G4R0, DAPD_HERAR ;  Q5QXS9, DAPD_IDILO ;  A6SZR2, DAPD_JANMA ;
DR   Q28VJ6, DAPD_JANSC ;  P41397, DAPD_KLEOX ;  B5Y1K5, DAPD_KLEP3 ;
DR   A6T4W8, DAPD_KLEP7 ;  C1DD37, DAPD_LARHH ;  Q5X6L6, DAPD_LEGPA ;
DR   A5IG27, DAPD_LEGPC ;  Q5ZX45, DAPD_LEGPH ;  Q5WY20, DAPD_LEGPL ;
DR   B1Y6E5, DAPD_LEPCP ;  Q2W0E8, DAPD_MAGSA ;  Q65TC6, DAPD_MANSM ;
DR   Q0ASJ0, DAPD_MARMM ;  Q11LD4, DAPD_MESSB ;  Q608K0, DAPD_METCA ;
DR   A9W317, DAPD_METEP ;  Q1H054, DAPD_METFK ;  B8IHY5, DAPD_METNO ;
DR   B1ZGG8, DAPD_METPB ;  B0UJH5, DAPD_METS4 ;  C5CBB6, DAPD_MICLC ;
DR   Q7U0E7, DAPD_MYCBO ;  A0R2G5, DAPD_MYCS2 ;  O05302, DAPD_MYCTU ;
DR   Q5F695, DAPD_NEIG1 ;  B4RNN0, DAPD_NEIG2 ;  A9M2Y6, DAPD_NEIM0 ;
DR   Q9JSS7, DAPD_NEIMA ;  Q9K152, DAPD_NEIMB ;  A1KVU9, DAPD_NEIMF ;
DR   Q0AJF8, DAPD_NITEC ;  Q82S90, DAPD_NITEU ;  Q1QH73, DAPD_NITHX ;
DR   Q2Y7X5, DAPD_NITMU ;  Q3J9B1, DAPD_NITOC ;  A6Q5J0, DAPD_NITSB ;
DR   Q3SN24, DAPD_NITWN ;  Q2G798, DAPD_NOVAD ;  A6WYL7, DAPD_OCHA4 ;
DR   B6JJP3, DAPD_OLICO ;  A1B507, DAPD_PARDP ;  A7HPQ7, DAPD_PARL1 ;
DR   Q9CMZ2, DAPD_PASMU ;  Q4FNF4, DAPD_PELUB ;  Q7N8Q0, DAPD_PHOLL ;
DR   A4SYV8, DAPD_POLSQ ;  Q6AA30, DAPD_PROAC ;  B4F2D6, DAPD_PROMH ;
DR   A6V1C2, DAPD_PSEA7 ;  Q3IIZ6, DAPD_PSEHT ;  Q88MP1, DAPD_PSEPK ;
DR   Q4FTR7, DAPD_PSYA2 ;  Q1QCU5, DAPD_PSYCK ;  A5WDV6, DAPD_PSYWF ;
DR   Q1LNH0, DAPD_RALME ;  B2UAZ4, DAPD_RALPJ ;  Q8XZK2, DAPD_RALSO ;
DR   B3PZG1, DAPD_RHIE6 ;  Q2KD46, DAPD_RHIEC ;  Q1MM74, DAPD_RHIL3 ;
DR   Q98D61, DAPD_RHILO ;  B5ZN24, DAPD_RHILW ;  Q92SG5, DAPD_RHIME ;
DR   C3MF35, DAPD_RHISN ;  Q21WT2, DAPD_RHOFD ;  Q07TX5, DAPD_RHOP5 ;
DR   Q6NC47, DAPD_RHOPA ;  Q21B54, DAPD_RHOPB ;  Q13F24, DAPD_RHOPS ;
DR   B3QCH6, DAPD_RHOPT ;  Q2RNM2, DAPD_RHORT ;  A3PNH8, DAPD_RHOS1 ;
DR   Q3IYR9, DAPD_RHOS4 ;  A4WNJ4, DAPD_RHOS5 ;  A8GMH0, DAPD_RICAH ;
DR   Q1RHE0, DAPD_RICBR ;  Q92J26, DAPD_RICCN ;  Q4UKK3, DAPD_RICFE ;
DR   Q9ZDX0, DAPD_RICPR ;  A8GR33, DAPD_RICRS ;  Q68XH5, DAPD_RICTY ;
DR   Q16DM5, DAPD_ROSDO ;  D2NS11, DAPD_ROTMD ;  B5F8S7, DAPD_SALA4 ;
DR   A9MPJ6, DAPD_SALAR ;  Q57T42, DAPD_SALCH ;  B5FJ13, DAPD_SALDC ;
DR   B5R3H8, DAPD_SALEP ;  B5RHF1, DAPD_SALG2 ;  B4TK41, DAPD_SALHS ;
DR   B4SUZ5, DAPD_SALNS ;  Q5PD57, DAPD_SALPA ;  A9N0R2, DAPD_SALPB ;
DR   C0Q5S6, DAPD_SALPC ;  B5BL93, DAPD_SALPK ;  B4TXR8, DAPD_SALSV ;
DR   Q8Z9A8, DAPD_SALTI ;  A4XB85, DAPD_SALTO ;  Q8ZRP4, DAPD_SALTY ;
DR   A8GIE9, DAPD_SERP5 ;  A1S4N7, DAPD_SHEAM ;  A3D2K2, DAPD_SHEB5 ;
DR   A6WLA3, DAPD_SHEB8 ;  A9KUK2, DAPD_SHEB9 ;  Q12NZ0, DAPD_SHEDO ;
DR   Q085E5, DAPD_SHEFN ;  B0TP86, DAPD_SHEHH ;  A3QGA6, DAPD_SHELP ;
DR   Q8EGH9, DAPD_SHEON ;  A8H6L9, DAPD_SHEPA ;  A4Y540, DAPD_SHEPC ;
DR   A0KZ26, DAPD_SHESA ;  A8FY45, DAPD_SHESH ;  Q0HGV2, DAPD_SHESM ;
DR   Q0HT59, DAPD_SHESR ;  A1RLN0, DAPD_SHESW ;  B2U308, DAPD_SHIB3 ;
DR   Q325X4, DAPD_SHIBS ;  Q32JU3, DAPD_SHIDS ;  Q0T843, DAPD_SHIF8 ;
DR   P0A9D9, DAPD_SHIFL ;  Q3Z5J2, DAPD_SHISS ;  Q5LN75, DAPD_SILPO ;
DR   A6U5J9, DAPD_SINMW ;  Q2NRK4, DAPD_SODGM ;  Q9X9V6, DAPD_STRCO ;
DR   Q30RL0, DAPD_SULDN ;  A6QAM9, DAPD_SULNB ;  Q3SJI4, DAPD_THIDA ;
DR   B8GPS1, DAPD_THISH ;  C4L868, DAPD_TOLAT ;  P56220, DAPD_UNKP  ;
DR   C5CLT4, DAPD_VARPS ;  Q9KPN7, DAPD_VIBCH ;  Q8D2G0, DAPD_WIGBR ;
DR   Q73H59, DAPD_WOLPM ;  Q5GSI7, DAPD_WOLTR ;  Q9PH32, DAPD_XYLFA ;
DR   Q87F51, DAPD_XYLFT ;  A1JP86, DAPD_YERE8 ;  A7FFG6, DAPD_YERP3 ;
DR   Q1CAN9, DAPD_YERPA ;  B2JZ37, DAPD_YERPB ;  Q8ZH69, DAPD_YERPE ;
DR   A9R398, DAPD_YERPG ;  Q1CFE3, DAPD_YERPN ;  A4TL95, DAPD_YERPP ;
DR   Q667I6, DAPD_YERPS ;  B1JQF7, DAPD_YERPY ;  Q5NQF0, DAPD_ZYMMO ;
//
ID   2.3.1.118
DE   N-hydroxyarylamine O-acetyltransferase.
AN   Arylamine N-acetyltransferase.
AN   Arylhydroxamate N,O-acetyltransferase.
CA   Acetyl-CoA + an N-hydroxyarylamine = CoA + an N-acetoxyarylamine.
CC   -!- The enzyme from liver, but not that from bacteria, can also catalyze
CC       N-acetylation of arylamines and N,O-acetylation of arylhydroxamates.
DR   P77567, NHOA_ECOLI ;  Q00267, NHOA_SALTY ;
//
ID   2.3.1.119
DE   Icosanoyl-CoA synthase.
AN   Acyl-CoA elongase.
CA   Stearoyl-CoA + malonyl-CoA + 2 NAD(P)H = icosanoyl-CoA + CO(2) + CoA +
CA   2 NAD(P)(+) + H(2)O.
CC   -!- Icosanoyl-CoA can act in place of stearoyl-CoA.
CC   -!- The membrane enzyme brings about the elongation of these long-chain
CC       fatty-acyl-CoAs.
DR   O48780, KCS11_ARATH;  Q38860, KCS18_ARATH;  Q9MAM3, KCS1_ARATH ;
DR   O65677, KCS2_ARATH ;
//
ID   2.3.1.120
DE   Deleted entry.
//
ID   2.3.1.121
DE   1-alkenylglycerophosphoethanolamine O-acyltransferase.
CA   Acyl-CoA + 1-alkenylglycerophosphoethanolamine = CoA + 1-alkenyl-2-
CA   acylglycerophosphoethanolamine.
CC   -!- Long-chain unsaturated acyl-CoAs are the best substrates.
CC   -!- Not identical with EC 2.3.1.104.
//
ID   2.3.1.122
DE   Trehalose O-mycolyltransferase.
CA   2 alpha,alpha'-trehalose 6-mycolate = alpha,alpha'-trehalose +
CA   alpha,alpha'-trehalose 6,6'-bismycolate.
CC   -!- Catalyzes the exchange of mycolic acid between trehalose, trehalose
CC       mycolate and trehalose bismycolate.
CC   -!- Trehalose 6-palmitate can also act as donor.
//
ID   2.3.1.123
DE   Dolichol O-acyltransferase.
CA   Palmitoyl-CoA + dolichol = CoA + dolichyl palmitate.
CC   -!- Other acyl-CoAs can act, more slowly.
CC   -!- Alpha-saturated dolichols are acylated more rapidly than the alpha-
CC       unsaturated analogs.
//
ID   2.3.1.124
DE   Deleted entry.
//
ID   2.3.1.125
DE   1-alkyl-2-acetylglycerol O-acyltransferase.
AN   1-hexadecyl-2-acetylglycerol acyltransferase.
CA   Acyl-CoA + 1-O-alkyl-2-acetyl-sn-glycerol = CoA + 1-O-alkyl-2-acetyl-3-
CA   acyl-sn-glycerol.
CC   -!- A number of acyl-CoAs can act as acyl donor; maximum activity is
CC       obtained with linoleoyl-CoA.
CC   -!- Not identical with EC 2.3.1.20.
//
ID   2.3.1.126
DE   Isocitrate O-dihydroxycinnamoyltransferase.
CA   Caffeoyl-CoA + isocitrate = CoA + 2-caffeoylisocitrate.
CC   -!- Feruloyl-CoA and 4-coumaroyl-CoA can also act as donors.
//
ID   2.3.1.127
DE   Ornithine N-benzoyltransferase.
CA   2 benzoyl-CoA + L-ornithine = 2 CoA + N(2),N(5)-dibenzoyl-L-ornithine.
//
ID   2.3.1.128
DE   Ribosomal-protein-alanine N-acetyltransferase.
CA   Acetyl-CoA + ribosomal-protein L-alanine = CoA + ribosomal-protein
CA   N-acetyl-L-alanine.
CC   -!- A groups of enzymes in Escherichia coli that acetylate the N-terminal
CC       alanine residues of specific ribosomal proteins (cf. EC 2.3.1.88).
DR   O05517, RIMI_BACSU ;  P0A946, RIMI_ECO57 ;  P0A945, RIMI_ECOL6 ;
DR   P0A944, RIMI_ECOLI ;  Q7VP85, RIMI_HAEDU ;  P44305, RIMI_HAEIN ;
DR   P0A947, RIMI_SHIFL ;  P0A949, RIMJ_ECO57 ;  P0A948, RIMJ_ECOLI ;
DR   Q9I2H6, RIMJ_PSEAE ;  P0A950, RIMJ_SHIFL ;  O31633, YJCK_BACSU ;
//
ID   2.3.1.129
DE   Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase.
AN   Acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase.
AN   UDP-N-acetylglucosamine acyltransferase.
CA   (R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-
CA   acetylglucosamine = [acyl-carrier-protein] + UDP-3-
CA   O-(3-hydroxytetradecanoyl)-N-acetylglucosamine.
CC   -!- Involved with EC 2.4.1.182 and EC 2.7.1.130 in the biosynthesis of
CC       the phosphorylated glycolipid, lipid A, in the outer membrane of
CC       Escherichia coli.
PR   PROSITE; PDOC00094;
DR   A1TN81, LPXA_ACIAC ;  A3MZC5, LPXA_ACTP2 ;  B3H0S1, LPXA_ACTP7 ;
DR   A6VQJ6, LPXA_ACTSZ ;  A0KHH5, LPXA_AERHH ;  A4SQH0, LPXA_AERS4 ;
DR   B9JEY0, LPXA_AGRRK ;  Q8UFL3, LPXA_AGRT5 ;  B9JX23, LPXA_AGRVS ;
DR   B2ULY0, LPXA_AKKM8 ;  Q0A7J1, LPXA_ALHEH ;  B6EJW8, LPXA_ALISL ;
DR   Q46481, LPXA_ALLVD ;  B8JFW9, LPXA_ANAD2 ;  Q2IPX7, LPXA_ANADE ;
DR   A7H9D6, LPXA_ANADF ;  B4UGV2, LPXA_ANASK ;  O66862, LPXA_AQUAE ;
DR   A8EWV5, LPXA_ARCB4 ;  A8I491, LPXA_AZOC5 ;  C1DST4, LPXA_AZOVD ;
DR   A1USE7, LPXA_BARBK ;  Q8VQ21, LPXA_BARHE ;  Q6G1J6, LPXA_BARQU ;
DR   A9ISM8, LPXA_BART1 ;  Q7VRD4, LPXA_BLOFL ;  Q493C0, LPXA_BLOPB ;
DR   B2S601, LPXA_BRUA1 ;  Q2YRQ5, LPXA_BRUA2 ;  P0C110, LPXA_BRUAB ;
DR   A9M5G4, LPXA_BRUC2 ;  C0RJC0, LPXA_BRUMB ;  P65320, LPXA_BRUME ;
DR   A5VQS3, LPXA_BRUO2 ;  B0CGU9, LPXA_BRUSI ;  P65321, LPXA_BRUSU ;
DR   B1YS62, LPXA_BURA4 ;  Q1BHH0, LPXA_BURCA ;  B1JUD8, LPXA_BURCC ;
DR   A0K8D1, LPXA_BURCH ;  B4ECL9, LPXA_BURCJ ;  Q0BE27, LPXA_BURCM ;
DR   A9AIM6, LPXA_BURM1 ;  A3MKT0, LPXA_BURM7 ;  A2SB85, LPXA_BURM9 ;
DR   Q62JD6, LPXA_BURMA ;  A1V556, LPXA_BURMS ;  A3NWL8, LPXA_BURP0 ;
DR   Q3JR41, LPXA_BURP1 ;  A3NAT5, LPXA_BURP6 ;  B2JIB4, LPXA_BURP8 ;
DR   B2T5I2, LPXA_BURPP ;  Q63T24, LPXA_BURPS ;  Q39F55, LPXA_BURS3 ;
DR   Q2SWY6, LPXA_BURTA ;  A4JF63, LPXA_BURVG ;  Q13XC8, LPXA_BURXL ;
DR   A8Z6P9, LPXA_CAMC1 ;  A7GWE8, LPXA_CAMC5 ;  A8FK63, LPXA_CAMJ8 ;
DR   A7H597, LPXA_CAMJD ;  Q9PIM1, LPXA_CAMJE ;  A1VXZ8, LPXA_CAMJJ ;
DR   Q5HWJ2, LPXA_CAMJR ;  B9KDS6, LPXA_CAMLR ;  B8GWR1, LPXA_CAUCN ;
DR   Q9A715, LPXA_CAUCR ;  Q5L723, LPXA_CHLAB ;  Q820F0, LPXA_CHLCV ;
DR   Q252V0, LPXA_CHLFF ;  Q9PJL1, LPXA_CHLMU ;  B3QR04, LPXA_CHLP8 ;
DR   A1BIY4, LPXA_CHLPD ;  Q9Z7Q4, LPXA_CHLPN ;  B0B8A5, LPXA_CHLT2 ;
DR   Q3KLG6, LPXA_CHLTA ;  B0B9Y4, LPXA_CHLTB ;  Q8KAZ0, LPXA_CHLTE ;
DR   O84536, LPXA_CHLTR ;  Q0KA28, LPXA_CUPNH ;  Q470E9, LPXA_CUPPJ ;
DR   B3R2A5, LPXA_CUPTR ;  Q9TLX4, LPXA_CYACA ;  B7KFS2, LPXA_CYAP7 ;
DR   B7JW27, LPXA_CYAP8 ;  A7ZHS1, LPXA_ECO24 ;  B7UJ82, LPXA_ECO27 ;
DR   B7MBG2, LPXA_ECO45 ;  B7LGP3, LPXA_ECO55 ;  Q8X8X8, LPXA_ECO57 ;
DR   B5Z0G0, LPXA_ECO5E ;  B7NIE3, LPXA_ECO7I ;  B7MP41, LPXA_ECO81 ;
DR   B7M1Y4, LPXA_ECO8A ;  C4ZRS3, LPXA_ECOBW ;  B1XD50, LPXA_ECODH ;
DR   A7ZWC7, LPXA_ECOHS ;  A1A7M5, LPXA_ECOK1 ;  Q0TLF2, LPXA_ECOL5 ;
DR   P0A723, LPXA_ECOL6 ;  B1IQG0, LPXA_ECOLC ;  P0A722, LPXA_ECOLI ;
DR   B7N848, LPXA_ECOLU ;  B6HZF5, LPXA_ECOSE ;  B1LGY3, LPXA_ECOSM ;
DR   Q1RG08, LPXA_ECOUT ;  A4W6S6, LPXA_ENT38 ;  A7MI18, LPXA_ENTS8 ;
DR   Q6D8D1, LPXA_ERWCT ;  B2VHX8, LPXA_ERWT9 ;  B7LW80, LPXA_ESCF3 ;
DR   Q8RFU2, LPXA_FUSNN ;  B3E4H5, LPXA_GEOLS ;  Q7VM26, LPXA_HAEDU ;
DR   Q4QLM5, LPXA_HAEI8 ;  A5UD43, LPXA_HAEIE ;  P43887, LPXA_HAEIN ;
DR   B8F6B1, LPXA_HAEPS ;  Q0I4M4, LPXA_HAES1 ;  B0UW61, LPXA_HAES2 ;
DR   A1WX11, LPXA_HALHL ;  C4K437, LPXA_HAMD5 ;  Q17ZK1, LPXA_HELAH ;
DR   B6JNP1, LPXA_HELP2 ;  B5Z919, LPXA_HELPG ;  Q1CRN4, LPXA_HELPH ;
DR   Q9ZJL7, LPXA_HELPJ ;  B2UVD9, LPXA_HELPS ;  O25927, LPXA_HELPY ;
DR   A4G4T3, LPXA_HERAR ;  A6SZN9, LPXA_JANMA ;  B5Y1J0, LPXA_KLEP3 ;
DR   A6T4Y3, LPXA_KLEP7 ;  B1XXI3, LPXA_LEPCP ;  Q65VE2, LPXA_MANSM ;
DR   B1LTP4, LPXA_METRJ ;  Q1D387, LPXA_MYXXD ;  B9L772, LPXA_NAUPA ;
DR   Q5F5W3, LPXA_NEIG1 ;  B4RR10, LPXA_NEIG2 ;  A9M3T0, LPXA_NEIM0 ;
DR   Q9JX26, LPXA_NEIMA ;  P95379, LPXA_NEIMB ;  A1KRK9, LPXA_NEIMF ;
DR   A6X0K1, LPXA_OCHA4 ;  A1B8X9, LPXA_PARDP ;  Q9CJK8, LPXA_PASMU ;
DR   C6DAJ5, LPXA_PECCP ;  Q7N8N5, LPXA_PHOLL ;  B1XTV5, LPXA_POLNS ;
DR   A4SYT9, LPXA_POLSQ ;  B4F258, LPXA_PROMH ;  P72215, LPXA_PROMI ;
DR   Q48F71, LPXA_PSE14 ;  A6V1E4, LPXA_PSEA7 ;  B7V7U4, LPXA_PSEA8 ;
DR   Q02RB6, LPXA_PSEAB ;  Q9X6P4, LPXA_PSEAE ;  Q1I638, LPXA_PSEE4 ;
DR   Q4KHG4, LPXA_PSEF5 ;  C3K607, LPXA_PSEFS ;  A4XWS9, LPXA_PSEMY ;
DR   A5W838, LPXA_PSEP1 ;  Q3KHA0, LPXA_PSEPF ;  B0KSB1, LPXA_PSEPG ;
DR   Q88MG8, LPXA_PSEPK ;  B1JBP8, LPXA_PSEPW ;  Q886N1, LPXA_PSESM ;
DR   Q4ZWR6, LPXA_PSEU2 ;  A4VJT3, LPXA_PSEU5 ;  Q4FRI4, LPXA_PSYA2 ;
DR   Q1QA21, LPXA_PSYCK ;  A1SYV1, LPXA_PSYIN ;  A5WGE2, LPXA_PSYWF ;
DR   Q1LNE6, LPXA_RALME ;  B2UBB3, LPXA_RALPJ ;  Q8XZH9, LPXA_RALSO ;
DR   B3PYQ2, LPXA_RHIE6 ;  Q2K8X7, LPXA_RHIEC ;  Q1MH44, LPXA_RHIL3 ;
DR   Q98MC6, LPXA_RHILO ;  B5ZN93, LPXA_RHILW ;  Q92Q45, LPXA_RHIME ;
DR   C3MBR2, LPXA_RHISN ;  Q21WX8, LPXA_RHOFD ;  C3PM36, LPXA_RICAE ;
DR   A8GUZ4, LPXA_RICB8 ;  Q1RH96, LPXA_RICBR ;  A8EX76, LPXA_RICCK ;
DR   Q92JQ9, LPXA_RICCN ;  Q4UNJ9, LPXA_RICFE ;  Q9ZED5, LPXA_RICPR ;
DR   C4K0C1, LPXA_RICPU ;  P32199, LPXA_RICRI ;  B0BVR3, LPXA_RICRO ;
DR   A8GQC8, LPXA_RICRS ;  Q68XZ6, LPXA_RICTY ;  Q21HI4, LPXA_SACD2 ;
DR   B5F8U2, LPXA_SALA4 ;  A9MPI0, LPXA_SALAR ;  Q57T27, LPXA_SALCH ;
DR   B5FJ28, LPXA_SALDC ;  B5R420, LPXA_SALEP ;  B5RHG6, LPXA_SALG2 ;
DR   B4TK56, LPXA_SALHS ;  B4SV10, LPXA_SALNS ;  Q5PD73, LPXA_SALPA ;
DR   A9N0T1, LPXA_SALPB ;  C0Q6K4, LPXA_SALPC ;  B5BAN8, LPXA_SALPK ;
DR   B4TYE1, LPXA_SALSV ;  Q8Z9A2, LPXA_SALTI ;  P32200, LPXA_SALTY ;
DR   A8GID4, LPXA_SERP5 ;  B2U324, LPXA_SHIB3 ;  Q325V9, LPXA_SHIBS ;
DR   Q32JS8, LPXA_SHIDS ;  Q0T828, LPXA_SHIF8 ;  P0A724, LPXA_SHIFL ;
DR   Q3Z5H7, LPXA_SHISS ;  A6U8L2, LPXA_SINMW ;  Q2NRL9, LPXA_SODGM ;
DR   B4SQ11, LPXA_STRM5 ;  B2FHN6, LPXA_STRMK ;  Q30QJ1, LPXA_SULDN ;
DR   A6Q9A7, LPXA_SULNB ;  B2V7U3, LPXA_SULSY ;  Q2LVL6, LPXA_SYNAS ;
DR   A0LPR7, LPXA_SYNFM ;  Q55746, LPXA_SYNY3 ;  B5YHC0, LPXA_THEYD ;
DR   Q3SKM9, LPXA_THIDA ;  C4L852, LPXA_TOLAT ;  C5CKT2, LPXA_VARPS ;
DR   A1WHV4, LPXA_VEREI ;  A5F628, LPXA_VIBC3 ;  Q9KPW4, LPXA_VIBCH ;
DR   C3LQ20, LPXA_VIBCM ;  Q5E3F1, LPXA_VIBF1 ;  B5F9W4, LPXA_VIBFM ;
DR   A7MY03, LPXA_VIBHB ;  Q87ME9, LPXA_VIBPA ;  B7VIQ6, LPXA_VIBSL ;
DR   Q8DBE9, LPXA_VIBVU ;  Q7MIH1, LPXA_VIBVY ;  Q8D2H3, LPXA_WIGBR ;
DR   Q8PML7, LPXA_XANAC ;  Q3BVL6, LPXA_XANC5 ;  Q4USP8, LPXA_XANC8 ;
DR   B0RW78, LPXA_XANCB ;  Q8PAW5, LPXA_XANCP ;  Q2P4B7, LPXA_XANOM ;
DR   B2SR11, LPXA_XANOP ;  Q5H1F2, LPXA_XANOR ;  Q9PEI5, LPXA_XYLFA ;
DR   Q87EI4, LPXA_XYLFT ;  A1JP69, LPXA_YERE8 ;  P32201, LPXA_YEREN ;
DR   A7FFI1, LPXA_YERP3 ;  Q1CAM2, LPXA_YERPA ;  B2JZ22, LPXA_YERPB ;
DR   Q8ZH56, LPXA_YERPE ;  A9R384, LPXA_YERPG ;  Q1CFF9, LPXA_YERPN ;
DR   A4TL79, LPXA_YERPP ;  Q667K1, LPXA_YERPS ;  B1JQH2, LPXA_YERPY ;
//
ID   2.3.1.130
DE   Galactarate O-hydroxycinnamoyltransferase.
CA   Feruloyl-CoA + galactarate = CoA + O-feruloylgalactarate.
CC   -!- Sinapoyl-CoA and 4-coumaroyl-CoA can also act as donors.
//
ID   2.3.1.131
DE   Glucarate O-hydroxycinnamoyltransferase.
CA   Sinapoyl-CoA + glucarate = CoA + O-sinapoylglucarate.
CC   -!- 4-coumaroyl-CoA, feruloyl-CoA and caffeoyl-CoA can also act as
CC       donors, more slowly.
//
ID   2.3.1.132
DE   Glucarolactone O-hydroxycinnamoyltransferase.
CA   Sinapoyl-CoA + glucarolactone = CoA + O-sinapoylglucarolactone.
CC   -!- 4-coumaroyl-CoA, feruloyl-CoA and caffeoyl-CoA can also act as
CC       donors, more slowly.
//
ID   2.3.1.133
DE   Shikimate O-hydroxycinnamoyltransferase.
CA   4-coumaroyl-CoA + shikimate = CoA + 4-coumaroylshikimate.
CC   -!- Caffeoyl-CoA, feruloyl-CoA and sinapoyl-CoA can also act as donors,
CC       more slowly.
//
ID   2.3.1.134
DE   Galactolipid O-acyltransferase.
AN   Galactolipid:galactolipid acyltransferase.
CA   2 mono-beta-D-galactosyldiacylglycerol = acylmono-beta-D-
CA   galactosyldiacylglycerol + mono-beta-D-galactosylacylglycerol.
CC   -!- Di-D-galactosyldiacylglycerol can also act as acceptor.
//
ID   2.3.1.135
DE   Phosphatidylcholine--retinol O-acyltransferase.
AN   Lecithin--retinol acyltransferase.
CA   Phosphatidylcholine + retinol--[cellular-retinol-binding-protein] =
CA   2-acylglycerophosphocholine + retinyl-ester--[cellular-retinol-binding-
CA   protein].
CC   -!- Specific for transfer of the sn-1-acyl residue of
CC       phosphatidylcholine.
DR   Q9BGL2, LRAT_BOVIN ;  O95237, LRAT_HUMAN ;  Q9JI60, LRAT_MOUSE ;
DR   Q9JI61, LRAT_RAT   ;
//
ID   2.3.1.136
DE   Polysialic-acid O-acetyltransferase.
CA   Acetyl-CoA + an alpha-2,8-linked polymer of sialic acid = CoA +
CA   polysialic acid acetylated at O-7 or O-9.
CC   -!- Acts only on substrates containing more than 14 sialosyl residues.
CC   -!- Catalyzes the modification of capsular polysaccharides in some
CC       strains of Escherichia coli.
//
ID   2.3.1.137
DE   Carnitine O-octanoyltransferase.
CA   Octanoyl-CoA + L-carnitine = CoA + L-octanoylcarnitine.
CC   -!- Acts on a range of acyl-CoAs, with optimal activity with C(6) or C(8)
CC       acyl groups.
CC   -!- Cf. EC 2.3.1.7 and EC 2.3.1.21.
DR   O19094, OCTC_BOVIN ;  Q9UKG9, OCTC_HUMAN ;  Q9DC50, OCTC_MOUSE ;
DR   P11466, OCTC_RAT   ;
//
ID   2.3.1.138
DE   Putrescine N-hydroxycinnamoyltransferase.
CA   Caffeoyl-CoA + putrescine = CoA + N-caffeoylputrescine.
CC   -!- Feruloyl-CoA, cinnamoyl-CoA and sinapoyl-CoA can also act as donors,
CC       more slowly.
//
ID   2.3.1.139
DE   Ecdysone O-acyltransferase.
CA   Palmitoyl-CoA + ecdysone = CoA + ecdysone palmitate.
//
ID   2.3.1.140
DE   Rosmarinate synthase.
CA   Caffeoyl-CoA + 3-(3,4-dihydroxyphenyl)lactate = CoA + rosmarinate.
CC   -!- Involved with EC 1.1.1.237 in the biosynthesis of rosmarinic acid.
//
ID   2.3.1.141
DE   Galactosylacylglycerol O-acyltransferase.
CA   Acyl-[acyl-carrier-protein] + sn-3-D-galactosyl-sn-2-acylglycerol =
CA   [acyl-carrier-protein] + D-galactosyldiacylglycerol.
CC   -!- Transfers long-chain acyl groups to the sn-1 position of the glycerol
CC       residues.
//
ID   2.3.1.142
DE   Glycoprotein O-fatty-acyltransferase.
CA   Palmitoyl-CoA + mucus glycoprotein = CoA + O-palmitoylglycoprotein.
//
ID   2.3.1.143
DE   Beta-glucogallin--tetrakisgalloylglucose O-galloyltransferase.
CA   1-O-galloyl-beta-D-glucose + 1,2,3,6-tetrakis-O-galloyl-beta-D-glucose =
CA   D-glucose + 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose.
//
ID   2.3.1.144
DE   Anthranilate N-benzoyltransferase.
CA   Benzoyl-CoA + anthranilate = CoA + N-benzoylanthranilate.
CC   -!- Cinnamoyl-CoA, 4-coumaroyl-CoA and salicyloyl-CoA can act as donors,
CC       more slowly.
CC   -!- Involved in the biosynthesis of phytoalexins.
DR   O24645, HCBT1_DIACA;  O23917, HCBT2_DIACA;  O23918, HCBT3_DIACA;
//
ID   2.3.1.145
DE   Piperidine N-piperoyltransferase.
CA   (E,E)-piperoyl-CoA + piperidine = CoA + N-((E,E)-piperoyl)-piperidine.
CC   -!- Pyrrolidine and 3-pyrroline can also act as acceptors, more slowly.
//
ID   2.3.1.146
DE   Pinosylvin synthase.
AN   Stilbene synthase.
CA   3 malonyl-CoA + cinnamoyl-CoA = 4 CoA + pinosylvin + 4 CO(2).
CC   -!- Not identical with EC 2.3.1.74 or EC 2.3.1.95.
//
ID   2.3.1.147
DE   Glycerophospholipid arachidonoyl-transferase (CoA-independent).
CA   1-organyl-2-arachidonoyl-sn-glycero-3-phosphocholine + 1-organyl-2-lyso-
CA   sn-glycero-3-phosphoethanolamine = 1-organyl-2-arachidonoyl-sn-glycero-3-
CA   phosphoethanolamine + 1-organyl-2-lyso-sn-glycero-3-phosphocholine.
CC   -!- Catalyzes the transfer of arachidonate and other polyenoic fatty
CC       acids from intact choline or ethanolamine-containing
CC       glycerophospholipids to the sn-2 position of a lyso-
CC       glycerophospholipid.
CC   -!- The organyl group on sn-1 of the donor or acceptor molecule can be
CC       alkyl, acyl or alk-1-enyl.
CC   -!- The term 'radyl' has sometimes been used to refer to such
CC       substituting groups.
CC   -!- Differs from EC 2.3.1.148 in not requiring CoA and in its specificity
CC       for poly-unsaturated acyl groups.
//
ID   2.3.1.148
DE   Glycerophospholipid acyltransferase (CoA-dependent).
CA   1-organyl-2-acyl-sn-glycero-3-phosphocholine + 1-organyl-2-lyso-
CA   sn-glycero-3-phosphoethanolamine = 1-organyl-2-acyl-sn-glycero-3-
CA   phosphoethanolamine + 1-organyl-2-lyso-sn-glycero-3-phosphocholine.
CF   CoA.
CC   -!- Catalyzes the transfer of fatty acids from intact choline- or
CC       ethanolamine-containing glycerophospholipids to the sn-2 position of
CC       a lyso-glycerophospholipid.
CC   -!- The organyl group on sn-1 of the donor or acceptor molecule can be
CC       alkyl, acyl or alk-1-enyl.
CC   -!- The term 'radyl' has sometimes been used to refer to such
CC       substituting groups.
CC   -!- Differs from EC 2.3.1.147 in requiring CoA and not favoring the
CC       transfer of polyunsaturated acyl groups.
//
ID   2.3.1.149
DE   Platelet-activating factor acetyltransferase.
AN   PAF acetyltransferase.
CA   1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + 1-organyl-2-lyso-
CA   sn-glycero-3-phospholipid = 1-organyl-2-lyso-sn-glycero-3-phosphocholine
CA   + 1-alkyl-2-acetyl-sn-glycero-3-phospholipid.
CC   -!- Catalyzes the transfer of the acetyl group from 1-alkyl-2-acyl-
CC       sn-glycero-3-phosphocholine (platelet-activating factor) to the sn-2
CC       position of lyso-glycerophospholipids containing ethanolamine,
CC       choline, serine, inositol or phosphate groups at the sn-3 position as
CC       well as to sphingosine and long-chain fatty alcohols.
CC   -!- The organyl group can be alkyl, acyl or alk-1-enyl (sometimes also
CC       collectively referred to as 'radyl').
//
ID   2.3.1.150
DE   Salutaridinol 7-O-acetyltransferase.
CA   Acetyl-CoA + salutaridinol = CoA + 7-O-acetylsalutaridinol.
CC   -!- At higher pH values the product, 7-O-acetylsalutaridinol,
CC       spontaneously closes the 4->5 oxide bridge by allylic elimination to
CC       form the morphine precursor thebaine.
CC   -!- From the opium poppy plant, Papaver somniferum.
DR   Q94FT4, SALAT_PAPSO;
//
ID   2.3.1.151
DE   Benzophenone synthase.
CA   3 malonyl-CoA + 3-hydroxybenzoyl-CoA = 4 CoA + 2,3',4,6-
CA   tetrahydroxybenzophenone + 3 CO(2).
CC   -!- Involved in the biosynthesis of plant xanthomes.
CC   -!- Benzoyl-CoA can replace 3-hydroxybenzoyl-CoA.
//
ID   2.3.1.152
DE   Alcohol O-cinnamoyltransferase.
CA   1-O-trans-cinnamoyl-beta-D-glucopyranose + ROH = alkyl cinnamate +
CA   glucose.
CC   -!- Acceptor alcohols (ROH) include methanol, ethanol and propanol.
CC   -!- No cofactors are required as 1-O-trans-cinnamoyl-beta-D-glucopyranose
CC       itself is an 'energy-rich' (activated) acyl-donor, comparable to CoA-
CC       thioesters.
CC   -!- 1-O-trans-cinnamoyl-beta-D-gentobiose can also act as the acyl donor,
CC       but with much less affinity.
//
ID   2.3.1.153
DE   Anthocyanin 5-aromatic acyltransferase.
CA   Hydroxycinnamoyl-CoA + anthocyanidin-3,5-diglucoside = CoA +
CA   anthocyanidin 3-glucoside-5-hydroxycinnamoylglucoside.
CC   -!- Transfers the hydroxycinnamoyl group only to the C-5 glucoside of
CC       anthocyanin.
CC   -!- Malonyl-CoA cannot act as a donor.
DR   Q9ZWR8, ANTA_GENTR ;
//
ID   2.3.1.154
DE   Propionyl-CoA C(2)-trimethyltridecanoyltransferase.
AN   3-oxopristanoyl-CoA hydrolase.
AN   3-oxopristanoyl-CoA thiolase.
CA   4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA +
CA   CoA.
CC   -!- The peroxisomal protein sterol carrier protein X (SCPx) combines this
CC       thiolase activity with its carrier function, and is involved in
CC       branched chain fatty acid beta-oxidation in peroxisomes.
CC   -!- It also acts on 3-oxopalmitoyl-CoA as a substrate but differs from
CC       EC 2.3.1.16 which has little activity toward the 3-oxoacyl-CoA esters
CC       of 2-methyl-branched chain fatty acids such as 3-oxopristanoyl-CoA.
//
ID   2.3.1.155
DE   Acetyl-CoA C-myristoyltransferase.
AN   3-oxopalmitoyl-CoA hydrolase.
AN   3-oxopalmitoyl-CoA-CoA acetyltransferase.
AN   Myristoyl-CoA C-acetyltransferase.
CA   Myristoyl-CoA + acetyl-CoA = 3-oxopalmitoyl-CoA + CoA.
CC   -!- A peroxisomal enzyme involved in branched chain fatty acid beta-
CC       oxidation in peroxisomes.
CC   -!- It differs from EC 2.3.1.154 in not being active toward
CC       3-oxopristanoyl-CoA.
//
ID   2.3.1.156
DE   Phloroisovalerophenone synthase.
AN   3-methyl-1-(trihydroxyphenyl)butan-1-one synthase.
AN   Valerophenone synthase.
CA   Isovaleryl-CoA + 3 malonyl-CoA = 4 CoA + 3 CO(2) + 3-methyl-1-(2,4,6-
CA   trihydroxyphenyl)butan-1-one.
CC   -!- Closely related to EC 2.3.1.74.
CC   -!- The product, 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one,
CC       is phloroisovalerophenone.
CC   -!- Also acts on isobutyryl-CoA as substrate to give
CC       phlorisobutyrophenone.
CC   -!- The products are intermediates in the biosynthesis of the bitter
CC       (alpha) acids in hops (Humulus lupulus).
PR   PROSITE; PDOC00403;
DR   O80400, VPS_HUMLU  ;  Q9SLX9, VPS_PSINU  ;
//
ID   2.3.1.157
DE   Glucosamine-1-phosphate N-acetyltransferase.
CA   Acetyl-CoA + alpha-D-glucosamine 1-phosphate = CoA + N-acetyl-alpha-D-
CA   glucosamine 1-phosphate.
CC   -!- The enzyme from several bacteria has been shown to be bifunctional
CC       and also to possess the activity of EC 2.7.7.23.
DR   B0C3K5, GLMU_ACAM1 ;  A9NH16, GLMU_ACHLI ;  A1TUE2, GLMU_ACIAC ;
DR   Q6F6U9, GLMU_ACIAD ;  B2I2B5, GLMU_ACIBC ;  Q1IQY5, GLMU_ACIBL ;
DR   B0VPT6, GLMU_ACIBS ;  B0V9X1, GLMU_ACIBY ;  A5G0T8, GLMU_ACICJ ;
DR   B9MD63, GLMU_ACIET ;  B7JB82, GLMU_ACIF2 ;  B5ER40, GLMU_ACIF5 ;
DR   A1W3Q7, GLMU_ACISJ ;  A3MZV4, GLMU_ACTP2 ;  B3H116, GLMU_ACTP7 ;
DR   B0BUE6, GLMU_ACTPJ ;  A6VLS5, GLMU_ACTSZ ;  A0KQX6, GLMU_AERHH ;
DR   B9JF80, GLMU_AGRRK ;  Q8UEH0, GLMU_AGRT5 ;  B9JWC4, GLMU_AGRVS ;
DR   Q0VKX6, GLMU_ALCBS ;  Q0A4N0, GLMU_ALHEH ;  B6EHG2, GLMU_ALISL ;
DR   A6TJM5, GLMU_ALKMQ ;  A8MK45, GLMU_ALKOO ;  B4S0Y2, GLMU_ALTMD ;
DR   B8J9N1, GLMU_ANAD2 ;  Q2IGL4, GLMU_ANADE ;  A7H7I2, GLMU_ANADF ;
DR   B9KHH2, GLMU_ANAMF ;  Q5PBV0, GLMU_ANAMM ;  B4UGJ1, GLMU_ANASK ;
DR   Q3MC88, GLMU_ANAVT ;  O66863, GLMU_AQUAE ;  A8EWU5, GLMU_ARCB4 ;
DR   Q5P5P9, GLMU_AROAE ;  A1R4G1, GLMU_ARTAT ;  B8HFD9, GLMU_ARTCA ;
DR   A8I4D4, GLMU_AZOC5 ;  A1KBP7, GLMU_AZOSB ;  C1DMJ0, GLMU_AZOVD ;
DR   A7Z0H3, GLMU_BACA2 ;  C3P9J5, GLMU_BACAA ;  C3LJ22, GLMU_BACAC ;
DR   A0R8C1, GLMU_BACAH ;  Q81VZ1, GLMU_BACAN ;  B7JK56, GLMU_BACC0 ;
DR   Q73FF9, GLMU_BACC1 ;  B7ISV9, GLMU_BACC2 ;  C1ESX9, GLMU_BACC3 ;
DR   B7HIL7, GLMU_BACC4 ;  B7HPW0, GLMU_BACC7 ;  P42817, GLMU_BACCL ;
DR   A7GJW1, GLMU_BACCN ;  B9IZD2, GLMU_BACCQ ;  Q81J98, GLMU_BACCR ;
DR   Q63HI4, GLMU_BACCZ ;  Q9KGJ6, GLMU_BACHD ;  Q6HPW8, GLMU_BACHK ;
DR   Q65PH1, GLMU_BACLD ;  P28017, GLMU_BACME ;  Q5WAD9, GLMU_BACSK ;
DR   P14192, GLMU_BACSU ;  A9VN62, GLMU_BACWK ;  A1USU8, GLMU_BARBK ;
DR   Q6G321, GLMU_BARHE ;  Q6FZH5, GLMU_BARQU ;  A9IVJ6, GLMU_BART1 ;
DR   Q1LTV6, GLMU_BAUCH ;  Q6MHV9, GLMU_BDEBA ;  B8DU78, GLMU_BIFA0 ;
DR   A1A1R9, GLMU_BIFAA ;  B3DSP5, GLMU_BIFLD ;  Q8G5P1, GLMU_BIFLO ;
DR   B7GSX2, GLMU_BIFLS ;  Q7VQV4, GLMU_BLOFL ;  Q494C1, GLMU_BLOPB ;
DR   Q2KTX5, GLMU_BORA1 ;  Q7WE21, GLMU_BORBR ;  Q7W321, GLMU_BORPA ;
DR   A9HWM1, GLMU_BORPD ;  Q7VT27, GLMU_BORPE ;  Q89LD7, GLMU_BRAJA ;
DR   A4YUF4, GLMU_BRASO ;  C0ZHD4, GLMU_BREBN ;  B2SB72, GLMU_BRUA1 ;
DR   Q2YKK2, GLMU_BRUA2 ;  Q577Y2, GLMU_BRUAB ;  A9MBM3, GLMU_BRUC2 ;
DR   C0RLA4, GLMU_BRUMB ;  Q8YC48, GLMU_BRUME ;  A9WYQ2, GLMU_BRUSI ;
DR   Q8FW78, GLMU_BRUSU ;  B8D8J0, GLMU_BUCA5 ;  P57139, GLMU_BUCAI ;
DR   Q8KA74, GLMU_BUCAP ;  B8D6U4, GLMU_BUCAT ;  Q89B26, GLMU_BUCBP ;
DR   B1YP62, GLMU_BURA4 ;  Q1BSY8, GLMU_BURCA ;  B1JZU8, GLMU_BURCC ;
DR   A0KB52, GLMU_BURCH ;  B4E935, GLMU_BURCJ ;  Q0BB89, GLMU_BURCM ;
DR   A9AKB1, GLMU_BURM1 ;  A3MND6, GLMU_BURM7 ;  Q62EP0, GLMU_BURMA ;
DR   A1V7Z3, GLMU_BURMS ;  A3NQK0, GLMU_BURP0 ;  Q3JWX1, GLMU_BURP1 ;
DR   A3N4V7, GLMU_BURP6 ;  B2JIL7, GLMU_BURP8 ;  B2T6U5, GLMU_BURPP ;
DR   Q63Y75, GLMU_BURPS ;  Q39C92, GLMU_BURS3 ;  Q2T1V2, GLMU_BURTA ;
DR   A4JIF7, GLMU_BURVG ;  Q13T65, GLMU_BURXL ;  A4XIS1, GLMU_CALS8 ;
DR   A7ZCS8, GLMU_CAMC1 ;  A7GY50, GLMU_CAMC5 ;  A0RNZ5, GLMU_CAMFF ;
DR   A7I1Y8, GLMU_CAMHC ;  A8FLN0, GLMU_CAMJ8 ;  A7H432, GLMU_CAMJD ;
DR   Q9PPA2, GLMU_CAMJE ;  A1VZG5, GLMU_CAMJJ ;  Q5HUX5, GLMU_CAMJR ;
DR   B9KCL5, GLMU_CAMLR ;  Q3AFM0, GLMU_CARHZ ;  B8GYT1, GLMU_CAUCN ;
DR   Q9A5Z3, GLMU_CAUCR ;  B3PIS4, GLMU_CELJU ;  Q1QSD2, GLMU_CHRSD ;
DR   Q7MBG1, GLMU_CHRVO ;  A8ACN3, GLMU_CITK8 ;  B0RHI9, GLMU_CLAMS ;
DR   Q97E92, GLMU_CLOAB ;  A7FPK2, GLMU_CLOB1 ;  C3KWA1, GLMU_CLOB6 ;
DR   A6LPJ1, GLMU_CLOB8 ;  B2UXS6, GLMU_CLOBA ;  B2TI07, GLMU_CLOBB ;
DR   A5I7S0, GLMU_CLOBH ;  C1FNF1, GLMU_CLOBJ ;  B1IH02, GLMU_CLOBK ;
DR   A7GJD9, GLMU_CLOBL ;  B1KTE7, GLMU_CLOBM ;  Q181B4, GLMU_CLOD6 ;
DR   B9DY47, GLMU_CLOK1 ;  A5N4I5, GLMU_CLOK5 ;  A0PXK8, GLMU_CLONN ;
DR   Q0TMG3, GLMU_CLOP1 ;  Q8XHJ3, GLMU_CLOPE ;  Q0SQ61, GLMU_CLOPS ;
DR   Q899I9, GLMU_CLOTE ;  A3DIP9, GLMU_CLOTH ;  Q47UE0, GLMU_COLP3 ;
DR   C3PF87, GLMU_CORA7 ;  Q6NI74, GLMU_CORDI ;  Q8FQV1, GLMU_COREF ;
DR   A4QCS3, GLMU_CORGB ;  Q8NRU8, GLMU_CORGL ;  Q4JU42, GLMU_CORJK ;
DR   B6J965, GLMU_COXB1 ;  B6J2E2, GLMU_COXB2 ;  A9KBF4, GLMU_COXBN ;
DR   A9NBD3, GLMU_COXBR ;  Q83AF3, GLMU_COXBU ;  Q0KF07, GLMU_CUPNH ;
DR   Q476S2, GLMU_CUPPJ ;  B2AGH8, GLMU_CUPTR ;  B8HXB5, GLMU_CYAP4 ;
DR   B7KIE0, GLMU_CYAP7 ;  B7JVE8, GLMU_CYAP8 ;  Q47JK2, GLMU_DECAR ;
DR   Q1IWX3, GLMU_DEIGD ;  Q9RW61, GLMU_DEIRA ;  B1I194, GLMU_DESAP ;
DR   Q313W4, GLMU_DESDG ;  B8FY55, GLMU_DESHD ;  Q251V1, GLMU_DESHY ;
DR   Q6AMF9, GLMU_DESPS ;  A4J0P6, GLMU_DESRM ;  Q728D5, GLMU_DESVH ;
DR   B8DKH2, GLMU_DESVM ;  A1VAZ5, GLMU_DESVV ;  A5EXL2, GLMU_DICNV ;
DR   A8LIS2, GLMU_DINSH ;  A7ZTU1, GLMU_ECO24 ;  B7UMJ5, GLMU_ECO27 ;
DR   B7MGF0, GLMU_ECO45 ;  B7L878, GLMU_ECO55 ;  P0ACC8, GLMU_ECO57 ;
DR   B5YXD4, GLMU_ECO5E ;  B7NR32, GLMU_ECO7I ;  B7N2G9, GLMU_ECO81 ;
DR   B7M586, GLMU_ECO8A ;  C4ZZ08, GLMU_ECOBW ;  B1X9V8, GLMU_ECODH ;
DR   A8A6J2, GLMU_ECOHS ;  A1AHR2, GLMU_ECOK1 ;  Q0TAX9, GLMU_ECOL5 ;
DR   Q8FBT3, GLMU_ECOL6 ;  B1IX08, GLMU_ECOLC ;  P0ACC7, GLMU_ECOLI ;
DR   B7NF46, GLMU_ECOLU ;  B6I3W7, GLMU_ECOSE ;  B1LL57, GLMU_ECOSM ;
DR   Q1R4K5, GLMU_ECOUT ;  C5BF42, GLMU_EDWI9 ;  A4WGF8, GLMU_ENT38 ;
DR   Q839U1, GLMU_ENTFA ;  A7MMY0, GLMU_ENTS8 ;  Q6CYJ8, GLMU_ERWCT ;
DR   B2VCC9, GLMU_ERWT9 ;  B7LK74, GLMU_ESCF3 ;  B1YGP5, GLMU_EXIS2 ;
DR   C4KZV1, GLMU_EXISA ;  A7HKM7, GLMU_FERNB ;  B0TZM4, GLMU_FRAP2 ;
DR   Q2J5Y1, GLMU_FRASC ;  Q14J62, GLMU_FRAT1 ;  A7NAF3, GLMU_FRATF ;
DR   Q2A4X7, GLMU_FRATH ;  B2SFB5, GLMU_FRATM ;  A0Q565, GLMU_FRATN ;
DR   Q0BN96, GLMU_FRATO ;  Q5NHR0, GLMU_FRATT ;  A4IZM7, GLMU_FRATW ;
DR   Q8RHM3, GLMU_FUSNN ;  Q5L3V0, GLMU_GEOKA ;  B3E414, GLMU_GEOLS ;
DR   Q39ZH2, GLMU_GEOMG ;  B9M701, GLMU_GEOSF ;  Q74GH5, GLMU_GEOSL ;
DR   C5D371, GLMU_GEOSW ;  A4IJC6, GLMU_GEOTN ;  A5GDL4, GLMU_GEOUR ;
DR   Q7NNG8, GLMU_GLOVI ;  A9HI46, GLMU_GLUDA ;  Q5FUY6, GLMU_GLUOX ;
DR   Q0BSR5, GLMU_GRABC ;  Q7VLE6, GLMU_HAEDU ;  Q4QMS5, GLMU_HAEI8 ;
DR   A5UE94, GLMU_HAEIE ;  A5UHD3, GLMU_HAEIG ;  P43889, GLMU_HAEIN ;
DR   B8F3K4, GLMU_HAEPS ;  Q0I1G0, GLMU_HAES1 ;  B0UW09, GLMU_HAES2 ;
DR   Q2S6P3, GLMU_HAHCH ;  A1WZS9, GLMU_HALHL ;  C4K351, GLMU_HAMD5 ;
DR   Q17XI1, GLMU_HELAH ;  Q7VIB6, GLMU_HELHP ;  B0TBA0, GLMU_HELMI ;
DR   B6JLS1, GLMU_HELP2 ;  Q1CTI8, GLMU_HELPH ;  Q9ZLF6, GLMU_HELPJ ;
DR   O25393, GLMU_HELPY ;  A4G9W6, GLMU_HERAR ;  B4U648, GLMU_HYDS0 ;
DR   Q0C4B0, GLMU_HYPNA ;  Q5QZH4, GLMU_IDILO ;  A6T3N4, GLMU_JANMA ;
DR   Q28MG0, GLMU_JANSC ;  A6W6V0, GLMU_KINRD ;  B5XZM7, GLMU_KLEP3 ;
DR   A6TG34, GLMU_KLEP7 ;  C5CFS2, GLMU_KOSOT ;  Q5FMG0, GLMU_LACAC ;
DR   Q03T39, GLMU_LACBA ;  Q1GBQ8, GLMU_LACDA ;  Q04C57, GLMU_LACDB ;
DR   B2GFE2, GLMU_LACF3 ;  Q046K2, GLMU_LACGA ;  A8YX58, GLMU_LACH4 ;
DR   Q74LH7, GLMU_LACJO ;  Q9CEF8, GLMU_LACLA ;  A2RMV7, GLMU_LACLM ;
DR   Q02WW6, GLMU_LACLS ;  Q88Z86, GLMU_LACPL ;  A5VI16, GLMU_LACRD ;
DR   B2G5J5, GLMU_LACRJ ;  Q1WV55, GLMU_LACS1 ;  Q38V29, GLMU_LACSS ;
DR   Q1MQ72, GLMU_LAWIP ;  Q5X112, GLMU_LEGPA ;  A5II48, GLMU_LEGPC ;
DR   Q5ZRK6, GLMU_LEGPH ;  Q5WST8, GLMU_LEGPL ;  Q6ADP6, GLMU_LEIXX ;
DR   Q92F69, GLMU_LISIN ;  C1KYD1, GLMU_LISMC ;  Q724L5, GLMU_LISMF ;
DR   B8DGM7, GLMU_LISMH ;  Q8YAD4, GLMU_LISMO ;  A0AF03, GLMU_LISW6 ;
DR   Q2W7U1, GLMU_MAGSA ;  Q65R54, GLMU_MANSM ;  A1U7H2, GLMU_MARAV ;
DR   Q0AR24, GLMU_MARMM ;  A6VTC6, GLMU_MARMS ;  Q11HG1, GLMU_MESSB ;
DR   A6UUQ4, GLMU_META3 ;  Q60CR2, GLMU_METCA ;  Q1GXN2, GLMU_METFK ;
DR   Q58501, GLMU_METJA ;  A4FX98, GLMU_METM5 ;  A6VG23, GLMU_METM7 ;
DR   Q6LYB5, GLMU_METMP ;  A2SD80, GLMU_METPP ;  A6UP85, GLMU_METVS ;
DR   B0JJ82, GLMU_MICAN ;  C5C9D1, GLMU_MICLC ;  Q2RMC5, GLMU_MOOTA ;
DR   A0QBW9, GLMU_MYCA1 ;  Q7VF00, GLMU_MYCBO ;  A1KHF6, GLMU_MYCBP ;
DR   C1AM09, GLMU_MYCBT ;  A4T6M7, GLMU_MYCGI ;  B8ZU67, GLMU_MYCLB ;
DR   Q9CD44, GLMU_MYCLE ;  B2HDJ0, GLMU_MYCMM ;  Q741V3, GLMU_MYCPA ;
DR   A0R3C7, GLMU_MYCS2 ;  A3Q5G5, GLMU_MYCSJ ;  A1UL17, GLMU_MYCSK ;
DR   Q1B431, GLMU_MYCSS ;  A5U161, GLMU_MYCTA ;  P96382, GLMU_MYCTU ;
DR   A0PW60, GLMU_MYCUA ;  A1TEF5, GLMU_MYCVP ;  Q1DCI1, GLMU_MYXXD ;
DR   B9LAA1, GLMU_NAUPA ;  Q5F577, GLMU_NEIG1 ;  Q50986, GLMU_NEIGO ;
DR   A9LZT7, GLMU_NEIM0 ;  Q9JWN3, GLMU_NEIMA ;  Q9K1P3, GLMU_NEIMB ;
DR   A1KR65, GLMU_NEIMF ;  Q0AJA8, GLMU_NITEC ;  Q82XP7, GLMU_NITEU ;
DR   Q1QME9, GLMU_NITHX ;  Q2YCA1, GLMU_NITMU ;  Q3J6N3, GLMU_NITOC ;
DR   A6Q403, GLMU_NITSB ;  Q3SRP6, GLMU_NITWN ;  Q5YQ11, GLMU_NOCFA ;
DR   B2IU73, GLMU_NOSP7 ;  Q8YQB2, GLMU_NOSS1 ;  Q2G929, GLMU_NOVAD ;
DR   Q8CXP9, GLMU_OCEIH ;  A6X546, GLMU_OCHA4 ;  Q04DS4, GLMU_OENOB ;
DR   B6JFB2, GLMU_OLICO ;  A1AZN6, GLMU_PARDP ;  A7HXP0, GLMU_PARL1 ;
DR   Q9CK29, GLMU_PASMU ;  C6DJH5, GLMU_PECCP ;  Q03HD2, GLMU_PEDPA ;
DR   Q3A0D8, GLMU_PELCD ;  A1ALB2, GLMU_PELPD ;  A5D662, GLMU_PELTS ;
DR   Q7NA96, GLMU_PHOLL ;  Q6LLH1, GLMU_PHOPR ;  A1VJM6, GLMU_POLNA ;
DR   Q12FR3, GLMU_POLSJ ;  Q6AAD3, GLMU_PROAC ;  A3PBY5, GLMU_PROM0 ;
DR   A8G3X7, GLMU_PROM2 ;  A9BAV8, GLMU_PROM4 ;  A2BVS4, GLMU_PROM5 ;
DR   Q31BS3, GLMU_PROM9 ;  Q7VBP2, GLMU_PROMA ;  B4F0E9, GLMU_PROMH ;
DR   Q7V8F2, GLMU_PROMM ;  Q7V274, GLMU_PROMP ;  A2BQ92, GLMU_PROMS ;
DR   Q46LT9, GLMU_PROMT ;  Q48BG7, GLMU_PSE14 ;  Q15P09, GLMU_PSEA6 ;
DR   A6VF30, GLMU_PSEA7 ;  B7V789, GLMU_PSEA8 ;  Q02DF6, GLMU_PSEAB ;
DR   Q9HT22, GLMU_PSEAE ;  Q1I2I9, GLMU_PSEE4 ;  Q4K3B1, GLMU_PSEF5 ;
DR   C3K1E4, GLMU_PSEFS ;  Q3IK30, GLMU_PSEHT ;  A4Y185, GLMU_PSEMY ;
DR   A5WBA1, GLMU_PSEP1 ;  Q3K443, GLMU_PSEPF ;  B0KRA6, GLMU_PSEPG ;
DR   Q88BX6, GLMU_PSEPK ;  Q87TT6, GLMU_PSESM ;  Q4ZL26, GLMU_PSEU2 ;
DR   A4VS60, GLMU_PSEU5 ;  Q4FPY8, GLMU_PSYA2 ;  Q1Q830, GLMU_PSYCK ;
DR   A1SZH6, GLMU_PSYIN ;  A5WHT0, GLMU_PSYWF ;  Q1LS04, GLMU_RALME ;
DR   B2UD47, GLMU_RALPJ ;  Q8Y304, GLMU_RALSO ;  B3PZN3, GLMU_RHIE6 ;
DR   Q2K8G2, GLMU_RHIEC ;  Q1MGP8, GLMU_RHIL3 ;  Q98LX2, GLMU_RHILO ;
DR   B5ZP51, GLMU_RHILW ;  Q92PS3, GLMU_RHIME ;  C3MCF7, GLMU_RHISN ;
DR   Q21ZH9, GLMU_RHOFD ;  C1AY41, GLMU_RHOOB ;  Q2IW53, GLMU_RHOP2 ;
DR   Q07MW2, GLMU_RHOP5 ;  Q6N6F8, GLMU_RHOPA ;  Q214N1, GLMU_RHOPB ;
DR   Q136Z3, GLMU_RHOPS ;  B3QIT8, GLMU_RHOPT ;  Q2RPX0, GLMU_RHORT ;
DR   Q3J3H0, GLMU_RHOS4 ;  A4WU43, GLMU_RHOS5 ;  Q0S4N3, GLMU_RHOSR ;
DR   Q163N8, GLMU_ROSDO ;  Q1AXL7, GLMU_RUBXD ;  A1AXS8, GLMU_RUTMC ;
DR   Q21DL5, GLMU_SACD2 ;  B5EYZ3, GLMU_SALA4 ;  A9MJS2, GLMU_SALAR ;
DR   Q57HY1, GLMU_SALCH ;  B5FN29, GLMU_SALDC ;  B5QUS1, GLMU_SALEP ;
DR   B5RFW6, GLMU_SALG2 ;  B4TAW9, GLMU_SALHS ;  B4SYC8, GLMU_SALNS ;
DR   Q5PKV8, GLMU_SALPA ;  A9MXA3, GLMU_SALPB ;  B5BIN3, GLMU_SALPK ;
DR   B4TN27, GLMU_SALSV ;  Q8Z2Q3, GLMU_SALTI ;  Q8ZKX0, GLMU_SALTY ;
DR   A8G7N0, GLMU_SERP5 ;  A1SBT8, GLMU_SHEAM ;  B8EDU8, GLMU_SHEB2 ;
DR   A3DAR2, GLMU_SHEB5 ;  A6WUI8, GLMU_SHEB8 ;  A9KX04, GLMU_SHEB9 ;
DR   Q12HQ5, GLMU_SHEDO ;  Q07VU6, GLMU_SHEFN ;  B0TQE8, GLMU_SHEHH ;
DR   A3QJQ7, GLMU_SHELP ;  Q8E8C2, GLMU_SHEON ;  A8HAG0, GLMU_SHEPA ;
DR   A4YCH6, GLMU_SHEPC ;  B8CVU0, GLMU_SHEPW ;  A0L2S6, GLMU_SHESA ;
DR   A8G1W3, GLMU_SHESH ;  Q0HD81, GLMU_SHESM ;  Q0HPG3, GLMU_SHESR ;
DR   A1RQA8, GLMU_SHESW ;  B1KQ31, GLMU_SHEWM ;  B2TUP5, GLMU_SHIB3 ;
DR   Q31UN0, GLMU_SHIBS ;  Q329R9, GLMU_SHIDS ;  Q0SYU6, GLMU_SHIF8 ;
DR   Q83IY3, GLMU_SHIFL ;  Q3YVN4, GLMU_SHISS ;  Q5LPQ1, GLMU_SILPO ;
DR   Q1GIQ5, GLMU_SILST ;  A6U9C1, GLMU_SINMW ;  Q2NQ84, GLMU_SODGM ;
DR   Q01YD9, GLMU_SOLUE ;  A9FSV7, GLMU_SORC5 ;  Q1GTD8, GLMU_SPHAL ;
DR   A5VF26, GLMU_SPHWW ;  Q2FJE2, GLMU_STAA3 ;  Q2G0S3, GLMU_STAA8 ;
DR   Q2YVU6, GLMU_STAAB ;  Q5HIH6, GLMU_STAAC ;  Q99WA4, GLMU_STAAM ;
DR   Q7A7B4, GLMU_STAAN ;  Q6GJH2, GLMU_STAAR ;  Q6GBY9, GLMU_STAAS ;
DR   Q8NXZ7, GLMU_STAAW ;  B9DLD6, GLMU_STACT ;  Q937Z1, GLMU_STAEP ;
DR   Q5HRQ6, GLMU_STAEQ ;  Q8CMT0, GLMU_STAES ;  Q4L3F6, GLMU_STAHJ ;
DR   Q49V08, GLMU_STAS1 ;  Q3JZY6, GLMU_STRA1 ;  Q8E409, GLMU_STRA3 ;
DR   Q8DYE6, GLMU_STRA5 ;  Q82HE8, GLMU_STRAW ;  Q8CJX6, GLMU_STRCO ;
DR   A8AY88, GLMU_STRGC ;  B1VUI7, GLMU_STRGG ;  B4SJR6, GLMU_STRM5 ;
DR   B2FHY5, GLMU_STRMK ;  Q8DSX2, GLMU_STRMU ;  Q9A163, GLMU_STRP1 ;
DR   Q04KU2, GLMU_STRP2 ;  P0DB62, GLMU_STRP3 ;  B5E4A8, GLMU_STRP4 ;
DR   Q5XDJ2, GLMU_STRP6 ;  C1C6W6, GLMU_STRP7 ;  Q8P286, GLMU_STRP8 ;
DR   Q1JD75, GLMU_STRPB ;  Q1JN46, GLMU_STRPC ;  Q1J847, GLMU_STRPF ;
DR   A2RG45, GLMU_STRPG ;  B1IBE8, GLMU_STRPI ;  Q48UZ1, GLMU_STRPM ;
DR   Q97R46, GLMU_STRPN ;  P0DB63, GLMU_STRPQ ;  B5XK49, GLMU_STRPZ ;
DR   Q8DQ18, GLMU_STRR6 ;  A4W313, GLMU_STRS2 ;  A3CPC4, GLMU_STRSV ;
DR   A4VWR1, GLMU_STRSY ;  Q8GQP7, GLMU_STRSZ ;  Q5M0U2, GLMU_STRT1 ;
DR   Q5M5C8, GLMU_STRT2 ;  Q03LQ1, GLMU_STRTD ;  B9DRD5, GLMU_STRU0 ;
DR   C1CDY3, GLMU_STRZJ ;  C1CRR4, GLMU_STRZT ;  Q30RT9, GLMU_SULDN ;
DR   A6QBC4, GLMU_SULNB ;  Q67JC8, GLMU_SYMTH ;  Q31RJ9, GLMU_SYNE7 ;
DR   Q2JVA4, GLMU_SYNJA ;  Q2JII9, GLMU_SYNJB ;  B1XLT6, GLMU_SYNP2 ;
DR   Q5N2Q6, GLMU_SYNP6 ;  Q7U7I0, GLMU_SYNPX ;  A5GT42, GLMU_SYNR3 ;
DR   Q0I9Y4, GLMU_SYNS3 ;  Q3AVF3, GLMU_SYNS9 ;  Q3AKJ8, GLMU_SYNSC ;
DR   Q0B0S9, GLMU_SYNWW ;  Q55504, GLMU_SYNY3 ;  B7IFM4, GLMU_THEAB ;
DR   Q8DLT5, GLMU_THEEB ;  Q47SW5, GLMU_THEFY ;  A8F4D4, GLMU_THELT ;
DR   A6LJD6, GLMU_THEM4 ;  Q9X1W4, GLMU_THEMA ;  A5ILV3, GLMU_THEP1 ;
DR   B0KBF5, GLMU_THEP3 ;  B1LBD9, GLMU_THESQ ;  Q72LP1, GLMU_THET2 ;
DR   Q5SLA8, GLMU_THET8 ;  Q8R752, GLMU_THETN ;  B5YHS4, GLMU_THEYD ;
DR   Q31DM2, GLMU_THICR ;  Q3SF69, GLMU_THIDA ;  B8GRB6, GLMU_THISH ;
DR   C4L8R0, GLMU_TOLAT ;  Q118R6, GLMU_TRIEI ;  Q83NE5, GLMU_TROW8 ;
DR   Q83GR0, GLMU_TROWT ;  A5CVK9, GLMU_VESOH ;  A5F461, GLMU_VIBC3 ;
DR   Q9KNH7, GLMU_VIBCH ;  C3LSI7, GLMU_VIBCM ;  Q5E1N9, GLMU_VIBF1 ;
DR   B5FCY9, GLMU_VIBFM ;  A7N0Z7, GLMU_VIBHB ;  Q87KB0, GLMU_VIBPA ;
DR   Q8DDG6, GLMU_VIBVU ;  Q7MGI2, GLMU_VIBVY ;  Q8D3J1, GLMU_WIGBR ;
DR   Q73IM4, GLMU_WOLPM ;  Q7M7T9, GLMU_WOLSU ;  Q5GTJ4, GLMU_WOLTR ;
DR   Q8PGH2, GLMU_XANAC ;  Q3BP20, GLMU_XANC5 ;  Q4UQF8, GLMU_XANC8 ;
DR   B0RWB8, GLMU_XANCB ;  Q8PCZ1, GLMU_XANCP ;  Q2P7P9, GLMU_XANOM ;
DR   Q5H4Y0, GLMU_XANOR ;  A7INP6, GLMU_XANP2 ;  B2I874, GLMU_XYLF2 ;
DR   Q9PE88, GLMU_XYLFA ;  B0U595, GLMU_XYLFM ;  Q87E93, GLMU_XYLFT ;
DR   A1JTC3, GLMU_YERE8 ;  A7FPD8, GLMU_YERP3 ;  Q1C097, GLMU_YERPA ;
DR   B2K849, GLMU_YERPB ;  Q8Z9S7, GLMU_YERPE ;  Q1CCH7, GLMU_YERPN ;
DR   A4TSJ5, GLMU_YERPP ;  Q663R0, GLMU_YERPS ;  B1JRN4, GLMU_YERPY ;
DR   Q5NQ83, GLMU_ZYMMO ;
//
ID   2.3.1.158
DE   Phospholipid:diacylglycerol acyltransferase.
AN   PDAT.
CA   Phospholipid + 1,2-diacylglycerol = lysophospholipid + triacylglycerol.
CC   -!- This enzyme differs from EC 2.3.1.20 by synthesising triacylglycerol
CC       using an acyl-CoA-independent mechanism.
CC   -!- The specificity of the enzyme for the acyl group in the phospholipid
CC       varies with species, e.g., the enzyme from castor bean (Ricinus
CC       communis) preferentially incorporates vernoloyl (12,13-epoxyoctadec-
CC       9-enoyl) groups into triacylglycerol, whereas that from the hawk's
CC       beard (Crepis palaestina) incorporates both ricinoleoyl
CC       (12-hydroxyoctadec-9-enoyl) and vernoloyl groups.
CC   -!- The enzyme from the yeast Saccharomyces cerevisiae specifically
CC       transfers acyl groups from the sn-2 position of the phospholipid to
CC       diacylglycerol, thus forming an sn-1-lysophospholipid.
DR   Q9FNA9, PDAT1_ARATH;  Q9FYC7, PDAT2_ARATH;  O94680, PDAT_SCHPO ;
DR   P40345, PDAT_YEAST ;
//
ID   2.3.1.159
DE   Acridone synthase.
CA   3 malonyl-CoA + N-methylanthraniloyl-CoA = 4 CoA + 1,3-dihydroxy-N-
CA   methylacridone + 3 CO(2).
PR   PROSITE; PDOC00403;
DR   Q9FSC0, ACS2_RUTGR ;  Q9FSC2, ACS3_RUTGR ;  Q9FSC1, ACS4_RUTGR ;
//
ID   2.3.1.160
DE   Vinorine synthase.
CA   Acetyl-CoA + 16-epivellosimine = CoA + vinorine.
CC   -!- The reaction proceeds in two stages.
CC   -!- The indole nitrogen of 16-epivellosimine interacts with its aldehyde
CC       group giving an hydroxy-substituted new ring.
CC   -!- This alcohol is then acetylated.
CC   -!- Also acts on gardneral (11-methoxy-16-epivellosimine).
CC   -!- Generates the ajmalan skeleton, which forms part of the route to
CC       ajmaline.
DR   Q70PR7, VINSY_RAUSE;
//
ID   2.3.1.161
DE   Lovastatin nonaketide synthase.
CA   Acetyl-CoA + 8 malonyl-CoA + 11 NADPH + S-adenosyl-L-methionine =
CA   dihydromonacolin L + 9 CoA + 8 CO(2) + 11 NADP(+) + S-adenosyl-L-
CA   homocysteine + 6 H(2)O.
CC   -!- The microbial enzyme is a multi-functional protein catalyzing many of
CC       the chain building reactions of EC 2.3.1.85 as well as a reductive
CC       methylation and a Diels-Alder reaction.
PR   PROSITE; PDOC00529;
DR   Q9Y8A5, LNKS_ASPTE ;  Q0C8M3, LNKS_ASPTN ;
//
ID   2.3.1.162
DE   Taxadien-5-alpha-ol O-acetyltransferase.
AN   Taxa-4(20),11(12)-dien-5-alpha-ol O-acetyltransferase.
AN   Taxadienol acetyltransferase.
CA   Acetyl-CoA + taxa-4(20),11-dien-5-alpha-ol = CoA + taxa-4(20),11-dien-5-
CA   alpha-yl acetate.
CC   -!- This is the third enzyme in the biosynthesis of the diterpenoid
CC       antineoplastic drug taxol (paclitaxel), which is widely used in the
CC       treatment of carcinomas, sarcomas and melanomas.
DR   Q9M6F0, T5AT_TAXCU ;  Q8S9G6, T5AT_TAXWC ;
//
ID   2.3.1.163
DE   10-hydroxytaxane O-acetyltransferase.
AN   Acetyl coenzyme A:10-hydroxytaxane O-acetyltransferase.
CA   Acetyl-CoA + 10-desacetyltaxuyunnanin C = CoA + taxuyunnanin C.
CC   -!- Acts on a number of related taxane diterpenoids with a free 10-beta-
CC       hydroxy group.
CC   -!- May be identical to EC 2.3.1.167.
//
ID   2.3.1.164
DE   Isopenicillin-N N-acyltransferase.
AN   Acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase.
AN   Acyl-coenzyme A:isopenicillin N acyltransferase.
AN   Isopenicillin N:acyl-CoA acyltransferase.
CA   Phenylacetyl-CoA + isopenicillin N + H(2)O = CoA + penicillin G + L-2-
CA   aminohexanedioate.
CC   -!- Proceeds by a two stage mechanism via 6-aminopenicillanic acid.
CC   -!- Different from EC 3.5.1.11.
DR   P21133, AAAA_EMENI ;  P15802, AAAA_PENCH ;
//
ID   2.3.1.165
DE   6-methylsalicylic acid synthase.
AN   6-MSAS.
AN   MSAS.
CA   Acetyl-CoA + 3 malonyl-CoA + NADPH = 6-methylsalicylate + 4 CoA + 3 CO(2)
CA   + NADP(+).
CC   -!- A multienzyme complex with a 4'-phosphopantetheine prosthetic group
CC       on the acyl carrier protein.
CC   -!- It has a similar sequence to vertebrate type I fatty acid synthase.
CC   -!- Acetoacetyl-CoA can also act as a starter molecule.
DR   P22367, MSAS_PENPA ;
//
ID   2.3.1.166
DE   2-alpha-hydroxytaxane 2-O-benzoyltransferase.
AN   2-debenzoyl-7,13-diacetylbaccatin III-2-O-benzoyl transferase.
AN   Benzoyl-CoA:taxane 2-alpha-O-benzoyltransferase.
CA   Benzoyl-CoA + 10-deacetyl-2-debenzoylbaccatin III = CoA +
CA   10-deacetylbaccatin III.
CC   -!- The enzyme was studied using the semisynthetic substrate 2-debenzoyl-
CC       7,13-diacetylbaccatin III.
CC   -!- It will not acylate the hydroxy group at 1-beta, 7-beta, 10-beta or
CC       13-alpha of 10-deacetylbaccatin III, or at 2-alpha or 5-alpha of
CC       taxa-4(20),11-diene-2-alpha,5-alpha-diol.
DR   Q9FPW3, DBBT_TAXCU ;
//
ID   2.3.1.167
DE   10-deacetylbaccatin III 10-O-acetyltransferase.
CA   Acetyl-CoA + 10-deacetylbaccatin III = CoA + baccatin III.
CC   -!- The enzyme will not acylate the hydroxy group at 1-beta, 7-beta,
CC       13-alpha of 10-deacetylbaccatin III, or at 5-alpha of taxa-4(20),
CC       11-dien-5-alpha-ol.
CC   -!- May be identical to EC 2.3.1.163.
DR   Q9M6E2, DBAT_TAXCU ;
//
ID   2.3.1.168
DE   Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase.
AN   Dihydrolipoyl transacylase.
CA   2-methylpropanoyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme
CA   N(6)-(S-(2-methylpropanoyl)dihydrolipoyl)lysine.
CC   -!- A multimer (24-mer) of this enzyme forms the core of the multienzyme
CC       3-methyl-2-oxobutanoate dehydrogenase complex, and binds tightly both
CC       EC 1.2.4.4 and EC 1.8.1.4.
CC   -!- The lipoyl group of this enzyme is reductively 2-methylpropanoylated
CC       by EC 1.2.4.4, and the only observed direction catalyzed by
CC       EC 2.3.1.168 is that where this 2-methylpropanoyl is passed to
CC       coenzyme A.
CC   -!- In addition to the 2-methylpropanoyl group, formed when EC 1.2.4.4
CC       acts on the oxoacid that corresponds with valine, this enzyme also
CC       transfers the 3-methylbutanoyl and S-2-methylbutanoyl groups, donated
CC       to it when EC 1.2.4.4 acts on the oxo acids corresponding with
CC       leucine and isoleucine.
DR   P37942, ODB2_BACSU ;  P11181, ODB2_BOVIN ;  P11182, ODB2_HUMAN ;
DR   P53395, ODB2_MOUSE ;  Q9I1M0, ODB2_PSEAE ;  P09062, ODB2_PSEPU ;
//
ID   2.3.1.169
DE   CO-methylating acetyl-CoA synthase.
AN   ACS.
CA   Acetyl-CoA + corrinoid protein = CO + methylcorrinoid protein + CoA.
CF   Iron-sulfur; Nickel.
CC   -!- Also catalyzes exchange reactions of carbon between C-1 of acetyl-CoA
CC       and CO, and between C-2 of acetyl-CoA and methyl corrinoid protein.
CC   -!- Involved, together with EC 1.2.7.4, in the synthesis of acetyl-CoA
CC       from CO(2) and H(2).
CC   -!- To follow its stoichiometry, the reaction can be written as: CH(3)-
CC       CO-S-CoA + protein Co(+) + H(+) = CO + protein Co(2+)-CH(3) + HS-CoA.
DR   P27988, DCMA_MOOTH ;
//
ID   2.3.1.170
DE   6'-deoxychalcone synthase.
CA   3 malonyl-CoA + 4-coumaroyl-CoA + NADPH = 4 CoA + isoliquiritigenin +
CA   3 CO(2) + NADP(+) + H(2)O.
CC   -!- Isoliquiritigenin is the precursor of liquiritigenin,
CC       a 5-deoxyflavanone.
PR   PROSITE; PDOC00061;
DR   P26690, 6DCS_SOYBN ;
//
ID   2.3.1.171
DE   Anthocyanin 6''-O-malonyltransferase.
AN   3MaT.
AN   Malonyl-coenzymeA:anthocyanidin-3-O-beta-D-glucoside 6''-O-
AN   malonyltransferase.
CA   Malonyl-CoA + an anthocyanidin 3-O-beta-D-glucoside = CoA +
CA   an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside).
CC   -!- Acts on pelargonidin 3-O-glucoside in dahlia (Dahlia variabilis),
CC       delphinidin 3-O-glucoside, and on cyanidin 3-O-glucoside in
CC       transgenic petunia (Petunia hybrida).
DR   Q8GSN8, 3MAT_DAHPI ;
//
ID   2.3.1.172
DE   Anthocyanin 5-O-glucoside 6'''-O-malonyltransferase.
AN   Ss5MaT1.
CA   Malonyl-CoA + pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-
CA   glucoside = CoA + 4'''-demalonylsalvianin.
CC   -!- Specific for the penultimate step in salvianin biosynthesis.
CC   -!- The enzyme also catalyzes the malonylation of shisonin to
CC       malonylshisonin (cyanidin 3-O-(6''-O-p-coumaryl-beta-D-glucoside)-5-
CC       (6'''-O-malonyl-beta-D-glucoside)).
CC   -!- The compounds 4'''-demalonylsalvianin, salvianin, pelargonidin 3,5-
CC       diglucoside and delphinidin 3,5-diglucoside cannot act as substrates.
DR   Q8W1W9, 5MAT1_SALSN;
//
ID   2.3.1.173
DE   Flavonol-3-O-triglucoside O-coumaroyltransferase.
CA   4-coumaroyl-CoA + a flavonol 3-O-(beta-D-glucosyl-(1->2)-beta-D-glucosyl-
CA   (1->2)-beta-D-glucoside) = CoA + a flavonol 3-O-(6-(4-coumaroyl)-beta-D-
CA   glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside).
CC   -!- Acylates kaempferol 3-O-triglucoside on the terminal glucosyl unit,
CC       almost certainly at C-6.
//
ID   2.3.1.174
DE   3-oxoadipyl-CoA thiolase.
AN   Beta-ketoadipyl-CoA thiolase.
CA   Succinyl-CoA + acetyl-CoA = CoA + 3-oxoadipyl-CoA.
DR   Q43935, CATF_ACIAD ;  P0C7L2, PAAJ_ECOLI ;  P0C7L3, PAAJ_ECOLX ;
DR   Q43974, PCAF_ACIAD ;  Q9I6R0, PCAF_PSEAE ;  Q51956, PCAF_PSEPU ;
DR   Q8VPF1, PCAF_PSESB ;
//
ID   2.3.1.175
DE   Deacetylcephalosporin-C acetyltransferase.
AN   Acetyl coenzyme A:DAC acetyltransferase.
AN   Acetyl-CoA:DAC acetyltransferase.
AN   CPC acetylhydrolase.
AN   DAC acetyltransferase.
AN   DAC-AT.
AN   Deacetylcephalosporin C acetyltransferase.
CA   Acetyl-CoA + deacetylcephalosporin C = CoA + cephalosporin C.
CC   -!- This enzyme catalyzes the final step in the biosynthesis of
CC       cephalosporin C.
DR   P39058, CEFG_CEPAC ;
//
ID   2.3.1.176
DE   Propanoyl-CoA C-acyltransferase.
AN   Peroxisomal thiolase 2.
AN   PTE-2.
AN   SCP(chi).
AN   SCP-X.
AN   Sterol carrier protein-chi.
AN   Sterol carrier protein-X.
CA   3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanoyl-CoA + propanoyl-CoA
CA   = CoA + 3-alpha,7-alpha,12-alpha-trihydroxy-24-oxo-5-beta-cholestanoyl-
CA   CoA.
CC   -!- Also acts on dihydroxy-5-beta-cholestanoyl-CoA and other branched
CC       chain acyl-CoA derivatives.
CC   -!- Catalyzes the penultimate step in the formation of bile acids.
CC   -!- The bile acid moiety is transferred from the acyl-CoA thioester (RCO-
CC       SCoA) to either glycine or taurine (NH(2)R') by EC 2.3.1.65.
PR   PROSITE; PDOC00092;
DR   P07857, NLTP_BOVIN ;  Q07598, NLTP_CHICK ;  P22307, NLTP_HUMAN ;
DR   P32020, NLTP_MOUSE ;  O62742, NLTP_RABIT ;  P11915, NLTP_RAT   ;
//
ID   2.3.1.177
DE   Biphenyl synthase.
AN   BIS.
CA   3 malonyl-CoA + benzoyl-CoA = 4 CoA + 3,5-dihydroxybiphenyl + 4 CO(2).
CC   -!- A polyketide synthase that is involved in the production of the
CC       phytoalexin aucuparin.
CC   -!- 2-hydroxybenzoyl-CoA can also act as substrate but it leads to the
CC       derailment product 2-hydroxybenzoyltriacetic acid lactone.
CC   -!- Uses the same starter substrate as EC 2.3.1.151.
//
ID   2.3.1.178
DE   Diaminobutyrate acetyltransferase.
AN   2,4-diaminobutanoate acetyltransferase.
AN   DAB acetyltransferase.
AN   DABA acetyltransferase.
AN   DABAcT.
AN   Diaminobutyric acid acetyltransferase.
AN   L-2,4-diaminobutanoate acetyltransferase.
AN   L-2,4-diaminobutyrate acetyltransferase.
CA   Acetyl-CoA + L-2,4-diaminobutanoate = CoA + N(4)-acetyl-L-2,4-
CA   diaminobutanoate.
CF   Sodium or potassium.
CC   -!- Ornithine, lysine, aspartate, and alpha-, beta- and gamma-
CC       aminobutanoate cannot act as substrates.
CC   -!- However, acetyl-CoA can be replaced by propanoyl-CoA, although the
CC       reaction proceeds more slowly.
CC   -!- Forms part of the ectoine biosynthesis pathway, the other enzymes
CC       involved being EC 2.6.1.76 and EC 4.2.1.108.
PR   PROSITE; PDOC51186;
DR   Q9KED3, ECTA_BACHD ;  Q9AP35, ECTA_BACPA ;  Q5WL79, ECTA_BACSK ;
DR   Q7WHI7, ECTA_BORBR ;  Q7W980, ECTA_BORPA ;  Q9ZEU8, ECTA_CHRSD ;
DR   O52249, ECTA_HALED ;  O06059, ECTA_MARHA ;  Q4JQJ5, ECTA_METAA ;
DR   Q5YW78, ECTA_NOCFA ;  Q8ESU9, ECTA_OCEIH ;  Q6QUZ0, ECTA_STRAQ ;
DR   Q829L3, ECTA_STRAW ;  Q93RW2, ECTA_STRCO ;  Q9KLC1, ECTA_VIBCH ;
DR   Q87NZ6, ECTA_VIBPA ;  Q6PR33, ECTA_VIRPA ;  Q7M9K3, ECTA_WOLSU ;
//
ID   2.3.1.179
DE   Beta-ketoacyl-acyl-carrier-protein synthase II.
AN   3-oxoacyl-acyl carrier protein synthase I.
AN   Beta-ketoacyl-ACP synthase II.
AN   KAS II.
AN   KASII.
CA   (Z)-hexadec-11-enoyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-
CA   protein] = (Z)-3-oxooctadec-13-enoyl-[acyl-carrier-protein] + CO(2) +
CA   [acyl-carrier-protein].
CC   -!- Involved in the dissociated (or type II) fatty acid biosynthesis
CC       system that occurs in plants and bacteria.
CC   -!- While the substrate specificity of this enzyme is very similar to
CC       that of EC 2.3.1.41, it differs in that palmitoleoyl-ACP is not a
CC       good substrate of EC 2.3.1.41 but is an excellent substrate of this
CC       enzyme.
CC   -!- The fatty-acid composition of Escherichia coli changes as a function
CC       of growth temperature, with the proportion of unsaturated fatty acids
CC       increasing with lower growth temperature.
CC   -!- Controls the temperature-dependent regulation of fatty-acid
CC       composition, with mutants lacking this acivity being deficient in the
CC       elongation of palmitoleate to cis-vaccenate at low temperatures.
PR   PROSITE; PDOC00529;
DR   O34340, FABF_BACSU ;  Q83E37, FABF_COXBU ;  P0AAI7, FABF_ECO57 ;
DR   P0AAI6, FABF_ECOL6 ;  P0AAI5, FABF_ECOLI ;  P56902, FABF_RHIME ;
DR   P0AAI8, FABF_SHIFL ;  Q5HHA1, FABF_STAAC ;  Q99VA6, FABF_STAAM ;
DR   Q7A6F8, FABF_STAAN ;  Q6GIA3, FABF_STAAR ;  Q6GAU2, FABF_STAAS ;
DR   Q5TKS0, FABF_STAAU ;  Q8NXE1, FABF_STAAW ;  P73283, FABF_SYNY3 ;
DR   Q9KQH9, FABF_VIBCH ;  P55338, FABF_VIBHA ;
//
ID   2.3.1.180
DE   Beta-ketoacyl-acyl-carrier-protein synthase III.
AN   3-ketoacyl-acyl carrier protein synthase III.
AN   3-oxoacyl:ACP synthase III.
AN   Beta-ketoacyl (acyl carrier protein) synthase III.
AN   Beta-ketoacyl-ACP synthase III.
AN   Beta-ketoacyl-acyl carrier protein synthase III.
AN   KAS III.
AN   KASIII.
CA   Acetyl-CoA + malonyl-[acyl-carrier-protein] = acetoacetyl-[acyl-carrier-
CA   protein] + CoA + CO(2).
CC   -!- Involved in the dissociated (or type II) fatty-acid biosynthesis
CC       system that occurs in plants and bacteria.
CC   -!- In contrast to EC 2.3.1.41 and EC 2.3.1.179, this enzyme specifically
CC       uses CoA thioesters rather than acyl-ACP as the primer.
CC   -!- In addition to the above reaction, the enzyme can also catalyze the
CC       reaction of EC 2.3.1.38, but to a much lesser extent.
CC   -!- Responsible for initiating both straight- and branched-chain fatty-
CC       acid biosynthesis, with the substrate specificity in an organism
CC       reflecting the fatty-acid composition found in that organism.
CC   -!- For example, Streptococcus pneumoniae, a Gram-positive bacterium,
CC       is able to use both straight- and branched-chain (C4--C6) acyl-CoA
CC       primers whereas Escherichia coli, a Gram-negative organism, uses
CC       primarily short straight-chain acyl CoAs, with a preference for
CC       acetyl-CoA.
DR   Q81JG0, FABH1_BACAN;  Q81GM0, FABH1_BACCR;  Q9K8W9, FABH1_BACHD;
DR   O34746, FABH1_BACSU;  Q8ABI8, FABH1_BACTN;  P49244, FABH1_CUPWR;
DR   Q9RT23, FABH1_DEIRA;  Q88YZ4, FABH1_LACPL;  Q8CPT4, FABH1_STAES;
DR   Q82BB8, FABH1_STRAW;  P72392, FABH1_STRCO;  Q9KQH5, FABH1_VIBCH;
DR   Q87N20, FABH1_VIBPA;  Q8D8G6, FABH1_VIBVU;  Q7M7J9, FABH1_VIBVY;
DR   Q81JF6, FABH2_BACAN;  Q81F42, FABH2_BACCR;  Q9KET5, FABH2_BACHD;
DR   O07600, FABH2_BACSU;  Q8A137, FABH2_BACTN;  P49245, FABH2_CUPWR;
DR   Q9RT22, FABH2_DEIRA;  Q88WG8, FABH2_LACPL;  Q8CUB8, FABH2_STAES;
DR   Q82M29, FABH2_STRAW;  Q9Z4Y5, FABH2_STRCO;  Q9KLJ3, FABH2_VIBCH;
DR   Q87HJ2, FABH2_VIBPA;  Q8D719, FABH2_VIBVU;  Q7M7I3, FABH2_VIBVY;
DR   O54151, FABH3_STRCO;  Q9ZBV4, FABH4_STRCO;  Q9JN82, FABH5_STRCO;
DR   Q9PMZ6, FABHL_CAMJE;  B0CE67, FABH_ACAM1 ;  A9NFF0, FABH_ACHLI ;
DR   B9MDQ9, FABH_ACIET ;  B9JCY9, FABH_AGRRK ;  Q8UG62, FABH_AGRT5 ;
DR   B9JV87, FABH_AGRVS ;  O67185, FABH_AQUAE ;  P49243, FABH_ARATH ;
DR   B6YS41, FABH_AZOPC ;  A1USI9, FABH_BARBK ;  Q6G3K4, FABH_BARHE ;
DR   Q6G000, FABH_BARQU ;  A9IVB4, FABH_BART1 ;  Q7VR18, FABH_BLOFL ;
DR   Q7WD20, FABH_BORBR ;  Q7W5I4, FABH_BORPA ;  A9IIH4, FABH_BORPD ;
DR   Q7VW29, FABH_BORPE ;  Q89K89, FABH_BRAJA ;  B2S524, FABH_BRUA1 ;
DR   Q2YNB9, FABH_BRUA2 ;  Q57DX4, FABH_BRUAB ;  A9MAF6, FABH_BRUC2 ;
DR   C0RIB3, FABH_BRUMB ;  Q8YGH9, FABH_BRUME ;  A5VPV8, FABH_BRUO2 ;
DR   B0CLA2, FABH_BRUSI ;  Q8G1E0, FABH_BRUSU ;  B1JYA0, FABH_BURCC ;
DR   B2JFI9, FABH_BURP8 ;  A4XJW0, FABH_CALS8 ;  Q9PIH1, FABH_CAMJE ;
DR   Q9A8I4, FABH_CAUCR ;  Q820E6, FABH_CHLCV ;  Q9PKF5, FABH_CHLMU ;
DR   Q9Z8P0, FABH_CHLPN ;  Q8KAP2, FABH_CHLTE ;  O84242, FABH_CHLTR ;
DR   Q7NSK7, FABH_CHRVO ;  Q97DA2, FABH_CLOAB ;  C3KWF7, FABH_CLOB6 ;
DR   A6LSC2, FABH_CLOB8 ;  C1FNK7, FABH_CLOBJ ;  B1IHN1, FABH_CLOBK ;
DR   B1KU74, FABH_CLOBM ;  B9DY04, FABH_CLOK1 ;  A5N4E1, FABH_CLOK5 ;
DR   Q8XLH3, FABH_CLOPE ;  Q899P3, FABH_CLOTE ;  B6J8E5, FABH_COXB1 ;
DR   B6J1I6, FABH_COXB2 ;  A9KEA1, FABH_COXBN ;  A9NBY3, FABH_COXBR ;
DR   Q820X0, FABH_COXBU ;  B3R213, FABH_CUPTR ;  C1D0N4, FABH_DEIDV ;
DR   Q1J198, FABH_DEIGD ;  A9BNK6, FABH_DELAS ;  B8FRS6, FABH_DESHD ;
DR   Q24U40, FABH_DESHY ;  B8DJG1, FABH_DESVM ;  A5EXD7, FABH_DICNV ;
DR   A8LLT4, FABH_DINSH ;  P0A6R2, FABH_ECO57 ;  P0A6R1, FABH_ECOL6 ;
DR   B1IUH4, FABH_ECOLC ;  P0A6R0, FABH_ECOLI ;  Q820T1, FABH_ENTFA ;
DR   Q6D690, FABH_ERWCT ;  Q2N925, FABH_ERYLH ;  Q8RGX7, FABH_FUSNN ;
DR   Q7NF35, FABH_GLOVI ;  Q6B945, FABH_GRATL ;  Q7U337, FABH_HAEDU ;
DR   P43711, FABH_HAEIN ;  B0UUZ0, FABH_HAES2 ;  P59813, FABH_HELHP ;
DR   B6JKD5, FABH_HELP2 ;  B5Z9X2, FABH_HELPG ;  Q9ZMN0, FABH_HELPJ ;
DR   B2US32, FABH_HELPS ;  O24994, FABH_HELPY ;  B2GFZ7, FABH_KOCRD ;
DR   Q1GAG1, FABH_LACDA ;  Q04AU8, FABH_LACDB ;  Q9CHG0, FABH_LACLA ;
DR   A5VK78, FABH_LACRD ;  B2G7L1, FABH_LACRJ ;  C1DCE8, FABH_LARHH ;
DR   Q929H1, FABH_LISIN ;  Q71XG3, FABH_LISMF ;  Q8Y573, FABH_LISMO ;
DR   Q11J83, FABH_MESSB ;  Q606L3, FABH_METCA ;  B0JXE2, FABH_MICAN ;
DR   B1MKD7, FABH_MYCA9 ;  P0A575, FABH_MYCBO ;  C1AKL3, FABH_MYCBT ;
DR   B2HRM4, FABH_MYCMM ;  Q73SP5, FABH_MYCPA ;  P0A574, FABH_MYCTU ;
DR   B2A2M5, FABH_NATTJ ;  B4RJI1, FABH_NEIG2 ;  A9M142, FABH_NEIM0 ;
DR   Q9JW56, FABH_NEIMA ;  Q9JXR6, FABH_NEIMB ;  Q82U60, FABH_NITEU ;
DR   Q2YA46, FABH_NITMU ;  Q8Z062, FABH_NOSS1 ;  Q8ERU6, FABH_OCEIH ;
DR   A6X1X8, FABH_OCHA4 ;  Q04DM7, FABH_OENOB ;  Q9CJS8, FABH_PASMU ;
DR   C0QPF4, FABH_PERMH ;  Q7N384, FABH_PHOLL ;  B1XTK6, FABH_POLNS ;
DR   A4SVV4, FABH_POLSQ ;  B2RH63, FABH_PORG3 ;  Q7MAV3, FABH_PORGI ;
DR   P51196, FABH_PORPU ;  P31176, FABH_PORUM ;  Q1XDU1, FABH_PORYE ;
DR   Q7VE55, FABH_PROMA ;  Q7V4F6, FABH_PROMM ;  Q7V3E0, FABH_PROMP ;
DR   A4SCL4, FABH_PROVI ;  B7V4R0, FABH_PSEA8 ;  Q9HYR2, FABH_PSEAE ;
DR   B2U968, FABH_RALPJ ;  Q8Y0J4, FABH_RALSO ;  Q1MIS6, FABH_RHIL3 ;
DR   Q982Z8, FABH_RHILO ;  Q92QT4, FABH_RHIME ;  P59814, FABH_RHOBA ;
DR   P30790, FABH_RHOCA ;  B6IMR5, FABH_RHOCS ;  Q2RTS8, FABH_RHORT ;
DR   Q1RKA5, FABH_RICBR ;  Q92GC1, FABH_RICCN ;  Q4UK49, FABH_RICFE ;
DR   Q9ZCH1, FABH_RICPR ;  B0BV80, FABH_RICRO ;  Q68VX7, FABH_RICTY ;
DR   A7NK75, FABH_ROSCS ;  A5UWI7, FABH_ROSS1 ;  A9MGC9, FABH_SALAR ;
DR   A9N5L3, FABH_SALPB ;  Q8Z7J6, FABH_SALTI ;  O85139, FABH_SALTY ;
DR   Q8EDH1, FABH_SHEON ;  Q83RS8, FABH_SHIFL ;  A6U7Q5, FABH_SINMW ;
DR   Q01QV9, FABH_SOLUE ;  A5VC86, FABH_SPHWW ;  Q07510, FABH_SPIOL ;
DR   A6U089, FABH_STAA2 ;  A5IRG0, FABH_STAA9 ;  Q5HHA2, FABH_STAAC ;
DR   P68795, FABH_STAAM ;  P99159, FABH_STAAN ;  Q6GIA4, FABH_STAAR ;
DR   Q6GAU3, FABH_STAAS ;  A8Z088, FABH_STAAT ;  Q8NXE2, FABH_STAAW ;
DR   Q5HQI2, FABH_STAEQ ;  Q4L4Z3, FABH_STAHJ ;  Q49WB6, FABH_STAS1 ;
DR   P64112, FABH_STRA3 ;  P64113, FABH_STRA5 ;  C0M7U3, FABH_STRE4 ;
DR   B4U1B3, FABH_STREM ;  Q54206, FABH_STRGA ;  A8AYW5, FABH_STRGC ;
DR   Q9F6D4, FABH_STRLI ;  Q8DSN2, FABH_STRMU ;  Q99YD2, FABH_STRP1 ;
DR   P0DB00, FABH_STRP3 ;  B5E7F8, FABH_STRP4 ;  Q5XAE0, FABH_STRP6 ;
DR   C1C5F4, FABH_STRP7 ;  P64115, FABH_STRP8 ;  B1I9L1, FABH_STRPI ;
DR   B8ZLI3, FABH_STRPJ ;  P0A3C5, FABH_STRPN ;  P0DB01, FABH_STRPQ ;
DR   B2ILW2, FABH_STRPS ;  B5XHY5, FABH_STRPZ ;  P0A3C6, FABH_STRR6 ;
DR   C0ME18, FABH_STRS7 ;  B9DVE9, FABH_STRU0 ;  C1CCI2, FABH_STRZJ ;
DR   C1CIR8, FABH_STRZP ;  C1CPS7, FABH_STRZT ;  A6QBY0, FABH_SULNB ;
DR   Q67PG0, FABH_SYMTH ;  P73951, FABH_SYNY3 ;  Q8DKL4, FABH_THEEB ;
DR   Q8R9V7, FABH_THETN ;  B8GSX7, FABH_THISH ;  P64117, FABH_TROW8 ;
DR   P64116, FABH_TROWT ;  C5CSE2, FABH_VARPS ;  Q73GG9, FABH_WOLPM ;
DR   B3CML1, FABH_WOLPP ;  Q8PNE8, FABH_XANAC ;  Q8PBV1, FABH_XANCP ;
DR   Q9PCG4, FABH_XYLFA ;  Q87CL7, FABH_XYLFT ;  Q8ZFT7, FABH_YERPE ;
DR   P20582, PQSD_PSEAE ;
//
ID   2.3.1.181
DE   Lipoyl(octanoyl) transferase.
AN   Lipoate/octanoate transferase.
AN   Lipoyl (octanoyl)-[acyl-carrier-protein]-protein N-lipoyltransferase.
AN   Lipoyl(octanoyl)transferase.
AN   Lipoyltransferase.
AN   Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
CA   Octanoyl-[acyl-carrier-protein] + protein = protein N(6)-(octanoyl)lysine
CA   + [acyl-carrier-protein].
CC   -!- The first committed step in the biosynthesis of lipoyl cofactor.
CC   -!- The lipoyl cofactor is essential for the function of several key
CC       enzymes involved in oxidative metabolism, as it converts apoprotein
CC       into the biologically active holoprotein.
CC   -!- Examples of such lipoylated proteins include pyruvate dehydrogenase
CC       (E(2) domain), 2-oxoglutarate dehydrogenase (E(2) domain),
CC       the branched-chain 2-oxoacid dehydrogenases and the glycine cleavage
CC       system (H protein).
CC   -!- Lipoyl-ACP can also act as a substrate although octanoyl-ACP is
CC       likely to be the true substrate.
CC   -!- The other enzyme involved in the biosynthesis of lipoyl cofactor is
CC       EC 2.8.1.8.
CC   -!- An alternative lipoylation pathway involves EC 2.7.7.63, which can
CC       lipoylate apoproteins using exogenous lipoic acid (or its analogs).
PR   PROSITE; PDOC01017;
DR   Q6L1M2, LIPB1_PICTO;  Q6KZK7, LIPB2_PICTO;  A1TJ32, LIPB_ACIAC ;
DR   Q6F8H3, LIPB_ACIAD ;  Q1IIJ5, LIPB_ACIBL ;  A0LTE0, LIPB_ACIC1 ;
DR   C1F3S1, LIPB_ACIC5 ;  A5G0V3, LIPB_ACICJ ;  A3N2P2, LIPB_ACTP2 ;
DR   B3H2J1, LIPB_ACTP7 ;  B0BRS0, LIPB_ACTPJ ;  A6VM78, LIPB_ACTSZ ;
DR   A0KNA1, LIPB_AERHH ;  A4SJV7, LIPB_AERS4 ;  Q8UF44, LIPB_AGRT5 ;
DR   Q0VN37, LIPB_ALCBS ;  Q0ACA3, LIPB_ALHEH ;  A6TWD0, LIPB_ALKMQ ;
DR   B9KJ95, LIPB_ANAMF ;  Q5PA33, LIPB_ANAMM ;  Q2GL91, LIPB_ANAPZ ;
DR   B9MQ23, LIPB_ANATD ;  Q3M698, LIPB_ANAVT ;  Q9SXP7, LIPB_ARATH ;
DR   Q5P4B9, LIPB_AROAE ;  A1R5J6, LIPB_ARTAT ;  B8HGZ8, LIPB_ARTCA ;
DR   A0JVC9, LIPB_ARTS2 ;  A1K1U6, LIPB_AZOSB ;  C1DMR0, LIPB_AZOVD ;
DR   Q5LDM3, LIPB_BACFN ;  Q64UP8, LIPB_BACFR ;  Q8A8S8, LIPB_BACTN ;
DR   A1UT80, LIPB_BARBK ;  Q6G3I3, LIPB_BARHE ;  Q6FZQ9, LIPB_BARQU ;
DR   A9IVX0, LIPB_BART1 ;  Q1LTM4, LIPB_BAUCH ;  Q6MPS6, LIPB_BDEBA ;
DR   Q2L1E2, LIPB_BORA1 ;  Q7WR01, LIPB_BORBR ;  Q7W223, LIPB_BORPA ;
DR   A9IH67, LIPB_BORPD ;  Q7W0K9, LIPB_BORPE ;  Q89JM6, LIPB_BRAJA ;
DR   A5EL70, LIPB_BRASB ;  A4YT30, LIPB_BRASO ;  Q2YKK8, LIPB_BRUA2 ;
DR   Q577Y8, LIPB_BRUAB ;  C0RLB0, LIPB_BRUMB ;  Q8YC54, LIPB_BRUME ;
DR   Q8FW72, LIPB_BRUSU ;  P57356, LIPB_BUCAI ;  Q8K9Q3, LIPB_BUCAP ;
DR   Q89AL8, LIPB_BUCBP ;  B1YNM7, LIPB_BURA4 ;  Q1BT81, LIPB_BURCA ;
DR   B1JZ91, LIPB_BURCC ;  A0KAV9, LIPB_BURCH ;  Q0BBH9, LIPB_BURCM ;
DR   A9AEG7, LIPB_BURM1 ;  A3MR18, LIPB_BURM7 ;  A2S5Y8, LIPB_BURM9 ;
DR   Q62N15, LIPB_BURMA ;  A1V017, LIPB_BURMS ;  A3NQX5, LIPB_BURP0 ;
DR   Q3JWL3, LIPB_BURP1 ;  A3N575, LIPB_BURP6 ;  B2JC45, LIPB_BURP8 ;
DR   B2SWY4, LIPB_BURPP ;  Q63XX6, LIPB_BURPS ;  Q39CJ1, LIPB_BURS3 ;
DR   Q2T1K6, LIPB_BURTA ;  A4JI72, LIPB_BURVG ;  Q146F2, LIPB_BURXL ;
DR   A4XHV1, LIPB_CALS8 ;  Q9A6B8, LIPB_CAUCR ;  B3PKN9, LIPB_CELJU ;
DR   A9WKF8, LIPB_CHLAA ;  B8G783, LIPB_CHLAD ;  B9LM66, LIPB_CHLSY ;
DR   Q1QXA4, LIPB_CHRSD ;  Q7NTG0, LIPB_CHRVO ;  A8AJH4, LIPB_CITK8 ;
DR   A5CQA0, LIPB_CLAM3 ;  B0RE23, LIPB_CLAMS ;  A5MZJ0, LIPB_CLOK5 ;
DR   Q484R7, LIPB_COLP3 ;  C3PHK5, LIPB_CORA7 ;  Q6NG87, LIPB_CORDI ;
DR   Q8FNP5, LIPB_COREF ;  A4QFS2, LIPB_CORGB ;  Q8NNJ1, LIPB_CORGL ;
DR   Q4JWD9, LIPB_CORJK ;  B6J7S2, LIPB_COXB1 ;  B6IZL5, LIPB_COXB2 ;
DR   A9KFW4, LIPB_COXBN ;  A9NDX7, LIPB_COXBR ;  Q83C64, LIPB_COXBU ;
DR   Q0KFE7, LIPB_CUPNH ;  Q477G6, LIPB_CUPPJ ;  O19898, LIPB_CYACA ;
DR   Q11XW2, LIPB_CYTH3 ;  Q47JD4, LIPB_DECAR ;  Q9RWA5, LIPB_DEIRA ;
DR   A9BPT8, LIPB_DELAS ;  C6BZY6, LIPB_DESAD ;  B8J3G1, LIPB_DESDA ;
DR   Q30XT7, LIPB_DESDG ;  Q6ARJ9, LIPB_DESPS ;  A4J246, LIPB_DESRM ;
DR   Q72DM3, LIPB_DESVH ;  B8DRR1, LIPB_DESVM ;  A1VF78, LIPB_DESVV ;
DR   A5EY93, LIPB_DICNV ;  B5YD73, LIPB_DICT6 ;  B8DZW2, LIPB_DICTD ;
DR   A8LRT6, LIPB_DINSH ;  A7ZJ18, LIPB_ECO24 ;  B7UKS0, LIPB_ECO27 ;
DR   B7MFQ3, LIPB_ECO45 ;  B7L9H4, LIPB_ECO55 ;  P60721, LIPB_ECO57 ;
DR   B5YQI1, LIPB_ECO5E ;  B7NLY9, LIPB_ECO7I ;  B7MRR7, LIPB_ECO81 ;
DR   B7M5F7, LIPB_ECO8A ;  C4ZWB7, LIPB_ECOBW ;  A7ZXQ7, LIPB_ECOHS ;
DR   A1A8Q5, LIPB_ECOK1 ;  Q0TK43, LIPB_ECOL5 ;  P60722, LIPB_ECOL6 ;
DR   B1IYH8, LIPB_ECOLC ;  P60720, LIPB_ECOLI ;  B7N9N6, LIPB_ECOLU ;
DR   B6I139, LIPB_ECOSE ;  B1LKM1, LIPB_ECOSM ;  Q1RET2, LIPB_ECOUT ;
DR   Q3YRI1, LIPB_EHRCJ ;  Q2GH92, LIPB_EHRCR ;  Q5FFZ7, LIPB_EHRRG ;
DR   Q5HAP4, LIPB_EHRRW ;  A4W816, LIPB_ENT38 ;  Q6D7M7, LIPB_ERWCT ;
DR   B2VBK0, LIPB_ERWT9 ;  Q2NDR7, LIPB_ERYLH ;  A5FIL6, LIPB_FLAJ1 ;
DR   A6GYW1, LIPB_FLAPJ ;  Q2JB35, LIPB_FRASC ;  Q14HH8, LIPB_FRAT1 ;
DR   A7NC90, LIPB_FRATF ;  Q2A3E7, LIPB_FRATH ;  B2SGJ2, LIPB_FRATM ;
DR   A0Q6D2, LIPB_FRATN ;  Q0BLW1, LIPB_FRATO ;  Q5NG26, LIPB_FRATT ;
DR   A4IXX8, LIPB_FRATW ;  B5EDZ5, LIPB_GEOBB ;  Q39S09, LIPB_GEOMG ;
DR   Q74AE2, LIPB_GEOSL ;  C6E0V3, LIPB_GEOSM ;  A5GAC4, LIPB_GEOUR ;
DR   Q7ND22, LIPB_GLOVI ;  A9HJ12, LIPB_GLUDA ;  Q5FUX5, LIPB_GLUOX ;
DR   A0M5H7, LIPB_GRAFK ;  Q7VKB0, LIPB_HAEDU ;  Q4QPL7, LIPB_HAEI8 ;
DR   A5UBB1, LIPB_HAEIE ;  A5UFJ9, LIPB_HAEIG ;  P44464, LIPB_HAEIN ;
DR   Q0I1H7, LIPB_HAES1 ;  B0UVP8, LIPB_HAES2 ;  Q2SA37, LIPB_HAHCH ;
DR   A1WVS9, LIPB_HALHL ;  A4G9C5, LIPB_HERAR ;  Q0C3A9, LIPB_HYPNA ;
DR   Q5QYE6, LIPB_IDILO ;  A6T344, LIPB_JANMA ;  Q28SZ3, LIPB_JANSC ;
DR   B5XZS4, LIPB_KLEP3 ;  A6T691, LIPB_KLEP7 ;  O13476, LIPB_KLULA ;
DR   B2GJ87, LIPB_KOCRD ;  C1D5T4, LIPB_LARHH ;  Q5X551, LIPB_LEGPA ;
DR   A5IC06, LIPB_LEGPC ;  Q5ZVC9, LIPB_LEGPH ;  Q5WWD9, LIPB_LEGPL ;
DR   Q6AFG6, LIPB_LEIXX ;  Q04TD5, LIPB_LEPBJ ;  Q052G1, LIPB_LEPBL ;
DR   Q72QP1, LIPB_LEPIC ;  Q8F5F1, LIPB_LEPIN ;  Q2W9F0, LIPB_MAGSA ;
DR   A0L510, LIPB_MAGSM ;  Q65RH6, LIPB_MANSM ;  A1U3B4, LIPB_MARAV ;
DR   Q0ANV0, LIPB_MARMM ;  A6VZ75, LIPB_MARMS ;  Q11JI3, LIPB_MESSB ;
DR   Q60CJ7, LIPB_METCA ;  Q1GYC2, LIPB_METFK ;  A2SCI8, LIPB_METPP ;
DR   A0QEY7, LIPB_MYCA1 ;  Q7VEN4, LIPB_MYCBO ;  A1KKQ9, LIPB_MYCBP ;
DR   C1AQD2, LIPB_MYCBT ;  A4TBJ9, LIPB_MYCGI ;  B8ZQK0, LIPB_MYCLB ;
DR   O32961, LIPB_MYCLE ;  B2HHL3, LIPB_MYCMM ;  Q73YJ7, LIPB_MYCPA ;
DR   A0R074, LIPB_MYCS2 ;  A3Q1S7, LIPB_MYCSJ ;  A1UIB3, LIPB_MYCSK ;
DR   Q1B6R2, LIPB_MYCSS ;  A5U4P5, LIPB_MYCTA ;  Q10404, LIPB_MYCTU ;
DR   A0PNH8, LIPB_MYCUA ;  A1TB25, LIPB_MYCVP ;  Q9X6X4, LIPB_MYXXA ;
DR   Q5F8I1, LIPB_NEIG1 ;  B4RLL0, LIPB_NEIG2 ;  A9LZ96, LIPB_NEIM0 ;
DR   Q9JUC7, LIPB_NEIMA ;  Q9JZA4, LIPB_NEIMB ;  A1KU21, LIPB_NEIMF ;
DR   Q2GEU6, LIPB_NEOSM ;  Q0AI04, LIPB_NITEC ;  Q82UJ6, LIPB_NITEU ;
DR   Q1QLD9, LIPB_NITHX ;  Q2Y7I8, LIPB_NITMU ;  Q3J7W3, LIPB_NITOC ;
DR   Q3SRU9, LIPB_NITWN ;  Q5YZ58, LIPB_NOCFA ;  B2IVM2, LIPB_NOSP7 ;
DR   Q8YSA4, LIPB_NOSS1 ;  Q2GC80, LIPB_NOVAD ;  B6JF54, LIPB_OLICO ;
DR   A5CEL3, LIPB_ORITB ;  B3CRE6, LIPB_ORITI ;  A6L9E1, LIPB_PARD8 ;
DR   A1B3D5, LIPB_PARDP ;  A7HWU9, LIPB_PARL1 ;  Q00520, LIPB_PARVE ;
DR   P57977, LIPB_PASMU ;  C6DBV7, LIPB_PECCP ;  Q3A7N4, LIPB_PELCD ;
DR   A1AMT7, LIPB_PELPD ;  Q4FLP4, LIPB_PELUB ;  C0QQ61, LIPB_PERMH ;
DR   Q7N766, LIPB_PHOLL ;  Q6LN88, LIPB_PHOPR ;  A1VIU0, LIPB_POLNA ;
DR   B1XSA5, LIPB_POLNS ;  Q12GR3, LIPB_POLSJ ;  A4T0B0, LIPB_POLSQ ;
DR   Q7MUY1, LIPB_PORGI ;  Q6A9W7, LIPB_PROAC ;  Q51854, LIPB_PROHO ;
DR   A3PBB9, LIPB_PROM0 ;  A2C0K7, LIPB_PROM1 ;  A8G3B3, LIPB_PROM2 ;
DR   A9BE20, LIPB_PROM4 ;  A2BV61, LIPB_PROM5 ;  Q31CD7, LIPB_PROM9 ;
DR   Q7VDH8, LIPB_PROMA ;  Q7V8V9, LIPB_PROMM ;  Q7V2R8, LIPB_PROMP ;
DR   A2BPM9, LIPB_PROMS ;  Q46H10, LIPB_PROMT ;  Q48DM5, LIPB_PSE14 ;
DR   Q15VL2, LIPB_PSEA6 ;  A6V0B3, LIPB_PSEA7 ;  B7V8B6, LIPB_PSEA8 ;
DR   Q02SG4, LIPB_PSEAB ;  Q9X6V9, LIPB_PSEAE ;  Q1I4G0, LIPB_PSEE4 ;
DR   Q4K5G9, LIPB_PSEF5 ;  C3K2L9, LIPB_PSEFS ;  Q3IJ80, LIPB_PSEHT ;
DR   A4XYX4, LIPB_PSEMY ;  A5W9I6, LIPB_PSEP1 ;  Q3K6A3, LIPB_PSEPF ;
DR   B0KJX5, LIPB_PSEPG ;  Q88DM4, LIPB_PSEPK ;  B1J143, LIPB_PSEPW ;
DR   Q87VW6, LIPB_PSESM ;  Q4ZN83, LIPB_PSEU2 ;  A4VQZ7, LIPB_PSEU5 ;
DR   Q4FS63, LIPB_PSYA2 ;  Q1QBT8, LIPB_PSYCK ;  A1SZ16, LIPB_PSYIN ;
DR   Q8ZUR4, LIPB_PYRAE ;  A4WK37, LIPB_PYRAR ;  A3MW04, LIPB_PYRCJ ;
DR   B2UE02, LIPB_RALPJ ;  Q8Y2L2, LIPB_RALSO ;  A9WS39, LIPB_RENSM ;
DR   B3PP01, LIPB_RHIE6 ;  Q2K833, LIPB_RHIEC ;  Q1MG80, LIPB_RHIL3 ;
DR   Q98KT0, LIPB_RHILO ;  Q92QD5, LIPB_RHIME ;  Q21RG9, LIPB_RHOFD ;
DR   C1AUB9, LIPB_RHOOB ;  Q2IXI4, LIPB_RHOP2 ;  Q07L16, LIPB_RHOP5 ;
DR   Q6N514, LIPB_RHOPA ;  Q211P6, LIPB_RHOPB ;  Q135D0, LIPB_RHOPS ;
DR   B3QAV6, LIPB_RHOPT ;  Q2RSU9, LIPB_RHORT ;  A3PH28, LIPB_RHOS1 ;
DR   Q3J5A6, LIPB_RHOS4 ;  A4WQA7, LIPB_RHOS5 ;  Q0SHK6, LIPB_RHOSR ;
DR   C3PM18, LIPB_RICAE ;  A8GQA5, LIPB_RICAH ;  A8GUN4, LIPB_RICB8 ;
DR   Q1RKI1, LIPB_RICBR ;  A8F0A0, LIPB_RICCK ;  Q92FX0, LIPB_RICCN ;
DR   Q4UJQ5, LIPB_RICFE ;  A8F300, LIPB_RICM5 ;  Q9ZC91, LIPB_RICPR ;
DR   C4K2Y1, LIPB_RICPU ;  B0BVP3, LIPB_RICRO ;  A8GU54, LIPB_RICRS ;
DR   Q68VN7, LIPB_RICTY ;  A5US49, LIPB_ROSS1 ;  Q1AT14, LIPB_RUBXD ;
DR   A1AWI7, LIPB_RUTMC ;  Q21FD9, LIPB_SACD2 ;  A8LYF4, LIPB_SALAI ;
DR   Q57RU1, LIPB_SALCH ;  Q5PM99, LIPB_SALPA ;  Q2RZI1, LIPB_SALRD ;
DR   Q8Z8I2, LIPB_SALTI ;  A4XA20, LIPB_SALTO ;  Q8ZR03, LIPB_SALTY ;
DR   O36017, LIPB_SCHPO ;  A8GB10, LIPB_SERP5 ;  A1S8U0, LIPB_SHEAM ;
DR   B8E4W5, LIPB_SHEB2 ;  A3D7P8, LIPB_SHEB5 ;  A6WRL1, LIPB_SHEB8 ;
DR   A9L013, LIPB_SHEB9 ;  Q12QX0, LIPB_SHEDO ;  Q087L4, LIPB_SHEFN ;
DR   B0TR56, LIPB_SHEHH ;  A3QH59, LIPB_SHELP ;  Q8EHQ5, LIPB_SHEON ;
DR   A8H7D4, LIPB_SHEPA ;  A4Y9G1, LIPB_SHEPC ;  B8CSH6, LIPB_SHEPW ;
DR   A0KTV5, LIPB_SHESA ;  A8FZ22, LIPB_SHESH ;  Q0HLK2, LIPB_SHESM ;
DR   Q0HXV6, LIPB_SHESR ;  A1RGT3, LIPB_SHESW ;  B1KDX2, LIPB_SHEWM ;
DR   B2TU88, LIPB_SHIB3 ;  Q324R3, LIPB_SHIBS ;  Q32IV0, LIPB_SHIDS ;
DR   Q0T6P0, LIPB_SHIF8 ;  Q7UDD0, LIPB_SHIFL ;  Q3Z4G2, LIPB_SHISS ;
DR   Q5LTM4, LIPB_SILPO ;  A6U899, LIPB_SINMW ;  Q2NUV7, LIPB_SODGM ;
DR   Q02AK4, LIPB_SOLUE ;  Q1GTF8, LIPB_SPHAL ;  A5V649, LIPB_SPHWW ;
DR   Q82AP6, LIPB_STRAW ;  Q8CK04, LIPB_STRCO ;  B1VZM4, LIPB_STRGG ;
DR   Q31KN6, LIPB_SYNE7 ;  A0LIW0, LIPB_SYNFM ;  Q2JTV2, LIPB_SYNJA ;
DR   Q2JKB7, LIPB_SYNJB ;  Q5N180, LIPB_SYNP6 ;  A5GJ90, LIPB_SYNPW ;
DR   Q7U8F2, LIPB_SYNPX ;  Q3AZ50, LIPB_SYNS9 ;  Q3AI29, LIPB_SYNSC ;
DR   P74519, LIPB_SYNY3 ;  Q8DKM7, LIPB_THEEB ;  Q47R87, LIPB_THEFY ;
DR   B0K8D0, LIPB_THEP3 ;  B0K3J8, LIPB_THEPX ;  Q72GV2, LIPB_THET2 ;
DR   Q5SLQ3, LIPB_THET8 ;  Q8R9E0, LIPB_THETN ;  Q31F43, LIPB_THICR ;
DR   Q3SM28, LIPB_THIDA ;  Q10ZL5, LIPB_TRIEI ;  Q83I07, LIPB_TROW8 ;
DR   Q83G63, LIPB_TROWT ;  C5CP20, LIPB_VARPS ;  A1WF49, LIPB_VEREI ;
DR   A5CWR5, LIPB_VESOH ;  A5F2Y1, LIPB_VIBC3 ;  Q9KTF8, LIPB_VIBCH ;
DR   Q5E6V8, LIPB_VIBF1 ;  A7MY97, LIPB_VIBHB ;  Q87RR0, LIPB_VIBPA ;
DR   B7VKE7, LIPB_VIBSL ;  Q8DFD2, LIPB_VIBVU ;  Q7MN16, LIPB_VIBVY ;
DR   Q8D326, LIPB_WIGBR ;  Q73GE2, LIPB_WOLPM ;  B3CLJ0, LIPB_WOLPP ;
DR   Q5GT50, LIPB_WOLTR ;  Q8PPL9, LIPB_XANAC ;  Q3BXQ4, LIPB_XANC5 ;
DR   Q4UYT3, LIPB_XANC8 ;  B0RNP8, LIPB_XANCB ;  Q8P589, LIPB_XANCP ;
DR   Q2NYZ1, LIPB_XANOM ;  Q5GVR6, LIPB_XANOR ;  Q9PDV9, LIPB_XYLFA ;
DR   Q87DZ8, LIPB_XYLFT ;  Q06005, LIPB_YEAST ;  A1JPR8, LIPB_YERE8 ;
DR   A7FKY8, LIPB_YERP3 ;  Q1C508, LIPB_YERPA ;  B2K875, LIPB_YERPB ;
DR   Q8ZDG9, LIPB_YERPE ;  Q1CKR5, LIPB_YERPN ;  A4TP08, LIPB_YERPP ;
DR   Q66DF4, LIPB_YERPS ;  B1JGB6, LIPB_YERPY ;  Q5NMY4, LIPB_ZYMMO ;
DR   B7GHD6, LIPM_ANOFW ;  A7Z6M0, LIPM_BACA2 ;  Q81M24, LIPM_BACAN ;
DR   Q818P0, LIPM_BACCR ;  Q9K938, LIPM_BACHD ;  P54511, LIPM_BACSU ;
DR   D5WQ56, LIPM_BACT2 ;  C0ZBW9, LIPM_BREBN ;  Q3AET1, LIPM_CARHZ ;
DR   Q189T1, LIPM_CLOD6 ;  B1YLP0, LIPM_EXIS2 ;  C4KZ18, LIPM_EXISA ;
DR   Q5KX81, LIPM_GEOKA ;  B1HS22, LIPM_LYSSC ;  B9E6R6, LIPM_MACCJ ;
DR   Q2RH52, LIPM_MOOTA ;  Q8ERL9, LIPM_OCEIH ;  Q2FY37, LIPM_STAA8 ;
DR   Q5HP16, LIPM_STAEQ ;  Q67N40, LIPM_SYMTH ;  Q29R99, LIPT2_DANRE;
DR   Q9VN27, LIPT2_DROME;  A6NK58, LIPT2_HUMAN;  Q9D009, LIPT2_MOUSE;
DR   Q0VFH3, LIPT2_XENTR;
//
ID   2.3.1.182
DE   (R)-citramalate synthase.
CA   Acetyl-CoA + pyruvate + H(2)O = CoA + (2R)-2-hydroxy-2-
CA   methylbutanedioate.
CC   -!- Involved in a novel pyruvate pathway for isoleucine biosynthesis that
CC       is found mainly in archaea.
CC   -!- Can be inhibited by isoleucine, the end-product of the pathway,
CC       but not by leucine.
CC   -!- Highly specific for pyruvate as substrate, as the 2-oxo acids
CC       3-methyl-2-oxobutanoate, 2-oxobutanoate, 4-methyl-2-oxopentanoate,
CC       2-oxohexanoate and 2-oxoglutarate cannot act as substrate.
DR   O29305, CIMA_ARCFU ;  Q8TJJ1, CIMA_METAC ;  Q58787, CIMA_METJA ;
DR   Q8TYM1, CIMA_METKA ;  P58966, CIMA_METMA ;  A3CUF2, CIMA_METMJ ;
DR   B8GEI1, CIMA_METPE ;  O26819, CIMA_METTH ;
//
ID   2.3.1.183
DE   Phosphinothricin acetyltransferase.
AN   PPT acetyltransferase.
AN   PPT N-acetyltransferase.
CA   Acetyl-CoA + phosphinothricin = CoA + N-acetylphosphinothricin.
CC   -!- The substrate phosphinothricin is used as a nonselective herbicide
CC       and is a potent inhibitor of EC 6.3.1.2, a key enzyme of nitrogen
CC       metabolism in plants.
PR   PROSITE; PDOC51186;
DR   P31668, PAT_ALCFA  ;  P21861, PAT_STRCO  ;  P16426, PAT_STRHY  ;
DR   Q57146, PAT_STRVR  ;  P71043, YWNH_BACSU ;
//
ID   2.3.1.184
DE   Acyl-homoserine-lactone synthase.
AN   Acyl homoserine lactone synthase.
AN   Acyl-homoserine lactone synthase.
AN   Acyl-homoserinelactone synthase.
AN   Acylhomoserine lactone synthase.
AN   AHL synthase.
AN   AHSL synthase.
AN   Autoinducer synthase.
AN   Autoinducer synthesis protein.
AN   N-acyl homoserine lactone synthase.
CA   An acyl-[acyl-carrier-protein] + S-adenosyl-L-methionine = [acyl-carrier-
CA   protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone.
CC   -!- Acyl-homoserine lactones (AHLs) are produced by a number of bacterial
CC       species and are used by them to regulate the expression of virulence
CC       genes in a process known as quorum-sensing.
CC   -!- Each bacterial cell has a basal level of AHL and, once the population
CC       density reaches a critical level, it triggers AHL-signaling which,
CC       in turn, initiates the expression of particular virulence genes.
CC   -!- N-(3-oxohexanoyl)-[acyl-carrier-protein] and hexanoyl-[acyl-carrier-
CC       protein] are the best substrates.
CC   -!- The fatty-acyl substrate is derived from fatty-acid biosynthesis
CC       through acyl-[acyl-carrier-protein] rather than from fatty-acid
CC       degradation through acyl-CoA.
CC   -!- S-adenosyl-L-methionine cannot be replaced by methionine,
CC       S-adenosylhomocysteine, homoserine or homoserine lactone.
PR   PROSITE; PDOC51186;
DR   Q44058, AHYI_AERHY ;  P70774, ASAI_AERSA ;  P33880, CARI_PECCC ;
DR   P33881, EAGI_ENTAG ;  Q46968, ECHI_ERWCH ;  P54656, ESAI_ERWST ;
DR   Q47187, EXPI_DICD3 ;  P33882, EXPI_PECCC ;  P33883, LASI_PSEAE ;
DR   P12747, LUXI_VIBFI ;  P35328, LUXJ_VIBF1 ;  P54298, LUXM_VIBHA ;
DR   A7MRY3, LUXM_VIBHB ;  B7VQM9, LUXM_VIBSL ;  Q87NA8, OPAM_VIBPA ;
DR   Q51522, PHZI_PSECL ;  Q51785, PHZI_PSEFL ;  P52990, PSYI_PSESZ ;
DR   O54451, RAII_RHIET ;  P54291, RHLI_PSEAE ;  P58584, SOLI1_RALSO;
DR   O30920, SOLI2_RALSO;  P52989, SWRI_SERLI ;  P33907, TRAI_AGRT5 ;
DR   P33904, TRAI_RHIRD ;  P55394, TRAI_RHISN ;  P74945, VANI_VIBAN ;
DR   Q9FDA3, VANM_VIBAN ;  P52988, YENI_YEREN ;  O87970, YUKI_YERRU ;
//
ID   2.3.1.185
DE   Tropine acyltransferase.
AN   TAT.
AN   Tropine acetyltransferase.
AN   Tropine tigloyltransferase.
CA   An acyl-CoA + tropine = CoA + an O-acyltropine.
CC   -!- Exhibits absolute specificity for the endo/3-alpha configuration
CC       found in tropine as pseudotropine (tropan-3-beta-ol; see
CC       EC 2.3.1.186) is not a substrate.
CC   -!- Acts on a wide range of aliphatic acyl-CoA derivatives, with tigloyl-
CC       CoA and acetyl-CoA being the best substrates.
CC   -!- It is probably involved in the formation of the tropane alkaloid
CC       littorine, which is a precursor of hyoscyamine.
//
ID   2.3.1.186
DE   Pseudotropine acyltransferase.
AN   PAT.
AN   Pseudotropine acetyltransferase.
AN   Pseudotropine tigloyltransferase.
CA   An acyl-CoA + pseudotropine = CoA + an O-acylpseudotropine.
CC   -!- Exhibits absolute specificity for the exo/3-beta configuration found
CC       in pseudotropine as tropine (tropan-3-alpha-ol; see EC 2.3.1.185) and
CC       nortropine are not substrates.
CC   -!- Acts on a wide range of aliphatic acyl-CoA derivatives, including
CC       acetyl-CoA, beta-methylcrotonyl-CoA and tigloyl-CoA.
//
ID   2.3.1.187
DE   Acetyl-S-ACP:malonate ACP transferase.
AN   ACP transferase.
AN   Malonate/acetyl-CoA transferase.
CA   An acetyl-[acyl-carrier protein] + malonate = a malonyl-[acyl-carrier
CA   protein] + acetate.
CC   -!- This is the first step in the catalysis of malonate decarboxylation
CC       and involves the exchange of an acetyl thioester residue bound to the
CC       activated acyl-carrier protein (ACP) subunit of the malonate
CC       decarboxylase complex for a malonyl thioester residue.
CC   -!- This enzyme forms the alpha subunit of the multienzyme complexes
CC       EC 4.1.1.88 and EC 4.1.1.89.
CC   -!- Can also use acetyl-CoA as a substrate but more slowly.
//
ID   2.3.1.188
DE   Omega-hydroxypalmitate O-feruloyl transferase.
AN   HHT.
AN   Hydroxycinnamoyl-CoA omega-hydroxypalmitic acid
AN   O-hydroxycinnamoyltransferase.
CA   Feruloyl-CoA + 16-hydroxypalmitate = CoA + 16-feruloyloxypalmitate.
CC   -!- p-coumaroyl-CoA and sinapoyl-CoA also act as substrates.
CC   -!- The enzyme is widely distributed in roots of higher plants.
DR   Q94CD1, HHT1_ARATH ;
//
ID   2.3.1.189
DE   Mycothiol synthase.
CA   Desacetylmycothiol + acetyl-CoA = mycothiol + coenzyme-A.
CC   -!- This enzyme catalyzes the last step in the biosynthesis of mycothiol,
CC       the major thiol in most actinomycetes, including Mycobacterium.
CC   -!- The enzyme is a member of a large family of GCN5-related
CC       N-acetyltransferases (GNATs).
CC   -!- The enzyme has been purified from Mycobacterium tuberculosis H37Rv.
CC   -!- Acetyl-CoA is the preferred CoA thioester but propionyl-CoA is also a
CC       substrate.
PR   PROSITE; PDOC51186;
DR   A0LWI8, MSHD_ACIC1 ;  C7M077, MSHD_ACIFD ;  C6WPR7, MSHD_ACTMD ;
DR   Q5EDG0, MSHD_AMYMD ;  A1R8Y2, MSHD_ARTAT ;  B8HD44, MSHD_ARTCA ;
DR   A0JZC2, MSHD_ARTS2 ;  C5C246, MSHD_BEUC1 ;  C7MGB3, MSHD_BRAFD ;
DR   C7QKH8, MSHD_CATAD ;  D5UJR1, MSHD_CELFN ;  A5CTZ8, MSHD_CLAM3 ;
DR   B0RAV5, MSHD_CLAMS ;  C3PIU4, MSHD_CORA7 ;  Q6NFH9, MSHD_CORDI ;
DR   Q8FMN5, MSHD_COREF ;  A4QGX4, MSHD_CORGB ;  Q8NMJ7, MSHD_CORGL ;
DR   Q4JXC9, MSHD_CORJK ;  C4LH71, MSHD_CORK4 ;  B1VII5, MSHD_CORU7 ;
DR   Q0RS64, MSHD_FRAAA ;  Q2JFW4, MSHD_FRASC ;  A8LDL3, MSHD_FRASN ;
DR   D2S4P5, MSHD_GEOOG ;  D0L3V5, MSHD_GORB4 ;  C7R1N6, MSHD_JONDD ;
DR   A6W6C7, MSHD_KINRD ;  B2GI63, MSHD_KOCRD ;  D2Q187, MSHD_KRIFD ;
DR   C7NK43, MSHD_KYTSD ;  C5CC88, MSHD_MICLC ;  A0QAU8, MSHD_MYCA1 ;
DR   B1MI19, MSHD_MYCA9 ;  Q7U173, MSHD_MYCBO ;  A1KGV2, MSHD_MYCBP ;
DR   C1ALF4, MSHD_MYCBT ;  A4T7H0, MSHD_MYCGI ;  B8ZSU0, MSHD_MYCLB ;
DR   Q9CBC9, MSHD_MYCLE ;  B2HH13, MSHD_MYCMM ;  Q743D5, MSHD_MYCPA ;
DR   A4ZHT6, MSHD_MYCS2 ;  A3Q695, MSHD_MYCSJ ;  A1ULU4, MSHD_MYCSK ;
DR   Q1B3A6, MSHD_MYCSS ;  A5U0K8, MSHD_MYCTA ;  A5WKI8, MSHD_MYCTF ;
DR   C6DVC4, MSHD_MYCTK ;  O53831, MSHD_MYCTU ;  A0PLC7, MSHD_MYCUA ;
DR   A1TFB7, MSHD_MYCVP ;  C8XA55, MSHD_NAKMY ;  D7AWZ7, MSHD_NOCDD ;
DR   Q5Z297, MSHD_NOCFA ;  A1SPL0, MSHD_NOCSJ ;  D7GG24, MSHD_PROFC ;
DR   A9WNI5, MSHD_RENSM ;  C0ZP17, MSHD_RHOE4 ;  C1ATC6, MSHD_RHOOB ;
DR   Q0S740, MSHD_RHOSR ;  D2NRH2, MSHD_ROTMD ;  A4FQD4, MSHD_SACEN ;
DR   C7MRC4, MSHD_SACVD ;  A8LYQ4, MSHD_SALAI ;  A4X1M6, MSHD_SALTO ;
DR   D1BE23, MSHD_SANKS ;  D6ZEJ5, MSHD_SEGRD ;  D3Q4A8, MSHD_STANL ;
DR   Q82G40, MSHD_STRAW ;  D7C376, MSHD_STRBB ;  Q9KZV0, MSHD_STRCO ;
DR   B1VS15, MSHD_STRGG ;  D2B7W7, MSHD_STRRD ;  C9ZFL1, MSHD_STRSW ;
DR   D6Y4C5, MSHD_THEBD ;  D1A4F4, MSHD_THECD ;  Q47LA0, MSHD_THEFY ;
DR   D5UXA4, MSHD_TSUPD ;  D1BV84, MSHD_XYLCX ;
//
ID   2.3.1.190
DE   Acetoin dehydrogenase.
CA   Acetoin + coenzyme A + NAD(+) = acetaldehyde + acetyl-CoA + NADH.
CF   Thiamine phosphate.
CC   -!- This enzyme, which belongs to the family of 2-oxo acid dehydrogenase
CC       complexes, catalyzes the oxidative-hydrolytic cleavage of acetoin to
CC       acetaldehyde and acetyl-CoA in many bacterial strains, both aerobic
CC       and anaerobic.
CC   -!- The enzyme is composed of multiple copies of three enzymatic
CC       components:acetoin oxidoreductase (E1), dihydrolipoamide
CC       acetyltransferase (E2) and dihydrolipoyl dehydrogenase (E3).
PR   PROSITE; PDOC00073;
//
ID   2.3.1.191
DE   UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase.
AN   UDP-3-O-(3-hydroxymyristoyl)-D-glucosamine N-acyltransferase.
AN   UDP-3-O-acyl-glucosamine N-acyltransferase.
CA   (3R)-3-hydroxymyristoyl-[acyl-carrier-protein] + UDP-3-O-((3R)-
CA   hydroxymyristoyl)-alpha-D-glucosamine = UDP-2,3-bis(O-(3R)-3-
CA   hydroxymyristoyl)-alpha-D-glucosamine + a holo-[acyl-carrier-protein].
CC   -!- The enzyme catalyzes a step of lipid A biosynthesis.
CC   -!- LpxD from Escherichia coli prefers (R,S)-3-hydroxymyristoyl-[acyl-
CC       carrier protein] over (R,S)-3-hydroxypalmitoyl-[acyl-carrier
CC       protein].
CC   -!- E.coli lipid A acyltransferases do not have an absolute specificity
CC       for 14-carbon hydroxy fatty acids but can transfer fatty acids
CC       differing by one carbon unit if the fatty acid substrates are
CC       available.
CC   -!- When grown on 1% propionic acid, lipid A also contains the odd-chain
CC       fatty acids tridecanoic acid, pentadecanoic acid, hydroxytridecanoic
CC       acid, and hydroxypentadecanoic acid.
CC   -!- Formerly EC 2.3.1.n1.
//
ID   2.3.1.192
DE   Glycine N-phenylacetyltransferase.
AN   Arylacetyl-CoA N-acyltransferase.
AN   Arylacetyltransferase.
CA   Phenylacetyl-CoA + glycine = phenylacetylglycine + CoA.
CC   -!- Not identical with EC 2.3.1.13.
CC   -!- This enzyme was purified from bovine liver mitochondria.
CC   -!- L-asparagine, L-glutamine and L-arginine are alternative substrates
CC       to glycine, but have higher Km values.
DR   O77512, GLYAL_BOVIN;
//
ID   2.3.1.193
DE   tRNA(Met) cytidine acetyltransferase.
CA   (Elongator tRNA(Met))-cytidine(34) + ATP + acetyl-CoA = (elongator
CA   tRNA(Met))-N(4)-acetylcytidine(34) + ADP + phosphate + CoA.
CC   -!- The enzyme acetylates the wobble base C34 of the CAU anticodon of
CC       elongation-specific tRNA(Met).
CC   -!- Escherichia coli TmcA strictly discriminates elongator tRNA(Met) from
CC       tRNA(Ile), which is structurally similar and has the same anticodon
CC       loop, mainly by recognizing the C27-G43 pair in the anticodon stem.
CC   -!- The enzyme can use GTP in place of ATP for formation of N(4)-
CC       acetylcytidine.
DR   A3N059, TMCA_ACTP2 ;  Q9YBQ6, TMCA_AERPE ;  A8ADB3, TMCA_CITK8 ;
DR   P76562, TMCA_ECOLI ;  Q6D7Q9, TMCA_ERWCT ;  Q7VLN6, TMCA_HAEDU ;
DR   P44140, TMCA_HAEIN ;  Q5V5M5, TMCA_HALMA ;  Q5QY69, TMCA_IDILO ;
DR   Q8TYZ5, TMCA_METKA ;  D5C1K8, TMCA_NITHN ;  C7BGY4, TMCA_PHOAA ;
DR   Q9UZ78, TMCA_PYRAB ;  Q8ZN74, TMCA_SALTY ;  Q0T243, TMCA_SHIF8 ;
DR   C3N792, TMCA_SULIY ;  A1RY08, TMCA_THEPD ;  Q9KKJ5, TMCA_VIBCH ;
DR   A1JL12, TMCA_YERE8 ;  D0JFM7, TMCA_YERPD ;
//
ID   2.3.1.194
DE   Acetoacetyl-CoA synthase.
AN   NphT7.
CA   Acetyl-CoA + malonyl-CoA = acetoacetyl-CoA + CoA + CO(2).
CC   -!- The enzyme from the soil bacterium Streptomyces sp. CL190 produces
CC       acetoacetyl-CoA to be used for mevalonate production via the
CC       mevalonate pathway.
CC   -!- Unlike the homologous EC 2.3.1.180 this enzyme does not accept
CC       malonyl-[acyl-carrier-protein] as a substrate.
//
ID   2.3.1.195
DE   (Z)-3-hexen-1-ol acetyltransferase.
CA   Acetyl-CoA + (3Z)-hex-3-en-ol = (3Z)-hex-3-en-1-yl acetate + CoA.
CC   -!- The enzyme is resonsible for the production of (3Z)-hex-3-en-1-yl
CC       acetate, the major volatile compound released upon mechanical
CC       wounding of the leaves of Arabidopsis thaliana.
DR   Q9SRQ2, CHAT_ARATH ;
//
ID   2.3.1.196
DE   Benzyl alcohol O-benzoyltransferase.
CA   Benzoyl-CoA + benzyl alcohol = benzyl benzoate + CoA.
CC   -!- The enzyme is involved in volatile benzenoid and benzoic acid
CC       biosynthesis.
CC   -!- The enzyme from Petunia hybrida also catalyzes the formation of
CC       2-phenylethyl benzoate from benzoyl-CoA and 2-phenylethanol.
CC   -!- The apparent catalytic efficiency of the enzyme from Petunia hybrida
CC       with benzoyl-CoA is almost 6-fold higher than with acetyl-CoA.
DR   Q8GT21, BEBT_CLABR ;  Q8GT20, BEBT_TOBAC ;
//
ID   2.3.1.n1
DE   Transferred entry: 2.3.1.191.
//
ID   2.3.2.1
DE   D-glutamyltransferase.
AN   D-glutamyl transpeptidase.
CA   L(or D)-glutamine + D-glutamyl-peptide = NH(3) + 5-glutamyl-D-glutamyl-
CA   peptide.
//
ID   2.3.2.2
DE   Gamma-glutamyltransferase.
AN   Gamma-glutamyl transpeptidase.
AN   Glutamyl transpeptidase.
CA   (1) (5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl amino
CA   acid.
CA   (2) Glutathione + H(2)O = L-cysteinylglycine + L-glutamate.
PR   PROSITE; PDOC00404;
DR   Q05902, ECM38_YEAST;  P19440, GGT1_HUMAN ;  Q60928, GGT1_MOUSE ;
DR   P20735, GGT1_PIG   ;  P07314, GGT1_RAT   ;  Q9US04, GGT1_SCHPO ;
DR   P36268, GGT2_HUMAN ;  O14194, GGT2_SCHPO ;  A6NGU5, GGT3_HUMAN ;
DR   P36269, GGT5_HUMAN ;  Q9Z2A9, GGT5_MOUSE ;  Q9QWE9, GGT5_RAT   ;
DR   A7YWM1, GGT6_BOVIN ;  Q6P531, GGT6_HUMAN ;  Q6PDE7, GGT6_MOUSE ;
DR   Q6IE08, GGT6_RAT   ;  Q0V8L2, GGT7_BOVIN ;  Q9UJ14, GGT7_HUMAN ;
DR   Q99JP7, GGT7_MOUSE ;  Q99MZ4, GGT7_RAT   ;  P63186, GGT_BACNA  ;
DR   P54422, GGT_BACSU  ;  P18956, GGT_ECOLI  ;  Q9I406, GGT_PSEAE  ;
DR   P36267, GGT_PSEUA  ;  P74181, GGT_SYNY3  ;  P15557, PAC1_PSES3 ;
DR   Q05053, PAC1_PSESV ;  O05218, YWRD_BACSU ;
//
ID   2.3.2.3
DE   Lysyltransferase.
CA   L-lysyl-tRNA + phosphatidylglycerol = tRNA + 3-phosphatidyl-1'-(3'-O-
CA   L-lysyl)glycerol.
DR   D0LB45, LYSX_GORB4 ;  A0QHC4, LYSX_MYCA1 ;  B1MAX9, LYSX_MYCA9 ;
DR   Q7VEV7, LYSX_MYCBO ;  A1KJ57, LYSX_MYCBP ;  C1ANR3, LYSX_MYCBT ;
DR   A4T9U2, LYSX_MYCGI ;  B8ZRJ4, LYSX_MYCLB ;  Q9CC23, LYSX_MYCLE ;
DR   B2HR11, LYSX_MYCMM ;  Q740J9, LYSX_MYCPA ;  A0QYV1, LYSX_MYCS2 ;
DR   A3Q0V0, LYSX_MYCSJ ;  A1UHB3, LYSX_MYCSK ;  Q1B7P4, LYSX_MYCSS ;
DR   A5U2Z7, LYSX_MYCTA ;  A5WMW1, LYSX_MYCTF ;  C6DS31, LYSX_MYCTK ;
DR   P94974, LYSX_MYCTU ;  A0PP57, LYSX_MYCUA ;  A1TAC7, LYSX_MYCVP ;
DR   Q5Z3P6, LYSX_NOCFA ;  C0ZL89, LYSX_RHOE4 ;  C1B7Z5, LYSX_RHOOB ;
DR   Q0SAA3, LYSX_RHOSR ;  C0H3X7, MPRF_BACSU ;  Q2G2M2, MPRF_STAA8 ;
DR   Q5HG59, MPRF_STAAC ;  Q99UB9, MPRF_STAAM ;  Q7A5R9, MPRF_STAAN ;
DR   Q6GH45, MPRF_STAAR ;  Q6G9J9, MPRF_STAAS ;  Q9AIV3, MPRF_STAAU ;
DR   Q8NWU7, MPRF_STAAW ;  Q5HPI1, MPRF_STAEQ ;  Q8CPC0, MPRF_STAES ;
DR   Q4L667, MPRF_STAHJ ;  Q93QY7, MPRF_STAXY ;
//
ID   2.3.2.4
DE   Gamma-glutamylcyclotransferase.
CA   (Gamma-L-glutamyl)-L-amino acid = 5-oxoproline + L-amino acid.
CC   -!- Acts on derivatives of L-glutamate, L-2-aminobutanoate, L-alanine and
CC       glycine.
DR   Q0VFX9, A2LD1_BOVIN;  Q9BVM4, A2LD1_HUMAN;  Q923B0, A2LD1_MOUSE;
DR   Q4KM86, A2LD1_RAT  ;  Q66KX0, A2LD1_XENLA;  Q66I06, A2LDA_DANRE;
DR   A3KNL6, A2LDB_DANRE;  A0JMM9, A2LDC_DANRE;  Q32LE4, GGCT_BOVIN ;
DR   O75223, GGCT_HUMAN ;  Q9D7X8, GGCT_MOUSE ;
//
ID   2.3.2.5
DE   Glutaminyl-peptide cyclotransferase.
AN   Glutaminyl cyclase.
AN   Glutaminyl-tRNA cyclotransferase.
CA   L-glutaminyl-peptide = 5-oxoprolyl-peptide + NH(3).
CC   -!- Involved in the formation of thyrotropin-releasing hormone and other
CC       biologically active peptides containing N-terminal pyroglutamyl
CC       residues.
CC   -!- The enzyme from papaya also acts on glutaminyl-tRNA.
DR   Q0V8G3, QPCTL_BOVIN;  Q9NXS2, QPCTL_HUMAN;  Q4R942, QPCTL_MACFA;
DR   Q8BH73, QPCTL_MOUSE;  Q84WV9, QPCT_ARATH ;  A7ISW2, QPCT_BOIDE ;
DR   A7ISW1, QPCT_BOIIR ;  Q9YIB5, QPCT_BOTJA ;  Q28120, QPCT_BOVIN ;
DR   P0CV92, QPCT_CROAT ;  Q54B14, QPCT_DICDI ;  Q90YA8, QPCT_GLOBL ;
DR   Q16769, QPCT_HUMAN ;  Q9CYK2, QPCT_MOUSE ;
//
ID   2.3.2.6
DE   Leucyltransferase.
AN   L/F transferase.
AN   Leucyl-tRNA--protein transferase.
AN   Leucyl/phenylalanyl-tRNA--protein transferase.
CA   L-leucyl-tRNA + protein = tRNA + L-leucyl-protein.
CF   Monovalent cation.
CC   -!- Also transfers phenylalanyl groups.
CC   -!- Peptides and proteins containing an N-terminal arginine, lysine or
CC       histidine residue can act as acceptors.
DR   Q6FDS1, LFTR_ACIAD ;  A0KJE0, LFTR_AERHH ;  B9JDP1, LFTR_AGRRK ;
DR   Q8UFR8, LFTR_AGRT5 ;  B9JVK2, LFTR_AGRVS ;  B2UNS0, LFTR_AKKM8 ;
DR   Q0VQ12, LFTR_ALCBS ;  Q0A7X8, LFTR_ALHEH ;  B6EIX7, LFTR_ALISL ;
DR   B8JDV1, LFTR_ANAD2 ;  Q2IP38, LFTR_ANADE ;  A7H8K2, LFTR_ANADF ;
DR   B4UEC9, LFTR_ANASK ;  Q3MCD0, LFTR_ANAVT ;  Q5P1A7, LFTR_AROAE ;
DR   A1K7M0, LFTR_AZOSB ;  C1DKZ4, LFTR_AZOVD ;  Q2KW47, LFTR_BORA1 ;
DR   Q7WGE6, LFTR_BORBR ;  Q7W4W8, LFTR_BORPA ;  A9I8M6, LFTR_BORPD ;
DR   Q89MA7, LFTR_BRAJA ;  A5EJD2, LFTR_BRASB ;  A4YTQ2, LFTR_BRASO ;
DR   B2S5D7, LFTR_BRUA1 ;  Q2YNP4, LFTR_BRUA2 ;  Q57DK4, LFTR_BRUAB ;
DR   C0RIN8, LFTR_BRUMB ;  P0A4S7, LFTR_BRUME ;  P0A4S8, LFTR_BRUSU ;
DR   B1YPI8, LFTR_BURA4 ;  Q1BWM2, LFTR_BURCA ;  B1K0S6, LFTR_BURCC ;
DR   A0K731, LFTR_BURCH ;  B4E8N6, LFTR_BURCJ ;  Q0BFQ8, LFTR_BURCM ;
DR   A9AJ16, LFTR_BURM1 ;  A3NUS3, LFTR_BURP0 ;  A3N927, LFTR_BURP6 ;
DR   B2JKL7, LFTR_BURP8 ;  B2T3H9, LFTR_BURPP ;  Q63TV3, LFTR_BURPS ;
DR   Q39GX3, LFTR_BURS3 ;  Q2SVM1, LFTR_BURTA ;  A4JE24, LFTR_BURVG ;
DR   Q13ZM1, LFTR_BURXL ;  A8FMG2, LFTR_CAMJ8 ;  A7H2P8, LFTR_CAMJD ;
DR   Q9PNI5, LFTR_CAMJE ;  A1W096, LFTR_CAMJJ ;  Q5HTZ5, LFTR_CAMJR ;
DR   B9KCU7, LFTR_CAMLR ;  B8GWN5, LFTR_CAUCN ;  Q9A741, LFTR_CAUCR ;
DR   B0SXA5, LFTR_CAUSK ;  B3PL51, LFTR_CELJU ;  B3EGK5, LFTR_CHLL2 ;
DR   B3QQ80, LFTR_CHLP8 ;  A1BEA5, LFTR_CHLPD ;  Q8KFI0, LFTR_CHLTE ;
DR   Q1QUS4, LFTR_CHRSD ;  Q7NX31, LFTR_CHRVO ;  A8AIJ8, LFTR_CITK8 ;
DR   A3DES1, LFTR_CLOTH ;  Q480P4, LFTR_COLP3 ;  Q0KBT2, LFTR_CUPNH ;
DR   Q472J4, LFTR_CUPPJ ;  B3R4T2, LFTR_CUPTR ;  B7K8N3, LFTR_CYAP7 ;
DR   Q47GS9, LFTR_DECAR ;  Q9RTP4, LFTR_DEIRA ;  B8FGA1, LFTR_DESAA ;
DR   C6BTW3, LFTR_DESAD ;  C0QI26, LFTR_DESAH ;  Q30ZK1, LFTR_DESDG ;
DR   C4XT58, LFTR_DESMR ;  Q6ALZ3, LFTR_DESPS ;  Q72BN2, LFTR_DESVH ;
DR   A1VDN2, LFTR_DESVV ;  A8LJB4, LFTR_DINSH ;  A7ZJV2, LFTR_ECO24 ;
DR   B7UMX6, LFTR_ECO27 ;  B7MHJ7, LFTR_ECO45 ;  B7LD77, LFTR_ECO55 ;
DR   Q8X5I5, LFTR_ECO57 ;  B5YT20, LFTR_ECO5E ;  B7NM92, LFTR_ECO7I ;
DR   B7MRU8, LFTR_ECO81 ;  B7M813, LFTR_ECO8A ;  C4ZQ11, LFTR_ECOBW ;
DR   B1X825, LFTR_ECODH ;  A7ZYI8, LFTR_ECOHS ;  A1A9C8, LFTR_ECOK1 ;
DR   Q0TJG5, LFTR_ECOL5 ;  Q8FJD1, LFTR_ECOL6 ;  B1IWN8, LFTR_ECOLC ;
DR   P0A8P1, LFTR_ECOLI ;  B7NAN6, LFTR_ECOLU ;  B6I8V6, LFTR_ECOSE ;
DR   B1LJX9, LFTR_ECOSM ;  Q1RE29, LFTR_ECOUT ;  C5BE98, LFTR_EDWI9 ;
DR   A4W8Q9, LFTR_ENT38 ;  Q6D3U2, LFTR_ERWCT ;  B2VC63, LFTR_ERWT9 ;
DR   B7LN53, LFTR_ESCF3 ;  A5FJI6, LFTR_FLAJ1 ;  A6H233, LFTR_FLAPJ ;
DR   Q7NLT7, LFTR_GLOVI ;  Q5FQE8, LFTR_GLUOX ;  A0M5U1, LFTR_GRAFK ;
DR   Q2SJK8, LFTR_HAHCH ;  A1WWV2, LFTR_HALHL ;  C4K842, LFTR_HAMD5 ;
DR   A9B6X1, LFTR_HERA2 ;  A4G7T5, LFTR_HERAR ;  Q0BZZ7, LFTR_HYPNA ;
DR   Q5R0B5, LFTR_IDILO ;  A6T104, LFTR_JANMA ;  Q28NS8, LFTR_JANSC ;
DR   B5XYA8, LFTR_KLEP3 ;  A6T6Y2, LFTR_KLEP7 ;  C1D7I2, LFTR_LARHH ;
DR   Q1MQQ4, LFTR_LAWIP ;  Q5X4E4, LFTR_LEGPA ;  A5ICS3, LFTR_LEGPC ;
DR   Q5ZUM5, LFTR_LEGPH ;  Q5WVS9, LFTR_LEGPL ;  Q04W85, LFTR_LEPBJ ;
DR   Q056R5, LFTR_LEPBL ;  B1Y1E6, LFTR_LEPCP ;  Q72W44, LFTR_LEPIC ;
DR   Q8F9T2, LFTR_LEPIN ;  Q2W3N1, LFTR_MAGSA ;  A0LCQ7, LFTR_MAGSM ;
DR   Q0AQ81, LFTR_MARMM ;  Q11HL3, LFTR_MESSB ;  Q607G8, LFTR_METCA ;
DR   A2SFU2, LFTR_METPP ;  Q1DCQ5, LFTR_MYXXD ;  Q5F5Z0, LFTR_NEIG1 ;
DR   B4RR38, LFTR_NEIG2 ;  A9M3H4, LFTR_NEIM0 ;  Q9JX50, LFTR_NEIMA ;
DR   Q9K1E9, LFTR_NEIMB ;  A1KRN6, LFTR_NEIMF ;  Q0AIB2, LFTR_NITEC ;
DR   Q82ST5, LFTR_NITEU ;  Q1QLB2, LFTR_NITHX ;  Q2Y5H5, LFTR_NITMU ;
DR   Q3J7Z7, LFTR_NITOC ;  Q3SRS3, LFTR_NITWN ;  B2J6L3, LFTR_NOSP7 ;
DR   Q8YQ68, LFTR_NOSS1 ;  Q2GA52, LFTR_NOVAD ;  A6X187, LFTR_OCHA4 ;
DR   B6JH85, LFTR_OLICO ;  A1B1I1, LFTR_PARDP ;  C6DF46, LFTR_PECCP ;
DR   Q3A2A9, LFTR_PELCD ;  Q3B5N7, LFTR_PELLD ;  B4SDP5, LFTR_PELPB ;
DR   B4RCS6, LFTR_PHEZH ;  Q7N6F5, LFTR_PHOLL ;  Q6LT10, LFTR_PHOPR ;
DR   Q12B43, LFTR_POLSJ ;  B4S3F9, LFTR_PROA2 ;  B4EV85, LFTR_PROMH ;
DR   Q48H69, LFTR_PSE14 ;  Q15TA1, LFTR_PSEA6 ;  A6V4G9, LFTR_PSEA7 ;
DR   B7UV24, LFTR_PSEA8 ;  Q02NA9, LFTR_PSEAB ;  Q9I0M1, LFTR_PSEAE ;
DR   Q1IBD5, LFTR_PSEE4 ;  Q4K9V1, LFTR_PSEF5 ;  C3JY59, LFTR_PSEFS ;
DR   Q3IH36, LFTR_PSEHT ;  A4XUY0, LFTR_PSEMY ;  A5W1H1, LFTR_PSEP1 ;
DR   Q3KA79, LFTR_PSEPF ;  B0KLX3, LFTR_PSEPG ;  Q88FS7, LFTR_PSEPK ;
DR   B1JBE5, LFTR_PSEPW ;  Q87ZS4, LFTR_PSESM ;  Q4ZRL0, LFTR_PSEU2 ;
DR   A4VLV3, LFTR_PSEU5 ;  Q4FUQ3, LFTR_PSYA2 ;  Q1QDP2, LFTR_PSYCK ;
DR   A1SWY4, LFTR_PSYIN ;  Q1LP24, LFTR_RALME ;  B2UFW4, LFTR_RALPJ ;
DR   Q8XYY9, LFTR_RALSO ;  B3PXY4, LFTR_RHIE6 ;  Q2K927, LFTR_RHIEC ;
DR   Q1MHI4, LFTR_RHIL3 ;  Q98NC4, LFTR_RHILO ;  B5ZMK3, LFTR_RHILW ;
DR   Q92QK2, LFTR_RHIME ;  C3MAB3, LFTR_RHISN ;  Q21VY7, LFTR_RHOFD ;
DR   Q2IVN3, LFTR_RHOP2 ;  Q07MA3, LFTR_RHOP5 ;  Q6N734, LFTR_RHOPA ;
DR   Q213K6, LFTR_RHOPB ;  Q137T4, LFTR_RHOPS ;  B3QH27, LFTR_RHOPT ;
DR   Q2RRK9, LFTR_RHORT ;  A3PKR6, LFTR_RHOS1 ;  Q3J1H1, LFTR_RHOS4 ;
DR   A4WSI3, LFTR_RHOS5 ;  B9KJU5, LFTR_RHOSK ;  Q165G5, LFTR_ROSDO ;
DR   Q1AX36, LFTR_RUBXD ;  Q21K28, LFTR_SACD2 ;  B5F138, LFTR_SALA4 ;
DR   A9MHZ9, LFTR_SALAR ;  Q57R46, LFTR_SALCH ;  B5FQ28, LFTR_SALDC ;
DR   B5QYN6, LFTR_SALEP ;  B5R8H3, LFTR_SALG2 ;  B4TD16, LFTR_SALHS ;
DR   B4T119, LFTR_SALNS ;  Q5PGJ6, LFTR_SALPA ;  A9N7Y5, LFTR_SALPB ;
DR   C0PXS2, LFTR_SALPC ;  B5BBS0, LFTR_SALPK ;  Q2S4B9, LFTR_SALRD ;
DR   B4TRR7, LFTR_SALSV ;  P67614, LFTR_SALTI ;  P67613, LFTR_SALTY ;
DR   A8GCE0, LFTR_SERP5 ;  A1S7A2, LFTR_SHEAM ;  B8E954, LFTR_SHEB2 ;
DR   A3D5E9, LFTR_SHEB5 ;  A6WP60, LFTR_SHEB8 ;  A9L4G0, LFTR_SHEB9 ;
DR   Q12N55, LFTR_SHEDO ;  Q081G8, LFTR_SHEFN ;  B0TQ11, LFTR_SHEHH ;
DR   A3QD88, LFTR_SHELP ;  Q8EDW8, LFTR_SHEON ;  A8H5L2, LFTR_SHEPA ;
DR   A4Y7L2, LFTR_SHEPC ;  B8CLI5, LFTR_SHEPW ;  A0KW20, LFTR_SHESA ;
DR   A8FUH7, LFTR_SHESH ;  Q0HJP0, LFTR_SHESM ;  Q0HVY6, LFTR_SHESR ;
DR   A1RIX6, LFTR_SHESW ;  B1KIC1, LFTR_SHEWM ;  B2TUJ4, LFTR_SHIB3 ;
DR   Q323L8, LFTR_SHIBS ;  Q32E04, LFTR_SHIDS ;  Q0T8P1, LFTR_SHIF8 ;
DR   P0A8P2, LFTR_SHIFL ;  Q3Z3N5, LFTR_SHISS ;  Q5LUP4, LFTR_SILPO ;
DR   Q1GGG4, LFTR_SILST ;  A6U825, LFTR_SINMW ;  A5V9E5, LFTR_SPHWW ;
DR   Q30TE4, LFTR_SULDN ;  Q2LQL0, LFTR_SYNAS ;  A0LE95, LFTR_SYNFM ;
DR   Q2JWL1, LFTR_SYNJA ;  Q2JMZ3, LFTR_SYNJB ;  P73571, LFTR_SYNY3 ;
DR   C5BIJ8, LFTR_TERTT ;  Q8DKJ8, LFTR_THEEB ;  B5YGC5, LFTR_THEYD ;
DR   Q31GL4, LFTR_THICR ;  Q3SH93, LFTR_THIDA ;  C4L944, LFTR_TOLAT ;
DR   A5F7F1, LFTR_VIBC3 ;  Q9KRA7, LFTR_VIBCH ;  C3LN57, LFTR_VIBCM ;
DR   Q5E3Y9, LFTR_VIBF1 ;  B5FG61, LFTR_VIBFM ;  A7N1L9, LFTR_VIBHB ;
DR   Q87QY1, LFTR_VIBPA ;  B7VM36, LFTR_VIBSL ;  Q1RS89, LFTR_VIBVU ;
DR   Q7MAC4, LFTR_WOLSU ;  Q8PL03, LFTR_XANAC ;  Q3BTY0, LFTR_XANC5 ;
DR   Q4UUK2, LFTR_XANC8 ;  B0RT37, LFTR_XANCB ;  Q8P996, LFTR_XANCP ;
DR   Q2P2R2, LFTR_XANOM ;  Q5GZR6, LFTR_XANOR ;  B2I9Y3, LFTR_XYLF2 ;
DR   Q9PDD3, LFTR_XYLFA ;  B0U6R3, LFTR_XYLFM ;  Q87DL5, LFTR_XYLFT ;
DR   A1JMD2, LFTR_YERE8 ;  A7FJZ0, LFTR_YERP3 ;  Q1CA93, LFTR_YERPA ;
DR   B2KA03, LFTR_YERPB ;  Q8ZGD2, LFTR_YERPE ;  A9R4Y8, LFTR_YERPG ;
DR   Q1CGE3, LFTR_YERPN ;  A4TN37, LFTR_YERPP ;  Q66CK7, LFTR_YERPS ;
DR   B1JRF9, LFTR_YERPY ;  Q5NP09, LFTR_ZYMMO ;
//
ID   2.3.2.7
DE   Aspartyltransferase.
CA   L-asparagine + hydroxylamine = NH(3) + beta-L-aspartylhydroxamate.
//
ID   2.3.2.8
DE   Arginyltransferase.
AN   Arginyl-tRNA--protein transferase.
CA   L-arginyl-tRNA + protein = tRNA + L-arginyl-protein.
CC   -!- Requires mercaptoethanol and a univalent cation.
CC   -!- Peptides and proteins containing an N-terminal glutamate, aspartate
CC       or cystine residue can act as acceptors.
DR   Q9ZT48, ATE1_ARATH ;  Q55EI0, ATE1_DICDI ;  O96539, ATE1_DROME ;
DR   O95260, ATE1_HUMAN ;  Q2PFX0, ATE1_MACFA ;  Q9Z2A5, ATE1_MOUSE ;
DR   O14133, ATE1_SCHPO ;  P16639, ATE1_YEAST ;  A1TRT1, ATE_ACIAC  ;
DR   Q6FDS2, ATE_ACIAD  ;  B7I7S8, ATE_ACIB5  ;  B2HUQ9, ATE_ACIBC  ;
DR   B0VTF8, ATE_ACIBS  ;  A3M311, ATE_ACIBT  ;  B0V8X8, ATE_ACIBY  ;
DR   B9MJA6, ATE_ACIET  ;  A1W7D8, ATE_ACISJ  ;  A0KJD9, ATE_AERHH  ;
DR   A4SNL5, ATE_AERS4  ;  B9JCW7, ATE_AGRRK  ;  Q8UG81, ATE_AGRT5  ;
DR   B9JV68, ATE_AGRVS  ;  Q0VQ13, ATE_ALCBS  ;  Q0A7X7, ATE_ALHEH  ;
DR   Q5P1A8, ATE_AROAE  ;  A8HXU1, ATE_AZOC5  ;  Q2KW46, ATE_BORA1  ;
DR   Q7WGE5, ATE_BORBR  ;  Q7W4W7, ATE_BORPA  ;  A9I8M3, ATE_BORPD  ;
DR   Q7VTR8, ATE_BORPE  ;  Q89K72, ATE_BRAJA  ;  A5EKJ1, ATE_BRASB  ;
DR   A4YWA5, ATE_BRASO  ;  B2S504, ATE_BRUA1  ;  Q2YNA4, ATE_BRUA2  ;
DR   Q57DZ4, ATE_BRUAB  ;  A9MAD7, ATE_BRUC2  ;  C0RI93, ATE_BRUMB  ;
DR   P63646, ATE_BRUME  ;  A5VPT9, ATE_BRUO2  ;  B0CL81, ATE_BRUSI  ;
DR   P63647, ATE_BRUSU  ;  B1YPI7, ATE_BURA4  ;  Q1BWM3, ATE_BURCA  ;
DR   B1K0S5, ATE_BURCC  ;  A0K730, ATE_BURCH  ;  B4E8N5, ATE_BURCJ  ;
DR   Q0BFQ9, ATE_BURCM  ;  A9AJX3, ATE_BURM1  ;  A3MJ99, ATE_BURM7  ;
DR   A2S373, ATE_BURM9  ;  Q62K46, ATE_BURMA  ;  A1V4A4, ATE_BURMS  ;
DR   A3NUS2, ATE_BURP0  ;  Q3JSS7, ATE_BURP1  ;  A3N926, ATE_BURP6  ;
DR   B2JKL8, ATE_BURP8  ;  B2T3H8, ATE_BURPP  ;  Q63TV2, ATE_BURPS  ;
DR   Q39GX4, ATE_BURS3  ;  Q2SVM0, ATE_BURTA  ;  A4JE23, ATE_BURVG  ;
DR   Q13ZM2, ATE_BURXL  ;  A8FM84, ATE_CAMJ8  ;  A7H303, ATE_CAMJD  ;
DR   Q9PNQ6, ATE_CAMJE  ;  A1W023, ATE_CAMJJ  ;  Q5HU66, ATE_CAMJR  ;
DR   B8GVD8, ATE_CAUCN  ;  Q9A7Z5, ATE_CAUCR  ;  B3PL52, ATE_CELJU  ;
DR   Q1QUS3, ATE_CHRSD  ;  Q7NX30, ATE_CHRVO  ;  Q480P3, ATE_COLP3  ;
DR   Q0KBT3, ATE_CUPNH  ;  Q472J5, ATE_CUPPJ  ;  B3R4T1, ATE_CUPTR  ;
DR   Q47GT0, ATE_DECAR  ;  A9BME3, ATE_DELAS  ;  A8LSL0, ATE_DINSH  ;
DR   A9HRQ0, ATE_GLUDA  ;  Q5FUV3, ATE_GLUOX  ;  Q0BTF8, ATE_GRABC  ;
DR   Q2SJK9, ATE_HAHCH  ;  A1WWV3, ATE_HALHL  ;  P59794, ATE_HELHP  ;
DR   A4G7T6, ATE_HERAR  ;  Q0C3S3, ATE_HYPNA  ;  A6T105, ATE_JANMA  ;
DR   Q28R42, ATE_JANSC  ;  Q04SK8, ATE_LEPBJ  ;  Q050N5, ATE_LEPBL  ;
DR   B1Y1E7, ATE_LEPCP  ;  Q72R21, ATE_LEPIC  ;  Q8F4R6, ATE_LEPIN  ;
DR   Q2W440, ATE_MAGSA  ;  A1U1G9, ATE_MARAV  ;  Q0APD6, ATE_MARMM  ;
DR   Q11JA2, ATE_MESSB  ;  B7KPZ2, ATE_METC4  ;  A9VY56, ATE_METEP  ;
DR   Q1H2E4, ATE_METFK  ;  B8IPM0, ATE_METNO  ;  B1ZJU3, ATE_METPB  ;
DR   A2SFU1, ATE_METPP  ;  B0UJ71, ATE_METS4  ;  Q82ST4, ATE_NITEU  ;
DR   Q1QL63, ATE_NITHX  ;  Q2Y5H6, ATE_NITMU  ;  Q3J7Z6, ATE_NITOC  ;
DR   Q3SRC0, ATE_NITWN  ;  Q2G9C7, ATE_NOVAD  ;  A6X1Z7, ATE_OCHA4  ;
DR   B6JGH2, ATE_OLICO  ;  A1B416, ATE_PARDP  ;  A7HX57, ATE_PARL1  ;
DR   B4RBQ2, ATE_PHEZH  ;  A1VN09, ATE_POLNA  ;  B1XV76, ATE_POLNS  ;
DR   Q12B44, ATE_POLSJ  ;  A4SWU6, ATE_POLSQ  ;  Q48H68, ATE_PSE14  ;
DR   Q15TA0, ATE_PSEA6  ;  A6V4G8, ATE_PSEA7  ;  B7UV23, ATE_PSEA8  ;
DR   Q02NB0, ATE_PSEAB  ;  Q9I0M0, ATE_PSEAE  ;  Q1IBD6, ATE_PSEE4  ;
DR   Q4K9V0, ATE_PSEF5  ;  C3JY60, ATE_PSEFS  ;  A4XUY1, ATE_PSEMY  ;
DR   A5W1H0, ATE_PSEP1  ;  Q3KA78, ATE_PSEPF  ;  B0KLX4, ATE_PSEPG  ;
DR   Q88FS6, ATE_PSEPK  ;  B1JBE6, ATE_PSEPW  ;  Q87ZS3, ATE_PSESM  ;
DR   Q4ZRK9, ATE_PSEU2  ;  A4VLV4, ATE_PSEU5  ;  Q1LP26, ATE_RALME  ;
DR   B2UFW5, ATE_RALPJ  ;  Q8XYZ0, ATE_RALSO  ;  Q2KA31, ATE_RHIEC  ;
DR   Q1MIV1, ATE_RHIL3  ;  Q983E4, ATE_RHILO  ;  B5ZX28, ATE_RHILW  ;
DR   Q92KF8, ATE_RHIME  ;  Q21VY8, ATE_RHOFD  ;  Q2IWT7, ATE_RHOP2  ;
DR   Q07M86, ATE_RHOP5  ;  Q6N6A7, ATE_RHOPA  ;  Q214I7, ATE_RHOPB  ;
DR   Q136V2, ATE_RHOPS  ;  B3QJI8, ATE_RHOPT  ;  Q2RTA0, ATE_RHORT  ;
DR   A3PJ90, ATE_RHOS1  ;  Q3J340, ATE_RHOS4  ;  B9KRL8, ATE_RHOSK  ;
DR   Q165K9, ATE_ROSDO  ;  Q21K29, ATE_SACD2  ;  A1S7A3, ATE_SHEAM  ;
DR   Q8EDW7, ATE_SHEON  ;  A4Y7L3, ATE_SHEPC  ;  A0KW19, ATE_SHESA  ;
DR   Q0HJP1, ATE_SHESM  ;  Q0HVY7, ATE_SHESR  ;  Q5LQC3, ATE_SILPO  ;
DR   Q1GIA1, ATE_SILST  ;  A6U7N6, ATE_SINMW  ;  Q1GWA7, ATE_SPHAL  ;
DR   P59795, ATE_SPHEL  ;  A5V8Y6, ATE_SPHWW  ;  B4SP02, ATE_STRM5  ;
DR   B2FTC1, ATE_STRMK  ;  C5BIJ7, ATE_TERTT  ;  Q3SH94, ATE_THIDA  ;
DR   C5CYP5, ATE_VARPS  ;  A1WNY2, ATE_VEREI  ;  A5F7F2, ATE_VIBC3  ;
DR   Q9KRA6, ATE_VIBCH  ;  C3LN58, ATE_VIBCM  ;  A7N1L8, ATE_VIBHB  ;
DR   Q87QY2, ATE_VIBPA  ;  Q8DAR7, ATE_VIBVU  ;  Q7MJ43, ATE_VIBVY  ;
DR   Q8PN34, ATE_XANAC  ;  Q3BW59, ATE_XANC5  ;  Q4US26, ATE_XANC8  ;
DR   B0RY43, ATE_XANCB  ;  Q8PBH8, ATE_XANCP  ;  Q2P5C8, ATE_XANOM  ;
DR   B2STA8, ATE_XANOP  ;  Q5H2F6, ATE_XANOR  ;  A7INB9, ATE_XANP2  ;
DR   B2I7M5, ATE_XYLF2  ;  Q9PEL0, ATE_XYLFA  ;  B0U219, ATE_XYLFM  ;
DR   Q87EJ8, ATE_XYLFT  ;
//
ID   2.3.2.9
DE   Agaritine gamma-glutamyltransferase.
CA   Agaritine + acceptor = 4-hydroxymethylphenylhydrazine + gamma-L-glutamyl-
CA   acceptor.
CC   -!- 4-hydroxyaniline, cyclohexylamine, 1-naphthylhydrazine and similar
CC       compounds can act as acceptors.
CC   -!- Also catalyzes the hydrolysis of agaritine.
//
ID   2.3.2.10
DE   UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase.
AN   Alanyl-transfer ribonucleate-uridine diphosphoacetylmuramoylpentapeptide
AN   transferase.
AN   UDP-N-acetylmuramoylpentapeptide lysine N(6)-alanyltransferase.
AN   Uridine diphosphoacetylmuramoylpentapeptide lysine N(6)-
AN   alanyltransferase.
CA   L-alanyl-tRNA + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-
CA   alanyl-D-alanine = tRNA + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N(6)-
CA   (L-alanyl)-L-lysyl-D-alanyl-D-alanine.
CC   -!- Also acts on L-seryl-tRNA.
//
ID   2.3.2.11
DE   Alanylphosphatidylglycerol synthase.
CA   L-alanyl-tRNA + phosphatidylglycerol = tRNA + 3-O-L-alanyl-1-
CA   O-phosphatidylglycerol.
//
ID   2.3.2.12
DE   Peptidyltransferase.
CA   Peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidyl(aminoacyl-
CA   tRNA(2)).
CC   -!- The enzyme is a ribozyme.
CC   -!- Two non-equivlant ribonucleoprotein subunits operate in non-concerted
CC       fashion in peptide elongation.
CC   -!- The small subunit forms the mRNA-binding machinery and decoding
CC       center, the large subunit performs the main ribosomal catalytic
CC       function in the peptidyl-transferase center.
//
ID   2.3.2.13
DE   Protein-glutamine gamma-glutamyltransferase.
AN   Fibrinoligase.
AN   Glutaminylpeptide gamma-glutamyltransferase.
AN   Polyamine transglutaminase.
AN   TGase.
AN   Transglutaminase.
CA   Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH(3).
CF   Calcium.
CC   -!- The gamma-carboxymide groups of peptide-bound glutamine residues act
CC       as acyl donors, and the 6-amino-groups of protein- and peptide-bound
CC       lysine residues act as acceptors, to give intra- and inter-molecular
CC       N(6)-(5-glutamyl)lysine crosslinks.
PR   PROSITE; PDOC00473;
DR   P52183, ANNU_SCHAM ;  P12260, F13A_BOVIN ;  P00488, F13A_HUMAN ;
DR   Q8BH61, F13A_MOUSE ;  O08619, F13A_RAT   ;  Q8GR90, TGAS_STRCJ ;
DR   P81453, TGAS_STRMB ;  C3P6X0, TGL_BACAA  ;  C3LI29, TGL_BACAC  ;
DR   A0RHX9, TGL_BACAH  ;  Q81MS1, TGL_BACAN  ;  B7JKT7, TGL_BACC0  ;
DR   B7IVK0, TGL_BACC2  ;  C1EPX7, TGL_BACC3  ;  B7H6V0, TGL_BACC4  ;
DR   B7HME8, TGL_BACC7  ;  A7GRZ1, TGL_BACCN  ;  B9IW43, TGL_BACCQ  ;
DR   Q819L3, TGL_BACCR  ;  Q635W3, TGL_BACCZ  ;  Q9K5W7, TGL_BACHD  ;
DR   Q6HEJ9, TGL_BACHK  ;  Q65FN2, TGL_BACLD  ;  A8FGT0, TGL_BACP2  ;
DR   P40746, TGL_BACSU  ;  A9VUC4, TGL_BACWK  ;  Q9GLK0, TGM1_CANFA ;
DR   P22735, TGM1_HUMAN ;  Q9JLF6, TGM1_MOUSE ;  P22758, TGM1_RABIT ;
DR   P23606, TGM1_RAT   ;  P51176, TGM2_BOVIN ;  P08587, TGM2_CAVCU ;
DR   Q01841, TGM2_CHICK ;  P21980, TGM2_HUMAN ;  P21981, TGM2_MOUSE ;
DR   P52181, TGM2_PAGMA ;  O95932, TGM3L_HUMAN;  A6QP57, TGM3_BOVIN ;
DR   Q08188, TGM3_HUMAN ;  Q08189, TGM3_MOUSE ;  D4A5U3, TGM3_RAT   ;
DR   P49221, TGM4_HUMAN ;  Q8BZH1, TGM4_MOUSE ;  Q99041, TGM4_RAT   ;
DR   O43548, TGM5_HUMAN ;  Q9D7I9, TGM5_MOUSE ;  Q96PF1, TGM7_HUMAN ;
DR   Q05187, TGMH_TACTR ;
//
ID   2.3.2.14
DE   D-alanine gamma-glutamyltransferase.
CA   L-glutamine + D-alanine = NH(3) + gamma-L-glutamyl-D-alanine.
CC   -!- D-phenylalanine and D-2-aminobutyrate can also act as acceptors, more
CC       slowly.
CC   -!- Also catalyzes some of the reactions of EC 2.3.2.2.
//
ID   2.3.2.15
DE   Glutathione gamma-glutamylcysteinyltransferase.
AN   Phytochelatin synthase.
CA   Glutathione + (Glu(-Cys))(n)-Gly = Gly + (Glu(-Cys))(n+1)-Gly.
DR   Q9S7Z3, PCS1_ARATH ;  Q2TSC7, PCS1_LOTJA ;  Q9SWW5, PCS1_WHEAT ;
DR   Q9ZWB7, PCS2_ARATH ;  Q2TE74, PCS2_LOTJA ;  Q2QKL5, PCS3_LOTJA ;
DR   Q10075, PCS_SCHPO  ;
//
ID   2.3.2.16
DE   Lipid II:glycine glycyltransferase.
CA   N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine-
CA   diphosphoundecaprenyl-N-acetylglucosamine + glycyl-tRNA =
CA   N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-(N(6)-glycyl)-D-alanyl-
CA   D-alanine-diphosphoundecaprenyl-N-acetylglucosamine + tRNA.
CC   -!- This enzyme from Staphylococcus aureus catalyzes the transfer of
CC       glycine from a charged tRNA to N-acetylmuramoyl-L-alanyl-D-
CC       isoglutaminyl-L-lysyl-D-alanyl-D-alanine-diphosphoundecaprenyl-N-
CC       acetylglucosamine (lipid II), attaching it to the N(6) of the
CC       L-lysine at position 3 of the pentapeptide.
CC   -!- This is the first step in the synthesis of the pentaglycine
CC       interpeptide bridge that is used in S.aureus for the crosslinking of
CC       different glycan strands to each other.
CC   -!- Four additional glycine residues are subsequently attached by
CC       EC 2.3.2.17 (FemA) and EC 2.3.2.18 (FemB).
//
ID   2.3.2.17
DE   N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N(6)-glycyl)-D-alanyl-D-
DE   alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine
DE   glycyltransferase.
CA   N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-(N(6)-glycyl)-D-alanyl-
CA   D-alanine-diphosphoundecaprenyl-N-acetylglucosamine + 2 glycyl-tRNA =
CA   N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-(N(6)-triglycyl)-D-
CA   alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine + 2 tRNA.
CC   -!- This enzyme catalyzes the successive transfer of two glycine moieties
CC       from charged tRNAs to N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-
CC       lysyl-(N(6)-glycyl)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-
CC       acetylglucosamine, attaching them to a glycine residue previously
CC       attached by EC 2.3.2.16 (FemX) to the N(6) of the L-lysine at
CC       position 3 of the pentapeptide.
CC   -!- This is the second step in the synthesis of the pentaglycine
CC       interpeptide bridge that is used by Staphylococcus aureus for the
CC       crosslinking of different glycan strands to each other.
CC   -!- The next step is catalyzed by EC 2.3.2.18 (FemB).
CC   -!- This enzyme is essential for methicillin resistance.
//
ID   2.3.2.18
DE   N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N(6)-triglycine)-D-alanyl-
DE   D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine
DE   glycyltransferase.
CA   N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-(N(6)-triglycyl)-D-
CA   alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine + 2 glycyl-
CA   tRNA = N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-(N(6)-
CA   pentaglycyl)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine
CA   + 2 tRNA.
CC   -!- This Staphylococcus aureus enzyme catalyzes the successive transfer
CC       of two glycine moieties from charged tRNAs to N-acetylmuramoyl-L-
CC       alanyl-D-isoglutaminyl-L-lysyl-(N(6)-triglycyl)-D-alanyl-D-alanine-
CC       diphosphoundecaprenyl-N-acetylglucosamine, attaching them to the
CC       three glycine molecules that were previously attached to the N(6) of
CC       the L-lysine at position 3 of the pentapeptide by EC 2.3.2.16 (FemX)
CC       and EC 2.3.2.17 (FemA).
CC   -!- This is the last step in the synthesis of the pentaglycine
CC       interpeptide bridge that is used in this organism for the
CC       crosslinking of different glycan strands to each other.
//
ID   2.3.3.1
DE   Citrate (Si)-synthase.
AN   (R)-citric synthase.
AN   Citrate condensing enzyme.
AN   Citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)->acetyl-CoA).
AN   Citrate oxaloacetate-lyase, CoA-acetylating.
AN   Citrate synthase.
AN   Citrate synthetase.
AN   Citric synthase.
AN   Citric-condensing enzyme.
AN   Citrogenase.
AN   Condensing enzyme.
AN   Oxalacetic transacetase.
AN   Oxaloacetate transacetase.
CA   Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA.
CC   -!- The stereospecificity of this enzyme is opposite to that of
CC       EC 2.3.3.3, which is found in some anaerobes.
CC   -!- Formerly EC 4.1.3.7.
PR   PROSITE; PDOC00422;
DR   Q17GM7, CISY1_AEDAE;  Q9LXS7, CISY1_ARATH;  Q10530, CISY1_MYCTU;
DR   P51037, CISY1_RHITR;  P00890, CISY1_YEAST;  Q16P20, CISY2_AEDAE;
DR   Q9LXS6, CISY2_ARATH;  P39120, CISY2_BACSU;  P63778, CISY2_MYCBO;
DR   P63777, CISY2_MYCTU;  P51038, CISY2_RHITR;  P08679, CISY2_YEAST;
DR   Q9SJH7, CISY3_ARATH;  P45858, CISY3_BACSU;  P43635, CISY3_YEAST;
DR   P20115, CISY4_ARATH;  Q9M1D3, CISY5_ARATH;  Q86AV6, CISYC_DICDI;
DR   Q553V1, CISYM_DICDI;  Q8MQU6, CISYP_DICDI;  O34002, CISY_ABDS2 ;
DR   P20901, CISY_ACEAC ;  P20902, CISY_ACIAN ;  Q0GNE1, CISY_AMBCR ;
DR   P51044, CISY_ASPNG ;  Q59136, CISY_ASTRI ;  P27660, CISY_BACCO ;
DR   P39119, CISY_BACSU ;  P51031, CISY_BARBA ;  Q59198, CISY_BARDO ;
DR   P51032, CISY_BAREL ;  P51033, CISY_BARHE ;  P51034, CISY_BARQU ;
DR   Q59258, CISY_BARTA ;  P51035, CISY_BARVB ;  P51036, CISY_BARVI ;
DR   Q29RK1, CISY_BOVIN ;  P94325, CISY_BRAJA ;  Q61JF9, CISY_CAEBR ;
DR   P34575, CISY_CAEEL ;  P79024, CISY_CANTR ;  P23007, CISY_CHICK ;
DR   P49298, CISY_CITMA ;  P42457, CISY_CORGL ;  P18789, CISY_COXBU ;
DR   Q7ZVY5, CISY_DANRE ;  O80433, CISY_DAUCA ;  Q9RWB2, CISY_DEIRA ;
DR   Q9W401, CISY_DROME ;  P0ABH8, CISY_ECOL6 ;  P0ABH7, CISY_ECOLI ;
DR   O00098, CISY_EMENI ;  P83372, CISY_FRAAN ;  Q0QHL3, CISY_GLOMM ;
DR   Q9ZN37, CISY_HELPJ ;  P56062, CISY_HELPY ;  O75390, CISY_HUMAN ;
DR   Q0GNE0, CISY_IGUIG ;  Q6S9V7, CISY_KATPE ;  A4H9H8, CISY_LEIBR ;
DR   A4HXU4, CISY_LEIIN ;  Q4QDX3, CISY_LEIMA ;  P0C1Z2, CISY_MACFA ;
DR   Q0QEL7, CISY_MESAU ;  Q9CZU6, CISY_MOUSE ;  P26491, CISY_MYCSM ;
DR   P34085, CISY_NEUCR ;  P00889, CISY_PIG   ;  P84543, CISY_POPEU ;
DR   P14165, CISY_PSEAE ;  Q53554, CISY_PYRFU ;  Q8VHF5, CISY_RAT   ;
DR   O33915, CISY_RHIME ;  Q59732, CISY_RICAE ;  Q59730, CISY_RICAK ;
DR   P51039, CISY_RICAU ;  Q59734, CISY_RICBE ;  Q1RGV8, CISY_RICBR ;
DR   P51041, CISY_RICCA ;  P51042, CISY_RICCN ;  P51040, CISY_RICFE ;
DR   Q59741, CISY_RICHE ;  Q59742, CISY_RICJA ;  Q59748, CISY_RICMA ;
DR   Q59759, CISY_RICPA ;  P09948, CISY_RICPR ;  Q59768, CISY_RICRH ;
DR   Q59778, CISY_RICSI ;  Q59776, CISY_RICSL ;  P51043, CISY_RICTY ;
DR   O68883, CISY_SALTY ;  Q10306, CISY_SCHPO ;  Q43175, CISY_SOLTU ;
DR   P20903, CISY_STRHY ;  Q59939, CISY_STRMU ;  P80148, CISY_SULSO ;
DR   Q59977, CISY_SYNY3 ;  Q6S9V5, CISY_TETAD ;  Q4S5X1, CISY_TETNG ;
DR   P24118, CISY_TETTH ;  P21553, CISY_THEAC ;  P51045, CISY_THIFE ;
DR   Q6S9V9, CISY_THUAL ;  Q6S9V8, CISY_THUOB ;  Q7ZWZ5, CISY_XENLA ;
DR   Q28DK1, CISY_XENTR ;  Q6S9V6, CISY_XIPGL ;  P49299, CYSZ_CUCMA ;
//
ID   2.3.3.2
DE   Decylcitrate synthase.
AN   (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate oxaloacetate-lyase (CoA-
AN   acylating).
AN   2-decylcitrate synthase.
CA   Lauroyl-CoA + H(2)O + oxaloacetate = (2S,3S)-2-hydroxytridecane-1,2,3-
CA   tricarboxylate + CoA.
CC   -!- Formerly EC 4.1.3.23.
//
ID   2.3.3.3
DE   Citrate (Re)-synthase.
AN   (R)-citrate synthase.
AN   Citrate oxaloacetate-lyase ((pro-3R)-CH(2)COO(-)->acetyl-CoA).
AN   Re-citrate-synthase.
CA   Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA.
CC   -!- This enzyme is inactivated by oxygen and is found in some anaerobes.
CC   -!- Its stereospecificity is opposite to that of EC 2.3.3.1.
CC   -!- Formerly EC 4.1.3.28.
//
ID   2.3.3.4
DE   Decylhomocitrate synthase.
AN   2-decylhomocitrate synthase.
AN   3-hydroxytetradecane-1,3,4-tricarboxylate 2-oxoglutarate-lyase (CoA-
AN   acylating).
CA   Dodecanoyl-CoA + H(2)O + 2-oxoglutarate = (3S,4S)-3-hydroxytetradecane-
CA   1,3,4-tricarboxylate + CoA.
CC   -!- Decanoyl-CoA can act instead of dodecanoyl-CoA, but 2-oxoglutarate
CC       cannot be replaced by oxaloacetate or pyruvate.
CC   -!- Formerly EC 4.1.3.29.
//
ID   2.3.3.5
DE   2-methylcitrate synthase.
AN   2-methylcitrate oxaloacetate-lyase.
AN   MCS.
AN   Methylcitrate synthase.
AN   Methylcitrate synthetase.
CA   Propanoyl-CoA + H(2)O + oxaloacetate = (2R,3S)-2-hydroxybutane-1,2,3-
CA   tricarboxylate + CoA.
CC   -!- The enzyme acts on acetyl-CoA, propanoyl-CoA, butanoyl-CoA and
CC       pentanoyl-CoA.
CC   -!- The relative rate of condensation of acetyl-CoA and oxaloacetate is
CC       140% of that of propanoyl-CoA and oxaloacetate, but the enzyme has
CC       been separated from EC 2.3.3.1.
CC   -!- Oxaloacetate cannot be replaced by glyoxylate, pyruvate or
CC       2-oxoglutarate.
CC   -!- Formerly EC 4.1.3.31.
PR   PROSITE; PDOC00422;
DR   P45858, CISY3_BACSU;  Q8NSH7, PRPC1_CORGL;  Q8NSL1, PRPC2_CORGL;
DR   P31660, PRPC_ECOLI ;  Q9TEM3, PRPC_EMENI ;  Q56063, PRPC_SALTY ;
//
ID   2.3.3.6
DE   2-ethylmalate synthase.
AN   (R)-2-ethylmalate 2-oxobutanoyl-lyase (CoA-acetylating).
AN   2-ethylmalate-3-hydroxybutanedioate synthase.
AN   Propylmalate synthase.
AN   Propylmalic synthase.
CA   Acetyl-CoA + H(2)O + 2-oxobutanoate = (R)-2-ethylmalate + CoA.
CC   -!- Also acts on (R)-2-(n-propyl)-malate.
CC   -!- Formerly EC 4.1.3.33.
//
ID   2.3.3.7
DE   3-ethylmalate synthase.
AN   2-ethyl-3-hydroxybutanedioate synthase.
AN   3-ethylmalate glyoxylate-lyase (CoA-butanoylating).
CA   Butanoyl-CoA + H(2)O + glyoxylate = 3-ethylmalate + CoA.
CC   -!- Formerly EC 4.1.3.10.
//
ID   2.3.3.8
DE   ATP citrate synthase.
AN   Acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-
AN   phosphorylating).
AN   Adenosine triphosphate citrate lyase.
AN   ATP citrate (pro-S)-lyase.
AN   ATP-citrate (pro-S-)-lyase.
AN   ATP-citric lyase.
AN   ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP-
AN   dephosphorylating).
AN   Citrate cleavage enzyme.
AN   Citrate-ATP lyase.
AN   Citric cleavage enzyme.
CA   ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA.
CC   -!- The enzyme can be dissociated into components, two of which are
CC       identical with EC 4.1.3.34 and EC 6.2.1.18.
CC   -!- Formerly EC 4.1.3.8.
PR   PROSITE; PDOC00335;
DR   Q8X097, ACL1_NEUCR ;  Q9P7W3, ACL1_SCHPO ;  O93988, ACL1_SORMK ;
DR   O13907, ACL2_SCHPO ;  Q9SGY2, ACLA1_ARATH;  Q53JY8, ACLA1_ORYSJ;
DR   O22718, ACLA2_ARATH;  Q2QZ86, ACLA2_ORYSJ;  O80526, ACLA3_ARATH;
DR   Q2QNG7, ACLA3_ORYSJ;  Q9C522, ACLB1_ARATH;  Q93VT8, ACLB1_ORYSJ;
DR   Q9FGX1, ACLB2_ARATH;  Q32PF2, ACLY_BOVIN ;  P53585, ACLY_CAEEL ;
DR   Q54YA0, ACLY_DICDI ;  P53396, ACLY_HUMAN ;  Q91V92, ACLY_MOUSE ;
DR   P16638, ACLY_RAT   ;  Q2TCH3, ACLY_SHEEP ;
//
ID   2.3.3.9
DE   Malate synthase.
AN   Glyoxylate transacetase.
AN   Glyoxylate transacetylase.
AN   Glyoxylic transacetase.
AN   L-malate glyoxylate-lyase (CoA-acetylating).
AN   Malate condensing enzyme.
AN   Malate synthetase.
AN   Malic synthetase.
AN   Malic-condensing enzyme.
CA   Acetyl-CoA + H(2)O + glyoxylate = (S)-malate + CoA.
CC   -!- Formerly EC 4.1.3.2.
PR   PROSITE; PDOC00441;
DR   Q10663, GCP_CAEEL  ;  P13244, MASY_BRANA ;  Q02216, MASY_CANTR ;
DR   P24571, MASY_CUCMA ;  P08216, MASY_CUCSA ;  Q8T2K9, MASY_DICDI ;
DR   P08997, MASY_ECOLI ;  P28344, MASY_EMENI ;  P17432, MASY_GOSHI ;
DR   P49081, MASY_MAIZE ;  P95329, MASY_MYXXD ;  P28345, MASY_NEUCR ;
DR   P21360, MASY_PICAN ;  Q43827, MASY_RAPSA ;  P17815, MASY_RICCO ;
DR   P45458, MASY_SOYBN ;  P77947, MASY_STRAE ;  Q9ZH77, MASY_STRCL ;
DR   A6ZRW6, MASY_YEAS7 ;  P30952, MASY_YEAST ;  Q88AB2, MASZ1_PSESM;
DR   Q87Z72, MASZ2_PSESM;  B9JG75, MASZ_AGRRK ;  Q8UJ85, MASZ_AGRT5 ;
DR   B9JXY6, MASZ_AGRVS ;  Q0A845, MASZ_ALHEH ;  Q5P811, MASZ_AROAE ;
DR   Q9KB03, MASZ_BACHD ;  Q7WR61, MASZ_BORBR ;  Q7W294, MASZ_BORPA ;
DR   A9IHH4, MASZ_BORPD ;  Q7VT71, MASZ_BORPE ;  Q89UE3, MASZ_BRAJA ;
DR   A4YM47, MASZ_BRASO ;  B2S793, MASZ_BRUA1 ;  Q2YRK5, MASZ_BRUA2 ;
DR   Q57BM8, MASZ_BRUAB ;  A9M752, MASZ_BRUC2 ;  C0RES0, MASZ_BRUMB ;
DR   Q8YIR3, MASZ_BRUME ;  A5VS09, MASZ_BRUO2 ;  A9WWC9, MASZ_BRUSI ;
DR   Q8FZ50, MASZ_BRUSU ;  Q13YU3, MASZ_BURXL ;  Q1QSR0, MASZ_CHRSD ;
DR   Q8FNB3, MASZ_COREF ;  P42450, MASZ_CORGL ;  A9BRF0, MASZ_DELAS ;
DR   Q8FDN6, MASZ_ECOL6 ;  P37330, MASZ_ECOLI ;  Q5KZR8, MASZ_GEOKA ;
DR   C5D2K6, MASZ_GEOSW ;  A4IN50, MASZ_GEOTN ;  A1U1Q6, MASZ_MARAV ;
DR   Q11BE3, MASZ_MESSB ;  A0QGM8, MASZ_MYCA1 ;  B1MB69, MASZ_MYCA9 ;
DR   P0A5J5, MASZ_MYCBO ;  A1KJP9, MASZ_MYCBP ;  C1APB4, MASZ_MYCBT ;
DR   A4TAC4, MASZ_MYCGI ;  B8ZSN3, MASZ_MYCLB ;  O32913, MASZ_MYCLE ;
DR   B2HSY2, MASZ_MYCMM ;  Q73ZQ2, MASZ_MYCPA ;  A3Q0E7, MASZ_MYCSJ ;
DR   A1UGU7, MASZ_MYCSK ;  Q1B860, MASZ_MYCSS ;  A5U3K4, MASZ_MYCTA ;
DR   P0A5J4, MASZ_MYCTU ;  A0PSI5, MASZ_MYCUA ;  A1T9P9, MASZ_MYCVP ;
DR   Q1QHK3, MASZ_NITHX ;  Q3SNX3, MASZ_NITWN ;  Q5YWU1, MASZ_NOCFA ;
DR   A6WYD2, MASZ_OCHA4 ;  A6UYU5, MASZ_PSEA7 ;  B7V467, MASZ_PSEA8 ;
DR   Q02TT1, MASZ_PSEAB ;  Q9I636, MASZ_PSEAE ;  Q4K4S5, MASZ_PSEF5 ;
DR   O05137, MASZ_PSEFL ;  Q3K5N4, MASZ_PSEPF ;  Q88QX8, MASZ_PSEPK ;
DR   B3PWJ0, MASZ_RHIE6 ;  Q2KE51, MASZ_RHIEC ;  Q1MNB0, MASZ_RHIL3 ;
DR   Q98DK4, MASZ_RHILO ;  Q937W7, MASZ_RHILV ;  B5ZVA2, MASZ_RHILW ;
DR   Q92TA4, MASZ_RHIME ;  C3MBD2, MASZ_RHISN ;  C0ZZZ0, MASZ_RHOE4 ;
DR   Q9AE55, MASZ_RHOFA ;  Q2J0A5, MASZ_RHOP2 ;  Q6N234, MASZ_RHOPA ;
DR   Q13BC6, MASZ_RHOPS ;  B3QKU1, MASZ_RHOPT ;  P59663, MASZ_SHIFL ;
DR   A6UEL4, MASZ_SINMW ;  C5CJB5, MASZ_VARPS ;  P21826, MASZ_YEAST ;
//
ID   2.3.3.10
DE   Hydroxymethylglutaryl-CoA synthase.
AN   (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-
AN   acetylating).
AN   3-hydroxy-3-methylglutaryl CoA synthetase.
AN   3-hydroxy-3-methylglutaryl coenzyme A synthase.
AN   3-hydroxy-3-methylglutaryl coenzyme A synthetase.
AN   3-hydroxy-3-methylglutaryl-CoA synthase.
AN   3-hydroxy-3-methylglutaryl-coenzyme A synthase.
AN   Acetoacetyl coenzyme A transacetase.
AN   Beta-hydroxy-beta-methylglutaryl-CoA synthase.
AN   HMG-CoA synthase.
AN   Hydroxymethylglutaryl coenzyme A synthase.
AN   Hydroxymethylglutaryl coenzyme alpha-condensing enzyme.
CA   Acetyl-CoA + H(2)O + acetoacetyl-CoA = (S)-3-hydroxy-3-methylglutaryl-CoA
CA   + CoA.
CC   -!- Formerly EC 4.1.3.5.
PR   PROSITE; PDOC00942;
DR   P54961, HMCS1_BLAGE;  P23228, HMCS1_CHICK;  P13704, HMCS1_CRIGR;
DR   Q01581, HMCS1_HUMAN;  Q8JZK9, HMCS1_MOUSE;  Q5R7Z9, HMCS1_PONAB;
DR   P17425, HMCS1_RAT  ;  P54870, HMCS2_BLAGE;  Q2KIE6, HMCS2_BOVIN;
DR   P54868, HMCS2_HUMAN;  P54869, HMCS2_MOUSE;  O02734, HMCS2_PIG  ;
DR   P22791, HMCS2_RAT  ;  P54872, HMCSA_DICDI;  Q86HL5, HMCSB_DICDI;
DR   P54873, HMCS_ARATH ;  P54871, HMCS_CAEEL ;  P54874, HMCS_SCHPO ;
DR   P54839, HMCS_YEAST ;
//
ID   2.3.3.11
DE   2-hydroxyglutarate synthase.
AN   2-hydroxyglutarate glyoxylate-lyase (CoA-propanoylating).
AN   2-hydroxyglutaratic synthetase.
AN   2-hydroxyglutaric synthetase.
AN   Alpha-hydroxyglutarate synthase.
AN   Hydroxyglutarate synthase.
CA   Propanoyl-CoA + H(2)O + glyoxylate = 2-hydroxyglutarate + CoA.
CC   -!- Formerly EC 4.1.3.9.
//
ID   2.3.3.12
DE   3-propylmalate synthase.
AN   3-(n-propyl)-malate synthase.
AN   3-propylmalate glyoxylate-lyase (CoA-pentanoylating).
AN   Beta-n-propylmalate synthase.
AN   n-propylmalate synthase.
CA   Pentanoyl-CoA + H(2)O + glyoxylate = 3-propylmalate + CoA.
CC   -!- Formerly EC 4.1.3.11.
//
ID   2.3.3.13
DE   2-isopropylmalate synthase.
AN   3-carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase
AN   (CoA-acetylating).
AN   Alpha-IPM synthetase.
AN   Alpha-isopropylmalate synthase.
AN   Alpha-isopropylmalate synthetase.
AN   Alpha-isopropylmalic synthetase.
AN   Isopropylmalate synthase.
AN   Isopropylmalate synthetase.
CA   Acetyl-CoA + 3-methyl-2-oxobutanoate + H(2)O = (2S)-2-isopropylmalate +
CA   CoA.
CF   Potassium.
CC   -!- Formerly EC 4.1.3.12.
PR   PROSITE; PDOC00643;
PR   PROSITE; PDOC50991;
DR   Q9LPR4, LEU11_ARATH;  A8FFW5, LEU11_BACP2;  Q8XXP1, LEU11_RALSO;
DR   Q8RDK3, LEU11_THETN;  Q31I16, LEU11_THICR;  Q9C550, LEU12_ARATH;
DR   A8FAK7, LEU12_BACP2;  Q8XSZ5, LEU12_RALSO;  Q8RCF9, LEU12_THETN;
DR   Q31EF5, LEU12_THICR;  O04973, LEU1A_SOLPN;  O04974, LEU1B_SOLPN;
DR   A1TRT4, LEU1_ACIAC ;  B9MA32, LEU1_ACIET ;  C7M0E4, LEU1_ACIFD ;
DR   A1W6T7, LEU1_ACISJ ;  A0KGM9, LEU1_AERHH ;  A4SR62, LEU1_AERS4 ;
DR   Q8UD63, LEU1_AGRT5 ;  Q0VLR3, LEU1_ALCBS ;  B6ELK0, LEU1_ALISL ;
DR   Q3MBA3, LEU1_ANAVT ;  B7GH19, LEU1_ANOFW ;  O67862, LEU1_AQUAE ;
DR   A8ES07, LEU1_ARCB4 ;  O30020, LEU1_ARCFU ;  Q5NXN2, LEU1_AROAE ;
DR   A1R6V4, LEU1_ARTAT ;  B8H8Q9, LEU1_ARTCA ;  A0JX36, LEU1_ARTS2 ;
DR   A1KBD3, LEU1_AZOSB ;  C1DE40, LEU1_AZOVD ;  A7Z7B8, LEU1_BACA2 ;
DR   C3P4Z6, LEU1_BACAA ;  C3L9Q7, LEU1_BACAC ;  A0RBL2, LEU1_BACAH ;
DR   Q81T68, LEU1_BACAN ;  B7JFY5, LEU1_BACC0 ;  Q73BA0, LEU1_BACC1 ;
DR   C1EMA9, LEU1_BACC3 ;  A7GMU1, LEU1_BACCN ;  B9IUZ0, LEU1_BACCQ ;
DR   Q63DX8, LEU1_BACCZ ;  Q9K8E8, LEU1_BACHD ;  Q6HLF3, LEU1_BACHK ;
DR   Q65GI8, LEU1_BACLD ;  Q5WEN3, LEU1_BACSK ;  P94565, LEU1_BACSU ;
DR   A9VLG7, LEU1_BACWK ;  B7GT76, LEU1_BIFLS ;  Q7VQJ6, LEU1_BLOFL ;
DR   Q493R0, LEU1_BLOPB ;  A9HW07, LEU1_BORPD ;  Q89GB0, LEU1_BRAJA ;
DR   A5EP79, LEU1_BRASB ;  A4YZ76, LEU1_BRASO ;  C0Z9C8, LEU1_BREBN ;
DR   Q8YIJ3, LEU1_BRUME ;  Q8FZC4, LEU1_BRUSU ;  Q9ZEY8, LEU1_BUCAI ;
DR   O85063, LEU1_BUCAP ;  Q89A49, LEU1_BUCBP ;  Q5WQ01, LEU1_BUCCC ;
DR   O85070, LEU1_BUCDN ;  Q9EVG4, LEU1_BUCML ;  P58898, LEU1_BUCPS ;
DR   P48571, LEU1_BUCRP ;  O31287, LEU1_BUCTS ;  Q9EVH6, LEU1_BUCUE ;
DR   Q9EVE3, LEU1_BUCUL ;  Q9EVH0, LEU1_BUCUM ;  Q9EVI8, LEU1_BUCUN ;
DR   B1YTR7, LEU1_BURA4 ;  Q1BV03, LEU1_BURCA ;  B1JVQ1, LEU1_BURCC ;
DR   A0K933, LEU1_BURCH ;  B4E5N2, LEU1_BURCJ ;  Q0BDB9, LEU1_BURCM ;
DR   A9AJN4, LEU1_BURM1 ;  A3NT94, LEU1_BURP0 ;  Q3JUB9, LEU1_BURP1 ;
DR   A3N7K7, LEU1_BURP6 ;  B2JDN6, LEU1_BURP8 ;  B2SXZ9, LEU1_BURPP ;
DR   Q63VP3, LEU1_BURPS ;  Q39ED5, LEU1_BURS3 ;  A4JGE0, LEU1_BURVG ;
DR   Q13WM0, LEU1_BURXL ;  A7ZES2, LEU1_CAMC1 ;  A0RQK7, LEU1_CAMFF ;
DR   A7I0N8, LEU1_CAMHC ;  A8FP35, LEU1_CAMJ8 ;  A7H667, LEU1_CAMJD ;
DR   Q9PLV9, LEU1_CAMJE ;  A1W1X2, LEU1_CAMJJ ;  Q5HS76, LEU1_CAMJR ;
DR   Q3AEQ5, LEU1_CARHZ ;  C7QJN7, LEU1_CATAD ;  B8H607, LEU1_CAUCN ;
DR   Q9A823, LEU1_CAUCR ;  B0T0G9, LEU1_CAUSK ;  Q7P0H2, LEU1_CHRVO ;
DR   A8ALM5, LEU1_CITK8 ;  A5CRB9, LEU1_CLAM3 ;  B0RCQ8, LEU1_CLAMS ;
DR   Q97MC5, LEU1_CLOAB ;  B8I1T7, LEU1_CLOCE ;  B9E371, LEU1_CLOK1 ;
DR   A5MZ76, LEU1_CLOK5 ;  E3PVH7, LEU1_CLOSD ;  A3DF94, LEU1_CLOTH ;
DR   Q8FU05, LEU1_COREF ;  A4QAP0, LEU1_CORGB ;  P42455, LEU1_CORGL ;
DR   Q0KCT8, LEU1_CUPNH ;  Q473V1, LEU1_CUPPJ ;  B2AHM5, LEU1_CUPTR ;
DR   B1WQQ4, LEU1_CYAA5 ;  B7KJX8, LEU1_CYAP7 ;  B7JYP4, LEU1_CYAP8 ;
DR   P85362, LEU1_CYCRE ;  Q47BI0, LEU1_DECAR ;  Q9RUA9, LEU1_DEIRA ;
DR   B1I1Y1, LEU1_DESAP ;  Q24PE3, LEU1_DESHY ;  C4XPA8, LEU1_DESMR ;
DR   A4J181, LEU1_DESRM ;  B8DM91, LEU1_DESVM ;  B5YEF4, LEU1_DICT6 ;
DR   B8E2W9, LEU1_DICTD ;  A7ZHG6, LEU1_ECO24 ;  B7UIC4, LEU1_ECO27 ;
DR   B7MAJ9, LEU1_ECO45 ;  B7LFU5, LEU1_ECO55 ;  Q8X9Z8, LEU1_ECO57 ;
DR   B5YZB0, LEU1_ECO5E ;  B7NHI2, LEU1_ECO7I ;  B7MNT2, LEU1_ECO81 ;
DR   B7M119, LEU1_ECO8A ;  C4ZPZ7, LEU1_ECOBW ;  A7ZW25, LEU1_ECOHS ;
DR   A1A7C2, LEU1_ECOK1 ;  Q0TLR5, LEU1_ECOL5 ;  Q8FL75, LEU1_ECOL6 ;
DR   B1IRA4, LEU1_ECOLC ;  P09151, LEU1_ECOLI ;  B7N7U9, LEU1_ECOLU ;
DR   B6HZ24, LEU1_ECOSE ;  B1LG11, LEU1_ECOSM ;  Q1RGC3, LEU1_ECOUT ;
DR   C5B7R4, LEU1_EDWI9 ;  A4W6H9, LEU1_ENT38 ;  A7MIC5, LEU1_ENTS8 ;
DR   Q6D0G8, LEU1_ERWCT ;  B2VDA7, LEU1_ERWT9 ;  B7LWE2, LEU1_ESCF3 ;
DR   A8L551, LEU1_FRASN ;  Q5KWJ3, LEU1_GEOKA ;  D3EBC1, LEU1_GEOS4 ;
DR   Q8RL85, LEU1_GEOSE ;  C5D5M0, LEU1_GEOSW ;  A4IRH8, LEU1_GEOTN ;
DR   Q7NI93, LEU1_GLOVI ;  Q4QLS4, LEU1_HAEI8 ;  A5UD85, LEU1_HAEIE ;
DR   P43861, LEU1_HAEIN ;  Q0I2G1, LEU1_HAES1 ;  B0USF6, LEU1_HAES2 ;
DR   B8CX21, LEU1_HALOH ;  Q7VH30, LEU1_HELHP ;  B0TCR1, LEU1_HELMI ;
DR   D8J0Q1, LEU1_HERSS ;  A8AB61, LEU1_IGNH4 ;  A6WDF2, LEU1_KINRD ;
DR   B5Y1W2, LEU1_KLEP3 ;  A6T4L9, LEU1_KLEP7 ;  B2GHT7, LEU1_KOCRD ;
DR   Q02141, LEU1_LACLA ;  Q02YX5, LEU1_LACLS ;  Q6AED3, LEU1_LEIXX ;
DR   B1XYA8, LEU1_LEPCP ;  Q72RL9, LEU1_LEPIC ;  Q8F445, LEU1_LEPIN ;
DR   Q92A28, LEU1_LISIN ;  C1KWT1, LEU1_LISMC ;  Q71Y35, LEU1_LISMF ;
DR   B8DBU4, LEU1_LISMH ;  Q8Y5R9, LEU1_LISMO ;  A0AK92, LEU1_LISW6 ;
DR   B1HR98, LEU1_LYSSC ;  A0LBW3, LEU1_MAGSM ;  A6VSA9, LEU1_MARMS ;
DR   Q8THA5, LEU1_METAC ;  Q605K7, LEU1_METCA ;  B3DX88, LEU1_METI4 ;
DR   Q58595, LEU1_METJA ;  Q8TYB1, LEU1_METKA ;  P58968, LEU1_METMA ;
DR   B8IHS8, LEU1_METNO ;  B1ZDN3, LEU1_METPB ;  A2SHL8, LEU1_METPP ;
DR   O27525, LEU1_METTH ;  P94907, LEU1_MICAE ;  B0JGK2, LEU1_MICAN ;
DR   Q7TVV6, LEU1_MYCBO ;  Q9CB76, LEU1_MYCLE ;  P96420, LEU1_MYCTU ;
DR   A0PVE6, LEU1_MYCUA ;  Q5F8D4, LEU1_NEIG1 ;  Q9JUK6, LEU1_NEIMA ;
DR   Q9JZG1, LEU1_NEIMB ;  A1KTV6, LEU1_NEIMF ;  Q0AGN5, LEU1_NITEC ;
DR   Q820M0, LEU1_NITEU ;  Q1QJV3, LEU1_NITHX ;  Q2YBW0, LEU1_NITMU ;
DR   Q3J877, LEU1_NITOC ;  A6Q4V5, LEU1_NITSB ;  Q3SQ49, LEU1_NITWN ;
DR   Q5YVA5, LEU1_NOCFA ;  P48575, LEU1_NOSS1 ;  Q8EN67, LEU1_OCEIH ;
DR   B6JB87, LEU1_OLICO ;  E1QWZ1, LEU1_OLSUV ;  A6LDN1, LEU1_PARD8 ;
DR   A7HP03, LEU1_PARL1 ;  Q9CJN5, LEU1_PASMU ;  C6DEV8, LEU1_PECCP ;
DR   A5D4W0, LEU1_PELTS ;  Q7N129, LEU1_PHOLL ;  Q6LV24, LEU1_PHOPR ;
DR   A1VN06, LEU1_POLNA ;  B1XUJ3, LEU1_POLNS ;  Q12B47, LEU1_POLSJ ;
DR   A4SXR0, LEU1_POLSQ ;  A3PDH0, LEU1_PROM0 ;  A2C3L7, LEU1_PROM1 ;
DR   A8G5D5, LEU1_PROM2 ;  A2C859, LEU1_PROM3 ;  A9BB43, LEU1_PROM4 ;
DR   A2BX52, LEU1_PROM5 ;  Q31AF9, LEU1_PROM9 ;  Q7VBG1, LEU1_PROMA ;
DR   B4F194, LEU1_PROMH ;  Q7TUV5, LEU1_PROMM ;  Q7V121, LEU1_PROMP ;
DR   A2BRP4, LEU1_PROMS ;  Q46K01, LEU1_PROMT ;  Q48LY5, LEU1_PSE14 ;
DR   Q15QR4, LEU1_PSEA6 ;  A6V0X2, LEU1_PSEA7 ;  Q9HXK5, LEU1_PSEAE ;
DR   Q1I5K2, LEU1_PSEE4 ;  Q4K6V7, LEU1_PSEF5 ;  C3K1K7, LEU1_PSEFS ;
DR   A4XY24, LEU1_PSEMY ;  A5VZB6, LEU1_PSEP1 ;  Q3K7C3, LEU1_PSEPF ;
DR   B0KRD9, LEU1_PSEPG ;  Q88P28, LEU1_PSEPK ;  B1JDI2, LEU1_PSEPW ;
DR   Q886Y1, LEU1_PSESM ;  Q4ZX14, LEU1_PSEU2 ;  A4VNV6, LEU1_PSEU5 ;
DR   A1SRG8, LEU1_PSYIN ;  Q9UZ08, LEU1_PYRAB ;  Q8ZW35, LEU1_PYRAE ;
DR   Q8U2A2, LEU1_PYRFU ;  Q1LPX2, LEU1_RALME ;  B2UJY9, LEU1_RALPJ ;
DR   A9WML8, LEU1_RENSM ;  Q1MDH6, LEU1_RHIL3 ;  Q98HN3, LEU1_RHILO ;
DR   Q9X7L2, LEU1_RHIME ;  Q7UI51, LEU1_RHOBA ;  Q21VZ1, LEU1_RHOFD ;
DR   Q2IUT4, LEU1_RHOP2 ;  Q07PI3, LEU1_RHOP5 ;  Q6N858, LEU1_RHOPA ;
DR   Q212A9, LEU1_RHOPB ;  Q138Z2, LEU1_RHOPS ;  B3QCX5, LEU1_RHOPT ;
DR   Q2RT17, LEU1_RHORT ;  A1AWA1, LEU1_RUTMC ;  B5F7U9, LEU1_SALA4 ;
DR   A9MQD8, LEU1_SALAR ;  Q57TE6, LEU1_SALCH ;  B5FI58, LEU1_SALDC ;
DR   B5R2K9, LEU1_SALEP ;  B5RGE4, LEU1_SALG2 ;  B4TJ72, LEU1_SALHS ;
DR   B4SU36, LEU1_SALNS ;  Q5PDG1, LEU1_SALPA ;  A9MZK0, LEU1_SALPB ;
DR   C0Q5H1, LEU1_SALPC ;  B5BLB5, LEU1_SALPK ;  D5HB86, LEU1_SALRM ;
DR   B4TWW1, LEU1_SALSV ;  Q8Z9I0, LEU1_SALTI ;  P15875, LEU1_SALTY ;
DR   O59736, LEU1_SCHPO ;  A8G9R1, LEU1_SERP5 ;  A1S2E0, LEU1_SHEAM ;
DR   B8E4K4, LEU1_SHEB2 ;  A3CZK5, LEU1_SHEB5 ;  A6WIB5, LEU1_SHEB8 ;
DR   A9KY13, LEU1_SHEB9 ;  Q12SE7, LEU1_SHEDO ;  Q07WG9, LEU1_SHEFN ;
DR   B0TQM0, LEU1_SHEHH ;  A3QIP0, LEU1_SHELP ;  Q8E9N2, LEU1_SHEON ;
DR   A8H9A1, LEU1_SHEPA ;  A4Y2M0, LEU1_SHEPC ;  B8CM39, LEU1_SHEPW ;
DR   A0L1R0, LEU1_SHESA ;  A8FQ83, LEU1_SHESH ;  Q0HE65, LEU1_SHESM ;
DR   Q0HZT4, LEU1_SHESR ;  A1REY0, LEU1_SHESW ;  B1KKZ4, LEU1_SHEWM ;
DR   B2U281, LEU1_SHIB3 ;  Q326G1, LEU1_SHIBS ;  Q32K20, LEU1_SHIDS ;
DR   Q0T8C4, LEU1_SHIF8 ;  Q83SP0, LEU1_SHIFL ;  Q3Z5T6, LEU1_SHISS ;
DR   Q2NVW3, LEU1_SODGM ;  Q39891, LEU1_SOYBN ;  E1R5X1, LEU1_SPISS ;
DR   A7X4N1, LEU1_STAA1 ;  A6U3E2, LEU1_STAA2 ;  Q2FF67, LEU1_STAA3 ;
DR   Q2FWK3, LEU1_STAA8 ;  A5IUK3, LEU1_STAA9 ;  Q2YUF2, LEU1_STAAB ;
DR   Q5HEE4, LEU1_STAAC ;  A6QIQ3, LEU1_STAAE ;  P63476, LEU1_STAAM ;
DR   P63477, LEU1_STAAN ;  Q6GF16, LEU1_STAAR ;  Q6G7Q1, LEU1_STAAS ;
DR   A8Z4W0, LEU1_STAAT ;  P58899, LEU1_STAAW ;  B9DMJ6, LEU1_STACT ;
DR   Q5HMF9, LEU1_STAEQ ;  Q8CNL3, LEU1_STAES ;  Q4L7U0, LEU1_STAHJ ;
DR   Q49Z12, LEU1_STAS1 ;  Q82BV3, LEU1_STRAW ;  O31046, LEU1_STRCO ;
DR   D3HCJ2, LEU1_STRG3 ;  B4SI67, LEU1_STRM5 ;  B2FT78, LEU1_STRMK ;
DR   D2ATJ4, LEU1_STRRD ;  Q97W36, LEU1_SULSO ;  Q974X3, LEU1_SULTO ;
DR   Q2LWJ3, LEU1_SYNAS ;  B1XLQ9, LEU1_SYNP2 ;  A5GM47, LEU1_SYNPW ;
DR   Q7U892, LEU1_SYNPX ;  A5GRZ0, LEU1_SYNR3 ;  Q0IBI3, LEU1_SYNS3 ;
DR   Q3AYY2, LEU1_SYNS9 ;  Q3AIA2, LEU1_SYNSC ;  P48576, LEU1_SYNY3 ;
DR   Q8DJ32, LEU1_THEEB ;  Q47RM9, LEU1_THEFY ;  Q9WZ23, LEU1_THEMA ;
DR   B9KB95, LEU1_THENN ;  A5IJM2, LEU1_THEP1 ;  B1L8U2, LEU1_THESQ ;
DR   Q56216, LEU1_THETH ;  Q3SHE7, LEU1_THIDA ;  C4LAV7, LEU1_TOLAT ;
DR   Q112U2, LEU1_TRIEI ;  B1H0A7, LEU1_UNCTG ;  C5CYP2, LEU1_VARPS ;
DR   A1WNY5, LEU1_VEREI ;  A5CWZ3, LEU1_VESOH ;  Q9KP83, LEU1_VIBCH ;
DR   C3LR32, LEU1_VIBCM ;  Q5E856, LEU1_VIBF1 ;  B5FGH4, LEU1_VIBFM ;
DR   Q87SS7, LEU1_VIBPA ;  B7VIF2, LEU1_VIBSL ;  Q8DEE1, LEU1_VIBVU ;
DR   Q7MP77, LEU1_VIBVY ;  Q7M9W4, LEU1_WOLSU ;  P58900, LEU1_XANAC ;
DR   Q3BPJ9, LEU1_XANC5 ;  Q4UYG1, LEU1_XANC8 ;  B0RP28, LEU1_XANCB ;
DR   P58901, LEU1_XANCP ;  Q2P761, LEU1_XANOM ;  B2SNG9, LEU1_XANOP ;
DR   Q5H4C6, LEU1_XANOR ;  B2I596, LEU1_XYLF2 ;  Q9PCG3, LEU1_XYLFA ;
DR   Q87CL8, LEU1_XYLFT ;  P06208, LEU1_YEAST ;  A1JJH7, LEU1_YERE8 ;
DR   A7FM84, LEU1_YERP3 ;  Q1C1Z6, LEU1_YERPA ;  B2K4C9, LEU1_YERPB ;
DR   Q8ZIG8, LEU1_YERPE ;  A9R142, LEU1_YERPG ;  Q1CMP5, LEU1_YERPN ;
DR   A4TQA2, LEU1_YERPP ;  Q66EM1, LEU1_YERPS ;  B1JK98, LEU1_YERPY ;
DR   Q12166, LEU9_YEAST ;
//
ID   2.3.3.14
DE   Homocitrate synthase.
AN   2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA-
AN   acetylating).
AN   Acetyl-coenzyme A:2-ketoglutarate C-acetyl transferase.
AN   Homocitrate synthetase.
CA   Acetyl-CoA + H(2)O + 2-oxoglutarate = (R)-2-hydroxybutane-1,2,4-
CA   tricarboxylate + CoA.
CC   -!- Belongs in the alpha-aminoadipate pathway of lysine synthesis, along
CC       with EC 4.2.1.36.
CC   -!- Also acts with oxaloacetate as substrate, but more slowly.
CC   -!- Formerly EC 4.1.3.21.
PR   PROSITE; PDOC00643;
PR   PROSITE; PDOC50991;
DR   Q8TKQ6, AKSA_METAC ;  Q57926, AKSA_METJA ;  Q8TW28, AKSA_METKA ;
DR   P58967, AKSA_METMA ;  O27667, AKSA_METTH ;  Q9V1J1, HOSA_PYRAB ;
DR   O59390, HOSA_PYRHO ;  C3N5A3, HOSA_SULIA ;  C4KGW9, HOSA_SULIK ;
DR   C3MPM7, HOSA_SULIL ;  C3MYM1, HOSA_SULIM ;  C3NHU6, HOSA_SULIN ;
DR   C3NDV7, HOSA_SULIY ;  Q97ZE0, HOSA_SULSO ;  Q971S5, HOSA_SULTO ;
DR   O87198, HOSC_THET2 ;  P48570, HOSC_YEAST ;  O94225, HOSM_PENCW ;
DR   Q9Y823, HOSM_SCHPO ;  Q12726, HOSM_YARLI ;  Q12122, HOSM_YEAST ;
DR   Q44290, NIFV1_NOSS1;  P58637, NIFV2_NOSS1;  Q00853, NIFVA_CLOPA;
DR   Q00852, NIFVO_CLOPA;  P70728, NIFV_AZOBR ;  P23122, NIFV_AZOCH ;
DR   P05342, NIFV_AZOVI ;  Q52070, NIFV_ENTAG ;  Q47884, NIFV_FRAAL ;
DR   P54610, NIFV_FRASP ;  P05345, NIFV_KLEPN ;  Q07179, NIFV_RHOCA ;
DR   Q01181, NIFV_RHOSH ;
//
ID   2.3.3.15
DE   Sulfoacetaldehyde acetyltransferase.
CA   Acetyl phosphate + sulfite = 2-sulfoacetaldehyde + phosphate.
CF   Magnesium; Thiamine diphosphate.
CC   -!- The reaction occurs in the reverse direction to that shown above.
PR   PROSITE; PDOC00166;
DR   Q84H44, XSC_ALCDF  ;  Q84H41, XSC_ALCXX  ;  Q93PS3, XSC_DESTI  ;
DR   Q92UW6, XSC_RHIME  ;
//
ID   2.4.1.1
DE   Phosphorylase.
AN   Amylophosphorylase.
AN   Muscle phosphorylase a and b.
AN   Polyphosphorylase.
CA   (1,4-alpha-D-glucosyl)(n) + phosphate = (1,4-alpha-D-glucosyl)(n-1) +
CA   alpha-D-glucose 1-phosphate.
CC   -!- The description (official name) should be qualified in each instance
CC       by adding the name of the natural substance, e.g. maltodextrin
CC       phosphorylase, starch phosphorylase, glycogen phosphorylase.
PR   PROSITE; PDOC00095;
DR   Q00766, PHS1_DICDI ;  P34114, PHS2_DICDI ;  O66932, PHSG_AQUAE ;
DR   P39123, PHSG_BACSU ;  Q9PKE6, PHSG_CHLMU ;  Q9Z8N1, PHSG_CHLPN ;
DR   O84250, PHSG_CHLTR ;  P0AC86, PHSG_ECOLI ;  P45180, PHSG_HAEIN ;
DR   Q7U078, PHSG_MYCBO ;  Q10639, PHSG_MYCTU ;  Q9CN90, PHSG_PASMU ;
DR   P0AC87, PHSG_SHIFL ;  P73511, PHSG_SYNY3 ;  P06738, PHSG_YEAST ;
DR   Q9SD76, PHSH_ARATH ;  P32811, PHSH_SOLTU ;  P53537, PHSH_VICFA ;
DR   Q9LKJ3, PHSH_WHEAT ;  P04045, PHSL1_SOLTU;  P53535, PHSL2_SOLTU;
DR   P27598, PHSL_IPOBA ;  P53536, PHSL_VICFA ;  P00490, PHSM_ECOLI ;
DR   P07094, PHSM_KLEPN ;  P29849, PHSM_STRPN ;  Q3B7M9, PYGB_BOVIN ;
DR   P11216, PYGB_HUMAN ;  Q8CI94, PYGB_MOUSE ;  Q5R5M6, PYGB_PONAB ;
DR   P53534, PYGB_RAT   ;  Q5MIB6, PYGB_SHEEP ;  Q0VCM4, PYGL_BOVIN ;
DR   P06737, PYGL_HUMAN ;  Q9ET01, PYGL_MOUSE ;  P09811, PYGL_RAT   ;
DR   Q5MIB5, PYGL_SHEEP ;  P79334, PYGM_BOVIN ;  P11217, PYGM_HUMAN ;
DR   Q8HXW4, PYGM_MACFA ;  Q9WUB3, PYGM_MOUSE ;  P00489, PYGM_RABIT ;
DR   P09812, PYGM_RAT   ;  O18751, PYGM_SHEEP ;  Q9XTL9, PYG_DROME  ;
//
ID   2.4.1.2
DE   Dextrin dextranase.
AN   Dextrin 6-glucosyltransferase.
CA   ((1->4)-alpha-D-glucosyl)(n) + ((1->6)-alpha-D-glucosyl)(m) = ((1->4)-
CA   alpha-D-glucosyl)(n-1) + ((1->6)-alpha-D-glucosyl)(m+1).
//
ID   2.4.1.3
DE   Transferred entry: 2.4.1.25.
//
ID   2.4.1.4
DE   Amylosucrase.
AN   Sucrose--glucan glucosyltransferase.
CA   Sucrose + ((1->4)-alpha-D-glucosyl)(n) = D-fructose + ((1->4)-alpha-D-
CA   glucosyl)(n+1).
DR   Q84HD6, AMYS_NEIME ;  Q9ZEU2, AMYS_NEIPO ;
//
ID   2.4.1.5
DE   Dextransucrase.
AN   Sucrose 6-glucosyltransferase.
CA   Sucrose + ((1->6)-alpha-D-glucosyl)(n) = D-fructose + ((1->6)-alpha-D-
CA   glucosyl)(n+1).
DR   B2MUU6, GTF1_LEUME ;  P11001, GTF1_STRDO ;  P85089, GTF2_LEUME ;
DR   P27470, GTF2_STRDO ;  P85080, GTF3_LEUME ;  P86897, GTF4_LEUME ;
DR   P08987, GTFB_STRMU ;  P13470, GTFC_STRMU ;  P49331, GTFD_STRMU ;
DR   P29336, GTFS_STRDO ;
//
ID   2.4.1.6
DE   Deleted entry.
//
ID   2.4.1.7
DE   Sucrose phosphorylase.
AN   Disaccharide glucosyltransferase.
AN   Sucrose glucosyltransferase.
CA   Sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate.
CC   -!- In the forward reaction, arsenate may replace phosphate.
CC   -!- In the reverse reaction, various ketoses and L-arabinose may replace
CC       D-fructose.
DR   P33910, SUCP_AGRVI ;  P76041, SUCP_ECOLI ;  Q59495, SUCP_LEUME ;
DR   P10249, SUCP_STRMU ;
//
ID   2.4.1.8
DE   Maltose phosphorylase.
CA   Maltose + phosphate = D-glucose + beta-D-glucose 1-phosphate.
//
ID   2.4.1.9
DE   Inulosucrase.
AN   Sucrose 1-fructosyltransferase.
CA   Sucrose + ((2->1)-beta-D-fructosyl)(n) = glucose + ((2->1)-beta-D-
CA   fructosyl)(n+1).
CC   -!- Converts sucrose into inulin and D-glucose.
CC   -!- Some other sugars can act as D-fructosyl acceptors.
//
ID   2.4.1.10
DE   Levansucrase.
AN   Sucrose 6-fructosyltransferase.
CA   Sucrose + (6)-beta-D-fructofuranosyl-(2->)(n) alpha-D-glucopyranoside =
CA   glucose + (6)-beta-D-fructofuranosyl-(2->)(n+1) alpha-D-glucopyranoside.
CC   -!- Some other sugars can act as D-fructosyl acceptors.
DR   P21130, SACB_BACAM ;  P05655, SACB_BACSU ;  Q46654, SACB_ERWAM ;
DR   Q43998, SACB_GLUDI ;  O52408, SACB_PSESG ;  O68609, SACB_PSESH ;
DR   O54435, SACB_RAHAQ ;  P11701, SACB_STRMU ;  Q55242, SACB_STRSL ;
DR   Q60114, SACB_ZYMMO ;
//
ID   2.4.1.11
DE   Glycogen(starch) synthase.
AN   UDP-glucose--glycogen glucosyltransferase.
CA   UDP-glucose ((1->4)-alpha-D-glucosyl)(n) = UDP + ((1->4)-alpha-D-
CA   glucosyl)(n+1).
CC   -!- The description (official name) varies according to the source of the
CC       enzyme and the nature of its synthetic product.
CC   -!- Glycogen synthase from animal tissues is a complex of a catalytic
CC       subunit and the protein glycogenin.
CC   -!- The enzyme requires glucosylated glycogenin as a primer; this is the
CC       reaction product of EC 2.4.1.186.
CC   -!- A similar enzyme utilizes ADP-glucose (cf. EC 2.4.1.21).
DR   A7MB78, GYS1_BOVIN ;  P13807, GYS1_HUMAN ;  Q8MJ26, GYS1_MACMU ;
DR   Q9Z1E4, GYS1_MOUSE ;  Q5R9H0, GYS1_PONAB ;  P13834, GYS1_RABIT ;
DR   A2RRU1, GYS1_RAT   ;  P23337, GYS1_YEAST ;  P54840, GYS2_HUMAN ;
DR   Q8VCB3, GYS2_MOUSE ;  P17625, GYS2_RAT   ;  P27472, GYS2_YEAST ;
DR   Q9U2D9, GYS_CAEEL  ;  Q55GH4, GYS_DICDI  ;  Q9VFC8, GYS_DROME  ;
DR   O93869, GYS_NEUCR  ;
//
ID   2.4.1.12
DE   Cellulose synthase (UDP-forming).
AN   UDP-glucose--beta-glucan glucosyltransferase.
AN   UDP-glucose-beta-D-glucan glucosyltransferase.
AN   UDP-glucose-cellulose glucosyltransferase.
CA   UDP-glucose + (1,4-beta-D-glucosyl)(n) = UDP + (1,4-beta-D-
CA   glucosyl)(n+1).
CC   -!- Involved in the synthesis of cellulose.
CC   -!- A similar enzyme utilizes GDP-glucose (cf. EC 2.4.1.29).
DR   Q76KJ8, ACSA1_GLUHA;  P0CW87, ACSA1_GLUXY;  Q59167, ACSA2_GLUHA;
DR   P19449, BCSA1_GLUXY;  O82859, BCSA2_GLUXY;  Q9WX61, BCSA3_GLUXY;
DR   Q9RBJ2, BCSA4_GLUXY;  Q9WX75, BCSA5_GLUXY;  Q8X5L7, BCSA_ECO57 ;
DR   P37653, BCSA_ECOLI ;  P58931, BCSA_PSEFS ;  Q8Z291, BCSA_SALTI ;
DR   Q93IN2, BCSA_SALTY ;  P58932, BCSA_XANAC ;  O48946, CESA1_ARATH;
DR   A2Y0X2, CESA1_ORYSI;  Q6AT26, CESA1_ORYSJ;  O48947, CESA2_ARATH;
DR   A2XN66, CESA2_ORYSI;  Q84M43, CESA2_ORYSJ;  Q941L0, CESA3_ARATH;
DR   Q69V23, CESA3_ORYSJ;  Q84JA6, CESA4_ARATH;  A2WV32, CESA4_ORYSI;
DR   Q5JN63, CESA4_ORYSJ;  Q8L778, CESA5_ARATH;  A2XNT2, CESA5_ORYSI;
DR   Q851L8, CESA5_ORYSJ;  Q94JQ6, CESA6_ARATH;  Q6YVM4, CESA6_ORYSJ;
DR   Q9SWW6, CESA7_ARATH;  Q9AV71, CESA7_ORYSJ;  Q8LPK5, CESA8_ARATH;
DR   Q84ZN6, CESA8_ORYSJ;  Q9SJ22, CESA9_ARATH;  A2Z1C8, CESA9_ORYSI;
DR   Q69P51, CESA9_ORYSJ;  Q9SKJ5, CESAA_ARATH;  Q69XK5, CESAB_ORYSJ;
DR   Q9U720, DCSA_DICDI ;
//
ID   2.4.1.13
DE   Sucrose synthase.
AN   Sucrose synthetase.
AN   Sucrose-UDP glucosyltransferase.
AN   Sucrose-uridine diphosphate glucosyltransferase.
AN   UDP-glucose-fructose glucosyltransferase.
AN   Uridine diphosphoglucose-fructose glucosyltransferase.
CA   NDP-glucose + D-fructose = NDP + sucrose.
CC   -!- Although UDP is generally considered to be the preferred nucleoside
CC       diphosphate for sucrose synthase, numerous studies have shown that
CC       ADP serves as an effective acceptor molecule to produce ADP-glucose.
CC   -!- Sucrose synthase has a dual role in producing both UDP-glucose
CC       (necessary for cell wall and glycoprotein biosynthesis) and ADP-
CC       glucose (necessary for starch biosynthesis).
DR   P49040, SUS1_ARATH ;  P49035, SUS1_DAUCA ;  P31922, SUS1_HORVU ;
DR   P04712, SUS1_MAIZE ;  P31924, SUS1_ORYSJ ;  P10691, SUS1_SOLTU ;
DR   Q41608, SUS1_TULGE ;  Q00917, SUS2_ARATH ;  O49845, SUS2_DAUCA ;
DR   P31923, SUS2_HORVU ;  P49036, SUS2_MAIZE ;  P30298, SUS2_ORYSJ ;
DR   O24301, SUS2_PEA   ;  P49039, SUS2_SOLTU ;  Q41607, SUS2_TULGE ;
DR   Q43009, SUS3_ORYSJ ;  P49034, SUSY_ALNGL ;  Q42652, SUSY_BETVU ;
DR   O65026, SUSY_MEDSA ;  P31925, SUSY_SACOF ;  P49037, SUSY_SOLLC ;
DR   P13708, SUSY_SOYBN ;  P31926, SUSY_VICFA ;  Q01390, SUSY_VIGRR ;
//
ID   2.4.1.14
DE   Sucrose-phosphate synthase.
AN   Sucrosephosphate--UDP glucosyltransferase.
AN   UDP-glucose-fructose-phosphate glucosyltransferase.
CA   UDP-glucose + D-fructose 6-phosphate = UDP + sucrose 6(F)-phosphate.
CF   Manganese or magnesium.
CC   -!- The enzyme from Synechocystis sp. strain PCC 6803 is not specific for
CC       UDP-glucose as it can use ADP-glucose and, to a lesser extent, GDP-
CC       glucose as substrates.
CC   -!- The enzyme from rice leaves is activated by glucose 6-phosphate but
CC       that from cyanobacterial species is not.
CC   -!- While the reaction catalyzed by this enzyme is reversible, the enzyme
CC       usually works in concert with EC 3.1.3.24 to form sucrose, making the
CC       above reaction essentially irreversible.
CC   -!- The F in sucrose 6(F)-phosphate is used to indicate that the fructose
CC       residue of sucrose carries the substituent.
DR   O22060, SPS1_CITUN ;  O04932, SPS1_CRAPL ;  O04933, SPS2_CRAPL ;
DR   P49031, SPS_BETVU  ;  P31927, SPS_MAIZE  ;  A2WYE9, SPS_ORYSI  ;
DR   Q0JGK4, SPS_ORYSJ  ;  Q43845, SPS_SOLTU  ;  P31928, SPS_SPIOL  ;
DR   Q43876, SPS_VICFA  ;
//
ID   2.4.1.15
DE   Alpha,alpha-trehalose-phosphate synthase (UDP-forming).
AN   Transglucosylase.
AN   Trehalose 6-phosphate synthase.
AN   Trehalose 6-phosphate synthetase.
AN   Trehalose phosphate synthase.
AN   Trehalose phosphate synthetase.
AN   Trehalosephosphate-UDP glucosyltransferase.
AN   UDP-glucose--glucose-phosphate glucosyltransferase.
CA   UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose
CA   6-phosphate.
CC   -!- See also EC 2.4.1.36.
DR   A8AFD4, OTSA_CITK8 ;  A7ZN22, OTSA_ECO24 ;  Q8XCE7, OTSA_ECO57 ;
DR   B1X658, OTSA_ECODH ;  A8A1A0, OTSA_ECOHS ;  A1AC53, OTSA_ECOK1 ;
DR   Q0TGU0, OTSA_ECOL5 ;  Q8FGN6, OTSA_ECOL6 ;  B1J0J4, OTSA_ECOLC ;
DR   P31677, OTSA_ECOLI ;  B1LQW0, OTSA_ECOSM ;  Q1RAP1, OTSA_ECOUT ;
DR   A4WBR1, OTSA_ENT38 ;  A7MEE9, OTSA_ENTS8 ;  A6TB47, OTSA_KLEP7 ;
DR   Q6JTB2, OTSA_PSESS ;  P55612, OTSA_RHISN ;  A9MMQ2, OTSA_SALAR ;
DR   Q57N70, OTSA_SALCH ;  Q5PMW8, OTSA_SALPA ;  A9MU86, OTSA_SALPB ;
DR   P0A1Q1, OTSA_SALTI ;  E1WGG8, OTSA_SALTS ;  P0CL06, OTSA_SALTY ;
DR   Q32H58, OTSA_SHIDS ;  Q3Z2S4, OTSA_SHISS ;  Q2NTK9, OTSA_SODGM ;
DR   O80738, TPS10_ARATH;  Q9ZV48, TPS11_ARATH;  Q5K2C4, TPS1_APHAV ;
DR   Q9SYM4, TPS1_ARATH ;  A8WRG3, TPS1_CAEBR ;  Q7YZT6, TPS1_CAEEL ;
DR   Q92410, TPS1_CANAL ;  O59921, TPS1_EMENI ;  Q8SSL2, TPS1_ENCCU ;
DR   Q07158, TPS1_KLULA ;  O94213, TPS1_PICAN ;  P40387, TPS1_SCHPO ;
DR   O74932, TPS1_YARLI ;  Q00764, TPS1_YEAST ;  Q96WK6, TPS1_ZYGRO ;
DR   Q5K2C1, TPS2_APHAV ;  Q9FZ57, TPS2_ARATH ;  O45380, TPS2_CAEEL ;
DR   Q9SHG0, TPS3_ARATH ;  Q9T079, TPS4_ARATH ;  O23617, TPS5_ARATH ;
DR   Q94AH8, TPS6_ARATH ;  Q9LMI0, TPS7_ARATH ;  Q0WUI9, TPS8_ARATH ;
DR   Q9LRA7, TPS9_ARATH ;  Q00075, TPSA_ASPNG ;  Q54K57, TPSA_DICDI ;
DR   Q00217, TPSB_ASPNG ;  Q54NU9, TPSB_DICDI ;  O14081, TPSX_SCHPO ;
DR   Q9UUI7, TPSY_SCHPO ;
//
ID   2.4.1.16
DE   Chitin synthase.
AN   Chitin-UDP acetyl-glucosaminyl transferase.
CA   UDP-N-acetyl-D-glucosamine + (1,4-(N-acetyl-beta-D-glucosaminyl))(n) =
CA   UDP + (1,4-(N-acetyl-beta-D-glucosaminyl))(n+1).
CC   -!- Converts UDP-N-acetyl-D-glucosamine into chitin and UDP.
DR   P30576, CHS1_AJECA ;  P30579, CHS1_AJEDE ;  P30581, CHS1_ASPNG ;
DR   P49603, CHS1_BOTFU ;  P23316, CHS1_CANAL ;  O13356, CHS1_CRYNV ;
DR   Q8SSI7, CHS1_ENCCU ;  P30600, CHS1_EXODE ;  P30585, CHS1_EXOJE ;
DR   P29070, CHS1_NEUCR ;  P30590, CHS1_PHAEX ;  P87073, CHS1_PHYBL ;
DR   P30592, CHS1_RHIAT ;  P30594, CHS1_RHIOL ;  Q12632, CHS1_RHIRA ;
DR   P30596, CHS1_SCHCO ;  P30597, CHS1_SCHPO ;  P55003, CHS1_TUBUN ;
DR   P30598, CHS1_USTMA ;  P30603, CHS1_XYLBA ;  P08004, CHS1_YEAST ;
DR   P30577, CHS2_AJECA ;  P30580, CHS2_AJEDE ;  P30582, CHS2_ASPNG ;
DR   P30572, CHS2_CANAL ;  P30601, CHS2_EXODE ;  P30586, CHS2_EXOJE ;
DR   P30589, CHS2_NEUCR ;  Q92444, CHS2_PARBR ;  P30591, CHS2_PHAEX ;
DR   P30593, CHS2_RHIAT ;  P30595, CHS2_RHIOL ;  P30599, CHS2_USTMA ;
DR   P30604, CHS2_XYLBA ;  P14180, CHS2_YEAST ;  P30578, CHS3_AJECA ;
DR   P30573, CHS3_CANAL ;  P30602, CHS3_EXODE ;  P30587, CHS3_EXOJE ;
DR   P30588, CHS3_NEUCR ;  Q99126, CHS3_USTMA ;  P29465, CHS3_YEAST ;
DR   O13353, CHS4_MAGO7 ;  Q01285, CHS4_NEUCR ;  Q99127, CHS4_USTMA ;
DR   O13394, CHS5_USTMA ;  O13395, CHS6_USTMA ;  Q4P333, CHS7_USTMA ;
DR   Q4P9K9, CHS8_USTMA ;  Q12564, CHSA_AMPQU ;  P30584, CHSA_EMENI ;
DR   Q00757, CHSB_EMENI ;  Q92197, CHSC_ASPFU ;  P30583, CHSC_EMENI ;
DR   P78746, CHSD_ASPFU ;  P78611, CHSD_EMENI ;  P54267, CHSG_ASPFU ;
DR   P48017, CHS_SAPMO  ;
//
ID   2.4.1.17
DE   Glucuronosyltransferase.
AN   1-naphthol glucuronyltransferase.
AN   1-naphthol-UDP-glucuronosyltransferase.
AN   17-beta-hydroxysteroid UDP-glucuronosyltransferase.
AN   17-OH steroid UDPGT.
AN   3-alpha-hydroxysteroid UDP-glucuronosyltransferase.
AN   3-OH androgenic UDPGT.
AN   4-hydroxybiphenyl UDP-glucuronosyltransferase.
AN   4-methylumbelliferone UDP-glucuronosyltransferase.
AN   4-nitrophenol UDP-glucuronyltransferase.
AN   4-nitrophenol UDPGT.
AN   Bilirubin glucuronyltransferase.
AN   Bilirubin monoglucuronide glucuronyltransferase.
AN   Bilirubin UDP-glucuronosyltransferase.
AN   Bilirubin UDPGT.
AN   Bilirubin uridine diphosphoglucuronyltransferase.
AN   Ciramadol UDP-glucuronyltransferase.
AN   Estriol UDPglucuronosyltransferase.
AN   Estrone UDPglucuronosyltransferase.
AN   GT.
AN   Morphine glucuronyltransferase.
AN   p-hydroxybiphenyl UDP glucuronyltransferase.
AN   p-nitrophenol UDP-glucuronosyltransferase.
AN   p-nitrophenol UDP-glucuronyltransferase.
AN   p-nitrophenylglucuronosyltransferase.
AN   p-phenylphenol glucuronyltransferase.
AN   Phenyl-UDP-glucuronosyltransferase.
AN   PNP-UDPGT.
AN   UDP glucuronate-estradiol-glucuronosyltransferase.
AN   UDP glucuronate-estriol glucuronosyltransferase.
AN   UDP glucuronic acid transferase.
AN   UDP glucuronyltransferase.
AN   UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase.
AN   UDP-glucuronate-bilirubin glucuronyltransferase.
AN   UDP-glucuronosyltransferase.
AN   UDP-glucuronyltransferase.
AN   UDPGA transferase.
AN   UDPGA-glucuronyltransferase.
AN   UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific).
AN   UDPGT.
AN   Uridine 5'-diphosphoglucuronyltransferase.
AN   Uridine diphosphate glucuronyltransferase.
AN   Uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase.
AN   Uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase.
AN   Uridine diphosphoglucuronate-bilirubin glucuronoside
AN   glucuronosyltransferase.
AN   Uridine diphosphoglucuronate-bilirubin glucuronosyltransferase.
AN   Uridine diphosphoglucuronate-estradiol glucuronosyltransferase.
AN   Uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase.
AN   Uridine diphosphoglucuronate-estriol glucuronosyltransferase.
AN   Uridine diphosphoglucuronosyltransferase.
AN   Uridine diphosphoglucuronyltransferase.
CA   UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.
CC   -!- Family of enzymes accepting a wide range of substrates, including
CC       phenols, alcohols, amines and fatty acids.
CC   -!- Some of the activities catalyzed were previously listed separately as
CC       EC 2.4.1.42, EC 2.4.1.59, EC 2.4.1.61, EC 2.4.1.76, EC 2.4.1.77,
CC       EC 2.4.1.84, EC 2.4.1.107 and EC 2.4.1.108.
CC   -!- A temporary nomenclature for the various forms whose delineation is
CC       in a state of flux.
PR   PROSITE; PDOC00359;
DR   Q9HAW8, UD110_HUMAN;  P22309, UD11_HUMAN ;  Q63886, UD11_MOUSE ;
DR   Q64550, UD11_RAT   ;  P70691, UD12_MOUSE ;  P20720, UD12_RAT   ;
DR   P35503, UD13_HUMAN ;  Q64637, UD13_RAT   ;  P22310, UD14_HUMAN ;
DR   Q28612, UD14_RABIT ;  P35504, UD15_HUMAN ;  Q64638, UD15_RAT   ;
DR   P19224, UD16_HUMAN ;  Q64435, UD16_MOUSE ;  Q28611, UD16_RABIT ;
DR   P08430, UD16_RAT   ;  Q6ZQM8, UD17C_MOUSE;  Q9HAW7, UD17_HUMAN ;
DR   Q64633, UD17_RAT   ;  Q9HAW9, UD18_HUMAN ;  Q64634, UD18_RAT   ;
DR   O60656, UD19_HUMAN ;  Q62452, UD19_MOUSE ;  Q9Y4X1, UD2A1_HUMAN;
DR   Q80X89, UD2A1_MOUSE;  P36510, UD2A1_RAT  ;  Q6PDD0, UD2A2_MOUSE;
DR   Q9R110, UD2A3_CAVPO;  Q6UWM9, UD2A3_HUMAN;  Q8BWQ1, UD2A3_MOUSE;
DR   Q5RFJ3, UD2A3_PONAB;  P09875, UD2B1_RAT  ;  P08541, UD2B2_RAT  ;
DR   P06133, UD2B4_HUMAN;  P16662, UD2B7_HUMAN;  Q62789, UD2B7_RAT  ;
DR   O02663, UD2B9_MACFA;  P36514, UD2C1_RABIT;  Q1LZI1, UD3A1_BOVIN;
DR   Q6NUS8, UD3A1_HUMAN;  Q3UP75, UD3A1_MOUSE;  Q63ZR6, UD3A1_XENLA;
DR   Q3SY77, UD3A2_HUMAN;  Q8JZZ0, UD3A2_MOUSE;  P36537, UDB10_HUMAN;
DR   O75310, UDB11_HUMAN;  P36512, UDB13_RABIT;  P36513, UDB14_RABIT;
DR   P54855, UDB15_HUMAN;  P36511, UDB15_RAT  ;  O19103, UDB16_RABIT;
DR   O75795, UDB17_HUMAN;  P17717, UDB17_MOUSE;  P08542, UDB17_RAT  ;
DR   O97951, UDB18_MACFA;  Q9XT55, UDB19_MACFA;  O77649, UDB20_MACFA;
DR   Q9TSL6, UDB23_MACFA;  Q9BY64, UDB28_HUMAN;  Q8WN97, UDB30_MACFA;
DR   Q6K1J1, UDB31_CANFA;  Q9GLD9, UDB33_MACMU;  P19488, UDB37_RAT  ;
DR   Q91280, UGT3_PLEPL ;  Q10941, UGT46_CAEEL;  A8WLF6, UGT47_CAEBR;
DR   Q21706, UGT47_CAEEL;  Q18081, UGT48_CAEEL;  Q22295, UGT50_CAEEL;
DR   Q22180, UGT55_CAEEL;  Q22181, UGT56_CAEEL;  Q20086, UGT58_CAEEL;
DR   P34317, UGT60_CAEEL;
//
ID   2.4.1.18
DE   1,4-alpha-glucan branching enzyme.
AN   Amylo-(1,4 to 1,6)transglucosidase.
AN   Amylo-(1,4->1,6)-transglycosylase.
AN   Branching enzyme.
AN   Glycogen branching enzyme.
CA   Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy
CA   group in a similar glucan chain.
CC   -!- Converts amylose into amylopectin.
CC   -!- The description (official name) requires a qualification depending on
CC       the product, glycogen or amylopectin, e.g. glycogen branching enzyme,
CC       amylopectin branching enzyme.
CC   -!- The latter has frequently been termed Q-enzyme.
DR   Q8XPA2, GLGB1_CLOPE;  Q0SWZ1, GLGB1_CLOPS;  Q2K487, GLGB1_RHIEC;
DR   Q1MBS9, GLGB1_RHIL3;  Q82JF0, GLGB1_STRAW;  Q59833, GLGB1_STRCO;
DR   Q8PR13, GLGB1_XANAC;  Q3BZE1, GLGB1_XANC5;  Q4V0E2, GLGB1_XANC8;
DR   Q8PE48, GLGB1_XANCP;  Q2P9F7, GLGB1_XANOM;  Q5H6H2, GLGB1_XANOR;
DR   Q8XK15, GLGB2_CLOPE;  Q0SSN2, GLGB2_CLOPS;  Q2JZ21, GLGB2_RHIEC;
DR   Q1M3A7, GLGB2_RHIL3;  Q825Q8, GLGB2_STRAW;  Q59832, GLGB2_STRCO;
DR   Q8PQA2, GLGB2_XANAC;  Q3BYI0, GLGB2_XANC5;  Q4UZL7, GLGB2_XANC8;
DR   Q8PDD1, GLGB2_XANCP;  Q2P949, GLGB2_XANOM;  Q5H6Q3, GLGB2_XANOR;
DR   A3MZ64, GLGB_ACTP2 ;  B3H0J1, GLGB_ACTP7 ;  B0BT96, GLGB_ACTPJ ;
DR   A6VP15, GLGB_ACTSZ ;  Q8U8L4, GLGB_AGRT5 ;  Q0AA26, GLGB_ALHEH ;
DR   Q3M473, GLGB_ANAVT ;  O66936, GLGB_AQUAE ;  Q5NXV7, GLGB_AROAE ;
DR   Q757Q6, GLGB_ASHGO ;  Q96VA4, GLGB_ASPOR ;  C3PCL8, GLGB_BACAA ;
DR   C3LC26, GLGB_BACAC ;  Q81K82, GLGB_BACAN ;  B7JDF1, GLGB_BACC0 ;
DR   Q72YJ3, GLGB_BACC1 ;  B7IM37, GLGB_BACC2 ;  C1EX54, GLGB_BACC3 ;
DR   B7HBC7, GLGB_BACC4 ;  B7HTX9, GLGB_BACC7 ;  P30537, GLGB_BACCL ;
DR   A7GUA1, GLGB_BACCN ;  B9J2G8, GLGB_BACCQ ;  Q816G6, GLGB_BACCR ;
DR   Q632H1, GLGB_BACCZ ;  Q6HC15, GLGB_BACHK ;  Q65FS4, GLGB_BACLD ;
DR   P39118, GLGB_BACSU ;  A9VMV8, GLGB_BACWK ;  Q8G5L0, GLGB_BIFLO ;
DR   Q7WII7, GLGB_BORBR ;  Q7W6L4, GLGB_BORPA ;  Q7VYK0, GLGB_BORPE ;
DR   Q89FD3, GLGB_BRAJA ;  A5EPZ7, GLGB_BRASB ;  A4Z005, GLGB_BRASO ;
DR   Q1BVW7, GLGB_BURCA ;  A0KDG4, GLGB_BURCH ;  Q0B3Y4, GLGB_BURCM ;
DR   A3NU16, GLGB_BURP0 ;  Q3JTG5, GLGB_BURP1 ;  A3N8B3, GLGB_BURP6 ;
DR   Q63T91, GLGB_BURPS ;  Q39N89, GLGB_BURS3 ;  Q2T6R3, GLGB_BURTA ;
DR   A4JR39, GLGB_BURVG ;  Q13S07, GLGB_BURXL ;  P30539, GLGB_BUTFI ;
DR   Q6FJV0, GLGB_CANGA ;  B3PGN4, GLGB_CELJU ;  Q5L6K4, GLGB_CHLAB ;
DR   Q823Y5, GLGB_CHLCV ;  Q253M6, GLGB_CHLFF ;  Q9PL51, GLGB_CHLMU ;
DR   Q9Z876, GLGB_CHLPN ;  B0B998, GLGB_CHLT2 ;  Q3KKH0, GLGB_CHLTA ;
DR   B0BAX7, GLGB_CHLTB ;  O84874, GLGB_CHLTR ;  A8AQY3, GLGB_CITK8 ;
DR   Q0TQ16, GLGB_CLOP1 ;  Q6NHR6, GLGB_CORDI ;  Q8FQ12, GLGB_COREF ;
DR   Q8NR40, GLGB_CORGL ;  Q4JUK5, GLGB_CORJK ;  P0CN83, GLGB_CRYNB ;
DR   P0CN82, GLGB_CRYNJ ;  Q0K0X8, GLGB_CUPNH ;  Q46TF2, GLGB_CUPPJ ;
DR   Q6BXN1, GLGB_DEBHA ;  Q47II8, GLGB_DECAR ;  Q1IZQ3, GLGB_DEIGD ;
DR   Q9RTB7, GLGB_DEIRA ;  Q30Z14, GLGB_DESDG ;  Q24VW3, GLGB_DESHY ;
DR   Q729V5, GLGB_DESVH ;  A1VC54, GLGB_DESVV ;  Q555Q9, GLGB_DICDI ;
DR   A7ZSW5, GLGB_ECO24 ;  Q8X6X6, GLGB_ECO57 ;  A8A5P2, GLGB_ECOHS ;
DR   A1AGW5, GLGB_ECOK1 ;  Q0TC27, GLGB_ECOL5 ;  Q8FCR7, GLGB_ECOL6 ;
DR   B1IP32, GLGB_ECOLC ;  P07762, GLGB_ECOLI ;  Q1R5J4, GLGB_ECOUT ;
DR   Q9Y8H3, GLGB_EMENI ;  A4WFL5, GLGB_ENT38 ;  Q8GQC5, GLGB_ERWCH ;
DR   Q6CZK0, GLGB_ERWCT ;  Q6T308, GLGB_FELCA ;  B0TZI5, GLGB_FRAP2 ;
DR   Q2J6Q9, GLGB_FRASC ;  Q14J36, GLGB_FRAT1 ;  A7NAI2, GLGB_FRATF ;
DR   Q2A4U7, GLGB_FRATH ;  B2SFM7, GLGB_FRATM ;  A0Q593, GLGB_FRATN ;
DR   Q0BN67, GLGB_FRATO ;  Q5NHN4, GLGB_FRATT ;  A4IZK2, GLGB_FRATW ;
DR   Q8RF62, GLGB_FUSNN ;  P30538, GLGB_GEOSE ;  Q8NKE1, GLGB_GLOIN ;
DR   Q7NL20, GLGB_GLOVI ;  Q0BU54, GLGB_GRABC ;  Q4QK67, GLGB_HAEI8 ;
DR   A5UEJ2, GLGB_HAEIG ;  P45177, GLGB_HAEIN ;  Q0I3H7, GLGB_HAES1 ;
DR   B0UU89, GLGB_HAES2 ;  B8CVY1, GLGB_HALOH ;  Q6EAS5, GLGB_HORSE ;
DR   Q04446, GLGB_HUMAN ;  Q28MN2, GLGB_JANSC ;  A6TF51, GLGB_KLEP7 ;
DR   Q6CX53, GLGB_KLULA ;  Q5FL68, GLGB_LACAC ;  Q890J1, GLGB_LACPL ;
DR   Q1WSM8, GLGB_LACS1 ;  Q6AEU4, GLGB_LEIXX ;  Q2W2Q6, GLGB_MAGSA ;
DR   Q08047, GLGB_MAIZE ;  Q65TI0, GLGB_MANSM ;  A1U0K1, GLGB_MARAV ;
DR   Q11EX1, GLGB_MESSB ;  Q608L5, GLGB_METCA ;  Q1H1K2, GLGB_METFK ;
DR   Q9D6Y9, GLGB_MOUSE ;  P59816, GLGB_MYCBO ;  A1KIB6, GLGB_MYCBP ;
DR   Q73X75, GLGB_MYCPA ;  A3Q396, GLGB_MYCSJ ;  A1UJW9, GLGB_MYCSK ;
DR   Q1B568, GLGB_MYCSS ;  A5U226, GLGB_MYCTA ;  Q10625, GLGB_MYCTU ;
DR   A0PUI6, GLGB_MYCUA ;  Q1D654, GLGB_MYXXD ;  Q9RQI5, GLGB_NEIDE ;
DR   Q0AGJ0, GLGB_NITEC ;  Q81ZU6, GLGB_NITEU ;  Q1QNB1, GLGB_NITHX ;
DR   Q2YB47, GLGB_NITMU ;  Q3JCN0, GLGB_NITOC ;  Q3STC2, GLGB_NITWN ;
DR   Q5Z0W8, GLGB_NOCFA ;  Q8YYX9, GLGB_NOSS1 ;  Q2G7S5, GLGB_NOVAD ;
DR   Q8CZE8, GLGB_OCEIH ;  Q01401, GLGB_ORYSJ ;  Q6MAB4, GLGB_PARUW ;
DR   Q9CN94, GLGB_PASMU ;  Q6LHN1, GLGB_PHOPR ;  Q6L2Z9, GLGB_PICTO ;
DR   Q6A8Q7, GLGB_PROAC ;  A3PBV8, GLGB_PROM0 ;  A2C142, GLGB_PROM1 ;
DR   A8G3V0, GLGB_PROM2 ;  A2CAR9, GLGB_PROM3 ;  A9BAY7, GLGB_PROM4 ;
DR   A2BVP7, GLGB_PROM5 ;  Q31BV0, GLGB_PROM9 ;  Q7VBL4, GLGB_PROMA ;
DR   Q7V8B5, GLGB_PROMM ;  Q7V299, GLGB_PROMP ;  A2BQ65, GLGB_PROMS ;
DR   Q46LW6, GLGB_PROMT ;  Q48IE2, GLGB_PSE14 ;  Q15VD0, GLGB_PSEA6 ;
DR   A6V628, GLGB_PSEA7 ;  Q9I1W2, GLGB_PSEAE ;  Q4KCQ3, GLGB_PSEF5 ;
DR   Q3KD78, GLGB_PSEPF ;  Q88FN1, GLGB_PSEPK ;  Q881X0, GLGB_PSESM ;
DR   Q4ZTJ2, GLGB_PSEU2 ;  Q8XT76, GLGB_RALSO ;  Q985P4, GLGB_RHILO ;
DR   Q92M14, GLGB_RHIME ;  P52979, GLGB_RHIRD ;  Q7UVH1, GLGB_RHOBA ;
DR   Q21WG7, GLGB_RHOFD ;  Q93HU3, GLGB_RHOMR ;  Q2IYX0, GLGB_RHOP2 ;
DR   Q07K87, GLGB_RHOP5 ;  Q6N3P9, GLGB_RHOPA ;  Q210H1, GLGB_RHOPB ;
DR   Q133N2, GLGB_RHOPS ;  Q2RR72, GLGB_RHORT ;  A3PIQ5, GLGB_RHOS1 ;
DR   Q3J3M6, GLGB_RHOS4 ;  Q0SGR9, GLGB_RHOSR ;  Q165E2, GLGB_ROSDO ;
DR   Q1AZ86, GLGB_RUBXD ;  Q21M30, GLGB_SACD2 ;  A9MMA0, GLGB_SALAR ;
DR   Q57IT8, GLGB_SALCH ;  Q5PM06, GLGB_SALPA ;  A9MTV4, GLGB_SALPB ;
DR   Q2S4A0, GLGB_SALRD ;  Q8Z235, GLGB_SALTI ;  Q8ZLG5, GLGB_SALTY ;
DR   A8GKV0, GLGB_SERP5 ;  B8EAX1, GLGB_SHEB2 ;  A3D286, GLGB_SHEB5 ;
DR   A6WKY2, GLGB_SHEB8 ;  A9KTJ1, GLGB_SHEB9 ;  Q081Q4, GLGB_SHEFN ;
DR   Q8EGU7, GLGB_SHEON ;  A4Y4U3, GLGB_SHEPC ;  Q0HGI8, GLGB_SHESM ;
DR   Q0HST5, GLGB_SHESR ;  A1RLX8, GLGB_SHESW ;  Q31VJ1, GLGB_SHIBS ;
DR   Q32AV3, GLGB_SHIDS ;  Q0SZN2, GLGB_SHIF8 ;  Q83PV3, GLGB_SHIFL ;
DR   Q3YW93, GLGB_SHISS ;  P30924, GLGB_SOLTU ;  Q3K1K5, GLGB_STRA1 ;
DR   Q8E5V8, GLGB_STRA3 ;  Q8E081, GLGB_STRA5 ;  P52980, GLGB_STRAU ;
DR   A8AYH3, GLGB_STRGC ;  Q8DT52, GLGB_STRMU ;  Q04KG8, GLGB_STRP2 ;
DR   Q97QS8, GLGB_STRPN ;  Q8DPS6, GLGB_STRR6 ;  A3CM01, GLGB_STRSV ;
DR   P16954, GLGB_SYNE7 ;  Q2JT08, GLGB_SYNJA ;  Q2JK68, GLGB_SYNJB ;
DR   Q5N4W5, GLGB_SYNP6 ;  A5GJR7, GLGB_SYNPW ;  Q7U646, GLGB_SYNPX ;
DR   A5GSG4, GLGB_SYNR3 ;  Q0I8Y2, GLGB_SYNS3 ;  Q3AYE2, GLGB_SYNS9 ;
DR   Q3AKV6, GLGB_SYNSC ;  P52981, GLGB_SYNY3 ;  Q8DLB8, GLGB_THEEB ;
DR   Q47SE7, GLGB_THEFY ;  Q31IB6, GLGB_THICR ;  Q3SH78, GLGB_THIDA ;
DR   Q114I1, GLGB_TRIEI ;  Q9KNE8, GLGB_VIBCH ;  Q5DZB8, GLGB_VIBF1 ;
DR   Q87FR0, GLGB_VIBPA ;  Q8D4P0, GLGB_VIBVU ;  Q7MG90, GLGB_VIBVY ;
DR   Q6CCT1, GLGB_YARLI ;  P32775, GLGB_YEAST ;  A1JSJ0, GLGB_YERE8 ;
DR   A7FNX5, GLGB_YERP3 ;  Q1C1D9, GLGB_YERPA ;  Q8ZA75, GLGB_YERPE ;
DR   Q1CDL3, GLGB_YERPN ;  A4TQV2, GLGB_YERPP ;  Q664I2, GLGB_YERPS ;
//
ID   2.4.1.19
DE   Cyclomaltodextrin glucanotransferase.
AN   Bacillus macerans amylase.
AN   Cyclodextrin glucanotransferase.
AN   Cyclodextrin glycosyltransferase.
CA   Cyclizes part of a (1->4)-alpha-D-glucan chain by formation of a (1->4)-
CA   alpha-D-glucosidic bond.
CC   -!- Cyclomaltodextrins (Schardinger dextrins) of various sizes (6, 7,
CC       8, etc. glucose units) are formed reversibly from starch and similar
CC       substrates.
CC   -!- Also disproportionates linear maltodextrins without cyclizing (cf.
CC       EC 2.4.1.25).
PR   PROSITE; PDOC51166;
DR   P30920, CDGT1_BACCI;  P04830, CDGT1_PAEMA;  P43379, CDGT2_BACCI;
DR   P31835, CDGT2_PAEMA;  P30921, CDGT_BAC11 ;  P14014, CDGT_BACLI ;
DR   P27036, CDGT_BACOH ;  P05618, CDGT_BACS0 ;  P31746, CDGT_BACS2 ;
DR   P09121, CDGT_BACS3 ;  P17692, CDGT_BACS8 ;  P31747, CDGT_BACSS ;
DR   O30565, CDGT_BREBE ;  P31797, CDGT_GEOSE ;  P08704, CDGT_KLEOX ;
DR   P26827, CDGT_THETU ;
//
ID   2.4.1.20
DE   Cellobiose phosphorylase.
CA   Cellobiose + phosphate = alpha-D-glucose 1-phosphate + D-glucose.
//
ID   2.4.1.21
DE   Starch synthase.
AN   ADP-glucose--starch glucosyltransferase.
AN   Glycogen synthase.
AN   Starch (bacterial glycogen) synthase.
CA   ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-
CA   glucosyl)(n+1).
CC   -!- The description (official name) various according to the source of
CC       the enzyme and the nature of its synthetic product, e.g. starch
CC       synthase, bacterial glycogen synthase.
CC   -!- A similar enzyme utilizes UDP-glucose (cf. EC 2.4.1.11).
DR   P0A3F2, GLGA1_AGRT5;  Q3M9U1, GLGA1_ANAVT;  Q89RJ4, GLGA1_BRAJA;
DR   Q39XS5, GLGA1_GEOMG;  Q74ED9, GLGA1_GEOSL;  Q608L4, GLGA1_METCA;
DR   Q3JEW3, GLGA1_NITOC;  Q8YVU5, GLGA1_NOSS1;  P58393, GLGA1_RHIME;
DR   P0A3F3, GLGA1_RHIRD;  Q2JSZ9, GLGA1_SYNJA;  Q2JNM6, GLGA1_SYNJB;
DR   P74521, GLGA1_SYNY3;  Q8UK38, GLGA2_AGRT5;  Q3M3R4, GLGA2_ANAVT;
DR   Q89G86, GLGA2_BRAJA;  Q39QT6, GLGA2_GEOMG;  Q747K8, GLGA2_GEOSL;
DR   Q604D9, GLGA2_METCA;  Q3JD12, GLGA2_NITOC;  Q8Z0Q9, GLGA2_NOSS1;
DR   P58394, GLGA2_RHIME;  Q2JRJ4, GLGA2_SYNJA;  Q2JKU0, GLGA2_SYNJB;
DR   P72623, GLGA2_SYNY3;  A9NFK6, GLGA_ACHLI ;  A1TRG5, GLGA_ACIAC ;
DR   Q1ILA0, GLGA_ACIBL ;  A5FUS8, GLGA_ACICJ ;  A3MZ67, GLGA_ACTP2 ;
DR   B3H0J4, GLGA_ACTP7 ;  A6VP18, GLGA_ACTSZ ;  A0KPQ1, GLGA_AERHH ;
DR   A4SIE1, GLGA_AERS4 ;  B9JAA4, GLGA_AGRRK ;  Q0AA27, GLGA_ALHEH ;
DR   B6EQL7, GLGA_ALISL ;  A6TSC8, GLGA_ALKMQ ;  B8J8R4, GLGA_ANAD2 ;
DR   Q2IM81, GLGA_ANADE ;  A7H6L1, GLGA_ANADF ;  B4ULD8, GLGA_ANASK ;
DR   B9MPC0, GLGA_ANATD ;  B7GK04, GLGA_ANOFW ;  O66935, GLGA_AQUAE ;
DR   Q5NXZ7, GLGA_AROAE ;  Q81K85, GLGA_BACAN ;  Q72YJ6, GLGA_BACC1 ;
DR   B7HBC4, GLGA_BACC4 ;  A7GU98, GLGA_BACCN ;  B9J2G5, GLGA_BACCQ ;
DR   Q816G8, GLGA_BACCR ;  Q632H4, GLGA_BACCZ ;  Q9KDX6, GLGA_BACHD ;
DR   Q6HC18, GLGA_BACHK ;  Q65FS7, GLGA_BACLD ;  P39125, GLGA_BACSU ;
DR   Q7WIJ0, GLGA_BORBR ;  Q7W6L5, GLGA_BORPA ;  A9IMI9, GLGA_BORPD ;
DR   Q2T6R2, GLGA_BURTA ;  A4XHL5, GLGA_CALS8 ;  B3PGN5, GLGA_CELJU ;
DR   Q5L562, GLGA_CHLAB ;  Q3APL6, GLGA_CHLCH ;  Q821W4, GLGA_CHLCV ;
DR   Q255S3, GLGA_CHLFF ;  B3EGV0, GLGA_CHLL2 ;  Q9PLC3, GLGA_CHLMU ;
DR   B3QR00, GLGA_CHLP8 ;  A1BIY8, GLGA_CHLPD ;  Q9Z6V8, GLGA_CHLPN ;
DR   B0B925, GLGA_CHLT2 ;  Q3KKP3, GLGA_CHLTA ;  B0BAQ4, GLGA_CHLTB ;
DR   Q8KAY6, GLGA_CHLTE ;  O84804, GLGA_CHLTR ;  A8AQY0, GLGA_CITK8 ;
DR   Q97GX6, GLGA_CLOAB ;  A6M334, GLGA_CLOB8 ;  B2V049, GLGA_CLOBA ;
DR   B2TR28, GLGA_CLOBB ;  Q18A79, GLGA_CLOD6 ;  B9DWP3, GLGA_CLOK1 ;
DR   A5N2Z2, GLGA_CLOK5 ;  A0PY73, GLGA_CLONN ;  Q8XPA1, GLGA_CLOPE ;
DR   A9KMA3, GLGA_CLOPH ;  Q47IJ4, GLGA_DECAR ;  C1CWY8, GLGA_DEIDV ;
DR   Q1IWV2, GLGA_DEIGD ;  Q9RWS1, GLGA_DEIRA ;  B8FBH4, GLGA_DESAA ;
DR   B1I4F5, GLGA_DESAP ;  Q30Z13, GLGA_DESDG ;  B8G1G3, GLGA_DESHD ;
DR   A4J4I4, GLGA_DESRM ;  Q729V4, GLGA_DESVH ;  B8DL94, GLGA_DESVM ;
DR   A1VC53, GLGA_DESVV ;  A7ZSW2, GLGA_ECO24 ;  B7UKD4, GLGA_ECO27 ;
DR   B7MDR4, GLGA_ECO45 ;  B7L4W1, GLGA_ECO55 ;  P0A6V0, GLGA_ECO57 ;
DR   B5YUI5, GLGA_ECO5E ;  B7NMJ4, GLGA_ECO7I ;  B7N176, GLGA_ECO81 ;
DR   B7M2J2, GLGA_ECO8A ;  C4ZVX9, GLGA_ECOBW ;  B1X774, GLGA_ECODH ;
DR   A8A5N9, GLGA_ECOHS ;  A1AGW2, GLGA_ECOK1 ;  Q0TC30, GLGA_ECOL5 ;
DR   P0A6U9, GLGA_ECOL6 ;  B1IP35, GLGA_ECOLC ;  P0A6U8, GLGA_ECOLI ;
DR   B7NE39, GLGA_ECOLU ;  B6I2Z5, GLGA_ECOSE ;  B1LI90, GLGA_ECOSM ;
DR   Q1R5J7, GLGA_ECOUT ;  C5B965, GLGA_EDWI9 ;  B2KE25, GLGA_ELUMP ;
DR   A4WFL2, GLGA_ENT38 ;  A7MGE0, GLGA_ENTS8 ;  Q6CZK3, GLGA_ERWCT ;
DR   B2VJU7, GLGA_ERWT9 ;  B7LSE0, GLGA_ESCF3 ;  C4Z0G2, GLGA_EUBE2 ;
DR   B1YK70, GLGA_EXIS2 ;  C4L3L1, GLGA_EXISA ;  A7HJT8, GLGA_FERNB ;
DR   B0S264, GLGA_FINM2 ;  A5FG96, GLGA_FLAJ1 ;  B0TZI2, GLGA_FRAP2 ;
DR   Q14J34, GLGA_FRAT1 ;  A7NAI5, GLGA_FRATF ;  Q2A4U4, GLGA_FRATH ;
DR   B2SFN0, GLGA_FRATM ;  A0Q596, GLGA_FRATN ;  Q0BN64, GLGA_FRATO ;
DR   Q5NHN2, GLGA_FRATT ;  A4IZJ9, GLGA_FRATW ;  Q8RF65, GLGA_FUSNN ;
DR   O08328, GLGA_GEOSE ;  B9M2J2, GLGA_GEOSF ;  A4IS20, GLGA_GEOTN ;
DR   A5GBI7, GLGA_GEOUR ;  Q7NM37, GLGA_GLOVI ;  Q0BPL3, GLGA_GRABC ;
DR   Q4QK70, GLGA_HAEI8 ;  A5UBW8, GLGA_HAEIE ;  A5UEJ5, GLGA_HAEIG ;
DR   P45179, GLGA_HAEIN ;  B8F3S8, GLGA_HAEPS ;  Q0I3I0, GLGA_HAES1 ;
DR   A1WW18, GLGA_HALHL ;  B0TD37, GLGA_HELMI ;  B4U626, GLGA_HYDS0 ;
DR   Q28MN0, GLGA_JANSC ;  B5XTR0, GLGA_KLEP3 ;  A6TF48, GLGA_KLEP7 ;
DR   C5CGT4, GLGA_KOSOT ;  Q5FL65, GLGA_LACAC ;  Q036T0, GLGA_LACC3 ;
DR   B3W9A1, GLGA_LACCB ;  Q9CHM9, GLGA_LACLA ;  Q890I8, GLGA_LACPL ;
DR   Q1WSN1, GLGA_LACS1 ;  B0SFJ4, GLGA_LEPBA ;  B0SPF1, GLGA_LEPBP ;
DR   B1Y0P9, GLGA_LEPCP ;  Q2W5G0, GLGA_MAGSA ;  Q65TI3, GLGA_MANSM ;
DR   A1U0K2, GLGA_MARAV ;  A6VUP1, GLGA_MARMS ;  Q59001, GLGA_METJA ;
DR   B8EN59, GLGA_METSB ;  Q2RH55, GLGA_MOOTA ;  Q6KHP2, GLGA_MYCMO ;
DR   Q1DCS0, GLGA_MYXXD ;  B2A6E4, GLGA_NATTJ ;  Q0AIE6, GLGA_NITEC ;
DR   Q82SP3, GLGA_NITEU ;  Q2YB48, GLGA_NITMU ;  B2J471, GLGA_NOSP7 ;
DR   Q2G7S7, GLGA_NOVAD ;  Q8ET54, GLGA_OCEIH ;  B1ZUX5, GLGA_OPITP ;
DR   A1BAE6, GLGA_PARDP ;  Q6MAS9, GLGA_PARUW ;  Q9CN91, GLGA_PASMU ;
DR   C6DH76, GLGA_PECCP ;  Q3A0B8, GLGA_PELCD ;  Q3B6C3, GLGA_PELLD ;
DR   B4SC83, GLGA_PELPB ;  A9BG68, GLGA_PETMO ;  Q6LKA1, GLGA_PHOPR ;
DR   A1VL96, GLGA_POLNA ;  B4S584, GLGA_PROA2 ;  A3PBY3, GLGA_PROM0 ;
DR   A2C167, GLGA_PROM1 ;  A8G3X5, GLGA_PROM2 ;  A2CAW5, GLGA_PROM3 ;
DR   A9BAW0, GLGA_PROM4 ;  A2BVS2, GLGA_PROM5 ;  Q31BS5, GLGA_PROM9 ;
DR   Q7VBP0, GLGA_PROMA ;  Q7V8F0, GLGA_PROMM ;  Q7V275, GLGA_PROMP ;
DR   A2BQ90, GLGA_PROMS ;  Q46LU1, GLGA_PROMT ;  A4SCU9, GLGA_PROVI ;
DR   Q48JG9, GLGA_PSE14 ;  A6V616, GLGA_PSEA7 ;  Q9I1V0, GLGA_PSEAE ;
DR   Q4KCP0, GLGA_PSEF5 ;  Q3KD65, GLGA_PSEPF ;  Q88FN9, GLGA_PSEPK ;
DR   Q880M9, GLGA_PSESM ;  Q4ZS46, GLGA_PSEU2 ;  Q8XT73, GLGA_RALSO ;
DR   B3Q001, GLGA_RHIE6 ;  Q2K485, GLGA_RHIEC ;  Q1MBS7, GLGA_RHIL3 ;
DR   Q985P2, GLGA_RHILO ;  B5ZQ47, GLGA_RHILW ;  Q9EUT5, GLGA_RHITR ;
DR   Q7UPY2, GLGA_RHOBA ;  B6IUD9, GLGA_RHOCS ;  Q221N9, GLGA_RHOFD ;
DR   Q2J308, GLGA_RHOP2 ;  Q07TH8, GLGA_RHOP5 ;  Q6NCT7, GLGA_RHOPA ;
DR   Q21BQ1, GLGA_RHOPB ;  Q13EA7, GLGA_RHOPS ;  B3Q9C2, GLGA_RHOPT ;
DR   Q2RS50, GLGA_RHORT ;  Q9RNH6, GLGA_RHOS4 ;  A4WRM2, GLGA_RHOS5 ;
DR   Q165E4, GLGA_ROSDO ;  B5F8Q1, GLGA_SALA4 ;  A9MMA3, GLGA_SALAR ;
DR   Q57IU1, GLGA_SALCH ;  B5FKF4, GLGA_SALDC ;  B5R394, GLGA_SALEP ;
DR   B4T867, GLGA_SALHS ;  B4SVN2, GLGA_SALNS ;  Q5PM09, GLGA_SALPA ;
DR   A9MTV1, GLGA_SALPB ;  C0Q0K9, GLGA_SALPC ;  B5BHH9, GLGA_SALPK ;
DR   B4TY86, GLGA_SALSV ;  Q8Z232, GLGA_SALTI ;  P05416, GLGA_SALTY ;
DR   A8GKU7, GLGA_SERP5 ;  B2U4G3, GLGA_SHIB3 ;  Q31VJ4, GLGA_SHIBS ;
DR   Q32AV6, GLGA_SHIDS ;  Q0SZN5, GLGA_SHIF8 ;  Q83PV4, GLGA_SHIFL ;
DR   Q3YW96, GLGA_SHISS ;  Q3K1K2, GLGA_STRA1 ;  Q8E5V5, GLGA_STRA3 ;
DR   Q8E079, GLGA_STRA5 ;  C0M712, GLGA_STRE4 ;  A8AYH0, GLGA_STRGC ;
DR   Q8CWX0, GLGA_STRMU ;  Q04KG5, GLGA_STRP2 ;  B5E4N6, GLGA_STRP4 ;
DR   C1C7B7, GLGA_STRP7 ;  B1IBR0, GLGA_STRPI ;  B8ZPW5, GLGA_STRPJ ;
DR   Q97QS5, GLGA_STRPN ;  B2IPY4, GLGA_STRPS ;  Q8DPS3, GLGA_STRR6 ;
DR   C0MH77, GLGA_STRS7 ;  A3CM04, GLGA_STRSV ;  B9DRS8, GLGA_STRU0 ;
DR   C1CEB0, GLGA_STRZJ ;  C1CKI7, GLGA_STRZP ;  C1CRM3, GLGA_STRZT ;
DR   B2V5P9, GLGA_SULSY ;  Q935Y7, GLGA_SYNE7 ;  Q5N1P1, GLGA_SYNP6 ;
DR   A5GKI7, GLGA_SYNPW ;  Q7U7I2, GLGA_SYNPX ;  A5GT38, GLGA_SYNR3 ;
DR   Q0I9Y8, GLGA_SYNS3 ;  Q3AVF9, GLGA_SYNS9 ;  Q3AKK1, GLGA_SYNSC ;
DR   B7IFD0, GLGA_THEAB ;  P58395, GLGA_THECA ;  Q8DKU2, GLGA_THEEB ;
DR   A8F720, GLGA_THELT ;  A6LJ53, GLGA_THEM4 ;  Q9WZZ7, GLGA_THEMA ;
DR   A5IIN8, GLGA_THEP1 ;  B1LC39, GLGA_THESQ ;  Q72G68, GLGA_THET2 ;
DR   Q5SMC5, GLGA_THET8 ;  B5YG91, GLGA_THEYD ;  Q31IB5, GLGA_THICR ;
DR   Q3SH79, GLGA_THIDA ;  B8GNA4, GLGA_THISH ;  Q73MC7, GLGA_TREDE ;
DR   Q113E3, GLGA_TRIEI ;  C5CJ75, GLGA_VARPS ;  A5F7G0, GLGA_VIBC3 ;
DR   Q9KRB6, GLGA_VIBCH ;  C3LN49, GLGA_VIBCM ;  Q5DZC1, GLGA_VIBF1 ;
DR   B5EUW2, GLGA_VIBFM ;  Q87QX5, GLGA_VIBPA ;  B7VM42, GLGA_VIBSL ;
DR   Q8DAR0, GLGA_VIBVU ;  Q7MJ50, GLGA_VIBVY ;  Q8PQA3, GLGA_XANAC ;
DR   Q3BYI1, GLGA_XANC5 ;  Q4UZL8, GLGA_XANC8 ;  Q8PDD2, GLGA_XANCP ;
DR   Q2P9F6, GLGA_XANOM ;  B2SVT3, GLGA_XANOP ;  Q5H6Q4, GLGA_XANOR ;
DR   A1JSI5, GLGA_YERE8 ;  A7FNX2, GLGA_YERP3 ;  Q1C1E2, GLGA_YERPA ;
DR   B2K6F8, GLGA_YERPB ;  Q8ZA78, GLGA_YERPE ;  A9R5M0, GLGA_YERPG ;
DR   Q1CDL6, GLGA_YERPN ;  A4TQU9, GLGA_YERPP ;  Q664I5, GLGA_YERPS ;
DR   B1JHY0, GLGA_YERPY ;  O82627, SSG1_ANTMA ;  Q43093, SSG2_PEA   ;
DR   Q9FNF2, SSY1_ARATH ;  A2Y9M4, SSY1_ORYSI ;  Q0DEC8, SSY1_ORYSJ ;
DR   P93568, SSY1_SOLTU ;  Q43654, SSY1_WHEAT ;  Q7XE48, SSY21_ORYSJ;
DR   Q6Z2T8, SSY22_ORYSJ;  P0C586, SSY23_ORYSI;  Q0DDE3, SSY23_ORYSJ;
DR   Q43847, SSY2_SOLTU ;  Q43846, SSY3_SOLTU ;
//
ID   2.4.1.22
DE   Lactose synthase.
AN   N-acetyllactosamine synthase.
AN   UDP-galactose--glucose galactosyltransferase.
CA   UDP-galactose + D-glucose = UDP + lactose.
CC   -!- The enzyme is a complex of 2 proteins A and B.
CC   -!- In the absence of the B protein (alpha-lactalbumin) the enzyme
CC       catalyzes the transfer of galactose from UDP-galactose to
CC       N-acetylglucosamine (cf. EC 2.4.1.90).
DR   P08037, B4GT1_BOVIN;  P15291, B4GT1_HUMAN;  P15535, B4GT1_MOUSE;
DR   P80225, B4GT1_RAT  ;  Q80WN9, B4GT2_CRIGR;  O60909, B4GT2_HUMAN;
DR   Q9Z2Y2, B4GT2_MOUSE;
//
ID   2.4.1.23
DE   Sphingosine beta-galactosyltransferase.
AN   Psychosine--UDP galactosyltransferase.
CA   UDP-galactose + sphingosine = UDP + psychosine.
//
ID   2.4.1.24
DE   1,4-alpha-glucan 6-alpha-glucosyltransferase.
AN   Oligoglucan-branching glycosyltransferase.
CA   Transfers an alpha-D-glucosyl residue in a (1->4)-alpha-D-glucan to the
CA   primary hydroxy group of glucose, free or combined in a (1->4)-alpha-D-
CA   glucan.
//
ID   2.4.1.25
DE   4-alpha-glucanotransferase.
AN   D-enzyme.
AN   Dextrin glycosyltransferase.
AN   Disproportionating enzyme.
AN   Oligo-1,4-1,4-glucantransferase.
CA   Transfers a segment of a (1->4)-alpha-D-glucan to a new position in an
CA   acceptor, which may be glucose or a (1->4)-alpha-D-glucan.
CC   -!- An enzymic activity of this nature forms part of the mammalian and
CC       Saccharomyces cerevisiae glycogen branching system (see EC 3.2.1.33).
CC   -!- Formerly EC 2.4.1.3.
DR   Q9LV91, DPE1_ARATH ;  Q8LI30, DPE1_ORYSJ ;  Q8RXD9, DPE2_ARATH ;
DR   Q69Q02, DPE2_ORYSJ ;  Q06801, DPEP_SOLTU ;  Q2PQH8, GDE_CANFA  ;
DR   A8BQB4, GDE_HORSE  ;  P35573, GDE_HUMAN  ;  P35574, GDE_RABIT  ;
DR   Q06625, GDE_YEAST  ;  O66937, MALQ_AQUAE ;  O34022, MALQ_CHLCV ;
DR   Q9PKU9, MALQ_CHLMU ;  Q9Z8L2, MALQ_CHLPN ;  O84089, MALQ_CHLTR ;
DR   Q59266, MALQ_CLOBU ;  P15977, MALQ_ECOLI ;  P45176, MALQ_HAEIN ;
DR   P65337, MALQ_MYCBO ;  P65336, MALQ_MYCTU ;  O32450, MALQ_PYRKO ;
DR   P0A3Q0, MALQ_STRPN ;  P0A3Q1, MALQ_STRR6 ;  P72785, MALQ_SYNY3 ;
DR   O32462, MALQ_THELI ;  O87172, MALQ_THETH ;  P80099, MGTA_THEMA ;
DR   O86956, MGTA_THENE ;
//
ID   2.4.1.26
DE   DNA alpha-glucosyltransferase.
CA   Transfers an alpha-D-glucosyl residue from UDP-glucose to an
CA   hydroxymethylcytosine residue in DNA.
DR   P04519, GSTA_BPT4  ;
//
ID   2.4.1.27
DE   DNA beta-glucosyltransferase.
CA   Transfers a beta-D-glucosyl residue from UDP-glucose to an
CA   hydroxymethylcytosine residue in DNA.
DR   P04547, GSTB_BPT4  ;
//
ID   2.4.1.28
DE   Glucosyl-DNA beta-glucosyltransferase.
CA   Transfers a beta-D-glucosyl residue from UDP-glucose to a
CA   glucosylhydroxymethylcytosine residue in DNA.
//
ID   2.4.1.29
DE   Cellulose synthase (GDP-forming).
AN   GDP-glucose-beta-D-glucan glucosyltransferase.
AN   GDP-glucose-cellulose glucosyltransferase.
CA   GDP-glucose + ((1->4)-beta-D-glucosyl)(n) = GDP + ((1->4)-beta-D-
CA   glucosyl)(n+1).
CC   -!- Involved in the synthesis of cellulose.
CC   -!- A similar enzyme utilizes UDP-glucose (cf. EC 2.4.1.12).
//
ID   2.4.1.30
DE   1,3-beta-oligoglucan phosphorylase.
AN   Beta-1,3-oligoglucan:orthophosphate glucosyltransferase II.
CA   ((1->3)-beta-D-glucosyl)(n) + phosphate = ((1->3)-beta-D-glucosyl)(n-1) +
CA   alpha-D-glucose 1-phosphate.
CC   -!- Does not act on laminarin.
CC   -!- Differs in specificity from EC 2.4.1.31 and EC 2.4.1.97.
//
ID   2.4.1.31
DE   Laminaribiose phosphorylase.
CA   3-beta-D-glucosyl-D-glucose + phosphate = D-glucose + alpha-D-glucose
CA   1-phosphate.
CC   -!- Also acts on 1,3-beta-D-oligoglucans.
CC   -!- Differs in specificity from EC 2.4.1.30 and EC 2.4.1.97.
//
ID   2.4.1.32
DE   Glucomannan 4-beta-mannosyltransferase.
AN   Glucomannan-synthase.
CA   GDP-mannose + (glucomannan)(n) = GDP + (glucomannan)(n+1).
DR   Q7PC76, CSLA1_ORYSJ;  Q9FNI7, CSLA2_ARATH;  Q9LZR3, CSLA9_ARATH;
//
ID   2.4.1.33
DE   Alginate synthase.
AN   Mannuronosyl transferase.
CA   GDP-D-mannuronate + (alginate)(n) = GDP + (alginate)(n+1).
//
ID   2.4.1.34
DE   1,3-beta-glucan synthase.
AN   1,3-beta-D-glucan--UDP glucosyltransferase.
AN   1,3-beta-D-glucan-UDP glucosyltransferase.
AN   Callose synthase.
AN   Callose synthetase.
AN   UDP-glucose--3-beta-D-glucan glucosyltransferase.
AN   UDP-glucose-1,3-beta-D-glucan glucosyltransferase.
CA   UDP-glucose + ((1->3)-beta-D-glucosyl)(n) = UDP + ((1->3)-beta-D-
CA   glucosyl)(n+1).
DR   Q10287, BGS1_SCHPO ;  O13967, BGS2_SCHPO ;  Q9P377, BGS3_SCHPO ;
DR   O74475, BGS4_SCHPO ;  Q9AUE0, CALS1_ARATH;  Q9SL03, CALS2_ARATH;
DR   Q9LXT9, CALS3_ARATH;  Q9LTG5, CALS4_ARATH;  Q3B724, CALS5_ARATH;
DR   Q9LYS6, CALS6_ARATH;  Q9SHJ3, CALS7_ARATH;  Q9LUD7, CALS8_ARATH;
DR   Q9SFU6, CALS9_ARATH;  Q9SJM0, CALSA_ARATH;  Q9S9U0, CALSB_ARATH;
DR   Q9ZT82, CALSC_ARATH;  A2QLK4, FKS1_ASPNC ;  O93927, FKS1_CRYNV ;
DR   P38631, FKS1_YEAST ;  P40989, FKS2_YEAST ;  Q04952, FKS3_YEAST ;
//
ID   2.4.1.35
DE   Phenol beta-glucosyltransferase.
AN   UDP-glucosyltransferase.
CA   UDP-glucose + a phenol = UDP + an aryl beta-D-glucoside.
CC   -!- Acts on a wide range of phenols.
//
ID   2.4.1.36
DE   Alpha,alpha-trehalose-phosphate synthase (GDP-forming).
AN   GDP-glucose-glucosephosphate glucosyltransferase.
AN   Trehalose phosphate synthase (GDP-forming).
CA   GDP-glucose + glucose 6-phosphate = GDP + alpha,alpha-trehalose
CA   6-phosphate.
CC   -!- See also EC 2.4.1.15.
//
ID   2.4.1.37
DE   Fucosylgalactoside 3-alpha-galactosyltransferase.
AN   [Blood group substance] alpha-galactosyltransferase.
AN   B transferase.
AN   Blood-group substance alpha-dependent galactosyltransferase.
AN   Blood-group substance B-dependent galactosyltransferase.
AN   Fucosylglycoprotein 3-alpha-galactosyltransferase.
AN   Glycoprotein-fucosylgalactoside alpha-galactosyltransferase.
AN   Histo-blood group B transferase.
AN   Histo-blood substance alpha-dependent galactosyltransferase.
AN   UDPgalactose:glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose 3-alpha-D-
AN   galactosyltransferase.
AN   UDPgalactose:O-alpha-L-fucosyl(1->2)D-galactose alpha-D-
AN   galactosyltransferase.
CA   UDP-galactose + alpha-L-fucosyl-(1->2)-D-galactosyl-R = UDP + alpha-D-
CA   galactosyl-(1->3)-(alpha-L-fucosyl-(1->2))-D-galactosyl-R.
CC   -!- Acts on blood group substance, and can use a number of 2-fucosyl-
CC       galactosides as acceptors.
DR   Q54RP0, AGTA_DICDI ;  Q9ET32, BGAT1_RAT  ;  Q8CFC4, BGAT2_RAT  ;
DR   P16442, BGAT_HUMAN ;  P38649, BGAT_MOUSE ;
//
ID   2.4.1.38
DE   Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase.
AN   GalT.
AN   Glycoprotein 4-beta-galactosyltransferase.
AN   Thyroid galactosyltransferase.
AN   UDP-galactose--glycoprotein galactosyltransferase.
CA   UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-
CA   galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide.
CC   -!- Terminal N-acetyl-beta-D-glucosaminyl residues in polysaccharides,
CC       glycoproteins and glycopeptides can act as acceptor.
CC   -!- High activity is shown toward such residues in branched-chain
CC       polysaccharides when these are linked by beta-1,6 links to galactose
CC       residues; lower activity toward residues linked to galactose by beta-
CC       1,3 links.
CC   -!- A component of EC 2.4.1.22.
DR   P08037, B4GT1_BOVIN;  P15291, B4GT1_HUMAN;  P15535, B4GT1_MOUSE;
DR   P80225, B4GT1_RAT  ;  Q80WN9, B4GT2_CRIGR;  O60909, B4GT2_HUMAN;
DR   Q9Z2Y2, B4GT2_MOUSE;  Q5EA87, B4GT3_BOVIN;  Q80WN8, B4GT3_CRIGR;
DR   O60512, B4GT3_HUMAN;  Q91YY2, B4GT3_MOUSE;  Q5NVN3, B4GT3_PONAB;
DR   Q6P768, B4GT3_RAT  ;
//
ID   2.4.1.39
DE   Steroid N-acetylglucosaminyltransferase.
AN   Sucrose-glucan glucosyltransferase.
CA   UDP-N-acetyl-D-glucosamine + estradiol-17-alpha 3-D-glucuronoside = UDP +
CA   17-alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside.
//
ID   2.4.1.40
DE   Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase.
AN   A transferase.
AN   Fucosylgalactose alpha-N-acetylgalactosaminyltransferase.
AN   Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase.
AN   Histo-blood group A acetylgalactosaminyltransferase.
AN   Histo-blood group A transferase.
CA   UDP-N-acetyl-D-galactosamine + glycoprotein-alpha-L-fucosyl-(1->2)-D-
CA   galactose = UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1->3)-
CA   (alpha-L-fucosyl-(1->2))-D-galactose.
CC   -!- Acts on blood group substance H.
CC   -!- Can use a number of 2-fucosyl-galactosides as acceptors.
DR   Q9ET32, BGAT1_RAT  ;  Q8CFC4, BGAT2_RAT  ;  P16442, BGAT_HUMAN ;
DR   P38649, BGAT_MOUSE ;
//
ID   2.4.1.41
DE   Polypeptide N-acetylgalactosaminyltransferase.
AN   Protein-UDP acetylgalactosaminyltransferase.
CA   UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-
CA   galactosaminyl-polypeptide.
CF   Calcium; Manganese.
CC   -!- The glycosyl residue is transferred to threonine or serine hydroxy
CC       groups on the polypeptide core of submaxillary mucin, kappa-casein,
CC       apofetuin and some other acceptors of high molecular mass.
DR   Q07537, GALT1_BOVIN;  Q6WV20, GALT1_DROME;  Q10472, GALT1_HUMAN;
DR   O08912, GALT1_MOUSE;  Q29121, GALT1_PIG  ;  Q10473, GALT1_RAT  ;
DR   Q6WV19, GALT2_DROME;  Q10471, GALT2_HUMAN;  Q6PB93, GALT2_MOUSE;
DR   P34678, GALT3_CAEEL;  Q9Y117, GALT3_DROME;  Q14435, GALT3_HUMAN;
DR   P70419, GALT3_MOUSE;  Q8I136, GALT4_CAEEL;  Q8N4A0, GALT4_HUMAN;
DR   O08832, GALT4_MOUSE;  Q95ZJ1, GALT5_CAEEL;  Q6WV17, GALT5_DROME;
DR   Q7Z7M9, GALT5_HUMAN;  Q8C102, GALT5_MOUSE;  O88422, GALT5_RAT  ;
DR   Q5EA41, GALT6_BOVIN;  Q8NCL4, GALT6_HUMAN;  Q8C7U7, GALT6_MOUSE;
DR   Q9VUT6, GALT8_DROME;  Q9NY28, GALT8_HUMAN;  Q8MRC9, GALT9_DROME;
DR   Q9HCQ5, GALT9_HUMAN;  Q9GM01, GALT9_MACFA;  A8Y236, GLT10_CAEBR;
DR   O45947, GLT10_CAEEL;  Q8IA43, GLT10_DROME;  Q86SR1, GLT10_HUMAN;
DR   Q6P9S7, GLT10_MOUSE;  Q925R7, GLT10_RAT  ;  Q7K755, GLT11_CAEEL;
DR   Q8IA41, GLT11_DROME;  Q8NCW6, GLT11_HUMAN;  Q921L8, GLT11_MOUSE;
DR   Q6P6V1, GLT11_RAT  ;  Q8IA44, GLT12_DROME;  Q8IXK2, GLT12_HUMAN;
DR   Q8BGT9, GLT12_MOUSE;  Q8MYY6, GLT13_DROME;  Q8IUC8, GLT13_HUMAN;
DR   Q8CF93, GLT13_MOUSE;  Q6UE39, GLT13_RAT  ;  Q96FL9, GLT14_HUMAN;
DR   Q8BVG5, GLT14_MOUSE;  Q8MVS5, GLT35_DROME;  Q8N428, GLTL1_HUMAN;
DR   Q9JJ61, GLTL1_MOUSE;  Q8N3T1, GLTL2_HUMAN;  Q9D2N8, GLTL2_MOUSE;
DR   Q6IS24, GLTL3_HUMAN;  Q7TT15, GLTL3_MOUSE;  Q6P9A2, GLTL4_HUMAN;
DR   Q8K1B9, GLTL4_MOUSE;  Q49A17, GLTL6_HUMAN;
//
ID   2.4.1.42
DE   Transferred entry: 2.4.1.17.
//
ID   2.4.1.43
DE   Polygalacturonate 4-alpha-galacturonosyltransferase.
CA   UDP-D-galacturonate + ((1->4)-alpha-D-galacturonosyl)(n) = UDP + ((1->4)-
CA   alpha-D-galacturonosyl)(n+1).
//
ID   2.4.1.44
DE   Lipopolysaccharide 3-alpha-galactosyltransferase.
AN   Lipopolysaccharide 1,3-galactosyltransferase.
AN   Lipopolysaccharide galactosyltransferase.
AN   UDP-galactose:lipopolysaccharide alpha,3-galactosyltransferase.
AN   UDP-galactose:polysaccharide galactosyltransferase.
AN   Uridine diphosphate galactose:lipopolysaccharide alpha-3-
AN   galactosyltransferase.
AN   Uridine diphosphogalactose-lipopolysaccharide alpha,3-
AN   galactosyltransferase.
CA   UDP-galactose + lipopolysaccharide = UDP + 3-alpha-D-galactosyl-
CA   [lipopolysaccharide glucose].
CC   -!- Transfers D-galactosyl residues to D-glucose in the partially
CC       completed core of lipopolysaccharide (cf. EC 2.4.1.56, EC 2.4.1.58,
CC       and EC 2.4.1.73).
DR   P27128, RFAI_ECOLI ;  P19816, RFAI_SALTY ;
//
ID   2.4.1.45
DE   2-hydroxyacylsphingosine 1-beta-galactosyltransferase.
AN   Cerebroside synthase.
AN   UDP-galactose-ceramide galactosyltransferase.
CA   UDP-galactose + 2-(2-hydroxyacyl)sphingosine = UDP + 1-(beta-D-
CA   galactosyl)-2-(2-hydroxyacyl)sphingosine.
CC   -!- Highly specific.
PR   PROSITE; PDOC00359;
DR   Q16880, CGT_HUMAN  ;  Q64676, CGT_MOUSE  ;  Q09426, CGT_RAT    ;
//
ID   2.4.1.46
DE   Monogalactosyldiacylglycerol synthase.
AN   1,2-diacylglycerol 3-beta-galactosyltransferase.
AN   1-beta-MGDG.
AN   MGDG synthase.
AN   UDP galactose-1,2-diacylglycerol galactosyltransferase.
AN   UDP-galactose-diacylglyceride galactosyltransferase.
AN   UDP-galactose:diacylglycerol galactosyltransferase.
AN   UDPgalactose:1,2-diacylglycerol 3-beta-D-galactosyltransferase.
AN   Uridine diphosphogalactose-1,2-diacylglycerol galactosyltransferase.
CA   UDP-galactose + 1,2-diacyl-sn-glycerol = UDP + 3-beta-D-galactosyl-1,2-
CA   diacyl-sn-glycerol.
CC   -!- This enzyme adds only one galactosyl group to the diacylglycerol;
CC       EC 2.4.1.241 adds a galactosyl group to the product of the above
CC       reaction.
CC   -!- There are three isoforms in Arabidopsis that can be divided into two
CC       types, A-type (MGD1) and B-type (MGD2 and MGD3).
CC   -!- MGD1 is the isoform responsible for the bulk of
CC       monogalactosyldiacylglycerol (MGDG) synthesis in Arabidopsis.
DR   O81770, MGDG1_ARATH;  Q69QJ7, MGDG1_ORYSJ;  O82730, MGDG2_ARATH;
DR   A2YTP9, MGDG2_ORYSI;  Q6UTZ2, MGDG2_ORYSJ;  Q9SI93, MGDG3_ARATH;
DR   Q0DWQ1, MGDG3_ORYSJ;  P93115, MGDG_CUCSA ;  Q9FZL4, MGDG_SOYBN ;
DR   Q9SM44, MGDG_SPIOL ;  Q9FZL3, MGDG_TOBAC ;
//
ID   2.4.1.47
DE   N-acylsphingosine galactosyltransferase.
CA   UDP-galactose + N-acylsphingosine = UDP + D-galactosylceramide.
//
ID   2.4.1.48
DE   Heteroglycan alpha-mannosyltransferase.
CA   GDP-mannose + heteroglycan = GDP + 2(or 3)-alpha-D-mannosyl-heteroglycan.
CC   -!- The acceptor is a heteroglycan primer containing mannose, galactose
CC       and xylose.
CC   -!- 1,2- and 1,3-mannosyl bonds are formed.
//
ID   2.4.1.49
DE   Cellodextrin phosphorylase.
CA   ((1->4)-beta-D-glucosyl)(n) + phosphate = ((1->4)-beta-D-glucosyl)(n-1) +
CA   alpha-D-glucose 1-phosphate.
//
ID   2.4.1.50
DE   Procollagen galactosyltransferase.
AN   Hydroxylysine galactosyltransferase.
CA   UDP-galactose + 5-hydroxy-L-lysine-[procollagen] = UDP +
CA   5-(D-galactosyloxy)-L-lysine-[procollagen].
CC   -!- Probably involved in the synthesis of carbohydrate units in
CC       complement (cf. EC 2.4.1.66).
DR   A0JPH3, G251A_XENLA;  Q5U483, G251B_XENLA;  A5PK45, GT251_BOVIN;
DR   A5PMF6, GT251_DANRE;  Q8NBJ5, GT251_HUMAN;  Q8K297, GT251_MOUSE;
DR   Q8IYK4, GT252_HUMAN;  Q6NVG7, GT252_MOUSE;
//
ID   2.4.1.51
DE   Transferred entry: 2.4.1.101, 2.4.1.143, 2.4.1.144 and 2.4.1.145.
//
ID   2.4.1.52
DE   Poly(glycerol-phosphate) alpha-glucosyltransferase.
CA   UDP-glucose + poly(glycerol phosphate) = UDP + O-(alpha-D-
CA   glucosyl)poly(glycerol phosphate).
DR   P13484, TAGE_BACSU ;
//
ID   2.4.1.53
DE   Poly(ribitol-phosphate) beta-glucosyltransferase.
CA   UDP-glucose + poly(ribitol phosphate) = UDP + (beta-D-
CA   glucosyl)poly(ribitol phosphate).
//
ID   2.4.1.54
DE   Undecaprenyl-phosphate mannosyltransferase.
CA   GDP-mannose + undecaprenyl phosphate = GDP + D-mannosyl-1-
CA   phosphoundecaprenol.
CC   -!- Requires phosphatidylglycerol.
//
ID   2.4.1.55
DE   Transferred entry: 2.7.8.14.
//
ID   2.4.1.56
DE   Lipopolysaccharide N-acetylglucosaminyltransferase.
CA   UDP-N-acetyl-D-glucosamine + lipopolysaccharide = UDP + N-acetyl-D-
CA   glucosaminyllipopolysaccharide.
CC   -!- Transfers N-acetylglucosaminyl residues to a D-galactose residue in
CC       the partially completed lipopolysaccharide core (cf. EC 2.4.1.44,
CC       EC 2.4.1.58, and EC 2.4.1.73).
DR   P26470, WAAK_SALTY ;  P27242, WAAU_ECOLI ;
//
ID   2.4.1.57
DE   Phosphatidylinositol alpha-mannosyltransferase.
AN   GDP mannose-phosphatidyl-myo-inositol alpha-mannosyltransferase.
AN   GDPmannose:1-phosphatidyl-myo-inositol alpha-D-mannosyltransferase.
AN   Guanosine diphosphomannose-phosphatidyl-inositol alpha-
AN   mannosyltransferase.
AN   Phosphatidyl-myo-inositol alpha-mannosyltransferase.
CA   Transfers one or more alpha-D-mannose residues from GDP-mannose to
CA   positions 2,6 and others in 1-phosphatidyl-myo-inositol.
DR   Q7TY88, PIMA_MYCBO ;  O07147, PIMA_MYCLE ;  A0QWG6, PIMA_MYCS2 ;
DR   O06204, PIMA_MYCTU ;  Q8NNK8, PIMB_CORGL ;  A0R043, PIMB_MYCS2 ;
DR   O53522, PIMB_MYCTU ;  A5U3B9, PIMC_MYCTA ;  P0CF99, PIMC_MYCTU ;
//
ID   2.4.1.58
DE   Lipopolysaccharide glucosyltransferase I.
CA   UDP-glucose + lipopolysaccharide = UDP + D-glucosyl-lipopolysaccharide.
CC   -!- Transfers glucosyl residues to the backbone portion of
CC       lipopolysaccharide (cf. EC 2.4.1.44, EC 2.4.1.56, and EC 2.4.1.73).
DR   P27129, RFAJ_ECOLI ;  P19817, RFAJ_SALTY ;
//
ID   2.4.1.59
DE   Transferred entry: 2.4.1.17.
//
ID   2.4.1.60
DE   Abequosyltransferase.
CA   CDP-abequose + D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid =
CA   CDP + D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid.
//
ID   2.4.1.61
DE   Transferred entry: 2.4.1.17.
//
ID   2.4.1.62
DE   Ganglioside galactosyltransferase.
CA   UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-
CA   galactosyl-(1->4)-beta-D-glucosyl-N-acylsphingosine = UDP + D-galactosyl-
CA   (1->3)-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-
CA   D-glucosyl-N-acylsphingosine.
CC   -!- The substrate is also known as G(M2).
DR   Q5TJE8, B3GT4_CANFA;  O96024, B3GT4_HUMAN;  Q9Z0F0, B3GT4_MOUSE;
DR   O88178, B3GT4_RAT  ;  Q24157, BRN_DROME  ;
//
ID   2.4.1.63
DE   Linamarin synthase.
CA   UDP-glucose + 2-hydroxy-2-methylpropanenitrile = UDP + linamarin.
CC   -!- Glucosylates the cyanohydrins of butanone and pentan-3-one as well as
CC       that of acetone.
//
ID   2.4.1.64
DE   Alpha,alpha-trehalose phosphorylase.
CA   Alpha,alpha-trehalose + phosphate = D-glucose + beta-D-glucose
CA   1-phosphate.
//
ID   2.4.1.65
DE   3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase.
AN   (Le(a))-dependent (alpha-3/4)-fucosyltransferase.
AN   Alpha-(1,3/1,4) fucosyltransferase III.
AN   Alpha-(1->4)-L-fucosyltransferase.
AN   Alpha-4-L-fucosyltransferase.
AN   Beta-acetylglucosaminylsaccharide fucosyltransferase.
AN   Blood group Lewis alpha-4-fucosyltransferase.
AN   Blood-group substance Le(a)-dependent fucosyltransferase.
AN   FucT-II.
AN   Galactoside 3(4)-L-fucosyltransferase.
AN   Guanosine diphosphofucose-beta-acetylglucosaminylsaccharide 4-alpha-L-
AN   fucosyltransferase.
AN   Guanosine diphosphofucose-glycoprotein 4-alpha-fucosyltransferase.
AN   Guanosine diphosphofucose-glycoprotein 4-alpha-L-fucosyltransferase.
AN   Lewis alpha-(1->3/4)-fucosyltransferase.
AN   Lewis blood group alpha-(1->3/4)-fucosyltransferase.
AN   Lewis FT.
AN   Lewis(Le) blood group gene-dependent alpha-(1->3/4)-L-fucosyltransferase.
CA   GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-D-glucosaminyl-R =
CA   GDP + beta-D-galactosyl-(1->3)-(alpha-L-fucosyl-(1->4))-N-acetyl-beta-D-
CA   glucosaminyl-R.
CC   -!- Product of the Lewis blood group gene.
CC   -!- Normally acts on a glycoconjugate where R (see CA line) is a
CC       glycoprotein or glycolipid.
CC   -!- Although it is a 4-fucosyltransferase, it has a persistent
CC       3-fucosyltransferase activity toward the glucose residue in free
CC       lactose.
CC   -!- Fucosylates on O-4 of an N-acetylglucosamine that carries a
CC       galactosyl group on O-3, unlike EC 2.4.1.152 which fucosylates on O-3
CC       of an N-acetylglucosamine that carries a galactosyl group on O-4.
CC   -!- Enzymes catalyzing the 4-alpha-fucosylation of the GlcNAc in beta-D-
CC       Gal-(1->3)-beta-GlcNAc sequences (with some activity also as 3-alpha-
CC       fucosyltransferases) are present in plants, where the function in
CC       vivo is the modification of N-glycans.
CC   -!- In addition, the fucTa gene of Helicobacter strain UA948 encodes a
CC       fucosyltransferase with both 3-alpha- and 4-alpha-fucosyltransferase
CC       activities.
DR   Q11126, FUT3_BOVIN ;  P21217, FUT3_HUMAN ;  O19058, FUT3_PANTR ;
DR   Q8HYJ5, FUT3_PONPY ;  Q8HYJ7, FUT5_GORGO ;  Q11128, FUT5_HUMAN ;
DR   Q8HYJ3, FUT5_HYLLA ;  P56433, FUT5_PANTR ;  Q8HYJ4, FUT5_PONPY ;
DR   Q8HYJ6, FUT6_GORGO ;  P51993, FUT6_HUMAN ;  P56434, FUT6_PANTR ;
DR   Q9GKU6, FUT6_PONPY ;
//
ID   2.4.1.66
DE   Procollagen glucosyltransferase.
AN   Galactosylhydroxylysine-glucosyltransferase.
CA   UDP-glucose + (2S,5R)-5-O-(beta-D-galactosyl)-5-hydroxy-lysine-
CA   [procollagen] = UDP + (2S,5R)-5-O-(alpha-D-glucosyl-(1->2)-beta-D-
CA   galactosyl)-5-hydroxy-lysine-[procollagen].
CC   -!- Probably involved in the synthesis of carbohydrate units in
CC       complement (cf. EC 2.4.1.50).
//
ID   2.4.1.67
DE   Galactinol--raffinose galactosyltransferase.
AN   Galactinol-raffinose galactosyltransferase.
AN   Stachyose synthetase.
CA   Alpha-D-galactosyl-(1->3)-1D-myo-inositol + raffinose = myo-inositol +
CA   stachyose.
CC   -!- This enzyme also catalyzes galactosyl transfer from stachyose to
CC       raffinose (shown by labelling).
CC   -!- For synthesis of the substrate, see EC 2.4.1.123.
CC   -!- See also EC 2.4.1.82.
DR   Q93XK2, STSYN_PEA  ;
//
ID   2.4.1.68
DE   Glycoprotein 6-alpha-L-fucosyltransferase.
AN   GDP-fucose--glycoprotein fucosyltransferase.
AN   GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1->6)fucosyltransferase.
AN   GDP-L-fucose-glycoprotein fucosyltransferase.
AN   Glycoprotein fucosyltransferase.
AN   Guanosine diphosphofucose-glycoprotein fucosyltransferase.
CA   GDP-beta-L-fucose + N(4)-(N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-
CA   mannosyl-(1->3)-(N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-
CA   (1->6))-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-
CA   acetyl-beta-D-glucosaminyl)asparagine = GDP + N(4)-(N-acetyl-beta-D-
CA   glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-(N-acetyl-beta-D-
CA   glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6))-beta-D-mannosyl-(1->4)-N-
CA   acetyl-beta-D-glucosaminyl-(1->4)-(alpha-L-fucosyl-(1->6))-N-acetyl-beta-
CA   D-glucosaminyl)asparagine.
CC   -!- Catalyzes a reaction similar to that of EC 2.4.1.214, but transfers
CC       the L-fucosyl group from GDP-beta-L-fucose to form an alpha-1,6-
CC       linkage rather than an alpha-1,3-linkage.
DR   Q9N0W2, FUT8_BOVIN ;  Q659X0, FUT8_CANFA ;  Q9VYV5, FUT8_DROME ;
DR   Q9BYC5, FUT8_HUMAN ;  Q9WTS2, FUT8_MOUSE ;  Q6EV77, FUT8_PANTR ;
DR   P79282, FUT8_PIG   ;  Q5NVB3, FUT8_PONAB ;  Q6EV76, FUT8_RAT   ;
DR   Q6NVP8, FUT8_XENTR ;
//
ID   2.4.1.69
DE   Galactoside 2-alpha-L-fucosyltransferase.
AN   Alpha-(1->2)-L-fucosyltransferase.
AN   Alpha-2-fucosyltransferase.
AN   Alpha-2-L-fucosyltransferase.
AN   Beta-galactoside alpha-1->2 fucosyltransferase.
AN   Blood group H alpha-2-fucosyltransferase.
AN   Blood-group substance H-dependent fucosyltransferase.
AN   Galactoside 2-L-fucosyltransferase.
AN   GDP fucose-lactose fucosyltransferase.
AN   GDP-L-fucose:lactose fucosyltransferase.
AN   Guanosine diphospho-L-fucose-lactose fucosyltransferase.
AN   Guanosine diphosphofucose-beta-D-galactosyl-alpha-2-L-fucosyltransferase.
AN   Guanosine diphosphofucose-galactoside 2-L-fucosyltransferase.
AN   Guanosine diphosphofucose-galactosylacetylglucosaminylgalactosyl-
AN   glucosylceramide alpha-L-fucosyltransferase.
AN   Guanosine diphosphofucose-glycoprotein 2-alpha-fucosyltransferase.
AN   Guanosine diphosphofucose-glycoprotein 2-alpha-L-fucosyltransferase.
AN   Guanosine diphosphofucose-lactose fucosyltransferase.
AN   H-gene-encoded beta-galactoside alpha-1->2 fucosyltransferase.
AN   Secretor-type beta-galactoside alpha-1->2 fucosyltransferase.
CA   GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-beta-D-
CA   glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-
CA   ceramide = GDP + alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-
CA   acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-
CA   glucosyl-(1<->1)-ceramide.
CC   -!- Free lactose can act as acceptor.
CC   -!- The action on glycolipid was previously listed as EC 2.4.1.89.
DR   Q866E1, FUT1_ALOBE ;  Q866E4, FUT1_ALOCA ;  Q866E6, FUT1_AOTAZ ;
DR   Q866E7, FUT1_AOTNA ;  Q9SWH5, FUT1_ARATH ;  Q866C7, FUT1_ATEBE ;
DR   Q866C5, FUT1_CALBN ;  Q866D9, FUT1_CALHU ;  Q866E8, FUT1_CEBAP ;
DR   Q9TUD4, FUT1_GORGO ;  P19526, FUT1_HUMAN ;  Q866C9, FUT1_LAGLA ;
DR   Q866D6, FUT1_LEOCY ;  O09160, FUT1_MOUSE ;  Q9TUD6, FUT1_PANTR ;
DR   Q9M5Q1, FUT1_PEA   ;  Q29043, FUT1_PIG   ;  Q10979, FUT1_RABIT ;
DR   Q10980, FUT1_RAT   ;  Q866D2, FUT1_SAGFU ;  Q866F0, FUT1_SAIBB ;
DR   Q866F1, FUT1_SAISC ;  Q28113, FUT2_BOVIN ;  O77486, FUT2_GORGO ;
DR   Q10981, FUT2_HUMAN ;  Q9TTC7, FUT2_HYLLA ;  Q9JL27, FUT2_MOUSE ;
DR   O77485, FUT2_PANTR ;  Q10982, FUT2_PIG   ;  O77487, FUT2_PONPY ;
DR   Q10983, FUT2_RABIT ;  Q10984, FUT2_RAT   ;  Q54QG0, PGFB_DICDI ;
DR   P97353, SEC1_MOUSE ;
//
ID   2.4.1.70
DE   Poly(ribitol-phosphate) N-acetylglucosaminyltransferase.
CA   UDP-N-acetyl-D-glucosamine + poly(ribitol phosphate) = UDP + (N-acetyl-D-
CA   glucosaminyl)poly(ribitol phosphate).
CC   -!- Involved in the synthesis of teichoic acids.
//
ID   2.4.1.71
DE   Arylamine glucosyltransferase.
AN   UDP glucose-arylamine glucosyltransferase.
CA   UDP-glucose + an arylamine = UDP + an N-D-glucosylarylamine.
//
ID   2.4.1.72
DE   Transferred entry: 2.4.2.24.
//
ID   2.4.1.73
DE   Lipopolysaccharide glucosyltransferase II.
CA   UDP-glucose + lipopolysaccharide = UDP + alpha-D-glucosyl-
CA   lipopolysaccharide.
CC   -!- Transfers glucosyl residues to the D-galactosyl-D-glucosyl side-
CC       chains in the partially completed core of lipopolysaccharide (cf.
CC       EC 2.4.1.44, EC 2.4.1.56, and EC 2.4.1.58).
//
ID   2.4.1.74
DE   Glycosaminoglycan galactosyltransferase.
CA   UDP-galactose + glycosaminoglycan = UDP + D-galactosylglycosaminoglycan.
CC   -!- Involved in the biosynthesis of galactose-containing
CC       glycosaminoglycan of Dictyostelium discoideum.
//
ID   2.4.1.75
DE   Deleted entry.
//
ID   2.4.1.76
DE   Transferred entry: 2.4.1.17.
//
ID   2.4.1.77
DE   Transferred entry: 2.4.1.17.
//
ID   2.4.1.78
DE   Phosphopolyprenol glucosyltransferase.
CA   UDP-glucose + polyprenyl phosphate = UDP + polyprenylphosphate-glucose.
CC   -!- Ficaprenyl phosphate is the best substrate; other polyprenols can
CC       also act as substrates, more slowly.
//
ID   2.4.1.79
DE   Globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase.
AN   Beta-3GalNAc-T1.
AN   Galactosylgalactosylglucosylceramide beta-D-
AN   acetylgalactosaminyltransferase.
AN   Globoside synthase.
AN   Globoside synthetase.
AN   Uridine diphosphoacetylgalactosamine-galactosylgalactosylglucosylceramide
AN   acetylgalactosaminyltransferase.
CA   UDP-N-acetyl-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D-
CA   galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide = UDP + N-acetyl-beta-
CA   D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-
CA   (1->4)-beta-D-glucosyl-(1<->1)-ceramide.
CF   Manganese.
CC   -!- Globoside is a neutral glycosphingolipid in human erythrocytes and
CC       has blood-group-P-antigen activity.
CC   -!- UDP-GalNAc is the only sugar donor that is used efficiently by the
CC       enzyme: UDP-Gal and UDP-GlcNAc result in very low enzyme activity.
CC   -!- Lactosylceramide, globoside and gangliosides GM3 and GD3 are not
CC       substrates.
DR   O75752, B3GL1_HUMAN;  Q920V1, B3GL1_MOUSE;  Q793U7, B3GL1_MUSSI;
DR   Q864U6, B3GL1_PIG  ;  Q5RAL7, B3GL1_PONAB;  Q6AY39, B3GL1_RAT  ;
//
ID   2.4.1.80
DE   Ceramide glucosyltransferase.
AN   Glucosylceramide synthase.
AN   UDP-glucose-ceramide glucosyltransferase.
CA   UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine.
CC   -!- Sphingosine and dihydrosphingosine can also act as acceptors.
CC   -!- CDP-glucose can act as donor.
DR   Q8AY29, CEGTA_XENLA;  Q5U4S8, CEGTB_XENLA;  Q16739, CEGT_HUMAN ;
DR   O88693, CEGT_MOUSE ;  Q9R0E0, CEGT_RAT   ;  Q5BL38, CEGT_XENTR ;
//
ID   2.4.1.81
DE   Flavone 7-O-beta-glucosyltransferase.
AN   UDP-glucose-apigenin beta-glucosyltransferase.
AN   UDP-glucose-luteolin beta-D-glucosyltransferase.
CA   UDP-glucose + 5,7,3',4'-tetrahydroxyflavone = UDP + 7-O-beta-D-glucosyl-
CA   5,7,3',4'-tetrahydroxyflavone.
CC   -!- A number of flavones, flavonones and flavonols can function as
CC       acceptors.
CC   -!- Different from EC 2.4.1.91.
//
ID   2.4.1.82
DE   Galactinol--sucrose galactosyltransferase.
AN   1-alpha-D-galactosyl-myo-inositol:sucrose 6-alpha-D-
AN   galactosyltransferase.
AN   Raffinose synthase.
CA   Alpha-D-galactosyl-(1->3)-1D-myo-inositol + sucrose = myo-inositol +
CA   raffinose.
CC   -!- 4-nitrophenyl-alpha-D-galactopyranoside can also act as donor.
CC   -!- Also catalyzes an exchange reaction between raffinose and sucrose
CC       (cf. EC 2.4.1.123).
DR   Q84VX0, RFS1_ARATH ;  Q94A08, RFS2_ARATH ;  Q9SYJ4, RFS4_ARATH ;
DR   Q9FND9, RFS5_ARATH ;  Q8RX87, RFS6_ARATH ;  Q5VQG4, RFS_ORYSJ  ;
DR   Q8VWN6, RFS_PEA    ;
//
ID   2.4.1.83
DE   Dolichyl-phosphate beta-D-mannosyltransferase.
AN   Dolichol-phosphate mannose synthase.
AN   Dolichol-phosphate mannosyltransferase.
AN   Mannosylphosphodolichol synthase.
AN   Mannosylphosphoryldolichol synthase.
CA   GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate.
CC   -!- Acts only on long-chain polyprenyl phosphates and alpha-
CC       dihydropolyprenyl phosphates, larger than C(35).
DR   Q1JQ93, DPM1_BOVIN ;  Q9WU83, DPM1_CRIGR ;  Q54LP3, DPM1_DICDI ;
DR   Q9VIU7, DPM1_DROME ;  O60762, DPM1_HUMAN ;  O70152, DPM1_MOUSE ;
DR   A5GFZ5, DPM1_PIG   ;  O14466, DPM1_SCHPO ;  P54856, DPM1_USTMA ;
DR   P14020, DPM1_YEAST ;
//
ID   2.4.1.84
DE   Transferred entry: 2.4.1.17.
//
ID   2.4.1.85
DE   Cyanohydrin beta-glucosyltransferase.
AN   UDP-glucose-p-hydroxymandelonitrile glucosyltransferase.
AN   UDP-glucose:(S)-4-hydroxymandelonitrile beta-D-glucosyltransferase.
AN   UDP-glucose:p-hydroxymandelonitrile-O-glucosyltransferase.
AN   UGT85B1.
AN   Uridine diphosphoglucose-cyanohydrin glucosyltransferase.
AN   Uridine diphosphoglucose-p-hydroxymandelonitrile glucosyltransferase.
AN   Uridine diphosphoglucose:aldehyde cyanohydrin beta-glucosyltransferase.
CA   UDP-D-glucose + (S)-4-hydroxymandelonitrile = UDP + (S)-4-
CA   hydroxymandelonitrile beta-D-glucoside.
CC   -!- Acts on a wide range of substrates in vitro, including cyanohydrins,
CC       terpenoids, phenolics, hexanol derivatives and plant hormones, in a
CC       regiospecific manner.
CC   -!- Involved in the biosynthesis of the cyanogenic glucoside dhurrin in
CC       sorghum, along with EC 1.14.13.41 and EC 1.14.13.68.
CC   -!- This reaction prevents the disocciation and release of toxic hydrogen
CC       cyanide.
DR   Q9SBL1, HMNGT_SORBI;
//
ID   2.4.1.86
DE   Glucosaminylgalactosylglucosylceramide beta-galactosyltransferase.
AN   Glucosaminylgalactosylglucosylceramide 4-beta-galactosyltransferase.
AN   Lactotriaosylceramide 4-beta-galactosyltransferase.
AN   Paragloboside synthase.
CA   UDP-galactose + N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-
CA   (1->4)-beta-D-glucosyl-(1<->1)-ceramide = UDP + beta-D-galactosyl-(1->3)-
CA   N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-
CA   glucosyl-(1<->1)-ceramide.
//
ID   2.4.1.87
DE   N-acetyllactosaminide 3-alpha-galactosyltransferase.
AN   Alpha-galactosyltransferase.
AN   Beta-D-galactosyl-N-acetylglucosaminylglycopeptide alpha-1,3-
AN   galactosyltransferase.
AN   Galactosyltransferase.
AN   Glucosaminylglycopeptide alpha-1,3-galactosyltransferase.
AN   N-acetyllactosaminide alpha-1,3-galactosyltransferase.
AN   UDP-Gal:Gal-beta-1->4GlcNAc-R alpha-1->3-galactosyltransferase.
AN   UDP-Gal:N-acetyllactosaminide alpha-1,3-D-galactosyltransferase.
AN   UDP-galactose-acetyllactosamine alpha-D-galactosyltransferase.
AN   UDPgalactose:beta-D-galactosyl-beta-1,4-N-acetyl-D-glucosaminyl-
AN   glycopeptide alpha-1,3-D-galactosyltransferase.
AN   Uridine diphosphogalactose-acetyllactosamine alpha-
AN   1->3-galactosyltransferase.
AN   Uridine diphosphogalactose-acetyllactosamine galactosyltransferase.
AN   Uridine diphosphogalactose-galactosylacetylglucosaminylgalactosyl-
AN   glucosylceramide galactosyltransferase.
CA   UDP-galactose + beta-D-galactosyl-(1->4)-beta-N-acetyl-D-glucosaminyl-R =
CA   UDP + alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-N-
CA   acetylglucosaminyl-R.
CC   -!- Acts on beta-galactosyl-1,4-N-acetylglucosaminyl termini on asialo-
CC       alpha(1)-acid glycoprotein and N-acetyllactosamine (beta-D-
CC       galactosyl-1,4-N-acetyl-beta-D-glucosamine), but not on
CC       2'-fucosylated-N-acetyllactosamine.
CC   -!- The non-reducing terminal N-acetyllactosamine residues of
CC       glycoproteins can also act as acceptor.
CC   -!- Now includes EC 2.4.1.124 and EC 2.4.1.151.
DR   Q3V1N9, A3LT2_MOUSE;  A0A4Z3, A3LT2_RAT  ;  A1YGR5, GGTA1_ALOCA;
DR   P14769, GGTA1_BOVIN;  Q8SQ20, GGTA1_CALJA;  Q8SPR2, GGTA1_CEBAP;
DR   Q8HY56, GGTA1_FELCA;  Q8HYB2, GGTA1_LEMCA;  A1YGR6, GGTA1_LORTA;
DR   P23336, GGTA1_MOUSE;  P50127, GGTA1_PIG  ;
//
ID   2.4.1.88
DE   Globoside alpha-N-acetylgalactosaminyltransferase.
AN   Forssman synthase.
CA   UDP-N-acetyl-D-galactosamine + N-acetyl-D-galactosaminyl-(1->3)-D-
CA   galactosyl-(1->4)-D-galactosyl-(1->4)-D-glucosyl-(1<->1)-ceramide = UDP +
CA   N-acetyl-D-galactosaminyl-(1->3)-N-acetyl-D-galactosaminyl-(1->3)-D-
CA   galactosyl-(1->4)-D-galactosyl-(1->4)-D-glucosyl-(1<->1)-ceramide.
DR   Q95158, GBGT1_CANFA;  Q8VI38, GBGT1_MOUSE;
//
ID   2.4.1.89
DE   Transferred entry: 2.4.1.69.
//
ID   2.4.1.90
DE   N-acetyllactosamine synthase.
AN   Acetyllactosamine synthetase.
AN   N-acetylglucosamine (beta-1,4)galactosyltransferase.
AN   NAL synthetase.
AN   UDP-galactose--N-acetylglucosamine beta-D-galactosyltransferase.
AN   UDP-galactose-N-acetylglucosamine beta-D-galactosyltransferase.
CA   UDP-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamine.
CC   -!- The reaction is catalyzed by a component of EC 2.4.1.22, which is
CC       identical with EC 2.4.1.38, and by an enzyme from the Golgi apparatus
CC       of animal tissues.
CC   -!- Formerly EC 2.4.1.98.
DR   P08037, B4GT1_BOVIN;  P15291, B4GT1_HUMAN;  P15535, B4GT1_MOUSE;
DR   P80225, B4GT1_RAT  ;  Q80WN9, B4GT2_CRIGR;  O60909, B4GT2_HUMAN;
DR   Q9Z2Y2, B4GT2_MOUSE;  Q5EA87, B4GT3_BOVIN;  Q80WN8, B4GT3_CRIGR;
DR   O60512, B4GT3_HUMAN;  Q91YY2, B4GT3_MOUSE;  Q5NVN3, B4GT3_PONAB;
DR   Q6P768, B4GT3_RAT  ;  Q80WN7, B4GT4_CRIGR;  O60513, B4GT4_HUMAN;
DR   Q9JJ04, B4GT4_MOUSE;  Q66HH1, B4GT4_RAT  ;
//
ID   2.4.1.91
DE   Flavonol 3-O-glucosyltransferase.
AN   UDP-glucose flavonol 3-O-glucosyltransferase.
CA   UDP-glucose + a flavonol = UDP + a flavonol 3-O-D-glucoside.
CC   -!- Acts on a variety of flavonols, including quercetin and quercetin
CC       7-O-glucoside.
CC   -!- Different from EC 2.4.1.81.
PR   PROSITE; PDOC00359;
DR   Q9LSY9, U71B1_ARATH;  O82381, U71C1_ARATH;  Q9LML6, U71C4_ARATH;
DR   O82383, U71D1_ARATH;  Q8W491, U73B3_ARATH;  Q7Y232, U73B4_ARATH;
DR   Q9ZQG4, U73B5_ARATH;  Q9LFJ8, U78D2_ARATH;  Q94AB5, U7E12_ARATH;
DR   Q9C9B0, U89B1_ARATH;
//
ID   2.4.1.92
DE   (N-acetylneuraminyl)-galactosylglucosylceramide
DE   N-acetylgalactosaminyltransferase.
AN   Asialo-GM2 synthase.
AN   Beta-1,4N-aetylgalactosaminyltransferase.
AN   GalNAc-T.
AN   Ganglioside GM2 synthase.
AN   Ganglioside GM3 acetylgalactosaminyltransferase.
AN   GM2 synthase.
AN   GM2/GD2-synthase.
AN   UDP acetylgalactosamine-(N-acetylneuraminyl)-D-galactosyl-D-
AN   glucosylceramide acetylgalactosaminyltransferase.
AN   UDP-N-acetylgalactosamine GM3 N-acetylgalactosaminyltransferase.
AN   Uridine diphosphoacetylgalactosamine-
AN   acetylneuraminylgalactosylglucosylceramide
AN   acetylgalactosaminyltransferase.
AN   Uridine diphosphoacetylgalactosamine-ganglioside GM3
AN   acetylgalactosaminyltransferase.
AN   Uridine diphosphoacetylgalactosamine-hematoside
AN   acetylgalactosaminyltransferase.
CA   UDP-N-acetyl-D-galactosamine + 1-O-(O-(N-acetyl-alpha-neuraminosyl)-
CA   (2->3)-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl)-ceramide =
CA   UDP + 1-O-(O-2-(acetylamino)-2-deoxy-beta-D-galactopyranosyl-(1->4)-O-
CA   (N-acetyl-alpha-neuraminosyl-(2->3))-O-beta-D-galactopyranosyl-(1->4)-
CA   beta-D-glucopyranosyl)-ceramide.
CC   -!- Catalyzes the formation of the gangliosides (i.e. sialic-acid-
CC       containing glycosphingolipids) GM2, GD2 and SM2 from GM3, GD3 and
CC       SM3, respectively.
CC   -!- Asialo-GM3 and lactosylceramide are also substrates,
CC       but glycoproteins and oligosaccharides are not substrates.
DR   Q00973, B4GN1_HUMAN;  Q09200, B4GN1_MOUSE;  Q10468, B4GN1_RAT  ;
//
ID   2.4.1.93
DE   Transferred entry: 4.2.2.18.
//
ID   2.4.1.94
DE   Protein N-acetylglucosaminyltransferase.
AN   N-GlcNAc transferase.
CA   UDP-N-acetyl-D-glucosamine + [protein]-L-asparagine = UDP + [protein]-
CA   N(4)-(N-acetyl-D-glucosaminyl)-L-asparagine.
CC   -!- The acceptor is the asparagine residue in a sequence of the form Asn-
CC       Xaa-(Ser/Thr).
//
ID   2.4.1.95
DE   Bilirubin-glucuronoside glucuronosyltransferase.
AN   Bilirubin monoglucuronide transglucuronidase.
CA   2 bilirubin-glucuronoside = bilirubin + bilirubin-bisglucuronoside.
//
ID   2.4.1.96
DE   sn-glycerol-3-phosphate 1-galactosyltransferase.
AN   Isofloridoside-phosphate synthase.
CA   UDP-galactose + sn-glycerol 3-phosphate = UDP + 1-O-alpha-D-galactosyl-
CA   sn-glycerol 3-phosphate.
CC   -!- The product is hydrolyzed by a phosphatase to isofloridoside, which
CC       is involved in osmoregulation (cf. EC 2.4.1.137).
//
ID   2.4.1.97
DE   1,3-beta-D-glucan phosphorylase.
AN   Laminarin phosphorylase.
CA   ((1->3)-beta-D-glucosyl)(n) + phosphate = ((1->3)-beta-D-glucosyl)(n-1) +
CA   alpha-D-glucose 1-phosphate.
CC   -!- Acts on a range of beta-1,3-oligoglucans, and on glucans of laminarin
CC       type.
CC   -!- Different from EC 2.4.1.30 and EC 2.4.1.31.
//
ID   2.4.1.98
DE   Transferred entry: 2.4.1.90.
//
ID   2.4.1.99
DE   Sucrose:sucrose fructosyltransferase.
AN   SST.
AN   Sucrose 1(F)-fructosyltransferase.
AN   Sucrose-sucrose 1-fructosyltransferase.
AN   Sucrose:sucrose 1(F)-beta-D-fructosyltransferase.
AN   Sucrose:sucrose 1-fructosyltransferase.
CA   2 sucrose = D-glucose + beta-D-fructofuranosyl-(2->1)-beta-D-
CA   fructofuranosyl alpha-D-glucopyranoside.
//
ID   2.4.1.100
DE   2,1-fructan:2,1-fructan 1-fructosyltransferase.
AN   1,2-beta-D-fructan 1(F)-fructosyltransferase.
AN   1,2-beta-D-fructan:1,2-beta-D-fructan 1(F)-beta-D-fructosyltransferase.
AN   1,2-beta-fructan 1(F)-fructosyltransferase.
AN   FFT.
AN   Fructan:fructan fructosyl transferase.
CA   (Beta-D-fructosyl-(2->1)-)(m) + (beta-D-fructosyl-(2->1)-)(n) = (beta-D-
CA   fructosyl-(2->1)-)(m-1) + (beta-D-fructosyl-(2->1)-)(n+1).
DR   P92916, GFT_ALLCE  ;
//
ID   2.4.1.101
DE   Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase.
AN   Alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase.
AN   GnTI.
AN   N-acetylglucosaminyltransferase I.
AN   N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase
AN   I.
AN   UDP-N-acetylglucosaminyl:alpha-1,3-D-mannoside-beta-1,2-N-
AN   acetylglucosaminyltransferase I.
AN   UDP-N-acetylglucosaminyl:alpha-3-D-mannoside beta-1,2-N-
AN   acetylglucosaminyltransferase I.
AN   Uridine diphosphoacetylglucosamine-alpha-1,3-mannosylglycoprotein beta-
AN   1,2-N-acetylglucosaminyltransferase.
CA   UDP-N-acetyl-D-glucosamine + 3-(alpha-D-mannosyl)-beta-D-mannosyl-R =
CA   UDP + 3-(2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl)-beta-D-
CA   mannosyl-R.
CC   -!- R represents the remainder of the N-linked oligosaccharide in the
CC       glycoprotein acceptor.
CC   -!- Note that this enzyme acts before N-acetylglucosaminyltransferases II
CC       (EC 2.4.1.143), III (EC 2.4.1.144), IV (EC 2.4.1.145),
CC       V (EC 2.4.1.155) and VI (EC 2.4.1.201).
CC   -!- Formerly EC 2.4.1.51.
DR   Q9XGM8, MGAT1_ARATH;  Q11068, MGAT1_CAEEL;  P26572, MGAT1_HUMAN;
DR   P27808, MGAT1_MOUSE;  P27115, MGAT1_RABIT;  Q09325, MGAT1_RAT  ;
//
ID   2.4.1.102
DE   Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-
DE   acetylglucosaminyltransferase.
AN   Beta(6)-N-acetylglucosaminyltransferase.
AN   O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase
AN   I.
CA   UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,3-N-acetyl-D-
CA   galactosaminyl-R = UDP + beta-D-galactosyl-1,3-(N-acetyl-beta-D-
CA   glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R.
CC   -!- Cf. EC 2.4.1.146, EC 2.4.1.147, and EC 2.4.1.148.
DR   Q92180, GCNT1_BOVIN;  Q02742, GCNT1_HUMAN;  Q09324, GCNT1_MOUSE;
DR   Q80RC7, GCNT3_BHV4 ;  Q99CW3, GCNT3_BHV4D;  Q805R1, GCNT3_BHV4L;
DR   Q9IZK2, GCNT3_BHV4V;  Q866Z5, GCNT3_BOSMU;  Q7YQE1, GCNT3_BOVIN;
DR   Q1M0V6, GCNT3_BUBBU;  O95395, GCNT3_HUMAN;  Q5JCT0, GCNT3_MOUSE;
DR   Q8CH87, GCNT3_RAT  ;  Q866Z6, GCNT3_SHEEP;  Q866Z4, GCNT3_SYNCA;
DR   Q5U258, GCNT3_XENLA;  Q71SG7, GCNT4_DANRE;  Q9P109, GCNT4_HUMAN;
//
ID   2.4.1.103
DE   Alizarin 2-beta-glucosyltransferase.
CA   UDP-glucose + alizarin = UDP + 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-
CA   anthraquinone.
CC   -!- Acts on other hydroxy- and dihydroxy-derivatives of 9,10-
CC       anthraquinone.
//
ID   2.4.1.104
DE   o-dihydroxycoumarin 7-O-glucosyltransferase.
CA   UDP-glucose + 7,8-dihydroxycoumarin = UDP + daphnin.
CC   -!- Converts the aglycone daphetin into daphnin and, more slowly,
CC       esculetin into cichoriin, umbelliferone into skimmin, hydrangetin
CC       into hydrangin and scopoletin into scopolin.
//
ID   2.4.1.105
DE   Vitexin beta-glucosyltransferase.
CA   UDP-glucose + vitexin = UDP + vitexin 2''-O-beta-D-glucoside.
CC   -!- Vitexin is a flavonoid from Cannabis sativa (hemp) and some
CC       populations of Silene alba.
//
ID   2.4.1.106
DE   Isovitexin beta-glucosyltransferase.
CA   UDP-glucose + isovitexin = UDP + isovitexin 2''-O-beta-D-glucoside.
CC   -!- Isovitexin is a flavonoid from petals of Silene alba.
//
ID   2.4.1.107
DE   Transferred entry: 2.4.1.17.
//
ID   2.4.1.108
DE   Transferred entry: 2.4.1.17.
//
ID   2.4.1.109
DE   Dolichyl-phosphate-mannose-protein mannosyltransferase.
CA   Dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-
CA   mannosylprotein.
CC   -!- Transfers mannosyl residues to the hydroxy of serine or threonine
CC       residues, producing cell-wall mannoproteins.
CC   -!- Acts only on long-chain alpha-dihydropolyprenyl derivatives, larger
CC       than C(35).
DR   O74189, PMT1_CANAL ;  O13898, PMT1_SCHPO ;  P33775, PMT1_YEAST ;
DR   Q9C100, PMT2_SCHPO ;  P31382, PMT2_YEAST ;  P47190, PMT3_YEAST ;
DR   O42933, PMT4_SCHPO ;  P46971, PMT4_YEAST ;  P52867, PMT5_YEAST ;
DR   P42934, PMT6_YEAST ;  Q06644, PMT7_YEAST ;  Q9VTK2, POMT1_DROME;
DR   Q2LZ62, POMT1_DROPS;  Q9Y6A1, POMT1_HUMAN;  Q8R2R1, POMT1_MOUSE;
DR   Q99PR0, POMT1_RAT  ;  Q9W5D4, POMT2_DROME;  Q29IL2, POMT2_DROPS;
DR   Q9UKY4, POMT2_HUMAN;  Q8BGQ4, POMT2_MOUSE;
//
ID   2.4.1.110
DE   tRNA-queuosine beta-mannosyltransferase.
CA   GDP-mannose + tRNA(Asp)-queuosine = GDP + tRNA(Asp)-O-5''-beta-D-
CA   mannosylqueuosine.
//
ID   2.4.1.111
DE   Coniferyl-alcohol glucosyltransferase.
CA   UDP-glucose + coniferyl alcohol = UDP + coniferin.
CC   -!- Sinapyl alcohol can also act as acceptor.
//
ID   2.4.1.112
DE   Transferred entry: 2.4.1.186.
//
ID   2.4.1.113
DE   Alpha-1,4-glucan-protein synthase (ADP-forming).
CA   ADP-glucose + protein = ADP + alpha-D-glucosyl-protein.
CC   -!- Builds up alpha-1,4-glucan chains covalently bound to protein, thus
CC       acting as an initiator of glycogen synthesis.
//
ID   2.4.1.114
DE   2-coumarate O-beta-glucosyltransferase.
CA   UDP-glucose + trans-2-hydroxycinnamate = UDP + trans-beta-D-glucosyl-2-
CA   hydroxycinnamate.
CC   -!- Coumarinate (cis-2-hydroxycinnamate) does not act as acceptor.
//
ID   2.4.1.115
DE   Anthocyanidin 3-O-glucosyltransferase.
AN   3-GT.
AN   UDP-glucose:anthocyanidin 3-O-D-glucosyltransferase.
AN   UDP-glucose:anthocyanidin/flavonol 3-O-glucosyltransferase.
AN   UDP-glucose:cyanidin-3-O-glucosyltransferase.
AN   Uridine diphosphoglucose-anthocyanidin 3-O-glucosyltransferase.
CA   UDP-D-glucose + an anthocyanidin = UDP + an anthocyanidin-3-O-beta-D-
CA   glucoside.
CC   -!- The anthocyanidin compounds cyanidin, delphinidin, peonidin and to a
CC       lesser extent pelargonidin can act as substrates.
CC   -!- Does not catalyze glucosylation of the 5-position of cyanidin and
CC       does not act on flavanols such as quercetin and kaempferol (cf.
CC       EC 2.4.1.91).
CC   -!- In conjunction with EC 1.14.11.19, it is involved in the conversion
CC       of leucoanthocyanidin into anthocyanidin 3-glucoside.
CC   -!- It may act on the pseudobase precursor of the anthocyanidin rather
CC       than on the anthocyanidin itself.
CC   -!- Formerly EC 2.4.1.233.
PR   PROSITE; PDOC00359;
DR   P16166, UFOG1_MAIZE;  Q40284, UFOG1_MANES;  P85358, UFOG1_TAXBA;
DR   P16165, UFOG2_MAIZE;  Q40285, UFOG2_MANES;  P16167, UFOG3_MAIZE;
DR   Q40286, UFOG4_MANES;  Q40287, UFOG5_MANES;  Q40288, UFOG6_MANES;
DR   Q40289, UFOG7_MANES;  Q96493, UFOG_GENTR ;  P14726, UFOG_HORVU ;
DR   Q43716, UFOG_PETHY ;  Q43641, UFOG_SOLME ;  P51094, UFOG_VITVI ;
//
ID   2.4.1.116
DE   Cyanidin 3-O-rutinoside 5-O-glucosyltransferase.
AN   Cyanidin-3-rhamnosylglucoside 5-O-glucosyltransferase.
AN   Uridine diphosphoglucose-cyanidin 3-rhamnosylglucoside 5-O-
AN   glucosyltransferase.
CA   UDP-glucose + cyanidin-3-O-beta-L-rhamnosyl-(1->6)-beta-D-glucoside =
CA   UDP + cyanidin 3-O-rutinoside 5-O-beta-D-glucoside.
CC   -!- Does not catalyze the glucosylation of the 5-hydroxy group of
CC       cyanidin-3-glucoside.
//
ID   2.4.1.117
DE   Dolichyl-phosphate beta-glucosyltransferase.
CA   UDP-glucose + dolichyl phosphate = UDP + dolichyl beta-D-glucosyl
CA   phosphate.
CC   -!- Solanesyl phosphate and ficaprenyl phosphate can act as acceptors,
CC       more slowly.
DR   Q54J42, ALG5_DICDI ;  Q9Y673, ALG5_HUMAN ;  Q9DB25, ALG5_MOUSE ;
DR   O60061, ALG5_SCHPO ;  P40350, ALG5_YEAST ;
//
ID   2.4.1.118
DE   Cytokinin 7-beta-glucosyltransferase.
AN   Cytokinin 7-glucosyltransferase.
AN   UDP-glucose-zeatin 7-glucosyltransferase.
AN   Uridine diphosphoglucose-zeatin 7-glucosyltransferase.
CA   UDP-glucose + N(6)-alkylaminopurine = UDP + N(6)-alkylaminopurine-7-beta-
CA   D-glucoside.
CC   -!- Acts on a range of N(6)-substituted adenines, including zeatin and
CC       N(6)-benzylaminopurine, but not N(6)-benzyladenine.
CC   -!- With some acceptors, 9-beta-D-glucosides are also formed.
//
ID   2.4.1.119
DE   Dolichyl-diphosphooligosaccharide--protein glycotransferase.
CA   Dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl
CA   diphosphate + a glycoprotein with the oligosaccharide chain attached by
CA   N-glycosyl linkage to protein L-asparagine.
CC   -!- Transfers the glucosyl-mannosyl-glucosamine polysaccharide side-
CC       chains of glycoproteins to an asparagine residue in a sequence Asn-
CC       Xaa-Ser/Thr in the nascent polypeptide chains of the protein moiety.
PR   PROSITE; PDOC00172;
DR   Q39080, DAD1_ARATH ;  Q8I7Z2, DAD1_ARAVE ;  Q5E9C2, DAD1_BOVIN ;
DR   P52872, DAD1_CAEEL ;  O13113, DAD1_CHICK ;  Q54FB6, DAD1_DICDI ;
DR   Q9VLM5, DAD1_DROME ;  P61803, DAD1_HUMAN ;  P61806, DAD1_MESAU ;
DR   P61804, DAD1_MOUSE ;  Q29036, DAD1_PIG   ;  Q5RBB4, DAD1_PONAB ;
DR   P61805, DAD1_RAT   ;  P46967, DAD1_XENLA ;  P12244, GSBP_CHICK ;
DR   Q54C27, OST1_DICDI ;  Q10176, OST1_SCHPO ;  P41543, OST1_YEAST ;
DR   O14238, OST2_SCHPO ;  P46964, OST2_YEAST ;  P48439, OST3_YEAST ;
DR   A6QPY0, OST48_BOVIN;  P45971, OST48_CAEEL;  Q05052, OST48_CANFA;
DR   P48440, OST48_CHICK;  Q6NYS8, OST48_DANRE;  Q54E62, OST48_DICDI;
DR   Q24319, OST48_DROME;  P39656, OST48_HUMAN;  O54734, OST48_MOUSE;
DR   Q29381, OST48_PIG  ;  Q5R501, OST48_PONAB;  Q641Y0, OST48_RAT  ;
DR   Q6GNR9, OST48_XENLA;  B1H3C9, OST48_XENTR;  Q99380, OST4_YEAST ;
DR   Q92316, OST5_YEAST ;  Q03723, OST6_YEAST ;  O59866, OSTB_SCHPO ;
DR   P33767, OSTB_YEAST ;  Q02795, OSTD_YEAST ;  P80896, RPN1_CHICK ;
DR   P04843, RPN1_HUMAN ;  Q4R4T0, RPN1_MACFA ;  Q91YQ5, RPN1_MOUSE ;
DR   Q9GMB0, RPN1_PIG   ;  Q5RFB6, RPN1_PONAB ;  P07153, RPN1_RAT   ;
DR   Q3SZI6, RPN2_BOVIN ;  P80897, RPN2_CHICK ;  Q54HG9, RPN2_DICDI ;
DR   P04844, RPN2_HUMAN ;  Q9DBG6, RPN2_MOUSE ;  Q9GL01, RPN2_PIG   ;
DR   Q5RBM1, RPN2_PONAB ;  P25235, RPN2_RAT   ;  Q2KJI2, STT3A_BOVIN;
DR   P46977, STT3A_HUMAN;  P46978, STT3A_MOUSE;  Q5RCE2, STT3A_PONAB;
DR   Q8TCJ2, STT3B_HUMAN;  Q3TDQ1, STT3B_MOUSE;  Q54NM9, STT3_DICDI ;
DR   O94335, STT3_SCHPO ;  P39007, STT3_YEAST ;
//
ID   2.4.1.120
DE   Sinapate 1-glucosyltransferase.
CA   UDP-glucose + sinapate = UDP + 1-sinapoyl-D-glucose.
CC   -!- Some other hydroxycinnamates, including 4-coumarate, ferulate and
CC       caffeate, can also act as acceptors, more slowly.
CC   -!- Only glucose esters, not glucosides, are formed (cf. EC 2.4.1.126).
DR   Q9LVF0, U84A2_ARATH;
//
ID   2.4.1.121
DE   Indole-3-acetate beta-glucosyltransferase.
AN   IAA-Glu synthetase.
CA   UDP-glucose + (indol-3-yl)acetate = UDP + 1-O-(indol-3-yl)acetyl-beta-D-
CA   glucose.
DR   Q41819, IABG_MAIZE ;  Q9LR44, U75B1_ARATH;  Q9ZVY5, U75B2_ARATH;
//
ID   2.4.1.122
DE   Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase.
CA   UDP-galactose + glycoprotein N-acetyl-D-galactosamine = UDP +
CA   glycoprotein D-galactosyl-1,3-N-acetyl-D-galactosamine.
CC   -!- The non-reducing O-serine-linked N-acetylgalactosamine residues in
CC       mucin glycoproteins can act as acceptors.
DR   Q0VC84, C1GLT_BOVIN;  Q18515, C1GLT_CAEEL;  Q5F3G7, C1GLT_CHICK;
DR   Q7K237, C1GLT_DROME;  Q9NS00, C1GLT_HUMAN;  Q9JJ06, C1GLT_MOUSE;
DR   Q9JJ05, C1GLT_RAT  ;  Q6GNL1, C1GLT_XENLA;  Q08BL3, C1GTA_DANRE;
DR   Q7SYI5, C1GTB_DANRE;
//
ID   2.4.1.123
DE   Inositol 3-alpha-galactosyltransferase.
AN   Galactinol synthase.
AN   Inositol 1-alpha-galactosyltransferase.
AN   UDP-galactose:myo-inositol 3-alpha-D-galactosyltransferase.
CA   UDP-galactose + myo-inositol = UDP + O-alpha-D-galactosyl-(1->3)-1D-myo-
CA   inositol.
CC   -!- An enzyme from plants involved in the formation of raffinose and
CC       stachyose (cf. EC 2.4.1.67 and EC 2.4.1.82).
//
ID   2.4.1.124
DE   Transferred entry: 2.4.1.87.
//
ID   2.4.1.125
DE   Sucrose--1,6-alpha-glucan 3(6)-alpha-glucosyltransferase.
AN   Water-soluble-glucan synthase.
CA   Sucrose + (1,6-alpha-D-glucosyl)(n) = D-fructose + (1,6-alpha-D-
CA   glucosyl)(n+1).
CC   -!- Also transfers glucosyl residues to the 3-position on glucose
CC       residues in glucans, producing a highly-branched 1,6-alpha-D-glucan.
//
ID   2.4.1.126
DE   Hydroxycinnamate 4-beta-glucosyltransferase.
CA   UDP-glucose + trans-4-hydroxycinnamate = UDP + 4-O-beta-D-glucosyl-4-
CA   hydroxycinnamate.
CC   -!- Acts on 4-coumarate, ferulate, caffeate and sinapate, forming a
CC       mixture of 4-glucosides and glucose esters (cf. EC 2.4.1.120).
DR   Q9LVR1, U72E2_ARATH;  O81498, U72E3_ARATH;  Q5XF20, U84A1_ARATH;
DR   O23401, U84A3_ARATH;  O23402, U84A4_ARATH;
//
ID   2.4.1.127
DE   Monoterpenol beta-glucosyltransferase.
CA   UDP-glucose + (-)-menthol = UDP + (-)-menthyl O-beta-D-glucoside.
CC   -!- (+)-neomenthol can also act as acceptor.
//
ID   2.4.1.128
DE   Scopoletin glucosyltransferase.
CA   UDP-glucose + scopoletin = UDP + scopolin.
//
ID   2.4.1.129
DE   Peptidoglycan glycosyltransferase.
AN   Bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-
AN   pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-
AN   glucosaminyltransferase.
AN   Penicillin binding protein (3 or 1B).
AN   Peptidoglycan TGase.
AN   Peptidoglycan transglycosylase.
AN   PG-II.
CA   (GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala))(n)-
CA   diphosphoundecaprenol + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-
CA   D-Ala-D-Ala)-diphosphoundecaprenol = (GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-
CA   gamma-D-Glu-L-Lys-D-Ala-D-Ala))(n+1)-diphosphoundecaprenol + undecaprenyl
CA   diphosphate.
CC   -!- The enzyme also works when the lysine residue is replaced by meso-
CC       2,6-diaminoheptanedioate (meso-2,6-diaminopimelate, A2pm) combined
CC       with adjacent residues through its L-center, as it is in Gram-
CC       negative and some Gram-positive organisms.
CC   -!- The undecaprenol involved is ditrans,octacis-undecaprenol.
CC   -!- Involved in the synthesis of cell-wall peptidoglycan.
DR   P57317, FTSI_BUCAI ;  O85297, FTSI_BUCAP ;  Q89AQ0, FTSI_BUCBP ;
DR   A2CI41, FTSI_CHLAT ;  P0AD69, FTSI_ECO57 ;  P0AD68, FTSI_ECOLI ;
DR   P45059, FTSI_HAEIN ;  Q9MUV9, FTSI_MESVI ;  Q9TL36, FTSI_NEPOL ;
DR   P57296, PBPB_BUCAI ;  Q89AR2, PBPB_BUCBP ;  P02919, PBPB_ECOLI ;
DR   P45345, PBPB_HAEIN ;  Q9KUC0, PBPB_VIBCH ;
//
ID   2.4.1.130
DE   Transferred entry: 2.4.1.258, 2.4.1.259, 2.4.1.260 and 2.4.1.261.
//
ID   2.4.1.131
DE   GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase.
CA   2 GDP-D-mannose + D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-beta-
CA   (1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol = 2 GDP + D-Man-
CA   alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-
CA   D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol.
CC   -!- The biosynthesis of asparagine-linked glycoproteins (N-linked protein
CC       glycosylation) utilizes a dolichyl diphosphate-linked glycosyl donor,
CC       which is assembled by the series of membrane-bound
CC       glycosyltransferases that comprise the dolichol pathway.
CC   -!- ALG11 mannosyltransferase from Saccharomyces cerevisiae carries out
CC       two sequential steps in the formation of the lipid-linked core
CC       oligosaccharide, adding two mannose residues in alpha(1->2) linkages
CC       to the nascent oligosaccharide.
CC   -!- Formerly EC 2.4.1.n4.
DR   Q9XEE9, ALG11_ARATH;  Q75B12, ALG11_ASHGO;  Q59S72, ALG11_CANAL;
DR   Q6FWD1, ALG11_CANGA;  Q7ZW24, ALG11_DANRE;  Q6BVB2, ALG11_DEBHA;
DR   Q54DM9, ALG11_DICDI;  Q2TAA5, ALG11_HUMAN;  Q6CLD6, ALG11_KLULA;
DR   Q3TZM9, ALG11_MOUSE;  Q8X092, ALG11_NEUCR;  Q5R7Z6, ALG11_PONAB;
DR   O74878, ALG11_SCHPO;  Q08B22, ALG11_XENLA;  Q6P312, ALG11_XENTR;
DR   Q6C9T3, ALG11_YARLI;  P53954, ALG11_YEAST;
//
ID   2.4.1.132
DE   GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase.
AN   Mannosyltransferase II.
CA   GDP-D-mannose + D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-
CA   diphosphodolichol = GDP + D-Man-alpha-(1->3)-D-Man-beta-(1->4)-D-GlcNAc-
CA   beta-(1->4)-GlcNAc-diphosphodolichol.
CC   -!- The biosynthesis of asparagine-linked glycoproteins utilizes a
CC       dolichyl diphosphate-linked glycosyl donor, which is assembled by the
CC       series of membrane-bound glycosyltransferases that comprise the
CC       dolichol pathway.
CC   -!- Alg2 mannosyltransferase from Saccharomyces cerevisiae carries out an
CC       alpha-1,3-mannosylation of D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-
CC       GlcNAc-diphosphodolichol, followed by an alpha-1,6-mannosylation (cf.
CC       EC 2.4.1.257), to form the first branched pentasaccharide
CC       intermediate of the dolichol pathway.
DR   Q755C1, ALG2_ASHGO ;  Q59LF2, ALG2_CANAL ;  Q6FJJ9, ALG2_CANGA ;
DR   Q6BVA4, ALG2_DEBHA ;  Q7KWM5, ALG2_DICDI ;  Q9H553, ALG2_HUMAN ;
DR   Q6CWQ0, ALG2_KLULA ;  Q9DBE8, ALG2_MOUSE ;  Q8X0H8, ALG2_NEUCR ;
DR   O94738, ALG2_RHIPU ;  Q96WW6, ALG2_SCHPO ;  Q6C3V7, ALG2_YARLI ;
DR   P43636, ALG2_YEAST ;
//
ID   2.4.1.133
DE   Xylosylprotein 4-beta-galactosyltransferase.
AN   Galactosyltransferase I.
AN   UDP-D-galactose:D-xylose galactosyltransferase.
AN   UDP-D-galactose:xylose galactosyltransferase.
AN   Uridine diphosphogalactose-xylose galactosyltransferase.
CA   UDP-galactose + O-beta-D-xylosylprotein = UDP + 4-beta-D-galactosyl-O-
CA   beta-D-xylosylprotein.
CF   Manganese.
CC   -!- Involved in the biosynthesis of the linkage region of
CC       glycosaminoglycan chains as part of proteoglycan biosynthesis
CC       (chondroitin, dermatan and heparan sulfates).
DR   Q9UBV7, B4GT7_HUMAN;  Q8R087, B4GT7_MOUSE;
//
ID   2.4.1.134
DE   Galactosylxylosylprotein 3-beta-galactosyltransferase.
AN   Galactosyltransferase II.
AN   Uridine diphosphogalactose-galactosylxylose galactosyltransferase.
CA   UDP-galactose + 4-beta-D-galactosyl-O-beta-D-xylosylprotein = UDP +
CA   3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein.
CF   Manganese.
CC   -!- Involved in the biosynthesis of the linkage region of
CC       glycosaminoglycan chains as part of proteoglycan biosynthesis
CC       (chondroitin, dermatan and heparan sulfates).
DR   Q96L58, B3GT6_HUMAN;  Q91Z92, B3GT6_MOUSE;  Q9USX0, PVG3_SCHPO ;
DR   Q9N491, SQV2_CAEEL ;
//
ID   2.4.1.135
DE   Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase.
AN   Glucuronosyltransferase I.
AN   Uridine diphosphate glucuronic acid:acceptor glucuronosyltransferase.
CA   UDP-glucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-
CA   xylosylprotein = UDP + 3-beta-D-glucuronosyl-3-beta-D-galactosyl-4-beta-
CA   D-galactosyl-O-beta-D-xylosylprotein.
CF   Manganese.
CC   -!- Involved in the biosynthesis of the linkage region of
CC       glycosaminoglycan chains as part of proteoglycan biosynthesis
CC       (chondroitin, dermatan and heparan sulfates).
DR   Q9VTG7, B3G2P_DROME;  Q9VLA1, B3G2S_DROME;  Q5CB03, B3GA1_CANFA;
DR   Q9P2W7, B3GA1_HUMAN;  Q9CW73, B3GA1_MOUSE;  Q5CB04, B3GA1_PANTR;
DR   O35789, B3GA1_RAT  ;  Q5CAZ6, B3GA2_CANFA;  Q9NPZ5, B3GA2_HUMAN;
DR   P59270, B3GA2_MOUSE;  Q9Z137, B3GA2_RAT  ;  Q9WU47, B3GA3_CRIGR;
DR   O94766, B3GA3_HUMAN;  P58158, B3GA3_MOUSE;  O97422, B3GI_DROME ;
DR   Q09363, SQV8_CAEEL ;
//
ID   2.4.1.136
DE   Gallate 1-beta-glucosyltransferase.
AN   UDP-glucose--vanillate 1-glucosyltransferase.
CA   UDP-glucose + gallate = UDP + 1-galloyl-beta-D-glucose.
CC   -!- A number of substituted benzoic acids and, more slowly, cinnamic
CC       acids, can act as acceptors.
CC   -!- Vanillin is the best acceptor investigated.
//
ID   2.4.1.137
DE   sn-glycerol-3-phosphate 2-alpha-galactosyltransferase.
AN   Floridoside-phosphate synthase.
CA   UDP-galactose + sn-glycerol 3-phosphate = UDP + 2-(alpha-D-galactosyl)-
CA   sn-glycerol 3-phosphate.
CC   -!- The product is hydrolyzed by a phosphatase to floridoside (cf.
CC       EC 2.4.1.96).
//
ID   2.4.1.138
DE   Mannotetraose 2-alpha-N-acetylglucosaminyltransferase.
AN   Alpha-N-acetylglucosaminyltransferase.
CA   UDP-N-acetyl-D-glucosamine + (1->3)-alpha-D-mannosyl-(1->2)-alpha-D-
CA   mannosyl-(1->2)-alpha-D-mannosyl-D-mannose = UDP + (1->3)-alpha-D-
CA   mannosyl-(1->2)-(N-acetyl-alpha-D-glucosaminyl-alpha-D-mannosyl)-(1->2)-
CA   alpha-D-mannosyl-D-mannose.
//
ID   2.4.1.139
DE   Maltose synthase.
CA   2 alpha-D-glucose 1-phosphate + H(2)O = maltose + 2 phosphate.
CC   -!- Neither free phosphate nor maltose 1-phosphate is an intermediate in
CC       the reaction.
//
ID   2.4.1.140
DE   Alternansucrase.
AN   Sucrose-1,6(3)-alpha-glucan 6(3)-alpha-glucosyltransferase.
AN   Sucrose:1,6-, 1,3-alpha-D-glucan 3-alpha- and 6-alpha-D-
AN   glucosyltransferase.
CA   Transfers alternately an alpha-D-glucosyl residue from sucrose to the
CA   6-position and the 3-position of the non-reducing terminal residue of an
CA   alpha-D-glucan, thus producing a glucan having alternating alpha-(1->6)-
CA   and alpha-(1->3)-linkages.
CC   -!- The product, which has quite different properties from other
CC       dextrans, has been called alternan.
//
ID   2.4.1.141
DE   N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase.
CA   UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol =
CA   UDP + N,N'-diacetylchitobiosyl-diphosphodolichol.
DR   Q750J3, ALG13_ASHGO;  Q4WQN1, ALG13_ASPFU;  Q5ABE5, ALG13_CANAL;
DR   Q6FVR6, ALG13_CANGA;  P0CN89, ALG13_CRYNB;  P0CN88, ALG13_CRYNJ;
DR   Q6BST1, ALG13_DEBHA;  Q9NP73, ALG13_HUMAN;  Q6CXY0, ALG13_KLULA;
DR   Q9D8C3, ALG13_MOUSE;  Q5I0K7, ALG13_RAT  ;  O14190, ALG13_SCHPO;
DR   Q6C3P1, ALG13_YARLI;  P53178, ALG13_YEAST;
//
ID   2.4.1.142
DE   Chitobiosyldiphosphodolichol beta-mannosyltransferase.
AN   GDP-mannose-dolichol diphosphochitobiose mannosyltransferase.
AN   Guanosine diphosphomannose-dolichol diphosphochitobiose
AN   mannosyltransferase.
CA   GDP-mannose + chitobiosyldiphosphodolichol = GDP + beta-1,4-D-
CA   mannosylchitobiosyldiphosphodolichol.
DR   Q75BA5, ALG1_ASHGO ;  Q59Q79, ALG1_CANAL ;  Q6FLZ2, ALG1_CANGA ;
DR   Q6BS98, ALG1_DEBHA ;  P90522, ALG1_DICDI ;  Q9BT22, ALG1_HUMAN ;
DR   Q6CVU2, ALG1_KLULA ;  Q921Q3, ALG1_MOUSE ;  Q5R7A2, ALG1_PONAB ;
DR   O13933, ALG1_SCHPO ;  Q6C3K2, ALG1_YARLI ;  P16661, ALG1_YEAST ;
//
ID   2.4.1.143
DE   Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase.
AN   Acetylglucosaminyltransferase II.
AN   Alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase.
AN   GnTII.
AN   N-acetylglucosaminyltransferase II.
AN   N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase
AN   II.
AN   UDP-GlcNAc:mannoside alpha-1-6 acetylglucosaminyltransferase.
AN   Uridine diphosphoacetylglucosamine-alpha-1,6-mannosylglycoprotein beta-1-
AN   2-N-acetylglucosaminyltransferase.
AN   Uridine diphosphoacetylglucosamine-alpha-D-mannoside beta-1-
AN   2-acetylglucosaminyltransferase.
AN   Uridine diphosphoacetylglucosamine-mannoside alpha-
AN   1->6-acetylglucosaminyltransferase.
CA   UDP-N-acetyl-D-glucosamine + 6-(alpha-D-mannosyl)-beta-D-mannosyl-R =
CA   UDP + 6-(2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl)-beta-D-
CA   mannosyl-R.
CC   -!- R represents the remainder of the N-linked oligosaccharide in the
CC       glycoprotein acceptor.
CC   -!- Note that this enzyme acts after N-acetylglucosaminyltransferase I
CC       (EC 2.4.1.101) but before N-acetylglucosaminyltransferases III
CC       (EC 2.4.1.144), IV (EC 2.4.1.145), V (EC 2.4.1.155) and VI
CC       (EC 2.4.1.201).
CC   -!- Formerly EC 2.4.1.51.
DR   Q10469, MGAT2_HUMAN;  Q921V5, MGAT2_MOUSE;  O19071, MGAT2_PIG  ;
DR   Q09326, MGAT2_RAT  ;
//
ID   2.4.1.144
DE   Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase.
AN   Beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase.
AN   GnTIII.
AN   N-acetylglucosaminyltransferase III.
AN   N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase
AN   III.
AN   Uridine diphosphoacetylglucosamine-glycopeptide beta-4-
AN   acetylglucosaminyltransferase III.
CA   UDP-N-acetyl-D-glucosamine + beta-D-mannosyl-R = UDP + 4-(N-acetyl-beta-
CA   D-glucosaminyl)-beta-D-mannosyl-R.
CC   -!- R represents the remainder of the N-linked oligosaccharide in the
CC       glycoprotein acceptor.
CC   -!- The action of this enzyme probably prevents further attachment of
CC       N-acetylglucosamine residues to the growing carbohydrate chain.
CC   -!- Formerly EC 2.4.1.51.
DR   Q09327, MGAT3_HUMAN;  Q10470, MGAT3_MOUSE;  Q02527, MGAT3_RAT  ;
//
ID   2.4.1.145
DE   Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase.
AN   Alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase.
AN   Beta-acetylglucosaminyltransferase IV.
AN   GnTIV.
AN   N-acetylglucosaminyltransferase IV.
AN   N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase
AN   IV.
AN   Uridine diphosphoacetylglucosamine-glycopeptide beta-4-
AN   acetylglucosaminyltransferase IV.
CA   UDP-N-acetyl-D-glucosamine + 3-(2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-
CA   mannosyl)-beta-D-mannosyl-R = UDP + 3-(2,4-bis(N-acetyl-beta-D-
CA   glucosaminyl)-alpha-D-mannosyl)-beta-D-mannosyl-R.
CC   -!- R represents the remainder of the N-linked oligosaccharide in the
CC       glycoprotein acceptor.
CC   -!- The best acceptor for this enzyme is probably the same as that
CC       favored by EC 2.4.1.144.
CC   -!- Formerly EC 2.4.1.51.
DR   O77836, MGT4A_BOVIN;  Q5F407, MGT4A_CHICK;  Q9UM21, MGT4A_HUMAN;
DR   Q4R854, MGT4A_MACFA;  Q812G0, MGT4A_MOUSE;  Q5REP8, MGT4A_PONAB;
DR   Q5M854, MGT4A_RAT  ;  Q6GQI7, MGT4A_XENLA;  A4IID1, MGT4A_XENTR;
DR   Q6GMK0, MGT4B_DANRE;  Q9UQ53, MGT4B_HUMAN;  Q812F8, MGT4B_MOUSE;
DR   Q9DGD1, MGT4C_CHICK;  Q5U3T0, MGT4C_DANRE;  Q9UBM8, MGT4C_HUMAN;
DR   Q4R4A8, MGT4C_MACFA;  Q9D306, MGT4C_MOUSE;  Q6ITT3, MGT4C_PIG  ;
//
ID   2.4.1.146
DE   Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-
DE   acetylglucosaminyltransferase.
AN   Elongation 3-beta-GalNAc-transferase.
AN   O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase
AN   II.
CA   UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->3)-(N-acetyl-D-
CA   glucosaminyl-(1->6))-N-acetyl-D-galactosaminyl-R = UDP + N-acetyl-beta-D-
CA   glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-(N-acetyl-D-glucosaminyl-
CA   (1->6))-N-acetyl-D-galactosaminyl-R.
CC   -!- Cf. EC 2.4.1.102, EC 2.4.1.147, and EC 2.4.1.148.
//
ID   2.4.1.147
DE   Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-
DE   acetylglucosaminyltransferase.
AN   Core 3-beta-GlcNAc-transferase.
AN   O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase
AN   III.
CA   UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-galactosaminyl-R = UDP +
CA   N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-D-galactosaminyl-R.
CC   -!- Cf. EC 2.4.1.102, EC 2.4.1.146, and EC 2.4.1.148.
//
ID   2.4.1.148
DE   Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-
DE   acetylglucosaminyltransferase.
AN   Core 6-beta-GalNAc-transferase B.
AN   O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase
AN   IV.
CA   UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-glucosaminyl-(1->3)-N-
CA   acetyl-D-galactosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-(1->6)-
CA   (N-acetyl-beta-D-glucosaminyl-(1->3))-N-acetyl-D-galactosaminyl-R.
CC   -!- Cf. EC 2.4.1.102, EC 2.4.1.146, and EC 2.4.1.147.
//
ID   2.4.1.149
DE   N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase.
AN   GnTE.
AN   Poly-N-acetyllactosamine extension enzyme.
CA   UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->4)-N-acetyl-D-
CA   glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-
CA   galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R.
CC   -!- Acts on beta-galactosyl-1,4-N-acetylglucosaminyl termini on asialo-
CC       alpha(1)-acid glycoprotein and other glycoproteins and
CC       oligosaccharides.
DR   Q5EA01, B3GN1_BOVIN;  O43505, B3GN1_HUMAN;  Q8BWP8, B3GN1_MOUSE;
DR   Q5R4S2, B3GN1_PONAB;
//
ID   2.4.1.150
DE   N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase.
AN   N-acetylglucosaminyltransferase.
CA   UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-
CA   glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,6-beta-D-
CA   galactosyl-1,4-N-acetyl-D-glucosaminyl-R.
CC   -!- Acts on beta-galactosyl-1,4-N-acetylglucosaminyl termini on asialo-
CC       alpha(1)-acid glycoprotein.
DR   P97402, GCNT2_MOUSE;  Q80RC7, GCNT3_BHV4 ;  Q99CW3, GCNT3_BHV4D;
DR   Q805R1, GCNT3_BHV4L;  Q9IZK2, GCNT3_BHV4V;  Q866Z5, GCNT3_BOSMU;
DR   Q7YQE1, GCNT3_BOVIN;  Q1M0V6, GCNT3_BUBBU;  O95395, GCNT3_HUMAN;
DR   Q5JCT0, GCNT3_MOUSE;  Q8CH87, GCNT3_RAT  ;  Q866Z6, GCNT3_SHEEP;
DR   Q866Z4, GCNT3_SYNCA;  Q5U258, GCNT3_XENLA;  Q8N0V5, GNT2A_HUMAN;
DR   Q06430, GNT2B_HUMAN;  Q8NFS9, GNT2C_HUMAN;
//
ID   2.4.1.151
DE   Transferred entry: 2.4.1.87.
//
ID   2.4.1.152
DE   4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase.
AN   Galactoside 3-fucosyltransferase.
AN   GDP-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-
AN   fucosyltransferase.
AN   Guanosine diphosphofucose-glucoside alpha-1->3-fucosyltransferase.
AN   Lewis-negative alpha-3-fucosyltransferase.
AN   Plasma alpha-3-fucosyltransferase.
CA   GDP-beta-L-fucose + (1->4)-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R =
CA   GDP + (1->4)-beta-D-galactosyl-(alpha-(1->3)-L-fucosyl)-N-acetyl-D-
CA   glucosaminyl-R.
CC   -!- Normally acts on a glycoconjugate where R (see CA line) is a
CC       glycoprotein or glycolipid.
CC   -!- This enzyme fucosylates on O-3 of an N-acetylglucosamine that carries
CC       a galactosyl group on O-4, unlike EC 2.4.1.65, which fucosylates on
CC       O-4 of an N-acetylglucosamine that carries a galactosyl group on O-3.
//
ID   2.4.1.153
DE   Dolichyl-phosphate alpha-N-acetylglucosaminyltransferase.
AN   Dolichyl-phosphate acetylglucosaminyltransferase.
AN   Dolichyl-phosphate N-acetylglucosaminyltransferase.
CA   UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UDP + dolichyl
CA   N-acetyl-alpha-D-glucosaminyl phosphate.
//
ID   2.4.1.154
DE   Deleted entry.
//
ID   2.4.1.155
DE   Alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase.
AN   Alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-
AN   acetylglucosaminyltransferase.
AN   Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase.
AN   GnTV.
AN   N-acetylglucosaminyltransferase V.
AN   UDP-N-acetylglucosamine:alpha-mannoside-beta-1,6
AN   N-acetylglucosaminyltransferase.
AN   Uridine diphosphoacetylglucosamine-alpha-mannoside beta-
AN   1->6-acetylglucosaminyltransferase.
CA   UDP-N-acetyl-D-glucosamine + 6-(2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-
CA   mannosyl)-beta-D-mannosyl-R = UDP + 6-(2,6-bis(N-acetyl-beta-D-
CA   glucosaminyl)-alpha-D-mannosyl)-beta-D-mannosyl-R.
CC   -!- R represents the remainder of the N-linked oligosaccharide in the
CC       glycoprotein acceptor.
DR   Q9NDH7, GLY2_CAEEL ;  P97259, MGT5A_CRIGR;  Q09328, MGT5A_HUMAN;
DR   Q8R4G6, MGT5A_MOUSE;  Q08834, MGT5A_RAT  ;  Q3V5L5, MGT5B_HUMAN;
DR   Q765H6, MGT5B_MOUSE;
//
ID   2.4.1.156
DE   Indolylacetyl-myo-inositol galactosyltransferase.
AN   Indol-3-ylacetyl-myo-inositol galactoside synthase.
AN   Uridine diphosphogalactose-indolylacetylinositol galactosyltransferase.
CA   UDP-galactose + (indol-3-yl)acetyl-myo-inositol = UDP + 5-O-(indol-3-
CA   yl)acetyl-myo-inositol D-galactoside.
//
ID   2.4.1.157
DE   1,2-diacylglycerol 3-glucosyltransferase.
AN   UDP-glucose-diacylglycerol glucosyltransferase.
CA   UDP-glucose + 1,2-diacyl-sn-glycerol = UDP + 3-D-glucosyl-1,2-diacyl-
CA   sn-glycerol.
CC   -!- Many diacylglycerols with long-chain acyl groups can act as
CC       acceptors.
//
ID   2.4.1.158
DE   13-hydroxydocosanoate 13-beta-glucosyltransferase.
AN   13-glucosyloxydocosanoate 2'-beta-glucosyltransferase.
AN   UDP-glucose-13-hydroxydocosanoate glucosyltransferase.
CA   UDP-glucose + 13-hydroxydocosanoate = UDP + 13-beta-D-
CA   glucosyloxydocosanoate.
CC   -!- 13-beta-D-glucosyloxydocosanoate can also act as acceptor, leading to
CC       the formation by Candida bogoriensis of the extracellular glycolipid,
CC       hydroxydocosanoate sophoroside diacetate.
//
ID   2.4.1.159
DE   Flavonol-3-O-glucoside L-rhamnosyltransferase.
AN   UDP-rhamnose:flavonol 3-O-glucoside rhamnosyltransferase.
AN   Uridine diphosphorhamnose-flavonol 3-O-glucoside rhamnosyltransferase.
CA   UDP-L-rhamnose + a flavonol 3-O-D-glucoside = UDP + a flavonol 3-O-(beta-
CA   L-rhamnosyl-(1->6)-beta-D-glucoside).
CC   -!- Converts flavonol 3-O-glucosides to 3-O-rutinosides.
CC   -!- Also acts, more slowly, on rutin, quercetin 3-O-galactoside and
CC       flavonol 3-O-rhamnosides.
DR   Q9S9P6, U78D1_ARATH;
//
ID   2.4.1.160
DE   Pyridoxine 5'-O-beta-D-glucosyltransferase.
AN   UDP-glucose-pyridoxine glucosyltransferase.
CA   UDP-glucose + pyridoxine = UDP + 5'-O-beta-D-glucosylpyridoxine.
CC   -!- 4'-deoxypyridoxine and pyridoxamine can also act as acceptors, more
CC       slowly.
//
ID   2.4.1.161
DE   Oligosaccharide 4-alpha-D-glucosyltransferase.
AN   Amylase III.
CA   Transfers the non-reducing terminal alpha-D-glucose residue from a
CA   (1->4)-alpha-D-glucan to the 4-position of an alpha-D-glucan, thus
CA   bringing about the hydrolysis of oligosaccharides.
CC   -!- Acts on amylose, amylopectin, glycogen and maltooligosaccharides,
CC       but not on maltose.
CC   -!- No detectable free glucose is formed.
//
ID   2.4.1.162
DE   Aldose beta-D-fructosyltransferase.
CA   Alpha-D-aldosyl(1) beta-D-fructoside + D-aldose(2) = D-aldose(1) + alpha-
CA   D-aldosyl(2) beta-D-fructoside.
//
ID   2.4.1.163
DE   Beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-
DE   acetylglucosaminyltransferase.
AN   Poly-N-acetyllactosamine extension enzyme.
CA   UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-
CA   glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-
CA   ceramide = UDP + N-acetyl-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-
CA   N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-
CA   glucosyl-(1<->1)-ceramide.
CF   Manganese.
//
ID   2.4.1.164
DE   Galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,6-N-
DE   acetylglucosaminyltransferase.
CA   UDP-N-acetyl-D-glucosamine + D-galactosyl-(1->4)-N-acetyl-beta-D-
CA   glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-
CA   ceramide = UDP + N-acetyl-D-glucosaminyl-(1->6)-beta-D-galactosyl-(1->4)-
CA   N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-
CA   glucosyl-(1<->1)-ceramide.
CF   Manganese.
//
ID   2.4.1.165
DE   N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-
DE   acetylgalactosaminyltransferase.
CA   UDP-N-acetyl-D-galactosamine + N-acetylneuraminyl-(2->3)-alpha-D-
CA   galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide = UDP + N-acetyl-D-
CA   galactosaminyl-(1->4)-beta-N-acetylneuraminyl-(2->3)-alpha-D-galactosyl-
CA   (1->4)-beta-D-glucosyl-(1<->1)-ceramide.
CF   Manganese.
CC   -!- Only substances containing sialic acid residues can act as acceptors;
CC       bovine fetuin is the best acceptor tested.
//
ID   2.4.1.166
DE   Raffinose--raffinose alpha-galactosyltransferase.
CA   2 raffinose = 1(F)-alpha-D-galactosylraffinose + sucrose.
CC   -!- The 3(F) position of raffinose can also act as galactosyl acceptor.
CC   -!- Involved in the accumulation of the tetrasaccharides lychnose and
CC       isolychnose in the leaves of Cerastium arvense and other plants of
CC       the family Caryophyllaceae during late autumn.
//
ID   2.4.1.167
DE   Sucrose 6(F)-alpha-galactosyltransferase.
CA   UDP-galactose + sucrose = UDP + 6(F)-alpha-D-galactosylsucrose.
CC   -!- Involved in the synthesis of the trisaccharide planteose and higher
CC       analogs in the seeds of Plantago and Sesamum species.
//
ID   2.4.1.168
DE   Xyloglucan 4-glucosyltransferase.
CA   Transfers a beta-D-glucosyl residue from UDP-glucose on to a glucose
CA   residue in xyloglucan, forming a beta-(1->4)-D-glucosyl-D-glucose
CA   linkage.
CC   -!- In association with EC 2.4.2.39, brings about the synthesis of
CC       xyloglucan.
CC   -!- Concurrent transfers of glucose and xylose are essential for this
CC       synthesis.
CC   -!- Not identical with EC 2.4.1.12.
//
ID   2.4.1.169
DE   Transferred entry: 2.4.2.39.
//
ID   2.4.1.170
DE   Isoflavone 7-O-glucosyltransferase.
CA   UDP-glucose + an isoflavone = UDP + an isoflavone 7-O-beta-D-glucoside.
CC   -!- The 4'-methoxy isoflavones biochanin A and formononetin and, more
CC       slowly, the 4'-hydroxy isoflavones genistein and daidzein, can act as
CC       acceptors.
CC   -!- The enzyme does not act on isoflavanones, flavones, flavanones,
CC       flavanols or coumarins.
//
ID   2.4.1.171
DE   Methyl-ONN-azoxymethanol beta-D-glucosyltransferase.
AN   Cycasin synthase.
CA   UDP-glucose + CH(3)-N(O)=N-CH(2)OH = UDP + cycasin.
CC   -!- Brings about the biosynthesis of the toxic substance cycasin in the
CC       leaves of Japanese cycad, Cycas revoluta.
//
ID   2.4.1.172
DE   Salicyl-alcohol beta-D-glucosyltransferase.
CA   UDP-glucose + salicyl alcohol = UDP + salicin.
//
ID   2.4.1.173
DE   Sterol 3-beta-glucosyltransferase.
CA   UDP-glucose + a sterol = UDP + a sterol 3-beta-D-glucoside.
CC   -!- Not identical with EC 2.4.1.192 or EC 2.4.1.193.
DR   Q751Z4, ATG26_ASHGO;  A1CFB3, ATG26_ASPCL;  Q4WID6, ATG26_ASPFU;
DR   A2QNQ5, ATG26_ASPNC;  Q2U0C3, ATG26_ASPOR;  Q0CKU4, ATG26_ASPTN;
DR   Q5A950, ATG26_CANAL;  P0CN91, ATG26_CRYNB;  P0CN90, ATG26_CRYNJ;
DR   Q6BN88, ATG26_DEBHA;  Q5B4C9, ATG26_EMENI;  Q6CUV2, ATG26_KLULA;
DR   Q8NJS1, ATG26_LEPMC;  A1CYS1, ATG26_NEOFI;  Q7S1I0, ATG26_NEUCR;
DR   A7KAN4, ATG26_PENCW;  Q0UY53, ATG26_PHANO;  A7KAK6, ATG26_PICAN;
DR   Q9Y751, ATG26_PICPG;  A7ERM5, ATG26_SCLS1;  A7TF84, ATG26_VANPO;
DR   Q6C8M8, ATG26_YARLI;  A7A179, ATG26_YEAS7;  Q06321, ATG26_YEAST;
DR   Q54IL5, UGT52_DICDI;
//
ID   2.4.1.174
DE   Glucuronylgalactosylproteoglycan 4-beta-N-
DE   acetylgalactosaminyltransferase.
AN   Glucuronylgalactosylproteoglycan beta-1,4-N-
AN   acetylgalactosaminyltransferase.
AN   N-acetylgalactosaminyltransferase I.
AN   Uridine diphosphoacetylgalactosamine-chondroitin
AN   acetylgalactosaminyltransferase I.
CA   UDP-N-acetyl-D-galactosamine + beta-D-glucuronyl-(1->3)-D-galactosyl-
CA   proteoglycan = UDP + N-acetyl-D-galactosaminyl-(1->4)-beta-D-glucuronyl-
CA   (1->3)-beta-D-galactosylproteoglycan.
CC   -!- Involved in the biosynthesis of chondroitin sulfate.
CC   -!- Key enzyme activity for the initiation of chondroitin and dermatan
CC       sulfates, transferring GalNAc to the GlcA-Gal-Gal-Xyl-Ser core.
DR   Q8TDX6, CGAT1_HUMAN;  Q8BJQ9, CGAT1_MOUSE;  Q8N6G5, CGAT2_HUMAN;
DR   Q8C1F4, CGAT2_MOUSE;
//
ID   2.4.1.175
DE   Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-
DE   acetylgalactosaminyltransferase.
AN   Chondroitin synthase.
AN   Glucuronyl-N-acetylgalactosaminylproteoglycan beta-1,4-N-
AN   acetylgalactosaminyltransferase.
AN   N-acetylgalactosaminyltransferase II.
AN   UDP-N-acetyl-D-galactosamine:D-glucuronyl-N-acetyl-1,3-beta-D-
AN   galactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase.
AN   Uridine diphosphoacetylgalactosamine-chondroitin
AN   acetylgalactosaminyltransferase II.
CA   UDP-N-acetyl-D-galactosamine + beta-D-glucuronosyl-(1->3)-N-acetyl-beta-
CA   D-galactosaminyl-proteoglycan = UDP + N-acetyl-beta-D-galactosaminyl-
CA   (1->4)-beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-
CA   proteoglycan.
CC   -!- Involved in the biosynthesis of chondroitin sulfate.
CC   -!- The human form of this enzyme is a bifunctional glycosyltransferase,
CC       which also has the EC 2.4.1.226 activity required for the synthesis
CC       of the chondroitin sulfate disaccharide repeats.
CC   -!- Similar chondroitin synthase 'copolymerases' can be found in
CC       Pasteurella multocida and Escherichia coli.
DR   Q86X52, CHSS1_HUMAN;  Q6ZQ11, CHSS1_MOUSE;  P45895, CHSS2_CAEEL;
DR   Q8IZ52, CHSS2_HUMAN;  Q6IQX7, CHSS2_MOUSE;  Q70JA7, CHSS3_HUMAN;
DR   Q5DTK1, CHSS3_MOUSE;  Q8L0V4, CHS_ECOLX  ;  Q9CMP0, CHS_PASMU  ;
//
ID   2.4.1.176
DE   Gibberellin beta-D-glucosyltransferase.
CA   UDP-glucose + gibberellin = UDP + gibberellin 2-O-beta-D-glucoside.
CC   -!- Acts on the plant hormone gibberellin GA(3) and related compounds.
//
ID   2.4.1.177
DE   Cinnamate beta-D-glucosyltransferase.
CA   UDP-glucose + trans-cinnamate = UDP + trans-cinnamoyl beta-D-glucoside.
CC   -!- 4-coumarate, 2-coumarate, benzoate, feruloate and caffeate can also
CC       act as acceptors, more slowly.
CC   -!- Involved in the biosynthesis of chlorogenic acid in the root of the
CC       sweet potato.
DR   Q66PF4, CGT_FRAAN  ;
//
ID   2.4.1.178
DE   Hydroxymandelonitrile glucosyltransferase.
AN   Cyanohydrin glucosyltransferase.
CA   UDP-glucose + 4-hydroxymandelonitrile = UDP + taxiphyllin.
CC   -!- 3,4-dihydroxymandelonitrile can also act as acceptor.
//
ID   2.4.1.179
DE   Lactosylceramide beta-1,3-galactosyltransferase.
CA   UDP-galactose + D-galactosyl-(1->4)-beta-D-glucosyl-R = UDP +
CA   D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-R.
CC   -!- R may be an oligosaccharide or a glycolipid.
CC   -!- Lactose can also act as acceptor, more slowly.
CC   -!- Involved in the elongation of oligosaccharide chains, especially in
CC       glycolipids.
//
ID   2.4.1.180
DE   Lipopolysaccharide N-acetylmannosaminouronosyltransferase.
CA   UDP-N-acetyl-beta-D-mannosaminouronate + lipopolysaccharide = UDP +
CA   N-acetyl-beta-D-mannosaminouronosyl-(1->4)-lipopolysaccharide.
CC   -!- Involved in the biosynthesis of common antigen in Enterobacteriaceae.
//
ID   2.4.1.181
DE   Hydroxyanthraquinone glucosyltransferase.
CA   UDP-glucose + an hydroxyanthraquinone = UDP + a glucosyloxyanthraquinone.
CC   -!- A range of anthraquinones and some flavones can act as acceptors;
CC       best substrates are emodin, anthrapurpurin, quinizarin, 2,6-
CC       dihydroxyanthraquinone and 1,8-dihydroxyanthraquinone.
//
ID   2.4.1.182
DE   Lipid-A-disaccharide synthase.
CA   UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-
CA   bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-
CA   bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-
CA   bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate.
CC   -!- Involved with EC 2.3.1.129 and EC 2.7.1.130 in the biosynthesis of
CC       the phosphorylated glycolipid, lipid A, in the outer membrane of
CC       Escherichia coli.
DR   Q5X5J5, LPXB1_LEGPA;  Q5ZVR9, LPXB1_LEGPH;  Q5WWX7, LPXB1_LEGPL;
DR   Q5X0T2, LPXB2_LEGPA;  Q5ZRD7, LPXB2_LEGPH;  Q5WSK6, LPXB2_LEGPL;
DR   Q6FA07, LPXB_ACIAD ;  Q1INL4, LPXB_ACIBL ;  C1F718, LPXB_ACIC5 ;
DR   A3MY79, LPXB_ACTP2 ;  B3GZJ7, LPXB_ACTP7 ;  B0BRG6, LPXB_ACTPJ ;
DR   A0KHH6, LPXB_AERHH ;  Q0VQE4, LPXB_ALCBS ;  Q0A7J2, LPXB_ALHEH ;
DR   B6EJW7, LPXB_ALISL ;  B4RVJ5, LPXB_ALTMD ;  B8JE78, LPXB_ANAD2 ;
DR   Q2IL69, LPXB_ANADE ;  B4UHR6, LPXB_ANASK ;  O67420, LPXB_AQUAE ;
DR   Q5NZG2, LPXB_AROAE ;  A1K6Q8, LPXB_AZOSB ;  C1DST3, LPXB_AZOVD ;
DR   Q7VRD3, LPXB_BLOFL ;  Q493B9, LPXB_BLOPB ;  Q2L147, LPXB_BORA1 ;
DR   Q7WJ81, LPXB_BORBR ;  Q7WA47, LPXB_BORPA ;  A9INR9, LPXB_BORPD ;
DR   Q7VYB7, LPXB_BORPE ;  Q89KQ7, LPXB_BRAJA ;  B1YS61, LPXB_BURA4 ;
DR   Q1BHG9, LPXB_BURCA ;  B1JUD7, LPXB_BURCC ;  A0K8D0, LPXB_BURCH ;
DR   B4ECL8, LPXB_BURCJ ;  Q0BE28, LPXB_BURCM ;  A9AIM7, LPXB_BURM1 ;
DR   A3MKS9, LPXB_BURM7 ;  A2SB86, LPXB_BURM9 ;  Q62JD7, LPXB_BURMA ;
DR   A1V555, LPXB_BURMS ;  A3NWL7, LPXB_BURP0 ;  Q3JR42, LPXB_BURP1 ;
DR   A3NAT4, LPXB_BURP6 ;  B2JIB3, LPXB_BURP8 ;  B2T5I1, LPXB_BURPP ;
DR   Q63T25, LPXB_BURPS ;  Q39F56, LPXB_BURS3 ;  Q2SWY5, LPXB_BURTA ;
DR   A4JF62, LPXB_BURVG ;  Q13XC9, LPXB_BURXL ;  A8FK76, LPXB_CAMJ8 ;
DR   Q9PIK8, LPXB_CAMJE ;  Q5HWH9, LPXB_CAMJR ;  B3PBR1, LPXB_CELJU ;
DR   Q5L586, LPXB_CHLAB ;  Q821Z3, LPXB_CHLCV ;  Q255P5, LPXB_CHLFF ;
DR   Q9PJY4, LPXB_CHLMU ;  Q9Z6U3, LPXB_CHLPN ;  Q3KLU2, LPXB_CHLTA ;
DR   O84416, LPXB_CHLTR ;  Q1R020, LPXB_CHRSD ;  Q7NVY1, LPXB_CHRVO ;
DR   A8ALA6, LPXB_CITK8 ;  Q485F5, LPXB_COLP3 ;  B6J9H1, LPXB_COXB1 ;
DR   B6J161, LPXB_COXB2 ;  A9KC41, LPXB_COXBN ;  A9NCA7, LPXB_COXBR ;
DR   Q83DS5, LPXB_COXBU ;  Q470F0, LPXB_CUPPJ ;  B7KFS1, LPXB_CYAP7 ;
DR   Q47F79, LPXB_DECAR ;  Q6ALW0, LPXB_DESPS ;  A7ZHS2, LPXB_ECO24 ;
DR   B7UJ83, LPXB_ECO27 ;  B7MBG3, LPXB_ECO45 ;  B7LGP4, LPXB_ECO55 ;
DR   Q8X8X7, LPXB_ECO57 ;  B5Z0G1, LPXB_ECO5E ;  B7NIE4, LPXB_ECO7I ;
DR   B7MP42, LPXB_ECO81 ;  B7M1Y5, LPXB_ECO8A ;  C4ZRS4, LPXB_ECOBW ;
DR   B1XD51, LPXB_ECODH ;  A7ZWC8, LPXB_ECOHS ;  A1A7M6, LPXB_ECOK1 ;
DR   Q0TLF1, LPXB_ECOL5 ;  Q8FL07, LPXB_ECOL6 ;  B1IQF9, LPXB_ECOLC ;
DR   P10441, LPXB_ECOLI ;  B7N849, LPXB_ECOLU ;  B6HZF6, LPXB_ECOSE ;
DR   B1LGY4, LPXB_ECOSM ;  Q1RG07, LPXB_ECOUT ;  A4W6S7, LPXB_ENT38 ;
DR   Q6D8D0, LPXB_ERWCT ;  B2VHX9, LPXB_ERWT9 ;  B7LW61, LPXB_ESCF3 ;
DR   B0TXG8, LPXB_FRAP2 ;  Q14G55, LPXB_FRAT1 ;  A7NAP6, LPXB_FRATF ;
DR   Q2A4P3, LPXB_FRATH ;  B2SFX3, LPXB_FRATM ;  A0Q7X9, LPXB_FRATN ;
DR   Q0BN19, LPXB_FRATO ;  Q5NEQ2, LPXB_FRATT ;  A4IWJ7, LPXB_FRATW ;
DR   B3E4H8, LPXB_GEOLS ;  Q39T49, LPXB_GEOMG ;  Q74AT9, LPXB_GEOSL ;
DR   Q5FUA3, LPXB_GLUOX ;  Q0BS63, LPXB_GRABC ;  Q7VMW5, LPXB_HAEDU ;
DR   Q4QLM6, LPXB_HAEI8 ;  A5UD44, LPXB_HAEIE ;  A5UII8, LPXB_HAEIG ;
DR   P45011, LPXB_HAEIN ;  B8F5I8, LPXB_HAEPS ;  Q0I4M5, LPXB_HAES1 ;
DR   B0UW62, LPXB_HAES2 ;  Q2SBR1, LPXB_HAHCH ;  Q17WJ2, LPXB_HELAH ;
DR   B6JM91, LPXB_HELP2 ;  B5Z7M7, LPXB_HELPG ;  Q1CT05, LPXB_HELPH ;
DR   Q9ZKY2, LPXB_HELPJ ;  B2USW3, LPXB_HELPS ;  O25537, LPXB_HELPY ;
DR   Q5QYW1, LPXB_IDILO ;  B5Y1I9, LPXB_KLEP3 ;  A6T4Y4, LPXB_KLEP7 ;
DR   Q2W4D7, LPXB_MAGSA ;  A0L8R9, LPXB_MAGSM ;  Q65VI1, LPXB_MANSM ;
DR   Q1H152, LPXB_METFK ;  Q1D393, LPXB_MYXXD ;  Q5F5Y6, LPXB_NEIG1 ;
DR   Q9JX45, LPXB_NEIMA ;  Q9K1F5, LPXB_NEIMB ;  A1KRN0, LPXB_NEIMF ;
DR   Q1QMM4, LPXB_NITHX ;  Q3JAC1, LPXB_NITOC ;  Q3SRI5, LPXB_NITWN ;
DR   Q9CJK7, LPXB_PASMU ;  C6DAJ6, LPXB_PECCP ;  Q3A550, LPXB_PELCD ;
DR   C0QR27, LPXB_PERMH ;  Q7N8N4, LPXB_PHOLL ;  Q6LN37, LPXB_PHOPR ;
DR   A2C745, LPXB_PROM3 ;  P72216, LPXB_PROMI ;  Q7V5X6, LPXB_PROMM ;
DR   Q48F72, LPXB_PSE14 ;  A6V1E5, LPXB_PSEA7 ;  B7V7U5, LPXB_PSEA8 ;
DR   Q02RB5, LPXB_PSEAB ;  Q9HXY8, LPXB_PSEAE ;  Q1I639, LPXB_PSEE4 ;
DR   Q4KHG3, LPXB_PSEF5 ;  C3K6G9, LPXB_PSEFS ;  Q3IIW8, LPXB_PSEHT ;
DR   A4XWS8, LPXB_PSEMY ;  A5W837, LPXB_PSEP1 ;  Q3KH99, LPXB_PSEPF ;
DR   B0KSB2, LPXB_PSEPG ;  Q88MG7, LPXB_PSEPK ;  B1JBP7, LPXB_PSEPW ;
DR   Q886N0, LPXB_PSESM ;  Q4ZWR5, LPXB_PSEU2 ;  A1SYV0, LPXB_PSYIN ;
DR   Q1LNE5, LPXB_RALME ;  Q8XZH8, LPXB_RALSO ;  B6IST7, LPXB_RHOCS ;
DR   Q21WX7, LPXB_RHOFD ;  Q2IW93, LPXB_RHOP2 ;  Q6N5R2, LPXB_RHOPA ;
DR   Q215D6, LPXB_RHOPB ;  A8GN02, LPXB_RICAH ;  A8GU85, LPXB_RICB8 ;
DR   Q1RIC1, LPXB_RICBR ;  A8EZC6, LPXB_RICCK ;  Q92II0, LPXB_RICCN ;
DR   Q4UJN0, LPXB_RICFE ;  Q9ZDK7, LPXB_RICPR ;  Q68X51, LPXB_RICTY ;
DR   Q21HI5, LPXB_SACD2 ;  B5F8U3, LPXB_SALA4 ;  A9MPH9, LPXB_SALAR ;
DR   Q57T26, LPXB_SALCH ;  B5FJ29, LPXB_SALDC ;  B5R421, LPXB_SALEP ;
DR   B5RHG7, LPXB_SALG2 ;  B4TK57, LPXB_SALHS ;  B4SV11, LPXB_SALNS ;
DR   Q5PD72, LPXB_SALPA ;  A9N0T2, LPXB_SALPB ;  C0Q6K5, LPXB_SALPC ;
DR   B5BAN9, LPXB_SALPK ;  B4TYE2, LPXB_SALSV ;  Q8Z9A1, LPXB_SALTI ;
DR   Q8ZRN9, LPXB_SALTY ;  A8GID3, LPXB_SERP5 ;  A1S4Q3, LPXB_SHEAM ;
DR   B8E7Q3, LPXB_SHEB2 ;  Q085C9, LPXB_SHEFN ;  B0TP70, LPXB_SHEHH ;
DR   A3QG90, LPXB_SHELP ;  Q8EGG2, LPXB_SHEON ;  A8H6K3, LPXB_SHEPA ;
DR   A4Y556, LPXB_SHEPC ;  A0KZ10, LPXB_SHESA ;  A8FY29, LPXB_SHESH ;
DR   Q0HGW8, LPXB_SHESM ;  Q0HT75, LPXB_SHESR ;  A1RLL4, LPXB_SHESW ;
DR   B1KNT0, LPXB_SHEWM ;  B2U325, LPXB_SHIB3 ;  Q325V8, LPXB_SHIBS ;
DR   Q32JS7, LPXB_SHIDS ;  Q0T827, LPXB_SHIF8 ;  Q83SL3, LPXB_SHIFL ;
DR   Q3Z5H6, LPXB_SHISS ;  Q5LSU1, LPXB_SILPO ;  Q2NRM0, LPXB_SODGM ;
DR   Q02AZ6, LPXB_SOLUE ;  B2V704, LPXB_SULSY ;  Q2LVL8, LPXB_SYNAS ;
DR   Q57310, LPXB_SYNY3 ;  Q31G55, LPXB_THICR ;  Q3SKM8, LPXB_THIDA ;
DR   A1WHV5, LPXB_VEREI ;  A5F627, LPXB_VIBC3 ;  Q9KPW5, LPXB_VIBCH ;
DR   C3LQ19, LPXB_VIBCM ;  Q5E3F2, LPXB_VIBF1 ;  B5F9W3, LPXB_VIBFM ;
DR   A7MY02, LPXB_VIBHB ;  Q87MF0, LPXB_VIBPA ;  Q8DBE8, LPXB_VIBVU ;
DR   Q7MIH2, LPXB_VIBVY ;  Q8D2H4, LPXB_WIGBR ;  Q8PML8, LPXB_XANAC ;
DR   Q3BVL7, LPXB_XANC5 ;  Q4USP7, LPXB_XANC8 ;  Q8PAW6, LPXB_XANCP ;
DR   Q2P4B8, LPXB_XANOM ;  Q5H1F3, LPXB_XANOR ;  B2I7N8, LPXB_XYLF2 ;
DR   Q9PEI6, LPXB_XYLFA ;  B0U236, LPXB_XYLFM ;  Q87EI5, LPXB_XYLFT ;
DR   Q8ZH55, LPXB_YERPE ;  Q667K2, LPXB_YERPS ;
//
ID   2.4.1.183
DE   Alpha-1,3-glucan synthase.
CA   UDP-glucose + (alpha-D-glucosyl-(1->3))(n) = UDP + (alpha-D-glucosyl-
CA   (1->3))(n+1).
CC   -!- A glucan primer is needed to begin the reaction, which brings about
CC       elongation of the glucan chains.
DR   Q9USK8, AGS1_SCHPO ;  Q09854, MOK11_SCHPO;  Q9UUL4, MOK12_SCHPO;
DR   Q9Y719, MOK13_SCHPO;  Q9Y704, MOK14_SCHPO;
//
ID   2.4.1.184
DE   Galactolipid galactosyltransferase.
AN   DGDG synthase.
AN   Digalactosyldiacylglycerol synthase.
AN   Galactolipid-galactolipid galactosyltransferase.
AN   Galactolipid:galactolipid galactosyltransferase.
AN   GGGT.
AN   Interlipid galactosyltransferase.
CA   2 3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol = 3-(alpha-D-galactosyl-
CA   (1->6)-beta-D-galactosyl)-1,2-diacyl-sn-glycerol + 1,2-diacyl-
CA   sn-glycerol.
CC   -!- By further transfers of galactosyl residues to the
CC       digalactosyldiacylglycerol, trigalactosyldiacylglycerol and
CC       tetragalactosyldiacylglycerol are also formed.
CC   -!- Was originally thought to be the major enzyme involved in the
CC       production of digalactosyldiacylglycerol in plants as it masked the
CC       effect of the true enzyme (EC 2.4.1.241).
CC   -!- Its activity is localized to chloroplast envelope membranes, but it
CC       does not contribute to net galactolipid synthesis in plants.
//
ID   2.4.1.185
DE   Flavanone 7-O-beta-glucosyltransferase.
CA   UDP-glucose + a flavanone = UDP + a flavanone 7-O-beta-D-glucoside.
CC   -!- Naringenin and hesperetin can act as acceptors.
CC   -!- No action on flavones or flavonols.
//
ID   2.4.1.186
DE   Glycogenin glucosyltransferase.
AN   Glycogenin.
AN   Priming glucosyltransferase.
CA   UDP-alpha-D-glucose + glycogenin = UDP + alpha-D-glucosylglycogenin.
CF   Manganese.
CC   -!- The first reaction of this enzyme is to catalyze its own
CC       glucosylation, normally at a specific Tyr of the protein if this
CC       group is free; when the Tyr is replaced by Thr or Phe, the enzyme's
CC       self-glucosylation activity is lost but its intermolecular
CC       transglucosylation ability remains.
CC   -!- It continues to glucosylate an existing glucosyl group until a length
CC       of about 5-13 residues has been formed.
CC   -!- Further lengthening of the glycogen chain is then carried out by
CC       EC 2.4.1.11.
CC   -!- Not highly specific for the donor, using UDP-xylose in addition to
CC       UDP-glucose (although not glucosylating or xylosylating a xylosyl
CC       group so added).
CC   -!- It can also use CDP-glucose and TDP-glucose, but not ADP-glucose or
CC       GDP-glucose.
CC   -!- Similarly it is not highly specific for the acceptor, using water
CC       (i.e. hydrolyzing UDP-glucose) among others.
CC   -!- Various forms of the enzyme exist, and different forms predominate in
CC       different organs.
CC   -!- Thus primate liver contains glycogenin-2, of molecular mass 66 kDa,
CC       whereas the more widespread form is glycogenin-1, with a molecular
CC       mass of 38 kDa.
CC   -!- Formerly EC 2.4.1.112.
DR   A7A018, GLG1_YEAS7 ;  P36143, GLG1_YEAST ;  A6ZQJ2, GLG2_YEAS7 ;
DR   P47011, GLG2_YEAST ;  O15488, GLYG2_HUMAN;  P46976, GLYG_HUMAN ;
DR   Q9R062, GLYG_MOUSE ;  P13280, GLYG_RABIT ;  O08730, GLYG_RAT   ;
//
ID   2.4.1.187
DE   N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-
DE   mannosaminyltransferase.
CA   UDP-N-acetyl-D-mannosamine + N-acetyl-D-glucosaminyldiphosphoundecaprenol
CA   = UDP + N-acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-
CA   glucosaminyldiphosphoundecaprenol.
CC   -!- Involved in the biosynthesis of teichoic acid linkage units in
CC       bacterial cell walls.
DR   P27620, TAGA_BACSU ;  Q5HI32, TAGA_STAAC ;  Q99VX9, TAGA_STAAM ;
DR   Q7A714, TAGA_STAAN ;  Q6GJ34, TAGA_STAAR ;  Q6GBJ4, TAGA_STAAS ;
DR   Q9LC45, TAGA_STAAU ;  Q8NXS7, TAGA_STAAW ;  Q8RKI7, TARA_BACPZ ;
//
ID   2.4.1.188
DE   N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase.
CA   UDP-glucose + N-acetyl-D-glucosaminyldiphosphoundecaprenol = UDP + beta-
CA   D-glucosyl-(1->4)-N-acetyl-D-glucosaminyldiphosphoundecaprenol.
//
ID   2.4.1.189
DE   Luteolin 7-O-glucuronosyltransferase.
CA   UDP-glucuronate + luteolin = UDP + luteolin 7-O-beta-D-glucuronide.
//
ID   2.4.1.190
DE   Luteolin-7-O-glucuronide 2''-O-glucuronosyltransferase.
AN   LMT.
AN   Uridine diphosphoglucuronate-luteolin 7-O-glucuronide
AN   glucuronosyltransferase.
CA   UDP-glucuronate + luteolin 7-O-beta-D-glucuronide = UDP + luteolin 7-O-
CA   (beta-D-glucuronosyl-(1->2)-beta-D-glucuronide).
//
ID   2.4.1.191
DE   Luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase.
CA   UDP-glucuronate + luteolin 7-O-(beta-D-glucuronosyl-(1->2)-beta-D-
CA   glucuronide) = UDP + luteolin 7-O-(beta-D-glucuronosyl-(1->2)-beta-D-
CA   glucuronide)-4'-O-beta-D-glucuronide.
//
ID   2.4.1.192
DE   Nuatigenin 3-beta-glucosyltransferase.
CA   UDP-glucose + (20S,22S,25S)-22,25-epoxyfurost-5-ene-3-beta,26-diol =
CA   UDP + (20S,22S,25S)-22,25-epoxyfurost-5-ene-3-beta,26-diol 3-O-beta-D-
CA   glucoside.
CC   -!- Some other sapogenins can act as glucosyl acceptors.
CC   -!- Involved in the biosynthesis of plant saponins.
CC   -!- Not identical with EC 2.4.1.173 or EC 2.4.1.193.
//
ID   2.4.1.193
DE   Sarsapogenin 3-beta-glucosyltransferase.
CA   UDP-glucose + (25S)-5-beta-spirostan-3-beta-ol = UDP + (25S)-5-beta-
CA   spirostan-3-beta-ol 3-O-beta-D-glucoside.
CC   -!- Specific to 5-beta-spirostanols.
CC   -!- Involved in the biosynthesis of plant saponins.
CC   -!- Not identical with EC 2.4.1.173 or EC 2.4.1.192.
//
ID   2.4.1.194
DE   4-hydroxybenzoate 4-O-beta-D-glucosyltransferase.
CA   UDP-glucose + 4-hydroxybenzoate = UDP + 4-(beta-D-glucosyloxy)benzoate.
//
ID   2.4.1.195
DE   N-hydroxythioamide S-beta-glucosyltransferase.
AN   Desulfoglucosinolate-uridine diphosphate glucosyltransferase.
AN   Thiohydroximate beta-D-glucosyltransferase.
AN   Thiohydroximate glucosyltransferase.
AN   Thiohydroximate S-glucosyltransferase.
AN   Uridine diphosphoglucose-thiohydroximate glucosyltransferase.
CA   UDP-glucose + N-hydroxy-2-phenylethanethioamide = UDP +
CA   desulfoglucotropeolin.
CC   -!- Involved with EC 2.8.2.24 in the biosynthesis of thioglucosides in
CC       cruciferous plants.
PR   PROSITE; PDOC00359;
DR   O48676, U74B1_ARATH;
//
ID   2.4.1.196
DE   Nicotinate glucosyltransferase.
CA   UDP-glucose + nicotinate = UDP + N-glucosylnicotinate.
//
ID   2.4.1.197
DE   High-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase.
CA   Transfers an N-acetyl-D-glucosamine residue from UDP-N-acetyl-D-
CA   glucosamine to the 4-position of a mannose linked alpha-(1->6) to the
CA   core mannose of high-mannose oligosaccharides produced by Dictyostelium
CA   discoideum.
CC   -!- The activity of the intersecting mannose residue as acceptor is
CC       dependent on two other mannose residues attached by alpha-1,3 and
CC       alpha-1,6 links.
//
ID   2.4.1.198
DE   Phosphatidylinositol N-acetylglucosaminyltransferase.
AN   UDP-N-acetyl-D-glucosamine:phosphatidylinositol N-acetyl-D-
AN   glucosaminyltransferase.
AN   Uridine diphosphoacetylglucosamine alpha-1,6-acetyl-D-
AN   glucosaminyltransferase.
CA   UDP-N-acetyl-D-glucosamine + 1-phosphatidyl-1D-myo-inositol = UDP +
CA   6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol.
CC   -!- Involved in the first step of glycosylphosphatidylinositol (GPI)
CC       anchor formation in all eukaryotes.
CC   -!- In mammalian cells, the enzyme is composed of at least five subunits
CC       (PIG-A, PIG-H, PIG-C, GPI1 and PIG-P).
CC   -!- PIG-A subunit is the catalytic subunit.
CC   -!- In some species, the long-chain acyl groups of the phosphatidyl group
CC       are partly replaced by long-chain alkyl or alk-1-enyl groups.
DR   Q9Y7L7, GPI15_SCHPO;  P53961, GPI15_YEAST;  Q756D4, GPI19_ASHGO;
DR   Q04082, GPI19_YEAST;  P53306, GPI1_YEAST ;  O59802, GPI2_SCHPO ;
DR   P46961, GPI2_YEAST ;  P87172, GPI3_SCHPO ;  B3LKQ3, GPI3_YEAS1 ;
DR   B5VSZ6, GPI3_YEAS6 ;  A6ZW78, GPI3_YEAS7 ;  P32363, GPI3_YEAST ;
DR   P37287, PIGA_HUMAN ;  Q3ZBX1, PIGC_BOVIN ;  Q54M40, PIGC_DICDI ;
DR   Q92535, PIGC_HUMAN ;  Q9CXR4, PIGC_MOUSE ;  Q5PQQ4, PIGC_RAT   ;
DR   Q32L89, PIGH_BOVIN ;  Q14442, PIGH_HUMAN ;  Q5M9N4, PIGH_MOUSE ;
DR   O64792, PIGP_ARATH ;  P57054, PIGP_HUMAN ;  Q9JHG1, PIGP_MOUSE ;
DR   Q5R946, PIGP_PONAB ;  Q9BRB3, PIGQ_HUMAN ;  Q9QYT7, PIGQ_MOUSE ;
//
ID   2.4.1.199
DE   Beta-mannosylphosphodecaprenol--mannooligosaccharide
DE   6-mannosyltransferase.
CA   Beta-D-mannosylphosphodecaprenol + (1->6)-alpha-D-mannosyloligosaccharide
CA   = decaprenol phosphate + (1->6)-alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-
CA   oligosaccharide.
CC   -!- Involved in the formation of mannooligosaccharides in the membrane of
CC       Mycobacterium smegmatis.
//
ID   2.4.1.200
DE   Transferred entry: 4.2.2.17.
//
ID   2.4.1.201
DE   Alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase.
AN   GnTVI.
AN   Mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase.
AN   N-acetylglucosaminyltransferase VI.
AN   N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase
AN   VI.
AN   Uridine diphosphoacetylglucosamine-glycopeptide beta-
AN   1->4-acetylglucosaminyltransferase VI.
CA   UDP-N-acetyl-D-glucosamine + 2,6-bis(N-acetyl-beta-D-glucosaminyl)-alpha-
CA   D-mannosyl-R = UDP + 2,4,6-tris(N-acetyl-beta-D-glucosaminyl)-alpha-D-
CA   mannosyl-R.
CC   -!- R represents the remainder of the N-linked oligosaccharide in the
CC       glycoprotein acceptor.
//
ID   2.4.1.202
DE   2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-
DE   glucosyltransferase.
CA   UDP-glucose + 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one = UDP +
CA   2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucoside.
//
ID   2.4.1.203
DE   Trans-zeatin O-beta-D-glucosyltransferase.
AN   Uridine diphosphoglucose-zeatin O-glucosyltransferase.
AN   Zeatin O-beta-D-glucosyltransferase.
AN   Zeatin O-glucosyltransferase.
CA   UDP-glucose + trans-zeatin = UDP + O-beta-D-glucosyl-trans-zeatin.
CC   -!- Unlike EC 2.4.1.215, UDP-xylose can also act as donor (cf.
CC       EC 2.4.2.40).
DR   Q9ZSK5, ZOG_PHALU  ;
//
ID   2.4.1.204
DE   Transferred entry: 2.4.2.40.
//
ID   2.4.1.205
DE   Galactogen 6-beta-galactosyltransferase.
AN   1,6-D-galactosyltransferase.
CA   UDP-galactose + galactogen = UDP + (1->6)-beta-D-galactosylgalactogen.
CC   -!- Galactogen from Helix pomatia is the most effective acceptor.
//
ID   2.4.1.206
DE   Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase.
CA   UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->4)-beta-D-glucosyl-
CA   (1<->1)-ceramide = UDP + N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-
CA   galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide.
//
ID   2.4.1.207
DE   Xyloglucan:xyloglucosyl transferase.
AN   Endo-xyloglucan transferase.
AN   Xyloglucan endotransglycosylase.
CA   Breaks a beta-(1->4) bond in the backbone of a xyloglucan and transfers
CA   the xyloglucanyl segment on to O-4 of the non-reducing terminal glucose
CA   residue of an acceptor, which can be a xyloglucan or an oligosaccharide
CA   of xyloglucan.
CC   -!- Does not use cello-oligosaccharides as either donor or acceptor.
DR   Q9ZVK1, XTH10_ARATH;  Q9SMP1, XTH11_ARATH;  Q9FKL9, XTH12_ARATH;
DR   Q9FKL8, XTH13_ARATH;  Q9ZSU4, XTH14_ARATH;  Q38911, XTH15_ARATH;
DR   Q8LG58, XTH16_ARATH;  O80803, XTH17_ARATH;  Q9M0D2, XTH18_ARATH;
DR   Q9M0D1, XTH19_ARATH;  Q9SV61, XTH1_ARATH ;  Q40144, XTH1_SOLLC ;
DR   Q9FI31, XTH20_ARATH;  Q9ZV40, XTH21_ARATH;  Q38857, XTH22_ARATH;
DR   Q38910, XTH23_ARATH;  P24806, XTH24_ARATH;  Q38907, XTH25_ARATH;
DR   Q9SVV2, XTH26_ARATH;  Q8LDS2, XTH27_ARATH;  Q38909, XTH28_ARATH;
DR   Q8L7H3, XTH29_ARATH;  Q9SV60, XTH2_ARATH ;  Q38908, XTH30_ARATH;
DR   P93046, XTH31_ARATH;  Q9SJL9, XTH32_ARATH;  Q8LC45, XTH33_ARATH;
DR   Q9LJR7, XTH3_ARATH ;  Q39099, XTH4_ARATH ;  Q9XIW1, XTH5_ARATH ;
DR   Q8LF99, XTH6_ARATH ;  Q8LER3, XTH7_ARATH ;  Q8L9A9, XTH8_ARATH ;
DR   Q76BW5, XTH8_ORYSJ ;  Q8LDW9, XTH9_ARATH ;  Q41638, XTHA_PHAAN ;
DR   Q8LNZ5, XTHB_PHAAN ;  Q6YDN9, XTH_BRAOB  ;  Q39857, XTH_SOYBN  ;
DR   P93349, XTH_TOBAC  ;  Q41542, XTH_WHEAT  ;
//
ID   2.4.1.208
DE   Diglucosyl diacylglycerol synthase.
AN   DGlcDAG synthase.
AN   MGlcDAG (1->2) glucosyltransferase.
AN   Monoglucosyl diacylglycerol (1->2) glucosyltransferase.
CA   UDP-glucose + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol = 1,2-
CA   diacyl-3-O-(alpha-D-glucopyranosyl-(1->2)-O-alpha-D-glucopyranosyl)-
CA   sn-glycerol + UDP.
CF   Magnesium.
//
ID   2.4.1.209
DE   Cis-p-coumarate glucosyltransferase.
CA   UDP-glucose + cis-p-coumarate = 4'-O-beta-D-glucosyl-cis-p-coumarate +
CA   UDP.
CC   -!- Cis-caffeic acid also serves as a glucosyl acceptor with the enzyme
CC       from Sphagnum fallax kinggr.
CC   -!- The corresponding trans-isomers are not substrates.
//
ID   2.4.1.210
DE   Limonoid glucosyltransferase.
AN   LGTase.
AN   Limonoid UDP-glucosyltransferase.
CA   UDP-glucose + limonin = glucosyl-limonin + UDP.
CC   -!- The enzyme purified from navel orange albedo tissue also acts on the
CC       related tetranortriterpenoid nomilin.
PR   PROSITE; PDOC00359;
DR   Q9MB73, LGT_CITUN  ;
//
ID   2.4.1.211
DE   1,3-beta-galactosyl-N-acetylhexosamine phosphorylase.
AN   Galacto-N-biose phosphorylase.
AN   Lacto-N-biose phosphorylase.
AN   LNBP.
CA   Beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine + phosphate =
CA   alpha-D-galactopyranose 1-phosphate + N-acetyl-D-glucosamine.
CC   -!- Reaction also occurs with beta-D-galactopyranosyl-(1->3)-N-acetyl-D-
CC       galactosamine as the substrate, giving N-acetyl-D-galactosamine as
CC       the product.
DR   A9KQ75, GAHP1_CLOPH;  A9KIW5, GAHP2_CLOPH;
//
ID   2.4.1.212
DE   Hyaluronan synthase.
AN   HAS.
CA   (1) UDP-alpha-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-N-
CA   acetyl-beta-D-glucosaminyl-(1->4)-(nascent hyaluronan) = UDP + N-acetyl-
CA   beta-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-
CA   glucosaminyl-(1->4)-(nascent hyaluronan).
CA   (2) UDP-alpha-D-glucuronate + N-acetyl-beta-D-glucosaminyl-(1->4)-beta-D-
CA   glucuronosyl-(1->3)-(nascent hyaluronan) = UDP + beta-D-glucuronosyl-
CA   (1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-
CA   (nascent hyaluronan).
CF   Magnesium.
CC   -!- Adds GlcNAc to nascent hyaluronan when the non-reducing end is GlcA,
CC       but it adds GlcA when the non-reducing end is GlcNAc.
CC   -!- Highly specific for UDP-GlcNAc and UDP-GlcA; no copolymerization is
CC       observed if either is replaced by UDP-Glc, UDP-Gal, UDP-GalNAc or
CC       UDP-GalA.
DR   Q92839, HAS1_HUMAN ;  Q61647, HAS1_MOUSE ;  P13563, HAS1_XENLA ;
DR   B1WB39, HAS1_XENTR ;  O97711, HAS2_BOVIN ;  O57424, HAS2_CHICK ;
DR   Q92819, HAS2_HUMAN ;  P70312, HAS2_MOUSE ;  O35776, HAS2_RAT   ;
DR   O57427, HAS2_XENLA ;  O57425, HAS3_CHICK ;  O00219, HAS3_HUMAN ;
DR   O08650, HAS3_MOUSE ;  O57426, HAS3_XENLA ;  P0C0H1, HASA_STRP1 ;
DR   P0DB60, HASA_STRP3 ;  Q5X9A9, HASA_STRP6 ;  Q8NKX1, HASA_STRP8 ;
DR   P0DB61, HASA_STRPQ ;  P0C0H0, HASA_STRPY ;  Q7BLV3, HAS_PASMD  ;
//
ID   2.4.1.213
DE   Glucosylglycerol-phosphate synthase.
AN   GG-phosphate synthase.
AN   GGPS.
AN   Glucosyl-glycerol-phosphate synthase.
CA   ADP-glucose + sn-glycerol 3-phosphate = 2-(beta-D-glucosyl)-sn-glycerol
CA   3-phosphate + ADP.
CC   -!- Acts with EC 3.1.3.69 to form glucosylglycerol, an osmolyte that
CC       endows cyanobacteria with resistance to salt.
DR   Q93JY3, GGPS_PSEAG ;  O65979, GGPS_SYNP2 ;  P74258, GGPS_SYNY3 ;
//
ID   2.4.1.214
DE   Glycoprotein 3-alpha-L-fucosyltransferase.
AN   GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fuc-alpha-1->6-GlcNAc)-Asn-
AN   peptide) alpha-1->3-fucosyltransferase.
AN   GDP-L-Fuc:Asn-linked GlcNAc alpha-1,3-fucosyltransferase.
AN   GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-1,3-fucosyltransferase.
CA   GDP-L-fucose + N(4)-(N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-
CA   mannosyl-(1->3)-(N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-
CA   (1->6))-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-
CA   acetyl-beta-D-glucosaminyl)asparagine = GDP + N(4)-(N-acetyl-beta-D-
CA   glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-(N-acetyl-beta-D-
CA   glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6))-beta-D-mannosyl-(1->4)-N-
CA   acetyl-beta-D-glucosaminyl-(1->4)-(alpha-L-fucosyl-(1->3))-N-acetyl-beta-
CA   D-glucosaminyl)asparagine.
CF   Manganese.
CC   -!- The enzyme transfers to N-linked oligosaccharide structures
CC       (N-glycans), generally with a specificity for N-glycans with one
CC       unsubstituted non-reducing terminal GlcNAc residue.
CC   -!- This enzyme catalyzes a reaction similar to that of EC 2.4.1.68,
CC       but transferring the L-fucosyl group from GDP-beta-L-fucose to form
CC       an alpha-1,3-linkage rather than an alpha-1,6-linkage.
CC   -!- The N-glycan products of this enzyme are present in plants, insects
CC       and some other invertebrates (e.g., Schistosoma, Haemonchus,
CC       Lymnaea).
DR   Q9VUL9, FUCTA_DROME;  Q9LJK1, FUT11_ARATH;
//
ID   2.4.1.215
DE   Cis-zeatin O-beta-D-glucosyltransferase.
CA   UDP-glucose + cis-zeatin = UDP + O-beta-D-glucosyl-cis-zeatin.
CC   -!- The enzyme from maize can use cis-zeatin and UDPglucose as
CC       substrates, but not cis-ribosylzeatin, trans-zeatin or trans-
CC       ribosylzeatin.
CC   -!- Unlike EC 2.4.1.203 UDP-xylose cannot act as a donor.
PR   PROSITE; PDOC00359;
DR   Q93XP7, CZOG1_MAIZE;  Q8RXA5, CZOG2_MAIZE;  Q6JAH0, CZOG_SORBI ;
//
ID   2.4.1.216
DE   Trehalose 6-phosphate phosphorylase.
AN   Trehalose 6-phosphate:phosphate beta-D-glucosyltransferase.
CA   Alpha,alpha-trehalose 6-phosphate + phosphate = glucose 6-phosphate +
CA   beta-D-glucose 1-phosphate.
CC   -!- The enzyme from Lactococcus lactis is specific for trehalose
CC       6-phosphate.
CC   -!- Differs from EC 2.4.1.64 in that trehalose is not a substrate.
DR   Q9CID5, TREPP_LACLA;
//
ID   2.4.1.217
DE   Mannosyl-3-phosphoglycerate synthase.
AN   MPG synthase.
CA   GDP-mannose + 3-phospho-D-glycerate = GDP + 2-(alpha-D-mannosyl)-3-
CA   phosphoglycerate.
CF   Magnesium.
CC   -!- The enzyme is absolutely specific for GDP-mannose and
CC       3-phosphoglycerate, and transfers the mannosyl group with retention
CC       of configuration.
CC   -!- In the hyperthermophilic archaeon Pyrococcus horikoshii,
CC       the mannosyl-3-phosphoglycerate formed is subsequently
CC       dephosphorylated by a specific phosphatase, EC 3.1.3.70, producing
CC       mannosylglycerate.
DR   Q9YDM5, MPGS_AERPE ;  Q9UZC1, MPGS_PYRAB ;  Q8U380, MPGS_PYRFU ;
DR   O58689, MPGS_PYRHO ;
//
ID   2.4.1.218
DE   Hydroquinone glucosyltransferase.
AN   Arbutin synthase.
AN   Hydroquinone:O-glucosyltransferase.
CA   UDP-glucose + hydroquinone = UDP + hydroquinone-O-beta-D-glucopyranoside.
CC   -!- Hydroquinone is the most effective acceptor, but over 40 phenolic
CC       compounds are also glucosylated, but at lower rates.
DR   Q9AR73, HQGT_RAUSE ;  Q9M156, U72B1_ARATH;
//
ID   2.4.1.219
DE   Vomilenine glucosyltransferase.
AN   UDPG:vomilenine 21-beta-D-glucosyltransferase.
CA   UDP-glucose + vomilenine = UDP + raucaffricine.
CC   -!- The indole alkaloid raucaffricine accumulates during the culture of
CC       Rauvolfia cell suspensions.
//
ID   2.4.1.220
DE   Indoxyl-UDPG glucosyltransferase.
AN   Indoxyl-UDPG-glucosyltransferase.
CA   UDP-glucose + indoxyl = UDP + indican.
CC   -!- Also acts to a limited extent on 4-, 5-, 6- and 7-hydroxyindole.
CC   -!- After enzymic or chemical hydrolysis, indican forms indoxyl, which,
CC       in turn, is converted in the presence of oxygen to the dye indigo.
//
ID   2.4.1.221
DE   Peptide-O-fucosyltransferase.
AN   GDP-fucose protein O-fucosyltransferase.
AN   GDP-fucose:polypeptide fucosyltransferase.
AN   GDP-L-fucose:polypeptide fucosyltransferase.
CA   Transfers an alpha-L-fucosyl residue from GDP-beta-L-fucose to the serine
CA   hydroxy group of a protein acceptor.
CC   -!- Involved in the biosynthesis of O-fucosylated epidermal growth factor
CC       (EGF) and thrombospondin type 1 repeats.
CC   -!- The attachment of O-linked fucose to serine or threonine occurs on
CC       EGF domains within the sequence Cys-Xaa-Xaa-Gly-Gly-Ser/Thr-Cys.
DR   Q18014, OFUT1_CAEEL;  P83337, OFUT1_CRIGR;  Q9V6X7, OFUT1_DROME;
DR   Q9H488, OFUT1_HUMAN;  Q91ZW2, OFUT1_MOUSE;  Q6EV69, OFUT1_PANTR;
DR   Q6EV70, OFUT1_RAT  ;  Q8WR51, OFUT2_CAEEL;  Q9W589, OFUT2_DROME;
DR   Q9Y2G5, OFUT2_HUMAN;  Q8VHI3, OFUT2_MOUSE;  Q6EV56, OFUT2_PANTR;
//
ID   2.4.1.222
DE   O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase.
AN   O-fucosylpeptide beta-1,3-N-acetylglucosaminyltransferase.
CA   Transfers a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue
CA   of a fucosylated protein acceptor.
CC   -!- O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferases are the
CC       products of fringe genes.
CC   -!- O-linked fucose is an unusual form of glycosylation where the fucose
CC       is attached directly to proteins through the hydroxy groups of Ser or
CC       Thr residues.
DR   Q24342, FNG_DROME  ;  Q2KJ92, LFNG_BOVIN ;  O12971, LFNG_CHICK ;
DR   Q8JHF2, LFNG_DANRE ;  Q8NES3, LFNG_HUMAN ;  O09010, LFNG_MOUSE ;
DR   Q924T4, LFNG_RAT   ;  P79948, LFNG_XENLA ;  Q5YB40, MFNG_DANRE ;
DR   O00587, MFNG_HUMAN ;  O09008, MFNG_MOUSE ;  Q5IS64, MFNG_PANTR ;
DR   O12972, RFNG_CHICK ;  Q6KFX9, RFNG_DANRE ;  Q9Y644, RFNG_HUMAN ;
DR   O09009, RFNG_MOUSE ;  Q9YHB3, RFNG_NOTVI ;  Q9R1U9, RFNG_RAT   ;
DR   P79949, RFNG_XENLA ;
//
ID   2.4.1.223
DE   Glucuronyl-galactosyl-proteoglycan 4-alpha-N-
DE   acetylglucosaminyltransferase.
AN   Alpha-1,4-N-acetylglucosaminyltransferase.
AN   Alpha-N-acetylglucosaminyltransferase I.
AN   Glucuronosylgalactosyl-proteoglycan 4-alpha-N-
AN   acetylglucosaminyltransferase.
CA   UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-beta-D-
CA   galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan =
CA   UDP + alpha-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-
CA   beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-
CA   proteoglycan.
CC   -!- Enzyme involved in the initiation of heparin and heparan sulfate
CC       synthesis, transferring GlcNAc to the (GlcA-Gal-Gal-Xyl-)Ser core.
CC   -!- Apparently products of both the human EXTL2 and EXTL3 genes can
CC       catalyze this reaction.
CC   -!- In Caenorhabditis elegans, the product of the rib-2 gene displays
CC       this activity as well as that of EC 2.4.1.224.
DR   O01705, EXT2_CAEEL ;  Q9XZ08, EXT3_DROME ;  Q9UBQ6, EXTL2_HUMAN;
DR   Q9ES89, EXTL2_MOUSE;  O43909, EXTL3_HUMAN;  Q9WVL6, EXTL3_MOUSE;
//
ID   2.4.1.224
DE   Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-
DE   acetylglucosaminyltransferase.
AN   Alpha-N-acetylglucosaminyltransferase II.
AN   Glucuronyl-N-acetylglucosaminylproteoglycan alpha-1,4-N-
AN   acetylglucosaminyltransferase.
CA   UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-
CA   glucosaminyl-proteoglycan = UDP + N-acetyl-alpha-D-glucosaminyl-(1->4)-
CA   beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan.
CC   -!- Involved in the biosynthesis of heparin and heparan sulfate.
CC   -!- Some forms of the enzyme from human (particularly the enzyme complex
CC       encoded by the EXT1 and EXT2 genes) act as bifunctional
CC       glycosyltransferases, which also have the EC 2.4.1.225 activity
CC       required for the synthesis of the heparan sulfate disaccharide
CC       repeats.
CC   -!- Other human forms of this enzyme (e.g. the product of the EXTL1 gene)
CC       have only the 4-alpha-N-acetylglucosaminyltransferase activity.
CC   -!- In Caenorhabditis elegans, the product of the rib-2 gene displays the
CC       activities of this enzyme as well as EC 2.4.1.223.
DR   Q5IGR8, EXT1A_DANRE;  Q5IGR7, EXT1B_DANRE;  Q5IGR6, EXT1C_DANRE;
DR   A5D7I4, EXT1_BOVIN ;  Q9JK82, EXT1_CRIGR ;  Q9V730, EXT1_DROME ;
DR   Q16394, EXT1_HUMAN ;  P97464, EXT1_MOUSE ;  A9X1C8, EXT1_PAPAN ;
DR   Q5RBC3, EXT1_PONAB ;  O77783, EXT2_BOVIN ;  O01705, EXT2_CAEEL ;
DR   Q9Y169, EXT2_DROME ;  Q93063, EXT2_HUMAN ;  P70428, EXT2_MOUSE ;
DR   Q92935, EXTL1_HUMAN;  Q9JKV7, EXTL1_MOUSE;
//
ID   2.4.1.225
DE   N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase.
AN   Heparan glucuronyltransferase II.
AN   N-acetylglucosaminylproteoglycan beta-1,4-glucuronyltransferase.
CA   UDP-alpha-D-glucuronate + N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-
CA   glucuronosyl-proteoglycan = UDP + beta-D-glucuronosyl-(1->4)-N-acetyl-
CA   alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan.
CC   -!- Involved in the biosynthesis of heparin and heparan sulfate.
CC   -!- Some forms of the human enzyme (particularly the enzyme complex
CC       encoded by the EXT1 and EXT2 genes) act as bifunctional
CC       glycosyltransferases, which also have the EC 2.4.1.244 activity
CC       required for the synthesis of the heparan sulfate disaccharide
CC       repeats.
DR   Q5IGR8, EXT1A_DANRE;  Q5IGR7, EXT1B_DANRE;  Q5IGR6, EXT1C_DANRE;
DR   A5D7I4, EXT1_BOVIN ;  Q9JK82, EXT1_CRIGR ;  Q9V730, EXT1_DROME ;
DR   Q16394, EXT1_HUMAN ;  P97464, EXT1_MOUSE ;  A9X1C8, EXT1_PAPAN ;
DR   Q5RBC3, EXT1_PONAB ;  O77783, EXT2_BOVIN ;  Q9Y169, EXT2_DROME ;
DR   Q93063, EXT2_HUMAN ;  P70428, EXT2_MOUSE ;
//
ID   2.4.1.226
DE   N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase.
AN   Chondroitin glucuronyltransferase II.
CA   UDP-alpha-D-glucuronate + N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-
CA   glucuronosyl-proteoglycan = UDP + beta-D-glucuronosyl-(1->3)-N-acetyl-
CA   beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan.
CC   -!- Involved in the biosynthesis of chondroitin and dermatan sulfate.
CC   -!- The human chondroitin synthetase is a bifunctional
CC       glycosyltransferase, which also has the EC 2.4.1.175 activity
CC       required for the synthesis of the chondroitin sulfate disaccharide
CC       repeats.
CC   -!- Similar chondroitin synthase 'copolymerases' can be found in
CC       Pasteurella multocida and Escherichia coli.
CC   -!- There is also another human protein with apparently only the 3-beta-
CC       glucuronosyltransferase activity.
DR   Q9P2E5, CHPF2_HUMAN;  Q86X52, CHSS1_HUMAN;  Q6ZQ11, CHSS1_MOUSE;
DR   P45895, CHSS2_CAEEL;  Q8IZ52, CHSS2_HUMAN;  Q6IQX7, CHSS2_MOUSE;
DR   Q70JA7, CHSS3_HUMAN;  Q5DTK1, CHSS3_MOUSE;  Q8L0V4, CHS_ECOLX  ;
DR   Q9CMP0, CHS_PASMU  ;  Q7BLV3, HAS_PASMD  ;
//
ID   2.4.1.227
DE   Undecaprenyldiphospho-muramoylpentapeptide beta-N-
DE   acetylglucosaminyltransferase.
AN   MurG transferase.
AN   UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-
AN   undecaprenol N-acetylglucosamine transferase.
AN   Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
CA   UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-
CA   Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-
CA   D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.
CC   -!- The enzyme also works when the lysine residue is replaced by meso-
CC       2,6-diaminoheptanedioate (meso-2,6-diaminopimelate, A2pm) combined
CC       with adjacent residues through its L-center, as it is in Gram-
CC       negative and some Gram-positive organisms.
CC   -!- The undecaprenol involved is ditrans,octacis-undecaprenol.
DR   A0RHC3, MURG1_BACAH;  Q81JG5, MURG1_BACAN;  Q732F8, MURG1_BACC1;
DR   Q812W5, MURG1_BACCR;  Q636B6, MURG1_BACCZ;  Q6HEQ4, MURG1_BACHK;
DR   A0RHT1, MURG2_BACAH;  Q81JE6, MURG2_BACAN;  Q730T5, MURG2_BACC1;
DR   Q812T8, MURG2_BACCR;  Q634T3, MURG2_BACCZ;  Q6HDR3, MURG2_BACHK;
DR   A0RIN0, MURG3_BACAH;  Q812Y1, MURG3_BACCR;  A1TKD1, MURG_ACIAC ;
DR   Q6F703, MURG_ACIAD ;  B7GV73, MURG_ACIB3 ;  B7ICE5, MURG_ACIB5 ;
DR   B2I1J5, MURG_ACIBC ;  Q1IKH0, MURG_ACIBL ;  B0VNZ9, MURG_ACIBS ;
DR   A3M9Y1, MURG_ACIBT ;  B0V9F5, MURG_ACIBY ;  A0LTM3, MURG_ACIC1 ;
DR   A5FUL0, MURG_ACICJ ;  B9MFR2, MURG_ACIET ;  B7J3V2, MURG_ACIF2 ;
DR   B5ELC3, MURG_ACIF5 ;  A1WC06, MURG_ACISJ ;  A3MY90, MURG_ACTP2 ;
DR   B3GZK8, MURG_ACTP7 ;  B0BRH7, MURG_ACTPJ ;  A0KPX2, MURG_AERHH ;
DR   A4SI56, MURG_AERS4 ;  B9JH51, MURG_AGRRK ;  Q8UDM8, MURG_AGRT5 ;
DR   B9JY54, MURG_AGRVS ;  Q0VS02, MURG_ALCBS ;  Q0A6K2, MURG_ALHEH ;
DR   B6ELH5, MURG_ALISL ;  A6TS61, MURG_ALKMQ ;  A8MH36, MURG_ALKOO ;
DR   B4RWX9, MURG_ALTMD ;  B3ET95, MURG_AMOA5 ;  B8J8E8, MURG_ANAD2 ;
DR   Q2IG27, MURG_ANADE ;  A7HH67, MURG_ANADF ;  Q5PB22, MURG_ANAMM ;
DR   B4UES1, MURG_ANASK ;  Q3M935, MURG_ANAVT ;  B7GGI2, MURG_ANOFW ;
DR   O67238, MURG_AQUAE ;  Q5P6Z6, MURG_AROAE ;  A1R5F8, MURG_ARTAT ;
DR   A0JV94, MURG_ARTS2 ;  A1K3U6, MURG_AZOSB ;  C1DQ99, MURG_AZOVD ;
DR   A7Z4E5, MURG_BACA2 ;  A7GRN6, MURG_BACCN ;  Q5LIJ7, MURG_BACFN ;
DR   Q64ZM1, MURG_BACFR ;  Q9K9T0, MURG_BACHD ;  Q65JY0, MURG_BACLD ;
DR   A8FCY1, MURG_BACP2 ;  Q5WAE4, MURG_BACSK ;  P37585, MURG_BACSU ;
DR   Q8A258, MURG_BACTN ;  A6L071, MURG_BACV8 ;  A1UTC5, MURG_BARBK ;
DR   Q6G2Q5, MURG_BARHE ;  Q6G124, MURG_BARQU ;  A9IWA5, MURG_BART1 ;
DR   Q1LSW5, MURG_BAUCH ;  Q6MIG1, MURG_BDEBA ;  A1A2E9, MURG_BIFAA ;
DR   B3DQN1, MURG_BIFLD ;  Q8CY50, MURG_BIFLO ;  B7GQ78, MURG_BIFLS ;
DR   Q7U346, MURG_BLOFL ;  Q493Q1, MURG_BLOPB ;  Q2KVG0, MURG_BORA1 ;
DR   Q0SM88, MURG_BORAP ;  Q7WFS2, MURG_BORBR ;  O51708, MURG_BORBU ;
DR   B7J0L2, MURG_BORBZ ;  Q660A8, MURG_BORGA ;  B2S1A8, MURG_BORHD ;
DR   Q7W4B4, MURG_BORPA ;  A9I4V2, MURG_BORPD ;  Q7VUQ3, MURG_BORPE ;
DR   A1R0I9, MURG_BORT9 ;  Q89FU7, MURG_BRAJA ;  A5EPK4, MURG_BRASB ;
DR   A4YZK3, MURG_BRASO ;  B2S6Q4, MURG_BRUA1 ;  Q2YLY5, MURG_BRUA2 ;
DR   Q57C78, MURG_BRUAB ;  A9M690, MURG_BRUC2 ;  C0RE70, MURG_BRUMB ;
DR   Q8YI66, MURG_BRUME ;  A5VRH7, MURG_BRUO2 ;  B0CHM0, MURG_BRUSI ;
DR   Q8CY39, MURG_BRUSU ;  B8D914, MURG_BUCA5 ;  P57311, MURG_BUCAI ;
DR   Q8K9T4, MURG_BUCAP ;  B8D7B9, MURG_BUCAT ;  P59424, MURG_BUCBP ;
DR   B1YSS4, MURG_BURA4 ;  Q1BZG3, MURG_BURCA ;  B1JV78, MURG_BURCC ;
DR   A0K486, MURG_BURCH ;  B4E6J2, MURG_BURCJ ;  Q0BIK1, MURG_BURCM ;
DR   A9AI96, MURG_BURM1 ;  A3MR63, MURG_BURM7 ;  A2S5U5, MURG_BURM9 ;
DR   Q62GS7, MURG_BURMA ;  A1V0R8, MURG_BURMS ;  A3NZL5, MURG_BURP0 ;
DR   Q3JND8, MURG_BURP1 ;  A3NDW4, MURG_BURP6 ;  B2JHG0, MURG_BURP8 ;
DR   B2SYX6, MURG_BURPP ;  Q63QJ7, MURG_BURPS ;  Q39JX0, MURG_BURS3 ;
DR   Q2SZI3, MURG_BURTA ;  A4JB94, MURG_BURVG ;  Q13TZ2, MURG_BURXL ;
DR   A4XI04, MURG_CALS8 ;  A0RP87, MURG_CAMFF ;  A7I265, MURG_CAMHC ;
DR   A8FM88, MURG_CAMJ8 ;  A7H2Z9, MURG_CAMJD ;  Q9PNQ2, MURG_CAMJE ;
DR   A1W027, MURG_CAMJJ ;  Q5HU62, MURG_CAMJR ;  Q3AAE6, MURG_CARHZ ;
DR   B8H091, MURG_CAUCN ;  Q9A5A1, MURG_CAUCR ;  B3PCM0, MURG_CELJU ;
DR   Q5L524, MURG_CHLAB ;  Q3ANV3, MURG_CHLCH ;  Q820E0, MURG_CHLCV ;
DR   Q255W4, MURG_CHLFF ;  B3EIK8, MURG_CHLL2 ;  Q9PLG2, MURG_CHLMU ;
DR   B3QLW4, MURG_CHLP8 ;  A1BJX8, MURG_CHLPD ;  Q9Z702, MURG_CHLPN ;
DR   B0B8Y7, MURG_CHLT2 ;  B3QWT7, MURG_CHLT3 ;  Q3KKT1, MURG_CHLTA ;
DR   B0BAL6, MURG_CHLTB ;  Q8KGD4, MURG_CHLTE ;  O84766, MURG_CHLTR ;
DR   Q1QVG7, MURG_CHRSD ;  Q7NPZ9, MURG_CHRVO ;  A8ALK6, MURG_CITK8 ;
DR   A5CS51, MURG_CLAM3 ;  B0RIJ3, MURG_CLAMS ;  Q97GY4, MURG_CLOAB ;
DR   A7FX11, MURG_CLOB1 ;  C3L230, MURG_CLOB6 ;  A6M1F0, MURG_CLOB8 ;
DR   B2V1X5, MURG_CLOBA ;  B2TLE0, MURG_CLOBB ;  A5I5J5, MURG_CLOBH ;
DR   C1FUF9, MURG_CLOBJ ;  B1IKH3, MURG_CLOBK ;  A7GGX9, MURG_CLOBL ;
DR   B1KYH7, MURG_CLOBM ;  B8I6H3, MURG_CLOCE ;  Q182Y6, MURG_CLOD6 ;
DR   A5MZ55, MURG_CLOK5 ;  A0Q182, MURG_CLONN ;  Q0TNP7, MURG_CLOP1 ;
DR   Q8XIQ1, MURG_CLOPE ;  A9KK83, MURG_CLOPH ;  Q0SRB4, MURG_CLOPS ;
DR   Q893R7, MURG_CLOTE ;  A3DE27, MURG_CLOTH ;  Q47VQ9, MURG_COLP3 ;
DR   Q6NGC8, MURG_CORDI ;  Q8FNU0, MURG_COREF ;  A4QFM3, MURG_CORGB ;
DR   Q8NNN5, MURG_CORGL ;  Q4JW95, MURG_CORJK ;  B6J5K3, MURG_COXB1 ;
DR   B6J2Q3, MURG_COXB2 ;  A9KER3, MURG_COXBN ;  A9NA44, MURG_COXBR ;
DR   Q820X3, MURG_COXBU ;  Q0K6M4, MURG_CUPNH ;  Q46WZ4, MURG_CUPPJ ;
DR   B1WVP7, MURG_CYAA5 ;  B7KGH1, MURG_CYAP7 ;  B7K5Z6, MURG_CYAP8 ;
DR   Q11RH5, MURG_CYTH3 ;  Q47AA4, MURG_DECAR ;  C1CW40, MURG_DEIDV ;
DR   Q1IXV9, MURG_DEIGD ;  Q9RWP0, MURG_DEIRA ;  C6BYG6, MURG_DESAD ;
DR   B1I4C4, MURG_DESAP ;  Q313Q3, MURG_DESDG ;  B8FT56, MURG_DESHD ;
DR   Q24TE6, MURG_DESHY ;  C4XK69, MURG_DESMR ;  Q6AJ53, MURG_DESPS ;
DR   A4J2B1, MURG_DESRM ;  Q728U8, MURG_DESVH ;  B8DP79, MURG_DESVM ;
DR   A1VBE8, MURG_DESVV ;  A5EY03, MURG_DICNV ;  B5YEL3, MURG_DICT6 ;
DR   B8E325, MURG_DICTD ;  A7ZHI1, MURG_ECO24 ;  B7UIE0, MURG_ECO27 ;
DR   B7MAL3, MURG_ECO45 ;  B7LFW0, MURG_ECO55 ;  Q8X9Y8, MURG_ECO57 ;
DR   B5YZC6, MURG_ECO5E ;  B7NHJ6, MURG_ECO7I ;  B7MNU9, MURG_ECO81 ;
DR   B7M133, MURG_ECO8A ;  C4ZRI5, MURG_ECOBW ;  B1XC67, MURG_ECODH ;
DR   A7ZW42, MURG_ECOHS ;  A1A7D5, MURG_ECOK1 ;  Q0TLP9, MURG_ECOL5 ;
DR   Q8FL64, MURG_ECOL6 ;  B1IR88, MURG_ECOLC ;  P17443, MURG_ECOLI ;
DR   B7N7W3, MURG_ECOLU ;  B6HZ67, MURG_ECOSE ;  B1LG27, MURG_ECOSM ;
DR   Q1RGA5, MURG_ECOUT ;  B2KE54, MURG_ELUMP ;  O07109, MURG_ENTFA ;
DR   O07670, MURG_ENTHR ;  A7MIE5, MURG_ENTS8 ;  Q6D0I3, MURG_ERWCT ;
DR   B2VD91, MURG_ERWT9 ;  Q2NCZ0, MURG_ERYLH ;  B7LWF6, MURG_ESCF3 ;
DR   C4Z1B5, MURG_EUBE2 ;  B1YIT7, MURG_EXIS2 ;  C4L5U5, MURG_EXISA ;
DR   B0S0Z5, MURG_FINM2 ;  A5FIY3, MURG_FLAJ1 ;  A6H195, MURG_FLAPJ ;
DR   Q0RNP1, MURG_FRAAA ;  B0TY93, MURG_FRAP2 ;  Q2JD50, MURG_FRASC ;
DR   Q14I26, MURG_FRAT1 ;  A7NDC0, MURG_FRATF ;  Q2A2I7, MURG_FRATH ;
DR   B2SGS8, MURG_FRATM ;  A0Q766, MURG_FRATN ;  Q0BL37, MURG_FRATO ;
DR   Q5NGM4, MURG_FRATT ;  A4IX64, MURG_FRATW ;  Q8R5N5, MURG_FUSNN ;
DR   B5EBQ1, MURG_GEOBB ;  Q5L3H6, MURG_GEOKA ;  B3E3Y2, MURG_GEOLS ;
DR   Q39YL9, MURG_GEOMG ;  B9M172, MURG_GEOSF ;  Q748D6, MURG_GEOSL ;
DR   C6DZK6, MURG_GEOSM ;  C5D4C2, MURG_GEOSW ;  A4IJS4, MURG_GEOTN ;
DR   A5G8K0, MURG_GEOUR ;  Q7MBC4, MURG_GLOVI ;  Q5FUJ5, MURG_GLUOX ;
DR   Q0BV25, MURG_GRABC ;  A0M527, MURG_GRAFK ;  Q7U336, MURG_HAEDU ;
DR   Q4QLF8, MURG_HAEI8 ;  A5UCW8, MURG_HAEIE ;  A5UIR2, MURG_HAEIG ;
DR   P45065, MURG_HAEIN ;  B8F3B6, MURG_HAEPS ;  Q0I1D3, MURG_HAES1 ;
DR   Q2S9Z2, MURG_HAHCH ;  A1WYU3, MURG_HALHL ;  B8CWJ6, MURG_HALOH ;
DR   Q17WB5, MURG_HELAH ;  Q7U322, MURG_HELHP ;  B6JMZ5, MURG_HELP2 ;
DR   B5Z8F1, MURG_HELPG ;  Q1CSB1, MURG_HELPH ;  Q9ZK59, MURG_HELPJ ;
DR   B2UUR4, MURG_HELPS ;  O25770, MURG_HELPY ;  A4G8T8, MURG_HERAR ;
DR   Q0BXU2, MURG_HYPNA ;  Q5R0M1, MURG_IDILO ;  A6T2F8, MURG_JANMA ;
DR   Q28NN5, MURG_JANSC ;  B5Y1U7, MURG_KLEP3 ;  A6T4N3, MURG_KLEP7 ;
DR   Q5FKV2, MURG_LACAC ;  Q03QH5, MURG_LACBA ;  Q039R7, MURG_LACC3 ;
DR   B3WDY2, MURG_LACCB ;  Q1GAT5, MURG_LACDA ;  Q04B72, MURG_LACDB ;
DR   B2GB78, MURG_LACF3 ;  Q042P9, MURG_LACGA ;  A8YUN9, MURG_LACH4 ;
DR   Q74JY4, MURG_LACJO ;  Q9CF92, MURG_LACLA ;  A2RJQ4, MURG_LACLM ;
DR   Q02XY0, MURG_LACLS ;  Q88V81, MURG_LACPL ;  A5VJ33, MURG_LACRD ;
DR   B2G6K5, MURG_LACRJ ;  Q1WTA0, MURG_LACS1 ;  Q38XM8, MURG_LACSS ;
DR   Q1MPB9, MURG_LAWIP ;  Q5X6U5, MURG_LEGPA ;  A5IGA6, MURG_LEGPC ;
DR   Q5ZXC4, MURG_LEGPH ;  Q5WY98, MURG_LEGPL ;  Q6AE64, MURG_LEIXX ;
DR   Q04V94, MURG_LEPBJ ;  Q04Y82, MURG_LEPBL ;  Q72R84, MURG_LEPIC ;
DR   Q8F4J1, MURG_LEPIN ;  B1MXW0, MURG_LEUCK ;  Q03W35, MURG_LEUMM ;
DR   Q929Y2, MURG_LISIN ;  C1KWY8, MURG_LISMC ;  Q71XX8, MURG_LISMF ;
DR   B8DBP8, MURG_LISMH ;  Q8Y5M2, MURG_LISMO ;  A0AKD5, MURG_LISW6 ;
DR   Q2W0H3, MURG_MAGSA ;  A0L5N1, MURG_MAGSM ;  Q65RY6, MURG_MANSM ;
DR   A1U3F8, MURG_MARAV ;  Q0AMW7, MURG_MARMM ;  Q11GS5, MURG_MESSB ;
DR   B7KSC1, MURG_METC4 ;  Q604V7, MURG_METCA ;  A9VWV3, MURG_METEP ;
DR   Q1GZ01, MURG_METFK ;  B8IN64, MURG_METNO ;  B1ZGP4, MURG_METPB ;
DR   A2SCY5, MURG_METPP ;  B1LXZ4, MURG_METRJ ;  B0UFC7, MURG_METS4 ;
DR   B0JFZ1, MURG_MICAN ;  Q2RK79, MURG_MOOTA ;  A0QF52, MURG_MYCA1 ;
DR   Q7VEP8, MURG_MYCBO ;  A1KKJ6, MURG_MYCBP ;  C1AQ69, MURG_MYCBT ;
DR   B8ZQQ0, MURG_MYCLB ;  O69552, MURG_MYCLE ;  B2HGR6, MURG_MYCMM ;
DR   Q73YQ8, MURG_MYCPA ;  A0R016, MURG_MYCS2 ;  A3Q1L8, MURG_MYCSJ ;
DR   A1UI54, MURG_MYCSK ;  Q1B6X1, MURG_MYCSS ;  A5U4I0, MURG_MYCTA ;
DR   O06224, MURG_MYCTU ;  A0PTI7, MURG_MYCUA ;  A1TAW8, MURG_MYCVP ;
DR   Q1D0T0, MURG_MYXXD ;  B2A2H2, MURG_NATTJ ;  Q5F6L8, MURG_NEIG1 ;
DR   B4RQC5, MURG_NEIG2 ;  A9M2H3, MURG_NEIM0 ;  Q9JSZ7, MURG_NEIMA ;
DR   Q9K0Y2, MURG_NEIMB ;  A1KVL3, MURG_NEIMF ;  Q0AJE1, MURG_NITEC ;
DR   Q82VS3, MURG_NITEU ;  Q1QNU3, MURG_NITHX ;  Q2Y638, MURG_NITMU ;
DR   Q3J789, MURG_NITOC ;  A6Q579, MURG_NITSB ;  Q3STS8, MURG_NITWN ;
DR   Q5YYX9, MURG_NOCFA ;  A1SL80, MURG_NOCSJ ;  B2J8J9, MURG_NOSP7 ;
DR   Q8YZI3, MURG_NOSS1 ;  Q2G995, MURG_NOVAD ;  Q8CUL4, MURG_OCEIH ;
DR   A6WZQ6, MURG_OCHA4 ;  Q04ET0, MURG_OENOB ;  B1ZU31, MURG_OPITP ;
DR   A5CEL6, MURG_ORITB ;  B3CRE9, MURG_ORITI ;  A6LEU3, MURG_PARD8 ;
DR   A1BAL5, MURG_PARDP ;  Q6MBS7, MURG_PARUW ;  P57817, MURG_PASMU ;
DR   C6DEU3, MURG_PECCP ;  Q03EY2, MURG_PEDPA ;  Q3A2G6, MURG_PELCD ;
DR   Q3B129, MURG_PELLD ;  B4SH49, MURG_PELPB ;  A1AU61, MURG_PELPD ;
DR   A5D145, MURG_PELTS ;  Q4FPK5, MURG_PELUB ;  B4RFS0, MURG_PHEZH ;
DR   Q7N147, MURG_PHOLL ;  Q6LMF6, MURG_PHOPR ;  A1VST6, MURG_POLNA ;
DR   Q12EL5, MURG_POLSJ ;  A4SV74, MURG_POLSQ ;  B2RIF1, MURG_PORG3 ;
DR   Q7MAW5, MURG_PORGI ;  B4S6Q9, MURG_PROA2 ;  Q6A9Q2, MURG_PROAC ;
DR   A3PAR5, MURG_PROM0 ;  A2C027, MURG_PROM1 ;  A8G2K3, MURG_PROM2 ;
DR   A2CDG1, MURG_PROM3 ;  A9BDG0, MURG_PROM4 ;  A2BUH4, MURG_PROM5 ;
DR   Q31CY4, MURG_PROM9 ;  Q7VDZ2, MURG_PROMA ;  B4F111, MURG_PROMH ;
DR   Q7V466, MURG_PROMM ;  Q7V388, MURG_PROMP ;  A2BNZ2, MURG_PROMS ;
DR   Q46HH6, MURG_PROMT ;  A4SH02, MURG_PROVI ;  Q48EF8, MURG_PSE14 ;
DR   Q15Q17, MURG_PSEA6 ;  A6VB85, MURG_PSEA7 ;  B7UZJ0, MURG_PSEA8 ;
DR   Q02H28, MURG_PSEAB ;  Q9HW01, MURG_PSEAE ;  Q1I5B8, MURG_PSEE4 ;
DR   Q4K6J3, MURG_PSEF5 ;  C3KCT0, MURG_PSEFS ;  Q3IFY0, MURG_PSEHT ;
DR   A4XQS4, MURG_PSEMY ;  A5W8Q0, MURG_PSEP1 ;  Q3K744, MURG_PSEPF ;
DR   B0KFS6, MURG_PSEPG ;  Q88N76, MURG_PSEPK ;  B1J3L2, MURG_PSEPW ;
DR   Q87WY5, MURG_PSESM ;  Q4ZNZ0, MURG_PSEU2 ;  A4VIH8, MURG_PSEU5 ;
DR   Q4FQV9, MURG_PSYA2 ;  Q1Q944, MURG_PSYCK ;  A1SU19, MURG_PSYIN ;
DR   Q1LIM6, MURG_RALME ;  Q8XVI7, MURG_RALSO ;  B3PTW0, MURG_RHIE6 ;
DR   Q2K6C1, MURG_RHIEC ;  Q1ME33, MURG_RHIL3 ;  Q98KB3, MURG_RHILO ;
DR   B5ZWJ4, MURG_RHILW ;  Q92NL9, MURG_RHIME ;  C3MEM9, MURG_RHISN ;
DR   B6IRG2, MURG_RHOCS ;  C1A0X5, MURG_RHOE4 ;  Q21SW9, MURG_RHOFD ;
DR   C1AU55, MURG_RHOOB ;  Q2IYK8, MURG_RHOP2 ;  Q07PT3, MURG_RHOP5 ;
DR   Q6N411, MURG_RHOPA ;  Q211T8, MURG_RHOPB ;  Q133X1, MURG_RHOPS ;
DR   Q2RVU4, MURG_RHORT ;  A3PHS8, MURG_RHOS1 ;  Q3J4M2, MURG_RHOS4 ;
DR   A4WQD5, MURG_RHOS5 ;  Q0SHS1, MURG_RHOSR ;  C3PND5, MURG_RICAE ;
DR   A8GNC7, MURG_RICAH ;  A8GVJ7, MURG_RICB8 ;  Q1RI55, MURG_RICBR ;
DR   A8EZ14, MURG_RICCK ;  Q92I58, MURG_RICCN ;  Q4ULT6, MURG_RICFE ;
DR   A8F1I4, MURG_RICM5 ;  Q9ZDC0, MURG_RICPR ;  C4K2A6, MURG_RICPU ;
DR   B0BXF6, MURG_RICRO ;  A8GRZ6, MURG_RICRS ;  Q68WW7, MURG_RICTY ;
DR   Q163J0, MURG_ROSDO ;  A5UZT7, MURG_ROSS1 ;  Q1AVX3, MURG_RUBXD ;
DR   A1AWE8, MURG_RUTMC ;  Q21MG9, MURG_SACD2 ;  A4FLW0, MURG_SACEN ;
DR   B5F7W4, MURG_SALA4 ;  A9MQC2, MURG_SALAR ;  Q57TD0, MURG_SALCH ;
DR   B5FI72, MURG_SALDC ;  B5R2M4, MURG_SALEP ;  B5RH64, MURG_SALG2 ;
DR   B4TJ87, MURG_SALHS ;  B4SU50, MURG_SALNS ;  Q5PDC8, MURG_SALPA ;
DR   A9MZL9, MURG_SALPB ;  B5BLC2, MURG_SALPK ;  Q2S528, MURG_SALRD ;
DR   B4TXH8, MURG_SALSV ;  Q8Z9G9, MURG_SALTI ;  Q8ZRU3, MURG_SALTY ;
DR   A8G9S7, MURG_SERP5 ;  A1S2F9, MURG_SHEAM ;  B8E698, MURG_SHEB2 ;
DR   A3CZM1, MURG_SHEB5 ;  A6WID1, MURG_SHEB8 ;  A9KY29, MURG_SHEB9 ;
DR   Q12SC6, MURG_SHEDO ;  Q07WI5, MURG_SHEFN ;  B0TQN7, MURG_SHEHH ;
DR   A3QIM1, MURG_SHELP ;  Q8CX35, MURG_SHEON ;  A8H984, MURG_SHEPA ;
DR   A4Y2N6, MURG_SHEPC ;  B8CNL1, MURG_SHEPW ;  A0L1P2, MURG_SHESA ;
DR   A8FQA0, MURG_SHESH ;  Q0HE83, MURG_SHESM ;  Q0HZR6, MURG_SHESR ;
DR   A1REZ6, MURG_SHESW ;  Q9F1N0, MURG_SHEVD ;  B1KKX7, MURG_SHEWM ;
DR   B2U295, MURG_SHIB3 ;  Q326E5, MURG_SHIBS ;  Q32K02, MURG_SHIDS ;
DR   Q0T8A7, MURG_SHIF8 ;  Q83MN4, MURG_SHIFL ;  Q3Z5R9, MURG_SHISS ;
DR   Q5LU63, MURG_SILPO ;  Q1GIV1, MURG_SILST ;  A6UB85, MURG_SINMW ;
DR   Q2NVV1, MURG_SODGM ;  Q01Q48, MURG_SOLUE ;  A9FI55, MURG_SORC5 ;
DR   Q1GRX9, MURG_SPHAL ;  A7X2A2, MURG_STAA1 ;  A6U1N8, MURG_STAA2 ;
DR   Q2FH20, MURG_STAA3 ;  Q2FYL5, MURG_STAA8 ;  A5ISU9, MURG_STAA9 ;
DR   Q2YY01, MURG_STAAB ;  Q5HG02, MURG_STAAC ;  A6QGX0, MURG_STAAE ;
DR   P65481, MURG_STAAM ;  P65482, MURG_STAAN ;  Q6GGZ0, MURG_STAAR ;
DR   Q6G9E3, MURG_STAAS ;  A8Z3Z7, MURG_STAAT ;  Q8NWR4, MURG_STAAW ;
DR   B9DNZ7, MURG_STACT ;  Q5HPC0, MURG_STAEQ ;  Q8CMM3, MURG_STAES ;
DR   Q4L6C8, MURG_STAHJ ;  Q49XM9, MURG_STAS1 ;  Q3K2P3, MURG_STRA1 ;
DR   Q8E6P0, MURG_STRA3 ;  Q8CX15, MURG_STRA5 ;  Q820F6, MURG_STRAW ;
DR   Q9ZBA5, MURG_STRCO ;  Q9X4H4, MURG_STRCU ;  C0M6J2, MURG_STRE4 ;
DR   B4U1U4, MURG_STREM ;  A8AW15, MURG_STRGC ;  Q8DVE2, MURG_STRMU ;
DR   P65483, MURG_STRP1 ;  Q04LK0, MURG_STRP2 ;  P0DC56, MURG_STRP3 ;
DR   B5E2Z9, MURG_STRP4 ;  Q5XB05, MURG_STRP6 ;  C1C649, MURG_STRP7 ;
DR   P65484, MURG_STRP8 ;  Q1JAT5, MURG_STRPB ;  Q1JKY5, MURG_STRPC ;
DR   Q1JG11, MURG_STRPD ;  Q1J5S6, MURG_STRPF ;  A2RDL0, MURG_STRPG ;
DR   B1IAM4, MURG_STRPI ;  B8ZMZ7, MURG_STRPJ ;  Q48SK9, MURG_STRPM ;
DR   P0CB60, MURG_STRPN ;  P0DC57, MURG_STRPQ ;  B2IN77, MURG_STRPS ;
DR   B5XMA2, MURG_STRPZ ;  Q8DQM1, MURG_STRR6 ;  A4VZT9, MURG_STRS2 ;
DR   C0MD54, MURG_STRS7 ;  A3CLN6, MURG_STRSV ;  A4VTK4, MURG_STRSY ;
DR   Q5M0D4, MURG_STRT1 ;  Q5M4Y1, MURG_STRT2 ;  Q03L97, MURG_STRTD ;
DR   B9DUV6, MURG_STRU0 ;  C1CD52, MURG_STRZJ ;  C1CJF3, MURG_STRZP ;
DR   C1CQG5, MURG_STRZT ;  Q30PK0, MURG_SULDN ;  A6Q722, MURG_SULNB ;
DR   B2V7Y8, MURG_SULSY ;  Q67Q48, MURG_SYMTH ;  Q2LR48, MURG_SYNAS ;
DR   Q31KS7, MURG_SYNE7 ;  Q2JW21, MURG_SYNJA ;  Q2JJR4, MURG_SYNJB ;
DR   Q5N140, MURG_SYNP6 ;  A5GPC2, MURG_SYNPW ;  Q7U3U6, MURG_SYNPX ;
DR   A5GW69, MURG_SYNR3 ;  Q0I6M0, MURG_SYNS3 ;  Q3AVX2, MURG_SYNS9 ;
DR   Q3AGT7, MURG_SYNSC ;  Q0AYQ8, MURG_SYNWW ;  P74657, MURG_SYNY3 ;
DR   B7IHN7, MURG_THEAB ;  Q8DHY4, MURG_THEEB ;  Q47QW9, MURG_THEFY ;
DR   A8F4X1, MURG_THELT ;  A6LLF1, MURG_THEM4 ;  Q9WY74, MURG_THEMA ;
DR   B9K6P7, MURG_THENN ;  A5IKI9, MURG_THEP1 ;  B0K8K7, MURG_THEP3 ;
DR   B0K3H0, MURG_THEPX ;  B1L9S1, MURG_THESQ ;  Q72JP9, MURG_THET2 ;
DR   Q8R9G6, MURG_THETN ;  B5YFT4, MURG_THEYD ;  Q31I59, MURG_THICR ;
DR   Q3SMH3, MURG_THIDA ;  C4LA25, MURG_TOLAT ;  Q73L91, MURG_TREDE ;
DR   O83535, MURG_TREPA ;  B2S3B6, MURG_TREPS ;  Q119X8, MURG_TRIEI ;
DR   Q83HK1, MURG_TROW8 ;  Q820Y4, MURG_TROWT ;  A1WRL1, MURG_VEREI ;
DR   A5CWW1, MURG_VESOH ;  A5F5M9, MURG_VIBC3 ;  Q9KPG7, MURG_VIBCH ;
DR   C3LQU6, MURG_VIBCM ;  Q5E2Q0, MURG_VIBF1 ;  B5FB35, MURG_VIBFM ;
DR   A7MXR6, MURG_VIBHB ;  Q87SG4, MURG_VIBPA ;  B7VJ03, MURG_VIBSL ;
DR   Q8DEL0, MURG_VIBVU ;  Q7MNV1, MURG_VIBVY ;  Q8D2Z6, MURG_WIGBR ;
DR   Q73I55, MURG_WOLPM ;  B3CM87, MURG_WOLPP ;  Q7MAD4, MURG_WOLSU ;
DR   Q5GS79, MURG_WOLTR ;  C0R2W7, MURG_WOLWR ;  Q8PPA8, MURG_XANAC ;
DR   Q3BXF2, MURG_XANC5 ;  Q4UQX0, MURG_XANC8 ;  B0RVA5, MURG_XANCB ;
DR   Q8PCK0, MURG_XANCP ;  Q2NZB8, MURG_XANOM ;  Q5GW41, MURG_XANOR ;
DR   B2I9B3, MURG_XYLF2 ;  Q9PF81, MURG_XYLFA ;  B0U4Z7, MURG_XYLFM ;
DR   Q87AF9, MURG_XYLFT ;  A1JJJ3, MURG_YERE8 ;  A7FM66, MURG_YERP3 ;
DR   Q1C214, MURG_YERPA ;  B2K4E6, MURG_YERPB ;  Q8ZIE9, MURG_YERPE ;
DR   A9R124, MURG_YERPG ;  Q1CMM7, MURG_YERPN ;  A4TQ83, MURG_YERPP ;
DR   Q66EK5, MURG_YERPS ;  B1JK81, MURG_YERPY ;  Q9RNM6, MURG_ZYMMO ;
//
ID   2.4.1.228
DE   Lactosylceramide 4-alpha-galactosyltransferase.
AN   Gal-beta-1-4Glc-beta-1-Cer alpha-1,4-galactosyltransferase.
AN   Globotriaosylceramide/CD77 synthase.
AN   Histo-blood group P(k) UDP-galactose.
CA   UDP-galactose + beta-D-galactosyl-(1->4)-D-glucosyl-(1<->1)-ceramide =
CA   UDP + alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-D-glucosyl-
CA   (1<->1)-ceramide.
DR   Q9N290, A4GAT_GORGO;  Q9NPC4, A4GAT_HUMAN;  Q67BJ4, A4GAT_MOUSE;
DR   Q9N291, A4GAT_PANTR;  Q9N289, A4GAT_PONPY;  Q9JI93, A4GAT_RAT  ;
//
ID   2.4.1.229
DE   [Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase.
AN   Skp1-HyPro GlcNAc-transferase.
AN   UDP-GlcNAc:hydroxyproline polypeptide GlcNAc-transferase.
AN   UDP-GlcNAc:Skp1-hydroxyproline GlcNAc-transferase.
AN   UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc-
AN   transferase.
CA   UDP-N-acetylglucosamine + [Skp1-protein]-hydroxyproline = UDP + [Skp1-
CA   protein]-O-(N-acetyl-D-glucosaminyl)hydroxyproline.
CC   -!- Requires dithiothreitol and a divalent cation for activity.
CC   -!- This enzyme commences the building up of a pentasaccharide (Gal-
CC       alpha-1-6Gal-alpha-1-L-Fuc-alpha-1-2Gal-beta-1-3GlcNAc) on Hyp-143 of
CC       the Dictyostelium protein Skp1, which is required for the
CC       ubiquitination of cell-cycle regulatory proteins and transcription
CC       factors.
CC   -!- The fucose residue is probably in the alpha configuration.
CC   -!- The specificity of the enzyme for Skp1-Hyp-143 and its high affinity
CC       for this substrate suggests that it is the GlcNAc-transferase that
CC       modifies Skp1 in vivo.
DR   Q8T1C6, GNT1_DICDI ;
//
ID   2.4.1.230
DE   Kojibiose phosphorylase.
CA   2-alpha-D-glucosyl-D-glucose + phosphate = D-glucose + beta-D-glucose
CA   1-phosphate.
CC   -!- The enzyme from Thermoanaerobacter brockii can act with alpha-1,2-
CC       oligoglucans, such as selaginose, as substrate, but more slowly.
CC   -!- The enzyme is inactive when dissaccharides with linkages other than
CC       alpha-1,2 linkages, such as sophorose, trehalose, neotrehalose,
CC       nigerose, laminaribiose, maltose, cellobiose, isomaltose,
CC       gentiobiose, sucrose and lactose, are used as substrates.
DR   Q8L163, KOJP_THEBR ;  Q8RBL8, KOJP_THETN ;
//
ID   2.4.1.231
DE   Alpha,alpha-trehalose phosphorylase (configuration-retaining).
AN   Trehalose phosphorylase.
CA   Alpha,alpha-trehalose + phosphate = alpha-D-glucose + alpha-D-glucose
CA   1-phosphate.
CC   -!- Unlike EC 2.4.1.64, this enzyme retains its anomeric configuration.
CC   -!- Vanadate is a strong competitive inhibitor of this reversible
CC       reaction.
DR   O75003, TREPH_GRIFR;  A6YRN9, TREPH_PLEPU;  Q9UV63, TREPH_PLESA;
//
ID   2.4.1.232
DE   Initiation-specific alpha-1,6-mannosyltransferase.
AN   Alpha-1,6-mannosyltransferase.
AN   Glycolipid 6-alpha-mannosyltransferase.
CA   Transfers an alpha-D-mannosyl residue from GDP-mannose into lipid-linked
CA   oligosaccharide, forming an alpha-(1->6)-D-mannosyl-D-mannose linkage.
CF   Manganese.
CC   -!- In Saccharomyces cerevisiae, this enzyme catalyzes an essential step
CC       in the outer chain elongation of N-linked oligosaccharides.
CC   -!- Man(8)GlcNAc and Man(9)GlcNAc are equally good substrates.
DR   Q9UTR6, OCH1_SCHPO ;  P31755, OCH1_YEAST ;
//
ID   2.4.1.233
DE   Transferred entry: 2.4.1.115.
//
ID   2.4.1.234
DE   Kaempferol 3-O-galactosyltransferase.
AN   F3GalTase.
CA   UDP-galactose + kaempferol = UDP + kaempferol 3-O-beta-D-galactoside.
CC   -!- Acts on the endogenous flavonols kaempferol and quercetin, to a
CC       lesser extent on myricetin and fisetin, and weakly on galangin and
CC       isorhamnetin.
CC   -!- The reaction can occur equally well in both directions.
DR   Q9SBQ8, KGLT_PETHY ;
//
ID   2.4.1.235
DE   Deleted entry.
//
ID   2.4.1.236
DE   Flavanone 7-O-glucoside 2''-O-beta-L-rhamnosyltransferase.
AN   1->2 UDP-rhamnosyltransferase.
AN   UDP-rhamnose:flavanone-7-O-glucoside-2''-O-rhamnosyltransferase.
CA   UDP-L-rhamnose + a flavanone 7-O-glucoside = UDP + a flavanone 7-O-(beta-
CA   L-rhamnosyl-(1->2)-beta-D-glucoside).
CC   -!- Acts on the 7-O-glucoside of naringenin and hesperetin, also the
CC       flavone 7-O-glucosides of luteolin and apigenin.
DR   Q8GVE3, FLRT_CITMA ;
//
ID   2.4.1.237
DE   Flavonol 7-O-beta-glucosyltransferase.
AN   UDP-glucose:flavonol 7-O-glucosyltransferase.
CA   UDP-glucose + a flavonol = UDP + a flavonol 7-O-beta-D-glucoside.
CC   -!- Acts on the flavonols gossypetin (8-hydroxyquercetin) and to a lesser
CC       extent on quercetin, kaempferol and myricetin.
//
ID   2.4.1.238
DE   Anthocyanin 3'-O-beta-glucosyltransferase.
AN   3'GT.
AN   UDP-glucose:anthocyanin 3'-O-glucosyltransferase.
CA   UDP-glucose + an anthocyanin = UDP + an anthocyanin 3'-O-beta-D-
CA   glucoside.
CC   -!- This enzyme specifically glucosylates the 3'-hydroxy group of
CC       delphinidin-3-O-glucosyl-5-O-(6-O-caffeoylglucosyl)-3'-O-(6-O-
CC       caffeoylglucoside)-type anthocyanins containing glucose groups at the
CC       3 and 5 positions.
CC   -!- Acts on delphinidin 3,5-di-O-glucoside in gentian (Gentiana
CC       triflora).
DR   Q8H0F2, ANGT_GENTR ;
//
ID   2.4.1.239
DE   Flavonol-3-O-glucoside glucosyltransferase.
CA   UDP-glucose + a flavonol 3-O-beta-D-glucoside = UDP + a flavonol 3-O-
CA   beta-D-glucosyl-(1->2)-beta-D-glucoside.
CC   -!- One of three specific glucosyltransferases in pea (Pisum sativum)
CC       that successively add a beta-D-glucosyl group first to O-3 of
CC       kaempferol, and then to O-2 of the previously added glucosyl group
CC       giving the 3-O-sophoroside and then the 3-O-sophorotrioside (see also
CC       EC 2.4.1.91 and EC 2.4.1.240).
CC   -!- TDP-glucose can replace UDP-glucose as the glucose donor but the
CC       reaction proceeds more slowly.
//
ID   2.4.1.240
DE   Flavonol-3-O-glycoside glucosyltransferase.
CA   UDP-glucose + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside =
CA   UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-
CA   D-glucoside.
CC   -!- One of three specific glucosyltransferases in pea (Pisum sativum)
CC       that successively add a beta-D-glucosyl group first to O-3 of
CC       kaempferol, and then to O-2 of the previously added glucosyl group
CC       giving the 3-O-sophoroside and then the 3-O-sophorotrioside (see also
CC       EC 2.4.1.91 and EC 2.4.1.239).
//
ID   2.4.1.241
DE   Digalactosyldiacylglycerol synthase.
AN   DGDG synthase.
AN   UDP-galactose-dependent DGDG synthase.
AN   UDP-galactose-dependent digalactosyldiacylglycerol synthase.
AN   UDP-galactose:MGDG galactosyltransferase.
CA   UDP-galactose + 3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol = UDP +
CA   3-(alpha-D-galactosyl-(1->6)-beta-D-galactosyl)-1,2-diacyl-sn-glycerol.
CF   Magnesium.
CC   -!- Diacylglycerol cannot serve as an acceptor molecule for
CC       galactosylation as in the reaction catalyzed by EC 2.4.1.46.
CC   -!- When phosphate is limiting, phospholipids in plant membranes are
CC       reduced but these are replaced, at least in part, by the glycolipids
CC       digalactosyldiacylglycerol (DGDG) and sulfoquinovosyldiacylglycerol.
CC   -!- While both DGD1 and DGD2 are increased under phosphate-limiting
CC       conditions, DGD2 does not contribute significantly under optimal
CC       growth conditions.
CC   -!- DGD2 is responsible for the synthesis of DGDG molecular species that
CC       are rich in C16 fatty acids at sn-1 of diacylglycerol whereas DGD1
CC       leads to molecular species rich in C18 fatty acids.
CC   -!- The enzyme has been localized to the outer side of chloroplast
CC       envelope membranes.
DR   Q9S7D1, DGDG1_ARATH;  Q6DW74, DGDG1_LOTJA;  Q6DW76, DGDG1_SOYBN;
DR   Q8W1S1, DGDG2_ARATH;  Q6DW73, DGDG2_LOTJA;  Q6DW75, DGDG2_SOYBN;
//
ID   2.4.1.242
DE   NDP-glucose--starch glucosyltransferase.
AN   GBSS.
AN   GBSSI.
AN   GBSSII.
AN   Granule-bound starch synthase.
AN   Granule-bound starch synthase I.
AN   Granule-bound starch synthase II.
AN   NDPglucose-starch glucosyltransferase.
AN   Starch granule-bound nucleoside diphosphate glucose-starch
AN   glucosyltransferase.
AN   Starch synthase II.
AN   Waxy protein.
CA   NDP-glucose + (1,4-alpha-D-glucosyl)(n) = NDP + (1,4-alpha-D-
CA   glucosyl)(n+1).
CC   -!- Unlike EC 2.4.1.11 and EC 2.4.1.21 which use UDP-glucose and ADP-
CC       glucose, respectively, this enzyme can use either UDP- or ADP-
CC       glucose.
CC   -!- Mutants that lack the Wx (waxy) allele cannot produce this enzyme,
CC       which plays an important role in the normal synthesis of amylose.
CC   -!- In such mutants, only amylopectin is produced in the endosperm or
CC       pollen.
DR   Q8LL05, SSG1B_HORVU;  P84766, SSG1_AEGTS ;  Q9MAQ0, SSG1_ARATH ;
DR   P84633, SSG1_FAGES ;  P09842, SSG1_HORVU ;  Q42857, SSG1_IPOBA ;
DR   P04713, SSG1_MAIZE ;  Q43784, SSG1_MANES ;  Q42968, SSG1_ORYGL ;
DR   P0C585, SSG1_ORYSA ;  A2Y8X2, SSG1_ORYSI ;  Q0DEV5, SSG1_ORYSJ ;
DR   Q43092, SSG1_PEA   ;  P84765, SSG1_SECCE ;  Q00775, SSG1_SOLTU ;
DR   Q43134, SSG1_SORBI ;  P27736, SSG1_WHEAT ;
//
ID   2.4.1.243
DE   6(G)-fructosyltransferase.
AN   6(G)-FFT.
AN   6(G)-fructotransferase.
AN   6(G)-FT.
AN   Fructan:fructan 6(G)-fructosyltransferase.
CA   (1-beta-D-fructofuranosyl-(2->1)-)(m+1) alpha-D-glucopyranoside +
CA   (1-beta-D-fructofuranosyl-(2->1)-)(n+1) alpha-D-glucopyranoside =
CA   (1-beta-D-fructofuranosyl-(2->1)-)(m) alpha-D-glucopyranoside + (1-beta-
CA   D-fructofuranosyl-(2->1)-)(n+1) beta-D-fructofuranosyl-(2->6)-alpha-D-
CA   glucopyranoside (m > 0; n >= 0).
CC   -!- This enzyme catalyzes the transfer of the terminal (2->1)-linked
CC       beta-D-fructosyl group of a mono- or oligosaccharide substituent on
CC       O-1 of the fructose residue of sucrose onto O-6 of its glucose
CC       residue.
CC   -!- For example, if 1-kestose (1(F)-(beta-D-fructofuranosyl)sucrose) is
CC       both the donor and recipient in the reaction shown above, i.e., if m
CC       = 1 and n = 1, then the products will be sucrose and 6(G)-di-beta-D-
CC       fructofuranosylsucrose.
CC   -!- In this notation, the superscripts F and G are used to specify
CC       whether the fructose or glucose residue of the sucrose carries the
CC       substituent; alternatively, this may be indicated by the presence
CC       and/or absence of primes.
CC   -!- Sucrose cannot be a donor substrate in the reaction (i.e. m cannot be
CC       zero) and inulin cannot act as an acceptor.
CC   -!- Side reactions catalyzed are transfer of a beta-D-fructosyl group
CC       between compounds of the structure 1(F)-(1-beta-D-
CC       fructofuranosyl)(m)-6(G)-(1-beta-D-fructofuranosyl)(n) sucrose, where
CC       m >= 0 and n = 1 for the donor, and m >= 0 and n >= 0 for the
CC       acceptor.
PR   PROSITE; PDOC00532;
DR   P92916, GFT_ALLCE  ;  Q5FC15, GFT_ASPOF  ;
//
ID   2.4.1.244
DE   N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-
DE   acetylgalactosaminyltransferase.
AN   Beta-1,4-N-acetylgalactosaminyltransferase.
AN   Beta-4GalNAc-T3.
AN   Beta-4GalNAc-T4.
CA   UDP-N-acetyl-D-galactosamine + N-acetyl-beta-D-glucosaminyl group = UDP +
CA   N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl group.
CC   -!- The enzyme from human can transfer N-acetyl-D-galactosamine (GalNAc)
CC       to N-glycan and O-glycan substrates that have N-acetyl-D-glucosamine
CC       (GlcNAc) but not D-glucuronic acid (GlcUA) at their non-reducing end.
CC   -!- The N-acetyl-beta-D-glucosaminyl group is normally on a core
CC       oligosaccharide although benzyl glycosides have been used in enzyme-
CC       characterization experiments.
CC   -!- Some glycohormones, e.g. lutropin and thyrotropin contain the
CC       N-glycan structure containing the N-acetyl-beta-D-galactosaminyl-
CC       (1->4)-N-acetyl-beta-D-glucosaminyl group.
DR   Q6L9W6, B4GN3_HUMAN;  Q6L8S8, B4GN3_MOUSE;  Q76KP1, B4GN4_HUMAN;
DR   Q766D5, B4GN4_MOUSE;
//
ID   2.4.1.245
DE   Alpha,alpha-trehalose synthase.
AN   Trehalose synthase.
AN   Trehalose synthetase.
CA   ADP-glucose + D-glucose = alpha,alpha-trehalose + ADP.
CF   Magnesium.
CC   -!- The enzyme-catalyzed reaction is reversible.
CC   -!- In the reverse direction to that shown above, the enzyme is specific
CC       for alpha,alpha-trehalose as substrate, as it cannot use alpha- or
CC       beta-paranitrophenyl glucosides, maltose, sucrose, lactose or
CC       cellobiose.
CC   -!- While the enzyme from the hyperthermophilic archaeon Pyrococcus
CC       horikoshii can use ADP-, UDP- and GDP-glucose to the same extent,
CC       that from Thermococcus litoralis has a marked preference for ADP.
CC   -!- Formerly EC 2.4.1.n1.
DR   Q9HH00, TRET_PYRFU ;  O58762, TRET_PYRHO ;  Q1ARU5, TRET_RUBXD ;
DR   Q7LYW5, TRET_THELI ;
//
ID   2.4.1.246
DE   Mannosylfructose-phosphate synthase.
AN   Mannosylfructose-6-phosphate synthase.
AN   MFPS.
CA   GDP-mannose + D-fructose 6-phosphate = GDP + beta-D-fructofuranosyl-
CA   alpha-D-mannopyranoside 6(F)-phosphate.
CF   Manganese or magnesium.
CC   -!- GDP-mannose can be replaced by ADP-mannose but with a concomitant
CC       decrease in activity.
CC   -!- The product of this reaction is dephosphorylated by EC 3.1.3.79 to
CC       form the non-reducing disaccharide mannosylfructose, which is the
CC       major endogenous osmolyte produced by several alpha-proteobacteria in
CC       response to osmotic stress.
CC   -!- The F in the product name is used to indicate that the fructose
CC       residue of sucrose carries the substituent.
DR   A7TZT2, MFPS_AGRT5 ;
//
ID   2.4.1.247
DE   Beta-D-galactosyl-(1->4)-L-rhamnose phosphorylase.
AN   D-galactosyl-beta-1->4-L-rhamnose phosphorylase.
AN   GalRhaP.
CA   Beta-D-galactosyl-(1->4)-L-rhamnose + phosphate = L-rhamnose + alpha-D-
CA   galactose 1-phosphate.
CC   -!- The enzyme from Clostridium phytofermentans is also active toward
CC       toward beta-D-galactosyl derivatives of L-mannose, L-lyxose,
CC       D-glucose, 2-deoxy-D-glucose, and D-galactose in this order.
CC   -!- Differs from 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase
CC       (EC 2.4.1.211) in being active toward L-rhamnose and inactive toward
CC       N-acetyl hexosamine derivatives.
DR   A9KHK4, GLRP_CLOPH ;
//
ID   2.4.1.248
DE   Cycloisomaltooligosaccharide glucanotransferase.
CA   Cyclizes part of a (1->6)-alpha-D-glucan chain by formation of a (1->6)-
CA   alpha-D-glucosidic bond.
CC   -!- Specific for (1->6)-alpha-D-glucans (dextrans) and, unlike
CC       cyclomaltodextrin glucanotransferase (EC 2.4.1.19), without activity
CC       toward (1->4)-alpha-D-glucans, such as amylose.
CC   -!- It also has no activity on oligosaccharides, such as amylopectin and
CC       pullulan, containing (1->6)-alpha-D-glucosidic linkages at branch
CC       points.
CC   -!- The enzyme from Bacillus circulans T-3040 has been shown to form
CC       cycloisomalto-oligosaccharides of three sizes (7, 8 and 9 glucose
CC       units).
CC   -!- It will also catalyze the disproportionation of two isomalto-
CC       oligosaccharides molecules to yield a series of isomalto-
CC       oligosachharides and the addition of D-glucose to cycloisomalto-
CC       oligosaccharides with ring opening to form isomalto-oligosaccharides.
PR   PROSITE; PDOC51175;
DR   P94286, CTA1_BACCI ;  P70873, CTA2_BACCI ;
//
ID   2.4.1.249
DE   Delphinidin 3',5'-O-glucosyltransferase.
AN   UDP-glucose:anthocyanin 3',5'-O-glucosyltransferase.
CA   (1) UDP-glucose + delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside =
CA   UDP + delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside-3'-O-beta-D-
CA   glucoside.
CA   (2) UDP-glucose + delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside-3'-O-
CA   beta-D-glucoside = UDP + delphinidin 3-O-(6''-O-malonyl)-beta-D-
CA   glucoside-3',5'-di-O-beta-D-glucoside.
CC   -!- Ternatins are a group of polyacetylated delphinidin glucosides that
CC       confer blue color to the petals of butterfly pea (Clitoria ternatea).
CC   -!- This enzyme catalyzes two reactions in the biosynthesis of ternatin
CC       C5: the conversion of delphinidin 3-O-(6''-O-malonyl)-beta-D-
CC       glucoside to delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside-3'-O-
CC       beta-D-glucoside, followed by the conversion of the later to ternatin
CC       C5, by transferring two glucosyl groups in a stepwise manner.
//
ID   2.4.1.250
DE   D-inositol-3-phosphate glycosyltransferase.
AN   Mycothiol glycosyltransferase.
AN   N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase.
CA   UDP-N-acetyl-D-glucosamine + 1D-myo-inositol 3-phosphate = UDP + 1-O-
CA   (2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol 3-phosphate.
CC   -!- The enzyme, which belongs to the GT-B fold superfamily, catalyzes the
CC       first dedicated reaction in the biosynthesis of mycothiol.
CC   -!- The substrate was initially believed to be inositol, but eventually
CC       shown to be D-myo-inositol 3-phosphate.
CC   -!- A substantial conformational change occurs upon UDP binding, which
CC       generates the binding site for D-myo-inositol 3-phosphate.
CC   -!- Formerly EC 2.4.1.n3.
DR   C7Q4Y6, MSHA1_CATAD;  C7QKE8, MSHA2_CATAD;  A0LQY9, MSHA_ACIC1 ;
DR   C6WPK3, MSHA_ACTMD ;  A1R8N8, MSHA_ARTAT ;  B8HCF8, MSHA_ARTCA ;
DR   A0JZ09, MSHA_ARTS2 ;  D5UJ42, MSHA_CELFN ;  C3PK12, MSHA_CORA7 ;
DR   Q6NJL3, MSHA_CORDI ;  Q8FSH1, MSHA_COREF ;  A4QB40, MSHA_CORGB ;
DR   Q8NTA6, MSHA_CORGL ;  Q4JSW2, MSHA_CORJK ;  C4LLD6, MSHA_CORK4 ;
DR   B1VEI4, MSHA_CORU7 ;  Q0RS49, MSHA_FRAAA ;  Q2JFV0, MSHA_FRASC ;
DR   A8LDJ8, MSHA_FRASN ;  D2S4K7, MSHA_GEOOG ;  D0L476, MSHA_GORB4 ;
DR   C7R101, MSHA_JONDD ;  A6W6D9, MSHA_KINRD ;  D2Q1C4, MSHA_KRIFD ;
DR   A0QLK5, MSHA_MYCA1 ;  B1MHQ0, MSHA_MYCA9 ;  P64708, MSHA_MYCBO ;
DR   A1KFW0, MSHA_MYCBP ;  C1AKG4, MSHA_MYCBT ;  A4T324, MSHA_MYCGI ;
DR   B8ZT88, MSHA_MYCLB ;  P54138, MSHA_MYCLE ;  B2HQV2, MSHA_MYCMM ;
DR   Q73SU4, MSHA_MYCPA ;  A0QQZ8, MSHA_MYCS2 ;  A3PU84, MSHA_MYCSJ ;
DR   A1UAM8, MSHA_MYCSK ;  Q1BEA6, MSHA_MYCSS ;  A5TZL4, MSHA_MYCTA ;
DR   A5WJJ8, MSHA_MYCTF ;  C6DT68, MSHA_MYCTK ;  P64707, MSHA_MYCTU ;
DR   A0PVZ1, MSHA_MYCUA ;  A1T3B5, MSHA_MYCVP ;  C8XA09, MSHA_NAKMY ;
DR   D7AW65, MSHA_NOCDD ;  Q5YP47, MSHA_NOCFA ;  A1SP12, MSHA_NOCSJ ;
DR   C0ZUT0, MSHA_RHOE4 ;  C1AZ64, MSHA_RHOOB ;  Q0SF06, MSHA_RHOSR ;
DR   A4FQ08, MSHA_SACEN ;  C7MSY6, MSHA_SACVD ;  A8LZG1, MSHA_SALAI ;
DR   A4X1R6, MSHA_SALTO ;  D1BD84, MSHA_SANKS ;  D6Z995, MSHA_SEGRD ;
DR   D3Q051, MSHA_STANL ;  Q82G92, MSHA_STRAW ;  D7C367, MSHA_STRBB ;
DR   Q9FCG5, MSHA_STRCO ;  B1VS68, MSHA_STRGG ;  D2B9F4, MSHA_STRRD ;
DR   C9ZH13, MSHA_STRSW ;  D6Y4U7, MSHA_THEBD ;  D1A4Q3, MSHA_THECD ;
DR   Q47KS6, MSHA_THEFY ;  D5USX8, MSHA_TSUPD ;  D1BZ82, MSHA_XYLCX ;
//
ID   2.4.1.251
DE   GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-
DE   diphospho-di-trans,octa-cis-undecaprenol 4-beta-mannosyltransferase.
CA   GDP-mannose + GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-
CA   Glc-alpha-1-diphospho-di-trans,octa-cis-undecaprenol = GDP + D-Man-beta-
CA   (1->4)- GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-
CA   alpha-1-diphospho-di-trans,octa-cis-undecaprenol.
CC   -!- The enzyme is involved in the biosynthesis of the exopolysaccharide
CC       xanthan.
//
ID   2.4.1.252
DE   GDP-mannose:cellobiosyl-diphosphopolyprenol alpha-mannosyltransferase.
CA   GDP-mannose + D-Glc-beta-(1->4)-Glc-alpha-1-diphospho-di-trans,octa-
CA   cis-undecaprenol = GDP + D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-
CA   alpha-1-diphospho-di-trans,octa-cis-undecaprenol.
CC   -!- In the bacterium Gluconacetobacter xylinus (previously known as
CC       Acetobacter xylinum) the enzyme is involved in the biosynthesis of
CC       the exopolysaccharide acetan.
CC   -!- In Xanthomonas campestris the enzyme is involved in the biosynthesis
CC       of the exopolysaccharide xanthan.
//
ID   2.4.1.253
DE   Baicalein 7-O-glucuronosyltransferase.
AN   UBGAT.
CA   UDP-D-glucuronate + baicalein = UDP + baicalin.
CC   -!- The enzyme is specific for UDP-D-glucuronate as a sugar donor and
CC       flavones with substitution ortho- to the 7-OH group such as baicalein
CC       (6-OH), scutellarein (6-OH) and wogonin (8-OMe).
DR   Q76MR7, UBGAT_SCUBA;
//
ID   2.4.1.254
DE   Cyanidin-3-O-glucoside 2-O-glucuronosyltransferase.
CA   UDP-D-glucuronate + cyanidin 3-O-beta-D-glucoside = UDP + cyanidin 3-O-
CA   (2-O-beta-D-glucuronosyl)-beta-D-glucoside.
CC   -!- The enzyme is highly specific for cyanidin 3-O-glucosides and UDP-D-
CC       glucuronate.
CC   -!- Involved in the production of glucuronosylated anthocyanins that are
CC       the origin of the red coloration of flowers of Bellis perennis.
PR   PROSITE; PDOC00359;
DR   Q5NTH0, UGAT_BELPE ;
//
ID   2.4.1.255
DE   Protein O-GlcNAc transferase.
AN   O-linked N-acetylglucosaminyltransferase.
AN   OGTase.
CA   (1) UDP-N-acetyl-D-glucosamine + [protein]-L-serine = UDP + [protein]-3-
CA   O-(N-acetyl-D-glucosaminyl)-L-serine.
CA   (2) UDP-N-acetyl-D-glucosamine + [protein]-L-threonine = UDP + [protein]-
CA   3-O-(N-acetyl-D-glucosaminyl)-L-threonine.
CC   -!- Within higher eukaryotes post-translational modification of protein
CC       serines/threonines with N-acetylglucosamine (O-GlcNAc) is dynamic,
CC       inducible and abundant, regulating many cellular processes by
CC       interfering with protein phosphorylation.
CC   -!- EC 2.4.1.255 transfers GlcNAc onto substrate proteins and
CC       EC 3.2.1.169 cleaves GlcNAc from the modified proteins.
//
ID   2.4.1.256
DE   Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase.
CA   Dolichyl beta-D-glucosyl phosphate + D-Glc-alpha-(1->3)-D-Glc-alpha-
CA   (1->3)-D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-
CA   alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->2)-D-Man-alpha-(1->6))-
CA   D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-
CA   diphosphodolichol = D-Glc-alpha-(1->2)-D-Glc-alpha-(1->3)-D-Glc-alpha-
CA   (1->3)-D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-
CA   alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->2)-D-Man-alpha-(1->6))-
CA   D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-
CA   diphosphodolichol + dolichyl phosphate.
CC   -!- This enzyme performs the final step in the synthesis of the lipid-
CC       linked oligosaccharide attaching D-glucose in an alpha-1,2-linkage to
CC       the outermost D-glucose in the long branch.
DR   Q5BKT4, AG10A_HUMAN;  Q5I7T1, AG10B_HUMAN;  Q3UGP8, AG10B_MOUSE;
DR   O88788, AG10B_RAT  ;  Q75AQ8, ALG10_ASHGO;  Q4X162, ALG10_ASPFU;
DR   Q59YV2, ALG10_CANAL;  Q6FL34, ALG10_CANGA;  Q6BW42, ALG10_DEBHA;
DR   Q5B0M8, ALG10_EMENI;  Q4HZE0, ALG10_GIBZE;  Q6CN27, ALG10_KLULA;
DR   P0C147, ALG10_MAGO7;  Q7SA35, ALG10_NEUCR;  Q10254, ALG10_SCHPO;
DR   Q4P2W6, ALG10_USTMA;  Q6CEA5, ALG10_YARLI;  P50076, ALG10_YEAST;
//
ID   2.4.1.257
DE   GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase.
CA   GDP-D-mannose + D-Man-alpha-(1->3)-D-Man-beta-(1->4)-D-GlcNAc-beta-
CA   (1->4)-D-GlcNAc-diphosphodolichol = GDP + D-Man-alpha-(1->3)-(D-Man-
CA   alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-
CA   diphosphodolichol.
CC   -!- The biosynthesis of asparagine-linked glycoproteins utilizes a
CC       dolichyl diphosphate-linked glycosyl donor, which is assembled by the
CC       series of membrane-bound glycosyltransferases that comprise the
CC       dolichol pathway.
CC   -!- Alg2 mannosyltransferase from Saccharomyces cerevisiae carries out an
CC       alpha-1,3-mannosylation (cf. EC 2.4.1.132) of D-Man-beta-(1->4)-D-
CC       GlcNAc-beta-(1->4)-GlcNAc-diphosphodolichol, followed by an alpha-
CC       1,6-mannosylation, to form the first branched pentasaccharide
CC       intermediate of the dolichol pathway.
DR   Q755C1, ALG2_ASHGO ;  Q59LF2, ALG2_CANAL ;  Q6FJJ9, ALG2_CANGA ;
DR   Q6BVA4, ALG2_DEBHA ;  Q7KWM5, ALG2_DICDI ;  Q9H553, ALG2_HUMAN ;
DR   Q6CWQ0, ALG2_KLULA ;  Q9DBE8, ALG2_MOUSE ;  Q8X0H8, ALG2_NEUCR ;
DR   O94738, ALG2_RHIPU ;  Q96WW6, ALG2_SCHPO ;  Q6C3V7, ALG2_YARLI ;
DR   P43636, ALG2_YEAST ;
//
ID   2.4.1.258
DE   Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase.
AN   Alg3 alpha-1,3-mannosyl transferase.
AN   Man(5)GlcNAc(2)-PP-Dol mannosyltransferase.
CA   Dolichyl beta-D-mannosyl phosphate + D-Man-alpha-(1->2)-D-Man-alpha-
CA   (1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-
CA   GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol = D-Man-alpha-(1->2)-D-Man-
CA   alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->3)-D-Man-alpha-(1->6))-
CA   D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol +
CA   dolichyl phosphate.
CC   -!- The formation of N-glycosidic linkages of glycoproteins involves the
CC       ordered assembly of the common Glc(3)Man(9)GlcNAc(2) core-
CC       oligosaccharide on the lipid carrier dolichyl diphosphate.
CC   -!- Early mannosylation steps occur on the cytoplasmic side of the
CC       endoplasmic reticulum with GDP-Man as donor, the final reactions from
CC       Man(5)GlcNAc(2)-PP-Dol to Man(9)Glc-NAc(2)-PP-Dol on the lumenal side
CC       use dolichyl beta-D-mannosyl phosphate.
CC   -!- The first step of this assembly pathway on the luminal side of the
CC       endoplasmic reticulum is catalyzed by ALG3.
CC   -!- Formerly EC 2.4.1.130.
DR   O82244, ALG3_ARATH ;  Q751K5, ALG3_ASHGO ;  A1CBE6, ALG3_ASPCL ;
DR   Q4WVG2, ALG3_ASPFU ;  A2RA94, ALG3_ASPNC ;  Q2U6A4, ALG3_ASPOR ;
DR   Q6FXS2, ALG3_CANGA ;  P0CN93, ALG3_CRYNB ;  P0CN92, ALG3_CRYNJ ;
DR   Q6BYY8, ALG3_DEBHA ;  Q55F69, ALG3_DICDI ;  Q92685, ALG3_HUMAN ;
DR   Q6CMF1, ALG3_KLULA ;  Q8K2A8, ALG3_MOUSE ;  A1DDZ3, ALG3_NEOFI ;
DR   Q9C1K8, ALG3_NEUCR ;  Q0TVF9, ALG3_PHANO ;  A5DJQ5, ALG3_PICGU ;
DR   Q6DNA2, ALG3_PICPG ;  A3LTB7, ALG3_PICST ;  Q9Y7I4, ALG3_SCHPO ;
DR   P38179, ALG3_YEAST ;
//
ID   2.4.1.259
DE   Dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase.
CA   Dolichyl beta-D-mannosyl phosphate + D-Man-alpha-(1->2)-D-Man-alpha-
CA   (1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->3)-D-Man-alpha-(1->6))-D-Man-
CA   beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol = D-Man-
CA   alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->2)-D-
CA   Man-alpha-(1->3)-D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-
CA   (1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.
CC   -!- The formation of N-glycosidic linkages of glycoproteins involves the
CC       ordered assembly of the common Glc(3)Man(9)GlcNAc(2) core-
CC       oligosaccharide on the lipid carrier dolichyl diphosphate.
CC   -!- Early mannosylation steps occur on the cytoplasmic side of the
CC       endoplasmic reticulum with GDP-Man as donor, the final reactions from
CC       Man(5)GlcNAc(2)-PP-Dol to Man(9)Glc-NAc(2)-PP-Dol on the lumenal side
CC       use dolichyl beta-D-mannosyl phosphate.
CC   -!- ALG9 mannosyltransferase catalyzes the addition of two different
CC       alpha-1,2-mannose residues - the addition of alpha-1,2-mannose to
CC       Man(6)GlcNAc(2)-PP-Dol (EC 2.4.1.259) and the addition of alpha-1,2-
CC       mannose to Man(8)GlcNAc(2)-PP-Dol (EC 2.4.1.261).
CC   -!- Formerly EC 2.4.1.130.
DR   Q9FZ49, ALG9_ARATH ;  Q9H6U8, ALG9_HUMAN ;  Q8VDI9, ALG9_MOUSE ;
DR   P53868, ALG9_YEAST ;
//
ID   2.4.1.260
DE   Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase.
AN   Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl alpha-6-mannosyltransferase.
CA   Dolichyl beta-D-mannosyl phosphate + D-Man-alpha-(1->2)-D-Man-alpha-
CA   (1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-D-Man-
CA   alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-
CA   diphosphodolichol = D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-
CA   (1->3)-(D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-
CA   alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-
CA   diphosphodolichol + dolichyl phosphate.
CC   -!- The formation of N-glycosidic linkages of glycoproteins involves the
CC       ordered assembly of the common Glc(3)Man(9)GlcNAc(2) core-
CC       oligosaccharide on the lipid carrier dolichyl diphosphate.
CC   -!- Early mannosylation steps occur on the cytoplasmic side of the
CC       endoplasmic reticulum with GDP-Man as donor, the final reactions from
CC       Man(5)GlcNAc(2)-PP-Dol to Man(9)Glc-NAc(2)-PP-Dol on the lumenal side
CC       use dolichyl beta-D-mannosyl phosphate.
CC   -!- Formerly EC 2.4.1.130.
DR   A8MR93, ALG12_ARATH;  Q23361, ALG12_CAEEL;  Q9VH78, ALG12_DROME;
DR   Q9BV10, ALG12_HUMAN;  Q8VDB2, ALG12_MOUSE;  Q9USD4, ALG12_SCHPO;
DR   P53730, ALG12_YEAST;
//
ID   2.4.1.261
DE   Dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase.
CA   Dolichyl beta-D-mannosyl phosphate + D-Man-alpha-(1->2)-D-Man-alpha-
CA   (1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-
CA   alpha-(1->6))-D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-
CA   D-GlcNAc-diphosphodolichol = D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-
CA   alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->2)-
CA   D-Man-alpha-(1->6))-D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-
CA   (1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.
CC   -!- The formation of N-glycosidic linkages of glycoproteins involves the
CC       ordered assembly of the common Glc(3)Man(9)GlcNAc(2) core-
CC       oligosaccharide on the lipid carrier dolichyl diphosphate.
CC   -!- Early mannosylation steps occur on the cytoplasmic side of the
CC       endoplasmic reticulum with GDP-Man as donor, the final reactions from
CC       Man(5)GlcNAc(2)-PP-Dol to Man(9)Glc-NAc(2)-PP-Dol on the lumenal side
CC       use dolichyl beta-D-mannosyl phosphate.
CC   -!- ALG9 mannosyltransferase catalyzes the addition of two different
CC       alpha-1,2-mannose residues - the addition of alpha-1,2-mannose to
CC       Man(6)GlcNAc(2)-PP-Dol (EC 2.4.1.259) and the addition of alpha-1,2-
CC       mannose to Man(8)GlcNAc(2)-PP-Dol (EC 2.4.1.261).
CC   -!- Formerly EC 2.4.1.130.
DR   Q9FZ49, ALG9_ARATH ;  Q9H6U8, ALG9_HUMAN ;  Q8VDI9, ALG9_MOUSE ;
DR   P53868, ALG9_YEAST ;
//
ID   2.4.1.262
DE   Soyasapogenol glucuronosyltransferase.
CA   UDP-glucuronate + soyasapogenol B = UDP + soyasapogenol B 3-O-
CA   D-glucuronide.
CF   Magnesium.
CC   -!- Requires a divalent ion, Mg(2+) better than Mn(2+), better than
CC       Ca(2+).
CC   -!- Also acts on soysapogenol A and E.
//
ID   2.4.1.263
DE   Abscisate beta-glucosyltransferase.
AN   ABA-glucosyltransferase.
AN   ABA-GTase.
CA   UDP-D-glucose + abscisate = UDP + beta-D-glucopyranosyl abscisate.
CC   -!- The enzyme acts better on (S)-2-trans-abscisate than the natural (S)-
CC       2-cis isomer, abscisate, or its enantiomer, the (R)-2-cis isomer.
DR   Q8W3P8, AOG_PHAAN  ;
//
ID   2.4.1.n1
DE   Transferred entry: 2.4.1.245.
//
ID   2.4.1.n2
DE   Loliose synthase.
CA   UDP-galactose + sucrose = UDP + loliose.
//
ID   2.4.1.n3
DE   Transferred entry: 2.4.1.250.
//
ID   2.4.1.n4
DE   Transferred entry: 2.4.1.131.
//
ID   2.4.2.1
DE   Purine-nucleoside phosphorylase.
AN   Inosine phosphorylase.
AN   PNPase.
CA   Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate.
CC   -!- Specificity not completely determined.
CC   -!- Can also catalyze ribosyltransferase reactions of the type catalyzed
CC       by EC 2.4.2.5.
PR   PROSITE; PDOC00946;
PR   PROSITE; PDOC00954;
DR   Q6LUH1, DEOD1_PHOPR;  Q8EKK0, DEOD1_SHEON;  Q9KPM0, DEOD1_VIBCH;
DR   Q5E7J4, DEOD1_VIBF1;  Q87M25, DEOD1_VIBPA;  Q8DBS9, DEOD1_VIBVU;
DR   Q7MI41, DEOD1_VIBVY;  Q6LLA7, DEOD2_PHOPR;  Q8EHK0, DEOD2_SHEON;
DR   Q9KNB2, DEOD2_VIBCH;  Q5E0H4, DEOD2_VIBF1;  Q87G42, DEOD2_VIBPA;
DR   Q8D3Z2, DEOD2_VIBVU;  Q7MFG6, DEOD2_VIBVY;  Q8EDM4, DEOD3_SHEON;
DR   Q5DYV8, DEOD3_VIBF1;  A3N122, DEOD_ACTP2 ;  B3H1P6, DEOD_ACTP7 ;
DR   B0BPV3, DEOD_ACTPJ ;  P94164, DEOD_ACTPL ;  A6VM01, DEOD_ACTSZ ;
DR   B6ER81, DEOD_ALISL ;  A6TVU0, DEOD_ALKMQ ;  B7GKU4, DEOD_ANOFW ;
DR   A7Z5M8, DEOD_BACA2 ;  C3P552, DEOD_BACAA ;  C3L9J6, DEOD_BACAC ;
DR   A0RBS0, DEOD_BACAH ;  Q81T09, DEOD_BACAN ;  B7JGU6, DEOD_BACC0 ;
DR   Q73B32, DEOD_BACC1 ;  B7IP41, DEOD_BACC2 ;  C1EMV9, DEOD_BACC3 ;
DR   B7HHL7, DEOD_BACC4 ;  B7HKX2, DEOD_BACC7 ;  Q5EEL8, DEOD_BACCE ;
DR   A7GN01, DEOD_BACCN ;  B9IVI6, DEOD_BACCQ ;  Q81FV5, DEOD_BACCR ;
DR   Q63DR9, DEOD_BACCZ ;  Q6HL92, DEOD_BACHK ;  Q65IE9, DEOD_BACLD ;
DR   O34925, DEOD_BACSU ;  A9VLN1, DEOD_BACWK ;  C0ZDZ3, DEOD_BREBN ;
DR   B8D9W3, DEOD_BUCA5 ;  P57606, DEOD_BUCAI ;  Q8K937, DEOD_BUCAP ;
DR   B8D865, DEOD_BUCAT ;  Q89A58, DEOD_BUCBP ;  Q7NRT2, DEOD_CHRVO ;
DR   A8ALX7, DEOD_CITK8 ;  A6M0X2, DEOD_CLOB8 ;  A0Q1A0, DEOD_CLONN ;
DR   Q0TQJ7, DEOD_CLOP1 ;  Q0ST47, DEOD_CLOPS ;  Q894Z3, DEOD_CLOTE ;
DR   Q483Q8, DEOD_COLP3 ;  A5EV41, DEOD_DICNV ;  A8LJI8, DEOD_DINSH ;
DR   A7ZVS7, DEOD_ECO24 ;  B7UR12, DEOD_ECO27 ;  B7MNJ1, DEOD_ECO45 ;
DR   B7LEN0, DEOD_ECO55 ;  P0ABP9, DEOD_ECO57 ;  B5Z4R6, DEOD_ECO5E ;
DR   B7NW64, DEOD_ECO7I ;  B7N2V8, DEOD_ECO81 ;  B7LXU6, DEOD_ECO8A ;
DR   C4ZT66, DEOD_ECOBW ;  B1XFJ4, DEOD_ECODH ;  A8A8B3, DEOD_ECOHS ;
DR   Q0T8S9, DEOD_ECOL5 ;  Q8FA51, DEOD_ECOL6 ;  B1IS35, DEOD_ECOLC ;
DR   P0ABP8, DEOD_ECOLI ;  B7NH52, DEOD_ECOLU ;  B6I6N1, DEOD_ECOSE ;
DR   B1LEI9, DEOD_ECOSM ;  C5BHJ5, DEOD_EDWI9 ;  A4W6A1, DEOD_ENT38 ;
DR   A7MIG7, DEOD_ENTS8 ;  Q6D989, DEOD_ERWCT ;  B2VH53, DEOD_ERWT9 ;
DR   B7LNS4, DEOD_ESCF3 ;  B1YJP1, DEOD_EXIS2 ;  C4L2Y4, DEOD_EXISA ;
DR   Q5KZM1, DEOD_GEOKA ;  P77835, DEOD_GEOSE ;  C5D2F9, DEOD_GEOSW ;
DR   A4IN93, DEOD_GEOTN ;  Q7VMS8, DEOD_HAEDU ;  Q4QN30, DEOD_HAEI8 ;
DR   A5U9X5, DEOD_HAEIE ;  A5UH23, DEOD_HAEIG ;  P44417, DEOD_HAEIN ;
DR   B8F672, DEOD_HAEPS ;  Q0I1K5, DEOD_HAES1 ;  B0UVM2, DEOD_HAES2 ;
DR   Q2SHN2, DEOD_HAHCH ;  Q17YP0, DEOD_HELAH ;  B6JN17, DEOD_HELP2 ;
DR   B5Z8H2, DEOD_HELPG ;  Q1CS88, DEOD_HELPH ;  Q9ZK38, DEOD_HELPJ ;
DR   B2UUU1, DEOD_HELPS ;  P56463, DEOD_HELPY ;  Q28U96, DEOD_JANSC ;
DR   B5Y274, DEOD_KLEP3 ;  Q59482, DEOD_KLEPN ;  Q03Q52, DEOD_LACBA ;
DR   Q03CD2, DEOD_LACC3 ;  B3W8N4, DEOD_LACCB ;  Q9CH10, DEOD_LACLA ;
DR   O32810, DEOD_LACLM ;  Q02ZT0, DEOD_LACLS ;  A5VHR2, DEOD_LACRD ;
DR   B2G592, DEOD_LACRJ ;  Q38XI0, DEOD_LACSS ;  Q92AF2, DEOD_LISIN ;
DR   C1KWF5, DEOD_LISMC ;  Q71YG0, DEOD_LISMF ;  B8DDP6, DEOD_LISMH ;
DR   Q8Y644, DEOD_LISMO ;  A0AJW1, DEOD_LISW6 ;  Q65RA4, DEOD_MANSM ;
DR   P47295, DEOD_MYCGE ;  P47724, DEOD_MYCPI ;  P75053, DEOD_MYCPN ;
DR   Q1D9Z7, DEOD_MYXXD ;  Q8ENY0, DEOD_OCEIH ;  Q9CLE6, DEOD_PASMU ;
DR   C6DKM0, DEOD_PECCP ;  Q7N930, DEOD_PHOLL ;  B4EWA1, DEOD_PROMH ;
DR   Q3ICU8, DEOD_PSEHT ;  A1SYK4, DEOD_PSYIN ;  Q169T2, DEOD_ROSDO ;
DR   B5F527, DEOD_SALA4 ;  A9MRA4, DEOD_SALAR ;  Q57G38, DEOD_SALCH ;
DR   B5FTC8, DEOD_SALDC ;  B5R2J9, DEOD_SALEP ;  B5R9V2, DEOD_SALG2 ;
DR   B4TH02, DEOD_SALHS ;  B4T4H3, DEOD_SALNS ;  Q5PK20, DEOD_SALPA ;
DR   A9N7E3, DEOD_SALPB ;  B5BAK0, DEOD_SALPK ;  B4TU44, DEOD_SALSV ;
DR   Q8Z0U2, DEOD_SALTI ;  Q8ZJV7, DEOD_SALTY ;  A1S477, DEOD_SHEAM ;
DR   B8E6P7, DEOD_SHEB2 ;  A3D7J1, DEOD_SHEB5 ;  A6WRB5, DEOD_SHEB8 ;
DR   Q12QG0, DEOD_SHEDO ;  Q086F7, DEOD_SHEFN ;  A3QGT0, DEOD_SHELP ;
DR   Q0HLE7, DEOD_SHESM ;  Q0HXQ1, DEOD_SHESR ;  B2TZR7, DEOD_SHIB3 ;
DR   Q31SV5, DEOD_SHIBS ;  Q327L2, DEOD_SHIDS ;  Q0SX27, DEOD_SHIF8 ;
DR   Q83P00, DEOD_SHIFL ;  Q3YU09, DEOD_SHISS ;  A8AXN4, DEOD_STRGC ;
DR   Q04L76, DEOD_STRP2 ;  B5E3K8, DEOD_STRP4 ;  C1C6H0, DEOD_STRP7 ;
DR   Q1JC85, DEOD_STRPB ;  Q1JM69, DEOD_STRPC ;  Q1J733, DEOD_STRPF ;
DR   A2RF09, DEOD_STRPG ;  B1IB05, DEOD_STRPI ;  B8ZNN8, DEOD_STRPJ ;
DR   B2INV3, DEOD_STRPS ;  A4W2M2, DEOD_STRS2 ;  A4VWC2, DEOD_STRSY ;
DR   Q03KK1, DEOD_STRTD ;  Q56037, DEOD_STRTR ;  B9DUK0, DEOD_STRU0 ;
DR   C1CDI3, DEOD_STRZJ ;  C1CJS5, DEOD_STRZP ;  C1CS55, DEOD_STRZT ;
DR   B0K889, DEOD_THEP3 ;  B0K6Y4, DEOD_THEPX ;  Q8R973, DEOD_THETN ;
DR   C4LAY8, DEOD_TOLAT ;  O83716, DEOD_TREPA ;  Q8KRT5, DEOD_XENNA ;
DR   A1JJA0, DEOD_YERE8 ;  A7FMH2, DEOD_YERP3 ;  Q1C166, DEOD_YERPA ;
DR   B2K3J1, DEOD_YERPB ;  Q8ZIQ2, DEOD_YERPE ;  A9R046, DEOD_YERPG ;
DR   Q1CMY7, DEOD_YERPN ;  A4TQJ0, DEOD_YERPP ;  Q66EV7, DEOD_YERPS ;
DR   B1JL34, DEOD_YERPY ;  P55859, PNPH_BOVIN ;  P00491, PNPH_HUMAN ;
DR   P23492, PNPH_MOUSE ;  P85973, PNPH_RAT   ;  Q9UTG1, PNPH_SCHPO ;
DR   Q05788, PNPH_YEAST ;  P46354, PUNA_BACSU ;  P81989, PUNA_CELSP ;
DR   P77834, PUNA_GEOSE ;  P0A539, PUNA_MYCBO ;  P46862, PUNA_MYCLE ;
DR   P0A538, PUNA_MYCTU ;
//
ID   2.4.2.2
DE   Pyrimidine-nucleoside phosphorylase.
AN   Py-NPase.
CA   A pyrimidine nucleoside + phosphate = a pyrimidine base + alpha-D-ribose
CA   1-phosphate.
CC   -!- Both uridine and thymidine are substrates.
PR   PROSITE; PDOC00557;
DR   P39142, PDP_BACSU  ;  P77836, PDP_GEOSE  ;  Q2FEZ3, PDP_STAA3  ;
DR   Q2FWC1, PDP_STAA8  ;  Q2YUL7, PDP_STAAB  ;  Q5HE64, PDP_STAAC  ;
DR   Q99SC3, PDP_STAAM  ;  Q7A4D0, PDP_STAAN  ;  Q6GET9, PDP_STAAR  ;
DR   Q6G7H4, PDP_STAAS  ;  Q8NVF6, PDP_STAAW  ;  Q5HM85, PDP_STAEQ  ;
DR   Q8CNH8, PDP_STAES  ;  Q4L818, PDP_STAHJ  ;
//
ID   2.4.2.3
DE   Uridine phosphorylase.
AN   Pyrimidine phosphorylase.
AN   UPase.
AN   UrdPase.
CA   Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.
PR   PROSITE; PDOC00946;
DR   P12758, UDP_ECOLI  ;  O08444, UDP_ENTAE  ;  P43770, UDP_HAEIN  ;
DR   P52671, UDP_KLEPN  ;  P19662, UDP_LACRH  ;  P0A1F7, UDP_SALTI  ;
DR   P0A1F6, UDP_SALTY  ;  O83990, UDP_TREPA  ;  Q16831, UPP1_HUMAN ;
DR   P52624, UPP1_MOUSE ;  O95045, UPP2_HUMAN ;  Q8CGR7, UPP2_MOUSE ;
//
ID   2.4.2.4
DE   Thymidine phosphorylase.
AN   Pyrimidine phosphorylase.
CA   Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.
CC   -!- In some tissues also catalyzes deoxyribosyltransferase reactions of
CC       the type catalyzed by EC 2.4.2.6.
PR   PROSITE; PDOC00557;
DR   A8IA58, RBKTP_AZOC5;  Q0K3R9, RBKTP_CUPNH;  Q46UT0, RBKTP_CUPPJ;
DR   B2AIF3, RBKTP_CUPTR;  Q16A32, RBKTP_ROSDO;  A1W631, TYPH1_ACISJ;
DR   O28928, TYPH1_ARCFU;  Q0KA59, TYPH1_CUPNH;  A1W9B0, TYPH2_ACISJ;
DR   O28927, TYPH2_ARCFU;  Q46S32, TYPH2_CUPPJ;  A0KPE3, TYPH_AERHH ;
DR   A4SRU3, TYPH_AERS4 ;  Q8UJ08, TYPH_AGRT5 ;  B6ENG4, TYPH_ALISL ;
DR   Q89QK7, TYPH_BRAJA ;  A5EG87, TYPH_BRASB ;  A4YRL1, TYPH_BRASO ;
DR   Q1BV59, TYPH_BURCA ;  B1KC83, TYPH_BURCC ;  A0KCQ9, TYPH_BURCH ;
DR   B4EPB7, TYPH_BURCJ ;  A3MAQ6, TYPH_BURM7 ;  Q62EC5, TYPH_BURMA ;
DR   A1UY21, TYPH_BURMS ;  A3P8N2, TYPH_BURP0 ;  A3NN77, TYPH_BURP6 ;
DR   Q63IV6, TYPH_BURPS ;  Q39PA6, TYPH_BURS3 ;  Q7NRT0, TYPH_CHRVO ;
DR   Q483R6, TYPH_COLP3 ;  A7ZVS5, TYPH_ECO24 ;  B7UR10, TYPH_ECO27 ;
DR   B7MNI9, TYPH_ECO45 ;  B7LEM8, TYPH_ECO55 ;  Q8XB35, TYPH_ECO57 ;
DR   B5Z4R4, TYPH_ECO5E ;  B7NW62, TYPH_ECO7I ;  B7MTC8, TYPH_ECO81 ;
DR   B7LXU4, TYPH_ECO8A ;  B1XFJ2, TYPH_ECODH ;  A8A8B1, TYPH_ECOHS ;
DR   Q8FA52, TYPH_ECOL6 ;  B1IS37, TYPH_ECOLC ;  P07650, TYPH_ECOLI ;
DR   B7NH50, TYPH_ECOLU ;  B6I6M9, TYPH_ECOSE ;  B1LEI7, TYPH_ECOSM ;
DR   A4W699, TYPH_ENT38 ;  A7MGA9, TYPH_ENTS8 ;  Q6D991, TYPH_ERWCT ;
DR   B2VH51, TYPH_ERWT9 ;  B7LNS2, TYPH_ESCF3 ;  Q2SLV0, TYPH_HAHCH ;
DR   P19971, TYPH_HUMAN ;  A2BJU0, TYPH_HYPBU ;  Q5QXT8, TYPH_IDILO ;
DR   B5Y276, TYPH_KLEP3 ;  A6THZ7, TYPH_KLEP7 ;  P19663, TYPH_LACRH ;
DR   Q5X2M8, TYPH_LEGPA ;  A5IFN1, TYPH_LEGPC ;  Q5ZWR3, TYPH_LEGPH ;
DR   Q8RNP4, TYPH_LEGPN ;  Q0ATA0, TYPH_MARMM ;  Q11BH8, TYPH_MESSB ;
DR   A6UUN0, TYPH_META3 ;  Q8TL01, TYPH_METAC ;  A7I5N0, TYPH_METB6 ;
DR   Q466X0, TYPH_METBF ;  Q12Z64, TYPH_METBU ;  Q607P2, TYPH_METCA ;
DR   Q2FTS5, TYPH_METHJ ;  Q58081, TYPH_METJA ;  A2SPI9, TYPH_METLZ ;
DR   A4FZL0, TYPH_METM5 ;  A9A6M7, TYPH_METM6 ;  A6VIW6, TYPH_METM7 ;
DR   Q8Q0P9, TYPH_METMA ;  A3CSY4, TYPH_METMJ ;  Q6M0E4, TYPH_METMP ;
DR   A0B6C9, TYPH_METTP ;  A6URW3, TYPH_METVS ;  Q99N42, TYPH_MOUSE ;
DR   P47297, TYPH_MYCGE ;  P43050, TYPH_MYCHO ;  P47717, TYPH_MYCPI ;
DR   P75052, TYPH_MYCPN ;  O53366, TYPH_MYCTU ;  Q3IP82, TYPH_NATPD ;
DR   Q1QM39, TYPH_NITHX ;  A7HYS8, TYPH_PARL1 ;  Q6LUH3, TYPH_PHOPR ;
DR   Q12E97, TYPH_POLSJ ;  B4EWA3, TYPH_PROMH ;  A4VHV6, TYPH_PSEU5 ;
DR   A1SYK5, TYPH_PSYIN ;  Q9V163, TYPH_PYRAB ;  Q8U0I2, TYPH_PYRFU ;
DR   O59251, TYPH_PYRHO ;  Q5JCX3, TYPH_PYRKO ;  Q8Y2X7, TYPH_RALSO ;
DR   Q5FVR2, TYPH_RAT   ;  Q98GV5, TYPH_RHILO ;  Q92T50, TYPH_RHIME ;
DR   C3MBH0, TYPH_RHISN ;  Q21W90, TYPH_RHOFD ;  Q07J10, TYPH_RHOP5 ;
DR   Q6N2A3, TYPH_RHOPA ;  Q20Z21, TYPH_RHOPB ;  Q13B59, TYPH_RHOPS ;
DR   B3QKL9, TYPH_RHOPT ;  B5F525, TYPH_SALA4 ;  A9MRA6, TYPH_SALAR ;
DR   Q57G40, TYPH_SALCH ;  B5FTC6, TYPH_SALDC ;  B5R2J7, TYPH_SALEP ;
DR   B5R9V0, TYPH_SALG2 ;  B4TH00, TYPH_SALHS ;  B4T4H1, TYPH_SALNS ;
DR   Q5PK22, TYPH_SALPA ;  B5BAJ8, TYPH_SALPK ;  B4TU42, TYPH_SALSV ;
DR   Q8XF46, TYPH_SALTI ;  Q7CP66, TYPH_SALTY ;  A8G9H7, TYPH_SERP5 ;
DR   A1S475, TYPH_SHEAM ;  B8E6P5, TYPH_SHEB2 ;  A3D7J3, TYPH_SHEB5 ;
DR   A6WRB7, TYPH_SHEB8 ;  A9KZ79, TYPH_SHEB9 ;  Q12QG2, TYPH_SHEDO ;
DR   Q086F9, TYPH_SHEFN ;  B0TQ90, TYPH_SHEHH ;  A3QGT2, TYPH_SHELP ;
DR   Q8EHK3, TYPH_SHEON ;  A8H727, TYPH_SHEPA ;  A4Y9A7, TYPH_SHEPC ;
DR   B8CKI5, TYPH_SHEPW ;  A0KU08, TYPH_SHESA ;  A8FYQ8, TYPH_SHESH ;
DR   Q0HLE9, TYPH_SHESM ;  Q0HXQ3, TYPH_SHESR ;  A1RH88, TYPH_SHESW ;
DR   B1KRP7, TYPH_SHEWM ;  B2TZR5, TYPH_SHIB3 ;  Q31SV7, TYPH_SHIBS ;
DR   Q327L4, TYPH_SHIDS ;  Q0SX29, TYPH_SHIF8 ;  Q83P01, TYPH_SHIFL ;
DR   Q3YU11, TYPH_SHISS ;  A6UET3, TYPH_SINMW ;  Q2NW05, TYPH_SODGM ;
DR   Q1GQ92, TYPH_SPHAL ;  C5A1L9, TYPH_THEGJ ;  B6YWT7, TYPH_THEON ;
DR   A1RWC3, TYPH_THEPD ;  C6A2A0, TYPH_THESM ;  C4LAA1, TYPH_TOLAT ;
DR   Q0W5A8, TYPH_UNCMA ;  Q9KPL8, TYPH_VIBCH ;  Q5E7J6, TYPH_VIBF1 ;
DR   B5FA99, TYPH_VIBFM ;  Q87M23, TYPH_VIBPA ;  Q8DBT1, TYPH_VIBVU ;
DR   Q7MI39, TYPH_VIBVY ;  A1JJ98, TYPH_YERE8 ;  A7FMH4, TYPH_YERP3 ;
DR   Q74PY8, TYPH_YERPE ;  Q66EV9, TYPH_YERPS ;  B1JL36, TYPH_YERPY ;
//
ID   2.4.2.5
DE   Nucleoside ribosyltransferase.
CA   D-ribosyl-base(1) + base(2) = D-ribosyl-base(2) + base(1).
CC   -!- Base(1) and base(2) represent various purines and pyrimidines.
//
ID   2.4.2.6
DE   Nucleoside deoxyribosyltransferase.
CA   2-deoxy-D-ribosyl-base(1) + base(2) = 2-deoxy-D-ribosyl-base(2) +
CA   base(1).
CC   -!- Base(1) and base(2) represent various purines and pyrimidines.
DR   Q6YNI5, NTD_LACFE  ;  Q74LQ9, NTD_LACJO  ;  Q9R5V5, NTD_LACLE  ;
//
ID   2.4.2.7
DE   Adenine phosphoribosyltransferase.
AN   AMP diphosphorylase.
AN   AMP pyrophosphorylase.
AN   APRT.
AN   Transphosphoribosidase.
CA   AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.
CC   -!- 5-amino-4-imidazolecarboxamide can replace adenine.
PR   PROSITE; PDOC00096;
DR   P31166, APT1_ARATH ;  A4FYD7, APT1_METM5 ;  A6VID5, APT1_METM7 ;
DR   Q6M0X3, APT1_METMP ;  A6URC7, APT1_METVS ;  Q2K5T4, APT1_RHIEC ;
DR   Q43199, APT1_WHEAT ;  P49435, APT1_YEAST ;  Q42563, APT2_ARATH ;
DR   A4G043, APT2_METM5 ;  A6VJW6, APT2_METM7 ;  Q6LZG8, APT2_METMP ;
DR   A6USF2, APT2_METVS ;  Q8KKS1, APT2_RHIEC ;  P36973, APT2_YEAST ;
DR   B0CBF7, APT_ACAM1  ;  A9NGG3, APT_ACHLI  ;  A1TWI0, APT_ACIAC  ;
DR   Q1IKJ1, APT_ACIBL  ;  A0LUK1, APT_ACIC1  ;  C1F3T2, APT_ACIC5  ;
DR   A5FVJ4, APT_ACICJ  ;  B9MIH9, APT_ACIET  ;  A1WDB0, APT_ACISJ  ;
DR   A3MYY8, APT_ACTP2  ;  B3H0A8, APT_ACTP7  ;  B0BSS1, APT_ACTPJ  ;
DR   A6VMZ1, APT_ACTSZ  ;  A0KKD3, APT_AERHH  ;  A4SMN3, APT_AERS4  ;
DR   Q8UD91, APT_AGRT5  ;  B6EJ41, APT_ALISL  ;  A6TQN8, APT_ALKMQ  ;
DR   A8MGN2, APT_ALKOO  ;  B8JDQ9, APT_ANAD2  ;  Q2INZ6, APT_ANADE  ;
DR   A7H8F4, APT_ANADF  ;  B4UE87, APT_ANASK  ;  B9ML31, APT_ANATD  ;
DR   Q3MAA1, APT_ANAVT  ;  A8ESP0, APT_ARCB4  ;  A0JV33, APT_ARTS2  ;
DR   Q756E2, APT_ASHGO  ;  A8IEI6, APT_AZOC5  ;  A7Z756, APT_BACA2  ;
DR   C3P995, APT_BACAA  ;  C3L613, APT_BACAC  ;  A0RJ16, APT_BACAH  ;
DR   Q81LI1, APT_BACAN  ;  B7JPZ4, APT_BACC0  ;  Q730C4, APT_BACC1  ;
DR   B7IIS0, APT_BACC2  ;  B7HE42, APT_BACC4  ;  B7HQG7, APT_BACC7  ;
DR   A7GT90, APT_BACCN  ;  B9IYY2, APT_BACCQ  ;  Q817X3, APT_BACCR  ;
DR   Q634D6, APT_BACCZ  ;  Q5LIY6, APT_BACFN  ;  Q650H6, APT_BACFR  ;
DR   Q9KDH2, APT_BACHD  ;  Q6HDB8, APT_BACHK  ;  Q65GQ8, APT_BACLD  ;
DR   A8FFQ0, APT_BACP2  ;  Q5WHQ1, APT_BACSK  ;  O34443, APT_BACSU  ;
DR   Q8A2N8, APT_BACTN  ;  A6KZN9, APT_BACV8  ;  A9VIN4, APT_BACWK  ;
DR   Q6MPK7, APT_BDEBA  ;  B2IBU5, APT_BEII9  ;  B8DUE5, APT_BIFA0  ;
DR   A1A1K5, APT_BIFAA  ;  B3DRY2, APT_BIFLD  ;  Q8G6B5, APT_BIFLO  ;
DR   B7GR20, APT_BIFLS  ;  Q7VRB8, APT_BLOFL  ;  Q493A5, APT_BLOPB  ;
DR   Q2KUE4, APT_BORA1  ;  Q0SM77, APT_BORAP  ;  Q7WEY7, APT_BORBR  ;
DR   O51718, APT_BORBU  ;  B7J0M3, APT_BORBZ  ;  Q65ZZ7, APT_BORGA  ;
DR   Q7W3L2, APT_BORPA  ;  A9I0U7, APT_BORPD  ;  Q7W089, APT_BORPE  ;
DR   Q56JW4, APT_BOVIN  ;  C0QVL4, APT_BRAHW  ;  Q89SB5, APT_BRAJA  ;
DR   A5EE90, APT_BRASB  ;  A4YPM4, APT_BRASO  ;  C0ZAP9, APT_BREBN  ;
DR   B2S701, APT_BRUA1  ;  Q2YM57, APT_BRUA2  ;  Q57BX7, APT_BRUAB  ;
DR   A9M6K5, APT_BRUC2  ;  P63542, APT_BRUME  ;  A5VRR9, APT_BRUO2  ;
DR   B0CHX9, APT_BRUSI  ;  P63543, APT_BRUSU  ;  B1YN34, APT_BURA4  ;
DR   Q1BTI4, APT_BURCA  ;  B1JYN1, APT_BURCC  ;  A0KAK7, APT_BURCH  ;
DR   Q0BBS3, APT_BURCM  ;  A9AF06, APT_BURM1  ;  A2S6D4, APT_BURM9  ;
DR   A1UZL8, APT_BURMS  ;  A3NRB5, APT_BURP0  ;  Q3JW68, APT_BURP1  ;
DR   A3N5L9, APT_BURP6  ;  B2JCQ7, APT_BURP8  ;  B2SXI3, APT_BURPP  ;
DR   Q63XK0, APT_BURPS  ;  Q39CV8, APT_BURS3  ;  Q2T199, APT_BURTA  ;
DR   A4JHX7, APT_BURVG  ;  Q145V4, APT_BURXL  ;  O31060, APT_BUTFI  ;
DR   P91455, APT_CAEEL  ;  A4XI79, APT_CALS8  ;  A7ZCG7, APT_CAMC1  ;
DR   A7GXJ2, APT_CAMC5  ;  A0RQ44, APT_CAMFF  ;  A7I261, APT_CAMHC  ;
DR   A8FLX6, APT_CAMJ8  ;  A7H3C4, APT_CAMJD  ;  Q9PP06, APT_CAMJE  ;
DR   A1VZR0, APT_CAMJJ  ;  Q5HUN2, APT_CAMJR  ;  Q5ALX8, APT_CANAL  ;
DR   Q3AAI8, APT_CARHZ  ;  A0RVQ8, APT_CENSY  ;  A9WCV7, APT_CHLAA  ;
DR   Q3AT37, APT_CHLCH  ;  B3EFG3, APT_CHLL2  ;  B3QQD1, APT_CHLP8  ;
DR   B3EMG7, APT_CHLPB  ;  A1BDK4, APT_CHLPD  ;  Q8KFM9, APT_CHLTE  ;
DR   Q1QVQ9, APT_CHRSD  ;  Q7NRK9, APT_CHRVO  ;  A8AJX4, APT_CITK8  ;
DR   A5CSP7, APT_CLAM3  ;  B0RGV9, APT_CLAMS  ;  Q97GU0, APT_CLOAB  ;
DR   A7FY09, APT_CLOB1  ;  A6LTN5, APT_CLOB8  ;  B2V345, APT_CLOBA  ;
DR   B2TMZ9, APT_CLOBB  ;  A5I6E1, APT_CLOBH  ;  B1IME3, APT_CLOBK  ;
DR   A7GHS8, APT_CLOBL  ;  B1L0A2, APT_CLOBM  ;  B8I3F7, APT_CLOCE  ;
DR   Q183I0, APT_CLOD6  ;  B9E5P8, APT_CLOK1  ;  A5N1Z4, APT_CLOK5  ;
DR   A0PZW4, APT_CLONN  ;  Q0TP22, APT_CLOP1  ;  Q8XJ22, APT_CLOPE  ;
DR   A9KIA0, APT_CLOPH  ;  Q0SRP2, APT_CLOPS  ;  Q892A7, APT_CLOTE  ;
DR   A3DF48, APT_CLOTH  ;  Q47XQ8, APT_COLP3  ;  B5Y8Y0, APT_COPPD  ;
DR   Q6NGY0, APT_CORDI  ;  Q8FPL0, APT_COREF  ;  A4QEM8, APT_CORGB  ;
DR   O87330, APT_CORGL  ;  Q4JVE4, APT_CORJK  ;  C4LIX2, APT_CORK4  ;
DR   P47952, APT_CRIGR  ;  Q0KEM6, APT_CUPNH  ;  Q476D8, APT_CUPPJ  ;
DR   B2AGV9, APT_CUPTR  ;  B1WQD7, APT_CYAA5  ;  B8HS80, APT_CYAP4  ;
DR   B7KKQ8, APT_CYAP7  ;  B7JVC2, APT_CYAP8  ;  Q11TJ3, APT_CYTH3  ;
DR   Q6BZF9, APT_DEBHA  ;  C6BSW0, APT_DESAD  ;  B8FQU0, APT_DESHD  ;
DR   Q24UQ1, APT_DESHY  ;  C4XU70, APT_DESMR  ;  A8ZWU1, APT_DESOH  ;
DR   A4J2G8, APT_DESRM  ;  Q55C82, APT_DICDI  ;  A5EVW7, APT_DICNV  ;
DR   A8LPV7, APT_DINSH  ;  P12426, APT_DROME  ;  P54363, APT_DROPS  ;
DR   A7ZIM8, APT_ECO24  ;  B7UKE9, APT_ECO27  ;  B7MDZ1, APT_ECO45  ;
DR   B7L794, APT_ECO55  ;  Q8XD48, APT_ECO57  ;  B5Z3X9, APT_ECO5E  ;
DR   B7NIG1, APT_ECO7I  ;  B7MQI4, APT_ECO81  ;  B7M3W1, APT_ECO8A  ;
DR   C4ZUS3, APT_ECOBW  ;  B1XFQ6, APT_ECODH  ;  A7ZXC7, APT_ECOHS  ;
DR   A1A8D5, APT_ECOK1  ;  Q0TKH2, APT_ECOL5  ;  P69504, APT_ECOL6  ;
DR   B1IZC5, APT_ECOLC  ;  P69503, APT_ECOLI  ;  B7N922, APT_ECOLU  ;
DR   B6I0C1, APT_ECOSE  ;  B1LJM6, APT_ECOSM  ;  Q1RF67, APT_ECOUT  ;
DR   C5BCZ7, APT_EDWI9  ;  A4W7F3, APT_ENT38  ;  Q834G6, APT_ENTFA  ;
DR   A7MJV7, APT_ENTS8  ;  Q6D800, APT_ERWCT  ;  B2VHU9, APT_ERWT9  ;
DR   Q2N669, APT_ERYLH  ;  B7LLQ1, APT_ESCF3  ;  C4ZF43, APT_EUBR3  ;
DR   B1YJG1, APT_EXIS2  ;  C4L531, APT_EXISA  ;  A7HLE2, APT_FERNB  ;
DR   B0S0M3, APT_FINM2  ;  A5FFL9, APT_FLAJ1  ;  Q0RNU1, APT_FRAAA  ;
DR   B0TWU0, APT_FRAP2  ;  Q2JD90, APT_FRASC  ;  A8KZE2, APT_FRASN  ;
DR   Q14JZ2, APT_FRAT1  ;  A7NEG0, APT_FRATF  ;  Q2A1J5, APT_FRATH  ;
DR   B2SEZ5, APT_FRATM  ;  A0Q8C6, APT_FRATN  ;  Q0BK98, APT_FRATO  ;
DR   Q5NII9, APT_FRATT  ;  A4IW38, APT_FRATW  ;  Q8RDM9, APT_FUSNN  ;
DR   B5EHF2, APT_GEOBB  ;  Q5KWS2, APT_GEOKA  ;  B3E683, APT_GEOLS  ;
DR   Q39VR8, APT_GEOMG  ;  B9M4Z1, APT_GEOSF  ;  Q74CZ3, APT_GEOSL  ;
DR   C6E585, APT_GEOSM  ;  C5D514, APT_GEOSW  ;  A4IRA1, APT_GEOTN  ;
DR   A5G4S5, APT_GEOUR  ;  Q64414, APT_GERCA  ;  Q7NGZ0, APT_GLOVI  ;
DR   A9HEW1, APT_GLUDA  ;  Q5FSN7, APT_GLUOX  ;  Q0BVB8, APT_GRABC  ;
DR   A0LYK2, APT_GRAFK  ;  Q7VKQ4, APT_HAEDU  ;  Q4QJV7, APT_HAEI8  ;
DR   A5UBP3, APT_HAEIE  ;  A5UF74, APT_HAEIG  ;  P43856, APT_HAEIN  ;
DR   Q0I3U5, APT_HAES1  ;  B0UWQ8, APT_HAES2  ;  Q5UX13, APT_HALMA  ;
DR   B8CXF1, APT_HALOH  ;  B0R3M8, APT_HALS3  ;  Q9HRT1, APT_HALSA  ;
DR   Q18JK6, APT_HALWD  ;  Q17W08, APT_HELAH  ;  Q7VGF2, APT_HELHP  ;
DR   B6JLF4, APT_HELP2  ;  B5Z6U3, APT_HELPG  ;  Q1CTV4, APT_HELPH  ;
DR   Q9ZLQ9, APT_HELPJ  ;  B2UTQ6, APT_HELPS  ;  O25296, APT_HELPY  ;
DR   A9AYX1, APT_HERA2  ;  P07741, APT_HUMAN  ;  Q5QWS1, APT_IDILO  ;
DR   Q28MD3, APT_JANSC  ;  A6WCH4, APT_KINRD  ;  B5Y0N8, APT_KLEP3  ;
DR   A6T5N2, APT_KLEP7  ;  Q6CWV0, APT_KLULA  ;  C5CIH1, APT_KOSOT  ;
DR   Q5FJP9, APT_LACAC  ;  Q03QP8, APT_LACBA  ;  Q038P1, APT_LACC3  ;
DR   Q1G9R7, APT_LACDA  ;  Q049X1, APT_LACDB  ;  Q044A4, APT_LACGA  ;
DR   A8YVP7, APT_LACH4  ;  Q74IU0, APT_LACJO  ;  Q9CHT5, APT_LACLA  ;
DR   A2RIW0, APT_LACLM  ;  Q031A0, APT_LACLS  ;  Q88VH0, APT_LACPL  ;
DR   Q1WT53, APT_LACS1  ;  Q38W53, APT_LACSS  ;  B0SIB4, APT_LEPBA  ;
DR   Q04NG3, APT_LEPBJ  ;  Q04WP5, APT_LEPBL  ;  Q75FP0, APT_LEPIC  ;
DR   Q8EXN2, APT_LEPIN  ;  B1MZQ2, APT_LEUCK  ;  Q03W57, APT_LEUMM  ;
DR   P0A2X6, APT_LISIN  ;  C1KVH1, APT_LISMC  ;  Q71ZE6, APT_LISMF  ;
DR   B8DHM4, APT_LISMH  ;  P0A2X5, APT_LISMO  ;  A0AIX3, APT_LISW6  ;
DR   B1HV83, APT_LYSSC  ;  B9E711, APT_MACCJ  ;  Q2W3C2, APT_MAGSA  ;
DR   Q65U83, APT_MANSM  ;  A1U4H0, APT_MARAV  ;  Q0ARQ1, APT_MARMM  ;
DR   A6VXH5, APT_MARMS  ;  Q64427, APT_MASHI  ;  Q6F1J0, APT_MESFL  ;
DR   Q11GC0, APT_MESSB  ;  A6UX50, APT_META3  ;  B7KY35, APT_METC4  ;
DR   Q60AN2, APT_METCA  ;  A9W0A8, APT_METEP  ;  Q1GYN9, APT_METFK  ;
DR   B3DXQ2, APT_METI4  ;  Q59049, APT_METJA  ;  Q8TXQ0, APT_METKA  ;
DR   B8ILP3, APT_METNO  ;  B1ZKA1, APT_METPB  ;  A2SMH6, APT_METPP  ;
DR   B1LUP7, APT_METRJ  ;  B0UKF2, APT_METS4  ;  O27375, APT_METTH  ;
DR   O33174, APT_METTM  ;  B0JR14, APT_MICAN  ;  P08030, APT_MOUSE  ;
DR   P47956, APT_MUSPA  ;  P47957, APT_MUSSI  ;  A0QIA9, APT_MYCA1  ;
DR   B1MCI5, APT_MYCA9  ;  A5IZD7, APT_MYCAP  ;  P59959, APT_MYCBO  ;
DR   A1KLT2, APT_MYCBP  ;  Q2SRZ3, APT_MYCCT  ;  Q9RFQ2, APT_MYCFE  ;
DR   Q7NBS4, APT_MYCGA  ;  P47518, APT_MYCGE  ;  A4TBR2, APT_MYCGI  ;
DR   Q601D6, APT_MYCH2  ;  Q4A8Q0, APT_MYCH7  ;  Q4AAL9, APT_MYCHJ  ;
DR   B2HN75, APT_MYCMM  ;  Q6KI92, APT_MYCMO  ;  Q6MTD4, APT_MYCMS  ;
DR   Q741P3, APT_MYCPA  ;  Q8EUA8, APT_MYCPE  ;  P75388, APT_MYCPN  ;
DR   Q98QN9, APT_MYCPU  ;  A0QWJ5, APT_MYCS2  ;  Q4A577, APT_MYCS5  ;
DR   A3PYX7, APT_MYCSJ  ;  A1UFB6, APT_MYCSK  ;  Q1B9P7, APT_MYCSS  ;
DR   A5U5T4, APT_MYCTA  ;  Q50637, APT_MYCTU  ;  A0PPE4, APT_MYCUA  ;
DR   A1T894, APT_MYCVP  ;  Q1D1H1, APT_MYXXD  ;  B2A0H0, APT_NATTJ  ;
DR   Q5F774, APT_NEIG1  ;  A9M1N3, APT_NEIM0  ;  Q9JT95, APT_NEIMA  ;
DR   Q9JYB4, APT_NEIMB  ;  A1KV71, APT_NEIMF  ;  Q0AJC5, APT_NITEC  ;
DR   Q82XS2, APT_NITEU  ;  Q1QIH5, APT_NITHX  ;  A9A3N4, APT_NITMS  ;
DR   Q2YAI3, APT_NITMU  ;  Q3JEP4, APT_NITOC  ;  A6Q2W2, APT_NITSB  ;
DR   Q3SPC5, APT_NITWN  ;  Q5YTF5, APT_NOCFA  ;  A1SJB1, APT_NOCSJ  ;
DR   B2IU50, APT_NOSP7  ;  Q8YNI3, APT_NOSS1  ;  Q2GAK1, APT_NOVAD  ;
DR   Q8EPR5, APT_OCEIH  ;  A6WZD8, APT_OCHA4  ;  Q04F01, APT_OENOB  ;
DR   A1B843, APT_PARDP  ;  A7HVC7, APT_PARL1  ;  P57841, APT_PASMU  ;
DR   C6DB82, APT_PECCP  ;  Q03F39, APT_PEDPA  ;  Q3A4N0, APT_PELCD  ;
DR   Q3B250, APT_PELLD  ;  B4SCV2, APT_PELPB  ;  A1ASM0, APT_PELPD  ;
DR   A5D3H8, APT_PELTS  ;  Q4FLB9, APT_PELUB  ;  A9BG28, APT_PETMO  ;
DR   Q7N0N9, APT_PHOLL  ;  Q6LTE9, APT_PHOPR  ;  B1XUX7, APT_POLNS  ;
DR   A4SX83, APT_POLSQ  ;  B4S410, APT_PROA2  ;  Q6A8K3, APT_PROAC  ;
DR   A3PE89, APT_PROM0  ;  A2C2A5, APT_PROM1  ;  A8G657, APT_PROM2  ;
DR   A2C9I6, APT_PROM3  ;  A9BC43, APT_PROM4  ;  A2BXB1, APT_PROM5  ;
DR   Q31AA3, APT_PROM9  ;  Q7VAL5, APT_PROMA  ;  B4EU76, APT_PROMH  ;
DR   Q7V7D8, APT_PROMM  ;  Q7V0X5, APT_PROMP  ;  A2BRV3, APT_PROMS  ;
DR   Q46KW1, APT_PROMT  ;  A4SGB1, APT_PROVI  ;  Q48GH3, APT_PSE14  ;
DR   Q15RT2, APT_PSEA6  ;  A6V7V8, APT_PSEA7  ;  B7UVH9, APT_PSEA8  ;
DR   Q02K26, APT_PSEAB  ;  Q04633, APT_PSEAE  ;  Q1ICH9, APT_PSEE4  ;
DR   Q4KFF5, APT_PSEF5  ;  C3K148, APT_PSEFS  ;  Q3IKN5, APT_PSEHT  ;
DR   A4XVK6, APT_PSEMY  ;  A5W0U8, APT_PSEP1  ;  Q3KFA3, APT_PSEPF  ;
DR   B0KPW6, APT_PSEPG  ;  Q88F33, APT_PSEPK  ;  B1JBZ0, APT_PSEPW  ;
DR   Q884U6, APT_PSESM  ;  P47202, APT_PSEST  ;  Q4ZQW4, APT_PSEU2  ;
DR   A4VKK1, APT_PSEU5  ;  A1SX04, APT_PSYIN  ;  Q1LRM9, APT_RALME  ;
DR   Q8Y2B9, APT_RALSO  ;  P36972, APT_RAT    ;  A9WQH7, APT_RENSM  ;
DR   Q9RQF8, APT_RHIGA  ;  Q1MDK6, APT_RHIL3  ;  Q98HV0, APT_RHILO  ;
DR   B5ZY62, APT_RHILW  ;  Q92N62, APT_RHIME  ;  Q7UR74, APT_RHOBA  ;
DR   B6IT90, APT_RHOCS  ;  Q21QM7, APT_RHOFD  ;  C1B4D6, APT_RHOOB  ;
DR   Q2IS06, APT_RHOP2  ;  Q6N1B4, APT_RHOPA  ;  Q20Y76, APT_RHOPB  ;
DR   Q130R0, APT_RHOPS  ;  B3QA01, APT_RHOPT  ;  Q2RWT4, APT_RHORT  ;
DR   A3PGY5, APT_RHOS1  ;  Q3J5E9, APT_RHOS4  ;  A4WQ67, APT_RHOS5  ;
DR   B9KM05, APT_RHOSK  ;  Q0S1C1, APT_RHOSR  ;  A7NG77, APT_ROSCS  ;
DR   Q167V0, APT_ROSDO  ;  A5URA4, APT_ROSS1  ;  Q1AW34, APT_RUBXD  ;
DR   A4FBB2, APT_SACEN  ;  B5EXM5, APT_SALA4  ;  A8LXX3, APT_SALAI  ;
DR   A9MLY9, APT_SALAR  ;  Q57S81, APT_SALCH  ;  B5FKY7, APT_SALDC  ;
DR   B5QU72, APT_SALEP  ;  B5R607, APT_SALG2  ;  B4T9H6, APT_SALHS  ;
DR   B4SWX6, APT_SALNS  ;  Q5PFK3, APT_SALPA  ;  A9MW92, APT_SALPB  ;
DR   C0Q807, APT_SALPC  ;  B5BD49, APT_SALPK  ;  B4TMG1, APT_SALSV  ;
DR   Q8Z8T4, APT_SALTI  ;  A4X5X7, APT_SALTO  ;  Q8ZRA2, APT_SALTY  ;
DR   O42842, APT_SCHPO  ;  A8GAU8, APT_SERP5  ;  A1S560, APT_SHEAM  ;
DR   B8E700, APT_SHEB2  ;  A3D5Q5, APT_SHEB5  ;  A6WPL2, APT_SHEB8  ;
DR   A9L5S5, APT_SHEB9  ;  Q12LL4, APT_SHEDO  ;  Q080R2, APT_SHEFN  ;
DR   B0TNZ8, APT_SHEHH  ;  A3QF54, APT_SHELP  ;  Q8EFG1, APT_SHEON  ;
DR   A8H2P5, APT_SHEPA  ;  A4Y7U1, APT_SHEPC  ;  B8CMY5, APT_SHEPW  ;
DR   A0KY07, APT_SHESA  ;  A8FX87, APT_SHESH  ;  Q0HHZ1, APT_SHESM  ;
DR   Q0HU91, APT_SHESR  ;  A1RIP7, APT_SHESW  ;  B1KNJ9, APT_SHEWM  ;
DR   B2U4S2, APT_SHIB3  ;  Q325C7, APT_SHIBS  ;  Q32J49, APT_SHIDS  ;
DR   Q0T7B5, APT_SHIF8  ;  Q83M42, APT_SHIFL  ;  Q3Z4T0, APT_SHISS  ;
DR   Q5LNY7, APT_SILPO  ;  Q1GE59, APT_SILST  ;  A6UBS2, APT_SINMW  ;
DR   Q2NV62, APT_SODGM  ;  Q01QQ9, APT_SOLUE  ;  A9GFF3, APT_SORC5  ;
DR   Q1GTG6, APT_SPHAL  ;  A7X350, APT_STAA1  ;  A6U2A3, APT_STAA2  ;
DR   Q2FG92, APT_STAA3  ;  Q2FXU0, APT_STAA8  ;  A5ITF9, APT_STAA9  ;
DR   Q2YT95, APT_STAAB  ;  Q5HFC8, APT_STAAC  ;  A6QHH7, APT_STAAE  ;
DR   P68778, APT_STAAM  ;  P68779, APT_STAAN  ;  Q6GG69, APT_STAAR  ;
DR   Q6G8T4, APT_STAAS  ;  A8Z2G2, APT_STAAT  ;  P68780, APT_STAAU  ;
DR   P68781, APT_STAAW  ;  B9DNG3, APT_STACT  ;  Q5HNR6, APT_STAEQ  ;
DR   Q8CS95, APT_STAES  ;  Q4L6Y0, APT_STAHJ  ;  Q49Y73, APT_STAS1  ;
DR   P47958, APT_STOLO  ;  Q3K0P8, APT_STRA1  ;  Q8E4W5, APT_STRA3  ;
DR   Q8DZA4, APT_STRA5  ;  Q827T5, APT_STRAW  ;  Q93AJ8, APT_STRCL  ;
DR   P52561, APT_STRCO  ;  C0MAM5, APT_STRE4  ;  B4U3L7, APT_STREM  ;
DR   Q8KLQ0, APT_STRGB  ;  A8AWY0, APT_STRGC  ;  Q8DT95, APT_STRMU  ;
DR   P63546, APT_STRP1  ;  Q04JH1, APT_STRP2  ;  P0CZ62, APT_STRP3  ;
DR   B5E6M0, APT_STRP4  ;  Q5XCH4, APT_STRP6  ;  C1C8G8, APT_STRP7  ;
DR   P63548, APT_STRP8  ;  Q1JC56, APT_STRPB  ;  Q1JM38, APT_STRPC  ;
DR   Q1JH84, APT_STRPD  ;  Q1J702, APT_STRPF  ;  A2REX9, APT_STRPG  ;
DR   B1ICZ7, APT_STRPI  ;  B8ZLT9, APT_STRPJ  ;  Q48TY5, APT_STRPM  ;
DR   P63544, APT_STRPN  ;  P0CZ63, APT_STRPQ  ;  B5XL39, APT_STRPZ  ;
DR   P63545, APT_STRR6  ;  A4W292, APT_STRS2  ;  C0MDK3, APT_STRS7  ;
DR   A3CNR3, APT_STRSV  ;  A4VVY4, APT_STRSY  ;  Q5LZD4, APT_STRT1  ;
DR   Q5M3Y6, APT_STRT2  ;  Q03K92, APT_STRTD  ;  B9DUP2, APT_STRU0  ;
DR   C1CLS6, APT_STRZP  ;  C1CSJ8, APT_STRZT  ;  Q30RI5, APT_SULDN  ;
DR   A6Q809, APT_SULNB  ;  Q67LM3, APT_SYMTH  ;  Q2JT47, APT_SYNJA  ;
DR   Q2JI33, APT_SYNJB  ;  B1XL39, APT_SYNP2  ;  Q5N1I0, APT_SYNP6  ;
DR   A5GLQ5, APT_SYNPW  ;  Q7TTW1, APT_SYNPX  ;  A5GSL0, APT_SYNR3  ;
DR   Q0IAT7, APT_SYNS3  ;  Q3AYP0, APT_SYNS9  ;  Q3AIK3, APT_SYNSC  ;
DR   P73935, APT_SYNY3  ;  B7IEY2, APT_THEAB  ;  Q8DGH9, APT_THEEB  ;
DR   Q47N45, APT_THEFY  ;  A8F7S9, APT_THELT  ;  A6LP26, APT_THEM4  ;
DR   Q9X1A4, APT_THEMA  ;  B9K8V0, APT_THENN  ;  A5IMI9, APT_THEP1  ;
DR   B0K969, APT_THEP3  ;  B0K0N0, APT_THEPX  ;  B1LBU1, APT_THESQ  ;
DR   Q8RAL9, APT_THETN  ;  Q31JG9, APT_THICR  ;  C4L8U7, APT_TOLAT  ;
DR   Q73M27, APT_TREDE  ;  O84001, APT_TREPA  ;  B2S4S6, APT_TREPS  ;
DR   Q119D0, APT_TRIEI  ;  B1AJC8, APT_UREP2  ;  Q9PQ02, APT_UREPA  ;
DR   A5F2N2, APT_VIBC3  ;  Q9KT52, APT_VIBCH  ;  C3LTV0, APT_VIBCM  ;
DR   Q5E463, APT_VIBF1  ;  A7MUE7, APT_VIBHB  ;  Q87MQ1, APT_VIBPA  ;
DR   B7VL95, APT_VIBSL  ;  Q8DB25, APT_VIBVU  ;  Q7MIV1, APT_VIBVY  ;
DR   Q7M8W8, APT_WOLSU  ;  Q8PJY6, APT_XANAC  ;  Q3BSE4, APT_XANC5  ;
DR   Q4UVM8, APT_XANC8  ;  B0RS13, APT_XANCB  ;  Q8P8F9, APT_XANCP  ;
DR   Q2P2B0, APT_XANOM  ;  B2SHR3, APT_XANOP  ;  Q5GZA0, APT_XANOR  ;
DR   Q6CA53, APT_YARLI  ;  A1JNC2, APT_YERE8  ;  A7FL92, APT_YERP3  ;
DR   Q1C4P3, APT_YERPA  ;  B2K6Z1, APT_YERPB  ;  Q8ZC94, APT_YERPE  ;
DR   A9R0Q1, APT_YERPG  ;  Q1CL33, APT_YERPN  ;  A4TPB0, APT_YERPP  ;
DR   Q66DQ2, APT_YERPS  ;  B1JHN6, APT_YERPY  ;
//
ID   2.4.2.8
DE   Hypoxanthine phosphoribosyltransferase.
AN   Guanine phosphoribosyltransferase.
AN   HGPRTase.
AN   Hypoxanthine-guanine phosphoribosyltransferase.
AN   IMP diphosphorylase.
AN   IMP pyrophosphorylase.
AN   Transphosphoribosidase.
CA   IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose
CA   1-diphosphate.
CC   -!- Guanine and 6-mercaptopurine can replace hypoxanthine.
PR   PROSITE; PDOC00096;
DR   O66821, HPRT_AQUAE ;  P37472, HPRT_BACSU ;  Q3SZ18, HPRT_BOVIN ;
DR   P57291, HPRT_BUCAI ;  Q8K9U8, HPRT_BUCAP ;  Q6WIT9, HPRT_CANFA ;
DR   Q9W719, HPRT_CHICK ;  Q27541, HPRT_CRIFA ;  P00494, HPRT_CRIGR ;
DR   Q54NJ8, HPRT_DICDI ;  P0A9M3, HPRT_ECOL6 ;  P0A9M2, HPRT_ECOLI ;
DR   Q839B2, HPRT_ENTFA ;  P45078, HPRT_HAEIN ;  P00492, HPRT_HUMAN ;
DR   Q02522, HPRT_LACLA ;  P43152, HPRT_LEIDO ;  Q6LDD9, HPRT_MACFA ;
DR   P47959, HPRT_MERUN ;  P00493, HPRT_MOUSE ;  Q64531, HPRT_MUSSP ;
DR   P96794, HPRT_MYCAV ;  P0A5T1, HPRT_MYCBO ;  P47696, HPRT_MYCGE ;
DR   O69537, HPRT_MYCLE ;  P75119, HPRT_MYCPN ;  P0A5T0, HPRT_MYCTU ;
DR   A5A6I1, HPRT_PANTR ;  Q45FY6, HPRT_PIG   ;  P27605, HPRT_RAT   ;
DR   P37171, HPRT_RHOCB ;  O33799, HPRT_SALTY ;  P09383, HPRT_SCHMA ;
DR   P0A9M4, HPRT_SHIFL ;  Q5HIG5, HPRT_STAAC ;  P65827, HPRT_STAAM ;
DR   P99085, HPRT_STAAN ;  Q6GJG1, HPRT_STAAR ;  Q6GBX8, HPRT_STAAS ;
DR   P65828, HPRT_STAAW ;  Q5HRP4, HPRT_STAEQ ;  Q8CQV4, HPRT_STAES ;
DR   Q8E7Y1, HPRT_STRA3 ;  Q8E2H3, HPRT_STRA5 ;  Q8DWM8, HPRT_STRMU ;
DR   P0DD40, HPRT_STRP3 ;  Q5XEL6, HPRT_STRP6 ;  Q7CNQ9, HPRT_STRP8 ;
DR   Q97TC4, HPRT_STRPN ;  P0DD41, HPRT_STRPQ ;  Q8DRP8, HPRT_STRR6 ;
DR   Q5M216, HPRT_STRT1 ;  Q5M6K8, HPRT_STRT2 ;  Q07010, HPRT_TRYBB ;
DR   P18134, HPRT_VIBHA ;  Q04178, HPRT_YEAST ;  Q92F56, TILS_LISIN ;
DR   Q724J4, TILS_LISMF ;  Q8YAC7, TILS_LISMO ;
//
ID   2.4.2.9
DE   Uracil phosphoribosyltransferase.
AN   UMP diphosphorylase.
AN   UMP pyrophosphorylase.
CA   UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate.
DR   P71479, PYRR1_LACPL;  P59389, PYRR2_LACPL;  A3MZB9, PYRR_ACTP2 ;
DR   B3H0R5, PYRR_ACTP7 ;  B0BTQ6, PYRR_ACTPJ ;  A6VMA6, PYRR_ACTSZ ;
DR   B2ULR4, PYRR_AKKM8 ;  A6TRX7, PYRR_ALKMQ ;  A8MH75, PYRR_ALKOO ;
DR   B9MS19, PYRR_ANATD ;  Q3M8F0, PYRR_ANAVT ;  A7Z4G7, PYRR_BACA2 ;
DR   C3P661, PYRR_BACAA ;  C3L735, PYRR_BACAC ;  A0RHR3, PYRR_BACAH ;
DR   Q81WE7, PYRR_BACAN ;  B7JJX8, PYRR_BACC0 ;  Q732H8, PYRR_BACC1 ;
DR   B7IUQ1, PYRR_BACC2 ;  C1EPQ5, PYRR_BACC3 ;  B7H6M7, PYRR_BACC4 ;
DR   B7HLM5, PYRR_BACC7 ;  P41007, PYRR_BACCL ;  A7GRL6, PYRR_BACCN ;
DR   B9IVW8, PYRR_BACCQ ;  Q819R8, PYRR_BACCR ;  Q636D5, PYRR_BACCZ ;
DR   Q9K9V4, PYRR_BACHD ;  Q6HES3, PYRR_BACHK ;  A8FD12, PYRR_BACP2 ;
DR   P39765, PYRR_BACSU ;  A9VTD1, PYRR_BACWK ;  C0ZG45, PYRR_BREBN ;
DR   A4XKS9, PYRR_CALS8 ;  A9WDU6, PYRR_CHLAA ;  B8G8T1, PYRR_CHLAD ;
DR   B9LFU4, PYRR_CHLSY ;  Q97HA0, PYRR_CLOAB ;  A6LTU0, PYRR_CLOB8 ;
DR   B2V4U3, PYRR_CLOBA ;  B2TS13, PYRR_CLOBB ;  Q182T5, PYRR_CLOD6 ;
DR   A5N7G2, PYRR_CLOK5 ;  A0Q074, PYRR_CLONN ;  Q0TPA8, PYRR_CLOP1 ;
DR   Q8XJB2, PYRR_CLOPE ;  Q0SRX5, PYRR_CLOPS ;  A3DE09, PYRR_CLOTH ;
DR   Q6NH12, PYRR_CORDI ;  Q8FT38, PYRR_COREF ;  A4QEI8, PYRR_CORGB ;
DR   P59011, PYRR_CORGL ;  B7KKJ9, PYRR_CYAP7 ;  Q3Z788, PYRR_DEHE1 ;
DR   A5FQE0, PYRR_DEHSB ;  Q3ZY75, PYRR_DEHSC ;  C1CX80, PYRR_DEIDV ;
DR   Q9RVB9, PYRR_DEIRA ;  A9A079, PYRR_DESOH ;  B2KCN3, PYRR_ELUMP ;
DR   P0DH77, PYRR_ENTFA ;  F2MMP6, PYRR_ENTFO ;  Q8RG90, PYRR_FUSNN ;
DR   B5EB48, PYRR_GEOBB ;  Q5L0U8, PYRR_GEOKA ;  Q74DP6, PYRR_GEOSL ;
DR   C6DZ53, PYRR_GEOSM ;  C5D8P5, PYRR_GEOSW ;  A4IM28, PYRR_GEOTN ;
DR   Q7VM31, PYRR_HAEDU ;  Q4QN84, PYRR_HAEI8 ;  A5UA30, PYRR_HAEIE ;
DR   A5UGX0, PYRR_HAEIG ;  P44722, PYRR_HAEIN ;  A9AVM2, PYRR_HERA2 ;
DR   Q03S48, PYRR_LACBA ;  B2GEZ3, PYRR_LACF3 ;  Q02XW4, PYRR_LACLS ;
DR   B2G552, PYRR_LACRJ ;  Q1WTX5, PYRR_LACS1 ;  Q38X29, PYRR_LACSS ;
DR   Q6AF89, PYRR_LEIXX ;  B1MZJ0, PYRR_LEUCK ;  Q03WF7, PYRR_LEUMM ;
DR   Q92AG8, PYRR_LISIN ;  C1KWD9, PYRR_LISMC ;  Q71YH6, PYRR_LISMF ;
DR   B8DDR2, PYRR_LISMH ;  Q8Y660, PYRR_LISMO ;  A0AJU5, PYRR_LISW6 ;
DR   B9EB64, PYRR_MACCJ ;  Q65UX5, PYRR_MANSM ;  B0JUG8, PYRR_MICAN ;
DR   A0QI38, PYRR_MYCA1 ;  P65942, PYRR_MYCBO ;  A1KIG8, PYRR_MYCBP ;
DR   C1AN24, PYRR_MYCBT ;  B2HNE5, PYRR_MYCMM ;  Q741H6, PYRR_MYCPA ;
DR   A5U281, PYRR_MYCTA ;  P65941, PYRR_MYCTU ;  A0PPI7, PYRR_MYCUA ;
DR   B2A2U8, PYRR_NATTJ ;  Q3JE54, PYRR_NITOC ;  B2IWH8, PYRR_NOSP7 ;
DR   Q8YV98, PYRR_NOSS1 ;  Q8CXH9, PYRR_OCEIH ;  Q9CLL7, PYRR_PASMU ;
DR   Q03FM3, PYRR_PEDPA ;  A5D172, PYRR_PELTS ;  Q48P92, PYRR_PSE14 ;
DR   A6UYL3, PYRR_PSEA7 ;  B7V3Z0, PYRR_PSEA8 ;  Q02U09, PYRR_PSEAB ;
DR   Q9X6W6, PYRR_PSEAE ;  Q1I3U3, PYRR_PSEE4 ;  Q4K4E3, PYRR_PSEF5 ;
DR   Q9F4I7, PYRR_PSEFL ;  B0KM22, PYRR_PSEPG ;  Q9Z441, PYRR_PSEPU ;
DR   B1J356, PYRR_PSEPW ;  Q87VA0, PYRR_PSESM ;  Q4ZZ69, PYRR_PSEU2 ;
DR   Q8Y1L3, PYRR_RALSO ;  A7NLW5, PYRR_ROSCS ;  A5UX79, PYRR_ROSS1 ;
DR   Q1AVY5, PYRR_RUBXD ;  A7X1E5, PYRR_STAA1 ;  A6U117, PYRR_STAA2 ;
DR   Q2FHP0, PYRR_STAA3 ;  Q2FZ77, PYRR_STAA8 ;  A5IS83, PYRR_STAA9 ;
DR   Q2YXH0, PYRR_STAAB ;  Q5HGN4, PYRR_STAAC ;  A6QG99, PYRR_STAAE ;
DR   P65943, PYRR_STAAM ;  P65944, PYRR_STAAN ;  Q6GHN7, PYRR_STAAR ;
DR   Q6GA15, PYRR_STAAS ;  A8Z3N5, PYRR_STAAT ;  P65945, PYRR_STAAW ;
DR   B9DPQ3, PYRR_STACT ;  Q5HPZ3, PYRR_STAEQ ;  Q8CPJ9, PYRR_STAES ;
DR   Q4L5Q0, PYRR_STAHJ ;  Q49WX9, PYRR_STAS1 ;  Q3K0E8, PYRR_STRA1 ;
DR   Q8E4G7, PYRR_STRA3 ;  Q8DYV9, PYRR_STRA5 ;  Q9KXR1, PYRR_STRCO ;
DR   C0M760, PYRR_STRE4 ;  B4U3B2, PYRR_STREM ;  A8AX86, PYRR_STRGC ;
DR   Q8DUP7, PYRR_STRMU ;  Q9A0D0, PYRR_STRP1 ;  Q04K45, PYRR_STRP2 ;
DR   P0DD74, PYRR_STRP3 ;  B5E515, PYRR_STRP4 ;  Q5XCS1, PYRR_STRP6 ;
DR   C1C7Q6, PYRR_STRP7 ;  P59013, PYRR_STRP8 ;  Q1JCF0, PYRR_STRPB ;
DR   Q1JMD0, PYRR_STRPC ;  Q1J796, PYRR_STRPF ;  A2RF64, PYRR_STRPG ;
DR   B1IC68, PYRR_STRPI ;  B8ZJU2, PYRR_STRPJ ;  Q48U73, PYRR_STRPM ;
DR   P65946, PYRR_STRPN ;  P0DD75, PYRR_STRPQ ;  B2IQ70, PYRR_STRPS ;
DR   B5XKV8, PYRR_STRPZ ;  P65947, PYRR_STRR6 ;  A4W0Q9, PYRR_STRS2 ;
DR   C0ME81, PYRR_STRS7 ;  A3CNI9, PYRR_STRSV ;  A4VUG6, PYRR_STRSY ;
DR   Q5M0X3, PYRR_STRT1 ;  Q03LU2, PYRR_STRTD ;  B9DU60, PYRR_STRU0 ;
DR   C1CEN2, PYRR_STRZJ ;  C1CL12, PYRR_STRZP ;  C1CR28, PYRR_STRZT ;
DR   A0LH56, PYRR_SYNFM ;  Q2JX67, PYRR_SYNJA ;  Q2JJ22, PYRR_SYNJB ;
DR   B1XP88, PYRR_SYNP2 ;  Q55758, PYRR_SYNY3 ;  P96078, PYRR_THEAQ ;
DR   Q8DGJ7, PYRR_THEEB ;  B0KA38, PYRR_THEP3 ;  B0K2F0, PYRR_THEPX ;
DR   Q72KT9, PYRR_THET2 ;  Q5SK65, PYRR_THET8 ;  Q8R9R3, PYRR_THETN ;
DR   B1GYY9, PYRR_UNCTG ;  Q9FKS0, UKL1_ARATH ;  Q9LK34, UKL2_ARATH ;
DR   Q8VYB2, UKL3_ARATH ;  O65583, UKL4_ARATH ;  Q9LTY6, UKL5_ARATH ;
DR   O13867, UPP1_SCHPO ;  Q9HE15, UPP2_SCHPO ;  Q9US43, UPP3_SCHPO ;
DR   A9NEQ2, UPP_ACHLI  ;  Q6FE58, UPP_ACIAD  ;  B7GZA8, UPP_ACIB3  ;
DR   B7I752, UPP_ACIB5  ;  B2HU54, UPP_ACIBC  ;  B0VU43, UPP_ACIBS  ;
DR   A3M2R1, UPP_ACIBT  ;  B0V8B1, UPP_ACIBY  ;  B9MJ16, UPP_ACIET  ;
DR   A1W748, UPP_ACISJ  ;  A3MZB6, UPP_ACTP2  ;  B3H0R2, UPP_ACTP7  ;
DR   B0BTQ3, UPP_ACTPJ  ;  A6VQ76, UPP_ACTSZ  ;  A0KM23, UPP_AERHH  ;
DR   Q9YEN3, UPP_AERPE  ;  A4SL29, UPP_AERS4  ;  B9J6V7, UPP_AGRRK  ;
DR   Q8UJ06, UPP_AGRT5  ;  B9JYP9, UPP_AGRVS  ;  B6EJU2, UPP_ALISL  ;
DR   A6TK51, UPP_ALKMQ  ;  A8MJX1, UPP_ALKOO  ;  B4RTC0, UPP_ALTMD  ;
DR   B7GMG3, UPP_ANOFW  ;  O67914, UPP_AQUAE  ;  Q9M336, UPP_ARATH  ;
DR   A1R2Y2, UPP_ARTAT  ;  B8HCL2, UPP_ARTCA  ;  A0JSM6, UPP_ARTS2  ;
DR   C1DEU0, UPP_AZOVD  ;  A7Z9Q8, UPP_BACA2  ;  C3P1G4, UPP_BACAA  ;
DR   C3LFI9, UPP_BACAC  ;  A0RLA2, UPP_BACAH  ;  Q81JY5, UPP_BACAN  ;
DR   B7JGP0, UPP_BACC0  ;  Q72XD8, UPP_BACC1  ;  B7IQW8, UPP_BACC2  ;
DR   C1F0N8, UPP_BACC3  ;  B7HFL2, UPP_BACC4  ;  B7HY75, UPP_BACC7  ;
DR   P70881, UPP_BACCL  ;  A7GV65, UPP_BACCN  ;  B9IRU7, UPP_BACCQ  ;
DR   Q814V3, UPP_BACCR  ;  Q630T4, UPP_BACCZ  ;  Q9K6G5, UPP_BACHD  ;
DR   Q6HAX0, UPP_BACHK  ;  Q65DW6, UPP_BACLD  ;  A8FIC0, UPP_BACP2  ;
DR   Q5WB67, UPP_BACSK  ;  P39149, UPP_BACSU  ;  A9VSB3, UPP_BACWK  ;
DR   C5BXA3, UPP_BEUC1  ;  B8DVI9, UPP_BIFA0  ;  A0ZZM2, UPP_BIFAA  ;
DR   B3DPH5, UPP_BIFLD  ;  B7GNR5, UPP_BIFLS  ;  Q7VRS9, UPP_BLOFL  ;
DR   Q492F3, UPP_BLOPB  ;  Q2KWB3, UPP_BORA1  ;  Q7WMM5, UPP_BORBR  ;
DR   Q7WB58, UPP_BORPA  ;  A9HZV9, UPP_BORPD  ;  Q7VZ79, UPP_BORPE  ;
DR   Q89E48, UPP_BRAJA  ;  C0Z818, UPP_BREBN  ;  B2SC51, UPP_BRUA1  ;
DR   Q576P9, UPP_BRUAB  ;  A9MCZ3, UPP_BRUC2  ;  C0RMK4, UPP_BRUMB  ;
DR   Q8YDE5, UPP_BRUME  ;  A5VVW9, UPP_BRUO2  ;  A9WW75, UPP_BRUSI  ;
DR   Q8FUZ2, UPP_BRUSU  ;  B1YU48, UPP_BURA4  ;  B1JW40, UPP_BURCC  ;
DR   B4E5R5, UPP_BURCJ  ;  Q0BD86, UPP_BURCM  ;  A9AJK1, UPP_BURM1  ;
DR   A3MI49, UPP_BURM7  ;  A2S4B1, UPP_BURM9  ;  Q62IJ1, UPP_BURMA  ;
DR   A1V2G4, UPP_BURMS  ;  A3NT50, UPP_BURP0  ;  Q3JUF6, UPP_BURP1  ;
DR   A3N7G1, UPP_BURP6  ;  B2JE33, UPP_BURP8  ;  B2T2A6, UPP_BURPP  ;
DR   Q63VS8, UPP_BURPS  ;  Q39EA2, UPP_BURS3  ;  Q2SZS9, UPP_BURTA  ;
DR   A4JGH4, UPP_BURVG  ;  Q142L5, UPP_BURXL  ;  A7ZFB7, UPP_CAMC1  ;
DR   A7H0F9, UPP_CAMC5  ;  A0RR59, UPP_CAMFF  ;  A8FMZ1, UPP_CAMJ8  ;
DR   Q9PN13, UPP_CAMJE  ;  A1W0S0, UPP_CAMJJ  ;  Q5HTC1, UPP_CAMJR  ;
DR   B8GYP3, UPP_CAUCN  ;  Q9A627, UPP_CAUCR  ;  B0T2R0, UPP_CAUSK  ;
DR   Q9PJJ6, UPP_CHLMU  ;  Q1QVR2, UPP_CHRSD  ;  Q7NS06, UPP_CHRVO  ;
DR   A8AD93, UPP_CITK8  ;  A5CNC6, UPP_CLAM3  ;  Q97F73, UPP_CLOAB  ;
DR   A7FQG8, UPP_CLOB1  ;  C3KYI1, UPP_CLOB6  ;  A6LQG6, UPP_CLOB8  ;
DR   B2UZI9, UPP_CLOBA  ;  B2TJY9, UPP_CLOBB  ;  A5HY41, UPP_CLOBH  ;
DR   C1FQA3, UPP_CLOBJ  ;  B1IE69, UPP_CLOBK  ;  A7G9P8, UPP_CLOBL  ;
DR   B1KSR7, UPP_CLOBM  ;  B8I567, UPP_CLOCE  ;  Q180X8, UPP_CLOD6  ;
DR   B9DX75, UPP_CLOK1  ;  A5N3J1, UPP_CLOK5  ;  A0Q306, UPP_CLONN  ;
DR   Q0TNB4, UPP_CLOP1  ;  Q8XIC4, UPP_CLOPE  ;  A9KIB0, UPP_CLOPH  ;
DR   Q0SQY5, UPP_CLOPS  ;  Q898X9, UPP_CLOTE  ;  A3DIL9, UPP_CLOTH  ;
DR   Q47W53, UPP_COLP3  ;  C3PLD0, UPP_CORA7  ;  Q6NIX4, UPP_CORDI  ;
DR   Q8FRQ5, UPP_COREF  ;  A4QC29, UPP_CORGB  ;  P58998, UPP_CORGL  ;
DR   Q4JTK4, UPP_CORJK  ;  C4LKC1, UPP_CORK4  ;  B1VF60, UPP_CORU7  ;
DR   Q9RU32, UPP_DEIRA  ;  A9BWD4, UPP_DELAS  ;  C6BSG3, UPP_DESAD  ;
DR   C0QHT9, UPP_DESAH  ;  B8IZH6, UPP_DESDA  ;  Q311Z9, UPP_DESDG  ;
DR   B8FZ68, UPP_DESHD  ;  Q24MM7, UPP_DESHY  ;  C4XJX5, UPP_DESMR  ;
DR   Q6AQH2, UPP_DESPS  ;  Q72DA4, UPP_DESVH  ;  B8DP34, UPP_DESVM  ;
DR   A1VEW8, UPP_DESVV  ;  Q55GQ6, UPP_DICDI  ;  B5YDB8, UPP_DICT6  ;
DR   B8E009, UPP_DICTD  ;  A7ZPU1, UPP_ECO24  ;  B7UGN6, UPP_ECO27  ;
DR   B7MHX9, UPP_ECO45  ;  B7LCN8, UPP_ECO55  ;  P0A8F2, UPP_ECO57  ;
DR   B5Z035, UPP_ECO5E  ;  B7NQN7, UPP_ECO7I  ;  B7MYC5, UPP_ECO81  ;
DR   B7M7K2, UPP_ECO8A  ;  C4ZX73, UPP_ECOBW  ;  B1XAX3, UPP_ECODH  ;
DR   A8A2Z0, UPP_ECOHS  ;  A1ADZ1, UPP_ECOK1  ;  Q0TEZ0, UPP_ECOL5  ;
DR   P0A8F1, UPP_ECOL6  ;  B1IWG2, UPP_ECOLC  ;  P0A8F0, UPP_ECOLI  ;
DR   B7N680, UPP_ECOLU  ;  B6I570, UPP_ECOSE  ;  B1LNE8, UPP_ECOSM  ;
DR   C5BHQ5, UPP_EDWI9  ;  A4WD70, UPP_ENT38  ;  Q831G0, UPP_ENTFA  ;
DR   Q6D7S0, UPP_ERWCT  ;  B7LKE4, UPP_ESCF3  ;  C4Z9S1, UPP_EUBR3  ;
DR   B1YEG7, UPP_EXIS2  ;  C4KYT2, UPP_EXISA  ;  A7HJR3, UPP_FERNB  ;
DR   B0S2A9, UPP_FINM2  ;  B0TYR5, UPP_FRAP2  ;  Q2A285, UPP_FRATH  ;
DR   B2SDI9, UPP_FRATM  ;  A0Q5K6, UPP_FRATN  ;  Q5NGW1, UPP_FRATT  ;
DR   A4IZ90, UPP_FRATW  ;  Q8RG35, UPP_FUSNN  ;  B5EBM3, UPP_GEOBB  ;
DR   Q5KUI3, UPP_GEOKA  ;  B3E677, UPP_GEOLS  ;  Q74EM9, UPP_GEOSL  ;
DR   C6DZH8, UPP_GEOSM  ;  C5D9M4, UPP_GEOSW  ;  Q7VM34, UPP_HAEDU  ;
DR   Q4QJV5, UPP_HAEI8  ;  A5UBP1, UPP_HAEIE  ;  A5UF76, UPP_HAEIG  ;
DR   P43857, UPP_HAEIN  ;  B8F5N2, UPP_HAEPS  ;  Q0I4P2, UPP_HAES1  ;
DR   B0UW86, UPP_HAES2  ;  Q2SN06, UPP_HAHCH  ;  B9LUM1, UPP_HALLT  ;
DR   Q5UZD3, UPP_HALMA  ;  B0R7K0, UPP_HALS3  ;  Q9HN05, UPP_HALSA  ;
DR   Q18DK8, UPP_HALWD  ;  B0TI63, UPP_HELMI  ;  A6W572, UPP_KINRD  ;
DR   B5XNQ4, UPP_KLEP3  ;  A6TCB0, UPP_KLEP7  ;  B2GFU4, UPP_KOCRD  ;
DR   Q9RGY8, UPP_LACAC  ;  Q03QY1, UPP_LACBA  ;  Q03A25, UPP_LACC3  ;
DR   B3WDL1, UPP_LACCB  ;  Q1GAX2, UPP_LACDA  ;  Q04BB0, UPP_LACDB  ;
DR   B2GAT5, UPP_LACF3  ;  Q042K8, UPP_LACGA  ;  A8YUJ4, UPP_LACH4  ;
DR   Q9CEC9, UPP_LACLA  ;  P50926, UPP_LACLM  ;  Q02WM7, UPP_LACLS  ;
DR   Q9RE01, UPP_LACPL  ;  A5VIQ0, UPP_LACRD  ;  B2G680, UPP_LACRJ  ;
DR   Q1WUD3, UPP_LACS1  ;  Q93CX7, UPP_LACSK  ;  Q38WJ8, UPP_LACSS  ;
DR   C1DC78, UPP_LARHH  ;  Q5X340, UPP_LEGPA  ;  A5IE48, UPP_LEGPC  ;
DR   Q5ZTB9, UPP_LEGPH  ;  Q5WUK0, UPP_LEGPL  ;  Q6AHB4, UPP_LEIXX  ;
DR   Q927V5, UPP_LISIN  ;  C1KYV5, UPP_LISMC  ;  Q71WP0, UPP_LISMF  ;
DR   B8DBH1, UPP_LISMH  ;  Q8Y4B3, UPP_LISMO  ;  A0ALM3, UPP_LISW6  ;
DR   B1HM47, UPP_LYSSC  ;  B9E8F4, UPP_MACCJ  ;  Q65RC3, UPP_MANSM  ;
DR   A1U241, UPP_MARAV  ;  Q6F210, UPP_MESFL  ;  A4FYB9, UPP_METM5  ;
DR   A9A7A5, UPP_METM6  ;  A6VJY4, UPP_METM7  ;  Q6LZE9, UPP_METMP  ;
DR   A2SGT8, UPP_METPP  ;  A4YCQ1, UPP_METS5  ;  O27186, UPP_METTH  ;
DR   A6USD4, UPP_METVS  ;  B3PM96, UPP_MYCA5  ;  B1MFZ1, UPP_MYCA9  ;
DR   A5IYF5, UPP_MYCAP  ;  P0A659, UPP_MYCBO  ;  A1KNZ5, UPP_MYCBP  ;
DR   Q2ST42, UPP_MYCCT  ;  Q7NBH2, UPP_MYCGA  ;  P47276, UPP_MYCGE  ;
DR   P43049, UPP_MYCHO  ;  B2HDV9, UPP_MYCMM  ;  Q6KHA6, UPP_MYCMO  ;
DR   Q6MS86, UPP_MYCMS  ;  Q73UD7, UPP_MYCPA  ;  Q8EUA1, UPP_MYCPE  ;
DR   P75081, UPP_MYCPN  ;  Q98QP6, UPP_MYCPU  ;  A5U7Y3, UPP_MYCTA  ;
DR   P0A658, UPP_MYCTU  ;  Q1DG16, UPP_MYXXD  ;  Q3ISU0, UPP_NATPD  ;
DR   B2A3H5, UPP_NATTJ  ;  Q5F9P0, UPP_NEIG1  ;  B4RK50, UPP_NEIG2  ;
DR   A9M3K6, UPP_NEIM0  ;  Q9JV58, UPP_NEIMA  ;  Q9K048, UPP_NEIMB  ;
DR   A1KT34, UPP_NEIMF  ;  Q5Z187, UPP_NOCFA  ;  A1SDD5, UPP_NOCSJ  ;
DR   Q8YVB5, UPP_NOSS1  ;  Q8EM74, UPP_OCEIH  ;  A6WYH9, UPP_OCHA4  ;
DR   Q04DP1, UPP_OENOB  ;  A1B467, UPP_PARDP  ;  Q9CPL8, UPP_PASMU  ;
DR   C6DBR1, UPP_PECCP  ;  Q03EK5, UPP_PEDPA  ;  A1AMK6, UPP_PELPD  ;
DR   Q7N3F8, UPP_PHOLL  ;  Q6LN74, UPP_PHOPR  ;  A1VN11, UPP_POLNA  ;
DR   B2RIV3, UPP_PORG3  ;  P0C939, UPP_PORGI  ;  Q6A5S3, UPP_PROAC  ;
DR   B4EY88, UPP_PROMH  ;  Q48MT3, UPP_PSE14  ;  Q15ZS0, UPP_PSEA6  ;
DR   A6VC42, UPP_PSEA7  ;  B7V0J2, UPP_PSEA8  ;  Q02G28, UPP_PSEAB  ;
DR   Q9HVE6, UPP_PSEAE  ;  Q1IEV9, UPP_PSEE4  ;  Q4K6B5, UPP_PSEF5  ;
DR   C3KAJ8, UPP_PSEFS  ;  Q3IC38, UPP_PSEHT  ;  A4XQU8, UPP_PSEMY  ;
DR   A5VYH8, UPP_PSEP1  ;  Q3K6Y9, UPP_PSEPF  ;  B0KNF7, UPP_PSEPG  ;
DR   Q88PV2, UPP_PSEPK  ;  B1JEN1, UPP_PSEPW  ;  Q888A0, UPP_PSESM  ;
DR   Q4ZXU7, UPP_PSEU2  ;  A4VPB2, UPP_PSEU5  ;  A1SVA9, UPP_PSYIN  ;
DR   Q9V0K1, UPP_PYRAB  ;  Q8ZWV9, UPP_PYRAE  ;  A4WMQ7, UPP_PYRAR  ;
DR   Q8U1G7, UPP_PYRFU  ;  A1RV13, UPP_PYRIL  ;  Q5JGQ6, UPP_PYRKO  ;
DR   B2U8Z0, UPP_RALPJ  ;  Q8XXC7, UPP_RALSO  ;  A9WLN5, UPP_RENSM  ;
DR   B3PXN0, UPP_RHIE6  ;  Q1MMV8, UPP_RHIL3  ;  Q98GV3, UPP_RHILO  ;
DR   B5ZXI2, UPP_RHILW  ;  Q92T49, UPP_RHIME  ;  C3MBH2, UPP_RHISN  ;
DR   B6IW12, UPP_RHOCS  ;  C1ARF7, UPP_RHOOB  ;  Q0SK44, UPP_RHOSR  ;
DR   A7NRA6, UPP_ROSCS  ;  A5UQV0, UPP_ROSS1  ;  A5H0J4, UPP_SACKL  ;
DR   B5F173, UPP_SALA4  ;  A9MHP1, UPP_SALAR  ;  Q57LL1, UPP_SALCH  ;
DR   B5FQJ0, UPP_SALDC  ;  B5R560, UPP_SALEP  ;  B5RCX0, UPP_SALG2  ;
DR   B4TD73, UPP_SALHS  ;  B4T0M7, UPP_SALNS  ;  Q5PNJ7, UPP_SALPA  ;
DR   A9N2Y1, UPP_SALPB  ;  C0PYQ8, UPP_SALPC  ;  B5BB06, UPP_SALPK  ;
DR   Q2S320, UPP_SALRD  ;  B4TR74, UPP_SALSV  ;  P0A2M6, UPP_SALTI  ;
DR   P0A2M5, UPP_SALTY  ;  A1S7E5, UPP_SHEAM  ;  B8EAL3, UPP_SHEB2  ;
DR   A3D3D2, UPP_SHEB5  ;  A6WM35, UPP_SHEB8  ;  A9KY39, UPP_SHEB9  ;
DR   Q12MF1, UPP_SHEDO  ;  Q084L0, UPP_SHEFN  ;  B0TPW8, UPP_SHEHH  ;
DR   A3QD33, UPP_SHELP  ;  Q8EDI9, UPP_SHEON  ;  A8H5Q9, UPP_SHEPA  ;
DR   A4Y5T9, UPP_SHEPC  ;  B8CN81, UPP_SHEPW  ;  A0KYA2, UPP_SHESA  ;
DR   A8FUD4, UPP_SHESH  ;  Q0HHL7, UPP_SHESM  ;  Q0HTW9, UPP_SHESR  ;
DR   A1RKQ4, UPP_SHESW  ;  B1KIG8, UPP_SHEWM  ;  B2TXS3, UPP_SHIB3  ;
DR   Q0T222, UPP_SHIF8  ;  P0A8F3, UPP_SHIFL  ;  A6UET4, UPP_SINMW  ;
DR   Q2NS69, UPP_SODGM  ;  A7X4V6, UPP_STAA1  ;  A6U3J7, UPP_STAA2  ;
DR   Q2FF16, UPP_STAA3  ;  Q2FWE6, UPP_STAA8  ;  A5IUQ7, UPP_STAA9  ;
DR   Q2YUJ2, UPP_STAAB  ;  Q5HE88, UPP_STAAC  ;  A6QIV6, UPP_STAAE  ;
DR   P67395, UPP_STAAM  ;  P67396, UPP_STAAN  ;  Q6GEW3, UPP_STAAR  ;
DR   Q6G7J8, UPP_STAAS  ;  A8YY79, UPP_STAAT  ;  P67397, UPP_STAAW  ;
DR   B9DMF2, UPP_STACT  ;  Q5HMB1, UPP_STAEQ  ;  Q8CRN4, UPP_STAES  ;
DR   Q4L7Z3, UPP_STAHJ  ;  Q49Z59, UPP_STAS1  ;  Q3JZU9, UPP_STRA1  ;
DR   P67398, UPP_STRA3  ;  P67399, UPP_STRA5  ;  Q82FS4, UPP_STRAW  ;
DR   Q9AK76, UPP_STRCO  ;  C0M7M9, UPP_STRE4  ;  B4U4M9, UPP_STREM  ;
DR   A8AYQ0, UPP_STRGC  ;  B1VNY5, UPP_STRGG  ;  B4SS22, UPP_STRM5  ;
DR   B2FLX2, UPP_STRMK  ;  Q8DST6, UPP_STRMU  ;  P67400, UPP_STRP1  ;
DR   P0DH34, UPP_STRP3  ;  Q5XDM5, UPP_STRP6  ;  P67402, UPP_STRP8  ;
DR   Q1JN85, UPP_STRPC  ;  Q1JID6, UPP_STRPD  ;  Q1J888, UPP_STRPF  ;
DR   A2RG73, UPP_STRPG  ;  Q48V26, UPP_STRPM  ;  Q97RQ3, UPP_STRPN  ;
DR   P0DH35, UPP_STRPQ  ;  B5XJZ7, UPP_STRPZ  ;  Q8DQI3, UPP_STRR6  ;
DR   C0MGT4, UPP_STRS7  ;  P36399, UPP_STRSL  ;  A3CPK9, UPP_STRSV  ;
DR   A4VWM9, UPP_STRSY  ;  Q5M1A9, UPP_STRT1  ;  Q5M5U5, UPP_STRT2  ;
DR   Q03M79, UPP_STRTD  ;  B9DTU7, UPP_STRU0  ;  Q4JAV0, UPP_SULAC  ;
DR   C3MZM1, UPP_SULIA  ;  C4KIV1, UPP_SULIK  ;  C3MRJ6, UPP_SULIL  ;
DR   C3MY92, UPP_SULIM  ;  C3NFT0, UPP_SULIN  ;  C3N7P3, UPP_SULIY  ;
DR   Q980Q4, UPP_SULSO  ;  Q975Z7, UPP_SULTO  ;  Q67TC9, UPP_SYMTH  ;
DR   Q31MH4, UPP_SYNE7  ;  Q5MZF4, UPP_SYNP6  ;  P72753, UPP_SYNY3  ;
DR   B7IDR9, UPP_THEAB  ;  C5A6P6, UPP_THEGJ  ;  A6LMU0, UPP_THEM4  ;
DR   Q9WZI0, UPP_THEMA  ;  B9KAQ6, UPP_THENN  ;  B6YTB2, UPP_THEON  ;
DR   A5IJ64, UPP_THEP1  ;  B0K7G1, UPP_THEP3  ;  B0K1G2, UPP_THEPX  ;
DR   C6A3U9, UPP_THESM  ;  B1L7Y5, UPP_THESQ  ;  Q72J35, UPP_THET2  ;
DR   Q5SIQ7, UPP_THET8  ;  Q8RD94, UPP_THETN  ;  P93394, UPP_TOBAC  ;
DR   C4LC66, UPP_TOLAT  ;  Q26998, UPP_TOXGO  ;  O83462, UPP_TREPA  ;
DR   B1AIA5, UPP_UREP2  ;  Q9PR28, UPP_UREPA  ;  B5ZAU8, UPP_UREU1  ;
DR   C5CLM9, UPP_VARPS  ;  A1WQN5, UPP_VEREI  ;  A5F642, UPP_VIBC3  ;
DR   Q9KPY7, UPP_VIBCH  ;  C3LPM9, UPP_VIBCM  ;  B5FGY4, UPP_VIBFM  ;
DR   Q87MH1, UPP_VIBPA  ;  Q7MIK2, UPP_VIBVY  ;  Q7M8H6, UPP_WOLSU  ;
DR   P59001, UPP_XANAC  ;  Q3BS29, UPP_XANC5  ;  Q4UVY0, UPP_XANC8  ;
DR   B0RRQ3, UPP_XANCB  ;  Q9RBJ3, UPP_XANCP  ;  Q2P2V7, UPP_XANOM  ;
DR   P18562, UPP_YEAST  ;  A1JKZ8, UPP_YERE8  ;  A7FG38, UPP_YERP3  ;
DR   Q1C5P3, UPP_YERPA  ;  B2K9J9, UPP_YERPB  ;  Q8ZCX9, UPP_YERPE  ;
DR   A9QZW6, UPP_YERPG  ;  Q1CK39, UPP_YERPN  ;  A4TMP2, UPP_YERPP  ;
DR   Q668E6, UPP_YERPS  ;  B1JSF5, UPP_YERPY  ;
//
ID   2.4.2.10
DE   Orotate phosphoribosyltransferase.
AN   OPRT.
AN   Orotidine-5'-phosphate diphosphorylase.
AN   Orotidine-5'-phosphate pyrophosphorylase.
AN   Orotidylic acid phosphorylase.
CA   Orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose
CA   1-diphosphate.
CC   -!- The enzyme from higher eukaryotes also catalyzes the reaction listed
CC       as EC 4.1.1.23.
PR   PROSITE; PDOC00096;
DR   Q98AN7, PYRE1_RHILO;  Q985B1, PYRE2_RHILO;  Q6F6Z6, PYRE_ACIAD ;
DR   B7GV69, PYRE_ACIB3 ;  B7ICE9, PYRE_ACIB5 ;  B2I1J9, PYRE_ACIBC ;
DR   A3M9Y5, PYRE_ACIBT ;  B5EQ26, PYRE_ACIF5 ;  A3MZ36, PYRE_ACTP2 ;
DR   B3H0G3, PYRE_ACTP7 ;  B0BT67, PYRE_ACTPJ ;  A6VLF2, PYRE_ACTSZ ;
DR   Q9Y9D8, PYRE_AERPE ;  A4SHC9, PYRE_AERS4 ;  B9J8H7, PYRE_AGRRK ;
DR   Q8UI98, PYRE_AGRT5 ;  B9JQW1, PYRE_AGRVS ;  B4S200, PYRE_ALTMD ;
DR   B9MS28, PYRE_ANATD ;  O67742, PYRE_AQUAE ;  O28533, PYRE_ARCFU ;
DR   C1DI51, PYRE_AZOVD ;  C3P652, PYRE_BACAA ;  C3L744, PYRE_BACAC ;
DR   Q81WF6, PYRE_BACAN ;  B7JJW9, PYRE_BACC0 ;  Q732I7, PYRE_BACC1 ;
DR   B7IUP2, PYRE_BACC2 ;  B7H6L8, PYRE_BACC4 ;  P46534, PYRE_BACCL ;
DR   A7GRK7, PYRE_BACCN ;  Q819S7, PYRE_BACCR ;  Q5LI12, PYRE_BACFN ;
DR   Q64Z17, PYRE_BACFR ;  Q9K9W3, PYRE_BACHD ;  Q6HET2, PYRE_BACHK ;
DR   Q65JU3, PYRE_BACLD ;  A8FD21, PYRE_BACP2 ;  P25972, PYRE_BACSU ;
DR   Q8A1D5, PYRE_BACTN ;  A6KYP1, PYRE_BACV8 ;  A9VTC2, PYRE_BACWK ;
DR   A1US32, PYRE_BARBK ;  Q6G463, PYRE_BARHE ;  Q6G086, PYRE_BARQU ;
DR   A9IRL8, PYRE_BART1 ;  B8DUJ6, PYRE_BIFA0 ;  A1A1G3, PYRE_BIFAA ;
DR   B3DS55, PYRE_BIFLD ;  Q8G661, PYRE_BIFLO ;  B7GRU8, PYRE_BIFLS ;
DR   Q2KU70, PYRE_BORA1 ;  Q7WEU9, PYRE_BORBR ;  Q7W3H5, PYRE_BORPA ;
DR   A9I0G7, PYRE_BORPD ;  Q7VSN4, PYRE_BORPE ;  Q89BL4, PYRE_BRAJA ;
DR   A5EST0, PYRE_BRASB ;  A4YL97, PYRE_BRASO ;  B2SAD1, PYRE_BRUA1 ;
DR   Q2YN10, PYRE_BRUA2 ;  Q57E89, PYRE_BRUAB ;  A9MA28, PYRE_BRUC2 ;
DR   C0RHZ5, PYRE_BRUMB ;  P65910, PYRE_BRUME ;  A5VPJ0, PYRE_BRUO2 ;
DR   B0CKX9, PYRE_BRUSI ;  P65911, PYRE_BRUSU ;  B8D8C3, PYRE_BUCA5 ;
DR   P57622, PYRE_BUCAI ;  B8D880, PYRE_BUCAT ;  P59575, PYRE_BUCBP ;
DR   A4XKT8, PYRE_CALS8 ;  A7ZGD3, PYRE_CAMC1 ;  A7H149, PYRE_CAMC5 ;
DR   A0RRR2, PYRE_CAMFF ;  A7HZX7, PYRE_CAMHC ;  A8FK23, PYRE_CAMJ8 ;
DR   A7H1T2, PYRE_CAMJD ;  Q9PIR1, PYRE_CAMJE ;  A1VXV5, PYRE_CAMJJ ;
DR   Q5HWM9, PYRE_CAMJR ;  B9KE25, PYRE_CAMLR ;  Q3AC07, PYRE_CARHZ ;
DR   B8H621, PYRE_CAUCN ;  Q9A810, PYRE_CAUCR ;  B0T3H5, PYRE_CAUSK ;
DR   B3PG74, PYRE_CELJU ;  A0RY85, PYRE_CENSY ;  Q824L3, PYRE_CHLCV ;
DR   Q252Z2, PYRE_CHLFF ;  B3QLE2, PYRE_CHLP8 ;  B3EPT5, PYRE_CHLPB ;
DR   A1BJI2, PYRE_CHLPD ;  Q9Z7U6, PYRE_CHLPN ;  Q1QSL0, PYRE_CHRSD ;
DR   Q7NQ92, PYRE_CHRVO ;  Q97N11, PYRE_CLOAB ;  A7FYI6, PYRE_CLOB1 ;
DR   C3KU81, PYRE_CLOB6 ;  A6LS60, PYRE_CLOB8 ;  B2UW87, PYRE_CLOBA ;
DR   B2TNF7, PYRE_CLOBB ;  A5I6W5, PYRE_CLOBH ;  C1FLB0, PYRE_CLOBJ ;
DR   B1INE1, PYRE_CLOBK ;  A7GIH6, PYRE_CLOBL ;  B1L1E1, PYRE_CLOBM ;
DR   Q18CS5, PYRE_CLOD6 ;  Q0TRB3, PYRE_CLOP1 ;  Q8XL65, PYRE_CLOPE ;
DR   A9KKR4, PYRE_CLOPH ;  Q0STN9, PYRE_CLOPS ;  Q891J4, PYRE_CLOTE ;
DR   Q1DNB0, PYRE_COCIM ;  O93849, PYRE_COCP7 ;  P35788, PYRE_COLGR ;
DR   Q48AN2, PYRE_COLP3 ;  A4QHG9, PYRE_CORGB ;  Q8NM11, PYRE_CORGL ;
DR   Q45918, PYRE_COXBU ;  P0CQ41, PYRE_CRYNB ;  P0CQ40, PYRE_CRYNJ ;
DR   Q0KF45, PYRE_CUPNH ;  Q11RP3, PYRE_CYTH3 ;  Q9RX68, PYRE_DEIRA ;
DR   B8FNN4, PYRE_DESAA ;  C6BW21, PYRE_DESAD ;  A4J563, PYRE_DESRM ;
DR   A5EY64, PYRE_DICNV ;  A8LRS7, PYRE_DINSH ;  A7ZTJ3, PYRE_ECO24 ;
DR   B7UM49, PYRE_ECO27 ;  B7MFK3, PYRE_ECO45 ;  B7L766, PYRE_ECO55 ;
DR   Q8XD99, PYRE_ECO57 ;  B5YWE0, PYRE_ECO5E ;  B7NQ04, PYRE_ECO7I ;
DR   B7N1U3, PYRE_ECO81 ;  B7M4C7, PYRE_ECO8A ;  C4ZXN4, PYRE_ECOBW ;
DR   B1X976, PYRE_ECODH ;  A8A6A4, PYRE_ECOHS ;  Q0TBG7, PYRE_ECOL5 ;
DR   P0A7E4, PYRE_ECOL6 ;  B1IYV8, PYRE_ECOLC ;  P0A7E3, PYRE_ECOLI ;
DR   B7NEU6, PYRE_ECOLU ;  B6I3L9, PYRE_ECOSE ;  B1LK79, PYRE_ECOSM ;
DR   C5B9D0, PYRE_EDWI9 ;  A4W507, PYRE_ENT38 ;  P0DH75, PYRE_ENTFA ;
DR   F2MMN7, PYRE_ENTFO ;  A7MQA9, PYRE_ENTS8 ;  B2VF77, PYRE_ERWT9 ;
DR   Q2NCF5, PYRE_ERYLH ;  B7LVK4, PYRE_ESCF3 ;  C4ZF78, PYRE_EUBR3 ;
DR   P58856, PYRE_FUSNN ;  Q7VKV3, PYRE_HAEDU ;  Q4QNR7, PYRE_HAEI8 ;
DR   A5UAL7, PYRE_HAEIE ;  A5UG90, PYRE_HAEIG ;  P43855, PYRE_HAEIN ;
DR   B8F557, PYRE_HAEPS ;  Q2S8N8, PYRE_HAHCH ;  A1WZE3, PYRE_HALHL ;
DR   Q9HNG2, PYRE_HALSA ;  Q18FD1, PYRE_HALWD ;  C4K3W9, PYRE_HAMD5 ;
DR   Q17Z49, PYRE_HELAH ;  B0TDZ8, PYRE_HELMI ;  B6JN97, PYRE_HELP2 ;
DR   B5Z8Q2, PYRE_HELPG ;  Q1CS04, PYRE_HELPH ;  Q9ZJX0, PYRE_HELPJ ;
DR   B2UV21, PYRE_HELPS ;  P56162, PYRE_HELPY ;  A4G1L0, PYRE_HERAR ;
DR   A2BJ25, PYRE_HYPBU ;  Q0C3U2, PYRE_HYPNA ;  A6SUD4, PYRE_JANMA ;
DR   Q28RK4, PYRE_JANSC ;  B5XTG0, PYRE_KLEP3 ;  A6TFN4, PYRE_KLEP7 ;
DR   O13474, PYRE_KLULA ;  Q03NE4, PYRE_LACBA ;  Q74J27, PYRE_LACJO ;
DR   Q9CGM8, PYRE_LACLA ;  A2RLC0, PYRE_LACLM ;  Q02ZC9, PYRE_LACLS ;
DR   P77889, PYRE_LACPL ;  C1D6F5, PYRE_LARHH ;  Q5X5W4, PYRE_LEGPA ;
DR   A5IBA2, PYRE_LEGPC ;  Q5ZW83, PYRE_LEGPH ;  Q5WX86, PYRE_LEGPL ;
DR   B0SCV6, PYRE_LEPBA ;  Q04R73, PYRE_LEPBJ ;  Q053K4, PYRE_LEPBL ;
DR   B0SL24, PYRE_LEPBP ;  Q92AH7, PYRE_LISIN ;  Q71YI5, PYRE_LISMF ;
DR   Q8Y668, PYRE_LISMO ;  Q65W02, PYRE_MANSM ;  A1TY28, PYRE_MARAV ;
DR   Q0APC1, PYRE_MARMM ;  A6VSX4, PYRE_MARMS ;  P58859, PYRE_METAC ;
DR   O42767, PYRE_METAN ;  B7KVD0, PYRE_METC4 ;  Q8VR31, PYRE_METCA ;
DR   A9VYY9, PYRE_METEP ;  Q2FPQ2, PYRE_METHJ ;  Q58509, PYRE_METJA ;
DR   P58860, PYRE_METKA ;  A2SQ87, PYRE_METLZ ;  Q8Q0J4, PYRE_METMA ;
DR   A3CU84, PYRE_METMJ ;  Q6LX60, PYRE_METMP ;  B8IT23, PYRE_METNO ;
DR   B1ZJQ5, PYRE_METPB ;  A2SBW1, PYRE_METPP ;  B0UN77, PYRE_METS4 ;
DR   Q2NFI3, PYRE_METST ;  O27888, PYRE_METTH ;  A0QLX9, PYRE_MYCA1 ;
DR   P0A5U1, PYRE_MYCBO ;  A1KFK3, PYRE_MYCBP ;  Q9CB28, PYRE_MYCLE ;
DR   Q8EUY4, PYRE_MYCPE ;  A5TZA9, PYRE_MYCTA ;  P0A5U0, PYRE_MYCTU ;
DR   Q3IT15, PYRE_NATPD ;  Q5FAK5, PYRE_NEIG1 ;  B4RNV9, PYRE_NEIG2 ;
DR   A9M1F6, PYRE_NEIM0 ;  P65914, PYRE_NEIMA ;  P65915, PYRE_NEIMB ;
DR   A1KS25, PYRE_NEIMF ;  Q7RVF7, PYRE_NEUCR ;  Q820K1, PYRE_NITEU ;
DR   Q2YCI8, PYRE_NITMU ;  Q3J6V6, PYRE_NITOC ;  A6Q639, PYRE_NITSB ;
DR   A1SPW6, PYRE_NOCSJ ;  Q8YM41, PYRE_NOSS1 ;  Q2G9W6, PYRE_NOVAD ;
DR   Q8ER35, PYRE_OCEIH ;  A6X294, PYRE_OCHA4 ;  A7HX43, PYRE_PARL1 ;
DR   Q9CJW4, PYRE_PASMU ;  C6DIC6, PYRE_PECCP ;  A5D197, PYRE_PELTS ;
DR   B4RCV1, PYRE_PHEZH ;  Q7MY25, PYRE_PHOLL ;  Q6LVN7, PYRE_PHOPR ;
DR   Q6L2K9, PYRE_PICTO ;  P08309, PYRE_PODAS ;  A1VIL5, PYRE_POLNA ;
DR   B1XSI4, PYRE_POLNS ;  A4T0F4, PYRE_POLSQ ;  Q7MUX4, PYRE_PORGI ;
DR   B4S5W8, PYRE_PROA2 ;  Q6A910, PYRE_PROAC ;  A2C0A9, PYRE_PROM1 ;
DR   A2CCL7, PYRE_PROM3 ;  A9BDP7, PYRE_PROM4 ;  A2BUQ6, PYRE_PROM5 ;
DR   Q7VDR1, PYRE_PROMA ;  B4F0W4, PYRE_PROMH ;  Q7V4S7, PYRE_PROMM ;
DR   A4SGU2, PYRE_PROVI ;  Q48Q10, PYRE_PSE14 ;  A6VED8, PYRE_PSEA7 ;
DR   B7V5M2, PYRE_PSEA8 ;  Q02E31, PYRE_PSEAB ;  P50587, PYRE_PSEAE ;
DR   Q1I2T8, PYRE_PSEE4 ;  Q4K3R9, PYRE_PSEF5 ;  C3K476, PYRE_PSEFS ;
DR   Q3IJI1, PYRE_PSEHT ;  A5WB07, PYRE_PSEP1 ;  Q3K4M3, PYRE_PSEPF ;
DR   B0KQ92, PYRE_PSEPG ;  Q88C92, PYRE_PSEPK ;  B1J4L6, PYRE_PSEPW ;
DR   Q88BD7, PYRE_PSESM ;  Q4ZZY3, PYRE_PSEU2 ;  A4VGS1, PYRE_PSEU5 ;
DR   P0CL79, PYRE_PYRAB ;  Q8ZTG3, PYRE_PYRAE ;  A4WLH7, PYRE_PYRAR ;
DR   P0CL78, PYRE_PYRAY ;  A3MX27, PYRE_PYRCJ ;  P58861, PYRE_PYRFU ;
DR   O58855, PYRE_PYRHO ;  A1RRV2, PYRE_PYRIL ;  Q5JHF4, PYRE_PYRKO ;
DR   Q1LS40, PYRE_RALME ;  B2UD27, PYRE_RALPJ ;  Q8Y342, PYRE_RALSO ;
DR   B3Q0A6, PYRE_RHIE6 ;  Q2KCZ1, PYRE_RHIEC ;  Q1MM09, PYRE_RHIL3 ;
DR   P42719, PYRE_RHILT ;  B5ZNS6, PYRE_RHILW ;  Q92SC6, PYRE_RHIME ;
DR   C3MF81, PYRE_RHISN ;  Q7UYX5, PYRE_RHOBA ;  Q2J1V2, PYRE_RHOP2 ;
DR   Q6N0N8, PYRE_RHOPA ;  Q20WV6, PYRE_RHOPB ;  Q13CJ6, PYRE_RHOPS ;
DR   B3QC92, PYRE_RHOPT ;  A3PH80, PYRE_RHOS1 ;  Q3J555, PYRE_RHOS4 ;
DR   A4WPB6, PYRE_RHOS5 ;  B9KMA3, PYRE_RHOSK ;  Q163V5, PYRE_ROSDO ;
DR   A1AXP4, PYRE_RUTMC ;  Q21EF2, PYRE_SACD2 ;  B5EXE6, PYRE_SALA4 ;
DR   A9MKN3, PYRE_SALAR ;  Q57IA0, PYRE_SALCH ;  B5FM65, PYRE_SALDC ;
DR   B5R5G6, PYRE_SALEP ;  B5RG81, PYRE_SALG2 ;  B4T9Y5, PYRE_SALHS ;
DR   B4SXE3, PYRE_SALNS ;  Q5PC26, PYRE_SALPA ;  A9MVN7, PYRE_SALPB ;
DR   C0Q1X4, PYRE_SALPC ;  B5BI16, PYRE_SALPK ;  B4TZY3, PYRE_SALSV ;
DR   Q8Z2H5, PYRE_SALTI ;  P08870, PYRE_SALTY ;  O94331, PYRE_SCHPO ;
DR   A8GLE9, PYRE_SERP5 ;  Q8E9L5, PYRE_SHEON ;  B2TTV6, PYRE_SHIB3 ;
DR   Q31UY4, PYRE_SHIBS ;  Q329L4, PYRE_SHIDS ;  Q0SYG9, PYRE_SHIF8 ;
DR   Q83J15, PYRE_SHIFL ;  Q3YW04, PYRE_SHISS ;  Q5LQ42, PYRE_SILPO ;
DR   Q1GFQ6, PYRE_SILST ;  A6U5N7, PYRE_SINMW ;  A9GUD3, PYRE_SORC5 ;
DR   P18904, PYRE_SORMA ;  Q1GTA2, PYRE_SPHAL ;  A5VD53, PYRE_SPHWW ;
DR   Q5HGM7, PYRE_STAAC ;  P65916, PYRE_STAAM ;  P99144, PYRE_STAAN ;
DR   Q6GHN0, PYRE_STAAR ;  Q6GA08, PYRE_STAAS ;  Q8NX25, PYRE_STAAW ;
DR   Q5HPY6, PYRE_STAEQ ;  Q8CSW7, PYRE_STAES ;  Q4L5Q7, PYRE_STAHJ ;
DR   A3DM49, PYRE_STAMF ;  Q49WY6, PYRE_STAS1 ;  Q3K146, PYRE_STRA1 ;
DR   P65917, PYRE_STRA3 ;  P65918, PYRE_STRA5 ;  Q82EU1, PYRE_STRAW ;
DR   Q9X8R7, PYRE_STRCO ;  A8AXM7, PYRE_STRGC ;  B4STF6, PYRE_STRM5 ;
DR   B2FJX2, PYRE_STRMK ;  Q8DTV2, PYRE_STRMU ;  Q9A076, PYRE_STRP1 ;
DR   Q04LJ2, PYRE_STRP2 ;  P0DD68, PYRE_STRP3 ;  B5E302, PYRE_STRP4 ;
DR   Q5XCK7, PYRE_STRP6 ;  P65920, PYRE_STRP8 ;  Q1JC80, PYRE_STRPB ;
DR   Q1JM64, PYRE_STRPC ;  Q1JHA9, PYRE_STRPD ;  Q1J728, PYRE_STRPF ;
DR   A2RF04, PYRE_STRPG ;  Q48U09, PYRE_STRPM ;  P0CB78, PYRE_STRPN ;
DR   P0DD69, PYRE_STRPQ ;  Q8DQL5, PYRE_STRR6 ;  A3CN88, PYRE_STRSV ;
DR   Q5LZW8, PYRE_STRT1 ;  Q5M4H9, PYRE_STRT2 ;  Q03KS5, PYRE_STRTD ;
DR   O08359, PYRE_SULAC ;  Q30NT9, PYRE_SULDN ;  A6Q687, PYRE_SULNB ;
DR   Q9UX09, PYRE_SULSO ;  Q970X1, PYRE_SULTO ;  Q3B095, PYRE_SYNS9 ;
DR   Q3AN25, PYRE_SYNSC ;  Q55574, PYRE_SYNY3 ;  C5BLH1, PYRE_TERTT ;
DR   Q9HM15, PYRE_THEAC ;  Q8DHW5, PYRE_THEEB ;  C5A1Y3, PYRE_THEGJ ;
DR   A6LJP2, PYRE_THEM4 ;  Q9WYG6, PYRE_THEMA ;  B9KBW7, PYRE_THENN ;
DR   A5IK86, PYRE_THEP1 ;  B0KA31, PYRE_THEP3 ;  B0K2E4, PYRE_THEPX ;
DR   B1L9F7, PYRE_THESQ ;  P61498, PYRE_THET2 ;  Q5SHI8, PYRE_THET8 ;
DR   P61499, PYRE_THETH ;  P58858, PYRE_THETN ;  Q97CT9, PYRE_THEVO ;
DR   Q3SM42, PYRE_THIDA ;  B8GTF1, PYRE_THISH ;  P21846, PYRE_TRIRE ;
DR   Q83H88, PYRE_TROW8 ;  Q83FI4, PYRE_TROWT ;  Q0W6Q2, PYRE_UNCMA ;
DR   A5CVN5, PYRE_VESOH ;  Q9KVD5, PYRE_VIBCH ;  B5FFE3, PYRE_VIBFM ;
DR   Q87T92, PYRE_VIBPA ;  B7VHJ8, PYRE_VIBSL ;  Q8DDX5, PYRE_VIBVU ;
DR   Q7MPT2, PYRE_VIBVY ;  Q7MAD7, PYRE_WOLSU ;  Q8PFS5, PYRE_XANAC ;
DR   Q3BNB6, PYRE_XANC5 ;  Q4UPQ3, PYRE_XANC8 ;  B0RXL2, PYRE_XANCB ;
DR   Q8P469, PYRE_XANCP ;  Q2P898, PYRE_XANOM ;  B2I6N0, PYRE_XYLF2 ;
DR   Q9PGZ3, PYRE_XYLFA ;  B0U1J0, PYRE_XYLFM ;  Q87F16, PYRE_XYLFT ;
DR   P41923, PYRE_YARLI ;  P13298, PYRE_YEAST ;  A1JHW8, PYRE_YERE8 ;
DR   A7FCT0, PYRE_YERP3 ;  Q1C263, PYRE_YERPA ;  B2JYM9, PYRE_YERPB ;
DR   Q8ZJP7, PYRE_YERPE ;  A9R670, PYRE_YERPG ;  Q1CCZ8, PYRE_YERPN ;
DR   A4TSE1, PYRE_YERPP ;  Q66GE0, PYRE_YERPS ;  B1JQX7, PYRE_YERPY ;
DR   Q8YSY4, PYRFE_NOSS1;  P30402, PYRX_YEAST ;  Q42586, UMPS_ARATH ;
DR   P31754, UMPS_BOVIN ;  P09556, UMPS_DICDI ;  Q01637, UMPS_DROME ;
DR   P11172, UMPS_HUMAN ;  P13439, UMPS_MOUSE ;  Q25566, UMPS_NAEGR ;
DR   Q5R514, UMPS_PONAB ;  Q42942, UMPS_TOBAC ;
//
ID   2.4.2.11
DE   Nicotinate phosphoribosyltransferase.
AN   Niacin ribonucleotidase.
AN   Nicotinic acid mononucleotide glycohydrolase.
AN   Nicotinic acid mononucleotide pyrophosphorylase.
AN   Nicotinic acid phosphoribosyltransferase.
CA   Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-
CA   D-ribose 1-diphosphate.
DR   Q9UTK3, NPT1_SCHPO ;  P39683, NPT1_YEAST ;  Q10641, PNCB1_MYCTU;
DR   Q9HUP4, PNCB1_PSEAE;  O53770, PNCB2_MYCTU;  Q9HW26, PNCB2_PSEAE;
DR   Q6F6W1, PNCB_ACIAD ;  B2I1P1, PNCB_ACIBC ;  A3MA25, PNCB_ACIBT ;
DR   B9MHC7, PNCB_ACIET ;  A1W8S8, PNCB_ACISJ ;  B9J6S5, PNCB_AGRRK ;
DR   Q8UIS9, PNCB_AGRT5 ;  B9JYR4, PNCB_AGRVS ;  O32090, PNCB_BACSU ;
DR   A1UUA2, PNCB_BARBK ;  Q6G5H6, PNCB_BARHE ;  Q6G0X7, PNCB_BARQU ;
DR   A9ILN1, PNCB_BART1 ;  Q7WCZ8, PNCB_BORBR ;  Q7W5G3, PNCB_BORPA ;
DR   A9IIC5, PNCB_BORPD ;  Q7VTF7, PNCB_BORPE ;  A5PK51, PNCB_BOVIN ;
DR   Q89SS3, PNCB_BRAJA ;  A5E8V7, PNCB_BRASB ;  A4YK54, PNCB_BRASO ;
DR   B2S8A9, PNCB_BRUA1 ;  Q2YNV6, PNCB_BRUA2 ;  Q57FQ9, PNCB_BRUAB ;
DR   A9M757, PNCB_BRUC2 ;  C0RGH3, PNCB_BRUMB ;  Q8YEP2, PNCB_BRUME ;
DR   B0CIM5, PNCB_BRUSI ;  Q8G340, PNCB_BRUSU ;  B8D9E6, PNCB_BUCA5 ;
DR   P57442, PNCB_BUCAI ;  Q8K9I6, PNCB_BUCAP ;  B8D7P8, PNCB_BUCAT ;
DR   B1YVJ0, PNCB_BURA4 ;  Q1BXX4, PNCB_BURCA ;  B1JY80, PNCB_BURCC ;
DR   A0K5S6, PNCB_BURCH ;  Q0BH38, PNCB_BURCM ;  Q62LW1, PNCB_BURMA ;
DR   Q63S63, PNCB_BURPS ;  A4JCM8, PNCB_BURVG ;  Q95XX1, PNCB_CAEEL ;
DR   Q1QZ10, PNCB_CHRSD ;  Q7NSK2, PNCB_CHRVO ;  A8AIE5, PNCB_CITK8 ;
DR   Q0K8J9, PNCB_CUPNH ;  Q6P3H4, PNCB_DANRE ;  C0QFM5, PNCB_DESAH ;
DR   Q55G10, PNCB_DICDI ;  Q9VQX4, PNCB_DROME ;  A7ZK22, PNCB_ECO24 ;
DR   B7UN17, PNCB_ECO27 ;  B7MHP0, PNCB_ECO45 ;  B7LE31, PNCB_ECO55 ;
DR   Q8XDE8, PNCB_ECO57 ;  B5YT65, PNCB_ECO5E ;  B7NM43, PNCB_ECO7I ;
DR   B7MS49, PNCB_ECO81 ;  B7M860, PNCB_ECO8A ;  C4ZQ57, PNCB_ECOBW ;
DR   B1X8N5, PNCB_ECODH ;  A7ZYN4, PNCB_ECOHS ;  Q8FJ98, PNCB_ECOL6 ;
DR   P18133, PNCB_ECOLI ;  B7N398, PNCB_ECOLU ;  B6I904, PNCB_ECOSE ;
DR   B1LJT2, PNCB_ECOSM ;  C5BD56, PNCB_EDWI9 ;  A4W8V0, PNCB_ENT38 ;
DR   A7MEW8, PNCB_ENTS8 ;  Q6D454, PNCB_ERWCT ;  B2VC92, PNCB_ERWT9 ;
DR   B7LNU8, PNCB_ESCF3 ;  A4G168, PNCB_HERAR ;  Q6XQN6, PNCB_HUMAN ;
DR   Q11HJ2, PNCB_MESSB ;  Q8TMW6, PNCB_METAC ;  Q12Z05, PNCB_METBU ;
DR   Q8PSJ3, PNCB_METMA ;  Q8CC86, PNCB_MOUSE ;  Q5F836, PNCB_NEIG1 ;
DR   B4RL23, PNCB_NEIG2 ;  A9M0T9, PNCB_NEIM0 ;  Q9JTM8, PNCB_NEIMA ;
DR   Q9JYM9, PNCB_NEIMB ;  Q1QI14, PNCB_NITHX ;  A6WV52, PNCB_OCHA4 ;
DR   C6DFB8, PNCB_PECCP ;  Q7N621, PNCB_PHOLL ;  Q6LRA6, PNCB_PHOPR ;
DR   Q128P8, PNCB_POLSJ ;  B4EVC0, PNCB_PROMH ;  Q48NY1, PNCB_PSE14 ;
DR   A4XS60, PNCB_PSEMY ;  A5W9Q6, PNCB_PSEP1 ;  Q3KIW4, PNCB_PSEPF ;
DR   B0KKX3, PNCB_PSEPG ;  Q88DF7, PNCB_PSEPK ;  Q87VL5, PNCB_PSESM ;
DR   Q4ZYV7, PNCB_PSEU2 ;  A1SVJ9, PNCB_PSYIN ;  B2U8V2, PNCB_RALPJ ;
DR   Q8Y0L2, PNCB_RALSO ;  Q6XQN1, PNCB_RAT   ;  B3PXL5, PNCB_RHIE6 ;
DR   Q2KDT0, PNCB_RHIEC ;  Q98D24, PNCB_RHILO ;  B5ZWU4, PNCB_RHILW ;
DR   Q92S49, PNCB_RHIME ;  C3MFW1, PNCB_RHISN ;  B5F1U0, PNCB_SALA4 ;
DR   A9MHU8, PNCB_SALAR ;  Q57QZ3, PNCB_SALCH ;  B5FQ81, PNCB_SALDC ;
DR   B5QZD8, PNCB_SALEP ;  B5R8M1, PNCB_SALG2 ;  B4TDS5, PNCB_SALHS ;
DR   B4T172, PNCB_SALNS ;  Q5PGD8, PNCB_SALPA ;  A9N6Y6, PNCB_SALPB ;
DR   C0PXX2, PNCB_SALPC ;  B5BBM4, PNCB_SALPK ;  B4TRW6, PNCB_SALSV ;
DR   Q8Z7Y9, PNCB_SALTI ;  P22253, PNCB_SALTY ;  A8GCJ6, PNCB_SERP5 ;
DR   B2TUE4, PNCB_SHIB3 ;  Q31YR6, PNCB_SHIBS ;  Q32E52, PNCB_SHIDS ;
DR   Q83LN3, PNCB_SHIFL ;  Q3Z3I9, PNCB_SHISS ;  A6U5X9, PNCB_SINMW ;
DR   Q2NU84, PNCB_SODGM ;  Q9HJ28, PNCB_THEAC ;  A1WJL0, PNCB_VEREI ;
DR   A5F1F1, PNCB_VIBC3 ;  Q9KN67, PNCB_VIBCH ;  C3LUC2, PNCB_VIBCM ;
DR   A7N4I5, PNCB_VIBHB ;  Q87JE4, PNCB_VIBPA ;  Q8DA38, PNCB_VIBVU ;
DR   Q7MK41, PNCB_VIBVY ;  Q8PGU5, PNCB_XANAC ;  Q3BPD5, PNCB_XANC5 ;
DR   Q4UQS8, PNCB_XANC8 ;  B0RVE9, PNCB_XANCB ;  Q8PCP3, PNCB_XANCP ;
DR   Q9PED1, PNCB_XYLFA ;  Q87EC4, PNCB_XYLFT ;  A1JMP2, PNCB_YERE8 ;
DR   A7FJU4, PNCB_YERP3 ;  Q8ZG93, PNCB_YERPE ;  Q66CG6, PNCB_YERPS ;
//
ID   2.4.2.12
DE   Nicotinamide phosphoribosyltransferase.
AN   NMN diphosphorylase.
AN   NMN pyrophosphorylase.
CA   Nicotinamide D-ribonucleotide + diphosphate = nicotinamide + 5-phospho-
CA   alpha-D-ribose 1-diphosphate.
DR   P43490, NAMPT_HUMAN;  Q99KQ4, NAMPT_MOUSE;  Q52I78, NAMPT_PIG  ;
DR   Q80Z29, NAMPT_RAT  ;
//
ID   2.4.2.13
DE   Transferred entry: 2.5.1.6.
//
ID   2.4.2.14
DE   Amidophosphoribosyltransferase.
AN   Glutamine phosphoribosylpyrophosphate amidotransferase.
AN   Phosphoribosyldiphosphate 5-amidotransferase.
CA   5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = L-glutamine +
CA   5-phospho-alpha-D-ribose 1-diphosphate + H(2)O.
PR   PROSITE; PDOC00096;
PR   PROSITE; PDOC00406;
DR   O29388, PUR1_ARCFU ;  P00497, PUR1_BACSU ;  P28173, PUR1_CHICK ;
DR   Q86A85, PUR1_DICDI ;  Q27601, PUR1_DROME ;  P0AG16, PUR1_ECOLI ;
DR   P43854, PUR1_HAEIN ;  Q06203, PUR1_HUMAN ;  P35853, PUR1_LACCA ;
DR   Q57657, PUR1_METJA ;  O26742, PUR1_METTH ;  P65830, PUR1_MYCBO ;
DR   Q50028, PUR1_MYCLE ;  P65829, PUR1_MYCTU ;  Q9L6B8, PUR1_PASMU ;
DR   Q51342, PUR1_PSEAE ;  Q9V253, PUR1_PYRAB ;  O57979, PUR1_PYRHO ;
DR   P35433, PUR1_RAT   ;  P77935, PUR1_RHIEC ;  Q12698, PUR1_SACKL ;
DR   P41390, PUR1_SCHPO ;  P0AG17, PUR1_SHIFL ;  P52418, PUR1_SOYBN ;
DR   Q5HH14, PUR1_STAAC ;  P65831, PUR1_STAAM ;  P99164, PUR1_STAAN ;
DR   Q6GI14, PUR1_STAAR ;  Q6GAE3, PUR1_STAAS ;  Q8NX91, PUR1_STAAW ;
DR   Q5HQA0, PUR1_STAEQ ;  Q8CT30, PUR1_STAES ;  Q55038, PUR1_SYNE7 ;
DR   Q55621, PUR1_SYNY3 ;  P52419, PUR1_VIGAC ;  P04046, PUR1_YEAST ;
//
ID   2.4.2.15
DE   Guanosine phosphorylase.
CA   Guanosine + phosphate = guanine + alpha-D-ribose 1-phosphate.
CC   -!- Also acts on deoxyguanosine.
//
ID   2.4.2.16
DE   Urate-ribonucleotide phosphorylase.
CA   Urate D-ribonucleotide + phosphate = urate + alpha-D-ribose 1-phosphate.
//
ID   2.4.2.17
DE   ATP phosphoribosyltransferase.
AN   Phosphoribosyl-ATP diphosphorylase.
AN   Phosphoribosyl-ATP pyrophosphorylase.
CA   1-(5-phospho-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-
CA   ribose 1-diphosphate.
PR   PROSITE; PDOC01020;
DR   P60804, HIS11_GEOSL;  P60836, HIS12_GEOSL;  B0C9G3, HIS1_ACAM1 ;
DR   A1TKY3, HIS1_ACIAC ;  Q6FEC9, HIS1_ACIAD ;  Q1IKB7, HIS1_ACIBL ;
DR   B9MDV1, HIS1_ACIET ;  B7JA13, HIS1_ACIF2 ;  B5EQE6, HIS1_ACIF5 ;
DR   A1W428, HIS1_ACISJ ;  A3N3V7, HIS1_ACTP2 ;  B3GZG5, HIS1_ACTP7 ;
DR   B0BU47, HIS1_ACTPJ ;  A0KKB9, HIS1_AERHH ;  A4SMP5, HIS1_AERS4 ;
DR   Q8UHK1, HIS1_AGRT5 ;  Q0VS39, HIS1_ALCBS ;  Q0A6H9, HIS1_ALHEH ;
DR   B6EJ87, HIS1_ALISL ;  A6TKT0, HIS1_ALKMQ ;  B8JAT9, HIS1_ANAD2 ;
DR   Q2IMV6, HIS1_ANADE ;  A7HI48, HIS1_ANADF ;  B4UAY5, HIS1_ANASK ;
DR   B9MJR9, HIS1_ANATD ;  Q3M4Z2, HIS1_ANAVT ;  B7GL41, HIS1_ANOFW ;
DR   O67543, HIS1_AQUAE ;  O29665, HIS1_ARCFU ;  Q5P789, HIS1_AROAE ;
DR   A1R5S0, HIS1_ARTAT ;  B8H6U1, HIS1_ARTCA ;  A0JVK4, HIS1_ARTS2 ;
DR   Q75AK8, HIS1_ASHGO ;  B6YQ21, HIS1_AZOPC ;  A1K3M9, HIS1_AZOSB ;
DR   C1DQ66, HIS1_AZOVD ;  A7Z967, HIS1_BACA2 ;  C3P501, HIS1_BACAA ;
DR   C3L9Q2, HIS1_BACAC ;  Q81T63, HIS1_BACAN ;  B7JFZ0, HIS1_BACC0 ;
DR   P62366, HIS1_BACC1 ;  B7IN98, HIS1_BACC2 ;  C1EMQ2, HIS1_BACC3 ;
DR   B7HHG0, HIS1_BACC4 ;  B7HKC9, HIS1_BACC7 ;  A7GMU5, HIS1_BACCN ;
DR   B9IUZ5, HIS1_BACCQ ;  Q81G07, HIS1_BACCR ;  Q63DX3, HIS1_BACCZ ;
DR   Q5LAZ7, HIS1_BACFN ;  Q64RE6, HIS1_BACFR ;  Q9K6Z1, HIS1_BACHD ;
DR   Q6HLE8, HIS1_BACHK ;  Q65EF8, HIS1_BACLD ;  A8FHR4, HIS1_BACP2 ;
DR   Q5WDH7, HIS1_BACSK ;  O34520, HIS1_BACSU ;  Q8ABB0, HIS1_BACTN ;
DR   A6L2V6, HIS1_BACV8 ;  A9VLH2, HIS1_BACWK ;  Q1LT66, HIS1_BAUCH ;
DR   B8DUC3, HIS1_BIFA0 ;  A1A1J3, HIS1_BIFAA ;  B3DS05, HIS1_BIFLD ;
DR   Q8G695, HIS1_BIFLO ;  B7GRM4, HIS1_BIFLS ;  Q7VQX1, HIS1_BLOFL ;
DR   Q492K4, HIS1_BLOPB ;  Q2KTT7, HIS1_BORA1 ;  Q7WDY5, HIS1_BORBR ;
DR   Q7W2Y5, HIS1_BORPA ;  Q7VSZ2, HIS1_BORPE ;  C0QWY0, HIS1_BRAHW ;
DR   Q89DB4, HIS1_BRAJA ;  A5ECJ5, HIS1_BRASB ;  A4Z0T3, HIS1_BRASO ;
DR   B2SCY9, HIS1_BRUA1 ;  Q2YIJ9, HIS1_BRUA2 ;  Q579Q6, HIS1_BRUAB ;
DR   A9MDU6, HIS1_BRUC2 ;  C0RKC9, HIS1_BRUMB ;  Q8YB47, HIS1_BRUME ;
DR   A5VTT6, HIS1_BRUO2 ;  A9WXP5, HIS1_BRUSI ;  Q8FX92, HIS1_BRUSU ;
DR   B8D8Q1, HIS1_BUCA5 ;  P57200, HIS1_BUCAI ;  Q9ZHE7, HIS1_BUCAP ;
DR   B8D705, HIS1_BUCAT ;  P59453, HIS1_BUCBP ;  Q9RQ89, HIS1_BUCDN ;
DR   Q9RQ83, HIS1_BUCMH ;  Q9RQ86, HIS1_BUCSC ;  B1YRV4, HIS1_BURA4 ;
DR   Q1BS24, HIS1_BURCA ;  B1JU98, HIS1_BURCC ;  A0K3V1, HIS1_BURCH ;
DR   B4E634, HIS1_BURCJ ;  Q0BIX1, HIS1_BURCM ;  Q845V4, HIS1_BURM1 ;
DR   A3MPV1, HIS1_BURM7 ;  A2S747, HIS1_BURM9 ;  Q62GD8, HIS1_BURMA ;
DR   A1V8G8, HIS1_BURMS ;  A3P034, HIS1_BURP0 ;  Q3JMZ5, HIS1_BURP1 ;
DR   A3NEA0, HIS1_BURP6 ;  Q63Q85, HIS1_BURPS ;  Q39K92, HIS1_BURS3 ;
DR   Q2SUA1, HIS1_BURTA ;  A4JAW2, HIS1_BURVG ;  A4XL26, HIS1_CALS8 ;
DR   A7ZF95, HIS1_CAMC1 ;  A7GX39, HIS1_CAMC5 ;  A0RQ26, HIS1_CAMFF ;
DR   A8FNQ9, HIS1_CAMJ8 ;  A7H5U7, HIS1_CAMJD ;  Q9PM78, HIS1_CAMJE ;
DR   A1W1J9, HIS1_CAMJJ ;  Q5HSJ4, HIS1_CAMJR ;  B9KEH8, HIS1_CAMLR ;
DR   P46586, HIS1_CANAL ;  Q6FLT7, HIS1_CANGA ;  Q3AD54, HIS1_CARHZ ;
DR   B8H5P6, HIS1_CAUCN ;  Q9A2P5, HIS1_CAUCR ;  Q3AU36, HIS1_CHLCH ;
DR   B3QR09, HIS1_CHLP8 ;  A1BIW8, HIS1_CHLPD ;  Q8KB10, HIS1_CHLTE ;
DR   Q1QVE4, HIS1_CHRSD ;  Q7P0F7, HIS1_CHRVO ;  Q97KI3, HIS1_CLOAB ;
DR   A7FU76, HIS1_CLOB1 ;  C3KVX0, HIS1_CLOB6 ;  C1FN36, HIS1_CLOBJ ;
DR   B1ILA4, HIS1_CLOBK ;  A7GDQ1, HIS1_CLOBL ;  B8I5U9, HIS1_CLOCE ;
DR   Q18C67, HIS1_CLOD6 ;  B9E166, HIS1_CLOK1 ;  A5N7Q5, HIS1_CLOK5 ;
DR   A0PXP3, HIS1_CLONN ;  A9KNX6, HIS1_CLOPH ;  A3DJF0, HIS1_CLOTH ;
DR   C3PG93, HIS1_CORA7 ;  P60803, HIS1_CORDI ;  Q8FTD5, HIS1_COREF ;
DR   A4QE90, HIS1_CORGB ;  Q9Z472, HIS1_CORGL ;  Q4JVP1, HIS1_CORJK ;
DR   C4LIL5, HIS1_CORK4 ;  Q0K686, HIS1_CUPNH ;  Q46WL1, HIS1_CUPPJ ;
DR   B3R7A1, HIS1_CUPTR ;  B1WSL8, HIS1_CYAA5 ;  B8HQZ8, HIS1_CYAP4 ;
DR   B7KGT7, HIS1_CYAP7 ;  B7JZB1, HIS1_CYAP8 ;  Q11TY6, HIS1_CYTH3 ;
DR   Q6BRU4, HIS1_DEBHA ;  Q47AL4, HIS1_DECAR ;  C1CVJ5, HIS1_DEIDV ;
DR   Q1J0A0, HIS1_DEIGD ;  Q9RUE2, HIS1_DEIRA ;  B8FLE8, HIS1_DESAA ;
DR   B1I190, HIS1_DESAP ;  B8FP18, HIS1_DESHD ;  Q24QI9, HIS1_DESHY ;
DR   C4XTP0, HIS1_DESMR ;  A8ZXG7, HIS1_DESOH ;  P62364, HIS1_DESVH ;
DR   B8DQ42, HIS1_DESVM ;  A1VHE4, HIS1_DESVV ;  B5YE84, HIS1_DICT6 ;
DR   B8E2C2, HIS1_DICTD ;  A7ZNJ1, HIS1_ECO24 ;  B7UT56, HIS1_ECO27 ;
DR   B7MDH3, HIS1_ECO45 ;  B7L9P6, HIS1_ECO55 ;  Q8X8T4, HIS1_ECO57 ;
DR   B5YU75, HIS1_ECO5E ;  B7NQH1, HIS1_ECO7I ;  B7MWT8, HIS1_ECO81 ;
DR   B7M3Z8, HIS1_ECO8A ;  C4ZSA8, HIS1_ECOBW ;  B1X6V6, HIS1_ECODH ;
DR   A8A1P3, HIS1_ECOHS ;  A1ACN1, HIS1_ECOK1 ;  Q0TG68, HIS1_ECOL5 ;
DR   P60758, HIS1_ECOL6 ;  B1IZ55, HIS1_ECOLC ;  P60757, HIS1_ECOLI ;
DR   B7NC59, HIS1_ECOLU ;  B6I846, HIS1_ECOSE ;  B1LP22, HIS1_ECOSM ;
DR   Q1RA54, HIS1_ECOUT ;  C5BG10, HIS1_EDWI9 ;  A4WC68, HIS1_ENT38 ;
DR   Q6D412, HIS1_ERWCT ;  B2VFL7, HIS1_ERWT9 ;  B7LUF0, HIS1_ESCF3 ;
DR   C4Z0B1, HIS1_EUBE2 ;  C1A4M2, HIS1_GEMAT ;  B5EDS0, HIS1_GEOBB ;
DR   Q5KVC5, HIS1_GEOKA ;  B3E6L6, HIS1_GEOLS ;  Q39YP8, HIS1_GEOMG ;
DR   B9M8U7, HIS1_GEOSF ;  C6E7G0, HIS1_GEOSM ;  C5D7P3, HIS1_GEOSW ;
DR   A4ISR7, HIS1_GEOTN ;  A5G6I5, HIS1_GEOUR ;  Q7NFZ1, HIS1_GLOVI ;
DR   Q5FS84, HIS1_GLUOX ;  Q4QN75, HIS1_HAEI8 ;  A5UA21, HIS1_HAEIE ;
DR   A5UGY0, HIS1_HAEIG ;  P43853, HIS1_HAEIN ;  Q2SBJ5, HIS1_HAHCH ;
DR   A1WYW5, HIS1_HALHL ;  B9LU14, HIS1_HALLT ;  Q5UYR5, HIS1_HALMA ;
DR   B8D111, HIS1_HALOH ;  B0R7E9, HIS1_HALS3 ;  Q9HN53, HIS1_HALSA ;
DR   Q18EV8, HIS1_HALWD ;  Q7VJU4, HIS1_HELHP ;  A4G9J2, HIS1_HERAR ;
DR   B4U858, HIS1_HYDS0 ;  A8AAI4, HIS1_IGNH4 ;  A6T382, HIS1_JANMA ;
DR   B5XPE8, HIS1_KLEP3 ;  A6TBC2, HIS1_KLEP7 ;  P05148, HIS1_KLEPN ;
DR   Q6CID6, HIS1_KLULA ;  B2GGU8, HIS1_KOCRD ;  Q039B0, HIS1_LACC3 ;
DR   B3WED6, HIS1_LACCB ;  Q02129, HIS1_LACLA ;  A2RKS3, HIS1_LACLM ;
DR   Q88UD9, HIS1_LACPL ;  B0SDL3, HIS1_LEPBA ;  Q04U38, HIS1_LEPBJ ;
DR   Q04ZI7, HIS1_LEPBL ;  B0SM42, HIS1_LEPBP ;  B1XX72, HIS1_LEPCP ;
DR   P62382, HIS1_LEPIC ;  Q8F6P1, HIS1_LEPIN ;  Q92E83, HIS1_LISIN ;
DR   C1L0J7, HIS1_LISMC ;  Q722Y2, HIS1_LISMF ;  B8DA57, HIS1_LISMH ;
DR   Q8Y9G0, HIS1_LISMO ;  A0AG20, HIS1_LISW6 ;  B1HVP7, HIS1_LYSSC ;
DR   Q2W1X8, HIS1_MAGSA ;  Q65RB0, HIS1_MANSM ;  A1U458, HIS1_MARAV ;
DR   Q0AP80, HIS1_MARMM ;  A6VY00, HIS1_MARMS ;  Q11LA2, HIS1_MESSB ;
DR   A6UTA7, HIS1_META3 ;  Q8TU56, HIS1_METAC ;  Q46CW7, HIS1_METBF ;
DR   Q12WC7, HIS1_METBU ;  Q606Q1, HIS1_METCA ;  Q1H4R9, HIS1_METFK ;
DR   B3E177, HIS1_METI4 ;  Q58601, HIS1_METJA ;  Q8TYD5, HIS1_METKA ;
DR   A4FXY0, HIS1_METM5 ;  A9AAZ7, HIS1_METM6 ;  A6VFN8, HIS1_METM7 ;
DR   Q8PWS3, HIS1_METMA ;  P60807, HIS1_METMP ;  A2SE03, HIS1_METPP ;
DR   A4YI31, HIS1_METS5 ;  O27550, HIS1_METTH ;  B0JK88, HIS1_MICAN ;
DR   C5CBK0, HIS1_MICLC ;  Q2RGV7, HIS1_MOOTA ;  A0QFA5, HIS1_MYCA1 ;
DR   P60760, HIS1_MYCBO ;  A1KKG4, HIS1_MYCBP ;  C1AQ37, HIS1_MYCBT ;
DR   A4TB83, HIS1_MYCGI ;  Q49776, HIS1_MYCLE ;  P60805, HIS1_MYCPA ;
DR   A3Q1A9, HIS1_MYCSJ ;  A1UHU3, HIS1_MYCSK ;  Q1B782, HIS1_MYCSS ;
DR   A5U4E7, HIS1_MYCTA ;  P60759, HIS1_MYCTU ;  Q3ITB2, HIS1_NATPD ;
DR   Q5F7E0, HIS1_NEIG1 ;  P64346, HIS1_NEIMA ;  P64347, HIS1_NEIMB ;
DR   A1KV03, HIS1_NEIMF ;  Q0AGS2, HIS1_NITEC ;  Q82W27, HIS1_NITEU ;
DR   Q1QIM4, HIS1_NITHX ;  Q2YAU4, HIS1_NITMU ;  Q3J7H0, HIS1_NITOC ;
DR   A6Q469, HIS1_NITSB ;  Q3SPH2, HIS1_NITWN ;  Q5YUV9, HIS1_NOCFA ;
DR   B2IY34, HIS1_NOSP7 ;  Q8YVL0, HIS1_NOSS1 ;  Q2G469, HIS1_NOVAD ;
DR   Q8ESR7, HIS1_OCEIH ;  A6X3C3, HIS1_OCHA4 ;  B6JIW1, HIS1_OLICO ;
DR   A6LAM0, HIS1_PARD8 ;  P57919, HIS1_PASMU ;  C6DF77, HIS1_PECCP ;
DR   Q3A132, HIS1_PELCD ;  Q3B6A2, HIS1_PELLD ;  B4SCC0, HIS1_PELPB ;
DR   A1AT72, HIS1_PELPD ;  A5D3N6, HIS1_PELTS ;  A9BJZ4, HIS1_PETMO ;
DR   Q7N6I0, HIS1_PHOLL ;  P62365, HIS1_PHOPR ;  A1VK36, HIS1_POLNA ;
DR   B4S561, HIS1_PROA2 ;  A3PBT4, HIS1_PROM0 ;  A2C117, HIS1_PROM1 ;
DR   A8G3S5, HIS1_PROM2 ;  A9BEI4, HIS1_PROM4 ;  A2BVM2, HIS1_PROM5 ;
DR   Q31BX4, HIS1_PROM9 ;  Q7VD22, HIS1_PROMA ;  B4ET04, HIS1_PROMH ;
DR   Q7V6G9, HIS1_PROMM ;  Q7V2C0, HIS1_PROMP ;  A2BQ41, HIS1_PROMS ;
DR   Q46GM0, HIS1_PROMT ;  A4SCX0, HIS1_PROVI ;  Q48EC8, HIS1_PSE14 ;
DR   A6VBC2, HIS1_PSEA7 ;  B7UZY8, HIS1_PSEA8 ;  Q02GZ2, HIS1_PSEAB ;
DR   Q9HVW8, HIS1_PSEAE ;  Q1IE99, HIS1_PSEE4 ;  Q4KI74, HIS1_PSEF5 ;
DR   C3K8X5, HIS1_PSEFS ;  A4XQN5, HIS1_PSEMY ;  A5VZ55, HIS1_PSEP1 ;
DR   Q3KHZ3, HIS1_PSEPF ;  B0KQJ4, HIS1_PSEPG ;  Q88P87, HIS1_PSEPK ;
DR   B1JBC2, HIS1_PSEPW ;  Q87WV4, HIS1_PSESM ;  Q4ZNV8, HIS1_PSEU2 ;
DR   Q4FQF7, HIS1_PSYA2 ;  A1SVD5, HIS1_PSYIN ;  Q8ZY36, HIS1_PYRAE ;
DR   A3MSF5, HIS1_PYRCJ ;  Q8U0D4, HIS1_PYRFU ;  A1RTU8, HIS1_PYRIL ;
DR   Q5JFR6, HIS1_PYRKO ;  Q1LIA5, HIS1_RALME ;  B3PRB1, HIS1_RHIE6 ;
DR   Q2KC02, HIS1_RHIEC ;  Q987S8, HIS1_RHILO ;  Q92RR6, HIS1_RHIME ;
DR   C3MGT4, HIS1_RHISN ;  Q7URL0, HIS1_RHOBA ;  C0ZZV7, HIS1_RHOE4 ;
DR   Q21U97, HIS1_RHOFD ;  C1ASQ7, HIS1_RHOOB ;  Q2IZ07, HIS1_RHOP2 ;
DR   Q07TA7, HIS1_RHOP5 ;  P60806, HIS1_RHOPA ;  Q20X96, HIS1_RHOPB ;
DR   Q131A2, HIS1_RHOPS ;  B3QIF6, HIS1_RHOPT ;  Q2RQM6, HIS1_RHORT ;
DR   O08385, HIS1_RHOS4 ;  Q0SIE9, HIS1_RHOSR ;  Q1AX11, HIS1_RUBXD ;
DR   A1AWP5, HIS1_RUTMC ;  Q21FV3, HIS1_SACD2 ;  A4FBW8, HIS1_SACEN ;
DR   B5EX38, HIS1_SALA4 ;  Q57MS4, HIS1_SALCH ;  B5FM40, HIS1_SALDC ;
DR   B5QZL1, HIS1_SALEP ;  B5RBR1, HIS1_SALG2 ;  B4T9N3, HIS1_SALHS ;
DR   B4SX40, HIS1_SALNS ;  Q5PDP2, HIS1_SALPA ;  C0Q1K3, HIS1_SALPC ;
DR   B5BFC1, HIS1_SALPK ;  Q2S4L6, HIS1_SALRD ;  B4TMR4, HIS1_SALSV ;
DR   Q8Z5K1, HIS1_SALTI ;  A4X642, HIS1_SALTO ;  P00499, HIS1_SALTY ;
DR   P40373, HIS1_SCHPO ;  A8GC80, HIS1_SERP5 ;  B8E9A5, HIS1_SHEB2 ;
DR   A3D5A5, HIS1_SHEB5 ;  A6WP16, HIS1_SHEB8 ;  A9L4B4, HIS1_SHEB9 ;
DR   Q12NS4, HIS1_SHEDO ;  Q083J5, HIS1_SHEFN ;  B0TRH1, HIS1_SHEHH ;
DR   A3QF15, HIS1_SHELP ;  Q8EFB0, HIS1_SHEON ;  A8H5D9, HIS1_SHEPA ;
DR   B8CR48, HIS1_SHEPW ;  A0KWB6, HIS1_SHESA ;  A8FWC5, HIS1_SHESH ;
DR   Q0HUP0, HIS1_SHESR ;  B1KRG9, HIS1_SHEWM ;  B2TYG1, HIS1_SHIB3 ;
DR   Q323J3, HIS1_SHIBS ;  Q32EE8, HIS1_SHIDS ;  Q0T3A8, HIS1_SHIF8 ;
DR   Q83KJ7, HIS1_SHIFL ;  Q3Z0G6, HIS1_SHISS ;  A6U6I2, HIS1_SINMW ;
DR   Q2NTX0, HIS1_SODGM ;  Q01ZU0, HIS1_SOLUE ;  A9GD69, HIS1_SORC5 ;
DR   Q1GRI4, HIS1_SPHAL ;  A5VA16, HIS1_SPHWW ;  A7X770, HIS1_STAA1 ;
DR   A6U564, HIS1_STAA2 ;  Q2FDI2, HIS1_STAA3 ;  Q2FUT7, HIS1_STAA8 ;
DR   A5IWA6, HIS1_STAA9 ;  Q2YZB3, HIS1_STAAB ;  Q5HCL8, HIS1_STAAC ;
DR   A6QKG7, HIS1_STAAE ;  P64348, HIS1_STAAM ;  P64349, HIS1_STAAN ;
DR   Q6GDC5, HIS1_STAAR ;  Q6G5Z6, HIS1_STAAS ;  A8Z5H9, HIS1_STAAT ;
DR   P64350, HIS1_STAAW ;  B9DQ89, HIS1_STACT ;  Q5HKN7, HIS1_STAEQ ;
DR   Q8CTV1, HIS1_STAES ;  Q4A043, HIS1_STAS1 ;  Q827L7, HIS1_STRAW ;
DR   Q8CK28, HIS1_STRCO ;  A8AY29, HIS1_STRGC ;  B4STN6, HIS1_STRM5 ;
DR   B2FPL8, HIS1_STRMK ;  Q8DTQ6, HIS1_STRMU ;  A3CNT5, HIS1_STRSV ;
DR   Q03K77, HIS1_STRTD ;  Q4J8J2, HIS1_SULAC ;  Q30S64, HIS1_SULDN ;
DR   A6Q7C5, HIS1_SULNB ;  O33771, HIS1_SULSO ;  Q970Z3, HIS1_SULTO ;
DR   Q67KH5, HIS1_SYMTH ;  Q31Q54, HIS1_SYNE7 ;  Q2JL97, HIS1_SYNJB ;
DR   B1XPZ8, HIS1_SYNP2 ;  Q5N426, HIS1_SYNP6 ;  A5GJK6, HIS1_SYNPW ;
DR   Q7U5Z9, HIS1_SYNPX ;  A5GS82, HIS1_SYNR3 ;  Q3AYI1, HIS1_SYNS9 ;
DR   Q3AL07, HIS1_SYNSC ;  Q0AW37, HIS1_SYNWW ;  Q55503, HIS1_SYNY3 ;
DR   C5BSW3, HIS1_TERTT ;  Q8DMD9, HIS1_THEEB ;  C5A797, HIS1_THEGJ ;
DR   Q9X0D2, HIS1_THEMA ;  B9K9R7, HIS1_THENN ;  B1YAM9, HIS1_THENV ;
DR   B6YWA4, HIS1_THEON ;  A5INE0, HIS1_THEP1 ;  B0K733, HIS1_THEP3 ;
DR   B0K623, HIS1_THEPX ;  B1L867, HIS1_THESQ ;  P62381, HIS1_THET2 ;
DR   Q5SM15, HIS1_THET8 ;  Q8R881, HIS1_THETN ;  B5YJ68, HIS1_THEYD ;
DR   Q31GZ0, HIS1_THICR ;  Q3SHP3, HIS1_THIDA ;  C4LFH8, HIS1_TOLAT ;
DR   Q0W6K3, HIS1_UNCMA ;  C5CQI9, HIS1_VARPS ;  A5CWJ0, HIS1_VESOH ;
DR   Q9KSX4, HIS1_VIBCH ;  Q5E639, HIS1_VIBF1 ;  B5FD98, HIS1_VIBFM ;
DR   A7MX14, HIS1_VIBHB ;  Q87QL2, HIS1_VIBPA ;  Q8D8P9, HIS1_VIBVU ;
DR   Q7MLS7, HIS1_VIBVY ;  Q7M9N0, HIS1_WOLSU ;  Q8PLH0, HIS1_XANAC ;
DR   Q3BUF8, HIS1_XANC5 ;  Q4UU39, HIS1_XANC8 ;  B0RSL3, HIS1_XANCB ;
DR   Q8P9P3, HIS1_XANCP ;  Q2P3K4, HIS1_XANOM ;  B2SKN9, HIS1_XANOP ;
DR   Q5H0L2, HIS1_XANOR ;  B2I5Y2, HIS1_XYLF2 ;  Q9PBC4, HIS1_XYLFA ;
DR   B0U3B4, HIS1_XYLFM ;  Q87C28, HIS1_XYLFT ;  Q99145, HIS1_YARLI ;
DR   P00498, HIS1_YEAST ;  A1JTV7, HIS1_YERE8 ;  A7FJG9, HIS1_YERP3 ;
DR   Q1C9Q9, HIS1_YERPA ;  B2JZN0, HIS1_YERPB ;  Q8ZFX4, HIS1_YERPE ;
DR   A9R2K3, HIS1_YERPG ;  Q1CGX2, HIS1_YERPN ;  A4TKK2, HIS1_YERPP ;
DR   Q66C48, HIS1_YERPS ;  B1JPV9, HIS1_YERPY ;  Q9RH04, HIS1_ZYMMO ;
//
ID   2.4.2.18
DE   Anthranilate phosphoribosyltransferase.
AN   Phosphoribosyl-anthranilate diphosphorylase.
AN   Phosphoribosyl-anthranilate pyrophosphorylase.
CA   N-(5-phospho-D-ribosyl)-anthranilate + diphosphate = anthranilate +
CA   5-phospho-alpha-D-ribose 1-diphosphate.
CC   -!- In some organisms, this enzyme is part of a multifunctional protein
CC       together with one or more components of the system for biosynthesis
CC       of tryptophan (EC 4.1.1.48, EC 4.1.3.27, EC 4.2.1.20,
CC       and EC 5.3.1.24).
DR   O28668, TRPCD_ARCFU;  Q8YZP8, TRPD1_NOSS1;  Q8XVE7, TRPD1_RALSO;
DR   O68608, TRPD1_STRCO;  Q8YXQ9, TRPD2_NOSS1;  Q8XS00, TRPD2_RALSO;
DR   Q9Z4W9, TRPD2_STRCO;  A1TJQ1, TRPD_ACIAC ;  P00500, TRPD_ACIAD ;
DR   Q1IJR5, TRPD_ACIBL ;  B0VUS1, TRPD_ACIBS ;  A3M784, TRPD_ACIBT ;
DR   B0VBS2, TRPD_ACIBY ;  A0LTH9, TRPD_ACIC1 ;  B9MBS3, TRPD_ACIET ;
DR   B7JBC1, TRPD_ACIF2 ;  B5ERI3, TRPD_ACIF5 ;  A1W2Z7, TRPD_ACISJ ;
DR   A3N1G7, TRPD_ACTP2 ;  B3GY52, TRPD_ACTP7 ;  B0BQA6, TRPD_ACTPJ ;
DR   A6VNT3, TRPD_ACTSZ ;  A0KMC8, TRPD_AERHH ;  Q9Y8T2, TRPD_AERPE ;
DR   A4SKT3, TRPD_AERS4 ;  B9JFD7, TRPD_AGRRK ;  Q8UER8, TRPD_AGRT5 ;
DR   B9JX63, TRPD_AGRVS ;  Q0VMX5, TRPD_ALCBS ;  Q0A6E7, TRPD_ALHEH ;
DR   A6TM73, TRPD_ALKMQ ;  B8JAL5, TRPD_ANAD2 ;  Q2IGV6, TRPD_ANADE ;
DR   A7H793, TRPD_ANADF ;  B4UHD1, TRPD_ANASK ;  B9MKD0, TRPD_ANATD ;
DR   Q3M4T0, TRPD_ANAVT ;  O66576, TRPD_AQUAE ;  Q02166, TRPD_ARATH ;
DR   Q5P2G2, TRPD_AROAE ;  A1R6T5, TRPD_ARTAT ;  A0JX18, TRPD_ARTS2 ;
DR   P26924, TRPD_AZOBR ;  A8I839, TRPD_AZOC5 ;  A1KAT3, TRPD_AZOSB ;
DR   C1DHY8, TRPD_AZOVD ;  A7Z619, TRPD_BACA2 ;  C3P3T7, TRPD_BACAA ;
DR   C3LAW1, TRPD_BACAC ;  A0RB61, TRPD_BACAH ;  Q81TM1, TRPD_BACAN ;
DR   B7JES7, TRPD_BACC0 ;  Q73BR0, TRPD_BACC1 ;  B7IM73, TRPD_BACC2 ;
DR   C1ELE7, TRPD_BACC3 ;  B7HGZ8, TRPD_BACC4 ;  B7I0E9, TRPD_BACC7 ;
DR   P30525, TRPD_BACCA ;  B9IU35, TRPD_BACCQ ;  Q81GG8, TRPD_BACCR ;
DR   Q63ED0, TRPD_BACCZ ;  Q5LBZ5, TRPD_BACFN ;  Q64SX6, TRPD_BACFR ;
DR   Q9KCB3, TRPD_BACHD ;  Q6HLU7, TRPD_BACHK ;  Q65I32, TRPD_BACLD ;
DR   P70936, TRPD_BACMQ ;  A8FEK1, TRPD_BACP2 ;  P18261, TRPD_BACPU ;
DR   Q5WGS4, TRPD_BACSK ;  P03947, TRPD_BACSU ;  Q8AAD5, TRPD_BACTN ;
DR   A6L7M8, TRPD_BACV8 ;  A9VJV9, TRPD_BACWK ;  B2IKP4, TRPD_BEII9 ;
DR   Q494D8, TRPD_BLOPB ;  Q2KU98, TRPD_BORA1 ;  Q7WEK7, TRPD_BORBR ;
DR   Q7W388, TRPD_BORPA ;  A9HY12, TRPD_BORPD ;  Q7VU66, TRPD_BORPE ;
DR   P94326, TRPD_BRAJA ;  A5EK24, TRPD_BRASB ;  A4YVD5, TRPD_BRASO ;
DR   C0ZCE2, TRPD_BREBN ;  B2S5Z0, TRPD_BRUA1 ;  Q2YRR5, TRPD_BRUA2 ;
DR   Q57CZ9, TRPD_BRUAB ;  A9M5F3, TRPD_BRUC2 ;  C0RJB0, TRPD_BRUMB ;
DR   Q8YHF7, TRPD_BRUME ;  A5VQR4, TRPD_BRUO2 ;  B0CGT8, TRPD_BRUSI ;
DR   Q8G0F5, TRPD_BRUSU ;  B8D972, TRPD_BUCA5 ;  P57367, TRPD_BUCAI ;
DR   P42392, TRPD_BUCAP ;  B8D7H6, TRPD_BUCAT ;  P59415, TRPD_BUCBP ;
DR   O68426, TRPD_BUCDN ;  Q9RQ35, TRPD_BUCMH ;  Q44602, TRPD_BUCSC ;
DR   B1YSF6, TRPD_BURA4 ;  Q1BSD3, TRPD_BURCA ;  B1JUU6, TRPD_BURCC ;
DR   A0K459, TRPD_BURCH ;  B4E7A8, TRPD_BURCJ ;  Q0BIM7, TRPD_BURCM ;
DR   Q845X9, TRPD_BURM1 ;  A3MFQ3, TRPD_BURM7 ;  A2RYI2, TRPD_BURM9 ;
DR   Q62DC9, TRPD_BURMA ;  A1UW99, TRPD_BURMS ;  A3NZP5, TRPD_BURP0 ;
DR   Q3JNB1, TRPD_BURP1 ;  A3NDZ2, TRPD_BURP6 ;  B2JHI7, TRPD_BURP8 ;
DR   Q63QH1, TRPD_BURPS ;  Q39JZ6, TRPD_BURS3 ;  Q2SUI1, TRPD_BURTA ;
DR   A4JB68, TRPD_BURVG ;  Q13TW5, TRPD_BURXL ;  A8MDL8, TRPD_CALMQ ;
DR   A4XLM7, TRPD_CALS8 ;  Q3ABS0, TRPD_CARHZ ;  B8GWP8, TRPD_CAUCN ;
DR   Q9A728, TRPD_CAUCR ;  B0SYZ3, TRPD_CAUSK ;  B3PLP1, TRPD_CELJU ;
DR   A0RX34, TRPD_CENSY ;  A9WCH7, TRPD_CHLAA ;  B8G5C5, TRPD_CHLAD ;
DR   Q3APT3, TRPD_CHLCH ;  Q822W6, TRPD_CHLCV ;  Q254S7, TRPD_CHLFF ;
DR   B3EH38, TRPD_CHLL2 ;  B3QM44, TRPD_CHLP8 ;  B3EMT4, TRPD_CHLPB ;
DR   A1BE13, TRPD_CHLPD ;  B9LEV9, TRPD_CHLSY ;  B3QUY6, TRPD_CHLT3 ;
DR   Q8KC17, TRPD_CHLTE ;  Q1QV38, TRPD_CHRSD ;  Q7NW17, TRPD_CHRVO ;
DR   A5CS25, TRPD_CLAM3 ;  B0REA1, TRPD_CLAMS ;  Q97EF2, TRPD_CLOAB ;
DR   A6LU93, TRPD_CLOB8 ;  B8I0U9, TRPD_CLOCE ;  B9E148, TRPD_CLOK1 ;
DR   A5N7N7, TRPD_CLOK5 ;  A9KL44, TRPD_CLOPH ;  A3DDS8, TRPD_CLOTH ;
DR   Q47YC2, TRPD_COLP3 ;  C3PKY4, TRPD_CORA7 ;  Q6NEC1, TRPD_CORDI ;
DR   Q8FLJ8, TRPD_COREF ;  A4QI74, TRPD_CORGB ;  P06559, TRPD_CORGL ;
DR   Q4JWC7, TRPD_CORJK ;  Q0K6I1, TRPD_CUPNH ;  Q46WU8, TRPD_CUPPJ ;
DR   B7JX56, TRPD_CYAP8 ;  Q11PY2, TRPD_CYTH3 ;  Q47AC6, TRPD_DECAR ;
DR   Q3Z6G6, TRPD_DEHE1 ;  Q3ZZ15, TRPD_DEHSC ;  Q1IZP8, TRPD_DEIGD ;
DR   Q9RTJ5, TRPD_DEIRA ;  A9BS05, TRPD_DELAS ;  B8FA41, TRPD_DESAA ;
DR   C6C1D5, TRPD_DESAD ;  B1I3Z8, TRPD_DESAP ;  Q30VM1, TRPD_DESDG ;
DR   B8FVH5, TRPD_DESHD ;  Q24SK4, TRPD_DESHY ;  A8ZZX1, TRPD_DESOH ;
DR   Q6AMS5, TRPD_DESPS ;  A4J146, TRPD_DESRM ;  B8DM45, TRPD_DESVM ;
DR   B5YD05, TRPD_DICT6 ;  B8DZP4, TRPD_DICTD ;  A8LMJ6, TRPD_DINSH ;
DR   P12320, TRPD_ERWCA ;  Q6D4U2, TRPD_ERWCT ;  B2VKT4, TRPD_ERWT9 ;
DR   Q2NA97, TRPD_ERYLH ;  C4Z111, TRPD_EUBE2 ;  C4ZI69, TRPD_EUBR3 ;
DR   B1YLS1, TRPD_EXIS2 ;  A5FA70, TRPD_FLAJ1 ;  A6GWZ4, TRPD_FLAPJ ;
DR   Q0RFI3, TRPD_FRAAA ;  B0TWF2, TRPD_FRAP2 ;  A7NF00, TRPD_FRATF ;
DR   B2SEF6, TRPD_FRATM ;  A0Q8R1, TRPD_FRATN ;  Q0BJW6, TRPD_FRATO ;
DR   A4J0E5, TRPD_FRATW ;  B5EBU6, TRPD_GEOBB ;  Q5KXU8, TRPD_GEOKA ;
DR   B3E5V8, TRPD_GEOLS ;  Q39SQ6, TRPD_GEOMG ;  Q9X6J5, TRPD_GEOSE ;
DR   B9M5M2, TRPD_GEOSF ;  Q74AH4, TRPD_GEOSL ;  C6DYM5, TRPD_GEOSM ;
DR   C5D3D7, TRPD_GEOSW ;  A4IQ85, TRPD_GEOTN ;  A5GES2, TRPD_GEOUR ;
DR   Q7NGU2, TRPD_GLOVI ;  Q5FNM7, TRPD_GLUOX ;  Q0BTY4, TRPD_GRABC ;
DR   A0M4T1, TRPD_GRAFK ;  Q4QKA1, TRPD_HAEI8 ;  A5UBZ6, TRPD_HAEIE ;
DR   A5UEN6, TRPD_HAEIG ;  P43858, TRPD_HAEIN ;  B8F815, TRPD_HAEPS ;
DR   B0UU36, TRPD_HAES2 ;  Q2S999, TRPD_HAHCH ;  A1WYT2, TRPD_HALHL ;
DR   B9LQ96, TRPD_HALLT ;  Q5V211, TRPD_HALMA ;  B0R622, TRPD_HALS3 ;
DR   Q9HPG3, TRPD_HALSA ;  P52562, TRPD_HALVD ;  Q18FI8, TRPD_HALWD ;
DR   Q17ZP2, TRPD_HELAH ;  B6JNC0, TRPD_HELP2 ;  B5Z8S5, TRPD_HELPG ;
DR   Q1CRX3, TRPD_HELPH ;  Q9ZJU7, TRPD_HELPJ ;  B2UV44, TRPD_HELPS ;
DR   P56737, TRPD_HELPY ;  A9B148, TRPD_HERA2 ;  A4G1P5, TRPD_HERAR ;
DR   Q0C1A1, TRPD_HYPNA ;  Q5QX82, TRPD_IDILO ;  A8ACG6, TRPD_IGNH4 ;
DR   A6SUH6, TRPD_JANMA ;  Q28R66, TRPD_JANSC ;  Q03CY0, TRPD_LACC3 ;
DR   P17170, TRPD_LACCA ;  B3W6W9, TRPD_LACCB ;  Q02000, TRPD_LACLA ;
DR   A2RK17, TRPD_LACLM ;  Q02YA8, TRPD_LACLS ;  Q88WI3, TRPD_LACPL ;
DR   C1D7P3, TRPD_LARHH ;  Q5X6R9, TRPD_LEGPA ;  A5IG81, TRPD_LEGPC ;
DR   Q5ZX98, TRPD_LEGPH ;  Q5WY74, TRPD_LEGPL ;  Q6AFI7, TRPD_LEIXX ;
DR   Q04R23, TRPD_LEPBJ ;  Q04ZD2, TRPD_LEPBL ;  B1Y7I3, TRPD_LEPCP ;
DR   Q72PD0, TRPD_LEPIC ;  Q8F708, TRPD_LEPIN ;  Q03WZ9, TRPD_LEUMM ;
DR   Q92B78, TRPD_LISIN ;  C1KVS8, TRPD_LISMC ;  Q71Z37, TRPD_LISMF ;
DR   B8DHB1, TRPD_LISMH ;  Q8Y6Q3, TRPD_LISMO ;  A0AJ83, TRPD_LISW6 ;
DR   Q2W3A9, TRPD_MAGSA ;  Q65TF2, TRPD_MANSM ;  A1U6H0, TRPD_MARAV ;
DR   Q0APU5, TRPD_MARMM ;  A6VU64, TRPD_MARMS ;  Q11HU2, TRPD_MESSB ;
DR   A6UW21, TRPD_META3 ;  Q8TLP5, TRPD_METAC ;  A7I4T7, TRPD_METB6 ;
DR   Q465F3, TRPD_METBF ;  Q12TL1, TRPD_METBU ;  B7KUV9, TRPD_METC4 ;
DR   Q604F8, TRPD_METCA ;  A9W900, TRPD_METEP ;  Q1GYF5, TRPD_METFK ;
DR   Q2FKX5, TRPD_METHJ ;  Q57686, TRPD_METJA ;  Q8TXJ5, TRPD_METKA ;
DR   A2STA7, TRPD_METLZ ;  A4FXH2, TRPD_METM5 ;  A9AAU1, TRPD_METM6 ;
DR   A6VFU3, TRPD_METM7 ;  Q8PT97, TRPD_METMA ;  A3CRK8, TRPD_METMJ ;
DR   Q6LYI4, TRPD_METMP ;  B8IP99, TRPD_METNO ;  B1Z9R9, TRPD_METPB ;
DR   B8GJ30, TRPD_METPE ;  A2SLH5, TRPD_METPP ;  B1M5Q2, TRPD_METRJ ;
DR   A5UMC1, TRPD_METS3 ;  B0U7Z5, TRPD_METS4 ;  A4YHE2, TRPD_METS5 ;
DR   B8EJS2, TRPD_METSB ;  Q2NFE4, TRPD_METST ;  O27698, TRPD_METTH ;
DR   P26925, TRPD_METTM ;  A6UP19, TRPD_METVS ;  Q2RIT6, TRPD_MOOTA ;
DR   P66993, TRPD_MYCBO ;  A1KKN4, TRPD_MYCBP ;  C1AQA7, TRPD_MYCBT ;
DR   A4TBH5, TRPD_MYCGI ;  B8ZQM2, TRPD_MYCLB ;  O69581, TRPD_MYCLE ;
DR   B2HGW0, TRPD_MYCMM ;  Q73YM4, TRPD_MYCPA ;  A0R048, TRPD_MYCS2 ;
DR   A3Q1Q2, TRPD_MYCSJ ;  A1UI88, TRPD_MYCSK ;  Q1B6T7, TRPD_MYCSS ;
DR   A5U4M0, TRPD_MYCTA ;  P66992, TRPD_MYCTU ;  A0PTM6, TRPD_MYCUA ;
DR   A1TB00, TRPD_MYCVP ;  Q1CZH6, TRPD_MYXXD ;  Q3IQ38, TRPD_NATPD ;
DR   Q5F7H5, TRPD_NEIG1 ;  A9M4G6, TRPD_NEIM0 ;  P66994, TRPD_NEIMA ;
DR   P66995, TRPD_NEIMB ;  A1KTN4, TRPD_NEIMF ;  Q0AJP9, TRPD_NITEC ;
DR   Q82Y74, TRPD_NITEU ;  Q1QMJ8, TRPD_NITHX ;  A9A298, TRPD_NITMS ;
DR   Q2Y5W9, TRPD_NITMU ;  Q3J897, TRPD_NITOC ;  Q3SRJ4, TRPD_NITWN ;
DR   Q5YZ21, TRPD_NOCFA ;  A1SLE8, TRPD_NOCSJ ;  Q2G6R1, TRPD_NOVAD ;
DR   Q8ESU1, TRPD_OCEIH ;  A6X0L1, TRPD_OCHA4 ;  B6JG28, TRPD_OLICO ;
DR   A1B3Y5, TRPD_PARDP ;  A7HXZ5, TRPD_PARL1 ;  P57856, TRPD_PASMU ;
DR   C6DGZ7, TRPD_PECCP ;  Q3A6L6, TRPD_PELCD ;  Q3B2H3, TRPD_PELLD ;
DR   B4SE13, TRPD_PELPB ;  A1ALX3, TRPD_PELPD ;  A5D1S5, TRPD_PELTS ;
DR   Q4FM53, TRPD_PELUB ;  C0QR68, TRPD_PERMH ;  A9BHQ6, TRPD_PETMO ;
DR   B4RBX4, TRPD_PHEZH ;  Q7N488, TRPD_PHOLL ;  Q6LPA6, TRPD_PHOPR ;
DR   Q6L273, TRPD_PICTO ;  B1XSZ2, TRPD_POLNS ;  Q123F3, TRPD_POLSJ ;
DR   A4SV53, TRPD_POLSQ ;  B4S5K5, TRPD_PROA2 ;  A3PCQ4, TRPD_PROM0 ;
DR   A2C1X5, TRPD_PROM1 ;  A8G4M3, TRPD_PROM2 ;  A9B9W1, TRPD_PROM4 ;
DR   A2BWT1, TRPD_PROM5 ;  Q31B38, TRPD_PROM9 ;  Q7VCJ6, TRPD_PROMA ;
DR   B4EWH5, TRPD_PROMH ;  Q7TV05, TRPD_PROMM ;  Q7TU90, TRPD_PROMP ;
DR   A2BQY1, TRPD_PROMS ;  Q46L78, TRPD_PROMT ;  A4SFZ6, TRPD_PROVI ;
DR   Q48NP8, TRPD_PSE14 ;  Q15RZ7, TRPD_PSEA6 ;  A6UZF1, TRPD_PSEA7 ;
DR   B7V608, TRPD_PSEA8 ;  Q02TB6, TRPD_PSEAB ;  P20574, TRPD_PSEAE ;
DR   Q1IG00, TRPD_PSEE4 ;  Q4K502, TRPD_PSEF5 ;  C3K308, TRPD_PSEFS ;
DR   Q3IKY4, TRPD_PSEHT ;  A4XZC6, TRPD_PSEMY ;  A5VXL4, TRPD_PSEP1 ;
DR   Q3K5V3, TRPD_PSEPF ;  B0KJB2, TRPD_PSEPG ;  Q88QR7, TRPD_PSEPK ;
DR   P20575, TRPD_PSEPU ;  B1JE35, TRPD_PSEPW ;  Q88A04, TRPD_PSESM ;
DR   Q4ZML2, TRPD_PSEU2 ;  A4VHK0, TRPD_PSEU5 ;  A1STT2, TRPD_PSYIN ;
DR   A5WFZ6, TRPD_PSYWF ;  Q9V1G4, TRPD_PYRAB ;  Q8ZV45, TRPD_PYRAE ;
DR   A4WKR0, TRPD_PYRAR ;  A3MVG6, TRPD_PYRCJ ;  Q8U089, TRPD_PYRFU ;
DR   A1RVT0, TRPD_PYRIL ;  Q9YGB4, TRPD_PYRKO ;  Q1LIH4, TRPD_RALME ;
DR   B2UDK8, TRPD_RALPJ ;  B3Q0L2, TRPD_RHIE6 ;  Q2K880, TRPD_RHIEC ;
DR   Q1MGE2, TRPD_RHIL3 ;  Q98ME4, TRPD_RHILO ;  B5ZPY6, TRPD_RHILW ;
DR   Q92PS0, TRPD_RHIME ;  C3MCF3, TRPD_RHISN ;  Q7UYS5, TRPD_RHOBA ;
DR   Q21SE7, TRPD_RHOFD ;  C1AU95, TRPD_RHOOB ;  Q2IWB1, TRPD_RHOP2 ;
DR   Q07NF5, TRPD_RHOP5 ;  Q6N5T0, TRPD_RHOPA ;  Q215B8, TRPD_RHOPB ;
DR   Q136D3, TRPD_RHOPS ;  B3Q6M8, TRPD_RHOPT ;  Q2RT49, TRPD_RHORT ;
DR   A3PHK8, TRPD_RHOS1 ;  Q9ZFA8, TRPD_RHOS4 ;  A4WX68, TRPD_RHOS5 ;
DR   B9KMV1, TRPD_RHOSK ;  Q0SHN1, TRPD_RHOSR ;  A7NL64, TRPD_ROSCS ;
DR   Q163Y0, TRPD_ROSDO ;  A5UT95, TRPD_ROSS1 ;  Q1AU89, TRPD_RUBXD ;
DR   A1AVF1, TRPD_RUTMC ;  Q21MR4, TRPD_SACD2 ;  A4FAC5, TRPD_SACEN ;
DR   A8LYC4, TRPD_SALAI ;  Q2S1Z6, TRPD_SALRD ;  A4X9Z2, TRPD_SALTO ;
DR   O60122, TRPD_SCHPO ;  P12321, TRPD_SERMA ;  A8GF80, TRPD_SERP5 ;
DR   A1S7I0, TRPD_SHEAM ;  A3D628, TRPD_SHEB5 ;  A6WPW9, TRPD_SHEB8 ;
DR   A9KTR5, TRPD_SHEB9 ;  Q12LE4, TRPD_SHEDO ;  Q084N6, TRPD_SHEFN ;
DR   A3QF71, TRPD_SHELP ;  Q8ECV2, TRPD_SHEON ;  A4Y843, TRPD_SHEPC ;
DR   A0KVD3, TRPD_SHESA ;  Q0HK79, TRPD_SHESM ;  Q0HWI1, TRPD_SHESR ;
DR   A1RIE5, TRPD_SHESW ;  Q5LRH8, TRPD_SILPO ;  Q1GHJ3, TRPD_SILST ;
DR   A6U9C4, TRPD_SINMW ;  Q2NT50, TRPD_SODGM ;  Q021N5, TRPD_SOLUE ;
DR   A9F0C1, TRPD_SORC5 ;  Q1GUW8, TRPD_SPHAL ;  A7X232, TRPD_STAA1 ;
DR   A6U1J1, TRPD_STAA2 ;  Q2FH67, TRPD_STAA3 ;  Q2FYR7, TRPD_STAA8 ;
DR   A5ISQ1, TRPD_STAA9 ;  Q9RL77, TRPD_STAAC ;  A6QGS1, TRPD_STAAE ;
DR   P66996, TRPD_STAAM ;  P66997, TRPD_STAAN ;  Q6G9J0, TRPD_STAAS ;
DR   P66998, TRPD_STAAW ;  B9DP50, TRPD_STACT ;  Q5HPH3, TRPD_STAEQ ;
DR   Q8CSN6, TRPD_STAES ;  Q4L676, TRPD_STAHJ ;  Q49XH5, TRPD_STAS1 ;
DR   Q82AK1, TRPD_STRAW ;  A8AW02, TRPD_STRGC ;  B1VZR5, TRPD_STRGG ;
DR   B4SLE9, TRPD_STRM5 ;  B2FKL2, TRPD_STRMK ;  Q8DVF6, TRPD_STRMU ;
DR   Q04IY6, TRPD_STRP2 ;  B5E7M6, TRPD_STRP4 ;  C1C969, TRPD_STRP7 ;
DR   B1I7T0, TRPD_STRPI ;  B8ZN62, TRPD_STRPJ ;  P66999, TRPD_STRPN ;
DR   B2ISS4, TRPD_STRPS ;  P67000, TRPD_STRR6 ;  A3CLL8, TRPD_STRSV ;
DR   Q5LYI4, TRPD_STRT1 ;  Q5M347, TRPD_STRT2 ;  Q03JB8, TRPD_STRTD ;
DR   C1CG45, TRPD_STRZJ ;  C1CMD6, TRPD_STRZP ;  C1CT54, TRPD_STRZT ;
DR   Q4J8X7, TRPD_SULAC ;  C3N5I8, TRPD_SULIA ;  C4KH54, TRPD_SULIK ;
DR   C3MPW2, TRPD_SULIL ;  C3MV89, TRPD_SULIM ;  C3NHL1, TRPD_SULIN ;
DR   C3NE52, TRPD_SULIY ;  P50384, TRPD_SULSO ;  B2V751, TRPD_SULSY ;
DR   Q971Z7, TRPD_SULTO ;  Q67PJ9, TRPD_SYMTH ;  Q31LB6, TRPD_SYNE7 ;
DR   A0LJ59, TRPD_SYNFM ;  Q2JWL5, TRPD_SYNJA ;  Q2JQ65, TRPD_SYNJB ;
DR   Q5N0L1, TRPD_SYNP6 ;  A5GKM1, TRPD_SYNPW ;  Q7TTV4, TRPD_SYNPX ;
DR   A5GTM6, TRPD_SYNR3 ;  Q0I9N0, TRPD_SYNS3 ;  Q3AXD5, TRPD_SYNS9 ;
DR   Q0B006, TRPD_SYNWW ;  P73617, TRPD_SYNY3 ;  C5BPA3, TRPD_TERTT ;
DR   Q9HK06, TRPD_THEAC ;  Q8DI76, TRPD_THEEB ;  Q47R55, TRPD_THEFY ;
DR   B0K8T3, TRPD_THEP3 ;  B0K2U2, TRPD_THEPX ;  B9KXB8, TRPD_THERP ;
DR   Q72HJ6, TRPD_THET2 ;  Q5SH88, TRPD_THET8 ;  P83827, TRPD_THETH ;
DR   Q8R9M6, TRPD_THETN ;  Q979V5, TRPD_THEVO ;  Q31J09, TRPD_THICR ;
DR   Q3SGS1, TRPD_THIDA ;  B8GNI1, TRPD_THISH ;  C4LC91, TRPD_TOLAT ;
DR   Q112P2, TRPD_TRIEI ;  B1GZB9, TRPD_UNCTG ;  A1WH74, TRPD_VEREI ;
DR   A5CXR3, TRPD_VESOH ;  A5F210, TRPD_VIBC3 ;  Q9KST4, TRPD_VIBCH ;
DR   A7MRZ7, TRPD_VIBHB ;  P22096, TRPD_VIBPA ;  Q8D8B4, TRPD_VIBVU ;
DR   Q7MM54, TRPD_VIBVY ;  Q8PQ48, TRPD_XANAC ;  Q3BYB6, TRPD_XANC5 ;
DR   Q4UZF9, TRPD_XANC8 ;  B0RMZ8, TRPD_XANCB ;  Q8PD71, TRPD_XANCP ;
DR   Q2NYD6, TRPD_XANOM ;  B2SL02, TRPD_XANOP ;  A7INK3, TRPD_XANP2 ;
DR   B2I6S4, TRPD_XYLF2 ;  Q9PGT6, TRPD_XYLFA ;  B0U1N9, TRPD_XYLFM ;
DR   Q87EX3, TRPD_XYLFT ;  P07285, TRPD_YEAST ;  A7FI31, TRPD_YERP3 ;
DR   Q1C7P0, TRPD_YERPA ;  B2K3W4, TRPD_YERPB ;  Q8ZEG7, TRPD_YERPE ;
DR   Q1CJ26, TRPD_YERPN ;  A4TJ65, TRPD_YERPP ;  Q66AK2, TRPD_YERPS ;
DR   B1JKS0, TRPD_YERPY ;  P00904, TRPG_ECOLI ;  P00905, TRPG_SALTY ;
DR   P00906, TRPG_SHIDY ;  Q08654, TRPG_THEMA ;
//
ID   2.4.2.19
DE   Nicotinate-nucleotide diphosphorylase (carboxylating).
AN   Nicotinate-nucleotide pyrophosphorylase (carboxylating).
AN   Quinolinate phosphoribosyltransferase (decarboxylating).
CA   Nicotinate D-ribonucleotide + diphosphate + CO(2) = pyridine-2,3-
CA   dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate.
DR   O28439, NADC_ARCFU ;  P39666, NADC_BACSU ;  Q3T063, NADC_BOVIN ;
DR   Q75JX0, NADC_DICDI ;  P30011, NADC_ECOLI ;  Q9ZJN2, NADC_HELPJ ;
DR   O25909, NADC_HELPY ;  Q15274, NADC_HUMAN ;  Q57916, NADC_METJA ;
DR   O27860, NADC_METTH ;  Q91X91, NADC_MOUSE ;  P46714, NADC_MYCLE ;
DR   O06594, NADC_MYCTU ;  A7SG73, NADC_NEMVE ;  P30819, NADC_PSEAE ;
DR   Q5I0M2, NADC_RAT   ;  P77938, NADC_RHORU ;  P30012, NADC_SALTY ;
DR   P74301, NADC_SYNY3 ;  P43619, NADC_YEAST ;
//
ID   2.4.2.20
DE   Dioxotetrahydropyrimidine phosphoribosyltransferase.
AN   Dioxotetrahydropyrimidine-ribonucleotide diphosphorylase.
AN   Dioxotetrahydropyrimidine-ribonucleotide pyrophosphorylase.
CA   A 2,4-dioxotetrahydropyrimidine D-ribonucleotide + diphosphate = a 2,4-
CA   dioxotetrahydropyrimidine + 5-phospho-alpha-D-ribose 1-diphosphate.
CC   -!- Acts, in the reverse direction, on uracil and other pyrimidines and
CC       pteridines containing a 2,4-diketo structure.
//
ID   2.4.2.21
DE   Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase.
AN   N(1)-alpha-phosphoribosyltransferase.
AN   Nicotinate mononucleotide-dimethylbenzimidazole
AN   phosphoribosyltransferase.
CA   Beta-nicotinate D-ribonucleotide + 5,6-dimethylbenzimidazole = nicotinate
CA   + alpha-ribazole 5'-phosphate.
CC   -!- Also acts on benzimidazole, and the clostridial enzyme acts on
CC       adenine to form 7-alpha-D-ribosyladenine 5'-phosphate.
CC   -!- The product of the reaction, alpha-ribazole 5'-phosphate, forms part
CC       of the corrin biosynthesis pathway and is a substrate for EC 2.7.8.2.
CC   -!- It can also be dephosphorylated to form alpha-ribazole by the action
CC       of EC 3.1.3.73.
DR   B9JG15, COBT_AGRRK ;  Q8UE71, COBT_AGRT5 ;  B9JW09, COBT_AGRVS ;
DR   A6TKH4, COBT_ALKMQ ;  Q5P2R4, COBT_AROAE ;  A1KBH0, COBT_AZOSB ;
DR   C1DPN9, COBT_AZOVD ;  Q5LCE6, COBT_BACFN ;  Q64TE4, COBT_BACFR ;
DR   Q9KG31, COBT_BACHD ;  A6L518, COBT_BACV8 ;  Q89Q54, COBT_BRAJA ;
DR   A5EGF4, COBT_BRASB ;  A4YXK4, COBT_BRASO ;  B2S5A1, COBT_BRUA1 ;
DR   Q2YNK7, COBT_BRUA2 ;  Q57DN9, COBT_BRUAB ;  A9MAP0, COBT_BRUC2 ;
DR   C0RIK0, COBT_BRUMB ;  Q8YGQ9, COBT_BRUME ;  B0CLJ2, COBT_BRUSI ;
DR   Q8G155, COBT_BRUSU ;  A9WIQ7, COBT_CHLAA ;  B8G806, COBT_CHLAD ;
DR   Q3ARQ5, COBT_CHLCH ;  B3QNS6, COBT_CHLP8 ;  A1BF69, COBT_CHLPD ;
DR   B9LKQ0, COBT_CHLSY ;  Q8KDU8, COBT_CHLTE ;  Q7P0S3, COBT_CHRVO ;
DR   Q97JB4, COBT_CLOAB ;  B8I7A3, COBT_CLOCE ;  Q180T6, COBT_CLOD6 ;
DR   Q0TRK5, COBT_CLOP1 ;  Q8XLK7, COBT_CLOPE ;  Q891S7, COBT_CLOTE ;
DR   A3DF00, COBT_CLOTH ;  Q8FNQ2, COBT_COREF ;  A4QFR5, COBT_CORGB ;
DR   Q8NNJ8, COBT_CORGL ;  Q0K7H7, COBT_CUPNH ;  B3R647, COBT_CUPTR ;
DR   Q47JS4, COBT_DECAR ;  A5FRG9, COBT_DEHSB ;  Q3ZX54, COBT_DEHSC ;
DR   Q9RYR8, COBT_DEIRA ;  B1I4H2, COBT_DESAP ;  Q30US7, COBT_DESDG ;
DR   C4XMZ1, COBT_DESMR ;  Q6ALU4, COBT_DESPS ;  A4J829, COBT_DESRM ;
DR   Q725Z4, COBT_DESVH ;  A1V9L9, COBT_DESVV ;  A7ZNF5, COBT_ECO24 ;
DR   B7UT20, COBT_ECO27 ;  B7MDB7, COBT_ECO45 ;  B7L916, COBT_ECO55 ;
DR   Q8X8V0, COBT_ECO57 ;  B5YSS0, COBT_ECO5E ;  B7NR83, COBT_ECO7I ;
DR   B7MWP8, COBT_ECO81 ;  B7M3C7, COBT_ECO8A ;  C4ZQQ4, COBT_ECOBW ;
DR   B1X6S9, COBT_ECODH ;  A8A1K5, COBT_ECOHS ;  A1ACI8, COBT_ECOK1 ;
DR   Q0TGE1, COBT_ECOL5 ;  Q8FGA5, COBT_ECOL6 ;  B1IZQ9, COBT_ECOLC ;
DR   P36562, COBT_ECOLI ;  B7NC25, COBT_ECOLU ;  B6I828, COBT_ECOSE ;
DR   B1LPV7, COBT_ECOSM ;  Q1RAB7, COBT_ECOUT ;  Q8RF14, COBT_FUSNN ;
DR   B5EEL9, COBT_GEOBB ;  Q39YG4, COBT_GEOMG ;  B9LZU2, COBT_GEOSF ;
DR   Q748J3, COBT_GEOSL ;  C6E7Q4, COBT_GEOSM ;  A5G962, COBT_GEOUR ;
DR   A9B732, COBT_HERA2 ;  A6SWY0, COBT_JANMA ;  Q28M40, COBT_JANSC ;
DR   Q04PD9, COBT_LEPBJ ;  Q055Y6, COBT_LEPBL ;  Q72M35, COBT_LEPIC ;
DR   Q8EYK9, COBT_LEPIN ;  Q9X7F4, COBT_METC4 ;  B8ERB9, COBT_METSB ;
DR   A0QEZ9, COBT_MYCA1 ;  P63842, COBT_MYCBO ;  A1KKP9, COBT_MYCBP ;
DR   C1AQC2, COBT_MYCBT ;  B8ZQK8, COBT_MYCLB ;  O32953, COBT_MYCLE ;
DR   B2HGX6, COBT_MYCMM ;  Q73YK7, COBT_MYCPA ;  A5U4N5, COBT_MYCTA ;
DR   P63841, COBT_MYCTU ;  A0PTP2, COBT_MYCUA ;  Q2GBJ7, COBT_NOVAD ;
DR   A6X1H0, COBT_OCHA4 ;  A6LIW6, COBT_PARD8 ;  Q3A798, COBT_PELCD ;
DR   B4SH92, COBT_PELPB ;  Q7N2U4, COBT_PHOLL ;  Q6LSY3, COBT_PHOPR ;
DR   B2RIR0, COBT_PORG3 ;  Q7MWC6, COBT_PORGI ;  B4S893, COBT_PROA2 ;
DR   A4SEC8, COBT_PROVI ;  Q48FJ9, COBT_PSE14 ;  B7UWH1, COBT_PSEA8 ;
DR   Q02JC0, COBT_PSEAB ;  Q9I465, COBT_PSEAE ;  Q1IDJ7, COBT_PSEE4 ;
DR   Q4K8C1, COBT_PSEF5 ;  C3K0Y8, COBT_PSEFS ;  Q3IK32, COBT_PSEHT ;
DR   A4XT55, COBT_PSEMY ;  A5W7Q4, COBT_PSEP1 ;  Q3KFR5, COBT_PSEPF ;
DR   B0KT67, COBT_PSEPG ;  Q88M95, COBT_PSEPK ;  B1J1N8, COBT_PSEPW ;
DR   Q885W6, COBT_PSESM ;  Q4ZQ66, COBT_PSEU2 ;  Q8XWS3, COBT_RALSO ;
DR   B3PQS3, COBT_RHIE6 ;  Q2K7G6, COBT_RHIEC ;  Q1MFK4, COBT_RHIL3 ;
DR   Q98KN9, COBT_RHILO ;  B5ZSC4, COBT_RHILW ;  Q92P98, COBT_RHIME ;
DR   C3MDH9, COBT_RHISN ;  P0CY58, COBT_RHOCA ;  D5AV20, COBT_RHOCB ;
DR   A3PIN5, COBT_RHOS1 ;  Q3J3P6, COBT_RHOS4 ;  A4WRE3, COBT_RHOS5 ;
DR   B9KQ95, COBT_RHOSK ;  A7NH25, COBT_ROSCS ;  Q169A0, COBT_ROSDO ;
DR   A5UQS8, COBT_ROSS1 ;  B5EWY2, COBT_SALA4 ;  A9MLS8, COBT_SALAR ;
DR   B5FLY4, COBT_SALDC ;  B5QYX3, COBT_SALEP ;  B5RBK6, COBT_SALG2 ;
DR   B4T8W8, COBT_SALHS ;  B4SWC5, COBT_SALNS ;  Q5PDU9, COBT_SALPA ;
DR   A9MTA4, COBT_SALPB ;  C0Q1R0, COBT_SALPC ;  B5BG60, COBT_SALPK ;
DR   B4TZP5, COBT_SALSV ;  Q8Z5N9, COBT_SALTI ;  A4XAM8, COBT_SALTO ;
DR   Q05603, COBT_SALTY ;  A1S3L3, COBT_SHEAM ;  B8E4M8, COBT_SHEB2 ;
DR   A3D7X8, COBT_SHEB5 ;  A6WJZ1, COBT_SHEB8 ;  A9L3D8, COBT_SHEB9 ;
DR   Q086T6, COBT_SHEFN ;  B0TT63, COBT_SHEHH ;  A3QAT8, COBT_SHELP ;
DR   Q8EI18, COBT_SHEON ;  A4Y9P3, COBT_SHEPC ;  B8CJ37, COBT_SHEPW ;
DR   A0L0D3, COBT_SHESA ;  A8FZR5, COBT_SHESH ;  Q0HLZ5, COBT_SHESM ;
DR   Q0HRU1, COBT_SHESR ;  A1RGP1, COBT_SHESW ;  B2TWR0, COBT_SHIB3 ;
DR   Q32ED0, COBT_SHIDS ;  Q0T3C4, COBT_SHIF8 ;  Q83R14, COBT_SHIFL ;
DR   Q3Z0K4, COBT_SHISS ;  Q5LTJ1, COBT_SILPO ;  Q1GJ55, COBT_SILST ;
DR   A6U9W4, COBT_SINMW ;  Q82AM7, COBT_STRAW ;  Q9S2R1, COBT_STRCO ;
DR   A0LF21, COBT_SYNFM ;  Q7SIC7, COBT_THET8 ;  C5CKN8, COBT_VARPS ;
DR   Q9KSL9, COBT_VIBCH ;  A7MVW6, COBT_VIBHB ;  Q87Q46, COBT_VIBPA ;
DR   B7VPD7, COBT_VIBSL ;  Q8D921, COBT_VIBVU ;  Q7MLF3, COBT_VIBVY ;
DR   Q8PHR3, COBT_XANAC ;  Q3BQB7, COBT_XANC5 ;  Q4UXQ4, COBT_XANC8 ;
DR   B0RPU9, COBT_XANCB ;  Q8P6B1, COBT_XANCP ;  Q2P631, COBT_XANOM ;
DR   B2SJ67, COBT_XANOP ;  A1JTP8, COBT_YERE8 ;  P29935, COBU_PSEDE ;
//
ID   2.4.2.22
DE   Xanthine phosphoribosyltransferase.
AN   Xan phosphoribosyltransferase.
AN   Xanthine-guanine phosphoribosyltransferase.
AN   Xanthosine 5'-phosphate pyrophosphorylase.
AN   Xanthylate pyrophosphorylase.
AN   Xanthylic pyrophosphorylase.
AN   XMP pyrophosphorylase.
CA   XMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine.
PR   PROSITE; PDOC00096;
DR   Q4QMP2, XGPT1_HAEI8;  Q4QMM6, XGPT2_HAEI8;  A3MYX7, XGPT_ACTP2 ;
DR   A6VKR2, XGPT_ACTSZ ;  A0KNR2, XGPT_AERHH ;  A4SJF2, XGPT_AERS4 ;
DR   Q8UEM6, XGPT_AGRT5 ;  B6EIE9, XGPT_ALISL ;  Q89IM4, XGPT_BRAJA ;
DR   Q2YQ27, XGPT_BRUA2 ;  A9MB59, XGPT_BRUC2 ;  Q8YH64, XGPT_BRUME ;
DR   B0CGJ6, XGPT_BRUSI ;  Q8G0P3, XGPT_BRUSU ;  P57339, XGPT_BUCAI ;
DR   Q8K9R8, XGPT_BUCAP ;  Q89AN2, XGPT_BUCBP ;  Q1QVR0, XGPT_CHRSD ;
DR   A8AKQ0, XGPT_CITK8 ;  Q311U1, XGPT_DESDG ;  Q6AQG4, XGPT_DESPS ;
DR   Q72D63, XGPT_DESVH ;  A1VES8, XGPT_DESVV ;  A7ZHZ7, XGPT_ECO24 ;
DR   B7UJC6, XGPT_ECO27 ;  B7MC88, XGPT_ECO45 ;  B7L3Z0, XGPT_ECO55 ;
DR   P0A9M6, XGPT_ECO57 ;  B5Z1I2, XGPT_ECO5E ;  B7NK87, XGPT_ECO7I ;
DR   B7MQ74, XGPT_ECO81 ;  B7M267, XGPT_ECO8A ;  C4ZT95, XGPT_ECOBW ;
DR   B1XDY1, XGPT_ECODH ;  A7ZWK1, XGPT_ECOHS ;  A1A7U9, XGPT_ECOK1 ;
DR   Q0TL78, XGPT_ECOL5 ;  Q8FKM7, XGPT_ECOL6 ;  B1J0Z6, XGPT_ECOLC ;
DR   P0A9M5, XGPT_ECOLI ;  B7N8G9, XGPT_ECOLU ;  B6I018, XGPT_ECOSE ;
DR   B1LHT4, XGPT_ECOSM ;  Q1RFT3, XGPT_ECOUT ;  C5B9M4, XGPT_EDWI9 ;
DR   A4W6X0, XGPT_ENT38 ;  A7MEN2, XGPT_ENTS8 ;  Q6D1I0, XGPT_ERWCT ;
DR   B2VHN3, XGPT_ERWT9 ;  B7LNG2, XGPT_ESCF3 ;  Q5FUI1, XGPT_GLUOX ;
DR   Q7VKP2, XGPT_HAEDU ;  P43859, XGPT_HAEIN ;  Q0I1C0, XGPT_HAES1 ;
DR   B0UWV5, XGPT_HAES2 ;  Q5QW45, XGPT_IDILO ;  Q28PG8, XGPT_JANSC ;
DR   B5Y1E0, XGPT_KLEP3 ;  A6T532, XGPT_KLEP7 ;  Q65QN6, XGPT_MANSM ;
DR   Q11IP4, XGPT_MESSB ;  Q1QK75, XGPT_NITHX ;  Q3SQJ9, XGPT_NITWN ;
DR   A6X0U5, XGPT_OCHA4 ;  Q9CL73, XGPT_PASMU ;  C6DCY0, XGPT_PECCP ;
DR   Q7N7B4, XGPT_PHOLL ;  Q6LTX6, XGPT_PHOPR ;  B4EUU7, XGPT_PROMH ;
DR   Q2K9D7, XGPT_RHIEC ;  Q1MHW9, XGPT_RHIL3 ;  Q98NH3, XGPT_RHILO ;
DR   Q92PU1, XGPT_RHIME ;  Q2IV51, XGPT_RHOP2 ;  Q6N7S7, XGPT_RHOPA ;
DR   Q212I9, XGPT_RHOPB ;  Q138L1, XGPT_RHOPS ;  A3PIG2, XGPT_RHOS1 ;
DR   Q3J3Y6, XGPT_RHOS4 ;  A4WRD6, XGPT_RHOS5 ;  Q163Y8, XGPT_ROSDO ;
DR   B5EWK0, XGPT_SALA4 ;  A9MNR9, XGPT_SALAR ;  Q57ST7, XGPT_SALCH ;
DR   B5FJW9, XGPT_SALDC ;  B5R4S1, XGPT_SALEP ;  B5R5R4, XGPT_SALG2 ;
DR   B4T7Q0, XGPT_SALHS ;  B4SVV9, XGPT_SALNS ;  Q5PF80, XGPT_SALPA ;
DR   A9MY09, XGPT_SALPB ;  C0Q6T6, XGPT_SALPC ;  B5BDQ2, XGPT_SALPK ;
DR   B4TZ85, XGPT_SALSV ;  P0A278, XGPT_SALTI ;  P0A277, XGPT_SALTY ;
DR   A8GAD0, XGPT_SERP5 ;  B2U3S9, XGPT_SHIB3 ;  Q325P8, XGPT_SHIBS ;
DR   Q32J21, XGPT_SHIDS ;  Q0T7Q9, XGPT_SHIF8 ;  P0A9M7, XGPT_SHIFL ;
DR   Q3Z599, XGPT_SHISS ;  Q5LRI5, XGPT_SILPO ;  Q1GHI7, XGPT_SILST ;
DR   A6U9A2, XGPT_SINMW ;  Q2NVF2, XGPT_SODGM ;  A5F5Y8, XGPT_VIBC3 ;
DR   Q9KPT5, XGPT_VIBCH ;  C3LQ49, XGPT_VIBCM ;  Q5E6W3, XGPT_VIBF1 ;
DR   A7MWU9, XGPT_VIBHB ;  Q87RV3, XGPT_VIBPA ;  B7VJB5, XGPT_VIBSL ;
DR   Q8DF90, XGPT_VIBVU ;  Q7MN62, XGPT_VIBVY ;  A1JNY0, XGPT_YERE8 ;
DR   A7FLI5, XGPT_YERP3 ;  Q1C4E3, XGPT_YERPA ;  B2K658, XGPT_YERPB ;
DR   Q8ZC05, XGPT_YERPE ;  A9R2X4, XGPT_YERPG ;  Q1CLD0, XGPT_YERPN ;
DR   A4TPK4, XGPT_YERPP ;  Q66DZ2, XGPT_YERPS ;  B1JIH6, XGPT_YERPY ;
DR   A7FPI7, XPT1_CLOB1 ;  A5HYL0, XPT1_CLOBH ;  A7GA73, XPT1_CLOBL ;
DR   Q0TUB1, XPT1_CLOP1 ;  Q8XNJ8, XPT1_CLOPE ;  Q0SW58, XPT1_CLOPS ;
DR   A7FT29, XPT2_CLOB1 ;  A5I0Y0, XPT2_CLOBH ;  A7GCI1, XPT2_CLOBL ;
DR   Q0TQZ9, XPT2_CLOP1 ;  Q8XKV0, XPT2_CLOPE ;  Q0STE8, XPT2_CLOPS ;
DR   Q6F7W2, XPT_ACIAD  ;  B7GW49, XPT_ACIB3  ;  B7I9E1, XPT_ACIB5  ;
DR   B2HZ61, XPT_ACIBC  ;  A3M938, XPT_ACIBT  ;  A6TTD6, XPT_ALKMQ  ;
DR   C1DJZ2, XPT_AZOVD  ;  A7Z5W2, XPT_BACA2  ;  C3P5T8, XPT_BACAA  ;
DR   C3L8M1, XPT_BACAC  ;  A0RC17, XPT_BACAH  ;  Q81SQ5, XPT_BACAN  ;
DR   B7JHT4, XPT_BACC0  ;  Q73AS5, XPT_BACC1  ;  B7IPE6, XPT_BACC2  ;
DR   C1ENK3, XPT_BACC3  ;  B7HHX2, XPT_BACC4  ;  B7HL82, XPT_BACC7  ;
DR   A7GNB6, XPT_BACCN  ;  B9IVT8, XPT_BACCQ  ;  Q81FL2, XPT_BACCR  ;
DR   Q63DG7, XPT_BACCZ  ;  Q5LEQ1, XPT_BACFN  ;  Q64VN7, XPT_BACFR  ;
DR   Q9KCQ5, XPT_BACHD  ;  Q6HKZ0, XPT_BACHK  ;  Q65I86, XPT_BACLD  ;
DR   A8FEE7, XPT_BACP2  ;  Q5WI27, XPT_BACSK  ;  P42085, XPT_BACSU  ;
DR   Q8AAN7, XPT_BACTN  ;  A6L3C5, XPT_BACV8  ;  A9VMH5, XPT_BACWK  ;
DR   B8DUR4, XPT_BIFA0  ;  A1A190, XPT_BIFAA  ;  B3DSF5, XPT_BIFLD  ;
DR   Q8G5W1, XPT_BIFLO  ;  B7GSB6, XPT_BIFLS  ;  C0ZJ16, XPT_BREBN  ;
DR   A9WA88, XPT_CHLAA  ;  B9LCT9, XPT_CHLSY  ;  Q97KP4, XPT_CLOAB  ;
DR   A6LW55, XPT_CLOB8  ;  B2V327, XPT_CLOBA  ;  B2TL11, XPT_CLOBB  ;
DR   B8I1G1, XPT_CLOCE  ;  Q185K4, XPT_CLOD6  ;  A0Q2P2, XPT_CLONN  ;
DR   A9KTA4, XPT_CLOPH  ;  Q891I6, XPT_CLOTE  ;  C1CZX7, XPT_DEIDV  ;
DR   Q1J141, XPT_DEIGD  ;  Q9RTY2, XPT_DEIRA  ;  A4J6I7, XPT_DESRM  ;
DR   Q831Y0, XPT_ENTFA  ;  C4ZA66, XPT_EUBR3  ;  B1YHS1, XPT_EXIS2  ;
DR   C4L0T7, XPT_EXISA  ;  B0S259, XPT_FINM2  ;  A4IN63, XPT_GEOTN  ;
DR   B0TCJ8, XPT_HELMI  ;  Q5FMD9, XPT_LACAC  ;  Q03Q10, XPT_LACBA  ;
DR   Q03A64, XPT_LACC3  ;  B3WDB0, XPT_LACCB  ;  Q1GBU9, XPT_LACDA  ;
DR   Q04CA6, XPT_LACDB  ;  B2GDT2, XPT_LACF3  ;  Q046I4, XPT_LACGA  ;
DR   A8YXG4, XPT_LACH4  ;  Q74LF9, XPT_LACJO  ;  Q9CGF0, XPT_LACLA  ;
DR   A2RKX0, XPT_LACLM  ;  Q02Z29, XPT_LACLS  ;  Q88XQ4, XPT_LACPL  ;
DR   A5VLG9, XPT_LACRD  ;  B2G8U2, XPT_LACRJ  ;  Q1WSL3, XPT_LACS1  ;
DR   Q38VB9, XPT_LACSS  ;  C1DBA1, XPT_LARHH  ;  Q03UJ4, XPT_LEUMM  ;
DR   Q92AC4, XPT_LISIN  ;  C1KWI4, XPT_LISMC  ;  Q71YD1, XPT_LISMF  ;
DR   Q8Y617, XPT_LISMO  ;  A0AJZ0, XPT_LISW6  ;  B9E8Y3, XPT_MACCJ  ;
DR   Q2RKK1, XPT_MOOTA  ;  Q8CUP6, XPT_OCEIH  ;  Q04GD7, XPT_OENOB  ;
DR   A6LC43, XPT_PARD8  ;  Q03EG0, XPT_PEDPA  ;  B2RH69, XPT_PORG3  ;
DR   Q7MT44, XPT_PORGI  ;  Q48QC3, XPT_PSE14  ;  A6VEA3, XPT_PSEA7  ;
DR   B7V5I9, XPT_PSEA8  ;  Q02E64, XPT_PSEAB  ;  Q9HTQ6, XPT_PSEAE  ;
DR   Q1I2W1, XPT_PSEE4  ;  Q4K3U3, XPT_PSEF5  ;  C3K452, XPT_PSEFS  ;
DR   A4XNV9, XPT_PSEMY  ;  A5WAY3, XPT_PSEP1  ;  Q3K4P7, XPT_PSEPF  ;
DR   B0KQ69, XPT_PSEPG  ;  Q88CB6, XPT_PSEPK  ;  Q88BA5, XPT_PSESM  ;
DR   Q500M2, XPT_PSEU2  ;  A4VGU2, XPT_PSEU5  ;  A7WY89, XPT_STAA1  ;
DR   A6TYN9, XPT_STAA2  ;  Q2FJM8, XPT_STAA3  ;  Q2G0Y9, XPT_STAA8  ;
DR   A5IPW7, XPT_STAA9  ;  Q2YVL8, XPT_STAAB  ;  Q5HIQ9, XPT_STAAC  ;
DR   A6QE68, XPT_STAAE  ;  Q99WJ1, XPT_STAAM  ;  Q7A7I5, XPT_STAAN  ;
DR   Q6GJQ9, XPT_STAAR  ;  Q6GC84, XPT_STAAS  ;  A8Z0Q8, XPT_STAAT  ;
DR   Q7A1T6, XPT_STAAW  ;  B9DM01, XPT_STACT  ;  Q5HRX4, XPT_STAEQ  ;
DR   Q8CQR0, XPT_STAES  ;  Q4L383, XPT_STAHJ  ;  Q49UU6, XPT_STAS1  ;
DR   Q3K111, XPT_STRA1  ;  Q8E5B5, XPT_STRA3  ;  Q8DZL5, XPT_STRA5  ;
DR   C0MBC1, XPT_STRE4  ;  A8AXD5, XPT_STRGC  ;  Q9ZEE3, XPT_STRMT  ;
DR   Q99ZQ0, XPT_STRP1  ;  Q04IV9, XPT_STRP2  ;  P0DH48, XPT_STRP3  ;
DR   B5E1V8, XPT_STRP4  ;  Q5XC74, XPT_STRP6  ;  C1C9B2, XPT_STRP7  ;
DR   Q7CN84, XPT_STRP8  ;  Q1JBS4, XPT_STRPB  ;  Q1JLQ7, XPT_STRPC  ;
DR   Q1JGV7, XPT_STRPD  ;  Q1J6M6, XPT_STRPF  ;  A2REI4, XPT_STRPG  ;
DR   B1I857, XPT_STRPI  ;  B8ZN87, XPT_STRPJ  ;  Q48TL5, XPT_STRPM  ;
DR   Q97P00, XPT_STRPN  ;  P0DH49, XPT_STRPQ  ;  B2ISU6, XPT_STRPS  ;
DR   B5XLI3, XPT_STRPZ  ;  Q8DNL1, XPT_STRR6  ;  C0MF03, XPT_STRS7  ;
DR   A3CMY9, XPT_STRSV  ;  Q9AGS1, XPT_STRTR  ;  B9DS40, XPT_STRU0  ;
DR   C1CG72, XPT_STRZJ  ;  C1CMF7, XPT_STRZP  ;  C1CT78, XPT_STRZT  ;
//
ID   2.4.2.23
DE   Deoxyuridine phosphorylase.
CA   2'-deoxyuridine + phosphate = uracil + 2-deoxy-alpha-D-ribose
CA   1-phosphate.
//
ID   2.4.2.24
DE   1,4-beta-D-xylan synthase.
CA   UDP-D-xylose + ((1->4)-beta-D-xylan)(n) = UDP + ((1->4)-beta-D-
CA   xylan)(n+1).
CC   -!- Formerly EC 2.4.1.72.
//
ID   2.4.2.25
DE   Flavone apiosyltransferase.
CA   UDP-apiose + 5,7,4'-trihydroxyflavone 7-O-beta-D-glucoside = UDP +
CA   5,7,4'-trihydroxyflavone 7-O-(beta-D-apiosyl-(1->2)-beta-D-glucoside).
CC   -!- 7-O-beta-D-glucosides of a number of flavonoids and of 4-substituted
CC       phenols can act as acceptors.
//
ID   2.4.2.26
DE   Protein xylosyltransferase.
AN   UDP-D-xylose:core protein beta-D-xylosyltransferase.
AN   UDP-D-xylose:core protein xylosyltransferase.
AN   UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase.
AN   UDP-xylose-core protein beta-D-xylosyltransferase.
AN   Uridine diphosphoxylose-core protein beta-xylosyltransferase.
AN   Uridine diphosphoxylose-protein xylosyltransferase.
CA   Transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine
CA   hydroxy group of an acceptor protein substrate.
CC   -!- Involved in the biosynthesis of the linkage region of
CC       glycosaminoglycan chains as part of proteoglycan biosynthesis
CC       (chondroitin, dermatan and heparan sulfates).
DR   Q5QQ56, XYLT1_CANFA;  Q86Y38, XYLT1_HUMAN;  Q811B1, XYLT1_MOUSE;
DR   Q5QQ57, XYLT1_PANTR;  Q9EPI1, XYLT1_RAT  ;  Q5QQ49, XYLT2_BOVIN;
DR   Q5QQ50, XYLT2_CANFA;  Q9H1B5, XYLT2_HUMAN;  Q9EPL0, XYLT2_MOUSE;
DR   Q5QQ51, XYLT2_PANTR;  Q9EPI0, XYLT2_RAT  ;  Q5QQ52, XYLT_CAEBR ;
DR   Q965Q8, XYLT_CAEEL ;  Q5QQ55, XYLT_CIOIN ;  Q5QQ54, XYLT_CIOSA ;
DR   Q7KVA1, XYLT_DROME ;  Q5QQ53, XYLT_DROPS ;
//
ID   2.4.2.27
DE   dTDP-dihydrostreptose--streptidine-6-phosphate
DE   dihydrostreptosyltransferase.
CA   dTDP-L-dihydrostreptose + streptidine 6-phosphate = dTDP + O-(1->4)-
CA   alpha-L-dihydrostreptosyl-streptidine 6-phosphate.
DR   P09399, STRH_STRGR ;
//
ID   2.4.2.28
DE   S-methyl-5'-thioadenosine phosphorylase.
AN   5'-deoxy-5'-methylthioadenosine phosphorylase.
AN   5'-methylthioadenosine nucleosidase.
AN   5'-methylthioadenosine phosphorylase.
AN   MeSAdo phosphorylase.
AN   MeSAdo/Ado phosphorylase.
AN   Methylthioadenosine nucleoside phosphorylase.
AN   Methylthioadenosine phosphorylase.
AN   MTA phosphorylase.
AN   MTAPase.
CA   S-methyl-5'-thioadenosine + phosphate = adenine + S-methyl-5-thio-alpha-
CA   D-ribose 1-phosphate.
CC   -!- Also acts on 5'-deoxyadenosine and other analogs having 5'-deoxy
CC       groups.
PR   PROSITE; PDOC00946;
PR   PROSITE; PDOC00954;
DR   Q09438, MTAP_CAEEL ;  Q9V813, MTAP_DROME ;  Q13126, MTAP_HUMAN ;
DR   Q9CQ65, MTAP_MOUSE ;  P50389, MTAP_SULSO ;  Q72LZ4, MTNP_LEPIC ;
DR   Q8CXR2, MTNP_LEPIN ;  Q9HZK1, MTNP_PSEAE ;  Q87ZC3, MTNP_PSESM ;
DR   Q9PAZ2, MTNP_XYLFA ;  Q87BR7, MTNP_XYLFT ;
//
ID   2.4.2.29
DE   tRNA-guanine transglycosylase.
AN   Guanine insertion enzyme.
AN   Q-insertase.
AN   Queuine tRNA-ribosyltransferase.
AN   TGT.
AN   tRNA guanine transglycosidase.
AN   tRNA transglycosylase.
CA   (1) [tRNA]-guanine + queuine = [tRNA]-queuine + guanine.
CA   (2) [tRNA]-guanine + 7-aminomethyl-7-carbaguanine = [tRNA]-7-aminomethyl-
CA   7-carbaguanine + guanine.
CC   -!- In eukaryotes, queuine is incorporated into tRNA directly via a base-
CC       exchange reaction (replacing guanine) whereas in eubacteria,
CC       the queuine precursor preQ(1) is incorporated and ultimately modified
CC       to queuine.
CC   -!- In eubacteria, preQ(0) can also be incorporated into undermodified
CC       tRNA(Tyr) and tRNA(Asn) containing normal guanine instead of queuine
CC       in the first position of the anticodon.
CC   -!- Acts after EC 1.7.1.13 in the queuine-biosynthesis pathway.
DR   Q16RF5, QTRD1_AEDAE;  Q7Q727, QTRD1_ANOGA;  A8WJ41, QTRD1_CAEBR;
DR   Q9NEU3, QTRD1_CAEEL;  Q5ZM96, QTRD1_CHICK;  B0WAN0, QTRD1_CULQU;
DR   Q7ZVJ6, QTRD1_DANRE;  B3MA91, QTRD1_DROAN;  B3NCH1, QTRD1_DROER;
DR   B4IXD3, QTRD1_DROGR;  Q9VSZ6, QTRD1_DROME;  B4KXI8, QTRD1_DROMO;
DR   B4H1X9, QTRD1_DROPE;  Q29EE9, QTRD1_DROPS;  B4HL48, QTRD1_DROSE;
DR   B4LFW2, QTRD1_DROVI;  B4N549, QTRD1_DROWI;  B4PEV9, QTRD1_DROYA;
DR   Q9H974, QTRD1_HUMAN;  B7Q5K1, QTRD1_IXOSC;  B8ZXI1, QTRD1_MOUSE;
DR   Q5R998, QTRD1_PONAB;  B3RNT0, QTRD1_TRIAD;  Q6DF96, QTRD1_XENLA;
DR   Q28DX0, QTRD1_XENTR;  A1TVN0, TGT_ACIAC  ;  Q6FEJ4, TGT_ACIAD  ;
DR   B7GWL4, TGT_ACIB3  ;  B7I976, TGT_ACIB5  ;  B2HYN7, TGT_ACIBC  ;
DR   Q1IVF1, TGT_ACIBL  ;  B0VRA8, TGT_ACIBS  ;  A3M8S3, TGT_ACIBT  ;
DR   B0V625, TGT_ACIBY  ;  B9MGI1, TGT_ACIET  ;  B7J4R9, TGT_ACIF2  ;
DR   B5EK08, TGT_ACIF5  ;  A1WCK2, TGT_ACISJ  ;  A3N087, TGT_ACTP2  ;
DR   B3GXF8, TGT_ACTP7  ;  B0BP03, TGT_ACTPJ  ;  A6VN75, TGT_ACTSZ  ;
DR   A0KJ20, TGT_AERHH  ;  A4SP26, TGT_AERS4  ;  Q8UES8, TGT_AGRT5  ;
DR   B6EK65, TGT_ALISL  ;  B7GFN1, TGT_ANOFW  ;  O67331, TGT_AQUAE  ;
DR   A8ERD1, TGT_ARCB4  ;  O28787, TGT_ARCFU  ;  Q5P720, TGT_AROAE  ;
DR   A1K3W9, TGT_AZOSB  ;  C1DE76, TGT_AZOVD  ;  A7Z766, TGT_BACA2  ;
DR   C3P9A4, TGT_BACAA  ;  C3L6U6, TGT_BACAC  ;  A0RJ24, TGT_BACAH  ;
DR   Q81LH2, TGT_BACAN  ;  B7JQ03, TGT_BACC0  ;  Q730B4, TGT_BACC1  ;
DR   B7IIS9, TGT_BACC2  ;  C1ESW1, TGT_BACC3  ;  B7HE51, TGT_BACC4  ;
DR   B7HQH6, TGT_BACC7  ;  A7GT99, TGT_BACCN  ;  B9IYZ1, TGT_BACCQ  ;
DR   Q817W6, TGT_BACCR  ;  Q634C7, TGT_BACCZ  ;  Q9KDI5, TGT_BACHD  ;
DR   Q6HDA9, TGT_BACHK  ;  Q65GP9, TGT_BACLD  ;  A8FFQ9, TGT_BACP2  ;
DR   Q5WHR2, TGT_BACSK  ;  O32053, TGT_BACSU  ;  A9VIP3, TGT_BACWK  ;
DR   Q1LSP0, TGT_BAUCH  ;  Q7VQB1, TGT_BLOFL  ;  Q493H3, TGT_BLOPB  ;
DR   O51749, TGT_BORBU  ;  B7J0Q4, TGT_BORBZ  ;  B5RN03, TGT_BORDL  ;
DR   Q65ZW4, TGT_BORGA  ;  B2S1F3, TGT_BORHD  ;  B5RQE7, TGT_BORRA  ;
DR   A1R0N4, TGT_BORT9  ;  C0R0X6, TGT_BRAHW  ;  Q8YHB2, TGT_BRUME  ;
DR   Q8G0K1, TGT_BRUSU  ;  B8D8T4, TGT_BUCA5  ;  P57233, TGT_BUCAI  ;
DR   Q8KA09, TGT_BUCAP  ;  B8D738, TGT_BUCAT  ;  A8X0P0, TGT_CAEBR  ;
DR   Q23623, TGT_CAEEL  ;  A7ZD89, TGT_CAMC1  ;  A7GYD5, TGT_CAMC5  ;
DR   A0RPL5, TGT_CAMFF  ;  A7I2I6, TGT_CAMHC  ;  A8FM59, TGT_CAMJ8  ;
DR   A7H331, TGT_CAMJD  ;  Q9PNT0, TGT_CAMJE  ;  A1VZZ8, TGT_CAMJJ  ;
DR   Q5HUF2, TGT_CAMJR  ;  B9KFT3, TGT_CAMLR  ;  Q9A7Y1, TGT_CAUCR  ;
DR   Q5L5T1, TGT_CHLAB  ;  Q822U8, TGT_CHLCV  ;  Q254U7, TGT_CHLFF  ;
DR   Q9PKK0, TGT_CHLMU  ;  Q9Z8W5, TGT_CHLPN  ;  B0B9U3, TGT_CHLT2  ;
DR   Q3KMG9, TGT_CHLTA  ;  B0BBH3, TGT_CHLTB  ;  O84196, TGT_CHLTR  ;
DR   Q1QTM9, TGT_CHRSD  ;  Q7NYC7, TGT_CHRVO  ;  A8AK48, TGT_CITK8  ;
DR   Q97GT3, TGT_CLOAB  ;  A7FY17, TGT_CLOB1  ;  C3KTD0, TGT_CLOB6  ;
DR   A5I6E9, TGT_CLOBH  ;  C1FKF9, TGT_CLOBJ  ;  B1IMF1, TGT_CLOBK  ;
DR   A7GHT6, TGT_CLOBL  ;  B1L0B0, TGT_CLOBM  ;  B8I6M0, TGT_CLOCE  ;
DR   B9E5Q6, TGT_CLOK1  ;  A5N204, TGT_CLOK5  ;  Q0TP15, TGT_CLOP1  ;
DR   Q8XJ16, TGT_CLOPE  ;  A9KHU4, TGT_CLOPH  ;  Q0SRN5, TGT_CLOPS  ;
DR   Q892A0, TGT_CLOTE  ;  A3DE13, TGT_CLOTH  ;  Q0K733, TGT_CUPNH  ;
DR   Q46XG4, TGT_CUPPJ  ;  B3R6J4, TGT_CUPTR  ;  B8HX02, TGT_CYAP4  ;
DR   Q7SYK1, TGT_DANRE  ;  Q47AX3, TGT_DECAR  ;  Q3ZAE2, TGT_DEHE1  ;
DR   A5FSU3, TGT_DEHSB  ;  Q3ZWC1, TGT_DEHSC  ;  Q9RRB5, TGT_DEIRA  ;
DR   A9BRD7, TGT_DELAS  ;  C0QKY2, TGT_DESAH  ;  B1I4K8, TGT_DESAP  ;
DR   Q30XF7, TGT_DESDG  ;  B8FQV2, TGT_DESHD  ;  C4XSI9, TGT_DESMR  ;
DR   A8ZRX7, TGT_DESOH  ;  A4J541, TGT_DESRM  ;  Q72E53, TGT_DESVH  ;
DR   A1VFP3, TGT_DESVV  ;  A5EW66, TGT_DICNV  ;  B5YFK5, TGT_DICT6  ;
DR   B8E2N5, TGT_DICTD  ;  A8LRQ1, TGT_DINSH  ;  Q9VPY8, TGT_DROME  ;
DR   A7ZIF8, TGT_ECO24  ;  B7UJM9, TGT_ECO27  ;  B7MD64, TGT_ECO45  ;
DR   B7L639, TGT_ECO55  ;  P0A849, TGT_ECO57  ;  B5Z2W2, TGT_ECO5E  ;
DR   B7NJ96, TGT_ECO7I  ;  B7MPG7, TGT_ECO81  ;  B7M3P5, TGT_ECO8A  ;
DR   C4ZTG3, TGT_ECOBW  ;  B1XEZ4, TGT_ECODH  ;  A7ZX57, TGT_ECOHS  ;
DR   A1A876, TGT_ECOK1  ;  Q0TKN5, TGT_ECOL5  ;  P0A848, TGT_ECOL6  ;
DR   B1J043, TGT_ECOLC  ;  P0A847, TGT_ECOLI  ;  B7N8V8, TGT_ECOLU  ;
DR   B6HZK6, TGT_ECOSE  ;  B1LJF4, TGT_ECOSM  ;  Q1RFD5, TGT_ECOUT  ;
DR   C5BCF7, TGT_EDWI9  ;  A4W779, TGT_ENT38  ;  Q837E7, TGT_ENTFA  ;
DR   Q6D855, TGT_ERWCT  ;  B2VHQ1, TGT_ERWT9  ;  B7LMI1, TGT_ESCF3  ;
DR   C4Z563, TGT_EUBE2  ;  B0TYY3, TGT_FRAP2  ;  Q14HA0, TGT_FRAT1  ;
DR   A7NBL6, TGT_FRATF  ;  Q2A3Y7, TGT_FRATH  ;  B2SHD4, TGT_FRATM  ;
DR   A0Q6X1, TGT_FRATN  ;  Q0BMC7, TGT_FRATO  ;  Q5NFU8, TGT_FRATT  ;
DR   A4IYF8, TGT_FRATW  ;  Q8RDN0, TGT_FUSNN  ;  Q5KWR4, TGT_GEOKA  ;
DR   A4IRA9, TGT_GEOTN  ;  Q7NMG4, TGT_GLOVI  ;  A9HBJ2, TGT_GLUDA  ;
DR   Q0BVG4, TGT_GRABC  ;  Q7VLQ4, TGT_HAEDU  ;  Q4QNU3, TGT_HAEI8  ;
DR   A5UAP3, TGT_HAEIE  ;  A5UG47, TGT_HAEIG  ;  P44594, TGT_HAEIN  ;
DR   B8F3W0, TGT_HAEPS  ;  Q0I4R8, TGT_HAES1  ;  B8CXG0, TGT_HALOH  ;
DR   C4K8M3, TGT_HAMD5  ;  Q17YB5, TGT_HELAH  ;  Q7VHX2, TGT_HELHP  ;
DR   B6JKL0, TGT_HELP2  ;  B5ZA47, TGT_HELPG  ;  Q1CUM2, TGT_HELPH  ;
DR   Q9ZMF4, TGT_HELPJ  ;  B2USB2, TGT_HELPS  ;  O08314, TGT_HELPY  ;
DR   A9AW42, TGT_HERA2  ;  A4G1Z3, TGT_HERAR  ;  Q9BXR0, TGT_HUMAN  ;
DR   Q5QVL2, TGT_IDILO  ;  A6SUU4, TGT_JANMA  ;  Q28PC5, TGT_JANSC  ;
DR   B5Y0Y6, TGT_KLEP3  ;  A6T5D8, TGT_KLEP7  ;  Q9CJ54, TGT_LACLA  ;
DR   A2RHN5, TGT_LACLM  ;  Q032U4, TGT_LACLS  ;  Q88V05, TGT_LACPL  ;
DR   Q38YP9, TGT_LACSS  ;  C1DDA7, TGT_LARHH  ;  Q1MPU5, TGT_LAWIP  ;
DR   B0SCA8, TGT_LEPBA  ;  Q04UC6, TGT_LEPBJ  ;  Q04Z48, TGT_LEPBL  ;
DR   B0SKS9, TGT_LEPBP  ;  B1XWG6, TGT_LEPCP  ;  Q72TL3, TGT_LEPIC  ;
DR   Q8CXS3, TGT_LEPIN  ;  Q92BI4, TGT_LISIN  ;  C1KVH7, TGT_LISMC  ;
DR   Q71ZE0, TGT_LISMF  ;  B8DHL8, TGT_LISMH  ;  Q8Y700, TGT_LISMO  ;
DR   A0AIX9, TGT_LISW6  ;  B1HVA1, TGT_LYSSC  ;  B9E716, TGT_MACCJ  ;
DR   Q65S94, TGT_MANSM  ;  A1TZN7, TGT_MARAV  ;  Q1H403, TGT_METFK  ;
DR   B3DYE4, TGT_METI4  ;  A2SM97, TGT_METPP  ;  Q2RHU3, TGT_MOOTA  ;
DR   Q9JMA2, TGT_MOUSE  ;  B2A5K8, TGT_NATTJ  ;  B9L8E1, TGT_NAUPA  ;
DR   Q5F9U5, TGT_NEIG1  ;  B4RJY2, TGT_NEIG2  ;  A9M374, TGT_NEIM0  ;
DR   Q9JVA4, TGT_NEIMA  ;  Q9K096, TGT_NEIMB  ;  A1KSY1, TGT_NEIMF  ;
DR   Q0AG55, TGT_NITEC  ;  Q82VF0, TGT_NITEU  ;  Q2Y6A3, TGT_NITMU  ;
DR   A6Q3Y5, TGT_NITSB  ;  Q8YVT9, TGT_NOSS1  ;  Q2G639, TGT_NOVAD  ;
DR   Q8CXC4, TGT_OCEIH  ;  Q6MD31, TGT_PARUW  ;  P57831, TGT_PASMU  ;
DR   C6DB26, TGT_PECCP  ;  Q03ER2, TGT_PEDPA  ;  A5D3G6, TGT_PELTS  ;
DR   Q7MB01, TGT_PHOLL  ;  Q6LU69, TGT_PHOPR  ;  A1VJ15, TGT_POLNA  ;
DR   Q12GB2, TGT_POLSJ  ;  A3PAZ2, TGT_PROM0  ;  A8G2T1, TGT_PROM2  ;
DR   A2CCL1, TGT_PROM3  ;  A9BDP3, TGT_PROM4  ;  A2BUQ2, TGT_PROM5  ;
DR   Q31CR1, TGT_PROM9  ;  Q7VDR5, TGT_PROMA  ;  B4EU13, TGT_PROMH  ;
DR   Q7TUM6, TGT_PROMM  ;  Q7TUG0, TGT_PROMP  ;  A2BP70, TGT_PROMS  ;
DR   Q15WI4, TGT_PSEA6  ;  B7UVU4, TGT_PSEA8  ;  Q02RX7, TGT_PSEAB  ;
DR   Q9HXH9, TGT_PSEAE  ;  Q3ILB8, TGT_PSEHT  ;  Q88PL7, TGT_PSEPK  ;
DR   Q887B0, TGT_PSESM  ;  Q4FRI6, TGT_PSYA2  ;  Q1QA23, TGT_PSYCK  ;
DR   A1SWU0, TGT_PSYIN  ;  A5WGS6, TGT_PSYWF  ;  Q1LJ59, TGT_RALME  ;
DR   B2UC75, TGT_RALPJ  ;  Q8XVW4, TGT_RALSO  ;  Q4QR99, TGT_RAT    ;
DR   Q98M57, TGT_RHILO  ;  Q92PY4, TGT_RHIME  ;  Q7UWK9, TGT_RHOBA  ;
DR   A3PJT9, TGT_RHOS1  ;  Q3J2H4, TGT_RHOS4  ;  C3PLJ4, TGT_RICAE  ;
DR   A8GPN2, TGT_RICAH  ;  A8GUA5, TGT_RICB8  ;  Q1RH25, TGT_RICBR  ;
DR   A8EZT7, TGT_RICCK  ;  Q92GM6, TGT_RICCN  ;  Q4UN16, TGT_RICFE  ;
DR   A8F2K6, TGT_RICM5  ;  Q9ZCK8, TGT_RICPR  ;  C4K0T2, TGT_RICPU  ;
DR   B0BUZ2, TGT_RICRO  ;  A8GTF4, TGT_RICRS  ;  Q68W26, TGT_RICTY  ;
DR   A5USV3, TGT_ROSS1  ;  Q21KW1, TGT_SACD2  ;  B5EWT9, TGT_SALA4  ;
DR   A9MM57, TGT_SALAR  ;  Q57SF8, TGT_SALCH  ;  B5FKR0, TGT_SALDC  ;
DR   B5QTF4, TGT_SALEP  ;  B5R6Q7, TGT_SALG2  ;  B4T8P5, TGT_SALHS  ;
DR   B4SWP7, TGT_SALNS  ;  Q5PFT6, TGT_SALPA  ;  A9MX29, TGT_SALPB  ;
DR   C0Q7S9, TGT_SALPC  ;  B5BDC8, TGT_SALPK  ;  B4TZI0, TGT_SALSV  ;
DR   Q8Z8Y0, TGT_SALTI  ;  Q8ZRD8, TGT_SALTY  ;  O94460, TGT_SCHPO  ;
DR   A8GAM5, TGT_SERP5  ;  A1S7P2, TGT_SHEAM  ;  B8EDJ7, TGT_SHEB2  ;
DR   A3D6B1, TGT_SHEB5  ;  A6WQ52, TGT_SHEB8  ;  A9KUN0, TGT_SHEB9  ;
DR   Q12PD9, TGT_SHEDO  ;  Q07ZM2, TGT_SHEFN  ;  B0TND4, TGT_SHEHH  ;
DR   A3QFF5, TGT_SHELP  ;  Q8ECM3, TGT_SHEON  ;  A8H2K8, TGT_SHEPA  ;
DR   A4Y8C2, TGT_SHEPC  ;  B8CLC5, TGT_SHEPW  ;  A0KV50, TGT_SHESA  ;
DR   A8FXC6, TGT_SHESH  ;  Q0HKF7, TGT_SHESM  ;  Q0HWQ9, TGT_SHESR  ;
DR   A1RI67, TGT_SHESW  ;  B2U4K7, TGT_SHIB3  ;  Q325J5, TGT_SHIBS  ;
DR   Q32JG0, TGT_SHIDS  ;  Q0T7I3, TGT_SHIF8  ;  Q54177, TGT_SHIFL  ;
DR   Q3Z503, TGT_SHISS  ;  Q5LQ80, TGT_SILPO  ;  Q1GIL3, TGT_SILST  ;
DR   Q2NVA4, TGT_SODGM  ;  Q029K6, TGT_SOLUE  ;  A9FI06, TGT_SORC5  ;
DR   Q1GR26, TGT_SPHAL  ;  A7X354, TGT_STAA1  ;  A6U2A7, TGT_STAA2  ;
DR   Q2FG88, TGT_STAA3  ;  Q2FXT6, TGT_STAA8  ;  A5ITG3, TGT_STAA9  ;
DR   Q2YT91, TGT_STAAB  ;  Q5HFC4, TGT_STAAC  ;  A6QHI1, TGT_STAAE  ;
DR   P66904, TGT_STAAM  ;  P66905, TGT_STAAN  ;  Q6GG65, TGT_STAAR  ;
DR   Q6G8T0, TGT_STAAS  ;  A8Z2G7, TGT_STAAT  ;  P66906, TGT_STAAW  ;
DR   B9DNG7, TGT_STACT  ;  Q5HNR2, TGT_STAEQ  ;  Q8CML7, TGT_STAES  ;
DR   Q4L6Y4, TGT_STAHJ  ;  Q3K2Y7, TGT_STRA1  ;  Q8E6X6, TGT_STRA3  ;
DR   Q8E1F9, TGT_STRA5  ;  C0MAH5, TGT_STRE4  ;  A8AUL3, TGT_STRGC  ;
DR   B4SSS1, TGT_STRM5  ;  B2FN00, TGT_STRMK  ;  Q8DVZ3, TGT_STRMU  ;
DR   Q9A1L6, TGT_STRP1  ;  Q04IB3, TGT_STRP2  ;  P0DF86, TGT_STRP3  ;
DR   B5E2X9, TGT_STRP4  ;  Q5XE18, TGT_STRP6  ;  C1CAA6, TGT_STRP7  ;
DR   P66910, TGT_STRP8  ;  Q1JDS0, TGT_STRPB  ;  Q1JNN4, TGT_STRPC  ;
DR   Q1JIT0, TGT_STRPD  ;  Q1J8P1, TGT_STRPF  ;  A2RCC9, TGT_STRPG  ;
DR   B1I9B4, TGT_STRPI  ;  B8ZPB8, TGT_STRPJ  ;  Q48VG9, TGT_STRPM  ;
DR   P66907, TGT_STRPN  ;  P0DF87, TGT_STRPQ  ;  B2IMN3, TGT_STRPS  ;
DR   B5XJL3, TGT_STRPZ  ;  P66908, TGT_STRR6  ;  A4W2F8, TGT_STRS2  ;
DR   C0MEV8, TGT_STRS7  ;  A3CK60, TGT_STRSV  ;  A4VW51, TGT_STRSY  ;
DR   Q5LY05, TGT_STRT1  ;  Q5M2K9, TGT_STRT2  ;  Q03IQ5, TGT_STRTD  ;
DR   B9DVZ9, TGT_STRU0  ;  C1CGY8, TGT_STRZJ  ;  C1CN05, TGT_STRZP  ;
DR   C1CTW4, TGT_STRZT  ;  Q30S46, TGT_SULDN  ;  A6Q906, TGT_SULNB  ;
DR   Q67Q92, TGT_SYMTH  ;  Q8GAA6, TGT_SYNE7  ;  A0LFR2, TGT_SYNFM  ;
DR   Q7TTX7, TGT_SYNPX  ;  Q0IDF3, TGT_SYNS3  ;  Q3B088, TGT_SYNS9  ;
DR   Q3AN18, TGT_SYNSC  ;  Q55983, TGT_SYNY3  ;  B7IDU1, TGT_THEAB  ;
DR   Q8CWM7, TGT_THEEB  ;  A6LMW2, TGT_THEM4  ;  Q9X1P7, TGT_THEMA  ;
DR   B9K8N7, TGT_THENN  ;  A5IM22, TGT_THEP1  ;  B0K959, TGT_THEP3  ;
DR   B0K0M1, TGT_THEPX  ;  B1LB70, TGT_THESQ  ;  Q72H19, TGT_THET2  ;
DR   Q5SLI7, TGT_THET8  ;  Q8RAM9, TGT_THETN  ;  B5YHX4, TGT_THEYD  ;
DR   Q31FZ5, TGT_THICR  ;  Q3SH61, TGT_THIDA  ;  B8GTQ4, TGT_THISH  ;
DR   C4L7L3, TGT_TOLAT  ;  Q73QK5, TGT_TREDE  ;  A1WFH2, TGT_VEREI  ;
DR   A5CW46, TGT_VESOH  ;  A5F3H2, TGT_VIBC3  ;  Q9KTY9, TGT_VIBCH  ;
DR   C3LSZ4, TGT_VIBCM  ;  Q5E3D2, TGT_VIBF1  ;  B5F9Y3, TGT_VIBFM  ;
DR   A7MT83, TGT_VIBHB  ;  Q87S36, TGT_VIBPA  ;  B7VJR8, TGT_VIBSL  ;
DR   Q8DEY0, TGT_VIBVU  ;  Q7MNH1, TGT_VIBVY  ;  Q7M8N8, TGT_WOLSU  ;
DR   Q8PJL7, TGT_XANAC  ;  Q3BS37, TGT_XANC5  ;  Q4UVX2, TGT_XANC8  ;
DR   B0RRR1, TGT_XANCB  ;  Q8P868, TGT_XANCP  ;  Q2P2X0, TGT_XANOM  ;
DR   B2SIN8, TGT_XANOP  ;  Q5GZY3, TGT_XANOR  ;  Q4QQY7, TGT_XENLA  ;
DR   Q28HC6, TGT_XENTR  ;  B2I6T4, TGT_XYLF2  ;  Q9PGS5, TGT_XYLFA  ;
DR   B0U1P6, TGT_XYLFM  ;  Q87EW6, TGT_XYLFT  ;  A1JNT0, TGT_YERE8  ;
DR   A7FLF5, TGT_YERP3  ;  Q1C4H4, TGT_YERPA  ;  B2K6S6, TGT_YERPB  ;
DR   Q8ZC33, TGT_YERPE  ;  A9R351, TGT_YERPG  ;  Q1CLA2, TGT_YERPN  ;
DR   A4TPH6, TGT_YERPP  ;  Q66DW5, TGT_YERPS  ;  B1JIE9, TGT_YERPY  ;
DR   P28720, TGT_ZYMMO  ;
//
ID   2.4.2.30
DE   NAD(+) ADP-ribosyltransferase.
AN   ADP-ribosyltransferase (polymerizing).
AN   Poly(adenosine diphosphate ribose) polymerase.
AN   Poly(ADP-ribose) synthetase.
AN   Poly(ADP-ribose)polymerase.
CA   NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-
CA   ribosyl)(n+1)-acceptor.
CC   -!- The ADP-D-ribosyl group of NAD(+) is transferred to an acceptor
CC       carboxy group on a histone or the enzyme itself, and further ADP-
CC       ribosyl groups are transferred to the 2'-position of the terminal
CC       adenosine moiety, building up a polymer with an average chain length
CC       of 20-30 units.
PR   PROSITE; PDOC00360;
PR   PROSITE; PDOC51059;
DR   Q53GL7, PAR10_HUMAN;  Q9NR21, PAR11_HUMAN;  Q8CFF0, PAR11_MOUSE;
DR   Q9H0J9, PAR12_HUMAN;  Q8BZ20, PAR12_MOUSE;  Q460N5, PAR14_HUMAN;
DR   Q2EMV9, PAR14_MOUSE;  Q460N3, PAR15_HUMAN;  Q8N5Y8, PAR16_HUMAN;
DR   Q7TMM8, PAR16_MOUSE;  Q5U2Q4, PAR16_RAT  ;  Q9ZP54, PARP1_ARATH;
DR   P18493, PARP1_BOVIN;  P26446, PARP1_CHICK;  Q9R152, PARP1_CRIGR;
DR   P09874, PARP1_HUMAN;  Q9ZSV1, PARP1_MAIZE;  P11103, PARP1_MOUSE;
DR   Q08824, PARP1_ONCMA;  Q7EYV7, PARP1_ORYSJ;  P27008, PARP1_RAT  ;
DR   P31669, PARP1_XENLA;  Q11207, PARP2_ARATH;  Q9UGN5, PARP2_HUMAN;
DR   O50017, PARP2_MAIZE;  O88554, PARP2_MOUSE;  Q9FK91, PARP3_ARATH;
DR   Q9Y6F1, PARP3_HUMAN;  Q1SGF1, PARP3_MEDTR;  Q0E0Q3, PARP3_ORYSJ;
DR   Q9SWB4, PARP3_SOYBN;  Q9UKK3, PARP4_HUMAN;  Q2NL67, PARP6_HUMAN;
DR   Q6P6P7, PARP6_MOUSE;  Q5RDU4, PARP6_PONAB;  Q8N3A8, PARP8_HUMAN;
DR   Q3UD82, PARP8_MOUSE;  Q8IXQ6, PARP9_HUMAN;  Q8CAS9, PARP9_MOUSE;
DR   Q7Z3E1, PARPT_HUMAN;  Q8C1B2, PARPT_MOUSE;  P35875, PARP_DROME ;
DR   O55721, PARP_IIV6  ;  Q11208, PARP_SARPE ;  Q9N4H4, PME1_CAEEL ;
DR   Q09525, PME2_CAEEL ;  Q9TXQ1, PME5_CAEEL ;  Q5Z8Q9, PRP2A_ORYSJ;
DR   Q0JMY1, PRP2B_ORYSJ;  O95271, TNKS1_HUMAN;  Q6PFX9, TNKS1_MOUSE;
DR   Q9H2K2, TNKS2_HUMAN;  Q3UES3, TNKS2_MOUSE;  Q54YW4, Y8045_DICDI;
//
ID   2.4.2.31
DE   NAD(+)--protein-arginine ADP-ribosyltransferase.
AN   ADP-ribosyltransferase.
AN   Mono(ADP-ribosyl)transferase.
AN   Mono-ADP-ribosyltransferase.
AN   NAD(P)(+)--arginine ADP-ribosyltransferase.
AN   NAD(P)(+)--protein-arginine ADP-ribosyltransferase.
CA   (1) NAD(+) + protein-L-arginine = nicotinamide + N(omega)-(ADP-D-
CA   ribosyl)-protein-L-arginine.
CA   (2) NADP(+) + protein-L-arginine = nicotinamide + N(omega)-((2'-phospho-
CA   ADP)-D-ribosyl)-protein-L-arginine.
CC   -!- Arginine residues in proteins act as acceptors.
CC   -!- Free arginine, agmatine ((4-aminobutyl)guanidine), arginine methyl
CC       ester and guanidine can also do so.
CC   -!- Catalyzes the NAD(+)-dependent activation of EC 4.6.1.1.
CC   -!- Some bacterial enterotoxins possess similar enzymatic activities (cf.
CC       EC 2.4.2.36).
PR   PROSITE; PDOC00993;
DR   A2PU44, CHELT_VIBCH;  Q838U8, EFV_ENTFA  ;  A0QLI5, MAV_MYCA1  ;
DR   P52961, NAR1_HUMAN ;  Q60935, NAR1_MOUSE ;  Q03515, NAR1_RABIT ;
DR   P17981, NAR2A_MOUSE;  P17982, NAR2A_RAT  ;  O35975, NAR2B_MOUSE;
DR   P20974, NAR2B_RAT  ;  Q13508, NAR3_HUMAN ;  Q8R2G4, NAR3_MOUSE ;
DR   Q93070, NAR4_HUMAN ;  Q95NE0, NAR4_PANTR ;  Q0VC22, NAR5_BOVIN ;
DR   Q96L15, NAR5_HUMAN ;  P70352, NAR5_MOUSE ;  Q5XHY4, NAR5_RAT   ;
DR   Q92080, NARE_CHICK ;  P55806, NRT1_CHICK ;  P55807, NRT2_CHICK ;
DR   Q7N8B1, PHXA_PHOLL ;  P17450, SPVB_SALCH ;  P24419, SPVB_SALDU ;
DR   P55220, SPVB_SALEN ;  D0ZHS9, SPVB_SALT1 ;  P21454, SPVB_SALTY ;
DR   A3UNN4, VIS_VIBSP  ;
//
ID   2.4.2.32
DE   Dolichyl-phosphate D-xylosyltransferase.
CA   UDP-D-xylose + dolichyl phosphate = UDP + dolichyl D-xylosyl phosphate.
//
ID   2.4.2.33
DE   Dolichyl-xylosyl-phosphate--protein xylosyltransferase.
CA   Dolichyl D-xylosyl phosphate + protein = dolichyl phosphate +
CA   D-xylosylprotein.
//
ID   2.4.2.34
DE   Indolylacetylinositol arabinosyltransferase.
AN   Arabinosylindolylacetylinositol synthase.
CA   UDP-L-arabinose + (indol-3-yl)acetyl-1D-myo-inositol = UDP + (indol-3-
CA   yl)acetyl-myo-inositol 3-L-arabinoside.
CC   -!- The position of acylation is indeterminate because of the ease of
CC       acyl transfer between hydroxy groups.
//
ID   2.4.2.35
DE   Flavonol-3-O-glycoside xylosyltransferase.
CA   UDP-D-xylose + a flavonol 3-O-glycoside = UDP + a flavonol 3-(beta-D-
CA   xylosyl-(1->2)-beta-D-glycoside).
CC   -!- Flavonol 3-O-glucoside, flavonol 3-O-galactoside and, more slowly,
CC       rutin, can act as acceptors.
//
ID   2.4.2.36
DE   NAD(+)--diphthamide ADP-ribosyltransferase.
AN   ADP-ribosyltransferase.
AN   Mono(ADP-ribosyl)transferase.
CA   NAD(+) + peptide diphthamide = nicotinamide + peptide N-(ADP-D-
CA   ribosyl)diphthamide.
CC   -!- Diphtheria toxin and some other bacterial toxins catalyze this
CC       reaction.
CC   -!- The acceptor is a diphthamide residue in elongation factor 2 (cf.
CC       EC 2.4.2.31).
DR   P01555, CHTA_VIBCH ;  Q5EK40, CHXA_VIBCH ;  P00588, DTX_CORBE  ;
DR   P00587, DTX_COROM  ;  P11439, TOXA_PSEAE ;
//
ID   2.4.2.37
DE   NAD(+)--dinitrogen-reductase ADP-D-ribosyltransferase.
AN   NAD--azoferredoxin (ADPribose)transferase.
AN   NAD--dinitrogen-reductase ADP-D-ribosyltransferase.
CA   NAD(+) + [dinitrogen reductase] = nicotinamide + ADP-D-ribosyl-
CA   [dinitrogen reductase].
CC   -!- Together with EC 3.2.2.24, controls the level of activity of
CC       EC 1.18.6.1.
DR   P14299, DRAT_RHORU ;
//
ID   2.4.2.38
DE   Glycoprotein 2-beta-D-xylosyltransferase.
AN   Beta-1,2-xylosyltransferase.
CA   UDP-D-xylose + N(4)-(N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-
CA   mannosyl-(1->3)-(N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-
CA   (1->6))-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-
CA   acetyl-beta-D-glucosaminyl)asparagine = UDP + N(4)-(N-acetyl-beta-D-
CA   glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-(N-acetyl-beta-D-
CA   glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6))-(beta-D-xylosyl-(1->2))-
CA   beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-
CA   D-glucosaminyl)asparagine.
CC   -!- Specific for N-linked oligosaccharides (N-glycans).
DR   Q9LDH0, XYLT_ARATH ;
//
ID   2.4.2.39
DE   Xyloglucan 6-xylosyltransferase.
AN   Uridine diphosphoxylose-xyloglucan 6-alpha-xylosyltransferase.
AN   Xyloglucan 6-alpha-D-xylosyltransferase.
CA   Transfers an alpha-D-xylosyl residue from UDP-D-xylose to a glucose
CA   residue in xyloglucan, forming an alpha-(1->6)-D-xylosyl-D-glucose
CA   linkage.
CC   -!- In association with EC 2.4.1.168 this enzyme brings about the
CC       synthesis of xyloglucan.
CC   -!- Concurrent transfers of glucose and xylose are necessary for this
CC       synthesis.
CC   -!- Formerly EC 2.4.1.169.
DR   Q9LZJ3, XT1_ARATH  ;
//
ID   2.4.2.40
DE   Zeatin O-beta-D-xylosyltransferase.
AN   Uridine diphosphoxylose-zeatin xylosyltransferase.
AN   Zeatin O-xylosyltransferase.
CA   UDP-D-xylose + zeatin = UDP + O-beta-D-xylosylzeatin.
CC   -!- Does not act on UDP-glucose (cf. EC 2.4.1.103).
CC   -!- Formerly EC 2.4.1.204.
DR   P56725, ZOX_PHAVU  ;
//
ID   2.4.2.41
DE   Xylogalacturonan beta-1,3-xylosyltransferase.
AN   XGA xylosyltransferase.
AN   Xylogalacturonan xylosyltransferase.
CA   Transfers a xylosyl residue from UDP-D-xylose to a D-galactose residue in
CA   xylogalacturonan, forming a beta-1,3-D-xylosyl-D-galactose linkage.
CC   -!- Involved in plant cell wall synthesis.
CC   -!- The enzyme from Arabidopsis thaliana could transfer D-xylose from
CC       UDP-D-xylose onto oligogalacturonide acceptors.
CC   -!- The enzyme did not show significant activity with UDP-glucose, UDP-
CC       galactose, or UDP-N-acetyl-D-glucosamine as sugar donors.
DR   Q94AA9, XGD1_ARATH ;
//
ID   2.4.2.42
DE   UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase.
AN   Beta-glucoside alpha-1,3-xylosyltransferase.
CA   UDP-D-xylose + Glc-beta-Ser(53)-EGF-like domain of bovine factor
CA   IX(45-87) = UDP + Xyl-alpha(1-3)Glc-beta-Ser(53)-EGF-like domain of
CA   bovine factor IX(45-87).
CC   -!- The enzyme is involved in the biosynthesis of the Xyl-alpha(1-3)Xyl-
CC       alpha(1-3)Glc-beta-1-O-Ser on epidermal growth factor-like domains.
//
ID   2.4.2.43
DE   Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase.
AN   4-amino-4-deoxy-L-arabinose lipid A transferase.
AN   Lipid A 4-amino-4-deoxy-L-arabinosyltransferase.
AN   Polymyxin resistance protein PmrK.
AN   Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl
AN   transferase.
AN   Undecaprenyl phosphate-alpha-L-Ara4N transferase.
CA   4-amino-4-deoxy-alpha-L-arabinose di-trans,poly-cis-undecaprenyl
CA   phosphate + lipid IV(A) = lipid II(A) + di-trans,poly-cis-undecaprenyl
CA   phosphate.
CC   -!- Formerly EC 2.4.2.n1.
DR   B4EUL1, ARNT1_PROMH;  Q4KC80, ARNT1_PSEF5;  Q3KCC9, ARNT1_PSEPF;
DR   Q2NWA9, ARNT1_SODGM;  B4ETL9, ARNT2_PROMH;  Q4K884, ARNT2_PSEF5;
DR   Q3KCB9, ARNT2_PSEPF;  Q2NRV9, ARNT2_SODGM;  A0KGY4, ARNT_AERHH ;
DR   A4SQX1, ARNT_AERS4 ;  A7ZP75, ARNT_ECO24 ;  B7UFR9, ARNT_ECO27 ;
DR   B7MG24, ARNT_ECO45 ;  B7LAS2, ARNT_ECO55 ;  Q8XDZ1, ARNT_ECO57 ;
DR   B5YXQ0, ARNT_ECO5E ;  B7NNT6, ARNT_ECO7I ;  B7MXT9, ARNT_ECO81 ;
DR   B7M5T9, ARNT_ECO8A ;  B1X8X0, ARNT_ECODH ;  A8A2C4, ARNT_ECOHS ;
DR   A1ADA9, ARNT_ECOK1 ;  Q0TFI5, ARNT_ECOL5 ;  Q8FFL9, ARNT_ECOL6 ;
DR   B1IXT0, ARNT_ECOLC ;  P76473, ARNT_ECOLI ;  B7N5M2, ARNT_ECOLU ;
DR   B6I7K0, ARNT_ECOSE ;  B1LLL1, ARNT_ECOSM ;  Q1R9F8, ARNT_ECOUT ;
DR   C5BDQ8, ARNT_EDWI9 ;  A4WAM1, ARNT_ENT38 ;  Q6D2F3, ARNT_ERWCT ;
DR   B2VBI7, ARNT_ERWT9 ;  B7LM74, ARNT_ESCF3 ;  B5XTL1, ARNT_KLEP3 ;
DR   A6TF96, ARNT_KLEP7 ;  C6DAW3, ARNT_PECCP ;  Q7N3Q9, ARNT_PHOLL ;
DR   Q48HY9, ARNT_PSE14 ;  A6V1N8, ARNT_PSEA7 ;  B7VBN0, ARNT_PSEA8 ;
DR   Q02R27, ARNT_PSEAB ;  Q9HY61, ARNT_PSEAE ;  Q4ZSZ0, ARNT_PSEU2 ;
DR   B5EZI0, ARNT_SALA4 ;  A9MJC5, ARNT_SALAR ;  Q57M54, ARNT_SALCH ;
DR   B5FNU1, ARNT_SALDC ;  B5R274, ARNT_SALEP ;  B5RCC6, ARNT_SALG2 ;
DR   B4TBG8, ARNT_SALHS ;  B4SYX3, ARNT_SALNS ;  Q5PNA8, ARNT_SALPA ;
DR   A9N5B0, ARNT_SALPB ;  C0Q067, ARNT_SALPC ;  B5BCP4, ARNT_SALPK ;
DR   B4TPI4, ARNT_SALSV ;  Q8Z538, ARNT_SALTI ;  O52327, ARNT_SALTY ;
DR   A8GDR9, ARNT_SERP5 ;  A8FRR0, ARNT_SHESH ;  B2TW40, ARNT_SHIB3 ;
DR   Q31YK0, ARNT_SHIBS ;  Q32DT1, ARNT_SHIDS ;  Q0T2M6, ARNT_SHIF8 ;
DR   Q83KB6, ARNT_SHIFL ;  Q3YZU9, ARNT_SHISS ;  Q8D339, ARNT_WIGBR ;
DR   A1JPM4, ARNT_YERE8 ;  A7FHH6, ARNT_YERP3 ;  Q1C744, ARNT_YERPA ;
DR   B2K5L1, ARNT_YERPB ;  Q8ZDX9, ARNT_YERPE ;  A9R091, ARNT_YERPG ;
DR   Q1CIH9, ARNT_YERPN ;  A4TIM6, ARNT_YERPP ;  Q66A06, ARNT_YERPS ;
DR   B1JJ32, ARNT_YERPY ;
//
ID   2.4.2.n1
DE   Transferred entry: 2.4.2.43.
//
ID   2.4.99.1
DE   Beta-galactoside alpha-2,6-sialyltransferase.
AN   Beta-galactosamide alpha-2,6-sialyltransferase.
AN   CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase.
CA   CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-
CA   glucosamine = CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-
CA   acetyl-beta-D-glucosamine.
CC   -!- The terminal beta-D-galactosyl residue of the oligosaccharide of
CC       glycoproteins, as well as lactose, can act as acceptor.
DR   Q92182, SIAT1_CHICK;  P15907, SIAT1_HUMAN;  Q64685, SIAT1_MOUSE;
DR   P13721, SIAT1_RAT  ;  A5D7T4, SIAT2_BOVIN;  Q701R0, SIAT2_CHICK;
DR   Q701R2, SIAT2_DANRE;  Q96JF0, SIAT2_HUMAN;  Q76K27, SIAT2_MOUSE;
DR   Q5K027, SIAT2_ORYLA;  Q701R4, SIAT2_PANTR;  Q701R3, SIAT2_RAT  ;
DR   Q5QQ37, SIAT2_TAKRU;  Q701R1, SIAT2_XENTR;
//
ID   2.4.99.2
DE   Monosialoganglioside sialyltransferase.
CA   CMP-N-acetylneuraminate + D-galactosyl-N-acetyl-D-galactosaminyl-
CA   (N-acetylneuraminyl)-D-galactosyl-D-glucosyl-(1<->1)-ceramide = CMP +
CA   N-acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-
CA   (N-acetylneuraminyl)-D-galactosyl-D-glucosyl-(1<->1)-ceramide.
CC   -!- May be identical with EC 2.4.99.4.
//
ID   2.4.99.3
DE   Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase.
AN   GalNAc alpha-2,6-sialyltransferase I.
CA   CMP-N-acetylneuraminate + glycano-(1->3)-(N-acetyl-alpha-D-
CA   galactosaminyl)-glycoprotein = CMP + glycano-((2->6)-alpha-N-
CA   acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein.
CC   -!- Alpha-N-acetylgalactosamine linked to threonine or serine is also an
CC       acceptor, when substituted at the 3-position.
DR   Q92183, SIA7A_CHICK;  Q9NSC7, SIA7A_HUMAN;  Q9QZ39, SIA7A_MOUSE;
//
ID   2.4.99.4
DE   Beta-galactoside alpha-2,3-sialyltransferase.
AN   CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase.
CA   CMP-N-acetylneuraminate + beta-D-galactosyl-1,3-N-acetyl-alpha-D-
CA   galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-
CA   1,3-N-acetyl-alpha-D-galactosaminyl-R.
CC   -!- The acceptor is Gal-beta-1,3-GalNAc-R, where R is H, a threonine or
CC       serine residue in a glycoprotein, or a glycolipid.
CC   -!- Lactose can also act as acceptor.
CC   -!- May be identical with EC 2.4.99.2.
DR   Q11200, SIA4A_CHICK;  Q11201, SIA4A_HUMAN;  P54751, SIA4A_MOUSE;
DR   Q6KB59, SIA4A_PANTR;  Q02745, SIA4A_PIG  ;  Q16842, SIA4B_HUMAN;
DR   Q11204, SIA4B_MOUSE;  Q6KB58, SIA4B_PANTR;  Q11205, SIA4B_RAT  ;
//
ID   2.4.99.5
DE   Galactosyldiacylglycerol alpha-2,3-sialyltransferase.
CA   CMP-N-acetylneuraminate + 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol =
CA   CMP + 1,2-diacyl-3-(3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl)-
CA   sn-glycerol.
CC   -!- The beta-D-galactosyl residue of the oligosaccharide of glycoproteins
CC       may also act as acceptor.
//
ID   2.4.99.6
DE   N-acetyllactosaminide alpha-2,3-sialyltransferase.
CA   CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-N-acetyl-D-
CA   glucosaminyl-glycoprotein = CMP + alpha-N-acetylneuraminyl-(2->3)-beta-D-
CA   galactosyl-(1->4)-N-acetyl-D-glucosaminyl-glycoprotein.
CC   -!- Acts on beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl termini on
CC       glycoprotein.
DR   Q11203, SIAT6_HUMAN;  P97325, SIAT6_MOUSE;  P61132, SIAT6_PANTR;
DR   Q02734, SIAT6_RAT  ;
//
ID   2.4.99.7
DE   Alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetylgalactosaminide
DE   6-alpha-sialyltransferase.
AN   Alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide
AN   alpha-2,6-sialyltransferase.
AN   Cytidine monophosphoacetylneuraminate-(alpha-N-acetylneuraminyl-2,3-beta-
AN   galactosyl-1,3)-N-acetylgalactosaminide-alpha-2,6-sialyltransferase.
AN   NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase.
AN   Sialyltransferase.
AN   Sialyltransferase 3C.
AN   Sialyltransferase 7D.
AN   ST6GALNAC.
CA   CMP-N-acetylneuraminate + N-acetyl-alpha-neuraminyl-(2->3)-beta-D-
CA   galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R = CMP + N-acetyl-alpha-
CA   neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-(N-acetyl-alpha-neuraminyl-
CA   (2->6))-N-acetyl-D-galactosaminyl-R.
CC   -!- Attaches N-acetylneuraminic acid in alpha-2,6-linkage to N-acetyl-
CC       galactosamine only when present in the structure of alpha-N-acetyl-
CC       neuraminyl-(2->3)-beta-galactosyl-(1->3)-N-acetylgalactosaminyl-R,
CC       where R may be protein or p-nitrophenol.
CC   -!- Not identical with EC 2.4.99.3.
DR   Q9H4F1, SIA7D_HUMAN;  Q9R2B6, SIA7D_MOUSE;
//
ID   2.4.99.8
DE   Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase.
AN   Alpha-2,8-sialyltransferase.
CA   CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-
CA   galactosyl-R = CMP + alpha-N-acetylneuraminyl-(2->8)-alpha-N-
CA   acetylneuraminyl-(2->3)-beta-D-galactosyl-R.
CC   -!- Gangliosides act as acceptors.
DR   Q6ZXD2, SIA8A_BOVIN;  Q92185, SIA8A_HUMAN;  Q64687, SIA8A_MOUSE;
DR   P61642, SIA8A_PANTR;  Q6ZXA0, SIA8A_XENLA;  Q6DNG6, SIA8A_XENTR;
//
ID   2.4.99.9
DE   Lactosylceramide alpha-2,3-sialyltransferase.
AN   Ganglioside GM3 synthase.
CA   CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-beta-D-glucosyl-
CA   (1<->1)-ceramide = CMP + alpha-N-acetylneuraminyl-(2->3)-beta-D-
CA   galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide.
CC   -!- Lactose cannot act as acceptor.
DR   Q70D51, SIAT9_BOVIN;  Q9UNP4, SIAT9_HUMAN;  O88829, SIAT9_MOUSE;
DR   Q6KB55, SIAT9_PANTR;  Q68G12, SIAT9_RAT  ;
//
ID   2.4.99.10
DE   Neolactotetraosylceramide alpha-2,3-sialyltransferase.
AN   Sialyltransferase.
CA   CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-
CA   glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-D-glucosyl-(1<->1)-ceramide
CA   = CMP + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-
CA   acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-D-glucosyl-
CA   (1<->1)-ceramide.
//
ID   2.4.99.11
DE   Lactosylceramide alpha-2,6-N-sialyltransferase.
CA   CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-beta-D-glucosyl-
CA   (1<->1)-ceramide = CMP + alpha-N-acetylneuraminyl-(2->6)-beta-D-
CA   galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide.
//
ID   2.4.99.12
DE   Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase.
AN   3-deoxy-D-manno-oct-2-ulosonic acid transferase.
AN   3-deoxy-manno-octulosonic acid transferase.
AN   KDO transferase.
AN   Lipid IV(A) KDO transferase.
CA   2-deoxy-2-(((3R)-3-hydroxypentadecanoyl)amino)-3-O-((3R)-3-
CA   hydroxytetradecanoyl)-4-O-phosphono-beta-D-glucopyranosyl-(1->6)-2-deoxy-
CA   3-O-((3R)-3-hydroxytetradecanoyl)-2-(((3R)-3-hydroxytetradecanoyl)amino)-
CA   1-O-phosphono-alpha-D-glucopyranose + CMP-3-deoxy-D-manno-octulosonate =
CA   3-deoxy-alpha-D-manno-oct-2-ulopyranosyl-(2->6)-2-deoxy-2-(((3R)-3-
CA   hydroxypentadecanoyl)amino)-3-O-((3R)-3-hydroxytetradecanoyl)-4-
CA   O-phosphono-beta-D-glucopyranosyl-(1->6)-2-deoxy-3-O-((3R)-3-
CA   hydroxytetradecanoyl)-2-(((3R)-3-hydroxytetradecanoyl)amino)-1-
CA   O-phosphono-alpha-D-glucopyranose + CMP.
CC   -!- The bifunctional enzyme from Escherichia coli transfers two 3-deoxy-
CC       D-manno-octulosonate residues to lipid IV(A) (cf. EC 2.4.99.13).
CC   -!- The monofunctional enzymes from Aquifex aeolicus and Haemophilus
CC       influenzae catalyze the transfer of a single 3-deoxy-D-manno-
CC       octulosonate residue from CMP-3-deoxy-D-manno-octulosonate to lipid
CC       IV(A).
CC   -!- The enzymes from Chlamydia transfer three or more 3-deoxy-D-manno-
CC       octulosonate residues and generate genus-specific epitopes.
//
ID   2.4.99.13
DE   (KDO)-lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase.
AN   3-deoxy-D-manno-oct-2-ulosonic acid transferase.
AN   3-deoxy-manno-octulosonic acid transferase.
AN   KDO transferase.
CA   3-deoxy-alpha-D-manno-oct-2-ulopyranosyl-(2->6)-2-deoxy-2-(((3R)-3-
CA   hydroxypentadecanoyl)amino)-3-O-((3R)-3-hydroxytetradecanoyl)-4-
CA   O-phosphono-beta-D-glucopyranosyl-(1->6)-2-deoxy-3-O-((3R)-3-
CA   hydroxytetradecanoyl)-2-(((3R)-3-hydroxytetradecanoyl)amino)-1-
CA   O-phosphono-alpha-D-glucopyranose + CMP-3-deoxy-D-manno-octulosonate =
CA   3-deoxy-alpha-D-manno-oct-2-ulopyranosyl-(2->4)-3-deoxy-alpha-D-manno-
CA   oct-2-ulopyranosyl-(2->6)-2-deoxy-2-(((3R)-3-hydroxypentadecanoyl)amino)-
CA   3-O-((3R)-3-hydroxytetradecanoyl)-4-O-phosphono-beta-D-glucopyranosyl-
CA   (1->6)-2-deoxy-3-O-((3R)-3-hydroxytetradecanoyl)-2-(((3R)-3-
CA   hydroxytetradecanoyl)amino)-1-O-phosphono-alpha-D-glucopyranose + CMP.
CC   -!- The bifunctional enzyme from Escherichia coli transfers two 3-deoxy-
CC       D-manno-octulosonate residues to lipid IV(A) (cf. EC 2.4.99.12).
CC   -!- The enzymes from Chlamydia transfer three or more 3-deoxy-D-manno-
CC       octulosonate residues and generate genus-specific epitopes.
//
ID   2.4.99.14
DE   (KDO)(2)-lipid IV(A) (2-8) 3-deoxy-D-manno-octulosonic acid transferase.
AN   3-deoxy-D-manno-oct-2-ulosonic acid transferase.
AN   3-deoxy-manno-octulosonic acid transferase.
AN   KDO transferase.
CA   3-deoxy-alpha-D-manno-oct-2-ulopyranosyl-(2->4)-3-deoxy-alpha-D-manno-
CA   oct-2-ulopyranosyl-(2->6)-2-deoxy-2-(((3R)-3-hydroxypentadecanoyl)amino)-
CA   3-O-((3R)-3-hydroxytetradecanoyl)-4-O-phosphono-beta-D-glucopyranosyl-
CA   (1->6)-2-deoxy-3-O-((3R)-3-hydroxytetradecanoyl)-2-(((3R)-3-
CA   hydroxytetradecanoyl)amino)-1-O-phosphono-alpha-D-glucopyranose + CMP-3-
CA   deoxy-D-manno-octulosonate = 3-deoxy-alpha-D-manno-oct-2-ulopyranosyl-
CA   (2->8)-3-deoxy-alpha-D-manno-oct-2-ulopyranosyl-(2->4)-3-deoxy-alpha-D-
CA   manno-oct-2-ulopyranosy[l-(2->6)-2-deoxy-2-(((3R)-3-
CA   hydroxypentadecanoyl)amino)-3-O-((3R)-3-hydroxytetradecanoyl)-4-
CA   O-phosphono-beta-D-glucopyrano]syl-(1->6)-2-deoxy-3-O-((3R)-3-
CA   hydroxytetradecanoyl)-2-((3R)-3-hydroxytetradecanoyl)amino-1-O-phosphono-
CA   alpha-D-glucopyranose + CMP.
CC   -!- The enzymes from Chlamydia transfer three or more 3-deoxy-D-manno-
CC       octulosonate residues and generate genus-specific epitopes.
//
ID   2.4.99.15
DE   (KDO)(3)-lipid IV(A) (2-4) 3-deoxy-D-manno-octulosonic acid transferase.
AN   3-deoxy-D-manno-oct-2-ulosonic acid transferase.
AN   3-deoxy-manno-octulosonic acid transferase.
AN   KDO transferase.
CA   3-deoxy-alpha-D-manno-oct-2-ulopyranosyl-(2->8)-3-deoxy-alpha-D-manno-
CA   oct-2-ulopyranosyl-(2->4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosyl-
CA   (2->6)-2-deoxy-2-(((3R)-3-hydroxypentadecanoyl)amino)-3-O-((3R)-3-
CA   hydroxytetradecanoyl)-4-O-phosphono-beta-D-glucopyranosyl-(1->6)-2-deoxy-
CA   3-O-((3R)-3-hydroxytetradecanoyl)-2-(((3R)-3-hydroxytetradecanoyl)amino)-
CA   1-O-phosphono-alpha-D-glucopyranose + CMP-3-deoxy-D-manno-octulosonate =
CA   3-deoxy-alpha-D-manno-oct-2-ulopyranosyl-(2->8)-(3-deoxy-alpha-D-manno-
CA   oct-2-ulopyranosyl-(2->4))-3-deoxy-alpha-D-manno-oct-2-ulopyranosyl-
CA   (2->4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosyl-(2->6)-2-deoxy-2-(((3R)-
CA   3-hydroxypentadecanoyl)amino)-3-O-((3R)-3-hydroxytetradecanoyl)-4-
CA   O-phosphono-beta-D-glucopyranosyl-(1->6)-2-deoxy-3-O-((3R)-3-
CA   hydroxytetradecanoyl)-2-(((3R)-3-hydroxytetradecanoyl)amino)-1-
CA   O-phosphono-alpha-D-glucopyranose + CMP.
CC   -!- The enzyme from Chlamydia psittaci transfers four KDO residues to
CC       lipid A, forming a branched tetrasaccharide with the structure alpha-
CC       KDO-(2,8)-(alpha-KDO-(2,4))-alpha-KDO-(2,4)-alpha-KDO (cf.
CC       EC 2.4.99.12, EC 2.4.99.13, and EC 2.4.99.14).
//
ID   2.5.1.1
DE   Dimethylallyltranstransferase.
AN   Dimethylallyltransferase.
AN   Geranyl-diphosphate synthase.
AN   Prenyltransferase.
CA   Dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate +
CA   geranyl diphosphate.
CC   -!- Will not accept larger prenyl diphosphates as efficient donors.
PR   PROSITE; PDOC00407;
DR   Q7XYS8, CHRDS_ARTSI;  Q09152, FPPS1_ARATH;  Q7XYS9, FPPS1_ARTSI;
DR   P49351, FPPS1_LUPAL;  O24241, FPPS1_PARAR;  Q43315, FPPS2_ARATH;
DR   Q7XYT0, FPPS2_ARTSI;  P49352, FPPS2_LUPAL;  O24242, FPPS2_PARAR;
DR   P49350, FPPS_ARTAN ;  Q8WMY2, FPPS_BOVIN ;  P08836, FPPS_CHICK ;
DR   Q92235, FPPS_GIBFU ;  O64905, FPPS_HELAN ;  P14324, FPPS_HUMAN ;
DR   P49349, FPPS_KLULA ;  P49353, FPPS_MAIZE ;  Q920E5, FPPS_MOUSE ;
DR   Q92250, FPPS_NEUCR ;  P05369, FPPS_RAT   ;  O14230, FPPS_SCHPO ;
DR   P08524, FPPS_YEAST ;  Q9NH03, FPS_DICDI  ;  P34802, GGPP1_ARATH;
DR   O04046, GGPP2_ARATH;  Q9LUD9, GGPP3_ARATH;  Q9SLG2, GGPP4_ARATH;
DR   O22043, GGPP6_ARATH;  Q9ZU77, GGPP7_ARATH;  Q9LRR0, GGPP8_ARATH;
DR   Q9LUE1, GGPP9_ARATH;  Q9LJY2, GGPPA_ARATH;  Q9LIA0, GGPPB_ARATH;
DR   Q9LHR4, GGPPC_ARATH;  Q758K0, GGPPS_ASHGO;  P56966, GGPPS_BOVIN;
DR   P80042, GGPPS_CAPAN;  Q42698, GGPPS_CATRO;  Q54BK1, GGPPS_DICDI;
DR   Q92236, GGPPS_GIBFU;  Q94ID7, GGPPS_HEVBR;  O95749, GGPPS_HUMAN;
DR   Q9WTN0, GGPPS_MOUSE;  P0A5H9, GGPPS_MYCBO;  P0A5H8, GGPPS_MYCTU;
DR   P24322, GGPPS_NEUCR;  Q6F596, GGPPS_RAT  ;  Q9P885, GGPPS_RHIRA;
DR   O59703, GGPPS_SCHPO;  Q43133, GGPPS_SINAL;  Q12051, GGPPS_YEAST;
DR   P39464, GGPS_SULAC ;  P95999, GGPS_SULSO ;  Q58270, IDSA_METJA ;
DR   O26156, IDSA_METTH ;  Q53479, IDSA_METTM ;  Q65164, TPRT_ASFB7 ;
DR   P0C9E2, TPRT_ASFK5 ;  Q8V9T7, TPRT_ASFM2 ;  P0C9E0, TPRT_ASFP4 ;
DR   P0C9E1, TPRT_ASFWA ;  Q55EU7, Y8742_DICDI;  Q54XP1, Y8823_DICDI;
//
ID   2.5.1.2
DE   Thiamine pyridinylase.
AN   Pyrimidine transferase.
AN   Thiaminase.
AN   Thiaminase I.
AN   Thiamine hydrolase.
AN   Thiamine pyridinolase.
AN   Thiamine:base 2-methyl-4-aminopyrimidine-5-methenyltransferase.
CA   Thiamine + pyridine = 1-((4-amino-2-methylpyrimidin-5-
CA   yl)methyl)pyridinium + 4-methyl-5-(2-hydroxyethyl)thiazole.
CC   -!- Various bases and thiol compounds can act instead of pyridine.
DR   P45741, THI1_PANTH ;
//
ID   2.5.1.3
DE   Thiamine-phosphate diphosphorylase.
AN   Thiamine-phosphate pyrophosphorylase.
AN   Thiamine-phosphate synthase.
AN   TMP diphosphorylase.
AN   TMP pyrophosphorylase.
CA   2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate + 4-methyl-5-
CA   (2-phosphono-oxyethyl)thiazole = diphosphate + thiamine phosphate.
DR   P61411, THE2_GEOSL ;  P40386, THI4_SCHPO ;  P41835, THI6_YEAST ;
DR   Q97RS5, THIE1_STRPN;  Q8DQK4, THIE1_STRR6;  P66920, THIE2_STRPN;
DR   P66921, THIE2_STRR6;  Q8G7X1, THIEC_BIFLO;  Q8FTH8, THIED_COREF;
DR   Q8NQH1, THIED_CORGL;  P61422, THIED_GEOSL;  Q1ILG3, THIE_ACIBL ;
DR   A0LTK3, THIE_ACIC1 ;  B7JBI2, THIE_ACIF2 ;  B5ERP0, THIE_ACIF5 ;
DR   B3GX82, THIE_ACTP7 ;  A6VPG9, THIE_ACTSZ ;  Q8UAS8, THIE_AGRT5 ;
DR   Q0VSP5, THIE_ALCBS ;  A6TMN5, THIE_ALKMQ ;  A8MK92, THIE_ALKOO ;
DR   Q2IM25, THIE_ANADE ;  B9MN52, THIE_ANATD ;  B7GKQ8, THIE_ANOFW ;
DR   O66833, THIE_AQUAE ;  O28205, THIE_ARCFU ;  Q5P6J5, THIE_AROAE ;
DR   A0JYP1, THIE_ARTS2 ;  A8IGE6, THIE_AZOC5 ;  A1KB60, THIE_AZOSB ;
DR   C1DMY6, THIE_AZOVD ;  A7ZA58, THIE_BACA2 ;  C3PBW1, THIE_BACAA ;
DR   C3L627, THIE_BACAC ;  A0R981, THIE_BACAH ;  Q81Z95, THIE_BACAN ;
DR   B7JN72, THIE_BACC0 ;  P61410, THIE_BACC1 ;  C1EVE6, THIE_BACC3 ;
DR   B7H7H5, THIE_BACC4 ;  B7HT70, THIE_BACC7 ;  A7GKR4, THIE_BACCN ;
DR   B9J2L5, THIE_BACCQ ;  Q81IG8, THIE_BACCR ;  Q63GK3, THIE_BACCZ ;
DR   Q5LCA7, THIE_BACFN ;  Q64TA1, THIE_BACFR ;  Q9KCY8, THIE_BACHD ;
DR   Q6HP17, THIE_BACHK ;  Q65DK0, THIE_BACLD ;  A8FIR6, THIE_BACP2 ;
DR   Q5WH87, THIE_BACSK ;  P39594, THIE_BACSU ;  Q8AA13, THIE_BACTN ;
DR   A6L645, THIE_BACV8 ;  A9VRN4, THIE_BACWK ;  Q2KUS6, THIE_BORA1 ;
DR   Q7WF72, THIE_BORBR ;  Q7W3U2, THIE_BORPA ;  Q7W049, THIE_BORPE ;
DR   A8M9N4, THIE_CALMQ ;  A4XG66, THIE_CALS8 ;  A8FMD4, THIE_CAMJ8 ;
DR   Q9PNL3, THIE_CAMJE ;  A1W068, THIE_CAMJJ ;  Q5HU23, THIE_CAMJR ;
DR   B0SUK3, THIE_CAUSK ;  A9WDL8, THIE_CHLAA ;  Q5L6R5, THIE_CHLAB ;
DR   Q824E9, THIE_CHLCV ;  B3ED41, THIE_CHLL2 ;  B3QNM2, THIE_CHLP8 ;
DR   A1BGM7, THIE_CHLPD ;  Q8KD79, THIE_CHLTE ;  Q7P1R3, THIE_CHRVO ;
DR   A8AKT0, THIE_CITK8 ;  Q97LQ9, THIE_CLOAB ;  A7FPT0, THIE_CLOB1 ;
DR   C3L061, THIE_CLOB6 ;  A6M1W6, THIE_CLOB8 ;  B2UY65, THIE_CLOBA ;
DR   B2TQ13, THIE_CLOBB ;  A5HYZ3, THIE_CLOBH ;  C1FSC1, THIE_CLOBJ ;
DR   B1IEG6, THIE_CLOBK ;  A7GAL0, THIE_CLOBL ;  B1KV12, THIE_CLOBM ;
DR   B8I3J4, THIE_CLOCE ;  Q186F8, THIE_CLOD6 ;  A0Q2A0, THIE_CLONN ;
DR   Q0TQV4, THIE_CLOP1 ;  Q8XKQ8, THIE_CLOPE ;  Q0STA1, THIE_CLOPS ;
DR   Q893R0, THIE_CLOTE ;  B5Y6I1, THIE_COPPD ;  Q8FP55, THIE_COREF ;
DR   Q4JVZ1, THIE_CORJK ;  Q478V2, THIE_DECAR ;  Q1IX16, THIE_DEIGD ;
DR   Q9RYX9, THIE_DEIRA ;  B8FUD4, THIE_DESHD ;  Q24XQ0, THIE_DESHY ;
DR   C4XIJ2, THIE_DESMR ;  B5YA97, THIE_DICT6 ;  B8E358, THIE_DICTD ;
DR   A7ZUK8, THIE_ECO24 ;  Q8X6Y0, THIE_ECO57 ;  B5Z089, THIE_ECO5E ;
DR   A8A793, THIE_ECOHS ;  A1AIG4, THIE_ECOK1 ;  Q0TA72, THIE_ECOL5 ;
DR   Q8FB78, THIE_ECOL6 ;  B1IUQ4, THIE_ECOLC ;  P30137, THIE_ECOLI ;
DR   B6I5K4, THIE_ECOSE ;  Q1R5V9, THIE_ECOUT ;  A4W5B6, THIE_ENT38 ;
DR   Q830K5, THIE_ENTFA ;  A7MJ80, THIE_ENTS8 ;  Q6DAM1, THIE_ERWCT ;
DR   Q2NB00, THIE_ERYLH ;  A5FJJ1, THIE_FLAJ1 ;  A6GWR9, THIE_FLAPJ ;
DR   Q8RI59, THIE_FUSNN ;  Q5KZU0, THIE_GEOKA ;  A4IN28, THIE_GEOTN ;
DR   Q7NNK8, THIE_GLOVI ;  Q4QNC6, THIE_HAEI8 ;  A5UA71, THIE_HAEIE ;
DR   A5UGT0, THIE_HAEIG ;  P71350, THIE_HAEIN ;  Q0I131, THIE_HAES1 ;
DR   A1WYL4, THIE_HALHL ;  Q5V0G6, THIE_HALMA ;  Q18GX9, THIE_HALWD ;
DR   Q1CT27, THIE_HELPH ;  Q9ZL01, THIE_HELPJ ;  B2USY5, THIE_HELPS ;
DR   O25514, THIE_HELPY ;  A9AZD9, THIE_HERA2 ;  B4U6B2, THIE_HYDS0 ;
DR   Q0BXD3, THIE_HYPNA ;  A6SUR1, THIE_JANMA ;  A6W6A2, THIE_KINRD ;
DR   A6TGQ0, THIE_KLEP7 ;  Q03NS1, THIE_LACBA ;  Q03CB2, THIE_LACC3 ;
DR   B3W783, THIE_LACCB ;  B2GBV5, THIE_LACF3 ;  Q9CG48, THIE_LACLA ;
DR   A2RKJ7, THIE_LACLM ;  Q02YS6, THIE_LACLS ;  Q890C0, THIE_LACPL ;
DR   A5VKA1, THIE_LACRD ;  B2G7Q4, THIE_LACRJ ;  Q38ZM1, THIE_LACSS ;
DR   C1DCM3, THIE_LARHH ;  Q1MRJ6, THIE_LAWIP ;  B0SE83, THIE_LEPBA ;
DR   B0SMR9, THIE_LEPBP ;  B1MX63, THIE_LEUCK ;  Q92EW5, THIE_LISIN ;
DR   C1KZ34, THIE_LISMC ;  Q723Y9, THIE_LISMF ;  B8DET0, THIE_LISMH ;
DR   Q8YA44, THIE_LISMO ;  A0AFC5, THIE_LISW6 ;  B1HX34, THIE_LYSSC ;
DR   Q65US7, THIE_MANSM ;  A1TYG6, THIE_MARAV ;  Q8TMD6, THIE_METAC ;
DR   A7IA09, THIE_METB6 ;  Q466J5, THIE_METBF ;  Q602R3, THIE_METCA ;
DR   Q1GXW1, THIE_METFK ;  Q2FM63, THIE_METHJ ;  A4FX32, THIE_METM5 ;
DR   A9AAG9, THIE_METM6 ;  A6VG83, THIE_METM7 ;  Q8PS49, THIE_METMA ;
DR   A3CS45, THIE_METMJ ;  P61413, THIE_METMP ;  A5ULP4, THIE_METS3 ;
DR   A6UPE6, THIE_METVS ;  Q2RGI8, THIE_MOOTA ;  A0QLT6, THIE_MYCA1 ;
DR   P66917, THIE_MYCBO ;  A1KFN6, THIE_MYCBP ;  A4T2R5, THIE_MYCGI ;
DR   B8ZU95, THIE_MYCLB ;  Q9ZBL5, THIE_MYCLE ;  B2HPZ9, THIE_MYCMM ;
DR   P61412, THIE_MYCPA ;  A0QQK7, THIE_MYCS2 ;  A3PTW9, THIE_MYCSJ ;
DR   A1UAB4, THIE_MYCSK ;  Q1BEL9, THIE_MYCSS ;  A5TZE0, THIE_MYCTA ;
DR   P66916, THIE_MYCTU ;  A0PRY2, THIE_MYCUA ;  A1T2Z5, THIE_MYCVP ;
DR   Q1D282, THIE_MYXXD ;  Q3IP34, THIE_NATPD ;  Q5F5C2, THIE_NEIG1 ;
DR   Q9JWI2, THIE_NEIMA ;  Q9JXF7, THIE_NEIMB ;  Q0AFV0, THIE_NITEC ;
DR   Q82UQ7, THIE_NITEU ;  Q2Y5Q6, THIE_NITMU ;  Q3JDH3, THIE_NITOC ;
DR   Q5YNP9, THIE_NOCFA ;  B2J6F7, THIE_NOSP7 ;  Q8YX72, THIE_NOSS1 ;
DR   Q8ESZ3, THIE_OCEIH ;  P57930, THIE_PASMU ;  Q03GM4, THIE_PEDPA ;
DR   Q3B4B1, THIE_PELLD ;  A5D4K4, THIE_PELTS ;  Q4FN35, THIE_PELUB ;
DR   C0QR82, THIE_PERMH ;  Q7N964, THIE_PHOLL ;  Q6KZH9, THIE_PICTO ;
DR   A2CB21, THIE_PROM3 ;  Q7VAV5, THIE_PROMA ;  B4EYU2, THIE_PROMH ;
DR   Q7V8I3, THIE_PROMM ;  Q7V0I3, THIE_PROMP ;  A4SEP8, THIE_PROVI ;
DR   Q48DP2, THIE_PSE14 ;  A6V0D3, THIE_PSEA7 ;  B7V9E0, THIE_PSEA8 ;
DR   Q02SE4, THIE_PSEAB ;  Q9HX40, THIE_PSEAE ;  Q1I4H6, THIE_PSEE4 ;
DR   Q4K5I7, THIE_PSEF5 ;  C3K2K2, THIE_PSEFS ;  A4XYV5, THIE_PSEMY ;
DR   A5W9G9, THIE_PSEP1 ;  Q3K6C1, THIE_PSEPF ;  B0KJV8, THIE_PSEPG ;
DR   Q88DP1, THIE_PSEPK ;  B1J1Y7, THIE_PSEPW ;  Q87VY6, THIE_PSESM ;
DR   Q4ZNA1, THIE_PSEU2 ;  A4VQX9, THIE_PSEU5 ;  A5WDP0, THIE_PSYWF ;
DR   Q9UZQ5, THIE_PYRAB ;  Q8U192, THIE_PYRFU ;  O58878, THIE_PYRHO ;
DR   O34294, THIE_RHIEC ;  Q7UQH1, THIE_RHOBA ;  B6INN5, THIE_RHOCS ;
DR   Q21VL5, THIE_RHOFD ;  A7NRF7, THIE_ROSCS ;  A5UUL3, THIE_ROSS1 ;
DR   Q21MI9, THIE_SACD2 ;  A4F727, THIE_SACEN ;  B5F1H6, THIE_SALA4 ;
DR   A8M4E6, THIE_SALAI ;  A9MHD7, THIE_SALAR ;  Q57H62, THIE_SALCH ;
DR   B5FQK8, THIE_SALDC ;  B5QYE8, THIE_SALEP ;  B5RFJ1, THIE_SALG2 ;
DR   B4TCT2, THIE_SALHS ;  B4T0Z5, THIE_SALNS ;  Q5PKA7, THIE_SALPA ;
DR   A9N0K5, THIE_SALPB ;  B5BJR2, THIE_SALPK ;  Q2S2A8, THIE_SALRD ;
DR   B4TQK3, THIE_SALSV ;  Q8Z325, THIE_SALTI ;  A4XBL2, THIE_SALTO ;
DR   Q9L9I8, THIE_SALTY ;  A8G8F3, THIE_SERP5 ;  B2TWI0, THIE_SHIB3 ;
DR   Q31U04, THIE_SHIBS ;  Q32AG6, THIE_SHIDS ;  Q0SY07, THIE_SHIF8 ;
DR   Q83PB9, THIE_SHIFL ;  Q3YUZ1, THIE_SHISS ;  A7X4S8, THIE_STAA1 ;
DR   A6U3H7, THIE_STAA2 ;  Q2FF35, THIE_STAA3 ;  Q2FWG3, THIE_STAA8 ;
DR   A5IUN7, THIE_STAA9 ;  Q2YUL2, THIE_STAAB ;  Q5HEA8, THIE_STAAC ;
DR   A6QIT5, THIE_STAAE ;  P66918, THIE_STAAM ;  P66919, THIE_STAAN ;
DR   Q6GEY4, THIE_STAAR ;  Q6G7L9, THIE_STAAS ;  Q8NVH5, THIE_STAAW ;
DR   Q9RGS5, THIE_STACT ;  Q5HMD0, THIE_STAEQ ;  Q8CNK2, THIE_STAES ;
DR   Q4L7X3, THIE_STAHJ ;  Q49Z39, THIE_STAS1 ;  Q3K1L6, THIE_STRA1 ;
DR   Q8E5W9, THIE_STRA3 ;  Q8E092, THIE_STRA5 ;  Q82AF9, THIE_STRAW ;
DR   Q9S2V2, THIE_STRCO ;  A4W0K4, THIE_STRS2 ;  A5GMH7, THIE_SYNPW ;
DR   Q7U5U1, THIE_SYNPX ;  Q3AL68, THIE_SYNSC ;  Q0AZ86, THIE_SYNWW ;
DR   P72965, THIE_SYNY3 ;  Q9HIQ4, THIE_THEAC ;  Q8DHK2, THIE_THEEB ;
DR   Q47R33, THIE_THEFY ;  Q72KL8, THIE_THET2 ;  Q5SKG9, THIE_THET8 ;
DR   Q8R806, THIE_THETN ;  Q97BE8, THIE_THEVO ;  Q3SFU7, THIE_THIDA ;
DR   B8GLE3, THIE_THISH ;  Q0W1L8, THIE_UNCMA ;  A7N7S3, THIE_VIBHB ;
DR   Q87JW8, THIE_VIBPA ;  Q7M9N9, THIE_WOLSU ;  Q8PH45, THIE_XANAC ;
DR   Q4UYA4, THIE_XANC8 ;  Q8P5R7, THIE_XANCP ;  A7IGG9, THIE_XANP2 ;
DR   Q9PGC4, THIE_XYLFA ;  Q87AX6, THIE_XYLFT ;  A7FNH7, THIE_YERP3 ;
DR   Q1C1U8, THIE_YERPA ;  Q8ZAQ1, THIE_YERPE ;  Q1CN71, THIE_YERPN ;
DR   A4TS25, THIE_YERPP ;  Q66FP6, THIE_YERPS ;  Q67T51, THIME_SYMTH;
//
ID   2.5.1.4
DE   Adenosylmethionine cyclotransferase.
CA   S-adenosyl-L-methionine = S-methyl-5'-thioadenosine + 2-aminobutan-4-
CA   olide.
//
ID   2.5.1.5
DE   Galactose-6-sulfurylase.
AN   Galactose-6-sulfatase.
AN   Porphyran sulfatase.
CA   Eliminates sulfate from the D-galactose 6-sulfate residues of porphyran,
CA   producing 3,6-anhydrogalactose residues.
//
ID   2.5.1.6
DE   Methionine adenosyltransferase.
AN   AdoMet synthetase.
AN   S-adenosylmethionine synthetase.
CA   ATP + L-methionine + H(2)O = phosphate + diphosphate + S-adenosyl-L-
CA   methionine.
CC   -!- Formerly EC 2.4.2.13.
PR   PROSITE; PDOC00369;
DR   P50301, METK1_ACTCH;  P23686, METK1_ARATH;  Q7XZR1, METK1_ATRNU;
DR   Q4H1G4, METK1_BETVU;  Q2KJC6, METK1_BOVIN;  P49611, METK1_BRAJU;
DR   O17680, METK1_CAEEL;  Q96551, METK1_CATRO;  Q56TU4, METK1_DAUCA;
DR   Q9AT56, METK1_ELAUM;  Q2J8P2, METK1_FRASC;  P50299, METK1_HORVU;
DR   Q00266, METK1_HUMAN;  Q91X83, METK1_MOUSE;  A2Y053, METK1_ORYSI;
DR   Q0DKY4, METK1_ORYSJ;  P49612, METK1_PEA  ;  P31155, METK1_PETCR;
DR   P48498, METK1_PETHY;  A9NUH8, METK1_PICSI;  Q9FVG8, METK1_PINCO;
DR   A9P822, METK1_POPTR;  P13444, METK1_RAT  ;  Q21A46, METK1_RHOPB;
DR   Q2RVX7, METK1_RHORT;  P43280, METK1_SOLLC;  Q307Y9, METK1_SOLTU;
DR   Q9M7K8, METK1_TOBAC;  A6XMY9, METK1_TRIMO;  A7PQS0, METK1_VITVI;
DR   P10659, METK1_YEAST;  P50302, METK2_ACTCH;  P17562, METK2_ARATH;
DR   Q6F3F3, METK2_ATRNU;  Q4H1G3, METK2_BETVU;  Q9FUZ1, METK2_BRAJU;
DR   Q96552, METK2_CATRO;  Q56TU3, METK2_DAUCA;  P24260, METK2_DIACA;
DR   Q9AT55, METK2_ELAUM;  Q2J843, METK2_FRASC;  Q4LB23, METK2_HORVU;
DR   P31153, METK2_HUMAN;  Q4R924, METK2_MACFA;  Q3THS6, METK2_MOUSE;
DR   P93438, METK2_ORYSJ;  P49613, METK2_PEA  ;  P31156, METK2_PETCR;
DR   Q9SBQ5, METK2_PETHY;  A9NYY0, METK2_PICSI;  Q9FVG7, METK2_PINCO;
DR   Q5R5H1, METK2_PONAB;  A9PDZ7, METK2_POPTR;  P18298, METK2_RAT  ;
DR   Q20YV7, METK2_RHOPB;  Q2RMS5, METK2_RHORT;  P43281, METK2_SOLLC;
DR   Q38JH8, METK2_SOLTU;  Q9FPL6, METK2_SUASA;  Q6SYB9, METK2_TOBAC;
DR   A7NVX9, METK2_VITVI;  P19358, METK2_YEAST;  P50303, METK3_ACTCH;
DR   Q9SJL8, METK3_ARATH;  Q6F3F0, METK3_ATRNU;  Q94FA6, METK3_BRAJU;
DR   P50305, METK3_CAEEL;  Q96553, METK3_CATRO;  Q4LB22, METK3_HORVU;
DR   Q9LGU6, METK3_ORYSJ;  Q9SBQ7, METK3_PETHY;  A9P2P4, METK3_PICSI;
DR   A9PEK8, METK3_POPTR;  P43282, METK3_SOLLC;  A7QJG1, METK3_VITVI;
DR   Q9LUT2, METK4_ARATH;  Q6F3F1, METK4_ATRNU;  Q94FA5, METK4_BRAJU;
DR   P50306, METK4_CAEEL;  Q4LB21, METK4_HORVU;  A9PHC5, METK4_POPTR;
DR   A7PRJ6, METK4_VITVI;  Q94FA4, METK5_BRAJU;  Q27522, METK5_CAEEL;
DR   A9PHE9, METK5_POPTR;  A7Q0V4, METK5_VITVI;  Q95032, METK_ACACA ;
DR   B0CG96, METK_ACAM1 ;  A9NF20, METK_ACHLI ;  A1TKT9, METK_ACIAC ;
DR   Q6FAQ6, METK_ACIAD ;  B2HYY9, METK_ACIBC ;  B0VR30, METK_ACIBS ;
DR   A3M4V2, METK_ACIBT ;  B0VC98, METK_ACIBY ;  A5FXD8, METK_ACICJ ;
DR   B9MDD1, METK_ACIET ;  B7J551, METK_ACIF2 ;  B5EN11, METK_ACIF5 ;
DR   A1W3X4, METK_ACISJ ;  A3N186, METK_ACTP2 ;  B3H1W3, METK_ACTP7 ;
DR   B0BQ17, METK_ACTPJ ;  A6VMK8, METK_ACTSZ ;  Q9YBK2, METK_AERPE ;
DR   B2UR09, METK_AKKM8 ;  Q0VL83, METK_ALCBS ;  Q0A6D3, METK_ALHEH ;
DR   B6EMV8, METK_ALISL ;  A8MJT0, METK_ALKOO ;  B4RWC7, METK_ALTMD ;
DR   O09486, METK_AMOPR ;  Q7WYG5, METK_AMOPS ;  B8J8T3, METK_ANAD2 ;
DR   Q2IM98, METK_ANADE ;  A7H6N1, METK_ANADF ;  B4ULF7, METK_ANASK ;
DR   B9MQ10, METK_ANATD ;  Q3MF32, METK_ANAVT ;  O67222, METK_AQUAE ;
DR   O30186, METK_ARCFU ;  Q5P2V5, METK_AROAE ;  P50304, METK_ASCIM ;
DR   B6YRP0, METK_AZOPC ;  A1K301, METK_AZOSB ;  C1DKE3, METK_AZOVD ;
DR   A7Z7Y9, METK_BACA2 ;  C3PCC4, METK_BACAA ;  C3LAZ9, METK_BACAC ;
DR   A0RJZ7, METK_BACAH ;  Q81KI0, METK_BACAN ;  B7JT32, METK_BACC0 ;
DR   Q72YV6, METK_BACC1 ;  B7IL28, METK_BACC2 ;  C1EW36, METK_BACC3 ;
DR   B7H9C7, METK_BACC4 ;  B7HSV6, METK_BACC7 ;  A7GU40, METK_BACCN ;
DR   B9J265, METK_BACCQ ;  Q816Q8, METK_BACCR ;  Q632S5, METK_BACCZ ;
DR   Q5LJ26, METK_BACFN ;  Q650L4, METK_BACFR ;  Q9K7Q9, METK_BACHD ;
DR   Q6HCB4, METK_BACHK ;  Q65FV8, METK_BACLD ;  A8FGH7, METK_BACP2 ;
DR   Q5WDZ8, METK_BACSK ;  P54419, METK_BACSU ;  Q8A2T6, METK_BACTN ;
DR   A6KZL1, METK_BACV8 ;  A9VLC6, METK_BACWK ;  Q1LU70, METK_BAUCH ;
DR   Q6MPK2, METK_BDEBA ;  B8DTW8, METK_BIFA0 ;  A1A0T9, METK_BIFAA ;
DR   B3DRM6, METK_BIFLD ;  Q8G3H4, METK_BIFLO ;  B7GUQ1, METK_BIFLS ;
DR   Q7VRG5, METK_BLOFL ;  Q493F2, METK_BLOPB ;  Q0SND7, METK_BORAP ;
DR   Q7WQX8, METK_BORBR ;  O50163, METK_BORBU ;  B7J1U8, METK_BORBZ ;
DR   Q661P3, METK_BORGA ;  Q7W200, METK_BORPA ;  A9IH21, METK_BORPD ;
DR   Q7VUL5, METK_BORPE ;  C0QXK7, METK_BRAHW ;  Q89HP5, METK_BRAJA ;
DR   Q5DNB1, METK_BRARP ;  A5ENA8, METK_BRASB ;  A4YYF1, METK_BRASO ;
DR   B8D9I9, METK_BUCA5 ;  P57486, METK_BUCAI ;  Q8K9E5, METK_BUCAP ;
DR   B8D7U1, METK_BUCAT ;  B1YPQ4, METK_BURA4 ;  Q1BSN9, METK_BURCA ;
DR   B1K0F2, METK_BURCC ;  A0KBF2, METK_BURCH ;  B4E800, METK_BURCJ ;
DR   Q0BAY8, METK_BURCM ;  A3MRQ4, METK_BURM7 ;  A2S860, METK_BURM9 ;
DR   Q62EZ1, METK_BURMA ;  A1V7L5, METK_BURMS ;  A3NQ73, METK_BURP0 ;
DR   Q3JX94, METK_BURP1 ;  A3N4I1, METK_BURP6 ;  B2JJY6, METK_BURP8 ;
DR   B2T1P7, METK_BURPP ;  Q63YH5, METK_BURPS ;  Q39BZ1, METK_BURS3 ;
DR   Q2T267, METK_BURTA ;  A4JIQ4, METK_BURVG ;  Q146W0, METK_BURXL ;
DR   A8MD44, METK_CALMQ ;  A4XHT8, METK_CALS8 ;  Q9LDQ7, METK_CAMSI ;
DR   Q3AFS4, METK_CARHZ ;  Q8GTL5, METK_CARPA ;  B3PGF2, METK_CELJU ;
DR   A9WGQ3, METK_CHLAA ;  Q3AQC3, METK_CHLCH ;  B3EDY2, METK_CHLL2 ;
DR   B3QMF6, METK_CHLP8 ;  A1BEZ3, METK_CHLPD ;  A8HYU5, METK_CHLRE ;
DR   B9LBJ9, METK_CHLSY ;  Q8KEG7, METK_CHLTE ;  Q1R0L1, METK_CHRSD ;
DR   Q7NZF9, METK_CHRVO ;  A8APG1, METK_CITK8 ;  A5CRX0, METK_CLAM3 ;
DR   B0REV4, METK_CLAMS ;  Q97F85, METK_CLOAB ;  A7FQI8, METK_CLOB1 ;
DR   B2UZL0, METK_CLOBA ;  B2TK10, METK_CLOBB ;  A5HY62, METK_CLOBH ;
DR   C1FQQ5, METK_CLOBJ ;  B1IE45, METK_CLOBK ;  A7G9S1, METK_CLOBL ;
DR   B1KST9, METK_CLOBM ;  B8I4C1, METK_CLOCE ;  Q18CL7, METK_CLOD6 ;
DR   A0Q2Y4, METK_CLONN ;  Q0TND4, METK_CLOP1 ;  A9KL72, METK_CLOPH ;
DR   Q0SR05, METK_CLOPS ;  Q898W7, METK_CLOTE ;  A3DHM4, METK_CLOTH ;
DR   Q486L6, METK_COLP3 ;  C3PG24, METK_CORA7 ;  P61945, METK_CORDI ;
DR   Q8FT48, METK_COREF ;  Q9K5E4, METK_CORGL ;  Q4JVH7, METK_CORJK ;
DR   C4LIT2, METK_CORK4 ;  B1VDN7, METK_CORU7 ;  B6J6H0, METK_COXB1 ;
DR   B6J3Q9, METK_COXB2 ;  A9KD87, METK_COXBN ;  A9N9E2, METK_COXBR ;
DR   Q83A78, METK_COXBU ;  Q0KF39, METK_CUPNH ;  Q476V0, METK_CUPPJ ;
DR   B1WZM0, METK_CYAA5 ;  B8HWM0, METK_CYAP4 ;  B7KFF5, METK_CYAP7 ;
DR   B7JX26, METK_CYAP8 ;  Q11PM7, METK_CYTH3 ;  Q47JN4, METK_DECAR ;
DR   Q3Z943, METK_DEHE1 ;  A5FRV2, METK_DEHSB ;  Q3ZZN7, METK_DEHSC ;
DR   C1CY25, METK_DEIDV ;  Q1J1P4, METK_DEIGD ;  Q9RWM6, METK_DEIRA ;
DR   A9BXF7, METK_DELAS ;  Q944U4, METK_DENCR ;  C6C1U5, METK_DESAD ;
DR   B1I6C4, METK_DESAP ;  Q311V1, METK_DESDG ;  B8FSB9, METK_DESHD ;
DR   C4XPZ6, METK_DESMR ;  A8ZYC8, METK_DESOH ;  Q6AQ43, METK_DESPS ;
DR   A4J945, METK_DESRM ;  Q729A3, METK_DESVH ;  B8DSC3, METK_DESVM ;
DR   A1VBJ1, METK_DESVV ;  Q54F07, METK_DICDI ;  A5EY13, METK_DICNV ;
DR   P40320, METK_DROME ;  A7ZR64, METK_ECO24 ;  B7UHY9, METK_ECO27 ;
DR   B7LFK4, METK_ECO55 ;  P0A819, METK_ECO57 ;  B5YQD9, METK_ECO5E ;
DR   B7NI05, METK_ECO7I ;  B7LYX2, METK_ECO8A ;  C5A0L1, METK_ECOBW ;
DR   B1XFA4, METK_ECODH ;  A8A481, METK_ECOHS ;  Q0TDR0, METK_ECOL5 ;
DR   P0A818, METK_ECOL6 ;  B1IT65, METK_ECOLC ;  P0A817, METK_ECOLI ;
DR   B7N7J5, METK_ECOLU ;  B6I780, METK_ECOSE ;  B1LDF1, METK_ECOSM ;
DR   C5BAV4, METK_EDWI9 ;  A4WE78, METK_ENT38 ;  Q837P9, METK_ENTFA ;
DR   A7MJQ6, METK_ENTS8 ;  Q6D081, METK_ERWCT ;  B2VF06, METK_ERWT9 ;
DR   Q2N5U2, METK_ERYLH ;  B7LPQ9, METK_ESCF3 ;  A7HJA9, METK_FERNB ;
DR   B0S2I6, METK_FINM2 ;  A5FJU1, METK_FLAJ1 ;  A6GWA9, METK_FLAPJ ;
DR   B0TX15, METK_FRAP2 ;  A8LE19, METK_FRASN ;  Q14JT0, METK_FRAT1 ;
DR   A7NEB4, METK_FRATF ;  Q2A1N2, METK_FRATH ;  B2SFE1, METK_FRATM ;
DR   A0Q862, METK_FRATN ;  Q0BKD0, METK_FRATO ;  Q5NIC7, METK_FRATT ;
DR   A4IWA4, METK_FRATW ;  Q8RGE5, METK_FUSNN ;  Q5KW02, METK_GEOKA ;
DR   Q39W48, METK_GEOMG ;  P61946, METK_GEOSL ;  C6E2L2, METK_GEOSM ;
DR   C5D6E9, METK_GEOSW ;  A4IRZ1, METK_GEOTN ;  A5GA66, METK_GEOUR ;
DR   Q7NHG0, METK_GLOVI ;  A9HE98, METK_GLUDA ;  Q5FSK6, METK_GLUOX ;
DR   A7L2Z6, METK_GOSHI ;  Q0BPF5, METK_GRABC ;  A0LY55, METK_GRAFK ;
DR   Q7VNG7, METK_HAEDU ;  Q4QLC5, METK_HAEI8 ;  A5UCT6, METK_HAEIE ;
DR   A5UIU0, METK_HAEIG ;  P43762, METK_HAEIN ;  B8F4B2, METK_HAEPS ;
DR   Q0I559, METK_HAES1 ;  B0UWT3, METK_HAES2 ;  Q2SLT3, METK_HAHCH ;
DR   Q5V2S5, METK_HALMA ;  B0R5A8, METK_HALS3 ;  Q9HQ73, METK_HALSA ;
DR   Q18H49, METK_HALWD ;  C4K3W7, METK_HAMD5 ;  Q17YQ7, METK_HELAH ;
DR   Q7VFY5, METK_HELHP ;  B6JPU7, METK_HELP2 ;  B5Z9W8, METK_HELPG ;
DR   Q1CUW4, METK_HELPH ;  Q9ZMN5, METK_HELPJ ;  B2US27, METK_HELPS ;
DR   P56460, METK_HELPY ;  A4G977, METK_HERAR ;  A2BIZ8, METK_HYPBU ;
DR   Q0C429, METK_HYPNA ;  Q5QVM7, METK_IDILO ;  A6T2Z1, METK_JANMA ;
DR   Q28UI9, METK_JANSC ;  B5XUA8, METK_KLEP3 ;  A6TDV1, METK_KLEP7 ;
DR   C5CD66, METK_KOSOT ;  Q5FIN8, METK_LACAC ;  Q03QA4, METK_LACBA ;
DR   Q03AU4, METK_LACC3 ;  B3WCC9, METK_LACCB ;  B2GDG2, METK_LACF3 ;
DR   A8YWU7, METK_LACH4 ;  Q74KS4, METK_LACJO ;  Q9CEE0, METK_LACLA ;
DR   A2RN40, METK_LACLM ;  Q02WN8, METK_LACLS ;  Q88XB8, METK_LACPL ;
DR   A5VL29, METK_LACRD ;  B2G8G3, METK_LACRJ ;  Q1WUT4, METK_LACS1 ;
DR   Q38YF8, METK_LACSS ;  C1DCT7, METK_LARHH ;  Q5X3N0, METK_LEGPA ;
DR   A5IDK5, METK_LEGPC ;  Q5ZTY6, METK_LEGPH ;  Q5WV18, METK_LEGPL ;
DR   O43938, METK_LEIIN ;  Q6AF79, METK_LEIXX ;  Q04SB8, METK_LEPBJ ;
DR   Q050E4, METK_LEPBL ;  B1Y6S3, METK_LEPCP ;  Q72SM5, METK_LEPIC ;
DR   Q8CXS7, METK_LEPIN ;  B1N092, METK_LEUCK ;  Q03VI4, METK_LEUMM ;
DR   Q92AZ5, METK_LISIN ;  C1KVW3, METK_LISMC ;  Q71Z03, METK_LISMF ;
DR   B8DFQ7, METK_LISMH ;  Q8Y6M0, METK_LISMO ;  A0AJB9, METK_LISW6 ;
DR   Q84MM2, METK_LITCN ;  Q2VYQ2, METK_MAGSA ;  A0LCX5, METK_MAGSM ;
DR   P80616, METK_MAIZE ;  Q65UT4, METK_MANSM ;  A1U547, METK_MARAV ;
DR   Q0ALW2, METK_MARMM ;  A6W3D6, METK_MARMS ;  A4ULF8, METK_MEDFA ;
DR   A4PU48, METK_MEDTR ;  P93254, METK_MESCR ;  Q6F1M6, METK_MESFL ;
DR   A6UU75, METK_META3 ;  Q8TU57, METK_METAC ;  A7I771, METK_METB6 ;
DR   Q46CW6, METK_METBF ;  Q12WC8, METK_METBU ;  B7KW92, METK_METC4 ;
DR   Q60CG7, METK_METCA ;  A9W731, METK_METEP ;  Q1H4X2, METK_METFK ;
DR   Q2FN14, METK_METHJ ;  Q58605, METK_METJA ;  Q8TV85, METK_METKA ;
DR   A4G0T1, METK_METM5 ;  A9A923, METK_METM6 ;  A6VHQ4, METK_METM7 ;
DR   Q8PWS4, METK_METMA ;  P0CW62, METK_METMI ;  P0CW63, METK_METMP ;
DR   B8IST7, METK_METNO ;  B1ZKT6, METK_METPB ;  A2SKW6, METK_METPP ;
DR   B1M4Z8, METK_METRJ ;  A5UMW7, METK_METS3 ;  B0UPH0, METK_METS4 ;
DR   Q2NEB3, METK_METST ;  O27429, METK_METTH ;  P26498, METK_METTM ;
DR   A0B742, METK_METTP ;  A6UQS6, METK_METVS ;  B0JUH1, METK_MICAN ;
DR   Q2RK28, METK_MOOTA ;  O22338, METK_MUSAC ;  A0QI26, METK_MYCA1 ;
DR   Q7U051, METK_MYCBO ;  A1KII1, METK_MYCBP ;  C1AN37, METK_MYCBT ;
DR   Q2SS11, METK_MYCCT ;  P47293, METK_MYCGE ;  A4TBZ0, METK_MYCGI ;
DR   B8ZUM2, METK_MYCLB ;  Q9CCQ4, METK_MYCLE ;  B2HP50, METK_MYCMM ;
DR   Q6MTB6, METK_MYCMS ;  Q741G5, METK_MYCPA ;  P78003, METK_MYCPN ;
DR   Q98PM0, METK_MYCPU ;  A0QWT3, METK_MYCS2 ;  Q4A5F4, METK_MYCS5 ;
DR   A3PZ71, METK_MYCSJ ;  A1UFL0, METK_MYCSK ;  Q7WYN1, METK_MYCSM ;
DR   Q1B9F3, METK_MYCSS ;  A5U294, METK_MYCTA ;  P77899, METK_MYCTU ;
DR   A0PPJ8, METK_MYCUA ;  A1T8H7, METK_MYCVP ;  Q84FD3, METK_MYXXA ;
DR   Q1CY83, METK_MYXXD ;  Q3IQF5, METK_NATPD ;  Q5FAC0, METK_NEIG1 ;
DR   B4RQ36, METK_NEIG2 ;  A9M1V8, METK_NEIM0 ;  Q9JVV6, METK_NEIMA ;
DR   Q9JY09, METK_NEIMB ;  A1KS98, METK_NEIMF ;  P48466, METK_NEUCR ;
DR   Q0AEV7, METK_NITEC ;  Q82WL2, METK_NITEU ;  Q1QJR5, METK_NITHX ;
DR   Q2Y5Z1, METK_NITMU ;  Q3J7R5, METK_NITOC ;  A6Q1Z8, METK_NITSB ;
DR   Q5YTN0, METK_NOCFA ;  A1SJF9, METK_NOCSJ ;  B2IUI4, METK_NOSP7 ;
DR   Q2GBP1, METK_NOVAD ;  Q8EP05, METK_OCEIH ;  Q04FL3, METK_OENOB ;
DR   A4S779, METK_OSTLU ;  Q00VB2, METK_OSTTA ;  A6LEL4, METK_PARD8 ;
DR   A1B374, METK_PARDP ;  A7HZ88, METK_PARL1 ;  P57897, METK_PASMU ;
DR   C6DFI3, METK_PECCP ;  Q03GG8, METK_PEDPA ;  Q3A388, METK_PELCD ;
DR   Q3B531, METK_PELLD ;  B4SD42, METK_PELPB ;  A5CYJ7, METK_PELTS ;
DR   Q4FNN1, METK_PELUB ;  A9BHX2, METK_PETMO ;  Q8W3Y4, METK_PHALU ;
DR   Q7N119, METK_PHOLL ;  Q6LMM8, METK_PHOPR ;  Q6L123, METK_PICTO ;
DR   P50300, METK_PINBN ;  A1VK01, METK_POLNA ;  B1XSH9, METK_POLNS ;
DR   Q12FG9, METK_POLSJ ;  A4T0F0, METK_POLSQ ;  P47916, METK_POPDE ;
DR   B2RLV1, METK_PORG3 ;  Q7MTQ0, METK_PORGI ;  Q6A8H3, METK_PROAC ;
DR   A3PB34, METK_PROM0 ;  A2C0F4, METK_PROM1 ;  A8G2X2, METK_PROM2 ;
DR   A2CBU3, METK_PROM3 ;  A9BDW6, METK_PROM4 ;  A2BUU2, METK_PROM5 ;
DR   Q31CL7, METK_PROM9 ;  Q7VDM7, METK_PROMA ;  B4F1A5, METK_PROMH ;
DR   Q7V5A2, METK_PROMM ;  Q7V2Y8, METK_PROMP ;  A2BPB2, METK_PROMS ;
DR   Q46H57, METK_PROMT ;  A4SF76, METK_PROVI ;  Q48CH3, METK_PSE14 ;
DR   Q15QK1, METK_PSEA6 ;  A6UZ09, METK_PSEA7 ;  B7V4D3, METK_PSEA8 ;
DR   Q02TL9, METK_PSEAB ;  Q9I5Z0, METK_PSEAE ;  Q1I3X6, METK_PSEE4 ;
DR   Q4K4I7, METK_PSEF5 ;  C3K3F5, METK_PSEFS ;  Q3IDQ1, METK_PSEHT ;
DR   A4XPF8, METK_PSEMY ;  A5WA00, METK_PSEP1 ;  Q3K5E8, METK_PSEPF ;
DR   B0KLZ1, METK_PSEPG ;  Q88D60, METK_PSEPK ;  B1J2Z8, METK_PSEPW ;
DR   Q88AK7, METK_PSESM ;  Q4ZM01, METK_PSEU2 ;  A4VRE8, METK_PSEU5 ;
DR   Q4FTH7, METK_PSYA2 ;  Q1QCH2, METK_PSYCK ;  A1SZJ9, METK_PSYIN ;
DR   A5WDU0, METK_PSYWF ;  Q9V1P7, METK_PYRAB ;  Q8ZYP7, METK_PYRAE ;
DR   A3MY01, METK_PYRCJ ;  Q8TZW1, METK_PYRFU ;  O59488, METK_PYRHO ;
DR   A1RSD7, METK_PYRIL ;  Q5JF22, METK_PYRKO ;  Q1LS34, METK_RALME ;
DR   B2UD22, METK_RALPJ ;  Q8Y347, METK_RALSO ;  Q98A80, METK_RHILO ;
DR   Q7URU7, METK_RHOBA ;  B6IVL6, METK_RHOCS ;  C0ZZD4, METK_RHOE4 ;
DR   Q21RM4, METK_RHOFD ;  C1B4J7, METK_RHOOB ;  Q2IZR2, METK_RHOP2 ;
DR   Q13AQ6, METK_RHOPS ;  A3PPW0, METK_RHOS1 ;  Q3IW86, METK_RHOS4 ;
DR   Q0S0L4, METK_RHOSR ;  A8GPW6, METK_RICAH ;  P56878, METK_RICPR ;
DR   Q9RL99, METK_RICTY ;  A7NFR6, METK_ROSCS ;  Q161H0, METK_ROSDO ;
DR   A5UQL0, METK_ROSS1 ;  Q21NJ5, METK_SACD2 ;  B5F5L4, METK_SALA4 ;
DR   A8LY25, METK_SALAI ;  A9MRD1, METK_SALAR ;  Q57K26, METK_SALCH ;
DR   B5FUK0, METK_SALDC ;  B5QY66, METK_SALEP ;  B5RE50, METK_SALG2 ;
DR   B4THH4, METK_SALHS ;  B4T5J6, METK_SALNS ;  Q5PJJ2, METK_SALPA ;
DR   B5BFP7, METK_SALPK ;  Q2RYY4, METK_SALRD ;  B4TV58, METK_SALSV ;
DR   P66765, METK_SALTI ;  A4X626, METK_SALTO ;  P66764, METK_SALTY ;
DR   O60198, METK_SCHPO ;  A8GIX9, METK_SERP5 ;  A1S9A6, METK_SHEAM ;
DR   B8E5U7, METK_SHEB2 ;  A3D0T8, METK_SHEB5 ;  A6WS79, METK_SHEB8 ;
DR   A9L1M6, METK_SHEB9 ;  Q12QA6, METK_SHEDO ;  Q087Q9, METK_SHEFN ;
DR   B0TUB8, METK_SHEHH ;  A3QAX5, METK_SHELP ;  Q8EIB4, METK_SHEON ;
DR   A8H0M7, METK_SHEPA ;  A4Y3R7, METK_SHEPC ;  B8CU43, METK_SHEPW ;
DR   A0L0K9, METK_SHESA ;  A8FRL1, METK_SHESH ;  Q0HM65, METK_SHESM ;
DR   Q0HRM1, METK_SHESR ;  A1RN71, METK_SHESW ;  B1KF18, METK_SHEWM ;
DR   B2U0W2, METK_SHIB3 ;  Q31WK4, METK_SHIBS ;  Q32C11, METK_SHIDS ;
DR   Q0T0V0, METK_SHIF8 ;  P0A820, METK_SHIFL ;  Q3YXS9, METK_SHISS ;
DR   Q5LLL2, METK_SILPO ;  Q1GK90, METK_SILST ;  Q2NRD1, METK_SODGM ;
DR   Q6GV10, METK_SOLBR ;  A9EXT3, METK_SORC5 ;  Q1GND0, METK_SPHAL ;
DR   A5VBQ3, METK_SPHWW ;  A7X3N2, METK_STAA1 ;  A6U2Q1, METK_STAA2 ;
DR   Q2FFV6, METK_STAA3 ;  Q2G1W4, METK_STAA8 ;  A5ITV6, METK_STAA9 ;
DR   Q2YTK1, METK_STAAB ;  Q5HEY9, METK_STAAC ;  A6QHX0, METK_STAAE ;
DR   P66766, METK_STAAM ;  P66767, METK_STAAN ;  Q6GFR6, METK_STAAR ;
DR   Q6G8E3, METK_STAAS ;  A8Z4L2, METK_STAAT ;  P50307, METK_STAAU ;
DR   Q8NVZ9, METK_STAAW ;  B9DN19, METK_STACT ;  Q5HNB8, METK_STAEQ ;
DR   Q8CNT5, METK_STAES ;  Q4L7C7, METK_STAHJ ;  Q49YL6, METK_STAS1 ;
DR   Q3K1M7, METK_STRA1 ;  Q8E5Y0, METK_STRA3 ;  Q8E0A3, METK_STRA5 ;
DR   Q827Q0, METK_STRAW ;  Q9L0Y3, METK_STRCO ;  C0M9M7, METK_STRE4 ;
DR   B4U228, METK_STREM ;  Q938W7, METK_STRFR ;  A8AWW6, METK_STRGC ;
DR   B1W470, METK_STRGG ;  B4SK03, METK_STRM5 ;  B2FPC7, METK_STRMK ;
DR   Q8DT23, METK_STRMU ;  Q99Z77, METK_STRP1 ;  Q04LE0, METK_STRP2 ;
DR   P0DF54, METK_STRP3 ;  B5E364, METK_STRP4 ;  Q5XBJ6, METK_STRP6 ;
DR   C1C6A5, METK_STRP7 ;  Q8P0G6, METK_STRP8 ;  Q1JB36, METK_STRPB ;
DR   Q1JL80, METK_STRPC ;  Q1JGA1, METK_STRPD ;  Q1J626, METK_STRPF ;
DR   A2RE06, METK_STRPG ;  B1IAT8, METK_STRPI ;  B8ZNB7, METK_STRPJ ;
DR   Q48SU7, METK_STRPM ;  Q97RN9, METK_STRPN ;  P0DF55, METK_STRPQ ;
DR   B2INE5, METK_STRPS ;  B5XM14, METK_STRPZ ;  Q8DQH0, METK_STRR6 ;
DR   A4W351, METK_STRS2 ;  C0MCM1, METK_STRS7 ;  Q9X4Q2, METK_STRST ;
DR   A3CNY4, METK_STRSV ;  A4VWU8, METK_STRSY ;  Q5LZI0, METK_STRT1 ;
DR   Q5M434, METK_STRT2 ;  B9DSM6, METK_STRU0 ;  C1CDB0, METK_STRZJ ;
DR   C1CJL0, METK_STRZP ;  C1CQM2, METK_STRZT ;  Q4JAL1, METK_SULAC ;
DR   Q30PN0, METK_SULDN ;  C3MZQ1, METK_SULIA ;  C4KIY2, METK_SULIK ;
DR   C3MJ04, METK_SULIL ;  C3MYC2, METK_SULIM ;  C3NF87, METK_SULIN ;
DR   C3N824, METK_SULIY ;  A6QBY6, METK_SULNB ;  Q980S9, METK_SULSO ;
DR   Q976F3, METK_SULTO ;  Q67T90, METK_SYMTH ;  Q31KC6, METK_SYNE7 ;
DR   A0LF65, METK_SYNFM ;  Q2JV74, METK_SYNJA ;  Q2JIN3, METK_SYNJB ;
DR   B1XPB0, METK_SYNP2 ;  Q5N1I9, METK_SYNP6 ;  A5GJ24, METK_SYNPW ;
DR   Q7U4S6, METK_SYNPX ;  A5GR07, METK_SYNR3 ;  Q0ICR7, METK_SYNS3 ;
DR   Q3AWE6, METK_SYNS9 ;  Q3AME2, METK_SYNSC ;  Q0AXL1, METK_SYNWW ;
DR   P72871, METK_SYNY3 ;  C5BTQ4, METK_TERTT ;  B7IEV2, METK_THEAB ;
DR   Q9HM12, METK_THEAC ;  Q8DK88, METK_THEEB ;  Q47R14, METK_THEFY ;
DR   C5A4B7, METK_THEGJ ;  A8F5B8, METK_THELT ;  A6LNU4, METK_THEM4 ;
DR   Q9X1Y8, METK_THEMA ;  B9K7H2, METK_THENN ;  B1YC36, METK_THENV ;
DR   B6YUL1, METK_THEON ;  A5ILS4, METK_THEP1 ;  B0KC73, METK_THEP3 ;
DR   B1LB17, METK_THESQ ;  Q72I53, METK_THET2 ;  Q5SHT8, METK_THET8 ;
DR   Q8RCE4, METK_THETN ;  Q97CT6, METK_THEVO ;  Q31EL0, METK_THICR ;
DR   Q3SFY2, METK_THIDA ;  Q73JR4, METK_TREDE ;  O83772, METK_TREPA ;
DR   B2S433, METK_TREPS ;  Q10VU5, METK_TRIEI ;  Q83HT7, METK_TROW8 ;
DR   Q83GE4, METK_TROWT ;  C5CQF1, METK_VARPS ;  A1WSC8, METK_VEREI ;
DR   A5F9H4, METK_VIBC3 ;  Q9KUP3, METK_VIBCH ;  C3LRY9, METK_VIBCM ;
DR   Q5E7R2, METK_VIBF1 ;  B5F9T2, METK_VIBFM ;  A7MTQ7, METK_VIBHB ;
DR   Q87LK6, METK_VIBPA ;  B7VKB3, METK_VIBSL ;  Q8DCA3, METK_VIBVU ;
DR   Q7MHK6, METK_VIBVY ;  B0LXM0, METK_WHEAT ;  Q8D2N8, METK_WIGBR ;
DR   Q7M7Z2, METK_WOLSU ;  Q8PP75, METK_XANAC ;  Q3BXB7, METK_XANC5 ;
DR   Q4UR08, METK_XANC8 ;  B0RV66, METK_XANCB ;  Q8PCH3, METK_XANCP ;
DR   Q2NZF1, METK_XANOM ;  B2SPP5, METK_XANOP ;  Q5GW76, METK_XANOR ;
DR   B2I898, METK_XYLF2 ;  Q9PGB0, METK_XYLFA ;  B0U4E7, METK_XYLFM ;
DR   Q87AY6, METK_XYLFT ;  A1JPS4, METK_YERE8 ;  A7FEZ7, METK_YERP3 ;
DR   Q1CB69, METK_YERPA ;  B2K0S7, METK_YERPB ;  Q8ZHG7, METK_YERPE ;
DR   A9R314, METK_YERPG ;  Q1CEX6, METK_YERPN ;  A4TI83, METK_YERPP ;
DR   Q666P5, METK_YERPS ;  B1JNQ2, METK_YERPY ;  Q5NQV7, METK_ZYMMO ;
DR   O67275, METL_AQUAE ;
//
ID   2.5.1.7
DE   UDP-N-acetylglucosamine 1-carboxyvinyltransferase.
AN   Enoylpyruvate transferase.
AN   MurA transferase.
AN   Phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase.
AN   Phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-
AN   carboxyethyltransferase.
AN   Phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine
AN   enolpyruvyltransferase.
AN   Phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose
AN   3-enolpyruvyltransferase.
AN   Phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase.
AN   Pyruvate-UDP-acetylglucosamine transferase.
AN   Pyruvate-uridine diphospho-N-acetyl-glucosamine transferase.
AN   Pyruvate-uridine diphospho-N-acetylglucosamine transferase.
AN   Pyruvic-uridine diphospho-N-acetylglucosaminyltransferase.
AN   UDP-N-acetylglucosamine 1-carboxyvinyl-transferase.
AN   UDP-N-acetylglucosamine enoylpyruvyltransferase.
CA   Phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine = phosphate + UDP-N-
CA   acetyl-3-O-(1-carboxyvinyl)-D-glucosamine.
DR   Q81K13, MURA1_BACAN;  Q72XG6, MURA1_BACC1;  Q814X9, MURA1_BACCR;
DR   Q630W1, MURA1_BACCZ;  Q9K6I0, MURA1_BACHD;  Q6HAZ8, MURA1_BACHK;
DR   Q65DX8, MURA1_BACLD;  Q5WB82, MURA1_BACSK;  P70965, MURA1_BACSU;
DR   Q3AAE9, MURA1_CARHZ;  Q97F79, MURA1_CLOAB;  Q8XID7, MURA1_CLOPE;
DR   Q899K4, MURA1_CLOTE;  Q836E5, MURA1_ENTFA;  Q5KUL0, MURA1_GEOKA;
DR   Q9CI17, MURA1_LACLA;  Q88UU5, MURA1_LACPL;  Q38WK8, MURA1_LACSS;
DR   Q5WYX3, MURA1_LEGPL;  Q927W7, MURA1_LISIN;  Q71WQ2, MURA1_LISMF;
DR   Q8Y4C4, MURA1_LISMO;  Q8EM86, MURA1_OCEIH;  Q7VAT0, MURA1_PROMA;
DR   Q989E5, MURA1_RHILO;  Q2YUK4, MURA1_STAAB;  Q5HEA0, MURA1_STAAC;
DR   Q931H5, MURA1_STAAM;  P84058, MURA1_STAAN;  Q6GEX5, MURA1_STAAR;
DR   Q6G7L0, MURA1_STAAS;  P84059, MURA1_STAAW;  Q5HMC2, MURA1_STAEQ;
DR   Q8CRN6, MURA1_STAES;  Q4L805, MURA1_STAHJ;  Q49Z71, MURA1_STAS1;
DR   Q3K1L5, MURA1_STRA1;  Q8E5W8, MURA1_STRA3;  Q8E091, MURA1_STRA5;
DR   Q8DT57, MURA1_STRMU;  P65458, MURA1_STRP1;  P0DC44, MURA1_STRP3;
DR   Q5XCX7, MURA1_STRP6;  P65459, MURA1_STRP8;  Q48UD0, MURA1_STRPM;
DR   Q97NQ4, MURA1_STRPN;  P0DC45, MURA1_STRPQ;  Q8DNE8, MURA1_STRR6;
DR   Q5LZI4, MURA1_STRT1;  Q5M439, MURA1_STRT2;  Q67Q46, MURA1_SYMTH;
DR   Q8RD88, MURA1_THETN;  Q81JW5, MURA2_BACAN;  Q72XB5, MURA2_BACC1;
DR   Q814T6, MURA2_BACCR;  Q630R4, MURA2_BACCZ;  Q9K6E5, MURA2_BACHD;
DR   Q6HAU9, MURA2_BACHK;  Q65DU2, MURA2_BACLD;  Q5WB48, MURA2_BACSK;
DR   P19670, MURA2_BACSU;  Q3A949, MURA2_CARHZ;  Q97DD9, MURA2_CLOAB;
DR   Q8XH79, MURA2_CLOPE;  Q898X3, MURA2_CLOTE;  Q831A8, MURA2_ENTFA;
DR   Q5KUG7, MURA2_GEOKA;  Q9CIP4, MURA2_LACLA;  Q88Z54, MURA2_LACPL;
DR   Q38V49, MURA2_LACSS;  Q5WY61, MURA2_LEGPL;  Q927U1, MURA2_LISIN;
DR   Q71WM7, MURA2_LISMF;  Q8Y4A2, MURA2_LISMO;  Q8EM55, MURA2_OCEIH;
DR   Q7VAC5, MURA2_PROMA;  Q986Q6, MURA2_RHILO;  Q2YUM9, MURA2_STAAB;
DR   Q5HE76, MURA2_STAAC;  P65456, MURA2_STAAM;  P65457, MURA2_STAAN;
DR   Q6GEV1, MURA2_STAAR;  Q6G7I6, MURA2_STAAS;  Q8NVG3, MURA2_STAAW;
DR   Q5HM98, MURA2_STAEQ;  Q8CRM7, MURA2_STAES;  Q4L7Y1, MURA2_STAHJ;
DR   Q49Z47, MURA2_STAS1;  Q3K1J2, MURA2_STRA1;  Q8E5U6, MURA2_STRA3;
DR   Q8E069, MURA2_STRA5;  Q8DT24, MURA2_STRMU;  Q99Z78, MURA2_STRP1;
DR   P0DC46, MURA2_STRP3;  Q5XBJ7, MURA2_STRP6;  Q8P0G7, MURA2_STRP8;
DR   Q48SU8, MURA2_STRPM;  Q97QW6, MURA2_STRPN;  P0DC47, MURA2_STRPQ;
DR   Q8DPV4, MURA2_STRR6;  Q5LYL3, MURA2_STRT1;  Q5M376, MURA2_STRT2;
DR   Q67KA0, MURA2_SYMTH;  Q8R9G7, MURA2_THETN;  Q67J65, MURA3_SYMTH;
DR   Q8R6V0, MURA3_THETN;  A1TKY2, MURA_ACIAC ;  Q6FED0, MURA_ACIAD ;
DR   Q1IPU1, MURA_ACIBL ;  C1F8M5, MURA_ACIC5 ;  A5FYN4, MURA_ACICJ ;
DR   B9MDV0, MURA_ACIET ;  B7JA12, MURA_ACIF2 ;  B5EQE5, MURA_ACIF5 ;
DR   P33986, MURA_ACIGB ;  A3N1T6, MURA_ACTP2 ;  B3H259, MURA_ACTP7 ;
DR   B0BQM0, MURA_ACTPJ ;  A6VMG5, MURA_ACTSZ ;  A0KQ23, MURA_AERHH ;
DR   A4SHW5, MURA_AERS4 ;  Q8UHW9, MURA_AGRT5 ;  B9JR47, MURA_AGRVS ;
DR   B2UNJ3, MURA_AKKM8 ;  Q0VS40, MURA_ALCBS ;  Q0A6H8, MURA_ALHEH ;
DR   B6EMB5, MURA_ALISL ;  B4RWE6, MURA_ALTMD ;  B8JAU0, MURA_ANAD2 ;
DR   Q2IMV5, MURA_ANADE ;  A7HI47, MURA_ANADF ;  B9KHN2, MURA_ANAMF ;
DR   Q5PBP4, MURA_ANAMM ;  B4UAY6, MURA_ANASK ;  Q3MD78, MURA_ANAVT ;
DR   O67315, MURA_AQUAE ;  A8EVW0, MURA_ARCB4 ;  Q5P787, MURA_AROAE ;
DR   A8IC24, MURA_AZOC5 ;  C1DQ65, MURA_AZOVD ;  Q5L9P3, MURA_BACFN ;
DR   Q64PY6, MURA_BACFR ;  Q8A681, MURA_BACTN ;  Q6G226, MURA_BARHE ;
DR   Q6FYT1, MURA_BARQU ;  A9IXV7, MURA_BART1 ;  Q1LU57, MURA_BAUCH ;
DR   Q6MRK7, MURA_BDEBA ;  B2IJH9, MURA_BEII9 ;  Q7VQS0, MURA_BLOFL ;
DR   Q493Y9, MURA_BLOPB ;  Q2KTT8, MURA_BORA1 ;  Q7WDY6, MURA_BORBR ;
DR   O51428, MURA_BORBU ;  Q661E8, MURA_BORGA ;  Q7W2Y6, MURA_BORPA ;
DR   A9HWD9, MURA_BORPD ;  Q7VSZ3, MURA_BORPE ;  Q89W71, MURA_BRAJA ;
DR   B2S906, MURA_BRUA1 ;  Q2YPB6, MURA_BRUA2 ;  Q57F97, MURA_BRUAB ;
DR   A9M7U1, MURA_BRUC2 ;  C0RGX7, MURA_BRUMB ;  P65452, MURA_BRUME ;
DR   A5VNK4, MURA_BRUO2 ;  B0CJN2, MURA_BRUSI ;  P65453, MURA_BRUSU ;
DR   B8D9G9, MURA_BUCA5 ;  P57466, MURA_BUCAI ;  Q8K9G4, MURA_BUCAP ;
DR   B8D7S1, MURA_BUCAT ;  Q89AE9, MURA_BUCBP ;  Q62GD7, MURA_BURMA ;
DR   Q3JMZ4, MURA_BURP1 ;  B2JHY7, MURA_BURP8 ;  B2SZ71, MURA_BURPP ;
DR   Q63Q84, MURA_BURPS ;  Q39K93, MURA_BURS3 ;  Q13TQ2, MURA_BURXL ;
DR   A0RPC8, MURA_CAMFF ;  A7I1U0, MURA_CAMHC ;  A8FLR7, MURA_CAMJ8 ;
DR   A7H3N6, MURA_CAMJD ;  Q9PP65, MURA_CAMJE ;  A1VZK1, MURA_CAMJJ ;
DR   Q5HUT8, MURA_CAMJR ;  B9KG80, MURA_CAMLR ;  B8GZB1, MURA_CAUCN ;
DR   Q9A5U7, MURA_CAUCR ;  B0T791, MURA_CAUSK ;  B3PBY5, MURA_CELJU ;
DR   Q5L6U5, MURA_CHLAB ;  Q3AR32, MURA_CHLCH ;  B3EGH6, MURA_CHLL2 ;
DR   Q9PJT7, MURA_CHLMU ;  B3QM48, MURA_CHLP8 ;  A1BEN1, MURA_CHLPD ;
DR   Q9Z7Y2, MURA_CHLPN ;  B3QX75, MURA_CHLT3 ;  Q3KLP3, MURA_CHLTA ;
DR   Q8KEX7, MURA_CHLTE ;  O84461, MURA_CHLTR ;  Q7P0X5, MURA_CHRVO ;
DR   A8AQ80, MURA_CITK8 ;  A7FZC7, MURA_CLOB1 ;  Q47VJ4, MURA_COLP3 ;
DR   B5Y8H0, MURA_COPPD ;  Q6NFK1, MURA_CORDI ;  Q8FMR0, MURA_COREF ;
DR   Q8NML5, MURA_CORGL ;  Q4JXA4, MURA_CORJK ;  B6J8R8, MURA_COXB1 ;
DR   B6J0U7, MURA_COXB2 ;  A9KDT8, MURA_COXBN ;  A9NDE8, MURA_COXBR ;
DR   Q83DI0, MURA_COXBU ;  Q0K685, MURA_CUPNH ;  Q46WL0, MURA_CUPPJ ;
DR   B3R7A2, MURA_CUPTR ;  Q47AK9, MURA_DECAR ;  C1CX71, MURA_DEIDV ;
DR   Q1IYK3, MURA_DEIGD ;  Q9RVA6, MURA_DEIRA ;  A9BX80, MURA_DELAS ;
DR   B8FKV1, MURA_DESAA ;  C6BW35, MURA_DESAD ;  C0QDM7, MURA_DESAH ;
DR   B8J283, MURA_DESDA ;  Q315P9, MURA_DESDG ;  C4XR49, MURA_DESMR ;
DR   A8ZWM4, MURA_DESOH ;  Q6AJM7, MURA_DESPS ;  Q9ZH21, MURA_DESTE ;
DR   Q726D3, MURA_DESVH ;  B8DMV2, MURA_DESVM ;  A1V9N9, MURA_DESVV ;
DR   A5EYD6, MURA_DICNV ;  A8LS12, MURA_DINSH ;  A7ZS86, MURA_ECO24 ;
DR   B7UJS9, MURA_ECO27 ;  B7MBV8, MURA_ECO45 ;  B7LHP8, MURA_ECO55 ;
DR   Q8X9J9, MURA_ECO57 ;  B5YS78, MURA_ECO5E ;  B7NKQ6, MURA_ECO7I ;
DR   B7N0X1, MURA_ECO81 ;  B7M095, MURA_ECO8A ;  C4ZSS8, MURA_ECOBW ;
DR   A8A504, MURA_ECOHS ;  A1AG91, MURA_ECOK1 ;  Q0TCS1, MURA_ECOL5 ;
DR   P0A750, MURA_ECOL6 ;  B1IQT4, MURA_ECOLC ;  P0A749, MURA_ECOLI ;
DR   B7NDH3, MURA_ECOLU ;  B6I1R2, MURA_ECOSE ;  B1LGF5, MURA_ECOSM ;
DR   Q1R6E7, MURA_ECOUT ;  B2KDP9, MURA_ELUMP ;  A4WF02, MURA_ENT38 ;
DR   P33038, MURA_ENTCC ;  A7MNS2, MURA_ENTS8 ;  Q6DAF2, MURA_ERWCT ;
DR   B2VGU0, MURA_ERWT9 ;  B7LR56, MURA_ESCF3 ;  A7HN55, MURA_FERNB ;
DR   B0S3H8, MURA_FINM2 ;  Q8RIQ1, MURA_FUSNN ;  B3E4X8, MURA_GEOLS ;
DR   Q39YP9, MURA_GEOMG ;  B9M0L4, MURA_GEOSF ;  Q748B3, MURA_GEOSL ;
DR   A5G8T5, MURA_GEOUR ;  Q7NGP3, MURA_GLOVI ;  A9HFN0, MURA_GLUDA ;
DR   Q5FSM2, MURA_GLUOX ;  Q0BTB8, MURA_GRABC ;  Q7VP51, MURA_HAEDU ;
DR   Q4QLK7, MURA_HAEI8 ;  A5UD24, MURA_HAEIE ;  A5UIK7, MURA_HAEIG ;
DR   P45025, MURA_HAEIN ;  B8F4Y1, MURA_HAEPS ;  Q0I3X9, MURA_HAES1 ;
DR   B0UUW1, MURA_HAES2 ;  Q2SBJ4, MURA_HAHCH ;  A1WYW6, MURA_HALHL ;
DR   B8CZ07, MURA_HALOH ;  C4K7J9, MURA_HAMD5 ;  Q17WZ6, MURA_HELAH ;
DR   Q7VIM8, MURA_HELHP ;  B6JLN6, MURA_HELP2 ;  B5Z721, MURA_HELPG ;
DR   Q1CTM2, MURA_HELPH ;  Q9ZLI6, MURA_HELPJ ;  B2UTH9, MURA_HELPS ;
DR   P56189, MURA_HELPY ;  A4G9J3, MURA_HERAR ;  Q0C2I2, MURA_HYPNA ;
DR   Q5R0J5, MURA_IDILO ;  A6T383, MURA_JANMA ;  Q28NA9, MURA_JANSC ;
DR   B5XSV2, MURA_KLEP3 ;  A6TEK8, MURA_KLEP7 ;  C5CFW2, MURA_KOSOT ;
DR   Q5FME5, MURA_LACAC ;  Q74LG1, MURA_LACJO ;  C1DBX7, MURA_LARHH ;
DR   Q1MQ35, MURA_LAWIP ;  Q5X6Q6, MURA_LEGPA ;  Q5ZX85, MURA_LEGPH ;
DR   B1XX71, MURA_LEPCP ;  Q2W5T9, MURA_MAGSA ;  A0L6Y9, MURA_MAGSM ;
DR   Q65RU6, MURA_MANSM ;  A1U459, MURA_MARAV ;  Q0AQL8, MURA_MARMM ;
DR   Q11LX8, MURA_MESSB ;  B7KYA2, MURA_METC4 ;  Q606Q0, MURA_METCA ;
DR   A9W480, MURA_METEP ;  Q1H4S0, MURA_METFK ;  B3DYW2, MURA_METI4 ;
DR   B8IH95, MURA_METNO ;  B1ZKB3, MURA_METPB ;  B1LUQ0, MURA_METRJ ;
DR   B0UL80, MURA_METS4 ;  B8ESQ9, MURA_METSB ;  O32849, MURA_MYCA9 ;
DR   P0A5L3, MURA_MYCBO ;  O32857, MURA_MYCCH ;  O32858, MURA_MYCFO ;
DR   P45821, MURA_MYCLE ;  O33159, MURA_MYCNE ;  Q73X63, MURA_MYCPA ;
DR   O33160, MURA_MYCPH ;  Q59561, MURA_MYCSM ;  P0A5L2, MURA_MYCTU ;
DR   Q1D2Q7, MURA_MYXXD ;  Q5F5K6, MURA_NEIG1 ;  B4RPR2, MURA_NEIG2 ;
DR   A9LZI5, MURA_NEIM0 ;  Q9JWS7, MURA_NEIMA ;  Q9K1Q9, MURA_NEIMB ;
DR   A1KWN7, MURA_NEIMF ;  Q0AFT2, MURA_NITEC ;  Q82TN2, MURA_NITEU ;
DR   Q1QRG4, MURA_NITHX ;  Q2YAN2, MURA_NITMU ;  Q3J7G9, MURA_NITOC ;
DR   A6Q3K8, MURA_NITSB ;  Q3SW27, MURA_NITWN ;  Q5Z0X7, MURA_NOCFA ;
DR   Q8Z0C4, MURA_NOSS1 ;  Q2GB76, MURA_NOVAD ;  B6JDF7, MURA_OLICO ;
DR   A5CER5, MURA_ORITB ;  B3CSG3, MURA_ORITI ;  A1B3F9, MURA_PARDP ;
DR   A7HQF9, MURA_PARL1 ;  Q6MEP6, MURA_PARUW ;  P57821, MURA_PASMU ;
DR   C6DIP6, MURA_PECCP ;  Q3A131, MURA_PELCD ;  Q3B5D7, MURA_PELLD ;
DR   B4SEZ5, MURA_PELPB ;  Q4FNE4, MURA_PELUB ;  Q7N068, MURA_PHOLL ;
DR   Q6LMC9, MURA_PHOPR ;  A1VK35, MURA_POLNA ;  B1XSU7, MURA_POLNS ;
DR   Q12FD4, MURA_POLSJ ;  A4SV13, MURA_POLSQ ;  Q7MUW1, MURA_PORGI ;
DR   B4S6J0, MURA_PROA2 ;  A3PED3, MURA_PROM0 ;  A2C466, MURA_PROM1 ;
DR   A2BY07, MURA_PROM5 ;  Q319I9, MURA_PROM9 ;  B4EXL1, MURA_PROMH ;
DR   Q7V8L0, MURA_PROMM ;  Q7V0G1, MURA_PROMP ;  A2BSM1, MURA_PROMS ;
DR   Q46JH1, MURA_PROMT ;  A4SFG7, MURA_PROVI ;  Q48EC7, MURA_PSE14 ;
DR   Q15YF4, MURA_PSEA6 ;  A6VBC3, MURA_PSEA7 ;  B7UZY9, MURA_PSEA8 ;
DR   Q02GZ1, MURA_PSEAB ;  Q9HVW7, MURA_PSEAE ;  Q1IEA0, MURA_PSEE4 ;
DR   Q4KI75, MURA_PSEF5 ;  C3K8X4, MURA_PSEFS ;  Q3IG20, MURA_PSEHT ;
DR   A4XQN4, MURA_PSEMY ;  A5VZ54, MURA_PSEP1 ;  Q3KHZ4, MURA_PSEPF ;
DR   B0KQJ3, MURA_PSEPG ;  Q88P88, MURA_PSEPK ;  Q9Z3Z6, MURA_PSEPU ;
DR   B1JBC3, MURA_PSEPW ;  Q87WV2, MURA_PSESM ;  Q4ZNV7, MURA_PSEU2 ;
DR   A4VIE0, MURA_PSEU5 ;  Q4FQF6, MURA_PSYA2 ;  Q1Q8N2, MURA_PSYCK ;
DR   A1SYM0, MURA_PSYIN ;  A5WCR5, MURA_PSYWF ;  Q1LIA4, MURA_RALME ;
DR   Q8XV78, MURA_RALSO ;  B3PNT1, MURA_RHIE6 ;  Q2KCP0, MURA_RHIEC ;
DR   Q1MLP8, MURA_RHIL3 ;  B5ZPM0, MURA_RHILW ;  Q92S27, MURA_RHIME ;
DR   C3MFX0, MURA_RHISN ;  B6INF7, MURA_RHOCS ;  Q21U98, MURA_RHOFD ;
DR   Q2IRX1, MURA_RHOP2 ;  Q07I26, MURA_RHOP5 ;  Q6N176, MURA_RHOPA ;
DR   Q20Y45, MURA_RHOPB ;  Q130J1, MURA_RHOPS ;  B3QA35, MURA_RHOPT ;
DR   Q2RQ67, MURA_RHORT ;  A3PM22, MURA_RHOS1 ;  Q3J077, MURA_RHOS4 ;
DR   A4WQ33, MURA_RHOS5 ;  B9KL51, MURA_RHOSK ;  C3PP14, MURA_RICAE ;
DR   A8GP46, MURA_RICAH ;  A8GW63, MURA_RICB8 ;  Q1RHT9, MURA_RICBR ;
DR   A8EYA6, MURA_RICCK ;  Q92H88, MURA_RICCN ;  Q4UKX7, MURA_RICFE ;
DR   A8F259, MURA_RICM5 ;  Q9ZCX3, MURA_RICPR ;  C4K1J4, MURA_RICPU ;
DR   B0BYC6, MURA_RICRO ;  A8GSV0, MURA_RICRS ;  Q68WF7, MURA_RICTY ;
DR   Q16BB7, MURA_ROSDO ;  A1AWP4, MURA_RUTMC ;  Q21FV2, MURA_SACD2 ;
DR   B5F6V8, MURA_SALA4 ;  A9MP18, MURA_SALAR ;  Q57JG1, MURA_SALCH ;
DR   B5FIN7, MURA_SALDC ;  B5R0I0, MURA_SALEP ;  B5REQ5, MURA_SALG2 ;
DR   B4TJ27, MURA_SALHS ;  B4T720, MURA_SALNS ;  Q5PLD1, MURA_SALPA ;
DR   A9N756, MURA_SALPB ;  C0PZK2, MURA_SALPC ;  B5BGL3, MURA_SALPK ;
DR   B4TWF9, MURA_SALSV ;  P65455, MURA_SALTI ;  P65454, MURA_SALTY ;
DR   A8GK08, MURA_SERP5 ;  A1SA71, MURA_SHEAM ;  B8E9M3, MURA_SHEB2 ;
DR   A3D8R8, MURA_SHEB5 ;  A6WJ66, MURA_SHEB8 ;  A9L107, MURA_SHEB9 ;
DR   Q12RY2, MURA_SHEDO ;  Q07XR4, MURA_SHEFN ;  B0TUW5, MURA_SHEHH ;
DR   A3QI66, MURA_SHELP ;  Q8EAF7, MURA_SHEON ;  A8H8M9, MURA_SHEPA ;
DR   A4Y3C4, MURA_SHEPC ;  B8CIN2, MURA_SHEPW ;  A0KT03, MURA_SHESA ;
DR   A8FR77, MURA_SHESH ;  Q0HMF2, MURA_SHESM ;  Q0HRD6, MURA_SHESR ;
DR   A1RNL3, MURA_SHESW ;  B1KII7, MURA_SHEWM ;  B2U1Y8, MURA_SHIB3 ;
DR   Q31W66, MURA_SHIBS ;  Q32BE4, MURA_SHIDS ;  Q0T095, MURA_SHIF8 ;
DR   P0A751, MURA_SHIFL ;  Q3YX52, MURA_SHISS ;  Q5LL90, MURA_SILPO ;
DR   A6U5Y5, MURA_SINMW ;  Q2NWI9, MURA_SODGM ;  Q01PT7, MURA_SOLUE ;
DR   A9GD73, MURA_SORC5 ;  Q1GVV2, MURA_SPHAL ;  A5V4L0, MURA_SPHWW ;
DR   B4SN21, MURA_STRM5 ;  B2FRX1, MURA_STRMK ;  Q30T46, MURA_SULDN ;
DR   A6Q9I6, MURA_SULNB ;  Q2LWV1, MURA_SYNAS ;  A0LJ00, MURA_SYNFM ;
DR   Q7U5R6, MURA_SYNPX ;  Q3AL98, MURA_SYNSC ;  Q55673, MURA_SYNY3 ;
DR   C5BSW4, MURA_TERTT ;  B7IDI7, MURA_THEAB ;  Q8DKS7, MURA_THEEB ;
DR   Q47KH3, MURA_THEFY ;  A8F7P0, MURA_THELT ;  Q9WXW3, MURA_THEMA ;
DR   A5IKW2, MURA_THEP1 ;  B1LA43, MURA_THESQ ;  Q72GJ4, MURA_THET2 ;
DR   Q5SM03, MURA_THET8 ;  B5YKS2, MURA_THEYD ;  Q31GZ1, MURA_THICR ;
DR   Q3SHP2, MURA_THIDA ;  B8GMK2, MURA_THISH ;  C4LCY4, MURA_TOLAT ;
DR   Q73Q03, MURA_TREDE ;  O54312, MURA_TREPA ;  B1H052, MURA_UNCTG ;
DR   C5CQI8, MURA_VARPS ;  A1WR98, MURA_VEREI ;  A5CWI9, MURA_VESOH ;
DR   A5F5B4, MURA_VIBC3 ;  Q9KP62, MURA_VIBCH ;  C3LR55, MURA_VIBCM ;
DR   Q5E7V0, MURA_VIBF1 ;  B5F9P4, MURA_VIBFM ;  A7MSC7, MURA_VIBHB ;
DR   Q87LF4, MURA_VIBPA ;  B7VKU1, MURA_VIBSL ;  Q8DEB6, MURA_VIBVU ;
DR   Q7MPA3, MURA_VIBVY ;  Q8D2M5, MURA_WIGBR ;  Q73FX6, MURA_WOLPM ;
DR   B3CLV0, MURA_WOLPP ;  Q7MAC1, MURA_WOLSU ;  Q5GRP6, MURA_WOLTR ;
DR   C0R4M1, MURA_WOLWR ;  Q8PID3, MURA_XANAC ;  Q3BQX2, MURA_XANC5 ;
DR   Q4UX36, MURA_XANC8 ;  B0RQI0, MURA_XANCB ;  Q8P719, MURA_XANCP ;
DR   Q2P682, MURA_XANOM ;  B2SJY7, MURA_XANOP ;  Q5H3C7, MURA_XANOR ;
DR   A7IK18, MURA_XANP2 ;  B2I9M4, MURA_XYLF2 ;  Q9PDG4, MURA_XYLFA ;
DR   B0U6N8, MURA_XYLFM ;  Q87DN8, MURA_XYLFT ;  A1JRA1, MURA_YERE8 ;
DR   A7FDW9, MURA_YERP3 ;  Q1C1H6, MURA_YERPA ;  B2K403, MURA_YERPB ;
DR   Q8ZB56, MURA_YERPE ;  A9R1S6, MURA_YERPG ;  Q1CE02, MURA_YERPN ;
DR   A4THI5, MURA_YERPP ;  Q665K4, MURA_YERPS ;  B1JL60, MURA_YERPY ;
DR   Q5NLR2, MURA_ZYMMO ;
//
ID   2.5.1.8
DE   Transferred entry: 2.5.1.75.
//
ID   2.5.1.9
DE   Riboflavin synthase.
CA   2 6,7-dimethyl-8-(1-D-ribityl)lumazine = riboflavin + 4-(1-D-
CA   ribitylamino)-5-amino-2,6-dihydroxypyrimidine.
PR   PROSITE; PDOC00581;
DR   Q01994, RIB1_PHOLE ;  Q93E92, RIB2_PHOLE ;  Q9UVT8, RIB4_MAGO7 ;
DR   Q9UUB1, RIB4_SCHPO ;  P50861, RIB4_YEAST ;  P50854, RISA_ACTPL ;
DR   O67604, RISA_AQUAE ;  Q44680, RISA_BACAM ;  P16440, RISA_BACSU ;
DR   P57212, RISA_BUCAI ;  Q8KA22, RISA_BUCAP ;  Q89AX1, RISA_BUCBP ;
DR   Q9PJZ1, RISA_CHLMU ;  Q9Z820, RISA_CHLPN ;  O84410, RISA_CHLTR ;
DR   P0AFU8, RISA_ECOLI ;  P45273, RISA_HAEIN ;  P65328, RISA_MYCBO ;
DR   P65327, RISA_MYCTU ;  Q01993, RISA_PHOLE ;  P51961, RISA_PHOPO ;
DR   A5DB51, RISA_PICGU ;  Q9Y7P0, RISA_SCHPO ;  P0AFU9, RISA_SHIFL ;
DR   P38145, RISA_YEAST ;  Q89K80, RISB1_BRAJA;  Q57DY1, RISB1_BRUAB;
DR   Q8YGH2, RISB1_BRUME;  Q8G1E8, RISB1_BRUSU;  Q9A9S4, RISB1_CAUCR;
DR   Q889Q6, RISB1_PSESM;  Q986N2, RISB1_RHILO;  Q92QU0, RISB1_RHIME;
DR   P61726, RISB1_RHOPA;  Q89DI7, RISB2_BRAJA;  P61711, RISB2_BRUAB;
DR   P61712, RISB2_BRUME;  P61713, RISB2_BRUSU;  Q9A8J4, RISB2_CAUCR;
DR   Q885J3, RISB2_PSESM;  Q983B0, RISB2_RHILO;  Q92NI1, RISB2_RHIME;
DR   P61727, RISB2_RHOPA;  A1TPC1, RISB_ACIAC ;  Q6F6V3, RISB_ACIAD ;
DR   B7GUW3, RISB_ACIB3 ;  B7I251, RISB_ACIB5 ;  B2I1Q0, RISB_ACIBC ;
DR   B0VPU0, RISB_ACIBS ;  A3MA34, RISB_ACIBT ;  B0V9X5, RISB_ACIBY ;
DR   A0LUD3, RISB_ACIC1 ;  B9MBL6, RISB_ACIET ;  B7J444, RISB_ACIF2 ;
DR   B5ELV8, RISB_ACIF5 ;  A1W9I3, RISB_ACISJ ;  A3MZA3, RISB_ACTP2 ;
DR   B3H0P9, RISB_ACTP7 ;  B0BTN9, RISB_ACTPJ ;  P50856, RISB_ACTPL ;
DR   A6VPE9, RISB_ACTSZ ;  Q9YC88, RISB_AERPE ;  Q8UG70, RISB_AGRT5 ;
DR   Q0ABQ4, RISB_ALHEH ;  B6EI99, RISB_ALISL ;  A6TM20, RISB_ALKMQ ;
DR   B8JEW4, RISB_ANAD2 ;  Q2ILH7, RISB_ANADE ;  A7HDY3, RISB_ANADF ;
DR   B4UIM2, RISB_ANASK ;  B9MPC6, RISB_ANATD ;  Q3MCG0, RISB_ANAVT ;
DR   B7GKI1, RISB_ANOFW ;  O66529, RISB_AQUAE ;  Q8GLK5, RISB_AQUPY ;
DR   O80575, RISB_ARATH ;  A8EVW3, RISB_ARCB4 ;  O28152, RISB_ARCFU ;
DR   Q5P3H3, RISB_AROAE ;  A1R5R8, RISB_ARTAT ;  B8H6T9, RISB_ARTCA ;
DR   A0JVK2, RISB_ARTS2 ;  A8I0J5, RISB_AZOC5 ;  A1K280, RISB_AZOSB ;
DR   C1DLH8, RISB_AZOVD ;  A7Z674, RISB_BACA2 ;  C3P7P8, RISB_BACAA ;
DR   C3LIX8, RISB_BACAC ;  A0RIB4, RISB_BACAH ;  Q44681, RISB_BACAM ;
DR   Q81MB5, RISB_BACAN ;  B7JLW7, RISB_BACC0 ;  P61719, RISB_BACC1 ;
DR   B7IWM6, RISB_BACC2 ;  C1EQY6, RISB_BACC3 ;  B7HAY5, RISB_BACC4 ;
DR   B7HNM9, RISB_BACC7 ;  B9IWX5, RISB_BACCQ ;  Q818X5, RISB_BACCR ;
DR   Q635G9, RISB_BACCZ ;  Q64XS0, RISB_BACFR ;  Q9KCL4, RISB_BACHD ;
DR   Q6HE53, RISB_BACHK ;  Q65HW7, RISB_BACLD ;  A8FER2, RISB_BACP2 ;
DR   Q5WH07, RISB_BACSK ;  P11998, RISB_BACSU ;  Q89ZW8, RISB_BACTN ;
DR   A6L3K7, RISB_BACV8 ;  A9VG51, RISB_BACWK ;  A1USI4, RISB_BARBK ;
DR   Q9REF4, RISB_BARHE ;  Q6G005, RISB_BARQU ;  A9IVC0, RISB_BART1 ;
DR   P61720, RISB_BDEBA ;  B2ICH3, RISB_BEII9 ;  B7GN04, RISB_BIFLS ;
DR   Q7VRI2, RISB_BLOFL ;  Q494E6, RISB_BLOPB ;  Q7WNT3, RISB_BORBR ;
DR   Q7W143, RISB_BORPA ;  A9I6G5, RISB_BORPD ;  Q7VTN4, RISB_BORPE ;
DR   C0QVI8, RISB_BRAHW ;  B8D9N6, RISB_BUCA5 ;  Q9ZNM0, RISB_BUCAI ;
DR   Q8K9A6, RISB_BUCAP ;  B8D7Y8, RISB_BUCAT ;  Q89AB1, RISB_BUCBP ;
DR   B1YUJ2, RISB_BURA4 ;  Q1BYB6, RISB_BURCA ;  B1JX76, RISB_BURCC ;
DR   A0K5D2, RISB_BURCH ;  B4EBT8, RISB_BURCJ ;  Q0BHJ7, RISB_BURCM ;
DR   A9AF24, RISB_BURM1 ;  A3MMR3, RISB_BURM7 ;  A2S9D4, RISB_BURM9 ;
DR   Q62HV4, RISB_BURMA ;  A1V1K5, RISB_BURMS ;  A3NY88, RISB_BURP0 ;
DR   A3NCF9, RISB_BURP6 ;  B2JED1, RISB_BURP8 ;  B2T6D0, RISB_BURPP ;
DR   Q63RP5, RISB_BURPS ;  A4JC82, RISB_BURVG ;  Q13V36, RISB_BURXL ;
DR   A4XHM5, RISB_CALS8 ;  A7ZBS6, RISB_CAMC1 ;  A7GWZ6, RISB_CAMC5 ;
DR   A0RQJ7, RISB_CAMFF ;  A7HZG0, RISB_CAMHC ;  A8FKH0, RISB_CAMJ8 ;
DR   A7H4Z4, RISB_CAMJD ;  Q9PIB9, RISB_CAMJE ;  A1VYA3, RISB_CAMJJ ;
DR   Q5HW84, RISB_CAMJR ;  B9KFN9, RISB_CAMLR ;  Q3AC30, RISB_CARHZ ;
DR   A9WFR1, RISB_CHLAA ;  Q5L4Z3, RISB_CHLAB ;  Q3AUB5, RISB_CHLCH ;
DR   Q821P5, RISB_CHLCV ;  Q255Z6, RISB_CHLFF ;  B3EHV0, RISB_CHLL2 ;
DR   Q9PLJ4, RISB_CHLMU ;  B3QL67, RISB_CHLP8 ;  B3EL33, RISB_CHLPB ;
DR   A1BJF9, RISB_CHLPD ;  Q9Z733, RISB_CHLPN ;  B9LIH3, RISB_CHLSY ;
DR   B0B8V8, RISB_CHLT2 ;  B3QWR1, RISB_CHLT3 ;  Q3KKW2, RISB_CHLTA ;
DR   B0BAI7, RISB_CHLTB ;  Q8KAW4, RISB_CHLTE ;  O84737, RISB_CHLTR ;
DR   Q7NVF3, RISB_CHRVO ;  A8AK39, RISB_CITK8 ;  A5CPK0, RISB_CLAM3 ;
DR   B0RC64, RISB_CLAMS ;  Q97LG8, RISB_CLOAB ;  A7FXC4, RISB_CLOB1 ;
DR   C3L2U0, RISB_CLOB6 ;  A6LSS9, RISB_CLOB8 ;  B2V4J4, RISB_CLOBA ;
DR   B2TJ82, RISB_CLOBB ;  A5I5U9, RISB_CLOBH ;  C1FV67, RISB_CLOBJ ;
DR   B1IL45, RISB_CLOBK ;  A7GH84, RISB_CLOBL ;  B1KZ46, RISB_CLOBM ;
DR   B8I3K7, RISB_CLOCE ;  B9E377, RISB_CLOK1 ;  A5MZ82, RISB_CLOK5 ;
DR   A0Q3H6, RISB_CLONN ;  Q0TTN7, RISB_CLOP1 ;  Q8XMW9, RISB_CLOPE ;
DR   Q0SVI9, RISB_CLOPS ;  Q897Q7, RISB_CLOTE ;  A3DBL9, RISB_CLOTH ;
DR   Q485J2, RISB_COLP3 ;  C3PG33, RISB_CORA7 ;  O24753, RISB_CORAM ;
DR   P61721, RISB_CORDI ;  Q8FT58, RISB_COREF ;  A4QEG8, RISB_CORGB ;
DR   Q8NQ53, RISB_CORGL ;  Q4JVI6, RISB_CORJK ;  C4LIS3, RISB_CORK4 ;
DR   B1VDP6, RISB_CORU7 ;  B6J943, RISB_COXB1 ;  B6J134, RISB_COXB2 ;
DR   A9KC67, RISB_COXBN ;  A9NCD4, RISB_COXBR ;  Q83DP8, RISB_COXBU ;
DR   Q0K7T9, RISB_CUPNH ;  Q474N4, RISB_CUPPJ ;  B1WW99, RISB_CYAA5 ;
DR   Q11NR0, RISB_CYTH3 ;  Q3Z799, RISB_DEHE1 ;  O68250, RISB_DEHMU ;
DR   A5FQE3, RISB_DEHSB ;  Q3ZY85, RISB_DEHSC ;  C1CYL1, RISB_DEIDV ;
DR   Q1J1M8, RISB_DEIGD ;  Q9RXZ8, RISB_DEIRA ;  B8FJ77, RISB_DESAA ;
DR   C6BYC7, RISB_DESAD ;  C0QKW7, RISB_DESAH ;  B1I2D4, RISB_DESAP ;
DR   B8J193, RISB_DESDA ;  Q30YL2, RISB_DESDG ;  B8FXB6, RISB_DESHD ;
DR   Q24WY8, RISB_DESHY ;  C4XHY9, RISB_DESMR ;  A8ZTU7, RISB_DESOH ;
DR   Q6AP94, RISB_DESPS ;  A4J6A4, RISB_DESRM ;  P61940, RISB_DESVH ;
DR   B8DJF2, RISB_DESVM ;  A1VEL0, RISB_DESVV ;  A7ZIG8, RISB_ECO24 ;
DR   B7UJN8, RISB_ECO27 ;  B7MD73, RISB_ECO45 ;  B7L649, RISB_ECO55 ;
DR   P61717, RISB_ECO57 ;  B5Z3R9, RISB_ECO5E ;  B7NJ82, RISB_ECO7I ;
DR   B7MQD0, RISB_ECO81 ;  B7M3Q4, RISB_ECO8A ;  C4ZTH2, RISB_ECOBW ;
DR   B1XF03, RISB_ECODH ;  A7ZX67, RISB_ECOHS ;  Q0TKM6, RISB_ECOL5 ;
DR   P61715, RISB_ECOL6 ;  B1J034, RISB_ECOLC ;  P61714, RISB_ECOLI ;
DR   B7N8W7, RISB_ECOLU ;  B6HZL6, RISB_ECOSE ;  B1LJG5, RISB_ECOSM ;
DR   C5BCH5, RISB_EDWI9 ;  A4W787, RISB_ENT38 ;  A7MFG5, RISB_ENTS8 ;
DR   Q6D848, RISB_ERWCT ;  B2VHS9, RISB_ERWT9 ;  Q2NAP7, RISB_ERYLH ;
DR   B7LMH2, RISB_ESCF3 ;  C4Z8N0, RISB_EUBR3 ;  B1YEJ3, RISB_EXIS2 ;
DR   A5FNH3, RISB_FLAJ1 ;  A6H143, RISB_FLAPJ ;  Q2J850, RISB_FRASC ;
DR   Q8RIR4, RISB_FUSNN ;  C1A8F6, RISB_GEMAT ;  B5E854, RISB_GEOBB ;
DR   Q5KXK7, RISB_GEOKA ;  B3E758, RISB_GEOLS ;  Q39V66, RISB_GEOMG ;
DR   B9M1E6, RISB_GEOSF ;  P61723, RISB_GEOSL ;  C6E3M5, RISB_GEOSM ;
DR   C5D3M9, RISB_GEOSW ;  A4IQG7, RISB_GEOTN ;  A5G3J9, RISB_GEOUR ;
DR   Q7NLS9, RISB_GLOVI ;  A0LZH6, RISB_GRAFK ;  Q7VM44, RISB_HAEDU ;
DR   Q4QKN2, RISB_HAEI8 ;  A5UCB8, RISB_HAEIE ;  A5UF15, RISB_HAEIG ;
DR   P45149, RISB_HAEIN ;  B8F5Z8, RISB_HAEPS ;  Q0I3N6, RISB_HAES1 ;
DR   B0UU22, RISB_HAES2 ;  Q2S9R9, RISB_HAHCH ;  A1WVG1, RISB_HALHL ;
DR   B9LUV3, RISB_HALLT ;  B0R3T7, RISB_HALS3 ;  Q9HRM5, RISB_HALSA ;
DR   Q17Z25, RISB_HELAH ;  Q7VK54, RISB_HELHP ;  B6JPA1, RISB_HELP2 ;
DR   B5Z6D8, RISB_HELPG ;  Q1CVF3, RISB_HELPH ;  Q9ZN56, RISB_HELPJ ;
DR   B2UW06, RISB_HELPS ;  O24854, RISB_HELPY ;  A9B4R4, RISB_HERA2 ;
DR   Q5QVF0, RISB_IDILO ;  Q28LT2, RISB_JANSC ;  A6WCA2, RISB_KINRD ;
DR   B5Y0X6, RISB_KLEP3 ;  A6T5E8, RISB_KLEP7 ;  B2GGU6, RISB_KOCRD ;
DR   C5CJ15, RISB_KOSOT ;  Q03PZ7, RISB_LACBA ;  Q9CGU6, RISB_LACLA ;
DR   A2RLD8, RISB_LACLM ;  Q88X16, RISB_LACPL ;  A5VJX0, RISB_LACRD ;
DR   B2G7B1, RISB_LACRJ ;  C1DB32, RISB_LARHH ;  Q1MS15, RISB_LAWIP ;
DR   Q6AGR7, RISB_LEIXX ;  B0SB77, RISB_LEPBA ;  Q04Q79, RISB_LEPBJ ;
DR   Q054N5, RISB_LEPBL ;  B0ST02, RISB_LEPBP ;  B1XYF6, RISB_LEPCP ;
DR   P61724, RISB_LEPIC ;  Q8F8T9, RISB_LEPIN ;  B1MYJ5, RISB_LEUCK ;
DR   Q03XY9, RISB_LEUMM ;  B9E7J1, RISB_MACCJ ;  Q2W4S6, RISB_MAGSA ;
DR   A0L3Z9, RISB_MAGSM ;  Q65TX7, RISB_MANSM ;  A6UTD8, RISB_META3 ;
DR   Q8TPT7, RISB_METAC ;  Q46AS9, RISB_METBF ;  B7KUS7, RISB_METC4 ;
DR   A9VYV8, RISB_METEP ;  Q1H425, RISB_METFK ;  Q57751, RISB_METJA ;
DR   Q8TYL5, RISB_METKA ;  A2SQG5, RISB_METLZ ;  A4G0E3, RISB_METM5 ;
DR   A9A8P1, RISB_METM6 ;  A6VI37, RISB_METM7 ;  Q8Q093, RISB_METMA ;
DR   A3CRJ3, RISB_METMJ ;  P61730, RISB_METMP ;  B8IPI3, RISB_METNO ;
DR   B1ZJM3, RISB_METPB ;  A2SK12, RISB_METPP ;  B1LZB2, RISB_METRJ ;
DR   A5UMS3, RISB_METS3 ;  B0UHS5, RISB_METS4 ;  A4YCS3, RISB_METS5 ;
DR   B8ENB9, RISB_METSB ;  O27443, RISB_METTH ;  A6UR43, RISB_METVS ;
DR   B0JLM0, RISB_MICAN ;  C5CBJ8, RISB_MICLC ;  Q2RK04, RISB_MOOTA ;
DR   A0QI08, RISB_MYCA1 ;  B1MCA3, RISB_MYCA9 ;  P66035, RISB_MYCBO ;
DR   A4TC12, RISB_MYCGI ;  B8ZUN3, RISB_MYCLB ;  Q9CCP3, RISB_MYCLE ;
DR   B2HP68, RISB_MYCMM ;  P61725, RISB_MYCPA ;  A3PZ89, RISB_MYCSJ ;
DR   A1UFM8, RISB_MYCSK ;  Q1B9D5, RISB_MYCSS ;  P66034, RISB_MYCTU ;
DR   A0PPL7, RISB_MYCUA ;  A1T8K2, RISB_MYCVP ;  Q1D349, RISB_MYXXD ;
DR   B9L729, RISB_NAUPA ;  Q5F9X9, RISB_NEIG1 ;  B4RJT4, RISB_NEIG2 ;
DR   A9M2W8, RISB_NEIM0 ;  P66036, RISB_NEIMA ;  P66037, RISB_NEIMB ;
DR   A1KSU7, RISB_NEIMF ;  Q0AD61, RISB_NITEC ;  Q82S08, RISB_NITEU ;
DR   Q1QMB5, RISB_NITHX ;  Q2YD51, RISB_NITMU ;  A6Q4R0, RISB_NITSB ;
DR   Q3SRV7, RISB_NITWN ;  A1SJG9, RISB_NOCSJ ;  Q8YQ43, RISB_NOSS1 ;
DR   Q2G669, RISB_NOVAD ;  Q8ELL1, RISB_OCEIH ;  B6JGI3, RISB_OLICO ;
DR   A6L8H3, RISB_PARD8 ;  Q6MCT6, RISB_PARUW ;  P57869, RISB_PASMU ;
DR   C6DB33, RISB_PECCP ;  Q03D86, RISB_PEDPA ;  Q3A4L3, RISB_PELCD ;
DR   Q3B1F0, RISB_PELLD ;  B4SGD1, RISB_PELPB ;  A1ANJ6, RISB_PELPD ;
DR   A5D1C7, RISB_PELTS ;  C0QT44, RISB_PERMH ;  Q7N0I9, RISB_PHOLL ;
DR   P51963, RISB_PHOPO ;  Q6LU12, RISB_PHOPR ;  Q6L153, RISB_PICTO ;
DR   A1VRD9, RISB_POLNA ;  B1XTA7, RISB_POLNS ;  Q129J1, RISB_POLSJ ;
DR   A4SVH2, RISB_POLSQ ;  B2RJ75, RISB_PORG3 ;  Q7MUR5, RISB_PORGI ;
DR   B4S3W8, RISB_PROA2 ;  Q6A6Y6, RISB_PROAC ;  A3PFD1, RISB_PROM0 ;
DR   A2C5A7, RISB_PROM1 ;  A8G7E8, RISB_PROM2 ;  A2C5T7, RISB_PROM3 ;
DR   A9BD87, RISB_PROM4 ;  A2BZ29, RISB_PROM5 ;  Q317Z9, RISB_PROM9 ;
DR   Q7V9M7, RISB_PROMA ;  B4EU19, RISB_PROMH ;  Q7V977, RISB_PROMM ;
DR   Q7UZL7, RISB_PROMP ;  A2BTM4, RISB_PROMS ;  Q46IE7, RISB_PROMT ;
DR   A4SGN3, RISB_PROVI ;  Q15W98, RISB_PSEA6 ;  A6V049, RISB_PSEA7 ;
DR   B7V7Q5, RISB_PSEA8 ;  Q02SM0, RISB_PSEAB ;  Q9HWX5, RISB_PSEAE ;
DR   Q1IFM0, RISB_PSEE4 ;  Q3II28, RISB_PSEHT ;  A4XZ35, RISB_PSEMY ;
DR   A5VXW0, RISB_PSEP1 ;  B0KL70, RISB_PSEPG ;  Q88QH6, RISB_PSEPK ;
DR   A4VHT4, RISB_PSEU5 ;  A1SUU5, RISB_PSYIN ;  Q8ZTE3, RISB_PYRAE ;
DR   A4WLK4, RISB_PYRAR ;  A3MX07, RISB_PYRCJ ;  Q8U4L8, RISB_PYRFU ;
DR   Q5JD31, RISB_PYRKO ;  Q1LJV9, RISB_RALME ;  B2U7F0, RISB_RALPJ ;
DR   Q8Y1H8, RISB_RALSO ;  A9WR65, RISB_RENSM ;  Q7UGV1, RISB_RHOBA ;
DR   Q53107, RISB_RHOER ;  Q21V18, RISB_RHOFD ;  Q07MT5, RISB_RHOP5 ;
DR   A1AWF3, RISB_RUTMC ;  Q21F19, RISB_SACD2 ;  A4FBK5, RISB_SACEN ;
DR   B5EXF8, RISB_SALA4 ;  A8LY39, RISB_SALAI ;  Q57SE7, RISB_SALCH ;
DR   B5FKS2, RISB_SALDC ;  B5QTG5, RISB_SALEP ;  B5R6R8, RISB_SALG2 ;
DR   B4T8Q8, RISB_SALHS ;  B4SWQ9, RISB_SALNS ;  Q5PFS8, RISB_SALPA ;
DR   C0Q7U2, RISB_SALPC ;  B5BDB5, RISB_SALPK ;  Q2S3N1, RISB_SALRD ;
DR   B4TM97, RISB_SALSV ;  P66039, RISB_SALTI ;  P66038, RISB_SALTY ;
DR   A8GAN7, RISB_SERP5 ;  A1S4C0, RISB_SHEAM ;  B8E6W6, RISB_SHEB2 ;
DR   A3D7C5, RISB_SHEB5 ;  A6WR47, RISB_SHEB8 ;  A9KYJ1, RISB_SHEB9 ;
DR   Q12Q43, RISB_SHEDO ;  Q086C4, RISB_SHEFN ;  B0TJZ0, RISB_SHEHH ;
DR   A3QC62, RISB_SHELP ;  Q8EBP3, RISB_SHEON ;  A8H1Q5, RISB_SHEPA ;
DR   A4Y961, RISB_SHEPC ;  B8CJN2, RISB_SHEPW ;  A8FSR4, RISB_SHESH ;
DR   Q0HL88, RISB_SHESM ;  Q0HXJ1, RISB_SHESR ;  A1RHD5, RISB_SHESW ;
DR   B1KJK4, RISB_SHEWM ;  B2U4L8, RISB_SHIB3 ;  Q325I6, RISB_SHIBS ;
DR   Q32JG9, RISB_SHIDS ;  P61718, RISB_SHIFL ;  Q3Z4Z4, RISB_SHISS ;
DR   Q2NV98, RISB_SODGM ;  Q01T71, RISB_SOLUE ;  Q1GNT5, RISB_SPHAL ;
DR   A5V939, RISB_SPHWW ;  Q9XH32, RISB_SPIOL ;  A7X3K7, RISB_STAA1 ;
DR   A6U2N1, RISB_STAA2 ;  Q2FFX3, RISB_STAA3 ;  Q2FXG2, RISB_STAA8 ;
DR   A5ITT7, RISB_STAA9 ;  Q2YTM0, RISB_STAAB ;  Q5HF08, RISB_STAAC ;
DR   A6QHU9, RISB_STAAE ;  P61595, RISB_STAAM ;  P99141, RISB_STAAN ;
DR   Q6GFT6, RISB_STAAR ;  Q6G8G2, RISB_STAAS ;  A8Z4J3, RISB_STAAT ;
DR   P0C600, RISB_STAAU ;  P61597, RISB_STAAW ;  B9DN29, RISB_STACT ;
DR   Q5HNE4, RISB_STAEQ ;  Q8CNU3, RISB_STAES ;  Q4L7B0, RISB_STAHJ ;
DR   A3DLT5, RISB_STAMF ;  Q49YJ6, RISB_STAS1 ;  Q3K1V6, RISB_STRA1 ;
DR   Q8E657, RISB_STRA3 ;  Q8E0I2, RISB_STRA5 ;  Q827L9, RISB_STRAW ;
DR   Q9EWJ9, RISB_STRCO ;  B1W4A5, RISB_STRGG ;  B4SJC0, RISB_STRM5 ;
DR   B2FNL3, RISB_STRMK ;  Q04MR3, RISB_STRP2 ;  B5E6C6, RISB_STRP4 ;
DR   C1CAI5, RISB_STRP7 ;  B1I8F3, RISB_STRPI ;  B8ZKD0, RISB_STRPJ ;
DR   P66040, RISB_STRPN ;  B2IS11, RISB_STRPS ;  P66041, RISB_STRR6 ;
DR   C1CBX9, RISB_STRZJ ;  C1CI69, RISB_STRZP ;  C1CP44, RISB_STRZT ;
DR   Q4JAJ2, RISB_SULAC ;  Q30TJ8, RISB_SULDN ;  C3MZ62, RISB_SULIA ;
DR   C4KIE0, RISB_SULIK ;  C3MR14, RISB_SULIL ;  C3MX02, RISB_SULIM ;
DR   C3NGF3, RISB_SULIN ;  C3N782, RISB_SULIY ;  A6QBK7, RISB_SULNB ;
DR   Q980B5, RISB_SULSO ;  B2VAC3, RISB_SULSY ;  Q975M5, RISB_SULTO ;
DR   Q2LQN1, RISB_SYNAS ;  Q31KZ5, RISB_SYNE7 ;  A0LI20, RISB_SYNFM ;
DR   B1XLJ1, RISB_SYNP2 ;  Q5N0X6, RISB_SYNP6 ;  A5GHU9, RISB_SYNPW ;
DR   Q7UA19, RISB_SYNPX ;  A5GQ24, RISB_SYNR3 ;  Q0IE03, RISB_SYNS3 ;
DR   Q3B0Q0, RISB_SYNS9 ;  Q3ANH6, RISB_SYNSC ;  P73527, RISB_SYNY3 ;
DR   C5BS85, RISB_TERTT ;  Q8DMP4, RISB_THEEB ;  Q47QZ8, RISB_THEFY ;
DR   C5A697, RISB_THEGJ ;  Q9X2E5, RISB_THEMA ;  B9K7K0, RISB_THENN ;
DR   B1Y9N5, RISB_THENV ;  B6YUQ8, RISB_THEON ;  A5ILQ1, RISB_THEP1 ;
DR   B0KAI3, RISB_THEP3 ;  B0K0Z0, RISB_THEPX ;  B1LAJ8, RISB_THESQ ;
DR   P61728, RISB_THET2 ;  Q5SLF7, RISB_THET8 ;  B5YHQ1, RISB_THEYD ;
DR   Q31FT1, RISB_THICR ;  Q3SGU9, RISB_THIDA ;  C4LAE1, RISB_TOLAT ;
DR   Q83HB9, RISB_TROW8 ;  Q83FM6, RISB_TROWT ;  B1H0H9, RISB_UNCTG ;
DR   A1WS77, RISB_VEREI ;  A5CWS3, RISB_VESOH ;  Q9KPU4, RISB_VIBCH ;
DR   Q5E6Z8, RISB_VIBF1 ;  Q8G9G4, RISB_VIBFI ;  B5FBF8, RISB_VIBFM ;
DR   A7MWU0, RISB_VIBHB ;  Q87RU4, RISB_VIBPA ;  Q8DF99, RISB_VIBVU ;
DR   Q7MN53, RISB_VIBVY ;  Q8D291, RISB_WIGBR ;  P61729, RISB_WOLPM ;
DR   B3CL66, RISB_WOLPP ;  Q7MAF0, RISB_WOLSU ;  Q5GT94, RISB_WOLTR ;
DR   C0R5L5, RISB_WOLWR ;  Q8PPD6, RISB_XANAC ;  Q3BXI0, RISB_XANC5 ;
DR   Q4UQU3, RISB_XANC8 ;  B0RVD2, RISB_XANCB ;  Q8PCM7, RISB_XANCP ;
DR   Q2NZ91, RISB_XANOM ;  B2SNW4, RISB_XANOP ;  A7INA7, RISB_XANP2 ;
DR   B2I8Q5, RISB_XYLF2 ;  Q9PES4, RISB_XYLFA ;  B0U4K3, RISB_XYLFM ;
DR   Q87AS7, RISB_XYLFT ;  A1JNS3, RISB_YERE8 ;  A7FLE8, RISB_YERP3 ;
DR   Q1C4I4, RISB_YERPA ;  B2K6T3, RISB_YERPB ;  Q8ZC41, RISB_YERPE ;
DR   A9R2J8, RISB_YERPG ;  Q1CL92, RISB_YERPN ;  A4TPG7, RISB_YERPP ;
DR   Q66DV8, RISB_YERPS ;  B1JIE2, RISB_YERPY ;  Q5NQA8, RISB_ZYMMO ;
DR   Q9YDC5, RISC_AERPE ;  O28856, RISC_ARCFU ;  Q58584, RISC_METJA ;
DR   O26237, RISC_METTH ;  Q59587, RISC_METTM ;
//
ID   2.5.1.10
DE   (2E,6E)-farnesyl diphosphate synthase.
AN   Farnesyl pyrophosphate synthetase.
AN   Farnesyl-diphosphate synthase.
AN   FPP synthetase.
AN   Geranyltranstransferase.
CA   Geranyl diphosphate + isopentenyl diphosphate = diphosphate + (2E,6E)-
CA   farnesyl diphosphate.
CC   -!- Some forms of this enzyme will also use dimethylallyl diphosphate as
CC       a substrate.
CC   -!- The enzyme will not accept larger prenyl diphosphates as efficient
CC       donors.
PR   PROSITE; PDOC00407;
DR   Q09152, FPPS1_ARATH;  Q7XYS9, FPPS1_ARTSI;  P49351, FPPS1_LUPAL;
DR   O24241, FPPS1_PARAR;  Q43315, FPPS2_ARATH;  Q7XYT0, FPPS2_ARTSI;
DR   P49352, FPPS2_LUPAL;  O24242, FPPS2_PARAR;  P49350, FPPS_ARTAN ;
DR   Q8WMY2, FPPS_BOVIN ;  P08836, FPPS_CHICK ;  Q92235, FPPS_GIBFU ;
DR   O64905, FPPS_HELAN ;  P14324, FPPS_HUMAN ;  P49349, FPPS_KLULA ;
DR   P49353, FPPS_MAIZE ;  Q920E5, FPPS_MOUSE ;  Q92250, FPPS_NEUCR ;
DR   P05369, FPPS_RAT   ;  O14230, FPPS_SCHPO ;  P08524, FPPS_YEAST ;
DR   Q9NH03, FPS_DICDI  ;  P34802, GGPP1_ARATH;  O04046, GGPP2_ARATH;
DR   Q9LUD9, GGPP3_ARATH;  Q9SLG2, GGPP4_ARATH;  O22043, GGPP6_ARATH;
DR   Q9ZU77, GGPP7_ARATH;  Q9LRR0, GGPP8_ARATH;  Q9LUE1, GGPP9_ARATH;
DR   Q9LJY2, GGPPA_ARATH;  Q9LIA0, GGPPB_ARATH;  Q9LHR4, GGPPC_ARATH;
DR   Q758K0, GGPPS_ASHGO;  P56966, GGPPS_BOVIN;  P80042, GGPPS_CAPAN;
DR   Q42698, GGPPS_CATRO;  Q54BK1, GGPPS_DICDI;  Q92236, GGPPS_GIBFU;
DR   Q94ID7, GGPPS_HEVBR;  O95749, GGPPS_HUMAN;  Q9WTN0, GGPPS_MOUSE;
DR   P0A5H9, GGPPS_MYCBO;  P0A5H8, GGPPS_MYCTU;  P24322, GGPPS_NEUCR;
DR   Q6F596, GGPPS_RAT  ;  Q9P885, GGPPS_RHIRA;  O59703, GGPPS_SCHPO;
DR   Q43133, GGPPS_SINAL;  Q12051, GGPPS_YEAST;  P39464, GGPS_SULAC ;
DR   P95999, GGPS_SULSO ;  Q58270, IDSA_METJA ;  O26156, IDSA_METTH ;
DR   Q53479, IDSA_METTM ;  O66952, ISPA_AQUAE ;  P54383, ISPA_BACSU ;
DR   Q45220, ISPA_BRAJA ;  P57537, ISPA_BUCAI ;  Q8K9A0, ISPA_BUCAP ;
DR   P22939, ISPA_ECOLI ;  Q08291, ISPA_GEOSE ;  P45204, ISPA_HAEIN ;
DR   O66126, ISPA_MICLU ;  P55539, ISPA_RHISN ;  Q65164, TPRT_ASFB7 ;
DR   P0C9E2, TPRT_ASFK5 ;  Q8V9T7, TPRT_ASFM2 ;  P0C9E0, TPRT_ASFP4 ;
DR   P0C9E1, TPRT_ASFWA ;  Q55EU7, Y8742_DICDI;  Q54XP1, Y8823_DICDI;
//
ID   2.5.1.11
DE   Transferred entry: 2.5.1.84 and 2.5.1.85.
//
ID   2.5.1.12
DE   Transferred entry: 2.5.1.18.
//
ID   2.5.1.13
DE   Transferred entry: 2.5.1.18.
//
ID   2.5.1.14
DE   Transferred entry: 2.5.1.18.
//
ID   2.5.1.15
DE   Dihydropteroate synthase.
AN   DHPS.
AN   Dihydropteroate diphosphorylase.
AN   Dihydropteroate pyrophosphorylase.
CA   (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate +
CA   4-aminobenzoate = diphosphate + dihydropteroate.
PR   PROSITE; PDOC00630;
PR   PROSITE; PDOC50972;
DR   P0C004, DHP1_CORGL ;  P0C002, DHP1_ECOLX ;  Q49184, DHP1_MYCFO ;
DR   P0C003, DHP1_PSEAE ;  P0AC11, DHP2_ECOLX ;  P0AC12, DHP2_SHIFL ;
DR   P0A579, DHPS1_MYCBO;  P0C0X1, DHPS1_MYCLE;  P0A578, DHPS1_MYCTU;
DR   P28822, DHPS_BACSU ;  Q05621, DHPS_CLOB8 ;  P0AC14, DHPS_ECOL6 ;
DR   P0AC13, DHPS_ECOLI ;  P43776, DHPS_HAEIN ;  Q9JT70, DHPS_NEIMA ;
DR   Q51161, DHPS_NEIMB ;  P57696, DHPS_NEIMC ;  P0AC15, DHPS_SHIFL ;
DR   Q5HIG1, DHPS_STAAC ;  P64141, DHPS_STAAM ;  P64142, DHPS_STAAN ;
DR   Q6GJF7, DHPS_STAAR ;  Q6GBX4, DHPS_STAAS ;  O05701, DHPS_STAAU ;
DR   Q8NXZ2, DHPS_STAAW ;  Q5HRP0, DHPS_STAEQ ;  Q8CMT7, DHPS_STAES ;
DR   Q59919, DHPS_STAHA ;  P0C0G1, DHPS_STRP1 ;  P0DB08, DHPS_STRP3 ;
DR   Q5XCA8, DHPS_STRP6 ;  Q8P152, DHPS_STRP8 ;  P05382, DHPS_STRPN ;
DR   P0DB09, DHPS_STRPQ ;  P0C0G0, DHPS_STRPY ;  P59655, DHPS_STRR6 ;
DR   P73248, DHPS_SYNY3 ;  Q54YD9, FOL1_DICDI ;  P29251, FOL1_PNECA ;
DR   Q4LB35, FOL1_SCHPO ;  P53848, FOL1_YEAST ;  Q821E2, FOLKP_CHLCV;
DR   P82602, FOLKP_CHLMU;  Q9Z7E8, FOLKP_CHLPN;  O84619, FOLKP_CHLTR;
//
ID   2.5.1.16
DE   Spermidine synthase.
AN   Aminopropyltransferase.
AN   Putrescine aminopropyltransferase.
CA   S-adenosylmethioninamine + putrescine = 5'-S-methyl-5'-thioadenosine +
CA   spermidine.
CC   -!- The mammalian enzyme is highly specific but the bacterial enzyme can
CC       use other acceptors and can synthesize spermine.
CC   -!- Not identical with EC 2.5.1.22.
PR   PROSITE; PDOC01033;
DR   Q9ZUB3, SPD1_ARATH ;  Q96556, SPD1_DATST ;  O48658, SPD1_HYONI ;
DR   Q9SMB1, SPD1_ORYSJ ;  Q9ZTR1, SPD1_PEA   ;  O48661, SPD2_ARATH ;
DR   Q96557, SPD2_DATST ;  O48659, SPD2_HYONI ;  Q9ZTR0, SPD2_PEA   ;
DR   O82147, SPDE_COFAR ;  O48660, SPDE_NICSY ;  Q9ZS45, SPDE_SOLLC ;
DR   O66473, SPEE1_AQUAE;  Q81JT0, SPEE1_BACAN;  Q814Q1, SPEE1_BACCR;
DR   Q8EZP1, SPEE1_LEPIN;  Q9X6R0, SPEE1_PSEAE;  Q8XQC5, SPEE1_RALSO;
DR   Q9L091, SPEE1_STRCO;  Q8RA94, SPEE1_THETN;  O67365, SPEE2_AQUAE;
DR   Q81X05, SPEE2_BACAN;  Q815E8, SPEE2_BACCR;  Q8EXA3, SPEE2_LEPIN;
DR   Q9HV34, SPEE2_PSEAE;  Q8XQC8, SPEE2_RALSO;  Q9X8S2, SPEE2_STRCO;
DR   Q8R977, SPEE2_THETN;  Q9YE02, SPEE_AERPE ;  Q0ACK7, SPEE_ALHEH ;
DR   A6TRI3, SPEE_ALKMQ ;  A8MLM9, SPEE_ALKOO ;  B9MRW0, SPEE_ANATD ;
DR   O27950, SPEE_ARCFU ;  Q72X78, SPEE_BACC1 ;  A7GVB2, SPEE_BACCN ;
DR   Q9K6B8, SPEE_BACHD ;  Q5WB31, SPEE_BACSK ;  P70998, SPEE_BACSU ;
DR   A9VSG3, SPEE_BACWK ;  Q8G4L4, SPEE_BIFLO ;  B8D908, SPEE_BUCA5 ;
DR   P57305, SPEE_BUCAI ;  Q8K9T5, SPEE_BUCAP ;  B8D7B3, SPEE_BUCAT ;
DR   A4XKM9, SPEE_CALS8 ;  Q7NQK7, SPEE_CHRVO ;  A8ALG8, SPEE_CITK8 ;
DR   Q97FX3, SPEE_CLOAB ;  A6M1N9, SPEE_CLOB8 ;  B2V328, SPEE_CLOBA ;
DR   B2TMY2, SPEE_CLOBB ;  Q18A85, SPEE_CLOD6 ;  B9E5S1, SPEE_CLOK1 ;
DR   A5N219, SPEE_CLOK5 ;  Q0TTQ7, SPEE_CLOP1 ;  Q8XMY8, SPEE_CLOPE ;
DR   A9KQ99, SPEE_CLOPH ;  Q0SVK7, SPEE_CLOPS ;  Q891W4, SPEE_CLOTE ;
DR   A3DDA0, SPEE_CLOTH ;  Q8FMF7, SPEE_COREF ;  B1I5Z0, SPEE_DESAP ;
DR   Q9XY92, SPEE_DICDI ;  A7ZHL0, SPEE_ECO24 ;  B7UIG9, SPEE_ECO27 ;
DR   B7MBA4, SPEE_ECO45 ;  B7LFY8, SPEE_ECO55 ;  P66834, SPEE_ECO57 ;
DR   B5YZF6, SPEE_ECO5E ;  B7NI81, SPEE_ECO7I ;  B7MNY3, SPEE_ECO81 ;
DR   B7M162, SPEE_ECO8A ;  C4ZRL4, SPEE_ECOBW ;  B1XC96, SPEE_ECODH ;
DR   A7ZW70, SPEE_ECOHS ;  A1A7G7, SPEE_ECOK1 ;  Q0TLL3, SPEE_ECOL5 ;
DR   P66833, SPEE_ECOL6 ;  B1IQL9, SPEE_ECOLC ;  P09158, SPEE_ECOLI ;
DR   B7N7Z1, SPEE_ECOLU ;  B6HZ96, SPEE_ECOSE ;  B1LGS2, SPEE_ECOSM ;
DR   Q1RG70, SPEE_ECOUT ;  A4W6M6, SPEE_ENT38 ;  Q6D1W4, SPEE_ERWCT ;
DR   B2VD21, SPEE_ERWT9 ;  B7LVY5, SPEE_ESCF3 ;  C4Z1Q7, SPEE_EUBE2 ;
DR   C4ZDU4, SPEE_EUBR3 ;  A1WZR2, SPEE_HALHL ;  C4K3X3, SPEE_HAMD5 ;
DR   Q17WL9, SPEE_HELAH ;  B6JM63, SPEE_HELP2 ;  B5Z7J7, SPEE_HELPG ;
DR   Q1CT37, SPEE_HELPH ;  Q9ZL11, SPEE_HELPJ ;  B2USZ6, SPEE_HELPS ;
DR   O25503, SPEE_HELPY ;  P19623, SPEE_HUMAN ;  B4U8W2, SPEE_HYDS0 ;
DR   B5Y1R1, SPEE_KLEP3 ;  A6T4R6, SPEE_KLEP7 ;  B1L5H2, SPEE_KORCO ;
DR   B0SI93, SPEE_LEPBA ;  B0STV8, SPEE_LEPBP ;  Q72V65, SPEE_LEPIC ;
DR   Q606H1, SPEE_METCA ;  Q57761, SPEE_METJA ;  Q2RHH3, SPEE_MOOTA ;
DR   Q64674, SPEE_MOUSE ;  Q7TY95, SPEE_MYCBO ;  O33279, SPEE_MYCTU ;
DR   P60593, SPEE_NEIMA ;  P60594, SPEE_NEIMB ;  Q9Y8H7, SPEE_NEUCR ;
DR   Q82XD4, SPEE_NITEU ;  Q3JDL8, SPEE_NITOC ;  Q8CV14, SPEE_OCEIH ;
DR   C6DC58, SPEE_PECCP ;  Q7N892, SPEE_PHOLL ;  Q6L1F4, SPEE_PICTO ;
DR   A3PFH4, SPEE_PROM0 ;  A2C5F4, SPEE_PROM1 ;  A8G7J0, SPEE_PROM2 ;
DR   A2CDX0, SPEE_PROM3 ;  A2BZ72, SPEE_PROM5 ;  Q317V6, SPEE_PROM9 ;
DR   Q7V9I5, SPEE_PROMA ;  Q7V3X3, SPEE_PROMM ;  Q7UZI0, SPEE_PROMP ;
DR   A2BTR7, SPEE_PROMS ;  Q46IA2, SPEE_PROMT ;  Q884N3, SPEE_PSESM ;
DR   Q9V277, SPEE_PYRAB ;  Q8ZXM4, SPEE_PYRAE ;  A4WHN0, SPEE_PYRAR ;
DR   A3MU81, SPEE_PYRCJ ;  Q8U4G1, SPEE_PYRFU ;  O57950, SPEE_PYRHO ;
DR   A1RU43, SPEE_PYRIL ;  Q5JFG9, SPEE_PYRKO ;  Q7UWD1, SPEE_RHOBA ;
DR   B5F815, SPEE_SALA4 ;  A9MPN3, SPEE_SALAR ;  Q57T89, SPEE_SALCH ;
DR   B5FIB4, SPEE_SALDC ;  B5R2R5, SPEE_SALEP ;  B5RHA5, SPEE_SALG2 ;
DR   B4TJD2, SPEE_SALHS ;  B4SU91, SPEE_SALNS ;  Q5PDA0, SPEE_SALPA ;
DR   A9MZR2, SPEE_SALPB ;  C0Q5M7, SPEE_SALPC ;  B5BL97, SPEE_SALPK ;
DR   B4TXL7, SPEE_SALSV ;  Q8Z9E2, SPEE_SALTI ;  Q8ZRS3, SPEE_SALTY ;
DR   Q09741, SPEE_SCHPO ;  A8GJ06, SPEE_SERP5 ;  Q8EAX8, SPEE_SHEON ;
DR   B2U2X0, SPEE_SHIB3 ;  Q326B5, SPEE_SHIBS ;  Q32K90, SPEE_SHIDS ;
DR   Q0T879, SPEE_SHIF8 ;  Q83MF0, SPEE_SHIFL ;  Q3Z5N9, SPEE_SHISS ;
DR   Q1GGU4, SPEE_SILST ;  Q2NVS1, SPEE_SODGM ;  Q82EU4, SPEE_STRAW ;
DR   B4SM23, SPEE_STRM5 ;  B2FKR1, SPEE_STRMK ;  P66835, SPEE_STRPN ;
DR   P66836, SPEE_STRR6 ;  B9DUY3, SPEE_STRU0 ;  Q4JAZ8, SPEE_SULAC ;
DR   C3N5P4, SPEE_SULIA ;  C4KHC0, SPEE_SULIK ;  C3MQ26, SPEE_SULIL ;
DR   C3MVE5, SPEE_SULIM ;  C3NHE1, SPEE_SULIN ;  C3NEA8, SPEE_SULIY ;
DR   Q9UXE4, SPEE_SULSO ;  Q975S5, SPEE_SULTO ;  Q31QK9, SPEE_SYNE7 ;
DR   Q2JQS1, SPEE_SYNJA ;  Q2JQ57, SPEE_SYNJB ;  Q5N3N4, SPEE_SYNP6 ;
DR   Q7U3L0, SPEE_SYNPX ;  Q0I685, SPEE_SYNS3 ;  Q9HL75, SPEE_THEAC ;
DR   Q9WZC2, SPEE_THEMA ;  B9KAY3, SPEE_THENN ;  B1YB61, SPEE_THENV ;
DR   B6YXJ9, SPEE_THEON ;  A5IJD3, SPEE_THEP1 ;  B0K9I5, SPEE_THEP3 ;
DR   B0K172, SPEE_THEPX ;  Q72K55, SPEE_THET2 ;  Q5SK28, SPEE_THET8 ;
DR   Q97BN7, SPEE_THEVO ;  B8GQ45, SPEE_THISH ;  Q8D3Q3, SPEE_VIBVU ;
DR   Q7MF74, SPEE_VIBVY ;  Q7M7Q6, SPEE_WOLSU ;  Q8PFQ4, SPEE_XANAC ;
DR   Q3BN93, SPEE_XANC5 ;  Q4UPN0, SPEE_XANC8 ;  B0RXN7, SPEE_XANCB ;
DR   Q8P447, SPEE_XANCP ;  Q2P928, SPEE_XANOM ;  B2SHF6, SPEE_XANOP ;
DR   Q5H6E7, SPEE_XANOR ;  B2I6M0, SPEE_XYLF2 ;  Q9PH03, SPEE_XYLFA ;
DR   B0U1H5, SPEE_XYLFM ;  Q87F26, SPEE_XYLFT ;  Q12074, SPEE_YEAST ;
DR   A1JJM8, SPEE_YERE8 ;  A7FM33, SPEE_YERP3 ;  Q1C3U7, SPEE_YERPA ;
DR   B2K4I2, SPEE_YERPB ;  Q8ZBJ8, SPEE_YERPE ;  A9R1H4, SPEE_YERPG ;
DR   Q1CLX1, SPEE_YERPN ;  A4TPU4, SPEE_YERPP ;  Q66EH3, SPEE_YERPS ;
DR   B1JK45, SPEE_YERPY ;
//
ID   2.5.1.17
DE   Cob(I)yrinic acid a,c-diamide adenosyltransferase.
AN   Aquacob(I)alamin adenosyltransferase.
AN   Aquocob(I)alamin vitamin B12s adenosyltransferase.
AN   ATP:cob(I)alamin Co-beta-adenosyltransferase.
AN   ATP:corrinoid adenosyltransferase.
AN   Cob(I)alamin adenosyltransferase.
CA   (1) ATP + cob(I)yrinic acid a,c-diamide = triphosphate +
CA   adenosylcob(III)yrinic acid a,c-diamide.
CA   (2) ATP + cobinamide = triphosphate + adenosylcobinamide.
CC   -!- The corrinoid adenosylation pathway comprises three steps:
CC       (1) Reduction of Co(III) to Co(II) by a one-electron transfer; this
CC       can be carried out by EC 1.16.1.3, or non-enzymically in the presence
CC       of dihydroflavin nucleotides.
CC       (2) Co(II) is reduced to Co(I) in a second single-electron transfer
CC       by EC 1.16.1.4.
CC       (3) The Co(I) conducts a nucleophilic attack on the adenosyl moiety
CC       of ATP to leave the cobalt atom in a Co(III) state (EC 2.5.1.17).
CC   -!- The enzyme responsible for the adenosylation reaction is the product
CC       of the gene cobO in the aerobic bacterium Pseudomonas denitrificans
CC       and of the gene cobA in the anaerobic bacterium Salmonella
CC       typhimurium.
CC   -!- In P.denitrificans, the enzyme shows specificity for cobyrinic acid
CC       a,c-diamide and the corrinoids that occur later in the biosynthetic
CC       pathway whereas CobA seems to have broader specificity.
CC   -!- While CobA has a preference for ATP and Mn(2+), it is able to
CC       transfer a variety of nucleosides to the cobalt, including CTP,
CC       UTP and GTP, in decreasing order of preference and to use Mg(2+)
CC       instead of Mn(2+).
DR   P0A9H6, BTUR_ECOL6 ;  P0A9H5, BTUR_ECOLI ;  P31570, BTUR_SALTY ;
DR   Q9I472, COBO_PSEAE ;  P29930, COBO_PSEDE ;  P65644, EUTT_ECOL6 ;
DR   P65643, EUTT_ECOLI ;  Q9ZFV4, EUTT_SALTY ;  Q58D49, MMAB_BOVIN ;
DR   Q96EY8, MMAB_HUMAN ;  Q9D273, MMAB_MOUSE ;  O34899, PDUO_BACSU ;
DR   P45515, PDUO_CITFR ;  P64804, PDUO_MYCBO ;  P53523, PDUO_MYCLE ;
DR   P64803, PDUO_MYCTU ;
//
ID   2.5.1.18
DE   Glutathione transferase.
AN   Glutathione S-alkyltransferase.
AN   Glutathione S-aralkyltransferase.
AN   Glutathione S-aryltransferase.
AN   S-(hydroxyalkyl)glutathione lyase.
CA   RX + glutathione = HX + R-S-glutathione.
CC   -!- A group of enzymes of broad specificity.
CC   -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a
CC       sulfate, nitrile or halide group.
CC   -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to
CC       glutathione, the reduction of polyol nitrate by glutathione to polyol
CC       and nitrile, certain isomerization reactions and disulfide
CC       interchange.
CC   -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and
CC       EC 4.4.1.7.
DR   Q9FWR4, DHAR1_ARATH;  Q9FRL8, DHAR2_ARATH;  Q8LE52, DHAR3_ARATH;
DR   Q9FG59, DHAR4_ARATH;  Q8L7C9, FINP1_ARATH;  Q9I4K6, FOSA_PSEAE ;
DR   Q56415, FOSA_SERMA ;  Q9SRY5, GST11_ARATH;  Q9SLM6, GST16_ARATH;
DR   O77462, GST1A_ANOGA;  O77473, GST1B_ANOGA;  Q93112, GST1C_ANOGA;
DR   Q93113, GST1D_ANOGA;  P46436, GST1_ASCSU ;  O18598, GST1_BLAGE ;
DR   P41043, GST1_DROME ;  P46434, GST1_ONCVO ;  Q9Y7Q2, GST1_SCHPO ;
DR   P40582, GST1_YEAST ;  Q9FQA3, GST23_MAIZE;  P30112, GST26_FASHE;
DR   P08515, GST26_SCHJA;  P15964, GST26_SCHMA;  P31670, GST27_FASHE;
DR   P35661, GST27_SCHMA;  P31671, GST28_FASHE;  P30113, GST28_SCHBO;
DR   P30114, GST28_SCHHA;  P26624, GST28_SCHJA;  P09792, GST28_SCHMA;
DR   P56598, GST29_FASHE;  P48429, GST2_ASCSU ;  O16115, GST2_CAEEL ;
DR   P0CG29, GST2_HUMAN ;  P46429, GST2_MANSE ;  O59827, GST2_SCHPO ;
DR   Q12390, GST2_YEAST ;  Q09607, GST36_CAEEL;  O16116, GST3_CAEEL ;
DR   Q9P6M1, GST3_SCHPO ;  Q21355, GST4_CAEEL ;  Q09596, GST5_CAEEL ;
DR   P20137, GST5_CHICK ;  P82607, GST67_DICLA;  P91252, GST6_CAEEL ;
DR   P91253, GST7_CAEEL ;  P82608, GST82_DICLA;  P91254, GST8_CAEEL ;
DR   Q21743, GST9_CAEEL ;  P80894, GSTA1_ANTST;  Q28035, GSTA1_BOVIN;
DR   P81706, GSTA1_CAVPO;  Q08392, GSTA1_CHICK;  Q55FF3, GSTA1_DICDI;
DR   P08263, GSTA1_HUMAN;  P13745, GSTA1_MOUSE;  P51781, GSTA1_PIG  ;
DR   Q08863, GSTA1_RABIT;  P00502, GSTA1_RAT  ;  O18879, GSTA2_BOVIN;
DR   Q08393, GSTA2_CHICK;  Q556G3, GSTA2_DICDI;  P09210, GSTA2_HUMAN;
DR   P10648, GSTA2_MOUSE;  P04903, GSTA2_RAT  ;  P26697, GSTA3_CHICK;
DR   Q54VI4, GSTA3_DICDI;  Q16772, GSTA3_HUMAN;  P30115, GSTA3_MOUSE;
DR   P04904, GSTA3_RAT  ;  Q5E9G0, GSTA4_BOVIN;  Q86AU1, GSTA4_DICDI;
DR   O15217, GSTA4_HUMAN;  P24472, GSTA4_MOUSE;  P14942, GSTA4_RAT  ;
DR   Q54QV7, GSTA5_DICDI;  Q7RTV2, GSTA5_HUMAN;  P46418, GSTA5_RAT  ;
DR   Q6AXY0, GSTA6_RAT  ;  P30568, GSTA_PLEPL ;  Q08862, GSTA_RABIT ;
DR   P82999, GSTE1_PSEUO;  P83000, GSTE2_PSEUO;  P83001, GSTE_PSEFL ;
DR   P82998, GSTE_PSEP1 ;  P82996, GSTE_PSEPU ;  P82997, GSTE_PSEUF ;
DR   P42760, GSTF1_ARATH;  P12653, GSTF1_MAIZE;  O65857, GSTF1_ORYSJ;
DR   P84983, GSTF1_POPEU;  P30109, GSTF1_TOBAC;  P30110, GSTF1_WHEAT;
DR   O82451, GSTF2_ORYSJ;  P84984, GSTF2_POPEU;  P46440, GSTF2_TOBAC;
DR   P30111, GSTF2_WHEAT;  P42761, GSTF3_ARATH;  P04907, GSTF3_MAIZE;
DR   P46422, GSTF4_ARATH;  P46420, GSTF4_MAIZE;  P42769, GSTF5_ARATH;
DR   Q96266, GSTF6_ARATH;  Q96324, GSTF7_ARATH;  P48438, GSTF_BRAOT ;
DR   P46423, GSTF_HYOMU ;  Q04522, GSTF_SILCU ;  Q09652, GSTK1_CAEEL;
DR   Q9Y2Q3, GSTK1_HUMAN;  Q9DCM2, GSTK1_MOUSE;  P24473, GSTK1_RAT  ;
DR   Q18973, GSTK2_CAEEL;  Q9N0V4, GSTM1_BOVIN;  P46419, GSTM1_DERPT;
DR   P09488, GSTM1_HUMAN;  Q9TSM5, GSTM1_MACFA;  P10649, GSTM1_MOUSE;
DR   P04905, GSTM1_RAT  ;  P20136, GSTM2_CHICK;  P28161, GSTM2_HUMAN;
DR   Q9TSM4, GSTM2_MACFA;  Q9BEB0, GSTM2_MACFU;  P15626, GSTM2_MOUSE;
DR   Q5R8E8, GSTM2_PONAB;  P08010, GSTM2_RAT  ;  P21266, GSTM3_HUMAN;
DR   Q9BEA9, GSTM3_MACFU;  Q03013, GSTM4_HUMAN;  P19639, GSTM4_MOUSE;
DR   P08009, GSTM4_RAT  ;  P46439, GSTM5_HUMAN;  P86214, GSTM5_MESAU;
DR   P48774, GSTM5_MOUSE;  Q9Z1B2, GSTM5_RAT  ;  O35660, GSTM6_MOUSE;
DR   Q80W21, GSTM7_MOUSE;  P16413, GSTMU_CAVPO;  Q00285, GSTMU_CRILO;
DR   P30116, GSTMU_MESAU;  P46409, GSTMU_RABIT;  P34345, GSTO1_CAEEL;
DR   P78417, GSTO1_HUMAN;  O09131, GSTO1_MOUSE;  Q9N1F5, GSTO1_PIG  ;
DR   Q9Z339, GSTO1_RAT  ;  A8XT16, GSTO2_CAEBR;  P34277, GSTO2_CAEEL;
DR   Q9H4Y5, GSTO2_HUMAN;  Q8K2Q2, GSTO2_MOUSE;  Q6AXV9, GSTO2_RAT  ;
DR   P81124, GSTO_APLCA ;  P28801, GSTP1_BOVIN;  P81942, GSTP1_BUFBU;
DR   P10299, GSTP1_CAEEL;  Q9TTY8, GSTP1_CAPHI;  P46424, GSTP1_CRILO;
DR   P47954, GSTP1_CRIMI;  P09211, GSTP1_HUMAN;  Q28514, GSTP1_MACMU;
DR   Q60550, GSTP1_MESAU;  P19157, GSTP1_MOUSE;  P80031, GSTP1_PIG  ;
DR   Q5R8R5, GSTP1_PONAB;  P04906, GSTP1_RAT  ;  Q8JFZ2, GSTP1_XENLA;
DR   P83325, GSTP2_BUFBU;  P46425, GSTP2_MOUSE;  Q9N4X8, GSTPA_CAEEL;
DR   P46426, GSTP_DIRIM ;  P46427, GSTP_ONCVO ;  Q2NL00, GSTT1_BOVIN;
DR   P20135, GSTT1_CHICK;  P30104, GSTT1_DROER;  P67804, GSTT1_DROMA;
DR   P20432, GSTT1_DROME;  P30106, GSTT1_DROSE;  P67805, GSTT1_DROSI;
DR   P30107, GSTT1_DROTE;  P30108, GSTT1_DROYA;  P30711, GSTT1_HUMAN;
DR   P42860, GSTT1_LUCCU;  P46430, GSTT1_MANSE;  Q64471, GSTT1_MOUSE;
DR   P28338, GSTT1_MUSDO;  Q01579, GSTT1_RAT  ;  Q94999, GSTT2_ANOGA;
DR   Q9VG98, GSTT2_DROME;  P0CG30, GSTT2_HUMAN;  Q61133, GSTT2_MOUSE;
DR   P46431, GSTT2_MUSDO;  P30713, GSTT2_RAT  ;  Q9VG97, GSTT3_DROME;
DR   P46432, GSTT3_MUSDO;  Q9VG96, GSTT4_DROME;  A8MPT4, GSTT4_HUMAN;
DR   Q9D4P7, GSTT4_MOUSE;  P46433, GSTT4_MUSDO;  Q4V8E6, GSTT4_RAT  ;
DR   Q9VG95, GSTT5_DROME;  Q9VG94, GSTT6_DROME;  O76483, GSTT7_ANOGA;
DR   Q9VG93, GSTT7_DROME;  A2XMN2, GSTU1_ORYSI;  Q10CE7, GSTU1_ORYSJ;
DR   Q06398, GSTU6_ORYSJ;  P50471, GSTX1_NICPL;  P32111, GSTX1_SOLTU;
DR   Q03662, GSTX1_TOBAC;  P50472, GSTX2_MAIZE;  Q03663, GSTX2_TOBAC;
DR   P46417, GSTX3_SOYBN;  Q03664, GSTX3_TOBAC;  Q03666, GSTX4_TOBAC;
DR   P32110, GSTX6_SOYBN;  P46421, GSTXA_ARATH;  P25317, GSTXA_TOBAC;
DR   P49332, GSTXC_TOBAC;  P30102, GSTY2_ISSOR;  Q9ZVQ3, GSTZ1_ARATH;
DR   P28342, GSTZ1_DIACA;  Q9ZVQ4, GSTZ2_ARATH;  Q03425, GSTZ2_DIACA;
DR   P57108, GSTZ_EUPES ;  O04437, GSTZ_WHEAT ;  Q6R4B4, GST_ALTAL  ;
DR   P46428, GST_ANOGA  ;  P83246, GST_ASADI  ;  D2YW48, GST_COCIM  ;
DR   P0A9D3, GST_ECO57  ;  P0A9D2, GST_ECOLI  ;  P44521, GST_HAEIN  ;
DR   P46437, GST_MUSDO  ;  P81065, GST_OCHAN  ;  P46088, GST_OMMSL  ;
DR   Q8ILQ7, GST_PLAF7  ;  Q8MU52, GST_PLAFA  ;  Q0ZS46, GST_PLAVI  ;
DR   Q7REH6, GST_PLAYO  ;  P15214, GST_PROMI  ;  P22416, GST_SERMA  ;
DR   P45875, GST_XANCP  ;  P48239, GTO1_YEAST ;  O94524, GTO2_SCHPO ;
DR   P36156, GTO2_YEAST ;  Q04806, GTO3_YEAST ;  O73888, HPGDS_CHICK;
DR   O60760, HPGDS_HUMAN;  Q9JHF7, HPGDS_MOUSE;  O35543, HPGDS_RAT  ;
DR   O43708, MAAI_HUMAN ;  Q9WVL0, MAAI_MOUSE ;  P57113, MAAI_RAT   ;
DR   Q64L89, MGST1_BOVIN;  P10620, MGST1_HUMAN;  Q91VS7, MGST1_MOUSE;
DR   P79382, MGST1_PIG  ;  P08011, MGST1_RAT  ;  Q2KJG4, MGST2_BOVIN;
DR   Q99735, MGST2_HUMAN;  Q3T100, MGST3_BOVIN;  O14880, MGST3_HUMAN;
DR   Q9CPU4, MGST3_MOUSE;  Q54GA9, MGST_DICDI ;  O74830, YC12_SCHPO ;
//
ID   2.5.1.19
DE   3-phosphoshikimate 1-carboxyvinyltransferase.
AN   3-enol-pyruvoylshikimate-5-phosphate synthase.
AN   5-enolpyruvylshikimate-3-phosphate synthase.
AN   EPSP synthase.
CA   Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-
CA   (1-carboxyvinyl)-3-phosphoshikimate.
PR   PROSITE; PDOC00097;
DR   A5H2Q8, ARO11_LODEL;  B6QWH9, ARO11_PENMQ;  A5H2P4, ARO12_LODEL;
DR   B6QCA7, ARO12_PENMQ;  C0NL63, ARO1_AJECG ;  C6HCG7, ARO1_AJECH ;
DR   A6R8Q8, ARO1_AJECN ;  C5G8R4, ARO1_AJEDR ;  C5JKE6, ARO1_AJEDS ;
DR   C5FQ73, ARO1_ARTOC ;  Q74ZZ1, ARO1_ASHGO ;  A1CP85, ARO1_ASPCL ;
DR   B0XRM8, ARO1_ASPFC ;  B8N4Q9, ARO1_ASPFN ;  Q4WS76, ARO1_ASPFU ;
DR   Q2UCP6, ARO1_ASPOR ;  Q0D0F3, ARO1_ASPTN ;  Q5AME2, ARO1_CANAL ;
DR   B9WFG1, ARO1_CANDC ;  Q6FIV4, ARO1_CANGA ;  C5M1X2, ARO1_CANTT ;
DR   C4Y9D5, ARO1_CLAL4 ;  C5PA86, ARO1_COCP7 ;  A8NMB4, ARO1_COPC7 ;
DR   P0CM23, ARO1_CRYNB ;  P0CM22, ARO1_CRYNJ ;  P07547, ARO1_EMENI ;
DR   Q6CJC4, ARO1_KLULA ;  B0D6H2, ARO1_LACBS ;  C5DN02, ARO1_LACTC ;
DR   A4RD09, ARO1_MAGO7 ;  A8QCB2, ARO1_MALGO ;  C7YZ74, ARO1_NECH7 ;
DR   A1D244, ARO1_NEOFI ;  Q8X071, ARO1_NEUCR ;  C1H8L1, ARO1_PARBA ;
DR   C1FYJ9, ARO1_PARBD ;  C0S433, ARO1_PARBP ;  B6HAA7, ARO1_PENCW ;
DR   Q0V3H0, ARO1_PHANO ;  C4R4R8, ARO1_PICPG ;  A3LSZ2, ARO1_PICST ;
DR   Q12659, ARO1_PNECA ;  B2B223, ARO1_PODAN ;  B6JVD0, ARO1_SCHJY ;
DR   Q9P7R0, ARO1_SCHPO ;  A7F7H0, ARO1_SCLS1 ;  Q5XNP0, ARO1_SCLSC ;
DR   D1ZA70, ARO1_SORMK ;  B8M0U4, ARO1_TALSN ;  Q8J294, ARO1_THACU ;
DR   C4JYG6, ARO1_UNCRE ;  Q4P8F6, ARO1_USTMA ;  C9SE96, ARO1_VERA1 ;
DR   Q6C1X5, ARO1_YARLI ;  B3LGE9, ARO1_YEAS1 ;  C7GIN5, ARO1_YEAS2 ;
DR   A6ZY89, ARO1_YEAS7 ;  C8Z543, ARO1_YEAS8 ;  P08566, ARO1_YEAST ;
DR   C5DVG6, ARO1_ZYGRC ;  Q9KCA6, AROA1_BACHD;  Q63X54, AROA1_BURPS;
DR   Q9L213, AROA1_STRCO;  P23981, AROA1_TOBAC;  Q9K9D5, AROA2_BACHD;
DR   P39915, AROA2_BURPS;  Q9K4A7, AROA2_STRCO;  P23281, AROA2_TOBAC;
DR   B0C218, AROA_ACAM1 ;  P0A2Y5, AROA_ACHSL ;  Q1IKI5, AROA_ACIBL ;
DR   A0LS98, AROA_ACIC1 ;  A5FUH8, AROA_ACICJ ;  B7J781, AROA_ACIF2 ;
DR   B5EQ20, AROA_ACIF5 ;  A3N063, AROA_ACTP2 ;  B3GXD4, AROA_ACTP7 ;
DR   B0BNY1, AROA_ACTPJ ;  A6VMU5, AROA_ACTSZ ;  Q9YEK9, AROA_AERPE ;
DR   A4SM13, AROA_AERS4 ;  Q03321, AROA_AERSA ;  Q9R4E4, AROA_AGRSC ;
DR   B2UN97, AROA_AKKM8 ;  Q0AA54, AROA_ALHEH ;  B6EIX8, AROA_ALISL ;
DR   A6TL04, AROA_ALKMQ ;  A8MH16, AROA_ALKOO ;  B8J8W7, AROA_ANAD2 ;
DR   Q2IMC8, AROA_ANADE ;  A7H6S6, AROA_ANADF ;  B4ULJ1, AROA_ANASK ;
DR   B9MQK4, AROA_ANATD ;  Q3MAV9, AROA_ANAVT ;  O67494, AROA_AQUAE ;
DR   P05466, AROA_ARATH ;  A8EWE5, AROA_ARCB4 ;  O28775, AROA_ARCFU ;
DR   A7Z612, AROA_BACA2 ;  C3NZR4, AROA_BACAA ;  C3LF06, AROA_BACAC ;
DR   A0RFD1, AROA_BACAH ;  Q81P64, AROA_BACAN ;  B7JSV5, AROA_BACC0 ;
DR   Q736A7, AROA_BACC1 ;  B7ILG9, AROA_BACC2 ;  C1EYX7, AROA_BACC3 ;
DR   B7H636, AROA_BACC4 ;  B7HVH9, AROA_BACC7 ;  A7GN56, AROA_BACCN ;
DR   Q81C45, AROA_BACCR ;  Q63A07, AROA_BACCZ ;  Q5LHG9, AROA_BACFN ;
DR   Q64YD8, AROA_BACFR ;  Q6HHF8, AROA_BACHK ;  Q65I39, AROA_BACLD ;
DR   A8FEJ4, AROA_BACP2 ;  Q5WGR7, AROA_BACSK ;  P20691, AROA_BACSU ;
DR   Q6G545, AROA_BARHE ;  Q6G0X3, AROA_BARQU ;  A9ILL7, AROA_BART1 ;
DR   Q1LTL1, AROA_BAUCH ;  B3DSQ0, AROA_BIFLD ;  Q7VR41, AROA_BLOFL ;
DR   Q492S6, AROA_BLOPB ;  Q2L2S7, AROA_BORA1 ;  Q9RND7, AROA_BORBR ;
DR   Q7W602, AROA_BORPA ;  A9IJI7, AROA_BORPD ;  P12421, AROA_BORPE ;
DR   C0QZK3, AROA_BRAHW ;  Q89WF2, AROA_BRAJA ;  P17688, AROA_BRANA ;
DR   A5E8B1, AROA_BRASB ;  A4YJJ3, AROA_BRASO ;  C0ZCE9, AROA_BREBN ;
DR   B2S7T0, AROA_BRUA1 ;  Q2YPN6, AROA_BRUA2 ;  P0C100, AROA_BRUAB ;
DR   A9M6N0, AROA_BRUC2 ;  C0RG90, AROA_BRUMB ;  Q8YEG1, AROA_BRUME ;
DR   B0CI45, AROA_BRUSI ;  Q8G3C4, AROA_BRUSU ;  B8D9A1, AROA_BUCA5 ;
DR   P57396, AROA_BUCAI ;  Q59178, AROA_BUCAP ;  B8D7K3, AROA_BUCAT ;
DR   P59416, AROA_BUCBP ;  Q057N6, AROA_BUCCC ;  B1YV33, AROA_BURA4 ;
DR   Q1BY28, AROA_BURCA ;  B1JXR9, AROA_BURCC ;  A0K5M1, AROA_BURCH ;
DR   B4EB42, AROA_BURCJ ;  Q0BH93, AROA_BURCM ;  A9ADV6, AROA_BURM1 ;
DR   B2JF04, AROA_BURP8 ;  B2T630, AROA_BURPP ;  Q39IG1, AROA_BURS3 ;
DR   A4JCH4, AROA_BURVG ;  Q13VC2, AROA_BURXL ;  A8MB38, AROA_CALMQ ;
DR   A4XMY4, AROA_CALS8 ;  A8Z6D5, AROA_CAMC1 ;  A7GXB4, AROA_CAMC5 ;
DR   A0RQC5, AROA_CAMFF ;  A7I0N1, AROA_CAMHC ;  A8FLU4, AROA_CAMJ8 ;
DR   A7H3F2, AROA_CAMJD ;  P0C630, AROA_CAMJE ;  A1VZM9, AROA_CAMJJ ;
DR   Q5HUR3, AROA_CAMJR ;  Q3AAT7, AROA_CARHZ ;  B8H6A8, AROA_CAUCN ;
DR   Q9A2H2, AROA_CAUCR ;  B0T270, AROA_CAUSK ;  B3PJM0, AROA_CELJU ;
DR   A9WBA4, AROA_CHLAA ;  Q5L5F4, AROA_CHLAB ;  B8GC95, AROA_CHLAD ;
DR   Q3AQ41, AROA_CHLCH ;  Q822G0, AROA_CHLCV ;  Q255H3, AROA_CHLFF ;
DR   B3EGN4, AROA_CHLL2 ;  Q9PK28, AROA_CHLMU ;  B3QQU6, AROA_CHLP8 ;
DR   B3ENJ1, AROA_CHLPB ;  A1BIP2, AROA_CHLPD ;  Q9Z6M0, AROA_CHLPN ;
DR   B9LFL8, AROA_CHLSY ;  B0B7T5, AROA_CHLT2 ;  B3QZC7, AROA_CHLT3 ;
DR   Q3KLZ0, AROA_CHLTA ;  B0BC00, AROA_CHLTB ;  Q8KB71, AROA_CHLTE ;
DR   O84371, AROA_CHLTR ;  A8AIH5, AROA_CITK8 ;  Q97KM2, AROA_CLOAB ;
DR   A6M254, AROA_CLOB8 ;  B2UYK7, AROA_CLOBA ;  B2TQ51, AROA_CLOBB ;
DR   B8I5M2, AROA_CLOCE ;  Q187E3, AROA_CLOD6 ;  B9DZT0, AROA_CLOK1 ;
DR   A5N6A9, AROA_CLOK5 ;  A0Q388, AROA_CLONN ;  Q0TT99, AROA_CLOP1 ;
DR   Q8XMJ2, AROA_CLOPE ;  Q0SV34, AROA_CLOPS ;  Q894D2, AROA_CLOTE ;
DR   A3DK03, AROA_CLOTH ;  Q482G5, AROA_COLP3 ;  Q8FRI2, AROA_COREF ;
DR   A4QC99, AROA_CORGB ;  Q9Z470, AROA_CORGL ;  B6J892, AROA_COXB1 ;
DR   B6J1D9, AROA_COXB2 ;  A9KCT5, AROA_COXBN ;  A9NC18, AROA_COXBR ;
DR   Q83E11, AROA_COXBU ;  Q0KDH9, AROA_CUPNH ;  Q46Y50, AROA_CUPPJ ;
DR   B3R368, AROA_CUPTR ;  B1WZH9, AROA_CYAA5 ;  B7KLE7, AROA_CYAP7 ;
DR   Q3Z992, AROA_DEHE1 ;  A5FRZ3, AROA_DEHSB ;  Q3ZZI5, AROA_DEHSC ;
DR   Q1IZN3, AROA_DEIGD ;  Q9RVD3, AROA_DEIRA ;  B1I3Z0, AROA_DESAP ;
DR   B8G2R0, AROA_DESHD ;  Q24V91, AROA_DESHY ;  A4J3N2, AROA_DESRM ;
DR   Q46550, AROA_DICNO ;  A5EWS0, AROA_DICNV ;  A8LSF0, AROA_DINSH ;
DR   A7ZJZ7, AROA_ECO24 ;  B7UMZ4, AROA_ECO27 ;  B7MHL7, AROA_ECO45 ;
DR   B7LDA0, AROA_ECO55 ;  P0A6D4, AROA_ECO57 ;  B5YT42, AROA_ECO5E ;
DR   B7NM67, AROA_ECO7I ;  B7MS23, AROA_ECO81 ;  B7M836, AROA_ECO8A ;
DR   C4ZQ34, AROA_ECOBW ;  B1X848, AROA_ECODH ;  A7ZYL1, AROA_ECOHS ;
DR   A1A9I5, AROA_ECOK1 ;  Q0TJE5, AROA_ECOL5 ;  Q8FJB6, AROA_ECOL6 ;
DR   B1IW23, AROA_ECOLC ;  P0A6D3, AROA_ECOLI ;  B7NAQ7, AROA_ECOLU ;
DR   B6I8Y0, AROA_ECOSE ;  B1LJV6, AROA_ECOSM ;  Q1RDV0, AROA_ECOUT ;
DR   Q9X4H2, AROA_EDWI9 ;  A4W8S8, AROA_ENT38 ;  P0DH70, AROA_ENTFA ;
DR   F2MTI3, AROA_ENTFO ;  A7MES7, AROA_ENTS8 ;  Q6D401, AROA_ERWCT ;
DR   B2VC79, AROA_ERWT9 ;  B5E9T1, AROA_GEOBB ;  Q5KXV5, AROA_GEOKA ;
DR   Q39XB8, AROA_GEOMG ;  B9LZG2, AROA_GEOSF ;  Q749Y6, AROA_GEOSL ;
DR   C6E2B1, AROA_GEOSM ;  A4IQ78, AROA_GEOTN ;  A5GE08, AROA_GEOUR ;
DR   Q7NLT3, AROA_GLOVI ;  Q5FTC0, AROA_GLUOX ;  Q0BQH9, AROA_GRABC ;
DR   Q7VLN9, AROA_HAEDU ;  Q4QL19, AROA_HAEI8 ;  A5UCH8, AROA_HAEIE ;
DR   A5UJ35, AROA_HAEIG ;  Q03421, AROA_HAEIN ;  Q0I320, AROA_HAES1 ;
DR   B0UT47, AROA_HAES2 ;  P52310, AROA_HAESO ;  A1WUI9, AROA_HALHL ;
DR   B9LUD2, AROA_HALLT ;  B0R558, AROA_HALS3 ;  Q9HQC1, AROA_HALSA ;
DR   Q18F09, AROA_HALWD ;  C4K4D4, AROA_HAMD5 ;  Q17YI6, AROA_HELAH ;
DR   Q7VJV4, AROA_HELHP ;  B6JMP3, AROA_HELP2 ;  B5Z850, AROA_HELPG ;
DR   Q1CSL4, AROA_HELPH ;  Q9ZKF7, AROA_HELPJ ;  B2UUF9, AROA_HELPS ;
DR   P56197, AROA_HELPY ;  A9AZ72, AROA_HERA2 ;  A4G861, AROA_HERAR ;
DR   Q0C5R4, AROA_HYPNA ;  Q5QZ50, AROA_IDILO ;  A6T1G3, AROA_JANMA ;
DR   Q28UI7, AROA_JANSC ;  B5XY87, AROA_KLEP3 ;  A6T701, AROA_KLEP7 ;
DR   P24497, AROA_KLEPN ;  B2GLU6, AROA_KOCRD ;  B1L5R5, AROA_KORCO ;
DR   B2GCR0, AROA_LACF3 ;  Q9CEU0, AROA_LACLA ;  P43905, AROA_LACLM ;
DR   Q02XD1, AROA_LACLS ;  Q88VL2, AROA_LACPL ;  C1D543, AROA_LARHH ;
DR   Q5X5E6, AROA_LEGPA ;  A5IBR1, AROA_LEGPC ;  Q5ZVM1, AROA_LEGPH ;
DR   Q5WWS9, AROA_LEGPL ;  B0SDL8, AROA_LEPBA ;  Q04U42, AROA_LEPBJ ;
DR   Q04ZI3, AROA_LEPBL ;  B0SM47, AROA_LEPBP ;  Q72PM1, AROA_LEPIC ;
DR   Q8F6P5, AROA_LEPIN ;  B1MYD1, AROA_LEUCK ;  Q03X10, AROA_LEUMM ;
DR   Q92A85, AROA_LISIN ;  C1KWM3, AROA_LISMC ;  Q71Y92, AROA_LISMF ;
DR   B8DC03, AROA_LISMH ;  Q8Y5Y0, AROA_LISMO ;  A0AK35, AROA_LISW6 ;
DR   Q2VZA8, AROA_MAGSA ;  A0L408, AROA_MAGSM ;  Q65S78, AROA_MANSM ;
DR   Q0ATJ1, AROA_MARMM ;  A6VXX9, AROA_MARMS ;  Q11C97, AROA_MESSB ;
DR   A6UTB9, AROA_META3 ;  Q8THH3, AROA_METAC ;  A7I8L8, AROA_METB6 ;
DR   Q12X18, AROA_METBU ;  B7KZL6, AROA_METC4 ;  Q608S5, AROA_METCA ;
DR   Q2FQ54, AROA_METHJ ;  Q57925, AROA_METJA ;  Q8TXN4, AROA_METKA ;
DR   A2SU05, AROA_METLZ ;  A4FWX2, AROA_METM5 ;  A9AAA7, AROA_METM6 ;
DR   A6VGE5, AROA_METM7 ;  Q8PXI0, AROA_METMA ;  A3CV28, AROA_METMJ ;
DR   Q6LXY8, AROA_METMP ;  B1ZLG6, AROA_METPB ;  B8GF70, AROA_METPE ;
DR   B1M0N9, AROA_METRJ ;  A5UJV0, AROA_METS3 ;  B0UC54, AROA_METS4 ;
DR   Q2NH05, AROA_METST ;  O26860, AROA_METTH ;  A0B7Z0, AROA_METTP ;
DR   A6UPK5, AROA_METVS ;  Q7TWY4, AROA_MYCBO ;  C1AH01, AROA_MYCBT ;
DR   A4TFB8, AROA_MYCGI ;  Q9CCI3, AROA_MYCLE ;  B2HES1, AROA_MYCMM ;
DR   Q73UN2, AROA_MYCPA ;  A3PWC1, AROA_MYCSJ ;  A1UCN4, AROA_MYCSK ;
DR   Q1BCB0, AROA_MYCSS ;  A5U7Q1, AROA_MYCTA ;  P22487, AROA_MYCTU ;
DR   A0PRD3, AROA_MYCUA ;  A1T5Z3, AROA_MYCVP ;  Q3IQG6, AROA_NATPD ;
DR   Q5F889, AROA_NEIG1 ;  B4RL93, AROA_NEIG2 ;  Q9JTT3, AROA_NEIMA ;
DR   Q9JYU1, AROA_NEIMB ;  A1KUN6, AROA_NEIMF ;  Q0AIZ5, AROA_NITEC ;
DR   Q82TD4, AROA_NITEU ;  Q1QRT1, AROA_NITHX ;  A9A231, AROA_NITMS ;
DR   Q3JEN6, AROA_NITOC ;  A6Q2R6, AROA_NITSB ;  Q3SW64, AROA_NITWN ;
DR   B2IYE4, AROA_NOSP7 ;  Q8YMB5, AROA_NOSS1 ;  Q2G8Q3, AROA_NOVAD ;
DR   Q8EQC1, AROA_OCEIH ;  A6WUV8, AROA_OCHA4 ;  Q04HC7, AROA_OENOB ;
DR   B6JCN2, AROA_OLICO ;  B1ZMW8, AROA_OPITP ;  A1B474, AROA_PARDP ;
DR   A7HPE1, AROA_PARL1 ;  P54220, AROA_PASHA ;  Q04570, AROA_PASMU ;
DR   Q8VP65, AROA_PASPI ;  C6DF65, AROA_PECCP ;  Q3A3D1, AROA_PELCD ;
DR   Q3B659, AROA_PELLD ;  B4SFD3, AROA_PELPB ;  A1ANP7, AROA_PELPD ;
DR   A5D1R9, AROA_PELTS ;  C0QS40, AROA_PERMH ;  P11043, AROA_PETHY ;
DR   A9BHP7, AROA_PETMO ;  B4RCK3, AROA_PHEZH ;  Q7N6D5, AROA_PHOLL ;
DR   Q6LPE1, AROA_PHOPR ;  Q6L1G5, AROA_PICTO ;  B4S4Q8, AROA_PROA2 ;
DR   A3PBY7, AROA_PROM0 ;  A8G3X9, AROA_PROM2 ;  A2CAX1, AROA_PROM3 ;
DR   A2BVS6, AROA_PROM5 ;  Q31BS1, AROA_PROM9 ;  B4ET25, AROA_PROMH ;
DR   Q7V8F4, AROA_PROMM ;  Q7V272, AROA_PROMP ;  A2BQ94, AROA_PROMS ;
DR   Q46LT7, AROA_PROMT ;  A4SD12, AROA_PROVI ;  Q48N21, AROA_PSE14 ;
DR   Q15T04, AROA_PSEA6 ;  Q3ILA2, AROA_PSEHT ;  P0A2Y4, AROA_PSES2 ;
DR   Q888I3, AROA_PSESM ;  Q4ZY26, AROA_PSEU2 ;  A1STZ0, AROA_PSYIN ;
DR   Q9V1H1, AROA_PYRAB ;  Q8U0A0, AROA_PYRFU ;  Q5JFT3, AROA_PYRKO ;
DR   B2U886, AROA_RALPJ ;  Q8Y0Y6, AROA_RALSO ;  B3PRH7, AROA_RHIE6 ;
DR   Q2KBU1, AROA_RHIEC ;  Q1MN56, AROA_RHIL3 ;  Q98CC1, AROA_RHILO ;
DR   B5ZS37, AROA_RHILW ;  Q92SV5, AROA_RHIME ;  C3MC80, AROA_RHISN ;
DR   C0ZX05, AROA_RHOE4 ;  C1B1F1, AROA_RHOOB ;  Q2J2F6, AROA_RHOP2 ;
DR   Q07UI1, AROA_RHOP5 ;  Q6NDP4, AROA_RHOPA ;  Q13ER0, AROA_RHOPS ;
DR   B3Q5Z7, AROA_RHOPT ;  Q2RXP5, AROA_RHORT ;  A3PPV7, AROA_RHOS1 ;
DR   Q3IW89, AROA_RHOS4 ;  Q0S2X1, AROA_RHOSR ;  A7NJA5, AROA_ROSCS ;
DR   Q161H2, AROA_ROSDO ;  A5UZF9, AROA_ROSS1 ;  A1AWR5, AROA_RUTMC ;
DR   A4FNI0, AROA_SACEN ;  B5F161, AROA_SALA4 ;  A9MHX5, AROA_SALAR ;
DR   Q57R23, AROA_SALCH ;  B5FQ51, AROA_SALDC ;  B5QYQ8, AROA_SALEP ;
DR   B5R8J5, AROA_SALG2 ;  P22299, AROA_SALGL ;  B4TD38, AROA_SALHS ;
DR   B4T142, AROA_SALNS ;  Q5PGG5, AROA_SALPA ;  A9N7V6, AROA_SALPB ;
DR   C0PXU4, AROA_SALPC ;  B5BBP9, AROA_SALPK ;  Q2S4R9, AROA_SALRD ;
DR   B4TRT9, AROA_SALSV ;  P19786, AROA_SALTI ;  P07637, AROA_SALTY ;
DR   A8GCH1, AROA_SERP5 ;  A1S6D3, AROA_SHEAM ;  B8EA95, AROA_SHEB2 ;
DR   A3D4A6, AROA_SHEB5 ;  A6WNN0, AROA_SHEB8 ;  A9L2X7, AROA_SHEB9 ;
DR   Q12NE1, AROA_SHEDO ;  Q081U4, AROA_SHEFN ;  B0TT43, AROA_SHEHH ;
DR   A3QEC0, AROA_SHELP ;  Q8EEH8, AROA_SHEON ;  A8H4A4, AROA_SHEPA ;
DR   A4Y732, AROA_SHEPC ;  B8CMH2, AROA_SHEPW ;  A0KWN7, AROA_SHESA ;
DR   A8FVN6, AROA_SHESH ;  Q0HIX1, AROA_SHESM ;  Q0HV11, AROA_SHESR ;
DR   A1RJF8, AROA_SHESW ;  B1KF47, AROA_SHEWM ;  B2TUH3, AROA_SHIB3 ;
DR   Q31YU3, AROA_SHIBS ;  Q32E25, AROA_SHIDS ;  O87006, AROA_SHIDY ;
DR   Q0SX08, AROA_SHIF8 ;  Q83RY8, AROA_SHIFL ;  Q9ZFF7, AROA_SHISO ;
DR   Q3Z3L4, AROA_SHISS ;  Q1GK84, AROA_SILST ;  Q2NUA9, AROA_SODGM ;
DR   P10748, AROA_SOLLC ;  Q01Q26, AROA_SOLUE ;  Q1GT16, AROA_SPHAL ;
DR   A7X2G5, AROA_STAA1 ;  A6U1T3, AROA_STAA2 ;  Q2FGX6, AROA_STAA3 ;
DR   Q05615, AROA_STAA8 ;  A5ISZ4, AROA_STAA9 ;  Q2YY90, AROA_STAAB ;
DR   Q5HFV9, AROA_STAAC ;  A6QH15, AROA_STAAE ;  P63584, AROA_STAAM ;
DR   P63585, AROA_STAAN ;  Q6GGU5, AROA_STAAR ;  Q6G998, AROA_STAAS ;
DR   A8Z444, AROA_STAAT ;  Q8NWN5, AROA_STAAW ;  B9DNV0, AROA_STACT ;
DR   Q5HP79, AROA_STAEQ ;  Q8CSI1, AROA_STAES ;  Q4L6G8, AROA_STAHJ ;
DR   Q49XS0, AROA_STAS1 ;  Q3K2B0, AROA_STRA1 ;  Q8E6F8, AROA_STRA3 ;
DR   Q8E0U0, AROA_STRA5 ;  Q82IU1, AROA_STRAW ;  C0MA42, AROA_STRE4 ;
DR   B4U246, AROA_STREM ;  A8AXY9, AROA_STRGC ;  Q8DUV8, AROA_STRMU ;
DR   Q99Z83, AROA_STRP1 ;  Q04JX6, AROA_STRP2 ;  P0CZ72, AROA_STRP3 ;
DR   B5E5M9, AROA_STRP4 ;  Q5XBK5, AROA_STRP6 ;  C1C7X2, AROA_STRP7 ;
DR   Q8P0H1, AROA_STRP8 ;  Q1JB43, AROA_STRPB ;  Q1JL87, AROA_STRPC ;
DR   Q1JGC1, AROA_STRPD ;  Q1J633, AROA_STRPF ;  A2RE13, AROA_STRPG ;
DR   B1ICH2, AROA_STRPI ;  B8ZKM0, AROA_STRPJ ;  Q48SV4, AROA_STRPM ;
DR   Q9S400, AROA_STRPN ;  P0CZ73, AROA_STRPQ ;  B5XM07, AROA_STRPZ ;
DR   Q8CWQ7, AROA_STRR6 ;  A4W069, AROA_STRS2 ;  C0MCK4, AROA_STRS7 ;
DR   A3CNV3, AROA_STRSV ;  Q5M0L5, AROA_STRT1 ;  Q5M551, AROA_STRT2 ;
DR   Q03LG9, AROA_STRTD ;  B9DSK8, AROA_STRU0 ;  C1CEW0, AROA_STRZJ ;
DR   C1CL80, AROA_STRZP ;  C1CQY4, AROA_STRZT ;  Q30S82, AROA_SULDN ;
DR   C3MZF0, AROA_SULIA ;  C4KIN0, AROA_SULIK ;  C3MRB5, AROA_SULIL ;
DR   C3MXK4, AROA_SULIM ;  C3NG04, AROA_SULIN ;  C3N7H2, AROA_SULIY ;
DR   A6Q7Q0, AROA_SULNB ;  Q980I5, AROA_SULSO ;  B2V630, AROA_SULSY ;
DR   Q96Y91, AROA_SULTO ;  Q31RQ5, AROA_SYNE7 ;  A0LLU6, AROA_SYNFM ;
DR   Q2JSF1, AROA_SYNJA ;  Q2JLV2, AROA_SYNJB ;  Q5N2J9, AROA_SYNP6 ;
DR   A5GKJ3, AROA_SYNPW ;  Q7U7H8, AROA_SYNPX ;  A5GT44, AROA_SYNR3 ;
DR   Q0I9Y0, AROA_SYNS3 ;  Q3AXB7, AROA_SYNS9 ;  Q3AKJ6, AROA_SYNSC ;
DR   Q0AX99, AROA_SYNWW ;  Q59975, AROA_SYNY3 ;  Q9HLE6, AROA_THEAC ;
DR   Q8DLY3, AROA_THEEB ;  Q9WYI0, AROA_THEMA ;  B9KBV6, AROA_THENN ;
DR   A5IK73, AROA_THEP1 ;  B0K928, AROA_THEP3 ;  B0K0J1, AROA_THEPX ;
DR   B1L9E5, AROA_THESQ ;  Q72LH1, AROA_THET2 ;  Q5SL36, AROA_THET8 ;
DR   Q8RB11, AROA_THETN ;  Q978S3, AROA_THEVO ;  B5YH68, AROA_THEYD ;
DR   Q31GD2, AROA_THICR ;  Q3SK83, AROA_THIDA ;  C4LEG3, AROA_TOLAT ;
DR   Q83I86, AROA_TROW8 ;  Q0W6Q9, AROA_UNCMA ;  B1GYQ3, AROA_UNCTG ;
DR   A5CWH5, AROA_VESOH ;  A5F7G5, AROA_VIBC3 ;  Q9KRB0, AROA_VIBCH ;
DR   C3LN54, AROA_VIBCM ;  Q5E3Z0, AROA_VIBF1 ;  B5FG60, AROA_VIBFM ;
DR   A7N1K3, AROA_VIBHB ;  Q87QX9, AROA_VIBPA ;  B7VM38, AROA_VIBSL ;
DR   Q7MJ45, AROA_VIBVY ;  Q7M8Y7, AROA_WOLSU ;  Q8PLY5, AROA_XANAC ;
DR   Q3BUZ1, AROA_XANC5 ;  Q4UTD1, AROA_XANC8 ;  B0RUW1, AROA_XANCB ;
DR   Q8PA95, AROA_XANCP ;  Q2P356, AROA_XANOM ;  B2SJJ3, AROA_XANOP ;
DR   Q5H081, AROA_XANOR ;  Q8RLV9, AROA_XENNA ;  Q9PB21, AROA_XYLFA ;
DR   Q87BU2, AROA_XYLFT ;  P19688, AROA_YERE8 ;  A7FJW9, AROA_YERP3 ;
DR   Q1CA73, AROA_YERPA ;  B2KA23, AROA_YERPB ;  Q60112, AROA_YERPE ;
DR   A9R7I2, AROA_YERPG ;  Q1CGG5, AROA_YERPN ;  A4TN18, AROA_YERPP ;
DR   Q66CI8, AROA_YERPS ;  B1JRD9, AROA_YERPY ;  Q93ED4, AROA_YERRU ;
DR   Q5NLJ0, AROA_ZYMMO ;
//
ID   2.5.1.20
DE   Rubber cis-polyprenylcistransferase.
AN   Rubber allyltransferase.
AN   Rubber transferase.
CA   Poly-cis-polyprenyl diphosphate + isopentenyl diphosphate = diphosphate +
CA   a poly-cis-polyprenyl diphosphate longer by one C(5) unit.
CC   -!- Rubber particles act as acceptor.
//
ID   2.5.1.21
DE   Squalene synthase.
AN   Farnesyl-diphosphate farnesyltransferase.
AN   Farnesyltransferase.
AN   Presqualene synthase.
AN   Presqualene-diphosphate synthase.
AN   Squalene synthetase.
CA   (1) 2 farnesyl diphosphate = diphosphate + presqualene diphosphate.
CA   (2) Presqualene diphosphate + NAD(P)H = squalene + diphosphate +
CA   NAD(P)(+).
CF   Manganese or magnesium.
CC   -!- This microsomal enzyme catalyzes the first committed step in the
CC       biosynthesis of sterols.
CC   -!- In the absence of NAD(P)H, presqualene diphosphate (PSPP) is
CC       accumulated.
CC   -!- When NAD(P)H is present, presqualene diphosphate does not dissociate
CC       from the enzyme during the synthesis of squalene from farnesyl
CC       diphosphate (FPP).
CC   -!- High concentrations of FPP inhibit the production of squalene but not
CC       of PSPP.
PR   PROSITE; PDOC00802;
DR   P53799, FDFT_ARATH ;  Q752X9, FDFT_ASHGO ;  Q32KR6, FDFT_BOVIN ;
DR   P78589, FDFT_CANAL ;  Q9HGZ6, FDFT_CANGA ;  O74165, FDFT_CYBJA ;
DR   Q54DR1, FDFT_DICDI ;  P37268, FDFT_HUMAN ;  P53798, FDFT_MOUSE ;
DR   Q7S4Z6, FDFT_NEUCR ;  P53800, FDFT_NICBE ;  Q5R6U3, FDFT_PONAB ;
DR   Q02769, FDFT_RAT   ;  P36596, FDFT_SCHPO ;  Q92459, FDFT_USTMA ;
DR   Q9Y753, FDFT_YARLI ;  P29704, FDFT_YEAST ;
//
ID   2.5.1.22
DE   Spermine synthase.
AN   Spermidine aminopropyltransferase.
CA   S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine +
CA   spermine.
CC   -!- Not identical with EC 2.5.1.16 or EC 2.5.1.23.
PR   PROSITE; PDOC01033;
DR   Q94BN2, SPSY_ARATH ;  Q3SZA5, SPSY_BOVIN ;  P52788, SPSY_HUMAN ;
DR   P97355, SPSY_MOUSE ;  Q12455, SPSY_YEAST ;
//
ID   2.5.1.23
DE   Sym-norspermidine synthase.
CA   S-adenosylmethioninamine + propane-1,3-diamine = 5'-methylthioadenosine +
CA   bis(3-aminopropyl)amine.
CC   -!- Not identical with EC 2.5.1.16 or EC 2.5.1.22.
//
ID   2.5.1.24
DE   Discadenine synthase.
AN   Discadenine synthetase.
CA   S-adenosyl-L-methionine + N(6)-(Delta(2)-isopentenyl)-adenine = S-methyl-
CA   5'-thioadenosine + discadenine.
//
ID   2.5.1.25
DE   tRNA-uridine aminocarboxypropyltransferase.
CA   S-adenosyl-L-methionine + tRNA uridine = S-methyl-5'-thioadenosine + tRNA
CA   3-(3-amino-3-carboxypropyl)-uridine.
//
ID   2.5.1.26
DE   Alkylglycerone-phosphate synthase.
AN   Alkyl-DHAP synthase.
AN   Alkyldihydroxyacetonephosphate synthase.
CA   1-acyl-glycerone 3-phosphate + a long-chain alcohol = an alkyl-glycerone
CA   3-phosphate + a long-chain acid anion.
CC   -!- The ester-linked fatty acid of the substrate is cleaved and replaced
CC       by a long-chain alcohol in an ether linkage.
DR   O45218, ADAS_CAEEL ;  P97275, ADAS_CAVPO ;  O96759, ADAS_DICDI ;
DR   Q9V778, ADAS_DROME ;  O00116, ADAS_HUMAN ;  Q8C0I1, ADAS_MOUSE ;
DR   Q9EQR2, ADAS_RAT   ;  O97157, ADAS_TRYBB ;
//
ID   2.5.1.27
DE   Adenylate dimethylallyltransferase.
AN   Adenylate isopentenyltransferase.
AN   Cytokinin synthase.
AN   Isopentenyltransferase.
CA   Dimethylallyl diphosphate + AMP = diphosphate + N(6)-
CA   (dimethylallyl)adenosine 5'-phosphate.
DR   Q94ID3, IPT1_ARATH ;  Q5GHF7, IPT_HUMLU  ;
//
ID   2.5.1.28
DE   Dimethylallylcistransferase.
AN   Neryl-diphosphate synthase.
CA   Dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate +
CA   neryl diphosphate.
CC   -!- Will not use larger prenyl diphosphates as efficient donors.
DR   C1K5M2, NDPS_SOLLC ;
//
ID   2.5.1.29
DE   Geranylgeranyl diphosphate synthase.
AN   Farnesyltransferase.
AN   Farnesyltranstransferase.
AN   Geranylgeranyl pyrophosphate synthase.
AN   Geranylgeranyl pyrophosphate synthetase.
AN   Geranylgeranyl-diphosphate synthase.
AN   Geranylgeranyl-PP synthetase.
CA   (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = diphosphate +
CA   geranylgeranyl diphosphate.
CC   -!- Some forms of this enzyme will also use geranyl diphosphate and
CC       dimethylallyl diphosphate as donors; it will not use larger prenyl
CC       diphosphates as efficient donors.
PR   PROSITE; PDOC00407;
DR   P48368, CRTE_CYAPA ;  P22873, CRTE_ESCVU ;  P21684, CRTE_PANAN ;
DR   P17060, CRTE_RHOCB ;  P54976, CRTE_RHOS4 ;  P34802, GGPP1_ARATH;
DR   O04046, GGPP2_ARATH;  Q9LUD9, GGPP3_ARATH;  Q9SLG2, GGPP4_ARATH;
DR   O22043, GGPP6_ARATH;  Q9ZU77, GGPP7_ARATH;  Q9LRR0, GGPP8_ARATH;
DR   Q9LUE1, GGPP9_ARATH;  Q9LJY2, GGPPA_ARATH;  Q9LIA0, GGPPB_ARATH;
DR   Q9LHR4, GGPPC_ARATH;  Q758K0, GGPPS_ASHGO;  P56966, GGPPS_BOVIN;
DR   P80042, GGPPS_CAPAN;  Q42698, GGPPS_CATRO;  Q54BK1, GGPPS_DICDI;
DR   Q92236, GGPPS_GIBFU;  Q94ID7, GGPPS_HEVBR;  O95749, GGPPS_HUMAN;
DR   Q9WTN0, GGPPS_MOUSE;  P0A5H9, GGPPS_MYCBO;  P0A5H8, GGPPS_MYCTU;
DR   P24322, GGPPS_NEUCR;  Q6F596, GGPPS_RAT  ;  Q9P885, GGPPS_RHIRA;
DR   O59703, GGPPS_SCHPO;  Q43133, GGPPS_SINAL;  Q12051, GGPPS_YEAST;
DR   P39464, GGPS_SULAC ;  P95999, GGPS_SULSO ;  Q65164, TPRT_ASFB7 ;
DR   P0C9E2, TPRT_ASFK5 ;  Q8V9T7, TPRT_ASFM2 ;  P0C9E0, TPRT_ASFP4 ;
DR   P0C9E1, TPRT_ASFWA ;
//
ID   2.5.1.30
DE   Heptaprenyl diphosphate synthase.
AN   All-trans-heptaprenyl-diphosphate synthase.
AN   HepPP synthase.
AN   Heptaprenyl pyrophosphate synthetase.
AN   Trans-hexaprenyltranstransferase.
CA   (2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate = 4 diphosphate
CA   + all-trans-heptaprenyl diphosphate.
CC   -!- This enzyme catalyzes the condensation reactions resulting in the
CC       formation of all-trans-heptaprenyl diphosphate, the isoprenoid side
CC       chain of ubiquinone-7 and menaquinone-7.
CC   -!- The enzyme adds four isopentenyl diphosphate molecules sequentially
CC       to farnesyl diphosphate with trans stereochemistry.
DR   P31112, HEPS1_BACSU;  P55784, HEPS1_GEOSE;  P31114, HEPS2_BACSU;
DR   P55785, HEPS2_GEOSE;
//
ID   2.5.1.31
DE   Di-trans,poly-cis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-
DE   diphosphate specific).
AN   Bactoprenyl-diphosphate synthase.
AN   Di-trans,poly-cis-undecaprenyl-diphosphate synthase.
AN   Di-trans,poly-cis-undecaprenylcistransferase.
AN   Undecaprenyl pyrophosphate synthase.
AN   Undecaprenyl pyrophosphate synthetase.
AN   Undecaprenyl-diphosphate synthase.
AN   UPP synthetase.
CA   (2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate = 8 diphosphate
CA   + di-trans,octa-cis-undecaprenyl diphosphate.
CC   -!- Undecaprenyl pyrophosphate synthase catalyzes the consecutive
CC       condensation reactions of a farnesyl diphosphate with eight
CC       isopentenyl diphosphates, in which new cis-double bonds are formed,
CC       to generate undecaprenyl diphosphate that serves as a lipid carrier
CC       for peptidoglycan synthesis of bacterial cell wall.
PR   PROSITE; PDOC00817;
DR   Q9ACU1, CRUP_STRCO ;  Q89W41, UPPS1_BRAJA;  P60480, UPPS1_CORDI;
DR   Q8FQR4, UPPS1_COREF;  P38118, UPPS1_CORGL;  P58563, UPPS1_NOSS1;
DR   Q82IC1, UPPS1_STRAW;  Q9L2H4, UPPS1_STRCO;  Q83HR7, UPPS1_TROW8;
DR   Q83GJ0, UPPS1_TROWT;  Q89KP7, UPPS2_BRAJA;  P60481, UPPS2_CORDI;
DR   Q8FNG2, UPPS2_COREF;  Q8NNC1, UPPS2_CORGL;  Q8YRL4, UPPS2_NOSS1;
DR   Q82BS5, UPPS2_STRAW;  Q9XA06, UPPS2_STRCO;  Q83HN8, UPPS2_TROW8;
DR   Q83GG2, UPPS2_TROWT;  Q6FCH1, UPPS_ACIAD ;  Q9YC66, UPPS_AERPE ;
DR   Q8UFL9, UPPS_AGRT5 ;  Q9ZEJ7, UPPS_ANAVT ;  O67291, UPPS_AQUAE ;
DR   Q8GLK9, UPPS_AQUPY ;  O29049, UPPS_ARCFU ;  Q81WL2, UPPS_BACAN ;
DR   Q732P6, UPPS_BACC1 ;  Q819Y1, UPPS_BACCR ;  Q9KA67, UPPS_BACHD ;
DR   Q6HEZ2, UPPS_BACHK ;  Q5WFT2, UPPS_BACSK ;  O31751, UPPS_BACSU ;
DR   Q8A1E0, UPPS_BACTN ;  Q8G7Y3, UPPS_BIFLO ;  Q7VRE1, UPPS_BLOFL ;
DR   Q7WJ90, UPPS_BORBR ;  O51146, UPPS_BORBU ;  Q7WA56, UPPS_BORPA ;
DR   Q7VYC6, UPPS_BORPE ;  Q57CY1, UPPS_BRUAB ;  Q8YHH3, UPPS_BRUME ;
DR   Q8G0D9, UPPS_BRUSU ;  P57330, UPPS_BUCAI ;  Q8K9S6, UPPS_BUCAP ;
DR   Q89AP0, UPPS_BUCBP ;  Q9PP99, UPPS_CAMJE ;  Q5HUX2, UPPS_CAMJR ;
DR   Q9A707, UPPS_CAUCR ;  Q5L6U0, UPPS_CHLAB ;  Q824H0, UPPS_CHLCV ;
DR   Q9PJU2, UPPS_CHLMU ;  Q9Z7Y7, UPPS_CHLPN ;  Q8KFQ5, UPPS_CHLTE ;
DR   O84456, UPPS_CHLTR ;  Q7NVZ0, UPPS_CHRVO ;  Q97I62, UPPS_CLOAB ;
DR   Q8XJQ9, UPPS_CLOPE ;  Q895K8, UPPS_CLOTE ;  Q83BV5, UPPS_COXBU ;
DR   Q9RRP1, UPPS_DEIRA ;  P60474, UPPS_ECO57 ;  P60473, UPPS_ECOL6 ;
DR   P60472, UPPS_ECOLI ;  Q831K9, UPPS_ENTFA ;  Q6D8D8, UPPS_ERWCT ;
DR   Q5NHX6, UPPS_FRATT ;  Q8RE08, UPPS_FUSNN ;  Q5L0J8, UPPS_GEOKA ;
DR   P60482, UPPS_GEOSL ;  Q7NPE7, UPPS_GLOVI ;  Q7VM20, UPPS_HAEDU ;
DR   P44938, UPPS_HAEIN ;  Q5V1I1, UPPS_HALMA ;  Q9HP68, UPPS_HALSA ;
DR   Q7VH74, UPPS_HELHP ;  Q8GDY3, UPPS_HELMO ;  Q9ZK05, UPPS_HELPJ ;
DR   P55984, UPPS_HELPY ;  Q5FJM7, UPPS_LACAC ;  Q74IR9, UPPS_LACJO ;
DR   Q9CDT1, UPPS_LACLA ;  Q88VJ8, UPPS_LACPL ;  Q5X7N9, UPPS_LEGPA ;
DR   Q5ZY69, UPPS_LEGPH ;  Q5WZ40, UPPS_LEGPL ;  Q72U10, UPPS_LEPIC ;
DR   Q8F144, UPPS_LEPIN ;  Q92C39, UPPS_LISIN ;  Q720A7, UPPS_LISMF ;
DR   Q8Y7G6, UPPS_LISMO ;  Q8TJQ7, UPPS_METAC ;  Q58767, UPPS_METJA ;
DR   Q8TXA7, UPPS_METKA ;  Q8PZ76, UPPS_METMA ;  O26334, UPPS_METTH ;
DR   O82827, UPPS_MICLU ;  P38119, UPPS_MYCLE ;  Q93AU4, UPPS_MYCPF ;
DR   P60479, UPPS_MYCTU ;  Q5F5X2, UPPS_NEIG1 ;  Q9JX35, UPPS_NEIMA ;
DR   Q9K1G6, UPPS_NEIMB ;  Q82TZ9, UPPS_NITEU ;  Q8EQU9, UPPS_OCEIH ;
DR   Q9CJL4, UPPS_PASMU ;  Q7N8P2, UPPS_PHOLL ;  Q6LN28, UPPS_PHOPR ;
DR   Q6KZ89, UPPS_PICTO ;  Q7MXJ4, UPPS_PORGI ;  Q7VBI9, UPPS_PROMA ;
DR   Q7V6T7, UPPS_PROMM ;  Q7V102, UPPS_PROMP ;  Q9HXY2, UPPS_PSEAE ;
DR   Q88MH6, UPPS_PSEPK ;  Q886N9, UPPS_PSESM ;  Q9V157, UPPS_PYRAB ;
DR   Q8ZU54, UPPS_PYRAE ;  Q8U0I8, UPPS_PYRFU ;  O59258, UPPS_PYRHO ;
DR   Q5JGE1, UPPS_PYRKO ;  Q8XZI7, UPPS_RALSO ;  Q98MB9, UPPS_RHILO ;
DR   Q92Q51, UPPS_RHIME ;  Q7UF53, UPPS_RHOBA ;  Q1RII8, UPPS_RICBR ;
DR   Q92I30, UPPS_RICCN ;  Q4ULR6, UPPS_RICFE ;  Q9ZDA7, UPPS_RICPR ;
DR   Q7PBU9, UPPS_RICSI ;  Q68WV4, UPPS_RICTY ;  Q5PD68, UPPS_SALPA ;
DR   Q8Z9A5, UPPS_SALTI ;  Q8ZRP2, UPPS_SALTY ;  Q9Y7K8, UPPS_SCHPO ;
DR   Q8EGH1, UPPS_SHEON ;  P60475, UPPS_SHIFL ;  Q5HGH1, UPPS_STAAC ;
DR   P60476, UPPS_STAAM ;  P60477, UPPS_STAAN ;  Q6GHH5, UPPS_STAAR ;
DR   Q6G9V3, UPPS_STAAS ;  Q8NWZ5, UPPS_STAAW ;  Q5HPT1, UPPS_STAEQ ;
DR   Q8CPG7, UPPS_STAES ;  Q4L5W2, UPPS_STAHJ ;  Q49X45, UPPS_STAS1 ;
DR   Q8E359, UPPS_STRA3 ;  Q8DXD5, UPPS_STRA5 ;  P20182, UPPS_STRFR ;
DR   Q8DSJ7, UPPS_STRMU ;  Q99XY1, UPPS_STRP1 ;  P0DH32, UPPS_STRP3 ;
DR   Q5X9U4, UPPS_STRP6 ;  Q8NZB2, UPPS_STRP8 ;  Q97SR4, UPPS_STRPN ;
DR   P0DH33, UPPS_STRPQ ;  Q8DRB3, UPPS_STRR6 ;  Q5M1N6, UPPS_STRT1 ;
DR   Q5M677, UPPS_STRT2 ;  Q9HH76, UPPS_SULAC ;  Q980W4, UPPS_SULSO ;
DR   Q976K2, UPPS_SULTO ;  Q7U7P7, UPPS_SYNPX ;  Q55482, UPPS_SYNY3 ;
DR   Q9HKQ0, UPPS_THEAC ;  Q8DI29, UPPS_THEEB ;  Q9X1B8, UPPS_THEMA ;
DR   O87197, UPPS_THET2 ;  Q5SH15, UPPS_THET8 ;  Q8RA26, UPPS_THETN ;
DR   Q97B58, UPPS_THEVO ;  Q73K76, UPPS_TREDE ;  O83612, UPPS_TREPA ;
DR   Q9KPV6, UPPS_VIBCH ;  Q5E3E3, UPPS_VIBF1 ;  Q87ME1, UPPS_VIBPA ;
DR   Q8DBF7, UPPS_VIBVU ;  Q7MIG4, UPPS_VIBVY ;  Q8D2G7, UPPS_WIGBR ;
DR   Q7M7V7, UPPS_WOLSU ;  Q8PMK9, UPPS_XANAC ;  Q8PAV7, UPPS_XANCP ;
DR   Q5H1E5, UPPS_XANOR ;  Q9PEH8, UPPS_XYLFA ;  Q87EH7, UPPS_XYLFT ;
DR   Q12063, UPPS_YEAST ;  Q8ZH61, UPPS_YERPE ;  Q667J4, UPPS_YERPS ;
DR   Q9X5F1, UPPS_ZYMMO ;  P60478, UPSS_MYCBO ;
//
ID   2.5.1.32
DE   Phytoene synthase.
AN   Geranylgeranyl-diphosphate geranylgeranyltransferase.
AN   Phytoene synthetase.
AN   Prephytoene-diphosphate synthase.
AN   PSase.
CA   (1) 2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate.
CA   (2) Prephytoene diphosphate = phytoene + diphosphate.
CF   Manganese.
CC   -!- The enzyme appears to be stereospecific, normally producing 15-cis-
CC       phytoene.
CC   -!- However, in Erwinia herbicola, the product is the 15-trans isomer.
DR   P22872, CRTB_ESCVU ;  P65861, CRTB_MYCBO ;  P65860, CRTB_MYCTU ;
DR   P21683, CRTB_PANAN ;  P54975, CRTB_PARSN ;  P17056, CRTB_RHOCB ;
DR   P54905, CRTB_RHOS4 ;  P54977, CRTB_STRGR ;  P37269, CRTB_SYNE7 ;
DR   P37294, CRTB_SYNY3 ;  P37270, CRTB_THET2 ;  O07333, CRTY_SPIPL ;
DR   Q9ACU1, CRUP_STRCO ;  E4UPP6, LCPS_ARTGP ;  A2QM49, LCPS_ASPNC ;
DR   Q2U4X9, LCPS_ASPOR ;  Q67GH9, LCPS_BLATR ;  E3Q717, LCPS_COLGM ;
DR   Q8X0Z1, LCPS_GIBFU ;  E4ZUB5, LCPS_LEPMJ ;  P37295, LCPS_NEUCR ;
DR   Q0V6M5, LCPS_PHANO ;  Q7Z859, LCPS_PHARH ;  Q9P854, LCPS_PHYBL ;
DR   B2ATB0, LCPS_PODAN ;  B2WAQ3, LCPS_PYRTR ;  Q9UUQ6, LCPS_RHIRA ;
DR   D1Z4K7, LCPS_SORMK ;  E6ZZ11, LCPS_SPORE ;  D4D802, LCPS_TRIVH ;
DR   Q4P0S6, LCPS_USTMA ;  P08196, PSY1_SOLLC ;  P37273, PSY2_SOLLC ;
DR   P37271, PSY_ARATH  ;  P37272, PSY_CAPAN  ;  P49293, PSY_CUCME  ;
DR   Q9SSU8, PSY_DAUCA  ;  P49085, PSY_MAIZE  ;  P53797, PSY_NARPS  ;
DR   P55350, Y4AC_RHISN ;
//
ID   2.5.1.33
DE   Transferred entry: 2.5.1.82 and 2.5.1.83.
//
ID   2.5.1.34
DE   4-dimethylallyltryptophan synthase.
AN   Tryptophan dimethylallyltransferase.
CA   Dimethylallyl diphosphate + L-tryptophan = diphosphate + 4-(3-methylbut-
CA   2-enyl)-L-tryptophan.
DR   Q6X2E2, DMAW1_ACRCO;  Q6X2E0, DMAW1_CLAPU;  Q6X2E1, DMAW2_ACRCO;
DR   Q9C141, DMAW2_CLAPU;  Q50EL0, DMAW_ASPFU ;  Q6X1E1, DMAW_BALOB ;
DR   Q12594, DMAW_CLAFS ;  Q6X2E3, DMAW_EPINE ;
//
ID   2.5.1.35
DE   Aspulvinone dimethylallyltransferase.
CA   2 dimethylallyl diphosphate + aspulvinone E = 2 diphosphate +
CA   aspulvinone H.
CC   -!- Will also use as acceptor aspulvinone G, a hydroxylated derivative of
CC       the complex phenolic pigment aspulvinone E.
//
ID   2.5.1.36
DE   Trihydroxypterocarpan dimethylallyltransferase.
AN   Dimethylallyl-diphosphate:(6aS,11aS)-3,6a,9-trihydroxypterocarpan
AN   dimethyltransferase.
AN   Dimethylallylpyrophosphate:3,6a,9-trihydroxypterocarpan
AN   dimethylallyltransferase.
AN   Dimethylallylpyrophosphate:trihydroxypterocarpan dimethylallyl
AN   transferase.
AN   Glyceollin synthase.
CA   (1) Dimethylallyl diphosphate + (6aS,11aS)-3,6a,9-trihydroxypterocarpan =
CA   diphosphate + 2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan.
CA   (2) Dimethylallyl diphosphate + (6aS,11aS)-3,6a,9-trihydroxypterocarpan =
CA   diphosphate + 4-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan.
CC   -!- Part of the glyceollin biosynthesis system in soybean.
//
ID   2.5.1.37
DE   Transferred entry: 4.4.1.20.
//
ID   2.5.1.38
DE   Isonocardicin synthase.
CA   S-adenosyl-L-methionine + nocardicin E = S-methyl-5'-thioadenosine +
CA   isonocardicin A.
CC   -!- Involved in the biosynthesis of the beta-lactam antibiotic nocardicin
CC       A.
//
ID   2.5.1.39
DE   4-hydroxybenzoate polyprenyltransferase.
AN   4-hydroxybenzoate nonaprenyltransferase.
CA   A polyprenyl diphosphate + 4-hydroxybenzoate = diphosphate + a 4-hydroxy-
CA   3-polyprenylbenzoate.
CC   -!- This enzyme, involved in the biosynthesis of ubiquinone, attaches a
CC       polyprenyl side chain to a 4-hydroxybenzoate ring, producing the
CC       first ubiquinone intermediate that is membrane bound.
CC   -!- The number of isoprenoid subunits in the side chain varies in
CC       different species.
CC   -!- The enzyme does not have any specificity concerning the length of the
CC       polyprenyl tail, and accepts tails of various lengths with similar
CC       efficiency.
PR   PROSITE; PDOC00727;
DR   Q93YP7, 4HPT_ARATH ;  Q16QL3, COQ2_AEDAE ;  Q2KIQ4, COQ2_BOVIN ;
DR   Q8I7J4, COQ2_CAEEL ;  Q54U71, COQ2_DICDI ;  Q9VHS7, COQ2_DROME ;
DR   Q298G6, COQ2_DROPS ;  Q96H96, COQ2_HUMAN ;  Q66JT7, COQ2_MOUSE ;
DR   Q499N4, COQ2_RAT   ;  Q10252, COQ2_SCHPO ;  P32378, COQ2_YEAST ;
//
ID   2.5.1.40
DE   Transferred entry: 4.2.3.9.
//
ID   2.5.1.41
DE   Phosphoglycerol geranylgeranyltransferase.
AN   (S)-3-O-geranylgeranylglyceryl phosphate synthase.
AN   GGGP synthase.
AN   GGGPS.
CA   Geranylgeranyl diphosphate + sn-glycerol 1-phosphate = diphosphate +
CA   sn-3-O-(geranylgeranyl)glycerol 1-phosphate.
CF   Magnesium.
CC   -!- Catalyzes the first pathway-specific step in the biosynthesis of the
CC       core membrane diether lipids in archaebacteria.
CC   -!- It catalyzes the alkylation of the primary hydroxy group in
CC       sn-glycerol 1-phosphate by geranylgeranyl diphosphate (GGPP) in a
CC       prenyltransfer reaction where a hydroxy group is the nucleophile in
CC       the acceptor substrate.
CC   -!- The other enzymes involved in the biosynthesis of polar lipids in
CC       archaea are EC 1.1.1.261, EC 2.5.1.42 and EC 2.7.7.67, which lead to
CC       the formation of CDP-unsaturated archaeol.
CC   -!- The final step in the pathway involves the addition of L-serine, with
CC       concomitant removal of CMP, leading to the production of unsaturated
CC       archaetidylserine.
DR   Q9YEF5, GGGPS_AERPE;  O29844, GGGPS_ARCFU;  A8MDA4, GGGPS_CALMQ;
DR   A0RYM1, GGGPS_CENSY;  Q5V1N9, GGGPS_HALMA;  B0R2Z3, GGGPS_HALS3;
DR   Q9HSF8, GGGPS_HALSA;  Q18KP6, GGGPS_HALWD;  A2BIS8, GGGPS_HYPBU;
DR   A8A9K6, GGGPS_IGNH4;  B1L6Q8, GGGPS_KORCO;  A6UW70, GGGPS_META3;
DR   Q8TJ20, GGGPS_METAC;  A7I6L7, GGGPS_METB6;  Q46EN8, GGGPS_METBF;
DR   Q12VH4, GGGPS_METBU;  Q2FQM4, GGGPS_METHJ;  Q58647, GGGPS_METJA;
DR   Q8TXM0, GGGPS_METKA;  A2SSK1, GGGPS_METLZ;  A4G0J0, GGGPS_METM5;
DR   A9A8T4, GGGPS_METM6;  A6VHZ5, GGGPS_METM7;  Q8PYC0, GGGPS_METMA;
DR   A3CTK2, GGGPS_METMJ;  Q6M1A9, GGGPS_METMP;  B8GHM9, GGGPS_METPE;
DR   A5UJF1, GGGPS_METS3;  A4YJ26, GGGPS_METS5;  Q2NET5, GGGPS_METST;
DR   O26652, GGGPS_METTH;  P0C882, GGGPS_METTM;  A0B8J3, GGGPS_METTP;
DR   A6URI9, GGGPS_METVS;  Q3IT31, GGGPS_NATPD;  A9A3Z1, GGGPS_NITMS;
DR   Q6L2N4, GGGPS_PICTO;  Q9UZN7, GGGPS_PYRAB;  Q8ZTX5, GGGPS_PYRAE;
DR   A4WLS7, GGGPS_PYRAR;  A3MUU3, GGGPS_PYRCJ;  Q8U213, GGGPS_PYRFU;
DR   O58851, GGGPS_PYRHO;  A1RRN9, GGGPS_PYRIL;  Q5JDY1, GGGPS_PYRKO;
DR   A3DN81, GGGPS_STAMF;  Q4JAS3, GGGPS_SULAC;  C3MZJ5, GGGPS_SULIA;
DR   C4KIS5, GGGPS_SULIK;  C3MRH0, GGGPS_SULIL;  C3MY66, GGGPS_SULIM;
DR   C3NFV6, GGGPS_SULIN;  C3N7L7, GGGPS_SULIY;  Q980N1, GGGPS_SULSO;
DR   Q975W8, GGGPS_SULTO;  Q9HJH3, GGGPS_THEAC;  C5A615, GGGPS_THEGJ;
DR   B1YAF0, GGGPS_THENV;  A1RXV6, GGGPS_THEPD;  C6A2A3, GGGPS_THESM;
DR   Q97AR4, GGGPS_THEVO;  Q0W6K5, GGGPS_UNCMA;
//
ID   2.5.1.42
DE   Geranylgeranylglycerol-phosphate geranylgeranyltransferase.
AN   (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase.
AN   DGGGP synthase.
AN   DGGGPS.
CA   Geranylgeranyl diphosphate + sn-3-O-(geranylgeranyl)glycerol 1-phosphate
CA   = diphosphate + 2,3-bis-O-(geranylgeranyl)glycerol 1-phosphate.
CF   Magnesium.
CC   -!- Carries out the second prenyltransfer reaction involved in the
CC       formation of polar membrane lipids in archaea.
CC   -!- 4-hydroxybenzoate, 1,4-dihydroxy 2-naphthoate, homogentisate and
CC       alpha-glycerophosphate cannot act as prenyl-acceptor substrates.
CC   -!- The other enzymes involved in the biosynthesis of polar lipids in
CC       archaea are EC 1.1.1.261, EC 2.5.1.41, which, together with this
CC       enzyme, alkylates the hydroxy groups of glycerol 1-phosphate to yield
CC       unsaturated archaetidic acid, which is acted upon by EC 2.7.7.67 to
CC       form CDP-unsaturated archaeol.
CC   -!- The final step in the pathway involves the addition of L-serine, with
CC       concomitant removal of CMP, leading to the production of unsaturated
CC       archaetidylserine.
DR   B0R3S1, DGGGP_HALS3;  Q9HRP0, DGGGP_HALSA;  Q18J00, DGGGP_HALWD;
DR   A2BIU7, DGGGP_HYPBU;  A8A9J7, DGGGP_IGNH4;  B1L6Z7, DGGGP_KORCO;
DR   A6UVU6, DGGGP_META3;  Q8TS44, DGGGP_METAC;  A7I9E7, DGGGP_METB6;
DR   Q46BD9, DGGGP_METBF;  Q12VF3, DGGGP_METBU;  Q2FN44, DGGGP_METHJ;
DR   Q57727, DGGGP_METJA;  Q8TWS9, DGGGP_METKA;  A2SRL0, DGGGP_METLZ;
DR   A4G0P3, DGGGP_METM5;  A9A8Y7, DGGGP_METM6;  A6VHU1, DGGGP_METM7;
DR   Q8PV96, DGGGP_METMA;  A3CW74, DGGGP_METMJ;  Q6LWN2, DGGGP_METMP;
DR   A5ULR8, DGGGP_METS3;  A4YI21, DGGGP_METS5;  Q2NGM1, DGGGP_METST;
DR   O27170, DGGGP_METTH;  A0B8A0, DGGGP_METTP;  A6UQV8, DGGGP_METVS;
DR   Q3INH7, DGGGP_NATPD;  Q9V2P5, DGGGP_PYRAB;  Q8TZM7, DGGGP_PYRFU;
DR   O57753, DGGGP_PYRHO;  Q5JDN5, DGGGP_PYRKO;  Q4J8K2, DGGGP_SULAC;
DR   Q9UWY6, DGGGP_SULSO;  Q971A3, DGGGP_SULTO;  C5A1J7, DGGGP_THEGJ;
DR   B6YW76, DGGGP_THEON;  A1S066, DGGGP_THEPD;  C6A2C9, DGGGP_THESM;
//
ID   2.5.1.43
DE   Nicotianamine synthase.
CA   3 S-adenosyl-L-methionine = 3 S-methyl-5'-thioadenosine + nicotianamine.
PR   PROSITE; PDOC51142;
DR   Q9FF79, NAS1_ARATH ;  Q9ZQV9, NAS1_HORVU ;  A2XFU4, NAS1_ORYSI ;
DR   Q0DSH9, NAS1_ORYSJ ;  Q9FKT9, NAS2_ARATH ;  Q9ZQV7, NAS2_HORVU ;
DR   A2XFU5, NAS2_ORYSI ;  Q10MI9, NAS2_ORYSJ ;  O80483, NAS3_ARATH ;
DR   Q9ZQV8, NAS3_HORVU ;  A2YQ58, NAS3_ORYSI ;  Q0D3F2, NAS3_ORYSJ ;
DR   Q9C7X5, NAS4_ARATH ;  Q9ZQV6, NAS4_HORVU ;  Q9ZQV3, NAS6_HORVU ;
DR   Q9ZWH8, NAS7_HORVU ;  Q9XFB6, NAS8_HORVU ;  Q9XFB7, NAS9_HORVU ;
DR   Q9XGI7, NAS_SOLLC  ;
//
ID   2.5.1.44
DE   Homospermidine synthase.
CA   (1) 2 putrescine = sym-homospermidine + NH(3) + H(+).
CA   (2) Putrescine + spermidine = sym-homospermidine + propane 1,3-diamine.
CF   NAD.
CC   -!- The reaction of this enzyme occurs in three steps, with some of the
CC       intermediates presumably remaining enzyme-bound: NAD(+)-dependent
CC       dehydrogenation of putrescine, transfer of the 4-aminobutylidene
CC       group from dehydroputrescine to a second molecule of putrescine and
CC       reduction of the imine intermediate to form homospermidine.
CC   -!- Hence the overall reaction is transfer of a 4-aminobutyl group.
CC   -!- Differs from EC 2.5.1.45, which cannot use putrescine as donor of the
CC       aminobutyl group.
DR   Q98H64, HSS_RHILO  ;  O32323, HSS_RHOVI  ;
//
ID   2.5.1.45
DE   Homospermidine synthase (spermidine-specific).
CA   Spermidine + putrescine = sym-homospermidine + propane-1,3-diamine.
CF   NAD.
CC   -!- The reaction of this enzyme occurs in three steps:
CC       (1) NAD(+)-dependent dehydrogenation of spermidine.
CC       (2) Transfer of the 4-aminobutylidene group from dehydrospermidine to
CC       a second molecule of putrescine.
CC       (3) Reduction of the imine intermediate to form homospermidine.
CC   -!- Hence the overall reaction is transfer of a 4-aminobutyl group.
CC   -!- This enzyme is more specific than EC 2.5.1.44 which is found in
CC       bacteria, as it cannot use putrescine as donor of the 4-aminobutyl
CC       group.
CC   -!- Forms part of the biosynthetic pathway of the poisonous pyrrolizidine
CC       alkaloids of the ragworts (Senecio).
DR   Q9SC13, HSS1_SENVE ;  Q9M4B0, HSS1_SENVU ;  P60038, HSS2_SENVE ;
//
ID   2.5.1.46
DE   Deoxyhypusine synthase.
AN   (4-aminobutyl)lysine synthase.
AN   [eIF-5A]-deoxyhypusine synthase.
AN   Spermidine dehydrogenase.
CA   [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine +
CA   propane-1,3-diamine.
CF   NAD.
CC   -!- The eukaryotic initiation factor eIF5A contains a hypusine residue
CC       that is essential for activity.
CC   -!- Catalyzes the first reaction of hypusine formation from one specific
CC       lysine residue of the eIF5A precursor.
CC   -!- The reaction occurs in four steps: NAD(+)-dependent dehydrogenation
CC       of spermidine (1a), formation of an enzyme-imine intermediate by
CC       transfer of the 4-aminobutylidene group from dehydrospermidine to the
CC       active site lysine residue (1b), transfer of the same
CC       4-aminobutylidene group from the enzyme intermediate to the e1F5A
CC       precursor (1c), reduction of the e1F5A-imine intermediate to form a
CC       deoxyhypusine residue (1d).
CC   -!- Hence the overall reaction is transfer of a 4-aminobutyl group.
CC   -!- For the plant enzyme, homospermidine can substitute for spermidine
CC       and putrescine can substitute for the lysine residue of the eIF5A
CC       precursor.
CC   -!- Hypusine is formed from deoxyhypusine by the action of EC 1.14.99.29.
CC   -!- Formerly EC 1.1.1.249.
DR   O28088, DHYS1_ARCFU;  Q8TS38, DHYS1_METAC;  Q8PV89, DHYS1_METMA;
DR   O27984, DHYS2_ARCFU;  Q8TLM3, DHYS2_METAC;  Q8Q051, DHYS2_METMA;
DR   Q9YE72, DHYS_AERPE ;  Q9FI94, DHYS_ARATH ;  Q75EW4, DHYS_ASHGO ;
DR   Q6EWQ6, DHYS_BOVIN ;  Q6RJS2, DHYS_BRANA ;  Q9XXJ0, DHYS_CAEEL ;
DR   Q6FRN2, DHYS_CANGA ;  Q6BJH5, DHYS_DEBHA ;  Q9AXQ8, DHYS_DIACA ;
DR   Q54MQ7, DHYS_DICDI ;  Q9VSF4, DHYS_DROME ;  Q8SQN2, DHYS_ENCCU ;
DR   B0R5L2, DHYS_HALS3 ;  Q9HPX2, DHYS_HALSA ;  P49366, DHYS_HUMAN ;
DR   A8AA61, DHYS_IGNH4 ;  Q6CNG7, DHYS_KLULA ;  Q58224, DHYS_METJA ;
DR   Q8TXD7, DHYS_METKA ;  A4YHK6, DHYS_METS5 ;  Q977X6, DHYS_METTE ;
DR   O26230, DHYS_METTH ;  A6URC0, DHYS_METVS ;  Q3TXU5, DHYS_MOUSE ;
DR   Q9AXQ9, DHYS_MUSAC ;  P49365, DHYS_NEUCR ;  Q6KZL5, DHYS_PICTO ;
DR   Q9V0N5, DHYS_PYRAB ;  Q8ZT09, DHYS_PYRAE ;  A3MVC9, DHYS_PYRCJ ;
DR   Q8U407, DHYS_PYRFU ;  O50105, DHYS_PYRHO ;  Q5JEY0, DHYS_PYRKO ;
DR   Q6AY53, DHYS_RAT   ;  O94337, DHYS_SCHPO ;  Q9SC14, DHYS_SENVE ;
DR   Q9AXR0, DHYS_SOLLC ;  Q4J978, DHYS_SULAC ;  C3N5B4, DHYS_SULIA ;
DR   C4KGY0, DHYS_SULIK ;  C3MPN8, DHYS_SULIL ;  C3MYN2, DHYS_SULIM ;
DR   C3NHT5, DHYS_SULIN ;  C3NDW8, DHYS_SULIY ;  Q97ZF1, DHYS_SULSO ;
DR   Q971T3, DHYS_SULTO ;  Q9HL74, DHYS_THEAC ;  C5A5L0, DHYS_THEGJ ;
DR   B6YVB1, DHYS_THEON ;  Q97BN6, DHYS_THEVO ;  Q9SC80, DHYS_TOBAC ;
DR   Q6CG56, DHYS_YARLI ;  P38791, DHYS_YEAST ;
//
ID   2.5.1.47
DE   Cysteine synthase.
AN   Acetylserine sulfhydrylase.
AN   Cysteine synthetase.
AN   O(3)-acetyl-L-serine acetate-lyase (adding hydrogen-sulfide).
AN   O-acetyl-L-serine sulfhydrylase.
AN   O-acetyl-L-serine sulfohydrolase.
AN   O-acetylserine (thiol)-lyase.
AN   O-acetylserine (thiol)-lyase A.
AN   O-acetylserine sulfhydrylase.
AN   OAS sulfhydrylase.
CA   O(3)-acetyl-L-serine + H(2)S = L-cysteine + acetate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Some alkyl thiols, cyanide, pyrazole and some other heterocyclic
CC       compounds can act as acceptors.
CC   -!- Not identical with EC 2.5.1.51, EC 2.5.1.52 and EC 2.5.1.53.
CC   -!- Formerly EC 4.2.99.8.
PR   PROSITE; PDOC00700;
DR   P47998, CYSK1_ARATH;  O23733, CYSK1_BRAJU;  Q9XEA6, CYSK1_ORYSJ;
DR   O59701, CYSK1_SCHPO;  O23735, CYSK2_BRAJU;  Q9XEA8, CYSK2_ORYSJ;
DR   P87131, CYSK2_SCHPO;  O22682, CYSK4_ARATH;  Q43725, CYSKM_ARATH;
DR   P47999, CYSKP_ARATH;  P31300, CYSKP_CAPAN;  O81155, CYSKP_SOLTU;
DR   P32260, CYSKP_SPIOL;  P37887, CYSK_BACSU ;  P57171, CYSK_BUCAI ;
DR   Q8KA48, CYSK_BUCAP ;  Q43317, CYSK_CITLA ;  P81340, CYSK_CLOPA ;
DR   Q54CN7, CYSK_DICDI ;  P0ABK6, CYSK_ECO57 ;  P0ABK5, CYSK_ECOLI ;
DR   P50867, CYSK_EMENI ;  Q59447, CYSK_FLAS3 ;  P45040, CYSK_HAEIN ;
DR   P80608, CYSK_MAIZE ;  P0A535, CYSK_MYCBO ;  O32978, CYSK_MYCLE ;
DR   P0A534, CYSK_MYCTU ;  Q7DDL5, CYSK_NEIMB ;  P84538, CYSK_POPEU ;
DR   P0A1E4, CYSK_SALTI ;  P0A1E3, CYSK_SALTY ;  O81154, CYSK_SOLTU ;
DR   Q00834, CYSK_SPIOL ;  Q5HIG2, CYSK_STAAC ;  P63870, CYSK_STAAM ;
DR   P63871, CYSK_STAAN ;  Q6GJF8, CYSK_STAAR ;  Q6GBX5, CYSK_STAAS ;
DR   P63872, CYSK_STAAW ;  Q5HRP1, CYSK_STAEQ ;  Q8CMT6, CYSK_STAES ;
DR   Q59918, CYSK_STAHA ;  Q5XAQ3, CYSK_STRP6 ;  P73410, CYSK_SYNY3 ;
DR   P38076, CYSK_WHEAT ;  P53206, CYSK_YEAST ;  O67507, CYSM_AQUAE ;
DR   O34476, CYSM_BACSU ;  P71128, CYSM_CAMJE ;  P16703, CYSM_ECOLI ;
DR   Q9ZMW6, CYSM_HELPJ ;  P56067, CYSM_HELPY ;  Q9I526, CYSM_PSEAE ;
DR   P48028, CYSM_PSESY ;  P29848, CYSM_SALTY ;  Q9YBL2, CYSO_AERPE ;
DR   Q92441, MET17_KLULA;  P06106, MET17_YEAST;  Q59966, SRPG_SYNE7 ;
DR   P55708, Y4XP_RHISN ;
//
ID   2.5.1.48
DE   Cystathionine gamma-synthase.
AN   Cystathionine synthase.
AN   Cystathionine synthetase.
AN   Homoserine O-transsuccinylase.
AN   Homoserine transsuccinylase.
AN   O-succinyl-L-homoserine succinate-lyase (adding cysteine).
AN   O-succinylhomoserine (thiol)-lyase.
AN   O-succinylhomoserine synthase.
AN   O-succinylhomoserine synthetase.
CA   O(4)-succinyl-L-homoserine + L-cysteine = L-cystathionine + succinate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Also reacts with H(2)S and methanethiol as replacing agents,
CC       producing homocysteine and methionine, respectively.
CC   -!- In the absence of thiol, can also catalyze beta,gamma-elimination to
CC       form 2-oxobutanoate, succinate and ammonia.
CC   -!- Formerly EC 4.2.99.9.
PR   PROSITE; PDOC00677;
DR   P38675, MET7_NEUCR ;  O74314, MET7_SCHPO ;  P47164, MET7_YEAST ;
DR   P55217, METB_ARATH ;  O31631, METB_BACSU ;  P00935, METB_ECOLI ;
DR   P44502, METB_HAEIN ;  Q9ZMW7, METB_HELPJ ;  P56069, METB_HELPY ;
DR   P24601, METB_HERAU ;  P66876, METB_MYCBO ;  P46807, METB_MYCLE ;
DR   P66875, METB_MYCTU ;  Q12198, METW_YEAST ;  Q04533, METX_YEAST ;
//
ID   2.5.1.49
DE   O-acetylhomoserine aminocarboxypropyltransferase.
AN   Methionine synthase.
AN   O-acetyl-L-homoserine acetate-lyase (adding methanethiol).
AN   O-acetyl-L-homoserine sulfhydrolase.
AN   O-acetylhomoserine (thiol)-lyase.
AN   O-acetylhomoserine sulfhydrolase.
AN   OAH sulfhydrylase.
CA   O-acetyl-L-homoserine + methanethiol = L-methionine + acetate.
CC   -!- Also reacts with other thiols and H(2)S, producing homocysteine or
CC       thioethers.
CC   -!- The name methionine synthase is more commonly applied to EC 2.1.1.13.
CC   -!- The enzyme from Saccharomyces cerevisiae also catalyzes the reaction
CC       of EC 2.5.1.47, but more slowly.
CC   -!- Formerly EC 4.2.99.10.
PR   PROSITE; PDOC00677;
DR   P50125, CYSD_EMENI ;  O13326, CYSD_SCHPO ;  Q92441, MET17_KLULA;
DR   P06106, MET17_YEAST;  O31631, METB_BACSU ;
//
ID   2.5.1.50
DE   Zeatin 9-aminocarboxyethyltransferase.
AN   Beta-(9-cytokinin)-alanine synthase.
AN   Beta-(9-cytokinin)alanine synthase.
AN   Lupinate synthetase.
AN   Lupinic acid synthase.
AN   Lupinic acid synthetase.
AN   O-acetyl-L-serine acetate-lyase (adding N(6)-substituted adenine).
CA   O-acetyl-L-serine + zeatin = lupinate + acetate.
CC   -!- The enzyme acts not only on zeatin but also on other N(6)-substituted
CC       adenines.
CC   -!- The reaction destroys their cytokinin activity and forms the
CC       corresponding 3-(adenin-9-yl)-L-alanine.
CC   -!- Formerly EC 4.2.99.13.
//
ID   2.5.1.51
DE   Beta-pyrazolylalanine synthase.
AN   Beta-(1-pyrazolyl)alanine synthase.
AN   Beta-pyrazolealanine synthase.
AN   Beta-pyrazolylalanine synthase (acetylserine).
AN   BPA-synthase.
AN   O(3)-acetyl-L-serine acetate-lyase (adding pyrazole).
AN   Pyrazolealanine synthase.
AN   Pyrazolylalaninase.
CA   O(3)-acetyl-L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + acetate.
CC   -!- Highly specific for acetylserine and pyrazole.
CC   -!- Not identical with EC 2.5.1.52.
CC   -!- Formerly EC 4.2.99.14 and EC 4.2.99.17.
DR   Q43317, CYSK_CITLA ;
//
ID   2.5.1.52
DE   L-mimosine synthase.
AN   O(3)-acetyl-L-serine acetate-lyase (adding 3,4-dihydroxypyridin-1-yl).
CA   O(3)-acetyl-L-serine + 3,4-dihydroxypyridine = 3-(3,4-dihydroxypyridin-1-
CA   yl)-L-alanine + acetate.
CC   -!- Brings about the biosynthesis of L-mimosine in Leucaena sp. and
CC       Mimosa.
CC   -!- Not identical with EC 2.5.1.51.
CC   -!- Formerly EC 4.2.99.15.
DR   Q43317, CYSK_CITLA ;
//
ID   2.5.1.53
DE   Uracilylalanine synthase.
AN   Isowillardiine synthase.
AN   O(3)-acetyl-L-serine acetate-lyase (adding uracil).
AN   Willardiine synthase.
CA   O(3)-acetyl-L-serine + uracil = 3-(uracil-1-yl)-L-alanine + acetate.
CC   -!- Both L-willardiine and L-isowillardiine are produced in the reaction.
CC   -!- Not identical with EC 2.5.1.47.
CC   -!- Formerly EC 4.2.99.16.
//
ID   2.5.1.54
DE   3-deoxy-7-phosphoheptulonate synthase.
AN   2-dehydro-3-deoxy-phosphoheptonate aldolase.
AN   2-keto-3-deoxy-D-arabino-heptonic acid 7-phosphate synthetase.
AN   3-deoxy-D-arabino-2-heptulosonic acid 7-phosphate synthetase.
AN   3-deoxy-D-arabino-heptolosonate-7-phosphate synthetase.
AN   3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase.
AN   7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate
AN   lyase (pyruvate-phosphorylating).
AN   7-phospho-2-keto-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate
AN   lyase (pyruvate-phosphorylating).
AN   D-erythrose-4-phosphate-lyase.
AN   D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating).
AN   DAH7-P synthase.
AN   DAHP synthase.
AN   Deoxy-D-arabino-heptulosonate-7-phosphate synthetase.
AN   DHAP synthase.
AN   DS-Co.
AN   DS-Mn.
AN   KDPH synthase.
AN   KDPH synthetase.
AN   Phospho-2-dehydro-3-deoxyheptonate aldolase.
AN   Phospho-2-keto-3-deoxyheptanoate aldolase.
AN   Phospho-2-keto-3-deoxyheptonate aldolase.
AN   Phospho-2-keto-3-deoxyheptonic aldolase.
AN   Phospho-2-oxo-3-deoxyheptonate aldolase.
CA   Phosphoenolpyruvate + D-erythrose 4-phosphate + H(2)O = 3-deoxy-D-
CA   arabino-hept-2-ulosonate 7-phosphate + phosphate.
CC   -!- Formerly EC 4.1.2.15.
DR   P29976, AROF_ARATH ;  P34725, AROF_CANAL ;  A0MH68, AROF_CATRO ;
DR   P00888, AROF_ECOLI ;  Q02285, AROF_ENTAG ;  P80576, AROF_NEUCR ;
DR   Q75LR2, AROF_ORYSJ ;  P0A1B6, AROF_SALTI ;  P0A1B5, AROF_SALTY ;
DR   Q09755, AROF_SCHPO ;  P37215, AROF_SOLLC ;  P21357, AROF_SOLTU ;
DR   P80574, AROF_STRCO ;  P55911, AROF_STRLI ;  P80575, AROF_STRRM ;
DR   Q9WYH8, AROF_THEMA ;  P27608, AROF_TOBAC ;  P14843, AROF_YEAST ;
DR   Q44093, AROG_AMYME ;  Q00218, AROG_ARATH ;  P39912, AROG_BACSU ;
DR   P79023, AROG_CANAL ;  P35170, AROG_CORGL ;  P0AB92, AROG_ECO57 ;
DR   P0AB91, AROG_ECOLI ;  P44303, AROG_HAEIN ;  Q75W16, AROG_ORYSJ ;
DR   Q9UT09, AROG_SCHPO ;  P37216, AROG_SOLLC ;  P37822, AROG_SOLTU ;
DR   P32449, AROG_YEAST ;  P57224, AROH_BUCAI ;  P46245, AROH_BUCAP ;
DR   Q89AW0, AROH_BUCBP ;  Q8X5W4, AROH_ECO57 ;  Q8FH32, AROH_ECOL6 ;
DR   P00887, AROH_ECOLI ;  O54459, AROH_ENTAG ;  Q8Z6I9, AROH_SALTI ;
DR   Q8ZPS4, AROH_SALTY ;  P59736, AROH_SHIFL ;  Q51517, PHZC_PSECL ;
DR   Q51789, PHZC_PSEFL ;
//
ID   2.5.1.55
DE   3-deoxy-8-phosphooctulonate synthase.
AN   2-dehydro-3-deoxy-D-octonate-8-phosphate D-arabinose-5-phosphate-lyase
AN   (pyruvate-phosphorylating).
AN   2-dehydro-3-deoxy-phosphooctonate aldolase.
AN   2-keto-3-deoxy-8-phosphooctonic synthetase.
AN   3-deoxy-D-manno-octulosonate-8-phosphate synthase.
AN   3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase.
AN   3-deoxy-D-mannooctulosonate-8-phosphate synthetase.
AN   3-deoxyoctulosonic 8-phosphate synthetase.
AN   KDO-8-P synthase.
AN   KDO-8-phosphate synthetase.
AN   KDOP synthase.
AN   Phospho-2-keto-3-deoxyoctonate aldolase.
CA   Phosphoenolpyruvate + D-arabinose 5-phosphate + H(2)O = 2-dehydro-3-
CA   deoxy-D-octonate 8-phosphate + phosphate.
CC   -!- Formerly EC 4.1.2.16.
DR   Q63SP9, KDSA1_BURPS;  Q88MG0, KDSA1_PSEPK;  Q63RA1, KDSA2_BURPS;
DR   Q88LX0, KDSA2_PSEPK;  B0BZZ8, KDSA_ACAM1 ;  A1TLS9, KDSA_ACIAC ;
DR   Q6FAT8, KDSA_ACIAD ;  B7H226, KDSA_ACIB3 ;  B2I2A6, KDSA_ACIBC ;
DR   Q1IKD0, KDSA_ACIBL ;  B0VQI5, KDSA_ACIBS ;  A3M5Y2, KDSA_ACIBT ;
DR   B0V676, KDSA_ACIBY ;  B9MEQ6, KDSA_ACIET ;  B7J6R3, KDSA_ACIF2 ;
DR   B5EPM6, KDSA_ACIF5 ;  A1W4R2, KDSA_ACISJ ;  B3GZI6, KDSA_ACTP7 ;
DR   B0BU69, KDSA_ACTPJ ;  O68662, KDSA_ACTPL ;  A6VP95, KDSA_ACTSZ ;
DR   Q8UFH3, KDSA_AGRT5 ;  Q0A7K3, KDSA_ALHEH ;  B6EHH9, KDSA_ALISL ;
DR   O66496, KDSA_AQUAE ;  Q9AV97, KDSA_ARATH ;  Q5NZ70, KDSA_AROAE ;
DR   A1K7F7, KDSA_AZOSB ;  C1DSS7, KDSA_AZOVD ;  A1US93, KDSA_BARBK ;
DR   Q6G409, KDSA_BARHE ;  Q6G026, KDSA_BARQU ;  A9IS46, KDSA_BART1 ;
DR   P61653, KDSA_BDEBA ;  Q2KVK9, KDSA_BORA1 ;  Q7WD73, KDSA_BORBR ;
DR   Q7W5N7, KDSA_BORPA ;  A9IIP6, KDSA_BORPD ;  Q7VW77, KDSA_BORPE ;
DR   Q89KV0, KDSA_BRAJA ;  A5EK16, KDSA_BRASB ;  A4YVC7, KDSA_BRASO ;
DR   B2S5Y4, KDSA_BRUA1 ;  Q2YPU9, KDSA_BRUA2 ;  Q57D06, KDSA_BRUAB ;
DR   A9M5E6, KDSA_BRUC2 ;  C0RJA4, KDSA_BRUMB ;  Q8YHF1, KDSA_BRUME ;
DR   A5VQQ8, KDSA_BRUO2 ;  B0CGT3, KDSA_BRUSI ;  Q8G0G2, KDSA_BRUSU ;
DR   Q1BHS1, KDSA_BURCA ;  B1JUY7, KDSA_BURCC ;  A0K8N2, KDSA_BURCH ;
DR   B4EDA2, KDSA_BURCJ ;  A9AGW1, KDSA_BURM1 ;  A3ML78, KDSA_BURM7 ;
DR   A2SAU6, KDSA_BURM9 ;  Q62J09, KDSA_BURMA ;  A1V5K3, KDSA_BURMS ;
DR   B2JIX1, KDSA_BURP8 ;  A4JFY6, KDSA_BURVG ;  Q13X06, KDSA_BURXL ;
DR   A8FKH1, KDSA_CAMJ8 ;  A7H4Z3, KDSA_CAMJD ;  Q9PIB8, KDSA_CAMJE ;
DR   A1VYA4, KDSA_CAMJJ ;  Q5HW83, KDSA_CAMJR ;  B8H5A9, KDSA_CAUCN ;
DR   Q9A8C5, KDSA_CAUCR ;  Q5L789, KDSA_CHLAB ;  Q824W7, KDSA_CHLCV ;
DR   Q252N1, KDSA_CHLFF ;  Q9PLS0, KDSA_CHLMU ;  Q46225, KDSA_CHLP6 ;
DR   Q9Z7I4, KDSA_CHLPN ;  B0B8N1, KDSA_CHLT2 ;  Q3KL39, KDSA_CHLTA ;
DR   B0BAB0, KDSA_CHLTB ;  P0CD74, KDSA_CHLTR ;  Q7NUF2, KDSA_CHRVO ;
DR   A8AG06, KDSA_CITK8 ;  Q47Y99, KDSA_COLP3 ;  B6J4X2, KDSA_COXB1 ;
DR   B6J3X3, KDSA_COXB2 ;  A9KDH6, KDSA_COXBN ;  Q83B43, KDSA_COXBU ;
DR   Q0KCE4, KDSA_CUPNH ;  Q473G6, KDSA_CUPPJ ;  B3R497, KDSA_CUPTR ;
DR   B8HXG7, KDSA_CYAP4 ;  Q47DI0, KDSA_DECAR ;  A9BN40, KDSA_DELAS ;
DR   B8F9X0, KDSA_DESAA ;  A8ZU09, KDSA_DESOH ;  Q6AQ79, KDSA_DESPS ;
DR   P61654, KDSA_DESVH ;  A1VDL1, KDSA_DESVV ;  A5EW23, KDSA_DICNV ;
DR   A7ZKY9, KDSA_ECO24 ;  B7UQA3, KDSA_ECO27 ;  B7MKB7, KDSA_ECO45 ;
DR   B7LGX6, KDSA_ECO55 ;  Q8XDE7, KDSA_ECO57 ;  B5YXN3, KDSA_ECO5E ;
DR   B7NUY1, KDSA_ECO7I ;  B7MTZ9, KDSA_ECO81 ;  B7LXX2, KDSA_ECO8A ;
DR   C4ZTQ6, KDSA_ECOBW ;  B1XAQ6, KDSA_ECODH ;  A7ZZF1, KDSA_ECOHS ;
DR   A1AAE2, KDSA_ECOK1 ;  Q0TIF5, KDSA_ECOL5 ;  Q8FHZ8, KDSA_ECOL6 ;
DR   B1ITN8, KDSA_ECOLC ;  P0A715, KDSA_ECOLI ;  B7N426, KDSA_ECOLU ;
DR   B6I9T0, KDSA_ECOSE ;  B1LH85, KDSA_ECOSM ;  Q1RCM3, KDSA_ECOUT ;
DR   C5B817, KDSA_EDWI9 ;  A4WBC2, KDSA_ENT38 ;  A7MKA7, KDSA_ENTS8 ;
DR   Q6D547, KDSA_ERWCT ;  B2VEI7, KDSA_ERWT9 ;  B7LSH5, KDSA_ESCF3 ;
DR   B0TZ07, KDSA_FRAP2 ;  Q2A271, KDSA_FRATH ;  B2SDK5, KDSA_FRATM ;
DR   A0Q5J1, KDSA_FRATN ;  Q8RE91, KDSA_FUSNN ;  B5E8N4, KDSA_GEOBB ;
DR   B3E467, KDSA_GEOLS ;  Q39W61, KDSA_GEOMG ;  B9M9Q6, KDSA_GEOSF ;
DR   P61655, KDSA_GEOSL ;  C6E0M6, KDSA_GEOSM ;  A5G5T2, KDSA_GEOUR ;
DR   Q0BTX5, KDSA_GRABC ;  Q7VMV6, KDSA_HAEDU ;  Q4QKR7, KDSA_HAEI8 ;
DR   A5UCE8, KDSA_HAEIE ;  A5UEF6, KDSA_HAEIG ;  P45251, KDSA_HAEIN ;
DR   B8F521, KDSA_HAEPS ;  Q0I3B9, KDSA_HAES1 ;  B0UUE2, KDSA_HAES2 ;
DR   Q2SKX1, KDSA_HAHCH ;  Q17Z24, KDSA_HELAH ;  Q7VK53, KDSA_HELHP ;
DR   B6JPA2, KDSA_HELP2 ;  Q1CVF2, KDSA_HELPH ;  Q9ZN55, KDSA_HELPJ ;
DR   B2UW07, KDSA_HELPS ;  P56060, KDSA_HELPY ;  A6SVC5, KDSA_JANMA ;
DR   B5XW55, KDSA_KLEP3 ;  A6TAN5, KDSA_KLEP7 ;  C1DCC2, KDSA_LARHH ;
DR   Q5X5Y5, KDSA_LEGPA ;  A5IB80, KDSA_LEGPC ;  Q5ZWA3, KDSA_LEGPH ;
DR   Q5WXA7, KDSA_LEGPL ;  B1Y4K5, KDSA_LEPCP ;  P61656, KDSA_LEPIC ;
DR   Q8F3J4, KDSA_LEPIN ;  A0L7X4, KDSA_MAGSM ;  Q65TB4, KDSA_MANSM ;
DR   A1TZ47, KDSA_MARAV ;  Q11HU7, KDSA_MESSB ;  Q604M5, KDSA_METCA ;
DR   Q1H010, KDSA_METFK ;  A2SJR1, KDSA_METPP ;  B1LZU2, KDSA_METRJ ;
DR   Q5F8Z0, KDSA_NEIG1 ;  B4RMD6, KDSA_NEIG2 ;  A9LZL2, KDSA_NEIM0 ;
DR   Q9JU48, KDSA_NEIMA ;  Q9JZ55, KDSA_NEIMB ;  A1KUB4, KDSA_NEIMF ;
DR   Q1QMJ3, KDSA_NITHX ;  Q3JCT2, KDSA_NITOC ;  Q3SRK0, KDSA_NITWN ;
DR   A6X0L7, KDSA_OCHA4 ;  Q6MEB3, KDSA_PARUW ;  P95514, KDSA_PASHA ;
DR   P57853, KDSA_PASMU ;  O50044, KDSA_PEA   ;  C6DHX7, KDSA_PECCP ;
DR   Q3A372, KDSA_PELCD ;  A1APG0, KDSA_PELPD ;  Q7N583, KDSA_PHOLL ;
DR   Q6LNB8, KDSA_PHOPR ;  A1VLH2, KDSA_POLNA ;  Q128E6, KDSA_POLSJ ;
DR   B4EVS0, KDSA_PROMH ;  Q7V4M4, KDSA_PROMM ;  Q48F78, KDSA_PSE14 ;
DR   A6V1F2, KDSA_PSEA7 ;  Q02RA8, KDSA_PSEAB ;  Q9ZFK4, KDSA_PSEAE ;
DR   Q1I645, KDSA_PSEE4 ;  Q4KHF7, KDSA_PSEF5 ;  C3K6H5, KDSA_PSEFS ;
DR   Q3IK90, KDSA_PSEHT ;  A4XWS2, KDSA_PSEMY ;  Q3KH93, KDSA_PSEPF ;
DR   B0KSB8, KDSA_PSEPG ;  B1J5Q5, KDSA_PSEPW ;  Q886M4, KDSA_PSESM ;
DR   Q4ZWQ9, KDSA_PSEU2 ;  A4VJU0, KDSA_PSEU5 ;  A1SV93, KDSA_PSYIN ;
DR   B2U9C1, KDSA_RALPJ ;  Q8Y0B7, KDSA_RALSO ;  Q98MZ6, KDSA_RHILO ;
DR   Q92Q99, KDSA_RHIME ;  Q7UQ25, KDSA_RHOBA ;  Q21V38, KDSA_RHOFD ;
DR   Q2IWC4, KDSA_RHOP2 ;  P61657, KDSA_RHOPA ;  Q136E1, KDSA_RHOPS ;
DR   B3Q6L6, KDSA_RHOPT ;  C3PMA0, KDSA_RICAE ;  A8GM05, KDSA_RICAH ;
DR   A8GUR8, KDSA_RICB8 ;  Q1RGT8, KDSA_RICBR ;  A8EXC8, KDSA_RICCK ;
DR   Q92JH7, KDSA_RICCN ;  Q4UN94, KDSA_RICFE ;  Q9ZE84, KDSA_RICPR ;
DR   C4K181, KDSA_RICPU ;  B0BW09, KDSA_RICRO ;  A8GQM3, KDSA_RICRS ;
DR   Q68XT6, KDSA_RICTY ;  B5F4I0, KDSA_SALA4 ;  A9MPA5, KDSA_SALAR ;
DR   Q57NN9, KDSA_SALCH ;  B5FU23, KDSA_SALDC ;  B5R3K3, KDSA_SALEP ;
DR   B5R6I4, KDSA_SALG2 ;  B4TKA0, KDSA_SALHS ;  B4SUF8, KDSA_SALNS ;
DR   Q5PNK8, KDSA_SALPA ;  A9MW08, KDSA_SALPB ;  C0Q363, KDSA_SALPC ;
DR   B5BI79, KDSA_SALPK ;  B4TXT8, KDSA_SALSV ;  P65216, KDSA_SALTI ;
DR   P65215, KDSA_SALTY ;  A8GDA7, KDSA_SERP5 ;  A1S8Q7, KDSA_SHEAM ;
DR   B8E809, KDSA_SHEB2 ;  A3D0G8, KDSA_SHEB5 ;  A6WSE4, KDSA_SHEB8 ;
DR   A9L2C8, KDSA_SHEB9 ;  Q12QR3, KDSA_SHEDO ;  Q087H9, KDSA_SHEFN ;
DR   B0TR22, KDSA_SHEHH ;  A3QH22, KDSA_SHELP ;  Q8EAR9, KDSA_SHEON ;
DR   A8H7A0, KDSA_SHEPA ;  A4Y3K6, KDSA_SHEPC ;  B8CKA0, KDSA_SHEPW ;
DR   A0KT94, KDSA_SHESA ;  A8FYY1, KDSA_SHESH ;  Q0HFD4, KDSA_SHESM ;
DR   Q0HYK2, KDSA_SHESR ;  A1RND3, KDSA_SHESW ;  B1KDA1, KDSA_SHEWM ;
DR   B2TZW3, KDSA_SHIB3 ;  Q31ZQ8, KDSA_SHIBS ;  Q32GZ2, KDSA_SHIDS ;
DR   Q0T5I0, KDSA_SHIF8 ;  P0A716, KDSA_SHIFL ;  Q3Z0T2, KDSA_SHISS ;
DR   Q2NRS7, KDSA_SODGM ;  B4SR83, KDSA_STRM5 ;  B2FK85, KDSA_STRMK ;
DR   Q31KV0, KDSA_SYNE7 ;  A0LK05, KDSA_SYNFM ;  Q5N119, KDSA_SYNP6 ;
DR   A5GI92, KDSA_SYNPW ;  Q7U9S3, KDSA_SYNPX ;  Q31G67, KDSA_THICR ;
DR   Q3SL44, KDSA_THIDA ;  B8GQ74, KDSA_THISH ;  C5CSV4, KDSA_VARPS ;
DR   A1WL88, KDSA_VEREI ;  A5CW13, KDSA_VESOH ;  A5F692, KDSA_VIBC3 ;
DR   Q9KQ29, KDSA_VIBCH ;  C3LPI0, KDSA_VIBCM ;  Q5E6S9, KDSA_VIBF1 ;
DR   B5FBX4, KDSA_VIBFM ;  A7MY69, KDSA_VIBHB ;  Q87RN0, KDSA_VIBPA ;
DR   B7VKH7, KDSA_VIBSL ;  Q8DFG3, KDSA_VIBVU ;  Q7MMY2, KDSA_VIBVY ;
DR   Q7MAF1, KDSA_WOLSU ;  Q8PLS2, KDSA_XANAC ;  Q3BUT2, KDSA_XANC5 ;
DR   Q4UTP0, KDSA_XANC8 ;  B0RUK2, KDSA_XANCB ;  Q8P9Z5, KDSA_XANCP ;
DR   Q2P1K6, KDSA_XANOM ;  B2SUA4, KDSA_XANOP ;  B2I936, KDSA_XYLF2 ;
DR   Q9PDU0, KDSA_XYLFA ;  B0U657, KDSA_XYLFM ;  Q87DY7, KDSA_XYLFT ;
DR   A1JRS8, KDSA_YERE8 ;  A7FIF7, KDSA_YERP3 ;  Q1C850, KDSA_YERPA ;
DR   B2K2Z4, KDSA_YERPB ;  Q8ZEX4, KDSA_YERPE ;  A9QZ04, KDSA_YERPG ;
DR   Q1CJJ7, KDSA_YERPN ;  A4TJN3, KDSA_YERPP ;  Q66AX1, KDSA_YERPS ;
DR   B1JM81, KDSA_YERPY ;
//
ID   2.5.1.56
DE   N-acetylneuraminate synthase.
AN   (NANA)condensing enzyme.
AN   N-acetylneuraminate pyruvate-lyase (pyruvate-phosphorylating).
AN   N-acetylneuraminic acid synthase.
AN   NeuAc synthase.
CA   Phosphoenolpyruvate + N-acetyl-D-mannosamine + H(2)O = phosphate +
CA   N-acetylneuraminate.
CC   -!- Formerly EC 4.1.3.19.
DR   Q9NR45, SIAS_HUMAN ;
//
ID   2.5.1.57
DE   N-acylneuraminate-9-phosphate synthase.
AN   N-acetylneuraminate 9-phosphate lyase.
AN   N-acetylneuraminate 9-phosphate sialic acid 9-phosphate synthase.
AN   N-acetylneuraminate 9-phosphate synthetase.
AN   N-acylneuraminate-9-phosphate pyruvate-lyase (pyruvate-phosphorylating).
AN   Sialic acid 9-phosphate synthetase.
CA   Phosphoenolpyruvate + N-acyl-D-mannosamine 6-phosphate + H(2)O =
CA   N-acylneuraminate 9-phosphate + phosphate.
CC   -!- Acts on N-glycoloyl and N-acetyl-derivatives.
CC   -!- Formerly EC 4.1.3.20.
DR   Q9NR45, SIAS_HUMAN ;
//
ID   2.5.1.58
DE   Protein farnesyltransferase.
AN   CAAX farnesyltransferase.
AN   FTase.
CA   Farnesyl diphosphate + protein-cysteine = S-farnesyl protein +
CA   diphosphate.
CF   Magnesium; Zinc.
CC   -!- This enzyme, along with EC 2.5.1.59 and EC 2.5.1.60, constitutes the
CC       protein prenyltransferase family of enzymes.
CC   -!- Catalyzes the formation of a thioether linkage between the C-1 of an
CC       isoprenyl group and a cysteine residue fourth from the C-terminus of
CC       the protein.
CC   -!- These protein acceptors have the C-terminal sequence CA(1)A(2)X,
CC       where the terminal residue, X, is preferably serine, methionine,
CC       alanine or glutamine; leucine makes the protein a substrate for
CC       EC 2.5.1.59.
CC   -!- The enzymes are relaxed in specificity for A(1), but cannot act if
CC       A(2) is aromatic.
CC   -!- Substrates of the prenyltransferases include Ras, Rho, Rab, other
CC       Ras-related small GTP-binding proteins, gamma-subunits of
CC       heterotrimeric G-proteins, nuclear lamins, centromeric proteins and
CC       many proteins involved in visual signal transduction.
PR   PROSITE; PDOC00703;
DR   Q9LX33, FNTA_ARATH ;  P29702, FNTA_BOVIN ;  Q9Y765, FNTA_CANAL ;
DR   Q54RT9, FNTA_DICDI ;  P49354, FNTA_HUMAN ;  Q61239, FNTA_MOUSE ;
DR   O24304, FNTA_PEA   ;  Q04631, FNTA_RAT   ;  O60052, FNTA_SCHPO ;
DR   P93227, FNTA_SOLLC ;  P29703, FNTA_YEAST ;  Q38920, FNTB_ARATH ;
DR   P49355, FNTB_BOVIN ;  Q55D51, FNTB_DICDI ;  P49356, FNTB_HUMAN ;
DR   Q8K2I1, FNTB_MOUSE ;  Q04903, FNTB_PEA   ;  Q02293, FNTB_RAT   ;
DR   O13782, FNTB_SCHPO ;  P22007, FNTB_YEAST ;
//
ID   2.5.1.59
DE   Protein geranylgeranyltransferase type I.
AN   GGTase-I.
AN   GGTaseI.
AN   Type I protein geranyl-geranyltransferase.
CA   Geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-
CA   protein + diphosphate.
CF   Zinc.
CC   -!- This enzyme, along with EC 2.5.1.58 and EC 2.5.1.60, constitutes the
CC       protein prenyltransferase family of enzymes.
CC   -!- Catalyzes the formation of a thioether linkage between the C-1 atom
CC       of the geranylgeranyl group and a cysteine residue fourth from the
CC       C-terminus of the protein.
CC   -!- These protein acceptors have the C-terminal sequence CA(1)A(2)X,
CC       where the terminal residue, X, is preferably leucine; serine,
CC       methionine, alanine or glutamine makes the protein a substrate for
CC       EC 2.5.1.58.
CC   -!- The enzymes are relaxed in specificity for A(1), but cannot act if
CC       A(2) is aromatic.
CC   -!- Known targets of this enzyme include most gamma-subunits of
CC       heterotrimeric G proteins and Ras-related GTPases such as members of
CC       the Ras and Rac/Rho families.
CC   -!- The Zn(2+) is required for peptide, but not for isoprenoid, substrate
CC       binding.
PR   PROSITE; PDOC00703;
DR   Q9LX33, FNTA_ARATH ;  P29702, FNTA_BOVIN ;  Q9Y765, FNTA_CANAL ;
DR   Q54RT9, FNTA_DICDI ;  P49354, FNTA_HUMAN ;  Q61239, FNTA_MOUSE ;
DR   O24304, FNTA_PEA   ;  Q04631, FNTA_RAT   ;  O60052, FNTA_SCHPO ;
DR   P93227, FNTA_SOLLC ;  P29703, FNTA_YEAST ;  Q5EAD5, PGTB1_BOVIN;
DR   Q55DA3, PGTB1_DICDI;  P53609, PGTB1_HUMAN;  Q8BUY9, PGTB1_MOUSE;
DR   P53610, PGTB1_RAT  ;  P32434, PGTB1_SCHPO;  P18898, PGTB1_YEAST;
//
ID   2.5.1.60
DE   Protein geranylgeranyltransferase type II.
AN   GGTaseII.
AN   Rab geranylgeranyltransferase.
AN   RabGGTase.
AN   Type II protein geranyl-geranyltransferase.
CA   Geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-
CA   protein + diphosphate.
CC   -!- This enzyme, along with EC 2.5.1.58 and EC 2.5.1.59, constitutes the
CC       protein prenyltransferase family of enzymes.
CC   -!- Attaches geranylgeranyl groups to two C-terminal cysteines in Ras-
CC       related GTPases of a single family, the Rab family (Ypt/Sec4 in lower
CC       eukaryotes) that terminate in XXCC, XCXC and CCXX motifs.
CC   -!- Reaction is entirely dependent on the Rab substrate being bound to
CC       Rab escort protein (REP).
CC   -!- Post-translational modification with the geranylgeranyl moiety is
CC       essential for Rab GTPases to be able to control the processes of
CC       membrane docking and fusion.
PR   PROSITE; PDOC00703;
DR   P41992, GGTB2_CAEEL;  Q5EA80, PGTA_BOVIN ;  O93829, PGTA_CANAL ;
DR   Q55DQ4, PGTA_DICDI ;  Q92696, PGTA_HUMAN ;  Q9JHK4, PGTA_MOUSE ;
DR   A5A779, PGTA_PIG   ;  Q5NVK5, PGTA_PONAB ;  Q08602, PGTA_RAT   ;
DR   O94412, PGTA_SCHPO ;  Q00618, PGTA_YEAST ;  Q5E9B3, PGTB2_BOVIN;
DR   O93830, PGTB2_CANAL;  B0G172, PGTB2_DICDI;  P53611, PGTB2_HUMAN;
DR   P53612, PGTB2_MOUSE;  Q08603, PGTB2_RAT  ;  P46960, PGTB2_SCHPO;
DR   P20133, PGTB2_YEAST;
//
ID   2.5.1.61
DE   Hydroxymethylbilane synthase.
AN   (4-(2-carboxyethyl)-3-(carboxymethyl)pyrrol-2-yl)methyltransferase
AN   (hydrolyzing).
AN   HMB-synthase.
AN   Porphobilinogen deaminase.
AN   Pre-uroporphyrinogen synthase.
AN   Uroporphyrinogen I synthase.
AN   Uroporphyrinogen I synthetase.
AN   Uroporphyrinogen synthase.
AN   Uroporphyrinogen synthetase.
CA   4 porphobilinogen + H(2)O = hydroxymethylbilane + 4 NH(3).
CF   Dipyrromethane.
CC   -!- The enzyme works by stepwise addition of pyrrolylmethyl groups until
CC       a hexapyrrole is present at the active center.
CC   -!- The terminal tetrapyrrole is then hydrolyzed to yield the product,
CC       leaving a cysteine-bound dipyrrole on which assembly continues.
CC   -!- In the presence of a second enzyme, EC 4.2.1.75, which is often
CC       called cosynthase, the product is cyclized to form uroporphyrinogen
CC       III.
CC   -!- If EC 4.2.1.75 is absent, the hydroxymethylbilane cyclizes
CC       spontaneously to form uroporphyrinogen I.
CC   -!- Formerly EC 4.3.1.8.
PR   PROSITE; PDOC00461;
DR   Q82E76, HEM31_STRAW;  Q9WX16, HEM31_STRCO;  Q82P95, HEM32_STRAW;
DR   Q9KY00, HEM32_STRCO;  Q6FFA9, HEM3_ACIAD ;  Q1INI6, HEM3_ACIBL ;
DR   A0LRF1, HEM3_ACIC1 ;  B7JBH8, HEM3_ACIF2 ;  B5ERN6, HEM3_ACIF5 ;
DR   A6VL87, HEM3_ACTSZ ;  Q9Y9J0, HEM3_AERPE ;  Q8UC46, HEM3_AGRT5 ;
DR   Q0VM28, HEM3_ALCBS ;  Q0A577, HEM3_ALHEH ;  B6EPK1, HEM3_ALISL ;
DR   A6TJD5, HEM3_ALKMQ ;  A8MGE4, HEM3_ALKOO ;  O66621, HEM3_AQUAE ;
DR   Q43316, HEM3_ARATH ;  A8ERI4, HEM3_ARCB4 ;  O29026, HEM3_ARCFU ;
DR   Q75DY0, HEM3_ASHGO ;  A7Z7A5, HEM3_BACA2 ;  C3P9E9, HEM3_BACAA ;
DR   C3L6Z5, HEM3_BACAC ;  A0RJ81, HEM3_BACAH ;  Q81LC7, HEM3_BACAN ;
DR   B7JQ57, HEM3_BACC0 ;  Q72ZW2, HEM3_BACC1 ;  B7IIX5, HEM3_BACC2 ;
DR   C1ETR0, HEM3_BACC3 ;  B7HE96, HEM3_BACC4 ;  B7HQM4, HEM3_BACC7 ;
DR   A7GTE5, HEM3_BACCN ;  B9IZ39, HEM3_BACCQ ;  Q817R0, HEM3_BACCR ;
DR   Q633Y0, HEM3_BACCZ ;  Q9K8G0, HEM3_BACHD ;  Q6HD62, HEM3_BACHK ;
DR   Q65GK1, HEM3_BACLD ;  A8FFV2, HEM3_BACP2 ;  Q5WEP5, HEM3_BACSK ;
DR   P16616, HEM3_BACSU ;  A9VIT8, HEM3_BACWK ;  Q1LU25, HEM3_BAUCH ;
DR   Q7VRM4, HEM3_BLOFL ;  Q491Z6, HEM3_BLOPB ;  Q7WKM1, HEM3_BORBR ;
DR   Q7W785, HEM3_BORPA ;  A9IKF3, HEM3_BORPD ;  Q7VVU9, HEM3_BORPE ;
DR   Q2KIN5, HEM3_BOVIN ;  C0ZAH1, HEM3_BREBN ;  B2S842, HEM3_BRUA1 ;
DR   Q2YLM5, HEM3_BRUA2 ;  Q57B08, HEM3_BRUAB ;  A9M8M2, HEM3_BRUC2 ;
DR   C0RFD1, HEM3_BRUMB ;  Q8YJB0, HEM3_BRUME ;  A5VSL5, HEM3_BRUO2 ;
DR   B0CID9, HEM3_BRUSI ;  Q8FYI6, HEM3_BRUSU ;  B8D8F3, HEM3_BUCA5 ;
DR   P57651, HEM3_BUCAI ;  B8D8B0, HEM3_BUCAT ;  B1JWR0, HEM3_BURCC ;
DR   B4E8C4, HEM3_BURCJ ;  Q0BCU9, HEM3_BURCM ;  A3MLK5, HEM3_BURM7 ;
DR   A2SAH5, HEM3_BURM9 ;  Q62LC0, HEM3_BURMA ;  A1V5U0, HEM3_BURMS ;
DR   A3NSN6, HEM3_BURP0 ;  Q3JUW3, HEM3_BURP1 ;  A3N700, HEM3_BURP6 ;
DR   B2JEN9, HEM3_BURP8 ;  B2T1D1, HEM3_BURPP ;  Q63W73, HEM3_BURPS ;
DR   Q2T071, HEM3_BURTA ;  A4JGV4, HEM3_BURVG ;  A8MDU3, HEM3_CALMQ ;
DR   A4XK06, HEM3_CALS8 ;  A7ZD37, HEM3_CAMC1 ;  A7GYU4, HEM3_CAMC5 ;
DR   A0RNT3, HEM3_CAMFF ;  A7I1S0, HEM3_CAMHC ;  A8FKW8, HEM3_CAMJ8 ;
DR   A7H4J7, HEM3_CAMJD ;  Q9PHW9, HEM3_CAMJE ;  A1VYQ4, HEM3_CAMJJ ;
DR   Q5HVM1, HEM3_CAMJR ;  B9KGA9, HEM3_CAMLR ;  O94048, HEM3_CANAL ;
DR   Q6FNR4, HEM3_CANGA ;  Q3ACT3, HEM3_CARHZ ;  B8GXG1, HEM3_CAUCN ;
DR   Q9ABZ8, HEM3_CAUCR ;  B0T287, HEM3_CAUSK ;  Q3AQF5, HEM3_CHLCH ;
DR   B3EIN1, HEM3_CHLL2 ;  Q9PK95, HEM3_CHLMU ;  P28464, HEM3_CHLP8 ;
DR   B3EPK0, HEM3_CHLPB ;  A1BHD6, HEM3_CHLPD ;  Q9Z9C9, HEM3_CHLPN ;
DR   B3QWI1, HEM3_CHLT3 ;  Q8KCJ4, HEM3_CHLTE ;  O84301, HEM3_CHLTR ;
DR   Q7P207, HEM3_CHRVO ;  Q97MU4, HEM3_CLOAB ;  A7FSG8, HEM3_CLOB1 ;
DR   C3L2Z3, HEM3_CLOB6 ;  A6LSY5, HEM3_CLOB8 ;  B2UXC4, HEM3_CLOBA ;
DR   B2TPD7, HEM3_CLOBB ;  A5I0B2, HEM3_CLOBH ;  C1FVB9, HEM3_CLOBJ ;
DR   B1IHD1, HEM3_CLOBK ;  A7GBW3, HEM3_CLOBL ;  B1KY15, HEM3_CLOBM ;
DR   B8I0Q8, HEM3_CLOCE ;  Q180R9, HEM3_CLOD6 ;  Q59293, HEM3_CLOJO ;
DR   B9DZL6, HEM3_CLOK1 ;  A0Q2B1, HEM3_CLONN ;  Q0TQG4, HEM3_CLOP1 ;
DR   Q8XKG4, HEM3_CLOPE ;  Q0ST16, HEM3_CLOPS ;  A3DIF0, HEM3_CLOTH ;
DR   Q48AW8, HEM3_COLP3 ;  C3PKG2, HEM3_CORA7 ;  Q6NJK0, HEM3_CORDI ;
DR   Q8FSF7, HEM3_COREF ;  A4QB59, HEM3_CORGB ;  Q8NT90, HEM3_CORGL ;
DR   B6J6K0, HEM3_COXB1 ;  B6J3T6, HEM3_COXB2 ;  A9KDC4, HEM3_COXBN ;
DR   A9N910, HEM3_COXBR ;  Q83A37, HEM3_COXBU ;  Q11XT5, HEM3_CYTH3 ;
DR   Q6BM23, HEM3_DEBHA ;  Q479S8, HEM3_DECAR ;  C1CYD9, HEM3_DEIDV ;
DR   Q1J288, HEM3_DEIGD ;  Q9RRY0, HEM3_DEIRA ;  C6BYB7, HEM3_DESAD ;
DR   B1I4L8, HEM3_DESAP ;  Q30Y29, HEM3_DESDG ;  B8G2M2, HEM3_DESHD ;
DR   Q24VC8, HEM3_DESHY ;  A8ZWG5, HEM3_DESOH ;  A4J6H7, HEM3_DESRM ;
DR   Q72AV0, HEM3_DESVH ;  B8DKW2, HEM3_DESVM ;  A1VCX6, HEM3_DESVV ;
DR   Q54P93, HEM3_DICDI ;  A5EW83, HEM3_DICNV ;  B7MH66, HEM3_ECO45 ;
DR   B7L959, HEM3_ECO55 ;  Q8XAP3, HEM3_ECO57 ;  B7NTE0, HEM3_ECO7I ;
DR   B7N295, HEM3_ECO81 ;  B7M603, HEM3_ECO8A ;  C4ZZ69, HEM3_ECOBW ;
DR   B1XAH2, HEM3_ECODH ;  Q8FBP1, HEM3_ECOL6 ;  P06983, HEM3_ECOLI ;
DR   B7NFA7, HEM3_ECOLU ;  B6I4E0, HEM3_ECOSE ;  Q3YSA8, HEM3_EHRCJ ;
DR   Q2GGC7, HEM3_EHRCR ;  A4WG12, HEM3_ENT38 ;  A7MQJ1, HEM3_ENTS8 ;
DR   P40129, HEM3_ERWCH ;  Q6CZG3, HEM3_ERWCT ;  B2VG55, HEM3_ERWT9 ;
DR   B7LU53, HEM3_ESCF3 ;  C4Z552, HEM3_EUBE2 ;  P13446, HEM3_EUGGR ;
DR   B1YJV1, HEM3_EXIS2 ;  C4L4J6, HEM3_EXISA ;  B0TW04, HEM3_FRAP2 ;
DR   Q14JI3, HEM3_FRAT1 ;  A7N9H6, HEM3_FRATF ;  Q2A5R3, HEM3_FRATH ;
DR   B2SE34, HEM3_FRATM ;  A0Q481, HEM3_FRATN ;  Q0BP15, HEM3_FRATO ;
DR   Q5NI31, HEM3_FRATT ;  A4IZY4, HEM3_FRATW ;  Q8RFP5, HEM3_FUSNN ;
DR   B5EBG8, HEM3_GEOBB ;  Q5KWK6, HEM3_GEOKA ;  B3E2H7, HEM3_GEOLS ;
DR   Q39QM7, HEM3_GEOMG ;  B9M416, HEM3_GEOSF ;  Q747I1, HEM3_GEOSL ;
DR   C6DYY8, HEM3_GEOSM ;  C5D5K7, HEM3_GEOSW ;  A4IRG5, HEM3_GEOTN ;
DR   A5GCW2, HEM3_GEOUR ;  Q7NGF7, HEM3_GLOVI ;  Q0I178, HEM3_HAES1 ;
DR   B0UWZ8, HEM3_HAES2 ;  Q2SQ70, HEM3_HAHCH ;  A1WVT9, HEM3_HALHL ;
DR   Q9HMY5, HEM3_HALSA ;  C4K4E3, HEM3_HAMD5 ;  Q17W61, HEM3_HELAH ;
DR   Q7VFE9, HEM3_HELHP ;  B6JKG8, HEM3_HELP2 ;  B5ZA04, HEM3_HELPG ;
DR   Q1CUR5, HEM3_HELPH ;  Q9ZMJ7, HEM3_HELPJ ;  B2US69, HEM3_HELPS ;
DR   P56140, HEM3_HELPY ;  P08397, HEM3_HUMAN ;  A2BL26, HEM3_HYPBU ;
DR   Q0BX92, HEM3_HYPNA ;  Q5QUS3, HEM3_IDILO ;  A8AAB4, HEM3_IGNH4 ;
DR   B5XYL1, HEM3_KLEP3 ;  A6TGI8, HEM3_KLEP7 ;  Q6CT60, HEM3_KLULA ;
DR   A5VM67, HEM3_LACRD ;  B2G9H4, HEM3_LACRJ ;  C1D679, HEM3_LARHH ;
DR   Q1MPL2, HEM3_LAWIP ;  Q5X1F2, HEM3_LEGPA ;  Q5ZRY6, HEM3_LEGPH ;
DR   Q5WT65, HEM3_LEGPL ;  Q6AHF1, HEM3_LEIXX ;  Q92BF8, HEM3_LISIN ;
DR   C1KVK3, HEM3_LISMC ;  Q71ZB2, HEM3_LISMF ;  B8DHJ2, HEM3_LISMH ;
DR   Q8Y6X5, HEM3_LISMO ;  A0AJ05, HEM3_LISW6 ;  B1HVD6, HEM3_LYSSC ;
DR   B9E743, HEM3_MACCJ ;  Q65VX7, HEM3_MANSM ;  A1TXW9, HEM3_MARAV ;
DR   Q8TT56, HEM3_METAC ;  Q46CH0, HEM3_METBF ;  Q12WM8, HEM3_METBU ;
DR   Q602K3, HEM3_METCA ;  Q1GXA1, HEM3_METFK ;  Q57989, HEM3_METJA ;
DR   Q8TXC8, HEM3_METKA ;  Q8PW57, HEM3_METMA ;  A4YD92, HEM3_METS5 ;
DR   O26960, HEM3_METTH ;  C5CB88, HEM3_MICLC ;  Q2RJ26, HEM3_MOOTA ;
DR   P22907, HEM3_MOUSE ;  A0QLI0, HEM3_MYCA1 ;  B1MHI5, HEM3_MYCA9 ;
DR   P64337, HEM3_MYCBO ;  A1KFY6, HEM3_MYCBP ;  C1AKJ0, HEM3_MYCBT ;
DR   A4T340, HEM3_MYCGI ;  Q49808, HEM3_MYCLE ;  B2HRJ2, HEM3_MYCMM ;
DR   Q73SS0, HEM3_MYCPA ;  A5TZP0, HEM3_MYCTA ;  P64336, HEM3_MYCTU ;
DR   A0PW29, HEM3_MYCUA ;  A1T3D3, HEM3_MYCVP ;  Q1D8Z8, HEM3_MYXXD ;
DR   B2A1G7, HEM3_NATTJ ;  Q9JVS4, HEM3_NEIMA ;  Q9K0P6, HEM3_NEIMB ;
DR   Q6MW51, HEM3_NEUCR ;  Q82WS2, HEM3_NITEU ;  Q1QQP5, HEM3_NITHX ;
DR   A9A1A1, HEM3_NITMS ;  A6Q3S1, HEM3_NITSB ;  Q3SVF3, HEM3_NITWN ;
DR   Q5YP70, HEM3_NOCFA ;  Q8YVU6, HEM3_NOSS1 ;  Q8CXC0, HEM3_OCEIH ;
DR   A6WXJ2, HEM3_OCHA4 ;  A5CDH4, HEM3_ORITB ;  B3CUP9, HEM3_ORITI ;
DR   Q6H6D2, HEM3_ORYSJ ;  O69110, HEM3_PAEMA ;  A1B853, HEM3_PARDP ;
DR   Q9CK24, HEM3_PASMU ;  Q43082, HEM3_PEA   ;  C6DHC2, HEM3_PECCP ;
DR   Q3A009, HEM3_PELCD ;  Q3B2Z5, HEM3_PELLD ;  B4SFI2, HEM3_PELPB ;
DR   A1AUE7, HEM3_PELPD ;  A5D3L5, HEM3_PELTS ;  B4RC21, HEM3_PHEZH ;
DR   Q7MYN1, HEM3_PHOLL ;  Q6L2G8, HEM3_PICTO ;  B4S922, HEM3_PROA2 ;
DR   Q6AB05, HEM3_PROAC ;  A3PBM0, HEM3_PROM0 ;  A2C0V4, HEM3_PROM1 ;
DR   A8G3L1, HEM3_PROM2 ;  A2C7L8, HEM3_PROM3 ;  A9BEB6, HEM3_PROM4 ;
DR   A2BVF7, HEM3_PROM5 ;  Q31C38, HEM3_PROM9 ;  Q7VD89, HEM3_PROMA ;
DR   B4F1X3, HEM3_PROMH ;  Q59684, HEM3_PROMI ;  Q7V697, HEM3_PROMM ;
DR   Q7V2I1, HEM3_PROMP ;  A2BPX7, HEM3_PROMS ;  Q46GS7, HEM3_PROMT ;
DR   A4SFJ8, HEM3_PROVI ;  Q15Z15, HEM3_PSEA6 ;  A6VE37, HEM3_PSEA7 ;
DR   B7V5F0, HEM3_PSEA8 ;  Q02EA3, HEM3_PSEAB ;  Q60169, HEM3_PSEAE ;
DR   Q1I316, HEM3_PSEE4 ;  Q4K3X3, HEM3_PSEF5 ;  C3K424, HEM3_PSEFS ;
DR   A5VWX3, HEM3_PSEP1 ;  Q3K4T0, HEM3_PSEPF ;  B0KH05, HEM3_PSEPG ;
DR   Q88RE5, HEM3_PSEPK ;  B1J1V2, HEM3_PSEPW ;  Q88B91, HEM3_PSESM ;
DR   Q500N6, HEM3_PSEU2 ;  A1T0R0, HEM3_PSYIN ;  Q8ZYW7, HEM3_PYRAE ;
DR   A4WN24, HEM3_PYRAR ;  A3MWV7, HEM3_PYRCJ ;  A1RQK2, HEM3_PYRIL ;
DR   Q8XWW3, HEM3_RALSO ;  P19356, HEM3_RAT   ;  Q98EI7, HEM3_RHILO ;
DR   Q92LH7, HEM3_RHIME ;  Q7UPN0, HEM3_RHOBA ;  Q21XQ9, HEM3_RHOFD ;
DR   C3PNS9, HEM3_RICAE ;  A8GNR5, HEM3_RICAH ;  A8GXC8, HEM3_RICB8 ;
DR   Q1RJN7, HEM3_RICBR ;  A8EYJ9, HEM3_RICCK ;  Q92HR5, HEM3_RICCN ;
DR   Q4ULA5, HEM3_RICFE ;  A8F1Y8, HEM3_RICM5 ;  Q9ZD77, HEM3_RICPR ;
DR   C4K265, HEM3_RICPU ;  B0BY00, HEM3_RICRO ;  A8GSI6, HEM3_RICRS ;
DR   Q68WR3, HEM3_RICTY ;  A7NKU8, HEM3_ROSCS ;  A5UU37, HEM3_ROSS1 ;
DR   Q1AUK3, HEM3_RUBXD ;  A1AX51, HEM3_RUTMC ;  A9MJ10, HEM3_SALAR ;
DR   B5FN93, HEM3_SALDC ;  Q5PKL7, HEM3_SALPA ;  C0Q3B3, HEM3_SALPC ;
DR   B5BIU8, HEM3_SALPK ;  B4TNV3, HEM3_SALSV ;  P0A1Q9, HEM3_SALTI ;
DR   P0A1Q8, HEM3_SALTY ;  Q09899, HEM3_SCHPO ;  A8G848, HEM3_SERP5 ;
DR   B8E879, HEM3_SHEB2 ;  A3D9Q4, HEM3_SHEB5 ;  A6WTG0, HEM3_SHEB8 ;
DR   A9L5G0, HEM3_SHEB9 ;  Q088L3, HEM3_SHEFN ;  B0TJ54, HEM3_SHEHH ;
DR   Q8E9H0, HEM3_SHEON ;  A8GZG4, HEM3_SHEPA ;  A4YBG2, HEM3_SHEPC ;
DR   A0KS60, HEM3_SHESA ;  A8G0W4, HEM3_SHESH ;  Q0HN99, HEM3_SHESM ;
DR   Q0HQI7, HEM3_SHESR ;  A1RPD7, HEM3_SHESW ;  B1KQC6, HEM3_SHEWM ;
DR   Q83PH4, HEM3_SHIFL ;  A9FDP9, HEM3_SORC5 ;  Q1GP41, HEM3_SPHAL ;
DR   A7X391, HEM3_STAA1 ;  A6U2D8, HEM3_STAA2 ;  Q2FG66, HEM3_STAA3 ;
DR   O34090, HEM3_STAA8 ;  A5ITJ5, HEM3_STAA9 ;  Q2YTB9, HEM3_STAAB ;
DR   Q5HFA2, HEM3_STAAC ;  A6QHK4, HEM3_STAAE ;  P64340, HEM3_STAAM ;
DR   P64341, HEM3_STAAN ;  Q6GG35, HEM3_STAAR ;  Q6G8Q5, HEM3_STAAS ;
DR   A8Z2J1, HEM3_STAAT ;  Q8NW74, HEM3_STAAW ;  B9DNE1, HEM3_STACT ;
DR   Q5HNN3, HEM3_STAEQ ;  Q8CNY8, HEM3_STAES ;  Q4L709, HEM3_STAHJ ;
DR   Q49YA2, HEM3_STAS1 ;  B4SJT8, HEM3_STRM5 ;  B2FI06, HEM3_STRMK ;
DR   A3CL78, HEM3_STRSV ;  Q30S90, HEM3_SULDN ;  C3MZR8, HEM3_SULIA ;
DR   C4KIZ9, HEM3_SULIK ;  C3MJ21, HEM3_SULIL ;  C3MYD9, HEM3_SULIM ;
DR   C3NF70, HEM3_SULIN ;  C3N841, HEM3_SULIY ;  A6Q7Y4, HEM3_SULNB ;
DR   Q980U4, HEM3_SULSO ;  Q976H1, HEM3_SULTO ;  Q2LQU2, HEM3_SYNAS ;
DR   Q31PM2, HEM3_SYNE7 ;  A0LN73, HEM3_SYNFM ;  Q7U5C2, HEM3_SYNPX ;
DR   A5GSE0, HEM3_SYNR3 ;  Q0I8I3, HEM3_SYNS3 ;  Q3AWQ4, HEM3_SYNS9 ;
DR   Q3ALS9, HEM3_SYNSC ;  Q0AZ43, HEM3_SYNWW ;  P73660, HEM3_SYNY3 ;
DR   Q9HKM5, HEM3_THEAC ;  Q8DIE4, HEM3_THEEB ;  Q47LA7, HEM3_THEFY ;
DR   B1YDP0, HEM3_THENV ;  Q72H57, HEM3_THET2 ;  Q5SLE8, HEM3_THET8 ;
DR   Q97B26, HEM3_THEVO ;  Q31JG5, HEM3_THICR ;  Q3SFT5, HEM3_THIDA ;
DR   B8GSU8, HEM3_THISH ;  Q0W5T2, HEM3_UNCMA ;  A5CW34, HEM3_VESOH ;
DR   Q9KVM1, HEM3_VIBCH ;  Q5E8T5, HEM3_VIBF1 ;  B5FF97, HEM3_VIBFM ;
DR   A7MXU9, HEM3_VIBHB ;  Q87KI9, HEM3_VIBPA ;  B7VMD9, HEM3_VIBSL ;
DR   Q8DD85, HEM3_VIBVU ;  Q7MQC7, HEM3_VIBVY ;  Q7M8L2, HEM3_WOLSU ;
DR   C0R2M3, HEM3_WOLWR ;  Q8PPR3, HEM3_XANAC ;  Q3BXV3, HEM3_XANC5 ;
DR   Q4UYZ4, HEM3_XANC8 ;  B0RNI9, HEM3_XANCB ;  Q8P536, HEM3_XANCP ;
DR   Q2NYU4, HEM3_XANOM ;  B2SMV3, HEM3_XANOP ;  Q5GVL2, HEM3_XANOR ;
DR   B2I5K8, HEM3_XYLF2 ;  Q9PCX7, HEM3_XYLFA ;  B0U2W8, HEM3_XYLFM ;
DR   Q87CC9, HEM3_XYLFT ;  Q6C097, HEM3_YARLI ;  P28789, HEM3_YEAST ;
DR   A1JI86, HEM3_YERE8 ;  P30527, HEM3_YERIN ;  A7FD67, HEM3_YERP3 ;
DR   Q1CBN1, HEM3_YERPA ;  B2K065, HEM3_YERPB ;  P46355, HEM3_YERPE ;
DR   A9R8K0, HEM3_YERPG ;  Q1CNI3, HEM3_YERPN ;  A4TRA8, HEM3_YERPP ;
DR   Q66G00, HEM3_YERPS ;  B1JPE6, HEM3_YERPY ;
//
ID   2.5.1.62
DE   Chlorophyll synthase.
CA   Chlorophyllide a + phytyl diphosphate = chlorophyll a + diphosphate.
CF   Magnesium.
CC   -!- The enzyme is modified by binding of the first substrate, phytyl
CC       diphosphate, before reaction of the modified enzyme with the second
CC       substrate, chlorophyllide a, can occur.
CC   -!- The reaction also occurs when phytyl diphosphate is replaced by
CC       geranylgeranyl diphosphate.
DR   Q38833, CHLG_ARATH ;  Q9M3W5, CHLG_AVESA ;  Q5W6H5, CHLG_ORYSJ ;
//
ID   2.5.1.63
DE   Adenosyl-fluoride synthase.
AN   Fluorinase.
CA   S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine +
CA   L-methionine.
//
ID   2.5.1.64
DE   Transferred entry: 2.2.1.9 and 4.2.99.20.
//
ID   2.5.1.65
DE   O-phosphoserine sulfhydrylase.
AN   O-phosphoserine(thiol)-lyase.
CA   O-phospho-L-serine + H(2)S = L-cysteine + phosphate.
CF   Pyridoxal 5'-phosphate.
CC   -!- The enzyme from Aeropyrum pernix acts on both O-phospho-L-serine and
CC       O(3)-acetyl-L-serine, in contrast with EC 2.5.1.47, which acts only
CC       on O(3)-acetyl-L-serine.
DR   P63874, CYSM_MYCBO ;  P63873, CYSM_MYCTU ;  Q9YBL2, CYSO_AERPE ;
//
ID   2.5.1.66
DE   N(2)-(2-carboxyethyl)arginine synthase.
AN   CEA synthetase.
AN   CEAS.
AN   N(2)-(2-carboxyethyl)arginine synthetase.
CA   D-glyceraldehyde 3-phosphate + L-arginine = N(2)-(2-carboxyethyl)-L-
CA   arginine + phosphate.
CC   -!- Requires thiamine diphosphate and catalyzes the first step in the
CC       clavulanic-acid biosynthesis pathway.
CC   -!- The 2-hydroxy-3-oxo group transferred from glyceraldehyde 3-phosphate
CC       is isomerized during transfer to form the 2-carboxyethyl group.
//
ID   2.5.1.67
DE   Chrysanthemyl diphosphate synthase.
AN   CPPase.
CA   2 dimethylallyl diphosphate = diphosphate + chrysanthemyl diphosphate.
CF   Manganese or magnesium.
CC   -!- Chrysanthemyl diphosphate is a monoterpene with a non-head-to-tail
CC       linkage; it is unlike most monoterpenoids, which are derived from
CC       geranyl diphosphate and have isoprene units that are linked head-
CC       to-tail.
CC   -!- The mechanism of its formation is similar to that of the early steps
CC       of squalene and phytoene biosynthesis.
CC   -!- Chrysanthemyl diphosphate is the precursor of chrysanthemic acid,
CC       the acid half of the pyrethroid insecticides found in chrysanthemums.
DR   Q7XYS8, CHRDS_ARTSI;  P0C565, CPPAS_TANCI;
//
ID   2.5.1.68
DE   (2Z,6E)-farnesyl diphosphate synthase.
AN   (Z)-farnesyl diphosphate synthase.
AN   Z-farnesyl diphosphate synthase.
CA   Geranyl diphosphate + isopentenyl diphosphate = diphosphate + (2Z,6E)-
CA   farnesyl diphosphate.
CF   Manganese or magnesium.
CC   -!- The product of this reaction is an intermediate in the synthesis of
CC       decaprenyl phosphate, which plays a central role in the biosynthesis
CC       of most features of the mycobacterial cell wall, including
CC       peptidoglycan, linker unit galactan and arabinan.
CC   -!- Neryl diphosphate can also act as substrate.
DR   Q7U0P8, ZFPP_MYCBO ;  Q9CB36, ZFPP_MYCLE ;  O53434, ZFPP_MYCTU ;
//
ID   2.5.1.69
DE   Lavandulyl diphosphate synthase.
AN   FDS-5.
CA   2 dimethylallyl diphosphate = diphosphate + lavandulyl diphosphate.
CC   -!- Lavandulyl diphosphate is a monoterpene with a non-head-to-tail
CC       linkage; it is unlike most monoterpenoids, which are derived from
CC       geranyl diphosphate and have isoprene units that are linked head-
CC       to-tail.
CC   -!- When this enzyme is incubated with dimethylallyl diphosphate and
CC       isopentenyl diphosphate, it also forms the regular monoterpene
CC       geranyl diphosphate.
CC   -!- The enzyme from Artemisia tridentata (big sagebrush) forms both
CC       lavandulyl diphosphate and chrysanthemyl diphosphate (see
CC       EC 2.5.1.67) when dimethylally diphosphate is the sole substrate.
DR   Q7XYS8, CHRDS_ARTSI;
//
ID   2.5.1.70
DE   Naringenin 8-dimethylallyltransferase.
AN   N8DT.
CA   Dimethylallyl diphosphate + (-)-(2S)-naringenin = diphosphate +
CA   sophoraflavanone B.
CF   Magnesium.
CC   -!- In addition to naringenin, the enzyme can prenylate several other
CC       flavanones at the C-8 position, but more slowly.
CC   -!- Along with EC 1.14.13.103 and EC 2.5.1.71, this enzyme forms part of
CC       the sophoraflavanone-G biosynthesis pathway.
//
ID   2.5.1.71
DE   Leachianone-G 2''-dimethylallyltransferase.
AN   Leachianone G 2''-dimethylallyltransferase.
AN   LG 2''-dimethylallyltransferase.
AN   LGDT.
CA   Dimethylallyl diphosphate + leachianone G = diphosphate +
CA   sophoraflavanone G.
CC   -!- The reaction forms the lavandulyl sidechain of sophoraflavanone G by
CC       transferring a dimethylallyl group to the 2'' position of another
CC       dimethylallyl group attached at postiion 8 of leachianone G.
CC   -!- The enzyme is specific for dimethylallyl diphosphate as the prenyl
CC       donor, as it cannot be replaced by isopentenyl diphosphate or geranyl
CC       diphosphate.
CC   -!- Euchrenone a(7) (a 5-deoxy derivative of leachianone G) and
CC       kenusanone I (a 7-methoxy derivative of leachianone G) can also act
CC       as substrates, but more slowly.
CC   -!- Along with EC 1.14.13.103 and EC 2.5.1.70, this enzyme forms part of
CC       the sophoraflavanone-G biosynthesis pathway.
//
ID   2.5.1.72
DE   Quinolinate synthase.
AN   Quinolinate synthetase.
CA   Glycerone phosphate + iminosuccinate = pyridine-2,3-dicarboxylate +
CA   2 H(2)O + phosphate.
CF   Iron-sulfur.
CC   -!- Quinolinate synthase catalyzes the second step in the de novo
CC       biosynthesis of NAD(+) from aspartate in some bacteria, with
CC       EC 1.4.3.16 catalyzing the first step and EC 2.4.2.19 the third step.
CC   -!- In Escherichia coli, two of the residues that are involved in the
CC       [4Fe-4S] cluster binding appear to undergo reversible disulfide-bond
CC       formation that regulates the activity of the enzyme.
DR   Q8TS46, NADA1_METAC;  Q98AV7, NADA1_RHILO;  Q8TME2, NADA2_METAC;
DR   Q982F2, NADA2_RHILO;  C1F557, NADA_ACIC5 ;  Q8U8J3, NADA_AGRT5 ;
DR   A6TJ92, NADA_ALKMQ ;  B9MRK8, NADA_ANATD ;  Q3MBM3, NADA_ANAVT ;
DR   B7GIR9, NADA_ANOFW ;  O67730, NADA_AQUAE ;  A7Z774, NADA_BACA2 ;
DR   C3P9B5, NADA_BACAA ;  C3L6V9, NADA_BACAC ;  A0RJ35, NADA_BACAH ;
DR   Q81LG1, NADA_BACAN ;  B7JQ14, NADA_BACC0 ;  Q730A4, NADA_BACC1 ;
DR   B7IIT9, NADA_BACC2 ;  C1ETM6, NADA_BACC3 ;  B7HE61, NADA_BACC4 ;
DR   B7HQI6, NADA_BACC7 ;  A7GTA8, NADA_BACCN ;  B9IZ04, NADA_BACCQ ;
DR   Q817V8, NADA_BACCR ;  Q634B5, NADA_BACCZ ;  Q9KDJ3, NADA_BACHD ;
DR   Q6HD97, NADA_BACHK ;  Q65GN4, NADA_BACLD ;  A8FFS2, NADA_BACP2 ;
DR   Q5WHS1, NADA_BACSK ;  Q9KWZ1, NADA_BACSU ;  A9VIQ3, NADA_BACWK ;
DR   B1YV98, NADA_BURA4 ;  Q1BUA7, NADA_BURCA ;  B1JXB7, NADA_BURCC ;
DR   A0K9S9, NADA_BURCH ;  Q0BCL4, NADA_BURCM ;  A3MN00, NADA_BURM7 ;
DR   A2S4Z4, NADA_BURM9 ;  Q62HM0, NADA_BURMA ;  A1V6U5, NADA_BURMS ;
DR   A3NSD8, NADA_BURP0 ;  A3N6Q4, NADA_BURP6 ;  B2JDZ5, NADA_BURP8 ;
DR   Q63WH7, NADA_BURPS ;  Q39DN4, NADA_BURS3 ;  Q2T0G7, NADA_BURTA ;
DR   A4XKC7, NADA_CALS8 ;  B8H2F3, NADA_CAUCN ;  Q9A4C4, NADA_CAUCR ;
DR   B3QM61, NADA_CHLP8 ;  A1BEP5, NADA_CHLPD ;  B3QS01, NADA_CHLT3 ;
DR   Q8KEW2, NADA_CHLTE ;  Q97K94, NADA_CLOAB ;  B8I2A5, NADA_CLOCE ;
DR   Q185P4, NADA_CLOD6 ;  B9DZP5, NADA_CLOK1 ;  A5N670, NADA_CLOK5 ;
DR   A0Q1U7, NADA_CLONN ;  Q0TU51, NADA_CLOP1 ;  Q8XNE3, NADA_CLOPE ;
DR   Q0SVZ5, NADA_CLOPS ;  Q8NRI0, NADA_CORGL ;  B8HNE6, NADA_CYAP4 ;
DR   B7KBV9, NADA_CYAP7 ;  B7JYJ9, NADA_CYAP8 ;  P31179, NADA_CYAPA ;
DR   Q3Z663, NADA_DEHE1 ;  A5FPF7, NADA_DEHSB ;  Q3ZW59, NADA_DEHSC ;
DR   B1I1G4, NADA_DESAP ;  A7ZJC5, NADA_ECO24 ;  B7ULM3, NADA_ECO27 ;
DR   B7MGK7, NADA_ECO45 ;  B7LAF1, NADA_ECO55 ;  Q8X963, NADA_ECO57 ;
DR   B7NMW2, NADA_ECO7I ;  B7MPN4, NADA_ECO81 ;  B7M6B3, NADA_ECO8A ;
DR   C4ZXS1, NADA_ECOBW ;  B1X6S4, NADA_ECODH ;  A7ZY06, NADA_ECOHS ;
DR   A1A8Z3, NADA_ECOK1 ;  Q0TJV1, NADA_ECOL5 ;  Q8FJS7, NADA_ECOL6 ;
DR   B1IXY6, NADA_ECOLC ;  P11458, NADA_ECOLI ;  B7N9Z2, NADA_ECOLU ;
DR   B6I7Q4, NADA_ECOSE ;  B1LM42, NADA_ECOSM ;  Q1REI1, NADA_ECOUT ;
DR   Q3YT89, NADA_EHRCJ ;  O05104, NADA_EHRCR ;  A4W892, NADA_ENT38 ;
DR   Q6D7E7, NADA_ERWCT ;  B2VBT3, NADA_ERWT9 ;  B7LKL5, NADA_ESCF3 ;
DR   Q8R6C9, NADA_FUSNN ;  B5EC56, NADA_GEOBB ;  Q5KWQ2, NADA_GEOKA ;
DR   Q39PS5, NADA_GEOMG ;  Q74H71, NADA_GEOSL ;  C6E657, NADA_GEOSM ;
DR   C5D5F6, NADA_GEOSW ;  A4IRC0, NADA_GEOTN ;  A5GDD6, NADA_GEOUR ;
DR   Q2SCM1, NADA_HAHCH ;  Q5UXB3, NADA_HALMA ;  B0R6K3, NADA_HALS3 ;
DR   Q9HNZ1, NADA_HALSA ;  Q1CRQ2, NADA_HELPH ;  Q9ZJN1, NADA_HELPJ ;
DR   O25910, NADA_HELPY ;  A9B1Q2, NADA_HERA2 ;  A4G431, NADA_HERAR ;
DR   Q72N73, NADA_LEPIC ;  Q8F8D9, NADA_LEPIN ;  Q929Z0, NADA_LISIN ;
DR   C1KWW9, NADA_LISMC ;  Q71XZ5, NADA_LISMF ;  B8DBQ6, NADA_LISMH ;
DR   Q8Y5N2, NADA_LISMO ;  B1HY35, NADA_LYSSC ;  A1U1B1, NADA_MARAV ;
DR   A7IA72, NADA_METB6 ;  Q46BD7, NADA_METBF ;  Q57850, NADA_METJA ;
DR   Q8TZ66, NADA_METKA ;  Q8PV98, NADA_METMA ;  O27855, NADA_METTH ;
DR   B0JLU4, NADA_MICAN ;  A0QHI6, NADA_MYCA1 ;  P65498, NADA_MYCBO ;
DR   A1KJ10, NADA_MYCBP ;  C1ANL6, NADA_MYCBT ;  A4T9M4, NADA_MYCGI ;
DR   B8ZR90, NADA_MYCLB ;  Q49622, NADA_MYCLE ;  Q740Q3, NADA_MYCPA ;
DR   A3Q137, NADA_MYCSJ ;  A1UHL4, NADA_MYCSK ;  Q1B7F9, NADA_MYCSS ;
DR   A5U2V0, NADA_MYCTA ;  P65497, NADA_MYCTU ;  Q5F6I7, NADA_NEIG1 ;
DR   A9M2J9, NADA_NEIM0 ;  Q9JSX6, NADA_NEIMA ;  Q9K105, NADA_NEIMB ;
DR   A1KVN9, NADA_NEIMF ;  A1SLG6, NADA_NOCSJ ;  B2IYC1, NADA_NOSP7 ;
DR   Q8YN94, NADA_NOSS1 ;  C6DCF2, NADA_PECCP ;  A1AUZ4, NADA_PELPD ;
DR   Q7N6S3, NADA_PHOLL ;  Q6LP50, NADA_PHOPR ;  B4S6K6, NADA_PROA2 ;
DR   A2C9Z7, NADA_PROM3 ;  Q7V7S6, NADA_PROMM ;  A6V9L0, NADA_PSEA7 ;
DR   Q02IG9, NADA_PSEAB ;  Q9I4W9, NADA_PSEAE ;  Q1I6G9, NADA_PSEE4 ;
DR   Q3IJ06, NADA_PSEHT ;  A4XRT1, NADA_PSEMY ;  A5VZW1, NADA_PSEP1 ;
DR   Q3K7X0, NADA_PSEPF ;  B0KTH8, NADA_PSEPG ;  Q87Y50, NADA_PSESM ;
DR   Q4ZW81, NADA_PSEU2 ;  Q9V2R2, NADA_PYRAB ;  Q8ZTS6, NADA_PYRAE ;
DR   Q8TZL3, NADA_PYRFU ;  O57767, NADA_PYRHO ;  Q5JFX9, NADA_PYRKO ;
DR   B2UAP5, NADA_RALPJ ;  Q8XWM5, NADA_RALSO ;  Q92R33, NADA_RHIME ;
DR   C3M8U4, NADA_RHISN ;  Q7UNR5, NADA_RHOBA ;  B5F034, NADA_SALA4 ;
DR   Q57RK0, NADA_SALCH ;  B5QX27, NADA_SALEP ;  B5R6A2, NADA_SALG2 ;
DR   B4TC11, NADA_SALHS ;  B4SZF9, NADA_SALNS ;  Q5PCN5, NADA_SALPA ;
DR   B5BC59, NADA_SALPK ;  Q8Z8B8, NADA_SALTI ;  P24519, NADA_SALTY ;
DR   A8GB96, NADA_SERP5 ;  Q8EEN5, NADA_SHEON ;  A0KX39, NADA_SHESA ;
DR   Q0HIL9, NADA_SHESM ;  Q0HVB6, NADA_SHESR ;  B2TUY1, NADA_SHIB3 ;
DR   Q324G9, NADA_SHIBS ;  Q32IH8, NADA_SHIDS ;  Q0T6Y0, NADA_SHIF8 ;
DR   Q93CP9, NADA_SHIFL ;  A6U7C5, NADA_SINMW ;  Q2NUL1, NADA_SODGM ;
DR   B9DMZ6, NADA_STACT ;  Q9F364, NADA_STRCO ;  Q97ZC4, NADA_SULSO ;
DR   B2V9E3, NADA_SULSY ;  Q972D1, NADA_SULTO ;  Q9L790, NADA_SYNE7 ;
DR   Q5N5W8, NADA_SYNP6 ;  P74578, NADA_SYNY3 ;  Q8DM90, NADA_THEEB ;
DR   C5A4G1, NADA_THEGJ ;  Q9X1X7, NADA_THEMA ;  B9K7I7, NADA_THENN ;
DR   B6YVQ4, NADA_THEON ;  A5ILT8, NADA_THEP1 ;  B1LB31, NADA_THESQ ;
DR   Q72JZ8, NADA_THET2 ;  Q5SJM4, NADA_THET8 ;  B5YJJ2, NADA_THEYD ;
DR   Q112B6, NADA_TRIEI ;  A5F769, NADA_VIBC3 ;  Q9KR14, NADA_VIBCH ;
DR   C3LND6, NADA_VIBCM ;  A7MTL8, NADA_VIBHB ;  Q87QT6, NADA_VIBPA ;
DR   Q8DAM0, NADA_VIBVU ;  Q7MJ90, NADA_VIBVY ;  Q8D343, NADA_WIGBR ;
DR   Q9PC58, NADA_XYLFA ;  Q87D18, NADA_XYLFT ;  A1JRP2, NADA_YERE8 ;
DR   A7FKQ0, NADA_YERP3 ;  Q1CAE9, NADA_YERPA ;  B2K8Q8, NADA_YERPB ;
DR   Q8ZGY8, NADA_YERPE ;  A9R3A9, NADA_YERPG ;  Q1CFN2, NADA_YERPN ;
DR   A4TNS5, NADA_YERPP ;  Q66D87, NADA_YERPS ;  B1JSU6, NADA_YERPY ;
//
ID   2.5.1.73
DE   O-phospho-L-seryl-tRNA:Cys-tRNA synthase.
AN   Sep-tRNA:Cys-tRNA synthase.
AN   SepCysS.
CA   O-phospho-L-seryl-tRNA(Cys) + sulfide = L-cysteinyl-tRNA(Cys) +
CA   phosphate.
CC   -!- In organisms like Archaeoglobus fulgidus lacking EC 6.1.1.16 for the
CC       direct Cys-tRNA(Cys) formation, Cys-tRNA(Cys) is produced by an
CC       indirect pathway, in which EC 6.1.1.27 ligates O-phosphoserine to
CC       tRNA(Cys), and EC 2.5.1.73 converts the produced O-phospho-L-seryl-
CC       tRNA(Cys) to Cys-tRNA(Cys).
CC   -!- The SepRS/SepCysS pathway is the sole route for cysteine biosynthesis
CC       in the organism.
CC   -!- Methanosarcina mazei can use both pathways, the direct route using
CC       EC 6.1.1.16 and the indirect pathway with EC 6.1.1.27 and
CC       EC 2.5.1.73.
CC   -!- Formerly EC 2.5.1.n3.
DR   O30207, SPSS1_ARCFU;  A7I757, SPSS1_METB6;  Q12XS4, SPSS1_METBU;
DR   Q2FLN5, SPSS1_METHJ;  A2SQB8, SPSS1_METLZ;  Q0W2L3, SPSS1_UNCMA;
DR   O30056, SPSS2_ARCFU;  A7I9Z8, SPSS2_METB6;  Q12W26, SPSS2_METBU;
DR   Q2FTY4, SPSS2_METHJ;  A2SSS7, SPSS2_METLZ;  Q0W486, SPSS2_UNCMA;
DR   A6UUU3, SPSS_META3 ;  Q8TSS3, SPSS_METAC ;  Q46C09, SPSS_METBF ;
DR   Q59072, SPSS_METJA ;  Q8TYR3, SPSS_METKA ;  A4FWT8, SPSS_METM5 ;
DR   A9AA73, SPSS_METM6 ;  A6VGH9, SPSS_METM7 ;  Q8PVS9, SPSS_METMA ;
DR   A3CVZ3, SPSS_METMJ ;  Q6LXV6, SPSS_METMP ;  O27139, SPSS_METTH ;
DR   A0B5D0, SPSS_METTP ;  A6UPN9, SPSS_METVS ;
//
ID   2.5.1.74
DE   1,4-dihydroxy-2-naphthoate polyprenyltransferase.
CA   An all-trans-polyprenyl diphosphate + 1,4-dihydroxy-2-naphthoate =
CA   a demethylmenaquinol + diphosphate + CO(2).
CC   -!- This enzyme catalyzes a step in the synthesis of menaquinone,
CC       in which the prenyl chain synthesized by polyprenyl diphosphate
CC       synthase is transferred to 1,4-dihydroxy-2-naphthoate (DHNA).
CC   -!- The bacterial enzyme is an inner membrane protein, with the
CC       C-terminus located in the periplasm.
CC   -!- It is highly specific for DHNA but not for a specific length of the
CC       prenyl chain.
DR   Q0WUA3, MENA_ARATH ;  P39582, MENA_BACSU ;  P32166, MENA_ECOLI ;
DR   P44739, MENA_HAEIN ;  P65651, MENA_MYCBO ;  O07134, MENA_MYCLE ;
DR   P65650, MENA_MYCTU ;  P73962, MENA_SYNY3 ;
//
ID   2.5.1.75
DE   tRNA dimethylallyltransferase.
AN   IPP transferase.
AN   tRNA prenyltransferase.
CA   Dimethylallyl diphosphate + tRNA = diphosphate + tRNA containing
CA   6-dimethylallyladenosine.
CC   -!- Formerly known as tRNA isopentenyltransferase (EC 2.5.1.8), but it is
CC       now known that dimethylallyl diphosphate, rather than isopentenyl
CC       diphosphate, is the substrate.
CC   -!- Formerly EC 1.8.6.1 and EC 2.5.1.8.
DR   Q9ZUX7, IPT2_ARATH ;  Q9C5J6, IPT9_ARATH ;  B6YQT8, MIAA1_AZOPC;
DR   Q5LH18, MIAA1_BACFN;  Q64XX2, MIAA1_BACFR;  Q8A018, MIAA1_BACTN;
DR   A6KWL7, MIAA1_BACV8;  B5EGD5, MIAA1_GEOBB;  B3E5Z1, MIAA1_GEOLS;
DR   B9M876, MIAA1_GEOSF;  A5GE43, MIAA1_GEOUR;  Q2SJX0, MIAA1_HAHCH;
DR   B2HGM7, MIAA1_MYCMM;  A0PT81, MIAA1_MYCUA;  A6L8Q7, MIAA1_PARD8;
DR   Q3A503, MIAA1_PELCD;  A1AT90, MIAA1_PELPD;  B2RKS4, MIAA1_PORG3;
DR   Q7MAW8, MIAA1_PORGI;  A8FRD4, MIAA1_SHESH;  Q2LTI8, MIAA1_SYNAS;
DR   Q73RN1, MIAA1_TREDE;  B6YRM5, MIAA2_AZOPC;  Q5LGQ7, MIAA2_BACFN;
DR   Q64XK5, MIAA2_BACFR;  Q89ZQ3, MIAA2_BACTN;  A6L683, MIAA2_BACV8;
DR   B5E9C1, MIAA2_GEOBB;  B3E590, MIAA2_GEOLS;  B9M3M9, MIAA2_GEOSF;
DR   A5GEV6, MIAA2_GEOUR;  Q2SBC1, MIAA2_HAHCH;  B2HL15, MIAA2_MYCMM;
DR   A0PTG1, MIAA2_MYCUA;  A6LDS8, MIAA2_PARD8;  Q39ZX2, MIAA2_PELCD;
DR   A1AU18, MIAA2_PELPD;  B2RLA0, MIAA2_PORG3;  Q7MAW6, MIAA2_PORGI;
DR   A8FZE2, MIAA2_SHESH;  Q2LUR0, MIAA2_SYNAS;  Q73MR1, MIAA2_TREDE;
DR   B0CG28, MIAA_ACAM1 ;  A9NGL4, MIAA_ACHLI ;  A1TLP7, MIAA_ACIAC ;
DR   Q6F9W1, MIAA_ACIAD ;  B7H141, MIAA_ACIB3 ;  B7IAP6, MIAA_ACIB5 ;
DR   B2HTT5, MIAA_ACIBC ;  Q1IHU1, MIAA_ACIBL ;  B0VM64, MIAA_ACIBS ;
DR   A3M6J6, MIAA_ACIBT ;  B0V7B1, MIAA_ACIBY ;  A0LUZ6, MIAA_ACIC1 ;
DR   A5G2E2, MIAA_ACICJ ;  B9MCW1, MIAA_ACIET ;  B7JC25, MIAA_ACIF2 ;
DR   B5EJE8, MIAA_ACIF5 ;  A1WAG1, MIAA_ACISJ ;  A3N3P8, MIAA_ACTP2 ;
DR   B3H330, MIAA_ACTP7 ;  B0BTY5, MIAA_ACTPJ ;  A6VN09, MIAA_ACTSZ ;
DR   A0KGS0, MIAA_AERHH ;  A4SR26, MIAA_AERS4 ;  B9JGK2, MIAA_AGRRK ;
DR   P0A3Q5, MIAA_AGRT5 ;  B9JXP7, MIAA_AGRVS ;  B2UPK2, MIAA_AKKM8 ;
DR   Q0VME6, MIAA_ALCBS ;  Q0AB61, MIAA_ALHEH ;  B6EMQ8, MIAA_ALISL ;
DR   A6TR77, MIAA_ALKMQ ;  A8MFD2, MIAA_ALKOO ;  B4S1F8, MIAA_ALTMD ;
DR   B3ES47, MIAA_AMOA5 ;  B8JBF4, MIAA_ANAD2 ;  Q2II09, MIAA_ANADE ;
DR   A7HCR8, MIAA_ANADF ;  B9KIU4, MIAA_ANAMF ;  Q5PAI0, MIAA_ANAMM ;
DR   Q2GKR7, MIAA_ANAPZ ;  B4UEL1, MIAA_ANASK ;  B9MJT8, MIAA_ANATD ;
DR   Q3MA53, MIAA_ANAVT ;  B7GIA2, MIAA_ANOFW ;  O67162, MIAA_AQUAE ;
DR   A8ER62, MIAA_ARCB4 ;  Q5NXR4, MIAA_AROAE ;  A1R551, MIAA_ARTAT ;
DR   B8HG92, MIAA_ARTCA ;  A0JUY7, MIAA_ARTS2 ;  Q2NJ30, MIAA_AYWBP ;
DR   A8IAX3, MIAA_AZOC5 ;  A1KA92, MIAA_AZOSB ;  C1DLQ1, MIAA_AZOVD ;
DR   A7Z500, MIAA_BACA2 ;  C3P4Y4, MIAA_BACAA ;  C3L886, MIAA_BACAC ;
DR   A0RH88, MIAA_BACAH ;  Q81JG8, MIAA_BACAN ;  B7JIE1, MIAA_BACC0 ;
DR   Q733B9, MIAA_BACC1 ;  B7ISQ9, MIAA_BACC2 ;  C1ENE7, MIAA_BACC3 ;
DR   B7HCI3, MIAA_BACC4 ;  B7HKR9, MIAA_BACC7 ;  A7GR71, MIAA_BACCN ;
DR   B9IUM7, MIAA_BACCQ ;  Q812Y4, MIAA_BACCR ;  Q636W2, MIAA_BACCZ ;
DR   Q9KAC3, MIAA_BACHD ;  Q6HF97, MIAA_BACHK ;  Q65JA9, MIAA_BACLD ;
DR   A8FDI9, MIAA_BACP2 ;  Q5WFY6, MIAA_BACSK ;  O31795, MIAA_BACSU ;
DR   A9VR03, MIAA_BACWK ;  Q6G2T3, MIAA_BARHE ;  Q6FZ96, MIAA_BARQU ;
DR   A9IW77, MIAA_BART1 ;  Q1LSQ3, MIAA_BAUCH ;  Q6MMQ9, MIAA_BDEBA ;
DR   B2IKE2, MIAA_BEII9 ;  B8DT91, MIAA_BIFA0 ;  A1A279, MIAA_BIFAA ;
DR   B3DR79, MIAA_BIFLD ;  Q8CY49, MIAA_BIFLO ;  B7GQG1, MIAA_BIFLS ;
DR   Q7U347, MIAA_BLOFL ;  Q493W0, MIAA_BLOPB ;  Q2KX23, MIAA_BORA1 ;
DR   Q0SM30, MIAA_BORAP ;  Q7U383, MIAA_BORBR ;  O51761, MIAA_BORBU ;
DR   B7J0R6, MIAA_BORBZ ;  B5RN19, MIAA_BORDL ;  Q65ZV3, MIAA_BORGA ;
DR   B2S1G5, MIAA_BORHD ;  Q7U372, MIAA_BORPA ;  A9I7X7, MIAA_BORPD ;
DR   Q7U366, MIAA_BORPE ;  B5RQF8, MIAA_BORRA ;  A1R0P6, MIAA_BORT9 ;
DR   Q89G43, MIAA_BRAJA ;  A5EPC1, MIAA_BRASB ;  A4YZB3, MIAA_BRASO ;
DR   B2S6L5, MIAA_BRUA1 ;  Q2YS31, MIAA_BRUA2 ;  Q57CB7, MIAA_BRUAB ;
DR   A9M648, MIAA_BRUC2 ;  C0RE30, MIAA_BRUMB ;  Q8YI29, MIAA_BRUME ;
DR   A5VRD9, MIAA_BRUO2 ;  B0CHH8, MIAA_BRUSI ;  Q8CY40, MIAA_BRUSU ;
DR   B8D8D3, MIAA_BUCA5 ;  P57632, MIAA_BUCAI ;  B8D890, MIAA_BUCAT ;
DR   P59507, MIAA_BUCBP ;  Q056X7, MIAA_BUCCC ;  B1YTV7, MIAA_BURA4 ;
DR   Q1BYW1, MIAA_BURCA ;  B1JW31, MIAA_BURCC ;  A0K4U0, MIAA_BURCH ;
DR   B4EDH3, MIAA_BURCJ ;  Q0BI05, MIAA_BURCM ;  A9AGA7, MIAA_BURM1 ;
DR   A3MN86, MIAA_BURM7 ;  A2S552, MIAA_BURM9 ;  Q62HE6, MIAA_BURMA ;
DR   A1V0V9, MIAA_BURMS ;  A3NYW4, MIAA_BURP0 ;  Q3JP23, MIAA_BURP1 ;
DR   A3ND55, MIAA_BURP6 ;  B2JGD1, MIAA_BURP8 ;  B2T068, MIAA_BURPP ;
DR   Q63R58, MIAA_BURPS ;  Q39JB5, MIAA_BURS3 ;  Q2SYY3, MIAA_BURTA ;
DR   A4JBT2, MIAA_BURVG ;  Q145C5, MIAA_BURXL ;  A4XL45, MIAA_CALS8 ;
DR   A7ZB92, MIAA_CAMC1 ;  A7GW99, MIAA_CAMC5 ;  A0RMI8, MIAA_CAMFF ;
DR   A7I444, MIAA_CAMHC ;  A8FJX4, MIAA_CAMJ8 ;  A7H1P3, MIAA_CAMJD ;
DR   Q9PIW2, MIAA_CAMJE ;  A1VXP9, MIAA_CAMJJ ;  Q5HX00, MIAA_CAMJR ;
DR   B9KDV7, MIAA_CAMLR ;  Q3ACA8, MIAA_CARHZ ;  B8GXU1, MIAA_CAUCN ;
DR   Q9A6J5, MIAA_CAUCR ;  B0T4U9, MIAA_CAUSK ;  B3PDC2, MIAA_CELJU ;
DR   A9WDJ6, MIAA_CHLAA ;  Q5L530, MIAA_CHLAB ;  B8G9R5, MIAA_CHLAD ;
DR   Q3AQS3, MIAA_CHLCH ;  Q820E1, MIAA_CHLCV ;  Q255V8, MIAA_CHLFF ;
DR   B3EIU4, MIAA_CHLL2 ;  Q9PLF7, MIAA_CHLMU ;  B3QNZ0, MIAA_CHLP8 ;
DR   B3EQM3, MIAA_CHLPB ;  A1BFE5, MIAA_CHLPD ;  Q9Z6Z6, MIAA_CHLPN ;
DR   B9LI82, MIAA_CHLSY ;  B0B8Z2, MIAA_CHLT2 ;  B3QUD7, MIAA_CHLT3 ;
DR   Q3KKS6, MIAA_CHLTA ;  B0BAM1, MIAA_CHLTB ;  Q8KDS2, MIAA_CHLTE ;
DR   O84771, MIAA_CHLTR ;  Q1QY27, MIAA_CHRSD ;  Q7MBE2, MIAA_CHRVO ;
DR   A8AMN0, MIAA_CITK8 ;  A5CSL4, MIAA_CLAM3 ;  B0RGZ2, MIAA_CLAMS ;
DR   Q97I21, MIAA_CLOAB ;  A7FUK8, MIAA_CLOB1 ;  C3KX33, MIAA_CLOB6 ;
DR   A6LWJ0, MIAA_CLOB8 ;  B2V267, MIAA_CLOBA ;  B2TIB7, MIAA_CLOBB ;
DR   A5I2S0, MIAA_CLOBH ;  C1FNT7, MIAA_CLOBJ ;  B1IM66, MIAA_CLOBK ;
DR   A7GE43, MIAA_CLOBL ;  B1KSA1, MIAA_CLOBM ;  Q187T5, MIAA_CLOD6 ;
DR   B9E1Z2, MIAA_CLOK1 ;  A5N8I7, MIAA_CLOK5 ;  A0Q0M8, MIAA_CLONN ;
DR   Q0TRD4, MIAA_CLOP1 ;  Q8XL85, MIAA_CLOPE ;  A9KL08, MIAA_CLOPH ;
DR   Q0STR2, MIAA_CLOPS ;  Q895H4, MIAA_CLOTE ;  A3DDI1, MIAA_CLOTH ;
DR   Q48A23, MIAA_COLP3 ;  B5Y8R8, MIAA_COPPD ;  Q6NGR5, MIAA_CORDI ;
DR   Q8FPE0, MIAA_COREF ;  A4QEV2, MIAA_CORGB ;  Q8NP72, MIAA_CORGL ;
DR   Q4JV82, MIAA_CORJK ;  B1VDE1, MIAA_CORU7 ;  B6J7C0, MIAA_COXB1 ;
DR   B6J017, MIAA_COXB2 ;  A9KE31, MIAA_COXBN ;  A9NCK4, MIAA_COXBR ;
DR   Q820W3, MIAA_COXBU ;  Q0K776, MIAA_CUPNH ;  Q46XK2, MIAA_CUPPJ ;
DR   B3R6B8, MIAA_CUPTR ;  B1X0D2, MIAA_CYAA5 ;  B8HLW6, MIAA_CYAP4 ;
DR   B7KDM5, MIAA_CYAP7 ;  B7K612, MIAA_CYAP8 ;  Q11RE0, MIAA_CYTH3 ;
DR   Q47B80, MIAA_DECAR ;  Q3Z8H3, MIAA_DEHE1 ;  A5FRB5, MIAA_DEHSB ;
DR   Q3ZXC6, MIAA_DEHSC ;  Q1J022, MIAA_DEIGD ;  Q9RTR6, MIAA_DEIRA ;
DR   A9BN87, MIAA_DELAS ;  B8FNN5, MIAA_DESAA ;  C6BXG0, MIAA_DESAD ;
DR   B1I295, MIAA_DESAP ;  B8J3C2, MIAA_DESDA ;  Q310R5, MIAA_DESDG ;
DR   B8FWE4, MIAA_DESHD ;  Q24X66, MIAA_DESHY ;  A9A0U3, MIAA_DESOH ;
DR   Q6ALW6, MIAA_DESPS ;  A4J5Q1, MIAA_DESRM ;  Q72BV1, MIAA_DESVH ;
DR   B8DNS7, MIAA_DESVM ;  A1VDU9, MIAA_DESVV ;  A5EXM7, MIAA_DICNV ;
DR   B5YE43, MIAA_DICT6 ;  B8E281, MIAA_DICTD ;  A8LK35, MIAA_DINSH ;
DR   A7ZV40, MIAA_ECO24 ;  B7UQI0, MIAA_ECO27 ;  B7MKX5, MIAA_ECO45 ;
DR   B7LC30, MIAA_ECO55 ;  Q8XDN3, MIAA_ECO57 ;  B5Z2H7, MIAA_ECO5E ;
DR   B7NTM7, MIAA_ECO7I ;  B7MSY4, MIAA_ECO81 ;  B7M8T1, MIAA_ECO8A ;
DR   C4ZR48, MIAA_ECOBW ;  B1XDS2, MIAA_ECODH ;  A8A7R5, MIAA_ECOHS ;
DR   A1AJ77, MIAA_ECOK1 ;  Q0T9M2, MIAA_ECOL5 ;  Q8CXV3, MIAA_ECOL6 ;
DR   B1IT35, MIAA_ECOLC ;  P16384, MIAA_ECOLI ;  B7NGA5, MIAA_ECOLU ;
DR   B6I275, MIAA_ECOSE ;  B1LQJ1, MIAA_ECOSM ;  Q1R389, MIAA_ECOUT ;
DR   Q3YS11, MIAA_EHRCJ ;  Q2GGN4, MIAA_EHRCR ;  Q5FGV7, MIAA_EHRRG ;
DR   Q5HB92, MIAA_EHRRW ;  B2KDR9, MIAA_ELUMP ;  A4W5R2, MIAA_ENT38 ;
DR   Q820U0, MIAA_ENTFA ;  A7MM88, MIAA_ENTS8 ;  Q6D066, MIAA_ERWCT ;
DR   B2VCX4, MIAA_ERWT9 ;  Q2NAU5, MIAA_ERYLH ;  B7LLV3, MIAA_ESCF3 ;
DR   B1YMH0, MIAA_EXIS2 ;  C4L1B9, MIAA_EXISA ;  A7HJQ9, MIAA_FERNB ;
DR   B0S1C3, MIAA_FINM2 ;  A5FE96, MIAA_FLAJ1 ;  A6H0V8, MIAA_FLAPJ ;
DR   Q0RDX5, MIAA_FRAAA ;  B0TZB0, MIAA_FRAP2 ;  Q2J773, MIAA_FRASC ;
DR   A8L6K0, MIAA_FRASN ;  Q14IJ4, MIAA_FRAT1 ;  A7NBS1, MIAA_FRATF ;
DR   Q2A3T6, MIAA_FRATH ;  B2SG23, MIAA_FRATM ;  A0Q6S4, MIAA_FRATN ;
DR   Q0BM87, MIAA_FRATO ;  Q5NH42, MIAA_FRATT ;  A4IYB1, MIAA_FRATW ;
DR   Q8R5Z6, MIAA_FUSNN ;  Q5L0D9, MIAA_GEOKA ;  Q39TZ3, MIAA_GEOMG ;
DR   Q74BP1, MIAA_GEOSL ;  A4IMI5, MIAA_GEOTN ;  Q7MBC1, MIAA_GLOVI ;
DR   A9GZI5, MIAA_GLUDA ;  Q5FRZ1, MIAA_GLUOX ;  Q0BS22, MIAA_GRABC ;
DR   A0LZ43, MIAA_GRAFK ;  Q7U338, MIAA_HAEDU ;  Q4QPH6, MIAA_HAEI8 ;
DR   A5UB70, MIAA_HAEIE ;  P44495, MIAA_HAEIN ;  B8F662, MIAA_HAEPS ;
DR   Q0I462, MIAA_HAES1 ;  B0UUU6, MIAA_HAES2 ;  A1WUT7, MIAA_HALHL ;
DR   B8CX96, MIAA_HALOH ;  Q17ZN6, MIAA_HELAH ;  Q7U323, MIAA_HELHP ;
DR   B0TB07, MIAA_HELMI ;  B6JNQ7, MIAA_HELP2 ;  B5Z937, MIAA_HELPG ;
DR   Q1CRL4, MIAA_HELPH ;  Q9ZJJ7, MIAA_HELPJ ;  B2UVF6, MIAA_HELPS ;
DR   O25961, MIAA_HELPY ;  A9AY15, MIAA_HERA2 ;  A4G288, MIAA_HERAR ;
DR   B4U6P0, MIAA_HYDS0 ;  Q0C511, MIAA_HYPNA ;  Q5QWA0, MIAA_IDILO ;
DR   A6SV54, MIAA_JANMA ;  Q28PI4, MIAA_JANSC ;  A6W849, MIAA_KINRD ;
DR   B5Y333, MIAA_KLEP3 ;  A6TH86, MIAA_KLEP7 ;  B2GKG9, MIAA_KOCRD ;
DR   C5CD61, MIAA_KOSOT ;  Q5FJ02, MIAA_LACAC ;  Q03RP7, MIAA_LACBA ;
DR   Q038E3, MIAA_LACC3 ;  B3WF00, MIAA_LACCB ;  Q1G9D6, MIAA_LACDA ;
DR   Q049I6, MIAA_LACDB ;  B2GD80, MIAA_LACF3 ;  Q041Y0, MIAA_LACGA ;
DR   A8YWA5, MIAA_LACH4 ;  Q74IF3, MIAA_LACJO ;  Q9CHU2, MIAA_LACLA ;
DR   A2RIU4, MIAA_LACLM ;  Q031A8, MIAA_LACLS ;  Q88WP5, MIAA_LACPL ;
DR   A5VKT6, MIAA_LACRD ;  B2G870, MIAA_LACRJ ;  Q1WUH1, MIAA_LACS1 ;
DR   Q38W03, MIAA_LACSS ;  Q1MRN9, MIAA_LAWIP ;  Q5X1J2, MIAA_LEGPA ;
DR   A5IAM8, MIAA_LEGPC ;  Q5ZS23, MIAA_LEGPH ;  Q5WTA1, MIAA_LEGPL ;
DR   Q6AE04, MIAA_LEIXX ;  B0SBH8, MIAA_LEPBA ;  Q04S66, MIAA_LEPBJ ;
DR   Q04ZZ3, MIAA_LEPBL ;  B0SJ27, MIAA_LEPBP ;  B1Y5G6, MIAA_LEPCP ;
DR   Q72Q66, MIAA_LEPIC ;  Q8CXT5, MIAA_LEPIN ;  B1MXL9, MIAA_LEUCK ;
DR   Q03VI2, MIAA_LEUMM ;  Q92C59, MIAA_LISIN ;  C1L2K1, MIAA_LISMC ;
DR   Q720C8, MIAA_LISMF ;  B8DG34, MIAA_LISMH ;  Q8Y7I3, MIAA_LISMO ;
DR   A0AI95, MIAA_LISW6 ;  B1HRH3, MIAA_LYSSC ;  B9EBJ1, MIAA_MACCJ ;
DR   Q2W1G5, MIAA_MAGSA ;  A0L4B0, MIAA_MAGSM ;  Q65SD6, MIAA_MANSM ;
DR   A1U4C6, MIAA_MARAV ;  Q0AN24, MIAA_MARMM ;  A6VYL7, MIAA_MARMS ;
DR   Q11HI8, MIAA_MESSB ;  B7KQF6, MIAA_METC4 ;  Q607R4, MIAA_METCA ;
DR   A9W640, MIAA_METEP ;  Q1H1I4, MIAA_METFK ;  B3DXP7, MIAA_METI4 ;
DR   B8IEX6, MIAA_METNO ;  B1ZDL3, MIAA_METPB ;  A2SHF3, MIAA_METPP ;
DR   B1M537, MIAA_METRJ ;  B0UPN1, MIAA_METS4 ;  B8EQB8, MIAA_METSB ;
DR   B0JN42, MIAA_MICAN ;  Q2RJG0, MIAA_MOOTA ;  A0QIQ9, MIAA_MYCA1 ;
DR   B1MD01, MIAA_MYCA9 ;  P65353, MIAA_MYCBO ;  A1KM65, MIAA_MYCBP ;
DR   C1AFI6, MIAA_MYCBT ;  Q7NBU2, MIAA_MYCGA ;  A4TCN4, MIAA_MYCGI ;
DR   B8ZQU0, MIAA_MYCLB ;  P46811, MIAA_MYCLE ;  Q73W20, MIAA_MYCPA ;
DR   Q8CXQ5, MIAA_MYCPE ;  A0QVX9, MIAA_MYCS2 ;  A3PYF8, MIAA_MYCSJ ;
DR   A1UEZ8, MIAA_MYCSK ;  Q1BA14, MIAA_MYCSS ;  A5U679, MIAA_MYCTA ;
DR   P65352, MIAA_MYCTU ;  A1T7U7, MIAA_MYCVP ;  Q1D607, MIAA_MYXXD ;
DR   B2A3X9, MIAA_NATTJ ;  B9L615, MIAA_NAUPA ;  Q5F852, MIAA_NEIG1 ;
DR   B4RL47, MIAA_NEIG2 ;  A9M4D3, MIAA_NEIM0 ;  Q9JUU5, MIAA_NEIMA ;
DR   Q9JZR0, MIAA_NEIMB ;  A1KTK4, MIAA_NEIMF ;  Q2GDJ5, MIAA_NEOSM ;
DR   Q0AJ07, MIAA_NITEC ;  Q820J6, MIAA_NITEU ;  Q1QJU5, MIAA_NITHX ;
DR   Q2YCX0, MIAA_NITMU ;  Q3J802, MIAA_NITOC ;  A6Q1Q8, MIAA_NITSB ;
DR   Q3SQ43, MIAA_NITWN ;  Q5YT12, MIAA_NOCFA ;  A1SNF6, MIAA_NOCSJ ;
DR   B2IY45, MIAA_NOSP7 ;  Q8YLN2, MIAA_NOSS1 ;  Q2G626, MIAA_NOVAD ;
DR   Q8CXG5, MIAA_OCEIH ;  A6WZW3, MIAA_OCHA4 ;  Q04FB0, MIAA_OENOB ;
DR   B6JB74, MIAA_OLICO ;  Q6YQU8, MIAA_ONYPE ;  B1ZT51, MIAA_OPITP ;
DR   A5CDI3, MIAA_ORITB ;  B3CUN6, MIAA_ORITI ;  A1B964, MIAA_PARDP ;
DR   A7HVY9, MIAA_PARL1 ;  Q6MBT2, MIAA_PARUW ;  Q9CMC7, MIAA_PASMU ;
DR   C6DFJ8, MIAA_PECCP ;  Q03G75, MIAA_PEDPA ;  Q3B3N9, MIAA_PELLD ;
DR   B4SGR0, MIAA_PELPB ;  A5D2K7, MIAA_PELTS ;  Q4FPN1, MIAA_PELUB ;
DR   A9BHW9, MIAA_PETMO ;  B4RGS2, MIAA_PHEZH ;  Q7MAX8, MIAA_PHOLL ;
DR   Q6LM29, MIAA_PHOPR ;  B1VAJ9, MIAA_PHYAS ;  B3R0E8, MIAA_PHYMT ;
DR   A1VLE3, MIAA_POLNA ;  B1XRT3, MIAA_POLNS ;  Q128B6, MIAA_POLSJ ;
DR   A4SZQ9, MIAA_POLSQ ;  Q6A8Z5, MIAA_PROAC ;  A3PFC4, MIAA_PROM0 ;
DR   A2C585, MIAA_PROM1 ;  A8G7E1, MIAA_PROM2 ;  A2C601, MIAA_PROM3 ;
DR   A9BD80, MIAA_PROM4 ;  A2BZ20, MIAA_PROM5 ;  Q318A6, MIAA_PROM9 ;
DR   Q7TV89, MIAA_PROMA ;  B4F265, MIAA_PROMH ;  Q7TV75, MIAA_PROMM ;
DR   Q7TU25, MIAA_PROMP ;  A2BTL7, MIAA_PROMS ;  Q46IH4, MIAA_PROMT ;
DR   A4SE82, MIAA_PROVI ;  Q48P03, MIAA_PSE14 ;  Q15NR1, MIAA_PSEA6 ;
DR   A6VD58, MIAA_PSEA7 ;  B7V208, MIAA_PSEA8 ;  Q02F73, MIAA_PSEAB ;
DR   Q9HUL9, MIAA_PSEAE ;  Q1I448, MIAA_PSEE4 ;  Q4KJ74, MIAA_PSEF5 ;
DR   C3KDW2, MIAA_PSEFS ;  Q3IDT9, MIAA_PSEHT ;  A4XPY6, MIAA_PSEMY ;
DR   A5W9T1, MIAA_PSEP1 ;  Q3KIZ0, MIAA_PSEPF ;  B0KKZ6, MIAA_PSEPG ;
DR   Q88DD2, MIAA_PSEPK ;  O30762, MIAA_PSEPU ;  B1JAD5, MIAA_PSEPW ;
DR   Q87VJ3, MIAA_PSESM ;  Q4ZYY1, MIAA_PSEU2 ;  A4VQP1, MIAA_PSEU5 ;
DR   Q4FT85, MIAA_PSYA2 ;  Q1QAN0, MIAA_PSYCK ;  A1SZL1, MIAA_PSYIN ;
DR   A5WDN1, MIAA_PSYWF ;  Q1LJ94, MIAA_RALME ;  B2UBL0, MIAA_RALPJ ;
DR   Q8XWB0, MIAA_RALSO ;  A9WQ48, MIAA_RENSM ;  B3PTP8, MIAA_RHIE6 ;
DR   Q2K6H4, MIAA_RHIEC ;  Q1ME89, MIAA_RHIL3 ;  Q98KJ4, MIAA_RHILO ;
DR   B5ZVU9, MIAA_RHILW ;  Q92NR2, MIAA_RHIME ;  P0A3Q6, MIAA_RHIRD ;
DR   Q7TU09, MIAA_RHOBA ;  B6ITS0, MIAA_RHOCS ;  Q21Y86, MIAA_RHOFD ;
DR   Q2IUR8, MIAA_RHOP2 ;  Q07PK4, MIAA_RHOP5 ;  Q6N874, MIAA_RHOPA ;
DR   Q211Y8, MIAA_RHOPB ;  Q139A7, MIAA_RHOPS ;  B3QCV7, MIAA_RHOPT ;
DR   Q2RX74, MIAA_RHORT ;  A3PJF5, MIAA_RHOS1 ;  Q3J2X6, MIAA_RHOS4 ;
DR   A4WUI0, MIAA_RHOS5 ;  B9KRT8, MIAA_RHOSK ;  Q0S1N9, MIAA_RHOSR ;
DR   A8GNL2, MIAA_RICAH ;  A8GWV8, MIAA_RICB8 ;  Q1RIF4, MIAA_RICBR ;
DR   A8EYU8, MIAA_RICCK ;  Q92HW4, MIAA_RICCN ;  Q4ULK8, MIAA_RICFE ;
DR   A8F1N7, MIAA_RICM5 ;  Q9ZD37, MIAA_RICPR ;  B0BXQ1, MIAA_RICRO ;
DR   A8GS87, MIAA_RICRS ;  Q68WM5, MIAA_RICTY ;  A7NRZ0, MIAA_ROSCS ;
DR   Q166F7, MIAA_ROSDO ;  A5UYJ2, MIAA_ROSS1 ;  Q1AW38, MIAA_RUBXD ;
DR   A1AX35, MIAA_RUTMC ;  Q21HA1, MIAA_SACD2 ;  A4FAJ5, MIAA_SACEN ;
DR   B5F386, MIAA_SALA4 ;  A8M7W9, MIAA_SALAI ;  A9MFP1, MIAA_SALAR ;
DR   Q57GM0, MIAA_SALCH ;  B5FRM7, MIAA_SALDC ;  B5R0N8, MIAA_SALEP ;
DR   B5R9B8, MIAA_SALG2 ;  B4TFA5, MIAA_SALHS ;  B4T2R6, MIAA_SALNS ;
DR   Q5PL48, MIAA_SALPA ;  A9N4Y5, MIAA_SALPB ;  C0Q6C8, MIAA_SALPC ;
DR   B5BKI0, MIAA_SALPK ;  Q2S2F9, MIAA_SALRD ;  B4TSF1, MIAA_SALSV ;
DR   Q8Z186, MIAA_SALTI ;  A4X4W1, MIAA_SALTO ;  P37724, MIAA_SALTY ;
DR   A8G8U8, MIAA_SERP5 ;  A1SA22, MIAA_SHEAM ;  B8ECA4, MIAA_SHEB2 ;
DR   A3D023, MIAA_SHEB5 ;  A6WSV3, MIAA_SHEB8 ;  A9L3W0, MIAA_SHEB9 ;
DR   Q12J94, MIAA_SHEDO ;  Q07XW6, MIAA_SHEFN ;  B0TU65, MIAA_SHEHH ;
DR   A3QAD9, MIAA_SHELP ;  Q8CX50, MIAA_SHEON ;  A8H8G7, MIAA_SHEPA ;
DR   A4YAL0, MIAA_SHEPC ;  B8CIX4, MIAA_SHEPW ;  A0KSR6, MIAA_SHESA ;
DR   Q0HMP0, MIAA_SHESM ;  Q0HR41, MIAA_SHESR ;  A1RFR6, MIAA_SHESW ;
DR   B1KHU9, MIAA_SHEWM ;  B2TY46, MIAA_SHIB3 ;  Q31TA1, MIAA_SHIBS ;
DR   Q328F0, MIAA_SHIDS ;  Q0SXB1, MIAA_SHIF8 ;  P59197, MIAA_SHIFL ;
DR   Q3YUH2, MIAA_SHISS ;  Q5LSV5, MIAA_SILPO ;  Q1GGR8, MIAA_SILST ;
DR   A6UB14, MIAA_SINMW ;  Q2NW64, MIAA_SODGM ;  Q029I5, MIAA_SOLUE ;
DR   A9G9R0, MIAA_SORC5 ;  Q1GT40, MIAA_SPHAL ;  A5V3W0, MIAA_SPHWW ;
DR   A7X1U8, MIAA_STAA1 ;  A6U1C1, MIAA_STAA2 ;  Q2FHD6, MIAA_STAA3 ;
DR   Q2FYZ2, MIAA_STAA8 ;  A5ISI5, MIAA_STAA9 ;  Q2YXR3, MIAA_STAAB ;
DR   Q5HGC9, MIAA_STAAC ;  A6QGK1, MIAA_STAAE ;  P65354, MIAA_STAAM ;
DR   P65355, MIAA_STAAN ;  Q6GHD2, MIAA_STAAR ;  Q6G9R0, MIAA_STAAS ;
DR   A8Z1X3, MIAA_STAAT ;  P65356, MIAA_STAAW ;  B9DPA1, MIAA_STACT ;
DR   Q5HPN8, MIAA_STAEQ ;  Q8CQL3, MIAA_STAES ;  Q4L610, MIAA_STAHJ ;
DR   Q49X96, MIAA_STAS1 ;  Q3K0P1, MIAA_STRA1 ;  Q8E4V8, MIAA_STRA3 ;
DR   Q8CX09, MIAA_STRA5 ;  Q82KC8, MIAA_STRAW ;  O69967, MIAA_STRCO ;
DR   C0MAN2, MIAA_STRE4 ;  B4U3M4, MIAA_STREM ;  A8AWX1, MIAA_STRGC ;
DR   B1VXU2, MIAA_STRGG ;  B4SRA4, MIAA_STRM5 ;  B2FL25, MIAA_STRMK ;
DR   Q8DT87, MIAA_STRMU ;  Q9A059, MIAA_STRP1 ;  Q04LL6, MIAA_STRP2 ;
DR   P0DC32, MIAA_STRP3 ;  B5E2R3, MIAA_STRP4 ;  Q5XCI0, MIAA_STRP6 ;
DR   P65358, MIAA_STRP8 ;  Q1JC62, MIAA_STRPB ;  Q1JM45, MIAA_STRPC ;
DR   Q1JH90, MIAA_STRPD ;  Q1J708, MIAA_STRPF ;  A2REY5, MIAA_STRPG ;
DR   B1IAK9, MIAA_STRPI ;  B8ZMQ3, MIAA_STRPJ ;  Q48TZ1, MIAA_STRPM ;
DR   Q97RW5, MIAA_STRPN ;  P0DC33, MIAA_STRPQ ;  B2IMY5, MIAA_STRPS ;
DR   B5XL33, MIAA_STRPZ ;  Q8CWS7, MIAA_STRR6 ;  A4W2A2, MIAA_STRS2 ;
DR   C0MDJ6, MIAA_STRS7 ;  A3CNS2, MIAA_STRSV ;  A4VVZ3, MIAA_STRSY ;
DR   Q5LZH6, MIAA_STRT1 ;  Q5M430, MIAA_STRT2 ;  Q03KD9, MIAA_STRTD ;
DR   B9DUP8, MIAA_STRU0 ;  C1CJD7, MIAA_STRZP ;  C1CQE9, MIAA_STRZT ;
DR   Q30PJ5, MIAA_SULDN ;  A6QCE8, MIAA_SULNB ;  B2VAE4, MIAA_SULSY ;
DR   Q67NL1, MIAA_SYMTH ;  Q8GIT6, MIAA_SYNE7 ;  A0LJK3, MIAA_SYNFM ;
DR   Q2JY05, MIAA_SYNJA ;  Q2JK09, MIAA_SYNJB ;  B1XKE8, MIAA_SYNP2 ;
DR   Q5N1L4, MIAA_SYNP6 ;  A5GI07, MIAA_SYNPW ;  Q7TTX9, MIAA_SYNPX ;
DR   A5GQ35, MIAA_SYNR3 ;  Q0IDZ4, MIAA_SYNS3 ;  Q3B0M1, MIAA_SYNS9 ;
DR   Q3ANG7, MIAA_SYNSC ;  Q0AYB0, MIAA_SYNWW ;  P74040, MIAA_SYNY3 ;
DR   B7IDS3, MIAA_THEAB ;  Q8CWM5, MIAA_THEEB ;  Q47RR4, MIAA_THEFY ;
DR   A8F5B3, MIAA_THELT ;  A6LMU4, MIAA_THEM4 ;  Q9WYZ5, MIAA_THEMA ;
DR   B9KBC5, MIAA_THENN ;  A5IJP9, MIAA_THEP1 ;  B0K9L7, MIAA_THEP3 ;
DR   B0K1A4, MIAA_THEPX ;  B9L505, MIAA_THERP ;  B1L8X0, MIAA_THESQ ;
DR   Q72L59, MIAA_THET2 ;  Q5SKS1, MIAA_THET8 ;  Q8R5S5, MIAA_THETN ;
DR   B5YK93, MIAA_THEYD ;  Q31GP3, MIAA_THICR ;  Q3SIR0, MIAA_THIDA ;
DR   B8GNC6, MIAA_THISH ;  C4L9N0, MIAA_TOLAT ;  O83644, MIAA_TREPA ;
DR   B2S3M6, MIAA_TREPS ;  Q10XN7, MIAA_TRIEI ;  Q820Y7, MIAA_TROW8 ;
DR   Q820X9, MIAA_TROWT ;  B1H0C6, MIAA_UNCTG ;  A1WQM5, MIAA_VEREI ;
DR   A5CW57, MIAA_VESOH ;  A5F3L6, MIAA_VIBC3 ;  Q9KV12, MIAA_VIBCH ;
DR   C3LR78, MIAA_VIBCM ;  Q5E2C7, MIAA_VIBF1 ;  B5FBR5, MIAA_VIBFM ;
DR   A7MX77, MIAA_VIBHB ;  Q87L06, MIAA_VIBPA ;  B7VI54, MIAA_VIBSL ;
DR   Q8CWK9, MIAA_VIBVU ;  Q7M7I8, MIAA_VIBVY ;  Q8D318, MIAA_WIGBR ;
DR   Q73GV7, MIAA_WOLPM ;  B3CNB0, MIAA_WOLPP ;  Q7M800, MIAA_WOLSU ;
DR   Q5GS00, MIAA_WOLTR ;  C0R3P3, MIAA_WOLWR ;  Q8PLQ5, MIAA_XANAC ;
DR   Q3BUR5, MIAA_XANC5 ;  Q4UTQ7, MIAA_XANC8 ;  B0RTZ0, MIAA_XANCB ;
DR   Q8P9X8, MIAA_XANCP ;  Q2P1M3, MIAA_XANOM ;  B2SUC1, MIAA_XANOP ;
DR   Q5GYM0, MIAA_XANOR ;  A7IFW1, MIAA_XANP2 ;  B2I692, MIAA_XYLF2 ;
DR   Q9PH56, MIAA_XYLFA ;  B0U1E8, MIAA_XYLFM ;  Q87F70, MIAA_XYLFT ;
DR   A1JIR4, MIAA_YERE8 ;  A7FMY0, MIAA_YERP3 ;  Q1C0Z9, MIAA_YERPA ;
DR   B2K203, MIAA_YERPB ;  Q8ZIW3, MIAA_YERPE ;  A9QYN2, MIAA_YERPG ;
DR   Q1CEF4, MIAA_YERPN ;  A4TRP0, MIAA_YERPP ;  Q66FB6, MIAA_YERPS ;
DR   B1JMP0, MIAA_YERPY ;  Q9X5G1, MIAA_ZYMMO ;  Q9H3H1, MOD5_HUMAN ;
DR   Q80UN9, MOD5_MOUSE ;  Q9UT75, MOD5_SCHPO ;  P07884, MOD5_YEAST ;
//
ID   2.5.1.76
DE   Cysteate synthase.
CA   O-phospho-L-serine + sulfite = L-cysteate + phosphate.
CF   Pyridoxal 5'-phosphate.
CC   -!- It is highly specific for O-phospho-L-serine and sulfite.
CC   -!- The reaction proceeds through a dehydroalanine (2-aminoacrylic acid)
CC       intermediate.
CC   -!- The enzyme from Methanosarcina acetivorans is evolutionarily related
CC       to EC 4.2.3.1, but the reaction is more similar to that of
CC       EC 2.5.1.65.
DR   Q8TKU7, CYAS_METAC ;  A7IA69, CYAS_METB6 ;  Q465N2, CYAS_METBF ;
DR   Q12W15, CYAS_METBU ;  Q2FSC3, CYAS_METHJ ;  A2SQS1, CYAS_METLZ ;
DR   Q8Q0K3, CYAS_METMA ;  A3CRP6, CYAS_METMJ ;  B8GFW4, CYAS_METPE ;
DR   D1Z042, CYAS_METPS ;  A0B6Z6, CYAS_METTP ;  Q0W896, CYAS_UNCMA ;
//
ID   2.5.1.77
DE   7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase.
CA   5-amino-6-(D-ribitylamino)uracil + 3-(4-hydroxyphenyl)pyruvate +
CA   2 S-adenosyl-L-methionine + H(2)O = 7,8-didemethyl-8-hydroxy-5-
CA   deazariboflavin + 2 L-methionine + 2 5'-deoxyadenosine + oxalate + NH(3).
CF   Iron-sulfur.
CC   -!- Binds a 4Fe-4S cluster.
CC   -!- The cluster is coordinated by 3 cysteines and an exchangeable SAM
CC       molecule.
CC   -!- The first stage of catalysis is reduction of the 2 AdoMet to produce
CC       2 methionine and 2 5'-deoxyadenosin-5-yl radicals that extract a
CC       hydrogen from each of the substrates permitting the condensation of
CC       the two.
CC   -!- The overall reaction catalyzed is the transfer of the hydroxybenzyl
CC       group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-
CC       ribitylaminopyrimidine-2,4(1H,3H)-dione to form 7,8-didemethyl-8-
CC       hydroxy-5-deazariboflavin (FO).
CC   -!- 7,8-didemethyl-8-hydroxy-5-deazariboflavin is the chromophore of the
CC       hydride carrier coenzyme F420.
DR   Q3MCR5, COFG_ANAVT ;  O29461, COFG_ARCFU ;  Q7NIT2, COFG_GLOVI ;
DR   Q5UXN0, COFG_HALMA ;  B0R6P8, COFG_HALS3 ;  Q9HNU9, COFG_HALSA ;
DR   A6UVH0, COFG_META3 ;  Q8TQP9, COFG_METAC ;  A7IAF4, COFG_METB6 ;
DR   Q466A4, COFG_METBF ;  Q12WF6, COFG_METBU ;  Q57888, COFG_METJA ;
DR   Q8TWY3, COFG_METKA ;  A4FXR1, COFG_METM5 ;  A9AB67, COFG_METM6 ;
DR   A6VFG8, COFG_METM7 ;  Q8PU55, COFG_METMA ;  A3CWL4, COFG_METMJ ;
DR   Q6LYV9, COFG_METMP ;  B8GGS3, COFG_METPE ;  A5UM12, COFG_METS3 ;
DR   O27266, COFG_METTH ;  A0B5P5, COFG_METTP ;  A6UN87, COFG_METVS ;
DR   Q8YR77, COFG_NOSS1 ;  Q31PU7, COFG_SYNE7 ;  Q5N4D1, COFG_SYNP6 ;
DR   P73191, COFG_SYNY3 ;  Q8DIR6, COFG_THEEB ;  Q11A09, COFG_TRIEI ;
DR   Q8TQQ0, COFH1_METAC;  Q466A3, COFH1_METBF;  Q8PU54, COFH1_METMA;
DR   Q6M161, COFH1_METMP;  Q8TQQ1, COFH2_METAC;  Q466A2, COFH2_METBF;
DR   Q8PU53, COFH2_METMA;  Q6M160, COFH2_METMP;  Q3MF37, COFH_ANAVT ;
DR   O29460, COFH_ARCFU ;  B8HP19, COFH_CYAP4 ;  Q7NMI9, COFH_GLOVI ;
DR   Q5UXN1, COFH_HALMA ;  Q9HNU8, COFH_HALSA ;  A6UV11, COFH_META3 ;
DR   Q12WF5, COFH_METBU ;  Q2FSC7, COFH_METHJ ;  Q58826, COFH_METJA ;
DR   Q8TWY4, COFH_METKA ;  A4G0D4, COFH_METM5 ;  A9A8N5, COFH_METM6 ;
DR   A6VI43, COFH_METM7 ;  A3CRI3, COFH_METMJ ;  B8GI94, COFH_METPE ;
DR   O26911, COFH_METTH ;  A6UR49, COFH_METVS ;  B0JTF9, COFH_MICAN ;
DR   B2IW30, COFH_NOSP7 ;  Q8YPR3, COFH_NOSS1 ;  Q31QF1, COFH_SYNE7 ;
DR   Q5N3T7, COFH_SYNP6 ;  P72811, COFH_SYNY3 ;  Q8DII8, COFH_THEEB ;
DR   Q113H3, COFH_TRIEI ;  Q0W6V4, COFH_UNCMA ;  Q7U0G9, FBIC_MYCBO ;
DR   Q9CBX6, FBIC_MYCLE ;  Q73WP9, FBIC_MYCPA ;  O50429, FBIC_MYCTU ;
DR   Q5YQD7, FBIC_NOCFA ;  Q82GV2, FBIC_STRAW ;  Q9KZZ7, FBIC_STRCO ;
//
ID   2.5.1.78
DE   6,7-dimethyl-8-ribityllumazine synthase.
AN   Lumazine synthase.
CA   1-deoxy-L-glycero-tetrulose 4-phosphate + 5-amino-6-
CA   (D-ribitylamino)uracil = 6,7-dimethyl-8-(D-ribityl)lumazine + 2 H(2)O +
CA   phosphate.
CC   -!- Involved in riboflavin biosynthesis.
//
ID   2.5.1.79
DE   Thermospermine synthase.
CA   S-adenosylmethioninamine + spermidine = S-methyl-5'-thioadenosine +
CA   thermospermine + H(+).
CC   -!- This enzyme is required for correct xylem specification through
CC       regulation of the lifetime of the xylem elements.
PR   PROSITE; PDOC01033;
DR   Q9S7X6, ACL5_ARATH ;
//
ID   2.5.1.80
DE   7-dimethylallyltryptophan synthase.
AN   7-DMATS.
CA   Dimethylallyl diphosphate + L-tryptophan = diphosphate + 7-(3-methylbut-
CA   2-enyl)-L-tryptophan.
CC   -!- This enzyme is more flexible toward the aromatic substrate than
CC       EC 2.5.1.34, but similar to that enzyme, accepts only dimethylallyl
CC       diphosphate as the prenyl donor.
//
ID   2.5.1.81
DE   Geranylfarnesyl diphosphate synthase.
AN   FGPP synthase.
CA   Geranylgeranyl diphosphate + isopentenyl diphosphate = (2E,6E,10E,14E)-
CA   geranylfarnesyl diphosphate + diphosphate.
CC   -!- The enzyme from Methanosarcina mazei is involved in biosynthesis of
CC       the polyprenyl side-chain of methanophenazine, an electron carrier
CC       utilized for methanogenesis.
CC   -!- It prefers geranylgeranyl diphosphate and farnesyl diphosphate as
CC       allylic substrate.
CC   -!- The enzyme from Aeropyrum pernix prefers farnesyl diphosphate as
CC       allylic substrate.
CC   -!- The enzyme is involved in the biosynthesis of C(25)-C(25) membrane
CC       lipids.
CC   -!- Formerly EC 2.5.1.n2.
//
ID   2.5.1.82
DE   Hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific).
AN   (All-trans)-hexaprenyl-diphosphate synthase.
CA   Geranylgeranyl diphosphate + 2 isopentenyl diphosphate = 2 diphosphate +
CA   all-trans-hexaprenyl diphosphate.
CF   Magnesium.
CC   -!- The enzyme prefers geranylgeranyl diphosphate to farnesyl diphosphate
CC       as an allylic substrate and does not show activity for geranyl
CC       diphosphate and dimethylallyl diphosphate.
CC   -!- Formerly EC 2.5.1.33.
//
ID   2.5.1.83
DE   Hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific).
AN   Hexaprenyl diphosphate synthase.
AN   Hexaprenyl pyrophosphate synthetase.
AN   HexPS.
CA   (2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate = 3 diphosphate
CA   + all-trans-hexaprenyl diphosphate.
CC   -!- The enzyme prefers farnesyl diphosphate to geranylgeranyl diphosphate
CC       as an allylic substrate and does not show activity for geranyl
CC       diphosphate and dimethylallyl diphosphate.
CC   -!- Formerly EC 2.5.1.33.
//
ID   2.5.1.84
DE   All-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific).
AN   Nonaprenyl diphosphate synthase.
AN   Solanesyl-diphosphate synthase.
CA   Geranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-
CA   trans-nonaprenyl diphosphate.
CC   -!- (2E,6E)-Farnesyl diphosphate and geranylgeranyl diphosphate are less
CC       effective as substrates than geranyl diphosphate.
CC   -!- The enzyme is involved in the synthesis of the side chain of
CC       menaquinone-9.
CC   -!- In Oryza sativa the enzyme SPS2 is involved in providing solanesyl
CC       diphosphate for plastoquinone-9 formation.
CC   -!- Formerly EC 2.5.1.11.
//
ID   2.5.1.85
DE   All-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate
DE   specific).
AN   Nonaprenyl diphosphate synthase.
AN   Solanesyl diphosphate synthase.
CA   Geranylgeranyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate +
CA   all-trans-nonaprenyl diphosphate.
CC   -!- Geranylgeranyl diphosphate is preferred over farnesyl diphosphate as
CC       allylic substrate.
CC   -!- The plant Arabidopsis thaliana has two different enzymes that
CC       catalyze this reaction.
CC   -!- SPS1 contributes to the biosynthesis of the ubiquinone side-chain
CC       while SPS2 supplies the precursor of the plastoquinone side-chains.
CC   -!- Formerly 2.5.1.11.
//
ID   2.5.1.86
DE   Trans,poly-cis-decaprenyl diphosphate synthase.
AN   (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate synthase.
CA   (2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate
CA   + (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate.
CC   -!- The enzyme is involved in the biosynthesis of decaprenyl phosphate,
CC       which plays a central role in the biosynthesis of essential
CC       mycobacterial cell wall components, such as the mycolyl-
CC       arabinogalactan-peptidoglycan complex and lipoarabinomannan.
//
ID   2.5.1.87
DE   Di-trans,poly-cis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl
DE   diphosphate specific).
AN   Dehydrodolichyl diphosphate synthase 1.
AN   Rer2p Z-prenyltransferase.
CA   (2E,6E)-farnesyl diphosphate + n isopentenyl diphosphate = n diphosphate
CA   + di-trans,poly-cis-polyprenyl diphosphate (n = 10-55).
CC   -!- The enzyme is involved in biosynthesis of dolichol (a long-chain
CC       polyprenol) with a saturated alpha-isoprene unit, which serves as a
CC       glycosyl carrier in protein glycosylation.
CC   -!- The yeast Saccharomyces cerevisiae has two different enzymes that
CC       catalyze this reaction.
CC   -!- Rer2p synthesizes a well-defined family of polyprenols of 13-18
CC       isoprene residues with dominating C(80) (16 isoprene residues)
CC       extending to C(120), while Srt1p synthesizes mainly polyprenol with
CC       22 isoprene subunits.
CC   -!- Largest Srt1p products reach C(290).
CC   -!- The enzyme from Arabidopsis thaliana catalyzes the formation of
CC       polyprenyl diphosphates with predominant carbon number C(120).
//
ID   2.5.1.88
DE   Trans,poly-cis-polyprenyl diphosphate synthase ((2Z,6E)-farnesyl
DE   diphosphate specific).
CA   (2Z,6E)-farnesyl diphosphate + n isopentenyl diphosphate = n diphosphate
CA   + trans,poly-cis-polyprenyl diphosphate (n = 9-11).
CC   -!- Highest activity with (2Z,6E)-farnesyl diphosphate as allylic
CC       substrate.
CC   -!- Broad product specificity with the major product being dodecaprenyl
CC       diphosphate.
CC   -!- Synthesizes even C(70) prenyl diphosphate as the maximum chain-length
CC       product.
//
ID   2.5.1.89
DE   Tri-trans,poly-cis-undecaprenyl-diphosphate synthase (geranylgeranyl-
DE   diphosphate specific).
CA   Geranylgeranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate +
CA   tri-trans,hepta-cis-undecaprenyl diphosphate.
CC   -!- This enzyme is involved in the biosynthesis of the glycosyl carrier
CC       lipid in some archaebacteria.
CC   -!- Unlike EC 2.5.1.31, its counterpart in most bacteria, it prefers
CC       geranylgeranyl diphosphate to farnesyl diphosphate as the allylic
CC       substrate, resulting in production of a tri-trans,poly-cis variant of
CC       undecaprenyl diphosphate.
//
ID   2.5.1.90
DE   All-trans-octaprenyl-diphosphate synthase.
AN   Octaprenyl pyrophosphate synthetase.
AN   Terpenyl pyrophosphate synthetase.
AN   Trans-heptaprenyltranstransferase.
AN   Trans-prenyltransferase.
CA   (2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate
CA   + all-trans-octaprenyl diphosphate.
CC   -!- This enzyme catalyzes the condensation reactions resulting in the
CC       formation of all-trans-octaprenyl diphosphate, the isoprenoid side
CC       chain of ubiquinone-8 and menaquinone-8.
CC   -!- The enzyme adds five isopentenyl diphosphate molecules sequentially
CC       to farnesyl diphosphate with trans stereochemistry.
DR   P0AD57, ISPB_ECOLI ;  P44916, ISPB_HAEIN ;  P0AD58, ISPB_SHIFL ;
//
ID   2.5.1.91
DE   All-trans-decaprenyl-diphosphate synthase.
AN   Decaprenyl pyrophosphate synthetase.
AN   Decaprenyl-diphosphate synthase.
AN   Polyprenylpyrophosphate synthetase.
AN   Terpenoidallyltransferase.
AN   Terpenyl pyrophosphate synthetase.
AN   Trans-prenyltransferase.
CA   (2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate
CA   + all-trans-decaprenyl diphosphate.
CC   -!- This enzyme catalyzes the condensation reactions resulting in the
CC       formation of all-trans-decaprenyl diphosphate, the isoprenoid side
CC       chain of ubiquinone-10 and menaquinone-10.
CC   -!- The enzyme adds seven isopentenyl diphosphate molecules sequentially
CC       to farnesyl diphosphate with trans stereochemistry.
DR   Q86YH6, DLP1_HUMAN ;  Q33DR3, DLP1_MOUSE ;  Q5U2R1, DLP1_RAT   ;
DR   O13851, DLP1_SCHPO ;  Q54VJ9, DPS1_DICDI ;  Q5T2R2, DPS1_HUMAN ;
DR   Q33DR2, DPS1_MOUSE ;  O43091, DPS1_SCHPO ;
//
ID   2.5.1.92
DE   (2Z,6Z)-farnesyl diphosphate synthase.
AN   Cis,cis-farnesyl diphosphate synthase.
AN   Z,Z-farnesyl pyrophosphate synthase.
AN   Z,Z-FPP synthase.
AN   ZFPS.
CA   Dimethylallyl diphosphate + 2 isopentenyl diphosphate = 2 diphosphate +
CA   (2Z,6Z)-farnesyl diphosphate.
CC   -!- This enzyme, originally characterized from wild tomato, specifically
CC       forms (2Z,6Z)-farnesyl diphosphate via neryl diphosphate and
CC       isopentenyl diphosphate.
CC   -!- In wild tomato it is involved in the biosynthesis of several
CC       sesquiterpenes.
CC   -!- cf. EC 2.5.1.68 and EC 2.5.1.10.
DR   B8XA40, ZFPS_SOLHA ;
//
ID   2.5.1.93
DE   4-hydroxybenzoate geranyltransferase.
AN   4HB geranyltransferase.
AN   p-hydroxybenzoate geranyltransferase.
AN   PHB geranyltransferase.
CA   Geranyl diphosphate + 4-hydroxybenzoate = 3-geranyl-4-hydroxybenzoate +
CA   diphosphate.
CF   Magnesium.
CC   -!- The enzyme is involved in shikonin biosynthesis.
CC   -!- It has a strict substrate specificity for geranyl diphosphate.
DR   Q8W405, PGT1_LITER ;  Q8W404, PGT2_LITER ;
//
ID   2.5.1.94
DE   Adenosyl-chloride synthase.
AN   5'-chloro-5'-deoxyadenosine synthase.
AN   Chlorinase.
CA   S-adenosyl-L-methionine + chloride = 5-deoxy-5-chloroadenosine +
CA   L-methionine.
CC   -!- This enzyme, isolated from the marine bacterium Salinispora tropica,
CC       catalyzes an early step in the pathway leading to biosynthesis of the
CC       proteosome inhibitor salinosporamide A.
CC   -!- The enzyme is very similar to EC 2.5.1.63 but does not accept
CC       fluoride.
//
ID   2.5.1.n1
DE   Transferred entry: 2.2.1.9.
//
ID   2.5.1.n2
DE   Transferred entry: 2.5.1.81.
//
ID   2.5.1.n3
DE   Transferred entry: 2.5.1.73.
//
ID   2.6.1.1
DE   Aspartate transaminase.
AN   Aspartate aminotransferase.
AN   Glutamic--aspartic transaminase.
AN   Glutamic--oxaloacetic transaminase.
AN   Transaminase A.
CA   L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.
CC   -!- This activity can be formed from EC 2.6.1.57 by controlled
CC       proteolysis.
PR   PROSITE; PDOC00098;
DR   P46643, AAT1_ARATH ;  P53001, AAT1_BACSU ;  P28011, AAT1_MEDSA ;
DR   Q60317, AAT1_METJA ;  P85906, AAT1_PSEMZ ;  P46645, AAT2_ARATH ;
DR   P39643, AAT2_BACSU ;  Q58097, AAT2_METJA ;  P85951, AAT2_PSEMZ ;
DR   P46644, AAT3_ARATH ;  O07587, AAT3_BACSU ;  P46646, AAT4_ARATH ;
DR   P46248, AAT5_ARATH ;  Q02635, AATA_RHIME ;  P58350, AATB1_RHIME;
DR   Q06191, AATB2_RHIME;  P33097, AATC_BOVIN ;  Q22067, AATC_CAEEL ;
DR   P00504, AATC_CHICK ;  P28734, AATC_DAUCA ;  Q54SF7, AATC_DICDI ;
DR   P08906, AATC_HORSE ;  P17174, AATC_HUMAN ;  Q4R5L1, AATC_MACFA ;
DR   P05201, AATC_MOUSE ;  P37833, AATC_ORYSJ ;  A5A6K8, AATC_PANTR ;
DR   P00503, AATC_PIG   ;  Q5R691, AATC_PONAB ;  P12343, AATC_RABIT ;
DR   P13221, AATC_RAT   ;  O42652, AATC_SCHPO ;  P23542, AATC_YEAST ;
DR   P12344, AATM_BOVIN ;  P85310, AATM_CATRO ;  P00508, AATM_CHICK ;
DR   Q55F21, AATM_DICDI ;  P08907, AATM_HORSE ;  P00505, AATM_HUMAN ;
DR   P26563, AATM_LUPAN ;  Q4R559, AATM_MACFA ;  P05202, AATM_MOUSE ;
DR   P00506, AATM_PIG   ;  Q5REB0, AATM_PONAB ;  P12345, AATM_RABIT ;
DR   P00507, AATM_RAT   ;  O94320, AATM_SCHPO ;  Q28F67, AATM_XENTR ;
DR   Q01802, AATM_YEAST ;  O67781, AAT_AQUAE  ;  P23034, AAT_BACY2  ;
DR   P00509, AAT_ECOLI  ;  Q59228, AAT_GEOSE  ;  P44425, AAT_HAEIN  ;
DR   P52069, AAT_METEX  ;  P63499, AAT_MYCBO  ;  P63498, AAT_MYCTU  ;
DR   P72173, AAT_PSEAE  ;  Q9V0L2, AAT_PYRAB  ;  O58489, AAT_PYRHO  ;
DR   O93744, AAT_PYRKO  ;  O86459, AAT_RHILP  ;  Q1RGV0, AAT_RICBR  ;
DR   Q92JE7, AAT_RICCN  ;  Q4UND3, AAT_RICFE  ;  Q9ZE56, AAT_RICPR  ;
DR   Q68XV9, AAT_RICTY  ;  Q56114, AAT_SALTI  ;  P58661, AAT_SALTY  ;
DR   P36692, AAT_STRGR  ;  Q60013, AAT_STRVG  ;  Q4J8X2, AAT_SULAC  ;
DR   P14909, AAT_SULSO  ;  Q972A2, AAT_SULTO  ;  Q55128, AAT_SYNY3  ;
DR   O33822, AAT_THEAQ  ;  Q9X0Y2, AAT_THEMA  ;  Q56232, AAT_THET8  ;
DR   Q9SIE1, PAT_ARATH  ;  Q5F4K8, PAT_PINPS  ;  O85746, TYRB_KLEPN ;
//
ID   2.6.1.2
DE   Alanine transaminase.
AN   Alanine aminotransferase.
AN   Glutamic--alanine transaminase.
AN   Glutamic--pyruvic transaminase.
CA   L-alanine + 2-oxoglutarate = pyruvate + L-glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- 2-aminobutanoate acts slowly instead of alanine.
DR   P52894, ALA2_HORVU ;  P34106, ALA2_PANMI ;  Q54MJ7, ALAM_DICDI ;
DR   P52893, ALAM_YEAST ;  A4IFH5, ALAT1_BOVIN;  P24298, ALAT1_HUMAN;
DR   Q8QZR5, ALAT1_MOUSE;  P13191, ALAT1_PIG  ;  P25409, ALAT1_RAT  ;
DR   Q6NYL5, ALAT2_DANRE;  Q8TD30, ALAT2_HUMAN;  Q8BGT5, ALAT2_MOUSE;
DR   Q6GM82, ALAT2_XENLA;  Q28DB5, ALAT2_XENTR;  Q10334, ALAT_SCHPO ;
DR   P52892, ALAT_YEAST ;
//
ID   2.6.1.3
DE   Cysteine transaminase.
AN   Cysteine aminotransferase.
CA   L-cysteine + 2-oxoglutarate = mercaptopyruvate + L-glutamate.
CF   Pyridoxal 5'-phosphate.
//
ID   2.6.1.4
DE   Glycine transaminase.
AN   Glycine aminotransferase.
CA   Glycine + 2-oxoglutarate = glyoxylate + L-glutamate.
CF   Pyridoxal 5'-phosphate.
//
ID   2.6.1.5
DE   Tyrosine transaminase.
AN   TyrAT.
AN   Tyrosine aminotransferase.
CA   L-tyrosine + 2-oxoglutarate = 4-hydroxyphenylpyruvate + L-glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- L-phenylalanine can act instead of L-tyrosine.
CC   -!- The mitochondrial enzyme may be identical with EC 2.6.1.1.
CC   -!- The three isoenzymic forms are interconverted by EC 3.4.22.32 and
CC       EC 3.4.22.33.
CC   -!- The enzyme can also catalyze the final step in the methionine-salvage
CC       pathway of Klebsiella pneumoniae.
PR   PROSITE; PDOC00098;
DR   Q58CZ9, ATTY_BOVIN ;  Q54K95, ATTY_DICDI ;  P17735, ATTY_HUMAN ;
DR   Q8QZR1, ATTY_MOUSE ;  P04694, ATTY_RAT   ;  Q02636, ATTY_RHIME ;
DR   P33447, ATTY_TRYCR ;  Q9LVY1, TAT_ARATH  ;  O85746, TYRB_KLEPN ;
//
ID   2.6.1.6
DE   Leucine transaminase.
AN   Leucine aminotransferase.
CA   L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Differs from EC 2.6.1.42 in that it does not act on L-valine or
CC       L-isoleucine, although it does act on L-methionine.
//
ID   2.6.1.7
DE   Kynurenine--oxoglutarate transaminase.
AN   Kynurenine aminotransferase.
AN   Kynurenine--oxoglutarate aminotransferase.
CA   L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate +
CA   L-glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Also acts on 3-hydroxykynurenine.
CC   -!- The product 4-(2-aminophenyl)-2,4-dioxobutanoate is converted into
CC       kynurenate by a spontaneous reaction.
DR   Q5E9N4, AADAT_BOVIN;  Q8N5Z0, AADAT_HUMAN;  Q9WVM8, AADAT_MOUSE;
DR   Q64602, AADAT_RAT  ;  P47039, BNA3_YEAST ;  Q16773, KAT1_HUMAN ;
DR   Q8BTY1, KAT1_MOUSE ;  Q08415, KAT1_RAT   ;  Q0P5G4, KAT3_BOVIN ;
DR   Q7T3E5, KAT3_DANRE ;  Q6YP21, KAT3_HUMAN ;  Q71RI9, KAT3_MOUSE ;
DR   Q58FK9, KAT3_RAT   ;  Q54KM6, KAT_DICDI  ;
//
ID   2.6.1.8
DE   2,5-diaminovalerate transaminase.
AN   2,5-diaminovalerate aminotransferase.
AN   Diamino-acid aminotransferase.
CA   2,5-diaminopentanoate + 2-oxoglutarate = 5-amino-2-oxopentanoate +
CA   L-glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- 2,5-diaminoglutarate can act instead of diaminopentanoate.
//
ID   2.6.1.9
DE   Histidinol-phosphate transaminase.
AN   Histidinol-phosphate aminotransferase.
AN   Imidazole acetol-phosphate transaminase.
AN   Imidazolylacetolphosphate aminotransferase.
CA   L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl
CA   phosphate + L-glutamate.
CF   Pyridoxal 5'-phosphate.
PR   PROSITE; PDOC00518;
DR   Q3M504, HIS81_ANAVT;  O28277, HIS81_ARCFU;  Q81SV5, HIS81_BACAN;
DR   Q73AX7, HIS81_BACC1;  Q81FQ1, HIS81_BACCR;  Q63DL4, HIS81_BACCZ;
DR   Q6HL37, HIS81_BACHK;  Q7WHN5, HIS81_BORBR;  Q7W6Q1, HIS81_BORPA;
DR   Q7VWL5, HIS81_BORPE;  Q89GX0, HIS81_BRAJA;  Q62GE0, HIS81_BURMA;
DR   Q3JW89, HIS81_BURP1;  Q63XM1, HIS81_BURPS;  Q39K90, HIS81_BURS3;
DR   Q3AD52, HIS81_CARHZ;  Q9A671, HIS81_CAUCR;  Q46Y48, HIS81_CUPPJ;
DR   Q47GP2, HIS81_DECAR;  Q5FRR4, HIS81_GLUOX;  Q4QN73, HIS81_HAEI8;
DR   P44423, HIS81_HAEIN;  Q5QZ49, HIS81_IDILO;  Q5X5X0, HIS81_LEGPA;
DR   Q5ZW88, HIS81_LEGPH;  Q5WX92, HIS81_LEGPL;  Q65S79, HIS81_MANSM;
DR   Q609W4, HIS81_METCA;  Q82WM3, HIS81_NITEU;  Q2YAU6, HIS81_NITMU;
DR   Q3JEN8, HIS81_NITOC;  Q8YV89, HIS81_NOSS1;  Q8ESS3, HIS81_OCEIH;
DR   Q9CLM3, HIS81_PASMU;  Q9HVX0, HIS81_PSEAE;  Q4KI72, HIS81_PSEF5;
DR   Q3KHZ1, HIS81_PSEPF;  Q4FSH2, HIS81_PSYA2;  Q8XV80, HIS81_RALSO;
DR   Q987C8, HIS81_RHILO;  Q92MG0, HIS81_RHIME;  Q31I36, HIS81_THICR;
DR   Q3SK85, HIS81_THIDA;  Q3MAX6, HIS82_ANAVT;  O28255, HIS82_ARCFU;
DR   Q81P62, HIS82_BACAN;  Q736A5, HIS82_BACC1;  Q81C43, HIS82_BACCR;
DR   Q63A05, HIS82_BACCZ;  Q6HHF6, HIS82_BACHK;  Q7WDY3, HIS82_BORBR;
DR   Q7W2Y3, HIS82_BORPA;  Q7VSZ0, HIS82_BORPE;  Q89UL9, HIS82_BRAJA;
DR   Q62FC0, HIS82_BURMA;  Q3JMZ7, HIS82_BURP1;  Q63Q87, HIS82_BURPS;
DR   Q39CT7, HIS82_BURS3;  Q3AAT6, HIS82_CARHZ;  Q9A5B6, HIS82_CAUCR;
DR   Q46WL3, HIS82_CUPPJ;  Q47AL9, HIS82_DECAR;  Q5FQA6, HIS82_GLUOX;
DR   Q4QLD1, HIS82_HAEI8;  Q57004, HIS82_HAEIN;  Q5QWQ9, HIS82_IDILO;
DR   Q5X3Q5, HIS82_LEGPA;  Q5ZU10, HIS82_LEGPH;  Q5WV43, HIS82_LEGPL;
DR   Q65RB2, HIS82_MANSM;  Q608S3, HIS82_METCA;  Q82XE0, HIS82_NITEU;
DR   Q2Y6Y6, HIS82_NITMU;  Q3J7H2, HIS82_NITOC;  Q8YMG7, HIS82_NOSS1;
DR   Q8EQB9, HIS82_OCEIH;  Q9CMI7, HIS82_PASMU;  Q9HZ68, HIS82_PSEAE;
DR   Q4K8N0, HIS82_PSEF5;  Q3K8U2, HIS82_PSEPF;  Q4FQF9, HIS82_PSYA2;
DR   Q8Y0Y8, HIS82_RALSO;  Q98G10, HIS82_RHILO;  Q92L21, HIS82_RHIME;
DR   Q31GD4, HIS82_THICR;  Q3SI68, HIS82_THIDA;  Q39M27, HIS83_BURS3;
DR   Q98B00, HIS83_RHILO;  Q930J0, HIS83_RHIME;  P45358, HIS8_ACEPA ;
DR   A1TKZ0, HIS8_ACIAC ;  Q6FEC7, HIS8_ACIAD ;  B7GZI3, HIS8_ACIB3 ;
DR   B7I6C5, HIS8_ACIB5 ;  B2HTW5, HIS8_ACIBC ;  B0VV21, HIS8_ACIBS ;
DR   A3M2I8, HIS8_ACIBT ;  B0V7Q2, HIS8_ACIBY ;  A5FVN2, HIS8_ACICJ ;
DR   B9MDV4, HIS8_ACIET ;  A1W431, HIS8_ACISJ ;  A0KKB7, HIS8_AERHH ;
DR   A4SMP7, HIS8_AERS4 ;  Q8U9W3, HIS8_AGRT5 ;  B2UPR9, HIS8_AKKM8 ;
DR   B6EJ89, HIS8_ALISL ;  A8MEH2, HIS8_ALKOO ;  A7HCR6, HIS8_ANADF ;
DR   B7GHJ8, HIS8_ANOFW ;  O67857, HIS8_AQUAE ;  Q949X3, HIS8_ARATH ;
DR   A8EWM9, HIS8_ARCB4 ;  Q5P791, HIS8_AROAE ;  A1R558, HIS8_ARTAT ;
DR   A8HZS2, HIS8_AZOC5 ;  A7Z614, HIS8_BACA2 ;  A7GN55, HIS8_BACCN ;
DR   Q5LAZ9, HIS8_BACFN ;  Q64RE8, HIS8_BACFR ;  Q9KCA8, HIS8_BACHD ;
DR   Q65I37, HIS8_BACLD ;  Q8KZ92, HIS8_BACNA ;  A8FEJ6, HIS8_BACP2 ;
DR   Q5WGR9, HIS8_BACSK ;  P17731, HIS8_BACSU ;  Q8ABA8, HIS8_BACTN ;
DR   A6L2V8, HIS8_BACV8 ;  Q1LT68, HIS8_BAUCH ;  P60998, HIS8_BDEBA ;
DR   B2IDA4, HIS8_BEII9 ;  A1A2H6, HIS8_BIFAA ;  Q8G4S8, HIS8_BIFLO ;
DR   Q7VQW9, HIS8_BLOFL ;  Q492K2, HIS8_BLOPB ;  C0R1Z0, HIS8_BRAHW ;
DR   C0ZCE7, HIS8_BREBN ;  Q2YR81, HIS8_BRUA2 ;  Q57AR7, HIS8_BRUAB ;
DR   Q8YJK3, HIS8_BRUME ;  A5VSV7, HIS8_BRUO2 ;  Q8FY98, HIS8_BRUSU ;
DR   B8D8Q3, HIS8_BUCA5 ;  P57202, HIS8_BUCAI ;  Q9ZHE5, HIS8_BUCAP ;
DR   B8D707, HIS8_BUCAT ;  Q89AX7, HIS8_BUCBP ;  Q058A6, HIS8_BUCCC ;
DR   Q84I53, HIS8_BUCDN ;  Q84I52, HIS8_BUCMH ;  Q84I51, HIS8_BUCSC ;
DR   Q845V2, HIS8_BURM1 ;  A4XMY1, HIS8_CALS8 ;  A7ZCF3, HIS8_CAMC1 ;
DR   A7H084, HIS8_CAMC5 ;  A0RMN9, HIS8_CAMFF ;  A7I2V8, HIS8_CAMHC ;
DR   A8FKA6, HIS8_CAMJ8 ;  A7H556, HIS8_CAMJD ;  Q9PII2, HIS8_CAMJE ;
DR   A1VY36, HIS8_CAMJJ ;  Q5HWF4, HIS8_CAMJR ;  B9KDN6, HIS8_CAMLR ;
DR   P56099, HIS8_CANMA ;  B3PCJ2, HIS8_CELJU ;  Q3ARM7, HIS8_CHLCH ;
DR   B3ECG2, HIS8_CHLL2 ;  B3QP11, HIS8_CHLP8 ;  A1BGB4, HIS8_CHLPD ;
DR   Q8KD01, HIS8_CHLTE ;  Q1R089, HIS8_CHRSD ;  Q7P0F4, HIS8_CHRVO ;
DR   A8AEK3, HIS8_CITK8 ;  Q97ES6, HIS8_CLOAB ;  A7FU81, HIS8_CLOB1 ;
DR   C3KVX5, HIS8_CLOB6 ;  A6LUF3, HIS8_CLOB8 ;  A5I245, HIS8_CLOBH ;
DR   C1FN41, HIS8_CLOBJ ;  B1ILA9, HIS8_CLOBK ;  A7GDQ6, HIS8_CLOBL ;
DR   B8I5V1, HIS8_CLOCE ;  B9E168, HIS8_CLOK1 ;  A5N7Q7, HIS8_CLOK5 ;
DR   A0PXP5, HIS8_CLONN ;  Q47XB7, HIS8_COLP3 ;  P60999, HIS8_CORDI ;
DR   Q8FNZ1, HIS8_COREF ;  A4QFG6, HIS8_CORGB ;  Q9KJU4, HIS8_CORGL ;
DR   Q4JW58, HIS8_CORJK ;  B1WY56, HIS8_CYAA5 ;  B8HW95, HIS8_CYAP4 ;
DR   B7JUI4, HIS8_CYAP8 ;  Q11VM5, HIS8_CYTH3 ;  Q3Z879, HIS8_DEHE1 ;
DR   A5FR29, HIS8_DEHSB ;  Q3ZXL8, HIS8_DEHSC ;  Q9RRM7, HIS8_DEIRA ;
DR   Q311Z4, HIS8_DESDG ;  B8FP20, HIS8_DESHD ;  Q24QJ1, HIS8_DESHY ;
DR   Q6AQK2, HIS8_DESPS ;  Q72DA0, HIS8_DESVH ;  A1VEW4, HIS8_DESVV ;
DR   A8LK96, HIS8_DINSH ;  A7ZNJ3, HIS8_ECO24 ;  B7UT58, HIS8_ECO27 ;
DR   B7MDH5, HIS8_ECO45 ;  B7L9P8, HIS8_ECO55 ;  Q9S5G6, HIS8_ECO57 ;
DR   B5YU77, HIS8_ECO5E ;  B7NQG9, HIS8_ECO7I ;  B7MWU0, HIS8_ECO81 ;
DR   B7M400, HIS8_ECO8A ;  C4ZSB0, HIS8_ECOBW ;  B1X6V8, HIS8_ECODH ;
DR   A8A1P5, HIS8_ECOHS ;  A1ACN3, HIS8_ECOK1 ;  Q0TG66, HIS8_ECOL5 ;
DR   Q8FG51, HIS8_ECOL6 ;  B1IZ53, HIS8_ECOLC ;  P06986, HIS8_ECOLI ;
DR   B7NC61, HIS8_ECOLU ;  B6I848, HIS8_ECOSE ;  B1LP20, HIS8_ECOSM ;
DR   Q1RA52, HIS8_ECOUT ;  A4WC70, HIS8_ENT38 ;  A7MJP4, HIS8_ENTS8 ;
DR   Q6D410, HIS8_ERWCT ;  Q2N7G6, HIS8_ERYLH ;  B7LUF2, HIS8_ESCF3 ;
DR   A5FFY0, HIS8_FLAJ1 ;  A6GY79, HIS8_FLAPJ ;  B0TY45, HIS8_FRAP2 ;
DR   Q2J8K9, HIS8_FRASC ;  B5E9W9, HIS8_GEOBB ;  Q5KXV3, HIS8_GEOKA ;
DR   Q39YP6, HIS8_GEOMG ;  B9LZ53, HIS8_GEOSF ;  P61000, HIS8_GEOSL ;
DR   C6E916, HIS8_GEOSM ;  C5D3D2, HIS8_GEOSW ;  A4IQ80, HIS8_GEOTN ;
DR   A5G9G1, HIS8_GEOUR ;  Q7NL03, HIS8_GLOVI ;  A9H311, HIS8_GLUDA ;
DR   Q0BVW4, HIS8_GRABC ;  A0M287, HIS8_GRAFK ;  A5UA19, HIS8_HAEIE ;
DR   A5UGY2, HIS8_HAEIG ;  Q2SBJ7, HIS8_HAHCH ;  B9LNJ8, HIS8_HALLT ;
DR   Q5V4K3, HIS8_HALMA ;  B0R4Q4, HIS8_HALS3 ;  Q9HQS0, HIS8_HALSA ;
DR   P17736, HIS8_HALVD ;  Q18F03, HIS8_HALWD ;  Q7VIJ3, HIS8_HELHP ;
DR   B4U9L1, HIS8_HYDS0 ;  Q0C348, HIS8_HYPNA ;  Q28TL1, HIS8_JANSC ;
DR   B5XPE6, HIS8_KLEP3 ;  A6TBC4, HIS8_KLEP7 ;  B2GBR8, HIS8_LACF3 ;
DR   Q02135, HIS8_LACLA ;  A2RKS5, HIS8_LACLM ;  Q02YW3, HIS8_LACLS ;
DR   Q88UE6, HIS8_LACPL ;  Q04QW8, HIS8_LEPBJ ;  Q04Z75, HIS8_LEPBL ;
DR   Q72PG3, HIS8_LEPIC ;  Q8F6W9, HIS8_LEPIN ;  B1N009, HIS8_LEUCK ;
DR   Q03VY3, HIS8_LEUMM ;  Q92A83, HIS8_LISIN ;  C1KWM5, HIS8_LISMC ;
DR   Q71Y90, HIS8_LISMF ;  B8DC01, HIS8_LISMH ;  Q8Y5X8, HIS8_LISMO ;
DR   A0AK37, HIS8_LISW6 ;  B1HTD4, HIS8_LYSSC ;  B9EAC1, HIS8_MACCJ ;
DR   Q2W047, HIS8_MAGSA ;  Q0AM22, HIS8_MARMM ;  A6VUD3, HIS8_MARMS ;
DR   Q11DR9, HIS8_MESSB ;  A6UTL8, HIS8_META3 ;  Q8TUE9, HIS8_METAC ;
DR   Q46E46, HIS8_METBF ;  Q12U08, HIS8_METBU ;  O07131, HIS8_METFL ;
DR   B3DXN2, HIS8_METI4 ;  Q58365, HIS8_METJA ;  Q8TVG3, HIS8_METKA ;
DR   A2SSJ1, HIS8_METLZ ;  A4FWW1, HIS8_METM5 ;  A9AA96, HIS8_METM6 ;
DR   A6VGF6, HIS8_METM7 ;  Q8PX17, HIS8_METMA ;  A3CWS8, HIS8_METMJ ;
DR   P61003, HIS8_METMP ;  B8IRU5, HIS8_METNO ;  B8GIB0, HIS8_METPE ;
DR   A2SE05, HIS8_METPP ;  A5UKY0, HIS8_METS3 ;  B0UN04, HIS8_METS4 ;
DR   Q2NEQ0, HIS8_METST ;  O27624, HIS8_METTH ;  A6UPL6, HIS8_METVS ;
DR   B0JJJ7, HIS8_MICAN ;  Q2RL44, HIS8_MOOTA ;  A0QHI1, HIS8_MYCA1 ;
DR   P0A679, HIS8_MYCBO ;  A1KJ16, HIS8_MYCBP ;  C1ANM2, HIS8_MYCBT ;
DR   B8ZRB0, HIS8_MYCLB ;  Q9X7B8, HIS8_MYCLE ;  B2HQA3, HIS8_MYCMM ;
DR   P61001, HIS8_MYCPA ;  A0QX82, HIS8_MYCS2 ;  A3Q130, HIS8_MYCSJ ;
DR   A1UHK7, HIS8_MYCSK ;  P28735, HIS8_MYCSM ;  Q1B7G5, HIS8_MYCSS ;
DR   A5U2V6, HIS8_MYCTA ;  P0A678, HIS8_MYCTU ;  A0PP15, HIS8_MYCUA ;
DR   A1T8W2, HIS8_MYCVP ;  Q3IRT1, HIS8_NATPD ;  Q5F7D7, HIS8_NEIG1 ;
DR   B4RJ05, HIS8_NEIG2 ;  A9M185, HIS8_NEIM0 ;  Q9JTH8, HIS8_NEIMA ;
DR   Q9JYH7, HIS8_NEIMB ;  A1KV06, HIS8_NEIMF ;  Q9FEW2, HIS8_NICPL ;
DR   Q1QQD5, HIS8_NITHX ;  A6Q1Z5, HIS8_NITSB ;  Q3SV41, HIS8_NITWN ;
DR   Q5YYP9, HIS8_NOCFA ;  Q2GAI1, HIS8_NOVAD ;  A6LAM2, HIS8_PARD8 ;
DR   Q51687, HIS8_PARDP ;  C6DF75, HIS8_PECCP ;  Q3A7R3, HIS8_PELCD ;
DR   Q3B3L3, HIS8_PELLD ;  B4SGL8, HIS8_PELPB ;  A5CZ78, HIS8_PELTS ;
DR   Q4FP52, HIS8_PELUB ;  Q7N6I1, HIS8_PHOLL ;  Q6LT75, HIS8_PHOPR ;
DR   A1VK38, HIS8_POLNA ;  B4S8L6, HIS8_PROA2 ;  Q6A8L4, HIS8_PROAC ;
DR   A4SE60, HIS8_PROVI ;  Q48ED0, HIS8_PSE14 ;  Q15RU8, HIS8_PSEA6 ;
DR   Q1IE97, HIS8_PSEE4 ;  A5VZ57, HIS8_PSEP1 ;  B0KQJ6, HIS8_PSEPG ;
DR   Q88P86, HIS8_PSEPK ;  B1JBC0, HIS8_PSEPW ;  Q87WV6, HIS8_PSESM ;
DR   Q9RI00, HIS8_PSEST ;  Q4ZNW0, HIS8_PSEU2 ;  Q8TH25, HIS8_PYRFU ;
DR   Q5JFU6, HIS8_PYRKO ;  P55683, HIS8_RHISN ;  Q7UNC3, HIS8_RHOBA ;
DR   B6IYQ0, HIS8_RHOCS ;  C1ATZ5, HIS8_RHOOB ;  Q2IS68, HIS8_RHOP2 ;
DR   Q07IG8, HIS8_RHOP5 ;  P61002, HIS8_RHOPA ;  Q20YH9, HIS8_RHOPB ;
DR   Q131B9, HIS8_RHOPS ;  B3Q8Z5, HIS8_RHOPT ;  Q2RP86, HIS8_RHORT ;
DR   A3PIA4, HIS8_RHOS1 ;  Q3J445, HIS8_RHOS4 ;  A4WUN9, HIS8_RHOS5 ;
DR   B9KPH4, HIS8_RHOSK ;  Q0SHX9, HIS8_RHOSR ;  A7NFV2, HIS8_ROSCS ;
DR   Q163G3, HIS8_ROSDO ;  A5V022, HIS8_ROSS1 ;  Q1AY33, HIS8_RUBXD ;
DR   B5EX40, HIS8_SALA4 ;  A9ML15, HIS8_SALAR ;  Q57MS2, HIS8_SALCH ;
DR   B5FM42, HIS8_SALDC ;  B5QZL3, HIS8_SALEP ;  B5RBR3, HIS8_SALG2 ;
DR   B4T9N5, HIS8_SALHS ;  B4SX42, HIS8_SALNS ;  Q5PDP4, HIS8_SALPA ;
DR   A9MSC2, HIS8_SALPB ;  C0Q1K1, HIS8_SALPC ;  B5BFB9, HIS8_SALPK ;
DR   B4TMR6, HIS8_SALSV ;  Q8Z5J9, HIS8_SALTI ;  P10369, HIS8_SALTY ;
DR   P36605, HIS8_SCHPO ;  A8GC78, HIS8_SERP5 ;  A1S6Z2, HIS8_SHEAM ;
DR   Q8EFB2, HIS8_SHEON ;  B2TYF9, HIS8_SHIB3 ;  Q323J1, HIS8_SHIBS ;
DR   Q32EF0, HIS8_SHIDS ;  Q0T3A6, HIS8_SHIF8 ;  Q83KJ6, HIS8_SHIFL ;
DR   Q3Z0G4, HIS8_SHISS ;  Q5LNM6, HIS8_SILPO ;  Q1GET3, HIS8_SILST ;
DR   Q2NTX2, HIS8_SODGM ;  Q1GP30, HIS8_SPHAL ;  A7WZL0, HIS8_STAA1 ;
DR   A6TZK2, HIS8_STAA2 ;  Q2FIR7, HIS8_STAA3 ;  Q2G087, HIS8_STAA8 ;
DR   A5IQS7, HIS8_STAA9 ;  Q2YSI3, HIS8_STAAB ;  Q5HHU9, HIS8_STAAC ;
DR   A6QF32, HIS8_STAAE ;  P67724, HIS8_STAAM ;  P67725, HIS8_STAAN ;
DR   Q6GIR8, HIS8_STAAR ;  Q6GBA6, HIS8_STAAS ;  A8YZZ5, HIS8_STAAT ;
DR   Q8NXN3, HIS8_STAAW ;  B9DK21, HIS8_STACT ;  Q5HR08, HIS8_STAEQ ;
DR   Q8CTG8, HIS8_STAES ;  Q4L4E7, HIS8_STAHJ ;  Q49VS0, HIS8_STAS1 ;
DR   Q82AA5, HIS8_STRAW ;  P16246, HIS8_STRCO ;  A8AY31, HIS8_STRGC ;
DR   B4STN8, HIS8_STRM5 ;  B2FPM0, HIS8_STRMK ;  Q8DTQ4, HIS8_STRMU ;
DR   A3CNT7, HIS8_STRSV ;  Q03K75, HIS8_STRTD ;  Q30TC9, HIS8_SULDN ;
DR   A6QBY8, HIS8_SULNB ;  O33770, HIS8_SULSO ;  Q970Z4, HIS8_SULTO ;
DR   Q67KI2, HIS8_SYMTH ;  Q2LST8, HIS8_SYNAS ;  Q31PF9, HIS8_SYNE7 ;
DR   Q2JTG5, HIS8_SYNJA ;  Q2JPM4, HIS8_SYNJB ;  Q5N4R3, HIS8_SYNP6 ;
DR   P73807, HIS8_SYNY3 ;  Q8DM42, HIS8_THEEB ;  Q47QS8, HIS8_THEFY ;
DR   C5A7A4, HIS8_THEGJ ;  Q9X0D0, HIS8_THEMA ;  B9K9R9, HIS8_THENN ;
DR   A5INE2, HIS8_THEP1 ;  B0K735, HIS8_THEP3 ;  B0K625, HIS8_THEPX ;
DR   B1L869, HIS8_THESQ ;  Q8R5Q4, HIS8_THETN ;  Q9L6I2, HIS8_THIRO ;
DR   O82030, HIS8_TOBAC ;  Q10VS0, HIS8_TRIEI ;  Q0W253, HIS8_UNCMA ;
DR   A5CVR5, HIS8_VESOH ;  A5F2A2, HIS8_VIBC3 ;  Q9KSX2, HIS8_VIBCH ;
DR   C3LU31, HIS8_VIBCM ;  Q5E637, HIS8_VIBF1 ;  B5FDA0, HIS8_VIBFM ;
DR   A7MX17, HIS8_VIBHB ;  Q87QL0, HIS8_VIBPA ;  Q8D8Q1, HIS8_VIBVU ;
DR   Q7MLS5, HIS8_VIBVY ;  Q7M7Y6, HIS8_WOLSU ;  P58891, HIS8_XANAC ;
DR   Q3BUF6, HIS8_XANC5 ;  Q4UU41, HIS8_XANC8 ;  B0RSL5, HIS8_XANCB ;
DR   P58892, HIS8_XANCP ;  Q2P3K2, HIS8_XANOM ;  Q5H0L0, HIS8_XANOR ;
DR   A7ICA9, HIS8_XANP2 ;  B2I5Y0, HIS8_XYLF2 ;  Q9PBC6, HIS8_XYLFA ;
DR   B0U3B2, HIS8_XYLFM ;  Q87C30, HIS8_XYLFT ;  P07172, HIS8_YEAST ;
DR   A1JTV9, HIS8_YERE8 ;  A7FJH1, HIS8_YERP3 ;  Q1C9R1, HIS8_YERPA ;
DR   B2JZM8, HIS8_YERPB ;  Q8ZFX6, HIS8_YERPE ;  A9R2K5, HIS8_YERPG ;
DR   Q1CGX0, HIS8_YERPN ;  A4TKK4, HIS8_YERPP ;  Q66C50, HIS8_YERPS ;
DR   B1JPW1, HIS8_YERPY ;  P34037, HIS8_ZYMMO ;
//
ID   2.6.1.10
DE   Transferred entry: 2.6.1.21.
//
ID   2.6.1.11
DE   Acetylornithine transaminase.
AN   Acetylornithine 5-aminotransferase.
AN   Acetylornithine aminotransferase.
AN   Acetylornithine delta-transaminase.
AN   ACOAT.
AN   N(2)-acetylornithine 5-transaminase.
AN   N-acetylornithine aminotransferase.
AN   N-acetylornithine-delta-transaminase.
AN   Succinylornithine aminotransferase.
CA   N(2)-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate
CA   5-semialdehyde + L-glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Also acts on L-ornithine and N(2)-succinyl-L-ornithine.
PR   PROSITE; PDOC00519;
DR   Q7WKW5, ARGD1_BORBR;  Q7W7H6, ARGD1_BORPA;  Q7VTJ7, ARGD1_BORPE;
DR   Q89VE9, ARGD1_BRAJA;  Q885K0, ARGD1_PSESM;  Q7WDN7, ARGD2_BORBR;
DR   Q7W2N9, ARGD2_BORPA;  Q7VSH3, ARGD2_BORPE;  Q89LG2, ARGD2_BRAJA;
DR   Q882K8, ARGD2_PSESM;  Q9YBY6, ARGD_AERPE ;  Q8UI71, ARGD_AGRT5 ;
DR   O04866, ARGD_ALNGL ;  O66442, ARGD_AQUAE ;  Q9M8M7, ARGD_ARATH ;
DR   O30156, ARGD_ARCFU ;  Q75AW1, ARGD_ASHGO ;  Q9ZJ10, ARGD_BACAM ;
DR   Q81M98, ARGD_BACAN ;  Q818W2, ARGD_BACCR ;  Q9K8V5, ARGD_BACHD ;
DR   P36839, ARGD_BACSU ;  P59315, ARGD_BIFLO ;  P63566, ARGD_BRUME ;
DR   P63567, ARGD_BRUSU ;  P57600, ARGD_BUCAI ;  P59086, ARGD_BUCAP ;
DR   Q9PIR7, ARGD_CAMJE ;  Q6FXA4, ARGD_CANGA ;  Q9A652, ARGD_CAUCR ;
DR   P59316, ARGD_CHLTE ;  Q97GH9, ARGD_CLOAB ;  Q8FTN2, ARGD_COREF ;
DR   Q59282, ARGD_CORGL ;  Q6BUP9, ARGD_DEBHA ;  Q9RW75, ARGD_DEIRA ;
DR   Q55DT8, ARGD_DICDI ;  Q8X4S6, ARGD_ECO57 ;  P59317, ARGD_ECOL6 ;
DR   P18335, ARGD_ECOLI ;  Q07907, ARGD_GEOSE ;  Q7NN66, ARGD_GLOVI ;
DR   Q7VMS5, ARGD_HAEDU ;  O14433, ARGD_KLULA ;  Q9CHD3, ARGD_LACLA ;
DR   O08321, ARGD_LACPL ;  Q72RH8, ARGD_LEPIC ;  P24087, ARGD_LEPIN ;
DR   Q92BC0, ARGD_LISIN ;  Q71Z79, ARGD_LISMF ;  Q8Y6U4, ARGD_LISMO ;
DR   Q8TUE8, ARGD_METAC ;  Q58131, ARGD_METJA ;  Q8TUZ5, ARGD_METKA ;
DR   Q8PX16, ARGD_METMA ;  O27392, ARGD_METTH ;  P63569, ARGD_MYCBO ;
DR   Q9CC12, ARGD_MYCLE ;  A0QYS9, ARGD_MYCS2 ;  P63568, ARGD_MYCTU ;
DR   P59318, ARGD_MYXXA ;  Q9JTX9, ARGD_NEIMA ;  Q9JYY4, ARGD_NEIMB ;
DR   Q9P3I3, ARGD_NEUCR ;  Q82UP3, ARGD_NITEU ;  P54752, ARGD_NOSS1 ;
DR   Q8CUM9, ARGD_OCEIH ;  Q9CNT1, ARGD_PASMU ;  Q7N9E5, ARGD_PHOLL ;
DR   Q7VAS9, ARGD_PROMA ;  Q7V8L1, ARGD_PROMM ;  Q7V0G0, ARGD_PROMP ;
DR   P59319, ARGD_PSEPK ;  Q9V1I4, ARGD_PYRAB ;  Q8ZV07, ARGD_PYRAE ;
DR   Q8U0B4, ARGD_PYRFU ;  O59401, ARGD_PYRHO ;  Q5JFW3, ARGD_PYRKO ;
DR   Q8XWN8, ARGD_RALSO ;  Q98BB7, ARGD_RHILO ;  Q92SA0, ARGD_RHIME ;
DR   P30900, ARGD_RHOCB ;  Q8Z1Z3, ARGD_SALTI ;  P40732, ARGD_SALTY ;
DR   O74548, ARGD_SCHPO ;  P59320, ARGD_SHEON ;  P59321, ARGD_SHIFL ;
DR   Q5HP24, ARGD_STAEQ ;  Q8CSG1, ARGD_STAES ;  Q828A3, ARGD_STRAW ;
DR   Q9LCS5, ARGD_STRCL ;  Q9L1A4, ARGD_STRCO ;  Q59928, ARGD_STRMU ;
DR   Q7SI94, ARGD_SULSO ;  Q976K0, ARGD_SULTO ;  Q7U5R5, ARGD_SYNPX ;
DR   P73133, ARGD_SYNY3 ;  P59322, ARGD_THEEB ;  Q9X2A5, ARGD_THEMA ;
DR   Q93R93, ARGD_THET2 ;  Q5SHH5, ARGD_THET8 ;  Q8R7C1, ARGD_THETN ;
DR   Q9KNW2, ARGD_VIBCH ;  Q87L20, ARGD_VIBPA ;  P59323, ARGD_VIBVU ;
DR   Q7MH19, ARGD_VIBVY ;  Q7MAE6, ARGD_WOLSU ;  Q8PH31, ARGD_XANAC ;
DR   Q8P5Q4, ARGD_XANCP ;  Q9PDF2, ARGD_XYLFA ;  Q87DM8, ARGD_XYLFT ;
DR   Q6C846, ARGD_YARLI ;  P18544, ARGD_YEAST ;  P59324, ARGD_YERPE ;
DR   O30508, ARUC_PSEAE ;
//
ID   2.6.1.12
DE   Alanine--oxo-acid transaminase.
AN   Alanine--oxo-acid aminotransferase.
CA   L-alanine + a 2-oxo acid = pyruvate + an L-amino acid.
CF   Pyridoxal 5'-phosphate.
//
ID   2.6.1.13
DE   Ornithine aminotransferase.
AN   L-ornithine 5-aminotransferase.
AN   L-ornithine aminotransferase.
AN   Ornithine 5-aminotransferase.
AN   Ornithine delta-transaminase.
AN   Ornithine ketoacid aminotransferase.
AN   Ornithine transaminase.
AN   Ornithine--2-oxoacid aminotransferase.
AN   Ornithine--alpha-ketoglutarate aminotransferase.
AN   Ornithine--keto acid aminotransferase.
AN   Ornithine--keto acid transaminase.
AN   Ornithine--ketoglutarate aminotransferase.
AN   Ornithine--oxo acid aminotransferase.
AN   Ornithine--oxo-acid transaminase.
CA   L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino
CA   acid.
CF   Pyridoxal 5'-phosphate.
PR   PROSITE; PDOC00519;
DR   Q5HJI8, OAT1_STAAC ;  P60295, OAT1_STAAM ;  P60296, OAT1_STAAN ;
DR   Q6GKC1, OAT1_STAAR ;  Q6GCU1, OAT1_STAAS ;  Q8NYM5, OAT1_STAAW ;
DR   Q4A0N2, OAT1_STAS1 ;  Q5HHC8, OAT2_STAAC ;  P60297, OAT2_STAAM ;
DR   P60298, OAT2_STAAN ;  Q6GID1, OAT2_STAAR ;  Q6GAW9, OAT2_STAAS ;
DR   P60299, OAT2_STAAW ;  Q49W96, OAT2_STAS1 ;  C3P3K3, OAT_BACAA  ;
DR   C3LBX0, OAT_BACAC  ;  Q81TV3, OAT_BACAN  ;  C1EL61, OAT_BACC3  ;
DR   B9ITF9, OAT_BACCQ  ;  Q81GP2, OAT_BACCR  ;  Q9K5Z2, OAT_BACHD  ;
DR   P38021, OAT_BACSU  ;  Q7WP51, OAT_BORBR  ;  Q7W1E4, OAT_BORPA  ;
DR   Q7VSA0, OAT_BORPE  ;  Q3ZCF5, OAT_BOVIN  ;  Q89RB7, OAT_BRAJA  ;
DR   C0ZBR4, OAT_BREBN  ;  Q18040, OAT_CAEEL  ;  Q54JP5, OAT_DICDI  ;
DR   P49724, OAT_DROAN  ;  Q9VW26, OAT_DROME  ;  Q92413, OAT_EMENI  ;
DR   C4L2E7, OAT_EXISA  ;  C5D6R2, OAT_GEOSW  ;  P04181, OAT_HUMAN  ;
DR   B9EAM9, OAT_MACCJ  ;  P29758, OAT_MOUSE  ;  Q8EP32, OAT_OCEIH  ;
DR   Q4XWV5, OAT_PLACH  ;  Q6LFH8, OAT_PLAF7  ;  Q07805, OAT_PLAFD  ;
DR   Q7RT90, OAT_PLAYO  ;  P04182, OAT_RAT    ;  Q9P7L5, OAT_SCHPO  ;
DR   B9DIU0, OAT_STACT  ;  Q5HQK4, OAT_STAEQ  ;  Q8CT82, OAT_STAES  ;
DR   P31893, OAT_VIGAC  ;  P07991, OAT_YEAST  ;
//
ID   2.6.1.14
DE   Asparagine--oxo-acid transaminase.
AN   Asparagine--oxo-acid aminotransferase.
CA   L-asparagine + a 2-oxo acid = 2-oxosuccinamate + an amino acid.
CF   Pyridoxal 5'-phosphate.
//
ID   2.6.1.15
DE   Glutamine--pyruvate transaminase.
AN   Glutaminase II.
AN   Glutamine transaminase L.
AN   Glutamine--oxo-acid transaminase.
AN   Glutamine--pyruvate aminotransferase.
CA   L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine.
CF   Pyridoxal 5'-phosphate.
CC   -!- L-methionine can act as donor.
CC   -!- Glyoxylate can act as acceptor.
//
ID   2.6.1.16
DE   Glutamine--fructose-6-phosphate transaminase (isomerizing).
AN   D-fructose-6-phosphate amidotransferase.
AN   GlcN6P synthase.
AN   Glucosamine--fructose-6-phosphate aminotransferase (isomerizing).
AN   Glucosamine-6-phosphate isomerase (glutamine-forming).
AN   Glucosamine-6-phosphate synthase.
AN   Hexosephosphate aminotransferase.
AN   L-glutamine-D-fructose-6-phosphate amidotransferase.
CA   L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine
CA   6-phosphate.
CC   -!- Although the overall reaction is that of a transferase, the mechanism
CC       involves the formation of ketimine between fructose 6-phosphate and a
CC       6-amino group from a lysine residue at the active site, which is
CC       subsequently displaced by ammonia (transamidination).
CC   -!- Formerly EC 5.3.1.19.
PR   PROSITE; PDOC00406;
PR   PROSITE; PDOC51464;
DR   P53704, GFA1_CANAL ;  Q8SRI2, GFA1_ENCCU ;  Q09740, GFA1_SCHPO ;
DR   P14742, GFA1_YEAST ;  Q7T6X6, GFAT_MIMIV ;  Q06210, GFPT1_HUMAN;
DR   P47856, GFPT1_MOUSE;  P82808, GFPT1_RAT  ;  Q08DQ2, GFPT2_BOVIN;
DR   O94808, GFPT2_HUMAN;  Q9Z2Z9, GFPT2_MOUSE;  Q4KMC4, GFPT2_RAT  ;
DR   Q6F6U8, GLMS_ACIAD ;  Q9YCQ6, GLMS_AERPE ;  Q8UEH1, GLMS_AGRT5 ;
DR   O66648, GLMS_AQUAE ;  Q81VN5, GLMS_BACAN ;  Q73F49, GLMS_BACC1 ;
DR   Q81J01, GLMS_BACCR ;  Q9KG45, GLMS_BACHD ;  Q6HPL2, GLMS_BACHK ;
DR   Q65P46, GLMS_BACLD ;  E0U070, GLMS_BACPZ ;  Q5WLG7, GLMS_BACSK ;
DR   P0CI73, GLMS_BACSU ;  Q8AAB1, GLMS_BACTN ;  Q6G322, GLMS_BARHE ;
DR   Q6FZH6, GLMS_BARQU ;  Q7WE36, GLMS_BORBR ;  Q7W334, GLMS_BORPA ;
DR   Q7VRZ3, GLMS_BORPE ;  P59362, GLMS_BRAJA ;  Q577Y1, GLMS_BRUAB ;
DR   Q8YC47, GLMS_BRUME ;  Q8CY30, GLMS_BRUSU ;  P57138, GLMS_BUCAI ;
DR   Q8KA75, GLMS_BUCAP ;  P59499, GLMS_BUCBP ;  Q9PMT4, GLMS_CAMJE ;
DR   Q9ABV2, GLMS_CAUCR ;  Q5L589, GLMS_CHLAB ;  Q821Z7, GLMS_CHLCV ;
DR   Q9PLA4, GLMS_CHLMU ;  Q9Z6U0, GLMS_CHLPN ;  Q8KG38, GLMS_CHLTE ;
DR   O84823, GLMS_CHLTR ;  Q97MN6, GLMS_CLOAB ;  Q8XHZ7, GLMS_CLOPE ;
DR   Q890U2, GLMS_CLOTE ;  Q6NG33, GLMS_CORDI ;  Q8FNH2, GLMS_COREF ;
DR   Q8NND3, GLMS_CORGL ;  O19908, GLMS_CYACA ;  Q8XEG2, GLMS_ECO57 ;
DR   Q8FBT4, GLMS_ECOL6 ;  P17169, GLMS_ECOLI ;  Q6CYJ9, GLMS_ERWCT ;
DR   Q5NHQ9, GLMS_FRATT ;  Q8RG65, GLMS_FUSNN ;  Q5L3P0, GLMS_GEOKA ;
DR   Q74GH6, GLMS_GEOSL ;  Q7NIG8, GLMS_GLOVI ;  Q5FUY5, GLMS_GLUOX ;
DR   Q7VKK4, GLMS_HAEDU ;  P44708, GLMS_HAEIN ;  Q9HT00, GLMS_HALSA ;
DR   Q9ZJ94, GLMS_HELPJ ;  O26060, GLMS_HELPY ;  Q5QZH5, GLMS_IDILO ;
DR   Q9CGT6, GLMS_LACLA ;  Q88YE7, GLMS_LACPL ;  Q5X153, GLMS_LEGPA ;
DR   Q5ZRP4, GLMS_LEGPH ;  Q5WSX8, GLMS_LEGPL ;  Q6AD32, GLMS_LEIXX ;
DR   Q72V57, GLMS_LEPIC ;  Q8EZQ1, GLMS_LEPIN ;  Q92DS8, GLMS_LISIN ;
DR   Q722H1, GLMS_LISMF ;  Q8Y915, GLMS_LISMO ;  Q8TLL3, GLMS_METAC ;
DR   Q58815, GLMS_METJA ;  Q8TZ14, GLMS_METKA ;  Q8Q038, GLMS_METMA ;
DR   Q6LWM9, GLMS_METMP ;  O26273, GLMS_METTH ;  P0A589, GLMS_MYCBO ;
DR   P40831, GLMS_MYCLE ;  Q73S23, GLMS_MYCPA ;  O68956, GLMS_MYCS2 ;
DR   P0A588, GLMS_MYCTU ;  Q5F584, GLMS_NEIG1 ;  Q9JWN9, GLMS_NEIMA ;
DR   Q9K1P9, GLMS_NEIMB ;  O68280, GLMS_NOSS9 ;  Q8ETM5, GLMS_OCEIH ;
DR   P57963, GLMS_PASMU ;  Q7NA97, GLMS_PHOLL ;  Q6LLH3, GLMS_PHOPR ;
DR   Q9HT25, GLMS_PSEAE ;  Q88BX8, GLMS_PSEPK ;  Q87TT8, GLMS_PSESM ;
DR   Q9V249, GLMS_PYRAB ;  Q8ZTZ0, GLMS_PYRAE ;  Q8U4D1, GLMS_PYRFU ;
DR   O57981, GLMS_PYRHO ;  Q5JH71, GLMS_PYRKO ;  Q8Y303, GLMS_RALSO ;
DR   Q98LX5, GLMS_RHILO ;  Q92PS4, GLMS_RHIME ;  Q5PKV9, GLMS_SALPA ;
DR   Q8Z2Q2, GLMS_SALTI ;  Q8ZKX1, GLMS_SALTY ;  Q8CX33, GLMS_SHEON ;
DR   Q83IY4, GLMS_SHIFL ;  Q56206, GLMS_SPHYA ;  Q5HE49, GLMS_STAAC ;
DR   P64227, GLMS_STAAM ;  P64228, GLMS_STAAN ;  Q6GES3, GLMS_STAAR ;
DR   Q6G7F8, GLMS_STAAS ;  Q8NVE6, GLMS_STAAW ;  Q5HM69, GLMS_STAEQ ;
DR   Q8CRL1, GLMS_STAES ;  Q8E5P8, GLMS_STRA3 ;  Q8DZZ7, GLMS_STRA5 ;
DR   O86781, GLMS_STRCO ;  Q8DTY0, GLMS_STRMU ;  Q99ZD3, GLMS_STRP1 ;
DR   P0DB32, GLMS_STRP3 ;  Q5XBV6, GLMS_STRP6 ;  Q8P0S7, GLMS_STRP8 ;
DR   Q97SQ9, GLMS_STRPN ;  P0DB33, GLMS_STRPQ ;  Q8DRA8, GLMS_STRR6 ;
DR   Q4J6D9, GLMS_SULAC ;  Q67T12, GLMS_SYMTH ;  P72720, GLMS_SYNY3 ;
DR   Q8DJI6, GLMS_THEEB ;  Q9WXZ5, GLMS_THEMA ;  Q72HF4, GLMS_THET2 ;
DR   Q56213, GLMS_THET8 ;  Q8R841, GLMS_THETN ;  Q56275, GLMS_THIFE ;
DR   O83833, GLMS_TREPA ;  Q83IA1, GLMS_TROW8 ;  Q83FU2, GLMS_TROWT ;
DR   Q9KUM8, GLMS_VIBCH ;  Q5E279, GLMS_VIBF1 ;  Q87SR3, GLMS_VIBPA ;
DR   Q8DEF3, GLMS_VIBVU ;  Q7MP62, GLMS_VIBVY ;  Q8D3J0, GLMS_WIGBR ;
DR   Q8PGH9, GLMS_XANAC ;  Q8PCY1, GLMS_XANCP ;  Q9PH05, GLMS_XYLFA ;
DR   Q87F28, GLMS_XYLFT ;  Q8Z9S8, GLMS_YERPE ;  Q663R1, GLMS_YERPS ;
DR   Q5NRH4, GLMS_ZYMMO ;  Q92ZK3, NODM1_RHIME;  P25195, NODM2_RHIME;
DR   P94323, NODM_BRAJA ;  Q52846, NODM_RHILT ;  P08633, NODM_RHILV ;
DR   B3LLX6, YM084_YEAS1;  C7GL41, YM084_YEAS2;  A6ZME2, YM084_YEAS7;
DR   C8ZET7, YM084_YEAS8;  A2P2R3, YM084_YEAST;
//
ID   2.6.1.17
DE   Succinyldiaminopimelate transaminase.
AN   Succinyldiaminopimelate aminotransferase.
AN   Succinyldiaminopimelate transferase.
CA   N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2-
CA   L-amino-6-oxoheptanedioate + L-glutamate.
CF   Pyridoxal 5'-phosphate.
PR   PROSITE; PDOC00094;
DR   P57600, ARGD_BUCAI ;  P59086, ARGD_BUCAP ;  Q8X4S6, ARGD_ECO57 ;
DR   P59317, ARGD_ECOL6 ;  P18335, ARGD_ECOLI ;  Q7N9E5, ARGD_PHOLL ;
DR   Q8Z1Z3, ARGD_SALTI ;  P40732, ARGD_SALTY ;  P59321, ARGD_SHIFL ;
DR   P59324, ARGD_YERPE ;
//
ID   2.6.1.18
DE   Beta-alanine--pyruvate transaminase.
AN   Beta-alanine--pyruvate aminotransferase.
AN   Omega-amino acid--pyruvate aminotransferase.
CA   L-alanine + 3-oxopropanoate = pyruvate + beta-alanine.
CF   Pyridoxal 5'-phosphate.
DR   P28269, OAPT_PSEPU ;
//
ID   2.6.1.19
DE   4-aminobutyrate transaminase.
AN   4-aminobutyrate aminotransferase.
AN   Beta-alanine--oxoglutarate aminotransferase.
AN   GABA transaminase.
AN   Gamma-amino-N-butyrate transaminase.
CA   4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate.
CC   -!- Some preparations also act on beta-alanine, 5-aminopentanoate and
CC       (R,S)-3-amino-2-methylpropanoate.
PR   PROSITE; PDOC00519;
DR   P94427, GABT_BACSU ;  Q9BGI0, GABT_BOVIN ;  Q21217, GABT_CAEEL ;
DR   Q55FI1, GABT_DICDI ;  P22256, GABT_ECOLI ;  P80404, GABT_HUMAN ;
DR   P61922, GABT_MOUSE ;  P63505, GABT_MYCBO ;  P40829, GABT_MYCLE ;
DR   P63504, GABT_MYCTU ;  P80147, GABT_PIG   ;  P50554, GABT_RAT   ;
DR   P14010, GATA_EMENI ;  O13837, GATA_SCHPO ;  P49604, GATA_USTMA ;
DR   P17649, GATA_YEAST ;  P50457, PUUE_ECOLI ;
//
ID   2.6.1.20
DE   Deleted entry.
//
ID   2.6.1.21
DE   D-amino-acid transaminase.
AN   D-alanine aminotransferase.
AN   D-alanine transaminase.
AN   D-alanine-D-glutamate transaminase.
AN   D-amino acid aminotransferase.
AN   D-amino acid transaminase.
AN   D-aspartate aminotransferase.
AN   D-aspartate transaminase.
AN   D-aspartic aminotransferase.
CA   D-alanine + 2-oxoglutarate = pyruvate + D-glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- The enzyme from thermophilic Bacillus species acts on many D-amino
CC       acids with D-alanine and D-2-aminobutyrate as the best amino donors.
CC   -!- It can similarly use any of several 2-oxo acids as amino acceptor,
CC       with 2-oxoglutarate and 2-oxobutyrate among the best.
CC   -!- The enzyme from some other sources has a broader specificity.
CC   -!- Formerly EC 2.6.1.10.
PR   PROSITE; PDOC00618;
DR   P54692, DAAA_BACLI ;  O07597, DAAA_BACSU ;  P19938, DAAA_BACYM ;
DR   Q92B90, DAAA_LISIN ;  Q71Z49, DAAA_LISMF ;  O85046, DAAA_LISMO ;
DR   P54693, DAAA_LYSSH ;  Q5HF24, DAAA_STAAC ;  P63511, DAAA_STAAM ;
DR   P99090, DAAA_STAAN ;  Q6GFV1, DAAA_STAAR ;  Q6G8H7, DAAA_STAAS ;
DR   Q8NW24, DAAA_STAAW ;  Q5HNG0, DAAA_STAEQ ;  Q8CS41, DAAA_STAES ;
DR   P54694, DAAA_STAHA ;
//
ID   2.6.1.22
DE   (S)-3-amino-2-methylpropionate transaminase.
AN   (S)-3-amino-2-methylpropionate aminotransferase.
AN   Beta-aminobutyric transaminase.
AN   Beta-aminoisobutyrate-alpha-ketoglutarate transaminase.
AN   L-3-aminoisobutyrate aminotransferase.
AN   L-3-aminoisobutyrate transaminase.
AN   L-3-aminoisobutyric aminotransferase.
AN   L-AIBAT.
CA   (S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3-
CA   oxopropanoate + L-glutamate.
CC   -!- Also acts on beta-alanine and other omega-amino acids having carbon
CC       chains between 2 and 5.
CC   -!- The two enantiomers of the 2-methyl-3-oxopropanoate formed by the
CC       enzyme interconvert by enolization, so that this enzyme, together
CC       with EC 2.6.1.40, provide a route for interconversion of the
CC       enantiomers of 3-amino-2-methylpropanoate.
DR   P94427, GABT_BACSU ;  Q9BGI0, GABT_BOVIN ;  Q21217, GABT_CAEEL ;
DR   P22256, GABT_ECOLI ;  P80404, GABT_HUMAN ;  P61922, GABT_MOUSE ;
DR   P63505, GABT_MYCBO ;  P40829, GABT_MYCLE ;  P63504, GABT_MYCTU ;
DR   P80147, GABT_PIG   ;  P50554, GABT_RAT   ;
//
ID   2.6.1.23
DE   4-hydroxyglutamate transaminase.
AN   4-hydroxyglutamate aminotransferase.
CA   4-hydroxy-L-glutamate + 2-oxoglutarate = 4-hydroxy-2-oxoglutarate +
CA   L-glutamate.
CC   -!- Oxaloacetate can replace 2-oxoglutarate.
CC   -!- May be identical with EC 2.6.1.1.
//
ID   2.6.1.24
DE   Diiodotyrosine transaminase.
AN   Diiodotyrosine aminotransferase.
CA   3,5-diiodo-L-tyrosine + 2-oxoglutarate = 4-hydroxy-3,5-
CA   diiodophenylpyruvate + L-glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Also acts on 3,5-dichloro-, 3,5-dibromo- and 3-iodo-L-tyrosine,
CC       thyroxine and triiodothyronine.
CC   -!- Formerly EC 2.6.1.25.
//
ID   2.6.1.25
DE   Transferred entry: 2.6.1.24.
//
ID   2.6.1.26
DE   Thyroid-hormone transaminase.
AN   3,5-dinitrotyrosine aminotransferase.
AN   Thyroid-hormone aminotransferase.
CA   L-3,5,3'-triiodothyronine + 2-oxoglutarate = 3-(4-(4-hydroxy-3-
CA   iodophenoxy)-3,5-diiodophenyl)-2-oxopropanoate + L-glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Acts on monoiodotyrosine, diiodotyrosine, triiodothyronine, thyroxine
CC       and dinitrotyrosine (unlike EC 2.6.1.24, which does not act on
CC       dinitrotyrosine).
CC   -!- Pyruvate or oxaloacetate can act as acceptor.
//
ID   2.6.1.27
DE   Tryptophan transaminase.
AN   Tryptophan aminotransferase.
CA   L-tryptophan + 2-oxoglutarate = (indol-3-yl)pyruvate + L-glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Also acts on 5-hydroxytryptophan and, to a lesser extent, on the
CC       phenyl amino acids.
DR   Q9S7N2, TAA1_ARATH ;  Q9LR29, TAR1_ARATH ;  Q94A02, TAR2_ARATH ;
//
ID   2.6.1.28
DE   Tryptophan--phenylpyruvate transaminase.
AN   Tryptophan--phenylpyruvate aminotransferase.
CA   L-tryptophan + phenylpyruvate = (indol-3-yl)pyruvate + L-phenylalanine.
CC   -!- Valine, leucine and isoleucine can replace tryptophan as amino donor.
//
ID   2.6.1.29
DE   Diamine transaminase.
AN   Diamine aminotransferase.
CA   An alpha,omega-diamine + 2-oxoglutarate = an omega-aminoaldehyde +
CA   L-glutamate.
//
ID   2.6.1.30
DE   Pyridoxamine--pyruvate transaminase.
AN   Pyridoxamine--pyruvate aminotransferase.
AN   Pyridoxamine-pyruvic transaminase.
CA   Pyridoxamine + pyruvate = pyridoxal + L-alanine.
CF   Pyridoxal 5'-phosphate.
//
ID   2.6.1.31
DE   Pyridoxamine--oxaloacetate transaminase.
AN   Pyridoxamine--oxaloacetate aminotransferase.
CA   Pyridoxamine + oxaloacetate = pyridoxal + L-aspartate.
//
ID   2.6.1.32
DE   Valine--3-methyl-2-oxovalerate transaminase.
AN   Valine--3-methyl-2-oxovalerate aminotransferase.
AN   Valine--isoleucine aminotransferase.
AN   Valine--isoleucine transaminase.
CA   L-valine + (S)-3-methyl-2-oxopentanoate = 3-methyl-2-oxobutanoate +
CA   L-isoleucine.
//
ID   2.6.1.33
DE   dTDP-4-amino-4,6-dideoxy-D-glucose transaminase.
AN   dTDP-4-amino-4,6-dideoxy-D-glucose aminotransferase.
AN   TDP-4-keto-6-deoxy-D-glucose transaminase.
AN   Thymidine diphospho-4-keto-6-deoxy-D-glucose transaminase.
AN   Thymidine diphospho-4-keto-6-deoxy-D-glucose-glutamic transaminase.
CA   dTDP-4-amino-4,6-dideoxy-D-glucose + 2-oxoglutarate = dTDP-4-dehydro-6-
CA   deoxy-D-glucose + L-glutamate.
CF   Pyridoxal 5'-phosphate.
//
ID   2.6.1.34
DE   UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase.
AN   UDP-4-amino-2-acetamido-2,4,6-trideoxyglucose aminotransferase.
AN   UDP-4-amino-2-acetamido-2,4,6-trideoxyglucose transaminase.
CA   UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose + 2-oxoglutarate = UDP-2-
CA   acetamido-4-dehydro-2,6-dideoxyglucose + L-glutamate.
CF   Pyridoxal 5'-phosphate.
//
ID   2.6.1.35
DE   Glycine--oxaloacetate transaminase.
AN   Glycine--oxaloacetate aminotransferase.
CA   Glycine + oxaloacetate = glyoxylate + L-aspartate.
CF   Pyridoxal 5'-phosphate.
//
ID   2.6.1.36
DE   L-lysine 6-transaminase.
AN   L-lysine aminotransferase.
AN   L-lysine transaminase.
AN   Lysine epsilon-aminotransferase.
CA   L-lysine + 2-oxoglutarate = (S)-2-amino-6-oxohexanoate + L-glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- The product, (S)-2-amino-6-oxohexanoate, is converted into the
CC       intramolecularly dehydrated form, 1-piperideine 6-carboxylate.
DR   P63510, LAT_MYCBO  ;  P63509, LAT_MYCTU  ;  Q05174, LAT_NOCLA  ;
DR   Q01767, LAT_STRCL  ;
//
ID   2.6.1.37
DE   2-aminoethylphosphonate--pyruvate transaminase.
AN   (2-aminoethyl)phosphonate transaminase.
AN   (2-aminoethyl)phosphonate--pyruvate aminotransferase.
AN   (2-aminoethyl)phosphonic acid aminotransferase.
AN   2-aminoethylphosphonate aminotransferase.
AN   2-aminoethylphosphonate--pyruvate aminotransferase.
CA   (2-aminoethyl)phosphonate + pyruvate = 2-phosphonoacetaldehyde +
CA   L-alanine.
CF   Pyridoxal 5'-phosphate.
CC   -!- 2-aminoethylarsonate can replace 2-aminoethylphosphonate as a
CC       substrate.
DR   Q39AP8, PHNW1_BURS3;  Q13YI7, PHNW1_BURXL;  Q46UV8, PHNW1_CUPPJ;
DR   Q128B2, PHNW1_POLSJ;  Q39BS5, PHNW2_BURS3;  Q13P97, PHNW2_BURXL;
DR   Q46NS0, PHNW2_CUPPJ;  Q122G2, PHNW2_POLSJ;  A0KJL8, PHNW_AERHH ;
DR   C3P4E3, PHNW_BACAA ;  C3LAM8, PHNW_BACAC ;  A0RBE9, PHNW_BACAH ;
DR   Q81TE0, PHNW_BACAN ;  B7JFQ9, PHNW_BACC0 ;  Q73BH8, PHNW_BACC1 ;
DR   B7IN19, PHNW_BACC2 ;  C1EM34, PHNW_BACC3 ;  B7HH81, PHNW_BACC4 ;
DR   B7HK48, PHNW_BACC7 ;  Q8RLU1, PHNW_BACCE ;  A7GMM0, PHNW_BACCN ;
DR   B9IUR6, PHNW_BACCQ ;  Q81G81, PHNW_BACCR ;  Q63E45, PHNW_BACCZ ;
DR   Q5L9Q0, PHNW_BACFN ;  Q64PZ3, PHNW_BACFR ;  Q6HLM0, PHNW_BACHK ;
DR   A6L4N0, PHNW_BACV8 ;  A9VKQ3, PHNW_BACWK ;  B1Z0T3, PHNW_BURA4 ;
DR   Q1BQZ3, PHNW_BURCA ;  A3MCV7, PHNW_BURM7 ;  A2S233, PHNW_BURM9 ;
DR   Q62CM5, PHNW_BURMA ;  A1UZE5, PHNW_BURMS ;  A3P2G7, PHNW_BURP0 ;
DR   Q3JH97, PHNW_BURP1 ;  A3NGW6, PHNW_BURP6 ;  B2JLS3, PHNW_BURP8 ;
DR   Q63NF6, PHNW_BURPS ;  Q2T3K6, PHNW_BURTA ;  Q0JZT9, PHNW_CUPNH ;
DR   B3RBH4, PHNW_CUPTR ;  Q2SHM3, PHNW_HAHCH ;  A6TFW2, PHNW_KLEP7 ;
DR   Q88YN9, PHNW_LACPL ;  B1HPR6, PHNW_LYSSC ;  Q02JF1, PHNW_PSEAB ;
DR   Q9I434, PHNW_PSEAE ;  Q1I7U0, PHNW_PSEE4 ;  Q4K9L8, PHNW_PSEF5 ;
DR   A5W695, PHNW_PSEP1 ;  Q3K9Y3, PHNW_PSEPF ;  B0KIG1, PHNW_PSEPG ;
DR   Q88KT0, PHNW_PSEPK ;  Q8RSQ4, PHNW_PSEPU ;  B1JBM5, PHNW_PSEPW ;
DR   A1SY89, PHNW_PSYIN ;  Q92UV9, PHNW_RHIME ;  B5EXH1, PHNW_SALA4 ;
DR   Q57SD3, PHNW_SALCH ;  B5FKT6, PHNW_SALDC ;  B5QTH9, PHNW_SALEP ;
DR   B5R6T2, PHNW_SALG2 ;  B4T9C6, PHNW_SALHS ;  B4SWS3, PHNW_SALNS ;
DR   Q5PFR0, PHNW_SALPA ;  A9MWZ9, PHNW_SALPB ;  C0Q7V5, PHNW_SALPC ;
DR   B5BDA1, PHNW_SALPK ;  B4TMB1, PHNW_SALSV ;  Q8Z8W6, PHNW_SALTI ;
DR   P96060, PHNW_SALTY ;  A0LMC0, PHNW_SYNFM ;  A5F049, PHNW_VIBC3 ;
DR   Q9KLY7, PHNW_VIBCH ;  C3LVL9, PHNW_VIBCM ;  Q87JL4, PHNW_VIBPA ;
DR   Q8D3M4, PHNW_VIBVU ;  Q7MF44, PHNW_VIBVY ;  Q183T0, PHNXW_CLOD6;
//
ID   2.6.1.38
DE   Histidine transaminase.
AN   Histidine aminotransferase.
CA   L-histidine + 2-oxoglutarate = (imidazol-5-yl)pyruvate + L-glutamate.
//
ID   2.6.1.39
DE   2-aminoadipate transaminase.
AN   2-aminoadipate aminotransferase.
CA   L-2-aminoadipate + 2-oxoglutarate = 2-oxoadipate + L-glutamate.
CF   Pyridoxal 5'-phosphate.
DR   Q5E9N4, AADAT_BOVIN;  Q8N5Z0, AADAT_HUMAN;  Q9WVM8, AADAT_MOUSE;
DR   Q64602, AADAT_RAT  ;  Q72LL6, LYSN_THET2 ;
//
ID   2.6.1.40
DE   (R)-3-amino-2-methylpropionate--pyruvate transaminase.
AN   (R)-3-amino-2-methylpropionate transaminase.
AN   (R)-3-amino-2-methylpropionate--pyruvate aminotransferase.
AN   Beta-aminoisobutyrate--pyruvate aminotransferase.
AN   Beta-aminoisobutyrate--pyruvate transaminase.
AN   Beta-aminoisobutyrate-pyruvate aminotransferase.
AN   D-3-aminoisobutyrate--pyruvate transaminase.
AN   D-3-aminoisobutyrate-pyruvate aminotransferase.
AN   D-3-aminoisobutyrate-pyruvate transaminase.
AN   D-AIBAT.
AN   D-beta-aminoisobutyrate:pyruvate aminotransferase.
CA   (R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate +
CA   L-alanine.
CC   -!- The two enantiomers of the 2-methyl-3-oxopropanoate formed by the
CC       enzyme interconvert by enolization, so that this enzyme, together
CC       with EC 2.6.1.22, provide a route for interconversion of the
CC       enantiomers of 3-amino-2-methylpropanoate.
CC   -!- Formerly EC 2.6.1.61.
DR   Q17QF0, AGT2_BOVIN ;  Q9BYV1, AGT2_HUMAN ;  Q3UEG6, AGT2_MOUSE ;
DR   Q5RFA3, AGT2_PONAB ;  Q64565, AGT2_RAT   ;
//
ID   2.6.1.41
DE   D-methionine--pyruvate transaminase.
AN   D-methionine aminotransferase.
AN   D-methionine--pyruvate aminotransferase.
CA   D-methionine + pyruvate = 4-methylthio-2-oxobutanoate + L-alanine.
CC   -!- Oxaloacetate can replace pyruvate.
//
ID   2.6.1.42
DE   Branched-chain-amino-acid transaminase.
AN   Branched-chain amino acid aminotransferase.
AN   Transaminase B.
CA   (1) L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.
CA   (2) 2-oxoglutaric acid + L-isoleucine = (S)-3-methyl-2-oxopentanoic acid
CA   + L-glutamic acid.
CA   (3) 2-oxoglutaric acid + L-valine = 3-methyl-2-oxobutanoic acid +
CA   L-glutamic acid.
CF   Pyridoxal 5'-phosphate.
CC   -!- Also acts on L-isoleucine and L-valine.
CC   -!- Different from EC 2.6.1.66.
PR   PROSITE; PDOC00618;
DR   O14370, BCA1_SCHPO ;  P38891, BCA1_YEAST ;  P47176, BCA2_YEAST ;
DR   Q93Y32, BCAT1_ARATH;  P54687, BCAT1_HUMAN;  P24288, BCAT1_MOUSE;
DR   P54690, BCAT1_RAT  ;  Q9GKM4, BCAT1_SHEEP;  Q9M439, BCAT2_ARATH;
DR   Q5EA40, BCAT2_BOVIN;  O15382, BCAT2_HUMAN;  O35855, BCAT2_MOUSE;
DR   O19098, BCAT2_PIG  ;  Q5REP0, BCAT2_PONAB;  O35854, BCAT2_RAT  ;
DR   Q9M401, BCAT3_ARATH;  Q9FYA6, BCAT5_ARATH;  Q9LPM9, BCAT6_ARATH;
DR   P54688, BCAT_CAEEL ;  Q54N47, BCAT_DICDI ;  A9UZ24, BCAT_MONBE ;
DR   A7SLW1, BCAT_NEMVE ;  O31461, ILVE1_BACSU;  P39576, ILVE2_BACSU;
DR   O67733, ILVE_AQUAE ;  O29329, ILVE_ARCFU ;  P0AB82, ILVE_ECO57 ;
DR   P0AB81, ILVE_ECOL6 ;  P0AB80, ILVE_ECOLI ;  P54689, ILVE_HAEIN ;
DR   Q9ZJF1, ILVE_HELPJ ;  O26004, ILVE_HELPY ;  Q58414, ILVE_METJA ;
DR   O27481, ILVE_METTH ;  O32954, ILVE_MYCLE ;  A0R066, ILVE_MYCS2 ;
DR   Q10399, ILVE_MYCTU ;  O86428, ILVE_PSEAE ;  Q1RIJ2, ILVE_RICBR ;
DR   Q92I26, ILVE_RICCN ;  Q4ULR3, ILVE_RICFE ;  O05970, ILVE_RICPR ;
DR   Q9AKE5, ILVE_RICTY ;  P0A1A6, ILVE_SALTI ;  P0A1A5, ILVE_SALTY ;
DR   Q5HIC1, ILVE_STAAC ;  P63512, ILVE_STAAM ;  P99138, ILVE_STAAN ;
DR   Q6GJB4, ILVE_STAAR ;  Q6GBT3, ILVE_STAAS ;  P63513, ILVE_STAAW ;
DR   Q5HRJ8, ILVE_STAEQ ;  Q8CQ78, ILVE_STAES ;  O86505, ILVE_STRCO ;
DR   P54691, ILVE_SYNY3 ;  P74921, ILVE_THEMA ;  Q9Y885, TOXF_COCCA ;
//
ID   2.6.1.43
DE   Aminolevulinate transaminase.
AN   Aminolevulinate aminotransferase.
CA   5-aminolevulinate + pyruvate = 4,5-dioxopentanoate + L-alanine.
CF   Pyridoxal 5'-phosphate.
//
ID   2.6.1.44
DE   Alanine--glyoxylate transaminase.
AN   AGT.
AN   Alanine--glyoxylate aminotransferase.
CA   L-alanine + glyoxylate = pyruvate + glycine.
CF   Pyridoxal 5'-phosphate.
CC   -!- With one component of the animal enzyme, 2-oxobutanoate can replace
CC       glyoxylate.
CC   -!- A second component also catalyzes the reaction of EC 2.6.1.51.
PR   PROSITE; PDOC00514;
DR   Q940M2, AGT21_ARATH;  Q94AL9, AGT22_ARATH;  Q9SR86, AGT23_ARATH;
DR   Q17QF0, AGT2_BOVIN ;  Q9BYV1, AGT2_HUMAN ;  Q3UEG6, AGT2_MOUSE ;
DR   Q5RFA3, AGT2_PONAB ;  Q64565, AGT2_RAT   ;  P43567, AGX1_YEAST ;
DR   Q56YA5, SGAT_ARATH ;  P84187, SGAT_MAIZE ;  P84188, SGAT_WHEAT ;
DR   P31029, SPYA_CALJA ;  Q54GT6, SPYA_DICDI ;  P41689, SPYA_FELCA ;
DR   P21549, SPYA_HUMAN ;  O35423, SPYA_MOUSE ;  Q5RDP0, SPYA_PONAB ;
DR   P31030, SPYA_RABIT ;  P09139, SPYA_RAT   ;
//
ID   2.6.1.45
DE   Serine--glyoxylate transaminase.
AN   Serine--glyoxylate aminotransferase.
AN   SGAT.
CA   L-serine + glyoxylate = 3-hydroxypyruvate + glycine.
CF   Pyridoxal 5'-phosphate.
PR   PROSITE; PDOC00514;
DR   O08374, SGAA_HYPME ;  P55819, SGAA_METEA ;  Q56YA5, SGAT_ARATH ;
DR   P84187, SGAT_MAIZE ;  P84188, SGAT_WHEAT ;
//
ID   2.6.1.46
DE   Diaminobutyrate--pyruvate transaminase.
AN   Diaminobutyrate--pyruvate aminotransferase.
AN   L-diaminobutyric acid transaminase.
CA   L-2,4-diaminobutanoate + pyruvate = L-aspartate 4-semialdehyde +
CA   L-alanine.
CF   Pyridoxal 5'-phosphate.
//
ID   2.6.1.47
DE   Alanine--oxomalonate transaminase.
AN   Alanine--oxomalonate aminotransferase.
AN   L-alanine-ketomalonate transaminase.
CA   L-alanine + oxomalonate = pyruvate + aminomalonate.
CF   Pyridoxal 5'-phosphate.
//
ID   2.6.1.48
DE   5-aminovalerate transaminase.
AN   5-aminovalerate aminotransferase.
AN   Delta-aminovalerate aminotransferase.
AN   Delta-aminovalerate transaminase.
CA   5-aminopentanoate + 2-oxoglutarate = 5-oxopentanoate + L-glutamate.
CF   Pyridoxal 5'-phosphate.
//
ID   2.6.1.49
DE   Dihydroxyphenylalanine transaminase.
AN   Dihydroxyphenylalanine aminotransferase.
AN   DOPA aminotransferase.
CA   3,4-dihydroxy-L-phenylalanine + 2-oxoglutarate = 3,4-
CA   dihydroxyphenylpyruvate + L-glutamate.
CF   Pyridoxal 5'-phosphate.
//
ID   2.6.1.50
DE   Glutamine--scyllo-inositol transaminase.
AN   Glutamine--scyllo-inosose aminotransferase.
AN   Glutamine--scyllo-inosose transaminase.
CA   L-glutamine + 2,4,6/3,5-pentahydroxycyclohexanone = 2-oxoglutaramate +
CA   1-amino-1-deoxy-scyllo-inositol.
CF   Pyridoxal 5'-phosphate.
DR   P77952, GLSA_STRGR ;
//
ID   2.6.1.51
DE   Serine--pyruvate transaminase.
AN   Serine--pyruvate aminotransferase.
CA   L-serine + pyruvate = 3-hydroxypyruvate + L-alanine.
CF   Pyridoxal 5'-phosphate.
CC   -!- The liver enzyme may be identical with EC 2.6.1.44.
PR   PROSITE; PDOC00514;
DR   Q56YA5, SGAT_ARATH ;  P31029, SPYA_CALJA ;  Q54GT6, SPYA_DICDI ;
DR   P41689, SPYA_FELCA ;  P21549, SPYA_HUMAN ;  O35423, SPYA_MOUSE ;
DR   Q5RDP0, SPYA_PONAB ;  P31030, SPYA_RABIT ;  P09139, SPYA_RAT   ;
//
ID   2.6.1.52
DE   Phosphoserine transaminase.
AN   3-phosphoserine aminotransferase.
AN   3PHP transaminase.
AN   Hydroxypyruvic phosphate--glutamic transaminase.
AN   L-phosphoserine aminotransferase.
AN   Phosphohydroxypyruvate transaminase.
AN   Phosphohydroxypyruvic--glutamic transaminase.
AN   Phosphoserine aminotransferase.
AN   PSAT.
CA   (1) O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate +
CA   L-glutamate.
CA   (2) 4-phosphonooxy-L-threonine + 2-oxoglutarate = (3R)-3-hydroxy-2-oxo-4-
CA   phosphonooxybutanoate + L-glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Catalyzes the second step in the phosphorylated pathway of serine
CC       biosynthesis in Escherichia coli.
CC   -!- Also catalyzes the third step in the biosynthesis of the coenzyme
CC       pyridoxal 5'-phosphate in E.coli (using reaction 2 above).
CC   -!- In E.coli, pyridoxal 5'-phosphate is synthesized de novo by a pathway
CC       that involves EC 1.2.1.72, EC 1.1.1.290, EC 2.6.1.52, EC 1.1.1.262,
CC       EC 2.6.99.2 and EC 1.4.3.5 (with pyridoxine 5'-phosphate as
CC       substrate).
CC   -!- Pyridoxal phosphate is the cofactor for both activities and therefore
CC       seems to be involved in its own biosynthesis.
CC   -!- Non-phosphorylated forms of serine and threonine are not substrates.
PR   PROSITE; PDOC00514;
DR   A1TSA3, SERC_ACIAC ;  Q6F961, SERC_ACIAD ;  B7GY87, SERC_ACIB3 ;
DR   B7I5D6, SERC_ACIB5 ;  B2HWW3, SERC_ACIBC ;  A3M7Z0, SERC_ACIBT ;
DR   B7J6V1, SERC_ACIF2 ;  B5EPR5, SERC_ACIF5 ;  Q96255, SERC_ARATH ;
DR   Q5P7U7, SERC_AROAE ;  B6YQL2, SERC_AZOPC ;  C1DRQ9, SERC_AZOVD ;
DR   C3P210, SERC_BACAA ;  Q9RME2, SERC_BACAO ;  Q734W9, SERC_BACC1 ;
DR   Q59196, SERC_BACCI ;  Q81BC0, SERC_BACCR ;  Q638W1, SERC_BACCZ ;
DR   Q5LDN9, SERC_BACFN ;  Q64UR4, SERC_BACFR ;  Q9KDM4, SERC_BACHD ;
DR   Q6HGI0, SERC_BACHK ;  Q5WHT9, SERC_BACSK ;  P80862, SERC_BACSU ;
DR   Q8A8L4, SERC_BACTN ;  A6L5A6, SERC_BACV8 ;  Q1LTL2, SERC_BAUCH ;
DR   Q7VR40, SERC_BLOFL ;  Q492S5, SERC_BLOPB ;  Q2L2T1, SERC_BORA1 ;
DR   Q7WGU2, SERC_BORBR ;  Q7W5Z9, SERC_BORPA ;  A9IJI3, SERC_BORPD ;
DR   Q7VZG4, SERC_BORPE ;  B8D9A2, SERC_BUCA5 ;  P57397, SERC_BUCAI ;
DR   P81435, SERC_BUCAP ;  B8D7K4, SERC_BUCAT ;  P59492, SERC_BUCBP ;
DR   Q057N5, SERC_BUCCC ;  B1YV30, SERC_BURA4 ;  Q1BY31, SERC_BURCA ;
DR   B1JXR6, SERC_BURCC ;  A0K5L8, SERC_BURCH ;  B4EB45, SERC_BURCJ ;
DR   Q0BH96, SERC_BURCM ;  A9ADV9, SERC_BURM1 ;  B2JF00, SERC_BURP8 ;
DR   B2T637, SERC_BURPP ;  Q39IG4, SERC_BURS3 ;  A4JCH1, SERC_BURVG ;
DR   P91856, SERC_CAEEL ;  A8FKB5, SERC_CAMJ8 ;  A7H543, SERC_CAMJD ;
DR   Q9PIH3, SERC_CAMJE ;  A1VY45, SERC_CAMJJ ;  Q5HWE5, SERC_CAMJR ;
DR   B9KDM7, SERC_CAMLR ;  Q7NVP1, SERC_CHRVO ;  A8AIH6, SERC_CITK8 ;
DR   A4QCG9, SERC_CORGB ;  B6J893, SERC_COXB1 ;  B6J1E0, SERC_COXB2 ;
DR   A9KCT6, SERC_COXBN ;  A9NC17, SERC_COXBR ;  Q83E12, SERC_COXBU ;
DR   A9BM04, SERC_DELAS ;  B8FLC3, SERC_DESAA ;  A9A0A5, SERC_DESOH ;
DR   Q6ALW3, SERC_DESPS ;  Q55CQ6, SERC_DICDI ;  A5EV80, SERC_DICNV ;
DR   Q9VAN0, SERC_DROME ;  A7ZJZ6, SERC_ECO24 ;  B7UMZ3, SERC_ECO27 ;
DR   B7MHL6, SERC_ECO45 ;  B7LD99, SERC_ECO55 ;  Q8XEA7, SERC_ECO57 ;
DR   B5YT41, SERC_ECO5E ;  B7NM68, SERC_ECO7I ;  B7MS22, SERC_ECO81 ;
DR   B7M835, SERC_ECO8A ;  C4ZQ33, SERC_ECOBW ;  B1X847, SERC_ECODH ;
DR   A7ZYL0, SERC_ECOHS ;  A1A9I4, SERC_ECOK1 ;  Q0TJE6, SERC_ECOL5 ;
DR   Q8FJB7, SERC_ECOL6 ;  B1IW24, SERC_ECOLC ;  P23721, SERC_ECOLI ;
DR   B7NAQ6, SERC_ECOLU ;  B6I8X9, SERC_ECOSE ;  B1LJV7, SERC_ECOSM ;
DR   Q1RDV1, SERC_ECOUT ;  Q9X4H1, SERC_EDWI9 ;  A4W8S7, SERC_ENT38 ;
DR   A7MES8, SERC_ENTS8 ;  Q6D400, SERC_ERWCT ;  B2VC80, SERC_ERWT9 ;
DR   B7LN70, SERC_ESCF3 ;  C4L432, SERC_EXISA ;  A5FH28, SERC_FLAJ1 ;
DR   A6GXC2, SERC_FLAPJ ;  Q5L296, SERC_GEOKA ;  Q7VLP0, SERC_HAEDU ;
DR   P44336, SERC_HAEIN ;  Q0I322, SERC_HAES1 ;  Q2SCF2, SERC_HAHCH ;
DR   C4K3B1, SERC_HAMD5 ;  A9B6Q3, SERC_HERA2 ;  A4G865, SERC_HERAR ;
DR   Q9Y617, SERC_HUMAN ;  Q5QZ48, SERC_IDILO ;  A6T1G7, SERC_JANMA ;
DR   B5XY88, SERC_KLEP3 ;  A6T700, SERC_KLEP7 ;  B2GBS2, SERC_LACF3 ;
DR   A8YW78, SERC_LACH4 ;  Q9CHW5, SERC_LACLA ;  A2RIS2, SERC_LACLM ;
DR   Q031D5, SERC_LACLS ;  Q88ZU5, SERC_LACPL ;  C1D8N3, SERC_LARHH ;
DR   Q5X5E7, SERC_LEGPA ;  A5IBR0, SERC_LEGPC ;  Q5ZVM2, SERC_LEGPH ;
DR   Q5WWT0, SERC_LEGPL ;  B0SCE2, SERC_LEPBA ;  B0SKW4, SERC_LEPBP ;
DR   Q72VI2, SERC_LEPIC ;  Q8F930, SERC_LEPIN ;  Q03W65, SERC_LEUMM ;
DR   Q926T3, SERC_LISIN ;  Q71VT6, SERC_LISMF ;  Q8Y3L0, SERC_LISMO ;
DR   B1HSU6, SERC_LYSSC ;  Q65S80, SERC_MANSM ;  A6VZ92, SERC_MARMS ;
DR   Q8TNI1, SERC_METAC ;  P52878, SERC_METBF ;  Q8PT12, SERC_METMA ;
DR   Q99K85, SERC_MOUSE ;  A0QBI3, SERC_MYCA1 ;  P63515, SERC_MYCBO ;
DR   O33062, SERC_MYCLE ;  Q742L2, SERC_MYCPA ;  A3Q635, SERC_MYCSJ ;
DR   A1ULN4, SERC_MYCSK ;  Q1B3G6, SERC_MYCSS ;  P63514, SERC_MYCTU ;
DR   A1TF55, SERC_MYCVP ;  Q1D2L9, SERC_MYXXD ;  Q5F7A0, SERC_NEIG1 ;
DR   O34370, SERC_NEIMA ;  P57007, SERC_NEIMB ;  A1KV48, SERC_NEIMF ;
DR   Q820S0, SERC_NITEU ;  A1SEM0, SERC_NOCSJ ;  A6L9B7, SERC_PARD8 ;
DR   P57881, SERC_PASMU ;  C6DF64, SERC_PECCP ;  Q7N6D6, SERC_PHOLL ;
DR   Q6LPD9, SERC_PHOPR ;  A1VR16, SERC_POLNA ;  Q12CL3, SERC_POLSJ ;
DR   B2RID6, SERC_PORG3 ;  Q7MV30, SERC_PORGI ;  B4ET24, SERC_PROMH ;
DR   A6V2Q8, SERC_PSEA7 ;  B7V9J9, SERC_PSEA8 ;  Q02PX3, SERC_PSEAB ;
DR   Q9HZ66, SERC_PSEAE ;  Q1IDA2, SERC_PSEE4 ;  C3K6J5, SERC_PSEFS ;
DR   Q3ILA3, SERC_PSEHT ;  A4XTE7, SERC_PSEMY ;  Q88M07, SERC_PSEPK ;
DR   Q885T5, SERC_PSESM ;  Q9RI02, SERC_PSEST ;  Q4ZQ94, SERC_PSEU2 ;
DR   P10658, SERC_RABIT ;  B2U882, SERC_RALPJ ;  Q8Y0Z0, SERC_RALSO ;
DR   Q7UQL3, SERC_RHOBA ;  Q21Y51, SERC_RHOFD ;  C1ATN6, SERC_RHOOB ;
DR   Q0S6R3, SERC_RHOSR ;  A1AWS0, SERC_RUTMC ;  B5F159, SERC_SALA4 ;
DR   A9MHX6, SERC_SALAR ;  Q57R24, SERC_SALCH ;  B5FQ49, SERC_SALDC ;
DR   B5QYQ7, SERC_SALEP ;  B5R8J4, SERC_SALG2 ;  P62676, SERC_SALGL ;
DR   B4TD37, SERC_SALHS ;  B4T141, SERC_SALNS ;  A9N7V7, SERC_SALPB ;
DR   C0PXU3, SERC_SALPC ;  B4TRT8, SERC_SALSV ;  P62677, SERC_SALTI ;
DR   P55900, SERC_SALTY ;  Q10349, SERC_SCHPO ;  A8GCH0, SERC_SERP5 ;
DR   A1S6D1, SERC_SHEAM ;  B8EA90, SERC_SHEB2 ;  A3D4A1, SERC_SHEB5 ;
DR   A6WNN5, SERC_SHEB8 ;  A9L2Y2, SERC_SHEB9 ;  Q12MU6, SERC_SHEDO ;
DR   Q081U0, SERC_SHEFN ;  B0TT41, SERC_SHEHH ;  Q8EEH2, SERC_SHEON ;
DR   A8H4A2, SERC_SHEPA ;  A4Y757, SERC_SHEPC ;  B8CMG9, SERC_SHEPW ;
DR   A0KWN5, SERC_SHESA ;  A8FVN8, SERC_SHESH ;  Q0HIX3, SERC_SHESM ;
DR   Q0HV09, SERC_SHESR ;  A1RJD3, SERC_SHESW ;  B1KF45, SERC_SHEWM ;
DR   B2TUH4, SERC_SHIB3 ;  Q31YU4, SERC_SHIBS ;  Q32E24, SERC_SHIDS ;
DR   Q83LP3, SERC_SHIFL ;  Q3Z3L5, SERC_SHISS ;  Q2NUB0, SERC_SODGM ;
DR   P52877, SERC_SPIOL ;  Q8E3Y3, SERC_STRA3 ;  B4SP45, SERC_STRM5 ;
DR   B2FKF0, SERC_STRMK ;  Q8DSV3, SERC_STRMU ;  A4W0D4, SERC_STRS2 ;
DR   A3CPJ2, SERC_STRSV ;  A4VU42, SERC_STRSY ;  Q5LYP0, SERC_STRT1 ;
DR   Q5M3A4, SERC_STRT2 ;  Q03JH6, SERC_STRTD ;  B9DTW4, SERC_STRU0 ;
DR   A0LK14, SERC_SYNFM ;  Q3SK88, SERC_THIDA ;  A5CWI0, SERC_VESOH ;
DR   Q9KSU7, SERC_VIBCH ;  Q5E6F2, SERC_VIBF1 ;  B5FCJ8, SERC_VIBFM ;
DR   Q87QA3, SERC_VIBPA ;  Q8D900, SERC_VIBVU ;  Q7MLH6, SERC_VIBVY ;
DR   Q8D268, SERC_WIGBR ;  Q8PLY7, SERC_XANAC ;  Q3BUZ3, SERC_XANC5 ;
DR   Q4UTC9, SERC_XANC8 ;  B0RUW3, SERC_XANCB ;  Q8PA97, SERC_XANCP ;
DR   Q2P354, SERC_XANOM ;  B2SJJ1, SERC_XANOP ;  Q5H079, SERC_XANOR ;
DR   Q8RLW0, SERC_XENNA ;  Q9PB19, SERC_XYLFA ;  Q87BU0, SERC_XYLFT ;
DR   P33330, SERC_YEAST ;  P19689, SERC_YERE8 ;  A7FJX0, SERC_YERP3 ;
DR   Q1CA74, SERC_YERPA ;  B2KA22, SERC_YERPB ;  Q8ZGB4, SERC_YERPE ;
DR   A9R7I1, SERC_YERPG ;  A4TN19, SERC_YERPP ;  Q66CI9, SERC_YERPS ;
DR   B1JRE0, SERC_YERPY ;
//
ID   2.6.1.53
DE   Transferred entry: 1.4.1.13.
//
ID   2.6.1.54
DE   Pyridoxamine-phosphate transaminase.
AN   Pyridoxamine-phosphate aminotransferase.
CA   Pyridoxamine 5'-phosphate + 2-oxoglutarate = pyridoxal 5'-phosphate +
CA   D-glutamate.
CC   -!- Also acts, more slowly, on pyridoxamine.
//
ID   2.6.1.55
DE   Taurine--2-oxoglutarate transaminase.
AN   Taurine aminotransferase.
AN   Taurine transaminase.
AN   Taurine--alpha-ketoglutarate aminotransferase.
AN   Taurine--glutamate transaminase.
CA   Taurine + 2-oxoglutarate = sulfoacetaldehyde + L-glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Also acts on D,L-3-amino-isobutanoate, beta-alanine and
CC       3-aminopropanesulfonate.
CC   -!- Involved in the microbial utilization of beta-alanine.
//
ID   2.6.1.56
DE   1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase.
AN   1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol aminotransferase.
CA   1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol + pyruvate = 1D-1-
CA   guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-alanine.
CC   -!- L-glutamate and L-glutamine can also act as amino donors.
//
ID   2.6.1.57
DE   Aromatic-amino-acid transaminase.
CA   An aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid +
CA   L-glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- L-methionine can also act as donor, more slowly.
CC   -!- Oxaloacetate can act as acceptor.
CC   -!- Controlled proteolysis converts the enzyme to EC 2.6.1.1.
PR   PROSITE; PDOC00098;
DR   Q86AG8, AATR1_DICDI;  O14192, AATR1_SCHPO;  Q54K00, AATR2_DICDI;
DR   O94570, AATR2_SCHPO;  Q9Y7S6, AATR3_SCHPO;  P53090, ARO8_YEAST ;
DR   P38840, ARO9_YEAST ;  P43336, PHHC_PSEAE ;  P04693, TYRB_ECOLI ;
DR   O85746, TYRB_KLEPN ;  P95468, TYRB_PARDE ;  P74861, TYRB_SALTY ;
//
ID   2.6.1.58
DE   Phenylalanine(histidine) transaminase.
AN   Phenylalanine(histidine) aminotransferase.
CA   L-phenylalanine + pyruvate = phenylpyruvate + L-alanine.
CC   -!- L-histidine and L-tyrosine can act instead of L-phenylalanine; in the
CC       reverse reaction, L-methionine, L-serine and L-glutamine can replace
CC       L-alanine.
//
ID   2.6.1.59
DE   dTDP-4-amino-4,6-dideoxygalactose transaminase.
AN   dTDP-4-amino-4,6-dideoxygalactose aminotransferase.
CA   dTDP-4-amino-4,6-dideoxy-D-galactose + 2-oxoglutarate = dTDP-4-dehydro-6-
CA   deoxy-D-galactose + L-glutamate.
CF   Pyridoxal 5'-phosphate.
//
ID   2.6.1.60
DE   Aromatic-amino-acid--glyoxylate transaminase.
AN   Aromatic-amino-acid--glyoxylate aminotransferase.
CA   An aromatic amino acid + glyoxylate = an aromatic oxo acid + glycine.
CC   -!- Phenylalanine, kynurenine, tyrosine and histidine can act as amino
CC       donors.
CC   -!- Glyoxylate, pyruvate and hydroxypyruvate can act as amino acceptors.
//
ID   2.6.1.61
DE   Transferred entry: 2.6.1.40.
//
ID   2.6.1.62
DE   Adenosylmethionine--8-amino-7-oxononanoate transaminase.
AN   7,8-diamino-pelargonic acid aminotransferase.
AN   7,8-diaminononanoate aminotransferase.
AN   Adenosylmethionine--8-amino-7-oxononanoate aminotransferase.
AN   DAPA aminotransferase.
CA   S-adenosyl-L-methionine + 8-amino-7-oxononanoate = S-adenosyl-4-
CA   methylthio-2-oxobutanoate + 7,8-diaminononanoate.
CF   Pyridoxal 5'-phosphate.
CC   -!- S-adenosylhomocysteine can also act as donor.
PR   PROSITE; PDOC00519;
DR   E1WTS4, BIOAB_BACF6;  Q5LEY1, BIOAB_BACFN;  Q64VX4, BIOAB_BACFR;
DR   E6SRG2, BIOAB_BACT6;  Q8A7T2, BIOAB_BACTN;  B7GHM5, BIOA_ANOFW ;
DR   O66557, BIOA_AQUAE ;  P57379, BIOA_BUCAI ;  Q8K9P0, BIOA_BUCAP ;
DR   Q89AK4, BIOA_BUCBP ;  P13071, BIOA_CITFR ;  P46395, BIOA_CORGL ;
DR   Q728P4, BIOA_DESVH ;  P12995, BIOA_ECOLI ;  P53656, BIOA_ESCVU ;
DR   Q74CT9, BIOA_GEOSL ;  P44426, BIOA_HAEIN ;  Q9ZKM5, BIOA_HELPJ ;
DR   O25627, BIOA_HELPY ;  P22805, BIOA_LYSSH ;  Q58696, BIOA_METJA ;
DR   P0A4X7, BIOA_MYCBO ;  P45488, BIOA_MYCLE ;  P0A4X6, BIOA_MYCTU ;
DR   P12677, BIOA_SALTY ;  P36568, BIOA_SERMA ;  Q2FVJ6, BIOA_STAA8 ;
DR   Q9FCC2, BIOA_STRCO ;  P50277, BIOA_YEAST ;
//
ID   2.6.1.63
DE   Kynurenine--glyoxylate transaminase.
AN   Kynurenine--glyoxylate aminotransferase.
CA   L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate +
CA   glycine.
CC   -!- Acts, more slowly, on L-phenylalanine, L-histidine and L-tyrosine.
DR   Q0P5G4, KAT3_BOVIN ;  Q7T3E5, KAT3_DANRE ;  Q6YP21, KAT3_HUMAN ;
DR   Q71RI9, KAT3_MOUSE ;  Q58FK9, KAT3_RAT   ;
//
ID   2.6.1.64
DE   Glutamine--phenylpyruvate transaminase.
AN   Glutamine transaminase K.
AN   Glutamine--phenylpyruvate aminotransferase.
CA   L-glutamine + phenylpyruvate = 2-oxoglutaramate + L-phenylalanine.
CF   Pyridoxal 5'-phosphate.
CC   -!- L-methionine, L-histidine and L-tyrosine can act as donors.
CC   -!- Has little activity on pyruvate and glyoxylate (cf. EC 2.6.1.15).
DR   Q16773, KAT1_HUMAN ;  Q8BTY1, KAT1_MOUSE ;  Q08415, KAT1_RAT   ;
DR   Q54KM6, KAT_DICDI  ;
//
ID   2.6.1.65
DE   N(6)-acetyl-beta-lysine transaminase.
AN   N(6)-acetyl-beta-lysine aminotransferase.
CA   6-acetamido-3-aminohexanoate + 2-oxoglutarate = 6-acetamido-3-
CA   oxohexanoate + L-glutamate.
CF   Pyridoxal 5'-phosphate.
//
ID   2.6.1.66
DE   Valine--pyruvate transaminase.
AN   Alanine--valine transaminase.
AN   Transaminase C.
AN   Valine--pyruvate aminotransferase.
CA   L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine.
CF   Pyridoxal 5'-phosphate.
CC   -!- Different from EC 2.6.1.42.
DR   P09053, AVTA_ECOLI ;
//
ID   2.6.1.67
DE   2-aminohexanoate transaminase.
AN   2-aminohexanoate aminotransferase.
AN   Norleucine aminotransferase.
AN   Norleucine transaminase.
CA   L-2-aminohexanoate + 2-oxoglutarate = 2-oxohexanoate + L-glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Also acts on L-leucine and, more slowly, on L-isoleucine, L-2-
CC       aminopentanoate and L-aspartate.
//
ID   2.6.1.68
DE   Ornithine(lysine) transaminase.
AN   Ornithine(lysine) aminotransferase.
CA   L-ornithine + 2-oxoglutarate = 3,4-dihydro-2H-pyrrole-2-carboxylate +
CA   L-glutamate + H(2)O.
CC   -!- The enzyme from Trichomonas vaginalis also acts on L-lysine,
CC       producing 2,3,4,5-tetrahydropyridine-2-carboxylate.
//
ID   2.6.1.69
DE   Deleted entry.
//
ID   2.6.1.70
DE   Aspartate--phenylpyruvate transaminase.
AN   Aspartate--phenylpyruvate aminotransferase.
CA   L-aspartate + phenylpyruvate = oxaloacetate + L-phenylalanine.
CC   -!- The enzyme from Pseudomonas putida also acts on
CC       4-hydroxyphenylpyruvate and, more slowly, on L-glutamate and
CC       L-histidine.
//
ID   2.6.1.71
DE   Lysine--pyruvate 6-transaminase.
AN   Lysine--pyruvate 6-aminotransferase.
CA   L-lysine + pyruvate = (S)-2-amino-6-oxohexanoate + L-alanine.
//
ID   2.6.1.72
DE   D-4-hydroxyphenylglycine transaminase.
AN   D-4-hydroxyphenylglycine aminotransferase.
AN   D-hydroxyphenylglycine aminotransferase.
CA   D-4-hydroxyphenylglycine + 2-oxoglutarate = 4-hydroxyphenylglyoxylate +
CA   L-glutamate.
CF   Pyridoxal 5'-phosphate.
//
ID   2.6.1.73
DE   Methionine--glyoxylate transaminase.
AN   MGAT.
CA   L-methionine + glyoxylate = 4-methylthio-2-oxobutanoate + glycine.
CC   -!- L-glutamate can also act as donor.
//
ID   2.6.1.74
DE   Cephalosporin-C transaminase.
AN   Cephalosporin C aminotransferase.
CA   (7R)-7-(5-carboxy-5-oxopentanoyl)aminocephalosporinate + D-glutamate =
CA   cephalosporin C + 2-oxoglutarate.
CC   -!- A number of D-amino acids, including D-alanine, D-aspartate and
CC       D-methionine can also act as amino-group donors.
CC   -!- Although this enzyme acts on several free D-amino acids, it differs
CC       from EC 2.6.1.21 in that it can use cephalosporin C as an amino
CC       donor.
//
ID   2.6.1.75
DE   Cysteine-conjugate transaminase.
CA   S-(4-bromophenyl)-L-cysteine + 2-oxoglutarate = S-(4-bromophenyl)-
CA   mercaptopyruvate + L-glutamate.
CC   -!- A number of cysteine conjugates can also act.
//
ID   2.6.1.76
DE   Diaminobutyrate--2-oxoglutarate transaminase.
AN   2,4-diaminobutyrate 4-aminotransferase.
AN   DAB aminotransferase.
AN   DABA aminotransferase.
AN   Diaminibutyric acid aminotransferase.
AN   Diaminobutyrate transaminase.
AN   Diaminobutyrate--2-oxoglutarate aminotransferase.
CA   L-2,4-diaminobutanoate + 2-oxoglutarate = L-aspartate 4-semialdehyde +
CA   L-glutamate.
CF   Potassium; Pyridoxal 5'-phosphate.
CC   -!- Differs from EC 2.6.1.46, which has pyruvate as the amino-group
CC       acceptor.
CC   -!- This is the first enzyme in the ectoine biosynthesis pathway,
CC       the other enzymes involved being EC 2.3.1.178 and EC 4.2.1.108.
PR   PROSITE; PDOC00519;
DR   P56744, DAT_ACIBA  ;  P44951, DAT_HAEIN  ;  Q9KED4, ECTB_BACHD ;
DR   Q9AP34, ECTB_BACPA ;  Q5WL78, ECTB_BACSK ;  Q7WHI8, ECTB_BORBR ;
DR   Q7W979, ECTB_BORPA ;  Q9ZEU7, ECTB_CHRSD ;  O52250, ECTB_HALED ;
DR   O06060, ECTB_MARHA ;  Q5YW77, ECTB_NOCFA ;  Q8ESU8, ECTB_OCEIH ;
DR   Q6QUY9, ECTB_STRAQ ;  Q829L4, ECTB_STRAW ;  Q93RW1, ECTB_STRCO ;
DR   Q9KLC2, ECTB_VIBCH ;  Q87NZ7, ECTB_VIBPA ;  Q6PR32, ECTB_VIRPA ;
DR   Q7M9K2, ECTB_WOLSU ;  Q9Z3R2, RHBA_RHIME ;
//
ID   2.6.1.77
DE   Taurine--pyruvate aminotransferase.
CA   Taurine + pyruvate = L-alanine + 2-sulfoacetaldehyde.
CF   Pyridoxal 5'-phosphate.
CC   -!- The enzyme from Bilophila wadsworthia is reversible, and catalyzes
CC       the first step of anaerobic taurine degradation.
CC   -!- Hypotaurine (i.e. 2-aminoethanesulfinate) and beta-alanine are also
CC       significant donors of an amino group.
CC   -!- Unlike, EC 2.6.1.55, 2-oxoglutarate is not an acceptor of amino
CC       groups.
PR   PROSITE; PDOC00519;
DR   Q9APM5, TPA_BILWA  ;
//
ID   2.6.1.78
DE   Aspartate--prephenate aminotransferase.
AN   L-aspartate:prephenate aminotransferase.
AN   PAT.
AN   Prephenate aspartate aminotransferase.
AN   Prephenate transaminase.
CA   L-arogenate + oxaloacetate = prephenate + L-aspartate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Glutamate can also act as the amino donor, but more slowly (cf.
CC       EC 2.6.1.79).
DR   Q9SIE1, PAT_ARATH  ;
//
ID   2.6.1.79
DE   Glutamate--prephenate aminotransferase.
AN   L-glutamate:prephenate aminotransferase.
AN   PAT.
AN   Prephenate transaminase.
CA   L-arogenate + 2-oxoglutarate = prephenate + L-glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Aspartate can also act as the amino donor, but more slowly (cf.
CC       EC 2.6.1.78).
CC   -!- The enzyme from higher plants shows a marked preference for
CC       prephenate as substrate compared to pyruvate, phenylpyruvate or
CC       4-hydroxyphenylpyruvate.
DR   Q9SIE1, PAT_ARATH  ;
//
ID   2.6.1.80
DE   Nicotianamine aminotransferase.
AN   NAAT.
AN   NAAT-I.
AN   NAAT-II.
AN   NAAT-III.
AN   Nicotianamine transaminase.
CA   Nicotianamine + 2-oxoglutarate = 3''-deamino-3''-oxonicotianamine +
CA   L-glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- This enzyme is produced by grasses.
CC   -!- They secrete both the nicotianamine and the transaminated product
CC       into the soil around them.
CC   -!- Both compounds chelate Fe(2+) and Fe(3+); these chelators, called
CC       mugineic acid family phytosiderophores, are taken up by the grass,
CC       which is thereby supplied with iron.
DR   Q9ST02, NAATA_HORVU;  Q9ST03, NAATB_HORVU;
//
ID   2.6.1.81
DE   Succinylornithine transaminase.
AN   N(2)-succinylornithine 5-aminotransferase.
AN   SOAT.
AN   Succinylornithine aminotransferase.
CA   N(2)-succinyl-L-ornithine + 2-oxoglutarate = N-succinyl-L-glutamate
CA   5-semialdehyde + L-glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Also acts on N(2)-acetyl-L-ornithine and L-ornithine, but more
CC       slowly.
CC   -!- In Pseudomonas aeruginosa, the arginine-inducible succinylornithine
CC       transaminase, EC 2.6.1.11 and EC 2.6.1.13 activities are catalyzed by
CC       the same enzyme, but this is not the case in all species.
CC   -!- This is the third enzyme in the arginine succinyltransferase (AST)
CC       pathway for the catabolism of arginine.
CC   -!- This pathway converts the carbon skeleton of arginine into glutamate,
CC       with the concomitant production of ammonia and conversion of
CC       succinyl-CoA into succinate and CoA.
CC   -!- The five enzymes involved in this pathway are EC 2.3.1.109,
CC       EC 3.5.3.23, EC 2.6.1.81, EC 1.2.1.71 and EC 3.5.1.96.
PR   PROSITE; PDOC00519;
DR   O30508, ARUC_PSEAE ;  Q9AAL3, ASTC_CAUCR ;  A8AHE0, ASTC_CITK8 ;
DR   A7ZML6, ASTC_ECO24 ;  B7USC9, ASTC_ECO27 ;  B7MAV9, ASTC_ECO45 ;
DR   B7L6M2, ASTC_ECO55 ;  Q8X598, ASTC_ECO57 ;  B5YQ35, ASTC_ECO5E ;
DR   B7NT29, ASTC_ECO7I ;  B7MVM7, ASTC_ECO81 ;  B7M1G0, ASTC_ECO8A ;
DR   C4ZZA4, ASTC_ECOBW ;  B1XGK9, ASTC_ECODH ;  A8A0U0, ASTC_ECOHS ;
DR   A1ABS9, ASTC_ECOK1 ;  Q0TH82, ASTC_ECOL5 ;  Q8FGZ9, ASTC_ECOL6 ;
DR   B1IPI2, ASTC_ECOLC ;  P77581, ASTC_ECOLI ;  B7N584, ASTC_ECOLU ;
DR   B6IBG8, ASTC_ECOSE ;  B1LDY3, ASTC_ECOSM ;  Q1RB45, ASTC_ECOUT ;
DR   B7LQ44, ASTC_ESCF3 ;  Q7N2G7, ASTC_PHOLL ;  B5F846, ASTC_SALA4 ;
DR   Q57PX9, ASTC_SALCH ;  B5FJD8, ASTC_SALDC ;  B5QWJ0, ASTC_SALEP ;
DR   B5RB01, ASTC_SALG2 ;  B4TGE0, ASTC_SALHS ;  B4T3Z4, ASTC_SALNS ;
DR   Q5PHC8, ASTC_SALPA ;  A9N278, ASTC_SALPB ;  C0Q6X9, ASTC_SALPC ;
DR   B5BA72, ASTC_SALPK ;  Q8Z6F9, ASTC_SALTI ;  Q8ZPV2, ASTC_SALTY ;
DR   B2U3D0, ASTC_SHIB3 ;  Q321P0, ASTC_SHIBS ;  Q3Z295, ASTC_SHISS ;
DR   A1JS45, ASTC_YERE8 ;  A7FIL6, ASTC_YERP3 ;  Q1C8B1, ASTC_YERPA ;
DR   Q8D0D7, ASTC_YERPE ;  A9QZ63, ASTC_YERPG ;  Q66B21, ASTC_YERPS ;
//
ID   2.6.1.82
DE   Putrescine aminotransferase.
AN   PAT.
AN   Putrescine transaminase.
AN   Putrescine-alpha-ketoglutarate transaminase.
CA   Putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H(2)O.
CF   Pyridoxal 5'-phosphate.
CC   -!- The enzymatic part of the reaction produces 4-aminobutanal that
CC       spontaneously cyclizes to form 1-pyrroline, which is a substrate for
CC       EC 1.2.1.19.
CC   -!- Cadaverine and spermidine can also act as substrates.
CC   -!- Forms part of the arginine catabolism pathway.
PR   PROSITE; PDOC00519;
DR   A8APX8, PAT_CITK8  ;  A7ZRV6, PAT_ECO24  ;  B7UIY0, PAT_ECO27  ;
DR   B7MB08, PAT_ECO45  ;  B7LH08, PAT_ECO55  ;  Q8XAN1, PAT_ECO57  ;
DR   B5YRB3, PAT_ECO5E  ;  B7NJT8, PAT_ECO7I  ;  B7N0M2, PAT_ECO81  ;
DR   B7LZM2, PAT_ECO8A  ;  C4ZQY9, PAT_ECOBW  ;  B1XG77, PAT_ECODH  ;
DR   A8A4N0, PAT_ECOHS  ;  A1AFZ3, PAT_ECOK1  ;  Q0TD34, PAT_ECOL5  ;
DR   Q8FDF5, PAT_ECOL6  ;  B1IRP4, PAT_ECOLC  ;  P42588, PAT_ECOLI  ;
DR   B7ND61, PAT_ECOLU  ;  B6I445, PAT_ECOSE  ;  B1LF65, PAT_ECOSM  ;
DR   Q1R6Q7, PAT_ECOUT  ;  A4WEQ6, PAT_ENT38  ;  A7MIU0, PAT_ENTS8  ;
DR   Q6D6Y6, PAT_ERWCT  ;  B7LQF8, PAT_ESCF3  ;  B5XTY7, PAT_KLEP3  ;
DR   A6TEB2, PAT_KLEP7  ;  B5F6B4, PAT_SALA4  ;  A9MPU4, PAT_SALAR  ;
DR   Q57JP1, PAT_SALCH  ;  B5FHV3, PAT_SALDC  ;  B5QZ53, PAT_SALEP  ;
DR   B5REH5, PAT_SALG2  ;  B4TIU6, PAT_SALHS  ;  B4T688, PAT_SALNS  ;
DR   Q5PC95, PAT_SALPA  ;  A9N5Z8, PAT_SALPB  ;  C0PYZ1, PAT_SALPC  ;
DR   B5BG29, PAT_SALPK  ;  B4TVV2, PAT_SALSV  ;  Q8Z3L9, PAT_SALTI  ;
DR   Q8ZLX7, PAT_SALTY  ;  Q31WW1, PAT_SHIBS  ;  Q0T0J2, PAT_SHIF8  ;
DR   Q83JJ8, PAT_SHIFL  ;  Q3YXH0, PAT_SHISS  ;
//
ID   2.6.1.83
DE   LL-diaminopimelate aminotransferase.
AN   LL-DAP aminotransferase.
AN   LL-DAP-AT.
AN   LL-diaminopimelate transaminase.
CA   LL-2,6-diaminoheptanedioate + 2-oxoglutarate = (S)-2,3,4,5-
CA   tetrahydropyridine-2,6-dicarboxylate + L-glutamate + H(2)O.
CF   Pyridoxal 5'-phosphate.
CC   -!- In vivo, the reaction occurs in the opposite direction to that shown
CC       above.
CC   -!- This is one of the final steps in the lysine biosynthesis pathway of
CC       plants (ranging from mosses to flowering plants).
CC   -!- Meso-diaminoheptanedioate, an isomer of LL-2,6-diaminoheptanedioate,
CC       and the structurally related compounds lysine and ornithine are not
CC       substrates.
CC   -!- 2-oxoglutarate cannot be replaced by oxaloacetate or pyruvate.
CC   -!- It is not yet known if the substrate of the biosynthetic reaction is
CC       the cyclic or acyclic form of tetrahydropyridine-2,6-dicarboxylate.
PR   PROSITE; PDOC00098;
DR   B0CDH5, DAPAT_ACAM1;  O66630, DAPAT_AQUAE;  Q93ZN9, DAPAT_ARATH;
DR   B6YRL2, DAPAT_AZOPC;  Q5LC03, DAPAT_BACFN;  Q64SY6, DAPAT_BACFR;
DR   Q8AAB8, DAPAT_BACTN;  A6L7E4, DAPAT_BACV8;  Q3AC10, DAPAT_CARHZ;
DR   Q5L6M0, DAPAT_CHLAB;  Q824A4, DAPAT_CHLCV;  Q253K9, DAPAT_CHLFF;
DR   Q9PK04, DAPAT_CHLMU;  Q9Z856, DAPAT_CHLPN;  B0B7W0, DAPAT_CHLT2;
DR   Q3KLW3, DAPAT_CHLTA;  B0BC25, DAPAT_CHLTB;  O84395, DAPAT_CHLTR;
DR   A9KJ19, DAPAT_CLOPH;  A3DK17, DAPAT_CLOTH;  B1WSG7, DAPAT_CYAA5;
DR   B8HJY4, DAPAT_CYAP4;  B7KL61, DAPAT_CYAP7;  B7JVL5, DAPAT_CYAP8;
DR   Q3Z8H5, DAPAT_DEHE1;  A5FRC5, DAPAT_DEHSB;  Q3ZXC8, DAPAT_DEHSC;
DR   C6BUK3, DAPAT_DESAD;  C0QFJ4, DAPAT_DESAH;  B1I544, DAPAT_DESAP;
DR   B8IZX8, DAPAT_DESDA;  Q30ZX9, DAPAT_DESDG;  Q18T09, DAPAT_DESHD;
DR   Q24S01, DAPAT_DESHY;  A8ZXV5, DAPAT_DESOH;  Q6AL81, DAPAT_DESPS;
DR   Q72BI1, DAPAT_DESVH;  B8DJJ6, DAPAT_DESVM;  A1VDD3, DAPAT_DESVV;
DR   C4Z4Y1, DAPAT_EUBE2;  C4ZG66, DAPAT_EUBR3;  B5EGX2, DAPAT_GEOBB;
DR   B3E933, DAPAT_GEOLS;  Q39Z65, DAPAT_GEOMG;  B9M384, DAPAT_GEOSF;
DR   Q74GT3, DAPAT_GEOSL;  C6E9Q7, DAPAT_GEOSM;  A5GD93, DAPAT_GEOUR;
DR   Q7NDX4, DAPAT_GLOVI;  B8CX89, DAPAT_HALOH;  B0TA38, DAPAT_HELMI;
DR   Q1MR87, DAPAT_LAWIP;  B0SEH8, DAPAT_LEPBA;  Q04UL5, DAPAT_LEPBJ;
DR   Q04YV8, DAPAT_LEPBL;  B0SMK7, DAPAT_LEPBP;  Q72NJ3, DAPAT_LEPIC;
DR   Q8F814, DAPAT_LEPIN;  Q58786, DAPAT_METJA;  Q6LX26, DAPAT_METMP;
DR   A5UN82, DAPAT_METS3;  Q2NFU1, DAPAT_METST;  O26158, DAPAT_METTH;
DR   B0JUM0, DAPAT_MICAN;  Q2RK33, DAPAT_MOOTA;  B2A250, DAPAT_NATTJ;
DR   B2J2U3, DAPAT_NOSP7;  A6L8U2, DAPAT_PARD8;  Q6MDE0, DAPAT_PARUW;
DR   Q3A1U5, DAPAT_PELCD;  A1ATI6, DAPAT_PELPD;  A3PEY9, DAPAT_PROM0;
DR   A2C4T7, DAPAT_PROM1;  A2CC97, DAPAT_PROM3;  A9BCJ1, DAPAT_PROM4;
DR   A2BYM6, DAPAT_PROM5;  Q318P3, DAPAT_PROM9;  Q7VA14, DAPAT_PROMA;
DR   Q7V4Z3, DAPAT_PROMM;  Q7UZZ3, DAPAT_PROMP;  A2BT75, DAPAT_PROMS;
DR   Q46IX2, DAPAT_PROMT;  Q31PY6, DAPAT_SYNE7;  A0LEA5, DAPAT_SYNFM;
DR   Q2JS04, DAPAT_SYNJA;  Q2JLL9, DAPAT_SYNJB;  B1XKF6, DAPAT_SYNP2;
DR   Q5N492, DAPAT_SYNP6;  A5GIN1, DAPAT_SYNPW;  Q7U4C3, DAPAT_SYNPX;
DR   A5GW23, DAPAT_SYNR3;  Q0ID68, DAPAT_SYNS3;  Q3AW44, DAPAT_SYNS9;
DR   Q3AMU5, DAPAT_SYNSC;  Q55828, DAPAT_SYNY3;  Q8DH57, DAPAT_THEEB;
DR   Q10ZC3, DAPAT_TRIEI;  Q3MAL4, DAPT1_ANAVT;  Q8YM38, DAPT1_NOSS1;
DR   Q3MDN5, DAPT2_ANAVT;  Q8YP73, DAPT2_NOSS1;
//
ID   2.6.1.84
DE   Arginine--pyruvate transaminase.
AN   Arginine:pyruvate transaminase.
CA   L-arginine + pyruvate = 5-guanidino-2-oxopentanoate + L-alanine.
CF   Pyridoxal 5'-phosphate.
CC   -!- While L-arginine is the best substrate, the enzyme exhibits broad
CC       substrate specificity, with L-lysine, L-methionine, L-leucine,
CC       L-ornithine and L-glutamine also able to act as substrates, but more
CC       slowly.
CC   -!- Pyruvate cannot be replaced by 2-oxoglutarate as amino-group
CC       acceptor.
CC   -!- This is the first catalytic enzyme of the arginine transaminase
CC       pathway for L-arginine utilization in Pseudomonas aeruginosa.
CC   -!- This pathway is only used when the major route of arginine
CC       catabolism, i.e. the arginine succinyltransferase pathway,
CC       is blocked.
//
ID   2.6.1.85
DE   Aminodeoxychorismate synthase.
AN   4-amino-4-deoxychorismate synthase.
AN   ADC synthase.
CA   Chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate.
CF   Magnesium.
CC   -!- Composed of two subunits, PabA and PabB.
CC   -!- In the absence of PabA and glutamine, PabB converts ammonia and
CC       chorismate into 4-amino-4-deoxychorismate.
CC   -!- PabA converts glutamine into glutamate only in the presence of
CC       stoichiometric amounts of PabB.
CC   -!- Coupled with EC 4.1.3.38, to form 4-aminobenzoate.
CC   -!- Formerly EC 6.3.5.8.
PR   PROSITE; PDOC00948;
DR   P28819, PABA_BACSU ;  P00903, PABA_ECOLI ;  P06194, PABA_ENTAE ;
DR   P06193, PABA_SALTY ;  P06195, PABA_SERMA ;  P27627, PABA_STRLI ;
DR   P28820, PABB_BACSU ;  P05041, PABB_ECOLI ;  P12679, PABB_ENTAE ;
DR   P27629, PABB_LACLA ;  P12680, PABB_SALTY ;  P27630, PABB_STRLI ;
DR   O94277, PABS_SCHPO ;  P32483, PABS_STRGR ;  P37254, PABS_YEAST ;
//
ID   2.6.1.86
DE   2-amino-4-deoxychorismate synthase.
AN   2-amino-2-deoxyisochorismate synthase.
AN   ADIC synthase.
CA   (2S)-2-amino-4-deoxychorismate + L-glutamate = chorismate + L-glutamine.
CF   Magnesium.
CC   -!- The reaction occurs in the reverse direction to that shown above.
CC   -!- In contrast to most anthranilate-synthase I (ASI) homologs, this
CC       enzyme is not inhibited by tryptophan.
CC   -!- In Streptomyces globisporus, the sequential action of this enzyme and
CC       EC 1.3.99.24, 2-amino-4-deoxychorismate dehydrogenase, leads to the
CC       formation of the benzoxazolinate moiety of the enediyne antitumor
CC       antibiotic C-1027.
CC   -!- In certain Pseudomonads the enzyme participates in the biosynthesis
CC       of phenazine, a precursor for several compounds with antibiotic
CC       activity.
//
ID   2.6.1.87
DE   UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
AN   UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase.
AN   UDP-4-amino-4-deoxy-L-arabinose aminomutase.
AN   UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase.
AN   UDP-Ara4O aminotransferase.
AN   UDP-L-Ara4N transaminase.
CA   UDP-4-amino-4-deoxy-beta-L-arabinose + 2-oxoglutarate = UDP-beta-L-threo-
CA   pentapyranos-4-ulose + glutamate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Formerly EC 2.6.1.n1.
DR   A0KGY8, ARNB_AERHH ;  A4SQW7, ARNB_AERS4 ;  A7ZP71, ARNB_ECO24 ;
DR   B7UFR5, ARNB_ECO27 ;  B7MG20, ARNB_ECO45 ;  B7LAR8, ARNB_ECO55 ;
DR   Q7AC24, ARNB_ECO57 ;  B5YX44, ARNB_ECO5E ;  B7NNT2, ARNB_ECO7I ;
DR   B7MXT4, ARNB_ECO81 ;  B7M5T5, ARNB_ECO8A ;  C4ZU95, ARNB_ECOBW ;
DR   B1X8W6, ARNB_ECODH ;  A8A2C0, ARNB_ECOHS ;  A1ADA5, ARNB_ECOK1 ;
DR   Q0TFI9, ARNB_ECOL5 ;  Q8FFM3, ARNB_ECOL6 ;  B1IXT4, ARNB_ECOLC ;
DR   P77690, ARNB_ECOLI ;  B7N5L8, ARNB_ECOLU ;  B6I7J6, ARNB_ECOSE ;
DR   B1LLK7, ARNB_ECOSM ;  Q1R9G2, ARNB_ECOUT ;  C5BDQ4, ARNB_EDWI9 ;
DR   A4WAM5, ARNB_ENT38 ;  Q6D2E9, ARNB_ERWCT ;  B2VBJ1, ARNB_ERWT9 ;
DR   B7LM78, ARNB_ESCF3 ;  B5XTK7, ARNB_KLEP3 ;  A6TFA0, ARNB_KLEP7 ;
DR   C6DAW7, ARNB_PECCP ;  Q7N3Q5, ARNB_PHOLL ;  B4ETL5, ARNB_PROMH ;
DR   A6V1P2, ARNB_PSEA7 ;  B7VBN4, ARNB_PSEA8 ;  Q02R23, ARNB_PSEAB ;
DR   Q9HY65, ARNB_PSEAE ;  Q4KC84, ARNB_PSEF5 ;  Q3KCC3, ARNB_PSEPF ;
DR   Q4ZSZ4, ARNB_PSEU2 ;  B5EZH6, ARNB_SALA4 ;  Q57M57, ARNB_SALCH ;
DR   B5FNT7, ARNB_SALDC ;  B5R270, ARNB_SALEP ;  B5RCC2, ARNB_SALG2 ;
DR   B4TBG4, ARNB_SALHS ;  B4SYW9, ARNB_SALNS ;  Q5PNA4, ARNB_SALPA ;
DR   A9N5B4, ARNB_SALPB ;  C0Q071, ARNB_SALPC ;  B5BCP8, ARNB_SALPK ;
DR   B4TPI0, ARNB_SALSV ;  Q8Z542, ARNB_SALTI ;  Q8ZNF3, ARNB_SALTY ;
DR   A8GDR5, ARNB_SERP5 ;  A8FRR4, ARNB_SHESH ;  Q31YK4, ARNB_SHIBS ;
DR   Q0T2N0, ARNB_SHIF8 ;  Q83QT9, ARNB_SHIFL ;  Q3YZV3, ARNB_SHISS ;
DR   Q2NRV5, ARNB_SODGM ;  A1JPP9, ARNB_YERE8 ;  A7FHH2, ARNB_YERP3 ;
DR   Q1C740, ARNB_YERPA ;  B2K5L5, ARNB_YERPB ;  Q93PE0, ARNB_YERPE ;
DR   A9R095, ARNB_YERPG ;  Q1CIH5, ARNB_YERPN ;  A4TIM2, ARNB_YERPP ;
DR   Q7BF87, ARNB_YERPS ;  B1JJ28, ARNB_YERPY ;
//
ID   2.6.1.n1
DE   Transferred entry: 2.6.1.87.
//
ID   2.6.2.1
DE   Transferred entry: 2.1.4.1.
//
ID   2.6.3.1
DE   Oximinotransferase.
AN   Oximase.
AN   Pyruvate-acetone oximinotransferase.
AN   Transoximinase.
CA   Pyruvate oxime + acetone = pyruvate + acetone oxime.
CC   -!- Acetaldehyde can act instead of acetone; D-glucose oxime can act
CC       instead of pyruvate oxime.
//
ID   2.6.99.1
DE   dATP(dGTP)--DNA purinetransferase.
CA   (1) dATP + depurinated DNA = deoxyribose triphosphate + DNA.
CA   (2) dGTP + depurinated DNA = deoxyribose triphosphate + DNA.
CC   -!- The purine residue is transferred on to the apurinic site forming a
CC       normal glycosylic bond.
CC   -!- dATP reacts at sites of the double-stranded depurinated DNA that lack
CC       adenine, and dGTP at sites that lack guanine.
//
ID   2.6.99.2
DE   Pyridoxine 5'-phosphate synthase.
AN   PNP synthase.
AN   Pyridoxine 5-phosphate phospho lyase.
CA   1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate =
CA   pyridoxine 5'-phosphate + phosphate + 2 H(2)O.
CC   -!- In Escherichia coli, the coenzyme pyridoxal 5'-phosphate is
CC       synthesized de novo by a pathway that involves EC 1.2.1.72,
CC       EC 1.1.1.290, EC 2.6.1.52, EC 1.1.1.262, EC 2.6.99.2 and EC 1.4.3.5.
CC   -!- 1-deoxy-D-xylulose cannot replace 1-deoxy-D-xylulose 5-phosphate as a
CC       substrate.
DR   B0C977, PDXJ_ACAM1 ;  Q3V7G6, PDXJ_ACIAD ;  B7J9K4, PDXJ_ACIF2 ;
DR   B5EQL6, PDXJ_ACIF5 ;  Q8UDU5, PDXJ_AGRT5 ;  B9JXN7, PDXJ_AGRVS ;
DR   B2URE7, PDXJ_AKKM8 ;  Q0VP22, PDXJ_ALCBS ;  Q3V7J9, PDXJ_ANAMM ;
DR   Q2GJT4, PDXJ_ANAPZ ;  Q3M9L4, PDXJ_ANAVT ;  O67417, PDXJ_AQUAE ;
DR   P46212, PDXJ_AQUPY ;  A8ESJ1, PDXJ_ARCB4 ;  Q5P083, PDXJ_AROAE ;
DR   A1K607, PDXJ_AZOSB ;  C1DQS7, PDXJ_AZOVD ;  Q5L912, PDXJ_BACFN ;
DR   Q3V814, PDXJ_BACFR ;  Q8A0V3, PDXJ_BACTN ;  A6KXM3, PDXJ_BACV8 ;
DR   Q3V7R4, PDXJ_BDEBA ;  Q7VRR1, PDXJ_BLOFL ;  Q492D2, PDXJ_BLOPB ;
DR   Q2KXM4, PDXJ_BORA1 ;  Q7WH63, PDXJ_BORBR ;  Q7W9J7, PDXJ_BORPA ;
DR   A9IUY4, PDXJ_BORPD ;  Q7VWW0, PDXJ_BORPE ;  O69158, PDXJ_BRAJA ;
DR   A4YWD1, PDXJ_BRASO ;  B2S6L0, PDXJ_BRUA1 ;  Q2YQM7, PDXJ_BRUA2 ;
DR   Q57CC2, PDXJ_BRUAB ;  A9M642, PDXJ_BRUC2 ;  C0RE25, PDXJ_BRUMB ;
DR   Q8YI24, PDXJ_BRUME ;  A5VRD3, PDXJ_BRUO2 ;  B0CHH2, PDXJ_BRUSI ;
DR   Q8FZT6, PDXJ_BRUSU ;  Q3V7M2, PDXJ_BURMA ;  Q3JQ80, PDXJ_BURP1 ;
DR   Q3V7S9, PDXJ_BURPS ;  Q39I70, PDXJ_BURS3 ;  A0RNS2, PDXJ_CAMFF ;
DR   A7I3Y5, PDXJ_CAMHC ;  A8FMU3, PDXJ_CAMJ8 ;  A7H2E1, PDXJ_CAMJD ;
DR   Q9PN59, PDXJ_CAMJE ;  A1W0M1, PDXJ_CAMJJ ;  Q5HTM5, PDXJ_CAMJR ;
DR   B9KCG6, PDXJ_CAMLR ;  B8H623, PDXJ_CAUCN ;  Q9A808, PDXJ_CAUCR ;
DR   B0T3H6, PDXJ_CAUSK ;  Q3ATB8, PDXJ_CHLCH ;  B3QQ93, PDXJ_CHLP8 ;
DR   B3ELU3, PDXJ_CHLPB ;  A1BE95, PDXJ_CHLPD ;  B3QTV1, PDXJ_CHLT3 ;
DR   Q8KFJ5, PDXJ_CHLTE ;  Q7NWC0, PDXJ_CHRVO ;  Q47WP8, PDXJ_COLP3 ;
DR   A9KFA7, PDXJ_COXBN ;  A9N936, PDXJ_COXBR ;  Q83BL1, PDXJ_COXBU ;
DR   Q0K8N6, PDXJ_CUPNH ;  Q46Z21, PDXJ_CUPPJ ;  B3R1Z6, PDXJ_CUPTR ;
DR   B1WY64, PDXJ_CYAA5 ;  B8HKL1, PDXJ_CYAP4 ;  B7K7E4, PDXJ_CYAP7 ;
DR   Q11PM4, PDXJ_CYTH3 ;  Q47EF4, PDXJ_DECAR ;  B8FJ89, PDXJ_DESAA ;
DR   C6BV77, PDXJ_DESAD ;  C0Q9S7, PDXJ_DESAH ;  Q30ZQ6, PDXJ_DESDG ;
DR   C4XGU0, PDXJ_DESMR ;  A8ZVC5, PDXJ_DESOH ;  Q3V891, PDXJ_DESVH ;
DR   B8DPF1, PDXJ_DESVM ;  A1VCV9, PDXJ_DESVV ;  P0A795, PDXJ_ECO57 ;
DR   Q8FF18, PDXJ_ECOL6 ;  P0A794, PDXJ_ECOLI ;  Q3YSI5, PDXJ_EHRCJ ;
DR   Q2GG30, PDXJ_EHRCR ;  Q5FHH4, PDXJ_EHRRG ;  Q5HBN7, PDXJ_EHRRW ;
DR   B2KEC4, PDXJ_ELUMP ;  Q3V7N3, PDXJ_ERWCT ;  A5FJ95, PDXJ_FLAJ1 ;
DR   B5EHA6, PDXJ_GEOBB ;  B3E693, PDXJ_GEOLS ;  Q39UG0, PDXJ_GEOMG ;
DR   B9M5K2, PDXJ_GEOSF ;  Q3V8C9, PDXJ_GEOSL ;  C6E5P6, PDXJ_GEOSM ;
DR   A5G535, PDXJ_GEOUR ;  Q7NPF2, PDXJ_GLOVI ;  Q5FNS2, PDXJ_GLUOX ;
DR   A0LXW0, PDXJ_GRAFK ;  Q17ZN1, PDXJ_HELAH ;  Q7VHV1, PDXJ_HELHP ;
DR   B6JP91, PDXJ_HELP2 ;  B5Z9L2, PDXJ_HELPG ;  Q1CR25, PDXJ_HELPH ;
DR   Q9ZJ29, PDXJ_HELPJ ;  B2UVZ8, PDXJ_HELPS ;  O26102, PDXJ_HELPY ;
DR   B4U872, PDXJ_HYDS0 ;  Q5R109, PDXJ_IDILO ;  Q28V29, PDXJ_JANSC ;
DR   C1D7L7, PDXJ_LARHH ;  Q3V7G1, PDXJ_LEGPA ;  A5IFW5, PDXJ_LEGPC ;
DR   Q3V870, PDXJ_LEGPH ;  Q3V7F6, PDXJ_LEGPL ;  B0SBH6, PDXJ_LEPBA ;
DR   B0SJ25, PDXJ_LEPBP ;  A0L8S5, PDXJ_MAGSM ;  Q11I86, PDXJ_MESSB ;
DR   Q3V8A2, PDXJ_METCA ;  B3DF93, PDXJ_MICAN ;  B9LAE4, PDXJ_NAUPA ;
DR   Q5F6P1, PDXJ_NEIG1 ;  A9M276, PDXJ_NEIM0 ;  Q9RQV9, PDXJ_NEIMA ;
DR   Q9K0V9, PDXJ_NEIMB ;  Q9RML6, PDXJ_NEIMC ;  A1KVH8, PDXJ_NEIMF ;
DR   Q0AF72, PDXJ_NITEC ;  Q82SJ7, PDXJ_NITEU ;  Q2Y865, PDXJ_NITMU ;
DR   Q3JCY8, PDXJ_NITOC ;  A6Q3Y6, PDXJ_NITSB ;  Q3SRB0, PDXJ_NITWN ;
DR   B2J448, PDXJ_NOSP7 ;  Q8Z080, PDXJ_NOSS1 ;  A6WZX2, PDXJ_OCHA4 ;
DR   B1ZNA6, PDXJ_OPITP ;  A6LC86, PDXJ_PARD8 ;  Q3A5V4, PDXJ_PELCD ;
DR   Q3B5P7, PDXJ_PELLD ;  B4SDS5, PDXJ_PELPB ;  A1AR94, PDXJ_PELPD ;
DR   Q4FLS6, PDXJ_PELUB ;  C0QU74, PDXJ_PERMH ;  Q7N1X8, PDXJ_PHOLL ;
DR   Q3V7I6, PDXJ_PHOPR ;  B2RIJ5, PDXJ_PORG3 ;  Q51843, PDXJ_PORGI ;
DR   B4S3G9, PDXJ_PROA2 ;  A2C3H1, PDXJ_PROM1 ;  A8G5H7, PDXJ_PROM2 ;
DR   A2C897, PDXJ_PROM3 ;  A9BAZ9, PDXJ_PROM4 ;  A2BX94, PDXJ_PROM5 ;
DR   Q31AB8, PDXJ_PROM9 ;  Q7VBK3, PDXJ_PROMA ;  Q7V6Q5, PDXJ_PROMM ;
DR   Q7V0Y7, PDXJ_PROMP ;  A2BRT6, PDXJ_PROMS ;  Q46K45, PDXJ_PROMT ;
DR   A4SDF7, PDXJ_PROVI ;  Q48EV6, PDXJ_PSE14 ;  A6VAK3, PDXJ_PSEA7 ;
DR   B7UYW9, PDXJ_PSEA8 ;  Q02HS5, PDXJ_PSEAB ;  Q9I5G5, PDXJ_PSEAE ;
DR   Q1I5W1, PDXJ_PSEE4 ;  Q4KHS8, PDXJ_PSEF5 ;  C3K6Z0, PDXJ_PSEFS ;
DR   Q3IDK9, PDXJ_PSEHT ;  A4XSC7, PDXJ_PSEMY ;  A5W8E9, PDXJ_PSEP1 ;
DR   Q3KHL6, PDXJ_PSEPF ;  B0KV24, PDXJ_PSEPG ;  Q88MY2, PDXJ_PSEPK ;
DR   B1J4E3, PDXJ_PSEPW ;  Q87XG4, PDXJ_PSESM ;  Q4ZPE4, PDXJ_PSEU2 ;
DR   A4VIX8, PDXJ_PSEU5 ;  Q4FUV3, PDXJ_PSYA2 ;  Q1QDV0, PDXJ_PSYCK ;
DR   Q1LKN4, PDXJ_RALME ;  B2U984, PDXJ_RALPJ ;  Q8Y0H8, PDXJ_RALSO ;
DR   Q98KL6, PDXJ_RHILO ;  Q92NT6, PDXJ_RHIME ;  Q7UYK5, PDXJ_RHOBA ;
DR   Q21XM2, PDXJ_RHOFD ;  Q2IWU8, PDXJ_RHOP2 ;  Q3V7S0, PDXJ_RHOPA ;
DR   Q214J9, PDXJ_RHOPB ;  Q136W2, PDXJ_RHOPS ;  B3QJH1, PDXJ_RHOPT ;
DR   Q2RT91, PDXJ_RHORT ;  A3PGF5, PDXJ_RHOS1 ;  Q3J5W4, PDXJ_RHOS4 ;
DR   Q16AJ0, PDXJ_ROSDO ;  Q57LD3, PDXJ_SALCH ;  Q3V7K1, PDXJ_SALPA ;
DR   Q2S0U5, PDXJ_SALRD ;  Q8Z4K6, PDXJ_SALTI ;  Q8ZN19, PDXJ_SALTY ;
DR   Q8EH78, PDXJ_SHEON ;  Q31XS3, PDXJ_SHIBS ;  Q32CV7, PDXJ_SHIDS ;
DR   Q3YYV2, PDXJ_SHISS ;  Q3V7J3, PDXJ_SILPO ;  Q30S57, PDXJ_SULDN ;
DR   A6QAX8, PDXJ_SULNB ;  B2V6U1, PDXJ_SULSY ;  Q8KPR0, PDXJ_SYNE7 ;
DR   A0LK96, PDXJ_SYNFM ;  Q2JSG7, PDXJ_SYNJA ;  Q2JP46, PDXJ_SYNJB ;
DR   Q3V812, PDXJ_SYNP6 ;  A5GLI2, PDXJ_SYNPW ;  Q7U7S1, PDXJ_SYNPX ;
DR   A5GU97, PDXJ_SYNR3 ;  Q0IB11, PDXJ_SYNS3 ;  Q3AVH3, PDXJ_SYNS9 ;
DR   Q3AJ26, PDXJ_SYNSC ;  P72776, PDXJ_SYNY3 ;  Q8DKM1, PDXJ_THEEB ;
DR   B5YGR4, PDXJ_THEYD ;  Q31HP0, PDXJ_THICR ;  Q3SH53, PDXJ_THIDA ;
DR   B8GPL4, PDXJ_THISH ;  Q10X41, PDXJ_TRIEI ;  Q9KPB5, PDXJ_VIBCH ;
DR   Q5E317, PDXJ_VIBF1 ;  Q87LP2, PDXJ_VIBPA ;  Q8DC73, PDXJ_VIBVU ;
DR   Q7MHP1, PDXJ_VIBVY ;  Q8D304, PDXJ_WIGBR ;  Q3V8B3, PDXJ_WOLPM ;
DR   B3CLF3, PDXJ_WOLPP ;  Q7MAP8, PDXJ_WOLSU ;  C0R576, PDXJ_WOLWR ;
DR   Q8PRF1, PDXJ_XANAC ;  Q3BZR9, PDXJ_XANC5 ;  Q4V0R7, PDXJ_XANC8 ;
DR   B0RLF1, PDXJ_XANCB ;  Q8PEG8, PDXJ_XANCP ;  Q2P9L0, PDXJ_XANOM ;
DR   B2SUX4, PDXJ_XANOP ;  Q5H704, PDXJ_XANOR ;  A7IM59, PDXJ_XANP2 ;
DR   B2I669, PDXJ_XYLF2 ;  Q9PH84, PDXJ_XYLFA ;  B0U2A9, PDXJ_XYLFM ;
DR   Q87F88, PDXJ_XYLFT ;  Q8ZCP4, PDXJ_YERPE ;  Q3V7P0, PDXJ_YERPS ;
DR   Q5NLS8, PDXJ_ZYMMO ;
//
ID   2.7.1.1
DE   Hexokinase.
AN   Hexokinase type I.
AN   Hexokinase type II.
AN   Hexokinase type III.
AN   Hexokinase type IV (glucokinase).
CA   ATP + D-hexose = ADP + D-hexose 6-phosphate.
CC   -!- D-glucose, D-mannose, D-fructose, sorbitol and D-glucosamine can act
CC       as acceptors.
CC   -!- ITP and dATP can act as donors.
PR   PROSITE; PDOC00370;
DR   Q2TB90, HKDC1_HUMAN;  Q91W97, HKDC1_MOUSE;  Q2KNB5, HXK10_ORYSJ;
DR   Q42525, HXK1_ARATH ;  Q4U3Y2, HXK1_ASPFU ;  P27595, HXK1_BOVIN ;
DR   Q9NFT9, HXK1_DROME ;  P19367, HXK1_HUMAN ;  P17710, HXK1_MOUSE ;
DR   Q8LH82, HXK1_ORYSJ ;  Q5RC71, HXK1_PONAB ;  P05708, HXK1_RAT   ;
DR   Q09756, HXK1_SCHPO ;  O64390, HXK1_SOLTU ;  Q9SEK3, HXK1_SPIOL ;
DR   Q9SEK2, HXK1_TOBAC ;  P93834, HXK2_ARATH ;  Q9NFT7, HXK2_DROME ;
DR   A2PYL8, HXK2_EQUGR ;  A2PYL7, HXK2_EQUZE ;  A2PYL6, HXK2_HORSE ;
DR   P52789, HXK2_HUMAN ;  O08528, HXK2_MOUSE ;  Q2KNB9, HXK2_ORYSJ ;
DR   Q1W674, HXK2_PIG   ;  P27881, HXK2_RAT   ;  P50521, HXK2_SCHPO ;
DR   Q9SQ76, HXK2_SOLTU ;  Q6Q8A5, HXK2_TOBAC ;  Q9LPS1, HXK3_ARATH ;
DR   P52790, HXK3_HUMAN ;  Q3TRM8, HXK3_MOUSE ;  Q2KNB4, HXK3_ORYSJ ;
DR   P27926, HXK3_RAT   ;  Q56XE8, HXK4_ARATH ;  Q6Z398, HXK4_ORYSJ ;
DR   Q5W676, HXK5_ORYSJ ;  Q8LQ68, HXK6_ORYSJ ;  Q1WM16, HXK7_ORYSJ ;
DR   Q1WM15, HXK8_ORYSJ ;  Q2KNB7, HXK9_ORYSJ ;  P04806, HXKA_YEAST ;
DR   P04807, HXKB_YEAST ;  Q9FZG4, HXKL1_ARATH;  Q9T071, HXKL2_ARATH;
DR   P80581, HXK_EMENI  ;  P33284, HXK_KLULA  ;  Q02155, HXK_PLAFA  ;
DR   Q26609, HXK_SCHMA  ;  P50506, HXK_SCHOC  ;  Q969A8, HXK_TOXGO  ;
DR   Q06204, YL446_YEAST;
//
ID   2.7.1.2
DE   Glucokinase.
AN   Glucose kinase.
CA   ATP + D-glucose = ADP + D-glucose 6-phosphate.
CC   -!- A group of enzymes found in invertebrates and microorganisms highly
CC       specific for glucose.
PR   PROSITE; PDOC00370;
PR   PROSITE; PDOC00866;
DR   Q04409, EMI2_YEAST ;  Q9GTW9, GLK1_TRIVA ;  Q9GTW8, GLK2_TRIVA ;
DR   B9J6R6, GLK_AGRRK  ;  Q8UIV7, GLK_AGRT5  ;  B9JYQ5, GLK_AGRVS  ;
DR   Q3MEM9, GLK_ANAVT  ;  Q5P8D4, GLK_AROAE  ;  Q9KCZ4, GLK_BACHD  ;
DR   P54495, GLK_BACSU  ;  B2SC34, GLK_BRUA1  ;  Q2YJN9, GLK_BRUA2  ;
DR   P0CB37, GLK_BRUAB  ;  Q8YDC6, GLK_BRUME  ;  Q8FV09, GLK_BRUSU  ;
DR   Q1BYA7, GLK_BURCA  ;  Q62HW8, GLK_BURMA  ;  Q3JPP0, GLK_BURP1  ;
DR   Q63RQ7, GLK_BURPS  ;  Q39IQ1, GLK_BURS3  ;  Q2SYA5, GLK_BURTA  ;
DR   Q143F8, GLK_BURXL  ;  A7H492, GLK_CAMJD  ;  B8GXA8, GLK_CAUCN  ;
DR   Q9A6N3, GLK_CAUCR  ;  B0T0C5, GLK_CAUSK  ;  Q1QZ16, GLK_CHRSD  ;
DR   Q7P1R6, GLK_CHRVO  ;  A8ADK6, GLK_CITK8  ;  Q47XU3, GLK_COLP3  ;
DR   Q46QB2, GLK_CUPPJ  ;  A7ZPJ8, GLK_ECO24  ;  B7UG97, GLK_ECO27  ;
DR   B7MH48, GLK_ECO45  ;  B7LCE0, GLK_ECO55  ;  P0A6V9, GLK_ECO57  ;
DR   B5YZU2, GLK_ECO5E  ;  B7NPS4, GLK_ECO7I  ;  B7MY46, GLK_ECO81  ;
DR   B7M6Q8, GLK_ECO8A  ;  C4ZVS5, GLK_ECOBW  ;  B1X9R0, GLK_ECODH  ;
DR   A8A2P2, GLK_ECOHS  ;  A1ADR4, GLK_ECOK1  ;  Q0TF72, GLK_ECOL5  ;
DR   Q8FFD4, GLK_ECOL6  ;  B1IX74, GLK_ECOLC  ;  P0A6V8, GLK_ECOLI  ;
DR   B7N5Y9, GLK_ECOLU  ;  B6I6T9, GLK_ECOSE  ;  B1LMI6, GLK_ECOSM  ;
DR   Q1R8X8, GLK_ECOUT  ;  C5BCK8, GLK_EDWI9  ;  A4WD05, GLK_ENT38  ;
DR   A7MP52, GLK_ENTS8  ;  Q6D7C4, GLK_ERWCT  ;  B2VE30, GLK_ERWT9  ;
DR   B7LL88, GLK_ESCF3  ;  Q2SPT0, GLK_HAHCH  ;  Q17YK6, GLK_HELAH  ;
DR   B6JMU2, GLK_HELP2  ;  Q1CSG4, GLK_HELPH  ;  Q9ZKB0, GLK_HELPJ  ;
DR   B2UUK7, GLK_HELPS  ;  O25731, GLK_HELPY  ;  B5XVU8, GLK_KLEP3  ;
DR   A6TC33, GLK_KLEP7  ;  Q2W5F9, GLK_MAGSA  ;  A1U1P2, GLK_MARAV  ;
DR   Q11CB2, GLK_MESSB  ;  Q5F8Q0, GLK_NEIG1  ;  B4RM12, GLK_NEIG2  ;
DR   A9M041, GLK_NEIM0  ;  P64253, GLK_NEIMA  ;  P64254, GLK_NEIMB  ;
DR   A1KUL0, GLK_NEIMF  ;  Q1QFN5, GLK_NITHX  ;  B2J224, GLK_NOSP7  ;
DR   P58616, GLK_NOSS1  ;  Q7N6Y0, GLK_PHOLL  ;  A6V2N1, GLK_PSEA7  ;
DR   B7V9H3, GLK_PSEA8  ;  Q02PZ9, GLK_PSEAB  ;  Q9HZ46, GLK_PSEAE  ;
DR   A1SXA4, GLK_PSYIN  ;  Q1LB18, GLK_RALME  ;  P58617, GLK_RALSO  ;
DR   B3PXK6, GLK_RHIE6  ;  Q2KDT9, GLK_RHIEC  ;  Q1MMY1, GLK_RHIL3  ;
DR   Q98DM2, GLK_RHILO  ;  B5ZWT5, GLK_RHILW  ;  Q92T27, GLK_RHIME  ;
DR   C3MBY4, GLK_RHISN  ;  Q21LZ9, GLK_SACD2  ;  B5F0D6, GLK_SALA4  ;
DR   A9MIH3, GLK_SALAR  ;  Q57LV0, GLK_SALCH  ;  B5FQA0, GLK_SALDC  ;
DR   B5R3T6, GLK_SALEP  ;  B5RCN1, GLK_SALG2  ;  B4TCD7, GLK_SALHS  ;
DR   B4SZS6, GLK_SALNS  ;  Q5PNF2, GLK_SALPA  ;  A9N432, GLK_SALPB  ;
DR   C0PZD3, GLK_SALPC  ;  B5BB85, GLK_SALPK  ;  B4TQD8, GLK_SALSV  ;
DR   P58618, GLK_SALTI  ;  Q93IM5, GLK_SALTY  ;  B2TWY5, GLK_SHIB3  ;
DR   Q31Y83, GLK_SHIBS  ;  Q32DF7, GLK_SHIDS  ;  Q0T2B1, GLK_SHIF8  ;
DR   Q83K86, GLK_SHIFL  ;  Q3YZE4, GLK_SHISS  ;  A6UEW0, GLK_SINMW  ;
DR   Q56198, GLK_STAXY  ;  P0A4E1, GLK_STRCO  ;  P0A4E2, GLK_STRLI  ;
DR   B4SRZ6, GLK_STRM5  ;  B2FL80, GLK_STRMK  ;  Q55855, GLK_SYNY3  ;
DR   C4LCT4, GLK_TOLAT  ;  Q8PKU2, GLK_XANAC  ;  Q3BTE6, GLK_XANC5  ;
DR   Q4UV84, GLK_XANC8  ;  B0RSF9, GLK_XANCB  ;  Q8P8U7, GLK_XANCP  ;
DR   Q2P3D0, GLK_XANOM  ;  Q5H0F2, GLK_XANOR  ;  B2I7Q9, GLK_XYLF2  ;
DR   Q9PEG4, GLK_XYLFA  ;  B0U1J8, GLK_XYLFM  ;  Q87EG6, GLK_XYLFT  ;
DR   A1JLD7, GLK_YERE8  ;  A7FGD3, GLK_YERP3  ;  Q1C5Z1, GLK_YERPA  ;
DR   B2K906, GLK_YERPB  ;  P58619, GLK_YERPE  ;  A9QZG0, GLK_YERPG  ;
DR   Q1CJU5, GLK_YERPN  ;  A4TMF1, GLK_YERPP  ;  Q668N7, GLK_YERPS  ;
DR   B1JG01, GLK_YERPY  ;  P21908, GLK_ZYMMO  ;  P82680, GLMK_PREBR ;
DR   P35557, HXK4_HUMAN ;  P52792, HXK4_MOUSE ;  P17712, HXK4_RAT   ;
DR   Q92407, HXKG_ASPNG ;  Q6CUZ3, HXKG_KLULA ;  P17709, HXKG_YEAST ;
//
ID   2.7.1.3
DE   Ketohexokinase.
AN   Hepatic fructokinase.
CA   ATP + D-fructose = ADP + D-fructose 1-phosphate.
CC   -!- D-sorbose, D-agatose and 5-dehydro-D-fructose also act as acceptors.
DR   P50053, KHK_HUMAN  ;  P97328, KHK_MOUSE  ;  Q5RD71, KHK_PONAB  ;
DR   Q02974, KHK_RAT    ;
//
ID   2.7.1.4
DE   Fructokinase.
AN   D-fructokinase.
CA   ATP + D-fructose = ADP + D-fructose 6-phosphate.
PR   PROSITE; PDOC00504;
PR   PROSITE; PDOC00866;
DR   P23917, MAK_ECOLI  ;  Q9SID0, SCRK1_ARATH;  Q6XZ79, SCRK1_MAIZE;
DR   A2WXV8, SCRK1_ORYSI;  Q0JGZ6, SCRK1_ORYSJ;  Q9LNE3, SCRK2_ARATH;
DR   Q6XZ78, SCRK2_MAIZE;  A2YQL4, SCRK2_ORYSI;  Q0J8G4, SCRK2_ORYSJ;
DR   Q7XJ81, SCRK2_SOLHA;  Q42896, SCRK2_SOLLC;  Q9LNE4, SCRK3_ARATH;
DR   Q9M1B9, SCRK4_ARATH;  O82616, SCRK5_ARATH;  O05510, SCRK_BACSU ;
DR   P40713, SCRK_ECOLX ;  Q09123, SCRK_FUSMR ;  P26420, SCRK_KLEPN ;
DR   Q09124, SCRK_LACLA ;  P82371, SCRK_LACLC ;  P43468, SCRK_PEDPE ;
DR   P42720, SCRK_RHILT ;  P24261, SCRK_SALTH ;  P26984, SCRK_SALTY ;
DR   P37829, SCRK_SOLTU ;  Q07211, SCRK_STRMU ;  P22824, SCRK_VIBAL ;
DR   Q03417, SCRK_ZYMMO ;
//
ID   2.7.1.5
DE   Rhamnulokinase.
CA   ATP + L-rhamnulose = ADP + L-rhamnulose 1-phosphate.
DR   Q5WL39, RHAAB_BACSK;  Q9KCM0, RHAB_BACHD ;  O05262, RHAB_BACSU ;
DR   Q8A1A3, RHAB_BACTN ;  A7ZUB5, RHAB_ECO24 ;  B7UNM5, RHAB_ECO27 ;
DR   B7MI36, RHAB_ECO45 ;  B7L9G0, RHAB_ECO55 ;  Q8X899, RHAB_ECO57 ;
DR   B5YZ41, RHAB_ECO5E ;  B7NUA2, RHAB_ECO7I ;  B7MQZ4, RHAB_ECO81 ;
DR   B7M6V6, RHAB_ECO8A ;  C5A072, RHAB_ECOBW ;  B1XB71, RHAB_ECODH ;
DR   A8A707, RHAB_ECOHS ;  A1AI81, RHAB_ECOK1 ;  Q0TAF9, RHAB_ECOL5 ;
DR   Q8FBD9, RHAB_ECOL6 ;  B1IVH4, RHAB_ECOLC ;  P32171, RHAB_ECOLI ;
DR   B7NFK2, RHAB_ECOLU ;  B6I4P6, RHAB_ECOSE ;  B1LMU4, RHAB_ECOSM ;
DR   Q1R415, RHAB_ECOUT ;  A4WG92, RHAB_ENT38 ;  Q838L3, RHAB_ENTFA ;
DR   Q6DA23, RHAB_ERWCT ;  B7LVD9, RHAB_ESCF3 ;  B5XZ51, RHAB_KLEP3 ;
DR   A6TGA8, RHAB_KLEP7 ;  Q88S49, RHAB_LACPL ;  Q1WRE4, RHAB_LACS1 ;
DR   Q926R0, RHAB_LISIN ;  C1L0I2, RHAB_LISMC ;  Q71VR3, RHAB_LISMF ;
DR   B8DCW1, RHAB_LISMH ;  Q8Y3I6, RHAB_LISMO ;  Q65Q24, RHAB_MANSM ;
DR   Q8ESX1, RHAB_OCEIH ;  C6DJR3, RHAB_PECCP ;  B5F0M8, RHAB_SALA4 ;
DR   Q57HG9, RHAB_SALCH ;  B5FPP4, RHAB_SALDC ;  B5QWY3, RHAB_SALEP ;
DR   B5RFC4, RHAB_SALG2 ;  B4TBY2, RHAB_SALHS ;  B4SZZ2, RHAB_SALNS ;
DR   Q5PKG3, RHAB_SALPA ;  A9MZC6, RHAB_SALPB ;  C0Q3L3, RHAB_SALPC ;
DR   B5BJG7, RHAB_SALPK ;  B4TPQ8, RHAB_SALSV ;  Q8Z2V4, RHAB_SALTI ;
DR   P27030, RHAB_SALTY ;  Q31U85, RHAB_SHIBS ;  Q0SZ94, RHAB_SHIF8 ;
DR   Q83IU3, RHAB_SHIFL ;  Q3YV72, RHAB_SHISS ;  Q1C0V9, RHAB_YERPA ;
DR   Q8ZJ02, RHAB_YERPE ;  A9QYS1, RHAB_YERPG ;  Q1CEB3, RHAB_YERPN ;
DR   A4TRT0, RHAB_YERPP ;  Q66FF3, RHAB_YERPS ;
//
ID   2.7.1.6
DE   Galactokinase.
CA   ATP + D-galactose = ADP + alpha-D-galactose 1-phosphate.
CC   -!- D-galactosamine can also act as acceptor.
PR   PROSITE; PDOC00099;
PR   PROSITE; PDOC00545;
DR   A3N103, GAL1_ACTP2 ;  B3H1M3, GAL1_ACTP7 ;  B0BPT5, GAL1_ACTPJ ;
DR   P94169, GAL1_ACTPL ;  A6VQK2, GAL1_ACTSZ ;  A0KQH8, GAL1_AERHH ;
DR   Q9KDV4, GAL1_BACHD ;  P39574, GAL1_BACSU ;  P56091, GAL1_CANAL ;
DR   P56599, GAL1_CANMA ;  O42821, GAL1_CANPA ;  A9WB97, GAL1_CHLAA ;
DR   B8GCS2, GAL1_CHLAD ;  B9LFE4, GAL1_CHLSY ;  A8AJ37, GAL1_CITK8 ;
DR   Q97EZ6, GAL1_CLOAB ;  A6M1P8, GAL1_CLOB8 ;  Q0TQU5, GAL1_CLOP1 ;
DR   Q8XKP9, GAL1_CLOPE ;  Q0ST92, GAL1_CLOPS ;  Q896X8, GAL1_CLOTE ;
DR   A7ZJD2, GAL1_ECO24 ;  B7ULN0, GAL1_ECO27 ;  B7MGL4, GAL1_ECO45 ;
DR   B7LAF8, GAL1_ECO55 ;  P0A6T4, GAL1_ECO57 ;  B5YRF5, GAL1_ECO5E ;
DR   B7NNH9, GAL1_ECO7I ;  B7MPP1, GAL1_ECO81 ;  B7M6C0, GAL1_ECO8A ;
DR   C4ZXS8, GAL1_ECOBW ;  A7ZY13, GAL1_ECOHS ;  A1A900, GAL1_ECOK1 ;
DR   Q0TJU4, GAL1_ECOL5 ;  Q8FJS1, GAL1_ECOL6 ;  B1IXX9, GAL1_ECOLC ;
DR   P0A6T3, GAL1_ECOLI ;  B7N9Z9, GAL1_ECOLU ;  B6I7R1, GAL1_ECOSE ;
DR   B1LM48, GAL1_ECOSM ;  Q1REH4, GAL1_ECOUT ;  A4W899, GAL1_ENT38 ;
DR   Q836P0, GAL1_ENTFA ;  A7MIX5, GAL1_ENTS8 ;  B2VBV2, GAL1_ERWT9 ;
DR   B7LK02, GAL1_ESCF3 ;  B1YIH8, GAL1_EXIS2 ;  Q8RHD0, GAL1_FUSNN ;
DR   A5UDQ5, GAL1_HAEIE ;  A5UHX0, GAL1_HAEIG ;  P31767, GAL1_HAEIN ;
DR   B8F7C7, GAL1_HAEPS ;  P09608, GAL1_KLULA ;  Q03PA8, GAL1_LACBA ;
DR   Q03BB8, GAL1_LACC3 ;  O84902, GAL1_LACCA ;  B3W7I5, GAL1_LACCB ;
DR   B2GEP6, GAL1_LACF3 ;  Q00052, GAL1_LACHE ;  Q9R7D7, GAL1_LACLA ;
DR   Q9S6S2, GAL1_LACLM ;  Q88SE8, GAL1_LACPL ;  A5VME2, GAL1_LACRD ;
DR   B2G9P6, GAL1_LACRJ ;  Q1WUZ4, GAL1_LACS1 ;  Q65UV5, GAL1_MANSM ;
DR   Q7U1L7, GAL1_MYCBO ;  A1KG98, GAL1_MYCBP ;  C1AKV1, GAL1_MYCBT ;
DR   A5U003, GAL1_MYCTA ;  P96910, GAL1_MYCTU ;  P57899, GAL1_PASMU ;
DR   B4F0A6, GAL1_PROMH ;  Q9HHB6, GAL1_PYRFU ;  O58107, GAL1_PYRHO ;
DR   Q5JEK8, GAL1_PYRKO ;  A7NI09, GAL1_ROSCS ;  A5UZX0, GAL1_ROSS1 ;
DR   B5F052, GAL1_SALA4 ;  A9MJI2, GAL1_SALAR ;  Q57RI3, GAL1_SALCH ;
DR   B5FP41, GAL1_SALDC ;  B5QX45, GAL1_SALEP ;  B5R741, GAL1_SALG2 ;
DR   B4TC28, GAL1_SALHS ;  B4SZH7, GAL1_SALNS ;  Q5PG77, GAL1_SALPA ;
DR   A9MTL0, GAL1_SALPB ;  C0PWW2, GAL1_SALPC ;  B5BC50, GAL1_SALPK ;
DR   B4TQR9, GAL1_SALSV ;  Q8Z8B0, GAL1_SALTI ;  P22713, GAL1_SALTY ;
DR   Q9HDU2, GAL1_SCHPO ;  A8GBA5, GAL1_SERP5 ;  B2TUY8, GAL1_SHIB3 ;
DR   Q324G2, GAL1_SHIBS ;  Q32IG8, GAL1_SHIDS ;  Q0T6Y7, GAL1_SHIF8 ;
DR   Q83M01, GAL1_SHIFL ;  Q3Z453, GAL1_SHISS ;  Q9RGS1, GAL1_STACT ;
DR   Q49ZK2, GAL1_STAS1 ;  Q9K3S8, GAL1_STRCO ;  P13227, GAL1_STRLI ;
DR   P96993, GAL1_STRMU ;  Q97NZ6, GAL1_STRPN ;  Q8DNK7, GAL1_STRR6 ;
DR   A4VT88, GAL1_STRSY ;  Q5LYY7, GAL1_STRT1 ;  Q03JS8, GAL1_STRTD ;
DR   Q9ZB10, GAL1_STRTR ;  B7IDE2, GAL1_THEAB ;  P56838, GAL1_THEMA ;
DR   O85253, GAL1_THENE ;  B9K9C8, GAL1_THENN ;  A5IMZ6, GAL1_THEP1 ;
DR   B1LCQ5, GAL1_THESQ ;  Q8R8R7, GAL1_THETN ;  C4LB24, GAL1_TOLAT ;
DR   O83433, GAL1_TREPA ;  Q9KRP1, GAL1_VIBCH ;  Q5E0M1, GAL1_VIBF1 ;
DR   B5ETC9, GAL1_VIBFM ;  A7MV01, GAL1_VIBHB ;  Q87M60, GAL1_VIBPA ;
DR   Q8DBN9, GAL1_VIBVU ;  Q7MI80, GAL1_VIBVY ;  P04385, GAL1_YEAST ;
DR   A1JRX5, GAL1_YERE8 ;  A7FKP2, GAL1_YERP3 ;  Q1C960, GAL1_YERPA ;
DR   B2K8R6, GAL1_YERPB ;  Q8ZGY3, GAL1_YERPE ;  A9R3B5, GAL1_YERPG ;
DR   Q1CFP0, GAL1_YERPN ;  A4TNR8, GAL1_YERPP ;  Q66D80, GAL1_YERPS ;
DR   B1JST8, GAL1_YERPY ;  Q9SEE5, GALK1_ARATH;  A6H768, GALK1_BOVIN;
DR   Q9GKK4, GALK1_CANFA;  P51570, GALK1_HUMAN;  Q9R0N0, GALK1_MOUSE;
DR   Q54DN6, GALK_DICDI ;
//
ID   2.7.1.7
DE   Mannokinase.
CA   ATP + D-mannose = ADP + D-mannose 6-phosphate.
DR   P82680, GLMK_PREBR ;
//
ID   2.7.1.8
DE   Glucosamine kinase.
CA   ATP + D-glucosamine = ADP + D-glucosamine phosphate.
//
ID   2.7.1.9
DE   Deleted entry.
//
ID   2.7.1.10
DE   Phosphoglucokinase.
AN   Glucose-phosphate kinase.
CA   ATP + alpha-D-glucose 1-phosphate = ADP + alpha-D-glucose 1,6-
CA   bisphosphate.
//
ID   2.7.1.11
DE   6-phosphofructokinase.
AN   Phosphofructokinase I.
AN   Phosphohexokinase.
CA   ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate.
CC   -!- D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as
CC       acceptors.
CC   -!- UTP, CTP and ITP can act as donors.
CC   -!- Not identical with EC 2.7.1.105.
PR   PROSITE; PDOC00336;
PR   PROSITE; PDOC00504;
DR   Q9M0F9, K6PF1_ARATH;  Q9HGZ1, K6PF1_ASPOR;  Q8A8R5, K6PF1_BACTN;
DR   O94201, K6PF1_CANAL;  Q8XNH2, K6PF1_CLOPE;  P0A797, K6PF1_ECO57;
DR   Q8FBD0, K6PF1_ECOL6;  P0A796, K6PF1_ECOLI;  Q03215, K6PF1_KLULA;
DR   Q8YKG3, K6PF1_NOSS1;  Q92448, K6PF1_PICPA;  P0A798, K6PF1_SHIFL;
DR   O08333, K6PF1_STRCO;  P72830, K6PF1_SYNY3;  P21777, K6PF1_THET8;
DR   P59680, K6PF1_YARLI;  P16861, K6PF1_YEAST;  Q9FIK0, K6PF2_ARATH;
DR   Q9HGZ0, K6PF2_ASPOR;  Q8A624, K6PF2_BACTN;  O94200, K6PF2_CANAL;
DR   Q8XL57, K6PF2_CLOPE;  P06999, K6PF2_ECOLI;  Q03216, K6PF2_KLULA;
DR   Q8YVR1, K6PF2_NOSS1;  Q9L1L8, K6PF2_STRCO;  Q55988, K6PF2_SYNY3;
DR   P21778, K6PF2_THET8;  P16862, K6PF2_YEAST;  Q94AA4, K6PF3_ARATH;
DR   Q8A2E9, K6PF3_BACTN;  Q9FC99, K6PF3_STRCO;  Q9FKG3, K6PF4_ARATH;
DR   Q8VYN6, K6PF5_ARATH;  Q9M076, K6PF6_ARATH;  Q9C5J7, K6PF7_ARATH;
DR   A3N1C8, K6PF_ACTP2 ;  B3GY11, K6PF_ACTP7 ;  B0BQ64, K6PF_ACTPJ ;
DR   A6VM63, K6PF_ACTSZ ;  B6EMS4, K6PF_ALISL ;  A6TVD3, K6PF_ALKMQ ;
DR   A8MLY0, K6PF_ALKOO ;  Q3M8N2, K6PF_ANAVT ;  B7GGT1, K6PF_ANOFW ;
DR   O67605, K6PF_AQUAE ;  Q4W9B8, K6PF_ASPFU ;  P78985, K6PF_ASPNG ;
DR   A7Z7K6, K6PF_BACA2 ;  C3PAI8, K6PF_BACAA ;  C3L8X8, K6PF_BACAC ;
DR   A0RJJ6, K6PF_BACAH ;  Q81KZ0, K6PF_BACAN ;  B7JRX2, K6PF_BACC0 ;
DR   Q72ZD8, K6PF_BACC1 ;  B7IJZ8, K6PF_BACC2 ;  C1EUU3, K6PF_BACC3 ;
DR   B7HFB3, K6PF_BACC4 ;  B7HRN9, K6PF_BACC7 ;  Q4MVY3, K6PF_BACCE ;
DR   A7GTP4, K6PF_BACCN ;  B9J099, K6PF_BACCQ ;  Q817F3, K6PF_BACCR ;
DR   Q633J8, K6PF_BACCZ ;  Q9K843, K6PF_BACHD ;  Q6HCT3, K6PF_BACHK ;
DR   Q65G82, K6PF_BACLD ;  Q59214, K6PF_BACMC ;  A8FG55, K6PF_BACP2 ;
DR   Q5WEF6, K6PF_BACSK ;  O34529, K6PF_BACSU ;  A9VJR1, K6PF_BACWK ;
DR   Q1LTT2, K6PF_BAUCH ;  Q7VRK9, K6PF_BLOFL ;  Q0IIG5, K6PF_BOVIN ;
DR   C0Z7W7, K6PF_BREBN ;  B8D996, K6PF_BUCA5 ;  P57391, K6PF_BUCAI ;
DR   Q8K9N0, K6PF_BUCAP ;  B8D7J8, K6PF_BUCAT ;  P59563, K6PF_BUCBP ;
DR   Q057P0, K6PF_BUCCC ;  Q27483, K6PF_CAEEL ;  Q27543, K6PF_CALFI ;
DR   P52784, K6PF_CANFA ;  A9WCU2, K6PF_CHLAA ;  B8GAA4, K6PF_CHLAD ;
DR   B9LHK4, K6PF_CHLSY ;  A8AL13, K6PF_CITK8 ;  O08308, K6PF_CLOAB ;
DR   A7FYW7, K6PF_CLOB1 ;  C3KV06, K6PF_CLOB6 ;  B2UZX8, K6PF_CLOBA ;
DR   B2TQR6, K6PF_CLOBB ;  A5I798, K6PF_CLOBH ;  C1FM55, K6PF_CLOBJ ;
DR   B1IFV9, K6PF_CLOBK ;  A7GIW9, K6PF_CLOBL ;  B1L266, K6PF_CLOBM ;
DR   Q180P4, K6PF_CLOD6 ;  A0PYC8, K6PF_CLONN ;  Q890Z2, K6PF_CLOTE ;
DR   Q8RQN5, K6PF_COREF ;  Q8NR14, K6PF_CORGL ;  Q83EH9, K6PF_COXBU ;
DR   Q11RE2, K6PF_CYTH3 ;  Q9RWN1, K6PF_DEIRA ;  P90521, K6PF_DICDI ;
DR   P52034, K6PF_DROME ;  A7ZUC9, K6PF_ECO24 ;  B7UNN6, K6PF_ECO27 ;
DR   B7MI48, K6PF_ECO45 ;  B7LA13, K6PF_ECO55 ;  B5YZ53, K6PF_ECO5E ;
DR   B7NU91, K6PF_ECO7I ;  B7N2Q7, K6PF_ECO81 ;  B7M6W7, K6PF_ECO8A ;
DR   C5A083, K6PF_ECOBW ;  B1XB82, K6PF_ECODH ;  A8A720, K6PF_ECOHS ;
DR   Q0TAE8, K6PF_ECOL5 ;  B1IVG3, K6PF_ECOLC ;  B7NFL3, K6PF_ECOLU ;
DR   B6I4Q8, K6PF_ECOSE ;  B1LNL9, K6PF_ECOSM ;  C5BC26, K6PF_EDWI9 ;
DR   A4WG81, K6PF_ENT38 ;  Q9Z6C3, K6PF_ENTCL ;  Q836R3, K6PF_ENTFA ;
DR   A7MQ83, K6PF_ENTS8 ;  Q6CZ46, K6PF_ERWCT ;  B2VF62, K6PF_ERWT9 ;
DR   B7LVC9, K6PF_ESCF3 ;  B0S230, K6PF_FINM2 ;  Q8RG98, K6PF_FUSNN ;
DR   Q5KWB1, K6PF_GEOKA ;  P00512, K6PF_GEOSE ;  C5D663, K6PF_GEOSW ;
DR   Q27665, K6PF_HAECO ;  Q8GNC1, K6PF_HAEDU ;  Q4QLS8, K6PF_HAEI8 ;
DR   A5UD89, K6PF_HAEIE ;  P43863, K6PF_HAEIN ;  B8F8G9, K6PF_HAEPS ;
DR   Q0I267, K6PF_HAES1 ;  B0UW05, K6PF_HAES2 ;  B8D1K5, K6PF_HALOH ;
DR   C4K7E1, K6PF_HAMD5 ;  Q867C9, K6PF_HORSE ;  P08237, K6PF_HUMAN ;
DR   B5XZ40, K6PF_KLEP3 ;  A6TGB8, K6PF_KLEP7 ;  Q5FKG6, K6PF_LACAC ;
DR   Q039I0, K6PF_LACC3 ;  B3WE64, K6PF_LACCB ;  P80019, K6PF_LACDE ;
DR   Q043V2, K6PF_LACGA ;  A8YV22, K6PF_LACH4 ;  Q74JM8, K6PF_LACJO ;
DR   Q07636, K6PF_LACLA ;  A2RKA2, K6PF_LACLM ;  Q02YK5, K6PF_LACLS ;
DR   Q88VY1, K6PF_LACPL ;  Q1WTT3, K6PF_LACS1 ;  Q92BE4, K6PF_LISIN ;
DR   C1KVL8, K6PF_LISMC ;  Q71Z96, K6PF_LISMF ;  B8DHH7, K6PF_LISMH ;
DR   Q8Y6W0, K6PF_LISMO ;  A0AJ20, K6PF_LISW6 ;  Q93LR4, K6PF_LYSSH ;
DR   B9E7A4, K6PF_MACCJ ;  Q60HD9, K6PF_MACFA ;  Q65VM6, K6PF_MANSM ;
DR   P47857, K6PF_MOUSE ;  P65691, K6PF_MYCBO ;  Q2SSQ6, K6PF_MYCCT ;
DR   P47457, K6PF_MYCGE ;  Q601D3, K6PF_MYCH2 ;  Q4A8Q3, K6PF_MYCH7 ;
DR   Q4AAM2, K6PF_MYCHJ ;  O33106, K6PF_MYCLE ;  Q6KHX0, K6PF_MYCMO ;
DR   Q8EVH2, K6PF_MYCPE ;  P75476, K6PF_MYCPN ;  Q98PW8, K6PF_MYCPU ;
DR   P65690, K6PF_MYCTU ;  B2A6Y0, K6PF_NATTJ ;  Q8EPD6, K6PF_OCEIH ;
DR   Q9CPH2, K6PF_PASMU ;  C6DHK2, K6PF_PECCP ;  Q03F74, K6PF_PEDPA ;
DR   C0QQX4, K6PF_PERMH ;  Q6LVK2, K6PF_PHOPR ;  Q2HYU2, K6PF_PIG   ;
DR   Q5RAG9, K6PF_PONAB ;  P00511, K6PF_RABIT ;  P47858, K6PF_RAT   ;
DR   B5F0P6, K6PF_SALA4 ;  A9MI50, K6PF_SALAR ;  Q57HF3, K6PF_SALCH ;
DR   B5FPR2, K6PF_SALDC ;  B5QWZ5, K6PF_SALEP ;  B5RFA9, K6PF_SALG2 ;
DR   B4TCK0, K6PF_SALHS ;  B4T049, K6PF_SALNS ;  Q5PIR6, K6PF_SALPA ;
DR   A9MZE7, K6PF_SALPB ;  C0Q414, K6PF_SALPC ;  B5BJI2, K6PF_SALPK ;
DR   B4TPS6, K6PF_SALSV ;  P65693, K6PF_SALTI ;  P65692, K6PF_SALTY ;
DR   Q27778, K6PF_SCHMA ;  O42938, K6PF_SCHPO ;  A8GLB0, K6PF_SERP5 ;
DR   B2TVQ8, K6PF_SHIB3 ;  Q31U74, K6PF_SHIBS ;  Q32A80, K6PF_SHIDS ;
DR   Q3YV62, K6PF_SHISS ;  Q2NQX2, K6PF_SODGM ;  P20275, K6PF_SPICI ;
DR   A6U2G5, K6PF_STAA2 ;  A5ITM2, K6PF_STAA9 ;  Q2YTE2, K6PF_STAAB ;
DR   Q5HF75, K6PF_STAAC ;  A6QHN3, K6PF_STAAE ;  P65694, K6PF_STAAM ;
DR   P99165, K6PF_STAAN ;  Q6GG08, K6PF_STAAR ;  Q6G8M8, K6PF_STAAS ;
DR   A8Z2L4, K6PF_STAAT ;  P65695, K6PF_STAAW ;  B9DN94, K6PF_STACT ;
DR   Q5HNK6, K6PF_STAEQ ;  Q8CS68, K6PF_STAES ;  Q3K1E6, K6PF_STRA1 ;
DR   P65696, K6PF_STRA3 ;  P65697, K6PF_STRA5 ;  C0M8V6, K6PF_STRE4 ;
DR   B4U2M2, K6PF_STREM ;  A8AXW1, K6PF_STRGC ;  Q8DTX6, K6PF_STRMU ;
DR   Q99ZD0, K6PF_STRP1 ;  Q04L24, K6PF_STRP2 ;  P0DD02, K6PF_STRP3 ;
DR   B5E3Z8, K6PF_STRP4 ;  Q5XBV2, K6PF_STRP6 ;  C1C6M8, K6PF_STRP7 ;
DR   Q8P0S6, K6PF_STRP8 ;  Q1JBF7, K6PF_STRPB ;  Q1JLD9, K6PF_STRPC ;
DR   Q1JGH6, K6PF_STRPD ;  Q1J694, K6PF_STRPF ;  A2RE65, K6PF_STRPG ;
DR   B1IB66, K6PF_STRPI ;  B8ZNU0, K6PF_STRPJ ;  Q48T86, K6PF_STRPM ;
DR   Q97RC6, K6PF_STRPN ;  P0DD03, K6PF_STRPQ ;  B2IP53, K6PF_STRPS ;
DR   B5XLV6, K6PF_STRPZ ;  Q8DQ85, K6PF_STRR6 ;  C0MGJ9, K6PF_STRS7 ;
DR   A3CM69, K6PF_STRSV ;  A4VTS0, K6PF_STRSY ;  Q03KB7, K6PF_STRTD ;
DR   Q9L9E3, K6PF_STRTR ;  B9DSA4, K6PF_STRU0 ;  C1CDP4, K6PF_STRZJ ;
DR   C1CJY4, K6PF_STRZP ;  C1CRZ7, K6PF_STRZT ;  Q30T53, K6PF_SULDN ;
DR   A6QAB4, K6PF_SULNB ;  B2V7W7, K6PF_SULSY ;  C5BNR1, K6PF_TERTT ;
DR   Q8DJB1, K6PF_THEEB ;  Q9WY52, K6PF_THEMA ;  B9K6R9, K6PF_THENN ;
DR   A5IKL2, K6PF_THEP1 ;  B0K7U7, K6PF_THEP3 ;  B0K6L2, K6PF_THEPX ;
DR   B1L9U3, K6PF_THESQ ;  Q72H98, K6PF_THET2 ;  Q8R914, K6PF_THETN ;
DR   C4LEQ5, K6PF_TOLAT ;  Q9PQV8, K6PF_UREPA ;  Q9KNP2, K6PF_VIBCH ;
DR   Q5E2B1, K6PF_VIBF1 ;  B5FBT1, K6PF_VIBFM ;  A7MX59, K6PF_VIBHB ;
DR   Q87KX0, K6PF_VIBPA ;  Q8DCY1, K6PF_VIBVU ;  Q7MGW6, K6PF_VIBVY ;
DR   Q7M9C2, K6PF_WOLSU ;  A1JHZ3, K6PF_YERE8 ;  A7FCW1, K6PF_YERP3 ;
DR   Q1C297, K6PF_YERPA ;  B2JZA3, K6PF_YERPB ;  Q8ZJL6, K6PF_YERPE ;
DR   A9R6A3, K6PF_YERPG ;  Q1CD33, K6PF_YERPN ;  A4TSA7, K6PF_YERPP ;
DR   Q66GA8, K6PF_YERPS ;  B1JQU4, K6PF_YERPY ;  A1A4J1, K6PL_BOVIN ;
DR   P17858, K6PL_HUMAN ;  P12382, K6PL_MOUSE ;  Q5R7V5, K6PL_PONAB ;
DR   P30835, K6PL_RAT   ;  Q01813, K6PP_HUMAN ;  Q9WUA3, K6PP_MOUSE ;
DR   Q5R636, K6PP_PONAB ;  P47859, K6PP_RABIT ;  P47860, K6PP_RAT   ;
//
ID   2.7.1.12
DE   Gluconokinase.
AN   Gluconate kinase.
CA   ATP + D-gluconate = ADP + 6-phospho-D-gluconate.
PR   PROSITE; PDOC00408;
DR   P46834, GNTK_BACLI ;  P12011, GNTK_BACSU ;  Q54PI5, GNTK_DICDI ;
DR   P46859, GNTK_ECOLI ;  Q5T6J7, GNTK_HUMAN ;  Q8R0J8, GNTK_MOUSE ;
DR   Q32PY9, GNTK_RAT   ;  Q10242, GNTK_SCHPO ;  B0BML1, GNTK_XENTR ;
DR   Q03786, GNTK_YEAST ;  P39208, IDNK_ECOLI ;
//
ID   2.7.1.13
DE   Dehydrogluconokinase.
AN   Ketogluconokinase.
CA   ATP + 2-dehydro-D-gluconate = ADP + 6-phospho-2-dehydro-D-gluconate.
//
ID   2.7.1.14
DE   Sedoheptulokinase.
AN   Heptulokinase.
CA   ATP + sedoheptulose = ADP + sedoheptulose 7-phosphate.
DR   Q9UHJ6, SHPK_HUMAN ;  Q9D5J6, SHPK_MOUSE ;
//
ID   2.7.1.15
DE   Ribokinase.
CA   ATP + D-ribose = ADP + D-ribose 5-phosphate.
CC   -!- 2-deoxy-D-ribose can also act as acceptor.
PR   PROSITE; PDOC00504;
DR   Q9K6K1, RBSK_BACHD ;  P36945, RBSK_BACSU ;  Q54UQ4, RBSK_DICDI ;
DR   P0A9J7, RBSK_ECO57 ;  P0A9J6, RBSK_ECOLI ;  P44331, RBSK_HAEIN ;
DR   Q9H477, RBSK_HUMAN ;  Q9CF42, RBSK_LACLA ;  P83534, RBSK_LACSN ;
DR   Q8R1Q9, RBSK_MOUSE ;  O60116, RBSK_SCHPO ;  P25332, RBSK_YEAST ;
//
ID   2.7.1.16
DE   Ribulokinase.
AN   L-ribulokinase.
CA   ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate.
CC   -!- Ribitol and L-arabinitol can also act as acceptors.
DR   Q49ZR6, ARAB1_STAS1;  Q49V87, ARAB2_STAS1;  B7GGV9, ARAB_ANOFW ;
DR   Q9KBQ3, ARAB_BACHD ;  Q65GC1, ARAB_BACLD ;  Q5WL06, ARAB_BACSK ;
DR   P94524, ARAB_BACSU ;  A8ALN9, ARAB_CITK8 ;  A7ZHF4, ARAB_ECO24 ;
DR   B7UIA9, ARAB_ECO27 ;  B7MAI6, ARAB_ECO45 ;  B7L4I4, ARAB_ECO55 ;
DR   P58541, ARAB_ECO57 ;  B5YZ99, ARAB_ECO5E ;  B7NHG9, ARAB_ECO7I ;
DR   B7MNS0, ARAB_ECO81 ;  B7M0F8, ARAB_ECO8A ;  C4ZPY6, ARAB_ECOBW ;
DR   A7ZW13, ARAB_ECOHS ;  A1A7B0, ARAB_ECOK1 ;  Q0TLS7, ARAB_ECOL5 ;
DR   Q8FL88, ARAB_ECOL6 ;  B1IRB5, ARAB_ECOLC ;  P08204, ARAB_ECOLI ;
DR   B7N7T7, ARAB_ECOLU ;  B6HZ43, ARAB_ECOSE ;  B1LFZ7, ARAB_ECOSM ;
DR   Q1RGD6, ARAB_ECOUT ;  A4W6G7, ARAB_ENT38 ;  Q6D4W6, ARAB_ERWCT ;
DR   B2VEQ9, ARAB_ERWT9 ;  B7LVT4, ARAB_ESCF3 ;  Q5KYP6, ARAB_GEOKA ;
DR   Q9S468, ARAB_GEOSE ;  A4IPA2, ARAB_GEOTN ;  B5Y1Y0, ARAB_KLEP3 ;
DR   A6T4K1, ARAB_KLEP7 ;  Q9LBQ3, ARAB_MYCSM ;  C6DH20, ARAB_PECCP ;
DR   B5F784, ARAB_SALA4 ;  A9MQF0, ARAB_SALAR ;  B5FI46, ARAB_SALDC ;
DR   B5R1U0, ARAB_SALEP ;  B5RGD4, ARAB_SALG2 ;  B4TJ60, ARAB_SALHS ;
DR   B4SU24, ARAB_SALNS ;  Q5PDF1, ARAB_SALPA ;  A9MYN9, ARAB_SALPB ;
DR   B5BL44, ARAB_SALPK ;  B4TWU9, ARAB_SALSV ;  P58542, ARAB_SALTI ;
DR   P06188, ARAB_SALTY ;  A8GE05, ARAB_SERP5 ;  B2U269, ARAB_SHIB3 ;
DR   Q326H2, ARAB_SHIBS ;  Q32K30, ARAB_SHIDS ;  Q0T8D4, ARAB_SHIF8 ;
DR   Q83MG5, ARAB_SHIFL ;  Q3Z5U8, ARAB_SHISS ;  A7WYY2, ARAB_STAA1 ;
DR   Q2FJ88, ARAB_STAA3 ;  Q2G0M6, ARAB_STAA8 ;  Q2YSA9, ARAB_STAAB ;
DR   Q5HIC3, ARAB_STAAC ;  A6QEK4, ARAB_STAAE ;  P63549, ARAB_STAAM ;
DR   P63550, ARAB_STAAN ;  Q6GJB6, ARAB_STAAR ;  Q6GBT5, ARAB_STAAS ;
DR   Q8NXY1, ARAB_STAAW ;  Q5HLQ6, ARAB_STAEQ ;  Q8CRC6, ARAB_STAES ;
DR   Q87FK5, ARAB_VIBPA ;  Q1C7J2, ARAB_YERPA ;  P58543, ARAB_YERPE ;
DR   Q1CIX8, ARAB_YERPN ;  Q66AF7, ARAB_YERPS ;
//
ID   2.7.1.17
DE   Xylulokinase.
AN   Xylulose kinase.
CA   ATP + D-xylulose = ADP + D-xylulose 5-phosphate.
PR   PROSITE; PDOC00408;
DR   C5FSW4, XKS1_ARTOC ;  A1CAU3, XKS1_ASPCL ;  B0Y4D5, XKS1_ASPFC ;
DR   B8NTI4, XKS1_ASPFN ;  Q4WUV8, XKS1_ASPFU ;  A2QMS4, XKS1_ASPNC ;
DR   Q8X167, XKS1_ASPNG ;  Q2U3V4, XKS1_ASPOR ;  Q0CIL2, XKS1_ASPTN ;
DR   Q5ASE0, XKS1_EMENI ;  A1DEK3, XKS1_NEOFI ;  Q9C0U6, XKS1_SCHPO ;
DR   P42826, XKS1_YEAST ;  P12867, XYLB_ACTMI ;  P54271, XYLB_AMPSP ;
DR   P26909, XYLB_ARTS7 ;  P39211, XYLB_BACSU ;  Q3SYZ6, XYLB_BOVIN ;
DR   P09099, XYLB_ECOLI ;  P44401, XYLB_HAEIN ;  O75191, XYLB_HUMAN ;
DR   P29444, XYLB_KLEPN ;  P35850, XYLB_LACBR ;  Q9CFG8, XYLB_LACLA ;
DR   P21939, XYLB_LACPE ;  Q3TNA1, XYLB_MOUSE ;  Q5R830, XYLB_PONAB ;
DR   Q3MIF4, XYLB_RAT   ;  P27155, XYLB_STAXY ;  Q9RK00, XYLB_STRCO ;
DR   P27156, XYLB_STRRU ;
//
ID   2.7.1.18
DE   Phosphoribokinase.
CA   ATP + D-ribose 5-phosphate = ADP + D-ribose 1,5-bisphosphate.
//
ID   2.7.1.19
DE   Phosphoribulokinase.
AN   Phosphopentokinase.
CA   ATP + D-ribulose 5-phosphate = ADP + D-ribulose 1,5-bisphosphate.
PR   PROSITE; PDOC00490;
DR   P19924, KPPR1_CUPNH;  P12033, KPPR1_RHOSH;  P25933, KPPR1_SELMI;
DR   P19923, KPPR2_CUPNH;  P23010, KPPR2_RHOSH;  P25934, KPPR2_SELMI;
DR   P25697, KPPR_ARATH ;  P19824, KPPR_CHLRE ;  P0AEX5, KPPR_ECOLI ;
DR   P27774, KPPR_MESCR ;  P37100, KPPR_NITVU ;  P81664, KPPR_PINPS ;
DR   P58347, KPPR_RHIME ;  P0AEX6, KPPR_SHIFL ;  P56887, KPPR_SINMW ;
DR   P09559, KPPR_SPIOL ;  P37101, KPPR_SYNY3 ;  P85112, KPPR_VITSX ;
DR   P26302, KPPR_WHEAT ;  P23015, KPPR_XANFL ;
//
ID   2.7.1.20
DE   Adenosine kinase.
CA   ATP + adenosine = ADP + AMP.
CC   -!- 2-aminoadenosine can also act as acceptor.
PR   PROSITE; PDOC00504;
DR   Q9SF85, ADK1_ARATH ;  Q9LZG0, ADK2_ARATH ;  P55262, ADK_CRIGR  ;
DR   Q54MB5, ADK_DICDI  ;  P55263, ADK_HUMAN  ;  P55264, ADK_MOUSE  ;
DR   O49923, ADK_PHYPA  ;  Q64640, ADK_RAT    ;  O93919, ADK_SCHCO  ;
DR   P78825, ADK_SCHPO  ;  Q9TVW2, ADK_TOXGO  ;  P47143, ADK_YEAST  ;
DR   P83736, ADOK_MYCBO ;  A5U4N0, ADOK_MYCTA ;  P83734, ADOK_MYCTU ;
//
ID   2.7.1.21
DE   Thymidine kinase.
CA   ATP + thymidine = ADP + thymidine 5'-phosphate.
CC   -!- Deoxyuridine can also act as acceptor.
CC   -!- dGTP can also act as donor.
CC   -!- The deoxypyrimidine kinase complex induced by Herpes simplex virus
CC       catalyzes this reaction as well as those of EC 2.7.1.114,
CC       EC 2.7.1.118, and EC 2.7.4.9.
CC   -!- Formerly EC 2.7.1.75.
PR   PROSITE; PDOC00524;
DR   Q7CXF9, KITH_AGRT5 ;  P33802, KITH_AHV1W ;  O36371, KITH_ALHV1 ;
DR   P28852, KITH_AMEPV ;  B7GMH4, KITH_ANOFW ;  P18555, KITH_ASFB7 ;
DR   P0C8I3, KITH_ASFK5 ;  P0C8I4, KITH_ASFM2 ;  P0C8I5, KITH_ASFP4 ;
DR   P0C8I6, KITH_ASFWA ;  Q2NIM1, KITH_AYWBP ;  A7Z9S5, KITH_BACA2 ;
DR   C3P292, KITH_BACAA ;  C3LFK4, KITH_BACAC ;  A0RLB6, KITH_BACAH ;
DR   Q81JX0, KITH_BACAN ;  B7JHF2, KITH_BACC0 ;  Q72XC1, KITH_BACC1 ;
DR   B7IQY3, KITH_BACC2 ;  C1F0Q7, KITH_BACC3 ;  B7HFM8, KITH_BACC4 ;
DR   B7HY90, KITH_BACC7 ;  A7GV80, KITH_BACCN ;  B9IRW3, KITH_BACCQ ;
DR   Q814U0, KITH_BACCR ;  Q630R8, KITH_BACCZ ;  Q5LHP5, KITH_BACFN ;
DR   Q64YL9, KITH_BACFR ;  Q9K6F0, KITH_BACHD ;  Q6HAV3, KITH_BACHK ;
DR   Q65DU6, KITH_BACLD ;  O52951, KITH_BACNA ;  A8FID5, KITH_BACP2 ;
DR   Q5WB52, KITH_BACSK ;  Q03221, KITH_BACSU ;  Q8A5G4, KITH_BACTN ;
DR   A6L1E7, KITH_BACV8 ;  A9VSC8, KITH_BACWK ;  Q6MHW4, KITH_BDEBA ;
DR   P24096, KITH_BHV16 ;  P24424, KITH_BHV1Q ;  P22649, KITH_BHV2H ;
DR   P36226, KITH_BHV5  ;  Q7VQZ6, KITH_BLOFL ;  Q492N1, KITH_BLOPB ;
DR   A5D7R8, KITH_BOVIN ;  P13300, KITH_BPT4  ;  Q05879, KITH_CBEPV ;
DR   Q05880, KITH_CFEPV ;  P04047, KITH_CHICK ;  A9WGI6, KITH_CHLAA ;
DR   B8G6Y1, KITH_CHLAD ;  B9LJ65, KITH_CHLSY ;  Q7NVK0, KITH_CHRVO ;
DR   Q97F65, KITH_CLOAB ;  A7FQF9, KITH_CLOB1 ;  C3KYH2, KITH_CLOB6 ;
DR   A5HY32, KITH_CLOBH ;  C1FQ94, KITH_CLOBJ ;  B1IE18, KITH_CLOBK ;
DR   A7G9N9, KITH_CLOBL ;  B1KSQ8, KITH_CLOBM ;  Q898Y8, KITH_CLOTE ;
DR   Q483R5, KITH_COLP3 ;  B5Y8S5, KITH_COPPD ;  Q83A42, KITH_COXBU ;
DR   P09768, KITH_CRIGR ;  C1D0Z6, KITH_DEIDV ;  Q9RSY5, KITH_DEIRA ;
DR   Q27564, KITH_DICDI ;  B5YDB0, KITH_DICT6 ;  B8E001, KITH_DICTD ;
DR   Q1HVD1, KITH_EBVA8 ;  P03177, KITH_EBVB9 ;  Q3KSQ2, KITH_EBVG  ;
DR   P0A3L9, KITH_ECO57 ;  Q8FHX4, KITH_ECOL6 ;  P23331, KITH_ECOLI ;
DR   P69186, KITH_EHV1  ;  P69185, KITH_EHV1B ;  Q66624, KITH_EHV2  ;
DR   P24425, KITH_EHV4  ;  Q18LE8, KITH_ELHVK ;  O96720, KITH_ENCCU ;
DR   Q831F5, KITH_ENTFA ;  Q6D4R3, KITH_ERWCT ;  P13159, KITH_FHV1  ;
DR   P10052, KITH_FOWPN ;  Q2A3U3, KITH_FRATH ;  Q5NH50, KITH_FRATT ;
DR   Q9E6P5, KITH_GAHVM ;  P17653, KITH_GAHVR ;  Q5KUH1, KITH_GEOKA ;
DR   C5D9N8, KITH_GEOSW ;  A4ITL0, KITH_GEOTN ;  Q7VLH2, KITH_HAEDU ;
DR   Q4QN19, KITH_HAEI8 ;  P44309, KITH_HAEIN ;  B0R5S5, KITH_HALS3 ;
DR   Q9HPQ9, KITH_HALSA ;  Q18J88, KITH_HALWD ;  Q9QNF7, KITH_HHV1  ;
DR   P03176, KITH_HHV11 ;  P06478, KITH_HHV1C ;  P08333, KITH_HHV1E ;
DR   P17402, KITH_HHV1K ;  P06479, KITH_HHV1S ;  P04407, KITH_HHV23 ;
DR   P89446, KITH_HHV2H ;  P04183, KITH_HUMAN ;  P28855, KITH_ICHVA ;
DR   Q5QWC7, KITH_IDILO ;  P23983, KITH_ILTVT ;  Q28M21, KITH_JANSC ;
DR   Q5FKZ1, KITH_LACAC ;  Q74K26, KITH_LACJO ;  Q9CHX5, KITH_LACLA ;
DR   Q88UT1, KITH_LACPL ;  Q38WJ3, KITH_LACSS ;  Q5X7B5, KITH_LEGPA ;
DR   Q5ZXU5, KITH_LEGPH ;  Q5WYR3, KITH_LEGPL ;  Q927U9, KITH_LISIN ;
DR   Q71WN4, KITH_LISMF ;  Q8Y4A7, KITH_LISMO ;  B9E8G2, KITH_MACCJ ;
DR   Q65RN9, KITH_MANSM ;  P25987, KITH_MEHV1 ;  P13157, KITH_MEHVF ;
DR   Q6F0I2, KITH_MESFL ;  Q5UP25, KITH_MIMIV ;  P04363, KITH_MONPV ;
DR   P04184, KITH_MOUSE ;  B3PM40, KITH_MYCA5 ;  Q2SSX9, KITH_MYCCT ;
DR   Q8RLE0, KITH_MYCGA ;  P47280, KITH_MYCGE ;  Q5ZZT0, KITH_MYCH2 ;
DR   Q4A7B8, KITH_MYCH7 ;  Q4A977, KITH_MYCHJ ;  Q6KH30, KITH_MYCMO ;
DR   Q8VVL0, KITH_MYCMS ;  Q8EU99, KITH_MYCPE ;  P75070, KITH_MYCPN ;
DR   Q9Q8N6, KITH_MYXVL ;  P28851, KITH_MYXVU ;  Q2G5F0, KITH_NOVAD ;
DR   Q8EM59, KITH_OCEIH ;  Q6YRB1, KITH_ONYPE ;  O81263, KITH_ORYSJ ;
DR   P57926, KITH_PASMU ;  Q7N457, KITH_PHOLL ;  Q6LT81, KITH_PHOPR ;
DR   B2RJJ6, KITH_PORG3 ;  Q7MVV7, KITH_PORGI ;  Q6A8W6, KITH_PROAC ;
DR   Q3IBU5, KITH_PSEHT ;  Q6UDK9, KITH_PSHV1 ;  Q8ZV53, KITH_PYRAE ;
DR   Q5JGT7, KITH_PYRKO ;  Q90029, KITH_RACVI ;  P27158, KITH_RAT   ;
DR   P07605, KITH_RFVKA ;  Q2K5N6, KITH_RHIEC ;  Q98HR4, KITH_RHILO ;
DR   Q92N38, KITH_RHIME ;  Q7UFR1, KITH_RHOBA ;  Q21Q74, KITH_RHOFD ;
DR   Q9ZIG2, KITH_RHOSI ;  A7NI79, KITH_ROSCS ;  A5UZV5, KITH_ROSS1 ;
DR   Q57NR0, KITH_SALCH ;  Q5PCT4, KITH_SALPA ;  Q2RZH4, KITH_SALRD ;
DR   Q8XFQ8, KITH_SALTI ;  Q7CQF3, KITH_SALTY ;  Q8ECK0, KITH_SHEON ;
DR   P16600, KITH_SHEVK ;  Q31ZS8, KITH_SHIBS ;  Q32GW8, KITH_SHIDS ;
DR   P0A3M0, KITH_SHIFL ;  Q3Z0V3, KITH_SHISS ;  P04408, KITH_SHV1  ;
DR   P21293, KITH_SHV21 ;  Q5LUY8, KITH_SILPO ;  Q2FF09, KITH_STAA3 ;
DR   Q2YUN4, KITH_STAAB ;  Q5HE81, KITH_STAAC ;  P65230, KITH_STAAM ;
DR   P65231, KITH_STAAN ;  Q6GEV6, KITH_STAAR ;  Q6G7J1, KITH_STAAS ;
DR   Q8NVG5, KITH_STAAW ;  Q5HMA3, KITH_STAEQ ;  Q8CRM9, KITH_STAES ;
DR   Q4L800, KITH_STAHJ ;  Q49Z66, KITH_STAS1 ;  Q3K118, KITH_STRA1 ;
DR   Q8E5C2, KITH_STRA3 ;  Q8DZM3, KITH_STRA5 ;  Q82KI9, KITH_STRAW ;
DR   O50519, KITH_STRCO ;  P47848, KITH_STRGC ;  Q8DU63, KITH_STRMU ;
DR   Q99ZP6, KITH_STRP1 ;  P0DB96, KITH_STRP3 ;  Q5XC70, KITH_STRP6 ;
DR   Q8P126, KITH_STRP8 ;  Q48TL1, KITH_STRPM ;  Q97R22, KITH_STRPN ;
DR   P0DB97, KITH_STRPQ ;  Q8DPZ6, KITH_STRR6 ;  Q5M0B8, KITH_STRT1 ;
DR   Q5M4W5, KITH_STRT2 ;  P27363, KITH_SUHVN ;  P23335, KITH_SWPVK ;
DR   A8F7B3, KITH_THELT ;  Q9WYN2, KITH_THEMA ;  A5IK18, KITH_THEP1 ;
DR   B0K7G9, KITH_THEP3 ;  B0K1F4, KITH_THEPX ;  B1L989, KITH_THESQ ;
DR   Q8RDA1, KITH_THETN ;  B1AJN5, KITH_UREP2 ;  Q9PPP5, KITH_UREPA ;
DR   B5ZCA9, KITH_UREU1 ;  O57203, KITH_VACCA ;  P68564, KITH_VACCC ;
DR   Q9JFB7, KITH_VACCT ;  P68563, KITH_VACCW ;  P04364, KITH_VAR67 ;
DR   Q9KST9, KITH_VIBCH ;  Q5E4F2, KITH_VIBF1 ;  Q87QJ8, KITH_VIBPA ;
DR   Q8D8R2, KITH_VIBVU ;  Q7MLR4, KITH_VIBVY ;  P09250, KITH_VZVD  ;
DR   P0C0E6, KITH_VZVO  ;  Q8PEQ8, KITH_XANAC ;  Q3BM98, KITH_XANC5 ;
DR   Q4UNV0, KITH_XANC8 ;  Q8P3C8, KITH_XANCP ;  Q2P902, KITH_XANOM ;
DR   Q5H6C5, KITH_XANOR ;  Q8ZEJ1, KITH_YERPE ;  Q66AM8, KITH_YERPS ;
DR   Q90033, KITH_YMTV5 ;  Q5NQ29, KITH_ZYMMO ;  O00142, KITM_HUMAN ;
DR   Q9N0C5, KITM_MACFA ;  Q9R088, KITM_MOUSE ;
//
ID   2.7.1.22
DE   Ribosylnicotinamide kinase.
AN   Nicotinamide riboside kinase.
CA   ATP + N-ribosylnicotinamide = ADP + nicotinamide ribonucleotide.
DR   P27278, NADR_ECOLI ;  P44308, NADR_HAEIN ;  P47981, NADR_KLEPN ;
DR   P24518, NADR_SALTY ;  P62511, NRK1_ASHGO ;  Q9NWW6, NRK1_HUMAN ;
DR   Q91W63, NRK1_MOUSE ;  Q6AY91, NRK1_RAT   ;  Q9C0W1, NRK1_SCHPO ;
DR   P53915, NRK1_YEAST ;  Q9NPI5, NRK2_HUMAN ;  Q9D7C9, NRK2_MOUSE ;
//
ID   2.7.1.23
DE   NAD(+) kinase.
AN   DPN kinase.
CA   ATP + NAD(+) = ADP + NADP(+).
DR   Q56YN3, NADK1_ARATH;  Q5JK52, NADK1_ORYSJ;  Q9C5W3, NADK2_ARATH;
DR   Q53NI2, NADK2_ORYSJ;  Q60E60, NADK3_ORYSJ;  O95544, NADK_HUMAN ;
DR   P58058, NADK_MOUSE ;  Q3MBU3, PPNK1_ANAVT;  Q81TQ3, PPNK1_BACAN;
DR   Q73BU7, PPNK1_BACC1;  Q81GJ9, PPNK1_BACCR;  Q63EG5, PPNK1_BACCZ;
DR   Q9K904, PPNK1_BACHD;  Q6HLY2, PPNK1_BACHK;  Q65LA2, PPNK1_BACLD;
DR   O31612, PPNK1_BACSU;  Q5L1R5, PPNK1_GEOKA;  Q7NND8, PPNK1_GLOVI;
DR   Q92D53, PPNK1_LISIN;  Q721J8, PPNK1_LISMF;  Q8Y8D7, PPNK1_LISMO;
DR   Q8YN19, PPNK1_NOSS1;  Q8ERS9, PPNK1_OCEIH;  Q31D25, PPNK1_PROM9;
DR   Q7VE34, PPNK1_PROMA;  Q7V8H9, PPNK1_PROMM;  Q7V3C2, PPNK1_PROMP;
DR   Q46JK2, PPNK1_PROMT;  Q82P98, PPNK1_STRAW;  Q9RJS6, PPNK1_STRCO;
DR   Q5N133, PPNK1_SYNP6;  Q7U5U5, PPNK1_SYNPX;  P74430, PPNK1_SYNY3;
DR   Q8DKK1, PPNK1_THEEB;  Q3M9K5, PPNK2_ANAVT;  Q81KU5, PPNK2_BACAN;
DR   Q72Z91, PPNK2_BACC1;  Q817B5, PPNK2_BACCR;  Q633F3, PPNK2_BACCZ;
DR   Q9K808, PPNK2_BACHD;  Q6HCN5, PPNK2_BACHK;  Q65G58, PPNK2_BACLD;
DR   O34934, PPNK2_BACSU;  Q5KW59, PPNK2_GEOKA;  Q7NFK0, PPNK2_GLOVI;
DR   P65771, PPNK2_LISIN;  Q71Z81, PPNK2_LISMF;  P65770, PPNK2_LISMO;
DR   Q8Z074, PPNK2_NOSS1;  Q8EPB4, PPNK2_OCEIH;  Q319M2, PPNK2_PROM9;
DR   Q7VAW0, PPNK2_PROMA;  Q7V4D8, PPNK2_PROMM;  Q7V0I8, PPNK2_PROMP;
DR   Q46HL7, PPNK2_PROMT;  Q829B4, PPNK2_STRAW;  Q9S219, PPNK2_STRCO;
DR   Q5MZV1, PPNK2_SYNP6;  Q7U406, PPNK2_SYNPX;  P73955, PPNK2_SYNY3;
DR   Q8RR32, PPNK2_THEEB;  A1TT64, PPNK_ACIAC ;  Q6FA87, PPNK_ACIAD ;
DR   Q1ISV1, PPNK_ACIBL ;  C1F1S2, PPNK_ACIC5 ;  B9ME57, PPNK_ACIET ;
DR   B7J4J4, PPNK_ACIF2 ;  A1W4H1, PPNK_ACISJ ;  Q9YD08, PPNK_AERPE ;
DR   A4SQ27, PPNK_AERS4 ;  Q0VQV5, PPNK_ALCBS ;  B9MRX9, PPNK_ANATD ;
DR   O67055, PPNK_AQUAE ;  O30297, PPNK_ARCFU ;  Q5P1G9, PPNK_AROAE ;
DR   A1K8P2, PPNK_AZOSB ;  C1DPY6, PPNK_AZOVD ;  Q5L911, PPNK_BACFN ;
DR   Q64P72, PPNK_BACFR ;  Q5WF06, PPNK_BACSK ;  Q8A0V4, PPNK_BACTN ;
DR   Q6MII5, PPNK_BDEBA ;  B3DSX1, PPNK_BIFLD ;  Q8G5G8, PPNK_BIFLO ;
DR   B7GTM7, PPNK_BIFLS ;  Q7VRQ5, PPNK_BLOFL ;  Q492C6, PPNK_BLOPB ;
DR   Q2KW92, PPNK_BORA1 ;  Q7WGH8, PPNK_BORBR ;  O51291, PPNK_BORBU ;
DR   Q661V4, PPNK_BORGA ;  Q7W513, PPNK_BORPA ;  Q7VVX6, PPNK_BORPE ;
DR   Q8YGW9, PPNK_BRUME ;  Q8G0Z4, PPNK_BRUSU ;  B8D8Y4, PPNK_BUCA5 ;
DR   P57282, PPNK_BUCAI ;  Q8K9V8, PPNK_BUCAP ;  B8D789, PPNK_BUCAT ;
DR   Q89AR9, PPNK_BUCBP ;  B1YTJ3, PPNK_BURA4 ;  Q1BYY1, PPNK_BURCA ;
DR   B1JW12, PPNK_BURCC ;  A0K4S0, PPNK_BURCH ;  B4EDZ8, PPNK_BURCJ ;
DR   Q0BI26, PPNK_BURCM ;  A9AGC5, PPNK_BURM1 ;  Q62HC9, PPNK_BURMA ;
DR   A1V0T9, PPNK_BURMS ;  Q3JP04, PPNK_BURP1 ;  B2JGE9, PPNK_BURP8 ;
DR   B2SXB6, PPNK_BURPP ;  Q63R41, PPNK_BURPS ;  Q39JD3, PPNK_BURS3 ;
DR   Q2SZ01, PPNK_BURTA ;  A4JBR4, PPNK_BURVG ;  Q145F7, PPNK_BURXL ;
DR   A4XKP6, PPNK_CALS8 ;  A7GXF7, PPNK_CAMC5 ;  A8FL62, PPNK_CAMJ8 ;
DR   A7H4H1, PPNK_CAMJD ;  Q9PHM6, PPNK_CAMJE ;  A1VZ01, PPNK_CAMJJ ;
DR   Q5HVD0, PPNK_CAMJR ;  B9KFZ4, PPNK_CAMLR ;  Q3AAN2, PPNK_CARHZ ;
DR   P58056, PPNK_CAUCR ;  B3PJ64, PPNK_CELJU ;  A9WIJ8, PPNK_CHLAA ;
DR   B8G9X9, PPNK_CHLAD ;  Q3ANS5, PPNK_CHLCH ;  B3EI21, PPNK_CHLL2 ;
DR   B3QLE4, PPNK_CHLP8 ;  B3EPT7, PPNK_CHLPB ;  A1BJI4, PPNK_CHLPD ;
DR   B9LAP2, PPNK_CHLSY ;  B3QYG7, PPNK_CHLT3 ;  Q8KG83, PPNK_CHLTE ;
DR   Q1QXZ6, PPNK_CHRSD ;  Q7NVM0, PPNK_CHRVO ;  Q97HD7, PPNK_CLOAB ;
DR   A7FUT5, PPNK_CLOB1 ;  C3KXC0, PPNK_CLOB6 ;  A6LU50, PPNK_CLOB8 ;
DR   B2V4R1, PPNK_CLOBA ;  B2TRM3, PPNK_CLOBB ;  C1FPA6, PPNK_CLOBJ ;
DR   B1IMN2, PPNK_CLOBK ;  A7GEJ1, PPNK_CLOBL ;  B1KT47, PPNK_CLOBM ;
DR   B8I3A3, PPNK_CLOCE ;  B9E106, PPNK_CLOK1 ;  A5N7J4, PPNK_CLOK5 ;
DR   Q0TPE0, PPNK_CLOP1 ;  Q8XJE3, PPNK_CLOPE ;  A9KMB6, PPNK_CLOPH ;
DR   Q0SS07, PPNK_CLOPS ;  Q894H2, PPNK_CLOTE ;  A3DDM2, PPNK_CLOTH ;
DR   Q47XI3, PPNK_COLP3 ;  Q6NHF7, PPNK_CORDI ;  Q8FTL6, PPNK_COREF ;
DR   Q8NQM1, PPNK_CORGL ;  Q4JVX8, PPNK_CORJK ;  B6J7V3, PPNK_COXB1 ;
DR   B6IZI4, PPNK_COXB2 ;  A9KG94, PPNK_COXBN ;  A9N8H8, PPNK_COXBR ;
DR   Q83C38, PPNK_COXBU ;  Q473L9, PPNK_CUPPJ ;  Q11PL9, PPNK_CYTH3 ;
DR   Q47HJ4, PPNK_DECAR ;  Q3Z997, PPNK_DEHE1 ;  A5FS02, PPNK_DEHSB ;
DR   Q3ZZJ0, PPNK_DEHSC ;  A9BP04, PPNK_DELAS ;  B8FN99, PPNK_DESAA ;
DR   Q30Y32, PPNK_DESDG ;  A8ZWQ4, PPNK_DESOH ;  Q6AL12, PPNK_DESPS ;
DR   A4J3G3, PPNK_DESRM ;  Q72AV2, PPNK_DESVH ;  B8DKV9, PPNK_DESVM ;
DR   A1VCX9, PPNK_DESVV ;  A7ZQ55, PPNK_ECO24 ;  B7UH63, PPNK_ECO27 ;
DR   B7MIV2, PPNK_ECO45 ;  B7LDK3, PPNK_ECO55 ;  P58057, PPNK_ECO57 ;
DR   B5Z232, PPNK_ECO5E ;  B7NSB3, PPNK_ECO7I ;  B7MYQ3, PPNK_ECO81 ;
DR   B7M984, PPNK_ECO8A ;  C4ZYN2, PPNK_ECOBW ;  B1XBT5, PPNK_ECODH ;
DR   A8A3C1, PPNK_ECOHS ;  A1AEE5, PPNK_ECOK1 ;  Q0TEM5, PPNK_ECOL5 ;
DR   Q8FEY7, PPNK_ECOL6 ;  B1IVL9, PPNK_ECOLC ;  P0A7B3, PPNK_ECOLI ;
DR   B7N6K0, PPNK_ECOLU ;  B6I636, PPNK_ECOSE ;  B1LPC2, PPNK_ECOSM ;
DR   Q1R8A9, PPNK_ECOUT ;  C5BAK8, PPNK_EDWI9 ;  A4WDH9, PPNK_ENT38 ;
DR   Q830V0, PPNK_ENTFA ;  A7MHX2, PPNK_ENTS8 ;  Q6D8Y0, PPNK_ERWCT ;
DR   B2VEC5, PPNK_ERWT9 ;  C4Z0G9, PPNK_EUBE2 ;  C4ZCY4, PPNK_EUBR3 ;
DR   B0S255, PPNK_FINM2 ;  A5FJ93, PPNK_FLAJ1 ;  A6H1D1, PPNK_FLAPJ ;
DR   Q14GH2, PPNK_FRAT1 ;  A7NAY2, PPNK_FRATF ;  Q2A4H0, PPNK_FRATH ;
DR   B2SDS9, PPNK_FRATM ;  A0Q7Q7, PPNK_FRATN ;  Q0BMU7, PPNK_FRATO ;
DR   Q5NF19, PPNK_FRATT ;  A4IWQ8, PPNK_FRATW ;  Q8RGM4, PPNK_FUSNN ;
DR   C1A482, PPNK_GEMAT ;  B5EFY8, PPNK_GEOBB ;  B3E6Y9, PPNK_GEOLS ;
DR   Q39X41, PPNK_GEOMG ;  P58055, PPNK_GEOSE ;  B9M5P5, PPNK_GEOSF ;
DR   Q74BH6, PPNK_GEOSL ;  C6E6I5, PPNK_GEOSM ;  A0LXV8, PPNK_GRAFK ;
DR   Q7VKR8, PPNK_HAEDU ;  Q4QPH3, PPNK_HAEI8 ;  P44497, PPNK_HAEIN ;
DR   Q2SDI1, PPNK_HAHCH ;  A1WX34, PPNK_HALHL ;  B9LPF8, PPNK_HALLT ;
DR   Q5UXD1, PPNK_HALMA ;  B0R6L8, PPNK_HALS3 ;  Q9HNX7, PPNK_HALSA ;
DR   C4K708, PPNK_HAMD5 ;  Q17V60, PPNK_HELAH ;  Q7VGM5, PPNK_HELHP ;
DR   B0TEJ8, PPNK_HELMI ;  B6JP37, PPNK_HELP2 ;  B5Z9F8, PPNK_HELPG ;
DR   Q1CR79, PPNK_HELPH ;  Q9ZJ81, PPNK_HELPJ ;  B2UVU0, PPNK_HELPS ;
DR   O25944, PPNK_HELPY ;  Q0C0I1, PPNK_HYPNA ;  Q5QXM6, PPNK_IDILO ;
DR   B5XVJ8, PPNK_KLEP3 ;  A6TCM2, PPNK_KLEP7 ;  Q5FL98, PPNK_LACAC ;
DR   Q03QF3, PPNK_LACBA ;  Q03AS0, PPNK_LACC3 ;  Q1GB65, PPNK_LACDA ;
DR   Q04BL3, PPNK_LACDB ;  Q042A7, PPNK_LACGA ;  A8YUA3, PPNK_LACH4 ;
DR   Q74KC7, PPNK_LACJO ;  Q9CIJ4, PPNK_LACLA ;  A2RI94, PPNK_LACLM ;
DR   Q031V6, PPNK_LACLS ;  Q88V61, PPNK_LACPL ;  A5VJ17, PPNK_LACRD ;
DR   B2G6J1, PPNK_LACRJ ;  Q1WSL8, PPNK_LACS1 ;  Q38VN8, PPNK_LACSS ;
DR   C1D6U5, PPNK_LARHH ;  Q1MPL4, PPNK_LAWIP ;  Q5X168, PPNK_LEGPA ;
DR   A5IHZ7, PPNK_LEGPC ;  Q5ZRQ7, PPNK_LEGPH ;  Q5WSY8, PPNK_LEGPL ;
DR   Q6AGG7, PPNK_LEIXX ;  B1MZP8, PPNK_LEUCK ;  Q03YD3, PPNK_LEUMM ;
DR   B1HNY3, PPNK_LYSSC ;  Q2WB09, PPNK_MAGSA ;  A0L8H9, PPNK_MAGSM ;
DR   Q65UL1, PPNK_MANSM ;  A1U2D4, PPNK_MARAV ;  A6VXA6, PPNK_MARMS ;
DR   Q8TKQ5, PPNK_METAC ;  A7I809, PPNK_METB6 ;  Q46AH3, PPNK_METBF ;
DR   Q607A2, PPNK_METCA ;  Q2FQ95, PPNK_METHJ ;  Q58327, PPNK_METJA ;
DR   Q8TXD2, PPNK_METKA ;  A2SQJ8, PPNK_METLZ ;  Q8PTD1, PPNK_METMA ;
DR   A3CU51, PPNK_METMJ ;  Q6LX63, PPNK_METMP ;  B8GEC2, PPNK_METPE ;
DR   A2SL48, PPNK_METPP ;  Q2NEP6, PPNK_METST ;  O26958, PPNK_METTH ;
DR   Q2RIC1, PPNK_MOOTA ;  P0A5S7, PPNK_MYCBO ;  Q7NAU0, PPNK_MYCGA ;
DR   P47374, PPNK_MYCGE ;  B8ZRH2, PPNK_MYCLB ;  Q49897, PPNK_MYCLE ;
DR   Q740E9, PPNK_MYCPA ;  P75508, PPNK_MYCPN ;  P0A5S6, PPNK_MYCTU ;
DR   Q3IR96, PPNK_NATPD ;  B2A524, PPNK_NATTJ ;  Q5F9K3, PPNK_NEIG1 ;
DR   B4RK90, PPNK_NEIG2 ;  A9M3N9, PPNK_NEIM0 ;  P65772, PPNK_NEIMA ;
DR   P65773, PPNK_NEIMB ;  A1KT64, PPNK_NEIMF ;  Q0AHZ4, PPNK_NITEC ;
DR   Q82UK6, PPNK_NITEU ;  Q2Y6B0, PPNK_NITMU ;  Q3JBV4, PPNK_NITOC ;
DR   Q5YY98, PPNK_NOCFA ;  A7HWM6, PPNK_PARL1 ;  Q6MDK7, PPNK_PARUW ;
DR   Q9CNU2, PPNK_PASMU ;  Q03EW6, PPNK_PEDPA ;  Q3A241, PPNK_PELCD ;
DR   Q3B189, PPNK_PELLD ;  B4SGW9, PPNK_PELPB ;  A5D2Z8, PPNK_PELTS ;
DR   A9BHU3, PPNK_PETMO ;  Q7N1U6, PPNK_PHOLL ;  Q6LUA9, PPNK_PHOPR ;
DR   Q6L2M4, PPNK_PICTO ;  A1VKP7, PPNK_POLNA ;  Q12DZ0, PPNK_POLSJ ;
DR   B2RIJ4, PPNK_PORG3 ;  Q51841, PPNK_PORGI ;  B4S665, PPNK_PROA2 ;
DR   Q6A7W9, PPNK_PROAC ;  A4SGU4, PPNK_PROVI ;  Q48FT7, PPNK_PSE14 ;
DR   A6V2Y8, PPNK_PSEA7 ;  B7UUY3, PPNK_PSEA8 ;  Q02PQ1, PPNK_PSEAB ;
DR   Q9HZC0, PPNK_PSEAE ;  Q1ICQ6, PPNK_PSEE4 ;  Q4KBJ2, PPNK_PSEF5 ;
DR   C3K9T0, PPNK_PSEFS ;  Q3IKR4, PPNK_PSEHT ;  A4XWI3, PPNK_PSEMY ;
DR   A5W6U4, PPNK_PSEP1 ;  Q3KE68, PPNK_PSEPF ;  B0KFA9, PPNK_PSEPG ;
DR   Q88LC3, PPNK_PSEPK ;  B1J554, PPNK_PSEPW ;  Q87YK2, PPNK_PSESM ;
DR   Q4ZVT9, PPNK_PSEU2 ;  Q4FRP5, PPNK_PSYA2 ;  Q9V081, PPNK_PYRAB ;
DR   Q8U1V2, PPNK_PYRFU ;  O58801, PPNK_PYRHO ;  Q5JEW5, PPNK_PYRKO ;
DR   Q8XW25, PPNK_RALSO ;  Q98NA6, PPNK_RHILO ;  Q92QJ0, PPNK_RHIME ;
DR   Q7UWB8, PPNK_RHOBA ;  C1A039, PPNK_RHOE4 ;  Q21XX2, PPNK_RHOFD ;
DR   C1ASY3, PPNK_RHOOB ;  A3PML8, PPNK_RHOS1 ;  Q3IZN1, PPNK_RHOS4 ;
DR   A4WPE5, PPNK_RHOS5 ;  Q0SI70, PPNK_RHOSR ;  C3PNH0, PPNK_RICAE ;
DR   A8GNH0, PPNK_RICAH ;  A8GUT7, PPNK_RICB8 ;  A8EYX8, PPNK_RICCK ;
DR   Q92I08, PPNK_RICCN ;  Q4ULP7, PPNK_RICFE ;  Q9ZDA2, PPNK_RICPR ;
DR   C4K0J2, PPNK_RICPU ;  B0BXL4, PPNK_RICRO ;  A8GS48, PPNK_RICRS ;
DR   Q68WT8, PPNK_RICTY ;  Q21JY6, PPNK_SACD2 ;  B5F295, PPNK_SALA4 ;
DR   Q57L24, PPNK_SALCH ;  B5FS14, PPNK_SALDC ;  B5QUH0, PPNK_SALEP ;
DR   B5RD91, PPNK_SALG2 ;  B4TE58, PPNK_SALHS ;  B4T2C0, PPNK_SALNS ;
DR   Q5PFG7, PPNK_SALPA ;  B5BEA1, PPNK_SALPK ;  B4TS62, PPNK_SALSV ;
DR   P65775, PPNK_SALTI ;  P65774, PPNK_SALTY ;  A8GI41, PPNK_SERP5 ;
DR   A3D2B0, PPNK_SHEB5 ;  A6WL02, PPNK_SHEB8 ;  A9KTL1, PPNK_SHEB9 ;
DR   Q12L24, PPNK_SHEDO ;  Q07ZD2, PPNK_SHEFN ;  B0TQ38, PPNK_SHEHH ;
DR   A3QGP1, PPNK_SHELP ;  Q8EGS1, PPNK_SHEON ;  A4Y4W8, PPNK_SHEPC ;
DR   B8CS28, PPNK_SHEPW ;  A0KZB1, PPNK_SHESA ;  Q0HGL3, PPNK_SHESM ;
DR   Q0HSW4, PPNK_SHESR ;  A1RLV5, PPNK_SHESW ;  B1KQZ0, PPNK_SHEWM ;
DR   B2TYN7, PPNK_SHIB3 ;  Q31XD1, PPNK_SHIBS ;  Q32CX4, PPNK_SHIDS ;
DR   Q0T182, PPNK_SHIF8 ;  P0A7B4, PPNK_SHIFL ;  Q3YYM4, PPNK_SHISS ;
DR   Q2NS01, PPNK_SODGM ;  Q02A16, PPNK_SOLUE ;  A5V6G8, PPNK_SPHWW ;
DR   A7X0N2, PPNK_STAA1 ;  A6U0B2, PPNK_STAA2 ;  Q2FI70, PPNK_STAA3 ;
DR   Q2G1Z9, PPNK_STAA8 ;  A5IRI3, PPNK_STAA9 ;  Q2YWX6, PPNK_STAAB ;
DR   Q5HH78, PPNK_STAAC ;  A6QFL7, PPNK_STAAE ;  P65776, PPNK_STAAM ;
DR   P65777, PPNK_STAAN ;  Q6GI79, PPNK_STAAR ;  Q6GAS0, PPNK_STAAS ;
DR   A8Z0B0, PPNK_STAAT ;  P65778, PPNK_STAAW ;  B9DIP5, PPNK_STACT ;
DR   Q5HQG2, PPNK_STAEQ ;  Q8CT62, PPNK_STAES ;  Q4L515, PPNK_STAHJ ;
DR   Q49WD6, PPNK_STAS1 ;  Q3K103, PPNK_STRA1 ;  Q8E571, PPNK_STRA3 ;
DR   Q8DZK7, PPNK_STRA5 ;  A8AXJ8, PPNK_STRGC ;  Q8DU98, PPNK_STRMU ;
DR   P65781, PPNK_STRP1 ;  Q04KI9, PPNK_STRP2 ;  P0DD16, PPNK_STRP3 ;
DR   B5E4L2, PPNK_STRP4 ;  Q5XC82, PPNK_STRP6 ;  C1C794, PPNK_STRP7 ;
DR   P65783, PPNK_STRP8 ;  Q1JBT2, PPNK_STRPB ;  Q1JLR5, PPNK_STRPC ;
DR   Q1JGW5, PPNK_STRPD ;  Q1J6N4, PPNK_STRPF ;  B1IBN7, PPNK_STRPI ;
DR   B8ZPU4, PPNK_STRPJ ;  Q48TM3, PPNK_STRPM ;  P65779, PPNK_STRPN ;
DR   P0DD17, PPNK_STRPQ ;  P65780, PPNK_STRR6 ;  Q5LYV4, PPNK_STRT1 ;
DR   Q5M3G7, PPNK_STRT2 ;  C1CE84, PPNK_STRZJ ;  C1CKG4, PPNK_STRZP ;
DR   C1CRK0, PPNK_STRZT ;  Q30RL8, PPNK_SULDN ;  C3MZX9, PPNK_SULIA ;
DR   C4KJF1, PPNK_SULIK ;  C3MJB1, PPNK_SULIL ;  C3MTP3, PPNK_SULIM ;
DR   C3NJ67, PPNK_SULIN ;  C3N7W1, PPNK_SULIY ;  Q97WJ8, PPNK_SULSO ;
DR   Q96YN6, PPNK_SULTO ;  Q67NC1, PPNK_SYMTH ;  A0LG64, PPNK_SYNFM ;
DR   Q0AZE0, PPNK_SYNWW ;  C5BL09, PPNK_TERTT ;  B7IE73, PPNK_THEAB ;
DR   Q9HKH7, PPNK_THEAC ;  Q47NA3, PPNK_THEFY ;  C5A3H8, PPNK_THEGJ ;
DR   A6LN85, PPNK_THEM4 ;  Q9X255, PPNK_THEMA ;  B9K824, PPNK_THENN ;
DR   B6YUD7, PPNK_THEON ;  A5ILH3, PPNK_THEP1 ;  B0K9E7, PPNK_THEP3 ;
DR   B0K0V4, PPNK_THEPX ;  B9KXL1, PPNK_THERP ;  C6A5J6, PPNK_THESM ;
DR   B1LAU0, PPNK_THESQ ;  Q8RAC3, PPNK_THETN ;  Q979U7, PPNK_THEVO ;
DR   Q31HB0, PPNK_THICR ;  Q3SHA5, PPNK_THIDA ;  C4L8Y7, PPNK_TOLAT ;
DR   Q73MB8, PPNK_TREDE ;  O83455, PPNK_TREPA ;  B2S337, PPNK_TREPS ;
DR   Q83IC3, PPNK_TROW8 ;  Q83GX6, PPNK_TROWT ;  Q9PQW6, PPNK_UREPA ;
DR   C5CYY6, PPNK_VARPS ;  A1WGS0, PPNK_VEREI ;  A5F368, PPNK_VIBC3 ;
DR   Q9KTP8, PPNK_VIBCH ;  C3LTA3, PPNK_VIBCM ;  Q5E3A4, PPNK_VIBF1 ;
DR   A7MWW3, PPNK_VIBHB ;  Q87RX6, PPNK_VIBPA ;  B7VJW6, PPNK_VIBSL ;
DR   Q8DF58, PPNK_VIBVU ;  Q7MN93, PPNK_VIBVY ;  Q8D391, PPNK_WIGBR ;
DR   Q7MR67, PPNK_WOLSU ;  Q8PM39, PPNK_XANAC ;  Q3BV46, PPNK_XANC5 ;
DR   Q4UT86, PPNK_XANC8 ;  Q8PAD9, PPNK_XANCP ;  Q2P310, PPNK_XANOM ;
DR   Q9PBQ0, PPNK_XYLFA ;  Q87DA0, PPNK_XYLFT ;  Q8ZH09, PPNK_YERPE ;
DR   Q66DA9, PPNK_YERPS ;  Q5NMV7, PPNK_ZYMMO ;  P21373, UTR1_YEAST ;
//
ID   2.7.1.24
DE   Dephospho-CoA kinase.
AN   Dephosphocoenzyme A kinase.
CA   ATP + 3'-dephospho-CoA = ADP + CoA.
PR   PROSITE; PDOC00996;
DR   Q03941, CAB5_YEAST ;  P58897, COAE1_CORGL;  P56187, COAE2_CORGL;
DR   Q6FF48, COAE_ACIAD ;  P56186, COAE_AERHY ;  Q9JRM6, COAE_AGGAC ;
DR   Q8UJC4, COAE_AGRT5 ;  Q2ILC5, COAE_ANADE ;  Q5PB43, COAE_ANAMM ;
DR   Q3MGH8, COAE_ANAVT ;  O67792, COAE_AQUAE ;  Q5P2L4, COAE_AROAE ;
DR   Q6HSG2, COAE_BACAN ;  Q72ZF3, COAE_BACC1 ;  Q817G7, COAE_BACCR ;
DR   Q633L3, COAE_BACCZ ;  Q5LG50, COAE_BACFN ;  Q64X24, COAE_BACFR ;
DR   Q9K857, COAE_BACHD ;  Q6HCU7, COAE_BACHK ;  Q65G95, COAE_BACLD ;
DR   Q5WEG9, COAE_BACSK ;  O34932, COAE_BACSU ;  Q89YY6, COAE_BACTN ;
DR   Q6G5A8, COAE_BARHE ;  Q6G1B3, COAE_BARQU ;  Q6MIK8, COAE_BDEBA ;
DR   Q8G5L8, COAE_BIFLO ;  Q493P4, COAE_BLOPB ;  Q2KUM5, COAE_BORA1 ;
DR   Q7WF46, COAE_BORBR ;  O51497, COAE_BORBU ;  Q660X7, COAE_BORGA ;
DR   Q7W3R8, COAE_BORPA ;  Q7VSV5, COAE_BORPE ;  Q89WN9, COAE_BRAJA ;
DR   Q2YR03, COAE_BRUA2 ;  Q57AI8, COAE_BRUAB ;  P63824, COAE_BRUME ;
DR   P63825, COAE_BRUSU ;  P57299, COAE_BUCAI ;  Q8K9U1, COAE_BUCAP ;
DR   Q62GU3, COAE_BURMA ;  Q3JNF3, COAE_BURP1 ;  Q9ZF69, COAE_BURPS ;
DR   Q39JV5, COAE_BURS3 ;  Q2SZG8, COAE_BURTA ;  Q9PMD9, COAE_CAMJE ;
DR   Q5HSQ6, COAE_CAMJR ;  Q3ABL6, COAE_CARHZ ;  P58100, COAE_CAUCR ;
DR   Q5L6Y4, COAE_CHLAB ;  Q3ARZ7, COAE_CHLCH ;  Q824L6, COAE_CHLCV ;
DR   Q252Y9, COAE_CHLFF ;  Q9PJP9, COAE_CHLMU ;  Q9Z7U3, COAE_CHLPN ;
DR   Q3KLK5, COAE_CHLTA ;  Q8KD46, COAE_CHLTE ;  O84499, COAE_CHLTR ;
DR   Q7NRF7, COAE_CHRVO ;  Q97K22, COAE_CLOAB ;  Q8XIX0, COAE_CLOPE ;
DR   Q892J5, COAE_CLOTE ;  Q47VS4, COAE_COLP3 ;  P58101, COAE_CORAM ;
DR   Q6NHI5, COAE_CORDI ;  Q8FPN2, COAE_COREF ;  Q4JW20, COAE_CORJK ;
DR   Q83F01, COAE_COXBU ;  Q46X10, COAE_CUPPJ ;  Q479P3, COAE_DECAR ;
DR   Q3Z6W5, COAE_DEHE1 ;  Q3ZYN7, COAE_DEHSC ;  Q9RT73, COAE_DEIRA ;
DR   Q6AJM2, COAE_DESPS ;  Q46526, COAE_DICNO ;  P0A6J0, COAE_ECO57 ;
DR   Q8FL55, COAE_ECOL6 ;  P0A6I9, COAE_ECOLI ;  Q3YSI1, COAE_EHRCJ ;
DR   Q2GG34, COAE_EHRCR ;  Q5FHH0, COAE_EHRRG ;  Q5HBN3, COAE_EHRRW ;
DR   Q837G2, COAE_ENTFA ;  Q6D0J6, COAE_ERWCT ;  Q2JCJ1, COAE_FRASC ;
DR   Q5NEX0, COAE_FRATT ;  Q8RHR7, COAE_FUSNN ;  Q5KWC4, COAE_GEOKA ;
DR   Q39R83, COAE_GEOMG ;  Q74FU2, COAE_GEOSL ;  Q7NIP9, COAE_GLOVI ;
DR   Q5FPK0, COAE_GLUOX ;  Q7VM70, COAE_HAEDU ;  Q4QM18, COAE_HAEI8 ;
DR   P44920, COAE_HAEIN ;  Q2SBL9, COAE_HAHCH ;  Q7VFH6, COAE_HELHP ;
DR   Q9ZL12, COAE_HELPJ ;  O25502, COAE_HELPY ;  Q5R0N3, COAE_IDILO ;
DR   Q28W00, COAE_JANSC ;  Q5FIV9, COAE_LACAC ;  Q74IB6, COAE_LACJO ;
DR   Q9CHQ8, COAE_LACLA ;  Q88WV3, COAE_LACPL ;  Q38VS6, COAE_LACSS ;
DR   Q5X597, COAE_LEGPA ;  Q5ZVH3, COAE_LEGPH ;  Q5WW92, COAE_LEGPL ;
DR   Q6AF53, COAE_LEIXX ;  Q72MV4, COAE_LEPIC ;  Q8EZJ0, COAE_LEPIN ;
DR   Q92BF2, COAE_LISIN ;  Q71ZA4, COAE_LISMF ;  Q8Y6W8, COAE_LISMO ;
DR   Q2VYH5, COAE_MAGSA ;  Q65VP4, COAE_MANSM ;  Q606C5, COAE_METCA ;
DR   Q2RHF1, COAE_MOOTA ;  P63827, COAE_MYCBO ;  P47506, COAE_MYCGE ;
DR   Q50178, COAE_MYCLE ;  Q740M4, COAE_MYCPA ;  P75400, COAE_MYCPN ;
DR   P63826, COAE_MYCTU ;  Q5F691, COAE_NEIG1 ;  Q50962, COAE_NEIGO ;
DR   Q9JSS4, COAE_NEIMA ;  Q4W580, COAE_NEIMB ;  Q82WR4, COAE_NITEU ;
DR   Q2Y748, COAE_NITMU ;  Q3JEA9, COAE_NITOC ;  Q3SWG9, COAE_NITWN ;
DR   Q5YYJ6, COAE_NOCFA ;  Q8YW62, COAE_NOSS1 ;  Q2GC60, COAE_NOVAD ;
DR   Q8EPE7, COAE_OCEIH ;  Q6MEQ3, COAE_PARUW ;  Q9CPF5, COAE_PASMU ;
DR   Q3A6J1, COAE_PELCD ;  Q3B3J7, COAE_PELLD ;  Q7N158, COAE_PHOLL ;
DR   Q6LMG7, COAE_PHOPR ;  Q7MWV3, COAE_PORGI ;  Q9F7L5, COAE_PRB01 ;
DR   Q6A9M5, COAE_PROAC ;  Q31DD4, COAE_PROM9 ;  Q7VEG0, COAE_PROMA ;
DR   Q7V435, COAE_PROMM ;  Q7V3M6, COAE_PROMP ;  Q46I08, COAE_PROMT ;
DR   Q48NC2, COAE_PSE14 ;  Q9HVP8, COAE_PSEAE ;  Q4K5X1, COAE_PSEF5 ;
DR   Q3IID1, COAE_PSEHT ;  Q3K6P4, COAE_PSEPF ;  O69082, COAE_PSEPG ;
DR   Q88Q65, COAE_PSEPK ;  P36644, COAE_PSEPU ;  Q888U3, COAE_PSESM ;
DR   Q9ZEL7, COAE_PSEST ;  Q4ZYB9, COAE_PSEU2 ;  Q4FVM3, COAE_PSYA2 ;
DR   Q1QEQ3, COAE_PSYCK ;  Q8XVK2, COAE_RALSO ;  Q2KE98, COAE_RHIEC ;
DR   Q98DY2, COAE_RHILO ;  Q92TE9, COAE_RHIME ;  Q7UQ02, COAE_RHOBA ;
DR   Q21UD7, COAE_RHOFD ;  Q2J352, COAE_RHOP2 ;  Q6ND09, COAE_RHOPA ;
DR   Q21CL5, COAE_RHOPB ;  Q2RN89, COAE_RHORT ;  Q3IYG8, COAE_RHOS4 ;
DR   Q1RJM0, COAE_RICBR ;  Q92GL2, COAE_RICCN ;  Q4UN30, COAE_RICFE ;
DR   Q9ZCK0, COAE_RICPR ;  Q68W17, COAE_RICTY ;  Q21MF7, COAE_SACD2 ;
DR   Q57TB6, COAE_SALCH ;  Q5PDH9, COAE_SALPA ;  Q2RYU8, COAE_SALRD ;
DR   P63829, COAE_SALTI ;  P63828, COAE_SALTY ;  Q8EJP9, COAE_SHEON ;
DR   Q326D2, COAE_SHIBS ;  Q32JY9, COAE_SHIDS ;  Q7C397, COAE_SHIFL ;
DR   Q3Z5Q6, COAE_SHISS ;  Q5LLN2, COAE_SILPO ;  Q2NVT9, COAE_SODGM ;
DR   Q2FG49, COAE_STAA3 ;  Q2YTA2, COAE_STAAB ;  Q5HF85, COAE_STAAC ;
DR   P63830, COAE_STAAM ;  P63831, COAE_STAAN ;  Q6GG18, COAE_STAAR ;
DR   Q6G8N8, COAE_STAAS ;  P63832, COAE_STAAW ;  Q5HNL6, COAE_STAEQ ;
DR   Q8CS70, COAE_STAES ;  Q4L730, COAE_STAHJ ;  Q49YB9, COAE_STAS1 ;
DR   Q3K029, COAE_STRA1 ;  Q8E449, COAE_STRA3 ;  Q8DYJ2, COAE_STRA5 ;
DR   Q82A24, COAE_STRAW ;  Q9S2K7, COAE_STRCO ;  Q8DSZ0, COAE_STRMU ;
DR   P58102, COAE_STRP1 ;  P0DA44, COAE_STRP3 ;  Q5XDE3, COAE_STRP6 ;
DR   P63834, COAE_STRP8 ;  Q48UU5, COAE_STRPM ;  Q97R60, COAE_STRPN ;
DR   P0DA45, COAE_STRPQ ;  Q8DQ32, COAE_STRR6 ;  Q5M0N9, COAE_STRT1 ;
DR   Q5M575, COAE_STRT2 ;  Q30NW0, COAE_SULDN ;  Q67R57, COAE_SYMTH ;
DR   Q2LUP6, COAE_SYNAS ;  Q31RL4, COAE_SYNE7 ;  Q2JWS5, COAE_SYNJA ;
DR   Q2JLX1, COAE_SYNJB ;  Q5N2P0, COAE_SYNP6 ;  Q7U3S5, COAE_SYNPX ;
DR   Q3AVV9, COAE_SYNS9 ;  Q3AGR0, COAE_SYNSC ;  Q55515, COAE_SYNY3 ;
DR   Q8DKG1, COAE_THEEB ;  Q47QN9, COAE_THEFY ;  Q9X1A7, COAE_THEMA ;
DR   Q72K90, COAE_THET2 ;  Q56416, COAE_THET8 ;  Q8RBE5, COAE_THETN ;
DR   Q31I33, COAE_THICR ;  Q3SGD0, COAE_THIDA ;  Q73M71, COAE_TREDE ;
DR   O83319, COAE_TREPA ;  Q9KPE3, COAE_VIBCH ;  Q5E2R2, COAE_VIBF1 ;
DR   Q87LT4, COAE_VIBPA ;  Q56741, COAE_VIBVU ;  Q7MHT5, COAE_VIBVY ;
DR   Q8D308, COAE_WIGBR ;  Q73IH9, COAE_WOLPM ;  Q7M7Q5, COAE_WOLSU ;
DR   Q5GT26, COAE_WOLTR ;  Q8PHK7, COAE_XANAC ;  Q3BQ76, COAE_XANC5 ;
DR   Q4UXU8, COAE_XANC8 ;  Q56764, COAE_XANCP ;  Q2P5F7, COAE_XANOM ;
DR   Q5H2I4, COAE_XANOR ;  Q9PAI2, COAE_XYLFA ;  Q87AA7, COAE_XYLFT ;
DR   Q8ZBI0, COAE_YERPE ;  Q66EJ1, COAE_YERPS ;  Q5NRJ0, COAE_ZYMMO ;
DR   Q13057, COASY_HUMAN;  Q9DBL7, COASY_MOUSE;  Q8MIR4, COASY_PIG  ;
//
ID   2.7.1.25
DE   Adenylyl-sulfate kinase.
AN   Adenosine 5'-phosphosulfate kinase.
AN   Adenylylsulfate kinase.
AN   APS kinase.
CA   ATP + adenylyl sulfate = ADP + 3'-phosphoadenylyl sulfate.
CC   -!- The human phosphoadenosine-phosphosulfate synthase (PAPS) system is a
CC       bifunctional enzyme: ATP sulfurylase, which catalyzes the formation
CC       of adenosine 5'-phosphosulfate (APS) from ATP and inorganic sulfate
CC       and the second step is catalyzed by the APS kinase portion of
CC       3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthase, which involves
CC       the formation of PAPS from enzyme bound APS and ATP.
CC   -!- This is in contrast to what is found in bacteria, yeasts, fungi and
CC       plants, where the formation of PAPS is carried out by two individual
CC       polypeptides, EC 2.7.7.4 and EC 2.7.1.25.
DR   Q9KCT0, CYSC1_BACHD;  O34577, CYSC1_BACSU;  Q9K7H6, CYSC2_BACHD;
DR   O06735, CYSC2_BACSU;  P29811, CYSC2_PSEAE;  B0CAX3, CYSC_ACAM1 ;
DR   A0KP33, CYSC_AERHH ;  Q9YCR6, CYSC_AERPE ;  A4SRG6, CYSC_AERS4 ;
DR   O29953, CYSC_ARCFU ;  A7Z4I0, CYSC_BACA2 ;  Q5LES5, CYSC_BACFN ;
DR   Q64VR1, CYSC_BACFR ;  Q65JT8, CYSC_BACLD ;  A8FD25, CYSC_BACP2 ;
DR   Q8AAQ1, CYSC_BACTN ;  A6KXG9, CYSC_BACV8 ;  P57497, CYSC_BUCAI ;
DR   Q8K9D4, CYSC_BUCAP ;  Q0BI00, CYSC_BURCM ;  B2T3K5, CYSC_BURPP ;
DR   Q13ZJ7, CYSC_BURXL ;  B9LKC1, CYSC_CHLSY ;  A8ANW4, CYSC_CITK8 ;
DR   Q97MT8, CYSC_CLOAB ;  A5N960, CYSC_CLOK5 ;  B7K8N5, CYSC_CYAP7 ;
DR   B7K5B1, CYSC_CYAP8 ;  C1CVW7, CYSC_DEIDV ;  Q1IYI1, CYSC_DEIGD ;
DR   P56861, CYSC_DEIRA ;  A7ZQJ4, CYSC_ECO24 ;  B7UHG9, CYSC_ECO27 ;
DR   B7MKM4, CYSC_ECO45 ;  B7LEG8, CYSC_ECO55 ;  P0A6J2, CYSC_ECO57 ;
DR   B5Z3B2, CYSC_ECO5E ;  B7NT94, CYSC_ECO7I ;  B7MYQ5, CYSC_ECO81 ;
DR   B7LXG2, CYSC_ECO8A ;  C4ZZQ4, CYSC_ECOBW ;  B1XCS6, CYSC_ECODH ;
DR   A8A3M9, CYSC_ECOHS ;  A1AEU4, CYSC_ECOK1 ;  Q0TEA8, CYSC_ECOL5 ;
DR   Q8FEJ2, CYSC_ECOL6 ;  B1IUS9, CYSC_ECOLC ;  P0A6J1, CYSC_ECOLI ;
DR   B7N6Y0, CYSC_ECOLU ;  B6I6E0, CYSC_ECOSE ;  B1LQ71, CYSC_ECOSM ;
DR   Q1R7U1, CYSC_ECOUT ;  A4WDV5, CYSC_ENT38 ;  A7MJ70, CYSC_ENTS8 ;
DR   B2VG00, CYSC_ERWT9 ;  B7LWK5, CYSC_ESCF3 ;  B9M543, CYSC_GEOSF ;
DR   A5G863, CYSC_GEOUR ;  B8D0S4, CYSC_HALOH ;  B5XV31, CYSC_KLEP3 ;
DR   A6TD42, CYSC_KLEP7 ;  Q88X60, CYSC_LACPL ;  A1U3X8, CYSC_MARAV ;
DR   B0JL16, CYSC_MICAN ;  Q1D6P1, CYSC_MYXXD ;  Q8EQN3, CYSC_OCEIH ;
DR   Q7VE24, CYSC_PROMA ;  P57702, CYSC_PSEAE ;  Q1I2K4, CYSC_PSEE4 ;
DR   P56858, CYSC_PYRAB ;  Q7UQW3, CYSC_RHOBA ;  B5F414, CYSC_SALA4 ;
DR   A9MF25, CYSC_SALAR ;  Q57KJ1, CYSC_SALCH ;  B5FTS8, CYSC_SALDC ;
DR   B5QW21, CYSC_SALEP ;  B5RDQ6, CYSC_SALG2 ;  B4TFX0, CYSC_SALHS ;
DR   B4T460, CYSC_SALNS ;  Q5PEH3, CYSC_SALPA ;  A9N2D7, CYSC_SALPB ;
DR   C0PXB0, CYSC_SALPC ;  B5BEY7, CYSC_SALPK ;  B4TTW4, CYSC_SALSV ;
DR   P63890, CYSC_SALTI ;  P63889, CYSC_SALTY ;  A1S9N4, CYSC_SHEAM ;
DR   B8EE63, CYSC_SHEB2 ;  A3D819, CYSC_SHEB5 ;  A6WJU6, CYSC_SHEB8 ;
DR   A9L392, CYSC_SHEB9 ;  Q12QM6, CYSC_SHEDO ;  Q07Y94, CYSC_SHEFN ;
DR   B0TTD2, CYSC_SHEHH ;  Q8EB13, CYSC_SHEON ;  A8H0A6, CYSC_SHEPA ;
DR   A4Y9X0, CYSC_SHEPC ;  A0KTI5, CYSC_SHESA ;  Q0HFM7, CYSC_SHESM ;
DR   Q0HYA3, CYSC_SHESR ;  A1RGG0, CYSC_SHESW ;  B2TZI1, CYSC_SHIB3 ;
DR   Q31XB2, CYSC_SHIBS ;  Q32CI0, CYSC_SHIDS ;  Q0T1I1, CYSC_SHIF8 ;
DR   Q83JX9, CYSC_SHIFL ;  Q3YYB2, CYSC_SHISS ;  B9DLK2, CYSC_STACT ;
DR   Q5HL02, CYSC_STAEQ ;  Q8CR04, CYSC_STAES ;  Q4L9E6, CYSC_STAHJ ;
DR   Q49UM5, CYSC_STAS1 ;  Q2JUC0, CYSC_SYNJA ;  Q2JLM3, CYSC_SYNJB ;
DR   B1XN05, CYSC_SYNP2 ;  P72940, CYSC_SYNY3 ;  Q8DJ87, CYSC_THEEB ;
DR   B5YJA6, CYSC_THEYD ;  Q9KP21, CYSC_VIBCH ;  Q87SX6, CYSC_VIBPA ;
DR   Q8DE75, CYSC_VIBVU ;  Q7MPF0, CYSC_VIBVY ;  Q8ZBP3, CYSC_YERPE ;
DR   Q10600, CYSNC_MYCTU;  O50274, CYSNC_PSEAE;  Q7UMW2, CYSNC_RHOBA;
DR   Q9PD78, CYSNC_XYLFA;  Q87DG7, CYSNC_XYLFT;  Q43295, KAP1_ARATH ;
DR   O49196, KAP2_ARATH ;  O49204, KAPS_CATRO ;  Q92203, KAPS_EMENI ;
DR   Q12657, KAPS_PENCH ;  Q9HGF8, KAPS_SACBA ;  Q9C2Y6, KAPS_SACPS ;
DR   Q9P7G9, KAPS_SCHPO ;  Q02196, KAPS_YEAST ;  P28604, NODQ_AZOBR ;
DR   P13442, NODQ_RHIME ;  P72339, NODQ_RHIS3 ;  O07309, NODQ_RHISB ;
DR   P52978, NODQ_RHITR ;  O54820, PAPS1_CAVPO;  O43252, PAPS1_HUMAN;
DR   Q60967, PAPS1_MOUSE;  O95340, PAPS2_HUMAN;  O88428, PAPS2_MOUSE;
DR   Q27128, PAPSS_URECA;  A9ENT2, SATC1_SORC5;  A9G7W0, SATC2_SORC5;
DR   O67174, SATC_AQUAE ;
//
ID   2.7.1.26
DE   Riboflavin kinase.
AN   Flavokinase.
AN   RFK.
CA   ATP + riboflavin = ADP + FMN.
CF   Magnesium or zinc or manganese.
CC   -!- The cofactors FMN and FAD participate in numerous processes in all
CC       organisms, including mitochondrial electron transport,
CC       photosynthesis, fatty-acid oxidation, and metabolism of vitamin B(6),
CC       vitamin B12 and folates.
CC   -!- While monofunctional riboflavin kinase is found in eukaryotes, some
CC       bacteria have a bifunctional enzyme that exhibits both this activity
CC       and that of EC 2.7.7.2.
CC   -!- In Bacillus subtilis, ATP can be replaced by other phosphate donors
CC       but with decreasing enzyme activity in the order ATP > dATP > CTP >
CC       UTP.
DR   Q7NBZ0, MNMA_MYCGA ;  P54575, RIBC_BACSU ;  P57250, RIBF_BUCAI ;
DR   Q8K9Z1, RIBF_BUCAP ;  Q59263, RIBF_CORAM ;  P0AG42, RIBF_ECO57 ;
DR   P0AG41, RIBF_ECOL6 ;  P0AG40, RIBF_ECOLI ;  P44957, RIBF_HAEIN ;
DR   P47391, RIBF_MYCGE ;  P75587, RIBF_MYCPN ;  P22990, RIBF_PSEFL ;
DR   O84990, RIBF_RHOOP ;  P0AG43, RIBF_SHIFL ;  P73651, RIBF_SYNY3 ;
DR   Q75DY2, RIFK_ASHGO ;  A1C603, RIFK_ASPCL ;  Q4WHD2, RIFK_ASPFU ;
DR   A2QFH1, RIFK_ASPNC ;  Q2UMM4, RIFK_ASPOR ;  Q0CHR1, RIFK_ASPTN ;
DR   Q6FM49, RIFK_CANGA ;  P0C5D9, RIFK_CHAGB ;  O76206, RIFK_DROME ;
DR   Q5AW61, RIFK_EMENI ;  Q969G6, RIFK_HUMAN ;  Q6CT57, RIFK_KLULA ;
DR   A5E1A0, RIFK_LODEL ;  A4QQ05, RIFK_MAGO7 ;  Q8CFV9, RIFK_MOUSE ;
DR   A1DG00, RIFK_NEOFI ;  Q6M923, RIFK_NEUCR ;  A5DAH9, RIFK_PICGU ;
DR   A3M0C9, RIFK_PICST ;  O74866, RIFK_SCHPO ;  Q6CG11, RIFK_YARLI ;
DR   Q03778, RIFK_YEAST ;
//
ID   2.7.1.27
DE   Erythritol kinase.
CA   ATP + erythritol = ADP + D-erythritol 4-phosphate.
//
ID   2.7.1.28
DE   Triokinase.
AN   Triose kinase.
CA   ATP + D-glyceraldehyde = ADP + D-glyceraldehyde 3-phosphate.
//
ID   2.7.1.29
DE   Glycerone kinase.
AN   Dihydroxyacetone kinase.
CA   ATP + glycerone = ADP + glycerone phosphate.
DR   O13902, DAK1_SCHPO ;  P54838, DAK1_YEAST ;  O74215, DAK2_SCHPO ;
DR   P43550, DAK2_YEAST ;  O60017, DAK_PICAN  ;  O74192, DAK_PICPA  ;
DR   Q58DK4, DHAK_BOVIN ;  P45510, DHAK_CITFR ;  Q55EE0, DHAK_DICDI ;
DR   Q3LXA3, DHAK_HUMAN ;  Q8VC30, DHAK_MOUSE ;  Q4KLZ6, DHAK_RAT   ;
//
ID   2.7.1.30
DE   Glycerol kinase.
AN   ATP:glycerol 3-phosphotransferase.
AN   Glycerokinase.
CA   ATP + glycerol = ADP + sn-glycerol 3-phosphate.
CC   -!- Glycerone and L-glyceraldehyde can act as acceptors.
CC   -!- UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and
CC       GTP) can act as donors.
PR   PROSITE; PDOC00408;
DR   Q893Q3, GLPK1_CLOTE;  Q88ZF1, GLPK1_LACPL;  Q51390, GLPK1_PSEAE;
DR   Q828K5, GLPK1_STRAW;  Q9ADA7, GLPK1_STRCO;  Q4J9R1, GLPK1_SULAC;
DR   Q97XW1, GLPK1_SULSO;  Q9X049, GLPK1_THEMA;  Q891B8, GLPK2_CLOTE;
DR   Q14410, GLPK2_HUMAN;  Q88YD9, GLPK2_LACPL;  Q4R4D5, GLPK2_MACFA;
DR   Q9WU65, GLPK2_MOUSE;  Q9HY41, GLPK2_PSEAE;  Q827G1, GLPK2_STRAW;
DR   Q9RJM2, GLPK2_STRCO;  Q4J7A3, GLPK2_SULAC;  P95907, GLPK2_SULSO;
DR   Q9X1E4, GLPK2_THEMA;  Q14409, GLPK3_HUMAN;  Q826J2, GLPK3_STRAW;
DR   Q08D86, GLPK5_BOVIN;  Q5ZMJ4, GLPK5_CHICK;  A0JPE9, GLPK5_DANRE;
DR   Q6ZS86, GLPK5_HUMAN;  Q8BX05, GLPK5_MOUSE;  Q6GP95, GLPK5_XENLA;
DR   B0CB70, GLPK_ACAM1 ;  A1TJR8, GLPK_ACIAC ;  Q6FDN3, GLPK_ACIAD ;
DR   Q1IMB2, GLPK_ACIBL ;  A5G146, GLPK_ACICJ ;  B9MBT7, GLPK_ACIET ;
DR   A1W309, GLPK_ACISJ ;  A0KIT3, GLPK_AERHH ;  A4SPA7, GLPK_AERS4 ;
DR   B9J7X6, GLPK_AGRRK ;  Q8U940, GLPK_AGRT5 ;  B9JZR4, GLPK_AGRVS ;
DR   Q0VRN6, GLPK_ALCBS ;  Q0A923, GLPK_ALHEH ;  B6ER09, GLPK_ALISL ;
DR   A6TKR6, GLPK_ALKMQ ;  A8MG11, GLPK_ALKOO ;  B4S2H6, GLPK_ALTMD ;
DR   Q3M3M2, GLPK_ANAVT ;  O66746, GLPK_AQUAE ;  Q5P212, GLPK_AROAE ;
DR   A1R6X6, GLPK_ARTAT ;  B8H8T1, GLPK_ARTCA ;  A8I8V7, GLPK_AZOC5 ;
DR   A1K962, GLPK_AZOSB ;  C1DHV0, GLPK_AZOVD ;  A7Z2U3, GLPK_BACA2 ;
DR   C3P2T3, GLPK_BACAA ;  C3LCY4, GLPK_BACAC ;  A0RAP3, GLPK_BACAH ;
DR   Q81U58, GLPK_BACAN ;  B7JCV9, GLPK_BACC0 ;  Q73CE0, GLPK_BACC1 ;
DR   B7IKB1, GLPK_BACC2 ;  C1EKE4, GLPK_BACC3 ;  B7HG04, GLPK_BACC4 ;
DR   B7HYU3, GLPK_BACC7 ;  A7GLY7, GLPK_BACCN ;  B9IT52, GLPK_BACCQ ;
DR   Q81GZ2, GLPK_BACCR ;  Q63EX2, GLPK_BACCZ ;  Q9KDW8, GLPK_BACHD ;
DR   Q6HMD5, GLPK_BACHK ;  Q65M11, GLPK_BACLD ;  P18157, GLPK_BACSU ;
DR   A9VI58, GLPK_BACWK ;  Q6MJQ2, GLPK_BDEBA ;  B2IE09, GLPK_BEII9 ;
DR   C5C1C4, GLPK_BEUC1 ;  Q0SNS0, GLPK_BORAP ;  Q7WF38, GLPK_BORBR ;
DR   O51257, GLPK_BORBU ;  B7J1G9, GLPK_BORBZ ;  B5RL65, GLPK_BORDL ;
DR   Q662C3, GLPK_BORGA ;  B2RZV0, GLPK_BORHD ;  Q7W3R1, GLPK_BORPA ;
DR   Q7VSU7, GLPK_BORPE ;  Q0IID9, GLPK_BOVIN ;  C0QVC0, GLPK_BRAHW ;
DR   Q89UK6, GLPK_BRAJA ;  A5ES06, GLPK_BRASB ;  A4YLX6, GLPK_BRASO ;
DR   C0Z5A8, GLPK_BREBN ;  A9MB89, GLPK_BRUC2 ;  Q8YBR2, GLPK_BRUME ;
DR   A5VUC1, GLPK_BRUO2 ;  A9WYC6, GLPK_BRUSI ;  Q8FWK8, GLPK_BRUSU ;
DR   B1YWB2, GLPK_BURA4 ;  Q1BTT7, GLPK_BURCA ;  B1JY43, GLPK_BURCC ;
DR   A0KAA1, GLPK_BURCH ;  Q0BC36, GLPK_BURCM ;  A9AFH2, GLPK_BURM1 ;
DR   B2JD95, GLPK_BURP8 ;  B2SYH7, GLPK_BURPP ;  Q63X50, GLPK_BURPS ;
DR   Q2T0Z3, GLPK_BURTA ;  A4JHM8, GLPK_BURVG ;  Q13UE3, GLPK_BURXL ;
DR   Q21944, GLPK_CAEEL ;  Q3AB25, GLPK_CARHZ ;  A9WJ21, GLPK_CHLAA ;
DR   B8GC51, GLPK_CHLAD ;  B9LD34, GLPK_CHLSY ;  Q1QVQ3, GLPK_CHRSD ;
DR   Q7P1G2, GLPK_CHRVO ;  A8AL00, GLPK_CITK8 ;  A5CS23, GLPK_CLAM3 ;
DR   Q97JG4, GLPK_CLOAB ;  A7FX30, GLPK_CLOB1 ;  C3L254, GLPK_CLOB6 ;
DR   A6M1Y8, GLPK_CLOB8 ;  B2V358, GLPK_CLOBA ;  B2TN12, GLPK_CLOBB ;
DR   A5I5M0, GLPK_CLOBH ;  C1FUW6, GLPK_CLOBJ ;  B1IKJ7, GLPK_CLOBK ;
DR   A7GH02, GLPK_CLOBL ;  B1KYK0, GLPK_CLOBM ;  Q0TMA0, GLPK_CLOP1 ;
DR   Q8XHD3, GLPK_CLOPE ;  A9KQC2, GLPK_CLOPH ;  Q0SQ01, GLPK_CLOPS ;
DR   Q8FLY8, GLPK_COREF ;  A4QHT1, GLPK_CORGB ;  Q8NLP9, GLPK_CORGL ;
DR   C4LGQ3, GLPK_CORK4 ;  A9KCL1, GLPK_COXBN ;  A9NCY5, GLPK_COXBR ;
DR   Q83D14, GLPK_COXBU ;  B7K2C0, GLPK_CYAP8 ;  Q47ER3, GLPK_DECAR ;
DR   Q9RT38, GLPK_DEIRA ;  A9BRV2, GLPK_DELAS ;  C6C1M7, GLPK_DESAD ;
DR   B8J0H2, GLPK_DESDA ;  Q316D5, GLPK_DESDG ;  B8FXS7, GLPK_DESHD ;
DR   C4XGV9, GLPK_DESMR ;  A4J8E6, GLPK_DESRM ;  Q726H4, GLPK_DESVH ;
DR   B8DL62, GLPK_DESVM ;  A1VA10, GLPK_DESVV ;  Q54VT8, GLPK_DICDI ;
DR   A5EWH1, GLPK_DICNV ;  A7ZUE0, GLPK_ECO24 ;  B7UNP6, GLPK_ECO27 ;
DR   B7MI58, GLPK_ECO45 ;  B7LA23, GLPK_ECO55 ;  P0A6F4, GLPK_ECO57 ;
DR   B5YZ64, GLPK_ECO5E ;  B7NU81, GLPK_ECO7I ;  B7N2R7, GLPK_ECO81 ;
DR   B7M6X7, GLPK_ECO8A ;  C5A093, GLPK_ECOBW ;  B1XB92, GLPK_ECODH ;
DR   A8A731, GLPK_ECOHS ;  Q0TAD8, GLPK_ECOL5 ;  Q8FBC3, GLPK_ECOL6 ;
DR   B1IVF3, GLPK_ECOLC ;  P0A6F3, GLPK_ECOLI ;  B7NFM3, GLPK_ECOLU ;
DR   B1LNM9, GLPK_ECOSM ;  A4WG72, GLPK_ENT38 ;  O34153, GLPK_ENTCA ;
DR   O34154, GLPK_ENTFA ;  B7LUS9, GLPK_ESCF3 ;  C4ZGB4, GLPK_EUBR3 ;
DR   B0TWZ7, GLPK_FRAP2 ;  Q14JU8, GLPK_FRAT1 ;  A7NE12, GLPK_FRATF ;
DR   Q2A1W9, GLPK_FRATH ;  B2SF32, GLPK_FRATM ;  A0Q880, GLPK_FRATN ;
DR   Q0BKK9, GLPK_FRATO ;  Q5NIE5, GLPK_FRATT ;  A4IW85, GLPK_FRATW ;
DR   Q8RHZ9, GLPK_FUSNN ;  B5EB79, GLPK_GEOBB ;  Q5L091, GLPK_GEOKA ;
DR   B3E6Z6, GLPK_GEOLS ;  Q39V17, GLPK_GEOMG ;  Q749I1, GLPK_GEOSL ;
DR   C6E1L8, GLPK_GEOSM ;  C5DA06, GLPK_GEOSW ;  Q7NJT1, GLPK_GLOVI ;
DR   Q5FP70, GLPK_GLUOX ;  Q4QMM7, GLPK_HAEI8 ;  A5UE44, GLPK_HAEIE ;
DR   A5UHH7, GLPK_HAEIG ;  P44400, GLPK_HAEIN ;  A1WT61, GLPK_HALHL ;
DR   Q5V4I4, GLPK_HALMA ;  B8CW97, GLPK_HALOH ;  B0R6S2, GLPK_HALS3 ;
DR   Q9HNS5, GLPK_HALSA ;  Q18JE8, GLPK_HALWD ;  A4G1Q7, GLPK_HERAR ;
DR   P32189, GLPK_HUMAN ;  A6SUL1, GLPK_JANMA ;  B5XTD4, GLPK_KLEP3 ;
DR   A6TFR2, GLPK_KLEP7 ;  Q5FHZ6, GLPK_LACAC ;  Q047N5, GLPK_LACDB ;
DR   Q9CG64, GLPK_LACLA ;  A5VKE8, GLPK_LACRD ;  B2G7U6, GLPK_LACRJ ;
DR   Q1WVJ0, GLPK_LACS1 ;  Q38XX6, GLPK_LACSS ;  Q6AGR0, GLPK_LEIXX ;
DR   B0SG67, GLPK_LEPBA ;  B0SPA9, GLPK_LEPBP ;  B1Y1L9, GLPK_LEPCP ;
DR   Q92BH6, GLPK_LISIN ;  C1KVI5, GLPK_LISMC ;  Q71ZD2, GLPK_LISMF ;
DR   B8DHL0, GLPK_LISMH ;  Q8Y6Z2, GLPK_LISMO ;  A0AIY7, GLPK_LISW6 ;
DR   B9EBI8, GLPK_MACCJ ;  A1U326, GLPK_MARAV ;  A6W2C1, GLPK_MARMS ;
DR   Q11HY2, GLPK_MESSB ;  B7KN92, GLPK_METC4 ;  A9W8T7, GLPK_METEP ;
DR   B8IKN3, GLPK_METNO ;  B1ZGW7, GLPK_METPB ;  A2SM29, GLPK_METPP ;
DR   B1LWN6, GLPK_METRJ ;  Q64516, GLPK_MOUSE ;  B1MFT1, GLPK_MYCA9 ;
DR   Q2SSQ8, GLPK_MYCCT ;  Q7NC65, GLPK_MYCGA ;  P47284, GLPK_MYCGE ;
DR   A4T5Y1, GLPK_MYCGI ;  Q9CB81, GLPK_MYCLE ;  Q6MTY7, GLPK_MYCMS ;
DR   Q8EVD0, GLPK_MYCPE ;  P75064, GLPK_MYCPN ;  Q98QY9, GLPK_MYCPU ;
DR   A5U920, GLPK_MYCTA ;  O69664, GLPK_MYCTU ;  A1TGD7, GLPK_MYCVP ;
DR   Q1CXI5, GLPK_MYXXD ;  B2A2C4, GLPK_NATTJ ;  Q0AEC9, GLPK_NITEC ;
DR   Q1QR91, GLPK_NITHX ;  Q5Z175, GLPK_NOCFA ;  Q8YW05, GLPK_NOSS1 ;
DR   Q8ENK7, GLPK_OCEIH ;  A6WXV2, GLPK_OCHA4 ;  B6JJF0, GLPK_OLICO ;
DR   A6LCZ1, GLPK_PARD8 ;  P57944, GLPK_PASMU ;  Q03DS8, GLPK_PEDPA ;
DR   A9BJ81, GLPK_PETMO ;  Q7MYB6, GLPK_PHOLL ;  A1VJ23, GLPK_POLNA ;
DR   Q12GA2, GLPK_POLSJ ;  Q48F01, GLPK_PSE14 ;  Q15Q03, GLPK_PSEA6 ;
DR   Q1IE16, GLPK_PSEE4 ;  Q4K734, GLPK_PSEF5 ;  C3KBM0, GLPK_PSEFS ;
DR   A4XXN1, GLPK_PSEMY ;  A5VZG7, GLPK_PSEP1 ;  Q3K7I5, GLPK_PSEPF ;
DR   B0KUG0, GLPK_PSEPG ;  Q88NX8, GLPK_PSEPK ;  Q87XL0, GLPK_PSESM ;
DR   O87924, GLPK_PSETO ;  Q4ZPI7, GLPK_PSEU2 ;  A1SZE1, GLPK_PSYIN ;
DR   Q9V207, GLPK_PYRAB ;  Q8TZI8, GLPK_PYRFU ;  O93623, GLPK_PYRKO ;
DR   B2UF87, GLPK_RALPJ ;  Q8XUY1, GLPK_RALSO ;  Q63060, GLPK_RAT   ;
DR   A9WS93, GLPK_RENSM ;  Q98M73, GLPK_RHILO ;  O86033, GLPK_RHIME ;
DR   C3MG71, GLPK_RHISN ;  Q7UTP4, GLPK_RHOBA ;  B6IQI0, GLPK_RHOCS ;
DR   Q21S75, GLPK_RHOFD ;  Q2IZ89, GLPK_RHOP2 ;  Q07K31, GLPK_RHOP5 ;
DR   Q6N3I8, GLPK_RHOPA ;  Q133H2, GLPK_RHOPS ;  B3QH88, GLPK_RHOPT ;
DR   Q2RST6, GLPK_RHORT ;  A3PJB4, GLPK_RHOS1 ;  Q3J317, GLPK_RHOS4 ;
DR   A4WRT7, GLPK_RHOS5 ;  B9KRP4, GLPK_RHOSK ;  Q165D5, GLPK_ROSDO ;
DR   A5UU55, GLPK_ROSS1 ;  A4FNR2, GLPK_SACEN ;  B5F0R7, GLPK_SALA4 ;
DR   A9MI40, GLPK_SALAR ;  Q57HD1, GLPK_SALCH ;  B5FPT4, GLPK_SALDC ;
DR   B5QXL5, GLPK_SALEP ;  B5RF85, GLPK_SALG2 ;  B4TCM2, GLPK_SALHS ;
DR   B4T0T2, GLPK_SALNS ;  Q5PIS3, GLPK_SALPA ;  A9MZH4, GLPK_SALPB ;
DR   C0Q436, GLPK_SALPC ;  B5BJK3, GLPK_SALPK ;  B4TPU7, GLPK_SALSV ;
DR   Q8Z2Y6, GLPK_SALTI ;  Q8ZKP3, GLPK_SALTY ;  A1S2E6, GLPK_SHEAM ;
DR   B8E4K9, GLPK_SHEB2 ;  A3CZL0, GLPK_SHEB5 ;  A6WIC0, GLPK_SHEB8 ;
DR   A9KY18, GLPK_SHEB9 ;  Q07WH4, GLPK_SHEFN ;  B0TQM6, GLPK_SHEHH ;
DR   A3QIN4, GLPK_SHELP ;  Q8E9N7, GLPK_SHEON ;  A8H995, GLPK_SHEPA ;
DR   A4Y2M5, GLPK_SHEPC ;  B8CM45, GLPK_SHEPW ;  A0L1Q5, GLPK_SHESA ;
DR   A8FQ89, GLPK_SHESH ;  Q0HE70, GLPK_SHESM ;  Q0HZS9, GLPK_SHESR ;
DR   A1REY5, GLPK_SHESW ;  B1KKY8, GLPK_SHEWM ;  B2TWC2, GLPK_SHIB3 ;
DR   Q31U64, GLPK_SHIBS ;  Q32A92, GLPK_SHIDS ;  Q7UB84, GLPK_SHIFL ;
DR   Q5LWR1, GLPK_SILPO ;  Q01V13, GLPK_SOLUE ;  A5VE44, GLPK_SPHWW ;
DR   A7X1U3, GLPK_STAA1 ;  A6U1B8, GLPK_STAA2 ;  Q2FHD9, GLPK_STAA3 ;
DR   Q2FYZ5, GLPK_STAA8 ;  A5ISI2, GLPK_STAA9 ;  Q2YXR6, GLPK_STAAB ;
DR   Q5HGD2, GLPK_STAAC ;  A6QGJ8, GLPK_STAAE ;  P63741, GLPK_STAAM ;
DR   P99113, GLPK_STAAN ;  Q6GHD5, GLPK_STAAR ;  Q6G9R3, GLPK_STAAS ;
DR   A8Z1X0, GLPK_STAAT ;  Q8NWX7, GLPK_STAAW ;  Q5HPP1, GLPK_STAEQ ;
DR   Q8CSS0, GLPK_STAES ;  Q4L607, GLPK_STAHJ ;  Q49X93, GLPK_STAS1 ;
DR   Q3K3A6, GLPK_STRA1 ;  Q8E794, GLPK_STRA3 ;  Q8E1T0, GLPK_STRA5 ;
DR   A8AVX5, GLPK_STRGC ;  P25013, GLPK_STRGR ;  B4SJT3, GLPK_STRM5 ;
DR   B2FI02, GLPK_STRMK ;  Q99YI7, GLPK_STRP1 ;  Q04HZ0, GLPK_STRP2 ;
DR   P0DA16, GLPK_STRP3 ;  B5E3S7, GLPK_STRP4 ;  Q5XAJ9, GLPK_STRP6 ;
DR   C1CBG2, GLPK_STRP7 ;  Q8NZW9, GLPK_STRP8 ;  Q1JAF2, GLPK_STRPB ;
DR   Q1JKK3, GLPK_STRPC ;  Q1JFJ5, GLPK_STRPD ;  Q1J5E4, GLPK_STRPF ;
DR   A2RD27, GLPK_STRPG ;  B1I9Z6, GLPK_STRPI ;  B8ZQ22, GLPK_STRPJ ;
DR   Q48RX6, GLPK_STRPM ;  P63742, GLPK_STRPN ;  P0DA17, GLPK_STRPQ ;
DR   B2INK5, GLPK_STRPS ;  B5XMM6, GLPK_STRPZ ;  P63743, GLPK_STRR6 ;
DR   A3CPV3, GLPK_STRSV ;  B9DV90, GLPK_STRU0 ;  C1CHI6, GLPK_STRZJ ;
DR   C1CNF8, GLPK_STRZP ;  C1CUA3, GLPK_STRZT ;  C3N2M3, GLPK_SULIA ;
DR   C4KEH1, GLPK_SULIK ;  C3MP45, GLPK_SULIL ;  C3MUZ1, GLPK_SULIM ;
DR   C3NAM2, GLPK_SULIY ;  Q67Q63, GLPK_SYMTH ;  P74260, GLPK_SYNY3 ;
DR   Q9WX53, GLPK_THEAQ ;  Q9X6C9, GLPK_THEBO ;  C5A1M3, GLPK_THEGJ ;
DR   A8F679, GLPK_THELT ;  B6YT00, GLPK_THEON ;  B0K754, GLPK_THEP3 ;
DR   B0K643, GLPK_THEPX ;  O66131, GLPK_THETH ;  Q8R8J4, GLPK_THETN ;
DR   Q73LE9, GLPK_TREDE ;  Q10Y19, GLPK_TRIEI ;  Q9NJP9, GLPK_TRYBB ;
DR   C5CSQ9, GLPK_VARPS ;  A1WKB4, GLPK_VEREI ;  A5EZR2, GLPK_VIBC3 ;
DR   Q9KLJ9, GLPK_VIBCH ;  C3LW10, GLPK_VIBCM ;  Q5E0Z0, GLPK_VIBF1 ;
DR   B5ET10, GLPK_VIBFM ;  A7N1R1, GLPK_VIBHB ;  Q87M72, GLPK_VIBPA ;
DR   B7VQ85, GLPK_VIBSL ;  Q8DBM6, GLPK_VIBVU ;  Q7MI93, GLPK_VIBVY ;
DR   Q8PQG7, GLPK_XANAC ;  Q3BYR0, GLPK_XANC5 ;  Q4UZR8, GLPK_XANC8 ;
DR   B0RMN0, GLPK_XANCB ;  Q8PDI0, GLPK_XANCP ;  A7IJ56, GLPK_XANP2 ;
DR   B2I618, GLPK_XYLF2 ;  Q9PB76, GLPK_XYLFA ;  B0U3F2, GLPK_XYLFM ;
DR   Q87BZ2, GLPK_XYLFT ;  P32190, GLPK_YEAST ;
//
ID   2.7.1.31
DE   Glycerate kinase.
CA   ATP + (R)-glycerate = ADP + 3-phospho-(R)-glycerate.
DR   Q2KJF7, GLCTK_BOVIN;  Q08BL7, GLCTK_DANRE;  Q9VQC4, GLCTK_DROME;
DR   Q8IVS8, GLCTK_HUMAN;  Q9BE01, GLCTK_MACFA;  Q8QZY2, GLCTK_MOUSE;
DR   Q0VGK3, GLCTK_RAT  ;  P77364, GLXK1_ECOLI;  P23524, GLXK2_ECOLI;
DR   Q9XBL1, GLXK_BACC1 ;  Q9Z9P2, GLXK_BACHD ;  P42100, GLXK_BACSU ;
DR   P44507, GLXK_HAEIN ;  P57098, GLXK_NEIMA ;  P57099, GLXK_NEIMB ;
DR   Q944I4, GLYK_ARATH ;
//
ID   2.7.1.32
DE   Choline kinase.
CA   ATP + choline = ADP + O-phosphocholine.
CC   -!- Ethanolamine and its methyl and ethyl derivatives can also act as
CC       acceptors.
DR   P35790, CHKA_HUMAN ;  O54804, CHKA_MOUSE ;  Q01134, CHKA_RAT   ;
DR   Q9Y259, CHKB_HUMAN ;  O55229, CHKB_MOUSE ;  O54783, CHKB_RAT   ;
DR   P46558, KICB1_CAEEL;  P46559, KICB2_CAEEL;  P46560, KICB3_CAEEL;
DR   Q10276, KICH_SCHPO ;  P20485, KICH_YEAST ;
//
ID   2.7.1.33
DE   Pantothenate kinase.
AN   ATP:pantothenate 4'-phosphotransferase.
AN   D-pantothenate kinase.
AN   Pantothenate kinase (phosphorylating).
AN   Pantothenic acid kinase.
CA   ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate.
DR   Q5F5C8, BICOA_NEIG1;  Q9JWI7, BICOA_NEIMA;  Q9JXF1, BICOA_NEIMB;
DR   A3N2G1, COAA_ACTP2 ;  B3GYJ4, COAA_ACTP7 ;  B0BRA6, COAA_ACTPJ ;
DR   A6VKH8, COAA_ACTSZ ;  B9JG63, COAA_AGRRK ;  Q8UJ92, COAA_AGRT5 ;
DR   B9JXX1, COAA_AGRVS ;  A1R8P8, COAA_ARTAT ;  A8HYS9, COAA_AZOC5 ;
DR   A7Z6C4, COAA_BACA2 ;  Q9K8X7, COAA_BACHD ;  Q5WEY6, COAA_BACSK ;
DR   P54556, COAA_BACSU ;  A1UU59, COAA_BARBK ;  Q89WM2, COAA_BRAJA ;
DR   A5E8E3, COAA_BRASB ;  A4YJV7, COAA_BRASO ;  C0Z7P4, COAA_BREBN ;
DR   B2S986, COAA_BRUA1 ;  Q2YQY6, COAA_BRUA2 ;  Q57AH1, COAA_BRUAB ;
DR   A9M9S1, COAA_BRUC2 ;  C0RFX5, COAA_BRUMB ;  P63808, COAA_BRUME ;
DR   A5VT45, COAA_BRUO2 ;  B0CJI8, COAA_BRUSI ;  P63809, COAA_BRUSU ;
DR   A8AKV0, COAA_CITK8 ;  A5CU73, COAA_CLAM3 ;  B0RD37, COAA_CLAMS ;
DR   C3PFC1, COAA_CORA7 ;  Q6NI48, COAA_CORDI ;  Q8FQR2, COAA_COREF ;
DR   A4QCW5, COAA_CORGB ;  Q8NRQ2, COAA_CORGL ;  Q4JU68, COAA_CORJK ;
DR   B6J596, COAA_COXB1 ;  B6J2J7, COAA_COXB2 ;  A9KD67, COAA_COXBN ;
DR   A9NAJ3, COAA_COXBR ;  Q83EV9, COAA_COXBU ;  A7ZUJ0, COAA_ECO24 ;
DR   B7UNV0, COAA_ECO27 ;  B7MIW5, COAA_ECO45 ;  B7LA72, COAA_ECO55 ;
DR   P0A6I5, COAA_ECO57 ;  B7NR61, COAA_ECO7I ;  B7MR65, COAA_ECO81 ;
DR   B7M726, COAA_ECO8A ;  C5A0R9, COAA_ECOBW ;  B1XBY1, COAA_ECODH ;
DR   A8A778, COAA_ECOHS ;  A1AIF2, COAA_ECOK1 ;  Q0TA86, COAA_ECOL5 ;
DR   P0A6I4, COAA_ECOL6 ;  P0A6I3, COAA_ECOLI ;  B7NFR9, COAA_ECOLU ;
DR   B1LNT0, COAA_ECOSM ;  Q1R5X9, COAA_ECOUT ;  A4W599, COAA_ENT38 ;
DR   Q839J7, COAA_ENTFA ;  A7MQP3, COAA_ENTS8 ;  Q6DAN8, COAA_ERWCT ;
DR   B2VG89, COAA_ERWT9 ;  B7LUM3, COAA_ESCF3 ;  Q7VPK9, COAA_HAEDU ;
DR   P44793, COAA_HAEIN ;  Q0I1U8, COAA_HAES1 ;  B0UV22, COAA_HAES2 ;
DR   C4K6Z7, COAA_HAMD5 ;  B5XYG3, COAA_KLEP3 ;  A6TGN1, COAA_KLEP7 ;
DR   Q03PP4, COAA_LACBA ;  Q036Y4, COAA_LACC3 ;  B3W953, COAA_LACCB ;
DR   B2GEA0, COAA_LACF3 ;  Q9CFM3, COAA_LACLA ;  A2RK41, COAA_LACLM ;
DR   Q02YD2, COAA_LACLS ;  Q88Y75, COAA_LACPL ;  A5VLY5, COAA_LACRD ;
DR   B2G996, COAA_LACRJ ;  Q1WRY7, COAA_LACS1 ;  Q38ZE2, COAA_LACSS ;
DR   Q6AD31, COAA_LEIXX ;  Q92D94, COAA_LISIN ;  C1L1J5, COAA_LISMC ;
DR   Q721P1, COAA_LISMF ;  B8DEL2, COAA_LISMH ;  Q8Y8I0, COAA_LISMO ;
DR   A0AH37, COAA_LISW6 ;  Q65QG5, COAA_MANSM ;  Q11CK5, COAA_MESSB ;
DR   B1MKN0, COAA_MYCA9 ;  P63811, COAA_MYCBO ;  A1KHN2, COAA_MYCBP ;
DR   C1AM86, COAA_MYCBT ;  A4T9A9, COAA_MYCGI ;  B8ZSH3, COAA_MYCLB ;
DR   Q9X795, COAA_MYCLE ;  B2HT62, COAA_MYCMM ;  Q73WG0, COAA_MYCPA ;
DR   A0R2V9, COAA_MYCS2 ;  A3Q4Q8, COAA_MYCSJ ;  A1UKP2, COAA_MYCSK ;
DR   Q1B4E6, COAA_MYCSS ;  A5U1D9, COAA_MYCTA ;  P63810, COAA_MYCTU ;
DR   A0PKS1, COAA_MYCUA ;  A1TE33, COAA_MYCVP ;  Q1D9X8, COAA_MYXXD ;
DR   Q1QRW8, COAA_NITHX ;  Q3SWF3, COAA_NITWN ;  Q5YQ72, COAA_NOCFA ;
DR   A1SF33, COAA_NOCSJ ;  A6WX50, COAA_OCHA4 ;  B6JCG7, COAA_OLICO ;
DR   A7HSG6, COAA_PARL1 ;  P57967, COAA_PASMU ;  C6DHQ6, COAA_PECCP ;
DR   Q7MYE7, COAA_PHOLL ;  Q6A6T7, COAA_PROAC ;  A1T0P0, COAA_PSYIN ;
DR   B3PWH7, COAA_RHIE6 ;  Q2KE63, COAA_RHIEC ;  Q1MNG0, COAA_RHIL3 ;
DR   Q98CS9, COAA_RHILO ;  B5ZV89, COAA_RHILW ;  Q92TB5, COAA_RHIME ;
DR   C3MBB9, COAA_RHISN ;  C1A2X7, COAA_RHOE4 ;  C1AYH1, COAA_RHOOB ;
DR   Q2J338, COAA_RHOP2 ;  Q07UR1, COAA_RHOP5 ;  Q6ND01, COAA_RHOPA ;
DR   Q21CJ9, COAA_RHOPB ;  Q13E42, COAA_RHOPS ;  B3Q953, COAA_RHOPT ;
DR   Q0S4A2, COAA_RHOSR ;  B5F0V8, COAA_SALA4 ;  Q57H79, COAA_SALCH ;
DR   B5FPY5, COAA_SALDC ;  B5QXR5, COAA_SALEP ;  B5RFK9, COAA_SALG2 ;
DR   B4TCR5, COAA_SALHS ;  B4T0Y0, COAA_SALNS ;  Q5PK80, COAA_SALPA ;
DR   A9N0I2, COAA_SALPB ;  C0Q2Q8, COAA_SALPC ;  B5BJP4, COAA_SALPK ;
DR   B4TQI6, COAA_SALSV ;  Q8Z318, COAA_SALTI ;  Q9L9K3, COAA_SALTY ;
DR   A8G8D9, COAA_SERP5 ;  A1S203, COAA_SHEAM ;  B8EBM0, COAA_SHEB2 ;
DR   A3DA75, COAA_SHEB5 ;  A6WHR3, COAA_SHEB8 ;  A9KW87, COAA_SHEB9 ;
DR   Q12SX3, COAA_SHEDO ;  Q089R9, COAA_SHEFN ;  B0TM27, COAA_SHEHH ;
DR   A3Q967, COAA_SHELP ;  Q8EK83, COAA_SHEON ;  A8GYW1, COAA_SHEPA ;
DR   A4YBZ8, COAA_SHEPC ;  B8CNB7, COAA_SHEPW ;  A0KRK9, COAA_SHESA ;
DR   A8G1G2, COAA_SHESH ;  Q0HNV3, COAA_SHESM ;  Q0I0C1, COAA_SHESR ;
DR   A1RE99, COAA_SHESW ;  B1KMZ8, COAA_SHEWM ;  B2TWG4, COAA_SHIB3 ;
DR   Q31U19, COAA_SHIBS ;  Q32AF0, COAA_SHIDS ;  Q83PC5, COAA_SHIFL ;
DR   Q3YV06, COAA_SHISS ;  A6UEK1, COAA_SINMW ;  Q2NWS4, COAA_SODGM ;
DR   A9FRP1, COAA_SORC5 ;  Q3K1D6, COAA_STRA1 ;  P63812, COAA_STRA3 ;
DR   P63813, COAA_STRA5 ;  Q82DL5, COAA_STRAW ;  O86779, COAA_STRCO ;
DR   C0M9A7, COAA_STRE4 ;  B4U2S2, COAA_STREM ;  A8AX56, COAA_STRGC ;
DR   Q8DU31, COAA_STRMU ;  Q99ZH1, COAA_STRP1 ;  Q04L73, COAA_STRP2 ;
DR   P0DA40, COAA_STRP3 ;  B5E3L1, COAA_STRP4 ;  Q5XBZ4, COAA_STRP6 ;
DR   C1C6H3, COAA_STRP7 ;  Q8P0V9, COAA_STRP8 ;  Q1JBK2, COAA_STRPB ;
DR   Q1JLI4, COAA_STRPC ;  Q1JGM0, COAA_STRPD ;  Q1J6D9, COAA_STRPF ;
DR   A2REA6, COAA_STRPG ;  B1IB08, COAA_STRPI ;  B8ZNP1, COAA_STRPJ ;
DR   Q48TD0, COAA_STRPM ;  Q97RH6, COAA_STRPN ;  P0DA41, COAA_STRPQ ;
DR   B5XLR5, COAA_STRPZ ;  Q8DQC7, COAA_STRR6 ;  A4W1L8, COAA_STRS2 ;
DR   C0MG55, COAA_STRS7 ;  A3CMP3, COAA_STRSV ;  A4VVB5, COAA_STRSY ;
DR   Q5M079, COAA_STRT1 ;  Q5M4T8, COAA_STRT2 ;  Q03L30, COAA_STRTD ;
DR   C1CDI6, COAA_STRZJ ;  C1CJS8, COAA_STRZP ;  C1CS52, COAA_STRZT ;
DR   Q47LM9, COAA_THEFY ;  Q9KV38, COAA_VIBCH ;  Q8DD30, COAA_VIBVU ;
DR   Q7MGQ9, COAA_VIBVY ;  A7IHN7, COAA_XANP2 ;  A1JIH1, COAA_YERE8 ;
DR   A7FNJ3, COAA_YERP3 ;  Q1C2D3, COAA_YERPA ;  B2K103, COAA_YERPB ;
DR   Q8ZAN6, COAA_YERPE ;  A9R361, COAA_YERPG ;  Q1CN90, COAA_YERPN ;
DR   A4TR20, COAA_YERPP ;  Q66FR1, COAA_YERPS ;  B1JJI8, COAA_YERPY ;
DR   Q81PB2, COAW_BACAN ;  B7JSQ5, COAW_BACC0 ;  Q736G1, COAW_BACC1 ;
DR   B7IKP3, COAW_BACC2 ;  B7H5Z8, COAW_BACC4 ;  Q81C81, COAW_BACCR ;
DR   Q63A51, COAW_BACCZ ;  Q6HHK0, COAW_BACHK ;  Q8EN08, COAW_OCEIH ;
DR   Q2FEZ8, COAW_STAA3 ;  Q2FWC7, COAW_STAA8 ;  Q2YUM3, COAW_STAAB ;
DR   Q5HE70, COAW_STAAC ;  Q99SC8, COAW_STAAM ;  Q7A4D4, COAW_STAAN ;
DR   Q6GEU5, COAW_STAAR ;  Q6G7I0, COAW_STAAS ;  Q8NVG0, COAW_STAAW ;
DR   Q5HM92, COAW_STAEQ ;  Q8CRM3, COAW_STAES ;  Q4L811, COAW_STAHJ ;
DR   Q49Z76, COAW_STAS1 ;  Q14JW3, COAX1_FRAT1;  Q2A4C9, COAX1_FRATH;
DR   Q0BMQ8, COAX1_FRATO;  Q5NIG0, COAX1_FRATT;  Q67JI5, COAX1_SYMTH;
DR   Q14GK8, COAX2_FRAT1;  Q2A1V2, COAX2_FRATH;  Q0BKJ6, COAX2_FRATO;
DR   Q5NF55, COAX2_FRATT;  Q67JI4, COAX2_SYMTH;  A9NGI4, COAX_ACHLI ;
DR   A1TUS2, COAX_ACIAC ;  Q6FDW7, COAX_ACIAD ;  B7GZ77, COAX_ACIB3 ;
DR   B7I784, COAX_ACIB5 ;  B2HUI9, COAX_ACIBC ;  Q1IVF9, COAX_ACIBL ;
DR   B0VU08, COAX_ACIBS ;  A3M2T7, COAX_ACIBT ;  B0V8C7, COAX_ACIBY ;
DR   A0LRC9, COAX_ACIC1 ;  C1F227, COAX_ACIC5 ;  A5FX23, COAX_ACICJ ;
DR   B9MCN0, COAX_ACIET ;  A1W3F9, COAX_ACISJ ;  B2UQS1, COAX_AKKM8 ;
DR   Q0VSN1, COAX_ALCBS ;  Q0ABJ2, COAX_ALHEH ;  A6TWN2, COAX_ALKMQ ;
DR   A8MLU1, COAX_ALKOO ;  B8J561, COAX_ANAD2 ;  Q2IKH9, COAX_ANADE ;
DR   A7HAE1, COAX_ANADF ;  B9KHW8, COAX_ANAMF ;  Q5PBF7, COAX_ANAMM ;
DR   Q2GJ76, COAX_ANAPZ ;  B4UJZ9, COAX_ANASK ;  Q3MC63, COAX_ANAVT ;
DR   O67753, COAX_AQUAE ;  Q5P2L1, COAX_AROAE ;  B6YQ14, COAX_AZOPC ;
DR   A1K3E5, COAX_AZOSB ;  C1DKJ6, COAX_AZOVD ;  A7Z0J3, COAX_BACA2 ;
DR   C3P9L2, COAX_BACAA ;  C3LJ39, COAX_BACAC ;  A0R8D8, COAX_BACAH ;
DR   Q81VX4, COAX_BACAN ;  B7JK73, COAX_BACC0 ;  Q73FE2, COAX_BACC1 ;
DR   B7ISX6, COAX_BACC2 ;  C1ESZ6, COAX_BACC3 ;  B7HJ05, COAX_BACC4 ;
DR   B7HPX7, COAX_BACC7 ;  A7GJX8, COAX_BACCN ;  Q81J81, COAX_BACCR ;
DR   Q63HD3, COAX_BACCZ ;  Q5LGL2, COAX_BACFN ;  Q64XF4, COAX_BACFR ;
DR   Q9KGH5, COAX_BACHD ;  Q6HPV1, COAX_BACHK ;  Q65PF1, COAX_BACLD ;
DR   Q5WLV5, COAX_BACSK ;  P37564, COAX_BACSU ;  Q89ZL1, COAX_BACTN ;
DR   A6L3F8, COAX_BACV8 ;  A9VN79, COAX_BACWK ;  Q6MHI0, COAX_BDEBA ;
DR   B8DTP8, COAX_BIFA0 ;  A1A0M5, COAX_BIFAA ;  B3DT97, COAX_BIFLD ;
DR   Q8G558, COAX_BIFLO ;  B7GUD5, COAX_BIFLS ;  Q2L1G9, COAX_BORA1 ;
DR   Q0SMY2, COAX_BORAP ;  O88005, COAX_BORBR ;  O51477, COAX_BORBU ;
DR   Q660Z6, COAX_BORGA ;  B2S0M7, COAX_BORHD ;  A9IH79, COAX_BORPD ;
DR   Q45338, COAX_BORPE ;  C0ZHH0, COAX_BREBN ;  B1YNP3, COAX_BURA4 ;
DR   Q1BT63, COAX_BURCA ;  B1JZB2, COAX_BURCC ;  A0KAX6, COAX_BURCH ;
DR   B4E9P3, COAX_BURCJ ;  Q0BBG3, COAX_BURCM ;  A9AEF0, COAX_BURM1 ;
DR   A3MR36, COAX_BURM7 ;  A2S5X1, COAX_BURM9 ;  Q62MZ8, COAX_BURMA ;
DR   A1V034, COAX_BURMS ;  A3NQV8, COAX_BURP0 ;  A3N559, COAX_BURP6 ;
DR   B2JKK7, COAX_BURP8 ;  B2SWX0, COAX_BURPP ;  Q63XZ2, COAX_BURPS ;
DR   Q39CH4, COAX_BURS3 ;  Q2T1M2, COAX_BURTA ;  A4JI88, COAX_BURVG ;
DR   Q146G6, COAX_BURXL ;  A7I3S0, COAX_CAMHC ;  Q0PBB6, COAX_CAMJE ;
DR   Q5HW73, COAX_CAMJR ;  Q3A9L7, COAX_CARHZ ;  Q9A6Z1, COAX_CAUCR ;
DR   B0SZ33, COAX_CAUSK ;  B3PK21, COAX_CELJU ;  Q3AR95, COAX_CHLCH ;
DR   B3QMM1, COAX_CHLP8 ;  Q8KCK7, COAX_CHLTE ;  Q1R0I9, COAX_CHRSD ;
DR   Q7P0S9, COAX_CHRVO ;  Q97EB4, COAX_CLOAB ;  A7FZA9, COAX_CLOB1 ;
DR   C3KVU3, COAX_CLOB6 ;  A6LPL2, COAX_CLOB8 ;  B2UXU6, COAX_CLOBA ;
DR   B2TI22, COAX_CLOBB ;  A5I7P8, COAX_CLOBH ;  C1FNC9, COAX_CLOBJ ;
DR   B1IGY0, COAX_CLOBK ;  A7GJB7, COAX_CLOBL ;  B1KTC5, COAX_CLOBM ;
DR   B8I4H0, COAX_CLOCE ;  Q181F7, COAX_CLOD6 ;  B9DY69, COAX_CLOK1 ;
DR   A5N4K7, COAX_CLOK5 ;  A0PXN1, COAX_CLONN ;  Q0TMI4, COAX_CLOP1 ;
DR   Q8XHL5, COAX_CLOPE ;  A9KHE4, COAX_CLOPH ;  Q0SQ83, COAX_CLOPS ;
DR   Q899H1, COAX_CLOTE ;  A3DIK9, COAX_CLOTH ;  Q47UY4, COAX_COLP3 ;
DR   Q477E8, COAX_CUPPJ ;  B2AG52, COAX_CUPTR ;  Q11Q02, COAX_CYTH3 ;
DR   Q479J6, COAX_DECAR ;  Q3Z9C7, COAX_DEHE1 ;  A5FS34, COAX_DEHSB ;
DR   Q3ZZH1, COAX_DEHSC ;  Q1IXJ0, COAX_DEIGD ;  Q9RX54, COAX_DEIRA ;
DR   B8FMB1, COAX_DESAA ;  C0QHQ9, COAX_DESAH ;  B8J468, COAX_DESDA ;
DR   Q316Q1, COAX_DESDG ;  B8FZE5, COAX_DESHD ;  Q251N7, COAX_DESHY ;
DR   A8ZZH7, COAX_DESOH ;  Q6AKW8, COAX_DESPS ;  Q72F93, COAX_DESVH ;
DR   B8DMB1, COAX_DESVM ;  A1VGV6, COAX_DESVV ;  A5EVK4, COAX_DICNV ;
DR   B8E2Z9, COAX_DICTD ;  A8LIV9, COAX_DINSH ;  Q3YSS7, COAX_EHRCJ ;
DR   Q2GFQ3, COAX_EHRCR ;  Q5FFD0, COAX_EHRRG ;  Q5HBZ7, COAX_EHRRW ;
DR   B2KBD0, COAX_ELUMP ;  Q2NA81, COAX_ERYLH ;  C4Z9L7, COAX_EUBR3 ;
DR   B1YGQ7, COAX_EXIS2 ;  C4KZT8, COAX_EXISA ;  A7HM80, COAX_FERNB ;
DR   B0S218, COAX_FINM2 ;  A5FK26, COAX_FLAJ1 ;  A6H2B4, COAX_FLAPJ ;
DR   Q0RB90, COAX_FRAAA ;  Q2J4R7, COAX_FRASC ;  A8LCM4, COAX_FRASN ;
DR   Q8RFE4, COAX_FUSNN ;  B5EF22, COAX_GEOBB ;  Q5L3T0, COAX_GEOKA ;
DR   B3E7Q7, COAX_GEOLS ;  Q39U59, COAX_GEOMG ;  B9LZI6, COAX_GEOSF ;
DR   Q74BU2, COAX_GEOSL ;  C6E791, COAX_GEOSM ;  C5D391, COAX_GEOSW ;
DR   A4IJE6, COAX_GEOTN ;  A5G5C1, COAX_GEOUR ;  Q7NCI5, COAX_GLOVI ;
DR   Q5FUV0, COAX_GLUOX ;  Q0BSL7, COAX_GRABC ;  A0M5N3, COAX_GRAFK ;
DR   Q2S8Z5, COAX_HAHCH ;  A1WVD8, COAX_HALHL ;  B8D075, COAX_HALOH ;
DR   Q7VJU3, COAX_HELHP ;  Q1CT10, COAX_HELPH ;  Q9ZKY6, COAX_HELPJ ;
DR   O25533, COAX_HELPY ;  A4G9B3, COAX_HERAR ;  Q0C1C9, COAX_HYPNA ;
DR   Q5QY78, COAX_IDILO ;  A6T332, COAX_JANMA ;  Q28T47, COAX_JANSC ;
DR   C5CFU0, COAX_KOSOT ;  C1D6Y0, COAX_LARHH ;  Q1MS79, COAX_LAWIP ;
DR   Q5X6J2, COAX_LEGPA ;  A5IG02, COAX_LEGPC ;  Q5ZX22, COAX_LEGPH ;
DR   Q5WXZ6, COAX_LEGPL ;  Q04V79, COAX_LEPBJ ;  Q04Y97, COAX_LEPBL ;
DR   B1Y6R5, COAX_LEPCP ;  Q72NP0, COAX_LEPIC ;  Q8F7V9, COAX_LEPIN ;
DR   Q92F54, COAX_LISIN ;  C1KYF4, COAX_LISMC ;  Q724J2, COAX_LISMF ;
DR   B8DGK4, COAX_LISMH ;  Q8YAC5, COAX_LISMO ;  A0AF20, COAX_LISW6 ;
DR   Q2W3J9, COAX_MAGSA ;  A0L7P3, COAX_MAGSM ;  A1TYI2, COAX_MARAV ;
DR   Q0APX5, COAX_MARMM ;  A6W3A7, COAX_MARMS ;  Q607I0, COAX_METCA ;
DR   Q1GZJ0, COAX_METFK ;  B3DWU5, COAX_METI4 ;  A2SLA5, COAX_METPP ;
DR   Q2RM55, COAX_MOOTA ;  A0QA95, COAX_MYCA1 ;  B1MGV8, COAX_MYCA9 ;
DR   Q7TW42, COAX_MYCBO ;  A1KPT5, COAX_MYCBP ;  C1AI58, COAX_MYCBT ;
DR   A4T5N5, COAX_MYCGI ;  B8ZU51, COAX_MYCLB ;  Q9CD56, COAX_MYCLE ;
DR   B2HJ44, COAX_MYCMM ;  Q6KH54, COAX_MYCMO ;  Q743Y3, COAX_MYCPA ;
DR   Q8EUB0, COAX_MYCPE ;  A0R579, COAX_MYCS2 ;  Q4A743, COAX_MYCS5 ;
DR   A3Q6Y3, COAX_MYCSJ ;  A1UMH8, COAX_MYCSK ;  Q1B2M0, COAX_MYCSS ;
DR   A5U8S5, COAX_MYCTA ;  O06282, COAX_MYCTU ;  A0PV48, COAX_MYCUA ;
DR   A1TG33, COAX_MYCVP ;  Q1D4U7, COAX_MYXXD ;  Q0AJF4, COAX_NITEC ;
DR   Q82S93, COAX_NITEU ;  Q2Y796, COAX_NITMU ;  Q3JEM4, COAX_NITOC ;
DR   Q5Z2U1, COAX_NOCFA ;  A1SDX1, COAX_NOCSJ ;  Q8YQD7, COAX_NOSS1 ;
DR   Q2G601, COAX_NOVAD ;  Q8EU15, COAX_OCEIH ;  A1B477, COAX_PARDP ;
DR   Q3A346, COAX_PELCD ;  Q3B314, COAX_PELLD ;  A1ALR6, COAX_PELPD ;
DR   A5D5P9, COAX_PELTS ;  Q4FM76, COAX_PELUB ;  C0QU76, COAX_PERMH ;
DR   A9BIX4, COAX_PETMO ;  B4RC03, COAX_PHEZH ;  A1VT30, COAX_POLNA ;
DR   Q124V5, COAX_POLSJ ;  B2RKY9, COAX_PORG3 ;  Q7MWY2, COAX_PORGI ;
DR   Q48D21, COAX_PSE14 ;  Q15NP1, COAX_PSEA6 ;  A6UZH2, COAX_PSEA7 ;
DR   B7V628, COAX_PSEA8 ;  Q02T96, COAX_PSEAB ;  Q9HWC1, COAX_PSEAE ;
DR   C3K2Z1, COAX_PSEFS ;  Q3IJV0, COAX_PSEHT ;  A4XZA6, COAX_PSEMY ;
DR   A5VXN1, COAX_PSEP1 ;  Q3K5X2, COAX_PSEPF ;  B0KK51, COAX_PSEPG ;
DR   Q88QQ0, COAX_PSEPK ;  B1JE18, COAX_PSEPW ;  Q889Y6, COAX_PSESM ;
DR   Q4ZMM9, COAX_PSEU2 ;  Q4FUX4, COAX_PSYA2 ;  Q1QDX4, COAX_PSYCK ;
DR   Q1LSB6, COAX_RALME ;  Q8Y2M4, COAX_RALSO ;  Q7UVH5, COAX_RHOBA ;
DR   B6ISW6, COAX_RHOCS ;  C0ZPL5, COAX_RHOE4 ;  Q21SD6, COAX_RHOFD ;
DR   C1BA77, COAX_RHOOB ;  Q2RU25, COAX_RHORT ;  A3PIY7, COAX_RHOS1 ;
DR   Q3J3E2, COAX_RHOS4 ;  A4WU16, COAX_RHOS5 ;  B9KQX9, COAX_RHOSK ;
DR   Q0S8D3, COAX_RHOSR ;  A7NF27, COAX_ROSCS ;  Q163S6, COAX_ROSDO ;
DR   A5UVB3, COAX_ROSS1 ;  Q1AU02, COAX_RUBXD ;  Q21MA1, COAX_SACD2 ;
DR   A4F6T2, COAX_SACEN ;  A8M8E8, COAX_SALAI ;  Q2S560, COAX_SALRD ;
DR   Q5LPT8, COAX_SILPO ;  Q1GIM1, COAX_SILST ;  Q01PF4, COAX_SOLUE ;
DR   Q1GTL4, COAX_SPHAL ;  A5VAN5, COAX_SPHWW ;  Q82EC5, COAX_STRAW ;
DR   Q9X8N6, COAX_STRCO ;  B1VSI6, COAX_STRGG ;  B4ST96, COAX_STRM5 ;
DR   B2FIV8, COAX_STRMK ;  Q30S65, COAX_SULDN ;  B2V5N9, COAX_SULSY ;
DR   Q2LUQ6, COAX_SYNAS ;  Q31M81, COAX_SYNE7 ;  A0LFP6, COAX_SYNFM ;
DR   Q2JXC9, COAX_SYNJA ;  Q2JLD5, COAX_SYNJB ;  Q5MZP5, COAX_SYNP6 ;
DR   Q0B0N9, COAX_SYNWW ;  P74045, COAX_SYNY3 ;  C5BPP8, COAX_TERTT ;
DR   B7ID76, COAX_THEAB ;  Q8DJS3, COAX_THEEB ;  Q47KV7, COAX_THEFY ;
DR   A6LMR3, COAX_THEM4 ;  Q9WZY5, COAX_THEMA ;  B0KC42, COAX_THEP3 ;
DR   B0K5B1, COAX_THEPX ;  B9L0J2, COAX_THERP ;  B1LCE8, COAX_THESQ ;
DR   Q72IX3, COAX_THET2 ;  Q5SIJ5, COAX_THET8 ;  Q8R7M2, COAX_THETN ;
DR   Q31E86, COAX_THICR ;  Q3SLJ6, COAX_THIDA ;  O83446, COAX_TREPA ;
DR   B2S328, COAX_TREPS ;  B1GZU1, COAX_UNCTG ;  A1WJV9, COAX_VEREI ;
DR   Q7MS38, COAX_WOLSU ;  Q8PFG5, COAX_XANAC ;  Q3BN23, COAX_XANC5 ;
DR   Q4UPF9, COAX_XANC8 ;  B0RXV6, COAX_XANCB ;  Q8P3Y1, COAX_XANCP ;
DR   Q2P8I1, COAX_XANOM ;  B2SS98, COAX_XANOP ;  Q5H5T7, COAX_XANOR ;
DR   B2I5C0, COAX_XYLF2 ;  Q9PCI4, COAX_XYLFA ;  Q87CJ5, COAX_XYLFT ;
DR   Q5NLB9, COAX_ZYMMO ;  O80765, PANK1_ARATH;  Q8TE04, PANK1_HUMAN;
DR   Q8K4K6, PANK1_MOUSE;  Q8L5Y9, PANK2_ARATH;  Q9BZ23, PANK2_HUMAN;
DR   Q08DA5, PANK3_BOVIN;  Q9H999, PANK3_HUMAN;  Q8R2W9, PANK3_MOUSE;
DR   Q9NVE7, PANK4_HUMAN;  Q4R4U1, PANK4_MACFA;  Q80YV4, PANK4_MOUSE;
DR   Q5R5F8, PANK4_PONAB;  Q923S8, PANK4_RAT  ;  O74962, PANK_SCHPO ;
DR   Q04430, PANK_YEAST ;
//
ID   2.7.1.34
DE   Pantetheine kinase.
CA   ATP + pantetheine = ADP + pantetheine 4'-phosphate.
//
ID   2.7.1.35
DE   Pyridoxal kinase.
AN   Pyridoxamine kinase.
AN   Pyridoxine kinase.
AN   Vitamin B(6) kinase.
AN   Vitamin B6 kinase.
CA   ATP + pyridoxal = ADP + pyridoxal 5'-phosphate.
CC   -!- Pyridoxine, pyridoxamine and various derivatives can also act as
CC       acceptors.
DR   P39988, BUD16_YEAST;  P53727, BUD17_YEAST;  Q8W1X2, PDXK_ARATH ;
DR   P39610, PDXK_BACSU ;  Q2L1P5, PDXK_BORA1 ;  Q7WII1, PDXK_BORBR ;
DR   Q7W6K7, PDXK_BORPA ;  Q7VYK4, PDXK_BORPE ;  Q0II59, PDXK_BOVIN ;
DR   O01824, PDXK_CAEEL ;  Q55EK9, PDXK_DICDI ;  A7ZPL9, PDXK_ECO24 ;
DR   B7UGB9, PDXK_ECO27 ;  B7MHS2, PDXK_ECO45 ;  B7LCG3, PDXK_ECO55 ;
DR   Q8XBL0, PDXK_ECO57 ;  B5YZW5, PDXK_ECO5E ;  B7NPV5, PDXK_ECO7I ;
DR   B7MY71, PDXK_ECO81 ;  B7M6S8, PDXK_ECO8A ;  C4ZVU9, PDXK_ECOBW ;
DR   B1XA89, PDXK_ECODH ;  A8A2R4, PDXK_ECOHS ;  A1ADT5, PDXK_ECOK1 ;
DR   Q0TF48, PDXK_ECOL5 ;  Q8FFB5, PDXK_ECOL6 ;  B1IX53, PDXK_ECOLC ;
DR   P40191, PDXK_ECOLI ;  B7N609, PDXK_ECOLU ;  B6I4Z5, PDXK_ECOSE ;
DR   B1LML3, PDXK_ECOSM ;  Q1R8V2, PDXK_ECOUT ;  B7LL66, PDXK_ESCF3 ;
DR   O00764, PDXK_HUMAN ;  Q8K183, PDXK_MOUSE ;  O46560, PDXK_PIG   ;
DR   Q1LFU5, PDXK_RALME ;  O35331, PDXK_RAT   ;  Q57LS3, PDXK_SALCH ;
DR   Q5PNC8, PDXK_SALPA ;  Q8Z4W1, PDXK_SALTI ;  P40192, PDXK_SALTY ;
DR   P82197, PDXK_SHEEP ;  B2TX08, PDXK_SHIB3 ;  Q32DD5, PDXK_SHIDS ;
DR   Q83K78, PDXK_SHIFL ;  Q3YZC3, PDXK_SHISS ;  Q5HI96, PDXK_STAAC ;
DR   Q5HRG7, PDXK_STAEQ ;  Q8CTQ7, PDXK_STAES ;  O83153, PDXK_TREPA ;
DR   A3N2D3, PDXY_ACTP2 ;  B3H2H2, PDXY_ACTP7 ;  A6VNE5, PDXY_ACTSZ ;
DR   Q1BXQ7, PDXY_BURCA ;  Q62LP6, PDXY_BURMA ;  Q3JQA6, PDXY_BURP1 ;
DR   B2JCI0, PDXY_BURP8 ;  Q63SC2, PDXY_BURPS ;  Q39I40, PDXY_BURS3 ;
DR   Q2SXQ4, PDXY_BURTA ;  Q141E8, PDXY_BURXL ;  Q6NG19, PDXY_CORDI ;
DR   Q1J237, PDXY_DEIGD ;  Q9RYX0, PDXY_DEIRA ;  Q8X649, PDXY_ECO57 ;
DR   Q0THJ1, PDXY_ECOL5 ;  Q8FH89, PDXY_ECOL6 ;  P77150, PDXY_ECOLI ;
DR   Q1RBF9, PDXY_ECOUT ;  Q6D5V1, PDXY_ERWCT ;  Q0BSF0, PDXY_GRABC ;
DR   A5UA83, PDXY_HAEIE ;  P44690, PDXY_HAEIN ;  Q0I3D2, PDXY_HAES1 ;
DR   B0UUD2, PDXY_HAES2 ;  Q6AFC1, PDXY_LEIXX ;  Q65UE8, PDXY_MANSM ;
DR   Q9CNY1, PDXY_PASMU ;  Q7N3W7, PDXY_PHOLL ;  Q6LP62, PDXY_PHOPR ;
DR   Q51892, PDXY_PROMI ;  Q48BL6, PDXY_PSE14 ;  A6VEZ4, PDXY_PSEA7 ;
DR   B7V753, PDXY_PSEA8 ;  Q02DJ3, PDXY_PSEAB ;  Q9HT57, PDXY_PSEAE ;
DR   Q1I2L8, PDXY_PSEE4 ;  Q4K3F6, PDXY_PSEF5 ;  C3K4G7, PDXY_PSEFS ;
DR   A5WB73, PDXY_PSEP1 ;  Q3K4B8, PDXY_PSEPF ;  B0KR83, PDXY_PSEPG ;
DR   Q88C26, PDXY_PSEPK ;  B1JFM7, PDXY_PSEPW ;  Q87TZ6, PDXY_PSESM ;
DR   Q4ZL75, PDXY_PSEU2 ;  Q1AYE5, PDXY_RUBXD ;  Q57PI7, PDXY_SALCH ;
DR   Q5PIK8, PDXY_SALPA ;  Q8Z6Q3, PDXY_SALTI ;  Q8ZPM8, PDXY_SALTY ;
DR   Q320Z3, PDXY_SHIBS ;  Q32FD7, PDXY_SHIDS ;  Q83KY1, PDXY_SHIFL ;
DR   Q3Z1Z2, PDXY_SHISS ;  Q5E345, PDXY_VIBF1 ;  A7N5Q6, PDXY_VIBHB ;
DR   Q87FP6, PDXY_VIBPA ;  Q8D4Q2, PDXY_VIBVU ;  Q7MGA4, PDXY_VIBVY ;
DR   Q1C792, PDXY_YERPA ;  Q7CIR8, PDXY_YERPE ;  Q1CIM6, PDXY_YERPN ;
DR   Q66A50, PDXY_YERPS ;  O14242, YELB_SCHPO ;  O74860, YQ9A_SCHPO ;
//
ID   2.7.1.36
DE   Mevalonate kinase.
CA   ATP + (R)-mevalonate = ADP + (R)-5-phosphomevalonate.
CC   -!- CTP, GTP and UTP can also act as donors.
PR   PROSITE; PDOC00545;
DR   Q9Y946, KIME_AERPE ;  P46086, KIME_ARATH ;  O27995, KIME_ARCFU ;
DR   Q5E9T8, KIME_BOVIN ;  Q86AG7, KIME_DICDI ;  Q03426, KIME_HUMAN ;
DR   Q58487, KIME_METJA ;  Q50559, KIME_METTH ;  Q9R008, KIME_MOUSE ;
DR   Q9V187, KIME_PYRAB ;  Q8U0F3, KIME_PYRFU ;  O59291, KIME_PYRHO ;
DR   Q5JJC6, KIME_PYRKO ;  P17256, KIME_RAT   ;  Q09780, KIME_SCHPO ;
DR   C5A7L8, KIME_THEGJ ;  B6YST1, KIME_THEON ;  C6A3T5, KIME_THESM ;
DR   P07277, KIME_YEAST ;
//
ID   2.7.1.37
DE   Transferred entry: 2.7.11.1.
//
ID   2.7.1.38
DE   Transferred entry: 2.7.11.19.
//
ID   2.7.1.39
DE   Homoserine kinase.
CA   ATP + L-homoserine = ADP + O-phospho-L-homoserine.
PR   PROSITE; PDOC00545;
DR   A5FZ25, KHSE_ACICJ ;  Q9YA72, KHSE_AERPE ;  B9JAQ3, KHSE_AGRRK ;
DR   Q8UHA8, KHSE_AGRT5 ;  B9JT39, KHSE_AGRVS ;  B6EKY7, KHSE_ALISL ;
DR   A6TKS7, KHSE_ALKMQ ;  A8MI61, KHSE_ALKOO ;  B9ML57, KHSE_ANATD ;
DR   Q3M9C9, KHSE_ANAVT ;  O67332, KHSE_AQUAE ;  A8EWD5, KHSE_ARCB4 ;
DR   A8HX69, KHSE_AZOC5 ;  A7Z8E0, KHSE_BACA2 ;  C3P7F5, KHSE_BACAA ;
DR   C3L5M2, KHSE_BACAC ;  A0RCX4, KHSE_BACAH ;  Q81RS0, KHSE_BACAN ;
DR   B7JKG2, KHSE_BACC0 ;  Q739T5, KHSE_BACC1 ;  B7IT85, KHSE_BACC2 ;
DR   C1ER94, KHSE_BACC3 ;  B7HJ93, KHSE_BACC4 ;  B7HNB7, KHSE_BACC7 ;
DR   A7GNV5, KHSE_BACCN ;  B9IXW1, KHSE_BACCQ ;  Q81EK4, KHSE_BACCR ;
DR   Q63CI8, KHSE_BACCZ ;  Q9K7E4, KHSE_BACHD ;  Q6HJZ3, KHSE_BACHK ;
DR   Q65FC4, KHSE_BACLD ;  A8FH24, KHSE_BACP2 ;  Q5WDT6, KHSE_BACSK ;
DR   P04948, KHSE_BACSU ;  A9VQT3, KHSE_BACWK ;  Q6G4C4, KHSE_BARHE ;
DR   A9IQR2, KHSE_BART1 ;  B2IHG2, KHSE_BEII9 ;  Q7VQL6, KHSE_BLOFL ;
DR   Q493S9, KHSE_BLOPB ;  Q89UU4, KHSE_BRAJA ;  A5EAL1, KHSE_BRASB ;
DR   A4Z217, KHSE_BRASO ;  B2S9X0, KHSE_BRUA1 ;  Q2YMI4, KHSE_BRUA2 ;
DR   Q57EP5, KHSE_BRUAB ;  A9M8Z9, KHSE_BRUC2 ;  C0RHI3, KHSE_BRUMB ;
DR   Q8YFR2, KHSE_BRUME ;  A5VP46, KHSE_BRUO2 ;  B0CKG1, KHSE_BRUSI ;
DR   Q8G256, KHSE_BRUSU ;  B8D8Z2, KHSE_BUCA5 ;  O66132, KHSE_BUCAI ;
DR   Q8K9V0, KHSE_BUCAP ;  B8D797, KHSE_BUCAT ;  P59568, KHSE_BUCBP ;
DR   Q057U7, KHSE_BUCCC ;  B1Z151, KHSE_BURA4 ;  Q1BLX6, KHSE_BURCA ;
DR   B1K3U1, KHSE_BURCC ;  A0AYX8, KHSE_BURCH ;  B4EN17, KHSE_BURCJ ;
DR   Q0BAN2, KHSE_BURCM ;  A9ANP0, KHSE_BURM1 ;  A3MBA7, KHSE_BURM7 ;
DR   A2S0L3, KHSE_BURM9 ;  Q62DV9, KHSE_BURMA ;  A1UYM9, KHSE_BURMS ;
DR   A3P7Z0, KHSE_BURP0 ;  Q3JK86, KHSE_BURP1 ;  A3NMH8, KHSE_BURP6 ;
DR   B2JQI5, KHSE_BURP8 ;  B2T9I7, KHSE_BURPP ;  Q63JD9, KHSE_BURPS ;
DR   Q393M6, KHSE_BURS3 ;  Q2T7P9, KHSE_BURTA ;  A4JLS0, KHSE_BURVG ;
DR   Q13RY4, KHSE_BURXL ;  A4XI71, KHSE_CALS8 ;  A7ZC67, KHSE_CAMC1 ;
DR   A0RQZ6, KHSE_CAMFF ;  A7I3V2, KHSE_CAMHC ;  A8FJT9, KHSE_CAMJ8 ;
DR   A7H1L3, KHSE_CAMJD ;  Q9PIZ3, KHSE_CAMJE ;  A1VXL7, KHSE_CAMJJ ;
DR   Q5HX32, KHSE_CAMJR ;  B9KEU8, KHSE_CAMLR ;  Q92209, KHSE_CANAL ;
DR   Q3AAV5, KHSE_CARHZ ;  B8H4W6, KHSE_CAUCN ;  Q9A342, KHSE_CAUCR ;
DR   B0T024, KHSE_CAUSK ;  B3EL38, KHSE_CHLPB ;  A1BJF6, KHSE_CHLPD ;
DR   B3QWX6, KHSE_CHLT3 ;  Q8KAW7, KHSE_CHLTE ;  A8ALV4, KHSE_CITK8 ;
DR   A5CQ46, KHSE_CLAM3 ;  Q97JN8, KHSE_CLOAB ;  A7FUE5, KHSE_CLOB1 ;
DR   C3KW44, KHSE_CLOB6 ;  A6LSZ4, KHSE_CLOB8 ;  B2UX33, KHSE_CLOBA ;
DR   B2TPC7, KHSE_CLOBB ;  A5I2A9, KHSE_CLOBH ;  C1FNA5, KHSE_CLOBJ ;
DR   B1ILR0, KHSE_CLOBK ;  A7GDW6, KHSE_CLOBL ;  B1KS25, KHSE_CLOBM ;
DR   A5N6I0, KHSE_CLOK5 ;  A0Q3H1, KHSE_CLONN ;  Q891L4, KHSE_CLOTE ;
DR   C3PFP1, KHSE_CORA7 ;  Q6NHU3, KHSE_CORDI ;  Q8FQ44, KHSE_COREF ;
DR   A4QDE5, KHSE_CORGB ;  P07128, KHSE_CORGL ;  Q4JUI5, KHSE_CORJK ;
DR   C4LJM9, KHSE_CORK4 ;  B1VFW6, KHSE_CORU7 ;  Q0K848, KHSE_CUPNH ;
DR   Q474D4, KHSE_CUPPJ ;  B3R5F6, KHSE_CUPTR ;  B1WP79, KHSE_CYAA5 ;
DR   Q9RRU5, KHSE_DEIRA ;  B8FU92, KHSE_DESHD ;  Q24XU1, KHSE_DESHY ;
DR   A7ZH92, KHSE_ECO24 ;  B7UI48, KHSE_ECO27 ;  B7M9R6, KHSE_ECO45 ;
DR   B7L4C8, KHSE_ECO55 ;  Q8XA82, KHSE_ECO57 ;  B5YY97, KHSE_ECO5E ;
DR   B7NHA6, KHSE_ECO7I ;  B7N2U2, KHSE_ECO81 ;  B7M0A0, KHSE_ECO8A ;
DR   C4ZPT0, KHSE_ECOBW ;  B1XBC8, KHSE_ECODH ;  A7ZVW2, KHSE_ECOHS ;
DR   A1A756, KHSE_ECOK1 ;  Q0TLY6, KHSE_ECOL5 ;  Q8FLD8, KHSE_ECOL6 ;
DR   B1IRH0, KHSE_ECOLC ;  P00547, KHSE_ECOLI ;  B7N7M8, KHSE_ECOLU ;
DR   B6HZ00, KHSE_ECOSE ;  B1LFT4, KHSE_ECOSM ;  Q1RGK1, KHSE_ECOUT ;
DR   C5B7K5, KHSE_EDWI9 ;  Q831T0, KHSE_ENTFA ;  A7MIJ7, KHSE_ENTS8 ;
DR   Q6D0A9, KHSE_ERWCT ;  B2VH20, KHSE_ERWT9 ;  B7LWR1, KHSE_ESCF3 ;
DR   P04947, KHSE_FREDI ;  Q7NLJ6, KHSE_GLOVI ;  A9HS91, KHSE_GLUDA ;
DR   Q5FUH8, KHSE_GLUOX ;  Q0BQX8, KHSE_GRABC ;  Q4QP96, KHSE_HAEI8 ;
DR   A5UB54, KHSE_HAEIE ;  A5UFQ1, KHSE_HAEIG ;  P44504, KHSE_HAEIN ;
DR   Q0I3T3, KHSE_HAES1 ;  B0UWP6, KHSE_HAES2 ;  B9LS04, KHSE_HALLT ;
DR   Q5UXG4, KHSE_HALMA ;  B8CW89, KHSE_HALOH ;  B0R6D7, KHSE_HALS3 ;
DR   Q9HP55, KHSE_HALSA ;  Q18F42, KHSE_HALWD ;  C4K7E6, KHSE_HAMD5 ;
DR   Q7VHF4, KHSE_HELHP ;  Q9ZM48, KHSE_HELPJ ;  O25690, KHSE_HELPY ;
DR   A4G1V8, KHSE_HERAR ;  Q0C3L9, KHSE_HYPNA ;  A6SUR4, KHSE_JANMA ;
DR   B5Y254, KHSE_KLEP3 ;  A6T4E3, KHSE_KLEP7 ;  Q5FJS7, KHSE_LACAC ;
DR   B2GCV0, KHSE_LACF3 ;  Q043C5, KHSE_LACGA ;  Q9CGD7, KHSE_LACLA ;
DR   P52991, KHSE_LACLC ;  A2RKV6, KHSE_LACLM ;  Q02Z13, KHSE_LACLS ;
DR   Q88Z08, KHSE_LACPL ;  Q6AG73, KHSE_LEIXX ;  B1MYF2, KHSE_LEUCK ;
DR   Q03Y28, KHSE_LEUMM ;  Q927U8, KHSE_LISIN ;  C1KYW2, KHSE_LISMC ;
DR   Q71WN3, KHSE_LISMF ;  B8DBG4, KHSE_LISMH ;  Q8Y4A6, KHSE_LISMO ;
DR   A0ALN0, KHSE_LISW6 ;  B1HYT4, KHSE_LYSSC ;  Q2W9A8, KHSE_MAGSA ;
DR   Q65RV1, KHSE_MANSM ;  Q11KC6, KHSE_MESSB ;  A6UV93, KHSE_META3 ;
DR   Q9RAM6, KHSE_METFK ;  O32378, KHSE_METGL ;  Q58504, KHSE_METJA ;
DR   Q8TYG6, KHSE_METKA ;  A4FZP2, KHSE_METM5 ;  A9A802, KHSE_METM6 ;
DR   A6VIT5, KHSE_METM7 ;  Q6M0H5, KHSE_METMP ;  B8ILM3, KHSE_METNO ;
DR   B1ZC86, KHSE_METPB ;  B1M3E0, KHSE_METRJ ;  B0UKH0, KHSE_METS4 ;
DR   B8EPM3, KHSE_METSB ;  A6URT1, KHSE_METVS ;  Q2RIX1, KHSE_MOOTA ;
DR   B1MLU6, KHSE_MYCA9 ;  P65225, KHSE_MYCBO ;  B8ZR28, KHSE_MYCLB ;
DR   P45836, KHSE_MYCLE ;  Q73X44, KHSE_MYCPA ;  A0R219, KHSE_MYCS2 ;
DR   A3Q3C9, KHSE_MYCSJ ;  A1UK02, KHSE_MYCSK ;  Q1B535, KHSE_MYCSS ;
DR   P65224, KHSE_MYCTU ;  A0PUL4, KHSE_MYCUA ;  A1TD73, KHSE_MYCVP ;
DR   Q3INF0, KHSE_NATPD ;  B2A8C9, KHSE_NATTJ ;  B9L6E6, KHSE_NAUPA ;
DR   Q9JWE5, KHSE_NEIMA ;  Q4W557, KHSE_NEIMB ;  Q0AHY7, KHSE_NITEC ;
DR   Q82UL3, KHSE_NITEU ;  Q1QH29, KHSE_NITHX ;  Q2YBJ8, KHSE_NITMU ;
DR   A6Q225, KHSE_NITSB ;  Q3SP50, KHSE_NITWN ;  Q5Z0Z5, KHSE_NOCFA ;
DR   B2J7E8, KHSE_NOSP7 ;  Q8YZV9, KHSE_NOSS1 ;  Q8ET01, KHSE_OCEIH ;
DR   A6WWG7, KHSE_OCHA4 ;  B6JJ40, KHSE_OLICO ;  A7HQX5, KHSE_PARL1 ;
DR   Q9CPD3, KHSE_PASMU ;  C6DF18, KHSE_PECCP ;  C0QQC5, KHSE_PERMH ;
DR   A9BGN7, KHSE_PETMO ;  B4R8T4, KHSE_PHEZH ;  Q7N8Z5, KHSE_PHOLL ;
DR   Q6LUP9, KHSE_PHOPR ;  Q6L1U1, KHSE_PICTO ;  A1VMB2, KHSE_POLNA ;
DR   Q6A8B2, KHSE_PROAC ;  A3PBW9, KHSE_PROM0 ;  A2C153, KHSE_PROM1 ;
DR   A8G3W1, KHSE_PROM2 ;  A2CAU0, KHSE_PROM3 ;  A2BVQ8, KHSE_PROM5 ;
DR   Q31BT9, KHSE_PROM9 ;  Q7VBM6, KHSE_PROMA ;  Q7V8D0, KHSE_PROMM ;
DR   Q7V289, KHSE_PROMP ;  Q46LV5, KHSE_PROMT ;  A4SGN0, KHSE_PROVI ;
DR   B7V732, KHSE_PSEA8 ;  Q02DL4, KHSE_PSEAB ;  P29364, KHSE_PSEAE ;
DR   Q9UZV7, KHSE_PYRAB ;  Q8ZZX3, KHSE_PYRAE ;  A3MT44, KHSE_PYRCJ ;
DR   Q8U1Z9, KHSE_PYRFU ;  O58814, KHSE_PYRHO ;  A1RQK6, KHSE_PYRIL ;
DR   Q5JH53, KHSE_PYRKO ;  Q1LK22, KHSE_RALME ;  B2U942, KHSE_RALPJ ;
DR   Q8XX83, KHSE_RALSO ;  B3PSC0, KHSE_RHIE6 ;  Q2KBL3, KHSE_RHIEC ;
DR   Q1MKH7, KHSE_RHIL3 ;  Q985W2, KHSE_RHILO ;  B5ZSW0, KHSE_RHILW ;
DR   Q92RG1, KHSE_RHIME ;  C3MHK2, KHSE_RHISN ;  C1A1Z3, KHSE_RHOE4 ;
DR   C1AW13, KHSE_RHOOB ;  Q2J0F9, KHSE_RHOP2 ;  Q07J29, KHSE_RHOP5 ;
DR   Q6N1Y2, KHSE_RHOPA ;  Q20Z33, KHSE_RHOPB ;  Q131J1, KHSE_RHOPS ;
DR   B3Q6U2, KHSE_RHOPT ;  Q2RPU7, KHSE_RHORT ;  B5F6C2, KHSE_SALA4 ;
DR   A9MR86, KHSE_SALAR ;  Q57TQ2, KHSE_SALCH ;  B5FH97, KHSE_SALDC ;
DR   B5R5H5, KHSE_SALEP ;  B5REZ9, KHSE_SALG2 ;  B4TIA4, KHSE_SALHS ;
DR   B4T6C6, KHSE_SALNS ;  Q5PDM3, KHSE_SALPA ;  A9MXH1, KHSE_SALPB ;
DR   C0Q4E3, KHSE_SALPC ;  B5BLG9, KHSE_SALPK ;  B4TVY5, KHSE_SALSV ;
DR   P65227, KHSE_SALTI ;  P65226, KHSE_SALTY ;  O43056, KHSE_SCHPO ;
DR   P27722, KHSE_SERMA ;  A8G9K0, KHSE_SERP5 ;  B2U219, KHSE_SHIB3 ;
DR   Q326L9, KHSE_SHIBS ;  Q32KB5, KHSE_SHIDS ;  Q0T8I5, KHSE_SHIF8 ;
DR   Q83MH9, KHSE_SHIFL ;  Q3Z611, KHSE_SHISS ;  A6U6V4, KHSE_SINMW ;
DR   Q2NVZ5, KHSE_SODGM ;  Q02AL5, KHSE_SOLUE ;  A7X1Y2, KHSE_STAA1 ;
DR   A6U1F0, KHSE_STAA2 ;  Q2FHA3, KHSE_STAA3 ;  Q2FYV2, KHSE_STAA8 ;
DR   A5ISL2, KHSE_STAA9 ;  Q2YXT6, KHSE_STAAB ;  Q5HG90, KHSE_STAAC ;
DR   A6QGN2, KHSE_STAAE ;  P65228, KHSE_STAAM ;  P65229, KHSE_STAAN ;
DR   Q6GH76, KHSE_STAAR ;  Q6G9M8, KHSE_STAAS ;  A8Z213, KHSE_STAAT ;
DR   Q8NWV8, KHSE_STAAW ;  B9DP91, KHSE_STACT ;  Q5HPL2, KHSE_STAEQ ;
DR   Q8CSQ2, KHSE_STAES ;  Q4L639, KHSE_STAHJ ;  Q49XB7, KHSE_STAS1 ;
DR   Q3K0X8, KHSE_STRA1 ;  Q8E546, KHSE_STRA3 ;  Q8DZI2, KHSE_STRA5 ;
DR   Q82J66, KHSE_STRAW ;  Q9ADB2, KHSE_STRCO ;  C0MA57, KHSE_STRE4 ;
DR   A8AWE1, KHSE_STRGC ;  Q8DUG4, KHSE_STRMU ;  Q04JY7, KHSE_STRP2 ;
DR   B5E5F6, KHSE_STRP4 ;  C1C7W1, KHSE_STRP7 ;  B1ICG1, KHSE_STRPI ;
DR   B8ZKK9, KHSE_STRPJ ;  P0A3L7, KHSE_STRPN ;  B2IQH7, KHSE_STRPS ;
DR   P0A3L8, KHSE_STRR6 ;  A4W0S2, KHSE_STRS2 ;  C0MEX3, KHSE_STRS7 ;
DR   A3CMQ4, KHSE_STRSV ;  A4VUI0, KHSE_STRSY ;  Q5M117, KHSE_STRT1 ;
DR   Q5M5K5, KHSE_STRT2 ;  Q03LY7, KHSE_STRTD ;  B9DRZ0, KHSE_STRU0 ;
DR   C1CEU9, KHSE_STRZJ ;  C1CL69, KHSE_STRZP ;  C1CQZ4, KHSE_STRZT ;
DR   Q4JA46, KHSE_SULAC ;  Q30SS8, KHSE_SULDN ;  C3N0N3, KHSE_SULIA ;
DR   C4KK76, KHSE_SULIK ;  C3MK52, KHSE_SULIL ;  C3MU21, KHSE_SULIM ;
DR   C3NM92, KHSE_SULIN ;  C3N8M1, KHSE_SULIY ;  A6QBQ7, KHSE_SULNB ;
DR   Q97W70, KHSE_SULSO ;  Q975A7, KHSE_SULTO ;  Q67LA5, KHSE_SYMTH ;
DR   Q31N99, KHSE_SYNE7 ;  B1XLE7, KHSE_SYNP2 ;  Q5N5W2, KHSE_SYNP6 ;
DR   A5GJT4, KHSE_SYNPW ;  Q7U659, KHSE_SYNPX ;  A5GSI7, KHSE_SYNR3 ;
DR   Q0I8Z9, KHSE_SYNS3 ;  Q3AYC9, KHSE_SYNS9 ;  Q3AKU3, KHSE_SYNSC ;
DR   Q0AXC8, KHSE_SYNWW ;  P73646, KHSE_SYNY3 ;  Q9HKR6, KHSE_THEAC ;
DR   Q8DI27, KHSE_THEEB ;  C5A1P1, KHSE_THEGJ ;  Q9WZ15, KHSE_THEMA ;
DR   B1YDP4, KHSE_THENV ;  A5IJN0, KHSE_THEP1 ;  Q72IV3, KHSE_THET2 ;
DR   Q5SIH5, KHSE_THET8 ;  Q8R711, KHSE_THETN ;  Q979X5, KHSE_THEVO ;
DR   Q117D0, KHSE_TRIEI ;  Q0W2X4, KHSE_UNCMA ;  A5F5R9, KHSE_VIBC3 ;
DR   Q9KPK4, KHSE_VIBCH ;  C3LQD5, KHSE_VIBCM ;  Q5E2Y4, KHSE_VIBF1 ;
DR   B5FAK1, KHSE_VIBFM ;  Q87SC9, KHSE_VIBPA ;  B7VJ36, KHSE_VIBSL ;
DR   Q8DEP3, KHSE_VIBVU ;  Q7MNR4, KHSE_VIBVY ;  Q7M7X6, KHSE_WOLSU ;
DR   Q4UU32, KHSE_XANC8 ;  B0RSK6, KHSE_XANCB ;  Q8P9Q0, KHSE_XANCP ;
DR   A7IHV6, KHSE_XANP2 ;  B2I5Y6, KHSE_XYLF2 ;  Q9PBC0, KHSE_XYLFA ;
DR   B0U3B8, KHSE_XYLFM ;  Q87C24, KHSE_XYLFT ;  P17423, KHSE_YEAST ;
DR   A1JJC7, KHSE_YERE8 ;  A7FMF2, KHSE_YERP3 ;  Q1C0K9, KHSE_YERPA ;
DR   B2K3L2, KHSE_YERPB ;  Q8ZIN5, KHSE_YERPE ;  A9R025, KHSE_YERPG ;
DR   Q1CMW6, KHSE_YERPN ;  A4TQG9, KHSE_YERPP ;  Q66ET8, KHSE_YERPS ;
DR   B1JL13, KHSE_YERPY ;  O69015, KHSE_ZYMMO ;
//
ID   2.7.1.40
DE   Pyruvate kinase.
AN   Phosphoenol transphosphorylase.
AN   Phosphoenolpyruvate kinase.
CA   ATP + pyruvate = ADP + phosphoenolpyruvate.
CC   -!- UTP, GTP, CTP, ITP and dATP can also act as donors.
CC   -!- Also phosphorylates hydroxylamine and fluoride in the presence of
CC       CO(2).
PR   PROSITE; PDOC00101;
DR   Q43117, KPYA_RICCO ;  Q40545, KPYA_TOBAC ;  O65595, KPYC_ARATH ;
DR   P22200, KPYC_SOLTU ;  Q42806, KPYC_SOYBN ;  Q42954, KPYC_TOBAC ;
DR   P55964, KPYG_RICCO ;  Q40546, KPYG_TOBAC ;  P70789, KPYK1_AGRVI;
DR   Q6FIS9, KPYK1_CANGA;  P0AD62, KPYK1_ECO57;  P0AD61, KPYK1_ECOLI;
DR   O30853, KPYK1_PHOLE;  Q8Z6K2, KPYK1_SALTI;  P77983, KPYK1_SALTY;
DR   Q55863, KPYK1_SYNY3;  P30615, KPYK1_TRYBB;  P00549, KPYK1_YEAST;
DR   Q44473, KPYK2_AGRVI;  Q6FV12, KPYK2_CANGA;  P21599, KPYK2_ECOLI;
DR   Q8ZNW0, KPYK2_SALTY;  P73534, KPYK2_SYNY3;  P30616, KPYK2_TRYBB;
DR   P52489, KPYK2_YEAST;  Q9YEU2, KPYK_AERPE ;  O94122, KPYK_AGABI ;
DR   Q759A9, KPYK_ASHGO ;  Q12669, KPYK_ASPNG ;  P51181, KPYK_BACLI ;
DR   P51182, KPYK_BACPY ;  P80885, KPYK_BACSU ;  O51323, KPYK_BORBU ;
DR   P57404, KPYK_BUCAI ;  Q8K9M3, KPYK_BUCAP ;  Q89AI8, KPYK_BUCBP ;
DR   P46614, KPYK_CANAL ;  P00548, KPYK_CHICK ;  Q9PK61, KPYK_CHLMU ;
DR   Q9Z984, KPYK_CHLPN ;  B0B7Q0, KPYK_CHLT2 ;  P0CE21, KPYK_CHLTR ;
DR   O08309, KPYK_CLOAB ;  P81344, KPYK_CLOPA ;  Q46289, KPYK_CLOPE ;
DR   Q8FP04, KPYK_COREF ;  Q46078, KPYK_CORGL ;  Q6BS75, KPYK_DEBHA ;
DR   Q54RF5, KPYK_DICDI ;  O62619, KPYK_DROME ;  O44006, KPYK_EIMTE ;
DR   P22360, KPYK_EMENI ;  Q8SQP0, KPYK_ENCCU ;  Q02499, KPYK_GEOSE ;
DR   P43924, KPYK_HAEIN ;  Q875M9, KPYK_KLULA ;  P34038, KPYK_LACDE ;
DR   Q07637, KPYK_LACLA ;  Q04668, KPYK_LEIBR ;  Q27686, KPYK_LEIME ;
DR   O05118, KPYK_METEA ;  Q57572, KPYK_METJA ;  P47458, KPYK_MYCGE ;
DR   P94939, KPYK_MYCIT ;  P78031, KPYK_MYCPN ;  O06134, KPYK_MYCTU ;
DR   Q7RVA8, KPYK_NEUCR ;  Q8ZYE0, KPYK_PYRAE ;  Q875Z9, KPYK_SACCA ;
DR   Q875S4, KPYK_SACKL ;  Q10208, KPYK_SCHPO ;  P19680, KPYK_SPICI ;
DR   Q2FG40, KPYK_STAA3 ;  Q2FXM9, KPYK_STAA8 ;  Q2YTE3, KPYK_STAAB ;
DR   Q5HF76, KPYK_STAAC ;  Q99TG5, KPYK_STAAM ;  Q7A559, KPYK_STAAN ;
DR   Q6GG09, KPYK_STAAR ;  Q6G8M9, KPYK_STAAS ;  Q7A0N4, KPYK_STAAW ;
DR   Q5HNK7, KPYK_STAEQ ;  Q8CS69, KPYK_STAES ;  Q4L739, KPYK_STAHJ ;
DR   Q49YC7, KPYK_STAS1 ;  P32044, KPYK_THEAC ;  Q56301, KPYK_THELI ;
DR   Q9WY51, KPYK_THEMA ;  P31865, KPYK_TRIRE ;  Q27788, KPYK_TRYBO ;
DR   Q92122, KPYK_XENLA ;  P30614, KPYK_YARLI ;  P11979, KPYM_FELCA ;
DR   P14618, KPYM_HUMAN ;  P52480, KPYM_MOUSE ;  Q5NVN0, KPYM_PONAB ;
DR   P11974, KPYM_RABIT ;  P11980, KPYM_RAT   ;  Q29536, KPYR_CANFA ;
DR   P30613, KPYR_HUMAN ;  P53657, KPYR_MOUSE ;  P12928, KPYR_RAT   ;
//
ID   2.7.1.41
DE   Glucose-1-phosphate phosphodismutase.
CA   2 D-glucose 1-phosphate = D-glucose + D-glucose 1,6-bisphosphate.
//
ID   2.7.1.42
DE   Riboflavin phosphotransferase.
CA   Alpha-D-glucose 1-phosphate + riboflavin = D-glucose + FMN.
//
ID   2.7.1.43
DE   Glucuronokinase.
CA   ATP + D-glucuronate = ADP + 1-phospho-alpha-D-glucuronate.
DR   Q93ZC9, GLAK1_ARATH;  Q9LY82, GLAK2_ARATH;
//
ID   2.7.1.44
DE   Galacturonokinase.
CA   ATP + D-galacturonate = ADP + 1-phospho-alpha-D-galacturonate.
DR   Q8VYG2, GALAK_ARATH;
//
ID   2.7.1.45
DE   2-dehydro-3-deoxygluconokinase.
AN   2-keto-3-deoxygluconokinase.
AN   3-deoxy-2-oxo-D-gluconate kinase.
AN   KDG kinase.
CA   ATP + 2-dehydro-3-deoxy-D-gluconate = ADP + 6-phospho-2-dehydro-3-deoxy-
CA   D-gluconate.
PR   PROSITE; PDOC00504;
DR   P50845, KDGK_BACSU ;  P45416, KDGK_DICD3 ;  P37647, KDGK_ECOLI ;
DR   P44482, KDGK_HAEIN ;
//
ID   2.7.1.46
DE   L-arabinokinase.
CA   ATP + L-arabinose = ADP + beta-L-arabinose 1-phosphate.
DR   O23461, ARAK_ARATH ;
//
ID   2.7.1.47
DE   D-ribulokinase.
CA   ATP + D-ribulose = ADP + D-ribulose 5-phosphate.
//
ID   2.7.1.48
DE   Uridine kinase.
AN   Uridine monophosphokinase.
CA   (1) ATP + uridine = ADP + UMP.
CA   (2) ATP + cytidine = ADP + CMP.
CC   -!- Cytidine can act as acceptor.
CC   -!- GTP and ITP can act as donors.
DR   Q12084, DAS2_YEAST ;  Q6PA79, UCK1A_XENLA;  Q6GPD9, UCK1B_XENLA;
DR   Q0P5A4, UCK1_BOVIN ;  Q66I71, UCK1_DANRE ;  Q9HA47, UCK1_HUMAN ;
DR   Q4R4K2, UCK1_MACFA ;  P52623, UCK1_MOUSE ;  Q7SYM0, UCK2A_DANRE;
DR   Q7ZV79, UCK2B_DANRE;  Q9BZX2, UCK2_HUMAN ;  Q99PM9, UCK2_MOUSE ;
DR   Q9QYG8, UCK2_RAT   ;  B1H116, UCK2_XENTR ;  Q55EL3, UCKA_DICDI ;
DR   Q8T154, UCKB_DICDI ;  Q54R62, UCKC_DICDI ;  Q9GNF0, UCKD_DICDI ;
DR   Q9NWZ5, UCKL1_HUMAN;  Q17413, UCK_CAEEL  ;  Q9VC99, UCK_DROME  ;
DR   Q9FKS0, UKL1_ARATH ;  Q9LK34, UKL2_ARATH ;  Q8VYB2, UKL3_ARATH ;
DR   O65583, UKL4_ARATH ;  Q9LTY6, UKL5_ARATH ;  O74427, URK1_SCHPO ;
DR   P27515, URK1_YEAST ;  A0KKF8, URK_AERHH  ;  A4SML3, URK_AERS4  ;
DR   B6EIY7, URK_ALISL  ;  A6TR08, URK_ALKMQ  ;  B7GIU0, URK_ANOFW  ;
DR   A7Z727, URK_BACA2  ;  C3P969, URK_BACAA  ;  C3L5Y6, URK_BACAC  ;
DR   A0RIZ3, URK_BACAH  ;  Q81LK8, URK_BACAN  ;  B7JP70, URK_BACC0  ;
DR   Q730F4, URK_BACC1  ;  B7IYN4, URK_BACC2  ;  C1ESS5, URK_BACC3  ;
DR   B7HE15, URK_BACC4  ;  B7HQD8, URK_BACC7  ;  A7GT59, URK_BACCN  ;
DR   B9IYE5, URK_BACCQ  ;  Q817Z5, URK_BACCR  ;  Q634G4, URK_BACCZ  ;
DR   Q9KDD8, URK_BACHD  ;  Q6HDE5, URK_BACHK  ;  Q65GT3, URK_BACLD  ;
DR   A8FFL8, URK_BACP2  ;  O32033, URK_BACSU  ;  A9VI01, URK_BACWK  ;
DR   Q0SPE9, URK_BORAP  ;  Q59190, URK_BORBU  ;  B7J0V4, URK_BORBZ  ;
DR   B5RLM3, URK_BORDL  ;  Q662Z7, URK_BORGA  ;  B2S1K4, URK_BORHD  ;
DR   B5RQJ8, URK_BORRA  ;  A1QYG8, URK_BORT9  ;  C0ZAS6, URK_BREBN  ;
DR   A9WCC8, URK_CHLAA  ;  B8G8N0, URK_CHLAD  ;  Q9Z7H0, URK_CHLPN  ;
DR   B9LED5, URK_CHLSY  ;  C3L140, URK_CLOB6  ;  C1FSX6, URK_CLOBJ  ;
DR   B1IJ68, URK_CLOBK  ;  A7GGE1, URK_CLOBL  ;  B1KXA7, URK_CLOBM  ;
DR   A0Q140, URK_CLONN  ;  Q0TPI4, URK_CLOP1  ;  Q8XJI6, URK_CLOPE  ;
DR   Q0SS52, URK_CLOPS  ;  Q896E3, URK_CLOTE  ;  C1CXN1, URK_DEIDV  ;
DR   Q9RXZ5, URK_DEIRA  ;  P0A8F6, URK_ECO57  ;  P0A8F5, URK_ECOL6  ;
DR   P0A8F4, URK_ECOLI  ;  A4WCB6, URK_ENT38  ;  A7MHG8, URK_ENTS8  ;
DR   Q6D7B4, URK_ERWCT  ;  B2VFR1, URK_ERWT9  ;  B7LV30, URK_ESCF3  ;
DR   Q5KWV3, URK_GEOKA  ;  C5D4Y5, URK_GEOSW  ;  A4IR72, URK_GEOTN  ;
DR   Q7VL27, URK_HAEDU  ;  Q4QP55, URK_HAEI8  ;  A5UB17, URK_HAEIE  ;
DR   A5UFT8, URK_HAEIG  ;  P44533, URK_HAEIN  ;  Q0I2Y9, URK_HAES1  ;
DR   B0UT65, URK_HAES2  ;  Q9HQC9, URK_HALSA  ;  B5XPC8, URK_KLEP3  ;
DR   A6TBG6, URK_KLEP7  ;  A8YU29, URK_LACH4  ;  Q74KI9, URK_LACJO  ;
DR   Q9CF21, URK_LACLA  ;  A2RJB4, URK_LACLM  ;  Q02XK6, URK_LACLS  ;
DR   Q88WR0, URK_LACPL  ;  A5VKU8, URK_LACRD  ;  B2G882, URK_LACRJ  ;
DR   Q1WTY6, URK_LACS1  ;  Q38VV6, URK_LACSS  ;  B1MXP1, URK_LEUCK  ;
DR   Q92BL6, URK_LISIN  ;  C1KVE4, URK_LISMC  ;  Q71ZH3, URK_LISMF  ;
DR   B8DE13, URK_LISMH  ;  Q8Y727, URK_LISMO  ;  A0AIU6, URK_LISW6  ;
DR   B9E6Y9, URK_MACCJ  ;  Q65S71, URK_MANSM  ;  P47622, URK_MYCGE  ;
DR   P75217, URK_MYCPN  ;  Q8EPT5, URK_OCEIH  ;  Q9CM85, URK_PASMU  ;
DR   C6DCI6, URK_PECCP  ;  Q7N6J4, URK_PHOLL  ;  B4ESY8, URK_PROMH  ;
DR   A1SUY9, URK_PSYIN  ;  B5EXV0, URK_SALA4  ;  Q57MN1, URK_SALCH  ;
DR   B5FMU1, URK_SALDC  ;  B5R0B5, URK_SALEP  ;  B5RBW3, URK_SALG2  ;
DR   B4T9T4, URK_SALHS  ;  B4SXV3, URK_SALNS  ;  Q5PDX6, URK_SALPA  ;
DR   A9N7M0, URK_SALPB  ;  C0Q1G0, URK_SALPC  ;  B5BF73, URK_SALPK  ;
DR   B4TNH9, URK_SALSV  ;  P67409, URK_SALTI  ;  P67408, URK_SALTY  ;
DR   A8GC40, URK_SERP5  ;  A1S796, URK_SHEAM  ;  B8E960, URK_SHEB2  ;
DR   A3D5E3, URK_SHEB5  ;  A6WP54, URK_SHEB8  ;  A9L4F4, URK_SHEB9  ;
DR   Q12MJ0, URK_SHEDO  ;  Q081H5, URK_SHEFN  ;  B0TJ03, URK_SHEHH  ;
DR   Q8EDX4, URK_SHEON  ;  A8H3V4, URK_SHEPA  ;  A4Y7K6, URK_SHEPC  ;
DR   B8CPI6, URK_SHEPW  ;  A0KW26, URK_SHESA  ;  Q0HJN4, URK_SHESM  ;
DR   Q0HVY0, URK_SHESR  ;  A1RIY2, URK_SHESW  ;  P0A8F7, URK_SHIFL  ;
DR   Q2NUC7, URK_SODGM  ;  A7X320, URK_STAA1  ;  A6U280, URK_STAA2  ;
DR   Q2FGB5, URK_STAA3  ;  Q2FXW6, URK_STAA8  ;  A5ITD6, URK_STAA9  ;
DR   Q2YT67, URK_STAAB  ;  Q5HFF1, URK_STAAC  ;  A6QHF2, URK_STAAE  ;
DR   P67410, URK_STAAM  ;  P67411, URK_STAAN  ;  Q6GG92, URK_STAAR  ;
DR   Q6G8V8, URK_STAAS  ;  A8Z4E9, URK_STAAT  ;  P67412, URK_STAAW  ;
DR   B9DNJ4, URK_STACT  ;  Q5HNT9, URK_STAEQ  ;  Q8CSB2, URK_STAES  ;
DR   Q4L6V8, URK_STAHJ  ;  Q49Y49, URK_STAS1  ;  Q3K1N1, URK_STRA1  ;
DR   Q8E5Y5, URK_STRA3  ;  Q8E0A8, URK_STRA5  ;  C0M9M0, URK_STRE4  ;
DR   B4U220, URK_STREM  ;  A8AWT2, URK_STRGC  ;  Q8DTG1, URK_STRMU  ;
DR   P67415, URK_STRP1  ;  Q04KA9, URK_STRP2  ;  P0DH36, URK_STRP3  ;
DR   B5E4U6, URK_STRP4  ;  Q5XBI8, URK_STRP6  ;  C1C7H7, URK_STRP7  ;
DR   Q8P0F8, URK_STRP8  ;  A2RDZ9, URK_STRPG  ;  B1IC10, URK_STRPI  ;
DR   B8ZQ77, URK_STRPJ  ;  P67413, URK_STRPN  ;  P0DH37, URK_STRPQ  ;
DR   B2IPS2, URK_STRPS  ;  B5XM21, URK_STRPZ  ;  P67414, URK_STRR6  ;
DR   C0MCM8, URK_STRS7  ;  Q5LZ98, URK_STRT1  ;  Q5M3V0, URK_STRT2  ;
DR   Q03K46, URK_STRTD  ;  B9DSN2, URK_STRU0  ;  C1CEH1, URK_STRZJ  ;
DR   C1CKV4, URK_STRZP  ;  C1CR90, URK_STRZT  ;  Q72L53, URK_THET2  ;
DR   Q5SKR5, URK_THET8  ;  C4LEX3, URK_TOLAT  ;  B1AIX1, URK_UREP2  ;
DR   Q9PQF9, URK_UREPA  ;  B5ZBE2, URK_UREU1  ;  Q9KT67, URK_VIBCH  ;
DR   Q5E3Z9, URK_VIBF1  ;  B5FG51, URK_VIBFM  ;  A7MVE7, URK_VIBHB  ;
DR   Q87N09, URK_VIBPA  ;  B7VLX0, URK_VIBSL  ;  Q8D8F4, URK_VIBVU  ;
DR   Q7MM12, URK_VIBVY  ;  A1JTX4, URK_YERE8  ;  A7FJJ4, URK_YERP3  ;
DR   Q1C9T6, URK_YERPA  ;  B2JZK5, URK_YERPB  ;  Q8ZFZ9, URK_YERPE  ;
DR   A9R2M5, URK_YERPG  ;  Q1CGU6, URK_YERPN  ;  A4TKM7, URK_YERPP  ;
DR   Q66C70, URK_YERPS  ;  B1JPY6, URK_YERPY  ;  Q9UTC5, YIDE_SCHPO ;
//
ID   2.7.1.49
DE   Hydroxymethylpyrimidine kinase.
CA   ATP + 4-amino-5-hydroxymethyl-2-methylpyrimidine = ADP + 4-amino-5-
CA   phosphonooxymethyl-2-methylpyrimidine.
CC   -!- CTP, UTP and GTP can act as donors.
DR   Q08224, THI20_YEAST;  O94265, THI21_SCHPO;  Q08975, THI21_YEAST;
DR   O94266, THI22_SCHPO;  O67772, THID_AQUAE ;  O31620, THID_BACSU ;
DR   P76422, THID_ECOLI ;  P44697, THID_HAEIN ;  Q9ZL00, THID_HELPJ ;
DR   O25515, THID_HELPY ;  P66914, THID_MYCBO ;  Q9ZBL1, THID_MYCLE ;
DR   P66913, THID_MYCTU ;  P56904, THID_RHIME ;  P55882, THID_SALTY ;
DR   P66915, THID_STAAM ;  P99124, THID_STAAN ;  Q6GEY2, THID_STAAR ;
DR   Q6G7L7, THID_STAAS ;  Q8NVH3, THID_STAAW ;  Q9ZBR6, THID_STRCO ;
DR   O85786, THID_SYNE7 ;  Q8FTH8, THIED_COREF;  Q8NQH1, THIED_CORGL;
DR   P61422, THIED_GEOSL;  Q9USL6, YJK5_SCHPO ;
//
ID   2.7.1.50
DE   Hydroxyethylthiazole kinase.
CA   ATP + 4-methyl-5-(2-hydroxyethyl)thiazole = ADP + 4-methyl-5-
CA   (2-phosphonooxyethyl)thiazole.
DR   P40386, THI4_SCHPO ;  P41835, THI6_YEAST ;  A7FPT1, THIM1_CLOB1;
DR   C3L062, THIM1_CLOB6;  A5HYZ4, THIM1_CLOBH;  C1FSC2, THIM1_CLOBJ;
DR   B1IEG7, THIM1_CLOBK;  A7GAL1, THIM1_CLOBL;  B1KW01, THIM1_CLOBM;
DR   Q03YX1, THIM1_LEUMM;  Q2NGH3, THIM1_METST;  Q8ESZ2, THIM1_OCEIH;
DR   Q04LH9, THIM1_STRP2;  B5E320, THIM1_STRP4;  C1C666, THIM1_STRP7;
DR   B1IAN9, THIM1_STRPI;  B8ZN14, THIM1_STRPJ;  Q97RS6, THIM1_STRPN;
DR   B2IN99, THIM1_STRPS;  Q8DQK5, THIM1_STRR6;  C1CD69, THIM1_STRZJ;
DR   C1CJG8, THIM1_STRZP;  C1CQI2, THIM1_STRZT;  A7FVR9, THIM2_CLOB1;
DR   C3KZ28, THIM2_CLOB6;  A5I421, THIM2_CLOBH;  C1FR28, THIM2_CLOBJ;
DR   B1IHH3, THIM2_CLOBK;  A7GFJ3, THIM2_CLOBL;  B1KV13, THIM2_CLOBM;
DR   Q03XM8, THIM2_LEUMM;  Q2NGG1, THIM2_METST;  Q8ESJ1, THIM2_OCEIH;
DR   Q04LH2, THIM2_STRP2;  B5E327, THIM2_STRP4;  C1C673, THIM2_STRP7;
DR   B1IAP6, THIM2_STRPI;  B8ZN21, THIM2_STRPJ;  Q97RR9, THIM2_STRPN;
DR   B2INA6, THIM2_STRPS;  Q8DQJ9, THIM2_STRR6;  C1CD76, THIM2_STRZJ;
DR   C1CJH5, THIM2_STRZP;  C1CQI9, THIM2_STRZT;  Q67T51, THIME_SYMTH;
DR   Q6FAS9, THIM_ACIAD ;  B7H160, THIM_ACIB3 ;  B7IAM8, THIM_ACIB5 ;
DR   B2HTR5, THIM_ACIBC ;  B0VM84, THIM_ACIBS ;  A3M6H8, THIM_ACIBT ;
DR   B0V782, THIM_ACIBY ;  A6VPG7, THIM_ACTSZ ;  B9JK65, THIM_AGRRK ;
DR   Q8UAS9, THIM_AGRT5 ;  B2UP55, THIM_AKKM8 ;  B6ERB4, THIM_ALISL ;
DR   A6TMN6, THIM_ALKMQ ;  A8MK93, THIM_ALKOO ;  B7GKQ7, THIM_ANOFW ;
DR   O28204, THIM_ARCFU ;  A7ZA59, THIM_BACA2 ;  C3PBW0, THIM_BACAA ;
DR   C3L626, THIM_BACAC ;  A0R980, THIM_BACAH ;  Q81Z96, THIM_BACAN ;
DR   B7JN71, THIM_BACC0 ;  Q73E73, THIM_BACC1 ;  B7IVS8, THIM_BACC2 ;
DR   C1EVE5, THIM_BACC3 ;  B7H7H4, THIM_BACC4 ;  B7HT69, THIM_BACC7 ;
DR   A7GKR3, THIM_BACCN ;  B9J2L4, THIM_BACCQ ;  Q81IG9, THIM_BACCR ;
DR   Q63GK4, THIM_BACCZ ;  Q9K7L2, THIM_BACHD ;  Q6HP18, THIM_BACHK ;
DR   Q65DJ9, THIM_BACLD ;  A8FIR7, THIM_BACP2 ;  Q5WDW4, THIM_BACSK ;
DR   P39593, THIM_BACSU ;  A9VRN3, THIM_BACWK ;  B8DSX7, THIM_BIFA0 ;
DR   A1A2J2, THIM_BIFAA ;  B3DQ80, THIM_BIFLD ;  Q8G7X0, THIM_BIFLO ;
DR   B7GQ20, THIM_BIFLS ;  C0QWJ2, THIM_BRAHW ;  C0ZGJ5, THIM_BREBN ;
DR   A3P5E2, THIM_BURP0 ;  Q3JME7, THIM_BURP1 ;  A3NJS6, THIM_BURP6 ;
DR   Q63L73, THIM_BURPS ;  Q2T5T2, THIM_BURTA ;  A8M9N5, THIM_CALMQ ;
DR   B9KD06, THIM_CAMLR ;  Q3AE32, THIM_CARHZ ;  A9WDL9, THIM_CHLAA ;
DR   Q5L6R4, THIM_CHLAB ;  B8G7I8, THIM_CHLAD ;  Q824E8, THIM_CHLCV ;
DR   Q253G3, THIM_CHLFF ;  B9LIA5, THIM_CHLSY ;  B3QT42, THIM_CHLT3 ;
DR   A8AEC1, THIM_CITK8 ;  A5CSW0, THIM_CLAM3 ;  B0RGG4, THIM_CLAMS ;
DR   Q97EL4, THIM_CLOAB ;  A6M1W7, THIM_CLOB8 ;  B2UY66, THIM_CLOBA ;
DR   B2TQ14, THIM_CLOBB ;  B8I3J5, THIM_CLOCE ;  Q186F4, THIM_CLOD6 ;
DR   B9E564, THIM_CLOK1 ;  A5N1D3, THIM_CLOK5 ;  A0Q299, THIM_CLONN ;
DR   Q0TQV3, THIM_CLOP1 ;  Q8XKQ7, THIM_CLOPE ;  Q0STA0, THIM_CLOPS ;
DR   Q893Q9, THIM_CLOTE ;  B5Y6I0, THIM_COPPD ;  Q8FTH7, THIM_COREF ;
DR   A4QE51, THIM_CORGB ;  Q8NQH0, THIM_CORGL ;  B8FJW2, THIM_DESAA ;
DR   C0QAT7, THIM_DESAH ;  B1I1S3, THIM_DESAP ;  B8J4C1, THIM_DESDA ;
DR   Q312G9, THIM_DESDG ;  B8FUD3, THIM_DESHD ;  Q24XQ1, THIM_DESHY ;
DR   C4XIJ3, THIM_DESMR ;  A8ZV98, THIM_DESOH ;  Q6AQZ6, THIM_DESPS ;
DR   A4J233, THIM_DESRM ;  Q729I7, THIM_DESVH ;  B8DJ66, THIM_DESVM ;
DR   A1VBV4, THIM_DESVV ;  A5EY60, THIM_DICNV ;  A7ZNS3, THIM_ECO24 ;
DR   B7UFC1, THIM_ECO27 ;  B7MEF9, THIM_ECO45 ;  B7L9X5, THIM_ECO55 ;
DR   Q8X7G3, THIM_ECO57 ;  B5YV51, THIM_ECO5E ;  B7NPM9, THIM_ECO7I ;
DR   B7MWQ4, THIM_ECO81 ;  B7M485, THIM_ECO8A ;  C4ZSI8, THIM_ECOBW ;
DR   B1X7J5, THIM_ECODH ;  A8A1W9, THIM_ECOHS ;  A1ACX0, THIM_ECOK1 ;
DR   Q0TFY8, THIM_ECOL5 ;  Q8FFY0, THIM_ECOL6 ;  B1IYX7, THIM_ECOLC ;
DR   P76423, THIM_ECOLI ;  B7NCD4, THIM_ECOLU ;  B6HYU5, THIM_ECOSE ;
DR   B1LN84, THIM_ECOSM ;  Q1R9W8, THIM_ECOUT ;  A4WCE6, THIM_ENT38 ;
DR   Q830K4, THIM_ENTFA ;  A7MHJ8, THIM_ENTS8 ;  Q6D299, THIM_ERWCT ;
DR   B7LV66, THIM_ESCF3 ;  B1YJJ2, THIM_EXIS2 ;  C4KZE2, THIM_EXISA ;
DR   B0S0L6, THIM_FINM2 ;  C1AE25, THIM_GEMAT ;  Q5KZU2, THIM_GEOKA ;
DR   C5D2N0, THIM_GEOSW ;  A4IN26, THIM_GEOTN ;  Q0BVF4, THIM_GRABC ;
DR   Q4QNC8, THIM_HAEI8 ;  A5UA73, THIM_HAEIE ;  A5UGS9, THIM_HAEIG ;
DR   Q57233, THIM_HAEIN ;  B8F7P4, THIM_HAEPS ;  Q0I129, THIM_HAES1 ;
DR   Q18GX8, THIM_HALWD ;  B5Z7K9, THIM_HELPG ;  Q1CT25, THIM_HELPH ;
DR   Q9ZKZ9, THIM_HELPJ ;  B2USY3, THIM_HELPS ;  O25516, THIM_HELPY ;
DR   A9AZE0, THIM_HERA2 ;  A6W6A1, THIM_KINRD ;  B5XP99, THIM_KLEP3 ;
DR   A6TBJ8, THIM_KLEP7 ;  Q03NR9, THIM_LACBA ;  Q03CB3, THIM_LACC3 ;
DR   B3W782, THIM_LACCB ;  B2GBV7, THIM_LACF3 ;  Q9CG46, THIM_LACLA ;
DR   A2RKJ5, THIM_LACLM ;  Q02YS4, THIM_LACLS ;  Q890C2, THIM_LACPL ;
DR   A5VK99, THIM_LACRD ;  B2G7Q2, THIM_LACRJ ;  Q38ZL9, THIM_LACSS ;
DR   C1DCM4, THIM_LARHH ;  B0SE82, THIM_LEPBA ;  Q04V49, THIM_LEPBJ ;
DR   Q04YC8, THIM_LEPBL ;  B0SMR8, THIM_LEPBP ;  B1Y3E4, THIM_LEPCP ;
DR   Q72U64, THIM_LEPIC ;  Q8F0X6, THIM_LEPIN ;  B1MX61, THIM_LEUCK ;
DR   Q92EW7, THIM_LISIN ;  C1KZ32, THIM_LISMC ;  Q723Z1, THIM_LISMF ;
DR   B8DET2, THIM_LISMH ;  Q8YA46, THIM_LISMO ;  A0AFC3, THIM_LISW6 ;
DR   B1HX32, THIM_LYSSC ;  B9E8D6, THIM_MACCJ ;  Q8TMD5, THIM_METAC ;
DR   A7IA08, THIM_METB6 ;  Q466J4, THIM_METBF ;  Q2FNE1, THIM_METHJ ;
DR   A2SU11, THIM_METLZ ;  A4FX33, THIM_METM5 ;  A9AAH0, THIM_METM6 ;
DR   A6VG82, THIM_METM7 ;  Q8PS50, THIM_METMA ;  A3CS46, THIM_METMJ ;
DR   Q6LY53, THIM_METMP ;  B8GJF9, THIM_METPE ;  A5ULP3, THIM_METS3 ;
DR   A6UPE5, THIM_METVS ;  Q2RGX6, THIM_MOOTA ;  Q3IP35, THIM_NATPD ;
DR   B2A1A8, THIM_NATTJ ;  P57931, THIM_PASMU ;  C6DBE0, THIM_PECCP ;
DR   Q03GM6, THIM_PEDPA ;  Q6LPQ4, THIM_PHOPR ;  Q6A9C5, THIM_PROAC ;
DR   A1SX95, THIM_PSYIN ;  A5WDP1, THIM_PSYWF ;  Q9UZQ4, THIM_PYRAB ;
DR   Q8U191, THIM_PYRFU ;  O58877, THIM_PYRHO ;  B3Q1Q5, THIM_RHIE6 ;
DR   Q2K0X8, THIM_RHIEC ;  Q1M5U3, THIM_RHIL3 ;  B6A3G5, THIM_RHILW ;
DR   C1A163, THIM_RHOE4 ;  Q21VL4, THIM_RHOFD ;  A3PM38, THIM_RHOS1 ;
DR   Q3J061, THIM_RHOS4 ;  A4WQ25, THIM_RHOS5 ;  B9KL69, THIM_RHOSK ;
DR   A7NRF8, THIM_ROSCS ;  Q162K5, THIM_ROSDO ;  A5UUL2, THIM_ROSS1 ;
DR   Q1ASC4, THIM_RUBXD ;  B5EXY6, THIM_SALA4 ;  A9MKV9, THIM_SALAR ;
DR   Q57MJ3, THIM_SALCH ;  B5FMW2, THIM_SALDC ;  B5R0D9, THIM_SALEP ;
DR   B5RBY7, THIM_SALG2 ;  B4T9W1, THIM_SALHS ;  B4SXX8, THIM_SALNS ;
DR   Q5PMV9, THIM_SALPA ;  A9N7J2, THIM_SALPB ;  C0Q0Y8, THIM_SALPC ;
DR   B5BF36, THIM_SALPK ;  B4TNK3, THIM_SALSV ;  Q8Z5C8, THIM_SALTI ;
DR   P55883, THIM_SALTY ;  A8GHT4, THIM_SERP5 ;  B2TY84, THIM_SHIB3 ;
DR   Q323B8, THIM_SHIBS ;  Q32EA0, THIM_SHIDS ;  Q0T335, THIM_SHIF8 ;
DR   Q83KH2, THIM_SHIFL ;  Q3Z0A6, THIM_SHISS ;  A7X4S9, THIM_STAA1 ;
DR   A6U3H8, THIM_STAA2 ;  Q2FF34, THIM_STAA3 ;  Q2FWG2, THIM_STAA8 ;
DR   A5IUN8, THIM_STAA9 ;  Q2YUL1, THIM_STAAB ;  Q5HEA7, THIM_STAAC ;
DR   A6QIT6, THIM_STAAE ;  P66922, THIM_STAAM ;  P66923, THIM_STAAN ;
DR   Q6GEY3, THIM_STAAR ;  Q6G7L8, THIM_STAAS ;  Q8NVH4, THIM_STAAW ;
DR   Q9RGS6, THIM_STACT ;  Q5HMC9, THIM_STAEQ ;  Q8CRN9, THIM_STAES ;
DR   Q4L7X4, THIM_STAHJ ;  Q49Z40, THIM_STAS1 ;  Q3K1L7, THIM_STRA1 ;
DR   Q8E5X0, THIM_STRA3 ;  Q8E093, THIM_STRA5 ;  A4W0K2, THIM_STRS2 ;
DR   A4VUB1, THIM_STRSY ;  Q2LWX9, THIM_SYNAS ;  A0LP26, THIM_SYNFM ;
DR   Q0AZ87, THIM_SYNWW ;  B0KBA7, THIM_THEP3 ;  B0K3V0, THIM_THEPX ;
DR   Q8R807, THIM_THETN ;  C4L8H9, THIM_TOLAT ;  Q0W1L9, THIM_UNCMA ;
DR   Q5E0Q5, THIM_VIBF1 ;  B5ET96, THIM_VIBFM ;  A7N7S2, THIM_VIBHB ;
DR   Q87JW7, THIM_VIBPA ;  B7VS66, THIM_VIBSL ;  A1JQJ2, THIM_YERE8 ;
//
ID   2.7.1.51
DE   L-fuculokinase.
CA   ATP + L-fuculose = ADP + L-fuculose 1-phosphate.
PR   PROSITE; PDOC00408;
DR   Q8X6R3, FUCK_ECO57 ;  P11553, FUCK_ECOLI ;  P44399, FUCK_HAEIN ;
DR   Q8Z428, FUCK_SALTI ;  Q8ZMC5, FUCK_SALTY ;
//
ID   2.7.1.52
DE   Fucokinase.
AN   ATP:6-deoxy-L-galactose 1-phosphotransferase.
AN   Fucokinase (phosphorylating).
AN   Fucose kinase.
AN   L-fucokinase.
AN   L-fucose kinase.
CA   ATP + L-fucose = ADP + beta-L-fucose 1-phosphate.
CF   Divalent cation.
CC   -!- Forms part of a salvage pathway for reutilization of L-fucose.
CC   -!- Can also phosphorylate D-arabinose, but more slowly.
DR   Q9LNJ9, FKGP_ARATH ;  Q8N0W3, FUK_HUMAN  ;
//
ID   2.7.1.53
DE   L-xylulokinase.
AN   L-xylulose kinase.
CA   ATP + L-xylulose = ADP + L-xylulose 5-phosphate.
PR   PROSITE; PDOC00408;
DR   P37677, LYXK_ECOLI ;  P44991, LYXK_HAEIN ;  P57928, LYXK_PASMU ;
//
ID   2.7.1.54
DE   D-arabinokinase.
CA   ATP + D-arabinose = ADP + D-arabinose 5-phosphate.
//
ID   2.7.1.55
DE   Allose kinase.
AN   Allokinase.
CA   ATP + D-allose = ADP + D-allose 6-phosphate.
DR   P32718, ALSK_ECOLI ;
//
ID   2.7.1.56
DE   1-phosphofructokinase.
AN   Fructose 1-phosphate kinase.
CA   ATP + D-fructose 1-phosphate = ADP + D-fructose 1,6-bisphosphate.
CC   -!- ITP, GTP or UTP can replace ATP.
PR   PROSITE; PDOC00504;
DR   Q49396, FRUK_MYCGE ;  P75038, FRUK_MYCPN ;  O31714, K1PF_BACSU ;
DR   O51575, K1PF_BORBU ;  P0AEX1, K1PF_ECO57 ;  P0AEX0, K1PF_ECOL6 ;
DR   P0AEW9, K1PF_ECOLI ;  P44330, K1PF_HAEIN ;  P23386, K1PF_RHOCA ;
DR   P0AEX2, K1PF_SHIFL ;  P23354, K1PF_XANCP ;
//
ID   2.7.1.57
DE   Deleted entry.
//
ID   2.7.1.58
DE   2-dehydro-3-deoxygalactonokinase.
AN   2-keto-3-deoxy-galactonokinase.
AN   2-oxo-3-deoxygalactonate kinase.
CA   ATP + 2-dehydro-3-deoxy-D-galactonate = ADP + 2-dehydro-3-deoxy-D-
CA   galactonate 6-phosphate.
DR   P31459, DGOK_ECOLI ;
//
ID   2.7.1.59
DE   N-acetylglucosamine kinase.
AN   GlcNAc kinase.
CA   ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate.
CC   -!- The bacterial enzyme also acts on D-glucose.
DR   B6EKQ4, NAGK_ALISL ;  Q3SZM9, NAGK_BOVIN ;  A8AHU6, NAGK_CITK8 ;
DR   Q54PM7, NAGK_DICDI ;  A7ZKM3, NAGK_ECO24 ;  B7UPY3, NAGK_ECO27 ;
DR   B7MJA6, NAGK_ECO45 ;  B7LG53, NAGK_ECO55 ;  Q8X8E1, NAGK_ECO57 ;
DR   B5YWJ2, NAGK_ECO5E ;  B7NKG0, NAGK_ECO7I ;  B7MTP9, NAGK_ECO81 ;
DR   B7LX53, NAGK_ECO8A ;  C4ZS59, NAGK_ECOBW ;  B1XA29, NAGK_ECODH ;
DR   A7ZZ76, NAGK_ECOHS ;  A1AA13, NAGK_ECOK1 ;  Q0TIV5, NAGK_ECOL5 ;
DR   Q8FIM5, NAGK_ECOL6 ;  B1IUE6, NAGK_ECOLC ;  P75959, NAGK_ECOLI ;
DR   B7NAZ7, NAGK_ECOLU ;  B6I9J7, NAGK_ECOSE ;  B1LI25, NAGK_ECOSM ;
DR   Q1RD35, NAGK_ECOUT ;  Q6D662, NAGK_ERWCT ;  B2VDQ9, NAGK_ERWT9 ;
DR   B7LPQ4, NAGK_ESCF3 ;  Q4QP08, NAGK_HAEI8 ;  P44554, NAGK_HAEIN ;
DR   Q0I4A5, NAGK_HAES1 ;  Q9UJ70, NAGK_HUMAN ;  Q65SC6, NAGK_MANSM ;
DR   P86200, NAGK_MESAU ;  Q9QZ08, NAGK_MOUSE ;  Q9CMX5, NAGK_PASMU ;
DR   C6DKQ4, NAGK_PECCP ;  Q6LRC2, NAGK_PHOPR ;  P81799, NAGK_RAT   ;
DR   B5F8D3, NAGK_SALA4 ;  A9MG95, NAGK_SALAR ;  Q57QD5, NAGK_SALCH ;
DR   B5FK86, NAGK_SALDC ;  B5QXB6, NAGK_SALEP ;  B5RB82, NAGK_SALG2 ;
DR   B4TFJ6, NAGK_SALHS ;  B4T3Q8, NAGK_SALNS ;  Q5PGR8, NAGK_SALPA ;
DR   A9N4M6, NAGK_SALPB ;  C0Q772, NAGK_SALPC ;  B5BAF5, NAGK_SALPK ;
DR   B4TTJ1, NAGK_SALSV ;  Q8Z7H9, NAGK_SALTI ;  Q8ZPZ9, NAGK_SALTY ;
DR   Q31ZH6, NAGK_SHIBS ;  Q32EX9, NAGK_SHIDS ;  Q0T5R7, NAGK_SHIF8 ;
DR   Q83RR9, NAGK_SHIFL ;  Q3Z2Z8, NAGK_SHISS ;  Q9KRV2, NAGK_VIBCH ;
DR   Q5E4Z3, NAGK_VIBF1 ;  B5FEF2, NAGK_VIBFM ;  Q87PK8, NAGK_VIBPA ;
DR   B7VNU4, NAGK_VIBSL ;  Q8D9M7, NAGK_VIBVU ;  Q7MKQ9, NAGK_VIBVY ;
DR   A1JL75, NAGK_YERE8 ;  A7FH52, NAGK_YERP3 ;  Q1C6R0, NAGK_YERPA ;
DR   B2K721, NAGK_YERPB ;  Q0WGE8, NAGK_YERPE ;  Q1CI48, NAGK_YERPN ;
DR   Q669P5, NAGK_YERPS ;  B1JI57, NAGK_YERPY ;
//
ID   2.7.1.60
DE   N-acylmannosamine kinase.
CA   ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate.
CC   -!- Acts on the acetyl and glycolyl derivatives.
DR   Q7TQ49, GLCNE_CRIGR;  Q9Y223, GLCNE_HUMAN;  Q91WG8, GLCNE_MOUSE;
DR   O35826, GLCNE_RAT  ;  Q8YBP2, NANEK_BRUME;  Q8FWN5, NANEK_BRUSU;
DR   Q8FD60, NANK1_ECOL6;  Q8FDU8, NANK2_ECOL6;  A8AQB2, NANK_CITK8 ;
DR   A7ZSB5, NANK_ECO24 ;  B7UJV5, NANK_ECO27 ;  B7MBY4, NANK_ECO45 ;
DR   B7LHT0, NANK_ECO55 ;  Q8X9H0, NANK_ECO57 ;  B5YSU9, NANK_ECO5E ;
DR   B7NKT3, NANK_ECO7I ;  C4ZSW0, NANK_ECOBW ;  B1XHJ5, NANK_ECODH ;
DR   A8A532, NANK_ECOHS ;  A1AGB6, NANK_ECOK1 ;  Q0TCP4, NANK_ECOL5 ;
DR   B1IQQ7, NANK_ECOLC ;  P45425, NANK_ECOLI ;  B6I1U0, NANK_ECOSE ;
DR   B1LGI7, NANK_ECOSM ;  B7LRJ0, NANK_ESCF3 ;  Q4QP43, NANK_HAEI8 ;
DR   A5UB07, NANK_HAEIE ;  A5UFU9, NANK_HAEIG ;  P44541, NANK_HAEIN ;
DR   Q9CKB3, NANK_PASMU ;  B5F7J6, NANK_SALA4 ;  A9MNY9, NANK_SALAR ;
DR   B5FIR5, NANK_SALDC ;  B5R0K9, NANK_SALEP ;  B5RET4, NANK_SALG2 ;
DR   B4TJR0, NANK_SALHS ;  B4T747, NANK_SALNS ;  Q5PLF2, NANK_SALPA ;
DR   A9N830, NANK_SALPB ;  B5BGP2, NANK_SALPK ;  B4TWI7, NANK_SALSV ;
DR   Q8Z3F1, NANK_SALTI ;  Q8ZLQ8, NANK_SALTY ;  B2U1W2, NANK_SHIB3 ;
DR   Q0T068, NANK_SHIF8 ;  P59437, NANK_SHIFL ;  A5F7C0, NANK_VIBC3 ;
DR   Q9KR61, NANK_VIBCH ;  C3LNA1, NANK_VIBCM ;  Q8D612, NANK_VIBVU ;
DR   Q7MD31, NANK_VIBVY ;  A7FG96, NANK_YERP3 ;  Q1C5U9, NANK_YERPA ;
DR   B2K945, NANK_YERPB ;  Q8ZCG9, NANK_YERPE ;  A9QZJ5, NANK_YERPG ;
DR   Q1CJY6, NANK_YERPN ;  A4TMJ3, NANK_YERPP ;  Q668J9, NANK_YERPS ;
DR   B1JFW2, NANK_YERPY ;
//
ID   2.7.1.61
DE   Acyl-phosphate--hexose phosphotransferase.
CA   Acyl phosphate + D-hexose = an acid + D-hexose phosphate.
CC   -!- Phosphorylates D-glucose and D-mannose on O-6, and D-fructose on O-1
CC       or O-6.
//
ID   2.7.1.62
DE   Phosphoramidate--hexose phosphotransferase.
CA   Phosphoramidate + D-hexose = NH(3) + alpha-D-hexose 1-phosphate.
CC   -!- Activity is observed with several hexoses; of these glucose is the
CC       best substrate and the product from it is alpha-D-glucose
CC       1-phosphate.
CC   -!- The phosphoramidate donor can be replaced by N-phosphoglycine and by
CC       an N-phosphohistidine.
CC   -!- May be identical with EC 3.1.3.9.
//
ID   2.7.1.63
DE   Polyphosphate--glucose phosphotransferase.
AN   Polyphosphate glucokinase.
CA   (Phosphate)(n) + D-glucose = (phosphate)(n-1) + D-glucose 6-phosphate.
CC   -!- Requires a neutral salt, e.g. KCl, for maximum activity.
CC   -!- Also acts on glucosamine.
DR   Q49988, PPGK_MYCLE ;  A5U654, PPGK_MYCTA ;  Q59568, PPGK_MYCTU ;
//
ID   2.7.1.64
DE   Inositol 3-kinase.
AN   Inositol 1-kinase.
AN   Myo-inositol 1-kinase.
AN   Myoinositol kinase.
CA   ATP + myo-inositol = ADP + 1D-myo-inositol 3-phosphate.
//
ID   2.7.1.65
DE   Scyllo-inosamine 4-kinase.
CA   ATP + 1-amino-1-deoxy-scyllo-inositol = ADP + 1-amino-1-deoxy-scyllo-
CA   inositol 4-phosphate.
CC   -!- Also acts on streptamine, 2-deoxystreptamine and 1D-1-guanidino-3-
CC       amino-1,3-dideoxy-scyllo-inositol.
//
ID   2.7.1.66
DE   Undecaprenol kinase.
AN   Isoprenoid-alcohol kinase.
CA   ATP + undecaprenol = ADP + undecaprenyl phosphate.
DR   P19638, UDPK_BACSU ;  Q05888, UDPK_STRMU ;
//
ID   2.7.1.67
DE   1-phosphatidylinositol 4-kinase.
AN   Phosphatidylinositol 4-kinase.
AN   Phosphatidylinositol kinase.
AN   Phosphatidylinositol kinase (phosphorylating).
AN   PI kinase.
AN   PI4-kinase.
AN   PI4K-alpha.
AN   PtdIns-4-kinase.
AN   Type II phosphatidylinositol kinase.
CA   ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-
CA   inositol 4-phosphate.
PR   PROSITE; PDOC00710;
DR   P42951, LSB6_YEAST ;  Q6PE18, P4K2A_DANRE;  Q9BTU6, P4K2A_HUMAN;
DR   Q2TBE6, P4K2A_MOUSE;  Q99M64, P4K2A_RAT  ;  Q08B31, P4K2A_XENLA;
DR   Q505I0, P4K2A_XENTR;  Q9C671, P4K2B_ARATH;  Q5ZIK0, P4K2B_CHICK;
DR   Q49GP5, P4K2B_DANRE;  Q8TCG2, P4K2B_HUMAN;  Q8CBQ5, P4K2B_MOUSE;
DR   Q5XIL2, P4K2B_RAT  ;  Q6DCQ8, P4K2B_XENLA;  Q28G26, P4K2B_XENTR;
DR   Q9SXA1, P4KA1_ARATH;  Q9C680, P4KA2_ARATH;  Q9FMJ0, P4KB1_ARATH;
DR   Q0WPX9, P4KB2_ARATH;  O02811, PI4KA_BOVIN;  P42356, PI4KA_HUMAN;
DR   O02810, PI4KB_BOVIN;  B0KWC1, PI4KB_CALJA;  B1MTG7, PI4KB_CALMO;
DR   Q49GP3, PI4KB_DANRE;  Q9UBF8, PI4KB_HUMAN;  Q8BKC8, PI4KB_MOUSE;
DR   B4UT09, PI4KB_OTOGA;  A9X1A0, PI4KB_PAPAN;  O08561, PI4KB_RAT  ;
DR   B2KI64, PI4KB_RHIFE;  B3EX61, PI4KB_SORAR;  Q6GN16, PI4KB_XENLA;
DR   A4IID4, PI4KB_XENTR;  P54677, PI4K_DICDI ;  Q9UW24, PIK1A_CANAL;
DR   Q9UW20, PIK1_CANAL ;  P39104, PIK1_YEAST ;  Q8SQY7, STT4_ENCCU ;
DR   Q9USR3, STT4_SCHPO ;  P37297, STT4_YEAST ;  P32600, TOR2_YEAST ;
//
ID   2.7.1.68
DE   1-phosphatidylinositol-4-phosphate 5-kinase.
AN   Diphosphoinositide kinase.
AN   Phosphatidylinositol 4-phosphate kinase.
AN   Phosphatidylinositol-4-phosphate 5-kinase.
AN   PIP kinase.
AN   PtdIns(4)P-5-kinase.
AN   Type I PIP kinase.
CA   ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-
CA   1D-myo-inositol 4,5-bisphosphate.
CC   -!- This enzyme can also phosphorylate PtdIns3P in the 4-position,
CC       and PtdIns, PtdIns3P and PtdIns(3,4)P(2) in the 5-position in vitro,
CC       but to a lesser extent.
CC   -!- The last of these reactions occurs in vivo and is physiologically
CC       relevant.
DR   O13853, ITS3_SCHPO ;  P38994, MSS4_YEAST ;  Q99755, PI51A_HUMAN;
DR   P70182, PI51A_MOUSE;  Q5ZJ58, PI51B_CHICK;  O14986, PI51B_HUMAN;
DR   P70181, PI51B_MOUSE;  Q5CZZ9, PI51B_RAT  ;  O60331, PI51C_HUMAN;
DR   O70161, PI51C_MOUSE;  Q5I6B8, PI51C_RAT  ;  Q56YP2, PI5K1_ARATH;
DR   Q6EX42, PI5K1_ORYSJ;  Q8L796, PI5K2_ARATH;  O48709, PI5K3_ARATH;
DR   Q9M1K2, PI5K4_ARATH;  Q9SLG9, PI5K5_ARATH;  Q9SFB8, PI5K6_ARATH;
DR   Q9SUI2, PI5K7_ARATH;  Q8RY89, PI5K8_ARATH;  Q8L850, PI5K9_ARATH;
DR   Q9LMN1, PI5KA_ARATH;  Q9M149, PI5KB_ARATH;  Q17QS4, PI5L1_BOVIN;
DR   Q5T9C9, PI5L1_HUMAN;  Q6U7H8, PI5L1_MOUSE;
//
ID   2.7.1.69
DE   Protein-N(pi)-phosphohistidine--sugar phosphotransferase.
AN   Enzyme II of the phosphotransferase system.
AN   PEP--sugar phosphotransferase enzyme II.
AN   PTS permease.
CA   Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB +
CA   sugar phosphate.
CC   -!- Comprises a group of related enzymes.
CC   -!- The protein substrate is a phosphocarrier protein of low molecular
CC       mass (9.5 kDa).
CC   -!- The protein is phosphorylated in a reaction catalyzed by EC 2.7.3.9
CC       and this acts as the phosphate donor for the above reaction.
CC   -!- The enzyme translocates the sugar it phosphorylates into bacteria.
CC   -!- Aldohexoses and their glycosides and alditols are phosphorylated on
CC       O-6; fructose and sorbose on O-1.
CC   -!- Glycerone and disaccharides are also substrates.
PR   PROSITE; PDOC00795;
DR   P54745, HRSA_ECOLI ;  P46321, LICR_BACSU ;  O31644, MANR_BACSU ;
DR   P96574, MTLR_BACSU ;  P55901, PTEB_AERHY ;  O05505, PTEB_BACSU ;
DR   Q45399, PTEB_GEOSE ;  P71012, PTF3A_BACSU;  P47308, PTF3A_MYCGE;
DR   P75039, PTF3A_MYCPN;  P23387, PTF3E_RHOCA;  P69810, PTFB1_ECO57;
DR   P69809, PTFB1_ECOL6;  P69808, PTFB1_ECOLI;  Q821A9, PTFB1_SHIFL;
DR   P69818, PTFB2_ECO57;  P69817, PTFB2_ECOL6;  P69816, PTFB2_ECOLI;
DR   P69819, PTFB2_SHIFL;  P32676, PTFB3_ECOLI;  P20966, PTFBC_ECOLI;
DR   P44714, PTFBC_HAEIN;  P23355, PTFBC_XANCP;  P26380, PTFB_BACSU ;
DR   P32154, PTFLB_ECOLI;  Q45298, PTG3B_CORGL;  P20166, PTG3C_BACSU;
DR   P42015, PTG3C_GEOSE;  P47315, PTG3C_MYCGE;  P75569, PTG3C_MYCPN;
DR   A7WXI2, PTG3C_STAA1;  A6TXX3, PTG3C_STAA2;  Q2FK73, PTG3C_STAA3;
DR   Q2G1G8, PTG3C_STAA8;  A5IP58, PTG3C_STAA9;  Q2YUZ1, PTG3C_STAAB;
DR   Q5HJI3, PTG3C_STAAC;  A6QDH3, PTG3C_STAAE;  Q99X32, PTG3C_STAAM;
DR   Q7A807, PTG3C_STAAN;  Q6GKB7, PTG3C_STAAR;  Q6GCT7, PTG3C_STAAS;
DR   A8Z0F5, PTG3C_STAAT;  Q8NYM1, PTG3C_STAAW;  Q57071, PTG3C_STACT;
DR   Q8VRH0, PTG3C_STAEP;  Q5HL73, PTG3C_STAEQ;  Q7CCJ4, PTG3C_STAES;
DR   Q4L945, PTG3C_STAHJ;  Q4A0C4, PTG3C_STAS1;  P35595, PTG3C_STRPN;
DR   P57437, PTGCB_BUCAI;  Q8K9J0, PTGCB_BUCAP;  Q89AG6, PTGCB_BUCBP;
DR   P69788, PTGCB_ECO57;  P69787, PTGCB_ECOL6;  P69786, PTGCB_ECOLI;
DR   P37439, PTGCB_SALTY;  O32333, PTHB_CLOB8 ;  P56580, PTHB_ECOLI ;
DR   O32522, PTHB_ERWAM ;  P24241, PTIBC_ECOLI;  P46318, PTJB_BACSU ;
DR   P0A436, PTKB_ECO57 ;  P0A435, PTKB_ECOL6 ;  P37188, PTKB_ECOLI ;
DR   P0A437, PTKB_SHIFL ;  P24400, PTLCB_LACCA;  P23531, PTLCB_LACLA;
DR   Q5HE15, PTLCB_STAAC;  Q931G6, PTLCB_STAAM;  Q99S77, PTLCB_STAAN;
DR   Q6GEN9, PTLCB_STAAR;  Q6G7C4, PTLCB_STAAS;  P11162, PTLCB_STAAU;
DR   Q7A092, PTLCB_STAAW;  Q5HM40, PTLCB_STAEQ;  Q8CNF7, PTLCB_STAES;
DR   Q4L869, PTLCB_STAHJ;  P50976, PTLCB_STRMU;  P57635, PTM3C_BUCAI;
DR   Q8K911, PTM3C_BUCAP;  Q89A36, PTM3C_BUCBP;  P00550, PTM3C_ECOLI;
DR   Q9XBM7, PTM3C_KLEPN;  Q9CLY8, PTM3C_PASMU;  Q9KKQ7, PTM3C_VIBCH;
DR   Q9K678, PTMCB_BACHD;  P42956, PTMCB_BACSU;  O65989, PTMCB_CLOAB;
DR   P69827, PTMCB_ECO57;  P69826, PTMCB_ECOLI;  P50852, PTMCB_GEOSE;
DR   P75146, PTMCB_MYCPN;  Q5HE48, PTMCB_STAAC;  Q99SA3, PTMCB_STAAM;
DR   Q7A4B3, PTMCB_STAAN;  Q6GES1, PTMCB_STAAR;  Q6G7F6, PTMCB_STAAS;
DR   Q7A0A4, PTMCB_STAAW;  P28008, PTMCB_STACA;  Q4L9Y1, PTMCB_STAHJ;
DR   Q49ZA3, PTMCB_STAS1;  Q9KJ75, PTMCB_STRMU;  Q97SH4, PTMCB_STRPN;
DR   Q8DR34, PTMCB_STRR6;  O31645, PTN3B_BACSU;  Q46072, PTN3B_CORGL;
DR   P69799, PTNAB_ECO57;  P69798, PTNAB_ECOL6;  P69797, PTNAB_ECOLI;
DR   P69800, PTNAB_SHIFL;  Q5XAF5, PTNAB_STRP6;  P54715, PTOCB_BACSU;
DR   P19642, PTOCB_ECOLI;  P42909, PTPB1_ECOLI;  P42904, PTPB2_ECOLI;
DR   P69830, PTQB_ECO57 ;  P69796, PTQB_ECOL6 ;  P69795, PTQB_ECOLI ;
DR   P37081, PTRB_KLEPN ;  P43470, PTS3B_PEDPE;  P12655, PTS3B_STRMU;
DR   P05306, PTSBC_BACSU;  P27219, PTSBC_KLEPN;  Q9CJZ2, PTSBC_PASMU;
DR   P08470, PTSBC_SALTY;  P51184, PTSBC_STAXY;  P22825, PTSBC_VIBAL;
DR   Q04938, PTSB_LACLA ;  P39794, PTTBC_BACSU;  P36672, PTTBC_ECOLI;
DR   A7X6P1, PTU3C_STAA1;  A6U4R9, PTU3C_STAA2;  Q2FDW8, PTU3C_STAA3;
DR   Q2FV87, PTU3C_STAA8;  A5IVW5, PTU3C_STAA9;  Q2YWC1, PTU3C_STAAB;
DR   Q5HD13, PTU3C_STAAC;  A6QK27, PTU3C_STAAE;  Q99R97, PTU3C_STAAM;
DR   Q7A3G4, PTU3C_STAAN;  Q6GDR0, PTU3C_STAAR;  Q6G6D6, PTU3C_STAAS;
DR   A8Z3D6, PTU3C_STAAT;  Q8NUS2, PTU3C_STAAW;  Q53922, PTU3C_STACT;
DR   O06900, PTUCB_FUSMR;  Q9AGA7, PTUCB_KLEPN;  Q9KF90, PTV3B_BACHD;
DR   P40739, PTV3B_BACSU;  P08722, PTV3B_ECOLI;  P26207, PTV3B_ERWCH;
DR   P39816, PTW3C_BACSU;  P09323, PTW3C_ECOLI;  P45604, PTW3C_KLEPN;
DR   O34521, PTWCB_BACSU;  Q797S1, PTXBC_BACSU;  Q2FK70, PTXBC_STAA3;
DR   Q2G1G5, PTXBC_STAA8;  Q2YV12, PTXBC_STAAB;  Q5HJI0, PTXBC_STAAC;
DR   Q99X29, PTXBC_STAAM;  Q7A804, PTXBC_STAAN;  Q6GKB4, PTXBC_STAAR;
DR   Q6GCT4, PTXBC_STAAS;  Q7A1Y1, PTXBC_STAAW;  Q5HLT2, PTXBC_STAEQ;
DR   Q8CNB2, PTXBC_STAES;  Q4L8H5, PTXBC_STAHJ;  Q49ZN7, PTXBC_STAS1;
DR   P69789, PTXB_ECOLI ;  P69790, PTXB_SHIFL ;  Q8XBJ1, PTYBC_ECO57;
DR   Q8FFA9, PTYBC_ECOL6;  P77272, PTYBC_ECOLI;  Q1R8U3, PTYBC_ECOUT;
DR   Q9CKN5, PTYBC_PASMU;  Q7N9D9, PTYBC_PHOLL;  Q31Y50, PTYBC_SHIBS;
DR   Q32DC5, PTYBC_SHIDS;  Q83QN3, PTYBC_SHIFL;  Q9KVD9, PTYBC_VIBCH;
DR   Q5E5T6, PTYBC_VIBF1;  Q87FD5, PTYBC_VIBPA;  Q8D4Z3, PTYBC_VIBVU;
DR   Q7MBS2, PTYBC_VIBVY;  P15400, SACX_BACSU ;  P58035, SGCB_ECOLI ;
DR   P69823, ULAB_ECO57 ;  Q8FAJ1, ULAB_ECOL6 ;  P69822, ULAB_ECOLI ;
DR   Q9EXD8, ULAB_MYCPN ;  Q57GJ8, ULAB_SALCH ;  Q5PJ47, ULAB_SALPA ;
DR   Q8Z171, ULAB_SALTI ;  Q8ZK89, ULAB_SALTY ;  Q31TC5, ULAB_SHIBS ;
DR   Q328K3, ULAB_SHIDS ;  Q83P29, ULAB_SHIFL ;  Q3YUF4, ULAB_SHISS ;
DR   Q49397, Y129_MYCGE ;  Q9PQW5, Y178_UREPA ;  P75507, Y268_MYCPN ;
DR   O51340, Y367_BORBU ;  Q5XCC7, Y801_STRP6 ;
//
ID   2.7.1.70
DE   Transferred entry: 2.7.11.1.
//
ID   2.7.1.71
DE   Shikimate kinase.
CA   ATP + shikimate = ADP + shikimate 3-phosphate.
PR   PROSITE; PDOC00868;
DR   A5H2Q8, ARO11_LODEL;  B6QWH9, ARO11_PENMQ;  A5H2P4, ARO12_LODEL;
DR   B6QCA7, ARO12_PENMQ;  C0NL63, ARO1_AJECG ;  C6HCG7, ARO1_AJECH ;
DR   A6R8Q8, ARO1_AJECN ;  C5G8R4, ARO1_AJEDR ;  C5JKE6, ARO1_AJEDS ;
DR   C5FQ73, ARO1_ARTOC ;  Q74ZZ1, ARO1_ASHGO ;  A1CP85, ARO1_ASPCL ;
DR   B0XRM8, ARO1_ASPFC ;  B8N4Q9, ARO1_ASPFN ;  Q4WS76, ARO1_ASPFU ;
DR   Q2UCP6, ARO1_ASPOR ;  Q0D0F3, ARO1_ASPTN ;  Q5AME2, ARO1_CANAL ;
DR   B9WFG1, ARO1_CANDC ;  Q6FIV4, ARO1_CANGA ;  C5M1X2, ARO1_CANTT ;
DR   C4Y9D5, ARO1_CLAL4 ;  C5PA86, ARO1_COCP7 ;  A8NMB4, ARO1_COPC7 ;
DR   P0CM23, ARO1_CRYNB ;  P0CM22, ARO1_CRYNJ ;  P07547, ARO1_EMENI ;
DR   Q6CJC4, ARO1_KLULA ;  B0D6H2, ARO1_LACBS ;  C5DN02, ARO1_LACTC ;
DR   A4RD09, ARO1_MAGO7 ;  A8QCB2, ARO1_MALGO ;  C7YZ74, ARO1_NECH7 ;
DR   A1D244, ARO1_NEOFI ;  Q8X071, ARO1_NEUCR ;  C1H8L1, ARO1_PARBA ;
DR   C1FYJ9, ARO1_PARBD ;  C0S433, ARO1_PARBP ;  B6HAA7, ARO1_PENCW ;
DR   Q0V3H0, ARO1_PHANO ;  C4R4R8, ARO1_PICPG ;  A3LSZ2, ARO1_PICST ;
DR   Q12659, ARO1_PNECA ;  B2B223, ARO1_PODAN ;  B6JVD0, ARO1_SCHJY ;
DR   Q9P7R0, ARO1_SCHPO ;  A7F7H0, ARO1_SCLS1 ;  Q5XNP0, ARO1_SCLSC ;
DR   D1ZA70, ARO1_SORMK ;  B8M0U4, ARO1_TALSN ;  Q8J294, ARO1_THACU ;
DR   C4JYG6, ARO1_UNCRE ;  Q4P8F6, ARO1_USTMA ;  C9SE96, ARO1_VERA1 ;
DR   Q6C1X5, ARO1_YARLI ;  B3LGE9, ARO1_YEAS1 ;  C7GIN5, ARO1_YEAS2 ;
DR   A6ZY89, ARO1_YEAS7 ;  C8Z543, ARO1_YEAS8 ;  P08566, ARO1_YEAST ;
DR   C5DVG6, ARO1_ZYGRC ;  Q3A3N8, AROK1_PELCD;  Q3A2J4, AROK2_PELCD;
DR   Q8G5X4, AROKB_BIFLO;  Q9WYI3, AROKB_THEMA;  A1TKW2, AROK_ACIAC ;
DR   Q6F7E4, AROK_ACIAD ;  B0VQ33, AROK_ACIBS ;  B0V8M8, AROK_ACIBY ;
DR   A0LUH0, AROK_ACIC1 ;  A3MYR6, AROK_ACTP2 ;  B0BSJ7, AROK_ACTPJ ;
DR   A6VKZ6, AROK_ACTSZ ;  A0KN29, AROK_AERHH ;  Q9YEK6, AROK_AERPE ;
DR   A4SK24, AROK_AERS4 ;  B6EM43, AROK_ALISL ;  A8MFK5, AROK_ALKOO ;
DR   B4S0F6, AROK_ALTMD ;  B9MKD6, AROK_ANATD ;  Q3MFQ9, AROK_ANAVT ;
DR   O67925, AROK_AQUAE ;  Q9SJ05, AROK_ARATH ;  O29730, AROK_ARCFU ;
DR   Q5P5P2, AROK_AROAE ;  B6YQJ0, AROK_AZOPC ;  C3P8E3, AROK_BACAA ;
DR   C3LKR2, AROK_BACAC ;  B7JMV9, AROK_BACC0 ;  B7IXM2, AROK_BACC2 ;
DR   C1ERV8, AROK_BACC3 ;  B7HPD4, AROK_BACC7 ;  A7GSP5, AROK_BACCN ;
DR   B9IXM6, AROK_BACCQ ;  Q5LIQ7, AROK_BACFN ;  Q64ZU2, AROK_BACFR ;
DR   Q9KFH9, AROK_BACHD ;  Q65NN5, AROK_BACLD ;  A8F9S1, AROK_BACP2 ;
DR   P37944, AROK_BACSU ;  Q8A2B2, AROK_BACTN ;  A6L011, AROK_BACV8 ;
DR   A9VH19, AROK_BACWK ;  Q6G1N9, AROK_BARHE ;  Q6G1H5, AROK_BARQU ;
DR   Q1LU61, AROK_BAUCH ;  Q7VRN2, AROK_BLOFL ;  Q492A4, AROK_BLOPB ;
DR   Q2L1Z2, AROK_BORA1 ;  Q7WR85, AROK_BORBR ;  Q7W2B7, AROK_BORPA ;
DR   Q7VT94, AROK_BORPE ;  Q89XW7, AROK_BRAJA ;  B2S8S9, AROK_BRUA1 ;
DR   Q2YR42, AROK_BRUA2 ;  Q57AM8, AROK_BRUAB ;  A9M9B4, AROK_BRUC2 ;
DR   C0RFS0, AROK_BRUMB ;  B0CJD1, AROK_BRUSI ;  Q8FY59, AROK_BRUSU ;
DR   P57605, AROK_BUCAI ;  Q8K938, AROK_BUCAP ;  P59488, AROK_BUCBP ;
DR   Q62GA9, AROK_BURMA ;  Q3JMW0, AROK_BURP1 ;  Q63Q56, AROK_BURPS ;
DR   Q39KC5, AROK_BURS3 ;  Q2SU71, AROK_BURTA ;  A4XLN3, AROK_CALS8 ;
DR   B8H331, AROK_CAUCN ;  Q9A435, AROK_CAUCR ;  Q3AR93, AROK_CHLCH ;
DR   B3EIT1, AROK_CHLL2 ;  Q9PK27, AROK_CHLMU ;  B3QMM3, AROK_CHLP8 ;
DR   B3EPX3, AROK_CHLPB ;  A1BER1, AROK_CHLPD ;  Q9Z6M1, AROK_CHLPN ;
DR   B3QSZ9, AROK_CHLT3 ;  Q8KCL0, AROK_CHLTE ;  O84372, AROK_CHLTR ;
DR   Q1QZY3, AROK_CHRSD ;  Q7NZU3, AROK_CHRVO ;  A8AQU4, AROK_CITK8 ;
DR   A7FUV4, AROK_CLOB1 ;  C3KXE0, AROK_CLOB6 ;  A6M250, AROK_CLOB8 ;
DR   B2UYK3, AROK_CLOBA ;  B2TQ47, AROK_CLOBB ;  A5I323, AROK_CLOBH ;
DR   C1FPC6, AROK_CLOBJ ;  B1IMQ2, AROK_CLOBK ;  A7GEL1, AROK_CLOBL ;
DR   B1KT67, AROK_CLOBM ;  Q489N4, AROK_COLP3 ;  Q6NH03, AROK_CORDI ;
DR   Q8FT30, AROK_COREF ;  Q9X5D1, AROK_CORGL ;  Q4JVG1, AROK_CORJK ;
DR   B6J4A3, AROK_COXB1 ;  B6J3I0, AROK_COXB2 ;  A9KBB0, AROK_COXBN ;
DR   A9NB80, AROK_COXBR ;  Q83AJ3, AROK_COXBU ;  Q46WJ3, AROK_CUPPJ ;
DR   B7JZT6, AROK_CYAP8 ;  Q47JK7, AROK_DECAR ;  Q3Z991, AROK_DEHE1 ;
DR   A5FRZ4, AROK_DEHSB ;  Q3ZZK9, AROK_DEHSC ;  Q9RW93, AROK_DEIRA ;
DR   B1I3D6, AROK_DESAP ;  Q30XS2, AROK_DESDG ;  Q72DN7, AROK_DESVH ;
DR   B8E0Z4, AROK_DICTD ;  A7ZSR5, AROK_ECO24 ;  B7MD01, AROK_ECO45 ;
DR   P0A6D9, AROK_ECO57 ;  B7NMF3, AROK_ECO7I ;  B7M1U2, AROK_ECO8A ;
DR   B1X737, AROK_ECODH ;  A8A5J7, AROK_ECOHS ;  P0A6D8, AROK_ECOL6 ;
DR   B1IP75, AROK_ECOLC ;  P0A6D7, AROK_ECOLI ;  B7NDZ4, AROK_ECOLU ;
DR   A4WFH8, AROK_ENT38 ;  Q834S1, AROK_ENTFA ;  Q6CZQ8, AROK_ERWCT ;
DR   B2VJW8, AROK_ERWT9 ;  B7LS91, AROK_ESCF3 ;  A5FNY2, AROK_FLAJ1 ;
DR   A6GZJ6, AROK_FLAPJ ;  B0TXQ6, AROK_FRAP2 ;  Q2J827, AROK_FRASC ;
DR   Q14H72, AROK_FRAT1 ;  A7NBG9, AROK_FRATF ;  Q2A419, AROK_FRATH ;
DR   B2SGC8, AROK_FRATM ;  A0Q707, AROK_FRATN ;  Q0BMF5, AROK_FRATO ;
DR   Q5NFS0, AROK_FRATT ;  A4IYJ0, AROK_FRATW ;  Q8RF94, AROK_FUSNN ;
DR   Q5KY95, AROK_GEOKA ;  Q39X05, AROK_GEOMG ;  Q74BL5, AROK_GEOSL ;
DR   A4IPN9, AROK_GEOTN ;  Q7NH27, AROK_GLOVI ;  Q7VNR4, AROK_HAEDU ;
DR   Q4QNY3, AROK_HAEI8 ;  A5UAU9, AROK_HAEIE ;  A5UG09, AROK_HAEIG ;
DR   P43880, AROK_HAEIN ;  B0UTE7, AROK_HAES2 ;  Q2S9Q5, AROK_HAHCH ;
DR   A1WZB0, AROK_HALHL ;  B0R569, AROK_HALS3 ;  Q9HQB0, AROK_HALSA ;
DR   C4K6R0, AROK_HAMD5 ;  Q17YU7, AROK_HELAH ;  Q7VIH7, AROK_HELHP ;
DR   B6JPQ5, AROK_HELP2 ;  B5Z9T2, AROK_HELPG ;  Q1CV00, AROK_HELPH ;
DR   Q9ZMS3, AROK_HELPJ ;  B2URY7, AROK_HELPS ;  P56073, AROK_HELPY ;
DR   Q5QV48, AROK_IDILO ;  B2GCQ8, AROK_LACF3 ;  Q9CEU1, AROK_LACLA ;
DR   P43906, AROK_LACLM ;  Q02XD2, AROK_LACLS ;  Q5X6H1, AROK_LEGPA ;
DR   A5IFY0, AROK_LEGPC ;  Q5ZX01, AROK_LEGPH ;  Q5WXX6, AROK_LEGPL ;
DR   B0SI62, AROK_LEPBA ;  Q04NM2, AROK_LEPBJ ;  Q04WV5, AROK_LEPBL ;
DR   B0STS6, AROK_LEPBP ;  B9E6S1, AROK_MACCJ ;  Q2W095, AROK_MAGSA ;
DR   Q65R34, AROK_MANSM ;  A6W2T4, AROK_MARMS ;  Q8TR06, AROK_METAC ;
DR   Q12XK2, AROK_METBU ;  Q60BY3, AROK_METCA ;  B3DXL1, AROK_METI4 ;
DR   Q58835, AROK_METJA ;  A4FZL8, AROK_METM5 ;  A9A6N4, AROK_METM6 ;
DR   A6VIV9, AROK_METM7 ;  Q8PUH2, AROK_METMA ;  Q6M0F1, AROK_METMP ;
DR   A5ULG2, AROK_METS3 ;  O26896, AROK_METTH ;  A0B8V5, AROK_METTP ;
DR   A6URV6, AROK_METVS ;  B0JFW8, AROK_MICAN ;  Q2RI74, AROK_MOOTA ;
DR   A0QI60, AROK_MYCA1 ;  P0A4Z3, AROK_MYCBO ;  A1KLN6, AROK_MYCBP ;
DR   Q9CCS5, AROK_MYCLE ;  B2HNC7, AROK_MYCMM ;  Q741J8, AROK_MYCPA ;
DR   A5U5N8, AROK_MYCTA ;  P0A4Z2, AROK_MYCTU ;  A0PPH1, AROK_MYCUA ;
DR   Q5FAD3, AROK_NEIG1 ;  O50467, AROK_NEIGO ;  A9M1U5, AROK_NEIM0 ;
DR   P63599, AROK_NEIMA ;  P63600, AROK_NEIMB ;  Q82TC0, AROK_NITEU ;
DR   Q2YBB2, AROK_NITMU ;  Q3JEG4, AROK_NITOC ;  Q3SVM9, AROK_NITWN ;
DR   B2IX35, AROK_NOSP7 ;  Q8YXG9, AROK_NOSS1 ;  Q2G733, AROK_NOVAD ;
DR   Q8ENM6, AROK_OCEIH ;  A6LFQ8, AROK_PARD8 ;  P57925, AROK_PASMU ;
DR   Q3B316, AROK_PELLD ;  A5D373, AROK_PELTS ;  C0QR76, AROK_PERMH ;
DR   Q7NA55, AROK_PHOLL ;  Q6LVF6, AROK_PHOPR ;  B4S8Z9, AROK_PROA2 ;
DR   A2C650, AROK_PROM3 ;  A9BCW6, AROK_PROM4 ;  Q7VE85, AROK_PROMA ;
DR   Q7V904, AROK_PROMM ;  Q46HR4, AROK_PROMT ;  A4SFH8, AROK_PROVI ;
DR   Q48PH1, AROK_PSE14 ;  Q15Y43, AROK_PSEA6 ;  A6VDG0, AROK_PSEA7 ;
DR   B7V3D2, AROK_PSEA8 ;  Q02EX8, AROK_PSEAB ;  P34003, AROK_PSEAE ;
DR   Q1IGA8, AROK_PSEE4 ;  Q4KJI9, AROK_PSEF5 ;  Q3IJC5, AROK_PSEHT ;
DR   A5WAB2, AROK_PSEP1 ;  Q3KJA2, AROK_PSEPF ;  Q88CV1, AROK_PSEPK ;
DR   Q87V14, AROK_PSESM ;  Q4ZZE4, AROK_PSEU2 ;  Q4FQI2, AROK_PSYA2 ;
DR   Q1Q8Q8, AROK_PSYCK ;  A1SRB6, AROK_PSYIN ;  A5WCG4, AROK_PSYWF ;
DR   Q9V1H6, AROK_PYRAB ;  Q8U0A5, AROK_PYRFU ;  Q5JFT2, AROK_PYRKO ;
DR   Q8XV61, AROK_RALSO ;  Q98FY0, AROK_RHILO ;  B5ZSI5, AROK_RHILW ;
DR   Q92ME6, AROK_RHIME ;  Q7UU71, AROK_RHOBA ;  C0ZZB5, AROK_RHOE4 ;
DR   Q6NCG8, AROK_RHOPA ;  Q2RMW1, AROK_RHORT ;  Q3J2I9, AROK_RHOS4 ;
DR   Q0S0N1, AROK_RHOSR ;  A4FBE7, AROK_SACEN ;  B5F8K1, AROK_SALA4 ;
DR   A8LY07, AROK_SALAI ;  Q57IY7, AROK_SALCH ;  B5FJR0, AROK_SALDC ;
DR   B5R2D6, AROK_SALEP ;  B5R7M7, AROK_SALG2 ;  B4TKR3, AROK_SALHS ;
DR   B4SVI9, AROK_SALNS ;  Q5PLX1, AROK_SALPA ;  B5BH30, AROK_SALPK ;
DR   Q2S4T0, AROK_SALRD ;  B4TY47, AROK_SALSV ;  P63602, AROK_SALTI ;
DR   A4X608, AROK_SALTO ;  P63601, AROK_SALTY ;  A8GKQ8, AROK_SERP5 ;
DR   A1SB14, AROK_SHEAM ;  A3DA15, AROK_SHEB5 ;  A6WTR2, AROK_SHEB8 ;
DR   A9L695, AROK_SHEB9 ;  Q12SL9, AROK_SHEDO ;  Q088S7, AROK_SHEFN ;
DR   B0TL77, AROK_SHEHH ;  A3Q9D7, AROK_SHELP ;  Q8EK20, AROK_SHEON ;
DR   A8GZ29, AROK_SHEPA ;  A4YBT1, AROK_SHEPC ;  A0L243, AROK_SHESA ;
DR   A8G196, AROK_SHESH ;  Q0HDV6, AROK_SHESM ;  Q0I053, AROK_SHESR ;
DR   A1RPQ7, AROK_SHESW ;  B1KP71, AROK_SHEWM ;  B2U3J6, AROK_SHIB3 ;
DR   Q31VP4, AROK_SHIBS ;  Q32AK2, AROK_SHIDS ;  P0A6E0, AROK_SHIFL ;
DR   Q3YWN3, AROK_SHISS ;  Q5LSY0, AROK_SILPO ;  Q2NQJ1, AROK_SODGM ;
DR   Q00497, AROK_SOLLC ;  A7X2S4, AROK_STAA1 ;  A6U209, AROK_STAA2 ;
DR   Q2FY32, AROK_STAA8 ;  A5IT66, AROK_STAA9 ;  Q5HFM1, AROK_STAAC ;
DR   A6QH82, AROK_STAAE ;  P63605, AROK_STAAM ;  P63606, AROK_STAAN ;
DR   Q6GGG1, AROK_STAAR ;  Q6G928, AROK_STAAS ;  A8Z477, AROK_STAAT ;
DR   Q8NWC8, AROK_STAAW ;  Q5HP11, AROK_STAEQ ;  Q8CSF2, AROK_STAES ;
DR   Q4L6N8, AROK_STAHJ ;  Q49XY2, AROK_STAS1 ;  Q827R9, AROK_STRAW ;
DR   Q9KXQ5, AROK_STRCO ;  B4U247, AROK_STREM ;  A8AXY8, AROK_STRGC ;
DR   B4SSA3, AROK_STRM5 ;  B2FQI7, AROK_STRMK ;  Q1JB44, AROK_STRPB ;
DR   Q1JL88, AROK_STRPC ;  Q1JGC2, AROK_STRPD ;  Q1J634, AROK_STRPF ;
DR   A2RE14, AROK_STRPG ;  B5XM06, AROK_STRPZ ;  A4W070, AROK_STRS2 ;
DR   A4VTX6, AROK_STRSY ;  Q03LG8, AROK_STRTD ;  B2V895, AROK_SULSY ;
DR   Q67N09, AROK_SYMTH ;  Q2LUD6, AROK_SYNAS ;  Q31PU5, AROK_SYNE7 ;
DR   Q2JRJ6, AROK_SYNJA ;  Q2JKT7, AROK_SYNJB ;  Q5N4D3, AROK_SYNP6 ;
DR   Q7U469, AROK_SYNPX ;  A5GQN5, AROK_SYNR3 ;  Q3B009, AROK_SYNS9 ;
DR   Q3AH55, AROK_SYNSC ;  P72796, AROK_SYNY3 ;  Q9HLE5, AROK_THEAC ;
DR   Q8DKH7, AROK_THEEB ;  Q47QY8, AROK_THEFY ;  C5A784, AROK_THEGJ ;
DR   B0K9C2, AROK_THEP3 ;  B0K0S9, AROK_THEPX ;  Q72IW2, AROK_THET2 ;
DR   Q5SII4, AROK_THET8 ;  Q8RAE8, AROK_THETN ;  B5YHI3, AROK_THEYD ;
DR   Q31DP8, AROK_THICR ;  Q3SM89, AROK_THIDA ;  B8GPV2, AROK_THISH ;
DR   C4LB08, AROK_TOLAT ;  Q0W4U0, AROK_UNCMA ;  A5F523, AROK_VIBC3 ;
DR   Q9KNV1, AROK_VIBCH ;  Q5E2F9, AROK_VIBF1 ;  B5FBN2, AROK_VIBFM ;
DR   A7MSY3, AROK_VIBHB ;  Q87L67, AROK_VIBPA ;  Q8DCM1, AROK_VIBVU ;
DR   Q7MH83, AROK_VIBVY ;  Q8D1X8, AROK_WIGBR ;  Q8PI88, AROK_XANAC ;
DR   Q3BQS2, AROK_XANC5 ;  Q4UX85, AROK_XANC8 ;  Q8P6X4, AROK_XANCP ;
DR   Q2P6C8, AROK_XANOM ;  B2SK35, AROK_XANOP ;  Q5H3H3, AROK_XANOR ;
DR   B2I9G1, AROK_XYLF2 ;  Q9PDP4, AROK_XYLFA ;  B0U6C8, AROK_XYLFM ;
DR   Q87DU8, AROK_XYLFT ;  A1JSD4, AROK_YERE8 ;  A7FNT6, AROK_YERP3 ;
DR   Q1C2P2, AROK_YERPA ;  B2K5T5, AROK_YERPB ;  Q8ZJF7, AROK_YERPE ;
DR   A9R4B0, AROK_YERPG ;  Q1CCN9, AROK_YERPN ;  A4TGU1, AROK_YERPP ;
DR   Q664L9, AROK_YERPS ;  B1JIQ3, AROK_YERPY ;  Q5NPY7, AROK_ZYMMO ;
DR   A7ZID7, AROL_ECO24 ;  B7UJL2, AROL_ECO27 ;  B7MD47, AROL_ECO45 ;
DR   B7L543, AROL_ECO55 ;  P0A6E3, AROL_ECO57 ;  B5Z2U0, AROL_ECO5E ;
DR   B7NJB4, AROL_ECO7I ;  B7MPE9, AROL_ECO81 ;  B7M333, AROL_ECO8A ;
DR   C4ZTE7, AROL_ECOBW ;  B1XEX7, AROL_ECODH ;  A7ZX38, AROL_ECOHS ;
DR   A1A860, AROL_ECOK1 ;  Q0TKQ3, AROL_ECOL5 ;  P0A6E2, AROL_ECOL6 ;
DR   B1J060, AROL_ECOLC ;  P0A6E1, AROL_ECOLI ;  B7N8U0, AROL_ECOLU ;
DR   B6HZI8, AROL_ECOSE ;  B1LIS2, AROL_ECOSM ;  Q1RFF6, AROL_ECOUT ;
DR   A4W763, AROL_ENT38 ;  A7MLV5, AROL_ENTS8 ;  P10880, AROL_ERWCH ;
DR   Q6D872, AROL_ERWCT ;  B2VIT0, AROL_ERWT9 ;  B7LMJ7, AROL_ESCF3 ;
DR   C6DB04, AROL_PECCP ;  Q7N7B0, AROL_PHOLL ;  B5EWS0, AROL_SALA4 ;
DR   Q57SH6, AROL_SALCH ;  B5FKP3, AROL_SALDC ;  B5QTD7, AROL_SALEP ;
DR   B5R5X9, AROL_SALG2 ;  B4T8M7, AROL_SALHS ;  B4SW28, AROL_SALNS ;
DR   Q5PFV5, AROL_SALPA ;  A9MX50, AROL_SALPB ;  C0Q7R1, AROL_SALPC ;
DR   B5BDE5, AROL_SALPK ;  B4TZG1, AROL_SALSV ;  P63604, AROL_SALTI ;
DR   P63603, AROL_SALTY ;  A8GAI2, AROL_SERP5 ;  B2U3Z0, AROL_SHIB3 ;
DR   Q325L0, AROL_SHIBS ;  Q32JD7, AROL_SHIDS ;  Q0T7K0, AROL_SHIF8 ;
DR   Q83M66, AROL_SHIFL ;  Q3Z522, AROL_SHISS ;  Q2NVB6, AROL_SODGM ;
DR   A1JNV2, AROL_YERE8 ;  A7FLH5, AROL_YERP3 ;  Q1C4F3, AROL_YERPA ;
DR   B2K6Q9, AROL_YERPB ;  Q8ZC15, AROL_YERPE ;  A9R2W3, AROL_YERPG ;
DR   Q1CLC0, AROL_YERPN ;  A4TPJ4, AROL_YERPP ;  Q66DY2, AROL_YERPS ;
DR   B1JIG7, AROL_YERPY ;
//
ID   2.7.1.72
DE   Streptomycin 6-kinase.
AN   APH(6).
AN   Streptidine kinase.
AN   Streptomycin 6-phosphotransferase.
CA   ATP + streptomycin = ADP + streptomycin 6-phosphate.
CC   -!- dATP can replace ATP.
CC   -!- Dihydrostreptomycin, streptidine and 2-deoxystreptidine can act as
CC       acceptors.
DR   P18622, STRA_STRGA ;  P08077, STRA_STRGR ;
//
ID   2.7.1.73
DE   Inosine kinase.
AN   Inosine-guanosine kinase.
CA   ATP + inosine = ADP + IMP.
PR   PROSITE; PDOC00504;
DR   P0AEW8, INGK_ECO57 ;  P0AEW7, INGK_ECOL6 ;  P0AEW6, INGK_ECOLI ;
//
ID   2.7.1.74
DE   Deoxycytidine kinase.
CA   NTP + deoxycytidine = NDP + dCMP.
CC   -!- Cytosine arabinoside can act as acceptor; all natural nucleoside
CC       triphosphates (except dCTP) can act as donors.
DR   P21974, DCK1_FOWPN ;  Q9J579, DCK2_FOWPN ;  P37529, DCK_BACSU  ;
DR   Q3MHR2, DCK_BOVIN  ;  P27707, DCK_HUMAN  ;  P43346, DCK_MOUSE  ;
DR   P48769, DCK_RAT    ;
//
ID   2.7.1.75
DE   Transferred entry: 2.7.1.21.
//
ID   2.7.1.76
DE   Deoxyadenosine kinase.
CA   ATP + deoxyadenosine = ADP + dAMP.
CC   -!- Deoxyguanosine can also act as acceptor.
CC   -!- Possibly identical with EC 2.7.1.74.
DR   Q54YL2, DAK_DICDI  ;  P37529, DCK_BACSU  ;  P0C1F9, DGK1_LACAC ;
DR   Q74HC3, DGK1_LACJO ;
//
ID   2.7.1.77
DE   Nucleoside phosphotransferase.
CA   A nucleotide + a 2'-deoxynucleoside = a nucleoside + a 2'-deoxynucleoside
CA   5'-phosphate.
CC   -!- Phenyl phosphate and nucleoside 3'-phosphates can act as donors,
CC       although not so well as nucleoside 5'-phosphates.
CC   -!- Nucleosides as well as 2'-deoxynucleosides can act as acceptors.
//
ID   2.7.1.78
DE   Polynucleotide 5'-hydroxyl-kinase.
CA   ATP + 5'-dephospho-DNA = ADP + 5'-phospho-DNA.
CC   -!- Also acts on 5'-dephospho-RNA 3'-mononucleotides.
DR   A2VE01, CLP1_BOVIN ;  Q5ZJL4, CLP1_CHICK ;  Q92989, CLP1_HUMAN ;
DR   Q4R7R3, CLP1_MACFA ;  Q99LI9, CLP1_MOUSE ;  Q5PQL4, CLP1_RAT   ;
DR   Q6NS21, CLP1_XENLA ;  Q66JK4, CLP1_XENTR ;  P06855, KIPN_BPT4  ;
DR   O13911, PNK1_SCHPO ;  P41476, PNKL_NPVAC ;  Q96T60, PNKP_HUMAN ;
DR   Q5UQD2, PNKP_MIMIV ;  Q9JLV6, PNKP_MOUSE ;  Q58711, PRNK_METJA ;
DR   Q9V290, PRNK_PYRAB ;  Q8U4H6, PRNK_PYRFU ;  O57936, PRNK_PYRHO ;
DR   Q5JDN6, PRNK_PYRKO ;
//
ID   2.7.1.79
DE   Diphosphate--glycerol phosphotransferase.
AN   Pyrophosphate--glycerol phosphotransferase.
CA   Diphosphate + glycerol = phosphate + glycerol 1-phosphate.
CC   -!- May be identical with EC 3.1.3.9.
//
ID   2.7.1.80
DE   Diphosphate--serine phosphotransferase.
AN   Pyrophosphate--serine phosphotransferase.
CA   Diphosphate + L-serine = phosphate + O-phospho-L-serine.
//
ID   2.7.1.81
DE   Hydroxylysine kinase.
CA   GTP + 5-hydroxy-L-lysine = GDP + 5-phosphonooxy-L-lysine.
CC   -!- Both the natural 5-hydroxy-L-lysine and its 5-epimer act as
CC       acceptors.
//
ID   2.7.1.82
DE   Ethanolamine kinase.
CA   ATP + ethanolamine = ADP + O-phosphoethanolamine.
DR   P35790, CHKA_HUMAN ;  O54804, CHKA_MOUSE ;  Q01134, CHKA_RAT   ;
DR   Q9Y259, CHKB_HUMAN ;  O55229, CHKB_MOUSE ;  O54783, CHKB_RAT   ;
DR   P54352, EAS_DROME  ;  Q9HBU6, EKI1_HUMAN ;  Q9D4V0, EKI1_MOUSE ;
DR   Q03764, EKI1_YEAST ;  Q9NVF9, EKI2_HUMAN ;  A7MCT6, EKI2_MOUSE ;
DR   D3ZRW8, EKI2_RAT   ;  Q869T9, EKIA_DICDI ;  Q554D8, EKIB_DICDI ;
DR   A7SK27, EKI_NEMVE  ;
//
ID   2.7.1.83
DE   Pseudouridine kinase.
CA   ATP + pseudouridine = ADP + pseudouridine 5'-phosphate.
DR   P30235, PSUK_ECOLI ;  Q9USY1, YOW5_SCHPO ;
//
ID   2.7.1.84
DE   Alkylglycerone kinase.
CA   ATP + O-alkylglycerone = ADP + O-alkylglycerone phosphate.
//
ID   2.7.1.85
DE   Beta-glucoside kinase.
CA   ATP + cellobiose = ADP + 6-phospho-beta-D-glucosyl-(1->4)-D-glucose.
CC   -!- Phosphorylates a number of beta-D-glucosides.
CC   -!- GTP, CTP, ITP and UTP can also act as donors.
DR   Q93LQ8, BGLK_KLEPN ;  Q926Y3, BGLK_LISIN ;  Q8Y3R9, BGLK_LISMO ;
//
ID   2.7.1.86
DE   NADH kinase.
CA   ATP + NADH = ADP + NADPH.
CC   -!- CTP, ITP, UTP and GTP can also act as phosphate donors (in decreasing
CC       order of activity).
CC   -!- Specific for NADH.
CC   -!- Activated by acetate.
CC   -!- Formerly EC 2.7.1.96.
DR   Q500Y9, NADHK_ARATH;  Q6EQG2, NADHK_ORYSJ;  Q56YN3, NADK1_ARATH;
DR   Q06892, POS5_YEAST ;  P32622, YEF1_YEAST ;
//
ID   2.7.1.87
DE   Streptomycin 3''-kinase.
AN   Streptomycin 3''-phosphotransferase.
CA   ATP + streptomycin = ADP + streptomycin 3''-phosphate.
CC   -!- Also phosphorylates dihydrostreptomycin, 3'-deoxydihydrostreptomycin
CC       and their 6-phosphates.
DR   P18150, APHE_STRGR ;  P13082, STR_KLEPN  ;
//
ID   2.7.1.88
DE   Dihydrostreptomycin-6-phosphate 3'-alpha-kinase.
CA   ATP + dihydrostreptomycin 6-phosphate = ADP + dihydrostreptomycin
CA   3'-alpha,6-bisphosphate.
CC   -!- 3'-deoxydihydrostreptomycin 6-phosphate can also act as acceptor.
//
ID   2.7.1.89
DE   Thiamine kinase.
CA   ATP + thiamine = ADP + thiamine phosphate.
DR   A7ZKL0, THIK_ECO24 ;  B7UPC2, THIK_ECO27 ;  B7MJ93, THIK_ECO45 ;
DR   Q8X8G6, THIK_ECO57 ;  B5YVX5, THIK_ECO5E ;  B7MTN6, THIK_ECO81 ;
DR   C4ZS46, THIK_ECOBW ;  B1XA16, THIK_ECODH ;  A7ZZ64, THIK_ECOHS ;
DR   A1AA00, THIK_ECOK1 ;  Q0TIW8, THIK_ECOL5 ;  Q8FIN3, THIK_ECOL6 ;
DR   B1IUF9, THIK_ECOLC ;  P75948, THIK_ECOLI ;  B7NAY4, THIK_ECOLU ;
DR   B1LI38, THIK_ECOSM ;  Q1RD48, THIK_ECOUT ;  B5F8E6, THIK_SALA4 ;
DR   Q57QE7, THIK_SALCH ;  B5FK99, THIK_SALDC ;  B5QXC8, THIK_SALEP ;
DR   B5RB94, THIK_SALG2 ;  B4TFI3, THIK_SALHS ;  B4T340, THIK_SALNS ;
DR   Q5PGS9, THIK_SALPA ;  A9N5J7, THIK_SALPB ;  C0Q785, THIK_SALPC ;
DR   B5BAG8, THIK_SALPK ;  B4TTH8, THIK_SALSV ;  Q8Z7I7, THIK_SALTI ;
DR   Q8ZQ07, THIK_SALTY ;  Q31ZG3, THIK_SHIBS ;  Q32EW6, THIK_SHIDS ;
DR   Q0T5T0, THIK_SHIF8 ;  Q83LH9, THIK_SHIFL ;  Q3Z311, THIK_SHISS ;
//
ID   2.7.1.90
DE   Diphosphate--fructose-6-phosphate 1-phosphotransferase.
AN   6-phosphofructokinase (diphosphate).
AN   6-phosphofructokinase (pyrophosphate).
AN   Diphosphate-dependent 6-phosphofructose-1-kinase.
AN   Pyrophosphate--fructose 6-phosphate 1-phosphotransferase.
AN   Pyrophosphate-dependent 6-phosphofructose-1-kinase.
CA   Diphosphate + D-fructose 6-phosphate = phosphate + D-fructose 1,6-
CA   bisphosphate.
DR   Q41140, PFPA_RICCO ;  P21342, PFPA_SOLTU ;  Q41141, PFPB_RICCO ;
DR   P21343, PFPB_SOLTU ;  Q9AGC0, PFP_AMYMD  ;  Q59126, PFP_AMYME  ;
DR   Q9KH71, PFP_DICTH  ;  P29495, PFP_PROFR  ;
//
ID   2.7.1.91
DE   Sphinganine kinase.
AN   Dihydrosphingosine kinase.
CA   ATP + sphinganine = ADP + sphinganine 1-phosphate.
PR   PROSITE; PDOC50146;
DR   Q12246, LCB4_YEAST ;  Q06147, LCB5_YEAST ;  Q9NYA1, SPHK1_HUMAN;
DR   Q8CI15, SPHK1_MOUSE;  Q91V26, SPHK1_RAT  ;  Q9NRA0, SPHK2_HUMAN;
DR   Q9JIA7, SPHK2_MOUSE;  Q86KF9, SPHKA_DICDI;  Q6B516, SPHKB_DICDI;
//
ID   2.7.1.92
DE   5-dehydro-2-deoxygluconokinase.
AN   5-keto-2-deoxygluconokinase.
CA   ATP + 5-dehydro-2-deoxy-D-gluconate = ADP + 6-phospho-5-dehydro-2-deoxy-
CA   D-gluconate.
DR   Q63B75, IOLC1_BACCZ;  Q4V1F7, IOLC2_BACCZ;  A7ZAH9, IOLC_BACA2 ;
DR   C3PAZ0, IOLC_BACAA ;  C3LHY4, IOLC_BACAC ;  A0REB4, IOLC_BACAH ;
DR   Q81QB7, IOLC_BACAN ;  C1EVJ1, IOLC_BACC3 ;  Q9KAG8, IOLC_BACHD ;
DR   Q6HIK4, IOLC_BACHK ;  Q65D02, IOLC_BACLD ;  Q5WKY9, IOLC_BACSK ;
DR   P42414, IOLC_BACSU ;  A6M229, IOLC_CLOB8 ;  B2V4J8, IOLC_CLOBA ;
DR   B2TJ78, IOLC_CLOBB ;  Q0TUZ4, IOLC_CLOP1 ;  Q8XP78, IOLC_CLOPE ;
DR   Q898F0, IOLC_CLOTE ;  Q5KYR3, IOLC_GEOKA ;  A4IPB3, IOLC_GEOTN ;
DR   A5YBJ5, IOLC_LACCA ;  Q92EQ5, IOLC_LISIN ;  C1KZA1, IOLC_LISMC ;
DR   Q723S9, IOLC_LISMF ;  B8DCT6, IOLC_LISMH ;  Q8Y9Y2, IOLC_LISMO ;
DR   Q601P9, IOLC_MYCH2 ;  Q4A8D9, IOLC_MYCH7 ;  Q4AAB0, IOLC_MYCHJ ;
DR   Q6LK43, IOLC_PHOPR ;
//
ID   2.7.1.93
DE   Alkylglycerol kinase.
CA   ATP + 1-O-alkyl-sn-glycerol = ADP + 1-O-alkyl-sn-glycerol 3-phosphate.
//
ID   2.7.1.94
DE   Acylglycerol kinase.
AN   Monoacylglycerol kinase.
CA   ATP + acylglycerol = ADP + acyl-sn-glycerol 3-phosphate.
CC   -!- Acts on both 1- and 2-acylglycerols.
PR   PROSITE; PDOC50146;
DR   Q7ZW00, AGK_DANRE  ;  Q53H12, AGK_HUMAN  ;  Q9ESW4, AGK_MOUSE  ;
DR   Q5RED7, AGK_PONAB  ;  Q7ZYJ3, AGK_XENLA  ;
//
ID   2.7.1.95
DE   Kanamycin kinase.
AN   Aminoglycoside 3'-phosphotransferase.
AN   APH(3').
AN   Neomycin-kanamycin phosphotransferase.
CA   ATP + kanamycin = ADP + kanamycin 3'-phosphate.
CC   -!- Also acts on the antibiotics neomycin, paromomycin, neamine,
CC       paromamine, vistamycin and gentamicin A.
CC   -!- An enzyme from Pseudomonas aeruginosa also acts on butirosin.
DR   P00551, KKA1_ECOLX ;  Q03447, KKA1_SALTY ;  P00552, KKA2_KLEPN ;
DR   P0A3Y5, KKA3_ENTFA ;  P0A3Y6, KKA3_STAAU ;  P00553, KKA4_BACCI ;
DR   P00555, KKA5_STRFR ;  P09885, KKA6_ACIBA ;  P14508, KKA7_CAMJE ;
DR   P14509, KKA8_ECOLX ;  P13250, KKA9_STRRI ;  Q02149, KKIH_LACLA ;
//
ID   2.7.1.96
DE   Transferred entry: 2.7.1.86.
//
ID   2.7.1.97
DE   Transferred entry: 2.7.11.14.
//
ID   2.7.1.98
DE   Deleted entry.
//
ID   2.7.1.99
DE   Transferred entry: 2.7.11.2.
//
ID   2.7.1.100
DE   S-methyl-5-thioribose kinase.
AN   5-methylthioribose kinase.
AN   Methylthioribose kinase.
AN   MTR kinase.
CA   ATP + S-methyl-5-thio-D-ribose = ADP + S-methyl-5-thio-alpha-D-ribose
CA   1-phosphate.
CC   -!- Also acts, more slowly, on CTP.
DR   Q7XR61, MTK1_ORYSJ ;  Q7XR60, MTK2_ORYSJ ;  Q9C6D2, MTK_ARATH  ;
DR   A7Z3X1, MTNK_BACA2 ;  C3P742, MTNK_BACAA ;  C3LIA3, MTNK_BACAC ;
DR   A0RI39, MTNK_BACAH ;  Q81MJ5, MTNK_BACAN ;  B7JL13, MTNK_BACC0 ;
DR   Q731R6, MTNK_BACC1 ;  B7IWE5, MTNK_BACC2 ;  C1EQQ8, MTNK_BACC3 ;
DR   B7H924, MTNK_BACC4 ;  B7HN10, MTNK_BACC7 ;  A7GS57, MTNK_BACCN ;
DR   B9IWP6, MTNK_BACCQ ;  Q819F1, MTNK_BACCR ;  Q635P6, MTNK_BACCZ ;
DR   Q6HED2, MTNK_BACHK ;  Q65KK1, MTNK_BACLD ;  A8FCG6, MTNK_BACP2 ;
DR   O31663, MTNK_BACSU ;  A9VFD6, MTNK_BACWK ;  A8ANI4, MTNK_CITK8 ;
DR   A4W7Z0, MTNK_ENT38 ;  A7MKY0, MTNK_ENTS8 ;  Q6D1H0, MTNK_ERWCT ;
DR   B2VIQ9, MTNK_ERWT9 ;  B1YIY3, MTNK_EXIS2 ;  Q5L1E5, MTNK_GEOKA ;
DR   C5D7U6, MTNK_GEOSW ;  A4ILL2, MTNK_GEOTN ;  B5XZW3, MTNK_KLEP3 ;
DR   A6T655, MTNK_KLEP7 ;  Q9F0P1, MTNK_KLEPN ;  C6DCZ0, MTNK_PECCP ;
DR   A8GAB2, MTNK_SERP5 ;  A1JP08, MTNK_YERE8 ;  A7FLL0, MTNK_YERP3 ;
DR   B2K634, MTNK_YERPB ;  A9R2Z4, MTNK_YERPG ;  A4TPM8, MTNK_YERPP ;
DR   Q66E15, MTNK_YERPS ;  B1JIK2, MTNK_YERPY ;
//
ID   2.7.1.101
DE   Tagatose kinase.
AN   D-tagatose 6-phosphate kinase.
CA   ATP + D-tagatose = ADP + D-tagatose 6-phosphate.
//
ID   2.7.1.102
DE   Hamamelose kinase.
CA   ATP + D-hamamelose = ADP + D-hamamelose 2'-phosphate.
CC   -!- Also acts, more slowly, on D-hamamelitol.
//
ID   2.7.1.103
DE   Viomycin kinase.
AN   Capreomycin phosphotransferase.
AN   Viomycin phosphotransferase.
CA   ATP + viomycin = ADP + O-phosphoviomycin.
CC   -!- Also acts on capreomycins.
CC   -!- A serine residue in the peptide antibiotics acts as phosphate-
CC       acceptor.
DR   P18623, VPH_STRVI  ;
//
ID   2.7.1.104
DE   Transferred entry: 2.7.99.1.
//
ID   2.7.1.105
DE   6-phosphofructo-2-kinase.
AN   Phosphofructokinase 2.
CA   ATP + D-fructose 6-phosphate = ADP + beta-D-fructose 2,6-bisphosphate.
CC   -!- Not identical with EC 2.7.1.11.
CC   -!- The enzyme copurifies with EC 3.1.3.46.
PR   PROSITE; PDOC00158;
DR   P40433, 6P21_YEAST ;  Q12471, 6P22_YEAST ;  P49872, F261_BOVIN ;
DR   P16118, F261_HUMAN ;  P70266, F261_MOUSE ;  P07953, F261_RAT   ;
DR   P26285, F262_BOVIN ;  O60825, F262_HUMAN ;  P70265, F262_MOUSE ;
DR   Q5NVT1, F262_PONAB ;  Q9JJH5, F262_RAT   ;  Q28901, F263_BOVIN ;
DR   Q16875, F263_HUMAN ;  Q5R9C1, F263_PONAB ;  O35552, F263_RAT   ;
DR   Q16877, F264_HUMAN ;  Q4R8B6, F264_MACFA ;  Q6DTY7, F264_MOUSE ;
DR   P25114, F264_RAT   ;  Q91348, F26L_CHICK ;  Q21122, F26_CAEEL  ;
DR   Q91309, F26_RANCA  ;  Q9UTE1, YFMD_SCHPO ;  Q8TFH0, YIKE_SCHPO ;
DR   Q9UTK9, YIVH_SCHPO ;  Q06137, YL345_YEAST;
//
ID   2.7.1.106
DE   Glucose-1,6-bisphosphate synthase.
AN   Glucose 1,6-diphosphate synthase.
AN   Glucose-1,6-bisphosphate synthetase.
CA   3-phospho-D-glyceroyl phosphate + alpha-D-glucose 1-phosphate =
CA   3-phospho-D-glycerate + alpha-D-glucose 1,6-bisphosphate.
CC   -!- Alpha-D-glucose 6-phosphate can act as acceptor, forming alpha-D-
CC       glucose 1,6-bisphosphate.
DR   Q6PCE3, PGM2L_HUMAN;  Q8CAA7, PGM2L_MOUSE;  Q5R979, PGM2L_PONAB;
//
ID   2.7.1.107
DE   Diacylglycerol kinase.
AN   DGK.
AN   Diglyceride kinase.
CA   ATP + 1,2-diacylglycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.
PR   PROSITE; PDOC00820;
PR   PROSITE; PDOC50146;
DR   Q7ZW00, AGK_DANRE  ;  Q53H12, AGK_HUMAN  ;  Q9ESW4, AGK_MOUSE  ;
DR   Q5RED7, AGK_PONAB  ;  Q7ZYJ3, AGK_XENLA  ;  O31502, DAGK_BACSU ;
DR   O53526, DAGK_MYCTU ;  A7X424, DAGK_STAA1 ;  A6U302, DAGK_STAA2 ;
DR   Q2FFJ7, DAGK_STAA3 ;  Q2FWZ2, DAGK_STAA8 ;  A5IU64, DAGK_STAA9 ;
DR   Q2YU29, DAGK_STAAB ;  Q5HEM4, DAGK_STAAC ;  A6QIC6, DAGK_STAAE ;
DR   Q99SY8, DAGK_STAAM ;  Q7A4Q8, DAGK_STAAN ;  Q6GFF9, DAGK_STAAR ;
DR   Q6G835, DAGK_STAAS ;  A8Z2R1, DAGK_STAAT ;  Q7A0H3, DAGK_STAAW ;
DR   B9DMT6, DAGK_STACT ;  Q5HN36, DAGK_STAEQ ;  Q8CRU5, DAGK_STAES ;
DR   Q4L7L1, DAGK_STAHJ ;  Q49YU2, DAGK_STAS1 ;  Q39017, DGK1_ARATH ;
DR   Q01583, DGK1_DROME ;  Q09103, DGK2_DROME ;  Q03603, DGK3_CAEEL ;
DR   Q10024, DGK5_CAEEL ;  A0JN54, DGKA_BOVIN ;  P34125, DGKA_DICDI ;
DR   P23743, DGKA_HUMAN ;  O88673, DGKA_MOUSE ;  P20192, DGKA_PIG   ;
DR   P51556, DGKA_RAT   ;  Q9Y6T7, DGKB_HUMAN ;  Q6NS52, DGKB_MOUSE ;
DR   P49621, DGKB_RAT   ;  Q16760, DGKD_HUMAN ;  P52429, DGKE_HUMAN ;
DR   Q9R1C6, DGKE_MOUSE ;  P49619, DGKG_HUMAN ;  Q91WG7, DGKG_MOUSE ;
DR   P49620, DGKG_RAT   ;  B3LXF2, DGKH_DROAN ;  B3NYS4, DGKH_DROER ;
DR   B4JHJ7, DGKH_DROGR ;  A8JQ65, DGKH_DROME ;  B4K6T8, DGKH_DROMO ;
DR   B4I4Y1, DGKH_DROSE ;  B4R0A5, DGKH_DROSI ;  B4PRE2, DGKH_DROYA ;
DR   Q86XP1, DGKH_HUMAN ;  Q64398, DGKH_MESAU ;  O75912, DGKI_HUMAN ;
DR   Q5KSL6, DGKK_HUMAN ;  P52824, DGKQ_HUMAN ;  Q6P5E8, DGKQ_MOUSE ;
DR   Q13574, DGKZ_HUMAN ;  Q80UP3, DGKZ_MOUSE ;  O08560, DGKZ_RAT   ;
DR   P0ABN3, KDGL_ECO57 ;  P0ABN2, KDGL_ECOL6 ;  P0ABN1, KDGL_ECOLI ;
DR   P44424, KDGL_HAEIN ;  Q9ZLE0, KDGL_HELPJ ;  P56411, KDGL_HELPY ;
DR   Q9HY23, KDGL_PSEAE ;  P29945, KDGL_PSEDE ;  Q06119, KDGL_RHIME ;
DR   P0ABN4, KDGL_SHIFL ;  Q55143, KDGL_SYNY3 ;
//
ID   2.7.1.108
DE   Dolichol kinase.
CA   CTP + dolichol = CDP + dolichyl phosphate.
DR   Q58CR4, DOLK_BOVIN ;  Q9UPQ8, DOLK_HUMAN ;  Q8R2Y3, DOLK_MOUSE ;
DR   P20048, SEC59_YEAST;
//
ID   2.7.1.109
DE   Transferred entry: 2.7.11.31.
//
ID   2.7.1.110
DE   Transferred entry: 2.7.11.3.
//
ID   2.7.1.111
DE   Transferred entry: 2.7.11.27.
//
ID   2.7.1.112
DE   Transferred entry: 2.7.10.1 and 2.7.10.2.
//
ID   2.7.1.113
DE   Deoxyguanosine kinase.
CA   ATP + deoxyguanosine = ADP + dGMP.
CC   -!- Deoxyinosine can also act as acceptor.
DR   P0C1G0, DGK2_LACAC ;  Q74HC2, DGK2_LACJO ;  P37530, DGK_BACSU  ;
DR   Q54UT2, DGK_DICDI  ;  Q16854, DGUOK_HUMAN;  Q9QX60, DGUOK_MOUSE;
//
ID   2.7.1.114
DE   AMP--thymidine kinase.
AN   Adenylate-nucleoside phosphotransferase.
CA   AMP + thymidine = adenosine + thymidine 5'-phosphate.
CC   -!- The deoxypyrimidine kinase complex induced by Herpes simplex virus
CC       catalyzes this reaction as well as those of EC 2.7.1.21,
CC       EC 2.7.1.128, and EC 2.7.4.9.
//
ID   2.7.1.115
DE   Transferred entry: 2.7.11.4.
//
ID   2.7.1.116
DE   Transferred entry: 2.7.11.5.
//
ID   2.7.1.117
DE   Transferred entry: 2.7.11.18.
//
ID   2.7.1.118
DE   ADP--thymidine kinase.
CA   ADP + thymidine = AMP + thymidine 5'-phosphate.
CC   -!- The deoxypyrimidine kinase complex induced by Herpes simplex virus
CC       catalyzes this reaction as well as those of EC 2.7.1.21, EC 2.7.1.114
CC       and EC 2.7.4.9.
//
ID   2.7.1.119
DE   Hygromycin-B 7''-O-kinase.
AN   APH(7'').
AN   Hygromycin B phosphotransferase.
AN   Hygromycin-B kinase.
CA   ATP + hygromycin B = ADP + 7''-O-phosphohygromycin.
CC   -!- Phosphorylates the antibiotics hygromycin B, 1-N-hygromycin B and
CC       destomycin, but not hygromycin B2, at the 7''-hydroxy group in the
CC       destomic acid ring.
DR   P09979, KHYB_STRHY ;
//
ID   2.7.1.120
DE   Transferred entry: 2.7.11.17.
//
ID   2.7.1.121
DE   Phosphoenolpyruvate--glycerone phosphotransferase.
CA   Phosphoenolpyruvate + glycerone = pyruvate + glycerone phosphate.
//
ID   2.7.1.122
DE   Xylitol kinase.
AN   Xylitol phosphotransferase.
CA   ATP + xylitol = ADP + xylitol 5-phosphate.
//
ID   2.7.1.123
DE   Transferred entry: 2.7.11.17.
//
ID   2.7.1.124
DE   Transferred entry: 2.7.11.6.
//
ID   2.7.1.125
DE   Transferred entry: 2.7.11.14.
//
ID   2.7.1.126
DE   Transferred entry: 2.7.11.15.
//
ID   2.7.1.127
DE   Inositol-trisphosphate 3-kinase.
AN   1D-myo-inositol-trisphosphate 3-kinase.
AN   Inositol 1,4,5-trisphosphate 3-kinase.
AN   Ins(1,4,5)P(3) 3-kinase.
AN   IP3 3-kinase.
AN   IP3K.
CA   ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol
CA   1,3,4,5-tetrakisphosphate.
CF   Calcium.
DR   P23677, IP3KA_HUMAN;  Q8R071, IP3KA_MOUSE;  P17105, IP3KA_RAT  ;
DR   P27987, IP3KB_HUMAN;  P42335, IP3KB_RAT  ;  Q96DU7, IP3KC_HUMAN;
DR   Q7TS72, IP3KC_MOUSE;  Q80ZG2, IP3KC_RAT  ;
//
ID   2.7.1.128
DE   Transferred entry: 2.7.11.27.
//
ID   2.7.1.129
DE   Transferred entry: 2.7.11.7.
//
ID   2.7.1.130
DE   Tetraacyldisaccharide 4'-kinase.
AN   Lipid-A 4'-kinase.
CA   ATP + (2-N,3-O-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl)-(1->6)-
CA   (2-N,3-O-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl phosphate) =
CA   ADP + (2-N,3-O-bis(3-hydroxytetradecanoyl)-4-O-phosphono-beta-D-
CA   glucosaminyl)-(1->6)-(2-N,3-O-bis(3-hydroxytetradecanoyl)-beta-D-
CA   glucosaminyl phosphate).
CC   -!- Involved with EC 2.3.1.129 and 2.4.1.182 in the biosynthesis of the
CC       phosphorylated glycolipid, lipid A, in the outer membrane of
CC       Escherichia coli.
DR   Q1IHD2, LPXK_ACIBL ;  B9MI83, LPXK_ACIET ;  B7J512, LPXK_ACIF2 ;
DR   B5EMX2, LPXK_ACIF5 ;  A1W892, LPXK_ACISJ ;  A3N1S8, LPXK_ACTP2 ;
DR   B3H250, LPXK_ACTP7 ;  B0BQL1, LPXK_ACTPJ ;  A6VQ32, LPXK_ACTSZ ;
DR   A0KLY1, LPXK_AERHH ;  A4SL68, LPXK_AERS4 ;  B9JA09, LPXK_AGRRK ;
DR   Q8UHI5, LPXK_AGRT5 ;  B9JSD8, LPXK_AGRVS ;  Q0VQP4, LPXK_ALCBS ;
DR   Q0A8Q4, LPXK_ALHEH ;  B6ES04, LPXK_ALISL ;  B8JE66, LPXK_ANAD2 ;
DR   Q2IL55, LPXK_ANADE ;  A7HDI5, LPXK_ANADF ;  B4UHQ4, LPXK_ANASK ;
DR   O67572, LPXK_AQUAE ;  A8EU81, LPXK_ARCB4 ;  Q5P108, LPXK_AROAE ;
DR   A8I6A3, LPXK_AZOC5 ;  A1K5I2, LPXK_AZOSB ;  C1DR19, LPXK_AZOVD ;
DR   Q5LAA4, LPXK_BACFN ;  Q64QN6, LPXK_BACFR ;  Q8A6K1, LPXK_BACTN ;
DR   A6L0S5, LPXK_BACV8 ;  A1UU03, LPXK_BARBK ;  Q6G4R6, LPXK_BARHE ;
DR   Q6G0J6, LPXK_BARQU ;  A9IN76, LPXK_BART1 ;  Q6MMX4, LPXK_BDEBA ;
DR   Q7VR45, LPXK_BLOFL ;  Q492T0, LPXK_BLOPB ;  Q2KZE8, LPXK_BORA1 ;
DR   Q7WKU5, LPXK_BORBR ;  Q7W7F7, LPXK_BORPA ;  A9IQ28, LPXK_BORPD ;
DR   Q7VVB2, LPXK_BORPE ;  Q89DC5, LPXK_BRAJA ;  A5ECK7, LPXK_BRASB ;
DR   A4Z0S1, LPXK_BRASO ;  B2SD13, LPXK_BRUA1 ;  Q2YIH4, LPXK_BRUA2 ;
DR   Q579M9, LPXK_BRUAB ;  A9MDX1, LPXK_BRUC2 ;  C0RKF4, LPXK_BRUMB ;
DR   P65325, LPXK_BRUME ;  A5VTV9, LPXK_BRUO2 ;  A9WXS0, LPXK_BRUSI ;
DR   P65326, LPXK_BRUSU ;  B1YVD7, LPXK_BURA4 ;  Q1BU69, LPXK_BURCA ;
DR   B1JXF5, LPXK_BURCC ;  A0K9W8, LPXK_BURCH ;  B4E9F8, LPXK_BURCJ ;
DR   Q0BCH4, LPXK_BURCM ;  A9AGK4, LPXK_BURM1 ;  Q3JVA8, LPXK_BURP1 ;
DR   Q63WL3, LPXK_BURPS ;  Q39DJ6, LPXK_BURS3 ;  Q2T0K1, LPXK_BURTA ;
DR   A4JH77, LPXK_BURVG ;  Q13US1, LPXK_BURXL ;  A8Z6M1, LPXK_CAMC1 ;
DR   A8FLM4, LPXK_CAMJ8 ;  A7H438, LPXK_CAMJD ;  Q9PPA9, LPXK_CAMJE ;
DR   A1VZF9, LPXK_CAMJJ ;  Q5HUY1, LPXK_CAMJR ;  B8GYH3, LPXK_CAUCN ;
DR   P58184, LPXK_CAUCR ;  B0T114, LPXK_CAUSK ;  Q5L6Q2, LPXK_CHLAB ;
DR   Q3AU78, LPXK_CHLCH ;  Q824D6, LPXK_CHLCV ;  B3EG23, LPXK_CHLL2 ;
DR   Q9PJZ4, LPXK_CHLMU ;  B3QLP5, LPXK_CHLP8 ;  A1BDV6, LPXK_CHLPD ;
DR   Q9Z823, LPXK_CHLPN ;  Q8KBV6, LPXK_CHLTE ;  O84407, LPXK_CHLTR ;
DR   Q7NSS4, LPXK_CHRVO ;  A8AIG6, LPXK_CITK8 ;  Q483B5, LPXK_COLP3 ;
DR   B6J6T1, LPXK_COXB1 ;  B6J0K1, LPXK_COXB2 ;  A9KFL0, LPXK_COXBN ;
DR   A9ND59, LPXK_COXBR ;  Q83D83, LPXK_COXBU ;  Q0KE17, LPXK_CUPNH ;
DR   Q475F8, LPXK_CUPPJ ;  Q11U43, LPXK_CYTH3 ;  Q47B43, LPXK_DECAR ;
DR   A9BWI4, LPXK_DELAS ;  B8F928, LPXK_DESAA ;  Q30Y50, LPXK_DESDG ;
DR   Q6ALV8, LPXK_DESPS ;  Q728Y4, LPXK_DESVH ;  B8DP49, LPXK_DESVM ;
DR   A5EYE3, LPXK_DICNV ;  A8LJV4, LPXK_DINSH ;  A7ZK04, LPXK_ECO24 ;
DR   B7UN01, LPXK_ECO27 ;  B7MHM4, LPXK_ECO45 ;  B7LE13, LPXK_ECO55 ;
DR   Q8XDH0, LPXK_ECO57 ;  B5YT49, LPXK_ECO5E ;  B7NM59, LPXK_ECO7I ;
DR   B7MS30, LPXK_ECO81 ;  B7M844, LPXK_ECO8A ;  C4ZQ41, LPXK_ECOBW ;
DR   B1X855, LPXK_ECODH ;  A7ZYL7, LPXK_ECOHS ;  A1A9J2, LPXK_ECOK1 ;
DR   Q0TJD8, LPXK_ECOL5 ;  B1IW16, LPXK_ECOLC ;  P27300, LPXK_ECOLI ;
DR   B7NAR4, LPXK_ECOLU ;  B6I8Y7, LPXK_ECOSE ;  B1LJU8, LPXK_ECOSM ;
DR   Q1RDU3, LPXK_ECOUT ;  C5BAE1, LPXK_EDWI9 ;  B2KC48, LPXK_ELUMP ;
DR   A4W8T4, LPXK_ENT38 ;  A7MET8, LPXK_ENTS8 ;  Q6D438, LPXK_ERWCT ;
DR   B2VC73, LPXK_ERWT9 ;  B7LN77, LPXK_ESCF3 ;  A5FNE6, LPXK_FLAJ1 ;
DR   A6GZM3, LPXK_FLAPJ ;  Q47909, LPXK_FRANO ;  B0TWX8, LPXK_FRAP2 ;
DR   Q14JW5, LPXK_FRAT1 ;  A7NE36, LPXK_FRATF ;  Q2A1V0, LPXK_FRATH ;
DR   B2SF15, LPXK_FRATM ;  A0Q8A0, LPXK_FRATN ;  Q0BKJ4, LPXK_FRATO ;
DR   Q5NIG2, LPXK_FRATT ;  A4IW67, LPXK_FRATW ;  Q39T52, LPXK_GEOMG ;
DR   Q74AU2, LPXK_GEOSL ;  C6E5B2, LPXK_GEOSM ;  A5G6H1, LPXK_GEOUR ;
DR   A9H0Y0, LPXK_GLUDA ;  Q5FPH6, LPXK_GLUOX ;  Q7VP80, LPXK_HAEDU ;
DR   Q4QPI5, LPXK_HAEI8 ;  A5UB80, LPXK_HAEIE ;  P44491, LPXK_HAEIN ;
DR   Q0I2X7, LPXK_HAES1 ;  B0UT77, LPXK_HAES2 ;  Q2SIN4, LPXK_HAHCH ;
DR   A1WWF8, LPXK_HALHL ;  B8CZC3, LPXK_HALOH ;  C4K356, LPXK_HAMD5 ;
DR   Q17X64, LPXK_HELAH ;  Q1CUH3, LPXK_HELPH ;  Q9ZMB1, LPXK_HELPJ ;
DR   O25095, LPXK_HELPY ;  A4G7Y1, LPXK_HERAR ;  Q0C4B4, LPXK_HYPNA ;
DR   Q5QU37, LPXK_IDILO ;  A6T172, LPXK_JANMA ;  Q28VE6, LPXK_JANSC ;
DR   A6T707, LPXK_KLEP7 ;  Q5X499, LPXK_LEGPA ;  A5ICX5, LPXK_LEGPC ;
DR   Q5ZUI0, LPXK_LEGPH ;  Q5WVN3, LPXK_LEGPL ;  B0SDY8, LPXK_LEPBA ;
DR   B0SMC0, LPXK_LEPBP ;  B1Y6I4, LPXK_LEPCP ;  Q2VZS8, LPXK_MAGSA ;
DR   Q65U20, LPXK_MANSM ;  Q0AS12, LPXK_MARMM ;  Q11L82, LPXK_MESSB ;
DR   B7KT03, LPXK_METC4 ;  Q60B49, LPXK_METCA ;  A9W6S6, LPXK_METEP ;
DR   Q1GZI1, LPXK_METFK ;  B8IPK9, LPXK_METNO ;  B1ZHI5, LPXK_METPB ;
DR   A2SIQ1, LPXK_METPP ;  B1LYS1, LPXK_METRJ ;  B0UJ62, LPXK_METS4 ;
DR   Q5F9Z2, LPXK_NEIG1 ;  A9M2V4, LPXK_NEIM0 ;  Q9JVE4, LPXK_NEIMA ;
DR   Q9K0D7, LPXK_NEIMB ;  A1KST3, LPXK_NEIMF ;  Q0AEA0, LPXK_NITEC ;
DR   Q82SY2, LPXK_NITEU ;  Q1QIN5, LPXK_NITHX ;  Q3J7R7, LPXK_NITOC ;
DR   Q3SPI3, LPXK_NITWN ;  A6X3F1, LPXK_OCHA4 ;  B6JIX8, LPXK_OLICO ;
DR   A6LIV7, LPXK_PARD8 ;  A1B3U2, LPXK_PARDP ;  A7HQR4, LPXK_PARL1 ;
DR   Q9CMG8, LPXK_PASMU ;  C6DFA2, LPXK_PECCP ;  Q3A547, LPXK_PELCD ;
DR   Q3B2C2, LPXK_PELLD ;  B4SDV3, LPXK_PELPB ;  A1ATF5, LPXK_PELPD ;
DR   Q4FPB7, LPXK_PELUB ;  B4REI3, LPXK_PHEZH ;  Q7N6C5, LPXK_PHOLL ;
DR   Q6LPK7, LPXK_PHOPR ;  A1VNK5, LPXK_POLNA ;  B1XTC8, LPXK_POLNS ;
DR   Q129C9, LPXK_POLSJ ;  A4SVJ1, LPXK_POLSQ ;  B2RIK3, LPXK_PORG3 ;
DR   Q7MWH4, LPXK_PORGI ;  B4ET31, LPXK_PROMH ;  A4SG46, LPXK_PROVI ;
DR   Q48L54, LPXK_PSE14 ;  Q15UY6, LPXK_PSEA6 ;  A6V3B7, LPXK_PSEA7 ;
DR   B7V147, LPXK_PSEA8 ;  Q02PE4, LPXK_PSEAB ;  Q9HZM3, LPXK_PSEAE ;
DR   Q1ID01, LPXK_PSEE4 ;  Q4KFT5, LPXK_PSEF5 ;  C3JY29, LPXK_PSEFS ;
DR   Q3IGX6, LPXK_PSEHT ;  A4XSR2, LPXK_PSEMY ;  A5W728, LPXK_PSEP1 ;
DR   Q3K8J2, LPXK_PSEPF ;  B0KF41, LPXK_PSEPG ;  Q88LM9, LPXK_PSEPK ;
DR   B1J506, LPXK_PSEPW ;  Q87YF5, LPXK_PSESM ;  Q4ZVY9, LPXK_PSEU2 ;
DR   A4VMT5, LPXK_PSEU5 ;  Q4FS43, LPXK_PSYA2 ;  Q1QBV9, LPXK_PSYCK ;
DR   A1STC8, LPXK_PSYIN ;  Q1LR05, LPXK_RALME ;  Q8XWE4, LPXK_RALSO ;
DR   B3PRD6, LPXK_RHIE6 ;  Q2KBX9, LPXK_RHIEC ;  Q1MKV3, LPXK_RHIL3 ;
DR   P58185, LPXK_RHILO ;  B5ZRZ4, LPXK_RHILW ;  Q92RP7, LPXK_RHIME ;
DR   C3MGV8, LPXK_RHISN ;  Q7UNW7, LPXK_RHOBA ;  B6IXD8, LPXK_RHOCS ;
DR   Q21TN9, LPXK_RHOFD ;  Q2IYZ6, LPXK_RHOP2 ;  Q07T97, LPXK_RHOP5 ;
DR   Q6NAM5, LPXK_RHOPA ;  Q20XB0, LPXK_RHOPB ;  Q131B2, LPXK_RHOPS ;
DR   B3QIG6, LPXK_RHOPT ;  Q2RWV9, LPXK_RHORT ;  A3PFW7, LPXK_RHOS1 ;
DR   Q3J6I0, LPXK_RHOS4 ;  A4WNK8, LPXK_RHOS5 ;  B9KR99, LPXK_RHOSK ;
DR   C3PLI9, LPXK_RICAE ;  A8GPM5, LPXK_RICAH ;  A8GXU5, LPXK_RICB8 ;
DR   Q1RK48, LPXK_RICBR ;  A8EZT1, LPXK_RICCK ;  Q92GN1, LPXK_RICCN ;
DR   Q4UN11, LPXK_RICFE ;  A8F2K3, LPXK_RICM5 ;  P58186, LPXK_RICMO ;
DR   Q9ZCL0, LPXK_RICPR ;  C4K0S8, LPXK_RICPU ;  P58187, LPXK_RICRI ;
DR   B0BUY7, LPXK_RICRO ;  A8GTE9, LPXK_RICRS ;  P58188, LPXK_RICTY ;
DR   Q16DC4, LPXK_ROSDO ;  A1AXA3, LPXK_RUTMC ;  Q21J10, LPXK_SACD2 ;
DR   B5F168, LPXK_SALA4 ;  A9MHW7, LPXK_SALAR ;  Q57R13, LPXK_SALCH ;
DR   B5FQ58, LPXK_SALDC ;  B5QZB9, LPXK_SALEP ;  B5R8K2, LPXK_SALG2 ;
DR   B4TDQ2, LPXK_SALHS ;  B4T149, LPXK_SALNS ;  Q5PGH1, LPXK_SALPA ;
DR   A9N7U7, LPXK_SALPB ;  C0PXV2, LPXK_SALPC ;  B5BBP3, LPXK_SALPK ;
DR   B4TRU7, LPXK_SALSV ;  Q8Z801, LPXK_SALTI ;  Q8ZQC2, LPXK_SALTY ;
DR   A8GCH7, LPXK_SERP5 ;  A1S589, LPXK_SHEAM ;  A3D382, LPXK_SHEB5 ;
DR   A6WLX5, LPXK_SHEB8 ;  A9KXE0, LPXK_SHEB9 ;  Q12M47, LPXK_SHEDO ;
DR   Q080T3, LPXK_SHEFN ;  B0TK43, LPXK_SHEHH ;  A3QDF8, LPXK_SHELP ;
DR   Q8EDF1, LPXK_SHEON ;  A8H3F7, LPXK_SHEPA ;  A4Y5Q0, LPXK_SHEPC ;
DR   B8CNQ5, LPXK_SHEPW ;  A0KYE1, LPXK_SHESA ;  A8FX59, LPXK_SHESH ;
DR   Q0HHH5, LPXK_SHESM ;  Q0HTS9, LPXK_SHESR ;  A1RL20, LPXK_SHESW ;
DR   B1KNM7, LPXK_SHEWM ;  B2TUG4, LPXK_SHIB3 ;  Q31YT5, LPXK_SHIBS ;
DR   Q32E35, LPXK_SHIDS ;  Q0SX00, LPXK_SHIF8 ;  Q83RY7, LPXK_SHIFL ;
DR   Q3Z3K6, LPXK_SHISS ;  Q5LMW7, LPXK_SILPO ;  Q1GD92, LPXK_SILST ;
DR   A6U6K3, LPXK_SINMW ;  Q2NUA4, LPXK_SODGM ;  B4SQP9, LPXK_STRM5 ;
DR   B2FK22, LPXK_STRMK ;  Q2LVL1, LPXK_SYNAS ;  A0LF44, LPXK_SYNFM ;
DR   Q31H20, LPXK_THICR ;  Q3SIR4, LPXK_THIDA ;  C4L8W2, LPXK_TOLAT ;
DR   A1WSH4, LPXK_VEREI ;  A5CVZ9, LPXK_VESOH ;  A5F728, LPXK_VIBC3 ;
DR   Q9KQX0, LPXK_VIBCH ;  Q5E0F1, LPXK_VIBF1 ;  B5ETK5, LPXK_VIBFM ;
DR   A7MV09, LPXK_VIBHB ;  Q87R15, LPXK_VIBPA ;  B7VH37, LPXK_VIBSL ;
DR   Q8DAV1, LPXK_VIBVU ;  Q7MJ08, LPXK_VIBVY ;  Q8D2U9, LPXK_WIGBR ;
DR   Q7MSR3, LPXK_WOLSU ;  Q8PKS4, LPXK_XANAC ;  Q3BTC7, LPXK_XANC5 ;
DR   Q4UV64, LPXK_XANC8 ;  B0RSH9, LPXK_XANCB ;  Q8P8W5, LPXK_XANCP ;
DR   Q2P3E8, LPXK_XANOM ;  B2SKI3, LPXK_XANOP ;  Q5H0H1, LPXK_XANOR ;
DR   A7IFD6, LPXK_XANP2 ;  B2I804, LPXK_XYLF2 ;  Q9PEE6, LPXK_XYLFA ;
DR   B0U4R4, LPXK_XYLFM ;  Q87EE9, LPXK_XYLFT ;  A1JMK0, LPXK_YERE8 ;
DR   A7FJW3, LPXK_YERP3 ;  Q1CA67, LPXK_YERPA ;  B2KA30, LPXK_YERPB ;
DR   Q8ZGA8, LPXK_YERPE ;  A9R7I8, LPXK_YERPG ;  Q1CGH1, LPXK_YERPN ;
DR   A4TN12, LPXK_YERPP ;  Q66CI2, LPXK_YERPS ;  B1JRD3, LPXK_YERPY ;
//
ID   2.7.1.131
DE   Transferred entry: 2.7.11.29.
//
ID   2.7.1.132
DE   Transferred entry: 2.7.11.28.
//
ID   2.7.1.133
DE   Transferred entry: 2.7.1.134.
//
ID   2.7.1.134
DE   Inositol-tetrakisphosphate 1-kinase.
AN   1D-myo-inositol-tetrakisphosphate 1-kinase.
AN   1D-myo-inositol-trisphosphate 5-kinase.
AN   1D-myo-inositol-trisphosphate 6-kinase.
AN   Inositol-trisphosphate 5-kinase.
AN   Inositol-trisphosphate 6-kinase.
CA   ATP + 1D-myo-inositol 3,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol
CA   1,3,4,5,6-pentakisphosphate.
CC   -!- This enzyme also phosphorylates Ins(1,3,4)P(3) on O-5 and O-6.
CC   -!- The phosphotransfer from ATP to either inositol 1,3,4-trisphosphate
CC       or inositol 3,4,5,6-tetrakisphosphate appears to be freely reversible
CC       to the extent that the enzyme can act like an inositol polyphosphate
CC       phosphatase in the presence of ADP.
CC   -!- It can also catalyze an isomerization between Ins(1,3,4,5)P(4) and
CC       Ins(1,3,4,6)P(4) in the presence of ADP.
CC   -!- Formerly EC 2.7.1.133 and EC 2.7.1.139.
PR   PROSITE; PDOC50975;
DR   Q9SBA5, ITPK1_ARATH;  P0C0T1, ITPK1_BOVIN;  Q5F480, ITPK1_CHICK;
DR   Q7ZU91, ITPK1_DANRE;  Q9XYQ1, ITPK1_ENTHI;  Q13572, ITPK1_HUMAN;
DR   Q84Y01, ITPK1_MAIZE;  Q8BYN3, ITPK1_MOUSE;  Q7SY78, ITPK1_XENLA;
DR   Q9SUG3, ITPK2_ARATH;  O81893, ITPK3_ARATH;  O80568, ITPK4_ARATH;
//
ID   2.7.1.135
DE   Transferred entry: 2.7.11.26.
//
ID   2.7.1.136
DE   Macrolide 2'-kinase.
CA   ATP + oleandomycin = ADP + oleandomycin 2'-O-phosphate.
CC   -!- Erythromycin, spiramycin and some other macrolide antibiotics can
CC       also act as acceptors.
//
ID   2.7.1.137
DE   Phosphatidylinositol 3-kinase.
AN   1-phosphatidylinositol 3-kinase.
AN   PI3-kinase.
AN   PtdIns-3-kinase.
AN   Type I phosphatidylinositol kinase.
AN   Type III phosphoinositide 3-kinase.
CA   ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-
CA   inositol 3-phosphate.
PR   PROSITE; PDOC00710;
DR   P0C5E7, AGE1_CAEBR ;  Q94125, AGE1_CAEEL ;  P54673, PI3K1_DICDI;
DR   P42347, PI3K1_SOYBN;  P54674, PI3K2_DICDI;  P42348, PI3K2_SOYBN;
DR   P54675, PI3K3_DICDI;  P54676, PI3K4_DICDI;  P42339, PI3K_ARATH ;
DR   Q8NEB9, PK3C3_HUMAN;  Q6PF93, PK3C3_MOUSE;  Q5D891, PK3C3_PIG  ;
DR   O88763, PK3C3_RAT  ;  Q6AZN6, PK3C3_XENLA;  O14356, TOR1_SCHPO ;
DR   Q9Y7K2, TOR2_SCHPO ;  Q92213, VPS34_CANAL;  Q8SR56, VPS34_ENCCU;
DR   P50520, VPS34_SCHPO;  P22543, VPS34_YEAST;
//
ID   2.7.1.138
DE   Ceramide kinase.
AN   Acylsphingosine kinase.
CA   ATP + ceramide = ADP + ceramide 1-phosphate.
PR   PROSITE; PDOC50146;
DR   Q8TCT0, CERK1_HUMAN;  Q8K4Q7, CERK1_MOUSE;
//
ID   2.7.1.139
DE   Transferred entry: 2.7.1.134.
//
ID   2.7.1.140
DE   Inositol-tetrakisphosphate 5-kinase.
AN   1D-myo-inositol-tetrakisphosphate 5-kinase.
CA   ATP + 1D-myo-inositol 1,3,4,6-tetrakisphosphate = ADP + 1D-myo-inositol
CA   1,3,4,5,6-pentakisphosphate.
CC   -!- The enzyme from plants and yeast can also use Ins(1,2,3,4,6)P(5) as a
CC       substrate.
DR   Q9LY23, IPMKA_ARATH;  Q9FLT2, IPMKB_ARATH;
//
ID   2.7.1.141
DE   Transferred entry: 2.7.11.23.
//
ID   2.7.1.142
DE   Glycerol-3-phosphate--glucose phosphotransferase.
CA   sn-glycerol 3-phosphate + D-glucose = glycerol + D-glucose 6-phosphate.
CC   -!- Involved in the anaerobic metabolism of sugars in the bloodstream of
CC       trypanosomes.
//
ID   2.7.1.143
DE   Diphosphate-purine nucleoside kinase.
AN   Diphosphate-dependent nucleoside kinase.
AN   Pyrophosphate-dependent nucleoside kinase.
AN   Pyrophosphate-purine nucleoside kinase.
CA   Diphosphate + a purine nucleoside = phosphate + a purine mononucleotide.
CC   -!- The enzyme from the Acholeplasma class of Mollicutes catalyzes the
CC       conversion of adenosine, guanosine and inosine to AMP, GMP and IMP.
CC   -!- ATP cannot substitute for diphosphate as a substrate.
//
ID   2.7.1.144
DE   Tagatose-6-phosphate kinase.
AN   Phosphotagatokinase.
CA   ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate.
PR   PROSITE; PDOC00504;
DR   Q8E4R7, LACC1_STRA3;  Q8E346, LACC2_STRA3;  Q8XNK5, LACC_CLOPE ;
DR   Q833W9, LACC_ENTFA ;  P23391, LACC_LACLA ;  A7X575, LACC_STAA1 ;
DR   A6U3S3, LACC_STAA2 ;  Q2FET9, LACC_STAA3 ;  P0A0B9, LACC_STAA8 ;
DR   A5IUY2, LACC_STAA9 ;  Q2YYJ5, LACC_STAAB ;  Q5HE12, LACC_STAAC ;
DR   A6QJ37, LACC_STAAE ;  P65698, LACC_STAAM ;  P65699, LACC_STAAN ;
DR   Q6GEN6, LACC_STAAR ;  Q6G7C1, LACC_STAAS ;  A8YYG0, LACC_STAAT ;
DR   P0A0B8, LACC_STAAW ;  Q5HM37, LACC_STAEQ ;  Q8CRJ4, LACC_STAES ;
DR   Q4L872, LACC_STAHJ ;  Q3JZ20, LACC_STRA1 ;  Q8DXC2, LACC_STRA5 ;
DR   P26421, LACC_STRMU ;  Q99Y14, LACC_STRP1 ;  Q04KC3, LACC_STRP2 ;
DR   P0DC12, LACC_STRP3 ;  B5E4T0, LACC_STRP4 ;  Q5X9Y3, LACC_STRP6 ;
DR   C1C7G0, LACC_STRP7 ;  Q8NZD9, LACC_STRP8 ;  Q1J9U8, LACC_STRPB ;
DR   Q1JJZ7, LACC_STRPC ;  Q1JEY9, LACC_STRPD ;  Q1J4Q3, LACC_STRPF ;
DR   A2RGF2, LACC_STRPG ;  B1IBZ5, LACC_STRPI ;  B8ZQ64, LACC_STRPJ ;
DR   Q48RC4, LACC_STRPM ;  Q97QL2, LACC_STRPN ;  P0DC13, LACC_STRPQ ;
DR   B2IPT7, LACC_STRPS ;  B5XII4, LACC_STRPZ ;  Q8DPP1, LACC_STRR6 ;
DR   A3CPH5, LACC_STRSV ;  B9DU93, LACC_STRU0 ;  C1CEF2, LACC_STRZJ ;
DR   C1CKT7, LACC_STRZP ;  C1CRA6, LACC_STRZT ;
//
ID   2.7.1.145
DE   Deoxynucleoside kinase.
AN   Ms-dNK.
AN   Multifunctional deoxynucleoside kinase.
AN   Multispecific deoxynucleoside kinase.
AN   Multisubstrate deoxyribonucleoside kinase.
CA   ATP + 2'-deoxynucleoside = ADP + 2'-deoxynucleoside 5'-phosphate.
CC   -!- The enzyme from embryonic cells of Drosophila melanogaster differs
CC       from other deoxynucleoside kinases (EC 2.7.1.76 and EC 2.7.1.113) in
CC       its broad specificity for all four common deoxynucleosides.
DR   Q9XZT6, DNK_DROME  ;
//
ID   2.7.1.146
DE   ADP-specific phosphofructokinase.
AN   ADP-6-phosphofructokinase.
AN   ADP-dependent phosphofructokinase.
AN   ADP-Pfk.
CA   ADP + D-fructose 6-phosphate = AMP + D-fructose 1,6-bisphosphate.
CF   Magnesium or cobalt.
CC   -!- ADP can be replaced by GDP, ATP and GTP, to a limited extent.
DR   P58847, K6PF_METAC ;  Q58999, K6PF_METJA ;  Q9V1A6, K6PF_PYRAB ;
DR   Q9V2Z7, K6PF_PYRFU ;  O59355, K6PF_PYRHO ;  Q5JD05, K6PF_PYRKO ;
DR   Q977Q3, K6PF_THELI ;  Q9HH12, K6PF_THEZI ;
//
ID   2.7.1.147
DE   ADP-specific glucokinase.
AN   ADP-dependent glucokinase.
CA   ADP + D-glucose = AMP + D-glucose 6-phosphate.
CF   Magnesium.
CC   -!- The enzyme from Pyrococcus furiosus is highly specific for D-glucose;
CC       there is some activity with 2-deoxy-D-glucose, but no activity with
CC       D-fructose, D-mannose or D-galactose as the substrate.
CC   -!- No activity is detected when ADP is replaced by ATP, GDP,
CC       phosphoenolpyruvate, diphosphate or polyphosphate.
DR   A2VE47, ADPGK_BOVIN;  Q86S40, ADPGK_CAEEL;  Q9BRR6, ADPGK_HUMAN;
DR   Q8VDL4, ADPGK_MOUSE;  Q9UYQ3, GLKA_PYRAB ;  Q9V2Z6, GLKA_PYRFU ;
DR   O58328, GLKA_PYRHO ;  Q5JE39, GLKA_PYRKO ;  Q7M537, GLKA_THELI ;
DR   C6A124, GLKA_THESM ;  Q58999, K6PF_METJA ;
//
ID   2.7.1.148
DE   4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase.
AN   4-diphosphocytidyl-2-C-methyl-D-erythritol kinase.
AN   CDP-ME kinase.
AN   CMK.
CA   ATP + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = ADP +
CA   2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol.
CF   Manganese or magnesium.
CC   -!- Forms part of an alternative nonmevalonate pathway for terpenoid
CC       biosynthesis.
DR   B0CC88, ISPE_ACAM1 ;  A1TT72, ISPE_ACIAC ;  Q6F8J0, ISPE_ACIAD ;
DR   B7GYQ7, ISPE_ACIB3 ;  B7I7P3, ISPE_ACIB5 ;  B2HUM5, ISPE_ACIBC ;
DR   A3M2X4, ISPE_ACIBT ;  B9ME49, ISPE_ACIET ;  A1W4G3, ISPE_ACISJ ;
DR   A3N0D8, ISPE_ACTP2 ;  B3H1B7, ISPE_ACTP7 ;  B0BP57, ISPE_ACTPJ ;
DR   A6VQ56, ISPE_ACTSZ ;  A0KN01, ISPE_AERHH ;  A4SK61, ISPE_AERS4 ;
DR   Q8UHP8, ISPE_AGRT5 ;  Q0VS81, ISPE_ALCBS ;  Q0AC00, ISPE_ALHEH ;
DR   B6EHH2, ISPE_ALISL ;  A6TWV7, ISPE_ALKMQ ;  A8ML31, ISPE_ALKOO ;
DR   B8J808, ISPE_ANAD2 ;  Q2IM67, ISPE_ANADE ;  A7H6J9, ISPE_ANADF ;
DR   B9KIB9, ISPE_ANAMF ;  Q5PB05, ISPE_ANAMM ;  Q2GKD6, ISPE_ANAPZ ;
DR   B4ULC6, ISPE_ANASK ;  B9MJX8, ISPE_ANATD ;  Q3M3F2, ISPE_ANAVT ;
DR   O67060, ISPE_AQUAE ;  O81014, ISPE_ARATH ;  Q5P725, ISPE_AROAE ;
DR   A1R4F8, ISPE_ARTAT ;  B8HF09, ISPE_ARTCA ;  A0JU88, ISPE_ARTS2 ;
DR   A8HU60, ISPE_AZOC5 ;  B6YQC6, ISPE_AZOPC ;  A1K3G8, ISPE_AZOSB ;
DR   A7Z0G9, ISPE_BACA2 ;  C3P9J0, ISPE_BACAA ;  C3LJ17, ISPE_BACAC ;
DR   A0R8B7, ISPE_BACAH ;  Q81VZ6, ISPE_BACAN ;  B7JK51, ISPE_BACC0 ;
DR   Q73FG3, ISPE_BACC1 ;  B7ISV5, ISPE_BACC2 ;  C1ESX4, ISPE_BACC3 ;
DR   B7HIL3, ISPE_BACC4 ;  B7HPV6, ISPE_BACC7 ;  A7GJV7, ISPE_BACCN ;
DR   B9IZC8, ISPE_BACCQ ;  Q81JA2, ISPE_BACCR ;  Q63HI8, ISPE_BACCZ ;
DR   Q5LC56, ISPE_BACFN ;  Q64T40, ISPE_BACFR ;  Q9KGK0, ISPE_BACHD ;
DR   Q6HPX2, ISPE_BACHK ;  Q65PH5, ISPE_BACLD ;  A8F913, ISPE_BACP2 ;
DR   Q5WLV8, ISPE_BACSK ;  P37550, ISPE_BACSU ;  Q8AA41, ISPE_BACTN ;
DR   A6L5X6, ISPE_BACV8 ;  A9VN58, ISPE_BACWK ;  A1URV3, ISPE_BARBK ;
DR   Q6G4E4, ISPE_BARHE ;  Q6G0G3, ISPE_BARQU ;  A9IQK8, ISPE_BART1 ;
DR   Q1LTH3, ISPE_BAUCH ;  A1A3W4, ISPE_BIFAA ;  B3DP37, ISPE_BIFLD ;
DR   Q8G6I4, ISPE_BIFLO ;  B7GPE4, ISPE_BIFLS ;  Q492W0, ISPE_BLOPB ;
DR   Q7WNY5, ISPE_BORBR ;  Q7W182, ISPE_BORPA ;  Q7VUH0, ISPE_BORPE ;
DR   Q89S79, ISPE_BRAJA ;  A5EEC6, ISPE_BRASB ;  A4YPQ3, ISPE_BRASO ;
DR   C0ZHC9, ISPE_BREBN ;  Q2YMB5, ISPE_BRUA2 ;  Q57EW9, ISPE_BRUAB ;
DR   Q8YFI3, ISPE_BRUME ;  Q8G2D0, ISPE_BRUSU ;  P57267, ISPE_BUCAI ;
DR   Q8K9X1, ISPE_BUCAP ;  B1YN51, ISPE_BURA4 ;  Q1BTG7, ISPE_BURCA ;
DR   B1JYP8, ISPE_BURCC ;  A0KAM4, ISPE_BURCH ;  B4EAR4, ISPE_BURCJ ;
DR   Q0BBQ6, ISPE_BURCM ;  A9AEY9, ISPE_BURM1 ;  A3MQB6, ISPE_BURM7 ;
DR   A2S6B7, ISPE_BURM9 ;  Q62FC4, ISPE_BURMA ;  A1UZN5, ISPE_BURMS ;
DR   A3NR98, ISPE_BURP0 ;  Q3JW85, ISPE_BURP1 ;  A3N5K2, ISPE_BURP6 ;
DR   B2JCP0, ISPE_BURP8 ;  B2SXG6, ISPE_BURPP ;  Q63XL7, ISPE_BURPS ;
DR   Q39CU1, ISPE_BURS3 ;  Q2T1B6, ISPE_BURTA ;  A4JHZ4, ISPE_BURVG ;
DR   Q145X1, ISPE_BURXL ;  A4XLL8, ISPE_CALS8 ;  A8FMF7, ISPE_CAMJ8 ;
DR   A7H2Q3, ISPE_CAMJD ;  Q9PNJ0, ISPE_CAMJE ;  A1W091, ISPE_CAMJJ ;
DR   Q5HU00, ISPE_CAMJR ;  Q3AFM4, ISPE_CARHZ ;  B8H510, ISPE_CAUCN ;
DR   Q9A8L7, ISPE_CAUCR ;  B0T7V9, ISPE_CAUSK ;  B3PJN8, ISPE_CELJU ;
DR   Q5L568, ISPE_CHLAB ;  Q3AQY2, ISPE_CHLCH ;  Q821X0, ISPE_CHLCV ;
DR   Q255R7, ISPE_CHLFF ;  B3EE40, ISPE_CHLL2 ;  Q9PLC0, ISPE_CHLMU ;
DR   B3QPX7, ISPE_CHLP8 ;  B3EP19, ISPE_CHLPB ;  A1BHM3, ISPE_CHLPD ;
DR   B0B931, ISPE_CHLT2 ;  B3QW77, ISPE_CHLT3 ;  Q3KKN7, ISPE_CHLTA ;
DR   B0BAR0, ISPE_CHLTB ;  Q8KCC7, ISPE_CHLTE ;  O84810, ISPE_CHLTR ;
DR   Q1QXD0, ISPE_CHRSD ;  Q7NQS8, ISPE_CHRVO ;  A8AFZ9, ISPE_CITK8 ;
DR   A5CTL3, ISPE_CLAM3 ;  B0RGI6, ISPE_CLAMS ;  Q97F51, ISPE_CLOAB ;
DR   A7FQF0, ISPE_CLOB1 ;  C3KYF7, ISPE_CLOB6 ;  A6LQF2, ISPE_CLOB8 ;
DR   B2UZH3, ISPE_CLOBA ;  B2TJM0, ISPE_CLOBB ;  A5HY17, ISPE_CLOBH ;
DR   C1FQ79, ISPE_CLOBJ ;  B1IE03, ISPE_CLOBK ;  A7G9M4, ISPE_CLOBL ;
DR   B1KSP3, ISPE_CLOBM ;  Q181G8, ISPE_CLOD6 ;  B9DX96, ISPE_CLOK1 ;
DR   A5N3L3, ISPE_CLOK5 ;  A0Q330, ISPE_CLONN ;  Q0TNA0, ISPE_CLOP1 ;
DR   Q8XIA9, ISPE_CLOPE ;  A9KKE9, ISPE_CLOPH ;  Q0SQX1, ISPE_CLOPS ;
DR   Q899A2, ISPE_CLOTE ;  A3DI26, ISPE_CLOTH ;  Q47Y90, ISPE_COLP3 ;
DR   Q6NIA1, ISPE_CORDI ;  Q8FQZ4, ISPE_COREF ;  A4QCP1, ISPE_CORGB ;
DR   Q8NRY0, ISPE_CORGL ;  Q4JU24, ISPE_CORJK ;  Q0KEP7, ISPE_CUPNH ;
DR   Q476F8, ISPE_CUPPJ ;  B2AGT9, ISPE_CUPTR ;  B8HU41, ISPE_CYAP4 ;
DR   B7K961, ISPE_CYAP7 ;  Q11VT3, ISPE_CYTH3 ;  Q479M3, ISPE_DECAR ;
DR   Q3Z9E9, ISPE_DEHE1 ;  A5FS53, ISPE_DEHSB ;  Q3ZZE5, ISPE_DEHSC ;
DR   Q1J201, ISPE_DEIGD ;  Q9RR89, ISPE_DEIRA ;  A9BP16, ISPE_DELAS ;
DR   Q30ZH4, ISPE_DESDG ;  B8FY51, ISPE_DESHD ;  Q251V5, ISPE_DESHY ;
DR   C4XHQ9, ISPE_DESMR ;  Q6AJL6, ISPE_DESPS ;  A4J0P1, ISPE_DESRM ;
DR   Q72BQ8, ISPE_DESVH ;  A1VDQ8, ISPE_DESVV ;  A8LL57, ISPE_DINSH ;
DR   A7ZKY2, ISPE_ECO24 ;  B7UQ96, ISPE_ECO27 ;  B7MKB0, ISPE_ECO45 ;
DR   B7LGW9, ISPE_ECO55 ;  P62616, ISPE_ECO57 ;  B5YXM6, ISPE_ECO5E ;
DR   B7NUX4, ISPE_ECO7I ;  B7MTZ2, ISPE_ECO81 ;  B7LXC3, ISPE_ECO8A ;
DR   C4ZTP9, ISPE_ECOBW ;  B1XAP9, ISPE_ECODH ;  A7ZZE4, ISPE_ECOHS ;
DR   A1AAD5, ISPE_ECOK1 ;  Q0TIG2, ISPE_ECOL5 ;  Q8FI04, ISPE_ECOL6 ;
DR   B1IU85, ISPE_ECOLC ;  P62615, ISPE_ECOLI ;  B7N419, ISPE_ECOLU ;
DR   B6I9S3, ISPE_ECOSE ;  B1LH92, ISPE_ECOSM ;  Q1RCN0, ISPE_ECOUT ;
DR   Q3YSE4, ISPE_EHRCJ ;  Q2GG78, ISPE_EHRCR ;  Q5FHM5, ISPE_EHRRG ;
DR   Q5HBJ6, ISPE_EHRRW ;  A4WBC9, ISPE_ENT38 ;  Q839U9, ISPE_ENTFA ;
DR   A7MKB5, ISPE_ENTS8 ;  Q6D554, ISPE_ERWCT ;  B2VEI4, ISPE_ERWT9 ;
DR   Q2NA15, ISPE_ERYLH ;  B7LSI2, ISPE_ESCF3 ;  C4Z205, ISPE_EUBE2 ;
DR   B1YGP2, ISPE_EXIS2 ;  A7HNL5, ISPE_FERNB ;  B0S057, ISPE_FINM2 ;
DR   B0TVZ0, ISPE_FRAP2 ;  Q14JH1, ISPE_FRAT1 ;  A7N9I8, ISPE_FRATF ;
DR   Q2A5Q2, ISPE_FRATH ;  B2SE44, ISPE_FRATM ;  A0Q492, ISPE_FRATN ;
DR   Q0BP04, ISPE_FRATO ;  Q5NI19, ISPE_FRATT ;  A4IZZ4, ISPE_FRATW ;
DR   Q8R6C8, ISPE_FUSNN ;  B5EHY0, ISPE_GEOBB ;  Q5L3V4, ISPE_GEOKA ;
DR   Q39RQ7, ISPE_GEOMG ;  B9M5U2, ISPE_GEOSF ;  Q74FE9, ISPE_GEOSL ;
DR   C6E4K5, ISPE_GEOSM ;  C5D367, ISPE_GEOSW ;  A4IJC2, ISPE_GEOTN ;
DR   A5G7R8, ISPE_GEOUR ;  Q7NPF3, ISPE_GLOVI ;  A9HAC0, ISPE_GLUDA ;
DR   Q5FQP6, ISPE_GLUOX ;  Q0BR06, ISPE_GRABC ;  Q7VL54, ISPE_HAEDU ;
DR   Q4QL43, ISPE_HAEI8 ;  P45271, ISPE_HAEIN ;  Q0I368, ISPE_HAES1 ;
DR   B0UUJ6, ISPE_HAES2 ;  Q2SLA0, ISPE_HAHCH ;  A1WVQ4, ISPE_HALHL ;
DR   C4K7Z0, ISPE_HAMD5 ;  Q17Z99, ISPE_HELAH ;  B0TB90, ISPE_HELMI ;
DR   Q1CRI6, ISPE_HELPH ;  Q9ZJH3, ISPE_HELPJ ;  O25984, ISPE_HELPY ;
DR   A4G919, ISPE_HERAR ;  B4U5Q9, ISPE_HYDS0 ;  Q0C4D8, ISPE_HYPNA ;
DR   Q5QV06, ISPE_IDILO ;  A6T2S0, ISPE_JANMA ;  Q28V59, ISPE_JANSC ;
DR   A6W6U5, ISPE_KINRD ;  B5XW48, ISPE_KLEP3 ;  A6TAP2, ISPE_KLEP7 ;
DR   Q03T54, ISPE_LACBA ;  B2GFD7, ISPE_LACF3 ;  Q88Z91, ISPE_LACPL ;
DR   A5VI11, ISPE_LACRD ;  B2G5J0, ISPE_LACRJ ;  Q1WV68, ISPE_LACS1 ;
DR   Q38V25, ISPE_LACSS ;  Q1MQD8, ISPE_LAWIP ;  Q6ADP2, ISPE_LEIXX ;
DR   B0SA95, ISPE_LEPBA ;  B0SKG9, ISPE_LEPBP ;  Q72V75, ISPE_LEPIC ;
DR   Q8EZM8, ISPE_LEPIN ;  Q92F77, ISPE_LISIN ;  C1KYC3, ISPE_LISMC ;
DR   Q724M3, ISPE_LISMF ;  B8DGN5, ISPE_LISMH ;  Q8YAE1, ISPE_LISMO ;
DR   A0AEZ5, ISPE_LISW6 ;  B9E8V7, ISPE_MACCJ ;  Q2VYT6, ISPE_MAGSA ;
DR   A0L5U5, ISPE_MAGSM ;  Q65SB8, ISPE_MANSM ;  A1U371, ISPE_MARAV ;
DR   A6W1C6, ISPE_MARMS ;  P56848, ISPE_MENPI ;  Q11KG9, ISPE_MESSB ;
DR   B7KUL9, ISPE_METC4 ;  Q60A17, ISPE_METCA ;  A9VX42, ISPE_METEP ;
DR   Q1H3J0, ISPE_METFK ;  B3DVI7, ISPE_METI4 ;  B1ZIP6, ISPE_METPB ;
DR   A2SKU4, ISPE_METPP ;  B1LYB4, ISPE_METRJ ;  B0JNB0, ISPE_MICAN ;
DR   Q2RMC8, ISPE_MOOTA ;  A0QBW1, ISPE_MYCA1 ;  P65179, ISPE_MYCBO ;
DR   A1KHE9, ISPE_MYCBP ;  C1AM02, ISPE_MYCBT ;  A4T6N7, ISPE_MYCGI ;
DR   B8ZU60, ISPE_MYCLB ;  Q9CD51, ISPE_MYCLE ;  B2HDJ9, ISPE_MYCMM ;
DR   Q741W1, ISPE_MYCPA ;  A0R3D7, ISPE_MYCS2 ;  A5U154, ISPE_MYCTA ;
DR   P65178, ISPE_MYCTU ;  A0PW69, ISPE_MYCUA ;  A1TEH2, ISPE_MYCVP ;
DR   Q5F9F6, ISPE_NEIG1 ;  B4RKF0, ISPE_NEIG2 ;  A9M421, ISPE_NEIM0 ;
DR   Q9JUX8, ISPE_NEIMA ;  Q9JZW4, ISPE_NEIMB ;  A1KTB5, ISPE_NEIMF ;
DR   Q2GD50, ISPE_NEOSM ;  Q0AGY8, ISPE_NITEC ;  Q82TQ3, ISPE_NITEU ;
DR   Q1QIJ6, ISPE_NITHX ;  Q2YBH5, ISPE_NITMU ;  Q3JDR0, ISPE_NITOC ;
DR   Q3SPE5, ISPE_NITWN ;  Q5YPY8, ISPE_NOCFA ;  A1SNG8, ISPE_NOCSJ ;
DR   B2J0A5, ISPE_NOSP7 ;  Q8YS61, ISPE_NOSS1 ;  Q2G7F1, ISPE_NOVAD ;
DR   Q8EU37, ISPE_OCEIH ;  A6L9X1, ISPE_PARD8 ;  A1AZ43, ISPE_PARDP ;
DR   A7HR11, ISPE_PARL1 ;  Q6MAT6, ISPE_PARUW ;  P57833, ISPE_PASMU ;
DR   C6DHY4, ISPE_PECCP ;  Q03HF4, ISPE_PEDPA ;  Q3A311, ISPE_PELCD ;
DR   Q3B2S6, ISPE_PELLD ;  B4SG33, ISPE_PELPB ;  A1ALZ9, ISPE_PELPD ;
DR   A5D654, ISPE_PELTS ;  Q4FPG0, ISPE_PELUB ;  C0QQW3, ISPE_PERMH ;
DR   A9BFC2, ISPE_PETMO ;  Q7N589, ISPE_PHOLL ;  Q6LNB1, ISPE_PHOPR ;
DR   A1VKN9, ISPE_POLNA ;  B1XS63, ISPE_POLNS ;  Q12DZ8, ISPE_POLSJ ;
DR   A4T067, ISPE_POLSQ ;  B2RJI6, ISPE_PORG3 ;  Q7MVU8, ISPE_PORGI ;
DR   B4S9D9, ISPE_PROA2 ;  Q6AAD6, ISPE_PROAC ;  A3PCS4, ISPE_PROM0 ;
DR   A2C1Z6, ISPE_PROM1 ;  A8G4P2, ISPE_PROM2 ;  A2CA52, ISPE_PROM3 ;
DR   A2BWR1, ISPE_PROM5 ;  Q31B18, ISPE_PROM9 ;  Q7VCH6, ISPE_PROMA ;
DR   B4EVR4, ISPE_PROMH ;  Q7V7W1, ISPE_PROMM ;  Q7V1E2, ISPE_PROMP ;
DR   A2BR01, ISPE_PROMS ;  Q46L57, ISPE_PROMT ;  A4SFS4, ISPE_PROVI ;
DR   Q48MV8, ISPE_PSE14 ;  Q15SQ6, ISPE_PSEA6 ;  A6VC65, ISPE_PSEA7 ;
DR   B7V0L5, ISPE_PSEA8 ;  Q02G05, ISPE_PSEAB ;  P42805, ISPE_PSEAE ;
DR   Q1IEY5, ISPE_PSEE4 ;  Q4K691, ISPE_PSEF5 ;  C3KDC2, ISPE_PSEFS ;
DR   Q3IK98, ISPE_PSEHT ;  A4XR57, ISPE_PSEMY ;  A5VYG1, ISPE_PSEP1 ;
DR   Q3K6W5, ISPE_PSEPF ;  B0KND7, ISPE_PSEPG ;  Q88PX5, ISPE_PSEPK ;
DR   B1JEQ0, ISPE_PSEPW ;  Q888C5, ISPE_PSESM ;  Q4ZXX1, ISPE_PSEU2 ;
DR   A4VPC3, ISPE_PSEU5 ;  Q4FVB2, ISPE_PSYA2 ;  Q1QED3, ISPE_PSYCK ;
DR   A1STD9, ISPE_PSYIN ;  A5WHA3, ISPE_PSYWF ;  Q1LRQ0, ISPE_RALME ;
DR   B2UER7, ISPE_RALPJ ;  Q8Y2E0, ISPE_RALSO ;  B3PRG5, ISPE_RHIE6 ;
DR   Q2KBV2, ISPE_RHIEC ;  Q1MKS2, ISPE_RHIL3 ;  Q986C6, ISPE_RHILO ;
DR   B5ZS25, ISPE_RHILW ;  Q92RM1, ISPE_RHIME ;  Q7UEV3, ISPE_RHOBA ;
DR   Q21XW4, ISPE_RHOFD ;  Q2J164, ISPE_RHOP2 ;  Q07I91, ISPE_RHOP5 ;
DR   Q6NAZ1, ISPE_RHOPA ;  Q20YA7, ISPE_RHOPB ;  Q13BT8, ISPE_RHOPS ;
DR   Q2RXS7, ISPE_RHORT ;  A3PGS6, ISPE_RHOS1 ;  Q3J5K7, ISPE_RHOS4 ;
DR   A4WVE5, ISPE_RHOS5 ;  B9KLF9, ISPE_RHOSK ;  Q0S4S3, ISPE_RHOSR ;
DR   Q163E9, ISPE_ROSDO ;  Q1AXL8, ISPE_RUBXD ;  A1AVE9, ISPE_RUTMC ;
DR   Q21FL9, ISPE_SACD2 ;  A4F7X3, ISPE_SACEN ;  B5F4H2, ISPE_SALA4 ;
DR   A8M223, ISPE_SALAI ;  A9MP98, ISPE_SALAR ;  Q57NN2, ISPE_SALCH ;
DR   B5R3J6, ISPE_SALEP ;  B5R921, ISPE_SALG2 ;  B4TKA8, ISPE_SALHS ;
DR   Q5PCR2, ISPE_SALPA ;  A9MW00, ISPE_SALPB ;  C0Q357, ISPE_SALPC ;
DR   B5BI72, ISPE_SALPK ;  Q2S4Q4, ISPE_SALRD ;  B4TXU6, ISPE_SALSV ;
DR   Q8Z699, ISPE_SALTI ;  A4X310, ISPE_SALTO ;  P30753, ISPE_SALTY ;
DR   A8GDA0, ISPE_SERP5 ;  A1S8R5, ISPE_SHEAM ;  B8E818, ISPE_SHEB2 ;
DR   A3D0F8, ISPE_SHEB5 ;  A6WSF3, ISPE_SHEB8 ;  A9L2D7, ISPE_SHEB9 ;
DR   Q12QS1, ISPE_SHEDO ;  Q087I7, ISPE_SHEFN ;  B0TR30, ISPE_SHEHH ;
DR   A3QH33, ISPE_SHELP ;  Q8EAR0, ISPE_SHEON ;  A8H7A8, ISPE_SHEPA ;
DR   A4Y3J5, ISPE_SHEPC ;  B8CQV5, ISPE_SHEPW ;  A0KT85, ISPE_SHESA ;
DR   A8FYZ3, ISPE_SHESH ;  Q0HFC5, ISPE_SHESM ;  Q0HYL1, ISPE_SHESR ;
DR   A1RNE4, ISPE_SHESW ;  B1KDU6, ISPE_SHEWM ;  B2TZV6, ISPE_SHIB3 ;
DR   Q31ZQ1, ISPE_SHIBS ;  Q32GZ9, ISPE_SHIDS ;  Q0T5I7, ISPE_SHIF8 ;
DR   Q83LD8, ISPE_SHIFL ;  Q3Z0S6, ISPE_SHISS ;  Q5LX98, ISPE_SILPO ;
DR   A6U6N3, ISPE_SINMW ;  Q2NRS1, ISPE_SODGM ;  P93841, ISPE_SOLLC ;
DR   Q01QR0, ISPE_SOLUE ;  Q1GTW9, ISPE_SPHAL ;  A5VDT3, ISPE_SPHWW ;
DR   A7WYP4, ISPE_STAA1 ;  A6TYW9, ISPE_STAA2 ;  Q2FJE7, ISPE_STAA3 ;
DR   Q2G0S8, ISPE_STAA8 ;  A5IQ47, ISPE_STAA9 ;  Q2YVV0, ISPE_STAAB ;
DR   Q5HII1, ISPE_STAAC ;  A6QEE8, ISPE_STAAE ;  P65180, ISPE_STAAM ;
DR   P65181, ISPE_STAAN ;  Q6GJH6, ISPE_STAAR ;  Q6GBZ3, ISPE_STAAS ;
DR   P65182, ISPE_STAAW ;  Q5HRR0, ISPE_STAEQ ;  Q8CQU6, ISPE_STAES ;
DR   Q4L3F2, ISPE_STAHJ ;  Q49V04, ISPE_STAS1 ;  Q3K3L9, ISPE_STRA1 ;
DR   Q8E7K5, ISPE_STRA3 ;  Q8E245, ISPE_STRA5 ;  Q820G3, ISPE_STRAW ;
DR   Q9K3R6, ISPE_STRCO ;  C0MBI2, ISPE_STRE4 ;  B4U041, ISPE_STREM ;
DR   Q8DS40, ISPE_STRMU ;  C0MED6, ISPE_STRS7 ;  B9DSY9, ISPE_STRU0 ;
DR   Q30TG0, ISPE_SULDN ;  A6Q782, ISPE_SULNB ;  B2V7G0, ISPE_SULSY ;
DR   Q67JC2, ISPE_SYMTH ;  Q2LUJ9, ISPE_SYNAS ;  Q31RH7, ISPE_SYNE7 ;
DR   A0LPG9, ISPE_SYNFM ;  Q2JQU4, ISPE_SYNJA ;  Q2JLP6, ISPE_SYNJB ;
DR   B1XK39, ISPE_SYNP2 ;  Q5N2S7, ISPE_SYNP6 ;  A5GLH6, ISPE_SYNPW ;
DR   Q7U7D2, ISPE_SYNPX ;  A5GTK8, ISPE_SYNR3 ;  Q0I9S4, ISPE_SYNS3 ;
DR   Q3AXF4, ISPE_SYNS9 ;  Q3AKD9, ISPE_SYNSC ;  Q0B0T2, ISPE_SYNWW ;
DR   P72663, ISPE_SYNY3 ;  B7IG15, ISPE_THEAB ;  Q8DLJ1, ISPE_THEEB ;
DR   Q47SX2, ISPE_THEFY ;  A8F7B1, ISPE_THELT ;  A6LJT9, ISPE_THEM4 ;
DR   Q9X1A3, ISPE_THEMA ;  A5IMJ0, ISPE_THEP1 ;  B0KBH0, ISPE_THEP3 ;
DR   B0K474, ISPE_THEPX ;  B1LBU2, ISPE_THESQ ;  Q72GN2, ISPE_THET2 ;
DR   P83700, ISPE_THET8 ;  Q8R765, ISPE_THETN ;  B5YG57, ISPE_THEYD ;
DR   Q3SLR6, ISPE_THIDA ;  C4LBL2, ISPE_TOLAT ;  Q73N18, ISPE_TREDE ;
DR   O83386, ISPE_TREPA ;  B2S2W8, ISPE_TREPS ;  Q10VR1, ISPE_TRIEI ;
DR   Q83IA0, ISPE_TROW8 ;  Q83FU3, ISPE_TROWT ;  B1AJP1, ISPE_UREP2 ;
DR   Q9PPN9, ISPE_UREPA ;  B5ZCB5, ISPE_UREU1 ;  C5CYZ4, ISPE_VARPS ;
DR   A1WGH3, ISPE_VEREI ;  A5CXR1, ISPE_VESOH ;  A5F684, ISPE_VIBC3 ;
DR   Q9KQ23, ISPE_VIBCH ;  C3LPI7, ISPE_VIBCM ;  Q5E6T6, ISPE_VIBF1 ;
DR   B5FBW7, ISPE_VIBFM ;  A7MY79, ISPE_VIBHB ;  Q87RN7, ISPE_VIBPA ;
DR   B7VKH0, ISPE_VIBSL ;  Q8DFF6, ISPE_VIBVU ;  Q7MMZ0, ISPE_VIBVY ;
DR   Q8D2K6, ISPE_WIGBR ;  Q73I23, ISPE_WOLPM ;  Q5GTB0, ISPE_WOLTR ;
DR   C0R2S8, ISPE_WOLWR ;  Q8PNU1, ISPE_XANAC ;  Q3BX03, ISPE_XANC5 ;
DR   Q4URC0, ISPE_XANC8 ;  B0RUA1, ISPE_XANCB ;  Q8PC64, ISPE_XANCP ;
DR   Q2NZW6, ISPE_XANOM ;  Q5GWR3, ISPE_XANOR ;  A7IF36, ISPE_XANP2 ;
DR   Q9PA75, ISPE_XYLFA ;  Q87A21, ISPE_XYLFT ;  A7FIG4, ISPE_YERP3 ;
DR   Q1C857, ISPE_YERPA ;  B2K2Y7, ISPE_YERPB ;  Q8ZEY1, ISPE_YERPE ;
DR   A9QZ11, ISPE_YERPG ;  Q1CJK4, ISPE_YERPN ;  A4TJP0, ISPE_YERPP ;
DR   Q66AX8, ISPE_YERPS ;  B1JM88, ISPE_YERPY ;  Q9X3W5, ISPE_ZYMMO ;
//
ID   2.7.1.149
DE   1-phosphatidylinositol-5-phosphate 4-kinase.
AN   Type II PIP kinase.
CA   ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-
CA   1D-myo-inositol 4,5-bisphosphate.
DR   Q5F356, PI42A_CHICK;  P48426, PI42A_HUMAN;  O70172, PI42A_MOUSE;
DR   O13010, PI42A_PIG  ;  Q9R0I8, PI42A_RAT  ;  P78356, PI42B_HUMAN;
DR   Q80XI4, PI42B_MOUSE;  O88377, PI42B_RAT  ;  Q0P5F7, PI42C_BOVIN;
DR   Q6IQE1, PI42C_DANRE;  Q8TBX8, PI42C_HUMAN;  Q91XU3, PI42C_MOUSE;
DR   Q5R488, PI42C_PONAB;  O88370, PI42C_RAT  ;  Q5PQ01, PI42C_XENLA;
DR   Q6GL14, PI42C_XENTR;
//
ID   2.7.1.150
DE   1-phosphatidylinositol-3-phosphate 5-kinase.
AN   Phosphatidylinositol 3-phosphate 5-kinase.
AN   Type III PIP kinase.
CA   ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate = ADP + 1-phosphatidyl-
CA   1D-myo-inositol 3,5-bisphosphate.
DR   O59722, FAB1_SCHPO ;  P34756, FAB1_YEAST ;  B0G126, FYV1_DICDI ;
DR   O96838, FYV1_DROME ;  Q9Y2I7, FYV1_HUMAN ;  Q9Z1T6, FYV1_MOUSE ;
//
ID   2.7.1.151
DE   Inositol-polyphosphate multikinase.
AN   Inositol polyphosphate 6-/3-/5-kinase.
AN   IP3/IP4 6-/3-kinase.
AN   IP3/IP4 dual-specificity 6-/3-kinase.
AN   IpK2.
CA   (1) ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol
CA   1,4,5,6-tetrakisphosphate.
CA   (2) ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-
CA   inositol 1,3,4,5,6-pentakisphosphate.
CC   -!- This enzyme also phosphorylates Ins(1,4,5)P(3) to Ins(1,3,4,5)P(4),
CC       Ins(1,3,4,5)P(4) to Ins(1,3,4,5,6)P(5), and Ins(1,3,4,5,6)P(4) to
CC       Ins(PP)P(4), isomer unknown.
CC   -!- The enzyme from the plant Arabidopsis thaliana can also phosphorylate
CC       Ins(1,3,4,6)P(4) and Ins(1,2,3,4,6)P(5) at the D-5-position to
CC       produce 1,3,4,5,6-pentakisphosphate and inositol hexakisphosphate
CC       (InsP(6)), respectively.
CC   -!- Yeast produces InsP(6) from Ins(1,4,5)P(3) by the actions of this
CC       enzyme and EC 2.7.1.158.
DR   Q9LY23, IPMKA_ARATH;  Q9FLT2, IPMKB_ARATH;  Q8NFU5, IPMK_HUMAN ;
DR   Q7TT16, IPMK_MOUSE ;  Q99NI4, IPMK_RAT   ;  P07250, IPMK_YEAST ;
//
ID   2.7.1.152
DE   Transferred entry: 2.7.4.21.
//
ID   2.7.1.153
DE   Phosphatidylinositol-4,5-bisphosphate 3-kinase.
AN   Type I phosphoinositide 3-kinase.
CA   ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = ADP +
CA   1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate.
CC   -!- This enzyme also catalyzes the phosphorylation of PtdIns4P to
CC       PtdIns(3,4)P(2), and of PtdIns to PtdIns3P.
DR   P32871, PK3CA_BOVIN;  P42336, PK3CA_HUMAN;  P42337, PK3CA_MOUSE;
DR   P42338, PK3CB_HUMAN;  Q8BTI9, PK3CB_MOUSE;  Q9Z1L0, PK3CB_RAT  ;
DR   O00329, PK3CD_HUMAN;  O35904, PK3CD_MOUSE;  P48736, PK3CG_HUMAN;
DR   Q9JHG7, PK3CG_MOUSE;  O02697, PK3CG_PIG  ;
//
ID   2.7.1.154
DE   Phosphatidylinositol-4-phosphate 3-kinase.
AN   C2-domain-containing phosphoinositide 3-kinase.
AN   Phosphoinositide 3-kinase.
AN   Type II phosphoinositide 3-kinase.
CA   ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-
CA   1D-myo-inositol 3,4-bisphosphate.
CC   -!- This enzyme also phosphorylates PtdIns to PtdIns3P.
PR   PROSITE; PDOC00710;
DR   O00443, P3C2A_HUMAN;  Q61194, P3C2A_MOUSE;  Q5RAY1, P3C2A_PONAB;
DR   O00750, P3C2B_HUMAN;  O75747, P3C2G_HUMAN;  O70167, P3C2G_MOUSE;
DR   O70173, P3C2G_RAT  ;
//
ID   2.7.1.155
DE   Transferred entry: 2.7.4.24.
//
ID   2.7.1.156
DE   Adenosylcobinamide kinase.
AN   Adenosylcobinamide kinase/adenosylcobinamide-phosphate
AN   guanylyltransferase.
AN   AdoCbi kinase/AdoCbi-phosphate guanylyltransferase.
CA   ATP or GTP + adenosylcobinamide = adenosylcobinamide phosphate +
CA   ADP or GDP.
CC   -!- In Salmonella typhimurium LT2, under anaerobic conditions, CobU
CC       (EC 2.7.7.62 and EC 2.7.1.156), CobT (EC 2.4.2.21),
CC       CobC (EC 3.1.3.73) and CobS (EC 2.7.8.26) catalyze reactions in the
CC       nucleotide loop assembly pathway, which convert adenosylcobinamide
CC       (AdoCbi) into adenosylcobalamin (AdoCbl).
CC   -!- CobT and CobC are involved in 5,6-dimethylbenzimidazole activation
CC       whereby 5,6-dimethylbenzimidazole is converted to its riboside,
CC       alpha-ribazole.
CC   -!- The second branch of the nucleotide loop assembly pathway is the
CC       cobinamide (Cbi) activation branch where AdoCbi or
CC       adenosylcobinamide-phosphate is converted to the activated
CC       intermediate AdoCbi-GDP by CobU.
CC   -!- The final step in adenosylcobalamin biosynthesis is the condensation
CC       of AdoCbi-GDP with alpha-ribazole, which is catalyzed by CobS
CC       (EC 2.7.8.26), to yield adenosylcobalamin.
CC   -!- CobU is a bifunctional enzyme that has both kinase (EC 2.7.1.156) and
CC       guanylyltransferase (EC 2.7.7.62) activities.
CC   -!- However, both activities are not required at all times.
CC   -!- The kinase activity has been proposed to function only when
CC       S.typhimurium is assimilating cobinamide whereas the
CC       guanylyltransferase activity is required for both assimilation of
CC       exogenous cobinamide and for de novo synthesis of adenosylcobalamin.
DR   Q9I466, COBP_PSEAE ;  P29931, COBP_PSEDE ;  P0AE77, COBU_ECO57 ;
DR   P0AE76, COBU_ECOLI ;  Q05599, COBU_SALTY ;
//
ID   2.7.1.157
DE   N-acetylgalactosamine kinase.
AN   GALK2.
AN   GalNAc kinase.
AN   GK2.
AN   N-acetylgalactosamine (GalNAc)-1-phosphate kinase.
CA   ATP + N-acetyl-D-galactosamine = ADP + N-acetyl-alpha-D-galactosamine
CA   1-phosphate.
CF   Magnesium.
CC   -!- The enzyme is highly specific for GalNAc as substrate, but has slight
CC       activity with D-galactose.
PR   PROSITE; PDOC00099;
PR   PROSITE; PDOC00545;
DR   Q01415, GALK2_HUMAN;  Q68FH4, GALK2_MOUSE;  Q5R6J8, GALK2_PONAB;
DR   Q5XIG6, GALK2_RAT  ;
//
ID   2.7.1.158
DE   Inositol-pentakisphosphate 2-kinase.
AN   Inositol 1,3,4,5,6-pentakisphosphate 2-kinase.
AN   Inositol polyphosphate kinase.
AN   Ins(1,3,4,5,6)P(5) 2-kinase.
AN   IP5 2-kinase.
CA   ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + 1D-myo-inositol
CA   hexakisphosphate.
CC   -!- The enzyme can also use Ins(1,4,5,6)P(4) and Ins(1,4,5)P(3) as
CC       substrate.
CC   -!- Inositol hexakisphosphate (phytate) accumulates in storage protein
CC       bodies during seed development and, when hydrolyzed, releases stored
CC       nutrients to the developing seedling before the plant is capable of
CC       absorbing nutrients from its environment.
DR   Q75EW5, IPK1_ASHGO ;  Q59KN8, IPK1_CANAL ;  Q6FRN1, IPK1_CANGA ;
DR   Q6BHL8, IPK1_DEBHA ;  Q6CNG8, IPK1_KLULA ;  Q9USK0, IPK1_SCHPO ;
DR   Q6C6Q7, IPK1_YARLI ;  Q06667, IPK1_YEAST ;  Q93YN9, IPPK_ARATH ;
DR   P0CO35, IPPK_CRYNB ;  P0CO34, IPPK_CRYNJ ;  Q4JL91, IPPK_DANRE ;
DR   Q9W2Q7, IPPK_DROME ;  Q9H8X2, IPPK_HUMAN ;  Q6P1C1, IPPK_MOUSE ;
DR   Q5PXE9, IPPK_RAT   ;  Q4P4C1, IPPK_USTMA ;
//
ID   2.7.1.159
DE   Inositol-1,3,4-trisphosphate 5/6-kinase.
AN   Inositol trisphosphate 5/6-kinase.
AN   Ins(1,3,4)P(3) 5/6-kinase.
AN   IP56K.
CA   (1) ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol
CA   1,3,4,5-tetrakisphosphate.
CA   (2) ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol
CA   1,3,4,6-tetrakisphosphate.
CC   -!- In humans, this enzyme, along with EC 2.7.1.127, EC 2.7.1.140 and
CC       EC 2.7.1.158 is involved in the production of inositol
CC       hexakisphosphate (InsP(6)).
CC   -!- InsP(6) is involved in many cellular processes, including mRNA export
CC       from the nucleus.
CC   -!- Yeast do not have this enzyme, so produce InsP(6) from Ins(1,4,5)P(3)
CC       by the actions of EC 2.7.1.151 and EC 2.7.1.158.
PR   PROSITE; PDOC50975;
DR   Q9SBA5, ITPK1_ARATH;  P0C0T1, ITPK1_BOVIN;  Q5F480, ITPK1_CHICK;
DR   Q7ZU91, ITPK1_DANRE;  Q9XYQ1, ITPK1_ENTHI;  Q13572, ITPK1_HUMAN;
DR   Q84Y01, ITPK1_MAIZE;  Q8BYN3, ITPK1_MOUSE;  Q7SY78, ITPK1_XENLA;
DR   Q9SUG3, ITPK2_ARATH;  O81893, ITPK3_ARATH;  O80568, ITPK4_ARATH;
//
ID   2.7.1.160
DE   2'-phosphotransferase.
AN   Tpt1p.
AN   Yeast 2'-phosphotransferase.
CA   2'-phospho-[ligated tRNA] + NAD(+) = mature tRNA + ADP ribose
CA   1'',2''-phosphate + nicotinamide + H(2)O.
CC   -!- Catalyzes the final step of tRNA splicing in the yeast Saccharomyces
CC       cerevisiae.
CC   -!- The reaction takes place in two steps: in the first step,
CC       the 2'-phosphate on the RNA substrate is ADP-ribosylated, causing the
CC       relase of nicotinamide and the formation of the reaction
CC       intermediate, ADP-ribosylated tRNA.
CC   -!- In the second step, dephosphorylated (mature) tRNA is formed along
CC       with ADP ribose 1'',2''-cyclic phosphate.
CC   -!- Highly specific for oligonucleotide substrates bearing an internal
CC       2'-phosphate.
CC   -!- Oligonucleotides with only a terminal 5'- or 3'-phosphate are not
CC       substrates.
DR   O14045, TPT1_SCHPO ;  Q12272, TPT1_YEAST ;  Q3ZBM7, TRPT1_BOVIN;
DR   Q5EAR5, TRPT1_DANRE;  Q86TN4, TRPT1_HUMAN;  Q8K3A2, TRPT1_MOUSE;
//
ID   2.7.1.161
DE   CTP-dependent riboflavin kinase.
CA   CTP + riboflavin = CDP + FMN.
CC   -!- This archaeal enzyme differs from EC 2.7.1.26 in using CTP as the
CC       donor nucleotide.
CC   -!- UTP, but not ATP or GTP, can also act as a phosphate donor but it is
CC       at least an order of magnitude less efficient than CTP.
CC   -!- Formerly EC 2.7.1.n2.
DR   Q9YA27, RIFK_AERPE ;  O28174, RIFK_ARCFU ;  A8ME45, RIFK_CALMQ ;
DR   A0RTV6, RIFK_CENSY ;  Q5UY62, RIFK_HALMA ;  Q9HNF4, RIFK_HALSA ;
DR   Q18FC4, RIFK_HALWD ;  A2BK57, RIFK_HYPBU ;  A8A9X7, RIFK_IGNH4 ;
DR   A6UVI4, RIFK_META3 ;  Q8TT90, RIFK_METAC ;  A7I4M1, RIFK_METB6 ;
DR   Q46CB8, RIFK_METBF ;  Q12VB0, RIFK_METBU ;  Q2FPM5, RIFK_METHJ ;
DR   Q60365, RIFK_METJA ;  Q8TVJ1, RIFK_METKA ;  A2STY4, RIFK_METLZ ;
DR   A4G005, RIFK_METM5 ;  A9A8B2, RIFK_METM6 ;  A6VIH3, RIFK_METM7 ;
DR   Q8PW87, RIFK_METMA ;  A3CY32, RIFK_METMJ ;  Q6M0T4, RIFK_METMP ;
DR   A5UMN4, RIFK_METS3 ;  A4YHJ0, RIFK_METS5 ;  Q2NHN9, RIFK_METST ;
DR   O27544, RIFK_METTH ;  A6URG2, RIFK_METVS ;  Q3IUQ3, RIFK_NATPD ;
DR   Q6L0E8, RIFK_PICTO ;  Q9UYX4, RIFK_PYRAB ;  Q8ZVR7, RIFK_PYRAE ;
DR   A4WJ34, RIFK_PYRAR ;  A3MV29, RIFK_PYRCJ ;  Q8U262, RIFK_PYRFU ;
DR   O58393, RIFK_PYRHO ;  A1RT34, RIFK_PYRIL ;  Q5JGN9, RIFK_PYRKO ;
DR   A3DNT5, RIFK_STAMF ;  Q4J963, RIFK_SULAC ;  Q97ZG3, RIFK_SULSO ;
DR   Q971U9, RIFK_SULTO ;  Q9HJA6, RIFK_THEAC ;  A1RWC8, RIFK_THEPD ;
DR   Q97BD7, RIFK_THEVO ;  Q0W6F7, RIFK_UNCMA ;
//
ID   2.7.1.162
DE   N-acetylhexosamine 1-kinase.
AN   N-acetylgalactosamine/N-acetylglucosamine 1-kinase.
CA   ATP + N-acetyl-D-hexosamine = ADP + N-acetyl-alpha-D-hexosamine
CA   1-phosphate.
CF   Magnesium.
CC   -!- Involved in the lacto-N-biose I/galacto-N-biose degradation pathway
CC       in the probiotic bacterium Bifidobacterium longum.
CC   -!- Differs from EC 2.7.1.157 as it can phosphorylate both
CC       N-acetylgalactosamine and N-acetylglucosamine at similar rates.
CC   -!- Also has some activity with N-acetyl-D-mannosamine, D-talose and
CC       D-mannose as substrate.
CC   -!- ATP can be replaced by GTP or ITP but with decreased enzyme activity.
//
ID   2.7.1.163
DE   Hygromycin B 4-O-kinase.
AN   Hygromycin-B kinase.
CA   ATP + hygromycin B = ADP + 4-O-phosphohygromycin B.
CC   -!- Phosphorylates the antibiotic hygromycin B.
CC   -!- Whereas the enzyme from Streptomyces hygroscopicus (EC 2.7.1.119)
CC       catalyzes the formation of 7''-O-phosphohygromycin B, this enzyme,
CC       found in Escherichia coli carrying a plasmid conferring resistance to
CC       hygromycin-B, forms 4-O-phosphohygromycin B.
CC   -!- Formerly EC 2.7.1.n6.
DR   P00557, KHYB_ECOLX ;
//
ID   2.7.1.164
DE   O-phosphoseryl-tRNA(Sec) kinase.
AN   L-seryl-tRNA(Sec) kinase.
AN   PSTK.
CA   ATP + L-seryl-tRNA(Sec) = ADP + O-phospho-L-seryl-tRNA(Sec).
CC   -!- In archaea and eukarya selenocysteine formation is achieved by a two-
CC       step process: O-phosphoseryl-tRNA(Sec) kinase (PSTK) phosphorylates
CC       the endogenous L-seryl-tRNA(Sec) to O-phospho-L-seryl-tRNA(Sec),
CC       and then this misacylated amino acid-tRNA species is converted to
CC       L-selenocysteinyl-tRNA(Sec) by EC 2.9.1.2.
CC   -!- Formerly EC 2.7.1.n3.
DR   Q8IV42, PSTK_HUMAN ;  Q58933, PSTK_METJA ;  Q8TUS5, PSTK_METKA ;
DR   Q6LX62, PSTK_METMP ;  Q8BP74, PSTK_MOUSE ;
//
ID   2.7.1.165
DE   Glycerate 2-kinase.
AN   D-glycerate-2-kinase.
CA   ATP + (R)-glycerate = ADP + 2-phospho-(R)-glycerate.
CF   Divalent cation.
CC   -!- A key enzyme in the nonphosphorylative Entner-Doudoroff pathway in
CC       archaea.
CC   -!- In Hyphomicrobium methylovorum GM2 the enzyme is involved in
CC       formaldehyde assaimilation I (serine pathway).
CC   -!- In Escherichia coli the enzyme is involved in
CC       D-glucarate/D-galactarate degradation.
PR   PROSITE; PDOC00706;
//
ID   2.7.1.166
DE   3-deoxy-D-manno-octulosonic acid kinase.
AN   Kdo kinase.
CA   3-deoxy-alpha-D-manno-oct-2-ulopyranonosyl-(2->6)-2-deoxy-2-(((3R)-3-
CA   hydroxypentadecanoyl)amino)-3-O-((3R)-3-hydroxytetradecanoyl)-4-
CA   O-phosphono-beta-D-glucopyranosyl-(1->6)-2-deoxy-3-O-((3R)-3-
CA   hydroxytetradecanoyl)-2-(((3R)-3-hydroxytetradecanoyl)amino)-1-
CA   O-phosphono-alpha-D-glucopyranose + ATP = 3-deoxy-4-O-phosphono-alpha-D-
CA   manno-oct-2-ulopyranosyl-(2->6)-2-deoxy-2-(((3R)-3-
CA   hydroxypentadecanoyl)amino)-3-O-((3R)-3-hydroxytetradecanoyl)-4-
CA   O-phosphono-beta-D-glucopyranosyl-(1->6)-2-deoxy-3-O-((3R)-3-
CA   hydroxytetradecanoyl)-2-(((3R)-3-hydroxytetradecanoyl)amino)-1-
CA   O-phosphono-alpha-D-glucopyranose + ADP.
CC   -!- The enzyme phosphorylates the 4-OH position of KDO in (KDO)-lipid
CC       IV(A).
//
ID   2.7.1.167
DE   D-glycero-beta-D-manno-heptose-7-phosphate kinase.
AN   D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate
AN   adenylyltransferase.
AN   D-beta-D-heptose 7-phosphotransferase.
AN   D-beta-D-heptose-7-phosphate kinase.
AN   Glycero-manno-heptose 7-phosphate kinase.
AN   Heptose 7-phosphate kinase.
AN   HldE1 heptokinase.
CA   D-glycero-beta-D-manno-heptose 7-phosphate + ATP = D-glycero-beta-D-
CA   manno-heptose 1,7-bisphosphate + ADP.
CC   -!- The bifunctional protein hldE includes D-glycero-beta-D-manno-
CC       heptose-7-phosphate kinase and D-glycero-beta-D-manno-heptose
CC       1-phosphate adenylyltransferase activity (cf. EC 2.7.7.70).
CC   -!- The enzyme is involved in biosynthesis of ADP-L-glycero-beta-D-manno-
CC       heptose, which is utilized for assembly of the lipopolysaccharide
CC       inner core in Gram-negative bacteria.
CC   -!- The enzyme selectively produces D-glycero-beta-D-manno-heptose 1,7-
CC       bisphosphate.
//
ID   2.7.1.168
DE   D-glycero-alpha-D-manno-heptose-7-phosphate kinase.
AN   D-alpha-D-heptose-7-phosphate kinase.
CA   D-glycero-alpha-D-manno-heptose 7-phosphate + ATP = D-glycero-alpha-D-
CA   manno-heptose 1,7-bisphosphate + ADP.
CC   -!- The enzyme is involved in biosynthesis of GDP-D-glycero-alpha-D-
CC       manno-heptose, which is required for assembly of S-layer glycoprotein
CC       in Gram-positive bacteria.
CC   -!- The enzyme is specific for the alpha-anomer.
//
ID   2.7.1.169
DE   Pantoate kinase.
CA   ATP + (R)-pantoate = ADP + (R)-4-phosphopantoate.
CC   -!- The conversion of (R)-pantoate to (R)-4'-phosphopantothenate is part
CC       of the pathway leading to biosynthesis of 4'-phosphopantetheine,
CC       an essential cofactor of coenzyme A and acyl-carrier protein.
CC   -!- In bacteria and eukaryotes this conversion is performed by
CC       condensation with beta-alanine, followed by phosphorylation
CC       (EC 6.3.2.1 and EC 2.7.1.33, respectively).
CC   -!- In archaea the order of these two steps is reversed,
CC       and phosphorylation precedes condensation with beta-alanine.
DR   Q58379, POK_METJA  ;  Q5JHF1, POK_PYRKO  ;
//
ID   2.7.1.170
DE   Anhydro-N-acetylmuramic acid kinase.
AN   AnhMurNAc kinase.
CA   ATP + 1,6-anhydro-N-acetyl-beta-muramate + H(2)O = ADP + N-acetylmuramate
CA   6-phosphate.
CC   -!- This enzyme, along with EC 4.2.1.126, is required for the utilization
CC       of anhydro-N-acetylmuramic acid in proteobacteria.
CC   -!- The substrate is either imported from the medium or derived from the
CC       bacterium's own cell wall murein during cell wall recycling.
CC   -!- The product N-acetylmuramate 6-phosphate is produced as a 7:1 mixture
CC       of the alpha- and beta-anomers.
CC   -!- Formerly EC 2.7.1.n1.
DR   Q28RF2, ANMK1_JANSC;  Q28KN6, ANMK2_JANSC;  B0CAA5, ANMK_ACAM1 ;
DR   Q6FG11, ANMK_ACIAD ;  A5FWG7, ANMK_ACICJ ;  B7J3S7, ANMK_ACIF2 ;
DR   A3N2I3, ANMK_ACTP2 ;  B3GYL7, ANMK_ACTP7 ;  B0BRC9, ANMK_ACTPJ ;
DR   B9JJK5, ANMK_AGRRK ;  Q8UED3, ANMK_AGRT5 ;  Q3M7P3, ANMK_ANAVT ;
DR   A8IFI2, ANMK_AZOC5 ;  C3PA65, ANMK_BACAA ;  C3LIG8, ANMK_BACAC ;
DR   A0RE53, ANMK_BACAH ;  Q81QG0, ANMK_BACAN ;  B7JNT4, ANMK_BACC0 ;
DR   Q737Z7, ANMK_BACC1 ;  B7IX20, ANMK_BACC2 ;  C1EUL0, ANMK_BACC3 ;
DR   B7H7M2, ANMK_BACC4 ;  B7HRD6, ANMK_BACC7 ;  B9J0X9, ANMK_BACCQ ;
DR   Q81DH0, ANMK_BACCR ;  Q63BB2, ANMK_BACCZ ;  Q6HIP4, ANMK_BACHK ;
DR   A9VFV1, ANMK_BACWK ;  C5BV64, ANMK_BEUC1 ;  Q2KV10, ANMK_BORA1 ;
DR   Q7WFC8, ANMK_BORBR ;  Q7W3Z6, ANMK_BORPA ;  A9I280, ANMK_BORPD ;
DR   Q7VUW3, ANMK_BORPE ;  Q89M62, ANMK_BRAJA ;  Q2YNQ9, ANMK_BRUA2 ;
DR   Q57DI4, ANMK_BRUAB ;  A9MAU6, ANMK_BRUC2 ;  Q8YGV9, ANMK_BRUME ;
DR   Q8G104, ANMK_BRUSU ;  B1YTD4, ANMK_BURA4 ;  Q1BZ42, ANMK_BURCA ;
DR   B1JVU7, ANMK_BURCC ;  A0K4K8, ANMK_BURCH ;  B4EET3, ANMK_BURCJ ;
DR   Q0BI88, ANMK_BURCM ;  A2S587, ANMK_BURM9 ;  Q62HB5, ANMK_BURMA ;
DR   A3NZ74, ANMK_BURP0 ;  Q3JNR7, ANMK_BURP1 ;  Q63QW9, ANMK_BURPS ;
DR   Q39JJ7, ANMK_BURS3 ;  Q2SZ63, ANMK_BURTA ;  A4JBK7, ANMK_BURVG ;
DR   Q13UB5, ANMK_BURXL ;  Q9A757, ANMK_CAUCR ;  Q1QT13, ANMK_CHRSD ;
DR   Q7NV67, ANMK_CHRVO ;  Q184N9, ANMK_CLOD6 ;  Q47V03, ANMK_COLP3 ;
DR   B6J4Z9, ANMK_COXB1 ;  B6J2L3, ANMK_COXB2 ;  A9KEL6, ANMK_COXBN ;
DR   A9NAH7, ANMK_COXBR ;  Q83EX9, ANMK_COXBU ;  Q475S7, ANMK_CUPPJ ;
DR   B1WUB0, ANMK_CYAA5 ;  B8HX39, ANMK_CYAP4 ;  B7KIQ6, ANMK_CYAP7 ;
DR   B7K165, ANMK_CYAP8 ;  Q1J3J2, ANMK_DEIGD ;  A7ZMA2, ANMK_ECO24 ;
DR   B7URY1, ANMK_ECO27 ;  B7M9Z4, ANMK_ECO45 ;  B7L5J3, ANMK_ECO55 ;
DR   Q8X644, ANMK_ECO57 ;  B5Z474, ANMK_ECO5E ;  B7NTZ2, ANMK_ECO7I ;
DR   B7MVB8, ANMK_ECO81 ;  B7M0J7, ANMK_ECO8A ;  C4ZYA3, ANMK_ECOBW ;
DR   B1XFV2, ANMK_ECODH ;  A8A0I3, ANMK_ECOHS ;  A1ABI5, ANMK_ECOK1 ;
DR   Q0THI8, ANMK_ECOL5 ;  Q8FH85, ANMK_ECOL6 ;  P77570, ANMK_ECOLI ;
DR   B7NB94, ANMK_ECOLU ;  B6IB79, ANMK_ECOSE ;  B1LEP6, ANMK_ECOSM ;
DR   Q1RBF5, ANMK_ECOUT ;  C5BE34, ANMK_EDWI9 ;  A4W9V7, ANMK_ENT38 ;
DR   A7MMK0, ANMK_ENTS8 ;  Q6D5V5, ANMK_ERWCT ;  B2VEN5, ANMK_ERWT9 ;
DR   B7LQN0, ANMK_ESCF3 ;  A0Q7I7, ANMK_FRATN ;  Q7NEY1, ANMK_GLOVI ;
DR   Q5FSJ7, ANMK_GLUOX ;  P44861, ANMK_HAEIN ;  B8F4V0, ANMK_HAEPS ;
DR   Q2S8Y7, ANMK_HAHCH ;  Q5QVP3, ANMK_IDILO ;  B5XWN7, ANMK_KLEP3 ;
DR   A6T9Y8, ANMK_KLEP7 ;  Q5X5G2, ANMK_LEGPA ;  A5IBP5, ANMK_LEGPC ;
DR   Q5ZVN7, ANMK_LEGPH ;  Q5WWU5, ANMK_LEGPL ;  Q2W2T7, ANMK_MAGSA ;
DR   Q65R57, ANMK_MANSM ;  Q11ED3, ANMK_MESSB ;  B7KT22, ANMK_METC4 ;
DR   B8IS49, ANMK_METNO ;  B1ZHK6, ANMK_METPB ;  B0JSC7, ANMK_MICAN ;
DR   Q5F6H5, ANMK_NEIG1 ;  B4RQI7, ANMK_NEIG2 ;  A9M2L4, ANMK_NEIM0 ;
DR   Q9JSW1, ANMK_NEIMA ;  Q9K118, ANMK_NEIMB ;  A1KVQ5, ANMK_NEIMF ;
DR   Q82UQ3, ANMK_NITEU ;  Q2YBK8, ANMK_NITMU ;  Q3JCM5, ANMK_NITOC ;
DR   Q3SS13, ANMK_NITWN ;  Q8YNP4, ANMK_NOSS1 ;  A6X3N5, ANMK_OCHA4 ;
DR   Q9CK07, ANMK_PASMU ;  C6DK28, ANMK_PECCP ;  Q4FMN4, ANMK_PELUB ;
DR   B4RCQ8, ANMK_PHEZH ;  Q7N3W4, ANMK_PHOLL ;  Q6LRE4, ANMK_PHOPR ;
DR   Q9F7Q9, ANMK_PRB01 ;  A2BZQ6, ANMK_PROM1 ;  A2C698, ANMK_PROM3 ;
DR   A9B9H1, ANMK_PROM4 ;  Q7VEB3, ANMK_PROMA ;  B4EWL8, ANMK_PROMH ;
DR   Q7V5D4, ANMK_PROMM ;  Q46HU0, ANMK_PROMT ;  Q48NN5, ANMK_PSE14 ;
DR   Q15RS7, ANMK_PSEA6 ;  A6UZG7, ANMK_PSEA7 ;  Q9I5Q5, ANMK_PSEAE ;
DR   Q4K515, ANMK_PSEF5 ;  Q3ICY1, ANMK_PSEHT ;  Q3K5W7, ANMK_PSEPF ;
DR   Q88QQ4, ANMK_PSEPK ;  Q889Z1, ANMK_PSESM ;  Q4ZMM5, ANMK_PSEU2 ;
DR   Q4FQ90, ANMK_PSYA2 ;  Q1Q8F6, ANMK_PSYCK ;  Q1LRC5, ANMK_RALME ;
DR   Q8Y241, ANMK_RALSO ;  Q2K7Z9, ANMK_RHIEC ;  Q1MG48, ANMK_RHIL3 ;
DR   Q986R4, ANMK_RHILO ;  Q92PK6, ANMK_RHIME ;  C0ZSV1, ANMK_RHOE4 ;
DR   Q220S7, ANMK_RHOFD ;  Q2IVR1, ANMK_RHOP2 ;  Q6N702, ANMK_RHOPA ;
DR   Q213P4, ANMK_RHOPB ;  Q2RSR4, ANMK_RHORT ;  Q3J3I2, ANMK_RHOS4 ;
DR   Q164E0, ANMK_ROSDO ;  Q21LT1, ANMK_SACD2 ;  B5F6K1, ANMK_SALA4 ;
DR   A9MEH5, ANMK_SALAR ;  Q57PJ1, ANMK_SALCH ;  B5FIF7, ANMK_SALDC ;
DR   B5QV13, ANMK_SALEP ;  B5RAL3, ANMK_SALG2 ;  B4THC3, ANMK_SALHS ;
DR   B4T583, ANMK_SALNS ;  Q5PIK4, ANMK_SALPA ;  A9N037, ANMK_SALPB ;
DR   C0Q5T6, ANMK_SALPC ;  B5BKC3, ANMK_SALPK ;  Q2RZV7, ANMK_SALRD ;
DR   B4TV05, ANMK_SALSV ;  Q8Z6Q0, ANMK_SALTI ;  Q8ZPN1, ANMK_SALTY ;
DR   A8GDX7, ANMK_SERP5 ;  A1S3U9, ANMK_SHEAM ;  B8EBT5, ANMK_SHEB2 ;
DR   A3D1S4, ANMK_SHEB5 ;  A6WKM4, ANMK_SHEB8 ;  A9L5K3, ANMK_SHEB9 ;
DR   Q12KD5, ANMK_SHEDO ;  Q07YV2, ANMK_SHEFN ;  B0TIR7, ANMK_SHEHH ;
DR   A3QBP3, ANMK_SHELP ;  Q8EHB5, ANMK_SHEON ;  A8H183, ANMK_SHEPA ;
DR   A4Y4H1, ANMK_SHEPC ;  B8CQQ1, ANMK_SHEPW ;  A0KZR5, ANMK_SHESA ;
DR   A8FS90, ANMK_SHESH ;  Q0HG64, ANMK_SHESM ;  Q0HSF7, ANMK_SHESR ;
DR   A1RMG0, ANMK_SHESW ;  B1KI25, ANMK_SHEWM ;  B2U2E0, ANMK_SHIB3 ;
DR   Q320Z7, ANMK_SHIBS ;  Q32FD3, ANMK_SHIDS ;  Q0T4D5, ANMK_SHIF8 ;
DR   Q83KX8, ANMK_SHIFL ;  Q3Z1Z6, ANMK_SHISS ;  Q5LQK6, ANMK_SILPO ;
DR   Q1GI59, ANMK_SILST ;  A6U9I7, ANMK_SINMW ;  Q2NT05, ANMK_SODGM ;
DR   A5V6F9, ANMK_SPHWW ;  Q82MF1, ANMK_STRAW ;  Q9EWI9, ANMK_STRCO ;
DR   Q30NT6, ANMK_SULDN ;  A6Q9N6, ANMK_SULNB ;  Q31P96, ANMK_SYNE7 ;
DR   Q2JK57, ANMK_SYNJB ;  B1XMP0, ANMK_SYNP2 ;  Q5N4X3, ANMK_SYNP6 ;
DR   A5GNU1, ANMK_SYNPW ;  Q7U4A1, ANMK_SYNPX ;  Q0I762, ANMK_SYNS3 ;
DR   Q3AZX9, ANMK_SYNS9 ;  Q3AH85, ANMK_SYNSC ;  P74706, ANMK_SYNY3 ;
DR   Q8DGC2, ANMK_THEEB ;  Q8RD30, ANMK_THETN ;  Q31IS6, ANMK_THICR ;
DR   Q3SLK0, ANMK_THIDA ;  C5CM20, ANMK_VARPS ;  Q9KU38, ANMK_VIBCH ;
DR   Q5E084, ANMK_VIBF1 ;  Q87S80, ANMK_VIBPA ;  Q8DET7, ANMK_VIBVU ;
DR   Q7MNL7, ANMK_VIBVY ;  Q8PFS9, ANMK_XANAC ;  Q3BNC0, ANMK_XANC5 ;
DR   Q4UPQ7, ANMK_XANC8 ;  Q8P473, ANMK_XANCP ;  Q2P894, ANMK_XANOM ;
DR   Q5H5K4, ANMK_XANOR ;  A7INU8, ANMK_XANP2 ;  Q9PGY0, ANMK_XYLFA ;
DR   Q87F08, ANMK_XYLFT ;  A1JNW9, ANMK_YERE8 ;  A7FHL7, ANMK_YERP3 ;
DR   Q1C788, ANMK_YERPA ;  Q0WEF0, ANMK_YERPE ;  Q1CIM2, ANMK_YERPN ;
DR   A4TIR8, ANMK_YERPP ;  Q66A46, ANMK_YERPS ;  B1JJ75, ANMK_YERPY ;
DR   Q5NLZ4, ANMK_ZYMMO ;
//
ID   2.7.1.n1
DE   Transferred entry: 2.7.1.170.
//
ID   2.7.1.n2
DE   Transferred entry: 2.7.1.161.
//
ID   2.7.1.n3
DE   Transferred entry: 2.7.1.164.
//
ID   2.7.1.n4
DE   Nicotinamide riboside kinase.
AN   Ribosylnicotinic acid kinase.
CA   ATP + D-ribosylnicotinate = ADP + nicotinate D-ribonucleotide.
CC   -!- The enzyme also phosphorylates the anticancer drug tiazofurin.
DR   P62511, NRK1_ASHGO ;  Q9NWW6, NRK1_HUMAN ;  Q91W63, NRK1_MOUSE ;
DR   Q6AY91, NRK1_RAT   ;  Q9C0W1, NRK1_SCHPO ;  P53915, NRK1_YEAST ;
DR   Q9NPI5, NRK2_HUMAN ;  Q9D7C9, NRK2_MOUSE ;
//
ID   2.7.1.n5
DE   Diacylglycerol kinase (CTP dependent).
AN   DAG kinase.
AN   Diglyceride kinase.
CA   CTP + 1,2-diacyl-sn-glycerol = CDP + 1,2-diacyl-sn-glycerol 3-phosphate.
DR   Q753I3, DGK1_ASHGO ;  P87170, DGK1_SCHPO ;  Q12382, DGK1_YEAST ;
//
ID   2.7.1.n6
DE   Transferred entry: 2.7.1.163.
//
ID   2.7.2.1
DE   Acetate kinase.
AN   Acetate kinase (phosphorylating).
AN   Acetic kinase.
AN   Acetokinase.
AN   AK.
CA   (1) ATP + acetate = ADP + acetyl phosphate.
CA   (2) ATP + propanoate = ADP + propanoyl phosphate.
CF   Magnesium.
CC   -!- While purified enzyme from Escherichia coli is specific for acetate,
CC       others have found that the enzyme can also use propanoate as a
CC       substrate, but more slowly.
CC   -!- Acetate can be converted into the key metabolic intermediate acetyl-
CC       CoA by coupling acetate kinase with EC 2.3.1.8.
CC   -!- Both this enzyme and EC 2.7.2.15 play important roles in the
CC       production of propanoate.
PR   PROSITE; PDOC00826;
DR   Q8XNW5, ACKA1_CLOPE;  Q9CE35, ACKA1_LACLA;  Q9X4M1, ACKA1_LACSS;
DR   Q92BD4, ACKA1_LISIN;  Q720R2, ACKA1_LISMF;  Q8Y6V0, ACKA1_LISMO;
DR   Q9JTM0, ACKA1_NEIMA;  Q9JYM1, ACKA1_NEIMB;  Q6LNF6, ACKA1_PHOPR;
DR   P58382, ACKA1_RHIME;  Q9KT07, ACKA1_VIBCH;  Q5E6L4, ACKA1_VIBF1;
DR   Q87MZ4, ACKA1_VIBPA;  Q8DAH8, ACKA1_VIBVU;  Q7MJM8, ACKA1_VIBVY;
DR   Q8XJN2, ACKA2_CLOPE;  Q9CE36, ACKA2_LACLA;  Q92CN9, ACKA2_LISIN;
DR   Q71Z86, ACKA2_LISMF;  Q8Y7V1, ACKA2_LISMO;  Q9JT07, ACKA2_NEIMA;
DR   Q9K0X1, ACKA2_NEIMB;  Q6LLD4, ACKA2_PHOPR;  Q9X449, ACKA2_RHIME;
DR   Q9KMT5, ACKA2_VIBCH;  Q5DZD2, ACKA2_VIBF1;  Q87IJ5, ACKA2_VIBPA;
DR   Q8D7K4, ACKA2_VIBVU;  Q7MEL2, ACKA2_VIBVY;  B0CB11, ACKA_ACAM1 ;
DR   A9NFI4, ACKA_ACHLI ;  A3N011, ACKA_ACTP2 ;  B3H169, ACKA_ACTP7 ;
DR   B0BNS1, ACKA_ACTPJ ;  A6TRU6, ACKA_ALKMQ ;  B9MJT3, ACKA_ANATD ;
DR   Q3MFX2, ACKA_ANAVT ;  B7GGR2, ACKA_ANOFW ;  B8HF37, ACKA_ARTCA ;
DR   A0JZZ4, ACKA_ARTS2 ;  Q2NIR6, ACKA_AYWBP ;  B6YQE9, ACKA_AZOPC ;
DR   A7Z7M2, ACKA_BACA2 ;  Q81KV0, ACKA_BACAN ;  Q72Z96, ACKA_BACC1 ;
DR   A7GTR9, ACKA_BACCN ;  Q817C0, ACKA_BACCR ;  Q633F8, ACKA_BACCZ ;
DR   Q5LI41, ACKA_BACFN ;  Q64Z48, ACKA_BACFR ;  Q9K815, ACKA_BACHD ;
DR   Q6HCP0, ACKA_BACHK ;  Q65G65, ACKA_BACLD ;  Q5WED5, ACKA_BACSK ;
DR   P37877, ACKA_BACSU ;  Q8A1G8, ACKA_BACTN ;  A6KXS0, ACKA_BACV8 ;
DR   A9VKE9, ACKA_BACWK ;  Q1LT88, ACKA_BAUCH ;  O51567, ACKA_BORBU ;
DR   B7J2I0, ACKA_BORBZ ;  B5RMH1, ACKA_BORDL ;  Q660Q0, ACKA_BORGA ;
DR   B2S0W8, ACKA_BORHD ;  B5RPW7, ACKA_BORRA ;  A1R050, ACKA_BORT9 ;
DR   C0QWN8, ACKA_BRAHW ;  P57272, ACKA_BUCAI ;  Q8K9W6, ACKA_BUCAP ;
DR   Q89AS8, ACKA_BUCBP ;  Q057V8, ACKA_BUCCC ;  A4XL40, ACKA_CALS8 ;
DR   A7ZDP4, ACKA_CAMC1 ;  A7GYC8, ACKA_CAMC5 ;  A0RP54, ACKA_CAMFF ;
DR   A7I2H6, ACKA_CAMHC ;  A8FLB9, ACKA_CAMJ8 ;  A7H4D5, ACKA_CAMJD ;
DR   Q9PPL8, ACKA_CAMJE ;  A1VZ44, ACKA_CAMJJ ;  Q5HV92, ACKA_CAMJR ;
DR   B9KFY4, ACKA_CAMLR ;  Q3AC47, ACKA_CARHZ ;  Q2HAJ4, ACKA_CHAGB ;
DR   O05278, ACKA_CHAYP ;  B3QV27, ACKA_CHLT3 ;  Q7NXU5, ACKA_CHRVO ;
DR   A5CPD5, ACKA_CLAM3 ;  B0RIG4, ACKA_CLAMS ;  P71104, ACKA_CLOAB ;
DR   A7FW24, ACKA_CLOB1 ;  C3L0F7, ACKA_CLOB6 ;  A6LSL7, ACKA_CLOB8 ;
DR   B2V4D1, ACKA_CLOBA ;  B2TJ17, ACKA_CLOBB ;  A5I4N7, ACKA_CLOBH ;
DR   C1FSN0, ACKA_CLOBJ ;  B1II90, ACKA_CLOBK ;  A7GG48, ACKA_CLOBL ;
DR   B1KWP9, ACKA_CLOBM ;  B8I447, ACKA_CLOCE ;  Q18B36, ACKA_CLOD6 ;
DR   A5N802, ACKA_CLOK5 ;  A0Q0Z5, ACKA_CLONN ;  A9KNV3, ACKA_CLOPH ;
DR   Q895N2, ACKA_CLOTE ;  O52594, ACKA_CLOTH ;  B5Y7W0, ACKA_COPPD ;
DR   C3PJJ2, ACKA_CORA7 ;  Q6NF47, ACKA_CORDI ;  Q8FMB7, ACKA_COREF ;
DR   A4QHF4, ACKA_CORGB ;  P77845, ACKA_CORGL ;  Q4JXQ4, ACKA_CORJK ;
DR   P0CL99, ACKA_CRYNB ;  P0CL98, ACKA_CRYNJ ;  B8HVB6, ACKA_CYAP4 ;
DR   B7KGG9, ACKA_CYAP7 ;  B7K4D0, ACKA_CYAP8 ;  C1D087, ACKA_DEIDV ;
DR   Q1J2C9, ACKA_DEIGD ;  Q9RR92, ACKA_DEIRA ;  C6BYL8, ACKA_DESAD ;
DR   B8J374, ACKA_DESDA ;  Q30WB0, ACKA_DESDG ;  B8FRT2, ACKA_DESHD ;
DR   Q24U35, ACKA_DESHY ;  Q6AQT5, ACKA_DESPS ;  A4J6A8, ACKA_DESRM ;
DR   Q726S6, ACKA_DESVH ;  B8DMG5, ACKA_DESVM ;  A1VAA0, ACKA_DESVV ;
DR   A5EVU0, ACKA_DICNV ;  B5YDP7, ACKA_DICT6 ;  B8E191, ACKA_DICTD ;
DR   P0A6A5, ACKA_ECO57 ;  P0A6A4, ACKA_ECOL6 ;  P0A6A3, ACKA_ECOLI ;
DR   Q5B3G6, ACKA_EMENI ;  Q833H0, ACKA_ENTFA ;  A7MH28, ACKA_ENTS8 ;
DR   Q6D2Q6, ACKA_ERWCT ;  B2VIP6, ACKA_ERWT9 ;  C4Z917, ACKA_EUBR3 ;
DR   B1YKC5, ACKA_EXIS2 ;  C4L493, ACKA_EXISA ;  A7HL30, ACKA_FERNB ;
DR   B0S1N0, ACKA_FINM2 ;  A5FE24, ACKA_FLAJ1 ;  Q0BPA5, ACKA_FRATO ;
DR   Q8RED7, ACKA_FUSNN ;  C1A9T6, ACKA_GEMAT ;  Q5KW66, ACKA_GEOKA ;
DR   B3EB76, ACKA_GEOLS ;  Q39WV0, ACKA_GEOMG ;  Q749N5, ACKA_GEOSL ;
DR   C5D683, ACKA_GEOSW ;  Q7NLW9, ACKA_GLOVI ;  Q7VLI5, ACKA_HAEDU ;
DR   Q4QL95, ACKA_HAEI8 ;  A5UCQ6, ACKA_HAEIE ;  A5UIW8, ACKA_HAEIG ;
DR   P44406, ACKA_HAEIN ;  B8F420, ACKA_HAEPS ;  Q0I3R3, ACKA_HAES1 ;
DR   B0UTZ5, ACKA_HAES2 ;  B8CWV8, ACKA_HALOH ;  Q17WE3, ACKA_HELAH ;
DR   Q7VGL3, ACKA_HELHP ;  B0TGV2, ACKA_HELMI ;  Q9ZKU5, ACKA_HELPJ ;
DR   B2UU54, ACKA_HELPS ;  B2GKK6, ACKA_KOCRD ;  Q03CP2, ACKA_LACC3 ;
DR   B2GB54, ACKA_LACF3 ;  Q88V41, ACKA_LACPL ;  Q9F1X7, ACKA_LACSN ;
DR   Q1MRP0, ACKA_LAWIP ;  Q6AGY7, ACKA_LEIXX ;  B9E7B7, ACKA_MACCJ ;
DR   Q65TV4, ACKA_MANSM ;  Q6F273, ACKA_MESFL ;  Q8TK19, ACKA_METAC ;
DR   Q46BI1, ACKA_METBF ;  P0CW05, ACKA_METMA ;  P0CW04, ACKA_METMZ ;
DR   B8EIS2, ACKA_METSB ;  P38502, ACKA_METTE ;  B0JMT8, ACKA_MICAN ;
DR   C5C8D9, ACKA_MICLC ;  Q2RJY3, ACKA_MOOTA ;  P63410, ACKA_MYCBO ;
DR   Q49113, ACKA_MYCCT ;  Q7NAZ6, ACKA_MYCGA ;  P47599, ACKA_MYCGE ;
DR   A4T166, ACKA_MYCGI ;  Q6MTX5, ACKA_MYCMS ;  P75245, ACKA_MYCPN ;
DR   Q98QX2, ACKA_MYCPU ;  A3PTW3, ACKA_MYCSJ ;  A1UAA8, ACKA_MYCSK ;
DR   Q1BEM5, ACKA_MYCSS ;  P63409, ACKA_MYCTU ;  A1T2Y9, ACKA_MYCVP ;
DR   B2A8I5, ACKA_NATTJ ;  Q7SH17, ACKA_NEUCR ;  Q1QPW6, ACKA_NITHX ;
DR   Q5YNP4, ACKA_NOCFA ;  B2J068, ACKA_NOSP7 ;  Q8YU00, ACKA_NOSS1 ;
DR   Q8EPB9, ACKA_OCEIH ;  Q6YR57, ACKA_ONYPE ;  A6LHA9, ACKA_PARD8 ;
DR   Q6MBG3, ACKA_PARUW ;  P57866, ACKA_PASMU ;  C6DA54, ACKA_PECCP ;
DR   Q7N2I1, ACKA_PHOLL ;  B1V924, ACKA_PHYAS ;  B3QZW9, ACKA_PHYMT ;
DR   B2RK02, ACKA_PORG3 ;  Q7MVI0, ACKA_PORGI ;  B4EZD9, ACKA_PROMH ;
DR   A6VAE3, ACKA_PSEA7 ;  B7UYA0, ACKA_PSEA8 ;  Q02HZ4, ACKA_PSEAB ;
DR   Q9I5A4, ACKA_PSEAE ;  A4XYH6, ACKA_PSEMY ;  A4VIM1, ACKA_PSEU5 ;
DR   Q6N143, ACKA_RHOPA ;  B3QA57, ACKA_RHOPT ;  A8GM71, ACKA_RICAH ;
DR   Q4UNB0, ACKA_RICFE ;  Q9ZE38, ACKA_RICPR ;  Q68XX8, ACKA_RICTY ;
DR   P63412, ACKA_SALTI ;  P63411, ACKA_SALTY ;  A8GH24, ACKA_SERP5 ;
DR   A1S5P6, ACKA_SHEAM ;  B8EEJ1, ACKA_SHEB2 ;  A3D600, ACKA_SHEB5 ;
DR   A6WPT9, ACKA_SHEB8 ;  A9L605, ACKA_SHEB9 ;  Q080J4, ACKA_SHEFN ;
DR   A3QFL1, ACKA_SHELP ;  Q8ED55, ACKA_SHEON ;  A8H356, ACKA_SHEPA ;
DR   A4Y819, ACKA_SHEPC ;  A0KVG7, ACKA_SHESA ;  Q0HK48, ACKA_SHESM ;
DR   Q0HWE9, ACKA_SHESR ;  A1RIH0, ACKA_SHESW ;  B1KJX4, ACKA_SHEWM ;
DR   Q2NSJ4, ACKA_SODGM ;  Q022T0, ACKA_SOLUE ;  A7X3E0, ACKA_STAA1 ;
DR   A6U2H8, ACKA_STAA2 ;  Q2FG27, ACKA_STAA3 ;  Q2FXL5, ACKA_STAA8 ;
DR   A5ITN4, ACKA_STAA9 ;  Q2YTC9, ACKA_STAAB ;  Q5HF63, ACKA_STAAC ;
DR   A6QHP5, ACKA_STAAE ;  Q931P6, ACKA_STAAM ;  Q99TF2, ACKA_STAAN ;
DR   Q6GFZ6, ACKA_STAAR ;  Q6G8L6, ACKA_STAAS ;  A8Z2M7, ACKA_STAAT ;
DR   Q8NW53, ACKA_STAAW ;  B9DN93, ACKA_STACT ;  Q5HNJ4, ACKA_STAEQ ;
DR   Q8CS60, ACKA_STAES ;  Q4L752, ACKA_STAHJ ;  Q49YE2, ACKA_STAS1 ;
DR   Q3K3K1, ACKA_STRA1 ;  Q8E7I7, ACKA_STRA3 ;  Q8E231, ACKA_STRA5 ;
DR   Q82JD1, ACKA_STRAW ;  Q9L298, ACKA_STRCO ;  C0M6X6, ACKA_STRE4 ;
DR   B4U063, ACKA_STREM ;  A8AZH2, ACKA_STRGC ;  B1W052, ACKA_STRGG ;
DR   Q8DS57, ACKA_STRMU ;  P63415, ACKA_STRP1 ;  Q04IC8, ACKA_STRP2 ;
DR   P0CZ46, ACKA_STRP3 ;  B5E2W4, ACKA_STRP4 ;  Q5XE86, ACKA_STRP6 ;
DR   C1CA89, ACKA_STRP7 ;  Q8P2X6, ACKA_STRP8 ;  Q1JE09, ACKA_STRPB ;
DR   Q1JNW6, ACKA_STRPC ;  Q1JJ12, ACKA_STRPD ;  Q1J8W0, ACKA_STRPF ;
DR   A2RC62, ACKA_STRPG ;  B1I9A0, ACKA_STRPI ;  B8ZPA4, ACKA_STRPJ ;
DR   Q48VQ0, ACKA_STRPM ;  P63413, ACKA_STRPN ;  P0CZ47, ACKA_STRPQ ;
DR   B5XJD9, ACKA_STRPZ ;  P63414, ACKA_STRR6 ;  C0MEF7, ACKA_STRS7 ;
DR   A4VSL6, ACKA_STRSY ;  Q03IL2, ACKA_STRTD ;  B9DT06, ACKA_STRU0 ;
DR   C1CGX4, ACKA_STRZJ ;  C1CMZ0, ACKA_STRZP ;  C1CTV0, ACKA_STRZT ;
DR   Q30UJ4, ACKA_SULDN ;  A6QBT0, ACKA_SULNB ;  Q67L76, ACKA_SYMTH ;
DR   A0LIB0, ACKA_SYNFM ;  Q2JRF6, ACKA_SYNJA ;  Q2JLQ2, ACKA_SYNJB ;
DR   Q0AYW5, ACKA_SYNWW ;  P73162, ACKA_SYNY3 ;  B7IDH3, ACKA_THEAB ;
DR   Q8DGH7, ACKA_THEEB ;  A8F3X9, ACKA_THELT ;  A6LMG9, ACKA_THEM4 ;
DR   Q9WYB1, ACKA_THEMA ;  A5IKE7, ACKA_THEP1 ;  B0K9Y6, ACKA_THEP3 ;
DR   B1L9M9, ACKA_THESQ ;  Q59331, ACKA_THETC ;  Q8R9V4, ACKA_THETN ;
DR   Q73P66, ACKA_TREDE ;  O83489, ACKA_TREPA ;  B2S371, ACKA_TREPS ;
DR   B1GZX0, ACKA_UNCTG ;  A7MVE1, ACKA_VIBHB ;  Q8D320, ACKA_WIGBR ;
DR   A7FGP4, ACKA_YERP3 ;  Q1C6A1, ACKA_YERPA ;  B2K830, ACKA_YERPB ;
DR   Q8ZDJ6, ACKA_YERPE ;  A9R6M9, ACKA_YERPG ;  Q1CHP3, ACKA_YERPN ;
DR   A4TM44, ACKA_YERPP ;  Q668Z0, ACKA_YERPS ;  B1JGK4, ACKA_YERPY ;
//
ID   2.7.2.2
DE   Carbamate kinase.
CA   ATP + NH(3) + CO(2) = ADP + carbamoyl phosphate.
DR   P0A2X7, ARCC1_ENTFA;  P0A2X8, ARCC1_ENTFC;  Q2FHR7, ARCC1_STAA3;
DR   Q2FZA9, ARCC1_STAA8;  Q2YXF2, ARCC1_STAAB;  Q5HGR2, ARCC1_STAAC;
DR   Q99UU0, ARCC1_STAAM;  Q7A627, ARCC1_STAAN;  Q6GHR6, ARCC1_STAAR;
DR   Q6GA44, ARCC1_STAAS;  Q7A138, ARCC1_STAAW;  Q8CTX1, ARCC1_STAES;
DR   P59625, ARCC2_ENTFA;  Q2FDM7, ARCC2_STAA3;  Q7X2S2, ARCC2_STAA8;
DR   Q2YWH4, ARCC2_STAAB;  Q5HCR5, ARCC2_STAAC;  P63555, ARCC2_STAAM;
DR   P99069, ARCC2_STAAN;  Q6GDH0, ARCC2_STAAR;  Q6G642, ARCC2_STAAS;
DR   P63556, ARCC2_STAAW;  Q8CU42, ARCC2_STAES;  Q2FKJ8, ARCC3_STAA3;
DR   O86134, ARCC_BACLD ;  Q46171, ARCC_CLOPE ;  Q8XCV5, ARCC_ECO57 ;
DR   Q8FK51, ARCC_ECOL6 ;  P37306, ARCC_ECOLI ;  P44769, ARCC_HAEIN ;
DR   Q48295, ARCC_HALSA ;  Q8G997, ARCC_LACHI ;  O53090, ARCC_LACSK ;
DR   Q8VW54, ARCC_OENOE ;  P13982, ARCC_PSEAE ;  O31019, ARCC_RHIET ;
DR   Q92ZT0, ARCC_RHIME ;  Q5HKJ3, ARCC_STAEQ ;  Q4L9V7, ARCC_STAHJ ;
DR   P74733, ARCC_SYNY3 ;  Q9HII9, ARCC_THEAC ;  Q97C45, ARCC_THEVO ;
DR   O97438, CBK_GIAIN  ;  O96432, CBK_TRIVA  ;  Q9UWF8, CPKA_PYRAB ;
DR   P95474, CPKA_PYRFU ;  O59023, CPKA_PYRHO ;  Q5JHG5, CPKA_PYRKO ;
//
ID   2.7.2.3
DE   Phosphoglycerate kinase.
CA   ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.
PR   PROSITE; PDOC00102;
DR   Q3T0P6, PGK1_BOVIN ;  P50310, PGK1_CRIGR ;  P00559, PGK1_HORSE ;
DR   P00558, PGK1_HUMAN ;  P29408, PGK1_MACEU ;  Q60HD8, PGK1_MACFA ;
DR   Q8TMI8, PGK1_METAC ;  P09411, PGK1_MOUSE ;  A5A6K4, PGK1_PANTR ;
DR   Q7SIB7, PGK1_PIG   ;  Q5NVB5, PGK1_PONAB ;  P16617, PGK1_RAT   ;
DR   P29405, PGK1_RHINI ;  P41760, PGK1_TRYCO ;  Q8MIF7, PGK2_HORSE ;
DR   P07205, PGK2_HUMAN ;  Q4R3K4, PGK2_MACFA ;  Q8TK32, PGK2_METAC ;
DR   P09041, PGK2_MOUSE ;  Q6RI85, PGK2_PIG   ;  P29406, PGK2_RHINI ;
DR   P25055, PGKA_CRIFA ;  P08891, PGKA_TRYBB ;  P08966, PGKB_CRIFA ;
DR   Q27683, PGKB_LEIMA ;  Q27684, PGKB_LEIME ;  P07377, PGKB_TRYBB ;
DR   P08967, PGKC_CRIFA ;  P50319, PGKC_CUPNH ;  P50312, PGKC_LEIMA ;
DR   Q27685, PGKC_LEIME ;  P07378, PGKC_TRYBB ;  P08892, PGKD_TRYBB ;
DR   P08893, PGKE_TRYBB ;  P41762, PGKG_TRYCO ;  Q9LD57, PGKH1_ARATH;
DR   P50318, PGKH2_ARATH;  P36232, PGKH_CHLFU ;  P41758, PGKH_CHLRE ;
DR   P80659, PGKH_PHYPA ;  P29409, PGKH_SPIOL ;  Q42961, PGKH_TOBAC ;
DR   Q9SBN4, PGKH_VOLCA ;  P12782, PGKH_WHEAT ;  P50320, PGKP_CUPNH ;
DR   P36204, PGKT_THEMA ;  Q42962, PGKY_TOBAC ;  P12783, PGKY_WHEAT ;
DR   B0CD95, PGK_ACAM1  ;  A9NHH8, PGK_ACHLI  ;  A1TW90, PGK_ACIAC  ;
DR   Q6FB08, PGK_ACIAD  ;  B7H3N8, PGK_ACIB3  ;  B7I501, PGK_ACIB5  ;
DR   B2HZB6, PGK_ACIBC  ;  Q1INK7, PGK_ACIBL  ;  B0VMX3, PGK_ACIBS  ;
DR   A3M4X6, PGK_ACIBT  ;  B0VD03, PGK_ACIBY  ;  C1F1M9, PGK_ACIC5  ;
DR   B9MI90, PGK_ACIET  ;  B7JBC8, PGK_ACIF2  ;  B5ERJ0, PGK_ACIF5  ;
DR   A1WD35, PGK_ACISJ  ;  A3N1Q1, PGK_ACTP2  ;  B3H222, PGK_ACTP7  ;
DR   B0BQI3, PGK_ACTPJ  ;  A6VLR3, PGK_ACTSZ  ;  A0KGD3, PGK_AERHH  ;
DR   Q9YFS7, PGK_AERPE  ;  A4SRF1, PGK_AERS4  ;  O94123, PGK_AGABI  ;
DR   Q8U9I9, PGK_AGRT5  ;  B9JS00, PGK_AGRVS  ;  B2UKW8, PGK_AKKM8  ;
DR   Q0VL87, PGK_ALCBS  ;  Q0A4Q5, PGK_ALHEH  ;  B6EMW2, PGK_ALISL  ;
DR   B8JBD5, PGK_ANAD2  ;  Q2II25, PGK_ANADE  ;  A7HCN7, PGK_ANADF  ;
DR   B4UEJ2, PGK_ANASK  ;  Q3MF40, PGK_ANAVT  ;  B7GL27, PGK_ANOFW  ;
DR   O61471, PGK_APLCA  ;  O66519, PGK_AQUAE  ;  A8EWM4, PGK_ARCB4  ;
DR   O29119, PGK_ARCFU  ;  Q5P7K8, PGK_AROAE  ;  A1R6H1, PGK_ARTAT  ;
DR   B8H7M5, PGK_ARTCA  ;  A0JWP8, PGK_ARTS2  ;  Q757Q0, PGK_ASHGO  ;
DR   P41756, PGK_ASPOR  ;  A8IM75, PGK_AZOC5  ;  A1K9F0, PGK_AZOSB  ;
DR   C1DKE9, PGK_AZOVD  ;  C3P0A6, PGK_BACAA  ;  C3LDI3, PGK_BACAC  ;
DR   A0RKS6, PGK_BACAH  ;  Q81X75, PGK_BACAN  ;  B7JFG6, PGK_BACC0  ;
DR   P62409, PGK_BACC1  ;  B7IP23, PGK_BACC2  ;  C1EZA3, PGK_BACC3  ;
DR   B7HED5, PGK_BACC4  ;  B7HW55, PGK_BACC7  ;  P83075, PGK_BACCE  ;
DR   A7GUS0, PGK_BACCN  ;  B9J4M7, PGK_BACCQ  ;  Q631L9, PGK_BACCZ  ;
DR   Q9K714, PGK_BACHD  ;  Q6HBF0, PGK_BACHK  ;  Q65EM9, PGK_BACLD  ;
DR   P24269, PGK_BACMD  ;  A8FHJ3, PGK_BACP2  ;  Q5WDK6, PGK_BACSK  ;
DR   P40924, PGK_BACSU  ;  Q8A753, PGK_BACTN  ;  A9VQ51, PGK_BACWK  ;
DR   A1UR75, PGK_BARBK  ;  Q8L1Z8, PGK_BARHE  ;  Q6FYN4, PGK_BARQU  ;
DR   A9IYR6, PGK_BART1  ;  Q1LSJ6, PGK_BAUCH  ;  P62410, PGK_BDEBA  ;
DR   C5BV35, PGK_BEUC1  ;  A1A1N3, PGK_BIFAA  ;  B3DRV9, PGK_BIFLD  ;
DR   Q8G6D6, PGK_BIFLO  ;  B7GQU7, PGK_BIFLS  ;  Q7VRG3, PGK_BLOFL  ;
DR   Q493F0, PGK_BLOPB  ;  Q0SPA9, PGK_BORAP  ;  Q7WMK9, PGK_BORBR  ;
DR   Q59181, PGK_BORBU  ;  B7J0Z2, PGK_BORBZ  ;  B5RKV5, PGK_BORDL  ;
DR   Q662V8, PGK_BORGA  ;  B2S1P1, PGK_BORHD  ;  Q7WB43, PGK_BORPA  ;
DR   Q7VZB8, PGK_BORPE  ;  B5RQN5, PGK_BORRA  ;  A1QYK6, PGK_BORT9  ;
DR   Q89U95, PGK_BRAJA  ;  C0Z6L6, PGK_BREBN  ;  Q9L560, PGK_BRUAB  ;
DR   Q8YIY0, PGK_BRUME  ;  Q8FYX8, PGK_BRUSU  ;  B8D9M8, PGK_BUCA5  ;
DR   P57525, PGK_BUCAI  ;  Q8K9B3, PGK_BUCAP  ;  B8D7Y0, PGK_BUCAT  ;
DR   P59461, PGK_BUCBP  ;  P91427, PGK_CAEEL  ;  A7ZEZ5, PGK_CAMC1  ;
DR   A7GWT1, PGK_CAMC5  ;  A0RQT4, PGK_CAMFF  ;  A7I1G1, PGK_CAMHC  ;
DR   A8FN77, PGK_CAMJ8  ;  A7H5C5, PGK_CAMJD  ;  Q9PMQ5, PGK_CAMJE  ;
DR   A1W116, PGK_CAMJJ  ;  Q5HT15, PGK_CAMJR  ;  B9KFD9, PGK_CAMLR  ;
DR   P46273, PGK_CANAL  ;  Q6FKY1, PGK_CANGA  ;  P41757, PGK_CANMA  ;
DR   Q3AFD1, PGK_CARHZ  ;  B8H4J9, PGK_CAUCN  ;  Q9A3F5, PGK_CAUCR  ;
DR   B0SUL9, PGK_CAUSK  ;  B3PGF6, PGK_CELJU  ;  P51903, PGK_CHICK  ;
DR   A9WKE4, PGK_CHLAA  ;  Q5L748, PGK_CHLAB  ;  B8G4H3, PGK_CHLAD  ;
DR   Q3ANU2, PGK_CHLCH  ;  Q824S8, PGK_CHLCV  ;  Q252S3, PGK_CHLFF  ;
DR   B3EIM1, PGK_CHLL2  ;  Q9PLN4, PGK_CHLMU  ;  B3QLX7, PGK_CHLP8  ;
DR   B3EQD1, PGK_CHLPB  ;  A1BJZ1, PGK_CHLPD  ;  Q9Z7M5, PGK_CHLPN  ;
DR   B9LM50, PGK_CHLSY  ;  B0B8R9, PGK_CHLT2  ;  B3QWD9, PGK_CHLT3  ;
DR   Q3KL01, PGK_CHLTA  ;  B0BAE8, PGK_CHLTB  ;  Q8KAE1, PGK_CHLTE  ;
DR   P0CD78, PGK_CHLTR  ;  Q7P1M4, PGK_CHRVO  ;  A5CRT6, PGK_CLAM3  ;
DR   B0REJ2, PGK_CLAMS  ;  O52632, PGK_CLOAB  ;  A7FQN7, PGK_CLOB1  ;
DR   C3KYR4, PGK_CLOB6  ;  A6LR05, PGK_CLOB8  ;  B2UY23, PGK_CLOBA  ;
DR   B2TPX4, PGK_CLOBB  ;  A5HYC0, PGK_CLOBH  ;  C1FQW3, PGK_CLOBJ  ;
DR   B1IDB6, PGK_CLOBK  ;  A7G9Y0, PGK_CLOBL  ;  B1KTJ5, PGK_CLOBM  ;
DR   Q181T8, PGK_CLOD6  ;  B9E6B4, PGK_CLOK1  ;  A5N2N8, PGK_CLOK5  ;
DR   A0PYP1, PGK_CLONN  ;  Q0TQY7, PGK_CLOP1  ;  P81346, PGK_CLOPA  ;
DR   Q8XKU0, PGK_CLOPE  ;  Q0STD5, PGK_CLOPS  ;  Q898R3, PGK_CLOTE  ;
DR   Q47XD4, PGK_COLP3  ;  O00940, PGK_CONMG  ;  B5Y8I0, PGK_COPPD  ;
DR   C3PG40, PGK_CORA7  ;  P62411, PGK_CORDI  ;  Q8FT66, PGK_COREF  ;
DR   A4QEG1, PGK_CORGB  ;  Q01655, PGK_CORGL  ;  Q4JVJ3, PGK_CORJK  ;
DR   C4LIR6, PGK_CORK4  ;  B1VDQ4, PGK_CORU7  ;  Q83AU6, PGK_COXBU  ;
DR   B8HXQ5, PGK_CYAP4  ;  B7K9Q5, PGK_CYAP7  ;  B7JVE4, PGK_CYAP8  ;
DR   Q6BLA0, PGK_DEBHA  ;  Q47A08, PGK_DECAR  ;  C1CV29, PGK_DEIDV  ;
DR   Q1IZA3, PGK_DEIGD  ;  Q9RUP2, PGK_DEIRA  ;  B8FJP4, PGK_DESAA  ;
DR   C6BUI7, PGK_DESAD  ;  C0Q9Z7, PGK_DESAH  ;  B1I0X7, PGK_DESAP  ;
DR   B8J4D3, PGK_DESDA  ;  A8ZUS4, PGK_DESOH  ;  Q6AS45, PGK_DESPS  ;
DR   P62412, PGK_DESVH  ;  B8DPM3, PGK_DESVM  ;  A1VBC3, PGK_DESVV  ;
DR   Q9GPM4, PGK_DICDI  ;  B5YE95, PGK_DICT6  ;  B8E2D3, PGK_DICTD  ;
DR   A8LQM4, PGK_DINSH  ;  Q01604, PGK_DROME  ;  A7ZR34, PGK_ECO24  ;
DR   Q8XD03, PGK_ECO57  ;  A8A466, PGK_ECOHS  ;  A1AFB0, PGK_ECOK1  ;
DR   Q0TDT0, PGK_ECOL5  ;  P0A7A0, PGK_ECOL6  ;  B1IT77, PGK_ECOLC  ;
DR   P0A799, PGK_ECOLI  ;  B2KC44, PGK_ELUMP  ;  P11977, PGK_EMENI  ;
DR   A4WE71, PGK_ENT38  ;  Q833I9, PGK_ENTFA  ;  A7MJQ4, PGK_ENTS8  ;
DR   Q6D087, PGK_ERWCT  ;  B2VF23, PGK_ERWT9  ;  O02608, PGK_EUPCR  ;
DR   B1YLE1, PGK_EXIS2  ;  C4L5H7, PGK_EXISA  ;  A7HL11, PGK_FERNB  ;
DR   B0S1H0, PGK_FINM2  ;  Q0RH06, PGK_FRAAA  ;  B0TY21, PGK_FRAP2  ;
DR   Q2JCH8, PGK_FRASC  ;  A8KYR5, PGK_FRASN  ;  Q14GM9, PGK_FRAT1  ;
DR   A7NCI3, PGK_FRATF  ;  Q2A369, PGK_FRATH  ;  B2SFU7, PGK_FRATM  ;
DR   A0Q7J1, PGK_FRATN  ;  Q0BLP2, PGK_FRATO  ;  Q5NF76, PGK_FRATT  ;
DR   A4IWY7, PGK_FRATW  ;  Q8RFN7, PGK_FUSNN  ;  B5EF40, PGK_GEOBB  ;
DR   Q5KVE4, PGK_GEOKA  ;  B3E9Q7, PGK_GEOLS  ;  Q39U98, PGK_GEOMG  ;
DR   P18912, PGK_GEOSE  ;  B9M2C3, PGK_GEOSF  ;  C6E770, PGK_GEOSM  ;
DR   C5D7M4, PGK_GEOSW  ;  A5G382, PGK_GEOUR  ;  O00852, PGK_GLACH  ;
DR   O74233, PGK_GLOMO  ;  Q7NI70, PGK_GLOVI  ;  Q5FTL1, PGK_GLUOX  ;
DR   Q0BVE2, PGK_GRABC  ;  Q7VMV0, PGK_HAEDU  ;  Q4QN23, PGK_HAEI8  ;
DR   A5U9X0, PGK_HAEIE  ;  A5UH30, PGK_HAEIG  ;  P43726, PGK_HAEIN  ;
DR   B0UV33, PGK_HAES2  ;  Q2SLS9, PGK_HAHCH  ;  A1WVV5, PGK_HALHL  ;
DR   B9LSK0, PGK_HALLT  ;  Q5UZX1, PGK_HALMA  ;  B0R548, PGK_HALS3  ;
DR   Q9HQD1, PGK_HALSA  ;  P50315, PGK_HALVA  ;  Q7VJB6, PGK_HELHP  ;
DR   Q9ZJP1, PGK_HELPJ  ;  P56154, PGK_HELPY  ;  A9B312, PGK_HERA2  ;
DR   A4G895, PGK_HERAR  ;  B4U8G5, PGK_HYDS0  ;  A6T1Z0, PGK_JANMA  ;
DR   Q28RQ1, PGK_JANSC  ;  A6WC55, PGK_KINRD  ;  B5XUB8, PGK_KLEP3  ;
DR   P14828, PGK_KLULA  ;  Q5FL50, PGK_LACAC  ;  Q03SL7, PGK_LACBA  ;
DR   Q03AK6, PGK_LACC3  ;  B3WCW5, PGK_LACCB  ;  Q1GB26, PGK_LACDA  ;
DR   Q04BH1, PGK_LACDB  ;  O32756, PGK_LACDE  ;  Q8GIZ5, PGK_LACDL  ;
DR   B2GAL8, PGK_LACF3  ;  Q042F2, PGK_LACGA  ;  A8YUE3, PGK_LACH4  ;
DR   P62413, PGK_LACJO  ;  Q9CIW1, PGK_LACLA  ;  A2RHX1, PGK_LACLM  ;
DR   Q032K6, PGK_LACLS  ;  Q88YH5, PGK_LACPL  ;  B2G616, PGK_LACRJ  ;
DR   Q1WTB5, PGK_LACS1  ;  Q38Y20, PGK_LACSS  ;  C1D9S8, PGK_LARHH  ;
DR   Q5X8U1, PGK_LEGPA  ;  A5I9V7, PGK_LEGPC  ;  Q5ZZ74, PGK_LEGPH  ;
DR   Q5X084, PGK_LEGPL  ;  Q6AF44, PGK_LEIXX  ;  B0SB21, PGK_LEPBA  ;
DR   Q04TE9, PGK_LEPBJ  ;  Q052H7, PGK_LEPBL  ;  B0SSU3, PGK_LEPBP  ;
DR   B1XWA3, PGK_LEPCP  ;  P62414, PGK_LEPIC  ;  Q8F5H8, PGK_LEPIN  ;
DR   B1MW69, PGK_LEUCK  ;  Q03UX8, PGK_LEUMM  ;  Q928I0, PGK_LISIN  ;
DR   C1KY97, PGK_LISMC  ;  Q71WW8, PGK_LISMF  ;  B8DD98, PGK_LISMH  ;
DR   Q8Y4I2, PGK_LISMO  ;  A0ALE2, PGK_LISW6  ;  B9EAG8, PGK_MACCJ  ;
DR   Q65W08, PGK_MANSM  ;  A1U543, PGK_MARAV  ;  Q0ALG1, PGK_MARMM  ;
DR   A6W3D3, PGK_MARMS  ;  Q11CR7, PGK_MESSB  ;  P20972, PGK_METBR  ;
DR   B7KNP6, PGK_METC4  ;  Q606J5, PGK_METCA  ;  A9W5A7, PGK_METEP  ;
DR   Q1GZ23, PGK_METFK  ;  P20971, PGK_METFV  ;  Q58058, PGK_METJA  ;
DR   Q8TUU1, PGK_METKA  ;  A2SSW4, PGK_METLZ  ;  Q8PZK7, PGK_METMA  ;
DR   P62423, PGK_METMP  ;  B1Z980, PGK_METPB  ;  B1M787, PGK_METRJ  ;
DR   A4YHA6, PGK_METS5  ;  O27121, PGK_METTH  ;  B0JT86, PGK_MICAN  ;
DR   C5CBP5, PGK_MICLC  ;  Q2RLU1, PGK_MOOTA  ;  A0QHY4, PGK_MYCA1  ;
DR   B1MC86, PGK_MYCA9  ;  O32848, PGK_MYCAV  ;  P65701, PGK_MYCBO  ;
DR   A1KIM6, PGK_MYCBP  ;  C1AN82, PGK_MYCBT  ;  Q7NBG7, PGK_MYCGA  ;
DR   P47542, PGK_MYCGE  ;  A4TC15, PGK_MYCGI  ;  Q7WZ28, PGK_MYCH2  ;
DR   B8ZUP2, PGK_MYCLB  ;  P46712, PGK_MYCLE  ;  B2HP85, PGK_MYCMM  ;
DR   P62415, PGK_MYCMS  ;  P62416, PGK_MYCPA  ;  Q8EUV2, PGK_MYCPE  ;
DR   P78018, PGK_MYCPN  ;  Q98QW4, PGK_MYCPU  ;  A0QWW3, PGK_MYCS2  ;
DR   A3PZA2, PGK_MYCSJ  ;  A1UFP0, PGK_MYCSK  ;  Q1B9C1, PGK_MYCSS  ;
DR   A5U2D9, PGK_MYCTA  ;  P65700, PGK_MYCTU  ;  A0PPN3, PGK_MYCUA  ;
DR   A1T8L1, PGK_MYCVP  ;  Q3INZ6, PGK_NATPD  ;  B9L8C3, PGK_NAUPA  ;
DR   Q5F5K5, PGK_NEIG1  ;  B4RPR1, PGK_NEIG2  ;  A9LZI3, PGK_NEIM0  ;
DR   Q9JWS8, PGK_NEIMA  ;  Q9K1R0, PGK_NEIMB  ;  A1KWN6, PGK_NEIMF  ;
DR   P38667, PGK_NEUCR  ;  Q0AFQ9, PGK_NITEC  ;  Q82XE8, PGK_NITEU  ;
DR   Q2YC27, PGK_NITMU  ;  Q3J7E3, PGK_NITOC  ;  A6Q539, PGK_NITSB  ;
DR   Q5YTQ5, PGK_NOCFA  ;  B2ITU1, PGK_NOSP7  ;  Q8YPR1, PGK_NOSS1  ;
DR   Q2G6W8, PGK_NOVAD  ;  Q8ENP3, PGK_OCEIH  ;  Q04G42, PGK_OENOB  ;
DR   P62417, PGK_ONYPE  ;  P50311, PGK_OPISI  ;  A5CDP5, PGK_ORITB  ;
DR   B3CQC3, PGK_ORITI  ;  O02609, PGK_OXYNO  ;  O00869, PGK_PARPR  ;
DR   P57973, PGK_PASMU  ;  C6DFH7, PGK_PECCP  ;  Q03GW7, PGK_PEDPA  ;
DR   Q3B116, PGK_PELLD  ;  B4SHF6, PGK_PELPB  ;  A1APN7, PGK_PELPD  ;
DR   A5CYN8, PGK_PELTS  ;  P09188, PGK_PENCH  ;  P33161, PGK_PENCI  ;
DR   Q7N7Z5, PGK_PHOLL  ;  Q8GF87, PGK_PHOLU  ;  P62418, PGK_PHOPR  ;
DR   Q7ZA46, PGK_PICPA  ;  Q6KYV3, PGK_PICTO  ;  P84731, PGK_PINST  ;
DR   P27362, PGK_PLAF7  ;  Q7MU77, PGK_PORGI  ;  B4S6S2, PGK_PROA2  ;
DR   Q6A9J3, PGK_PROAC  ;  A3PAR3, PGK_PROM0  ;  A2C025, PGK_PROM1  ;
DR   A8G2K1, PGK_PROM2  ;  A2CDG7, PGK_PROM3  ;  A9BDF8, PGK_PROM4  ;
DR   A2BUH2, PGK_PROM5  ;  Q31CY6, PGK_PROM9  ;  Q7VDZ4, PGK_PROMA  ;
DR   B4EUH8, PGK_PROMH  ;  Q7V461, PGK_PROMM  ;  Q7V390, PGK_PROMP  ;
DR   A2BNZ0, PGK_PROMS  ;  Q46HH8, PGK_PROMT  ;  A4SH15, PGK_PROVI  ;
DR   Q48CH7, PGK_PSE14  ;  Q15QK4, PGK_PSEA6  ;  A6UZ15, PGK_PSEA7  ;
DR   B7V4D9, PGK_PSEA8  ;  Q02TL3, PGK_PSEAB  ;  Q9I5Y4, PGK_PSEAE  ;
DR   Q1I3Y0, PGK_PSEE4  ;  Q4K4J1, PGK_PSEF5  ;  C3K3F1, PGK_PSEFS  ;
DR   Q3ILL7, PGK_PSEHT  ;  A4XPG4, PGK_PSEMY  ;  P85949, PGK_PSEMZ  ;
DR   A5W9Z6, PGK_PSEP1  ;  Q3K5F2, PGK_PSEPF  ;  B0KLY7, PGK_PSEPG  ;
DR   Q88D64, PGK_PSEPK  ;  B1J302, PGK_PSEPW  ;  Q88AK3, PGK_PSESM  ;
DR   Q4ZM05, PGK_PSEU2  ;  Q1QCY9, PGK_PSYCK  ;  A5WFD0, PGK_PSYWF  ;
DR   Q9UZW0, PGK_PYRAB  ;  Q8ZWK6, PGK_PYRAE  ;  P61883, PGK_PYRFU  ;
DR   O58965, PGK_PYRHO  ;  Q5JIG7, PGK_PYRKO  ;  P61884, PGK_PYRWO  ;
DR   Q8Y1W6, PGK_RALSO  ;  A9WT63, PGK_RENSM  ;  Q1MC31, PGK_RHIL3  ;
DR   Q98FJ1, PGK_RHILO  ;  B5ZPA0, PGK_RHILW  ;  Q92M79, PGK_RHIME  ;
DR   C3MIJ2, PGK_RHISN  ;  Q7UEX1, PGK_RHOBA  ;  B6IWR7, PGK_RHOCS  ;
DR   C0ZZF3, PGK_RHOE4  ;  Q21S63, PGK_RHOFD  ;  C1B4L7, PGK_RHOOB  ;
DR   P62419, PGK_RHOPA  ;  A3PIU6, PGK_RHOS1  ;  Q3J3I6, PGK_RHOS4  ;
DR   A4WRI4, PGK_RHOS5  ;  B9KQT7, PGK_RHOSK  ;  Q0S0J4, PGK_RHOSR  ;
DR   A7NKY6, PGK_ROSCS  ;  Q164R7, PGK_ROSDO  ;  A5UTB6, PGK_ROSS1  ;
DR   Q1AUH7, PGK_RUBXD  ;  A1AVA8, PGK_RUTMC  ;  A4FBM5, PGK_SACEN  ;
DR   B5F5J4, PGK_SALA4  ;  A8LW18, PGK_SALAI  ;  A9MRF1, PGK_SALAR  ;
DR   Q57K45, PGK_SALCH  ;  B5FUI2, PGK_SALDC  ;  B5QXJ6, PGK_SALEP  ;
DR   B5RE30, PGK_SALG2  ;  B4THF3, PGK_SALHS  ;  B4T5H1, PGK_SALNS  ;
DR   Q5PJI6, PGK_SALPA  ;  A9N3Q5, PGK_SALPB  ;  B5BFN4, PGK_SALPK  ;
DR   Q2S3A7, PGK_SALRD  ;  B4TV38, PGK_SALSV  ;  P65703, PGK_SALTI  ;
DR   A4XDR3, PGK_SALTO  ;  P65702, PGK_SALTY  ;  P41759, PGK_SCHMA  ;
DR   O60101, PGK_SCHPO  ;  A8GIV0, PGK_SERP5  ;  B8E5U4, PGK_SHEB2  ;
DR   A3D0U1, PGK_SHEB5  ;  A6WS76, PGK_SHEB8  ;  A9L1M3, PGK_SHEB9  ;
DR   Q12QA3, PGK_SHEDO  ;  Q087Q6, PGK_SHEFN  ;  B0TUC1, PGK_SHEHH  ;
DR   A3QAX8, PGK_SHELP  ;  Q8EIB1, PGK_SHEON  ;  A8H0N0, PGK_SHEPA  ;
DR   A4Y3S0, PGK_SHEPC  ;  B8CU40, PGK_SHEPW  ;  A0L0K6, PGK_SHESA  ;
DR   A8FRL4, PGK_SHESH  ;  Q0HM62, PGK_SHESM  ;  Q0HRM4, PGK_SHESR  ;
DR   A1RN68, PGK_SHESW  ;  B1KF21, PGK_SHEWM  ;  Q31WI5, PGK_SHIBS  ;
DR   Q32BY6, PGK_SHIDS  ;  Q0T0X4, PGK_SHIF8  ;  P0A7A1, PGK_SHIFL  ;
DR   Q3YXU6, PGK_SHISS  ;  Q5LR94, PGK_SILPO  ;  Q1GHP9, PGK_SILST  ;
DR   A6UCV3, PGK_SINMW  ;  Q2NRD5, PGK_SODGM  ;  Q01Y83, PGK_SOLUE  ;
DR   Q1GTJ0, PGK_SPHAL  ;  A5V9J6, PGK_SPHWW  ;  Q7WTU1, PGK_SPICI  ;
DR   A7WZS6, PGK_STAA1  ;  A6TZQ2, PGK_STAA2  ;  Q2FIM0, PGK_STAA3  ;
DR   Q2G031, PGK_STAA8  ;  A5IQX7, PGK_STAA9  ;  Q2YSF1, PGK_STAAB  ;
DR   Q5HHP4, PGK_STAAC  ;  A6QF82, PGK_STAAE  ;  P68819, PGK_STAAM  ;
DR   P99135, PGK_STAAN  ;  Q6GIL7, PGK_STAAR  ;  Q6GB57, PGK_STAAS  ;
DR   A8Z1A1, PGK_STAAT  ;  P68820, PGK_STAAU  ;  P68821, PGK_STAAW  ;
DR   B9DJJ6, PGK_STACT  ;  Q5HQV3, PGK_STAEQ  ;  Q8CTD6, PGK_STAES  ;
DR   Q4L4K4, PGK_STAHJ  ;  Q49W00, PGK_STAS1  ;  Q3JZB8, PGK_STRA1  ;
DR   Q8E3F0, PGK_STRA3  ;  Q8DXT0, PGK_STRA5  ;  Q829W2, PGK_STRAW  ;
DR   Q9Z519, PGK_STRCO  ;  C0M940, PGK_STRE4  ;  B4U0W3, PGK_STREM  ;
DR   A8AUR9, PGK_STRGC  ;  B1W0Z3, PGK_STRGG  ;  B4STV2, PGK_STRM5  ;
DR   B2FSF3, PGK_STRMK  ;  Q8DVV2, PGK_STRMU  ;  P68897, PGK_STRP1  ;
DR   Q04LZ5, PGK_STRP2  ;  P0DD04, PGK_STRP3  ;  B5E1U9, PGK_STRP4  ;
DR   Q5XA18, PGK_STRP6  ;  C1C5M3, PGK_STRP7  ;  Q8NZG3, PGK_STRP8  ;
DR   Q1J9Y4, PGK_STRPB  ;  Q1JK32, PGK_STRPC  ;  Q1J4X9, PGK_STRPF  ;
DR   A2RCM1, PGK_STRPG  ;  B1IA36, PGK_STRPI  ;  B8ZLX5, PGK_STRPJ  ;
DR   Q48RF9, PGK_STRPM  ;  Q97S89, PGK_STRPN  ;  P0DD05, PGK_STRPQ  ;
DR   B2IMA2, PGK_STRPS  ;  B5XIF1, PGK_STRPZ  ;  Q8DQX8, PGK_STRR6  ;
DR   A4VYY1, PGK_STRS2  ;  C0MF22, PGK_STRS7  ;  A3CKQ4, PGK_STRSV  ;
DR   A4VSN8, PGK_STRSY  ;  Q5LY23, PGK_STRT1  ;  Q8VVB6, PGK_STRT2  ;
DR   Q03IS8, PGK_STRTD  ;  B9DVS0, PGK_STRU0  ;  C1CCP3, PGK_STRZJ  ;
DR   C1CIZ1, PGK_STRZP  ;  C1CQ04, PGK_STRZT  ;  Q4J939, PGK_SULAC  ;
DR   Q30PQ4, PGK_SULDN  ;  P50317, PGK_SULSO  ;  Q971K1, PGK_SULTO  ;
DR   Q67SW6, PGK_SYMTH  ;  Q31P73, PGK_SYNE7  ;  A0LJZ1, PGK_SYNFM  ;
DR   Q2JXF0, PGK_SYNJA  ;  Q2JKX6, PGK_SYNJB  ;  B1XNQ1, PGK_SYNP2  ;
DR   Q5N4Z6, PGK_SYNP6  ;  A5GPB2, PGK_SYNPW  ;  Q7U3V0, PGK_SYNPX  ;
DR   A5GW73, PGK_SYNR3  ;  Q0I6M5, PGK_SYNS3  ;  Q3AVX6, PGK_SYNS9  ;
DR   Q3AGU1, PGK_SYNSC  ;  P74421, PGK_SYNY3  ;  C5BTP7, PGK_TERTT  ;
DR   O00871, PGK_TETPY  ;  P50313, PGK_TETTH  ;  B7IDG7, PGK_THEAB  ;
DR   Q9HJ95, PGK_THEAC  ;  Q8DGP7, PGK_THEEB  ;  A8F5X9, PGK_THELT  ;
DR   A6LMG3, PGK_THEM4  ;  B6YWL5, PGK_THEON  ;  A5IJ98, PGK_THEP1  ;
DR   B9KZ66, PGK_THERP  ;  C6A0Y7, PGK_THESM  ;  B1L8B8, PGK_THESQ  ;
DR   P62420, PGK_THET2  ;  P09403, PGK_THET8  ;  Q8R965, PGK_THETN  ;
DR   Q97BC6, PGK_THEVO  ;  Q3SMD2, PGK_THIDA  ;  B8GP44, PGK_THISH  ;
DR   C4LE53, PGK_TOLAT  ;  P62421, PGK_TREDE  ;  O83549, PGK_TREPA  ;
DR   B2S3D0, PGK_TREPS  ;  Q10Z46, PGK_TRIEI  ;  P14228, PGK_TRIRE  ;
DR   P24590, PGK_TRIVI  ;  Q83HP8, PGK_TROW8  ;  Q83GI2, PGK_TROWT  ;
DR   Q9PQL2, PGK_UREPA  ;  A5CXU9, PGK_VESOH  ;  A5F9G2, PGK_VIBC3  ;
DR   P0C6Q3, PGK_VIBCH  ;  Q5E7Q9, PGK_VIBF1  ;  B5F9T5, PGK_VIBFM  ;
DR   A7MTQ1, PGK_VIBHB  ;  Q87LL1, PGK_VIBPA  ;  Q8DCA0, PGK_VIBVU  ;
DR   Q7MHL1, PGK_VIBVY  ;  Q8D2P9, PGK_WIGBR  ;  P62422, PGK_WOLPM  ;
DR   B3CM25, PGK_WOLPP  ;  Q7M9C1, PGK_WOLSU  ;  Q5GRV2, PGK_WOLTR  ;
DR   C0R4J5, PGK_WOLWR  ;  Q8PHB2, PGK_XANAC  ;  Q3BPW7, PGK_XANC5  ;
DR   Q4UY23, PGK_XANC8  ;  B0RPF1, PGK_XANCB  ;  Q8P5Z4, PGK_XANCP  ;
DR   P50314, PGK_XANFL  ;  Q2P0F7, PGK_XANOM  ;  B2SI21, PGK_XANOP  ;
DR   Q5GXA2, PGK_XANOR  ;  A7IJW3, PGK_XANP2  ;  Q9PF55, PGK_XYLFA  ;
DR   Q87AH8, PGK_XYLFT  ;  P29407, PGK_YARLI  ;  P00560, PGK_YEAST  ;
DR   A1JPR0, PGK_YERE8  ;  A7FF05, PGK_YERP3  ;  Q1CB61, PGK_YERPA  ;
DR   B2K0S0, PGK_YERPB  ;  Q8ZHH3, PGK_YERPE  ;  A9R4J2, PGK_YERPG  ;
DR   Q1CEY3, PGK_YERPN  ;  A4TI90, PGK_YERPP  ;  Q666Q1, PGK_YERPS  ;
DR   B1JNR1, PGK_YERPY  ;  P09404, PGK_ZYMMO  ;
//
ID   2.7.2.4
DE   Aspartate kinase.
AN   Aspartokinase.
CA   ATP + L-aspartate = ADP + 4-phospho-L-aspartate.
CC   -!- The enzyme from Escherichia coli is a multifunctional protein, which
CC       also catalyzes the reaction of EC 1.1.1.3.
PR   PROSITE; PDOC00289;
DR   P00561, AK1H_ECOLI ;  P27725, AK1H_SERMA ;  Q9LYU8, AK1_ARATH  ;
DR   Q04795, AK1_BACSU  ;  P00562, AK2H_ECOLI ;  O23653, AK2_ARATH  ;
DR   Q59229, AK2_BACSG  ;  P08495, AK2_BACSU  ;  P53553, AK2_GEOSE  ;
DR   Q9S702, AK3_ARATH  ;  P94417, AK3_BACSU  ;  P08660, AK3_ECOLI  ;
DR   Q9SA18, AKH1_ARATH ;  P49079, AKH1_MAIZE ;  O81852, AKH2_ARATH ;
DR   P49080, AKH2_MAIZE ;  P57290, AKH_BUCAI  ;  Q8K9U9, AKH_BUCAP  ;
DR   Q89AR4, AKH_BUCBP  ;  P37142, AKH_DAUCA  ;  P44505, AKH_HAEIN  ;
DR   O67221, AK_AQUAE   ;  Q9PK32, AK_CHLMU   ;  Q9Z6L0, AK_CHLPN   ;
DR   O84367, AK_CHLTR   ;  Q8RQN1, AK_COREF   ;  P41398, AK_CORFL   ;
DR   P26512, AK_CORGL   ;  Q9ZJZ7, AK_HELPJ   ;  O25827, AK_HELPY   ;
DR   Q57991, AK_METJA   ;  P0A4Z9, AK_MYCBO   ;  P41403, AK_MYCSM   ;
DR   P0A4Z8, AK_MYCTU   ;  O69077, AK_PSEAE   ;  Q1RGM9, AK_RICBR   ;
DR   Q92GF9, AK_RICCN   ;  Q4UK84, AK_RICFE   ;  Q9ZCI7, AK_RICPR   ;
DR   Q68VZ7, AK_RICTY   ;  O60163, AK_SCHPO   ;  P61488, AK_THET2   ;
DR   P61489, AK_THETH   ;  P10869, AK_YEAST   ;
//
ID   2.7.2.5
DE   Transferred entry: 6.3.4.16.
//
ID   2.7.2.6
DE   Formate kinase.
CA   ATP + formate = ADP + formyl phosphate.
//
ID   2.7.2.7
DE   Butyrate kinase.
CA   ATP + butanoate = ADP + butanoyl phosphate.
CC   -!- The enzyme from Clostridium sp. also acts, more slowly on pentanoate
CC       and propanoate, and on some branched-chain fatty acids (cf.
CC       EC 2.7.1.14).
PR   PROSITE; PDOC00826;
DR   Q45829, BUK1_CLOAB ;  Q9X276, BUK1_THEMA ;  Q8R832, BUK1_THETN ;
DR   Q97II1, BUK2_CLOAB ;  Q9X278, BUK2_THEMA ;  Q8R828, BUK2_THETN ;
DR   C3P7U3, BUK_BACAA  ;  C3LJT8, BUK_BACAC  ;  Q81M67, BUK_BACAN  ;
DR   B7JM15, BUK_BACC0  ;  Q731D0, BUK_BACC1  ;  B7IXF5, BUK_BACC2  ;
DR   C1ERN7, BUK_BACC3  ;  B7HB35, BUK_BACC4  ;  B7HNS7, BUK_BACC7  ;
DR   A7GSI3, BUK_BACCN  ;  B9IXF8, BUK_BACCQ  ;  Q818T1, BUK_BACCR  ;
DR   Q635C1, BUK_BACCZ  ;  Q6HE00, BUK_BACHK  ;  P54532, BUK_BACSU  ;
DR   Q8A4P5, BUK_BACTN  ;  A6KZZ5, BUK_BACV8  ;  A9VGB0, BUK_BACWK  ;
DR   Q05619, BUK_CLOB8  ;  B2UYH0, BUK_CLOBA  ;  B2TIN4, BUK_CLOBB  ;
DR   Q0TMV4, BUK_CLOP1  ;  P81337, BUK_CLOPA  ;  P0C2D8, BUK_CLOPE  ;
DR   Q0SQK0, BUK_CLOPS  ;  Q890U0, BUK_CLOTE  ;  B5Y8N2, BUK_COPPD  ;
DR   Q9RVA9, BUK_DEIRA  ;  C6BVJ0, BUK_DESAD  ;  Q30WM4, BUK_DESDG  ;
DR   B2KEH0, BUK_ELUMP  ;  Q9RPS7, BUK_ENTFA  ;  B1YLR4, BUK_EXIS2  ;
DR   P54621, BUK_GEOSE  ;  Q92BY5, BUK_LISIN  ;  C1L2S6, BUK_LISMC  ;
DR   Q71ZV2, BUK_LISMF  ;  B8DFV8, BUK_LISMH  ;  Q8Y7B6, BUK_LISMO  ;
DR   A0AIH1, BUK_LISW6  ;  Q8CXE5, BUK_OCEIH  ;  A5ILI6, BUK_THEP1  ;
//
ID   2.7.2.8
DE   Acetylglutamate kinase.
CA   ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate.
DR   P78586, ARG56_CANAL;  Q54M18, ARG56_DICDI;  P54898, ARG56_NEUCR;
DR   P31318, ARG56_SCHPO;  Q01217, ARG56_YEAST;  B0CAM3, ARGB_ACAM1 ;
DR   A1TUP2, ARGB_ACIAC ;  Q6FDQ8, ARGB_ACIAD ;  B7GYK7, ARGB_ACIB3 ;
DR   B7I7U4, ARGB_ACIB5 ;  B2HV30, ARGB_ACIBC ;  Q1IIZ0, ARGB_ACIBL ;
DR   B0VTE3, ARGB_ACIBS ;  A3M326, ARGB_ACIBT ;  B0V8Y6, ARGB_ACIBY ;
DR   A0LUC3, ARGB_ACIC1 ;  C1F4F1, ARGB_ACIC5 ;  A5G0G0, ARGB_ACICJ ;
DR   A1W3L0, ARGB_ACISJ ;  A3MYW5, ARGB_ACTP2 ;  B3H084, ARGB_ACTP7 ;
DR   B0BSQ0, ARGB_ACTPJ ;  A6VKY6, ARGB_ACTSZ ;  A0KFV1, ARGB_AERHH ;
DR   Q9YBY9, ARGB_AERPE ;  A4SIM3, ARGB_AERS4 ;  B9J8D8, ARGB_AGRRK ;
DR   Q8UIB7, ARGB_AGRT5 ;  B9JZL3, ARGB_AGRVS ;  B2URE3, ARGB_AKKM8 ;
DR   Q0VT62, ARGB_ALCBS ;  Q0ACJ6, ARGB_ALHEH ;  A6TTJ1, ARGB_ALKMQ ;
DR   B4S0H7, ARGB_ALTMD ;  B8J8V3, ARGB_ANAD2 ;  Q2IMB4, ARGB_ANADE ;
DR   A7H6Q3, ARGB_ANADF ;  B4ULH7, ARGB_ANASK ;  B9MR75, ARGB_ANATD ;
DR   Q3MFQ8, ARGB_ANAVT ;  O67848, ARGB_AQUAE ;  A8EWG2, ARGB_ARCB4 ;
DR   O28988, ARGB_ARCFU ;  Q5P286, ARGB_AROAE ;  A1R587, ARGB_ARTAT ;
DR   B8HGC5, ARGB_ARTCA ;  A0JV22, ARGB_ARTS2 ;  A8IPV3, ARGB_AZOC5 ;
DR   B6YS18, ARGB_AZOPC ;  A1KAK4, ARGB_AZOSB ;  C1DI53, ARGB_AZOVD ;
DR   A7Z3A9, ARGB_BACA2 ;  C3P7R6, ARGB_BACAA ;  C3LJQ7, ARGB_BACAC ;
DR   A0RID0, ARGB_BACAH ;  P68728, ARGB_BACAM ;  Q81M97, ARGB_BACAN ;
DR   B7JLY5, ARGB_BACC0 ;  Q731G5, ARGB_BACC1 ;  B7IWP4, ARGB_BACC2 ;
DR   C1ER04, ARGB_BACC3 ;  B7HB02, ARGB_BACC4 ;  B7HNP7, ARGB_BACC7 ;
DR   A7GSF2, ARGB_BACCN ;  B9IXC7, ARGB_BACCQ ;  Q818W1, ARGB_BACCR ;
DR   Q635F2, ARGB_BACCZ ;  Q5LIQ2, ARGB_BACFN ;  Q64ZT7, ARGB_BACFR ;
DR   Q9K8V4, ARGB_BACHD ;  Q6HE30, ARGB_BACHK ;  Q65LE8, ARGB_BACLD ;
DR   A8FBW1, ARGB_BACP2 ;  Q5WEW9, ARGB_BACSK ;  P68729, ARGB_BACSU ;
DR   Q8A2B0, ARGB_BACTN ;  A6L013, ARGB_BACV8 ;  A9VG70, ARGB_BACWK ;
DR   A1UUC1, ARGB_BARBK ;  Q6G552, ARGB_BARHE ;  Q6G1F7, ARGB_BARQU ;
DR   A9ILI4, ARGB_BART1 ;  C5BW20, ARGB_BEUC1 ;  B8DU56, ARGB_BIFA0 ;
DR   A1A1X1, ARGB_BIFAA ;  B3DSZ1, ARGB_BIFLD ;  P59295, ARGB_BIFLO ;
DR   B7GTP4, ARGB_BIFLS ;  Q2KU83, ARGB_BORA1 ;  Q7WEW1, ARGB_BORBR ;
DR   Q7W3I6, ARGB_BORPA ;  A9I0K4, ARGB_BORPD ;  Q7VSM2, ARGB_BORPE ;
DR   C0QYU9, ARGB_BRAHW ;  Q89BP7, ARGB_BRAJA ;  A5ESP9, ARGB_BRASB ;
DR   A4YLC7, ARGB_BRASO ;  C0Z6T0, ARGB_BREBN ;  B2SC12, ARGB_BRUA1 ;
DR   Q2YJR0, ARGB_BRUA2 ;  Q576T8, ARGB_BRUAB ;  A9MCV1, ARGB_BRUC2 ;
DR   C0RMG5, ARGB_BRUMB ;  Q8YDA5, ARGB_BRUME ;  A5VVT1, ARGB_BRUO2 ;
DR   A9WW36, ARGB_BRUSI ;  P59296, ARGB_BRUSU ;  B8D8K7, ARGB_BUCA5 ;
DR   P57157, ARGB_BUCAI ;  P59098, ARGB_BUCAP ;  B8D6W1, ARGB_BUCAT ;
DR   B1YPR7, ARGB_BURA4 ;  Q1BSM4, ARGB_BURCA ;  B1K0G5, ARGB_BURCC ;
DR   A0KBG7, ARGB_BURCH ;  B4E7Y8, ARGB_BURCJ ;  Q0BAX4, ARGB_BURCM ;
DR   A3MRR8, ARGB_BURM7 ;  A2S874, ARGB_BURM9 ;  Q62F04, ARGB_BURMA ;
DR   A1V7K1, ARGB_BURMS ;  A3NQ57, ARGB_BURP0 ;  Q3JXA9, ARGB_BURP1 ;
DR   A3N4G7, ARGB_BURP6 ;  B2JJX2, ARGB_BURP8 ;  B2T1N4, ARGB_BURPP ;
DR   Q63YI7, ARGB_BURPS ;  Q39BX5, ARGB_BURS3 ;  Q2T281, ARGB_BURTA ;
DR   A4JIR7, ARGB_BURVG ;  Q146X4, ARGB_BURXL ;  A8M8Q8, ARGB_CALMQ ;
DR   A4XJN8, ARGB_CALS8 ;  A7GXW0, ARGB_CAMC5 ;  A0RPV9, ARGB_CAMFF ;
DR   A7I241, ARGB_CAMHC ;  A8FK16, ARGB_CAMJ8 ;  A7H1S5, ARGB_CAMJD ;
DR   Q9PIR8, ARGB_CAMJE ;  A1VXU8, ARGB_CAMJJ ;  Q5HWN6, ARGB_CAMJR ;
DR   Q3A9W2, ARGB_CARHZ ;  B8GYF5, ARGB_CAUCN ;  Q9ABE5, ARGB_CAUCR ;
DR   B0T130, ARGB_CAUSK ;  B3PG71, ARGB_CELJU ;  A0RWW1, ARGB_CENSY ;
DR   A9WKG4, ARGB_CHLAA ;  B8G2Z2, ARGB_CHLAD ;  Q3ASI5, ARGB_CHLCH ;
DR   B3ECN9, ARGB_CHLL2 ;  B3QN94, ARGB_CHLP8 ;  A1BG26, ARGB_CHLPD ;
DR   B9LDR9, ARGB_CHLSY ;  P59297, ARGB_CHLTE ;  Q1QT79, ARGB_CHRSD ;
DR   Q7NR63, ARGB_CHRVO ;  A8AKW3, ARGB_CITK8 ;  A5CSJ6, ARGB_CLAM3 ;
DR   B0RHD2, ARGB_CLAMS ;  Q97GH8, ARGB_CLOAB ;  A6M1Z8, ARGB_CLOB8 ;
DR   Q188A2, ARGB_CLOD6 ;  B9E1X2, ARGB_CLOK1 ;  A5N8G6, ARGB_CLOK5 ;
DR   A0Q1F1, ARGB_CLONN ;  A9KHN3, ARGB_CLOPH ;  A3DGK6, ARGB_CLOTH ;
DR   Q489P5, ARGB_COLP3 ;  Q6NHG8, ARGB_CORDI ;  Q8FTN3, ARGB_COREF ;
DR   A4QDZ0, ARGB_CORGB ;  Q59281, ARGB_CORGL ;  Q4JW02, ARGB_CORJK ;
DR   B1VH34, ARGB_CORU7 ;  Q0KF61, ARGB_CUPNH ;  Q476X1, ARGB_CUPPJ ;
DR   Q9TLT0, ARGB_CYACA ;  Q85FW5, ARGB_CYAME ;  Q11QI8, ARGB_CYTH3 ;
DR   Q47IE5, ARGB_DECAR ;  Q3Z730, ARGB_DEHE1 ;  A5FQ84, ARGB_DEHSB ;
DR   Q3ZYG3, ARGB_DEHSC ;  Q1J2A2, ARGB_DEIGD ;  Q9RRP6, ARGB_DEIRA ;
DR   A9BY30, ARGB_DELAS ;  Q30ZT4, ARGB_DESDG ;  B8FWU9, ARGB_DESHD ;
DR   Q24ZJ1, ARGB_DESHY ;  C4XN27, ARGB_DESMR ;  Q6AR56, ARGB_DESPS ;
DR   A4J169, ARGB_DESRM ;  Q72C18, ARGB_DESVH ;  A1VDW4, ARGB_DESVV ;
DR   A8LM96, ARGB_DINSH ;  A7ZUH7, ARGB_ECO24 ;  B7MI95, ARGB_ECO45 ;
DR   B7LA54, ARGB_ECO55 ;  P0A6C9, ARGB_ECO57 ;  B5Z061, ARGB_ECO5E ;
DR   B7M713, ARGB_ECO8A ;  C5A0Q8, ARGB_ECOBW ;  B1XBC4, ARGB_ECODH ;
DR   A8A767, ARGB_ECOHS ;  A1AID7, ARGB_ECOK1 ;  Q0TAA1, ARGB_ECOL5 ;
DR   P59298, ARGB_ECOL6 ;  B1IVB9, ARGB_ECOLC ;  P0A6C8, ARGB_ECOLI ;
DR   B6I5H5, ARGB_ECOSE ;  Q1R3V2, ARGB_ECOUT ;  C5BC59, ARGB_EDWI9 ;
DR   Q3YS21, ARGB_EHRCJ ;  Q2GGM8, ARGB_EHRCR ;  Q5FGU6, ARGB_EHRRG ;
DR   Q5HB82, ARGB_EHRRW ;  A4WG52, ARGB_ENT38 ;  A7ML88, ARGB_ENTS8 ;
DR   Q6DAR0, ARGB_ERWCT ;  Q2N7E1, ARGB_ERYLH ;  Q0RFA8, ARGB_FRAAA ;
DR   Q2J862, ARGB_FRASC ;  B5ED10, ARGB_GEOBB ;  Q5L1V3, ARGB_GEOKA ;
DR   B3E9Y3, ARGB_GEOLS ;  Q39Z75, ARGB_GEOMG ;  Q07905, ARGB_GEOSE ;
DR   B9M371, ARGB_GEOSF ;  Q74GU4, ARGB_GEOSL ;  C6E6Y1, ARGB_GEOSM ;
DR   C5D766, ARGB_GEOSW ;  A4IL48, ARGB_GEOTN ;  A5GDA1, ARGB_GEOUR ;
DR   Q7NEE9, ARGB_GLOVI ;  A9HKR8, ARGB_GLUDA ;  Q5FPX8, ARGB_GLUOX ;
DR   Q0BU70, ARGB_GRABC ;  Q6B8Z0, ARGB_GRATL ;  Q7VMS6, ARGB_HAEDU ;
DR   Q2SN65, ARGB_HAHCH ;  A1WZE7, ARGB_HALHL ;  B8D1G8, ARGB_HALOH ;
DR   Q7VJR4, ARGB_HELHP ;  B0TCA8, ARGB_HELMI ;  A4G9B1, ARGB_HERAR ;
DR   B4U7A6, ARGB_HYDS0 ;  Q0C545, ARGB_HYPNA ;  A8AA51, ARGB_IGNH4 ;
DR   A6T328, ARGB_JANMA ;  Q28UR2, ARGB_JANSC ;  A6WCT4, ARGB_KINRD ;
DR   B5XZ17, ARGB_KLEP3 ;  A6TGE3, ARGB_KLEP7 ;  C5CHW9, ARGB_KOSOT ;
DR   Q9CHD2, ARGB_LACLA ;  A2RM00, ARGB_LACLM ;  Q030G2, ARGB_LACLS ;
DR   O08320, ARGB_LACPL ;  Q1MRI7, ARGB_LAWIP ;  Q6AGD1, ARGB_LEIXX ;
DR   B0SIF3, ARGB_LEPBA ;  Q04NM9, ARGB_LEPBJ ;  Q04WW3, ARGB_LEPBL ;
DR   Q75FU1, ARGB_LEPIC ;  P59299, ARGB_LEPIN ;  B1MWD1, ARGB_LEUCK ;
DR   Q040B2, ARGB_LEUMM ;  Q92BB9, ARGB_LISIN ;  C1KVN6, ARGB_LISMC ;
DR   Q71Z78, ARGB_LISMF ;  B8DHF2, ARGB_LISMH ;  Q8Y6U3, ARGB_LISMO ;
DR   A0AJ38, ARGB_LISW6 ;  A0LDX4, ARGB_MAGSM ;  Q65W17, ARGB_MANSM ;
DR   A1U6L0, ARGB_MARAV ;  A6VSX6, ARGB_MARMS ;  Q11LE1, ARGB_MESSB ;
DR   A6UT97, ARGB_META3 ;  Q8THJ9, ARGB_METAC ;  A7I4D4, ARGB_METB6 ;
DR   Q46D93, ARGB_METBF ;  Q12ZP8, ARGB_METBU ;  Q603M3, ARGB_METCA ;
DR   Q1GZ15, ARGB_METFK ;  Q2FTZ8, ARGB_METHJ ;  Q60382, ARGB_METJA ;
DR   Q8TUX2, ARGB_METKA ;  A2STZ6, ARGB_METLZ ;  A4G0C7, ARGB_METM5 ;
DR   A9A8M9, ARGB_METM6 ;  A6VI50, ARGB_METM7 ;  Q8PXJ8, ARGB_METMA ;
DR   A3CRT9, ARGB_METMJ ;  Q6M154, ARGB_METMP ;  B8IM39, ARGB_METNO ;
DR   B8GFN4, ARGB_METPE ;  A2SD22, ARGB_METPP ;  A5UK52, ARGB_METS3 ;
DR   B0UA74, ARGB_METS4 ;  A4YD40, ARGB_METS5 ;  Q2NGV4, ARGB_METST ;
DR   O26285, ARGB_METTH ;  A0B9X4, ARGB_METTP ;  A6UR56, ARGB_METVS ;
DR   B0JHB1, ARGB_MICAN ;  Q2RG64, ARGB_MOOTA ;  Q9K4Z0, ARGB_MORAB ;
DR   Q9K4Z5, ARGB_MORPR ;  A0QHB2, ARGB_MYCA1 ;  P0A4Y7, ARGB_MYCBO ;
DR   A1KJ71, ARGB_MYCBP ;  C1ANS7, ARGB_MYCBT ;  A4T9V7, ARGB_MYCGI ;
DR   Q9CC13, ARGB_MYCLE ;  B2HR28, ARGB_MYCMM ;  Q740I7, ARGB_MYCPA ;
DR   A0QYT0, ARGB_MYCS2 ;  A3Q0T7, ARGB_MYCSJ ;  A1UHA0, ARGB_MYCSK ;
DR   Q1B7Q7, ARGB_MYCSS ;  A5U311, ARGB_MYCTA ;  P0A4Y6, ARGB_MYCTU ;
DR   A0PP75, ARGB_MYCUA ;  A1TAB0, ARGB_MYCVP ;  Q1D264, ARGB_MYXXD ;
DR   B9L987, ARGB_NAUPA ;  Q5F8D8, ARGB_NEIG1 ;  B4RLF4, ARGB_NEIG2 ;
DR   A9LYZ5, ARGB_NEIM0 ;  Q9JUK2, ARGB_NEIMA ;  Q9JZF7, ARGB_NEIMB ;
DR   A1KTW0, ARGB_NEIMF ;  Q0ADI4, ARGB_NITEC ;  Q820N1, ARGB_NITEU ;
DR   Q1QH71, ARGB_NITHX ;  A9A1K7, ARGB_NITMS ;  Q2YA02, ARGB_NITMU ;
DR   Q3J6V9, ARGB_NITOC ;  A6Q3U3, ARGB_NITSB ;  Q3SN22, ARGB_NITWN ;
DR   Q5YYF7, ARGB_NOCFA ;  A1SJI9, ARGB_NOCSJ ;  B2IX33, ARGB_NOSP7 ;
DR   Q8YXG8, ARGB_NOSS1 ;  Q2G341, ARGB_NOVAD ;  Q8CUN0, ARGB_OCEIH ;
DR   A6WYM1, ARGB_OCHA4 ;  B6JJP1, ARGB_OLICO ;  B1ZUD7, ARGB_OPITP ;
DR   A6L9A0, ARGB_PARD8 ;  A1B0E7, ARGB_PARDP ;  A7HPT7, ARGB_PARL1 ;
DR   P57908, ARGB_PASMU ;  C6DI80, ARGB_PECCP ;  Q3A1V5, ARGB_PELCD ;
DR   Q3B422, ARGB_PELLD ;  B4S9U8, ARGB_PELPB ;  A1ATU7, ARGB_PELPD ;
DR   A5D506, ARGB_PELTS ;  Q4FNF2, ARGB_PELUB ;  C0QRI8, ARGB_PERMH ;
DR   A9BI99, ARGB_PETMO ;  Q7MYD7, ARGB_PHOLL ;  Q6LVG9, ARGB_PHOPR ;
DR   A1VSZ8, ARGB_POLNA ;  B1XSJ0, ARGB_POLNS ;  Q125B6, ARGB_POLSJ ;
DR   A4T0G0, ARGB_POLSQ ;  P69365, ARGB_PORPU ;  P69366, ARGB_PORUM ;
DR   Q1XDF8, ARGB_PORYE ;  Q6A814, ARGB_PROAC ;  A3PBM4, ARGB_PROM0 ;
DR   A2C0V9, ARGB_PROM1 ;  A8G3L5, ARGB_PROM2 ;  A2C7M5, ARGB_PROM3 ;
DR   A2BVG1, ARGB_PROM5 ;  Q31C34, ARGB_PROM9 ;  Q7VD84, ARGB_PROMA ;
DR   B4F1G7, ARGB_PROMH ;  Q7TUU2, ARGB_PROMM ;  Q7TUD1, ARGB_PROMP ;
DR   A2BPY1, ARGB_PROMS ;  Q46GS3, ARGB_PROMT ;  A4SEI5, ARGB_PROVI ;
DR   Q48Q08, ARGB_PSE14 ;  A6VED0, ARGB_PSEA7 ;  B7V5L4, ARGB_PSEA8 ;
DR   Q02E39, ARGB_PSEAB ;  Q9HTN2, ARGB_PSEAE ;  Q1I2T9, ARGB_PSEE4 ;
DR   Q4K3S0, ARGB_PSEF5 ;  C3K475, ARGB_PSEFS ;  A4Y0L1, ARGB_PSEMY ;
DR   A5WB06, ARGB_PSEP1 ;  Q3K4M4, ARGB_PSEPF ;  B0KQ91, ARGB_PSEPG ;
DR   P59300, ARGB_PSEPK ;  B1J4L7, ARGB_PSEPW ;  Q88BD5, ARGB_PSESM ;
DR   Q4ZZY1, ARGB_PSEU2 ;  A4VGS4, ARGB_PSEU5 ;  Q4FU68, ARGB_PSYA2 ;
DR   Q1QDA2, ARGB_PSYCK ;  A1SRI1, ARGB_PSYIN ;  A5WGH7, ARGB_PSYWF ;
DR   Q9V1I5, ARGB_PYRAB ;  Q8ZU99, ARGB_PYRAE ;  A4WJI0, ARGB_PYRAR ;
DR   A3MT40, ARGB_PYRCJ ;  Q8U0B5, ARGB_PYRFU ;  O59398, ARGB_PYRHO ;
DR   A1RR74, ARGB_PYRIL ;  Q1LS50, ARGB_RALME ;  Q8Y3E7, ARGB_RALSO ;
DR   A9WQ86, ARGB_RENSM ;  B3Q031, ARGB_RHIE6 ;  Q2KD36, ARGB_RHIEC ;
DR   Q1MM66, ARGB_RHIL3 ;  Q98D76, ARGB_RHILO ;  B5ZN33, ARGB_RHILW ;
DR   Q92SG0, ARGB_RHIME ;  C3MF41, ARGB_RHISN ;  Q7UQZ8, ARGB_RHOBA ;
DR   B6IPH3, ARGB_RHOCS ;  Q21SM4, ARGB_RHOFD ;  Q2J2B9, ARGB_RHOP2 ;
DR   Q07TX9, ARGB_RHOP5 ;  Q6NC44, ARGB_RHOPA ;  Q21B51, ARGB_RHOPB ;
DR   Q13F27, ARGB_RHOPS ;  B3QCH9, ARGB_RHOPT ;  Q2RP10, ARGB_RHORT ;
DR   A3PNB5, ARGB_RHOS1 ;  Q3IYY2, ARGB_RHOS4 ;  A4WWI7, ARGB_RHOS5 ;
DR   B9KP00, ARGB_RHOSK ;  Q0SI54, ARGB_RHOSR ;  A7NPB5, ARGB_ROSCS ;
DR   Q16AA4, ARGB_ROSDO ;  A5V0J4, ARGB_ROSS1 ;  Q1AS30, ARGB_RUBXD ;
DR   A1AVQ7, ARGB_RUTMC ;  Q21EE9, ARGB_SACD2 ;  A4FKC5, ARGB_SACEN ;
DR   B5F0U8, ARGB_SALA4 ;  A8LY51, ARGB_SALAI ;  A9MI11, ARGB_SALAR ;
DR   Q57H94, ARGB_SALCH ;  B5FPX4, ARGB_SALDC ;  B5QXQ4, ARGB_SALEP ;
DR   B5RF46, ARGB_SALG2 ;  B4TCQ5, ARGB_SALHS ;  B4T0X0, ARGB_SALNS ;
DR   Q5PK74, ARGB_SALPA ;  A9N0G9, ARGB_SALPB ;  C0Q475, ARGB_SALPC ;
DR   B5BJN3, ARGB_SALPK ;  B4TQH5, ARGB_SALSV ;  P63558, ARGB_SALTI ;
DR   A4X652, ARGB_SALTO ;  P63557, ARGB_SALTY ;  A8GL83, ARGB_SERP5 ;
DR   A1S262, ARGB_SHEAM ;  B8EBG2, ARGB_SHEB2 ;  A3DA25, ARGB_SHEB5 ;
DR   A6WTS2, ARGB_SHEB8 ;  A9KTY9, ARGB_SHEB9 ;  Q12SM9, ARGB_SHEDO ;
DR   B0TL87, ARGB_SHEHH ;  A3Q9C7, ARGB_SHELP ;  P59301, ARGB_SHEON ;
DR   A8GZ19, ARGB_SHEPA ;  A4YBU1, ARGB_SHEPC ;  A0L253, ARGB_SHESA ;
DR   A8G1A6, ARGB_SHESH ;  Q0HDU6, ARGB_SHESM ;  Q0I063, ARGB_SHESR ;
DR   A1RPR8, ARGB_SHESW ;  B2TWF4, ARGB_SHIB3 ;  Q31U29, ARGB_SHIBS ;
DR   Q32AB6, ARGB_SHIDS ;  Q0SY35, ARGB_SHIF8 ;  P59302, ARGB_SHIFL ;
DR   Q3YV17, ARGB_SHISS ;  Q5LW17, ARGB_SILPO ;  Q1GJY2, ARGB_SILST ;
DR   A6U5K5, ARGB_SINMW ;  Q2NQZ0, ARGB_SODGM ;  Q02B43, ARGB_SOLUE ;
DR   A9GQU6, ARGB_SORC5 ;  Q1GNH3, ARGB_SPHAL ;  A5VAE6, ARGB_SPHWW ;
DR   A7WXH2, ARGB_STAA1 ;  A6TXW6, ARGB_STAA2 ;  Q2FK80, ARGB_STAA3 ;
DR   Q2G1H6, ARGB_STAA8 ;  A5IP51, ARGB_STAA9 ;  Q2YUZ7, ARGB_STAAB ;
DR   Q5HJJ1, ARGB_STAAC ;  A6QDG6, ARGB_STAAE ;  P63559, ARGB_STAAM ;
DR   P63560, ARGB_STAAN ;  Q6GKC4, ARGB_STAAR ;  Q6GCU4, ARGB_STAAS ;
DR   A8YZA3, ARGB_STAAT ;  P63561, ARGB_STAAW ;  Q5HP23, ARGB_STAEQ ;
DR   Q8CSG0, ARGB_STAES ;  Q4A0M9, ARGB_STAS1 ;  Q828A4, ARGB_STRAW ;
DR   Q9LCS6, ARGB_STRCL ;  Q9L1A3, ARGB_STRCO ;  A8AYI5, ARGB_STRGC ;
DR   B1W3A9, ARGB_STRGG ;  Q8DV44, ARGB_STRMU ;  A3CLY6, ARGB_STRSV ;
DR   Q4JAQ2, ARGB_SULAC ;  Q30S99, ARGB_SULDN ;  C3MZY8, ARGB_SULIA ;
DR   C4KJ29, ARGB_SULIK ;  C3MJ49, ARGB_SULIL ;  C3MYU1, ARGB_SULIM ;
DR   C3NF41, ARGB_SULIN ;  C3N871, ARGB_SULIY ;  A6QAR9, ARGB_SULNB ;
DR   Q980X0, ARGB_SULSO ;  B2V7Y5, ARGB_SULSY ;  Q976J6, ARGB_SULTO ;
DR   Q67KD3, ARGB_SYMTH ;  Q2LT95, ARGB_SYNAS ;  Q6V1L5, ARGB_SYNE7 ;
DR   A0LEB5, ARGB_SYNFM ;  Q2JXF5, ARGB_SYNJA ;  Q2JHF7, ARGB_SYNJB ;
DR   Q5MZ48, ARGB_SYNP6 ;  A5GJC5, ARGB_SYNPW ;  Q7U5C7, ARGB_SYNPX ;
DR   A5GSD0, ARGB_SYNR3 ;  Q0I8J0, ARGB_SYNS3 ;  Q3AWR0, ARGB_SYNS9 ;
DR   Q3ALS4, ARGB_SYNSC ;  Q0AUM4, ARGB_SYNWW ;  P73326, ARGB_SYNY3 ;
DR   P59303, ARGB_THEEB ;  Q47N81, ARGB_THEFY ;  A8F450, ARGB_THELT ;
DR   Q9X2A4, ARGB_THEMA ;  B9K8S3, ARGB_THENN ;  B1YB53, ARGB_THENV ;
DR   A5ILL5, ARGB_THEP1 ;  B0KBW1, ARGB_THEP3 ;  B0K4D4, ARGB_THEPX ;
DR   B1LAP0, ARGB_THESQ ;  Q5SGY0, ARGB_THET8 ;  Q8R7C0, ARGB_THETN ;
DR   Q31ED4, ARGB_THICR ;  Q3SFH1, ARGB_THIDA ;  Q116Q9, ARGB_TRIEI ;
DR   Q0W0P5, ARGB_UNCMA ;  B1H0L5, ARGB_UNCTG ;  A1WH89, ARGB_VEREI ;
DR   A5CXF1, ARGB_VESOH ;  A5F4Z5, ARGB_VIBC3 ;  Q9KNT7, ARGB_VIBCH ;
DR   C3LRV4, ARGB_VIBCM ;  Q5E2E6, ARGB_VIBF1 ;  B5FBP5, ARGB_VIBFM ;
DR   A7MXC0, ARGB_VIBHB ;  Q87L56, ARGB_VIBPA ;  P59304, ARGB_VIBVU ;
DR   Q7MH71, ARGB_VIBVY ;  Q7M7Q9, ARGB_WOLSU ;  Q8PK29, ARGB_XANAC ;
DR   Q8P8J6, ARGB_XANCP ;  Q9PEM7, ARGB_XYLFA ;  Q87EL2, ARGB_XYLFT ;
DR   A1JI23, ARGB_YERE8 ;  A7FD00, ARGB_YERP3 ;  Q1CBV5, ARGB_YERPA ;
DR   B2JZE3, ARGB_YERPB ;  Q8ZA87, ARGB_YERPE ;  A9R515, ARGB_YERPG ;
DR   Q1CNQ4, ARGB_YERPN ;  A4TRH4, ARGB_YERPP ;  Q66G71, ARGB_YERPS ;
DR   B1JQ60, ARGB_YERPY ;  Q5NME2, ARGB_ZYMMO ;  Q9SCL7, NAGK_ARATH ;
//
ID   2.7.2.9
DE   Transferred entry: 6.3.5.5.
//
ID   2.7.2.10
DE   Phosphoglycerate kinase (GTP).
CA   GTP + 3-phospho-D-glycerate = GDP + 3-phospho-D-glyceroyl phosphate.
//
ID   2.7.2.11
DE   Glutamate 5-kinase.
AN   Gamma-glutamyl kinase.
CA   ATP + L-glutamate = ADP + L-glutamate 5-phosphate.
CC   -!- The product rapidly cyclizes to 5-oxoproline and phosphate.
PR   PROSITE; PDOC00701;
DR   P54889, ALH13_CAEEL;  P54887, P5CS1_ARATH;  P54888, P5CS2_ARATH;
DR   O04015, P5CS_ACTDE ;  P54886, P5CS_HUMAN ;  O65361, P5CS_MESCR ;
DR   Q9Z110, P5CS_MOUSE ;  O04226, P5CS_ORYSJ ;  Q5R4M8, P5CS_PONAB ;
DR   Q96480, P5CS_SOLLC ;  P32296, P5CS_VIGAC ;  Q65KU8, PROB1_BACLD;
DR   Q3IEY8, PROB1_PSEHT;  Q98EZ4, PROB1_RHILO;  Q92LB3, PROB1_RHIME;
DR   Q65IS8, PROB2_BACLD;  Q3IHK8, PROB2_PSEHT;  Q989S7, PROB2_RHILO;
DR   Q92LF7, PROB2_RHIME;  B0C1B5, PROB_ACAM1 ;  A1TTD2, PROB_ACIAC ;
DR   Q6F9D9, PROB_ACIAD ;  B7GYV2, PROB_ACIB3 ;  B7I556, PROB_ACIB5 ;
DR   B2HWM8, PROB_ACIBC ;  B0VTQ2, PROB_ACIBS ;  A3M7M1, PROB_ACIBT ;
DR   B0VCR6, PROB_ACIBY ;  B9MDZ8, PROB_ACIET ;  A1W4B1, PROB_ACISJ ;
DR   B9JER2, PROB_AGRRK ;  Q8UBS0, PROB_AGRT5 ;  B9JUH8, PROB_AGRVS ;
DR   Q0VSE5, PROB_ALCBS ;  B6EIF1, PROB_ALISL ;  A6TU99, PROB_ALKMQ ;
DR   A8MFQ6, PROB_ALKOO ;  Q2IMF3, PROB_ANADE ;  Q3M6H4, PROB_ANAVT ;
DR   O67209, PROB_AQUAE ;  Q5P7Z3, PROB_AROAE ;  A1KAD1, PROB_AZOSB ;
DR   Q81P26, PROB_BACAN ;  Q735X2, PROB_BACC1 ;  B7ILK2, PROB_BACC2 ;
DR   B7H674, PROB_BACC4 ;  B9J499, PROB_BACCQ ;  Q81C10, PROB_BACCR ;
DR   Q639W8, PROB_BACCZ ;  Q9KCR4, PROB_BACHD ;  Q6HHC1, PROB_BACHK ;
DR   Q5WH53, PROB_BACSK ;  P39820, PROB_BACSU ;  Q8A1E7, PROB_BACTN ;
DR   A9VK32, PROB_BACWK ;  Q6G4Z1, PROB_BARHE ;  Q6G0S7, PROB_BARQU ;
DR   B8DVU2, PROB_BIFA0 ;  A0ZZZ1, PROB_BIFAA ;  B3DPS5, PROB_BIFLD ;
DR   Q8G4T9, PROB_BIFLO ;  B7GNK0, PROB_BIFLS ;  Q2L067, PROB_BORA1 ;
DR   Q7WQL9, PROB_BORBR ;  Q7W1P3, PROB_BORPA ;  A9IFG1, PROB_BORPD ;
DR   Q7VZX7, PROB_BORPE ;  Q89X86, PROB_BRAJA ;  A5E964, PROB_BRASB ;
DR   B2S805, PROB_BRUA1 ;  Q2YLM3, PROB_BRUA2 ;  Q57B46, PROB_BRUAB ;
DR   A9M881, PROB_BRUC2 ;  C0RF93, PROB_BRUMB ;  P65790, PROB_BRUME ;
DR   A5VSI4, PROB_BRUO2 ;  A9WWW8, PROB_BRUSI ;  P65791, PROB_BRUSU ;
DR   B1YSU8, PROB_BURA4 ;  Q1BZD9, PROB_BURCA ;  B1JVA2, PROB_BURCC ;
DR   A0K4B1, PROB_BURCH ;  B4E5W9, PROB_BURCJ ;  Q0BIH7, PROB_BURCM ;
DR   A9AI59, PROB_BURM1 ;  A3MR91, PROB_BURM7 ;  A2S5R7, PROB_BURM9 ;
DR   Q62GV5, PROB_BURMA ;  A1V0P0, PROB_BURMS ;  Q3JNG1, PROB_BURP1 ;
DR   A3NDS6, PROB_BURP6 ;  B2JHD6, PROB_BURP8 ;  B2SYV1, PROB_BURPP ;
DR   Q63QM1, PROB_BURPS ;  Q39JU6, PROB_BURS3 ;  Q2SZF9, PROB_BURTA ;
DR   A4JBB9, PROB_BURVG ;  Q13U16, PROB_BURXL ;  A8FJQ2, PROB_CAMJ8 ;
DR   Q9PJ29, PROB_CAMJE ;  Q3AF41, PROB_CARHZ ;  B8GYI6, PROB_CAUCN ;
DR   Q9ABB6, PROB_CAUCR ;  Q8KCG4, PROB_CHLTE ;  Q1R0B9, PROB_CHRSD ;
DR   Q7NQC8, PROB_CHRVO ;  A8AKP5, PROB_CITK8 ;  A5CR33, PROB_CLAM3 ;
DR   B0RDG2, PROB_CLAMS ;  Q97E63, PROB_CLOAB ;  A0PXA5, PROB_CLONN ;
DR   Q8XHA6, PROB_CLOPE ;  Q896G3, PROB_CLOTE ;  Q6NFV9, PROB_CORDI ;
DR   Q8FN82, PROB_COREF ;  P0C1E2, PROB_CORGL ;  Q4JWT5, PROB_CORJK ;
DR   P0C1E3, PROB_CORML ;  Q0K6P7, PROB_CUPNH ;  Q46X18, PROB_CUPPJ ;
DR   B3R897, PROB_CUPTR ;  B8HQP9, PROB_CYAP4 ;  B7KGB7, PROB_CYAP7 ;
DR   B7JZW9, PROB_CYAP8 ;  Q47AC9, PROB_DECAR ;  Q3Z705, PROB_DEHE1 ;
DR   A5FQ55, PROB_DEHSB ;  Q3ZYI5, PROB_DEHSC ;  Q1IZP2, PROB_DEIGD ;
DR   Q9RTD8, PROB_DEIRA ;  A9BP67, PROB_DELAS ;  C6BZ93, PROB_DESAD ;
DR   Q30XW1, PROB_DESDG ;  Q24XR7, PROB_DESHY ;  Q6AK08, PROB_DESPS ;
DR   Q72DJ9, PROB_DESVH ;  A1VF55, PROB_DESVV ;  B5YDE1, PROB_DICT6 ;
DR   B8E032, PROB_DICTD ;  A8LK10, PROB_DINSH ;  A7ZI01, PROB_ECO24 ;
DR   B7UJD0, PROB_ECO27 ;  B7MC92, PROB_ECO45 ;  B7L3Z4, PROB_ECO55 ;
DR   P0A7B7, PROB_ECO57 ;  B5Z1I6, PROB_ECO5E ;  B7NK83, PROB_ECO7I ;
DR   B7MQ78, PROB_ECO81 ;  B7M271, PROB_ECO8A ;  C4ZT99, PROB_ECOBW ;
DR   B1XDY5, PROB_ECODH ;  A7ZWK5, PROB_ECOHS ;  A1A7V3, PROB_ECOK1 ;
DR   Q0TL74, PROB_ECOL5 ;  P0A7B6, PROB_ECOL6 ;  B1J0Z2, PROB_ECOLC ;
DR   P0A7B5, PROB_ECOLI ;  B7N8H3, PROB_ECOLU ;  B6I022, PROB_ECOSE ;
DR   B1LHT8, PROB_ECOSM ;  Q1RFS8, PROB_ECOUT ;  A4W6X4, PROB_ENT38 ;
DR   Q839W2, PROB_ENTFA ;  A7MI52, PROB_ENTS8 ;  Q6D1I3, PROB_ERWCT ;
DR   B2VHM7, PROB_ERWT9 ;  B7LNF8, PROB_ESCF3 ;  Q2JDP1, PROB_FRASC ;
DR   B5EEI5, PROB_GEOBB ;  Q5KYA3, PROB_GEOKA ;  B3E610, PROB_GEOLS ;
DR   Q39QR3, PROB_GEOMG ;  B9M0D5, PROB_GEOSF ;  Q747Q3, PROB_GEOSL ;
DR   C6E7M0, PROB_GEOSM ;  C5D2V1, PROB_GEOSW ;  A4IPN3, PROB_GEOTN ;
DR   Q7NPI6, PROB_GLOVI ;  Q5FUL1, PROB_GLUOX ;  Q4QM08, PROB_HAEI8 ;
DR   A5UDH4, PROB_HAEIE ;  A5UI44, PROB_HAEIG ;  P43763, PROB_HAEIN ;
DR   Q2S9T4, PROB_HAHCH ;  A1WY47, PROB_HALHL ;  Q7VJ31, PROB_HELHP ;
DR   A9B6X5, PROB_HERA2 ;  A4G8R3, PROB_HERAR ;  Q5QY57, PROB_IDILO ;
DR   A6T2D4, PROB_JANMA ;  Q28Q11, PROB_JANSC ;  B5Y168, PROB_KLEP3 ;
DR   A6T562, PROB_KLEP7 ;  C5CE10, PROB_KOSOT ;  Q9CF72, PROB_LACLA ;
DR   Q02XV9, PROB_LACLS ;  Q890J5, PROB_LACPL ;  Q1WRR5, PROB_LACS1 ;
DR   C1D9T9, PROB_LARHH ;  Q6AFY0, PROB_LEIXX ;  B1Y279, PROB_LEPCP ;
DR   Q72NQ8, PROB_LEPIC ;  P94871, PROB_LEPIN ;  Q92CE4, PROB_LISIN ;
DR   C1L2G8, PROB_LISMC ;  Q720G2, PROB_LISMF ;  B8DHP2, PROB_LISMH ;
DR   Q93Q56, PROB_LISMO ;  A0AI65, PROB_LISW6 ;  Q2VZU1, PROB_MAGSA ;
DR   Q65RE1, PROB_MANSM ;  A6W351, PROB_MARMS ;  Q9ZG98, PROB_MEIRU ;
DR   Q11CP7, PROB_MESSB ;  Q9HHA0, PROB_METAC ;  Q46F79, PROB_METBF ;
DR   Q12TG0, PROB_METBU ;  Q605N1, PROB_METCA ;  Q1GZ54, PROB_METFK ;
DR   Q8PYP3, PROB_METMA ;  A2SD37, PROB_METPP ;  B0JFY2, PROB_MICAN ;
DR   Q2RKZ7, PROB_MOOTA ;  A0QDH1, PROB_MYCA1 ;  P59958, PROB_MYCBO ;
DR   A1KLD5, PROB_MYCBP ;  C1AEQ6, PROB_MYCBT ;  A4T2J5, PROB_MYCGI ;
DR   B8ZRN2, PROB_MYCLB ;  Q9CBZ5, PROB_MYCLE ;  B2HMG0, PROB_MYCMM ;
DR   Q73XP6, PROB_MYCPA ;  A0R148, PROB_MYCS2 ;  A5U5D5, PROB_MYCTA ;
DR   P71910, PROB_MYCTU ;  A0PU14, PROB_MYCUA ;  A1TC20, PROB_MYCVP ;
DR   Q1DCK9, PROB_MYXXD ;  Q3IP73, PROB_NATPD ;  B4RLE8, PROB_NEIG2 ;
DR   Q9JUK7, PROB_NEIMA ;  Q9JZG2, PROB_NEIMB ;  A1KTV5, PROB_NEIMF ;
DR   Q0AHG4, PROB_NITEC ;  Q820M4, PROB_NITEU ;  Q1QQT9, PROB_NITHX ;
DR   Q2Y7Y3, PROB_NITMU ;  Q3J6R9, PROB_NITOC ;  Q3SVI1, PROB_NITWN ;
DR   Q5Z040, PROB_NOCFA ;  B2J5U5, PROB_NOSP7 ;  Q8YSI2, PROB_NOSS1 ;
DR   Q2G982, PROB_NOVAD ;  Q8CUQ5, PROB_OCEIH ;  A6WXS1, PROB_OCHA4 ;
DR   Q04FB3, PROB_OENOB ;  B6JD20, PROB_OLICO ;  A1B9C7, PROB_PARDP ;
DR   Q9CJU5, PROB_PASMU ;  C6DCX5, PROB_PECCP ;  Q3A1D9, PROB_PELCD ;
DR   A1AT80, PROB_PELPD ;  Q4FP45, PROB_PELUB ;  B4RD63, PROB_PHEZH ;
DR   Q7N7B2, PROB_PHOLL ;  Q6LTX3, PROB_PHOPR ;  A1VK89, PROB_POLNA ;
DR   Q12FA0, PROB_POLSJ ;  Q6A9H7, PROB_PROAC ;  A3PCJ7, PROB_PROM0 ;
DR   A8G4G7, PROB_PROM2 ;  A9BAP2, PROB_PROM4 ;  Q31B89, PROB_PROM9 ;
DR   Q7VC78, PROB_PROMA ;  B4EUV0, PROB_PROMH ;  Q7V844, PROB_PROMM ;
DR   Q7V1R7, PROB_PROMP ;  A2BQS5, PROB_PROMS ;  Q46LE0, PROB_PROMT ;
DR   Q48NL1, PROB_PSE14 ;  A6VBV2, PROB_PSEA7 ;  B7V0A8, PROB_PSEA8 ;
DR   Q02GB2, PROB_PSEAB ;  Q9HVL9, PROB_PSEAE ;  Q1IF12, PROB_PSEE4 ;
DR   Q4K5T9, PROB_PSEF5 ;  A4XYL1, PROB_PSEMY ;  A5VYC7, PROB_PSEP1 ;
DR   Q3K6L0, PROB_PSEPF ;  B0KMF7, PROB_PSEPG ;  Q88Q07, PROB_PSEPK ;
DR   B1JF56, PROB_PSEPW ;  Q889F0, PROB_PSESM ;  Q4ZYK0, PROB_PSEU2 ;
DR   A4VI55, PROB_PSEU5 ;  Q4FRK7, PROB_PSYA2 ;  Q1QA44, PROB_PSYCK ;
DR   Q1LIQ1, PROB_RALME ;  B2UCV2, PROB_RALPJ ;  Q8XVL1, PROB_RALSO ;
DR   B3PRZ4, PROB_RHIE6 ;  Q2K2X5, PROB_RHIEC ;  Q1MA75, PROB_RHIL3 ;
DR   B5ZUE4, PROB_RHILW ;  C3M9Y0, PROB_RHISN ;  Q7UJA8, PROB_RHOBA ;
DR   Q21YZ8, PROB_RHOFD ;  C1AVJ9, PROB_RHOOB ;  Q2J3J7, PROB_RHOP2 ;
DR   Q07U76, PROB_RHOP5 ;  Q6NDE5, PROB_RHOPA ;  Q21D03, PROB_RHOPB ;
DR   Q13DM7, PROB_RHOPS ;  B3Q732, PROB_RHOPT ;  Q2RV05, PROB_RHORT ;
DR   Q3IXX8, PROB_RHOS4 ;  Q0SH52, PROB_RHOSR ;  Q165Y7, PROB_ROSDO ;
DR   Q21M06, PROB_SACD2 ;  B5EWK5, PROB_SALA4 ;  A8M065, PROB_SALAI ;
DR   A9MNR5, PROB_SALAR ;  Q57ST3, PROB_SALCH ;  B5FJX4, PROB_SALDC ;
DR   B5R4S5, PROB_SALEP ;  B5R5R8, PROB_SALG2 ;  B4T7Q5, PROB_SALHS ;
DR   B4SVW5, PROB_SALNS ;  Q5PF68, PROB_SALPA ;  A9MY03, PROB_SALPB ;
DR   B5BDP8, PROB_SALPK ;  Q2S355, PROB_SALRD ;  B4TZ90, PROB_SALSV ;
DR   P65793, PROB_SALTI ;  P65792, PROB_SALTY ;  O13810, PROB_SCHPO ;
DR   P17856, PROB_SERMA ;  A8GAD3, PROB_SERP5 ;  A1S8L2, PROB_SHEAM ;
DR   B0TQC5, PROB_SHEHH ;  Q8EHU2, PROB_SHEON ;  A8H765, PROB_SHEPA ;
DR   A8FYU7, PROB_SHESH ;  B1KD28, PROB_SHEWM ;  B2U3T3, PROB_SHIB3 ;
DR   Q325P4, PROB_SHIBS ;  Q32J26, PROB_SHIDS ;  Q0T7R5, PROB_SHIF8 ;
DR   Q7UDL2, PROB_SHIFL ;  Q3Z595, PROB_SHISS ;  Q5LRY5, PROB_SILPO ;
DR   Q1GHC9, PROB_SILST ;  A6UDV7, PROB_SINMW ;  Q2NVF0, PROB_SODGM ;
DR   Q1GQZ4, PROB_SPHAL ;  Q3K396, PROB_STRA1 ;  P65794, PROB_STRA3 ;
DR   P65795, PROB_STRA5 ;  Q82C83, PROB_STRAW ;  Q9RDJ9, PROB_STRCO ;
DR   C0M7B1, PROB_STRE4 ;  B4U4K7, PROB_STREM ;  A8AX76, PROB_STRGC ;
DR   Q8DVN0, PROB_STRMU ;  Q99YJ7, PROB_STRP1 ;  Q04KZ3, PROB_STRP2 ;
DR   P0DD22, PROB_STRP3 ;  Q5XAK9, PROB_STRP6 ;  C1C6R3, PROB_STRP7 ;
DR   Q8NZX8, PROB_STRP8 ;  Q1JAG2, PROB_STRPB ;  Q1JKL3, PROB_STRPC ;
DR   Q1JFK5, PROB_STRPD ;  Q1J5F5, PROB_STRPF ;  B1IB99, PROB_STRPI ;
DR   B8ZP34, PROB_STRPJ ;  Q48RY6, PROB_STRPM ;  Q97R95, PROB_STRPN ;
DR   P0DD23, PROB_STRPQ ;  B5XML6, PROB_STRPZ ;  Q8DQ61, PROB_STRR6 ;
DR   A4W027, PROB_STRS2 ;  C0MGV5, PROB_STRS7 ;  A3CMT0, PROB_STRSV ;
DR   A4VTT4, PROB_STRSY ;  Q5LY83, PROB_STRT1 ;  Q5M2U0, PROB_STRT2 ;
DR   Q03J02, PROB_STRTD ;  P96488, PROB_STRTR ;  B9DV80, PROB_STRU0 ;
DR   C1CDS8, PROB_STRZJ ;  C1CK17, PROB_STRZP ;  C1CRW2, PROB_STRZT ;
DR   A6QB69, PROB_SULNB ;  Q67LC1, PROB_SYMTH ;  Q2LR78, PROB_SYNAS ;
DR   Q31L42, PROB_SYNE7 ;  Q2JSQ2, PROB_SYNJA ;  Q2JNZ0, PROB_SYNJB ;
DR   B1XPQ6, PROB_SYNP2 ;  Q5N0T0, PROB_SYNP6 ;  Q7U842, PROB_SYNPX ;
DR   Q3AYS3, PROB_SYNS9 ;  Q3AIH2, PROB_SYNSC ;  P73071, PROB_SYNY3 ;
DR   C5BQB5, PROB_TERTT ;  Q8DH42, PROB_THEEB ;  Q47MV7, PROB_THEFY ;
DR   Q9WYD0, PROB_THEMA ;  B0K9C4, PROB_THEP3 ;  B0K0T1, PROB_THEPX ;
DR   Q60050, PROB_THET2 ;  Q5SH03, PROB_THET8 ;  Q8RAE6, PROB_THETN ;
DR   Q31IT3, PROB_THICR ;  Q3SJS7, PROB_THIDA ;  B8GQQ4, PROB_THISH ;
DR   P74936, PROB_TREPA ;  B2S2U8, PROB_TREPS ;  C5CXX2, PROB_VARPS ;
DR   A1WPR4, PROB_VEREI ;  Q9KPT8, PROB_VIBCH ;  Q5E6W1, PROB_VIBF1 ;
DR   A7MWT6, PROB_VIBHB ;  Q87RV0, PROB_VIBPA ;  Q8DF93, PROB_VIBVU ;
DR   Q7MN59, PROB_VIBVY ;  Q7MA27, PROB_WOLSU ;  Q8PK34, PROB_XANAC ;
DR   Q3BSJ0, PROB_XANC5 ;  Q4UVI1, PROB_XANC8 ;  Q8P8K2, PROB_XANCP ;
DR   Q2P2G0, PROB_XANOM ;  Q5GZF1, PROB_XANOR ;  B2I7L1, PROB_XYLF2 ;
DR   Q9PEM4, PROB_XYLFA ;  B0U207, PROB_XYLFM ;  Q87EL0, PROB_XYLFT ;
DR   P32264, PROB_YEAST ;  A1JNX7, PROB_YERE8 ;  A7FLI2, PROB_YERP3 ;
DR   Q1C4E6, PROB_YERPA ;  B2K6Q3, PROB_YERPB ;  Q8ZC08, PROB_YERPE ;
DR   A9R2X1, PROB_YERPG ;  Q1CLC7, PROB_YERPN ;  A4TPK1, PROB_YERPP ;
DR   Q66DY9, PROB_YERPS ;  B1JIH3, PROB_YERPY ;  Q5NR24, PROB_ZYMMO ;
DR   O07509, PROJ_BACSU ;
//
ID   2.7.2.12
DE   Acetate kinase (diphosphate).
AN   Acetate kinase (pyrophosphate).
CA   Diphosphate + acetate = phosphate + acetyl phosphate.
//
ID   2.7.2.13
DE   Glutamate 1-kinase.
CA   ATP + L-glutamate = ADP + alpha-L-glutamyl phosphate.
//
ID   2.7.2.14
DE   Branched-chain-fatty-acid kinase.
AN   Isobutyrate kinase.
CA   ATP + 2-methylpropanoate = ADP + 2-methylpropanoyl phosphate.
CC   -!- 3-methylbutanoate, 2-methylbutanoate, pentanoate, butanoate,
CC       and propanoate can also act as acceptors (cf. EC 2.7.2.7).
//
ID   2.7.2.15
DE   Propionate kinase.
AN   Propionate/acetate kinase.
CA   (1) ATP + propanoate = ADP + propanoyl phosphate.
CA   (2) ATP + acetate = ADP + acetyl phosphate.
CF   Magnesium.
CC   -!- Both propanoate and acetate can act as a substrate.
CC   -!- Involved in the anaerobic degradation of L-threonine in bacteria.
CC   -!- Both this enzyme and EC 2.7.2.1 play important roles in the
CC       production of propanoate.
PR   PROSITE; PDOC00826;
DR   A8AEL8, PDUW_CITK8 ;  D2TPS5, PDUW_CITRI ;  B7LTX5, PDUW_ESCF3 ;
DR   B5XUR6, PDUW_KLEP3 ;  A6TDE9, PDUW_KLEP7 ;  C0Q1L8, PDUW_SALPC ;
DR   P74879, PDUW_SALTY ;  C4LFE6, PDUW_TOLAT ;  A1JTT9, PDUW_YERE8 ;
DR   A8AQ07, TDCD_CITK8 ;  Q8XAF1, TDCD_ECO57 ;  P59244, TDCD_ECOL6 ;
DR   P11868, TDCD_ECOLI ;  D0ZE10, TDCD_EDWTE ;  A4WEU0, TDCD_ENT38 ;
DR   B5XVZ8, TDCD_KLEP3 ;  B5F6P9, TDCD_SALA4 ;  C9XHG0, TDCD_SALTD ;
DR   Q8Z3K5, TDCD_SALTI ;  O06961, TDCD_SALTY ;  A1JIM9, TDCD_YERE8 ;
//
ID   2.7.3.1
DE   Guanidinoacetate kinase.
AN   Glycocyamine kinase.
CA   ATP + guanidinoacetate = ADP + phosphoguanidinoacetate.
DR   P51546, KGCY_HEDDI ;
//
ID   2.7.3.2
DE   Creatine kinase.
CA   ATP + creatine = ADP + phosphocreatine.
CC   -!- N-ethylglycocyamine can also act as acceptor.
PR   PROSITE; PDOC00103;
DR   Q5EA61, KCRB_BOVIN ;  P05124, KCRB_CANFA ;  P05122, KCRB_CHICK ;
DR   P12277, KCRB_HUMAN ;  Q04447, KCRB_MOUSE ;  Q29594, KCRB_PIG   ;
DR   P00567, KCRB_RABIT ;  P07335, KCRB_RAT   ;  P26460, KCRB_SQUAC ;
DR   P18294, KCRF_STRPU ;  Q9XSC6, KCRM_BOVIN ;  P05123, KCRM_CANFA ;
DR   P00565, KCRM_CHICK ;  P06732, KCRM_HUMAN ;  P07310, KCRM_MOUSE ;
DR   Q5XLD3, KCRM_PIG   ;  P00563, KCRM_RABIT ;  P00564, KCRM_RAT   ;
DR   P04414, KCRM_TORCA ;  P00566, KCRM_TORMA ;  Q3ZBP1, KCRS_BOVIN ;
DR   P11009, KCRS_CHICK ;  P17540, KCRS_HUMAN ;  Q6P8J7, KCRS_MOUSE ;
DR   Q5R7B5, KCRS_PONAB ;  O77814, KCRS_RABIT ;  P09605, KCRS_RAT   ;
DR   P24722, KCRT_ONCMY ;  Q9TTK8, KCRU_BOVIN ;  P70079, KCRU_CHICK ;
DR   P12532, KCRU_HUMAN ;  P30275, KCRU_MOUSE ;  Q29577, KCRU_PIG   ;
DR   P25809, KCRU_RAT   ;
//
ID   2.7.3.3
DE   Arginine kinase.
AN   Arginine phosphokinase.
CA   ATP + L-arginine = ADP + N(omega)-phospho-L-arginine.
PR   PROSITE; PDOC00103;
DR   Q10454, KARG1_CAEEL;  Q27535, KARG2_CAEEL;  O15992, KARG_ANTJA ;
DR   O61367, KARG_APIME ;  Q95V58, KARG_ARTSF ;  Q9NH49, KARG_CALSI ;
DR   Q9U9J4, KARG_CARMA ;  P86699, KARG_CHIOP ;  P48610, KARG_DROME ;
DR   Q9NH48, KARG_ERISI ;  P51544, KARG_HALMK ;  P14208, KARG_HOMGA ;
DR   P51541, KARG_LIMPO ;  O15990, KARG_LIOJA ;  Q9GYX1, KARG_PACMR ;
DR   P51545, KARG_PENJP ;  C7E3T4, KARG_PENMO ;  Q95PM9, KARG_PLOIN ;
DR   P91798, KARG_SCHAM ;  Q9XY07, KARG_STIJA ;  O96507, KARG_TRYCR ;
DR   O15989, KARG_TURCO ;
//
ID   2.7.3.4
DE   Taurocyamine kinase.
CA   ATP + taurocyamine = ADP + N-phosphotaurocyamine.
PR   PROSITE; PDOC00103;
DR   P11917, KTRC_AREMA ;  P16641, KTRC_SCHMA ;
//
ID   2.7.3.5
DE   Lombricine kinase.
CA   ATP + lombricine = ADP + N-phospholombricine.
CC   -!- Also acts on methylated lombricines such as thalassemine; the
CC       specificity varies with the source species.
PR   PROSITE; PDOC00103;
DR   O15991, KLOM_EISFO ;  P11918, KLOM_LUMTE ;
//
ID   2.7.3.6
DE   Hypotaurocyamine kinase.
CA   ATP + hypotaurocyamine = ADP + N(omega)-phosphohypotaurocyamine.
CC   -!- Also acts, more slowly, on taurocyamine.
//
ID   2.7.3.7
DE   Opheline kinase.
CA   ATP + guanidinoethyl methyl phosphate = ADP +
CA   N'-phosphoguanidinoethyl methylphosphate.
CC   -!- Has a little activity on taurocyamine, lombricine and
CC       phosphotaurocyamine.
//
ID   2.7.3.8
DE   Ammonia kinase.
CA   ATP + NH(3) = ADP + phosphoramide.
CC   -!- Has a wide specificity.
CC   -!- In the reverse direction, N-phosphoglycine and N-phosphohistidine can
CC       also act as phosphate donors, and ADP, dADP, GDP, CDP, dTDP, dCDP,
CC       IDP and UDP can act as phosphate acceptors (in decreasing order of
CC       activity).
//
ID   2.7.3.9
DE   Phosphoenolpyruvate--protein phosphotransferase.
AN   Enzyme I of the phosphotransferase system.
AN   Phosphoenolpyruvate sugar phosphotransferase enzyme I.
AN   Phosphoenolpyruvate--protein phosphatase.
AN   Phosphopyruvate--protein factor phosphotransferase.
AN   Phosphopyruvate--protein phosphotransferase.
AN   Sugar--PEP phosphotransferase enzyme I.
CA   Phosphoenolpyruvate + protein L-histidine = pyruvate + protein N(pi)-
CA   phospho-L-histidine.
CC   -!- Acts only on histidine residues in specific phosphocarrier proteins
CC       of low molecular mass (9.5 kDa) involved in bacterial sugar
CC       transport.
CC   -!- A similar reaction where the protein is the enzyme EC 2.7.9.2 is part
CC       of the mechanism of that enzyme.
PR   PROSITE; PDOC00527;
DR   P37177, PT1P_ECOLI ;  P37178, PT1P_SALTY ;  Q9K8D3, PT1_BACHD  ;
DR   O69251, PT1_BACME  ;  O83018, PT1_BACSI  ;  P08838, PT1_BACSU  ;
DR   O51508, PT1_BORBU  ;  Q9WXI6, PT1_BUCAI  ;  Q8KA50, PT1_BUCAP  ;
DR   Q89B04, PT1_BUCBP  ;  Q9PK57, PT1_CHLMU  ;  Q9Z9E3, PT1_CHLPN  ;
DR   O84340, PT1_CHLTR  ;  P23536, PT1_CUPNH  ;  P08839, PT1_ECOLI  ;
DR   P23530, PT1_ENTFA  ;  P42014, PT1_GEOSE  ;  P43922, PT1_HAEIN  ;
DR   Q9CJ82, PT1_LACLA  ;  Q9ZAD8, PT1_LACLC  ;  O07126, PT1_LACSK  ;
DR   Q92D19, PT1_LISIN  ;  O31149, PT1_LISMO  ;  Q84F83, PT1_LYSSH  ;
DR   P45617, PT1_MYCCT  ;  P47668, PT1_MYCGE  ;  P75168, PT1_MYCPN  ;
DR   P0A250, PT1_SALTI  ;  P0A249, PT1_SALTY  ;  Q5HH01, PT1_STAAC  ;
DR   Q931U2, PT1_STAAM  ;  Q99V14, PT1_STAAN  ;  Q6GI01, PT1_STAAR  ;
DR   Q6GAD0, PT1_STAAS  ;  P51183, PT1_STAAU  ;  Q8NX83, PT1_STAAW  ;
DR   P23533, PT1_STACT  ;  Q5HQ85, PT1_STAEQ  ;  Q8CT19, PT1_STAES  ;
DR   Q9KZP1, PT1_STRCO  ;  Q9WXK9, PT1_STREI  ;  P45595, PT1_STRMU  ;
DR   P30299, PT1_STRSL  ;  Q8XBQ8, PTFAX_ECO57;  Q8FFD8, PTFAX_ECOL6;
DR   P23388, PTFAX_RHOCA;  Q83QP3, PTFAX_SHIFL;  P45597, PTFAX_XANCP;
DR   P77439, PTFX1_ECOLI;  P32670, PTFX2_ECOLI;
//
ID   2.7.3.10
DE   Agmatine kinase.
AN   Phosphagen phosphokinase.
CA   ATP + agmatine = ADP + N(4)-phosphoagmatine.
CC   -!- L-arginine can act as acceptor, more slowly.
//
ID   2.7.3.11
DE   Transferred entry: 2.7.13.1.
//
ID   2.7.3.12
DE   Transferred entry: 2.7.13.2.
//
ID   2.7.4.1
DE   Polyphosphate kinase.
AN   ATP-polyphosphate phosphotransferase.
AN   Polyphosphoric acid kinase.
CA   ATP + (phosphate)(n) = ADP + (phosphate)(n+1).
DR   P58991, PPK1_CHLTE ;  O68984, PPK2_CHLTE ;  B7GXW8, PPK_ACIB3  ;
DR   Q9X4M8, PPK_ACIBA  ;  A3M3C8, PPK_ACIBT  ;  B0V9M3, PPK_ACIBY  ;
DR   A5G1J3, PPK_ACICJ  ;  Q93AK9, PPK_APHBL  ;  A8IMV5, PPK_AZOC5  ;
DR   Q81MN9, PPK_BACAN  ;  Q819I5, PPK_BACCR  ;  Q9KD27, PPK_BACHD  ;
DR   Q6G327, PPK_BARHE  ;  A5EID1, PPK_BRASB  ;  A4YTA9, PPK_BRASO  ;
DR   B1YMX3, PPK_BURA4  ;  B1JZG0, PPK_BURCC  ;  A0K6D2, PPK_BURCH  ;
DR   Q0BGI1, PPK_BURCM  ;  A9ACK7, PPK_BURM1  ;  B2SZQ7, PPK_BURPP  ;
DR   Q39HM0, PPK_BURS3  ;  A4JDB7, PPK_BURVG  ;  O32350, PPK_CAMCO  ;
DR   A7I3Z5, PPK_CAMHC  ;  A8FN39, PPK_CAMJ8  ;  A7H220, PPK_CAMJD  ;
DR   Q9PMU0, PPK_CAMJE  ;  A1W0X7, PPK_CAMJJ  ;  Q5HT53, PPK_CAMJR  ;
DR   B9KCQ6, PPK_CAMLR  ;  Q54BM7, PPK_DICDI  ;  P0A7B2, PPK_ECO57  ;
DR   Q8FF70, PPK_ECOL6  ;  P0A7B1, PPK_ECOLI  ;  Q2NC49, PPK_ERYLH  ;
DR   B1YL94, PPK_EXIS2  ;  C4L3Y8, PPK_EXISA  ;  Q9ZM10, PPK_HELPJ  ;
DR   O25654, PPK_HELPY  ;  Q07411, PPK_KLEPN  ;  Q88YD2, PPK_LACPL  ;
DR   A0QJB3, PPK_MYCA1  ;  P65769, PPK_MYCBO  ;  A1KMX8, PPK_MYCBP  ;
DR   C1AG99, PPK_MYCBT  ;  A4TE29, PPK_MYCGI  ;  B8ZS08, PPK_MYCLB  ;
DR   O33127, PPK_MYCLE  ;  B2HII5, PPK_MYCMM  ;  Q73VJ1, PPK_MYCPA  ;
DR   A5U6Z5, PPK_MYCTA  ;  P65768, PPK_MYCTU  ;  A0PQ00, PPK_MYCUA  ;
DR   Q5FAJ0, PPK_NEIG1  ;  A9M159, PPK_NEIM0  ;  Q9JW42, PPK_NEIMA  ;
DR   Q9JXS9, PPK_NEIMB  ;  Q3SS86, PPK_NITWN  ;  B4S7P3, PPK_PROA2  ;
DR   Q7V3U5, PPK_PROMM  ;  Q9S646, PPK_PSEAE  ;  Q88CG4, PPK_PSEPK  ;
DR   Q87UP6, PPK_PSESM  ;  Q7ULJ4, PPK_RHOBA  ;  Q2IX63, PPK_RHOP2  ;
DR   B3Q9Q6, PPK_RHOPT  ;  Q8Z4R0, PPK_SALTI  ;  O86090, PPK_SALTY  ;
DR   Q5HLE0, PPK_STAEQ  ;  Q8CR71, PPK_STAES  ;  Q4L8X9, PPK_STAHJ  ;
DR   Q4A040, PPK_STAS1  ;  Q9KZV6, PPK_STRCO  ;  Q9EUS8, PPK_STRGR  ;
DR   Q7U3D7, PPK_SYNPX  ;  Q55898, PPK_SYNY3  ;  Q8DMA8, PPK_THEEB  ;
DR   Q9KU07, PPK_VIBCH  ;  Q87S51, PPK_VIBPA  ;  Q8DEW2, PPK_VIBVU  ;
DR   Q7MNJ0, PPK_VIBVY  ;  A7IK14, PPK_XANP2  ;  Q9PAC7, PPK_XYLFA  ;
DR   Q87A63, PPK_XYLFT  ;  Q8ZCX2, PPK_YERPE  ;
//
ID   2.7.4.2
DE   Phosphomevalonate kinase.
CA   ATP + (R)-5-phosphomevalonate = ADP + (R)-5-diphosphomevalonate.
PR   PROSITE; PDOC00545;
DR   Q9UT88, ERG8_SCHPO ;  P24521, ERG8_YEAST ;  Q2KIU2, PMVK_BOVIN ;
DR   Q9VIT2, PMVK_DROME ;  Q15126, PMVK_HUMAN ;  Q9D1G2, PMVK_MOUSE ;
DR   Q29081, PMVK_PIG   ;
//
ID   2.7.4.3
DE   Adenylate kinase.
AN   Adenylic kinase.
AN   Adenylokinase.
AN   Myokinase.
CA   ATP + AMP = 2 ADP.
CC   -!- Inorganic triphosphate can also act as donor.
PR   PROSITE; PDOC00104;
DR   Q59W41, KAD11_CANAL;  Q5A4Q1, KAD12_CANAL;  A6RHI1, KAD1_AJECN ;
DR   O82514, KAD1_ARATH ;  Q74ZL1, KAD1_ASHGO ;  A1CQR5, KAD1_ASPCL ;
DR   B0XPW9, KAD1_ASPFC ;  Q4WJ21, KAD1_ASPFU ;  A2QPN9, KAD1_ASPNC ;
DR   Q2UBH0, KAD1_ASPOR ;  Q0C7Y1, KAD1_ASPTN ;  A6RPU0, KAD1_BOTFB ;
DR   P00570, KAD1_BOVIN ;  Q20140, KAD1_CAEEL ;  Q6FM32, KAD1_CANGA ;
DR   Q2GVK6, KAD1_CHAGB ;  P05081, KAD1_CHICK ;  Q1E4I8, KAD1_COCIM ;
DR   A8PAA1, KAD1_COPC7 ;  P0CO43, KAD1_CRYNB ;  P0CO42, KAD1_CRYNJ ;
DR   P12115, KAD1_CYPCA ;  Q6BLN9, KAD1_DEBHA ;  Q5B2V8, KAD1_EMENI ;
DR   P00568, KAD1_HUMAN ;  Q6CK57, KAD1_KLULA ;  B0D360, KAD1_LACBS ;
DR   A5E598, KAD1_LODEL ;  A4RD93, KAD1_MAGO7 ;  A8PR17, KAD1_MALGO ;
DR   P86195, KAD1_MESAU ;  Q9R0Y5, KAD1_MOUSE ;  A1D3M8, KAD1_NEOFI ;
DR   Q9HE76, KAD1_NEUCR ;  Q8YPJ8, KAD1_NOSS1 ;  Q08479, KAD1_ORYSJ ;
DR   B2CNY4, KAD1_PENMA ;  Q0V3D5, KAD1_PHANO ;  A5DC72, KAD1_PICGU ;
DR   A3LV51, KAD1_PICST ;  P00571, KAD1_PIG   ;  B2B0E2, KAD1_PODAN ;
DR   B2W0K4, KAD1_PYRTR ;  P00569, KAD1_RABIT ;  P39069, KAD1_RAT   ;
DR   P33075, KAD1_SCHPO ;  A7E8H8, KAD1_SCLS1 ;  P73302, KAD1_SYNY3 ;
DR   Q4PCS5, KAD1_USTMA ;  A7THY5, KAD1_VANPO ;  Q6CG57, KAD1_YARLI ;
DR   B3LG61, KAD1_YEAS1 ;  A6ZYI0, KAD1_YEAS7 ;  P07170, KAD1_YEAST ;
DR   Q1HQK0, KAD2_AEDAE ;  Q7QJX9, KAD2_ANOGA ;  Q9FK35, KAD2_ARATH ;
DR   P08166, KAD2_BOVIN ;  A8XZJ0, KAD2_CAEBR ;  P34346, KAD2_CAEEL ;
DR   B0X5E3, KAD2_CULQU ;  Q1L8L9, KAD2_DANRE ;  Q54QJ9, KAD2_DICDI ;
DR   B3MCQ5, KAD2_DROAN ;  B3NQ53, KAD2_DROER ;  B4J672, KAD2_DROGR ;
DR   Q9U915, KAD2_DROME ;  B4KLY1, KAD2_DROMO ;  Q290A8, KAD2_DROPS ;
DR   B4I2A8, KAD2_DROSE ;  B4QBH8, KAD2_DROSI ;  B4LP08, KAD2_DROVI ;
DR   B4MQT3, KAD2_DROWI ;  B4PAR6, KAD2_DROYA ;  P54819, KAD2_HUMAN ;
DR   Q9WTP6, KAD2_MOUSE ;  Q8Z0M3, KAD2_NOSS1 ;  Q08480, KAD2_ORYSJ ;
DR   Q5REI7, KAD2_PONAB ;  P29410, KAD2_RAT   ;  B5XCA1, KAD2_SALSA ;
DR   P72641, KAD2_SYNY3 ;  Q8AVD3, KAD2_XENLA ;  Q28F55, KAD2_XENTR ;
DR   P26364, KAD2_YEAST ;  Q0VCP1, KAD4_BOVIN ;  P27144, KAD4_HUMAN ;
DR   Q9WUR9, KAD4_MOUSE ;  Q5R421, KAD4_PONAB ;  Q9WUS0, KAD4_RAT   ;
DR   A4IFD0, KAD5_BOVIN ;  Q9Y6K8, KAD5_HUMAN ;  Q920P5, KAD5_MOUSE ;
DR   O28278, KAD6_ARCFU ;  A5PJA1, KAD6_BOVIN ;  Q09527, KAD6_CAEEL ;
DR   Q8TG40, KAD6_CANAL ;  Q54Y03, KAD6_DICDI ;  B0R4Q3, KAD6_HALS3 ;
DR   Q9HQS1, KAD6_HALSA ;  Q9Y3D8, KAD6_HUMAN ;  Q8TJQ0, KAD6_METAC ;
DR   Q46FV0, KAD6_METBF ;  Q58450, KAD6_METJA ;  Q8TWH4, KAD6_METKA ;
DR   A6VHC3, KAD6_METM7 ;  Q8PZ69, KAD6_METMA ;  A4YIQ9, KAD6_METS5 ;
DR   O27656, KAD6_METTH ;  Q8VCP8, KAD6_MOUSE ;  Q3IRT0, KAD6_NATPD ;
DR   Q9UZK4, KAD6_PYRAB ;  Q8ZU30, KAD6_PYRAE ;  Q8U1S1, KAD6_PYRFU ;
DR   O58998, KAD6_PYRHO ;  Q5JG26, KAD6_PYRKO ;  Q9TTU2, KAD6_RABIT ;
DR   Q5EB68, KAD6_RAT   ;  Q9UU88, KAD6_SCHPO ;  C3N6L0, KAD6_SULIA ;
DR   C4KI81, KAD6_SULIK ;  C3MQV5, KAD6_SULIL ;  C3MWU3, KAD6_SULIM ;
DR   C3NGL3, KAD6_SULIN ;  C3N6Z8, KAD6_SULIY ;  Q97ZW3, KAD6_SULSO ;
DR   Q976L5, KAD6_SULTO ;  Q9HKM7, KAD6_THEAC ;  C5A628, KAD6_THEGJ ;
DR   B6YUL3, KAD6_THEON ;  Q97B38, KAD6_THEVO ;  Q12055, KAD6_YEAST ;
DR   Q96M32, KAD7_HUMAN ;  Q95JP6, KAD7_MACFA ;  Q9D2H2, KAD7_MOUSE ;
DR   Q502L7, KAD8_DANRE ;  Q96MA6, KAD8_HUMAN ;  Q4R3W4, KAD8_MACFA ;
DR   Q32M07, KAD8_MOUSE ;  Q68FP8, KAD8_RAT   ;  Q5M7G4, KAD8_XENLA ;
DR   Q6P618, KAD8_XENTR ;  Q9YDD2, KADA_AERPE ;  A6UW35, KADA_META3 ;
DR   P43408, KADA_METIG ;  P43409, KADA_METJA ;  Q8TZB0, KADA_METKA ;
DR   A4FXE7, KADA_METM5 ;  A9AAR7, KADA_METM6 ;  A6VFX9, KADA_METM7 ;
DR   A3CT21, KADA_METMJ ;  Q6LYG0, KADA_METMP ;  O26135, KADA_METTH ;
DR   P43410, KADA_METTL ;  P43411, KADA_METVO ;  A6UP41, KADA_METVS ;
DR   Q9V1V9, KADA_PYRAB ;  Q8ZWP7, KADA_PYRAE ;  Q8U020, KADA_PYRFU ;
DR   O59443, KADA_PYRHO ;  Q5JJH2, KADA_PYRKO ;  P35028, KADA_SULAC ;
DR   C3N5V1, KADA_SULIA ;  C4KHI0, KADA_SULIK ;  C3MQ83, KADA_SULIL ;
DR   C3MVK2, KADA_SULIM ;  C3NH85, KADA_SULIN ;  C3NEG7, KADA_SULIY ;
DR   Q9UX83, KADA_SULSO ;  Q975K4, KADA_SULTO ;  Q9HIT1, KADA_THEAC ;
DR   C5A261, KADA_THEGJ ;  B6YSN8, KADA_THEON ;  C6A184, KADA_THESM ;
DR   Q97BV2, KADA_THEVO ;  Q54CT8, KADB_DICDI ;  Q9ZUU1, KADC1_ARATH;
DR   Q9FIJ7, KADC2_ARATH;  P43188, KADC_MAIZE ;  Q8HSW1, KADC_SOLTU ;
DR   P49983, KADH_TRIVA ;  Q8SVC2, KADL_ENCCU ;  Q09629, KADY_CAEEL ;
DR   A9NEF4, KAD_ACHLI  ;  A1TQ96, KAD_ACIAC  ;  Q6FD71, KAD_ACIAD  ;
DR   B7GXT4, KAD_ACIB3  ;  B7I8U4, KAD_ACIB5  ;  B2HVT0, KAD_ACIBC  ;
DR   B0VSA9, KAD_ACIBS  ;  A3M3G1, KAD_ACIBT  ;  B0V9Q9, KAD_ACIBY  ;
DR   A0LRP1, KAD_ACIC1  ;  A5FZU4, KAD_ACICJ  ;  B9MI80, KAD_ACIET  ;
DR   A1W895, KAD_ACISJ  ;  A3N1U8, KAD_ACTP2  ;  B3H271, KAD_ACTP7  ;
DR   B0BQN2, KAD_ACTPJ  ;  A6VQC3, KAD_ACTSZ  ;  A0KL52, KAD_AERHH  ;
DR   A4SLY1, KAD_AERS4  ;  B9JDU9, KAD_AGRRK  ;  Q8UE38, KAD_AGRT5  ;
DR   B9JVQ8, KAD_AGRVS  ;  Q0VRB0, KAD_ALCBS  ;  Q0A982, KAD_ALHEH  ;
DR   B6EHK0, KAD_ALISL  ;  A8MLG1, KAD_ALKOO  ;  B4RU55, KAD_ALTMD  ;
DR   B8J881, KAD_ANAD2  ;  Q2IJ70, KAD_ANADE  ;  A7HBN9, KAD_ANADF  ;
DR   B4UBC0, KAD_ANASK  ;  B9MKG1, KAD_ANATD  ;  O66490, KAD_AQUAE  ;
DR   O29581, KAD_ARCFU  ;  Q5P106, KAD_AROAE  ;  B8HCY6, KAD_ARTCA  ;
DR   Q2NIX5, KAD_AYWBP  ;  A8IAP0, KAD_AZOC5  ;  B6YRA7, KAD_AZOPC  ;
DR   A1K5I5, KAD_AZOSB  ;  C1DSX5, KAD_AZOVD  ;  A7Z0Q9, KAD_BACA2  ;
DR   C3P9S6, KAD_BACAA  ;  C3LJA3, KAD_BACAC  ;  A0R8K1, KAD_BACAH  ;
DR   Q81VQ9, KAD_BACAN  ;  B7JKE1, KAD_BACC0  ;  Q73F75, KAD_BACC1  ;
DR   B7IT40, KAD_BACC2  ;  C1ET60, KAD_BACC3  ;  B7HJ69, KAD_BACC4  ;
DR   B7HQW5, KAD_BACC7  ;  A7GK41, KAD_BACCN  ;  B9IZL5, KAD_BACCQ  ;
DR   Q81J22, KAD_BACCR  ;  Q63H69, KAD_BACCZ  ;  Q5LGH0, KAD_BACFN  ;
DR   Q64XA6, KAD_BACFR  ;  P84139, KAD_BACGO  ;  P38372, KAD_BACHD  ;
DR   Q6HPN7, KAD_BACHK  ;  P35140, KAD_BACLD  ;  A8F9A6, KAD_BACP2  ;
DR   Q5WLP1, KAD_BACSK  ;  P16304, KAD_BACSU  ;  Q89ZJ0, KAD_BACTN  ;
DR   A6L0Z9, KAD_BACV8  ;  A9VP98, KAD_BACWK  ;  A1USR5, KAD_BARBK  ;
DR   Q6G2Y6, KAD_BARHE  ;  Q6FZE3, KAD_BARQU  ;  A9IVZ9, KAD_BART1  ;
DR   Q1LTX5, KAD_BAUCH  ;  P61115, KAD_BDEBA  ;  B2IK83, KAD_BEII9  ;
DR   Q8G3Z8, KAD_BIFLO  ;  Q7VRB6, KAD_BLOFL  ;  Q493A3, KAD_BLOPB  ;
DR   Q2KZE4, KAD_BORA1  ;  Q7WKU8, KAD_BORBR  ;  O51378, KAD_BORBU  ;
DR   B5RLX5, KAD_BORDL  ;  Q661K1, KAD_BORGA  ;  Q7W7G0, KAD_BORPA  ;
DR   A9IQ39, KAD_BORPD  ;  P39068, KAD_BORPE  ;  B5RRM3, KAD_BORRA  ;
DR   A1QZK3, KAD_BORT9  ;  C0R000, KAD_BRAHW  ;  C0ZIK1, KAD_BREBN  ;
DR   B2S658, KAD_BRUA1  ;  Q2YRT7, KAD_BRUA2  ;  Q57CS9, KAD_BRUAB  ;
DR   A9M5M9, KAD_BRUC2  ;  C0RJI0, KAD_BRUMB  ;  Q8YHL9, KAD_BRUME  ;
DR   A5VQY5, KAD_BRUO2  ;  B0CH11, KAD_BRUSI  ;  Q8G092, KAD_BRUSU  ;
DR   B8D9R1, KAD_BUCA5  ;  P57556, KAD_BUCAI  ;  Q8K980, KAD_BUCAP  ;
DR   B8D813, KAD_BUCAT  ;  P59429, KAD_BUCBP  ;  Q057D8, KAD_BUCCC  ;
DR   B1YVE0, KAD_BURA4  ;  Q1BU66, KAD_BURCA  ;  B1JXF8, KAD_BURCC  ;
DR   A0K9X1, KAD_BURCH  ;  B4E9G1, KAD_BURCJ  ;  Q0BCH1, KAD_BURCM  ;
DR   A9AGK1, KAD_BURM1  ;  A3MN48, KAD_BURM7  ;  A2S516, KAD_BURM9  ;
DR   Q62HI0, KAD_BURMA  ;  A1V117, KAD_BURMS  ;  A3NS87, KAD_BURP0  ;
DR   Q3JVB1, KAD_BURP1  ;  A3N6K4, KAD_BURP6  ;  B2JDV1, KAD_BURP8  ;
DR   B2T6M4, KAD_BURPP  ;  Q63WL6, KAD_BURPS  ;  Q39DJ3, KAD_BURS3  ;
DR   Q2T0K4, KAD_BURTA  ;  A4JH80, KAD_BURVG  ;  Q13UR8, KAD_BURXL  ;
DR   A4XLR0, KAD_CALS8  ;  A7ZEH4, KAD_CAMC1  ;  A7GXF6, KAD_CAMC5  ;
DR   A0RQ72, KAD_CAMFF  ;  A7I057, KAD_CAMHC  ;  A8FL60, KAD_CAMJ8  ;
DR   A7H4H3, KAD_CAMJD  ;  Q9PHM8, KAD_CAMJE  ;  A1VYZ9, KAD_CAMJJ  ;
DR   Q5HVD2, KAD_CAMJR  ;  B9KFZ2, KAD_CAMLR  ;  Q3ACG0, KAD_CARHZ  ;
DR   B8H4F5, KAD_CAUCN  ;  Q9A8T2, KAD_CAUCR  ;  B0T2E3, KAD_CAUSK  ;
DR   B3PIE4, KAD_CELJU  ;  Q5L5W0, KAD_CHLAB  ;  Q3ASD2, KAD_CHLCH  ;
DR   Q822Z1, KAD_CHLCV  ;  Q254P2, KAD_CHLFF  ;  B3ED51, KAD_CHLL2  ;
DR   Q9PKR0, KAD_CHLMU  ;  B3QNN0, KAD_CHLP8  ;  B3EJF7, KAD_CHLPB  ;
DR   A1BGN6, KAD_CHLPD  ;  Q9Z8U0, KAD_CHLPN  ;  B0B9N6, KAD_CHLT2  ;
DR   B3QS41, KAD_CHLT3  ;  Q3KMP1, KAD_CHLTA  ;  B0BBB5, KAD_CHLTB  ;
DR   Q8KD69, KAD_CHLTE  ;  O84130, KAD_CHLTR  ;  Q1QZ94, KAD_CHRSD  ;
DR   Q7NSS7, KAD_CHRVO  ;  A8AJW9, KAD_CITK8  ;  A5CU93, KAD_CLAM3  ;
DR   B0RB59, KAD_CLAMS  ;  Q97EJ9, KAD_CLOAB  ;  A7FZ52, KAD_CLOB1  ;
DR   C3KVN0, KAD_CLOB6  ;  A6LPT2, KAD_CLOB8  ;  B2UYD1, KAD_CLOBA  ;
DR   B2TIJ6, KAD_CLOBB  ;  A5I7I5, KAD_CLOBH  ;  C1FMT0, KAD_CLOBJ  ;
DR   B1IGD3, KAD_CLOBK  ;  A7GJ53, KAD_CLOBL  ;  B1KSK4, KAD_CLOBM  ;
DR   B8I800, KAD_CLOCE  ;  Q18CH9, KAD_CLOD6  ;  B9DYD0, KAD_CLOK1  ;
DR   A5N4R8, KAD_CLOK5  ;  A0PXW7, KAD_CLONN  ;  Q0TMR7, KAD_CLOP1  ;
DR   Q8XHU4, KAD_CLOPE  ;  A9KJH3, KAD_CLOPH  ;  Q0SQG5, KAD_CLOPS  ;
DR   Q890Q5, KAD_CLOTE  ;  A3DJJ3, KAD_CLOTH  ;  Q47XA8, KAD_COLP3  ;
DR   C3PL31, KAD_CORA7  ;  Q6NJ71, KAD_CORDI  ;  Q8FS39, KAD_COREF  ;
DR   A4QBP4, KAD_CORGB  ;  P49973, KAD_CORGL  ;  Q4JTB5, KAD_CORJK  ;
DR   C4LL05, KAD_CORK4  ;  B1VEX6, KAD_CORU7  ;  B6J8H9, KAD_COXB1  ;
DR   B6J1M3, KAD_COXB2  ;  A9KED8, KAD_COXBN  ;  A9NBU5, KAD_COXBR  ;
DR   Q83E75, KAD_COXBU  ;  Q0KE20, KAD_CUPNH  ;  Q475G1, KAD_CUPPJ  ;
DR   B3R0X7, KAD_CUPTR  ;  B8HMS3, KAD_CYAP4  ;  Q47B46, KAD_DECAR  ;
DR   Q3Z960, KAD_DEHE1  ;  A5FRW5, KAD_DEHSB  ;  Q3ZZQ3, KAD_DEHSC  ;
DR   C1CXE5, KAD_DEIDV  ;  Q1IX93, KAD_DEIGD  ;  Q9RSK7, KAD_DEIRA  ;
DR   A9BWI1, KAD_DELAS  ;  B8FMP4, KAD_DESAA  ;  C6BV58, KAD_DESAD  ;
DR   C0QB12, KAD_DESAH  ;  B1I3R5, KAD_DESAP  ;  B8J2T3, KAD_DESDA  ;
DR   B8G1Y7, KAD_DESHD  ;  Q250L1, KAD_DESHY  ;  C4XPE9, KAD_DESMR  ;
DR   A8ZTL5, KAD_DESOH  ;  Q6AMG3, KAD_DESPS  ;  A4J592, KAD_DESRM  ;
DR   Q72AR0, KAD_DESVH  ;  B8DPG3, KAD_DESVM  ;  A7ZIN4, KAD_ECO24  ;
DR   B7UKF4, KAD_ECO27  ;  B7MDZ6, KAD_ECO45  ;  B7L799, KAD_ECO55  ;
DR   P69442, KAD_ECO57  ;  B7NIF6, KAD_ECO7I  ;  B7MQI9, KAD_ECO81  ;
DR   B7M3W6, KAD_ECO8A  ;  C4ZUS8, KAD_ECOBW  ;  B1XFR1, KAD_ECODH  ;
DR   A7ZXD2, KAD_ECOHS  ;  Q0TKG7, KAD_ECOL5  ;  Q8FK84, KAD_ECOL6  ;
DR   B1IZC0, KAD_ECOLC  ;  P69441, KAD_ECOLI  ;  B7N927, KAD_ECOLU  ;
DR   B6I0C6, KAD_ECOSE  ;  B1LJN2, KAD_ECOSM  ;  C5BD16, KAD_EDWI9  ;
DR   B2KEK1, KAD_ELUMP  ;  A4W7F8, KAD_ENT38  ;  Q839E3, KAD_ENTFA  ;
DR   O96907, KAD_ENTHI  ;  Q6D7Z5, KAD_ERWCT  ;  B2VHX2, KAD_ERWT9  ;
DR   Q2N9D3, KAD_ERYLH  ;  B7LV13, KAD_ESCF3  ;  C4Z2V1, KAD_EUBE2  ;
DR   C4ZBT9, KAD_EUBR3  ;  B1YGX1, KAD_EXIS2  ;  C4KZM5, KAD_EXISA  ;
DR   A7HM31, KAD_FERNB  ;  B0RZT0, KAD_FINM2  ;  A5FMV7, KAD_FLAJ1  ;
DR   A6GZB9, KAD_FLAPJ  ;  B0TXR2, KAD_FRAP2  ;  Q14H66, KAD_FRAT1  ;
DR   A7NBG3, KAD_FRATF  ;  Q2A425, KAD_FRATH  ;  B2SGC2, KAD_FRATM  ;
DR   A0Q713, KAD_FRATN  ;  Q0BMG1, KAD_FRATO  ;  Q5NFR4, KAD_FRATT  ;
DR   A4IYJ6, KAD_FRATW  ;  Q8RE31, KAD_FUSNN  ;  C1A6S6, KAD_GEMAT  ;
DR   B5EFS1, KAD_GEOBB  ;  Q5L3R8, KAD_GEOKA  ;  B3E851, KAD_GEOLS  ;
DR   P27142, KAD_GEOSE  ;  B9M6F7, KAD_GEOSF  ;  Q749A8, KAD_GEOSL  ;
DR   C6E4N6, KAD_GEOSM  ;  C5D3T8, KAD_GEOSW  ;  A4IJK9, KAD_GEOTN  ;
DR   A5GAW3, KAD_GEOUR  ;  P49982, KAD_GIAIN  ;  Q7NKT5, KAD_GLOVI  ;
DR   A9H3J9, KAD_GLUDA  ;  Q7VMY0, KAD_HAEDU  ;  Q4QNJ1, KAD_HAEI8  ;
DR   A5UAD6, KAD_HAEIE  ;  A5UGF8, KAD_HAEIG  ;  P24323, KAD_HAEIN  ;
DR   Q0I2Y5, KAD_HAES1  ;  B0UT69, KAD_HAES2  ;  Q2SL21, KAD_HAHCH  ;
DR   A1WXY6, KAD_HALHL  ;  Q5UXG8, KAD_HALMA  ;  B0R683, KAD_HALS3  ;
DR   Q9HPA7, KAD_HALSA  ;  C4K7W8, KAD_HAMD5  ;  Q7VFA6, KAD_HELHP  ;
DR   B0TC77, KAD_HELMI  ;  B5Z6Y9, KAD_HELPG  ;  Q1CTQ6, KAD_HELPH  ;
DR   Q9ZLL8, KAD_HELPJ  ;  B2UTK9, KAD_HELPS  ;  P56104, KAD_HELPY  ;
DR   A4G7X8, KAD_HERAR  ;  B4U765, KAD_HYDS0  ;  Q0BYD5, KAD_HYPNA  ;
DR   Q5QWR3, KAD_IDILO  ;  A6T169, KAD_JANMA  ;  Q28UT2, KAD_JANSC  ;
DR   B5Y0N3, KAD_KLEP3  ;  A6T5N7, KAD_KLEP7  ;  B2GJ13, KAD_KOCRD  ;
DR   C5CGI1, KAD_KOSOT  ;  Q5FM70, KAD_LACAC  ;  B3WAJ7, KAD_LACCB  ;
DR   Q1GBJ7, KAD_LACDA  ;  Q04BZ4, KAD_LACDB  ;  B2GDU8, KAD_LACF3  ;
DR   Q046A5, KAD_LACGA  ;  A8YXM6, KAD_LACH4  ;  Q74L69, KAD_LACJO  ;
DR   P58117, KAD_LACLA  ;  P27143, KAD_LACLC  ;  A2RNN2, KAD_LACLM  ;
DR   Q02W46, KAD_LACLS  ;  Q88XW5, KAD_LACPL  ;  B2G8V7, KAD_LACRJ  ;
DR   Q38UT2, KAD_LACSS  ;  C1D6J0, KAD_LARHH  ;  Q1MRK3, KAD_LAWIP  ;
DR   Q5X5F4, KAD_LEGPA  ;  A5IBQ3, KAD_LEGPC  ;  Q5WWT7, KAD_LEGPL  ;
DR   Q6AD15, KAD_LEIXX  ;  B0SA26, KAD_LEPBA  ;  Q04PV9, KAD_LEPBJ  ;
DR   B0SSF7, KAD_LEPBP  ;  B1Y6I7, KAD_LEPCP  ;  Q72NI2, KAD_LEPIC  ;
DR   Q9XD15, KAD_LEPIN  ;  B1MVZ4, KAD_LEUCK  ;  Q03ZM5, KAD_LEUMM  ;
DR   Q927M8, KAD_LISIN  ;  C1KZF9, KAD_LISMC  ;  Q71WG7, KAD_LISMF  ;
DR   B8DB29, KAD_LISMH  ;  Q8Y449, KAD_LISMO  ;  A0ALU7, KAD_LISW6  ;
DR   B1HMV9, KAD_LYSSC  ;  Q2W2L1, KAD_MAGSA  ;  A0L8G8, KAD_MAGSM  ;
DR   Q65UF7, KAD_MANSM  ;  A1U2U2, KAD_MARAV  ;  Q0ANS1, KAD_MARMM  ;
DR   A6VUQ6, KAD_MARMS  ;  Q6F1X3, KAD_MESFL  ;  Q11HS3, KAD_MESSB  ;
DR   Q8TRS3, KAD_METAC  ;  Q46GB9, KAD_METBF  ;  Q12ZS7, KAD_METBU  ;
DR   B7L0S9, KAD_METC4  ;  Q606F1, KAD_METCA  ;  A9W4R9, KAD_METEP  ;
DR   Q1GZB7, KAD_METFK  ;  Q8PV26, KAD_METMA  ;  B8IT32, KAD_METNO  ;
DR   B1Z772, KAD_METPB  ;  A2SIQ4, KAD_METPP  ;  B1LWQ5, KAD_METRJ  ;
DR   B8ELE2, KAD_METSB  ;  A0B9A2, KAD_METTP  ;  C5CC42, KAD_MICLC  ;
DR   P33107, KAD_MICLU  ;  Q2RFR8, KAD_MOOTA  ;  B1MGB3, KAD_MYCA9  ;
DR   P69439, KAD_MYCBO  ;  A1KGL4, KAD_MYCBP  ;  C1AL67, KAD_MYCBT  ;
DR   P10251, KAD_MYCCT  ;  O52352, KAD_MYCGA  ;  P47417, KAD_MYCGE  ;
DR   Q601J4, KAD_MYCH2  ;  Q4A8J1, KAD_MYCH7  ;  Q4AAG0, KAD_MYCHJ  ;
DR   B8ZS96, KAD_MYCLB  ;  O33007, KAD_MYCLE  ;  B2HCV5, KAD_MYCMM  ;
DR   Q6KI35, KAD_MYCMO  ;  Q6MSP5, KAD_MYCMS  ;  Q73S77, KAD_MYCPA  ;
DR   Q8EUD3, KAD_MYCPE  ;  Q50299, KAD_MYCPN  ;  Q98Q02, KAD_MYCPU  ;
DR   A0QSH8, KAD_MYCS2  ;  A3PVF5, KAD_MYCSJ  ;  A1UBR9, KAD_MYCSK  ;
DR   Q1BD73, KAD_MYCSS  ;  A5U0B9, KAD_MYCTA  ;  P69440, KAD_MYCTU  ;
DR   A0PM98, KAD_MYCUA  ;  A1T4T2, KAD_MYCVP  ;  Q3IMW0, KAD_NATPD  ;
DR   B2A4G2, KAD_NATTJ  ;  B9L9Y8, KAD_NAUPA  ;  Q59591, KAD_NEIAN  ;
DR   Q59594, KAD_NEICI  ;  Q59596, KAD_NEIFL  ;  Q5F9J3, KAD_NEIG1  ;
DR   B4RKA2, KAD_NEIG2  ;  P49979, KAD_NEIGO  ;  Q59615, KAD_NEILA  ;
DR   A9M3Q2, KAD_NEIM0  ;  P0A0U6, KAD_NEIMA  ;  P0A0U7, KAD_NEIMB  ;
DR   P0DH56, KAD_NEIME  ;  A1KT73, KAD_NEIMF  ;  E6MY99, KAD_NEIMH  ;
DR   P49981, KAD_NEIMU  ;  Q59628, KAD_NEIPH  ;  Q59627, KAD_NEIPO  ;
DR   Q2GEB9, KAD_NEOSM  ;  Q1QN09, KAD_NITHX  ;  Q3J7A3, KAD_NITOC  ;
DR   A6Q322, KAD_NITSB  ;  Q3SSU5, KAD_NITWN  ;  Q5Z1Q1, KAD_NOCFA  ;
DR   A1SNJ7, KAD_NOCSJ  ;  Q2G8V9, KAD_NOVAD  ;  Q8ETW3, KAD_OCEIH  ;
DR   A6X0D9, KAD_OCHA4  ;  Q04G65, KAD_OENOB  ;  Q6YR01, KAD_ONYPE  ;
DR   A5CCJ2, KAD_ORITB  ;  B3CT26, KAD_ORITI  ;  A6LD69, KAD_PARD8  ;
DR   P10772, KAD_PARDE  ;  A1B049, KAD_PARDP  ;  A7HWT2, KAD_PARL1  ;
DR   P57837, KAD_PASMU  ;  C6DB87, KAD_PECCP  ;  Q3A6M6, KAD_PELCD  ;
DR   Q3B4C0, KAD_PELLD  ;  B4SA64, KAD_PELPB  ;  A1ALW2, KAD_PELPD  ;
DR   Q4FLN8, KAD_PELUB  ;  A9BFZ7, KAD_PETMO  ;  B4R8N8, KAD_PHEZH  ;
DR   Q7N0P5, KAD_PHOLL  ;  Q6LTE1, KAD_PHOPR  ;  B1VAC7, KAD_PHYAS  ;
DR   A1VNK2, KAD_POLNA  ;  B1XTC5, KAD_POLNS  ;  Q129C6, KAD_POLSJ  ;
DR   A4SVI8, KAD_POLSQ  ;  B2RIY8, KAD_PORG3  ;  Q7MW54, KAD_PORGI  ;
DR   B4S810, KAD_PROA2  ;  Q6A6Q4, KAD_PROAC  ;  A3PF28, KAD_PROM0  ;
DR   A2C4Y0, KAD_PROM1  ;  A8G742, KAD_PROM2  ;  A2CC47, KAD_PROM3  ;
DR   A9BCM8, KAD_PROM4  ;  A2BYR7, KAD_PROM5  ;  Q7V9Y1, KAD_PROMA  ;
DR   B4F1Q2, KAD_PROMH  ;  Q7V526, KAD_PROMM  ;  Q7UZW3, KAD_PROMP  ;
DR   A2BTB8, KAD_PROMS  ;  Q46IS8, KAD_PROMT  ;  A4SEQ7, KAD_PROVI  ;
DR   O24464, KAD_PRUAR  ;  Q48F36, KAD_PSE14  ;  Q15RT7, KAD_PSEA6  ;
DR   A6V1A1, KAD_PSEA7  ;  B7V109, KAD_PSEA8  ;  Q02RF8, KAD_PSEAB  ;
DR   Q9HXV4, KAD_PSEAE  ;  Q1IDV1, KAD_PSEE4  ;  Q4KHK4, KAD_PSEF5  ;
DR   C3KEC6, KAD_PSEFS  ;  Q3IKQ1, KAD_PSEHT  ;  A4XXP5, KAD_PSEMY  ;
DR   A5W880, KAD_PSEP1  ;  Q3KHE3, KAD_PSEPF  ;  B0KS64, KAD_PSEPG  ;
DR   P0A136, KAD_PSEPK  ;  P0A137, KAD_PSEPU  ;  B1JD29, KAD_PSEPW  ;
DR   Q886R8, KAD_PSESM  ;  Q4ZWV2, KAD_PSEU2  ;  A1STI3, KAD_PSYIN  ;
DR   Q9UZN1, KAD_PYRAB  ;  Q8U207, KAD_PYRFU  ;  O58844, KAD_PYRHO  ;
DR   Q5JH68, KAD_PYRKO  ;  Q1LR08, KAD_RALME  ;  B2UB85, KAD_RALPJ  ;
DR   Q8XWE1, KAD_RALSO  ;  A9WST7, KAD_RENSM  ;  B3PWU2, KAD_RHIE6  ;
DR   Q2K9J5, KAD_RHIEC  ;  Q98N36, KAD_RHILO  ;  Q93FE6, KAD_RHIME  ;
DR   Q7UN00, KAD_RHOBA  ;  B6IRS7, KAD_RHOCS  ;  C0ZW47, KAD_RHOE4  ;
DR   Q21TN6, KAD_RHOFD  ;  C3PP86, KAD_RICAE  ;  A8GPC9, KAD_RICAH  ;
DR   Q1RHP2, KAD_RICBR  ;  A8EZJ5, KAD_RICCK  ;  Q92GY7, KAD_RICCN  ;
DR   Q4UMQ8, KAD_RICFE  ;  Q9ZCS6, KAD_RICPR  ;  C4K2F8, KAD_RICPU  ;
DR   B0BUN9, KAD_RICRO  ;  A8GT48, KAD_RICRS  ;  Q68W99, KAD_RICTY  ;
DR   A1AVD5, KAD_RUTMC  ;  Q21II4, KAD_SACD2  ;  B5EXN0, KAD_SALA4  ;
DR   A8M508, KAD_SALAI  ;  Q57S76, KAD_SALCH  ;  B5FLJ7, KAD_SALDC  ;
DR   B5QU77, KAD_SALEP  ;  B5R612, KAD_SALG2  ;  B4T9I1, KAD_SALHS  ;
DR   B4SWY1, KAD_SALNS  ;  Q5PFK8, KAD_SALPA  ;  C0Q812, KAD_SALPC  ;
DR   B5BD44, KAD_SALPK  ;  Q2S1E4, KAD_SALRD  ;  B4TMG6, KAD_SALSV  ;
DR   P0A1V5, KAD_SALTI  ;  A4XBM5, KAD_SALTO  ;  P0A1V4, KAD_SALTY  ;
DR   P25824, KAD_SCHMA  ;  A8GAV3, KAD_SERP5  ;  A1S566, KAD_SHEAM  ;
DR   B8E732, KAD_SHEB2  ;  A3D5M6, KAD_SHEB5  ;  A6WPI0, KAD_SHEB8  ;
DR   A9L567, KAD_SHEB9  ;  Q12PB0, KAD_SHEDO  ;  Q084C4, KAD_SHEFN  ;
DR   B0TP07, KAD_SHEHH  ;  A3QF48, KAD_SHELP  ;  Q8EFF5, KAD_SHEON  ;
DR   A4Y7T5, KAD_SHEPC  ;  B8CN03, KAD_SHEPW  ;  A0KY01, KAD_SHESA  ;
DR   Q0HHZ7, KAD_SHESM  ;  Q0HU97, KAD_SHESR  ;  A1RIQ3, KAD_SHESW  ;
DR   B1KNK5, KAD_SHEWM  ;  B2U4S7, KAD_SHIB3  ;  Q325C2, KAD_SHIBS  ;
DR   Q32J54, KAD_SHIDS  ;  Q0T7B1, KAD_SHIF8  ;  Q83M40, KAD_SHIFL  ;
DR   Q3Z4S5, KAD_SHISS  ;  A6U880, KAD_SINMW  ;  Q2NV57, KAD_SODGM  ;
DR   A9FGE0, KAD_SORC5  ;  Q1GPC0, KAD_SPHAL  ;  A5V5Y1, KAD_SPHWW  ;
DR   Q5HDX9, KAD_STAAC  ;  P65201, KAD_STAAM  ;  P99062, KAD_STAAN  ;
DR   Q6GEK4, KAD_STAAR  ;  Q6G792, KAD_STAAS  ;  P65202, KAD_STAAW  ;
DR   P35141, KAD_STACA  ;  Q5HM20, KAD_STAEQ  ;  Q8CRI0, KAD_STAES  ;
DR   Q3K3U8, KAD_STRA1  ;  P65203, KAD_STRA3  ;  P65204, KAD_STRA5  ;
DR   Q82DM5, KAD_STRAW  ;  P43414, KAD_STRCO  ;  C0M6X3, KAD_STRE4  ;
DR   A8AZK4, KAD_STRGC  ;  B1W3Y6, KAD_STRGG  ;  P53398, KAD_STRGR  ;
DR   P49974, KAD_STRLI  ;  B4SI37, KAD_STRM5  ;  B2FT48, KAD_STRMK  ;
DR   Q8DS33, KAD_STRMU  ;  P69882, KAD_STRP1  ;  Q04ML5, KAD_STRP2  ;
DR   P0DB92, KAD_STRP3  ;  B5E6H6, KAD_STRP4  ;  Q5XEB4, KAD_STRP6  ;
DR   C1CAN3, KAD_STRP7  ;  Q8P2Z4, KAD_STRP8  ;  Q1JE38, KAD_STRPB  ;
DR   Q1JNZ6, KAD_STRPC  ;  Q1JJ40, KAD_STRPD  ;  Q1J8Z2, KAD_STRPF  ;
DR   A2RC35, KAD_STRPG  ;  B1I8L9, KAD_STRPI  ;  B8ZKQ1, KAD_STRPJ  ;
DR   Q48VS8, KAD_STRPM  ;  Q97SU1, KAD_STRPN  ;  P0DB93, KAD_STRPQ  ;
DR   B2IS63, KAD_STRPS  ;  B5XJ57, KAD_STRPZ  ;  Q8DRD4, KAD_STRR6  ;
DR   A4VYR4, KAD_STRS2  ;  C0ME26, KAD_STRS7  ;  P43417, KAD_STRSC  ;
DR   A3CK85, KAD_STRSV  ;  A4VSH4, KAD_STRSY  ;  Q5LXT2, KAD_STRT1  ;
DR   Q5M2D4, KAD_STRT2  ;  Q03IH2, KAD_STRTD  ;  B9DSX1, KAD_STRU0  ;
DR   C1CC27, KAD_STRZJ  ;  C1CIB8, KAD_STRZP  ;  C1CPA9, KAD_STRZT  ;
DR   A6QAE9, KAD_SULNB  ;  Q67JW4, KAD_SYMTH  ;  Q31L26, KAD_SYNE7  ;
DR   A0LIL1, KAD_SYNFM  ;  Q2JV96, KAD_SYNJA  ;  Q2JIK8, KAD_SYNJB  ;
DR   O24706, KAD_SYNP6  ;  A5GIS6, KAD_SYNPW  ;  Q7U4I1, KAD_SYNPX  ;
DR   A5GVX9, KAD_SYNR3  ;  Q0ID24, KAD_SYNS3  ;  Q3AW74, KAD_SYNS9  ;
DR   Q0AUK1, KAD_SYNWW  ;  C5BRP4, KAD_TERTT  ;  B7IHW7, KAD_THEAB  ;
DR   Q8DML4, KAD_THEEB  ;  Q47LL4, KAD_THEFY  ;  C5A5D0, KAD_THEGJ  ;
DR   A8F4T2, KAD_THELT  ;  A6LLN4, KAD_THEM4  ;  Q9X1I8, KAD_THEMA  ;
DR   Q8GGL2, KAD_THENE  ;  B9K8A7, KAD_THENN  ;  B6YVU5, KAD_THEON  ;
DR   A5IMA4, KAD_THEP1  ;  B0KCM0, KAD_THEP3  ;  B0K5R3, KAD_THEPX  ;
DR   C6A2Q1, KAD_THESM  ;  B1LBL9, KAD_THESQ  ;  Q72I25, KAD_THET2  ;
DR   Q5SHQ9, KAD_THET8  ;  Q8R7X4, KAD_THETN  ;  B5YHP1, KAD_THEYD  ;
DR   Q31DX5, KAD_THICR  ;  Q3SIR8, KAD_THIDA  ;  C4L8U2, KAD_TOLAT  ;
DR   Q73NP0, KAD_TREDE  ;  O83604, KAD_TREPA  ;  B2S3I6, KAD_TREPS  ;
DR   Q110C6, KAD_TRIEI  ;  Q83I60, KAD_TROW8  ;  Q83G05, KAD_TROWT  ;
DR   O61069, KAD_TRYBR  ;  Q0W1W4, KAD_UNCMA  ;  B1GZA3, KAD_UNCTG  ;
DR   B1AIP0, KAD_UREP2  ;  Q9PQP0, KAD_UREPA  ;  B5ZB60, KAD_UREU1  ;
DR   C5CKV9, KAD_VARPS  ;  A1WSH6, KAD_VEREI  ;  A5CXT4, KAD_VESOH  ;
DR   A5F2U0, KAD_VIBC3  ;  Q9KTB7, KAD_VIBCH  ;  C3LTN4, KAD_VIBCM  ;
DR   Q5E6Q8, KAD_VIBF1  ;  B5FBZ5, KAD_VIBFM  ;  A7MT47, KAD_VIBHB  ;
DR   Q87RH4, KAD_VIBPA  ;  B7VII5, KAD_VIBSL  ;  Q8DFM1, KAD_VIBVU  ;
DR   Q7MMR5, KAD_VIBVY  ;  Q8D227, KAD_WIGBR  ;  Q73HA6, KAD_WOLPM  ;
DR   B3CN46, KAD_WOLPP  ;  Q7M8A5, KAD_WOLSU  ;  Q5GSW4, KAD_WOLTR  ;
DR   C0R2Y9, KAD_WOLWR  ;  Q8PH23, KAD_XANAC  ;  Q3BPM9, KAD_XANC5  ;
DR   Q4UYC6, KAD_XANC8  ;  B0RP52, KAD_XANCB  ;  Q8P5P5, KAD_XANCP  ;
DR   Q2P743, KAD_XANOM  ;  Q5H4A4, KAD_XANOR  ;  A7IPP9, KAD_XANP2  ;
DR   B2I757, KAD_XYLF2  ;  Q9PGM3, KAD_XYLFA  ;  B0U1U0, KAD_XYLFM  ;
DR   Q87ES6, KAD_XYLFT  ;  A1JNB1, KAD_YERE8  ;  P43412, KAD_YEREN  ;
DR   A7FL86, KAD_YERP3  ;  Q1C4P9, KAD_YERPA  ;  B2K6Z6, KAD_YERPB  ;
DR   O69172, KAD_YERPE  ;  A9R0Q7, KAD_YERPG  ;  Q1CL27, KAD_YERPN  ;
DR   A4TPA4, KAD_YERPP  ;  Q66DP7, KAD_YERPS  ;  B1JHN1, KAD_YERPY  ;
DR   Q5NQ43, KAD_ZYMMO  ;
//
ID   2.7.4.4
DE   Nucleoside-phosphate kinase.
AN   NMP-kinase.
CA   ATP + nucleoside phosphate = ADP + nucleoside diphosphate.
CC   -!- Many nucleotides can act as acceptors.
CC   -!- Other nucleoside triphosphates can act instead of ATP.
//
ID   2.7.4.5
DE   Transferred entry: 2.7.4.14.
//
ID   2.7.4.6
DE   Nucleoside-diphosphate kinase.
AN   NDK.
AN   Nucleoside 5'-diphosphate phosphotransferase.
AN   Nucleoside diphosphokinase.
CA   ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
CC   -!- Many nucleoside diphosphates can act as acceptors.
CC   -!- Many ribo- and deoxyribonucleoside triphosphates can act as donors.
PR   PROSITE; PDOC00409;
DR   P39207, NDK1_ARATH ;  O81372, NDK1_MESCR ;  A6N0M9, NDK1_ORYSI ;
DR   Q07661, NDK1_ORYSJ ;  Q6MEA9, NDK1_PARUW ;  P47922, NDK1_PEA   ;
DR   P85929, NDK1_PSEMZ ;  P93554, NDK1_SACOF ;  Q39839, NDK1_SOYBN ;
DR   Q02254, NDK1_SPIOL ;  Q56E62, NDK1_TOBAC ;  O64903, NDK2_ARATH ;
DR   Q6MEA7, NDK2_PARUW ;  P47923, NDK2_PEA   ;  P85930, NDK2_PSEMZ ;
DR   Q01402, NDK2_SPIOL ;  Q852S5, NDK2_TOBAC ;  O49203, NDK3_ARATH ;
DR   Q13232, NDK3_HUMAN ;  Q9WV85, NDK3_MOUSE ;  P81766, NDK3_SPIOL ;
DR   Q8LAH8, NDK4_ARATH ;  Q8RXA8, NDK4_SPIOL ;  Q6DI51, NDK6_DANRE ;
DR   O75414, NDK6_HUMAN ;  O88425, NDK6_MOUSE ;  O88426, NDK6_RAT   ;
DR   B3DL53, NDK6_XENTR ;  Q5E9Y9, NDK7_BOVIN ;  Q9Y5B8, NDK7_HUMAN ;
DR   Q9QXL8, NDK7_MOUSE ;  Q9QXL7, NDK7_RAT   ;  O60361, NDK8_HUMAN ;
DR   P52174, NDKA1_BOVIN;  P70010, NDKA1_XENLA;  P52175, NDKA2_BOVIN;
DR   P70011, NDKA2_XENLA;  Q50KA9, NDKA_CANFA ;  P08879, NDKA_DROME ;
DR   Q6XI71, NDKA_DROYA ;  P47919, NDKA_FLABI ;  P15531, NDKA_HUMAN ;
DR   P15532, NDKA_MOUSE ;  Q5RC56, NDKA_PONAB ;  Q05982, NDKA_RAT   ;
DR   Q3T0Q4, NDKB_BOVIN ;  Q50KA8, NDKB_CANFA ;  P47920, NDKB_FLABI ;
DR   P22392, NDKB_HUMAN ;  P85292, NDKB_MACMG ;  P85291, NDKB_MACNO ;
DR   P85288, NDKB_MERAA ;  P85287, NDKB_MERAP ;  P85290, NDKB_MERBI ;
DR   P85281, NDKB_MERCP ;  P85286, NDKB_MERGA ;  P85285, NDKB_MERHU ;
DR   P85280, NDKB_MERME ;  P85284, NDKB_MERPA ;  P85283, NDKB_MERPO ;
DR   P85289, NDKB_MERPR ;  P85282, NDKB_MERSE ;  Q01768, NDKB_MOUSE ;
DR   Q2EN76, NDKB_PIG   ;  Q5RFH3, NDKB_PONAB ;  P19804, NDKB_RAT   ;
DR   P22887, NDKC_DICDI ;  P87355, NDKM_COLLI ;  P34093, NDKM_DICDI ;
DR   O00746, NDKM_HUMAN ;  Q9WV84, NDKM_MOUSE ;  B0C4I0, NDK_ACAM1  ;
DR   A1TM23, NDK_ACIAC  ;  Q6FEM7, NDK_ACIAD  ;  B7H073, NDK_ACIB3  ;
DR   B7I5G3, NDK_ACIB5  ;  B2I3E1, NDK_ACIBC  ;  Q1IJS7, NDK_ACIBL  ;
DR   B0VKS3, NDK_ACIBS  ;  A3M207, NDK_ACIBT  ;  B0V4U1, NDK_ACIBY  ;
DR   A5FY40, NDK_ACICJ  ;  B9MFX2, NDK_ACIET  ;  B7JC26, NDK_ACIF2  ;
DR   B5EJE9, NDK_ACIF5  ;  A1W573, NDK_ACISJ  ;  A3MZ69, NDK_ACTP2  ;
DR   B3H0J6, NDK_ACTP7  ;  B0BTA1, NDK_ACTPJ  ;  A6VMK7, NDK_ACTSZ  ;
DR   A0KJ40, NDK_AERHH  ;  Q9Y9B0, NDK_AERPE  ;  A4SP05, NDK_AERS4  ;
DR   B9JCT4, NDK_AGRRK  ;  Q8UGB6, NDK_AGRT5  ;  Q0VND6, NDK_ALCBS  ;
DR   Q0A990, NDK_ALHEH  ;  B6EGY3, NDK_ALISL  ;  B4RVH4, NDK_ALTMD  ;
DR   B8JAD8, NDK_ANAD2  ;  Q2IIB9, NDK_ANADE  ;  A7HCD8, NDK_ANADF  ;
DR   B9KGY6, NDK_ANAMF  ;  Q5P9P7, NDK_ANAMM  ;  Q2GIQ3, NDK_ANAPZ  ;
DR   B4UDP2, NDK_ANASK  ;  Q3M7K5, NDK_ANAVT  ;  O67528, NDK_AQUAE  ;
DR   A8ERJ2, NDK_ARCB4  ;  O29491, NDK_ARCFU  ;  Q5P7A9, NDK_AROAE  ;
DR   Q75DD1, NDK_ASHGO  ;  Q7Z8P9, NDK_ASPFU  ;  A8HS90, NDK_AZOC5  ;
DR   A1K3Y5, NDK_AZOSB  ;  C1DE61, NDK_AZOVD  ;  Q81SV8, NDK_BACAN  ;
DR   Q73AY0, NDK_BACC1  ;  Q81FQ4, NDK_BACCR  ;  Q63DL7, NDK_BACCZ  ;
DR   Q9KCB9, NDK_BACHD  ;  Q6HL40, NDK_BACHK  ;  Q65I26, NDK_BACLD  ;
DR   Q5WGT0, NDK_BACSK  ;  P31103, NDK_BACSU  ;  A1US76, NDK_BARBK  ;
DR   Q6G426, NDK_BARHE  ;  Q6G043, NDK_BARQU  ;  A9IS02, NDK_BART1  ;
DR   Q1LU78, NDK_BAUCH  ;  Q6MGU4, NDK_BDEBA  ;  B2II88, NDK_BEII9  ;
DR   Q2KY86, NDK_BORA1  ;  Q7WHM7, NDK_BORBR  ;  O51419, NDK_BORBU  ;
DR   Q7W6P4, NDK_BORPA  ;  A9IK55, NDK_BORPD  ;  Q7VWK7, NDK_BORPE  ;
DR   Q89MS3, NDK_BRAJA  ;  A5EIC0, NDK_BRASB  ;  A4YTA2, NDK_BRASO  ;
DR   C0ZCD6, NDK_BREBN  ;  B2S4V2, NDK_BRUA1  ;  Q2YN40, NDK_BRUA2  ;
DR   Q57E46, NDK_BRUAB  ;  A9MA67, NDK_BRUC2  ;  P48817, NDK_BRUMA  ;
DR   C0RI35, NDK_BRUMB  ;  Q8YGA4, NDK_BRUME  ;  A5VPM8, NDK_BRUO2  ;
DR   B0CL18, NDK_BRUSI  ;  Q8G1L9, NDK_BRUSU  ;  B1YR47, NDK_BURA4  ;
DR   Q1BGX7, NDK_BURCA  ;  B1JT95, NDK_BURCC  ;  A0K7T9, NDK_BURCH  ;
DR   B4EAX2, NDK_BURCJ  ;  Q0BEW4, NDK_BURCM  ;  A9AGZ3, NDK_BURM1  ;
DR   A3MK78, NDK_BURM7  ;  A2S299, NDK_BURM9  ;  Q62JW1, NDK_BURMA  ;
DR   A1V4K4, NDK_BURMS  ;  A3NVX4, NDK_BURP0  ;  Q3JRQ0, NDK_BURP1  ;
DR   A3NA57, NDK_BURP6  ;  B2JIV4, NDK_BURP8  ;  B2SXT3, NDK_BURPP  ;
DR   Q63UT6, NDK_BURPS  ;  Q39FQ6, NDK_BURS3  ;  Q2SWE7, NDK_BURTA  ;
DR   A4JEP3, NDK_BURVG  ;  Q13X25, NDK_BURXL  ;  A7ZC05, NDK_CAMC1  ;
DR   A7H051, NDK_CAMC5  ;  A0RMK4, NDK_CAMFF  ;  A7I3D2, NDK_CAMHC  ;
DR   A8FKC1, NDK_CAMJ8  ;  A7H537, NDK_CAMJD  ;  Q9PIG7, NDK_CAMJE  ;
DR   A1VY51, NDK_CAMJJ  ;  Q5HWD9, NDK_CAMJR  ;  B9KDL1, NDK_CAMLR  ;
DR   Q9UR66, NDK_CANAL  ;  Q9M7P6, NDK_CAPAN  ;  Q3AFJ7, NDK_CARHZ  ;
DR   B8GW43, NDK_CAUCN  ;  Q9A7M2, NDK_CAUCR  ;  B0SWN7, NDK_CAUSK  ;
DR   B3PDL7, NDK_CELJU  ;  O57535, NDK_CHICK  ;  A9WFJ8, NDK_CHLAA  ;
DR   Q5L6Z2, NDK_CHLAB  ;  B8G5H0, NDK_CHLAD  ;  Q3AU43, NDK_CHLCH  ;
DR   Q824M4, NDK_CHLCV  ;  Q252Y1, NDK_CHLFF  ;  B3EGU1, NDK_CHLL2  ;
DR   Q9PJP1, NDK_CHLMU  ;  B3QR32, NDK_CHLP8  ;  B3ENQ2, NDK_CHLPB  ;
DR   A1BIX9, NDK_CHLPD  ;  Q9Z7T5, NDK_CHLPN  ;  B9LKC5, NDK_CHLSY  ;
DR   B0B874, NDK_CHLT2  ;  B3QRV1, NDK_CHLT3  ;  Q3KLJ7, NDK_CHLTA  ;
DR   B0BCD9, NDK_CHLTB  ;  Q8KAZ6, NDK_CHLTE  ;  O84508, NDK_CHLTR  ;
DR   Q1QTL2, NDK_CHRSD  ;  Q7NS84, NDK_CHRVO  ;  A8AD67, NDK_CITK8  ;
DR   Q0TNY9, NDK_CLOP1  ;  Q8XIZ1, NDK_CLOPE  ;  Q0SRK8, NDK_CLOPS  ;
DR   A3DDC2, NDK_CLOTH  ;  Q90380, NDK_COLLI  ;  Q47WB6, NDK_COLP3  ;
DR   Q6NFV3, NDK_CORDI  ;  Q8FN70, NDK_COREF  ;  A4QG90, NDK_CORGB  ;
DR   Q8NN43, NDK_CORGL  ;  Q4JWU4, NDK_CORJK  ;  B1VGM4, NDK_CORU7  ;
DR   B6J7R3, NDK_COXB1  ;  B6IZM3, NDK_COXB2  ;  A9KFV6, NDK_COXBN  ;
DR   A9NDW8, NDK_COXBR  ;  Q83C71, NDK_COXBU  ;  Q0K958, NDK_CUPNH  ;
DR   Q46ZH9, NDK_CUPPJ  ;  B3R1K6, NDK_CUPTR  ;  B1WQB7, NDK_CYAA5  ;
DR   B8HUM7, NDK_CYAP4  ;  Q47BR2, NDK_DECAR  ;  Q3Z9G0, NDK_DEHE1  ;
DR   A5FS65, NDK_DEHSB  ;  Q3ZZF6, NDK_DEHSC  ;  C1D1C3, NDK_DEIDV  ;
DR   Q1IXQ0, NDK_DEIGD  ;  Q9RRJ1, NDK_DEIRA  ;  A9BMV7, NDK_DELAS  ;
DR   B8FH11, NDK_DESAA  ;  C0QBA3, NDK_DESAH  ;  B1I1P4, NDK_DESAP  ;
DR   B8IZ74, NDK_DESDA  ;  Q312A8, NDK_DESDG  ;  B8FZD1, NDK_DESHD  ;
DR   Q251Q1, NDK_DESHY  ;  A8ZWU7, NDK_DESOH  ;  Q6ALU8, NDK_DESPS  ;
DR   A4J0S4, NDK_DESRM  ;  Q729L7, NDK_DESVH  ;  B8DNF4, NDK_DESVM  ;
DR   A1VBY0, NDK_DESVV  ;  A8LIX8, NDK_DINSH  ;  A7ZPW1, NDK_ECO24  ;
DR   B7UGW4, NDK_ECO27  ;  B7MI03, NDK_ECO45  ;  B7LDB0, NDK_ECO55  ;
DR   P0A764, NDK_ECO57  ;  B5Z0Y7, NDK_ECO5E  ;  B7NRG8, NDK_ECO7I  ;
DR   B7MYF2, NDK_ECO81  ;  B7M7M2, NDK_ECO8A  ;  C4ZX93, NDK_ECOBW  ;
DR   B1XAZ3, NDK_ECODH  ;  A8A324, NDK_ECOHS  ;  A1AE56, NDK_ECOK1  ;
DR   Q0TEW7, NDK_ECOL5  ;  Q8FF53, NDK_ECOL6  ;  B1IWE3, NDK_ECOLC  ;
DR   P0A763, NDK_ECOLI  ;  B7N6A6, NDK_ECOLU  ;  B6I590, NDK_ECOSE  ;
DR   B1LNH3, NDK_ECOSM  ;  Q1R8L4, NDK_ECOUT  ;  C5BET5, NDK_EDWI9  ;
DR   Q3YQT1, NDK_EHRCJ  ;  Q2GF82, NDK_EHRCR  ;  Q5FGN1, NDK_EHRRG  ;
DR   Q5HA25, NDK_EHRRW  ;  Q8TFN0, NDK_EMENI  ;  Q8SRM7, NDK_ENCCU  ;
DR   A4WD96, NDK_ENT38  ;  A7MGV2, NDK_ENTS8  ;  Q6D272, NDK_ERWCT  ;
DR   B2VE97, NDK_ERWT9  ;  Q2N8X7, NDK_ERYLH  ;  B7LKC0, NDK_ESCF3  ;
DR   B1YI22, NDK_EXIS2  ;  C4L6N1, NDK_EXISA  ;  A7HJ26, NDK_FERNB  ;
DR   A5F9Z6, NDK_FLAJ1  ;  A6GZG2, NDK_FLAPJ  ;  Q0RPG8, NDK_FRAAA  ;
DR   B0U0L6, NDK_FRAP2  ;  Q2JDQ4, NDK_FRASC  ;  A8L1W8, NDK_FRASN  ;
DR   Q14J74, NDK_FRAT1  ;  A7ND07, NDK_FRATF  ;  Q2A2S1, NDK_FRATH  ;
DR   B2SFK0, NDK_FRATM  ;  A0Q4L4, NDK_FRATN  ;  Q0BLA4, NDK_FRATO  ;
DR   Q5NHS2, NDK_FRATT  ;  A4IZP2, NDK_FRATW  ;  B5E9D0, NDK_GEOBB  ;
DR   Q5KXU2, NDK_GEOKA  ;  B3E3P0, NDK_GEOLS  ;  Q39S70, NDK_GEOMG  ;
DR   B9M699, NDK_GEOSF  ;  Q74E54, NDK_GEOSL  ;  C6E0H6, NDK_GEOSM  ;
DR   A5GEC1, NDK_GEOUR  ;  P27950, NDK_GINCI  ;  Q7NMQ5, NDK_GLOVI  ;
DR   A9HJV3, NDK_GLUDA  ;  Q5FPN1, NDK_GLUOX  ;  Q0BQG5, NDK_GRABC  ;
DR   A0LZH1, NDK_GRAFK  ;  Q7VMD0, NDK_HAEDU  ;  Q4QM32, NDK_HAEI8  ;
DR   A5UDJ8, NDK_HAEIE  ;  A5UI22, NDK_HAEIG  ;  P43802, NDK_HAEIN  ;
DR   B8F3E4, NDK_HAEPS  ;  Q0I2G6, NDK_HAES1  ;  B0USF1, NDK_HAES2  ;
DR   Q2SDW0, NDK_HAHCH  ;  A1WXZ4, NDK_HALHL  ;  B9LPY5, NDK_HALLT  ;
DR   Q5V5M1, NDK_HALMA  ;  B0R502, NDK_HALS3  ;  P61136, NDK_HALSA  ;
DR   Q18GB1, NDK_HALWD  ;  C4K4I4, NDK_HAMD5  ;  Q17YQ6, NDK_HELAH  ;
DR   Q96559, NDK_HELAN  ;  Q7VIC9, NDK_HELHP  ;  B0TBN6, NDK_HELMI  ;
DR   B6JKD1, NDK_HELP2  ;  B5Z9W9, NDK_HELPG  ;  Q1CUW3, NDK_HELPH  ;
DR   Q9ZMN4, NDK_HELPJ  ;  B2US28, NDK_HELPS  ;  P56075, NDK_HELPY  ;
DR   A9AXD6, NDK_HERA2  ;  A4G4J8, NDK_HERAR  ;  A2BK98, NDK_HYPBU  ;
DR   Q0BZX9, NDK_HYPNA  ;  Q5QYB9, NDK_IDILO  ;  A8AAF5, NDK_IGNH4  ;
DR   A6SZX4, NDK_JANMA  ;  Q28RC3, NDK_JANSC  ;  B5XNL1, NDK_KLEP3  ;
DR   A6TCD7, NDK_KLEP7  ;  C5CGM3, NDK_KOSOT  ;  C1DD40, NDK_LARHH  ;
DR   Q1MPA2, NDK_LAWIP  ;  Q5X515, NDK_LEGPA  ;  A5IC43, NDK_LEGPC  ;
DR   Q5ZV92, NDK_LEGPH  ;  Q5WWH5, NDK_LEGPL  ;  B0S9J3, NDK_LEPBA  ;
DR   Q04P86, NDK_LEPBJ  ;  Q056E8, NDK_LEPBL  ;  B0SJT4, NDK_LEPBP  ;
DR   B1XXL7, NDK_LEPCP  ;  Q72M65, NDK_LEPIC  ;  Q8EYP5, NDK_LEPIN  ;
DR   Q92A79, NDK_LISIN  ;  C1KWM9, NDK_LISMC  ;  Q71Y86, NDK_LISMF  ;
DR   B8DBZ7, NDK_LISMH  ;  Q8Y5X4, NDK_LISMO  ;  A0AK41, NDK_LISW6  ;
DR   B9E6K9, NDK_MACCJ  ;  Q65UT5, NDK_MANSM  ;  A1TZP6, NDK_MARAV  ;
DR   Q0AQB0, NDK_MARMM  ;  A6VV02, NDK_MARMS  ;  Q11GV3, NDK_MESSB  ;
DR   Q8TQL6, NDK_METAC  ;  A7I644, NDK_METB6  ;  Q466D4, NDK_METBF  ;
DR   Q12Z94, NDK_METBU  ;  B7KYC5, NDK_METC4  ;  Q603C1, NDK_METCA  ;
DR   A9W4A4, NDK_METEP  ;  Q1H0U5, NDK_METFK  ;  Q2FRE6, NDK_METHJ  ;
DR   Q58661, NDK_METJA  ;  Q8TV10, NDK_METKA  ;  A2STK8, NDK_METLZ  ;
DR   Q8PU77, NDK_METMA  ;  A3CTF1, NDK_METMJ  ;  Q6M0I7, NDK_METMP  ;
DR   B8IH88, NDK_METNO  ;  B1ZKE5, NDK_METPB  ;  B8GKL6, NDK_METPE  ;
DR   A2SHB9, NDK_METPP  ;  B1LUB9, NDK_METRJ  ;  A5UJN0, NDK_METS3  ;
DR   B0UIS8, NDK_METS4  ;  A4YCQ4, NDK_METS5  ;  B8EJZ0, NDK_METSB  ;
DR   Q2NGM5, NDK_METST  ;  O26358, NDK_METTH  ;  B0JHT4, NDK_MICAN  ;
DR   Q5UQL3, NDK_MIMIV  ;  Q2RM94, NDK_MOOTA  ;  A0QDG6, NDK_MYCA1  ;
DR   B1MMX9, NDK_MYCA9  ;  P84283, NDK_MYCBO  ;  A1KLE1, NDK_MYCBP  ;
DR   C1AER2, NDK_MYCBT  ;  A4T2J0, NDK_MYCGI  ;  B8ZRN7, NDK_MYCLB  ;
DR   Q9CBZ0, NDK_MYCLE  ;  B2HMG5, NDK_MYCMM  ;  Q73XP1, NDK_MYCPA  ;
DR   O85501, NDK_MYCS2  ;  Q1B625, NDK_MYCSS  ;  A5U5E1, NDK_MYCTA  ;
DR   P84284, NDK_MYCTU  ;  A0PU19, NDK_MYCUA  ;  A1TC25, NDK_MYCVP  ;
DR   P15266, NDK_MYXXA  ;  Q1D6I7, NDK_MYXXD  ;  Q3IPM6, NDK_NATPD  ;
DR   B4RMG0, NDK_NEIG2  ;  P65532, NDK_NEIMA  ;  P65533, NDK_NEIMB  ;
DR   A1KUD5, NDK_NEIMF  ;  Q2GDK4, NDK_NEOSM  ;  Q9UUY8, NDK_NEUCR  ;
DR   Q0AE38, NDK_NITEC  ;  Q82XV5, NDK_NITEU  ;  Q1QLH8, NDK_NITHX  ;
DR   Q2Y6F2, NDK_NITMU  ;  Q3JCN5, NDK_NITOC  ;  A6Q200, NDK_NITSB  ;
DR   Q3SS79, NDK_NITWN  ;  Q5Z045, NDK_NOCFA  ;  A1SMD1, NDK_NOCSJ  ;
DR   B2IX22, NDK_NOSP7  ;  Q8YRP2, NDK_NOSS1  ;  Q2G9Y4, NDK_NOVAD  ;
DR   Q8EQB4, NDK_OCEIH  ;  A6X253, NDK_OCHA4  ;  B6JGK9, NDK_OLICO  ;
DR   A5CF69, NDK_ORITB  ;  B3CVG2, NDK_ORITI  ;  A6LCB6, NDK_PARD8  ;
DR   A1B2U9, NDK_PARDP  ;  A7HYF4, NDK_PARL1  ;  Q9CM17, NDK_PASMU  ;
DR   C6DBH8, NDK_PECCP  ;  Q3A2Z3, NDK_PELCD  ;  Q3B6B4, NDK_PELLD  ;
DR   B4SC92, NDK_PELPB  ;  A1AU17, NDK_PELPD  ;  A5D5U8, NDK_PELTS  ;
DR   C0QS47, NDK_PERMH  ;  B4RCP4, NDK_PHEZH  ;  Q7N710, NDK_PHOLL  ;
DR   Q6LU53, NDK_PHOPR  ;  Q6KZI4, NDK_PICTO  ;  A1VNF0, NDK_POLNA  ;
DR   B1XU72, NDK_POLNS  ;  Q12AB4, NDK_POLSJ  ;  A4SYE3, NDK_POLSQ  ;
DR   B4S573, NDK_PROA2  ;  Q6A9I7, NDK_PROAC  ;  A3PA97, NDK_PROM0  ;
DR   A2BZG4, NDK_PROM1  ;  A8G244, NDK_PROM2  ;  A2CDK0, NDK_PROM3  ;
DR   A9B9E7, NDK_PROM4  ;  A2BU01, NDK_PROM5  ;  Q31DD7, NDK_PROM9  ;
DR   Q7VEG3, NDK_PROMA  ;  B4EZT7, NDK_PROMH  ;  Q7V425, NDK_PROMM  ;
DR   Q7V3M8, NDK_PROMP  ;  A2BNH4, NDK_PROMS  ;  Q46I11, NDK_PROMT  ;
DR   Q48LZ8, NDK_PSE14  ;  Q15R52, NDK_PSEA6  ;  A6V0V6, NDK_PSEA7  ;
DR   B7UWI4, NDK_PSEA8  ;  Q02RW1, NDK_PSEAB  ;  Q59636, NDK_PSEAE  ;
DR   Q1IEI5, NDK_PSEE4  ;  Q4K6U5, NDK_PSEF5  ;  C3K1L8, NDK_PSEFS  ;
DR   Q3ID15, NDK_PSEHT  ;  A4XY36, NDK_PSEMY  ;  A5VYT1, NDK_PSEP1  ;
DR   Q3K7B2, NDK_PSEPF  ;  B0KPI3, NDK_PSEPG  ;  Q88PK1, NDK_PSEPK  ;
DR   B1JDQ6, NDK_PSEPW  ;  Q886Z4, NDK_PSESM  ;  Q4ZX27, NDK_PSEU2  ;
DR   A4VNX5, NDK_PSEU5  ;  Q4FTX1, NDK_PSYA2  ;  Q1QD23, NDK_PSYCK  ;
DR   A1SZU8, NDK_PSYIN  ;  A5WGQ5, NDK_PSYWF  ;  Q9UZ13, NDK_PYRAB  ;
DR   Q8ZWY4, NDK_PYRAE  ;  Q8U2A8, NDK_PYRFU  ;  O58429, NDK_PYRHO  ;
DR   Q5JGR7, NDK_PYRKO  ;  Q1LLI7, NDK_RALME  ;  B2U9U5, NDK_RALPJ  ;
DR   Q8Y033, NDK_RALSO  ;  B3PV77, NDK_RHIE6  ;  Q2KA61, NDK_RHIEC  ;
DR   Q1MIY5, NDK_RHIL3  ;  Q984N8, NDK_RHILO  ;  B5ZWZ6, NDK_RHILW  ;
DR   Q92QX9, NDK_RHIME  ;  C3M9D7, NDK_RHISN  ;  Q7UJK7, NDK_RHOBA  ;
DR   B6IN60, NDK_RHOCS  ;  C1A1M0, NDK_RHOE4  ;  Q21W24, NDK_RHOFD  ;
DR   C1AVK4, NDK_RHOOB  ;  Q2IX70, NDK_RHOP2  ;  Q07LG4, NDK_RHOP5  ;
DR   Q6N5C3, NDK_RHOPA  ;  Q215R4, NDK_RHOPB  ;  Q135Q2, NDK_RHOPS  ;
DR   B3Q9R4, NDK_RHOPT  ;  Q2RSC6, NDK_RHORT  ;  A3PJY2, NDK_RHOS1  ;
DR   Q3J2D0, NDK_RHOS4  ;  A4WRL4, NDK_RHOS5  ;  B9KSS4, NDK_RHOSK  ;
DR   Q0SH47, NDK_RHOSR  ;  P95653, NDK_RHOSU  ;  C3PM93, NDK_RICAE  ;
DR   A8GLZ8, NDK_RICAH  ;  A8GUR0, NDK_RICB8  ;  Q1RGT0, NDK_RICBR  ;
DR   A8EXC2, NDK_RICCK  ;  Q92JI4, NDK_RICCN  ;  Q4UN87, NDK_RICFE  ;
DR   Q9ZE91, NDK_RICPR  ;  C4K175, NDK_RICPU  ;  B0BW02, NDK_RICRO  ;
DR   A8GQL6, NDK_RICRS  ;  Q68XS9, NDK_RICTY  ;  A7NFF1, NDK_ROSCS  ;
DR   Q164H3, NDK_ROSDO  ;  A5URD5, NDK_ROSS1  ;  Q1AVT4, NDK_RUBXD  ;
DR   Q21KT7, NDK_SACD2  ;  A4F9J8, NDK_SACEN  ;  B5F1A1, NDK_SALA4  ;
DR   A9MHL2, NDK_SALAR  ;  Q57LI3, NDK_SALCH  ;  B5FR67, NDK_SALDC  ;
DR   B5R585, NDK_SALEP  ;  B5RCZ5, NDK_SALG2  ;  B4TD96, NDK_SALHS  ;
DR   B4T0Q2, NDK_SALNS  ;  Q5PNH7, NDK_SALPA  ;  C0PYM7, NDK_SALPC  ;
DR   B5BAY2, NDK_SALPK  ;  Q2S3M6, NDK_SALRD  ;  B4TR98, NDK_SALSV  ;
DR   P65535, NDK_SALTI  ;  P65534, NDK_SALTY  ;  P49740, NDK_SCHPO  ;
DR   A8GHW9, NDK_SERP5  ;  A1S552, NDK_SHEAM  ;  B8E9E1, NDK_SHEB2  ;
DR   A3D569, NDK_SHEB5  ;  A6WNX6, NDK_SHEB8  ;  A9L3Q1, NDK_SHEB9  ;
DR   Q12LK6, NDK_SHEDO  ;  Q080Q3, NDK_SHEFN  ;  B0TNY9, NDK_SHEHH  ;
DR   A3QFC8, NDK_SHELP  ;  Q8EEU0, NDK_SHEON  ;  A8H2N6, NDK_SHEPA  ;
DR   A4Y7C9, NDK_SHEPC  ;  B8CMX4, NDK_SHEPW  ;  A0KXI2, NDK_SHESA  ;
DR   A8FX96, NDK_SHESH  ;  Q0HJE6, NDK_SHESM  ;  Q0HVN6, NDK_SHESR  ;
DR   A1RJ60, NDK_SHESW  ;  B1KNJ0, NDK_SHEWM  ;  B2TXU3, NDK_SHIB3  ;
DR   Q31XX2, NDK_SHIBS  ;  Q32D44, NDK_SHIDS  ;  Q0T201, NDK_SHIF8  ;
DR   P0A765, NDK_SHIFL  ;  Q3YZ34, NDK_SHISS  ;  Q5LQP4, NDK_SILPO  ;
DR   Q1GI26, NDK_SILST  ;  A6U7K1, NDK_SINMW  ;  Q2NS36, NDK_SODGM  ;
DR   P47921, NDK_SOLLC  ;  A9GF63, NDK_SORC5  ;  Q1GSA0, NDK_SPHAL  ;
DR   A5V287, NDK_SPHWW  ;  A7X2H3, NDK_STAA1  ;  A6U1T7, NDK_STAA2  ;
DR   Q2FGX3, NDK_STAA3  ;  Q2FYG7, NDK_STAA8  ;  A5ISZ7, NDK_STAA9  ;
DR   Q2YY87, NDK_STAAB  ;  Q5HFV4, NDK_STAAC  ;  A6QH18, NDK_STAAE  ;
DR   P68869, NDK_STAAM  ;  P99068, NDK_STAAN  ;  Q6GGU2, NDK_STAAR  ;
DR   Q6G994, NDK_STAAS  ;  A8Z448, NDK_STAAT  ;  P68870, NDK_STAAU  ;
DR   Q8NWN1, NDK_STAAW  ;  B9DNV3, NDK_STACT  ;  Q5HP76, NDK_STAEQ  ;
DR   Q8CSI0, NDK_STAES  ;  Q4L6H1, NDK_STAHJ  ;  A3DMR9, NDK_STAMF  ;
DR   Q49XS3, NDK_STAS1  ;  Q3K1G0, NDK_STRA1  ;  Q8E5R4, NDK_STRA3  ;
DR   Q8E031, NDK_STRA5  ;  Q82CA0, NDK_STRAW  ;  P50589, NDK_STRCO  ;
DR   B1VXB3, NDK_STRGG  ;  B4SSW2, NDK_STRM5  ;  B2FNQ5, NDK_STRMK  ;
DR   Q04IK8, NDK_STRP2  ;  B1I8R2, NDK_STRPI  ;  P65536, NDK_STRPN  ;
DR   B2IM38, NDK_STRPS  ;  P65537, NDK_STRR6  ;  Q5M011, NDK_STRT1  ;
DR   Q5M4M4, NDK_STRT2  ;  B9DSE2, NDK_STRU0  ;  C1CGP2, NDK_STRZJ  ;
DR   C1CMQ6, NDK_STRZP  ;  C1CTL2, NDK_STRZT  ;  Q4JAV3, NDK_SULAC  ;
DR   Q30PN2, NDK_SULDN  ;  C3MZM4, NDK_SULIA  ;  C4KIV4, NDK_SULIK  ;
DR   C3MRJ9, NDK_SULIL  ;  C3MY95, NDK_SULIM  ;  C3NFS7, NDK_SULIN  ;
DR   C3N7P6, NDK_SULIY  ;  A6QBY4, NDK_SULNB  ;  Q980Q7, NDK_SULSO  ;
DR   Q976A0, NDK_SULTO  ;  Q67NR4, NDK_SYMTH  ;  P50590, NDK_SYNE7  ;
DR   Q2JVI1, NDK_SYNJA  ;  Q2JPL4, NDK_SYNJB  ;  B1XIE7, NDK_SYNP2  ;
DR   Q5N1M1, NDK_SYNP6  ;  A5GPE9, NDK_SYNPW  ;  Q7U3S1, NDK_SYNPX  ;
DR   Q0I6J3, NDK_SYNS3  ;  Q3AVV5, NDK_SYNS9  ;  Q3AGP0, NDK_SYNSC  ;
DR   P74494, NDK_SYNY3  ;  C5BLW3, NDK_TERTT  ;  B7IGM6, NDK_THEAB  ;
DR   Q9HJ59, NDK_THEAC  ;  Q8DM56, NDK_THEEB  ;  Q47MU8, NDK_THEFY  ;
DR   A6LJZ9, NDK_THEM4  ;  B0KAQ8, NDK_THEP3  ;  B0K4M4, NDK_THEPX  ;
DR   B9L159, NDK_THERP  ;  Q72GQ0, NDK_THET2  ;  Q5SLV5, NDK_THET8  ;
DR   Q8RBR5, NDK_THETN  ;  Q97BK5, NDK_THEVO  ;  Q31I08, NDK_THICR  ;
DR   Q3SL74, NDK_THIDA  ;  B8GTN8, NDK_THISH  ;  C4L7J5, NDK_TOLAT  ;
DR   O83974, NDK_TREPA  ;  B2S4P7, NDK_TREPS  ;  Q116S1, NDK_TRIEI  ;
DR   Q0W8X1, NDK_UNCMA  ;  C5CXG2, NDK_VARPS  ;  A1WE20, NDK_VEREI  ;
DR   A5F3F7, NDK_VIBC3  ;  Q9KTX4, NDK_VIBCH  ;  C3LT09, NDK_VIBCM  ;
DR   Q5E776, NDK_VIBF1  ;  B5FAW8, NDK_VIBFM  ;  A7MU38, NDK_VIBHB  ;
DR   Q87S20, NDK_VIBPA  ;  B7VJT4, NDK_VIBSL  ;  Q8DEZ5, NDK_VIBVU  ;
DR   Q7MNF4, NDK_VIBVY  ;  Q8D1Y6, NDK_WIGBR  ;  Q73FY9, NDK_WOLPM  ;
DR   B3CLT9, NDK_WOLPP  ;  Q7M7Z3, NDK_WOLSU  ;  Q5GRR9, NDK_WOLTR  ;
DR   C0R4K8, NDK_WOLWR  ;  P65538, NDK_XANAC  ;  Q3BTW6, NDK_XANC5  ;
DR   Q4UUL4, NDK_XANC8  ;  B0RT49, NDK_XANCB  ;  P65539, NDK_XANCP  ;
DR   Q2P2S9, NDK_XANOM  ;  Q5GZT2, NDK_XANOR  ;  A7IHS8, NDK_XANP2  ;
DR   B2I7V6, NDK_XYLF2  ;  Q9PG44, NDK_XYLFA  ;  B0U495, NDK_XYLFM  ;
DR   Q87B35, NDK_XYLFT  ;  P36010, NDK_YEAST  ;  A1JKR7, NDK_YERE8  ;
DR   A7FFY5, NDK_YERP3  ;  Q1C5I4, NDK_YERPA  ;  B2K9Q4, NDK_YERPB  ;
DR   Q8ZCT2, NDK_YERPE  ;  A9R806, NDK_YERPG  ;  Q1CK95, NDK_YERPN  ;
DR   A4TMU1, NDK_YERPP  ;  Q667Z5, NDK_YERPS  ;  B1JS01, NDK_YERPY  ;
DR   Q54CG9, Y2928_DICDI;
//
ID   2.7.4.7
DE   Phosphomethylpyrimidine kinase.
AN   Hydroxymethylpyrimidine phosphokinase.
CA   ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine = ADP + 4-amino-2-
CA   methyl-5-diphosphomethylpyrimidine.
DR   Q08224, THI20_YEAST;  O94265, THI21_SCHPO;  Q08975, THI21_YEAST;
DR   O94266, THI22_SCHPO;  O67772, THID_AQUAE ;  O31620, THID_BACSU ;
DR   P76422, THID_ECOLI ;  P44697, THID_HAEIN ;  Q9ZL00, THID_HELPJ ;
DR   O25515, THID_HELPY ;  P66914, THID_MYCBO ;  Q9ZBL1, THID_MYCLE ;
DR   P66913, THID_MYCTU ;  P56904, THID_RHIME ;  P55882, THID_SALTY ;
DR   P66915, THID_STAAM ;  P99124, THID_STAAN ;  Q6GEY2, THID_STAAR ;
DR   Q6G7L7, THID_STAAS ;  Q8NVH3, THID_STAAW ;  Q9ZBR6, THID_STRCO ;
DR   O85786, THID_SYNE7 ;  Q8FTH8, THIED_COREF;  Q8NQH1, THIED_CORGL;
DR   P61422, THIED_GEOSL;  Q9USL6, YJK5_SCHPO ;
//
ID   2.7.4.8
DE   Guanylate kinase.
AN   Deoxyguanylate kinase.
AN   GMP kinase.
AN   Guanosine monophosphate kinase.
CA   ATP + GMP = ADP + GDP.
CC   -!- dGMP can also act as acceptor.
CC   -!- dATP can act as donor.
PR   PROSITE; PDOC00670;
DR   Q6F7H0, KGUA_ACIAD ;  Q1IK22, KGUA_ACIBL ;  Q8UGD7, KGUA_AGRT5 ;
DR   Q0VT94, KGUA_ALCBS ;  Q0A5V3, KGUA_ALHEH ;  Q2IL45, KGUA_ANADE ;
DR   Q2GLF7, KGUA_ANAPZ ;  Q3MD38, KGUA_ANAVT ;  Q5P3M0, KGUA_AROAE ;
DR   Q2NIH1, KGUA_AYWBP ;  Q81WG7, KGUA_BACAN ;  Q732K0, KGUA_BACC1 ;
DR   Q819T6, KGUA_BACCR ;  Q636F5, KGUA_BACCZ ;  Q5L9N9, KGUA_BACFN ;
DR   Q64PY1, KGUA_BACFR ;  Q9K9Y2, KGUA_BACHD ;  Q6HEU4, KGUA_BACHK ;
DR   Q65JT0, KGUA_BACLD ;  Q5WFK3, KGUA_BACSK ;  O34328, KGUA_BACSU ;
DR   Q8A677, KGUA_BACTN ;  Q6G439, KGUA_BARHE ;  Q6G053, KGUA_BARQU ;
DR   Q1LTY3, KGUA_BAUCH ;  P60549, KGUA_BDEBA ;  Q8G813, KGUA_BIFLO ;
DR   Q7VRJ7, KGUA_BLOFL ;  Q491W5, KGUA_BLOPB ;  Q2L090, KGUA_BORA1 ;
DR   Q7WI80, KGUA_BORBR ;  Q7W6B2, KGUA_BORPA ;  Q7VXZ3, KGUA_BORPE ;
DR   P46195, KGUA_BOVIN ;  Q89MV4, KGUA_BRAJA ;  Q2YMJ2, KGUA_BRUA2 ;
DR   Q57EQ3, KGUA_BRUAB ;  P65217, KGUA_BRUME ;  P65218, KGUA_BRUSU ;
DR   P57509, KGUA_BUCAI ;  Q8K9C7, KGUA_BUCAP ;  Q89AC8, KGUA_BUCBP ;
DR   Q1BY73, KGUA_BURCA ;  Q62I00, KGUA_BURMA ;  Q3JPS9, KGUA_BURP1 ;
DR   Q63RV7, KGUA_BURPS ;  Q39IL2, KGUA_BURS3 ;  Q2SY72, KGUA_BURTA ;
DR   Q13V49, KGUA_BURXL ;  Q9PNB8, KGUA_CAMJE ;  Q5HTT7, KGUA_CAMJR ;
DR   Q3AC14, KGUA_CARHZ ;  Q9A7N9, KGUA_CAUCR ;  Q5L5M1, KGUA_CHLAB ;
DR   Q3AQL3, KGUA_CHLCH ;  Q822M8, KGUA_CHLCV ;  Q255A8, KGUA_CHLFF ;
DR   Q9PL09, KGUA_CHLMU ;  Q9Z961, KGUA_CHLPN ;  Q3KMZ2, KGUA_CHLTA ;
DR   Q8KFS5, KGUA_CHLTE ;  O84033, KGUA_CHLTR ;  Q1QSI1, KGUA_CHRSD ;
DR   Q7NRL1, KGUA_CHRVO ;  Q97ID0, KGUA_CLOAB ;  Q182S8, KGUA_CLOD6 ;
DR   Q0TPK6, KGUA_CLOP1 ;  Q8XJK8, KGUA_CLOPE ;  Q0SS73, KGUA_CLOPS ;
DR   Q895Q5, KGUA_CLOTE ;  Q47UB3, KGUA_COLP3 ;  P60550, KGUA_CORDI ;
DR   Q8FT45, KGUA_COREF ;  Q8NQ42, KGUA_CORGL ;  Q4JVH4, KGUA_CORJK ;
DR   Q83EL7, KGUA_COXBU ;  Q46YE8, KGUA_CUPPJ ;  Q11XI0, KGUA_CYTH3 ;
DR   Q479A8, KGUA_DECAR ;  Q3ZAF9, KGUA_DEHE1 ;  Q3ZWD8, KGUA_DEHSC ;
DR   Q1IW06, KGUA_DEIGD ;  Q9RS38, KGUA_DEIRA ;  Q30XT1, KGUA_DESDG ;
DR   Q24TX4, KGUA_DESHY ;  Q6AJ91, KGUA_DESPS ;  Q72DM9, KGUA_DESVH ;
DR   Q54XF2, KGUA_DICDI ;  Q8XD88, KGUA_ECO57 ;  Q0TBG1, KGUA_ECOL5 ;
DR   P60547, KGUA_ECOL6 ;  P60546, KGUA_ECOLI ;  Q1R4U3, KGUA_ECOUT ;
DR   Q3YRE2, KGUA_EHRCJ ;  Q2GHE0, KGUA_EHRCR ;  Q5FFZ9, KGUA_EHRRG ;
DR   Q5HAK7, KGUA_EHRRW ;  Q82ZD5, KGUA_ENTFA ;  Q6DB60, KGUA_ERWCT ;
DR   Q2J840, KGUA_FRASC ;  Q14GD9, KGUA_FRAT1 ;  Q2A2K6, KGUA_FRATH ;
DR   Q0BL54, KGUA_FRATO ;  Q5NEY6, KGUA_FRATT ;  Q8RHI9, KGUA_FUSNN ;
DR   Q5L0S8, KGUA_GEOKA ;  Q39T72, KGUA_GEOMG ;  P60551, KGUA_GEOSL ;
DR   Q7NK59, KGUA_GLOVI ;  Q5FS85, KGUA_GLUOX ;  Q0BPZ9, KGUA_GRABC ;
DR   Q7VKP3, KGUA_HAEDU ;  Q4QJK3, KGUA_HAEI8 ;  P44310, KGUA_HAEIN ;
DR   Q0I5L8, KGUA_HAES1 ;  Q2S8R2, KGUA_HAHCH ;  Q7VIA1, KGUA_HELHP ;
DR   Q1CUI1, KGUA_HELPH ;  Q9ZMB7, KGUA_HELPJ ;  P56103, KGUA_HELPY ;
DR   Q16774, KGUA_HUMAN ;  Q0C093, KGUA_HYPNA ;  Q5QYH9, KGUA_IDILO ;
DR   Q28PK5, KGUA_JANSC ;  Q5FJH2, KGUA_LACAC ;  Q1G9H8, KGUA_LACDA ;
DR   P60552, KGUA_LACJO ;  Q9CEE3, KGUA_LACLA ;  Q88WL7, KGUA_LACPL ;
DR   Q1WUB5, KGUA_LACS1 ;  Q38XU0, KGUA_LACSS ;  Q1MRL0, KGUA_LAWIP ;
DR   Q5X3P2, KGUA_LEGPA ;  Q5ZTZ8, KGUA_LEGPH ;  Q5WV30, KGUA_LEGPL ;
DR   Q6AF82, KGUA_LEIXX ;  Q92AI1, KGUA_LISIN ;  Q71YI9, KGUA_LISMF ;
DR   Q8Y672, KGUA_LISMO ;  Q2W9C3, KGUA_MAGSA ;  Q65RR5, KGUA_MANSM ;
DR   Q0AQC4, KGUA_MARMM ;  Q6F1S1, KGUA_MESFL ;  Q11HG8, KGUA_MESSB ;
DR   Q602T6, KGUA_METCA ;  Q1GXB9, KGUA_METFK ;  Q64520, KGUA_MOUSE ;
DR   P0A5I5, KGUA_MYCBO ;  Q2SSR8, KGUA_MYCCT ;  Q9KX62, KGUA_MYCGA ;
DR   P47353, KGUA_MYCGE ;  Q601H3, KGUA_MYCH2 ;  Q4A8L2, KGUA_MYCH7 ;
DR   Q4AAI1, KGUA_MYCHJ ;  Q9CCQ7, KGUA_MYCLE ;  Q6KH87, KGUA_MYCMO ;
DR   Q6MU25, KGUA_MYCMS ;  P60553, KGUA_MYCPA ;  Q8EVJ9, KGUA_MYCPE ;
DR   P75526, KGUA_MYCPN ;  Q98PN5, KGUA_MYCPU ;  Q4A6S7, KGUA_MYCS5 ;
DR   Q1B9F6, KGUA_MYCSS ;  P0A5I4, KGUA_MYCTU ;  Q1D3A6, KGUA_MYXXD ;
DR   Q5F775, KGUA_NEIG1 ;  Q9JT96, KGUA_NEIMA ;  Q9JYB5, KGUA_NEIMB ;
DR   Q2GD44, KGUA_NEOSM ;  Q82SQ3, KGUA_NITEU ;  Q1QKV7, KGUA_NITHX ;
DR   Q2YD10, KGUA_NITMU ;  Q3JBT3, KGUA_NITOC ;  Q3SRZ7, KGUA_NITWN ;
DR   Q5YTM7, KGUA_NOCFA ;  Q8Z0I7, KGUA_NOSS1 ;  Q2G9M5, KGUA_NOVAD ;
DR   Q8ER28, KGUA_OCEIH ;  P60554, KGUA_ONYPE ;  Q6MDG3, KGUA_PARUW ;
DR   P57888, KGUA_PASMU ;  Q3A523, KGUA_PELCD ;  Q3B204, KGUA_PELLD ;
DR   Q4FMR1, KGUA_PELUB ;  Q7N9P2, KGUA_PHOLL ;  Q6LVP5, KGUA_PHOPR ;
DR   P31006, KGUA_PIG   ;  Q12DV7, KGUA_POLSJ ;  Q7MWS7, KGUA_PORGI ;
DR   Q6A8H6, KGUA_PROAC ;  Q31C67, KGUA_PROM9 ;  Q7VDB6, KGUA_PROMA ;
DR   P60555, KGUA_PROMM ;  Q7V2K9, KGUA_PROMP ;  Q46GV6, KGUA_PROMT ;
DR   Q48Q15, KGUA_PSE14 ;  Q15Z10, KGUA_PSEA6 ;  Q9HTM2, KGUA_PSEAE ;
DR   Q4K3R4, KGUA_PSEF5 ;  Q3IJH8, KGUA_PSEHT ;  Q3K4L8, KGUA_PSEPF ;
DR   Q88C87, KGUA_PSEPK ;  Q88BE2, KGUA_PSESM ;  Q4ZZY8, KGUA_PSEU2 ;
DR   Q4FQY7, KGUA_PSYA2 ;  Q1Q973, KGUA_PSYCK ;  Q1LQ34, KGUA_RALME ;
DR   Q8XXF9, KGUA_RALSO ;  Q2KA85, KGUA_RHIEC ;  Q1MJ02, KGUA_RHIL3 ;
DR   Q984S9, KGUA_RHILO ;  Q92QZ2, KGUA_RHIME ;  Q7UP92, KGUA_RHOBA ;
DR   Q21TP7, KGUA_RHOFD ;  Q2IX83, KGUA_RHOP2 ;  P60556, KGUA_RHOPA ;
DR   Q215S7, KGUA_RHOPB ;  Q135N9, KGUA_RHOPS ;  Q2RXB1, KGUA_RHORT ;
DR   Q3J2A5, KGUA_RHOS4 ;  Q0S0L7, KGUA_RHOSR ;  Q1RK99, KGUA_RICBR ;
DR   Q92GC9, KGUA_RICCN ;  Q4UK55, KGUA_RICFE ;  Q9ZCH7, KGUA_RICPR ;
DR   Q68VY3, KGUA_RICTY ;  Q166A7, KGUA_ROSDO ;  Q1AVZ3, KGUA_RUBXD ;
DR   Q21EC9, KGUA_SACD2 ;  Q57I92, KGUA_SALCH ;  Q5PC40, KGUA_SALPA ;
DR   Q2S6J5, KGUA_SALRD ;  Q8Z2H9, KGUA_SALTI ;  Q9X6M5, KGUA_SALTY ;
DR   Q9P6I5, KGUA_SCHPO ;  Q12IL8, KGUA_SHEDO ;  Q088T7, KGUA_SHEFN ;
DR   Q8EJU6, KGUA_SHEON ;  Q0HE40, KGUA_SHESM ;  Q0HZX1, KGUA_SHESR ;
DR   Q7WZE5, KGUA_SHEVD ;  Q31UQ6, KGUA_SHIBS ;  Q329K8, KGUA_SHIDS ;
DR   P60548, KGUA_SHIFL ;  Q3YW11, KGUA_SHISS ;  Q5LS25, KGUA_SILPO ;
DR   Q1GH67, KGUA_SILST ;  Q2NQS9, KGUA_SODGM ;  Q1GNB4, KGUA_SPHAL ;
DR   Q2FHM9, KGUA_STAA3 ;  Q2G1U0, KGUA_STAA8 ;  Q2YXF9, KGUA_STAAB ;
DR   Q5HGM3, KGUA_STAAC ;  P65219, KGUA_STAAM ;  P99176, KGUA_STAAN ;
DR   Q6GHM6, KGUA_STAAR ;  Q6GA04, KGUA_STAAS ;  Q8NX22, KGUA_STAAW ;
DR   P0C0M8, KGUA_STAEP ;  Q5HPY1, KGUA_STAEQ ;  P0C0M9, KGUA_STAES ;
DR   Q4L5R1, KGUA_STAHJ ;  Q49WZ1, KGUA_STAS1 ;  Q3K368, KGUA_STRA1 ;
DR   P65220, KGUA_STRA3 ;  P65221, KGUA_STRA5 ;  Q827Q3, KGUA_STRAW ;
DR   Q9KXS0, KGUA_STRCO ;  Q8GAU4, KGUA_STRKA ;  Q8DVK6, KGUA_STRMU ;
DR   Q99YM5, KGUA_STRP1 ;  P0DB94, KGUA_STRP3 ;  Q5XAP1, KGUA_STRP6 ;
DR   P65223, KGUA_STRP8 ;  Q1JAJ4, KGUA_STRPB ;  Q1JKP6, KGUA_STRPC ;
DR   Q1JFN7, KGUA_STRPD ;  Q1J5I6, KGUA_STRPF ;  Q48S18, KGUA_STRPM ;
DR   Q97PA3, KGUA_STRPN ;  P0DB95, KGUA_STRPQ ;  Q8DNR5, KGUA_STRR6 ;
DR   Q5LYX1, KGUA_STRT1 ;  Q5M3I4, KGUA_STRT2 ;  Q30PL1, KGUA_SULDN ;
DR   Q67PR9, KGUA_SYMTH ;  Q2LQ62, KGUA_SYNAS ;  Q8KPQ7, KGUA_SYNE7 ;
DR   Q2JQB9, KGUA_SYNJA ;  Q2JQ59, KGUA_SYNJB ;  Q5N570, KGUA_SYNP6 ;
DR   Q7U570, KGUA_SYNPX ;  Q0I868, KGUA_SYNS3 ;  Q3AWM1, KGUA_SYNS9 ;
DR   Q3ALX6, KGUA_SYNSC ;  Q0AXK8, KGUA_SYNWW ;  P72648, KGUA_SYNY3 ;
DR   Q8DMQ7, KGUA_THEEB ;  Q47R17, KGUA_THEFY ;  Q9X215, KGUA_THEMA ;
DR   Q72ID5, KGUA_THET2 ;  Q5SI18, KGUA_THET8 ;  Q8R9S6, KGUA_THETN ;
DR   Q31DP7, KGUA_THICR ;  Q3SLI4, KGUA_THIDA ;  Q110R6, KGUA_TRIEI ;
DR   Q83HT8, KGUA_TROW8 ;  Q83GE3, KGUA_TROWT ;  Q9PQS9, KGUA_UREPA ;
DR   Q9KNM4, KGUA_VIBCH ;  Q5E8P5, KGUA_VIBF1 ;  Q87TA9, KGUA_VIBPA ;
DR   Q8DDV6, KGUA_VIBVU ;  Q7MPW9, KGUA_VIBVY ;  Q8D2E8, KGUA_WIGBR ;
DR   Q73HV1, KGUA_WOLPM ;  Q7MAK5, KGUA_WOLSU ;  Q5GS56, KGUA_WOLTR ;
DR   Q8PH65, KGUA_XANAC ;  Q3BPS0, KGUA_XANC5 ;  Q4UY41, KGUA_XANC8 ;
DR   Q8P5T7, KGUA_XANCP ;  Q2P6N0, KGUA_XANOM ;  Q5H3S2, KGUA_XANOR ;
DR   Q9PD76, KGUA_XYLFA ;  Q87DG5, KGUA_XYLFT ;  P15454, KGUA_YEAST ;
DR   Q1C258, KGUA_YERPA ;  Q8ZJQ2, KGUA_YERPE ;  Q1CCZ3, KGUA_YERPN ;
DR   Q66GE5, KGUA_YERPS ;  Q5NQE8, KGUA_ZYMMO ;
//
ID   2.7.4.9
DE   dTMP kinase.
AN   Thymidylate kinase.
AN   Thymidylic acid kinase.
AN   TMPK.
CA   ATP + dTMP = ADP + dTDP.
PR   PROSITE; PDOC01034;
DR   Q9UXG7, KTHY1_SULSO;  Q975E6, KTHY1_SULTO;  P58157, KTHY2_SULSO;
DR   Q970Q8, KTHY2_SULTO;  A4ZU96, KTHY_ABVP  ;  B0C3N6, KTHY_ACAM1 ;
DR   A9NEH3, KTHY_ACHLI ;  A1TSN1, KTHY_ACIAC ;  Q6F9B5, KTHY_ACIAD ;
DR   B7GYE0, KTHY_ACIB3 ;  B7I585, KTHY_ACIB5 ;  B2HWQ7, KTHY_ACIBC ;
DR   B0VTL6, KTHY_ACIBS ;  A3M7Q1, KTHY_ACIBT ;  B0VCV4, KTHY_ACIBY ;
DR   A1W6N2, KTHY_ACISJ ;  A3N3B3, KTHY_ACTP2 ;  B3GZ69, KTHY_ACTP7 ;
DR   B0BSY9, KTHY_ACTPJ ;  A6VQH1, KTHY_ACTSZ ;  A0KKH9, KTHY_AERHH ;
DR   Q9YA48, KTHY_AERPE ;  Q8UFA0, KTHY_AGRT5 ;  B2UN87, KTHY_AKKM8 ;
DR   Q0VQM6, KTHY_ALCBS ;  Q0A8S2, KTHY_ALHEH ;  B6EJ04, KTHY_ALISL ;
DR   B4S1N2, KTHY_ALTMD ;  B9KHK6, KTHY_ANAMF ;  Q5PBS1, KTHY_ANAMM ;
DR   Q2GLN0, KTHY_ANAPZ ;  Q3MBQ2, KTHY_ANAVT ;  B7GFF9, KTHY_ANOFW ;
DR   O67099, KTHY_AQUAE ;  A8ETF2, KTHY_ARCB4 ;  O30175, KTHY_ARCFU ;
DR   P42490, KTHY_ASFB7 ;  P0C8F9, KTHY_ASFK5 ;  P0C8G1, KTHY_ASFP4 ;
DR   P0C8G2, KTHY_ASFWA ;  Q2NIY4, KTHY_AYWBP ;  A7Z0F1, KTHY_BACA2 ;
DR   C3P9H5, KTHY_BACAA ;  C3LJ02, KTHY_BACAC ;  A0R8A3, KTHY_BACAH ;
DR   Q81W11, KTHY_BACAN ;  Q73FH8, KTHY_BACC1 ;  B7ISU0, KTHY_BACC2 ;
DR   C1ES32, KTHY_BACC3 ;  B7HIJ8, KTHY_BACC4 ;  B7HPU1, KTHY_BACC7 ;
DR   A7GJU2, KTHY_BACCN ;  B9IZB3, KTHY_BACCQ ;  Q81JB5, KTHY_BACCR ;
DR   Q63HH8, KTHY_BACCZ ;  Q9KGL9, KTHY_BACHD ;  Q6HPY6, KTHY_BACHK ;
DR   Q65PJ3, KTHY_BACLD ;  A8F8Z5, KTHY_BACP2 ;  Q5WLY2, KTHY_BACSK ;
DR   P37537, KTHY_BACSU ;  A9VN43, KTHY_BACWK ;  Q6G5D6, KTHY_BARHE ;
DR   Q6FZU8, KTHY_BARQU ;  Q1LT42, KTHY_BAUCH ;  Q6MP28, KTHY_BDEBA ;
DR   A0ZZR0, KTHY_BIFAA ;  B3DUA1, KTHY_BIFLD ;  Q8G6Z6, KTHY_BIFLO ;
DR   B7GT80, KTHY_BIFLS ;  Q7VR23, KTHY_BLOFL ;  Q492Q6, KTHY_BLOPB ;
DR   Q7WJ63, KTHY_BORBR ;  Q7WA31, KTHY_BORPA ;  A9INL0, KTHY_BORPD ;
DR   Q7VXD2, KTHY_BORPE ;  C0R1X1, KTHY_BRAHW ;  Q89LM5, KTHY_BRAJA ;
DR   A5EJ24, KTHY_BRASB ;  A4YUL6, KTHY_BRASO ;  B2S5K6, KTHY_BRUA1 ;
DR   A9MB09, KTHY_BRUC2 ;  C0RIW8, KTHY_BRUMB ;  Q8YH15, KTHY_BRUME ;
DR   A5VQD7, KTHY_BRUO2 ;  B0CGE4, KTHY_BRUSI ;  Q8G0U3, KTHY_BRUSU ;
DR   P57434, KTHY_BUCAI ;  Q8K9J3, KTHY_BUCAP ;  P59500, KTHY_BUCBP ;
DR   B1YRL3, KTHY_BURA4 ;  Q1BH55, KTHY_BURCA ;  B1JTS0, KTHY_BURCC ;
DR   A0K817, KTHY_BURCH ;  B4EBJ2, KTHY_BURCJ ;  Q0BEN7, KTHY_BURCM ;
DR   A3MKF7, KTHY_BURM7 ;  A2SBK1, KTHY_BURM9 ;  Q62JN9, KTHY_BURMA ;
DR   A1V4T2, KTHY_BURMS ;  A3NW63, KTHY_BURP0 ;  Q3JRG5, KTHY_BURP1 ;
DR   A3NAE5, KTHY_BURP6 ;  B2JGP7, KTHY_BURP8 ;  B2T436, KTHY_BURPP ;
DR   Q63V08, KTHY_BURPS ;  Q39FH9, KTHY_BURS3 ;  Q2SWM4, KTHY_BURTA ;
DR   A4JEW8, KTHY_BURVG ;  Q13YY3, KTHY_BURXL ;  Q22018, KTHY_CAEEL ;
DR   A8MB58, KTHY_CALMQ ;  A4XHH4, KTHY_CALS8 ;  A7ZDK0, KTHY_CAMC1 ;
DR   A7GYH0, KTHY_CAMC5 ;  A0RPD2, KTHY_CAMFF ;  A7I1U4, KTHY_CAMHC ;
DR   A8FLH9, KTHY_CAMJ8 ;  A7H476, KTHY_CAMJD ;  Q9PPF3, KTHY_CAMJE ;
DR   A1VZB4, KTHY_CAMJJ ;  Q5HV26, KTHY_CAMJR ;  B9KG87, KTHY_CAMLR ;
DR   Q8V2K9, KTHY_CAMPM ;  Q8QQ21, KTHY_CAMPS ;  Q3AG12, KTHY_CARHZ ;
DR   Q9RQJ9, KTHY_CAUCR ;  Q5L5Y4, KTHY_CHLAB ;  Q3AS37, KTHY_CHLCH ;
DR   Q823B7, KTHY_CHLCV ;  Q254L6, KTHY_CHLFF ;  B3EDD6, KTHY_CHLL2 ;
DR   Q9PKK5, KTHY_CHLMU ;  B3QP81, KTHY_CHLP8 ;  A1BGY2, KTHY_CHLPD ;
DR   Q9Z8R5, KTHY_CHLPN ;  B0B9T8, KTHY_CHLT2 ;  Q3KMH4, KTHY_CHLTA ;
DR   B0BBG8, KTHY_CHLTB ;  Q8KCU7, KTHY_CHLTE ;  O84191, KTHY_CHLTR ;
DR   Q1QX49, KTHY_CHRSD ;  Q7NRQ7, KTHY_CHRVO ;  A8AHX4, KTHY_CITK8 ;
DR   A5CPG8, KTHY_CLAM3 ;  B0RAE3, KTHY_CLAMS ;  A6LPM3, KTHY_CLOB8 ;
DR   A0Q3M5, KTHY_CLONN ;  Q482J5, KTHY_COLP3 ;  B5Y7S6, KTHY_COPPD ;
DR   Q83E35, KTHY_COXBU ;  Q0KBC0, KTHY_CUPNH ;  Q471X9, KTHY_CUPPJ ;
DR   B3R181, KTHY_CUPTR ;  Q8QMQ7, KTHY_CWPXB ;  Q80DS7, KTHY_CWPXG ;
DR   B8HXT9, KTHY_CYAP4 ;  Q47DZ5, KTHY_DECAR ;  Q3Z8D9, KTHY_DEHE1 ;
DR   A5FR84, KTHY_DEHSB ;  Q3ZXD8, KTHY_DEHSC ;  Q9RY40, KTHY_DEIRA ;
DR   C6BUG6, KTHY_DESAD ;  C0QI33, KTHY_DESAH ;  B1I165, KTHY_DESAP ;
DR   B8J2G0, KTHY_DESDA ;  Q30YW1, KTHY_DESDG ;  C4XNX1, KTHY_DESMR ;
DR   A8ZXL3, KTHY_DESOH ;  Q6AJE2, KTHY_DESPS ;  A4J0K6, KTHY_DESRM ;
DR   Q72A57, KTHY_DESVH ;  B8DN41, KTHY_DESVM ;  A1VCE6, KTHY_DESVV ;
DR   Q54GN2, KTHY_DICDI ;  A5EXE3, KTHY_DICNV ;  A8LRW0, KTHY_DINSH ;
DR   A7ZKK1, KTHY_ECO24 ;  B7UPB4, KTHY_ECO27 ;  B7MJ85, KTHY_ECO45 ;
DR   B7LG31, KTHY_ECO55 ;  Q8X8H6, KTHY_ECO57 ;  B5YVW6, KTHY_ECO5E ;
DR   B7NKI2, KTHY_ECO7I ;  B7MTM8, KTHY_ECO81 ;  B7LX32, KTHY_ECO8A ;
DR   C4ZS38, KTHY_ECOBW ;  B1XA08, KTHY_ECODH ;  A7ZZ55, KTHY_ECOHS ;
DR   A1A9Z2, KTHY_ECOK1 ;  Q0TIX6, KTHY_ECOL5 ;  Q8FIN9, KTHY_ECOL6 ;
DR   B1IUG7, KTHY_ECOLC ;  P0A720, KTHY_ECOLI ;  B7NAX6, KTHY_ECOLU ;
DR   B6I9H5, KTHY_ECOSE ;  B1LI47, KTHY_ECOSM ;  Q1RD57, KTHY_ECOUT ;
DR   Q8JL72, KTHY_ECTVM ;  C5B8G5, KTHY_EDWI9 ;  Q3YR44, KTHY_EHRCJ ;
DR   Q2GHN3, KTHY_EHRCR ;  Q5FG91, KTHY_EHRRG ;  Q5HAD6, KTHY_EHRRW ;
DR   A4W9B2, KTHY_ENT38 ;  Q830L6, KTHY_ENTFA ;  A7MFR1, KTHY_ENTS8 ;
DR   Q6D683, KTHY_ERWCT ;  B2VDK3, KTHY_ERWT9 ;  B7LT40, KTHY_ESCF3 ;
DR   B1YGD3, KTHY_EXIS2 ;  C4KZW9, KTHY_EXISA ;  A7HKW8, KTHY_FERNB ;
DR   B0S2F7, KTHY_FINM2 ;  B0TWY5, KTHY_FRAP2 ;  Q14JV8, KTHY_FRAT1 ;
DR   A7NE29, KTHY_FRATF ;  Q2A1V7, KTHY_FRATH ;  B2SF22, KTHY_FRATM ;
DR   A0Q893, KTHY_FRATN ;  Q0BKK1, KTHY_FRATO ;  Q5NIF5, KTHY_FRATT ;
DR   A4IW74, KTHY_FRATW ;  B5E9M9, KTHY_GEOBB ;  Q5L3W9, KTHY_GEOKA ;
DR   B3E2K5, KTHY_GEOLS ;  B9M910, KTHY_GEOSF ;  Q74AX0, KTHY_GEOSL ;
DR   C6E2H4, KTHY_GEOSM ;  C5D352, KTHY_GEOSW ;  A4IJA6, KTHY_GEOTN ;
DR   A5G696, KTHY_GEOUR ;  Q7NMT7, KTHY_GLOVI ;  Q5FUU6, KTHY_GLUOX ;
DR   Q7VKH4, KTHY_HAEDU ;  A5UA33, KTHY_HAEIE ;  A5UGW7, KTHY_HAEIG ;
DR   P44719, KTHY_HAEIN ;  B8F7G0, KTHY_HAEPS ;  Q0I5J0, KTHY_HAES1 ;
DR   B0URV9, KTHY_HAES2 ;  Q2SK46, KTHY_HAHCH ;  A1WSY9, KTHY_HALHL ;
DR   B9LQ28, KTHY_HALLT ;  Q5UXM3, KTHY_HALMA ;  B8CZT1, KTHY_HALOH ;
DR   B0R6P3, KTHY_HALS3 ;  Q9HNV4, KTHY_HALSA ;  C4K3R2, KTHY_HAMD5 ;
DR   Q17V96, KTHY_HELAH ;  Q7VGF9, KTHY_HELHP ;  B6JNX2, KTHY_HELP2 ;
DR   B5Z993, KTHY_HELPG ;  Q1CRB6, KTHY_HELPH ;  Q9ZJE5, KTHY_HELPJ ;
DR   B2UVL9, KTHY_HELPS ;  O26009, KTHY_HELPY ;  A9AV71, KTHY_HERA2 ;
DR   A4G4Y1, KTHY_HERAR ;  P23919, KTHY_HUMAN ;  Q5QZ32, KTHY_IDILO ;
DR   Q91FS1, KTHY_IIV6  ;  A6SZH9, KTHY_JANMA ;  Q28SW8, KTHY_JANSC ;
DR   B5XXH2, KTHY_KLEP3 ;  A6T7F8, KTHY_KLEP7 ;  C5CHP2, KTHY_KOSOT ;
DR   Q5FM02, KTHY_LACAC ;  Q03SS3, KTHY_LACBA ;  Q035W9, KTHY_LACC3 ;
DR   B3W9Y8, KTHY_LACCB ;  Q1G923, KTHY_LACDA ;  Q048W8, KTHY_LACDB ;
DR   B2GAE1, KTHY_LACF3 ;  A8YTF9, KTHY_LACH4 ;  Q74KZ7, KTHY_LACJO ;
DR   Q9CIG4, KTHY_LACLA ;  A2RIC4, KTHY_LACLM ;  Q031S3, KTHY_LACLS ;
DR   Q88YP6, KTHY_LACPL ;  A5VIC6, KTHY_LACRD ;  B2G5V3, KTHY_LACRJ ;
DR   Q1WSU7, KTHY_LACS1 ;  Q38YT6, KTHY_LACSS ;  Q1MQB3, KTHY_LAWIP ;
DR   Q5X5G6, KTHY_LEGPA ;  A5IBP1, KTHY_LEGPC ;  Q5ZVP1, KTHY_LEGPH ;
DR   Q5WWU9, KTHY_LEGPL ;  Q6AGT5, KTHY_LEIXX ;  Q04UJ2, KTHY_LEPBJ ;
DR   Q04YY2, KTHY_LEPBL ;  Q72NL9, KTHY_LEPIC ;  Q8F7Y6, KTHY_LEPIN ;
DR   B1MVT4, KTHY_LEUCK ;  Q03ZG6, KTHY_LEUMM ;  Q927E8, KTHY_LISIN ;
DR   C1KZP7, KTHY_LISMC ;  Q71W79, KTHY_LISMF ;  B8DAU8, KTHY_LISMH ;
DR   Q8Y3Y6, KTHY_LISMO ;  A0AM28, KTHY_LISW6 ;  A0L8T5, KTHY_MAGSM ;
DR   Q65V34, KTHY_MANSM ;  A6VXL0, KTHY_MARMS ;  Q6F0E1, KTHY_MESFL ;
DR   Q11HZ9, KTHY_MESSB ;  A6UTV9, KTHY_META3 ;  Q8THS9, KTHY_METAC ;
DR   Q46DH6, KTHY_METBF ;  Q12VF9, KTHY_METBU ;  Q606M0, KTHY_METCA ;
DR   Q1H169, KTHY_METFK ;  Q2FS90, KTHY_METHJ ;  Q57741, KTHY_METJA ;
DR   Q8TZ38, KTHY_METKA ;  A2ST45, KTHY_METLZ ;  A4FXE4, KTHY_METM5 ;
DR   A9AAR4, KTHY_METM6 ;  A6VFY2, KTHY_METM7 ;  Q8PXV5, KTHY_METMA ;
DR   A3CVV0, KTHY_METMJ ;  Q6LYF7, KTHY_METMP ;  A5UKJ7, KTHY_METS3 ;
DR   A4YIC4, KTHY_METS5 ;  Q2NHE3, KTHY_METST ;  O27793, KTHY_METTH ;
DR   A6UP44, KTHY_METVS ;  P97930, KTHY_MOUSE ;  A5IZC6, KTHY_MYCAP ;
DR   Q2STA4, KTHY_MYCCT ;  Q7NAD7, KTHY_MYCGA ;  P47252, KTHY_MYCGE ;
DR   Q601T1, KTHY_MYCH2 ;  Q4A8A6, KTHY_MYCH7 ;  Q4AA79, KTHY_MYCHJ ;
DR   Q6KIL4, KTHY_MYCMO ;  Q6MUI5, KTHY_MYCMS ;  Q8EUV4, KTHY_MYCPE ;
DR   P75106, KTHY_MYCPN ;  Q98RF7, KTHY_MYCPU ;  Q4A6Z8, KTHY_MYCS5 ;
DR   O05891, KTHY_MYCTU ;  Q3IRB3, KTHY_NATPD ;  B9L9C1, KTHY_NAUPA ;
DR   Q5F9Z5, KTHY_NEIG1 ;  B4RJR3, KTHY_NEIG2 ;  Q9JVE7, KTHY_NEIMA ;
DR   Q9K0D9, KTHY_NEIMB ;  A1KST1, KTHY_NEIMF ;  Q2GDL6, KTHY_NEOSM ;
DR   Q0AIL5, KTHY_NITEC ;  Q82SW5, KTHY_NITEU ;  Q1QLT8, KTHY_NITHX ;
DR   Q2Y981, KTHY_NITMU ;  Q3SSL6, KTHY_NITWN ;  B2IZE7, KTHY_NOSP7 ;
DR   Q8YN62, KTHY_NOSS1 ;  Q8EU53, KTHY_OCEIH ;  Q04E53, KTHY_OENOB ;
DR   B6JEC6, KTHY_OLICO ;  Q7WSH2, KTHY_ONYPE ;  A5CDS9, KTHY_ORITB ;
DR   B3CR61, KTHY_ORITI ;  Q6MCA2, KTHY_PARUW ;  Q9CKE9, KTHY_PASMU ;
DR   C6DKS8, KTHY_PECCP ;  Q03E60, KTHY_PEDPA ;  Q3A3X3, KTHY_PELCD ;
DR   Q3B3B1, KTHY_PELLD ;  B4SAG3, KTHY_PELPB ;  A1APK9, KTHY_PELPD ;
DR   A5D690, KTHY_PELTS ;  Q7N391, KTHY_PHOLL ;  Q6LSW5, KTHY_PHOPR ;
DR   Q6L016, KTHY_PICTO ;  Q12AK6, KTHY_POLSJ ;  B4S8U3, KTHY_PROA2 ;
DR   Q6AB62, KTHY_PROAC ;  A3PAJ7, KTHY_PROM0 ;  A2BZV6, KTHY_PROM1 ;
DR   A8G2D5, KTHY_PROM2 ;  A2CD19, KTHY_PROM3 ;  A9BCY7, KTHY_PROM4 ;
DR   A2BUA6, KTHY_PROM5 ;  Q31D51, KTHY_PROM9 ;  Q7VE61, KTHY_PROMA ;
DR   Q7V4G2, KTHY_PROMM ;  Q7V3E6, KTHY_PROMP ;  A2BNS4, KTHY_PROMS ;
DR   Q46HP4, KTHY_PROMT ;  A4SF00, KTHY_PROVI ;  Q48L36, KTHY_PSE14 ;
DR   A6V3D6, KTHY_PSEA7 ;  B7V167, KTHY_PSEA8 ;  Q02PC5, KTHY_PSEAB ;
DR   Q9HZN8, KTHY_PSEAE ;  Q1ICY2, KTHY_PSEE4 ;  Q4KFR2, KTHY_PSEF5 ;
DR   C3K0M9, KTHY_PSEFS ;  Q3IHC1, KTHY_PSEHT ;  A4XST1, KTHY_PSEMY ;
DR   A5W709, KTHY_PSEP1 ;  Q3K8L5, KTHY_PSEPF ;  B0KF60, KTHY_PSEPG ;
DR   B1J4Z5, KTHY_PSEPW ;  Q87YH1, KTHY_PSESM ;  Q4ZVX2, KTHY_PSEU2 ;
DR   A4VMR6, KTHY_PSEU5 ;  A5WBP5, KTHY_PSYWF ;  Q9V1E9, KTHY_PYRAB ;
DR   Q8ZY35, KTHY_PYRAE ;  A3MSE7, KTHY_PYRCJ ;  Q8U071, KTHY_PYRFU ;
DR   O59366, KTHY_PYRHO ;  Q5JH21, KTHY_PYRKO ;  Q6RZD4, KTHY_RABPU ;
DR   Q1LMB9, KTHY_RALME ;  B2UBZ3, KTHY_RALPJ ;  Q8XYH4, KTHY_RALSO ;
DR   Q98MV4, KTHY_RHILO ;  Q92PW7, KTHY_RHIME ;  Q7UIM1, KTHY_RHOBA ;
DR   Q21W76, KTHY_RHOFD ;  Q6N643, KTHY_RHOPA ;  Q214D4, KTHY_RHOPB ;
DR   B3QKH1, KTHY_RHOPT ;  A3PLT9, KTHY_RHOS1 ;  Q3J0G1, KTHY_RHOS4 ;
DR   B9KKV1, KTHY_RHOSK ;  C3PLG0, KTHY_RICAE ;  A8GPJ0, KTHY_RICAH ;
DR   A8GXQ1, KTHY_RICB8 ;  Q1RJZ6, KTHY_RICBR ;  A8EZQ1, KTHY_RICCK ;
DR   Q92GS5, KTHY_RICCN ;  Q4UMX3, KTHY_RICFE ;  A8F2H5, KTHY_RICM5 ;
DR   Q9ZCN9, KTHY_RICPR ;  C4K2K8, KTHY_RICPU ;  B0BUU8, KTHY_RICRO ;
DR   A8GTB0, KTHY_RICRS ;  Q68W53, KTHY_RICTY ;  A7NQB4, KTHY_ROSCS ;
DR   A5UY90, KTHY_ROSS1 ;  A1AVP9, KTHY_RUTMC ;  B5F907, KTHY_SALA4 ;
DR   A9MGB6, KTHY_SALAR ;  Q57QF5, KTHY_SALCH ;  B5FKA7, KTHY_SALDC ;
DR   B5QXD6, KTHY_SALEP ;  B5RBA2, KTHY_SALG2 ;  B4TFH5, KTHY_SALHS ;
DR   B4T332, KTHY_SALNS ;  Q5PGT4, KTHY_SALPA ;  A9N5K6, KTHY_SALPB ;
DR   C0Q792, KTHY_SALPC ;  B5BAH5, KTHY_SALPK ;  B4TTH0, KTHY_SALSV ;
DR   P65247, KTHY_SALTI ;  P65246, KTHY_SALTY ;  P36590, KTHY_SCHPO ;
DR   A8GD24, KTHY_SERP5 ;  A1S792, KTHY_SHEAM ;  Q081H9, KTHY_SHEFN ;
DR   A3QD98, KTHY_SHELP ;  Q8EDX8, KTHY_SHEON ;  A0KW30, KTHY_SHESA ;
DR   Q0HJN0, KTHY_SHESM ;  Q0HVX6, KTHY_SHESR ;  B2U523, KTHY_SHIB3 ;
DR   Q31ZF3, KTHY_SHIBS ;  Q32EV8, KTHY_SHIDS ;  Q0T5T8, KTHY_SHIF8 ;
DR   P0A721, KTHY_SHIFL ;  Q3Z319, KTHY_SHISS ;  Q5LPV9, KTHY_SILPO ;
DR   Q2NU35, KTHY_SODGM ;  A5V3I6, KTHY_SPHWW ;  A7WYM2, KTHY_STAA1 ;
DR   A6TYV6, KTHY_STAA2 ;  Q2FJG0, KTHY_STAA3 ;  Q2G230, KTHY_STAA8 ;
DR   A5IQ34, KTHY_STAA9 ;  Q2YVW3, KTHY_STAAB ;  Q5HIJ5, KTHY_STAAC ;
DR   P65248, KTHY_STAAM ;  P65249, KTHY_STAAN ;  Q6GJI9, KTHY_STAAR ;
DR   Q6GC06, KTHY_STAAS ;  Q8NY05, KTHY_STAAW ;  Q5HRS3, KTHY_STAEQ ;
DR   Q8CQT7, KTHY_STAES ;  Q4L3D9, KTHY_STAHJ ;  A3DM71, KTHY_STAMF ;
DR   Q49UZ1, KTHY_STAS1 ;  Q3JZV8, KTHY_STRA1 ;  Q8E3X8, KTHY_STRA3 ;
DR   Q8DYB3, KTHY_STRA5 ;  C0M7M5, KTHY_STRE4 ;  A8AYF8, KTHY_STRGC ;
DR   Q8DSU6, KTHY_STRMU ;  Q9A190, KTHY_STRP1 ;  Q04KZ0, KTHY_STRP2 ;
DR   P0DC02, KTHY_STRP3 ;  B5E437, KTHY_STRP4 ;  Q5XDM2, KTHY_STRP6 ;
DR   C1C6R6, KTHY_STRP7 ;  Q8P2B1, KTHY_STRP8 ;  A2RG70, KTHY_STRPG ;
DR   B1IBA2, KTHY_STRPI ;  B8ZP37, KTHY_STRPJ ;  Q97R91, KTHY_STRPN ;
DR   P0DC03, KTHY_STRPQ ;  B2IP90, KTHY_STRPS ;  B5XK00, KTHY_STRPZ ;
DR   Q8DQ58, KTHY_STRR6 ;  C0MGT8, KTHY_STRS7 ;  A3CPJ9, KTHY_STRSV ;
DR   Q5M0Z9, KTHY_STRT1 ;  Q5M5I6, KTHY_STRT2 ;  Q03LW8, KTHY_STRTD ;
DR   B9DTV7, KTHY_STRU0 ;  C1CDT1, KTHY_STRZJ ;  C1CK20, KTHY_STRZP ;
DR   C1CRV9, KTHY_STRZT ;  Q4JAC4, KTHY_SULAC ;  Q30RH7, KTHY_SULDN ;
DR   A6Q9Z8, KTHY_SULNB ;  B2V7X0, KTHY_SULSY ;  Q67JB0, KTHY_SYMTH ;
DR   Q2LUB1, KTHY_SYNAS ;  Q2JR37, KTHY_SYNJA ;  Q2JN62, KTHY_SYNJB ;
DR   A5GP05, KTHY_SYNPW ;  Q7U437, KTHY_SYNPX ;  A5GQJ8, KTHY_SYNR3 ;
DR   Q0I6Z1, KTHY_SYNS3 ;  Q3B043, KTHY_SYNS9 ;  Q3AH20, KTHY_SYNSC ;
DR   Q55593, KTHY_SYNY3 ;  C5BU64, KTHY_TERTT ;  B7IHT2, KTHY_THEAB ;
DR   Q9HLZ2, KTHY_THEAC ;  Q8DHA4, KTHY_THEEB ;  C5A1K2, KTHY_THEGJ ;
DR   A6LLI7, KTHY_THEM4 ;  Q9X0I3, KTHY_THEMA ;  B6YSZ4, KTHY_THEON ;
DR   A5IN77, KTHY_THEP1 ;  B0K7K7, KTHY_THEP3 ;  B0K119, KTHY_THEPX ;
DR   B9KXL4, KTHY_THERP ;  C6A0S1, KTHY_THESM ;  B1L821, KTHY_THESQ ;
DR   Q72I89, KTHY_THET2 ;  Q5SHX3, KTHY_THET8 ;  Q8RDE6, KTHY_THETN ;
DR   Q97CC8, KTHY_THEVO ;  Q3SIM9, KTHY_THIDA ;  O83373, KTHY_TREPA ;
DR   Q115I0, KTHY_TRIEI ;  Q83HB8, KTHY_TROW8 ;  Q83FM3, KTHY_TROWT ;
DR   B1AI06, KTHY_UREP2 ;  Q9PRC5, KTHY_UREPA ;  Q76RA8, KTHY_VACCA ;
DR   P68693, KTHY_VACCC ;  Q77TG7, KTHY_VACCT ;  Q80HT9, KTHY_VACCW ;
DR   P33803, KTHY_VAR67 ;  A1WGM5, KTHY_VEREI ;  A5CXH6, KTHY_VESOH ;
DR   A5F6P9, KTHY_VIBC3 ;  Q9KQI2, KTHY_VIBCH ;  C3LNW7, KTHY_VIBCM ;
DR   Q5E416, KTHY_VIBF1 ;  B5FG34, KTHY_VIBFM ;  A7MVG2, KTHY_VIBHB ;
DR   Q87N26, KTHY_VIBPA ;  Q8D8H5, KTHY_VIBVU ;  Q7MLZ6, KTHY_VIBVY ;
DR   Q8D3A7, KTHY_WIGBR ;  Q73FS2, KTHY_WOLPM ;  B3CM94, KTHY_WOLPP ;
DR   Q7M9X1, KTHY_WOLSU ;  Q5GTD5, KTHY_WOLTR ;  Q8PFG7, KTHY_XANAC ;
DR   Q3BN25, KTHY_XANC5 ;  Q4UPG4, KTHY_XANC8 ;  B0RXV1, KTHY_XANCB ;
DR   Q8P3Y6, KTHY_XANCP ;  Q2P8H9, KTHY_XANOM ;  B2SS96, KTHY_XANOP ;
DR   Q5H5T5, KTHY_XANOR ;  B2I7G4, KTHY_XYLF2 ;  Q9PFS7, KTHY_XYLFA ;
DR   B0U447, KTHY_XYLFM ;  Q87B89, KTHY_XYLFT ;  P00572, KTHY_YEAST ;
DR   A1JN89, KTHY_YERE8 ;  A7FH32, KTHY_YERP3 ;  Q1C6N6, KTHY_YERPA ;
DR   B2K751, KTHY_YERPB ;  O69169, KTHY_YERPE ;  A9R3P0, KTHY_YERPG ;
DR   Q1CI27, KTHY_YERPN ;  A4TLR5, KTHY_YERPP ;  Q669L8, KTHY_YERPS ;
DR   B1JI38, KTHY_YERPY ;
//
ID   2.7.4.10
DE   Nucleoside-triphosphate--adenylate kinase.
CA   NTP + AMP = NDP + ADP.
CC   -!- Many nucleoside triphosphates can act as donors.
PR   PROSITE; PDOC00104;
DR   P08760, KAD3_BOVIN ;  Q9UIJ7, KAD3_HUMAN ;  Q9WTP7, KAD3_MOUSE ;
DR   Q5RDZ0, KAD3_PONAB ;  P29411, KAD3_RAT   ;
//
ID   2.7.4.11
DE   (Deoxy)adenylate kinase.
CA   ATP + dAMP = ADP + dADP.
CC   -!- AMP can also act as acceptor.
//
ID   2.7.4.12
DE   T(2)-induced deoxynucleotide kinase.
CA   ATP + dGMP (or dTMP) = ADP + dGDP (or dTDP).
CC   -!- dTMP and dAMP can act as acceptors.
CC   -!- dATP can act as donor.
//
ID   2.7.4.13
DE   (Deoxy)nucleoside-phosphate kinase.
CA   ATP + deoxynucleoside phosphate = ADP + deoxynucleoside diphosphate.
CC   -!- dATP can substitute for ATP.
DR   Q7Y4Y9, DNMK_BPR69 ;  P04531, DNMK_BPT4  ;  Q5UQ70, DNMK_MIMIV ;
//
ID   2.7.4.14
DE   UMP/CMP kinase.
AN   CMP kinase.
AN   Cytidine monophosphate kinase.
AN   Cytidylate kinase.
AN   dCMP kinase.
AN   Deoxycytidine kinase.
AN   Deoxycytidylate kinase.
AN   UMP-CMP kinase.
AN   Uridine monophosphate-cytidine monophosphate phosphotransferase.
CA   (1) ATP + (d)CMP = ADP + (d)CDP.
CA   (2) ATP + UMP = ADP + UDP.
CC   -!- This eukaryotic enzyme is a bifunctional enzyme that catalyzes the
CC       phosphorylation of both CMP and UMP with similar efficiency.
CC   -!- dCMP can also act as acceptor.
CC   -!- Different from the monofunctional prokaryotic enzymes EC 2.7.4.25,
CC       CMP kinase and EC 2.7.4.22, UMP kinase.
CC   -!- This eukaryotic enzyme is a bifunctional enzyme that catalyzes the
CC       phosphorylation of both CMP and UMP with similar efficiency.
CC   -!- dCMP can also act as acceptor.
CC   -!- Different from the monofunctional prokaryotic enzymes EC 2.7.4.25 and
CC       EC 2.7.4.22.
CC   -!- Formerly EC 2.7.4.5.
PR   PROSITE; PDOC00104;
DR   Q5EBM0, CMPK2_HUMAN;  Q3U5Q7, CMPK2_MOUSE;  Q0SP35, KCY1_BORAP ;
DR   O51154, KCY1_BORBU ;  Q662N3, KCY1_BORGA ;  P43892, KCY1_HAEIN ;
DR   Q0SM32, KCY2_BORAP ;  O51759, KCY2_BORBU ;  Q65ZV5, KCY2_BORGA ;
DR   P43893, KCY2_HAEIN ;  A9NGK9, KCY_ACHLI  ;  Q6F9Y6, KCY_ACIAD  ;
DR   B7H3L0, KCY_ACIB3  ;  B7I530, KCY_ACIB5  ;  B2HZE4, KCY_ACIBC  ;
DR   B0VN00, KCY_ACIBS  ;  A3M504, KCY_ACIBT  ;  B0VD21, KCY_ACIBY  ;
DR   A5FUH7, KCY_ACICJ  ;  A6VPL0, KCY_ACTSZ  ;  A0KJ92, KCY_AERHH  ;
DR   Q9YDD5, KCY_AERPE  ;  A4SLS4, KCY_AERS4  ;  Q8U8I9, KCY_AGRT5  ;
DR   B6EIX9, KCY_ALISL  ;  A6TRG1, KCY_ALKMQ  ;  A8MFE4, KCY_ALKOO  ;
DR   B9MRX1, KCY_ANATD  ;  B7GHN1, KCY_ANOFW  ;  O67907, KCY_AQUAE  ;
DR   O28379, KCY_ARCFU  ;  Q2NIZ4, KCY_AYWBP  ;  A8IKN6, KCY_AZOC5  ;
DR   C1DRR3, KCY_AZOVD  ;  A7Z640, KCY_BACA2  ;  C3P584, KCY_BACAA  ;
DR   C3L9G1, KCY_BACAC  ;  A0RBV2, KCY_BACAH  ;  Q81SX6, KCY_BACAN  ;
DR   B7JGY2, KCY_BACC0  ;  O05386, KCY_BACC1  ;  B7IP75, KCY_BACC2  ;
DR   C1EMZ4, KCY_BACC3  ;  B7HHQ0, KCY_BACC4  ;  B7HL06, KCY_BACC7  ;
DR   A7GN34, KCY_BACCN  ;  B9IVL9, KCY_BACCQ  ;  Q81FS2, KCY_BACCR  ;
DR   Q63DN5, KCY_BACCZ  ;  Q5L9K4, KCY_BACFN  ;  Q64PU2, KCY_BACFR  ;
DR   Q9RC80, KCY_BACHD  ;  Q6HL58, KCY_BACHK  ;  Q65I08, KCY_BACLD  ;
DR   A8FEM5, KCY_BACP2  ;  Q5WGU8, KCY_BACSK  ;  P38493, KCY_BACSU  ;
DR   Q8A626, KCY_BACTN  ;  A6L1P6, KCY_BACV8  ;  A9VMA5, KCY_BACWK  ;
DR   A1UU99, KCY_BARBK  ;  Q6G546, KCY_BARHE  ;  Q6G0X4, KCY_BARQU  ;
DR   A9ILM1, KCY_BART1  ;  Q6MP09, KCY_BDEBA  ;  B2IKW6, KCY_BEII9  ;
DR   Q7VR42, KCY_BLOFL  ;  Q9RND6, KCY_BORBR  ;  B7J161, KCY_BORBZ  ;
DR   B5RLK3, KCY_BORDL  ;  B2RZJ4, KCY_BORHD  ;  Q7W603, KCY_BORPA  ;
DR   Q7VZG1, KCY_BORPE  ;  B5RQV4, KCY_BORRA  ;  A1QYS8, KCY_BORT9  ;
DR   Q2KIW9, KCY_BOVIN  ;  Q89WF1, KCY_BRAJA  ;  A4YJJ2, KCY_BRASO  ;
DR   B2S7T1, KCY_BRUA1  ;  Q2YPN5, KCY_BRUA2  ;  Q57FY7, KCY_BRUAB  ;
DR   A9M6N1, KCY_BRUC2  ;  C0RG91, KCY_BRUMB  ;  Q8YEG2, KCY_BRUME  ;
DR   A5VMX5, KCY_BRUO2  ;  B0CI46, KCY_BRUSI  ;  Q8G3C3, KCY_BRUSU  ;
DR   P59580, KCY_BUCBP  ;  B1YV34, KCY_BURA4  ;  Q1BY27, KCY_BURCA  ;
DR   B1JXS0, KCY_BURCC  ;  A0K5M2, KCY_BURCH  ;  B4EB41, KCY_BURCJ  ;
DR   Q0BH92, KCY_BURCM  ;  A9ADV5, KCY_BURM1  ;  A3MHN9, KCY_BURM7  ;
DR   A2S4R9, KCY_BURM9  ;  Q62M26, KCY_BURMA  ;  A1V6M2, KCY_BURMS  ;
DR   A3NXX0, KCY_BURP0  ;  A3NC31, KCY_BURP6  ;  B2JF05, KCY_BURP8  ;
DR   B2T629, KCY_BURPP  ;  Q63S05, KCY_BURPS  ;  Q39IG0, KCY_BURS3  ;
DR   Q2SY25, KCY_BURTA  ;  A4JCH5, KCY_BURVG  ;  Q13VC3, KCY_BURXL  ;
DR   A4XKN9, KCY_CALS8  ;  Q3AAT8, KCY_CARHZ  ;  B8H6A7, KCY_CAUCN  ;
DR   Q9A2H3, KCY_CAUCR  ;  B0T271, KCY_CAUSK  ;  Q5ZKE7, KCY_CHICK  ;
DR   Q5L6U2, KCY_CHLAB  ;  B8GA54, KCY_CHLAD  ;  Q824H2, KCY_CHLCV  ;
DR   Q253D3, KCY_CHLFF  ;  Q9PJU0, KCY_CHLMU  ;  Q9Z7Y5, KCY_CHLPN  ;
DR   B0B825, KCY_CHLT2  ;  B3QSU1, KCY_CHLT3  ;  Q3KLP6, KCY_CHLTA  ;
DR   B0BC90, KCY_CHLTB  ;  Q8KFN6, KCY_CHLTE  ;  O84458, KCY_CHLTR  ;
DR   Q7NTK7, KCY_CHRVO  ;  A8AIH4, KCY_CITK8  ;  Q97I08, KCY_CLOAB  ;
DR   A7FUL8, KCY_CLOB1  ;  A5I2T0, KCY_CLOBH  ;  C1FNU7, KCY_CLOBJ  ;
DR   B1IM76, KCY_CLOBK  ;  A7GE53, KCY_CLOBL  ;  B1KSB1, KCY_CLOBM  ;
DR   Q187C4, KCY_CLOD6  ;  Q0TRF4, KCY_CLOP1  ;  Q8XLF7, KCY_CLOPE  ;
DR   Q0STT4, KCY_CLOPS  ;  Q895G1, KCY_CLOTE  ;  Q482G4, KCY_COLP3  ;
DR   Q6NHE2, KCY_CORDI  ;  Q8FTK6, KCY_COREF  ;  Q8NQK7, KCY_CORGL  ;
DR   Q83E10, KCY_COXBU  ;  Q0KDH7, KCY_CUPNH  ;  Q46Y52, KCY_CUPPJ  ;
DR   B3R370, KCY_CUPTR  ;  Q11YY6, KCY_CYTH3  ;  Q7ZWE9, KCY_DANRE  ;
DR   C1CZK3, KCY_DEIDV  ;  Q1IW70, KCY_DEIGD  ;  Q9RRE9, KCY_DEIRA  ;
DR   C6BVN3, KCY_DESAD  ;  Q311Z5, KCY_DESDG  ;  B8G2Q5, KCY_DESHD  ;
DR   Q24V96, KCY_DESHY  ;  B8D5U4, KCY_DESK1  ;  A4J3N3, KCY_DESRM  ;
DR   Q72DA1, KCY_DESVH  ;  A1VEW5, KCY_DESVV  ;  P20425, KCY_DICDI  ;
DR   A5EWQ0, KCY_DICNV  ;  A8LSF1, KCY_DINSH  ;  A7ZJZ9, KCY_ECO24  ;
DR   B7UMZ6, KCY_ECO27  ;  B7MHL9, KCY_ECO45  ;  B7LDA2, KCY_ECO55  ;
DR   P0A6I2, KCY_ECO57  ;  B5YT44, KCY_ECO5E  ;  B7NM64, KCY_ECO7I  ;
DR   B7MS25, KCY_ECO81  ;  B7M839, KCY_ECO8A  ;  C4ZQ36, KCY_ECOBW  ;
DR   B1X850, KCY_ECODH  ;  A7ZYL3, KCY_ECOHS  ;  A1A9I7, KCY_ECOK1  ;
DR   Q0TJE3, KCY_ECOL5  ;  P0A6I1, KCY_ECOL6  ;  B1IW21, KCY_ECOLC  ;
DR   P0A6I0, KCY_ECOLI  ;  B7NAQ9, KCY_ECOLU  ;  B6I8Y2, KCY_ECOSE  ;
DR   B1LJV3, KCY_ECOSM  ;  Q1RDU8, KCY_ECOUT  ;  C5BBS1, KCY_EDWI9  ;
DR   Q8SS83, KCY_ENCCU  ;  A4W8S9, KCY_ENT38  ;  B7XIW9, KCY_ENTBH  ;
DR   Q834T6, KCY_ENTFA  ;  Q6D402, KCY_ERWCT  ;  B2VC78, KCY_ERWT9  ;
DR   B7LN72, KCY_ESCF3  ;  B1YI33, KCY_EXIS2  ;  C4L6M0, KCY_EXISA  ;
DR   A7HME6, KCY_FERNB  ;  A5FG91, KCY_FLAJ1  ;  A6H0A6, KCY_FLAPJ  ;
DR   Q8RII8, KCY_FUSNN  ;  B5E9T0, KCY_GEOBB  ;  Q5KXS4, KCY_GEOKA  ;
DR   Q749Y7, KCY_GEOSL  ;  C6E2B2, KCY_GEOSM  ;  C5D3G6, KCY_GEOSW  ;
DR   A4IQA8, KCY_GEOTN  ;  Q0BQI0, KCY_GRABC  ;  Q7VLS0, KCY_HAEDU  ;
DR   B9LPV4, KCY_HALLT  ;  Q5UXH0, KCY_HALMA  ;  B0R685, KCY_HALS3  ;
DR   Q9HPA5, KCY_HALSA  ;  Q18GM4, KCY_HALWD  ;  A9B5Y6, KCY_HERA2  ;
DR   P30085, KCY_HUMAN  ;  B4U600, KCY_HYDS0  ;  A8AAI6, KCY_IGNH4  ;
DR   B5XY86, KCY_KLEP3  ;  A6T702, KCY_KLEP7  ;  B2GC33, KCY_LACF3  ;
DR   Q043U2, KCY_LACGA  ;  Q74JL8, KCY_LACJO  ;  Q9CEY1, KCY_LACLA  ;
DR   A2RJ85, KCY_LACLM  ;  Q02XH5, KCY_LACLS  ;  Q88VZ4, KCY_LACPL  ;
DR   A5VJK2, KCY_LACRD  ;  B2G716, KCY_LACRJ  ;  Q1WTS4, KCY_LACS1  ;
DR   Q1MPW3, KCY_LAWIP  ;  Q6AGF7, KCY_LEIXX  ;  Q04U41, KCY_LEPBJ  ;
DR   Q04ZI4, KCY_LEPBL  ;  Q8F6P4, KCY_LEPIN  ;  B1MYB3, KCY_LEUCK  ;
DR   Q03WN2, KCY_LEUMM  ;  Q92A69, KCY_LISIN  ;  C1KWN9, KCY_LISMC  ;
DR   Q71Y76, KCY_LISMF  ;  B8DBY7, KCY_LISMH  ;  Q8Y5W6, KCY_LISMO  ;
DR   A0AK51, KCY_LISW6  ;  B1HT93, KCY_LYSSC  ;  B9E6L7, KCY_MACCJ  ;
DR   Q2VZA9, KCY_MAGSA  ;  A0L407, KCY_MAGSM  ;  Q65SH6, KCY_MANSM  ;
DR   A6VZ89, KCY_MARMS  ;  Q6F1R8, KCY_MESFL  ;  A6UW32, KCY_META3  ;
DR   Q8TRR6, KCY_METAC  ;  A7I5R5, KCY_METB6  ;  Q46GC2, KCY_METBF  ;
DR   Q12ZS5, KCY_METBU  ;  Q608S6, KCY_METCA  ;  Q2FTU1, KCY_METHJ  ;
DR   Q58071, KCY_METJA  ;  Q8TZB3, KCY_METKA  ;  A2SPM8, KCY_METLZ  ;
DR   A4FYK1, KCY_METM5  ;  A9A698, KCY_METM6  ;  A6VJT1, KCY_METM7  ;
DR   Q8PV21, KCY_METMA  ;  A3CT23, KCY_METMJ  ;  Q6LZK1, KCY_METMP  ;
DR   B8GKF9, KCY_METPE  ;  A5UL61, KCY_METS3  ;  B0UC53, KCY_METS4  ;
DR   B8EN73, KCY_METSB  ;  Q2NFY4, KCY_METST  ;  O26138, KCY_METTH  ;
DR   A0B9U5, KCY_METTP  ;  A6USC1, KCY_METVS  ;  Q9DBP5, KCY_MOUSE  ;
DR   A0QH60, KCY_MYCA1  ;  A5IZG6, KCY_MYCAP  ;  P63804, KCY_MYCBO  ;
DR   A1KJC9, KCY_MYCBP  ;  C1ANY5, KCY_MYCBT  ;  Q2SRR6, KCY_MYCCT  ;
DR   Q7NBV1, KCY_MYCGA  ;  P47572, KCY_MYCGE  ;  Q601X7, KCY_MYCH2  ;
DR   Q4A8U3, KCY_MYCH7  ;  Q4AAR2, KCY_MYCHJ  ;  B8ZRI2, KCY_MYCLB  ;
DR   Q49885, KCY_MYCLE  ;  Q6MTJ7, KCY_MYCMS  ;  Q740D7, KCY_MYCPA  ;
DR   P75308, KCY_MYCPN  ;  Q98RC0, KCY_MYCPU  ;  Q4A6Q8, KCY_MYCS5  ;
DR   A5U371, KCY_MYCTA  ;  P63803, KCY_MYCTU  ;  Q3IMV8, KCY_NATPD  ;
DR   Q5F904, KCY_NEIG1  ;  P57064, KCY_NEIMA  ;  P57065, KCY_NEIMB  ;
DR   A1KUC8, KCY_NEIMF  ;  Q0AIZ4, KCY_NITEC  ;  Q82TD5, KCY_NITEU  ;
DR   Q1QRT2, KCY_NITHX  ;  Q3JEN4, KCY_NITOC  ;  Q3SW65, KCY_NITWN  ;
DR   Q5YY83, KCY_NOCFA  ;  C4V9G9, KCY_NOSCE  ;  Q8CXF5, KCY_OCEIH  ;
DR   B6JCN5, KCY_OLICO  ;  Q6YQY4, KCY_ONYPE  ;  A6LIB2, KCY_PARD8  ;
DR   Q6MEF6, KCY_PARUW  ;  P57875, KCY_PASMU  ;  C6DF66, KCY_PECCP  ;
DR   Q03F87, KCY_PEDPA  ;  Q3A3D2, KCY_PELCD  ;  B4SCU3, KCY_PELPB  ;
DR   A5D1V4, KCY_PELTS  ;  Q7N6D4, KCY_PHOLL  ;  Q6LPE2, KCY_PHOPR  ;
DR   B1VAZ2, KCY_PHYAS  ;  B3R0E5, KCY_PHYMT  ;  Q29561, KCY_PIG    ;
DR   B1XVQ2, KCY_POLNS  ;  A4SW55, KCY_POLSQ  ;  B2RIH0, KCY_PORG3  ;
DR   Q7MWK7, KCY_PORGI  ;  Q6A8F7, KCY_PROAC  ;  B4ET26, KCY_PROMH  ;
DR   Q48FN1, KCY_PSE14  ;  A6V2R2, KCY_PSEA7  ;  B7VAL6, KCY_PSEA8  ;
DR   Q02PW9, KCY_PSEAB  ;  Q9HZ70, KCY_PSEAE  ;  Q1ID99, KCY_PSEE4  ;
DR   Q4K8N2, KCY_PSEF5  ;  C3K6J9, KCY_PSEFS  ;  Q3K8U4, KCY_PSEPF  ;
DR   B0KTY0, KCY_PSEPG  ;  Q88M04, KCY_PSEPK  ;  B1J5H0, KCY_PSEPW  ;
DR   Q885T2, KCY_PSESM  ;  Q4ZQ97, KCY_PSEU2  ;  A4VLZ2, KCY_PSEU5  ;
DR   Q9UZJ6, KCY_PYRAB  ;  Q8ZTJ1, KCY_PYRAE  ;  A4WKL0, KCY_PYRAR  ;
DR   A3MV67, KCY_PYRCJ  ;  Q8U2L4, KCY_PYRFU  ;  O58988, KCY_PYRHO  ;
DR   A1RRJ5, KCY_PYRIL  ;  Q5JJE3, KCY_PYRKO  ;  Q1LQG9, KCY_RALME  ;
DR   B2U887, KCY_RALPJ  ;  Q8Y0Y5, KCY_RALSO  ;  Q4KM73, KCY_RAT    ;
DR   Q98CC2, KCY_RHILO  ;  Q92SV4, KCY_RHIME  ;  Q7UEW6, KCY_RHOBA  ;
DR   C1ASX3, KCY_RHOOB  ;  Q2J2F8, KCY_RHOP2  ;  Q07UH9, KCY_RHOP5  ;
DR   Q6NDP2, KCY_RHOPA  ;  Q21CB3, KCY_RHOPB  ;  Q13EQ8, KCY_RHOPS  ;
DR   B3Q5Z9, KCY_RHOPT  ;  Q2RXP6, KCY_RHORT  ;  Q9X4E0, KCY_RHOS4  ;
DR   B9KU94, KCY_RHOSK  ;  Q0SI81, KCY_RHOSR  ;  C3PNP6, KCY_RICAE  ;
DR   A8GNZ6, KCY_RICAH  ;  A8GX62, KCY_RICB8  ;  Q1RJH0, KCY_RICBR  ;
DR   A8EYM7, KCY_RICCK  ;  Q92HM3, KCY_RICCN  ;  Q4ULF2, KCY_RICFE  ;
DR   Q9ZD27, KCY_RICPR  ;  C4K1D2, KCY_RICPU  ;  B0BXZ0, KCY_RICRO  ;
DR   A8GSH6, KCY_RICRS  ;  Q68WL3, KCY_RICTY  ;  A7NHN1, KCY_ROSCS  ;
DR   Q21IS9, KCY_SACD2  ;  B5F163, KCY_SALA4  ;  A9MHX2, KCY_SALAR  ;
DR   Q57R21, KCY_SALCH  ;  B5FQ53, KCY_SALDC  ;  B5QZB4, KCY_SALEP  ;
DR   B5R8J7, KCY_SALG2  ;  B4TD40, KCY_SALHS  ;  B4T144, KCY_SALNS  ;
DR   Q5PGG7, KCY_SALPA  ;  A9N7V4, KCY_SALPB  ;  C0PXU6, KCY_SALPC  ;
DR   B5BBP7, KCY_SALPK  ;  Q2S1M6, KCY_SALRD  ;  B4TRU1, KCY_SALSV  ;
DR   Q8Z803, KCY_SALTI  ;  Q8ZQC4, KCY_SALTY  ;  A8GCH2, KCY_SERP5  ;
DR   A1S6D4, KCY_SHEAM  ;  B8EA96, KCY_SHEB2  ;  A3D4A7, KCY_SHEB5  ;
DR   A6WNM9, KCY_SHEB8  ;  A9L2X6, KCY_SHEB9  ;  Q12NE0, KCY_SHEDO  ;
DR   Q081U5, KCY_SHEFN  ;  B0TT44, KCY_SHEHH  ;  A3QEC1, KCY_SHELP  ;
DR   Q8EEH9, KCY_SHEON  ;  A8H4A5, KCY_SHEPA  ;  A4Y731, KCY_SHEPC  ;
DR   B8CMH3, KCY_SHEPW  ;  A0KWN8, KCY_SHESA  ;  A8FVN5, KCY_SHESH  ;
DR   Q0HIX0, KCY_SHESM  ;  Q0HV12, KCY_SHESR  ;  A1RJF9, KCY_SHESW  ;
DR   B1KF48, KCY_SHEWM  ;  B2TUH1, KCY_SHIB3  ;  Q31YU0, KCY_SHIBS  ;
DR   Q32E30, KCY_SHIDS  ;  Q0SX05, KCY_SHIF8  ;  Q83LP1, KCY_SHIFL  ;
DR   Q3Z3L1, KCY_SHISS  ;  A6UF45, KCY_SINMW  ;  Q2NUA8, KCY_SODGM  ;
DR   Q02CZ9, KCY_SOLUE  ;  A7X2I6, KCY_STAA1  ;  A6U1U6, KCY_STAA2  ;
DR   A5IT05, KCY_STAA9  ;  Q2YY79, KCY_STAAB  ;  Q5HFU6, KCY_STAAC  ;
DR   A6QH26, KCY_STAAE  ;  P63805, KCY_STAAM  ;  P63806, KCY_STAAN  ;
DR   Q6GGT4, KCY_STAAR  ;  Q6G986, KCY_STAAS  ;  A8Z457, KCY_STAAT  ;
DR   P63807, KCY_STAAW  ;  B9DNU7, KCY_STACT  ;  Q5HP68, KCY_STAEQ  ;
DR   Q8CSH5, KCY_STAES  ;  Q4L6I2, KCY_STAHJ  ;  A3DND3, KCY_STAMF  ;
DR   Q49XT1, KCY_STAS1  ;  Q3K0C7, KCY_STRA1  ;  Q8E4E6, KCY_STRA3  ;
DR   Q8DYT8, KCY_STRA5  ;  Q828Y9, KCY_STRAW  ;  Q9EWW6, KCY_STRCO  ;
DR   C0M8S8, KCY_STRE4  ;  B4U2J8, KCY_STREM  ;  A8AX10, KCY_STRGC  ;
DR   B1W221, KCY_STRGG  ;  B4SSV1, KCY_STRM5  ;  B2FNP4, KCY_STRMK  ;
DR   Q8DV23, KCY_STRMU  ;  Q9A0F0, KCY_STRP1  ;  Q04JF3, KCY_STRP2  ;
DR   P0DA38, KCY_STRP3  ;  B5E6P3, KCY_STRP4  ;  Q5XCU3, KCY_STRP6  ;
DR   C1C8J2, KCY_STRP7  ;  Q8P1H8, KCY_STRP8  ;  Q1JCH3, KCY_STRPB  ;
DR   Q1JMF1, KCY_STRPC  ;  Q1JHJ8, KCY_STRPD  ;  Q1J7B9, KCY_STRPF  ;
DR   A2RF85, KCY_STRPG  ;  B1ID16, KCY_STRPI  ;  B8ZM16, KCY_STRPJ  ;
DR   Q48U95, KCY_STRPM  ;  Q97PK6, KCY_STRPN  ;  P0DA39, KCY_STRPQ  ;
DR   B2IRB6, KCY_STRPS  ;  B5XKT7, KCY_STRPZ  ;  Q8DNY9, KCY_STRR6  ;
DR   A4W254, KCY_STRS2  ;  A3CNZ0, KCY_STRSV  ;  A4VVU8, KCY_STRSY  ;
DR   Q5LZL6, KCY_STRT1  ;  Q5M469, KCY_STRT2  ;  Q03KI8, KCY_STRTD  ;
DR   B9DU39, KCY_STRU0  ;  C1CFI5, KCY_STRZJ  ;  C1CLU8, KCY_STRZP  ;
DR   C1CSM2, KCY_STRZT  ;  O05982, KCY_SULAC  ;  C3N5V4, KCY_SULIA  ;
DR   C4KHI3, KCY_SULIK  ;  C3MQ86, KCY_SULIL  ;  C3MVX8, KCY_SULIM  ;
DR   C3NH82, KCY_SULIN  ;  C3NEH0, KCY_SULIY  ;  Q9UX81, KCY_SULSO  ;
DR   Q975K7, KCY_SULTO  ;  Q67NU0, KCY_SYMTH  ;  A0LK48, KCY_SYNFM  ;
DR   B7IE32, KCY_THEAB  ;  Q9HIT3, KCY_THEAC  ;  A8F7R9, KCY_THELT  ;
DR   A6LNG5, KCY_THEM4  ;  Q9X1F6, KCY_THEMA  ;  B9K8E3, KCY_THENN  ;
DR   B1YAJ8, KCY_THENV  ;  A5IME2, KCY_THEP1  ;  C6A187, KCY_THESM  ;
DR   B1LBI1, KCY_THESQ  ;  Q72LH0, KCY_THET2  ;  Q5SL35, KCY_THET8  ;
DR   Q8RA78, KCY_THETN  ;  Q97BV0, KCY_THEVO  ;  B5YH69, KCY_THEYD  ;
DR   O83362, KCY_TREPA  ;  Q0W1W1, KCY_UNCMA  ;  B1AIY1, KCY_UREP2  ;
DR   Q9PQE9, KCY_UREPA  ;  B5ZBF2, KCY_UREU1  ;  Q9KQT2, KCY_VIBCH  ;
DR   Q5E3Z1, KCY_VIBF1  ;  B5FG59, KCY_VIBFM  ;  A7MUP2, KCY_VIBHB  ;
DR   Q87N44, KCY_VIBPA  ;  B7VH34, KCY_VIBSL  ;  Q8D8J1, KCY_VIBVU  ;
DR   Q7MLX7, KCY_VIBVY  ;  Q8PK76, KCY_XANAC  ;  Q3BSN5, KCY_XANC5  ;
DR   Q4UVD7, KCY_XANC8  ;  B0RSA3, KCY_XANCB  ;  Q8P8P4, KCY_XANCP  ;
DR   Q2P3S3, KCY_XANOM  ;  B2SLH6, KCY_XANOP  ;  Q5H0T8, KCY_XANOR  ;
DR   A7IEB7, KCY_XANP2  ;  Q7ZX23, KCY_XENLA  ;  Q28H12, KCY_XENTR  ;
DR   B2I6X2, KCY_XYLF2  ;  Q9PAQ6, KCY_XYLFA  ;  B0U3S8, KCY_XYLFM  ;
DR   Q87BJ6, KCY_XYLFT  ;  A1JMI5, KCY_YERE8  ;  A7FJW8, KCY_YERP3  ;
DR   Q1CA72, KCY_YERPA  ;  B2KA24, KCY_YERPB  ;  Q8ZGB3, KCY_YERPE  ;
DR   A9R7I3, KCY_YERPG  ;  Q1CGG6, KCY_YERPN  ;  A4TN17, KCY_YERPP  ;
DR   Q66CI7, KCY_YERPS  ;  B1JRD8, KCY_YERPY  ;  B0C6S1, PANCY_ACAM1;
DR   Q3MEJ8, PANCY_ANAVT;  Q7NJM6, PANCY_GLOVI;  Q8YSZ3, PANCY_NOSS1;
DR   A3PF80, PANCY_PROM0;  A2C536, PANCY_PROM1;  A8G795, PANCY_PROM2;
DR   A2CBX2, PANCY_PROM3;  Q318F2, PANCY_PROM9;  Q7V9S8, PANCY_PROMA;
DR   Q7V583, PANCY_PROMM;  Q7UZR6, PANCY_PROMP;  A2BTH1, PANCY_PROMS;
DR   Q46IM3, PANCY_PROMT;  Q31P38, PANCY_SYNE7;  Q2JRH9, PANCY_SYNJA;
DR   Q2JJ30, PANCY_SYNJB;  Q5N530, PANCY_SYNP6;  A5GIY5, PANCY_SYNPW;
DR   Q7U4P0, PANCY_SYNPX;  A5GVR3, PANCY_SYNR3;  Q0ICW2, PANCY_SYNS3;
DR   Q3AUV1, PANCY_SYNS9;  Q3AMJ0, PANCY_SYNSC;  Q55074, PANCY_SYNY3;
DR   Q8DG73, PANCY_THEEB;  Q110U9, PANCY_TRIEI;
//
ID   2.7.4.15
DE   Thiamine-diphosphate kinase.
CA   ATP + thiamine diphosphate = ADP + thiamine triphosphate.
//
ID   2.7.4.16
DE   Thiamine-phosphate kinase.
AN   Thiamine-monophosphate kinase.
CA   ATP + thiamine phosphate = ADP + thiamine diphosphate.
DR   O29525, THIL_ARCFU ;  O05514, THIL_BACSU ;  P57532, THIL_BUCAI ;
DR   Q8K9A5, THIL_BUCAP ;  Q8XE87, THIL_ECO57 ;  P0AGG1, THIL_ECOL6 ;
DR   P0AGG0, THIL_ECOLI ;  Q57190, THIL_HAEIN ;  Q60337, THIL_METJA ;
DR   O27447, THIL_METTH ;  Q9V1N8, THIL_PYRAB ;  O59497, THIL_PYRHO ;
DR   P55881, THIL_SALTY ;  Q54757, THIL_SYNE7 ;
//
ID   2.7.4.17
DE   3-phosphoglyceroyl-phosphate--polyphosphate phosphotransferase.
CA   3-phospho-D-glyceroyl phosphate + (phosphate)(n) = 3-phosphoglycerate +
CA   (phosphate)(n+1).
//
ID   2.7.4.18
DE   Farnesyl-diphosphate kinase.
CA   ATP + farnesyl diphosphate = ADP + farnesyl triphosphate.
CC   -!- ADP can also act as donor.
//
ID   2.7.4.19
DE   5-methyldeoxycytidine-5'-phosphate kinase.
CA   ATP + 5-methyldeoxycytidine 5'-phosphate = ADP + 5-methyldeoxycytidine
CA   diphosphate.
CC   -!- The enzyme, from phage XP-12-infected Xanthomonas oryzae, converts
CC       m(5)dCMP into m(5)dCDP and then into m(5)dCTP.
//
ID   2.7.4.20
DE   Dolichyl-diphosphate--polyphosphate phosphotransferase.
CA   Dolichyl diphosphate + (phosphate)(n) = dolichyl phosphate +
CA   (phosphate)(n+1).
//
ID   2.7.4.21
DE   Inositol-hexakisphosphate kinase.
AN   ATP:1D-myo-inositol-hexakisphosphate phosphotransferase.
CA   (1) ATP + 1D-myo-inositol hexakisphosphate = ADP + 5-diphospho-1D-myo-
CA   inositol (1,2,3,4,6)pentakisphosphate.
CA   (2) ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-
CA   1D-myo-inositol tetrakisphosphate (isomeric configuration unknown).
CC   -!- Three mammalian isoforms are known to exist.
CC   -!- Formerly EC 2.7.1.152.
DR   Q92551, IP6K1_HUMAN;  Q6PD10, IP6K1_MOUSE;  Q9ESM0, IP6K1_RAT  ;
DR   Q9UHH9, IP6K2_HUMAN;  Q80V72, IP6K2_MOUSE;  Q95221, IP6K2_RABIT;
DR   Q9R0U1, IP6K2_RAT  ;  Q96PC2, IP6K3_HUMAN;  Q8BWD2, IP6K3_MOUSE;
DR   Q12494, KCS1_YEAST ;  A7Z050, VIP1_BOVIN ;  P91309, VIP1_CAEEL ;
DR   Q9VR59, VIP1_DROME ;  Q6PFW1, VIP1_HUMAN ;  A2ARP1, VIP1_MOUSE ;
DR   Q5RDF1, VIP1_PONAB ;  P0C644, VIP1_RAT   ;  O74429, VIP1_SCHPO ;
DR   Q06685, VIP1_YEAST ;  O43314, VIP2_HUMAN ;  Q6ZQB6, VIP2_MOUSE ;
DR   Q5REW0, VIP2_PONAB ;  Q5XHF8, VIP2_XENLA ;
//
ID   2.7.4.22
DE   UMP kinase.
AN   UMP-kinase.
AN   UMPK.
AN   Uridine monophosphate kinase.
AN   Uridylate kinase.
CA   ATP + UMP = ADP + UDP.
CC   -!- Strictly specific for UMP as substrate and is used by prokaryotes in
CC       the de novo synthesis of pyrimidines, in contrast to eukaryotes,
CC       which use the dual-specificity enzyme EC 2.7.4.14 for the same
CC       purpose.
CC   -!- Subject of feedback regulation, being inhibited by UTP and activated
CC       by GTP.
DR   A1TN71, PYRH_ACIAC ;  Q6FCH3, PYRH_ACIAD ;  Q1IV36, PYRH_ACIBL ;
DR   A3M658, PYRH_ACIBT ;  A0LV52, PYRH_ACIC1 ;  A5G1L2, PYRH_ACICJ ;
DR   A1W916, PYRH_ACISJ ;  A3MZT5, PYRH_ACTP2 ;  A6VM31, PYRH_ACTSZ ;
DR   A0KHG5, PYRH_AERHH ;  Q9YF40, PYRH_AERPE ;  A4SQI0, PYRH_AERS4 ;
DR   Q8UFM1, PYRH_AGRT5 ;  Q0VQF5, PYRH_ALCBS ;  Q0A7I2, PYRH_ALHEH ;
DR   A6TRM1, PYRH_ALKMQ ;  A8MHH1, PYRH_ALKOO ;  Q2IMM2, PYRH_ANADE ;
DR   A7H724, PYRH_ANADF ;  Q5PBQ6, PYRH_ANAMM ;  Q2GLL2, PYRH_ANAPZ ;
DR   Q3MFI4, PYRH_ANAVT ;  O66929, PYRH_AQUAE ;  A8ESI8, PYRH_ARCB4 ;
DR   O28237, PYRH_ARCFU ;  Q5NZH3, PYRH_AROAE ;  A1R4W1, PYRH_ARTAT ;
DR   A0JUP3, PYRH_ARTS2 ;  Q2NIS4, PYRH_AYWBP ;  A8I467, PYRH_AZOC5 ;
DR   A1K6R9, PYRH_AZOSB ;  A7Z4S2, PYRH_BACA2 ;  Q81WL0, PYRH_BACAN ;
DR   Q819Y0, PYRH_BACCR ;  Q5LHK5, PYRH_BACFN ;  Q64YI2, PYRH_BACFR ;
DR   Q9KA65, PYRH_BACHD ;  Q65JJ7, PYRH_BACLD ;  Q5WFT0, PYRH_BACSK ;
DR   O31749, PYRH_BACSU ;  Q8A5J7, PYRH_BACTN ;  A6L1I4, PYRH_BACV8 ;
DR   Q8RT65, PYRH_BARBK ;  Q6G5C7, PYRH_BARHE ;  Q6FZN2, PYRH_BARQU ;
DR   Q1LSV5, PYRH_BAUCH ;  Q6MGY5, PYRH_BDEBA ;  A1A1I1, PYRH_BIFAA ;
DR   Q8G484, PYRH_BIFLO ;  Q7VRE4, PYRH_BLOFL ;  Q493D0, PYRH_BLOPB ;
DR   Q2L160, PYRH_BORA1 ;  Q7WJ92, PYRH_BORBR ;  Q7WA58, PYRH_BORPA ;
DR   Q7VYC8, PYRH_BORPE ;  Q89KP5, PYRH_BRAJA ;  A5EK53, PYRH_BRASB ;
DR   A4YVG4, PYRH_BRASO ;  Q57CX9, PYRH_BRUAB ;  Q8YHH4, PYRH_BRUME ;
DR   Q8G0D7, PYRH_BRUSU ;  P57327, PYRH_BUCAI ;  P59002, PYRH_BUCAP ;
DR   P59578, PYRH_BUCBP ;  Q057S9, PYRH_BUCCC ;  Q1BHI0, PYRH_BURCA ;
DR   A0K8E1, PYRH_BURCH ;  Q0BE17, PYRH_BURCM ;  A3MKU1, PYRH_BURM7 ;
DR   A2SB74, PYRH_BURM9 ;  Q62JC6, PYRH_BURMA ;  A1V567, PYRH_BURMS ;
DR   A3NWM9, PYRH_BURP0 ;  Q3JR30, PYRH_BURP1 ;  A3NAU6, PYRH_BURP6 ;
DR   Q63T14, PYRH_BURPS ;  Q39F45, PYRH_BURS3 ;  Q2SWZ6, PYRH_BURTA ;
DR   A4JF73, PYRH_BURVG ;  Q13XB8, PYRH_BURXL ;  A4XM00, PYRH_CALS8 ;
DR   A7ZEY4, PYRH_CAMC1 ;  A7GXE5, PYRH_CAMC5 ;  A0RQ89, PYRH_CAMFF ;
DR   A7I2U3, PYRH_CAMHC ;  A8FMY0, PYRH_CAMJ8 ;  A7H2A6, PYRH_CAMJD ;
DR   Q9PN24, PYRH_CAMJE ;  A1W0Q9, PYRH_CAMJJ ;  Q5HTI9, PYRH_CAMJR ;
DR   Q3AB79, PYRH_CARHZ ;  Q9A705, PYRH_CAUCR ;  A0RXT6, PYRH_CENSY ;
DR   Q5L765, PYRH_CHLAB ;  Q3AQ27, PYRH_CHLCH ;  Q824U5, PYRH_CHLCV ;
DR   Q252Q5, PYRH_CHLFF ;  P71147, PYRH_CHLMU ;  A1BHZ3, PYRH_CHLPD ;
DR   Q9Z7K7, PYRH_CHLPN ;  Q3KL16, PYRH_CHLTA ;  P59003, PYRH_CHLTE ;
DR   O84685, PYRH_CHLTR ;  Q1R031, PYRH_CHRSD ;  Q7NVZ2, PYRH_CHRVO ;
DR   A8ALB8, PYRH_CITK8 ;  A5CQS6, PYRH_CLAM3 ;  Q97I64, PYRH_CLOAB ;
DR   A7FPZ6, PYRH_CLOB1 ;  A5I4L0, PYRH_CLOBH ;  A7GG21, PYRH_CLOBL ;
DR   Q185S7, PYRH_CLOD6 ;  A0Q0R8, PYRH_CLONN ;  Q0TPQ5, PYRH_CLOP1 ;
DR   Q8XJQ8, PYRH_CLOPE ;  Q0SSC2, PYRH_CLOPS ;  Q895L0, PYRH_CLOTE ;
DR   A3DE57, PYRH_CLOTH ;  Q485G8, PYRH_COLP3 ;  Q6NGK6, PYRH_CORDI ;
DR   Q8FP74, PYRH_COREF ;  A4QF30, PYRH_CORGB ;  P59004, PYRH_CORGL ;
DR   Q4JV20, PYRH_CORJK ;  Q83BV3, PYRH_COXBU ;  Q0KA18, PYRH_CUPNH ;
DR   Q470D9, PYRH_CUPPJ ;  Q11XK2, PYRH_CYTH3 ;  Q47F90, PYRH_DECAR ;
DR   Q3Z9H8, PYRH_DEHE1 ;  Q3ZZC3, PYRH_DEHSC ;  Q1IZI8, PYRH_DEIGD ;
DR   Q9RU81, PYRH_DEIRA ;  Q313G6, PYRH_DESDG ;  Q24UF9, PYRH_DESHY ;
DR   Q6AP39, PYRH_DESPS ;  A4J5Z1, PYRH_DESRM ;  Q72DQ8, PYRH_DESVH ;
DR   A1VFB1, PYRH_DESVV ;  A5EV27, PYRH_DICNV ;  A7ZHR1, PYRH_ECO24 ;
DR   P0A7F1, PYRH_ECO57 ;  A7ZWB7, PYRH_ECOHS ;  A1A7L5, PYRH_ECOK1 ;
DR   Q0TLG2, PYRH_ECOL5 ;  P0A7F0, PYRH_ECOL6 ;  P0A7E9, PYRH_ECOLI ;
DR   Q1RG18, PYRH_ECOUT ;  Q3YR64, PYRH_EHRCJ ;  Q2GHJ6, PYRH_EHRCR ;
DR   Q5FG65, PYRH_EHRRG ;  Q5HAF8, PYRH_EHRRW ;  A4W6R6, PYRH_ENT38 ;
DR   Q831V1, PYRH_ENTFA ;  A7MGT0, PYRH_ENTS8 ;  Q6D8E1, PYRH_ERWCT ;
DR   Q2NBU2, PYRH_ERYLH ;  A7HL98, PYRH_FERNB ;  A6GWS3, PYRH_FLAPJ ;
DR   Q0RBL9, PYRH_FRAAA ;  Q2J528, PYRH_FRASC ;  Q14JD0, PYRH_FRAT1 ;
DR   A7N9R6, PYRH_FRATF ;  Q2A5I0, PYRH_FRATH ;  A0Q4H3, PYRH_FRATN ;
DR   Q0BNT7, PYRH_FRATO ;  Q5NHX8, PYRH_FRATT ;  A4IZU4, PYRH_FRATW ;
DR   Q8R6G5, PYRH_FUSNN ;  Q5L0K0, PYRH_GEOKA ;  Q39W86, PYRH_GEOMG ;
DR   Q74BW2, PYRH_GEOSL ;  A4IMC5, PYRH_GEOTN ;  Q7NI44, PYRH_GLOVI ;
DR   Q5FPZ5, PYRH_GLUOX ;  Q0BTM0, PYRH_GRABC ;  A0LXJ4, PYRH_GRAFK ;
DR   Q7VL82, PYRH_HAEDU ;  Q4QLM2, PYRH_HAEI8 ;  A5UD40, PYRH_HAEIE ;
DR   A5UIJ1, PYRH_HAEIG ;  P43890, PYRH_HAEIN ;  Q0I378, PYRH_HAES1 ;
DR   Q2SBP9, PYRH_HAHCH ;  A1WX19, PYRH_HALHL ;  B9LSL4, PYRH_HALLT ;
DR   Q5UXX3, PYRH_HALMA ;  B0R6V9, PYRH_HALS3 ;  Q9HNN8, PYRH_HALSA ;
DR   Q18DR1, PYRH_HALWD ;  Q17Y33, PYRH_HELAH ;  Q7VHX9, PYRH_HELHP ;
DR   Q1CT93, PYRH_HELPH ;  Q9ZL66, PYRH_HELPJ ;  P56106, PYRH_HELPY ;
DR   A4G4S3, PYRH_HERAR ;  A2BLM0, PYRH_HYPBU ;  Q0C1B9, PYRH_HYPNA ;
DR   Q5QXS2, PYRH_IDILO ;  A8AAG3, PYRH_IGNH4 ;  A6SZP9, PYRH_JANMA ;
DR   Q28PI5, PYRH_JANSC ;  A6T4X3, PYRH_KLEP7 ;  Q5FJM5, PYRH_LACAC ;
DR   Q03QS3, PYRH_LACBA ;  Q038L4, PYRH_LACC3 ;  Q1G9N8, PYRH_LACDA ;
DR   Q049U4, PYRH_LACDB ;  Q044C8, PYRH_LACGA ;  A8YVR7, PYRH_LACH4 ;
DR   Q74IR8, PYRH_LACJO ;  Q9CE38, PYRH_LACLA ;  Q9Z5K8, PYRH_LACLM ;
DR   Q02WC4, PYRH_LACLS ;  Q88VJ6, PYRH_LACPL ;  A5VJC7, PYRH_LACRD ;
DR   Q8VS53, PYRH_LACRE ;  Q1WUG5, PYRH_LACS1 ;  Q38W66, PYRH_LACSS ;
DR   Q1MRD8, PYRH_LAWIP ;  Q5X4J9, PYRH_LEGPA ;  A5ICK8, PYRH_LEGPC ;
DR   Q5ZUT0, PYRH_LEGPH ;  Q5WVY9, PYRH_LEGPL ;  Q6AEV5, PYRH_LEIXX ;
DR   Q04U70, PYRH_LEPBJ ;  Q053N3, PYRH_LEPBL ;  Q72U12, PYRH_LEPIC ;
DR   Q8F142, PYRH_LEPIN ;  Q03WX7, PYRH_LEUMM ;  P65928, PYRH_LISIN ;
DR   Q720A9, PYRH_LISMF ;  P65927, PYRH_LISMO ;  A0AIB4, PYRH_LISW6 ;
DR   Q2W4C5, PYRH_MAGSA ;  A0L8Q7, PYRH_MAGSM ;  Q65R73, PYRH_MANSM ;
DR   A1U3Q2, PYRH_MARAV ;  Q0APW3, PYRH_MARMM ;  Q6F0Q9, PYRH_MESFL ;
DR   Q11IJ6, PYRH_MESSB ;  A6UV05, PYRH_META3 ;  Q8TTQ4, PYRH_METAC ;
DR   A7I6B7, PYRH_METB6 ;  Q46EC7, PYRH_METBF ;  Q12VQ2, PYRH_METBU ;
DR   Q60BA8, PYRH_METCA ;  Q1H141, PYRH_METFK ;  Q2FR36, PYRH_METHJ ;
DR   Q58656, PYRH_METJA ;  Q8TXB4, PYRH_METKA ;  A2SS66, PYRH_METLZ ;
DR   A4FZB7, PYRH_METM5 ;  A9A6R4, PYRH_METM6 ;  A6VJ20, PYRH_METM7 ;
DR   P59010, PYRH_METMA ;  A3CUB9, PYRH_METMJ ;  Q6M086, PYRH_METMP ;
DR   A2SH96, PYRH_METPP ;  A5UK92, PYRH_METS3 ;  A4YHL6, PYRH_METS5 ;
DR   Q2NEL4, PYRH_METST ;  O26965, PYRH_METTH ;  A0B8B0, PYRH_METTP ;
DR   A6URZ7, PYRH_METVS ;  Q2RJP1, PYRH_MOOTA ;  A0QJ19, PYRH_MYCA1 ;
DR   P65930, PYRH_MYCBO ;  A1KMM7, PYRH_MYCBP ;  Q2SSA5, PYRH_MYCCT ;
DR   Q7NC20, PYRH_MYCGA ;  P47672, PYRH_MYCGE ;  Q600A4, PYRH_MYCH2 ;
DR   Q4A7I8, PYRH_MYCH7 ;  Q4A9E9, PYRH_MYCHJ ;  O33045, PYRH_MYCLE ;
DR   Q6KIN6, PYRH_MYCMO ;  Q73VR6, PYRH_MYCPA ;  Q8EUG9, PYRH_MYCPE ;
DR   P75165, PYRH_MYCPN ;  Q98QZ0, PYRH_MYCPU ;  A0QVD9, PYRH_MYCS2 ;
DR   Q4A587, PYRH_MYCS5 ;  A3PXZ4, PYRH_MYCSJ ;  A1UEJ0, PYRH_MYCSK ;
DR   Q1BAH2, PYRH_MYCSS ;  A5U6N8, PYRH_MYCTA ;  P65929, PYRH_MYCTU ;
DR   A1T784, PYRH_MYCVP ;  Q1D1I1, PYRH_MYXXD ;  Q3IRL6, PYRH_NATPD ;
DR   Q5F5F5, PYRH_NEIG1 ;  P65931, PYRH_NEIMA ;  P65932, PYRH_NEIMB ;
DR   A1KWH8, PYRH_NEIMF ;  Q2GCI6, PYRH_NEOSM ;  Q0AEH6, PYRH_NITEC ;
DR   Q82TZ7, PYRH_NITEU ;  Q1QMN5, PYRH_NITHX ;  Q2YBA5, PYRH_NITMU ;
DR   Q3JCX3, PYRH_NITOC ;  A6Q311, PYRH_NITSB ;  Q3SRH4, PYRH_NITWN ;
DR   Q5YS63, PYRH_NOCFA ;  A1SLQ8, PYRH_NOCSJ ;  Q8YXK5, PYRH_NOSS1 ;
DR   Q2G8K8, PYRH_NOVAD ;  Q8EQV1, PYRH_OCEIH ;  A6X0J3, PYRH_OCHA4 ;
DR   Q04F86, PYRH_OENOB ;  Q6YR50, PYRH_ONYPE ;  A5CD80, PYRH_ORITB ;
DR   A6LHB0, PYRH_PARD8 ;  A1B965, PYRH_PARDP ;  A7HY17, PYRH_PARL1 ;
DR   Q6M9Z8, PYRH_PARUW ;  P59005, PYRH_PARZE ;  Q9CJL5, PYRH_PASMU ;
DR   Q03FT4, PYRH_PEDPA ;  Q3A397, PYRH_PELCD ;  Q3B5T8, PYRH_PELLD ;
DR   A1AQN4, PYRH_PELPD ;  Q7N8P5, PYRH_PHOLL ;  Q6LN26, PYRH_PHOPR ;
DR   Q6KZ23, PYRH_PICTO ;  A1VN42, PYRH_POLNA ;  Q12A33, PYRH_POLSJ ;
DR   Q7MTP5, PYRH_PORGI ;  Q6A7J9, PYRH_PROAC ;  A3PBP6, PYRH_PROM0 ;
DR   A2C0Y1, PYRH_PROM1 ;  A8G3N7, PYRH_PROM2 ;  A2C7Q3, PYRH_PROM3 ;
DR   A2BVI4, PYRH_PROM5 ;  Q31C12, PYRH_PROM9 ;  Q7VD61, PYRH_PROMA ;
DR   Q7V6C2, PYRH_PROMM ;  Q7V2F8, PYRH_PROMP ;  A2BQ03, PYRH_PROMS ;
DR   Q46GQ4, PYRH_PROMT ;  Q48F61, PYRH_PSE14 ;  Q15WG1, PYRH_PSEA6 ;
DR   A6V1D4, PYRH_PSEA7 ;  Q02RC6, PYRH_PSEAB ;  O82852, PYRH_PSEAE ;
DR   Q1I628, PYRH_PSEE4 ;  Q4KHH4, PYRH_PSEF5 ;  Q3IIX6, PYRH_PSEHT ;
DR   A4XWT9, PYRH_PSEMY ;  A5W848, PYRH_PSEP1 ;  Q3KHB0, PYRH_PSEPF ;
DR   Q88MH8, PYRH_PSEPK ;  Q886P1, PYRH_PSESM ;  Q4ZWS6, PYRH_PSEU2 ;
DR   A4VJS3, PYRH_PSEU5 ;  Q4FRH5, PYRH_PSYA2 ;  Q1QA12, PYRH_PSYCK ;
DR   A1SYW1, PYRH_PSYIN ;  A5WGF1, PYRH_PSYWF ;  Q9V0P2, PYRH_PYRAB ;
DR   Q8ZTP3, PYRH_PYRAE ;  A4WLE9, PYRH_PYRAR ;  A3MX54, PYRH_PYRCJ ;
DR   Q8U122, PYRH_PYRFU ;  O50116, PYRH_PYRHO ;  A1RRX6, PYRH_PYRIL ;
DR   Q5JFZ7, PYRH_PYRKO ;  Q1LNF6, PYRH_RALME ;  Q8XZI9, PYRH_RALSO ;
DR   Q2K8Y5, PYRH_RHIEC ;  Q1MH52, PYRH_RHIL3 ;  Q98MB7, PYRH_RHILO ;
DR   Q92Q53, PYRH_RHIME ;  Q7UTH1, PYRH_RHOBA ;  Q21WY7, PYRH_RHOFD ;
DR   Q2IW82, PYRH_RHOP2 ;  Q07NJ1, PYRH_RHOP5 ;  Q6N5Q3, PYRH_RHOPA ;
DR   Q215E7, PYRH_RHOPB ;  Q136A6, PYRH_RHOPS ;  Q2RU07, PYRH_RHORT ;
DR   A3PJF6, PYRH_RHOS1 ;  Q3J2X5, PYRH_RHOS4 ;  A4WUH9, PYRH_RHOS5 ;
DR   Q0S283, PYRH_RHOSR ;  A8GMC4, PYRH_RICAH ;  A8GV49, PYRH_RICB8 ;
DR   Q1RHF2, PYRH_RICBR ;  A8EXM4, PYRH_RICCK ;  Q92J71, PYRH_RICCN ;
DR   Q4UKF4, PYRH_RICFE ;  A8F0R3, PYRH_RICM5 ;  Q9ZE07, PYRH_RICPR ;
DR   A8GQY1, PYRH_RICRS ;  Q68XL3, PYRH_RICTY ;  Q166F6, PYRH_ROSDO ;
DR   A5UUV0, PYRH_ROSS1 ;  Q1AW66, PYRH_RUBXD ;  A1AVT7, PYRH_RUTMC ;
DR   Q21HH4, PYRH_SACD2 ;  A4FMD5, PYRH_SACEN ;  Q57T37, PYRH_SALCH ;
DR   Q5PD61, PYRH_SALPA ;  Q2S6J2, PYRH_SALRD ;  P65934, PYRH_SALTI ;
DR   P65933, PYRH_SALTY ;  A8GIE4, PYRH_SERP5 ;  A1S4P2, PYRH_SHEAM ;
DR   A3D2K7, PYRH_SHEB5 ;  A6WLA8, PYRH_SHEB8 ;  Q12NY5, PYRH_SHEDO ;
DR   Q085E0, PYRH_SHEFN ;  A3QGA1, PYRH_SHELP ;  Q8EGH3, PYRH_SHEON ;
DR   A4Y545, PYRH_SHEPC ;  A0KZ21, PYRH_SHESA ;  Q0HGV7, PYRH_SHESM ;
DR   Q0HT64, PYRH_SHESR ;  A1RLM5, PYRH_SHESW ;  Q325W9, PYRH_SHIBS ;
DR   Q32JT8, PYRH_SHIDS ;  Q0T838, PYRH_SHIF8 ;  P0A7F2, PYRH_SHIFL ;
DR   Q3Z5I7, PYRH_SHISS ;  Q5LSV4, PYRH_SILPO ;  Q1GGR9, PYRH_SILST ;
DR   A6U8K4, PYRH_SINMW ;  Q2NRK9, PYRH_SODGM ;  Q02AL3, PYRH_SOLUE ;
DR   Q1GRQ2, PYRH_SPHAL ;  A5V3G4, PYRH_SPHWW ;  A7X1N6, PYRH_STAA1 ;
DR   Q2FHI0, PYRH_STAA3 ;  Q2FZ22, PYRH_STAA8 ;  Q2YXL0, PYRH_STAAB ;
DR   Q5HGH3, PYRH_STAAC ;  A6QGF8, PYRH_STAAE ;  P65935, PYRH_STAAM ;
DR   P65936, PYRH_STAAN ;  Q6GHH7, PYRH_STAAR ;  Q6G9V5, PYRH_STAAS ;
DR   P65937, PYRH_STAAW ;  Q5HPT3, PYRH_STAEQ ;  Q8CSU1, PYRH_STAES ;
DR   Q4L5W0, PYRH_STAHJ ;  A3DMM2, PYRH_STAMF ;  Q49X43, PYRH_STAS1 ;
DR   Q3K010, PYRH_STRA1 ;  Q8E431, PYRH_STRA3 ;  Q8DYG8, PYRH_STRA5 ;
DR   Q82JX9, PYRH_STRAW ;  O69913, PYRH_STRCO ;  A8AY71, PYRH_STRGC ;
DR   Q8DSY1, PYRH_STRMU ;  P65938, PYRH_STRP1 ;  Q04KY1, PYRH_STRP2 ;
DR   P0DD72, PYRH_STRP3 ;  Q5XDH4, PYRH_STRP6 ;  P65940, PYRH_STRP8 ;
DR   Q1JD59, PYRH_STRPB ;  Q1JN32, PYRH_STRPC ;  Q1JI78, PYRH_STRPD ;
DR   Q1J833, PYRH_STRPF ;  A2RG31, PYRH_STRPG ;  Q48UX7, PYRH_STRPM ;
DR   Q97R83, PYRH_STRPN ;  P0DD73, PYRH_STRPQ ;  Q8DQ50, PYRH_STRR6 ;
DR   A4W2B2, PYRH_STRS2 ;  A3CPA3, PYRH_STRSV ;  A4VW04, PYRH_STRSY ;
DR   Q5M141, PYRH_STRT1 ;  Q5M5N0, PYRH_STRT2 ;  Q03M16, PYRH_STRTD ;
DR   Q4J986, PYRH_SULAC ;  Q30SN5, PYRH_SULDN ;  C3N5A5, PYRH_SULIA ;
DR   C4KGX1, PYRH_SULIK ;  C3MPM9, PYRH_SULIL ;  C3MYM3, PYRH_SULIM ;
DR   C3NHU4, PYRH_SULIN ;  C3NDV9, PYRH_SULIY ;  A6QB35, PYRH_SULNB ;
DR   Q97ZE2, PYRH_SULSO ;  Q971S6, PYRH_SULTO ;  Q67PB5, PYRH_SYMTH ;
DR   Q2LTQ5, PYRH_SYNAS ;  Q31QY1, PYRH_SYNE7 ;  A0LJ65, PYRH_SYNFM ;
DR   Q2JS42, PYRH_SYNJA ;  Q2JJE2, PYRH_SYNJB ;  Q5N3B6, PYRH_SYNP6 ;
DR   A5GJF0, PYRH_SYNPW ;  Q7U5F5, PYRH_SYNPX ;  A5GSA3, PYRH_SYNR3 ;
DR   Q0I8L5, PYRH_SYNS3 ;  Q3AV98, PYRH_SYNS9 ;  Q3ALP7, PYRH_SYNSC ;
DR   Q0AYK2, PYRH_SYNWW ;  P74457, PYRH_SYNY3 ;  Q9HKV7, PYRH_THEAC ;
DR   Q8DM63, PYRH_THEEB ;  Q47S51, PYRH_THEFY ;  C5A3Q1, PYRH_THEGJ ;
DR   A8F5E8, PYRH_THELT ;  A6LK98, PYRH_THEM4 ;  Q9X1U0, PYRH_THEMA ;
DR   B1Y9Y6, PYRH_THENV ;  B6YXE5, PYRH_THEON ;  A5ILX9, PYRH_THEP1 ;
DR   A1RXJ4, PYRH_THEPD ;  C6A429, PYRH_THESM ;  Q72KD9, PYRH_THET2 ;
DR   P43891, PYRH_THET8 ;  Q8RA23, PYRH_THETN ;  Q97B72, PYRH_THEVO ;
DR   Q31G45, PYRH_THICR ;  Q3SKN7, PYRH_THIDA ;  Q10Y48, PYRH_TRIEI ;
DR   Q83HZ6, PYRH_TROW8 ;  Q83G72, PYRH_TROWT ;  Q0W3K6, PYRH_UNCMA ;
DR   Q9PPX6, PYRH_UREPA ;  A1WHU4, PYRH_VEREI ;  A5CXD7, PYRH_VESOH ;
DR   A5F619, PYRH_VIBC3 ;  Q9KPV4, PYRH_VIBCH ;  Q5E3E1, PYRH_VIBF1 ;
DR   A7N1X5, PYRH_VIBHB ;  Q87ME0, PYRH_VIBPA ;  Q8DBF9, PYRH_VIBVU ;
DR   Q7MIG2, PYRH_VIBVY ;  Q8D2G4, PYRH_WIGBR ;  Q73HM2, PYRH_WOLPM ;
DR   Q7MAH8, PYRH_WOLSU ;  Q5GRI0, PYRH_WOLTR ;  P59008, PYRH_XANAC ;
DR   Q3BVK6, PYRH_XANC5 ;  Q4USQ8, PYRH_XANC8 ;  P59009, PYRH_XANCP ;
DR   Q2P4A8, PYRH_XANOM ;  Q5H1E3, PYRH_XANOR ;  Q9PEH0, PYRH_XYLFA ;
DR   Q87EH1, PYRH_XYLFT ;  A1JP80, PYRH_YERE8 ;  A7FFH1, PYRH_YERP3 ;
DR   Q1CAN2, PYRH_YERPA ;  Q8ZH64, PYRH_YERPE ;  Q1CFE9, PYRH_YERPN ;
DR   A4TL89, PYRH_YERPP ;  Q667J1, PYRH_YERPS ;  Q9X5E9, PYRH_ZYMMO ;
//
ID   2.7.4.23
DE   Ribose 1,5-bisphosphate phosphokinase.
AN   Ribose 1,5-bisphosphokinase.
CA   ATP + ribose 1,5-bisphosphate = ADP + 5-phospho-alpha-D-ribose
CA   1-diphosphate.
CC   -!- This enzyme, found in NAD suppression mutants of Escherichia coli,
CC       synthesizes 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) without the
CC       participation of EC 2.7.6.1.
CC   -!- Ribose, ribose 1-phosphate and ribose 5-phosphate are not substrates,
CC       and GTP cannot act as a phosphate donor.
DR   E3HQ85, PHNN_ACHXA ;  A5G2M7, PHNN_ACICJ ;  A9CKM5, PHNN_AGRT5 ;
DR   C1DLT0, PHNN_AZOVD ;  Q89V30, PHNN_BRAJA ;  Q57D38, PHNN_BRUAB ;
DR   C0RJ73, PHNN_BRUMB ;  A1V0B1, PHNN_BURMS ;  Q63R14, PHNN_BURPS ;
DR   Q7NWY0, PHNN_CHRVO ;  C7LNQ3, PHNN_DESBD ;  D2C357, PHNN_DICD5 ;
DR   Q8X5P4, PHNN_ECO57 ;  P16690, PHNN_ECOLI ;  B1LPR3, PHNN_ECOSM ;
DR   E3G1M3, PHNN_ENTCS ;  Q6D9W6, PHNN_ERWCT ;  E3J0E1, PHNN_FRASU ;
DR   A6SU94, PHNN_JANMA ;  A6TH13, PHNN_KLEP7 ;  C1D7Y5, PHNN_LARHH ;
DR   Q11C47, PHNN_MESSB ;  B1LY53, PHNN_METRJ ;  E1SHE4, PHNN_PANVC ;
DR   D0KG93, PHNN_PECWW ;  A6V255, PHNN_PSEA7 ;  C3K5M3, PHNN_PSEFS ;
DR   A1T0U7, PHNN_PSYIN ;  B3PXI8, PHNN_RHIE6 ;  Q6NBY8, PHNN_RHOPA ;
DR   A9MGI9, PHNN_SALAR ;  Q329H3, PHNN_SHIDS ;  Q1GL02, PHNN_SILST ;
DR   Q3SGK8, PHNN_THIDA ;  Q7CKG8, PHNN_YERPE ;  A8IA58, RBKTP_AZOC5;
DR   Q0K3R9, RBKTP_CUPNH;  Q46UT0, RBKTP_CUPPJ;  B2AIF3, RBKTP_CUPTR;
DR   Q16A32, RBKTP_ROSDO;
//
ID   2.7.4.24
DE   Diphosphoinositol-pentakisphosphate kinase.
AN   Diphosphoinositol pentakisphosphate kinase.
AN   PP-IP(5) kinase.
CA   ATP + 1D-myo-inositol 5-diphosphate pentakisphosphate = ADP + 1D-myo-
CA   inositol bisdiphosphate tetrakisphosphate (isomeric configuration
CA   unknown).
CC   -!- Activated by osmotic shock.
CC   -!- Can also phosphorylate InsP(6), but more slowly.
CC   -!- Ins(1,3,4,5,6)P(5), POP-InsP(4) and (POP)2-InsP(3) are not
CC       substrates.
CC   -!- Formerly EC 2.7.1.155.
DR   A7Z050, VIP1_BOVIN ;  P91309, VIP1_CAEEL ;  Q9VR59, VIP1_DROME ;
DR   Q6PFW1, VIP1_HUMAN ;  A2ARP1, VIP1_MOUSE ;  Q5RDF1, VIP1_PONAB ;
DR   P0C644, VIP1_RAT   ;  O74429, VIP1_SCHPO ;  Q06685, VIP1_YEAST ;
DR   O43314, VIP2_HUMAN ;  Q6ZQB6, VIP2_MOUSE ;  Q5REW0, VIP2_PONAB ;
DR   Q5XHF8, VIP2_XENLA ;
//
ID   2.7.4.25
DE   (d)CMP kinase.
AN   dCMP kinase.
AN   Deoxycytidine monophosphokinase.
AN   Deoxycytidylate kinase.
CA   ATP + (d)CMP = ADP + (d)CDP.
CC   -!- The prokaryotic cytidine monophosphate kinase specifically
CC       phosphorylates CMP (or dCMP), using ATP as the preferred phosphoryl
CC       donor.
CC   -!- Unlike EC 2.7.4.14, a eukaryotic enzyme that phosphorylates UMP and
CC       CMP with similar efficiency, the prokaryotic enzyme phosphorylates
CC       UMP with very low rates, and this function is catalyzed in
CC       prokaryotes by EC 2.7.4.22.
CC   -!- The enzyme phosphorylates dCMP nearly as well as it does CMP.
//
ID   2.7.5.1
DE   Transferred entry: 5.4.2.2.
//
ID   2.7.5.2
DE   Transferred entry: 5.4.2.3.
//
ID   2.7.5.3
DE   Transferred entry: 5.4.2.1.
//
ID   2.7.5.4
DE   Transferred entry: 5.4.2.4.
//
ID   2.7.5.5
DE   Transferred entry: 5.4.2.5.
//
ID   2.7.5.6
DE   Transferred entry: 5.4.2.7.
//
ID   2.7.5.7
DE   Transferred entry: 5.4.2.8.
//
ID   2.7.6.1
DE   Ribose-phosphate diphosphokinase.
AN   Phosphoribosyl diphosphate synthetase.
AN   Phosphoribosyl pyrophosphate synthetase.
AN   Ribose-phosphate pyrophosphokinase.
CA   ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose
CA   1-diphosphate.
CC   -!- dATP can also act as donor.
PR   PROSITE; PDOC00105;
DR   P46585, KPR1_CANAL ;  P41831, KPR1_SCHPO ;  P32895, KPR1_YEAST ;
DR   P38620, KPR2_YEAST ;  O94413, KPR3_SCHPO ;  P38689, KPR3_YEAST ;
DR   P87171, KPR4_SCHPO ;  P38063, KPR4_YEAST ;  Q12265, KPR5_YEAST ;
DR   Q9EWS0, KPRH_STRCO ;  Q42581, KPRS1_ARATH;  O29666, KPRS1_ARCFU;
DR   Q82ZA5, KPRS1_ENTFA;  Q9CHB8, KPRS1_LACLA;  Q88Z84, KPRS1_LACPL;
DR   Q92F68, KPRS1_LISIN;  Q83YI7, KPRS1_LISIV;  Q724L4, KPRS1_LISMF;
DR   Q48793, KPRS1_LISMO;  Q83TK1, KPRS1_LISWE;  Q6Z2L5, KPRS1_ORYSJ;
DR   Q9XG98, KPRS1_SPIOL;  Q8E7X8, KPRS1_STRA3;  Q8E2H0, KPRS1_STRA5;
DR   Q8DWM2, KPRS1_STRMU;  P65243, KPRS1_STRP1;  P0DB98, KPRS1_STRP3;
DR   Q5XEL0, KPRS1_STRP6;  P65245, KPRS1_STRP8;  P65239, KPRS1_STRPN;
DR   P0DB99, KPRS1_STRPQ;  P65240, KPRS1_STRR6;  Q42583, KPRS2_ARATH;
DR   O28853, KPRS2_ARCFU;  Q832Z5, KPRS2_ENTFA;  Q9CEI4, KPRS2_LACLA;
DR   Q88VA5, KPRS2_LACPL;  Q92EF1, KPRS2_LISIN;  Q723E1, KPRS2_LISMF;
DR   Q8Y9L8, KPRS2_LISMO;  Q69XQ6, KPRS2_ORYSJ;  Q9XG99, KPRS2_SPIOL;
DR   Q8E568, KPRS2_STRA3;  Q8DZK4, KPRS2_STRA5;  Q8DU94, KPRS2_STRMU;
DR   Q99ZR0, KPRS2_STRP1;  P0DC00, KPRS2_STRP3;  Q5XC85, KPRS2_STRP6;
DR   Q8P137, KPRS2_STRP8;  P65241, KPRS2_STRPN;  P0DC01, KPRS2_STRPQ;
DR   P65242, KPRS2_STRR6;  Q93Z66, KPRS3_ARATH;  Q8S2E5, KPRS3_ORYSJ;
DR   Q9XGA0, KPRS3_SPIOL;  Q680A5, KPRS4_ARATH;  Q6ZFT5, KPRS4_ORYSJ;
DR   Q9XGA1, KPRS4_SPIOL;  O64888, KPRS5_ARATH;  Q9YAW0, KPRS_AERPE ;
DR   Q8UDA9, KPRS_AGRT5 ;  O67556, KPRS_AQUAE ;  Q81VZ0, KPRS_BACAN ;
DR   P42816, KPRS_BACCL ;  Q81J97, KPRS_BACCR ;  Q9KGJ5, KPRS_BACHD ;
DR   P14193, KPRS_BACSU ;  Q1LTH2, KPRS_BAUCH ;  Q8G5P2, KPRS_BIFLO ;
DR   Q7VR76, KPRS_BLOFL ;  Q7WNY4, KPRS_BORBR ;  Q7W181, KPRS_BORPA ;
DR   Q7VUH1, KPRS_BORPE ;  Q89DJ1, KPRS_BRAJA ;  Q8YIG1, KPRS_BRUME ;
DR   Q8FZF0, KPRS_BRUSU ;  P57266, KPRS_BUCAI ;  Q8K9X2, KPRS_BUCAP ;
DR   P59512, KPRS_BUCBP ;  Q9PP15, KPRS_CAMJE ;  B8GZV1, KPRS_CAUCN ;
DR   Q9AAV6, KPRS_CAUCR ;  Q8KCQ2, KPRS_CHLTE ;  Q7NQS9, KPRS_CHRVO ;
DR   Q97E93, KPRS_CLOAB ;  Q8XHJ4, KPRS_CLOPE ;  Q899I8, KPRS_CLOTE ;
DR   O33924, KPRS_CORAM ;  Q8FQV2, KPRS_COREF ;  Q8NRU9, KPRS_CORGL ;
DR   Q83AQ1, KPRS_COXBU ;  Q9RUD2, KPRS_DEIRA ;  Q6AJL7, KPRS_DESPS ;
DR   P0A719, KPRS_ECO57 ;  P0A718, KPRS_ECOL6 ;  P0A717, KPRS_ECOLI ;
DR   Q8RHM2, KPRS_FUSNN ;  Q7NM67, KPRS_GLOVI ;  Q0BPP0, KPRS_GRABC ;
DR   Q7VL55, KPRS_HAEDU ;  P44328, KPRS_HAEIN ;  B0R7B4, KPRS_HALS3 ;
DR   Q9HN88, KPRS_HALSA ;  Q7VFY9, KPRS_HELHP ;  Q9ZLA1, KPRS_HELPJ ;
DR   P56184, KPRS_HELPY ;  Q0C5A1, KPRS_HYPNA ;  Q72V73, KPRS_LEPIC ;
DR   Q8EZN0, KPRS_LEPIN ;  Q0ARN5, KPRS_MARMM ;  A6W1C7, KPRS_MARMS ;
DR   Q8TRK8, KPRS_METAC ;  Q58761, KPRS_METJA ;  Q8TUT6, KPRS_METKA ;
DR   Q8PUX3, KPRS_METMA ;  A5UNK4, KPRS_METS3 ;  O26877, KPRS_METTH ;
DR   P65233, KPRS_MYCBO ;  P47304, KPRS_MYCGE ;  Q9CD45, KPRS_MYCLE ;
DR   P75044, KPRS_MYCPN ;  Q98R83, KPRS_MYCPU ;  P65232, KPRS_MYCTU ;
DR   P65234, KPRS_NEIMA ;  P65235, KPRS_NEIMB ;  Q82TQ4, KPRS_NITEU ;
DR   Q8YN97, KPRS_NOSS1 ;  Q8EU34, KPRS_OCEIH ;  Q9CP22, KPRS_PASMU ;
DR   Q7N590, KPRS_PHOLL ;  Q7MT83, KPRS_PORGI ;  Q7VBH4, KPRS_PROMA ;
DR   Q7V6S2, KPRS_PROMM ;  Q7V111, KPRS_PROMP ;  Q9HVC5, KPRS_PSEAE ;
DR   Q88PX6, KPRS_PSEPK ;  Q888C6, KPRS_PSESM ;  Q9UY08, KPRS_PYRAB ;
DR   Q8ZU24, KPRS_PYRAE ;  Q8U458, KPRS_PYRFU ;  O59586, KPRS_PYRHO ;
DR   O52958, KPRS_PYRKO ;  Q8Y2E1, KPRS_RALSO ;  Q98HW3, KPRS_RHILO ;
DR   Q92N73, KPRS_RHIME ;  Q7UPM4, KPRS_RHOBA ;  B9KPJ0, KPRS_RHOSK ;
DR   P0A1V7, KPRS_SALTI ;  P0A1V6, KPRS_SALTY ;  Q8EAQ9, KPRS_SHEON ;
DR   Q5HIH5, KPRS_STAAC ;  P65236, KPRS_STAAM ;  P65237, KPRS_STAAN ;
DR   Q6GJH1, KPRS_STAAR ;  Q6GBY8, KPRS_STAAS ;  P65238, KPRS_STAAW ;
DR   Q5HRQ5, KPRS_STAEQ ;  Q8CQU7, KPRS_STAES ;  Q4L3F7, KPRS_STAHJ ;
DR   Q49V09, KPRS_STAS1 ;  Q82HE7, KPRS_STRAW ;  Q9K3U0, KPRS_STRCO ;
DR   Q4J9A6, KPRS_SULAC ;  Q97Z86, KPRS_SULSO ;  Q973F3, KPRS_SULTO ;
DR   Q59988, KPRS_SYNE7 ;  Q7U7L5, KPRS_SYNPX ;  Q55848, KPRS_SYNY3 ;
DR   B7IFM5, KPRS_THEAB ;  Q9HLV6, KPRS_THEAC ;  Q9X1W3, KPRS_THEMA ;
DR   Q8R753, KPRS_THETN ;  Q97CA5, KPRS_THEVO ;  Q9PQV0, KPRS_UREPA ;
DR   Q9KQ22, KPRS_VIBCH ;  Q87RN8, KPRS_VIBPA ;  Q8DFF5, KPRS_VIBVU ;
DR   Q7MMZ1, KPRS_VIBVY ;  Q7M8J0, KPRS_WOLSU ;  Q8PNU0, KPRS_XANAC ;
DR   Q8PC63, KPRS_XANCP ;  Q9PA76, KPRS_XYLFA ;  Q87A22, KPRS_XYLFT ;
DR   Q8ZEY2, KPRS_YERPE ;  Q2HJ58, PRPS1_BOVIN;  P60891, PRPS1_HUMAN;
DR   Q4R4U3, PRPS1_MACFA;  Q9D7G0, PRPS1_MOUSE;  Q5RFJ7, PRPS1_PONAB;
DR   P60892, PRPS1_RAT  ;  Q5ZI49, PRPS2_CHICK;  P11908, PRPS2_HUMAN;
DR   Q4R4R7, PRPS2_MACFA;  Q9CS42, PRPS2_MOUSE;  Q5R8F8, PRPS2_PONAB;
DR   P09330, PRPS2_RAT  ;  Q7ZXC9, PRPS2_XENLA;  Q5XGI0, PRPS2_XENTR;
DR   P21108, PRPS3_HUMAN;  Q54PA9, PRPSA_DICDI;  Q75JN8, PRPSB_DICDI;
DR   Q54QU9, PRPSC_DICDI;
//
ID   2.7.6.2
DE   Thiamine diphosphokinase.
AN   Thiamine kinase.
AN   Thiamine pyrophosphokinase.
CA   ATP + thiamine = AMP + thiamine diphosphate.
DR   P35202, THI80_YEAST;  O34664, THIN_BACSU ;  P41888, TNR3_SCHPO ;
DR   Q5E9T4, TPK1_BOVIN ;  P30636, TPK1_CAEEL ;  Q9H3S4, TPK1_HUMAN ;
DR   Q9R0M5, TPK1_MOUSE ;
//
ID   2.7.6.3
DE   2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase.
AN   2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase.
AN   6-hydroxymethyl-7,8-dihydropterin diphosphokinase.
AN   6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.
AN   7,8-dihydro-6-hydroxymethylpterin diphosphokinase.
AN   7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase.
CA   ATP + 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine = AMP +
CA   (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate.
PR   PROSITE; PDOC00631;
DR   Q54YD9, FOL1_DICDI ;  P29251, FOL1_PNECA ;  Q4LB35, FOL1_SCHPO ;
DR   P53848, FOL1_YEAST ;  Q9CGE3, FOLKE_LACLA;  Q8GJP4, FOLKE_LACLM;
DR   Q821E2, FOLKP_CHLCV;  P82602, FOLKP_CHLMU;  Q9Z7E8, FOLKP_CHLPN;
DR   O84619, FOLKP_CHLTR;  O66550, HPPK_AQUAE ;  P29252, HPPK_BACSU ;
DR   Q9PJ54, HPPK_CAMJE ;  P26281, HPPK_ECOLI ;  P43777, HPPK_HAEIN ;
DR   Q9ZM35, HPPK_HELPJ ;  O25680, HPPK_HELPY ;  P71512, HPPK_METEA ;
DR   P64144, HPPK_MYCBO ;  O69528, HPPK_MYCLE ;  P64143, HPPK_MYCTU ;
DR   B2RI92, HPPK_PORG3 ;  P0C936, HPPK_PORGI ;  Q9HV71, HPPK_PSEAE ;
DR   O87790, HPPK_PSEPU ;  P0C0G3, HPPK_STRP1 ;  P0DB10, HPPK_STRP3 ;
DR   Q5XCA6, HPPK_STRP6 ;  Q8P151, HPPK_STRP8 ;  P0DB11, HPPK_STRPQ ;
DR   P0C0G2, HPPK_STRPY ;  P72736, HPPK_SYNY3 ;  P22291, SULD_STRPN ;
DR   P59657, SULD_STRR6 ;
//
ID   2.7.6.4
DE   Nucleotide diphosphokinase.
AN   Nucleotide pyrophosphokinase.
CA   ATP + nucleoside 5'-phosphate = AMP + 5'-phosphonucleoside
CA   3'-diphosphate.
CC   -!- Acts on the 5'-mono-, di- and triphosphate derivatives of purine
CC       nucleosides.
//
ID   2.7.6.5
DE   GTP diphosphokinase.
AN   GTP pyrophosphokinase.
AN   Guanosine 3',5'-polyphosphate synthase.
AN   ppGpp synthetase I.
AN   Stringent factor.
CA   ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate.
CC   -!- GDP can also act as acceptor.
DR   O54408, RELA_BACSU ;  O87331, RELA_CORGL ;  P0AG22, RELA_ECO57 ;
DR   P0AG21, RELA_ECOL6 ;  P0AG20, RELA_ECOLI ;  P44644, RELA_HAEIN ;
DR   P66015, RELA_MYCBO ;  Q49640, RELA_MYCLE ;  P66014, RELA_MYCTU ;
DR   O52177, RELA_MYXXA ;  P55133, RELA_PHOAS ;  P0AG23, RELA_SHIFL ;
DR   Q931Q4, RELA_STAAM ;  Q99TL8, RELA_STAAN ;  Q6GG70, RELA_STAAR ;
DR   Q6G8T5, RELA_STAAS ;  P0A0F0, RELA_STAAU ;  P0A0E9, RELA_STAAW ;
DR   Q5HNR8, RELA_STAEQ ;  Q8CS97, RELA_STAES ;  O85709, RELA_STRAT ;
DR   P52560, RELA_STRCO ;  Q54089, RELA_STREQ ;  Q2YN11, RSH_BRUA2  ;
DR   Q57E90, RSH_BRUAB  ;  Q8YG65, RSH_BRUME  ;  A5VPI9, RSH_BRUO2  ;
DR   Q8CY42, RSH_BRUSU  ;  P0AG24, SPOT_ECOLI ;  O31611, YJBM_BACSU ;
DR   P39583, YWAC_BACSU ;
//
ID   2.7.7.1
DE   Nicotinamide-nucleotide adenylyltransferase.
AN   Adenosine triphosphate-nicotinamide mononucleotide transadenylase.
AN   Diphosphopyridine nucleotide pyrophosphorylase.
AN   NAD(+) diphosphorylase.
AN   NAD(+) pyrophosphorylase.
AN   Nicotinamide adenine dinucleotide pyrophosphorylase.
AN   Nicotinamide mononucleotide adenylyltransferase.
AN   NMN adenylyltransferase.
AN   NMNAT.
CA   ATP + nicotinamide ribonucleotide = diphosphate + NAD(+).
CC   -!- Nicotinate nucleotide can also act as acceptor.
CC   -!- See also EC 2.7.7.18.
DR   Q4JBW3, NADM1_SULAC;  Q4JAT0, NADM2_SULAC;  Q9YER8, NADM_AERPE ;
DR   O27969, NADM_ARCFU ;  A8M9Z9, NADM_CALMQ ;  B9LMP6, NADM_HALLT ;
DR   Q5V117, NADM_HALMA ;  B0R328, NADM_HALS3 ;  Q9HSC4, NADM_HALSA ;
DR   A8AB26, NADM_IGNH4 ;  A6UTM2, NADM_META3 ;  Q8TJP9, NADM_METAC ;
DR   A7I937, NADM_METB6 ;  Q46FV2, NADM_METBF ;  Q2FTC2, NADM_METHJ ;
DR   Q57961, NADM_METJA ;  A2SS82, NADM_METLZ ;  A4G0Z4, NADM_METM5 ;
DR   A9A983, NADM_METM6 ;  A6VHG6, NADM_METM7 ;  Q8PZ68, NADM_METMA ;
DR   A3CVW1, NADM_METMJ ;  Q6LWX6, NADM_METMP ;  B8GDZ6, NADM_METPE ;
DR   O26253, NADM_METTH ;  Q9UXN8, NADM_METTI ;  A0B5N0, NADM_METTP ;
DR   A6UQM3, NADM_METVS ;  Q6L2T8, NADM_PICTO ;  Q9UYD4, NADM_PYRAB ;
DR   Q8ZX62, NADM_PYRAE ;  A4WHY9, NADM_PYRAR ;  Q8U3K8, NADM_PYRFU ;
DR   O58211, NADM_PYRHO ;  Q5JEF8, NADM_PYRKO ;  P57084, NADM_SULSO ;
DR   Q974L1, NADM_SULTO ;  Q55928, NADM_SYNY3 ;  Q9HK34, NADM_THEAC ;
DR   B1YCL7, NADM_THENV ;  B6YX39, NADM_THEON ;  C6A3E1, NADM_THESM ;
DR   Q97AF1, NADM_THEVO ;  P27278, NADR_ECOLI ;  P44308, NADR_HAEIN ;
DR   P47981, NADR_KLEPN ;  P24518, NADR_SALTY ;  Q06178, NMA1_YEAST ;
DR   P53204, NMA2_YEAST ;  Q9UT53, NMAH_SCHPO ;  Q0VD50, NMNA1_BOVIN;
DR   Q9HAN9, NMNA1_HUMAN;  Q9EPA7, NMNA1_MOUSE;  Q0VC59, NMNA2_BOVIN;
DR   Q6PC93, NMNA2_DANRE;  Q9BZQ4, NMNA2_HUMAN;  Q8BNJ3, NMNA2_MOUSE;
DR   Q5RBL5, NMNA2_PONAB;  Q0HA29, NMNA2_RAT  ;  A4IH61, NMNA2_XENTR;
DR   Q96T66, NMNA3_HUMAN;  Q99JR6, NMNA3_MOUSE;
//
ID   2.7.7.2
DE   FAD synthetase.
AN   FAD diphosphorylase.
AN   FAD pyrophosphorylase.
AN   FADS.
AN   Flavin adenine dinucleotide synthetase.
AN   FMN adenylyltransferase.
CA   ATP + FMN = diphosphate + FAD.
CF   Magnesium.
CC   -!- Highly specific for ATP as phosphate donor.
CC   -!- The cofactors FMN and FAD participate in numerous processes in all
CC       organisms, including mitochondrial electron transport,
CC       photosynthesis, fatty-acid oxidation, and metabolism of vitamin B6,
CC       vitamin B12 and folates.
CC   -!- While monofunctional FAD synthetase is found in eukaryotes and in
CC       some prokaryotes, most prokaryotes have a bifunctional enzyme that
CC       exhibits both this activity and that of EC 2.7.1.26.
DR   Q68EH8, FAD1_DANRE ;  Q8NFF5, FAD1_HUMAN ;  Q8R123, FAD1_MOUSE ;
DR   Q5RCH4, FAD1_PONAB ;  O74841, FAD1_SCHPO ;  P38913, FAD1_YEAST ;
DR   Q626I0, FLAD1_CAEBR;  Q22017, FLAD1_CAEEL;  Q6ING7, FLAD1_XENLA;
DR   Q7NBZ0, MNMA_MYCGA ;  P54575, RIBC_BACSU ;  P57250, RIBF_BUCAI ;
DR   Q8K9Z1, RIBF_BUCAP ;  Q59263, RIBF_CORAM ;  P0AG42, RIBF_ECO57 ;
DR   P0AG41, RIBF_ECOL6 ;  P0AG40, RIBF_ECOLI ;  P44957, RIBF_HAEIN ;
DR   P47391, RIBF_MYCGE ;  P75587, RIBF_MYCPN ;  P22990, RIBF_PSEFL ;
DR   O84990, RIBF_RHOOP ;  P0AG43, RIBF_SHIFL ;  P73651, RIBF_SYNY3 ;
DR   B5I9H4, RIBL_ACIB4 ;  O28854, RIBL_ARCFU ;  D2RES5, RIBL_ARCPA ;
DR   D3RZA9, RIBL_FERPA ;  D8J4S4, RIBL_HALJB ;  B9LSN4, RIBL_HALLT ;
DR   C7P4K0, RIBL_HALMD ;  B0R450, RIBL_HALS3 ;  Q9HRB2, RIBL_HALSA ;
DR   D2RTP8, RIBL_HALTV ;  C7NTR1, RIBL_HALUD ;  D4GVJ2, RIBL_HALVD ;
DR   B1L7J8, RIBL_KORCO ;  A6UWK8, RIBL_META3 ;  Q8TPT5, RIBL_METAC ;
DR   A7I4S0, RIBL_METB6 ;  Q46AS7, RIBL_METBF ;  Q12YR1, RIBL_METBU ;
DR   D7E8Z9, RIBL_METEZ ;  C7P607, RIBL_METFA ;  E3GWN9, RIBL_METFV ;
DR   Q2FT79, RIBL_METHJ ;  D5VUB0, RIBL_METIM ;  Q58579, RIBL_METJA ;
DR   Q8TXT2, RIBL_METKA ;  A2SQH8, RIBL_METLZ ;  A4FXX6, RIBL_METM5 ;
DR   A9AB01, RIBL_METM6 ;  A6VFN4, RIBL_METM7 ;  Q8Q095, RIBL_METMA ;
DR   A3CXW9, RIBL_METMJ ;  Q6LYP5, RIBL_METMP ;  D5EBS7, RIBL_METMS ;
DR   E1RHM5, RIBL_METP4 ;  B8GJN8, RIBL_METPE ;  D1YZF2, RIBL_METPS ;
DR   D3DZ18, RIBL_METRM ;  A5ULI6, RIBL_METS3 ;  D3S3T0, RIBL_METSF ;
DR   Q2NHB2, RIBL_METST ;  O26932, RIBL_METTH ;  D9PX81, RIBL_METTM ;
DR   A0B7A6, RIBL_METTP ;  D7DTT8, RIBL_METV3 ;  C9RF94, RIBL_METVM ;
DR   A6UNT3, RIBL_METVS ;  D3SYU6, RIBL_NATMM ;  Q3IQ95, RIBL_NATPD ;
DR   Q6L0A7, RIBL_PICTO ;  Q9UZ37, RIBL_PYRAB ;  Q8U1T9, RIBL_PYRFU ;
DR   O58466, RIBL_PYRHO ;  Q5JHT4, RIBL_PYRKO ;  Q9HJ34, RIBL_THEAC ;
DR   C5A1S7, RIBL_THEGJ ;  B6YXC8, RIBL_THEON ;  C6A439, RIBL_THESM ;
DR   Q979C2, RIBL_THEVO ;  Q0W933, RIBL_UNCMA ;
//
ID   2.7.7.3
DE   Pantetheine-phosphate adenylyltransferase.
AN   3'-dephospho-CoA pyrophosphorylase.
AN   Dephospho-CoA diphosphorylase.
AN   Dephospho-CoA pyrophosphorylase.
AN   Dephospho-coenzyme A pyrophosphorylase.
AN   Phosphopantetheine adenylyltransferase.
AN   PPAT.
CA   ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA.
CC   -!- The enzyme from several bacteria (e.g. Escherichia coli, Bacillus
CC       subtilis and Haemophilus influenzae) has been shown to be
CC       bifunctional and also to possess the activity of EC 2.3.1.157.
DR   B0CAI3, COAD_ACAM1 ;  Q6F8K0, COAD_ACIAD ;  B2HUN5, COAD_ACIBC ;
DR   B0VTH7, COAD_ACIBS ;  B0V8I3, COAD_ACIBY ;  A0LV90, COAD_ACIC1 ;
DR   A5FXQ8, COAD_ACICJ ;  B9MF03, COAD_ACIET ;  A1WBK4, COAD_ACISJ ;
DR   A3N1D7, COAD_ACTP2 ;  B3GY20, COAD_ACTP7 ;  B0BQ73, COAD_ACTPJ ;
DR   A6VM51, COAD_ACTSZ ;  A0KEN4, COAD_AERHH ;  A4STC9, COAD_AERS4 ;
DR   B9JFA5, COAD_AGRRK ;  Q8UES4, COAD_AGRT5 ;  B9JWW7, COAD_AGRVS ;
DR   Q0A592, COAD_ALHEH ;  B6EPN7, COAD_ALISL ;  A6TRV0, COAD_ALKMQ ;
DR   A8MHA0, COAD_ALKOO ;  P71154, COAD_ALLVD ;  B4S2C7, COAD_ALTMD ;
DR   B8J9D7, COAD_ANAD2 ;  Q2IIM3, COAD_ANADE ;  A7HC22, COAD_ANADF ;
DR   B4UCU5, COAD_ANASK ;  B9MRM3, COAD_ANATD ;  B7GGK2, COAD_ANOFW ;
DR   O66614, COAD_AQUAE ;  Q9ZPV8, COAD_ARATH ;  O28077, COAD_ARCFU ;
DR   Q5P730, COAD_AROAE ;  A1R7I7, COAD_ARTAT ;  B8HAB6, COAD_ARTCA ;
DR   A0JXW3, COAD_ARTS2 ;  A1K3H4, COAD_AZOSB ;  C1DIB2, COAD_AZOVD ;
DR   A7Z4C5, COAD_BACA2 ;  C3P6T7, COAD_BACAA ;  C3LHZ4, COAD_BACAC ;
DR   A0RHU9, COAD_BACAH ;  Q81W43, COAD_BACAN ;  B7JK17, COAD_BACC0 ;
DR   Q732D8, COAD_BACC1 ;  B7IVG6, COAD_BACC2 ;  C1EPU3, COAD_BACC3 ;
DR   B7H6R5, COAD_BACC4 ;  B7HMA9, COAD_BACC7 ;  A7GRV8, COAD_BACCN ;
DR   B9IW07, COAD_BACCQ ;  Q819P1, COAD_BACCR ;  Q635Z7, COAD_BACCZ ;
DR   Q5L7F1, COAD_BACFN ;  Q64MK4, COAD_BACFR ;  Q9K9Q6, COAD_BACHD ;
DR   Q6HEN5, COAD_BACHK ;  Q65JZ9, COAD_BACLD ;  A8FCW1, COAD_BACP2 ;
DR   Q5WFE8, COAD_BACSK ;  O34797, COAD_BACSU ;  Q8A3C0, COAD_BACTN ;
DR   A6KZR2, COAD_BACV8 ;  A9VU91, COAD_BACWK ;  Q8RT67, COAD_BARBK ;
DR   Q6G304, COAD_BARHE ;  Q6FZG1, COAD_BARQU ;  A9IVT5, COAD_BART1 ;
DR   Q6MQ60, COAD_BDEBA ;  B2IHR4, COAD_BEII9 ;  B8DVS0, COAD_BIFA0 ;
DR   B3DTL4, COAD_BIFLD ;  Q8G7H5, COAD_BIFLO ;  B7GN19, COAD_BIFLS ;
DR   Q491X2, COAD_BLOPB ;  Q2KY40, COAD_BORA1 ;  Q0SMF3, COAD_BORAP ;
DR   Q7WNU4, COAD_BORBR ;  O51645, COAD_BORBU ;  B7J0E9, COAD_BORBZ ;
DR   B5RMP6, COAD_BORDL ;  Q660H0, COAD_BORGA ;  B2S145, COAD_BORHD ;
DR   Q7W154, COAD_BORPA ;  A9I6L9, COAD_BORPD ;  Q7VTP4, COAD_BORPE ;
DR   B5RQ42, COAD_BORRA ;  A1R0C7, COAD_BORT9 ;  C0R0Q0, COAD_BRAHW ;
DR   Q89L55, COAD_BRAJA ;  A5EJR7, COAD_BRASB ;  A4YV23, COAD_BRASO ;
DR   B2S5U8, COAD_BRUA1 ;  Q2YPY4, COAD_BRUA2 ;  Q57D42, COAD_BRUAB ;
DR   A9M5A7, COAD_BRUC2 ;  C0RJ68, COAD_BRUMB ;  P63814, COAD_BRUME ;
DR   A5VQM2, COAD_BRUO2 ;  B0CGP5, COAD_BRUSI ;  P63815, COAD_BRUSU ;
DR   B8D8E6, COAD_BUCA5 ;  P57643, COAD_BUCAI ;  Q9Z613, COAD_BUCAP ;
DR   B8D8A3, COAD_BUCAT ;  B1YN57, COAD_BURA4 ;  Q1BTG1, COAD_BURCA ;
DR   B1JYQ4, COAD_BURCC ;  A0KAN0, COAD_BURCH ;  B4EAQ8, COAD_BURCJ ;
DR   Q0BBQ0, COAD_BURCM ;  A9AEW9, COAD_BURM1 ;  A3MQB0, COAD_BURM7 ;
DR   A2S6B1, COAD_BURM9 ;  Q62FB8, COAD_BURMA ;  A1UZP1, COAD_BURMS ;
DR   A3NR92, COAD_BURP0 ;  Q3JW91, COAD_BURP1 ;  A3N5J6, COAD_BURP6 ;
DR   B2JCN4, COAD_BURP8 ;  B2SXG0, COAD_BURPP ;  Q63XM3, COAD_BURPS ;
DR   Q39CT5, COAD_BURS3 ;  Q2T1C2, COAD_BURTA ;  A4JI00, COAD_BURVG ;
DR   Q145X7, COAD_BURXL ;  A4XKE2, COAD_CALS8 ;  A7ZDJ9, COAD_CAMC1 ;
DR   A7GYG9, COAD_CAMC5 ;  A0RPD1, COAD_CAMFF ;  A7I1U3, COAD_CAMHC ;
DR   A8FLI0, COAD_CAMJ8 ;  A7H475, COAD_CAMJD ;  Q9PPF2, COAD_CAMJE ;
DR   A1VZB5, COAD_CAMJJ ;  Q5HV25, COAD_CAMJR ;  Q3AC43, COAD_CARHZ ;
DR   B8GVE7, COAD_CAUCN ;  P58103, COAD_CAUCR ;  B0SZS4, COAD_CAUSK ;
DR   A9WH99, COAD_CHLAA ;  B8G6P2, COAD_CHLAD ;  Q3AQM9, COAD_CHLCH ;
DR   B3ECH9, COAD_CHLL2 ;  B3QNZ9, COAD_CHLP8 ;  B3EQL4, COAD_CHLPB ;
DR   A1BF85, COAD_CHLPD ;  B9LJG5, COAD_CHLSY ;  Q8KDS9, COAD_CHLTE ;
DR   Q1QTC8, COAD_CHRSD ;  Q7NZ19, COAD_CHRVO ;  A8ARM1, COAD_CITK8 ;
DR   A5CQP6, COAD_CLAM3 ;  B0REL6, COAD_CLAMS ;  Q97IB2, COAD_CLOAB ;
DR   A7FW59, COAD_CLOB1 ;  C3L0J4, COAD_CLOB6 ;  A6LSL2, COAD_CLOB8 ;
DR   B2V4C6, COAD_CLOBA ;  B2TJ12, COAD_CLOBB ;  A5I4S1, COAD_CLOBH ;
DR   C1FSR3, COAD_CLOBJ ;  B1IIK4, COAD_CLOBK ;  A7GG79, COAD_CLOBL ;
DR   B1KX43, COAD_CLOBM ;  B8I385, COAD_CLOCE ;  B9E1F8, COAD_CLOK1 ;
DR   A5N7Z7, COAD_CLOK5 ;  A0Q101, COAD_CLONN ;  Q0TPM5, COAD_CLOP1 ;
DR   Q8XJM7, COAD_CLOPE ;  A9KNU8, COAD_CLOPH ;  Q0SS92, COAD_CLOPS ;
DR   Q895N8, COAD_CLOTE ;  A3DEX9, COAD_CLOTH ;  B5Y7V9, COAD_COPPD ;
DR   Q6NHJ8, COAD_CORDI ;  Q8FPP9, COAD_COREF ;  A4QDU2, COAD_CORGB ;
DR   Q8NQU5, COAD_CORGL ;  B6J5S3, COAD_COXB1 ;  B6J216, COAD_COXB2 ;
DR   A9KCX4, COAD_COXBN ;  A9NB23, COAD_COXBR ;  Q83EM7, COAD_COXBU ;
DR   Q0KEQ3, COAD_CUPNH ;  Q476G3, COAD_CUPPJ ;  B2AGT3, COAD_CUPTR ;
DR   B1WS35, COAD_CYAA5 ;  B8HPS4, COAD_CYAP4 ;  B7KEW8, COAD_CYAP7 ;
DR   Q11RP5, COAD_CYTH3 ;  Q3ZA11, COAD_DEHE1 ;  A5FSN4, COAD_DEHSB ;
DR   Q3ZWQ5, COAD_DEHSC ;  C1CY24, COAD_DEIDV ;  Q1J1P5, COAD_DEIGD ;
DR   Q9RWM4, COAD_DEIRA ;  B8FI62, COAD_DESAA ;  C6BXG1, COAD_DESAD ;
DR   B1I2E4, COAD_DESAP ;  Q310R6, COAD_DESDG ;  B8FTK5, COAD_DESHD ;
DR   Q24XZ0, COAD_DESHY ;  C4XSE1, COAD_DESMR ;  A8ZXR7, COAD_DESOH ;
DR   Q6AJH7, COAD_DESPS ;  A4J698, COAD_DESRM ;  Q72BV2, COAD_DESVH ;
DR   A1VDV0, COAD_DESVV ;  A5EXY9, COAD_DICNV ;  B5YEA6, COAD_DICT6 ;
DR   B8E2S1, COAD_DICTD ;  A8LME1, COAD_DINSH ;  A7ZTI5, COAD_ECO24 ;
DR   B7ULI9, COAD_ECO27 ;  B7MFJ5, COAD_ECO45 ;  B7L747, COAD_ECO55 ;
DR   P0A6I7, COAD_ECO57 ;  B5YWD2, COAD_ECO5E ;  B7NPE0, COAD_ECO7I ;
DR   B7N1T5, COAD_ECO81 ;  B7M4B8, COAD_ECO8A ;  C4ZXM6, COAD_ECOBW ;
DR   B1X968, COAD_ECODH ;  A8A696, COAD_ECOHS ;  Q0TBH5, COAD_ECOL5 ;
DR   Q8FC88, COAD_ECOL6 ;  B1IZF9, COAD_ECOLC ;  P0A6I6, COAD_ECOLI ;
DR   B7NET8, COAD_ECOLU ;  B6I3L1, COAD_ECOSE ;  B1LK71, COAD_ECOSM ;
DR   Q1R4V9, COAD_ECOUT ;  C5B9D9, COAD_EDWI9 ;  A4W515, COAD_ENT38 ;
DR   Q831P9, COAD_ENTFA ;  A7MQ98, COAD_ENTS8 ;  Q6DAV2, COAD_ERWCT ;
DR   B2VF71, COAD_ERWT9 ;  B7LVJ5, COAD_ESCF3 ;  C4Z0C3, COAD_EUBE2 ;
DR   C4Z9Y1, COAD_EUBR3 ;  B1YIV1, COAD_EXIS2 ;  C4L5T1, COAD_EXISA ;
DR   B0S155, COAD_FINM2 ;  A5FGN1, COAD_FLAJ1 ;  A6GXD6, COAD_FLAPJ ;
DR   Q0RDM7, COAD_FRAAA ;  B0TYA1, COAD_FRAP2 ;  Q2J6Y5, COAD_FRASC ;
DR   A8L588, COAD_FRASN ;  Q14IN9, COAD_FRAT1 ;  A7ND27, COAD_FRATF ;
DR   Q2A2Q6, COAD_FRATH ;  B2SHB2, COAD_FRATM ;  A0Q5Y0, COAD_FRATN ;
DR   Q0BL95, COAD_FRATO ;  Q5NH87, COAD_FRATT ;  A4IZ18, COAD_FRATW ;
DR   Q8RGX1, COAD_FUSNN ;  B5EB44, COAD_GEOBB ;  Q5L0Z6, COAD_GEOKA ;
DR   Q39UT4, COAD_GEOMG ;  B9M4U3, COAD_GEOSF ;  Q74DS2, COAD_GEOSL ;
DR   C6DZ58, COAD_GEOSM ;  C5D8K3, COAD_GEOSW ;  A4ILY8, COAD_GEOTN ;
DR   A5G4G0, COAD_GEOUR ;  Q7NMB9, COAD_GLOVI ;  A0M4U6, COAD_GRAFK ;
DR   Q7VNN7, COAD_HAEDU ;  Q4QMR6, COAD_HAEI8 ;  A5UE83, COAD_HAEIE ;
DR   A5UHE3, COAD_HAEIG ;  P44805, COAD_HAEIN ;  B8F6N2, COAD_HAEPS ;
DR   Q0I593, COAD_HAES1 ;  B0URI7, COAD_HAES2 ;  Q2SN79, COAD_HAHCH ;
DR   A1WZG0, COAD_HALHL ;  C4K764, COAD_HAMD5 ;  Q17V95, COAD_HELAH ;
DR   Q7VGG0, COAD_HELHP ;  B0TGU9, COAD_HELMI ;  B6JNX3, COAD_HELP2 ;
DR   B5Z994, COAD_HELPG ;  Q1CRB7, COAD_HELPH ;  Q9ZJE4, COAD_HELPJ ;
DR   B2UVM0, COAD_HELPS ;  O26010, COAD_HELPY ;  A9AWY7, COAD_HERA2 ;
DR   A4G927, COAD_HERAR ;  Q5QUN6, COAD_IDILO ;  A6T2S8, COAD_JANMA ;
DR   B5XTG9, COAD_KLEP3 ;  A6TFM5, COAD_KLEP7 ;  Q9XC89, COAD_KLEPN ;
DR   B2GFL8, COAD_KOCRD ;  C5CFP6, COAD_KOSOT ;  Q5FKS7, COAD_LACAC ;
DR   Q03QM5, COAD_LACBA ;  Q039M3, COAD_LACC3 ;  B3WE28, COAD_LACCB ;
DR   B2GBB0, COAD_LACF3 ;  Q042S6, COAD_LACGA ;  A8YUR4, COAD_LACH4 ;
DR   Q74JV6, COAD_LACJO ;  Q9CDQ6, COAD_LACLA ;  A2RNW2, COAD_LACLM ;
DR   Q02VX0, COAD_LACLS ;  Q88VC8, COAD_LACPL ;  A5VJ82, COAD_LACRD ;
DR   B2G6Q2, COAD_LACRJ ;  Q38WQ7, COAD_LACSS ;  Q1MRN8, COAD_LAWIP ;
DR   Q5X7J6, COAD_LEGPA ;  A5IH08, COAD_LEGPC ;  Q5ZY26, COAD_LEGPH ;
DR   Q5WYZ4, COAD_LEGPL ;  Q6AFJ7, COAD_LEIXX ;  B0S9J5, COAD_LEPBA ;
DR   Q04P85, COAD_LEPBJ ;  Q056E9, COAD_LEPBL ;  B0SJR1, COAD_LEPBP ;
DR   Q72M66, COAD_LEPIC ;  Q8EYP6, COAD_LEPIN ;  B1MXS2, COAD_LEUCK ;
DR   Q03VT9, COAD_LEUMM ;  Q929W5, COAD_LISIN ;  C1KX05, COAD_LISMC ;
DR   Q71XW2, COAD_LISMF ;  B8DH77, COAD_LISMH ;  Q8Y5K7, COAD_LISMO ;
DR   A0AKF8, COAD_LISW6 ;  B1HPW8, COAD_LYSSC ;  B9EB42, COAD_MACCJ ;
DR   Q65R52, COAD_MANSM ;  A1U6M5, COAD_MARAV ;  Q11IH7, COAD_MESSB ;
DR   Q8TK70, COAD_METAC ;  Q46A30, COAD_METBF ;  Q60CN9, COAD_METCA ;
DR   Q1H3D2, COAD_METFK ;  B3DYW1, COAD_METI4 ;  Q58436, COAD_METJA ;
DR   Q8TGY4, COAD_METKA ;  Q8PZN4, COAD_METMA ;  B8IK26, COAD_METNO ;
DR   B1LVR4, COAD_METRJ ;  B0UP59, COAD_METS4 ;  B8EIU8, COAD_METSB ;
DR   O27918, COAD_METTH ;  B0JPJ2, COAD_MICAN ;  C5CAE0, COAD_MICLC ;
DR   Q2RHB8, COAD_MOOTA ;  A0QJ93, COAD_MYCA1 ;  B1MDL6, COAD_MYCA9 ;
DR   P0A531, COAD_MYCBO ;  A1KMV9, COAD_MYCBP ;  C1AG80, COAD_MYCBT ;
DR   P45616, COAD_MYCCT ;  A4TE51, COAD_MYCGI ;  O69466, COAD_MYCLE ;
DR   B2HIK6, COAD_MYCMM ;  Q6MTX3, COAD_MYCMS ;  Q73VL1, COAD_MYCPA ;
DR   Q8EUG2, COAD_MYCPE ;  Q98RB3, COAD_MYCPU ;  A0QV16, COAD_MYCS2 ;
DR   A3PXT6, COAD_MYCSJ ;  A1UED2, COAD_MYCSK ;  A5U6X4, COAD_MYCTA ;
DR   P0A530, COAD_MYCTU ;  A0PQ17, COAD_MYCUA ;  A1T732, COAD_MYCVP ;
DR   B2A2L7, COAD_NATTJ ;  B9L9C2, COAD_NAUPA ;  Q5F551, COAD_NEIG1 ;
DR   A9M0K2, COAD_NEIM0 ;  P63816, COAD_NEIMA ;  P63817, COAD_NEIMB ;
DR   A1KW97, COAD_NEIMF ;  Q0ADM4, COAD_NITEC ;  Q820N3, COAD_NITEU ;
DR   Q1QMG7, COAD_NITHX ;  Q2Y5F0, COAD_NITMU ;  Q3SRN1, COAD_NITWN ;
DR   Q5YS03, COAD_NOCFA ;  A1SLV0, COAD_NOCSJ ;  B2J6C6, COAD_NOSP7 ;
DR   Q8YN70, COAD_NOSS1 ;  Q8ER64, COAD_OCEIH ;  A6X0Z2, COAD_OCHA4 ;
DR   Q04EI9, COAD_OENOB ;  B6JFC5, COAD_OLICO ;  B1ZWG7, COAD_OPITP ;
DR   A1BAJ6, COAD_PARDP ;  A7HXM4, COAD_PARL1 ;  Q9CLD4, COAD_PASMU ;
DR   Q8VW75, COAD_PASPI ;  C6DIB6, COAD_PECCP ;  Q03F16, COAD_PEDPA ;
DR   Q3A423, COAD_PELCD ;  Q3B3M9, COAD_PELLD ;  B4SGQ2, COAD_PELPB ;
DR   Q4FLZ4, COAD_PELUB ;  A9BIS4, COAD_PETMO ;  Q7MY37, COAD_PHOLL ;
DR   Q6LVM8, COAD_PHOPR ;  B1XS68, COAD_POLNS ;  A4T072, COAD_POLSQ ;
DR   B2RL67, COAD_PORG3 ;  Q7MX47, COAD_PORGI ;  B4S8K5, COAD_PROA2 ;
DR   Q6A7Q4, COAD_PROAC ;  A3PCX3, COAD_PROM0 ;  A2C247, COAD_PROM1 ;
DR   A8G4U2, COAD_PROM2 ;  A2C9T2, COAD_PROM3 ;  A9BAE9, COAD_PROM4 ;
DR   A2BWL2, COAD_PROM5 ;  Q31AW9, COAD_PROM9 ;  Q7VBZ0, COAD_PROMA ;
DR   B4F0X7, COAD_PROMH ;  Q8RSX4, COAD_PROMI ;  Q7V7L9, COAD_PROMM ;
DR   Q7V1I7, COAD_PROMP ;  A2BR50, COAD_PROMS ;  Q46L10, COAD_PROMT ;
DR   Q15ZV3, COAD_PSEA6 ;  B7V2S6, COAD_PSEA8 ;  Q02U51, COAD_PSEAB ;
DR   Q9I6D1, COAD_PSEAE ;  Q1IGF0, COAD_PSEE4 ;  Q4K4A7, COAD_PSEF5 ;
DR   C3K3N4, COAD_PSEFS ;  Q3IHU4, COAD_PSEHT ;  A4Y022, COAD_PSEMY ;
DR   A5WAF7, COAD_PSEP1 ;  Q3K569, COAD_PSEPF ;  B0KN77, COAD_PSEPG ;
DR   Q88CQ7, COAD_PSEPK ;  B1J2E9, COAD_PSEPW ;  Q88AH3, COAD_PSESM ;
DR   Q4ZM37, COAD_PSEU2 ;  A1SR02, COAD_PSYIN ;  Q9UYT0, COAD_PYRAB ;
DR   Q8ZY96, COAD_PYRAE ;  Q8U1X0, COAD_PYRFU ;  O58358, COAD_PYRHO ;
DR   Q5JHE8, COAD_PYRKO ;  Q1LRQ5, COAD_RALME ;  B2UER1, COAD_RALPJ ;
DR   Q8Y2E6, COAD_RALSO ;  A9WMZ3, COAD_RENSM ;  B3PZQ8, COAD_RHIE6 ;
DR   Q2K8D9, COAD_RHIEC ;  Q1MGM6, COAD_RHIL3 ;  Q98M51, COAD_RHILO ;
DR   B5ZPR5, COAD_RHILW ;  Q92PY8, COAD_RHIME ;  C3MD28, COAD_RHISN ;
DR   Q7UKG6, COAD_RHOBA ;  B6ISP7, COAD_RHOCS ;  C0ZXQ0, COAD_RHOE4 ;
DR   C1B2Q0, COAD_RHOOB ;  Q2IW34, COAD_RHOP2 ;  Q07MY1, COAD_RHOP5 ;
DR   Q6N6L4, COAD_RHOPA ;  Q214P8, COAD_RHOPB ;  Q137B2, COAD_RHOPS ;
DR   B3QIM6, COAD_RHOPT ;  Q2RTK2, COAD_RHORT ;  A3PK50, COAD_RHOS1 ;
DR   Q3J263, COAD_RHOS4 ;  A4WSC5, COAD_RHOS5 ;  Q0S2E4, COAD_RHOSR ;
DR   A7NK79, COAD_ROSCS ;  Q164T8, COAD_ROSDO ;  A5UWI3, COAD_ROSS1 ;
DR   Q1AW92, COAD_RUBXD ;  B5EXD9, COAD_SALA4 ;  A9MKP0, COAD_SALAR ;
DR   Q57IA8, COAD_SALCH ;  B5FM58, COAD_SALDC ;  B5R5F8, COAD_SALEP ;
DR   B5RGF3, COAD_SALG2 ;  B4T9B9, COAD_SALHS ;  B4SXD6, COAD_SALNS ;
DR   Q5PC10, COAD_SALPA ;  A9MVM9, COAD_SALPB ;  C0Q1W7, COAD_SALPC ;
DR   B5BI08, COAD_SALPK ;  B4TZX6, COAD_SALSV ;  Q8Z2H1, COAD_SALTI ;
DR   A4X4F2, COAD_SALTO ;  Q8ZL48, COAD_SALTY ;  Q9X980, COAD_SERMA ;
DR   A8GLE1, COAD_SERP5 ;  B8EDR6, COAD_SHEB2 ;  A3CYP1, COAD_SHEB5 ;
DR   A6WUF6, COAD_SHEB8 ;  A9KWX0, COAD_SHEB9 ;  Q12SS1, COAD_SHEDO ;
DR   Q07W63, COAD_SHEFN ;  B0TMZ9, COAD_SHEHH ;  A3QJB0, COAD_SHELP ;
DR   Q8E8I0, COAD_SHEON ;  A8HA30, COAD_SHEPA ;  A4YCB1, COAD_SHEPC ;
DR   B8CVD4, COAD_SHEPW ;  A0L2N9, COAD_SHESA ;  A8FPF5, COAD_SHESH ;
DR   Q0HDB6, COAD_SHESM ;  Q0HPJ5, COAD_SHESR ;  A1RE18, COAD_SHESW ;
DR   B1KL36, COAD_SHEWM ;  B2TTU8, COAD_SHIB3 ;  Q31UZ2, COAD_SHIBS ;
DR   Q329M3, COAD_SHIDS ;  Q0SYG2, COAD_SHIF8 ;  P0A6I8, COAD_SHIFL ;
DR   Q3YVZ6, COAD_SHISS ;  Q5LRC9, COAD_SILPO ;  Q1GHM4, COAD_SILST ;
DR   Q2NQU5, COAD_SODGM ;  Q1GR20, COAD_SPHAL ;  A5V280, COAD_SPHWW ;
DR   A7X140, COAD_STAA1 ;  A6U0U2, COAD_STAA2 ;  Q2FHV6, COAD_STAA3 ;
DR   Q2FZF5, COAD_STAA8 ;  A5IS11, COAD_STAA9 ;  Q2YXA0, COAD_STAAB ;
DR   Q5HGV9, COAD_STAAC ;  A6QFX8, COAD_STAAE ;  P63818, COAD_STAAM ;
DR   P63819, COAD_STAAN ;  Q6GHW1, COAD_STAAR ;  Q6GA90, COAD_STAAS ;
DR   A8Z1Q8, COAD_STAAT ;  P63820, COAD_STAAW ;  B9DPV4, COAD_STACT ;
DR   Q5HQ42, COAD_STAEQ ;  Q8CSZ5, COAD_STAES ;  Q4L5D8, COAD_STAHJ ;
DR   Q49WP9, COAD_STAS1 ;  Q3K2R6, COAD_STRA1 ;  Q8E6R1, COAD_STRA3 ;
DR   Q8E1A6, COAD_STRA5 ;  Q82JT5, COAD_STRAW ;  Q9ZBR1, COAD_STRCO ;
DR   C0MBZ1, COAD_STRE4 ;  B4U1S8, COAD_STREM ;  A8AVZ4, COAD_STRGC ;
DR   B1VYY6, COAD_STRGG ;  B4SS16, COAD_STRM5 ;  B2FLW4, COAD_STRMK ;
DR   Q8DVH2, COAD_STRMU ;  P63821, COAD_STRP1 ;  Q04IK0, COAD_STRP2 ;
DR   P0DA42, COAD_STRP3 ;  B5E2G0, COAD_STRP4 ;  Q5XAZ0, COAD_STRP6 ;
DR   C1CA14, COAD_STRP7 ;  P63823, COAD_STRP8 ;  Q1JAS0, COAD_STRPB ;
DR   Q1JKX1, COAD_STRPC ;  Q1JFZ7, COAD_STRPD ;  Q1J5R2, COAD_STRPF ;
DR   A2RDJ7, COAD_STRPG ;  B1I8S2, COAD_STRPI ;  B8ZNX4, COAD_STRPJ ;
DR   Q48SJ5, COAD_STRPM ;  Q97NQ2, COAD_STRPN ;  P0DA43, COAD_STRPQ ;
DR   B2IM47, COAD_STRPS ;  B5XMB5, COAD_STRPZ ;  Q8DNE6, COAD_STRR6 ;
DR   A4W3A8, COAD_STRS2 ;  C0MD70, COAD_STRS7 ;  A3CLL0, COAD_STRSV ;
DR   A4VX07, COAD_STRSY ;  B9DUX7, COAD_STRU0 ;  C1CGQ1, COAD_STRZJ ;
DR   C1CMR5, COAD_STRZP ;  C1CTM3, COAD_STRZT ;  Q67PG9, COAD_SYMTH ;
DR   Q2LTS1, COAD_SYNAS ;  Q55235, COAD_SYNE7 ;  Q2JRG2, COAD_SYNJA ;
DR   Q2JJM6, COAD_SYNJB ;  B1XNE8, COAD_SYNP2 ;  Q5N092, COAD_SYNP6 ;
DR   A5GL79, COAD_SYNPW ;  Q7U6T8, COAD_SYNPX ;  A5GT90, COAD_SYNR3 ;
DR   Q0IAF3, COAD_SYNS3 ;  Q3AXV0, COAD_SYNS9 ;  Q3AJW3, COAD_SYNSC ;
DR   Q0AZ31, COAD_SYNWW ;  Q55435, COAD_SYNY3 ;  C5BLM4, COAD_TERTT ;
DR   Q9HIY2, COAD_THEAC ;  Q8DJQ7, COAD_THEEB ;  Q47S81, COAD_THEFY ;
DR   C5A3G3, COAD_THEGJ ;  A8F4E1, COAD_THELT ;  A6LKD2, COAD_THEM4 ;
DR   Q9WZK0, COAD_THEMA ;  B9KAN6, COAD_THENN ;  A5IJ44, COAD_THEP1 ;
DR   B0K9Z1, COAD_THEP3 ;  B0K1X4, COAD_THEPX ;  B9L2B5, COAD_THERP ;
DR   B1L7W5, COAD_THESQ ;  Q72K87, COAD_THET2 ;  Q5SJS9, COAD_THET8 ;
DR   Q8R9U9, COAD_THETN ;  Q97BQ0, COAD_THEVO ;  B5YK79, COAD_THEYD ;
DR   Q31EA3, COAD_THICR ;  Q3SLS2, COAD_THIDA ;  B8GUN6, COAD_THISH ;
DR   C4L7W3, COAD_TOLAT ;  Q73MY1, COAD_TREDE ;  O83307, COAD_TREPA ;
DR   B2S2N1, COAD_TREPS ;  Q115H2, COAD_TRIEI ;  Q83I84, COAD_TROW8 ;
DR   Q83FX9, COAD_TROWT ;  A5CX55, COAD_VESOH ;  A5F408, COAD_VIBC3 ;
DR   Q9KVC4, COAD_VIBCH ;  C3LQI4, COAD_VIBCM ;  Q5E8L9, COAD_VIBF1 ;
DR   B5FFG3, COAD_VIBFM ;  A7MSN5, COAD_VIBHB ;  Q87T80, COAD_VIBPA ;
DR   B7VHL5, COAD_VIBSL ;  Q8DDY6, COAD_VIBVU ;  Q7MPS0, COAD_VIBVY ;
DR   Q8D2R5, COAD_WIGBR ;  Q73HM7, COAD_WOLPM ;  B3CMX3, COAD_WOLPP ;
DR   Q7M9X2, COAD_WOLSU ;  Q5GRI5, COAD_WOLTR ;  C0R2K8, COAD_WOLWR ;
DR   Q8PJK5, COAD_XANAC ;  Q3BS23, COAD_XANC5 ;  Q4UVY5, COAD_XANC8 ;
DR   B0RRP8, COAD_XANCB ;  Q8P857, COAD_XANCP ;  Q2P2V0, COAD_XANOM ;
DR   B2SIL3, COAD_XANOP ;  Q5GZV9, COAD_XANOR ;  B2I7J1, COAD_XYLF2 ;
DR   Q9PEP8, COAD_XYLFA ;  B0U1Z4, COAD_XYLFM ;  Q87EM8, COAD_XYLFT ;
DR   P53332, COAD_YEAST ;  A1JHR9, COAD_YERE8 ;  A7FCT8, COAD_YERP3 ;
DR   Q1C271, COAD_YERPA ;  B2JYN7, COAD_YERPB ;  Q8ZJN9, COAD_YERPE ;
DR   A9R678, COAD_YERPG ;  Q1CD06, COAD_YERPN ;  A4TSD3, COAD_YERPP ;
DR   Q66GD2, COAD_YERPS ;  B1JQW9, COAD_YERPY ;  Q9RME4, COAD_ZYMMO ;
DR   Q13057, COASY_HUMAN;  Q9DBL7, COASY_MOUSE;  Q8MIR4, COASY_PIG  ;
//
ID   2.7.7.4
DE   Sulfate adenylyltransferase.
AN   ATP-sulfurylase.
AN   Sulfate adenylate transferase.
AN   Sulfurylase.
CA   ATP + sulfate = diphosphate + adenylyl sulfate.
CC   -!- The human phosphoadenosine-phosphosulfate synthase (PAPS) system is a
CC       bifunctional enzyme: ATP sulfurylase, which catalyzes the formation
CC       of adenosine 5'-phosphosulfate (APS) from ATP and inorganic sulfate
CC       and the second step is catalyzed by the APS kinase portion of
CC       3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthase, which involves
CC       the formation of PAPS from enzyme bound APS and ATP.
CC   -!- This is in contrast to what is found in bacteria, yeasts, fungi and
CC       plants, where the formation of PAPS is carried out by two individual
CC       polypeptides, EC 2.7.7.4 and EC 2.7.1.25.
DR   Q9LIK9, APS1_ARATH ;  Q43870, APS2_ARATH ;  O23324, APS3_ARATH ;
DR   Q9S7D8, APS4_ARATH ;  Q0A977, CYSD1_ALHEH;  Q1QWX0, CYSD1_CHRSD;
DR   A1U3Y0, CYSD1_MARAV;  A8FXJ5, CYSD1_SHESH;  Q0A653, CYSD2_ALHEH;
DR   Q1QUF8, CYSD2_CHRSD;  A1U490, CYSD2_MARAV;  A8FXM2, CYSD2_SHESH;
DR   Q6FDA0, CYSD_ACIAD ;  B0VSD7, CYSD_ACIBS ;  B0V9N5, CYSD_ACIBY ;
DR   A0KP36, CYSD_AERHH ;  A4SRG9, CYSD_AERS4 ;  B9JB96, CYSD_AGRRK ;
DR   Q7D0L8, CYSD_AGRT5 ;  B9JT86, CYSD_AGRVS ;  B2URN8, CYSD_AKKM8 ;
DR   B6ELP2, CYSD_ALISL ;  A8EWR5, CYSD_ARCB4 ;  C1DQ71, CYSD_AZOVD ;
DR   Q5LES4, CYSD_BACFN ;  Q64VR0, CYSD_BACFR ;  Q8AAQ0, CYSD_BACTN ;
DR   A6KXG8, CYSD_BACV8 ;  Q1LTP5, CYSD_BAUCH ;  A5E8X6, CYSD_BRASB ;
DR   A4YYA7, CYSD_BRASO ;  Q2YP46, CYSD_BRUA2 ;  Q57FI5, CYSD_BRUAB ;
DR   A9M7D7, CYSD_BRUC2 ;  C0RGP5, CYSD_BRUMB ;  Q8YEX2, CYSD_BRUME ;
DR   A5VNC5, CYSD_BRUO2 ;  B0CJ51, CYSD_BRUSI ;  Q8G2W6, CYSD_BRUSU ;
DR   B8D9K2, CYSD_BUCA5 ;  P57499, CYSD_BUCAI ;  B8D7V4, CYSD_BUCAT ;
DR   Q39EM7, CYSD_BURS3 ;  Q9A881, CYSD_CAUCR ;  B0T3J3, CYSD_CAUSK ;
DR   Q7NVN6, CYSD_CHRVO ;  A8ANW6, CYSD_CITK8 ;  Q483A0, CYSD_COLP3 ;
DR   A7ZQJ6, CYSD_ECO24 ;  B7UHH1, CYSD_ECO27 ;  B7MKM6, CYSD_ECO45 ;
DR   B7LEH0, CYSD_ECO55 ;  Q8X7X4, CYSD_ECO57 ;  B5Z3B4, CYSD_ECO5E ;
DR   B7NT96, CYSD_ECO7I ;  B7MZ53, CYSD_ECO81 ;  B7LXG4, CYSD_ECO8A ;
DR   C4ZZQ6, CYSD_ECOBW ;  B1XCS8, CYSD_ECODH ;  A8A3N1, CYSD_ECOHS ;
DR   A1AEU6, CYSD_ECOK1 ;  Q0TEA6, CYSD_ECOL5 ;  Q8FEJ0, CYSD_ECOL6 ;
DR   B1IUS7, CYSD_ECOLC ;  P21156, CYSD_ECOLI ;  B7N6Y2, CYSD_ECOLU ;
DR   B6I6E2, CYSD_ECOSE ;  B1LQ73, CYSD_ECOSM ;  Q1R7T9, CYSD_ECOUT ;
DR   A4WDV7, CYSD_ENT38 ;  A7MJ68, CYSD_ENTS8 ;  Q6D1A5, CYSD_ERWCT ;
DR   B2VG02, CYSD_ERWT9 ;  B7LWK3, CYSD_ESCF3 ;  B5EF56, CYSD_GEOBB ;
DR   B3E8X9, CYSD_GEOLS ;  Q39RP7, CYSD_GEOMG ;  B9M197, CYSD_GEOSF ;
DR   C6E751, CYSD_GEOSM ;  A5G8G3, CYSD_GEOUR ;  Q2SBG0, CYSD_HAHCH ;
DR   A1WZK4, CYSD_HALHL ;  Q0C438, CYSD_HYPNA ;  B5XV29, CYSD_KLEP3 ;
DR   A6TD44, CYSD_KLEP7 ;  A0L6E2, CYSD_MAGSM ;  Q0ALV0, CYSD_MARMM ;
DR   A6VXC5, CYSD_MARMS ;  Q11K42, CYSD_MESSB ;  B7L0Y0, CYSD_METC4 ;
DR   Q604B7, CYSD_METCA ;  A9W4X2, CYSD_METEP ;  B8IRX8, CYSD_METNO ;
DR   B1Z7C1, CYSD_METPB ;  B1LSA1, CYSD_METRJ ;  B0U8Y5, CYSD_METS4 ;
DR   P65671, CYSD_MYCBO ;  A1KI72, CYSD_MYCBP ;  A4T8Q2, CYSD_MYCGI ;
DR   A3Q3I2, CYSD_MYCSJ ;  A1UK27, CYSD_MYCSK ;  Q1B510, CYSD_MYCSS ;
DR   A5U1Y3, CYSD_MYCTA ;  P65670, CYSD_MYCTU ;  A1TDE9, CYSD_MYCVP ;
DR   Q1D9W6, CYSD_MYXXD ;  Q5YUA1, CYSD_NOCFA ;  A6WVC7, CYSD_OCHA4 ;
DR   A6LA51, CYSD_PARD8 ;  C6DDH0, CYSD_PECCP ;  Q3A3P5, CYSD_PELCD ;
DR   Q7N8L1, CYSD_PHOLL ;  Q6LM68, CYSD_PHOPR ;  B4F231, CYSD_PROMH ;
DR   A4SDU0, CYSD_PROVI ;  Q48ED3, CYSD_PSE14 ;  Q15VB5, CYSD_PSEA6 ;
DR   A6VBB6, CYSD_PSEA7 ;  B7UZY2, CYSD_PSEA8 ;  Q02GZ8, CYSD_PSEAB ;
DR   O50273, CYSD_PSEAE ;  Q1I585, CYSD_PSEE4 ;  Q4KI67, CYSD_PSEF5 ;
DR   C3KDP1, CYSD_PSEFS ;  Q3ILR0, CYSD_PSEHT ;  A4XQP2, CYSD_PSEMY ;
DR   A5W8T2, CYSD_PSEP1 ;  Q3KHY6, CYSD_PSEPF ;  B0KGN7, CYSD_PSEPG ;
DR   Q88NA9, CYSD_PSEPK ;  B1J166, CYSD_PSEPW ;  Q87WW0, CYSD_PSESM ;
DR   Q4ZNW4, CYSD_PSEU2 ;  A4VIE6, CYSD_PSEU5 ;  A1ST25, CYSD_PSYIN ;
DR   B3PTD3, CYSD_RHIE6 ;  Q2KB48, CYSD_RHIEC ;  Q1MJV3, CYSD_RHIL3 ;
DR   Q985Q5, CYSD_RHILO ;  B5ZUF6, CYSD_RHILW ;  P56892, CYSD_RHIME ;
DR   O33580, CYSD_RHITR ;  Q07UU1, CYSD_RHOP5 ;  Q21D94, CYSD_RHOPB ;
DR   Q2RS06, CYSD_RHORT ;  Q21IS4, CYSD_SACD2 ;  B5F416, CYSD_SALA4 ;
DR   A9MF23, CYSD_SALAR ;  Q57KI9, CYSD_SALCH ;  B5FTT0, CYSD_SALDC ;
DR   B5QW23, CYSD_SALEP ;  B5RDQ8, CYSD_SALG2 ;  B4TFX2, CYSD_SALHS ;
DR   B4T462, CYSD_SALNS ;  Q5PEH1, CYSD_SALPA ;  A9N2D9, CYSD_SALPB ;
DR   B5BEY9, CYSD_SALPK ;  B4TTW6, CYSD_SALSV ;  P65673, CYSD_SALTI ;
DR   P65672, CYSD_SALTY ;  A8G9Y4, CYSD_SERP5 ;  A1S9N7, CYSD_SHEAM ;
DR   B8EE60, CYSD_SHEB2 ;  A3D822, CYSD_SHEB5 ;  A6WJU3, CYSD_SHEB8 ;
DR   A9L389, CYSD_SHEB9 ;  Q12QM9, CYSD_SHEDO ;  Q07Y91, CYSD_SHEFN ;
DR   B0TTD5, CYSD_SHEHH ;  A3QCU1, CYSD_SHELP ;  Q8EB09, CYSD_SHEON ;
DR   A8H0A3, CYSD_SHEPA ;  A4Y9X3, CYSD_SHEPC ;  B8CSV0, CYSD_SHEPW ;
DR   A0KTI2, CYSD_SHESA ;  Q0HFM4, CYSD_SHESM ;  Q0HYA6, CYSD_SHESR ;
DR   A1RGF7, CYSD_SHESW ;  B1KMH3, CYSD_SHEWM ;  B2TZH9, CYSD_SHIB3 ;
DR   Q31XB4, CYSD_SHIBS ;  Q32CH8, CYSD_SHIDS ;  Q0T1I3, CYSD_SHIF8 ;
DR   P59740, CYSD_SHIFL ;  Q3YYB0, CYSD_SHISS ;  Q2NVM9, CYSD_SODGM ;
DR   Q30U93, CYSD_SULDN ;  A6QB13, CYSD_SULNB ;  A5F579, CYSD_VIBC3 ;
DR   Q9KP19, CYSD_VIBCH ;  C3LRM2, CYSD_VIBCM ;  Q5E831, CYSD_VIBF1 ;
DR   B5FGJ8, CYSD_VIBFM ;  A7MWG4, CYSD_VIBHB ;  Q87SY0, CYSD_VIBPA ;
DR   B7VKY3, CYSD_VIBSL ;  Q8DE72, CYSD_VIBVU ;  Q7MPF3, CYSD_VIBVY ;
DR   Q8PHD0, CYSD_XANAC ;  Q3BPY6, CYSD_XANC5 ;  Q4UY06, CYSD_XANC8 ;
DR   B0RPG8, CYSD_XANCB ;  Q8P610, CYSD_XANCP ;  Q2P0H4, CYSD_XANOM ;
DR   B2SI03, CYSD_XANOP ;  Q9PD79, CYSD_XYLFA ;  Q87DG8, CYSD_XYLFT ;
DR   A1JJS9, CYSD_YERE8 ;  A7FLY3, CYSD_YERP3 ;  Q1C483, CYSD_YERPA ;
DR   B2K572, CYSD_YERPB ;  Q8ZBP1, CYSD_YERPE ;  A9R1C3, CYSD_YERPG ;
DR   Q1CLS1, CYSD_YERPN ;  A4TPZ2, CYSD_YERPP ;  Q66EC8, CYSD_YERPS ;
DR   B1JJG3, CYSD_YERPY ;  Q5NRM5, CYSD_ZYMMO ;  Q10600, CYSNC_MYCTU;
DR   O50274, CYSNC_PSEAE;  Q7UMW2, CYSNC_RHOBA;  Q9PD78, CYSNC_XYLFA;
DR   Q87DG7, CYSNC_XYLFT;  A0KP35, CYSN_AERHH ;  A4SRG8, CYSN_AERS4 ;
DR   B9JB95, CYSN_AGRRK ;  Q8UH69, CYSN_AGRT5 ;  B6ELP3, CYSN_ALISL ;
DR   B4RTW4, CYSN_ALTMD ;  A8EWR6, CYSN_ARCB4 ;  Q5LES3, CYSN_BACFN ;
DR   Q64VQ9, CYSN_BACFR ;  Q8AAP9, CYSN_BACTN ;  B8D9K1, CYSN_BUCA5 ;
DR   P57498, CYSN_BUCAI ;  B8D7V3, CYSN_BUCAT ;  B3PII1, CYSN_CELJU ;
DR   Q1QUF9, CYSN_CHRSD ;  Q7NVN5, CYSN_CHRVO ;  A8ANW5, CYSN_CITK8 ;
DR   Q482Z9, CYSN_COLP3 ;  A7ZQJ5, CYSN_ECO24 ;  B7UHH0, CYSN_ECO27 ;
DR   B7MKM5, CYSN_ECO45 ;  B7LEG9, CYSN_ECO55 ;  Q8X7X7, CYSN_ECO57 ;
DR   B5Z3B3, CYSN_ECO5E ;  B7NT95, CYSN_ECO7I ;  B7MZ52, CYSN_ECO81 ;
DR   B7LXG3, CYSN_ECO8A ;  C4ZZQ5, CYSN_ECOBW ;  B1XCS7, CYSN_ECODH ;
DR   A8A3N0, CYSN_ECOHS ;  A1AEU5, CYSN_ECOK1 ;  Q0TEA7, CYSN_ECOL5 ;
DR   Q8FEJ1, CYSN_ECOL6 ;  B1IUS8, CYSN_ECOLC ;  P23845, CYSN_ECOLI ;
DR   B7N6Y1, CYSN_ECOLU ;  B6I6E1, CYSN_ECOSE ;  B1LQ72, CYSN_ECOSM ;
DR   Q1R7U0, CYSN_ECOUT ;  A7MJ69, CYSN_ENTS8 ;  B2VG01, CYSN_ERWT9 ;
DR   B7LWK4, CYSN_ESCF3 ;  Q14HG2, CYSN_FRAT1 ;  A0Q6F0, CYSN_FRATN ;
DR   Q5NG10, CYSN_FRATT ;  A4IXZ5, CYSN_FRATW ;  C1D890, CYSN_LARHH ;
DR   B7L0X9, CYSN_METC4 ;  A9W4X1, CYSN_METEP ;  B1Z7C0, CYSN_METPB ;
DR   Q7N8L0, CYSN_PHOLL ;  Q6LM69, CYSN_PHOPR ;  Q15VB8, CYSN_PSEA6 ;
DR   A1ST27, CYSN_PSYIN ;  P56893, CYSN_RHIME ;  O33581, CYSN_RHITR ;
DR   Q21IS6, CYSN_SACD2 ;  B5F415, CYSN_SALA4 ;  A9MF24, CYSN_SALAR ;
DR   Q57KJ0, CYSN_SALCH ;  B5FTS9, CYSN_SALDC ;  B5QW22, CYSN_SALEP ;
DR   B5RDQ7, CYSN_SALG2 ;  B4TFX1, CYSN_SALHS ;  B4T461, CYSN_SALNS ;
DR   Q5PEH2, CYSN_SALPA ;  A9N2D8, CYSN_SALPB ;  C0PXB1, CYSN_SALPC ;
DR   B5BEY8, CYSN_SALPK ;  B4TTW5, CYSN_SALSV ;  Q8Z470, CYSN_SALTI ;
DR   Q8ZMF5, CYSN_SALTY ;  Q8EB10, CYSN_SHEON ;  B1KMH4, CYSN_SHEWM ;
DR   B2TZI0, CYSN_SHIB3 ;  Q31XB3, CYSN_SHIBS ;  Q32CH9, CYSN_SHIDS ;
DR   Q0T1I2, CYSN_SHIF8 ;  Q83JX8, CYSN_SHIFL ;  Q3YYB1, CYSN_SHISS ;
DR   Q2NVM8, CYSN_SODGM ;  A6QB12, CYSN_SULNB ;  C5BSJ5, CYSN_TERTT ;
DR   C4LAG3, CYSN_TOLAT ;  A5F578, CYSN_VIBC3 ;  Q9KP20, CYSN_VIBCH ;
DR   C3LRM1, CYSN_VIBCM ;  Q5E830, CYSN_VIBF1 ;  B5FGJ9, CYSN_VIBFM ;
DR   A7MWE9, CYSN_VIBHB ;  Q87SX9, CYSN_VIBPA ;  B7VKY2, CYSN_VIBSL ;
DR   Q8DE73, CYSN_VIBVU ;  Q7MPF2, CYSN_VIBVY ;  A1JJT0, CYSN_YERE8 ;
DR   A7FLY2, CYSN_YERP3 ;  Q8ZBP2, CYSN_YERPE ;  Q66EC7, CYSN_YERPS ;
DR   Q74ZF6, MET3_ASHGO ;  A1CJC1, MET3_ASPCL ;  Q4WWN8, MET3_ASPFU ;
DR   Q8NJN1, MET3_ASPNG ;  Q8NK83, MET3_ASPOR ;  P56862, MET3_ASPTE ;
DR   Q0CC19, MET3_ASPTN ;  Q9Y872, MET3_CANAL ;  Q6FXQ8, MET3_CANGA ;
DR   Q2H454, MET3_CHAGB ;  Q1EAF9, MET3_COCIM ;  P0CN05, MET3_CRYNB ;
DR   P0CN04, MET3_CRYNJ ;  Q8TG24, MET3_CRYNV ;  Q6BSU5, MET3_DEBHA ;
DR   Q12555, MET3_EMENI ;  Q4I1N3, MET3_GIBZE ;  Q6CNU6, MET3_KLULA ;
DR   Q8J0I4, MET3_MUCCI ;  A1D858, MET3_NEOFI ;  Q7SE75, MET3_NEUCR ;
DR   Q12650, MET3_PENCH ;  Q0V6P9, MET3_PHANO ;  P78937, MET3_SCHPO ;
DR   Q4P460, MET3_USTMA ;  Q6CFD2, MET3_YARLI ;  P08536, MET3_YEAST ;
DR   Q9X5U0, MMCV_STRLA ;  P28603, NODP_AZOBR ;  P13441, NODP_RHIME ;
DR   P72338, NODP_RHIS3 ;  O07308, NODP_RHISB ;  P52995, NODP_RHITR ;
DR   P28604, NODQ_AZOBR ;  P13442, NODQ_RHIME ;  P72339, NODQ_RHIS3 ;
DR   O07309, NODQ_RHISB ;  P52978, NODQ_RHITR ;  O54820, PAPS1_CAVPO;
DR   O43252, PAPS1_HUMAN;  Q60967, PAPS1_MOUSE;  O95340, PAPS2_HUMAN;
DR   O88428, PAPS2_MOUSE;  Q27128, PAPSS_URECA;  O34764, SAT1_BACSU ;
DR   O06736, SAT2_BACSU ;  A9ENT2, SATC1_SORC5;  A9G7W0, SATC2_SORC5;
DR   O67174, SATC_AQUAE ;  B0BZ94, SAT_ACAM1  ;  Q9YCR4, SAT_AERPE  ;
DR   Q0VRM0, SAT_ALCBS  ;  O66036, SAT_ALLVD  ;  Q3MAI6, SAT_ANAVT  ;
DR   O28606, SAT_ARCFU  ;  A7Z4H9, SAT_BACA2  ;  C3P517, SAT_BACAA  ;
DR   C3L9N5, SAT_BACAC  ;  A0RBN3, SAT_BACAH  ;  Q81T48, SAT_BACAN  ;
DR   B7JGQ4, SAT_BACC0  ;  Q73B75, SAT_BACC1  ;  B7INB5, SAT_BACC2  ;
DR   C1EMR9, SAT_BACC3  ;  B7HHH7, SAT_BACC4  ;  B7HKE6, SAT_BACC7  ;
DR   A7GMW1, SAT_BACCN  ;  B9IV12, SAT_BACCQ  ;  Q81FZ0, SAT_BACCR  ;
DR   Q63DV8, SAT_BACCZ  ;  Q6HLD3, SAT_BACHK  ;  Q65JT9, SAT_BACLD  ;
DR   A8FD24, SAT_BACP2  ;  Q5WKF4, SAT_BACSK  ;  A9VLJ0, SAT_BACWK  ;
DR   Q3A8R0, SAT_CARHZ  ;  A0RYU6, SAT_CENSY  ;  A9WFJ2, SAT_CHLAA  ;
DR   Q3AQ83, SAT_CHLCH  ;  B3ELG8, SAT_CHLPB  ;  B9LKB9, SAT_CHLSY  ;
DR   Q8KE30, SAT_CHLTE  ;  B7JVS6, SAT_CYAP8  ;  C1CVW9, SAT_DEIDV  ;
DR   Q1IYH9, SAT_DEIGD  ;  P56864, SAT_DEIRA  ;  B8FB52, SAT_DESAA  ;
DR   B1I3M7, SAT_DESAP  ;  B8J4A8, SAT_DESDA  ;  A4J272, SAT_DESRM  ;
DR   O76156, SAT_ENTHI  ;  Q5L2Y0, SAT_GEOKA  ;  C5D5A6, SAT_GEOSW  ;
DR   A4IKB5, SAT_GEOTN  ;  Q7NLN7, SAT_GLOVI  ;  B8D0S5, SAT_HALOH  ;
DR   A2BMW0, SAT_HYPBU  ;  A8AB48, SAT_IGNH4  ;  Q88X61, SAT_LACPL  ;
DR   B1HXC8, SAT_LYSSC  ;  B0JW81, SAT_MICAN  ;  A9A541, SAT_NITMS  ;
DR   B2J5M3, SAT_NOSP7  ;  Q8EQN5, SAT_OCEIH  ;  B4SAM9, SAT_PELPB  ;
DR   A5D5R7, SAT_PELTS  ;  C0QSU0, SAT_PERMH  ;  A9BFU2, SAT_PETMO  ;
DR   P84547, SAT_POPEU  ;  Q60FC6, SAT_PORYE  ;  Q4FST7, SAT_PSYA2  ;
DR   Q1QAY1, SAT_PSYCK  ;  A5WEH0, SAT_PSYWF  ;  P56863, SAT_PYRAB  ;
DR   Q54506, SAT_RIFPS  ;  Q1AXE5, SAT_RUBXD  ;  A1AVC7, SAT_RUTMC  ;
DR   B9DLL5, SAT_STACT  ;  Q5HL01, SAT_STAEQ  ;  Q8CR03, SAT_STAES  ;
DR   Q4L9E7, SAT_STAHJ  ;  A3DLD9, SAT_STAMF  ;  Q49UM4, SAT_STAS1  ;
DR   Q67QB5, SAT_SYMTH  ;  Q31RJ2, SAT_SYNE7  ;  A0LH38, SAT_SYNFM  ;
DR   Q2JU97, SAT_SYNJA  ;  B1XLP7, SAT_SYNP2  ;  Q5N2R3, SAT_SYNP6  ;
DR   P74241, SAT_SYNY3  ;  B6YUW9, SAT_THEON  ;  Q3SEZ6, SAT_THIDA  ;
DR   Q111K4, SAT_TRIEI  ;  A5CXS6, SAT_VESOH  ;
//
ID   2.7.7.5
DE   Sulfate adenylyltransferase (ADP).
AN   Adenosine diphosphate sulfurylase.
AN   ADP-sulfurylase.
CA   ADP + sulfate = phosphate + adenylyl sulfate.
DR   P16550, APA1_YEAST ;
//
ID   2.7.7.6
DE   DNA-directed RNA polymerase.
AN   DNA-dependent RNA polymerase.
AN   RNA nucleotidyltransferase (DNA-directed).
AN   RNA polymerase I.
AN   RNA polymerase II.
AN   RNA polymerase III.
CA   Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
CC   -!- Catalyzes DNA-template-directed extension of the 3'-end of an RNA
CC       strand by one nucleotide at a time.
CC   -!- Can initiate a chain de novo.
CC   -!- In eukaryotes three forms of the enzyme have been distinguished on
CC       the basis of sensitivity of alpha-amanitin, and the type of RNA
CC       synthesized.
CC   -!- See also EC 2.7.7.19 and EC 2.7.7.48.
PR   PROSITE; PDOC00106;
PR   PROSITE; PDOC00410;
PR   PROSITE; PDOC00411;
PR   PROSITE; PDOC00790;
PR   PROSITE; PDOC00854;
PR   PROSITE; PDOC00855;
PR   PROSITE; PDOC00856;
PR   PROSITE; PDOC00889;
PR   PROSITE; PDOC00896;
DR   Q91FI1, 343L_IIV6  ;  Q9LQ02, NRPD1_ARATH;  Q5D869, NRPE1_ARATH;
DR   Q9J5A4, RP07_FOWPN ;  Q98229, RP07_MCV1  ;  Q9Q8P6, RP07_MYXVL ;
DR   Q9Q921, RP07_RFVKA ;  P68314, RP07_VACCA ;  P68315, RP07_VACCC ;
DR   P68316, RP07_VACCT ;  P68317, RP07_VACCW ;  Q07047, RP07_VAR67 ;
DR   Q9DHQ8, RP07_YLDV  ;  Q8V2N1, RP132_CAMPM;  Q775Q3, RP132_CAMPS;
DR   P17474, RP132_CWPXB;  Q80DV1, RP132_CWPXG;  Q8JL90, RP132_ECTVM;
DR   Q9J544, RP132_FOWPN;  Q8V4V3, RP132_MONPV;  Q6RZF8, RP132_RABPU;
DR   P16716, RP132_SHEVK;  O57230, RP132_VACCA;  P68694, RP132_VACCC;
DR   Q9JF79, RP132_VACCT;  Q76ZP7, RP132_VACCW;  P33811, RP132_VAR67;
DR   Q9J593, RP147_FOWPN;  O57204, RP147_VACCA;  P20504, RP147_VACCC;
DR   P07392, RP147_VACCW;  P33053, RP147_VAR67;  P21967, RP18_FOWPN ;
DR   Q76ZS0, RP18_VACCA ;  P21034, RP18_VACCC ;  P04310, RP18_VACCW ;
DR   P33058, RP18_VAR67 ;  Q05569, RP19_FOWPN ;  Q76ZQ8, RP19_VACCA ;
DR   P68610, RP19_VACCC ;  P68611, RP19_VACCW ;  P33813, RP19_VAR67 ;
DR   Q85280, RP22_FOWPN ;  P68546, RP22_MYXVL ;  P68547, RP22_MYXVU ;
DR   P68608, RP22_VACCC ;  P68609, RP22_VACCW ;  P33054, RP22_VAR67 ;
DR   P21082, RP30_VACCC ;  P21603, RP30_VACCW ;  P33796, RP30_VAR67 ;
DR   Q9J540, RP35_FOWPN ;  Q6RZF4, RP35_RABPU ;  P19749, RP35_SHEVK ;
DR   O57233, RP35_VACCA ;  P21087, RP35_VACCC ;  Q77TH6, RP35_VACCT ;
DR   P24757, RP35_VACCW ;  P33812, RP35_VAR67 ;  Q86H36, RPA1_DICDI ;
DR   P91875, RPA1_DROME ;  P28363, RPA1_EUPOC ;  O95602, RPA1_HUMAN ;
DR   O35134, RPA1_MOUSE ;  O54889, RPA1_RAT   ;  P15398, RPA1_SCHPO ;
DR   P16355, RPA1_TRYBB ;  P10964, RPA1_YEAST ;  Q75DS1, RPA2_ASHGO ;
DR   Q54BM1, RPA2_DICDI ;  P20028, RPA2_DROME ;  P28365, RPA2_EUPOC ;
DR   Q9H9Y6, RPA2_HUMAN ;  P70700, RPA2_MOUSE ;  O74633, RPA2_NEUCR ;
DR   Q5REE8, RPA2_PONAB ;  O54888, RPA2_RAT   ;  Q9P7X8, RPA2_SCHPO ;
DR   P22138, RPA2_YEAST ;  Q06FN2, RPAL1_PELHO;  Q06FN4, RPAL2_PELHO;
DR   Q06FN6, RPAL3_PELHO;  P17546, RPB1A_TRYBB;  P17545, RPB1B_TRYBB;
DR   P18616, RPB1_ARATH ;  P42486, RPB1_ASFB7 ;  P0C989, RPB1_ASFK5 ;
DR   Q65215, RPB1_ASFM2 ;  P0C987, RPB1_ASFP4 ;  P0C988, RPB1_ASFWA ;
DR   Q75A34, RPB1_ASHGO ;  P35074, RPB1_CAEBR ;  P16356, RPB1_CAEEL ;
DR   P11414, RPB1_CRIGR ;  P35084, RPB1_DICDI ;  P04052, RPB1_DROME ;
DR   Q8SSC4, RPB1_ENCCU ;  P28364, RPB1_EUPOC ;  Q6GZW7, RPB1_FRG3G ;
DR   P24928, RPB1_HUMAN ;  Q196X0, RPB1_IIV3  ;  O55766, RPB1_IIV6  ;
DR   P08775, RPB1_MOUSE ;  A5DCV3, RPB1_PICGU ;  P14248, RPB1_PLAFD ;
DR   P36594, RPB1_SCHPO ;  P04050, RPB1_YEAST ;  P38420, RPB2_ARATH ;
DR   P42487, RPB2_ASFB7 ;  P0C8K2, RPB2_ASFK5 ;  P0C8K3, RPB2_ASFM2 ;
DR   P0C8K4, RPB2_ASFP4 ;  P0C8K5, RPB2_ASFWA ;  Q753Q4, RPB2_ASHGO ;
DR   Q10578, RPB2_CAEEL ;  Q6FLD5, RPB2_CANGA ;  Q54J75, RPB2_DICDI ;
DR   P08266, RPB2_DROME ;  Q8SR75, RPB2_ENCCU ;  Q6GZR3, RPB2_FRG3G ;
DR   P30876, RPB2_HUMAN ;  Q197F1, RPB2_IIV3  ;  Q91F97, RPB2_IIV6  ;
DR   Q8CFI7, RPB2_MOUSE ;  A5DHT2, RPB2_PICGU ;  Q02061, RPB2_SCHPO ;
DR   Q42877, RPB2_SOLLC ;  P08518, RPB2_YEAST ;  Q9VEA5, RPB4_DROME ;
DR   Q8HUG9, RPC1A_CHLRE;  A4IF62, RPC1_BOVIN ;  Q5ZL98, RPC1_CHICK ;
DR   Q6BI69, RPC1_DEBHA ;  Q86AQ5, RPC1_DICDI ;  P25202, RPC1_GIAIN ;
DR   O14802, RPC1_HUMAN ;  P27625, RPC1_PLAFA ;  O94666, RPC1_SCHPO ;
DR   P08968, RPC1_TRYBB ;  P04051, RPC1_YEAST ;  Q8HUH0, RPC2B_CHLRE;
DR   Q54IZ9, RPC2_DICDI ;  P25167, RPC2_DROME ;  Q9NW08, RPC2_HUMAN ;
DR   P59470, RPC2_MOUSE ;  Q10233, RPC2_SCHPO ;  P22276, RPC2_YEAST ;
DR   Q9LK40, RPD2A_ARATH;  Q9LV32, RPD2B_ARATH;  Q8L6J4, RPO1A_TOBAC;
DR   Q8L6J5, RPO1B_TOBAC;  Q7T6X5, RPO1_MIMIV ;  Q8L6J2, RPO2A_TOBAC;
DR   Q8L6J3, RPO2B_TOBAC;  Q7T6X7, RPO2_MIMIV ;  P69243, RPO3A_TOBAC;
DR   Q8L6J1, RPO3B_TOBAC;  Q9J5C0, RPO5_FOWPN ;  Q5UPX7, RPO5_MIMIV ;
DR   O57187, RPO5_VACCA ;  Q08399, RPO6_ASFM2 ;  Q5UQ32, RPO6_MIMIV ;
DR   Q14J95, RPOA1_FRAT1;  A7N9U9, RPOA1_FRATF;  Q2A5E5, RPOA1_FRATH;
DR   A0Q4K8, RPOA1_FRATN;  Q0BNQ3, RPOA1_FRATO;  Q5NHU3, RPOA1_FRATT;
DR   A4IZQ9, RPOA1_FRATW;  P15349, RPOA1_HALMO;  B0R8D4, RPOA1_HALS3;
DR   P0CX02, RPOA1_HALSA;  Q58445, RPOA1_METJA;  O27125, RPOA1_METTH;
DR   P09846, RPOA1_METTW;  P41556, RPOA1_METVS;  A1SXW8, RPOA1_PSYIN;
DR   P60313, RPOA1_STRAW;  P11512, RPOA1_SULAC;  Q980R2, RPOA1_SULSO;
DR   Q03585, RPOA1_THEAC;  P31813, RPOA1_THECE;  Q9YAU2, RPOA2_AERPE;
DR   O28390, RPOA2_ARCFU;  Q14GG5, RPOA2_FRAT1;  A7NAX2, RPOA2_FRATF;
DR   Q2A4H7, RPOA2_FRATH;  A0Q7R6, RPOA2_FRATN;  Q0BMV6, RPOA2_FRATO;
DR   Q5NF12, RPOA2_FRATT;  A4IWR6, RPOA2_FRATW;  Q5UZR5, RPOA2_HALMA;
DR   P15353, RPOA2_HALMO;  B0R8D3, RPOA2_HALS3;  P0CX07, RPOA2_HALSA;
DR   A6UV49, RPOA2_META3;  Q8TRB8, RPOA2_METAC;  Q58446, RPOA2_METJA;
DR   A4FWF5, RPOA2_METM5;  A9A9U9, RPOA2_METM6;  A6VGV0, RPOA2_METM7;
DR   Q8PUR2, RPOA2_METMA;  Q6LXI7, RPOA2_METMP;  A4YCR0, RPOA2_METS5;
DR   O27126, RPOA2_METTH;  P09847, RPOA2_METTW;  P14247, RPOA2_METVS;
DR   A1T0B7, RPOA2_PSYIN;  Q9V113, RPOA2_PYRAB;  Q8ZYQ7, RPOA2_PYRAE;
DR   Q8U0M5, RPOA2_PYRFU;  O93777, RPOA2_PYRHO;  Q5JE34, RPOA2_PYRKO;
DR   Q82QR5, RPOA2_STRAW;  P11514, RPOA2_SULAC;  C3MZM9, RPOA2_SULIA;
DR   C4KIV9, RPOA2_SULIK;  C3MRK4, RPOA2_SULIL;  C3MYA0, RPOA2_SULIM;
DR   C3NFS2, RPOA2_SULIN;  C3N7Q1, RPOA2_SULIY;  P58192, RPOA2_SULSO;
DR   Q976A6, RPOA2_SULTO;  Q03586, RPOA2_THEAC;  P29158, RPOA2_THECE;
DR   C5A207, RPOA2_THEGJ;  B6YT17, RPOA2_THEON;  Q979F5, RPOA2_THEVO;
DR   A1TJU2, RPOA_ACIAC ;  Q6F7T7, RPOA_ACIAD ;  B7GW27, RPOA_ACIB3 ;
DR   B7IA14, RPOA_ACIB5 ;  B2HZ83, RPOA_ACIBC ;  Q1IS93, RPOA_ACIBL ;
DR   B0VQU3, RPOA_ACIBS ;  A3M959, RPOA_ACIBT ;  B0V6U7, RPOA_ACIBY ;
DR   A0LRP8, RPOA_ACIC1 ;  A5FZU1, RPOA_ACICJ ;  B9MBW2, RPOA_ACIET ;
DR   A1W333, RPOA_ACISJ ;  Q3V502, RPOA_ACOCL ;  Q5QA74, RPOA_ACOGR ;
DR   A3N382, RPOA_ACTP2 ;  A6VLL3, RPOA_ACTSZ ;  Q85FJ1, RPOA_ADICA ;
DR   Q7GED9, RPOA_AEGCM ;  P92892, RPOA_AEGSP ;  P92429, RPOA_AEGTA ;
DR   Q8MAJ0, RPOA_AEGUN ;  A0KF45, RPOA_AERHH ;  A4SSY1, RPOA_AERS4 ;
DR   A4QJE7, RPOA_AETCO ;  A4QJN1, RPOA_AETGR ;  P92209, RPOA_AGRCR ;
DR   B9JDV2, RPOA_AGRRK ;  A1EA40, RPOA_AGRST ;  P0A4E3, RPOA_AGRT5 ;
DR   B9JVR1, RPOA_AGRVS ;  Q0VSH8, RPOA_ALCBS ;  Q0ABF0, RPOA_ALHEH ;
DR   B6EPU9, RPOA_ALISL ;  A6TWF3, RPOA_ALKMQ ;  A8MLG9, RPOA_ALKOO ;
DR   P60314, RPOA_AMBTC ;  B8J887, RPOA_ANAD2 ;  Q2IJ57, RPOA_ANADE ;
DR   A7HBP5, RPOA_ANADF ;  Q5PA81, RPOA_ANAMM ;  Q2GL36, RPOA_ANAPZ ;
DR   B4UBC6, RPOA_ANASK ;  B9MKF3, RPOA_ANATD ;  Q3MF97, RPOA_ANAVT ;
DR   A2T365, RPOA_ANGEV ;  Q85A01, RPOA_ANTFO ;  O66483, RPOA_AQUAE ;
DR   A4QK50, RPOA_ARAHI ;  P56762, RPOA_ARATH ;  A8ETK6, RPOA_ARCB4 ;
DR   Q5P307, RPOA_AROAE ;  A1R8R5, RPOA_ARTAT ;  B8HCX4, RPOA_ARTCA ;
DR   A0JZ49, RPOA_ARTS2 ;  P34778, RPOA_ASTLO ;  Q8S8V9, RPOA_ATRBE ;
DR   P93993, RPOA_AUSVE ;  Q2NIY1, RPOA_AYWBP ;  A8IAN5, RPOA_AZOC5 ;
DR   A1KB01, RPOA_AZOSB ;  A7Z0R5, RPOA_BACA2 ;  A0R8K6, RPOA_BACAH ;
DR   Q81VQ4, RPOA_BACAN ;  Q73F69, RPOA_BACC1 ;  A7GK47, RPOA_BACCN ;
DR   Q81J18, RPOA_BACCR ;  Q63H64, RPOA_BACCZ ;  Q5L8D6, RPOA_BACFN ;
DR   Q64NN5, RPOA_BACFR ;  O50634, RPOA_BACHD ;  Q6HPN2, RPOA_BACHK ;
DR   Q65P79, RPOA_BACLD ;  A8F9B2, RPOA_BACP2 ;  Q5WLN5, RPOA_BACSK ;
DR   P20429, RPOA_BACSU ;  Q8A4A2, RPOA_BACTN ;  A6KYH0, RPOA_BACV8 ;
DR   A1USR8, RPOA_BARBK ;  Q9FDC7, RPOA_BARHE ;  Q6FZE6, RPOA_BARQU ;
DR   A9IVZ5, RPOA_BART1 ;  A4QKD7, RPOA_BARVE ;  Q1LTB3, RPOA_BAUCH ;
DR   Q6MJ36, RPOA_BDEBA ;  B2IF96, RPOA_BEII9 ;  C5C0G1, RPOA_BEUC1 ;
DR   A1A095, RPOA_BIFAA ;  Q8G3Z3, RPOA_BIFLO ;  Q06J39, RPOA_BIGNA ;
DR   Q7VQC3, RPOA_BLOFL ;  Q493I4, RPOA_BLOPB ;  Q2L238, RPOA_BORA1 ;
DR   Q0SN05, RPOA_BORAP ;  P0A4E6, RPOA_BORBR ;  O51455, RPOA_BORBU ;
DR   Q661B8, RPOA_BORGA ;  P0A4E7, RPOA_BORPA ;  A9IHR6, RPOA_BORPD ;
DR   P0A4E5, RPOA_BORPE ;  Q89JA7, RPOA_BRAJA ;  A5ELK3, RPOA_BRASB ;
DR   A4YSL6, RPOA_BRASO ;  C0ZIK7, RPOA_BREBN ;  P92220, RPOA_BROIN ;
DR   B2S655, RPOA_BRUA1 ;  Q2YRU0, RPOA_BRUA2 ;  Q57CT2, RPOA_BRUAB ;
DR   A9M5M5, RPOA_BRUC2 ;  C0RJH6, RPOA_BRUMB ;  Q8YHL6, RPOA_BRUME ;
DR   A5VQY2, RPOA_BRUO2 ;  B0CH07, RPOA_BRUSI ;  Q8G094, RPOA_BRUSU ;
DR   P57566, RPOA_BUCAI ;  O69232, RPOA_BUCAP ;  P59455, RPOA_BUCBP ;
DR   Q057C9, RPOA_BUCCC ;  B1YRQ5, RPOA_BURA4 ;  Q1BRX4, RPOA_BURCA ;
DR   B1JU48, RPOA_BURCC ;  A0K3Q1, RPOA_BURCH ;  B4E5E6, RPOA_BURCJ ;
DR   Q0BJ20, RPOA_BURCM ;  A9ADL9, RPOA_BURM1 ;  A3MRY0, RPOA_BURM7 ;
DR   A2S7K2, RPOA_BURM9 ;  Q62GN1, RPOA_BURMA ;  A1V877, RPOA_BURMS ;
DR   A3P087, RPOA_BURP0 ;  Q3JMT9, RPOA_BURP1 ;  A3NEF3, RPOA_BURP6 ;
DR   B2JI39, RPOA_BURP8 ;  B2T725, RPOA_BURPP ;  Q63Q37, RPOA_BURPS ;
DR   Q39KE1, RPOA_BURS3 ;  Q2SU53, RPOA_BURTA ;  A4JAR6, RPOA_BURVG ;
DR   Q13TJ6, RPOA_BURXL ;  A6MM68, RPOA_BUXMI ;  Q7YJU6, RPOA_CALFG ;
DR   A4XLQ2, RPOA_CALS8 ;  A7ZFY7, RPOA_CAMC1 ;  A7H0Y9, RPOA_CAMC5 ;
DR   A0RM36, RPOA_CAMFF ;  A7HZX1, RPOA_CAMHC ;  A8FNQ7, RPOA_CAMJ8 ;
DR   A7H5U5, RPOA_CAMJD ;  Q9PM80, RPOA_CAMJE ;  A1W1J7, RPOA_CAMJJ ;
DR   Q5HSJ6, RPOA_CAMJR ;  A4QKM4, RPOA_CAPBU ;  Q3A9U4, RPOA_CARHZ ;
DR   Q05FK5, RPOA_CARRP ;  B8H4F8, RPOA_CAUCN ;  Q9A8S9, RPOA_CAUCR ;
DR   B0T2E6, RPOA_CAUSK ;  B3PK62, RPOA_CELJU ;  A8SED5, RPOA_CERDE ;
DR   Q8M9V7, RPOA_CHAGL ;  Q1ACG7, RPOA_CHAVU ;  Q5L6Z9, RPOA_CHLAB ;
DR   A2CI44, RPOA_CHLAT ;  Q3APK0, RPOA_CHLCH ;  Q824N1, RPOA_CHLCV ;
DR   Q252X4, RPOA_CHLFF ;  B3EGW3, RPOA_CHLL2 ;  Q9PJN4, RPOA_CHLMU ;
DR   B3QR98, RPOA_CHLP8 ;  B3EP34, RPOA_CHLPB ;  A1BJ07, RPOA_CHLPD ;
DR   Q9Z7S8, RPOA_CHLPN ;  Q8HUH2, RPOA_CHLRE ;  A6MMF4, RPOA_CHLSC ;
DR   B0B881, RPOA_CHLT2 ;  B3QYF0, RPOA_CHLT3 ;  Q3KLJ0, RPOA_CHLTA ;
DR   B0BCE6, RPOA_CHLTB ;  Q8KAJ8, RPOA_CHLTE ;  P0CE08, RPOA_CHLTR ;
DR   P56298, RPOA_CHLVU ;  Q1R0F0, RPOA_CHRSD ;  Q7NQH7, RPOA_CHRVO ;
DR   A8AQJ0, RPOA_CITK8 ;  Q09ME5, RPOA_CITSI ;  A5CU80, RPOA_CLAM3 ;
DR   B0RB72, RPOA_CLAMS ;  Q97EK6, RPOA_CLOAB ;  A7FZ44, RPOA_CLOB1 ;
DR   C3KVM2, RPOA_CLOB6 ;  A6LPU0, RPOA_CLOB8 ;  B2UYD9, RPOA_CLOBA ;
DR   B2TIK4, RPOA_CLOBB ;  A5I7H7, RPOA_CLOBH ;  C1FMS2, RPOA_CLOBJ ;
DR   B1IGC5, RPOA_CLOBK ;  A7GJ45, RPOA_CLOBL ;  B1KSJ6, RPOA_CLOBM ;
DR   B8I808, RPOA_CLOCE ;  Q18CI5, RPOA_CLOD6 ;  B9DYD7, RPOA_CLOK1 ;
DR   A5N4S5, RPOA_CLOK5 ;  A0PXX5, RPOA_CLONN ;  Q0TMS5, RPOA_CLOP1 ;
DR   P0C2E6, RPOA_CLOPE ;  Q0SQH3, RPOA_CLOPS ;  Q890R0, RPOA_CLOTE ;
DR   A3DJK1, RPOA_CLOTH ;  A0A367, RPOA_COFAR ;  Q488Y8, RPOA_COLP3 ;
DR   Q6NJ63, RPOA_CORDI ;  Q8FS33, RPOA_COREF ;  A4QBQ7, RPOA_CORGB ;
DR   Q8NSV2, RPOA_CORGL ;  Q4JTC2, RPOA_CORJK ;  B6J5F7, RPOA_COXB1 ;
DR   B6J238, RPOA_COXB2 ;  A9KD06, RPOA_COXBN ;  A9NAZ5, RPOA_COXBR ;
DR   Q83EQ2, RPOA_COXBU ;  P92225, RPOA_CRIDE ;  A4QKW3, RPOA_CRUWA ;
DR   Q4VZK3, RPOA_CUCSA ;  Q0K645, RPOA_CUPNH ;  Q46WG9, RPOA_CUPPJ ;
DR   B3R7E3, RPOA_CUPTR ;  A8W3F3, RPOA_CUSEX ;  Q49CA2, RPOA_CUSJA ;
DR   Q8SKY1, RPOA_CUSRE ;  Q9TLV2, RPOA_CYACA ;  Q85FU3, RPOA_CYAME ;
DR   P48118, RPOA_CYAPA ;  A6H5L3, RPOA_CYCTA ;  Q11QD8, RPOA_CYTH3 ;
DR   Q0G9T0, RPOA_DAUCA ;  Q47J77, RPOA_DECAR ;  Q3Z953, RPOA_DEHE1 ;
DR   Q3ZZP6, RPOA_DEHSC ;  Q1IX99, RPOA_DEIGD ;  Q9RSJ6, RPOA_DEIRA ;
DR   A9BRX5, RPOA_DELAS ;  C6C1B1, RPOA_DESAD ;  C0Q9U7, RPOA_DESAH ;
DR   B1I1B3, RPOA_DESAP ;  B8IYL7, RPOA_DESDA ;  Q30Z68, RPOA_DESDG ;
DR   B8G1Z4, RPOA_DESHD ;  Q250K4, RPOA_DESHY ;  C4XLK3, RPOA_DESMR ;
DR   A8ZV82, RPOA_DESOH ;  Q6AP43, RPOA_DESPS ;  A4J139, RPOA_DESRM ;
DR   Q72CF4, RPOA_DESVH ;  B8DNK9, RPOA_DESVM ;  A1VE90, RPOA_DESVV ;
DR   A5EX94, RPOA_DICNV ;  A6MMN9, RPOA_DIOEL ;  A4QL51, RPOA_DRANE ;
DR   Q06GW5, RPOA_DRIGR ;  A7ZSI4, RPOA_ECO24 ;  P0A7Z6, RPOA_ECO57 ;
DR   A8A5A0, RPOA_ECOHS ;  A1AGI6, RPOA_ECOK1 ;  Q0TCG6, RPOA_ECOL5 ;
DR   P0A7Z5, RPOA_ECOL6 ;  P0A7Z4, RPOA_ECOLI ;  Q1R637, RPOA_ECOUT ;
DR   Q3YRN2, RPOA_EHRCJ ;  Q2GH33, RPOA_EHRCR ;  Q5FFS1, RPOA_EHRRG ;
DR   Q5HAU5, RPOA_EHRRW ;  Q7H6I5, RPOA_ELYCA ;  Q8MAI9, RPOA_ELYCL ;
DR   Q8MAI8, RPOA_ELYHY ;  Q4G347, RPOA_EMIHU ;  A4WFA3, RPOA_ENT38 ;
DR   Q839D9, RPOA_ENTFA ;  A7MPF8, RPOA_ENTS8 ;  P93974, RPOA_EREDI ;
DR   Q6CZZ5, RPOA_ERWCT ;  Q2N9D7, RPOA_ERYLH ;  Q49KW6, RPOA_EUCGG ;
DR   Q8SL94, RPOA_EUGAN ;  Q8SL92, RPOA_EUGGA ;  P48337, RPOA_EUGGR ;
DR   Q8SL90, RPOA_EUGMY ;  Q8SL88, RPOA_EUGST ;  Q8SL86, RPOA_EUGVI ;
DR   A7HM24, RPOA_FERNB ;  P93968, RPOA_FESFE ;  P93956, RPOA_FESSE ;
DR   A6GZ73, RPOA_FLAPJ ;  Q0RRP3, RPOA_FRAAA ;  Q2JFE8, RPOA_FRASC ;
DR   Q8RE44, RPOA_FUSNN ;  Q5L3R2, RPOA_GEOKA ;  Q39XX9, RPOA_GEOMG ;
DR   Q749B3, RPOA_GEOSL ;  A4IJL4, RPOA_GEOTN ;  Q7NFF5, RPOA_GLOVI ;
DR   A9H3I9, RPOA_GLUDA ;  Q5FU07, RPOA_GLUOX ;  A0ZZ67, RPOA_GOSBA ;
DR   Q2L938, RPOA_GOSHI ;  Q0BUM6, RPOA_GRABC ;  A0M573, RPOA_GRAFK ;
DR   Q6B8X4, RPOA_GRATL ;  O46914, RPOA_GUITH ;  Q7VKF8, RPOA_HAEDU ;
DR   Q4QM97, RPOA_HAEI8 ;  A5UDS2, RPOA_HAEIE ;  A5UHV5, RPOA_HAEIG ;
DR   P43737, RPOA_HAEIN ;  Q0I137, RPOA_HAES1 ;  Q2S937, RPOA_HAHCH ;
DR   A1WV97, RPOA_HALHL ;  Q17ZB4, RPOA_HELAH ;  Q1KXS7, RPOA_HELAN ;
DR   Q7VGB9, RPOA_HELHP ;  B0TC85, RPOA_HELMI ;  Q1CRW7, RPOA_HELPH ;
DR   Q9ZJT5, RPOA_HELPJ ;  P56001, RPOA_HELPY ;  Q2EEW7, RPOA_HELSJ ;
DR   A9B437, RPOA_HERA2 ;  A4G9R3, RPOA_HERAR ;  P92389, RPOA_HETPI ;
DR   Q7H6J2, RPOA_HORBU ;  Q7H6J1, RPOA_HORJU ;  Q7H6J0, RPOA_HORMA ;
DR   P92392, RPOA_HORVU ;  Q5SD25, RPOA_HUPLU ;  B4U772, RPOA_HYDS0 ;
DR   Q0BYD8, RPOA_HYPNA ;  Q5QXV8, RPOA_IDILO ;  A6MMX6, RPOA_ILLOL ;
DR   A7Y3I1, RPOA_IPOPU ;  A6T3H8, RPOA_JANMA ;  Q28US8, RPOA_JANSC ;
DR   Q06RA0, RPOA_JASNU ;  A6W5W5, RPOA_KINRD ;  A6TEU8, RPOA_KLEP7 ;
DR   Q5FM65, RPOA_LACAC ;  Q03PY3, RPOA_LACBA ;  Q035A9, RPOA_LACC3 ;
DR   B3WAJ2, RPOA_LACCB ;  Q1GBJ2, RPOA_LACDA ;  Q04BY9, RPOA_LACDB ;
DR   Q046A0, RPOA_LACGA ;  A8YXN0, RPOA_LACH4 ;  Q74L64, RPOA_LACJO ;
DR   Q9CDY3, RPOA_LACLA ;  A2RNM7, RPOA_LACLM ;  Q02W51, RPOA_LACLS ;
DR   Q88XW0, RPOA_LACPL ;  A5VLH9, RPOA_LACRD ;  B2G8V2, RPOA_LACRJ ;
DR   Q1WSB6, RPOA_LACS1 ;  Q332U5, RPOA_LACSA ;  Q38UT7, RPOA_LACSS ;
DR   C1DAU3, RPOA_LARHH ;  Q1MPP1, RPOA_LAWIP ;  Q5X834, RPOA_LEGPA ;
DR   A5IHP1, RPOA_LEGPC ;  Q5ZYL8, RPOA_LEGPH ;  Q5WZI7, RPOA_LEGPL ;
DR   Q6AD21, RPOA_LEIXX ;  B0SA20, RPOA_LEPBA ;  Q04PW5, RPOA_LEPBJ ;
DR   Q055B7, RPOA_LEPBL ;  B0SSF2, RPOA_LEPBP ;  B1Y7M9, RPOA_LEPCP ;
DR   Q72NI8, RPOA_LEPIC ;  Q9XD09, RPOA_LEPIN ;  A4QLD8, RPOA_LEPVR ;
DR   Q03ZM0, RPOA_LEUMM ;  Q0G9I7, RPOA_LIRTU ;  P66700, RPOA_LISIN ;
DR   C1KZF5, RPOA_LISMC ;  Q71WH2, RPOA_LISMF ;  B8DB34, RPOA_LISMH ;
DR   P66699, RPOA_LISMO ;  A0ALU2, RPOA_LISW6 ;  A4QLM6, RPOA_LOBMA ;
DR   A8Y9B8, RPOA_LOLPR ;  Q8MAI6, RPOA_LOPEL ;  Q9BBQ4, RPOA_LOTJA ;
DR   B9E9L7, RPOA_MACCJ ;  Q2W2L3, RPOA_MAGSA ;  A0L5Z8, RPOA_MAGSM ;
DR   P09562, RPOA_MAIZE ;  Q65QY0, RPOA_MANSM ;  A1TYM2, RPOA_MARAV ;
DR   Q0ANS4, RPOA_MARMM ;  P06270, RPOA_MARPO ;  Q9BBN0, RPOA_MARQU ;
DR   Q6F1W7, RPOA_MESFL ;  Q11HS6, RPOA_MESSB ;  Q9MUV0, RPOA_MESVI ;
DR   B7L0S5, RPOA_METC4 ;  Q605D7, RPOA_METCA ;  Q1H4L2, RPOA_METFK ;
DR   B8IT35, RPOA_METNO ;  B1Z768, RPOA_METPB ;  A2SLD1, RPOA_METPP ;
DR   B1LWP9, RPOA_METRJ ;  B0UHU5, RPOA_METS4 ;  B8EIT5, RPOA_METSB ;
DR   Q2RFS6, RPOA_MOOTA ;  Q09WY5, RPOA_MORIN ;  A0QKU5, RPOA_MYCA1 ;
DR   P66702, RPOA_MYCBO ;  A1KPE3, RPOA_MYCBP ;  Q2SRH9, RPOA_MYCCT ;
DR   Q9RDV6, RPOA_MYCGA ;  P47423, RPOA_MYCGE ;  Q601I9, RPOA_MYCH2 ;
DR   Q4A8J7, RPOA_MYCH7 ;  Q4AAG6, RPOA_MYCHJ ;  Q9X798, RPOA_MYCLE ;
DR   Q6KI29, RPOA_MYCMO ;  Q6MSP9, RPOA_MYCMS ;  Q73S43, RPOA_MYCPA ;
DR   Q8EUD7, RPOA_MYCPE ;  Q50295, RPOA_MYCPN ;  Q98Q08, RPOA_MYCPU ;
DR   A0QSL8, RPOA_MYCS2 ;  Q4A5J0, RPOA_MYCS5 ;  A3PVL8, RPOA_MYCSJ ;
DR   A1UBY5, RPOA_MYCSK ;  P38018, RPOA_MYCSP ;  Q1BD08, RPOA_MYCSS ;
DR   A5U8D3, RPOA_MYCTA ;  P66701, RPOA_MYCTU ;  A0PMB7, RPOA_MYCUA ;
DR   A1T520, RPOA_MYCVP ;  Q1D748, RPOA_MYXXD ;  Q09FS9, RPOA_NANDO ;
DR   A4QLW5, RPOA_NASOF ;  B2A4Q0, RPOA_NATTJ ;  Q5F5V2, RPOA_NEIG1 ;
DR   P66703, RPOA_NEIMA ;  P66704, RPOA_NEIMB ;  A1KRJ9, RPOA_NEIMF ;
DR   Q2GEB6, RPOA_NEOSM ;  Q9TL28, RPOA_NEPOL ;  Q3C1M3, RPOA_NICSY ;
DR   Q33C00, RPOA_NICTO ;  Q0AIH1, RPOA_NITEC ;  Q82X69, RPOA_NITEU ;
DR   Q1QN06, RPOA_NITHX ;  Q2YAX2, RPOA_NITMU ;  Q3J8T8, RPOA_NITOC ;
DR   A6Q1K4, RPOA_NITSB ;  Q3SSU2, RPOA_NITWN ;  Q5Z1K9, RPOA_NOCFA ;
DR   A1SNI8, RPOA_NOCSJ ;  Q8YPK3, RPOA_NOSS1 ;  Q2G5B0, RPOA_NOVAD ;
DR   Q6EW20, RPOA_NYMAL ;  Q8ETV9, RPOA_OCEIH ;  A6X0E2, RPOA_OCHA4 ;
DR   P49465, RPOA_ODOSI ;  Q9MTJ3, RPOA_OENEH ;  Q04G60, RPOA_OENOB ;
DR   B6JEY9, RPOA_OLICO ;  A4QJW3, RPOA_OLIPU ;  Q20F02, RPOA_OLTVI ;
DR   Q6YQZ5, RPOA_ONYPE ;  A5CCI9, RPOA_ORITB ;  B3CT29, RPOA_ORITI ;
DR   Q6ENE2, RPOA_ORYNI ;  P0C498, RPOA_ORYSA ;  P0C499, RPOA_ORYSI ;
DR   P0C500, RPOA_ORYSJ ;  Q0P3L0, RPOA_OSTTA ;  Q68RX5, RPOA_PANGI ;
DR   A6LEG5, RPOA_PARD8 ;  A1B052, RPOA_PARDP ;  A7HWT5, RPOA_PARL1 ;
DR   Q6ME42, RPOA_PARUW ;  P57941, RPOA_PASMU ;  P13911, RPOA_PEA   ;
DR   Q03EE2, RPOA_PEDPA ;  Q3A6M0, RPOA_PELCD ;  Q3B6D6, RPOA_PELLD ;
DR   B4SBX4, RPOA_PELPB ;  A1ALW7, RPOA_PELPD ;  Q4FLP1, RPOA_PELUB ;
DR   Q8MC99, RPOA_PHAAN ;  Q3BAK5, RPOA_PHAAO ;  A0T0K0, RPOA_PHATC ;
DR   A4GGD7, RPOA_PHAVU ;  B4R8P1, RPOA_PHEZH ;  Q7MYH5, RPOA_PHOLL ;
DR   Q6LV91, RPOA_PHOPR ;  P60315, RPOA_PHYPA ;  Q85X01, RPOA_PINKO ;
DR   P41629, RPOA_PINTH ;  Q06GM8, RPOA_PIPCE ;  Q09G14, RPOA_PLAOC ;
DR   A1VJ40, RPOA_POLNA ;  B1XSS7, RPOA_POLNS ;  Q12G77, RPOA_POLSJ ;
DR   A4SUY6, RPOA_POLSQ ;  Q14FC5, RPOA_POPAL ;  A4GYU3, RPOA_POPTR ;
DR   Q7MTP0, RPOA_PORGI ;  P51293, RPOA_PORPU ;  Q1XDJ5, RPOA_PORYE ;
DR   B4S5A1, RPOA_PROA2 ;  Q6A6R1, RPOA_PROAC ;  A3PF25, RPOA_PROM0 ;
DR   A2C4X7, RPOA_PROM1 ;  A8G739, RPOA_PROM2 ;  A2CC51, RPOA_PROM3 ;
DR   A2BYR3, RPOA_PROM5 ;  Q318K7, RPOA_PROM9 ;  Q7V9Y5, RPOA_PROMA ;
DR   Q7V523, RPOA_PROMM ;  Q7UZW6, RPOA_PROMP ;  A2BTB5, RPOA_PROMS ;
DR   Q46IT2, RPOA_PROMT ;  A4SCT6, RPOA_PROVI ;  P92418, RPOA_PSAFR ;
DR   Q7H6F6, RPOA_PSAJU ;  P93960, RPOA_PSARU ;  P93962, RPOA_PSAST ;
DR   Q48D61, RPOA_PSE14 ;  Q15X48, RPOA_PSEA6 ;  A6UZL3, RPOA_PSEA7 ;
DR   Q02T55, RPOA_PSEAB ;  O52760, RPOA_PSEAE ;  Q3ZJ77, RPOA_PSEAK ;
DR   Q1IFU1, RPOA_PSEE4 ;  Q4K557, RPOA_PSEF5 ;  Q3IJI6, RPOA_PSEHT ;
DR   A4XZ65, RPOA_PSEMY ;  A5VXS2, RPOA_PSEP1 ;  Q3K612, RPOA_PSEPF ;
DR   Q7H6G1, RPOA_PSEPI ;  Q88QL1, RPOA_PSEPK ;  Q8L2F8, RPOA_PSEPU ;
DR   Q889U6, RPOA_PSESM ;  Q4ZMR8, RPOA_PSEU2 ;  A4VHQ5, RPOA_PSEU5 ;
DR   Q8WHZ1, RPOA_PSINU ;  Q4FUD1, RPOA_PSYA2 ;  Q1QDG1, RPOA_PSYCK ;
DR   A5WCL4, RPOA_PSYWF ;  Q01569, RPOA_PYRSA ;  Q1LI63, RPOA_RALME ;
DR   B2UEJ3, RPOA_RALPJ ;  Q8XV38, RPOA_RALSO ;  A1XGS0, RPOA_RANMC ;
DR   O21260, RPOA_RECAM ;  A9WSR1, RPOA_RENSM ;  A6MW22, RPOA_RHDSA ;
DR   B3PWU5, RPOA_RHIE6 ;  Q2K9J2, RPOA_RHIEC ;  Q1MIB7, RPOA_RHIL3 ;
DR   Q98N33, RPOA_RHILO ;  B5ZZ57, RPOA_RHILW ;  Q925Z2, RPOA_RHIME ;
DR   P0A4E4, RPOA_RHIRD ;  C3MB03, RPOA_RHISN ;  Q7UIC5, RPOA_RHOBA ;
DR   B6IRT0, RPOA_RHOCS ;  Q21QP9, RPOA_RHOFD ;  Q2IXN6, RPOA_RHOP2 ;
DR   Q07KP2, RPOA_RHOP5 ;  Q6N4V7, RPOA_RHOPA ;  Q211H2, RPOA_RHOPB ;
DR   Q134V3, RPOA_RHOPS ;  B3QBV5, RPOA_RHOPT ;  Q2RQY4, RPOA_RHORT ;
DR   A3PGN5, RPOA_RHOS1 ;  Q3J5P8, RPOA_RHOS4 ;  A4WVI4, RPOA_RHOS5 ;
DR   B9KLB5, RPOA_RHOSK ;  Q0S3E7, RPOA_RHOSR ;  C3PP83, RPOA_RICAE ;
DR   A8GPC6, RPOA_RICAH ;  A8GVD7, RPOA_RICB8 ;  Q1RHP5, RPOA_RICBR ;
DR   A8EZJ2, RPOA_RICCK ;  Q92GZ0, RPOA_RICCN ;  Q4UMQ5, RPOA_RICFE ;
DR   A8F2C3, RPOA_RICM5 ;  Q9ZCS9, RPOA_RICPR ;  C4K2F5, RPOA_RICPU ;
DR   B0BUN6, RPOA_RICRO ;  A8GT45, RPOA_RICRS ;  Q68WA2, RPOA_RICTY ;
DR   A7NR36, RPOA_ROSCS ;  Q16AB8, RPOA_ROSDO ;  A5USG2, RPOA_ROSS1 ;
DR   Q1AU56, RPOA_RUBXD ;  A1AVM5, RPOA_RUTMC ;  Q21M33, RPOA_SACD2 ;
DR   A4FPJ2, RPOA_SACEN ;  Q6L370, RPOA_SACHY ;  Q6ENT2, RPOA_SACOF ;
DR   Q57J56, RPOA_SALCH ;  Q5PK10, RPOA_SALPA ;  Q2S3N9, RPOA_SALRD ;
DR   P0A7Z8, RPOA_SALTI ;  P0A7Z7, RPOA_SALTY ;  P19587, RPOA_SCEOB ;
DR   Q6YLW2, RPOA_SECCE ;  P93964, RPOA_SECST ;  A8GKH3, RPOA_SERP5 ;
DR   A1S243, RPOA_SHEAM ;  A3DA47, RPOA_SHEB5 ;  A6WHV3, RPOA_SHEB8 ;
DR   Q12ST4, RPOA_SHEDO ;  Q089M9, RPOA_SHEFN ;  A3Q9A7, RPOA_SHELP ;
DR   Q8EK47, RPOA_SHEON ;  A4YBV8, RPOA_SHEPC ;  A0KRP9, RPOA_SHESA ;
DR   Q0HNR2, RPOA_SHESM ;  P74963, RPOA_SHESP ;  Q0I080, RPOA_SHESR ;
DR   A1RED9, RPOA_SHESW ;  Q9S0Q8, RPOA_SHEVD ;  Q31VY1, RPOA_SHIBS ;
DR   Q32B56, RPOA_SHIDS ;  Q0T007, RPOA_SHIF8 ;  P0A7Z9, RPOA_SHIFL ;
DR   Q3YWW4, RPOA_SHISS ;  Q5LW32, RPOA_SILPO ;  Q1GK04, RPOA_SILST ;
DR   Q9XQN8, RPOA_SINAL ;  A6U883, RPOA_SINMW ;  Q2NQP7, RPOA_SODGM ;
DR   Q2MIF6, RPOA_SOLBU ;  Q2MI69, RPOA_SOLLC ;  Q2VEE8, RPOA_SOLTU ;
DR   Q01WC0, RPOA_SOLUE ;  A1E9V6, RPOA_SORBI ;  A9FGB8, RPOA_SORC5 ;
DR   Q2PMQ3, RPOA_SOYBN ;  Q1GVN6, RPOA_SPHAL ;  A5V5X5, RPOA_SPHWW ;
DR   O98462, RPOA_SPIMX ;  P06505, RPOA_SPIOL ;  A7X5C4, RPOA_STAA1 ;
DR   Q2FER5, RPOA_STAA3 ;  Q2FW32, RPOA_STAA8 ;  Q2YYM2, RPOA_STAAB ;
DR   Q5HDY4, RPOA_STAAC ;  A6QJ66, RPOA_STAAE ;  P66705, RPOA_STAAM ;
DR   P66706, RPOA_STAAN ;  Q6GEK9, RPOA_STAAR ;  Q6G797, RPOA_STAAS ;
DR   P66707, RPOA_STAAW ;  Q5HM25, RPOA_STAEQ ;  Q8CRI4, RPOA_STAES ;
DR   Q4L888, RPOA_STAHJ ;  Q32RU7, RPOA_STAPU ;  Q49ZE2, RPOA_STAS1 ;
DR   Q06SF7, RPOA_STIHE ;  Q3K3U4, RPOA_STRA1 ;  Q8CX32, RPOA_STRA3 ;
DR   Q8E2B1, RPOA_STRA5 ;  P60312, RPOA_STRCO ;  A8AZJ9, RPOA_STRGC ;
DR   B1W3Y0, RPOA_STRGG ;  Q9X4V6, RPOA_STRGT ;  B4SLH5, RPOA_STRM5 ;
DR   B2FQK8, RPOA_STRMK ;  Q8DS36, RPOA_STRMU ;  P66710, RPOA_STRP1 ;
DR   Q04ML1, RPOA_STRP2 ;  P0DF28, RPOA_STRP3 ;  Q5XEA9, RPOA_STRP6 ;
DR   P66711, RPOA_STRP8 ;  Q1JE33, RPOA_STRPB ;  Q1JNZ1, RPOA_STRPC ;
DR   Q1JJ35, RPOA_STRPD ;  Q1J8Y7, RPOA_STRPF ;  A2RC40, RPOA_STRPG ;
DR   Q48VS3, RPOA_STRPM ;  P66708, RPOA_STRPN ;  P0DF29, RPOA_STRPQ ;
DR   P66709, RPOA_STRR6 ;  A4VYR8, RPOA_STRS2 ;  A3CK90, RPOA_STRSV ;
DR   A4VSH8, RPOA_STRSY ;  Q5LXT7, RPOA_STRT1 ;  Q5M2D9, RPOA_STRT2 ;
DR   Q03IH7, RPOA_STRTD ;  Q30TS3, RPOA_SULDN ;  A6QCS4, RPOA_SULNB ;
DR   Q67JX1, RPOA_SYMTH ;  Q2LQC9, RPOA_SYNAS ;  Q31L30, RPOA_SYNE7 ;
DR   A0LIL7, RPOA_SYNFM ;  Q2JUJ5, RPOA_SYNJA ;  Q2JL74, RPOA_SYNJB ;
DR   O24710, RPOA_SYNP6 ;  A5GIS2, RPOA_SYNPW ;  Q7U4H7, RPOA_SYNPX ;
DR   A5GVY3, RPOA_SYNR3 ;  Q0ID28, RPOA_SYNS3 ;  Q3AW70, RPOA_SYNS9 ;
DR   Q3AMQ3, RPOA_SYNSC ;  Q0AUK9, RPOA_SYNWW ;  P73297, RPOA_SYNY3 ;
DR   Q7GED0, RPOA_TAECM ;  Q60F88, RPOA_TAKLE ;  A0T0Z4, RPOA_THAPS ;
DR   Q9KWU8, RPOA_THEAQ ;  Q8DML0, RPOA_THEEB ;  Q47LM1, RPOA_THEFY ;
DR   A8F4T9, RPOA_THELT ;  A6LLP1, RPOA_THEM4 ;  Q9X1I2, RPOA_THEMA ;
DR   A5IMB1, RPOA_THEP1 ;  B0KCM8, RPOA_THEP3 ;  B0K5S1, RPOA_THEPX ;
DR   Q72I32, RPOA_THET2 ;  Q5SHR6, RPOA_THET8 ;  Q9Z9H6, RPOA_THETH ;
DR   Q8R7Y2, RPOA_THETN ;  P92439, RPOA_THIBE ;  Q31IV8, RPOA_THICR ;
DR   Q3SLM4, RPOA_THIDA ;  B8GV33, RPOA_THISH ;  P06269, RPOA_TOBAC ;
DR   C4L7V5, RPOA_TOLAT ;  Q73PK8, RPOA_TREDE ;  O83242, RPOA_TREPA ;
DR   Q110D1, RPOA_TRIEI ;  Q820D8, RPOA_TROW8 ;  Q820D4, RPOA_TROWT ;
DR   Q9PQN4, RPOA_UREPA ;  C5CQ75, RPOA_VARPS ;  A1WK92, RPOA_VEREI ;
DR   A5CXI9, RPOA_VESOH ;  A5F572, RPOA_VIBC3 ;  Q9KP08, RPOA_VIBCH ;
DR   C3LRN3, RPOA_VIBCM ;  Q5E889, RPOA_VIBF1 ;  B5FGE1, RPOA_VIBFM ;
DR   A7N0H8, RPOA_VIBHB ;  Q87SZ0, RPOA_VIBPA ;  B7VLD2, RPOA_VIBSL ;
DR   Q8DE63, RPOA_VIBVU ;  Q7MPG4, RPOA_VIBVY ;  Q0ZIY7, RPOA_VITVI ;
DR   P12073, RPOA_WHEAT ;  Q8D1Y8, RPOA_WIGBR ;  Q73HA9, RPOA_WOLPM ;
DR   Q7M8F7, RPOA_WOLSU ;  Q5GSW7, RPOA_WOLTR ;  P0A0Y2, RPOA_XANAC ;
DR   Q3BWV9, RPOA_XANC5 ;  Q4URG3, RPOA_XANC8 ;  B0RU58, RPOA_XANCB ;
DR   P0A0Y1, RPOA_XANCP ;  Q2P009, RPOA_XANOM ;  B2SQT4, RPOA_XANOP ;
DR   Q5GWV9, RPOA_XANOR ;  A7IPP6, RPOA_XANP2 ;  B2I8J3, RPOA_XYLF2 ;
DR   P66712, RPOA_XYLFA ;  B0U5M3, RPOA_XYLFM ;  P66713, RPOA_XYLFT ;
DR   A1JS01, RPOA_YERE8 ;  A7FNL0, RPOA_YERP3 ;  Q1C2X1, RPOA_YERPA ;
DR   Q8ZJ87, RPOA_YERPE ;  Q1CCW8, RPOA_YERPN ;  A4TH15, RPOA_YERPP ;
DR   Q664U6, RPOA_YERPS ;  Q32RM8, RPOA_ZYGCR ;  Q5NQ40, RPOA_ZYMMO ;
DR   O28392, RPOB1_ARCFU;  Q8HTL6, RPOB1_CHLRE;  Q8GCR6, RPOB1_ENTFC;
DR   B0R8D5, RPOB1_HALS3;  P0CX03, RPOB1_HALSA;  A6YGD9, RPOB1_LEPTE;
DR   Q60181, RPOB1_METJA;  O27124, RPOB1_METTH;  P09845, RPOB1_METTW;
DR   P41557, RPOB1_METVS;  Q5YQP4, RPOB1_NOCFA;  Q1KVX4, RPOB1_SCEOB;
DR   Q06SE7, RPOB1_STIHE;  Q8HTL7, RPOB2_CHLRE;  Q8GCR4, RPOB2_ENTFC;
DR   B0R8D6, RPOB2_HALS3;  P0CX04, RPOB2_HALSA;  A6YGE0, RPOB2_LEPTE;
DR   Q58444, RPOB2_METJA;  O27123, RPOB2_METTH;  P09844, RPOB2_METTW;
DR   P41558, RPOB2_METVS;  Q5YPE0, RPOB2_NOCFA;  Q1KVX5, RPOB2_SCEOB;
DR   Q06SF4, RPOB2_STIHE;  Q8GCR5, RPOB3_ENTFC;  Q8GCR3, RPOB4_ENTFC;
DR   Q17VN6, RPOBC_HELAH;  Q7VJ82, RPOBC_HELHP;  Q1CS68, RPOBC_HELPH;
DR   Q9ZK23, RPOBC_HELPJ;  B2UUV9, RPOBC_HELPS;  O25806, RPOBC_HELPY;
DR   Q73IW9, RPOBC_WOLPM;  Q7MA56, RPOBC_WOLSU;  Q5GRY9, RPOBC_WOLTR;
DR   A9NEL7, RPOB_ACHLI ;  A1TVT0, RPOB_ACIAC ;  Q6FF90, RPOB_ACIAD ;
DR   B7H1J8, RPOB_ACIB3 ;  B7I360, RPOB_ACIB5 ;  B2I1Z1, RPOB_ACIBC ;
DR   Q1IHH4, RPOB_ACIBL ;  B0VLZ6, RPOB_ACIBS ;  A3M1G3, RPOB_ACIBT ;
DR   B0VDI0, RPOB_ACIBY ;  A0LRL3, RPOB_ACIC1 ;  A5FZX1, RPOB_ACICJ ;
DR   B9MH47, RPOB_ACIET ;  B7J460, RPOB_ACIF2 ;  B5ELX2, RPOB_ACIF5 ;
DR   A1WCM9, RPOB_ACISJ ;  A9LYH7, RPOB_ACOAM ;  Q3V542, RPOB_ACOCL ;
DR   Q5QA72, RPOB_ACOGR ;  A3N325, RPOB_ACTP2 ;  B0BSF5, RPOB_ACTPJ ;
DR   A6VKC5, RPOB_ACTSZ ;  Q85FM7, RPOB_ADICA ;  A0KQA5, RPOB_AERHH ;
DR   A4SHU9, RPOB_AERS4 ;  A4QJA7, RPOB_AETCO ;  A4QJJ1, RPOB_AETGR ;
DR   B9JDS1, RPOB_AGRRK ;  A1E9Z8, RPOB_AGRST ;  Q8UE08, RPOB_AGRT5 ;
DR   B9JVM8, RPOB_AGRVS ;  Q0VSM2, RPOB_ALCBS ;  Q0ABI2, RPOB_ALHEH ;
DR   B6ENR3, RPOB_ALISL ;  A6TWJ0, RPOB_ALKMQ ;  A8MLD2, RPOB_ALKOO ;
DR   P60282, RPOB_AMBTC ;  Q9L637, RPOB_AMYMD ;  B8JB70, RPOB_ANAD2 ;
DR   Q2II86, RPOB_ANADE ;  A7HCH7, RPOB_ANADF ;  Q8KWX4, RPOB_ANAMF ;
DR   Q5PBG4, RPOB_ANAMM ;  Q9AIU3, RPOB_ANAPH ;  Q2GJ68, RPOB_ANAPZ ;
DR   B4UDT2, RPOB_ANASK ;  B9MQG5, RPOB_ANATD ;  Q3M5D0, RPOB_ANAVT ;
DR   A2T324, RPOB_ANGEV ;  Q85BW1, RPOB_ANTFO ;  O67762, RPOB_AQUAE ;
DR   Q9X6Y1, RPOB_AQUPY ;  A4QK10, RPOB_ARAHI ;  P50546, RPOB_ARATH ;
DR   A8EVZ4, RPOB_ARCB4 ;  Q5P339, RPOB_AROAE ;  A1R8V4, RPOB_ARTAT ;
DR   A0JZ93, RPOB_ARTS2 ;  P27059, RPOB_ASTLO ;  Q8S8X9, RPOB_ATRBE ;
DR   Q2NJ15, RPOB_AYWBP ;  A8HTY8, RPOB_AZOC5 ;  A1KB34, RPOB_AZOSB ;
DR   C1DKK5, RPOB_AZOVD ;  A7Z0M9, RPOB_BACA2 ;  C3P9P7, RPOB_BACAA ;
DR   C3LJ74, RPOB_BACAC ;  A0R8H2, RPOB_BACAH ;  Q81VT8, RPOB_BACAN ;
DR   Q73FA4, RPOB_BACC1 ;  B7IT11, RPOB_BACC2 ;  C1ET31, RPOB_BACC3 ;
DR   B7HJ40, RPOB_BACC4 ;  B7HQT6, RPOB_BACC7 ;  B9IZI6, RPOB_BACCQ ;
DR   Q81J48, RPOB_BACCR ;  Q63H98, RPOB_BACCZ ;  Q5L897, RPOB_BACFN ;
DR   Q64NJ7, RPOB_BACFR ;  Q9Z9M2, RPOB_BACHD ;  Q6HPR6, RPOB_BACHK ;
DR   Q65PB5, RPOB_BACLD ;  A8F976, RPOB_BACP2 ;  Q5WLS0, RPOB_BACSK ;
DR   P37870, RPOB_BACSU ;  Q8A469, RPOB_BACTN ;  A6KYK3, RPOB_BACV8 ;
DR   A9VP69, RPOB_BACWK ;  A1USC8, RPOB_BARBK ;  Q9KJG4, RPOB_BARHE ;
DR   Q9KJM5, RPOB_BARQU ;  A9ISG1, RPOB_BART1 ;  A4QK97, RPOB_BARVE ;
DR   Q1LSX7, RPOB_BAUCH ;  Q6MJ09, RPOB_BDEBA ;  A1A317, RPOB_BIFAA ;
DR   B3DTE2, RPOB_BIFLD ;  Q8G514, RPOB_BIFLO ;  B7GUG7, RPOB_BIFLS ;
DR   Q06J17, RPOB_BIGNA ;  Q7VRP7, RPOB_BLOFL ;  Q492B9, RPOB_BLOPB ;
DR   Q2L2M3, RPOB_BORA1 ;  Q0SNB8, RPOB_BORAP ;  Q7WRD9, RPOB_BORBR ;
DR   Q59191, RPOB_BORBU ;  B7J1W1, RPOB_BORBZ ;  B5RLU9, RPOB_BORDL ;
DR   Q661M9, RPOB_BORGA ;  B2S092, RPOB_BORHD ;  Q7W2G9, RPOB_BORPA ;
DR   A9IJ25, RPOB_BORPD ;  Q7W0R9, RPOB_BORPE ;  B5RRJ7, RPOB_BORRA ;
DR   A1QZH7, RPOB_BORT9 ;  Q89J74, RPOB_BRAJA ;  A5ELN7, RPOB_BRASB ;
DR   A4YSI1, RPOB_BRASO ;  C0ZIH0, RPOB_BREBN ;  B2S687, RPOB_BRUA1 ;
DR   Q2YM15, RPOB_BRUA2 ;  Q57CP8, RPOB_BRUAB ;  A9M5R0, RPOB_BRUC2 ;
DR   C0RJL1, RPOB_BRUMB ;  Q8YHP8, RPOB_BRUME ;  A5VR15, RPOB_BRUO2 ;
DR   B0CH41, RPOB_BRUSI ;  Q8G069, RPOB_BRUSU ;  B8D8J6, RPOB_BUCA5 ;
DR   P57146, RPOB_BUCAI ;  P41184, RPOB_BUCAP ;  B8D6V0, RPOB_BUCAT ;
DR   Q89B20, RPOB_BUCBP ;  Q058E5, RPOB_BUCCC ;  B1YRC2, RPOB_BURA4 ;
DR   Q1BRU0, RPOB_BURCA ;  B1JU14, RPOB_BURCC ;  A0K3L7, RPOB_BURCH ;
DR   B4E5B2, RPOB_BURCJ ;  Q0BJ54, RPOB_BURCM ;  A9ADI5, RPOB_BURM1 ;
DR   A3MRU5, RPOB_BURM7 ;  A2S7G6, RPOB_BURM9 ;  P0C151, RPOB_BURMA ;
DR   A1V8B2, RPOB_BURMS ;  A3P0C5, RPOB_BURP0 ;  Q3JMQ3, RPOB_BURP1 ;
DR   A3NEI7, RPOB_BURP6 ;  B2JIH4, RPOB_BURP8 ;  B2T759, RPOB_BURPP ;
DR   Q63Q03, RPOB_BURPS ;  Q39KH5, RPOB_BURS3 ;  Q2SU19, RPOB_BURTA ;
DR   A4JAN2, RPOB_BURVG ;  Q13TG2, RPOB_BURXL ;  A6MM28, RPOB_BUXMI ;
DR   Q7YJX8, RPOB_CALFG ;  A4XI30, RPOB_CALS8 ;  A0RQI5, RPOB_CAMFF ;
DR   A8FKR3, RPOB_CAMJ8 ;  Q46124, RPOB_CAMJE ;  A1VYJ4, RPOB_CAMJJ ;
DR   Q5HVY9, RPOB_CAMJR ;  B9KFG7, RPOB_CAMLR ;  A4QKI4, RPOB_CAPBU ;
DR   Q3A9Q7, RPOB_CARHZ ;  Q05FH8, RPOB_CARRP ;  B8GZW7, RPOB_CAUCN ;
DR   Q9AAU2, RPOB_CAUCR ;  B0SUP7, RPOB_CAUSK ;  B3PK30, RPOB_CELJU ;
DR   A8SE86, RPOB_CERDE ;  Q8MA12, RPOB_CHAGL ;  Q1ACN6, RPOB_CHAVU ;
DR   A9WH12, RPOB_CHLAA ;  Q5L5I3, RPOB_CHLAB ;  B8G4U9, RPOB_CHLAD ;
DR   Q19V98, RPOB_CHLAT ;  Q3ATP5, RPOB_CHLCH ;  Q822J1, RPOB_CHLCV ;
DR   Q255E6, RPOB_CHLFF ;  P56869, RPOB_CHLMU ;  A1BD23, RPOB_CHLPD ;
DR   Q9Z9A0, RPOB_CHLPN ;  A6MMB4, RPOB_CHLSC ;  B9LL91, RPOB_CHLSY ;
DR   B0B7N1, RPOB_CHLT2 ;  Q3KM47, RPOB_CHLTA ;  B0BBU6, RPOB_CHLTB ;
DR   Q8KG15, RPOB_CHLTE ;  P0CE09, RPOB_CHLTR ;  P56299, RPOB_CHLVU ;
DR   Q1R0I2, RPOB_CHRSD ;  Q7NQE6, RPOB_CHRVO ;  A8AKT9, RPOB_CITK8 ;
DR   Q09MI6, RPOB_CITSI ;  A5CUC7, RPOB_CLAM3 ;  B0RB25, RPOB_CLAMS ;
DR   Q97EG9, RPOB_CLOAB ;  A7FZ77, RPOB_CLOB1 ;  C3KVQ9, RPOB_CLOB6 ;
DR   A6LPQ4, RPOB_CLOB8 ;  B2UYA3, RPOB_CLOBA ;  B2TIG8, RPOB_CLOBB ;
DR   A5I7L4, RPOB_CLOBH ;  C1FMV9, RPOB_CLOBJ ;  B1IGG2, RPOB_CLOBK ;
DR   A7GJ82, RPOB_CLOBL ;  B1KSN3, RPOB_CLOBM ;  Q18CF1, RPOB_CLOD6 ;
DR   B9DYA1, RPOB_CLOK1 ;  A5N4N9, RPOB_CLOK5 ;  A0PXT8, RPOB_CLONN ;
DR   Q0TMN8, RPOB_CLOP1 ;  P0C2E7, RPOB_CLOPE ;  Q0SQD6, RPOB_CLOPS ;
DR   Q890N4, RPOB_CLOTE ;  A3DIZ4, RPOB_CLOTH ;  A0A327, RPOB_COFAR ;
DR   Q47UV9, RPOB_COLP3 ;  P60280, RPOB_CORDI ;  Q8FS97, RPOB_COREF ;
DR   A4QBG2, RPOB_CORGB ;  Q8NT26, RPOB_CORGL ;  Q4JT32, RPOB_CORJK ;
DR   C4LL71, RPOB_CORK4 ;  B1VES1, RPOB_CORU7 ;  B6J270, RPOB_COXB2 ;
DR   A9KD39, RPOB_COXBN ;  A9NAL4, RPOB_COXBR ;  P0C8S4, RPOB_COXBU ;
DR   A4QKS3, RPOB_CRUWA ;  Q4VZP1, RPOB_CUCSA ;  Q0K606, RPOB_CUPNH ;
DR   Q46WD4, RPOB_CUPPJ ;  B3R7T6, RPOB_CUPTR ;  A8W3B6, RPOB_CUSEX ;
DR   A7M958, RPOB_CUSRE ;  Q9TM35, RPOB_CYACA ;  Q85FR7, RPOB_CYAME ;
DR   P48119, RPOB_CYAPA ;  A6H5F9, RPOB_CYCTA ;  Q11QA5, RPOB_CYTH3 ;
DR   Q0G9X0, RPOB_DAUCA ;  Q47JB0, RPOB_DECAR ;  Q3Z8V4, RPOB_DEHE1 ;
DR   A5FRK5, RPOB_DEHSB ;  Q3ZX01, RPOB_DEHSC ;  Q1J0P6, RPOB_DEIGD ;
DR   Q9RVV9, RPOB_DEIRA ;  A9BR98, RPOB_DELAS ;  B8FEU1, RPOB_DESAA ;
DR   C6C179, RPOB_DESAD ;  C0Q9X9, RPOB_DESAH ;  B8J1A8, RPOB_DESDA ;
DR   Q30X05, RPOB_DESDG ;  B8G1V8, RPOB_DESHD ;  Q250P0, RPOB_DESHY ;
DR   C4XIN9, RPOB_DESMR ;  A8ZV51, RPOB_DESOH ;  Q6AP78, RPOB_DESPS ;
DR   A4J103, RPOB_DESRM ;  Q727C7, RPOB_DESVH ;  B8DLM7, RPOB_DESVM ;
DR   A1VAJ6, RPOB_DESVV ;  A5EX70, RPOB_DICNV ;  A8LM40, RPOB_DINSH ;
DR   A6MMJ9, RPOB_DIOEL ;  A4QL11, RPOB_DRANE ;  Q06H05, RPOB_DRIGR ;
DR   A7ZUK1, RPOB_ECO24 ;  B7UPE2, RPOB_ECO27 ;  B7MIX3, RPOB_ECO45 ;
DR   B7LA80, RPOB_ECO55 ;  P0A8V4, RPOB_ECO57 ;  B5Z083, RPOB_ECO5E ;
DR   B7NRR5, RPOB_ECO7I ;  B7MRB3, RPOB_ECO81 ;  B7M734, RPOB_ECO8A ;
DR   C5A0S7, RPOB_ECOBW ;  B1XBY9, RPOB_ECODH ;  A8A786, RPOB_ECOHS ;
DR   A1AIF9, RPOB_ECOK1 ;  Q0TA78, RPOB_ECOL5 ;  P0A8V3, RPOB_ECOL6 ;
DR   B1IUR0, RPOB_ECOLC ;  P0A8V2, RPOB_ECOLI ;  B7NFS7, RPOB_ECOLU ;
DR   B6I5J7, RPOB_ECOSE ;  B1LNT9, RPOB_ECOSM ;  Q1R5V3, RPOB_ECOUT ;
DR   C5BHE3, RPOB_EDWI9 ;  Q3YST5, RPOB_EHRCJ ;  Q8KWX2, RPOB_EHRCR ;
DR   Q5FFD9, RPOB_EHRRG ;  Q93MK8, RPOB_EHRRI ;  Q5HC05, RPOB_EHRRW ;
DR   Q93MK9, RPOB_EHRSE ;  Q7YN57, RPOB_EIMTE ;  Q4G3A7, RPOB_EMIHU ;
DR   A4W5A7, RPOB_ENT38 ;  Q82Z40, RPOB_ENTFA ;  A7MQQ9, RPOB_ENTS8 ;
DR   Q6DAN0, RPOB_ERWCT ;  B2VG96, RPOB_ERWT9 ;  Q2N5Q7, RPOB_ERYLH ;
DR   B7LUL5, RPOB_ESCF3 ;  Q49L06, RPOB_EUCGG ;  P23579, RPOB_EUGGR ;
DR   C4KZQ4, RPOB_EXISA ;  A7HNY2, RPOB_FERNB ;  A5FIJ3, RPOB_FLAJ1 ;
DR   A6GYU0, RPOB_FLAPJ ;  Q0RRT0, RPOB_FRAAA ;  B0TX10, RPOB_FRAP2 ;
DR   Q2JFI5, RPOB_FRASC ;  A8LC64, RPOB_FRASN ;  Q14JT5, RPOB_FRAT1 ;
DR   A7NEC0, RPOB_FRATF ;  Q2A1M7, RPOB_FRATH ;  B2SFD6, RPOB_FRATM ;
DR   A0Q867, RPOB_FRATN ;  Q0BKC5, RPOB_FRATO ;  Q5NID2, RPOB_FRATT ;
DR   A4IW99, RPOB_FRATW ;  Q8RHI6, RPOB_FUSNN ;  B5EFP3, RPOB_GEOBB ;
DR   Q5L405, RPOB_GEOKA ;  B3E7S8, RPOB_GEOLS ;  Q39Y13, RPOB_GEOMG ;
DR   B9M6V2, RPOB_GEOSF ;  Q748Y6, RPOB_GEOSL ;  C6E4R4, RPOB_GEOSM ;
DR   A4IJI1, RPOB_GEOTN ;  A5GAY1, RPOB_GEOUR ;  Q7NIA0, RPOB_GLOVI ;
DR   Q5FTX7, RPOB_GLUOX ;  A6BM50, RPOB_GNEPA ;  A0ZZ27, RPOB_GOSBA ;
DR   Q2L8Z9, RPOB_GOSHI ;  Q0BUQ6, RPOB_GRABC ;  A0M3Y9, RPOB_GRAFK ;
DR   Q6B8R8, RPOB_GRATL ;  O78485, RPOB_GUITH ;  Q7VKL7, RPOB_HAEDU ;
DR   Q4QN33, RPOB_HAEI8 ;  A5U9X8, RPOB_HAEIE ;  A5UH20, RPOB_HAEIG ;
DR   P43738, RPOB_HAEIN ;  B8F741, RPOB_HAEPS ;  Q0I5B7, RPOB_HAES1 ;
DR   B0URZ6, RPOB_HAES2 ;  Q2S905, RPOB_HAHCH ;  A1WVC9, RPOB_HALHL ;
DR   C4K4F1, RPOB_HAMD5 ;  Q1KXX2, RPOB_HELAN ;  B0TC48, RPOB_HELMI ;
DR   Q2EEX2, RPOB_HELSJ ;  A9B6J3, RPOB_HERA2 ;  A4G9U5, RPOB_HERAR ;
DR   P36440, RPOB_HETCA ;  A1E9I1, RPOB_HORVU ;  Q5SCX8, RPOB_HUPLU ;
DR   Q0BYA7, RPOB_HYPNA ;  Q5QWA5, RPOB_IDILO ;  A6MMT6, RPOB_ILLOL ;
DR   A7Y3B9, RPOB_IPOPU ;  A6T3L3, RPOB_JANMA ;  Q28UX7, RPOB_JANSC ;
DR   Q06RD9, RPOB_JASNU ;  A6W5T0, RPOB_KINRD ;  B5XYF5, RPOB_KLEP3 ;
DR   A6TGP0, RPOB_KLEP7 ;  C5CGD9, RPOB_KOSOT ;  Q5FM97, RPOB_LACAC ;
DR   Q03PU9, RPOB_LACBA ;  Q034X0, RPOB_LACC3 ;  B3WAM8, RPOB_LACCB ;
DR   Q1GBM5, RPOB_LACDA ;  Q04C22, RPOB_LACDB ;  Q046D2, RPOB_LACGA ;
DR   A8YXJ8, RPOB_LACH4 ;  Q74L95, RPOB_LACJO ;  Q9CEN6, RPOB_LACLA ;
DR   A2RML9, RPOB_LACLM ;  Q02X59, RPOB_LACLS ;  Q88XZ3, RPOB_LACPL ;
DR   A5VLL4, RPOB_LACRD ;  Q1WVA5, RPOB_LACS1 ;  Q56P13, RPOB_LACSA ;
DR   Q38UQ2, RPOB_LACSS ;  Q1MPW8, RPOB_LAWIP ;  Q5X866, RPOB_LEGPA ;
DR   A5IHS1, RPOB_LEGPC ;  Q5ZYQ0, RPOB_LEGPH ;  Q5WZL9, RPOB_LEGPL ;
DR   O86094, RPOB_LEGPN ;  Q6ACX5, RPOB_LEIXX ;  A9L988, RPOB_LEMMI ;
DR   B0SAG1, RPOB_LEPBA ;  Q9KK59, RPOB_LEPBI ;  Q04QI9, RPOB_LEPBJ ;
DR   Q054E2, RPOB_LEPBL ;  B0SSI4, RPOB_LEPBP ;  Q72UA8, RPOB_LEPIC ;
DR   Q8F0S2, RPOB_LEPIN ;  A4QL98, RPOB_LEPVR ;  B1MVW8, RPOB_LEUCK ;
DR   Q03V60, RPOB_LEUMM ;  P41187, RPOB_LIBAF ;  P36251, RPOB_LIBAS ;
DR   Q0G9M7, RPOB_LIRTU ;  Q92F22, RPOB_LISIN ;  C1KYJ3, RPOB_LISMC ;
DR   Q724F0, RPOB_LISMF ;  B8DEY8, RPOB_LISMH ;  Q9RLT9, RPOB_LISMO ;
DR   A0AF63, RPOB_LISW6 ;  A4QLI6, RPOB_LOBMA ;  A8Y9G0, RPOB_LOLPR ;
DR   Q9BBS9, RPOB_LOTJA ;  B1HMZ6, RPOB_LYSSC ;  B9E8Q5, RPOB_MACCJ ;
DR   Q2W2I1, RPOB_MAGSA ;  A0L5W6, RPOB_MAGSM ;  P16023, RPOB_MAIZE ;
DR   Q65W41, RPOB_MANSM ;  A1TYJ0, RPOB_MARAV ;  Q0ANP3, RPOB_MARMM ;
DR   A6W399, RPOB_MARMS ;  P06272, RPOB_MARPO ;  Q6F0L7, RPOB_MESFL ;
DR   Q11HB3, RPOB_MESSB ;  Q9MUS5, RPOB_MESVI ;  B7KN45, RPOB_METC4 ;
DR   Q60A06, RPOB_METCA ;  A9W8N8, RPOB_METEP ;  Q1H4P4, RPOB_METFK ;
DR   B3E163, RPOB_METI4 ;  B8IS78, RPOB_METNO ;  B1ZGS0, RPOB_METPB ;
DR   A2SLG5, RPOB_METPP ;  B1LY43, RPOB_METRJ ;  B0UHX6, RPOB_METS4 ;
DR   Q2RFN9, RPOB_MOOTA ;  Q09X25, RPOB_MORIN ;  A0QL49, RPOB_MYCA1 ;
DR   P0A681, RPOB_MYCBO ;  A1KGE7, RPOB_MYCBP ;  Q2ST48, RPOB_MYCCT ;
DR   P47715, RPOB_MYCGA ;  P47583, RPOB_MYCGE ;  A4T1P4, RPOB_MYCGI ;
DR   Q5ZZS1, RPOB_MYCH2 ;  Q4A7A9, RPOB_MYCH7 ;  Q4A969, RPOB_MYCHJ ;
DR   B8ZSC7, RPOB_MYCLB ;  P30760, RPOB_MYCLE ;  B2HSJ3, RPOB_MYCMM ;
DR   Q6KI09, RPOB_MYCMO ;  Q6MRX6, RPOB_MYCMS ;  Q73SE4, RPOB_MYCPA ;
DR   Q8EWX1, RPOB_MYCPE ;  P78013, RPOB_MYCPN ;  Q9RQZ7, RPOB_MYCPR ;
DR   Q98Q23, RPOB_MYCPU ;  P60281, RPOB_MYCS2 ;  Q4A5S7, RPOB_MYCS5 ;
DR   A3PV78, RPOB_MYCSJ ;  A1UBJ3, RPOB_MYCSK ;  Q50388, RPOB_MYCSM ;
DR   Q1BDF0, RPOB_MYCSS ;  A5U052, RPOB_MYCTA ;  P0A680, RPOB_MYCTU ;
DR   A0PM24, RPOB_MYCUA ;  A1T4J2, RPOB_MYCVP ;  Q1D7U3, RPOB_MYXXD ;
DR   Q09FW9, RPOB_NANDO ;  A4QLS5, RPOB_NASOF ;  Q5F5R5, RPOB_NEIG1 ;
DR   B4RQW2, RPOB_NEIG2 ;  P57009, RPOB_NEIMA ;  Q59622, RPOB_NEIMB ;
DR   A1KRG6, RPOB_NEIMF ;  Q9NJN5, RPOB_NEOCA ;  Q2GD90, RPOB_NEOSM ;
DR   Q9TL06, RPOB_NEPOL ;  Q3C1G7, RPOB_NICSY ;  Q33C46, RPOB_NICTO ;
DR   Q0AF53, RPOB_NITEC ;  Q82T75, RPOB_NITEU ;  Q1QN44, RPOB_NITHX ;
DR   Q2YB05, RPOB_NITMU ;  Q3J8Q7, RPOB_NITOC ;  A6Q1M3, RPOB_NITSB ;
DR   Q3SSY0, RPOB_NITWN ;  A1SEK1, RPOB_NOCSJ ;  P22703, RPOB_NOSS1 ;
DR   Q2GCD7, RPOB_NOVAD ;  P41452, RPOB_NPVAC ;  O12934, RPOB_NPVOP ;
DR   O57030, RPOB_NPVSL ;  Q6EW56, RPOB_NYMAL ;  Q8ETY8, RPOB_OCEIH ;
DR   A6X0A9, RPOB_OCHA4 ;  P49466, RPOB_ODOSI ;  Q9MTM5, RPOB_OENEH ;
DR   Q04E85, RPOB_OENOB ;  A4QJS5, RPOB_OLIPU ;  Q20EX1, RPOB_OLTVI ;
DR   Q6YQW3, RPOB_ONYPE ;  A5CC93, RPOB_ORITB ;  Q6ENI4, RPOB_ORYNI ;
DR   P0C501, RPOB_ORYSA ;  P0C502, RPOB_ORYSI ;  P0C503, RPOB_ORYSJ ;
DR   Q0P3M6, RPOB_OSTTA ;  Q68S14, RPOB_PANGI ;  A6LE81, RPOB_PARD8 ;
DR   A1B015, RPOB_PARDP ;  A7HWQ4, RPOB_PARL1 ;  Q6MDM1, RPOB_PARUW ;
DR   Q9CK91, RPOB_PASMU ;  C6DHR5, RPOB_PECCP ;  Q03EA9, RPOB_PEDPA ;
DR   Q3A6Q4, RPOB_PELCD ;  Q06FW9, RPOB_PELHO ;  Q3B1H7, RPOB_PELLD ;
DR   A1ALT4, RPOB_PELPD ;  A5D5I2, RPOB_PELTS ;  Q4FLL2, RPOB_PELUB ;
DR   A9BF33, RPOB_PETMO ;  Q3BAP8, RPOB_PHAAO ;  A0T0D7, RPOB_PHATC ;
DR   A4GGA5, RPOB_PHAVU ;  B4R8K5, RPOB_PHEZH ;  Q7N9A4, RPOB_PHOLL ;
DR   Q6LLW2, RPOB_PHOPR ;  B1VAM6, RPOB_PHYAS ;  B3QZH0, RPOB_PHYMT ;
DR   P60283, RPOB_PHYPA ;  Q85X54, RPOB_PINKO ;  P41607, RPOB_PINTH ;
DR   Q06GR8, RPOB_PIPCE ;  P21421, RPOB_PLAFA ;  Q09G54, RPOB_PLAOC ;
DR   A1VTF8, RPOB_POLNA ;  B1XSP3, RPOB_POLNS ;  Q123G3, RPOB_POLSJ ;
DR   A4SUV4, RPOB_POLSQ ;  Q14FG5, RPOB_POPAL ;  A4GYQ0, RPOB_POPTR ;
DR   Q9F3X8, RPOB_PORCN ;  B2RL45, RPOB_PORG3 ;  Q7MX27, RPOB_PORGI ;
DR   P51252, RPOB_PORPU ;  Q1XDN5, RPOB_PORYE ;  Q6A6K6, RPOB_PROAC ;
DR   A3PEX4, RPOB_PROM0 ;  A2C4N2, RPOB_PROM1 ;  A8G6Y6, RPOB_PROM2 ;
DR   A2C6S8, RPOB_PROM3 ;  A9BCH6, RPOB_PROM4 ;  A2BYL1, RPOB_PROM5 ;
DR   Q318Q7, RPOB_PROM9 ;  Q7VA29, RPOB_PROMA ;  B4EYU9, RPOB_PROMH ;
DR   Q7V5P1, RPOB_PROMM ;  Q7V006, RPOB_PROMP ;  A2BT61, RPOB_PROMS ;
DR   Q46J22, RPOB_PROMT ;  Q48D29, RPOB_PSE14 ;  Q15YB1, RPOB_PSEA6 ;
DR   A6UZI1, RPOB_PSEA7 ;  B7V637, RPOB_PSEA8 ;  Q02T87, RPOB_PSEAB ;
DR   Q51561, RPOB_PSEAE ;  Q3ZJ93, RPOB_PSEAK ;  Q1IFX3, RPOB_PSEE4 ;
DR   Q4K526, RPOB_PSEF5 ;  C3K2Y3, RPOB_PSEFS ;  Q3ILP9, RPOB_PSEHT ;
DR   A4XZ97, RPOB_PSEMY ;  A5VXP0, RPOB_PSEP1 ;  Q3K5Y1, RPOB_PSEPF ;
DR   B0KK60, RPOB_PSEPG ;  Q88QP2, RPOB_PSEPK ;  P19175, RPOB_PSEPU ;
DR   B1JDX1, RPOB_PSEPW ;  Q889X8, RPOB_PSESM ;  Q4ZMN7, RPOB_PSEU2 ;
DR   A4VHM3, RPOB_PSEU5 ;  Q8WI24, RPOB_PSINU ;  Q4FQH3, RPOB_PSYA2 ;
DR   Q1Q8P9, RPOB_PSYCK ;  A1T065, RPOB_PSYIN ;  A5WH35, RPOB_PSYWF ;
DR   Q1LI20, RPOB_RALME ;  B2UEN6, RPOB_RALPJ ;  Q8XUZ8, RPOB_RALSO ;
DR   A9WSY0, RPOB_RENSM ;  A6MVX4, RPOB_RHDSA ;  B3PW59, RPOB_RHIE6 ;
DR   Q2K9M4, RPOB_RHIEC ;  Q1MIE9, RPOB_RHIL3 ;  Q98N66, RPOB_RHILO ;
DR   B5ZYS7, RPOB_RHILW ;  Q92QH7, RPOB_RHIME ;  C3MAX2, RPOB_RHISN ;
DR   Q7URW6, RPOB_RHOBA ;  B6IRP6, RPOB_RHOCS ;  C0ZVQ6, RPOB_RHOE4 ;
DR   Q21SF7, RPOB_RHOFD ;  C1AYV9, RPOB_RHOOB ;  Q2IXS0, RPOB_RHOP2 ;
DR   Q07KK7, RPOB_RHOP5 ;  Q6N4R9, RPOB_RHOPA ;  Q211D8, RPOB_RHOPB ;
DR   Q134R8, RPOB_RHOPS ;  B3QC00, RPOB_RHOPT ;  Q2RQV3, RPOB_RHORT ;
DR   A3PGI9, RPOB_RHOS1 ;  Q3J5T0, RPOB_RHOS4 ;  A4WVL6, RPOB_RHOS5 ;
DR   B9KL83, RPOB_RHOSK ;  Q0SFB3, RPOB_RHOSR ;  C3PMH7, RPOB_RICAE ;
DR   A8GMA7, RPOB_RICAH ;  A8GV24, RPOB_RICB8 ;  Q1RHD0, RPOB_RICBR ;
DR   A8EXK8, RPOB_RICCK ;  Q9RH41, RPOB_RICCN ;  Q4UKD4, RPOB_RICFE ;
DR   A8F0P7, RPOB_RICM5 ;  Q9RH43, RPOB_RICMA ;  O52271, RPOB_RICPR ;
DR   C4K1N9, RPOB_RICPU ;  B0BWA9, RPOB_RICRO ;  A8GQW4, RPOB_RICRS ;
DR   P77941, RPOB_RICTY ;  Q160X7, RPOB_ROSDO ;  A5USR7, RPOB_ROSS1 ;
DR   Q1AU22, RPOB_RUBXD ;  A1AX75, RPOB_RUTMC ;  Q21M93, RPOB_SACD2 ;
DR   A4FPP3, RPOB_SACEN ;  Q6L3A7, RPOB_SACHY ;  Q6ENX3, RPOB_SACOF ;
DR   B5F0W7, RPOB_SALA4 ;  A9MHF1, RPOB_SALAR ;  Q57H69, RPOB_SALCH ;
DR   B5FQJ9, RPOB_SALDC ;  B5QYD8, RPOB_SALEP ;  B5RFK1, RPOB_SALG2 ;
DR   B4TCS4, RPOB_SALHS ;  B4T0Y9, RPOB_SALNS ;  Q5PK93, RPOB_SALPA ;
DR   A9N0J4, RPOB_SALPB ;  C0Q2R7, RPOB_SALPC ;  B5BJQ3, RPOB_SALPK ;
DR   Q2S1Q5, RPOB_SALRD ;  B4TQJ5, RPOB_SALSV ;  Q8Z320, RPOB_SALTI ;
DR   P06173, RPOB_SALTY ;  P08036, RPOB_SAPOF ;  A8G8E7, RPOB_SERP5 ;
DR   A1S211, RPOB_SHEAM ;  B8EBL2, RPOB_SHEB2 ;  A3DB95, RPOB_SHEB5 ;
DR   A6WHS1, RPOB_SHEB8 ;  Q12SW6, RPOB_SHEDO ;  Q089R1, RPOB_SHEFN ;
DR   A3Q975, RPOB_SHELP ;  Q8EK74, RPOB_SHEON ;  A8GYW9, RPOB_SHEPA ;
DR   A4YBZ0, RPOB_SHEPC ;  B8CNC5, RPOB_SHEPW ;  A0KRL7, RPOB_SHESA ;
DR   A8G1F5, RPOB_SHESH ;  Q0HNU4, RPOB_SHESM ;  Q0I0B2, RPOB_SHESR ;
DR   A1REA7, RPOB_SHESW ;  Q9KW14, RPOB_SHEVI ;  B1KMZ0, RPOB_SHEWM ;
DR   B2TWH3, RPOB_SHIB3 ;  Q31U10, RPOB_SHIBS ;  Q32AF9, RPOB_SHIDS ;
DR   Q0SY13, RPOB_SHIF8 ;  P0A8V5, RPOB_SHIFL ;  Q3YUZ7, RPOB_SHISS ;
DR   Q589C0, RPOB_SILLA ;  Q5LMQ5, RPOB_SILPO ;  Q1GK49, RPOB_SILST ;
DR   P46818, RPOB_SINAL ;  A6U851, RPOB_SINMW ;  Q2NWR6, RPOB_SODGM ;
DR   Q2MIJ5, RPOB_SOLBU ;  Q2MIA8, RPOB_SOLLC ;  Q2VEI4, RPOB_SOLTU ;
DR   Q01VB1, RPOB_SOLUE ;  A1E9R4, RPOB_SORBI ;  A9GRB1, RPOB_SORC5 ;
DR   Q8HVY5, RPOB_SOYBN ;  Q1GT23, RPOB_SPHAL ;  A5VBZ8, RPOB_SPHWW ;
DR   P47767, RPOB_SPICI ;  P11703, RPOB_SPIOL ;  A7WYW7, RPOB_STAA1 ;
DR   A6TZ19, RPOB_STAA2 ;  Q2FJ98, RPOB_STAA3 ;  P47768, RPOB_STAA8 ;
DR   A5IQ96, RPOB_STAA9 ;  Q2YSB9, RPOB_STAAB ;  Q5HID3, RPOB_STAAC ;
DR   A6QEJ4, RPOB_STAAE ;  Q932F8, RPOB_STAAM ;  P60278, RPOB_STAAN ;
DR   Q6GJC6, RPOB_STAAR ;  Q6GBU5, RPOB_STAAS ;  A8YZP0, RPOB_STAAT ;
DR   P60279, RPOB_STAAW ;  B9DKV0, RPOB_STACT ;  Q5HRL0, RPOB_STAEQ ;
DR   Q8CQ84, RPOB_STAES ;  Q4L3K3, RPOB_STAHJ ;  Q32RW5, RPOB_STAPU ;
DR   Q49V52, RPOB_STAS1 ;  Q3K3L2, RPOB_STRA1 ;  Q8E7J8, RPOB_STRA3 ;
DR   Q8E239, RPOB_STRA5 ;  Q82DQ5, RPOB_STRAW ;  Q9L0L0, RPOB_STRCO ;
DR   C0M7C8, RPOB_STRE4 ;  B4U047, RPOB_STREM ;  A8AZI3, RPOB_STRGC ;
DR   B4SKV6, RPOB_STRM5 ;  B2FQ38, RPOB_STRMK ;  Q8DS46, RPOB_STRMU ;
DR   Q9A1U1, RPOB_STRP1 ;  Q04IK6, RPOB_STRP2 ;  P0DF30, RPOB_STRP3 ;
DR   B5E2F3, RPOB_STRP4 ;  Q5XE97, RPOB_STRP6 ;  C1CA06, RPOB_STRP7 ;
DR   Q8P2Y3, RPOB_STRP8 ;  Q1JE20, RPOB_STRPB ;  Q1JNX8, RPOB_STRPC ;
DR   Q1JJ23, RPOB_STRPD ;  Q1J8X1, RPOB_STRPF ;  A2RC51, RPOB_STRPG ;
DR   B1I8R4, RPOB_STRPI ;  B8ZNW7, RPOB_STRPJ ;  Q48VR1, RPOB_STRPM ;
DR   Q97NQ7, RPOB_STRPN ;  P0DF31, RPOB_STRPQ ;  B5XJ72, RPOB_STRPZ ;
DR   Q8DNF0, RPOB_STRR6 ;  A4VYU3, RPOB_STRS2 ;  C0MEE3, RPOB_STRS7 ;
DR   A3CKD3, RPOB_STRSV ;  A4VSK2, RPOB_STRSY ;  Q5LXV3, RPOB_STRT1 ;
DR   Q5M2F5, RPOB_STRT2 ;  Q03IK2, RPOB_STRTD ;  B9DSZ5, RPOB_STRU0 ;
DR   C1CGP4, RPOB_STRZJ ;  C1CMQ8, RPOB_STRZP ;  C1CTL4, RPOB_STRZT ;
DR   P11513, RPOB_SULAC ;  Q30TP7, RPOB_SULDN ;  A8Z5T3, RPOB_SULMW ;
DR   A6Q6I2, RPOB_SULNB ;  Q67JT3, RPOB_SYMTH ;  Q2LQ87, RPOB_SYNAS ;
DR   Q31N17, RPOB_SYNE7 ;  A0LII4, RPOB_SYNFM ;  Q2JX64, RPOB_SYNJA ;
DR   Q2JJ19, RPOB_SYNJB ;  Q5MZ23, RPOB_SYNP6 ;  A5GNH3, RPOB_SYNPW ;
DR   Q7U8K4, RPOB_SYNPX ;  A5GVF3, RPOB_SYNR3 ;  Q0I7L7, RPOB_SYNS3 ;
DR   Q3AZA4, RPOB_SYNS9 ;  Q3AHX5, RPOB_SYNSC ;  Q0AUH2, RPOB_SYNWW ;
DR   P77965, RPOB_SYNY3 ;  C5BQ39, RPOB_TERTT ;  A0T0R1, RPOB_THAPS ;
DR   B7ICR3, RPOB_THEAB ;  Q03587, RPOB_THEAC ;  Q9KWU7, RPOB_THEAQ ;
DR   P31814, RPOB_THECE ;  Q8DL55, RPOB_THEEB ;  Q47LI5, RPOB_THEFY ;
DR   A8F4G0, RPOB_THELT ;  A6LKB8, RPOB_THEM4 ;  P29398, RPOB_THEMA ;
DR   A5IJW3, RPOB_THEP1 ;  B0KCJ2, RPOB_THEP3 ;  Q4MY95, RPOB_THEPA ;
DR   B0K5G8, RPOB_THEPX ;  B1L935, RPOB_THESQ ;  Q72HM5, RPOB_THET2 ;
DR   Q8RQE9, RPOB_THET8 ;  Q8R7U6, RPOB_THETN ;  Q31IY9, RPOB_THICR ;
DR   Q3SLQ6, RPOB_THIDA ;  B8GV65, RPOB_THISH ;  P06271, RPOB_TOBAC ;
DR   C4LBV2, RPOB_TOLAT ;  Q9MTD3, RPOB_TOXGO ;  Q73JJ7, RPOB_TREDE ;
DR   O83269, RPOB_TREPA ;  Q110H1, RPOB_TRIEI ;  P59642, RPOB_TROW8 ;
DR   P59643, RPOB_TROWH ;  Q93GF2, RPOB_TROWT ;  B1AIH5, RPOB_UREP2 ;
DR   Q9PQV6, RPOB_UREPA ;  B5ZAZ3, RPOB_UREU1 ;  A1WK55, RPOB_VEREI ;
DR   A5CW25, RPOB_VESOH ;  A5F3P5, RPOB_VIBC3 ;  Q9KV30, RPOB_VIBCH ;
DR   Q5E238, RPOB_VIBF1 ;  B5FC88, RPOB_VIBFM ;  A7MXF1, RPOB_VIBHB ;
DR   Q87KQ4, RPOB_VIBPA ;  Q8DD20, RPOB_VIBVU ;  Q7MGR8, RPOB_VIBVY ;
DR   Q0ZJ28, RPOB_VITVI ;  Q9XPS7, RPOB_WHEAT ;  Q8D233, RPOB_WIGBR ;
DR   Q93MK7, RPOB_WOLPI ;  Q8PNT0, RPOB_XANAC ;  Q3BWZ1, RPOB_XANC5 ;
DR   Q4URD2, RPOB_XANC8 ;  B0RU89, RPOB_XANCB ;  Q8PC56, RPOB_XANCP ;
DR   Q2NZX8, RPOB_XANOM ;  B2SQQ1, RPOB_XANOP ;  Q5GWS6, RPOB_XANOR ;
DR   A7IKQ0, RPOB_XANP2 ;  B2IA68, RPOB_XYLF2 ;  Q9PA86, RPOB_XYLFA ;
DR   B0U5X7, RPOB_XYLFM ;  Q87A32, RPOB_XYLFT ;  A1JII0, RPOB_YERE8 ;
DR   A7FNI3, RPOB_YERP3 ;  Q1C1U1, RPOB_YERPA ;  B2K113, RPOB_YERPB ;
DR   Q8ZAP5, RPOB_YERPE ;  A9R0H8, RPOB_YERPG ;  Q1CN78, RPOB_YERPN ;
DR   A4TS29, RPOB_YERPP ;  Q66FQ2, RPOB_YERPS ;  B1JJJ9, RPOB_YERPY ;
DR   Q32RG0, RPOB_ZYGCR ;  Q5NPK5, RPOB_ZYMMO ;  B0C2D1, RPOC1_ACAM1;
DR   A9LYH6, RPOC1_ACOAM;  Q3V543, RPOC1_ACOCL;  Q5QA71, RPOC1_ACOGR;
DR   Q85FM8, RPOC1_ADICA;  A4QJA6, RPOC1_AETCO;  A4QJJ0, RPOC1_AETGR;
DR   A1E9Z9, RPOC1_AGRST;  P60287, RPOC1_AMBTC;  Q3M5C9, RPOC1_ANAVT;
DR   B0YPL9, RPOC1_ANEMR;  A2T323, RPOC1_ANGEV;  Q85CL6, RPOC1_ANTFO;
DR   A4QK09, RPOC1_ARAHI;  P56763, RPOC1_ARATH;  P58131, RPOC1_ASTLO;
DR   Q8S8Y0, RPOC1_ATRBE;  A4QK96, RPOC1_BARVE;  Q06J18, RPOC1_BIGNA;
DR   B3TN43, RPOC1_BRADI;  A6MM27, RPOC1_BUXMI;  Q7YJX9, RPOC1_CALFG;
DR   A4QKI3, RPOC1_CAPBU;  B1A926, RPOC1_CARPA;  A8SE82, RPOC1_CERDE;
DR   Q8MA11, RPOC1_CHAGL;  Q1ACN5, RPOC1_CHAVU;  Q19V99, RPOC1_CHLAT;
DR   A6MMB3, RPOC1_CHLSC;  P56300, RPOC1_CHLVU;  Q09MI7, RPOC1_CITSI;
DR   A0A326, RPOC1_COFAR;  A4QKS2, RPOC1_CRUWA;  B1VKH4, RPOC1_CRYJA;
DR   Q4VZP2, RPOC1_CUCSA;  A8W3B5, RPOC1_CUSEX;  A7M957, RPOC1_CUSRE;
DR   B1WP07, RPOC1_CYAA5;  O19897, RPOC1_CYACA;  B8HTV9, RPOC1_CYAP4;
DR   B7KK78, RPOC1_CYAP7;  B7JWQ8, RPOC1_CYAP8;  P42080, RPOC1_CYAPA;
DR   A6H5F8, RPOC1_CYCTA;  Q0G9X1, RPOC1_DAUCA;  A6MMJ8, RPOC1_DIOEL;
DR   A4QL10, RPOC1_DRANE;  Q06H06, RPOC1_DRIGR;  Q4G3A6, RPOC1_EMIHU;
DR   Q49L07, RPOC1_EUCGG;  P23580, RPOC1_EUGGR;  B2XWP0, RPOC1_FAGEA;
DR   P42074, RPOC1_FISMU;  Q7NDF8, RPOC1_GLOVI;  A6BM51, RPOC1_GNEPA;
DR   A0ZZ26, RPOC1_GOSBA;  Q2L8Z4, RPOC1_GOSHI;  Q6B8R7, RPOC1_GRATL;
DR   B2LMI1, RPOC1_GUIAB;  O78484, RPOC1_GUITH;  Q1KXX1, RPOC1_HELAN;
DR   Q2EEW9, RPOC1_HELSJ;  P36441, RPOC1_HETCA;  A1E9I2, RPOC1_HORVU;
DR   Q5SCX9, RPOC1_HUPLU;  A6MMT5, RPOC1_ILLOL;  A7Y3B6, RPOC1_IPOPU;
DR   Q06RE0, RPOC1_JASNU;  Q56P12, RPOC1_LACSA;  A9L987, RPOC1_LEMMI;
DR   A4QL97, RPOC1_LEPVR;  Q0G9M8, RPOC1_LIRTU;  A4QLI5, RPOC1_LOBMA;
DR   A8Y9G1, RPOC1_LOLPR;  Q9BBS8, RPOC1_LOTJA;  P16024, RPOC1_MAIZE;
DR   B1NWE1, RPOC1_MANES;  P06273, RPOC1_MARPO;  Q9MUS6, RPOC1_MESVI;
DR   B0JSN9, RPOC1_MICAN;  Q09X26, RPOC1_MORIN;  Q09FX0, RPOC1_NANDO;
DR   A4QLS4, RPOC1_NASOF;  Q9TL05, RPOC1_NEPOL;  Q3C1G8, RPOC1_NICSY;
DR   Q33C47, RPOC1_NICTO;  P14563, RPOC1_NOSCO;  B2J199, RPOC1_NOSP7;
DR   P22704, RPOC1_NOSS1;  A1XFU6, RPOC1_NUPAD;  Q6EW57, RPOC1_NYMAL;
DR   P49467, RPOC1_ODOSI;  B2X1Z3, RPOC1_OEDCA;  B0Z4M6, RPOC1_OENAR;
DR   B0Z4W0, RPOC1_OENBI;  Q9MTM4, RPOC1_OENEH;  B0Z544, RPOC1_OENGL;
DR   B0Z5C8, RPOC1_OENPA;  A4QJS4, RPOC1_OLIPU;  Q20EX2, RPOC1_OLTVI;
DR   Q6ENI3, RPOC1_ORYNI;  P0C504, RPOC1_ORYSA;  P0C505, RPOC1_ORYSI;
DR   P0C506, RPOC1_ORYSJ;  Q0P3M5, RPOC1_OSTTA;  Q68S15, RPOC1_PANGI;
DR   B1X3M9, RPOC1_PAUCH;  Q06FX0, RPOC1_PELHO;  Q3BAQ1, RPOC1_PHAAO;
DR   A0T0D8, RPOC1_PHATC;  A4GGA6, RPOC1_PHAVU;  P60288, RPOC1_PHYPA;
DR   Q85WS8, RPOC1_PINKO;  P52733, RPOC1_PINTH;  Q06GR9, RPOC1_PIPCE;
DR   P21422, RPOC1_PLAFA;  Q09G55, RPOC1_PLAOC;  Q14FG6, RPOC1_POPAL;
DR   A4GYP9, RPOC1_POPTR;  P51251, RPOC1_PORPU;  Q1XDN6, RPOC1_PORYE;
DR   P42075, RPOC1_PROHO;  A3PEX3, RPOC1_PROM0;  A2C4N1, RPOC1_PROM1;
DR   A8G6Y5, RPOC1_PROM2;  A2C6S9, RPOC1_PROM3;  A9BCH5, RPOC1_PROM4;
DR   A2BYL0, RPOC1_PROM5;  Q318Q8, RPOC1_PROM9;  P42076, RPOC1_PROMA;
DR   Q7V5P2, RPOC1_PROMM;  Q7V007, RPOC1_PROMP;  A2BT60, RPOC1_PROMS;
DR   Q46J23, RPOC1_PROMT;  P42078, RPOC1_PROSC;  P42077, RPOC1_PROV1;
DR   Q3ZJ92, RPOC1_PSEAK;  Q8WI25, RPOC1_PSINU;  A1XGM9, RPOC1_RANMC;
DR   A6MVX3, RPOC1_RHDSA;  Q6L3A6, RPOC1_SACHY;  Q6ENX2, RPOC1_SACOF;
DR   Q1KVT3, RPOC1_SCEOB;  Q589B9, RPOC1_SILLA;  P46819, RPOC1_SINAL;
DR   Q2MIJ6, RPOC1_SOLBU;  Q2MIA9, RPOC1_SOLLC;  Q2VEI5, RPOC1_SOLTU;
DR   A1E9R5, RPOC1_SORBI;  Q8HVY4, RPOC1_SOYBN;  P11705, RPOC1_SPIOL;
DR   Q32RY3, RPOC1_STAPU;  P42079, RPOC1_SYNE7;  Q2JQT5, RPOC1_SYNJA;
DR   Q2JJ18, RPOC1_SYNJB;  Q55085, RPOC1_SYNP2;  Q5MZ22, RPOC1_SYNP6;
DR   Q55346, RPOC1_SYNPW;  Q7U8K3, RPOC1_SYNPX;  Q55348, RPOC1_SYNPZ;
DR   A5GVF1, RPOC1_SYNR3;  Q0I7L8, RPOC1_SYNS3;  Q3AZA3, RPOC1_SYNS9;
DR   Q3AHX6, RPOC1_SYNSC;  P74177, RPOC1_SYNY3;  A0T0R0, RPOC1_THAPS;
DR   Q8DL56, RPOC1_THEEB;  P12116, RPOC1_TOBAC;  Q110H2, RPOC1_TRIEI;
DR   Q0ZJ29, RPOC1_VITVI;  B2Y1V6, RPOC1_WELMI;  Q9XPS8, RPOC1_WHEAT;
DR   Q32RG1, RPOC1_ZYGCR;  B0C385, RPOC2_ACAM1;  Q3V544, RPOC2_ACOCL;
DR   Q85FM9, RPOC2_ADICA;  A4QJA5, RPOC2_AETCO;  A4QJI9, RPOC2_AETGR;
DR   A1EA00, RPOC2_AGRST;  P60289, RPOC2_AMBTC;  Q3M5C8, RPOC2_ANAVT;
DR   B0YPM0, RPOC2_ANEMR;  A2T322, RPOC2_ANGEV;  Q85C71, RPOC2_ANTFO;
DR   A4QK08, RPOC2_ARAHI;  P56764, RPOC2_ARATH;  P58132, RPOC2_ASTLO;
DR   Q8S8Y1, RPOC2_ATRBE;  A4QK95, RPOC2_BARVE;  Q06J19, RPOC2_BIGNA;
DR   A6MM26, RPOC2_BUXMI;  Q7YJY0, RPOC2_CALFG;  A4QKI2, RPOC2_CAPBU;
DR   B1A925, RPOC2_CARPA;  A8SE78, RPOC2_CERDE;  Q8MA10, RPOC2_CHAGL;
DR   Q1ACN4, RPOC2_CHAVU;  Q19VA0, RPOC2_CHLAT;  Q7PCJ6, RPOC2_CHLRE;
DR   A6MMB2, RPOC2_CHLSC;  P12465, RPOC2_CHLVU;  Q09MI8, RPOC2_CITSI;
DR   A0A325, RPOC2_COFAR;  A4QKS1, RPOC2_CRUWA;  B1VKH5, RPOC2_CRYJA;
DR   Q4VZP3, RPOC2_CUCSA;  A8W3B4, RPOC2_CUSEX;  A7M956, RPOC2_CUSRE;
DR   B1WZT6, RPOC2_CYAA5;  Q9TM34, RPOC2_CYACA;  P48120, RPOC2_CYAPA;
DR   A6H5F7, RPOC2_CYCTA;  Q0G9X2, RPOC2_DAUCA;  A6MMJ7, RPOC2_DIOEL;
DR   A4QL09, RPOC2_DRANE;  Q06H07, RPOC2_DRIGR;  Q4G3A5, RPOC2_EMIHU;
DR   Q49L08, RPOC2_EUCGG;  P23581, RPOC2_EUGGR;  B2XWN9, RPOC2_FAGEA;
DR   P35018, RPOC2_GALSU;  Q7NDF7, RPOC2_GLOVI;  A0ZZ25, RPOC2_GOSBA;
DR   Q2L8Z5, RPOC2_GOSHI;  Q6B8R6, RPOC2_GRATL;  B2LMI2, RPOC2_GUIAB;
DR   O78483, RPOC2_GUITH;  Q1KXX0, RPOC2_HELAN;  Q2EEX0, RPOC2_HELSJ;
DR   A1E9I3, RPOC2_HORVU;  A6MMT4, RPOC2_ILLOL;  A7Y3B4, RPOC2_IPOPU;
DR   Q06RE1, RPOC2_JASNU;  Q56P11, RPOC2_LACSA;  A9L986, RPOC2_LEMMI;
DR   A4QL96, RPOC2_LEPVR;  Q0G9M9, RPOC2_LIRTU;  A4QLI4, RPOC2_LOBMA;
DR   A8Y9G2, RPOC2_LOLPR;  Q9BBS7, RPOC2_LOTJA;  P16025, RPOC2_MAIZE;
DR   B1NWE0, RPOC2_MANES;  P06274, RPOC2_MARPO;  Q9MUS7, RPOC2_MESVI;
DR   B0JGK8, RPOC2_MICAN;  Q09X27, RPOC2_MORIN;  Q09FX1, RPOC2_NANDO;
DR   A4QLS3, RPOC2_NASOF;  Q9TL04, RPOC2_NEPOL;  Q3C1G9, RPOC2_NICSY;
DR   Q33C48, RPOC2_NICTO;  P14564, RPOC2_NOSCO;  B2J1A0, RPOC2_NOSP7;
DR   P22705, RPOC2_NOSS1;  Q6EW58, RPOC2_NYMAL;  P49468, RPOC2_ODOSI;
DR   B2X1Z4, RPOC2_OEDCA;  B0Z4M7, RPOC2_OENAR;  B0Z4W1, RPOC2_OENBI;
DR   Q9MTM3, RPOC2_OENEH;  B0Z545, RPOC2_OENGL;  B0Z5C9, RPOC2_OENPA;
DR   A4QJS3, RPOC2_OLIPU;  Q20EX3, RPOC2_OLTVI;  Q6ENI2, RPOC2_ORYNI;
DR   P0C507, RPOC2_ORYSA;  P0C508, RPOC2_ORYSI;  P0C509, RPOC2_ORYSJ;
DR   Q0P3M4, RPOC2_OSTTA;  Q68S16, RPOC2_PANGI;  B1X3M8, RPOC2_PAUCH;
DR   P12227, RPOC2_PEA  ;  Q06FX1, RPOC2_PELHO;  Q3BAQ2, RPOC2_PHAAO;
DR   A0T0D9, RPOC2_PHATC;  A4GGA7, RPOC2_PHAVU;  P60290, RPOC2_PHYPA;
DR   Q85X62, RPOC2_PINKO;  P41606, RPOC2_PINTH;  Q06GS0, RPOC2_PIPCE;
DR   Q25802, RPOC2_PLAFA;  Q09G56, RPOC2_PLAOC;  Q14FG7, RPOC2_POPAL;
DR   A4GYP8, RPOC2_POPTR;  P51250, RPOC2_PORPU;  Q1XDN7, RPOC2_PORYE;
DR   A3PEX2, RPOC2_PROM0;  A2C4N0, RPOC2_PROM1;  A8G6Y4, RPOC2_PROM2;
DR   A2C6T1, RPOC2_PROM3;  A9BCH4, RPOC2_PROM4;  A2BYK9, RPOC2_PROM5;
DR   Q318Q9, RPOC2_PROM9;  Q7VA30, RPOC2_PROMA;  Q7V5P3, RPOC2_PROMM;
DR   Q7V008, RPOC2_PROMP;  A2BT59, RPOC2_PROMS;  Q46J24, RPOC2_PROMT;
DR   Q3ZJ90, RPOC2_PSEAK;  Q8WI26, RPOC2_PSINU;  A1XGM8, RPOC2_RANMC;
DR   A6MVX2, RPOC2_RHDSA;  Q6L3A5, RPOC2_SACHY;  Q6ENX1, RPOC2_SACOF;
DR   Q1KVX8, RPOC2_SCEOB;  Q589B8, RPOC2_SILLA;  Q9THV5, RPOC2_SINAL;
DR   Q2MIJ7, RPOC2_SOLBU;  Q2MIB0, RPOC2_SOLLC;  Q2VEI6, RPOC2_SOLTU;
DR   Q01923, RPOC2_SORBI;  Q8HVY3, RPOC2_SOYBN;  P11704, RPOC2_SPIOL;
DR   Q32RY2, RPOC2_STAPU;  Q06SF2, RPOC2_STIHE;  Q31N15, RPOC2_SYNE7;
DR   Q2JQT4, RPOC2_SYNJA;  Q2JJ17, RPOC2_SYNJB;  B1XHW1, RPOC2_SYNP2;
DR   Q5MZ21, RPOC2_SYNP6;  A5GNH1, RPOC2_SYNPW;  Q7U8K2, RPOC2_SYNPX;
DR   A5GVF0, RPOC2_SYNR3;  Q0I7L9, RPOC2_SYNS3;  Q3AZA2, RPOC2_SYNS9;
DR   Q3AHX7, RPOC2_SYNSC;  P73334, RPOC2_SYNY3;  A0T0Q9, RPOC2_THAPS;
DR   Q8DL57, RPOC2_THEEB;  P38550, RPOC2_TOBAC;  Q110H3, RPOC2_TRIEI;
DR   Q0ZJ30, RPOC2_VITVI;  B2Y1V7, RPOC2_WELMI;  Q9XPS9, RPOC2_WHEAT;
DR   Q32RG2, RPOC2_ZYGCR;  A9NEL8, RPOC_ACHLI ;  A1TVS9, RPOC_ACIAC ;
DR   Q6FF89, RPOC_ACIAD ;  B2I1Z2, RPOC_ACIBC ;  Q1IHH5, RPOC_ACIBL ;
DR   B0VLZ5, RPOC_ACIBS ;  A3M1G4, RPOC_ACIBT ;  B0VDH9, RPOC_ACIBY ;
DR   A0LRL4, RPOC_ACIC1 ;  A5FZX0, RPOC_ACICJ ;  B9MH46, RPOC_ACIET ;
DR   A1WCM8, RPOC_ACISJ ;  A3N326, RPOC_ACTP2 ;  B3GYV5, RPOC_ACTP7 ;
DR   B0BSF6, RPOC_ACTPJ ;  A6VKC4, RPOC_ACTSZ ;  A0KQA4, RPOC_AERHH ;
DR   A4SHV0, RPOC_AERS4 ;  Q8UE09, RPOC_AGRT5 ;  B2UQY1, RPOC_AKKM8 ;
DR   Q0VSM1, RPOC_ALCBS ;  Q0ABI1, RPOC_ALHEH ;  A6TWI9, RPOC_ALKMQ ;
DR   A8MLD3, RPOC_ALKOO ;  B4RRP8, RPOC_ALTMD ;  B3ETY9, RPOC_AMOA5 ;
DR   Q2II85, RPOC_ANADE ;  A7HCH6, RPOC_ANADF ;  B9KHW2, RPOC_ANAMF ;
DR   Q5PBG3, RPOC_ANAMM ;  Q2GJ69, RPOC_ANAPZ ;  B4UDT1, RPOC_ANASK ;
DR   O67763, RPOC_AQUAE ;  Q9X6Y2, RPOC_AQUPY ;  A8EVZ3, RPOC_ARCB4 ;
DR   Q5P338, RPOC_AROAE ;  A1R8V3, RPOC_ARTAT ;  B8HD15, RPOC_ARTCA ;
DR   A0JZ92, RPOC_ARTS2 ;  Q2NJ16, RPOC_AYWBP ;  A8HTZ1, RPOC_AZOC5 ;
DR   B6YPZ6, RPOC_AZOPC ;  A1KB33, RPOC_AZOSB ;  A7Z0N0, RPOC_BACA2 ;
DR   A0R8H3, RPOC_BACAH ;  P77819, RPOC_BACAN ;  Q73FA3, RPOC_BACC1 ;
DR   A7GK13, RPOC_BACCN ;  Q81J47, RPOC_BACCR ;  Q63H97, RPOC_BACCZ ;
DR   Q5L898, RPOC_BACFN ;  Q64NJ8, RPOC_BACFR ;  Q9Z9M1, RPOC_BACHD ;
DR   Q6HPR5, RPOC_BACHK ;  Q65PB4, RPOC_BACLD ;  A8F977, RPOC_BACP2 ;
DR   Q5WLR9, RPOC_BACSK ;  P37871, RPOC_BACSU ;  Q8A470, RPOC_BACTN ;
DR   A6KYK2, RPOC_BACV8 ;  A9VP70, RPOC_BACWK ;  A1USC9, RPOC_BARBK ;
DR   Q6G3X4, RPOC_BARHE ;  Q6FZM0, RPOC_BARQU ;  A9ISG4, RPOC_BART1 ;
DR   Q1LSX6, RPOC_BAUCH ;  Q6MJ10, RPOC_BDEBA ;  B2IK56, RPOC_BEII9 ;
DR   C5C0K2, RPOC_BEUC1 ;  B8DWJ5, RPOC_BIFA0 ;  A1A316, RPOC_BIFAA ;
DR   B3DTE1, RPOC_BIFLD ;  Q8G515, RPOC_BIFLO ;  Q7VRP8, RPOC_BLOFL ;
DR   Q492C0, RPOC_BLOPB ;  Q2L2L3, RPOC_BORA1 ;  Q0SNB9, RPOC_BORAP ;
DR   Q7WRD8, RPOC_BORBR ;  O51349, RPOC_BORBU ;  B7J1W0, RPOC_BORBZ ;
DR   B5RLU8, RPOC_BORDL ;  Q661N0, RPOC_BORGA ;  B2S091, RPOC_BORHD ;
DR   Q7W2G8, RPOC_BORPA ;  A9IJ22, RPOC_BORPD ;  Q7W0R8, RPOC_BORPE ;
DR   B5RRJ6, RPOC_BORRA ;  A1QZH6, RPOC_BORT9 ;  Q89J75, RPOC_BRAJA ;
DR   A5ELN6, RPOC_BRASB ;  A4YSI2, RPOC_BRASO ;  P77839, RPOC_BROTH ;
DR   B2S686, RPOC_BRUA1 ;  Q2YM16, RPOC_BRUA2 ;  Q57CP9, RPOC_BRUAB ;
DR   A9M5Q8, RPOC_BRUC2 ;  C0RJK9, RPOC_BRUMB ;  Q8YHP7, RPOC_BRUME ;
DR   A5VR14, RPOC_BRUO2 ;  B0CH40, RPOC_BRUSI ;  Q8G070, RPOC_BRUSU ;
DR   P57145, RPOC_BUCAI ;  P41185, RPOC_BUCAP ;  Q89B21, RPOC_BUCBP ;
DR   Q058E6, RPOC_BUCCC ;  B1YRC3, RPOC_BURA4 ;  Q1BRU1, RPOC_BURCA ;
DR   B1JU15, RPOC_BURCC ;  A0K3L8, RPOC_BURCH ;  B4E5B3, RPOC_BURCJ ;
DR   Q0BJ53, RPOC_BURCM ;  A9ADI6, RPOC_BURM1 ;  A3MRU6, RPOC_BURM7 ;
DR   A2S7G7, RPOC_BURM9 ;  Q62GJ7, RPOC_BURMA ;  A1V8B1, RPOC_BURMS ;
DR   A3P0C4, RPOC_BURP0 ;  Q3JMQ4, RPOC_BURP1 ;  A3NEI6, RPOC_BURP6 ;
DR   B2JIH3, RPOC_BURP8 ;  B2T758, RPOC_BURPP ;  Q63Q04, RPOC_BURPS ;
DR   Q39KH4, RPOC_BURS3 ;  Q2SU20, RPOC_BURTA ;  A4JAN3, RPOC_BURVG ;
DR   Q13TG3, RPOC_BURXL ;  A4XI31, RPOC_CALS8 ;  A0RQI4, RPOC_CAMFF ;
DR   A8FKR4, RPOC_CAMJ8 ;  Q9PI30, RPOC_CAMJE ;  A1VYJ5, RPOC_CAMJJ ;
DR   Q5HVY8, RPOC_CAMJR ;  B9KFG8, RPOC_CAMLR ;  Q3A9Q8, RPOC_CARHZ ;
DR   Q05FH9, RPOC_CARRP ;  Q9AAU1, RPOC_CAUCR ;  B0SUP8, RPOC_CAUSK ;
DR   B3PK31, RPOC_CELJU ;  A9WH11, RPOC_CHLAA ;  Q5L5I4, RPOC_CHLAB ;
DR   B8G4U8, RPOC_CHLAD ;  Q3ATP4, RPOC_CHLCH ;  Q822J2, RPOC_CHLCV ;
DR   Q255E5, RPOC_CHLFF ;  B3EER3, RPOC_CHLL2 ;  Q9PK79, RPOC_CHLMU ;
DR   B3QQS1, RPOC_CHLP8 ;  B3EL62, RPOC_CHLPB ;  A1BD24, RPOC_CHLPD ;
DR   Q9Z999, RPOC_CHLPN ;  B9LL90, RPOC_CHLSY ;  B0B7N0, RPOC_CHLT2 ;
DR   B3QYL5, RPOC_CHLT3 ;  Q3KM48, RPOC_CHLTA ;  B0BBU5, RPOC_CHLTB ;
DR   Q8KG14, RPOC_CHLTE ;  O84316, RPOC_CHLTR ;  Q1R0I1, RPOC_CHRSD ;
DR   Q7NQE7, RPOC_CHRVO ;  A8AKT8, RPOC_CITK8 ;  A5CUC6, RPOC_CLAM3 ;
DR   B0RB26, RPOC_CLAMS ;  Q97EH0, RPOC_CLOAB ;  A7FZ76, RPOC_CLOB1 ;
DR   A6LPQ5, RPOC_CLOB8 ;  B2UYA4, RPOC_CLOBA ;  B2TIG9, RPOC_CLOBB ;
DR   A5I7L3, RPOC_CLOBH ;  B1IGG1, RPOC_CLOBK ;  A7GJ81, RPOC_CLOBL ;
DR   B1KSN2, RPOC_CLOBM ;  Q18CF3, RPOC_CLOD6 ;  A5N4P0, RPOC_CLOK5 ;
DR   A0PXT9, RPOC_CLONN ;  Q0TMN9, RPOC_CLOP1 ;  P0C2E8, RPOC_CLOPE ;
DR   A9KJL3, RPOC_CLOPH ;  Q0SQD7, RPOC_CLOPS ;  Q890N5, RPOC_CLOTE ;
DR   A3DIZ5, RPOC_CLOTH ;  Q47UW0, RPOC_COLP3 ;  C3PKN2, RPOC_CORA7 ;
DR   Q6NJF6, RPOC_CORDI ;  Q8FS96, RPOC_COREF ;  A4QBG3, RPOC_CORGB ;
DR   Q8NT25, RPOC_CORGL ;  Q4JT33, RPOC_CORJK ;  C4LL70, RPOC_CORK4 ;
DR   B1VES2, RPOC_CORU7 ;  A9KD37, RPOC_COXBN ;  A9NAL6, RPOC_COXBR ;
DR   Q83ET0, RPOC_COXBU ;  Q0K607, RPOC_CUPNH ;  Q46WD5, RPOC_CUPPJ ;
DR   B3R7T5, RPOC_CUPTR ;  Q85FR6, RPOC_CYAME ;  Q11QA6, RPOC_CYTH3 ;
DR   Q47JA9, RPOC_DECAR ;  Q3Z8V3, RPOC_DEHE1 ;  A5FRK6, RPOC_DEHSB ;
DR   Q3ZX00, RPOC_DEHSC ;  Q1J0P7, RPOC_DEIGD ;  Q9RVW0, RPOC_DEIRA ;
DR   A9BR99, RPOC_DELAS ;  B1I1M9, RPOC_DESAP ;  Q30X04, RPOC_DESDG ;
DR   Q250N9, RPOC_DESHY ;  A8ZV52, RPOC_DESOH ;  Q6AP77, RPOC_DESPS ;
DR   A4J104, RPOC_DESRM ;  Q727C6, RPOC_DESVH ;  A1VAJ5, RPOC_DESVV ;
DR   A5EX69, RPOC_DICNV ;  A8LM41, RPOC_DINSH ;  A7ZUK2, RPOC_ECO24 ;
DR   P0A8T8, RPOC_ECO57 ;  B1XBZ0, RPOC_ECODH ;  A8A787, RPOC_ECOHS ;
DR   A1AIG0, RPOC_ECOK1 ;  Q0TA77, RPOC_ECOL5 ;  Q8FB83, RPOC_ECOL6 ;
DR   B1IUQ9, RPOC_ECOLC ;  P0A8T7, RPOC_ECOLI ;  B1LNU0, RPOC_ECOSM ;
DR   Q1R5V4, RPOC_ECOUT ;  Q3YST4, RPOC_EHRCJ ;  Q2GFP4, RPOC_EHRCR ;
DR   Q5FFD8, RPOC_EHRRG ;  Q5HC04, RPOC_EHRRW ;  B2KEN0, RPOC_ELUMP ;
DR   A4W5A8, RPOC_ENT38 ;  Q82Z41, RPOC_ENTFA ;  A7MQQ8, RPOC_ENTS8 ;
DR   Q6DAM9, RPOC_ERWCT ;  B2VG97, RPOC_ERWT9 ;  Q2N5Q5, RPOC_ERYLH ;
DR   B1YGU3, RPOC_EXIS2 ;  A7HNY1, RPOC_FERNB ;  B0S2E5, RPOC_FINM2 ;
DR   A5FIJ4, RPOC_FLAJ1 ;  A6GYT9, RPOC_FLAPJ ;  Q0RRS9, RPOC_FRAAA ;
DR   B0TX11, RPOC_FRAP2 ;  Q2JFI4, RPOC_FRASC ;  A8LC63, RPOC_FRASN ;
DR   Q14JT4, RPOC_FRAT1 ;  Q2A1M8, RPOC_FRATH ;  B2SFD7, RPOC_FRATM ;
DR   A0Q866, RPOC_FRATN ;  Q0BKC6, RPOC_FRATO ;  Q5NID1, RPOC_FRATT ;
DR   A4IWA0, RPOC_FRATW ;  Q8RHI7, RPOC_FUSNN ;  B5EFP4, RPOC_GEOBB ;
DR   Q5L404, RPOC_GEOKA ;  B3E7S9, RPOC_GEOLS ;  Q39Y12, RPOC_GEOMG ;
DR   B9M6V1, RPOC_GEOSF ;  C6E4R3, RPOC_GEOSM ;  A4IJI2, RPOC_GEOTN ;
DR   A5GAY2, RPOC_GEOUR ;  A9H3S0, RPOC_GLUDA ;  Q5FTX8, RPOC_GLUOX ;
DR   Q0BUQ5, RPOC_GRABC ;  A0M3Y8, RPOC_GRAFK ;  Q7VKL8, RPOC_HAEDU ;
DR   Q4QN34, RPOC_HAEI8 ;  A5U9X9, RPOC_HAEIE ;  A5UH19, RPOC_HAEIG ;
DR   P43739, RPOC_HAEIN ;  Q0I5B8, RPOC_HAES1 ;  B0URZ7, RPOC_HAES2 ;
DR   Q2S906, RPOC_HAHCH ;  A1WVC8, RPOC_HALHL ;  B0TC49, RPOC_HELMI ;
DR   A9B6J1, RPOC_HERA2 ;  A4G9U4, RPOC_HERAR ;  B4U738, RPOC_HYDS0 ;
DR   Q0BYA8, RPOC_HYPNA ;  Q5QWA4, RPOC_IDILO ;  A6T3L2, RPOC_JANMA ;
DR   Q28UX6, RPOC_JANSC ;  A6W5T1, RPOC_KINRD ;  A6TGP1, RPOC_KLEP7 ;
DR   B2GIK0, RPOC_KOCRD ;  Q5FM96, RPOC_LACAC ;  Q03PV0, RPOC_LACBA ;
DR   Q034X1, RPOC_LACC3 ;  B3WAM7, RPOC_LACCB ;  Q1GBM4, RPOC_LACDA ;
DR   Q04C21, RPOC_LACDB ;  B2GDX6, RPOC_LACF3 ;  Q046D1, RPOC_LACGA ;
DR   A8YXJ9, RPOC_LACH4 ;  Q74L94, RPOC_LACJO ;  Q9CEN7, RPOC_LACLA ;
DR   A2RML8, RPOC_LACLM ;  Q02X60, RPOC_LACLS ;  Q88XZ2, RPOC_LACPL ;
DR   A5VLL3, RPOC_LACRD ;  B2G8Y5, RPOC_LACRJ ;  Q1WVA4, RPOC_LACS1 ;
DR   Q38UQ3, RPOC_LACSS ;  Q1MPW9, RPOC_LAWIP ;  Q5X865, RPOC_LEGPA ;
DR   A5IHS0, RPOC_LEGPC ;  Q5ZYP9, RPOC_LEGPH ;  Q5WZL8, RPOC_LEGPL ;
DR   Q6ACX6, RPOC_LEIXX ;  B0SAG0, RPOC_LEPBA ;  Q04QJ0, RPOC_LEPBJ ;
DR   Q054E1, RPOC_LEPBL ;  B0SSI3, RPOC_LEPBP ;  B1Y7H2, RPOC_LEPCP ;
DR   Q72UA7, RPOC_LEPIC ;  Q8F0S3, RPOC_LEPIN ;  B1MVW7, RPOC_LEUCK ;
DR   P94892, RPOC_LEUMM ;  P94899, RPOC_LEUPS ;  P77882, RPOC_LISGR ;
DR   P77879, RPOC_LISIN ;  Q724E9, RPOC_LISMF ;  Q8YA96, RPOC_LISMO ;
DR   A0AF64, RPOC_LISW6 ;  B1HMZ5, RPOC_LYSSC ;  Q2W2I2, RPOC_MAGSA ;
DR   A0L5W7, RPOC_MAGSM ;  Q65W40, RPOC_MANSM ;  A1TYJ1, RPOC_MARAV ;
DR   Q0ANP4, RPOC_MARMM ;  A6W398, RPOC_MARMS ;  Q6F0L8, RPOC_MESFL ;
DR   Q11HB4, RPOC_MESSB ;  B7KN46, RPOC_METC4 ;  Q60A05, RPOC_METCA ;
DR   A9W8N9, RPOC_METEP ;  Q1H4P3, RPOC_METFK ;  B3E164, RPOC_METI4 ;
DR   B8IS79, RPOC_METNO ;  B1ZGS1, RPOC_METPB ;  A2SLG4, RPOC_METPP ;
DR   B1LY42, RPOC_METRJ ;  B0UHX5, RPOC_METS4 ;  C5CC70, RPOC_MICLC ;
DR   Q2RFP0, RPOC_MOOTA ;  A0QL48, RPOC_MYCA1 ;  B3PM77, RPOC_MYCA5 ;
DR   B1MH61, RPOC_MYCA9 ;  A5IZ52, RPOC_MYCAP ;  P0A675, RPOC_MYCBO ;
DR   A1KGE8, RPOC_MYCBP ;  C1AL01, RPOC_MYCBT ;  Q2ST47, RPOC_MYCCT ;
DR   P47716, RPOC_MYCGA ;  P47582, RPOC_MYCGE ;  A4T1P3, RPOC_MYCGI ;
DR   Q5ZZS2, RPOC_MYCH2 ;  Q4A7B0, RPOC_MYCH7 ;  Q4A970, RPOC_MYCHJ ;
DR   B8ZSC6, RPOC_MYCLB ;  P30761, RPOC_MYCLE ;  B2HSJ4, RPOC_MYCMM ;
DR   Q6KI08, RPOC_MYCMO ;  Q6MRX5, RPOC_MYCMS ;  Q73SE3, RPOC_MYCPA ;
DR   Q8EWX0, RPOC_MYCPE ;  P75271, RPOC_MYCPN ;  Q98Q24, RPOC_MYCPU ;
DR   A0QS66, RPOC_MYCS2 ;  Q4A5S8, RPOC_MYCS5 ;  A3PV79, RPOC_MYCSJ ;
DR   A1UBJ4, RPOC_MYCSK ;  Q1BDE9, RPOC_MYCSS ;  A5U053, RPOC_MYCTA ;
DR   P0A674, RPOC_MYCTU ;  A0PM25, RPOC_MYCUA ;  A1T4J3, RPOC_MYCVP ;
DR   Q1D7U2, RPOC_MYXXD ;  B2A4D2, RPOC_NATTJ ;  Q5F5R6, RPOC_NEIG1 ;
DR   B4RQW3, RPOC_NEIG2 ;  A9M3X3, RPOC_NEIM0 ;  Q9JX03, RPOC_NEIMA ;
DR   Q9K1J1, RPOC_NEIMB ;  A1KRG7, RPOC_NEIMF ;  Q2GD91, RPOC_NEOSM ;
DR   Q0AF54, RPOC_NITEC ;  Q82T76, RPOC_NITEU ;  Q1QN43, RPOC_NITHX ;
DR   Q2YB04, RPOC_NITMU ;  Q3J8Q8, RPOC_NITOC ;  A6Q1M4, RPOC_NITSB ;
DR   Q3SSX9, RPOC_NITWN ;  Q5YPE1, RPOC_NOCFA ;  A1SEK2, RPOC_NOCSJ ;
DR   Q2GCD8, RPOC_NOVAD ;  Q8ETY7, RPOC_OCEIH ;  A6X0B0, RPOC_OCHA4 ;
DR   Q04E86, RPOC_OENOB ;  P95405, RPOC_OENOE ;  B6JES1, RPOC_OLICO ;
DR   Q6YQW2, RPOC_ONYPE ;  B1ZPB7, RPOC_OPITP ;  A5CC92, RPOC_ORITB ;
DR   B3CV54, RPOC_ORITI ;  A6LE80, RPOC_PARD8 ;  A1B017, RPOC_PARDP ;
DR   A7HWQ5, RPOC_PARL1 ;  Q6MDM0, RPOC_PARUW ;  Q9CK92, RPOC_PASMU ;
DR   P77917, RPOC_PEDAC ;  Q03EB0, RPOC_PEDPA ;  Q3A6Q3, RPOC_PELCD ;
DR   Q3B1H8, RPOC_PELLD ;  B4SG10, RPOC_PELPB ;  A1ALT5, RPOC_PELPD ;
DR   A5D5I3, RPOC_PELTS ;  Q4FLL3, RPOC_PELUB ;  A9BF32, RPOC_PETMO ;
DR   Q7N9A3, RPOC_PHOLL ;  Q6LLW3, RPOC_PHOPR ;  A1VTF7, RPOC_POLNA ;
DR   B1XSP4, RPOC_POLNS ;  Q123G4, RPOC_POLSJ ;  A4SUV5, RPOC_POLSQ ;
DR   O33431, RPOC_PORCN ;  B2RL44, RPOC_PORG3 ;  Q7MX26, RPOC_PORGI ;
DR   B4S498, RPOC_PROA2 ;  Q6A6K7, RPOC_PROAC ;  A4SGK5, RPOC_PROVI ;
DR   Q48D30, RPOC_PSE14 ;  Q15YB0, RPOC_PSEA6 ;  A6UZI2, RPOC_PSEA7 ;
DR   Q02T86, RPOC_PSEAB ;  Q9HWC9, RPOC_PSEAE ;  Q1IFX2, RPOC_PSEE4 ;
DR   Q4K527, RPOC_PSEF5 ;  C3K2Y2, RPOC_PSEFS ;  Q3ILP8, RPOC_PSEHT ;
DR   A4XZ96, RPOC_PSEMY ;  A5VXP1, RPOC_PSEP1 ;  Q3K5Y2, RPOC_PSEPF ;
DR   B0KK61, RPOC_PSEPG ;  Q88QP1, RPOC_PSEPK ;  P19176, RPOC_PSEPU ;
DR   B1JDX0, RPOC_PSEPW ;  Q889X7, RPOC_PSESM ;  Q4ZMN8, RPOC_PSEU2 ;
DR   A4VHM4, RPOC_PSEU5 ;  Q4FQH4, RPOC_PSYA2 ;  Q1Q8Q0, RPOC_PSYCK ;
DR   A1T064, RPOC_PSYIN ;  A5WH34, RPOC_PSYWF ;  Q1LI21, RPOC_RALME ;
DR   Q8XUZ9, RPOC_RALSO ;  A9WSX9, RPOC_RENSM ;  B3PW60, RPOC_RHIE6 ;
DR   Q2K9M3, RPOC_RHIEC ;  Q1MIE8, RPOC_RHIL3 ;  Q98N65, RPOC_RHILO ;
DR   Q92QH6, RPOC_RHIME ;  Q7URW4, RPOC_RHOBA ;  B6IRP7, RPOC_RHOCS ;
DR   C0ZVQ7, RPOC_RHOE4 ;  Q21SF8, RPOC_RHOFD ;  C1AYV8, RPOC_RHOOB ;
DR   Q2IXR9, RPOC_RHOP2 ;  Q07KK8, RPOC_RHOP5 ;  Q6N4S0, RPOC_RHOPA ;
DR   Q211D9, RPOC_RHOPB ;  Q134R9, RPOC_RHOPS ;  B3QBZ9, RPOC_RHOPT ;
DR   Q2RQV4, RPOC_RHORT ;  A3PGJ0, RPOC_RHOS1 ;  Q3J5S9, RPOC_RHOS4 ;
DR   A4WVL5, RPOC_RHOS5 ;  Q0SFB4, RPOC_RHOSR ;  A8GMA8, RPOC_RICAH ;
DR   A8GV25, RPOC_RICB8 ;  Q1RHD1, RPOC_RICBR ;  A8EXK9, RPOC_RICCK ;
DR   Q9RH40, RPOC_RICCN ;  Q4UKD5, RPOC_RICFE ;  A8F0P8, RPOC_RICM5 ;
DR   Q9ZE20, RPOC_RICPR ;  B0BWB0, RPOC_RICRO ;  A8GQW5, RPOC_RICRS ;
DR   Q68XM7, RPOC_RICTY ;  A7NJM0, RPOC_ROSCS ;  Q160X8, RPOC_ROSDO ;
DR   A5USR6, RPOC_ROSS1 ;  Q1AU23, RPOC_RUBXD ;  A1AX74, RPOC_RUTMC ;
DR   Q21M92, RPOC_SACD2 ;  A4FPP2, RPOC_SACEN ;  A8M538, RPOC_SALAI ;
DR   A9MHE9, RPOC_SALAR ;  Q57H68, RPOC_SALCH ;  Q5PK92, RPOC_SALPA ;
DR   A9N0J5, RPOC_SALPB ;  Q2S1Q6, RPOC_SALRD ;  P0A2R5, RPOC_SALTI ;
DR   A4XBQ5, RPOC_SALTO ;  P0A2R4, RPOC_SALTY ;  A8G8E8, RPOC_SERP5 ;
DR   A1S212, RPOC_SHEAM ;  B8EBL1, RPOC_SHEB2 ;  A6WHS2, RPOC_SHEB8 ;
DR   A9KW96, RPOC_SHEB9 ;  Q12SW5, RPOC_SHEDO ;  Q089R0, RPOC_SHEFN ;
DR   B0TM18, RPOC_SHEHH ;  A3Q976, RPOC_SHELP ;  Q8EK73, RPOC_SHEON ;
DR   A8GYX0, RPOC_SHEPA ;  A4YBY9, RPOC_SHEPC ;  B8CNC6, RPOC_SHEPW ;
DR   A0KRL8, RPOC_SHESA ;  A8G1F4, RPOC_SHESH ;  Q0HNU3, RPOC_SHESM ;
DR   Q0I0B1, RPOC_SHESR ;  A1REA8, RPOC_SHESW ;  Q9KW13, RPOC_SHEVI ;
DR   B1KMY9, RPOC_SHEWM ;  B2TWH4, RPOC_SHIB3 ;  Q31U09, RPOC_SHIBS ;
DR   Q32AG0, RPOC_SHIDS ;  Q0SY12, RPOC_SHIF8 ;  P0A8T9, RPOC_SHIFL ;
DR   Q3YUZ6, RPOC_SHISS ;  Q5LMQ6, RPOC_SILPO ;  Q1GK48, RPOC_SILST ;
DR   A6U852, RPOC_SINMW ;  Q2NWR5, RPOC_SODGM ;  Q01VB2, RPOC_SOLUE ;
DR   A9GRB4, RPOC_SORC5 ;  Q1GT24, RPOC_SPHAL ;  A5VBZ7, RPOC_SPHWW ;
DR   Q2FJ97, RPOC_STAA3 ;  Q2G0N5, RPOC_STAA8 ;  Q2YSB8, RPOC_STAAB ;
DR   Q5HID2, RPOC_STAAC ;  P60284, RPOC_STAAM ;  P60285, RPOC_STAAN ;
DR   Q6GJC5, RPOC_STAAR ;  Q6GBU4, RPOC_STAAS ;  P0C1T4, RPOC_STAAU ;
DR   P60286, RPOC_STAAW ;  Q5HRK9, RPOC_STAEQ ;  Q8CQ83, RPOC_STAES ;
DR   Q4L3K4, RPOC_STAHJ ;  Q49V53, RPOC_STAS1 ;  Q3K3L1, RPOC_STRA1 ;
DR   Q8E7J7, RPOC_STRA3 ;  Q8E238, RPOC_STRA5 ;  Q82DQ4, RPOC_STRAW ;
DR   Q8CJT1, RPOC_STRCO ;  C0M7R5, RPOC_STRE4 ;  A8AZI2, RPOC_STRGC ;
DR   B1W441, RPOC_STRGG ;  B2FQ39, RPOC_STRMK ;  Q8DS47, RPOC_STRMU ;
DR   P0C0E0, RPOC_STRP1 ;  Q04IK7, RPOC_STRP2 ;  P0DF32, RPOC_STRP3 ;
DR   B5E2F2, RPOC_STRP4 ;  Q5XE96, RPOC_STRP6 ;  C1CA05, RPOC_STRP7 ;
DR   Q8P2Y2, RPOC_STRP8 ;  Q1JE19, RPOC_STRPB ;  Q1JNX6, RPOC_STRPC ;
DR   Q1JJ22, RPOC_STRPD ;  Q1J8X0, RPOC_STRPF ;  A2RC52, RPOC_STRPG ;
DR   B1I8R3, RPOC_STRPI ;  B8ZNW6, RPOC_STRPJ ;  Q48VR0, RPOC_STRPM ;
DR   Q97NQ8, RPOC_STRPN ;  P0DF33, RPOC_STRPQ ;  B2IM39, RPOC_STRPS ;
DR   P0C0D9, RPOC_STRPY ;  Q8DNF1, RPOC_STRR6 ;  A4VYU4, RPOC_STRS2 ;
DR   C0MEE4, RPOC_STRS7 ;  A3CKD4, RPOC_STRSV ;  A4VSK3, RPOC_STRSY ;
DR   Q5LXV4, RPOC_STRT1 ;  Q5M2F6, RPOC_STRT2 ;  Q03IK3, RPOC_STRTD ;
DR   B9DSZ6, RPOC_STRU0 ;  C1CGP3, RPOC_STRZJ ;  C1CMQ7, RPOC_STRZP ;
DR   C1CTL3, RPOC_STRZT ;  Q30TP6, RPOC_SULDN ;  A8Z5T2, RPOC_SULMW ;
DR   A6Q6I3, RPOC_SULNB ;  B2V7L9, RPOC_SULSY ;  Q67JT4, RPOC_SYMTH ;
DR   Q2LQ86, RPOC_SYNAS ;  A0LII5, RPOC_SYNFM ;  Q0AUH3, RPOC_SYNWW ;
DR   B7ICR2, RPOC_THEAB ;  Q9KWU6, RPOC_THEAQ ;  Q47LI6, RPOC_THEFY ;
DR   A8F4G1, RPOC_THELT ;  A6LKB7, RPOC_THEM4 ;  P36252, RPOC_THEMA ;
DR   B9KBJ4, RPOC_THENN ;  A5IJW2, RPOC_THEP1 ;  B0KCJ3, RPOC_THEP3 ;
DR   B0K5G9, RPOC_THEPX ;  B1L934, RPOC_THESQ ;  Q72HM6, RPOC_THET2 ;
DR   Q8RQE8, RPOC_THET8 ;  Q8R7U7, RPOC_THETN ;  B5YFV7, RPOC_THEYD ;
DR   Q31IY8, RPOC_THICR ;  Q3SLQ5, RPOC_THIDA ;  C4LBV1, RPOC_TOLAT ;
DR   Q73JJ8, RPOC_TREDE ;  O83270, RPOC_TREPA ;  B2S2I9, RPOC_TREPS ;
DR   Q820D9, RPOC_TROW8 ;  Q820D6, RPOC_TROWT ;  B1GZ76, RPOC_UNCTG ;
DR   B1AIH6, RPOC_UREP2 ;  Q9PQV5, RPOC_UREPA ;  B5ZAZ4, RPOC_UREU1 ;
DR   C5CKF4, RPOC_VARPS ;  A1WK56, RPOC_VEREI ;  A5CW24, RPOC_VESOH ;
DR   A5F3P6, RPOC_VIBC3 ;  Q9KV29, RPOC_VIBCH ;  Q5E239, RPOC_VIBF1 ;
DR   A7MXF0, RPOC_VIBHB ;  Q87KQ5, RPOC_VIBPA ;  Q8DD19, RPOC_VIBVU ;
DR   Q7MGS0, RPOC_VIBVY ;  P96177, RPOC_WEIHE ;  P96178, RPOC_WEIPA ;
DR   Q8D232, RPOC_WIGBR ;  Q8PNS9, RPOC_XANAC ;  Q3BWZ0, RPOC_XANC5 ;
DR   Q4URD3, RPOC_XANC8 ;  B0RU88, RPOC_XANCB ;  Q8PC55, RPOC_XANCP ;
DR   Q2NZX9, RPOC_XANOM ;  B2SQQ2, RPOC_XANOP ;  Q8KTH8, RPOC_XANOR ;
DR   A7IKQ1, RPOC_XANP2 ;  B2IA67, RPOC_XYLF2 ;  Q9PA87, RPOC_XYLFA ;
DR   B0U5X6, RPOC_XYLFM ;  Q87A33, RPOC_XYLFT ;  A1JII1, RPOC_YERE8 ;
DR   A7FNI2, RPOC_YERP3 ;  Q1C1U2, RPOC_YERPA ;  B2K114, RPOC_YERPB ;
DR   Q8D1H3, RPOC_YERPE ;  A9R0H9, RPOC_YERPG ;  Q1CN77, RPOC_YERPN ;
DR   A4TS28, RPOC_YERPP ;  Q66FQ1, RPOC_YERPS ;  B1JJK0, RPOC_YERPY ;
DR   Q5NPK4, RPOC_ZYMMO ;  Q9YB53, RPOD_AERPE ;  O28002, RPOD_ARCFU ;
DR   Q00813, RPOD_HALMA ;  B0R4Y2, RPOD_HALS3 ;  Q9HQJ4, RPOD_HALSA ;
DR   P0CG28, RPOD_METAC ;  Q57648, RPOD_METJA ;  Q8TVB8, RPOD_METKA ;
DR   Q8PV16, RPOD_METMA ;  A5UN55, RPOD_METS3 ;  Q2NFZ6, RPOD_METST ;
DR   O26144, RPOD_METTH ;  Q3IQT6, RPOD_NATPD ;  Q6KZP5, RPOD_PICTO ;
DR   Q9V198, RPOD_PYRAB ;  Q8ZYQ3, RPOD_PYRAE ;  A4WNA4, RPOD_PYRAR ;
DR   A3MXZ5, RPOD_PYRCJ ;  Q8U0E4, RPOD_PYRFU ;  O59303, RPOD_PYRHO ;
DR   A1RSE3, RPOD_PYRIL ;  Q5JJF4, RPOD_PYRKO ;  P39471, RPOD_SULAC ;
DR   C3N054, RPOD_SULIA ;  C4KJ93, RPOD_SULIK ;  C3MJP7, RPOD_SULIL ;
DR   C3MZ05, RPOD_SULIM ;  C3NMQ0, RPOD_SULIN ;  C3N8R8, RPOD_SULIY ;
DR   P95989, RPOD_SULSO ;  Q96YW0, RPOD_SULTO ;  Q9HJD9, RPOD_THEAC ;
DR   B1YC30, RPOD_THENV ;  Q97B93, RPOD_THEVO ;  Q57840, RPOE1_METJA;
DR   Q57839, RPOE2_METJA;  P39466, RPOE_SULAC ;  Q9YAT3, RPOH_AERPE ;
DR   O28394, RPOH_ARCFU ;  B0R8D7, RPOH_HALS3 ;  P0CX06, RPOH_HALSA ;
DR   A2BN32, RPOH_HYPBU ;  A6UV53, RPOH_META3 ;  Q8TRB4, RPOH_METAC ;
DR   Q464Y4, RPOH_METBF ;  Q12WS3, RPOH_METBU ;  Q58443, RPOH_METJA ;
DR   Q8TXI5, RPOH_METKA ;  A2SSM7, RPOH_METLZ ;  A4FWF9, RPOH_METM5 ;
DR   A9A9V3, RPOH_METM6 ;  A6VGU6, RPOH_METM7 ;  Q8PUQ8, RPOH_METMA ;
DR   P61519, RPOH_METMP ;  A4YCQ7, RPOH_METS5 ;  Q2NEK1, RPOH_METST ;
DR   O27122, RPOH_METTH ;  A0B555, RPOH_METTP ;  P41559, RPOH_METVS ;
DR   A9A458, RPOH_NITMS ;  Q9V116, RPOH_PYRAB ;  Q8ZYR0, RPOH_PYRAE ;
DR   Q8U0M2, RPOH_PYRFU ;  O74019, RPOH_PYRHO ;  Q5JE31, RPOH_PYRKO ;
DR   A3DMP2, RPOH_STAMF ;  P11521, RPOH_SULAC ;  C3MZM6, RPOH_SULIA ;
DR   C4KIV6, RPOH_SULIK ;  C3MRK1, RPOH_SULIL ;  C3MY97, RPOH_SULIM ;
DR   C3NFS5, RPOH_SULIN ;  C3N7P8, RPOH_SULIY ;  Q980Q9, RPOH_SULSO ;
DR   Q976A3, RPOH_SULTO ;  Q03588, RPOH_THEAC ;  P31815, RPOH_THECE ;
DR   C5A210, RPOH_THEGJ ;  B6YT14, RPOH_THEON ;  A1RWW7, RPOH_THEPD ;
DR   C6A1F8, RPOH_THESM ;  Q979F2, RPOH_THEVO ;  Q58785, RPOI_METJA ;
DR   Q9YDJ9, RPOK_AERPE ;  O29134, RPOK_ARCFU ;  B9LPW5, RPOK_HALLT ;
DR   P29200, RPOK_HALMA ;  B0R4Y7, RPOK_HALS3 ;  Q9HQJ0, RPOK_HALSA ;
DR   Q8TT40, RPOK_METAC ;  Q57650, RPOK_METJA ;  A2SSV2, RPOK_METLZ ;
DR   Q8PW42, RPOK_METMA ;  O26148, RPOK_METTH ;  A0B6E6, RPOK_METTP ;
DR   Q6L1M4, RPOK_PICTO ;  P62014, RPOK_PYRAB ;  Q8ZTF9, RPOK_PYRAE ;
DR   Q8U0E8, RPOK_PYRFU ;  P62015, RPOK_PYRHO ;  Q5JJD0, RPOK_PYRKO ;
DR   P39463, RPOK_SULAC ;  C3N5H2, RPOK_SULIA ;  C4KH38, RPOK_SULIK ;
DR   C3MUV8, RPOK_SULIM ;  Q97ZJ9, RPOK_SULSO ;  Q972B1, RPOK_SULTO ;
DR   Q9HJ14, RPOK_THEAC ;  C5A244, RPOK_THEGJ ;  B6YSQ8, RPOK_THEON ;
DR   A1RWX0, RPOK_THEPD ;  P58232, RPOK_THEVO ;  Q9YEZ1, RPOL_AERPE ;
DR   O30032, RPOL_ARCFU ;  P18147, RPOL_BPK11 ;  P06221, RPOL_BPSP6 ;
DR   P07659, RPOL_BPT3  ;  P00573, RPOL_BPT7  ;  B9LTT8, RPOL_HALLT ;
DR   Q5V2C7, RPOL_HALMA ;  B0R4B1, RPOL_HALS3 ;  Q9HR53, RPOL_HALSA ;
DR   Q18JI2, RPOL_HALWD ;  P05472, RPOL_KLULA ;  B1L7Q7, RPOL_KORCO ;
DR   Q8TSS4, RPOL_METAC ;  Q46C10, RPOL_METBF ;  Q12W27, RPOL_METBU ;
DR   Q57832, RPOL_METJA ;  Q8TZ81, RPOL_METKA ;  A4FZS6, RPOL_METM5 ;
DR   A9A836, RPOL_METM6 ;  A6VIQ1, RPOL_METM7 ;  Q8PVT0, RPOL_METMA ;
DR   Q6M0K9, RPOL_METMP ;  A4YHV0, RPOL_METS5 ;  O27372, RPOL_METTH ;
DR   A0B533, RPOL_METTP ;  A6URP9, RPOL_METVS ;  Q74MN9, RPOL_NANEQ ;
DR   Q3INY0, RPOL_NATPD ;  Q6L204, RPOL_PICTO ;  Q9V2M4, RPOL_PYRAB ;
DR   Q8ZW46, RPOL_PYRAE ;  Q8U4N1, RPOL_PYRFU ;  P57671, RPOL_PYRHO ;
DR   Q5JE88, RPOL_PYRKO ;  P46217, RPOL_SULAC ;  C3MZG6, RPOL_SULIA ;
DR   C4KIP6, RPOL_SULIK ;  C3MRD1, RPOL_SULIL ;  C3MXM0, RPOL_SULIM ;
DR   C3NFY8, RPOL_SULIN ;  C3N7I8, RPOL_SULIY ;  Q980K0, RPOL_SULSO ;
DR   Q96YA7, RPOL_SULTO ;  Q9HIC5, RPOL_THEAC ;  C5A5J3, RPOL_THEGJ ;
DR   B6YTH7, RPOL_THEON ;  C6A1R5, RPOL_THESM ;  Q978F5, RPOL_THEVO ;
DR   Q0W8P1, RPOL_UNCMA ;  O29033, RPOM_ARCFU ;  O00411, RPOM_HUMAN ;
DR   Q58548, RPOM_METJA ;  O27369, RPOM_METTH ;  Q8BKF1, RPOM_MOUSE ;
DR   P38671, RPOM_NEUCR ;  O13993, RPOM_SCHPO ;  Q07271, RPOM_SULAC ;
DR   Q56254, RPOM_THECE ;  P13433, RPOM_YEAST ;  Q9YB47, RPON_AERPE ;
DR   O29135, RPON_ARCFU ;  A8M9S4, RPON_CALMQ ;  B9LPW4, RPON_HALLT ;
DR   P29199, RPON_HALMA ;  B0R4Y6, RPON_HALS3 ;  Q9HQJ1, RPON_HALSA ;
DR   Q18G60, RPON_HALWD ;  A2BK83, RPON_HYPBU ;  Q8TT41, RPON_METAC ;
DR   A7IAH1, RPON_METB6 ;  Q46CK8, RPON_METBF ;  Q12TI4, RPON_METBU ;
DR   Q2FTN7, RPON_METHJ ;  Q57649, RPON_METJA ;  Q8TVB4, RPON_METKA ;
DR   A2SSV3, RPON_METLZ ;  A4FWK8, RPON_METM5 ;  A9A9Y7, RPON_METM6 ;
DR   A6VGR3, RPON_METM7 ;  Q8PW43, RPON_METMA ;  A3CWI3, RPON_METMJ ;
DR   Q6LXM4, RPON_METMP ;  B8GEG1, RPON_METPE ;  A4YIM8, RPON_METS5 ;
DR   O26147, RPON_METTH ;  A0B6E7, RPON_METTP ;  A6UPX1, RPON_METVS ;
DR   Q74MB5, RPON_NANEQ ;  Q3IQT2, RPON_NATPD ;  Q6L292, RPON_PICTO ;
DR   P60291, RPON_PYRAB ;  Q8ZYP9, RPON_PYRAE ;  A4WNA8, RPON_PYRAR ;
DR   A3MXZ9, RPON_PYRCJ ;  P60292, RPON_PYRFU ;  O59298, RPON_PYRHO ;
DR   A1RSD9, RPON_PYRIL ;  Q5JJC9, RPON_PYRKO ;  A3DMR0, RPON_STAMF ;
DR   P39472, RPON_SULAC ;  C3N058, RPON_SULIA ;  C4KJ97, RPON_SULIK ;
DR   C3MJQ1, RPON_SULIL ;  C3MZ09, RPON_SULIM ;  C3NMP6, RPON_SULIN ;
DR   C3N8S2, RPON_SULIY ;  Q980Z8, RPON_SULSO ;  Q96YW4, RPON_SULTO ;
DR   Q9HL09, RPON_THEAC ;  B1YC34, RPON_THENV ;  B6YSQ7, RPON_THEON ;
DR   Q979K0, RPON_THEVO ;  Q0W8C7, RPON_UNCMA ;  P33539, RPOP_AGABT ;
DR   O30180, RPOP_ARCFU ;  P22372, RPOP_CLAPU ;  O03685, RPOP_GELSP ;
DR   B9LTN3, RPOP_HALLT ;  Q5V1M2, RPOP_HALMA ;  B0R2Y0, RPOP_HALS3 ;
DR   Q9HSG9, RPOP_HALSA ;  Q18KN3, RPOP_HALWD ;  P10581, RPOP_MAIZE ;
DR   P61933, RPOP_METAC ;  Q469M0, RPOP_METBF ;  Q12ZB4, RPOP_METBU ;
DR   P59283, RPOP_METJA ;  Q8TYC4, RPOP_METKA ;  P61934, RPOP_METMA ;
DR   A0B8W0, RPOP_METTP ;  Q3IMF0, RPOP_NATPD ;  P33540, RPOP_NEUCS ;
DR   P33541, RPOP_NEUIN ;  Q01521, RPOP_PODAS ;  Q9V201, RPOP_PYRAB ;
DR   Q8ZVI9, RPOP_PYRAE ;  A4WLV9, RPOP_PYRAR ;  A3MWM4, RPOP_PYRCJ ;
DR   Q8TZI3, RPOP_PYRFU ;  O74105, RPOP_PYRHO ;  Q5JDM8, RPOP_PYRKO ;
DR   Q4JAE8, RPOP_SULAC ;  C3N6M6, RPOP_SULIA ;  C4KI98, RPOP_SULIK ;
DR   C3MQX1, RPOP_SULIL ;  C3MWV9, RPOP_SULIM ;  C3NGJ6, RPOP_SULIN ;
DR   C3N740, RPOP_SULIY ;  Q97ZX7, RPOP_SULSO ;  Q975R9, RPOP_SULTO ;
DR   B1Y9C5, RPOP_THENV ;  B6YTZ7, RPOP_THEON ;  Q0W2Y5, RPOP_UNCMA ;
DR   P92969, RPOT1_ARATH;  Q93Y94, RPOT1_NICSY;  Q9LFV6, RPOT2_ARATH;
DR   Q8VWF8, RPOT2_NICSY;  O24600, RPOT3_ARATH;  P69242, RPOT3_NICSY;
DR   B0C118, RPOZ_ACAM1 ;  A1TT47, RPOZ_ACIAC ;  Q6F7G9, RPOZ_ACIAD ;
DR   B7GVQ9, RPOZ_ACIB3 ;  B7IAU2, RPOZ_ACIB5 ;  B2HZW5, RPOZ_ACIBC ;
DR   B0VQ51, RPOZ_ACIBS ;  A3M9H4, RPOZ_ACIBT ;  B0V8M2, RPOZ_ACIBY ;
DR   A0LUF4, RPOZ_ACIC1 ;  A5FVX2, RPOZ_ACICJ ;  B9MEK5, RPOZ_ACIET ;
DR   B7J583, RPOZ_ACIF2 ;  B5EN39, RPOZ_ACIF5 ;  A1W4L3, RPOZ_ACISJ ;
DR   A3N3C2, RPOZ_ACTP2 ;  B3GZ78, RPOZ_ACTP7 ;  B0BSZ8, RPOZ_ACTPJ ;
DR   A6VN44, RPOZ_ACTSZ ;  A0KR23, RPOZ_AERHH ;  A4SH73, RPOZ_AERS4 ;
DR   B9JC68, RPOZ_AGRRK ;  Q8UGK8, RPOZ_AGRT5 ;  B9JUN3, RPOZ_AGRVS ;
DR   Q0VT95, RPOZ_ALCBS ;  Q0A5V4, RPOZ_ALHEH ;  B6EPJ3, RPOZ_ALISL ;
DR   A6TRX1, RPOZ_ALKMQ ;  A8MH81, RPOZ_ALKOO ;  B4S2X2, RPOZ_ALTMD ;
DR   B8J6T5, RPOZ_ANAD2 ;  Q2IFJ5, RPOZ_ANADE ;  A7HGP4, RPOZ_ANADF ;
DR   B9KI83, RPOZ_ANAMF ;  Q5PB40, RPOZ_ANAMM ;  Q2GKJ2, RPOZ_ANAPZ ;
DR   B4UD71, RPOZ_ANASK ;  Q3MBJ9, RPOZ_ANAVT ;  O66570, RPOZ_AQUAE ;
DR   Q5P3L9, RPOZ_AROAE ;  A8I0F9, RPOZ_AZOC5 ;  A1KCL2, RPOZ_AZOSB ;
DR   C1DI45, RPOZ_AZOVD ;  A7Z4I9, RPOZ_BACA2 ;  C3P641, RPOZ_BACAA ;
DR   C3L757, RPOZ_BACAC ;  A0RHP3, RPOZ_BACAH ;  Q81WG8, RPOZ_BACAN ;
DR   B7JJV7, RPOZ_BACC0 ;  B7IUM9, RPOZ_BACC2 ;  C1EP94, RPOZ_BACC3 ;
DR   B7H6K7, RPOZ_BACC4 ;  B7HLK3, RPOZ_BACC7 ;  A7GRK0, RPOZ_BACCN ;
DR   B9IVU6, RPOZ_BACCQ ;  Q819T7, RPOZ_BACCR ;  Q636F6, RPOZ_BACCZ ;
DR   Q9K9Y3, RPOZ_BACHD ;  Q6HEU5, RPOZ_BACHK ;  Q65JS9, RPOZ_BACLD ;
DR   A8FD34, RPOZ_BACP2 ;  Q5WFK4, RPOZ_BACSK ;  O35011, RPOZ_BACSU ;
DR   A9VTA8, RPOZ_BACWK ;  A1US30, RPOZ_BARBK ;  Q6G465, RPOZ_BARHE ;
DR   Q6G088, RPOZ_BARQU ;  A9IRL2, RPOZ_BART1 ;  Q1LTY2, RPOZ_BAUCH ;
DR   Q6MMQ7, RPOZ_BDEBA ;  B2IIA1, RPOZ_BEII9 ;  C5C692, RPOZ_BEUC1 ;
DR   B8DTW7, RPOZ_BIFA0 ;  A1A0T8, RPOZ_BIFAA ;  B3DRM7, RPOZ_BIFLD ;
DR   Q8G3H3, RPOZ_BIFLO ;  B7GUQ0, RPOZ_BIFLS ;  Q491W4, RPOZ_BLOPB ;
DR   Q2L066, RPOZ_BORA1 ;  Q7WI79, RPOZ_BORBR ;  Q7W6B1, RPOZ_BORPA ;
DR   A9ILJ1, RPOZ_BORPD ;  Q7VXZ4, RPOZ_BORPE ;  Q9RH70, RPOZ_BRAJA ;
DR   A5EKM2, RPOZ_BRASB ;  A4YWD3, RPOZ_BRASO ;  C0ZG01, RPOZ_BREBN ;
DR   B2SAC9, RPOZ_BRUA1 ;  Q2YN12, RPOZ_BRUA2 ;  Q57E91, RPOZ_BRUAB ;
DR   A9MA26, RPOZ_BRUC2 ;  C0RHZ3, RPOZ_BRUMB ;  Q8YG64, RPOZ_BRUME ;
DR   A5VPI8, RPOZ_BRUO2 ;  B0CKX7, RPOZ_BRUSI ;  Q8G1Q6, RPOZ_BRUSU ;
DR   B1YUY0, RPOZ_BURA4 ;  Q1BY72, RPOZ_BURCA ;  B1JXM5, RPOZ_BURCC ;
DR   A0K5H6, RPOZ_BURCH ;  B4EBP5, RPOZ_BURCJ ;  Q0BHF4, RPOZ_BURCM ;
DR   A9AEQ4, RPOZ_BURM1 ;  A3MML1, RPOZ_BURM7 ;  A2S9I5, RPOZ_BURM9 ;
DR   Q62I01, RPOZ_BURMA ;  A1V1Q6, RPOZ_BURMS ;  A3NY34, RPOZ_BURP0 ;
DR   Q3JPT0, RPOZ_BURP1 ;  A3NC92, RPOZ_BURP6 ;  B2JEI3, RPOZ_BURP8 ;
DR   B2T6B2, RPOZ_BURPP ;  Q63RV8, RPOZ_BURPS ;  Q39IL1, RPOZ_BURS3 ;
DR   Q2SY71, RPOZ_BURTA ;  A4JCC5, RPOZ_BURVG ;  Q13V50, RPOZ_BURXL ;
DR   A7ZEY3, RPOZ_CAMC1 ;  A7GXE4, RPOZ_CAMC5 ;  A8FMX9, RPOZ_CAMJ8 ;
DR   A7H2A7, RPOZ_CAMJD ;  Q9PN25, RPOZ_CAMJE ;  A1W0Q8, RPOZ_CAMJJ ;
DR   Q5HTJ0, RPOZ_CAMJR ;  B9KFW0, RPOZ_CAMLR ;  Q3AC15, RPOZ_CARHZ ;
DR   B8H618, RPOZ_CAUCN ;  P58066, RPOZ_CAUCR ;  B0T3H0, RPOZ_CAUSK ;
DR   Q1QSI0, RPOZ_CHRSD ;  Q7NRL2, RPOZ_CHRVO ;  A8ARN6, RPOZ_CITK8 ;
DR   A5CRX2, RPOZ_CLAM3 ;  B0REV6, RPOZ_CLAMS ;  Q97IC9, RPOZ_CLOAB ;
DR   A7FW79, RPOZ_CLOB1 ;  C3L0L4, RPOZ_CLOB6 ;  A6LSJ4, RPOZ_CLOB8 ;
DR   B2V4A8, RPOZ_CLOBA ;  B2THR8, RPOZ_CLOBB ;  A5I4U1, RPOZ_CLOBH ;
DR   C1FST3, RPOZ_CLOBJ ;  B1IIM4, RPOZ_CLOBK ;  A7GG99, RPOZ_CLOBL ;
DR   B1KX63, RPOZ_CLOBM ;  B8I2Z7, RPOZ_CLOCE ;  Q182S6, RPOZ_CLOD6 ;
DR   B9E1D8, RPOZ_CLOK1 ;  A5N7X7, RPOZ_CLOK5 ;  A0Q119, RPOZ_CLONN ;
DR   Q0TPK7, RPOZ_CLOP1 ;  Q8XJK9, RPOZ_CLOPE ;  A9KPG3, RPOZ_CLOPH ;
DR   Q0SS74, RPOZ_CLOPS ;  P60332, RPOZ_CLOTE ;  Q47UB2, RPOZ_COLP3 ;
DR   P60333, RPOZ_CORDI ;  Q8FT46, RPOZ_COREF ;  Q8NQ43, RPOZ_CORGL ;
DR   Q4JVH5, RPOZ_CORJK ;  B1VDN5, RPOZ_CORU7 ;  B6J5T7, RPOZ_COXB1 ;
DR   B6J202, RPOZ_COXB2 ;  A9KGR6, RPOZ_COXBN ;  A9NB36, RPOZ_COXBR ;
DR   Q83EL6, RPOZ_COXBU ;  Q0KD22, RPOZ_CUPNH ;  Q46YE9, RPOZ_CUPPJ ;
DR   B3R3N5, RPOZ_CUPTR ;  O19907, RPOZ_CYACA ;  Q85G45, RPOZ_CYAME ;
DR   B8HNJ0, RPOZ_CYAP4 ;  B7KF62, RPOZ_CYAP7 ;  Q479A9, RPOZ_DECAR ;
DR   C1CZ29, RPOZ_DEIDV ;  Q1J1S9, RPOZ_DEIGD ;  Q9RRJ6, RPOZ_DEIRA ;
DR   A9BTA2, RPOZ_DELAS ;  B8F9J5, RPOZ_DESAA ;  C6BYN6, RPOZ_DESAD ;
DR   C0QKM9, RPOZ_DESAH ;  B8J412, RPOZ_DESDA ;  Q316U8, RPOZ_DESDG ;
DR   B8FSC1, RPOZ_DESHD ;  Q24TX5, RPOZ_DESHY ;  C4XRE2, RPOZ_DESMR ;
DR   Q725M7, RPOZ_DESVH ;  B8DQW7, RPOZ_DESVM ;  A1V9Q4, RPOZ_DESVV ;
DR   A5EXW8, RPOZ_DICNV ;  B5YF48, RPOZ_DICT6 ;  B8E0X9, RPOZ_DICTD ;
DR   A8LLD2, RPOZ_DINSH ;  A7ZTK1, RPOZ_ECO24 ;  B7UM71, RPOZ_ECO27 ;
DR   B7MFL0, RPOZ_ECO45 ;  B7L773, RPOZ_ECO55 ;  P0A802, RPOZ_ECO57 ;
DR   B5YWE9, RPOZ_ECO5E ;  B7NQ13, RPOZ_ECO7I ;  B7N2X2, RPOZ_ECO81 ;
DR   B7M4D4, RPOZ_ECO8A ;  C4ZXP1, RPOZ_ECOBW ;  B1X982, RPOZ_ECODH ;
DR   A8A6B1, RPOZ_ECOHS ;  A1AHI0, RPOZ_ECOK1 ;  Q0TBG0, RPOZ_ECOL5 ;
DR   P0A801, RPOZ_ECOL6 ;  B1IYV1, RPOZ_ECOLC ;  P0A800, RPOZ_ECOLI ;
DR   B7NEV3, RPOZ_ECOLU ;  B6I3M8, RPOZ_ECOSE ;  B1LK86, RPOZ_ECOSM ;
DR   Q1R4U2, RPOZ_ECOUT ;  C5B9B3, RPOZ_EDWI9 ;  Q3YSH8, RPOZ_EHRCJ ;
DR   Q2GG39, RPOZ_EHRCR ;  Q5FHG7, RPOZ_EHRRG ;  Q5HBN0, RPOZ_EHRRW ;
DR   A4W500, RPOZ_ENT38 ;  Q82ZD6, RPOZ_ENTFA ;  A7MQB3, RPOZ_ENTS8 ;
DR   Q6DB61, RPOZ_ERWCT ;  B2VL59, RPOZ_ERWT9 ;  Q2N7Q3, RPOZ_ERYLH ;
DR   B7LVL1, RPOZ_ESCF3 ;  C4Z9X7, RPOZ_EUBR3 ;  B1YIQ5, RPOZ_EXIS2 ;
DR   C4L5X2, RPOZ_EXISA ;  B0S136, RPOZ_FINM2 ;  Q0RF85, RPOZ_FRAAA ;
DR   B0TZ05, RPOZ_FRAP2 ;  Q2J841, RPOZ_FRASC ;  A8LE17, RPOZ_FRASN ;
DR   Q14IC5, RPOZ_FRAT1 ;  A7NDN9, RPOZ_FRATF ;  Q2A273, RPOZ_FRATH ;
DR   B2SDK3, RPOZ_FRATM ;  A0Q5J3, RPOZ_FRATN ;  Q0BKU5, RPOZ_FRATO ;
DR   Q5NGX3, RPOZ_FRATT ;  A4IZA2, RPOZ_FRATW ;  B5E9N7, RPOZ_GEOBB ;
DR   Q5L0S7, RPOZ_GEOKA ;  B3E4R5, RPOZ_GEOLS ;  Q39T73, RPOZ_GEOMG ;
DR   B9M902, RPOZ_GEOSF ;  Q74AW2, RPOZ_GEOSL ;  C6E2G6, RPOZ_GEOSM ;
DR   C5D8R2, RPOZ_GEOSW ;  A5G6A4, RPOZ_GEOUR ;  Q7NK60, RPOZ_GLOVI ;
DR   A9HKY5, RPOZ_GLUDA ;  Q6B8L8, RPOZ_GRATL ;  O78442, RPOZ_GUITH ;
DR   Q7VKI2, RPOZ_HAEDU ;  Q4QJK4, RPOZ_HAEI8 ;  A5UBD9, RPOZ_HAEIE ;
DR   A5UFH3, RPOZ_HAEIG ;  P43740, RPOZ_HAEIN ;  B8F5Q2, RPOZ_HAEPS ;
DR   Q0I5L9, RPOZ_HAES1 ;  B0URZ0, RPOZ_HAES2 ;  Q2S8R3, RPOZ_HAHCH ;
DR   A1WVN4, RPOZ_HALHL ;  C4K473, RPOZ_HAMD5 ;  Q17Y32, RPOZ_HELAH ;
DR   Q7VHY0, RPOZ_HELHP ;  B0TGS4, RPOZ_HELMI ;  B6JM09, RPOZ_HELP2 ;
DR   Q1CT94, RPOZ_HELPH ;  P60326, RPOZ_HELPJ ;  B2UT54, RPOZ_HELPS ;
DR   P60325, RPOZ_HELPY ;  A4G6Y1, RPOZ_HERAR ;  Q0C3U4, RPOZ_HYPNA ;
DR   Q5QYI0, RPOZ_IDILO ;  A6SXM0, RPOZ_JANMA ;  Q28V32, RPOZ_JANSC ;
DR   A6WCB6, RPOZ_KINRD ;  B5XTE8, RPOZ_KLEP3 ;  A6TFP8, RPOZ_KLEP7 ;
DR   C5CGE8, RPOZ_KOSOT ;  Q5FJH3, RPOZ_LACAC ;  Q03RS0, RPOZ_LACBA ;
DR   Q038H0, RPOZ_LACC3 ;  B3WEX2, RPOZ_LACCB ;  Q1G9H9, RPOZ_LACDA ;
DR   Q049N8, RPOZ_LACDB ;  B2GD58, RPOZ_LACF3 ;  Q044H2, RPOZ_LACGA ;
DR   A8YVW4, RPOZ_LACH4 ;  Q74IM7, RPOZ_LACJO ;  Q9CEE4, RPOZ_LACLA ;
DR   A2RN34, RPOZ_LACLM ;  Q02WP2, RPOZ_LACLS ;  Q88WL6, RPOZ_LACPL ;
DR   A5VKQ8, RPOZ_LACRD ;  B2G842, RPOZ_LACRJ ;  Q1WUB4, RPOZ_LACS1 ;
DR   Q38XT9, RPOZ_LACSS ;  C1DC35, RPOZ_LARHH ;  Q5X3P3, RPOZ_LEGPA ;
DR   A5IDJ2, RPOZ_LEGPC ;  Q5WV31, RPOZ_LEGPL ;  Q6AF81, RPOZ_LEIXX ;
DR   B1Y0M2, RPOZ_LEPCP ;  Q92AI2, RPOZ_LISIN ;  C1KWC5, RPOZ_LISMC ;
DR   Q71YJ0, RPOZ_LISMF ;  B8DDS6, RPOZ_LISMH ;  Q8Y673, RPOZ_LISMO ;
DR   A0AJT1, RPOZ_LISW6 ;  B1HQE0, RPOZ_LYSSC ;  Q2W519, RPOZ_MAGSA ;
DR   A0L486, RPOZ_MAGSM ;  Q65RR6, RPOZ_MANSM ;  A1TYB4, RPOZ_MARAV ;
DR   Q0APB9, RPOZ_MARMM ;  A6W3K1, RPOZ_MARMS ;  Q11JT3, RPOZ_MESSB ;
DR   Q9MUL7, RPOZ_MESVI ;  B7KVD3, RPOZ_METC4 ;  Q606J4, RPOZ_METCA ;
DR   A9VYZ2, RPOZ_METEP ;  Q1GXB8, RPOZ_METFK ;  B8IT21, RPOZ_METNO ;
DR   B1ZJQ8, RPOZ_METPB ;  A2SJD1, RPOZ_METPP ;  B1LTE4, RPOZ_METRJ ;
DR   B0UN75, RPOZ_METS4 ;  B8EK21, RPOZ_METSB ;  B0JNU3, RPOZ_MICAN ;
DR   Q2RK30, RPOZ_MOOTA ;  A0QI28, RPOZ_MYCA1 ;  P66722, RPOZ_MYCBO ;
DR   A1KIH9, RPOZ_MYCBP ;  C1AN35, RPOZ_MYCBT ;  B8ZUM0, RPOZ_MYCLB ;
DR   Q9CCQ6, RPOZ_MYCLE ;  Q741G7, RPOZ_MYCPA ;  A0QWT1, RPOZ_MYCS2 ;
DR   A5U292, RPOZ_MYCTA ;  P66721, RPOZ_MYCTU ;  A1T8H5, RPOZ_MYCVP ;
DR   Q1D2S6, RPOZ_MYXXD ;  B9L8H3, RPOZ_NAUPA ;  Q5F776, RPOZ_NEIG1 ;
DR   B4RN20, RPOZ_NEIG2 ;  A9M1N1, RPOZ_NEIM0 ;  P66723, RPOZ_NEIMA ;
DR   P66724, RPOZ_NEIMB ;  A1KV69, RPOZ_NEIMF ;  Q2GF15, RPOZ_NEOSM ;
DR   Q0AD35, RPOZ_NITEC ;  Q82SQ2, RPOZ_NITEU ;  Q1QL49, RPOZ_NITHX ;
DR   Q2YD11, RPOZ_NITMU ;  Q3JBT2, RPOZ_NITOC ;  A6Q312, RPOZ_NITSB ;
DR   Q3SRA8, RPOZ_NITWN ;  Q5YTM8, RPOZ_NOCFA ;  A1SJF7, RPOZ_NOCSJ ;
DR   B2IUW7, RPOZ_NOSP7 ;  Q8YNB9, RPOZ_NOSS1 ;  Q2GC33, RPOZ_NOVAD ;
DR   Q8ER27, RPOZ_OCEIH ;  A6X296, RPOZ_OCHA4 ;  Q04EL5, RPOZ_OENOB ;
DR   B6JGF6, RPOZ_OLICO ;  A1B1V8, RPOZ_PARDP ;  A7HX41, RPOZ_PARL1 ;
DR   Q9CMB2, RPOZ_PASMU ;  C6DJC5, RPOZ_PECCP ;  Q03FY6, RPOZ_PEDPA ;
DR   Q3A522, RPOZ_PELCD ;  A1ARN6, RPOZ_PELPD ;  A5D1C3, RPOZ_PELTS ;
DR   Q4FLD7, RPOZ_PELUB ;  C0QR95, RPOZ_PERMH ;  A9BEX2, RPOZ_PETMO ;
DR   Q7N9P3, RPOZ_PHOLL ;  Q6LVP6, RPOZ_PHOPR ;  A1VKF1, RPOZ_POLNA ;
DR   B1XUH5, RPOZ_POLNS ;  Q12DV8, RPOZ_POLSJ ;  A4SXS9, RPOZ_POLSQ ;
DR   P51376, RPOZ_PORPU ;  Q1XDB1, RPOZ_PORYE ;  Q6A8H5, RPOZ_PROAC ;
DR   A3PER9, RPOZ_PROM0 ;  A2C4H7, RPOZ_PROM1 ;  A9BCB8, RPOZ_PROM4 ;
DR   A2BYF5, RPOZ_PROM5 ;  Q318W1, RPOZ_PROM9 ;  Q7VA81, RPOZ_PROMA ;
DR   B4EZA3, RPOZ_PROMH ;  Q7V5U8, RPOZ_PROMM ;  Q7V054, RPOZ_PROMP ;
DR   A2BT05, RPOZ_PROMS ;  Q46J74, RPOZ_PROMT ;  Q48Q16, RPOZ_PSE14 ;
DR   Q15Z09, RPOZ_PSEA6 ;  A6VEE4, RPOZ_PSEA7 ;  B7V5M8, RPOZ_PSEA8 ;
DR   Q02E25, RPOZ_PSEAB ;  Q9HTM1, RPOZ_PSEAE ;  Q1I2S9, RPOZ_PSEE4 ;
DR   Q4K3R3, RPOZ_PSEF5 ;  C3K482, RPOZ_PSEFS ;  Q3IJH7, RPOZ_PSEHT ;
DR   A4Y0M0, RPOZ_PSEMY ;  A5WB18, RPOZ_PSEP1 ;  Q3K4L7, RPOZ_PSEPF ;
DR   B0KQA1, RPOZ_PSEPG ;  Q88C82, RPOZ_PSEPK ;  B1J4N3, RPOZ_PSEPW ;
DR   Q88BE3, RPOZ_PSESM ;  Q4ZZY9, RPOZ_PSEU2 ;  A4VGR5, RPOZ_PSEU5 ;
DR   Q4FQY6, RPOZ_PSYA2 ;  Q1Q972, RPOZ_PSYCK ;  A1T0P2, RPOZ_PSYIN ;
DR   A5WCZ0, RPOZ_PSYWF ;  Q1LQ33, RPOZ_RALME ;  B2U8D3, RPOZ_RALPJ ;
DR   Q8XXG0, RPOZ_RALSO ;  B3PUN2, RPOZ_RHIE6 ;  Q2KAE9, RPOZ_RHIEC ;
DR   Q1MJ60, RPOZ_RHIL3 ;  Q985B3, RPOZ_RHILO ;  B5ZW67, RPOZ_RHILW ;
DR   Q92R52, RPOZ_RHIME ;  Q7UP93, RPOZ_RHOBA ;  B6IN07, RPOZ_RHOCS ;
DR   C0ZZD2, RPOZ_RHOE4 ;  Q21TP6, RPOZ_RHOFD ;  C1B4J5, RPOZ_RHOOB ;
DR   Q2IWV0, RPOZ_RHOP2 ;  Q07M70, RPOZ_RHOP5 ;  Q6N6C5, RPOZ_RHOPA ;
DR   Q214K2, RPOZ_RHOPB ;  Q136W4, RPOZ_RHOPS ;  B3QJG9, RPOZ_RHOPT ;
DR   Q2RT88, RPOZ_RHORT ;  A3PGF2, RPOZ_RHOS1 ;  Q3J5W7, RPOZ_RHOS4 ;
DR   A4WVQ1, RPOZ_RHOS5 ;  B9KSA1, RPOZ_RHOSK ;  Q0S0L6, RPOZ_RHOSR ;
DR   C3PP13, RPOZ_RICAE ;  A8GP45, RPOZ_RICAH ;  A8GW64, RPOZ_RICB8 ;
DR   Q1RHU0, RPOZ_RICBR ;  A8EYA7, RPOZ_RICCK ;  Q92H89, RPOZ_RICCN ;
DR   Q4UKX8, RPOZ_RICFE ;  Q9ZCX4, RPOZ_RICPR ;  C4K1J3, RPOZ_RICPU ;
DR   B0BYC5, RPOZ_RICRO ;  A8GSU9, RPOZ_RICRS ;  Q68WF8, RPOZ_RICTY ;
DR   Q16AJ3, RPOZ_ROSDO ;  Q1AVZ4, RPOZ_RUBXD ;  A1AW62, RPOZ_RUTMC ;
DR   Q21EC8, RPOZ_SACD2 ;  A4FBI2, RPOZ_SACEN ;  B5EY10, RPOZ_SALA4 ;
DR   A8LY23, RPOZ_SALAI ;  A9MKM3, RPOZ_SALAR ;  Q57I91, RPOZ_SALCH ;
DR   B5FM73, RPOZ_SALDC ;  B5QTY1, RPOZ_SALEP ;  B5RG73, RPOZ_SALG2 ;
DR   B4T9Z3, RPOZ_SALHS ;  B4SXF1, RPOZ_SALNS ;  Q5PC39, RPOZ_SALPA ;
DR   A9MVP7, RPOZ_SALPB ;  C0Q1Y1, RPOZ_SALPC ;  B5BI24, RPOZ_SALPK ;
DR   B4U000, RPOZ_SALSV ;  P0A804, RPOZ_SALTI ;  A4X624, RPOZ_SALTO ;
DR   P0A803, RPOZ_SALTY ;  A8GLH0, RPOZ_SERP5 ;  A1S270, RPOZ_SHEAM ;
DR   B8E4F6, RPOZ_SHEB2 ;  A3CZH4, RPOZ_SHEB5 ;  A6WI83, RPOZ_SHEB8 ;
DR   A9KXX5, RPOZ_SHEB9 ;  Q12IL7, RPOZ_SHEDO ;  Q088T8, RPOZ_SHEFN ;
DR   B0TPU5, RPOZ_SHEHH ;  A3QIR6, RPOZ_SHELP ;  Q8EJU7, RPOZ_SHEON ;
DR   A8H9F1, RPOZ_SHEPA ;  A4YBK6, RPOZ_SHEPC ;  B8CHM9, RPOZ_SHEPW ;
DR   A0L1W0, RPOZ_SHESA ;  A8FQ25, RPOZ_SHESH ;  Q0HE39, RPOZ_SHESM ;
DR   Q0HZX2, RPOZ_SHESR ;  A1RPI1, RPOZ_SHESW ;  Q7WZE4, RPOZ_SHEVD ;
DR   B1KLV2, RPOZ_SHEWM ;  B2TTX9, RPOZ_SHIB3 ;  Q31UQ7, RPOZ_SHIBS ;
DR   Q329K7, RPOZ_SHIDS ;  Q0SYH7, RPOZ_SHIF8 ;  Q83PM8, RPOZ_SHIFL ;
DR   Q3YW12, RPOZ_SHISS ;  Q5LNK0, RPOZ_SILPO ;  Q1GDG8, RPOZ_SILST ;
DR   A6U7A2, RPOZ_SINMW ;  Q2NQS8, RPOZ_SODGM ;  Q1GSQ7, RPOZ_SPHAL ;
DR   A5VC58, RPOZ_SPHWW ;  A7X1G4, RPOZ_STAA1 ;  A6U129, RPOZ_STAA2 ;
DR   Q2FHM8, RPOZ_STAA3 ;  Q2G1T9, RPOZ_STAA8 ;  A5IS95, RPOZ_STAA9 ;
DR   Q2YXF8, RPOZ_STAAB ;  Q5HGM2, RPOZ_STAAC ;  P66725, RPOZ_STAAM ;
DR   P66726, RPOZ_STAAN ;  Q6GHM5, RPOZ_STAAR ;  Q6GA03, RPOZ_STAAS ;
DR   A8Z3P7, RPOZ_STAAT ;  P66727, RPOZ_STAAW ;  B9DPL6, RPOZ_STACT ;
DR   Q5HPY0, RPOZ_STAEQ ;  Q8CSW3, RPOZ_STAES ;  Q4L5R2, RPOZ_STAHJ ;
DR   Q49WZ2, RPOZ_STAS1 ;  Q3K367, RPOZ_STRA1 ;  P66728, RPOZ_STRA3 ;
DR   P66729, RPOZ_STRA5 ;  Q827Q2, RPOZ_STRAW ;  Q9KXS1, RPOZ_STRCO ;
DR   C0M782, RPOZ_STRE4 ;  B4U4H7, RPOZ_STREM ;  B1W468, RPOZ_STRGG ;
DR   Q8GAU3, RPOZ_STRKA ;  B4STZ5, RPOZ_STRM5 ;  B2FT05, RPOZ_STRMK ;
DR   Q8DVK5, RPOZ_STRMU ;  P68840, RPOZ_STRP1 ;  Q04J38, RPOZ_STRP2 ;
DR   P0DF36, RPOZ_STRP3 ;  B5E7F9, RPOZ_STRP4 ;  Q5XAP2, RPOZ_STRP6 ;
DR   C1C8X4, RPOZ_STRP7 ;  P68842, RPOZ_STRP8 ;  Q1JAJ5, RPOZ_STRPB ;
DR   Q1JKP7, RPOZ_STRPC ;  Q1JFN8, RPOZ_STRPD ;  Q1J5I7, RPOZ_STRPF ;
DR   A2RD68, RPOZ_STRPG ;  B1I7K0, RPOZ_STRPI ;  B8ZMR0, RPOZ_STRPJ ;
DR   Q48S19, RPOZ_STRPM ;  P66730, RPOZ_STRPN ;  P0DF37, RPOZ_STRPQ ;
DR   B2IS88, RPOZ_STRPS ;  B5XMI5, RPOZ_STRPZ ;  P66731, RPOZ_STRR6 ;
DR   A4VZM9, RPOZ_STRS2 ;  C0MH28, RPOZ_STRS7 ;  A3CPX6, RPOZ_STRSV ;
DR   A4VTF1, RPOZ_STRSY ;  Q5LYX2, RPOZ_STRT1 ;  Q5M3I5, RPOZ_STRT2 ;
DR   Q03JR1, RPOZ_STRTD ;  B9DV47, RPOZ_STRU0 ;  C1CFV9, RPOZ_STRZJ ;
DR   C1CM73, RPOZ_STRZP ;  C1CSZ6, RPOZ_STRZT ;  A6QB34, RPOZ_SULNB ;
DR   Q67PR8, RPOZ_SYMTH ;  Q2LQ83, RPOZ_SYNAS ;  Q31MH9, RPOZ_SYNE7 ;
DR   A0LJ43, RPOZ_SYNFM ;  Q2JXT8, RPOZ_SYNJA ;  Q2JJC6, RPOZ_SYNJB ;
DR   B1XPZ2, RPOZ_SYNP2 ;  Q5MZE9, RPOZ_SYNP6 ;  A5GNA0, RPOZ_SYNPW ;
DR   Q7U8T6, RPOZ_SYNPX ;  Q0I7V6, RPOZ_SYNS3 ;  Q3AZJ0, RPOZ_SYNS9 ;
DR   Q3AHN5, RPOZ_SYNSC ;  Q0AXK9, RPOZ_SYNWW ;  P74352, RPOZ_SYNY3 ;
DR   C5BLF6, RPOZ_TERTT ;  B7IFG6, RPOZ_THEAB ;  Q9EVV4, RPOZ_THEAQ ;
DR   Q8DGQ8, RPOZ_THEEB ;  Q47R16, RPOZ_THEFY ;  A6LJ74, RPOZ_THEM4 ;
DR   Q9X214, RPOZ_THEMA ;  B9K7W8, RPOZ_THENN ;  A5ILC9, RPOZ_THEP1 ;
DR   B0KA14, RPOZ_THEP3 ;  B0K295, RPOZ_THEPX ;  B1LAZ3, RPOZ_THESQ ;
DR   Q72ID6, RPOZ_THET2 ;  Q8RQE7, RPOZ_THET8 ;  Q8R9S7, RPOZ_THETN ;
DR   B5YJ35, RPOZ_THEYD ;  Q31DP2, RPOZ_THICR ;  Q3SLI5, RPOZ_THIDA ;
DR   B8GQN1, RPOZ_THISH ;  C4L810, RPOZ_TOLAT ;  O83699, RPOZ_TREPA ;
DR   Q10YY8, RPOZ_TRIEI ;  Q820D7, RPOZ_TROW8 ;  Q820D5, RPOZ_TROWT ;
DR   C5CYY0, RPOZ_VARPS ;  A1WQL7, RPOZ_VEREI ;  A5CX12, RPOZ_VESOH ;
DR   A5F4S8, RPOZ_VIBC3 ;  Q9KNM3, RPOZ_VIBCH ;  C3LSD6, RPOZ_VIBCM ;
DR   Q5E8P6, RPOZ_VIBF1 ;  B5FFD6, RPOZ_VIBFM ;  Q87TB0, RPOZ_VIBPA ;
DR   B7VHI0, RPOZ_VIBSL ;  Q8DDV5, RPOZ_VIBVU ;  Q7MPX0, RPOZ_VIBVY ;
DR   Q8D2E9, RPOZ_WIGBR ;  Q73FM5, RPOZ_WOLPM ;  B3CMP5, RPOZ_WOLPP ;
DR   Q7MSQ0, RPOZ_WOLSU ;  Q5GSP9, RPOZ_WOLTR ;  C0R512, RPOZ_WOLWR ;
DR   P66732, RPOZ_XANAC ;  Q3BPS1, RPOZ_XANC5 ;  Q4UY42, RPOZ_XANC8 ;
DR   B0RP99, RPOZ_XANCB ;  P66733, RPOZ_XANCP ;  Q2P6M7, RPOZ_XANOM ;
DR   Q5H3R9, RPOZ_XANOR ;  A7IM18, RPOZ_XANP2 ;  Q9PD77, RPOZ_XYLFA ;
DR   B0U6W4, RPOZ_XYLFM ;  Q87DG6, RPOZ_XYLFT ;  A1JHV7, RPOZ_YERE8 ;
DR   A7FCR3, RPOZ_YERP3 ;  Q1C257, RPOZ_YERPA ;  B2JYM2, RPOZ_YERPB ;
DR   Q8ZJQ3, RPOZ_YERPE ;  A9R664, RPOZ_YERPG ;  Q1CCZ2, RPOZ_YERPN ;
DR   A4TSE7, RPOZ_YERPP ;  Q66GE6, RPOZ_YERPS ;  B1JQZ5, RPOZ_YERPY ;
DR   Q5NLR6, RPOZ_ZYMMO ;  Q5UQW1, YL376_MIMIV;  Q5UQD9, YR470_MIMIV;
//
ID   2.7.7.7
DE   DNA-directed DNA polymerase.
AN   DNA nucleotidyltransferase (DNA-directed).
AN   DNA-dependent DNA polymerase.
CA   Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
CC   -!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA
CC       strand by one nucleotide at a time.
CC   -!- Cannot initiate a chain de novo.
CC   -!- Requires a primer which may be DNA or RNA.
CC   -!- See also EC 2.7.7.49.
PR   PROSITE; PDOC00107;
PR   PROSITE; PDOC00412;
PR   PROSITE; PDOC00452;
DR   B9JWL2, DNAE2_AGRVS;  Q0A9G3, DNAE2_ALHEH;  B8JAF5, DNAE2_ANAD2;
DR   Q2IIA8, DNAE2_ANADE;  B4UDQ9, DNAE2_ANASK;  Q5P4A4, DNAE2_AROAE;
DR   A1KCL7, DNAE2_AZOSB;  Q6MQS6, DNAE2_BDEBA;  Q7WHW8, DNAE2_BORBR;
DR   Q7W9W1, DNAE2_BORPA;  Q89QU8, DNAE2_BRAJA;  A4YRD9, DNAE2_BRASO;
DR   Q57FU7, DNAE2_BRUAB;  Q8YEK2, DNAE2_BRUME;  Q8G381, DNAE2_BRUSU;
DR   Q62F99, DNAE2_BURMA;  Q63XR8, DNAE2_BURPS;  B8H427, DNAE2_CAUCN;
DR   Q9A3J3, DNAE2_CAUCR;  Q6NJ04, DNAE2_CORDI;  Q8FRX6, DNAE2_COREF;
DR   Q6M7C6, DNAE2_CORGL;  Q4JTH1, DNAE2_CORJK;  Q47EP3, DNAE2_DECAR;
DR   Q5HXU1, DNAE2_GLUOX;  Q2SJZ6, DNAE2_HAHCH;  Q5QUT9, DNAE2_IDILO;
DR   Q605W1, DNAE2_METCA;  Q7TWL9, DNAE2_MYCBO;  Q73U92, DNAE2_MYCPA;
DR   O50399, DNAE2_MYCTU;  Q5Z1D1, DNAE2_NOCFA;  Q6A780, DNAE2_PROAC;
DR   Q48IB1, DNAE2_PSE14;  A6VAU7, DNAE2_PSEA7;  Q9I5Q2, DNAE2_PSEAE;
DR   Q4KAD4, DNAE2_PSEF5;  A4XTN0, DNAE2_PSEMY;  Q3KBG7, DNAE2_PSEPF;
DR   Q88I82, DNAE2_PSEPK;  Q881T7, DNAE2_PSESM;  Q4ZTG0, DNAE2_PSEU2;
DR   B2UJ29, DNAE2_RALPJ;  Q8XRN1, DNAE2_RALSO;  Q98E34, DNAE2_RHILO;
DR   C3M9Z5, DNAE2_RHISN;  Q7UXK9, DNAE2_RHOBA;  Q2IU52, DNAE2_RHOP2;
DR   Q07QK9, DNAE2_RHOP5;  Q6N8V0, DNAE2_RHOPA;  Q139V1, DNAE2_RHOPS;
DR   Q21LY9, DNAE2_SACD2;  Q5LVN0, DNAE2_SILPO;  A6UDW8, DNAE2_SINMW;
DR   Q67N73, DNAE2_SYMTH;  C5BNE0, DNAE2_TERTT;  A7MUN4, DNAE2_VIBHB;
DR   Q87N39, DNAE2_VIBPA;  Q8D8I6, DNAE2_VIBVU;  Q7MLY4, DNAE2_VIBVY;
DR   Q8PN74, DNAE2_XANAC;  Q3BWA6, DNAE2_XANC5;  Q4URY1, DNAE2_XANC8;
DR   B0RY89, DNAE2_XANCB;  Q8PBL8, DNAE2_XANCP;  B2SI43, DNAE2_XANOP;
DR   Q5GX78, DNAE2_XANOR;  Q8UAY9, DNE21_AGRT5;  Q92LA6, DNE21_RHIME;
DR   Q8UKK2, DNE22_AGRT5;  Q92ZJ6, DNE22_RHIME;  Q8U642, DNE23_AGRT5;
DR   O28552, DP2L_ARCFU ;  A0RYM0, DP2L_CENSY ;  Q5UZ40, DP2L_HALMA ;
DR   Q9HMX8, DP2L_HALSA ;  Q18ER3, DP2L_HALWD ;  Q8THG5, DP2L_METAC ;
DR   Q46E19, DP2L_METBF ;  Q12TF2, DP2L_METBU ;  Q2FSF9, DP2L_METHJ ;
DR   Q59024, DP2L_METJA ;  Q8TUV3, DP2L_METKA ;  A2SU54, DP2L_METLZ ;
DR   A4G0G9, DP2L_METM5 ;  A9A8R5, DP2L_METM6 ;  A6VI14, DP2L_METM7 ;
DR   Q8PXH2, DP2L_METMA ;  A3CXE7, DP2L_METMJ ;  Q6M191, DP2L_METMP ;
DR   Q2NHG2, DP2L_METST ;  O27579, DP2L_METTH ;  A0B8K5, DP2L_METTP ;
DR   A6URH2, DP2L_METVS ;  Q74N29, DP2L_NANEQ ;  Q3IU54, DP2L_NATPD ;
DR   Q6L1K9, DP2L_PICTO ;  Q9V2F4, DP2L_PYRAB ;  P81409, DP2L_PYRFU ;
DR   O57861, DP2L_PYRHO ;  Q5JET0, DP2L_PYRKO ;  Q9HM33, DP2L_THEAC ;
DR   Q97CR6, DP2L_THEVO ;  Q0W5U6, DP2L_UNCMA ;  O28484, DP2S_ARCFU ;
DR   B0R7U1, DP2S_HALS3 ;  Q9HMR7, DP2S_HALSA ;  Q58113, DP2S_METJA ;
DR   O27456, DP2S_METTH ;  Q9V2F3, DP2S_PYRAB ;  P81412, DP2S_PYRFU ;
DR   O57863, DP2S_PYRHO ;  Q9HLK5, DP2S_THEAC ;  Q758V1, DPB2_ASHGO ;
DR   Q6FSK8, DPB2_CANGA ;  P0CN25, DPB2_CRYNB ;  P0CN24, DPB2_CRYNJ ;
DR   Q6BQR8, DPB2_DEBHA ;  Q6CPH8, DPB2_KLULA ;  O94263, DPB2_SCHPO ;
DR   Q6C030, DPB2_YARLI ;  P24482, DPB2_YEAST ;  Q6FXJ8, DPB3_CANGA ;
DR   Q6BX14, DPB3_DEBHA ;  Q6CLM5, DPB3_KLULA ;  Q10315, DPB3_SCHPO ;
DR   Q6C6M5, DPB3_YARLI ;  P27344, DPB3_YEAST ;  Q750A4, DPB4_ASHGO ;
DR   Q6FXD0, DPB4_CANGA ;  Q6BIP4, DPB4_DEBHA ;  Q6CJD7, DPB4_KLULA ;
DR   P87174, DPB4_SCHPO ;  Q6CHS6, DPB4_YARLI ;  Q04603, DPB4_YEAST ;
DR   P30313, DPO1F_THETH;  P52028, DPO1T_THET8;  Q59156, DPO1_ANATD ;
DR   O67779, DPO1_AQUAE ;  Q04957, DPO1_BACCA ;  O34996, DPO1_BACSU ;
DR   O51498, DPO1_BORBU ;  O08307, DPO1_CHLAA ;  P52027, DPO1_DEIRA ;
DR   P00582, DPO1_ECOLI ;  P52026, DPO1_GEOSE ;  P43741, DPO1_HAEIN ;
DR   Q9ZJE9, DPO1_HELPJ ;  P56105, DPO1_HELPY ;  P09804, DPO1_KLULA ;
DR   Q9CDS1, DPO1_LACLA ;  O32801, DPO1_LACLM ;  P0A551, DPO1_MYCBO ;
DR   P46835, DPO1_MYCLE ;  P0A550, DPO1_MYCTU ;  Q9HT80, DPO1_PSEAE ;
DR   Q9S1G2, DPO1_RHILE ;  Q1RH76, DPO1_RICBR ;  Q92GB7, DPO1_RICCN ;
DR   Q9RAA9, DPO1_RICFE ;  Q9RLB6, DPO1_RICHE ;  O05949, DPO1_RICPR ;
DR   Q9RLA0, DPO1_RICTY ;  Q9F173, DPO1_SALTY ;  P59199, DPO1_STRPN ;
DR   P59200, DPO1_STRR6 ;  Q55971, DPO1_SYNY3 ;  P19821, DPO1_THEAQ ;
DR   P80194, DPO1_THECA ;  O52225, DPO1_THEFI ;  P74933, DPO1_TREPA ;
DR   P21189, DPO2_ECOLI ;  P05468, DPO2_KLULA ;  O67125, DPO3A_AQUAE;
DR   Q9K838, DPO3A_BACHD;  O34623, DPO3A_BACSU;  O51526, DPO3A_BORBU;
DR   P57332, DPO3A_BUCAI;  Q8K9S3, DPO3A_BUCAP;  Q89AN8, DPO3A_BUCBP;
DR   Q9PPI9, DPO3A_CAMJE;  B8GWS6, DPO3A_CAUCN;  Q9A700, DPO3A_CAUCR;
DR   Q9PJJ7, DPO3A_CHLMU;  Q9Z7N8, DPO3A_CHLPN;  O84549, DPO3A_CHLTR;
DR   Q9RX08, DPO3A_DEIRA;  Q8X8X5, DPO3A_ECO57;  Q8FL05, DPO3A_ECOL6;
DR   P10443, DPO3A_ECOLI;  P43743, DPO3A_HAEIN;  Q9ZJF9, DPO3A_HELPJ;
DR   P56157, DPO3A_HELPY;  Q9CI70, DPO3A_LACLA;  P63978, DPO3A_MYCBO;
DR   Q49405, DPO3A_MYCGE;  Q9X7F0, DPO3A_MYCLE;  P75404, DPO3A_MYCPN;
DR   P63977, DPO3A_MYCTU;  Q9JVX8, DPO3A_NEIMA;  Q9JXZ2, DPO3A_NEIMB;
DR   Q9CPK3, DPO3A_PASMU;  Q9HXZ1, DPO3A_PSEAE;  Q9XDH6, DPO3A_PSEFL;
DR   Q1RKF9, DPO3A_RICBR;  Q92GB2, DPO3A_RICCN;  Q4UK40, DPO3A_RICFE;
DR   O05974, DPO3A_RICPR;  Q68VX1, DPO3A_RICTY;  P34699, DPO3A_SACEN;
DR   P14567, DPO3A_SALTY;  Q9F1K0, DPO3A_STAA8;  Q5HF71, DPO3A_STAAC;
DR   P63979, DPO3A_STAAM;  P63980, DPO3A_STAAN;  Q6GG04, DPO3A_STAAR;
DR   Q6G8M4, DPO3A_STAAS;  Q8NW58, DPO3A_STAAW;  Q5HNK2, DPO3A_STAEQ;
DR   Q8CNX0, DPO3A_STAES;  Q9Z618, DPO3A_STRCO;  P0C0F3, DPO3A_STRP1;
DR   P0DA74, DPO3A_STRP3;  Q5XBV1, DPO3A_STRP6;  Q8P0S5, DPO3A_STRP8;
DR   P0DA75, DPO3A_STRPQ;  P0C0F2, DPO3A_STRPY;  P74750, DPO3A_SYNY3;
DR   Q9XDH5, DPO3A_THEAQ;  Q9ZHG4, DPO3A_THEMA;  O83675, DPO3A_TREPA;
DR   Q9PQ74, DPO3A_UREPA;  P52022, DPO3A_VIBCH;  Q9PGU4, DPO3A_XYLFA;
DR   Q87EY0, DPO3A_XYLFT;  O68770, DPO3A_YERPE;  P24701, DPO3B_ACTPL;
DR   O67725, DPO3B_AQUAE;  Q9RCA1, DPO3B_BACHD;  P05649, DPO3B_BACSU;
DR   P33761, DPO3B_BORBU;  P57127, DPO3B_BUCAI;  P29439, DPO3B_BUCAP;
DR   Q89B36, DPO3B_BUCBP;  Q9EVE4, DPO3B_BUCRP;  B8GXP6, DPO3B_CAUCN;
DR   P0CAU5, DPO3B_CAUCR;  Q9PKW4, DPO3B_CHLMU;  Q9Z8K0, DPO3B_CHLPN;
DR   O84078, DPO3B_CHLTR;  P0A990, DPO3B_ECO57;  P0A989, DPO3B_ECOL6;
DR   P0A988, DPO3B_ECOLI;  P43744, DPO3B_HAEIN;  Q9ZLX4, DPO3B_HELPJ;
DR   O25242, DPO3B_HELPY;  Q9CJJ1, DPO3B_LACLA;  O54376, DPO3B_LACLM;
DR   P21174, DPO3B_MICLU;  O33914, DPO3B_MYCBO;  P24117, DPO3B_MYCCT;
DR   P47247, DPO3B_MYCGE;  P46387, DPO3B_MYCLE;  Q9L7L6, DPO3B_MYCPA;
DR   Q50313, DPO3B_MYCPN;  Q98RK6, DPO3B_MYCPU;  P52851, DPO3B_MYCSM;
DR   Q50790, DPO3B_MYCTU;  P22838, DPO3B_PROMI;  Q9I7C4, DPO3B_PSEAE;
DR   P0A120, DPO3B_PSEPK;  P0A121, DPO3B_PSEPU;  P31861, DPO3B_RHOCA;
DR   Q1RIS7, DPO3B_RICBR;  Q92I37, DPO3B_RICCN;  Q4ULS3, DPO3B_RICFE;
DR   Q9ZDB3, DPO3B_RICPR;  Q68WW0, DPO3B_RICTY;  P26464, DPO3B_SALTY;
DR   P29438, DPO3B_SERMA;  P34029, DPO3B_SPICI;  Q5HJZ4, DPO3B_STAAC;
DR   P0A022, DPO3B_STAAM;  P99103, DPO3B_STAAN;  Q6GKU3, DPO3B_STAAR;
DR   Q6GD88, DPO3B_STAAS;  P0A024, DPO3B_STAAU;  P0A023, DPO3B_STAAW;
DR   Q5HK00, DPO3B_STAEQ;  Q8CQK6, DPO3B_STAES;  P27903, DPO3B_STRCO;
DR   O06672, DPO3B_STRPN;  P59651, DPO3B_STRR6;  P52023, DPO3B_SYNE7;
DR   P72856, DPO3B_SYNY3;  O83048, DPO3B_TREPA;  Q9KVX5, DPO3B_VIBCH;
DR   P52620, DPO3B_VIBHA;  O67074, DPO3E_AQUAE;  P57337, DPO3E_BUCAI;
DR   Q08880, DPO3E_BUCAP;  Q89AN3, DPO3E_BUCBP;  P03007, DPO3E_ECOLI;
DR   P43745, DPO3E_HAEIN;  Q9CPE0, DPO3E_PASMU;  O68045, DPO3E_RHOCB;
DR   Q1RJM1, DPO3E_RICBR;  Q92GL1, DPO3E_RICCN;  Q4UN31, DPO3E_RICFE;
DR   Q9ZCJ9, DPO3E_RICPR;  Q68W16, DPO3E_RICTY;  P0A1H0, DPO3E_SALTI;
DR   P0A1G9, DPO3E_SALTY;  O83649, DPO3E_TREPA;  P09122, DPO3X_BACSU;
DR   P57553, DPO3X_BUCAI;  Q8K983, DPO3X_BUCAP;  Q89A95, DPO3X_BUCBP;
DR   P06710, DPO3X_ECOLI;  P43746, DPO3X_HAEIN;  P63976, DPO3X_MYCBO;
DR   P47658, DPO3X_MYCGE;  P75177, DPO3X_MYCPN;  P63975, DPO3X_MYCTU;
DR   P74876, DPO3X_SALTY;  Q819Y5, DPO3_BACCR ;  Q9KA72, DPO3_BACHD ;
DR   P13267, DPO3_BACSU ;  Q8XJR3, DPO3_CLOPE ;  Q895K2, DPO3_CLOTE ;
DR   Q03QS9, DPO3_LACBA ;  Q038M0, DPO3_LACC3 ;  Q9CDT7, DPO3_LACLA ;
DR   Q88VK2, DPO3_LACPL ;  A5VJD5, DPO3_LACRD ;  Q1WUF9, DPO3_LACS1 ;
DR   Q38W73, DPO3_LACSS ;  Q92C34, DPO3_LISIN ;  Q720A2, DPO3_LISMF ;
DR   Q8Y7G1, DPO3_LISMO ;  A0AIC1, DPO3_LISW6 ;  P47277, DPO3_MYCGE ;
DR   P75080, DPO3_MYCPN ;  P47729, DPO3_MYCPU ;  Q8EQU6, DPO3_OCEIH ;
DR   Q03FS8, DPO3_PEDPA ;  A7X1P4, DPO3_STAA1 ;  Q2FHH4, DPO3_STAA3 ;
DR   Q2G1Z8, DPO3_STAA8 ;  Q2YXK4, DPO3_STAAB ;  Q5HGG7, DPO3_STAAC ;
DR   A6QGG4, DPO3_STAAE ;  P63981, DPO3_STAAM ;  P63982, DPO3_STAAN ;
DR   Q6GHH1, DPO3_STAAR ;  Q6G9U9, DPO3_STAAS ;  P0C1P9, DPO3_STAAU ;
DR   P68852, DPO3_STAAW ;  Q5HPS7, DPO3_STAEQ ;  Q8CPG6, DPO3_STAES ;
DR   Q4L5W6, DPO3_STAHJ ;  Q49X49, DPO3_STAS1 ;  P63983, DPO3_STRA3 ;
DR   P63984, DPO3_STRA5 ;  Q8DWE0, DPO3_STRMU ;  P0C0B8, DPO3_STRP1 ;
DR   Q04MH6, DPO3_STRP2 ;  P0DA76, DPO3_STRP3 ;  Q5X9U8, DPO3_STRP6 ;
DR   Q8NZB5, DPO3_STRP8 ;  Q1J9R4, DPO3_STRPB ;  Q1JJW3, DPO3_STRPC ;
DR   Q1JEV4, DPO3_STRPD ;  Q1J4M0, DPO3_STRPF ;  A2RGI3, DPO3_STRPG ;
DR   Q48R90, DPO3_STRPM ;  Q97SQ2, DPO3_STRPN ;  P0DA77, DPO3_STRPQ ;
DR   P0C0B7, DPO3_STRPY ;  Q8DRA5, DPO3_STRR6 ;  A4W428, DPO3_STRS2 ;
DR   A3CQI2, DPO3_STRSV ;  A4VXT1, DPO3_STRSY ;  Q5M1Y0, DPO3_STRT1 ;
DR   Q5M6H0, DPO3_STRT2 ;  Q03MX3, DPO3_STRTD ;  Q9ZHF6, DPO3_THEMA ;
DR   A5IJJ8, DPO3_THEP1 ;  Q8RA32, DPO3_THETN ;  Q9PQB4, DPO3_UREPA ;
DR   Q8UFV3, DPO41_AGRT5;  Q9KCU7, DPO41_BACHD;  P54545, DPO41_BACSU;
DR   Q8PYH6, DPO41_METMA;  P63986, DPO41_MYCBO;  P63985, DPO41_MYCTU;
DR   Q98LV1, DPO41_RHILO;  Q92QM8, DPO41_RHIME;  Q8UJK7, DPO42_AGRT5;
DR   Q9K9A8, DPO42_BACHD;  P54560, DPO42_BACSU;  Q8PT42, DPO42_METMA;
DR   P63988, DPO42_MYCBO;  P63987, DPO42_MYCTU;  Q98JM5, DPO42_RHILO;
DR   Q92XH8, DPO42_RHIME;  Q98NW7, DPO43_RHILO;  Q6FFG4, DPO4_ACIAD ;
DR   A3N148, DPO4_ACTP2 ;  B0BPX9, DPO4_ACTPJ ;  A0KHD5, DPO4_AERHH ;
DR   B2UKN1, DPO4_AKKM8 ;  Q0A4X2, DPO4_ALHEH ;  A8MGJ5, DPO4_ALKOO ;
DR   A7Z6F3, DPO4_BACA2 ;  Q81M86, DPO4_BACAN ;  Q818U9, DPO4_BACCR ;
DR   Q635E0, DPO4_BACCZ ;  Q64X95, DPO4_BACFR ;  Q8YC76, DPO4_BRUME ;
DR   Q8FW50, DPO4_BRUSU ;  Q3ABL2, DPO4_CARHZ ;  Q9A5I1, DPO4_CAUCR ;
DR   A8AKQ2, DPO4_CITK8 ;  Q97MB3, DPO4_CLOAB ;  Q18A91, DPO4_CLOD6 ;
DR   A5N2U5, DPO4_CLOK5 ;  Q0TQ38, DPO4_CLOP1 ;  Q8XK37, DPO4_CLOPE ;
DR   Q0SSQ2, DPO4_CLOPS ;  A3DH61, DPO4_CLOTH ;  Q487H6, DPO4_COLP3 ;
DR   Q6NGD8, DPO4_CORDI ;  A4QFK8, DPO4_CORGB ;  Q8NNP4, DPO4_CORGL ;
DR   Q3ZAI3, DPO4_DEHE1 ;  A5FSS1, DPO4_DEHSB ;  Q3ZWB2, DPO4_DEHSC ;
DR   B8FBE8, DPO4_DESAA ;  Q6AL48, DPO4_DESPS ;  A7ZHZ2, DPO4_ECO24 ;
DR   Q8X7Q1, DPO4_ECO57 ;  A7ZWJ6, DPO4_ECOHS ;  A1A7U2, DPO4_ECOK1 ;
DR   Q0TL85, DPO4_ECOL5 ;  P59477, DPO4_ECOL6 ;  B1J100, DPO4_ECOLC ;
DR   Q47155, DPO4_ECOLI ;  Q1RFU0, DPO4_ECOUT ;  A4W6W8, DPO4_ENT38 ;
DR   A7MEN4, DPO4_ENTS8 ;  Q6D1H8, DPO4_ERWCT ;  P58963, DPO4_ESCFE ;
DR   B1YK83, DPO4_EXIS2 ;  B0TZS5, DPO4_FRAP2 ;  A7NC07, DPO4_FRATF ;
DR   Q2A3L2, DPO4_FRATH ;  B2SH34, DPO4_FRATM ;  A0Q6K9, DPO4_FRATN ;
DR   Q0BM23, DPO4_FRATO ;  Q8REB0, DPO4_FUSNN ;  Q5FSM8, DPO4_GLUOX ;
DR   B8F542, DPO4_HAEPS ;  A1WY69, DPO4_HALHL ;  B0R4P0, DPO4_HALS3 ;
DR   Q9HQT4, DPO4_HALSA ;  Q9CE21, DPO4_LACLA ;  A2RNH9, DPO4_LACLM ;
DR   Q02WA3, DPO4_LACLS ;  Q88V07, DPO4_LACPL ;  Q5X7J1, DPO4_LEGPA ;
DR   A5IH02, DPO4_LEGPC ;  Q5ZY20, DPO4_LEGPH ;  Q5WYY8, DPO4_LEGPL ;
DR   Q72MY7, DPO4_LEPIC ;  Q8F8Q2, DPO4_LEPIN ;  Q92A40, DPO4_LISIN ;
DR   C1KWR9, DPO4_LISMC ;  Q71Y46, DPO4_LISMF ;  B8DBV7, DPO4_LISMH ;
DR   Q8Y5T0, DPO4_LISMO ;  A0AK80, DPO4_LISW6 ;  Q65TG8, DPO4_MANSM ;
DR   A1U339, DPO4_MARAV ;  A6W1V6, DPO4_MARMS ;  Q8TIW3, DPO4_METAC ;
DR   A3CSG3, DPO4_METMJ ;  A4YEC1, DPO4_METS5 ;  Q2RJ46, DPO4_MOOTA ;
DR   Q5F8N2, DPO4_NEIG1 ;  Q9JRG1, DPO4_NEIMA ;  Q9JYS8, DPO4_NEIMB ;
DR   A1KUQ3, DPO4_NEIMF ;  A9A3A9, DPO4_NITMS ;  Q8EQ56, DPO4_OCEIH ;
DR   B1ZN03, DPO4_OPITP ;  Q6MA55, DPO4_PARUW ;  Q9CNG4, DPO4_PASMU ;
DR   A5D243, DPO4_PELTS ;  Q7N7B6, DPO4_PHOLL ;  Q6KZW2, DPO4_PICTO ;
DR   Q6A763, DPO4_PROAC ;  Q48FB2, DPO4_PSE14 ;  Q15YP8, DPO4_PSEA6 ;
DR   A6VA50, DPO4_PSEA7 ;  Q02I83, DPO4_PSEAB ;  Q9I534, DPO4_PSEAE ;
DR   Q1I6D5, DPO4_PSEE4 ;  Q3II35, DPO4_PSEHT ;  A4XT24, DPO4_PSEMY ;
DR   A5VZT3, DPO4_PSEP1 ;  Q3KH18, DPO4_PSEPF ;  B0KTK6, DPO4_PSEPG ;
DR   Q88NK4, DPO4_PSEPK ;  Q87Y22, DPO4_PSESM ;  Q4ZWM4, DPO4_PSEU2 ;
DR   Q8XZ19, DPO4_RALSO ;  Q7USY7, DPO4_RHOBA ;  A9MNS1, DPO4_SALAR ;
DR   Q57SU1, DPO4_SALCH ;  Q5PF76, DPO4_SALPA ;  A9MY13, DPO4_SALPB ;
DR   P63990, DPO4_SALTI ;  P63989, DPO4_SALTY ;  A8GAC8, DPO4_SERP5 ;
DR   A1S8M3, DPO4_SHEAM ;  A3D147, DPO4_SHEB5 ;  A6WRW5, DPO4_SHEB8 ;
DR   A9L0T3, DPO4_SHEB9 ;  Q12Q05, DPO4_SHEDO ;  Q086K1, DPO4_SHEFN ;
DR   B0TQD1, DPO4_SHEHH ;  A3QGY9, DPO4_SHELP ;  Q8EHU9, DPO4_SHEON ;
DR   A8H771, DPO4_SHEPA ;  A0KTR5, DPO4_SHESA ;  A8FYV3, DPO4_SHESH ;
DR   Q0HLP0, DPO4_SHESM ;  Q0HY21, DPO4_SHESR ;  A1RMZ5, DPO4_SHESW ;
DR   B1KD33, DPO4_SHEWM ;  B2U3S3, DPO4_SHIB3 ;  Q32J17, DPO4_SHIDS ;
DR   Q83M86, DPO4_SHIFL ;  Q3Z5A4, DPO4_SHISS ;  A7X420, DPO4_STAA1 ;
DR   A6U2Z9, DPO4_STAA2 ;  A5IU61, DPO4_STAA9 ;  Q2YU32, DPO4_STAAB ;
DR   Q5HEM7, DPO4_STAAC ;  A6QIC3, DPO4_STAAE ;  P63991, DPO4_STAAM ;
DR   P63992, DPO4_STAAN ;  Q6GFG2, DPO4_STAAR ;  Q6G838, DPO4_STAAS ;
DR   P58964, DPO4_STAAW ;  B9DMT3, DPO4_STACT ;  Q5HN39, DPO4_STAEQ ;
DR   Q8CNP3, DPO4_STAES ;  Q4L7K8, DPO4_STAHJ ;  Q49YT9, DPO4_STAS1 ;
DR   Q3JZG9, DPO4_STRA1 ;  Q8E3I8, DPO4_STRA3 ;  Q8DXW9, DPO4_STRA5 ;
DR   Q9AK82, DPO4_STRCO ;  A8AUV7, DPO4_STRGC ;  B4SIF5, DPO4_STRM5 ;
DR   B2FLR2, DPO4_STRMK ;  Q8DVR7, DPO4_STRMU ;  Q99Y66, DPO4_STRP1 ;
DR   Q04M21, DPO4_STRP2 ;  P0DA78, DPO4_STRP3 ;  Q5XA48, DPO4_STRP6 ;
DR   Q8NZI1, DPO4_STRP8 ;  Q1JA16, DPO4_STRPB ;  Q1JK63, DPO4_STRPC ;
DR   Q1JF59, DPO4_STRPD ;  Q1J509, DPO4_STRPF ;  A2RCQ1, DPO4_STRPG ;
DR   Q48RJ4, DPO4_STRPM ;  Q97SC7, DPO4_STRPN ;  P0DA79, DPO4_STRPQ ;
DR   Q8DQZ7, DPO4_STRR6 ;  A4VZ21, DPO4_STRS2 ;  A3CKU4, DPO4_STRSV ;
DR   Q5LYC2, DPO4_STRT1 ;  Q5M2Y5, DPO4_STRT2 ;  Q03J54, DPO4_STRTD ;
DR   Q4JB80, DPO4_SULAC ;  P96022, DPO4_SULSF ;  Q97W02, DPO4_SULSO ;
DR   Q974T8, DPO4_SULTO ;  Q67QM6, DPO4_SYMTH ;  P58965, DPO4_THETN ;
DR   Q73P36, DPO4_TREDE ;  B1AJ79, DPO4_UREP2 ;  Q9PQ53, DPO4_UREPA ;
DR   B5ZBT4, DPO4_UREU1 ;  A5F5Y1, DPO4_VIBC3 ;  Q9KPS5, DPO4_VIBCH ;
DR   C3LQ59, DPO4_VIBCM ;  Q87MB4, DPO4_VIBPA ;  Q8DBI7, DPO4_VIBVU ;
DR   Q7MID6, DPO4_VIBVY ;  Q8PGJ4, DPO4_XANAC ;  Q3BP42, DPO4_XANC5 ;
DR   Q4UQI2, DPO4_XANC8 ;  Q8PCW8, DPO4_XANCP ;  Q2P7M9, DPO4_XANOM ;
DR   P25615, DPO4_YEAST ;  A1JNY3, DPO4_YERE8 ;  A7FLI9, DPO4_YERP3 ;
DR   Q1C4D9, DPO4_YERPA ;  Q8ZBZ9, DPO4_YERPE ;  Q1CLD4, DPO4_YERPN ;
DR   A4TPK8, DPO4_YERPP ;  Q66DZ7, DPO4_YERPS ;  O60094, DPO5_SCHPO ;
DR   P39985, DPO5_YEAST ;  P28040, DPOA_SCHPO ;  P13382, DPOA_YEAST ;
DR   Q9LVN7, DPOD1_ARATH;  P28339, DPOD1_BOVIN;  P90829, DPOD1_CAEEL;
DR   Q54N97, DPOD1_DICDI;  P54358, DPOD1_DROME;  P28340, DPOD1_HUMAN;
DR   P97283, DPOD1_MESAU;  P52431, DPOD1_MOUSE;  Q9LRE6, DPOD1_ORYSJ;
DR   P30315, DPOD1_PLAFK;  O54747, DPOD1_RAT  ;  O48901, DPOD1_SOYBN;
DR   O48520, DPOD2_ARATH;  P49004, DPOD2_BOVIN;  Q19366, DPOD2_CAEEL;
DR   Q9W088, DPOD2_DROME;  P49005, DPOD2_HUMAN;  O35654, DPOD2_MOUSE;
DR   Q9LRE5, DPOD2_ORYSJ;  Q6AXY4, DPOD2_RAT  ;  P87324, DPOD2_SCHPO;
DR   O93610, DPOD2_XENLA;  P46957, DPOD2_YEAST;  P46588, DPOD_CANAL ;
DR   P30316, DPOD_SCHPO ;  P15436, DPOD_YEAST ;  Q54RD4, DPOE1_DICDI;
DR   Q07864, DPOE1_HUMAN;  Q9WVF7, DPOE1_MOUSE;  A7YWS7, DPOE2_BOVIN;
DR   Q19196, DPOE2_CAEEL;  Q5ZKQ6, DPOE2_CHICK;  Q54Y85, DPOE2_DICDI;
DR   P56282, DPOE2_HUMAN;  O54956, DPOE2_MOUSE;  Q3SZN5, DPOE3_BOVIN;
DR   Q75JQ9, DPOE3_DICDI;  Q9NRF9, DPOE3_HUMAN;  Q9JKP7, DPOE3_MOUSE;
DR   Q5R4W3, DPOE3_PONAB;  Q642A5, DPOE3_RAT  ;  A6QQ14, DPOE4_BOVIN;
DR   Q9NR33, DPOE4_HUMAN;  Q9CQ36, DPOE4_MOUSE;  Q752B8, DPOE_ASHGO ;
DR   Q4WXH8, DPOE_ASPFU ;  Q6FNY7, DPOE_CANGA ;  P0CN27, DPOE_CRYNB ;
DR   P0CN26, DPOE_CRYNJ ;  Q6BNG2, DPOE_DEBHA ;  O93845, DPOE_EMENI ;
DR   Q6CUS7, DPOE_KLULA ;  P87154, DPOE_SCHPO ;  Q4PFV5, DPOE_USTMA ;
DR   Q6C4J0, DPOE_YARLI ;  P21951, DPOE_YEAST ;  Q92076, DPOG1_CHICK;
DR   Q27607, DPOG1_DROME;  P54098, DPOG1_HUMAN;  P54099, DPOG1_MOUSE;
DR   Q9QYV8, DPOG1_RAT  ;  Q91684, DPOG1_XENLA;  Q0VC30, DPOG2_BOVIN;
DR   Q9UHN1, DPOG2_HUMAN;  Q9QZM2, DPOG2_MOUSE;  Q9W6G7, DPOG2_XENLA;
DR   Q9Y767, DPOG_NEUCR ;  Q01941, DPOG_PICPA ;  Q12704, DPOG_SCHPO ;
DR   P15801, DPOG_YEAST ;  O93745, DPOL1_AERPE;  P95690, DPOL1_SULAC;
DR   O50607, DPOL1_SULOH;  P26811, DPOL1_SULSO;  O93746, DPOL2_AERPE;
DR   Q07635, DPOL2_SULSO;  O05706, DPOL3_SULSH;  P95979, DPOL3_SULSO;
DR   Q9FHA3, DPOLA_ARATH;  Q54SV8, DPOLA_DICDI;  P26019, DPOLA_DROME;
DR   P09884, DPOLA_HUMAN;  O00874, DPOLA_LEIDO;  P33609, DPOLA_MOUSE;
DR   O48653, DPOLA_ORYSJ;  Q94636, DPOLA_OXYNO;  Q27152, DPOLA_OXYTR;
DR   O89042, DPOLA_RAT  ;  P27727, DPOLA_TRYBB;  Q9DE46, DPOLA_XENLA;
DR   Q27958, DPOLB_BOVIN;  Q6DRD3, DPOLB_DANRE;  P06746, DPOLB_HUMAN;
DR   Q8K409, DPOLB_MOUSE;  P06766, DPOLB_RAT  ;  O57383, DPOLB_XENLA;
DR   Q9UGP5, DPOLL_HUMAN;  Q4R380, DPOLL_MACFA;  Q9QXE2, DPOLL_MOUSE;
DR   Q5RKI3, DPOLL_RAT  ;  Q9NP87, DPOLM_HUMAN;  Q9JIW4, DPOLM_MOUSE;
DR   Q7Z5Q5, DPOLN_HUMAN;  Q7TQ07, DPOLN_MOUSE;  O75417, DPOLQ_HUMAN;
DR   P42494, DPOLX_ASFB7;  P0C986, DPOLX_ASFK5;  P0C984, DPOLX_ASFM2;
DR   P0C983, DPOLX_ASFP4;  P0C985, DPOLX_ASFWA;  Q7T6Y4, DPOLX_MIMIV;
DR   O60673, DPOLZ_HUMAN;  Q61493, DPOLZ_MOUSE;  A4ZU91, DPOL_ABVP  ;
DR   P03261, DPOL_ADE02 ;  P87503, DPOL_ADE04 ;  P04495, DPOL_ADE05 ;
DR   P05664, DPOL_ADE07 ;  P06538, DPOL_ADE12 ;  P48311, DPOL_ADE40 ;
DR   O72539, DPOL_ADEB2 ;  O72540, DPOL_ADEB3 ;  Q65946, DPOL_ADECC ;
DR   P87553, DPOL_ADECT ;  Q64751, DPOL_ADEG1 ;  Q88469, DPOL_ADET1 ;
DR   O36363, DPOL_ALHV1 ;  O29753, DPOL_ARCFU ;  P42489, DPOL_ASFB7 ;
DR   P0C974, DPOL_ASFK5 ;  P43139, DPOL_ASFL6 ;  P0C972, DPOL_ASFM2 ;
DR   P0C971, DPOL_ASFP4 ;  P0C973, DPOL_ASFWA ;  Q64898, DPOL_ASHV  ;
DR   Q9T1Q3, DPOL_BPAPS ;  Q37882, DPOL_BPB03 ;  Q37989, DPOL_BPCP1 ;
DR   P19894, DPOL_BPM2  ;  O64235, DPOL_BPMD2 ;  Q05254, DPOL_BPML5 ;
DR   P03680, DPOL_BPPH2 ;  P10479, DPOL_BPPRD ;  P06950, DPOL_BPPZA ;
DR   Q38087, DPOL_BPR69 ;  P30314, DPOL_BPSP1 ;  P06225, DPOL_BPSP2 ;
DR   P20311, DPOL_BPT3  ;  P04415, DPOL_BPT4  ;  P19822, DPOL_BPT5  ;
DR   P00581, DPOL_BPT7  ;  P30319, DPOL_CBEPV ;  A7U6F1, DPOL_CEV01 ;
DR   Q7SIG7, DPOL_DESST ;  P03162, DPOL_DHBV1 ;  P0C691, DPOL_DHBV3 ;
DR   Q66403, DPOL_DHBVQ ;  Q1HVC1, DPOL_EBVA8 ;  P03198, DPOL_EBVB9 ;
DR   Q3KSP1, DPOL_EBVG  ;  P28858, DPOL_EHV1B ;  Q6S6P1, DPOL_EHV1V ;
DR   P52367, DPOL_EHV2  ;  Q9DKT8, DPOL_ELHVK ;  P21402, DPOL_FOWPN ;
DR   Q6GZR5, DPOL_FRG3G ;  Q9E6N9, DPOL_GAHVM ;  Q69025, DPOL_GPCMV ;
DR   P03161, DPOL_GSHV  ;  P03158, DPOL_HBVA2 ;  P03159, DPOL_HBVA3 ;
DR   P17100, DPOL_HBVA4 ;  Q02314, DPOL_HBVA5 ;  Q91C36, DPOL_HBVA6 ;
DR   O91533, DPOL_HBVA7 ;  Q4R1S7, DPOL_HBVA8 ;  Q4R1R9, DPOL_HBVA9 ;
DR   P17394, DPOL_HBVB1 ;  P17393, DPOL_HBVB2 ;  Q9QAB8, DPOL_HBVB3 ;
DR   P17395, DPOL_HBVB4 ;  Q9PX62, DPOL_HBVB5 ;  Q67925, DPOL_HBVB6 ;
DR   Q9QBF1, DPOL_HBVB7 ;  P0C676, DPOL_HBVB8 ;  Q9E6S5, DPOL_HBVC0 ;
DR   P0C688, DPOL_HBVC1 ;  Q9YZR5, DPOL_HBVC2 ;  P12933, DPOL_HBVC3 ;
DR   P31870, DPOL_HBVC4 ;  P03157, DPOL_HBVC5 ;  Q913A7, DPOL_HBVC7 ;
DR   Q81165, DPOL_HBVC8 ;  P0C690, DPOL_HBVC9 ;  Q69028, DPOL_HBVCJ ;
DR   P12900, DPOL_HBVCP ;  P03155, DPOL_HBVD1 ;  P24024, DPOL_HBVD2 ;
DR   P03156, DPOL_HBVD3 ;  Q9QMI1, DPOL_HBVD4 ;  P0C679, DPOL_HBVD5 ;
DR   Q67878, DPOL_HBVD6 ;  O56655, DPOL_HBVD7 ;  Q69602, DPOL_HBVE1 ;
DR   Q80IU7, DPOL_HBVE2 ;  Q9QAW8, DPOL_HBVE3 ;  Q80IU4, DPOL_HBVE4 ;
DR   Q05486, DPOL_HBVF1 ;  Q8JMY4, DPOL_HBVF2 ;  Q99HS4, DPOL_HBVF3 ;
DR   Q99HR5, DPOL_HBVF4 ;  Q69605, DPOL_HBVF6 ;  Q8QZQ2, DPOL_HBVG2 ;
DR   Q9IBI4, DPOL_HBVG3 ;  P87744, DPOL_HBVGB ;  Q9YPV8, DPOL_HBVGO ;
DR   Q8JMY7, DPOL_HBVH1 ;  Q8JN08, DPOL_HBVH2 ;  Q8JMZ7, DPOL_HBVH3 ;
DR   Q9J5S2, DPOL_HBVOR ;  P08546, DPOL_HCMVA ;  P13846, DPOL_HHBV  ;
DR   P04293, DPOL_HHV11 ;  P07917, DPOL_HHV1A ;  P04292, DPOL_HHV1K ;
DR   P09854, DPOL_HHV1S ;  P07918, DPOL_HHV21 ;  P89453, DPOL_HHV2H ;
DR   P28857, DPOL_HHV6U ;  Q9QJ32, DPOL_HHV6Z ;  P52342, DPOL_HHV7J ;
DR   Q25BI3, DPOL_HIS1V ;  P17192, DPOL_HPBDB ;  P30028, DPOL_HPBDC ;
DR   P17193, DPOL_HPBDW ;  A4KX57, DPOL_HVAVE ;  P28859, DPOL_ICHVA ;
DR   Q196U0, DPOL_IIV3  ;  Q9QSK2, DPOL_IIV6  ;  Q58295, DPOL_METJA ;
DR   O27276, DPOL_METTH ;  P52025, DPOL_METVO ;  Q5UQR0, DPOL_MIMIV ;
DR   P27172, DPOL_MUHVS ;  P18131, DPOL_NPVAC ;  P41712, DPOL_NPVBM ;
DR   Q90162, DPOL_NPVCF ;  P30318, DPOL_NPVLD ;  Q83948, DPOL_NPVOP ;
DR   Q84173, DPOL_ORFN2 ;  Q6R7C9, DPOL_OSHVF ;  P30321, DPOL_PBCV1 ;
DR   P30320, DPOL_PBCVN ;  A7U6F2, DPOL_POV01 ;  A7U6F3, DPOL_PPV01 ;
DR   Q6UDK1, DPOL_PSHV1 ;  P0CL77, DPOL_PYRAB ;  P0CL76, DPOL_PYRAY ;
DR   P61875, DPOL_PYRFU ;  Q9HH06, DPOL_PYRGL ;  O59610, DPOL_PYRHO ;
DR   P77933, DPOL_PYRKO ;  Q51334, DPOL_PYRSD ;  P61876, DPOL_PYRWO ;
DR   Q85428, DPOL_RCMVM ;  O71121, DPOL_RHCM6 ;  O70736, DPOL_RSIV  ;
DR   Q779J8, DPOL_SFAVA ;  P24907, DPOL_SHV21 ;  O33845, DPOL_THEAG ;
DR   P74918, DPOL_THEFM ;  Q9HH84, DPOL_THEG8 ;  P56689, DPOL_THEGO ;
DR   Q9HH05, DPOL_THEHY ;  P30317, DPOL_THELI ;  Q56366, DPOL_THES9 ;
DR   Q4U3V0, DPOL_TNAVC ;  Q9YUS3, DPOL_TUHV1 ;  Q9YUS2, DPOL_TUHV2 ;
DR   O57191, DPOL_VACCA ;  P20509, DPOL_VACCC ;  P06856, DPOL_VACCW ;
DR   P33793, DPOL_VAR67 ;  P09252, DPOL_VZVD  ;  Q4JQU7, DPOL_VZVO  ;
DR   P03160, DPOL_WHV1  ;  P06275, DPOL_WHV2  ;  P12899, DPOL_WHV3  ;
DR   P12898, DPOL_WHV4  ;  P17396, DPOL_WHV5  ;  P11292, DPOL_WHV6  ;
DR   O71304, DPOL_WMHBV ;  P30322, DPOM_AGABT ;  P22374, DPOM_ASCIM ;
DR   P22373, DPOM_CLAPU ;  P10582, DPOM_MAIZE ;  P33537, DPOM_NEUCS ;
DR   P33538, DPOM_NEUIN ;  Q01529, DPOM_PODAS ;  Q9P6L6, DPOZ_SCHPO ;
DR   P14284, DPOZ_YEAST ;  P57520, HOLA_BUCAI ;  Q8K9B8, HOLA_BUCAP ;
DR   Q89AC0, HOLA_BUCBP ;  P28630, HOLA_ECOLI ;  P43747, HOLA_HAEIN ;
DR   P37540, HOLB_BACSU ;  P57435, HOLB_BUCAI ;  Q8K9J2, HOLB_BUCAP ;
DR   Q89AG8, HOLB_BUCBP ;  P28631, HOLB_ECOLI ;  P43748, HOLB_HAEIN ;
DR   P52024, HOLB_PSEAE ;  O69170, HOLB_YERPE ;  P28905, HOLC_ECOLI ;
DR   P43749, HOLC_HAEIN ;  O68823, HOLC_PSEAE ;  P28632, HOLD_ECOLI ;
DR   P43750, HOLD_HAEIN ;  P0ABT0, HOLE_ECO57 ;  P0ABS9, HOLE_ECOL6 ;
DR   P0ABS8, HOLE_ECOLI ;  P0ABT1, HOLE_SHIFL ;  Q5XG87, PAPD7_HUMAN;
DR   Q6PB75, PAPD7_MOUSE;  P63128, POK4_HUMAN ;  Q9Y253, POLH_HUMAN ;
DR   Q9JJN0, POLH_MOUSE ;  Q04049, POLH_YEAST ;  Q9UNA4, POLI_HUMAN ;
DR   Q6R3M4, POLI_MOUSE ;  P34409, POLK_CAEEL ;  Q9UBT6, POLK_HUMAN ;
DR   Q9QUG2, POLK_MOUSE ;  O74944, POLK_SCHPO ;  P94544, POLX_BACSU ;
DR   Q7SQ98, POL_ALV    ;  P03360, POL_AVIRE  ;  P19560, POL_BIV29  ;
DR   P25059, POL_BLVAU  ;  P03361, POL_BLVJ   ;  P31792, POL_FENV1  ;
DR   O93209, POL_FFV    ;  P14350, POL_FOAMV  ;  P03362, POL_HTL1A  ;
DR   P14078, POL_HTL1C  ;  P0C211, POL_HTL1L  ;  Q0R5R2, POL_HTL32  ;
DR   Q4U0X6, POL_HTL3P  ;  P03363, POL_HTLV2  ;  O93215, POL_HV190  ;
DR   O12158, POL_HV192  ;  O89290, POL_HV193  ;  Q9QBY3, POL_HV196  ;
DR   Q9QBZ9, POL_HV197  ;  O41798, POL_HV19N  ;  P03369, POL_HV1A2  ;
DR   Q77373, POL_HV1AN  ;  P03366, POL_HV1B1  ;  P04587, POL_HV1B5  ;
DR   Q73368, POL_HV1B9  ;  P03367, POL_HV1BR  ;  P04589, POL_HV1EL  ;
DR   Q75002, POL_HV1ET  ;  P04585, POL_HV1H2  ;  P20875, POL_HV1JR  ;
DR   P0C6F2, POL_HV1LW  ;  Q9QBZ1, POL_HV1M2  ;  P04588, POL_HV1MA  ;
DR   P05961, POL_HV1MN  ;  Q9QBZ5, POL_HV1MP  ;  Q79666, POL_HV1MV  ;
DR   P12497, POL_HV1N5  ;  P18802, POL_HV1ND  ;  P20892, POL_HV1OY  ;
DR   P05959, POL_HV1RH  ;  Q9WC54, POL_HV1S2  ;  Q9WC63, POL_HV1S9  ;
DR   O89940, POL_HV1SE  ;  P24740, POL_HV1U4  ;  Q9Q720, POL_HV1V9  ;
DR   Q9QSR3, POL_HV1VI  ;  P35963, POL_HV1Y2  ;  Q9IDV9, POL_HV1YB  ;
DR   O91080, POL_HV1YF  ;  P12499, POL_HV1Z2  ;  P18096, POL_HV2BE  ;
DR   P24107, POL_HV2CA  ;  P17757, POL_HV2D1  ;  P15833, POL_HV2D2  ;
DR   Q89928, POL_HV2EH  ;  P18042, POL_HV2G1  ;  Q74120, POL_HV2KR  ;
DR   P05962, POL_HV2NZ  ;  P04584, POL_HV2RO  ;  P12451, POL_HV2SB  ;
DR   P20876, POL_HV2ST  ;  Q76634, POL_HV2UC  ;  P04026, POL_IPHA   ;
DR   P11368, POL_IPMA   ;  P12894, POL_IPMAI  ;  Q82851, POL_JEMBR  ;
DR   P31623, POL_JSRV   ;  Q9TTC1, POL_KORV   ;  P03355, POL_MLVMS  ;
DR   P03365, POL_MMTVB  ;  P11283, POL_MMTVC  ;  P07572, POL_MPMV   ;
DR   P03354, POL_RSVP   ;  Q04095, POL_RSVSA  ;  O92956, POL_RSVSB  ;
DR   P23074, POL_SFV1   ;  P27401, POL_SFV3L  ;  Q87040, POL_SFVCP  ;
DR   P17283, POL_SIVCZ  ;  Q1A249, POL_SIVEK  ;  Q02836, POL_SIVG1  ;
DR   P22382, POL_SIVGB  ;  P05896, POL_SIVM1  ;  Q1A267, POL_SIVMB  ;
DR   P05897, POL_SIVMK  ;  P12502, POL_SIVS4  ;  P19505, POL_SIVSP  ;
DR   Q8AII1, POL_SIVTN  ;  P27973, POL_SIVV1  ;  P27980, POL_SIVVG  ;
DR   P05895, POL_SIVVT  ;  P03364, POL_SMRVH  ;  P04025, POL_SRV1   ;
DR   P51517, POL_SRV2   ;  O92815, POL_WDSV   ;  P03359, POL_WMSV   ;
DR   Q2F7J3, POL_XMRV3  ;  Q2F7J0, POL_XMRV4  ;  A1Z651, POL_XMRV6  ;
DR   Q07163, TY1AB_YEASX;  O13527, YA11B_YEAST;  Q09693, YA26_SCHPO ;
DR   Q12490, YB11B_YEAST;  Q12193, YB12B_YEAST;  Q12491, YB21B_YEAST;
DR   P25384, YC21B_YEAST;  Q03855, YD11B_YEAST;  Q99231, YD12B_YEAST;
DR   Q07793, YD13B_YEAST;  P0C2I2, YD14B_YEAST;  P0C2I3, YD15B_YEAST;
DR   Q12472, YD21B_YEAST;  Q03494, YD22B_YEAST;  Q07791, YD23B_YEAST;
DR   Q03612, YE11B_YEAST;  Q03619, YE12B_YEAST;  P0CX63, YF21B_YEAST;
DR   Q12141, YG11B_YEAST;  Q12269, YG12B_YEAST;  Q12316, YG13B_YEAST;
DR   Q12337, YG21B_YEAST;  P0CX64, YG22B_YEAST;  Q99315, YG31B_YEAST;
DR   O13535, YH11B_YEAST;  Q7LHG5, YI31B_YEAST;  P47098, YJ11B_YEAST;
DR   P47100, YJ12B_YEAST;  Q12088, YL11B_YEAST;  P0C2I5, YL12B_YEAST;
DR   P0C2I6, YL13B_YEAST;  P0C2I7, YL14B_YEAST;  P0C2J3, YL21B_YEAST;
DR   P0C2J5, YL22B_YEAST;  Q04711, YM11B_YEAST;  Q03434, YM12B_YEAST;
DR   Q04214, YM13B_YEAST;  Q04670, YM14B_YEAST;  Q12112, YN11B_YEAST;
DR   Q99337, YN12B_YEAST;  Q12273, YO11B_YEAST;  Q92393, YO12B_YEAST;
DR   Q12113, YO21B_YEAST;  Q12501, YO22B_YEAST;  O31902, YORL_BACSU ;
DR   Q12414, YP11B_YEAST;  P0C2I9, YP12B_YEAST;  P0C2J0, YP13B_YEAST;
DR   P0C2J1, YP14B_YEAST;
//
ID   2.7.7.8
DE   Polyribonucleotide nucleotidyltransferase.
AN   Polynucleotide phosphorylase.
CA   RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.
CC   -!- ADP, IDP, GDP, UDP and CDP can act as donors.
DR   A6TM00, PNP1_ALKMQ ;  A6TM05, PNP2_ALKMQ ;  A6TNZ5, PNP3_ALKMQ ;
DR   A6TRK1, PNP4_ALKMQ ;  Q8TCS8, PNPT1_HUMAN;  Q8K1R3, PNPT1_MOUSE;
DR   Q5RCW2, PNPT1_PONAB;  B0C1M5, PNP_ACAM1  ;  A9NGE2, PNP_ACHLI  ;
DR   A1TLL2, PNP_ACIAC  ;  Q6FF12, PNP_ACIAD  ;  B7H0Z1, PNP_ACIB3  ;
DR   B7I3U1, PNP_ACIB5  ;  B2I2Q0, PNP_ACIBC  ;  Q1IQ54, PNP_ACIBL  ;
DR   B0VLR7, PNP_ACIBS  ;  A3M1M7, PNP_ACIBT  ;  B0VEA3, PNP_ACIBY  ;
DR   A0LV20, PNP_ACIC1  ;  C1F8M1, PNP_ACIC5  ;  A5FVG2, PNP_ACICJ  ;
DR   B9MEL0, PNP_ACIET  ;  B7J4D8, PNP_ACIF2  ;  B5EMD4, PNP_ACIF5  ;
DR   A1W4L8, PNP_ACISJ  ;  A3MZU3, PNP_ACTP2  ;  B3GXC1, PNP_ACTP7  ;
DR   B0BUD5, PNP_ACTPJ  ;  A6VR10, PNP_ACTSZ  ;  A0KND9, PNP_AERHH  ;
DR   A4SJR9, PNP_AERS4  ;  B9JGS9, PNP_AGRRK  ;  A9CKQ7, PNP_AGRT5  ;
DR   B9JYL0, PNP_AGRVS  ;  B2UNA9, PNP_AKKM8  ;  Q0VSR7, PNP_ALCBS  ;
DR   Q0A7A1, PNP_ALHEH  ;  B6ENE6, PNP_ALISL  ;  A8MFB4, PNP_ALKOO  ;
DR   B3EU51, PNP_AMOA5  ;  B8JFZ1, PNP_ANAD2  ;  Q2IQ01, PNP_ANADE  ;
DR   A7H9F8, PNP_ANADF  ;  B9KIE3, PNP_ANAMF  ;  Q5PAY0, PNP_ANAMM  ;
DR   Q2GJV5, PNP_ANAPZ  ;  B4UHG5, PNP_ANASK  ;  B9MR54, PNP_ANATD  ;
DR   Q3M7Z9, PNP_ANAVT  ;  B7GG69, PNP_ANOFW  ;  O66593, PNP_AQUAE  ;
DR   A8EU19, PNP_ARCB4  ;  Q5NZR7, PNP_AROAE  ;  A1R525, PNP_ARTAT  ;
DR   B8HG67, PNP_ARTCA  ;  A0JUV8, PNP_ARTS2  ;  Q2NJ06, PNP_AYWBP  ;
DR   A8IGA3, PNP_AZOC5  ;  B6YRB0, PNP_AZOPC  ;  A1K7B5, PNP_AZOSB  ;
DR   C1DFK5, PNP_AZOVD  ;  A7Z4U0, PNP_BACA2  ;  C3P5L0, PNP_BACAA  ;
DR   C3L7C0, PNP_BACAC  ;  A0RHH8, PNP_BACAH  ;  Q81WM8, PNP_BACAN  ;
DR   B7JJ84, PNP_BACC0  ;  Q732R5, PNP_BACC1  ;  B7IUG5, PNP_BACC2  ;
DR   C1EP29, PNP_BACC3  ;  B7HDT0, PNP_BACC4  ;  B7HLE0, PNP_BACC7  ;
DR   A7GRD7, PNP_BACCN  ;  B9IV96, PNP_BACCQ  ;  Q819Z1, PNP_BACCR  ;
DR   Q636L9, PNP_BACCZ  ;  Q5L7Z7, PNP_BACFN  ;  Q64N73, PNP_BACFR  ;
DR   Q9KA83, PNP_BACHD  ;  Q6HF08, PNP_BACHK  ;  Q65JH5, PNP_BACLD  ;
DR   A8FDD7, PNP_BACP2  ;  Q5WFU8, PNP_BACSK  ;  P50849, PNP_BACSU  ;
DR   Q8A4N6, PNP_BACTN  ;  A6L0A5, PNP_BACV8  ;  A9VT44, PNP_BACWK  ;
DR   A1UU54, PNP_BARBK  ;  Q6G5F8, PNP_BARHE  ;  Q6G0P7, PNP_BARQU  ;
DR   A9IMR9, PNP_BART1  ;  Q1LSL2, PNP_BAUCH  ;  Q6MMS2, PNP_BDEBA  ;
DR   B2ICY4, PNP_BEII9  ;  C5BWR2, PNP_BEUC1  ;  B8DVV8, PNP_BIFA0  ;
DR   A1A008, PNP_BIFAA  ;  B3DPX0, PNP_BIFLD  ;  Q8G447, PNP_BIFLO  ;
DR   B7GNH2, PNP_BIFLS  ;  Q7VQM0, PNP_BLOFL  ;  Q493T3, PNP_BLOPB  ;
DR   Q2KWI6, PNP_BORA1  ;  Q0SM46, PNP_BORAP  ;  Q7WCQ0, PNP_BORBR  ;
DR   O51745, PNP_BORBU  ;  B7J0Q1, PNP_BORBZ  ;  B5RMZ9, PNP_BORDL  ;
DR   Q65ZW8, PNP_BORGA  ;  B2S1E9, PNP_BORHD  ;  Q7W570, PNP_BORPA  ;
DR   A9IGJ9, PNP_BORPD  ;  Q7VZU0, PNP_BORPE  ;  B5RQE3, PNP_BORRA  ;
DR   A1R0N0, PNP_BORT9  ;  C0R0E0, PNP_BRAHW  ;  Q89WB3, PNP_BRAJA  ;
DR   A5E870, PNP_BRASB  ;  A4YJF3, PNP_BRASO  ;  C0ZF43, PNP_BREBN  ;
DR   B2S9G0, PNP_BRUA1  ;  Q2YQR3, PNP_BRUA2  ;  Q57A96, PNP_BRUAB  ;
DR   A9M9Z8, PNP_BRUC2  ;  C0RG51, PNP_BRUMB  ;  Q8YEB7, PNP_BRUME  ;
DR   A5VTB6, PNP_BRUO2  ;  B0CK15, PNP_BRUSI  ;  Q8FXS9, PNP_BRUSU  ;
DR   B8D9F8, PNP_BUCA5  ;  P57454, PNP_BUCAI  ;  Q8K9H5, PNP_BUCAP  ;
DR   B8D7R0, PNP_BUCAT  ;  Q89AF8, PNP_BUCBP  ;  Q057K3, PNP_BUCCC  ;
DR   B1YTR1, PNP_BURA4  ;  Q1BV09, PNP_BURCA  ;  B1JVP5, PNP_BURCC  ;
DR   A0K927, PNP_BURCH  ;  B4E5M6, PNP_BURCJ  ;  Q0BDC6, PNP_BURCM  ;
DR   A9AJP0, PNP_BURM1  ;  A3MI97, PNP_BURM7  ;  A2S463, PNP_BURM9  ;
DR   Q62IN1, PNP_BURMA  ;  A1V2L2, PNP_BURMS  ;  A3NTA2, PNP_BURP0  ;
DR   Q3JUB3, PNP_BURP1  ;  A3N7L3, PNP_BURP6  ;  B2JDN2, PNP_BURP8  ;
DR   B2T2E3, PNP_BURPP  ;  Q63VN7, PNP_BURPS  ;  Q39EE1, PNP_BURS3  ;
DR   Q2SZN9, PNP_BURTA  ;  A4JGD4, PNP_BURVG  ;  Q142H7, PNP_BURXL  ;
DR   A4XL64, PNP_CALS8  ;  A7ZEX0, PNP_CAMC1  ;  A7GX79, PNP_CAMC5  ;
DR   A0RQD0, PNP_CAMFF  ;  A7I002, PNP_CAMHC  ;  A8FMV9, PNP_CAMJ8  ;
DR   A7H2C7, PNP_CAMJD  ;  Q0P903, PNP_CAMJE  ;  A1W0N8, PNP_CAMJJ  ;
DR   Q5HTK8, PNP_CAMJR  ;  B9KFM1, PNP_CAMLR  ;  Q3ABA6, PNP_CARHZ  ;
DR   B8GWZ0, PNP_CAUCN  ;  Q9AC32, PNP_CAUCR  ;  B0T175, PNP_CAUSK  ;
DR   B3PIA0, PNP_CELJU  ;  A9WEJ7, PNP_CHLAA  ;  Q5L5B4, PNP_CHLAB  ;
DR   B8G3Z1, PNP_CHLAD  ;  Q3APY4, PNP_CHLCH  ;  Q822C1, PNP_CHLCV  ;
DR   Q255L4, PNP_CHLFF  ;  B3EH06, PNP_CHLL2  ;  Q9PL77, PNP_CHLMU  ;
DR   B3QM09, PNP_CHLP8  ;  B3EMN6, PNP_CHLPB  ;  A1BDY1, PNP_CHLPD  ;
DR   Q9Z6R0, PNP_CHLPN  ;  B9LH03, PNP_CHLSY  ;  B0B971, PNP_CHLT2  ;
DR   B3QY14, PNP_CHLT3  ;  Q3KKJ7, PNP_CHLTA  ;  B0BAV0, PNP_CHLTB  ;
DR   Q8KBY3, PNP_CHLTE  ;  O84849, PNP_CHLTR  ;  Q1QSZ4, PNP_CHRSD  ;
DR   Q7NY10, PNP_CHRVO  ;  A8AQ53, PNP_CITK8  ;  A5CSN9, PNP_CLAM3  ;
DR   B0RGW7, PNP_CLAMS  ;  Q97I45, PNP_CLOAB  ;  A7FVY7, PNP_CLOB1  ;
DR   C3L0B0, PNP_CLOB6  ;  A6LSR0, PNP_CLOB8  ;  B2V4H5, PNP_CLOBA  ;
DR   B2TJ61, PNP_CLOBB  ;  A5I4I7, PNP_CLOBH  ;  C1FS53, PNP_CLOBJ  ;
DR   B1II43, PNP_CLOBK  ;  A7GG00, PNP_CLOBL  ;  B1KWK1, PNP_CLOBM  ;
DR   B8I2R5, PNP_CLOCE  ;  Q18BI4, PNP_CLOD6  ;  B9E1K8, PNP_CLOK1  ;
DR   A5N848, PNP_CLOK5  ;  A0Q0Q1, PNP_CLONN  ;  Q0TPS3, PNP_CLOP1  ;
DR   Q8XJS4, PNP_CLOPE  ;  A9KNK6, PNP_CLOPH  ;  Q0SSE0, PNP_CLOPS  ;
DR   Q895J3, PNP_CLOTE  ;  A3DCH7, PNP_CLOTH  ;  Q482T5, PNP_COLP3  ;
DR   B5Y8I4, PNP_COPPD  ;  C3PH09, PNP_CORA7  ;  Q6NGP1, PNP_CORDI  ;
DR   Q8FPB7, PNP_COREF  ;  A4QEY2, PNP_CORGB  ;  Q8NP50, PNP_CORGL  ;
DR   Q4JV61, PNP_CORJK  ;  C4LJ74, PNP_CORK4  ;  B1VDC1, PNP_CORU7  ;
DR   B6J6S7, PNP_COXB1  ;  B6J0K5, PNP_COXB2  ;  A9KFK6, PNP_COXBN  ;
DR   A9ND62, PNP_COXBR  ;  Q83D87, PNP_COXBU  ;  Q0KCT4, PNP_CUPNH  ;
DR   Q473U7, PNP_CUPPJ  ;  B3R3W3, PNP_CUPTR  ;  B1WQ52, PNP_CYAA5  ;
DR   B8HXN3, PNP_CYAP4  ;  B7KIQ3, PNP_CYAP7  ;  B7K339, PNP_CYAP8  ;
DR   Q11U61, PNP_CYTH3  ;  Q47D98, PNP_DECAR  ;  Q3Z7V6, PNP_DEHE1  ;
DR   A5FQT2, PNP_DEHSB  ;  Q3ZXV6, PNP_DEHSC  ;  C1CXB5, PNP_DEIDV  ;
DR   Q1J1D0, PNP_DEIGD  ;  Q9RSR1, PNP_DEIRA  ;  A9BNB8, PNP_DELAS  ;
DR   B8FCZ0, PNP_DESAA  ;  C0QHM6, PNP_DESAH  ;  B1I393, PNP_DESAP  ;
DR   B8J1X9, PNP_DESDA  ;  Q30WI5, PNP_DESDG  ;  B8FR00, PNP_DESHD  ;
DR   Q24UJ4, PNP_DESHY  ;  A8ZZ59, PNP_DESOH  ;  Q6AJY9, PNP_DESPS  ;
DR   A4J5W6, PNP_DESRM  ;  Q72ER6, PNP_DESVH  ;  B8DN07, PNP_DESVM  ;
DR   A1VG88, PNP_DESVV  ;  A5EXU0, PNP_DICNV  ;  B5YEB0, PNP_DICT6  ;
DR   B8E2S5, PNP_DICTD  ;  A8LKE7, PNP_DINSH  ;  A7ZS61, PNP_ECO24  ;
DR   B7UJ59, PNP_ECO27  ;  B7MB85, PNP_ECO45  ;  B7LH99, PNP_ECO55  ;
DR   Q8X9M3, PNP_ECO57  ;  B5YS54, PNP_ECO5E  ;  B7NKN3, PNP_ECO7I  ;
DR   B7N0U9, PNP_ECO81  ;  B7M072, PNP_ECO8A  ;  C4ZSQ5, PNP_ECOBW  ;
DR   B1XGX6, PNP_ECODH  ;  A8A4Y0, PNP_ECOHS  ;  A1AG69, PNP_ECOK1  ;
DR   Q0TCU5, PNP_ECOL5  ;  Q8FD87, PNP_ECOL6  ;  B1IQV7, PNP_ECOLC  ;
DR   P05055, PNP_ECOLI  ;  B7NDF0, PNP_ECOLU  ;  B6I1N9, PNP_ECOSE  ;
DR   B1LFR6, PNP_ECOSM  ;  Q1R6H4, PNP_ECOUT  ;  C5BFC1, PNP_EDWI9  ;
DR   Q3YSC4, PNP_EHRCJ  ;  Q2GGA4, PNP_EHRCR  ;  Q5FHK5, PNP_EHRRG  ;
DR   Q5HBH6, PNP_EHRRW  ;  B2KDX2, PNP_ELUMP  ;  A4WEX9, PNP_ENT38  ;
DR   Q82ZJ2, PNP_ENTFA  ;  A7MIN6, PNP_ENTS8  ;  Q6D9A1, PNP_ERWCT  ;
DR   B2VGN7, PNP_ERWT9  ;  Q2NBZ2, PNP_ERYLH  ;  B7LR33, PNP_ESCF3  ;
DR   B1YI57, PNP_EXIS2  ;  C4L6J6, PNP_EXISA  ;  A7HK24, PNP_FERNB  ;
DR   B0S1D9, PNP_FINM2  ;  A5FJZ1, PNP_FLAJ1  ;  A6H185, PNP_FLAPJ  ;
DR   Q0RDT1, PNP_FRAAA  ;  B0TZ09, PNP_FRAP2  ;  Q2J735, PNP_FRASC  ;
DR   A8L6G1, PNP_FRASN  ;  Q14IC9, PNP_FRAT1  ;  A7NDP3, PNP_FRATF  ;
DR   Q2A269, PNP_FRATH  ;  B2SDK7, PNP_FRATM  ;  A0Q5I9, PNP_FRATN  ;
DR   Q0BKU1, PNP_FRATO  ;  Q5NGX7, PNP_FRATT  ;  A4IZA6, PNP_FRATW  ;
DR   Q8RIA1, PNP_FUSNN  ;  C1A3Y1, PNP_GEMAT  ;  B5EI63, PNP_GEOBB  ;
DR   Q5L0I2, PNP_GEOKA  ;  B3EAF2, PNP_GEOLS  ;  Q39VA1, PNP_GEOMG  ;
DR   B9M1G5, PNP_GEOSF  ;  Q74CS9, PNP_GEOSL  ;  C6E2P5, PNP_GEOSM  ;
DR   C5D9D5, PNP_GEOSW  ;  A4IME3, PNP_GEOTN  ;  A5GF91, PNP_GEOUR  ;
DR   Q7NGM0, PNP_GLOVI  ;  A9HF35, PNP_GLUDA  ;  Q5FQL9, PNP_GLUOX  ;
DR   Q0BPK3, PNP_GRABC  ;  A0LYC0, PNP_GRAFK  ;  Q7VL91, PNP_HAEDU  ;
DR   Q4QNV7, PNP_HAEI8  ;  A5UAQ6, PNP_HAEIE  ;  A5UG34, PNP_HAEIG  ;
DR   P44584, PNP_HAEIN  ;  B8F492, PNP_HAEPS  ;  Q0I2T0, PNP_HAES1  ;
DR   B0UTJ5, PNP_HAES2  ;  Q2SMK9, PNP_HAHCH  ;  A1WXU7, PNP_HALHL  ;
DR   B8CW78, PNP_HALOH  ;  C4K3E6, PNP_HAMD5  ;  Q17VM4, PNP_HELAH  ;
DR   Q7VIL0, PNP_HELHP  ;  B0THS2, PNP_HELMI  ;  B6JN53, PNP_HELP2  ;
DR   B5Z8L0, PNP_HELPG  ;  Q1CS51, PNP_HELPH  ;  Q9ZK11, PNP_HELPJ  ;
DR   B2UUX6, PNP_HELPS  ;  O25812, PNP_HELPY  ;  A9B8G1, PNP_HERA2  ;
DR   A4G647, PNP_HERAR  ;  B4U6R7, PNP_HYDS0  ;  Q0BWM9, PNP_HYPNA  ;
DR   Q5QYE1, PNP_IDILO  ;  A6SY02, PNP_JANMA  ;  Q28K17, PNP_JANSC  ;
DR   A6W815, PNP_KINRD  ;  B5XSX9, PNP_KLEP3  ;  A6TEI3, PNP_KLEP7  ;
DR   B2GKI3, PNP_KOCRD  ;  Q9CEI6, PNP_LACLA  ;  A2RMS5, PNP_LACLM  ;
DR   Q02WZ5, PNP_LACLS  ;  C1D8W8, PNP_LARHH  ;  Q1MPL7, PNP_LAWIP  ;
DR   Q5X1C7, PNP_LEGPA  ;  A5IHU3, PNP_LEGPC  ;  Q5ZRV8, PNP_LEGPH  ;
DR   Q5WT40, PNP_LEGPL  ;  Q6AFQ2, PNP_LEIXX  ;  B0SH22, PNP_LEPBA  ;
DR   Q04U27, PNP_LEPBJ  ;  Q04ZJ9, PNP_LEPBL  ;  B0SQH8, PNP_LEPBP  ;
DR   B1Y823, PNP_LEPCP  ;  Q72NX7, PNP_LEPIC  ;  Q8F7J8, PNP_LEPIN  ;
DR   Q92C23, PNP_LISIN  ;  C1L2N7, PNP_LISMC  ;  Q71ZZ1, PNP_LISMF  ;
DR   B8DFZ6, PNP_LISMH  ;  Q8Y7F1, PNP_LISMO  ;  A0AID2, PNP_LISW6  ;
DR   B1HR13, PNP_LYSSC  ;  B9EBG0, PNP_MACCJ  ;  Q2VZQ4, PNP_MAGSA  ;
DR   A0LE14, PNP_MAGSM  ;  Q65VB0, PNP_MANSM  ;  A1U5Z6, PNP_MARAV  ;
DR   Q0AK62, PNP_MARMM  ;  A6VU33, PNP_MARMS  ;  Q11BC3, PNP_MESSB  ;
DR   B7KN55, PNP_METC4  ;  Q609C6, PNP_METCA  ;  A9W8P8, PNP_METEP  ;
DR   Q1GXD2, PNP_METFK  ;  B3DZ86, PNP_METI4  ;  B8IGX3, PNP_METNO  ;
DR   B1ZGS7, PNP_METPB  ;  A2SFM2, PNP_METPP  ;  B1LZQ1, PNP_METRJ  ;
DR   B0UEX5, PNP_METS4  ;  B8EP09, PNP_METSB  ;  B0JYC3, PNP_MICAN  ;
DR   C5C9U0, PNP_MICLC  ;  Q2RJL9, PNP_MOOTA  ;  A0QIW5, PNP_MYCA1  ;
DR   B1MD62, PNP_MYCA9  ;  Q7TXW0, PNP_MYCBO  ;  A1KMC6, PNP_MYCBP  ;
DR   C1AFP7, PNP_MYCBT  ;  A4TCH6, PNP_MYCGI  ;  B8ZQJ6, PNP_MYCLB  ;
DR   Q9CCF8, PNP_MYCLE  ;  B2HKV3, PNP_MYCMM  ;  Q73VX0, PNP_MYCPA  ;
DR   A0QVQ5, PNP_MYCS2  ;  A3PY93, PNP_MYCSJ  ;  A1UET6, PNP_MYCSK  ;
DR   Q1BA76, PNP_MYCSS  ;  A5U6D6, PNP_MYCTA  ;  O33325, PNP_MYCTU  ;
DR   A0PQE7, PNP_MYCUA  ;  A1T7L4, PNP_MYCVP  ;  Q1DAM1, PNP_MYXXD  ;
DR   B2A3A3, PNP_NATTJ  ;  Q5F9Q7, PNP_NEIG1  ;  B4RK29, PNP_NEIG2  ;
DR   A9M3J0, PNP_NEIM0  ;  A1IR09, PNP_NEIMA  ;  Q9K062, PNP_NEIMB  ;
DR   A1KT19, PNP_NEIMF  ;  Q2GEY8, PNP_NEOSM  ;  Q0AE53, PNP_NITEC  ;
DR   Q82XT0, PNP_NITEU  ;  Q1QS60, PNP_NITHX  ;  Q2Y5X9, PNP_NITMU  ;
DR   Q3J9C0, PNP_NITOC  ;  A6Q4N2, PNP_NITSB  ;  Q3SWP5, PNP_NITWN  ;
DR   Q5YSV6, PNP_NOCFA  ;  A1SLJ4, PNP_NOCSJ  ;  B2J2V3, PNP_NOSP7  ;
DR   Q8YP11, PNP_NOSS1  ;  Q2G5F5, PNP_NOVAD  ;  Q8EQT7, PNP_OCEIH  ;
DR   A6WWW1, PNP_OCHA4  ;  B6JCR8, PNP_OLICO  ;  Q6YQX2, PNP_ONYPE  ;
DR   B1ZS98, PNP_OPITP  ;  A5CC62, PNP_ORITB  ;  B3CTX1, PNP_ORITI  ;
DR   A6LFK9, PNP_PARD8  ;  A1B5P9, PNP_PARDP  ;  A7HZ97, PNP_PARL1  ;
DR   Q6MDI2, PNP_PARUW  ;  Q9CLU1, PNP_PASMU  ;  C6DKK7, PNP_PECCP  ;
DR   Q3A4A1, PNP_PELCD  ;  Q3B2E2, PNP_PELLD  ;  B4SDX4, PNP_PELPB  ;
DR   A1AMM6, PNP_PELPD  ;  A5D2S6, PNP_PELTS  ;  Q4FNM6, PNP_PELUB  ;
DR   C0QTM3, PNP_PERMH  ;  A9BH73, PNP_PETMO  ;  B4RC48, PNP_PHEZH  ;
DR   Q7MYZ0, PNP_PHOLL  ;  P41121, PNP_PHOLU  ;  Q6LUI8, PNP_PHOPR  ;
DR   B1VAN5, PNP_PHYAS  ;  B3QZG1, PNP_PHYMT  ;  A1VM56, PNP_POLNA  ;
DR   B1XUJ5, PNP_POLNS  ;  Q127W8, PNP_POLSJ  ;  A4SXQ7, PNP_POLSQ  ;
DR   B2RIW6, PNP_PORG3  ;  Q7MW79, PNP_PORGI  ;  B4S5G5, PNP_PROA2  ;
DR   Q6A7P6, PNP_PROAC  ;  A3PE40, PNP_PROM0  ;  A2C412, PNP_PROM1  ;
DR   A8G5Y9, PNP_PROM2  ;  A2C794, PNP_PROM3  ;  A9BBJ7, PNP_PROM4  ;
DR   A2BXQ9, PNP_PROM5  ;  Q319U4, PNP_PROM9  ;  Q7VAZ5, PNP_PROMA  ;
DR   B4F2C3, PNP_PROMH  ;  Q7V606, PNP_PROMM  ;  Q7V0R5, PNP_PROMP  ;
DR   A2BSA7, PNP_PROMS  ;  Q46JM7, PNP_PROMT  ;  A4SG26, PNP_PROVI  ;
DR   Q48E81, PNP_PSE14  ;  Q15VD4, PNP_PSEA6  ;  A6VCJ6, PNP_PSEA7  ;
DR   B7V1F2, PNP_PSEA8  ;  Q02FT2, PNP_PSEAB  ;  Q9HV59, PNP_PSEAE  ;
DR   Q1IF39, PNP_PSEE4  ;  Q4KIF2, PNP_PSEF5  ;  C3K255, PNP_PSEFS  ;
DR   Q3IJ73, PNP_PSEHT  ;  A4XYD6, PNP_PSEMY  ;  A5W983, PNP_PSEP1  ;
DR   Q3KI80, PNP_PSEPF  ;  B0KHX3, PNP_PSEPG  ;  Q88DW0, PNP_PSEPK  ;
DR   O87792, PNP_PSEPU  ;  B1J2B3, PNP_PSEPW  ;  Q87WQ8, PNP_PSESM  ;
DR   Q4ZNR6, PNP_PSEU2  ;  A4VPN6, PNP_PSEU5  ;  Q4FVL0, PNP_PSYA2  ;
DR   Q1QEN9, PNP_PSYCK  ;  A1ST53, PNP_PSYIN  ;  A5WBT2, PNP_PSYWF  ;
DR   Q1LPW7, PNP_RALME  ;  B2U7R6, PNP_RALPJ  ;  Q8XXP6, PNP_RALSO  ;
DR   A9WPX4, PNP_RENSM  ;  B3PXD7, PNP_RHIE6  ;  Q2KE00, PNP_RHIEC  ;
DR   Q1MN44, PNP_RHIL3  ;  Q98BI3, PNP_RHILO  ;  B5ZW24, PNP_RHILW  ;
DR   Q92SW0, PNP_RHIME  ;  C3MC71, PNP_RHISN  ;  Q7UR95, PNP_RHOBA  ;
DR   B6IVG3, PNP_RHOCS  ;  C0ZYB7, PNP_RHOE4  ;  Q21YD1, PNP_RHOFD  ;
DR   C1B324, PNP_RHOOB  ;  Q2J2J4, PNP_RHOP2  ;  Q07V82, PNP_RHOP5  ;
DR   Q6NCN8, PNP_RHOPA  ;  Q21C27, PNP_RHOPB  ;  Q13EM2, PNP_RHOPS  ;
DR   B3QAB0, PNP_RHOPT  ;  Q2RMR6, PNP_RHORT  ;  A3PNG0, PNP_RHOS1  ;
DR   Q3IYT7, PNP_RHOS4  ;  A4WWP0, PNP_RHOS5  ;  B9KP47, PNP_RHOSK  ;
DR   Q0S208, PNP_RHOSR  ;  C3PNK2, PNP_RICAE  ;  A8GNL8, PNP_RICAH  ;
DR   A8GWV2, PNP_RICB8  ;  Q1RIG0, PNP_RICBR  ;  A8EYU2, PNP_RICCK  ;
DR   Q92HV7, PNP_RICCN  ;  Q4ULK1, PNP_RICFE  ;  A8F1P3, PNP_RICM5  ;
DR   Q9ZD43, PNP_RICPR  ;  C4K0F4, PNP_RICPU  ;  B0BXR0, PNP_RICRO  ;
DR   A8GS96, PNP_RICRS  ;  Q68WN1, PNP_RICTY  ;  A7NPZ1, PNP_ROSCS  ;
DR   Q16CF6, PNP_ROSDO  ;  A5URV5, PNP_ROSS1  ;  Q1AW48, PNP_RUBXD  ;
DR   A1AWB1, PNP_RUTMC  ;  Q21H65, PNP_SACD2  ;  A4FM22, PNP_SACEN  ;
DR   A8M758, PNP_SALAI  ;  A9MP39, PNP_SALAR  ;  Q57JI3, PNP_SALCH  ;
DR   B5QZV4, PNP_SALEP  ;  B5REN2, PNP_SALG2  ;  Q5PL97, PNP_SALPA  ;
DR   A9N728, PNP_SALPB  ;  C0PZ50, PNP_SALPC  ;  B5BGJ1, PNP_SALPK  ;
DR   Q2S1P1, PNP_SALRD  ;  Q8Z3I0, PNP_SALTI  ;  A4X4P8, PNP_SALTO  ;
DR   Q8ZLT3, PNP_SALTY  ;  A8G911, PNP_SERP5  ;  A1S467, PNP_SHEAM  ;
DR   B8E6N7, PNP_SHEB2  ;  A3D7K1, PNP_SHEB5  ;  A6WRG3, PNP_SHEB8  ;
DR   A9KZW6, PNP_SHEB9  ;  Q12QG9, PNP_SHEDO  ;  Q086G7, PNP_SHEFN  ;
DR   B0TQ97, PNP_SHEHH  ;  A3QGU0, PNP_SHELP  ;  Q8EHL1, PNP_SHEON  ;
DR   A8H735, PNP_SHEPA  ;  A4Y9B5, PNP_SHEPC  ;  B8CKH8, PNP_SHEPW  ;
DR   A0KU01, PNP_SHESA  ;  A8FYR5, PNP_SHESH  ;  Q0HLF6, PNP_SHESM  ;
DR   Q0HXR0, PNP_SHESR  ;  A1RGY0, PNP_SHESW  ;  B1KRQ5, PNP_SHEWM  ;
DR   B2U211, PNP_SHIB3  ;  Q31W43, PNP_SHIBS  ;  Q32BG9, PNP_SHIDS  ;
DR   Q0T0B7, PNP_SHIF8  ;  Q83JG0, PNP_SHIFL  ;  Q3YX77, PNP_SHISS  ;
DR   Q5LN23, PNP_SILPO  ;  Q1GKK5, PNP_SILST  ;  A6UF34, PNP_SINMW  ;
DR   Q2NW19, PNP_SODGM  ;  Q01NW3, PNP_SOLUE  ;  A9F8Z2, PNP_SORC5  ;
DR   Q1GVQ8, PNP_SPHAL  ;  A5VCY9, PNP_SPHWW  ;  Q14LB9, PNP_SPICI  ;
DR   A7X1Q8, PNP_STAA1  ;  A6U193, PNP_STAA2  ;  Q2FHG4, PNP_STAA3  ;
DR   Q2FZ20, PNP_STAA8  ;  A5ISF8, PNP_STAA9  ;  Q2YXP2, PNP_STAAB  ;
DR   Q5HGF7, PNP_STAAC  ;  A6QGH3, PNP_STAAE  ;  Q99UJ8, PNP_STAAM  ;
DR   Q7A5X7, PNP_STAAN  ;  Q6GHG1, PNP_STAAR  ;  Q6G9T9, PNP_STAAS  ;
DR   A8Z3V4, PNP_STAAT  ;  Q8NWY9, PNP_STAAW  ;  B9DPE0, PNP_STACT  ;
DR   Q5HPR7, PNP_STAEQ  ;  Q8CST1, PNP_STAES  ;  Q4L5X7, PNP_STAHJ  ;
DR   Q49X62, PNP_STAS1  ;  Q3K3G9, PNP_STRA1  ;  Q8E7F6, PNP_STRA3  ;
DR   Q8E1Z8, PNP_STRA5  ;  Q53597, PNP_STRAT  ;  Q82K80, PNP_STRAW  ;
DR   Q8CJQ6, PNP_STRCO  ;  C0M913, PNP_STRE4  ;  B4U573, PNP_STREM  ;
DR   A8AV53, PNP_STRGC  ;  B1VXZ6, PNP_STRGG  ;  B4SQR6, PNP_STRM5  ;
DR   B2FN86, PNP_STRMK  ;  Q8DWB2, PNP_STRMU  ;  Q99XZ5, PNP_STRP1  ;
DR   Q04LT4, PNP_STRP2  ;  P0DD12, PNP_STRP3  ;  B5E2A0, PNP_STRP4  ;
DR   Q5X9W0, PNP_STRP6  ;  C1C5V9, PNP_STRP7  ;  Q8NZC6, PNP_STRP8  ;
DR   Q1J9S6, PNP_STRPB  ;  Q1JJX5, PNP_STRPC  ;  Q1JEW6, PNP_STRPD  ;
DR   Q1J4N2, PNP_STRPF  ;  A2RGH2, PNP_STRPG  ;  B1IAA9, PNP_STRPI  ;
DR   B8ZMC0, PNP_STRPJ  ;  Q48RA2, PNP_STRPM  ;  Q97S28, PNP_STRPN  ;
DR   P0DD13, PNP_STRPQ  ;  B2IMQ9, PNP_STRPS  ;  B5XIK4, PNP_STRPZ  ;
DR   Q8DQT0, PNP_STRR6  ;  A4W401, PNP_STRS2  ;  C0MFB1, PNP_STRS7  ;
DR   A3CQG6, PNP_STRSV  ;  A4VXQ4, PNP_STRSY  ;  Q5M1W9, PNP_STRT1  ;
DR   Q5M6F9, PNP_STRT2  ;  Q03MV9, PNP_STRTD  ;  B9DTE3, PNP_STRU0  ;
DR   C1CCW4, PNP_STRZJ  ;  C1CQ76, PNP_STRZT  ;  C1DTW6, PNP_SULAA  ;
DR   Q30TH2, PNP_SULDN  ;  A8Z660, PNP_SULMW  ;  A6QBH4, PNP_SULNB  ;
DR   B2V900, PNP_SULSY  ;  Q67P77, PNP_SYMTH  ;  Q2LWT4, PNP_SYNAS  ;
DR   Q31KE9, PNP_SYNE7  ;  A0LHM4, PNP_SYNFM  ;  Q2JQF4, PNP_SYNJA  ;
DR   Q2JLJ5, PNP_SYNJB  ;  B1XJU0, PNP_SYNP2  ;  Q5N1G4, PNP_SYNP6  ;
DR   A5GN19, PNP_SYNPW  ;  Q7U515, PNP_SYNPX  ;  A5GRD7, PNP_SYNR3  ;
DR   Q0I8D2, PNP_SYNS3  ;  Q3AV44, PNP_SYNS9  ;  Q3AM38, PNP_SYNSC  ;
DR   Q0AYI2, PNP_SYNWW  ;  P72659, PNP_SYNY3  ;  C5BPV5, PNP_TERTT  ;
DR   B7IE23, PNP_THEAB  ;  Q8DGW9, PNP_THEEB  ;  Q47RU5, PNP_THEFY  ;
DR   A8F725, PNP_THELT  ;  A6LNF5, PNP_THEM4  ;  Q9X166, PNP_THEMA  ;
DR   B9K8Y9, PNP_THENN  ;  A5IMM8, PNP_THEP1  ;  B0K9P4, PNP_THEP3  ;
DR   B0K1D0, PNP_THEPX  ;  B9KYR9, PNP_THERP  ;  B1LBY0, PNP_THESQ  ;
DR   Q72JJ8, PNP_THET2  ;  Q5SJ75, PNP_THET8  ;  Q9ZAE1, PNP_THETH  ;
DR   Q8RA43, PNP_THETN  ;  B5YHN2, PNP_THEYD  ;  Q31GJ9, PNP_THICR  ;
DR   Q3SKX5, PNP_THIDA  ;  B8GP06, PNP_THISH  ;  C4L8X0, PNP_TOLAT  ;
DR   Q73NW1, PNP_TREDE  ;  O83856, PNP_TREPA  ;  B2S4C3, PNP_TREPS  ;
DR   Q115K2, PNP_TRIEI  ;  Q820Y9, PNP_TROW8  ;  Q83G94, PNP_TROWT  ;
DR   B1GZG8, PNP_UNCTG  ;  C5CT24, PNP_VARPS  ;  A1WLP8, PNP_VEREI  ;
DR   A5CWW8, PNP_VESOH  ;  A5F913, PNP_VIBC3  ;  Q9KU76, PNP_VIBCH  ;
DR   C3LSQ2, PNP_VIBCM  ;  Q5E7L1, PNP_VIBF1  ;  B5FA83, PNP_VIBFM  ;
DR   A7MZI2, PNP_VIBHB  ;  Q87M06, PNP_VIBPA  ;  B7VJH3, PNP_VIBSL  ;
DR   Q8DBU9, PNP_VIBVU  ;  Q7MI20, PNP_VIBVY  ;  Q8D2Y0, PNP_WIGBR  ;
DR   Q73GN4, PNP_WOLPM  ;  B3CM21, PNP_WOLPP  ;  Q7M9I4, PNP_WOLSU  ;
DR   Q5GTR3, PNP_WOLTR  ;  C0R3T4, PNP_WOLWR  ;  Q8PJ59, PNP_XANAC  ;
DR   Q3BRP9, PNP_XANC5  ;  Q4UW98, PNP_XANC8  ;  B0RRB8, PNP_XANCB  ;
DR   Q8P7V1, PNP_XANCP  ;  Q2P0X5, PNP_XANOM  ;  B2SVJ9, PNP_XANOP  ;
DR   Q5GXV3, PNP_XANOR  ;  A7IC03, PNP_XANP2  ;  B2I730, PNP_XYLF2  ;
DR   Q9PGQ9, PNP_XYLFA  ;  B0U1R2, PNP_XYLFM  ;  Q87EV0, PNP_XYLFT  ;
DR   A1JIX3, PNP_YERE8  ;  O34275, PNP_YEREN  ;  A7FMR8, PNP_YERP3  ;
DR   Q1C3L8, PNP_YERPA  ;  B2K2Q9, PNP_YERPB  ;  Q0WBF9, PNP_YERPE  ;
DR   A9R5A9, PNP_YERPG  ;  Q1CM51, PNP_YERPN  ;  A4TQU4, PNP_YERPP  ;
DR   Q66F56, PNP_YERPS  ;  B1JLX6, PNP_YERPY  ;  Q5NQ32, PNP_ZYMMO  ;
//
ID   2.7.7.9
DE   UTP--glucose-1-phosphate uridylyltransferase.
AN   Glucose-1-phosphate uridylyltransferase.
AN   UDP-glucose diphosphorylase.
AN   UDP-glucose pyrophosphorylase.
CA   UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.
DR   Q54800, CAP3C_STRPN;  P58313, CAP4C_STRPN;  P27897, CELA_GLUXY ;
DR   P33696, EXON_RHIME ;  P0AAB7, GALF_ECO57 ;  P0AAB6, GALF_ECOLI ;
DR   Q48447, GALF_KLEPN ;  P0A2K8, GALF_SALTI ;  P0A2K7, GALF_SALTY ;
DR   P37776, GALF_SHIFL ;  Q59633, GALU2_PSEAE;  P0AEP5, GALU_ECO57 ;
DR   P0AEP4, GALU_ECOL6 ;  P0AEP3, GALU_ECOLI ;  Q9F664, GALU_HAEDU ;
DR   P44878, GALU_HAEIN ;  P47691, GALU_MYCGE ;  P75124, GALU_MYCPN ;
DR   Q9I291, GALU_PSEAE ;  P0AEP6, GALU_SHIFL ;  Q4A122, GTAB1_STAS1;
DR   Q49VP4, GTAB2_STAS1;  Q05852, GTAB_BACSU ;  Q2FE05, GTAB_STAA3 ;
DR   Q2G1T6, GTAB_STAA8 ;  Q2YW63, GTAB_STAAB ;  Q5HD54, GTAB_STAAC ;
DR   Q99RD4, GTAB_STAAM ;  Q7A3J9, GTAB_STAAN ;  Q6GDU6, GTAB_STAAR ;
DR   Q6G6H5, GTAB_STAAS ;  Q8NUU9, GTAB_STAAW ;  Q5HLD1, GTAB_STAEQ ;
DR   Q8CR67, GTAB_STAES ;  Q4L8Y7, GTAB_STAHJ ;  P0C0I9, HASC1_STRP1;
DR   P0DG70, HASC1_STRP3;  Q5XE04, HASC1_STRP6;  Q8NKW9, HASC1_STRP8;
DR   P0DG71, HASC1_STRPQ;  P67068, HASC2_STRP1;  P0DG72, HASC2_STRP3;
DR   Q5X9A7, HASC2_STRP6;  P67070, HASC2_STRP8;  P0DG73, HASC2_STRPQ;
DR   P0C0I8, HASC_STRPY ;  P57751, UGPA1_ARATH;  P08800, UGPA1_DICDI;
DR   Q8SSC5, UGPA1_ENCCU;  P78811, UGPA1_SCHPO;  P32861, UGPA1_YEAST;
DR   Q9M9P3, UGPA2_ARATH;  Q54YZ0, UGPA2_DICDI;  O59819, UGPA2_SCHPO;
DR   P38709, UGPA2_YEAST;  Q9LKG7, UGPA_ASTPN ;  Q07130, UGPA_BOVIN ;
DR   O35156, UGPA_CRIGR ;  Q43772, UGPA_HORVU ;  Q16851, UGPA_HUMAN ;
DR   Q91ZJ5, UGPA_MOUSE ;  Q9SDX3, UGPA_MUSAC ;  P79303, UGPA_PIG   ;
DR   O64459, UGPA_PYRPY ;  P19595, UGPA_SOLTU ;  Q58730, Y1334_METJA;
DR   O31822, YNGB_BACSU ;  P42407, YTDA_BACSU ;
//
ID   2.7.7.10
DE   UTP--hexose-1-phosphate uridylyltransferase.
AN   Gal-1-P uridylyltransferase.
AN   Galactose-1-phosphate uridylyltransferase.
CA   UTP + alpha-D-galactose 1-phosphate = diphosphate + UDP-galactose.
CC   -!- Alpha-D-glucose 1-phosphate can also act as acceptor, more slowly.
//
ID   2.7.7.11
DE   UTP--xylose-1-phosphate uridylyltransferase.
AN   Xylose-1-phosphate uridylyltransferase.
CA   UTP + alpha-D-xylose 1-phosphate = diphosphate + UDP-D-xylose.
//
ID   2.7.7.12
DE   UDP-glucose--hexose-1-phosphate uridylyltransferase.
AN   Gal-1-P uridylyltransferase.
AN   Galactose-1-phosphate uridylyltransferase.
AN   Hexose-1-phosphate uridylyltransferase.
AN   Uridyl transferase.
AN   Uridylyl removing enzyme.
CA   UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate
CA   + UDP-galactose.
PR   PROSITE; PDOC00108;
DR   P0CN77, GAL7_CRYNB ;  P0CN76, GAL7_CRYNJ ;  P09148, GAL7_ECOLI ;
DR   P31764, GAL7_HAEIN ;  P09580, GAL7_KLULA ;  Q7RYE7, GAL7_NEUCR ;
DR   P22714, GAL7_SALTY ;  Q9HDU5, GAL7_SCHPO ;  P13212, GAL7_STRLI ;
DR   O33836, GAL7_THEMA ;  Q96UI1, GAL7_TRIRE ;  P08431, GAL7_YEAST ;
DR   Q97P15, GALT1_STRPN;  Q8DNL8, GALT1_STRR6;  Q97NZ7, GALT2_STRPN;
DR   Q8DNK8, GALT2_STRR6;  Q9FK51, GALT_ARATH ;  Q9KDV2, GALT_BACHD ;
DR   P39575, GALT_BACSU ;  P45981, GALT_BUTFI ;  Q27536, GALT_CAEEL ;
DR   Q97EZ4, GALT_CLOAB ;  Q0TQU4, GALT_CLOP1 ;  Q8XKP8, GALT_CLOPE ;
DR   Q0ST91, GALT_CLOPS ;  Q9VMA2, GALT_DROME ;  Q836N8, GALT_ENTFA ;
DR   Q8RHC9, GALT_FUSNN ;  P07902, GALT_HUMAN ;  Q03BB6, GALT_LACC3 ;
DR   O84904, GALT_LACCA ;  B3W7I7, GALT_LACCB ;  Q00054, GALT_LACHE ;
DR   Q9CE63, GALT_LACLA ;  Q9S6S3, GALT_LACLM ;  Q02WH3, GALT_LACLS ;
DR   Q88SF0, GALT_LACPL ;  Q1WUZ2, GALT_LACS1 ;  Q93MM1, GALT_LACSS ;
DR   Q03249, GALT_MOUSE ;  Q03HL3, GALT_PEDPA ;  P43424, GALT_RAT   ;
DR   Q9RGR9, GALT_STACT ;  Q49ZK0, GALT_STAS1 ;  P96994, GALT_STRMU ;
DR   B5E1W4, GALT_STRP4 ;  B1I863, GALT_STRPI ;  B2ISV1, GALT_STRPS ;
DR   Q8VS92, GALT_STRSL ;  Q5LYY8, GALT_STRT1 ;  Q5M3K1, GALT_STRT2 ;
DR   Q9ZB09, GALT_STRTR ;  C1CMG3, GALT_STRZP ;  Q8R8R6, GALT_THETN ;
//
ID   2.7.7.13
DE   Mannose-1-phosphate guanylyltransferase.
AN   GDP-mannose pyrophosphorylase.
AN   GTP-mannose-1-phosphate guanylyltransferase.
CA   GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose.
CC   -!- The bacterial enzyme can also use ITP and dGTP as donors.
DR   P07874, ALGA_PSEAE ;  P59785, ALGA_PSEFL ;  Q88ND5, ALGA_PSEPK ;
DR   Q887Q9, ALGA_PSESM ;  Q6GMK8, GMPAA_DANRE;  Q6DKE9, GMPAA_XENLA;
DR   Q7SXP8, GMPAB_DANRE;  Q66KG5, GMPAB_XENLA;  Q68EY9, GMPBA_XENLA;
DR   A2VD83, GMPBB_XENLA;  O22287, GMPP1_ARATH;  Q84JH5, GMPP1_ORYSJ;
DR   Q9M2S0, GMPP2_ARATH;  Q941T9, GMPP2_ORYSJ;  Q8H1Q7, GMPP3_ARATH;
DR   Q6Z9A3, GMPP3_ORYSJ;  Q86HG0, GMPPA_DICDI;  Q96IJ6, GMPPA_HUMAN;
DR   Q922H4, GMPPA_MOUSE;  B0CM52, GMPPA_PAPAN;  Q5XIC1, GMPPA_RAT  ;
DR   Q0VFM6, GMPPA_XENTR;  Q2YDJ9, GMPPB_BOVIN;  Q61S97, GMPPB_CAEBR;
DR   A3QMC8, GMPPB_CAEEL;  Q6DBU5, GMPPB_DANRE;  Q54K39, GMPPB_DICDI;
DR   Q7JZB4, GMPPB_DROME;  Q295Y7, GMPPB_DROPS;  Q9Y5P6, GMPPB_HUMAN;
DR   Q8BTZ7, GMPPB_MOUSE;  P0C5I2, GMPPB_PIG  ;  Q68EQ1, GMPPB_XENTR;
DR   Q8X7P1, MANC1_ECO57;  O85342, MANC2_ECO57;  P37741, MANC7_ECOLX;
DR   P37753, MANC9_ECOLX;  P24174, MANC_ECOLI ;  Q48462, MANC_KLEPN ;
DR   Q01410, MANC_SALMO ;  P26340, MANC_SALTY ;  Q9Y725, MPG11_CANGA;
DR   Q6FRY2, MPG12_CANGA;  Q752H4, MPG1_ASHGO ;  Q4U3E8, MPG1_ASPFU ;
DR   Q2UJU5, MPG1_ASPOR ;  O93827, MPG1_CANAL ;  P0CO21, MPG1_CRYNB ;
DR   P0CO20, MPG1_CRYNJ ;  Q6BN12, MPG1_DEBHA ;  Q5B1J4, MPG1_EMENI ;
DR   Q4I1Y5, MPG1_GIBZE ;  Q70SJ2, MPG1_KLULA ;  Q7RVR8, MPG1_NEUCR ;
DR   Q9P8N0, MPG1_PICAN ;  O74484, MPG1_SCHPO ;  P37820, MPG1_SULAC ;
DR   O74624, MPG1_TRIRE ;  Q6CCU3, MPG1_YARLI ;  P41940, MPG1_YEAST ;
DR   P55357, NOEJ_RHISN ;  Q07024, RFBA_VIBCH ;  Q00473, RFBM_SALMU ;
DR   P26404, RFBM_SALTY ;  B0RVK6, XANB_XANCB ;  P0C7J3, XANB_XANCP ;
DR   O60064, YBB2_SCHPO ;
//
ID   2.7.7.14
DE   Ethanolamine-phosphate cytidylyltransferase.
AN   CTP:phosphoethanolamine cytidylyltransferase.
AN   Phosphorylethanolamine transferase.
CA   CTP + ethanolamine phosphate = diphosphate + CDP-ethanolamine.
DR   Q8SQW6, ECT1_ENCCU ;  Q9UTI6, ECT1_SCHPO ;  P33412, ECT1_YEAST ;
DR   Q5EA75, PCY2_BOVIN ;  Q55BZ4, PCY2_DICDI ;  Q99447, PCY2_HUMAN ;
DR   Q922E4, PCY2_MOUSE ;  O88637, PCY2_RAT   ;
//
ID   2.7.7.15
DE   Choline-phosphate cytidylyltransferase.
AN   CTP:phosphocholine cytidylyltransferase.
AN   Phosphorylcholine transferase.
CA   CTP + choline phosphate = diphosphate + CDP-choline.
DR   P49584, PCY1A_CRIGR;  P49585, PCY1A_HUMAN;  P49586, PCY1A_MOUSE;
DR   P19836, PCY1A_RAT  ;  Q9Y5K3, PCY1B_HUMAN;  Q811Q9, PCY1B_MOUSE;
DR   Q9QZC4, PCY1B_RAT  ;  P49583, PCY1_CAEEL ;  P49587, PCY1_PLAFK ;
DR   O74975, PCY1_SCHPO ;  P13259, PCY1_YEAST ;
//
ID   2.7.7.16
DE   Transferred entry: 3.1.27.5.
//
ID   2.7.7.17
DE   Transferred entry: 3.1.27.1.
//
ID   2.7.7.18
DE   Nicotinate-nucleotide adenylyltransferase.
AN   Deamido-NAD(+) diphosphorylase.
AN   Deamido-NAD(+) pyrophosphorylase.
CA   ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD(+).
DR   A9NFP5, NADD_ACHLI ;  A0LSX5, NADD_ACIC1 ;  B7J9S1, NADD_ACIF2 ;
DR   B5EPW0, NADD_ACIF5 ;  A0KN91, NADD_AERHH ;  A4SJW5, NADD_AERS4 ;
DR   Q8UBS2, NADD_AGRT5 ;  B8J538, NADD_ANAD2 ;  Q2IKJ8, NADD_ANADE ;
DR   B4UJX6, NADD_ANASK ;  B9MRP6, NADD_ANATD ;  Q3MAP9, NADD_ANAVT ;
DR   O66452, NADD_AQUAE ;  A8EWM2, NADD_ARCB4 ;  A1R783, NADD_ARTAT ;
DR   A0JXJ4, NADD_ARTS2 ;  B6YR44, NADD_AZOPC ;  A7Z6X8, NADD_BACA2 ;
DR   C3P8N9, NADD_BACAA ;  C3L5T6, NADD_BACAC ;  A0RIU9, NADD_BACAH ;
DR   B7JNW4, NADD_BACC0 ;  Q730K3, NADD_BACC1 ;  B7IYI5, NADD_BACC2 ;
DR   C1ESM6, NADD_BACC3 ;  B7HCV9, NADD_BACC4 ;  B7HPN1, NADD_BACC7 ;
DR   A7GT26, NADD_BACCN ;  B9IY99, NADD_BACCQ ;  Q818D2, NADD_BACCR ;
DR   Q634L0, NADD_BACCZ ;  Q5L9N8, NADD_BACFN ;  Q64PY0, NADD_BACFR ;
DR   Q9KD91, NADD_BACHD ;  Q6HDJ0, NADD_BACHK ;  Q65H36, NADD_BACLD ;
DR   A8FFF0, NADD_BACP2 ;  Q5WHI0, NADD_BACSK ;  P54455, NADD_BACSU ;
DR   Q8A675, NADD_BACTN ;  A6L0W0, NADD_BACV8 ;  A9VHV9, NADD_BACWK ;
DR   Q1LTM7, NADD_BAUCH ;  Q2KYV6, NADD_BORA1 ;  Q0SM71, NADD_BORAP ;
DR   Q7WL81, NADD_BORBR ;  O51723, NADD_BORBU ;  B7J0M8, NADD_BORBZ ;
DR   Q65ZZ2, NADD_BORGA ;  B2S1C4, NADD_BORHD ;  Q7W7U1, NADD_BORPA ;
DR   A9ITN0, NADD_BORPD ;  Q7VWE6, NADD_BORPE ;  A1R0K5, NADD_BORT9 ;
DR   Q89X84, NADD_BRAJA ;  A5E960, NADD_BRASB ;  A4YKF0, NADD_BRASO ;
DR   Q2YLI8, NADD_BRUA2 ;  Q57B48, NADD_BRUAB ;  Q8YJ77, NADD_BRUME ;
DR   Q8CY36, NADD_BRUSU ;  B8D9M4, NADD_BUCA5 ;  P57521, NADD_BUCAI ;
DR   Q8K9B7, NADD_BUCAP ;  B8D7X6, NADD_BUCAT ;  B4E5R9, NADD_BURCJ ;
DR   Q39E98, NADD_BURS3 ;  A4XKG5, NADD_CALS8 ;  A0RQT6, NADD_CAMFF ;
DR   A8FN79, NADD_CAMJ8 ;  Q9PMQ3, NADD_CAMJE ;  A1W118, NADD_CAMJJ ;
DR   Q5HT13, NADD_CAMJR ;  Q3AF34, NADD_CARHZ ;  B0T316, NADD_CAUSK ;
DR   B3PKM9, NADD_CELJU ;  Q3ANY3, NADD_CHLCH ;  B3EIJ2, NADD_CHLL2 ;
DR   B3QLU8, NADD_CHLP8 ;  B3EQ84, NADD_CHLPB ;  A1BJW0, NADD_CHLPD ;
DR   B3QYZ5, NADD_CHLT3 ;  Q8KGF2, NADD_CHLTE ;  Q1QXB3, NADD_CHRSD ;
DR   Q7P0P7, NADD_CHRVO ;  A8AJG3, NADD_CITK8 ;  A5CR36, NADD_CLAM3 ;
DR   B0RDF9, NADD_CLAMS ;  Q97JL2, NADD_CLOAB ;  A7FXU4, NADD_CLOB1 ;
DR   C3L3J1, NADD_CLOB6 ;  A6LQS1, NADD_CLOB8 ;  B2V0B0, NADD_CLOBA ;
DR   B2TKI3, NADD_CLOBB ;  A5I664, NADD_CLOBH ;  C1FVW3, NADD_CLOBJ ;
DR   B1ILY3, NADD_CLOBK ;  A7GHK0, NADD_CLOBL ;  B1KZR1, NADD_CLOBM ;
DR   B9E022, NADD_CLOK1 ;  A5N6K3, NADD_CLOK5 ;  A0Q1T2, NADD_CLONN ;
DR   Q0TNI7, NADD_CLOP1 ;  Q8XIJ4, NADD_CLOPE ;  A9KMF3, NADD_CLOPH ;
DR   Q0SR56, NADD_CLOPS ;  Q892N9, NADD_CLOTE ;  A3DEU4, NADD_CLOTH ;
DR   B5Y804, NADD_COPPD ;  Q8FN90, NADD_COREF ;  Q8NN57, NADD_CORGL ;
DR   Q4JWT1, NADD_CORJK ;  C4LJU0, NADD_CORK4 ;  A9KCQ7, NADD_COXBN ;
DR   A9NC46, NADD_COXBR ;  Q83DY4, NADD_COXBU ;  Q11XI1, NADD_CYTH3 ;
DR   Q47JQ3, NADD_DECAR ;  Q3ZAJ1, NADD_DEHE1 ;  A5FP50, NADD_DEHSB ;
DR   Q3ZW88, NADD_DEHSC ;  B8FMU1, NADD_DESAA ;  C6BSC2, NADD_DESAD ;
DR   B8FUR7, NADD_DESHD ;  Q24SP2, NADD_DESHY ;  Q6AK10, NADD_DESPS ;
DR   B5YEQ0, NADD_DICT6 ;  B8E0B1, NADD_DICTD ;  A8LR16, NADD_DINSH ;
DR   A7ZJ28, NADD_ECO24 ;  B7MFR2, NADD_ECO45 ;  Q8XBP0, NADD_ECO57 ;
DR   B5YQJ1, NADD_ECO5E ;  B7NLZ8, NADD_ECO7I ;  B7M5G6, NADD_ECO8A ;
DR   A7ZXR5, NADD_ECOHS ;  A1A8R4, NADD_ECOK1 ;  Q0TK34, NADD_ECOL5 ;
DR   Q8FJZ1, NADD_ECOL6 ;  B1IYG9, NADD_ECOLC ;  P0A752, NADD_ECOLI ;
DR   B7N9P5, NADD_ECOLU ;  B6I150, NADD_ECOSE ;  B1LL88, NADD_ECOSM ;
DR   Q830B9, NADD_ENTFA ;  A7MQS3, NADD_ENTS8 ;  Q6D7L9, NADD_ERWCT ;
DR   Q2N6F4, NADD_ERYLH ;  B7LLH4, NADD_ESCF3 ;  B1YKR5, NADD_EXIS2 ;
DR   A7HJZ9, NADD_FERNB ;  A5FLZ0, NADD_FLAJ1 ;  A6GVY8, NADD_FLAPJ ;
DR   Q0RPE7, NADD_FRAAA ;  Q2JDN2, NADD_FRASC ;  Q8REH1, NADD_FUSNN ;
DR   C1A4H9, NADD_GEMAT ;  B5EEI3, NADD_GEOBB ;  Q5KWX9, NADD_GEOKA ;
DR   B3E3R0, NADD_GEOLS ;  Q39QR1, NADD_GEOMG ;  B9M0D7, NADD_GEOSF ;
DR   Q747Q5, NADD_GEOSL ;  C6E7L8, NADD_GEOSM ;  C5D4W0, NADD_GEOSW ;
DR   A4IR49, NADD_GEOTN ;  A5G905, NADD_GEOUR ;  Q7NE64, NADD_GLOVI ;
DR   A9HC14, NADD_GLUDA ;  Q5FRT1, NADD_GLUOX ;  A0M6X6, NADD_GRAFK ;
DR   Q2SA28, NADD_HAHCH ;  A1WYZ3, NADD_HALHL ;  Q7VJ92, NADD_HELHP ;
DR   B6JNH4, NADD_HELP2 ;  Q1CRS1, NADD_HELPH ;  Q9ZJP8, NADD_HELPJ ;
DR   O25895, NADD_HELPY ;  A9AXY4, NADD_HERA2 ;  A4G2M4, NADD_HERAR ;
DR   B4U7J9, NADD_HYDS0 ;  Q5QYC8, NADD_IDILO ;  A6WDM4, NADD_KINRD ;
DR   B5XZR5, NADD_KLEP3 ;  A6T6A0, NADD_KLEP7 ;  Q9CGJ7, NADD_LACLA ;
DR   Q88WT5, NADD_LACPL ;  C1DA26, NADD_LARHH ;  Q5X5M1, NADD_LEGPA ;
DR   A5IBI8, NADD_LEGPC ;  Q5ZVU5, NADD_LEGPH ;  Q5WX01, NADD_LEGPL ;
DR   Q6AFX7, NADD_LEIXX ;  Q04Q93, NADD_LEPBJ ;  Q054P9, NADD_LEPBL ;
DR   Q72NR0, NADD_LEPIC ;  Q8F7T9, NADD_LEPIN ;  Q92BM5, NADD_LISIN ;
DR   C1KVD5, NADD_LISMC ;  Q71ZI2, NADD_LISMF ;  B8DE23, NADD_LISMH ;
DR   Q8Y735, NADD_LISMO ;  A0AIT7, NADD_LISW6 ;  A1U3C2, NADD_MARAV ;
DR   A6VZ84, NADD_MARMS ;  B7KS48, NADD_METC4 ;  Q606Y2, NADD_METCA ;
DR   A9W6Q3, NADD_METEP ;  B3DVR2, NADD_METI4 ;  A2SFG3, NADD_METPP ;
DR   Q2RKZ5, NADD_MOOTA ;  A0QDI7, NADD_MYCA1 ;  Q7TYM1, NADD_MYCBO ;
DR   A1KLB3, NADD_MYCBP ;  A4T2H9, NADD_MYCGI ;  Q9CBZ8, NADD_MYCLE ;
DR   B2HME5, NADD_MYCMM ;  Q73XR5, NADD_MYCPA ;  A0R112, NADD_MYCS2 ;
DR   A3Q2D5, NADD_MYCSJ ;  A1UIY9, NADD_MYCSK ;  Q1B647, NADD_MYCSS ;
DR   A5U5B6, NADD_MYCTA ;  O86328, NADD_MYCTU ;  A1TC03, NADD_MYCVP ;
DR   Q1D4R3, NADD_MYXXD ;  Q5F556, NADD_NEIG1 ;  B4RR84, NADD_NEIG2 ;
DR   A9M0D0, NADD_NEIM0 ;  P57089, NADD_NEIMA ;  P57090, NADD_NEIMB ;
DR   A1KWA2, NADD_NEIMF ;  A6Q541, NADD_NITSB ;  A1SHP7, NADD_NOCSJ ;
DR   Q8YM77, NADD_NOSS1 ;  Q8EPV1, NADD_OCEIH ;  B1ZVV8, NADD_OPITP ;
DR   A6L8D1, NADD_PARD8 ;  A7HT64, NADD_PARL1 ;  Q3A1E1, NADD_PELCD ;
DR   Q3B146, NADD_PELLD ;  B4SH35, NADD_PELPB ;  A1AV35, NADD_PELPD ;
DR   Q4FP43, NADD_PELUB ;  A9BK06, NADD_PETMO ;  B2RMD0, NADD_PORG3 ;
DR   Q7MXU9, NADD_PORGI ;  B4S6D9, NADD_PROA2 ;  A4SGY4, NADD_PROVI ;
DR   Q15VK3, NADD_PSEA6 ;  A6V0A4, NADD_PSEA7 ;  B7V8A6, NADD_PSEA8 ;
DR   Q02SH3, NADD_PSEAB ;  Q9HX21, NADD_PSEAE ;  Q1I4F1, NADD_PSEE4 ;
DR   Q4K5G0, NADD_PSEF5 ;  A4XYY3, NADD_PSEMY ;  B0KJY4, NADD_PSEPG ;
DR   Q88DL5, NADD_PSEPK ;  B1J134, NADD_PSEPW ;  Q87VV7, NADD_PSESM ;
DR   Q4ZN74, NADD_PSEU2 ;  A1SU57, NADD_PSYIN ;  B3PRZ6, NADD_RHIE6 ;
DR   Q2K2X3, NADD_RHIEC ;  Q1MA73, NADD_RHIL3 ;  Q98EZ6, NADD_RHILO ;
DR   B5ZUE6, NADD_RHILW ;  Q92LB1, NADD_RHIME ;  Q7UFN6, NADD_RHOBA ;
DR   Q21WQ0, NADD_RHOFD ;  A3PLX6, NADD_RHOS1 ;  Q3J0C4, NADD_RHOS4 ;
DR   A4WPT1, NADD_RHOS5 ;  B9KKZ0, NADD_RHOSK ;  A7NPC0, NADD_ROSCS ;
DR   Q16AV3, NADD_ROSDO ;  A5UVE4, NADD_ROSS1 ;  Q1AVU4, NADD_RUBXD ;
DR   Q21FD0, NADD_SACD2 ;  A4F9M5, NADD_SACEN ;  A8M0Y6, NADD_SALAI ;
DR   A9MKD1, NADD_SALAR ;  Q57RT0, NADD_SALCH ;  B5QVP6, NADD_SALEP ;
DR   B5R7Z3, NADD_SALG2 ;  Q5PM85, NADD_SALPA ;  A9MUK6, NADD_SALPB ;
DR   B5BCE9, NADD_SALPK ;  Q2S0V3, NADD_SALRD ;  Q8Z8H7, NADD_SALTI ;
DR   A4XAF6, NADD_SALTO ;  Q8ZQZ8, NADD_SALTY ;  A8GB18, NADD_SERP5 ;
DR   A1S8T1, NADD_SHEAM ;  B8E4X4, NADD_SHEB2 ;  A3D7N9, NADD_SHEB5 ;
DR   A6WRK2, NADD_SHEB8 ;  A9L004, NADD_SHEB9 ;  Q12R42, NADD_SHEDO ;
DR   Q087K5, NADD_SHEFN ;  B0TR47, NADD_SHEHH ;  Q8CX46, NADD_SHEON ;
DR   A8H7C5, NADD_SHEPA ;  A4Y9F2, NADD_SHEPC ;  A0KTW4, NADD_SHESA ;
DR   A8FZ13, NADD_SHESH ;  Q0HLJ3, NADD_SHESM ;  Q0HXU7, NADD_SHESR ;
DR   A1RGU2, NADD_SHESW ;  B1KDW3, NADD_SHEWM ;  B2TU80, NADD_SHIB3 ;
DR   Q324Q5, NADD_SHIBS ;  Q32IU2, NADD_SHIDS ;  Q0T6P9, NADD_SHIF8 ;
DR   P0A753, NADD_SHIFL ;  Q3Z4F3, NADD_SHISS ;  Q5LW93, NADD_SILPO ;
DR   Q1GEC6, NADD_SILST ;  Q2NUV0, NADD_SODGM ;  Q01X27, NADD_SOLUE ;
DR   A7X2Z9, NADD_STAA1 ;  A6U266, NADD_STAA2 ;  Q2FGD0, NADD_STAA3 ;
DR   Q2FXY3, NADD_STAA8 ;  A5ITC1, NADD_STAA9 ;  Q2YT34, NADD_STAAB ;
DR   Q5HFG7, NADD_STAAC ;  A6QHD6, NADD_STAAE ;  P65501, NADD_STAAM ;
DR   P65502, NADD_STAAN ;  Q6GGA7, NADD_STAAR ;  Q6G8X4, NADD_STAAS ;
DR   A8Z4D3, NADD_STAAT ;  P65503, NADD_STAAW ;  Q5HNV3, NADD_STAEQ ;
DR   Q8CSC1, NADD_STAES ;  Q4L6U5, NADD_STAHJ ;  Q49Y35, NADD_STAS1 ;
DR   Q9RDK7, NADD_STRCO ;  B2FPR4, NADD_STRMK ;  Q8DSI6, NADD_STRMU ;
DR   Q9A1F2, NADD_STRP1 ;  P0DC62, NADD_STRP3 ;  Q5XDT7, NADD_STRP6 ;
DR   Q8P2L2, NADD_STRP8 ;  P65504, NADD_STRPN ;  P0DC63, NADD_STRPQ ;
DR   P65505, NADD_STRR6 ;  Q30PQ2, NADD_SULDN ;  A6QCD6, NADD_SULNB ;
DR   Q67SC4, NADD_SYMTH ;  Q2LU86, NADD_SYNAS ;  Q2JWZ1, NADD_SYNJA ;
DR   Q2JNW7, NADD_SYNJB ;  P73246, NADD_SYNY3 ;  A8F479, NADD_THELT ;
DR   A6LJZ1, NADD_THEM4 ;  Q9WXV2, NADD_THEMA ;  A5IKX3, NADD_THEP1 ;
DR   B0KAB6, NADD_THEP3 ;  B0K413, NADD_THEPX ;  B9KYU7, NADD_THERP ;
DR   B1LA54, NADD_THESQ ;  Q72HR5, NADD_THET2 ;  Q5SHF0, NADD_THET8 ;
DR   Q8RBA4, NADD_THETN ;  Q31IE3, NADD_THICR ;  O83723, NADD_TREPA ;
DR   B2S3Y0, NADD_TREPS ;  Q83I10, NADD_TROW8 ;  Q83G58, NADD_TROWT ;
DR   B1H028, NADD_UNCTG ;  Q9PQ21, NADD_UREPA ;  A5CX85, NADD_VESOH ;
DR   Q8D330, NADD_WIGBR ;  B2I5T8, NADD_XYLF2 ;  Q9PBG5, NADD_XYLFA ;
DR   B0U379, NADD_XYLFM ;  Q87C62, NADD_XYLFT ;  A1JPW3, NADD_YERE8 ;
DR   A7FKW3, NADD_YERP3 ;  Q1C518, NADD_YERPA ;  B2K883, NADD_YERPB ;
DR   Q8ZDG1, NADD_YERPE ;  A9R6Z3, NADD_YERPG ;  Q1CKQ7, NADD_YERPN ;
DR   A4TP00, NADD_YERPP ;  Q66DE6, NADD_YERPS ;  B1JGA8, NADD_YERPY ;
DR   Q0VD50, NMNA1_BOVIN;  Q9HAN9, NMNA1_HUMAN;  Q9EPA7, NMNA1_MOUSE;
DR   Q0VC59, NMNA2_BOVIN;  Q6PC93, NMNA2_DANRE;  Q9BZQ4, NMNA2_HUMAN;
DR   Q8BNJ3, NMNA2_MOUSE;  Q5RBL5, NMNA2_PONAB;  Q0HA29, NMNA2_RAT  ;
DR   A4IH61, NMNA2_XENTR;  Q96T66, NMNA3_HUMAN;  Q99JR6, NMNA3_MOUSE;
//
ID   2.7.7.19
DE   Polynucleotide adenylyltransferase.
AN   NTP polymerase.
AN   Poly(A) polymerase.
AN   RNA adenylating enzyme.
CA   ATP + RNA(n) = diphosphate + RNA(n+1).
CC   -!- Also acts slowly with CTP.
CC   -!- Catalyzes template-independent extension of the 3'-end of a DNA
CC       strand by one nucleotide at a time.
CC   -!- Cannot initiate a chain de novo.
CC   -!- The primer, depending on the source of the enzyme, may be an RNA or
CC       DNA fragment or oligo(A) bearing a 3'-OH terminal group.
CC   -!- See also EC 2.7.7.6.
DR   O74326, CID11_SCHPO;  O74518, CID12_SCHPO;  Q9UT49, CID13_SCHPO;
DR   Q9UTN3, CID14_SCHPO;  Q9VD44, GLD2A_DROME;  Q641A1, GLD2A_XENLA;
DR   Q9VYS4, GLD2B_DROME;  Q6DFA8, GLD2B_XENLA;  Q2HJ44, GLD2_BOVIN ;
DR   O17087, GLD2_CAEEL ;  Q503I9, GLD2_DANRE ;  Q6PIY7, GLD2_HUMAN ;
DR   Q91YI6, GLD2_MOUSE ;  Q5U315, GLD2_RAT   ;  Q0VFA3, GLD2_XENTR ;
DR   Q65159, PAP1_ASFB7 ;  P0C9D5, PAP1_ASFK5 ;  P0C9D2, PAP1_ASFM2 ;
DR   P0C9D3, PAP1_ASFP4 ;  P0C9D4, PAP1_ASFWA ;  Q8V2W4, PAP1_CAMPM ;
DR   Q8QQ67, PAP1_CAMPS ;  Q6VZL8, PAP1_CNPV  ;  Q070J7, PAP1_CPRV  ;
DR   Q8QMZ9, PAP1_CWPXB ;  Q80E12, PAP1_CWPXG ;  Q08FW1, PAP1_DPV83 ;
DR   Q08FE1, PAP1_DPV84 ;  Q8JLG4, PAP1_ECTVM ;  Q9J5B8, PAP1_FOWPN ;
DR   Q0GP30, PAP1_HSPV  ;  Q91MX5, PAP1_LSDV  ;  Q98199, PAP1_MCV1  ;
DR   Q5UQS6, PAP1_MIMIV ;  Q9Q8R9, PAP1_MYXVL ;  Q2F8F7, PAP1_ORFN2 ;
DR   Q6RZP5, PAP1_RABPU ;  Q9Q944, PAP1_RFVKA ;  Q8V3R4, PAP1_SWPV1 ;
DR   O57184, PAP1_VACCA ;  P21079, PAP1_VACCC ;  Q9JFD9, PAP1_VACCT ;
DR   P23371, PAP1_VACCW ;  P33809, PAP1_VAR67 ;  Q9DHT0, PAP1_YLDV  ;
DR   Q6TUY0, PAP1_YMTV5 ;  Q9UW26, PAPA_CANAL ;  Q9NVV4, PAPD1_HUMAN;
DR   Q9D0D3, PAPD1_MOUSE;  P51004, PAPO1_XENLA;  P51005, PAPO2_XENLA;
DR   P51006, PAPO3_XENLA;  P25500, PAPOA_BOVIN;  P51003, PAPOA_HUMAN;
DR   Q61183, PAPOA_MOUSE;  Q9NRJ5, PAPOB_HUMAN;  Q9WVP6, PAPOB_MOUSE;
DR   Q9BWT3, PAPOG_HUMAN;  Q6PCL9, PAPOG_MOUSE;  O42617, PAP_CANAL  ;
DR   Q54J73, PAP_DICDI  ;  Q51D88, PAP_ENTHI  ;  Q10295, PAP_SCHPO  ;
DR   P29468, PAP_YEAST  ;  P0ABF3, PCNB_ECO57 ;  P0ABF2, PCNB_ECOL6 ;
DR   P0ABF1, PCNB_ECOLI ;  P44439, PCNB_HAEIN ;  Q8Z9C3, PCNB_SALTI ;
DR   Q8ZRQ8, PCNB_SALTY ;  D2HS90, STPAP_AILME;  Q1JPD6, STPAP_BOVIN;
DR   Q4KMD7, STPAP_DANRE;  Q9H6E5, STPAP_HUMAN;  Q8R3F9, STPAP_MOUSE;
DR   Q3MHT4, STPAP_RAT  ;  A9JTS5, STPAP_XENTR;
//
ID   2.7.7.20
DE   Deleted entry.
//
ID   2.7.7.21
DE   Transferred entry: 2.7.7.72.
//
ID   2.7.7.22
DE   Mannose-1-phosphate guanylyltransferase (GDP).
AN   GDP-mannose phosphorylase.
AN   GDP-mannose pyrophosphorylase.
CA   GDP + alpha-D-mannose 1-phosphate = phosphate + GDP-mannose.
//
ID   2.7.7.23
DE   UDP-N-acetylglucosamine diphosphorylase.
AN   N-acetylglucosamine-1-phosphate uridyltransferase.
AN   UDP-N-acetylglucosamine pyrophosphorylase.
CA   UTP + N-acetyl-alpha-D-glucosamine 1-phosphate = diphosphate + UDP-N-
CA   acetyl-D-glucosamine.
CC   -!- The enzyme from several bacteria has been shown to be bifunctional
CC       and also to possess the activity of EC 2.3.1.157.
PR   PROSITE; PDOC00094;
DR   B0C3K5, GLMU_ACAM1 ;  A9NH16, GLMU_ACHLI ;  A1TUE2, GLMU_ACIAC ;
DR   Q6F6U9, GLMU_ACIAD ;  B2I2B5, GLMU_ACIBC ;  Q1IQY5, GLMU_ACIBL ;
DR   B0VPT6, GLMU_ACIBS ;  B0V9X1, GLMU_ACIBY ;  A5G0T8, GLMU_ACICJ ;
DR   B9MD63, GLMU_ACIET ;  B7JB82, GLMU_ACIF2 ;  B5ER40, GLMU_ACIF5 ;
DR   A1W3Q7, GLMU_ACISJ ;  A3MZV4, GLMU_ACTP2 ;  B3H116, GLMU_ACTP7 ;
DR   B0BUE6, GLMU_ACTPJ ;  A6VLS5, GLMU_ACTSZ ;  A0KQX6, GLMU_AERHH ;
DR   B9JF80, GLMU_AGRRK ;  Q8UEH0, GLMU_AGRT5 ;  B9JWC4, GLMU_AGRVS ;
DR   Q0VKX6, GLMU_ALCBS ;  Q0A4N0, GLMU_ALHEH ;  B6EHG2, GLMU_ALISL ;
DR   A6TJM5, GLMU_ALKMQ ;  A8MK45, GLMU_ALKOO ;  B4S0Y2, GLMU_ALTMD ;
DR   B8J9N1, GLMU_ANAD2 ;  Q2IGL4, GLMU_ANADE ;  A7H7I2, GLMU_ANADF ;
DR   B9KHH2, GLMU_ANAMF ;  Q5PBV0, GLMU_ANAMM ;  B4UGJ1, GLMU_ANASK ;
DR   Q3MC88, GLMU_ANAVT ;  O66863, GLMU_AQUAE ;  A8EWU5, GLMU_ARCB4 ;
DR   Q5P5P9, GLMU_AROAE ;  A1R4G1, GLMU_ARTAT ;  B8HFD9, GLMU_ARTCA ;
DR   A8I4D4, GLMU_AZOC5 ;  A1KBP7, GLMU_AZOSB ;  C1DMJ0, GLMU_AZOVD ;
DR   A7Z0H3, GLMU_BACA2 ;  C3P9J5, GLMU_BACAA ;  C3LJ22, GLMU_BACAC ;
DR   A0R8C1, GLMU_BACAH ;  Q81VZ1, GLMU_BACAN ;  B7JK56, GLMU_BACC0 ;
DR   Q73FF9, GLMU_BACC1 ;  B7ISV9, GLMU_BACC2 ;  C1ESX9, GLMU_BACC3 ;
DR   B7HIL7, GLMU_BACC4 ;  B7HPW0, GLMU_BACC7 ;  P42817, GLMU_BACCL ;
DR   A7GJW1, GLMU_BACCN ;  B9IZD2, GLMU_BACCQ ;  Q81J98, GLMU_BACCR ;
DR   Q63HI4, GLMU_BACCZ ;  Q9KGJ6, GLMU_BACHD ;  Q6HPW8, GLMU_BACHK ;
DR   Q65PH1, GLMU_BACLD ;  P28017, GLMU_BACME ;  Q5WAD9, GLMU_BACSK ;
DR   P14192, GLMU_BACSU ;  A9VN62, GLMU_BACWK ;  A1USU8, GLMU_BARBK ;
DR   Q6G321, GLMU_BARHE ;  Q6FZH5, GLMU_BARQU ;  A9IVJ6, GLMU_BART1 ;
DR   Q1LTV6, GLMU_BAUCH ;  Q6MHV9, GLMU_BDEBA ;  B8DU78, GLMU_BIFA0 ;
DR   A1A1R9, GLMU_BIFAA ;  B3DSP5, GLMU_BIFLD ;  Q8G5P1, GLMU_BIFLO ;
DR   B7GSX2, GLMU_BIFLS ;  Q7VQV4, GLMU_BLOFL ;  Q494C1, GLMU_BLOPB ;
DR   Q2KTX5, GLMU_BORA1 ;  Q7WE21, GLMU_BORBR ;  Q7W321, GLMU_BORPA ;
DR   A9HWM1, GLMU_BORPD ;  Q7VT27, GLMU_BORPE ;  Q89LD7, GLMU_BRAJA ;
DR   A4YUF4, GLMU_BRASO ;  C0ZHD4, GLMU_BREBN ;  B2SB72, GLMU_BRUA1 ;
DR   Q2YKK2, GLMU_BRUA2 ;  Q577Y2, GLMU_BRUAB ;  A9MBM3, GLMU_BRUC2 ;
DR   C0RLA4, GLMU_BRUMB ;  Q8YC48, GLMU_BRUME ;  A9WYQ2, GLMU_BRUSI ;
DR   Q8FW78, GLMU_BRUSU ;  B8D8J0, GLMU_BUCA5 ;  P57139, GLMU_BUCAI ;
DR   Q8KA74, GLMU_BUCAP ;  B8D6U4, GLMU_BUCAT ;  Q89B26, GLMU_BUCBP ;
DR   B1YP62, GLMU_BURA4 ;  Q1BSY8, GLMU_BURCA ;  B1JZU8, GLMU_BURCC ;
DR   A0KB52, GLMU_BURCH ;  B4E935, GLMU_BURCJ ;  Q0BB89, GLMU_BURCM ;
DR   A9AKB1, GLMU_BURM1 ;  A3MND6, GLMU_BURM7 ;  Q62EP0, GLMU_BURMA ;
DR   A1V7Z3, GLMU_BURMS ;  A3NQK0, GLMU_BURP0 ;  Q3JWX1, GLMU_BURP1 ;
DR   A3N4V7, GLMU_BURP6 ;  B2JIL7, GLMU_BURP8 ;  B2T6U5, GLMU_BURPP ;
DR   Q63Y75, GLMU_BURPS ;  Q39C92, GLMU_BURS3 ;  Q2T1V2, GLMU_BURTA ;
DR   A4JIF7, GLMU_BURVG ;  Q13T65, GLMU_BURXL ;  A4XIS1, GLMU_CALS8 ;
DR   A7ZCS8, GLMU_CAMC1 ;  A7GY50, GLMU_CAMC5 ;  A0RNZ5, GLMU_CAMFF ;
DR   A7I1Y8, GLMU_CAMHC ;  A8FLN0, GLMU_CAMJ8 ;  A7H432, GLMU_CAMJD ;
DR   Q9PPA2, GLMU_CAMJE ;  A1VZG5, GLMU_CAMJJ ;  Q5HUX5, GLMU_CAMJR ;
DR   B9KCL5, GLMU_CAMLR ;  Q3AFM0, GLMU_CARHZ ;  B8GYT1, GLMU_CAUCN ;
DR   Q9A5Z3, GLMU_CAUCR ;  B3PIS4, GLMU_CELJU ;  Q1QSD2, GLMU_CHRSD ;
DR   Q7MBG1, GLMU_CHRVO ;  A8ACN3, GLMU_CITK8 ;  B0RHI9, GLMU_CLAMS ;
DR   Q97E92, GLMU_CLOAB ;  A7FPK2, GLMU_CLOB1 ;  C3KWA1, GLMU_CLOB6 ;
DR   A6LPJ1, GLMU_CLOB8 ;  B2UXS6, GLMU_CLOBA ;  B2TI07, GLMU_CLOBB ;
DR   A5I7S0, GLMU_CLOBH ;  C1FNF1, GLMU_CLOBJ ;  B1IH02, GLMU_CLOBK ;
DR   A7GJD9, GLMU_CLOBL ;  B1KTE7, GLMU_CLOBM ;  Q181B4, GLMU_CLOD6 ;
DR   B9DY47, GLMU_CLOK1 ;  A5N4I5, GLMU_CLOK5 ;  A0PXK8, GLMU_CLONN ;
DR   Q0TMG3, GLMU_CLOP1 ;  Q8XHJ3, GLMU_CLOPE ;  Q0SQ61, GLMU_CLOPS ;
DR   Q899I9, GLMU_CLOTE ;  A3DIP9, GLMU_CLOTH ;  Q47UE0, GLMU_COLP3 ;
DR   C3PF87, GLMU_CORA7 ;  Q6NI74, GLMU_CORDI ;  Q8FQV1, GLMU_COREF ;
DR   A4QCS3, GLMU_CORGB ;  Q8NRU8, GLMU_CORGL ;  Q4JU42, GLMU_CORJK ;
DR   B6J965, GLMU_COXB1 ;  B6J2E2, GLMU_COXB2 ;  A9KBF4, GLMU_COXBN ;
DR   A9NBD3, GLMU_COXBR ;  Q83AF3, GLMU_COXBU ;  Q0KF07, GLMU_CUPNH ;
DR   Q476S2, GLMU_CUPPJ ;  B2AGH8, GLMU_CUPTR ;  B8HXB5, GLMU_CYAP4 ;
DR   B7KIE0, GLMU_CYAP7 ;  B7JVE8, GLMU_CYAP8 ;  Q47JK2, GLMU_DECAR ;
DR   Q1IWX3, GLMU_DEIGD ;  Q9RW61, GLMU_DEIRA ;  B1I194, GLMU_DESAP ;
DR   Q313W4, GLMU_DESDG ;  B8FY55, GLMU_DESHD ;  Q251V1, GLMU_DESHY ;
DR   Q6AMF9, GLMU_DESPS ;  A4J0P6, GLMU_DESRM ;  Q728D5, GLMU_DESVH ;
DR   B8DKH2, GLMU_DESVM ;  A1VAZ5, GLMU_DESVV ;  A5EXL2, GLMU_DICNV ;
DR   A8LIS2, GLMU_DINSH ;  A7ZTU1, GLMU_ECO24 ;  B7UMJ5, GLMU_ECO27 ;
DR   B7MGF0, GLMU_ECO45 ;  B7L878, GLMU_ECO55 ;  P0ACC8, GLMU_ECO57 ;
DR   B5YXD4, GLMU_ECO5E ;  B7NR32, GLMU_ECO7I ;  B7N2G9, GLMU_ECO81 ;
DR   B7M586, GLMU_ECO8A ;  C4ZZ08, GLMU_ECOBW ;  B1X9V8, GLMU_ECODH ;
DR   A8A6J2, GLMU_ECOHS ;  A1AHR2, GLMU_ECOK1 ;  Q0TAX9, GLMU_ECOL5 ;
DR   Q8FBT3, GLMU_ECOL6 ;  B1IX08, GLMU_ECOLC ;  P0ACC7, GLMU_ECOLI ;
DR   B7NF46, GLMU_ECOLU ;  B6I3W7, GLMU_ECOSE ;  B1LL57, GLMU_ECOSM ;
DR   Q1R4K5, GLMU_ECOUT ;  C5BF42, GLMU_EDWI9 ;  A4WGF8, GLMU_ENT38 ;
DR   Q839U1, GLMU_ENTFA ;  A7MMY0, GLMU_ENTS8 ;  Q6CYJ8, GLMU_ERWCT ;
DR   B2VCC9, GLMU_ERWT9 ;  B7LK74, GLMU_ESCF3 ;  B1YGP5, GLMU_EXIS2 ;
DR   C4KZV1, GLMU_EXISA ;  A7HKM7, GLMU_FERNB ;  B0TZM4, GLMU_FRAP2 ;
DR   Q2J5Y1, GLMU_FRASC ;  Q14J62, GLMU_FRAT1 ;  A7NAF3, GLMU_FRATF ;
DR   Q2A4X7, GLMU_FRATH ;  B2SFB5, GLMU_FRATM ;  A0Q565, GLMU_FRATN ;
DR   Q0BN96, GLMU_FRATO ;  Q5NHR0, GLMU_FRATT ;  A4IZM7, GLMU_FRATW ;
DR   Q8RHM3, GLMU_FUSNN ;  Q5L3V0, GLMU_GEOKA ;  B3E414, GLMU_GEOLS ;
DR   Q39ZH2, GLMU_GEOMG ;  B9M701, GLMU_GEOSF ;  Q74GH5, GLMU_GEOSL ;
DR   C5D371, GLMU_GEOSW ;  A4IJC6, GLMU_GEOTN ;  A5GDL4, GLMU_GEOUR ;
DR   Q7NNG8, GLMU_GLOVI ;  A9HI46, GLMU_GLUDA ;  Q5FUY6, GLMU_GLUOX ;
DR   Q0BSR5, GLMU_GRABC ;  Q7VLE6, GLMU_HAEDU ;  Q4QMS5, GLMU_HAEI8 ;
DR   A5UE94, GLMU_HAEIE ;  A5UHD3, GLMU_HAEIG ;  P43889, GLMU_HAEIN ;
DR   B8F3K4, GLMU_HAEPS ;  Q0I1G0, GLMU_HAES1 ;  B0UW09, GLMU_HAES2 ;
DR   Q2S6P3, GLMU_HAHCH ;  A1WZS9, GLMU_HALHL ;  C4K351, GLMU_HAMD5 ;
DR   Q17XI1, GLMU_HELAH ;  Q7VIB6, GLMU_HELHP ;  B0TBA0, GLMU_HELMI ;
DR   B6JLS1, GLMU_HELP2 ;  Q1CTI8, GLMU_HELPH ;  Q9ZLF6, GLMU_HELPJ ;
DR   O25393, GLMU_HELPY ;  A4G9W6, GLMU_HERAR ;  B4U648, GLMU_HYDS0 ;
DR   Q0C4B0, GLMU_HYPNA ;  Q5QZH4, GLMU_IDILO ;  A6T3N4, GLMU_JANMA ;
DR   Q28MG0, GLMU_JANSC ;  A6W6V0, GLMU_KINRD ;  B5XZM7, GLMU_KLEP3 ;
DR   A6TG34, GLMU_KLEP7 ;  C5CFS2, GLMU_KOSOT ;  Q5FMG0, GLMU_LACAC ;
DR   Q03T39, GLMU_LACBA ;  Q1GBQ8, GLMU_LACDA ;  Q04C57, GLMU_LACDB ;
DR   B2GFE2, GLMU_LACF3 ;  Q046K2, GLMU_LACGA ;  A8YX58, GLMU_LACH4 ;
DR   Q74LH7, GLMU_LACJO ;  Q9CEF8, GLMU_LACLA ;  A2RMV7, GLMU_LACLM ;
DR   Q02WW6, GLMU_LACLS ;  Q88Z86, GLMU_LACPL ;  A5VI16, GLMU_LACRD ;
DR   B2G5J5, GLMU_LACRJ ;  Q1WV55, GLMU_LACS1 ;  Q38V29, GLMU_LACSS ;
DR   Q1MQ72, GLMU_LAWIP ;  Q5X112, GLMU_LEGPA ;  A5II48, GLMU_LEGPC ;
DR   Q5ZRK6, GLMU_LEGPH ;  Q5WST8, GLMU_LEGPL ;  Q6ADP6, GLMU_LEIXX ;
DR   Q92F69, GLMU_LISIN ;  C1KYD1, GLMU_LISMC ;  Q724L5, GLMU_LISMF ;
DR   B8DGM7, GLMU_LISMH ;  Q8YAD4, GLMU_LISMO ;  A0AF03, GLMU_LISW6 ;
DR   Q2W7U1, GLMU_MAGSA ;  Q65R54, GLMU_MANSM ;  A1U7H2, GLMU_MARAV ;
DR   Q0AR24, GLMU_MARMM ;  A6VTC6, GLMU_MARMS ;  Q11HG1, GLMU_MESSB ;
DR   A6UUQ4, GLMU_META3 ;  Q60CR2, GLMU_METCA ;  Q1GXN2, GLMU_METFK ;
DR   Q58501, GLMU_METJA ;  A4FX98, GLMU_METM5 ;  A6VG23, GLMU_METM7 ;
DR   Q6LYB5, GLMU_METMP ;  A2SD80, GLMU_METPP ;  A6UP85, GLMU_METVS ;
DR   B0JJ82, GLMU_MICAN ;  C5C9D1, GLMU_MICLC ;  Q2RMC5, GLMU_MOOTA ;
DR   A0QBW9, GLMU_MYCA1 ;  Q7VF00, GLMU_MYCBO ;  A1KHF6, GLMU_MYCBP ;
DR   C1AM09, GLMU_MYCBT ;  A4T6M7, GLMU_MYCGI ;  B8ZU67, GLMU_MYCLB ;
DR   Q9CD44, GLMU_MYCLE ;  B2HDJ0, GLMU_MYCMM ;  Q741V3, GLMU_MYCPA ;
DR   A0R3C7, GLMU_MYCS2 ;  A3Q5G5, GLMU_MYCSJ ;  A1UL17, GLMU_MYCSK ;
DR   Q1B431, GLMU_MYCSS ;  A5U161, GLMU_MYCTA ;  P96382, GLMU_MYCTU ;
DR   A0PW60, GLMU_MYCUA ;  A1TEF5, GLMU_MYCVP ;  Q1DCI1, GLMU_MYXXD ;
DR   B9LAA1, GLMU_NAUPA ;  Q5F577, GLMU_NEIG1 ;  Q50986, GLMU_NEIGO ;
DR   A9LZT7, GLMU_NEIM0 ;  Q9JWN3, GLMU_NEIMA ;  Q9K1P3, GLMU_NEIMB ;
DR   A1KR65, GLMU_NEIMF ;  Q0AJA8, GLMU_NITEC ;  Q82XP7, GLMU_NITEU ;
DR   Q1QME9, GLMU_NITHX ;  Q2YCA1, GLMU_NITMU ;  Q3J6N3, GLMU_NITOC ;
DR   A6Q403, GLMU_NITSB ;  Q3SRP6, GLMU_NITWN ;  Q5YQ11, GLMU_NOCFA ;
DR   B2IU73, GLMU_NOSP7 ;  Q8YQB2, GLMU_NOSS1 ;  Q2G929, GLMU_NOVAD ;
DR   Q8CXP9, GLMU_OCEIH ;  A6X546, GLMU_OCHA4 ;  Q04DS4, GLMU_OENOB ;
DR   B6JFB2, GLMU_OLICO ;  A1AZN6, GLMU_PARDP ;  A7HXP0, GLMU_PARL1 ;
DR   Q9CK29, GLMU_PASMU ;  C6DJH5, GLMU_PECCP ;  Q03HD2, GLMU_PEDPA ;
DR   Q3A0D8, GLMU_PELCD ;  A1ALB2, GLMU_PELPD ;  A5D662, GLMU_PELTS ;
DR   Q7NA96, GLMU_PHOLL ;  Q6LLH1, GLMU_PHOPR ;  A1VJM6, GLMU_POLNA ;
DR   Q12FR3, GLMU_POLSJ ;  Q6AAD3, GLMU_PROAC ;  A3PBY5, GLMU_PROM0 ;
DR   A8G3X7, GLMU_PROM2 ;  A9BAV8, GLMU_PROM4 ;  A2BVS4, GLMU_PROM5 ;
DR   Q31BS3, GLMU_PROM9 ;  Q7VBP2, GLMU_PROMA ;  B4F0E9, GLMU_PROMH ;
DR   Q7V8F2, GLMU_PROMM ;  Q7V274, GLMU_PROMP ;  A2BQ92, GLMU_PROMS ;
DR   Q46LT9, GLMU_PROMT ;  Q48BG7, GLMU_PSE14 ;  Q15P09, GLMU_PSEA6 ;
DR   A6VF30, GLMU_PSEA7 ;  B7V789, GLMU_PSEA8 ;  Q02DF6, GLMU_PSEAB ;
DR   Q9HT22, GLMU_PSEAE ;  Q1I2I9, GLMU_PSEE4 ;  Q4K3B1, GLMU_PSEF5 ;
DR   C3K1E4, GLMU_PSEFS ;  Q3IK30, GLMU_PSEHT ;  A4Y185, GLMU_PSEMY ;
DR   A5WBA1, GLMU_PSEP1 ;  Q3K443, GLMU_PSEPF ;  B0KRA6, GLMU_PSEPG ;
DR   Q88BX6, GLMU_PSEPK ;  Q87TT6, GLMU_PSESM ;  Q4ZL26, GLMU_PSEU2 ;
DR   A4VS60, GLMU_PSEU5 ;  Q4FPY8, GLMU_PSYA2 ;  Q1Q830, GLMU_PSYCK ;
DR   A1SZH6, GLMU_PSYIN ;  A5WHT0, GLMU_PSYWF ;  Q1LS04, GLMU_RALME ;
DR   B2UD47, GLMU_RALPJ ;  Q8Y304, GLMU_RALSO ;  B3PZN3, GLMU_RHIE6 ;
DR   Q2K8G2, GLMU_RHIEC ;  Q1MGP8, GLMU_RHIL3 ;  Q98LX2, GLMU_RHILO ;
DR   B5ZP51, GLMU_RHILW ;  Q92PS3, GLMU_RHIME ;  C3MCF7, GLMU_RHISN ;
DR   Q21ZH9, GLMU_RHOFD ;  C1AY41, GLMU_RHOOB ;  Q2IW53, GLMU_RHOP2 ;
DR   Q07MW2, GLMU_RHOP5 ;  Q6N6F8, GLMU_RHOPA ;  Q214N1, GLMU_RHOPB ;
DR   Q136Z3, GLMU_RHOPS ;  B3QIT8, GLMU_RHOPT ;  Q2RPX0, GLMU_RHORT ;
DR   Q3J3H0, GLMU_RHOS4 ;  A4WU43, GLMU_RHOS5 ;  Q0S4N3, GLMU_RHOSR ;
DR   Q163N8, GLMU_ROSDO ;  Q1AXL7, GLMU_RUBXD ;  A1AXS8, GLMU_RUTMC ;
DR   Q21DL5, GLMU_SACD2 ;  B5EYZ3, GLMU_SALA4 ;  A9MJS2, GLMU_SALAR ;
DR   Q57HY1, GLMU_SALCH ;  B5FN29, GLMU_SALDC ;  B5QUS1, GLMU_SALEP ;
DR   B5RFW6, GLMU_SALG2 ;  B4TAW9, GLMU_SALHS ;  B4SYC8, GLMU_SALNS ;
DR   Q5PKV8, GLMU_SALPA ;  A9MXA3, GLMU_SALPB ;  B5BIN3, GLMU_SALPK ;
DR   B4TN27, GLMU_SALSV ;  Q8Z2Q3, GLMU_SALTI ;  Q8ZKX0, GLMU_SALTY ;
DR   A8G7N0, GLMU_SERP5 ;  A1SBT8, GLMU_SHEAM ;  B8EDU8, GLMU_SHEB2 ;
DR   A3DAR2, GLMU_SHEB5 ;  A6WUI8, GLMU_SHEB8 ;  A9KX04, GLMU_SHEB9 ;
DR   Q12HQ5, GLMU_SHEDO ;  Q07VU6, GLMU_SHEFN ;  B0TQE8, GLMU_SHEHH ;
DR   A3QJQ7, GLMU_SHELP ;  Q8E8C2, GLMU_SHEON ;  A8HAG0, GLMU_SHEPA ;
DR   A4YCH6, GLMU_SHEPC ;  B8CVU0, GLMU_SHEPW ;  A0L2S6, GLMU_SHESA ;
DR   A8G1W3, GLMU_SHESH ;  Q0HD81, GLMU_SHESM ;  Q0HPG3, GLMU_SHESR ;
DR   A1RQA8, GLMU_SHESW ;  B1KQ31, GLMU_SHEWM ;  B2TUP5, GLMU_SHIB3 ;
DR   Q31UN0, GLMU_SHIBS ;  Q329R9, GLMU_SHIDS ;  Q0SYU6, GLMU_SHIF8 ;
DR   Q83IY3, GLMU_SHIFL ;  Q3YVN4, GLMU_SHISS ;  Q5LPQ1, GLMU_SILPO ;
DR   Q1GIQ5, GLMU_SILST ;  A6U9C1, GLMU_SINMW ;  Q2NQ84, GLMU_SODGM ;
DR   Q01YD9, GLMU_SOLUE ;  A9FSV7, GLMU_SORC5 ;  Q1GTD8, GLMU_SPHAL ;
DR   A5VF26, GLMU_SPHWW ;  Q2FJE2, GLMU_STAA3 ;  Q2G0S3, GLMU_STAA8 ;
DR   Q2YVU6, GLMU_STAAB ;  Q5HIH6, GLMU_STAAC ;  Q99WA4, GLMU_STAAM ;
DR   Q7A7B4, GLMU_STAAN ;  Q6GJH2, GLMU_STAAR ;  Q6GBY9, GLMU_STAAS ;
DR   Q8NXZ7, GLMU_STAAW ;  B9DLD6, GLMU_STACT ;  Q937Z1, GLMU_STAEP ;
DR   Q5HRQ6, GLMU_STAEQ ;  Q8CMT0, GLMU_STAES ;  Q4L3F6, GLMU_STAHJ ;
DR   Q49V08, GLMU_STAS1 ;  Q3JZY6, GLMU_STRA1 ;  Q8E409, GLMU_STRA3 ;
DR   Q8DYE6, GLMU_STRA5 ;  Q82HE8, GLMU_STRAW ;  Q8CJX6, GLMU_STRCO ;
DR   A8AY88, GLMU_STRGC ;  B1VUI7, GLMU_STRGG ;  B4SJR6, GLMU_STRM5 ;
DR   B2FHY5, GLMU_STRMK ;  Q8DSX2, GLMU_STRMU ;  Q9A163, GLMU_STRP1 ;
DR   Q04KU2, GLMU_STRP2 ;  P0DB62, GLMU_STRP3 ;  B5E4A8, GLMU_STRP4 ;
DR   Q5XDJ2, GLMU_STRP6 ;  C1C6W6, GLMU_STRP7 ;  Q8P286, GLMU_STRP8 ;
DR   Q1JD75, GLMU_STRPB ;  Q1JN46, GLMU_STRPC ;  Q1J847, GLMU_STRPF ;
DR   A2RG45, GLMU_STRPG ;  B1IBE8, GLMU_STRPI ;  Q48UZ1, GLMU_STRPM ;
DR   Q97R46, GLMU_STRPN ;  P0DB63, GLMU_STRPQ ;  B5XK49, GLMU_STRPZ ;
DR   Q8DQ18, GLMU_STRR6 ;  A4W313, GLMU_STRS2 ;  A3CPC4, GLMU_STRSV ;
DR   A4VWR1, GLMU_STRSY ;  Q8GQP7, GLMU_STRSZ ;  Q5M0U2, GLMU_STRT1 ;
DR   Q5M5C8, GLMU_STRT2 ;  Q03LQ1, GLMU_STRTD ;  B9DRD5, GLMU_STRU0 ;
DR   C1CDY3, GLMU_STRZJ ;  C1CRR4, GLMU_STRZT ;  Q30RT9, GLMU_SULDN ;
DR   A6QBC4, GLMU_SULNB ;  Q67JC8, GLMU_SYMTH ;  Q31RJ9, GLMU_SYNE7 ;
DR   Q2JVA4, GLMU_SYNJA ;  Q2JII9, GLMU_SYNJB ;  B1XLT6, GLMU_SYNP2 ;
DR   Q5N2Q6, GLMU_SYNP6 ;  Q7U7I0, GLMU_SYNPX ;  A5GT42, GLMU_SYNR3 ;
DR   Q0I9Y4, GLMU_SYNS3 ;  Q3AVF3, GLMU_SYNS9 ;  Q3AKJ8, GLMU_SYNSC ;
DR   Q0B0S9, GLMU_SYNWW ;  Q55504, GLMU_SYNY3 ;  B7IFM4, GLMU_THEAB ;
DR   Q8DLT5, GLMU_THEEB ;  Q47SW5, GLMU_THEFY ;  A8F4D4, GLMU_THELT ;
DR   A6LJD6, GLMU_THEM4 ;  Q9X1W4, GLMU_THEMA ;  A5ILV3, GLMU_THEP1 ;
DR   B0KBF5, GLMU_THEP3 ;  B1LBD9, GLMU_THESQ ;  Q72LP1, GLMU_THET2 ;
DR   Q5SLA8, GLMU_THET8 ;  Q8R752, GLMU_THETN ;  B5YHS4, GLMU_THEYD ;
DR   Q31DM2, GLMU_THICR ;  Q3SF69, GLMU_THIDA ;  B8GRB6, GLMU_THISH ;
DR   C4L8R0, GLMU_TOLAT ;  Q118R6, GLMU_TRIEI ;  Q83NE5, GLMU_TROW8 ;
DR   Q83GR0, GLMU_TROWT ;  A5CVK9, GLMU_VESOH ;  A5F461, GLMU_VIBC3 ;
DR   Q9KNH7, GLMU_VIBCH ;  C3LSI7, GLMU_VIBCM ;  Q5E1N9, GLMU_VIBF1 ;
DR   B5FCY9, GLMU_VIBFM ;  A7N0Z7, GLMU_VIBHB ;  Q87KB0, GLMU_VIBPA ;
DR   Q8DDG6, GLMU_VIBVU ;  Q7MGI2, GLMU_VIBVY ;  Q8D3J1, GLMU_WIGBR ;
DR   Q73IM4, GLMU_WOLPM ;  Q7M7T9, GLMU_WOLSU ;  Q5GTJ4, GLMU_WOLTR ;
DR   Q8PGH2, GLMU_XANAC ;  Q3BP20, GLMU_XANC5 ;  Q4UQF8, GLMU_XANC8 ;
DR   B0RWB8, GLMU_XANCB ;  Q8PCZ1, GLMU_XANCP ;  Q2P7P9, GLMU_XANOM ;
DR   Q5H4Y0, GLMU_XANOR ;  A7INP6, GLMU_XANP2 ;  B2I874, GLMU_XYLF2 ;
DR   Q9PE88, GLMU_XYLFA ;  B0U595, GLMU_XYLFM ;  Q87E93, GLMU_XYLFT ;
DR   A1JTC3, GLMU_YERE8 ;  A7FPD8, GLMU_YERP3 ;  Q1C097, GLMU_YERPA ;
DR   B2K849, GLMU_YERPB ;  Q8Z9S7, GLMU_YERPE ;  Q1CCH7, GLMU_YERPN ;
DR   A4TSJ5, GLMU_YERPP ;  Q663R0, GLMU_YERPS ;  B1JRN4, GLMU_YERPY ;
DR   Q5NQ83, GLMU_ZYMMO ;  O64765, UAP1_ARATH ;  Q18493, UAP1_CAEEL ;
DR   O74933, UAP1_CANAL ;  Q54GN5, UAP1_DICDI ;  Q8SQS1, UAP1_ENCCU ;
DR   Q16222, UAP1_HUMAN ;  Q91YN5, UAP1_MOUSE ;  O94617, UAP1_SCHPO ;
DR   P43123, UAP1_YEAST ;  Q5UNV4, UNAP_MIMIV ;
//
ID   2.7.7.24
DE   Glucose-1-phosphate thymidylyltransferase.
AN   dTDP-glucose diphosphorylase.
AN   dTDP-glucose pyrophosphorylase.
AN   dTDP-glucose synthase.
CA   dTTP + alpha-D-glucose 1-phosphate = diphosphate + dTDP-glucose.
DR   P37744, RMLA1_ECOLI;  P37779, RMLA1_SHIFL;  P61887, RMLA2_ECOLI;
DR   P61888, RMLA2_SHIFL;  P55253, RMLA3_ECOLX;  Q9ZAE7, RMLA_ACTS5 ;
DR   A0QPF9, RMLA_MYCS2 ;  P72017, RMLA_MYCTU ;  P37762, RMLA_NEIGO ;
DR   P57040, RMLA_NEIMA ;  P55255, RMLA_NEIMB ;  P55464, RMLA_RHISN ;
DR   P55254, RMLA_SALAN ;  P26393, RMLA_SALTY ;  P08075, RMLA_STRGR ;
DR   P95778, RMLA_STRMU ;  B0RVK9, RMLA_XANCB ;  P0C7J4, RMLA_XANCP ;
DR   P55257, RMLA_YEREN ;  P29785, STRO_STRGR ;
//
ID   2.7.7.25
DE   Transferred entry: 2.7.7.72.
//
ID   2.7.7.26
DE   Transferred entry: 3.1.27.3.
//
ID   2.7.7.27
DE   Glucose-1-phosphate adenylyltransferase.
AN   ADP-glucose diphosphorylase.
AN   ADP-glucose pyrophosphorylase.
AN   ADP-glucose synthase.
CA   ATP + alpha-D-glucose 1-phosphate = diphosphate + ADP-glucose.
PR   PROSITE; PDOC00638;
DR   Q0AAX8, GLGC1_ALHEH;  Q15U36, GLGC1_PSEA6;  Q9KRB5, GLGC1_VIBCH;
DR   Q87QX6, GLGC1_VIBPA;  Q8DAR1, GLGC1_VIBVU;  Q7MJ49, GLGC1_VIBVY;
DR   Q0AA25, GLGC2_ALHEH;  Q15RP8, GLGC2_PSEA6;  Q9KLP4, GLGC2_VIBCH;
DR   Q87HX3, GLGC2_VIBPA;  Q8D7E0, GLGC2_VIBVU;  Q7MEE9, GLGC2_VIBVY;
DR   A1TRG1, GLGC_ACIAC ;  Q1ISX7, GLGC_ACIBL ;  A0LVY3, GLGC_ACIC1 ;
DR   A6VP17, GLGC_ACTSZ ;  B9JAA3, GLGC_AGRRK ;  Q8U8L5, GLGC_AGRT5 ;
DR   B4RS18, GLGC_ALTMD ;  B8J7Y5, GLGC_ANAD2 ;  Q2IM42, GLGC_ANADE ;
DR   A7H6H5, GLGC_ANADF ;  B4ULA3, GLGC_ANASK ;  Q3MBJ4, GLGC_ANAVT ;
DR   Q5NXZ4, GLGC_AROAE ;  A1R6L8, GLGC_ARTAT ;  B8H8I4, GLGC_ARTCA ;
DR   A0JWV0, GLGC_ARTS2 ;  A1K6F9, GLGC_AZOSB ;  A0RK86, GLGC_BACAH ;
DR   Q81K83, GLGC_BACAN ;  Q72YJ4, GLGC_BACC1 ;  P30522, GLGC_BACCL ;
DR   A7GUA0, GLGC_BACCN ;  B9J2G7, GLGC_BACCQ ;  Q816G7, GLGC_BACCR ;
DR   Q632H2, GLGC_BACCZ ;  Q9KDX4, GLGC_BACHD ;  Q6HC16, GLGC_BACHK ;
DR   Q65FS5, GLGC_BACLD ;  P39122, GLGC_BACSU ;  A9VM89, GLGC_BACWK ;
DR   B8DUN4, GLGC_BIFA0 ;  A1A1B4, GLGC_BIFAA ;  B3DSC7, GLGC_BIFLD ;
DR   Q8G5Y5, GLGC_BIFLO ;  B7GS87, GLGC_BIFLS ;  Q89G87, GLGC_BRAJA ;
DR   B2JCH8, GLGC_BURP8 ;  B2T2Z5, GLGC_BURPP ;  Q141E6, GLGC_BURXL ;
DR   Q97GX8, GLGC_CLOAB ;  A6M331, GLGC_CLOB8 ;  B2V046, GLGC_CLOBA ;
DR   B2TR25, GLGC_CLOBB ;  Q9L385, GLGC_CLOCE ;  Q18A75, GLGC_CLOD6 ;
DR   A5N2Y9, GLGC_CLOK5 ;  A0Q3I7, GLGC_CLONN ;  Q8XP97, GLGC_CLOPE ;
DR   Q0SWS5, GLGC_CLOPS ;  A3DK82, GLGC_CLOTH ;  C3PFJ1, GLGC_CORA7 ;
DR   Q6NHY8, GLGC_CORDI ;  Q8FQE4, GLGC_COREF ;  A4QD83, GLGC_CORGB ;
DR   Q8NRD4, GLGC_CORGL ;  Q4JUF1, GLGC_CORJK ;  C4LHU9, GLGC_CORK4 ;
DR   B1WT08, GLGC_CYAA5 ;  B8HM61, GLGC_CYAP4 ;  B7KDB8, GLGC_CYAP7 ;
DR   B7K5U7, GLGC_CYAP8 ;  Q47II9, GLGC_DECAR ;  C1CV18, GLGC_DEIDV ;
DR   Q1J021, GLGC_DEIGD ;  Q9RTR7, GLGC_DEIRA ;  B8G1G5, GLGC_DESHD ;
DR   Q24VW5, GLGC_DESHY ;  A4J4I2, GLGC_DESRM ;  A7ZSW3, GLGC_ECO24 ;
DR   B7UKY7, GLGC_ECO27 ;  B7MDR5, GLGC_ECO45 ;  B7L4W0, GLGC_ECO55 ;
DR   P0A6V3, GLGC_ECO57 ;  B5YUI6, GLGC_ECO5E ;  B7NMJ5, GLGC_ECO7I ;
DR   B7N1M2, GLGC_ECO81 ;  B7M2J3, GLGC_ECO8A ;  C4ZVY0, GLGC_ECOBW ;
DR   B1X775, GLGC_ECODH ;  A8A5P0, GLGC_ECOHS ;  Q0TC29, GLGC_ECOL5 ;
DR   P0A6V2, GLGC_ECOL6 ;  B1IP34, GLGC_ECOLC ;  P0A6V1, GLGC_ECOLI ;
DR   B7NE40, GLGC_ECOLU ;  B6I2Z6, GLGC_ECOSE ;  B1LI91, GLGC_ECOSM ;
DR   Q1R5J6, GLGC_ECOUT ;  A4WFL3, GLGC_ENT38 ;  A7MGF4, GLGC_ENTS8 ;
DR   Q6CZK2, GLGC_ERWCT ;  B7LSE1, GLGC_ESCF3 ;  C4Z4L8, GLGC_EUBE2 ;
DR   B1YK68, GLGC_EXIS2 ;  A7HN65, GLGC_FERNB ;  Q0RH38, GLGC_FRAAA ;
DR   B0TZI3, GLGC_FRAP2 ;  Q2JCE9, GLGC_FRASC ;  A8KYU3, GLGC_FRASN ;
DR   A7NAI4, GLGC_FRATF ;  Q2A4U5, GLGC_FRATH ;  B2SFM9, GLGC_FRATM ;
DR   A0Q595, GLGC_FRATN ;  Q0BN65, GLGC_FRATO ;  A4IZK0, GLGC_FRATW ;
DR   Q8RF63, GLGC_FUSNN ;  C1ACL9, GLGC_GEMAT ;  B3E8Z1, GLGC_GEOLS ;
DR   Q39RY8, GLGC_GEOMG ;  O08326, GLGC_GEOSE ;  A4IS22, GLGC_GEOTN ;
DR   Q0BPL4, GLGC_GRABC ;  Q4QK69, GLGC_HAEI8 ;  P43796, GLGC_HAEIN ;
DR   Q0I3H9, GLGC_HAES1 ;  B0UU87, GLGC_HAES2 ;  Q28MN1, GLGC_JANSC ;
DR   B5XTQ9, GLGC_KLEP3 ;  A6TF49, GLGC_KLEP7 ;  B2GHR6, GLGC_KOCRD ;
DR   Q5FL67, GLGC_LACAC ;  Q036S8, GLGC_LACC3 ;  B3W9A3, GLGC_LACCB ;
DR   Q9CHN1, GLGC_LACLA ;  A2RMB7, GLGC_LACLM ;  Q030T6, GLGC_LACLS ;
DR   Q890J0, GLGC_LACPL ;  Q1WSM9, GLGC_LACS1 ;  Q6AF21, GLGC_LEIXX ;
DR   Q2W5G1, GLGC_MAGSA ;  Q65TI2, GLGC_MANSM ;  Q608L6, GLGC_METCA ;
DR   Q1H1K1, GLGC_METFK ;  B1MLL3, GLGC_MYCA9 ;  P64242, GLGC_MYCBO ;
DR   A1KI01, GLGC_MYCBP ;  C1AMK7, GLGC_MYCBT ;  A4T8X4, GLGC_MYCGI ;
DR   B8ZQY9, GLGC_MYCLB ;  Q9CCA8, GLGC_MYCLE ;  B2HS55, GLGC_MYCMM ;
DR   Q6KHP5, GLGC_MYCMO ;  Q73WU6, GLGC_MYCPA ;  Q1B4S9, GLGC_MYCSS ;
DR   A5U1R1, GLGC_MYCTA ;  P64241, GLGC_MYCTU ;  A0PVW7, GLGC_MYCUA ;
DR   A1TDM8, GLGC_MYCVP ;  Q1DC47, GLGC_MYXXD ;  Q82T88, GLGC_NITEU ;
DR   Q2YB46, GLGC_NITMU ;  Q3JCM9, GLGC_NITOC ;  Q5YQG3, GLGC_NOCFA ;
DR   B2IUY3, GLGC_NOSP7 ;  P30521, GLGC_NOSS1 ;  Q2G7S6, GLGC_NOVAD ;
DR   Q8ET56, GLGC_OCEIH ;  Q9CN92, GLGC_PASMU ;  C6DH77, GLGC_PECCP ;
DR   Q6LKA2, GLGC_PHOPR ;  Q6AA20, GLGC_PROAC ;  B3Q000, GLGC_RHIE6 ;
DR   Q2K486, GLGC_RHIEC ;  Q1MBS8, GLGC_RHIL3 ;  Q985P3, GLGC_RHILO ;
DR   B5ZQ46, GLGC_RHILW ;  Q92M13, GLGC_RHIME ;  P39669, GLGC_RHIRD ;
DR   C3MIS7, GLGC_RHISN ;  Q9EUT6, GLGC_RHITR ;  Q7UXF5, GLGC_RHOBA ;
DR   C1A2N3, GLGC_RHOE4 ;  Q221N8, GLGC_RHOFD ;  C1AZL1, GLGC_RHOOB ;
DR   Q2J307, GLGC_RHOP2 ;  Q07TH7, GLGC_RHOP5 ;  Q6NCT8, GLGC_RHOPA ;
DR   Q21BQ2, GLGC_RHOPB ;  Q13EA6, GLGC_RHOPS ;  B3Q9C1, GLGC_RHOPT ;
DR   Q2RS49, GLGC_RHORT ;  Q9ZFN4, GLGC_RHORU ;  A3PJX6, GLGC_RHOS1 ;
DR   Q9RNH7, GLGC_RHOS4 ;  A4WRM1, GLGC_RHOS5 ;  Q0S3Y4, GLGC_RHOSR ;
DR   Q165E3, GLGC_ROSDO ;  Q21M27, GLGC_SACD2 ;  B5F8Q2, GLGC_SALA4 ;
DR   A9MMA2, GLGC_SALAR ;  Q57IU0, GLGC_SALCH ;  B5FKF5, GLGC_SALDC ;
DR   B5R395, GLGC_SALEP ;  B4T868, GLGC_SALHS ;  B4SVN3, GLGC_SALNS ;
DR   Q5PM08, GLGC_SALPA ;  A9MTV2, GLGC_SALPB ;  C0Q0L0, GLGC_SALPC ;
DR   B5BHI0, GLGC_SALPK ;  B4TY87, GLGC_SALSV ;  Q8Z233, GLGC_SALTI ;
DR   P05415, GLGC_SALTY ;  A8GKU8, GLGC_SERP5 ;  A1S8E8, GLGC_SHEAM ;
DR   B8EAW7, GLGC_SHEB2 ;  A3D289, GLGC_SHEB5 ;  A6WKY5, GLGC_SHEB8 ;
DR   A9KTJ4, GLGC_SHEB9 ;  Q081Q7, GLGC_SHEFN ;  Q8EGU3, GLGC_SHEON ;
DR   A4Y4U6, GLGC_SHEPC ;  A0KZD8, GLGC_SHESA ;  Q0HGJ1, GLGC_SHESM ;
DR   Q0HST8, GLGC_SHESR ;  A1RLX5, GLGC_SHESW ;  B2U4G2, GLGC_SHIB3 ;
DR   Q31VJ3, GLGC_SHIBS ;  Q32AV5, GLGC_SHIDS ;  Q0SZN4, GLGC_SHIF8 ;
DR   P0A6V4, GLGC_SHIFL ;  Q3YW95, GLGC_SHISS ;  Q3K1K4, GLGC_STRA1 ;
DR   Q8E5V7, GLGC_STRA3 ;  Q8E080, GLGC_STRA5 ;  Q826D9, GLGC_STRAW ;
DR   P72394, GLGC_STRCO ;  A8AYH2, GLGC_STRGC ;  Q8DT53, GLGC_STRMU ;
DR   Q04KG7, GLGC_STRP2 ;  B5E4N4, GLGC_STRP4 ;  C1C7B5, GLGC_STRP7 ;
DR   B1IBQ8, GLGC_STRPI ;  B8ZPW3, GLGC_STRPJ ;  Q97QS7, GLGC_STRPN ;
DR   B2IPY6, GLGC_STRPS ;  Q8DPS5, GLGC_STRR6 ;  C0MH79, GLGC_STRS7 ;
DR   A3CM02, GLGC_STRSV ;  B9DRS6, GLGC_STRU0 ;  C1CEA8, GLGC_STRZJ ;
DR   C1CKI5, GLGC_STRZP ;  C1CRM1, GLGC_STRZT ;  Q31QN4, GLGC_SYNE7 ;
DR   B1XLF1, GLGC_SYNP2 ;  Q5N3K9, GLGC_SYNP6 ;  A5GLA9, GLGC_SYNPW ;
DR   P52415, GLGC_SYNY3 ;  C5BQ92, GLGC_TERTT ;  B7IFV2, GLGC_THEAB ;
DR   O52049, GLGC_THECA ;  A8F3W8, GLGC_THELT ;  A6LJL4, GLGC_THEM4 ;
DR   Q9WY82, GLGC_THEMA ;  B9K6N9, GLGC_THENN ;  A5IKI1, GLGC_THEP1 ;
DR   B9L1J9, GLGC_THERP ;  B1L9R3, GLGC_THESQ ;  Q72G72, GLGC_THET2 ;
DR   Q5SMC1, GLGC_THET8 ;  B5YIR0, GLGC_THEYD ;  Q31IB9, GLGC_THICR ;
DR   Q3SH75, GLGC_THIDA ;  Q5DZC0, GLGC_VIBF1 ;  B5EUW3, GLGC_VIBFM ;
DR   A7FNX3, GLGC_YERP3 ;  Q1C1E1, GLGC_YERPA ;  B2K6F9, GLGC_YERPB ;
DR   Q8ZA77, GLGC_YERPE ;  Q1CDL5, GLGC_YERPN ;  A4TQV0, GLGC_YERPP ;
DR   Q664I4, GLGC_YERPS ;  B1JHX9, GLGC_YERPY ;  P55229, GLGL1_ARATH;
DR   P55233, GLGL1_BETVU;  P30524, GLGL1_HORVU;  P55241, GLGL1_MAIZE;
DR   Q00081, GLGL1_SOLTU;  P55236, GLGL1_SPIOL;  P12298, GLGL1_WHEAT;
DR   P55230, GLGL2_ARATH;  P55239, GLGL2_HORVU;  P55234, GLGL2_MAIZE;
DR   P55242, GLGL2_SOLTU;  P12299, GLGL2_WHEAT;  P55231, GLGL3_ARATH;
DR   P55243, GLGL3_SOLTU;  P12300, GLGL3_WHEAT;  Q9SIK1, GLGL4_ARATH;
DR   P52416, GLGS1_VICFA;  P52417, GLGS2_VICFA;  P55228, GLGS_ARATH ;
DR   P55232, GLGS_BETVU ;  Q9M462, GLGS_BRANA ;  P55238, GLGS_HORVU ;
DR   P55240, GLGS_MAIZE ;  P15280, GLGS_ORYSJ ;  Q42882, GLGS_SOLLC ;
DR   P23509, GLGS_SOLTU ;  P55235, GLGS_SPIOL ;  P30523, GLGS_WHEAT ;
//
ID   2.7.7.28
DE   Nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase.
AN   GDP hexose pyrophosphorylase.
AN   GTP:alpha-D-hexose-1-phosphate guanylyltransferase.
AN   Guanosine diphosphohexose pyrophosphorylase.
AN   Hexose 1-phosphate nucleotidyltransferase.
AN   Hexose nucleotidylating enzyme.
AN   Hexose-1-phosphate guanylyltransferase.
AN   NDP-hexose diphosphorylase.
AN   NDP-hexose pyrophosphorylase.
AN   NTP:hexose-1-phosphate nucleotidyltransferase.
AN   Nucleoside diphosphohexose pyrophosphorylase.
AN   Nucleoside-triphosphate-hexose-1-phosphate nucleotidyltransferase.
CA   Nucleoside triphosphate + alpha-D-aldose 1-phosphate = diphosphate + NDP-
CA   hexose.
CC   -!- In decreasing order of activity, guanosine, inosine and adenosine
CC       diphosphate hexoses are substrates in the reverse reaction, with
CC       either glucose or mannose as the sugar.
CC   -!- Formerly EC 2.7.7.29.
//
ID   2.7.7.29
DE   Transferred entry: 2.7.7.28.
//
ID   2.7.7.30
DE   Fucose-1-phosphate guanylyltransferase.
AN   GDP-fucose diphosphorylase.
AN   GDP-fucose pyrophosphorylase.
CA   GTP + beta-L-fucose 1-phosphate = diphosphate + GDP-L-fucose.
DR   Q9LNJ9, FKGP_ARATH ;  O14772, FPGT_HUMAN ;
//
ID   2.7.7.31
DE   DNA nucleotidylexotransferase.
AN   Terminal addition enzyme.
AN   Terminal deoxynucleotidyltransferase.
AN   Terminal deoxyribonucleotidyltransferase.
AN   Terminal transferase.
CA   Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
CC   -!- Catalyzes template-independent extension of the 3'-end of a DNA
CC       strand by one nucleotide at a time.
CC   -!- Cannot initiate a chain de novo.
CC   -!- Nucleoside may be ribo- or deoxyribo-.
PR   PROSITE; PDOC00452;
DR   O57486, TDT_AMBME  ;  P06526, TDT_BOVIN  ;  P36195, TDT_CHICK  ;
DR   A4PCD4, TDT_EULMA  ;  P04053, TDT_HUMAN  ;  O02789, TDT_MONDO  ;
DR   P09838, TDT_MOUSE  ;  Q92089, TDT_ONCMY  ;  P42118, TDT_XENLA  ;
//
ID   2.7.7.32
DE   Galactose-1-phosphate thymidylyltransferase.
AN   dTDP-galactose diphosphorylase.
AN   dTDP-galactose pyrophosphorylase.
CA   dTTP + alpha-D-galactose 1-phosphate = diphosphate + dTDP-galactose.
//
ID   2.7.7.33
DE   Glucose-1-phosphate cytidylyltransferase.
AN   CDP-glucose diphosphorylase.
AN   CDP-glucose pyrophosphorylase.
CA   CTP + alpha-D-glucose 1-phosphate = diphosphate + CDP-glucose.
DR   O06486, RFBF_BACSU ;  Q8Z5I4, RFBF_SALTI ;  P26396, RFBF_SALTY ;
//
ID   2.7.7.34
DE   Glucose-1-phosphate guanylyltransferase.
AN   GDP-glucose diphosphorylase.
AN   GDP-glucose pyrophosphorylase.
CA   GTP + alpha-D-glucose 1-phosphate = diphosphate + GDP-glucose.
CC   -!- Also acts, more slowly, on D-mannose 1-phosphate.
//
ID   2.7.7.35
DE   Ribose-5-phosphate adenylyltransferase.
AN   ADP-ribose phosphorylase.
CA   ADP + D-ribose 5-phosphate = phosphate + ADP-ribose.
//
ID   2.7.7.36
DE   Aldose-1-phosphate adenylyltransferase.
AN   ADP-aldose phosphorylase.
AN   ADP-sugar phosphorylase.
AN   Sugar-1-phosphate adenylyltransferase.
CA   ADP + alpha-D-aldose 1-phosphate = phosphate + ADP-aldose.
//
ID   2.7.7.37
DE   Aldose-1-phosphate nucleotidyltransferase.
AN   NDP-aldose phosphorylase.
AN   NDP-sugar phosphorylase.
AN   Sugar-1-phosphate nucleotidyltransferase.
CA   NDP + alpha-D-aldose 1-phosphate = phosphate + NDP-aldose.
CC   -!- The enzyme works on a variety of alpha-D-aldose 1-phosphates and
CC       beta-L-aldose 1-phosphates (which have the same anomeric
CC       configuration as the former).
//
ID   2.7.7.38
DE   3-deoxy-manno-octulosonate cytidylyltransferase.
AN   CMP-2-keto-3-deoxyoctulosonic acid synthetase.
AN   CMP-3-deoxy-D-manno-octulosonate diphosphorylase.
AN   CMP-3-deoxy-D-manno-octulosonate pyrophosphorylase.
AN   CMP-KDO synthetase.
CA   CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-
CA   octulosonate.
DR   A3MYF7, KDSB1_ACTP2;  B1YVD9, KDSB1_BURA4;  Q0BCH2, KDSB1_BURCM;
DR   B2T6M3, KDSB1_BURPP;  Q39DJ4, KDSB1_BURS3;  Q31H18, KDSB1_THICR;
DR   A3N2M5, KDSB2_ACTP2;  B1Z3N9, KDSB2_BURA4;  Q0B295, KDSB2_BURCM;
DR   B2TAY9, KDSB2_BURPP;  Q39M82, KDSB2_BURS3;  Q31DP4, KDSB2_THICR;
DR   B0BZZ7, KDSB_ACAM1 ;  A1TQ97, KDSB_ACIAC ;  Q6F9X2, KDSB_ACIAD ;
DR   B7H3M4, KDSB_ACIB3 ;  B2HZD0, KDSB_ACIBC ;  Q1IU72, KDSB_ACIBL ;
DR   B0VMY7, KDSB_ACIBS ;  A3M4Z0, KDSB_ACIBT ;  B0VD12, KDSB_ACIBY ;
DR   C1F3B8, KDSB_ACIC5 ;  B9MI81, KDSB_ACIET ;  B7J514, KDSB_ACIF2 ;
DR   B5EMX4, KDSB_ACIF5 ;  A1W894, KDSB_ACISJ ;  B3GZS5, KDSB_ACTP7 ;
DR   B0BRZ1, KDSB_ACTPJ ;  A6VQ31, KDSB_ACTSZ ;  A0KLX9, KDSB_AERHH ;
DR   A4SL70, KDSB_AERS4 ;  B9JGV0, KDSB_AGRRK ;  A9CKP8, KDSB_AGRT5 ;
DR   Q0VQP3, KDSB_ALCBS ;  Q0A8Q5, KDSB_ALHEH ;  B6ES02, KDSB_ALISL ;
DR   B4RYE4, KDSB_ALTMD ;  B8JBN7, KDSB_ANAD2 ;  Q2IH80, KDSB_ANADE ;
DR   A7HIF1, KDSB_ANADF ;  B4UIT7, KDSB_ANASK ;  O66914, KDSB_AQUAE ;
DR   Q5P107, KDSB_AROAE ;  A8IGU8, KDSB_AZOC5 ;  A1K5I4, KDSB_AZOSB ;
DR   Q8A9S0, KDSB_BACTN ;  A6L5J0, KDSB_BACV8 ;  A1UU32, KDSB_BARBK ;
DR   Q6G4U6, KDSB_BARHE ;  Q6G0M4, KDSB_BARQU ;  A9IMZ3, KDSB_BART1 ;
DR   Q6MPP1, KDSB_BDEBA ;  Q7VR47, KDSB_BLOFL ;  Q492T2, KDSB_BLOPB ;
DR   Q2KZE5, KDSB_BORA1 ;  Q7WKU7, KDSB_BORBR ;  Q7W7F9, KDSB_BORPA ;
DR   A9IQ35, KDSB_BORPD ;  Q7VVB0, KDSB_BORPE ;  Q89UJ4, KDSB_BRAJA ;
DR   A5ERZ6, KDSB_BRASB ;  A4YLY9, KDSB_BRASO ;  B2S7U2, KDSB_BRUA1 ;
DR   Q2YPQ5, KDSB_BRUA2 ;  Q57FX6, KDSB_BRUAB ;  A9M6P3, KDSB_BRUC2 ;
DR   C0RGA2, KDSB_BRUMB ;  Q8YEH4, KDSB_BRUME ;  A5VMY8, KDSB_BRUO2 ;
DR   B0CI58, KDSB_BRUSI ;  Q8G3B2, KDSB_BRUSU ;  Q1BU67, KDSB_BURCA ;
DR   B1JXF7, KDSB_BURCC ;  A0K9X0, KDSB_BURCH ;  B4E9G0, KDSB_BURCJ ;
DR   A9AGK2, KDSB_BURM1 ;  A3MN47, KDSB_BURM7 ;  A2S515, KDSB_BURM9 ;
DR   Q62HI2, KDSB_BURMA ;  A1V116, KDSB_BURMS ;  A3NS88, KDSB_BURP0 ;
DR   Q3JVB0, KDSB_BURP1 ;  A3N6K5, KDSB_BURP6 ;  B2JDV2, KDSB_BURP8 ;
DR   Q63WL5, KDSB_BURPS ;  Q2T0K3, KDSB_BURTA ;  A4JH79, KDSB_BURVG ;
DR   Q13UR9, KDSB_BURXL ;  B3PFR9, KDSB_CELJU ;  Q5L5S2, KDSB_CHLAB ;
DR   Q3ATT2, KDSB_CHLCH ;  Q822T3, KDSB_CHLCV ;  Q254V8, KDSB_CHLFF ;
DR   B3EG58, KDSB_CHLL2 ;  Q9PKL1, KDSB_CHLMU ;  B3QL08, KDSB_CHLP8 ;
DR   B3EMY6, KDSB_CHLPB ;  A1BI64, KDSB_CHLPD ;  Q9Z8U9, KDSB_CHLPN ;
DR   B0B9T2, KDSB_CHLT2 ;  B3QTV9, KDSB_CHLT3 ;  Q3KMI0, KDSB_CHLTA ;
DR   B0BBG2, KDSB_CHLTB ;  Q8KBF7, KDSB_CHLTE ;  P0CD75, KDSB_CHLTR ;
DR   Q1QX66, KDSB_CHRSD ;  Q7NSS6, KDSB_CHRVO ;  A8AIG3, KDSB_CITK8 ;
DR   Q483B3, KDSB_COLP3 ;  B6J8F8, KDSB_COXB1 ;  B6J1K0, KDSB_COXB2 ;
DR   A9KEB5, KDSB_COXBN ;  A9NBW9, KDSB_COXBR ;  Q83E52, KDSB_COXBU ;
DR   Q0KE19, KDSB_CUPNH ;  Q475G0, KDSB_CUPPJ ;  B3R0X8, KDSB_CUPTR ;
DR   Q11R71, KDSB_CYTH3 ;  Q47B45, KDSB_DECAR ;  A9BWI2, KDSB_DELAS ;
DR   B8FKL0, KDSB_DESAA ;  Q30V56, KDSB_DESDG ;  A8ZWH0, KDSB_DESOH ;
DR   Q726J3, KDSB_DESVH ;  B8DIL4, KDSB_DESVM ;  A1VA25, KDSB_DESVV ;
DR   A5EW69, KDSB_DICNV ;  A7ZK07, KDSB_ECO24 ;  B7UN04, KDSB_ECO27 ;
DR   B7LE16, KDSB_ECO55 ;  Q8XDG6, KDSB_ECO57 ;  B5YT52, KDSB_ECO5E ;
DR   B7M847, KDSB_ECO8A ;  C4ZQ44, KDSB_ECOBW ;  B1X8M2, KDSB_ECODH ;
DR   A7ZYM0, KDSB_ECOHS ;  Q8FJA9, KDSB_ECOL6 ;  B1IW13, KDSB_ECOLC ;
DR   P04951, KDSB_ECOLI ;  B6I8Z0, KDSB_ECOSE ;  C5BAD7, KDSB_EDWI9 ;
DR   B2KD62, KDSB_ELUMP ;  A4W8T7, KDSB_ENT38 ;  A7MEV1, KDSB_ENTS8 ;
DR   Q6D440, KDSB_ERWCT ;  B2VC71, KDSB_ERWT9 ;  B7LN80, KDSB_ESCF3 ;
DR   A5FBA3, KDSB_FLAJ1 ;  A6GYA2, KDSB_FLAPJ ;  B0U168, KDSB_FRAP2 ;
DR   Q14GD1, KDSB_FRAT1 ;  A7NDA8, KDSB_FRATF ;  Q2A2J8, KDSB_FRATH ;
DR   B2SG51, KDSB_FRATM ;  A0Q5R0, KDSB_FRATN ;  Q0BL48, KDSB_FRATO ;
DR   Q5NEX8, KDSB_FRATT ;  A4IX75, KDSB_FRATW ;  Q8RFA8, KDSB_FUSNN ;
DR   C1A8V7, KDSB_GEMAT ;  B5E8N2, KDSB_GEOBB ;  B3EAK6, KDSB_GEOLS ;
DR   Q39W63, KDSB_GEOMG ;  B9M9Q4, KDSB_GEOSF ;  Q74BY2, KDSB_GEOSL ;
DR   C6E0M8, KDSB_GEOSM ;  A5G5T4, KDSB_GEOUR ;  A0M2E8, KDSB_GRAFK ;
DR   Q7VNY6, KDSB_HAEDU ;  Q4QPI6, KDSB_HAEI8 ;  A5UB81, KDSB_HAEIE ;
DR   A5UFM6, KDSB_HAEIG ;  P44490, KDSB_HAEIN ;  B8F5J5, KDSB_HAEPS ;
DR   Q0I2X5, KDSB_HAES1 ;  B0UT79, KDSB_HAES2 ;  Q2SIN2, KDSB_HAHCH ;
DR   A1WWF7, KDSB_HALHL ;  Q17YX7, KDSB_HELAH ;  B6JKG1, KDSB_HELP2 ;
DR   B5Z9Z7, KDSB_HELPG ;  Q1CUS2, KDSB_HELPH ;  Q9ZMK4, KDSB_HELPJ ;
DR   B2US61, KDSB_HELPS ;  O25016, KDSB_HELPY ;  A4G7X9, KDSB_HERAR ;
DR   Q5QU39, KDSB_IDILO ;  A6T170, KDSB_JANMA ;  B5XY79, KDSB_KLEP3 ;
DR   A6T710, KDSB_KLEP7 ;  Q1MPN4, KDSB_LAWIP ;  Q5X3Y7, KDSB_LEGPA ;
DR   A5ID77, KDSB_LEGPC ;  Q5ZU88, KDSB_LEGPH ;  Q5WVD2, KDSB_LEGPL ;
DR   B0SA58, KDSB_LEPBA ;  Q04VK9, KDSB_LEPBJ ;  Q04XW6, KDSB_LEPBL ;
DR   B0SK97, KDSB_LEPBP ;  B1Y6I6, KDSB_LEPCP ;  Q72UN2, KDSB_LEPIC ;
DR   Q8F0C3, KDSB_LEPIN ;  Q2VZK3, KDSB_MAGSA ;  Q65U18, KDSB_MANSM ;
DR   A1U1F3, KDSB_MARAV ;  Q0AST1, KDSB_MARMM ;  A6VUC8, KDSB_MARMS ;
DR   Q11AX2, KDSB_MESSB ;  B7L043, KDSB_METC4 ;  Q60B47, KDSB_METCA ;
DR   A9VZK8, KDSB_METEP ;  Q1GZI3, KDSB_METFK ;  B8ICG5, KDSB_METNO ;
DR   B1ZJ23, KDSB_METPB ;  A2SIQ3, KDSB_METPP ;  B1LVX5, KDSB_METRJ ;
DR   B0UNK9, KDSB_METS4 ;  Q1DDB3, KDSB_MYXXD ;  Q5F9Y9, KDSB_NEIG1 ;
DR   B4RJR9, KDSB_NEIG2 ;  A9M2V7, KDSB_NEIM0 ;  A1IQS6, KDSB_NEIMA ;
DR   Q9K0D6, KDSB_NEIMB ;  A1KST6, KDSB_NEIMF ;  Q1QR80, KDSB_NITHX ;
DR   Q3J7B0, KDSB_NITOC ;  A6Q3P4, KDSB_NITSB ;  Q3SVY8, KDSB_NITWN ;
DR   A6WUU4, KDSB_OCHA4 ;  B6JJE4, KDSB_OLICO ;  A6L9D4, KDSB_PARD8 ;
DR   A7HPP1, KDSB_PARL1 ;  Q6MD00, KDSB_PARUW ;  P57883, KDSB_PASMU ;
DR   C6DFA4, KDSB_PECCP ;  Q3A370, KDSB_PELCD ;  Q3B604, KDSB_PELLD ;
DR   B4SES6, KDSB_PELPB ;  A1APF8, KDSB_PELPD ;  Q7N6C2, KDSB_PHOLL ;
DR   Q6LPK9, KDSB_PHOPR ;  A1VNK3, KDSB_POLNA ;  B1XTC6, KDSB_POLNS ;
DR   Q129C7, KDSB_POLSJ ;  A4SVI9, KDSB_POLSQ ;  B2RLM4, KDSB_PORG3 ;
DR   Q7MTW6, KDSB_PORGI ;  B4S4I2, KDSB_PROA2 ;  B4ET34, KDSB_PROMH ;
DR   A4SD67, KDSB_PROVI ;  Q48L52, KDSB_PSE14 ;  Q15UY4, KDSB_PSEA6 ;
DR   A6V3B9, KDSB_PSEA7 ;  B7V149, KDSB_PSEA8 ;  Q02PE2, KDSB_PSEAB ;
DR   Q9HZM5, KDSB_PSEAE ;  Q1ICZ9, KDSB_PSEE4 ;  Q4KFT3, KDSB_PSEF5 ;
DR   C3JY27, KDSB_PSEFS ;  Q3IGX8, KDSB_PSEHT ;  A4XSR4, KDSB_PSEMY ;
DR   Q3K8J4, KDSB_PSEPF ;  B0KF43, KDSB_PSEPG ;  Q88LM7, KDSB_PSEPK ;
DR   B1J508, KDSB_PSEPW ;  Q87YF7, KDSB_PSESM ;  Q4ZVY8, KDSB_PSEU2 ;
DR   Q4FS44, KDSB_PSYA2 ;  Q1QBV8, KDSB_PSYCK ;  A1STD0, KDSB_PSYIN ;
DR   A5WF97, KDSB_PSYWF ;  B2UB84, KDSB_RALPJ ;  Q8XWE2, KDSB_RALSO ;
DR   B3PXG0, KDSB_RHIE6 ;  Q2KDX9, KDSB_RHIEC ;  Q1MN23, KDSB_RHIL3 ;
DR   Q98BN3, KDSB_RHILO ;  B5ZWP0, KDSB_RHILW ;  Q92SX6, KDSB_RHIME ;
DR   Q7UI86, KDSB_RHOBA ;  B6IWU1, KDSB_RHOCS ;  Q21TN7, KDSB_RHOFD ;
DR   Q2IZ84, KDSB_RHOP2 ;  Q07K36, KDSB_RHOP5 ;  Q6N3J9, KDSB_RHOPA ;
DR   Q210C0, KDSB_RHOPB ;  Q133H9, KDSB_RHOPS ;  B3QGN5, KDSB_RHOPT ;
DR   Q2RPI7, KDSB_RHORT ;  C3PN96, KDSB_RICAE ;  A8GN86, KDSB_RICAH ;
DR   A8GW69, KDSB_RICB8 ;  Q1RHU5, KDSB_RICBR ;  A8EZ55, KDSB_RICCK ;
DR   Q92I96, KDSB_RICCN ;  Q4ULX8, KDSB_RICFE ;  A8F1E9, KDSB_RICM5 ;
DR   Q9ZDF0, KDSB_RICPR ;  C4K2D9, KDSB_RICPU ;  B0BXB4, KDSB_RICRO ;
DR   A8GRV7, KDSB_RICRS ;  Q68WZ5, KDSB_RICTY ;  A1AXA1, KDSB_RUTMC ;
DR   Q21J11, KDSB_SACD2 ;  B5F1S0, KDSB_SALA4 ;  A9MHW5, KDSB_SALAR ;
DR   Q57R10, KDSB_SALCH ;  B5FQ61, KDSB_SALDC ;  B5QZC2, KDSB_SALEP ;
DR   B5R8K5, KDSB_SALG2 ;  B4TDQ5, KDSB_SALHS ;  B4T152, KDSB_SALNS ;
DR   Q5PGF5, KDSB_SALPA ;  A9N7U4, KDSB_SALPB ;  C0PXV5, KDSB_SALPC ;
DR   B5BBP0, KDSB_SALPK ;  B4TRV0, KDSB_SALSV ;  Q8Z800, KDSB_SALTI ;
DR   Q8ZQC0, KDSB_SALTY ;  A8GCI3, KDSB_SERP5 ;  A1S639, KDSB_SHEAM ;
DR   B8E9F5, KDSB_SHEB2 ;  A3D555, KDSB_SHEB5 ;  A6WNW2, KDSB_SHEB8 ;
DR   A9L3N6, KDSB_SHEB9 ;  Q12MB0, KDSB_SHEDO ;  Q083F6, KDSB_SHEFN ;
DR   B0TVJ0, KDSB_SHEHH ;  A3QE24, KDSB_SHELP ;  Q8EEA9, KDSB_SHEON ;
DR   A8H420, KDSB_SHEPA ;  A4Y7B5, KDSB_SHEPC ;  B8CMP6, KDSB_SHEPW ;
DR   A0KWG8, KDSB_SHESA ;  A8FW10, KDSB_SHESH ;  Q0HJ42, KDSB_SHESM ;
DR   Q0HUU0, KDSB_SHESR ;  A1RJ74, KDSB_SHESW ;  B1KDR7, KDSB_SHEWM ;
DR   B2TUG1, KDSB_SHIB3 ;  Q31YT2, KDSB_SHIBS ;  Q32E38, KDSB_SHIDS ;
DR   Q0SWZ7, KDSB_SHIF8 ;  Q83LN8, KDSB_SHIFL ;  Q3Z3K3, KDSB_SHISS ;
DR   A6UF15, KDSB_SINMW ;  Q2NUA2, KDSB_SODGM ;  Q01T78, KDSB_SOLUE ;
DR   B4SQQ0, KDSB_STRM5 ;  B2FK23, KDSB_STRMK ;  Q2LY80, KDSB_SYNAS ;
DR   Q31KU9, KDSB_SYNE7 ;  A0LE62, KDSB_SYNFM ;  Q5N120, KDSB_SYNP6 ;
DR   C5BL28, KDSB_TERTT ;  B5YGT5, KDSB_THEYD ;  Q3SIR7, KDSB_THIDA ;
DR   B8GR40, KDSB_THISH ;  C4L8W0, KDSB_TOLAT ;  C5CKW0, KDSB_VARPS ;
DR   A1WSH5, KDSB_VEREI ;  A5CVZ7, KDSB_VESOH ;  A5F726, KDSB_VIBC3 ;
DR   Q9KQX2, KDSB_VIBCH ;  C3LNH9, KDSB_VIBCM ;  Q5E0E9, KDSB_VIBF1 ;
DR   B5ETK7, KDSB_VIBFM ;  A7MV12, KDSB_VIBHB ;  Q87R14, KDSB_VIBPA ;
DR   Q8DAU9, KDSB_VIBVU ;  Q7MJ10, KDSB_VIBVY ;  Q8D2V1, KDSB_WIGBR ;
DR   Q7M829, KDSB_WOLSU ;  Q8PKS3, KDSB_XANAC ;  Q3BTC6, KDSB_XANC5 ;
DR   Q4UV63, KDSB_XANC8 ;  B0RSI0, KDSB_XANCB ;  Q8P8W6, KDSB_XANCP ;
DR   Q2P3E9, KDSB_XANOM ;  Q5H0H2, KDSB_XANOR ;  A7IIM9, KDSB_XANP2 ;
DR   B2I6C4, KDSB_XYLF2 ;  Q9PB46, KDSB_XYLFA ;  B0U330, KDSB_XYLFM ;
DR   Q87BW1, KDSB_XYLFT ;  A1JMK9, KDSB_YERE8 ;  A7FJV8, KDSB_YERP3 ;
DR   Q1CA60, KDSB_YERPA ;  B2KA34, KDSB_YERPB ;  Q8ZGA4, KDSB_YERPE ;
DR   A9R7J3, KDSB_YERPG ;  Q1CGH5, KDSB_YERPN ;  A4TN08, KDSB_YERPP ;
DR   Q66CH8, KDSB_YERPS ;  B1JQT6, KDSB_YERPY ;  P42215, KPSU1_ECOLX;
DR   P42216, KPSU5_ECOLX;
//
ID   2.7.7.39
DE   Glycerol-3-phosphate cytidylyltransferase.
AN   CDP-glycerol diphosphorylase.
AN   CDP-glycerol pyrophosphorylase.
CA   CTP + sn-glycerol 3-phosphate = diphosphate + CDP-glycerol.
DR   P27623, TAGD_BACSU ;  Q8RKI6, TARD_BACPZ ;
//
ID   2.7.7.40
DE   D-ribitol-5-phosphate cytidylyltransferase.
AN   CDP-ribitol diphosphorylase.
AN   CDP-ribitol pyrophosphorylase.
CA   CTP + D-ribitol 5-phosphate = diphosphate + CDP-ribitol.
DR   Q8RKI9, TARI_BACPZ ;
//
ID   2.7.7.41
DE   Phosphatidate cytidylyltransferase.
AN   CDP-diacylglycerol synthase.
AN   CDP-diglyceride diphosphorylase.
AN   CDP-diglyceride pyrophosphorylase.
AN   CDP-diglyceride synthetase.
CA   CTP + phosphatidate = diphosphate + CDP-diacylglycerol.
PR   PROSITE; PDOC01019;
DR   O04928, CDS1_ARATH ;  Q95ZE3, CDS1_ENCCU ;  Q92903, CDS1_HUMAN ;
DR   P98191, CDS1_MOUSE ;  O35052, CDS1_RAT   ;  O04940, CDS1_SOLTU ;
DR   P38221, CDS1_YEAST ;  A0JNC1, CDS2_BOVIN ;  O95674, CDS2_HUMAN ;
DR   Q99L43, CDS2_MOUSE ;  Q91XU8, CDS2_RAT   ;  O67292, CDSA_AQUAE ;
DR   O31752, CDSA_BACSU ;  Q2YRP9, CDSA_BRUA2 ;  P0C102, CDSA_BRUAB ;
DR   Q8YHH2, CDSA_BRUME ;  Q8G0E0, CDSA_BRUSU ;  P53439, CDSA_CAEEL ;
DR   Q9PJU1, CDSA_CHLMU ;  Q9Z7Y6, CDSA_CHLPN ;  O84457, CDSA_CHLTR ;
DR   Q55D90, CDSA_DICDI ;  P56079, CDSA_DROME ;  P0ABG2, CDSA_ECO57 ;
DR   P0ABG1, CDSA_ECOLI ;  P44937, CDSA_HAEIN ;  Q9ZML7, CDSA_HELPJ ;
DR   O25004, CDSA_HELPY ;  P63759, CDSA_MYCBO ;  Q49433, CDSA_MYCGE ;
DR   Q9CBU1, CDSA_MYCLE ;  P75160, CDSA_MYCPN ;  P63758, CDSA_MYCTU ;
DR   Q59640, CDSA_PSEAE ;  Q1RII7, CDSA_RICBR ;  Q92I31, CDSA_RICCN ;
DR   Q4ULR7, CDSA_RICFE ;  Q9ZDA8, CDSA_RICPR ;  Q68WV5, CDSA_RICTY ;
DR   P0ABG3, CDSA_SHIFL ;  Q5HGH0, CDSA_STAAC ;  Q99UL1, CDSA_STAAM ;
DR   Q7A5Y4, CDSA_STAAN ;  Q6GHH4, CDSA_STAAR ;  Q6G9V2, CDSA_STAAS ;
DR   Q7A121, CDSA_STAAW ;  Q5HPT0, CDSA_STAEQ ;  Q8CST9, CDSA_STAES ;
DR   Q4L5W3, CDSA_STAHJ ;  Q49X46, CDSA_STAS1 ;  P73548, CDSA_SYNY3 ;
DR   Q9X1B7, CDSA_THEMA ;  Q9P381, CDSH_SCHPO ;
//
ID   2.7.7.42
DE   [Glutamate--ammonia-ligase] adenylyltransferase.
AN   Glutamate-ammonia-ligase adenylyltransferase.
AN   Glutamine-synthetase adenylyltransferase.
CA   ATP + [L-glutamate:ammonia ligase (ADP-forming)] = diphosphate +
CA   adenylyl-[L-glutamate:ammonia ligase (ADP-forming)].
DR   Q6FEI9, GLNE_ACIAD ;  Q8UGQ4, GLNE_AGRT5 ;  B4RTA0, GLNE_ALTMD ;
DR   Q5P7S1, GLNE_AROAE ;  Q6G488, GLNE_BARHE ;  Q6G0B0, GLNE_BARQU ;
DR   B3DS62, GLNE_BIFLD ;  Q8G654, GLNE_BIFLO ;  B7GRV5, GLNE_BIFLS ;
DR   Q7WHH4, GLNE_BORBR ;  Q7W993, GLNE_BORPA ;  Q7VYQ0, GLNE_BORPE ;
DR   Q89QJ5, GLNE_BRAJA ;  A5EGB0, GLNE_BRASB ;  A4YRN0, GLNE_BRASO ;
DR   Q8YG35, GLNE_BRUME ;  Q8G1U0, GLNE_BRUSU ;  Q62HC7, GLNE_BURMA ;
DR   Q63R39, GLNE_BURPS ;  Q9A4S7, GLNE_CAUCR ;  Q7NW95, GLNE_CHRVO ;
DR   A8APT2, GLNE_CITK8 ;  Q6NG61, GLNE_CORDI ;  Q8FNL8, GLNE_COREF ;
DR   Q79VE2, GLNE_CORGL ;  B7UIW1, GLNE_ECO27 ;  B7MAC9, GLNE_ECO45 ;
DR   Q8XBM3, GLNE_ECO57 ;  B5YR92, GLNE_ECO5E ;  B7NJR6, GLNE_ECO7I ;
DR   B7N0K2, GLNE_ECO81 ;  B7LZK2, GLNE_ECO8A ;  C4ZQX0, GLNE_ECOBW ;
DR   B1XG58, GLNE_ECODH ;  A8A4K7, GLNE_ECOHS ;  Q8FDH4, GLNE_ECOL6 ;
DR   B1IRR3, GLNE_ECOLC ;  P30870, GLNE_ECOLI ;  B7ND41, GLNE_ECOLU ;
DR   B6I424, GLNE_ECOSE ;  B1LF44, GLNE_ECOSM ;  Q6D163, GLNE_ERWCT ;
DR   B7LQD0, GLNE_ESCF3 ;  Q7VKZ4, GLNE_HAEDU ;  P44419, GLNE_HAEIN ;
DR   Q2SN48, GLNE_HAHCH ;  Q5QY18, GLNE_IDILO ;  B5XU39, GLNE_KLEP3 ;
DR   A6TE32, GLNE_KLEP7 ;  Q6AFH2, GLNE_LEIXX ;  Q65T25, GLNE_MANSM ;
DR   Q605D9, GLNE_METCA ;  A0QEW1, GLNE_MYCA1 ;  P69941, GLNE_MYCBO ;
DR   Q9CBT4, GLNE_MYCLE ;  B2HHM1, GLNE_MYCMM ;  Q73YJ1, GLNE_MYCPA ;
DR   A0R082, GLNE_MYCS2 ;  P69942, GLNE_MYCTU ;  A0PNH1, GLNE_MYCUA ;
DR   Q9JX72, GLNE_NEIMA ;  Q9K1D5, GLNE_NEIMB ;  Q0AGL4, GLNE_NITEC ;
DR   Q81ZZ7, GLNE_NITEU ;  Q3JES8, GLNE_NITOC ;  Q5YZ84, GLNE_NOCFA ;
DR   Q9FD13, GLNE_PASHA ;  Q9CNQ2, GLNE_PASMU ;  Q7N0C2, GLNE_PHOLL ;
DR   Q6LUZ6, GLNE_PHOPR ;  Q6A9Z4, GLNE_PROAC ;  B4EW47, GLNE_PROMH ;
DR   Q9HUF4, GLNE_PSEAE ;  Q88QZ4, GLNE_PSEPK ;  Q87VD5, GLNE_PSESM ;
DR   A1SRE0, GLNE_PSYIN ;  Q8XW19, GLNE_RALSO ;  Q985F6, GLNE_RHILO ;
DR   Q92R86, GLNE_RHIME ;  Q2IUH4, GLNE_RHOP2 ;  Q6N8H0, GLNE_RHOPA ;
DR   Q139J0, GLNE_RHOPS ;  B3QBR5, GLNE_RHOPT ;  B5F697, GLNE_SALA4 ;
DR   A9MPW2, GLNE_SALAR ;  Q57JQ8, GLNE_SALCH ;  B5FHT6, GLNE_SALDC ;
DR   B5QZ37, GLNE_SALEP ;  B5REF9, GLNE_SALG2 ;  B4TI52, GLNE_SALHS ;
DR   B4T671, GLNE_SALNS ;  Q5PC85, GLNE_SALPA ;  A9N5X9, GLNE_SALPB ;
DR   C0PYX4, GLNE_SALPC ;  B5BG12, GLNE_SALPK ;  B4TVT5, GLNE_SALSV ;
DR   Q8Z3N1, GLNE_SALTI ;  Q8ZLY6, GLNE_SALTY ;  A8GJU4, GLNE_SERP5 ;
DR   A1S909, GLNE_SHEAM ;  Q07Y17, GLNE_SHEFN ;  A3QAK2, GLNE_SHELP ;
DR   Q8EAY1, GLNE_SHEON ;  A8G014, GLNE_SHESH ;  B1KE36, GLNE_SHEWM ;
DR   B2U1F8, GLNE_SHIB3 ;  Q31WY2, GLNE_SHIBS ;  Q32BR1, GLNE_SHIDS ;
DR   Q7UBI7, GLNE_SHIFL ;  Q3YXI9, GLNE_SHISS ;  Q81ZW1, GLNE_STRAW ;
DR   Q8CK02, GLNE_STRCO ;  B4SHL3, GLNE_STRM5 ;  B2FKU9, GLNE_STRMK ;
DR   B8GL43, GLNE_THISH ;  Q9KPD4, GLNE_VIBCH ;  Q87SK0, GLNE_VIBPA ;
DR   Q8DEH6, GLNE_VIBVU ;  Q7MNY4, GLNE_VIBVY ;  Q8PPY3, GLNE_XANAC ;
DR   Q4UZ80, GLNE_XANC8 ;  B0RN79, GLNE_XANCB ;  Q8P4V7, GLNE_XANCP ;
DR   Q2NY41, GLNE_XANOM ;  A7IL55, GLNE_XANP2 ;  A1JQV7, GLNE_YERE8 ;
DR   A7FE78, GLNE_YERP3 ;  Q1C373, GLNE_YERPA ;  B2K2H5, GLNE_YERPB ;
DR   Q8ZI61, GLNE_YERPE ;  A9R7D6, GLNE_YERPG ;  Q1CMD5, GLNE_YERPN ;
DR   A4THT8, GLNE_YERPP ;  Q665V2, GLNE_YERPS ;  B1JM25, GLNE_YERPY ;
//
ID   2.7.7.43
DE   N-acylneuraminate cytidylyltransferase.
AN   CMP-N-acetylneuraminic acid synthetase.
AN   CMP-NeuNAc synthetase.
AN   CMP-sialate diphosphorylase.
AN   CMP-sialate pyrophosphorylase.
AN   CMP-sialate synthase.
AN   CMP-sialic acid synthetase.
CA   CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate.
CC   -!- Acts on N-acetyl- and N-glycolyl- derivatives.
DR   P29188, NEUAX_RAT  ;  Q3SZM5, NEUA_BOVIN ;  P13266, NEUA_ECOLX ;
DR   Q57140, NEUA_HAEIN ;  Q8NFW8, NEUA_HUMAN ;  Q99KK2, NEUA_MOUSE ;
DR   P0A0Z7, NEUA_NEIMB ;  P0A0Z8, NEUA_NEIME ;  Q90WG6, NEUA_ONCMY ;
DR   Q5R6R5, NEUA_PONAB ;  P69060, NEUA_RAT   ;  P0A4V1, NEUA_STRA1 ;
DR   P0A4V0, NEUA_STRA3 ;  Q9AFG9, NEUA_STRA5 ;
//
ID   2.7.7.44
DE   Glucuronate-1-phosphate uridylyltransferase.
CA   UTP + 1-phospho-alpha-D-glucuronate = diphosphate + UDP-glucuronate.
CC   -!- Also acts slowly with CTP.
//
ID   2.7.7.45
DE   Guanosine-triphosphate guanylyltransferase.
CA   2 GTP = diphosphate + P(1),P(4)-bis(5'-guanosyl) tetraphosphate.
CC   -!- Also acts, more slowly, on GDP to form P(1),P(3)-bis(5'-guanosyl)
CC       triphosphate.
//
ID   2.7.7.46
DE   Gentamicin 2''-nucleotidyltransferase.
AN   2''-aminoglycoside nucleotidyltransferase.
CA   Nucleoside triphosphate + gentamicin = diphosphate +
CA   2''-nucleotidylgentamicin.
CC   -!- ATP, dATP, CTP, ITP and GTP can act as donors.
CC   -!- Kanamycin, tobramycin and sisomicin can also act as acceptors.
CC   -!- The nucleotidyl residue is transferred to the 2-hydroxy group of the
CC       3-amino-3-deoxy-D-glucose moiety in the antibiotic.
DR   P0AE05, AADB1_KLEPN;  P29806, AADB2_KLEPN;  P0AE04, AADB_ECOLX ;
//
ID   2.7.7.47
DE   Streptomycin 3''-adenylyltransferase.
CA   ATP + streptomycin = diphosphate + 3''-adenylylstreptomycin.
CC   -!- Also acts on spectinomycin.
DR   P0AG05, S3AD_ECOLX ;  Q07448, S3AD_ENTFA ;  P08881, S3AD_KLEPN ;
DR   P14511, S3AD_SHIFL ;  P0A0D0, S3AD_STAAM ;  P0A0D1, S3AD_STAAN ;
DR   P0A0D2, S3AD_STAAU ;  P0AG06, S3AX_SHIFL ;
//
ID   2.7.7.48
DE   RNA-directed RNA polymerase.
AN   RNA nucleotidyltransferase (RNA-directed).
CA   Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
CC   -!- Catalyzes RNA-template-directed extension of the 3'-end of an RNA
CC       strand by one nucleotide at a time.
CC   -!- Can initiate a chain de novo.
CC   -!- See also EC 2.7.7.6.
PR   PROSITE; PDOC50507;
PR   PROSITE; PDOC51471;
DR   P05080, 194K_TRVSY ;  Q9QSP0, L_ABLVB    ;  Q8JTG9, L_ABLVH    ;
DR   Q6XQI9, L_ALLVP    ;  Q2Y2L8, L_AMPV1    ;  A0PJ24, L_BCNVU    ;
DR   Q8JMN0, L_BDV      ;  P52639, L_BDVV     ;  Q9E784, L_BEFVB    ;
DR   O91940, L_BRSVA    ;  Q8JPR2, L_BUNL8    ;  P20470, L_BUNYW    ;
DR   Q6TQR6, L_CCHFI    ;  P24658, L_CDVO     ;  P13179, L_CHAV     ;
DR   B2C4J3, L_CHAVB    ;  Q6DN67, L_CPSVP    ;  Q6XQH2, L_CPXVB    ;
DR   Q66431, L_DUGBA    ;  A4UHQ2, L_EBLV1    ;  A4UHQ7, L_EBLV2    ;
DR   Q91DD4, L_EBORE    ;  Q8JPX5, L_EBORR    ;  Q66802, L_EBOSM    ;
DR   Q5XX01, L_EBOSU    ;  Q6V1Q2, L_EBOZ5    ;  Q05318, L_EBOZM    ;
DR   Q6Q305, L_EMARV    ;  Q6UY70, L_GTOVV    ;  P23456, L_HANTV    ;
DR   O89344, L_HENDH    ;  Q77SJ8, L_HIRRV    ;  Q6WB93, L_HMPVC    ;
DR   P20894, L_HRSV     ;  P28887, L_HRSVA    ;  O36635, L_HRSVB    ;
DR   Q9IWW8, L_HRSVL    ;  Q82707, L_IHNVO    ;  Q82685, L_IHNVW    ;
DR   Q27YE1, L_IPPYV    ;  Q5K2K3, L_ISFV     ;  Q6XQI4, L_JUNIN    ;
DR   O09705, L_LASSJ    ;  B2MW49, L_LATVB    ;  Q8B0U2, L_LBVAV    ;
DR   Q4W382, L_LNYV3    ;  P14240, L_LYCVA    ;  P14241, L_LYCVW    ;
DR   Q1PD54, L_MABVA    ;  P31352, L_MABVM    ;  Q6UY63, L_MABVO    ;
DR   P35262, L_MABVP    ;  Q1PDC4, L_MABVR    ;  Q6IUF8, L_MACHU    ;
DR   P35975, L_MEASA    ;  Q9WMB3, L_MEASC    ;  P12576, L_MEASE    ;
DR   Q8BCV9, L_MILVL    ;  Q6E0W6, L_MMVR     ;  Q27YE5, L_MOBVC    ;
DR   P0C568, L_MOKV     ;  Q50EW2, L_MPV15    ;  P30929, L_MUMPM    ;
DR   P11205, L_NDVB     ;  Q9DLD3, L_NDVB1    ;  Q997F0, L_NIPAV    ;
DR   Q6XQH7, L_OLVVA    ;  B2MW51, L_PARVP    ;  P35946, L_PHODV    ;
DR   P26676, L_PI2HT    ;  P12577, L_PI3H4    ;  Q6RSS2, L_PIRVV    ;
DR   P27176, L_PUUMH    ;  P0C760, L_PUUMS    ;  Q4F8Z9, L_RABVA    ;
DR   Q66T60, L_RABVB    ;  Q0GBX5, L_RABVD    ;  A3F5L9, L_RABVE    ;
DR   Q8B6J5, L_RABVH    ;  A3RM23, L_RABVI    ;  Q9IPJ5, L_RABVN    ;
DR   P11213, L_RABVP    ;  Q0GBY0, L_RABVR    ;  P16289, L_RABVS    ;
DR   P41357, L_RINDR    ;  P27316, L_RVFVZ    ;  O10378, L_RYSV     ;
DR   Q6UY61, L_SABVB    ;  Q9DUD8, L_SENDA    ;  P06829, L_SENDE    ;
DR   Q06996, L_SENDF    ;  O55528, L_SENDO    ;  P06447, L_SENDZ    ;
DR   P27314, L_SEOU8    ;  Q9QJT4, L_SHRV     ;  P35341, L_SV41     ;
DR   Q88434, L_SV5      ;  Q03396, L_SV5WR    ;  Q91DR9, L_SVCV     ;
DR   P31332, L_SYNV     ;  P20430, L_TACVF    ;  A9JR23, L_TAMVU    ;
DR   Q5GA85, L_TAVCV    ;  P37800, L_TOSV     ;  P28976, L_TSWV1    ;
DR   P33453, L_UUKS     ;  P03523, L_VSIVA    ;  Q8B0H0, L_VSIVC    ;
DR   Q98776, L_VSIVM    ;  Q8B0I0, L_VSIVN    ;  Q8B0H5, L_VSIVS    ;
DR   P13615, L_VSNJH    ;  P16379, L_VSNJO    ;  B2ZDY2, L_WWAVU    ;
DR   Q9JGF2, NS1AB_ANV1 ;  Q67726, NS1AB_HASV1;  Q3ZN06, NS1AB_HASV4;
DR   Q4TWH8, NS1AB_HASV5;  Q9IFX2, NS1AB_HASV8;  Q80KJ7, NS1AB_MASV1;
DR   Q9JH66, NS1AB_OASV1;  Q9JH69, NS1AB_TASV1;  Q9ILI5, NS1AB_TASV2;
DR   Q02941, POL1_APMV  ;  Q6W8W5, POL1_ARMVN ;  P90245, POL1_BAMMN ;
DR   Q04574, POL1_BAYMG ;  Q01206, POL1_BAYMJ ;  Q9YJW3, POL1_BAYMY ;
DR   Q76L40, POL1_BBWVS ;  Q9YJU5, POL1_BPMV  ;  Q8V5E0, POL1_BRAV  ;
DR   P18522, POL1_BRSV  ;  Q8QVV0, POL1_CNSV  ;  P03600, POL1_CPMVS ;
DR   P36312, POL1_CPSMV ;  Q6EWG9, POL1_CRLVP ;  P13025, POL1_GCMV  ;
DR   P29149, POL1_GFLV  ;  P35930, POL1_RCMV  ;  Q6W8W4, POL1_RRVC  ;
DR   Q9WAL8, POL1_SDVS5 ;  Q8B8X3, POL1_TBRVM ;  P29150, POL1_TORVR ;
DR   A1XIP9, POL1_TOTV  ;  Q88893, POL1_TRSVB ;  Q04350, POLB_CHPVE ;
DR   Q9YTU2, POLB_CHPVU ;  Q9YLS4, POLG_AEVCA ;  Q6WQ42, POLG_AEVL2 ;
DR   Q6R325, POLG_AEVVR ;  Q6PLS1, POLG_ASGVK ;  P36309, POLG_ASGVP ;
DR   Q65399, POLG_BCMNN ;  Q288N7, POLG_BECN1 ;  Q8JN60, POLG_BECNB ;
DR   P12915, POLG_BOVEV ;  Q65730, POLG_BSTV1 ;  Q65729, POLG_BSTVG ;
DR   Q6XW15, POLG_BTMV  ;  Q96662, POLG_BVDVC ;  P19711, POLG_BVDVN ;
DR   Q01499, POLG_BVDVS ;  A0AUJ5, POLG_BVY3  ;  P17765, POLG_BYMV  ;
DR   Q8V736, POLG_CACV4 ;  Q1KZ59, POLG_CILVC ;  P19712, POLG_CSFVA ;
DR   P21530, POLG_CSFVB ;  Q65900, POLG_CX16G ;  Q9QF31, POLG_CX16T ;
DR   P22055, POLG_CXA21 ;  P36290, POLG_CXA24 ;  P21404, POLG_CXA9  ;
DR   P08291, POLG_CXB1J ;  Q9YLG5, POLG_CXB2O ;  P03313, POLG_CXB3N ;
DR   Q66282, POLG_CXB3W ;  Q86887, POLG_CXB4E ;  P08292, POLG_CXB4J ;
DR   Q03053, POLG_CXB5P ;  Q9QL88, POLG_CXB6S ;  P20177, POLG_CYVV  ;
DR   P27909, POLG_DEN1B ;  P33478, POLG_DEN1S ;  P17763, POLG_DEN1W ;
DR   P29990, POLG_DEN26 ;  P29991, POLG_DEN27 ;  P14337, POLG_DEN28 ;
DR   P07564, POLG_DEN2J ;  P14340, POLG_DEN2N ;  P12823, POLG_DEN2P ;
DR   Q9WDA6, POLG_DEN2Q ;  Q99D35, POLG_DEN3C ;  Q5UB51, POLG_DEN3I ;
DR   Q6YMS3, POLG_DEN3M ;  P27915, POLG_DEN3P ;  Q6YMS4, POLG_DEN3S ;
DR   P09866, POLG_DEN4D ;  Q2YHF2, POLG_DEN4H ;  Q58HT7, POLG_DEN4P ;
DR   Q5UCB8, POLG_DEN4S ;  Q2YHF0, POLG_DEN4T ;  Q96725, POLG_EBHSG ;
DR   O91734, POLG_EC01F ;  Q9YLJ1, POLG_EC05N ;  Q66474, POLG_EC06C ;
DR   Q66577, POLG_EC09B ;  Q66849, POLG_EC09H ;  P29813, POLG_EC11G ;
DR   Q66575, POLG_EC12T ;  Q9WN78, POLG_EC30B ;  P03304, POLG_EMCV  ;
DR   P17593, POLG_EMCVB ;  P17594, POLG_EMCVD ;  P12296, POLG_ENMGO ;
DR   P27407, POLG_FCVC6 ;  P27408, POLG_FCVF4 ;  P27409, POLG_FCVF9 ;
DR   Q66914, POLG_FCVUR ;  P03306, POLG_FMDV1 ;  P03308, POLG_FMDVA ;
DR   P03305, POLG_FMDVO ;  P03311, POLG_FMDVS ;  P49303, POLG_FMDVZ ;
DR   Q69422, POLG_GBVB  ;  Q8V0N6, POLG_HAV88 ;  Q5Y944, POLG_HAVCF ;
DR   Q67825, POLG_HAVGB ;  A3FMB2, POLG_HAVH2 ;  Q05794, POLG_HAVHA ;
DR   P08617, POLG_HAVHM ;  A5LGW7, POLG_HAVJ8 ;  P06441, POLG_HAVLA ;
DR   P13901, POLG_HAVMB ;  Q9DWR1, POLG_HAVNO ;  P14553, POLG_HAVS2 ;
DR   P26664, POLG_HCV1  ;  Q5I2N3, POLG_HCV6A ;  Q68749, POLG_HCVBB ;
DR   P26663, POLG_HCVBK ;  Q9WMX2, POLG_HCVCO ;  O39929, POLG_HCVED ;
DR   O39927, POLG_HCVEU ;  O39928, POLG_HCVEV ;  P27958, POLG_HCVH  ;
DR   Q81754, POLG_HCVH9 ;  Q913D4, POLG_HCVIN ;  Q03463, POLG_HCVJ1 ;
DR   O92972, POLG_HCVJ4 ;  P26660, POLG_HCVJ6 ;  P26661, POLG_HCVJ8 ;
DR   P26662, POLG_HCVJA ;  Q99IB8, POLG_HCVJF ;  Q68801, POLG_HCVJK ;
DR   Q68798, POLG_HCVJL ;  Q9DHD6, POLG_HCVJP ;  Q00269, POLG_HCVJT ;
DR   Q81495, POLG_HCVK3 ;  Q81258, POLG_HCVNZ ;  Q913V3, POLG_HCVR6 ;
DR   O91936, POLG_HCVSA ;  O92529, POLG_HCVT5 ;  Q81487, POLG_HCVTR ;
DR   P29846, POLG_HCVTW ;  Q9QAX1, POLG_HCVVA ;  O92530, POLG_HCVVN ;
DR   O92531, POLG_HCVVO ;  O92532, POLG_HCVVP ;  P32537, POLG_HE701 ;
DR   Q66478, POLG_HE71B ;  Q66479, POLG_HE71M ;  Q66578, POLG_HPE1H ;
DR   Q9YID8, POLG_HPE23 ;  O73556, POLG_HPE2W ;  P03303, POLG_HRV14 ;
DR   Q82122, POLG_HRV16 ;  P12916, POLG_HRV1B ;  P04936, POLG_HRV2  ;
DR   P07210, POLG_HRV8A ;  P27395, POLG_JAEV1 ;  P19110, POLG_JAEV5 ;
DR   P32886, POLG_JAEVJ ;  P14335, POLG_KUNJM ;  P29837, POLG_LANVT ;
DR   P22338, POLG_LIV   ;  P89876, POLG_LMV0  ;  P31999, POLG_LMVE  ;
DR   P54634, POLG_LORDV ;  P33515, POLG_MCFA  ;  P32652, POLG_MDMV  ;
DR   Q91TW9, POLG_MRFVC ;  P05769, POLG_MVEV5 ;  Q83883, POLG_NVN68 ;
DR   P20234, POLG_OMV   ;  P07993, POLG_PEMV  ;  Q01500, POLG_PEMVC ;
DR   O56075, POLG_PEMVM ;  Q9QEJ5, POLG_PESV  ;  O41174, POLG_PEV9U ;
DR   P03300, POLG_POL1M ;  P03301, POLG_POL1S ;  P06210, POLG_POL2L ;
DR   P23069, POLG_POL2W ;  P06209, POLG_POL32 ;  P03302, POLG_POL3L ;
DR   Q04538, POLG_POWVL ;  P13529, POLG_PPVD  ;  Q01681, POLG_PPVEA ;
DR   P17766, POLG_PPVNA ;  P17767, POLG_PPVRA ;  Q84934, POLG_PPVSK ;
DR   Q01901, POLG_PRSVH ;  P19723, POLG_PRSVP ;  P19724, POLG_PRSVW ;
DR   P29152, POLG_PSBMV ;  Q85197, POLG_PVMA  ;  P21294, POLG_PVYCH ;
DR   Q02963, POLG_PVYHU ;  P18247, POLG_PVYN  ;  P11897, POLG_PVYYO ;
DR   Q05057, POLG_PYFV1 ;  O11436, POLG_RGMVD ;  P27411, POLG_RHDV3 ;
DR   Q86119, POLG_RHDVA ;  Q89273, POLG_RHDVB ;  P27410, POLG_RHDVF ;
DR   Q86117, POLG_RHDVS ;  Q83034, POLG_RTSVA ;  Q91PP5, POLG_RTSVT ;
DR   Q90069, POLG_SBMVG ;  P21231, POLG_SBMVN ;  P36286, POLG_SMSV1 ;
DR   P36287, POLG_SMSV4 ;  Q04544, POLG_SOUV3 ;  P89201, POLG_SPMMV ;
DR   P09732, POLG_STEVM ;  P25242, POLG_SUMVS ;  P16604, POLG_SVDVH ;
DR   P13900, POLG_SVDVU ;  Q6XDK8, POLG_SVM10 ;  Q69014, POLG_SVM93 ;
DR   Q672I1, POLG_SVSAP ;  P22556, POLG_TAMV  ;  Q01299, POLG_TBEVH ;
DR   P07720, POLG_TBEVS ;  P14336, POLG_TBEVW ;  P04517, POLG_TEV   ;
DR   P08544, POLG_TMEVB ;  P13899, POLG_TMEVD ;  P08545, POLG_TMEVG ;
DR   A4KZ49, POLG_TRIMV ;  P89509, POLG_TUMVJ ;  Q02597, POLG_TUMVQ ;
DR   P09814, POLG_TVMV  ;  Q9DUN3, POLG_VESVA ;  P20235, POLG_WMV2A ;
DR   Q89251, POLG_WMV2T ;  P18478, POLG_WMV2U ;  P06935, POLG_WNV   ;
DR   P03314, POLG_YEFV1 ;  Q6DV88, POLG_YEFVA ;  Q6J3P1, POLG_YEFVC ;
DR   Q074N0, POLG_YEFVE ;  Q89277, POLG_YEFVF ;  Q98803, POLG_YEFVI ;
DR   Q1X881, POLG_YEFVN ;  Q9YRV3, POLG_YEFVT ;  Q1X880, POLG_YEFVU ;
DR   P18479, POLG_ZYMVC ;  Q89330, POLG_ZYMVR ;  O36979, POLG_ZYMVS ;
DR   Q6QLN1, POLN_AHEV  ;  Q86924, POLN_AURAV ;  P87515, POLN_BFV   ;
DR   Q5XXP4, POLN_CHIK3 ;  Q8JUX6, POLN_CHIKS ;  Q9IJX4, POLN_CRPVC ;
DR   O36966, POLN_DCVEB ;  Q306W6, POLN_EEEV1 ;  Q306W8, POLN_EEEV8 ;
DR   Q4QXJ8, POLN_EEEVF ;  P36327, POLN_EEVV3 ;  Q8V294, POLN_EEVVC ;
DR   Q9WJC7, POLN_EEVVM ;  P36328, POLN_EEVVP ;  P27282, POLN_EEVVT ;
DR   Q5Y389, POLN_GETV  ;  P29324, POLN_HEVBU ;  Q81862, POLN_HEVCH ;
DR   Q9IVZ9, POLN_HEVCT ;  Q9WC28, POLN_HEVHY ;  Q03495, POLN_HEVME ;
DR   Q6J8G2, POLN_HEVMG ;  Q04610, POLN_HEVMY ;  P33424, POLN_HEVPA ;
DR   Q9YLR1, POLN_HEVUS ;  Q8QZ73, POLN_MAYAB ;  P03318, POLN_MIDDV ;
DR   P13886, POLN_ONNVG ;  O90370, POLN_ONNVI ;  O90368, POLN_ONNVS ;
DR   P13887, POLN_RRVN  ;  P13888, POLN_RRVT  ;  Q6X2U4, POLN_RUBVB ;
DR   Q6X2U2, POLN_RUBVC ;  Q9J6K9, POLN_RUBVD ;  Q86500, POLN_RUBVM ;
DR   Q8BCR0, POLN_RUBVN ;  Q99IE7, POLN_RUBVO ;  O40955, POLN_RUBVR ;
DR   P13889, POLN_RUBVT ;  Q99IE5, POLN_RUBVV ;  Q9JGL0, POLN_SAGV  ;
DR   P08411, POLN_SFV   ;  P27283, POLN_SINDO ;  P03317, POLN_SINDV ;
DR   Q8QL53, POLN_SLDV  ;  Q8JJX1, POLN_SPDV  ;  P13896, POLN_WEEV  ;
DR   P35928, POLR_ELV   ;  P20126, POLR_EPMV  ;  P36304, POLR_KYMVJ ;
DR   Q27YG9, POLR_NORAV ;  P20127, POLR_OYMV  ;  P36352, POLR_PHMV  ;
DR   P10358, POLR_TYMV  ;  P20128, POLR_TYMVA ;  P28477, POLR_TYMVC ;
DR   P0C6W1, R1AB_BC133 ;  P0C6V9, R1AB_BC279 ;  P0C6W0, R1AB_BC512 ;
DR   P0C6W2, R1AB_BCHK3 ;  P0C6W3, R1AB_BCHK4 ;  P0C6W4, R1AB_BCHK5 ;
DR   P0C6W5, R1AB_BCHK9 ;  P0C6W6, R1AB_BCRP3 ;  P0C6V7, R1AB_BEV   ;
DR   P0C6V8, R1AB_BRV1  ;  Q08534, R1AB_BYVU  ;  P0C6W7, R1AB_CVBEN ;
DR   P0C6W8, R1AB_CVBLU ;  P0C6W9, R1AB_CVBM  ;  P0C6X0, R1AB_CVBQ  ;
DR   P0C6X1, R1AB_CVH22 ;  P0C6X2, R1AB_CVHN1 ;  P0C6X3, R1AB_CVHN2 ;
DR   P0C6X4, R1AB_CVHN5 ;  P0C6X5, R1AB_CVHNL ;  P0C6X6, R1AB_CVHOC ;
DR   P0C6X7, R1AB_CVHSA ;  P0C6X8, R1AB_CVM2  ;  P0C6X9, R1AB_CVMA5 ;
DR   P0C6Y0, R1AB_CVMJH ;  P0C6Y5, R1AB_CVPPU ;  Q9WQ77, R1AB_CVRSD ;
DR   Q9WQ76, R1AB_CVTMI ;  Q98VG9, R1AB_FIPV  ;  O71189, R1AB_GLRV3 ;
DR   P0C6Y1, R1AB_IBVB  ;  P0C6Y2, R1AB_IBVBC ;  P0C6Y3, R1AB_IBVM  ;
DR   Q83045, R1AB_LIYV9 ;  P0C6Y4, R1AB_PEDV7 ;  Q008X6, R1AB_WBV24 ;
DR   Q9LQV2, RDR1_ARATH ;  Q0DXS3, RDR1_ORYSJ ;  O14227, RDR1_SCHPO ;
DR   O82504, RDR2_ARATH ;  Q7XM31, RDR2_ORYSJ ;  O82190, RDR3_ARATH ;
DR   Q5QMN5, RDR3_ORYSJ ;  O82189, RDR4_ARATH ;  Q5QMN4, RDR4_ORYSJ ;
DR   O82188, RDR5_ARATH ;  Q9SG02, RDR6_ARATH ;  P54891, RDRP_ACLSA ;
DR   P27738, RDRP_ACLSP ;  Q9DIC5, RDRP_AHNNV ;  O70695, RDRP_AHSV9 ;
DR   Q85055, RDRP_AHV2H ;  P03593, RDRP_AMVLE ;  Q2Y0E9, RDRP_APRVF ;
DR   Q8VA42, RDRP_AQRVA ;  Q8JU61, RDRP_AQRVC ;  B2BNE0, RDRP_AQRVG ;
DR   Q64962, RDRP_ASPVP ;  Q9INJ1, RDRP_BAVJK ;  P27462, RDRP_BBMV  ;
DR   Q96631, RDRP_BBV   ;  P03594, RDRP_BMV   ;  Q65667, RDRP_BNYVS ;
DR   Q992J0, RDRP_BOOLV ;  Q9DRA1, RDRP_BOTVF ;  Q6YNQ7, RDRP_BOTVX ;
DR   P09674, RDRP_BPBZ1 ;  P15965, RDRP_BPFR  ;  P07393, RDRP_BPGA  ;
DR   P34701, RDRP_BPJP3 ;  P00585, RDRP_BPMS2 ;  O64308, RDRP_BPMX1 ;
DR   P11124, RDRP_BPPH6 ;  P14647, RDRP_BPQBE ;  P09675, RDRP_BPSP  ;
DR   Q80873, RDRP_BSMV  ;  Q8AZL8, RDRP_BSNV  ;  P13840, RDRP_BTV10 ;
DR   P29044, RDRP_BYDV1 ;  P09505, RDRP_BYDVP ;  P29045, RDRP_BYDVR ;
DR   Q9J5U7, RDRP_CARMS ;  P04518, RDRP_CARMV ;  P20179, RDRP_CCMV  ;
DR   Q0PW25, RDRP_CFMVN ;  P69514, RDRP_CGMVS ;  P69515, RDRP_CGMVW ;
DR   Q91QZ3, RDRP_CLBVS ;  O39436, RDRP_CMVAS ;  Q66136, RDRP_CMVB  ;
DR   P16490, RDRP_CMVFN ;  Q83262, RDRP_CMVII ;  Q66117, RDRP_CMVIX ;
DR   Q86783, RDRP_CMVK  ;  Q96711, RDRP_CMVKO ;  Q66145, RDRP_CMVMB ;
DR   O40977, RDRP_CMVNT ;  P06012, RDRP_CMVQ  ;  Q83265, RDRP_CMVY  ;
DR   P15187, RDRP_CNV   ;  Q33339, RDRP_CPMV1 ;  O15925, RDRP_CPVKS ;
DR   Q66096, RDRP_CRSVL ;  P17459, RDRP_CRV   ;  Q9DSQ0, RDRP_CTFVL ;
DR   P37987, RDRP_CVB   ;  P27153, RDRP_DHVI1 ;  Q91CD5, RDRP_DXV96 ;
DR   Q698V5, RDRP_ESRV9 ;  Q8JYK1, RDRP_FDVS  ;  Q66929, RDRP_FHV   ;
DR   P22168, RDRP_FXMV  ;  Q8UZB6, RDRP_GFKVM ;  Q993M1, RDRP_GGNNV ;
DR   Q67653, RDRP_GLVWB ;  Q67683, RDRP_GRVMC ;  Q67704, RDRP_GVAIS ;
DR   Q67724, RDRP_HASV  ;  Q50LE4, RDRP_HPBVH ;  O57044, RDRP_HV19S ;
DR   Q9IQ46, RDRP_I000X ;  Q8QPH4, RDRP_I00A0 ;  Q289L9, RDRP_I00A1 ;
DR   Q809M3, RDRP_I01A0 ;  Q809M7, RDRP_I01A1 ;  Q809M5, RDRP_I01A2 ;
DR   Q809L9, RDRP_I01A3 ;  Q6DNS6, RDRP_I02A1 ;  Q6DNS5, RDRP_I02A2 ;
DR   Q6DNS4, RDRP_I02A3 ;  Q6DNS3, RDRP_I02A4 ;  Q6J847, RDRP_I02A5 ;
DR   Q6DNS2, RDRP_I02A6 ;  Q6DNQ9, RDRP_I02A7 ;  Q6J856, RDRP_I03A0 ;
DR   Q6DNQ5, RDRP_I03A1 ;  Q2LFH3, RDRP_I05A1 ;  B4URE4, RDRP_I06A0 ;
DR   A8C8K2, RDRP_I07A0 ;  Q3HM40, RDRP_I18A0 ;  P03430, RDRP_I33A0 ;
DR   P03431, RDRP_I34A1 ;  A4GCM7, RDRP_I35A3 ;  A4GCJ4, RDRP_I36A0 ;
DR   Q0HD52, RDRP_I40A0 ;  A4GCL6, RDRP_I43A0 ;  A4U6W0, RDRP_I45A0 ;
DR   Q82571, RDRP_I47A0 ;  Q0A440, RDRP_I49A1 ;  A4U7B4, RDRP_I51A0 ;
DR   A4K151, RDRP_I54A2 ;  P16502, RDRP_I56A0 ;  Q20P14, RDRP_I56A1 ;
DR   Q0A429, RDRP_I56A2 ;  Q1K9Q5, RDRP_I57A0 ;  P26119, RDRP_I57A1 ;
DR   P26120, RDRP_I57A2 ;  P26121, RDRP_I57A3 ;  P16511, RDRP_I57A5 ;
DR   Q0A2G8, RDRP_I59A0 ;  P21426, RDRP_I60A0 ;  B3EUR4, RDRP_I61A1 ;
DR   Q0A2D9, RDRP_I66A0 ;  Q0A451, RDRP_I66A1 ;  Q6XU19, RDRP_I67A0 ;
DR   A8C8X1, RDRP_I67A2 ;  Q0A461, RDRP_I68A3 ;  Q910D6, RDRP_I68A4 ;
DR   P16506, RDRP_I68A5 ;  P03432, RDRP_I68A6 ;  Q6XT06, RDRP_I69A0 ;
DR   Q6XT02, RDRP_I70A0 ;  Q3YPY7, RDRP_I71A1 ;  Q1K9E3, RDRP_I72A2 ;
DR   Q463W7, RDRP_I72A3 ;  Q2ICQ2, RDRP_I72A4 ;  P16504, RDRP_I73A4 ;
DR   Q1PUD1, RDRP_I73A5 ;  P26118, RDRP_I73A6 ;  Q30NP3, RDRP_I75A0 ;
DR   P31341, RDRP_I75A3 ;  Q2RF98, RDRP_I76A6 ;  Q9EA41, RDRP_I77A4 ;
DR   A4GBY5, RDRP_I77AA ;  Q1WP01, RDRP_I77AB ;  P16512, RDRP_I77AD ;
DR   P16503, RDRP_I77AF ;  P16508, RDRP_I78A3 ;  Q2VNE5, RDRP_I78A7 ;
DR   Q2VNC5, RDRP_I78A8 ;  Q0A3Q1, RDRP_I78AC ;  P18882, RDRP_I79A4 ;
DR   Q20PL6, RDRP_I79A7 ;  Q2VC92, RDRP_I80A2 ;  Q2RCG8, RDRP_I80A4 ;
DR   Q08II5, RDRP_I80A6 ;  P16513, RDRP_I80A8 ;  A4GCK5, RDRP_I80AA ;
DR   Q20NV3, RDRP_I80AD ;  P16510, RDRP_I81A4 ;  P26144, RDRP_I82A2 ;
DR   P16509, RDRP_I82A4 ;  A4GCI3, RDRP_I83A1 ;  Q0A2F7, RDRP_I83A4 ;
DR   Q0A2H9, RDRP_I83A5 ;  Q0A2D0, RDRP_I83A6 ;  Q38SQ0, RDRP_I83A8 ;
DR   Q0A2Q6, RDRP_I85A3 ;  P16505, RDRP_I86A3 ;  P16507, RDRP_I88A3 ;
DR   P16514, RDRP_I88A7 ;  O91741, RDRP_I93A0 ;  Q9Q0V0, RDRP_I96A0 ;
DR   A3DRP8, RDRP_I96A2 ;  Q07FH7, RDRP_I96A3 ;  O89749, RDRP_I97A0 ;
DR   Q9WLS3, RDRP_I97A1 ;  Q9Q6Q5, RDRP_IBDV  ;  P31817, RDRP_IBDV5 ;
DR   P12918, RDRP_IBDVA ;  A7L9Z4, RDRP_IBDVB ;  Q82630, RDRP_IBDVU ;
DR   Q918W3, RDRP_ICRSV ;  P13871, RDRP_INBAC ;  P13872, RDRP_INBAD ;
DR   P07832, RDRP_INBLE ;  O36430, RDRP_INBP9 ;  Q6I7C3, RDRP_INCAA ;
DR   Q9IMP4, RDRP_INCJH ;  P19703, RDRP_INCJJ ;  P22173, RDRP_IPNVJ ;
DR   P22174, RDRP_IPNVS ;  Q8V3T6, RDRP_ISAVC ;  Q91IE0, RDRP_LDCPR ;
DR   B1PS76, RDRP_LOLV  ;  Q02382, RDRP_LRVLG ;  P27328, RDRP_LSV   ;
DR   P27327, RDRP_LVX   ;  Q9YPD5, RDRP_MBVLF ;  P11640, RDRP_MCMVK ;
DR   Q1I0V0, RDRP_MPRVN ;  Q6XNL5, RDRP_MRNV  ;  Q7TDB6, RDRP_MYRV9 ;
DR   Q9YRB3, RDRP_NCBVS ;  P15095, RDRP_NMV   ;  Q9IMM4, RDRP_NODAM ;
DR   Q83927, RDRP_OCSVU ;  Q83944, RDRP_OLV2I ;  P89659, RDRP_ORSVC ;
DR   Q84133, RDRP_ORSVS ;  B3VML1, RDRP_OUMVV ;  Q07518, RDRP_P1AMV ;
DR   Q9J7Z2, RDRP_PAV   ;  Q84687, RDRP_PCV87 ;  Q8JVC2, RDRP_PCVC  ;
DR   P29154, RDRP_PEMVW ;  P17520, RDRP_PLRV1 ;  P11623, RDRP_PLRVW ;
DR   P89657, RDRP_PMMVJ ;  P29098, RDRP_PMMVS ;  Q9QBU0, RDRP_PMTVS ;
DR   P20951, RDRP_PMV   ;  P89034, RDRP_PMVK  ;  Q5NDM9, RDRP_PNLV  ;
DR   Q9IWA0, RDRP_POLVP ;  Q3KSM3, RDRP_PRV   ;  P28727, RDRP_PSVJ  ;
DR   P17965, RDRP_PVMR  ;  P22657, RDRP_PVSP  ;  P09395, RDRP_PVX   ;
DR   P22591, RDRP_PVXCP ;  Q07630, RDRP_PVXHB ;  P17779, RDRP_PVXX3 ;
DR   Q9DUT2, RDRP_PZSVT ;  Q05983, RDRP_RBDVR ;  P22956, RDRP_RCNMV ;
DR   Q02119, RDRP_RDVA  ;  Q98631, RDRP_RDVF  ;  P17378, RDRP_REOVD ;
DR   P17377, RDRP_REOVJ ;  P17376, RDRP_REOVL ;  A4PBP6, RDRP_RGDV  ;
DR   Q3ZK55, RDRP_ROT41 ;  B1NKR3, RDRP_ROTAD ;  A9Q1K7, RDRP_ROTB2 ;
DR   A7J398, RDRP_ROTBN ;  P21615, RDRP_ROTBU ;  P35942, RDRP_ROTGI ;
DR   A4ZCW2, RDRP_ROTH3 ;  B2BMQ6, RDRP_ROTH6 ;  B1NKQ9, RDRP_ROTH7 ;
DR   Q91E95, RDRP_ROTHC ;  A7J3A6, RDRP_ROTHD ;  Q9QNB3, RDRP_ROTHK ;
DR   A3DSK5, RDRP_ROTHL ;  B1NKS9, RDRP_ROTHP ;  A7J390, RDRP_ROTHS ;
DR   B1NKT7, RDRP_ROTHT ;  A4ZCW8, RDRP_ROTHW ;  Q45UG0, RDRP_ROTJ1 ;
DR   P26190, RDRP_ROTPC ;  P17699, RDRP_ROTPG ;  Q85036, RDRP_ROTPY ;
DR   P17468, RDRP_ROTRF ;  P22678, RDRP_ROTS1 ;  A2T3S0, RDRP_ROTSH ;
DR   O37061, RDRP_ROTSP ;  B3F2X5, RDRP_ROTTU ;  B2BMF7, RDRP_ROTW3 ;
DR   B1NKU1, RDRP_ROTWI ;  A7J3A2, RDRP_ROTYO ;  O92604, RDRP_RRSVT ;
DR   Q85431, RDRP_RSVT  ;  O72157, RDRP_SBMVA ;  Q89249, RDRP_SBWMN ;
DR   P21405, RDRP_SCPMV ;  P25328, RDRP_SCV20 ;  Q07048, RDRP_SCV23 ;
DR   Q87022, RDRP_SCVLA ;  P23172, RDRP_SCVLB ;  P89202, RDRP_SHMV  ;
DR   Q04575, RDRP_SHVX  ;  Q9QAZ8, RDRP_SJNNV ;  P28897, RDRP_SMYEA ;
DR   Q6YI57, RDRP_SSDRV ;  P29035, RDRP_TAV   ;  P15962, RDRP_TBSVC ;
DR   P17460, RDRP_TCV   ;  O41353, RDRP_THOGV ;  P18339, RDRP_TMGMV ;
DR   P90211, RDRP_TMOB  ;  P03586, RDRP_TMV   ;  Q9YQ08, RDRP_TMVB  ;
DR   P30738, RDRP_TMVKR ;  O93058, RDRP_TMVOM ;  Q98745, RDRP_TMVRA ;
DR   P22958, RDRP_TNVA  ;  P27209, RDRP_TNVD  ;  P89678, RDRP_TOBSV ;
DR   Q9Q1T8, RDRP_TOMK1 ;  P89676, RDRP_TOMK2 ;  P03587, RDRP_TOML  ;
DR   Q9YKD6, RDRP_TOMS1 ;  Q9J942, RDRP_TRVPP ;  Q88920, RDRP_TVCV  ;
DR   P09507, RDRP_TYYVF ;  Q64FP0, RDRP_WCCVB ;  P09498, RDRP_WCMVM ;
DR   P15402, RDRP_WCMVO ;  Q66220, RDRP_YOMV  ;  P24928, RPB1_HUMAN ;
DR   P19811, RPOA_EAVBU ;  Q06502, RPOA_LDVC  ;  Q83017, RPOA_LDVP  ;
DR   Q9YN02, RPOA_PRRS1 ;  Q8B912, RPOA_PRRSB ;  Q04561, RPOA_PRRSL ;
DR   Q9WJB2, RPOA_PRRSR ;  A0MD28, RPOA_PRRSS ;  Q68772, RPOA_SHFV  ;
DR   Q8LHH9, SHL2_ORYSJ ;
//
ID   2.7.7.49
DE   RNA-directed DNA polymerase.
AN   DNA nucleotidyltransferase (RNA-directed).
AN   Reverse transcriptase.
AN   Revertase.
CA   Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
CC   -!- Catalyzes RNA-template-directed extension of the 3'-end of a DNA
CC       strand by one deoxynucleotide at a time.
CC   -!- Cannot initiate a chain de novo.
CC   -!- Requires a RNA or DNA primer.
CC   -!- DNA can also serve as template.
CC   -!- See also EC 2.7.7.7.
PR   PROSITE; PDOC50878;
DR   Q64898, DPOL_ASHV  ;  P03162, DPOL_DHBV1 ;  P0C691, DPOL_DHBV3 ;
DR   Q66403, DPOL_DHBVQ ;  P03161, DPOL_GSHV  ;  P03158, DPOL_HBVA2 ;
DR   P03159, DPOL_HBVA3 ;  P17100, DPOL_HBVA4 ;  Q02314, DPOL_HBVA5 ;
DR   Q91C36, DPOL_HBVA6 ;  O91533, DPOL_HBVA7 ;  Q4R1S7, DPOL_HBVA8 ;
DR   Q4R1R9, DPOL_HBVA9 ;  P17394, DPOL_HBVB1 ;  P17393, DPOL_HBVB2 ;
DR   Q9QAB8, DPOL_HBVB3 ;  P17395, DPOL_HBVB4 ;  Q9PX62, DPOL_HBVB5 ;
DR   Q67925, DPOL_HBVB6 ;  Q9QBF1, DPOL_HBVB7 ;  P0C676, DPOL_HBVB8 ;
DR   Q9E6S5, DPOL_HBVC0 ;  P0C688, DPOL_HBVC1 ;  Q9YZR5, DPOL_HBVC2 ;
DR   P12933, DPOL_HBVC3 ;  P31870, DPOL_HBVC4 ;  P03157, DPOL_HBVC5 ;
DR   Q913A7, DPOL_HBVC7 ;  Q81165, DPOL_HBVC8 ;  P0C690, DPOL_HBVC9 ;
DR   Q69028, DPOL_HBVCJ ;  P12900, DPOL_HBVCP ;  P03155, DPOL_HBVD1 ;
DR   P24024, DPOL_HBVD2 ;  P03156, DPOL_HBVD3 ;  Q9QMI1, DPOL_HBVD4 ;
DR   P0C679, DPOL_HBVD5 ;  Q67878, DPOL_HBVD6 ;  O56655, DPOL_HBVD7 ;
DR   Q69602, DPOL_HBVE1 ;  Q80IU7, DPOL_HBVE2 ;  Q9QAW8, DPOL_HBVE3 ;
DR   Q80IU4, DPOL_HBVE4 ;  Q05486, DPOL_HBVF1 ;  Q8JMY4, DPOL_HBVF2 ;
DR   Q99HS4, DPOL_HBVF3 ;  Q99HR5, DPOL_HBVF4 ;  Q69605, DPOL_HBVF6 ;
DR   Q8QZQ2, DPOL_HBVG2 ;  Q9IBI4, DPOL_HBVG3 ;  P87744, DPOL_HBVGB ;
DR   Q9YPV8, DPOL_HBVGO ;  Q8JMY7, DPOL_HBVH1 ;  Q8JN08, DPOL_HBVH2 ;
DR   Q8JMZ7, DPOL_HBVH3 ;  Q9J5S2, DPOL_HBVOR ;  P13846, DPOL_HHBV  ;
DR   P17192, DPOL_HPBDB ;  P30028, DPOL_HPBDC ;  P17193, DPOL_HPBDW ;
DR   P03160, DPOL_WHV1  ;  P06275, DPOL_WHV2  ;  P12899, DPOL_WHV3  ;
DR   P12898, DPOL_WHV4  ;  P17396, DPOL_WHV5  ;  P11292, DPOL_WHV6  ;
DR   O71304, DPOL_WMHBV ;  P0A3U0, LTRA_LACLC ;  P0A3U1, LTRA_LACLM ;
DR   Q03269, PO11_NASVI ;  Q03276, PO11_POPJA ;  Q03277, PO11_SCICO ;
DR   Q03270, PO12_NASVI ;  Q03271, PO13_NASVI ;  Q03272, PO14_NASVI ;
DR   Q03278, PO21_NASVI ;  Q03273, PO21_POPJA ;  Q03279, PO21_SCICO ;
DR   Q03274, PO22_POPJA ;  Q05118, PO23_POPJA ;  Q03275, PO24_POPJA ;
DR   P10266, POK10_HUMAN;  P63135, POK12_HUMAN;  P63136, POK17_HUMAN;
DR   Q9UQG0, POK20_HUMAN;  Q9BXR3, POK2_HUMAN ;  Q9WJR5, POK3_HUMAN ;
DR   P63128, POK4_HUMAN ;  P63132, POK5_HUMAN ;  P63133, POK6_HUMAN ;
DR   Q9QC07, POK7_HUMAN ;  P10399, POL1_CHICK ;  P10400, POL1_MOUSE ;
DR   P20825, POL2_DROME ;  P11369, POL2_MOUSE ;  P04323, POL3_DROME ;
DR   P10394, POL4_DROME ;  Q8I7P9, POL5_DROME ;  Q91DM0, POLG_PVCV1 ;
DR   Q6XKE6, POLG_PVCV2 ;  P16423, POLR_DROME ;  P10978, POLX_TOBAC ;
DR   P10401, POLY_DROME ;  Q7SQ98, POL_ALV    ;  P03360, POL_AVIRE  ;
DR   P10272, POL_BAEVM  ;  P19560, POL_BIV29  ;  P25059, POL_BLVAU  ;
DR   P03361, POL_BLVJ   ;  P33459, POL_CAEVC  ;  P03555, POL_CAMVC  ;
DR   P03556, POL_CAMVD  ;  Q02964, POL_CAMVE  ;  Q00962, POL_CAMVN  ;
DR   P03554, POL_CAMVS  ;  P05400, POL_CERV   ;  P19199, POL_COYMV  ;
DR   Q89703, POL_CSVMV  ;  Q7TD08, POL_CYLCV  ;  P11204, POL_EIAV9  ;
DR   P32542, POL_EIAVC  ;  P03371, POL_EIAVY  ;  P31792, POL_FENV1  ;
DR   O93209, POL_FFV    ;  P16088, POL_FIVPE  ;  P19028, POL_FIVSD  ;
DR   P31822, POL_FIVT2  ;  P10273, POL_FLV    ;  P09523, POL_FMVD   ;
DR   P14350, POL_FOAMV  ;  P21414, POL_GALV   ;  P03362, POL_HTL1A  ;
DR   P14078, POL_HTL1C  ;  P0C211, POL_HTL1L  ;  Q0R5R2, POL_HTL32  ;
DR   Q4U0X6, POL_HTL3P  ;  P03363, POL_HTLV2  ;  O93215, POL_HV190  ;
DR   O12158, POL_HV192  ;  O89290, POL_HV193  ;  Q9QBY3, POL_HV196  ;
DR   Q9QBZ9, POL_HV197  ;  O41798, POL_HV19N  ;  P03369, POL_HV1A2  ;
DR   Q77373, POL_HV1AN  ;  P03366, POL_HV1B1  ;  P04587, POL_HV1B5  ;
DR   Q73368, POL_HV1B9  ;  P03367, POL_HV1BR  ;  P04589, POL_HV1EL  ;
DR   Q75002, POL_HV1ET  ;  P04585, POL_HV1H2  ;  P20875, POL_HV1JR  ;
DR   P0C6F2, POL_HV1LW  ;  Q9QBZ1, POL_HV1M2  ;  P04588, POL_HV1MA  ;
DR   P05961, POL_HV1MN  ;  Q9QBZ5, POL_HV1MP  ;  Q79666, POL_HV1MV  ;
DR   P12497, POL_HV1N5  ;  P18802, POL_HV1ND  ;  P20892, POL_HV1OY  ;
DR   P05959, POL_HV1RH  ;  Q9WC54, POL_HV1S2  ;  Q9WC63, POL_HV1S9  ;
DR   O89940, POL_HV1SE  ;  P24740, POL_HV1U4  ;  Q9Q720, POL_HV1V9  ;
DR   Q9QSR3, POL_HV1VI  ;  P35963, POL_HV1Y2  ;  Q9IDV9, POL_HV1YB  ;
DR   O91080, POL_HV1YF  ;  P12499, POL_HV1Z2  ;  P18096, POL_HV2BE  ;
DR   P24107, POL_HV2CA  ;  P17757, POL_HV2D1  ;  P15833, POL_HV2D2  ;
DR   Q89928, POL_HV2EH  ;  P18042, POL_HV2G1  ;  Q74120, POL_HV2KR  ;
DR   P05962, POL_HV2NZ  ;  P04584, POL_HV2RO  ;  P12451, POL_HV2SB  ;
DR   P20876, POL_HV2ST  ;  Q76634, POL_HV2UC  ;  P04026, POL_IPHA   ;
DR   P11368, POL_IPMA   ;  P12894, POL_IPMAI  ;  Q82851, POL_JEMBR  ;
DR   P31623, POL_JSRV   ;  Q9TTC1, POL_KORV   ;  P03356, POL_MLVAV  ;
DR   P26810, POL_MLVF5  ;  P26809, POL_MLVFF  ;  P26808, POL_MLVFP  ;
DR   P03355, POL_MLVMS  ;  P11227, POL_MLVRD  ;  P31795, POL_MLVRK  ;
DR   P03365, POL_MMTVB  ;  P11283, POL_MMTVC  ;  P07572, POL_MPMV   ;
DR   P16901, POL_OMVVS  ;  P03358, POL_RSFFV  ;  P03354, POL_RSVP   ;
DR   Q04095, POL_RSVSA  ;  O92956, POL_RSVSB  ;  P27502, POL_RTBVP  ;
DR   P23074, POL_SFV1   ;  P27401, POL_SFV3L  ;  Q87040, POL_SFVCP  ;
DR   P17283, POL_SIVCZ  ;  Q1A249, POL_SIVEK  ;  Q02836, POL_SIVG1  ;
DR   P22382, POL_SIVGB  ;  P05896, POL_SIVM1  ;  Q1A267, POL_SIVMB  ;
DR   P05897, POL_SIVMK  ;  P12502, POL_SIVS4  ;  P19505, POL_SIVSP  ;
DR   Q8AII1, POL_SIVTN  ;  P27973, POL_SIVV1  ;  P12500, POL_SIVV2  ;
DR   P12501, POL_SIVV3  ;  P27980, POL_SIVVG  ;  P05895, POL_SIVVT  ;
DR   P03364, POL_SMRVH  ;  P15629, POL_SOCMV  ;  P04025, POL_SRV1   ;
DR   P51517, POL_SRV2   ;  P03370, POL_VILV   ;  P23426, POL_VILV1  ;
DR   P23427, POL_VILV2  ;  P35956, POL_VILVK  ;  O92815, POL_WDSV   ;
DR   P03359, POL_WMSV   ;  Q2F7J3, POL_XMRV3  ;  Q2F7J0, POL_XMRV4  ;
DR   A1Z651, POL_XMRV6  ;  P19593, RDPO_SCEOB ;  P23072, RT16_MYXXA ;
DR   P23071, RT65_MYXXA ;  P21325, RT67_ECOLX ;  P23070, RT86_ECOLX ;
DR   Q95SX7, RTBS_DROME ;  P21329, RTJK_DROFU ;  P21328, RTJK_DROME ;
DR   Q9NBX4, RTXE_DROME ;  Q94818, TE80_TETTH ;  Q94819, TE95_TETTH ;
DR   Q9SPU7, TERT_ARATH ;  Q27ID4, TERT_BOVIN ;  Q6A548, TERT_CANFA ;
DR   O00939, TERT_EUPAE ;  O14746, TERT_HUMAN ;  O70372, TERT_MOUSE ;
DR   Q8LKW0, TERT_ORYSJ ;  O76332, TERT_OXYTR ;  Q673L6, TERT_RAT   ;
DR   O13339, TERT_SCHPO ;  O77448, TERT_TETTH ;  Q06163, TERT_YEAST ;
DR   Q07163, TY1AB_YEASX;  O13527, YA11B_YEAST;  Q12490, YB11B_YEAST;
DR   Q12193, YB12B_YEAST;  Q12491, YB21B_YEAST;  P25384, YC21B_YEAST;
DR   Q03855, YD11B_YEAST;  Q99231, YD12B_YEAST;  Q07793, YD13B_YEAST;
DR   P0C2I2, YD14B_YEAST;  P0C2I3, YD15B_YEAST;  Q12472, YD21B_YEAST;
DR   Q03494, YD22B_YEAST;  Q07791, YD23B_YEAST;  Q03612, YE11B_YEAST;
DR   Q03619, YE12B_YEAST;  P0CX63, YF21B_YEAST;  Q12141, YG11B_YEAST;
DR   Q12269, YG12B_YEAST;  Q12316, YG13B_YEAST;  Q12337, YG21B_YEAST;
DR   P0CX64, YG22B_YEAST;  Q99315, YG31B_YEAST;  O13535, YH11B_YEAST;
DR   Q7LHG5, YI31B_YEAST;  P47098, YJ11B_YEAST;  P47100, YJ12B_YEAST;
DR   Q12088, YL11B_YEAST;  P0C2I5, YL12B_YEAST;  P0C2I6, YL13B_YEAST;
DR   P0C2I7, YL14B_YEAST;  P0C2J3, YL21B_YEAST;  P0C2J5, YL22B_YEAST;
DR   Q04711, YM11B_YEAST;  Q03434, YM12B_YEAST;  Q04214, YM13B_YEAST;
DR   Q04670, YM14B_YEAST;  Q12112, YN11B_YEAST;  Q99337, YN12B_YEAST;
DR   Q12273, YO11B_YEAST;  Q92393, YO12B_YEAST;  Q12113, YO21B_YEAST;
DR   Q12501, YO22B_YEAST;  Q12414, YP11B_YEAST;  P0C2I9, YP12B_YEAST;
DR   P0C2J0, YP13B_YEAST;  P0C2J1, YP14B_YEAST;
//
ID   2.7.7.50
DE   mRNA guanylyltransferase.
AN   GTP--RNA guanylyltransferase.
AN   mRNA capping enzyme.
CA   GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA.
CC   -!- Can modify also synthetic poly(A) and poly(G) to form the structures
CC       m(7)G(5')pppAn and m(7)G(5')pppGn.
DR   P11079, LMBD2_REOVD;  Q91RA4, LMBD2_REOVJ;  Q91RA6, LMBD2_REOVL;
DR   Q755D0, MCE1_ASHGO ;  Q17607, MCE1_CAEEL ;  P78587, MCE1_CANAL ;
DR   Q6FQ31, MCE1_CANGA ;  Q6NY98, MCE1_DANRE ;  Q6BT58, MCE1_DEBHA ;
DR   O60942, MCE1_HUMAN ;  Q6CWR0, MCE1_KLULA ;  O55236, MCE1_MOUSE ;
DR   Q7SB53, MCE1_NEUCR ;  P40997, MCE1_SCHPO ;  Q6C783, MCE1_YARLI ;
DR   Q01159, MCE1_YEAST ;  Q8V2R8, MCEL_CAMPM ;  Q775U0, MCEL_CAMPS ;
DR   Q8QMV9, MCEL_CWPXB ;  Q80DX6, MCEL_CWPXG ;  Q9J584, MCEL_FOWPN ;
DR   P25950, MCEL_RFVKA ;  O57209, MCEL_VACCA ;  P20979, MCEL_VACCC ;
DR   Q9JFA8, MCEL_VACCT ;  P04298, MCEL_VACCW ;  P33057, MCEL_VAR67 ;
DR   P32094, MCE_ASFB7  ;  P0C995, MCE_ASFK5  ;  Q65216, MCE_ASFM2  ;
DR   P0C993, MCE_ASFP4  ;  P0C994, MCE_ASFWA  ;  Q5UQX1, MCE_MIMIV  ;
DR   Q84424, MCE_PBCV1  ;  P14583, MCE_RDVA   ;  Q85437, MCE_RDVF   ;
DR   Q1WNZ7, MCE_RGDV   ;  P12366, MCE_WTV    ;  Q8VA43, VP1_AQRVA  ;
DR   Q8JU62, VP1_AQRVC  ;  B2BND9, VP1_AQRVG  ;  O56043, VP2_RRSVT  ;
DR   Q9INI4, VP3_BAVJK  ;  Q7TDB4, VP3_MYRV9  ;  Q3ZK57, VP3_ROT41  ;
DR   B1NKR5, VP3_ROTAD  ;  A9Q1K9, VP3_ROTB2  ;  A7J3A0, VP3_ROTBN  ;
DR   Q65526, VP3_ROTBS  ;  Q6WAT6, VP3_ROTBU  ;  Q6WNV6, VP3_ROTCC  ;
DR   Q6WNV7, VP3_ROTEL  ;  A4ZCW6, VP3_ROTH3  ;  Q6WNW3, VP3_ROTH6  ;
DR   B1NKR1, VP3_ROTH7  ;  Q82041, VP3_ROTHC  ;  Q6WNW5, VP3_ROTHD  ;
DR   Q9QNB1, VP3_ROTHK  ;  B1NKS7, VP3_ROTHL  ;  B1NKT1, VP3_ROTHP  ;
DR   A7J392, VP3_ROTHS  ;  B1NKT9, VP3_ROTHT  ;  Q91HJ9, VP3_ROTHU  ;
DR   Q6WVH5, VP3_ROTHW  ;  Q45UF7, VP3_ROTJ1  ;  Q6WNV8, VP3_ROTP5  ;
DR   P26192, VP3_ROTPC  ;  Q8BB04, VP3_ROTRF  ;  P15736, VP3_ROTS1  ;
DR   A2T3S5, VP3_ROTSH  ;  B3F2X7, VP3_ROTTU  ;  B2BMF9, VP3_ROTW3  ;
DR   B1NKU3, VP3_ROTWI  ;  A7J3A4, VP3_ROTYO  ;  Q91ID8, VP4_LDCPR  ;
DR   Q2Y0E6, VP5_APRVF  ;
//
ID   2.7.7.51
DE   Adenylylsulfate--ammonia adenylyltransferase.
CA   Adenylyl sulfate + NH(3) = adenosine 5'-phosphoramidate + sulfate.
//
ID   2.7.7.52
DE   RNA uridylyltransferase.
AN   Terminal uridylyltransferase.
AN   TUT.
CA   UTP + RNA(n) = diphosphate + RNA(n+1).
CC   -!- Requires an oligoribonucleotide or polyribonucleotide with a free
CC       terminal 3'-OH as a primer.
DR   D2HS90, STPAP_AILME;  Q1JPD6, STPAP_BOVIN;  Q4KMD7, STPAP_DANRE;
DR   Q9H6E5, STPAP_HUMAN;  Q8R3F9, STPAP_MOUSE;  Q3MHT4, STPAP_RAT  ;
DR   A9JTS5, STPAP_XENTR;  Q5TAX3, TUT4_HUMAN ;  B2RX14, TUT4_MOUSE ;
DR   Q5VYS8, TUT7_HUMAN ;  Q5BLK4, TUT7_MOUSE ;
//
ID   2.7.7.53
DE   ATP adenylyltransferase.
AN   AP-4-A phosphorylase.
AN   Bis(5'-nucleosyl)-tetraphosphate phosphorylase (NDP-forming).
AN   Diadenosine 5',5'''-P(1),P(4)-tetraphosphate phosphorylase.
AN   Diadenosinetetraphosphate alpha-beta-phosphorylase.
CA   ADP + ATP = phosphate + P(1),P(4)-bis(5'-adenosyl) tetraphosphate.
CC   -!- GTP and adenosine tetraphosphate can also act as adenylyl acceptors.
DR   O06201, AP4A_MYCTU ;  P16550, APA1_YEAST ;  P49348, APA2_KLULA ;
DR   P22108, APA2_YEAST ;
//
ID   2.7.7.54
DE   Phenylalanine adenylyltransferase.
CA   ATP + L-phenylalanine = diphosphate + N-adenylyl-L-phenylalanine.
CC   -!- Part of the system for biosynthesis of the alkaloid cyclopeptine in
CC       Penicillium cyclopium.
//
ID   2.7.7.55
DE   Anthranilate adenylyltransferase.
AN   Anthranilic acid adenylyltransferase.
CA   ATP + anthranilate = diphosphate + N-adenylylanthranilate.
CC   -!- Part of the system for biosynthesis of the alkaloid cyclopeptine in
CC       Penicillium cyclopium.
//
ID   2.7.7.56
DE   tRNA nucleotidyltransferase.
AN   Phosphate-dependent exonuclease.
AN   Ribonuclease PH.
AN   RNase PH.
CA   tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate.
CC   -!- Brings about the final exonucleolytic trimming of the 3'-terminus of
CC       tRNA precursors in Escherichia coli by a phosphorolysis, producing a
CC       mature 3'-terminus in tRNA and nucleoside diphosphate.
CC   -!- Not identical with EC 2.7.7.8.
PR   PROSITE; PDOC00983;
DR   B0CAB9, RNPH_ACAM1 ;  Q6FFX5, RNPH_ACIAD ;  B7H2J6, RNPH_ACIB3 ;
DR   B7IBN8, RNPH_ACIB5 ;  B2I029, RNPH_ACIBC ;  B0VMP4, RNPH_ACIBS ;
DR   A3M0U3, RNPH_ACIBT ;  B0V5W8, RNPH_ACIBY ;  A3MYC7, RNPH_ACTP2 ;
DR   B3GZP5, RNPH_ACTP7 ;  B0BRL3, RNPH_ACTPJ ;  A6VLF1, RNPH_ACTSZ ;
DR   B9J7T9, RNPH_AGRRK ;  Q8UIG8, RNPH_AGRT5 ;  B9JZG3, RNPH_AGRVS ;
DR   Q0VT66, RNPH_ALCBS ;  Q0A5V1, RNPH_ALHEH ;  B6EPI9, RNPH_ALISL ;
DR   B4S201, RNPH_ALTMD ;  B8J5H5, RNPH_ANAD2 ;  Q2IEX1, RNPH_ANADE ;
DR   A7HFW3, RNPH_ANADF ;  B4UBI2, RNPH_ANASK ;  B9MQJ8, RNPH_ANATD ;
DR   Q3M9Q2, RNPH_ANAVT ;  B7GH12, RNPH_ANOFW ;  O67069, RNPH_AQUAE ;
DR   Q5P5J6, RNPH_AROAE ;  A8HV93, RNPH_AZOC5 ;  A1KCM3, RNPH_AZOSB ;
DR   C1DI48, RNPH_AZOVD ;  A7Z7C6, RNPH_BACA2 ;  C3PA74, RNPH_BACAA ;
DR   C3L7T5, RNPH_BACAC ;  Q81LA9, RNPH_BACAN ;  B7JQ74, RNPH_BACC0 ;
DR   Q72ZT1, RNPH_BACC1 ;  B7IIZ1, RNPH_BACC2 ;  C1ETS9, RNPH_BACC3 ;
DR   B7HEB3, RNPH_BACC4 ;  B7HQP4, RNPH_BACC7 ;  A7GTG6, RNPH_BACCN ;
DR   B9IZ73, RNPH_BACCQ ;  Q817P3, RNPH_BACCR ;  Q633V4, RNPH_BACCZ ;
DR   Q9K8D8, RNPH_BACHD ;  Q6HD42, RNPH_BACHK ;  Q65GG2, RNPH_BACLD ;
DR   A8FFY6, RNPH_BACP2 ;  Q5WEM3, RNPH_BACSK ;  P28619, RNPH_BACSU ;
DR   A9VIV4, RNPH_BACWK ;  Q6MJR9, RNPH_BDEBA ;  B2IH14, RNPH_BEII9 ;
DR   Q8G7I0, RNPH_BIFLO ;  Q7WI90, RNPH_BORBR ;  Q7W6C1, RNPH_BORPA ;
DR   Q7VXY3, RNPH_BORPE ;  Q89WK4, RNPH_BRAJA ;  A5E8I9, RNPH_BRASB ;
DR   A4YJR3, RNPH_BRASO ;  C0ZAF8, RNPH_BREBN ;  B2S8G4, RNPH_BRUA1 ;
DR   Q2YP33, RNPH_BRUA2 ;  Q57FK3, RNPH_BRUAB ;  A9M7B8, RNPH_BRUC2 ;
DR   C0RGM7, RNPH_BRUMB ;  Q8YEV2, RNPH_BRUME ;  A5VNA8, RNPH_BRUO2 ;
DR   B0CJ32, RNPH_BRUSI ;  Q8G2Y5, RNPH_BRUSU ;  B1YUN3, RNPH_BURA4 ;
DR   Q1BY75, RNPH_BURCA ;  B1JXM2, RNPH_BURCC ;  A0K5H3, RNPH_BURCH ;
DR   B4EBP8, RNPH_BURCJ ;  Q0BHF7, RNPH_BURCM ;  A9AEQ7, RNPH_BURM1 ;
DR   A3MML4, RNPH_BURM7 ;  A2S9I2, RNPH_BURM9 ;  Q62HZ8, RNPH_BURMA ;
DR   A3NY37, RNPH_BURP0 ;  A3NC95, RNPH_BURP6 ;  B2JEI0, RNPH_BURP8 ;
DR   B2T6B5, RNPH_BURPP ;  Q63RV5, RNPH_BURPS ;  Q39IL4, RNPH_BURS3 ;
DR   Q2SY74, RNPH_BURTA ;  A4JCC2, RNPH_BURVG ;  Q13V47, RNPH_BURXL ;
DR   A4XI64, RNPH_CALS8 ;  Q3AFA0, RNPH_CARHZ ;  B8GXP2, RNPH_CAUCN ;
DR   P0CAW5, RNPH_CAUCR ;  B0T369, RNPH_CAUSK ;  B3PGE8, RNPH_CELJU ;
DR   Q7MBD4, RNPH_CHRVO ;  A8ARN1, RNPH_CITK8 ;  B2UZ31, RNPH_CLOBA ;
DR   B2TJ05, RNPH_CLOBB ;  B8I1A8, RNPH_CLOCE ;  B9DWL2, RNPH_CLOK1 ;
DR   A5N2V9, RNPH_CLOK5 ;  Q0TN64, RNPH_CLOP1 ;  Q8XI67, RNPH_CLOPE ;
DR   Q0SQU1, RNPH_CLOPS ;  Q48AN3, RNPH_COLP3 ;  Q6NFN6, RNPH_CORDI ;
DR   Q8FMU8, RNPH_COREF ;  A4QGQ6, RNPH_CORGB ;  Q8NMR4, RNPH_CORGL ;
DR   C4LJY5, RNPH_CORK4 ;  A9KGR9, RNPH_COXBN ;  A9NB33, RNPH_COXBR ;
DR   Q83EL9, RNPH_COXBU ;  Q0KD27, RNPH_CUPNH ;  B3R3N0, RNPH_CUPTR ;
DR   B1WUL8, RNPH_CYAA5 ;  B8HPC6, RNPH_CYAP4 ;  B7KB81, RNPH_CYAP7 ;
DR   Q479A2, RNPH_DECAR ;  Q3Z6Z8, RNPH_DEHE1 ;  A5FQ49, RNPH_DEHSB ;
DR   Q3ZYH8, RNPH_DEHSC ;  Q9RU11, RNPH_DEIRA ;  B1I4W9, RNPH_DESAP ;
DR   Q6ANS2, RNPH_DESPS ;  A4J7Y7, RNPH_DESRM ;  A5EV74, RNPH_DICNV ;
DR   B5YEU4, RNPH_DICT6 ;  B8E0G7, RNPH_DICTD ;  A8LPD1, RNPH_DINSH ;
DR   A7ZTJ4, RNPH_ECO24 ;  B7UM50, RNPH_ECO27 ;  P66680, RNPH_ECO57 ;
DR   B5YWE1, RNPH_ECO5E ;  P0CG18, RNPH_ECOBW ;  A8A6A5, RNPH_ECOHS ;
DR   A1AHH4, RNPH_ECOK1 ;  Q0TBG6, RNPH_ECOL5 ;  P66679, RNPH_ECOL6 ;
DR   B1IYV7, RNPH_ECOLC ;  P0CG19, RNPH_ECOLI ;  B6I3M0, RNPH_ECOSE ;
DR   B1LK80, RNPH_ECOSM ;  C5B9C9, RNPH_EDWI9 ;  A4W506, RNPH_ENT38 ;
DR   Q6DAW2, RNPH_ERWCT ;  B2VF76, RNPH_ERWT9 ;  Q2NAJ7, RNPH_ERYLH ;
DR   B1YJW6, RNPH_EXIS2 ;  B0U040, RNPH_FRAP2 ;  Q2JEN8, RNPH_FRASC ;
DR   A8L766, RNPH_FRASN ;  Q14HY4, RNPH_FRAT1 ;  A7NA52, RNPH_FRATF ;
DR   Q2A562, RNPH_FRATH ;  B2SF43, RNPH_FRATM ;  A0Q4X5, RNPH_FRATN ;
DR   Q0BNH8, RNPH_FRATO ;  Q5NGI2, RNPH_FRATT ;  A4IYU1, RNPH_FRATW ;
DR   Q5KWI5, RNPH_GEOKA ;  B3E3D2, RNPH_GEOLS ;  Q39UG9, RNPH_GEOMG ;
DR   B9M3E3, RNPH_GEOSF ;  Q74C79, RNPH_GEOSL ;  C5D5M7, RNPH_GEOSW ;
DR   A4IRI5, RNPH_GEOTN ;  A5G3S1, RNPH_GEOUR ;  Q7VP10, RNPH_HAEDU ;
DR   Q4QNR6, RNPH_HAEI8 ;  A5UAL6, RNPH_HAEIE ;  A5UG91, RNPH_HAEIG ;
DR   P44444, RNPH_HAEIN ;  B8F6D8, RNPH_HAEPS ;  Q0I4U1, RNPH_HAES1 ;
DR   B0UWM2, RNPH_HAES2 ;  Q2S8P0, RNPH_HAHCH ;  A1WVN7, RNPH_HALHL ;
DR   C4K3X0, RNPH_HAMD5 ;  B4U8T3, RNPH_HYDS0 ;  Q5QYL5, RNPH_IDILO ;
DR   B5XTF9, RNPH_KLEP3 ;  A6TFN5, RNPH_KLEP7 ;  C1DCK5, RNPH_LARHH ;
DR   Q5X3P0, RNPH_LEGPA ;  A5IDJ5, RNPH_LEGPC ;  Q5ZTZ6, RNPH_LEGPH ;
DR   Q5WV28, RNPH_LEGPL ;  Q9X528, RNPH_LEGPN ;  Q6AEK9, RNPH_LEIXX ;
DR   Q92CH1, RNPH_LISIN ;  C1L2E3, RNPH_LISMC ;  Q720J1, RNPH_LISMF ;
DR   B8DHZ4, RNPH_LISMH ;  Q8Y7N6, RNPH_LISMO ;  A0AHX9, RNPH_LISW6 ;
DR   Q65W01, RNPH_MANSM ;  A1TY30, RNPH_MARAV ;  Q0AKA6, RNPH_MARMM ;
DR   A6W3H7, RNPH_MARMS ;  Q11B42, RNPH_MESSB ;  B7L092, RNPH_METC4 ;
DR   Q602N9, RNPH_METCA ;  A9VZR7, RNPH_METEP ;  Q1GXA4, RNPH_METFK ;
DR   B8IFR7, RNPH_METNO ;  B1ZJ73, RNPH_METPB ;  B1M4N1, RNPH_METRJ ;
DR   B0UP55, RNPH_METS4 ;  B8ERN7, RNPH_METSB ;  Q2RL40, RNPH_MOOTA ;
DR   A0QD04, RNPH_MYCA1 ;  B1MLZ3, RNPH_MYCA9 ;  Q7U076, RNPH_MYCBO ;
DR   A1KID0, RNPH_MYCBP ;  C1AMY5, RNPH_MYCBT ;  A4T8F7, RNPH_MYCGI ;
DR   B8ZR59, RNPH_MYCLB ;  P37939, RNPH_MYCLE ;  Q73X87, RNPH_MYCPA ;
DR   A0R1W8, RNPH_MYCS2 ;  A3Q379, RNPH_MYCSJ ;  A1UJV2, RNPH_MYCSK ;
DR   Q1B585, RNPH_MYCSS ;  A5U240, RNPH_MYCTA ;  Q10628, RNPH_MYCTU ;
DR   A0PUG0, RNPH_MYCUA ;  A1TD14, RNPH_MYCVP ;  Q1DAT4, RNPH_MYXXD ;
DR   Q5F840, RNPH_NEIG1 ;  B4RL28, RNPH_NEIG2 ;  A9M0T5, RNPH_NEIM0 ;
DR   Q9JTN2, RNPH_NEIMA ;  Q9JYN5, RNPH_NEIMB ;  A1KUT9, RNPH_NEIMF ;
DR   Q0AJ79, RNPH_NITEC ;  Q82XJ4, RNPH_NITEU ;  Q1QRU5, RNPH_NITHX ;
DR   Q2YCZ6, RNPH_NITMU ;  Q3J8F0, RNPH_NITOC ;  Q3SW80, RNPH_NITWN ;
DR   Q5Z0V1, RNPH_NOCFA ;  A1SGA2, RNPH_NOCSJ ;  B2J9Q1, RNPH_NOSP7 ;
DR   Q8Z0M2, RNPH_NOSS1 ;  Q8EPJ5, RNPH_OCEIH ;  A6WVA9, RNPH_OCHA4 ;
DR   B6JCH9, RNPH_OLICO ;  A7HZ45, RNPH_PARL1 ;  Q9AES0, RNPH_PASHA ;
DR   Q9CJW5, RNPH_PASMU ;  C6DIC7, RNPH_PECCP ;  C0QTN9, RNPH_PERMH ;
DR   B4RC87, RNPH_PHEZH ;  Q7MAX2, RNPH_PHOLL ;  Q6LVN8, RNPH_PHOPR ;
DR   Q6A759, RNPH_PROAC ;  B4F0W3, RNPH_PROMH ;  Q7V4V8, RNPH_PROMM ;
DR   Q15MV7, RNPH_PSEA6 ;  A6VEE1, RNPH_PSEA7 ;  B7V5M5, RNPH_PSEA8 ;
DR   Q02E28, RNPH_PSEAB ;  P50597, RNPH_PSEAE ;  Q4K3R6, RNPH_PSEF5 ;
DR   C3K479, RNPH_PSEFS ;  Q3IJI0, RNPH_PSEHT ;  A4Y0L7, RNPH_PSEMY ;
DR   A5WB10, RNPH_PSEP1 ;  Q3K4M0, RNPH_PSEPF ;  B0KQ94, RNPH_PSEPG ;
DR   Q88C89, RNPH_PSEPK ;  B1J4L4, RNPH_PSEPW ;  Q88BE0, RNPH_PSESM ;
DR   Q4ZZY6, RNPH_PSEU2 ;  A4VGR8, RNPH_PSEU5 ;  Q4FQJ5, RNPH_PSYA2 ;
DR   Q1Q8S2, RNPH_PSYCK ;  A1T097, RNPH_PSYIN ;  A5WHJ0, RNPH_PSYWF ;
DR   Q1LQ38, RNPH_RALME ;  B2U8D8, RNPH_RALPJ ;  Q8XXF5, RNPH_RALSO ;
DR   B3PZA2, RNPH_RHIE6 ;  Q2KDA1, RNPH_RHIEC ;  Q1MMD1, RNPH_RHIL3 ;
DR   Q98DN6, RNPH_RHILO ;  B5ZMW8, RNPH_RHILW ;  Q92SK2, RNPH_RHIME ;
DR   C3MEJ1, RNPH_RHISN ;  Q7URE2, RNPH_RHOBA ;  C1A1V2, RNPH_RHOE4 ;
DR   Q2J324, RNPH_RHOP2 ;  Q6NCY8, RNPH_RHOPA ;  Q21CI6, RNPH_RHOPB ;
DR   Q13E56, RNPH_RHOPS ;  B3Q968, RNPH_RHOPT ;  Q2RN60, RNPH_RHORT ;
DR   A3PNR8, RNPH_RHOS1 ;  A4WVY1, RNPH_RHOS5 ;  B9KPU4, RNPH_RHOSK ;
DR   C3PP75, RNPH_RICAE ;  A8GPB9, RNPH_RICAH ;  A8GW25, RNPH_RICB8 ;
DR   Q1RIX6, RNPH_RICBR ;  A8EY33, RNPH_RICCK ;  Q92GZ7, RNPH_RICCN ;
DR   Q4UJN4, RNPH_RICFE ;  Q9ZCT5, RNPH_RICPR ;  C4K2U2, RNPH_RICPU ;
DR   B0BUM3, RNPH_RICRO ;  A8GT33, RNPH_RICRS ;  Q16D02, RNPH_ROSDO ;
DR   Q21EE1, RNPH_SACD2 ;  A4F913, RNPH_SACEN ;  B5EXE7, RNPH_SALA4 ;
DR   A8M4I1, RNPH_SALAI ;  A9MKN2, RNPH_SALAR ;  Q57I99, RNPH_SALCH ;
DR   B5FM66, RNPH_SALDC ;  B5R5G7, RNPH_SALEP ;  B5RG80, RNPH_SALG2 ;
DR   B4T9Y6, RNPH_SALHS ;  B4SXE4, RNPH_SALNS ;  Q5PC25, RNPH_SALPA ;
DR   B5BI17, RNPH_SALPK ;  B4TZY4, RNPH_SALSV ;  P0A2C4, RNPH_SALTI ;
DR   A4X3X5, RNPH_SALTO ;  P0A2C3, RNPH_SALTY ;  A8GLF0, RNPH_SERP5 ;
DR   A1S2C5, RNPH_SHEAM ;  B8E4I8, RNPH_SHEB2 ;  A3CZI9, RNPH_SHEB5 ;
DR   A6WI99, RNPH_SHEB8 ;  A9KXZ7, RNPH_SHEB9 ;  Q12SG2, RNPH_SHEDO ;
DR   Q07WF3, RNPH_SHEFN ;  B0TQK4, RNPH_SHEHH ;  A3QIQ6, RNPH_SHELP ;
DR   Q8E9L4, RNPH_SHEON ;  A8H9B7, RNPH_SHEPA ;  A4Y2K5, RNPH_SHEPC ;
DR   B8CM22, RNPH_SHEPW ;  A0L1S6, RNPH_SHESA ;  A8FQ68, RNPH_SHESH ;
DR   Q0HE49, RNPH_SHESM ;  Q0HZV0, RNPH_SHESR ;  A1RET8, RNPH_SHESW ;
DR   B1KL12, RNPH_SHEWM ;  B2TTV7, RNPH_SHIB3 ;  Q31UY3, RNPH_SHIBS ;
DR   Q329L3, RNPH_SHIDS ;  Q0SYH0, RNPH_SHIF8 ;  Q83PN2, RNPH_SHIFL ;
DR   Q3YW05, RNPH_SHISS ;  Q5LWF6, RNPH_SILPO ;  Q1GCL2, RNPH_SILST ;
DR   A6U5E0, RNPH_SINMW ;  Q2NQT7, RNPH_SODGM ;  Q01NZ9, RNPH_SOLUE ;
DR   Q1GWJ5, RNPH_SPHAL ;  A5V3R9, RNPH_SPHWW ;  Q82D17, RNPH_STRAW ;
DR   Q9S2H7, RNPH_STRCO ;  B1VVV6, RNPH_STRGG ;  B4SU06, RNPH_STRM5 ;
DR   B2FT17, RNPH_STRMK ;  B2V890, RNPH_SULSY ;  Q67SL5, RNPH_SYMTH ;
DR   Q2LTS3, RNPH_SYNAS ;  Q31PB6, RNPH_SYNE7 ;  Q2JRJ9, RNPH_SYNJA ;
DR   Q2JKT3, RNPH_SYNJB ;  Q5N4V3, RNPH_SYNP6 ;  Q7U9I1, RNPH_SYNPX ;
DR   Q3AMY6, RNPH_SYNSC ;  Q0AZR6, RNPH_SYNWW ;  C5BLF9, RNPH_TERTT ;
DR   Q8DLA4, RNPH_THEEB ;  B0KBM5, RNPH_THEP3 ;  B0K3T4, RNPH_THEPX ;
DR   Q8RC30, RNPH_THETN ;  B5YFY8, RNPH_THEYD ;  B8GPB2, RNPH_THISH ;
DR   C4L818, RNPH_TOLAT ;  Q83HF6, RNPH_TROW8 ;  Q83FT1, RNPH_TROWT ;
DR   Q9KVD6, RNPH_VIBCH ;  Q5E8P0, RNPH_VIBF1 ;  B5FFE2, RNPH_VIBFM ;
DR   Q87T93, RNPH_VIBPA ;  B7VHJ7, RNPH_VIBSL ;  Q8DDX4, RNPH_VIBVU ;
DR   Q7MPT3, RNPH_VIBVY ;  Q8PH63, RNPH_XANAC ;  Q3BPR8, RNPH_XANC5 ;
DR   Q4UY39, RNPH_XANC8 ;  B0RP96, RNPH_XANCB ;  Q8P5T5, RNPH_XANCP ;
DR   Q2P6N2, RNPH_XANOM ;  B2SLL1, RNPH_XANOP ;  A7IID4, RNPH_XANP2 ;
DR   B2IA38, RNPH_XYLF2 ;  Q9PD74, RNPH_XYLFA ;  B0U6W7, RNPH_XYLFM ;
DR   Q87DG3, RNPH_XYLFT ;  A1JHW7, RNPH_YERE8 ;  A7FCS9, RNPH_YERP3 ;
DR   Q1C262, RNPH_YERPA ;  B2JYM8, RNPH_YERPB ;  Q8ZJP8, RNPH_YERPE ;
DR   A9R668, RNPH_YERPG ;  Q1CCZ7, RNPH_YERPN ;  A4TSE2, RNPH_YERPP ;
DR   Q66GE1, RNPH_YERPS ;  B1JQX8, RNPH_YERPY ;  Q5NRL6, RNPH_ZYMMO ;
//
ID   2.7.7.57
DE   N-methylphosphoethanolamine cytidylyltransferase.
CA   CTP + N-methylethanolamine phosphate = diphosphate + CDP-N-
CA   methylethanolamine.
//
ID   2.7.7.58
DE   (2,3-dihydroxybenzoyl)adenylate synthase.
AN   2,3-dihydroxybenzoate-AMP ligase.
CA   ATP + 2,3-dihydroxybenzoate = diphosphate + (2,3-
CA   dihydroxybenzoyl)adenylate.
DR   Q8XBV3, ENTE_ECO57 ;  P10378, ENTE_ECOLI ;
//
ID   2.7.7.59
DE   [Protein-PII] uridylyltransferase.
AN   PII uridylyl-transferase.
AN   Uridylyl removing enzyme.
CA   UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII].
CC   -!- The enzyme uridylylates and de-uridylylates the small trimeric
CC       protein PII.
DR   Q6FAM5, GLND_ACIAD ;  B7H3W7, GLND_ACIB3 ;  B7I420, GLND_ACIB5 ;
DR   B2HYT7, GLND_ACIBC ;  B0VR80, GLND_ACIBS ;  A3M4Q8, GLND_ACIBT ;
DR   B0VC63, GLND_ACIBY ;  Q8UIF1, GLND_AGRT5 ;  B9JZI2, GLND_AGRVS ;
DR   Q5NZH8, GLND_AROAE ;  Q8RQD1, GLND_AZOBR ;  C1DSU8, GLND_AZOVD ;
DR   P36223, GLND_AZOVI ;  Q2L165, GLND_BORA1 ;  Q7WJ96, GLND_BORBR ;
DR   Q7WA62, GLND_BORPA ;  Q7VYD2, GLND_BORPE ;  Q89VX9, GLND_BRAJA ;
DR   A5ETJ9, GLND_BRASB ;  A4YKP3, GLND_BRASO ;  B2S8D8, GLND_BRUA1 ;
DR   Q2YNZ1, GLND_BRUA2 ;  Q57FN0, GLND_BRUAB ;  C0RGK0, GLND_BRUMB ;
DR   Q8YES3, GLND_BRUME ;  A5VN81, GLND_BRUO2 ;  B0CIQ3, GLND_BRUSI ;
DR   Q8G312, GLND_BRUSU ;  B1YS76, GLND_BURA4 ;  Q1BHI4, GLND_BURCA ;
DR   B1JUF2, GLND_BURCC ;  A3MKU6, GLND_BURM7 ;  A2SB69, GLND_BURM9 ;
DR   Q62JC2, GLND_BURMA ;  A1V572, GLND_BURMS ;  A3NWN4, GLND_BURP0 ;
DR   Q3JR26, GLND_BURP1 ;  A3NAV0, GLND_BURP6 ;  Q63T10, GLND_BURPS ;
DR   Q39F41, GLND_BURS3 ;  Q2SX00, GLND_BURTA ;  A4JF78, GLND_BURVG ;
DR   B8GWX0, GLND_CAUCN ;  Q9AC53, GLND_CAUCR ;  Q7NTY6, GLND_CHRVO ;
DR   A8ALC3, GLND_CITK8 ;  Q485H4, GLND_COLP3 ;  Q9X706, GLND_CORGL ;
DR   Q470D5, GLND_CUPPJ ;  Q47F95, GLND_DECAR ;  A7ZHQ7, GLND_ECO24 ;
DR   B7UIL2, GLND_ECO27 ;  B7MBE8, GLND_ECO45 ;  B7LGM7, GLND_ECO55 ;
DR   Q8X8Y6, GLND_ECO57 ;  B5Z0E5, GLND_ECO5E ;  B7NIC8, GLND_ECO7I ;
DR   B7MP27, GLND_ECO81 ;  B7M1A6, GLND_ECO8A ;  C4ZRQ9, GLND_ECOBW ;
DR   B1XD36, GLND_ECODH ;  A7ZWB3, GLND_ECOHS ;  A1A7L1, GLND_ECOK1 ;
DR   Q0TLG6, GLND_ECOL5 ;  Q8CY19, GLND_ECOL6 ;  B1IQH4, GLND_ECOLC ;
DR   P27249, GLND_ECOLI ;  B7N834, GLND_ECOLU ;  B6HZE1, GLND_ECOSE ;
DR   B1LGW8, GLND_ECOSM ;  Q1RG23, GLND_ECOUT ;  A7MGS0, GLND_ENTS8 ;
DR   Q6D8E5, GLND_ERWCT ;  Q2N784, GLND_ERYLH ;  B7LWA6, GLND_ESCF3 ;
DR   Q5FPT6, GLND_GLUOX ;  Q4QJM6, GLND_HAEI8 ;  A5UBF9, GLND_HAEIE ;
DR   P43919, GLND_HAEIN ;  Q5QXT0, GLND_IDILO ;  P41393, GLND_KLEOX ;
DR   Q5X4J1, GLND_LEGPA ;  A5ICM0, GLND_LEGPC ;  Q5ZUS2, GLND_LEGPH ;
DR   Q5WVX6, GLND_LEGPL ;  Q65SZ8, GLND_MANSM ;  Q60BB2, GLND_METCA ;
DR   A5U6S3, GLND_MYCTA ;  Q10961, GLND_MYCTU ;  Q5F8H5, GLND_NEIG1 ;
DR   B4RLK3, GLND_NEIG2 ;  A9LZ86, GLND_NEIM0 ;  Q9JUC9, GLND_NEIMA ;
DR   Q9JZB4, GLND_NEIMB ;  A1KU16, GLND_NEIMF ;  Q1QRM1, GLND_NITHX ;
DR   Q2Y5Q1, GLND_NITMU ;  Q3JCX7, GLND_NITOC ;  Q3SWE0, GLND_NITWN ;
DR   Q2GAJ4, GLND_NOVAD ;  A6WV84, GLND_OCHA4 ;  Q9CNH1, GLND_PASMU ;
DR   C6DAI1, GLND_PECCP ;  B4RC79, GLND_PHEZH ;  Q7N8P9, GLND_PHOLL ;
DR   Q6LN22, GLND_PHOPR ;  Q48F57, GLND_PSE14 ;  A6V1D0, GLND_PSEA7 ;
DR   B7V7F5, GLND_PSEA8 ;  Q02RD0, GLND_PSEAB ;  Q9Z9H0, GLND_PSEAE ;
DR   Q1I624, GLND_PSEE4 ;  Q4KHH8, GLND_PSEF5 ;  C3K5E4, GLND_PSEFS ;
DR   Q3IIZ7, GLND_PSEHT ;  A4XWU3, GLND_PSEMY ;  A5W852, GLND_PSEP1 ;
DR   Q3KHB4, GLND_PSEPF ;  B0KS97, GLND_PSEPG ;  Q88MI2, GLND_PSEPK ;
DR   B1JBR2, GLND_PSEPW ;  Q886P5, GLND_PSESM ;  Q4ZWT0, GLND_PSEU2 ;
DR   A4VJR9, GLND_PSEU5 ;  Q4FUP5, GLND_PSYA2 ;  Q1QDM9, GLND_PSYCK ;
DR   A5WCX0, GLND_PSYWF ;  Q1LNG0, GLND_RALME ;  Q8XZJ3, GLND_RALSO ;
DR   Q98C27, GLND_RHILO ;  Q9RAE4, GLND_RHILV ;  P56884, GLND_RHIME ;
DR   Q53245, GLND_RHITR ;  P62223, GLND_RHOPA ;  Q2RNG2, GLND_RHORT ;
DR   Q3J5H6, GLND_RHOS4 ;  B5F8S8, GLND_SALA4 ;  A9MPJ5, GLND_SALAR ;
DR   Q57T41, GLND_SALCH ;  B5FJ14, GLND_SALDC ;  B5R3H9, GLND_SALEP ;
DR   B5RHF2, GLND_SALG2 ;  B4TK42, GLND_SALHS ;  B4SUZ6, GLND_SALNS ;
DR   Q5PD56, GLND_SALPA ;  B5BL94, GLND_SALPK ;  B4TXR9, GLND_SALSV ;
DR   Q8Z9A7, GLND_SALTI ;  P23679, GLND_SALTY ;  A8GIE8, GLND_SERP5 ;
DR   Q8EGH8, GLND_SHEON ;  B2U309, GLND_SHIB3 ;  Q325X3, GLND_SHIBS ;
DR   Q32JU2, GLND_SHIDS ;  Q0T842, GLND_SHIF8 ;  Q83MD4, GLND_SHIFL ;
DR   Q3Z5J1, GLND_SHISS ;  Q5LWE5, GLND_SILPO ;  A6U5G1, GLND_SINMW ;
DR   Q2NRK5, GLND_SODGM ;  O69873, GLND_STRCO ;  Q31G41, GLND_THICR ;
DR   Q3SKP1, GLND_THIDA ;  Q9KPV0, GLND_VIBCH ;  Q9XC07, GLND_VIBF1 ;
DR   B5F9X8, GLND_VIBFM ;  A7N1X9, GLND_VIBHB ;  Q87MD6, GLND_VIBPA ;
DR   B7VIS0, GLND_VIBSL ;  Q8DBG3, GLND_VIBVU ;  Q7MIF8, GLND_VIBVY ;
DR   Q8PMJ8, GLND_XANAC ;  Q3BVJ6, GLND_XANC5 ;  Q4USS0, GLND_XANC8 ;
DR   B0RW57, GLND_XANCB ;  Q8PAU4, GLND_XANCP ;  Q2P497, GLND_XANOM ;
DR   Q5H1D3, GLND_XANOR ;  A1JP85, GLND_YERE8 ;  A7FFG7, GLND_YERP3 ;
DR   Q1CAN8, GLND_YERPA ;  Q8ZH68, GLND_YERPE ;  A9R397, GLND_YERPG ;
DR   Q1CFE4, GLND_YERPN ;  A4TL94, GLND_YERPP ;  Q667I7, GLND_YERPS ;
DR   Q5NPH0, GLND_ZYMMO ;
//
ID   2.7.7.60
DE   2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase.
AN   4-diphosphocytidyl-2-C-methyl-D-erythritol synthase.
AN   MCT.
AN   MEP cytidylyltransferase.
CA   CTP + 2-C-methyl-D-erythritol 4-phosphate = diphosphate + 4-(cytidine
CA   5'-diphospho)-2-C-methyl-D-erythritol.
CF   Manganese or magnesium.
CC   -!- ATP or UTP can replace CTP, but both are less effective.
CC   -!- GTP and TTP are not substrates.
CC   -!- Forms part of an alternative nonmevalonate pathway for terpenoid
CC       biosynthesis.
DR   Q92F40, ISPD1_LISIN;  Q724H7, ISPD1_LISMF;  Q8YAB5, ISPD1_LISMO;
DR   Q2YV76, ISPD1_STAAB;  Q5HJC5, ISPD1_STAAC;  P65176, ISPD1_STAAM;
DR   P65177, ISPD1_STAAN;  Q6GK63, ISPD1_STAAR;  Q6GCM3, ISPD1_STAAS;
DR   Q8NYI0, ISPD1_STAAW;  Q87LQ2, ISPD1_VIBPA;  Q92CV0, ISPD2_LISIN;
DR   Q720Y7, ISPD2_LISMF;  Q8Y832, ISPD2_LISMO;  Q2YV73, ISPD2_STAAB;
DR   Q5HJC1, ISPD2_STAAC;  Q99WW8, ISPD2_STAAM;  Q7A7V0, ISPD2_STAAN;
DR   Q6GK57, ISPD2_STAAR;  Q6GCL7, ISPD2_STAAS;  Q7A1W0, ISPD2_STAAW;
DR   Q87Q30, ISPD2_VIBPA;  B9JF01, ISPDF_AGRRK;  Q8UFF4, ISPDF_AGRT5;
DR   B9JW91, ISPDF_AGRVS;  Q2IQG8, ISPDF_ANADE;  A7HDA2, ISPDF_ANADF;
DR   A8ER37, ISPDF_ARCB4;  A8IBL6, ISPDF_AZOC5;  A1USA2, ISPDF_BARBK;
DR   Q6G3Z8, ISPDF_BARHE;  Q6G164, ISPDF_BARQU;  A9IS87, ISPDF_BART1;
DR   Q89LQ8, ISPDF_BRAJA;  A5EIY9, ISPDF_BRASB;  A4YUQ7, ISPDF_BRASO;
DR   Q2YPW1, ISPDF_BRUA2;  Q57D18, ISPDF_BRUAB;  Q8YHD8, ISPDF_BRUME;
DR   A5VQP4, ISPDF_BRUO2;  Q8G0H4, ISPDF_BRUSU;  A7ZCQ2, ISPDF_CAMC1;
DR   A7GZI1, ISPDF_CAMC5;  A0RN28, ISPDF_CAMFF;  A7I1V2, ISPDF_CAMHC;
DR   A8FNR8, ISPDF_CAMJ8;  A7H5V8, ISPDF_CAMJD;  Q9PM68, ISPDF_CAMJE;
DR   A1W1K9, ISPDF_CAMJJ;  Q5HSI4, ISPDF_CAMJR;  B9KEX3, ISPDF_CAMLR;
DR   B8GW85, ISPDF_CAUCN;  Q9A7I5, ISPDF_CAUCR;  A5CTY4, ISPDF_CLAM3;
DR   B1I0S9, ISPDF_DESAP;  Q310X3, ISPDF_DESDG;  C4XSW4, ISPDF_DESMR;
DR   Q6ARN9, ISPDF_DESPS;  Q72C30, ISPDF_DESVH;  A1VDX6, ISPDF_DESVV;
DR   A8LKV5, ISPDF_DINSH;  Q2NAE1, ISPDF_ERYLH;  Q5FQD6, ISPDF_GLUOX;
DR   Q0BTD5, ISPDF_GRABC;  Q17WU1, ISPDF_HELAH;  Q7VFU3, ISPDF_HELHP;
DR   B6JL03, ISPDF_HELP2;  B5Z6H4, ISPDF_HELPG;  Q1CU78, ISPDF_HELPH;
DR   Q9ZM19, ISPDF_HELPJ;  B2USR1, ISPDF_HELPS;  O25664, ISPDF_HELPY;
DR   Q0C0N0, ISPDF_HYPNA;  Q28Q60, ISPDF_JANSC;  Q1MR76, ISPDF_LAWIP;
DR   Q6ADI0, ISPDF_LEIXX;  Q2W4Q8, ISPDF_MAGSA;  Q0APQ6, ISPDF_MARMM;
DR   Q11HV9, ISPDF_MESSB;  Q1QM99, ISPDF_NITHX;  A6Q2K0, ISPDF_NITSB;
DR   Q3SSN8, ISPDF_NITWN;  Q2G708, ISPDF_NOVAD;  A6X0N1, ISPDF_OCHA4;
DR   A1B890, ISPDF_PARDP;  A7HXV6, ISPDF_PARL1;  Q4FM31, ISPDF_PELUB;
DR   B3PYS4, ISPDF_RHIE6;  Q2K8V5, ISPDF_RHIEC;  Q1MH21, ISPDF_RHIL3;
DR   Q98MX9, ISPDF_RHILO;  B5ZNB6, ISPDF_RHILW;  Q92Q90, ISPDF_RHIME;
DR   Q08113, ISPDF_RHOCB;  Q21YT7, ISPDF_RHOFD;  Q2IW23, ISPDF_RHOP2;
DR   Q07MZ2, ISPDF_RHOP5;  Q6N6M5, ISPDF_RHOPA;  Q214R1, ISPDF_RHOPB;
DR   Q137C3, ISPDF_RHOPS;  B3QIL5, ISPDF_RHOPT;  Q2RTS1, ISPDF_RHORT;
DR   Q5LRN5, ISPDF_SILPO;  Q1GGW9, ISPDF_SILST;  A6U8F8, ISPDF_SINMW;
DR   Q1GTN0, ISPDF_SPHAL;  A5V2U9, ISPDF_SPHWW;  Q30QG7, ISPDF_SULDN;
DR   A6Q7M3, ISPDF_SULNB;  O83525, ISPDF_TREPA;  Q83NK3, ISPDF_TROW8;
DR   Q83MX3, ISPDF_TROWT;  Q73G24, ISPDF_WOLPM;  Q7MQW9, ISPDF_WOLSU;
DR   Q5GSM7, ISPDF_WOLTR;  Q9RNZ1, ISPDF_ZYMMO;  B0C9F6, ISPD_ACAM1 ;
DR   Q6FAU1, ISPD_ACIAD ;  B2I2A2, ISPD_ACIBC ;  B0VQH8, ISPD_ACIBS ;
DR   A3M5X8, ISPD_ACIBT ;  B0V5E6, ISPD_ACIBY ;  C1F763, ISPD_ACIC5 ;
DR   B7J4C0, ISPD_ACIF2 ;  B5EMB5, ISPD_ACIF5 ;  A3N0G2, ISPD_ACTP2 ;
DR   B3H1E1, ISPD_ACTP7 ;  B0BP82, ISPD_ACTPJ ;  A6VQY1, ISPD_ACTSZ ;
DR   A0KGH5, ISPD_AERHH ;  B6EKL6, ISPD_ALISL ;  A6TWL0, ISPD_ALKMQ ;
DR   A8MLB1, ISPD_ALKOO ;  B4RZG5, ISPD_ALTMD ;  B9MJW2, ISPD_ANATD ;
DR   Q3MAF5, ISPD_ANAVT ;  O67343, ISPD_AQUAE ;  P69834, ISPD_ARATH ;
DR   Q5NYJ9, ISPD_AROAE ;  B6YQA2, ISPD_AZOPC ;  A1K644, ISPD_AZOSB ;
DR   A7Z0L2, ISPD_BACA2 ;  A0R8F7, ISPD_BACAH ;  Q81VV5, ISPD_BACAN ;
DR   Q73FC1, ISPD_BACC1 ;  A7GJZ7, ISPD_BACCN ;  Q81J63, ISPD_BACCR ;
DR   Q63HB4, ISPD_BACCZ ;  Q5L917, ISPD_BACFN ;  Q64P77, ISPD_BACFR ;
DR   Q9KGF8, ISPD_BACHD ;  Q6HPT2, ISPD_BACHK ;  Q65PD2, ISPD_BACLD ;
DR   A8F958, ISPD_BACP2 ;  Q5WLT7, ISPD_BACSK ;  Q06755, ISPD_BACSU ;
DR   Q8A0U8, ISPD_BACTN ;  A6KXL8, ISPD_BACV8 ;  A9VN98, ISPD_BACWK ;
DR   Q1LTP8, ISPD_BAUCH ;  B3DTQ9, ISPD_BIFLD ;  Q8G7E2, ISPD_BIFLO ;
DR   B7GMX1, ISPD_BIFLS ;  Q494E8, ISPD_BLOPB ;  Q7WCW3, ISPD_BORBR ;
DR   Q7W5C9, ISPD_BORPA ;  A9II44, ISPD_BORPD ;  Q7VZN2, ISPD_BORPE ;
DR   P57495, ISPD_BUCAI ;  Q8K9D6, ISPD_BUCAP ;  Q1BHA5, ISPD_BURCA ;
DR   A0K867, ISPD_BURCH ;  B4EC23, ISPD_BURCJ ;  Q0BED6, ISPD_BURCM ;
DR   A9AIT5, ISPD_BURM1 ;  A3MKM4, ISPD_BURM7 ;  A2SBD6, ISPD_BURM9 ;
DR   Q62JI5, ISPD_BURMA ;  A1V500, ISPD_BURMS ;  A3NWE0, ISPD_BURP0 ;
DR   Q3JR99, ISPD_BURP1 ;  A3NAL9, ISPD_BURP6 ;  B2JGK2, ISPD_BURP8 ;
DR   B2T3X2, ISPD_BURPP ;  Q63T70, ISPD_BURPS ;  Q39FB8, ISPD_BURS3 ;
DR   Q2SWT6, ISPD_BURTA ;  A4JF20, ISPD_BURVG ;  Q13Z31, ISPD_BURXL ;
DR   A4XLJ3, ISPD_CALS8 ;  Q3A9N7, ISPD_CARHZ ;  Q5L6V2, ISPD_CHLAB ;
DR   Q3AS33, ISPD_CHLCH ;  Q824I4, ISPD_CHLCV ;  Q253C1, ISPD_CHLFF ;
DR   Q9PJT1, ISPD_CHLMU ;  B3QP85, ISPD_CHLP8 ;  B3EQ34, ISPD_CHLPB ;
DR   Q9Z7X5, ISPD_CHLPN ;  B0B835, ISPD_CHLT2 ;  B3QXK8, ISPD_CHLT3 ;
DR   Q3KLN6, ISPD_CHLTA ;  B0BCA0, ISPD_CHLTB ;  Q8KCU3, ISPD_CHLTE ;
DR   O84468, ISPD_CHLTR ;  Q1QU73, ISPD_CHRSD ;  Q7NYL6, ISPD_CHRVO ;
DR   A8ANW1, ISPD_CITK8 ;  Q97EC9, ISPD_CLOAB ;  A7FZ94, ISPD_CLOB1 ;
DR   C3KVS6, ISPD_CLOB6 ;  A6LPN9, ISPD_CLOB8 ;  B2TIF4, ISPD_CLOBB ;
DR   A5I7N1, ISPD_CLOBH ;  C1FMX6, ISPD_CLOBJ ;  B1IGH9, ISPD_CLOBK ;
DR   A7GJ99, ISPD_CLOBL ;  B1KTA8, ISPD_CLOBM ;  Q18CD1, ISPD_CLOD6 ;
DR   B9DY87, ISPD_CLOK1 ;  A5N4M5, ISPD_CLOK5 ;  A0PXS4, ISPD_CLONN ;
DR   Q0TMM2, ISPD_CLOP1 ;  Q8XHQ3, ISPD_CLOPE ;  A9KSU6, ISPD_CLOPH ;
DR   Q0SQB9, ISPD_CLOPS ;  Q890M1, ISPD_CLOTE ;  Q487E9, ISPD_COLP3 ;
DR   Q6NFC1, ISPD_CORDI ;  Q8FMI3, ISPD_COREF ;  A4QH60, ISPD_CORGB ;
DR   Q8NMB8, ISPD_CORGL ;  Q4JXJ7, ISPD_CORJK ;  Q472F2, ISPD_CUPPJ ;
DR   B1WSY4, ISPD_CYAA5 ;  Q47EL2, ISPD_DECAR ;  Q3ZAD7, ISPD_DEHE1 ;
DR   A5FP88, ISPD_DEHSB ;  Q3ZWE1, ISPD_DEHSC ;  Q1J200, ISPD_DEIGD ;
DR   Q9RR90, ISPD_DEIRA ;  A4J0Y3, ISPD_DESRM ;  B5YF77, ISPD_DICT6 ;
DR   A7ZQJ1, ISPD_ECO24 ;  B7UHG6, ISPD_ECO27 ;  B7MKM1, ISPD_ECO45 ;
DR   B7LEG5, ISPD_ECO55 ;  Q8X7Y4, ISPD_ECO57 ;  B5Z3A9, ISPD_ECO5E ;
DR   B7NT91, ISPD_ECO7I ;  B7MYQ2, ISPD_ECO81 ;  B7LXF9, ISPD_ECO8A ;
DR   C4ZZQ1, ISPD_ECOBW ;  B1XCS3, ISPD_ECODH ;  A8A3M6, ISPD_ECOHS ;
DR   A1AEU1, ISPD_ECOK1 ;  Q0TEB1, ISPD_ECOL5 ;  Q8FEJ5, ISPD_ECOL6 ;
DR   B1IUT2, ISPD_ECOLC ;  Q46893, ISPD_ECOLI ;  B7N6X7, ISPD_ECOLU ;
DR   B6I6D7, ISPD_ECOSE ;  B1LQ67, ISPD_ECOSM ;  Q1R7U4, ISPD_ECOUT ;
DR   A4WDV2, ISPD_ENT38 ;  A7MJ57, ISPD_ENTS8 ;  Q6D1B3, ISPD_ERWCT ;
DR   B7LWK8, ISPD_ESCF3 ;  C4Z312, ISPD_EUBE2 ;  Q2J542, ISPD_FRASC ;
DR   Q8R6H2, ISPD_FUSNN ;  Q5L433, ISPD_GEOKA ;  Q39ZL5, ISPD_GEOMG ;
DR   Q746Z9, ISPD_GEOSL ;  A4IJG4, ISPD_GEOTN ;  A5G938, ISPD_GEOUR ;
DR   Q7NGU6, ISPD_GLOVI ;  Q7VLT5, ISPD_HAEDU ;  Q4QMP4, ISPD_HAEI8 ;
DR   A5UE59, ISPD_HAEIE ;  A5UHG1, ISPD_HAEIG ;  O05029, ISPD_HAEIN ;
DR   Q2SKW7, ISPD_HAHCH ;  A1WWZ0, ISPD_HALHL ;  Q5QUC3, ISPD_IDILO ;
DR   B5XV34, ISPD_KLEP3 ;  A6TD39, ISPD_KLEP7 ;  Q03A83, ISPD_LACC3 ;
DR   Q88W46, ISPD_LACPL ;  C1D558, ISPD_LARHH ;  Q04VR0, ISPD_LEPBJ ;
DR   Q04XR1, ISPD_LEPBL ;  Q72P59, ISPD_LEPIC ;  Q8F7A0, ISPD_LEPIN ;
DR   B1HNM7, ISPD_LYSSC ;  Q65Q78, ISPD_MANSM ;  Q604M2, ISPD_METCA ;
DR   B0JUF7, ISPD_MICAN ;  Q2RFM0, ISPD_MOOTA ;  Q7TW54, ISPD_MYCBO ;
DR   A1KPR8, ISPD_MYCBP ;  C1AI41, ISPD_MYCBT ;  B8ZUA7, ISPD_MYCLB ;
DR   Q9CCW6, ISPD_MYCLE ;  B2HJ23, ISPD_MYCMM ;  Q743W5, ISPD_MYCPA ;
DR   A5U8Q7, ISPD_MYCTA ;  P96864, ISPD_MYCTU ;  A0PV29, ISPD_MYCUA ;
DR   Q5F829, ISPD_NEIG1 ;  B4RL14, ISPD_NEIG2 ;  A9M0U7, ISPD_NEIM0 ;
DR   Q9JTM3, ISPD_NEIMA ;  Q9JYM4, ISPD_NEIMB ;  A1KUV0, ISPD_NEIMF ;
DR   Q2GEM3, ISPD_NEOSM ;  Q0AFW3, ISPD_NITEC ;  Q82UR9, ISPD_NITEU ;
DR   Q2Y751, ISPD_NITMU ;  Q3JCS9, ISPD_NITOC ;  Q5Z2R3, ISPD_NOCFA ;
DR   B2J1D2, ISPD_NOSP7 ;  Q8YLX9, ISPD_NOSS1 ;  Q6MEE8, ISPD_PARUW ;
DR   P57953, ISPD_PASMU ;  C6DDG2, ISPD_PECCP ;  Q3A8C6, ISPD_PELCD ;
DR   Q3B3A7, ISPD_PELLD ;  B4SAG7, ISPD_PELPB ;  A5D5L4, ISPD_PELTS ;
DR   A9BHR2, ISPD_PETMO ;  Q7N8K7, ISPD_PHOLL ;  Q6LMT3, ISPD_PHOPR ;
DR   B2RJ15, ISPD_PORG3 ;  Q7MUQ9, ISPD_PORGI ;  B4S8U7, ISPD_PROA2 ;
DR   Q6AAV8, ISPD_PROAC ;  A3PBH7, ISPD_PROM0 ;  A8G3G9, ISPD_PROM2 ;
DR   A9BE76, ISPD_PROM4 ;  A2BVB5, ISPD_PROM5 ;  Q31C80, ISPD_PROM9 ;
DR   Q7VDC7, ISPD_PROMA ;  Q7V647, ISPD_PROMM ;  Q7V2M1, ISPD_PROMP ;
DR   A2BPT7, ISPD_PROMS ;  Q46GW4, ISPD_PROMT ;  A4SF04, ISPD_PROVI ;
DR   Q48F81, ISPD_PSE14 ;  Q15P31, ISPD_PSEA6 ;  A6V1F5, ISPD_PSEA7 ;
DR   Q02RA5, ISPD_PSEAB ;  P57707, ISPD_PSEAE ;  Q1I648, ISPD_PSEE4 ;
DR   Q4KHF4, ISPD_PSEF5 ;  C3K6H8, ISPD_PSEFS ;  Q3IDQ6, ISPD_PSEHT ;
DR   A4XWR9, ISPD_PSEMY ;  A5W827, ISPD_PSEP1 ;  Q3KH90, ISPD_PSEPF ;
DR   B0KSC1, ISPD_PSEPG ;  Q88MF7, ISPD_PSEPK ;  B1JB36, ISPD_PSEPW ;
DR   Q886M1, ISPD_PSESM ;  Q4ZWQ6, ISPD_PSEU2 ;  Q4FR76, ISPD_PSYA2 ;
DR   Q1Q9K8, ISPD_PSYCK ;  Q8XYW3, ISPD_RALSO ;  Q7UM15, ISPD_RHOBA ;
DR   C0ZPR7, ISPD_RHOE4 ;  C1BAC2, ISPD_RHOOB ;  A3PJQ3, ISPD_RHOS1 ;
DR   Q3J2K9, ISPD_RHOS4 ;  A4WSL5, ISPD_RHOS5 ;  B9KSH8, ISPD_RHOSK ;
DR   Q0S890, ISPD_RHOSR ;  Q165P6, ISPD_ROSDO ;  Q1AU08, ISPD_RUBXD ;
DR   A1AX25, ISPD_RUTMC ;  A4F6W3, ISPD_SACEN ;  B5F411, ISPD_SALA4 ;
DR   A9MF28, ISPD_SALAR ;  Q57KJ4, ISPD_SALCH ;  B5FTS5, ISPD_SALDC ;
DR   B5QW18, ISPD_SALEP ;  B5RDQ3, ISPD_SALG2 ;  B4TFW7, ISPD_SALHS ;
DR   B4T457, ISPD_SALNS ;  Q5PEG1, ISPD_SALPA ;  A9N2D3, ISPD_SALPB ;
DR   C0PXA7, ISPD_SALPC ;  B5BEY4, ISPD_SALPK ;  Q2S210, ISPD_SALRD ;
DR   B4TTW1, ISPD_SALSV ;  Q8Z471, ISPD_SALTI ;  Q8ZMF6, ISPD_SALTY ;
DR   A8G9Z2, ISPD_SERP5 ;  A1S4D9, ISPD_SHEAM ;  Q12PZ2, ISPD_SHEDO ;
DR   Q086A8, ISPD_SHEFN ;  B0TK06, ISPD_SHEHH ;  A3QC79, ISPD_SHELP ;
DR   Q8EBR2, ISPD_SHEON ;  A8H1S7, ISPD_SHEPA ;  B8CJP8, ISPD_SHEPW ;
DR   A8FST0, ISPD_SHESH ;  B2TZI4, ISPD_SHIB3 ;  Q31XA9, ISPD_SHIBS ;
DR   Q32CI3, ISPD_SHIDS ;  Q0T1H8, ISPD_SHIF8 ;  Q7C093, ISPD_SHIFL ;
DR   Q3YYB5, ISPD_SHISS ;  Q2NVM4, ISPD_SODGM ;  Q027G1, ISPD_SOLUE ;
DR   Q2FK15, ISPD_STAA3 ;  Q2G1C0, ISPD_STAA8 ;  Q5HRJ7, ISPD_STAEQ ;
DR   Q8CQ77, ISPD_STAES ;  Q4A0A8, ISPD_STAS1 ;  Q3K093, ISPD_STRA1 ;
DR   Q8E4B4, ISPD_STRA3 ;  Q8DYQ7, ISPD_STRA5 ;  Q82GC8, ISPD_STRAW ;
DR   Q9L0Q8, ISPD_STRCO ;  B4SR88, ISPD_STRM5 ;  B2FK90, ISPD_STRMK ;
DR   Q04K52, ISPD_STRP2 ;  B5E508, ISPD_STRP4 ;  C1C7P9, ISPD_STRP7 ;
DR   B1IC62, ISPD_STRPI ;  B8ZJT5, ISPD_STRPJ ;  Q97QE5, ISPD_STRPN ;
DR   B2IQ63, ISPD_STRPS ;  Q8DPI2, ISPD_STRR6 ;  C1CEM5, ISPD_STRZJ ;
DR   C1CL05, ISPD_STRZP ;  C1CR35, ISPD_STRZT ;  Q67JP5, ISPD_SYMTH ;
DR   Q2LUS9, ISPD_SYNAS ;  Q31QF6, ISPD_SYNE7 ;  A0LIS2, ISPD_SYNFM ;
DR   Q2JUE5, ISPD_SYNJA ;  Q5N3T2, ISPD_SYNP6 ;  A5GMW9, ISPD_SYNPW ;
DR   Q7U559, ISPD_SYNPX ;  Q0I880, ISPD_SYNS3 ;  Q3AWK9, ISPD_SYNS9 ;
DR   Q3ALY8, ISPD_SYNSC ;  P74323, ISPD_SYNY3 ;  B7IF61, ISPD_THEAB ;
DR   Q8DL91, ISPD_THEEB ;  Q47LV0, ISPD_THEFY ;  A6LPA6, ISPD_THEM4 ;
DR   Q9X1B3, ISPD_THEMA ;  B9K8U1, ISPD_THENN ;  A5IMI1, ISPD_THEP1 ;
DR   B1LBT2, ISPD_THESQ ;  Q72GN3, ISPD_THET2 ;  Q5SLX2, ISPD_THET8 ;
DR   Q8R7S6, ISPD_THETN ;  Q3SK38, ISPD_THIDA ;  C4LBQ9, ISPD_TOLAT ;
DR   Q118M1, ISPD_TRIEI ;  B1GYT4, ISPD_UNCTG ;  A5CW51, ISPD_VESOH ;
DR   Q9KUJ2, ISPD_VIBCH ;  Q5E328, ISPD_VIBF1 ;  B5FAF7, ISPD_VIBFM ;
DR   B7VK66, ISPD_VIBSL ;  Q8DC60, ISPD_VIBVU ;  Q7MHQ4, ISPD_VIBVY ;
DR   Q8D223, ISPD_WIGBR ;  Q8PLR8, ISPD_XANAC ;  Q3BUS8, ISPD_XANC5 ;
DR   Q4UTP4, ISPD_XANC8 ;  B0RU03, ISPD_XANCB ;  Q8P9Z1, ISPD_XANCP ;
DR   Q2P1L0, ISPD_XANOM ;  B2SUA8, ISPD_XANOP ;  Q5GYK6, ISPD_XANOR ;
DR   B2I939, ISPD_XYLF2 ;  Q9PDT6, ISPD_XYLFA ;  B0U660, ISPD_XYLFM ;
DR   Q87DY4, ISPD_XYLFT ;  A7FLX8, ISPD_YERP3 ;  B2K577, ISPD_YERPB ;
DR   Q8ZBP6, ISPD_YERPE ;  A9R119, ISPD_YERPG ;  Q1CLR6, ISPD_YERPN ;
DR   A4TPZ7, ISPD_YERPP ;  Q66EC3, ISPD_YERPS ;  B1JJF8, ISPD_YERPY ;
//
ID   2.7.7.61
DE   Citrate lyase holo-[acyl-carrier-protein] synthase.
AN   2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase.
AN   Holo-ACP synthase.
AN   Holo-citrate lyase synthase.
CA   2'-(5-triphosphoribosyl)-3'-dephospho-CoA + citrate lyase apo-[acyl-
CA   carrier-protein] = citrate lyase holo-[acyl-carrier-protein] +
CA   diphosphate.
CC   -!- The gamma-subunit of EC 4.1.3.6 serves as an acyl-carrier protein
CC       (ACP) and contains the prosthetic group 2'-(5-triphosphoribosyl)-
CC       3'-dephospho-CoA.
CC   -!- Synthesis and attachment of the prosthetic group requires the
CC       concerted action of this enzyme and EC 2.7.8.25.
CC   -!- In the enzyme from Escherichia coli, the prosthetic group is attached
CC       to serine-14 of the ACP via a phosphodiester bond.
DR   P44458, CITXG_HAEIN;  O53080, CITXG_LEUMC;  Q9RLT3, CITXG_WEIPA;
DR   A8AJJ1, CITX_CITK8 ;  A7ZJ00, CITX_ECO24 ;  B7UKQ6, CITX_ECO27 ;
DR   B7MF27, CITX_ECO45 ;  B7L8J7, CITX_ECO55 ;  P0A6G6, CITX_ECO57 ;
DR   B5YPW2, CITX_ECO5E ;  B7NLX4, CITX_ECO7I ;  B7MRQ2, CITX_ECO81 ;
DR   B7M4U6, CITX_ECO8A ;  C4ZWA3, CITX_ECOBW ;  A7ZXP1, CITX_ECOHS ;
DR   A1A8P3, CITX_ECOK1 ;  Q0TK58, CITX_ECOL5 ;  Q8FK03, CITX_ECOL6 ;
DR   B1IYJ2, CITX_ECOLC ;  P0A6G5, CITX_ECOLI ;  B7N9M0, CITX_ECOLU ;
DR   B6I0S3, CITX_ECOSE ;  B1LKK6, CITX_ECOSM ;  Q1REU8, CITX_ECOUT ;
DR   B2TTH7, CITX_SHIB3 ;  Q0T702, CITX_SHIF8 ;  Q3Z4H9, CITX_SHISS ;
DR   P58160, CITX_STRP1 ;  P0DA32, CITX_STRP3 ;  Q5XC31, CITX_STRP6 ;
DR   Q8P0Z2, CITX_STRP8 ;  A2REE2, CITX_STRPG ;  P0DA33, CITX_STRPQ ;
DR   A5F3C5, CITX_VIBC3 ;  Q9KTT8, CITX_VIBCH ;  C3LT53, CITX_VIBCM ;
//
ID   2.7.7.62
DE   Adenosylcobinamide-phosphate guanylyltransferase.
AN   Adenosylcobinamide kinase/adenosylcobinamide-phosphate
AN   guanylyltransferase.
AN   AdoCbi kinase/AdoCbi-phosphate guanylyltransferase.
AN   GTP:adenosylcobinamide-phosphate guanylyltransferase.
CA   GTP + adenosylcobinamide phosphate = diphosphate + adenosylcobinamide-
CA   GDP.
CC   -!- In Salmonella typhimurium LT2, under anaerobic conditions, CobU
CC       (EC 2.7.7.62 and EC 2.7.1.156), CobT (EC 2.4.2.21),
CC       CobC (EC 3.1.3.73) and CobS (EC 2.7.8.26) catalyze reactions in the
CC       nucleotide loop assembly pathway, which convert adenosylcobinamide
CC       (AdoCbi) into adenosylcobalamin (AdoCbl).
CC   -!- CobT and CobC are involved in 5,6-dimethylbenzimidazole activation
CC       whereby 5,6-dimethylbenzimidazole is converted to its riboside,
CC       alpha-ribazole.
CC   -!- The second branch of the nuclotide loop assembly pathway is the
CC       cobinamide (Cbi) activation branch where AdoCbi or
CC       adenosylcobinamide-phosphate is converted to the activated
CC       intermediate AdoCbi-GDP by the bifunctional enzyme CobU.
CC   -!- The final step in adenosylcobalamin biosynthesis is the condensation
CC       of AdoCbi-GDP with alpha-ribazole, which is catalyzed by CobS
CC       (EC 2.7.8.26), to yield adenosylcobalamin.
CC   -!- CobU is a bifunctional enzyme that has both kinase (EC 2.7.1.156) and
CC       guanylyltransferase (EC 2.7.7.62) activities.
CC   -!- However, both activities are not required at all times.
CC   -!- The kinase activity has been proposed to function only when
CC       S.typhimurium is assimilating cobinamide whereas the
CC       guanylyltransferase activity is required for both assimilation of
CC       exogenous cobinamide and for de novo synthesis of adenosylcobalamin.
CC   -!- The guanylyltransferase reaction is a two-stage reaction with
CC       formation of a CobU-GMP intermediate.
DR   Q9I466, COBP_PSEAE ;  P29931, COBP_PSEDE ;  P0AE77, COBU_ECO57 ;
DR   P0AE76, COBU_ECOLI ;  Q05599, COBU_SALTY ;  Q58517, COBY_METJA ;
//
ID   2.7.7.63
DE   Lipoate--protein ligase.
AN   Lipoate protein ligase.
AN   Lipoate-protein ligase A.
AN   LPL.
CA   (1) ATP + lipoate = diphosphate + lipoyl-AMP.
CA   (2) Lipoyl-AMP + protein = protein N(6)-(lipoyl)lysine + AMP.
CF   Magnesium.
CC   -!- Both 6S- and 6R-lipoates can act as substrates but there is a
CC       preference for the naturally occurring R-form.
CC   -!- Selenolipoate, i.e. 5-(1,2-diselenolan-3-yl)pentanoic acid,
CC       and 6-sulfanyloctanoate can also act as substrates, but more slowly.
CC   -!- Responsible for lipoylation in the presence of exogenous lipoic acid.
CC   -!- Lipoylation is essential for the function of several key enzymes
CC       involved in oxidative metabolism, including pyruvate dehydrogenase
CC       (E(2) domain), 2-oxoglutarate dehydrogenase (E(2) domain),
CC       the branched-chain 2-oxoacid dehydrogenases and the glycine cleavage
CC       system (H protein).
CC   -!- Attaches lipoic acid to the lipoyl domains of these proteins.
CC   -!- It is likely that an alternative pathway, involving EC 2.3.1.181 and
CC       EC 2.8.1.8 is the normal route for lipoylation.
DR   Q9HKT2, LPLAC_THEAC;  Q9HKT1, LPLAN_THEAC;  A0KMH0, LPLA_AERHH ;
DR   Q9Y9E6, LPLA_AERPE ;  A4SQ09, LPLA_AERS4 ;  P60809, LPLA_BDEBA ;
DR   Q7VR65, LPLA_BLOFL ;  Q492U9, LPLA_BLOPB ;  A8ALX2, LPLA_CITK8 ;
DR   A7ZVS8, LPLA_ECO24 ;  B7UR14, LPLA_ECO27 ;  B7MNJ3, LPLA_ECO45 ;
DR   B7LEN2, LPLA_ECO55 ;  P60776, LPLA_ECO57 ;  B7NW66, LPLA_ECO7I ;
DR   B7MTD2, LPLA_ECO81 ;  B7LXU8, LPLA_ECO8A ;  C4ZT68, LPLA_ECOBW ;
DR   B1XFJ6, LPLA_ECODH ;  A8A8B4, LPLA_ECOHS ;  A1AJV3, LPLA_ECOK1 ;
DR   Q0T8S7, LPLA_ECOL5 ;  Q8FA49, LPLA_ECOL6 ;  B1IS33, LPLA_ECOLC ;
DR   P32099, LPLA_ECOLI ;  B7NH54, LPLA_ECOLU ;  B6I6N3, LPLA_ECOSE ;
DR   B1LEJ1, LPLA_ECOSM ;  Q1R257, LPLA_ECOUT ;  A4W6A2, LPLA_ENT38 ;
DR   A7MIG6, LPLA_ENTS8 ;  B7LNS6, LPLA_ESCF3 ;  B5Y273, LPLA_KLEP3 ;
DR   A6TI00, LPLA_KLEP7 ;  P47512, LPLA_MYCGE ;  P75394, LPLA_MYCPN ;
DR   C6DKP5, LPLA_PECCP ;  Q1QEC2, LPLA_PSYCK ;  B5F534, LPLA_SALA4 ;
DR   A9MRA3, LPLA_SALAR ;  Q57G36, LPLA_SALCH ;  B5FTD0, LPLA_SALDC ;
DR   B5R2K1, LPLA_SALEP ;  B5R9V4, LPLA_SALG2 ;  B4TH09, LPLA_SALHS ;
DR   B4T4I0, LPLA_SALNS ;  Q5PK29, LPLA_SALPA ;  A9N7E6, LPLA_SALPB ;
DR   C0Q7M8, LPLA_SALPC ;  B5BAK2, LPLA_SALPK ;  B4TU46, LPLA_SALSV ;
DR   Q8Z0U0, LPLA_SALTI ;  Q8ZJV1, LPLA_SALTY ;  O13629, LPLA_SCHPO ;
DR   A8GDS3, LPLA_SERP5 ;  B2TZR8, LPLA_SHIB3 ;  Q31SV2, LPLA_SHIBS ;
DR   Q327K9, LPLA_SHIDS ;  Q3YU08, LPLA_SHISS ;  A5F8E4, LPLA_VIBC3 ;
DR   Q9KS71, LPLA_VIBCH ;  C3LM83, LPLA_VIBCM ;  B3LQ66, LPLA_YEAS1 ;
DR   B5VLD2, LPLA_YEAS6 ;  A6ZPT1, LPLA_YEAS7 ;  P47051, LPLA_YEAST ;
DR   A1JPK8, LPLA_YERE8 ;  A7FHI0, LPLA_YERP3 ;  Q1C748, LPLA_YERPA ;
DR   B2K5K7, LPLA_YERPB ;  Q8ZDY2, LPLA_YERPE ;  A9R087, LPLA_YERPG ;
DR   Q1CII3, LPLA_YERPN ;  A4TIN0, LPLA_YERPP ;  Q66A10, LPLA_YERPS ;
DR   B1JJ36, LPLA_YERPY ;  O07608, LPLJ_BACSU ;
//
ID   2.7.7.64
DE   UTP-monosaccharide-1-phosphate uridylyltransferase.
AN   UDP-sugar pyrophosphorylase.
AN   USP.
CA   UTP + a monosaccharide 1-phosphate = diphosphate + UDP-monosaccharide.
CF   Manganese or magnesium.
CC   -!- The reaction can occur in either direction and it has been postulated
CC       that MgUTP and Mg-diphosphate are the actual substrates.
CC   -!- Catalyzes the formation of UDP-Glc, UDP-Gal, UDP-GlcA, UDP-L-Ara and
CC       UDP-Xyl, showing broad substrate specificity toward monosaccharide
CC       1-phosphates.
CC   -!- Mannose 1-phosphate, L-fucose 1-phosphate and glucose 6-phosphate are
CC       not substrates and UTP cannot be replaced by other nucleotide
CC       triphosphates.
DR   Q09WE7, USP1_SOYBN ;  Q9C5I1, USP_ARATH  ;  Q0GZS3, USP_CUCME  ;
DR   A2YGP6, USP_ORYSI  ;  Q5Z8Y4, USP_ORYSJ  ;  Q5W915, USP_PEA    ;
//
ID   2.7.7.65
DE   Diguanylate cyclase.
AN   DGC.
CA   2 GTP = 2 diphosphate + cyclic di-3',5'-guanylate.
CF   Magnesium; Manganese.
CC   -!- Can be activated by BeF3, a phosphoryl mimic, which results in
CC       dimerization.
CC   -!- Dimerization is required but is not sufficient for diguanylate-
CC       cyclase activity.
CC   -!- Cyclic di-3',5'-guanylate is an intracellular signaling molecule that
CC       controls motility and adhesion in bacterial cells; it was first
CC       identified as having a positive allosteric effect on EC 2.4.1.12.
DR   P0AAP1, ADRA_ECOLI ;  P0AA89, DOSC_ECOLI ;  B8GZM2, PLED_CAUCN ;
DR   Q9A5I5, PLED_CAUCR ;  P75908, YCDT_ECOLI ;  P77302, YDAM_ECOLI ;
DR   P0AA90, YDDV_ECO57 ;  Q320T0, YDDV_SHIBS ;  Q0T466, YDDV_SHIF8 ;
DR   Q83KV7, YDDV_SHIFL ;  Q3Z1N3, YDDV_SHISS ;  P31129, YDEH_ECOLI ;
DR   P76237, YEAJ_ECOLI ;  P76245, YEAP_ECOLI ;  P76330, YEDQ_ECOLI ;
DR   P38097, YEGE_ECOLI ;  P46139, YFIN_ECOLI ;
//
ID   2.7.7.66
DE   Malonate decarboxylase holo-[acyl-carrier-protein] synthase.
AN   Holo ACP synthase.
AN   Holo-malonate-decarboxylase synthase.
CA   2'-(5-triphosphoribosyl)-3'-dephospho-CoA + malonate decarboxylase apo-
CA   [acyl-carrier-protein] = malonate decarboxylase holo-[acyl-carrier-
CA   protein] + diphosphate.
CC   -!- The delta subunit of malonate decarboxylase serves as an an acyl-
CC       carrier protein (ACP) and contains the prosthetic group
CC       2'-(5-triphosphoribosyl)-3'-dephospho-CoA.
CC   -!- Two reactions are involved in the production of the holo-ACP form of
CC       this enzyme.
CC   -!- The first reaction is catalyzed by EC 2.7.8.25.
CC   -!- The resulting prosthetic group is then attached to the ACP subunit
CC       via a phosphodiester linkage to a serine residue, thus forming the
CC       holo form of the enzyme, in a manner analogous to that of
CC       EC 2.7.7.61.
DR   C1DNP9, MDCG_AZOVD ;  Q89XP2, MDCG_BRAJA ;  B5XRA3, MDCG_KLEP3 ;
DR   A6T8R9, MDCG_KLEP7 ;  P71426, MDCG_KLEPN ;  Q9I6S5, MDCG_PSEAE ;
DR   Q4K4G0, MDCG_PSEF5 ;  Q3K5C0, MDCG_PSEPF ;  B0KQS7, MDCG_PSEPG ;
DR   Q9Z448, MDCG_PSEPU ;  B1J9E4, MDCG_PSEPW ;  Q87V59, MDCG_PSESM ;
DR   Q8PPW9, MDCG_XANAC ;  Q3BY34, MDCG_XANC5 ;  Q4UZ66, MDCG_XANC8 ;
DR   B0RN93, MDCG_XANCB ;  Q8P4U3, MDCG_XANCP ;
//
ID   2.7.7.67
DE   CDP-archaeol synthase.
CA   CTP + 2,3-bis-O-(geranylgeranyl)-sn-glycero-1-phosphate = diphosphate +
CA   CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol.
CF   Magnesium; Potassium.
CC   -!- Catalyzes one of the steps in the biosynthesis of polar lipids in
CC       archaea, which are characterized by having an sn-glycero-1-phosphate
CC       backbone rather than an sn-glycero-3-phosphate backbone as is found
CC       in bacteria and eukaryotes.
CC   -!- The other enzymes involved in the biosynthesis of polar lipids in
CC       archaea are EC 1.1.1.261, EC 2.5.1.41 and EC 2.5.1.42, which together
CC       alkylate the hydroxy groups of glycerol 1-phosphate to give
CC       unsaturated archaetidic acid, which is acted upon by this enzyme to
CC       form CDP-unsaturated archaeol.
CC   -!- The final step in the pathway involves the addition of L-serine, with
CC       concomitant removal of CMP, leading to the production of unsaturated
CC       archaetidylserine.
CC   -!- Formerly EC 2.7.7.n2.
//
ID   2.7.7.68
DE   2-phospho-L-lactate guanylyltransferase.
CA   (2S)-2-phospholactate + GTP = (2S)-lactyl-2-diphospho-5'-guanosine +
CA   diphosphate.
CC   -!- This enzyme is involved in the biosynthesis of coenzyme F420,
CC       a redox-active cofactor found in all methanogenic archaea, as well as
CC       some eubacteria.
DR   Q0S2F9, COFC1_RHOSR;  Q0RVJ9, COFC2_RHOSR;  O28218, COFC_ARCFU ;
DR   D2RFQ5, COFC_ARCPA ;  A9WC63, COFC_CHLAA ;  B8G4W8, COFC_CHLAD ;
DR   B9LHE7, COFC_CHLSY ;  Q47WW8, COFC_COLP3 ;  D3F5L6, COFC_CONWI ;
DR   D3RZQ1, COFC_FERPA ;  Q2J6X4, COFC_FRASC ;  D2SEH8, COFC_GEOOG ;
DR   B9LQ33, COFC_HALLT ;  Q5UXM7, COFC_HALMA ;  C7P363, COFC_HALMD ;
DR   B0R6P7, COFC_HALS3 ;  Q9HNV0, COFC_HALSA ;  D2RWE9, COFC_HALTV ;
DR   C7NN78, COFC_HALUD ;  D4GVD5, COFC_HALVD ;  Q18FK8, COFC_HALWD ;
DR   A6UUS0, COFC_META3 ;  Q8TQQ2, COFC_METAC ;  A7IAF1, COFC_METB6 ;
DR   Q466A1, COFC_METBF ;  Q12WF3, COFC_METBU ;  C7P592, COFC_METFA ;
DR   Q2FQJ1, COFC_METHJ ;  D5VSX2, COFC_METIM ;  Q58297, COFC_METJA ;
DR   Q8TXS3, COFC_METKA ;  A2ST69, COFC_METLZ ;  A4G074, COFC_METM5 ;
DR   A9A8H9, COFC_METM6 ;  A6VIA6, COFC_METM7 ;  Q8PU52, COFC_METMA ;
DR   A3CWL3, COFC_METMJ ;  Q6M101, COFC_METMP ;  D5E7G9, COFC_METMS ;
DR   B8GKC0, COFC_METPE ;  D1Z1G0, COFC_METPS ;  D3E2P3, COFC_METRM ;
DR   A5UJW5, COFC_METS3 ;  D3S534, COFC_METSF ;  Q2NFK9, COFC_METST ;
DR   O26710, COFC_METTH ;  A0B5I5, COFC_METTP ;  C9REF5, COFC_METVM ;
DR   A6URA0, COFC_METVS ;  B1MDP6, COFC_MYCA9 ;  Q7TXH8, COFC_MYCBO ;
DR   A1KMX7, COFC_MYCBP ;  C1AG98, COFC_MYCBT ;  A4TE28, COFC_MYCGI ;
DR   B8ZS07, COFC_MYCLB ;  O33128, COFC_MYCLE ;  B2HII6, COFC_MYCMM ;
DR   Q73VJ2, COFC_MYCPA ;  A0QUZ4, COFC_MYCS2 ;  A3PXR7, COFC_MYCSJ ;
DR   A1UEB3, COFC_MYCSK ;  Q1BAP9, COFC_MYCSS ;  A5U6Z4, COFC_MYCTA ;
DR   A5WRN6, COFC_MYCTF ;  C6DW66, COFC_MYCTK ;  P95112, COFC_MYCTU ;
DR   A0PQ01, COFC_MYCUA ;  A1T705, COFC_MYCVP ;  D3SYZ8, COFC_NATMM ;
DR   Q3IRF2, COFC_NATPD ;  Q5YRY5, COFC_NOCFA ;  B6JBS5, COFC_OLICO ;
DR   B4RGP0, COFC_PHEZH ;  C0ZXN6, COFC_RHOE4 ;  C1B2N5, COFC_RHOOB ;
DR   A7NR17, COFC_ROSCS ;  A5USE3, COFC_ROSS1 ;  Q1AXF2, COFC_RUBXD ;
DR   A8M5I9, COFC_SALAI ;  D1BJD0, COFC_SANKS ;  D1C883, COFC_SPHTD ;
DR   Q82JS2, COFC_STRAW ;  Q9ZBS2, COFC_STRCO ;  D2AVM1, COFC_STRRD ;
DR   C9Z3U4, COFC_STRSW ;  D1AB53, COFC_THECD ;  B9L4T8, COFC_THERP ;
DR   D1CDA4, COFC_THET1 ;  Q0W6V1, COFC_UNCMA ;
//
ID   2.7.7.69
DE   GDP-L-galactose phosphorylase.
CA   GDP-L-galactose + phosphate = alpha-L-galactose 1-phosphate + GDP.
CC   -!- The enzyme catalyzes a reaction of the Smirnoff-Wheeler pathway,
CC       the major route to ascorbate biosynthesis in plants.
DR   Q8RWE8, GGAP1_ARATH;  Q9FLP9, GGAP2_ARATH;
//
ID   2.7.7.70
DE   D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase.
AN   D-glycero-D-manno-heptose-1-beta-phosphate adenylyltransferase.
CA   D-glycero-beta-D-manno-heptose 1-phosphate + ATP = ADP-D-glycero-beta-D-
CA   manno-heptose + diphosphate.
CC   -!- The bifunctional protein hldE includes D-glycero-beta-D-manno-
CC       heptose-7-phosphate kinase and D-glycero-beta-D-manno-heptose
CC       1-phosphate adenylyltransferase activity (cf. EC 2.7.1.167).
CC   -!- The enzyme is involved in biosynthesis of ADP-L-glycero-beta-D-manno-
CC       heptose, which is utilized for assembly of the lipopolysaccharide
CC       inner core in Gram-negative bacteria.
//
ID   2.7.7.71
DE   D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase.
CA   D-glycero-alpha-D-manno-heptose 1-phosphate + GTP = GDP-D-glycero-alpha-
CA   D-manno-heptose + diphosphate.
CC   -!- The enzyme is involved in biosynthesis of GDP-D-glycero-alpha-D-
CC       manno-heptose, which is required for assembly of S-layer glycoprotein
CC       in some Gram-positive bacteria.
//
ID   2.7.7.72
DE   CCA tRNA nucleotidyltransferase.
AN   CCA-adding enzyme.
AN   Ribonucleic cytidylic cytidylic adenylic pyrophosphorylase.
AN   Transfer ribonucleic adenylyl (cytidylyl) transferase.
AN   Transfer RNA adenylyltransferase.
AN   Transfer-RNA nucleotidyltransferase.
AN   tRNA adenylyl(cytidylyl)transferase.
AN   tRNA CCA-diphosphorylase.
AN   tRNA cytidylyltransferase.
AN   tRNA-nucleotidyltransferase.
CA   A tRNA precursor + 2 CTP + ATP = a tRNA with a 3' CCA end +
CA   3 diphosphate.
CC   -!- The acylation of all tRNAs with an amino acid occurs at the terminal
CC       ribose of a 3' CCA sequence.
CC   -!- The CCA sequence is added to the tRNA precursor by stepwise
CC       nucleotide addition performed by a single enzyme that is ubiquitous
CC       in all living organisms.
CC   -!- Although the enzyme has the option of releasing the product after
CC       each addition, it prefers to stay bound to the product and proceed
CC       with the next addition.
CC   -!- Formerly EC 2.7.7.21 and EC 2.7.7.25.
DR   Q9P4S5, CCA1_CANGA ;  Q9UTQ0, CCA1_SCHPO ;  P21269, CCA1_YEAST ;
DR   Q9Y7U9, CCA2_SCHPO ;  A1TUW0, CCA_ACIAC  ;  Q6FA38, CCA_ACIAD  ;
DR   B7GZN3, CCA_ACIB3  ;  B7I3L8, CCA_ACIB5  ;  B2HV23, CCA_ACIBC  ;
DR   B0VUU0, CCA_ACIBS  ;  A3M767, CCA_ACIBT  ;  B0VBE4, CCA_ACIBY  ;
DR   B9MCK1, CCA_ACIET  ;  A1W3D0, CCA_ACISJ  ;  A3N0S5, CCA_ACTP2  ;
DR   B3GXR2, CCA_ACTP7  ;  A6VN94, CCA_ACTSZ  ;  A0KPN1, CCA_AERHH  ;
DR   P45749, CCA_AERHY  ;  Q9YB04, CCA_AERPE  ;  A4SIG1, CCA_AERS4  ;
DR   Q0VMU8, CCA_ALCBS  ;  Q0ACP8, CCA_ALHEH  ;  B6EM10, CCA_ALISL  ;
DR   B4RVV4, CCA_ALTMD  ;  B7GHS8, CCA_ANOFW  ;  O28126, CCA_ARCFU  ;
DR   Q5P3T0, CCA_AROAE  ;  A1K2Q5, CCA_AZOSB  ;  C1DIX6, CCA_AZOVD  ;
DR   A7Z5Z6, CCA_BACA2  ;  C3P5Q6, CCA_BACAA  ;  C3L8Q3, CCA_BACAC  ;
DR   Q81ST6, CCA_BACAN  ;  B7JH21, CCA_BACC0  ;  Q73AV7, CCA_BACC1  ;
DR   B7IPB4, CCA_BACC2  ;  C1EN33, CCA_BACC3  ;  B7HHU0, CCA_BACC4  ;
DR   B7HL50, CCA_BACC7  ;  A7GN74, CCA_BACCN  ;  B9IVQ9, CCA_BACCQ  ;
DR   Q81FP0, CCA_BACCR  ;  Q63DJ6, CCA_BACCZ  ;  Q9KC89, CCA_BACHD  ;
DR   Q6HL19, CCA_BACHK  ;  Q65I54, CCA_BACLD  ;  A8FEH9, CCA_BACP2  ;
DR   Q5WGA1, CCA_BACSK  ;  P42977, CCA_BACSU  ;  A9VME7, CCA_BACWK  ;
DR   Q1LSL7, CCA_BAUCH  ;  Q7U350, CCA_BLOFL  ;  Q493X4, CCA_BLOPB  ;
DR   Q7U391, CCA_BORBR  ;  Q7U367, CCA_BORPA  ;  Q7U358, CCA_BORPE  ;
DR   B8D8L9, CCA_BUCA5  ;  P57169, CCA_BUCAI  ;  Q8KA53, CCA_BUCAP  ;
DR   B8D6X3, CCA_BUCAT  ;  Q89B06, CCA_BUCBP  ;  Q058D0, CCA_BUCCC  ;
DR   B1YPB3, CCA_BURA4  ;  Q1BST9, CCA_BURCA  ;  B1JZZ7, CCA_BURCC  ;
DR   A0KBA2, CCA_BURCH  ;  B4E8K1, CCA_BURCJ  ;  Q0BB41, CCA_BURCM  ;
DR   A9ABP3, CCA_BURM1  ;  A3MRJ1, CCA_BURM7  ;  A2S800, CCA_BURM9  ;
DR   Q62EU1, CCA_BURMA  ;  A1V7S8, CCA_BURMS  ;  A3NQD4, CCA_BURP0  ;
DR   A3N4P2, CCA_BURP6  ;  B2JIM3, CCA_BURP8  ;  B2T6V1, CCA_BURPP  ;
DR   Q63YC3, CCA_BURPS  ;  Q39C44, CCA_BURS3  ;  A4JIK4, CCA_BURVG  ;
DR   Q7MBF4, CCA_CHRVO  ;  A8APT7, CCA_CITK8  ;  A9KEZ9, CCA_COXBN  ;
DR   A9NAS1, CCA_COXBR  ;  Q820V9, CCA_COXBU  ;  Q0KF16, CCA_CUPNH  ;
DR   Q476S9, CCA_CUPPJ  ;  B2AGH1, CCA_CUPTR  ;  Q477X0, CCA_DECAR  ;
DR   A7ZRT7, CCA_ECO24  ;  B7UIW4, CCA_ECO27  ;  B7MAD3, CCA_ECO45  ;
DR   B7LGZ2, CCA_ECO55  ;  Q8XBL4, CCA_ECO57  ;  B5YR96, CCA_ECO5E  ;
DR   B7NJR9, CCA_ECO7I  ;  B7N0K6, CCA_ECO81  ;  B7LZK6, CCA_ECO8A  ;
DR   C4ZQX3, CCA_ECOBW  ;  B1XG61, CCA_ECODH  ;  A8A4L0, CCA_ECOHS  ;
DR   A1AFX8, CCA_ECOK1  ;  Q0TD50, CCA_ECOL5  ;  Q8CXX6, CCA_ECOL6  ;
DR   B1IRR0, CCA_ECOLC  ;  P06961, CCA_ECOLI  ;  B7ND45, CCA_ECOLU  ;
DR   B6I427, CCA_ECOSE  ;  B1LF48, CCA_ECOSM  ;  Q1R6S5, CCA_ECOUT  ;
DR   C5BHG5, CCA_EDWI9  ;  A4WEI8, CCA_ENT38  ;  Q834S5, CCA_ENTFA  ;
DR   A7MJU1, CCA_ENTS8  ;  Q6D160, CCA_ERWCT  ;  B2VGJ4, CCA_ERWT9  ;
DR   B7LQD4, CCA_ESCF3  ;  Q47907, CCA_FRANO  ;  Q14JW7, CCA_FRAT1  ;
DR   A0Q8A2, CCA_FRATN  ;  Q5NIG4, CCA_FRATT  ;  Q5KXX0, CCA_GEOKA  ;
DR   Q7SIB1, CCA_GEOSE  ;  C5D3B5, CCA_GEOSW  ;  A4IQ63, CCA_GEOTN  ;
DR   Q9L7A3, CCA_HAEDU  ;  A5UCK0, CCA_HAEIE  ;  A5UJ23, CCA_HAEIG  ;
DR   P45269, CCA_HAEIN  ;  Q2SM94, CCA_HAHCH  ;  A1WZI2, CCA_HALHL  ;
DR   B9LS95, CCA_HALLT  ;  Q5V030, CCA_HALMA  ;  B0R2Q7, CCA_HALS3  ;
DR   Q9HSP6, CCA_HALSA  ;  C4K6G4, CCA_HAMD5  ;  A4G969, CCA_HERAR  ;
DR   Q5QY23, CCA_IDILO  ;  A6T2Y3, CCA_JANMA  ;  B5XU35, CCA_KLEP3  ;
DR   A6TE35, CCA_KLEP7  ;  Q5FKF0, CCA_LACAC  ;  Q03S97, CCA_LACBA  ;
DR   Q039G0, CCA_LACC3  ;  B3WE84, CCA_LACCB  ;  Q1G9U3, CCA_LACDA  ;
DR   Q049Z4, CCA_LACDB  ;  B2GC39, CCA_LACF3  ;  Q043S5, CCA_LACGA  ;
DR   A8YV39, CCA_LACH4  ;  Q74JK7, CCA_LACJO  ;  Q9CFC2, CCA_LACLA  ;
DR   A2RJT1, CCA_LACLM  ;  Q02Y22, CCA_LACLS  ;  Q88W02, CCA_LACPL  ;
DR   A5VJK7, CCA_LACRD  ;  B2G721, CCA_LACRJ  ;  Q1WU19, CCA_LACS1  ;
DR   Q38WX5, CCA_LACSS  ;  C1DAG2, CCA_LARHH  ;  Q5X1E5, CCA_LEGPA  ;
DR   Q5ZRX9, CCA_LEGPH  ;  Q5WT58, CCA_LEGPL  ;  B1Y634, CCA_LEPCP  ;
DR   B1MYC1, CCA_LEUCK  ;  Q03Y57, CCA_LEUMM  ;  Q92AA3, CCA_LISIN  ;
DR   C1KWK5, CCA_LISMC  ;  Q71YB0, CCA_LISMF  ;  B8DC21, CCA_LISMH  ;
DR   Q8Y5Z8, CCA_LISMO  ;  A0AK10, CCA_LISW6  ;  Q65Q41, CCA_MANSM  ;
DR   A1U5G5, CCA_MARAV  ;  Q8TGX2, CCA_METAC  ;  A7I912, CCA_METB6  ;
DR   Q46AZ4, CCA_METBF  ;  Q60CQ4, CCA_METCA  ;  Q1GZ11, CCA_METFK  ;
DR   Q58511, CCA_METJA  ;  Q8TGY5, CCA_METKA  ;  A4FXY2, CCA_METM5  ;
DR   A6VFP0, CCA_METM7  ;  Q8PZM3, CCA_METMA  ;  Q6LYP1, CCA_METMP  ;
DR   O26684, CCA_METTH  ;  Q74NA6, CCA_NANEQ  ;  Q5F8K9, CCA_NEIG1  ;
DR   B4RLV5, CCA_NEIG2  ;  A9LZC1, CCA_NEIM0  ;  Q9JUB2, CCA_NEIMA  ;
DR   Q9JZ88, CCA_NEIMB  ;  A1KU50, CCA_NEIMF  ;  Q0AIP2, CCA_NITEC  ;
DR   Q82U82, CCA_NITEU  ;  Q2Y681, CCA_NITMU  ;  Q3JE31, CCA_NITOC  ;
DR   Q8EQD6, CCA_OCEIH  ;  Q9CP21, CCA_PASMU  ;  C6DDL7, CCA_PECCP  ;
DR   Q03F94, CCA_PEDPA  ;  Q7MAZ9, CCA_PHOLL  ;  Q6LV05, CCA_PHOPR  ;
DR   Q6L1N2, CCA_PICTO  ;  A1VSY7, CCA_POLNA  ;  B4EW50, CCA_PROMH  ;
DR   Q48NU4, CCA_PSE14  ;  Q15QQ0, CCA_PSEA6  ;  A6UZ87, CCA_PSEA7  ;
DR   B7V4H0, CCA_PSEA8  ;  Q02TH9, CCA_PSEAB  ;  Q9I5V3, CCA_PSEAE  ;
DR   Q1IG27, CCA_PSEE4  ;  Q4K4W8, CCA_PSEF5  ;  C3K334, CCA_PSEFS  ;
DR   A4XZK2, CCA_PSEMY  ;  A5VXI8, CCA_PSEP1  ;  Q3K5S5, CCA_PSEPF  ;
DR   B0KJ86, CCA_PSEPG  ;  Q88QU2, CCA_PSEPK  ;  B1JDY1, CCA_PSEPW  ;
DR   Q88A53, CCA_PSESM  ;  Q4ZMF8, CCA_PSEU2  ;  A1SRC9, CCA_PSYIN  ;
DR   Q9V2H1, CCA_PYRAB  ;  Q8ZTC3, CCA_PYRAE  ;  Q8TH22, CCA_PYRFU  ;
DR   O74081, CCA_PYRHO  ;  A1RS16, CCA_PYRIL  ;  Q5JJ38, CCA_PYRKO  ;
DR   Q1LS11, CCA_RALME  ;  Q8Y395, CCA_RALSO  ;  B5F6A0, CCA_SALA4  ;
DR   A9MPV9, CCA_SALAR  ;  Q57JQ5, CCA_SALCH  ;  B5FHT9, CCA_SALDC  ;
DR   B5QZ40, CCA_SALEP  ;  B5REG2, CCA_SALG2  ;  B4TI55, CCA_SALHS  ;
DR   B4T674, CCA_SALNS  ;  Q5PC82, CCA_SALPA  ;  A9N5Y2, CCA_SALPB  ;
DR   C0PYX7, CCA_SALPC  ;  B5BG15, CCA_SALPK  ;  B4TVT8, CCA_SALSV  ;
DR   Q8Z3M9, CCA_SALTI  ;  Q8ZLY4, CCA_SALTY  ;  A8GJU7, CCA_SERP5  ;
DR   B8EBU8, CCA_SHEB2  ;  A3D1R1, CCA_SHEB5  ;  A6WKL1, CCA_SHEB8  ;
DR   A9L5J0, CCA_SHEB9  ;  Q12KC4, CCA_SHEDO  ;  Q07YU1, CCA_SHEFN  ;
DR   A3QBN1, CCA_SHELP  ;  A8H161, CCA_SHEPA  ;  B8CJF9, CCA_SHEPW  ;
DR   A0KZT1, CCA_SHESA  ;  A8FS72, CCA_SHESH  ;  Q0HG49, CCA_SHESM  ;
DR   Q0HSE2, CCA_SHESR  ;  B1KHF1, CCA_SHEWM  ;  B2U1G0, CCA_SHIB3  ;
DR   Q31WX9, CCA_SHIBS  ;  Q32BQ8, CCA_SHIDS  ;  Q0T0K7, CCA_SHIF8  ;
DR   Q821A6, CCA_SHIFL  ;  Q3YXI6, CCA_SHISS  ;  Q2NWE2, CCA_SODGM  ;
DR   A7X2F4, CCA_STAA1  ;  Q2YY49, CCA_STAAB  ;  Q5HFW6, CCA_STAAC  ;
DR   A6QH08, CCA_STAAE  ;  Q99U32, CCA_STAAM  ;  Q7A5K2, CCA_STAAN  ;
DR   Q6GGV2, CCA_STAAR  ;  Q6G9A5, CCA_STAAS  ;  A8Z437, CCA_STAAT  ;
DR   Q8NWP0, CCA_STAAW  ;  B9DNX1, CCA_STACT  ;  Q5HP86, CCA_STAEQ  ;
DR   Q8CP70, CCA_STAES  ;  Q4L6G1, CCA_STAHJ  ;  Q49XR3, CCA_STAS1  ;
DR   Q8E4J0, CCA_STRA3  ;  Q8DYY1, CCA_STRA5  ;  A8AX96, CCA_STRGC  ;
DR   B4SIY9, CCA_STRM5  ;  B2FUP5, CCA_STRMK  ;  Q8DUL8, CCA_STRMU  ;
DR   Q9A0A5, CCA_STRP1  ;  P0DA18, CCA_STRP3  ;  B5E6J9, CCA_STRP4  ;
DR   Q5XCN7, CCA_STRP6  ;  Q8P1E3, CCA_STRP8  ;  Q1JCB2, CCA_STRPB  ;
DR   Q1JM96, CCA_STRPC  ;  Q1JHE0, CCA_STRPD  ;  Q1J760, CCA_STRPF  ;
DR   A2RF34, CCA_STRPG  ;  Q48U40, CCA_STRPM  ;  Q97PP9, CCA_STRPN  ;
DR   P0DA19, CCA_STRPQ  ;  B2IR74, CCA_STRPS  ;  Q8CWQ3, CCA_STRR6  ;
DR   A4W0U8, CCA_STRS2  ;  A3CMU4, CCA_STRSV  ;  A4VUK6, CCA_STRSY  ;
DR   Q5M153, CCA_STRT1  ;  Q5M5P1, CCA_STRT2  ;  Q03M28, CCA_STRTD  ;
DR   B9DRX9, CCA_STRU0  ;  Q4J9A0, CCA_SULAC  ;  C3N558, CCA_SULIA  ;
DR   C4KGR1, CCA_SULIK  ;  C3MPH6, CCA_SULIL  ;  C3MYG4, CCA_SULIM  ;
DR   C3NHZ5, CCA_SULIN  ;  C3NDQ6, CCA_SULIY  ;  P77978, CCA_SULSH  ;
DR   Q97Z92, CCA_SULSO  ;  Q973E7, CCA_SULTO  ;  C5BPQ5, CCA_TERTT  ;
DR   Q9HI95, CCA_THEAC  ;  Q9V302, CCA_THEAI  ;  C5A3V9, CCA_THEGJ  ;
DR   B1Y9T4, CCA_THENV  ;  Q97CI4, CCA_THEVO  ;  Q31J37, CCA_THICR  ;
DR   B8GUR8, CCA_THISH  ;  C4LB55, CCA_TOLAT  ;  C5CNM3, CCA_VARPS  ;
DR   A1WHX2, CCA_VEREI  ;  A5F5I2, CCA_VIBC3  ;  Q9KPC6, CCA_VIBCH  ;
DR   C3LQY9, CCA_VIBCM  ;  Q5E2K7, CCA_VIBF1  ;  B5FB77, CCA_VIBFM  ;
DR   A7MWN9, CCA_VIBHB  ;  Q87SK9, CCA_VIBPA  ;  Q8CWL6, CCA_VIBVU  ;
DR   Q7M7K5, CCA_VIBVY  ;  Q8D2W4, CCA_WIGBR  ;  Q8PPG9, CCA_XANAC  ;
DR   Q3BXK9, CCA_XANC5  ;  Q4UYN8, CCA_XANC8  ;  B0RNU6, CCA_XANCB  ;
DR   Q8P5D4, CCA_XANCP  ;  Q2NZ41, CCA_XANOM  ;  B2I9I0, CCA_XYLF2  ;
DR   Q9PDL7, CCA_XYLFA  ;  B0U6J4, CCA_XYLFM  ;  Q87DS9, CCA_XYLFT  ;
DR   A1JQW2, CCA_YERE8  ;  A7FE75, CCA_YERP3  ;  Q1C370, CCA_YERPA  ;
DR   B2K2H9, CCA_YERPB  ;  Q8ZI64, CCA_YERPE  ;  A9R7D9, CCA_YERPG  ;
DR   Q1CMD8, CCA_YERPN  ;  A4THT5, CCA_YERPP  ;  Q665U9, CCA_YERPS  ;
DR   B1JM22, CCA_YERPY  ;  Q96Q11, TRNT1_HUMAN;  Q8K1J6, TRNT1_MOUSE;
//
ID   2.7.7.73
DE   Sulfur carrier protein ThiS adenylyltransferase.
CA   ATP + [ThiS] = diphosphate + adenylyl-[ThiS].
CF   Zinc.
CC   -!- The enzyme catalyzes the adenylation of ThiS, a sulfur carrier
CC       protein involved in the biosynthesis of thiamine.
CC   -!- The enzyme shows significant structural similarity to ubiquitin-
CC       activating enzyme.
CC   -!- In Escherichia coli, but not in Bacillus subtilis, the enzyme forms a
CC       cross link from Cys-184 to the ThiS carboxy terminus (the position
CC       that is also thiolated) via an acyldisulfide.
CC   -!- Formerly EC 2.7.7.n3.
DR   O31619, THIF_BACSU ;  P30138, THIF_ECOLI ;
//
ID   2.7.7.n1
DE   Adenosine monophosphate-protein transferase.
CA   ATP + [protein] = diphosphate + [protein]-AMP.
DR   Q17A75, FICD_AEDAE ;  A8X181, FICD_CAEBR ;  Q23544, FICD_CAEEL ;
DR   B0W429, FICD_CULQU ;  Q6ZM51, FICD_DANRE ;  B3MK83, FICD_DROAN ;
DR   B3N5J3, FICD_DROER ;  B4JBN5, FICD_DROGR ;  Q8SWV6, FICD_DROME ;
DR   B4KFW6, FICD_DROMO ;  B4GJC1, FICD_DROPE ;  Q29JP8, FICD_DROPS ;
DR   B4I1V5, FICD_DROSE ;  B4Q4M7, FICD_DROSI ;  B4LQT7, FICD_DROVI ;
DR   B4MUQ2, FICD_DROWI ;  B4P0E1, FICD_DROYA ;  Q9BVA6, FICD_HUMAN ;
DR   Q8BIX9, FICD_MOUSE ;  A7SVT1, FICD_NEMVE ;  Q6AY47, FICD_RAT   ;
DR   B4F6I5, FICD_XENTR ;  P20605, FIC_ECOLI  ;  P20751, FIC_SALTY  ;
DR   Q06277, IBPA_HAES2 ;  Q87P32, VOPS_VIBPA ;  P55548, Y4LH_RHISN ;
DR   P44088, Y977_HAEIN ;  O66426, YZ38_AQUAE ;
//
ID   2.7.7.n2
DE   Transferred entry: 2.7.7.67.
//
ID   2.7.7.n3
DE   Transferred entry: 2.7.7.73.
//
ID   2.7.8.1
DE   Ethanolaminephosphotransferase.
CA   CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine.
PR   PROSITE; PDOC00321;
DR   Q5ZKD1, CEPT1_CHICK;  Q9Y6K0, CEPT1_HUMAN;  Q8BGS7, CEPT1_MOUSE;
DR   Q6AXM5, CEPT1_RAT  ;  Q7ZYQ3, CEPT1_XENLA;  Q28H54, CEPT1_XENTR;
DR   Q17QM4, EPT1_BOVIN ;  Q9C0D9, EPT1_HUMAN ;  Q80TA1, EPT1_MOUSE ;
DR   Q5NV96, EPT1_PONAB ;  P22140, EPT1_YEAST ;
//
ID   2.7.8.2
DE   Diacylglycerol cholinephosphotransferase.
AN   1-alkyl-2-acetylglycerol cholinephosphotransferase.
AN   Alkylacylglycerol cholinephosphotransferase.
AN   Cholinephosphotransferase.
AN   Phosphorylcholine--glyceride transferase.
CA   CDP-choline + 1,2-diacylglycerol = CMP + a phosphatidylcholine.
CC   -!- 1-alkyl-2-acylglycerol can act as acceptor.
CC   -!- Formerly EC 2.7.8.16.
PR   PROSITE; PDOC00321;
DR   Q5ZKD1, CEPT1_CHICK;  Q9Y6K0, CEPT1_HUMAN;  Q8BGS7, CEPT1_MOUSE;
DR   Q6AXM5, CEPT1_RAT  ;  Q7ZYQ3, CEPT1_XENLA;  Q28H54, CEPT1_XENTR;
DR   Q1LZE6, CHPT1_BOVIN;  Q5ZHQ5, CHPT1_CHICK;  Q7ZW02, CHPT1_DANRE;
DR   Q8WUD6, CHPT1_HUMAN;  Q8C025, CHPT1_MOUSE;  Q66H21, CHPT1_RAT  ;
DR   Q4KLV1, CHPT1_XENLA;  P17898, CPT1_YEAST ;  P22140, EPT1_YEAST ;
//
ID   2.7.8.3
DE   Ceramide cholinephosphotransferase.
CA   CDP-choline + N-acylsphingosine = CMP + sphingomyelin.
//
ID   2.7.8.4
DE   Serine-phosphoethanolamine synthase.
CA   CDP-ethanolamine + L-serine = CMP + L-serine-phosphoethanolamine.
//
ID   2.7.8.5
DE   CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase.
AN   3-phosphatidyl-1'-glycerol-3'-phosphate synthase.
AN   Glycerophosphate phosphatidyltransferase.
AN   PGP synthase.
AN   Phosphatidylglycerophosphate synthase.
CA   CDP-diacylglycerol + sn-glycerol 3-phosphate = CMP +
CA   3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate.
PR   PROSITE; PDOC00321;
DR   Q2KJ28, PGPS1_BOVIN;  Q5ZHN9, PGPS1_CHICK;  Q9Z2Z7, PGPS1_CRIGR;
DR   Q7KWX2, PGPS1_DICDI;  Q32NB8, PGPS1_HUMAN;  Q8BHF7, PGPS1_MOUSE;
DR   Q5R8K7, PGPS1_PONAB;  P79001, PGPS1_SACPS;  Q9HDW1, PGPS1_SCHPO;
DR   P25578, PGPS1_YEAST;  P63753, PGSA1_MYCTU;  O33288, PGSA2_MYCTU;
DR   O67908, PGSA_AQUAE ;  P46322, PGSA_BACSU ;  Q7VR12, PGSA_BLOFL ;
DR   Q492P7, PGSA_BLOPB ;  P0ABG0, PGSA_ECO57 ;  A1AC64, PGSA_ECOK1 ;
DR   Q0TGS6, PGSA_ECOL5 ;  P0ABF9, PGSA_ECOL6 ;  P0ABF8, PGSA_ECOLI ;
DR   Q1RAM8, PGSA_ECOUT ;  Q6D364, PGSA_ERWCT ;  P44528, PGSA_HAEIN ;
DR   P63754, PGSA_MYCBO ;  P47360, PGSA_MYCGE ;  P75520, PGSA_MYCPN ;
DR   Q7N5C8, PGSA_PHOLL ;  P45419, PGSA_PSEFL ;  Q3IYX7, PGSA_RHOS4 ;
DR   Q1RKM3, PGSA_RICBR ;  Q92JJ2, PGSA_RICCN ;  Q4UN77, PGSA_RICFE ;
DR   Q9ZE96, PGSA_RICPR ;  Q68XS5, PGSA_RICTY ;  Q57N57, PGSA_SALCH ;
DR   Q5PI18, PGSA_SALPA ;  Q8XFD0, PGSA_SALTI ;  Q7CQB9, PGSA_SALTY ;
DR   Q322L9, PGSA_SHIBS ;  Q32HD9, PGSA_SHIDS ;  Q0T3L5, PGSA_SHIF8 ;
DR   Q83R47, PGSA_SHIFL ;  Q3Z2T6, PGSA_SHISS ;  Q2NTS8, PGSA_SODGM ;
DR   Q5HGE8, PGSA_STAAC ;  P63755, PGSA_STAAM ;  P63756, PGSA_STAAN ;
DR   Q6GHF2, PGSA_STAAR ;  Q6G9T0, PGSA_STAAS ;  P63757, PGSA_STAAW ;
DR   Q5HPQ8, PGSA_STAEQ ;  Q8CPF7, PGSA_STAES ;  O66076, PGSA_TREPA ;
DR   Q8D2N9, PGSA_WIGBR ;  A1JLU9, PGSA_YERE8 ;  Q1C8L0, PGSA_YERPA ;
DR   Q8ZF51, PGSA_YERPE ;  Q1CHE5, PGSA_YERPN ;  A4TK40, PGSA_YERPP ;
DR   Q66BN4, PGSA_YERPS ;
//
ID   2.7.8.6
DE   Undecaprenyl-phosphate galactose phosphotransferase.
AN   Poly(isoprenol)-phosphate galactosephosphotransferase.
CA   UDP-galactose + undecaprenyl phosphate = UMP + alpha-D-galactosyl-
CA   diphosphoundecaprenol.
DR   P26406, RFBP_SALTY ;
//
ID   2.7.8.7
DE   Holo-[acyl-carrier-protein] synthase.
AN   4'-phosphopantetheinyl transferase.
AN   ACPS.
AN   Acyl carrier protein holoprotein (holo-ACP) synthetase.
AN   Acyl carrier protein synthase.
AN   Acyl carrier protein synthetase.
AN   Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl
AN   transferase.
AN   Holo-ACP synthase.
AN   Holo-ACP synthetase.
AN   Holosynthase.
AN   L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl
AN   transferase.
AN   P-pant transferase.
AN   PPTase.
CA   CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] = adenosine
CA   3',5'-bisphosphate + holo-[acyl-carrier-protein].
CF   Magnesium.
CC   -!- All polyketide synthases, fatty-acid synthases and non-ribosomal
CC       peptide synthases require post-translational modification of their
CC       constituent acyl-carrier-protein (ACP) domains to become
CC       catalytically active.
CC   -!- The inactive apo-proteins are converted into their active holo-forms
CC       by transfer of the 4'-phosphopantetheinyl moiety of CoA to the
CC       sidechain hydroxy group of a conserved serine residue in each ACP
CC       domain.
CC   -!- The enzyme from human can activate both the ACP domain of the human
CC       cytosolic multifunctional fatty acid synthase and that associated
CC       with human mitochondria as well as peptidyl-carrier and acyl-carrier-
CC       proteins from prokaryotes.
CC   -!- Removal of the 4-phosphopantetheinyl moiety from holo-ACP is carried
CC       out by EC 3.1.4.14.
DR   Q8XAN7, ACPS2_ECO57;  A9NHV3, ACPS_ACHLI ;  Q1IHY2, ACPS_ACIBL ;
DR   A5FVX4, ACPS_ACICJ ;  B9MDP1, ACPS_ACIET ;  B7J9K5, ACPS_ACIF2 ;
DR   B5EQL7, ACPS_ACIF5 ;  A1WAW0, ACPS_ACISJ ;  B9JC71, ACPS_AGRRK ;
DR   Q8UGK4, ACPS_AGRT5 ;  Q0A8Y7, ACPS_ALHEH ;  B6EKM5, ACPS_ALISL ;
DR   A6TVL0, ACPS_ALKMQ ;  A8MJ27, ACPS_ALKOO ;  B4RXM9, ACPS_ALTMD ;
DR   B8JBG5, ACPS_ANAD2 ;  Q2IHZ3, ACPS_ANADE ;  A7HCT8, ACPS_ANADF ;
DR   B9KIC8, ACPS_ANAMF ;  Q5PAZ6, ACPS_ANAMM ;  Q2GK71, ACPS_ANAPZ ;
DR   B4UEM2, ACPS_ANASK ;  B9MKY6, ACPS_ANATD ;  B7GIY1, ACPS_ANOFW ;
DR   O66995, ACPS_AQUAE ;  A8ERC0, ACPS_ARCB4 ;  Q5P082, ACPS_AROAE ;
DR   A1R8P6, ACPS_ARTAT ;  B8HCG9, ACPS_ARTCA ;  A0JZ20, ACPS_ARTS2 ;
DR   A8I3B0, ACPS_AZOC5 ;  A1K608, ACPS_AZOSB ;  A7Z1L9, ACPS_BACA2 ;
DR   C3PAT6, ACPS_BACAA ;  C3LK79, ACPS_BACAC ;  A0R8U9, ACPS_BACAH ;
DR   Q81JG3, ACPS_BACAN ;  B7JLE6, ACPS_BACC0 ;  Q73ET8, ACPS_BACC1 ;
DR   B7IU30, ACPS_BACC2 ;  C1EU95, ACPS_BACC3 ;  B7H4P0, ACPS_BACC4 ;
DR   B7HRY9, ACPS_BACC7 ;  A7GKE4, ACPS_BACCN ;  B9J0N5, ACPS_BACCQ ;
DR   Q81IT7, ACPS_BACCR ;  Q63GX2, ACPS_BACCZ ;  Q9KFG1, ACPS_BACHD ;
DR   Q6HPE3, ACPS_BACHK ;  A8FA63, ACPS_BACP2 ;  Q5WJW1, ACPS_BACSK ;
DR   P96618, ACPS_BACSU ;  A9VQF0, ACPS_BACWK ;  A1US34, ACPS_BARBK ;
DR   Q6G461, ACPS_BARHE ;  Q6G084, ACPS_BARQU ;  A9IRM3, ACPS_BART1 ;
DR   Q1LTI6, ACPS_BAUCH ;  B2II98, ACPS_BEII9 ;  C5BZZ8, ACPS_BEUC1 ;
DR   B8DVV4, ACPS_BIFA0 ;  A1A005, ACPS_BIFAA ;  Q7VRR2, ACPS_BLOFL ;
DR   Q492D3, ACPS_BLOPB ;  Q0SPF4, ACPS_BORAP ;  Q7WH64, ACPS_BORBR ;
DR   O51043, ACPS_BORBU ;  B7J0U9, ACPS_BORBZ ;  Q663A2, ACPS_BORGA ;
DR   B2S1J9, ACPS_BORHD ;  Q7W9J6, ACPS_BORPA ;  Q7VWV9, ACPS_BORPE ;
DR   A1QYG3, ACPS_BORT9 ;  O69159, ACPS_BRAJA ;  A5EKL9, ACPS_BRASB ;
DR   C0ZK19, ACPS_BREBN ;  B2SAD7, ACPS_BRUA1 ;  Q2YN04, ACPS_BRUA2 ;
DR   Q57E83, ACPS_BRUAB ;  A9MA33, ACPS_BRUC2 ;  C0RI01, ACPS_BRUMB ;
DR   P63464, ACPS_BRUME ;  A5VPJ6, ACPS_BRUO2 ;  B0CKY5, ACPS_BRUSI ;
DR   P63465, ACPS_BRUSU ;  B8D949, ACPS_BUCA5 ;  P57344, ACPS_BUCAI ;
DR   Q8K9R3, ACPS_BUCAP ;  B8D7F3, ACPS_BUCAT ;  P59475, ACPS_BUCBP ;
DR   Q057R6, ACPS_BUCCC ;  B1YVM8, ACPS_BURA4 ;  Q1BXT7, ACPS_BURCA ;
DR   B1JYB7, ACPS_BURCC ;  A0K5W3, ACPS_BURCH ;  Q0BH00, ACPS_BURCM ;
DR   A9ADD4, ACPS_BURM1 ;  A3MM38, ACPS_BURM7 ;  A2S9Z9, ACPS_BURM9 ;
DR   Q62LS6, ACPS_BURMA ;  A1V6B3, ACPS_BURMS ;  A3NXL2, ACPS_BURP0 ;
DR   A3NBS5, ACPS_BURP6 ;  B2JFK6, ACPS_BURP8 ;  B2SZV1, ACPS_BURPP ;
DR   Q63S99, ACPS_BURPS ;  Q39I69, ACPS_BURS3 ;  Q2SXT0, ACPS_BURTA ;
DR   A4JCR5, ACPS_BURVG ;  A4XIB7, ACPS_CALS8 ;  A7ZDS5, ACPS_CAMC1 ;
DR   A7GY16, ACPS_CAMC5 ;  A0RPF9, ACPS_CAMFF ;  A7I379, ACPS_CAMHC ;
DR   A8FN84, ACPS_CAMJ8 ;  A7H5D0, ACPS_CAMJD ;  Q9PMP8, ACPS_CAMJE ;
DR   A1W123, ACPS_CAMJJ ;  Q5HT08, ACPS_CAMJR ;  B9KEZ8, ACPS_CAMLR ;
DR   Q3AEB5, ACPS_CARHZ ;  B8H624, ACPS_CAUCN ;  Q9A807, ACPS_CAUCR ;
DR   B0T3H7, ACPS_CAUSK ;  A9WE63, ACPS_CHLAA ;  Q5L623, ACPS_CHLAB ;
DR   B8G840, ACPS_CHLAD ;  Q3AU14, ACPS_CHLCH ;  Q820E7, ACPS_CHLCV ;
DR   Q254H8, ACPS_CHLFF ;  B3EGP9, ACPS_CHLL2 ;  Q9PKT6, ACPS_CHLMU ;
DR   B3QR46, ACPS_CHLP8 ;  Q9Z8M5, ACPS_CHLPN ;  B9LIY4, ACPS_CHLSY ;
DR   B0B9K8, ACPS_CHLT2 ;  B3QTH9, ACPS_CHLT3 ;  Q3KMS0, ACPS_CHLTA ;
DR   B0BB87, ACPS_CHLTB ;  Q8KB56, ACPS_CHLTE ;  O84102, ACPS_CHLTR ;
DR   Q7NWB8, ACPS_CHRVO ;  A8AD21, ACPS_CITK8 ;  A5CU72, ACPS_CLAM3 ;
DR   B0RD39, ACPS_CLAMS ;  Q97LR5, ACPS_CLOAB ;  A6M302, ACPS_CLOB8 ;
DR   B2V003, ACPS_CLOBA ;  B2TQY6, ACPS_CLOBB ;  B8I3U1, ACPS_CLOCE ;
DR   A5N379, ACPS_CLOK5 ;  A0PY92, ACPS_CLONN ;  Q0TUE3, ACPS_CLOP1 ;
DR   Q8XNP1, ACPS_CLOPE ;  A9KLF9, ACPS_CLOPH ;  Q0SW89, ACPS_CLOPS ;
DR   Q890W8, ACPS_CLOTE ;  B5Y8E2, ACPS_COPPD ;  Q8FMW0, ACPS_COREF ;
DR   A4QGP6, ACPS_CORGB ;  Q8NMS4, ACPS_CORGL ;  Q0K8N7, ACPS_CUPNH ;
DR   Q46Z22, ACPS_CUPPJ ;  B3R1Z5, ACPS_CUPTR ;  Q11T75, ACPS_CYTH3 ;
DR   Q47EF3, ACPS_DECAR ;  Q3Z9B0, ACPS_DEHE1 ;  A5FS12, ACPS_DEHSB ;
DR   Q3ZZK3, ACPS_DEHSC ;  C1D023, ACPS_DEIDV ;  Q9RXR0, ACPS_DEIRA ;
DR   A9BNJ1, ACPS_DELAS ;  C6BV78, ACPS_DESAD ;  B1I1U5, ACPS_DESAP ;
DR   B8IZX1, ACPS_DESDA ;  Q30ZQ5, ACPS_DESDG ;  C4XGU1, ACPS_DESMR ;
DR   A4J8G9, ACPS_DESRM ;  Q72AT2, ACPS_DESVH ;  B8DPF0, ACPS_DESVM ;
DR   A1VCV8, ACPS_DESVV ;  A8LLD7, ACPS_DINSH ;  A7ZQ07, ACPS_ECO24 ;
DR   B7UH03, ACPS_ECO27 ;  B7MIP8, ACPS_ECO45 ;  B7LDF6, ACPS_ECO55 ;
DR   Q8XA39, ACPS_ECO57 ;  B7NRL6, ACPS_ECO7I ;  B7MYJ4, ACPS_ECO81 ;
DR   B7M8H6, ACPS_ECO8A ;  C4ZYI6, ACPS_ECOBW ;  A8A373, ACPS_ECOHS ;
DR   A1AE93, ACPS_ECOK1 ;  Q0TES5, ACPS_ECOL5 ;  Q8FF19, ACPS_ECOL6 ;
DR   B1IVR4, ACPS_ECOLC ;  P24224, ACPS_ECOLI ;  B7N6F1, ACPS_ECOLU ;
DR   B6I5D7, ACPS_ECOSE ;  B1LP76, ACPS_ECOSM ;  Q1R8H0, ACPS_ECOUT ;
DR   C5B8X8, ACPS_EDWI9 ;  Q3YSD5, ACPS_EHRCJ ;  Q2GG91, ACPS_EHRCR ;
DR   Q5FHL6, ACPS_EHRRG ;  Q5HBI7, ACPS_EHRRW ;  A4WDD4, ACPS_ENT38 ;
DR   Q820V0, ACPS_ENTFA ;  A7MH03, ACPS_ENTS8 ;  Q6D222, ACPS_ERWCT ;
DR   B2VEA7, ACPS_ERWT9 ;  Q2NCF7, ACPS_ERYLH ;  B7LV01, ACPS_ESCF3 ;
DR   B1YF32, ACPS_EXIS2 ;  C4L132, ACPS_EXISA ;  B0S2M4, ACPS_FINM2 ;
DR   Q0RRN3, ACPS_FRAAA ;  Q2JFD8, ACPS_FRASC ;  Q8RDZ7, ACPS_FUSNN ;
DR   B5EI15, ACPS_GEOBB ;  Q5L3G7, ACPS_GEOKA ;  B3E694, ACPS_GEOLS ;
DR   Q39UG1, ACPS_GEOMG ;  B9M2U0, ACPS_GEOSF ;  Q74C71, ACPS_GEOSL ;
DR   C6E2U2, ACPS_GEOSM ;  C5D4D1, ACPS_GEOSW ;  A4IJT3, ACPS_GEOTN ;
DR   Q7NE72, ACPS_GLOVI ;  Q5FPZ9, ACPS_GLUOX ;  Q0BTG4, ACPS_GRABC ;
DR   A1WT13, ACPS_HALHL ;  B8D0V9, ACPS_HALOH ;  C4K8H4, ACPS_HAMD5 ;
DR   Q17XL2, ACPS_HELAH ;  B6JM38, ACPS_HELP2 ;  B5Z7H0, ACPS_HELPG ;
DR   Q1CT62, ACPS_HELPH ;  Q9ZL36, ACPS_HELPJ ;  O25488, ACPS_HELPY ;
DR   A9B2B6, ACPS_HERA2 ;  A4G6R4, ACPS_HERAR ;  B4U7U7, ACPS_HYDS0 ;
DR   Q0C3U0, ACPS_HYPNA ;  Q5R110, ACPS_IDILO ;  A6SXR7, ACPS_JANMA ;
DR   Q28V25, ACPS_JANSC ;  A6W5X5, ACPS_KINRD ;  B5XNH4, ACPS_KLEP3 ;
DR   A6TCH7, ACPS_KLEP7 ;  B2GJ30, ACPS_KOCRD ;  Q5FMB3, ACPS_LACAC ;
DR   Q03T07, ACPS_LACBA ;  Q034T8, ACPS_LACC3 ;  B3WAR1, ACPS_LACCB ;
DR   Q1GBP7, ACPS_LACDA ;  Q04C46, ACPS_LACDB ;  B2GA64, ACPS_LACF3 ;
DR   A8YXI2, ACPS_LACH4 ;  Q74LB3, ACPS_LACJO ;  Q9CH95, ACPS_LACLA ;
DR   A2RLV5, ACPS_LACLM ;  Q030B5, ACPS_LACLS ;  Q88Z44, ACPS_LACPL ;
DR   A5VI50, ACPS_LACRD ;  Q9FCV3, ACPS_LACRE ;  B2G5M8, ACPS_LACRJ ;
DR   Q1WV15, ACPS_LACS1 ;  Q38V63, ACPS_LACSS ;  C1D7L8, ACPS_LARHH ;
DR   Q6AD33, ACPS_LEIXX ;  B0SE17, ACPS_LEPBA ;  Q04U76, ACPS_LEPBJ ;
DR   Q053N9, ACPS_LEPBL ;  B0SM94, ACPS_LEPBP ;  B1XZM3, ACPS_LEPCP ;
DR   Q72U18, ACPS_LEPIC ;  Q8F136, ACPS_LEPIN ;  B1MX05, ACPS_LEUCK ;
DR   Q03V72, ACPS_LEUMM ;  Q92DD0, ACPS_LISIN ;  C1L1F5, ACPS_LISMC ;
DR   Q721T0, ACPS_LISMF ;  B8DG74, ACPS_LISMH ;  Q8Y8L2, ACPS_LISMO ;
DR   A0AH03, ACPS_LISW6 ;  B9E8C4, ACPS_MACCJ ;  Q2W515, ACPS_MAGSA ;
DR   A0L8S4, ACPS_MAGSM ;  Q0APC3, ACPS_MARMM ;  A6VUP9, ACPS_MARMS ;
DR   Q11JT0, ACPS_MESSB ;  B7L2A4, ACPS_METC4 ;  A9W511, ACPS_METEP ;
DR   B8IMY6, ACPS_METNO ;  B1Z872, ACPS_METPB ;  A2SDH7, ACPS_METPP ;
DR   B1LTR5, ACPS_METRJ ;  B0UE20, ACPS_METS4 ;  B8EK15, ACPS_METSB ;
DR   C5CC21, ACPS_MICLC ;  Q2RGI1, ACPS_MOOTA ;  P0A4W9, ACPS_MYCBO ;
DR   A1KLL9, ACPS_MYCBP ;  C1AEZ0, ACPS_MYCBT ;  Q2SS83, ACPS_MYCCT ;
DR   Q7NB74, ACPS_MYCGA ;  Q9ZB79, ACPS_MYCGE ;  B8ZR72, ACPS_MYCLB ;
DR   Q9X7E3, ACPS_MYCLE ;  B2HPL7, ACPS_MYCMM ;  Q6KHG5, ACPS_MYCMO ;
DR   Q6MT35, ACPS_MYCMS ;  Q73XH8, ACPS_MYCPA ;  P75480, ACPS_MYCPN ;
DR   Q98R97, ACPS_MYCPU ;  A0R1H6, ACPS_MYCS2 ;  A3Q2R0, ACPS_MYCSJ ;
DR   A1UJA6, ACPS_MYCSK ;  Q1B5T0, ACPS_MYCSS ;  A5U5M1, ACPS_MYCTA ;
DR   P0A4W8, ACPS_MYCTU ;  A0PU93, ACPS_MYCUA ;  Q1D4A0, ACPS_MYXXD ;
DR   B2A4X6, ACPS_NATTJ ;  B9L9S0, ACPS_NAUPA ;  Q5F6P2, ACPS_NEIG1 ;
DR   B4RQ92, ACPS_NEIG2 ;  A9M273, ACPS_NEIM0 ;  Q9RQW2, ACPS_NEIMA ;
DR   P0A0Q5, ACPS_NEIMB ;  P0A0Q6, ACPS_NEIMC ;  A1KVH5, ACPS_NEIMF ;
DR   Q0AF73, ACPS_NITEC ;  Q820I1, ACPS_NITEU ;  Q1QL52, ACPS_NITHX ;
DR   Q2Y864, ACPS_NITMU ;  Q3JCY7, ACPS_NITOC ;  A6Q3W1, ACPS_NITSB ;
DR   Q3SRB1, ACPS_NITWN ;  Q5Z0D8, ACPS_NOCFA ;  A1SF35, ACPS_NOCSJ ;
DR   Q8ESK9, ACPS_OCEIH ;  Q04DI0, ACPS_OENOB ;  B6JGF9, ACPS_OLICO ;
DR   Q6YQD4, ACPS_ONYPE ;  A5CDM0, ACPS_ORITB ;  B3CQ27, ACPS_ORITI ;
DR   A1AZ41, ACPS_PARDP ;  A7HX46, ACPS_PARL1 ;  Q6MAG4, ACPS_PARUW ;
DR   C6DBM7, ACPS_PECCP ;  Q03DZ1, ACPS_PEDPA ;  Q3A5V3, ACPS_PELCD ;
DR   Q3B672, ACPS_PELLD ;  B4SFE8, ACPS_PELPB ;  A1AR95, ACPS_PELPD ;
DR   Q4FLS7, ACPS_PELUB ;  A9BJX6, ACPS_PETMO ;  B4RCU9, ACPS_PHEZH ;
DR   Q7N1X9, ACPS_PHOLL ;  Q6LMS5, ACPS_PHOPR ;  A1VRS8, ACPS_POLNA ;
DR   B1XTL7, ACPS_POLNS ;  Q126K7, ACPS_POLSJ ;  A4SVW6, ACPS_POLSQ ;
DR   Q6A6U0, ACPS_PROAC ;  A4SCZ9, ACPS_PROVI ;  Q15PH8, ACPS_PSEA6 ;
DR   Q1LKN5, ACPS_RALME ;  Q8Y0H7, ACPS_RALSO ;  A9WMF1, ACPS_RENSM ;
DR   B3PUN6, ACPS_RHIE6 ;  Q2KAE5, ACPS_RHIEC ;  Q1MJ56, ACPS_RHIL3 ;
DR   Q985A8, ACPS_RHILO ;  B5ZW71, ACPS_RHILW ;  Q92R49, ACPS_RHIME ;
DR   C3M8S2, ACPS_RHISN ;  Q7UQA5, ACPS_RHOBA ;  B6IN03, ACPS_RHOCS ;
DR   Q21XM1, ACPS_RHOFD ;  Q2IWU7, ACPS_RHOP2 ;  Q07M73, ACPS_RHOP5 ;
DR   Q6N6C3, ACPS_RHOPA ;  Q214J8, ACPS_RHOPB ;  Q136W1, ACPS_RHOPS ;
DR   B3QJH2, ACPS_RHOPT ;  A3PGF6, ACPS_RHOS1 ;  Q3J5W3, ACPS_RHOS4 ;
DR   A4WVP7, ACPS_RHOS5 ;  B9KSA5, ACPS_RHOSK ;  C3PP12, ACPS_RICAE ;
DR   A8GP44, ACPS_RICAH ;  A8GW65, ACPS_RICB8 ;  Q1RHU1, ACPS_RICBR ;
DR   A8EYA8, ACPS_RICCK ;  Q92H90, ACPS_RICCN ;  Q4UKX9, ACPS_RICFE ;
DR   A8F257, ACPS_RICM5 ;  Q9ZCX5, ACPS_RICPR ;  C4K1J2, ACPS_RICPU ;
DR   B0BYC4, ACPS_RICRO ;  A8GSU8, ACPS_RICRS ;  Q68WF9, ACPS_RICTY ;
DR   A7NPN5, ACPS_ROSCS ;  Q16AI8, ACPS_ROSDO ;  A5US51, ACPS_ROSS1 ;
DR   A1AWQ3, ACPS_RUTMC ;  A4FPF7, ACPS_SACEN ;  B5F1F7, ACPS_SALA4 ;
DR   A8M4B5, ACPS_SALAI ;  A9MGY0, ACPS_SALAR ;  Q57LD4, ACPS_SALCH ;
DR   B5FRC1, ACPS_SALDC ;  B5QTU4, ACPS_SALEP ;  B5RD45, ACPS_SALG2 ;
DR   B4TE11, ACPS_SALHS ;  B4T1F4, ACPS_SALNS ;  Q5PIJ4, ACPS_SALPA ;
DR   A9N1T5, ACPS_SALPB ;  C0PYH1, ACPS_SALPC ;  B5BAT4, ACPS_SALPK ;
DR   B4TS10, ACPS_SALSV ;  P63467, ACPS_SALTI ;  A4XBI2, ACPS_SALTO ;
DR   P63466, ACPS_SALTY ;  A8GI21, ACPS_SERP5 ;  A1S3Y5, ACPS_SHEAM ;
DR   B8EBP8, ACPS_SHEB2 ;  A3D1W0, ACPS_SHEB5 ;  A6WKR1, ACPS_SHEB8 ;
DR   A9L5P0, ACPS_SHEB9 ;  Q12KI5, ACPS_SHEDO ;  Q07Z00, ACPS_SHEFN ;
DR   B0TIW1, ACPS_SHEHH ;  A3QBT1, ACPS_SHELP ;  Q8EH77, ACPS_SHEON ;
DR   A8H1D1, ACPS_SHEPA ;  A4Y4K8, ACPS_SHEPC ;  B8CQJ1, ACPS_SHEPW ;
DR   A0KZM8, ACPS_SHESA ;  A8FSE0, ACPS_SHESH ;  Q0HGA2, ACPS_SHESM ;
DR   Q0HSJ5, ACPS_SHESR ;  A1RMC3, ACPS_SHESW ;  B1KI61, ACPS_SHEWM ;
DR   B2TXX6, ACPS_SHIB3 ;  Q31XS4, ACPS_SHIBS ;  Q32CV8, ACPS_SHIDS ;
DR   Q0T1U2, ACPS_SHIF8 ;  Q83K24, ACPS_SHIFL ;  Q3YYV3, ACPS_SHISS ;
DR   Q5LNK3, ACPS_SILPO ;  Q1GDH3, ACPS_SILST ;  A6U7A6, ACPS_SINMW ;
DR   Q2NS17, ACPS_SODGM ;  Q01RT7, ACPS_SOLUE ;  Q1GT99, ACPS_SPHAL ;
DR   A5VD51, ACPS_SPHWW ;  A7X4P8, ACPS_STAA1 ;  A6U3F7, ACPS_STAA2 ;
DR   Q2FF54, ACPS_STAA3 ;  Q9ZAH6, ACPS_STAA8 ;  A5IUL7, ACPS_STAA9 ;
DR   Q2YUI2, ACPS_STAAB ;  Q5HED0, ACPS_STAAC ;  A6QIR6, ACPS_STAAE ;
DR   P63468, ACPS_STAAM ;  P63469, ACPS_STAAN ;  Q6GF02, ACPS_STAAR ;
DR   Q6G7N8, ACPS_STAAS ;  A8Z4X4, ACPS_STAAT ;  P63470, ACPS_STAAW ;
DR   B9DMJ0, ACPS_STACT ;  Q5HME4, ACPS_STAEQ ;  Q8CNK6, ACPS_STAES ;
DR   Q4L7V6, ACPS_STAHJ ;  Q49Z25, ACPS_STAS1 ;  Q3JZK4, ACPS_STRA1 ;
DR   P63471, ACPS_STRA3 ;  P63472, ACPS_STRA5 ;  Q82DL2, ACPS_STRAW ;
DR   O86785, ACPS_STRCO ;  C0M6I4, ACPS_STRE4 ;  B4U177, ACPS_STREM ;
DR   B1W3W2, ACPS_STRGG ;  Q8DSF3, ACPS_STRMU ;  Q99Y97, ACPS_STRP1 ;
DR   Q04J73, ACPS_STRP2 ;  P0CZ50, ACPS_STRP3 ;  B5E746, ACPS_STRP4 ;
DR   Q5XAA3, ACPS_STRP6 ;  C1C8T7, ACPS_STRP7 ;  P63474, ACPS_STRP8 ;
DR   Q1JA49, ACPS_STRPB ;  Q1JK99, ACPS_STRPC ;  Q1JF93, ACPS_STRPD ;
DR   Q1J544, ACPS_STRPF ;  A2RCT2, ACPS_STRPG ;  B1I756, ACPS_STRPI ;
DR   B8ZMG2, ACPS_STRPJ ;  Q48RM7, ACPS_STRPM ;  P0A2W6, ACPS_STRPN ;
DR   P0CZ51, ACPS_STRPQ ;  B5XI22, ACPS_STRPZ ;  P0A2W7, ACPS_STRR6 ;
DR   A4W3N6, ACPS_STRS2 ;  C0MEB8, ACPS_STRS7 ;  A3CLD6, ACPS_STRSV ;
DR   A4VXE0, ACPS_STRSY ;  Q5LY70, ACPS_STRT1 ;  Q5M2S6, ACPS_STRT2 ;
DR   Q03IX7, ACPS_STRTD ;  B9DVI4, ACPS_STRU0 ;  C1CFR8, ACPS_STRZJ ;
DR   C1CM35, ACPS_STRZP ;  C1CSW0, ACPS_STRZT ;  Q30SB4, ACPS_SULDN ;
DR   A6Q7U5, ACPS_SULNB ;  Q67K77, ACPS_SYMTH ;  Q2LTJ7, ACPS_SYNAS ;
DR   Q9WZF6, ACPS_THEMA ;  B0KD52, ACPS_THEP3 ;  B0K5Y6, ACPS_THEPX ;
DR   Q72IV9, ACPS_THET2 ;  Q5SII1, ACPS_THET8 ;  Q8R857, ACPS_THETN ;
DR   B5YJG8, ACPS_THEYD ;  Q31HN9, ACPS_THICR ;  Q3SKU1, ACPS_THIDA ;
DR   Q73LF7, ACPS_TREDE ;  O83800, ACPS_TREPA ;  B2S466, ACPS_TREPS ;
DR   B1AJ32, ACPS_UREP2 ;  Q9PQ97, ACPS_UREPA ;  C5CSF9, ACPS_VARPS ;
DR   A1WKY6, ACPS_VEREI ;  A5CWJ8, ACPS_VESOH ;  A5F5H4, ACPS_VIBC3 ;
DR   Q9KPB6, ACPS_VIBCH ;  C3LR00, ACPS_VIBCM ;  Q5E318, ACPS_VIBF1 ;
DR   B5FAG6, ACPS_VIBFM ;  A7MZA4, ACPS_VIBHB ;  Q87LP3, ACPS_VIBPA ;
DR   B7VK75, ACPS_VIBSL ;  Q8DC72, ACPS_VIBVU ;  Q7MHP2, ACPS_VIBVY ;
DR   Q8D303, ACPS_WIGBR ;  Q73GW5, ACPS_WOLPM ;  B3CL63, ACPS_WOLPP ;
DR   Q7M803, ACPS_WOLSU ;  Q5GTK4, ACPS_WOLTR ;  C0R3N6, ACPS_WOLWR ;
DR   A7IM60, ACPS_XANP2 ;  A1JKK7, ACPS_YERE8 ;  A7FFU3, ACPS_YERP3 ;
DR   Q1C5D9, ACPS_YERPA ;  B2KA43, ACPS_YERPB ;  Q8ZCP5, ACPS_YERPE ;
DR   A9R406, ACPS_YERPG ;  Q1CKE0, ACPS_YERPN ;  A4TKX4, ACPS_YERPP ;
DR   Q667V4, ACPS_YERPS ;  B1JRD1, ACPS_YERPY ;  Q5NLS7, ACPS_ZYMMO ;
DR   Q75BZ1, PPT2_ASHGO ;  Q6FJZ5, PPT2_CANGA ;  Q12036, PPT2_YEAST ;
//
ID   2.7.8.8
DE   CDP-diacylglycerol--serine O-phosphatidyltransferase.
AN   CDP-diglycerine-serine O-phosphatidyltransferase.
AN   Phosphatidylserine synthase.
CA   CDP-diacylglycerol + L-serine = CMP + (3-sn-phosphatidyl)-L-serine.
PR   PROSITE; PDOC00321;
DR   P39823, PSS_BACSU  ;  P23830, PSS_ECOLI  ;  Q95ZE2, PSS_ENCCU  ;
DR   P44704, PSS_HAEIN  ;  Q9ZM68, PSS_HELPJ  ;  Q48269, PSS_HELPY  ;
DR   Q58609, PSS_METJA  ;  P59949, PSS_MYCBO  ;  Q9ZBM2, PSS_MYCLE  ;
DR   P96282, PSS_MYCTU  ;  P08456, PSS_YEAST  ;
//
ID   2.7.8.9
DE   Phosphomannan mannosephosphotransferase.
CA   GDP-mannose + (phosphomannan)(n) = GMP + (phosphomannan)(n+1).
//
ID   2.7.8.10
DE   Sphingosine cholinephosphotransferase.
CA   CDP-choline + sphingosine = CMP + sphingosyl-phosphocholine.
//
ID   2.7.8.11
DE   CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
AN   CDP-diacylglycerol--inositol phosphatidyltransferase.
AN   Phosphatidylinositol synthase.
CA   CDP-diacylglycerol + myo-inositol = CMP + phosphatidyl-1D-myo-inositol.
PR   PROSITE; PDOC00321;
DR   O14735, CDIPT_HUMAN;  Q8VDP6, CDIPT_MOUSE;  P70500, CDIPT_RAT  ;
DR   Q8LBA6, PIS1_ARATH ;  Q8GUK6, PIS2_ARATH ;  Q9F7Y9, PISA_MYCSM ;
DR   Q7D6W6, PISA_MYCTU ;  P06197, PIS_YEAST  ;
//
ID   2.7.8.12
DE   CDP-glycerol glycerophosphotransferase.
AN   Teichoic-acid synthase.
CA   CDP-glycerol + (glycerophosphate)(n) = CMP + (glycerophosphate)(n+1).
DR   P13485, TAGF_BACSU ;
//
ID   2.7.8.13
DE   Phospho-N-acetylmuramoyl-pentapeptide-transferase.
AN   MraY transferase.
AN   Phospho-MurNAc-pentapeptide transferase.
AN   Phospho-N-acetylmuramoyl pentapeptide translocase.
AN   Phospho-NAc-muramoyl-pentapeptide translocase (UMP).
AN   Phosphoacetylmuramoylpentapeptide translocase.
AN   Phosphoacetylmuramoylpentapeptidetransferase.
AN   UDP-MurNAc-Ala-gamma-DGlu-Lys-DAla-DAla:undecaprenylphosphate
AN   transferase.
AN   UDP-MurNAc-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala:C(55)-isoprenoid alcohol
AN   transferase.
AN   UDP-MurNAc-pentapeptide phosphotransferase.
CA   UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl
CA   phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-
CA   diphosphoundecaprenol.
CC   -!- In Gram-negative and some Gram-positive organisms the L-lysine is
CC       replaced by meso-2,6-diaminoheptanedioate (meso-2,6-diaminopimelate,
CC       A2pm), which is combined with adjacent residues through its L-center.
CC   -!- The undecaprenol involved is ditrans,octacis-undecaprenol.
PR   PROSITE; PDOC01046;
DR   B0BZI7, MRAY_ACAM1 ;  A1TKC8, MRAY_ACIAC ;  Q6F7D6, MRAY_ACIAD ;
DR   B7IAW6, MRAY_ACIB5 ;  B2I0K2, MRAY_ACIBC ;  Q1IKG7, MRAY_ACIBL ;
DR   B0VPG4, MRAY_ACIBS ;  B0V8P2, MRAY_ACIBY ;  A0LTM0, MRAY_ACIC1 ;
DR   C1F461, MRAY_ACIC5 ;  A5FUK7, MRAY_ACICJ ;  B9MFR5, MRAY_ACIET ;
DR   B7J3V5, MRAY_ACIF2 ;  B5ELC6, MRAY_ACIF5 ;  A1WC09, MRAY_ACISJ ;
DR   A3MY87, MRAY_ACTP2 ;  B3GZK5, MRAY_ACTP7 ;  B0BRH4, MRAY_ACTPJ ;
DR   A6VQN6, MRAY_ACTSZ ;  B9JH54, MRAY_AGRRK ;  Q8UDM5, MRAY_AGRT5 ;
DR   B9JY57, MRAY_AGRVS ;  Q0VS05, MRAY_ALCBS ;  Q0A6J9, MRAY_ALHEH ;
DR   B6ELH8, MRAY_ALISL ;  A6TS64, MRAY_ALKMQ ;  A8MH33, MRAY_ALKOO ;
DR   B4RWY2, MRAY_ALTMD ;  B3ER47, MRAY_AMOA5 ;  B8J8E5, MRAY_ANAD2 ;
DR   Q2IG26, MRAY_ANADE ;  A7HH64, MRAY_ANADF ;  B9KH29, MRAY_ANAMF ;
DR   Q5P9K3, MRAY_ANAMM ;  B4UER8, MRAY_ANASK ;  B9MQ98, MRAY_ANATD ;
DR   Q3MDP5, MRAY_ANAVT ;  B7GGI5, MRAY_ANOFW ;  O66465, MRAY_AQUAE ;
DR   A8EW04, MRAY_ARCB4 ;  Q5P6Z3, MRAY_AROAE ;  A1R5F5, MRAY_ARTAT ;
DR   B8HGW7, MRAY_ARTCA ;  A0JV91, MRAY_ARTS2 ;  A8HZ57, MRAY_AZOC5 ;
DR   B6YS29, MRAY_AZOPC ;  A1K3U3, MRAY_AZOSB ;  C1DQ96, MRAY_AZOVD ;
DR   A7Z4E2, MRAY_BACA2 ;  C3P683, MRAY_BACAA ;  C3L712, MRAY_BACAC ;
DR   A0RHT4, MRAY_BACAH ;  Q81WC8, MRAY_BACAN ;  B7JK01, MRAY_BACC0 ;
DR   Q732F5, MRAY_BACC1 ;  B7IUS3, MRAY_BACC2 ;  C1EPS7, MRAY_BACC3 ;
DR   B7H6P9, MRAY_BACC4 ;  B7HM34, MRAY_BACC7 ;  A7GRN9, MRAY_BACCN ;
DR   B9IVZ0, MRAY_BACCQ ;  Q819Q1, MRAY_BACCR ;  Q636B3, MRAY_BACCZ ;
DR   Q5LIJ4, MRAY_BACFN ;  Q64ZL8, MRAY_BACFR ;  Q9K9S6, MRAY_BACHD ;
DR   Q6HEQ1, MRAY_BACHK ;  Q65JY3, MRAY_BACLD ;  A8FCX8, MRAY_BACP2 ;
DR   Q5WFG7, MRAY_BACSK ;  Q03521, MRAY_BACSU ;  Q8A255, MRAY_BACTN ;
DR   A6L074, MRAY_BACV8 ;  A9VU75, MRAY_BACWK ;  A1UTC8, MRAY_BARBK ;
DR   Q6G2Q2, MRAY_BARHE ;  Q6G121, MRAY_BARQU ;  A9IWA8, MRAY_BART1 ;
DR   Q6MIF7, MRAY_BDEBA ;  B2IGF7, MRAY_BEII9 ;  C5BW62, MRAY_BEUC1 ;
DR   B8DSU2, MRAY_BIFA0 ;  A1A2F2, MRAY_BIFAA ;  B3DQM8, MRAY_BIFLD ;
DR   Q8G4Q7, MRAY_BIFLO ;  Q7VQJ0, MRAY_BLOFL ;  Q493Q4, MRAY_BLOPB ;
DR   Q0SNK7, MRAY_BORAP ;  Q7WFR9, MRAY_BORBR ;  Q44776, MRAY_BORBU ;
DR   B7J1N1, MRAY_BORBZ ;  B5RLC9, MRAY_BORDL ;  Q661W1, MRAY_BORGA ;
DR   B2S014, MRAY_BORHD ;  Q7W4B1, MRAY_BORPA ;  A9I4U2, MRAY_BORPD ;
DR   Q7VUQ0, MRAY_BORPE ;  B5RRC2, MRAY_BORRA ;  A1QZ99, MRAY_BORT9 ;
DR   C0R1X0, MRAY_BRAHW ;  Q89FU4, MRAY_BRAJA ;  A5EPK7, MRAY_BRASB ;
DR   A4YZK6, MRAY_BRASO ;  B2S6Q7, MRAY_BRUA1 ;  Q2YM68, MRAY_BRUA2 ;
DR   Q57C75, MRAY_BRUAB ;  A9M693, MRAY_BRUC2 ;  C0RE73, MRAY_BRUMB ;
DR   P64255, MRAY_BRUME ;  A5VRI0, MRAY_BRUO2 ;  B0CHM3, MRAY_BRUSI ;
DR   P64256, MRAY_BRUSU ;  B8D917, MRAY_BUCA5 ;  P57314, MRAY_BUCAI ;
DR   B8D7C2, MRAY_BUCAT ;  P59436, MRAY_BUCBP ;  B1YSS1, MRAY_BURA4 ;
DR   Q1BZG6, MRAY_BURCA ;  B1JV75, MRAY_BURCC ;  A0K483, MRAY_BURCH ;
DR   B4E6J5, MRAY_BURCJ ;  Q0BIK4, MRAY_BURCM ;  A9AJ19, MRAY_BURM1 ;
DR   A3MR60, MRAY_BURM7 ;  A2S5U8, MRAY_BURM9 ;  Q62GS4, MRAY_BURMA ;
DR   A1V0S1, MRAY_BURMS ;  A3NZL8, MRAY_BURP0 ;  Q3JND5, MRAY_BURP1 ;
DR   A3NDW7, MRAY_BURP6 ;  B2JHG3, MRAY_BURP8 ;  B2SYX9, MRAY_BURPP ;
DR   Q63QJ4, MRAY_BURPS ;  Q39JX3, MRAY_BURS3 ;  Q2SZI6, MRAY_BURTA ;
DR   A4JB91, MRAY_BURVG ;  Q13TY9, MRAY_BURXL ;  A4XI01, MRAY_CALS8 ;
DR   A8Z6N6, MRAY_CAMC1 ;  A7GWQ7, MRAY_CAMC5 ;  A0RQL9, MRAY_CAMFF ;
DR   A7I3M7, MRAY_CAMHC ;  A8FKM0, MRAY_CAMJ8 ;  Q9PI72, MRAY_CAMJE ;
DR   A1VYF0, MRAY_CAMJJ ;  Q5HW33, MRAY_CAMJR ;  B9KEZ5, MRAY_CAMLR ;
DR   Q3AAE3, MRAY_CARHZ ;  B8H097, MRAY_CAUCN ;  B0T834, MRAY_CAUSK ;
DR   B3PCM3, MRAY_CELJU ;  A9WG76, MRAY_CHLAA ;  Q5L520, MRAY_CHLAB ;
DR   B8G5X7, MRAY_CHLAD ;  Q3ANV6, MRAY_CHLCH ;  Q821S0, MRAY_CHLCV ;
DR   Q255W8, MRAY_CHLFF ;  B3EIL1, MRAY_CHLL2 ;  Q9PLG6, MRAY_CHLMU ;
DR   B3QLW7, MRAY_CHLP8 ;  B3EQC1, MRAY_CHLPB ;  A1BJY1, MRAY_CHLPD ;
DR   Q9Z706, MRAY_CHLPN ;  B9LKJ6, MRAY_CHLSY ;  B0B8Y3, MRAY_CHLT2 ;
DR   B3QWT4, MRAY_CHLT3 ;  Q3KKT5, MRAY_CHLTA ;  B0BAL2, MRAY_CHLTB ;
DR   Q8KGD1, MRAY_CHLTE ;  O84762, MRAY_CHLTR ;  Q1QVG4, MRAY_CHRSD ;
DR   Q7NPZ6, MRAY_CHRVO ;  A8ALK9, MRAY_CITK8 ;  A5CS54, MRAY_CLAM3 ;
DR   B0RIJ0, MRAY_CLAMS ;  Q97H86, MRAY_CLOAB ;  A6LTS6, MRAY_CLOB8 ;
DR   B2V4V5, MRAY_CLOBA ;  B2TS25, MRAY_CLOBB ;  Q182Y8, MRAY_CLOD6 ;
DR   B9E0W0, MRAY_CLOK1 ;  A5N7E7, MRAY_CLOK5 ;  A0Q060, MRAY_CLONN ;
DR   Q0TP97, MRAY_CLOP1 ;  Q8XJA1, MRAY_CLOPE ;  Q0SRW4, MRAY_CLOPS ;
DR   Q894B9, MRAY_CLOTE ;  A3DE29, MRAY_CLOTH ;  Q47VQ6, MRAY_COLP3 ;
DR   C3PHF9, MRAY_CORA7 ;  Q6NGC5, MRAY_CORDI ;  Q8FNT7, MRAY_COREF ;
DR   A4QFM6, MRAY_CORGB ;  Q8NNN2, MRAY_CORGL ;  Q4JW98, MRAY_CORJK ;
DR   C4LI47, MRAY_CORK4 ;  B1VHC7, MRAY_CORU7 ;  B6J5K9, MRAY_COXB1 ;
DR   B6J2Q9, MRAY_COXB2 ;  A9KES2, MRAY_COXBN ;  A9NA35, MRAY_COXBR ;
DR   Q83F26, MRAY_COXBU ;  Q0K6M1, MRAY_CUPNH ;  Q46WZ1, MRAY_CUPPJ ;
DR   B3R6W2, MRAY_CUPTR ;  B7KDB2, MRAY_CYAP7 ;  B7JVF4, MRAY_CYAP8 ;
DR   Q11RH2, MRAY_CYTH3 ;  Q47AA1, MRAY_DECAR ;  C1CW54, MRAY_DEIDV ;
DR   Q9RTD0, MRAY_DEIRA ;  A9BUK3, MRAY_DELAS ;  B8FBS1, MRAY_DESAA ;
DR   C6BYG9, MRAY_DESAD ;  C0Q8P0, MRAY_DESAH ;  B1I4C7, MRAY_DESAP ;
DR   B8IZT8, MRAY_DESDA ;  Q313Q6, MRAY_DESDG ;  B8FT59, MRAY_DESHD ;
DR   Q24TE3, MRAY_DESHY ;  C4XK72, MRAY_DESMR ;  A8ZXW6, MRAY_DESOH ;
DR   Q6AJ51, MRAY_DESPS ;  A4J2A8, MRAY_DESRM ;  Q728U5, MRAY_DESVH ;
DR   A1VBE5, MRAY_DESVV ;  A5EY06, MRAY_DICNV ;  B5YEL6, MRAY_DICT6 ;
DR   B8E328, MRAY_DICTD ;  A8LSB0, MRAY_DINSH ;  A7ZHH8, MRAY_ECO24 ;
DR   B7UID7, MRAY_ECO27 ;  B7MAL0, MRAY_ECO45 ;  B7LFV7, MRAY_ECO55 ;
DR   P64258, MRAY_ECO57 ;  B5YZC3, MRAY_ECO5E ;  B7NHJ3, MRAY_ECO7I ;
DR   B7MNU6, MRAY_ECO81 ;  B7M130, MRAY_ECO8A ;  C4ZRI2, MRAY_ECOBW ;
DR   B1XC64, MRAY_ECODH ;  A7ZW39, MRAY_ECOHS ;  A1A7D2, MRAY_ECOK1 ;
DR   Q0TLQ2, MRAY_ECOL5 ;  P64257, MRAY_ECOL6 ;  B1IR91, MRAY_ECOLC ;
DR   P0A6W3, MRAY_ECOLI ;  B7N7W0, MRAY_ECOLU ;  B6HZ64, MRAY_ECOSE ;
DR   B1LG24, MRAY_ECOSM ;  Q1RGA8, MRAY_ECOUT ;  C5B9F3, MRAY_EDWI9 ;
DR   A4W6J0, MRAY_ENT38 ;  O07107, MRAY_ENTFA ;  O07668, MRAY_ENTHR ;
DR   A7MIF2, MRAY_ENTS8 ;  Q6D0I0, MRAY_ERWCT ;  B2VD87, MRAY_ERWT9 ;
DR   Q2NCZ3, MRAY_ERYLH ;  B7LWF0, MRAY_ESCF3 ;  A7HK75, MRAY_FERNB ;
DR   A5FIY0, MRAY_FLAJ1 ;  A6H198, MRAY_FLAPJ ;  Q0RNP4, MRAY_FRAAA ;
DR   B0TZ73, MRAY_FRAP2 ;  Q2JD53, MRAY_FRASC ;  Q14J06, MRAY_FRAT1 ;
DR   A7NDX5, MRAY_FRATF ;  Q2A1Z8, MRAY_FRATH ;  B2SDR9, MRAY_FRATM ;
DR   A0Q5C1, MRAY_FRATN ;  Q0BKM7, MRAY_FRATO ;  Q5NHK4, MRAY_FRATT ;
DR   A4IZH0, MRAY_FRATW ;  Q8RDQ0, MRAY_FUSNN ;  C1A8A7, MRAY_GEMAT ;
DR   B5EBP8, MRAY_GEOBB ;  Q5L0X8, MRAY_GEOKA ;  B3E3Y5, MRAY_GEOLS ;
DR   Q39YM2, MRAY_GEOMG ;  Q748D3, MRAY_GEOSL ;  C6DZK3, MRAY_GEOSM ;
DR   C5D8M1, MRAY_GEOSW ;  A4IM06, MRAY_GEOTN ;  Q7NEY9, MRAY_GLOVI ;
DR   A9H0I1, MRAY_GLUDA ;  Q5FUJ8, MRAY_GLUOX ;  Q0BV22, MRAY_GRABC ;
DR   A0M530, MRAY_GRAFK ;  Q7VP57, MRAY_HAEDU ;  Q4QLG1, MRAY_HAEI8 ;
DR   A5UCX1, MRAY_HAEIE ;  A5UIQ9, MRAY_HAEIG ;  P45062, MRAY_HAEIN ;
DR   B8F3B3, MRAY_HAEPS ;  Q0I1D6, MRAY_HAES1 ;  B0US64, MRAY_HAES2 ;
DR   Q2S9Y9, MRAY_HAHCH ;  A1WYU6, MRAY_HALHL ;  Q17XN0, MRAY_HELAH ;
DR   Q7VGZ9, MRAY_HELHP ;  B0TGB7, MRAY_HELMI ;  B6JL77, MRAY_HELP2 ;
DR   Q1CU36, MRAY_HELPH ;  Q9ZLY1, MRAY_HELPJ ;  B2UTZ3, MRAY_HELPS ;
DR   O25235, MRAY_HELPY ;  A4G8U1, MRAY_HERAR ;  B4U9Q9, MRAY_HYDS0 ;
DR   Q0BXT9, MRAY_HYPNA ;  Q5R0M4, MRAY_IDILO ;  A6T2G1, MRAY_JANMA ;
DR   Q28NN1, MRAY_JANSC ;  A6WCX7, MRAY_KINRD ;  B5Y1V0, MRAY_KLEP3 ;
DR   A6T4N0, MRAY_KLEP7 ;  B2GJQ1, MRAY_KOCRD ;  C5CDR2, MRAY_KOSOT ;
DR   Q5FKV4, MRAY_LACAC ;  Q03QH3, MRAY_LACBA ;  Q039R9, MRAY_LACC3 ;
DR   Q1GAT7, MRAY_LACDA ;  Q04B74, MRAY_LACDB ;  B2GB76, MRAY_LACF3 ;
DR   Q042P7, MRAY_LACGA ;  A8YUN7, MRAY_LACH4 ;  Q74JY6, MRAY_LACJO ;
DR   Q9CH70, MRAY_LACLA ;  A2RLT1, MRAY_LACLM ;  Q02ZY6, MRAY_LACLS ;
DR   Q88V79, MRAY_LACPL ;  A5VJ31, MRAY_LACRD ;  B2G6K3, MRAY_LACRJ ;
DR   Q1WT98, MRAY_LACS1 ;  Q38XN0, MRAY_LACSS ;  C1D5M0, MRAY_LARHH ;
DR   Q1MPC2, MRAY_LAWIP ;  Q5X1S3, MRAY_LEGPA ;  A5IAV9, MRAY_LEGPC ;
DR   Q5ZSA2, MRAY_LEGPH ;  Q5WTI4, MRAY_LEGPL ;  Q6AE61, MRAY_LEIXX ;
DR   B0S986, MRAY_LEPBA ;  Q04V92, MRAY_LEPBJ ;  Q04Y84, MRAY_LEPBL ;
DR   B0SRS0, MRAY_LEPBP ;  B1XYR0, MRAY_LEPCP ;  Q72R82, MRAY_LEPIC ;
DR   Q8F4J3, MRAY_LEPIN ;  B1MXV8, MRAY_LEUCK ;  Q03W33, MRAY_LEUMM ;
DR   Q929Y0, MRAY_LISIN ;  C1KWZ0, MRAY_LISMC ;  Q71XX6, MRAY_LISMF ;
DR   Q8Y5M0, MRAY_LISMO ;  A0AKD7, MRAY_LISW6 ;  Q2W0H6, MRAY_MAGSA ;
DR   A0L5N4, MRAY_MAGSM ;  Q65RY3, MRAY_MANSM ;  A1U3G1, MRAY_MARAV ;
DR   Q0AMW4, MRAY_MARMM ;  A6VYK1, MRAY_MARMS ;  Q11GS2, MRAY_MESSB ;
DR   B7KU72, MRAY_METC4 ;  Q604V4, MRAY_METCA ;  Q1GYZ8, MRAY_METFK ;
DR   B3DVW4, MRAY_METI4 ;  B8IMW7, MRAY_METNO ;  B1Z8W9, MRAY_METPB ;
DR   A2SCY2, MRAY_METPP ;  B1LXZ8, MRAY_METRJ ;  B0UFH5, MRAY_METS4 ;
DR   B8ETL9, MRAY_METSB ;  O26830, MRAY_METTH ;  B0JFF7, MRAY_MICAN ;
DR   C5CA33, MRAY_MICLC ;  Q2RK82, MRAY_MOOTA ;  A0QF49, MRAY_MYCA1 ;
DR   B1MP34, MRAY_MYCA9 ;  P64260, MRAY_MYCBO ;  A1KKJ9, MRAY_MYCBP ;
DR   C1AQ72, MRAY_MYCBT ;  A4TBF2, MRAY_MYCGI ;  B8ZQP7, MRAY_MYCLB ;
DR   O69555, MRAY_MYCLE ;  B2HGR9, MRAY_MYCMM ;  Q73YQ5, MRAY_MYCPA ;
DR   A0R019, MRAY_MYCS2 ;  A3Q1M1, MRAY_MYCSJ ;  A1UI57, MRAY_MYCSK ;
DR   Q1B6W8, MRAY_MYCSS ;  A5U4I3, MRAY_MYCTA ;  P64259, MRAY_MYCTU ;
DR   A0PTJ0, MRAY_MYCUA ;  A1TAX1, MRAY_MYCVP ;  Q1D0S7, MRAY_MYXXD ;
DR   B9L7V6, MRAY_NAUPA ;  Q5F6L4, MRAY_NEIG1 ;  B4RQC9, MRAY_NEIG2 ;
DR   A9M2H7, MRAY_NEIM0 ;  Q9JSZ3, MRAY_NEIMA ;  Q9K0Y6, MRAY_NEIMB ;
DR   A1KVL7, MRAY_NEIMF ;  Q0AJD8, MRAY_NITEC ;  Q82VS6, MRAY_NITEU ;
DR   Q1QNU6, MRAY_NITHX ;  Q2Y635, MRAY_NITMU ;  Q3J786, MRAY_NITOC ;
DR   A6Q1R7, MRAY_NITSB ;  Q3STT1, MRAY_NITWN ;  Q5YYY2, MRAY_NOCFA ;
DR   A1SL83, MRAY_NOCSJ ;  B2J5G4, MRAY_NOSP7 ;  Q8YP83, MRAY_NOSS1 ;
DR   Q2G998, MRAY_NOVAD ;  Q8ER51, MRAY_OCEIH ;  A6WZQ3, MRAY_OCHA4 ;
DR   Q04ES8, MRAY_OENOB ;  B6JCF5, MRAY_OLICO ;  B1ZU32, MRAY_OPITP ;
DR   B3CVD3, MRAY_ORITI ;  A6LEU6, MRAY_PARD8 ;  A1AZK6, MRAY_PARDP ;
DR   A7HVU4, MRAY_PARL1 ;  Q6MBS3, MRAY_PARUW ;  P57816, MRAY_PASMU ;
DR   C6DEU6, MRAY_PECCP ;  Q03EY0, MRAY_PEDPA ;  Q3A2G3, MRAY_PELCD ;
DR   Q3B126, MRAY_PELLD ;  B4SHE7, MRAY_PELPB ;  A1AU64, MRAY_PELPD ;
DR   A5D148, MRAY_PELTS ;  Q4FPK2, MRAY_PELUB ;  A9BGS8, MRAY_PETMO ;
DR   B4RFS3, MRAY_PHEZH ;  Q7N144, MRAY_PHOLL ;  Q6LMF3, MRAY_PHOPR ;
DR   A1VST9, MRAY_POLNA ;  B1XT06, MRAY_POLNS ;  Q12EL8, MRAY_POLSJ ;
DR   A4SV71, MRAY_POLSQ ;  B2RIE8, MRAY_PORG3 ;  Q7MWM6, MRAY_PORGI ;
DR   B4S6R2, MRAY_PROA2 ;  Q6A9Q5, MRAY_PROAC ;  A3PFJ8, MRAY_PROM0 ;
DR   A8G7L4, MRAY_PROM2 ;  A2BZ97, MRAY_PROM5 ;  Q317T2, MRAY_PROM9 ;
DR   Q7V9F5, MRAY_PROMA ;  B4F114, MRAY_PROMH ;  Q7V3S7, MRAY_PROMM ;
DR   Q7UZF8, MRAY_PROMP ;  Q46I69, MRAY_PROMT ;  A4SH05, MRAY_PROVI ;
DR   Q48EF5, MRAY_PSE14 ;  Q15Q14, MRAY_PSEA6 ;  A6VB88, MRAY_PSEA7 ;
DR   B7UZJ3, MRAY_PSEA8 ;  Q02H25, MRAY_PSEAB ;  Q9HVZ8, MRAY_PSEAE ;
DR   Q1I5B5, MRAY_PSEE4 ;  Q4K6J0, MRAY_PSEF5 ;  C3KCS7, MRAY_PSEFS ;
DR   Q3IG01, MRAY_PSEHT ;  A4XQS1, MRAY_PSEMY ;  A5W8Q3, MRAY_PSEP1 ;
DR   Q3K741, MRAY_PSEPF ;  B0KFS9, MRAY_PSEPG ;  Q88N79, MRAY_PSEPK ;
DR   B1J3K9, MRAY_PSEPW ;  Q87WY2, MRAY_PSESM ;  Q4ZNY7, MRAY_PSEU2 ;
DR   A4VIH5, MRAY_PSEU5 ;  Q4FQ10, MRAY_PSYA2 ;  Q1Q851, MRAY_PSYCK ;
DR   A1SU16, MRAY_PSYIN ;  A5WBQ6, MRAY_PSYWF ;  Q1LIM3, MRAY_RALME ;
DR   B2UCY0, MRAY_RALPJ ;  Q8XVI4, MRAY_RALSO ;  A9WRE1, MRAY_RENSM ;
DR   B3PTW3, MRAY_RHIE6 ;  Q2K6B8, MRAY_RHIEC ;  Q1ME30, MRAY_RHIL3 ;
DR   Q98KB0, MRAY_RHILO ;  B5ZWJ7, MRAY_RHILW ;  Q52952, MRAY_RHIME ;
DR   C3MEN2, MRAY_RHISN ;  B6IRG5, MRAY_RHOCS ;  Q21SW6, MRAY_RHOFD ;
DR   C1AU58, MRAY_RHOOB ;  Q2IYL1, MRAY_RHOP2 ;  Q07PT6, MRAY_RHOP5 ;
DR   Q6N408, MRAY_RHOPA ;  Q216E1, MRAY_RHOPB ;  Q133W8, MRAY_RHOPS ;
DR   B3QFN4, MRAY_RHOPT ;  Q2RVU1, MRAY_RHORT ;  A3PHS2, MRAY_RHOS1 ;
DR   Q3J4M8, MRAY_RHOS4 ;  A4WQD0, MRAY_RHOS5 ;  B9KNJ3, MRAY_RHOSK ;
DR   Q0SHR8, MRAY_RHOSR ;  C3PP35, MRAY_RICAE ;  A8GP69, MRAY_RICAH ;
DR   A8GVM4, MRAY_RICB8 ;  Q1RI79, MRAY_RICBR ;  A8EY83, MRAY_RICCK ;
DR   Q92H61, MRAY_RICCN ;  Q4UMI7, MRAY_RICFE ;  A8F278, MRAY_RICM5 ;
DR   Q9AKP2, MRAY_RICMO ;  Q9ZCW0, MRAY_RICPR ;  C4K1S5, MRAY_RICPU ;
DR   Q9AKI9, MRAY_RICRI ;  B0BYF0, MRAY_RICRO ;  A8GSX5, MRAY_RICRS ;
DR   Q9AKD8, MRAY_RICTY ;  Q1AVX0, MRAY_RUBXD ;  A1AVY0, MRAY_RUTMC ;
DR   Q21MH2, MRAY_SACD2 ;  A4FLW3, MRAY_SACEN ;  B5F7W1, MRAY_SALA4 ;
DR   A8LX83, MRAY_SALAI ;  A9MQC5, MRAY_SALAR ;  Q57TD3, MRAY_SALCH ;
DR   B5FI69, MRAY_SALDC ;  B5R2M1, MRAY_SALEP ;  B5RH61, MRAY_SALG2 ;
DR   B4TJ84, MRAY_SALHS ;  B4SU47, MRAY_SALNS ;  Q5PDC3, MRAY_SALPA ;
DR   A9MZL6, MRAY_SALPB ;  C0Q5I3, MRAY_SALPC ;  B5BLB9, MRAY_SALPK ;
DR   Q2S531, MRAY_SALRD ;  B4TXH5, MRAY_SALSV ;  Q8Z9H1, MRAY_SALTI ;
DR   A4X9R8, MRAY_SALTO ;  Q8ZRU5, MRAY_SALTY ;  A8G9S4, MRAY_SERP5 ;
DR   A1S2F6, MRAY_SHEAM ;  B8E695, MRAY_SHEB2 ;  A3CZL8, MRAY_SHEB5 ;
DR   A6WIC8, MRAY_SHEB8 ;  A9KY26, MRAY_SHEB9 ;  Q12SC9, MRAY_SHEDO ;
DR   Q07WI2, MRAY_SHEFN ;  B0TQN4, MRAY_SHEHH ;  A3QIM4, MRAY_SHELP ;
DR   Q8E9P5, MRAY_SHEON ;  A8H987, MRAY_SHEPA ;  A4Y2N3, MRAY_SHEPC ;
DR   B8CNK8, MRAY_SHEPW ;  A0L1P5, MRAY_SHESA ;  A8FQ97, MRAY_SHESH ;
DR   Q0HE80, MRAY_SHESM ;  Q0HZR9, MRAY_SHESR ;  A1REZ3, MRAY_SHESW ;
DR   Q9F1N3, MRAY_SHEVD ;  B1KKY0, MRAY_SHEWM ;  B2U292, MRAY_SHIB3 ;
DR   Q326E8, MRAY_SHIBS ;  Q32K05, MRAY_SHIDS ;  Q0T8B0, MRAY_SHIF8 ;
DR   P0A6W4, MRAY_SHIFL ;  Q3Z5S2, MRAY_SHISS ;  Q5LU74, MRAY_SILPO ;
DR   Q1GF14, MRAY_SILST ;  A6UB88, MRAY_SINMW ;  Q2NVV4, MRAY_SODGM ;
DR   Q01Q45, MRAY_SOLUE ;  A9FI43, MRAY_SORC5 ;  Q1GRX6, MRAY_SPHAL ;
DR   A5VDC9, MRAY_SPHWW ;  A7X1C2, MRAY_STAA1 ;  A6U102, MRAY_STAA2 ;
DR   Q2FHQ5, MRAY_STAA3 ;  Q2FZ93, MRAY_STAA8 ;  A5IS68, MRAY_STAA9 ;
DR   Q2YXE0, MRAY_STAAB ;  Q5HGP9, MRAY_STAAC ;  A6QG82, MRAY_STAAE ;
DR   P68782, MRAY_STAAM ;  P68783, MRAY_STAAN ;  Q6GHQ3, MRAY_STAAR ;
DR   Q6GA30, MRAY_STAAS ;  A8Z3M3, MRAY_STAAT ;  P0C1R8, MRAY_STAAU ;
DR   Q8NX36, MRAY_STAAW ;  B9DPR2, MRAY_STACT ;  Q5HQ10, MRAY_STAEQ ;
DR   Q8CPK7, MRAY_STAES ;  Q4L5N3, MRAY_STAHJ ;  Q49WW4, MRAY_STAS1 ;
DR   Q3K391, MRAY_STRA1 ;  Q8E779, MRAY_STRA3 ;  Q8E1R5, MRAY_STRA5 ;
DR   Q82AD9, MRAY_STRAW ;  P56833, MRAY_STRCO ;  C0M7A5, MRAY_STRE4 ;
DR   B4U4K1, MRAY_STREM ;  A8AVT2, MRAY_STRGC ;  B1W0I7, MRAY_STRGG ;
DR   Q8DVM4, MRAY_STRMU ;  Q99YK2, MRAY_STRP1 ;  Q04MC4, MRAY_STRP2 ;
DR   P0DB42, MRAY_STRP3 ;  B5E6Z5, MRAY_STRP4 ;  Q5XAL6, MRAY_STRP6 ;
DR   C1CBB5, MRAY_STRP7 ;  Q8NZY2, MRAY_STRP8 ;  Q1JAG8, MRAY_STRPB ;
DR   Q1JKM0, MRAY_STRPC ;  Q1JFL1, MRAY_STRPD ;  Q1J5G1, MRAY_STRPF ;
DR   A2RD43, MRAY_STRPG ;  B1I956, MRAY_STRPI ;  B8ZL54, MRAY_STRPJ ;
DR   Q48RZ3, MRAY_STRPM ;  P0CB59, MRAY_STRPN ;  P0DB43, MRAY_STRPQ ;
DR   B2ISQ5, MRAY_STRPS ;  B5XML0, MRAY_STRPZ ;  Q8DR69, MRAY_STRR6 ;
DR   A4W3H1, MRAY_STRS2 ;  C0MGW1, MRAY_STRS7 ;  A3CPZ6, MRAY_STRSV ;
DR   A4VX68, MRAY_STRSY ;  Q5LY94, MRAY_STRT1 ;  Q5M2U9, MRAY_STRT2 ;
DR   Q03J12, MRAY_STRTD ;  B9DV75, MRAY_STRU0 ;  C1CIK1, MRAY_STRZP ;
DR   C1CPL3, MRAY_STRZT ;  Q30Q39, MRAY_SULDN ;  A6QCC3, MRAY_SULNB ;
DR   Q67Q50, MRAY_SYMTH ;  Q2LR51, MRAY_SYNAS ;  Q31RY5, MRAY_SYNE7 ;
DR   Q2JT76, MRAY_SYNJA ;  Q2JMC1, MRAY_SYNJB ;  B1XNS2, MRAY_SYNP2 ;
DR   Q5N2C7, MRAY_SYNP6 ;  A5GPT3, MRAY_SYNPW ;  Q7U3B6, MRAY_SYNPX ;
DR   A5GX19, MRAY_SYNR3 ;  Q0I604, MRAY_SYNS3 ;  Q3AVL6, MRAY_SYNS9 ;
DR   Q3AG75, MRAY_SYNSC ;  Q55986, MRAY_SYNY3 ;  C5BP37, MRAY_TERTT ;
DR   Q8DK95, MRAY_THEEB ;  Q47QX2, MRAY_THEFY ;  Q9WY77, MRAY_THEMA ;
DR   B9K6P4, MRAY_THENN ;  A5IKI6, MRAY_THEP1 ;  B0K8K4, MRAY_THEP3 ;
DR   B0K3H3, MRAY_THEPX ;  B1L9R8, MRAY_THESQ ;  Q8R9G3, MRAY_THETN ;
DR   B5YFT8, MRAY_THEYD ;  Q31I62, MRAY_THICR ;  Q3SMH6, MRAY_THIDA ;
DR   B8GMM6, MRAY_THISH ;  C4LA22, MRAY_TOLAT ;  O83365, MRAY_TREPA ;
DR   B2S2U2, MRAY_TREPS ;  Q83HJ8, MRAY_TROW8 ;  Q83GN4, MRAY_TROWT ;
DR   B1GZI2, MRAY_UNCTG ;  C5CNF1, MRAY_VARPS ;  A1WRK8, MRAY_VEREI ;
DR   A5CXA6, MRAY_VESOH ;  A5F5N2, MRAY_VIBC3 ;  Q9KPG4, MRAY_VIBCH ;
DR   C3LQU9, MRAY_VIBCM ;  Q5E2P7, MRAY_VIBF1 ;  B5FB38, MRAY_VIBFM ;
DR   A7MWL2, MRAY_VIBHB ;  Q87SG7, MRAY_VIBPA ;  B7VJ00, MRAY_VIBSL ;
DR   Q8DEK7, MRAY_VIBVU ;  Q7MNV4, MRAY_VIBVY ;  Q8D2Z3, MRAY_WIGBR ;
DR   Q73G61, MRAY_WOLPM ;  Q7M7X0, MRAY_WOLSU ;  Q5GRZ3, MRAY_WOLTR ;
DR   C0R4W3, MRAY_WOLWR ;  Q8PPB0, MRAY_XANAC ;  Q3BXF4, MRAY_XANC5 ;
DR   Q4UQW8, MRAY_XANC8 ;  B0RVA7, MRAY_XANCB ;  Q8PCK2, MRAY_XANCP ;
DR   Q2NZB6, MRAY_XANOM ;  B2SNZ1, MRAY_XANOP ;  Q5GW39, MRAY_XANOR ;
DR   A7IGE9, MRAY_XANP2 ;  B2I9B5, MRAY_XYLF2 ;  Q9PF83, MRAY_XYLFA ;
DR   B0U4Z9, MRAY_XYLFM ;  Q87AF7, MRAY_XYLFT ;  A1JJJ0, MRAY_YERE8 ;
DR   A7FM69, MRAY_YERP3 ;  Q1C211, MRAY_YERPA ;  B2K4E3, MRAY_YERPB ;
DR   Q8ZIF2, MRAY_YERPE ;  A9R127, MRAY_YERPG ;  Q1CMN0, MRAY_YERPN ;
DR   A4TQ86, MRAY_YERPP ;  Q66EK8, MRAY_YERPS ;  B1JK84, MRAY_YERPY ;
DR   P56834, MRAY_ZYMMO ;
//
ID   2.7.8.14
DE   CDP-ribitol ribitolphosphotransferase.
AN   Teichoic-acid synthase.
CA   CDP-ribitol + (ribitol phosphate)(n) = CMP + (ribitol phosphate)(n+1).
CC   -!- Formerly EC 2.4.1.55.
DR   Q8RKJ2, TARL_BACPZ ;
//
ID   2.7.8.15
DE   UDP-N-acetylglucosamine--dolichyl-phosphate
DE   N-acetylglucosaminephosphotransferase.
AN   GlcNAc-1-P transferase.
AN   N-acetylglucosamine-1-phosphate transferase.
CA   UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-
CA   glucosaminyl-diphosphodolichol.
DR   Q5EA65, GPT_BOVIN  ;  P24140, GPT_CRIGR  ;  P23338, GPT_CRILO  ;
DR   P0CD61, GPT_DICDI  ;  Q9H3H5, GPT_HUMAN  ;  P42864, GPT_LEIAM  ;
DR   P42867, GPT_MOUSE  ;  P42881, GPT_SCHPO  ;  P39465, GPT_SULAC  ;
DR   P96000, GPT_SULSO  ;  P07286, GPT_YEAST  ;
//
ID   2.7.8.16
DE   Transferred entry: 2.7.8.2.
//
ID   2.7.8.17
DE   UDP-N-acetylglucosamine--lysosomal-enzyme
DE   N-acetylglucosaminephosphotransferase.
AN   N-acetylglucosaminylphosphotransferase.
CA   UDP-N-acetyl-D-glucosamine + lysosomal-enzyme D-mannose = UMP +
CA   lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose.
CC   -!- Some other glycoproteins with high-mannose can act as acceptors,
CC       but much more slowly than lysosomal enzymes.
DR   Q5RGJ8, GNPTA_DANRE;  Q3T906, GNPTA_HUMAN;  Q69ZN6, GNPTA_MOUSE;
//
ID   2.7.8.18
DE   UDP-galactose--UDP-N-acetylglucosamine galactose phosphotransferase.
CA   UDP-galactose + UDP-N-acetyl-D-glucosamine = UMP + UDP-N-acetyl-6-
CA   (D-galactose-1-phospho)-D-glucosamine.
CC   -!- N-acetylglucosamine end-groups in glycoproteins can also act as
CC       acceptors.
//
ID   2.7.8.19
DE   UDP-glucose--glycoprotein glucose phosphotransferase.
AN   GlcPTase.
CA   UDP-glucose + glycoprotein D-mannose = UMP + glycoprotein 6-(D-glucose-1-
CA   phospho)-D-mannose.
CC   -!- Penultimate mannose residues on oligomannose type glycoproteins can
CC       act as acceptors.
//
ID   2.7.8.20
DE   Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase.
AN   Phosphoglycerol transferase.
CA   Phosphatidylglycerol + membrane-derived-oligosaccharide D-glucose = 1,2-
CA   diacyl-sn-glycerol + membrane-derived-oligosaccharide 6-(glycerophospho)-
CA   D-glucose.
CC   -!- 1,2-beta- and 1,6-beta-linked glucose residues in membrane
CC       polysaccharides and in synthetic glucosides can act as acceptors.
DR   A8AM07, OPGB_CITK8 ;  A7ZVP9, OPGB_ECO24 ;  B7UQY8, OPGB_ECO27 ;
DR   B7MNB1, OPGB_ECO45 ;  B7LE10, OPGB_ECO55 ;  Q8XB59, OPGB_ECO57 ;
DR   B5Z4P2, OPGB_ECO5E ;  B7NVC9, OPGB_ECO7I ;  B7N380, OPGB_ECO81 ;
DR   B7LXS2, OPGB_ECO8A ;  C4ZT42, OPGB_ECOBW ;  A8A888, OPGB_ECOHS ;
DR   Q0T8V3, OPGB_ECOL5 ;  Q8FA73, OPGB_ECOL6 ;  B1IS59, OPGB_ECOLC ;
DR   P39401, OPGB_ECOLI ;  B7NH28, OPGB_ECOLU ;  B6I2P2, OPGB_ECOSE ;
DR   B1LEG3, OPGB_ECOSM ;  Q1R2E6, OPGB_ECOUT ;  B7LMY4, OPGB_ESCF3 ;
DR   B5F500, OPGB_SALA4 ;  A9MRX7, OPGB_SALAR ;  Q57G63, OPGB_SALCH ;
DR   B5FTA1, OPGB_SALDC ;  B4TGX6, OPGB_SALHS ;  B4T4E6, OPGB_SALNS ;
DR   A9N7A9, OPGB_SALPB ;  B4TU18, OPGB_SALSV ;  Q8Z0W2, OPGB_SALTI ;
DR   Q8ZJX6, OPGB_SALTY ;  B2TZP2, OPGB_SHIB3 ;  Q83IH7, OPGB_SHIFL ;
DR   Q8PQA7, OPGB_XANAC ;  Q3BYI6, OPGB_XANC5 ;  B0RMT0, OPGB_XANCB ;
DR   Q8PDD7, OPGB_XANCP ;
//
ID   2.7.8.21
DE   Membrane-oligosaccharide glycerophosphotransferase.
AN   Periplasmic phosphoglycerotransferase.
AN   Phosphoglycerol cyclase.
CA   Transfer of a glycerophospho group from one membrane-derived
CA   oligosaccharide to another.
CC   -!- Beta-linked glucose residues in simple glucosides, such as
CC       gentiobiose, can act as acceptors.
CC   -!- In the presence of low concentrations of acceptor, free cyclic 1,2-
CC       phosphoglycerol is formed.
//
ID   2.7.8.22
DE   1-alkenyl-2-acylglycerol choline phosphotransferase.
CA   CDP-choline + 1-alkenyl-2-acylglycerol = CMP + plasmenylcholine.
//
ID   2.7.8.23
DE   Carboxyvinyl-carboxyphosphonate phosphorylmutase.
AN   Carboxyphosphonoenolpyruvate phosphonomutase.
AN   CPEP phosphonomutase.
CA   1-carboxyvinyl carboxyphosphonate = 3-(hydrohydroxyphosphoryl)pyruvate +
CA   CO(2).
CC   -!- Catalyzes the transfer and decarboxylation of the
CC       carboxy(hydroxy)phosphoryl group, HOOC-P(O)(OH)- (phosphoryl being a
CC       3-valent group), in the formation of an unusual C-P bond that is
CC       involved in the biosynthesis of the antibiotic bialaphos.
DR   O49290, CPPM_ARATH ;  P11435, CPPM_STRHY ;
//
ID   2.7.8.24
DE   Phosphatidylcholine synthase.
AN   CDP-diglyceride-choline O-phosphatidyltransferase.
AN   PC synthase.
CA   CDP-diacylglycerol + choline = CMP + phosphatidylcholine.
CF   Manganese or magnesium.
DR   Q98MN3, PCS_RHILO  ;  Q9KJY8, PCS_RHIME  ;
//
ID   2.7.8.25
DE   Triphosphoribosyl-dephospho-CoA synthase.
AN   2'-(5''-triphosphoribosyl)-3-dephospho-CoA synthase.
CA   ATP + 3-dephospho-CoA = 2'-(5-triphosphoribosyl)-3'-dephospho-CoA +
CA   adenine.
CC   -!- ATP cannot be replaced by GTP, CTP, UTP, ADP or AMP.
CC   -!- The reaction involves the formation of a new alpha (1''->2')
CC       glycosidic bond between the two ribosyl moieties, with concomitant
CC       displacement of the adenine moiety of ATP.
CC   -!- The 2'-(5-triphosphoribosyl)-3'-dephospho-CoA produced can be
CC       transferred by EC 2.7.7.61 to the apo-[acyl-carrier-protein] subunit
CC       (gamma-subunit) of EC 4.1.3.6 thus converting it from an apo-enzyme
CC       into a holo-enzyme.
CC   -!- Alternatively, it can be transferred to the apo-ACP subunit of
CC       malonate decarboxylase by the action of EC 2.7.7.66.
DR   Q57TJ8, CITG1_SALCH;  Q5PKJ2, CITG1_SALPA;  Q8Z9M0, CITG1_SALTI;
DR   Q8ZRX9, CITG1_SALTY;  Q57RV7, CITG2_SALCH;  Q5PMA7, CITG2_SALPA;
DR   Q8Z8J2, CITG2_SALTI;  Q8ZR14, CITG2_SALTY;  A8AJJ2, CITG_CITK8 ;
DR   A7ZIZ9, CITG_ECO24 ;  B7UKQ5, CITG_ECO27 ;  B7MF26, CITG_ECO45 ;
DR   B7L8J6, CITG_ECO55 ;  P58161, CITG_ECO57 ;  B7NLX3, CITG_ECO7I ;
DR   B7MRQ1, CITG_ECO81 ;  B7M4U5, CITG_ECO8A ;  C4ZWA2, CITG_ECOBW ;
DR   A7ZXP0, CITG_ECOHS ;  A1A8P2, CITG_ECOK1 ;  Q0TK59, CITG_ECOL5 ;
DR   Q8FK04, CITG_ECOL6 ;  B1IYJ3, CITG_ECOLC ;  P77231, CITG_ECOLI ;
DR   B7N9L9, CITG_ECOLU ;  B6I0S2, CITG_ECOSE ;  B1LKK5, CITG_ECOSM ;
DR   Q1REU9, CITG_ECOUT ;  Q6D425, CITG_ERWCT ;  B7LWM0, CITG_ESCF3 ;
DR   O30827, CITG_HAEDU ;  P45414, CITG_KLEPN ;  Q88XT4, CITG_LACPL ;
DR   C6DF89, CITG_PECCP ;  Q6LPV0, CITG_PHOPR ;  Q21VT1, CITG_RHOFD ;
DR   A9MKG0, CITG_SALAR ;  B5RG98, CITG_SALG2 ;  B2TTH6, CITG_SHIB3 ;
DR   Q0T703, CITG_SHIF8 ;  Q7UDF6, CITG_SHIFL ;  Q3Z4I0, CITG_SHISS ;
DR   C0M6C1, CITG_STRE4 ;  B4U2X5, CITG_STREM ;  Q8DUC9, CITG_STRMU ;
DR   P58159, CITG_STRP1 ;  P0DA30, CITG_STRP3 ;  Q5XC41, CITG_STRP6 ;
DR   Q8P102, CITG_STRP8 ;  Q1JGR7, CITG_STRPD ;  Q1J6I6, CITG_STRPF ;
DR   A2REF2, CITG_STRPG ;  Q48TH6, CITG_STRPM ;  P0DA31, CITG_STRPQ ;
DR   B5XLM1, CITG_STRPZ ;  C0MFF6, CITG_STRS7 ;  Q9KTT7, CITG_VIBCH ;
DR   C3LT54, CITG_VIBCM ;  P44458, CITXG_HAEIN;  O53080, CITXG_LEUMC;
DR   Q9RLT3, CITXG_WEIPA;  Q9RGM3, MDCB_ACICA ;  C1DNP5, MDCB_AZOVD ;
DR   P71422, MDCB_KLEPN ;  O06922, MDCB_MALRU ;  Q48PD2, MDCB_PSE14 ;
DR   A6UY04, MDCB_PSEA7 ;  B7V2C0, MDCB_PSEA8 ;  Q02UM6, MDCB_PSEAB ;
DR   Q9I6S9, MDCB_PSEAE ;  Q4K4F6, MDCB_PSEF5 ;  Q3K5B6, MDCB_PSEPF ;
DR   Q9Z452, MDCB_PSEPU ;  Q87V55, MDCB_PSESM ;  Q4ZZA9, MDCB_PSEU2 ;
DR   A4VRZ0, MDCB_PSEU5 ;
//
ID   2.7.8.26
DE   Adenosylcobinamide-GDP ribazoletransferase.
AN   Cobalamin (5'-phosphate) synthase.
AN   Cobalamin synthase.
AN   Cobalamin-5'-phosphate synthase.
CA   (1) Adenosylcobinamide-GDP + alpha-ribazole = GMP + adenosylcobalamin.
CA   (2) Adenosylcobinamide-GDP + alpha-ribazole 5'-phosphate = GMP +
CA   adenosylcobalamin 5'-phosphate.
CC   -!- In Salmonella typhimurium LT2, under anaerobic conditions, CobU
CC       (EC 2.7.7.62 and EC 2.7.1.156), CobT (EC 2.4.2.21),
CC       CobC (EC 3.1.3.73) and CobS (EC 2.7.8.26) catalyze reactions in the
CC       nucleotide loop assembly pathway, which convert adenosylcobinamide
CC       (AdoCbi) into adenosylcobalamin (AdoCbl).
CC   -!- CobT and CobC are involved in 5,6-dimethylbenzimidazole activation
CC       whereby 5,6-dimethylbenzimidazole is converted to its riboside,
CC       alpha-ribazole.
CC   -!- The second branch of the nucleotide loop assembly pathway is the
CC       cobinamide (Cbi) activation branch where AdoCbi or
CC       adenosylcobinamide-phosphate is converted to the activated
CC       intermediate AdoCbi-GDP by the bifunctional enzyme CobU.
CC   -!- CobS catalyzes the final step in adenosylcobalamin biosynthesis,
CC       which is the condensation of AdoCbi-GDP with alpha-ribazole to yield
CC       adenosylcobalamin.
//
ID   2.7.8.27
DE   Sphingomyelin synthase.
AN   Phosphatidylcholine:ceramide cholinephosphotransferase.
AN   SM synthase.
CA   A ceramide + a phosphatidylcholine = a sphingomyelin + a 1,2-diacyl-
CA   sn-glycerol.
CC   -!- The reaction can occur in both directions.
CC   -!- Occupies a central position in sphingolipid and glycerophospholipid
CC       metabolism.
CC   -!- Up- and down-regulation of its activity has been linked to mitogenic
CC       and pro-apoptotic signaling in a variety of mammalian cell types.
CC   -!- Unlike EC 2.7.8.3 CDP-choline cannot replace phosphatidylcholine as
CC       the donor of the phosphocholine moiety of sphingomyelin.
DR   Q9U3D4, SMS1_CAEEL ;  Q7T3T4, SMS1_CHICK ;  Q86VZ5, SMS1_HUMAN ;
DR   Q8VCQ6, SMS1_MOUSE ;  A0AAS4, SMS1_PIG   ;  Q7TSX5, SMS1_RAT   ;
DR   Q20735, SMS2_CAEEL ;  Q8NHU3, SMS2_HUMAN ;  Q4R763, SMS2_MACFA ;
DR   Q9D4B1, SMS2_MOUSE ;  Q4JM44, SMS2_RAT   ;  Q965Q4, SMS3_CAEEL ;
//
ID   2.7.8.28
DE   2-phospho-L-lactate transferase.
CA   (2S)-lactyl-2-diphospho-5'-guanosine + 7,8-didemethyl-8-hydroxy-5-
CA   deazariboflavin = guanosine 5'-phosphate + coenzyme F420-0.
CC   -!- This enzyme is involved in the biosynthesis of coenzyme F420,
CC       a redox-active cofactor found in all methanogenic archaea, as well as
CC       some eubacteria.
DR   O29345, COFD_ARCFU ;  Q5V5R9, COFD_HALMA ;  B0R5L0, COFD_HALS3 ;
DR   Q9HPX4, COFD_HALSA ;  Q8TST1, COFD_METAC ;  A7I4I0, COFD_METB6 ;
DR   Q46C16, COFD_METBF ;  Q12W53, COFD_METBU ;  Q2FRU9, COFD_METHJ ;
DR   Q58653, COFD_METJA ;  Q8TVA3, COFD_METKA ;  A2SPS3, COFD_METLZ ;
DR   A4FZ98, COFD_METM5 ;  A9A6P5, COFD_METM6 ;  A6VJ39, COFD_METM7 ;
DR   Q8PVT6, COFD_METMA ;  Q6M067, COFD_METMP ;  B8GF42, COFD_METPE ;
DR   O27097, COFD_METTH ;  A6US17, COFD_METVS ;  A0QKC7, COFD_MYCA1 ;
DR   Q7TWV4, COFD_MYCBO ;  A1KNR3, COFD_MYCBP ;  C1AH35, COFD_MYCBT ;
DR   Q9CCK1, COFD_MYCLE ;  B2HEN2, COFD_MYCMM ;  Q73UJ4, COFD_MYCPA ;
DR   A0QTG2, COFD_MYCS2 ;  A3PW85, COFD_MYCSJ ;  A1UCJ5, COFD_MYCSK ;
DR   Q1BCE8, COFD_MYCSS ;  A5U7T5, COFD_MYCTA ;  P96866, COFD_MYCTU ;
DR   A0PRG8, COFD_MYCUA ;  Q3IRY6, COFD_NATPD ;  Q5YQR9, COFD_NOCFA ;
DR   Q75UN1, COFD_STRAU ;  Q82DE2, COFD_STRAW ;  Q9KZK9, COFD_STRCO ;
DR   B1VUV4, COFD_STRGG ;  Q47LX2, COFD_THEFY ;
//
ID   2.7.8.29
DE   L-serine-phosphatidylethanolamine phosphatidyltransferase.
AN   Phosphatidylserine synthase 2.
CA   L-1-phosphatidylethanolamine + L-serine = L-1-phosphatidylserine +
CA   ethanolamine.
CC   -!- This mammalian enzyme catalyzes an exchange reaction in which the
CC       polar head group of phosphatidylethanolamine is replaced by L-serine.
//
ID   2.7.8.30
DE   Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase.
AN   Ara4FN transferase.
AN   Polymyxin resistance protein PmrF.
AN   Undecaprenyl-phosphate Ara4FN transferase.
CA   UDP-4-deoxy-4-formamido-beta-L-arabinose + di-trans,octa-cis-undecaprenyl
CA   phosphate = UDP + 4-deoxy-4-formamido-alpha-L-arabinose di-trans,octa-
CA   cis-undecaprenyl phosphate.
CC   -!- The enzyme shows no activity with UDP-4-amino-4-deoxy-beta-L-
CC       arabinose.
CC   -!- Formerly EC 2.7.8.n1.
DR   A0KGY7, ARNC_AERHH ;  A4SQW8, ARNC_AERS4 ;  A7ZP72, ARNC_ECO24 ;
DR   B7UFR6, ARNC_ECO27 ;  B7MG21, ARNC_ECO45 ;  B7LAR9, ARNC_ECO55 ;
DR   Q8XDZ5, ARNC_ECO57 ;  B5YX45, ARNC_ECO5E ;  B7NNT3, ARNC_ECO7I ;
DR   B7MXT5, ARNC_ECO81 ;  B7M5T6, ARNC_ECO8A ;  C4ZU96, ARNC_ECOBW ;
DR   B1X8W7, ARNC_ECODH ;  A8A2C1, ARNC_ECOHS ;  A1ADA6, ARNC_ECOK1 ;
DR   Q0TFI8, ARNC_ECOL5 ;  Q8FFM2, ARNC_ECOL6 ;  B1IXT3, ARNC_ECOLC ;
DR   P77757, ARNC_ECOLI ;  B7N5L9, ARNC_ECOLU ;  B6I7J7, ARNC_ECOSE ;
DR   B1LLK8, ARNC_ECOSM ;  Q1R9G1, ARNC_ECOUT ;  C5BDQ5, ARNC_EDWI9 ;
DR   A4WAM4, ARNC_ENT38 ;  Q6D2F0, ARNC_ERWCT ;  B2VBJ0, ARNC_ERWT9 ;
DR   B7LM77, ARNC_ESCF3 ;  B5XTK8, ARNC_KLEP3 ;  A6TF99, ARNC_KLEP7 ;
DR   C6DAW6, ARNC_PECCP ;  Q7N3Q6, ARNC_PHOLL ;  B4ETL6, ARNC_PROMH ;
DR   Q48HZ2, ARNC_PSE14 ;  A6V1P1, ARNC_PSEA7 ;  B7VBN3, ARNC_PSEA8 ;
DR   Q02R24, ARNC_PSEAB ;  Q9HY64, ARNC_PSEAE ;  Q4KC83, ARNC_PSEF5 ;
DR   C3KAD3, ARNC_PSEFS ;  Q3KCC2, ARNC_PSEPF ;  Q4ZSZ3, ARNC_PSEU2 ;
DR   B5EZH7, ARNC_SALA4 ;  Q57M56, ARNC_SALCH ;  B5FNT8, ARNC_SALDC ;
DR   B5R271, ARNC_SALEP ;  B5RCC3, ARNC_SALG2 ;  B4TBG5, ARNC_SALHS ;
DR   B4SYX0, ARNC_SALNS ;  Q5PNA5, ARNC_SALPA ;  A9N5B3, ARNC_SALPB ;
DR   C0Q070, ARNC_SALPC ;  B5BCP7, ARNC_SALPK ;  B4TPI1, ARNC_SALSV ;
DR   Q8Z541, ARNC_SALTI ;  O52324, ARNC_SALTY ;  A8GDR6, ARNC_SERP5 ;
DR   A8FRR3, ARNC_SHESH ;  Q31YK3, ARNC_SHIBS ;  Q32DT4, ARNC_SHIDS ;
DR   Q0T2M9, ARNC_SHIF8 ;  Q7UC63, ARNC_SHIFL ;  Q3YZV2, ARNC_SHISS ;
DR   Q2NRV6, ARNC_SODGM ;  Q8D342, ARNC_WIGBR ;  A1JPP5, ARNC_YERE8 ;
DR   Q1C741, ARNC_YERPA ;  B2K5L4, ARNC_YERPB ;  Q8ZDX7, ARNC_YERPE ;
DR   A9R094, ARNC_YERPG ;  Q1CIH6, ARNC_YERPN ;  A4TIM3, ARNC_YERPP ;
DR   Q93PD9, ARNC_YERPS ;  B1JJ29, ARNC_YERPY ;
//
ID   2.7.8.31
DE   Undecaprenyl-phosphate glucose phosphotransferase.
AN   Undecaprenylphosphate glucosylphosphate transferase.
CA   UDP-glucose + di-trans,octa-cis-undecaprenyl phosphate = UMP + alpha-D-
CA   glucopyranosyl-diphospho-di-trans,octa-cis-undecaprenol.
CC   -!- The enzyme is involved in biosynthesis of xanthan.
//
ID   2.7.8.32
DE   3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose
DE   xylosylphosphotransferase.
AN   XPT1.
CA   UDP-xylose + 3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose = UMP +
CA   3-O-(6-O-alpha-D-xylosylphospho-alpha-D-mannopyranosyl)-alpha-D-
CA   mannopyranose.
CF   Manganese.
CC   -!- The enzyme is specific for mannose as an acceptor but is flexible as
CC       to the structural context of the mannosyl disaccharide.
//
ID   2.7.8.33
DE   UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase.
AN   Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate
AN   transferase.
CA   UDP-N-acetyl-D-glucosamine + di-trans,octa-cis-undecaprenyl phosphate =
CA   UMP + N-acetyl-D-glucosaminyldiphospho-di-trans,octa-cis-undecaprenol.
CC   -!- This enzyme catalyzes the synthesis of di-trans,octa-
CC       cis-undecaprenyl-N-acetyl-D-glucosaminyl diphosphate (i.e. lipid I),
CC       an essential lipid intermediate for the biosynthesis of various
CC       bacterial cell envelope components.
CC   -!- The enzyme also initiates the biosynthesis of enterobacterial common
CC       antigen and O-antigen lipopolysaccharide in certain Escherichia coli
CC       strains, including K-12 and of teichoic acid in certain Gram-positive
CC       bacteria.
CC   -!- Formerly EC 2.7.8.n2.
DR   O34753, TAGO_BACSU ;  Q8XAS7, WECA_ECO57 ;  P0AC79, WECA_ECOL6 ;
DR   P0AC78, WECA_ECOLI ;  P45341, WECA_HAEIN ;  P45830, WECA_MYCLE ;
DR   Q10606, WECA_MYCTU ;  Q9CNG8, WECA_PASMU ;  Q8Z386, WECA_SALTI ;
DR   Q9L6R7, WECA_SALTY ;  P0AC80, WECA_SHIFL ;  Q9X1N5, WECA_THEMA ;
DR   Q8ZAE1, WECA_YERPE ;
//
ID   2.7.8.n1
DE   Transferred entry: 2.7.8.30.
//
ID   2.7.8.n2
DE   Transferred entry: 2.7.8.33.
//
ID   2.7.9.1
DE   Pyruvate, phosphate dikinase.
AN   PPDK.
AN   Pyruvate,orthophosphate dikinase.
AN   Pyruvate,phosphate dikinase.
CA   ATP + pyruvate + phosphate = AMP + phosphoenolpyruvate + diphosphate.
PR   PROSITE; PDOC00527;
DR   O23404, PPDK1_ARATH;  P11155, PPDK1_MAIZE;  Q6AVA8, PPDK1_ORYSJ;
DR   Q42368, PPDK2_MAIZE;  Q75KR1, PPDK2_ORYSJ;  P22983, PPDK_CLOSY ;
DR   P37213, PPDK_ENTHI ;  Q39735, PPDK_FLABI ;  Q39734, PPDK_FLABR ;
DR   Q42736, PPDK_FLAPR ;  P22221, PPDK_FLATR ;  P51776, PPDK_GIAIN ;
DR   Q42910, PPDK_MESCR ;  Q59754, PPDK_RHIME ;  Q1RH78, PPDK_RICBR ;
DR   Q92HI8, PPDK_RICCN ;  Q4ULI7, PPDK_RICFE ;  Q9ZD55, PPDK_RICPR ;
DR   Q68WP2, PPDK_RICTY ;  O83728, PPDK_TREPA ;
//
ID   2.7.9.2
DE   Pyruvate, water dikinase.
AN   Phosphoenolpyruvate synthase.
AN   Pyruvate,water dikinase.
CA   ATP + pyruvate + H(2)O = AMP + phosphoenolpyruvate + phosphate.
CF   Manganese.
PR   PROSITE; PDOC00527;
DR   Q9YEC5, PPSA_AERPE ;  O67899, PPSA_AQUAE ;  O29548, PPSA_ARCFU ;
DR   O83026, PPSA_DEIRA ;  P23538, PPSA_ECOLI ;  O54457, PPSA_ENTAG ;
DR   Q9ZMV4, PPSA_HELPJ ;  P56070, PPSA_HELPY ;  Q57962, PPSA_METJA ;
DR   O27190, PPSA_METTH ;  Q9K0I2, PPSA_NEIMB ;  Q9V2H7, PPSA_PYRAB ;
DR   P42850, PPSA_PYRFU ;  O57830, PPSA_PYRHO ;  P46893, PPSA_STAMF ;
DR   Q55905, PPSA_SYNY3 ;
//
ID   2.7.9.3
DE   Selenide, water dikinase.
AN   Selenide,water dikinase.
AN   Selenium donor protein.
AN   Selenophosphate synthase.
AN   Selenophosphate synthetase.
CA   ATP + selenide + H(2)O = AMP + selenophosphate + phosphate.
CF   Magnesium.
DR   Q9L4E1, SELD1_EUBAC;  Q9L473, SELD2_EUBAC;  A3MZ45, SELD_ACTP2 ;
DR   A0KKE7, SELD_AERHH ;  A4SMM1, SELD_AERS4 ;  A8MHJ6, SELD_ALKOO ;
DR   O67139, SELD_AQUAE ;  A8EUZ4, SELD_ARCB4 ;  Q6MK42, SELD_BDEBA ;
DR   Q7WE97, SELD_BORBR ;  B1Z181, SELD_BURA4 ;  B1K568, SELD_BURCC ;
DR   B4EJQ7, SELD_BURCJ ;  Q63NL2, SELD_BURPS ;  Q13R51, SELD_BURXL ;
DR   O62461, SELD_CAEEL ;  Q9PMF9, SELD_CAMJE ;  Q5HSS7, SELD_CAMJR ;
DR   Q3AAF7, SELD_CARHZ ;  B2V0F0, SELD_CLOBA ;  B2TKP6, SELD_CLOBB ;
DR   Q182I1, SELD_CLOD6 ;  A9KPW1, SELD_CLOPH ;  Q488J7, SELD_COLP3 ;
DR   Q47H71, SELD_DECAR ;  B8FWU2, SELD_DESHD ;  Q24NA9, SELD_DESHY ;
DR   Q72CF1, SELD_DESVH ;  B8DNL1, SELD_DESVM ;  A1VE87, SELD_DESVV ;
DR   Q94497, SELD_DICDI ;  A7ZMN3, SELD_ECO24 ;  P66794, SELD_ECO57 ;
DR   A8A0V7, SELD_ECOHS ;  Q0TH64, SELD_ECOL5 ;  P66793, SELD_ECOL6 ;
DR   P16456, SELD_ECOLI ;  A4W9I2, SELD_ENT38 ;  A7MNU8, SELD_ENTS8 ;
DR   C4ZDB0, SELD_EUBR3 ;  B5EBG1, SELD_GEOBB ;  B3E7F7, SELD_GEOLS ;
DR   Q39RJ9, SELD_GEOMG ;  Q74FK1, SELD_GEOSL ;  C6E5Z5, SELD_GEOSM ;
DR   Q7VNG0, SELD_HAEDU ;  Q4QNZ0, SELD_HAEI8 ;  A5UG02, SELD_HAEIG ;
DR   P43911, SELD_HAEIN ;  P60819, SELD_METJA ;  Q8TVM0, SELD_METKA ;
DR   P60820, SELD_METMP ;  B8ES21, SELD_METSB ;  Q1DAT6, SELD_MYXXD ;
DR   Q0AFI6, SELD_NITEC ;  Q9CMM8, SELD_PASMU ;  A1APP9, SELD_PELPD ;
DR   Q7N406, SELD_PHOLL ;  Q6LP05, SELD_PHOPR ;  B2RLG7, SELD_PORG3 ;
DR   Q7MU19, SELD_PORGI ;  Q9I383, SELD_PSEAE ;  Q9AQI4, SELD_PSEOC ;
DR   P59392, SELD_PSEPK ;  Q889F7, SELD_PSESM ;  Q931D0, SELD_RHIME ;
DR   Q8Z6F4, SELD_SALTI ;  Q8ZPV5, SELD_SALTY ;  B8EBM9, SELD_SHEB2 ;
DR   A3DA84, SELD_SHEB5 ;  A6WHQ5, SELD_SHEB8 ;  A9KW79, SELD_SHEB9 ;
DR   Q8EK99, SELD_SHEON ;  A4YBB9, SELD_SHEPC ;  A0KRK1, SELD_SHESA ;
DR   Q0HNW1, SELD_SHESM ;  Q0I0C9, SELD_SHESR ;  A1RP94, SELD_SHESW ;
DR   Q321Q8, SELD_SHIBS ;  Q32GA8, SELD_SHIDS ;  Q0T4X1, SELD_SHIF8 ;
DR   P59393, SELD_SHIFL ;  Q3Z2B0, SELD_SHISS ;  Q30RE1, SELD_SULDN ;
DR   A6QBB7, SELD_SULNB ;  Q8R8W3, SELD_THETN ;  Q73JP8, SELD_TREDE ;
DR   Q8ZEK1, SELD_YERPE ;  Q66AP0, SELD_YERPS ;  Q0VC82, SPS1_BOVIN ;
DR   Q7ZW38, SPS1_DANRE ;  O18373, SPS1_DROME ;  P49903, SPS1_HUMAN ;
DR   Q8BH69, SPS1_MOUSE ;  Q5RF87, SPS1_PONAB ;  Q6PF47, SPS1_XENLA ;
DR   Q6GL12, SPS1_XENTR ;  Q9VKY8, SPS2_DROME ;  Q99611, SPS2_HUMAN ;
DR   P97364, SPS2_MOUSE ;  A1YIZ1, SPS2_PIG   ;
//
ID   2.7.9.4
DE   Alpha-glucan, water dikinase.
AN   Alpha-glucan,water dikinase.
AN   Starch-related R1 protein.
CA   ATP + alpha-glucan + H(2)O = AMP + phospho-alpha-glucan + phosphate.
CF   Magnesium.
CC   -!- ATP appears to be the only phosphate donor.
CC   -!- No activity could be detected using GTP, UTP, phosphoenolpyruvate or
CC       diphosphate.
CC   -!- The protein phosphorylates glucans exclusively at O-6 of glucosyl
CC       residues.
CC   -!- The protein phosphorylates itself with the beta-phosphate of ATP,
CC       which is then transferred to the glucan.
DR   Q9SAC6, GWD1_ARATH ;  Q8LPT9, GWD1_CITRE ;  Q9AWA5, GWD1_SOLTU ;
DR   Q9STV0, GWD2_ARATH ;
//
ID   2.7.9.5
DE   Phosphoglucan, water dikinase.
CA   ATP + (phospho-alpha-glucan) + H(2)O = AMP + O-phospho-(phospho-alpha-
CA   glucan) + phosphate.
CC   -!- The enzyme phosphorylates granular starch that has previously been
CC       phosphorylated by EC 2.7.9.4; there is no activity with
CC       unphosphorylated glucans.
CC   -!- It transfers the beta-phosphate of ATP to the phosphoglucan, whereas
CC       the gamma-phosphate is transferred to water.
CC   -!- In contrast to EC 2.7.9.4, which phosphorylates the glucose groups in
CC       glucans predominantly on O-6, this enzyme phosphorylates glucose
CC       groups in phosphorylated starch predominantly on O-3.
CC   -!- The protein phosphorylates itself with the beta-phosphate of ATP,
CC       which is then transferred to the glucan.
DR   Q6ZY51, PWD_ARATH  ;  Q2QTC2, PWD_ORYSJ  ;
//
ID   2.7.10.1
DE   Receptor protein-tyrosine kinase.
AN   Receptor protein tyrosine kinase.
CA   ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
CC   -!- The receptor protein-tyrosine kinases, which can be defined as having
CC       a transmembrane domain, are a large and diverse multigene family
CC       found only in metazoans.
CC   -!- In the human genome, 58 receptor-type protein-tyrosine kinases have
CC       been identified and these are distributed into 20 subfamilies.
CC   -!- Formerly EC 2.7.1.112.
PR   PROSITE; PDOC00100;
DR   P13368, 7LESS_DROME;  P20806, 7LESS_DROVI;  Q54N73, 7TMK1_DICDI;
DR   Q9UM73, ALK_HUMAN  ;  P97793, ALK_MOUSE  ;  Q94F62, BAK1_ARATH ;
DR   O22476, BRI1_ARATH ;  Q9LJF3, BRL3_ARATH ;  Q9VBW3, CAD96_DROME;
DR   P79750, CSF11_TAKRU;  Q8UVR8, CSF12_TAKRU;  Q9I8N6, CSF1R_DANRE;
DR   P13369, CSF1R_FELCA;  P07333, CSF1R_HUMAN;  P09581, CSF1R_MOUSE;
DR   Q00495, CSF1R_RAT  ;  Q08345, DDR1_HUMAN ;  Q03146, DDR1_MOUSE ;
DR   Q7YR43, DDR1_PANTR ;  Q63474, DDR1_RAT   ;  Q16832, DDR2_HUMAN ;
DR   Q62371, DDR2_MOUSE ;  P0CY46, EGFR_APIME ;  P13387, EGFR_CHICK ;
DR   P04412, EGFR_DROME ;  P00533, EGFR_HUMAN ;  P55245, EGFR_MACMU ;
DR   Q01279, EGFR_MOUSE ;  Q10656, EGL15_CAEEL;  O13148, EPA4A_DANRE;
DR   Q91845, EPA4A_XENLA;  Q91694, EPA4B_XENLA;  Q91571, EPB1A_XENLA;
DR   Q91736, EPB1B_XENLA;  P21709, EPHA1_HUMAN;  Q60750, EPHA1_MOUSE;
DR   P29317, EPHA2_HUMAN;  Q1KL86, EPHA2_MACFA;  Q03145, EPHA2_MOUSE;
DR   P29318, EPHA3_CHICK;  O13146, EPHA3_DANRE;  P29320, EPHA3_HUMAN;
DR   P29319, EPHA3_MOUSE;  O08680, EPHA3_RAT  ;  Q07496, EPHA4_CHICK;
DR   P54764, EPHA4_HUMAN;  Q03137, EPHA4_MOUSE;  P54755, EPHA5_CHICK;
DR   P54756, EPHA5_HUMAN;  Q60629, EPHA5_MOUSE;  P54757, EPHA5_RAT  ;
DR   Q9UF33, EPHA6_HUMAN;  Q62413, EPHA6_MOUSE;  P54758, EPHA6_RAT  ;
DR   O42422, EPHA7_CHICK;  Q15375, EPHA7_HUMAN;  Q61772, EPHA7_MOUSE;
DR   P54759, EPHA7_RAT  ;  P29322, EPHA8_HUMAN;  O09127, EPHA8_MOUSE;
DR   P29321, EPHA8_RAT  ;  Q5JZY3, EPHAA_HUMAN;  Q8BYG9, EPHAA_MOUSE;
DR   Q07494, EPHB1_CHICK;  P54762, EPHB1_HUMAN;  Q8CBF3, EPHB1_MOUSE;
DR   P09759, EPHB1_RAT  ;  P28693, EPHB2_CHICK;  Q90344, EPHB2_COTJA;
DR   P29323, EPHB2_HUMAN;  P54763, EPHB2_MOUSE;  Q07498, EPHB3_CHICK;
DR   O13147, EPHB3_DANRE;  P54753, EPHB3_HUMAN;  P54754, EPHB3_MOUSE;
DR   Q91735, EPHB3_XENLA;  P54760, EPHB4_HUMAN;  P54761, EPHB4_MOUSE;
DR   Q07497, EPHB5_CHICK;  O18735, ERBB2_CANFA;  P04626, ERBB2_HUMAN;
DR   Q60553, ERBB2_MESAU;  P70424, ERBB2_MOUSE;  P06494, ERBB2_RAT  ;
DR   P21860, ERBB3_HUMAN;  Q61526, ERBB3_MOUSE;  Q5RB22, ERBB3_PONAB;
DR   Q62799, ERBB3_RAT  ;  Q15303, ERBB4_HUMAN;  Q61527, ERBB4_MOUSE;
DR   Q62956, ERBB4_RAT  ;  P00534, ERBB_ALV   ;  P00535, ERBB_AVIER ;
DR   P11273, ERBB_AVIEU ;  P21804, FGFR1_CHICK;  Q07407, FGFR1_DROME;
DR   Q8MY86, FGFR1_DUGJA;  P11362, FGFR1_HUMAN;  P16092, FGFR1_MOUSE;
DR   Q91285, FGFR1_PLEWA;  Q04589, FGFR1_RAT  ;  P22182, FGFR1_XENLA;
DR   P18461, FGFR2_CHICK;  Q8JG38, FGFR2_DANRE;  Q09147, FGFR2_DROME;
DR   Q8MY85, FGFR2_DUGJA;  P21802, FGFR2_HUMAN;  P21803, FGFR2_MOUSE;
DR   Q91147, FGFR2_NOTVI;  Q91286, FGFR2_PLEWA;  Q03364, FGFR2_XENLA;
DR   P18460, FGFR3_CHICK;  Q9I8X3, FGFR3_DANRE;  P22607, FGFR3_HUMAN;
DR   Q61851, FGFR3_MOUSE;  Q91287, FGFR3_PLEWA;  O42127, FGFR3_XENLA;
DR   Q90330, FGFR4_COTCO;  Q90413, FGFR4_DANRE;  P22455, FGFR4_HUMAN;
DR   Q03142, FGFR4_MOUSE;  Q91288, FGFR4_PLEWA;  Q498D6, FGFR4_RAT  ;
DR   Q91743, FGFR4_XENLA;  Q4H3K6, FGFR_CIOIN ;  Q95YM9, FGFR_HALRO ;
DR   Q86PM4, FGFR_HYDVU ;  Q26614, FGFR_STRPU ;  Q90Z00, FGR1A_DANRE;
DR   P36888, FLT3_HUMAN ;  Q00342, FLT3_MOUSE ;  Q25197, HTK7_HYDVU ;
DR   Q05688, IGF1R_BOVIN;  P08069, IGF1R_HUMAN;  Q60751, IGF1R_MOUSE;
DR   Q29000, IGF1R_PIG  ;  P24062, IGF1R_RAT  ;  O73798, IGF1R_XENLA;
DR   O02466, ILPR_BRALA ;  P14617, INSRR_CAVPO;  P14616, INSRR_HUMAN;
DR   Q9WTL4, INSRR_MOUSE;  Q64716, INSRR_RAT  ;  Q93105, INSR_AEDAE ;
DR   Q968Y9, INSR_CAEEL ;  P09208, INSR_DROME ;  P06213, INSR_HUMAN ;
DR   Q28516, INSR_MACMU ;  P15208, INSR_MOUSE ;  P15127, INSR_RAT   ;
DR   Q9PVZ4, INSR_XENLA ;  P00545, KFMS_FSVMD ;  P34891, KIN15_CAEEL;
DR   P34892, KIN16_CAEEL;  Q8JFR5, KITA_DANRE ;  P43481, KIT_BOVIN  ;
DR   Q76II0, KIT_CALJA  ;  O97799, KIT_CANFA  ;  Q28317, KIT_CAPHI  ;
DR   Q08156, KIT_CHICK  ;  Q28889, KIT_FELCA  ;  P04048, KIT_FSVHZ  ;
DR   P10721, KIT_HUMAN  ;  P05532, KIT_MOUSE  ;  Q2HWD6, KIT_PIG    ;
DR   Q8AXC6, KIT_TAKRU  ;  Q91909, KIT_XENLA  ;  P24348, LET23_CAEEL;
DR   P29376, LTK_HUMAN  ;  P08923, LTK_MOUSE  ;  Q12866, MERTK_HUMAN;
DR   Q60805, MERTK_MOUSE;  P57097, MERTK_RAT  ;  Q07DV8, MET_AOTNA  ;
DR   Q00PJ8, MET_ATEAB  ;  Q09YL1, MET_ATEGE  ;  Q769I5, MET_BOVIN  ;
DR   Q2QLG5, MET_CALJA  ;  Q2QLC0, MET_CALMO  ;  Q75ZY9, MET_CANFA  ;
DR   Q2IBA6, MET_CHLAE  ;  Q07DZ1, MET_COLGU  ;  Q07E48, MET_DASNO  ;
DR   A1X150, MET_ECHTE  ;  Q2IBG7, MET_EULMM  ;  A0M8S8, MET_FELCA  ;
DR   Q2IBF2, MET_GORGO  ;  Q2QLA9, MET_HORSE  ;  P08581, MET_HUMAN  ;
DR   Q108U6, MET_LOXAF  ;  Q2QL89, MET_MICMU  ;  P16056, MET_MOUSE  ;
DR   Q09YK0, MET_MUNMU  ;  Q07E24, MET_MUSPF  ;  Q07E37, MET_NEONE  ;
DR   Q07DY1, MET_NOMLE  ;  Q07E01, MET_ORNAN  ;  Q2QLH6, MET_OTOGA  ;
DR   Q2QLF1, MET_PANTR  ;  A0M8R7, MET_PAPAN  ;  Q2QLE0, MET_PIG    ;
DR   Q2IBD8, MET_PONAB  ;  Q09YN5, MET_RABIT  ;  P97523, MET_RAT    ;
DR   Q2IBC0, MET_RHIFE  ;  Q09YH7, MET_SAIBB  ;  Q09YI9, MET_SHEEP  ;
DR   Q25410, MIPR_LYMST ;  Q8AXY6, MUSK_CHICK ;  O15146, MUSK_HUMAN ;
DR   Q61006, MUSK_MOUSE ;  Q62838, MUSK_RAT   ;  Q91009, NTRK1_CHICK;
DR   P04629, NTRK1_HUMAN;  Q3UFB7, NTRK1_MOUSE;  P35739, NTRK1_RAT  ;
DR   Q91987, NTRK2_CHICK;  Q16620, NTRK2_HUMAN;  P15209, NTRK2_MOUSE;
DR   Q63604, NTRK2_RAT  ;  Q91044, NTRK3_CHICK;  Q16288, NTRK3_HUMAN;
DR   Q5IFJ9, NTRK3_MACFA;  Q6VNS1, NTRK3_MOUSE;  Q5IS37, NTRK3_PANTR;
DR   P24786, NTRK3_PIG  ;  Q03351, NTRK3_RAT  ;  Q5IS82, NTRK3_SAIBB;
DR   Q9PUF6, PGFRA_CHICK;  Q9DE49, PGFRA_DANRE;  P16234, PGFRA_HUMAN;
DR   P26618, PGFRA_MOUSE;  P20786, PGFRA_RAT  ;  Q8AXC7, PGFRA_TAKRU;
DR   P26619, PGFRA_XENLA;  Q6QNF3, PGFRB_CANFA;  P09619, PGFRB_HUMAN;
DR   P05622, PGFRB_MOUSE;  Q05030, PGFRB_RAT  ;  P79749, PGFRB_TAKRU;
DR   P07949, RET_HUMAN  ;  P35546, RET_MOUSE  ;  P47735, RLK5_ARATH ;
DR   Q9LIG2, RLK6_ARATH ;  Q9FN94, RLK7_ARATH ;  Q04912, RON_HUMAN  ;
DR   Q62190, RON_MOUSE  ;  Q24488, ROR1_DROME ;  Q01973, ROR1_HUMAN ;
DR   Q9Z139, ROR1_MOUSE ;  Q9V6K3, ROR2_DROME ;  Q01974, ROR2_HUMAN ;
DR   Q9Z138, ROR2_MOUSE ;  P00529, ROS_AVISU  ;  P08941, ROS_CHICK  ;
DR   P08922, ROS_HUMAN  ;  Q78DX7, ROS_MOUSE  ;  Q63132, ROS_RAT    ;
DR   P42159, RTK2_GEOCY ;  Q27324, RYK1_DROME ;  Q9V422, RYK2_DROME ;
DR   P33497, RYK_AVIR3  ;  P34925, RYK_HUMAN  ;  Q01887, RYK_MOUSE  ;
DR   Q9SKB2, SBIR1_ARATH;  Q94AG2, SERK1_ARATH;  Q9SKG5, SERK4_ARATH;
DR   Q06805, TIE1_BOVIN ;  O73792, TIE1_DANRE ;  P35590, TIE1_HUMAN ;
DR   Q06806, TIE1_MOUSE ;  Q06807, TIE2_BOVIN ;  O73791, TIE2_DANRE ;
DR   Q02763, TIE2_HUMAN ;  Q02858, TIE2_MOUSE ;  P18475, TORSO_DROME;
DR   O76997, TRK1_LYMST ;  Q98949, TYRO3_CHICK;  Q9YI66, TYRO3_DANRE;
DR   Q06418, TYRO3_HUMAN;  P55144, TYRO3_MOUSE;  P55146, TYRO3_RAT  ;
DR   Q8QFP9, TYRO3_XENLA;  A0JM20, TYRO3_XENTR;  P30530, UFO_HUMAN  ;
DR   Q00993, UFO_MOUSE  ;  O61460, VAB1_CAEEL ;  Q8QHL3, VGFR1_CHICK;
DR   P17948, VGFR1_HUMAN;  P35969, VGFR1_MOUSE;  P53767, VGFR1_RAT  ;
DR   P52583, VGFR2_COTJA;  Q5GIT4, VGFR2_DANRE;  P35968, VGFR2_HUMAN;
DR   P35918, VGFR2_MOUSE;  O08775, VGFR2_RAT  ;  P79701, VGFR3_COTCO;
DR   Q5MD89, VGFR3_DANRE;  P35916, VGFR3_HUMAN;  P35917, VGFR3_MOUSE;
DR   Q91ZT1, VGFR3_RAT  ;  Q8AXB3, VGFR4_DANRE;  P83097, WSCK_DROME ;
DR   P13388, XMRK_XIPMA ;  Q9C823, Y1523_ARATH;  O22938, Y2182_ARATH;
DR   Q19238, YS3J_CAEEL ;
//
ID   2.7.10.2
DE   Non-specific protein-tyrosine kinase.
AN   Cytoplasmic protein tyrosine kinase.
CA   ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
CC   -!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a
CC       transmembrane domain.
CC   -!- In the human genome, 32 non-specific protein-tyrosine kinases have
CC       been identified and these can be divided into 10 families.
CC   -!- Formerly EC 2.7.1.112.
PR   PROSITE; PDOC00100;
DR   P03949, ABL1_CAEEL ;  P00519, ABL1_HUMAN ;  P00520, ABL1_MOUSE ;
DR   P42684, ABL2_HUMAN ;  Q4JIM5, ABL2_MOUSE ;  P11681, ABL_CALVI  ;
DR   P00522, ABL_DROME  ;  P10447, ABL_FSVHY  ;  P00521, ABL_MLVAB  ;
DR   Q17R13, ACK1_BOVIN ;  Q07912, ACK1_HUMAN ;  O54967, ACK1_MOUSE ;
DR   Q5U2X5, ACK1_RAT   ;  A2BIL7, BAZ1B_DANRE;  Q9UIG0, BAZ1B_HUMAN;
DR   Q9Z277, BAZ1B_MOUSE;  A8DZJ1, BAZ1B_XENLA;  P51451, BLK_HUMAN  ;
DR   P16277, BLK_MOUSE  ;  P51813, BMX_HUMAN  ;  P97504, BMX_MOUSE  ;
DR   P08630, BTKL_DROME ;  Q8JH64, BTK_CHICK  ;  Q06187, BTK_HUMAN  ;
DR   P35991, BTK_MOUSE  ;  P39851, CAPB_STAAU ;  Q9AHD2, CPSD1_STRPN;
DR   Q54520, CPSD2_STRPN;  Q3K0T0, CPSD_STRA1 ;  Q04663, CPSD_STRA3 ;
DR   Q9AFI1, CPSD_STRA5 ;  P0C0T9, CPSD_STRAG ;  Q0VBZ0, CSK_BOVIN  ;
DR   P41239, CSK_CHICK  ;  P41240, CSK_HUMAN  ;  P41241, CSK_MOUSE  ;
DR   P32577, CSK_RAT    ;  Q00944, FAK1_CHICK ;  Q05397, FAK1_HUMAN ;
DR   P34152, FAK1_MOUSE ;  O35346, FAK1_RAT   ;  Q91738, FAK1_XENLA ;
DR   Q14289, FAK2_HUMAN ;  Q9QVP9, FAK2_MOUSE ;  P70600, FAK2_RAT   ;
DR   Q9TTY2, FER_CANFA  ;  P16591, FER_HUMAN  ;  P70451, FER_MOUSE  ;
DR   P09760, FER_RAT    ;  P14238, FES_FELCA  ;  P00542, FES_FSVGA  ;
DR   P00543, FES_FSVST  ;  P07332, FES_HUMAN  ;  P16879, FES_MOUSE  ;
DR   P00544, FGR_FSVGR  ;  P09769, FGR_HUMAN  ;  P14234, FGR_MOUSE  ;
DR   P00541, FPS_AVISP  ;  P18106, FPS_DROME  ;  P00530, FPS_FUJSV  ;
DR   P42685, FRK_HUMAN  ;  Q922K9, FRK_MOUSE  ;  Q62662, FRK_RAT    ;
DR   A0JNB0, FYN_BOVIN  ;  Q05876, FYN_CHICK  ;  P06241, FYN_HUMAN  ;
DR   P39688, FYN_MOUSE  ;  A1Y2K1, FYN_PIG    ;  Q62844, FYN_RAT    ;
DR   P13406, FYN_XENLA  ;  P27446, FYN_XIPHE  ;  P08631, HCK_HUMAN  ;
DR   Q95M30, HCK_MACFA  ;  P08103, HCK_MOUSE  ;  P50545, HCK_RAT    ;
DR   P53356, HTK16_HYDVU;  Q08881, ITK_HUMAN  ;  Q03526, ITK_MOUSE  ;
DR   Q09178, JAK1_CYPCA ;  O12990, JAK1_DANRE ;  P23458, JAK1_HUMAN ;
DR   P52332, JAK1_MOUSE ;  Q75R65, JAK2_CHICK ;  O60674, JAK2_HUMAN ;
DR   Q62120, JAK2_MOUSE ;  O19064, JAK2_PIG   ;  Q5RB23, JAK2_PONAB ;
DR   Q62689, JAK2_RAT   ;  P52333, JAK3_HUMAN ;  Q62137, JAK3_MOUSE ;
DR   Q63272, JAK3_RAT   ;  Q24592, JAK_DROME  ;  Q10925, KIN25_CAEEL;
DR   P34265, KIN31_CAEEL;  P43405, KSYK_HUMAN ;  P48025, KSYK_MOUSE ;
DR   Q00655, KSYK_PIG   ;  Q64725, KSYK_RAT   ;  Q5PXS1, LCK_AOTNA  ;
DR   P42683, LCK_CHICK  ;  P06239, LCK_HUMAN  ;  P06240, LCK_MOUSE  ;
DR   Q01621, LCK_RAT    ;  Q95KR7, LCK_SAISC  ;  P07948, LYN_HUMAN  ;
DR   P25911, LYN_MOUSE  ;  Q07014, LYN_RAT    ;  Q1DB00, MASK_MYXXD ;
DR   P42679, MATK_HUMAN ;  P41242, MATK_MOUSE ;  P41243, MATK_RAT   ;
DR   Q9H792, PEAK1_HUMAN;  Q69Z38, PEAK1_MOUSE;  Q9I7F7, PR2_DROME  ;
DR   Q8H1G6, PTI11_ARATH;  O49339, PTI12_ARATH;  B9DFG5, PTI13_ARATH;
DR   Q13882, PTK6_HUMAN ;  Q64434, PTK6_MOUSE ;  P18160, PYK1_DICDI ;
DR   P18161, PYK2_DICDI ;  Q9HUF7, RFAP_PSEAE ;  P23049, SEA_AVIET  ;
DR   Q86YV5, SG223_HUMAN;  Q571I4, SG223_MOUSE;  Q24145, SHARK_DROME;
DR   P42687, SPK1_DUGTI ;  P13115, SRC1_XENLA ;  P13116, SRC2_XENLA ;
DR   Q9V9J3, SRC42_DROME;  P00528, SRC64_DROME;  P15054, SRC_AVIS2  ;
DR   P00525, SRC_AVISR  ;  P14084, SRC_AVISS  ;  P14085, SRC_AVIST  ;
DR   P00523, SRC_CHICK  ;  P12931, SRC_HUMAN  ;  P05480, SRC_MOUSE  ;
DR   Q9WUD9, SRC_RAT    ;  P25020, SRC_RSVH1  ;  P00526, SRC_RSVP   ;
DR   P31693, SRC_RSVPA  ;  P00524, SRC_RSVSA  ;  P63185, SRC_RSVSE  ;
DR   P42686, SRK1_SPOLA ;  P42688, SRK2_SPOLA ;  P42689, SRK3_SPOLA ;
DR   P42690, SRK4_SPOLA ;  Q9H3Y6, SRMS_HUMAN ;  Q62270, SRMS_MOUSE ;
DR   P17713, STK_HYDVU  ;  Q6J9G0, STYK1_HUMAN;  Q6J9G1, STYK1_MOUSE;
DR   P42680, TEC_HUMAN  ;  P24604, TEC_MOUSE  ;  Q13470, TNK1_HUMAN ;
DR   Q99ML2, TNK1_MOUSE ;  P42681, TXK_HUMAN  ;  P42682, TXK_MOUSE  ;
DR   P29597, TYK2_HUMAN ;  Q9R117, TYK2_MOUSE ;  O36385, VG36_ALHV1 ;
DR   Q8AYK6, WEE1A_XENLA;  Q8QGV2, WEE1B_XENLA;  Q8L4H0, WEE1_ARATH ;
DR   P54350, WEE1_DROME ;  P30291, WEE1_HUMAN ;  P47810, WEE1_MOUSE ;
DR   Q6Z829, WEE1_ORYSJ ;  Q63802, WEE1_RAT   ;  P07527, WEE1_SCHPO ;
DR   P47817, WEE2A_XENLA;  O57473, WEE2B_XENLA;  Q6DFE0, WEE2C_XENLA;
DR   D2HHP1, WEE2_AILME ;  E2RSS3, WEE2_CANFA ;  E1BTE1, WEE2_CHICK ;
DR   Q1LX51, WEE2_DANRE ;  P0C1S8, WEE2_HUMAN ;  Q66JT0, WEE2_MOUSE ;
DR   A4PES0, WEE2_PIG   ;  A4QNA8, WEE2_XENTR ;  Q9LSC2, Y3589_ARATH;
DR   P00527, YES_AVISY  ;  Q28923, YES_CANFA  ;  P09324, YES_CHICK  ;
DR   P07947, YES_HUMAN  ;  Q04736, YES_MOUSE  ;  P10936, YES_XENLA  ;
DR   P27447, YES_XIPHE  ;  Q02977, YRK_CHICK  ;  Q54G28, YTYK1_DICDI;
DR   Q54R58, YTYK2_DICDI;  P71051, YVEL_BACSU ;  P96716, YWQD_BACSU ;
DR   Q11112, YX05_CAEEL ;  P43403, ZAP70_HUMAN;  P43404, ZAP70_MOUSE;
//
ID   2.7.11.1
DE   Non-specific serine/threonine protein kinase.
AN   Protein phosphokinase.
AN   Protein serine kinase.
AN   Protein serine-threonine kinase.
AN   Protein-serine kinase.
AN   Serine kinase.
AN   Serine protein kinase.
AN   Serine(threonine) protein kinase.
AN   Serine-specific protein kinase.
AN   Serine/threonine protein kinase.
AN   Threonine-specific protein kinase.
CA   ATP + a protein = ADP + a phosphoprotein.
CC   -!- This is a heterogeneous group of serine/threonine protein kinases
CC       that do not have an activating compound and are either non-specific
CC       or their specificity has not been analyzed to date.
CC   -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.
PR   PROSITE; PDOC00100;
DR   Q6GZV6, 019R_FRG3G ;  Q91FD5, 389L_IIV6  ;  Q54U65, 7TMK2_DICDI;
DR   Q02066, AAIP_WHEAT ;  Q2M2I8, AAK1_HUMAN ;  Q3UHJ0, AAK1_MOUSE ;
DR   P0C1X8, AAK1_RAT   ;  P45894, AAPK1_CAEEL;  Q13131, AAPK1_HUMAN;
DR   Q5EG47, AAPK1_MOUSE;  Q09136, AAPK1_PIG  ;  Q5RDH5, AAPK1_PONAB;
DR   P54645, AAPK1_RAT  ;  Q95ZQ4, AAPK2_CAEEL;  P54646, AAPK2_HUMAN;
DR   Q8BRK8, AAPK2_MOUSE;  Q28948, AAPK2_PIG  ;  Q5RD00, AAPK2_PONAB;
DR   Q09137, AAPK2_RAT  ;  Q9S7D9, ACCR1_ARATH;  O80963, ACCR2_ARATH;
DR   Q9LY50, ACCR3_ARATH;  Q9FIJ6, ACCR4_ARATH;  Q9LX29, ACR4_ARATH ;
DR   P80197, AFK_PHYPO  ;  P54741, AFSK_STRCO ;  P54742, AFSK_STRGR ;
DR   Q61XD3, AIR2_CAEBR ;  O01427, AIR2_CAEEL ;  P38080, AKL1_YEAST ;
DR   Q01314, AKT1_BOVIN ;  Q17941, AKT1_CAEEL ;  Q8INB9, AKT1_DROME ;
DR   P31749, AKT1_HUMAN ;  P31750, AKT1_MOUSE ;  P47196, AKT1_RAT   ;
DR   Q98TY9, AKT1_XENLA ;  Q7ZX15, AKT2A_XENLA;  Q6IP76, AKT2B_XENLA;
DR   Q9XTG7, AKT2_CAEEL ;  P31751, AKT2_HUMAN ;  Q60823, AKT2_MOUSE ;
DR   P47197, AKT2_RAT   ;  Q9Y243, AKT3_HUMAN ;  Q9WUA6, AKT3_MOUSE ;
DR   Q63484, AKT3_RAT   ;  P31748, AKT_MLVAT  ;  Q8RWW0, ALE2_ARATH ;
DR   P43633, ALK1_YEAST ;  P32789, ALK2_YEAST ;  Q54YF2, AMPKA_DICDI;
DR   Q8NFD2, ANKK1_HUMAN;  Q8BZ25, ANKK1_MOUSE;  Q9SR05, ANX1_ARATH ;
DR   Q3E8W4, ANX2_ARATH ;  Q06548, APK1A_ARATH;  P46573, APK1B_ARATH;
DR   O49839, APK2A_ARATH;  O49840, APK2B_ARATH;  P10398, ARAF_HUMAN ;
DR   P04627, ARAF_MOUSE ;  O19004, ARAF_PIG   ;  P14056, ARAF_RAT   ;
DR   O59790, ARK1_SCHPO ;  P53974, ARK1_YEAST ;  Q54HC6, ARKA_DICDI ;
DR   Q75CH3, ATG1_ASHGO ;  A1CHL6, ATG1_ASPCL ;  Q4WPF2, ATG1_ASPFU ;
DR   A2QIL5, ATG1_ASPNC ;  Q2UGZ7, ATG1_ASPOR ;  Q0CLX3, ATG1_ASPTN ;
DR   A6RYB8, ATG1_BOTFB ;  Q6H9I1, ATG1_BOTFU ;  Q5A649, ATG1_CANAL ;
DR   Q6FL58, ATG1_CANGA ;  Q2H6X2, ATG1_CHAGB ;  Q1DN93, ATG1_COCIM ;
DR   P87248, ATG1_COLLN ;  P0CP71, ATG1_CRYNB ;  P0CP70, ATG1_CRYNJ ;
DR   Q6BS08, ATG1_DEBHA ;  Q86CS2, ATG1_DICDI ;  Q5BCU8, ATG1_EMENI ;
DR   Q6CSX2, ATG1_KLULA ;  Q52EB3, ATG1_MAGO7 ;  A1CX69, ATG1_NEOFI ;
DR   Q7RX99, ATG1_NEUCR ;  A7KAL2, ATG1_PENCW ;  Q0UY20, ATG1_PHANO ;
DR   Q8TFN2, ATG1_PICAN ;  Q8TGI1, ATG1_PICPA ;  Q3ZDQ4, ATG1_PODAS ;
DR   Q9Y7T4, ATG1_SCHPO ;  A7F0W2, ATG1_SCLS1 ;  Q4P0K0, ATG1_USTMA ;
DR   A7TIZ4, ATG1_VANPO ;  Q6C7U0, ATG1_YARLI ;  A6ZU07, ATG1_YEAS7 ;
DR   P53104, ATG1_YEAST ;  Q9M3G7, ATM_ARATH  ;  Q751J3, ATM_ASHGO  ;
DR   Q4WVM7, ATM_ASPFU  ;  Q2U639, ATM_ASPOR  ;  Q9N3Q4, ATM_CAEEL  ;
DR   Q5ABX0, ATM_CANAL  ;  Q6FRZ9, ATM_CANGA  ;  P0CP61, ATM_CRYNB  ;
DR   P0CP60, ATM_CRYNJ  ;  Q6BV76, ATM_DEBHA  ;  Q5EAK6, ATM_DROME  ;
DR   Q5BHE2, ATM_EMENI  ;  Q4IB89, ATM_GIBZE  ;  Q13315, ATM_HUMAN  ;
DR   Q6CP76, ATM_KLULA  ;  Q62388, ATM_MOUSE  ;  Q7RZT9, ATM_NEUCR  ;
DR   Q6PQD5, ATM_PIG    ;  O74630, ATM_SCHPO  ;  Q6CAD2, ATM_YARLI  ;
DR   P38110, ATM_YEAST  ;  Q54ER4, ATR1_DICDI ;  Q9FKS4, ATR_ARATH  ;
DR   Q75DB8, ATR_ASHGO  ;  Q22258, ATR_CAEEL  ;  Q59LR2, ATR_CANAL  ;
DR   Q6FX42, ATR_CANGA  ;  Q9VXG8, ATR_DROME  ;  Q8SSE7, ATR_ENCCU  ;
DR   Q13535, ATR_HUMAN  ;  Q6CT34, ATR_KLULA  ;  Q9JKK8, ATR_MOUSE  ;
DR   A2YH41, ATR_ORYSI  ;  Q5Z987, ATR_ORYSJ  ;  Q9DE14, ATR_XENLA  ;
DR   P38111, ATR_YEAST  ;  Q6DE08, AUKBA_XENLA;  Q6GPL3, AUKBB_XENLA;
DR   Q9M077, AUR1_ARATH ;  Q683C9, AUR2_ARATH ;  O64629, AUR3_ARATH ;
DR   Q91820, AURAA_XENLA;  Q91819, AURAB_XENLA;  Q2TA06, AURKA_BOVIN;
DR   O14965, AURKA_HUMAN;  P97477, AURKA_MOUSE;  A5GFW1, AURKA_PIG  ;
DR   P59241, AURKA_RAT  ;  Q7YRC6, AURKB_BOVIN;  Q6NW76, AURKB_DANRE;
DR   Q9VKN7, AURKB_DROME;  Q96GD4, AURKB_HUMAN;  O70126, AURKB_MOUSE;
DR   Q9N0X0, AURKB_PIG  ;  O55099, AURKB_RAT  ;  A4IGM9, AURKB_XENTR;
DR   Q9UQB9, AURKC_HUMAN;  O88445, AURKC_MOUSE;  Q54WX4, AURK_DICDI ;
DR   O81906, B120_ARATH ;  Q94F62, BAK1_ARATH ;  O49545, BAME1_ARATH;
DR   Q9M2Z1, BAME2_ARATH;  O65440, BAME3_ARATH;  Q01389, BCK1_YEAST ;
DR   P11274, BCR_HUMAN  ;  Q6PAJ1, BCR_MOUSE  ;  O48814, BIK1_ARATH ;
DR   Q9NSY1, BMP2K_HUMAN;  Q91Z96, BMP2K_MOUSE;  Q04982, BRAF_CHICK ;
DR   P34908, BRAF_COTJA ;  P15056, BRAF_HUMAN ;  P28028, BRAF_MOUSE ;
DR   O22476, BRI1_ARATH ;  Q8GUQ5, BRI1_SOLLC ;  Q8L899, BRI1_SOLPE ;
DR   Q9ZWC8, BRL1_ARATH ;  Q9ZPS9, BRL2_ARATH ;  Q9LJF3, BRL3_ARATH ;
DR   Q8TDC3, BRSK1_HUMAN;  Q5RJI5, BRSK1_MOUSE;  B2DD29, BRSK1_RAT  ;
DR   Q8IWQ3, BRSK2_HUMAN;  Q69Z98, BRSK2_MOUSE;  D3ZML2, BRSK2_RAT  ;
DR   Q7WLV0, BTRW_BORBR ;  O60566, BUB1B_HUMAN;  Q9Z1S0, BUB1B_MOUSE;
DR   O43683, BUB1_HUMAN ;  O08901, BUB1_MOUSE ;  O94751, BUB1_SCHPO ;
DR   P41695, BUB1_YEAST ;  Q8SVD9, BUD12_ENCCU;  O29592, BUD32_ARCFU;
DR   Q74Z75, BUD32_ASHGO;  A1CLD2, BUD32_ASPCL;  Q4WYU4, BUD32_ASPFU;
DR   Q2U3T8, BUD32_ASPOR;  Q5AGC7, BUD32_CANAL;  Q6FTW0, BUD32_CANGA;
DR   Q2HGY8, BUD32_CHAGB;  Q1EBD3, BUD32_COCIM;  P0CP73, BUD32_CRYNB;
DR   P0CP72, BUD32_CRYNJ;  Q6BHA8, BUD32_DEBHA;  Q54W07, BUD32_DICDI;
DR   Q5BAB7, BUD32_EMENI;  B7XIB8, BUD32_ENTBH;  Q4HYC1, BUD32_GIBZE;
DR   Q6CXB9, BUD32_KLULA;  Q9P7N1, BUD32_SCHPO;  Q6C2A3, BUD32_YARLI;
DR   P53323, BUD32_YEAST;  Q754N7, CBK1_ASHGO ;  Q6FP74, CBK1_CANGA ;
DR   Q6BLJ9, CBK1_DEBHA ;  P0C1B1, CBK1_EMENI ;  P31034, CBK1_KLULA ;
DR   Q6TGC6, CBK1_PNECA ;  Q6CFS5, CBK1_YARLI ;  P53894, CBK1_YEAST ;
DR   Q9SGN7, CCR12_ARATH;  Q9SV05, CCR35_ARATH;  P27636, CDC15_YEAST;
DR   Q8SR85, CDC71_ENCCU;  Q8SR83, CDC72_ENCCU;  Q54DK3, CDC7_DICDI ;
DR   O00311, CDC7_HUMAN ;  Q9Z0H0, CDC7_MOUSE ;  P41892, CDC7_SCHPO ;
DR   P06243, CDC7_YEAST ;  Q06850, CDPK1_ARATH;  P53682, CDPK1_ORYSJ;
DR   P62344, CDPK1_PLAF7;  P62343, CDPK1_PLAFK;  Q7RAH3, CDPK1_PLAYO;
DR   Q38870, CDPK2_ARATH;  P49101, CDPK2_MAIZE;  P53683, CDPK2_ORYSJ;
DR   Q8ICR0, CDPK2_PLAF7;  O15865, CDPK2_PLAFK;  Q42479, CDPK3_ARATH;
DR   Q9NJU9, CDPK3_PLAF7;  Q7RAV5, CDPK3_PLAYO;  Q38869, CDPK4_ARATH;
DR   P62345, CDPK4_PLABA;  Q8IBS5, CDPK4_PLAF7;  Q7RJG2, CDPK4_PLAYO;
DR   A5A7I7, CDPK4_SOLTU;  Q38871, CDPK5_ARATH;  A5A7I8, CDPK5_SOLTU;
DR   Q38872, CDPK6_ARATH;  Q38873, CDPK7_ARATH;  Q42438, CDPK8_ARATH;
DR   Q38868, CDPK9_ARATH;  Q9M9V8, CDPKA_ARATH;  Q39016, CDPKB_ARATH;
DR   P53684, CDPKB_ORYSJ;  Q42396, CDPKC_ARATH;  Q8W4I7, CDPKD_ARATH;
DR   P93759, CDPKE_ARATH;  O49717, CDPKF_ARATH;  Q7XJR9, CDPKG_ARATH;
DR   Q9FMP5, CDPKH_ARATH;  Q1PE17, CDPKI_ARATH;  Q1PFH8, CDPKJ_ARATH;
DR   Q9ZV15, CDPKK_ARATH;  Q9ZSA2, CDPKL_ARATH;  Q9ZSA3, CDPKM_ARATH;
DR   Q9M101, CDPKN_ARATH;  Q9SIQ7, CDPKO_ARATH;  Q9SJ61, CDPKP_ARATH;
DR   Q9SZM3, CDPKQ_ARATH;  Q9ZSA4, CDPKR_ARATH;  Q9FKW4, CDPKS_ARATH;
DR   Q8RWL2, CDPKT_ARATH;  Q9SSF8, CDPKU_ARATH;  Q9S9V0, CDPKV_ARATH;
DR   Q6NLQ6, CDPKW_ARATH;  Q9C6P3, CDPKX_ARATH;  Q3E9C0, CDPKY_ARATH;
DR   P28582, CDPK_DAUCA ;  P28583, CDPK_SOYBN ;  P07334, CDR1_SCHPO ;
DR   P87050, CDR2_SCHPO ;  Q09170, CDS1_SCHPO ;  Q9LW83, CE101_ARATH;
DR   P38938, CEK1_SCHPO ;  Q61RA2, CHK1_CAEBR ;  Q9N3Z3, CHK1_CAEEL ;
DR   Q8AYC9, CHK1_CHICK ;  O61661, CHK1_DROME ;  Q8SSA8, CHK1_ENCCU ;
DR   O14757, CHK1_HUMAN ;  O35280, CHK1_MOUSE ;  Q91ZN7, CHK1_RAT   ;
DR   P34208, CHK1_SCHPO ;  P0C198, CHK1_USTMA ;  Q6DE87, CHK1_XENLA ;
DR   P38147, CHK1_YEAST ;  Q9U1Y5, CHK2_CAEEL ;  O96017, CHK2_HUMAN ;
DR   Q9Z265, CHK2_MOUSE ;  Q8RWC9, CIPK1_ARATH;  Q9LGV5, CIPK1_ORYSJ;
DR   Q9LYQ8, CIPK2_ARATH;  Q7X996, CIPK2_ORYSJ;  Q2V452, CIPK3_ARATH;
DR   Q8LIG4, CIPK3_ORYSJ;  Q9SUL7, CIPK4_ARATH;  Q2QMI0, CIPK4_ORYSJ;
DR   Q9LEU7, CIPK5_ARATH;  Q9LWM4, CIPK5_ORYSJ;  O65554, CIPK6_ARATH;
DR   Q6Z9F4, CIPK6_ORYSJ;  Q9XIW0, CIPK7_ARATH;  Q75GK4, CIPK7_ORYSJ;
DR   Q9STV4, CIPK8_ARATH;  Q5JLD8, CIPK8_ORYSJ;  Q9MAM1, CIPK9_ARATH;
DR   Q10SC8, CIPK9_ORYSJ;  Q9C562, CIPKA_ARATH;  Q10LQ2, CIPKA_ORYSJ;
DR   O22932, CIPKB_ARATH;  Q0JI49, CIPKB_ORYSJ;  Q9SN43, CIPKC_ARATH;
DR   Q5JLS2, CIPKC_ORYSJ;  O22971, CIPKD_ARATH;  Q5QNM6, CIPKD_ORYSJ;
DR   Q9LZW4, CIPKE_ARATH;  Q2QYM3, CIPKE_ORYSJ;  P92937, CIPKF_ARATH;
DR   Q2RBF0, CIPKF_ORYSJ;  Q9SEZ7, CIPKG_ARATH;  Q6ERS4, CIPKG_ORYSJ;
DR   Q94C40, CIPKH_ARATH;  Q75L42, CIPKH_ORYSJ;  Q9LP51, CIPKI_ARATH;
DR   Q5W736, CIPKI_ORYSJ;  Q9FJ55, CIPKJ_ARATH;  Q68Y49, CIPKJ_ORYSJ;
DR   Q9FJ54, CIPKK_ARATH;  Q60EY8, CIPKK_ORYSJ;  Q94CG0, CIPKL_ARATH;
DR   Q0D4B2, CIPKL_ORYSJ;  O80902, CIPKM_ARATH;  Q5KQF5, CIPKM_ORYSJ;
DR   Q93VD3, CIPKN_ARATH;  Q6ZLP5, CIPKN_ORYSJ;  Q9LDI3, CIPKO_ARATH;
DR   Q69Q47, CIPKO_ORYSJ;  Q8W1D5, CIPKP_ARATH;  Q5Z6X0, CIPKP_ORYSJ;
DR   Q84VQ3, CIPKQ_ARATH;  Q6H7U5, CIPKQ_ORYSJ;  Q6ERS0, CIPKR_ORYSJ;
DR   A3B529, CIPKS_ORYSJ;  Q7XIW5, CIPKT_ORYSJ;  Q5JLQ9, CIPKU_ORYSJ;
DR   Q6X4A2, CIPKV_ORYSJ;  Q2QY53, CIPKW_ORYSJ;  Q2RAX3, CIPKX_ORYSJ;
DR   P40233, CKI1_SCHPO ;  P40234, CKI2_SCHPO ;  O74135, CKI3_SCHPO ;
DR   Q9HFW2, CLA4_ASHGO ;  O14427, CLA4_CANAL ;  P48562, CLA4_YEAST ;
DR   Q54UA9, CLKA_DICDI ;  Q9SYQ8, CLV1_ARATH ;  P38679, COT1_NEUCR ;
DR   O24585, CRI4_MAIZE ;  Q9LMB9, CRK1_ARATH ;  P53681, CRK_DAUCA  ;
DR   Q08467, CSK21_ARATH;  P68399, CSK21_BOVIN;  P21868, CSK21_CHICK;
DR   P68400, CSK21_HUMAN;  Q60737, CSK21_MOUSE;  P33674, CSK21_RABIT;
DR   P19139, CSK21_RAT  ;  P28020, CSK21_XENLA;  P15790, CSK21_YEAST;
DR   Q08466, CSK22_ARATH;  P20427, CSK22_BOVIN;  P21869, CSK22_CHICK;
DR   P19784, CSK22_HUMAN;  O54833, CSK22_MOUSE;  P19454, CSK22_YEAST;
DR   O64817, CSK23_ARATH;  P18334, CSK2A_CAEEL;  Q02720, CSK2A_DICDI;
DR   P08181, CSK2A_DROME;  Q8SRU0, CSK2A_ENCCU;  P28523, CSK2A_MAIZE;
DR   Q8TG13, CSK2A_NEUCR;  P40231, CSK2A_SCHPO;  O76484, CSK2A_SPOFR;
DR   Q4U925, CSK2A_THEAN;  P28547, CSK2A_THEPA;  O14936, CSKP_HUMAN ;
DR   O70589, CSKP_MOUSE ;  Q62915, CSKP_RAT   ;  A8XJW8, CST1_CAEBR ;
DR   Q9NB31, CST1_CAEEL ;  Q05609, CTR1_ARATH ;  O14578, CTRO_HUMAN ;
DR   P49025, CTRO_MOUSE ;  P27450, CX32_ARATH ;  P53355, DAPK1_HUMAN;
DR   Q80YE7, DAPK1_MOUSE;  Q9UIK4, DAPK2_HUMAN;  Q8VDF3, DAPK2_MOUSE;
DR   O43293, DAPK3_HUMAN;  O54784, DAPK3_MOUSE;  O88764, DAPK3_RAT  ;
DR   O44997, DAPK_CAEEL ;  P32328, DBF20_YEAST;  P22204, DBF2_YEAST ;
DR   O15075, DCLK1_HUMAN;  Q9JLM8, DCLK1_MOUSE;  O08875, DCLK1_RAT  ;
DR   D2I3C6, DCLK2_AILME;  Q8N568, DCLK2_HUMAN;  Q6PGN3, DCLK2_MOUSE;
DR   Q5MPA9, DCLK2_RAT  ;  Q9C098, DCLK3_HUMAN;  Q8BWQ5, DCLK3_MOUSE;
DR   Q95QC4, DCLK_CAEEL ;  B3NKK1, DCLK_DROER ;  Q7PLI7, DCLK_DROME ;
DR   B4GXC2, DCLK_DROPE ;  B5DK35, DCLK_DROPS ;  B4IMC3, DCLK_DROSE ;
DR   B4NSS9, DCLK_DROSI ;  B4IT27, DCLK_DROYA ;  O76324, DCO_DROME  ;
DR   Q54Q69, DHKG_DICDI ;  Q09013, DMPK_HUMAN ;  P54265, DMPK_MOUSE ;
DR   Q54H46, DRKA_DICDI ;  Q54H45, DRKB_DICDI ;  Q54TA1, DRKC_DICDI ;
DR   Q54TM7, DRKD_DICDI ;  P36616, DSK1_SCHPO ;  Q86IX1, DST1_DICDI ;
DR   Q55GC2, DST2_DICDI ;  Q54EY4, DST3_DICDI ;  Q54JG7, DST4_DICDI ;
DR   P39009, DUN1_YEAST ;  Q9BQI3, E2AK1_HUMAN;  Q4R8E0, E2AK1_MACFA;
DR   Q9Z2R9, E2AK1_MOUSE;  P33279, E2AK1_RABIT;  Q63185, E2AK1_RAT  ;
DR   O13889, E2AK1_SCHPO;  P19525, E2AK2_HUMAN;  Q03963, E2AK2_MOUSE;
DR   Q63184, E2AK2_RAT  ;  Q9UTE5, E2AK2_SCHPO;  Q19192, E2AK3_CAEEL;
DR   Q9NIV1, E2AK3_DROME;  Q9NZJ5, E2AK3_HUMAN;  Q9Z2B5, E2AK3_MOUSE;
DR   Q9Z1Z1, E2AK3_RAT  ;  Q9P2K8, E2AK4_HUMAN;  Q9QZ05, E2AK4_MOUSE;
DR   C0LGT6, EFR_ARATH  ;  P32801, ELM1_YEAST ;  Q42371, ERECT_ARATH;
DR   C0LGW6, ERL1_ARATH ;  Q6XAT2, ERL2_ARATH ;  O75460, ERN1_HUMAN ;
DR   Q9EQY0, ERN1_MOUSE ;  Q76MJ5, ERN2_HUMAN ;  Q9Z2E3, ERN2_MOUSE ;
DR   Q9LYN8, EXS_ARATH  ;  C0LGF4, FEI1_ARATH ;  C0LGL9, FEI2_ARATH ;
DR   Q9SCZ4, FERON_ARATH;  Q54BF0, FHKA_DICDI ;  Q1ZXH2, FHKB_DICDI ;
DR   P34101, FHKC_DICDI ;  Q54MH0, FHKD_DICDI ;  Q54VI1, FHKE_DICDI ;
DR   O13839, FIN1_SCHPO ;  Q9NLA1, FLR4_CAEEL ;  Q9FL28, FLS2_ARATH ;
DR   P53233, FMP48_YEAST;  Q869L4, FNKA_DICDI ;  Q55FV4, FNKB_DICDI ;
DR   Q552Z2, FNKE_DICDI ;  P53739, FPK1_YEAST ;  Q54XL6, FRAY1_DICDI;
DR   Q551H4, FRAY2_DICDI;  Q03002, FRK1_YEAST ;  P23647, FUSED_DROME;
DR   A2YBX5, G11A_ORYSI ;  Q0DCT8, G11A_ORYSJ ;  Q9P7J8, GAD8_SCHPO ;
DR   O14976, GAK_HUMAN  ;  Q99KY4, GAK_MOUSE  ;  P97874, GAK_RAT    ;
DR   Q8MVR1, GBPC_DICDI ;  Q9LX30, GCN2_ARATH ;  Q9HGN1, GCN2_SCHPO ;
DR   P15442, GCN2_YEAST ;  Q55CZ1, GDT2_DICDI ;  Q55DU7, GDT4_DICDI ;
DR   Q55CY9, GDT8_DICDI ;  Q5VJL3, GDT9_DICDI ;  Q55EC7, GEFX_DICDI ;
DR   Q9W1B0, GEK_DROME  ;  Q12263, GIN4_YEAST ;  Q9URT9, GSK31_SCHPO;
DR   Q10452, GSK3_SCHPO ;  C0LGQ5, GSO1_ARATH ;  Q9FIZ3, GSO2_ARATH ;
DR   D2HXI8, GWL_AILME  ;  E1BFR5, GWL_BOVIN  ;  E2RJI4, GWL_CANFA  ;
DR   E1C2I2, GWL_CHICK  ;  Q6DBX4, GWL_DANRE  ;  Q96GX5, GWL_HUMAN  ;
DR   Q8C0P0, GWL_MOUSE  ;  Q6NTJ3, GWL_XENLA  ;  B1WAR9, GWL_XENTR  ;
DR   O14019, HAL4_SCHPO ;  P25333, HAL4_YEAST ;  Q757X8, HAL5_ASHGO ;
DR   Q6FQH2, HAL5_CANGA ;  Q6CXN5, HAL5_KLULA ;  A7TGR2, HAL5_VANPO ;
DR   A6ZQG7, HAL5_YEAS7 ;  P38970, HAL5_YEAST ;  P83103, HASP_DROME ;
DR   Q8TF76, HASP_HUMAN ;  Q9Z0R0, HASP_MOUSE ;  O13924, HASP_SCHPO ;
DR   P40235, HHP1_SCHPO ;  P40236, HHP2_SCHPO ;  P23874, HIPA_ECOLI ;
DR   Q86Z02, HIPK1_HUMAN;  O88904, HIPK1_MOUSE;  A4L9P5, HIPK1_RAT  ;
DR   Q9H2X6, HIPK2_HUMAN;  Q9WUM7, HIPK2_MESAU;  Q9QZR5, HIPK2_MOUSE;
DR   Q9H422, HIPK3_HUMAN;  Q9ERH7, HIPK3_MOUSE;  O88850, HIPK3_RAT  ;
DR   Q8NE63, HIPK4_HUMAN;  Q8WP28, HIPK4_MACFA;  Q3V016, HIPK4_MOUSE;
DR   Q4V793, HIPK4_RAT  ;  Q8T0S6, HIPPO_DROME;  Q08732, HRK1_YEAST ;
DR   P29295, HRR25_YEAST;  P50582, HSK1_SCHPO ;  Q9SGP2, HSL1_ARATH ;
DR   P34244, HSL1_YEAST ;  C0LGX3, HSL2_ARATH ;  Q2MHE4, HT1_ARATH  ;
DR   Q5XHI9, HUNKA_XENLA;  Q6VZ17, HUNKB_XENLA;  P57058, HUNK_HUMAN ;
DR   O88866, HUNK_MOUSE ;  Q68UT7, HUNK_PANTR ;  B1WAS2, HUNK_XENTR ;
DR   Q558U1, IFKA_DICDI ;  Q550L8, IFKB_DICDI ;  Q75JN1, IFKC_DICDI ;
DR   P32742, IKKE1_CAEEL;  P47042, IKS1_YEAST ;  Q54RJ4, IKSA_DICDI ;
DR   Q9LJM4, IKU2_ARATH ;  Q3SWY2, ILK_BOVIN  ;  P57044, ILK_CAVPO  ;
DR   Q13418, ILK_HUMAN  ;  O55222, ILK_MOUSE  ;  Q5R5V4, ILK_PONAB  ;
DR   Q99J82, ILK_RAT    ;  P32581, IME2_YEAST ;  C0LGP9, IMK3_ARATH ;
DR   Q755C4, IPL1_ASHGO ;  Q59S66, IPL1_CANAL ;  Q6FV07, IPL1_CANGA ;
DR   Q6BVA0, IPL1_DEBHA ;  Q8SRL5, IPL1_ENCCU ;  Q6CWQ4, IPL1_KLULA ;
DR   Q6C3J2, IPL1_YARLI ;  P38991, IPL1_YEAST ;  Q2LGB3, IRAK1_BOVIN;
DR   P51617, IRAK1_HUMAN;  Q62406, IRAK1_MOUSE;  Q9Y616, IRAK3_HUMAN;
DR   Q8K4B2, IRAK3_MOUSE;  Q1RMT8, IRAK4_BOVIN;  Q9NWZ3, IRAK4_HUMAN;
DR   Q8R4K2, IRAK4_MOUSE;  Q09499, IRE1_CAEEL ;  P32361, IRE1_YEAST ;
DR   Q55GJ2, IREA_DICDI ;  Q559A2, IRLA_DICDI ;  Q557G1, IRLB_DICDI ;
DR   Q55DJ8, IRLC_DICDI ;  Q55DJ9, IRLD_DICDI ;  Q54IE8, IRLE_DICDI ;
DR   Q556Q3, IRLF_DICDI ;  Q758T2, ISR1_ASHGO ;  Q06098, ISR1_YEAST ;
DR   Q9V3I5, JIL1_DROME ;  P36174, KAE1B_HALMA;  Q9HNL6, KAE1B_HALSA;
DR   Q18KI0, KAE1B_HALWD;  Q8TJS2, KAE1B_METAC;  Q46FS9, KAE1B_METBF;
DR   Q2FS43, KAE1B_METHJ;  Q58530, KAE1B_METJA;  A2SR70, KAE1B_METLZ;
DR   A4FZ86, KAE1B_METM5;  A9A6L6, KAE1B_METM6;  A6VJ51, KAE1B_METM7;
DR   Q8PZ92, KAE1B_METMA;  A3CXS0, KAE1B_METMJ;  Q6M056, KAE1B_METMP;
DR   A5UMH5, KAE1B_METS3;  Q2NIA4, KAE1B_METST;  O27476, KAE1B_METTH;
DR   A6US28, KAE1B_METVS;  Q3IMN2, KAE1B_NATPD;  Q6L243, KAE1B_PICTO;
DR   Q9HLA5, KAE1B_THEAC;  Q978W6, KAE1B_THEVO;  Q6L8L1, KAIC_ACAM1 ;
DR   Q8VL13, KAIC_CYAP8 ;  Q8YT40, KAIC_NOSS1 ;  Q7VAN5, KAIC_PROMA ;
DR   Q7V5W7, KAIC_PROMM ;  Q7V0C4, KAIC_PROMP ;  Q79PF4, KAIC_SYNE7 ;
DR   Q8GGL1, KAIC_SYNLI ;  Q6L8L5, KAIC_SYNP2 ;  Q7U8R3, KAIC_SYNPX ;
DR   P74646, KAIC_SYNY3 ;  Q79V60, KAIC_THEEB ;  Q6L8J9, KAIC_THEVL ;
DR   O60229, KALRN_HUMAN;  A2CG49, KALRN_MOUSE;  P97924, KALRN_RAT  ;
DR   P21901, KAPL_APLCA ;  Q8SS96, KC11_ENCCU ;  P23291, KC11_YEAST ;
DR   Q8SQR2, KC12_ENCCU ;  P23292, KC12_YEAST ;  P39962, KC13_YEAST ;
DR   Q8N752, KC1AL_HUMAN;  P67827, KC1A_BOVIN ;  P42168, KC1A_CAEEL ;
DR   P67962, KC1A_CHICK ;  P54367, KC1A_DROME ;  P48729, KC1A_HUMAN ;
DR   Q8BK63, KC1A_MOUSE ;  O19175, KC1A_PIG   ;  P67828, KC1A_RABIT ;
DR   P97633, KC1A_RAT   ;  P67829, KC1A_SHEEP ;  P67963, KC1A_XENLA ;
DR   P35507, KC1B_BOVIN ;  Q7T2E3, KC1DA_DANRE;  Q6P3K7, KC1DB_DANRE;
DR   P42158, KC1D_ARATH ;  P35508, KC1D_BOVIN ;  P48730, KC1D_HUMAN ;
DR   Q9DC28, KC1D_MOUSE ;  Q5RC72, KC1D_PONAB ;  P81123, KC1D_RABIT ;
DR   Q06486, KC1D_RAT   ;  Q5BP74, KC1D_XENLA ;  Q6P647, KC1D_XENTR ;
DR   Q5ZLL1, KC1E_CHICK ;  P49674, KC1E_HUMAN ;  Q9JMK2, KC1E_MOUSE ;
DR   A7E3X2, KC1G1_BOVIN;  Q5ZJS0, KC1G1_CHICK;  Q5PRD4, KC1G1_DANRE;
DR   Q9HCP0, KC1G1_HUMAN;  Q4R9A9, KC1G1_MACFA;  Q8BTH8, KC1G1_MOUSE;
DR   Q62761, KC1G1_RAT  ;  Q6NRT0, KC1G1_XENLA;  P78368, KC1G2_HUMAN;
DR   Q8BVP5, KC1G2_MOUSE;  Q62762, KC1G2_RAT  ;  P35509, KC1G3_BOVIN;
DR   Q9Y6M4, KC1G3_HUMAN;  Q8C4X2, KC1G3_MOUSE;  Q5R4V3, KC1G3_PONAB;
DR   Q62763, KC1G3_RAT  ;  Q556Y4, KC1_DICDI  ;  Q6QNL9, KC1_EIMTE  ;
DR   O15726, KC1_PLAF4  ;  Q8IHZ9, KC1_PLAF7  ;  Q7RBX5, KC1_PLAYO  ;
DR   Q6QNM1, KC1_TOXGO  ;  P25389, KCC4_YEAST ;  P16911, KDC1_DROME ;
DR   P16912, KDC2_DROME ;  P36005, KDX1_YEAST ;  Q9FY48, KEG_ARATH  ;
DR   P38692, KIC1_YEAST ;  Q38997, KIN10_ARATH;  P92958, KIN11_ARATH;
DR   Q8SW31, KIN1_ENCCU ;  B7XHR6, KIN1_ENTBH ;  P22987, KIN1_SCHPO ;
DR   P13185, KIN1_YEAST ;  Q20471, KIN20_CAEEL;  A8WRV1, KIN29_CAEBR;
DR   Q21017, KIN29_CAEEL;  P13186, KIN2_YEAST ;  P22209, KIN3_YEAST ;
DR   Q01919, KIN4_YEAST ;  P25341, KIN82_YEAST;  Q23915, KINX_DICDI ;
DR   Q54H05, KINY_DICDI ;  P00513, KIPA_BPT7  ;  Q9LFA2, KIPK_ARATH ;
DR   O74526, KJ45_SCHPO ;  Q6FJ85, KKQ8_CANGA ;  A6ZZF6, KKQ8_YEAS7 ;
DR   P36004, KKQ8_YEAST ;  Q12003, KP236_YEAST;  Q05652, KPEL_DROME ;
DR   P42818, KPK1_ARATH ;  P15792, KPK1_PHAVU ;  Q39030, KPK2_ARATH ;
DR   Q02595, KPK2_PLAFK ;  Q05999, KPK7_ARATH ;  P17801, KPRO_MAIZE ;
DR   Q0V7M1, KPSH1_BOVIN;  Q501V0, KPSH1_DANRE;  P11801, KPSH1_HUMAN;
DR   Q91YA2, KPSH1_MOUSE;  Q4KTY1, KPSH1_PINFU;  Q96QS6, KPSH2_HUMAN;
DR   P15443, KR14_ICHVA ;  Q00097, KR15_ICHVA ;  Q00098, KR16_ICHVA ;
DR   P32516, KR1_EHV1K  ;  P17613, KR1_SUHVK  ;  P0C6Z8, KR2_EBVA8  ;
DR   P13288, KR2_EBVB9  ;  P0C731, KR2_EBVG   ;  Q9E6Q4, KR2_GAHVM  ;
DR   Q00094, KR73_ICHVA ;  Q00095, KR74_ICHVA ;  P54644, KRAC_DICDI ;
DR   Q61UC4, KRAF1_CAEBR;  Q07292, KRAF1_CAEEL;  P11346, KRAF1_DROME;
DR   O57259, KRB2_VACCA ;  P21098, KRB2_VACCC ;  P24362, KRB2_VACCW ;
DR   Q21734, KS6A1_CAEEL;  Q15418, KS6A1_HUMAN;  P18653, KS6A1_MOUSE;
DR   Q63531, KS6A1_RAT  ;  Q18846, KS6A2_CAEEL;  Q15349, KS6A2_HUMAN;
DR   Q9WUT3, KS6A2_MOUSE;  P51812, KS6A3_HUMAN;  P18654, KS6A3_MOUSE;
DR   O75676, KS6A4_HUMAN;  Q9Z2B9, KS6A4_MOUSE;  Q5F3L1, KS6A5_CHICK;
DR   O75582, KS6A5_HUMAN;  Q8C050, KS6A5_MOUSE;  Q5R4K3, KS6A5_PONAB;
DR   Q6PFQ0, KS6A6_DANRE;  Q9UK32, KS6A6_HUMAN;  Q7TPS0, KS6A6_MOUSE;
DR   P18652, KS6AA_CHICK;  P10665, KS6AA_XENLA;  P10666, KS6AB_XENLA;
DR   Q6TJY3, KS6B1_BOVIN;  P23443, KS6B1_HUMAN;  Q8BSK8, KS6B1_MOUSE;
DR   P67998, KS6B1_RABIT;  P67999, KS6B1_RAT  ;  Q9UBS0, KS6B2_HUMAN;
DR   Q9Z1M4, KS6B2_MOUSE;  Q96S38, KS6C1_HUMAN;  Q8BLK9, KS6C1_MOUSE;
DR   Q39019, KSG10_ARATH;  P43288, KSG1_ARATH ;  Q12701, KSG1_SCHPO ;
DR   O23145, KSG2_ARATH ;  P43289, KSG3_ARATH ;  Q9FVS6, KSG4_ARATH ;
DR   Q8VZD5, KSG5_ARATH ;  Q39010, KSG6_ARATH ;  Q39011, KSG7_ARATH ;
DR   Q96287, KSG8_ARATH ;  Q39012, KSG9_ARATH ;  O04160, KSGT_BRANA ;
DR   O14328, KSP1_SCHPO ;  P38691, KSP1_YEAST ;  Q54GY6, KXCA_DICDI ;
DR   Q54C71, KXCB_DICDI ;  O95835, LATS1_HUMAN;  Q8BYR2, LATS1_MOUSE;
DR   Q9NRM7, LATS2_HUMAN;  Q7TSJ6, LATS2_MOUSE;  Q8QFP8, LIMK1_CHICK;
DR   Q8IR79, LIMK1_DROME;  P53667, LIMK1_HUMAN;  P53668, LIMK1_MOUSE;
DR   P53669, LIMK1_RAT  ;  O42565, LIMK1_XENLA;  Q32L23, LIMK2_BOVIN;
DR   P53666, LIMK2_CHICK;  P53671, LIMK2_HUMAN;  O54785, LIMK2_MOUSE;
DR   P53670, LIMK2_RAT  ;  Q54L00, LIMKA_DICDI;  P0CD62, LIMKB_DICDI;
DR   Q3E884, LK110_ARATH;  Q9FJI4, LK111_ARATH;  Q6ZMQ8, LMTK1_HUMAN;
DR   Q80YE4, LMTK1_MOUSE;  Q8IWU2, LMTK2_HUMAN;  Q3TYD6, LMTK2_MOUSE;
DR   Q96Q04, LMTK3_HUMAN;  Q5XJV6, LMTK3_MOUSE;  O61267, LOK_DROME  ;
DR   Q9M3E5, LRK11_ARATH;  Q7FK82, LRK12_ARATH;  Q9M3D8, LRK13_ARATH;
DR   Q9M3D7, LRK14_ARATH;  Q9M1G4, LRK15_ARATH;  Q9M1G3, LRK16_ARATH;
DR   Q9LSS0, LRK17_ARATH;  Q9LSR9, LRK18_ARATH;  Q9LSR8, LRK19_ARATH;
DR   Q9TZM3, LRK1_CAEEL ;  Q9FIF1, LRK21_ARATH;  Q9FIF0, LRK22_ARATH;
DR   O80939, LRK41_ARATH;  Q9M345, LRK42_ARATH;  O81292, LRK43_ARATH;
DR   O81291, LRK44_ARATH;  O04534, LRK51_ARATH;  O04533, LRK52_ARATH;
DR   O22834, LRK53_ARATH;  O22833, LRK54_ARATH;  Q96285, LRK55_ARATH;
DR   Q9LEA3, LRK56_ARATH;  Q9ZR79, LRK57_ARATH;  Q9M1Z9, LRK58_ARATH;
DR   Q9SZD5, LRK59_ARATH;  Q9SR87, LRK61_ARATH;  Q9M021, LRK62_ARATH;
DR   Q9M020, LRK63_ARATH;  Q66GN2, LRK64_ARATH;  Q9S9U1, LRK71_ARATH;
DR   O49445, LRK72_ARATH;  Q9LFH9, LRK81_ARATH;  Q9LYX1, LRK82_ARATH;
DR   Q9LXA5, LRK91_ARATH;  Q9LSL5, LRK92_ARATH;  Q9M9E0, LRKS1_ARATH;
DR   O48837, LRKS2_ARATH;  Q9STF0, LRKS3_ARATH;  Q9M2S4, LRKS4_ARATH;
DR   Q9FG33, LRKS5_ARATH;  Q9FHX3, LRKS6_ARATH;  Q9FHG4, LRKS7_ARATH;
DR   Q38SD2, LRRK1_HUMAN;  Q3UHC2, LRRK1_MOUSE;  Q5S007, LRRK2_HUMAN;
DR   Q5S006, LRRK2_MOUSE;  Q92918, M4K1_HUMAN ;  P70218, M4K1_MOUSE ;
DR   Q12851, M4K2_HUMAN ;  Q61161, M4K2_MOUSE ;  Q8IVH8, M4K3_HUMAN ;
DR   Q99JP0, M4K3_MOUSE ;  Q924I2, M4K3_RAT   ;  O95819, M4K4_HUMAN ;
DR   P97820, M4K4_MOUSE ;  Q9Y4K4, M4K5_HUMAN ;  Q8BPM2, M4K5_MOUSE ;
DR   P49136, MAPK2_CRILO;  P49071, MAPK2_DROME;  P49137, MAPK2_HUMAN;
DR   P49138, MAPK2_MOUSE;  P49139, MAPK2_RABIT;  Q3SYZ2, MAPK3_BOVIN;
DR   Q16644, MAPK3_HUMAN;  Q3UMW7, MAPK3_MOUSE;  Q66H84, MAPK3_RAT  ;
DR   Q8IW41, MAPK5_HUMAN;  O54992, MAPK5_MOUSE;  Q9P0L2, MARK1_HUMAN;
DR   Q8VHJ5, MARK1_MOUSE;  O08678, MARK1_RAT  ;  Q7KZI7, MARK2_HUMAN;
DR   Q05512, MARK2_MOUSE;  O08679, MARK2_RAT  ;  P27448, MARK3_HUMAN;
DR   Q03141, MARK3_MOUSE;  Q8VHF0, MARK3_RAT  ;  Q96L34, MARK4_HUMAN;
DR   Q8CIP4, MARK4_MOUSE;  Q9Y2H9, MAST1_HUMAN;  Q9R1L5, MAST1_MOUSE;
DR   Q810W7, MAST1_RAT  ;  Q6P0Q8, MAST2_HUMAN;  Q60592, MAST2_MOUSE;
DR   O60307, MAST3_HUMAN;  Q3U214, MAST3_MOUSE;  Q6AX33, MAST3_XENLA;
DR   O15021, MAST4_HUMAN;  Q811L6, MAST4_MOUSE;  P21965, MCK1_YEAST ;
DR   O43077, MDE3_SCHPO ;  C0LGP2, MEE39_ARATH;  Q10292, MEK1_SCHPO ;
DR   P24719, MEK1_YEAST ;  Q14680, MELK_HUMAN ;  Q61846, MELK_MOUSE ;
DR   Q23356, MIG15_CAEEL;  P30290, MIK1_SCHPO ;  P00531, MIL_AVIMH  ;
DR   Q8N4C8, MINK1_HUMAN;  Q9JM52, MINK1_MOUSE;  Q54MY9, MKCA_DICDI ;
DR   Q9NGW9, MKCB_DICDI ;  Q54JQ1, MKCC_DICDI ;  Q8SSV3, MKCD_DICDI ;
DR   Q54TN4, MKCE_DICDI ;  Q55CE0, MKCF_DICDI ;  Q58D94, MKNK1_BOVIN;
DR   Q9BUB5, MKNK1_HUMAN;  O08605, MKNK1_MOUSE;  Q4G050, MKNK1_RAT  ;
DR   Q9YGW0, MKNK1_XENLA;  Q66JF3, MKNK1_XENTR;  Q9HBH9, MKNK2_HUMAN;
DR   Q8CDB0, MKNK2_MOUSE;  Q5U2N4, MKNK2_RAT  ;  Q6P431, MKNK2_XENLA;
DR   Q66I46, MKNK2_XENTR;  P87347, MOS_APTAU  ;  Q8QHF0, MOS_ATHNI  ;
DR   Q8AX02, MOS_ATHSQ  ;  P10741, MOS_CHICK  ;  P10650, MOS_CHLAE  ;
DR   Q90XV8, MOS_CICNG  ;  Q8AX01, MOS_DENAN  ;  Q90XV6, MOS_GYMCA  ;
DR   P00540, MOS_HUMAN  ;  P00536, MOS_MOUSE  ;  P07331, MOS_MSVMH  ;
DR   P00537, MOS_MSVMM  ;  P00538, MOS_MSVMO  ;  P32593, MOS_MSVMT  ;
DR   P10421, MOS_MSVTS  ;  Q90XV9, MOS_NYCNY  ;  P50118, MOS_PIG    ;
DR   P00539, MOS_RAT    ;  Q8AX00, MOS_SIBNE  ;  Q90XV7, MOS_VULGR  ;
DR   P12965, MOS_XENLA  ;  Q54UL8, MPS1_DICDI ;  Q5VT25, MRCKA_HUMAN;
DR   Q3UU96, MRCKA_MOUSE;  O54874, MRCKA_RAT  ;  Q9Y5S2, MRCKB_HUMAN;
DR   Q7TT50, MRCKB_MOUSE;  Q7TT49, MRCKB_RAT  ;  Q6DT37, MRCKG_HUMAN;
DR   Q80UW5, MRCKG_MOUSE;  C0LGQ4, MRH1_ARATH ;  Q8SRI3, MRK1_ENCCU ;
DR   P50873, MRK1_YEAST ;  Q54DF2, MRKA_DICDI ;  Q54MV2, MRKB_DICDI ;
DR   Q54TA3, MRKC_DICDI ;  P51137, MSK1_MEDSA ;  Q40518, MSK1_TOBAC ;
DR   P51138, MSK2_MEDSA ;  P51139, MSK3_MEDSA ;  Q9P289, MST4_HUMAN ;
DR   Q99JT2, MST4_MOUSE ;  P42345, MTOR_HUMAN ;  Q9JLN9, MTOR_MOUSE ;
DR   P42346, MTOR_RAT   ;  Q86YV6, MYLK4_HUMAN;  Q5SUV5, MYLK4_MOUSE;
DR   Q8NEV4, MYO3A_HUMAN;  Q8K3H5, MYO3A_MOUSE;  Q8WXR4, MYO3B_HUMAN;
DR   Q1EG27, MYO3B_MOUSE;  O75011, NAK1_SCHPO ;  P43293, NAK_ARATH  ;
DR   Q8VYY5, NCRK_ARATH ;  Q54Y26, NDRA_DICDI ;  Q54IH8, NDRB_DICDI ;
DR   Q54P47, NDRC_DICDI ;  Q54HD2, NDRD_DICDI ;  Q6ZWH5, NEK10_HUMAN;
DR   Q3UGM2, NEK10_MOUSE;  Q8NG66, NEK11_HUMAN;  Q8WNU8, NEK11_MACFA;
DR   Q8C0Q4, NEK11_MOUSE;  Q9SLI2, NEK1_ARATH ;  Q54QD5, NEK1_DICDI ;
DR   Q96PY6, NEK1_HUMAN ;  P51954, NEK1_MOUSE ;  Q10GB1, NEK1_ORYSJ ;
DR   Q9CAU7, NEK2_ARATH ;  Q55BN8, NEK2_DICDI ;  P51955, NEK2_HUMAN ;
DR   O35942, NEK2_MOUSE ;  A2ZMH2, NEK2_ORYSI ;  Q2QMH1, NEK2_ORYSJ ;
DR   Q8RX66, NEK3_ARATH ;  Q86I06, NEK3_DICDI ;  P51956, NEK3_HUMAN ;
DR   Q9R0A5, NEK3_MOUSE ;  Q6ZEZ5, NEK3_ORYSJ ;  Q8RXT4, NEK4_ARATH ;
DR   P51957, NEK4_HUMAN ;  Q9Z1J2, NEK4_MOUSE ;  Q60DG4, NEK4_ORYSJ ;
DR   Q0WPH8, NEK5_ARATH ;  Q6P3R8, NEK5_HUMAN ;  Q7TSC3, NEK5_MOUSE ;
DR   Q94CU5, NEK5_ORYSJ ;  Q9LT35, NEK6_ARATH ;  Q9HC98, NEK6_HUMAN ;
DR   Q9ES70, NEK6_MOUSE ;  Q6YY75, NEK6_ORYSJ ;  A2BD05, NEK6_PIG   ;
DR   P59895, NEK6_RAT   ;  Q9LHI7, NEK7_ARATH ;  Q8TDX7, NEK7_HUMAN ;
DR   Q9ES74, NEK7_MOUSE ;  D3ZBE5, NEK7_RAT   ;  Q90XC2, NEK8_DANRE ;
DR   Q86SG6, NEK8_HUMAN ;  Q91ZR4, NEK8_MOUSE ;  Q8TD19, NEK9_HUMAN ;
DR   Q8K1R7, NEK9_MOUSE ;  Q7ZZC8, NEK9_XENLA ;  P84199, NEKL4_CAEEL;
DR   Q7KRY6, NHK1_DROME ;  Q9LFS4, NIK1_ARATH ;  Q8RY65, NIK2_ARATH ;
DR   Q93ZS4, NIK3_ARATH ;  Q8IY84, NIM1_HUMAN ;  Q8BHI9, NIM1_MOUSE ;
DR   P48479, NIM1_NEUCR ;  P11837, NIMA_EMENI ;  P10676, NINAC_DROME;
DR   P36003, NNK1_YEAST ;  Q8L4H4, NORK_MEDTR ;  Q8LKZ1, NORK_PEA   ;
DR   P22211, NPR1_YEAST ;  O42626, NRC2_NEUCR ;  Q08942, NRKA_TRYBB ;
DR   Q03428, NRKB_TRYBB ;  Q7Z2Y5, NRK_HUMAN  ;  Q9R0G8, NRK_MOUSE  ;
DR   O60285, NUAK1_HUMAN;  Q641K5, NUAK1_MOUSE;  Q9H093, NUAK2_HUMAN;
DR   Q8BZN4, NUAK2_MOUSE;  Q5R7G9, NUAK2_PONAB;  Q66HE5, NUAK2_RAT  ;
DR   Q5VST9, OBSCN_HUMAN;  A2AAJ9, OBSCN_MOUSE;  O59763, OCA2_SCHPO ;
DR   O13310, ORB6_SCHPO ;  Q9LSF1, OXI1_ARATH ;  O95747, OXSR1_HUMAN;
DR   Q6P9R2, OXSR1_MOUSE;  Q863I2, OXSR1_PIG  ;  Q5R495, OXSR1_PONAB;
DR   Q5JJY4, P2C04_ORYSJ;  Q940A2, P2C31_ARATH;  Q08E52, PAK1_BOVIN ;
DR   Q17850, PAK1_CAEEL ;  Q13153, PAK1_HUMAN ;  O88643, PAK1_MOUSE ;
DR   P35465, PAK1_RAT   ;  Q13177, PAK2_HUMAN ;  Q8CIN4, PAK2_MOUSE ;
DR   Q29502, PAK2_RABIT ;  Q64303, PAK2_RAT   ;  O75914, PAK3_HUMAN ;
DR   Q61036, PAK3_MOUSE ;  Q7YQL4, PAK3_PANTR ;  Q7YQL3, PAK3_PONPY ;
DR   Q62829, PAK3_RAT   ;  O96013, PAK4_HUMAN ;  Q8BTW9, PAK4_MOUSE ;
DR   Q9NQU5, PAK6_HUMAN ;  Q3ULB5, PAK6_MOUSE ;  Q5R8Z4, PAK6_PONAB ;
DR   Q9P286, PAK7_HUMAN ;  Q8C015, PAK7_MOUSE ;  Q55D99, PAKA_DICDI ;
DR   Q869N2, PAKB_DICDI ;  Q55GV3, PAKC_DICDI ;  Q55DD4, PAKD_DICDI ;
DR   Q54B33, PAKE_DICDI ;  Q869T7, PAKF_DICDI ;  Q54RV3, PAKG_DICDI ;
DR   Q556S2, PAKH_DICDI ;  Q9VXE5, PAKM_DROME ;  C0LGW2, PAM74_ARATH;
DR   A8WYE4, PAR1_CAEBR ;  Q9TW45, PAR1_CAEEL ;  A8X0C4, PAR4_CAEBR ;
DR   Q9GN62, PAR4_CAEEL ;  Q96RG2, PASK_HUMAN ;  Q8CEE6, PASK_MOUSE ;
DR   Q55E58, PATS1_DICDI;  Q9FE20, PBS1_ARATH ;  Q6NU47, PDK1A_XENLA;
DR   Q6NU98, PDK1B_XENLA;  Q32PP3, PDK1L_DANRE;  Q8N165, PDK1L_HUMAN;
DR   Q8QZR7, PDK1L_MOUSE;  Q5RER6, PDK1L_PONAB;  Q9XF67, PDPK1_ARATH;
DR   Q9Y1J3, PDPK1_CAEEL;  Q9W0V1, PDPK1_DROME;  O15530, PDPK1_HUMAN;
DR   Q9Z2A0, PDPK1_MOUSE;  O55173, PDPK1_RAT  ;  Q4V3C8, PDPK2_ARATH;
DR   Q6A1A2, PDPK2_HUMAN;  Q54TW2, PDPKA_DICDI;  Q54PK9, PDPKB_DICDI;
DR   Q9C660, PEK10_ARATH;  Q9SGY7, PEK11_ARATH;  Q9ZUE0, PEK12_ARATH;
DR   Q9CAL8, PEK13_ARATH;  O65530, PEK14_ARATH;  Q9C821, PEK15_ARATH;
DR   Q9SSL9, PEPR1_ARATH;  Q9FZ59, PEPR2_ARATH;  Q9LV48, PERK1_ARATH;
DR   Q9LK03, PERK2_ARATH;  Q1PEM5, PERK3_ARATH;  Q9ZNQ8, PERK4_ARATH;
DR   Q8GX23, PERK5_ARATH;  Q9LS95, PERK6_ARATH;  Q9XI96, PERK7_ARATH;
DR   Q9FFW5, PERK8_ARATH;  Q9SX31, PERK9_ARATH;  Q54QQ1, PHG2_DICDI ;
DR   O48963, PHOT1_ARATH;  P93025, PHOT2_ARATH;  Q9ST27, PHOT2_ORYSJ;
DR   Q2QYY8, PHT1A_ORYSJ;  Q2RBR1, PHT1B_ORYSJ;  P25848, PHY1_CERPU ;
DR   Q99570, PI3R4_HUMAN;  Q8VD65, PI3R4_MOUSE;  Q5R9I3, PI3R4_PONAB;
DR   P0C0R5, PI3R4_RAT  ;  Q64FQ2, PID2_ARATH ;  Q94E49, PID2_ORYSJ ;
DR   O64682, PID_ARATH  ;  Q2QM77, PID_ORYSJ  ;  Q9N0P9, PIM1_BOVIN ;
DR   Q95LJ0, PIM1_FELCA ;  P11309, PIM1_HUMAN ;  P06803, PIM1_MOUSE ;
DR   P26794, PIM1_RAT   ;  Q9YHZ5, PIM2_DANRE ;  Q9P1W9, PIM2_HUMAN ;
DR   Q62070, PIM2_MOUSE ;  Q9PU85, PIM3_COTJA ;  Q86V86, PIM3_HUMAN ;
DR   P58750, PIM3_MOUSE ;  O70444, PIM3_RAT   ;  Q91822, PIM3_XENLA ;
DR   Q09298, PINK1_CAEEL;  Q9BXM7, PINK1_HUMAN;  Q99MQ3, PINK1_MOUSE;
DR   O14132, PIT1_SCHPO ;  P85193, PK01_HELAN ;  P42493, PK1_ASFB7  ;
DR   P0C8F4, PK1_ASFK5  ;  P34206, PK1_ASFM2  ;  P0C8F2, PK1_ASFP4  ;
DR   P0C8F3, PK1_ASFWA  ;  P41415, PK1_NPVAC  ;  P41719, PK1_NPVHZ  ;
DR   P41720, PK1_NPVLD  ;  O10269, PK1_NPVOP  ;  Q9KIG4, PK1_STRTO  ;
DR   P28178, PK2_DICDI  ;  P41676, PK2_NPVAC  ;  P32871, PK3CA_BOVIN;
DR   P42336, PK3CA_HUMAN;  P42337, PK3CA_MOUSE;  P34102, PK3_DICDI  ;
DR   P34103, PK4_DICDI  ;  P54739, PKAA_STRCO ;  P54740, PKAB_STRCO ;
DR   P34100, PKD1_DICDI ;  Q552E9, PKGA_DICDI ;  Q03407, PKH1_YEAST ;
DR   Q12236, PKH2_YEAST ;  Q753D9, PKH3_ASHGO ;  Q03306, PKH3_YEAST ;
DR   P37562, PKN1_BACSU ;  Q822R1, PKN1_CHLCV ;  Q9PKP3, PKN1_CHLMU ;
DR   Q7AJA5, PKN1_CHLPN ;  O84147, PKN1_CHLTR ;  Q8FUI5, PKN1_COREF ;
DR   Q8NU98, PKN1_CORGL ;  P33973, PKN1_MYXXA ;  Q8R9T6, PKN1_THETN ;
DR   Q97IC2, PKN2_CLOAB ;  Q8XJL8, PKN2_CLOPE ;  Q8FUI4, PKN2_COREF ;
DR   Q8NU97, PKN2_CORGL ;  P54736, PKN2_MYXXA ;  Q9XBQ0, PKN3_MYXXA ;
DR   P54737, PKN5_MYXXA ;  P54738, PKN6_MYXXA ;  Q8G4G1, PKNA2_BIFLO;
DR   P65727, PKNA_MYCBO ;  P54743, PKNA_MYCLE ;  P65726, PKNA_MYCTU ;
DR   P54734, PKNA_NOSS1 ;  Q8G6P9, PKNB_BIFLO ;  Q9CEF5, PKNB_LACLA ;
DR   P0A5S5, PKNB_MYCBO ;  P54744, PKNB_MYCLE ;  P0A5S4, PKNB_MYCTU ;
DR   Q5L5J7, PKND_CHLAB ;  Q822K5, PKND_CHLCV ;  Q255D2, PKND_CHLFF ;
DR   Q9PK92, PKND_CHLMU ;  Q9Z986, PKND_CHLPN ;  B0B7L7, PKND_CHLT2 ;
DR   Q3KM61, PKND_CHLTA ;  B0BBT2, PKND_CHLTB ;  O84303, PKND_CHLTR ;
DR   O05871, PKND_MYCTU ;  Q6MAN0, PKND_PARUW ;  Q7TZN3, PKNE_MYCBO ;
DR   P72001, PKNE_MYCTU ;  Q7TZN1, PKNF_MYCBO ;  P72003, PKNF_MYCTU ;
DR   P65729, PKNG_MYCBO ;  P57993, PKNG_MYCLE ;  P65728, PKNG_MYCTU ;
DR   Q7U095, PKNH_MYCBO ;  Q11053, PKNH_MYCTU ;  P65731, PKNI_MYCBO ;
DR   P65730, PKNI_MYCTU ;  P65733, PKNJ_MYCBO ;  P65732, PKNJ_MYCTU ;
DR   Q7TXA9, PKNK_MYCBO ;  P95078, PKNK_MYCTU ;  Q7TYY6, PKNL_MYCBO ;
DR   O53510, PKNL_MYCTU ;  P47355, PKNS_MYCGE ;  P75524, PKNS_MYCPN ;
DR   Q9XA16, PKNX_STRCO ;  Q01577, PKPA_PHYBL ;  Q9S2C0, PKSC_STRCO ;
DR   P49695, PKWA_THECU ;  Q8GVC7, PKZ1_PHYIN ;  D0N4E2, PKZ1_PHYIT ;
DR   Q86HN7, PLK_DICDI  ;  Q20085, PMY11_CAEEL;  Q626B1, PMY13_CAEBR;
DR   O18209, PMY13_CAEEL;  Q9NI63, PMYT1_DROME;  Q99640, PMYT1_HUMAN;
DR   Q9ESG9, PMYT1_MOUSE;  Q91618, PMYT1_XENLA;  Q9SPK4, PPCK1_ARATH;
DR   Q93VK0, PPCK2_ARATH;  O14047, PPK11_SCHPO;  Q10078, PPK13_SCHPO;
DR   Q09831, PPK14_SCHPO;  Q9P6P3, PPK15_SCHPO;  Q9URY1, PPK16_SCHPO;
DR   Q8TFG6, PPK18_SCHPO;  O42900, PPK19_SCHPO;  Q9HFF4, PPK1_SCHPO ;
DR   Q9Y7J6, PPK21_SCHPO;  Q9USX7, PPK22_SCHPO;  O60145, PPK23_SCHPO;
DR   O94647, PPK24_SCHPO;  O59697, PPK25_SCHPO;  O74815, PPK27_SCHPO;
DR   Q9USS2, PPK29_SCHPO;  O43066, PPK30_SCHPO;  O94324, PPK31_SCHPO;
DR   O74426, PPK33_SCHPO;  Q9UU87, PPK34_SCHPO;  O94487, PPK35_SCHPO;
DR   O94537, PPK4_SCHPO ;  Q09815, PPK5_SCHPO ;  Q9UTH3, PPK6_SCHPO ;
DR   Q09792, PPK8_SCHPO ;  P40494, PRK1_YEAST ;  Q81WH6, PRKC_BACAN ;
DR   O34507, PRKC_BACSU ;  A6QGC0, PRKC_STAAE ;  Q8WN22, PRKDC_CANFA;
DR   Q8QGX4, PRKDC_CHICK;  Q54UC0, PRKDC_DICDI;  P78527, PRKDC_HUMAN;
DR   P97313, PRKDC_MOUSE;  Q9DEI1, PRKDC_XENLA;  P51817, PRKX_HUMAN ;
DR   Q922R0, PRKX_MOUSE ;  O43930, PRKY_HUMAN ;  Q08DZ2, PRP4B_BOVIN;
DR   Q54WE5, PRP4B_DICDI;  Q13523, PRP4B_HUMAN;  Q61136, PRP4B_MOUSE;
DR   Q5R814, PRP4B_PONAB;  Q5RKH1, PRP4B_RAT  ;  Q07538, PRP4_SCHPO ;
DR   Q96S44, PRPK_HUMAN ;  Q99PW4, PRPK_MOUSE ;  P28708, PRR1_YEAST ;
DR   Q12310, PRR2_YEAST ;  P31374, PSK1_YEAST ;  Q08217, PSK2_YEAST ;
DR   Q9ZVR7, PSKR1_ARATH;  Q8LPB4, PSKR1_DAUCA;  Q9FN37, PSKR2_ARATH;
DR   Q9C7S5, PSYR1_ARATH;  Q41328, PTI1_SOLLC ;  P36002, PTK1_YEAST ;
DR   Q6FRE7, PTK2_CANGA ;  P47116, PTK2_YEAST ;  Q1ZXC8, PXI_DICDI  ;
DR   Q9FRS6, PXL1_ARATH ;  Q9M0G7, PXL2_ARATH ;  Q8SSS9, QKGA_DICDI ;
DR   Q02099, RAD3_SCHPO ;  P22216, RAD53_YEAST;  A7E3S4, RAF1_BOVIN ;
DR   P05625, RAF1_CHICK ;  P04049, RAF1_HUMAN ;  Q99N57, RAF1_MOUSE ;
DR   Q5R5M7, RAF1_PONAB ;  P11345, RAF1_RAT   ;  P09560, RAF1_XENLA ;
DR   P00532, RAF_MSV36  ;  P40230, RAG8_KLULA ;  P08092, RAN1_SCHPO ;
DR   Q8H1D6, RBK1_ARATH ;  Q8RXC8, RBK2_ARATH ;  C0LGV1, RCH1_ARATH ;
DR   Q9LHP4, RCH2_ARATH ;  P38622, RCK1_YEAST ;  P38623, RCK2_YEAST ;
DR   Q54XQ2, RCKA_DICDI ;  P38615, RIM11_YEAST;  P43565, RIM15_YEAST;
DR   O28471, RIO1_ARCFU ;  Q54VD8, RIO1_DICDI ;  Q8SVI7, RIO1_ENCCU ;
DR   Q57886, RIO1_METJA ;  O42650, RIO1_SCHPO ;  Q03021, RIO1_THEAC ;
DR   Q12196, RIO1_YEAST ;  O30245, RIO2_ARCFU ;  Q54T05, RIO2_DICDI ;
DR   Q58473, RIO2_METJA ;  Q9P7W5, RIO2_SCHPO ;  P40160, RIO2_YEAST ;
DR   Q9BRS2, RIOK1_HUMAN;  Q922Q2, RIOK1_MOUSE;  Q9BVS4, RIOK2_HUMAN;
DR   Q9CQS5, RIOK2_MOUSE;  Q1RMT7, RIOK3_BOVIN;  O14730, RIOK3_HUMAN;
DR   Q9DBU3, RIOK3_MOUSE;  Q13546, RIPK1_HUMAN;  Q60855, RIPK1_MOUSE;
DR   Q3SZJ2, RIPK2_BOVIN;  O43353, RIPK2_HUMAN;  P58801, RIPK2_MOUSE;
DR   Q9Y572, RIPK3_HUMAN;  Q9QZL0, RIPK3_MOUSE;  Q9Z2P5, RIPK3_RAT  ;
DR   P57078, RIPK4_HUMAN;  Q9ERK0, RIPK4_MOUSE;  Q9FXF2, RKF1_ARATH ;
DR   P93050, RKF3_ARATH ;  Q02723, RKIN1_SECCE;  Q9ZT07, RKS1_ARATH ;
DR   Q9LQQ8, RLCK7_ARATH;  Q39202, RLK1_ARATH ;  P47735, RLK5_ARATH ;
DR   Q9LIG2, RLK6_ARATH ;  Q9FN94, RLK7_ARATH ;  C0LGU0, RLK_ARATH  ;
DR   P27966, RMIL_AVEVR ;  P10533, RMIL_AVII1 ;  Q6XHA5, ROC11_DICDI;
DR   Q8MIT6, ROCK1_BOVIN;  Q13464, ROCK1_HUMAN;  P70335, ROCK1_MOUSE;
DR   P61584, ROCK1_PANTR;  O77819, ROCK1_RABIT;  Q63644, ROCK1_RAT  ;
DR   Q28021, ROCK2_BOVIN;  O75116, ROCK2_HUMAN;  P70336, ROCK2_MOUSE;
DR   Q62868, ROCK2_RAT  ;  A8WVU9, ROCK_CAEBR ;  P92199, ROCK_CAEEL ;
DR   Q6XHB2, ROCO4_DICDI;  Q1ZXD6, ROCO5_DICDI;  Q54WS5, ROCO6_DICDI;
DR   Q55GE6, ROCO7_DICDI;  Q54M77, ROCO8_DICDI;  Q6XHA7, ROCO9_DICDI;
DR   Q9ZRF9, RPK1_ARATH ;  P93194, RPK1_IPONI ;  Q9S7I6, RPK2_ARATH ;
DR   Q9Y6S9, RPKL1_HUMAN;  Q8R2S1, RPKL1_MOUSE;  Q5RA67, RPKL1_PONAB;
DR   P42411, RSBT_BACSU ;  A7Z1M9, RSBW_BACA2 ;  C3P2P9, RSBW_BACAA ;
DR   C3LD19, RSBW_BACAC ;  A0RAL4, RSBW_BACAH ;  Q9K5J7, RSBW_BACAN ;
DR   B7JCS0, RSBW_BACC0 ;  Q73CI0, RSBW_BACC1 ;  B7IK73, RSBW_BACC2 ;
DR   C1EZZ5, RSBW_BACC3 ;  B7HFX0, RSBW_BACC4 ;  B7HYQ6, RSBW_BACC7 ;
DR   B9ISD5, RSBW_BACCQ ;  Q81H23, RSBW_BACCR ;  Q63F14, RSBW_BACCZ ;
DR   Q9KFF1, RSBW_BACHD ;  Q6HMH0, RSBW_BACHK ;  Q65N49, RSBW_BACLD ;
DR   O50231, RSBW_BACLI ;  A8FA73, RSBW_BACP2 ;  P17904, RSBW_BACSU ;
DR   A9VHG0, RSBW_BACWK ;  Q92DC2, RSBW_LISIN ;  C1L1G4, RSBW_LISMC ;
DR   Q721S2, RSBW_LISMF ;  B8DG65, RSBW_LISMH ;  Q8Y8K6, RSBW_LISMO ;
DR   A0AH12, RSBW_LISW6 ;  Q8CXL7, RSBW_OCEIH ;  A7X4P1, RSBW_STAA1 ;
DR   A6U3F0, RSBW_STAA2 ;  Q2FF59, RSBW_STAA3 ;  Q2FWJ3, RSBW_STAA8 ;
DR   A5IUL1, RSBW_STAA9 ;  Q2YUI8, RSBW_STAAB ;  Q5HED6, RSBW_STAAC ;
DR   A6QIR1, RSBW_STAAE ;  P0A0H6, RSBW_STAAM ;  P0A0H7, RSBW_STAAN ;
DR   Q6GF08, RSBW_STAAR ;  Q6G7P4, RSBW_STAAS ;  A8Z4W8, RSBW_STAAT ;
DR   P0C1V2, RSBW_STAAU ;  Q8NVI5, RSBW_STAAW ;  P0C0M6, RSBW_STAEP ;
DR   Q5HMF0, RSBW_STAEQ ;  P0C0M7, RSBW_STAES ;  Q12100, RTK1_YEAST ;
DR   Q19469, SAD1_CAEEL ;  P38990, SAK1_YEAST ;  Q55CW3, SAMKA_DICDI;
DR   Q54P26, SAMKB_DICDI;  Q55CW2, SAMKC_DICDI;  Q75LR7, SAPK1_ORYSJ;
DR   A2YNT8, SAPK2_ORYSI;  Q0D4J7, SAPK2_ORYSJ;  A2ZAB5, SAPK3_ORYSI;
DR   P0C5D6, SAPK3_ORYSJ;  Q5N942, SAPK4_ORYSJ;  Q7XKA8, SAPK5_ORYSJ;
DR   Q6ZI44, SAPK6_ORYSJ;  Q7XQP4, SAPK7_ORYSJ;  Q7Y0B9, SAPK8_ORYSJ;
DR   Q75V57, SAPK9_ORYSJ;  Q75H77, SAPKA_ORYSJ;  A8XJL7, SAX1_CAEBR ;
DR   Q2L6W9, SAX1_CAEEL ;  Q9SKB2, SBIR1_ARATH;  Q90ZY4, SBK1_DANRE ;
DR   Q52WX2, SBK1_HUMAN ;  Q8QZX0, SBK1_MOUSE ;  Q9Z335, SBK1_RAT   ;
DR   P0C263, SBK2_HUMAN ;  P0C5K1, SBK2_MOUSE ;  B1WBU5, SBK2_RAT   ;
DR   P11792, SCH9_YEAST ;  P50530, SCK1_SCHPO ;  Q10364, SCK2_SCHPO ;
DR   Q9LPZ9, SD113_ARATH;  O81833, SD11_ARATH ;  O64782, SD129_ARATH;
DR   Q9S972, SD16_ARATH ;  Q39086, SD17_ARATH ;  O81905, SD18_ARATH ;
DR   Q39203, SD22_ARATH ;  Q8RWZ5, SD25_ARATH ;  P93756, SD31_ARATH ;
DR   Q8T2I8, SEPA_DICDI ;  A2QHV0, SEPH_ASPNC ;  Q0CL79, SEPH_ASPTN ;
DR   Q5B4Z3, SEPH_EMENI ;  Q94AG2, SERK1_ARATH;  Q9XIC7, SERK2_ARATH;
DR   Q9SKG5, SERK4_ARATH;  Q8LPS5, SERK5_ARATH;  P0C264, SG110_HUMAN;
DR   P0C5K0, SG110_MOUSE;  Q96LW2, SG494_HUMAN;  Q5SYL1, SG494_MOUSE;
DR   P18431, SGG_DROME  ;  Q6GPN6, SGK1A_XENLA;  Q6GLY8, SGK1B_XENLA;
DR   A7MB74, SGK1_BOVIN ;  A8XNJ6, SGK1_CAEBR ;  Q2PJ68, SGK1_CAEEL ;
DR   Q6U1I9, SGK1_CHICK ;  Q7ZTW4, SGK1_DANRE ;  Q5Q0U5, SGK1_FUNHE ;
DR   O00141, SGK1_HUMAN ;  Q4R633, SGK1_MACFA ;  Q9WVC6, SGK1_MOUSE ;
DR   Q9XT18, SGK1_RABIT ;  Q06226, SGK1_RAT   ;  Q5BKK4, SGK1_XENTR ;
DR   Q9HBY8, SGK2_HUMAN ;  Q9QZS5, SGK2_MOUSE ;  Q8R4U9, SGK2_RAT   ;
DR   Q96BR1, SGK3_HUMAN ;  Q9ERE3, SGK3_MOUSE ;  Q5R7A7, SGK3_PONAB ;
DR   Q8R4V0, SGK3_RAT   ;  Q10056, SHK2_SCHPO ;  Q54RB7, SHKA_DICDI ;
DR   Q54IP4, SHKB_DICDI ;  Q54Y55, SHKC_DICDI ;  Q54U31, SHKD_DICDI ;
DR   Q54G43, SHKE_DICDI ;  O14305, SID1_SCHPO ;  Q09898, SID2_SCHPO ;
DR   P57059, SIK1_HUMAN ;  Q60670, SIK1_MOUSE ;  Q9R1U5, SIK1_RAT   ;
DR   Q9IA88, SIK2_CHICK ;  Q9H0K1, SIK2_HUMAN ;  Q8CFH6, SIK2_MOUSE ;
DR   Q5REX1, SIK2_PONAB ;  Q6NSM8, SIK3_DANRE ;  Q9Y2K2, SIK3_HUMAN ;
DR   Q6P4S6, SIK3_MOUSE ;  Q12469, SKM1_YEAST ;  Q12505, SKS1_YEAST ;
DR   Q86A12, SKY1_DICDI ;  Q03656, SKY1_YEAST ;  O55092, SLK_CAVPO  ;
DR   Q9H2G2, SLK_HUMAN  ;  O54988, SLK_MOUSE  ;  O08815, SLK_RAT    ;
DR   Q61CW2, SMG1_CAEBR ;  O01510, SMG1_CAEEL ;  Q553E9, SMG1_DICDI ;
DR   Q70PP2, SMG1_DROME ;  Q96Q15, SMG1_HUMAN ;  Q8BKX6, SMG1_MOUSE ;
DR   Q9QYZ6, SMK2A_MOUSE;  Q9QYZ3, SMK2B_MOUSE;  Q9QYZ5, SMK3_MOUSE ;
DR   A0JLX3, SMK4A_MOUSE;  A2KF29, SMKTR_MOUSE;  Q8C0V7, SMKW_MOUSE ;
DR   Q8C0X8, SMKX_MOUSE ;  A0AUV4, SMKY_MOUSE ;  Q8C0N0, SMKZ_MOUSE ;
DR   A1A5Q6, SMK_RAT    ;  Q9QYZ4, SMOK1_MOUSE;  P52497, SNF1_CANAL ;
DR   Q00372, SNF1_CANGA ;  O94168, SNF1_CANTR ;  O74536, SNF1_SCHPO ;
DR   P06782, SNF1_YEAST ;  Q9NRH2, SNRK_HUMAN ;  Q8VDU5, SNRK_MOUSE ;
DR   Q63553, SNRK_RAT   ;  B7GKG6, SP2AB_ANOFW;  A7Z692, SP2AB_BACA2;
DR   C3P7L0, SP2AB_BACAA;  C3LIU0, SP2AB_BACAC;  A0RI78, SP2AB_BACAH;
DR   Q81MF4, SP2AB_BACAN;  B7JLS6, SP2AB_BACC0;  Q731M3, SP2AB_BACC1;
DR   B7IWI6, SP2AB_BACC2;  C1EQU8, SP2AB_BACC3;  B7H965, SP2AB_BACC4;
DR   B7HN53, SP2AB_BACC7;  A7GS97, SP2AB_BACCN;  P70878, SP2AB_BACCO;
DR   B9IWT7, SP2AB_BACCQ;  Q819B3, SP2AB_BACCR;  Q635K7, SP2AB_BACCZ;
DR   Q9KCN2, SP2AB_BACHD;  Q6HE93, SP2AB_BACHK;  Q65HU3, SP2AB_BACLD;
DR   P26778, SP2AB_BACLI;  P35148, SP2AB_BACME;  A8FET0, SP2AB_BACP2;
DR   Q5WH26, SP2AB_BACSK;  P10728, SP2AB_BACSU;  A9VFH8, SP2AB_BACWK;
DR   Q97GQ9, SP2AB_CLOAB;  A6LRL7, SP2AB_CLOB8;  B2V2G9, SP2AB_CLOBA;
DR   B2TLY1, SP2AB_CLOBB;  B9E5R9, SP2AB_CLOK1;  A5N217, SP2AB_CLOK5;
DR   A0PZS6, SP2AB_CLONN;  Q0TNR1, SP2AB_CLOP1;  Q8XIR5, SP2AB_CLOPE;
DR   Q0SRC7, SP2AB_CLOPS;  P59623, SP2AB_CLOTE;  Q5KXJ2, SP2AB_GEOKA;
DR   O32727, SP2AB_GEOSE;  C5D403, SP2AB_GEOSW;  A4IQI5, SP2AB_GEOTN;
DR   O32724, SP2AB_LYSSH;  Q8EQ73, SP2AB_OCEIH;  O32721, SP2AB_PAEPO;
DR   P59624, SP2AB_PASPE;  B0K9G3, SP2AB_THEP3;  B0K150, SP2AB_THEPX;
DR   Q8RAA8, SP2AB_THETN;  Q696W0, SPEG_DANRE ;  Q15772, SPEG_HUMAN ;
DR   Q62407, SPEG_MOUSE ;  Q63638, SPEG_RAT   ;  Q61IS6, SPK1_CAEBR ;
DR   Q03563, SPK1_CAEEL ;  Q86AT8, SPKA_DICDI ;  Q9FAB3, SPKA_SYNY3 ;
DR   P74297, SPKB_SYNY3 ;  P74745, SPKC_SYNY3 ;  P54735, SPKD_SYNY3 ;
DR   P73469, SPKF_SYNY3 ;  Q8SSY6, SPKUL_DICDI;  Q9UQY9, SPO4_SCHPO ;
DR   P08458, SPS1_YEAST ;  O94547, SRK1_SCHPO ;  P43291, SRK2A_ARATH;
DR   Q9C958, SRK2B_ARATH;  Q9M9E9, SRK2C_ARATH;  Q39192, SRK2D_ARATH;
DR   Q940H6, SRK2E_ARATH;  Q9SMQ4, SRK2F_ARATH;  P43292, SRK2G_ARATH;
DR   Q9FFP9, SRK2H_ARATH;  Q39193, SRK2I_ARATH;  O64812, SRK2J_ARATH;
DR   Q09092, SRK6_BRAOE ;  B0F2A9, SRK_ARATH  ;  Q96SB4, SRPK1_HUMAN;
DR   O70551, SRPK1_MOUSE;  Q5RD27, SRPK1_PONAB;  P78362, SRPK2_HUMAN;
DR   O54781, SRPK2_MOUSE;  Q9UPE1, SRPK3_HUMAN;  Q9Z0G2, SRPK3_MOUSE;
DR   B8Y466, SRPK3_PIG  ;  Q45FA5, SRPK_PHYPO ;  P25390, SSK22_YEAST;
DR   P50526, SSP1_SCHPO ;  Q9UEE5, ST17A_HUMAN;  Q9GM70, ST17A_RABIT;
DR   O94768, ST17B_HUMAN;  Q8BG48, ST17B_MOUSE;  Q91XS8, ST17B_RAT  ;
DR   Q8WU08, ST32A_HUMAN;  Q8BGW6, ST32A_MOUSE;  Q9NY57, ST32B_HUMAN;
DR   Q9JJX8, ST32B_MOUSE;  Q86UX6, ST32C_HUMAN;  Q8QZV4, ST32C_MOUSE;
DR   Q9Y2H1, ST38L_HUMAN;  Q7TSE6, ST38L_MOUSE;  B5VNQ3, STE11_YEAS6;
DR   A7A1P0, STE11_YEAS7;  P23561, STE11_YEAST;  Q75DK7, STE20_ASHGO;
DR   Q4WHP3, STE20_ASPFU;  Q2ULU3, STE20_ASPOR;  Q92212, STE20_CANAL;
DR   Q6FN53, STE20_CANGA;  Q6BNF3, STE20_DEBHA;  Q5BBL3, STE20_EMENI;
DR   Q6CVA2, STE20_KLULA;  Q7Z8E9, STE20_MAGO7;  Q7RZD3, STE20_NEUCR;
DR   Q2VWQ3, STE20_PENMA;  P50527, STE20_SCHPO;  Q4P5N0, STE20_USTMA;
DR   Q6C3D7, STE20_YARLI;  Q03497, STE20_YEAST;  O94804, STK10_HUMAN;
DR   O55098, STK10_MOUSE;  Q0GGW5, STK11_CHICK;  Q54WJ0, STK11_DICDI;
DR   Q15831, STK11_HUMAN;  Q9WTK7, STK11_MOUSE;  D4AE59, STK11_RAT  ;
DR   Q91604, STK11_XENLA;  O75716, STK16_HUMAN;  O88697, STK16_MOUSE;
DR   P57760, STK16_RAT  ;  Q54WC0, STK19_DICDI;  P49842, STK19_HUMAN;
DR   Q9JHN8, STK19_MOUSE;  Q9Y6E0, STK24_HUMAN;  Q99KH8, STK24_MOUSE;
DR   Q3SWY6, STK25_BOVIN;  O00506, STK25_HUMAN;  Q9Z2W1, STK25_MOUSE;
DR   Q9BXU1, STK31_HUMAN;  Q99MW1, STK31_MOUSE;  Q0VD22, STK33_BOVIN;
DR   Q9BYT3, STK33_HUMAN;  Q924X7, STK33_MOUSE;  Q8TDR2, STK35_HUMAN;
DR   Q80ZW0, STK35_MOUSE;  Q9NRP7, STK36_HUMAN;  Q69ZM6, STK36_MOUSE;
DR   Q5RAJ5, STK36_PONAB;  A2VDV2, STK38_BOVIN;  Q15208, STK38_HUMAN;
DR   Q91VJ4, STK38_MOUSE;  Q5R8M1, STK38_PONAB;  Q9UEW8, STK39_HUMAN;
DR   Q9Z1W9, STK39_MOUSE;  O88506, STK39_RAT  ;  Q7ZUQ3, STK3_DANRE ;
DR   Q13188, STK3_HUMAN ;  Q9JI10, STK3_MOUSE ;  O54748, STK3_RAT   ;
DR   Q6IP06, STK3_XENLA ;  Q17QV9, STK40_BOVIN;  Q7T0B1, STK40_CHICK;
DR   Q8N2I9, STK40_HUMAN;  Q7TNL3, STK40_MOUSE;  Q5R667, STK40_PONAB;
DR   Q7TNL4, STK40_RAT  ;  Q7T0B0, STK40_XENLA;  Q55FS2, STK4L_DICDI;
DR   A4K2W5, STK4_AOTNA ;  Q5E9L6, STK4_BOVIN ;  Q5ZJK4, STK4_CHICK ;
DR   A4K2Y1, STK4_CHLAE ;  A4K2P5, STK4_COLGU ;  O61125, STK4_DICDI ;
DR   Q13043, STK4_HUMAN ;  A4K2S1, STK4_LEMCA ;  A4K2T0, STK4_MACMU ;
DR   Q9JI11, STK4_MOUSE ;  A4K2Q5, STK4_OTOGA ;  A4K2M3, STK4_PAPAN ;
DR   Q802A6, STK4_SQUAC ;  Q6PA14, STK4_XENLA ;  Q6P3Q4, STK4_XENTR ;
DR   P83098, STLK_DROME ;  Q9LZV4, STN8_ARATH ;  Q9FMY3, STPKL_ARATH;
DR   Q9S713, STT7_ARATH ;  Q84V18, STT7_CHLRE ;  P46549, SULU_CAEEL ;
DR   O61122, SVKA_DICDI ;  P32944, SWE1_YEAST ;  P51123, TAF1_DROME ;
DR   P21675, TAF1_HUMAN ;  Q60544, TAF1_MESAU ;  Q80UV9, TAF1_MOUSE ;
DR   Q6NU21, TAO1A_XENLA;  Q7ZYJ0, TAO1B_XENLA;  Q7L7X3, TAOK1_HUMAN;
DR   Q5F2E8, TAOK1_MOUSE;  O88664, TAOK1_RAT  ;  Q9UL54, TAOK2_HUMAN;
DR   Q6ZQ29, TAOK2_MOUSE;  Q9JLS3, TAOK2_RAT  ;  Q6GPK9, TAOK2_XENLA;
DR   Q9I9E0, TAOK3_CHICK;  Q9H2K8, TAOK3_HUMAN;  Q8BYC6, TAOK3_MOUSE;
DR   Q5R4F3, TAOK3_PONAB;  Q53UA7, TAOK3_RAT  ;  Q6DD27, TAOK3_XENLA;
DR   Q9UHD2, TBK1_HUMAN ;  Q9WUN2, TBK1_MOUSE ;  Q6DFJ6, TBK1_XENLA ;
DR   Q03533, TDA1_YEAST ;  Q9FII5, TDR_ARATH  ;  Q8WZ42, TITIN_HUMAN;
DR   A2ASS6, TITIN_MOUSE;  Q90ZY6, TLK1B_DANRE;  P34314, TLK1_CAEEL ;
DR   Q9UKI8, TLK1_HUMAN ;  Q8C0V0, TLK1_MOUSE ;  Q1ECX4, TLK2_DANRE ;
DR   Q86UE8, TLK2_HUMAN ;  O55047, TLK2_MOUSE ;  Q08CW1, TLK2_XENTR ;
DR   P43298, TMK1_ARATH ;  Q59H18, TNI3K_HUMAN;  Q5GIG6, TNI3K_MOUSE;
DR   Q5RF15, TNI3K_PONAB;  Q7TQP6, TNI3K_RAT  ;  Q9UKE5, TNIK_HUMAN ;
DR   P83510, TNIK_MOUSE ;  P35169, TOR1_YEAST ;  P32600, TOR2_YEAST ;
DR   Q9FR53, TOR_ARATH  ;  Q95Q95, TOR_CAEEL  ;  Q0DJS1, TOR_ORYSJ  ;
DR   A6ZU08, TOS3_YEAS7 ;  P43637, TOS3_YEAST ;  Q9NBK5, TRC_DROME  ;
DR   Q2LZZ7, TRC_DROPS  ;  Q1LUA6, TRIO_DANRE ;  O75962, TRIO_HUMAN ;
DR   Q0KL02, TRIO_MOUSE ;  Q9BX84, TRPM6_HUMAN;  Q8CIR4, TRPM6_MOUSE;
DR   Q96QT4, TRPM7_HUMAN;  Q923J1, TRPM7_MOUSE;  Q925B3, TRPM7_RAT  ;
DR   Q39238, TSL_ARATH  ;  Q3SZW1, TSSK1_BOVIN;  Q9BXA7, TSSK1_HUMAN;
DR   Q61241, TSSK1_MOUSE;  Q96PF2, TSSK2_HUMAN;  O54863, TSSK2_MOUSE;
DR   Q96PN8, TSSK3_HUMAN;  Q9D2E1, TSSK3_MOUSE;  Q6SA08, TSSK4_HUMAN;
DR   Q9D411, TSSK4_MOUSE;  Q8C1R0, TSSK5_MOUSE;  Q9BXA6, TSSK6_HUMAN;
DR   Q925K9, TSSK6_MOUSE;  Q55FT4, TSUA_DICDI ;  Q5TCY1, TTBK1_HUMAN;
DR   Q6PCN3, TTBK1_MOUSE;  Q6IQ55, TTBK2_HUMAN;  Q8TAS1, UHMK1_HUMAN;
DR   P97343, UHMK1_MOUSE;  Q5RCY1, UHMK1_PONAB;  Q63285, UHMK1_RAT  ;
DR   P28966, UL13_EHV1B ;  P84391, UL13_EHV1V ;  P04290, UL13_HHV11 ;
DR   P89436, UL13_HHV2H ;  Q6UDH7, UL13_PSHV1 ;  P30662, UL13_SUHVN ;
DR   P09296, UL13_VZVD  ;  Q6YP73, UL13_VZVO  ;  O75385, ULK1_HUMAN ;
DR   O70405, ULK1_MOUSE ;  Q8IYT8, ULK2_HUMAN ;  Q9QY01, ULK2_MOUSE ;
DR   Q5ZJH6, ULK3_CHICK ;  Q6PHR2, ULK3_HUMAN ;  Q3U3Q1, ULK3_MOUSE ;
DR   D3ZHP7, ULK3_RAT   ;  Q4V7Q6, ULK3_XENLA ;  Q96C45, ULK4_HUMAN ;
DR   Q3V129, ULK4_MOUSE ;  Q5R4M2, ULK4_PONAB ;  Q23551, UNC22_CAEEL;
DR   Q23023, UNC51_CAEEL;  Q08097, US03_BHV1S ;  Q04543, US03_CHV9D ;
DR   P28926, US03_EHV1B ;  P84390, US03_EHV1V ;  Q05101, US03_GAHVG ;
DR   Q9E6L8, US03_GAHVM ;  P04413, US03_HHV11 ;  P13287, US03_HHV2H ;
DR   Q6UDG0, US03_PSHV1 ;  P24381, US03_SUHVN ;  P09251, US03_VZVD  ;
DR   Q9J5B1, V111_FOWPN ;  Q9J523, V212_FOWPN ;  Q9J509, V226_FOWPN ;
DR   Q197F0, VF380_IIV3 ;  Q91FE4, VF380_IIV6 ;  Q03785, VHS1_YEAST ;
DR   O57252, VPK1_VACCA ;  P20505, VPK1_VACCC ;  P16913, VPK1_VACCW ;
DR   P33800, VPK1_VAR67 ;  P32216, VPK2_SWPVK ;  O57177, VPK2_VACCA ;
DR   P21095, VPK2_VACCC ;  P29884, VPK2_VACCP ;  Q9JFE5, VPK2_VACCT ;
DR   Q89121, VPK2_VACCW ;  P33801, VPK2_VAR67 ;  Q54S77, VPS15_DICDI;
DR   Q9UVG6, VPS15_PICPA;  P22219, VPS15_YEAST;  Q32PI1, VRK1_BOVIN ;
DR   A8WU31, VRK1_CAEBR ;  Q19848, VRK1_CAEEL ;  Q7ZUS1, VRK1_DANRE ;
DR   Q99986, VRK1_HUMAN ;  Q80X41, VRK1_MOUSE ;  Q86Y07, VRK2_HUMAN ;
DR   Q8BN21, VRK2_MOUSE ;  Q6B9X6, VWKA_DICDI ;  Q9VA38, WARTS_DROME;
DR   Q8RXE5, WNK10_ARATH;  Q6ICW6, WNK11_ARATH;  Q9CAV6, WNK1_ARATH ;
DR   Q9H4A3, WNK1_HUMAN ;  P83741, WNK1_MOUSE ;  A2YMV6, WNK1_ORYSI ;
DR   Q0D598, WNK1_ORYSJ ;  Q6R2V0, WNK1_PIG   ;  Q9JIH7, WNK1_RAT   ;
DR   Q8S8Y9, WNK2_ARATH ;  Q9Y3S1, WNK2_HUMAN ;  Q3UH66, WNK2_MOUSE ;
DR   Q65X23, WNK2_ORYSJ ;  Q9STK6, WNK3_ARATH ;  Q9BYP7, WNK3_HUMAN ;
DR   Q80XP9, WNK3_MOUSE ;  Q0D847, WNK3_ORYSJ ;  Q9LVL5, WNK4_ARATH ;
DR   Q96J92, WNK4_HUMAN ;  Q80UE6, WNK4_MOUSE ;  Q6EU49, WNK4_ORYSJ ;
DR   Q7TPK6, WNK4_RAT   ;  Q9SCU5, WNK5_ARATH ;  Q0D541, WNK5_ORYSJ ;
DR   Q8S8Y8, WNK6_ARATH ;  Q2RA93, WNK6_ORYSJ ;  Q8LST2, WNK7_ARATH ;
DR   Q2RBE3, WNK7_ORYSJ ;  Q944Q0, WNK8_ARATH ;  Q2QYL8, WNK8_ORYSJ ;
DR   Q2V338, WNK9_ARATH ;  Q2QXC6, WNK9_ORYSJ ;  Q54ZN3, Y0004_DICDI;
DR   Q54WW7, Y0010_DICDI;  Q54XY6, Y0019_DICDI;  Q54VV7, Y0111_DICDI;
DR   Q54Y90, Y0133_DICDI;  Q54XZ5, Y0138_DICDI;  Q55CA6, Y0146_DICDI;
DR   Q54FR9, Y0436_DICDI;  Q54RP7, Y0652_DICDI;  Q54IF2, Y0670_DICDI;
DR   Q54L81, Y0700_DICDI;  Q559T8, Y0701_DICDI;  O04086, Y1105_ARATH;
DR   Q9SXB3, Y1112_ARATH;  C0LGE4, Y1124_ARATH;  Q9SXB4, Y1130_ARATH;
DR   Q9SXB8, Y1133_ARATH;  Q54F40, Y1133_DICDI;  Q9SXB5, Y1135_ARATH;
DR   O64784, Y1136_ARATH;  O64783, Y1137_ARATH;  Q9LPZ3, Y1141_ARATH;
DR   O64778, Y1142_ARATH;  Q9M9S4, Y1143_ARATH;  O64776, Y1144_ARATH;
DR   O64774, Y1146_ARATH;  O64771, Y1148_ARATH;  Q9SYA0, Y1150_ARATH;
DR   Q3EDL4, Y1154_ARATH;  Q9SY95, Y1155_ARATH;  Q54JC7, Y1197_DICDI;
DR   Q54RZ7, Y1199_DICDI;  B3LFC0, Y1332_ARATH;  C0LGF5, Y1341_ARATH;
DR   Q9XID3, Y1343_ARATH;  Q9ZVM9, Y1461_ARATH;  Q9FX99, Y1497_ARATH;
DR   Q54EG9, Y1516_DICDI;  C0LGG4, Y1518_ARATH;  C0LGG7, Y1534_ARATH;
DR   Q1ZXI5, Y1558_DICDI;  C0LGH2, Y1561_ARATH;  C0LGD6, Y1570_ARATH;
DR   Q9LP24, Y1571_ARATH;  O64780, Y1614_ARATH;  C0LGH8, Y1634_ARATH;
DR   Q54FH3, Y1638_DICDI;  O64781, Y1639_ARATH;  Q54UZ1, Y1639_DICDI;
DR   O64777, Y1643_ARATH;  O64770, Y1649_ARATH;  Q9SY89, Y1661_ARATH;
DR   Q54EM1, Y1664_DICDI;  Q3ECH2, Y1670_ARATH;  O64793, Y1675_ARATH;
DR   C0LGI2, Y1677_ARATH;  Q9M9C5, Y1680_ARATH;  C0LGD7, Y1684_ARATH;
DR   C0LGI5, Y1699_ARATH;  Q9SHI2, Y1723_ARATH;  Q9CAH1, Y1725_ARATH;
DR   C0LGJ1, Y1743_ARATH;  C0LGD8, Y1755_ARATH;  C0LGD9, Y1756_ARATH;
DR   C0LGE0, Y1765_ARATH;  P0C5E2, Y1839_ARATH;  Q9SYM9, Y1853_ARATH;
DR   Q0V7T5, Y1864_ARATH;  Q9SAH3, Y1887_ARATH;  Q54DY0, Y1918_DICDI;
DR   Q9ASQ6, Y1972_ARATH;  Q8MYF1, Y2070_DICDI;  Q9ZQQ7, Y2144_ARATH;
DR   C0LGK4, Y2165_ARATH;  Q0WVM4, Y2239_ARATH;  Q9ZUI0, Y2241_ARATH;
DR   C0LGK9, Y2242_ARATH;  C0LGJ9, Y2278_ARATH;  C0LGL4, Y2289_ARATH;
DR   Q9SJG2, Y2296_ARATH;  O49318, Y2317_ARATH;  Q54DC8, Y2350_DICDI;
DR   Q3EBR4, Y2394_ARATH;  Q54SK3, Y2417_DICDI;  Q9ZQR3, Y2451_ARATH;
DR   O64639, Y2559_ARATH;  Q8SSH1, Y255_ENCCU ;  Q0KHT7, Y2666_DROME;
DR   O80719, Y2706_ARATH;  Q54SC4, Y2777_DICDI;  O81069, Y2899_ARATH;
DR   O64477, Y2913_ARATH;  O65924, Y2921_ARATH;  O64556, Y2923_ARATH;
DR   Q9SRH7, Y3130_ARATH;  C0LGN2, Y3148_ARATH;  Q9LRP3, Y3174_ARATH;
DR   Q8MYQ1, Y31E_CAEEL ;  Q54R98, Y3301_DICDI;  Q54R95, Y3337_DICDI;
DR   Q9LFG1, Y3359_ARATH;  Q9SNA3, Y3463_ARATH;  Q9SD62, Y3471_ARATH;
DR   C0LGP4, Y3475_ARATH;  Q8H186, Y3545_ARATH;  Q9SFT7, Y3707_ARATH;
DR   Q54B48, Y3958_DICDI;  Q8VYT3, Y4052_ARATH;  Q9SV83, Y4103_ARATH;
DR   Q9T058, Y4119_ARATH;  Q9ZR08, Y4230_ARATH;  C0LGQ7, Y4245_ARATH;
DR   Q54PX0, Y4251_DICDI;  C0LGR3, Y4265_ARATH;  C0LGR6, Y4291_ARATH;
DR   C0LGQ9, Y4294_ARATH;  C0LGR9, Y4312_ARATH;  Q8VZJ9, Y4330_ARATH;
DR   Q6NKZ9, Y4345_ARATH;  C0LGS2, Y4361_ARATH;  C0LGS3, Y4372_ARATH;
DR   Q54PK8, Y4491_DICDI;  Q944A7, Y4523_ARATH;  Q9STJ8, Y4539_ARATH;
DR   O81832, Y4729_ARATH;  Q8VZG8, Y4885_ARATH;  O23082, Y4960_ARATH;
DR   Q94C25, Y5005_ARATH;  Q8GXZ3, Y5102_ARATH;  Q9FHD7, Y5126_ARATH;
DR   C0LGT1, Y5129_ARATH;  Q9LFV3, Y5157_ARATH;  Q9LFP7, Y5158_ARATH;
DR   C0LGT5, Y5169_ARATH;  Q9FZB8, Y5181_ARATH;  C0LGG3, Y5182_ARATH;
DR   Q8LEB6, Y5185_ARATH;  Q9FZB1, Y5188_ARATH;  C0LGG6, Y5189_ARATH;
DR   Q9FLV4, Y5248_ARATH;  C0LGG8, Y5343_ARATH;  C0LGG9, Y5344_ARATH;
DR   Q8W4S5, Y5371_ARATH;  C0LGU1, Y5374_ARATH;  C0LGU5, Y5457_ARATH;
DR   C0LGU7, Y5458_ARATH;  C0LGV0, Y5487_ARATH;  C0LGX1, Y5524_ARATH;
DR   O65238, Y5537_ARATH;  Q9FM85, Y5564_ARATH;  Q9SI06, Y5573_ARATH;
DR   Q5XF57, Y5576_ARATH;  Q9FN93, Y5596_ARATH;  C0LGH3, Y5614_ARATH;
DR   Q9LVP0, Y5639_ARATH;  Q9LTC0, Y5707_ARATH;  Q9LT96, Y5977_ARATH;
DR   Q54ET3, Y6373_DICDI;  Q54E34, Y6398_DICDI;  Q86HW6, Y6461_DICDI;
DR   Q54LR6, Y6481_DICDI;  Q54LH8, Y6627_DICDI;  Q550K8, Y7071_DICDI;
DR   Q76P07, Y7165_DICDI;  Q1ZXR2, Y7566_DICDI;  Q54YZ5, Y7989_DICDI;
DR   Q54VU4, Y8013_DICDI;  Q55FV5, Y8550_DICDI;  Q55F45, Y8642_DICDI;
DR   Q54LU8, Y8646_DICDI;  Q54XJ4, Y8901_DICDI;  Q54V83, Y9296_DICDI;
DR   Q54C18, Y9452_DICDI;  Q55DK2, Y9628_DICDI;  Q54WD7, Y9719_DICDI;
DR   Q54V35, Y9841_DICDI;  Q54RR9, Y9844_DICDI;  Q55GG4, Y9847_DICDI;
DR   Q55A55, Y9848_DICDI;  Q54XX5, Y9849_DICDI;  Q869X3, Y9851_DICDI;
DR   Q86AE1, Y9853_DICDI;  Q54TH6, Y9863_DICDI;  Q54VC0, Y9865_DICDI;
DR   Q55BA0, Y9866_DICDI;  Q86HG9, Y9871_DICDI;  Q54QI2, Y9877_DICDI;
DR   Q55GU0, Y9955_DICDI;  Q55EI8, Y9956_DICDI;  Q552C1, Y9957_DICDI;
DR   Q55A09, Y9963_DICDI;  Q54C38, Y9988_DICDI;  O31435, YBDM_BACSU ;
DR   Q12222, YGK3_YEAST ;  P42169, YKL2_CAEEL ;  Q5UQ24, YL205_MIMIV;
DR   Q5UQC1, YL232_MIMIV;  Q5UPU3, YL268_MIMIV;  Q5UNT4, YL670_MIMIV;
DR   Q5UNT1, YL673_MIMIV;  P34516, YMX8_CAEEL ;  P34633, YOO1_CAEEL ;
DR   P34635, YOO3_CAEEL ;  P34649, YOT3_CAEEL ;  Q12152, YP150_YEAST;
DR   Q09437, YP62_CAEEL ;  P12688, YPK1_YEAST ;  P18961, YPK2_YEAST ;
DR   P38070, YPK3_YEAST ;  Q9RI12, YPKA_YERPE ;  Q05608, YPKA_YERPS ;
DR   Q5UPZ2, YR301_MIMIV;  Q5UQJ6, YR400_MIMIV;  Q7T6Y1, YR436_MIMIV;
DR   Q5UQ78, YR517_MIMIV;  Q5UNT7, YR679_MIMIV;  Q5UQG7, YR818_MIMIV;
DR   Q7T6X2, YR826_MIMIV;  Q7T6Y2, YR831_MIMIV;  Q09595, YRL5_CAEEL ;
DR   O32057, YRZF_BACSU ;  Q56UN5, YSK4_HUMAN ;  Q11090, YWY3_CAEEL ;
DR   Q621J7, ZYG1_CAEBR ;  Q9GT24, ZYG1_CAEEL ;
//
ID   2.7.11.2
DE   [Pyruvate dehydrogenase (acetyl-transferring)] kinase.
AN   PDH kinase.
AN   PDHK.
AN   PDK.
AN   Pyruvate dehydrogenase kinase.
AN   Pyruvate dehydrogenase kinase (phosphorylating).
CA   ATP + [pyruvate dehydrogenase (acetyl-transferring)] = ADP + [pyruvate
CA   dehydrogenase (acetyl-transferring)] phosphate.
CC   -!- Has no activating compound but is specific for its substrate.
CC   -!- A mitochondrial enzyme associated with the pyruvate dehydrogenase
CC       complex in mammals.
CC   -!- Phosphorylation inactivates EC 1.2.4.1.
CC   -!- Formerly EC 2.7.1.99.
PR   PROSITE; PDOC50109;
DR   Q02332, PDHK2_CAEEL;  Q15118, PDK1_HUMAN ;  Q8BFP9, PDK1_MOUSE ;
DR   Q63065, PDK1_RAT   ;  Q15119, PDK2_HUMAN ;  Q9JK42, PDK2_MOUSE ;
DR   Q64536, PDK2_RAT   ;  Q15120, PDK3_HUMAN ;  Q922H2, PDK3_MOUSE ;
DR   Q16654, PDK4_HUMAN ;  O70571, PDK4_MOUSE ;  O54937, PDK4_RAT   ;
DR   Q1KMR4, PDK4_RHIFE ;  O88345, PDK4_SPETR ;  O02623, PDK_ASCSU  ;
DR   P91622, PDK_DROME  ;  Q9P6P9, PDK_SCHPO  ;  P40530, PDK_YEAST  ;
DR   P53170, PKP2_YEAST ;
//
ID   2.7.11.3
DE   Dephospho-[reductase kinase] kinase.
AN   AMP-activated kinase.
AN   AMP-activated protein kinase kinase.
AN   Hydroxymethylglutaryl coenzyme A reductase kinase kinase.
AN   Reductase kinase.
AN   Reductase kinase kinase.
CA   ATP + dephospho-[[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase] =
CA   ADP + [[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase].
CC   -!- Activated by AMP and is specific for its substrate.
CC   -!- Phosphorylates and activates EC 2.7.11.31 which has been inactivated
CC       by EC 3.1.3.16.
CC   -!- Formerly EC 2.7.1.110.
//
ID   2.7.11.4
DE   [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase.
AN   BCK.
AN   BCKD kinase.
AN   BCODH kinase.
AN   Branched-chain 2-oxo acid dehydrogenase kinase.
AN   Branched-chain alpha-ketoacid dehydrogenase kinase.
AN   Branched-chain keto acid dehydrogenase kinase.
AN   Branched-chain oxo acid dehydrogenase kinase (phosphorylating).
CA   ATP + [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] =
CA   ADP + [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)]
CA   phosphate.
CC   -!- Has no activating compound but is specific for its substrate.
CC   -!- A mitochondrial enzyme associated with the branched-chain 2-oxoacid
CC       dehydrogenase complex.
CC   -!- Phosphorylation inactivates EC 1.2.4.4.
CC   -!- Formerly EC 2.7.1.115.
PR   PROSITE; PDOC50109;
DR   Q2KJG8, BCKD_BOVIN ;  O14874, BCKD_HUMAN ;  O55028, BCKD_MOUSE ;
DR   Q00972, BCKD_RAT   ;
//
ID   2.7.11.5
DE   [Isocitrate dehydrogenase (NADP(+))] kinase.
AN   ICDH kinase/phosphatase.
AN   IDH kinase.
AN   IDH kinase/phosphatase.
AN   IDH-K/P.
AN   IDHK/P.
AN   Isocitrate dehydrogenase kinase.
AN   Isocitrate dehydrogenase kinase (phosphorylating).
AN   Isocitrate dehydrogenase kinase/phosphatase.
CA   ATP + [isocitrate dehydrogenase (NADP(+))] = ADP + [isocitrate
CA   dehydrogenase (NADP(+))] phosphate.
CC   -!- Has no activating compound but is specific for its substrate.
CC   -!- Phosphorylates and inactivates EC 1.1.1.42.
CC   -!- Formerly EC 2.7.1.116.
DR   Q3IKY9, ACEK1_PSEHT;  Q3IHD9, ACEK2_PSEHT;  A1TVC1, ACEK_ACIAC ;
DR   A1WCB1, ACEK_ACISJ ;  A0KMM4, ACEK_AERHH ;  A4SQ71, ACEK_AERS4 ;
DR   Q2IJI0, ACEK_ANADE ;  A7HB82, ACEK_ANADF ;  Q5P801, ACEK_AROAE ;
DR   A1K4K7, ACEK_AZOSB ;  Q7WDP2, ACEK_BORBR ;  Q7W2P4, ACEK_BORPA ;
DR   B1YNR4, ACEK_BURA4 ;  Q1BT42, ACEK_BURCA ;  B1JZD3, ACEK_BURCC ;
DR   A0KAZ7, ACEK_BURCH ;  Q0BBE2, ACEK_BURCM ;  A9AE52, ACEK_BURM1 ;
DR   A3MNH1, ACEK_BURM7 ;  A2S7Q4, ACEK_BURM9 ;  Q62MX7, ACEK_BURMA ;
DR   A1V827, ACEK_BURMS ;  A3NQT1, ACEK_BURP0 ;  Q3JWQ8, ACEK_BURP1 ;
DR   A3N530, ACEK_BURP6 ;  B2JKI4, ACEK_BURP8 ;  B2SWU4, ACEK_BURPP ;
DR   Q63Y16, ACEK_BURPS ;  Q39CF3, ACEK_BURS3 ;  Q2T1P5, ACEK_BURTA ;
DR   A4JIA9, ACEK_BURVG ;  Q146J2, ACEK_BURXL ;  A8ANB7, ACEK_CITK8 ;
DR   Q487A4, ACEK_COLP3 ;  Q8KLU8, ACEK_CUPNH ;  Q477B5, ACEK_CUPPJ ;
DR   B2AG85, ACEK_CUPTR ;  Q47BD0, ACEK_DECAR ;  A7ZUN0, ACEK_ECO24 ;
DR   B7UPG7, ACEK_ECO27 ;  B7MIZ8, ACEK_ECO45 ;  B7LAV8, ACEK_ECO55 ;
DR   Q8X607, ACEK_ECO57 ;  B5Z0A8, ACEK_ECO5E ;  B7N2L5, ACEK_ECO81 ;
DR   B7M7S1, ACEK_ECO8A ;  C5A0V3, ACEK_ECOBW ;  B1XC15, ACEK_ECODH ;
DR   A8A7B3, ACEK_ECOHS ;  A1AII6, ACEK_ECOK1 ;  Q0TA53, ACEK_ECOL5 ;
DR   Q8FB61, ACEK_ECOL6 ;  B1IUN6, ACEK_ECOLC ;  P11071, ACEK_ECOLI ;
DR   B7NFV2, ACEK_ECOLU ;  B6I5M4, ACEK_ECOSE ;  B1LPH3, ACEK_ECOSM ;
DR   Q1R3T1, ACEK_ECOUT ;  A4W5D0, ACEK_ENT38 ;  A7MPD7, ACEK_ENTS8 ;
DR   Q6D012, ACEK_ERWCT ;  B7LKA4, ACEK_ESCF3 ;  Q5QWZ3, ACEK_IDILO ;
DR   B5XYC7, ACEK_KLEP3 ;  A6TGR8, ACEK_KLEP7 ;  A2SL82, ACEK_METPP ;
DR   C6DFQ3, ACEK_PECCP ;  Q7MZA0, ACEK_PHOLL ;  Q6LUQ1, ACEK_PHOPR ;
DR   A1VJF1, ACEK_POLNA ;  Q124G2, ACEK_POLSJ ;  Q15XV2, ACEK_PSEA6 ;
DR   A6V8H8, ACEK_PSEA7 ;  B7UVK3, ACEK_PSEA8 ;  Q02JM4, ACEK_PSEAB ;
DR   Q9I3W8, ACEK_PSEAE ;  Q1I6M7, ACEK_PSEE4 ;  Q4KGH6, ACEK_PSEF5 ;
DR   A4XT90, ACEK_PSEMY ;  A5W024, ACEK_PSEP1 ;  Q3KGE4, ACEK_PSEPF ;
DR   B0KS44, ACEK_PSEPG ;  Q88EA1, ACEK_PSEPK ;  B1JCS1, ACEK_PSEPW ;
DR   A4VMC4, ACEK_PSEU5 ;  Q1LS86, ACEK_RALME ;  B2UDV1, ACEK_RALPJ ;
DR   Q8Y2Q7, ACEK_RALSO ;  Q21RR4, ACEK_RHOFD ;  Q2J2X6, ACEK_RHOP2 ;
DR   Q6NCX0, ACEK_RHOPA ;  Q13E74, ACEK_RHOPS ;  B3Q986, ACEK_RHOPT ;
DR   B5F1J4, ACEK_SALA4 ;  Q57H42, ACEK_SALCH ;  B5FQM6, ACEK_SALDC ;
DR   B5QYG6, ACEK_SALEP ;  B5R7Q4, ACEK_SALG2 ;  B4TDG1, ACEK_SALHS ;
DR   B4T1M4, ACEK_SALNS ;  A9N0M7, ACEK_SALPB ;  C0Q489, ACEK_SALPC ;
DR   B4TQM3, ACEK_SALSV ;  Q8Z1V8, ACEK_SALTI ;  P51067, ACEK_SALTY ;
DR   A8GKF5, ACEK_SERP5 ;  B2TWJ8, ACEK_SHIB3 ;  Q31TY7, ACEK_SHIBS ;
DR   Q328N5, ACEK_SHIDS ;  Q8PFZ0, ACEK_XANAC ;  Q3BNH4, ACEK_XANC5 ;
DR   Q4UPY1, ACEK_XANC8 ;  B0RWU0, ACEK_XANCB ;  Q8P4D0, ACEK_XANCP ;
DR   A1JRX0, ACEK_YERE8 ;  A7FDG2, ACEK_YERP3 ;  Q1CC34, ACEK_YERPA ;
DR   Q8ZAR7, ACEK_YERPE ;  A9R541, ACEK_YERPG ;  Q1CNT1, ACEK_YERPN ;
DR   A4TH34, ACEK_YERPP ;  Q664W4, ACEK_YERPS ;
//
ID   2.7.11.6
DE   [Tyrosine 3-monooxygenase] kinase.
AN   Pheochromocytoma tyrosine hydroxylase-associated kinase.
AN   Tyrosine 3-monooxygenase kinase (phosphorylating).
CA   ATP + [tyrosine-3-monooxygenase] = ADP + [tyrosine-3-monooxygenase]
CA   phosphate.
CF   Magnesium.
CC   -!- Has no activating compound but is specific for its substrate, with
CC       which it copurifies.
CC   -!- Activates EC 1.14.16.2 by phosphorylation.
CC   -!- Formerly EC 2.7.1.124.
//
ID   2.7.11.7
DE   [Myosin heavy-chain] kinase.
AN   Calmodulin-dependent myosin heavy chain kinase.
AN   MHCK.
AN   MIHC kinase.
AN   Myosin heavy chain kinase.
AN   Myosin heavy chain kinase A.
AN   Myosin heavy-chain kinase.
AN   Myosin I heavy-chain kinase.
AN   Myosin II heavy-chain kinase.
CA   ATP + [myosin heavy-chain] = ADP + [myosin heavy-chain] phosphate.
CC   -!- The enzyme from Dictyostelium sp. (slime molds) brings about
CC       phosphorylation of the heavy chains of Dictyostelium myosin,
CC       inhibiting the actin-activated ATPase activity of the myosin.
CC   -!- One threonine residue in each heavy chain acts as acceptor.
CC   -!- While the enzyme from some species is activated by actin, in other
CC       cases Ca(2+)/calmodulin are required for activity.
CC   -!- Formerly EC 2.7.1.129.
PR   PROSITE; PDOC00100;
PR   PROSITE; PDOC51158;
DR   P42527, MHCKA_DICDI;  P90648, MHCKB_DICDI;  Q8MY12, MHCKC_DICDI;
DR   Q54SF9, MHCKD_DICDI;
//
ID   2.7.11.8
DE   Fas-activated serine/threonine kinase.
AN   FAST.
AN   FASTK.
CA   ATP + [Fas-activated serine/threonine protein] = ADP + [Fas-activated
CA   serine/threonine phosphoprotein].
CC   -!- This enzyme is activated during Fas-mediated apoptosis.
CC   -!- Following Fas ligation, the enzyme, which is constitutively
CC       phosphorylated, is dephosphorylated, and it is the dephosphorylated
CC       form that causes phosphorylation of TIA-1, a nuclear RNA-binding
CC       protein.
CC   -!- Phosphorylation of TIA-1 precedes the onset of DNA fragmentation.
DR   Q14296, FASTK_HUMAN;  Q9JIX9, FASTK_MOUSE;
//
ID   2.7.11.9
DE   [Goodpasture-antigen-binding protein] kinase.
AN   Goodpasture antigen-binding protein kinase.
AN   GPBP kinase.
AN   GPBPK.
CA   ATP + [Goodpasture antigen-binding protein] = ADP + [Goodpasture antigen-
CA   binding phosphoprotein].
CC   -!- This serine/threonine kinase specifically binds to and phosphorylates
CC       the N-terminal region of the human Goodpasture antigen, which is
CC       located on the alpha(3) chain of collagen IV and is involved in
CC       autoimmune disease.
//
ID   2.7.11.10
DE   I-kappa-B kinase.
AN   CHUK.
AN   IKBKA.
AN   IKBKB.
AN   IKK.
AN   IKK-1.
AN   IKK-2.
AN   Inhibitor of NF-kappa-B kinase.
AN   TANK-binding kinase 1.
AN   TBK1.
CA   ATP + [I-kappa-B protein] = ADP + [I-kappa-B phosphoprotein].
CC   -!- Phosphorylates I-kappa-B proteins at specific serine residues, which
CC       marks them for destruction via the ubiquitination pathway.
CC   -!- Subsequent degradation of the I-kappa-B complex (IKK) activates
CC       NF-kappa-B, a translation factor that plays an important role in
CC       inflammation, immunity, cell proliferation and apoptosis.
CC   -!- If the serine residues are replaced by threonine residues,
CC       the activity of the enzyme is decreased considerably.
PR   PROSITE; PDOC00100;
DR   Q95KV1, IKKA_BOVIN ;  Q5ZJB4, IKKA_CHICK ;  Q4G3H4, IKKA_DANRE ;
DR   O15111, IKKA_HUMAN ;  Q60680, IKKA_MOUSE ;  Q6GM53, IKKA_XENLA ;
DR   Q28DZ1, IKKA_XENTR ;  Q95KV0, IKKB_BOVIN ;  Q9VEZ5, IKKB_DROME ;
DR   O14920, IKKB_HUMAN ;  O88351, IKKB_MOUSE ;  Q9QY78, IKKB_RAT   ;
DR   Q14164, IKKE_HUMAN ;  Q9R0T8, IKKE_MOUSE ;
//
ID   2.7.11.11
DE   cAMP-dependent protein kinase.
AN   PKA.
AN   PKA C.
AN   Protein kinase A.
CA   ATP + a protein = ADP + a phosphoprotein.
CC   -!- cAMP is required to activate this enzyme.
CC   -!- The inactive holoenzyme of cAMP-dependent protein kinase is a
CC       tetramer composed of two regulatory (R) and two catalytic (C)
CC       subunits.
CC   -!- cAMP causes the dissociation of the inactive holoenzyme into a dimer
CC       of regulatory subunits bound to four cAMP molecules and two free
CC       monomeric catalytic subunits (i.e. R(2)C(2) + 4 cAMP = R(2)(cAMP)(4)
CC       + 2 C).
PR   PROSITE; PDOC00100;
DR   P06244, KAPA_YEAST ;  P40376, KAPB_SCHPO ;  P06245, KAPB_YEAST ;
DR   P00517, KAPCA_BOVIN;  Q8MJ44, KAPCA_CANFA;  P25321, KAPCA_CRIGR;
DR   P17612, KAPCA_HUMAN;  P05132, KAPCA_MOUSE;  P36887, KAPCA_PIG  ;
DR   P27791, KAPCA_RAT  ;  Q9MZD9, KAPCA_SHEEP;  P05131, KAPCB_BOVIN;
DR   P68180, KAPCB_CRIGR;  P22694, KAPCB_HUMAN;  P68181, KAPCB_MOUSE;
DR   P05383, KAPCB_PIG  ;  P68182, KAPCB_RAT  ;  P22612, KAPCG_HUMAN;
DR   O62846, KAPCG_MACMU;  P49673, KAPC_ASCSU ;  P21137, KAPC_CAEEL ;
DR   P34099, KAPC_DICDI ;  P12370, KAPC_DROME ;  Q8SRK8, KAPC_ENCCU ;
DR   P05986, KAPC_YEAST ;
//
ID   2.7.11.12
DE   cGMP-dependent protein kinase.
AN   3':5'-cyclic GMP-dependent protein kinase.
AN   cGMP-dependent protein kinase I-beta.
AN   Guanosine 3':5'-cyclic monophosphate-dependent protein kinase.
AN   PKG.
AN   PKG 1-alpha.
AN   PKG 1-beta.
AN   PKG II.
CA   ATP + a protein = ADP + a phosphoprotein.
CC   -!- cGMP is required to activate this enzyme.
CC   -!- The enzyme occurs as a dimer in higher eukaryotes.
CC   -!- The C-terminal region of each polypeptide chain contains the
CC       catalytic domain that includes the ATP and protein substrate binding
CC       sites.
CC   -!- This domain catalyzes the phosphorylation by ATP to specific serine
CC       or threonine residues in protein substrates.
CC   -!- The enzyme also has two allosteric cGMP-binding sites (sites A and
CC       B).
CC   -!- Binding of cGMP causes a conformational change that is associated
CC       with activation of the kinase.
PR   PROSITE; PDOC00100;
DR   A8X6H1, EGL4_CAEBR ;  O76360, EGL4_CAEEL ;  P00516, KGP1_BOVIN ;
DR   Q03042, KGP1_DROME ;  Q13976, KGP1_HUMAN ;  P0C605, KGP1_MOUSE ;
DR   O77676, KGP1_RABIT ;  Q03043, KGP24_DROME;  P32023, KGP25_DROME;
DR   Q13237, KGP2_HUMAN ;  Q61410, KGP2_MOUSE ;  Q64595, KGP2_RAT   ;
//
ID   2.7.11.13
DE   Protein kinase C.
AN   Calcium-dependent protein kinase C.
AN   Calcium-independent protein kinase C.
AN   Calcium/phospholipid dependent protein kinase.
AN   CPKC.
AN   NPKC.
AN   PKC.
CA   ATP + a protein = ADP + a phosphoprotein.
CC   -!- A family of serine- and threonine-specific protein kinases that
CC       depend on lipids for activity.
CC   -!- They can be activated by calcium but have a requirement for the
CC       second messenger diacylglycerol.
CC   -!- Members of this group of enzymes phosphorylate a wide variety of
CC       protein targets and are known to be involved in diverse cell-
CC       signaling pathways.
CC   -!- Members of the protein kinase C family also serve as major receptors
CC       for phorbol esters, a class of tumor promoters.
PR   PROSITE; PDOC00100;
DR   A8XWC4, DKF1_CAEBR ;  Q9XUJ7, DKF1_CAEEL ;  A8XQD5, DKF2_CAEBR ;
DR   O45818, DKF2_CAEEL ;  P34885, KPC1B_CAEEL;  Q16974, KPC1_APLCA ;
DR   Q00078, KPC1_ASPNG ;  P34722, KPC1_CAEEL ;  P43057, KPC1_CANAL ;
DR   O42632, KPC1_COCHE ;  P05130, KPC1_DROME ;  Q25378, KPC1_LYTPI ;
DR   P87253, KPC1_NEUCR ;  Q99014, KPC1_TRIRE ;  P24583, KPC1_YEAST ;
DR   Q16975, KPC2_APLCA ;  P90980, KPC2_CAEEL ;  P13677, KPC2_DROME ;
DR   A8WUG4, KPC3_CAEBR ;  Q19266, KPC3_CAEEL ;  P13678, KPC3_DROME ;
DR   P83099, KPC4_DROME ;  P04409, KPCA_BOVIN ;  P17252, KPCA_HUMAN ;
DR   P20444, KPCA_MOUSE ;  P10102, KPCA_RABIT ;  P05696, KPCA_RAT   ;
DR   P05126, KPCB_BOVIN ;  Q7SY24, KPCB_DANRE ;  P05771, KPCB_HUMAN ;
DR   P68404, KPCB_MOUSE ;  P05772, KPCB_RABIT ;  P68403, KPCB_RAT   ;
DR   Q7LZQ8, KPCB_XENLA ;  A8KBH6, KPCB_XENTR ;  Q15139, KPCD1_HUMAN;
DR   Q62101, KPCD1_MOUSE;  Q9WTQ1, KPCD1_RAT  ;  Q9BZL6, KPCD2_HUMAN;
DR   Q8BZ03, KPCD2_MOUSE;  Q5XIS9, KPCD2_RAT  ;  O94806, KPCD3_HUMAN;
DR   Q8K1Y2, KPCD3_MOUSE;  Q5PU49, KPCD_CANFA ;  Q05655, KPCD_HUMAN ;
DR   P28867, KPCD_MOUSE ;  P09215, KPCD_RAT   ;  Q02156, KPCE_HUMAN ;
DR   P16054, KPCE_MOUSE ;  P10830, KPCE_RABIT ;  P09216, KPCE_RAT   ;
DR   P05128, KPCG_BOVIN ;  P05129, KPCG_HUMAN ;  Q4R4U2, KPCG_MACFA ;
DR   P63318, KPCG_MOUSE ;  P10829, KPCG_RABIT ;  P63319, KPCG_RAT   ;
DR   Q90XF2, KPCI_DANRE ;  P41743, KPCI_HUMAN ;  Q62074, KPCI_MOUSE ;
DR   Q5R4K9, KPCI_PONAB ;  P24723, KPCL_HUMAN ;  P23298, KPCL_MOUSE ;
DR   Q64617, KPCL_RAT   ;  Q04759, KPCT_HUMAN ;  Q02111, KPCT_MOUSE ;
DR   Q9WTQ0, KPCT_RAT   ;  Q05513, KPCZ_HUMAN ;  Q02956, KPCZ_MOUSE ;
DR   O19111, KPCZ_RABIT ;  P09217, KPCZ_RAT   ;  P36582, PCK1_SCHPO ;
DR   P36583, PCK2_SCHPO ;  A1A4I4, PKN1_BOVIN ;  Q16512, PKN1_HUMAN ;
DR   P70268, PKN1_MOUSE ;  Q63433, PKN1_RAT   ;  Q16513, PKN2_HUMAN ;
DR   Q8BWW9, PKN2_MOUSE ;  O08874, PKN2_RAT   ;  Q6P5Z2, PKN3_HUMAN ;
DR   Q8K045, PKN3_MOUSE ;
//
ID   2.7.11.14
DE   Rhodopsin kinase.
AN   Cone opsin kinase.
AN   G-protein-coupled receptor kinase 1.
AN   GPCR kinase 1.
AN   Opsin kinase.
AN   Opsin kinase (phosphorylating).
AN   Rhodopsin kinase (phosphorylating).
AN   RK.
CA   ATP + [rhodopsin] = ADP + [rhodopsin] phosphate.
CC   -!- Acts on the bleached or activated form of rhodopsin.
CC   -!- Also phosphorylates the beta-adrenergic receptor, but more slowly.
CC   -!- Does not act on casein, histones or phosphovitin.
CC   -!- Inhibited by Zn(2+) and digitonin (cf. EC 2.7.11.15 and
CC       EC 2.7.11.16).
CC   -!- Formerly EC 2.7.1.97 and EC 2.7.1.125.
PR   PROSITE; PDOC00100;
DR   Q49HM9, GRK7A_DANRE;  B6CZ17, GRK7A_XENLA;  Q1XHL7, GRK7B_DANRE;
DR   B6CZ18, GRK7B_XENLA;  Q8WMV0, GRK7_BOVIN ;  Q8WTQ7, GRK7_HUMAN ;
DR   Q8WP15, GRK7_PIG   ;  Q9Z2G7, GRK7_SPETR ;  P28327, RK_BOVIN   ;
DR   Q15835, RK_HUMAN   ;  Q9WVL4, RK_MOUSE   ;  Q63651, RK_RAT     ;
//
ID   2.7.11.15
DE   [Beta-adrenergic-receptor] kinase.
AN   ADRBK1.
AN   Adrenergic receptor kinase.
AN   BARK1.
AN   Beta(2)ARK.
AN   Beta-adrenergic receptor-specific kinase.
AN   Beta-adrenergic-receptor kinase.
AN   Beta-adrenergic-receptor kinase (phosphorylating).
AN   Beta-adrenoceptor kinase.
AN   Beta-AR kinase.
AN   Beta-ARK.
AN   Beta-receptor kinase.
CA   ATP + [beta-adrenergic receptor] = ADP + [beta-adrenergic receptor]
CA   phosphate.
CC   -!- Acts on the agonist-occupied form of the receptor; also
CC       phosphorylates rhodopsin, but more slowly.
CC   -!- Does not act on casein or histones.
CC   -!- Inhibited by Zn(2+) and digitonin but is unaffected by cyclic-AMP
CC       (cf. EC 2.7.11.14 and EC 2.7.11.16).
CC   -!- Formerly EC 2.7.1.126.
PR   PROSITE; PDOC00100;
DR   P21146, ARBK1_BOVIN;  O97627, ARBK1_DIDMA;  P25098, ARBK1_HUMAN;
DR   Q64682, ARBK1_MESAU;  Q99MK8, ARBK1_MOUSE;  P26817, ARBK1_RAT  ;
DR   P26818, ARBK2_BOVIN;  P35626, ARBK2_HUMAN;  Q3UYH7, ARBK2_MOUSE;
DR   P26819, ARBK2_RAT  ;
//
ID   2.7.11.16
DE   [G-protein-coupled receptor] kinase.
AN   G protein-coupled receptor kinase.
AN   GPCR kinase.
AN   GPCRK.
CA   ATP + [G-protein-coupled receptor] = ADP + [G-protein-coupled receptor]
CA   phosphate.
CC   -!- All members of this enzyme subfamily possess a highly conserved
CC       binding site for 1-phosphatidylinositol 4,5-bisphosphate.
CC   -!- (cf. EC 2.7.11.14 and EC 2.7.11.15).
PR   PROSITE; PDOC00100;
DR   P32865, GPRK1_DROME;  P32866, GPRK2_DROME;  Q622Z7, GRK1_CAEBR ;
DR   Q09537, GRK1_CAEEL ;  Q09639, GRK2_CAEEL ;  P32298, GRK4_HUMAN ;
DR   O70291, GRK4_MOUSE ;  P70507, GRK4_RAT   ;  P43249, GRK5_BOVIN ;
DR   P34947, GRK5_HUMAN ;  Q8VEB1, GRK5_MOUSE ;  Q62833, GRK5_RAT   ;
DR   P43250, GRK6_HUMAN ;  O70293, GRK6_MOUSE ;  P97711, GRK6_RAT   ;
DR   Q49HM9, GRK7A_DANRE;  B6CZ17, GRK7A_XENLA;  Q1XHL7, GRK7B_DANRE;
DR   B6CZ18, GRK7B_XENLA;  Q8WMV0, GRK7_BOVIN ;  Q8WTQ7, GRK7_HUMAN ;
DR   Q8WP15, GRK7_PIG   ;  Q9Z2G7, GRK7_SPETR ;
//
ID   2.7.11.17
DE   Calcium/calmodulin-dependent protein kinase.
AN   Ca(2+)/calmodulin-dependent microtubule-associated protein 2 kinase.
AN   Ca(2+)/calmodulin-dependent protein kinase 1.
AN   Ca(2+)/calmodulin-dependent protein kinase II.
AN   Ca(2+)/calmodulin-dependent protein kinase IV.
AN   Ca(2+)/calmodulin-dependent protein kinase kinase.
AN   Ca(2+)/calmodulin-dependent protein kinase kinase beta.
AN   Calcium/calmodulin-dependent protein kinase type II.
AN   Caldesmon kinase.
AN   Caldesmon kinase (phosphorylating).
AN   Calmodulin-dependent kinase II.
AN   CaM kinase.
AN   CaM kinase II.
AN   CAM PKII.
AN   CaM-regulated serine/threonine kinase.
AN   CaMKI.
AN   CaMKII.
AN   CaMKIV.
AN   CaMKK-alpha.
AN   CaMKK-beta.
AN   Microtubule-associated protein 2 kinase.
CA   ATP + a protein = ADP + a phosphoprotein.
CF   Calcium.
CC   -!- Requires calmodulin.
CC   -!- A wide range of proteins can act as acceptor, including vimentin,
CC       synapsin, glycogen synthase, myosin light-chains and the microtubule-
CC       associated tau protein.
CC   -!- Not identical with EC EC 2.7.11.18 or EC 2.7.11.26.
CC   -!- Formerly EC 2.7.1.120 and EC 2.7.1.123.
PR   PROSITE; PDOC00100;
DR   Q10KY3, CAMK1_ORYSJ;  Q43531, CCAMK_LILLO;  A0AAR7, CCAMK_LOTJA;
DR   Q6RET7, CCAMK_MEDTR;  Q6AVM3, CCAMK_ORYSJ;  Q6RET6, CCAMK_PEA  ;
DR   A8X6H4, CMK1_CAEBR ;  Q9TXJ0, CMK1_CAEEL ;  Q24210, CSKP_DROME ;
DR   Q6DEH3, KC2D1_DANRE;  Q6DGS3, KC2D2_DANRE;  Q14012, KCC1A_HUMAN;
DR   Q91YS8, KCC1A_MOUSE;  Q63450, KCC1A_RAT  ;  Q6P2M8, KCC1B_HUMAN;
DR   Q9QYK9, KCC1B_MOUSE;  O70150, KCC1B_RAT  ;  Q8IU85, KCC1D_HUMAN;
DR   Q8BW96, KCC1D_MOUSE;  Q96NX5, KCC1G_HUMAN;  Q91VB2, KCC1G_MOUSE;
DR   Q7TNJ7, KCC1G_RAT  ;  Q00771, KCC1_EMENI ;  O14408, KCC1_METAN ;
DR   Q9P7I2, KCC1_SCHPO ;  P27466, KCC1_YEAST ;  Q00168, KCC2A_DROME;
DR   Q9UQM7, KCC2A_HUMAN;  P11798, KCC2A_MOUSE;  Q5RCC4, KCC2A_PONAB;
DR   P11275, KCC2A_RAT  ;  Q3MHJ9, KCC2B_BOVIN;  Q13554, KCC2B_HUMAN;
DR   P28652, KCC2B_MOUSE;  P08413, KCC2B_RAT  ;  Q2HJF7, KCC2D_BOVIN;
DR   A8WXF6, KCC2D_CAEBR;  O62305, KCC2D_CAEEL;  Q5ZKI0, KCC2D_CHICK;
DR   Q13557, KCC2D_HUMAN;  Q6PHZ2, KCC2D_MOUSE;  Q95266, KCC2D_PIG  ;
DR   O77708, KCC2D_RABIT;  P15791, KCC2D_RAT  ;  Q9DG02, KCC2D_XENLA;
DR   Q13555, KCC2G_HUMAN;  Q923T9, KCC2G_MOUSE;  P11730, KCC2G_RAT  ;
DR   O42844, KCC2_SCHPO ;  P22517, KCC2_YEAST ;  Q16566, KCC4_HUMAN ;
DR   P08414, KCC4_MOUSE ;  P13234, KCC4_RAT   ;  Q07250, KCCS_MALDO ;
DR   Q8N5S9, KKCC1_HUMAN;  Q8VBY2, KKCC1_MOUSE;  P97756, KKCC1_RAT  ;
DR   Q96RR4, KKCC2_HUMAN;  Q8C078, KKCC2_MOUSE;  O88831, KKCC2_RAT  ;
//
ID   2.7.11.18
DE   [Myosin light-chain] kinase.
AN   [Myosin-light-chain] kinase.
AN   Calcium/calmodulin-dependent myosin light chain kinase.
AN   MLCK.
AN   MLCkase.
AN   Myosin kinase.
AN   Myosin light chain kinase.
AN   Myosin light chain protein kinase.
AN   Myosin light-chain kinase.
AN   Myosin light-chain kinase (phosphorylating).
AN   Smooth-muscle-myosin-light-chain kinase.
CA   ATP + [myosin light-chain] = ADP + [myosin light-chain] phosphate.
CF   Calcium.
CC   -!- Requires calmodulin for activity.
CC   -!- The 20 kDa light chain from smooth muscle myosin is phosphorylated
CC       more rapidly than any other acceptor, but light chains from other
CC       myosins and myosin itself can act as acceptors, more slowly.
CC   -!- Formerly EC 2.7.1.117.
PR   PROSITE; PDOC00100;
DR   A4IFM7, MYLK2_BOVIN;  Q9H1R3, MYLK2_HUMAN;  Q8VCR8, MYLK2_MOUSE;
DR   P07313, MYLK2_RABIT;  P20689, MYLK2_RAT  ;  Q32MK0, MYLK3_HUMAN;
DR   Q3UIZ8, MYLK3_MOUSE;  Q5RDG7, MYLK3_PONAB;  P25323, MYLKA_DICDI;
DR   Q86AD7, MYLKB_DICDI;  Q54SJ5, MYLKC_DICDI;  Q54CY9, MYLKD_DICDI;
DR   Q54PB4, MYLKE_DICDI;  Q54W86, MYLKF_DICDI;  Q869W6, MYLKG_DICDI;
DR   Q28824, MYLK_BOVIN ;  P11799, MYLK_CHICK ;  Q15746, MYLK_HUMAN ;
DR   Q6PDN3, MYLK_MOUSE ;  P79280, MYLK_PIG   ;  P29294, MYLK_RABIT ;
DR   O02827, MYLK_SHEEP ;
//
ID   2.7.11.19
DE   Phosphorylase kinase.
AN   Dephosphophosphorylase kinase.
AN   Glycogen phosphorylase kinase.
AN   PHK.
AN   Phosphorylase b kinase.
AN   Phosphorylase B kinase.
AN   Phosphorylase kinase (phosphorylating).
CA   2 ATP + phosphorylase b = 2 ADP + phosphorylase a.
CF   Calcium.
CC   -!- Requires calmodulin for activity.
CC   -!- The enzyme phosphorylates a specific serine residue in each of the
CC       subunits of the dimeric phosphorylase b.
CC   -!- For muscle phosphorylase but not liver phosphorylase, this is
CC       accompanied by a further dimerization to form a tetrameric
CC       phosphorylase.
CC   -!- The enzyme couples muscle contraction with energy production via
CC       glycogenolysis--glycolysis by catalyzing the Ca(2+)-dependent
CC       phosphorylation and activation of glycogen phosphorylase b.
CC   -!- The gamma subunit of the tetrameric alpha-beta-gamma-delta enzyme is
CC       the catalytic subunit.
CC   -!- Formerly EC 2.7.1.38.
PR   PROSITE; PDOC00100;
DR   Q16816, PHKG1_HUMAN;  P07934, PHKG1_MOUSE;  P00518, PHKG1_RABIT;
DR   P13286, PHKG1_RAT  ;  Q2KJ16, PHKG2_BOVIN;  P15735, PHKG2_HUMAN;
DR   Q9DB30, PHKG2_MOUSE;  P31325, PHKG2_RAT  ;
//
ID   2.7.11.20
DE   [Elongation factor 2] kinase.
AN   Ca/CaM-kinase III.
AN   Calmodulin-dependent protein kinase III.
AN   CaM kinase III.
AN   EEF2 kinase.
AN   EEF2K.
AN   EF2K.
CA   ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate.
CF   Calcium.
CC   -!- Requires calmodulin for activity.
CC   -!- Can also be phosphorylated by the catalytic subunit of EC 2.7.11.11.
CC   -!- Elongation factor 2 is phosphorylated in several cell types in
CC       response to various growth factors, hormones and other stimuli that
CC       raise intracellular Ca(2+).
PR   PROSITE; PDOC51158;
DR   O01991, EF2K_CAEEL ;  O00418, EF2K_HUMAN ;  O08796, EF2K_MOUSE ;
DR   P70531, EF2K_RAT   ;
//
ID   2.7.11.21
DE   Polo kinase.
AN   PLK.
AN   Polo serine-threonine kinase.
AN   Polo-like kinase.
CA   ATP + a protein = ADP + a phosphoprotein.
CC   -!- The enzyme associates with the spindle pole during mitosis and is
CC       thought to play an important role in the dynamic function of the
CC       mitotic spindle during chromosome segregation.
CC   -!- The human form of the enzyme, Plk1, does not phosphorylate histone
CC       H1, enolase and phosvitin but it can phosphorylate myelin basic
CC       protein and microtubule-associated protein MAP-2, although to a
CC       lesser extent than casein.
PR   PROSITE; PDOC00100;
DR   P0C8M8, CCR1_MAIZE ;  Q8SWM6, CDC5_ENCCU ;  P32562, CDC5_YEAST ;
DR   Q2TA25, PLK1_BOVIN ;  P34331, PLK1_CAEEL ;  P53350, PLK1_HUMAN ;
DR   Q07832, PLK1_MOUSE ;  Q62673, PLK1_RAT   ;  P70032, PLK1_XENLA ;
DR   P62205, PLK1_XENTR ;  Q9N2L7, PLK2_CAEEL ;  Q9NYY3, PLK2_HUMAN ;
DR   P53351, PLK2_MOUSE ;  Q5R4L1, PLK2_PONAB ;  Q9R012, PLK2_RAT   ;
DR   Q20845, PLK3_CAEEL ;  Q9H4B4, PLK3_HUMAN ;  Q60806, PLK3_MOUSE ;
DR   Q9R011, PLK3_RAT   ;  Q16W24, PLK4_AEDAE ;  A2VDZ4, PLK4_BOVIN ;
DR   B0WAU8, PLK4_CULQU ;  Q7ZVS3, PLK4_DANRE ;  B3M6I4, PLK4_DROAN ;
DR   B3NE99, PLK4_DROER ;  B4J3F1, PLK4_DROGR ;  O97143, PLK4_DROME ;
DR   B4KYX8, PLK4_DROMO ;  B4HBU3, PLK4_DROPE ;  Q2LYK3, PLK4_DROPS ;
DR   B4IAQ8, PLK4_DROSE ;  B4QK53, PLK4_DROSI ;  B4LDJ6, PLK4_DROVI ;
DR   B4MXR8, PLK4_DROWI ;  B4PDM5, PLK4_DROYA ;  O00444, PLK4_HUMAN ;
DR   Q64702, PLK4_MOUSE ;  A7SNN5, PLK4_NEMVE ;  Q5R9Z7, PLK4_PONAB ;
DR   B2GUY1, PLK4_RAT   ;  Q6PAD2, PLK4_XENLA ;  B3DL84, PLK4_XENTR ;
DR   Q4FZD7, PLK5_MOUSE ;  P50528, PLO1_SCHPO ;  P52304, POLO_DROME ;
//
ID   2.7.11.22
DE   Cyclin-dependent kinase.
AN   Cdc2 kinase.
AN   Cdk-activating kinase.
AN   Cdk-activating protein kinase.
CA   ATP + a protein = ADP + a phosphoprotein.
CC   -!- Activation of cyclin-dependent kinases requires association of the
CC       enzyme with a regulatory subunit referred to as a cyclin.
CC   -!- It is the sequential activation and inactivation of cyclin-dependent
CC       kinases, through the periodic synthesis and destruction of cyclins,
CC       that provides the primary means of cell-cycle regulation.
PR   PROSITE; PDOC00100;
DR   Q75D46, BUR1_ASHGO ;  Q4WTN5, BUR1_ASPFU ;  Q9Y7W4, BUR1_CANAL ;
DR   Q6FQ83, BUR1_CANGA ;  Q6BV06, BUR1_DEBHA ;  Q96VK3, BUR1_EMENI ;
DR   Q4I5U9, BUR1_GIBZE ;  Q6CRA9, BUR1_KLULA ;  Q871M9, BUR1_NEUCR ;
DR   Q6C842, BUR1_YARLI ;  P23293, BUR1_YEAST ;  P43568, CAK1_YEAST ;
DR   P38973, CC2H1_TRYBB;  P54664, CC2H1_TRYCO;  P54665, CC2H2_TRYBB;
DR   P54666, CC2H3_TRYBB;  Q9UQ88, CD11A_HUMAN;  P21127, CD11B_HUMAN;
DR   P24923, CDC21_MEDSA;  P19026, CDC21_PEA  ;  Q05006, CDC22_MEDSA;
DR   P28567, CDC22_PEA  ;  Q38772, CDC2A_ANTMA;  Q38773, CDC2B_ANTMA;
DR   Q38774, CDC2C_ANTMA;  P23573, CDC2C_DROME;  Q38775, CDC2D_ANTMA;
DR   Q01917, CDC2H_CRIFA;  Q4Z6R1, CDC2H_PLABA;  Q4Y4B1, CDC2H_PLACH;
DR   P61075, CDC2H_PLAF7;  Q07785, CDC2H_PLAFK;  O96821, CDC2H_PLAKH;
DR   Q9XZD6, CDC2H_PLAVI;  Q7RM49, CDC2H_PLAYO;  Q26671, CDC2H_THEAN;
DR   Q27032, CDC2H_THEPA;  P93101, CDC2_CHERU ;  P23111, CDC2_MAIZE ;
DR   P43290, CDC2_PETHY ;  Q41639, CDC2_VIGAC ;  P52389, CDC2_VIGUN ;
DR   Q2TBL8, CDK10_BOVIN;  Q55GS4, CDK10_DICDI;  Q15131, CDK10_HUMAN;
DR   Q3UMM4, CDK10_MOUSE;  Q4KM47, CDK10_RAT  ;  Q54RB2, CDK11_DICDI;
DR   P24788, CDK11_MOUSE;  P46892, CDK11_RAT  ;  D2H526, CDK12_AILME;
DR   E1BB50, CDK12_BOVIN;  P46551, CDK12_CAEEL;  Q9VP22, CDK12_DROME;
DR   Q9NYV4, CDK12_HUMAN;  Q14AX6, CDK12_MOUSE;  Q3MJK5, CDK12_RAT  ;
DR   B5DE93, CDK12_XENTR;  E1BB52, CDK13_BOVIN;  Q14004, CDK13_HUMAN;
DR   Q69ZA1, CDK13_MOUSE;  B0VXE8, CDK14_CALJA;  B0VXL7, CDK14_CALMO;
DR   C0RW22, CDK14_DASNO;  O94921, CDK14_HUMAN;  O35495, CDK14_MOUSE;
DR   B6A7Q3, CDK14_RABIT;  Q6DJM7, CDK14_XENLA;  A4IIW7, CDK14_XENTR;
DR   Q1RLU9, CDK15_DANRE;  Q96Q40, CDK15_HUMAN;  Q3V3A1, CDK15_MOUSE;
DR   Q00536, CDK16_HUMAN;  Q04735, CDK16_MOUSE;  Q63686, CDK16_RAT  ;
DR   Q00537, CDK17_HUMAN;  Q8K0D0, CDK17_MOUSE;  O35831, CDK17_RAT  ;
DR   Q07002, CDK18_HUMAN;  Q04899, CDK18_MOUSE;  Q5RD01, CDK18_PONAB;
DR   Q9BWU1, CDK19_HUMAN;  Q8BWD8, CDK19_MOUSE;  P35567, CDK1A_XENLA;
DR   P24033, CDK1B_XENLA;  P54119, CDK1_AJECA ;  P48734, CDK1_BOVIN ;
DR   A8XA58, CDK1_CAEBR ;  P34556, CDK1_CAEEL ;  P43063, CDK1_CANAL ;
DR   P51958, CDK1_CARAU ;  P13863, CDK1_CHICK ;  P34112, CDK1_DICDI ;
DR   P23572, CDK1_DROME ;  Q00646, CDK1_EMENI ;  Q8SR86, CDK1_ENCCU ;
DR   P06493, CDK1_HUMAN ;  P11440, CDK1_MOUSE ;  Q9DGA5, CDK1_ORYCU ;
DR   Q9DGA2, CDK1_ORYJA ;  Q9DGD3, CDK1_ORYLA ;  Q9DG98, CDK1_ORYLU ;
DR   Q5RCH1, CDK1_PONAB ;  Q9W739, CDK1_RANDY ;  P39951, CDK1_RAT   ;
DR   P04551, CDK1_SCHPO ;  P00546, CDK1_YEAST ;  A8WIP6, CDK20_DANRE;
DR   Q8IZL9, CDK20_HUMAN;  Q5EDC3, CDK20_MACMU;  Q9JHU3, CDK20_MOUSE;
DR   Q5R7I7, CDK20_PONAB;  Q4KM34, CDK20_RAT  ;  Q5E9Y0, CDK2_BOVIN ;
DR   P43450, CDK2_CARAU ;  O55076, CDK2_CRIGR ;  Q04770, CDK2_ENTHI ;
DR   P24941, CDK2_HUMAN ;  P48963, CDK2_MESAU ;  P97377, CDK2_MOUSE ;
DR   Q63699, CDK2_RAT   ;  P23437, CDK2_XENLA ;  Q00526, CDK3_HUMAN ;
DR   Q80YP0, CDK3_MOUSE ;  Q32KY4, CDK4_BOVIN ;  P11802, CDK4_HUMAN ;
DR   P30285, CDK4_MOUSE ;  P79432, CDK4_PIG   ;  P35426, CDK4_RAT   ;
DR   B2MVY4, CDK4_SHEEP ;  Q91727, CDK4_XENLA ;  Q02399, CDK5_BOVIN ;
DR   P34117, CDK5_DICDI ;  P48609, CDK5_DROME ;  Q2PQN9, CDK5_GLOMM ;
DR   Q00535, CDK5_HUMAN ;  P49615, CDK5_MOUSE ;  Q03114, CDK5_RAT   ;
DR   P51166, CDK5_XENLA ;  Q00534, CDK6_HUMAN ;  Q64261, CDK6_MOUSE ;
DR   P51953, CDK7_CARAU ;  P54685, CDK7_DICDI ;  P50613, CDK7_HUMAN ;
DR   Q03147, CDK7_MOUSE ;  P51952, CDK7_RAT   ;  P20911, CDK7_XENLA ;
DR   Q17IE8, CDK8_AEDAE ;  P0C661, CDK8_CAEBR ;  P90866, CDK8_CAEEL ;
DR   Q8JH47, CDK8_DANRE ;  Q95YH0, CDK8_DICDI ;  Q9VT57, CDK8_DROME ;
DR   P49336, CDK8_HUMAN ;  Q8R3L8, CDK8_MOUSE ;  Q66KH9, CDK8_XENLA ;
DR   Q6P3N6, CDK8_XENTR ;  Q4V862, CDK9A_XENLA;  Q7ZX42, CDK9B_XENLA;
DR   Q5EAB2, CDK9_BOVIN ;  Q9TVL3, CDK9_CAEEL ;  Q5ZKN1, CDK9_CHICK ;
DR   P50750, CDK9_HUMAN ;  Q99J95, CDK9_MOUSE ;  Q641Z4, CDK9_RAT   ;
DR   Q96WV9, CDK9_SCHPO ;  Q6GLD8, CDK9_XENTR ;  P24100, CDKA1_ARATH;
DR   P29618, CDKA1_ORYSJ;  P29619, CDKA2_ORYSJ;  Q9LFT8, CDKC1_ARATH;
DR   Q6I5Y0, CDKC1_ORYSJ;  Q8W4P1, CDKC2_ARATH;  Q5JK68, CDKC2_ORYSJ;
DR   Q6ZAG3, CDKC3_ORYSJ;  Q9C9U2, CDKD1_ARATH;  A2Y4B6, CDKD1_ORYSI;
DR   P29620, CDKD1_ORYSJ;  Q9C9M7, CDKD2_ARATH;  Q9LMT0, CDKD3_ARATH;
DR   Q84TI6, CDKE1_ARATH;  Q336M2, CDKE1_ORYSJ;  O80345, CDKF1_ARATH;
DR   A2YCH5, CDKF1_ORYSI;  Q5Z754, CDKF1_ORYSJ;  Q2QSL4, CDKF2_ORYSJ;
DR   Q84SN3, CDKF3_ORYSJ;  Q6Z8C8, CDKF4_ORYSJ;  A2X6X1, CDKG1_ORYSI;
DR   Q6K5F8, CDKG1_ORYSJ;  A2XUW1, CDKG2_ORYSI;  Q7XUF4, CDKG2_ORYSJ;
DR   Q6AXJ9, CDKL1_DANRE;  Q00532, CDKL1_HUMAN;  Q8CEQ0, CDKL1_MOUSE;
DR   Q66HE7, CDKL1_RAT  ;  Q92772, CDKL2_HUMAN;  Q4R7T5, CDKL2_MACFA;
DR   Q9QUK0, CDKL2_MOUSE;  Q5R754, CDKL2_PONAB;  Q9TTK0, CDKL2_RABIT;
DR   Q5XIT0, CDKL2_RAT  ;  Q8IVW4, CDKL3_HUMAN;  Q4R8T9, CDKL3_MACFA;
DR   Q8BLF2, CDKL3_MOUSE;  Q9JM01, CDKL3_RAT  ;  Q5MAI5, CDKL4_HUMAN;
DR   Q3TZA2, CDKL4_MOUSE;  O76039, CDKL5_HUMAN;  Q3UTQ8, CDKL5_MOUSE;
DR   P25859, CKB11_ARATH;  Q8L4P8, CKB11_ORYSJ;  Q2V419, CKB12_ARATH;
DR   Q8LF80, CKB21_ARATH;  Q0J4I1, CKB21_ORYSJ;  Q8LG64, CKB22_ARATH;
DR   O35832, CKD18_RAT  ;  P36615, CSK1_SCHPO ;  Q9UPZ9, ICK_HUMAN  ;
DR   Q9JKV2, ICK_MOUSE  ;  Q62726, ICK_RAT    ;  Q9VPC0, KP58_DROME ;
DR   P20794, MAK_HUMAN  ;  Q04859, MAK_MOUSE  ;  P20793, MAK_RAT    ;
DR   P43294, MHK_ARATH  ;  Q9UQ07, MOK_HUMAN  ;  Q9WVS4, MOK_MOUSE  ;
DR   O74456, PEF1_SCHPO ;  Q751E8, PHO85_ASHGO;  Q9HGY5, PHO85_CANAL;
DR   Q6FKD4, PHO85_CANGA;  Q6BRY2, PHO85_DEBHA;  Q92241, PHO85_KLULA;
DR   Q6C7U8, PHO85_YARLI;  P17157, PHO85_YEAST;  Q12706, PSK1_SCHPO ;
DR   Q751F5, SSN3_ASHGO ;  A1CL96, SSN3_ASPCL ;  Q4WYR6, SSN3_ASPFU ;
DR   A2QU77, SSN3_ASPNC ;  Q2UC58, SSN3_ASPOR ;  Q0CQK1, SSN3_ASPTN ;
DR   Q5AHK2, SSN3_CANAL ;  Q6FKC6, SSN3_CANGA ;  Q2GYV9, SSN3_CHAGB ;
DR   Q1EBK0, SSN3_COCIM ;  P0CS77, SSN3_CRYNB ;  P0CS76, SSN3_CRYNJ ;
DR   Q6BM25, SSN3_DEBHA ;  Q5BAE1, SSN3_EMENI ;  Q4FCZ5, SSN3_GIBMO ;
DR   Q6CR51, SSN3_KLULA ;  A4QXX4, SSN3_MAGO7 ;  A1D624, SSN3_NEOFI ;
DR   Q0TWJ7, SSN3_PHANO ;  A3LUB9, SSN3_PICST ;  O13958, SSN3_SCHPO ;
DR   Q4P9T2, SSN3_USTMA ;  Q6CCB0, SSN3_YARLI ;  P39073, SSN3_YEAST ;
DR   Q54D75, Y2550_DICDI;  Q556J6, Y4007_DICDI;  Q55FJ6, Y8078_DICDI;
DR   Q8SRF5, Y823_ENCCU ;  Q54Y06, Y8487_DICDI;  Q8SR90, Y8H9_ENCCU ;
DR   Q8SQU8, YBC9_ENCCU ;
//
ID   2.7.11.23
DE   [RNA-polymerase]-subunit kinase.
AN   CTD kinase.
CA   ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase]
CA   phosphate.
CC   -!- Appears to be distinct from other protein phosphokinases.
CC   -!- Brings about multiple phosphorylation of the unique C-terminal repeat
CC       domain of the largest subunit of eukaryotic EC 2.7.7.6.
CC   -!- Does not phosphorylate casein, phosvitin or histone.
CC   -!- Formerly EC 2.7.1.141.
PR   PROSITE; PDOC00100;
DR   Q75D46, BUR1_ASHGO ;  Q4WTN5, BUR1_ASPFU ;  Q9Y7W4, BUR1_CANAL ;
DR   Q6FQ83, BUR1_CANGA ;  Q6BV06, BUR1_DEBHA ;  Q96VK3, BUR1_EMENI ;
DR   Q4I5U9, BUR1_GIBZE ;  Q6CRA9, BUR1_KLULA ;  Q871M9, BUR1_NEUCR ;
DR   Q6C842, BUR1_YARLI ;  P23293, BUR1_YEAST ;  P24923, CDC21_MEDSA;
DR   P19026, CDC21_PEA  ;  P28567, CDC22_PEA  ;  Q38772, CDC2A_ANTMA;
DR   Q38773, CDC2B_ANTMA;  Q38774, CDC2C_ANTMA;  P23573, CDC2C_DROME;
DR   Q38775, CDC2D_ANTMA;  Q01917, CDC2H_CRIFA;  Q4Z6R1, CDC2H_PLABA;
DR   Q4Y4B1, CDC2H_PLACH;  P61075, CDC2H_PLAF7;  Q07785, CDC2H_PLAFK;
DR   O96821, CDC2H_PLAKH;  Q9XZD6, CDC2H_PLAVI;  Q7RM49, CDC2H_PLAYO;
DR   Q26671, CDC2H_THEAN;  Q27032, CDC2H_THEPA;  P93101, CDC2_CHERU ;
DR   P23111, CDC2_MAIZE ;  P43290, CDC2_PETHY ;  Q41639, CDC2_VIGAC ;
DR   P52389, CDC2_VIGUN ;  D2H526, CDK12_AILME;  E1BB50, CDK12_BOVIN;
DR   P46551, CDK12_CAEEL;  Q9VP22, CDK12_DROME;  Q9NYV4, CDK12_HUMAN;
DR   Q14AX6, CDK12_MOUSE;  Q3MJK5, CDK12_RAT  ;  B5DE93, CDK12_XENTR;
DR   E1BB52, CDK13_BOVIN;  Q14004, CDK13_HUMAN;  Q69ZA1, CDK13_MOUSE;
DR   P35567, CDK1A_XENLA;  P24033, CDK1B_XENLA;  P54119, CDK1_AJECA ;
DR   P48734, CDK1_BOVIN ;  A8XA58, CDK1_CAEBR ;  P34556, CDK1_CAEEL ;
DR   P51958, CDK1_CARAU ;  P13863, CDK1_CHICK ;  P34112, CDK1_DICDI ;
DR   P23572, CDK1_DROME ;  Q00646, CDK1_EMENI ;  P06493, CDK1_HUMAN ;
DR   P11440, CDK1_MOUSE ;  Q9DGA5, CDK1_ORYCU ;  Q9DGA2, CDK1_ORYJA ;
DR   Q9DGD3, CDK1_ORYLA ;  Q9DG98, CDK1_ORYLU ;  Q5RCH1, CDK1_PONAB ;
DR   Q9W739, CDK1_RANDY ;  P39951, CDK1_RAT   ;  P04551, CDK1_SCHPO ;
DR   P51953, CDK7_CARAU ;  P54685, CDK7_DICDI ;  P50613, CDK7_HUMAN ;
DR   Q03147, CDK7_MOUSE ;  P51952, CDK7_RAT   ;  P20911, CDK7_XENLA ;
DR   Q17IE8, CDK8_AEDAE ;  P0C661, CDK8_CAEBR ;  P90866, CDK8_CAEEL ;
DR   Q8JH47, CDK8_DANRE ;  Q95YH0, CDK8_DICDI ;  Q9VT57, CDK8_DROME ;
DR   P49336, CDK8_HUMAN ;  Q8R3L8, CDK8_MOUSE ;  Q66KH9, CDK8_XENLA ;
DR   Q6P3N6, CDK8_XENTR ;  Q4V862, CDK9A_XENLA;  Q7ZX42, CDK9B_XENLA;
DR   Q5EAB2, CDK9_BOVIN ;  Q9TVL3, CDK9_CAEEL ;  Q5ZKN1, CDK9_CHICK ;
DR   P50750, CDK9_HUMAN ;  Q99J95, CDK9_MOUSE ;  Q641Z4, CDK9_RAT   ;
DR   Q96WV9, CDK9_SCHPO ;  Q6GLD8, CDK9_XENTR ;  P24100, CDKA1_ARATH;
DR   P29618, CDKA1_ORYSJ;  P29619, CDKA2_ORYSJ;  Q9LFT8, CDKC1_ARATH;
DR   Q6I5Y0, CDKC1_ORYSJ;  Q8W4P1, CDKC2_ARATH;  Q5JK68, CDKC2_ORYSJ;
DR   Q6ZAG3, CDKC3_ORYSJ;  Q9C9U2, CDKD1_ARATH;  A2Y4B6, CDKD1_ORYSI;
DR   P29620, CDKD1_ORYSJ;  Q9C9M7, CDKD2_ARATH;  Q9LMT0, CDKD3_ARATH;
DR   Q84TI6, CDKE1_ARATH;  Q336M2, CDKE1_ORYSJ;  O80345, CDKF1_ARATH;
DR   A2YCH5, CDKF1_ORYSI;  Q5Z754, CDKF1_ORYSJ;  Q2QSL4, CDKF2_ORYSJ;
DR   Q84SN3, CDKF3_ORYSJ;  Q6Z8C8, CDKF4_ORYSJ;  A2X6X1, CDKG1_ORYSI;
DR   Q6K5F8, CDKG1_ORYSJ;  A2XUW1, CDKG2_ORYSI;  Q7XUF4, CDKG2_ORYSJ;
DR   P25859, CKB11_ARATH;  Q8L4P8, CKB11_ORYSJ;  Q2V419, CKB12_ARATH;
DR   Q8LF80, CKB21_ARATH;  Q0J4I1, CKB21_ORYSJ;  Q8LG64, CKB22_ARATH;
DR   Q06309, CRK1_LEIME ;  Q12126, CRK1_SCHPO ;  Q8SQW2, CTK1_ENCCU ;
DR   O14098, CTK1_SCHPO ;  Q03957, CTK1_YEAST ;  Q8SW92, KIN28_ENCCU;
DR   P06242, KIN28_YEAST;  Q751F5, SSN3_ASHGO ;  A1CL96, SSN3_ASPCL ;
DR   Q4WYR6, SSN3_ASPFU ;  A2QU77, SSN3_ASPNC ;  Q2UC58, SSN3_ASPOR ;
DR   Q0CQK1, SSN3_ASPTN ;  Q5AHK2, SSN3_CANAL ;  Q6FKC6, SSN3_CANGA ;
DR   Q2GYV9, SSN3_CHAGB ;  Q1EBK0, SSN3_COCIM ;  P0CS77, SSN3_CRYNB ;
DR   P0CS76, SSN3_CRYNJ ;  Q6BM25, SSN3_DEBHA ;  Q5BAE1, SSN3_EMENI ;
DR   Q4FCZ5, SSN3_GIBMO ;  Q6CR51, SSN3_KLULA ;  A4QXX4, SSN3_MAGO7 ;
DR   A1D624, SSN3_NEOFI ;  Q0TWJ7, SSN3_PHANO ;  A3LUB9, SSN3_PICST ;
DR   O13958, SSN3_SCHPO ;  Q4P9T2, SSN3_USTMA ;  Q6CCB0, SSN3_YARLI ;
DR   P39073, SSN3_YEAST ;
//
ID   2.7.11.24
DE   Mitogen-activated protein kinase.
AN   C-Jun N-terminal kinase.
AN   ERK.
AN   Extracellular signal-regulated kinase.
AN   JNK.
AN   MAP kinase.
AN   MAPK.
AN   MBP kinase I.
AN   MBP kinase II.
AN   Microtubule-associated protein 2 kinase.
AN   Microtubule-associated protein kinase.
AN   Myelin basic protein kinase.
AN   SAPK.
AN   Stress-activated protein kinase.
CA   ATP + a protein = ADP + a phosphoprotein.
CC   -!- Phosphorylation of specific tyrosine and threonine residues in the
CC       activation loop of this enzyme by EC 2.7.12.2 is necessary for enzyme
CC       activation.
CC   -!- Once activated, the enzyme phosphorylates target substrates on serine
CC       or threonine residues followed by a proline.
CC   -!- A distinguishing feature of all MAPKs is the conserved sequence Thr-
CC       Xaa-Tyr (TXY).
CC   -!- Mitogen-activated protein kinase (MAPK) signal transduction pathways
CC       are among the most widespread mechanisms of cellular regulation.
CC   -!- Mammalian MAPK pathways can be recruited by a wide variety of stimuli
CC       including hormones (e.g. insulin and growth hormone), mitogens (e.g.
CC       epidermal growth factor and platelet-derived growth factor),
CC       vasoactive peptides (e.g. angiotensin-II and endothelin),
CC       inflammatory cytokines of the tumor necrosis factor (TNF) family and
CC       environmental stresses such as osmotic shock, ionizing radiation and
CC       ischemeic injury.
PR   PROSITE; PDOC00100;
PR   PROSITE; PDOC01049;
DR   P0CP67, CPK1_CRYNB ;  P0CP66, CPK1_CRYNJ ;  P28869, ERK1_CANAL ;
DR   P42525, ERK1_DICDI ;  Q54QB1, ERK2_DICDI ;  P40417, ERKA_DROME ;
DR   P16892, FUS3_YEAST ;  Q52PH6, HOG1_ALTBR ;  Q750A9, HOG1_ASHGO ;
DR   A1CPG7, HOG1_ASPCL ;  Q4WSF6, HOG1_ASPFU ;  A2QRF6, HOG1_ASPNC ;
DR   Q0D0P5, HOG1_ASPTN ;  Q6PWX2, HOG1_BEABA ;  Q702W0, HOG1_BLAAD ;
DR   Q8TGA9, HOG1_BLUGR ;  A1IVT7, HOG1_BOTFB ;  Q92207, HOG1_CANAL ;
DR   Q6FIU2, HOG1_CANGA ;  Q2H332, HOG1_CHAGB ;  Q4W6D3, HOG1_COCHE ;
DR   Q1DUU8, HOG1_COCIM ;  Q2WFL5, HOG1_COCMI ;  P0CP69, HOG1_CRYNB ;
DR   P0CP68, HOG1_CRYNJ ;  Q56R42, HOG1_CRYNV ;  Q875L0, HOG1_CRYPA ;
DR   Q9UV50, HOG1_DEBHA ;  Q9P419, HOG1_EMENI ;  Q38HL5, HOG1_EURHE ;
DR   Q4PNJ1, HOG1_FUSCU ;  Q4PKS0, HOG1_GIBIN ;  P0C431, HOG1_GIBZE ;
DR   Q75Q66, HOG1_GLOLA ;  Q8NJT7, HOG1_HORWE ;  Q6CJA8, HOG1_KLULA ;
DR   Q9UV51, HOG1_MAGO7 ;  Q1KTF2, HOG1_MYCGR ;  A1D2C9, HOG1_NEOFI ;
DR   Q96TL5, HOG1_NEUCR ;  Q0U4L8, HOG1_PHANO ;  A3LN91, HOG1_PICST ;
DR   Q09892, HOG1_SCHPO ;  Q5I6M2, HOG1_SETTU ;  Q1L5Z8, HOG1_TORDE ;
DR   Q6XKY3, HOG1_TRIAT ;  Q2WGK3, HOG1_TRIHA ;  Q4PC06, HOG1_USTMA ;
DR   A3EZ55, HOG1_WALIC ;  A3EZ53, HOG1_WALMU ;  A3EZ54, HOG1_WALSE ;
DR   Q6C4M9, HOG1_YARLI ;  P32485, HOG1_YEAST ;  O93982, HOG1_ZYGRC ;
DR   O59854, HOG1_ZYGRO ;  O59853, HOG2_ZYGRO ;  Q9U6D2, JNK1_ANCCA ;
DR   Q8WQG9, JNK1_CAEEL ;  P92208, JNK_DROME  ;  Q966Y3, JNK_SUBDO  ;
DR   P14681, KSS1_YEAST ;  O94737, MAPK1_PNECA;  O42781, MAPK2_PNECA;
DR   Q00859, MAPK_FUSSO ;  Q06060, MAPK_PEA   ;  Q40884, MAPK_PETHY ;
DR   P46196, MK01_BOVIN ;  P28482, MK01_HUMAN ;  P63085, MK01_MOUSE ;
DR   P63086, MK01_RAT   ;  P26696, MK01_XENLA ;  P27361, MK03_HUMAN ;
DR   Q63844, MK03_MOUSE ;  P21708, MK03_RAT   ;  P31152, MK04_HUMAN ;
DR   Q6P5G0, MK04_MOUSE ;  Q63454, MK04_RAT   ;  Q5F3W3, MK06_CHICK ;
DR   Q16659, MK06_HUMAN ;  Q61532, MK06_MOUSE ;  Q5R7U1, MK06_PONAB ;
DR   P27704, MK06_RAT   ;  A5PKJ4, MK07_BOVIN ;  Q13164, MK07_HUMAN ;
DR   Q9WVS8, MK07_MOUSE ;  P0C865, MK07_RAT   ;  Q90327, MK08A_CYPCA;
DR   O42099, MK08B_CYPCA;  Q9DGD9, MK08_DANRE ;  P45983, MK08_HUMAN ;
DR   Q91Y86, MK08_MOUSE ;  P49185, MK08_RAT   ;  Q8QHK8, MK08_XENLA ;
DR   P79996, MK09_CHICK ;  P45984, MK09_HUMAN ;  Q9WTU6, MK09_MOUSE ;
DR   P49186, MK09_RAT   ;  P53779, MK10_HUMAN ;  Q61831, MK10_MOUSE ;
DR   P49187, MK10_RAT   ;  Q15759, MK11_HUMAN ;  Q9WUI1, MK11_MOUSE ;
DR   O42376, MK12_DANRE ;  P53778, MK12_HUMAN ;  O08911, MK12_MOUSE ;
DR   Q63538, MK12_RAT   ;  Q3T0N5, MK13_BOVIN ;  O15264, MK13_HUMAN ;
DR   Q9Z1B7, MK13_MOUSE ;  Q9N272, MK13_PANTR ;  Q9WTY9, MK13_RAT   ;
DR   Q90336, MK14A_CYPCA;  Q9DGE2, MK14A_DANRE;  O62618, MK14A_DROME;
DR   Q9I958, MK14B_CYPCA;  Q9DGE1, MK14B_DANRE;  O61443, MK14B_DROME;
DR   P83100, MK14C_DROME;  O02812, MK14_CANFA ;  Q16539, MK14_HUMAN ;
DR   P47811, MK14_MOUSE ;  Q95NE7, MK14_PANTR ;  P70618, MK14_RAT   ;
DR   P47812, MK14_XENLA ;  Q8TD08, MK15_HUMAN ;  Q80Y86, MK15_MOUSE ;
DR   Q9Z2A6, MK15_RAT   ;  P43068, MKC1_CANAL ;  Q07176, MMK1_MEDSA ;
DR   Q40353, MMK2_MEDSA ;  Q9M1Z5, MPK10_ARATH;  Q5ZCI1, MPK10_ORYSJ;
DR   Q9LMM5, MPK11_ARATH;  Q5VN19, MPK11_ORYSJ;  Q8GYQ5, MPK12_ARATH;
DR   Q5Z9J0, MPK12_ORYSJ;  Q9LQQ9, MPK13_ARATH;  A2X0M1, MPK13_ORYSI;
DR   Q0E459, MPK13_ORYSJ;  O23236, MPK14_ARATH;  Q75KK8, MPK14_ORYSJ;
DR   Q9C9U4, MPK15_ARATH;  Q53N72, MPK15_ORYSJ;  Q8W4J2, MPK16_ARATH;
DR   Q5VP69, MPK16_ORYSJ;  Q84M93, MPK17_ARATH;  Q6L5F7, MPK17_ORYSJ;
DR   Q9C5C0, MPK18_ARATH;  Q9LUC3, MPK19_ARATH;  Q39021, MPK1_ARATH ;
DR   Q84UI5, MPK1_ORYSJ ;  Q9SJG9, MPK20_ARATH;  Q39022, MPK2_ARATH ;
DR   Q5J4W4, MPK2_ORYSJ ;  Q39023, MPK3_ARATH ;  Q6Z437, MPK3_ORYSJ ;
DR   Q39024, MPK4_ARATH ;  Q5Z859, MPK4_ORYSJ ;  Q39025, MPK5_ARATH ;
DR   A2XFC8, MPK5_ORYSI ;  Q10N20, MPK5_ORYSJ ;  Q39026, MPK6_ARATH ;
DR   Q336X9, MPK6_ORYSJ ;  Q39027, MPK7_ARATH ;  Q67C40, MPK7_ORYSJ ;
DR   Q9LM33, MPK8_ARATH ;  Q5SN53, MPK8_ORYSJ ;  Q9LV37, MPK9_ARATH ;
DR   Q6L5D4, MPK9_ORYSJ ;  A1CAF0, MPKC_ASPCL ;  Q4WUN7, MPKC_ASPFU ;
DR   A2QN07, MPKC_ASPNC ;  Q2U469, MPKC_ASPOR ;  Q0CIC7, MPKC_ASPTN ;
DR   Q9HG11, MPKC_EMENI ;  A1DES4, MPKC_NEOFI ;  Q8QGV6, NLK2_XENLA ;
DR   B1H3E1, NLK2_XENTR ;  A8XSC1, NLK_CAEBR  ;  Q9U9Y8, NLK_CAEEL  ;
DR   Q9UBE8, NLK_HUMAN  ;  O54949, NLK_MOUSE  ;  Q40517, NTF3_TOBAC ;
DR   Q40532, NTF4_TOBAC ;  Q40531, NTF6_TOBAC ;  Q17446, PMK1_CAEEL ;
DR   Q8MXI4, PMK2_CAEEL ;  O44514, PMK3_CAEEL ;  Q00772, SLT2_YEAST ;
DR   P41808, SMK1_YEAST ;  P27638, SPK1_SCHPO ;  Q92398, SPM1_SCHPO ;
DR   P39745, SUR1_CAEEL ;  Q11179, YPC2_CAEEL ;
//
ID   2.7.11.25
DE   Mitogen-activated protein kinase kinase kinase.
AN   MAP kinase kinase kinase.
AN   MAP3K.
AN   MAPKKK.
AN   MEK kinase.
AN   MEKK.
AN   MLK-like mitogen-activated protein triple kinase.
AN   MLTK.
CA   ATP + a protein = ADP + a phosphoprotein.
CC   -!- This enzyme phosphorylates and activates its downstream protein
CC       kinase, EC 2.7.12.2, but requires MAPKKKK for activation.
CC   -!- Some members of this family can be activated by p21-activated kinases
CC       (PAK/STE20) or Ras.
CC   -!- While c-Raf and c-Mos activate the classical MAPK/ERK pathway, MEKK1
CC       and MEKK2 preferentially activate the c-Jun N-terminal protein
CC       kinase(JNK)/stress-activated protein kinase (SAPK) pathway.
CC   -!- Mitogen-activated protein kinase (MAPK) signal transduction pathways
CC       are among the most widespread mechanisms of cellular regulation.
CC   -!- Mammalian MAPK pathways can be recruited by a wide variety of stimuli
CC       including hormones (e.g. insulin and growth hormone), mitogens (e.g.
CC       epidermal growth factor and platelet-derived growth factor),
CC       vasoactive peptides (e.g. angiotensin-II and endothelin),
CC       inflammatory cytokines of the tumor necrosis factor (TNF) family and
CC       environmental stresses such as osmotic shock, ionizing radiation and
CC       ischemeic injury.
PR   PROSITE; PDOC00100;
DR   O22040, ANP1_ARATH ;  P28829, BYR2_SCHPO ;  A8X775, DLK1_CAEBR ;
DR   O01700, DLK1_CAEEL ;  A7J1T2, M313A_XENLA;  A7J1T0, M313B_XENLA;
DR   Q02779, M3K10_HUMAN;  Q66L42, M3K10_MOUSE;  Q7T2V3, M3K10_XENLA;
DR   Q16584, M3K11_HUMAN;  Q80XI6, M3K11_MOUSE;  Q66HA1, M3K11_RAT  ;
DR   Q12852, M3K12_HUMAN;  Q60700, M3K12_MOUSE;  Q63796, M3K12_RAT  ;
DR   A7MBB4, M3K13_BOVIN;  O43283, M3K13_HUMAN;  Q1HKZ5, M3K13_MOUSE;
DR   Q5R8X7, M3K13_PONAB;  Q99558, M3K14_HUMAN;  Q9WUL6, M3K14_MOUSE;
DR   Q6ZN16, M3K15_HUMAN;  A2AQW0, M3K15_MOUSE;  Q39008, M3K1_ARATH ;
DR   Q13233, M3K1_HUMAN ;  P53349, M3K1_MOUSE ;  Q62925, M3K1_RAT   ;
DR   Q9FZ36, M3K2_ARATH ;  Q9Y2U5, M3K2_HUMAN ;  Q61083, M3K2_MOUSE ;
DR   O22042, M3K3_ARATH ;  Q99759, M3K3_HUMAN ;  Q61084, M3K3_MOUSE ;
DR   Q9Y6R4, M3K4_HUMAN ;  O08648, M3K4_MOUSE ;  Q99683, M3K5_HUMAN ;
DR   O35099, M3K5_MOUSE ;  O95382, M3K6_HUMAN ;  Q9WTR2, M3K6_MOUSE ;
DR   P83104, M3K7L_DROME;  A2VDU3, M3K7_BOVIN ;  Q9V3Q6, M3K7_DROME ;
DR   O43318, M3K7_HUMAN ;  Q62073, M3K7_MOUSE ;  Q5RFL3, M3K7_PONAB ;
DR   P0C8E4, M3K7_RAT   ;  P41279, M3K8_HUMAN ;  Q07174, M3K8_MOUSE ;
DR   Q63562, M3K8_RAT   ;  P80192, M3K9_HUMAN ;  Q3U1V8, M3K9_MOUSE ;
DR   Q5TCX8, M3KL4_HUMAN;  Q8VDG6, M3KL4_MOUSE;  Q95UN8, M3KSL_DROME;
DR   Q10407, MKH1_SCHPO ;  Q54R82, MKKA_DICDI ;  Q9NYL2, MLTK_HUMAN ;
DR   Q9ESL4, MLTK_MOUSE ;  A8WWX1, MOM4_CAEBR ;  Q9XTC6, MOM4_CAEEL ;
DR   P53599, SSK2_YEAST ;  O74304, WIN1_SCHPO ;  O14299, WIS4_SCHPO ;
//
ID   2.7.11.26
DE   [Tau protein] kinase.
AN   [Tau-protein] kinase.
AN   Glycogen synthase kinase-3-beta.
AN   GSK.
AN   Protein tau kinase.
AN   Tau kinase.
AN   Tau-tubulin kinase.
AN   TPK.
AN   TTK.
CA   ATP + [tau protein] = ADP + [tau protein] phosphate.
CC   -!- Activated by tubulin.
CC   -!- Involved in the formation of paired helical filaments, which are the
CC       main fibrous component of all fibrillary lesions in brain and are
CC       associated with Alzheimer's disease.
CC   -!- Formerly EC 2.7.1.135.
PR   PROSITE; PDOC00100;
DR   Q8TDC3, BRSK1_HUMAN;  Q5RJI5, BRSK1_MOUSE;  B2DD29, BRSK1_RAT  ;
DR   Q8IWQ3, BRSK2_HUMAN;  Q69Z98, BRSK2_MOUSE;  D3ZML2, BRSK2_RAT  ;
DR   Q55C57, GLKA_DICDI ;  P49840, GSK3A_HUMAN;  Q2NL51, GSK3A_MOUSE;
DR   P18265, GSK3A_RAT  ;  P49841, GSK3B_HUMAN;  Q9WV60, GSK3B_MOUSE;
DR   P18266, GSK3B_RAT  ;  Q5YJC2, GSK3B_SPECI;  Q388M1, GSK3B_TRYB2;
DR   Q91757, GSK3B_XENLA;  P83101, GSK3H_DROME;  A8X5H5, GSK3_CAEBR ;
DR   Q9U2Q9, GSK3_CAEEL ;  P51136, GSK3_DICDI ;
//
ID   2.7.11.27
DE   [Acetyl-CoA carboxylase] kinase.
AN   Acetyl coenzyme A carboxylase kinase (phosphorylating).
AN   Acetyl-CoA carboxylase bound kinase.
AN   Acetyl-CoA carboxylase kinase.
AN   Acetyl-CoA carboxylase kinase (AMP-activated).
AN   Acetyl-CoA carboxylase kinase (cAMP-independent).
AN   Acetyl-coenzyme A carboxylase kinase.
AN   AMPK.
AN   I-peptide kinase.
CA   ATP + [acetyl-CoA carboxylase] = ADP + [acetyl-CoA carboxylase]
CA   phosphate.
CC   -!- Phosphorylates and inactivates EC 6.4.1.2, which can be
CC       dephosphorylated and reactivated by EC 3.1.3.17.
CC   -!- More active toward the dimeric form of acetyl-CoA carboxylase than
CC       the polymeric form.
CC   -!- Phosphorylates serine residues.
CC   -!- Formerly EC 2.7.1.111 and EC 2.7.1.128.
//
ID   2.7.11.28
DE   Tropomyosin kinase.
AN   Tropomyosin kinase (phosphorylating).
CA   ATP + [tropomyosin] = ADP + [tropomyosin] phosphate.
CC   -!- Phosphorylates casein equally well, and histone and phosvitin to a
CC       lesser extent.
CC   -!- Formerly EC 2.7.1.132.
//
ID   2.7.11.29
DE   [Low-density-lipoprotein receptor] kinase.
AN   LDL receptor kinase.
AN   Low-density lipoprotein receptor kinase.
AN   Low-density-lipoprotein kinase.
AN   Low-density-lipoprotein receptor kinase (phosphorylating).
CA   ATP + [low-density-lipoprotein receptor] = ADP + [low-density-lipoprotein
CA   receptor] phosphate.
CC   -!- Phosphorylates the last serine residue (Ser-833) in the cytoplasmic
CC       domain of the low-density lipoprotein receptor.
CC   -!- Casein can also act as a substrate but with lower affinity.
CC   -!- GTP can act instead of ATP.
CC   -!- Formerly EC 2.7.1.131.
//
ID   2.7.11.30
DE   Receptor protein serine/threonine kinase.
AN   Activin receptor kinase.
AN   Receptor serine/threonine protein kinase.
AN   Receptor type I serine/threonine protein kinase.
AN   Receptor type II serine/threonine protein kinase.
AN   TGF-beta kinase.
CA   ATP + [receptor-protein] = ADP + [receptor-protein] phosphate.
CC   -!- The transforming growth factor beta (TGF-beta) family of cytokines
CC       regulates cell proliferation, differentiation, recognition and death.
CC   -!- Signaling occurs by the binding of ligand to the type II receptor,
CC       which is the constitutively active kinase.
CC   -!- Bound TGF-beta is then recognized by receptor I, which is
CC       phosphorylated and can propagate the signal to downstream substrates.
PR   PROSITE; PDOC00100;
DR   P36896, ACV1B_HUMAN;  Q61271, ACV1B_MOUSE;  P80202, ACV1B_RAT  ;
DR   Q8NER5, ACV1C_HUMAN;  Q8K348, ACV1C_MOUSE;  P70539, ACV1C_RAT  ;
DR   P37023, ACVL1_HUMAN;  Q61288, ACVL1_MOUSE;  Q5RAN0, ACVL1_PONAB;
DR   P80203, ACVL1_RAT  ;  Q28041, ACVR1_BOVIN;  Q90ZK6, ACVR1_CHICK;
DR   Q04771, ACVR1_HUMAN;  P37172, ACVR1_MOUSE;  P80201, ACVR1_RAT  ;
DR   Q16671, AMHR2_HUMAN;  Q8K592, AMHR2_MOUSE;  Q28616, AMHR2_RABIT;
DR   Q62893, AMHR2_RAT  ;  Q28043, AVR2A_BOVIN;  Q90669, AVR2A_CHICK;
DR   P27037, AVR2A_HUMAN;  P27038, AVR2A_MOUSE;  P38444, AVR2A_RAT  ;
DR   Q28560, AVR2A_SHEEP;  P27039, AVR2A_XENLA;  Q95126, AVR2B_BOVIN;
DR   Q90670, AVR2B_CHICK;  Q13705, AVR2B_HUMAN;  P27040, AVR2B_MOUSE;
DR   Q66T47, AVR2B_PIG  ;  P38445, AVR2B_RAT  ;  P27041, AVR2B_XENLA;
DR   Q13873, BMPR2_HUMAN;  O35607, BMPR2_MOUSE;  P36894, BMR1A_HUMAN;
DR   P36895, BMR1A_MOUSE;  Q78EA7, BMR1A_RAT  ;  Q05438, BMR1B_CHICK;
DR   O00238, BMR1B_HUMAN;  P36898, BMR1B_MOUSE;  P20792, DAF1_CAEEL ;
DR   P50488, DAF4_CAEEL ;  Q09488, SMA6_CAEEL ;  O46680, TGFR1_BOVIN;
DR   P36897, TGFR1_HUMAN;  Q64729, TGFR1_MOUSE;  Q5CD18, TGFR1_PIG  ;
DR   P80204, TGFR1_RAT  ;  Q90999, TGFR2_CHICK;  P37173, TGFR2_HUMAN;
DR   Q62312, TGFR2_MOUSE;  P38551, TGFR2_PIG  ;  P38438, TGFR2_RAT  ;
//
ID   2.7.11.31
DE   [Hydroxymethylglutaryl-CoA reductase (NADPH)] kinase.
AN   3-hydroxy-3-methylglutaryl coenzyme A reductase kinase.
AN   3-hydroxy-3-methylglutaryl-CoA reductase kinase.
AN   [Hydroxymethylglutaryl-CoA reductase (NADPH(2))] kinase.
AN   AMP-activated protein kinase.
AN   AMPK.
AN   Beta-hydroxy-beta-methylglutaryl-CoA reductase kinase.
AN   HMG-CoA reductase kinase.
AN   Hydroxymethylglutaryl coenzyme A reductase kinase.
AN   Hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating).
AN   Hydroxymethylglutaryl-CoA reductase kinase.
AN   Reductase kinase.
CA   ATP + [hydroxymethylglutaryl-CoA reductase (NADPH)] = ADP +
CA   [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate.
CC   -!- Activated by AMP.
CC   -!- EC 1.1.1.34 is inactivated by the phosphorylation of the enzyme
CC       protein.
CC   -!- Histones can also act as acceptors.
CC   -!- Can also phosphorylate EC 6.4.1.2 and EC 3.1.1.79.
CC   -!- Thr-172 within the catalytic subunit (alpha-subunit) is the major
CC       site phosphorylated by the AMP-activated protein kinase kinase.
CC   -!- GTP can act instead of ATP.
CC   -!- Formerly EC 2.7.1.109.
//
ID   2.7.12.1
DE   Dual-specificity kinase.
CA   ATP + a protein = ADP + a phosphoprotein.
CC   -!- This family of enzymes can phosphorylate both Ser/Thr and Tyr
CC       residues.
PR   PROSITE; PDOC00100;
DR   P51566, AFC1_ARATH ;  P51567, AFC2_ARATH ;  P51568, AFC3_ARATH ;
DR   P49759, CLK1_HUMAN ;  P22518, CLK1_MOUSE ;  P49760, CLK2_HUMAN ;
DR   O35491, CLK2_MOUSE ;  Q3SX21, CLK3_BOVIN ;  P49761, CLK3_HUMAN ;
DR   O35492, CLK3_MOUSE ;  Q63117, CLK3_RAT   ;  Q9HAZ1, CLK4_HUMAN ;
DR   O35493, CLK4_MOUSE ;  P49762, DOA_DROME  ;  Q1L6Q1, DUSTY_APIME;
DR   Q4TVR5, DUSTY_BOVIN;  Q4VSN4, DUSTY_CANFA;  Q6XUX0, DUSTY_CHICK;
DR   Q4VSN1, DUSTY_DANRE;  Q6XUX3, DUSTY_HUMAN;  Q20CR4, DUSTY_MACMU;
DR   Q6XUX1, DUSTY_MOUSE;  Q4VSN5, DUSTY_PANTR;  A2CI34, DUSTY_PIMPR;
DR   Q6XUX2, DUSTY_RAT  ;  A2CI35, DUSTY_STRPU;  Q4VSN2, DUSTY_TAKRU;
DR   Q4VSN3, DUSTY_TETNG;  Q67E01, DUSTY_XENLA;  Q67E00, DUSTY_XENTR;
DR   Q13627, DYR1A_HUMAN;  Q61214, DYR1A_MOUSE;  Q2TAE3, DYR1A_XENLA;
DR   Q0IJ08, DYR1A_XENTR;  Q9Y463, DYR1B_HUMAN;  Q9Z188, DYR1B_MOUSE;
DR   Q76NV1, DYRK1_DICDI;  Q5ZIU3, DYRK2_CHICK;  Q54BC9, DYRK2_DICDI;
DR   Q9V3D5, DYRK2_DROME;  Q92630, DYRK2_HUMAN;  Q5U4C9, DYRK2_MOUSE;
DR   P83102, DYRK3_DROME;  O43781, DYRK3_HUMAN;  Q4R6S5, DYRK3_MACFA;
DR   Q922Y0, DYRK3_MOUSE;  Q4V8A3, DYRK3_RAT  ;  Q9NR20, DYRK4_HUMAN;
DR   Q8BI55, DYRK4_MOUSE;  P32350, KNS1_YEAST ;  Q10156, LKH1_SCHPO ;
DR   A8X4H1, MBK1_CAEBR ;  Q8WQL7, MBK1_CAEEL ;  A8WJR8, MBK2_CAEBR ;
DR   Q9XTF3, MBK2_CAEEL ;  P49657, MNB_DROME  ;  Q09690, POM1_SCHPO ;
DR   Q54I36, PYK3_DICDI ;  Q552C6, PYK4_DICDI ;  Q15569, TESK1_HUMAN;
DR   O70146, TESK1_MOUSE;  Q63572, TESK1_RAT  ;  Q96S53, TESK2_HUMAN;
DR   Q8VCT9, TESK2_MOUSE;  Q924U5, TESK2_RAT  ;  Q8AYG3, TTK_DANRE  ;
DR   P33981, TTK_HUMAN  ;  Q4R945, TTK_MACFA  ;  P35761, TTK_MOUSE  ;
DR   Q8SQZ4, YAK1_ENCCU ;  P14680, YAK1_YEAST ;  Q54QV3, YAKA_DICDI ;
DR   Q75JK0, ZAKA_DICDI ;
//
ID   2.7.12.2
DE   Mitogen-activated protein kinase kinase.
AN   MAP kinase kinase.
AN   MAP2K.
AN   MAPKK.
AN   MEK.
AN   MKK.
CA   ATP + a protein = ADP + a phosphoprotein.
CC   -!- A dual-specific protein kinase and requires mitogen-activated protein
CC       kinase kinase kinase (MAPKKK) for activation.
CC   -!- It is required for activation of EC 2.7.11.24.
CC   -!- Phosphorylation of MEK1 by Raf involves phosphorylation of two serine
CC       residues.
CC   -!- Mitogen-activated protein kinase (MAPK) signal transduction pathways
CC       are among the most widespread mechanisms of cellular regulation.
CC   -!- Mammalian MAPK pathways can be recruited by a wide variety of stimuli
CC       including hormones (e.g. insulin and growth hormone), mitogens (e.g.
CC       epidermal growth factor and platelet-derived growth factor),
CC       vasoactive peptides (e.g. angiotensin-II and endothelin),
CC       inflammatory cytokines of the tumor necrosis factor (TNF) family and
CC       environmental stresses such as osmotic shock, ionizing radiation and
CC       ischemeic injury.
PR   PROSITE; PDOC00100;
DR   P10506, BYR1_SCHPO ;  Q24324, DSOR1_DROME;  P85051, DYR1A_RABIT;
DR   Q63470, DYR1A_RAT  ;  Q99078, FUZ7_USTMA ;  Q23977, HEP_DROME  ;
DR   Q94A06, M2K1_ARATH ;  Q5QN75, M2K1_ORYSJ ;  Q9S7U9, M2K2_ARATH ;
DR   O80397, M2K4_ARATH ;  Q8RXG3, M2K5_ARATH ;  Q9FJV0, M2K6_ARATH ;
DR   Q10664, MEK2_CAEEL ;  P32490, MKK1_YEAST ;  P32491, MKK2_YEAST ;
DR   Q20347, MKK4_CAEEL ;  Q63980, MP2K1_CRIGR;  Q55CL6, MP2K1_DICDI;
DR   Q02750, MP2K1_HUMAN;  P31938, MP2K1_MOUSE;  Q9XT09, MP2K1_PANTR;
DR   P29678, MP2K1_RABIT;  Q01986, MP2K1_RAT  ;  Q91447, MP2K1_SERCA;
DR   Q05116, MP2K1_XENLA;  Q1HG70, MP2K2_CANFA;  Q90891, MP2K2_CHICK;
DR   Q90321, MP2K2_CYPCA;  P36507, MP2K2_HUMAN;  Q63932, MP2K2_MOUSE;
DR   P36506, MP2K2_RAT  ;  Q07192, MP2K2_XENLA;  P46734, MP2K3_HUMAN;
DR   O09110, MP2K3_MOUSE;  P39746, MP2K3_XENLA;  P45985, MP2K4_HUMAN;
DR   P47809, MP2K4_MOUSE;  Q13163, MP2K5_HUMAN;  Q9WVS7, MP2K5_MOUSE;
DR   Q62862, MP2K5_RAT  ;  Q5E9X2, MP2K6_BOVIN;  Q9DGE0, MP2K6_DANRE;
DR   P52564, MP2K6_HUMAN;  P70236, MP2K6_MOUSE;  O14733, MP2K7_HUMAN;
DR   Q8CE90, MP2K7_MOUSE;  Q4KSH7, MP2K7_RAT  ;  O94235, MPH1_SCHPO ;
DR   Q8SSH4, MPS1_ENCCU ;  P54199, MPS1_YEAST ;  P08018, PBS2_YEAST ;
DR   Q9Y884, SKH1_SCHPO ;  P46599, STE7_CANAL ;  P06784, STE7_YEAST ;
DR   Q6DHU8, TOPK_DANRE ;  Q96KB5, TOPK_HUMAN ;  Q9JJ78, TOPK_MOUSE ;
DR   P33886, WIS1_SCHPO ;
//
ID   2.7.13.1
DE   Protein-histidine pros-kinase.
AN   Histidine kinase.
AN   Histidine protein kinase.
AN   HK2.
AN   Protein histidine kinase.
AN   Protein kinase (histidine).
CA   ATP + protein L-histidine = ADP + protein N(pi)-phospho-L-histidine.
CC   -!- A number of histones can act as acceptor.
CC   -!- Formerly EC 2.7.3.11.
//
ID   2.7.13.2
DE   Protein-histidine tele-kinase.
AN   Histidine kinase.
AN   Histidine protein kinase.
AN   HK3.
AN   Protein histidine kinase.
AN   Protein kinase (histidine).
CA   ATP + protein L-histidine = ADP + protein N(tau)-phospho-L-histidine.
CC   -!- A number of histones can act as acceptor.
CC   -!- Formerly EC 2.7.3.12.
//
ID   2.7.13.3
DE   Histidine kinase.
AN   Histidine protein kinase.
AN   HK1.
AN   Protein histidine kinase.
AN   Protein kinase.
AN   Protein kinase (histidine).
CA   ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
CC   -!- This entry has been included to accommodate those protein-histidine
CC       kinases for which the phosphorylation site has not been established
CC       (i.e. either the pros- or tele-nitrogen of histidine).
CC   -!- A number of histones can act as acceptor.
PR   PROSITE; PDOC50109;
DR   Q04943, AFSQ2_STRCO;  Q9SXL4, AHK1_ARATH ;  Q9C5U2, AHK2_ARATH ;
DR   Q9C5U1, AHK3_ARATH ;  Q9C5U0, AHK4_ARATH ;  Q3S4A7, AHK5_ARATH ;
DR   P58363, ARCB_ECO57 ;  P0AEC3, ARCB_ECOLI ;  P44578, ARCB_HAEIN ;
DR   P0AEC4, ARCB_SHIFL ;  Q2FH24, ARLS_STAA3 ;  Q9KJN3, ARLS_STAA8 ;
DR   Q2YY04, ARLS_STAAB ;  Q5HG05, ARLS_STAAC ;  Q7A2R7, ARLS_STAAM ;
DR   Q7A5N3, ARLS_STAAN ;  Q6GGZ4, ARLS_STAAR ;  Q6G9E7, ARLS_STAAS ;
DR   Q7A0W5, ARLS_STAAW ;  Q5HPC4, ARLS_STAEQ ;  Q8CSL7, ARLS_STAES ;
DR   Q4L6C5, ARLS_STAHJ ;  Q49XM6, ARLS_STAS1 ;  Q06067, ATOS_ECOLI ;
DR   P30847, BAES_ECOLI ;  P0AEC7, BARA_ECO57 ;  P0AEC6, BARA_ECOL6 ;
DR   P0AEC5, BARA_ECOLI ;  P59342, BARA_SHIFL ;  P30844, BASS_ECOLI ;
DR   P36557, BASS_SALTY ;  Q9K620, BCES_BACHD ;  O35044, BCES_BACSU ;
DR   Q9RZA4, BPHY_DEIRA ;  Q9HWR3, BPHY_PSEAE ;  P26762, BVGS_BORBR ;
DR   P40330, BVGS_BORPA ;  P16575, BVGS_BORPE ;  P29072, CHEA_BACSU ;
DR   Q44737, CHEA_BORBU ;  P07363, CHEA_ECOLI ;  P21813, CHEA_ENTAE ;
DR   Q92DW2, CHEA_LISIN ;  Q48768, CHEA_LISMO ;  Q52880, CHEA_RHIME ;
DR   Q53135, CHEA_RHOSH ;  P09384, CHEA_SALTY ;  Q56310, CHEA_THEMA ;
DR   P96123, CHEA_TREPA ;  Q07737, CHVG_AGRT5 ;  P72292, CHVG_RHIME ;
DR   P0A4I5, CIAH_STRPN ;  P0A4I6, CIAH_STRR6 ;  P52687, CITA_KLEPN ;
DR   Q9RC53, CITS_BACHD ;  O34427, CITS_BACSU ;  O22267, CKI1_ARATH ;
DR   Q99027, COMP_BACSU ;  Q02541, COPS_PSESM ;  P0AE84, CPXA_ECO57 ;
DR   P0AE83, CPXA_ECOL6 ;  P0AE82, CPXA_ECOLI ;  Q9KM66, CQSS_VIBCH ;
DR   A7N6S2, CQSS_VIBHB ;  P08401, CREC_ECOLI ;  Q82EB2, CSEC_STRAW ;
DR   Q9ZEP3, CSEC_STRCO ;  O32193, CSSS_BACSU ;  Q8XBY4, CUSS_ECO57 ;
DR   Q8FK37, CUSS_ECOL6 ;  P77485, CUSS_ECOLI ;  P0A4I7, CUTS_STRCO ;
DR   P0A4I8, CUTS_STRLI ;  Q44007, CZCS_RALME ;  P10047, DCTB_RHILE ;
DR   P13633, DCTB_RHIME ;  Q9K997, DCTS_BACHD ;  P96601, DCTS_BACSU ;
DR   P37739, DCTS_RHOCA ;  P0AEC9, DCUS_ECO57 ;  P59340, DCUS_ECOL6 ;
DR   P0AEC8, DCUS_ECOLI ;  P59341, DCUS_SHIFL ;  Q03069, DEGM_BACB2 ;
DR   P13799, DEGS_BACSU ;  P54663, DEGS_BREBE ;  O34757, DESK_BACSU ;
DR   P95194, DEVS_MYCTU ;  Q54U87, DHKA_DICDI ;  Q54YH4, DHKB_DICDI ;
DR   Q95PI2, DHKC_DICDI ;  Q54SP4, DHKD_DICDI ;  Q55E44, DHKE_DICDI ;
DR   Q551X9, DHKF_DICDI ;  Q54Q69, DHKG_DICDI ;  Q54W36, DHKH_DICDI ;
DR   Q86AT9, DHKI_DICDI ;  Q54YZ9, DHKJ_DICDI ;  Q86CZ2, DHKK_DICDI ;
DR   Q54RP6, DHKL_DICDI ;  Q54SK5, DHKM_DICDI ;  Q03228, DIVJ_CAUCR ;
DR   Q9RQQ9, DIVL_CAUCR ;  Q8E3C7, DLTS_STRA3 ;  Q8DXQ8, DLTS_STRA5 ;
DR   P77510, DPIB_ECOLI ;  P20169, DSPA_SYNY3 ;  P0AEJ4, ENVZ_ECOLI ;
DR   P41406, ENVZ_SALTI ;  P08982, ENVZ_SALTY ;  P0AEJ5, ENVZ_SHIFL ;
DR   Q38846, ERS1_ARATH ;  P49333, ETR1_ARATH ;  O49230, ETR1_BRAOL ;
DR   O82436, ETR1_CUCMN ;  Q9SSY6, ETR1_CUCSA ;  O81122, ETR1_MALDO ;
DR   Q9ZWL6, ETR1_PASED ;  Q9XH58, ETR1_PELHO ;  Q9M7M1, ETR1_PRUPE ;
DR   Q41342, ETR1_SOLLC ;  O48929, ETR1_TOBAC ;  Q9XH57, ETR2_PELHO ;
DR   O49187, ETR2_SOLLC ;  P58402, EVGS_ECO57 ;  P30855, EVGS_ECOLI ;
DR   P26489, FIXL_AZOC5 ;  P23222, FIXL_BRAJA ;  P10955, FIXL_RHIME ;
DR   P18769, FRZE_MYXXA ;  P48027, GACS_PSESY ;  P40758, GLNK_BACSU ;
DR   A7WZC5, GRAS_STAA1 ;  A6TZD7, GRAS_STAA2 ;  Q2FIX9, GRAS_STAA3 ;
DR   Q2G0D9, GRAS_STAA8 ;  A5IQL3, GRAS_STAA9 ;  Q2YSS1, GRAS_STAAB ;
DR   Q5HI08, GRAS_STAAC ;  A6QEW9, GRAS_STAAE ;  Q99VW1, GRAS_STAAM ;
DR   Q7A6Z3, GRAS_STAAN ;  Q6GJ10, GRAS_STAAR ;  Q6GBH0, GRAS_STAAS ;
DR   A8Z182, GRAS_STAAT ;  Q8NXR5, GRAS_STAAW ;  Q5HR80, GRAS_STAEQ ;
DR   Q8CTL4, GRAS_STAES ;  Q4L482, GRAS_STAHJ ;  Q49VK4, GRAS_STAS1 ;
DR   Q44930, GTCS_ANEMI ;  Q9AWA5, GWD1_SOLTU ;  Q7D9K1, HK12_MYCTU ;
DR   O07778, HK1_MYCTU  ;  O07777, HK2_MYCTU  ;  A7X5Y6, HSSS_STAA1 ;
DR   A6U489, HSSS_STAA2 ;  Q2FED4, HSSS_STAA3 ;  Q2FVQ8, HSSS_STAA8 ;
DR   A5IVE3, HSSS_STAA9 ;  Q2YZ23, HSSS_STAAB ;  Q5HDJ3, HSSS_STAAC ;
DR   A6QJK4, HSSS_STAAE ;  Q99RR5, HSSS_STAAM ;  Q7A3X0, HSSS_STAAN ;
DR   Q6GE72, HSSS_STAAR ;  Q6G6V8, HSSS_STAAS ;  A8Z553, HSSS_STAAT ;
DR   Q8NV46, HSSS_STAAW ;  Q5HLN1, HSSS_STAEQ ;  Q8CRA8, HSSS_STAES ;
DR   Q4L8M0, HSSS_STAHJ ;  Q49ZT9, HSSS_STAS1 ;  O31396, IRLS_BURPS ;
DR   P94608, KDPD_CLOAB ;  P21865, KDPD_ECOLI ;  P96372, KDPD_MYCTU ;
DR   O34971, KDPD_RATRA ;  P16497, KINA_BACSU ;  Q08430, KINB_BACSU ;
DR   O34206, KINB_PSEAE ;  P39764, KINC_BACSU ;  O31671, KIND_BACSU ;
DR   O31661, KINE_BACSU ;  O32198, LIAS_BACSU ;  B2SB67, LOVHK_BRUA1;
DR   Q2YKK7, LOVHK_BRUA2;  Q577Y7, LOVHK_BRUAB;  A9MBM8, LOVHK_BRUC2;
DR   Q8YC53, LOVHK_BRUME;  A5VUS1, LOVHK_BRUO2;  A9WYQ7, LOVHK_BRUSI;
DR   Q8FW73, LOVHK_BRUSU;  A6X554, LOVHK_OCHA4;  Q48IV1, LOVHK_PSE14;
DR   Q881J7, LOVHK_PSESM;  Q4ZSY3, LOVHK_PSEU2;  P0C5S6, LUXN_VIBHA ;
DR   A7MRY4, LUXN_VIBHB ;  Q9KLK7, LUXQ_VIBCH ;  P54302, LUXQ_VIBHA ;
DR   Q87GU5, LUXQ_VIBPA ;  Q8D5Z6, LUXQ_VIBVU ;  Q7MD16, LUXQ_VIBVY ;
DR   Q2NCA3, LVHK1_ERYLH;  Q2NB77, LVHK2_ERYLH;  Q81JL2, LYTS_BACAN ;
DR   Q814J0, LYTS_BACCR ;  P94513, LYTS_BACSU ;  Q82Z75, LYTS_ENTFA ;
DR   Q8EQQ2, LYTS_OCEIH ;  Q2FK10, LYTS_STAA3 ;  Q53705, LYTS_STAA8 ;
DR   Q2YV68, LYTS_STAAB ;  Q5HJB6, LYTS_STAAC ;  P60612, LYTS_STAAM ;
DR   P60613, LYTS_STAAN ;  Q6GK52, LYTS_STAAR ;  Q6GCL2, LYTS_STAAS ;
DR   P60614, LYTS_STAAW ;  Q5HLG3, LYTS_STAEQ ;  Q8CR79, LYTS_STAES ;
DR   Q4L8V3, LYTS_STAHJ ;  Q4A009, LYTS_STAS1 ;  Q8E7H4, LYTS_STRA3 ;
DR   Q8E218, LYTS_STRA5 ;  Q8DVB6, LYTS_STRMU ;  Q9P7Q7, MAK1_SCHPO ;
DR   O14002, MAK2_SCHPO ;  O74539, MAK3_SCHPO ;  O05250, MALK_BACSU ;
DR   A0QBR0, MPRB_MYCA1 ;  Q7U0X3, MPRB_MYCBO ;  A1KHB8, MPRB_MYCBP ;
DR   Q9Z5G7, MPRB_MYCLE ;  Q742C0, MPRB_MYCPA ;  A0R3I7, MPRB_MYCS2 ;
DR   A3Q5L8, MPRB_MYCSJ ;  A1UL69, MPRB_MYCSK ;  Q1B3X9, MPRB_MYCSS ;
DR   A5U124, MPRB_MYCTA ;  O53895, MPRB_MYCTU ;  A0PWB3, MPRB_MYCUA ;
DR   A1TEL6, MPRB_MYCVP ;  P59963, MTRB_MYCBO ;  Q9CCJ1, MTRB_MYCLE ;
DR   Q93CB7, MTRB_MYCPA ;  Q50496, MTRB_MYCTU ;  P27896, NARQ_ECOLI ;
DR   P44604, NARQ_HAEIN ;  O53857, NARS_MYCTU ;  P0AFA3, NARX_ECO57 ;
DR   P0AFA2, NARX_ECOLI ;  P0AFA4, NARX_SHIFL ;  Q3T0Q4, NDKB_BOVIN ;
DR   Q50KA8, NDKB_CANFA ;  P22392, NDKB_HUMAN ;  Q01768, NDKB_MOUSE ;
DR   Q2EN76, NDKB_PIG   ;  Q5RFH3, NDKB_PONAB ;  P19804, NDKB_RAT   ;
DR   P30663, NIFL_AZOVI ;  P42707, NISK_LACLA ;  P15939, NODV_BRAJA ;
DR   A7X624, NREB_STAA1 ;  A6U4C1, NREB_STAA2 ;  Q2FEA5, NREB_STAA3 ;
DR   Q2FVM6, NREB_STAA8 ;  A5IVH3, NREB_STAA9 ;  Q2YZ41, NREB_STAAB ;
DR   Q5HDG4, NREB_STAAC ;  A6QJN2, NREB_STAAE ;  Q931F6, NREB_STAAM ;
DR   Q99RN7, NREB_STAAN ;  Q6GE41, NREB_STAAR ;  Q6G6S9, NREB_STAAS ;
DR   A8Z581, NREB_STAAT ;  Q7A028, NREB_STAAW ;  Q7WZY5, NREB_STACT ;
DR   Q5HLK5, NREB_STAEQ ;  Q8CR97, NREB_STAES ;  Q4L8Q7, NREB_STAHJ ;
DR   P45670, NTRB_AZOBR ;  P10578, NTRB_BRASR ;  P0AFB6, NTRB_ECO57 ;
DR   P0AFB5, NTRB_ECOLI ;  P06218, NTRB_KLEOX ;  P28788, NTRB_PROHU ;
DR   P41503, NTRB_RHILP ;  Q52977, NTRB_RHIME ;  P09431, NTRB_RHOCB ;
DR   P0A2E0, NTRB_SALTI ;  P0A2D9, NTRB_SALTY ;  P0AFB7, NTRB_SHIFL ;
DR   P19906, NTRB_VIBAL ;  Q1RJB3, NTRYL_RICBR;  Q92H24, NTRYL_RICCN;
DR   Q4UMD4, NTRYL_RICFE;  Q9ZCU7, NTRYL_RICPR;  Q68WC5, NTRYL_RICTY;
DR   P45675, NTRY_AZOBR ;  Q04850, NTRY_AZOC5 ;  Q47457, PCOS_ECOLX ;
DR   B2S758, PDHS_BRUA1 ;  Q2YRB4, PDHS_BRUA2 ;  Q57BR6, PDHS_BRUAB ;
DR   A9M715, PDHS_BRUC2 ;  Q8YIM6, PDHS_BRUME ;  A5VRX4, PDHS_BRUO2 ;
DR   B0CI82, PDHS_BRUSI ;  Q8FZ86, PDHS_BRUSU ;  A6X5X4, PDHS_OCHA4 ;
DR   O05846, PDTAS_MYCTU;  Q04804, PFES_PSEAE ;  P37433, PGTB_SALTY ;
DR   Q8X739, PHOQ_ECO57 ;  Q8FIB8, PHOQ_ECOL6 ;  P23837, PHOQ_ECOLI ;
DR   Q57QC4, PHOQ_SALCH ;  Q5PMJ0, PHOQ_SALPA ;  Q8Z7H3, PHOQ_SALTI ;
DR   P14147, PHOQ_SALTY ;  Q83RR1, PHOQ_SHIFL ;  P23545, PHOR_BACSU ;
DR   P08400, PHOR_ECOLI ;  P71380, PHOR_HAEIN ;  P45608, PHOR_KLEPN ;
DR   P23621, PHOR_PSEAE ;  P45609, PHOR_SHIDY ;  Q55168, PHY1_SYNY3 ;
DR   Q9LCC2, PHYA_NOSS1 ;  Q9R6X3, PHYB_NOSS1 ;  P33639, PILS_PSEAE ;
DR   P37894, PLEC_CAUCR ;  Q70FG9, PMRB_PECCC ;  P0A5Z9, PRRB_MYCBO ;
DR   O33071, PRRB_MYCLE ;  P0A5Z8, PRRB_MYCTU ;  Q8X524, QSEC_ECO57 ;
DR   P40719, QSEC_ECOLI ;  P45336, QSEC_HAEIN ;  Q8Z3P2, QSEC_SALTI ;
DR   Q8ZLZ9, QSEC_SALTY ;  P14376, RCSC_ECOLI ;  Q56128, RCSC_SALTI ;
DR   P58662, RCSC_SALTY ;  P39838, RCSD_ECOLI ;  Q3J6C1, REGB_RHOS4 ;
DR   P0C0Z0, REGB_RHOSH ;  P35164, RESE_BACSU ;  P0C0F7, RPFC_XANC8 ;
DR   P0C0F6, RPFC_XANCP ;  Q08408, RPRX_BACFR ;  Q8GP19, RSSA_SERMA ;
DR   P18392, RSTB_ECOLI ;  Q2FIT5, SAES_STAA3 ;  Q2G2U1, SAES_STAA8 ;
DR   Q2YSM6, SAES_STAAB ;  Q5HHW5, SAES_STAAC ;  Q840P7, SAES_STAAE ;
DR   Q99VR8, SAES_STAAM ;  Q7A6V4, SAES_STAAN ;  Q6GIT7, SAES_STAAR ;
DR   Q6GBC5, SAES_STAAS ;  Q7A1J2, SAES_STAAW ;  Q5HR29, SAES_STAEQ ;
DR   Q8CTI3, SAES_STAES ;  Q8YR50, SASA_NOSS1 ;  Q7BWI3, SASA_PROMA ;
DR   Q7V6P7, SASA_PROMM ;  Q7V113, SASA_PROMP ;  Q06904, SASA_SYNE7 ;
DR   Q7U871, SASA_SYNPX ;  Q55630, SASA_SYNY3 ;  Q8DMT2, SASA_THEEB ;
DR   P0A601, SENX3_MYCBO;  A0QR01, SENX3_MYCS2;  P0A600, SENX3_MYCTU;
DR   P54883, SEX3_MYCLE ;  Q9ZHD4, SILS_SALTY ;  P39928, SLN1_YEAST ;
DR   P33113, SPAK_BACSU ;  P39664, SPHS_SYNE7 ;  Q2FY80, SRRB_STAA8 ;
DR   Q5HFT1, SRRB_STAAC ;  Q99TZ9, SRRB_STAAM ;  Q7A5H7, SRRB_STAAN ;
DR   Q6GGK7, SRRB_STAAR ;  Q6G973, SRRB_STAAS ;  Q9L523, SRRB_STAAU ;
DR   Q8NWF3, SRRB_STAAW ;  O69729, TCRY_MYCTU ;  Q9P896, TCSA_EMENI ;
DR   Q9P4U6, TCSB_EMENI ;  P58356, TORS_ECO57 ;  P39453, TORS_ECOLI ;
DR   P09835, UHPB_ECOLI ;  P27668, UHPB_SALTY ;  Q47745, VANS_ENTFA ;
DR   Q06240, VANS_ENTFC ;  P07167, VIRAL_RHIRD;  P07168, VIRAW_RHIRD;
DR   P18540, VIRA_AGRT5 ;  P10799, VIRA_AGRT9 ;  Q9KWK8, VRAS_STAA1 ;
DR   Q5HEN9, VRAS_STAAC ;  Q7A2Q0, VRAS_STAAM ;  Q99SZ7, VRAS_STAAN ;
DR   Q6GFH2, VRAS_STAAR ;  Q6G849, VRAS_STAAS ;  Q7A0H9, VRAS_STAAW ;
DR   Q5HN49, VRAS_STAEQ ;  Q8CRV2, VRAS_STAES ;  Q4L7J6, VRAS_STAHJ ;
DR   Q49YT0, VRAS_STAS1 ;  A7WWQ7, WALK_STAA1 ;  A6TXG9, WALK_STAA2 ;
DR   Q2FKN7, WALK_STAA3 ;  Q2G2U4, WALK_STAA8 ;  A5INR0, WALK_STAA9 ;
DR   Q2YUQ2, WALK_STAAB ;  Q5HJX6, WALK_STAAC ;  A6QD58, WALK_STAAE ;
DR   Q7A305, WALK_STAAM ;  Q7A8E0, WALK_STAAN ;  Q6GKS6, WALK_STAAR ;
DR   Q6GD71, WALK_STAAS ;  A8YYU2, WALK_STAAT ;  Q9RDT3, WALK_STAAU ;
DR   Q7A215, WALK_STAAW ;  Q5HK19, WALK_STAEQ ;  Q8CU87, WALK_STAES ;
DR   Q4LAJ8, WALK_STAHJ ;  Q4A159, WALK_STAS1 ;  A5A2P0, WALK_STASR ;
DR   Q52969, Y1002_RHIME;  Q2YV55, Y162_STAAB ;  Q8CU03, Y166_STAES ;
DR   Q2G1E0, Y185_STAA8 ;  Q6GCQ2, Y199_STAAS ;  Q8NYJ8, Y199_STAAW ;
DR   Q5HJF6, Y202_STAAC ;  Q6GK92, Y215_STAAR ;  Q7A7X8, Y216_STAAN ;
DR   Q2FK46, Y218_STAA3 ;  Q99WZ9, Y224_STAAM ;  Q5HKE1, Y2405_STAEQ;
DR   Q02482, Y3689_SHEFN;  O31433, YBDK_BACSU ;  P42245, YCBM_BACSU ;
DR   P70954, YCCG_BACSU ;  P51392, YCF26_PORPU;  Q1XD95, YCF26_PORYE;
DR   P94414, YCLK_BACSU ;  P96685, YDFH_BACSU ;  P76339, YEDV_ECOLI ;
DR   O31516, YESM_BACSU ;  P52101, YFHK_ECOLI ;  P94438, YFIJ_BACSU ;
DR   O07527, YHCY_BACSU ;  O34638, YKOH_BACSU ;  P54444, YRKQ_BACSU ;
DR   O06979, YVCQ_BACSU ;  Q795K2, YVFT_BACSU ;  O34989, YVRG_BACSU ;
DR   P42422, YXDK_BACSU ;  P55183, YXJM_BACSU ;  Q45614, YYCG_BACSU ;
DR   Q8X614, ZRAS_ECO57 ;  P14377, ZRAS_ECOLI ;  Q9APE0, ZRAS_KLEOX ;
DR   Q8Z332, ZRAS_SALTI ;  P37461, ZRAS_SALTY ;
//
ID   2.7.99.1
DE   Triphosphate--protein phosphotransferase.
AN   Diphosphate--protein phosphotransferase.
AN   DiPPT.
AN   Pyrophosphate-protein phosphotransferase.
CA   Triphosphate + [microsomal-membrane protein] = diphosphate + [microsomal-
CA   membrane protein] phosphate.
CC   -!- This enzyme was originally thought to use diphosphate as substrate
CC       but this has since been disproved.
CC   -!- The activity is observed as the second part of a biphasic reaction
CC       after depletion of ATP.
CC   -!- Tripolyphosphate is a contaminant of (gamma-(32)P)ATP.
CC   -!- Formerly EC 2.7.1.104.
//
ID   2.8.1.1
DE   Thiosulfate sulfurtransferase.
AN   Rhodanese.
AN   Thiosulfate cyanide transsulfurase.
AN   Thiosulfate thiotransferase.
CA   Thiosulfate + cyanide = sulfite + thiocyanate.
CC   -!- A few other sulfur compounds can act as donors.
PR   PROSITE; PDOC00322;
DR   A3MYF1, GLPE_ACTP2 ;  B3GZR9, GLPE_ACTP7 ;  B0BRY5, GLPE_ACTPJ ;
DR   Q6T893, GLPE_ACTPL ;  A6VKH3, GLPE_ACTSZ ;  A0KEH8, GLPE_AERHH ;
DR   B6ENU6, GLPE_ALISL ;  A8AQX5, GLPE_CITK8 ;  B6J836, GLPE_COXB1 ;
DR   B6J185, GLPE_COXB2 ;  A9NC75, GLPE_COXBR ;  Q83DV5, GLPE_COXBU ;
DR   A7ZSV5, GLPE_ECO24 ;  B7UKC9, GLPE_ECO27 ;  B7MDQ1, GLPE_ECO45 ;
DR   B7L4V4, GLPE_ECO55 ;  Q8X6Z5, GLPE_ECO57 ;  B5YUH7, GLPE_ECO5E ;
DR   B7NMI9, GLPE_ECO7I ;  B7N157, GLPE_ECO81 ;  B7M2I5, GLPE_ECO8A ;
DR   C4ZVX6, GLPE_ECOBW ;  B1X770, GLPE_ECODH ;  A8A5N3, GLPE_ECOHS ;
DR   A1AGU8, GLPE_ECOK1 ;  Q0TC43, GLPE_ECOL5 ;  P0A6V6, GLPE_ECOL6 ;
DR   B1IP41, GLPE_ECOLC ;  P0A6V5, GLPE_ECOLI ;  B7NE29, GLPE_ECOLU ;
DR   B6I2Y8, GLPE_ECOSE ;  B1LI85, GLPE_ECOSM ;  C5B970, GLPE_EDWI9 ;
DR   A4WFK9, GLPE_ENT38 ;  Q6CZL2, GLPE_ERWCT ;  B2VJU2, GLPE_ERWT9 ;
DR   B7LSC7, GLPE_ESCF3 ;  Q7VNZ0, GLPE_HAEDU ;  Q4QMN7, GLPE_HAEI8 ;
DR   A5UE38, GLPE_HAEIE ;  A5UHG8, GLPE_HAEIG ;  P44819, GLPE_HAEIN ;
DR   B8F6J5, GLPE_HAEPS ;  B5XTR4, GLPE_KLEP3 ;  A6TF44, GLPE_KLEP7 ;
DR   Q65QH0, GLPE_MANSM ;  Q9CL12, GLPE_PASMU ;  C6DH73, GLPE_PECCP ;
DR   Q7N9W3, GLPE_PHOLL ;  Q6LVT0, GLPE_PHOPR ;  B4EZM9, GLPE_PROMH ;
DR   Q48NU0, GLPE_PSE14 ;  Q15ZU3, GLPE_PSEA6 ;  A6UZ93, GLPE_PSEA7 ;
DR   B7V4H5, GLPE_PSEA8 ;  Q02TH4, GLPE_PSEAB ;  Q9I5U8, GLPE_PSEAE ;
DR   Q1IG23, GLPE_PSEE4 ;  Q4K4X2, GLPE_PSEF5 ;  C3K330, GLPE_PSEFS ;
DR   Q3IHW1, GLPE_PSEHT ;  A4XZJ7, GLPE_PSEMY ;  A5VXJ2, GLPE_PSEP1 ;
DR   Q3K5S9, GLPE_PSEPF ;  B0KJ90, GLPE_PSEPG ;  Q88QT9, GLPE_PSEPK ;
DR   B1JE10, GLPE_PSEPW ;  Q88A49, GLPE_PSESM ;  Q4ZMG2, GLPE_PSEU2 ;
DR   A4VHH7, GLPE_PSEU5 ;  B5F8P1, GLPE_SALA4 ;  A9MMA6, GLPE_SALAR ;
DR   Q57IV0, GLPE_SALCH ;  B5FKE4, GLPE_SALDC ;  B5R384, GLPE_SALEP ;
DR   B4TKV1, GLPE_SALHS ;  B4SVM2, GLPE_SALNS ;  Q5PLZ7, GLPE_SALPA ;
DR   A9MTU1, GLPE_SALPB ;  B5BHH6, GLPE_SALPK ;  B4TY78, GLPE_SALSV ;
DR   P64252, GLPE_SALTI ;  P64251, GLPE_SALTY ;  A8GKU1, GLPE_SERP5 ;
DR   Q8E8J2, GLPE_SHEON ;  B2U3N3, GLPE_SHIB3 ;  Q31VK8, GLPE_SHIBS ;
DR   Q32AN7, GLPE_SHIDS ;  Q0SZP1, GLPE_SHIF8 ;  P0A6V7, GLPE_SHIFL ;
DR   Q3YWA3, GLPE_SHISS ;  Q2NQH2, GLPE_SODGM ;  C4L7X3, GLPE_TOLAT ;
DR   A5F4G9, GLPE_VIBC3 ;  Q9KVP1, GLPE_VIBCH ;  C3LPU2, GLPE_VIBCM ;
DR   Q5E203, GLPE_VIBF1 ;  B5FCB8, GLPE_VIBFM ;  A7MXX7, GLPE_VIBHB ;
DR   Q87KM5, GLPE_VIBPA ;  B7VMA4, GLPE_VIBSL ;  Q8DD53, GLPE_VIBVU ;
DR   Q7MQ91, GLPE_VIBVY ;  A7FNW5, GLPE_YERP3 ;  Q1C2L3, GLPE_YERPA ;
DR   B2K5W3, GLPE_YERPB ;  Q8ZJI3, GLPE_YERPE ;  A9R4D5, GLPE_YERPG ;
DR   Q1CCK7, GLPE_YERPN ;  A4TGR3, GLPE_YERPP ;  Q664J2, GLPE_YERPS ;
DR   B1JHY9, GLPE_YERPY ;  P23857, PSPE_ECOLI ;  Q12305, RDL1_YEAST ;
DR   Q08742, RDL2_YEAST ;  Q39129, STR16_ARATH;  P91247, THT1_CAEEL ;
DR   O17730, THT2_CAEEL ;  Q7TWT6, THT2_MYCBO ;  P46700, THT2_MYCLE ;
DR   P96888, THT2_MYCTU ;  Q59570, THT3_MYCTU ;  P59989, THTR1_MYCBO;
DR   Q7TX80, THTR2_MYCBO;  P52197, THTR_AZOVI ;  P00586, THTR_BOVIN ;
DR   P25324, THTR_CHICK ;  P71121, THTR_CORGL ;  P46635, THTR_CRIGR ;
DR   Q9RXT9, THTR_DEIRA ;  D4GYM0, THTR_HALVD ;  Q16762, THTR_HUMAN ;
DR   O26719, THTR_METTH ;  P52196, THTR_MOUSE ;  Q50036, THTR_MYCLE ;
DR   A0R4C9, THTR_MYCS2 ;  O05793, THTR_MYCTU ;  P24329, THTR_RAT   ;
DR   P16385, THTR_SACER ;  P27477, THTR_SYNE7 ;  Q08686, THTR_YEAST ;
DR   P78067, YNJE_ECOLI ;
//
ID   2.8.1.2
DE   3-mercaptopyruvate sulfurtransferase.
CA   3-mercaptopyruvate + cyanide = pyruvate + thiocyanate.
CF   Zinc.
CC   -!- Sulfite, sulfinates, mercaptoethanol and mercaptopyruvate can also
CC       act as acceptors.
PR   PROSITE; PDOC00322;
DR   P58388, THTM_ECO57 ;  P31142, THTM_ECOLI ;  P25325, THTM_HUMAN ;
DR   Q99J99, THTM_MOUSE ;  Q9I452, THTM_PSEAE ;  P97532, THTM_RAT   ;
DR   Q9USJ1, THTM_SCHPO ;
//
ID   2.8.1.3
DE   Thiosulfate--thiol sulfurtransferase.
AN   Glutathione-dependent thiosulfate reductase.
AN   Sulfane reductase.
CA   Thiosulfate + 2 glutathione = sulfite + glutathione disulfide + sulfide.
CC   -!- The primary product is glutathione hydrodisulfide, which reacts with
CC       glutathione to give glutathione disulfide and sulfide.
CC   -!- L-cysteine can also act as acceptor.
//
ID   2.8.1.4
DE   tRNA sulfurtransferase.
CA   L-cysteine + 'activated' tRNA = L-serine + tRNA containing a
CA   thionucleotide.
CC   -!- A group of enzymes transferring sulfur to various nucleotides in a
CC       tRNA chain, producing residues such as 4-thiouridylate.
CC   -!- With some enzymes mercaptopyruvate can act as sulfur donor.
DR   A9NHG7, THII_ACHLI ;  A6VQ53, THII_ACTSZ ;  A0KIY0, THII_AERHH ;
DR   Q9YEW8, THII_AERPE ;  A4SP64, THII_AERS4 ;  B6EIB2, THII_ALISL ;
DR   A6TQ96, THII_ALKMQ ;  A8MHS1, THII_ALKOO ;  B7GGQ4, THII_ANOFW ;
DR   O29382, THII_ARCFU ;  C1DHW2, THII_AZOVD ;  A7Z7N3, THII_BACA2 ;
DR   C3PBB3, THII_BACAA ;  C3L9V4, THII_BACAC ;  A0RJN9, THII_BACAH ;
DR   Q81KU0, THII_BACAN ;  B7JS23, THII_BACC0 ;  Q72Z85, THII_BACC1 ;
DR   B7IK47, THII_BACC2 ;  C1EUZ5, THII_BACC3 ;  B7H703, THII_BACC4 ;
DR   B7HSI4, THII_BACC7 ;  A7GTS8, THII_BACCN ;  B9J151, THII_BACCQ ;
DR   Q817B1, THII_BACCR ;  Q633E8, THII_BACCZ ;  Q9K804, THII_BACHD ;
DR   Q6HCN0, THII_BACHK ;  Q65G52, THII_BACLD ;  A8FG94, THII_BACP2 ;
DR   Q5WEC6, THII_BACSK ;  O34595, THII_BACSU ;  Q493G5, THII_BLOPB ;
DR   C0ZH32, THII_BREBN ;  A8AK31, THII_CITK8 ;  Q97EY4, THII_CLOAB ;
DR   B2UX29, THII_CLOBA ;  Q189U8, THII_CLOD6 ;  B9DZV9, THII_CLOK1 ;
DR   A5N6D9, THII_CLOK5 ;  Q0TQI5, THII_CLOP1 ;  Q8XKI3, THII_CLOPE ;
DR   A9KKT0, THII_CLOPH ;  Q0ST36, THII_CLOPS ;  A3DEB6, THII_CLOTH ;
DR   Q487C7, THII_COLP3 ;  Q83CD9, THII_COXBU ;  B8D4I6, THII_DESK1 ;
DR   A7ZIH7, THII_ECO24 ;  B7UJP6, THII_ECO27 ;  B7MD81, THII_ECO45 ;
DR   B7L657, THII_ECO55 ;  Q8XE74, THII_ECO57 ;  B5Z3S9, THII_ECO5E ;
DR   B7NJ74, THII_ECO7I ;  B7MQD8, THII_ECO81 ;  B7M3R2, THII_ECO8A ;
DR   C4ZTI0, THII_ECOBW ;  B1XF11, THII_ECODH ;  A7ZX76, THII_ECOHS ;
DR   A1A892, THII_ECOK1 ;  Q8FKB7, THII_ECOL6 ;  B1J026, THII_ECOLC ;
DR   P77718, THII_ECOLI ;  B7N8X6, THII_ECOLU ;  B6HZM6, THII_ECOSE ;
DR   B1LJH3, THII_ECOSM ;  Q1RFB7, THII_ECOUT ;  C5BCI2, THII_EDWI9 ;
DR   Q82ZW3, THII_ENTFA ;  Q6D841, THII_ERWCT ;  B2VHS0, THII_ERWT9 ;
DR   B7LMG4, THII_ESCF3 ;  C4Z0P7, THII_EUBE2 ;  C4ZAY9, THII_EUBR3 ;
DR   B0RZV0, THII_FINM2 ;  Q5KW56, THII_GEOKA ;  C5D693, THII_GEOSW ;
DR   A4IRT9, THII_GEOTN ;  Q7VKR6, THII_HAEDU ;  Q4QKG3, THII_HAEI8 ;
DR   A5UC48, THII_HAEIE ;  A5UEV3, THII_HAEIG ;  Q0I3G4, THII_HAES1 ;
DR   B0UUA1, THII_HAES2 ;  B8D0L5, THII_HALOH ;  B0R5A9, THII_HALS3 ;
DR   Q9HQ72, THII_HALSA ;  B5Y0W8, THII_KLEP3 ;  A6T5F6, THII_KLEP7 ;
DR   Q5FKW9, THII_LACAC ;  Q03R12, THII_LACBA ;  Q039U0, THII_LACC3 ;
DR   B3WDV9, THII_LACCB ;  Q04B89, THII_LACDB ;  B2GAZ4, THII_LACF3 ;
DR   Q042N0, THII_LACGA ;  A8YUL5, THII_LACH4 ;  Q74K02, THII_LACJO ;
DR   Q9CII1, THII_LACLA ;  A2RIA6, THII_LACLM ;  Q88UX4, THII_LACPL ;
DR   A5VIU7, THII_LACRD ;  B2G6C3, THII_LACRJ ;  Q1WT71, THII_LACS1 ;
DR   Q38XD3, THII_LACSS ;  Q92BB6, THII_LISIN ;  C1KVN9, THII_LISMC ;
DR   Q71Z75, THII_LISMF ;  B8DHE9, THII_LISMH ;  Q8Y6U0, THII_LISMO ;
DR   A0AJ41, THII_LISW6 ;  B1HX36, THII_LYSSC ;  B9E7C5, THII_MACCJ ;
DR   Q65TP1, THII_MANSM ;  A1U6U9, THII_MARAV ;  Q8TQS4, THII_METAC ;
DR   Q58341, THII_METJA ;  Q8PU39, THII_METMA ;  A5UKU4, THII_METS3 ;
DR   O27720, THII_METTH ;  Q2RM06, THII_MOOTA ;  B3PLZ2, THII_MYCA5 ;
DR   A5IXS0, THII_MYCAP ;  P47612, THII_MYCGE ;  Q8EVH8, THII_MYCPE ;
DR   P75228, THII_MYCPN ;  Q98PK4, THII_MYCPU ;  Q4A5Q7, THII_MYCS5 ;
DR   B2A8M8, THII_NATTJ ;  Q5YY71, THII_NOCFA ;  Q8EPB3, THII_OCEIH ;
DR   P57849, THII_PASMU ;  C6DB40, THII_PECCP ;  Q03EN8, THII_PEDPA ;
DR   Q7N0J9, THII_PHOLL ;  Q6LU02, THII_PHOPR ;  B4EU34, THII_PROMH ;
DR   A6VDN5, THII_PSEA7 ;  B7V3L1, THII_PSEA8 ;  Q02EP8, THII_PSEAB ;
DR   Q9HU66, THII_PSEAE ;  C3K7D0, THII_PSEFS ;  A4XZX0, THII_PSEMY ;
DR   Q3KJG6, THII_PSEPF ;  Q88CY4, THII_PSEPK ;  Q88AM9, THII_PSESM ;
DR   Q4ZLX9, THII_PSEU2 ;  A1SWV3, THII_PSYIN ;  Q8ZT61, THII_PYRAE ;
DR   Q5JCY1, THII_PYRKO ;  Q21NG2, THII_SACD2 ;  B5EXG6, THII_SALA4 ;
DR   A9MM39, THII_SALAR ;  Q57SD9, THII_SALCH ;  B5FKT0, THII_SALDC ;
DR   B5QTH3, THII_SALEP ;  B5R6S6, THII_SALG2 ;  B4T8R6, THII_SALHS ;
DR   B4SWR7, THII_SALNS ;  Q5PFQ4, THII_SALPA ;  A9MX06, THII_SALPB ;
DR   C0Q7V0, THII_SALPC ;  B5BDA7, THII_SALPK ;  B4TMA5, THII_SALSV ;
DR   Q8Z8X1, THII_SALTI ;  P55913, THII_SALTY ;  A8GAP5, THII_SERP5 ;
DR   A1S8C9, THII_SHEAM ;  B8EAU2, THII_SHEB2 ;  A3D2B7, THII_SHEB5 ;
DR   A6WL09, THII_SHEB8 ;  A9KTM0, THII_SHEB9 ;  Q12L31, THII_SHEDO ;
DR   Q07ZD9, THII_SHEFN ;  B0TQ31, THII_SHEHH ;  A3QGN4, THII_SHELP ;
DR   Q8EGR4, THII_SHEON ;  A8H6W6, THII_SHEPA ;  A4Y4X5, THII_SHEPC ;
DR   B8CQH4, THII_SHEPW ;  A0KZA4, THII_SHESA ;  A8FYK5, THII_SHESH ;
DR   Q0HGM0, THII_SHESM ;  Q0HSX1, THII_SHESR ;  A1RLU8, THII_SHESW ;
DR   B1KQY3, THII_SHEWM ;  B2U4M7, THII_SHIB3 ;  Q325H8, THII_SHIBS ;
DR   Q32JI1, THII_SHIDS ;  Q0T7G6, THII_SHIF8 ;  Q83SG1, THII_SHIFL ;
DR   Q3Z4Y6, THII_SHISS ;  Q2NV91, THII_SODGM ;  A7X3E5, THII_STAA1 ;
DR   A6U2I2, THII_STAA2 ;  Q2FG23, THII_STAA3 ;  Q2FXL1, THII_STAA8 ;
DR   A5ITN8, THII_STAA9 ;  Q2YTF0, THII_STAAB ;  Q5HF59, THII_STAAC ;
DR   A6QHP9, THII_STAAE ;  Q931P5, THII_STAAM ;  Q99TE8, THII_STAAN ;
DR   Q6GFZ2, THII_STAAR ;  Q6G8L2, THII_STAAS ;  A8Z2N1, THII_STAAT ;
DR   Q8NW49, THII_STAAW ;  Q5HNJ0, THII_STAEQ ;  Q8CNW7, THII_STAES ;
DR   Q4L756, THII_STAHJ ;  Q49YE8, THII_STAS1 ;  Q3K0E0, THII_STRA1 ;
DR   Q8E4F9, THII_STRA3 ;  Q8DYV1, THII_STRA5 ;  C0M8U4, THII_STRE4 ;
DR   A8AWF4, THII_STRGC ;  Q8DUR1, THII_STRMU ;  Q9A0D8, THII_STRP1 ;
DR   Q04L36, THII_STRP2 ;  P0DF94, THII_STRP3 ;  B5E3Y2, THII_STRP4 ;
DR   Q5XCT0, THII_STRP6 ;  C1C6L4, THII_STRP7 ;  Q8P1G9, THII_STRP8 ;
DR   Q1JCG0, THII_STRPB ;  Q1JMD8, THII_STRPC ;  Q1JHI4, THII_STRPD ;
DR   Q1J7A5, THII_STRPF ;  A2RF72, THII_STRPG ;  B1IB49, THII_STRPI ;
DR   B8ZNS6, THII_STRPJ ;  Q48U81, THII_STRPM ;  Q97RE1, THII_STRPN ;
DR   P0DF95, THII_STRPQ ;  B2IP11, THII_STRPS ;  B5XKV0, THII_STRPZ ;
DR   Q8DQ92, THII_STRR6 ;  A4W0P5, THII_STRS2 ;  C0MGK8, THII_STRS7 ;
DR   A3CMR7, THII_STRSV ;  A4VUF4, THII_STRSY ;  B9DU51, THII_STRU0 ;
DR   C1CDN0, THII_STRZJ ;  C1CJW9, THII_STRZP ;  C1CS14, THII_STRZT ;
DR   Q4J6G3, THII_SULAC ;  C3MZC6, THII_SULIA ;  C4KIK6, THII_SULIK ;
DR   C3MR91, THII_SULIL ;  C3MXI0, THII_SULIM ;  C3NG28, THII_SULIN ;
DR   C3N7E8, THII_SULIY ;  Q980G6, THII_SULSO ;  Q96YE5, THII_SULTO ;
DR   Q9HKT9, THII_THEAC ;  Q9X220, THII_THEMA ;  B0K8J2, THII_THEP3 ;
DR   B0K3I5, THII_THEPX ;  Q72HP1, THII_THET2 ;  Q5SHD4, THII_THET8 ;
DR   Q8R9F0, THII_THETN ;  Q97AK6, THII_THEVO ;  C4LAC1, THII_TOLAT ;
DR   O83570, THII_TREPA ;  B2S3F1, THII_TREPS ;  B1AJ58, THII_UREP2 ;
DR   Q9PQ71, THII_UREPA ;  B5ZBR5, THII_UREU1 ;  Q9KTK8, THII_VIBCH ;
DR   Q5E6Y5, THII_VIBF1 ;  B5FBH1, THII_VIBFM ;  A7MYC5, THII_VIBHB ;
DR   Q87RT6, THII_VIBPA ;  B7VJ96, THII_VIBSL ;  Q8DFA8, THII_VIBVU ;
DR   Q7MN44, THII_VIBVY ;  A1JNR2, THII_YERE8 ;  A7FLE0, THII_YERP3 ;
DR   Q1C4J3, THII_YERPA ;  B2K6U1, THII_YERPB ;  Q8ZC49, THII_YERPE ;
DR   A9QZR9, THII_YERPG ;  Q1CL83, THII_YERPN ;  A4TPF8, THII_YERPP ;
DR   Q66DV0, THII_YERPS ;  B1JID5, THII_YERPY ;
//
ID   2.8.1.5
DE   Thiosulfate--dithiol sulfurtransferase.
AN   Thiosulfate reductase.
CA   Thiosulfate + dithioerythritol = sulfite + 4,5-cis-dihydroxy-1,2-
CA   dithiacyclohexane + sulfide.
CC   -!- The enzyme from Chlorella shows very little activity toward
CC       monothiols such as glutathione and cysteine (cf. EC 2.8.1.3).
CC   -!- The enzyme probably transfers the sulfur atom onto one thiol group to
CC       form -S-S(-), and sulfide is spontaneously expelled from this by
CC       reaction with the other thiol group.
CC   -!- May be identical with EC 2.8.1.1.
//
ID   2.8.1.6
DE   Biotin synthase.
CA   Dethiobiotin + sulfur + 2 S-adenosyl-L-methionine = biotin +
CA   2 L-methionine + 2 5'-deoxyadenosine.
CF   Iron-sulfur.
CC   -!- The enzyme binds a [4Fe-4S] and a [2Fe-2S] cluster.
CC   -!- In every reaction cycle, the enzyme consumes two molecules of AdoMet,
CC       each producing 5'-deoxyadenosine and a putative dethiobiotinyl carbon
CC       radical.
CC   -!- Reaction with another equivalent of AdoMet results in abstraction of
CC       the C6 methylene pro-(S) hydrogen atom from 9-mercaptodethiobiotin,
CC       and the resulting carbon radical is quenched via formation of an
CC       intramolecular C-S bond, thus closing the biotin thiophane ring.
CC   -!- The sulfur donor (S) is believed to be the [2Fe-2S] cluster, which is
CC       sacrificed in the process, so that in vitro the reaction is a single
CC       turnover.
CC   -!- In vivo, the [2Fe-2S] cluster can be reassembled by the Isc or Suf
CC       iron-sulfur cluster assembly systems, to allow further catalysis.
DR   E1WTS4, BIOAB_BACF6;  Q5LEY1, BIOAB_BACFN;  Q64VX4, BIOAB_BACFR;
DR   E6SRG2, BIOAB_BACT6;  Q8A7T2, BIOAB_BACTN;  Q6NKC7, BIOB1_CORDI;
DR   Q2J6H8, BIOB1_FRASC;  A1B1Z0, BIOB1_PARDP;  Q12F39, BIOB1_POLSJ;
DR   Q6NHL3, BIOB2_CORDI;  Q2J5A7, BIOB2_FRASC;  A1B656, BIOB2_PARDP;
DR   Q12D73, BIOB2_POLSJ;  B0CC69, BIOB_ACAM1 ;  A1TQ53, BIOB_ACIAC ;
DR   Q6FAP9, BIOB_ACIAD ;  B7H3S4, BIOB_ACIB3 ;  B7I4I4, BIOB_ACIB5 ;
DR   B2HYX9, BIOB_ACIBC ;  B0VR41, BIOB_ACIBS ;  A3M4U4, BIOB_ACIBT ;
DR   B0VCA8, BIOB_ACIBY ;  A0LTP8, BIOB_ACIC1 ;  Q93GG2, BIOB_ACICA ;
DR   A5FZN9, BIOB_ACICJ ;  B9MJH4, BIOB_ACIET ;  B7J403, BIOB_ACIF2 ;
DR   B5ELR8, BIOB_ACIF5 ;  A1W7J6, BIOB_ACISJ ;  A3MYI9, BIOB_ACTP2 ;
DR   B3GZV8, BIOB_ACTP7 ;  B0BS22, BIOB_ACTPJ ;  A6VNF1, BIOB_ACTSZ ;
DR   A0KIC6, BIOB_AERHH ;  A4SPR7, BIOB_AERS4 ;  B9J9I5, BIOB_AGRRK ;
DR   A9CFX5, BIOB_AGRT5 ;  B9JYY6, BIOB_AGRVS ;  B2UNW0, BIOB_AKKM8 ;
DR   Q0VMD0, BIOB_ALCBS ;  Q0A5W1, BIOB_ALHEH ;  B6ESC7, BIOB_ALISL ;
DR   A6TT61, BIOB_ALKMQ ;  B4S0P9, BIOB_ALTMD ;  B8J638, BIOB_ANAD2 ;
DR   Q2IF61, BIOB_ANADE ;  A7HG97, BIOB_ANADF ;  B9KGM2, BIOB_ANAMF ;
DR   Q5PA14, BIOB_ANAMM ;  Q2GLB4, BIOB_ANAPZ ;  B4UCB2, BIOB_ANASK ;
DR   B9MP50, BIOB_ANATD ;  Q3M4U9, BIOB_ANAVT ;  B7GKT8, BIOB_ANOFW ;
DR   O67104, BIOB_AQUAE ;  P54967, BIOB_ARATH ;  A8EWX7, BIOB_ARCB4 ;
DR   Q5P7M6, BIOB_AROAE ;  A1R3R7, BIOB_ARTAT ;  B8HDH4, BIOB_ARTCA ;
DR   A0JTA3, BIOB_ARTS2 ;  A8IJU8, BIOB_AZOC5 ;  A1K9C8, BIOB_AZOSB ;
DR   A7Z5B2, BIOB_BACA2 ;  A0RIB6, BIOB_BACAH ;  Q70JZ1, BIOB_BACAM ;
DR   Q81MB3, BIOB_BACAN ;  B7JLW9, BIOB_BACC0 ;  Q731I2, BIOB_BACC1 ;
DR   B7IWM8, BIOB_BACC2 ;  B7HAY7, BIOB_BACC4 ;  B7HNN1, BIOB_BACC7 ;
DR   A7GSD8, BIOB_BACCN ;  B9IWX7, BIOB_BACCQ ;  Q818X3, BIOB_BACCR ;
DR   Q635G7, BIOB_BACCZ ;  Q9KC26, BIOB_BACHD ;  Q6HE51, BIOB_BACHK ;
DR   Q65MK9, BIOB_BACLD ;  Q8KZM7, BIOB_BACNA ;  A8FGR8, BIOB_BACP2 ;
DR   P53557, BIOB_BACSU ;  A9VG53, BIOB_BACWK ;  Q1LTL8, BIOB_BAUCH ;
DR   B2IEZ6, BIOB_BEII9 ;  Q2KWF1, BIOB_BORA1 ;  Q7WMQ3, BIOB_BORBR ;
DR   Q7WB85, BIOB_BORPA ;  A9I023, BIOB_BORPD ;  Q7VVF1, BIOB_BORPE ;
DR   C0QVM0, BIOB_BRAHW ;  Q9AMS7, BIOB_BRAJA ;  A5EFG5, BIOB_BRASB ;
DR   A4YQS3, BIOB_BRASO ;  B2SBF0, BIOB_BRUA1 ;  Q2YKB8, BIOB_BRUA2 ;
DR   Q577P8, BIOB_BRUAB ;  A9MBD6, BIOB_BRUC2 ;  C0RL26, BIOB_BRUMB ;
DR   Q8YBW1, BIOB_BRUME ;  A5VUG1, BIOB_BRUO2 ;  A9WYH2, BIOB_BRUSI ;
DR   Q8FWG3, BIOB_BRUSU ;  B8D983, BIOB_BUCA5 ;  P57378, BIOB_BUCAI ;
DR   Q8K9P1, BIOB_BUCAP ;  B8D7I5, BIOB_BUCAT ;  Q89AK5, BIOB_BUCBP ;
DR   B1YNS2, BIOB_BURA4 ;  Q1BT34, BIOB_BURCA ;  B1JZE1, BIOB_BURCC ;
DR   A0KB05, BIOB_BURCH ;  B4E9L4, BIOB_BURCJ ;  Q0BBD4, BIOB_BURCM ;
DR   A9AE44, BIOB_BURM1 ;  A3MNG1, BIOB_BURM7 ;  A2S7R3, BIOB_BURM9 ;
DR   Q62MW9, BIOB_BURMA ;  A1V817, BIOB_BURMS ;  A3NQS1, BIOB_BURP0 ;
DR   Q3JWR8, BIOB_BURP1 ;  A3N520, BIOB_BURP6 ;  B2JKH4, BIOB_BURP8 ;
DR   B2SWS5, BIOB_BURPP ;  Q63Y25, BIOB_BURPS ;  Q39CE4, BIOB_BURS3 ;
DR   Q2T1Q4, BIOB_BURTA ;  A4JIB7, BIOB_BURVG ;  Q146K5, BIOB_BURXL ;
DR   A4XGB8, BIOB_CALS8 ;  A7ZFR4, BIOB_CAMC1 ;  A7H0I4, BIOB_CAMC5 ;
DR   A0RME8, BIOB_CAMFF ;  A7I1A0, BIOB_CAMHC ;  A8FNZ2, BIOB_CAMJ8 ;
DR   A7H632, BIOB_CAMJD ;  Q0P7U6, BIOB_CAMJE ;  A1W1T3, BIOB_CAMJJ ;
DR   Q5HSB2, BIOB_CAMJR ;  B9KEN8, BIOB_CAMLR ;  Q3ADP5, BIOB_CARHZ ;
DR   B8H640, BIOB_CAUCN ;  Q9A2N5, BIOB_CAUCR ;  B0T1Y4, BIOB_CAUSK ;
DR   B3PI87, BIOB_CELJU ;  A0RW96, BIOB_CENSY ;  Q5L5F9, BIOB_CHLAB ;
DR   Q3ANX4, BIOB_CHLCH ;  Q255G8, BIOB_CHLFF ;  B3EI42, BIOB_CHLL2 ;
DR   B3QLR7, BIOB_CHLP8 ;  B3EPW2, BIOB_CHLPB ;  A1BCQ5, BIOB_CHLPD ;
DR   Q9Z6L5, BIOB_CHLPN ;  Q8KGB6, BIOB_CHLTE ;  Q1QYD5, BIOB_CHRSD ;
DR   Q7NPW1, BIOB_CHRVO ;  P12997, BIOB_CITFR ;  A8AJ12, BIOB_CITK8 ;
DR   Q97MI6, BIOB_CLOAB ;  A7FVS6, BIOB_CLOB1 ;  A6LUQ4, BIOB_CLOB8 ;
DR   B2V167, BIOB_CLOBA ;  B2TL73, BIOB_CLOBB ;  A5I427, BIOB_CLOBH ;
DR   B1IHH9, BIOB_CLOBK ;  A7GFJ9, BIOB_CLOBL ;  B1KW08, BIOB_CLOBM ;
DR   Q18D35, BIOB_CLOD6 ;  B9E2A2, BIOB_CLOK1 ;  A0PYU9, BIOB_CLONN ;
DR   Q0TQ59, BIOB_CLOP1 ;  Q8XK59, BIOB_CLOPE ;  Q899M1, BIOB_CLOTE ;
DR   A3DBD3, BIOB_CLOTH ;  Q481G0, BIOB_COLP3 ;  Q8FUD1, BIOB_COREF ;
DR   A4QA10, BIOB_CORGB ;  P46396, BIOB_CORGL ;  Q4JWG3, BIOB_CORJK ;
DR   B1VF77, BIOB_CORU7 ;  B6J725, BIOB_COXB1 ;  B6J074, BIOB_COXB2 ;
DR   A9KG71, BIOB_COXBN ;  A9NCS0, BIOB_COXBR ;  Q83CU5, BIOB_COXBU ;
DR   Q0KF86, BIOB_CUPNH ;  Q477A1, BIOB_CUPPJ ;  B2AGA0, BIOB_CUPTR ;
DR   B1WTI3, BIOB_CYAA5 ;  B8HPP0, BIOB_CYAP4 ;  B7KFJ9, BIOB_CYAP7 ;
DR   B7K1U3, BIOB_CYAP8 ;  Q11S94, BIOB_CYTH3 ;  Q47IF6, BIOB_DECAR ;
DR   A9C2R2, BIOB_DELAS ;  B8FHQ1, BIOB_DESAA ;  C6C0T2, BIOB_DESAD ;
DR   B1I4G4, BIOB_DESAP ;  B8J0C6, BIOB_DESDA ;  Q30XZ5, BIOB_DESDG ;
DR   A8ZUS9, BIOB_DESOH ;  Q6AK48, BIOB_DESPS ;  A4J1M3, BIOB_DESRM ;
DR   Q728P5, BIOB_DESVH ;  B8DPP9, BIOB_DESVM ;  A1VB97, BIOB_DESVV ;
DR   A7ZJI4, BIOB_ECO24 ;  B7ULX2, BIOB_ECO27 ;  B7MGN3, BIOB_ECO45 ;
DR   B7LC57, BIOB_ECO55 ;  Q8X825, BIOB_ECO57 ;  B5YRL4, BIOB_ECO5E ;
DR   B7NNK5, BIOB_ECO7I ;  B7MQM8, BIOB_ECO81 ;  B7M747, BIOB_ECO8A ;
DR   B1X7A5, BIOB_ECODH ;  A7ZY31, BIOB_ECOHS ;  A1A917, BIOB_ECOK1 ;
DR   Q0TJS3, BIOB_ECOL5 ;  Q8FJQ3, BIOB_ECOL6 ;  B1IXJ3, BIOB_ECOLC ;
DR   P12996, BIOB_ECOLI ;  B7NA74, BIOB_ECOLU ;  B6I7S9, BIOB_ECOSE ;
DR   B1LM66, BIOB_ECOSM ;  Q1REF5, BIOB_ECOUT ;  Q3YRG6, BIOB_EHRCJ ;
DR   Q2GHB1, BIOB_EHRCR ;  Q5FFY2, BIOB_EHRRG ;  Q5HAN0, BIOB_EHRRW ;
DR   A4W8B7, BIOB_ENT38 ;  A7MJ03, BIOB_ENTS8 ;  Q6D3B9, BIOB_ERWCT ;
DR   B2VBT9, BIOB_ERWT9 ;  Q2NB65, BIOB_ERYLH ;  B7LJY8, BIOB_ESCF3 ;
DR   Q47862, BIOB_ESCVU ;  A5FLT1, BIOB_FLAJ1 ;  A6GW77, BIOB_FLAPJ ;
DR   Q0RD46, BIOB_FRAAA ;  B0U0S3, BIOB_FRAP2 ;  A8L2N0, BIOB_FRASN ;
DR   Q14HR4, BIOB_FRAT1 ;  A7NCW7, BIOB_FRATF ;  Q2A2V9, BIOB_FRATH ;
DR   B2SGE3, BIOB_FRATM ;  A0Q638, BIOB_FRATN ;  Q0BLD5, BIOB_FRATO ;
DR   Q5NGB2, BIOB_FRATT ;  A4IXP5, BIOB_FRATW ;  Q8REU0, BIOB_FUSNN ;
DR   B5ECN1, BIOB_GEOBB ;  Q5KZN1, BIOB_GEOKA ;  B3E599, BIOB_GEOLS ;
DR   Q39VB0, BIOB_GEOMG ;  B9M305, BIOB_GEOSF ;  Q74CT7, BIOB_GEOSL ;
DR   A4IN84, BIOB_GEOTN ;  A5G3Q7, BIOB_GEOUR ;  Q7NDA8, BIOB_GLOVI ;
DR   A9HRF2, BIOB_GLUDA ;  Q5FPC9, BIOB_GLUOX ;  Q0BUV5, BIOB_GRABC ;
DR   A0M7A9, BIOB_GRAFK ;  Q7VMH0, BIOB_HAEDU ;  Q4QLQ0, BIOB_HAEI8 ;
DR   A5UD65, BIOB_HAEIE ;  A5UIF3, BIOB_HAEIG ;  P44987, BIOB_HAEIN ;
DR   B8F6C9, BIOB_HAEPS ;  Q0I355, BIOB_HAES1 ;  B0UUK6, BIOB_HAES2 ;
DR   Q2SBD4, BIOB_HAHCH ;  A1WVM7, BIOB_HALHL ;  Q17VA0, BIOB_HELAH ;
DR   Q7VFE6, BIOB_HELHP ;  B0TE53, BIOB_HELMI ;  B6JNP9, BIOB_HELP2 ;
DR   B5Z928, BIOB_HELPG ;  Q1CRM5, BIOB_HELPH ;  Q9ZJK8, BIOB_HELPJ ;
DR   B2UVE8, BIOB_HELPS ;  O25956, BIOB_HELPY ;  A4G1F1, BIOB_HERAR ;
DR   B4U973, BIOB_HYDS0 ;  Q0C661, BIOB_HYPNA ;  Q5QZ16, BIOB_IDILO ;
DR   A6SU66, BIOB_JANMA ;  B5XZ75, BIOB_KLEP3 ;  A6T6L5, BIOB_KLEP7 ;
DR   B2GLQ7, BIOB_KOCRD ;  Q1MRA1, BIOB_LAWIP ;  Q5X592, BIOB_LEGPA ;
DR   A5IBW2, BIOB_LEGPC ;  Q5ZVG8, BIOB_LEGPH ;  Q5WW97, BIOB_LEGPL ;
DR   B0SDC5, BIOB_LEPBA ;  Q04RS9, BIOB_LEPBJ ;  Q051U2, BIOB_LEPBL ;
DR   B0SLQ3, BIOB_LEPBP ;  B1Y502, BIOB_LEPCP ;  Q72RG8, BIOB_LEPIC ;
DR   Q8F498, BIOB_LEPIN ;  B1HRT3, BIOB_LYSSC ;  P19206, BIOB_LYSSH ;
DR   B9EA22, BIOB_MACCJ ;  Q2W3L4, BIOB_MAGSA ;  A0L3M0, BIOB_MAGSM ;
DR   Q65SD0, BIOB_MANSM ;  A1U4B2, BIOB_MARAV ;  Q0ATN3, BIOB_MARMM ;
DR   A6W0Y1, BIOB_MARMS ;  A6UTF3, BIOB_META3 ;  B7KN34, BIOB_METC4 ;
DR   Q609V2, BIOB_METCA ;  A9W8M8, BIOB_METEP ;  Q1GZA6, BIOB_METFK ;
DR   B3DV36, BIOB_METI4 ;  Q58692, BIOB_METJA ;  A4FWU0, BIOB_METM5 ;
DR   A9AA75, BIOB_METM6 ;  A6VGH7, BIOB_METM7 ;  Q6LXV8, BIOB_METMP ;
DR   B8IU36, BIOB_METNO ;  B1ZFX7, BIOB_METPB ;  A2SGQ6, BIOB_METPP ;
DR   B1LV19, BIOB_METRJ ;  B0U811, BIOB_METS4 ;  B8EMZ5, BIOB_METSB ;
DR   P94966, BIOB_METSK ;  A6UPN7, BIOB_METVS ;  B0JFP4, BIOB_MICAN ;
DR   A0QHJ1, BIOB_MYCA1 ;  B1MBZ3, BIOB_MYCA9 ;  P0A507, BIOB_MYCBO ;
DR   A1KJ05, BIOB_MYCBP ;  A4T9L9, BIOB_MYCGI ;  B8ZR86, BIOB_MYCLB ;
DR   P46715, BIOB_MYCLE ;  B2HQ93, BIOB_MYCMM ;  Q740Q9, BIOB_MYCPA ;
DR   A0QX70, BIOB_MYCS2 ;  A3Q142, BIOB_MYCSJ ;  A1UHL9, BIOB_MYCSK ;
DR   Q1B7F4, BIOB_MYCSS ;  A5U2U5, BIOB_MYCTA ;  A5WMR0, BIOB_MYCTF ;
DR   P0A506, BIOB_MYCTU ;  A0PP05, BIOB_MYCUA ;  A1T8V0, BIOB_MYCVP ;
DR   Q1DCV9, BIOB_MYXXD ;  Q3INU3, BIOB_NATPD ;  B9L7E1, BIOB_NAUPA ;
DR   Q5F8G2, BIOB_NEIG1 ;  B4RLI6, BIOB_NEIG2 ;  A9LZ69, BIOB_NEIM0 ;
DR   A1IRY3, BIOB_NEIMA ;  Q9JRW7, BIOB_NEIMB ;  A1KU01, BIOB_NEIMF ;
DR   Q2GDF4, BIOB_NEOSM ;  Q0AE72, BIOB_NITEC ;  Q82SL7, BIOB_NITEU ;
DR   Q1QRH1, BIOB_NITHX ;  A9A5K6, BIOB_NITMS ;  Q2Y9Y9, BIOB_NITMU ;
DR   Q3J9D5, BIOB_NITOC ;  A6Q5K0, BIOB_NITSB ;  Q3SW30, BIOB_NITWN ;
DR   Q5YYR3, BIOB_NOCFA ;  A1SM80, BIOB_NOCSJ ;  B2J914, BIOB_NOSP7 ;
DR   Q8YVQ3, BIOB_NOSS1 ;  Q2GAF7, BIOB_NOVAD ;  A6X2S8, BIOB_OCHA4 ;
DR   B6JDD7, BIOB_OLICO ;  A6LD84, BIOB_PARD8 ;  A7HP26, BIOB_PARL1 ;
DR   Q9CNP8, BIOB_PASMU ;  Q3A4K3, BIOB_PELCD ;  Q3B169, BIOB_PELLD ;
DR   B4SGZ7, BIOB_PELPB ;  A1AN77, BIOB_PELPD ;  A5D4Y6, BIOB_PELTS ;
DR   C0QR28, BIOB_PERMH ;  B4RBP5, BIOB_PHEZH ;  Q7N6Q7, BIOB_PHOLL ;
DR   Q6LPR2, BIOB_PHOPR ;  A1VUJ4, BIOB_POLNA ;  A4SV63, BIOB_POLSQ ;
DR   B2RH08, BIOB_PORG3 ;  Q7MT97, BIOB_PORGI ;  B4S690, BIOB_PROA2 ;
DR   Q6A7V7, BIOB_PROAC ;  A3PDJ8, BIOB_PROM0 ;  A2C3I4, BIOB_PROM1 ;
DR   A8G5G3, BIOB_PROM2 ;  A2C8D5, BIOB_PROM3 ;  A9BB12, BIOB_PROM4 ;
DR   A2BX80, BIOB_PROM5 ;  Q31AD2, BIOB_PROM9 ;  Q7VBJ0, BIOB_PROMA ;
DR   B4ESU3, BIOB_PROMH ;  Q7V6T8, BIOB_PROMM ;  Q7V101, BIOB_PROMP ;
DR   A2BRS2, BIOB_PROMS ;  Q46K32, BIOB_PROMT ;  A4SGW2, BIOB_PROVI ;
DR   Q48CS1, BIOB_PSE14 ;  Q15SR5, BIOB_PSEA6 ;  A6UYW0, BIOB_PSEA7 ;
DR   B7V485, BIOB_PSEA8 ;  Q02TR6, BIOB_PSEAB ;  Q9I618, BIOB_PSEAE ;
DR   Q1I3N6, BIOB_PSEE4 ;  Q4K4T2, BIOB_PSEF5 ;  Q3IGS6, BIOB_PSEHT ;
DR   A4XZR9, BIOB_PSEMY ;  A5VXF1, BIOB_PSEP1 ;  Q3K5P1, BIOB_PSEPF ;
DR   B0KJ53, BIOB_PSEPG ;  Q88QX2, BIOB_PSEPK ;  B1JE55, BIOB_PSEPW ;
DR   Q88A98, BIOB_PSESM ;  Q4ZMA8, BIOB_PSEU2 ;  A4VR88, BIOB_PSEU5 ;
DR   Q4FQJ9, BIOB_PSYA2 ;  Q1Q8S6, BIOB_PSYCK ;  A1SW31, BIOB_PSYIN ;
DR   A5WHI6, BIOB_PSYWF ;  Q1LS73, BIOB_RALME ;  B2UDA1, BIOB_RALPJ ;
DR   Q8Y2R9, BIOB_RALSO ;  A9WL37, BIOB_RENSM ;  Q7UF84, BIOB_RHOBA ;
DR   Q21W43, BIOB_RHOFD ;  Q2IUT3, BIOB_RHOP2 ;  Q07PI4, BIOB_RHOP5 ;
DR   Q6N859, BIOB_RHOPA ;  Q212A8, BIOB_RHOPB ;  Q138Z3, BIOB_RHOPS ;
DR   B3QCX3, BIOB_RHOPT ;  A3PH74, BIOB_RHOS1 ;  Q3J561, BIOB_RHOS4 ;
DR   B9KM96, BIOB_RHOSK ;  Q0SHW6, BIOB_RHOSR ;  Q4UM45, BIOB_RICFE ;
DR   A1AWE7, BIOB_RUTMC ;  Q21FY3, BIOB_SACD2 ;  A4FIS6, BIOB_SACEN ;
DR   B5F072, BIOB_SALA4 ;  A8LUR1, BIOB_SALAI ;  A9MJE6, BIOB_SALAR ;
DR   Q57RG3, BIOB_SALCH ;  B5FP61, BIOB_SALDC ;  B5QX65, BIOB_SALEP ;
DR   B5R761, BIOB_SALG2 ;  B4TC48, BIOB_SALHS ;  B4SZJ7, BIOB_SALNS ;
DR   Q5PG48, BIOB_SALPA ;  A9MTI8, BIOB_SALPB ;  C0PWY2, BIOB_SALPC ;
DR   B5BC31, BIOB_SALPK ;  Q2S4I8, BIOB_SALRD ;  B4TQT9, BIOB_SALSV ;
DR   Q8Z893, BIOB_SALTI ;  A4X585, BIOB_SALTO ;  P12678, BIOB_SALTY ;
DR   O59778, BIOB_SCHPO ;  P36569, BIOB_SERMA ;  A8GBC5, BIOB_SERP5 ;
DR   A1S5I9, BIOB_SHEAM ;  B8EAJ2, BIOB_SHEB2 ;  A3D3F2, BIOB_SHEB5 ;
DR   A6WM55, BIOB_SHEB8 ;  A9KY60, BIOB_SHEB9 ;  Q12NN4, BIOB_SHEDO ;
DR   Q084I8, BIOB_SHEFN ;  B0TJN8, BIOB_SHEHH ;  A3QDN8, BIOB_SHELP ;
DR   Q8EDK6, BIOB_SHEON ;  A8H3I7, BIOB_SHEPA ;  A4Y7Y3, BIOB_SHEPC ;
DR   B8CQY2, BIOB_SHEPW ;  A0KY79, BIOB_SHESA ;  A8FX10, BIOB_SHESH ;
DR   Q0HHN7, BIOB_SHESM ;  Q0HTY9, BIOB_SHESR ;  A1RIK5, BIOB_SHESW ;
DR   B1KPJ7, BIOB_SHEWM ;  B2TVF5, BIOB_SHIB3 ;  Q324B7, BIOB_SHIBS ;
DR   Q32I44, BIOB_SHIDS ;  Q0T6I5, BIOB_SHIF8 ;  Q83S46, BIOB_SHIFL ;
DR   Q3Z409, BIOB_SHISS ;  Q5LN74, BIOB_SILPO ;  Q2NUJ7, BIOB_SODGM ;
DR   A9EXH2, BIOB_SORC5 ;  Q1GTT5, BIOB_SPHAL ;  A5VAC6, BIOB_SPHWW ;
DR   A7X669, BIOB_STAA1 ;  A6U4F5, BIOB_STAA2 ;  Q2FE72, BIOB_STAA3 ;
DR   Q2FVJ7, BIOB_STAA8 ;  A5IVK5, BIOB_STAA9 ;  Q2YVY6, BIOB_STAAB ;
DR   Q5HDC9, BIOB_STAAC ;  A6QJR4, BIOB_STAAE ;  Q99RK7, BIOB_STAAM ;
DR   Q7A3R9, BIOB_STAAN ;  Q6GE08, BIOB_STAAR ;  Q6G6P6, BIOB_STAAS ;
DR   A8YYH5, BIOB_STAAT ;  Q7A018, BIOB_STAAW ;  B9DKN5, BIOB_STACT ;
DR   Q5HKJ7, BIOB_STAEQ ;  Q8CQB3, BIOB_STAES ;  Q4L9U7, BIOB_STAHJ ;
DR   Q3K2Q5, BIOB_STRA1 ;  Q8E6Q1, BIOB_STRA3 ;  Q8E197, BIOB_STRA5 ;
DR   Q826T2, BIOB_STRAW ;  Q9FCC3, BIOB_STRCO ;  B1W5F4, BIOB_STRGG ;
DR   B4SM81, BIOB_STRM5 ;  B2FLM4, BIOB_STRMK ;  Q30U81, BIOB_SULDN ;
DR   A6Q6D8, BIOB_SULNB ;  B2V8G9, BIOB_SULSY ;  Q2LY09, BIOB_SYNAS ;
DR   Q31R68, BIOB_SYNE7 ;  A0LJA8, BIOB_SYNFM ;  Q2JRI4, BIOB_SYNJA ;
DR   B1XNE1, BIOB_SYNP2 ;  Q5N332, BIOB_SYNP6 ;  A5GLZ1, BIOB_SYNPW ;
DR   Q7U7P8, BIOB_SYNPX ;  A5GS37, BIOB_SYNR3 ;  Q0IBC8, BIOB_SYNS3 ;
DR   Q3AX82, BIOB_SYNS9 ;  Q3AJ51, BIOB_SYNSC ;  P73538, BIOB_SYNY3 ;
DR   Q8DL38, BIOB_THEEB ;  B9KBR9, BIOB_THENN ;  A5IK57, BIOB_THEP1 ;
DR   Q72L21, BIOB_THET2 ;  Q5SKN6, BIOB_THET8 ;  B5YK85, BIOB_THEYD ;
DR   Q31E55, BIOB_THICR ;  Q3SLY0, BIOB_THIDA ;  B8GTH4, BIOB_THISH ;
DR   Q10YQ3, BIOB_TRIEI ;  B1GYW9, BIOB_UNCTG ;  A5CWW0, BIOB_VESOH ;
DR   A5F2H3, BIOB_VIBC3 ;  Q9KSZ4, BIOB_VIBCH ;  B1WN69, BIOB_VIBF1 ;
DR   B5EUQ0, BIOB_VIBFM ;  A7MX36, BIOB_VIBHB ;  Q87QN6, BIOB_VIBPA ;
DR   B7VH16, BIOB_VIBSL ;  Q8D8M9, BIOB_VIBVU ;  Q7MLV0, BIOB_VIBVY ;
DR   Q8D2A1, BIOB_WIGBR ;  Q7M8P7, BIOB_WOLSU ;  Q8PQD7, BIOB_XANAC ;
DR   Q3BYM9, BIOB_XANC5 ;  Q4UZN8, BIOB_XANC8 ;  B0RMR2, BIOB_XANCB ;
DR   Q8PDF0, BIOB_XANCP ;  Q2P8F3, BIOB_XANOM ;  B2SS67, BIOB_XANOP ;
DR   Q5H5R1, BIOB_XANOR ;  A7IEC3, BIOB_XANP2 ;  B2I672, BIOB_XYLF2 ;
DR   Q9PH80, BIOB_XYLFA ;  B0U2A0, BIOB_XYLFM ;  Q87F85, BIOB_XYLFT ;
DR   P32451, BIOB_YEAST ;  A1JS69, BIOB_YERE8 ;  A7FKM9, BIOB_YERP3 ;
DR   Q1C947, BIOB_YERPA ;  B2K8T0, BIOB_YERPB ;  Q7CH65, BIOB_YERPE ;
DR   A9R3C8, BIOB_YERPG ;  Q1CFQ3, BIOB_YERPN ;  A4TNQ6, BIOB_YERPP ;
DR   Q66D67, BIOB_YERPS ;  B1JSS4, BIOB_YERPY ;  Q5NRD6, BIOB_ZYMMO ;
//
ID   2.8.1.7
DE   Cysteine desulfurase.
AN   Cysteine desulfurylase.
CA   L-cysteine + [enzyme]-cysteine = L-alanine + [enzyme]-S-sulfanylcysteine.
CF   Pyridoxal 5'-phosphate.
CC   -!- The reaction shown is the first part of a catalytic reaction, which
CC       is completed by passing on its extra sulfur to other acceptors.
CC   -!- In Azotobacter vinelandii, this sulfur provides the inorganic sulfide
CC       required for nitrogenous metallocluster formation.
CC   -!- The enzyme is involved in the biosynthesis of iron-sulfur clusters,
CC       thio-nucleosides in tRNA, thiamine, biotin, lipoate and pyranopterin
CC       (molybdopterin) and functions by mobilizing sulfur.
DR   O32975, CSD1_MYCLE ;  Q49690, CSD2_MYCLE ;  Q9YAB6, CSD_AERPE  ;
DR   Q9K7A0, CSD_BACHD  ;  O32164, CSD_BACSU  ;  O51111, CSD_BORBU  ;
DR   Q9PLP0, CSD_CHLMU  ;  Q9Z7L5, CSD_CHLPN  ;  O84693, CSD_CHLTR  ;
DR   Q57476, CSD_HAEIN  ;  Q9HMM6, CSD_HALSA  ;  O27442, CSD_METTH  ;
DR   P63517, CSD_MYCBO  ;  Q49420, CSD_MYCGE  ;  Q9KII6, CSD_MYCPA  ;
DR   P75298, CSD_MYCPN  ;  P63516, CSD_MYCTU  ;  P57989, CSD_PASMU  ;
DR   Q9HXX3, CSD_PSEAE  ;  Q9Z408, CSD_PSEPK  ;  Q9V242, CSD_PYRAB  ;
DR   Q5HHH0, CSD_STAAC  ;  P63518, CSD_STAAM  ;  P99177, CSD_STAAN  ;
DR   Q6GIH2, CSD_STAAR  ;  Q6GB11, CSD_STAAS  ;  Q8NXH0, CSD_STAAW  ;
DR   Q5HQQ0, CSD_STAEQ  ;  Q8CTA4, CSD_STAES  ;  Q9XAD5, CSD_STRCO  ;
DR   Q55793, CSD_SYNY3  ;  Q9X191, CSD_THEMA  ;  O83623, CSD_TREPA  ;
DR   Q9PQ36, CSD_UREPA  ;  Q9KPQ7, CSD_VIBCH  ;  Q9PDA6, CSD_XYLFA  ;
DR   Q87DJ2, CSD_XYLFT  ;  O30052, ISCS1_ARCFU;  O34599, ISCS1_BACSU;
DR   O29689, ISCS2_ARCFU;  O34874, ISCS2_BACSU;  B7H3H0, ISCS_ACIB3 ;
DR   B7I5Q3, ISCS_ACIB5 ;  B2HZI5, ISCS_ACIBC ;  B0VNW2, ISCS_ACIBS ;
DR   B0VD51, ISCS_ACIBY ;  A6VMN7, ISCS_ACTSZ ;  A0KJ32, ISCS_AERHH ;
DR   A4SP14, ISCS_AERS4 ;  B8JC53, ISCS_ANAD2 ;  Q2INI7, ISCS_ANADE ;
DR   A7H804, ISCS_ANADF ;  B4UCP2, ISCS_ANASK ;  C1DE68, ISCS_AZOVD ;
DR   O31269, ISCS_AZOVI ;  Q9KDJ6, ISCS_BACHD ;  P38033, ISCS_BACSU ;
DR   B8D8F9, ISCS_BUCA5 ;  P57657, ISCS_BUCAI ;  O51886, ISCS_BUCAP ;
DR   B8D8B6, ISCS_BUCAT ;  Q89A19, ISCS_BUCBP ;  A7FWJ9, ISCS_CLOB1 ;
DR   A5I4Z9, ISCS_CLOBH ;  C1FTC4, ISCS_CLOBJ ;  Q486Z0, ISCS_COLP3 ;
DR   Q47EN5, ISCS_DECAR ;  B8DZS1, ISCS_DICTD ;  A7ZPX4, ISCS_ECO24 ;
DR   B7UGX6, ISCS_ECO27 ;  B7MIM0, ISCS_ECO45 ;  B7LDC2, ISCS_ECO55 ;
DR   P0A6B9, ISCS_ECO57 ;  B5Z104, ISCS_ECO5E ;  B7NRH9, ISCS_ECO7I ;
DR   B7MYG3, ISCS_ECO81 ;  B7M7N3, ISCS_ECO8A ;  C4ZXA5, ISCS_ECOBW ;
DR   B1XB05, ISCS_ECODH ;  A8A336, ISCS_ECOHS ;  Q0TEV5, ISCS_ECOL5 ;
DR   P0A6B8, ISCS_ECOL6 ;  B1IWD1, ISCS_ECOLC ;  P0A6B7, ISCS_ECOLI ;
DR   B7N6B7, ISCS_ECOLU ;  B6I5A2, ISCS_ECOSE ;  B1LNI6, ISCS_ECOSM ;
DR   C5BEU5, ISCS_EDWI9 ;  Q2GGJ4, ISCS_EHRCR ;  A4WDB1, ISCS_ENT38 ;
DR   A7MGX8, ISCS_ENTS8 ;  Q6D259, ISCS_ERWCT ;  B2VI32, ISCS_ERWT9 ;
DR   B7LKA9, ISCS_ESCF3 ;  Q7VMA9, ISCS_HAEDU ;  A5UAA8, ISCS_HAEIE ;
DR   A5UGI1, ISCS_HAEIG ;  Q57337, ISCS_HAEIN ;  B8F356, ISCS_HAEPS ;
DR   Q0I1L2, ISCS_HAES1 ;  B0UVL5, ISCS_HAES2 ;  B6JKF2, ISCS_HELP2 ;
DR   Q9ZML2, ISCS_HELPJ ;  B2US50, ISCS_HELPS ;  O25008, ISCS_HELPY ;
DR   B5XNJ7, ISCS_KLEP3 ;  A6TCF1, ISCS_KLEP7 ;  Q65RS7, ISCS_MANSM ;
DR   Q60C64, ISCS_METCA ;  Q1H361, ISCS_METFK ;  P57795, ISCS_METTE ;
DR   Q5F8X4, ISCS_NEIG1 ;  B4RMB8, ISCS_NEIG2 ;  A9M029, ISCS_NEIM0 ;
DR   Q9JTX0, ISCS_NEIMA ;  Q9JYY0, ISCS_NEIMB ;  A1KUK1, ISCS_NEIMF ;
DR   P57803, ISCS_PASMU ;  C6DBJ1, ISCS_PECCP ;  Q7N224, ISCS_PHOLL ;
DR   Q6LU62, ISCS_PHOPR ;  B4EZU8, ISCS_PROMH ;  Q48M05, ISCS_PSE14 ;
DR   A6V0U8, ISCS_PSEA7 ;  B7UWH7, ISCS_PSEA8 ;  Q02RW8, ISCS_PSEAB ;
DR   Q9HXI8, ISCS_PSEAE ;  Q1IEJ2, ISCS_PSEE4 ;  Q4K6T8, ISCS_PSEF5 ;
DR   C3K1M5, ISCS_PSEFS ;  Q3IFI3, ISCS_PSEHT ;  A4XY43, ISCS_PSEMY ;
DR   A5VYS4, ISCS_PSEP1 ;  Q3K7A5, ISCS_PSEPF ;  B0KPH6, ISCS_PSEPG ;
DR   Q88PK8, ISCS_PSEPK ;  B1JDR3, ISCS_PSEPW ;  Q887A1, ISCS_PSESM ;
DR   Q4ZX34, ISCS_PSEU2 ;  A4VNY2, ISCS_PSEU5 ;  A1SUI4, ISCS_PSYIN ;
DR   C3PNQ8, ISCS_RICAE ;  A8GNU0, ISCS_RICAH ;  A8GWB2, ISCS_RICB8 ;
DR   Q1RHY6, ISCS_RICBR ;  A8EYH9, ISCS_RICCK ;  Q92HP1, ISCS_RICCN ;
DR   Q4UL77, ISCS_RICFE ;  A8F204, ISCS_RICM5 ;  Q9ZD60, ISCS_RICPR ;
DR   C4K1Z7, ISCS_RICPU ;  B0BXX6, ISCS_RICRO ;  A8GSG4, ISCS_RICRS ;
DR   Q68WP6, ISCS_RICTY ;  O54055, ISCS_RUMFL ;  A1AWM1, ISCS_RUTMC ;
DR   B5F1C0, ISCS_SALA4 ;  A9MHJ4, ISCS_SALAR ;  Q57LG9, ISCS_SALCH ;
DR   B5FR85, ISCS_SALDC ;  B5R5A2, ISCS_SALEP ;  B5RD12, ISCS_SALG2 ;
DR   B4TDB6, ISCS_SALHS ;  B4T0S2, ISCS_SALNS ;  Q5PNG1, ISCS_SALPA ;
DR   A9N1X5, ISCS_SALPB ;  C0PYK7, ISCS_SALPC ;  B5BAW6, ISCS_SALPK ;
DR   B4TRX5, ISCS_SALSV ;  Q8Z4N0, ISCS_SALTI ;  Q8ZN40, ISCS_SALTY ;
DR   A8GHY3, ISCS_SERP5 ;  A1S544, ISCS_SHEAM ;  B8E9D2, ISCS_SHEB2 ;
DR   A3D577, ISCS_SHEB5 ;  A6WNY5, ISCS_SHEB8 ;  A9L3R0, ISCS_SHEB9 ;
DR   Q12P83, ISCS_SHEDO ;  Q080P6, ISCS_SHEFN ;  B0TNY1, ISCS_SHEHH ;
DR   A3QFD5, ISCS_SHELP ;  Q8EEU9, ISCS_SHEON ;  A8H2M6, ISCS_SHEPA ;
DR   A4Y7D7, ISCS_SHEPC ;  B8CMW5, ISCS_SHEPW ;  A0KXJ0, ISCS_SHESA ;
DR   A8FXA5, ISCS_SHESH ;  Q0HJF4, ISCS_SHESM ;  Q0HVP4, ISCS_SHESR ;
DR   A1RJ52, ISCS_SHESW ;  B1KNI3, ISCS_SHEWM ;  B2TXV5, ISCS_SHIB3 ;
DR   Q0T1Y9, ISCS_SHIF8 ;  P0A6C0, ISCS_SHIFL ;  C4L7K2, ISCS_TOLAT ;
DR   A5CWM6, ISCS_VESOH ;  A5F3G4, ISCS_VIBC3 ;  Q9KTY2, ISCS_VIBCH ;
DR   C3LT01, ISCS_VIBCM ;  A7MU48, ISCS_VIBHB ;  Q87S28, ISCS_VIBPA ;
DR   B7VJS6, ISCS_VIBSL ;  Q8DEY7, ISCS_VIBVU ;  Q7MNG2, ISCS_VIBVY ;
DR   O49543, NFS1_ARATH ;  O60028, NFS1_ASHGO ;  P87185, NFS1_CANAL ;
DR   P87187, NFS1_CANMA ;  Q54X04, NFS1_DICDI ;  Q9VKD3, NFS1_DROME ;
DR   Q8SQS2, NFS1_ENCCU ;  Q9Y697, NFS1_HUMAN ;  Q9Z1J3, NFS1_MOUSE ;
DR   Q5RDE7, NFS1_PONAB ;  Q99P39, NFS1_RAT   ;  O74351, NFS1_SCHPO ;
DR   B0YLW6, NFS1_TRAHO ;  P25374, NFS1_YEAST ;  Q93WX6, NFS2_ARATH ;
DR   Q44507, NIFS1_ANAVT;  Q44482, NIFS2_ANAVT;  Q43884, NIFS_ANAAZ ;
DR   P70727, NIFS_AZOBR ;  P23120, NIFS_AZOCH ;  P05341, NIFS_AZOVI ;
DR   P37030, NIFS_BRAJA ;  Q52069, NIFS_ENTAG ;  Q9Z5X5, NIFS_FRASE ;
DR   P57794, NIFS_GLUDA ;  P05344, NIFS_KLEPN ;  P12623, NIFS_NOSS1 ;
DR   P55690, NIFS_RHISN ;  Q07177, NIFS_RHOCA ;  Q01179, NIFS_RHOSH ;
DR   A8AH80, SUFS_CITK8 ;  Q9EXP2, SUFS_DICD3 ;  A7ZME5, SUFS_ECO24 ;
DR   B7US19, SUFS_ECO27 ;  B7MA32, SUFS_ECO45 ;  B7L5N2, SUFS_ECO55 ;
DR   Q7ADI4, SUFS_ECO57 ;  B5Z4B3, SUFS_ECO5E ;  B7NTV6, SUFS_ECO7I ;
DR   B7MV59, SUFS_ECO81 ;  B7M0N5, SUFS_ECO8A ;  C4ZYE2, SUFS_ECOBW ;
DR   B1XFY8, SUFS_ECODH ;  A8A0M6, SUFS_ECOHS ;  A1ABL8, SUFS_ECOK1 ;
DR   Q0THE9, SUFS_ECOL5 ;  Q8FH54, SUFS_ECOL6 ;  B1IQ76, SUFS_ECOLC ;
DR   P77444, SUFS_ECOLI ;  B7N516, SUFS_ECOLU ;  B6IBB9, SUFS_ECOSE ;
DR   B1LE56, SUFS_ECOSM ;  Q1RBB6, SUFS_ECOUT ;  A4W9R3, SUFS_ENT38 ;
DR   A7MF59, SUFS_ENTS8 ;  Q6D625, SUFS_ERWCT ;  B7LQ96, SUFS_ESCF3 ;
DR   B5XQH2, SUFS_KLEP3 ;  A6TAE4, SUFS_KLEP7 ;  C6DKM6, SUFS_PECCP ;
DR   Q7N3U5, SUFS_PHOLL ;  B5F7C4, SUFS_SALA4 ;  A9MEP3, SUFS_SALAR ;
DR   Q57PR2, SUFS_SALCH ;  B5FIM3, SUFS_SALDC ;  B5QVS9, SUFS_SALEP ;
DR   B5RAT4, SUFS_SALG2 ;  B4TGK9, SUFS_SALHS ;  B4T4R6, SUFS_SALNS ;
DR   A9N142, SUFS_SALPB ;  B4TUT5, SUFS_SALSV ;  Q8XF77, SUFS_SALTI ;
DR   Q7CQN5, SUFS_SALTY ;  A8GDU4, SUFS_SERP5 ;  B2U2I4, SUFS_SHIB3 ;
DR   Q321D9, SUFS_SHIBS ;  Q7UAH4, SUFS_SHIFL ;  Q3Z233, SUFS_SHISS ;
DR   Q8D2J7, SUFS_WIGBR ;  A7FHJ2, SUFS_YERP3 ;  Q1C761, SUFS_YERPA ;
DR   B2K5J4, SUFS_YERPB ;  Q8D0M6, SUFS_YERPE ;  A9QZC9, SUFS_YERPG ;
DR   Q1CIJ6, SUFS_YERPN ;  A4TIP2, SUFS_YERPP ;  Q66A22, SUFS_YERPS ;
DR   B1JJ48, SUFS_YERPY ;
//
ID   2.8.1.8
DE   Lipoyl synthase.
AN   Lipoate synthase.
CA   Protein N(6)-(octanoyl)lysine + 2 sulfur + 2 S-adenosyl-L-methionine =
CA   protein N(6)-(lipoyl)lysine + 2 L-methionine + 2 5'-deoxyadenosine.
CC   -!- Member of the 'AdoMet radical' (radical SAM) family, all members of
CC       which produce the 5'-deoxyadenosin-5'-yl radical and methionine from
CC       AdoMet (i.e. S-adenosylmethionine, or S-(5'-deoxyadenosin-
CC       5'-yl)methionine), by the addition of an electron from an iron-sulfur
CC       center.
CC   -!- The radical is converted into 5'-deoxyadenosine when it abstracts a
CC       hydrogen atom from C-6 and C-8, leaving reactive radicals at these
CC       positions so that they can add sulfur, with inversion of
CC       configuration.
CC   -!- Catalyzes the final step in the de-novo biosynthesis of the lipoyl
CC       cofactor, with the other enzyme involved being EC 2.3.1.181.
CC   -!- Lipoylation is essential for the function of several key enzymes
CC       involved in oxidative metabolism, as it converts apoprotein into the
CC       biologically active holoprotein.
CC   -!- Examples of such lipoylated proteins include pyruvate dehydrogenase
CC       (E(2) domain), 2-oxoglutarate dehydrogenase (E(2) domain),
CC       the branched-chain 2-oxoacid dehydrogenases and the glycine cleavage
CC       system.
CC   -!- An alternative lipoylation pathway involves EC 2.7.7.63, which can
CC       lipoylate apoproteins using exogenous lipoic acid (or its analogs).
DR   B4IUG3, LIAS1_DROYA;  Q3LSN4, LIAS1_PEA  ;  B4PF83, LIAS2_DROYA;
DR   Q3LSN5, LIAS2_PEA  ;  Q16W22, LIAS_AEDAE ;  Q9ZWT1, LIAS_ARATH ;
DR   Q5BIP7, LIAS_BOVIN ;  C3Y3G4, LIAS_BRAFL ;  A8PF69, LIAS_BRUMA ;
DR   Q21452, LIAS_CAEEL ;  A8JGF7, LIAS_CHLRE ;  B0WAU6, LIAS_CULQU ;
DR   Q6PHG4, LIAS_DANRE ;  B3M996, LIAS_DROAN ;  B3NIL9, LIAS_DROER ;
DR   B4J3F3, LIAS_DROGR ;  Q7JQW6, LIAS_DROME ;  B4KYY0, LIAS_DROMO ;
DR   Q2LYK1, LIAS_DROPS ;  B4IAA7, LIAS_DROSE ;  B4MXR6, LIAS_DROWI ;
DR   O43766, LIAS_HUMAN ;  B8A031, LIAS_MAIZE ;  B7FM45, LIAS_MEDTR ;
DR   Q99M04, LIAS_MOUSE ;  A7TDI2, LIAS_NEMVE ;  A2XU53, LIAS_ORYSI ;
DR   Q7XRF1, LIAS_ORYSJ ;  A4RZ86, LIAS_OSTLU ;  A9NNH7, LIAS_PICSI ;
DR   B9H5L9, LIAS_POPTR ;  Q5XIH4, LIAS_RAT   ;  B9RW49, LIAS_RICCO ;
DR   C4PZQ3, LIAS_SCHMA ;  C5Y9R0, LIAS_SORBI ;  B3SBB5, LIAS_TRIAD ;
DR   A5CB81, LIAS_VITVI ;  Q6GQ48, LIAS_XENLA ;  Q89LR6, LIPA1_BRAJA;
DR   Q7NLU2, LIPA1_GLOVI;  Q8YWC1, LIPA1_NOSS1;  B7FRU7, LIPA1_PHATC;
DR   Q7V9Z9, LIPA1_PROMA;  Q7V507, LIPA1_PROMM;  Q7UZY1, LIPA1_PROMP;
DR   Q7U4D9, LIPA1_SYNPX;  P72980, LIPA1_SYNY3;  Q8DL83, LIPA1_THEEB;
DR   Q4DC43, LIPA1_TRYCR;  Q89NW6, LIPA2_BRAJA;  Q7NFJ9, LIPA2_GLOVI;
DR   Q8YXD1, LIPA2_NOSS1;  B7G3Y9, LIPA2_PHATC;  Q7VBJ3, LIPA2_PROMA;
DR   Q7V6S0, LIPA2_PROMM;  Q7V0Z8, LIPA2_PROMP;  Q7U7Q2, LIPA2_SYNPX;
DR   P73572, LIPA2_SYNY3;  Q8DLC2, LIPA2_THEEB;  Q4DYL7, LIPA2_TRYCR;
DR   A1TJ31, LIPA_ACIAC ;  Q1II13, LIPA_ACIBL ;  A0LTD9, LIPA_ACIC1 ;
DR   A5G2D2, LIPA_ACICJ ;  B9MB93, LIPA_ACIET ;  B7J7N7, LIPA_ACIF2 ;
DR   B5EMR4, LIPA_ACIF5 ;  A1W2S7, LIPA_ACISJ ;  A3N2P1, LIPA_ACTP2 ;
DR   B3H2J0, LIPA_ACTP7 ;  B0BRR9, LIPA_ACTPJ ;  A6VM79, LIPA_ACTSZ ;
DR   A0KNA3, LIPA_AERHH ;  Q9Y9E3, LIPA_AERPE ;  A4SJV5, LIPA_AERS4 ;
DR   B9JEZ6, LIPA_AGRRK ;  Q8UFG1, LIPA_AGRT5 ;  B9JW84, LIPA_AGRVS ;
DR   C0NXP6, LIPA_AJECG ;  C6HLY2, LIPA_AJECH ;  C5GPL2, LIPA_AJEDR ;
DR   C5JVC1, LIPA_AJEDS ;  Q0VN36, LIPA_ALCBS ;  Q0A8A4, LIPA_ALHEH ;
DR   B6EIF3, LIPA_ALISL ;  A6TWC9, LIPA_ALKMQ ;  B4RX69, LIPA_ALTMD ;
DR   Q2IIW6, LIPA_ANADE ;  A7HBU9, LIPA_ANADF ;  Q5PAD4, LIPA_ANAMM ;
DR   Q2GKX7, LIPA_ANAPZ ;  B9MQ24, LIPA_ANATD ;  O67368, LIPA_AQUAE ;
DR   Q5P4B8, LIPA_AROAE ;  C5FZJ2, LIPA_ARTOC ;  Q74ZH6, LIPA_ASHGO ;
DR   A1CJC4, LIPA_ASPCL ;  B0XYY2, LIPA_ASPFC ;  B8NUL8, LIPA_ASPFN ;
DR   Q4WWP1, LIPA_ASPFU ;  A5ABM5, LIPA_ASPNC ;  Q2U4H2, LIPA_ASPOR ;
DR   A8I4L8, LIPA_AZOC5 ;  A1K1U7, LIPA_AZOSB ;  C1DMR1, LIPA_AZOVD ;
DR   A7Z8E8, LIPA_BACA2 ;  C3PDK2, LIPA_BACAA ;  C3LCA6, LIPA_BACAC ;
DR   A0RKF7, LIPA_BACAH ;  Q81XM8, LIPA_BACAN ;  B7JDM3, LIPA_BACC0 ;
DR   Q72YB2, LIPA_BACC1 ;  B7IMZ7, LIPA_BACC2 ;  C1EY56, LIPA_BACC3 ;
DR   B7HCZ6, LIPA_BACC4 ;  B7HUW3, LIPA_BACC7 ;  A7GUG3, LIPA_BACCN ;
DR   B9J3H2, LIPA_BACCQ ;  Q816A0, LIPA_BACCR ;  Q631Z7, LIPA_BACCZ ;
DR   Q5LGU6, LIPA_BACFN ;  Q64XQ0, LIPA_BACFR ;  Q9K7C9, LIPA_BACHD ;
DR   Q6HBT4, LIPA_BACHK ;  A8FH34, LIPA_BACP2 ;  Q5WDS6, LIPA_BACSK ;
DR   O32129, LIPA_BACSU ;  Q8A029, LIPA_BACTN ;  A6L1U8, LIPA_BACV8 ;
DR   A9VNX6, LIPA_BACWK ;  A1USA0, LIPA_BARBK ;  Q6G401, LIPA_BARHE ;
DR   Q6G166, LIPA_BARQU ;  A9IS79, LIPA_BART1 ;  Q1LTM3, LIPA_BAUCH ;
DR   B2IB58, LIPA_BEII9 ;  C5C4Y6, LIPA_BEUC1 ;  Q2L1D8, LIPA_BORA1 ;
DR   Q7WR00, LIPA_BORBR ;  Q7W222, LIPA_BORPA ;  Q7W0K8, LIPA_BORPE ;
DR   A5EIM5, LIPA_BRASB ;  A4YUR5, LIPA_BRASO ;  B2S5X5, LIPA_BRUA1 ;
DR   Q2YPV8, LIPA_BRUA2 ;  Q57D15, LIPA_BRUAB ;  A9M5D7, LIPA_BRUC2 ;
DR   C0RJ95, LIPA_BRUMB ;  P65281, LIPA_BRUME ;  A5VQP8, LIPA_BRUO2 ;
DR   B0CGS4, LIPA_BRUSI ;  P65282, LIPA_BRUSU ;  B8D962, LIPA_BUCA5 ;
DR   P57357, LIPA_BUCAI ;  Q8K9Q2, LIPA_BUCAP ;  B8D7G6, LIPA_BUCAT ;
DR   Q89AL7, LIPA_BUCBP ;  Q057Q7, LIPA_BUCCC ;  A3MR17, LIPA_BURM7 ;
DR   A2S5Y9, LIPA_BURM9 ;  Q62N16, LIPA_BURMA ;  A1V016, LIPA_BURMS ;
DR   A3NQX6, LIPA_BURP0 ;  Q3JWL1, LIPA_BURP1 ;  A3N576, LIPA_BURP6 ;
DR   Q9EYP3, LIPA_BURPS ;  Q2T1K5, LIPA_BURTA ;  A4XHV2, LIPA_CALS8 ;
DR   P0CH67, LIPA_CANAL ;  P0CH68, LIPA_CANAW ;  B9WFS9, LIPA_CANDC ;
DR   Q6FPY0, LIPA_CANGA ;  C5M276, LIPA_CANTT ;  B8GW82, LIPA_CAUCN ;
DR   Q9A7I8, LIPA_CAUCR ;  A9WEM1, LIPA_CHLAA ;  Q5L4V4, LIPA_CHLAB ;
DR   B8G782, LIPA_CHLAD ;  Q3ARP5, LIPA_CHLCH ;  Q821K6, LIPA_CHLCV ;
DR   Q256D6, LIPA_CHLFF ;  B3ECK5, LIPA_CHLL2 ;  Q9PJI2, LIPA_CHLMU ;
DR   B3QNE9, LIPA_CHLP8 ;  A1BFY3, LIPA_CHLPD ;  Q9Z774, LIPA_CHLPN ;
DR   B9LM70, LIPA_CHLSY ;  B0B8D2, LIPA_CHLT2 ;  Q3KLD9, LIPA_CHLTA ;
DR   B0BA11, LIPA_CHLTB ;  Q8KDH2, LIPA_CHLTE ;  O84562, LIPA_CHLTR ;
DR   Q7NTF9, LIPA_CHRVO ;  A8AJH6, LIPA_CITK8 ;  C4YA37, LIPA_CLAL4 ;
DR   A5CQ99, LIPA_CLAM3 ;  B0RE24, LIPA_CLAMS ;  C5PIN8, LIPA_COCP7 ;
DR   Q484R8, LIPA_COLP3 ;  A8N1T1, LIPA_COPC7 ;  C3PHK6, LIPA_CORA7 ;
DR   P61194, LIPA_CORDI ;  Q8FNP4, LIPA_COREF ;  A4QFS3, LIPA_CORGB ;
DR   Q8NNJ0, LIPA_CORGL ;  Q4JWE0, LIPA_CORJK ;  C4LI04, LIPA_CORK4 ;
DR   B1VHG8, LIPA_CORU7 ;  B6J7S3, LIPA_COXB1 ;  B6IZL4, LIPA_COXB2 ;
DR   A9KFW5, LIPA_COXBN ;  A9NDX8, LIPA_COXBR ;  Q83C63, LIPA_COXBU ;
DR   P0CO59, LIPA_CRYNB ;  P0CO58, LIPA_CRYNJ ;  Q0KFE6, LIPA_CUPNH ;
DR   Q477G5, LIPA_CUPPJ ;  B2AG37, LIPA_CUPTR ;  Q11Q84, LIPA_CYTH3 ;
DR   B5RUV1, LIPA_DEBHA ;  Q47JD5, LIPA_DECAR ;  Q1IXJ7, LIPA_DEIGD ;
DR   Q9RWA4, LIPA_DEIRA ;  A9BPT7, LIPA_DELAS ;  Q30XT6, LIPA_DESDG ;
DR   Q6ARK0, LIPA_DESPS ;  A4J247, LIPA_DESRM ;  Q72DM4, LIPA_DESVH ;
DR   A1VF79, LIPA_DESVV ;  A5EVQ3, LIPA_DICNV ;  A7ZJ15, LIPA_ECO24 ;
DR   B7UKR9, LIPA_ECO27 ;  B7MFQ1, LIPA_ECO45 ;  B7L9H2, LIPA_ECO55 ;
DR   P60718, LIPA_ECO57 ;  B5YQH9, LIPA_ECO5E ;  B7NLY7, LIPA_ECO7I ;
DR   B7MRR5, LIPA_ECO81 ;  B7M5F5, LIPA_ECO8A ;  C4ZWB5, LIPA_ECOBW ;
DR   A7ZXQ4, LIPA_ECOHS ;  A1A8Q3, LIPA_ECOK1 ;  Q0TK45, LIPA_ECOL5 ;
DR   P60717, LIPA_ECOL6 ;  B1IYI0, LIPA_ECOLC ;  P60716, LIPA_ECOLI ;
DR   B7N9N3, LIPA_ECOLU ;  B6I137, LIPA_ECOSE ;  B1LKL9, LIPA_ECOSM ;
DR   Q1RET3, LIPA_ECOUT ;  C5BGD9, LIPA_EDWI9 ;  Q3YRT2, LIPA_EHRCJ ;
DR   Q2GGX7, LIPA_EHRCR ;  Q5FFK4, LIPA_EHRRG ;  Q5HB02, LIPA_EHRRW ;
DR   Q5AQE4, LIPA_EMENI ;  A4W814, LIPA_ENT38 ;  A7MNP9, LIPA_ENTS8 ;
DR   Q6D7M8, LIPA_ERWCT ;  B2VBK1, LIPA_ERWT9 ;  Q2NAD7, LIPA_ERYLH ;
DR   B7LLI3, LIPA_ESCF3 ;  A5FNF9, LIPA_FLAJ1 ;  A6GZL9, LIPA_FLAPJ ;
DR   Q0RFE8, LIPA_FRAAA ;  B0TZD6, LIPA_FRAP2 ;  Q2J897, LIPA_FRASC ;
DR   Q14IH3, LIPA_FRAT1 ;  A7NBV0, LIPA_FRATF ;  Q2A3R2, LIPA_FRATH ;
DR   B2SH72, LIPA_FRATM ;  A0Q6Q2, LIPA_FRATN ;  Q0BM68, LIPA_FRATO ;
DR   Q5NH21, LIPA_FRATT ;  A4IY90, LIPA_FRATW ;  B5EAX0, LIPA_GEOBB ;
DR   Q5KVM7, LIPA_GEOKA ;  B3E6X0, LIPA_GEOLS ;  Q39QW1, LIPA_GEOMG ;
DR   B9M4F4, LIPA_GEOSF ;  P61196, LIPA_GEOSL ;  C6DYX9, LIPA_GEOSM ;
DR   C5D7H5, LIPA_GEOSW ;  A4ISG5, LIPA_GEOTN ;  A5GCS6, LIPA_GEOUR ;
DR   Q5FNM1, LIPA_GLUOX ;  Q0BSW6, LIPA_GRABC ;  A0M4W4, LIPA_GRAFK ;
DR   Q7VKB1, LIPA_HAEDU ;  Q4QPL8, LIPA_HAEI8 ;  A5UBB2, LIPA_HAEIE ;
DR   A5UFJ8, LIPA_HAEIG ;  P44463, LIPA_HAEIN ;  B8F679, LIPA_HAEPS ;
DR   Q0I1H8, LIPA_HAES1 ;  B0UVP7, LIPA_HAES2 ;  Q2SA38, LIPA_HAHCH ;
DR   A1WT98, LIPA_HALHL ;  B9LR22, LIPA_HALLT ;  B0R7C4, LIPA_HALS3 ;
DR   Q9HN78, LIPA_HALSA ;  A4G9C6, LIPA_HERAR ;  Q5QYE5, LIPA_IDILO ;
DR   A6T345, LIPA_JANMA ;  A6WD63, LIPA_KINRD ;  B5XZS6, LIPA_KLEP3 ;
DR   A6T689, LIPA_KLEP7 ;  Q6CLS2, LIPA_KLULA ;  B2GJ88, LIPA_KOCRD ;
DR   B0CQH8, LIPA_LACBS ;  C5DGZ5, LIPA_LACTC ;  C1D5T3, LIPA_LARHH ;
DR   Q5X703, LIPA_LEGPA ;  A5IGG3, LIPA_LEGPC ;  Q5ZXI6, LIPA_LEGPH ;
DR   Q5WYF5, LIPA_LEGPL ;  A4H9Z3, LIPA_LEIBR ;  A4HY57, LIPA_LEIIN ;
DR   Q4QDI6, LIPA_LEIMA ;  Q6AFG7, LIPA_LEIXX ;  B0SGV6, LIPA_LEPBA ;
DR   Q04T63, LIPA_LEPBJ ;  Q051I5, LIPA_LEPBL ;  B0SQ03, LIPA_LEPBP ;
DR   B1XX30, LIPA_LEPCP ;  Q72RU2, LIPA_LEPIC ;  Q8F3V7, LIPA_LEPIN ;
DR   A5E450, LIPA_LODEL ;  B9EAJ9, LIPA_MACCJ ;  A0L509, LIPA_MAGSM ;
DR   Q65RH7, LIPA_MANSM ;  A1U380, LIPA_MARAV ;  Q0APQ9, LIPA_MARMM ;
DR   Q11HV6, LIPA_MESSB ;  B7KRC9, LIPA_METC4 ;  Q60CJ6, LIPA_METCA ;
DR   A9W6I4, LIPA_METEP ;  Q1GYC1, LIPA_METFK ;  B8IDD6, LIPA_METNO ;
DR   B1ZEL4, LIPA_METPB ;  B1LWN4, LIPA_METRJ ;  B8EJU1, LIPA_METSB ;
DR   C5CCN0, LIPA_MICLC ;  Q2RHM6, LIPA_MOOTA ;  A0QEY6, LIPA_MYCA1 ;
DR   P65284, LIPA_MYCBO ;  A1KKR0, LIPA_MYCBP ;  C1AQD3, LIPA_MYCBT ;
DR   A4TBK7, LIPA_MYCGI ;  B8ZQJ9, LIPA_MYCLB ;  O32962, LIPA_MYCLE ;
DR   B2HHL4, LIPA_MYCMM ;  P61197, LIPA_MYCPA ;  A0R075, LIPA_MYCS2 ;
DR   A3Q1S8, LIPA_MYCSJ ;  A1UIB4, LIPA_MYCSK ;  Q1B6R1, LIPA_MYCSS ;
DR   A5U4P6, LIPA_MYCTA ;  P65283, LIPA_MYCTU ;  A0PNH7, LIPA_MYCUA ;
DR   Q1D4N0, LIPA_MYXXD ;  Q3IU11, LIPA_NATPD ;  C7Z527, LIPA_NECH7 ;
DR   Q5F8I0, LIPA_NEIG1 ;  B4RLK9, LIPA_NEIG2 ;  A9LZ95, LIPA_NEIM0 ;
DR   Q9JUC8, LIPA_NEIMA ;  Q9JZA5, LIPA_NEIMB ;  A1D855, LIPA_NEOFI ;
DR   Q2GE84, LIPA_NEOSM ;  Q7SF84, LIPA_NEUCR ;  Q0AI05, LIPA_NITEC ;
DR   Q82UJ5, LIPA_NITEU ;  Q1QMA2, LIPA_NITHX ;  Q2Y7I9, LIPA_NITMU ;
DR   Q3J7W4, LIPA_NITOC ;  Q3SSP1, LIPA_NITWN ;  Q5YZ59, LIPA_NOCFA ;
DR   A1SJ19, LIPA_NOCSJ ;  Q2G712, LIPA_NOVAD ;  Q8ERL8, LIPA_OCEIH ;
DR   A6X0M7, LIPA_OCHA4 ;  B6JDY1, LIPA_OLICO ;  A5CCM4, LIPA_ORITB ;
DR   B3CQP5, LIPA_ORITI ;  C1H594, LIPA_PARBA ;  C1GFM3, LIPA_PARBD ;
DR   C0SDG9, LIPA_PARBP ;  A6LE09, LIPA_PARD8 ;  A1B1T3, LIPA_PARDP ;
DR   A7HXW0, LIPA_PARL1 ;  Q6MEX3, LIPA_PARUW ;  P57978, LIPA_PASMU ;
DR   B1X4X1, LIPA_PAUCH ;  C6DBV6, LIPA_PECCP ;  Q57390, LIPA_PELCD ;
DR   Q3B3Y5, LIPA_PELLD ;  B4SHB4, LIPA_PELPB ;  A1AMT5, LIPA_PELPD ;
DR   Q4FM35, LIPA_PELUB ;  B6HFQ1, LIPA_PENCW ;  B6QSZ4, LIPA_PENMQ ;
DR   Q0V6U4, LIPA_PHANO ;  B4RBV1, LIPA_PHEZH ;  Q7N767, LIPA_PHOLL ;
DR   Q6LN87, LIPA_PHOPR ;  D0NP70, LIPA_PHYIN ;  A5DGI1, LIPA_PICGU ;
DR   C4QYF2, LIPA_PICPG ;  A3GGJ5, LIPA_PICST ;  Q6L1L7, LIPA_PICTO ;
DR   Q8IDQ0, LIPA_PLAF7 ;  B3L8F2, LIPA_PLAKH ;  A5K883, LIPA_PLAVI ;
DR   Q7RBD6, LIPA_PLAYO ;  B2AT43, LIPA_PODAN ;  A1VIT9, LIPA_POLNA ;
DR   B2RKU2, LIPA_PORG3 ;  Q7MWT4, LIPA_PORGI ;  Q6A9X0, LIPA_PROAC ;
DR   A8G714, LIPA_PROM2 ;  B4EV01, LIPA_PROMH ;  A4SEG3, LIPA_PROVI ;
DR   Q48DM6, LIPA_PSE14 ;  Q15VL3, LIPA_PSEA6 ;  A6V0B4, LIPA_PSEA7 ;
DR   B7V9C1, LIPA_PSEA8 ;  Q02SG3, LIPA_PSEAB ;  Q9HX25, LIPA_PSEAE ;
DR   Q1I4G1, LIPA_PSEE4 ;  C3K2L8, LIPA_PSEFS ;  Q3IJ81, LIPA_PSEHT ;
DR   A4XYX3, LIPA_PSEMY ;  A5W9I5, LIPA_PSEP1 ;  Q3K6A4, LIPA_PSEPF ;
DR   Q88DM5, LIPA_PSEPK ;  B1J144, LIPA_PSEPW ;  Q87VW7, LIPA_PSESM ;
DR   Q4ZN84, LIPA_PSEU2 ;  A4VQZ6, LIPA_PSEU5 ;  Q4FTQ5, LIPA_PSYA2 ;
DR   Q1QCS6, LIPA_PSYCK ;  A1SZ17, LIPA_PSYIN ;  A5WDV8, LIPA_PSYWF ;
DR   Q8ZUR9, LIPA_PYRAE ;  A4WK38, LIPA_PYRAR ;  A3MW09, LIPA_PYRCJ ;
DR   B2WBE8, LIPA_PYRTR ;  Q1LSC9, LIPA_RALME ;  B2UE01, LIPA_RALPJ ;
DR   Q8Y2L3, LIPA_RALSO ;  B3PYS0, LIPA_RHIE6 ;  Q2K8V9, LIPA_RHIEC ;
DR   Q1MH26, LIPA_RHIL3 ;  Q98MY2, LIPA_RHILO ;  B5ZNB1, LIPA_RHILW ;
DR   Q92Q94, LIPA_RHIME ;  Q7UH37, LIPA_RHOBA ;  B6IQ36, LIPA_RHOCS ;
DR   Q2IW20, LIPA_RHOP2 ;  Q07MZ5, LIPA_RHOP5 ;  P61198, LIPA_RHOPA ;
DR   Q214R4, LIPA_RHOPB ;  Q137C6, LIPA_RHOPS ;  B3QIL2, LIPA_RHOPT ;
DR   Q2RT68, LIPA_RHORT ;  A3PJL9, LIPA_RHOS1 ;  Q3J2P4, LIPA_RHOS4 ;
DR   A4WRC8, LIPA_RHOS5 ;  B9KSE2, LIPA_RHOSK ;  C3PLL8, LIPA_RICAE ;
DR   A8GPR5, LIPA_RICAH ;  A8GUH3, LIPA_RICB8 ;  Q1RGX4, LIPA_RICBR ;
DR   A8EZU2, LIPA_RICCK ;  Q92GH8, LIPA_RICCN ;  Q4UK97, LIPA_RICFE ;
DR   A8F2M4, LIPA_RICM5 ;  O05959, LIPA_RICPR ;  C4K1I0, LIPA_RICPU ;
DR   B0BV26, LIPA_RICRO ;  A8GTI8, LIPA_RICRS ;  Q68W08, LIPA_RICTY ;
DR   A5US48, LIPA_ROSS1 ;  Q1AT13, LIPA_RUBXD ;  A1AWI8, LIPA_RUTMC ;
DR   A4FA70, LIPA_SACEN ;  B5EZ72, LIPA_SALA4 ;  A9MKE4, LIPA_SALAR ;
DR   Q57RU3, LIPA_SALCH ;  B5FMM8, LIPA_SALDC ;  B5QVN4, LIPA_SALEP ;
DR   B5R7Y1, LIPA_SALG2 ;  B4TAI5, LIPA_SALHS ;  B4SYJ0, LIPA_SALNS ;
DR   Q5PM97, LIPA_SALPA ;  A9MV74, LIPA_SALPB ;  C0PW62, LIPA_SALPC ;
DR   B5BCG1, LIPA_SALPK ;  B4TPA3, LIPA_SALSV ;  Q8Z8I3, LIPA_SALTI ;
DR   Q8ZR04, LIPA_SALTY ;  B6K4J2, LIPA_SCHJY ;  O13642, LIPA_SCHPO ;
DR   A7EV21, LIPA_SCLS1 ;  A8GB09, LIPA_SERP5 ;  A1S8U1, LIPA_SHEAM ;
DR   B8E4W4, LIPA_SHEB2 ;  A3D7P9, LIPA_SHEB5 ;  A6WRL2, LIPA_SHEB8 ;
DR   A9L014, LIPA_SHEB9 ;  Q12QX1, LIPA_SHEDO ;  Q087L5, LIPA_SHEFN ;
DR   B0TR57, LIPA_SHEHH ;  A3QH60, LIPA_SHELP ;  Q8EHQ6, LIPA_SHEON ;
DR   A8H7D5, LIPA_SHEPA ;  A4Y9G2, LIPA_SHEPC ;  B8CSH7, LIPA_SHEPW ;
DR   A0KTV4, LIPA_SHESA ;  A8FZ23, LIPA_SHESH ;  Q0HLK3, LIPA_SHESM ;
DR   Q0HXV7, LIPA_SHESR ;  A1RGT2, LIPA_SHESW ;  B1KDX3, LIPA_SHEWM ;
DR   B2TTI9, LIPA_SHIB3 ;  Q324R5, LIPA_SHIBS ;  Q32IV2, LIPA_SHIDS ;
DR   Q0T6N8, LIPA_SHIF8 ;  P60719, LIPA_SHIFL ;  Q3Z4G4, LIPA_SHISS ;
DR   Q1GGW2, LIPA_SILST ;  A6U8F5, LIPA_SINMW ;  Q2NUV8, LIPA_SODGM ;
DR   A9FD62, LIPA_SORC5 ;  D1Z4I6, LIPA_SORMK ;  Q1GTM7, LIPA_SPHAL ;
DR   A5V2U6, LIPA_SPHWW ;  A7X0C7, LIPA_STAA1 ;  A6U030, LIPA_STAA2 ;
DR   Q2FIE9, LIPA_STAA3 ;  Q2FZX4, LIPA_STAA8 ;  A5IRA1, LIPA_STAA9 ;
DR   Q2YWR5, LIPA_STAAB ;  Q5HHG0, LIPA_STAAC ;  A6QFD6, LIPA_STAAE ;
DR   P65285, LIPA_STAAM ;  P65286, LIPA_STAAN ;  Q6GIG3, LIPA_STAAR ;
DR   Q6GB01, LIPA_STAAS ;  A8Z1I3, LIPA_STAAT ;  P65287, LIPA_STAAW ;
DR   B9DIX8, LIPA_STACT ;  Q5HQN7, LIPA_STAEQ ;  Q8CPW4, LIPA_STAES ;
DR   Q4L4T8, LIPA_STAHJ ;  Q49W64, LIPA_STAS1 ;  Q82AP7, LIPA_STRAW ;
DR   Q9S2P2, LIPA_STRCO ;  B1VZM3, LIPA_STRGG ;  B4SJ16, LIPA_STRM5 ;
DR   B2FUS8, LIPA_STRMK ;  Q4JBV4, LIPA_SULAC ;  A8Z609, LIPA_SULMW ;
DR   Q97U63, LIPA_SULSO ;  Q67MF5, LIPA_SYMTH ;  A5GW06, LIPA_SYNR3 ;
DR   B8MLU5, LIPA_TALSN ;  Q47R88, LIPA_THEFY ;  Q72GV1, LIPA_THET2 ;
DR   Q5SLQ4, LIPA_THET8 ;  Q8R9E1, LIPA_THETN ;  Q31F42, LIPA_THICR ;
DR   Q3SM23, LIPA_THIDA ;  B8GMV6, LIPA_THISH ;  C4LCC5, LIPA_TOLAT ;
DR   Q86G50, LIPA_TOXGO ;  P61199, LIPA_TREDE ;  Q83NN8, LIPA_TROW8 ;
DR   Q83MU9, LIPA_TROWT ;  Q388A7, LIPA_TRYB2 ;  D0A0G6, LIPA_TRYB9 ;
DR   Q0W150, LIPA_UNCMA ;  C4JE77, LIPA_UNCRE ;  C5CP21, LIPA_VARPS ;
DR   A1WF48, LIPA_VEREI ;  A5CWR6, LIPA_VESOH ;  A5F2Y0, LIPA_VIBC3 ;
DR   Q9KTF9, LIPA_VIBCH ;  C3LTJ1, LIPA_VIBCM ;  Q5E6V9, LIPA_VIBF1 ;
DR   B5FBJ6, LIPA_VIBFM ;  A7MY96, LIPA_VIBHB ;  Q87RR1, LIPA_VIBPA ;
DR   B7VKE6, LIPA_VIBSL ;  Q8DFD1, LIPA_VIBVU ;  Q7MN17, LIPA_VIBVY ;
DR   Q8D325, LIPA_WIGBR ;  P61200, LIPA_WOLPM ;  B3CP16, LIPA_WOLPP ;
DR   Q5GSY2, LIPA_WOLTR ;  C0R2Q4, LIPA_WOLWR ;  Q8PPL8, LIPA_XANAC ;
DR   Q3BXQ3, LIPA_XANC5 ;  Q4UYT2, LIPA_XANC8 ;  B0RNP9, LIPA_XANCB ;
DR   Q8P590, LIPA_XANCP ;  Q2NYZ2, LIPA_XANOM ;  Q5GVR7, LIPA_XANOR ;
DR   A7IM78, LIPA_XANP2 ;  B2I923, LIPA_XYLF2 ;  Q9PDW0, LIPA_XYLFA ;
DR   B0U641, LIPA_XYLFM ;  Q87DZ9, LIPA_XYLFT ;  Q6C6C6, LIPA_YARLI ;
DR   B3LJM6, LIPA_YEAS1 ;  C7GWI3, LIPA_YEAS2 ;  B5VS81, LIPA_YEAS6 ;
DR   A6ZP42, LIPA_YEAS7 ;  C8ZGV5, LIPA_YEAS8 ;  P32875, LIPA_YEAST ;
DR   A1JPR9, LIPA_YERE8 ;  A7FKY9, LIPA_YERP3 ;  Q1C507, LIPA_YERPA ;
DR   B2K874, LIPA_YERPB ;  Q8ZDH0, LIPA_YERPE ;  A9R703, LIPA_YERPG ;
DR   Q1CKR6, LIPA_YERPN ;  A4TP09, LIPA_YERPP ;  Q66DF5, LIPA_YERPS ;
DR   B1JGB7, LIPA_YERPY ;  C5DY71, LIPA_ZYGRC ;  Q9RNY7, LIPA_ZYMMO ;
DR   B6TN12, LISC1_MAIZE;  B8AA76, LISC1_ORYSI;  Q5ZAQ2, LISC1_ORYSJ;
DR   B9I666, LISC1_POPTR;  C0PN26, LISC2_MAIZE;  B8B016, LISC2_ORYSI;
DR   Q6L534, LISC2_ORYSJ;  B9N2B0, LISC2_POPTR;  Q8LEE8, LISC_ARATH ;
DR   A8I2V9, LISC_CHLRE ;  A4RW69, LISC_OSTLU ;  B9RX57, LISC_RICCO ;
DR   C5XKZ1, LISC_SORBI ;
//
ID   2.8.2.1
DE   Aryl sulfotransferase.
AN   Phenol sulfotransferase.
AN   Sulfokinase.
CA   3'-phosphoadenylyl sulfate + a phenol = adenosine 3',5'-bisphosphate +
CA   an aryl sulfate.
CC   -!- A number of aromatic compounds can act as acceptors.
CC   -!- Organic hydroxylamines are not substrates (cf. EC 2.8.2.9).
DR   P50227, ST1A1_BOVIN;  Q29476, ST1A1_CANFA;  P50225, ST1A1_HUMAN;
DR   P52846, ST1A1_MACFA;  P52840, ST1A1_MOUSE;  P17988, ST1A1_RAT  ;
DR   P50226, ST1A2_HUMAN;  P50224, ST1A3_HUMAN;  P82609, SULT_ICTPU ;
//
ID   2.8.2.2
DE   Alcohol sulfotransferase.
AN   Hydroxysteroid sulfotransferase.
CA   3'-phosphoadenylyl sulfate + an alcohol = adenosine 3',5'-bisphosphate +
CA   an alkyl sulfate.
CC   -!- Primary and secondary alcohols, including aliphatic alcohols,
CC       ascorbate, chloramphenicol, ephedrine and hydroxysteroids, but not
CC       phenolic steroids, can act as acceptors (cf. EC 2.8.2.15).
DR   Q6IMI6, ST1C3_HUMAN;  P22789, ST2A2_RAT  ;  O00204, ST2B1_HUMAN;
DR   O35400, ST2B1_MOUSE;  Q29YR5, ST2B1_RAT  ;  P07631, SUH2_RAT   ;
DR   P50235, SUH3_RAT   ;  P50234, SUHA_CAVPO ;  P52841, SUHB_CAVPO ;
//
ID   2.8.2.3
DE   Amine sulfotransferase.
AN   Amine N-sulfotransferase.
AN   Arylamine sulfotransferase.
CA   3'-phosphoadenylyl sulfate + an amine = adenosine 3',5'-bisphosphate +
CA   a sulfamate.
CC   -!- A large number of primary and secondary amines can act as acceptors,
CC       including aniline, 2-naphthylamine, cyclohexylamine and octylamine.
DR   O35403, ST3A1_MOUSE;  O46640, ST3A1_RABIT;
//
ID   2.8.2.4
DE   Estrone sulfotransferase.
CA   3'-phosphoadenylyl sulfate + estrone = adenosine 3',5'-bisphosphate +
CA   estrone 3-sulfate.
DR   P19217, ST1E1_BOVIN;  P49887, ST1E1_CAVPO;  P49888, ST1E1_HUMAN;
DR   P49891, ST1E1_MOUSE;  P52844, ST1E1_RAT  ;  P52845, ST1E2_RAT  ;
DR   P49889, ST1E3_RAT  ;  P49890, ST1E6_RAT  ;
//
ID   2.8.2.5
DE   Chondroitin 4-sulfotransferase.
CA   3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate +
CA   chondroitin 4'-sulfate.
CC   -!- The sulfation is at the 4-position of N-acetylgalactosamine residues
CC       of chondroitin.
CC   -!- Not identical with EC 2.8.2.17.
DR   Q7T3S3, CHSTB_DANRE;  Q9NPF2, CHSTB_HUMAN;  Q9JME2, CHSTB_MOUSE;
DR   P69478, CHSTB_RAT  ;  Q9NRB3, CHSTC_HUMAN;  Q99LL3, CHSTC_MOUSE;
DR   Q5XHM7, CHSTC_XENLA;  Q8NET6, CHSTD_HUMAN;
//
ID   2.8.2.6
DE   Choline sulfotransferase.
CA   3'-phosphoadenylyl sulfate + choline = adenosine 3',5'-bisphosphate +
CA   choline sulfate.
//
ID   2.8.2.7
DE   UDP-N-acetylgalactosamine-4-sulfate sulfotransferase.
CA   3'-phosphoadenylyl sulfate + UDP-N-acetyl-D-galactosamine 4-sulfate =
CA   adenosine 3',5'-bisphosphate + UDP-N-acetyl-D-galactosamine 4,6-
CA   bissulfate.
//
ID   2.8.2.8
DE   [Heparan sulfate]-glucosamine N-sulfotransferase.
AN   3'-phosphoadenylyl-sulfate:heparitin N-sulfotransferase.
AN   3'-phosphoadenylyl-sulfate:N-desulfoheparin N-sulfotransferase.
AN   3'-phosphoadenylylsulfate:N-desulfoheparin sulfotransferase.
AN   Desulfoheparin sulfotransferase.
AN   Glucosaminyl N-deacetylase/N-sulfotransferase.
AN   Heparan sulfate 2-N-sulfotransferase.
AN   Heparan sulfate N-deacetylase/N-sulfotransferase.
AN   Heparan sulfate N-sulfotransferase.
AN   Heparan sulfate sulfotransferase.
AN   Heparin N-sulfotransferase.
AN   Heparitin sulfotransferase.
AN   N-desulfoheparin sulfotransferase.
AN   N-heparan sulfate sulfotransferase.
AN   N-HSST.
AN   PAPS:DSH sulfotransferase.
AN   PAPS:N-desulfoheparin sulfotransferase.
CA   3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine
CA   3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine.
CC   -!- The enzyme also catalyzes the sulfation of chondroitin 4-sulfate and
CC       dermatan sulfate, but to a much more limited extent.
CC   -!- Formerly EC 2.8.2.12.
DR   P52848, NDST1_HUMAN;  Q3UHN9, NDST1_MOUSE;  Q02353, NDST1_RAT  ;
DR   Q6GQK9, NDST1_XENLA;  Q5U4X8, NDST1_XENTR;  O97583, NDST2_BOVIN;
DR   P52849, NDST2_HUMAN;  P52850, NDST2_MOUSE;  O95803, NDST3_HUMAN;
DR   Q9EQH7, NDST3_MOUSE;  Q9H3R1, NDST4_HUMAN;  Q9EQW8, NDST4_MOUSE;
DR   Q60V90, NDST_CAEBR ;  Q966W3, NDST_CAEEL ;  Q9V3L1, NDST_DROME ;
//
ID   2.8.2.9
DE   Tyrosine-ester sulfotransferase.
CA   3'-phosphoadenylyl sulfate + L-tyrosine methyl ester = adenosine
CA   3',5'-bisphosphate + L-tyrosine methyl ester 4-sulfate.
CC   -!- Phenols and organic hydroxylamines can act as acceptors (cf.
CC       EC 2.8.2.1).
//
ID   2.8.2.10
DE   Renilla-luciferin sulfotransferase.
AN   Luciferin sulfotransferase.
CA   3'-phosphoadenylyl sulfate + Renilla luciferin = adenosine
CA   3',5'-bisphosphate + luciferyl sulfate.
CC   -!- The product may be identical with Watasenia luciferin.
//
ID   2.8.2.11
DE   Galactosylceramide sulfotransferase.
CA   3'-phosphoadenylyl sulfate + a galactosylceramide = adenosine
CA   3',5'-bisphosphate + a galactosylceramidesulfate.
CC   -!- Also acts on lactosylceramide and monogalactosylalkylacylglycerol.
DR   A6QNK1, G3ST1_BOVIN;  Q99999, G3ST1_HUMAN;  Q9JHE4, G3ST1_MOUSE;
//
ID   2.8.2.12
DE   Transferred entry: 2.8.2.8.
//
ID   2.8.2.13
DE   Psychosine sulfotransferase.
CA   3'-phosphoadenylyl sulfate + galactosylsphingosine = adenosine
CA   3',5'-bisphosphate + psychosine sulfate.
//
ID   2.8.2.14
DE   Bile-salt sulfotransferase.
AN   BAST I.
AN   Bile acid sulfotransferase I.
AN   Bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase.
AN   Bile salt:3'phosphoadenosine-5'-phosphosulfate:sulfotransferase.
AN   Glycolithocholate sulfotransferase.
CA   (1) 3'-phosphoadenylyl sulfate + glycolithocholate = adenosine
CA   3',5'-bisphosphate + glycolithocholate 3-sulfate.
CA   (2) 3'-phosphoadenylyl sulfate + taurolithocholate = adenosine
CA   3',5'-bisphosphate + taurolithocholate sulfate.
CC   -!- The formation of sulfate esters of bile acids is an essential step in
CC       the prevention of toxicity by monohydroxy bile acids in many species.
CC   -!- This enzyme is both a bile salt and a 3-hydroxysteroid
CC       sulfotransferase.
CC   -!- In addition to the 5-beta-bile acid glycolithocholate, deoxycholate,
CC       3-beta-hydroxy-5-cholenoate and dehydroepiandrosterone (3-beta-
CC       hydroxyandrost-5-en-17-one) also act as substrates (see also
CC       EC 2.8.2.2 and EC 2.8.2.34).
CC   -!- May be identical to EC 2.8.2.2.
DR   Q06520, ST2A1_HUMAN;  P52842, ST2A1_MACFA;  P52843, ST2A1_MOUSE;
DR   P15709, ST2A1_RAT  ;  P50236, ST2A2_MOUSE;
//
ID   2.8.2.15
DE   Steroid sulfotransferase.
CA   3'-phosphoadenylyl sulfate + a phenolic steroid = adenosine
CA   3',5'-bisphosphate + steroid O-sulfate.
CC   -!- Broad specificity resembling EC 2.8.2.2, but also acts on estrone.
//
ID   2.8.2.16
DE   Thiol sulfotransferase.
CA   3'-phosphoadenylyl sulfate + a thiol = adenosine 3',5'-bisphosphate +
CA   an S-alkyl thiosulfate.
CC   -!- Also acts on dithiols; substrates include glutathione,
CC       dithioerythritol and 2,3-mercaptopropanol.
//
ID   2.8.2.17
DE   Chondroitin 6-sulfotransferase.
CA   3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate +
CA   chondroitin 6'-sulfate.
CC   -!- The sulfation is at the 6-position of N-acetylgalactosamine residues
CC       of chondroitin.
CC   -!- Not identical with EC 2.8.2.5.
DR   Q92179, CHST3_CHICK;  Q7LGC8, CHST3_HUMAN;  O88199, CHST3_MOUSE;
DR   Q9QZL2, CHST3_RAT  ;  O93403, CHST3_TORCA;  Q9NS84, CHST7_HUMAN;
DR   Q9EP78, CHST7_MOUSE;  Q6XQG8, CHST7_RAT  ;
//
ID   2.8.2.18
DE   Cortisol sulfotransferase.
AN   Glucocorticosteroid sulfotransferase.
CA   3'-phosphoadenylyl sulfate + cortisol = adenosine 3',5'-bisphosphate +
CA   cortisol 21-sulfate.
//
ID   2.8.2.19
DE   Triglucosylalkylacylglycerol sulfotransferase.
CA   3'-phosphoadenylyl sulfate + alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-
CA   (1->6)-alpha-D-glucosyl-(1->3)-1-O-alkyl-2-O-acylglycerol = adenosine
CA   3',5'-bisphosphate + 6-sulfo-alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-
CA   (1->6)-alpha-D-glucosyl-(1->3)-1-O-alkyl-2-O-acylglycerol.
//
ID   2.8.2.20
DE   Protein-tyrosine sulfotransferase.
AN   Tyrosylprotein sulfotransferase.
CA   3'-phosphoadenylyl sulfate + protein tyrosine = adenosine
CA   3',5'-bisphosphate + protein tyrosine-O-sulfate.
CC   -!- The tyrosine residues of some specific proteins of rat
CC       pheochromocytoma cells act as acceptors.
DR   Q9PTE6, TPST1_DANRE;  O60507, TPST1_HUMAN;  O70281, TPST1_MOUSE;
DR   Q3KR92, TPST1_RAT  ;  Q3SYY2, TPST2_BOVIN;  Q5ZJI0, TPST2_CHICK;
DR   O60704, TPST2_HUMAN;  Q4R863, TPST2_MACFA;  O88856, TPST2_MOUSE;
DR   Q5RJS8, TPST2_RAT  ;  O77081, TPSTA_CAEEL;  A8XLL3, TPSTB_CAEBR;
DR   Q20351, TPSTB_CAEEL;  Q3EDG5, TPST_ARATH ;  Q9VYB7, TPST_DROME ;
//
ID   2.8.2.21
DE   Keratan sulfotransferase.
CA   3'-phosphoadenylyl sulfate + keratan = adenosine 3',5'-bisphosphate +
CA   keratan 6'-sulfate.
CC   -!- Sulfation takes place at the 6-position of galactosyl and
CC       N-acetylglucosaminyl residues in keratan, a proteoglycan.
CC   -!- Not identical with EC 2.8.2.5, EC 2.8.2.6 or EC 2.8.2.17.
DR   Q6DBY9, CHST1_DANRE;  O43916, CHST1_HUMAN;  Q9EQC0, CHST1_MOUSE;
DR   Q5RJQ0, CHST1_RAT  ;
//
ID   2.8.2.22
DE   Aryl-sulfate sulfotransferase.
AN   Arylsulfate sulfotransferase.
CA   An aryl sulfate + a phenol = a phenol + an aryl sulfate.
CC   -!- Hydroxy groups of tyrosine residues in peptides such as angiotensin
CC       can act as acceptors.
CC   -!- Does not act on 3'-phosphoadenylyl sulfate or adenosine
CC       3',5'-bisphosphate.
//
ID   2.8.2.23
DE   [Heparan sulfate]-glucosamine 3-sulfotransferase 1.
AN   3'-phosphoadenylyl-sulfate:heparin-glucosamine 3-O-sulfotransferase.
AN   3-OST-1.
AN   Glucosaminyl 3-O-sulfotransferase.
AN   Heparan sulfate D-glucosaminyl 3-O-sulfotransferase.
AN   Heparin-glucosamine 3-O-sulfotransferase.
CA   3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine
CA   3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate.
CC   -!- This enzyme differs from EC 2.8.2.29 and EC 2.8.2.30 by being the
CC       most selective for a precursor of the antithrombin-binding site.
CC   -!- It has a minimal acceptor sequence of: -> GlcNAc6S->GlcA->
CC       GlcN2S*+-6S->IdoA2S->GlcN2S->.
CC   -!- It can also modify other precursor sequences within heparan sulfate
CC       but this action does not create functional antithrombin-binding
CC       sites.
CC   -!- These precursors are variants of the consensus sequence: ->
CC       Glc(N2S>NAc)+-6S->GlcA->GlcN2S*+-6S->GlcA>IdoA+-2S->
CC       Glc(N2S/NAc)+-6S->.
CC   -!- If the heparan sulfate substrate lacks 2-O-sulfation of GlcA
CC       residues, then enzyme specificity is expanded to modify selected
CC       glucosamine residues preceded by IdoA as well as GlcA.
DR   O14792, HS3S1_HUMAN;  O35310, HS3S1_MOUSE;  Q9ESG5, HS3S1_RAT  ;
DR   Q9Y661, HS3S4_HUMAN;  Q8IZT8, HS3S5_HUMAN;  Q8BSL4, HS3S5_MOUSE;
DR   Q96QI5, HS3S6_HUMAN;  Q5GFD5, HS3S6_MOUSE;  Q8BKN6, HS3SA_MOUSE;
//
ID   2.8.2.24
DE   Desulfoglucosinolate sulfotransferase.
CA   3'-phosphoadenylyl sulfate + desulfoglucotropeolin = adenosine
CA   3',5'-bisphosphate + glucotropeolin.
CC   -!- Involved with EC 2.4.1.195 in the biosynthesis of thioglycosides in
CC       cruciferous plants.
//
ID   2.8.2.25
DE   Flavonol 3-sulfotransferase.
CA   3'-phosphoadenylyl sulfate + quercetin = adenosine 3',5'-bisphosphate +
CA   quercetin 3-sulfate.
CC   -!- Also acts on some other flavonol aglycones.
//
ID   2.8.2.26
DE   Quercetin-3-sulfate 3'-sulfotransferase.
CA   3'-phosphoadenylyl sulfate + quercetin 3-sulfate = adenosine
CA   3',5'-bisphosphate + quercetin 3,3'-bissulfate.
//
ID   2.8.2.27
DE   Quercetin-3-sulfate 4'-sulfotransferase.
CA   3'-phosphoadenylyl sulfate + quercetin 3-sulfate = adenosine
CA   3',5'-bisphosphate + quercetin 3,4'-bissulfate.
//
ID   2.8.2.28
DE   Quercetin-3,3'-bissulfate 7-sulfotransferase.
CA   3'-phosphoadenylyl sulfate + quercetin 3,3'-bissulfate = adenosine
CA   3',5'-bisphosphate + quercetin 3,3',7-trissulfate.
CC   -!- Quercetin 3,4'-bissulfate can also act as acceptor.
//
ID   2.8.2.29
DE   [Heparan sulfate]-glucosamine 3-sulfotransferase 2.
AN   3-OST-2.
AN   Glucosaminyl 3-O-sulfotransferase 2.
AN   Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2.
CA   3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine
CA   3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate.
CC   -!- This enzyme sulfates the residues marked with an asterisk in
CC       sequences containing at least ->IdoA2S->GlcN*-> or ->GlcA2S->GlcN*->.
CC   -!- Preference for GlcN2S versus unmodified GlcN has not yet been
CC       established.
CC   -!- Additional structural features are presumably required for substrate
CC       recognition, since the 3-O-sulfated residue is of low abundance,
CC       whereas the above IdoA-containing sequence is quite abundant.
CC   -!- This enzyme differs from the other [heparan sulfate]-glucosamine
CC       3-sulfotransferases by modifying selected glucosamine residues
CC       preceded by GlcA2S; EC 2.8.2.23 prefers GlcA or IdoA, whereas
CC       EC 2.8.2.30 prefers IdoA2S.
DR   Q9Y278, HS3S2_HUMAN;  Q673U1, HS3S2_MOUSE;  Q80W66, HS3S2_RAT  ;
//
ID   2.8.2.30
DE   [Heparan sulfate]-glucosamine 3-sulfotransferase 3.
AN   3-OST-3.
AN   Glucosaminyl 3-O-sulfotransferase 3.
AN   Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3.
CA   3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine
CA   3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate.
CC   -!- Two major substrates contain the tetrasaccharides: -> undetermined
CC       2-sulfo-uronic acid->GlcN2S->IdoA2S->GlcN*-> and -> undetermined
CC       2-sulfo-uronic acid->GlcN2S->IdoA2S->GlcN6S*-> with modification of
CC       the N-unsubstituted glucosamine residue (shown with an asterisk).
CC   -!- Modification of selected sequences containing N-sulfo-glucosamine
CC       residues cannot yet be excluded.
CC   -!- The 3-O-sulfated heparan sulfate can be utilized by Herpes simplex
CC       virus type 1 as an entry receptor to infect the target cells.
CC   -!- There are two isozymes, known as 3-OST-3(A) and 3-OST-3(B), which
CC       have identical catalytic domains but are encoded by different
CC       mammalian genes.
CC   -!- The specificity of this enzyme differs from that of the other
CC       [heparan sulfate]-glucosamine 3-sulfotransferases.
CC   -!- It is inefficient at modifying precursors of the antithrombin binding
CC       site (in contrast to EC 2.8.2.23) and it does not modify glucosamine
CC       preceded by GlcA2S (unlike EC 2.8.2.29).
DR   Q9Y663, HS3SA_HUMAN;  Q9Y662, HS3SB_HUMAN;  Q9QZS6, HS3SB_MOUSE;
//
ID   2.8.2.31
DE   Petromyzonol sulfotransferase.
AN   PZ-SULT.
CA   3'-phosphoadenylyl sulfate + 5-alpha-cholan-3-alpha,7-alpha,12-alpha,24-
CA   tetrol = adenosine 3',5'-bisphosphate + 5-alpha-cholan-3-alpha,7-
CA   alpha,12-alpha-triol 24-sulfate.
CC   -!- The enzyme from the lamprey Petromyzon marinus can also use the
CC       corresponding 3-ketone as a substrate.
CC   -!- It is stereoselective (5-alpha-cholane) and regioselective,
CC       exhibiting a preference for an hydroxy group at C-24.
CC   -!- The enzyme is inactive when allocholic acid, which has a carboxy
CC       group at C-24, is used as a substrate.
//
ID   2.8.2.32
DE   Scymnol sulfotransferase.
CA   3'-phosphoadenosine 5'-phosphosulfate + 5-beta-scymnol = adenosine
CA   3',5'-bisphosphate + 5-beta-scymnol sulfate.
CC   -!- The enzyme from the shark Heterodontus portusjacksoni is able to
CC       sulfate the C(27) bile salts 5-beta-scymnol (the natural bile salt)
CC       and 5-alpha-cyprinol (the carp bile salt).
CC   -!- Enzyme activity is activated by Mg(2+) but inhibited by the product
CC       5-beta-scymnol sulfate.
//
ID   2.8.2.33
DE   N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase.
AN   GalNAc4S-6ST.
CA   (1) 3-phospho-5-adenylyl sulfate + [dermatan]-4-O-sulfo-N-
CA   acetylgalactosamine = adenosine 3',5'-bisphosphate + [dermatan]-4,6-di-O-
CA   sulfo-N-acetyl-D-galactosamine.
CA   (2) 3-phospho-5-adenylyl sulfate + [chondroitin]-4-O-sulfo-N-
CA   acetylgalactosamine = adenosine 3',5'-bisphosphate + [chondroitin]-4,6-
CA   di-O-sulfo-N-acetyl-D-galactosamine.
CC   -!- The enzyme from human transfers sulfate to position 6 of both
CC       internal residues and nonreducing terminal GalNAc 4-sulfate residues
CC       of chondroitin sulfate.
CC   -!- Oligosaccharides derived from chondroitin sulfate also serve as
CC       acceptors but chondroitin sulfate E, keratan sulfate and heparan
CC       sulfate do not.
CC   -!- Differs from EC 2.8.2.17 in being able to use both chondroitin and
CC       dermatan as effective substrates.
DR   Q7LFX5, CHSTF_HUMAN;  Q91XQ5, CHSTF_MOUSE;  Q8WTN9, CHSTF_OMMSL;
DR   Q8CHI9, CHSTF_RAT  ;
//
ID   2.8.2.34
DE   Glycochenodeoxycholate sulfotransferase.
AN   BAST.
AN   Bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase.
AN   Bile acid:PAPS:sulfotransferase.
CA   3'-phosphoadenylyl sulfate + glycochenodeoxycholate = adenosine
CA   3',5'-bisphosphate + glycochenodeoxycholate 7-sulfate.
CC   -!- Specifically sulfates glycochenodeoxycholate at the 7-alpha-position
CC       (see also EC 2.8.2.14).
CC   -!- The monohydroxy bile acids glycolithocholate, chenodeoxycholate and
CC       ursodeoxycholate act as inhibitors.
//
ID   2.8.2.35
DE   Dermatan 4-sulfotransferase.
AN   CHST14 protein.
AN   Dermatan N-acetylgalactosamine 4-O-sulfotransferase.
AN   Dermatan-specific N-acetylgalactosamine 4-O-sulfotransferase.
CA   3'-phospho-5'-adenylyl sulfate + [dermatan]-N-acetyl-D-galactosamine =
CA   adenosine 3',5'-bisphosphate + [dermatan]- 4-O-sulfo-N-acetyl-D-
CA   galactosamine.
CC   -!- The sulfation takes place at the 4-position of N-acetylgalactosamine
CC       residues of dermatan.
CC   -!- D4ST-1 shows a strong preference in vitro for sulfate transfer to
CC       IdoUA-alpha(1,3)GalNAc-beta(1,4) that is flanked by GlcUA-
CC       beta(1,3)GalNAc-beta(1,4) as compared with IdoUA-alpha(1,3)GalNAc-
CC       beta(1,4) flanked by IdoUA-alpha(1,3)GalNAc-beta(1,4).
DR   Q8NCH0, CHSTE_HUMAN;  Q80V53, CHSTE_MOUSE;
//
ID   2.8.3.1
DE   Propionate CoA-transferase.
CA   Acetyl-CoA + propanoate = acetate + propanoyl-CoA.
CC   -!- Butanoate and lactate can also act as acceptors.
//
ID   2.8.3.2
DE   Oxalate CoA-transferase.
AN   Succinyl--beta-ketoacyl-CoA transferase.
CA   Succinyl-CoA + oxalate = succinate + oxalyl-CoA.
//
ID   2.8.3.3
DE   Malonate CoA-transferase.
CA   Acetyl-CoA + malonate = acetate + malonyl-CoA.
CC   -!- The enzyme from Pseudomonas ovalis also catalyzes the reaction of
CC       EC 4.1.1.9.
//
ID   2.8.3.4
DE   Deleted entry.
//
ID   2.8.3.5
DE   3-oxoacid CoA-transferase.
AN   Succinyl-CoA:3-ketoacid-CoA transferase.
CA   Succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA.
CC   -!- Acetoacetate or, more slowly, 3-oxopropanoate, 3-oxopentanoate,
CC       3-oxo-4-methylpentanoate or 3-oxohexanoate can act as acceptor.
CC   -!- Malonyl-CoA can act instead of succinyl-CoA.
PR   PROSITE; PDOC00980;
DR   Q9JJN4, SCO2A_MOUSE;  Q5XIJ9, SCO2A_RAT  ;  Q9ESL0, SCO2B_MOUSE;
DR   P42315, SCOA_BACSU ;  Q9ZLE3, SCOA_HELPJ ;  P56006, SCOA_HELPY ;
DR   P63649, SCOA_MYCBO ;  P63648, SCOA_MYCTU ;  B0RVK4, SCOA_XANCB ;
DR   P0C7I7, SCOA_XANCP ;  P42316, SCOB_BACSU ;  Q9ZLE4, SCOB_HELPJ ;
DR   P56007, SCOB_HELPY ;  P63651, SCOB_MYCBO ;  P63650, SCOB_MYCTU ;
DR   B0RVK3, SCOB_XANCB ;  P0C7I8, SCOB_XANCP ;  P55809, SCOT1_HUMAN;
DR   Q9D0K2, SCOT1_MOUSE;  Q29551, SCOT1_PIG  ;  B2GV06, SCOT1_RAT  ;
DR   Q9BYC2, SCOT2_HUMAN;  Q09450, SCOT_CAEEL ;  Q54JD9, SCOT_DICDI ;
//
ID   2.8.3.6
DE   3-oxoadipate CoA-transferase.
AN   Beta-ketoadipate:succinyl-CoA transferase.
CA   Succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA.
PR   PROSITE; PDOC00980;
DR   Q8VPF3, CATI_PSESB ;  Q8VPF2, CATJ_PSESB ;  Q43973, PCAI_ACIAD ;
DR   Q01103, PCAI_PSEPU ;  Q59091, PCAJ_ACIAD ;  P0A101, PCAJ_PSEPK ;
DR   P0A102, PCAJ_PSEPU ;
//
ID   2.8.3.7
DE   Succinate--citramalate CoA-transferase.
AN   Citramalate CoA-transferase.
AN   Itaconate CoA-transferase.
CA   Succinyl-CoA + citramalate = succinate + citramalyl-CoA.
CC   -!- Itaconate can also act as acceptor.
//
ID   2.8.3.8
DE   Acetate CoA-transferase.
CA   Acyl-CoA + acetate = a fatty acid anion + acetyl-CoA.
CC   -!- Acts on butanoyl-CoA and pentanoyl-CoA.
PR   PROSITE; PDOC00980;
DR   P76459, ATOA_ECOLI ;  P44874, ATOA_HAEIN ;  P76458, ATOD_ECOLI ;
DR   P44875, ATOD_HAEIN ;
//
ID   2.8.3.9
DE   Butyrate--acetoacetate CoA-transferase.
CA   Butanoyl-CoA + acetoacetate = butanoate + acetoacetyl-CoA.
CC   -!- Butanoate, acetoacetate and their CoA thioesters are the preferred
CC       substrates, but the enzyme also acts, more slowly, on the derivatives
CC       of a number of C(2) to C(6) monocarboxylic acids.
PR   PROSITE; PDOC00980;
DR   P33752, CTFA_CLOAB ;  P23673, CTFB_CLOAB ;
//
ID   2.8.3.10
DE   Citrate CoA-transferase.
CA   Acetyl-CoA + citrate = acetate + (3S)-citryl-CoA.
CC   -!- Component of EC 4.1.3.6.
CC   -!- Also catalyzes the transfer of thioacyl carrier protein from its
CC       acetyl thioester to citrate.
DR   P75726, CILA_ECOLI ;  P44459, CILA_HAEIN ;  P45413, CILA_KLEPN ;
DR   O53079, CILA_LEUMC ;
//
ID   2.8.3.11
DE   Citramalate CoA-transferase.
CA   Acetyl-CoA + citramalate = acetate + (3S)-citramalyl-CoA.
CC   -!- Component of EC 4.1.3.22.
CC   -!- Also catalyzes the transfer of thioacyl carrier protein from its
CC       acetyl thioester to citramalate.
//
ID   2.8.3.12
DE   Glutaconate CoA-transferase.
CA   Acetyl-CoA + (E)-glutaconate = acetate + glutaconyl-1-CoA.
CC   -!- Glutarate, (R)-2-hydroxyglutarate, propenoate and propanoate, but not
CC       (Z)-glutaconate, can also act as acceptors.
DR   Q59111, GCTA_ACIFV ;  Q59112, GCTB_ACIFV ;
//
ID   2.8.3.13
DE   Succinate--hydroxymethylglutarate CoA-transferase.
CA   Succinyl-CoA + 3-hydroxy-3-methylglutarate = succinate + (S)-3-hydroxy-3-
CA   methylglutaryl-CoA.
CC   -!- Malonyl-CoA can also act as donor, more slowly.
//
ID   2.8.3.14
DE   5-hydroxypentanoate CoA-transferase.
AN   5-hydroxyvalerate CoA-transferase.
CA   Acetyl-CoA + 5-hydroxypentanoate = acetate + 5-hydroxypentanoyl-CoA.
CC   -!- Propanoyl-CoA, acetyl-CoA, butanoyl-CoA and some other acyl-CoAs can
CC       act as substrates, more slowly than 5-hydroxypentanoyl-CoA.
//
ID   2.8.3.15
DE   Succinyl-CoA:(R)-benzylsuccinate CoA-transferase.
AN   Benzylsuccinate CoA-transferase.
CA   Succinyl-CoA + (R)-2-benzylsuccinate = succinate + (R)-2-benzylsuccinyl-
CA   CoA.
CC   -!- Involved in anaerobic catabolism of toluene and is a strictly
CC       toluene-induced enzyme that catalyzes the reversible regio- and
CC       enantio-selective synthesis of (R)-2-benzylsuccinyl-CoA.
CC   -!- The enzyme from Thauera aromatica is inactive when (R)-
CC       benzylsuccinate is replaced by (S)-benzylsuccinate.
//
ID   2.8.3.16
DE   Formyl-CoA transferase.
AN   Formyl-CoA oxalate CoA-transferase.
AN   Formyl-coenzyme A transferase.
CA   Formyl-CoA + oxalate = formate + oxalyl-CoA.
CC   -!- The enzyme from Oxalobacter formigenes can also catalyze the transfer
CC       of CoA from formyl-CoA to succinate.
DR   Q89QH2, FCTA_BRAJA ;  A5EGD7, FCTA_BRASB ;  A4YXN2, FCTA_BRASO ;
DR   A7ZPI2, FCTA_ECO24 ;  B7UG84, FCTA_ECO27 ;  B7MH34, FCTA_ECO45 ;
DR   B7LBS7, FCTA_ECO55 ;  Q8XBR7, FCTA_ECO57 ;  B5YYX4, FCTA_ECO5E ;
DR   B7NPQ8, FCTA_ECO7I ;  B7MY33, FCTA_ECO81 ;  B7M6P3, FCTA_ECO8A ;
DR   C4ZVR1, FCTA_ECOBW ;  B1X9P6, FCTA_ECODH ;  A8A2M8, FCTA_ECOHS ;
DR   A1ADQ1, FCTA_ECOK1 ;  Q0TF87, FCTA_ECOL5 ;  Q8FFE8, FCTA_ECOL6 ;
DR   B1IX88, FCTA_ECOLC ;  P69902, FCTA_ECOLI ;  B7N5X4, FCTA_ECOLU ;
DR   B6I6S5, FCTA_ECOSE ;  B1LMH0, FCTA_ECOSM ;  Q1R8Z2, FCTA_ECOUT ;
DR   B6JE29, FCTA_OLICO ;  O06644, FCTA_OXAFO ;  Q2IUI7, FCTA_RHOP2 ;
DR   Q07Q82, FCTA_RHOP5 ;  Q6N8F8, FCTA_RHOPA ;  Q217M3, FCTA_RHOPB ;
DR   Q139H7, FCTA_RHOPS ;  B3QBS6, FCTA_RHOPT ;  B2TWX3, FCTA_SHIB3 ;
DR   Q31Y97, FCTA_SHIBS ;  Q32DG9, FCTA_SHIDS ;  Q0T2C3, FCTA_SHIF8 ;
DR   P69903, FCTA_SHIFL ;  Q3YZF6, FCTA_SHISS ;  Q82M40, FCTA_STRAW ;
DR   O87838, FCTA_STRCO ;
//
ID   2.8.3.17
DE   Cinnamoyl-CoA:phenyllactate CoA-transferase.
AN   FldA.
CA   (E)-cinnamoyl-CoA + (R)-phenyllactate = (E)-cinnamate + (R)-phenyllactyl-
CA   CoA.
CC   -!- 3-phenylpropranoate is a better CoA acceptor than (R)-phenyllactate
CC       in vitro.
CC   -!- The enzyme from Clostridium sporogenes is specific for derivatives of
CC       3-phenylpropanoate and 4-phenylbutyrate.
//
ID   2.8.4.1
DE   Coenzyme-B sulfoethylthiotransferase.
AN   Methyl coenzyme M reductase.
AN   Methyl-CoM reductase.
CA   Methyl-CoM + coenzyme B = CoM-S-S-CoB + methane.
CF   Coenzyme F430.
CC   -!- Highly specific for coenzyme B with a heptanoyl chain; ethyl CoM and
CC       difluoromethyl CoM are poor substrates.
CC   -!- The sulfide sulfur can be replaced by selenium but not by oxygen.
CC   -!- The enzyme can also function in reverse, for anaerobic oxidation of
CC       methane.
DR   P07962, MCRA_METBF ;  P12971, MCRA_METFE ;  Q58256, MCRA_METJA ;
DR   Q49605, MCRA_METKA ;  P22948, MCRA_METTE ;  O27232, MCRA_METTH ;
DR   P11558, MCRA_METTM ;  P07961, MCRA_METVA ;  P11559, MCRA_METVO ;
DR   P07955, MCRB_METBF ;  P12972, MCRB_METFE ;  Q58252, MCRB_METJA ;
DR   P22949, MCRB_METTE ;  O27236, MCRB_METTH ;  P11560, MCRB_METTM ;
DR   P07956, MCRB_METVA ;  P11561, MCRB_METVO ;  P07964, MCRG_METBF ;
DR   P12973, MCRG_METFE ;  Q58255, MCRG_METJA ;  P22950, MCRG_METTE ;
DR   O27233, MCRG_METTH ;  P11562, MCRG_METTM ;  P07963, MCRG_METVA ;
DR   P11563, MCRG_METVO ;  Q49174, MCRX_METFV ;  Q60391, MCRX_METJA ;
DR   P21110, MCRX_METTH ;  P58815, MCRX_METTM ;  Q49171, MCRY_METFV ;
DR   Q60390, MCRY_METJA ;  P21111, MCRY_METTH ;  Q49173, MCRZ_METFV ;
DR   Q60387, MCRZ_METJA ;  P21112, MCRZ_METTH ;  P58816, MCRZ_METTM ;
//
ID   2.8.4.2
DE   Arsenate-mycothiol transferase.
CA   Arsenate + mycothiol = arseno-mycothiol + H(2)O.
CC   -!- Reduction of arsenate is part of a defense mechanism of the cell
CC       against toxic arsenate.
CC   -!- The product arseno-mycothiol is reduced by EC 1.20.4.3 (mycoredoxin)
CC       to arsenite and mycothiol-mycoredoxin disulfide.
CC   -!- Finally, a second mycothiol recycles mycoredoxin and forms
CC       mycothione.
//
ID   2.9.1.1
DE   L-seryl-tRNA(Sec) selenium transferase.
AN   Cysteinyl-tRNA(Sec)-selenium transferase.
AN   Cysteinyl-tRNA(Sel)-selenium transferase.
AN   L-selenocysteinyl-tRNA(Sec) synthase.
AN   L-selenocysteinyl-tRNA(Sel) synthase.
AN   Selenocysteine synthase.
CA   L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) +
CA   phosphate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Recognizes specifically tRNA(Sec)-species.
CC   -!- Binding of tRNA(Sec) also occurs in the absence of the seryl group.
CC   -!- 2-aminoacryloyl-tRNA, bound to the enzyme as an imine with the
CC       pyridoxal phosphate, is an intermediate in the reaction.
CC   -!- Since the selenium atom replaces oxygen in serine, the product may
CC       also be referred to as L-selenoseryl-tRNA(Sel).
CC   -!- The abbreviation Sel has also been used for selenocysteine but Sec is
CC       preferred.
DR   A3N2L0, SELA_ACTP2 ;  B3GYP5, SELA_ACTP7 ;  A6TQL2, SELA_ALKMQ ;
DR   A8MHJ4, SELA_ALKOO ;  O67140, SELA_AQUAE ;  A8EV04, SELA_ARCB4 ;
DR   A7ZBQ0, SELA_CAMC1 ;  A0RR46, SELA_CAMFF ;  A8FN57, SELA_CAMJ8 ;
DR   A7H1W2, SELA_CAMJD ;  Q9PMS2, SELA_CAMJE ;  A1W0Z5, SELA_CAMJJ ;
DR   Q5HT33, SELA_CAMJR ;  B9KDG5, SELA_CAMLR ;  Q3AB61, SELA_CARHZ ;
DR   A7FXT6, SELA_CLOB1 ;  C3L3I3, SELA_CLOB6 ;  A5I656, SELA_CLOBH ;
DR   C1FVV5, SELA_CLOBJ ;  B1ILX5, SELA_CLOBK ;  A7GHJ2, SELA_CLOBL ;
DR   B1KZQ3, SELA_CLOBM ;  Q0TNJ4, SELA_CLOP1 ;  Q8XIK2, SELA_CLOPE ;
DR   Q0SR63, SELA_CLOPS ;  C6BW42, SELA_DESAD ;  B1I3P6, SELA_DESAP ;
DR   P56372, SELA_DESBA ;  B8J1N0, SELA_DESDA ;  C4XIH0, SELA_DESMR ;
DR   Q6AMK5, SELA_DESPS ;  P61735, SELA_DESVH ;  A7ZTD9, SELA_ECO24 ;
DR   B7ULF0, SELA_ECO27 ;  B7MFF5, SELA_ECO45 ;  B7L708, SELA_ECO55 ;
DR   P0A822, SELA_ECO57 ;  B5YW91, SELA_ECO5E ;  B7NP97, SELA_ECO7I ;
DR   B7N237, SELA_ECO81 ;  B7M3L6, SELA_ECO8A ;  C4ZXI2, SELA_ECOBW ;
DR   A8A651, SELA_ECOHS ;  A1AHD0, SELA_ECOK1 ;  Q0TBL4, SELA_ECOL5 ;
DR   Q8FCC1, SELA_ECOL6 ;  B1IZK2, SELA_ECOLC ;  P0A821, SELA_ECOLI ;
DR   B7NEP6, SELA_ECOLU ;  B6I3G5, SELA_ECOSE ;  B1LK21, SELA_ECOSM ;
DR   Q1R503, SELA_ECOUT ;  C5BC01, SELA_EDWI9 ;  B7LTJ8, SELA_ESCF3 ;
DR   Q9S3K3, SELA_EUBAC ;  Q39ZL4, SELA_GEOMG ;  B9LZW4, SELA_GEOSF ;
DR   P61736, SELA_GEOSL ;  A5G937, SELA_GEOUR ;  Q7VKC2, SELA_HAEDU ;
DR   Q4QML1, SELA_HAEI8 ;  A5UE18, SELA_HAEIE ;  P43910, SELA_HAEIN ;
DR   B8F738, SELA_HAEPS ;  Q7VI68, SELA_HELHP ;  B6JP11, SELA_HELP2 ;
DR   Q9ZJA7, SELA_HELPJ ;  O26043, SELA_HELPY ;  Q0BZB0, SELA_HYPNA ;
DR   B5XMW1, SELA_KLEP3 ;  A6TFJ1, SELA_KLEP7 ;  Q65Q15, SELA_MANSM ;
DR   B8ES25, SELA_METSB ;  Q2RFK3, SELA_MOOTA ;  O33277, SELA_MOOTH ;
DR   B9L5S9, SELA_NAUPA ;  A1AYS1, SELA_PARDP ;  Q9CK66, SELA_PASMU ;
DR   Q7MY02, SELA_PHOLL ;  B4F0S0, SELA_PROMH ;  A6VCR3, SELA_PSEA7 ;
DR   B7V1L9, SELA_PSEA8 ;  Q02FL3, SELA_PSEAB ;  Q9HV01, SELA_PSEAE ;
DR   Q1IFP3, SELA_PSEE4 ;  A5VXT7, SELA_PSEP1 ;  B0KKB9, SELA_PSEPG ;
DR   Q88QJ8, SELA_PSEPK ;  B1J347, SELA_PSEPW ;  A4VFW8, SELA_PSEU5 ;
DR   P58226, SELA_RHIME ;  B5EX94, SELA_SALA4 ;  A9MLE0, SELA_SALAR ;
DR   Q57IE9, SELA_SALCH ;  B5FLG0, SELA_SALDC ;  B5R5B6, SELA_SALEP ;
DR   B5RGJ4, SELA_SALG2 ;  B4T974, SELA_SALHS ;  B4SWN1, SELA_SALNS ;
DR   Q5PLQ2, SELA_SALPA ;  A9MVI1, SELA_SALPB ;  C0Q1E4, SELA_SALPC ;
DR   B5BHW8, SELA_SALPK ;  B4TZT5, SELA_SALSV ;  Q8Z2D8, SELA_SALTI ;
DR   Q8ZL69, SELA_SALTY ;  A8G7W0, SELA_SERP5 ;  Q8EKI8, SELA_SHEON ;
DR   B2U5A3, SELA_SHIB3 ;  Q31V36, SELA_SHIBS ;  Q328Y9, SELA_SHIDS ;
DR   Q0SYB5, SELA_SHIF8 ;  Q83J28, SELA_SHIFL ;  Q3YVV3, SELA_SHISS ;
DR   Q30SC1, SELA_SULDN ;  Q8R8W4, SELA_THETN ;  Q7M9L1, SELA_WOLSU ;
DR   A1JT25, SELA_YERE8 ;  A7FP80, SELA_YERP3 ;  Q1C3H9, SELA_YERPA ;
DR   B2K7H8, SELA_YERPB ;  Q8Z9Y1, SELA_YERPE ;  A9R4E4, SELA_YERPG ;
DR   Q1CDA2, SELA_YERPN ;  A4TGQ3, SELA_YERPP ;  Q663U3, SELA_YERPS ;
DR   B1JH26, SELA_YERPY ;
//
ID   2.9.1.2
DE   O-phospho-L-seryl-tRNA(Sec):L-selenocysteinyl-tRNA synthase.
AN   O-phosphoseryl-tRNA(Sec) selenium transferase.
AN   O-phosphoseryl-tRNA:selenocysteinyl-tRNA synthase.
AN   SepSecS.
CA   O-phospho-L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-
CA   tRNA(Sec) + phosphate.
CF   Pyridoxal 5'-phosphate.
CC   -!- In archaea and eukarya selenocysteine formation is achieved by a two-
CC       step process: EC 2.7.1.164 phosphorylates the endogenous L-seryl-
CC       tRNA(Sec) to O-phospho-L-seryl-tRNA(Sec), and then this misacylated
CC       amino acid-tRNA species is converted to L-selenocysteinyl-tRNA(Sec)
CC       by Sep-tRNA:Sec-tRNA synthase.
CC   -!- Formerly EC 2.9.1.n1.
DR   Q61JN8, SPCS_CAEBR ;  Q18953, SPCS_CAEEL ;  Q803A7, SPCS_DANRE ;
DR   Q54VQ6, SPCS_DICDI ;  Q9HD40, SPCS_HUMAN ;  Q58027, SPCS_METJA ;
DR   Q8TXK0, SPCS_METKA ;  Q6LZM9, SPCS_METMP ;  Q6P6M7, SPCS_MOUSE ;
DR   Q5RAK7, SPCS_PONAB ;  Q28EN2, SPCS_XENTR ;
//
ID   2.9.1.n1
DE   Transferred entry: 2.9.1.2.
//
ID   3.1.1.1
DE   Carboxylesterase.
AN   Ali-esterase.
AN   B-esterase.
AN   Cocaine esterase.
AN   Methylbutyrase.
AN   Monobutyrase.
AN   Procaine esterase.
CA   A carboxylic ester + H(2)O = an alcohol + a carboxylate.
CC   -!- Wide specificity; also hydrolyzes vitamin A esters.
CC   -!- The enzymes from microsomes also catalyze the reactions of
CC       EC 3.1.1.2, EC 3.1.1.5, EC 3.1.1.6, EC 3.1.1.23, EC 3.1.1.28,
CC       EC 3.1.2.2, EC 3.5.1.4, and EC 3.5.1.13.
PR   PROSITE; PDOC00112;
DR   B3PI89, BIOHC_CELJU;  Q8VCT4, CES3_MOUSE ;  P16303, CES3_RAT   ;
DR   Q9LK21, CXE11_ARATH;  Q9SMN0, CXE12_ARATH;  Q9SMM9, CXE13_ARATH;
DR   Q9FG13, CXE15_ARATH;  Q8LED9, CXE16_ARATH;  Q9LFR7, CXE17_ARATH;
DR   Q9LT10, CXE18_ARATH;  Q0ZPV7, CXE1_ACTER ;  Q9LMA7, CXE1_ARATH ;
DR   Q9LVB8, CXE20_ARATH;  Q9SX78, CXE2_ARATH ;  Q9FX92, CXE3_ARATH ;
DR   Q9FX93, CXE4_ARATH ;  Q9FX94, CXE5_ARATH ;  Q9SX25, CXE6_ARATH ;
DR   Q9ZQ91, CXE7_ARATH ;  O64640, CXE8_ARATH ;  O64641, CXE9_ARATH ;
DR   Q8VCU1, ES31L_MOUSE;  Q04456, EST1_CAEBR ;  Q04457, EST1_CAEEL ;
DR   P16854, EST1_CULPI ;  P23141, EST1_HUMAN ;  O46421, EST1_MACFA ;
DR   Q64419, EST1_MESAU ;  Q8VCC2, EST1_MOUSE ;  Q29550, EST1_PIG   ;
DR   Q51758, EST1_PSEFL ;  P12337, EST1_RABIT ;  P81429, EST1_SCHGA ;
DR   P86325, EST1_THEFU ;  Q47M62, EST1_THEFY ;  Q64176, EST22_MOUSE;
DR   Q07085, EST2_CAEEL ;  P21370, EST2_CULPI ;  O00748, EST2_HUMAN ;
DR   Q53547, EST2_PSEFL ;  P14943, EST2_RABIT ;  P10959, EST2_RAT   ;
DR   Q63880, EST31_MOUSE;  Q6UWW8, EST3_HUMAN ;  Q5RCL7, EST3_PONAB ;
DR   Q63108, EST3_RAT   ;  P10094, EST4_DROMO ;  Q64573, EST4_RAT   ;
DR   Q6AW47, EST5A_CANFA;  O16168, EST5A_DROMI;  O16173, EST5A_DROPE;
DR   P25727, EST5A_DROPS;  Q8I034, EST5A_FELCA;  Q6NT32, EST5A_HUMAN;
DR   Q6AW46, EST5A_MOUSE;  Q5GRG2, EST5A_RAT  ;  Q3T930, EST5A_SHEEP;
DR   O16170, EST5B_DROMI;  O16172, EST5B_DROPE;  P25726, EST5B_DROPS;
DR   O16169, EST5C_DROMI;  O16171, EST5C_DROPE;  P25725, EST5C_DROPS;
DR   P10095, EST5_DROMO ;  Q63010, EST5_RAT   ;  B2D0J5, EST6_APIME ;
DR   P47982, EST6_DROMA ;  P08171, EST6_DROME ;  Q08662, EST6_DROSI ;
DR   O33407, ESTA_PSEAE ;  Q6B6R8, ESTA_PSEPU ;  P81012, ESTA_SCHGA ;
DR   P81011, ESTB_SCHGA ;  P35501, ESTE_MYZPE ;  P35502, ESTF_MYZPE ;
DR   P23953, ESTN_MOUSE ;  P18167, ESTP_DROME ;  Q88QS0, ESTP_PSEPK ;
DR   Q05487, ESTS_DROVI ;  O32232, EST_BACSU  ;  Q06174, EST_GEOSE  ;
DR   Q9HZY8, EST_PSEAE  ;  P96688, NAP_BACSU  ;  P81098, SFAH_HELAN ;
DR   O31452, YBFK_BACSU ;
//
ID   3.1.1.2
DE   Arylesterase.
AN   A-esterase.
AN   Paraoxonase.
CA   A phenyl acetate + H(2)O = a phenol + acetate.
CC   -!- Acts on many phenolic esters.
CC   -!- It is likely that the three forms of human paraoxonase are lactonases
CC       rather than aromatic esterases.
CC   -!- The natural substrates of the paraoxonases are lactones, with (+-)-5-
CC       hydroxy-6E,8Z,11Z,4Z-eicostetraenoic-acid 1,5-lactone being the best
CC       substrate.
DR   P22862, ESTE_PSEFL ;  Q07792, ESTE_VIBMI ;  P27169, PON1_HUMAN ;
DR   P52430, PON1_MOUSE ;  P27170, PON1_RABIT ;  P55159, PON1_RAT   ;
DR   Q58DS7, PON2_BOVIN ;  P54832, PON2_CANFA ;  Q90952, PON2_CHICK ;
DR   Q15165, PON2_HUMAN ;  Q91090, PON2_MELGA ;  Q62086, PON2_MOUSE ;
DR   Q6AXM8, PON2_RAT   ;  Q15166, PON3_HUMAN ;  Q62087, PON3_MOUSE ;
DR   Q9BGN0, PON3_RABIT ;  Q68FP2, PON3_RAT   ;
//
ID   3.1.1.3
DE   Triacylglycerol lipase.
AN   Lipase.
AN   Tributyrase.
AN   Triglyceride lipase.
CA   Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
CC   -!- The pancreatic enzyme acts only on an ester-water interface; the
CC       outer ester links are preferentially hydrolyzed.
PR   PROSITE; PDOC00110;
PR   PROSITE; PDOC00112;
DR   Q0P5B7, AAAD_BOVIN ;  P22760, AAAD_HUMAN ;  Q99PG0, AAAD_MOUSE ;
DR   Q7M370, AAAD_RABIT ;  Q9QZH8, AAAD_RAT   ;  Q0V1P1, AT151_PHANO;
DR   A6REI4, ATG15_AJECN;  Q75EN3, ATG15_ASHGO;  A1C6D6, ATG15_ASPCL;
DR   Q4X180, ATG15_ASPFU;  A2QGD9, ATG15_ASPNC;  Q0CXU6, ATG15_ASPTN;
DR   Q5A4N0, ATG15_CANAL;  Q6FPI6, ATG15_CANGA;  Q2H6M8, ATG15_CHAGB;
DR   O13444, ATG15_CLAFU;  Q1DZE0, ATG15_COCIM;  P0CO61, ATG15_CRYNB;
DR   P0CO60, ATG15_CRYNJ;  Q6BLM0, ATG15_DEBHA;  Q5B0L1, ATG15_EMENI;
DR   Q6CU02, ATG15_KLULA;  A5E567, ATG15_LODEL;  A1DH10, ATG15_NEOFI;
DR   Q7RYY1, ATG15_NEUCR;  A7KAM5, ATG15_PENCW;  A7KAJ9, ATG15_PICAN;
DR   A5DC90, ATG15_PICGU;  A3LV34, ATG15_PICST;  O13934, ATG15_SCHPO;
DR   Q4PHZ2, ATG15_USTMA;  A7TG13, ATG15_VANPO;  Q6C2N7, ATG15_YARLI;
DR   A6ZTP2, ATG15_YEAS7;  P25641, ATG15_YEAST;  P30122, CEL_BOVIN  ;
DR   P19835, CEL_HUMAN  ;  Q64285, CEL_MOUSE  ;  P07882, CEL_RAT    ;
DR   P37957, ESTA_BACSU ;  Q79F14, ESTB_BACSU ;  P38139, LDH1_YEAST ;
DR   Q9P4E5, LIP10_CANAL;  Q71DJ5, LIP1_ARATH ;  O94091, LIP1_CANAL ;
DR   P20261, LIP1_CANRU ;  P17573, LIP1_GEOCN ;  P79066, LIP1_GEOFE ;
DR   P19833, LIP1_MORS1 ;  P40601, LIP1_PHOLU ;  Q02104, LIP1_PSYIM ;
DR   Q5HCM7, LIP1_STAAC ;  P65288, LIP1_STAAM ;  P65289, LIP1_STAAN ;
DR   Q6GDD3, LIP1_STAAR ;  Q6G604, LIP1_STAAS ;  Q8NUI5, LIP1_STAAW ;
DR   Q9S2A5, LIP1_STRCO ;  Q99156, LIP1_YARLI ;  Q67ZU1, LIP2_ARATH ;
DR   Q9P8W5, LIP2_CANAL ;  P32946, LIP2_CANRU ;  P22394, LIP2_GEOCN ;
DR   P24484, LIP2_MORS1 ;  Q5HJ48, LIP2_STAAC ;  Q99WQ6, LIP2_STAAM ;
DR   Q7A7P2, LIP2_STAAN ;  Q6GJZ6, LIP2_STAAR ;  Q6GCF1, LIP2_STAAS ;
DR   P10335, LIP2_STAAU ;  Q8NYC2, LIP2_STAAW ;  Q93J06, LIP2_STRCO ;
DR   Q9P8W2, LIP3_CANAL ;  P32947, LIP3_CANRU ;  P24640, LIP3_MORS1 ;
DR   Q96VC9, LIP3_YARLI ;  Q9P8W1, LIP4_CANAL ;  P32948, LIP4_CANRU ;
DR   Q9P8W0, LIP5_CANAL ;  P32949, LIP5_CANRU ;  Q9P4E8, LIP6_CANAL ;
DR   Q9P4E7, LIP7_CANAL ;  Q9P8V9, LIP8_CANAL ;  Q9P4E6, LIP9_CANAL ;
DR   P26504, LIPA_PSEFL ;  P41365, LIPB_CANAR ;  P41773, LIPB_PSEFL ;
DR   Q3SZ79, LIPC_BOVIN ;  P11150, LIPC_HUMAN ;  P27656, LIPC_MOUSE ;
DR   O46559, LIPC_RABIT ;  P07867, LIPC_RAT   ;  P40600, LIPE_AERHY ;
DR   Q9Y5X9, LIPE_HUMAN ;  Q9WVG5, LIPE_MOUSE ;  Q8VBX1, LIPE_RAT   ;
DR   Q29458, LIPG_BOVIN ;  P80035, LIPG_CANFA ;  P07098, LIPG_HUMAN ;
DR   Q9CPP7, LIPG_MOUSE ;  P04634, LIPG_RAT   ;  P50903, LIPP_CAVPO ;
DR   P83629, LIPP_FELCA ;  P29183, LIPP_HORSE ;  P16233, LIPP_HUMAN ;
DR   Q6P8U6, LIPP_MOUSE ;  Q64425, LIPP_MYOCO ;  P00591, LIPP_PIG   ;
DR   Q02157, LIPP_RABIT ;  P27657, LIPP_RAT   ;  O88354, LIPP_SPETR ;
DR   A5PK46, LIPR2_BOVIN;  P81139, LIPR2_CAVPO;  P54317, LIPR2_HUMAN;
DR   P17892, LIPR2_MOUSE;  Q64424, LIPR2_MYOCO;  P54318, LIPR2_RAT  ;
DR   Q17RR3, LIPR3_HUMAN;  P29605, LIPT_BURCE ;  P22088, LIP_BURCE  ;
DR   Q05489, LIP_BURGL  ;  P26876, LIP_PSEAE  ;  P08658, LIP_PSEFR  ;
DR   P25275, LIP_PSES5  ;  P26877, LIP_PSEU0  ;  Q7M4U7, LIP_RHIJA  ;
DR   P19515, LIP_RHIMI  ;  P61871, LIP_RHINI  ;  P61872, LIP_RHIOR  ;
DR   P0C0R3, LIP_STAEP  ;  Q5HKP6, LIP_STAEQ  ;  P0C0R4, LIP_STAES  ;
DR   P04635, LIP_STAHY  ;  Q93MW7, LIP_STRRM  ;  O59952, LIP_THELA  ;
DR   P15493, LIP_VIBCH  ;  Q2KI18, PLPL2_BOVIN;  Q96AD5, PLPL2_HUMAN;
DR   Q8BJ56, PLPL2_MOUSE;  P0C548, PLPL2_RAT  ;  Q9NST1, PLPL3_HUMAN;
DR   Q91WW7, PLPL3_MOUSE;  P41247, PLPL4_HUMAN;  Q9LZA6, SDP1_ARATH ;
DR   P54857, TGL2_YEAST ;  P40308, TGL3_YEAST ;  P36165, TGL4_YEAST ;
DR   Q12043, TGL5_YEAST ;
//
ID   3.1.1.4
DE   Phospholipase A(2).
AN   Lecithinase A.
AN   Phosphatidase.
AN   Phosphatidolipase.
AN   Phosphatidylcholine 2-acylhydrolase.
AN   Phospholipase A2.
CA   Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine +
CA   a carboxylate.
CF   Calcium.
CC   -!- Also acts on phosphatidylethanolamine, choline plasmalogen and
CC       phosphatides, removing the fatty acid attached to the 2-position.
PR   PROSITE; PDOC00109;
DR   Q9TWL9, COMA_CONMA ;  P59888, IPTXI_PANIM;  Q06478, PA11_DOLMA ;
DR   P53357, PA12_DOLMA ;  P0A922, PA1_ECO57  ;  P0A921, PA1_ECOLI  ;
DR   P37446, PA1_KLEPN  ;  Q9K0U7, PA1_NEIMB  ;  P37447, PA1_PROVU  ;
DR   P0A232, PA1_SALTI  ;  P0A231, PA1_SALTY  ;  P0A923, PA1_SHIFL  ;
DR   Q3ZU95, PA1_VESGE  ;  P51528, PA1_VESMC  ;  P49369, PA1_VESVU  ;
DR   P00606, PA20_BUNMU ;  Q8UW08, PA20_LAPHA ;  P08873, PA20_NOTSC ;
DR   P20254, PA20_PSEAU ;  Q9PUH4, PA210_AUSSU;  Q9PUH3, PA211_AUSSU;
DR   Q9PUH2, PA212_AUSSU;  P0CAS3, PA212_CRODR;  Q9PUH1, PA213_AUSSU;
DR   P0CAS4, PA213_CRODR;  Q9PUH0, PA214_AUSSU;  Q9PUG9, PA215_AUSSU;
DR   P0CAS5, PA215_CRODU;  Q9PUG8, PA216_AUSSU;  P0CAS6, PA216_CRODU;
DR   Q9PUG7, PA217_AUSSU;  P0CAS7, PA217_CRODU;  P84475, PA21A_BUNCA;
DR   P81236, PA21B_ACAAN;  P59359, PA21B_AUSSU;  P81243, PA21B_BOTJA;
DR   P00593, PA21B_BOVIN;  Q8QFW4, PA21B_BUNCE;  Q90WA7, PA21B_BUNFA;
DR   P00617, PA21B_BUNMU;  P06596, PA21B_CANFA;  P43434, PA21B_CAVPO;
DR   P24293, PA21B_ERIMA;  P04417, PA21B_GLOBL;  P14418, PA21B_GLOHA;
DR   P00594, PA21B_HORSE;  P04054, PA21B_HUMAN;  P19000, PA21B_LATLA;
DR   P00611, PA21B_LATSE;  P24644, PA21B_MATBI;  P21790, PA21B_MICNI;
DR   P25072, PA21B_MICTM;  Q9Z0Y2, PA21B_MOUSE;  P00599, PA21B_NAJME;
DR   P00602, PA21B_NAJMO;  P25498, PA21B_NAJOX;  P60043, PA21B_NAJSG;
DR   P80966, PA21B_OPHHA;  P00625, PA21B_OVOOK;  P00614, PA21B_OXYSC;
DR   P00592, PA21B_PIG  ;  P06859, PA21B_PROFL;  Q91506, PA21B_PROMU;
DR   P04056, PA21B_PSEAU;  Q9W7J4, PA21B_PSETE;  Q7M334, PA21B_RABIT;
DR   P04055, PA21B_RAT  ;  P14419, PA21B_SHEEP;  P86043, PA21B_STRCA;
DR   P20476, PA21B_TRIGA;  P14420, PA21B_VIPAE;  Q8JFG0, PA21B_VIPAP;
DR   Q1RP79, PA21P_VIPNI;  Q3C2C2, PA21_ACAPL ;  P51972, PA21_AGKPI ;
DR   P20474, PA21_BOTAS ;  Q8QG87, PA21_BOTIN ;  P0C8M1, PA21_BOTMO ;
DR   Q75S48, PA21_BUNCA ;  Q7T2Q5, PA21_BUNFL ;  P0CAR9, PA21_CERCE ;
DR   P86529, PA21_DABRR ;  Q90ZZ9, PA21_ECHCO ;  P00595, PA21_HEMHA ;
DR   P0C932, PA21_LACMU ;  P00598, PA21_NAJAT ;  P00596, PA21_NAJKA ;
DR   P86119, PA21_OPICY ;  Q45Z30, PA21_TROCA ;  P84472, PA22A_BUNCA;
DR   Q1RP78, PA22P_VIPNI;  P81237, PA22_ACAAN ;  Q3C2C1, PA22_ACAPL ;
DR   P07037, PA22_ASPSC ;  Q9PUI1, PA22_AUSSU ;  P00621, PA22_BITNA ;
DR   P86389, PA22_BOTAS ;  P84397, PA22_BOTIN ;  Q8QFW3, PA22_BUNCE ;
DR   Q90WA8, PA22_BUNFA ;  Q7T2Q4, PA22_BUNFL ;  P00618, PA22_BUNMU ;
DR   P0CAS0, PA22_CERCE ;  P24294, PA22_ERIMA ;  P20249, PA22_GLOBL ;
DR   P18997, PA22_GLOHA ;  P80003, PA22_HELSU ;  P0C933, PA22_LACMU ;
DR   P10116, PA22_LATCO ;  Q8UUI4, PA22_LATLA ;  P24645, PA22_MATBI ;
DR   P21791, PA22_MICNI ;  Q91133, PA22_NAJAT ;  P00597, PA22_NAJKA ;
DR   P00600, PA22_NAJME ;  P00603, PA22_NAJMO ;  P60044, PA22_NAJSG ;
DR   P00608, PA22_NOTSC ;  Q9DF33, PA22_OPHHA ;  P86120, PA22_OPICY ;
DR   P04416, PA22_PIG   ;  Q9I968, PA22_PROMU ;  Q9W7J3, PA22_PSETE ;
DR   P81478, PA22_TRIGA ;  Q45Z29, PA22_TROCA ;  Q10755, PA22_VIPAZ ;
DR   Q9PRG0, PA23_AUSSU ;  P58464, PA23_BOTPI ;  P00619, PA23_BUNMU ;
DR   P0CV89, PA23_CROAT ;  P86368, PA23_DABRR ;  Q910A0, PA23_ECHCO ;
DR   P14421, PA23_GLOHA ;  P16354, PA23_HELSU ;  Q8UUI0, PA23_LATCO ;
DR   Q8UUI3, PA23_LATLA ;  P00612, PA23_LATSE ;  P21792, PA23_MICNI ;
DR   P00601, PA23_NAJME ;  P00604, PA23_NAJMO ;  P86542, PA23_NAJNA ;
DR   P00605, PA23_NAJNG ;  P60045, PA23_NAJSG ;  P00609, PA23_NOTSC ;
DR   Q9DF56, PA23_OPHHA ;  P00616, PA23_OXYSC ;  P20251, PA23_PSEAU ;
DR   P81480, PA23_TRIGA ;  Q45Z28, PA23_TROCA ;  P82894, PA23_VIRST ;
DR   A4IFJ5, PA24A_BOVIN;  P49147, PA24A_CHICK;  P50392, PA24A_DANRE;
DR   O77793, PA24A_HORSE;  P47712, PA24A_HUMAN;  P47713, PA24A_MOUSE;
DR   Q5R8A5, PA24A_PONAB;  Q9TT38, PA24A_RABIT;  P50393, PA24A_RAT  ;
DR   Q7T0T9, PA24A_XENLA;  B1WAZ6, PA24A_XENTR;  P0C869, PA24B_HUMAN;
DR   P0C871, PA24B_MOUSE;  Q9UP65, PA24C_HUMAN;  Q86XP0, PA24D_HUMAN;
DR   Q50L43, PA24D_MOUSE;  Q3MJ16, PA24E_HUMAN;  Q50L42, PA24E_MOUSE;
DR   Q68DD2, PA24F_HUMAN;  Q50L41, PA24F_MOUSE;  Q9PUI0, PA24_AUSSU ;
DR   P0CAR8, PA24_BOTJR ;  P17934, PA24_BUNMU ;  Q02471, PA24_DABRU ;
DR   P59170, PA24_ECHCS ;  O42187, PA24_GLOHA ;  Q8UUH9, PA24_LATCO ;
DR   Q8UUI2, PA24_LATLA ;  P00613, PA24_LATSE ;  Q6T179, PA24_NAJSG ;
DR   P81479, PA24_TRIGA ;  Q45Z27, PA24_TROCA ;  P82895, PA24_VIRST ;
DR   Q9PUH9, PA25_AUSSU ;  P59018, PA25_BUNMU ;  P84674, PA25_DABRR ;
DR   P59171, PA25_ECHOC ;  P59172, PA25_ECHPL ;  O42189, PA25_GLOHA ;
DR   Q8UW31, PA25_LAPHA ;  Q8UUH8, PA25_LATCO ;  Q8UUI1, PA25_LATLA ;
DR   Q5G291, PA25_NAJSG ;  P20252, PA25_PSEAU ;  P70090, PA25_TRIGA ;
DR   Q45Z26, PA25_TROCA ;  P82896, PA25_VIRST ;  P0CAS2, PA26A_CRODO;
DR   Q9PUH8, PA26_AUSSU ;  P00627, PA26_BUNFA ;  Q90251, PA26_BUNMU ;
DR   P0CAS1, PA26_CRODM ;  O42190, PA26_GLOHA ;  Q8UUH7, PA26_LATCO ;
DR   Q5G290, PA26_NAJSG ;  P70088, PA26_TRIGA ;  Q45Z25, PA26_TROCA ;
DR   Q9PUH7, PA27_AUSSU ;  Q9PU97, PA27_BUNMU ;  P31100, PA27_DABRU ;
DR   O42191, PA27_GLOHA ;  Q8UW30, PA27_LAPHA ;  P70089, PA27_TRIGA ;
DR   Q9PWR6, PA27_VIPPA ;  Q9PUH6, PA28_AUSSU ;  P59071, PA28_DABRR ;
DR   O42192, PA28_GLOHA ;  Q9PUH5, PA29_AUSSU ;  P20253, PA29_PSEAU ;
DR   P85062, PA2A1_ACASE;  Q8AY48, PA2A1_BUNCA;  Q7T1R0, PA2A1_BUNFL;
DR   P85060, PA2A2_ACASS;  Q7T1R1, PA2A2_BUNFL;  P85061, PA2A3_ACASS;
DR   Q6YNQ0, PA2A3_BUNCA;  Q75S51, PA2A4_BUNCA;  P86523, PA2AA_ACAAN;
DR   Q7SID6, PA2A_AGKAC ;  Q9PVF1, PA2A_AGKRH ;  Q6YIJ3, PA2A_BUNCA ;
DR   P00628, PA2A_BUNFA ;  Q9PTA1, PA2A_BUNMU ;  P86169, PA2A_CRODR ;
DR   Q7LZQ4, PA2A_GLOUS ;  Q9I847, PA2A_LATSE ;  P81166, PA2A_MICNI ;
DR   Q92084, PA2A_NAJSP ;  P59264, PA2A_PROFL ;  Q90W39, PA2A_PROMU ;
DR   P20255, PA2A_PSEAU ;  P20258, PA2A_PSEPO ;  P23026, PA2A_PSETE ;
DR   P00626, PA2A_VIPAA ;  Q98996, PA2A_VIPPA ;  P86803, PA2B1_BOTMA;
DR   P0CAS9, PA2B1_MICPY;  P82892, PA2B1_VIRST;  P45881, PA2B2_BOTJR;
DR   P86804, PA2B2_BOTMA;  P82893, PA2B2_VIRST;  P86805, PA2B9_CRODM;
DR   P86806, PA2BX_CRODM;  Q1ZY03, PA2B_AGKAC ;  Q9PVF0, PA2B_AGKRH ;
DR   Q802I1, PA2B_BUNCA ;  P00629, PA2B_BUNFA ;  Q9PTA7, PA2B_BUNMU ;
DR   P62022, PA2B_CRODU ;  P62023, PA2B_CROSS ;  Q9I846, PA2B_LATSE ;
DR   P81167, PA2B_MICNI ;  Q92085, PA2B_NAJSP ;  P59265, PA2B_PROFL ;
DR   P22640, PA2B_PROMU ;  P20259, PA2B_PSEPO ;  P23027, PA2B_PSETE ;
DR   P14424, PA2B_VIPAA ;  P31859, PA2B_VIPDI ;  Q9PVE9, PA2C_AGKRH ;
DR   Q9PTA6, PA2C_BUNMU ;  P24027, PA2C_CRODU ;  Q9I845, PA2C_LATSE ;
DR   Q92086, PA2C_NAJSP ;  P20256, PA2C_PSEAU ;  P20260, PA2C_PSEPO ;
DR   P30811, PA2C_PSETE ;  P11407, PA2C_VIPAA ;  P0CAT0, PA2D5_MICPY;
DR   P0CAT1, PA2D6_MICPY;  Q9PVF4, PA2D_AGKRH ;  Q7LZQ6, PA2D_BUNFA ;
DR   Q9PTA5, PA2D_BUNMU ;  Q9I844, PA2D_LATSE ;  Q9I900, PA2D_NAJSP ;
DR   P04057, PA2D_PSEAU ;  P23028, PA2D_PSETE ;  Q9PVF2, PA2E_AGKRH ;
DR   Q9I843, PA2E_LATSE ;  Q9PSN5, PA2E_NOTSC ;  P20257, PA2E_PSEAU ;
DR   Q9I842, PA2F_LATSE ;  Q1JPB9, PA2G3_BOVIN;  Q9NZ20, PA2G3_HUMAN;
DR   P39877, PA2G5_HUMAN;  P97391, PA2G5_MOUSE;  P51433, PA2G5_RAT  ;
DR   O60733, PA2G6_HUMAN;  P97819, PA2G6_MOUSE;  P97570, PA2G6_RAT  ;
DR   Q56JZ2, PA2GA_BOVIN;  P47711, PA2GA_CAVPO;  P14555, PA2GA_HUMAN;
DR   P31482, PA2GA_MOUSE;  P14422, PA2GA_RABIT;  P14423, PA2GA_RAT  ;
DR   P48076, PA2GC_MOUSE;  P39878, PA2GC_RAT  ;  Q9UNK4, PA2GD_HUMAN;
DR   Q9WVF6, PA2GD_MOUSE;  Q9NZK7, PA2GE_HUMAN;  Q9QUL3, PA2GE_MOUSE;
DR   Q9BZM2, PA2GF_HUMAN;  Q9QZT4, PA2GF_MOUSE;  O15496, PA2GX_HUMAN;
DR   Q9QXX3, PA2GX_MOUSE;  Q9QZT3, PA2GX_RAT  ;  P0C551, PA2G_BUNFA ;
DR   Q9I837, PA2G_LATSE ;  P20250, PA2G_PSEAU ;  Q8JFG2, PA2H_LATSE ;
DR   Q8JFB2, PA2I_LATSE ;  P20381, PA2J_PROFL ;  Q9DF52, PA2K_BUNCE ;
DR   P14615, PA2N_BUNFA ;  P48650, PA2N_ECHCA ;  A4FS04, PA2N_NAJAT ;
DR   Q805A2, PA2N_PROFL ;  P34180, PA2N_VIPAA ;  Q92147, PA2P_PROFL ;
DR   Q8JIG0, PA2Q_PROFL ;  P86456, PA2R4_BOTAL;  P59067, PA2S_AUSSU ;
DR   P0C942, PA2T1_LACMU;  P84474, PA2T2_BUNCA;  P0C943, PA2T2_LACMU;
DR   P59068, PA2T_AUSSU ;  Q7LZG2, PA2T_OXYSC ;  P59069, PA2U_AUSSU ;
DR   P59070, PA2V_AUSSU ;  Q02517, PA2W_PROFL ;  P14411, PA2X_BUNFA ;
DR   P20146, PA2X_NOTSC ;  P06860, PA2X_PROFL ;  Q90Y77, PA2Y_PROFL ;
DR   Q8WS88, PA2_ADAPA  ;  Q9PSF9, PA2_AGKBI  ;  P08872, PA2_AIPLA  ;
DR   Q9BMK4, PA2_APICC  ;  Q7M4I5, PA2_APIDO  ;  P00630, PA2_APIME  ;
DR   P59066, PA2_AUSSU  ;  P00622, PA2_BITCA  ;  P00620, PA2_BITGA  ;
DR   P82971, PA2_BOMTE  ;  Q9PRZ0, PA2_BOTJA  ;  Q9I8F8, PA2_BOTPC  ;
DR   P86780, PA2_BUNCI  ;  P86517, PA2_CARAE  ;  P21789, PA2_CERCE  ;
DR   P00623, PA2_CROAD  ;  P00624, PA2_CROAT  ;  P81458, PA2_DABRR  ;
DR   P18999, PA2_DABRU  ;  P00610, PA2_ENHSC  ;  P0C8L9, PA2_HADGE  ;
DR   P04362, PA2_HELHO  ;  P84651, PA2_LACST  ;  Q7M4I6, PA2_MEGPE  ;
DR   P15445, PA2_NAJNA  ;  P14556, PA2_NAJPA  ;  Q10756, PA2_NAJSP  ;
DR   Q7LZG5, PA2_NOTSC  ;  Q8JIY9, PA2_PROJR  ;  Q7LZG3, PA2_PSEPP  ;
DR   P43318, PA2_RHONO  ;  C1JAR9, PA2_SCOVI  ;  P84736, PA2_TRIBL  ;
DR   Q910A1, PA2_VIPAA  ;  P31854, PA2_VIPBB  ;  Q7M3V3, PAO2_VESOR ;
DR   Q9BZM1, PG12A_HUMAN;  Q9EPR2, PG12A_MOUSE;  Q6PXP0, PHLIP_ANUPH;
DR   Q9XG80, PLA21_ORYSJ;  Q9XG81, PLA22_ORYSJ;  Q10E50, PLA23_ORYSJ;
DR   O70320, PLB1_CAVPO ;  Q6P1J6, PLB1_HUMAN ;  Q06HQ7, PLB1_MONDO ;
DR   Q3TTY0, PLB1_MOUSE ;  Q05017, PLB1_RABIT ;  O54728, PLB1_RAT   ;
//
ID   3.1.1.5
DE   Lysophospholipase.
AN   Lecithinase B.
AN   Lysolecithinase.
AN   Phospholipase B.
CA   2-lysophosphatidylcholine + H(2)O = glycerophosphocholine +
CA   a carboxylate.
PR   PROSITE; PDOC00279;
DR   Q86U10, LPP60_HUMAN;  A0JNU3, LPP60_MOUSE;  O88202, LPP60_RAT  ;
DR   Q05315, LPPL_HUMAN ;  P97400, LPPL_MOUSE ;  P79238, LPPL_PONPY ;
DR   Q756Z0, NTE1_ASHGO ;  A1C9L6, NTE1_ASPCL ;  Q4WA15, NTE1_ASPFU ;
DR   A2R350, NTE1_ASPNC ;  Q2UDH2, NTE1_ASPOR ;  Q0CNC7, NTE1_ASPTN ;
DR   Q5A368, NTE1_CANAL ;  Q6FKJ1, NTE1_CANGA ;  Q2H0D3, NTE1_CHAGB ;
DR   Q1DLC7, NTE1_COCIM ;  P0CP37, NTE1_CRYNB ;  P0CP36, NTE1_CRYNJ ;
DR   Q6BQK9, NTE1_DEBHA ;  Q5BAE9, NTE1_EMENI ;  Q8SVN8, NTE1_ENCCU ;
DR   Q6CWC2, NTE1_KLULA ;  A5E708, NTE1_LODEL ;  A4QVZ8, NTE1_MAGO7 ;
DR   A1D9Y2, NTE1_NEOFI ;  Q7S8J1, NTE1_NEUCR ;  Q0UJ42, NTE1_PHANO ;
DR   A5DHA3, NTE1_PICGU ;  A3LYZ4, NTE1_PICST ;  Q9USJ4, NTE1_SCHPO ;
DR   Q4PF83, NTE1_USTMA ;  Q6CF18, NTE1_YARLI ;  Q04958, NTE1_YEAST ;
DR   A4IFJ5, PA24A_BOVIN;  P49147, PA24A_CHICK;  P50392, PA24A_DANRE;
DR   O77793, PA24A_HORSE;  P47712, PA24A_HUMAN;  P47713, PA24A_MOUSE;
DR   Q5R8A5, PA24A_PONAB;  Q9TT38, PA24A_RABIT;  P50393, PA24A_RAT  ;
DR   Q7T0T9, PA24A_XENLA;  B1WAZ6, PA24A_XENTR;  Q7M3V4, PAO1_VESOR ;
DR   B0Y665, PLB1_ASPFC ;  P0C957, PLB1_ASPFU ;  Q9UWF6, PLB1_CANAL ;
DR   Q8TG07, PLB1_CANGA ;  O70320, PLB1_CAVPO ;  P0CP75, PLB1_CRYNB ;
DR   P0CP74, PLB1_CRYNJ ;  Q9P8P2, PLB1_CRYNV ;  Q6P1J6, PLB1_HUMAN ;
DR   Q06HQ7, PLB1_MONDO ;  Q3TTY0, PLB1_MOUSE ;  P39457, PLB1_PENCH ;
DR   Q05017, PLB1_RABIT ;  O54728, PLB1_RAT   ;  P78854, PLB1_SCHPO ;
DR   Q11121, PLB1_TORDE ;  P39105, PLB1_YEAST ;  B0Y1M7, PLB2_ASPFC ;
DR   Q9P8P4, PLB2_ASPFU ;  O93795, PLB2_CANAL ;  Q8TG06, PLB2_CANGA ;
DR   O13857, PLB2_SCHPO ;  Q03674, PLB2_YEAST ;  B0XZV8, PLB3_ASPFC ;
DR   P0C958, PLB3_ASPFU ;  Q9UVX1, PLB3_CANAL ;  Q08108, PLB3_YEAST ;
DR   Q9P327, PLB4_SCHPO ;  Q9Y7N6, PLB5_SCHPO ;  Q9UTH5, PLB6_SCHPO ;
DR   O59863, PLB_KLULA  ;  O42790, PLB_NEUCR  ;  P59588, PLDB_ECOL6 ;
DR   P07000, PLDB_ECOLI ;  P44800, PLDB_HAEIN ;  Q8IY17, PLPL6_HUMAN;
DR   Q3TRM4, PLPL6_MOUSE;  Q5RDS0, PLPL6_PONAB;  Q9NP80, PLPL8_HUMAN;
DR   Q8K1N1, PLPL8_MOUSE;  Q5XTS1, PLPL8_RABIT;  Q9UHV8, PP13_HUMAN ;
DR   B3MRI9, SWS_DROAN  ;  B3NY03, SWS_DROER  ;  B4JLX2, SWS_DROGR  ;
DR   Q9U969, SWS_DROME  ;  B4L535, SWS_DROMO  ;  B4H3U8, SWS_DROPE  ;
DR   B5DKS8, SWS_DROPS  ;  B4IL64, SWS_DROSE  ;  B4M709, SWS_DROVI  ;
DR   B4N1W9, SWS_DROWI  ;  B4Q0P3, SWS_DROYA  ;  P0ADA2, TESA_ECOL6 ;
DR   P0ADA1, TESA_ECOLI ;
//
ID   3.1.1.6
DE   Acetylesterase.
AN   C-esterase (in animal tissues).
CA   An acetic ester + H(2)O = an alcohol + acetate.
//
ID   3.1.1.7
DE   Acetylcholinesterase.
AN   Choline esterase I.
AN   Cholinesterase.
AN   True cholinesterase.
CA   Acetylcholine + H(2)O = choline + acetate.
CC   -!- Acts on a variety of acetic esters.
CC   -!- Also catalyzes transacetylations.
PR   PROSITE; PDOC00112;
DR   Q27459, ACE1_CAEBR ;  P38433, ACE1_CAEEL ;  Q9NDG8, ACE4_CAEBR ;
DR   Q869C3, ACES_ANOGA ;  P56161, ACES_ANOST ;  P23795, ACES_BOVIN ;
DR   Q92035, ACES_BUNFA ;  P36196, ACES_CHICK ;  Q86GC8, ACES_CULPI ;
DR   Q867X3, ACES_CULPP ;  Q867X2, ACES_CULQU ;  Q86GC9, ACES_CULTO ;
DR   Q9DDE3, ACES_DANRE ;  P07140, ACES_DROME ;  O42275, ACES_ELEEL ;
DR   O62763, ACES_FELCA ;  P22303, ACES_HUMAN ;  Q27677, ACES_LEPDE ;
DR   P21836, ACES_MOUSE ;  Q92081, ACES_MYXGL ;  Q7LZG1, ACES_NAJOX ;
DR   Q29499, ACES_RABIT ;  P37136, ACES_RAT   ;  P04058, ACES_TORCA ;
DR   P07692, ACES_TORMA ;
//
ID   3.1.1.8
DE   Cholinesterase.
AN   Acylcholine acylhydrolase.
AN   Benzoylcholinesterase.
AN   Butyrylcholine esterase.
AN   Choline esterase II (unspecific).
AN   Non-specific cholinesterase.
AN   Pseudocholinesterase.
CA   An acylcholine + H(2)O = choline + a carboxylate.
CC   -!- Acts on a variety of choline esters and a few other compounds.
PR   PROSITE; PDOC00112;
DR   Q95000, CHLE1_BRALA;  Q95001, CHLE2_BRALA;  P32749, CHLE_BOVIN ;
DR   P32750, CHLE_CANFA ;  O62760, CHLE_FELCA ;  P81908, CHLE_HORSE ;
DR   P06276, CHLE_HUMAN ;  P32751, CHLE_MACMU ;  Q5UR02, CHLE_MIMIV ;
DR   Q03311, CHLE_MOUSE ;  O62761, CHLE_PANTT ;  P32752, CHLE_PIG   ;
DR   P21927, CHLE_RABIT ;  P32753, CHLE_SHEEP ;
//
ID   3.1.1.9
DE   Deleted entry.
//
ID   3.1.1.10
DE   Tropinesterase.
AN   Atropine acylhydrolase.
AN   Atropinesterase.
CA   Atropine + H(2)O = tropine + tropate.
CC   -!- Also acts on cocaine and other tropine esters.
DR   P07383, TPES_PSEPU ;
//
ID   3.1.1.11
DE   Pectinesterase.
AN   Pectin demethoxylase.
AN   Pectin methoxylase.
AN   Pectin methylesterase.
CA   Pectin + n H(2)O = n methanol + pectate.
PR   PROSITE; PDOC00413;
DR   O64479, PME10_ARATH;  Q9SIJ9, PME11_ARATH;  O48711, PME12_ARATH;
DR   Q7Y201, PME13_ARATH;  Q9ZQA4, PME14_ARATH;  Q9ZQA3, PME15_ARATH;
DR   Q9SKX2, PME16_ARATH;  O22149, PME17_ARATH;  Q1JPL7, PME18_ARATH;
DR   Q84JX1, PME19_ARATH;  Q43867, PME1_ARATH ;  O04886, PME1_CITSI ;
DR   P83947, PME1_FICAW ;  P58601, PME1_RALSO ;  P14280, PME1_SOLLC ;
DR   O22256, PME20_ARATH;  Q8GX86, PME21_ARATH;  P09607, PME21_SOLLC;
DR   Q9M9W7, PME22_ARATH;  Q96575, PME22_SOLLC;  Q8GXA1, PME23_ARATH;
DR   Q9SG77, PME24_ARATH;  Q94CB1, PME25_ARATH;  Q9LUL8, PME26_ARATH;
DR   Q3E8Z8, PME28_ARATH;  Q4PSN0, PME29_ARATH;  Q42534, PME2_ARATH ;
DR   O04887, PME2_CITSI ;  P24791, PME2_RALSO ;  Q3EAY9, PME30_ARATH;
DR   Q9LVQ0, PME31_ARATH;  Q9LXK7, PME32_ARATH;  Q9STY3, PME33_ARATH;
DR   Q9M3B0, PME34_ARATH;  Q9LYT5, PME35_ARATH;  Q84R10, PME36_ARATH;
DR   Q5MFV6, PME37_ARATH;  O81320, PME38_ARATH;  O81415, PME39_ARATH;
DR   O49006, PME3_ARATH ;  P83948, PME3_CITSI ;  Q43111, PME3_PHAVU ;
DR   Q96576, PME3_SOLLC ;  O81301, PME40_ARATH;  Q8RXK7, PME41_ARATH;
DR   Q1PEC0, PME42_ARATH;  O23447, PME43_ARATH;  Q9SMY7, PME44_ARATH;
DR   Q9SMY6, PME45_ARATH;  Q9FF78, PME46_ARATH;  Q9FF77, PME47_ARATH;
DR   Q9LY19, PME48_ARATH;  Q9LY18, PME49_ARATH;  O80722, PME4_ARATH ;
DR   Q9LY17, PME50_ARATH;  Q9LXD9, PME51_ARATH;  O04953, PME52_ARATH;
DR   Q8VYZ3, PME53_ARATH;  Q3E989, PME54_ARATH;  Q3E9D3, PME55_ARATH;
DR   Q4PT34, PME56_ARATH;  Q9MAL0, PME57_ARATH;  Q9FJ21, PME58_ARATH;
DR   Q9FHN5, PME59_ARATH;  Q5MFV8, PME5_ARATH ;  Q9FHN4, PME60_ARATH;
DR   Q9FK05, PME61_ARATH;  Q9FM79, PME62_ARATH;  Q9FKF3, PME63_ARATH;
DR   Q8L7Q7, PME64_ARATH;  Q4PSQ5, PME66_ARATH;  Q9LSP1, PME67_ARATH;
DR   Q8LPF3, PME68_ARATH;  O49298, PME6_ARATH ;  Q9SRX4, PME7_ARATH ;
DR   O23038, PME8_ARATH ;  B0Y9F9, PMEA_ASPFC ;  B8NPS7, PMEA_ASPFN ;
DR   Q4WBT5, PMEA_ASPFU ;  A2QK82, PMEA_ASPNC ;  Q2UBD9, PMEA_ASPOR ;
DR   P0C1A9, PMEA_DICD3 ;  Q5B7U0, PMEA_EMENI ;  P0C1A8, PMEA_ERWCH ;
DR   A1DBT4, PMEA_NEOFI ;  Q47474, PMEB_DICD3 ;  P55743, PMEB_PECCC ;
DR   Q43143, PMEU1_SOLLC;  P85076, PME_ACTDE  ;  Q12535, PME_ASPAC  ;
DR   P17872, PME_ASPTU  ;  Q42608, PME_BRACM  ;  P41510, PME_BRANA  ;
DR   P86075, PME_CAPAA  ;  P86085, PME_CAPCH  ;  P83218, PME_DAUCA  ;
DR   Q42920, PME_MEDSA  ;  Q43043, PME_PETIN  ;  Q43062, PME_PRUPE  ;
DR   Q84WM7, PPME1_ARATH;
//
ID   3.1.1.12
DE   Transferred entry: 3.1.1.1.
//
ID   3.1.1.13
DE   Sterol esterase.
AN   Cholesterol ester synthase.
AN   Cholesterol esterase.
AN   Triterpenol esterase.
CA   A steryl ester + H(2)O = a sterol + a fatty acid.
CC   -!- A group of enzymes of broad specificity, acting on esters of sterols
CC       and long-chain fatty acids, that may also bring about the
CC       esterification of sterols.
CC   -!- Activated by bile salts.
PR   PROSITE; PDOC00112;
DR   P30122, CEL_BOVIN  ;  P19835, CEL_HUMAN  ;  Q64285, CEL_MOUSE  ;
DR   P07882, CEL_RAT    ;  P38571, LICH_HUMAN ;  Q4R4S5, LICH_MACFA ;
DR   Q9Z0M5, LICH_MOUSE ;  Q64194, LICH_RAT   ;  P34163, TGL1_YEAST ;
DR   Q07804, YEH1_YEAST ;  Q07950, YEH2_YEAST ;
//
ID   3.1.1.14
DE   Chlorophyllase.
CA   Chlorophyll + H(2)O = phytol + chlorophyllide.
CC   -!- Chlorophyllase has been found in higher plants, diatoms, and in the
CC       green algae Chlorella.
CC   -!- Forms part of the chlorophyll degradation pathway and is thought to
CC       take part in de-greening processes such as fruit ripening, leaf
CC       senescence and flowering, as well as in the turnover and homeostasis
CC       of chlorophyll.
CC   -!- Acts preferentially on chlorophyll a but will also accept chlorophyll
CC       b and pheophytins as substrates.
CC   -!- Ethylene and methyl jasmonate, which are known to accelerate
CC       senescence in many species, can enhance the activity of the hormone-
CC       inducible form of this enzyme.
DR   Q9LE89, CLH0_CHEAL ;  O22527, CLH1_ARATH ;  P59677, CLH1_CHEAL ;
DR   Q9MV14, CLH1_CITSI ;  Q94LX1, CLH1_CITUN ;  Q9M7I7, CLH2_ARATH ;
DR   P59678, CLH2_CHEAL ;
//
ID   3.1.1.15
DE   L-arabinonolactonase.
CA   L-arabinono-1,4-lactone + H(2)O = L-arabinonate.
//
ID   3.1.1.16
DE   Transferred entry: 3.1.1.24 and 5.3.3.4.
//
ID   3.1.1.17
DE   Gluconolactonase.
AN   Aldonolactonase.
AN   Lactonase.
CA   D-glucono-1,5-lactone + H(2)O = D-gluconate.
CC   -!- Acts on a wide range of hexono-1,5-lactones.
CC   -!- Formerly EC 3.1.1.18.
DR   Q01578, GNL_ZYMMO  ;  Q9TTJ5, RGN_BOVIN  ;  Q9I923, RGN_CHICK  ;
DR   Q6TLF6, RGN_DANRE  ;  Q15493, RGN_HUMAN  ;  Q2PFX5, RGN_MACFA  ;
DR   Q64374, RGN_MOUSE  ;  Q06AA3, RGN_PIG    ;  Q5R837, RGN_PONAB  ;
DR   Q9TTJ6, RGN_RABIT  ;  Q03336, RGN_RAT    ;  Q9I922, RGN_XENLA  ;
DR   Q6DF62, RGN_XENTR  ;
//
ID   3.1.1.18
DE   Transferred entry: 3.1.1.17.
//
ID   3.1.1.19
DE   Uronolactonase.
CA   D-glucurono-6,2-lactone + H(2)O = D-glucuronate.
//
ID   3.1.1.20
DE   Tannase.
CA   Digallate + H(2)O = 2 gallate.
CC   -!- Also hydrolyzes ester links in other tannins.
DR   P78581, TAN_ASPOR  ;
//
ID   3.1.1.21
DE   Retinyl-palmitate esterase.
CA   Retinyl palmitate + H(2)O = retinol + palmitate.
DR   P50903, LIPP_CAVPO ;  P83629, LIPP_FELCA ;  P29183, LIPP_HORSE ;
DR   P16233, LIPP_HUMAN ;  Q6P8U6, LIPP_MOUSE ;  Q64425, LIPP_MYOCO ;
DR   P00591, LIPP_PIG   ;  Q02157, LIPP_RABIT ;  P27657, LIPP_RAT   ;
DR   O88354, LIPP_SPETR ;
//
ID   3.1.1.22
DE   Hydroxybutyrate-dimer hydrolase.
CA   (R)-3-((R)-3-hydroxybutanoyloxy)butanoate + H(2)O = 2 (R)-3-
CA   hydroxybutanoate.
DR   O05690, HBOH1_BURPI;  Q9X6X9, HBOH2_BURPI;  A1TRI4, HBOH_ACIAC ;
DR   A1KBP4, HBOH_AZOSB ;  Q1BYN6, HBOH_BURCA ;  A0K516, HBOH_BURCH ;
DR   Q0BHU5, HBOH_BURCM ;  A3MME1, HBOH_BURM7 ;  A2S9Q3, HBOH_BURM9 ;
DR   Q62I60, HBOH_BURMA ;  A1V1X3, HBOH_BURMS ;  A3NYK1, HBOH_BURP0 ;
DR   Q3JPD1, HBOH_BURP1 ;  A3NCT8, HBOH_BURP6 ;  Q63RF6, HBOH_BURPS ;
DR   Q39J35, HBOH_BURS3 ;  Q2SYN3, HBOH_BURTA ;  A4JBY8, HBOH_BURVG ;
DR   Q13Q76, HBOH_BURXL ;  Q0K9H3, HBOH_CUPNH ;  Q46ZT8, HBOH_CUPPJ ;
DR   A1TWS1, HBOH_MARAV ;  A1VUF3, HBOH_POLNA ;  Q122D1, HBOH_POLSJ ;
DR   Q1LLY7, HBOH_RALME ;  Q8XZR1, HBOH_RALSO ;  Q21U20, HBOH_RHOFD ;
//
ID   3.1.1.23
DE   Acylglycerol lipase.
AN   Monoacylglycerol lipase.
CA   Hydrolyzes glycerol monoesters of long-chain fatty acids.
DR   Q08DW9, ABD12_BOVIN;  Q5ZIN0, ABD12_CHICK;  Q08C93, ABD12_DANRE;
DR   Q8N2K0, ABD12_HUMAN;  Q4R766, ABD12_MACFA;  Q99LR1, ABD12_MOUSE;
DR   Q6AYT7, ABD12_RAT  ;  B4F753, ABD12_XENTR;  Q6GLL2, ABH6A_XENLA;
DR   Q7SY73, ABH6B_XENLA;  Q1LZ86, ABHD6_BOVIN;  Q9BV23, ABHD6_HUMAN;
DR   Q8R2Y0, ABHD6_MOUSE;  Q5XI64, ABHD6_RAT  ;  Q99685, MGLL_HUMAN ;
DR   O35678, MGLL_MOUSE ;  Q8R431, MGLL_RAT   ;  P82597, MGLP_BAC25 ;
//
ID   3.1.1.24
DE   3-oxoadipate enol-lactonase.
AN   3-ketoadipate enol-lactonase.
AN   3-oxoadipic enol-lactone hydrolase.
AN   Beta-ketoadipate enol-lactone hydrolase.
AN   Beta-ketoadipic enol-lactone hydrolase.
AN   Carboxymethylbutenolide lactonase.
CA   3-oxoadipate enol-lactone + H(2)O = 3-oxoadipate.
CC   -!- Acts on the product of EC 4.1.1.44.
CC   -!- Formerly EC 3.1.1.16.
DR   Q59093, ELH1_ACIAD ;  P00632, ELH2_ACIAD ;
//
ID   3.1.1.25
DE   1,4-lactonase.
AN   Gamma-lactonase.
CA   A 1,4-lactone + H(2)O = a 4-hydroxyacid.
CF   Calcium.
CC   -!- Specific for 1,4-lactones with 4-8 carbon atoms.
CC   -!- Does not hydrolyze simple aliphatic esters, acetylcholine, sugar
CC       lactones or substituted aliphatic lactones, e.g. 3-hydroxy-4-
CC       butyrolactone.
//
ID   3.1.1.26
DE   Galactolipase.
CA   1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H(2)O = 3-beta-D-
CA   galactosyl-sn-glycerol + 2 carboxylates.
CC   -!- Also acts on 2,3-di-O-acyl-1-O-(6-O-alpha-D-galactosyl-beta-D-
CC       galactosyl)-D-glycerol, and phosphatidylcholine and other
CC       phospholipids.
DR   A5PK46, LIPR2_BOVIN;  P81139, LIPR2_CAVPO;  P54317, LIPR2_HUMAN;
DR   P17892, LIPR2_MOUSE;  Q64424, LIPR2_MYOCO;  P54318, LIPR2_RAT  ;
DR   Q9MA46, PLA12_ARATH;
//
ID   3.1.1.27
DE   4-pyridoxolactonase.
CA   4-pyridoxolactone + H(2)O = 4-pyridoxate.
DR   Q988B9, PDLA_RHILO ;
//
ID   3.1.1.28
DE   Acylcarnitine hydrolase.
CA   O-acylcarnitine + H(2)O = a fatty acid + L-carnitine.
CC   -!- Acts on higher fatty acid (C(6) to C(18)) esters of L-carnitine.
CC   -!- Highest activity is with O-decanoyl-L-carnitine.
//
ID   3.1.1.29
DE   Aminoacyl-tRNA hydrolase.
AN   Peptidyl-tRNA hydrolase.
CA   N-substituted aminoacyl-tRNA + H(2)O = N-substituted amino acid + tRNA.
PR   PROSITE; PDOC00920;
DR   D2HD32, ICT1_AILME ;  Q3T116, ICT1_BOVIN ;  Q14197, ICT1_HUMAN ;
DR   Q8R035, ICT1_MOUSE ;  B5XAM2, ICT1_SALSA ;  Q8NRV3, PTH1_CORGL ;
DR   Q4JU39, PTH1_CORJK ;  Q3ZBL5, PTH2_BOVIN ;  O76387, PTH2_CAEEL ;
DR   Q8NRV6, PTH2_CORGL ;  Q4JU38, PTH2_CORJK ;  Q54ZD0, PTH2_DICDI ;
DR   O97067, PTH2_DROME ;  Q9Y3E5, PTH2_HUMAN ;  Q8R2Y8, PTH2_MOUSE ;
DR   O13830, PTH2_SCHPO ;  P34222, PTH2_YEAST ;  Q8GW64, PTHC_ARATH ;
DR   Q6NLS8, PTHM_ARATH ;  Q5N9Q7, PTHM_ORYSJ ;  A9NE82, PTH_ACHLI  ;
DR   A1TT75, PTH_ACIAC  ;  Q6F8I7, PTH_ACIAD  ;  B7GYR0, PTH_ACIB3  ;
DR   B7I7B5, PTH_ACIB5  ;  B2HUM2, PTH_ACIBC  ;  Q1IHW2, PTH_ACIBL  ;
DR   B0VTX2, PTH_ACIBS  ;  B0V8G0, PTH_ACIBY  ;  C1F905, PTH_ACIC5  ;
DR   A5FZ48, PTH_ACICJ  ;  B9ME46, PTH_ACIET  ;  B7J502, PTH_ACIF2  ;
DR   B5EKJ0, PTH_ACIF5  ;  A1W4G0, PTH_ACISJ  ;  A3MYA5, PTH_ACTP2  ;
DR   B3GZM3, PTH_ACTP7  ;  B0BRJ2, PTH_ACTPJ  ;  A6VP74, PTH_ACTSZ  ;
DR   A0KN04, PTH_AERHH  ;  Q9YBD6, PTH_AERPE  ;  B9J795, PTH_AGRRK  ;
DR   Q8UD97, PTH_AGRT5  ;  B9JZ39, PTH_AGRVS  ;  B2UPQ2, PTH_AKKM8  ;
DR   Q0VS84, PTH_ALCBS  ;  Q0ABZ7, PTH_ALHEH  ;  B6EHH0, PTH_ALISL  ;
DR   A6TJM7, PTH_ALKMQ  ;  A8MK43, PTH_ALKOO  ;  B4RT72, PTH_ALTMD  ;
DR   B3ESC6, PTH_AMOA5  ;  B8J804, PTH_ANAD2  ;  Q2IM62, PTH_ANADE  ;
DR   A7H6J5, PTH_ANADF  ;  B9KHC6, PTH_ANAMF  ;  Q5P9A6, PTH_ANAMM  ;
DR   Q2GII6, PTH_ANAPZ  ;  B4ULC2, PTH_ANASK  ;  B9MPK0, PTH_ANATD  ;
DR   Q3M4P0, PTH_ANAVT  ;  O66677, PTH_AQUAE  ;  A8ESI0, PTH_ARCB4  ;
DR   O28185, PTH_ARCFU  ;  Q5P722, PTH_AROAE  ;  A1R4G4, PTH_ARTAT  ;
DR   B8HFE2, PTH_ARTCA  ;  A0JU94, PTH_ARTS2  ;  Q2NIQ9, PTH_AYWBP  ;
DR   A8HS70, PTH_AZOC5  ;  B6YQC2, PTH_AZOPC  ;  A1K3G5, PTH_AZOSB  ;
DR   C1DEV7, PTH_AZOVD  ;  A7Z0H6, PTH_BACA2  ;  Q81VY9, PTH_BACAN  ;
DR   Q73FF7, PTH_BACC1  ;  A7GJW3, PTH_BACCN  ;  B9IZD4, PTH_BACCQ  ;
DR   Q81J96, PTH_BACCR  ;  Q63HI2, PTH_BACCZ  ;  Q5LG56, PTH_BACFN  ;
DR   Q64X30, PTH_BACFR  ;  Q9KGJ3, PTH_BACHD  ;  Q6HPW6, PTH_BACHK  ;
DR   Q65PG8, PTH_BACLD  ;  A8F920, PTH_BACP2  ;  Q5WAD6, PTH_BACSK  ;
DR   P37470, PTH_BACSU  ;  Q89YZ2, PTH_BACTN  ;  A6L6X1, PTH_BACV8  ;
DR   A1UTH5, PTH_BARBK  ;  Q6G2L1, PTH_BARHE  ;  Q6G0F9, PTH_BARQU  ;
DR   A9IR82, PTH_BART1  ;  Q1LTH1, PTH_BAUCH  ;  Q6MJR3, PTH_BDEBA  ;
DR   B2IG63, PTH_BEII9  ;  B8DTI5, PTH_BIFA0  ;  A1A141, PTH_BIFAA  ;
DR   B3DSV5, PTH_BIFLD  ;  Q8G5I6, PTH_BIFLO  ;  B7GTK5, PTH_BIFLS  ;
DR   Q2KY99, PTH_BORA1  ;  Q0SM65, PTH_BORAP  ;  Q7WNY2, PTH_BORBR  ;
DR   P47714, PTH_BORBU  ;  B7J0N3, PTH_BORBZ  ;  B5RMX9, PTH_BORDL  ;
DR   Q65ZY7, PTH_BORGA  ;  B2S1C9, PTH_BORHD  ;  Q7W179, PTH_BORPA  ;
DR   A9I6W1, PTH_BORPD  ;  Q7VUH3, PTH_BORPE  ;  B5RQC4, PTH_BORRA  ;
DR   A1R0L0, PTH_BORT9  ;  Q89DJ9, PTH_BRAJA  ;  A5ECT2, PTH_BRASB  ;
DR   A4Z0I5, PTH_BRASO  ;  C0ZHD7, PTH_BREBN  ;  Q2YLX5, PTH_BRUA2  ;
DR   Q9AEQ5, PTH_BRUAB  ;  A9M6K1, PTH_BRUC2  ;  C0REH2, PTH_BRUMB  ;
DR   P65863, PTH_BRUME  ;  A5VRR6, PTH_BRUO2  ;  B0CHX5, PTH_BRUSI  ;
DR   P65864, PTH_BRUSU  ;  B8D8Y9, PTH_BUCA5  ;  P57287, PTH_BUCAI  ;
DR   Q8K9V3, PTH_BUCAP  ;  P59490, PTH_BUCBP  ;  Q057V0, PTH_BUCCC  ;
DR   B1YN54, PTH_BURA4  ;  Q1BTG4, PTH_BURCA  ;  B1JYQ1, PTH_BURCC  ;
DR   A0KAM7, PTH_BURCH  ;  B4EAR1, PTH_BURCJ  ;  Q0BBQ3, PTH_BURCM  ;
DR   A9AEY6, PTH_BURM1  ;  A3MQB3, PTH_BURM7  ;  A2S6B4, PTH_BURM9  ;
DR   Q62FC1, PTH_BURMA  ;  A1UZN8, PTH_BURMS  ;  A3NR95, PTH_BURP0  ;
DR   Q3JW88, PTH_BURP1  ;  A3N5J9, PTH_BURP6  ;  B2JCN7, PTH_BURP8  ;
DR   B2SXG3, PTH_BURPP  ;  Q63XM0, PTH_BURPS  ;  Q39CT8, PTH_BURS3  ;
DR   Q2T1B9, PTH_BURTA  ;  Q145X4, PTH_BURXL  ;  A8MBW8, PTH_CALMQ  ;
DR   A4XIS3, PTH_CALS8  ;  A7ZCE9, PTH_CAMC1  ;  A7H088, PTH_CAMC5  ;
DR   A0RMV6, PTH_CAMFF  ;  A7I2W3, PTH_CAMHC  ;  A8FKA1, PTH_CAMJ8  ;
DR   A7H563, PTH_CAMJD  ;  Q9PII7, PTH_CAMJE  ;  A1VY31, PTH_CAMJJ  ;
DR   Q5HWF9, PTH_CAMJR  ;  B9KDP1, PTH_CAMLR  ;  Q9F8Q3, PTH_CARHZ  ;
DR   B8GZU8, PTH_CAUCN  ;  Q9AAV9, PTH_CAUCR  ;  A9WBS1, PTH_CHLAA  ;
DR   Q5L564, PTH_CHLAB  ;  B8G3X3, PTH_CHLAD  ;  Q3ARM4, PTH_CHLCH  ;
DR   Q821W6, PTH_CHLCV  ;  Q255S1, PTH_CHLFF  ;  B3ECG5, PTH_CHLL2  ;
DR   P49607, PTH_CHLMU  ;  B3QP08, PTH_CHLP8  ;  B3EQK4, PTH_CHLPB  ;
DR   A1BGB1, PTH_CHLPD  ;  Q9Z6V6, PTH_CHLPN  ;  B9LE93, PTH_CHLSY  ;
DR   B0B927, PTH_CHLT2  ;  Q3KKP1, PTH_CHLTA  ;  B0BAQ6, PTH_CHLTB  ;
DR   Q8KD05, PTH_CHLTE  ;  O84806, PTH_CHLTR  ;  Q1QXD3, PTH_CHRSD  ;
DR   Q7NQT1, PTH_CHRVO  ;  A8AFY6, PTH_CITK8  ;  Q97E97, PTH_CLOAB  ;
DR   A7FPJ7, PTH_CLOB1  ;  C3KW96, PTH_CLOB6  ;  A6LPJ5, PTH_CLOB8  ;
DR   B2UXS9, PTH_CLOBA  ;  B2TI10, PTH_CLOBB  ;  A5I7R5, PTH_CLOBH  ;
DR   C1FNE6, PTH_CLOBJ  ;  B1IGZ7, PTH_CLOBK  ;  A7GJD4, PTH_CLOBL  ;
DR   B1KTE2, PTH_CLOBM  ;  Q181A2, PTH_CLOD6  ;  B9DY52, PTH_CLOK1  ;
DR   A5N4J0, PTH_CLOK5  ;  A0PXL3, PTH_CLONN  ;  Q0TMG7, PTH_CLOP1  ;
DR   Q8XHJ8, PTH_CLOPE  ;  A9KR32, PTH_CLOPH  ;  Q0SQ66, PTH_CLOPS  ;
DR   Q899I4, PTH_CLOTE  ;  Q47Y87, PTH_COLP3  ;  B5Y8L1, PTH_COPPD  ;
DR   Q6NI78, PTH_CORDI  ;  Q8FQV6, PTH_COREF  ;  B6J9D9, PTH_COXB1  ;
DR   B6J330, PTH_COXB2  ;  A9KF13, PTH_COXBN  ;  A9NAT7, PTH_COXBR  ;
DR   Q83AP0, PTH_COXBU  ;  Q0KEQ0, PTH_CUPNH  ;  Q476G1, PTH_CUPPJ  ;
DR   B2AGT6, PTH_CUPTR  ;  Q11RT7, PTH_CYTH3  ;  Q479M0, PTH_DECAR  ;
DR   Q3Z8W2, PTH_DEHE1  ;  A5FRL3, PTH_DEHSB  ;  Q3ZX09, PTH_DEHSC  ;
DR   C1CXT2, PTH_DEIDV  ;  Q1IWN4, PTH_DEIGD  ;  Q9RRW3, PTH_DEIRA  ;
DR   A9BP19, PTH_DELAS  ;  C6C0N2, PTH_DESAD  ;  B1I197, PTH_DESAP  ;
DR   B8J0S9, PTH_DESDA  ;  Q30ZH1, PTH_DESDG  ;  B8FZA5, PTH_DESHD  ;
DR   Q251S4, PTH_DESHY  ;  C4XHR2, PTH_DESMR  ;  Q6AJL9, PTH_DESPS  ;
DR   A4J0Q6, PTH_DESRM  ;  Q72BR1, PTH_DESVH  ;  B8DKL7, PTH_DESVM  ;
DR   A1VDR1, PTH_DESVV  ;  A5EWU9, PTH_DICNV  ;  A8LRY5, PTH_DINSH  ;
DR   A7ZKX7, PTH_ECO24  ;  B7UQ92, PTH_ECO27  ;  B7MKA6, PTH_ECO45  ;
DR   B7LGW4, PTH_ECO55  ;  P0A7D3, PTH_ECO57  ;  B5YXM2, PTH_ECO5E  ;
DR   B7NUX0, PTH_ECO7I  ;  B7MTY8, PTH_ECO81  ;  B7LXB9, PTH_ECO8A  ;
DR   C4ZTP5, PTH_ECOBW  ;  B1XAP5, PTH_ECODH  ;  A7ZZE0, PTH_ECOHS  ;
DR   Q0TIG6, PTH_ECOL5  ;  P0A7D2, PTH_ECOL6  ;  B1IU89, PTH_ECOLC  ;
DR   P0A7D1, PTH_ECOLI  ;  B7N415, PTH_ECOLU  ;  B6I9R9, PTH_ECOSE  ;
DR   B1LH96, PTH_ECOSM  ;  Q1RCN4, PTH_ECOUT  ;  C5B806, PTH_EDWI9  ;
DR   Q3YT13, PTH_EHRCJ  ;  Q2GHW4, PTH_EHRCR  ;  Q5FFA3, PTH_EHRRG  ;
DR   Q5HC85, PTH_EHRRW  ;  B2KE94, PTH_ELUMP  ;  A4WBD3, PTH_ENT38  ;
DR   Q839C0, PTH_ENTFA  ;  A7MNK0, PTH_ENTS8  ;  Q6D557, PTH_ERWCT  ;
DR   B2VEI9, PTH_ERWT9  ;  Q2NAN2, PTH_ERYLH  ;  B7LSI6, PTH_ESCF3  ;
DR   C4Z4L5, PTH_EUBE2  ;  C4ZBV8, PTH_EUBR3  ;  B1YGP7, PTH_EXIS2  ;
DR   C4KZU9, PTH_EXISA  ;  A7HKM4, PTH_FERNB  ;  B0S0D9, PTH_FINM2  ;
DR   Q0RCD6, PTH_FRAAA  ;  B0TZF5, PTH_FRAP2  ;  Q2J5Z1, PTH_FRASC  ;
DR   Q14IE8, PTH_FRAT1  ;  A7NBY0, PTH_FRATF  ;  Q2A3N5, PTH_FRATH  ;
DR   B2SH51, PTH_FRATM  ;  A0Q6M6, PTH_FRATN  ;  Q0BM46, PTH_FRATO  ;
DR   Q5NGZ6, PTH_FRATT  ;  A4IY63, PTH_FRATW  ;  Q8RIJ5, PTH_FUSNN  ;
DR   C1A7P9, PTH_GEMAT  ;  B5EHX1, PTH_GEOBB  ;  Q5L3U7, PTH_GEOKA  ;
DR   B3E6F9, PTH_GEOLS  ;  Q39RR0, PTH_GEOMG  ;  B9M5U5, PTH_GEOSF  ;
DR   Q74FE6, PTH_GEOSL  ;  C6E501, PTH_GEOSM  ;  C5D374, PTH_GEOSW  ;
DR   A4IJC9, PTH_GEOTN  ;  A5G7R5, PTH_GEOUR  ;  Q7NN75, PTH_GLOVI  ;
DR   Q5FRT7, PTH_GLUOX  ;  Q0BPN7, PTH_GRABC  ;  Q7VMI1, PTH_HAEDU  ;
DR   Q4QNE8, PTH_HAEI8  ;  A5UGR0, PTH_HAEIG  ;  P44682, PTH_HAEIN  ;
DR   B8F503, PTH_HAEPS  ;  Q0I248, PTH_HAES1  ;  B0UVY6, PTH_HAES2  ;
DR   Q2SLA3, PTH_HAHCH  ;  A1WVQ1, PTH_HALHL  ;  B9LTP1, PTH_HALLT  ;
DR   Q5V1D3, PTH_HALMA  ;  B0R2Y5, PTH_HALS3  ;  P61414, PTH_HALSA  ;
DR   Q18KN8, PTH_HALWD  ;  Q17V73, PTH_HELAH  ;  Q7VG29, PTH_HELHP  ;
DR   B6JNZ5, PTH_HELP2  ;  B5Z9B6, PTH_HELPG  ;  Q1CRD9, PTH_HELPH  ;
DR   Q9ZJC3, PTH_HELPJ  ;  B2UVP3, PTH_HELPS  ;  P56077, PTH_HELPY  ;
DR   A9B7I9, PTH_HERA2  ;  Q86Y79, PTH_HUMAN  ;  B4U930, PTH_HYDS0  ;
DR   Q0C2D0, PTH_HYPNA  ;  Q5QV03, PTH_IDILO  ;  Q28LA3, PTH_JANSC  ;
DR   A6W6V3, PTH_KINRD  ;  B5XW43, PTH_KLEP3  ;  A6TAP7, PTH_KLEP7  ;
DR   C5CFR9, PTH_KOSOT  ;  Q5FMA9, PTH_LACAC  ;  Q03SZ9, PTH_LACBA  ;
DR   Q034V1, PTH_LACC3  ;  B3WAP7, PTH_LACCB  ;  Q1GBP4, PTH_LACDA  ;
DR   Q04C43, PTH_LACDB  ;  B2GA68, PTH_LACF3  ;  Q046E4, PTH_LACGA  ;
DR   A8YXI6, PTH_LACH4  ;  Q74LA8, PTH_LACJO  ;  Q9CJI1, PTH_LACLA  ;
DR   A2RH85, PTH_LACLM  ;  Q033H5, PTH_LACLS  ;  Q88Z39, PTH_LACPL  ;
DR   A5VI57, PTH_LACRD  ;  B2G5N5, PTH_LACRJ  ;  Q1WSG3, PTH_LACS1  ;
DR   O85235, PTH_LACSK  ;  Q38V72, PTH_LACSS  ;  C1DBA8, PTH_LARHH  ;
DR   Q1MQD5, PTH_LAWIP  ;  Q5X1N7, PTH_LEGPA  ;  A5IAS3, PTH_LEGPC  ;
DR   Q5ZS66, PTH_LEGPH  ;  Q5WTE7, PTH_LEGPL  ;  Q6ADQ8, PTH_LEIXX  ;
DR   Q04TA4, PTH_LEPBJ  ;  Q051M6, PTH_LEPBL  ;  B1Y3Q1, PTH_LEPCP  ;
DR   Q72RZ0, PTH_LEPIC  ;  Q8F3Q2, PTH_LEPIN  ;  Q03Z52, PTH_LEUMM  ;
DR   Q92F62, PTH_LISIN  ;  C1KYE6, PTH_LISMC  ;  Q724K0, PTH_LISMF  ;
DR   B8DGL2, PTH_LISMH  ;  Q8YAD1, PTH_LISMO  ;  A0AF11, PTH_LISW6  ;
DR   B9E8U9, PTH_MACCJ  ;  Q2VZ24, PTH_MAGSA  ;  Q65V47, PTH_MANSM  ;
DR   A1U374, PTH_MARAV  ;  Q0ARN8, PTH_MARMM  ;  A6W1C9, PTH_MARMS  ;
DR   Q6F240, PTH_MESFL  ;  Q11GC5, PTH_MESSB  ;  A6UWF5, PTH_META3  ;
DR   Q8TKX4, PTH_METAC  ;  Q466V4, PTH_METBF  ;  Q12WH8, PTH_METBU  ;
DR   B7KNU7, PTH_METC4  ;  Q60A14, PTH_METCA  ;  A9W5L3, PTH_METEP  ;
DR   Q1H3J3, PTH_METFK  ;  B3E0Q7, PTH_METI4  ;  Q60363, PTH_METJA  ;
DR   Q8TV04, PTH_METKA  ;  A4FYL9, PTH_METM5  ;  A9A6B6, PTH_METM6  ;
DR   A6VJR3, PTH_METM7  ;  Q8Q0M4, PTH_METMA  ;  P61234, PTH_METMP  ;
DR   B8IFN4, PTH_METNO  ;  B1Z9F8, PTH_METPB  ;  A2SKU1, PTH_METPP  ;
DR   B1M1C0, PTH_METRJ  ;  B0UGY2, PTH_METS4  ;  A4YD82, PTH_METS5  ;
DR   B8EK40, PTH_METSB  ;  O27732, PTH_METTH  ;  A6USA3, PTH_METVS  ;
DR   Q2RMC1, PTH_MOOTA  ;  Q8BW00, PTH_MOUSE  ;  A0QBW3, PTH_MYCA1  ;
DR   B3PNH1, PTH_MYCA5  ;  B1MKD8, PTH_MYCA9  ;  A5IZI8, PTH_MYCAP  ;
DR   P65866, PTH_MYCBO  ;  A1KHF2, PTH_MYCBP  ;  C1AM05, PTH_MYCBT  ;
DR   Q2ST16, PTH_MYCCT  ;  Q8RLD7, PTH_MYCGA  ;  P47329, PTH_MYCGE  ;
DR   A4T6N5, PTH_MYCGI  ;  Q601M5, PTH_MYCH2  ;  Q4A8G1, PTH_MYCH7  ;
DR   Q4AAD0, PTH_MYCHJ  ;  B8ZU62, PTH_MYCLB  ;  Q9CD49, PTH_MYCLE  ;
DR   B2HDJ5, PTH_MYCMM  ;  Q6KHA3, PTH_MYCMO  ;  Q6MS28, PTH_MYCMS  ;
DR   Q741V9, PTH_MYCPA  ;  Q8EWQ8, PTH_MYCPE  ;  P78034, PTH_MYCPN  ;
DR   Q98PE2, PTH_MYCPU  ;  A0R3D3, PTH_MYCS2  ;  Q4A5E8, PTH_MYCS5  ;
DR   A3Q5H1, PTH_MYCSJ  ;  A1UL23, PTH_MYCSK  ;  Q1B425, PTH_MYCSS  ;
DR   A5U157, PTH_MYCTA  ;  P65865, PTH_MYCTU  ;  A0PW66, PTH_MYCUA  ;
DR   A1TEG1, PTH_MYCVP  ;  Q1D292, PTH_MYXXD  ;  P61235, PTH_NANEQ  ;
DR   Q5F9L4, PTH_NEIG1  ;  B4RK78, PTH_NEIG2  ;  A9M3M7, PTH_NEIM0  ;
DR   Q9JV42, PTH_NEIMA  ;  Q9K029, PTH_NEIMB  ;  A1KT53, PTH_NEIMF  ;
DR   Q2GE99, PTH_NEOSM  ;  Q0AGY5, PTH_NITEC  ;  Q82TQ6, PTH_NITEU  ;
DR   Q1QIV8, PTH_NITHX  ;  Q2YBH2, PTH_NITMU  ;  Q3JDQ7, PTH_NITOC  ;
DR   Q3SPM7, PTH_NITWN  ;  Q5YPZ6, PTH_NOCFA  ;  B2JA15, PTH_NOSP7  ;
DR   Q8YYK4, PTH_NOSS1  ;  Q2G6G8, PTH_NOVAD  ;  Q8CXP8, PTH_OCEIH  ;
DR   B6JIP3, PTH_OLICO  ;  Q6YR64, PTH_ONYPE  ;  A6L8V3, PTH_PARD8  ;
DR   A1B1H5, PTH_PARDP  ;  A7HVD7, PTH_PARL1  ;  P57820, PTH_PASMU  ;
DR   C6DHY7, PTH_PECCP  ;  Q03DZ8, PTH_PEDPA  ;  Q3A314, PTH_PELCD  ;
DR   Q3B3L6, PTH_PELLD  ;  B4SGM1, PTH_PELPB  ;  A1AM05, PTH_PELPD  ;
DR   Q4FPG9, PTH_PELUB  ;  C0QQW6, PTH_PERMH  ;  B4R8Q8, PTH_PHEZH  ;
DR   Q7N5A1, PTH_PHOLL  ;  Q6LNA9, PTH_PHOPR  ;  B1VAH1, PTH_PHYAS  ;
DR   B3QZM3, PTH_PHYMT  ;  B1XS66, PTH_POLNS  ;  Q12E01, PTH_POLSJ  ;
DR   A4T070, PTH_POLSQ  ;  B2RHF2, PTH_PORG3  ;  Q7MXK9, PTH_PORGI  ;
DR   B4S8L3, PTH_PROA2  ;  Q6AAC7, PTH_PROAC  ;  A3PAX1, PTH_PROM0  ;
DR   A2C082, PTH_PROM1  ;  A8G2Q9, PTH_PROM2  ;  A2CCI1, PTH_PROM3  ;
DR   A2BUN1, PTH_PROM5  ;  Q31CT2, PTH_PROM9  ;  Q7VDT7, PTH_PROMA  ;
DR   B4EVR1, PTH_PROMH  ;  Q7V4V4, PTH_PROMM  ;  Q7V342, PTH_PROMP  ;
DR   A2BP49, PTH_PROMS  ;  Q46HC4, PTH_PROMT  ;  A4SE63, PTH_PROVI  ;
DR   Q48MW1, PTH_PSE14  ;  Q15SQ2, PTH_PSEA6  ;  A6VC68, PTH_PSEA7  ;
DR   B7V0L8, PTH_PSEA8  ;  Q02G02, PTH_PSEAB  ;  Q9HVC3, PTH_PSEAE  ;
DR   Q1IEY8, PTH_PSEE4  ;  Q4K688, PTH_PSEF5  ;  C3KCR9, PTH_PSEFS  ;
DR   Q3IK86, PTH_PSEHT  ;  A4XR54, PTH_PSEMY  ;  A5VYF8, PTH_PSEP1  ;
DR   Q3K6W2, PTH_PSEPF  ;  B0KND4, PTH_PSEPG  ;  Q88PX8, PTH_PSEPK  ;
DR   B1JEQ3, PTH_PSEPW  ;  Q888C8, PTH_PSESM  ;  Q4ZXX4, PTH_PSEU2  ;
DR   Q4FVB5, PTH_PSYA2  ;  Q1QED6, PTH_PSYCK  ;  A1STD6, PTH_PSYIN  ;
DR   Q9V108, PTH_PYRAB  ;  Q8ZYM4, PTH_PYRAE  ;  Q8U0N0, PTH_PYRFU  ;
DR   O74017, PTH_PYRHO  ;  Q5JDB8, PTH_PYRKO  ;  Q1LRQ3, PTH_RALME  ;
DR   B2UER4, PTH_RALPJ  ;  Q8Y2E3, PTH_RALSO  ;  A9WU36, PTH_RENSM  ;
DR   B3PV10, PTH_RHIE6  ;  Q2K5U1, PTH_RHIEC  ;  Q1MDL5, PTH_RHIL3  ;
DR   Q98HV6, PTH_RHILO  ;  B5ZY55, PTH_RHILW  ;  Q92N67, PTH_RHIME  ;
DR   C3MFM4, PTH_RHISN  ;  Q7UKV0, PTH_RHOBA  ;  B6ITK3, PTH_RHOCS  ;
DR   C1A349, PTH_RHOE4  ;  Q21XW1, PTH_RHOFD  ;  C1AY15, PTH_RHOOB  ;
DR   Q2ISF8, PTH_RHOP2  ;  Q07RP6, PTH_RHOP5  ;  Q6N1P9, PTH_RHOPA  ;
DR   Q219F8, PTH_RHOPB  ;  Q131M0, PTH_RHOPS  ;  B3Q7X3, PTH_RHOPT  ;
DR   Q2RMV4, PTH_RHORT  ;  A3PML9, PTH_RHOS1  ;  Q3IZN0, PTH_RHOS4  ;
DR   A4WPE4, PTH_RHOS5  ;  B9KMG1, PTH_RHOSK  ;  Q0S4R3, PTH_RHOSR  ;
DR   C3PP46, PTH_RICAE  ;  A8GP84, PTH_RICAH  ;  A8GVL6, PTH_RICB8  ;
DR   Q1RI72, PTH_RICBR  ;  A8EY65, PTH_RICCK  ;  Q92H41, PTH_RICCN  ;
DR   Q4UMK4, PTH_RICFE  ;  Q9ZCV4, PTH_RICPR  ;  C4K1L4, PTH_RICPU  ;
DR   B0BUI6, PTH_RICRO  ;  A8GSZ4, PTH_RICRS  ;  Q68WD4, PTH_RICTY  ;
DR   A7NK01, PTH_ROSCS  ;  Q161I4, PTH_ROSDO  ;  A5US07, PTH_ROSS1  ;
DR   Q1AXL4, PTH_RUBXD  ;  A1AXW5, PTH_RUTMC  ;  Q21FL6, PTH_SACD2  ;
DR   B5F4G7, PTH_SALA4  ;  Q57NM8, PTH_SALCH  ;  B5FU10, PTH_SALDC  ;
DR   B5R3J2, PTH_SALEP  ;  B5R917, PTH_SALG2  ;  B4TKB3, PTH_SALHS  ;
DR   B4SUH1, PTH_SALNS  ;  Q5PCR7, PTH_SALPA  ;  A9MVZ4, PTH_SALPB  ;
DR   Q2S4D2, PTH_SALRD  ;  B4TXV1, PTH_SALSV  ;  P0A282, PTH_SALTI  ;
DR   P0A281, PTH_SALTY  ;  O74806, PTH_SCHPO  ;  A8GD97, PTH_SERP5  ;
DR   A1S8R8, PTH_SHEAM  ;  B8E6L3, PTH_SHEB2  ;  A3D7M5, PTH_SHEB5  ;
DR   A6WRI8, PTH_SHEB8  ;  A9KZZ0, PTH_SHEB9  ;  Q12R19, PTH_SHEDO  ;
DR   Q087J1, PTH_SHEFN  ;  B0TR35, PTH_SHEHH  ;  A3QH38, PTH_SHELP  ;
DR   Q8EHN5, PTH_SHEON  ;  A4Y9D9, PTH_SHEPC  ;  A0KTX7, PTH_SHESA  ;
DR   A8FYZ9, PTH_SHESH  ;  Q0HLI0, PTH_SHESM  ;  Q0HXT4, PTH_SHESR  ;
DR   B1KDV1, PTH_SHEWM  ;  B2TZV2, PTH_SHIB3  ;  Q31ZP7, PTH_SHIBS  ;
DR   Q32H03, PTH_SHIDS  ;  Q0T5J1, PTH_SHIF8  ;  Q83LE1, PTH_SHIFL  ;
DR   Q3Z0S2, PTH_SHISS  ;  Q5LV91, PTH_SILPO  ;  Q1GK69, PTH_SILST  ;
DR   Q2NRR9, PTH_SODGM  ;  Q01QR3, PTH_SOLUE  ;  A9GXK1, PTH_SORC5  ;
DR   Q1GSP1, PTH_SPHAL  ;  A5V626, PTH_SPHWW  ;  A7WYQ5, PTH_STAA1  ;
DR   A6TYX7, PTH_STAA2  ;  Q2FJD9, PTH_STAA3  ;  Q2G0R9, PTH_STAA8  ;
DR   A5IQ55, PTH_STAA9  ;  Q2YVY3, PTH_STAAB  ;  Q5HIH3, PTH_STAAC  ;
DR   A6QEF5, PTH_STAAE  ;  P65867, PTH_STAAM  ;  P65868, PTH_STAAN  ;
DR   Q6GJG9, PTH_STAAR  ;  Q6GBY6, PTH_STAAS  ;  A8Z0Z1, PTH_STAAT  ;
DR   Q6YP15, PTH_STAAU  ;  P65869, PTH_STAAW  ;  B9DLD9, PTH_STACT  ;
DR   Q5HRQ3, PTH_STAEQ  ;  Q8CQU9, PTH_STAES  ;  Q4L3F9, PTH_STAHJ  ;
DR   A3DMF7, PTH_STAMF  ;  Q49V11, PTH_STAS1  ;  Q3K419, PTH_STRA1  ;
DR   Q8E7Y8, PTH_STRA3  ;  Q8E2I1, PTH_STRA5  ;  Q82HE5, PTH_STRAW  ;
DR   Q9K3T8, PTH_STRCO  ;  C0M9G4, PTH_STRE4  ;  B4U5H3, PTH_STREM  ;
DR   A8B006, PTH_STRGC  ;  B4SKT5, PTH_STRM5  ;  B2FQ21, PTH_STRMK  ;
DR   Q8DWN5, PTH_STRMU  ;  Q9A206, PTH_STRP1  ;  Q04N59, PTH_STRP2  ;
DR   P0DD50, PTH_STRP3  ;  B5E572, PTH_STRP4  ;  Q5XEM3, PTH_STRP6  ;
DR   C1C986, PTH_STRP7  ;  Q8P327, PTH_STRP8  ;  Q1JEA1, PTH_STRPB  ;
DR   Q1JP56, PTH_STRPC  ;  Q1JJA3, PTH_STRPD  ;  Q1J956, PTH_STRPF  ;
DR   A2RBX7, PTH_STRPG  ;  B1I6X7, PTH_STRPI  ;  B8ZJI3, PTH_STRPJ  ;
DR   Q48VW8, PTH_STRPM  ;  Q97TD1, PTH_STRPN  ;  P0DD51, PTH_STRPQ  ;
DR   B2IQZ3, PTH_STRPS  ;  B5XIP6, PTH_STRPZ  ;  Q8DRQ2, PTH_STRR6  ;
DR   A4VYI0, PTH_STRS2  ;  C0MC67, PTH_STRS7  ;  A3CJX1, PTH_STRSV  ;
DR   A4VS92, PTH_STRSY  ;  Q5M222, PTH_STRT1  ;  Q5M6L4, PTH_STRT2  ;
DR   Q03N21, PTH_STRTD  ;  B9DSP2, PTH_STRU0  ;  C1CH85, PTH_STRZJ  ;
DR   C1CN70, PTH_STRZP  ;  C1CNN8, PTH_STRZT  ;  Q877G5, PTH_SULAC  ;
DR   Q30TD4, PTH_SULDN  ;  C3MZS7, PTH_SULIA  ;  C4KJ09, PTH_SULIK  ;
DR   C3MJ30, PTH_SULIL  ;  C3MYS2, PTH_SULIM  ;  C3NF60, PTH_SULIN  ;
DR   C3N851, PTH_SULIY  ;  A6QBZ2, PTH_SULNB  ;  Q980V1, PTH_SULSO  ;
DR   B2V6V4, PTH_SULSY  ;  Q976I0, PTH_SULTO  ;  Q67JD0, PTH_SYMTH  ;
DR   Q2LUK5, PTH_SYNAS  ;  Q31RR0, PTH_SYNE7  ;  Q2JV16, PTH_SYNJA  ;
DR   Q2JNF7, PTH_SYNJB  ;  Q5N2J4, PTH_SYNP6  ;  Q7U9I5, PTH_SYNPX  ;
DR   Q0IDC6, PTH_SYNS3  ;  Q3AUQ0, PTH_SYNS9  ;  Q3AMZ1, PTH_SYNSC  ;
DR   Q0B0S6, PTH_SYNWW  ;  Q59989, PTH_SYNY3  ;  C5BT03, PTH_TERTT  ;
DR   Q9HLW6, PTH_THEAC  ;  Q8DJ45, PTH_THEEB  ;  Q47SW2, PTH_THEFY  ;
DR   A8F4D7, PTH_THELT  ;  Q9X1W1, PTH_THEMA  ;  B9K7S5, PTH_THENN  ;
DR   B6YTE3, PTH_THEON  ;  A5ILV6, PTH_THEP1  ;  B0KBG1, PTH_THEP3  ;
DR   B0K466, PTH_THEPX  ;  C6A1K8, PTH_THESM  ;  B1LBD6, PTH_THESQ  ;
DR   Q72IA8, PTH_THET2  ;  Q5SHZ2, PTH_THET8  ;  Q8R757, PTH_THETN  ;
DR   Q97CB4, PTH_THEVO  ;  B5YG54, PTH_THEYD  ;  Q31IN3, PTH_THICR  ;
DR   Q3SLR3, PTH_THIDA  ;  C4L932, PTH_TOLAT  ;  Q73Q01, PTH_TREDE  ;
DR   O83975, PTH_TREPA  ;  B2S4P8, PTH_TREPS  ;  Q110N1, PTH_TRIEI  ;
DR   Q83HD8, PTH_TROW8  ;  Q83FR1, PTH_TROWT  ;  B1AI63, PTH_UREP2  ;
DR   Q9PR67, PTH_UREPA  ;  B5ZAQ7, PTH_UREU1  ;  C5CYZ7, PTH_VARPS  ;
DR   A5CVE8, PTH_VESOH  ;  A5F686, PTH_VIBC3  ;  Q9KQ21, PTH_VIBCH  ;
DR   C3LPI9, PTH_VIBCM  ;  B5FBW5, PTH_VIBFM  ;  A7MY77, PTH_VIBHB  ;
DR   Q87RN9, PTH_VIBPA  ;  B7VKG8, PTH_VIBSL  ;  Q8DFF4, PTH_VIBVU  ;
DR   Q7MMZ2, PTH_VIBVY  ;  Q8D2K4, PTH_WIGBR  ;  Q73II8, PTH_WOLPM  ;
DR   Q7M7U8, PTH_WOLSU  ;  Q5GTI9, PTH_WOLTR  ;  C0R594, PTH_WOLWR  ;
DR   Q8PNT8, PTH_XANAC  ;  Q3BX00, PTH_XANC5  ;  Q4URC3, PTH_XANC8  ;
DR   Q8PC61, PTH_XANCP  ;  Q2NZW9, PTH_XANOM  ;  B2SQP2, PTH_XANOP  ;
DR   Q5GWR6, PTH_XANOR  ;  A7IIK5, PTH_XANP2  ;  B2IA78, PTH_XYLF2  ;
DR   Q9PA78, PTH_XYLFA  ;  B0U5Y6, PTH_XYLFM  ;  Q87A24, PTH_XYLFT  ;
DR   P38876, PTH_YEAST  ;  A1JRW1, PTH_YERE8  ;  A7FIG9, PTH_YERP3  ;
DR   Q1C861, PTH_YERPA  ;  Q8ZEY4, PTH_YERPE  ;  Q1CJK8, PTH_YERPN  ;
DR   Q66AY1, PTH_YERPS  ;  Q5NL75, PTH_ZYMMO  ;  Q3SZ85, PTRD1_BOVIN;
DR   Q6GMV3, PTRD1_HUMAN;  D3Z4S3, PTRD1_MOUSE;  Q9J5H2, V029_FOWPN ;
//
ID   3.1.1.30
DE   D-arabinonolactonase.
CA   D-arabinono-1,4-lactone + H(2)O = D-arabinonate.
//
ID   3.1.1.31
DE   6-phosphogluconolactonase.
CA   6-phospho-D-glucono-1,5-lactone + H(2)O = 6-phospho-D-gluconate.
DR   Q9LMX8, 6PGL1_ARATH;  A2XI04, 6PGL1_ORYSI;  Q75IV7, 6PGL1_ORYSJ;
DR   Q8LG70, 6PGL2_ARATH;  A2YNH4, 6PGL2_ORYSI;  Q6Z4H0, 6PGL2_ORYSJ;
DR   Q8LEV7, 6PGL3_ARATH;  A2YXS5, 6PGL3_ORYSI;  Q6Z9C3, 6PGL3_ORYSJ;
DR   Q9FIN1, 6PGL4_ARATH;  A2Z3C4, 6PGL4_ORYSI;  Q69NG5, 6PGL4_ORYSJ;
DR   Q84WW2, 6PGL5_ARATH;  P70715, 6PGL_AGGAC ;  Q7VR81, 6PGL_BLOFL ;
DR   Q492W6, 6PGL_BLOPB ;  O51240, 6PGL_BORBU ;  Q2TBQ8, 6PGL_BOVIN ;
DR   B8D985, 6PGL_BUCA5 ;  P57380, 6PGL_BUCAI ;  Q8K9N9, 6PGL_BUCAP ;
DR   B8D7I7, 6PGL_BUCAT ;  Q89AK3, 6PGL_BUCBP ;  O18229, 6PGL_CAEEL ;
DR   Q9A6N1, 6PGL_CAUCR ;  Q9PKK7, 6PGL_CHLMU ;  Q9Z8U5, 6PGL_CHLPN ;
DR   O84189, 6PGL_CHLTR ;  A8AJ27, 6PGL_CITK8 ;  Q54CJ3, 6PGL_DICDI ;
DR   Q9VZ64, 6PGL_DROME ;  A7ZJE2, 6PGL_ECO24 ;  B7ULP0, 6PGL_ECO27 ;
DR   B7MGM4, 6PGL_ECO45 ;  B7LB75, 6PGL_ECO55 ;  Q8X926, 6PGL_ECO57 ;
DR   B5YRG5, 6PGL_ECO5E ;  B7NNI9, 6PGL_ECO7I ;  B7MPQ2, 6PGL_ECO81 ;
DR   B7M6D0, 6PGL_ECO8A ;  C4ZXT8, 6PGL_ECOBW ;  B1X797, 6PGL_ECODH ;
DR   A7ZY23, 6PGL_ECOHS ;  A1A909, 6PGL_ECOK1 ;  Q0TJT3, 6PGL_ECOL5 ;
DR   Q8FJR2, 6PGL_ECOL6 ;  B1IXL9, 6PGL_ECOLC ;  P52697, 6PGL_ECOLI ;
DR   B7NA10, 6PGL_ECOLU ;  B6I7S1, 6PGL_ECOSE ;  B1LM58, 6PGL_ECOSM ;
DR   Q1REG3, 6PGL_ECOUT ;  A4W8A9, 6PGL_ENT38 ;  A7MIZ2, 6PGL_ENTS8 ;
DR   Q6D7C2, 6PGL_ERWCT ;  B2VBU3, 6PGL_ERWT9 ;  B7LJZ2, 6PGL_ESCF3 ;
DR   Q57039, 6PGL_HAEIN ;  Q9ZKB1, 6PGL_HELPJ ;  O25730, 6PGL_HELPY ;
DR   O95336, 6PGL_HUMAN ;  B5XZA0, 6PGL_KLEP3 ;  A6T6J6, 6PGL_KLEP7 ;
DR   Q9CQ60, 6PGL_MOUSE ;  P63339, 6PGL_MYCBO ;  Q49700, 6PGL_MYCLE ;
DR   P63338, 6PGL_MYCTU ;  P63336, 6PGL_NEIMA ;  P63337, 6PGL_NEIMB ;
DR   P46016, 6PGL_NOSS1 ;  C6DCH7, 6PGL_PECCP ;  Q7N6R1, 6PGL_PHOLL ;
DR   Q9X2N2, 6PGL_PSEAE ;  Q9EV79, 6PGL_PSEPU ;  P85971, 6PGL_RAT   ;
DR   Q989A3, 6PGL_RHILO ;  Q9Z3S1, 6PGL_RHIME ;  B5F063, 6PGL_SALA4 ;
DR   A9MJH1, 6PGL_SALAR ;  Q57RH2, 6PGL_SALCH ;  B5FP52, 6PGL_SALDC ;
DR   B5QX56, 6PGL_SALEP ;  B5R752, 6PGL_SALG2 ;  B4TC39, 6PGL_SALHS ;
DR   B4SZI8, 6PGL_SALNS ;  Q5PG56, 6PGL_SALPA ;  A9MTJ8, 6PGL_SALPB ;
DR   C0PWX3, 6PGL_SALPC ;  B5BC39, 6PGL_SALPK ;  B4TQT0, 6PGL_SALSV ;
DR   Q8Z8A2, 6PGL_SALTI ;  Q8ZQR4, 6PGL_SALTY ;  O74455, 6PGL_SCHPO ;
DR   A8GBC1, 6PGL_SERP5 ;  B2TVG3, 6PGL_SHIB3 ;  Q324C4, 6PGL_SHIBS ;
DR   Q32EZ9, 6PGL_SHIDS ;  Q0T6J2, 6PGL_SHIF8 ;  Q83LP7, 6PGL_SHIFL ;
DR   Q3Z422, 6PGL_SHISS ;  Q2NUK0, 6PGL_SODGM ;  Q9XAB7, 6PGL_STRCO ;
DR   P74618, 6PGL_SYNY3 ;  Q9X0N8, 6PGL_THEMA ;  O83490, 6PGL_TREPA ;
DR   Q9RMP7, 6PGL_XENNA ;  Q9PEG5, 6PGL_XYLFA ;  Q87EG7, 6PGL_XYLFT ;
DR   A1JS71, 6PGL_YERE8 ;  A7FKN1, 6PGL_YERP3 ;  Q1C949, 6PGL_YERPA ;
DR   B2K8S8, 6PGL_YERPB ;  Q8ZGX4, 6PGL_YERPE ;  Q1CFQ1, 6PGL_YERPN ;
DR   A4TNQ8, 6PGL_YERPP ;  Q66D69, 6PGL_YERPS ;  B1JSS6, 6PGL_YERPY ;
DR   O95479, G6PE_HUMAN ;  Q8CFX1, G6PE_MOUSE ;  P56201, G6PE_RABIT ;
DR   B3LSS7, SOL3_YEAS1 ;  B5VK90, SOL3_YEAS6 ;  A6ZT71, SOL3_YEAS7 ;
DR   P38858, SOL3_YEAST ;  P53315, SOL4_YEAST ;
//
ID   3.1.1.32
DE   Phospholipase A(1).
AN   Phospholipase A1.
CA   Phosphatidylcholine + H(2)O = 2-acylglycerophosphocholine +
CA   a carboxylate.
CF   Calcium.
CC   -!- Has a much broader specificity than EC 3.1.1.4.
DR   Q93V61, LCAT3_ARATH;  Q06478, PA11_DOLMA ;  Q6Q252, PA11_POLDO ;
DR   P53357, PA12_DOLMA ;  Q6Q251, PA12_POLDO ;  Q6Q250, PA13_POLDO ;
DR   Q6Q249, PA14_POLDO ;  P0A922, PA1_ECO57  ;  P0A921, PA1_ECOLI  ;
DR   P37446, PA1_KLEPN  ;  Q9K0U7, PA1_NEIMB  ;  Q9U6W0, PA1_POLAN  ;
DR   P83542, PA1_POLGA  ;  A2VBC4, PA1_POLPI  ;  P37447, PA1_PROVU  ;
DR   P0A232, PA1_SALTI  ;  P0A231, PA1_SALTY  ;  P18952, PA1_SERLI  ;
DR   P0A923, PA1_SHIFL  ;  Q68KK0, PA1_SOLIN  ;  P0CH87, PA1_VESCR  ;
DR   Q3ZU95, PA1_VESGE  ;  P51528, PA1_VESMC  ;  P0CH86, PA1_VESSQ  ;
DR   P49369, PA1_VESVU  ;  Q948R1, PLA11_ARATH;  Q9MA46, PLA12_ARATH;
//
ID   3.1.1.33
DE   6-acetylglucose deacetylase.
CA   6-acetyl-D-glucose + H(2)O = D-glucose + acetate.
//
ID   3.1.1.34
DE   Lipoprotein lipase.
AN   Clearing factor lipase.
AN   Diacylglycerol lipase.
AN   Diglyceride lipase.
CA   Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
CC   -!- Hydrolyzes triacylglycerols in chylomicrons and very low-density
CC       lipoproteins (VLDL).
CC   -!- Also hydrolyzes diacylglycerol.
PR   PROSITE; PDOC00110;
DR   P11151, LIPL_BOVIN ;  P11153, LIPL_CAVPO ;  P11602, LIPL_CHICK ;
DR   P55031, LIPL_FELCA ;  P06858, LIPL_HUMAN ;  P11152, LIPL_MOUSE ;
DR   O46647, LIPL_MUSVI ;  P49060, LIPL_PAPAN ;  P49923, LIPL_PIG   ;
DR   Q06000, LIPL_RAT   ;  Q29524, LIPL_SHEEP ;
//
ID   3.1.1.35
DE   Dihydrocoumarin hydrolase.
CA   Dihydrocoumarin + H(2)O = melilotate.
CC   -!- Also hydrolyzes some other benzenoid 1,4-lactones.
//
ID   3.1.1.36
DE   Limonin-D-ring-lactonase.
CA   Limonoate D-ring-lactone + H(2)O = limonoate.
CC   -!- Limonoate is a triterpenoid.
//
ID   3.1.1.37
DE   Steroid-lactonase.
CA   Testololactone + H(2)O = testolate.
//
ID   3.1.1.38
DE   Triacetate-lactonase.
CA   Triacetate lactone + H(2)O = triacetate.
//
ID   3.1.1.39
DE   Actinomycin lactonase.
CA   Actinomycin + H(2)O = actinomycinic monolactone.
//
ID   3.1.1.40
DE   Orsellinate-depside hydrolase.
AN   Lecanorate hydrolase.
CA   Orsellinate depside + H(2)O = 2 orsellinate.
CC   -!- Will only hydrolyze those substrates based on the 2,4-dihydroxy-6-
CC       methylbenzoate structure that also have a free hydroxyl ortho to the
CC       depside linkage.
//
ID   3.1.1.41
DE   Cephalosporin-C deacetylase.
CA   Cephalosporin C + H(2)O = deacetylcephalosporin C + acetate.
CC   -!- Hydrolyzes the acetyl ester bond on the 10-position of the antibiotic
CC       cephalosporin C.
DR   P94388, CAH_BACSU  ;
//
ID   3.1.1.42
DE   Chlorogenate hydrolase.
AN   Chlorogenase.
CA   Chlorogenate + H(2)O = caffeate + quinate.
CC   -!- Also acts, more slowly, on isochlorogenate.
CC   -!- No other substrates are known.
//
ID   3.1.1.43
DE   Alpha-amino-acid esterase.
AN   Alpha-amino-acid ester hydrolase.
CA   An alpha-amino acid ester + H(2)O = an alpha-amino acid + an alcohol.
CC   -!- Also catalyzes alpha-aminoacyl transfer to a number of amine
CC       nucleophiles.
//
ID   3.1.1.44
DE   4-methyloxaloacetate esterase.
CA   Oxaloacetate 4-methyl ester + H(2)O = oxaloacetate + methanol.
//
ID   3.1.1.45
DE   Carboxymethylenebutenolidase.
AN   Dienelactone hydrolase.
AN   Maleylacetate enol-lactonase.
CA   4-carboxymethylenebut-2-en-4-olide + H(2)O = 4-oxohex-2-enedioate.
DR   P0A114, CLCD_PSEPU ;  P0A115, CLCD_PSESB ;  O67988, CLCD_RHOOP ;
DR   O67802, DLHH_AQUAE ;  Q43914, DLHH_AZOBR ;  Q8X8L4, DLHH_ECO57 ;
DR   P56262, DLHH_ECOLI ;  P71505, DLHH_METEA ;  Q8Z3B8, DLHH_SALTI ;
DR   Q9L6M9, DLHH_SALTY ;  P95862, DLHH_SULSO ;  P73163, DLHH_SYNY3 ;
DR   Q07505, DLHH_YEAST ;  Q8ZAL4, DLHH_YERPE ;  P27100, TCBE_PSESQ ;
DR   P27136, TFDE1_CUPPJ;  P94136, TFDE2_CUPPJ;
//
ID   3.1.1.46
DE   Deoxylimonate A-ring-lactonase.
CA   Deoxylimonate + H(2)O = deoxylimononic acid D-ring-lactone.
CC   -!- Opens the A-ring-lactone of the triterpenoid deoxylimonic acid,
CC       leaving the D-ring-lactone intact.
//
ID   3.1.1.47
DE   1-alkyl-2-acetylglycerophosphocholine esterase.
AN   2-acetyl-1-alkylglycerophosphocholine esterase.
AN   LDL-associated phospholipase A(2).
AN   LDL-PLA(2).
AN   PAF 2-acylhydrolase.
AN   PAF acetylhydrolase.
AN   Platelet-activating factor acetylhydrolase.
CA   1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H(2)O = 1-alkyl-
CA   sn-glycero-3-phosphocholine + acetate.
PR   PROSITE; PDOC00110;
DR   Q86U10, LPP60_HUMAN;  A0JNU3, LPP60_MOUSE;  O88202, LPP60_RAT  ;
DR   P68401, PA1B2_BOVIN;  Q5ZMS2, PA1B2_CHICK;  P68402, PA1B2_HUMAN;
DR   Q61206, PA1B2_MOUSE;  Q5R4G2, PA1B2_PONAB;  O35264, PA1B2_RAT  ;
DR   Q29460, PA1B3_BOVIN;  Q15102, PA1B3_HUMAN;  Q61205, PA1B3_MOUSE;
DR   Q5R6X1, PA1B3_PONAB;  O35263, PA1B3_RAT  ;  P79106, PAFA2_BOVIN;
DR   Q99487, PAFA2_HUMAN;  Q8VDG7, PAFA2_MOUSE;  P83006, PAFA2_RAT  ;
DR   Q28017, PAFA_BOVIN ;  Q22943, PAFA_CAEEL ;  Q28262, PAFA_CANFA ;
DR   P70683, PAFA_CAVPO ;  Q90678, PAFA_CHICK ;  Q13093, PAFA_HUMAN ;
DR   Q60963, PAFA_MOUSE ;  Q9URV1, PLG7_SCHPO ;
//
ID   3.1.1.48
DE   Fusarinine-C ornithinesterase.
AN   Ornithine esterase.
CA   N(5)-acyl-L-ornithine ester + H(2)O = N(5)-acyl-L-ornithine + an alcohol.
CC   -!- Hydrolyzes the three ornithine ester bonds in fusarinine C.
CC   -!- Also acts on N(5)-dinitrophenyl-L-ornithine methyl ester.
//
ID   3.1.1.49
DE   Sinapine esterase.
CA   Sinapoylcholine + H(2)O = sinapate + choline.
//
ID   3.1.1.50
DE   Wax-ester hydrolase.
CA   A wax ester + H(2)O = a long-chain alcohol + a long-chain carboxylate.
CC   -!- Also acts on long-chain acylglycerol, but not diacyl- or
CC       triacylglycerols.
//
ID   3.1.1.51
DE   Phorbol-diester hydrolase.
AN   Diacylphorbate 12-hydrolase.
CA   Phorbol 12,13-dibutanoate + H(2)O = phorbol 13-butanoate + butanoate.
CC   -!- Hydrolyzes the 12-ester bond in a variety of 12,13-diacylphorbols
CC       (phorbol is a diterpenoid).
CC   -!- This reaction inactivates tumor promoter 12-O-tetradecanoylphorbol-
CC       13-acetate from croton oil.
//
ID   3.1.1.52
DE   Phosphatidylinositol deacylase.
AN   Phosphatidylinositol phospholipase A2.
CA   1-phosphatidyl-D-myo-inositol + H(2)O = 1-acylglycerophosphoinositol +
CA   a carboxylate.
//
ID   3.1.1.53
DE   Sialate O-acetylesterase.
CA   N-acetyl-O-acetylneuraminate + H(2)O = N-acetylneuraminate + acetate.
CC   -!- Acts on free and glycosidically-bound N-acetyl- or
CC       N-glycoloylneuraminic acid.
CC   -!- Acts mainly on 4-O- and 9-O-acetyl groups.
CC   -!- Also acts on some other O-acetyl esters, both cyclic and acyclic
CC       compounds, which are not sialic acids.
DR   P0C0V9, HEMA_BRV1  ;  P0C0W0, HEMA_BRV2  ;  P59711, HEMA_CVBEN ;
DR   P33468, HEMA_CVBF  ;  Q66165, HEMA_CVBG9 ;  P59710, HEMA_CVBL9 ;
DR   Q9QAR6, HEMA_CVBLS ;  Q8V437, HEMA_CVBLU ;  P31613, HEMA_CVBLY ;
DR   P15776, HEMA_CVBM  ;  Q9QAQ9, HEMA_CVBOK ;  Q9DR81, HEMA_CVBON ;
DR   P59709, HEMA_CVBQ  ;  Q5MQD1, HEMA_CVHN1 ;  Q14EB1, HEMA_CVHN2 ;
DR   Q0ZME8, HEMA_CVHN5 ;  P30215, HEMA_CVHOC ;  P31615, HEMA_CVMA5 ;
DR   O92367, HEMA_CVMDV ;  Q83356, HEMA_CVMJH ;  P31614, HEMA_CVMS  ;
DR   Q8BB26, HEMA_CVP67 ;  Q8JSP9, HEMA_CVPIA ;  O91262, HEMA_CVPV  ;
DR   Q9IKD2, HEMA_CVRSD ;  Q9Q9G3, HEMA_HUTV  ;  P68762, HEMA_INCAA ;
DR   P03465, HEMA_INCCA ;  P07973, HEMA_INCEN ;  P07971, HEMA_INCGL ;
DR   P17003, HEMA_INCHY ;  P07975, HEMA_INCJH ;  P17004, HEMA_INCKY ;
DR   P07970, HEMA_INCMI ;  P17005, HEMA_INCNA ;  Q67387, HEMA_INCNB ;
DR   P07968, HEMA_INCP1 ;  P07967, HEMA_INCP2 ;  P07966, HEMA_INCP3 ;
DR   P07974, HEMA_INCTA ;  P68761, HEMA_INCYA ;  P87691, HEMA_INCYB ;
DR   Q8V3U0, HEMA_ISAVC ;  Q70KP1, HEMA_PTV10 ;  Q9HAT2, SIAE_HUMAN ;
DR   P70665, SIAE_MOUSE ;  Q5RFU0, SIAE_PONAB ;  P82450, SIAE_RAT   ;
//
ID   3.1.1.54
DE   Acetoxybutynylbithiophene deacetylase.
CA   5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene + H(2)O = 5-(4-hydroxybut-1-
CA   ynyl)-2,2'-bithiophene + acetate.
CC   -!- Highly specific.
//
ID   3.1.1.55
DE   Acetylsalicylate deacetylase.
AN   Aspirin esterase.
CA   Acetylsalicylate + H(2)O = salicylate + acetate.
CC   -!- Not identical with EC 3.1.1.1, EC 3.1.1.2, EC 3.1.1.7 or EC 3.1.1.8.
CC   -!- The activity of the liver cytosol enzyme is highest with acetyl
CC       esters of aryl alcohols, and thioesters are also hydrolyzed.
CC   -!- The microsomal enzyme also hydrolyzes some other negatively charged
CC       esters.
CC   -!- Best substrates were esters of salicylate with long-chain alcohols.
//
ID   3.1.1.56
DE   Methylumbelliferyl-acetate deacetylase.
AN   Esterase D.
CA   4-methylumbelliferyl acetate + H(2)O = 4-methylumbelliferone + acetate.
CC   -!- Acts on short-chain acyl esters of 4-methylumbelliferone, but not on
CC       naphthyl, indoxyl or thiocholine esters.
//
ID   3.1.1.57
DE   2-pyrone-4,6-dicarboxylate lactonase.
CA   2-pyrone-4,6-dicarboxylate + H(2)O = 4-carboxy-2-hydroxyhexa-2,4-
CA   dienedioate.
CC   -!- The product isomerizes to 4-oxalmesaconate.
//
ID   3.1.1.58
DE   N-acetylgalactosaminoglycan deacetylase.
CA   N-acetyl-D-galactosaminoglycan + H(2)O = D-galactosaminoglycan + acetate.
//
ID   3.1.1.59
DE   Juvenile-hormone esterase.
AN   JH esterase.
CA   Methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate
CA   + H(2)O = (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-
CA   dienoate + methanol.
CC   -!- Demethylates the insect juvenile hormones, JH(1) and JH(3), but does
CC       not hydrolyze the analogous ethyl or isopropyl esters.
PR   PROSITE; PDOC00112;
DR   P12992, ESTJ_HELVI ;  P19985, ESTJ_MANSE ;  P30809, JHEA_TRINI ;
DR   P30810, JHEB_TRINI ;
//
ID   3.1.1.60
DE   Bis(2-ethylhexyl)phthalate esterase.
CA   Bis(2-ethylhexyl)phthalate + H(2)O = 2-ethylhexyl phthalate +
CA   2-ethylhexan-1-ol.
CC   -!- Also acts on 4-nitrophenyl esters, with optimum acyl chain length
CC       C(6) to C(8).
//
ID   3.1.1.61
DE   Protein-glutamate methylesterase.
AN   CheB methylesterase.
AN   Chemotaxis-specific methylesterase.
AN   Methyl-accepting chemotaxis protein methyl-esterase.
AN   Methylesterase CheB.
AN   PME.
AN   Protein carboxyl methylesterase.
AN   Protein methyl-esterase.
AN   Protein methylesterase.
CA   Protein L-glutamate O(5)-methyl ester + H(2)O = protein L-glutamate +
CA   methanol.
CC   -!- Hydrolyzes the products of EC 2.1.1.77, EC 2.1.1.78, EC 2.1.1.80 and
CC       EC 2.1.1.100.
PR   PROSITE; PDOC50122;
DR   Q1IRH0, CHEB1_ACIBL;  O85128, CHEB1_AGRT5;  Q2INJ8, CHEB1_ANADE;
DR   Q2KV65, CHEB1_BORA1;  Q1BRL2, CHEB1_BURCA;  Q62G12, CHEB1_BURMA;
DR   Q3JY65, CHEB1_BURP1;  Q63PS2, CHEB1_BURPS;  Q394I6, CHEB1_BURS3;
DR   Q2STS8, CHEB1_BURTA;  Q3ADG9, CHEB1_CARHZ;  O87717, CHEB1_CAUCR;
DR   Q7NV40, CHEB1_CHRVO;  Q46V28, CHEB1_CUPPJ;  Q47I43, CHEB1_DECAR;
DR   Q311M8, CHEB1_DESDG;  P62636, CHEB1_DESVH;  Q39WQ9, CHEB1_GEOMG;
DR   P62638, CHEB1_GEOSL;  Q2SPQ1, CHEB1_HAHCH;  P62641, CHEB1_LEPIC;
DR   Q8F6P9, CHEB1_LEPIN;  Q2WAJ8, CHEB1_MAGSA;  Q8TLG9, CHEB1_METAC;
DR   Q2FMT2, CHEB1_METHJ;  Q8Q009, CHEB1_METMA;  Q1D359, CHEB1_MYXXD;
DR   Q6LU34, CHEB1_PHOPR;  Q48ND9, CHEB1_PSE14;  O87125, CHEB1_PSEAE;
DR   Q4KHL8, CHEB1_PSEF5;  Q3KHF6, CHEB1_PSEPF;  Q88EW5, CHEB1_PSEPK;
DR   O52262, CHEB1_PSEPU;  Q884V3, CHEB1_PSESM;  Q4ZYD3, CHEB1_PSEU2;
DR   Q1LH11, CHEB1_RALME;  Q2KCH8, CHEB1_RHIEC;  Q1MLG8, CHEB1_RHIL3;
DR   Q52883, CHEB1_RHIME;  Q221I1, CHEB1_RHOFD;  Q20YL8, CHEB1_RHOPB;
DR   Q2RX18, CHEB1_RHORT;  Q3J653, CHEB1_RHOS4;  Q21IQ9, CHEB1_SACD2;
DR   Q12PJ3, CHEB1_SHEDO;  Q8ECD7, CHEB1_SHEON;  Q0HKN5, CHEB1_SHESM;
DR   Q0HWY6, CHEB1_SHESR;  Q2LR65, CHEB1_SYNAS;  Q0AYL3, CHEB1_SYNWW;
DR   Q9KQD8, CHEB1_VIBCH;  Q87MK5, CHEB1_VIBPA;  Q8DB67, CHEB1_VIBVU;
DR   Q7MIQ5, CHEB1_VIBVY;  Q8PLB4, CHEB1_XANAC;  Q3BUA2, CHEB1_XANC5;
DR   Q4UWU6, CHEB1_XANC8;  Q8P9J7, CHEB1_XANCP;  Q2P5Q6, CHEB1_XANOM;
DR   Q5H2V2, CHEB1_XANOR;  Q1IQS9, CHEB2_ACIBL;  Q2INL1, CHEB2_ANADE;
DR   Q8VL08, CHEB2_AZOBR;  Q2L1D1, CHEB2_BORA1;  Q89T55, CHEB2_BRAJA;
DR   Q1BMF9, CHEB2_BURCA;  Q4V2X4, CHEB2_BURMA;  Q3JJY2, CHEB2_BURP1;
DR   Q63J47, CHEB2_BURPS;  Q393F2, CHEB2_BURS3;  Q2T8Y6, CHEB2_BURTA;
DR   Q3ADA6, CHEB2_CARHZ;  Q9AAK0, CHEB2_CAUCR;  Q7NZB3, CHEB2_CHRVO;
DR   Q46PH7, CHEB2_CUPPJ;  Q47GX7, CHEB2_DECAR;  Q30ZJ5, CHEB2_DESDG;
DR   P62637, CHEB2_DESVH;  Q39T95, CHEB2_GEOMG;  P62639, CHEB2_GEOSL;
DR   Q2SFY4, CHEB2_HAHCH;  P62642, CHEB2_LEPIC;  Q8F5D8, CHEB2_LEPIN;
DR   Q2W5V5, CHEB2_MAGSA;  Q8TUQ0, CHEB2_METAC;  Q2FQU2, CHEB2_METHJ;
DR   Q8PX96, CHEB2_METMA;  Q1D225, CHEB2_MYXXD;  Q6LTM2, CHEB2_PHOPR;
DR   Q48GG6, CHEB2_PSE14;  Q9I6V9, CHEB2_PSEAE;  Q4KG36, CHEB2_PSEF5;
DR   Q3KFZ6, CHEB2_PSEPF;  Q888V8, CHEB2_PSESM;  Q4ZWW3, CHEB2_PSEU2;
DR   Q1LG90, CHEB2_RALME;  Q1MC14, CHEB2_RHIL3;  P72253, CHEB2_RHOCS;
DR   Q21ZZ9, CHEB2_RHOFD;  P62644, CHEB2_RHOPA;  Q20XK3, CHEB2_RHOPB;
DR   Q2RUI8, CHEB2_RHORT;  Q3J1W3, CHEB2_RHOS4;  Q8KLS5, CHEB2_RHOSH;
DR   Q21G20, CHEB2_SACD2;  Q12IZ9, CHEB2_SHEDO;  Q8EF61, CHEB2_SHEON;
DR   Q0HIF6, CHEB2_SHESM;  Q0HVI0, CHEB2_SHESR;  Q2LSL3, CHEB2_SYNAS;
DR   Q0AXB7, CHEB2_SYNWW;  Q8D4X6, CHEB2_VIBVU;  Q7MBQ5, CHEB2_VIBVY;
DR   Q8PIM5, CHEB2_XANAC;  Q3BR57, CHEB2_XANC5;  Q4UU97, CHEB2_XANC8;
DR   Q8P7A6, CHEB2_XANCP;  Q2P1V8, CHEB2_XANOM;  Q5GYV8, CHEB2_XANOR;
DR   Q2IQ87, CHEB3_ANADE;  Q89SQ1, CHEB3_BRAJA;  Q1BLQ3, CHEB3_BURCA;
DR   Q39KQ1, CHEB3_BURS3;  Q2T8Y5, CHEB3_BURTA;  Q7NSI8, CHEB3_CHRVO;
DR   Q39SY1, CHEB3_GEOMG;  P62640, CHEB3_GEOSL;  Q2SFK0, CHEB3_HAHCH;
DR   P62643, CHEB3_LEPIC;  Q8F3H4, CHEB3_LEPIN;  Q2W2W9, CHEB3_MAGSA;
DR   Q1CZL0, CHEB3_MYXXD;  Q48F23, CHEB3_PSE14;  Q9HXT8, CHEB3_PSEAE;
DR   Q88MS5, CHEB3_PSEPK;  Q886S8, CHEB3_PSESM;  Q4ZQV7, CHEB3_PSEU2;
DR   Q92YM4, CHEB3_RHIME;  P62645, CHEB3_RHOPA;  Q20XE6, CHEB3_RHOPB;
DR   Q2RRX2, CHEB3_RHORT;  O33558, CHEB3_RHOSH;  Q8EEQ0, CHEB3_SHEON;
DR   Q0AWZ8, CHEB3_SYNWW;  Q9KS59, CHEB3_VIBCH;  Q2IQR9, CHEB4_ANADE;
DR   Q2T7Z3, CHEB4_BURTA;  Q39S45, CHEB4_GEOMG;  Q2SBX9, CHEB4_HAHCH;
DR   Q1CX06, CHEB4_MYXXD;  Q2IQS6, CHEB5_ANADE;  Q39QJ2, CHEB5_GEOMG;
DR   Q1CWZ9, CHEB5_MYXXD;  Q2ILG8, CHEB6_ANADE;  Q0A9Z5, CHEB_ALHEH ;
DR   O29221, CHEB_ARCFU ;  Q9KA55, CHEB_BACHD ;  Q65JK6, CHEB_BACLD ;
DR   Q05522, CHEB_BACSU ;  P62635, CHEB_BDEBA ;  Q7WJE7, CHEB_BORBR ;
DR   Q45047, CHEB_BORBU ;  Q7WAA4, CHEB_BORPA ;  Q7VZ94, CHEB_BORPE ;
DR   Q13SY2, CHEB_BURXL ;  Q1QVY7, CHEB_CHRSD ;  Q97GZ3, CHEB_CLOAB ;
DR   Q485K0, CHEB_COLP3 ;  Q24T61, CHEB_DESHY ;  Q6AJV3, CHEB_DESPS ;
DR   Q8XCF9, CHEB_ECO57 ;  Q0TGV0, CHEB_ECOL5 ;  Q8FGP5, CHEB_ECOL6 ;
DR   P07330, CHEB_ECOLI ;  Q1RAQ1, CHEB_ECOUT ;  Q9FAD8, CHEB_ENTCL ;
DR   Q6D6I7, CHEB_ERWCT ;  Q5L0L0, CHEB_GEOKA ;  Q5FQQ0, CHEB_GLUOX ;
DR   Q5V0B3, CHEB_HALMA ;  Q9HQW6, CHEB_HALSA ;  Q5QZQ3, CHEB_IDILO ;
DR   Q1MP86, CHEB_LAWIP ;  Q0ARY3, CHEB_MARMM ;  Q46DT6, CHEB_METBF ;
DR   Q12YX1, CHEB_METBU ;  Q1GZZ0, CHEB_METFK ;  P62647, CHEB_METMP ;
DR   Q2RKH8, CHEB_MOOTA ;  Q3IRR4, CHEB_NATPD ;  Q820K0, CHEB_NITEU ;
DR   Q1QI44, CHEB_NITHX ;  Q2YC79, CHEB_NITMU ;  Q3SVA1, CHEB_NITWN ;
DR   A1SMR4, CHEB_NOCSJ ;  B2J4Q8, CHEB_NOSP7 ;  Q8EQW0, CHEB_OCEIH ;
DR   Q3A5A8, CHEB_PELCD ;  Q7N5T1, CHEB_PHOLL ;  Q15RF6, CHEB_PSEA6 ;
DR   Q3IDZ3, CHEB_PSEHT ;  Q9UYF3, CHEB_PYRAB ;  O58192, CHEB_PYRHO ;
DR   Q5JF95, CHEB_PYRKO ;  Q8XQ83, CHEB_RALSO ;  Q98PD1, CHEB_RHILO ;
DR   Q2IT50, CHEB_RHOP2 ;  Q132U2, CHEB_RHOPS ;  Q167K9, CHEB_ROSDO ;
DR   Q57N81, CHEB_SALCH ;  Q5PMY3, CHEB_SALPA ;  Q2RZD2, CHEB_SALRD ;
DR   Q8Z5V2, CHEB_SALTI ;  P04042, CHEB_SALTY ;  Q085K9, CHEB_SHEFN ;
DR   Q322K2, CHEB_SHIBS ;  Q83R52, CHEB_SHIFL ;  Q3Z2R1, CHEB_SHISS ;
DR   Q30RX5, CHEB_SULDN ;  Q67P67, CHEB_SYMTH ;  Q9WYN9, CHEB_THEMA ;
DR   Q8RAZ3, CHEB_THETN ;  Q31HL9, CHEB_THICR ;  Q3SIG0, CHEB_THIDA ;
DR   P62646, CHEB_TREDE ;  O83639, CHEB_TREPA ;  Q10WZ6, CHEB_TRIEI ;
DR   Q5E3S1, CHEB_VIBF1 ;  Q1C6W3, CHEB_YERPA ;  Q8ZFM0, CHEB_YERPE ;
DR   Q1CI99, CHEB_YERPN ;  Q669T5, CHEB_YERPS ;  Q9X005, CHED_THEMA ;
DR   P31758, FRZG_MYXXA ;  O51376, Y415_BORBU ;
//
ID   3.1.1.62
DE   Transferred entry: 3.5.1.47.
//
ID   3.1.1.63
DE   11-cis-retinyl-palmitate hydrolase.
CA   11-cis-retinyl palmitate + H(2)O = 11-cis-retinol + palmitate.
CC   -!- Activated by bile salts.
//
ID   3.1.1.64
DE   All-trans-retinyl-palmitate hydrolase.
CA   All-trans-retinyl palmitate + H(2)O = all-trans-retinol + palmitate.
CC   -!- Requires detergents for activity.
DR   Q9YI25, RPE65_AMBTI;  Q28175, RPE65_BOVIN;  Q9TVB8, RPE65_CANFA;
DR   Q9YGX2, RPE65_CHICK;  Q9XT71, RPE65_CHLAE;  Q8AXN9, RPE65_CYNPY;
DR   Q16518, RPE65_HUMAN;  Q91ZQ5, RPE65_MOUSE;  O70276, RPE65_RAT  ;
//
ID   3.1.1.65
DE   L-rhamnono-1,4-lactonase.
CA   L-rhamnono-1,4-lactone + H(2)O = L-rhamnonate.
//
ID   3.1.1.66
DE   5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase.
CA   5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene + H(2)O = 5-(3-hydroxy-4-
CA   acetoxybut-1-ynyl)-2,2'-bithiophene + acetate.
CC   -!- A highly specific enzyme from Tagetes patula.
//
ID   3.1.1.67
DE   Fatty-acyl-ethyl-ester synthase.
AN   FAEE synthase.
AN   FAEES.
CA   A long-chain-fatty-acyl ethyl ester + H(2)O = a long-chain-fatty acid +
CA   ethanol.
CC   -!- In the reverse reaction, forms ethyl esters from fatty acids and
CC       ethanol in the absence of coenzyme A or ATP.
CC   -!- Best substrates are unsaturated octadecanoic acids; palmitate,
CC       stearate and arachidonate also act, more slowly.
DR   Q8VCT4, CES3_MOUSE ;  P16303, CES3_RAT   ;
//
ID   3.1.1.68
DE   Xylono-1,4-lactonase.
CA   D-xylono-1,4-lactone + H(2)O = D-xylonate.
//
ID   3.1.1.69
DE   Transferred entry: 3.5.1.89.
//
ID   3.1.1.70
DE   Cetraxate benzylesterase.
CA   Cetraxate benzyl ester + H(2)O = cetraxate + benzyl alcohol.
CC   -!- Acts on a number of benzyl esters of substituted phenyl propanoates,
CC       and on the benzyl esters of phenylalanine and tyrosine.
//
ID   3.1.1.71
DE   Acetylalkylglycerol acetylhydrolase.
AN   Alkylacetylglycerol acetylhydrolase.
CA   2-acetyl-1-alkyl-sn-glycerol + H(2)O = 1-alkyl-sn-glycerol + acetate.
CC   -!- Hydrolysis of the acetyl group from the 1-alkyl-2-acetyl and 1-alkyl-
CC       3-acetyl substrates occurs at apparently identical rates.
CC   -!- Differs from EC 3.1.1.34 since 1,2-diacetyl-sn-glycerols are not
CC       substrates.
CC   -!- It also differs from EC 3.1.1.47.
//
ID   3.1.1.72
DE   Acetylxylan esterase.
CA   Deacetylation of xylans and xylo-oligosaccharides.
CC   -!- Catalyzes the hydrolysis of acetyl groups from polymeric xylan,
CC       acetylated xylose, acetylated glucose, alpha-napthyl acetate,
CC       p-nitrophenyl acetate but not from triacetylglycerol.
CC   -!- Does not act on acetylated mannan or pectin.
DR   Q92194, AXE1_ASPAW ;  A1CSZ8, AXE1_ASPCL ;  Q96W96, AXE1_ASPFI ;
DR   A9JPE6, AXE1_ASPFL ;  B8NBI2, AXE1_ASPFN ;  Q4WBW4, AXE1_ASPFU ;
DR   A2QZI3, AXE1_ASPNC ;  Q75P26, AXE1_ASPOR ;  Q0C8Z1, AXE1_ASPTN ;
DR   Q5B037, AXE1_EMENI ;  A1DBP9, AXE1_NEOFI ;  Q8NJP6, AXE1_PENPU ;
DR   Q99034, AXE1_TRIRE ;  O59893, AXE2_PENPU ;  P94388, CAH_BACSU  ;
//
ID   3.1.1.73
DE   Feruloyl esterase.
AN   Cinnamoyl ester hydrolase.
AN   Ferulic acid esterase.
AN   Hydroxycinnamoyl esterase.
CA   Feruloyl-polysaccharide + H(2)O = ferulate + polysaccharide.
CC   -!- Catalyzes the hydrolysis of the 4-hydroxy-3-methoxycinnamoyl
CC       (feruloyl) group from an esterified sugar, which is usually arabinose
CC       in 'natural' substrates.
CC   -!- p-nitrophenol acetate and methyl ferulate are poorer substrates.
CC   -!- All microbial ferulate esterases are secreted into the culture
CC       medium.
CC   -!- They are sometimes called hemicellulase accessory enzymes, since they
CC       help xylanases and pectinases to break down plant cell wall
CC       hemicellulose.
DR   Q9P979, FAEA_ASPAW ;  B8NIB8, FAEA_ASPFN ;  A2QSY5, FAEA_ASPNC ;
DR   O42807, FAEA_ASPNG ;  Q2UNW5, FAEA_ASPOR ;  Q0CBM7, FAEA_ASPTN ;
DR   O42815, FAEA_ASPTU ;  B0YDW9, FAEB1_ASPFC;  B8NPA4, FAEB1_ASPFN;
DR   Q4W8Z9, FAEB1_ASPFU;  Q2UP89, FAEB1_ASPOR;  Q0CVS2, FAEB1_ASPTN;
DR   A1DKV3, FAEB1_NEOFI;  B0Y7U1, FAEB2_ASPFC;  B8NPT0, FAEB2_ASPFN;
DR   Q4WMR0, FAEB2_ASPFU;  Q2UMX6, FAEB2_ASPOR;  Q0CI21, FAEB2_ASPTN;
DR   A1DMV3, FAEB2_NEOFI;  A1CTK4, FAEB_ASPCL ;  A2R0Z6, FAEB_ASPNC ;
DR   Q8WZI8, FAEB_ASPNG ;  Q5BCF8, FAEB_EMENI ;  Q9HGR3, FAEB_NEUCR ;
DR   Q9HE18, FAEB_PENFN ;  Q9Y871, FAEB_PIREQ ;  A1C9D4, FAEC1_ASPCL;
DR   A1CC33, FAEC2_ASPCL;  B0XU32, FAEC_ASPFC ;  B8N7Z6, FAEC_ASPFN ;
DR   A4D9B6, FAEC_ASPFU ;  A2QYU7, FAEC_ASPNC ;  Q2UI81, FAEC_ASPOR ;
DR   Q0CDX2, FAEC_ASPTN ;  Q5B2G3, FAEC_EMENI ;  A1DI08, FAEC_NEOFI ;
//
ID   3.1.1.74
DE   Cutinase.
AN   Cutin hydrolase.
CA   Cutin + H(2)O = cutin monomers.
CC   -!- Cutin, a polymeric structural component of plant cuticles, is an
CC       hydroxy fatty acid polymer, usually C(16) or C(18) and that contains
CC       one to three hydroxyl groups.
CC   -!- The enzyme from several fungal sources also hydrolyzes the
CC       p-nitrophenyl esters of hexadecanoic acid.
CC   -!- It is however inactive toward several esters that are substrates for
CC       non-specific esterases.
PR   PROSITE; PDOC00140;
DR   P63880, CUT1_MYCBO ;  P63879, CUT1_MYCTU ;  P63882, CUT2_MYCBO ;
DR   P63881, CUT2_MYCTU ;  P0A537, CUT3_MYCBO ;  P0A536, CUT3_MYCTU ;
DR   A1CSZ4, CUTI1_ASPCL;  B0XRY3, CUTI1_ASPFC;  B8MVS3, CUTI1_ASPFN;
DR   Q4X1N0, CUTI1_ASPFU;  A2R2W3, CUTI1_ASPNC;  P52956, CUTI1_ASPOR;
DR   Q0CD01, CUTI1_ASPTN;  P11373, CUTI1_COLGL;  P86010, CUTI1_COLKA;
DR   Q5B2C1, CUTI1_EMENI;  P00590, CUTI1_FUSSO;  A1DGN0, CUTI1_NEOFI;
DR   B6HLS9, CUTI1_PENCW;  B0Y537, CUTI2_ASPFC;  B8NBB2, CUTI2_ASPFN;
DR   Q4WQV2, CUTI2_ASPFU;  A5ABE6, CUTI2_ASPNC;  Q2TZY7, CUTI2_ASPOR;
DR   Q0CES4, CUTI2_ASPTN;  P86011, CUTI2_COLGL;  P86012, CUTI2_COLKA;
DR   Q5AVY9, CUTI2_EMENI;  Q96UT0, CUTI2_FUSSO;  A1CVT3, CUTI2_NEOFI;
DR   B6H2E9, CUTI2_PENCW;  A1C9G0, CUTI3_ASPCL;  B0YEP5, CUTI3_ASPFC;
DR   B8NCM8, CUTI3_ASPFN;  Q4W9Z4, CUTI3_ASPFU;  Q2U199, CUTI3_ASPOR;
DR   Q0CNE3, CUTI3_ASPTN;  Q5AX00, CUTI3_EMENI;  Q96US9, CUTI3_FUSSO;
DR   A1D9W1, CUTI3_NEOFI;  Q0CW01, CUTI4_ASPTN;  Q0CRP4, CUTI5_ASPTN;
DR   P41744, CUTI_ALTBR ;  P29292, CUTI_ASCRA ;  Q00298, CUTI_BOTFU ;
DR   P10951, CUTI_COLCA ;  Q8X1P1, CUTI_ERYGR ;  Q99174, CUTI_FUSSC ;
DR   P30272, CUTI_MAGO7 ;  Q8TGB8, CUTI_MONFR ;  P41754, CUTI_PHYCP ;
DR   Q9Y7G8, CUTI_PYRBR ;
//
ID   3.1.1.75
DE   Poly(3-hydroxybutyrate) depolymerase.
AN   PHB depolymerase.
AN   Poly((R)-hydroxyalkanoic acid) depolymerase.
AN   Poly(3HB) depolymerase.
AN   Poly(HA(SCL)) depolymerase.
AN   Poly(HA) depolymerase.
CA   ((R)-3-hydroxybutanoate)(n) + H(2)O = ((R)-3-hydroxybutanoate)(n-1 to 5)
CA   + ((R)-3-hydroxybutanoate)(1-5).
CC   -!- Reaction also occurs with esters of other short-chain-length (C(1)-
CC       C(5)) hydroxyalkanoic acids (HA).
CC   -!- There are two types of polymers: native (intracellular) granules are
CC       amorphous and have an intact surface layer; denatured (extracellular)
CC       granules either have no surface layer or a damaged surface layer and
CC       are partially crystalline.
DR   P12625, PHB_BURPI  ;
//
ID   3.1.1.76
DE   Poly(3-hydroxyoctanoate) depolymerase.
AN   PHA depolymerase.
AN   PHO depolymerase.
AN   Poly((R)-3-hydroxyoctanoate) hydrolase.
AN   Poly((R)-hydroxyalkanoic acid) depolymerase.
AN   Poly(3HO) depolymerase.
AN   Poly(HA(MCL)) depolymerase.
AN   Poly(HA) depolymerase.
CA   Hydrolyzes the polyester poly(oxycarbonyl((R)-2-pentylethylene)) to
CA   oligomers.
CC   -!- The main product after prolonged incubation is the dimer.
CC   -!- Besides hydrolyzing polymers of 3-hydroxyoctanoic acid, the enzyme
CC       also hydrolyzes other polymers derived from medium-chain-length
CC       (C(6)-C(12)) hydroxyalkanoic acids and copolymers of mixtures of
CC       these.
CC   -!- It also hydrolyzes p-nitrophenyl esters of fatty acids.
CC   -!- Polymers of short-chain-length hydroxyalkanoic acids such as
CC       poly((R)-3-hydroxybutanoic acid) and poly((R)-3-hydroxypentanoic
CC       acid) are not hydrolyzed.
DR   Q51718, PHAZ_PSEFL ;
//
ID   3.1.1.77
DE   Acyloxyacyl hydrolase.
CA   3-(acyloxy)acyl group of bacterial toxin = 3-hydroxyacyl group of
CA   bacterial toxin + a fatty acid.
CC   -!- The substrate is lipid A on the reducing end of the toxic
CC       lipopolysaccharide (LPS) of Salmonella typhimurium and related
CC       organisms.
CC   -!- It consists of diglucosamine, beta-D-GlcN-(1->6)-D-GlcN, attached by
CC       glycosylation on O-6 of its non-reducing residue, phosphorylated on
CC       O-4 of this residue and on O-1 of its potentially reducing residue.
CC   -!- Both residues carry 3-(acyloxy)acyl groups on N-2 and O-3.
CC   -!- The enzyme from human leukocytes detoxifies the lipid by hydrolyzing
CC       the secondary acyl groups from O-3 of the 3-hydroxyacyl groups on the
CC       disaccharide (LPS).
CC   -!- It also possesses a wide range of phospholipase and acyltransferase
CC       activities (e.g. EC 3.1.1.4, EC 3.1.1.5, EC 3.1.1.32 and
CC       EC 3.1.1.52), hydrolyzing diacylglycerol and phosphatidyl compounds,
CC       but not triacylglycerols.
CC   -!- It has a preference for saturated C(12)-C(16) acyl groups.
DR   P28039, AOAH_HUMAN ;  O35298, AOAH_MOUSE ;  O18823, AOAH_RABIT ;
//
ID   3.1.1.78
DE   Polyneuridine-aldehyde esterase.
AN   PNAE.
AN   Polyneuridine aldehyde esterase.
CA   Polyneuridine aldehyde + H(2)O = 16-epivellosimine + CO(2) + methanol.
CC   -!- Following hydrolysis of this indole alkaloid ester, the carboxylic
CC       acid decarboxylates spontaneously giving the sarpagan skeleton.
CC   -!- Also acts on akuammidine aldehyde (the 16-epimer of polyneuridine
CC       aldehyde).
DR   Q9SE93, PNAE_RAUSE ;
//
ID   3.1.1.79
DE   Hormone-sensitive lipase.
AN   HSL.
CA   (1) Diacylglycerol + H(2)O = monoacylglycerol + a carboxylate.
CA   (2) Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
CA   (3) Monoacylglycerol + H(2)O = glycerol + a carboxylate.
CC   -!- This enzyme is a serine hydrolase.
CC   -!- Compared with other lipases, hormone-sensitive lipase has a uniquely
CC       broad substrate specificity.
CC   -!- It hydrolyzes all acylglycerols (triacylglycerol, diacylglycerol and
CC       monoacylglycerol) as well as cholesteryl esters, steroid fatty acid
CC       esters, retinyl esters and p-nitrophenyl esters.
CC   -!- It exhibits a preference for the 1- or 3-ester bond of its
CC       acylglycerol substrate compared with the 2-ester bond.
CC   -!- The enzyme shows little preference for the fatty acids in the
CC       triacylglycerol, although there is some increase in activity with
CC       decreasing chain length.
CC   -!- The enzyme activity is increased in response to hormones that elevate
CC       intracellular levels of cAMP.
PR   PROSITE; PDOC00903;
DR   P16386, LIPS_BOVIN ;  Q05469, LIPS_HUMAN ;  P54310, LIPS_MOUSE ;
DR   Q68J42, LIPS_PIG   ;  P15304, LIPS_RAT   ;  Q9R101, LIPS_SPETR ;
//
ID   3.1.1.80
DE   Acetylajmaline esterase.
AN   2-beta-(R)-17-O-acetylajmalan:acetylesterase.
AN   AAE.
AN   Acetylajmalan esterase.
CA   (1) 17-O-acetylajmaline + H(2)O = ajmaline + acetate.
CA   (2) 17-O-acetylnorajmaline + H(2)O = norajmaline + acetate.
CC   -!- Responsible for the last stages in the biosynthesis of the indole
CC       alkaloid ajmaline.
CC   -!- Highly specific for the substrates 17-O-acetylajmaline and 17-O-
CC       acetylnorajmaline as the structurally related acetylated alkaloids
CC       vinorine, vomilenine, 1,2-dihydrovomilenine and 1,2-
CC       dihydroraucaffricine cannot act as substrates.
DR   Q3MKY2, AAE_RAUSE  ;  P86830, AAE_RAUVE  ;
//
ID   3.1.1.81
DE   Quorum-quenching N-acyl-homoserine lactonase.
AN   Acyl homoserine degrading enzyme.
AN   Acyl-homoserine-lactone acylase.
AN   AHL lactonase.
AN   AHL-degrading enzyme.
AN   AHL-inactivating enzyme.
AN   AHLase.
AN   N-acyl homoserine lactonase.
AN   N-acyl homoserine lactone hydrolase.
AN   N-acyl-homoserine lactone lactonase.
AN   N-acyl-L-homoserine lactone hydrolase.
AN   Quorum-quenching lactonase.
AN   Quorum-quenching N-acyl homoserine lactone hydrolase.
CA   An N-acyl-L-homoserine lactone + H(2)O = an N-acyl-L-homoserine.
CC   -!- Acyl-homoserine lactones (AHLs) are produced by a number of bacterial
CC       species and are used by them to regulate the expression of virulence
CC       genes in a process known as quorum-sensing.
CC   -!- Each bacterial cell has a basal level of AHL and, once the population
CC       density reaches a critical level, it triggers AHL-signaling which,
CC       in turn, initiates the expression of particular virulence genes.
CC   -!- Plants or animals capable of degrading AHLs would have a therapeutic
CC       advantage in avoiding bacterial infection as they could prevent AHL-
CC       signaling and the expression of virulence genes in quorum-sensing
CC       bacteria.
CC   -!- N-(3-oxohexanoyl)-L-homoserine lactone, N-(3-oxododecanoyl)-L-
CC       homoserine lactone, N-butanoyl-L-homoserine lactone and
CC       N-(3-oxooctanoyl)-L-homoserine lactone can act as substrates.
DR   P0CJ63, AHLLA_BACTK;  B9JPK6, AHLLB_AGRRK;  A9CKY2, AHLLB_AGRT5;
DR   Q7D3U0, AHLLM_AGRT5;  A8IQD2, AHLLM_AZOC5;  Q1M813, AHLLM_RHIL3;
DR   Q8VPD5, AHLLM_RHIRD;  Q7X3T2, AHLL_ARTSP ;  Q08GP4, AHLL_BACCE ;
DR   Q9L8R8, AHLL_BACSP ;  Q7B8C3, AHLL_BACT3 ;  Q7B8C5, AHLL_BACTA ;
DR   A3FJ64, AHLL_BACTU ;  C6L862, AHLL_MICTS ;  P27169, PON1_HUMAN ;
DR   P52430, PON1_MOUSE ;  P27170, PON1_RABIT ;  P55159, PON1_RAT   ;
DR   Q58DS7, PON2_BOVIN ;  P54832, PON2_CANFA ;  Q15165, PON2_HUMAN ;
DR   Q62086, PON2_MOUSE ;  Q6AXM8, PON2_RAT   ;  Q15166, PON3_HUMAN ;
DR   Q62087, PON3_MOUSE ;  Q9BGN0, PON3_RABIT ;  Q68FP2, PON3_RAT   ;
//
ID   3.1.1.82
DE   Pheophorbidase.
AN   Phedase.
AN   PPD.
CA   Pheophorbide a + H(2)O = pyropheophorbide a + methanol + CO(2).
CC   -!- Forms part of the chlorophyll degradation pathway, and is found in
CC       higher plants and in algae.
CC   -!- In higher plants it participates in de-greening processes such as
CC       fruit ripening, leaf senescence, and flowering.
CC   -!- Exists in two forms: type 1 is induced by senescence whereas type 2
CC       is constitutively expressed.
CC   -!- Highly specific for pheophorbide as substrate (with a preference for
CC       pheophorbide a over pheophorbide b) as other chlorophyll derivatives
CC       such as protochlorophyllide a, pheophytin a and c, chlorophyll a and
CC       b, and chlorophyllide a cannot act as substrates.
CC   -!- Another enzyme, called pheophorbide demethoxycarbonylase (PDC),
CC       produces pyropheophorbide a from pheophorbide a without forming an
CC       intermediate although the precise reaction is not yet known.
PR   PROSITE; PDOC00110;
DR   O23512, PPD_ARATH  ;  Q2V0W1, PPD_RAPSA  ;
//
ID   3.1.1.83
DE   Monoterpene epsilon-lactone hydrolase.
AN   MLH.
CA   Isoprop(en)ylmethyloxepan-2-one + H(2)O =
CA   6-hydroxyisoprop(en)ylmethylhexanoate.
CC   -!- Catalyzes the ring opening of epsilon-lactones which are formed
CC       during degradation of dihydrocarveol by the Gram-positive bacterium
CC       Rhodococcus erythropolis DCL14.
CC   -!- Also acts on ethyl caproate, indicating that it is an esterase with a
CC       preference for lactones (internal cyclic esters).
CC   -!- Not stereoselective.
PR   PROSITE; PDOC00903;
DR   Q9EX73, MLHB_RHOER ;
//
ID   3.1.1.84
DE   Cocaine esterase.
AN   Human carboxylesterase 2.
CA   Cocaine + H(2)O = ecgonine methyl ester + benzoate.
CC   -!- Rhodococcus sp. strain MB1 and Pseudomonas maltophilia strain MB11L
CC       can utilize cocaine as sole source of carbon and energy.
PR   PROSITE; PDOC00112;
DR   O00748, EST2_HUMAN ;
//
ID   3.1.1.85
DE   Pimelyl-[acyl-carrier protein] methyl ester esterase.
CA   Pimelyl-[acyl-carrier protein] methyl ester + H(2)O = pimelyl-[acyl-
CA   carrier protein] + methanol.
CC   -!- Involved in biotin biosynthesis in Gram-negative bacteria.
CC   -!- The enzyme exhibits carboxylesterase activity, particularly toward
CC       substrates with short acyl chains.
CC   -!- Even though the enzyme can interact with coenzyme A thioesters,
CC       the in vivo role of the enzyme is to hydrolyze the methyl ester of
CC       pimelyl-[acyl carrier protein], terminating the part of the biotin
CC       biosynthesis pathway that is catalyzed by the fatty acid elongation
CC       enzymes.
DR   A0KF11, BIOH_AERHH ;  A4ST17, BIOH_AERS4 ;  B6EPQ0, BIOH_ALISL ;
DR   Q5NZF6, BIOH_AROAE ;  Q89A54, BIOH_BUCBP ;  Q7NPW5, BIOH_CHRVO ;
DR   A8AQW5, BIOH_CITK8 ;  A7ZSU1, BIOH_ECO24 ;  B7UKB7, BIOH_ECO27 ;
DR   B7MDN8, BIOH_ECO45 ;  B7L4T9, BIOH_ECO55 ;  Q8X716, BIOH_ECO57 ;
DR   B5YTW3, BIOH_ECO5E ;  B7NMH7, BIOH_ECO7I ;  B7N145, BIOH_ECO81 ;
DR   B7M1W8, BIOH_ECO8A ;  C4ZUR7, BIOH_ECOBW ;  B1X758, BIOH_ECODH ;
DR   A8A5M0, BIOH_ECOHS ;  A1AGT6, BIOH_ECOK1 ;  Q0TC55, BIOH_ECOL5 ;
DR   Q8FCT4, BIOH_ECOL6 ;  B1IP53, BIOH_ECOLC ;  P13001, BIOH_ECOLI ;
DR   B7NE17, BIOH_ECOLU ;  B6I2X6, BIOH_ECOSE ;  B1LHL2, BIOH_ECOSM ;
DR   Q1R5M2, BIOH_ECOUT ;  C5BGT3, BIOH_EDWI9 ;  A7MGD2, BIOH_ENTS8 ;
DR   Q6CZL9, BIOH_ERWCT ;  B7LSB5, BIOH_ESCF3 ;  C4K407, BIOH_HAMD5 ;
DR   Q5QZC0, BIOH_IDILO ;  B5XTS4, BIOH_KLEP3 ;  A6TF35, BIOH_KLEP7 ;
DR   Q5X590, BIOH_LEGPA ;  A5IBW4, BIOH_LEGPC ;  Q5ZVG6, BIOH_LEGPH ;
DR   Q5WW99, BIOH_LEGPL ;  Q609V0, BIOH_METCA ;  Q5F641, BIOH_NEIG1 ;
DR   Q9JSN0, BIOH_NEIMA ;  Q9K197, BIOH_NEIMB ;  A1KRU9, BIOH_NEIMF ;
DR   E6MWF8, BIOH_NEIMH ;  Q82SL8, BIOH_NITEU ;  Q2Y9Y7, BIOH_NITMU ;
DR   C6DGH6, BIOH_PECCP ;  Q7N9V7, BIOH_PHOLL ;  Q6LVQ7, BIOH_PHOPR ;
DR   B4EZM6, BIOH_PROMH ;  Q15N09, BIOH_PSEA6 ;  B5F8M6, BIOH_SALA4 ;
DR   A9MMB5, BIOH_SALAR ;  Q57IW5, BIOH_SALCH ;  B5FJT1, BIOH_SALDC ;
DR   B5R369, BIOH_SALEP ;  B5R7K5, BIOH_SALG2 ;  B4TKT6, BIOH_SALHS ;
DR   B4SVL3, BIOH_SALNS ;  Q5PLY8, BIOH_SALPA ;  C0Q0I5, BIOH_SALPC ;
DR   B5BHG7, BIOH_SALPK ;  Q8Z221, BIOH_SALTI ;  Q8ZLI9, BIOH_SALTY ;
DR   Q8GHL1, BIOH_SERMA ;  A8GKT5, BIOH_SERP5 ;  Q8E8N6, BIOH_SHEON ;
DR   Q0HPU6, BIOH_SHESR ;  B1KM44, BIOH_SHEWM ;  B2U3M2, BIOH_SHIB3 ;
DR   Q31VM0, BIOH_SHIBS ;  Q32AM6, BIOH_SHIDS ;  Q83PW0, BIOH_SHIFL ;
DR   Q3YWL3, BIOH_SHISS ;  Q2NQH6, BIOH_SODGM ;  B4SM83, BIOH_STRM5 ;
DR   B2FLM6, BIOH_STRMK ;  C4LA13, BIOH_TOLAT ;  Q9KNL4, BIOH_VIBCH ;
DR   Q5E8N3, BIOH_VIBF1 ;  B5FFE9, BIOH_VIBFM ;  A7MST3, BIOH_VIBHB ;
DR   Q87TC2, BIOH_VIBPA ;  B7VHH1, BIOH_VIBSL ;  Q8DDU4, BIOH_VIBVU ;
DR   Q7MPY0, BIOH_VIBVY ;  Q8D1X1, BIOH_WIGBR ;  Q8PQE0, BIOH_XANAC ;
DR   Q4UZP1, BIOH_XANC8 ;  B0RMQ9, BIOH_XANCB ;  Q8PDF3, BIOH_XANCP ;
DR   Q2P907, BIOH_XANOM ;  Q5H6D1, BIOH_XANOR ;  B2I9H6, BIOH_XYLF2 ;
DR   Q9PDM3, BIOH_XYLFA ;  B0U6I9, BIOH_XYLFM ;  Q87DT3, BIOH_XYLFT ;
DR   A1JSF8, BIOH_YERE8 ;  A7FNV8, BIOH_YERP3 ;  B2K5V7, BIOH_YERPB ;
DR   Q74Y45, BIOH_YERPE ;  A9R4D0, BIOH_YERPG ;  Q664J8, BIOH_YERPS ;
DR   B1JHZ5, BIOH_YERPY ;
//
ID   3.1.1.86
DE   Rhamnogalacturonan acetylesterase.
AN   RGAE.
CA   Hydrolytic cleavage of 2-O-acetyl- or 3-O-acetyl groups of alpha-D-
CA   galacturonic acid in rhamnogalacturonan I.
CC   -!- The degradation of rhamnogalacturonan by rhamnogalacturonases depends
CC       on the removal of the acetyl esters from the substrate.
DR   Q00017, RHA1_ASPAC ;
//
ID   3.1.1.n1
DE   Transferred entry: 3.5.1.103.
//
ID   3.1.2.1
DE   Acetyl-CoA hydrolase.
AN   Acetyl-CoA acylase.
AN   Acetyl-CoA deacylase.
CA   Acetyl-CoA + H(2)O = CoA + acetate.
DR   Q754Q2, ACH1_ASHGO ;  P83773, ACH1_CANAL ;  Q6FPF3, ACH1_CANGA ;
DR   Q6BKW1, ACH1_DEBHA ;  Q54K91, ACH1_DICDI ;  Q6CNR2, ACH1_KLULA ;
DR   P15937, ACH1_NEUCR ;  Q9UUJ9, ACH1_SCHPO ;  Q6C3Z9, ACH1_YARLI ;
DR   P32316, ACH1_YEAST ;  Q8WYK0, ACO12_HUMAN;  Q9DBK0, ACO12_MOUSE;
DR   Q99NB7, ACO12_RAT  ;
//
ID   3.1.2.2
DE   Palmitoyl-CoA hydrolase.
AN   Long-chain fatty-acyl-CoA hydrolase.
CA   Palmitoyl-CoA + H(2)O = CoA + palmitate.
CC   -!- Also hydrolyzes CoA thioesters of other long-chain fatty acids.
PR   PROSITE; PDOC00112;
DR   Q86TX2, ACOT1_HUMAN;  O55137, ACOT1_MOUSE;  O88267, ACOT1_RAT  ;
DR   P49753, ACOT2_HUMAN;  Q9QYR9, ACOT2_MOUSE;  O55171, ACOT2_RAT  ;
DR   Q9QYR7, ACOT3_MOUSE;  Q8N9L9, ACOT4_HUMAN;  Q8BWN8, ACOT4_MOUSE;
DR   Q6Q2Z6, ACOT5_MOUSE;  Q14032, BAAT_HUMAN ;  Q91X34, BAAT_MOUSE ;
DR   Q63276, BAAT_RAT   ;  Q6ZUV0, BACHL_HUMAN;  O00154, BACH_HUMAN ;
DR   Q91V12, BACH_MOUSE ;  Q64559, BACH_RAT   ;  Q88QS0, ESTP_PSEPK ;
DR   Q93MW7, LIP_STRRM  ;  P80250, PMCH_RAT   ;  P41903, PTE1_YEAST ;
//
ID   3.1.2.3
DE   Succinyl-CoA hydrolase.
AN   Succinyl-CoA acylase.
CA   Succinyl-CoA + H(2)O = CoA + succinate.
//
ID   3.1.2.4
DE   3-hydroxyisobutyryl-CoA hydrolase.
CA   3-hydroxy-2-methylpropanoyl-CoA + H(2)O = CoA + 3-hydroxy-2-
CA   methylpropanoate.
CC   -!- Also hydrolyzes 3-hydroxypropanoyl-CoA.
DR   Q9LKJ1, HIBC1_ARATH;  Q1PEY5, HIBC2_ARATH;  Q6NMB0, HIBC3_ARATH;
DR   Q2HJ73, HIBCH_BOVIN;  Q5ZJ60, HIBCH_CHICK;  Q58EB4, HIBCH_DANRE;
DR   Q55GS6, HIBCH_DICDI;  Q6NVY1, HIBCH_HUMAN;  Q8QZS1, HIBCH_MOUSE;
DR   Q5XIE6, HIBCH_RAT  ;  O74802, HIBCH_SCHPO;  A2VDC2, HIBCH_XENLA;
DR   Q28FR6, HIBCH_XENTR;  P28817, HIBCH_YEAST;
//
ID   3.1.2.5
DE   Hydroxymethylglutaryl-CoA hydrolase.
CA   (S)-3-hydroxy-3-methylglutaryl-CoA + H(2)O = CoA + 3-hydroxy-3-
CA   methylglutarate.
//
ID   3.1.2.6
DE   Hydroxyacylglutathione hydrolase.
AN   Glyoxalase II.
CA   S-(2-hydroxyacyl)glutathione + H(2)O = glutathione + a 2-hydroxy
CA   carboxylate.
CC   -!- Also hydrolyzes S-acetoacetylglutathione, more slowly.
CC   -!- Formerly EC 3.1.2.8.
DR   Q9UT36, GLO21_SCHPO;  Q7MQ55, GLO21_VIBVY;  O94250, GLO22_SCHPO;
DR   Q7MII4, GLO22_VIBVY;  O24496, GLO2C_ARATH;  Q8LDW8, GLO2D_ARATH;
DR   O24495, GLO2M_ARATH;  Q9SID3, GLO2N_ARATH;  Q9C8L4, GLO2O_ARATH;
DR   B0BZI8, GLO2_ACAM1 ;  A5FZE9, GLO2_ACICJ ;  A3MZD3, GLO2_ACTP2 ;
DR   B3H0S9, GLO2_ACTP7 ;  B0BTR9, GLO2_ACTPJ ;  A6VNK4, GLO2_ACTSZ ;
DR   A0KIK2, GLO2_AERHH ;  A4SPI6, GLO2_AERS4 ;  Q8U9W1, GLO2_AGRT5 ;
DR   Q0A751, GLO2_ALHEH ;  B6EJV4, GLO2_ALISL ;  Q2IJC6, GLO2_ANADE ;
DR   Q3MGD2, GLO2_ANAVT ;  Q6G1L3, GLO2_BARHE ;  Q6FYC3, GLO2_BARQU ;
DR   A9IZW8, GLO2_BART1 ;  Q1LT01, GLO2_BAUCH ;  Q6ML19, GLO2_BDEBA ;
DR   Q7VQB7, GLO2_BLOFL ;  Q493H8, GLO2_BLOPB ;  Q3B7M2, GLO2_BOVIN ;
DR   Q89XT5, GLO2_BRAJA ;  A5ETG1, GLO2_BRASB ;  A4YKS8, GLO2_BRASO ;
DR   B2S889, GLO2_BRUA1 ;  Q2YLU8, GLO2_BRUA2 ;  Q57AW2, GLO2_BRUAB ;
DR   A9M8S2, GLO2_BRUC2 ;  C0RFI1, GLO2_BRUMB ;  Q8YJF4, GLO2_BRUME ;
DR   A5VSR1, GLO2_BRUO2 ;  B0CIU0, GLO2_BRUSI ;  Q8FYE7, GLO2_BRUSU ;
DR   P57336, GLO2_BUCAI ;  Q08889, GLO2_BUCAP ;  Q89AN4, GLO2_BUCBP ;
DR   Q28333, GLO2_CALJA ;  Q5ZI23, GLO2_CHICK ;  Q1QW62, GLO2_CHRSD ;
DR   A8AKR2, GLO2_CITK8 ;  Q46Z82, GLO2_CUPPJ ;  B3R1Y0, GLO2_CUPTR ;
DR   B1WUT9, GLO2_CYAA5 ;  B8HMJ9, GLO2_CYAP4 ;  B7KEB4, GLO2_CYAP7 ;
DR   B7K3R6, GLO2_CYAP8 ;  Q6P963, GLO2_DANRE ;  Q47FN7, GLO2_DECAR ;
DR   Q54MR1, GLO2_DICDI ;  A7ZHU8, GLO2_ECO24 ;  B7UJA8, GLO2_ECO27 ;
DR   B7MBI8, GLO2_ECO45 ;  B7LHB8, GLO2_ECO55 ;  P0AC85, GLO2_ECO57 ;
DR   B5Z0I6, GLO2_ECO5E ;  B7NKW6, GLO2_ECO7I ;  B7MQ21, GLO2_ECO81 ;
DR   B7M211, GLO2_ECO8A ;  C4ZRU9, GLO2_ECOBW ;  B1XD76, GLO2_ECODH ;
DR   A7ZWF4, GLO2_ECOHS ;  A1A7Q3, GLO2_ECOK1 ;  Q0TLC5, GLO2_ECOL5 ;
DR   Q8FKY7, GLO2_ECOL6 ;  B1IPU6, GLO2_ECOLC ;  P0AC84, GLO2_ECOLI ;
DR   B7N874, GLO2_ECOLU ;  B6HZS5, GLO2_ECOSE ;  B1LHM1, GLO2_ECOSM ;
DR   Q1RFX9, GLO2_ECOUT ;  C5BEP2, GLO2_EDWI9 ;  Q8SSH0, GLO2_ENCCU ;
DR   A4W6V2, GLO2_ENT38 ;  A7MI37, GLO2_ENTS8 ;  Q6D1V5, GLO2_ERWCT ;
DR   B2VHJ7, GLO2_ERWT9 ;  Q2N9P7, GLO2_ERYLH ;  B7LW87, GLO2_ESCF3 ;
DR   B0TXY0, GLO2_FRAP2 ;  Q14GJ6, GLO2_FRAT1 ;  A7NB16, GLO2_FRATF ;
DR   Q2A4E2, GLO2_FRATH ;  B2SFR3, GLO2_FRATM ;  A0Q7M7, GLO2_FRATN ;
DR   Q0BMS2, GLO2_FRATO ;  Q5NF43, GLO2_FRATT ;  A4IWV0, GLO2_FRATW ;
DR   Q7NG34, GLO2_GLOVI ;  Q7VM19, GLO2_HAEDU ;  Q4QJZ3, GLO2_HAEI8 ;
DR   A5UF43, GLO2_HAEIG ;  P71374, GLO2_HAEIN ;  B8F6A3, GLO2_HAEPS ;
DR   Q0I3Q7, GLO2_HAES1 ;  B0UU01, GLO2_HAES2 ;  Q2SJ47, GLO2_HAHCH ;
DR   A1WXD9, GLO2_HALHL ;  C4K7Z9, GLO2_HAMD5 ;  A4G7G5, GLO2_HERAR ;
DR   Q16775, GLO2_HUMAN ;  Q0BWR4, GLO2_HYPNA ;  Q5QZL0, GLO2_IDILO ;
DR   Q28TK3, GLO2_JANSC ;  B5Y1G4, GLO2_KLEP3 ;  A6T510, GLO2_KLEP7 ;
DR   Q5X5R2, GLO2_LEGPA ;  A5IBE7, GLO2_LEGPC ;  Q5ZVZ3, GLO2_LEGPH ;
DR   Q5WX41, GLO2_LEGPL ;  Q04RQ6, GLO2_LEPBJ ;  Q051W5, GLO2_LEPBL ;
DR   Q4R6C1, GLO2_MACFA ;  Q65U07, GLO2_MANSM ;  A1U0V1, GLO2_MARAV ;
DR   Q0AM20, GLO2_MARMM ;  A6VVZ9, GLO2_MARMS ;  Q11DS3, GLO2_MESSB ;
DR   Q60BX0, GLO2_METCA ;  Q1H188, GLO2_METFK ;  B8ICA2, GLO2_METNO ;
DR   B0UBD0, GLO2_METS4 ;  B0JW10, GLO2_MICAN ;  Q99KB8, GLO2_MOUSE ;
DR   Q5F7J0, GLO2_NEIG1 ;  B4RJC7, GLO2_NEIG2 ;  A9M0M3, GLO2_NEIM0 ;
DR   A1IPQ8, GLO2_NEIMA ;  Q9JXK4, GLO2_NEIMB ;  A1KW76, GLO2_NEIMF ;
DR   Q0AE32, GLO2_NITEC ;  Q82XW0, GLO2_NITEU ;  Q1QQZ1, GLO2_NITHX ;
DR   Q3JAC4, GLO2_NITOC ;  Q3SVQ1, GLO2_NITWN ;  B2IVH7, GLO2_NOSP7 ;
DR   Q8YZ99, GLO2_NOSS1 ;  A6WXE0, GLO2_OCHA4 ;  Q9CMW8, GLO2_PASMU ;
DR   C6DC67, GLO2_PECCP ;  Q4FP49, GLO2_PELUB ;  Q7N809, GLO2_PHOLL ;
DR   Q6LN63, GLO2_PHOPR ;  Q12BV7, GLO2_POLSJ ;  A3PBT3, GLO2_PROM0 ;
DR   A2C116, GLO2_PROM1 ;  A2C7W3, GLO2_PROM3 ;  A9BEI3, GLO2_PROM4 ;
DR   Q31BX5, GLO2_PROM9 ;  Q7VD23, GLO2_PROMA ;  Q7V6G8, GLO2_PROMM ;
DR   A2BQ40, GLO2_PROMS ;  Q46GM1, GLO2_PROMT ;  Q48KX8, GLO2_PSE14 ;
DR   A6V707, GLO2_PSEA7 ;  B7VB64, GLO2_PSEA8 ;  Q9I2T1, GLO2_PSEAE ;
DR   Q1I7T2, GLO2_PSEE4 ;  Q4KBH9, GLO2_PSEF5 ;  C3K9Q0, GLO2_PSEFS ;
DR   Q3IIR9, GLO2_PSEHT ;  A4XU09, GLO2_PSEMY ;  A5W167, GLO2_PSEP1 ;
DR   Q3KE79, GLO2_PSEPF ;  B0KN02, GLO2_PSEPG ;  Q88FF3, GLO2_PSEPK ;
DR   B1JBN3, GLO2_PSEPW ;  Q87YS8, GLO2_PSESM ;  Q4ZVL3, GLO2_PSEU2 ;
DR   A1SS88, GLO2_PSYIN ;  Q1LL91, GLO2_RALME ;  O35952, GLO2_RAT   ;
DR   Q2K3M6, GLO2_RHIEC ;  Q1MB56, GLO2_RHIL3 ;  Q98G02, GLO2_RHILO ;
DR   Q92MF8, GLO2_RHIME ;  P05446, GLO2_RHOBL ;  P96981, GLO2_RHOCA ;
DR   Q21YF8, GLO2_RHOFD ;  Q2J429, GLO2_RHOP2 ;  Q07VA9, GLO2_RHOP5 ;
DR   Q6NC62, GLO2_RHOPA ;  Q21C03, GLO2_RHOPB ;  Q13F06, GLO2_RHOPS ;
DR   Q2RP80, GLO2_RHORT ;  A3PIB4, GLO2_RHOS1 ;  Q3J436, GLO2_RHOS4 ;
DR   A4WUN2, GLO2_RHOS5 ;  Q162S3, GLO2_ROSDO ;  Q21J46, GLO2_SACD2 ;
DR   B5F8X0, GLO2_SALA4 ;  A9MPF3, GLO2_SALAR ;  Q57SZ8, GLO2_SALCH ;
DR   B5FJ56, GLO2_SALDC ;  B5R447, GLO2_SALEP ;  B5R5L1, GLO2_SALG2 ;
DR   B4TK83, GLO2_SALHS ;  B4SV37, GLO2_SALNS ;  Q5PFD6, GLO2_SALPA ;
DR   A9MZ21, GLO2_SALPB ;  C0Q6N0, GLO2_SALPC ;  B5BDW7, GLO2_SALPK ;
DR   B4TYG8, GLO2_SALSV ;  Q8Z983, GLO2_SALTI ;  Q8ZRM2, GLO2_SALTY ;
DR   Q26547, GLO2_SCHMA ;  A8GA75, GLO2_SERP5 ;  A1S6T3, GLO2_SHEAM ;
DR   B8E5A2, GLO2_SHEB2 ;  A3D437, GLO2_SHEB5 ;  A6WMW5, GLO2_SHEB8 ;
DR   A9L0E9, GLO2_SHEB9 ;  Q12MM2, GLO2_SHEDO ;  B0TRL8, GLO2_SHEHH ;
DR   A3QET2, GLO2_SHELP ;  Q8EE27, GLO2_SHEON ;  A8H589, GLO2_SHEPA ;
DR   A4Y6B8, GLO2_SHEPC ;  A0KXS9, GLO2_SHESA ;  A1RK78, GLO2_SHESW ;
DR   B2U350, GLO2_SHIB3 ;  Q325T4, GLO2_SHIBS ;  Q32JQ1, GLO2_SHIDS ;
DR   Q0T802, GLO2_SHIF8 ;  Q83MC1, GLO2_SHIFL ;  Q3Z5F1, GLO2_SHISS ;
DR   Q5LNN5, GLO2_SILPO ;  Q2NVG1, GLO2_SODGM ;  B4SLN7, GLO2_STRM5 ;
DR   B2FR57, GLO2_STRMK ;  Q31ND6, GLO2_SYNE7 ;  Q2JVC3, GLO2_SYNJA ;
DR   Q2JPX4, GLO2_SYNJB ;  B1XQ70, GLO2_SYNP2 ;  Q5N5S6, GLO2_SYNP6 ;
DR   A5GJK5, GLO2_SYNPW ;  Q7U5Z8, GLO2_SYNPX ;  Q0I8S8, GLO2_SYNS3 ;
DR   Q3AYI2, GLO2_SYNS9 ;  Q3AL08, GLO2_SYNSC ;  P72933, GLO2_SYNY3 ;
DR   Q8DIF1, GLO2_THEEB ;  Q31H51, GLO2_THICR ;  Q3SIB0, GLO2_THIDA ;
DR   C4LC58, GLO2_TOLAT ;  Q10Y41, GLO2_TRIEI ;  A5F635, GLO2_VIBC3 ;
DR   Q9KPX6, GLO2_VIBCH ;  C3LPP0, GLO2_VIBCM ;  Q5E3G3, GLO2_VIBF1 ;
DR   B5F9V3, GLO2_VIBFM ;  A7MY07, GLO2_VIBHB ;  Q87MG0, GLO2_VIBPA ;
DR   B7VIP5, GLO2_VIBSL ;  Q8DBD8, GLO2_VIBVU ;  Q8D3D4, GLO2_WIGBR ;
DR   Q8PNI0, GLO2_XANAC ;  Q3BWP5, GLO2_XANC5 ;  Q4URM1, GLO2_XANC8 ;
DR   B0RTE9, GLO2_XANCB ;  Q8PBY0, GLO2_XANCP ;  Q2P6Y4, GLO2_XANOM ;
DR   B4F6K2, GLO2_XENTR ;  B2I5S5, GLO2_XYLF2 ;  Q9PBI4, GLO2_XYLFA ;
DR   B0U365, GLO2_XYLFM ;  Q87C74, GLO2_XYLFT ;  Q05584, GLO2_YEAST ;
DR   A1JKA9, GLO2_YERE8 ;  A7FFK5, GLO2_YERP3 ;  Q1CAJ7, GLO2_YERPA ;
DR   B2KAD1, GLO2_YERPB ;  Q0WHW5, GLO2_YERPE ;  Q1CFI4, GLO2_YERPN ;
DR   A4TL56, GLO2_YERPP ;  Q667M5, GLO2_YERPS ;  B1JR44, GLO2_YERPY ;
DR   Q12320, GLO4_YEAST ;
//
ID   3.1.2.7
DE   Glutathione thiolesterase.
AN   Glutathione thioesterase.
CA   S-acylglutathione + H(2)O = glutathione + a carboxylate.
//
ID   3.1.2.8
DE   Transferred entry: 3.1.2.6.
//
ID   3.1.2.9
DE   Deleted entry.
//
ID   3.1.2.10
DE   Formyl-CoA hydrolase.
CA   Formyl-CoA + H(2)O = CoA + formate.
//
ID   3.1.2.11
DE   Acetoacetyl-CoA hydrolase.
CA   Acetoacetyl-CoA + H(2)O = CoA + acetoacetate.
//
ID   3.1.2.12
DE   S-formylglutathione hydrolase.
CA   S-formylglutathione + H(2)O = glutathione + formate.
CC   -!- Also hydrolyzes S-acetylglutathione, more slowly.
DR   Q08E20, ESTD_BOVIN ;  P10768, ESTD_HUMAN ;  Q9R0P3, ESTD_MOUSE ;
DR   Q9GJT2, ESTD_PIG   ;  B0BNE5, ESTD_RAT   ;  A7ZIA3, SFGH1_ECO24;
DR   Q8X5J5, SFGH1_ECO57;  B1XEU8, SFGH1_ECODH;  A7ZX03, SFGH1_ECOHS;
DR   A1A834, SFGH1_ECOK1;  Q0TKS8, SFGH1_ECOL5;  Q8FKG2, SFGH1_ECOL6;
DR   B1J086, SFGH1_ECOLC;  P51025, SFGH1_ECOLI;  B1LIP0, SFGH1_ECOSM;
DR   Q1RFI8, SFGH1_ECOUT;  Q3Z551, SFGH1_SHISS;  A7ZNX7, SFGH2_ECO24;
DR   Q8X635, SFGH2_ECO57;  B1X7P2, SFGH2_ECODH;  A8A215, SFGH2_ECOHS;
DR   A1AD14, SFGH2_ECOK1;  Q0TFT6, SFGH2_ECOL5;  Q8FFU3, SFGH2_ECOL6;
DR   B1IYB5, SFGH2_ECOLC;  P33018, SFGH2_ECOLI;  B1LKQ1, SFGH2_ECOSM;
DR   Q1R9R8, SFGH2_ECOUT;  Q31YW2, SFGH2_SHIBS;  Q32EQ3, SFGH2_SHIDS;
DR   Q0T2X0, SFGH2_SHIF8;  Q3Z052, SFGH2_SHISS;  Q8LAS8, SFGH_ARATH ;
DR   P44556, SFGH_HAEIN ;  A1AXZ2, SFGH_PARDP ;  P40363, SFGH_YEAST ;
//
ID   3.1.2.13
DE   S-succinylglutathione hydrolase.
CA   S-succinylglutathione + H(2)O = glutathione + succinate.
//
ID   3.1.2.14
DE   Oleoyl-[acyl-carrier-protein] hydrolase.
AN   Acyl-[acyl-carrier-protein] hydrolase.
AN   S-acyl fatty acid synthase thioesterase.
CA   Oleoyl-[acyl-carrier-protein] + H(2)O = [acyl-carrier-protein] + oleate.
CC   -!- Acts on [acyl-carrier-protein] thioesters of fatty acids from C(12)
CC       to C(18), but the derivative of oleic acid is hydrolyzed much more
CC       rapidly than any other compound tested.
DR   P34731, FAS1_CANAL ;  Q9UUG0, FAS1_SCHPO ;  P34229, FAS1_YARLI ;
DR   P07149, FAS1_YEAST ;  Q71SP7, FAS_BOVIN  ;  P12276, FAS_CHICK  ;
DR   P49327, FAS_HUMAN  ;  P19096, FAS_MOUSE  ;  P12785, FAS_RAT    ;
DR   Q42712, FATA_CORSA ;  P00633, SAST_ANAPL ;  Q9NV23, SAST_HUMAN ;
DR   Q8R197, SAST_MOUSE ;  P08635, SAST_RAT   ;  Q92215, TOXC_COCCA ;
//
ID   3.1.2.15
DE   Ubiquitin thiolesterase.
AN   Ubiquitin carboxy-terminal esterase.
AN   Ubiquitin carboxy-terminal hydrolase.
AN   Ubiquitin thioesterase.
CA   Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.
CC   -!- Acts on esters formed between thiols such as dithiothreitol or
CC       glutathione and the C-terminal glycine residue of the polypeptide
CC       ubiquitin.
CC   -!- Also acts on AMP-ubiquitin.
PR   PROSITE; PDOC00127;
PR   PROSITE; PDOC00750;
//
ID   3.1.2.16
DE   Citrate-lyase deacetylase.
AN   [Citrate-(pro-3S)-lyase] thioesterase.
AN   [Citrate-(pro-3S)-lyase] thiolesterase.
AN   Acetyl-S-(acyl-carrier protein) enzyme thioester hydrolase.
AN   Citrate lyase deacetylase.
CA   [Citrate (pro-3S)-lyase](acetyl form) + 6 H(2)O = [citrate (pro-3S)-
CA   lyase](thiol form) + 6 acetate.
CC   -!- In the proteobacterium Rubrivivax gelatinosus, this enzyme modulates
CC       the activity of EC 4.1.3.6 by converting it from its active acetyl
CC       form into its inactive thiol form by removal of its acetyl groups.
CC   -!- The activity of citrate-lyase deacetylase is itself inhibited by
CC       L-glutamate.
//
ID   3.1.2.17
DE   (S)-methylmalonyl-CoA hydrolase.
CA   (S)-methylmalonyl-CoA + H(2)O = methylmalonate + CoA.
//
ID   3.1.2.18
DE   ADP-dependent short-chain-acyl-CoA hydrolase.
CA   Acyl-CoA + H(2)O = CoA + a carboxylate.
CC   -!- Requires ADP; inhibited by NADH.
CC   -!- Maximum activity is shown with propanoyl-CoA.
//
ID   3.1.2.19
DE   ADP-dependent medium-chain-acyl-CoA hydrolase.
CA   Acyl-CoA + H(2)O = CoA + a carboxylate.
CC   -!- Requires ADP; inhibited by NADH.
CC   -!- Maximum activity is shown with nonanoyl-CoA.
//
ID   3.1.2.20
DE   Acyl-CoA hydrolase.
CA   Acyl-CoA + H(2)O = CoA + a carboxylate.
CC   -!- Broad specificity for medium- to long-chain acyl-CoA.
CC   -!- Insensitive to NAD(+) (cf. EC 3.1.2.19).
//
ID   3.1.2.21
DE   Dodecanoyl-[acyl-carrier-protein] hydrolase.
AN   Dodecanoyl-acyl-carrier-protein hydrolase.
AN   Dodecyl-[acyl-carrier protein] hydrolase.
AN   Lauryl-[acyl-carrier protein] hydrolase.
CA   Dodecanoyl-[acyl-carrier-protein] + H(2)O = [acyl-carrier-protein] +
CA   dodecanoate.
CC   -!- Acts on the acyl-carrier protein thioester of C(12) and, with a much
CC       lower activity, C(14) fatty acids.
CC   -!- The derivative of oleic acid is hydrolyzed very slowly.
//
ID   3.1.2.22
DE   Palmitoyl-protein hydrolase.
AN   Palmitoyl-protein thioesterase.
CA   Palmitoyl-protein + H(2)O = palmitate + protein.
CC   -!- Specific for long-chain thioesters of fatty acids.
CC   -!- Hydrolyzes fatty acids from S-acylated cysteine residues in proteins,
CC       palmitoyl cysteine and palmitoyl-CoA.
DR   O59747, PDF1_SCHPO ;  P45478, PPT1_BOVIN ;  Q20390, PPT1_CAEEL ;
DR   Q9W3C7, PPT1_DROME ;  P50897, PPT1_HUMAN ;  Q8HXW6, PPT1_MACFA ;
DR   O88531, PPT1_MOUSE ;  P45479, PPT1_RAT   ;  Q54CM0, PPT3_DICDI ;
//
ID   3.1.2.23
DE   4-hydroxybenzoyl-CoA thioesterase.
CA   4-hydroxybenzoyl-CoA + H(2)O = 4-hydroxybenzoate + CoA.
CC   -!- This enzyme is part of the bacterial 2,4-dichlorobenzoate degradation
CC       pathway.
PR   PROSITE; PDOC01031;
DR   Q7BI34, 4HBT_ARTGO ;  Q04416, 4HBT_ARTSP ;  P56653, 4HBT_PSEUC ;
//
ID   3.1.2.24
DE   Transferred entry: 3.13.1.3.
//
ID   3.1.2.25
DE   Phenylacetyl-CoA hydrolase.
CA   Phenylglyoxylyl-CoA + H(2)O = phenylglyoxylate + CoA.
CC   -!- This is the second step in the conversion of phenylacetyl-CoA to
CC       phenylglyoxylate, the first step being carried out by EC 1.17.5.1.
//
ID   3.1.2.26
DE   Bile-acid-CoA hydrolase.
AN   Bile acid-coenzyme A hydrolase.
CA   Deoxycholoyl-CoA + H(2)O = CoA + deoxycholate.
CC   -!- Choloyl-CoA, 3-dehydrocholoyl-CoA and chenodeoxycholoyl-CoA can also
CC       act as substrates, but acetyl-CoA, isovaleryl-CoA, palmitoyl-CoA and
CC       phenylacetyl-CoA cannot.
DR   P19413, BAIF_EUBSP ;
//
ID   3.1.2.27
DE   Choloyl-CoA hydrolase.
AN   Chenodeoxycholoyl-coenzyme A thioesterase.
AN   Choloyl-coenzyme A thioesterase.
AN   Peroxisomal acyl-CoA thioesterase 2.
AN   PTE-2.
CA   Choloyl-CoA + H(2)O = cholate + CoA.
CC   -!- Also acts on chenodeoxycholoyl-CoA and to a lesser extent on short-
CC       and medium- to long-chain acyl-CoA's, and other substrates, including
CC       trihydroxycoprostanoyl-CoA, hydroxymethylglutaryl-CoA and branched
CC       chain acyl-CoA's, all of which are present in peroxisomes.
CC   -!- The enzyme is strongly inhibited by CoA and may be involved in
CC       controlling CoA levels in the peroxisome.
DR   O14734, ACOT8_HUMAN;  P58137, ACOT8_MOUSE;  Q8VHK0, ACOT8_RAT  ;
//
ID   3.1.2.28
DE   1,4-dihydroxy-2-naphthoyl-CoA hydrolase.
CA   1,4-dihydroxy-2-naphthoyl-CoA + H(2)O = 1,4-dihydroxy-2-naphthoate + CoA.
CC   -!- This enzyme participates in the synthesis of menaquinones,
CC       phyloquinone, as well as several plant pigments.
CC   -!- The enzyme from the cyanobacterium Synechocystis sp. PCC 6803 does
CC       not accept benzoyl-CoA or phenylacetyl-CoA as substrates.
CC   -!- Formerly EC 3.1.2.n1.
DR   B0CEN8, DNCH_ACAM1 ;  Q3MG63, DNCH_ANAVT ;  B1WZN0, DNCH_CYAA5 ;
DR   B7KDA3, DNCH_CYAP7 ;  B7JXS8, DNCH_CYAP8 ;  B0JQL4, DNCH_MICAN ;
DR   B2IZ83, DNCH_NOSP7 ;  Q8YU89, DNCH_NOSS1 ;  A3PAP1, DNCH_PROM0 ;
DR   A2C002, DNCH_PROM1 ;  A8G2H9, DNCH_PROM2 ;  A2CDA0, DNCH_PROM3 ;
DR   A9BD34, DNCH_PROM4 ;  A2BUF0, DNCH_PROM5 ;  Q31D08, DNCH_PROM9 ;
DR   Q7VE16, DNCH_PROMA ;  Q7V4A7, DNCH_PROMM ;  Q7V3A9, DNCH_PROMP ;
DR   A2BNW8, DNCH_PROMS ;  Q46HJ9, DNCH_PROMT ;  Q31ME5, DNCH_SYNE7 ;
DR   B1XL26, DNCH_SYNP2 ;  Q5MZI3, DNCH_SYNP6 ;  A5GP76, DNCH_SYNPW ;
DR   Q7U3X6, DNCH_SYNPX ;  A5GWA0, DNCH_SYNR3 ;  Q0I6T4, DNCH_SYNS3 ;
DR   Q3AVZ5, DNCH_SYNS9 ;  Q3AGW5, DNCH_SYNSC ;  Q55777, DNCH_SYNY3 ;
DR   Q8DLK3, DNCH_THEEB ;  Q10XE8, DNCH_TRIEI ;
//
ID   3.1.2.29
DE   Fluoroacetyl-CoA thioesterase.
CA   Fluoroacetyl-CoA + H(2)O = fluoroacetate + CoA.
CC   -!- Fluoroacetate is extremely toxic.
CC   -!- It reacts with CoA to form fluoroacetyl-CoA, which substitutes for
CC       acetyl CoA and reacts with EC 2.3.3.1 to produce fluorocitrate,
CC       a metabolite of which binds very tightly to EC 4.2.1.3 and halts the
CC       TCA cycle.
CC   -!- This enzyme hydrolyzes fluoroacetyl-CoA before it can react with
CC       citrate synthase, and thus confers fluoroacetate resistance on the
CC       organisms that produce it.
CC   -!- It has been described in the poisonous plant Dichapetalum cymosum and
CC       the bacterium Streptomyces cattleya, both of which are fluoroacetate
CC       producers.
//
ID   3.1.2.n1
DE   Transferred entry: 3.1.2.28.
//
ID   3.1.3.1
DE   Alkaline phosphatase.
AN   Alkaline phosphomonoesterase.
AN   Glycerophosphatase.
AN   Phosphomonoesterase.
CA   A phosphate monoester + H(2)O = an alcohol + phosphate.
CF   Magnesium; Zinc.
CC   -!- Active at a high pH optimum.
CC   -!- Wide specificity.
CC   -!- Also catalyzes transphosphorylations.
CC   -!- Some enzymes hydrolase diphosphate (cf. EC 3.6.1.1).
PR   PROSITE; PDOC00113;
DR   P86348, ALPH_AGKAC ;  A1YYW7, ALPH_SPHSX ;  Q24238, APH4_DROME ;
DR   P05187, PPB1_HUMAN ;  P81800, PPB1_PREIN ;  P19405, PPB3_BACSU ;
DR   P19406, PPB4_BACSU ;  P42251, PPBD_BACSU ;  P24823, PPBE_MOUSE ;
DR   P35483, PPBH_PSEAE ;  P15693, PPBI1_RAT  ;  P51740, PPBI2_RAT  ;
DR   P19111, PPBI_BOVIN ;  P09923, PPBI_HUMAN ;  P24822, PPBI_MOUSE ;
DR   P35482, PPBL_PSEAE ;  P10696, PPBN_HUMAN ;  P09487, PPBT_BOVIN ;
DR   Q92058, PPBT_CHICK ;  Q29486, PPBT_FELCA ;  P05186, PPBT_HUMAN ;
DR   P09242, PPBT_MOUSE ;  P08289, PPBT_RAT   ;  P29523, PPB_BOMMO  ;
DR   P00634, PPB_ECOLI  ;  P21948, PPB_ESCF3  ;  P83456, PPB_GADMO  ;
DR   Q05205, PPB_LYSEN  ;  O60109, PPB_SCHPO  ;  P19147, PPB_SERMA  ;
DR   P11491, PPB_YEAST  ;
//
ID   3.1.3.2
DE   Acid phosphatase.
AN   Acid phosphomonoesterase.
AN   Glycerophosphatase.
AN   Phosphomonoesterase.
CA   A phosphate monoester + H(2)O = an alcohol + phosphate.
CC   -!- Wide specificity.
CC   -!- Also catalyzes transphosphorylations.
PR   PROSITE; PDOC00538;
PR   PROSITE; PDOC00891;
DR   Q619N4, ACP1_CAEBR ;  Q23534, ACP1_CAEEL ;  Q5BLY5, ACPH1_APIME;
DR   Q6DH46, ACPL2_DANRE;  Q8TE99, ACPL2_HUMAN;  Q8BHA9, ACPL2_MOUSE;
DR   Q66H78, ACPL2_RAT  ;  Q0IHQ9, ACPL2_XENTR;  P0AE22, APHA_ECOLI ;
DR   P44009, APHA_HAEIN ;  Q59544, APHA_MORMO ;  P56527, APHA_PROMI ;
DR   O08430, APHA_SALTI ;  P58683, APHA_SALTY ;  P0AE23, APHA_SHIFL ;
DR   A5D6U8, PAPL_DANRE ;  Q6ZNF0, PAPL_HUMAN ;  Q8BX37, PAPL_MOUSE ;
DR   Q09448, PHO10_CAEEL;  Q09451, PHO11_CAEEL;  P30887, PHO2_YARLI ;
DR   Q10944, PHO5_CAEEL ;  Q8X176, PHOA_ASPFU ;  P34724, PHOA_ASPNG ;
DR   P37274, PHOA_PENCH ;  P28581, PHOC_MORMO ;  P26975, PHON_PROST ;
DR   Q934J6, PHON_SALTI ;  P26976, PHON_SALTY ;  P08540, PHOX_KLULA ;
DR   Q9SIV9, PPA10_ARATH;  Q9SI18, PPA11_ARATH;  Q38924, PPA12_ARATH;
DR   O48840, PPA13_ARATH;  Q9SFU3, PPA15_ARATH;  Q9SCX8, PPA17_ARATH;
DR   Q9LJU7, PPA18_ARATH;  Q9LX83, PPA19_ARATH;  P20584, PPA1_ASPNG ;
DR   P52291, PPA1_PICPA ;  P08091, PPA1_SCHPO ;  P27061, PPA1_SOLLC ;
DR   Q9LXI7, PPA20_ARATH;  Q9LXI4, PPA21_ARATH;  Q8S340, PPA22_ARATH;
DR   Q6TPH1, PPA23_ARATH;  O23244, PPA25_ARATH;  Q949Y3, PPA26_ARATH;
DR   Q01682, PPA2_SCHPO ;  Q8H129, PPA3_ARATH ;  O60172, PPA3_SCHPO ;
DR   P24031, PPA3_YEAST ;  Q8VYU7, PPA4_ARATH ;  Q9USS6, PPA4_SCHPO ;
DR   Q9C927, PPA5_ARATH ;  P13686, PPA5_HUMAN ;  P52289, PPA5_KLULA ;
DR   Q05117, PPA5_MOUSE ;  P09889, PPA5_PIG   ;  O97860, PPA5_RABIT ;
DR   P29288, PPA5_RAT   ;  P00635, PPA5_YEAST ;  Q9C510, PPA6_ARATH ;
DR   Q9NPH0, PPA6_HUMAN ;  Q8BP40, PPA6_MOUSE ;  Q5R8C0, PPA6_PONAB ;
DR   Q8S341, PPA7_ARATH ;  Q8VYZ2, PPA8_ARATH ;  P35842, PPAB_YEAST ;
DR   P82890, PPAC1_DROME;  P82891, PPAC2_DROME;  P11064, PPAC_BOVIN ;
DR   Q5ZKG5, PPAC_CHICK ;  Q55GW2, PPAC_DICDI ;  P24666, PPAC_HUMAN ;
DR   Q9D358, PPAC_MOUSE ;  P81693, PPAC_PIG   ;  Q5REM7, PPAC_PONAB ;
DR   P41498, PPAC_RAT   ;  P38693, PPAC_YEAST ;  P52290, PPAD_YEAST ;
DR   Q9SE00, PPAF1_IPOBA;  Q9SDZ9, PPAF2_IPOBA;  P80366, PPAF_PHAVU ;
DR   Q09131, PPAF_SOYBN ;  Q0P5F0, PPAL_BOVIN ;  P11117, PPAL_HUMAN ;
DR   Q4R5N9, PPAL_MACFA ;  P24638, PPAL_MOUSE ;  Q5NVF6, PPAL_PONAB ;
DR   P20611, PPAL_RAT   ;  P41893, PPAL_SCHPO ;  B1H1P9, PPAL_XENLA ;
DR   P40347, PPAL_YEAST ;  A6H730, PPAP_BOVIN ;  P15309, PPAP_HUMAN ;
DR   Q8CE08, PPAP_MOUSE ;  P20646, PPAP_RAT   ;  Q9BZG2, PPAT_HUMAN ;
DR   Q3KQG9, PPAT_XENLA ;  Q09549, PPAX_CAEEL ;  Q12546, PPA_ASPFI  ;
DR   P07102, PPA_ECOLI  ;  P14924, PPA_ZYMMO  ;  P83380, PPH1_SOLLC ;
DR   P83379, PPH2_SOLLC ;  Q54P72, Y4753_DICDI;  Q54P71, Y4755_DICDI;
//
ID   3.1.3.3
DE   Phosphoserine phosphatase.
CA   O-phospho-L(or D)-serine + H(2)O = L(or D)-serine + phosphate.
DR   Q3ZBF9, PLPP_BOVIN ;  Q96GD0, PLPP_HUMAN ;  P60487, PLPP_MOUSE ;
DR   Q8VD52, PLPP_RAT   ;  O07014, RSBP_BACSU ;  P40399, RSBU_BACSU ;
DR   P17906, RSBX_BACSU ;  O82796, SERB_ARATH ;  O28142, SERB_ARCFU ;
DR   Q2KHU0, SERB_BOVIN ;  Q9VSY6, SERB_DROME ;  P0AGB1, SERB_ECO57 ;
DR   P0AGB0, SERB_ECOLI ;  P44997, SERB_HAEIN ;  P78330, SERB_HUMAN ;
DR   Q58989, SERB_METJA ;  Q99LS3, SERB_MOUSE ;  A0QJI1, SERB_MYCA1 ;
DR   Q5RB83, SERB_PONAB ;  Q5M819, SERB_RAT   ;  O74382, SERB_SCHPO ;
DR   P0AGB2, SERB_SHIFL ;  P42941, SERB_YEAST ;  Q3T0M0, VPS29_BOVIN;
DR   Q5ZIL2, VPS29_CHICK;  Q7ZV68, VPS29_DANRE;  Q54IF7, VPS29_DICDI;
DR   Q9UBQ0, VPS29_HUMAN;  Q9QZ88, VPS29_MOUSE;  Q5R9Z1, VPS29_PONAB;
DR   B2RZ78, VPS29_RAT  ;  Q6GP62, VPS29_XENLA;  Q6DEU3, VPS29_XENTR;
//
ID   3.1.3.4
DE   Phosphatidate phosphatase.
AN   Lipin.
AN   Phosphatic acid phosphatase.
AN   Phosphatic acid phosphohydrolase.
AN   Phosphatidic acid phospphatase.
CA   A 1,2-diacylglycerol 3-phosphate + H(2)O = a 1,2-diacyl-sn-glycerol +
CA   phosphate.
CF   Magnesium.
CC   -!- This enzyme catalyzes the Mg(2+)-dependent dephosphorylation of a
CC       1,2-diacylglycerol-3-phosphate, yielding a 1,2-diacyl-sn-glycerol
CC       (DAG), the substrate for de novo lipid synthesis via the Kennedy
CC       pathway and for the synthesis of triacylglycerol.
CC   -!- In lipid signaling, the enzyme generates a pool of DAG to be used for
CC       protein kinase C activation.
CC   -!- The mammalian enzymes are known as lipins.
DR   Q9UUA6, DPP1_SCHPO ;  Q05521, DPP1_YEAST ;  Q14693, LPIN1_HUMAN;
DR   Q91ZP3, LPIN1_MOUSE;  Q92539, LPIN2_HUMAN;  Q99PI5, LPIN2_MOUSE;
DR   Q9BQK8, LPIN3_HUMAN;  Q99PI4, LPIN3_MOUSE;  Q7TNN8, LPIN3_MUSSP;
DR   O88956, LPP1_CAVPO ;  O14494, LPP1_HUMAN ;  Q61469, LPP1_MOUSE ;
DR   P60588, LPP1_PIG   ;  O08564, LPP1_RAT   ;  Q04396, LPP1_YEAST ;
DR   Q2HJ61, LPP2_BOVIN ;  O43688, LPP2_HUMAN ;  Q9DAX2, LPP2_MOUSE ;
DR   Q8K593, LPP2_RAT   ;  Q3SZE3, LPP3_BOVIN ;  O14495, LPP3_HUMAN ;
DR   Q99JY8, LPP3_MOUSE ;  P97544, LPP3_RAT   ;  Q29RT8, LPPR2_BOVIN;
DR   Q96GM1, LPPR2_HUMAN;  Q8VCY8, LPPR2_MOUSE;  Q6W5G4, LPPR2_RAT  ;
DR   Q6T4P5, LPPR3_HUMAN;  Q7TPB0, LPPR3_MOUSE;  Q7TMB0, LPPR3_RAT  ;
DR   Q7Z2D5, LPPR4_HUMAN;  Q7TME0, LPPR4_MOUSE;  Q7TMB7, LPPR4_RAT  ;
DR   P32567, PAH1_YEAST ;  Q5VZY2, PPC1A_HUMAN;  Q0VBU9, PPC1A_MOUSE;
DR   Q8NEB5, PPC1B_HUMAN;  Q3UMZ3, PPC1B_MOUSE;  Q6GQ62, PPC1B_XENLA;
DR   Q9V576, WUN_DROME  ;
//
ID   3.1.3.5
DE   5'-nucleotidase.
CA   A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.
CC   -!- Wide specificity for 5'-nucleotides.
PR   PROSITE; PDOC00627;
DR   Q7ZWS2, 5N3LA_XENLA;  Q2TAG6, 5N3LB_XENLA;  Q9BXI3, 5NT1A_HUMAN;
DR   A3KFX0, 5NT1A_MOUSE;  Q96P26, 5NT1B_HUMAN;  Q91YE9, 5NT1B_MOUSE;
DR   Q5ZKF6, 5NT3L_CHICK;  Q969T7, 5NT3L_HUMAN;  Q3UFY7, 5NT3L_MOUSE;
DR   Q6AYP7, 5NT3L_RAT  ;  Q09315, 5NT3_CAEEL ;  Q5ZID6, 5NT3_CHICK ;
DR   Q7SYN4, 5NT3_DANRE ;  Q9H0P0, 5NT3_HUMAN ;  Q9D020, 5NT3_MOUSE ;
DR   O46411, 5NTC_BOVIN ;  Q5ZIZ4, 5NTC_CHICK ;  Q54XC1, 5NTC_DICDI ;
DR   P49902, 5NTC_HUMAN ;  Q3V1L4, 5NTC_MOUSE ;  Q5RA22, 5NTC_PONAB ;
DR   Q6DKB0, 5NTC_XENLA ;  Q5EBF1, 5NTC_XENTR ;  P52307, 5NTD_BOOMI ;
DR   Q05927, 5NTD_BOVIN ;  P29240, 5NTD_DISOM ;  P44569, 5NTD_HAEIN ;
DR   P21589, 5NTD_HUMAN ;  Q9XZ43, 5NTD_LUTLO ;  Q61503, 5NTD_MOUSE ;
DR   Q9I767, 5NTD_PSEAE ;  P21588, 5NTD_RAT   ;  O83142, 5NTD_TREPA ;
DR   Q9KQ30, 5NTD_VIBCH ;  P22848, 5NTD_VIBPA ;  Q8DFG4, 5NTD_VIBVU ;
DR   O34313, NTPES_BACSU;  P15309, PPAP_HUMAN ;  Q8CE08, PPAP_MOUSE ;
DR   P20646, PPAP_RAT   ;  Q390V3, SURE1_BURS3;  Q823A6, SURE1_CHLCV;
DR   Q8ZU79, SURE1_PYRAE;  Q72H70, SURE1_THET2;  Q39FP8, SURE2_BURS3;
DR   Q823A7, SURE2_CHLCV;  Q8ZSY4, SURE2_PYRAE;  Q746M5, SURE2_THET2;
DR   B0C6V3, SURE_ACAM1 ;  Q6FCV6, SURE_ACIAD ;  B7GZ27, SURE_ACIB3 ;
DR   B7I4K2, SURE_ACIB5 ;  B2HVM9, SURE_ACIBC ;  B0VUE2, SURE_ACIBS ;
DR   A3M7F7, SURE_ACIBT ;  B0VBZ1, SURE_ACIBY ;  B9MFW6, SURE_ACIET ;
DR   A3N3M1, SURE_ACTP2 ;  B3H2Z8, SURE_ACTP7 ;  B0BTK8, SURE_ACTPJ ;
DR   A6VLU0, SURE_ACTSZ ;  A0KGH8, SURE_AERHH ;  Q9YDW8, SURE_AERPE ;
DR   A4SRB6, SURE_AERS4 ;  B9JEH2, SURE_AGRRK ;  Q8UEQ3, SURE_AGRT5 ;
DR   B9JXD7, SURE_AGRVS ;  Q0A7L4, SURE_ALHEH ;  A6TRH0, SURE_ALKMQ ;
DR   B8JDR1, SURE_ANAD2 ;  Q2INZ4, SURE_ANADE ;  A7H8F6, SURE_ANADF ;
DR   B9KI89, SURE_ANAMF ;  Q5PB34, SURE_ANAMM ;  B4UE89, SURE_ANASK ;
DR   Q3MB98, SURE_ANAVT ;  O67004, SURE_AQUAE ;  A8EX03, SURE_ARCB4 ;
DR   O29320, SURE_ARCFU ;  Q5P832, SURE_AROAE ;  A8I066, SURE_AZOC5 ;
DR   A1K4E9, SURE_AZOSB ;  C1DSR8, SURE_AZOVD ;  Q5LHD7, SURE_BACFN ;
DR   Q64YA5, SURE_BACFR ;  Q8A0L8, SURE_BACTN ;  A6L1M6, SURE_BACV8 ;
DR   B2IJG0, SURE_BEII9 ;  Q2L006, SURE_BORA1 ;  Q7WI36, SURE_BORBR ;
DR   Q7W670, SURE_BORPA ;  A9IP06, SURE_BORPD ;  Q7VXN2, SURE_BORPE ;
DR   Q89L02, SURE_BRAJA ;  A5EJV7, SURE_BRASB ;  A4YV68, SURE_BRASO ;
DR   C0ZGV3, SURE_BREBN ;  B2S5B9, SURE_BRUA1 ;  Q2YNM5, SURE_BRUA2 ;
DR   Q57DM1, SURE_BRUAB ;  A9MAQ9, SURE_BRUC2 ;  C0RIL9, SURE_BRUMB ;
DR   P66879, SURE_BRUME ;  A5VQ63, SURE_BRUO2 ;  B0CLL1, SURE_BRUSI ;
DR   P66880, SURE_BRUSU ;  A3MK87, SURE_BURM7 ;  A2S290, SURE_BURM9 ;
DR   Q62JV2, SURE_BURMA ;  A1V4L3, SURE_BURMS ;  A3NVY2, SURE_BURP0 ;
DR   Q3JRP0, SURE_BURP1 ;  A3NA65, SURE_BURP6 ;  Q63UU4, SURE_BURPS ;
DR   Q2SWF5, SURE_BURTA ;  A4JEQ1, SURE_BURVG ;  Q13Z72, SURE_BURXL ;
DR   A8MBQ3, SURE_CALMQ ;  A7ZCD9, SURE_CAMC1 ;  A7H0A1, SURE_CAMC5 ;
DR   A0RMU4, SURE_CAMFF ;  A7I2X3, SURE_CAMHC ;  A8FK82, SURE_CAMJ8 ;
DR   A7H578, SURE_CAMJD ;  Q9PIK6, SURE_CAMJE ;  A1VY14, SURE_CAMJJ ;
DR   Q5HWH7, SURE_CAMJR ;  B9KDQ8, SURE_CAMLR ;  Q3ADI0, SURE_CARHZ ;
DR   B8GX52, SURE_CAUCN ;  Q9A6T5, SURE_CAUCR ;  B0T1Q2, SURE_CAUSK ;
DR   Q5L5X3, SURE_CHLAB ;  B8G513, SURE_CHLAD ;  Q3ATV8, SURE_CHLCH ;
DR   Q254M8, SURE_CHLFF ;  B3EFW1, SURE_CHLL2 ;  Q9PKH4, SURE_CHLMU ;
DR   A1BI19, SURE_CHLPD ;  Q9Z8S6, SURE_CHLPN ;  B0B9W8, SURE_CHLT2 ;
DR   Q3KME4, SURE_CHLTA ;  B0BBJ8, SURE_CHLTB ;  Q8KC69, SURE_CHLTE ;
DR   O84220, SURE_CHLTR ;  Q1QU76, SURE_CHRSD ;  Q7NRV1, SURE_CHRVO ;
DR   A8ANV8, SURE_CITK8 ;  A7FQP3, SURE_CLOB1 ;  C3KZ52, SURE_CLOB6 ;
DR   A6LS61, SURE_CLOB8 ;  B2UXL6, SURE_CLOBA ;  B2TPM3, SURE_CLOBB ;
DR   A5HYC6, SURE_CLOBH ;  C1FQW9, SURE_CLOBJ ;  B1IDC2, SURE_CLOBK ;
DR   A7G9Y6, SURE_CLOBL ;  B1KTK1, SURE_CLOBM ;  B9E0C7, SURE_CLOK1 ;
DR   A5N6V8, SURE_CLOK5 ;  Q899M5, SURE_CLOTE ;  Q487E6, SURE_COLP3 ;
DR   B6J4X6, SURE_COXB1 ;  B6J3X6, SURE_COXB2 ;  A9KDH9, SURE_COXBN ;
DR   A9N9U7, SURE_COXBR ;  Q9KI21, SURE_COXBU ;  Q0K950, SURE_CUPNH ;
DR   Q46ZH1, SURE_CUPPJ ;  B3R1L4, SURE_CUPTR ;  B1WXT3, SURE_CYAA5 ;
DR   B8HSQ9, SURE_CYAP4 ;  B7KB74, SURE_CYAP7 ;  Q11WK5, SURE_CYTH3 ;
DR   Q47D24, SURE_DECAR ;  Q3Z8C0, SURE_DEHE1 ;  A5FR64, SURE_DEHSB ;
DR   Q3ZXG5, SURE_DEHSC ;  Q1J2E1, SURE_DEIGD ;  Q9RRT8, SURE_DEIRA ;
DR   B8FC91, SURE_DESAA ;  C6BUG4, SURE_DESAD ;  B1I3V7, SURE_DESAP ;
DR   B8J2G2, SURE_DESDA ;  Q30YV9, SURE_DESDG ;  B8FYS8, SURE_DESHD ;
DR   Q24WI0, SURE_DESHY ;  C4XNX3, SURE_DESMR ;  A8ZXL1, SURE_DESOH ;
DR   A4J5D2, SURE_DESRM ;  Q72A55, SURE_DESVH ;  B8DN39, SURE_DESVM ;
DR   A1VCE4, SURE_DESVV ;  A5EY39, SURE_DICNV ;  A8LQK5, SURE_DINSH ;
DR   A7ZQI8, SURE_ECO24 ;  B7UHG3, SURE_ECO27 ;  B7MKL8, SURE_ECO45 ;
DR   B7LEG2, SURE_ECO55 ;  P0A842, SURE_ECO57 ;  B5Z3A6, SURE_ECO5E ;
DR   B7NT88, SURE_ECO7I ;  B7MZ45, SURE_ECO81 ;  B7LXF6, SURE_ECO8A ;
DR   C4ZZP8, SURE_ECOBW ;  B1XCS0, SURE_ECODH ;  A8A3M3, SURE_ECOHS ;
DR   A1AET8, SURE_ECOK1 ;  Q0TEB4, SURE_ECOL5 ;  P0A841, SURE_ECOL6 ;
DR   B1IUT5, SURE_ECOLC ;  P0A840, SURE_ECOLI ;  B7N6X4, SURE_ECOLU ;
DR   B6I6D4, SURE_ECOSE ;  Q1R7U7, SURE_ECOUT ;  C5BGI8, SURE_EDWI9 ;
DR   Q3YSH3, SURE_EHRCJ ;  Q2GG44, SURE_EHRCR ;  Q5FHG1, SURE_EHRRG ;
DR   Q5HBM5, SURE_EHRRW ;  A4WDU9, SURE_ENT38 ;  A7MJ60, SURE_ENTS8 ;
DR   B2VG26, SURE_ERWT9 ;  Q2NDM8, SURE_ERYLH ;  B7LWJ1, SURE_ESCF3 ;
DR   A7HLM0, SURE_FERNB ;  A5FK02, SURE_FLAJ1 ;  A6H213, SURE_FLAPJ ;
DR   C1A8T7, SURE_GEMAT ;  B5EHF5, SURE_GEOBB ;  Q39VS1, SURE_GEOMG ;
DR   B9M4Z4, SURE_GEOSF ;  Q74CZ6, SURE_GEOSL ;  C6E582, SURE_GEOSM ;
DR   A5G4S8, SURE_GEOUR ;  Q7NNG7, SURE_GLOVI ;  A0M5L6, SURE_GRAFK ;
DR   Q7VN28, SURE_HAEDU ;  Q4QML8, SURE_HAEI8 ;  A5UE24, SURE_HAEIE ;
DR   A5UHI7, SURE_HAEIG ;  P45681, SURE_HAEIN ;  Q0I5H7, SURE_HAES1 ;
DR   B0URR1, SURE_HAES2 ;  P36686, SURE_HAESO ;  Q2SKW4, SURE_HAHCH ;
DR   A1WWY6, SURE_HALHL ;  Q5V4L7, SURE_HALMA ;  B8CWH0, SURE_HALOH ;
DR   B0R567, SURE_HALS3 ;  Q9HQB2, SURE_HALSA ;  Q18F17, SURE_HALWD ;
DR   Q17WX7, SURE_HELAH ;  Q7VJA8, SURE_HELHP ;  B0TAY4, SURE_HELMI ;
DR   B6JMF1, SURE_HELP2 ;  B5Z7T4, SURE_HELPG ;  Q1CSU4, SURE_HELPH ;
DR   Q9ZKS0, SURE_HELPJ ;  B2UU78, SURE_HELPS ;  O25584, SURE_HELPY ;
DR   A9B1D4, SURE_HERA2 ;  A4G4J2, SURE_HERAR ;  A2BLQ8, SURE_HYPBU ;
DR   Q0C0W3, SURE_HYPNA ;  Q5QUC6, SURE_IDILO ;  A6SZY0, SURE_JANMA ;
DR   Q28TH7, SURE_JANSC ;  B5XV37, SURE_KLEP3 ;  C5CG17, SURE_KOSOT ;
DR   C1DBF4, SURE_LARHH ;  Q1MQB1, SURE_LAWIP ;  Q5X5S5, SURE_LEGPA ;
DR   A5IBD5, SURE_LEGPC ;  Q9S4T3, SURE_LEGPH ;  Q5WX53, SURE_LEGPL ;
DR   B0SBG1, SURE_LEPBA ;  Q04Q98, SURE_LEPBJ ;  Q054Q4, SURE_LEPBL ;
DR   B0SJM4, SURE_LEPBP ;  B1Y0T1, SURE_LEPCP ;  Q72MU5, SURE_LEPIC ;
DR   Q8EZH9, SURE_LEPIN ;  Q2W4A1, SURE_MAGSA ;  A0L4K6, SURE_MAGSM ;
DR   Q65Q81, SURE_MANSM ;  A1TZ53, SURE_MARAV ;  Q0ANE1, SURE_MARMM ;
DR   A6VUV4, SURE_MARMS ;  Q11HC9, SURE_MESSB ;  Q8TUG3, SURE_METAC ;
DR   A7I6S6, SURE_METB6 ;  Q46D82, SURE_METBF ;  Q12U23, SURE_METBU ;
DR   B7KPY4, SURE_METC4 ;  Q604W8, SURE_METCA ;  A9VY48, SURE_METEP ;
DR   Q1H096, SURE_METFK ;  Q2FLE8, SURE_METHJ ;  Q57979, SURE_METJA ;
DR   Q8TY72, SURE_METKA ;  A2SQ45, SURE_METLZ ;  A4FXC7, SURE_METM5 ;
DR   A9AAP6, SURE_METM6 ;  A6VFZ9, SURE_METM7 ;  Q8PX31, SURE_METMA ;
DR   A3CVB4, SURE_METMJ ;  Q6LYE0, SURE_METMP ;  B8IN19, SURE_METNO ;
DR   B1ZJ09, SURE_METPB ;  A2SF75, SURE_METPP ;  B1LXR9, SURE_METRJ ;
DR   A5UMJ5, SURE_METS3 ;  B0UD11, SURE_METS4 ;  B8ERC6, SURE_METSB ;
DR   Q2NI97, SURE_METST ;  O27484, SURE_METTH ;  A0B8M6, SURE_METTP ;
DR   A6UP61, SURE_METVS ;  B0JX00, SURE_MICAN ;  Q2RJD1, SURE_MOOTA ;
DR   Q1D402, SURE_MYXXD ;  Q3INV7, SURE_NATPD ;  B2A4J5, SURE_NATTJ ;
DR   Q5F7V9, SURE_NEIG1 ;  B4RKR4, SURE_NEIG2 ;  A9M0S4, SURE_NEIM0 ;
DR   Q9JTP0, SURE_NEIMA ;  Q9JYP8, SURE_NEIMB ;  A1KUT0, SURE_NEIMF ;
DR   Q0ADP1, SURE_NITEC ;  Q82VV9, SURE_NITEU ;  Q1QME1, SURE_NITHX ;
DR   Q2YBR8, SURE_NITMU ;  Q3JCZ4, SURE_NITOC ;  A6Q4L7, SURE_NITSB ;
DR   Q3SRQ5, SURE_NITWN ;  Q8YMT3, SURE_NOSS1 ;  A6X1F1, SURE_OCHA4 ;
DR   B6JFP2, SURE_OLICO ;  A6LF90, SURE_PARD8 ;  A1B5M1, SURE_PARDP ;
DR   A7HXK5, SURE_PARL1 ;  Q6MCW1, SURE_PARUW ;  P57955, SURE_PASMU ;
DR   Q3A4N5, SURE_PELCD ;  Q3B5Y2, SURE_PELLD ;  A1ASL7, SURE_PELPD ;
DR   A5D2G6, SURE_PELTS ;  A9BER9, SURE_PETMO ;  B4RDI0, SURE_PHEZH ;
DR   Q7N8K4, SURE_PHOLL ;  Q6LMT6, SURE_PHOPR ;  Q6KZ11, SURE_PICTO ;
DR   A1VQF4, SURE_POLNA ;  Q128R7, SURE_POLSJ ;  A4SYE9, SURE_POLSQ ;
DR   B2RH81, SURE_PORG3 ;  Q7MT32, SURE_PORGI ;  A3PEA4, SURE_PROM0 ;
DR   A2C436, SURE_PROM1 ;  A8G678, SURE_PROM2 ;  A2CB17, SURE_PROM3 ;
DR   A9BBN4, SURE_PROM4 ;  A2BXX8, SURE_PROM5 ;  Q319M0, SURE_PROM9 ;
DR   Q7VAV8, SURE_PROMA ;  B4F224, SURE_PROMH ;  Q7V8I0, SURE_PROMM ;
DR   Q7V0I6, SURE_PROMP ;  A2BSJ2, SURE_PROMS ;  Q46JK0, SURE_PROMT ;
DR   A4SD83, SURE_PROVI ;  Q48F87, SURE_PSE14 ;  Q15P28, SURE_PSEA6 ;
DR   A6V1G3, SURE_PSEA7 ;  B7V8C4, SURE_PSEA8 ;  Q02R97, SURE_PSEAB ;
DR   Q9HY05, SURE_PSEAE ;  Q1I654, SURE_PSEE4 ;  Q4KHE8, SURE_PSEF5 ;
DR   C3K705, SURE_PSEFS ;  Q3IDD3, SURE_PSEHT ;  A4XWR2, SURE_PSEMY ;
DR   A5W821, SURE_PSEP1 ;  Q3KH84, SURE_PSEPF ;  B0KSC7, SURE_PSEPG ;
DR   Q88MF1, SURE_PSEPK ;  B1JB30, SURE_PSEPW ;  Q886L5, SURE_PSESM ;
DR   Q4ZWQ0, SURE_PSEU2 ;  A4VJV2, SURE_PSEU5 ;  Q1QD10, SURE_PSYCK ;
DR   A1SSR3, SURE_PSYIN ;  A4WJK1, SURE_PYRAR ;  Q5JE78, SURE_PYRKO ;
DR   B2U9T8, SURE_RALPJ ;  Q8Y040, SURE_RALSO ;  B3PXU4, SURE_RHIE6 ;
DR   Q2K966, SURE_RHIEC ;  Q1MHM1, SURE_RHIL3 ;  Q98LC9, SURE_RHILO ;
DR   B5ZMG1, SURE_RHILW ;  O08248, SURE_RHIME ;  C3MBU3, SURE_RHISN ;
DR   Q7UKT6, SURE_RHOBA ;  Q21UQ9, SURE_RHOFD ;  Q2IWG9, SURE_RHOP2 ;
DR   Q07N44, SURE_RHOP5 ;  Q6N5X7, SURE_RHOPA ;  Q214W6, SURE_RHOPB ;
DR   Q136H7, SURE_RHOPS ;  B3Q6H7, SURE_RHOPT ;  Q2RTH6, SURE_RHORT ;
DR   A3PIZ9, SURE_RHOS1 ;  Q3J3D0, SURE_RHOS4 ;  A4WU04, SURE_RHOS5 ;
DR   B9KQZ2, SURE_RHOSK ;  Q163U3, SURE_ROSDO ;  Q9JP92, SURE_RUBGE ;
DR   Q1ATN8, SURE_RUBXD ;  A1AXG6, SURE_RUTMC ;  A9MF31, SURE_SALAR ;
DR   Q57KJ7, SURE_SALCH ;  B5QW15, SURE_SALEP ;  B5RDQ0, SURE_SALG2 ;
DR   B4T454, SURE_SALNS ;  Q5PEG4, SURE_SALPA ;  A9N2D0, SURE_SALPB ;
DR   B5BEY1, SURE_SALPK ;  Q2S1H7, SURE_SALRD ;  B4TTV8, SURE_SALSV ;
DR   P66882, SURE_SALTI ;  P66881, SURE_SALTY ;  A8G9Z5, SURE_SERP5 ;
DR   A1S4E2, SURE_SHEAM ;  B8E8T6, SURE_SHEB2 ;  A3D790, SURE_SHEB5 ;
DR   A6WR23, SURE_SHEB8 ;  A9KYG5, SURE_SHEB9 ;  Q12PY9, SURE_SHEDO ;
DR   Q086A5, SURE_SHEFN ;  B0TK09, SURE_SHEHH ;  A3QC82, SURE_SHELP ;
DR   Q8EBR5, SURE_SHEON ;  A8H1T0, SURE_SHEPA ;  A4Y938, SURE_SHEPC ;
DR   A0KU87, SURE_SHESA ;  A8FST3, SURE_SHESH ;  Q0HL67, SURE_SHESM ;
DR   Q0HXG5, SURE_SHESR ;  A1RHF8, SURE_SHESW ;  B1KPT1, SURE_SHEWM ;
DR   B2TZI7, SURE_SHIB3 ;  Q31XA6, SURE_SHIBS ;  Q32CI6, SURE_SHIDS ;
DR   Q0T1H5, SURE_SHIF8 ;  Q83JY2, SURE_SHIFL ;  Q3YYB8, SURE_SHISS ;
DR   Q5LQ08, SURE_SILPO ;  Q1GFP2, SURE_SILST ;  A6U8N9, SURE_SINMW ;
DR   Q2NVM2, SURE_SODGM ;  A9GFF6, SURE_SORC5 ;  A5V3Z0, SURE_SPHWW ;
DR   B4SR92, SURE_STRM5 ;  B2FK94, SURE_STRMK ;  Q30QB8, SURE_SULDN ;
DR   A6Q9V0, SURE_SULNB ;  B2VA83, SURE_SULSY ;  Q67NP4, SURE_SYMTH ;
DR   Q2LUH7, SURE_SYNAS ;  Q31LH6, SURE_SYNE7 ;  A0LHG0, SURE_SYNFM ;
DR   Q2JVR3, SURE_SYNJA ;  B1XPE2, SURE_SYNP2 ;  Q5N0F0, SURE_SYNP6 ;
DR   A5GMH4, SURE_SYNPW ;  Q7U5U4, SURE_SYNPX ;  A5GUT4, SURE_SYNR3 ;
DR   Q0IC13, SURE_SYNS3 ;  Q3AVE5, SURE_SYNS9 ;  Q3AL65, SURE_SYNSC ;
DR   Q0AXU4, SURE_SYNWW ;  P74709, SURE_SYNY3 ;  B7IH68, SURE_THEAB ;
DR   Q8DI06, SURE_THEEB ;  C5A6M8, SURE_THEGJ ;  A8F523, SURE_THELT ;
DR   A6LL96, SURE_THEM4 ;  P96112, SURE_THEMA ;  B9K7G8, SURE_THENN ;
DR   A5ILS0, SURE_THEP1 ;  B0K9J0, SURE_THEP3 ;  A1RYX4, SURE_THEPD ;
DR   B0K177, SURE_THEPX ;  B1LB13, SURE_THESQ ;  Q53W92, SURE_THET8 ;
DR   Q8RA90, SURE_THETN ;  Q31G71, SURE_THICR ;  Q3SKJ3, SURE_THIDA ;
DR   B8GRG3, SURE_THISH ;  C4LBQ6, SURE_TOLAT ;  O83434, SURE_TREPA ;
DR   Q10YV3, SURE_TRIEI ;  Q0W2Q3, SURE_UNCMA ;  C5CUL9, SURE_VARPS ;
DR   A1WE26, SURE_VEREI ;  A5CVV1, SURE_VESOH ;  A5F9D9, SURE_VIBC3 ;
DR   Q9KUI9, SURE_VIBCH ;  C3LS21, SURE_VIBCM ;  Q5E331, SURE_VIBF1 ;
DR   A7MTT7, SURE_VIBHB ;  Q87LQ5, SURE_VIBPA ;  Q8DC57, SURE_VIBVU ;
DR   Q7MHQ7, SURE_VIBVY ;  Q8D2P7, SURE_WIGBR ;  Q73G84, SURE_WOLPM ;
DR   B3CLR5, SURE_WOLPP ;  Q7M8G1, SURE_WOLSU ;  Q5GS87, SURE_WOLTR ;
DR   C0R4G7, SURE_WOLWR ;  Q8PLR4, SURE_XANAC ;  Q3BUS4, SURE_XANC5 ;
DR   Q4UTP8, SURE_XANC8 ;  B0RTZ9, SURE_XANCB ;  Q8P9Y7, SURE_XANCP ;
DR   Q2P1L4, SURE_XANOM ;  B2SUB2, SURE_XANOP ;  Q5GYL1, SURE_XANOR ;
DR   B2I8X7, SURE_XYLF2 ;  Q9PF20, SURE_XYLFA ;  B0U4U5, SURE_XYLFM ;
DR   Q87AK6, SURE_XYLFT ;  A1JJT7, SURE_YERE8 ;  A7FLX5, SURE_YERP3 ;
DR   Q1C475, SURE_YERPA ;  B2K580, SURE_YERPB ;  Q8ZBP9, SURE_YERPE ;
DR   A9R116, SURE_YERPG ;  Q1CLR3, SURE_YERPN ;  A4TQ00, SURE_YERPP ;
DR   Q66EC0, SURE_YERPS ;  B1JJF5, SURE_YERPY ;  Q5NNV1, SURE_ZYMMO ;
DR   P07024, USHA_ECOLI ;  Q9RN37, USHA_SALPU ;  Q56878, USHA_YERE8 ;
DR   P73440, Y1459_SYNY3;  Q8YSE9, Y3139_NOSS1;  Q8XCV3, YFBR_ECO57 ;
DR   Q8FFJ5, YFBR_ECOL6 ;  P76491, YFBR_ECOLI ;  P0A8Y2, YJJG_ECO57 ;
DR   P0A8Y1, YJJG_ECOLI ;
//
ID   3.1.3.6
DE   3'-nucleotidase.
CA   A 3'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.
CC   -!- Wide specificity for 3'-nucleotides.
DR   P08331, CPDB_ECOLI ;  P44764, CPDB_HAEIN ;  P26265, CPDB_SALTY ;
DR   P53052, CPDB_YEREN ;  O34313, NTPES_BACSU;  P24504, NUP3_PENSQ ;
DR   A8ANV8, SURE_CITK8 ;  A7ZQI8, SURE_ECO24 ;  B7UHG3, SURE_ECO27 ;
DR   B7MKL8, SURE_ECO45 ;  B7LEG2, SURE_ECO55 ;  P0A842, SURE_ECO57 ;
DR   B5Z3A6, SURE_ECO5E ;  B7NT88, SURE_ECO7I ;  B7MZ45, SURE_ECO81 ;
DR   B7LXF6, SURE_ECO8A ;  C4ZZP8, SURE_ECOBW ;  B1XCS0, SURE_ECODH ;
DR   A8A3M3, SURE_ECOHS ;  A1AET8, SURE_ECOK1 ;  Q0TEB4, SURE_ECOL5 ;
DR   P0A841, SURE_ECOL6 ;  B1IUT5, SURE_ECOLC ;  P0A840, SURE_ECOLI ;
DR   B7N6X4, SURE_ECOLU ;  B6I6D4, SURE_ECOSE ;  Q1R7U7, SURE_ECOUT ;
DR   C5BGI8, SURE_EDWI9 ;  A4WDU9, SURE_ENT38 ;  A7MJ60, SURE_ENTS8 ;
DR   B2VG26, SURE_ERWT9 ;  B7LWJ1, SURE_ESCF3 ;  B5XV37, SURE_KLEP3 ;
DR   Q7N8K4, SURE_PHOLL ;  B4F224, SURE_PROMH ;  A9MF31, SURE_SALAR ;
DR   Q57KJ7, SURE_SALCH ;  B5QW15, SURE_SALEP ;  B5RDQ0, SURE_SALG2 ;
DR   B4T454, SURE_SALNS ;  Q5PEG4, SURE_SALPA ;  A9N2D0, SURE_SALPB ;
DR   B5BEY1, SURE_SALPK ;  B4TTV8, SURE_SALSV ;  P66882, SURE_SALTI ;
DR   P66881, SURE_SALTY ;  A8G9Z5, SURE_SERP5 ;  B2TZI7, SURE_SHIB3 ;
DR   Q31XA6, SURE_SHIBS ;  Q32CI6, SURE_SHIDS ;  Q0T1H5, SURE_SHIF8 ;
DR   Q83JY2, SURE_SHIFL ;  Q3YYB8, SURE_SHISS ;  Q2NVM2, SURE_SODGM ;
DR   Q8D2P7, SURE_WIGBR ;  A1JJT7, SURE_YERE8 ;  A7FLX5, SURE_YERP3 ;
DR   Q1C475, SURE_YERPA ;  B2K580, SURE_YERPB ;  Q8ZBP9, SURE_YERPE ;
DR   A9R116, SURE_YERPG ;  Q1CLR3, SURE_YERPN ;  A4TQ00, SURE_YERPP ;
DR   Q66EC0, SURE_YERPS ;  B1JJF5, SURE_YERPY ;
//
ID   3.1.3.7
DE   3'(2'),5'-bisphosphate nucleotidase.
AN   3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase.
AN   3'-phosphoadenylylsulfate 3'-phosphatase.
AN   DPNPase.
AN   Phosphoadenylate 3'-nucleotidase.
CA   Adenosine 3',5'-bisphosphate + H(2)O = adenosine 5'-phosphate +
CA   phosphate.
CC   -!- Also acts on 3'-phosphoadenylylsulfate, and on the corresponding
CC       2'-phosphates.
DR   Q3ZCK3, BPNT1_BOVIN;  Q869K3, BPNT1_DICDI;  O95861, BPNT1_HUMAN;
DR   Q9Z0S1, BPNT1_MOUSE;  Q9Z1N4, BPNT1_RAT  ;  P70714, CYSQ_AGGAC ;
DR   P57624, CYSQ_BUCAI ;  Q8XCG6, CYSQ_ECO57 ;  Q8FAG5, CYSQ_ECOL6 ;
DR   P22255, CYSQ_ECOLI ;  P44332, CYSQ_HAEIN ;  P65164, CYSQ_MYCBO ;
DR   P46726, CYSQ_MYCLE ;  P65163, CYSQ_MYCTU ;  Q8Z153, CYSQ_SALTI ;
DR   P26264, CYSQ_SALTY ;  P59735, CYSQ_SHIFL ;  Q42546, DPNP1_ARATH;
DR   O49623, DPNP2_ARATH;  Q8GY63, DPNP3_ARATH;  Q84VY5, DPNP4_ARATH;
DR   Q38945, DPNPH_ARATH;  Q9M0Y6, DPNPM_ARATH;  Q55F34, DPNP_DICDI ;
DR   Q5BCG1, DPNP_EMENI ;  P0C5A3, DPNP_ORYSA ;  Q2QWT4, DPNP_ORYSJ ;
DR   O94505, DPNP_SCHPO ;  P46594, HAL21_CANAL;  Q59XQ1, HAL22_CANAL;
DR   P32179, MET22_YEAST;  O34600, NRNA_BACSU ;
//
ID   3.1.3.8
DE   3-phytase.
AN   1-phytase.
AN   Myo-inositol-hexakisphosphate 3-phosphohydrolase.
AN   Phytase.
AN   Phytate 1-phosphatase.
AN   Phytate 3-phosphatase.
AN   Phytate 6-phosphatase.
CA   Myo-inositol hexakisphosphate + H(2)O = 1D-myo-inositol 1,2,4,5,6-
CA   pentakisphosphate + phosphate.
PR   PROSITE; PDOC00538;
DR   O00085, PHYA1_ASPTE;  O00100, PHYA2_ASPTE;  P34753, PHYA_ASPAW ;
DR   O00092, PHYA_ASPFU ;  P34752, PHYA_ASPNG ;  Q9C1T1, PHYA_ASPOR ;
DR   Q0CLV1, PHYA_ASPTN ;  O00107, PHYA_THIHE ;  P34755, PHYB_ASPAW ;
DR   P81440, PHYB_ASPFI ;  P34754, PHYB_ASPNG ;  O00093, PHYB_EMENI ;
DR   O31097, PHYC_BACSU ;  O66037, PHYT_BACSD ;  P42094, PHYT_BACSU ;
//
ID   3.1.3.9
DE   Glucose-6-phosphatase.
CA   D-glucose 6-phosphate + H(2)O = D-glucose + phosphate.
CC   -!- Wide distribution in animal tissues.
CC   -!- Also catalyzes potent transphosphorylations from carbamoyl phosphate,
CC       hexose phosphates, diphosphate, phosphoenolpyruvate and nucleoside
CC       di- and triphosphates, to D-glucose, D-mannose, 3-methyl-D-glucose,
CC       or 2-deoxy-D-glucose (cf. EC 2.7.1.62, EC 2.7.1.79, and EC 3.9.1.1).
DR   Q9NQR9, G6PC2_HUMAN;  Q9Z186, G6PC2_MOUSE;  Q148G2, G6PC3_BOVIN;
DR   A1A5Z0, G6PC3_DANRE;  Q9BUM1, G6PC3_HUMAN;  Q6NSQ9, G6PC3_MOUSE;
DR   Q6AZ83, G6PC3_RAT  ;  Q29RU6, G6PC_BOVIN ;  O19133, G6PC_CANFA ;
DR   Q19KA1, G6PC_FELCA ;  O42153, G6PC_HAPNU ;  O42154, G6PC_HAPXE ;
DR   P35575, G6PC_HUMAN ;  P35576, G6PC_MOUSE ;  P43428, G6PC_RAT   ;
//
ID   3.1.3.10
DE   Glucose-1-phosphatase.
CA   Alpha-D-glucose 1-phosphate + H(2)O = D-glucose + phosphate.
CC   -!- Also acts, more slowly, on alpha-D-galactose 1-phosphate.
PR   PROSITE; PDOC00538;
DR   P19926, AGP_ECOLI  ;  Q52309, AGP_PRORE  ;  O33921, AGP_SALTY  ;
//
ID   3.1.3.11
DE   Fructose-bisphosphatase.
AN   Fructose 1,6-bisphosphatase.
AN   Hexose diphosphatase.
CA   D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate.
CC   -!- The animal enzyme also acts on sedoheptulose 1,7-bisphosphate.
PR   PROSITE; PDOC00114;
DR   P65164, CYSQ_MYCBO ;  P46726, CYSQ_MYCLE ;  P65163, CYSQ_MYCTU ;
DR   B0CAD9, F16A1_ACAM1;  A5E987, F16A1_BRASB;  B2JEJ7, F16A1_BURP8;
DR   Q13V64, F16A1_BURXL;  Q0KCY0, F16A1_CUPNH;  B3R3R6, F16A1_CUPTR;
DR   Q47A13, F16A1_DECAR;  A0M0J2, F16A1_GRAFK;  Q5V3Z1, F16A1_HALMA;
DR   B1XZ11, F16A1_LEPCP;  A2SFV4, F16A1_METPP;  Q1QH19, F16A1_NITHX;
DR   A1VL56, F16A1_POLNA;  Q3IFQ5, F16A1_PSEHT;  Q1LQ15, F16A1_RALME;
DR   Q21YM7, F16A1_RHOFD;  A3PNY0, F16A1_RHOS1;  Q3IYB9, F16A1_RHOS4;
DR   A4WW38, F16A1_RHOS5;  P27994, F16A1_RHOSH;  Q2S2I3, F16A1_SALRD;
DR   A7IGL7, F16A1_XANP2;  B0C7G7, F16A2_ACAM1;  A5EQ67, F16A2_BRASB;
DR   B2JVN8, F16A2_BURP8;  Q13QU8, F16A2_BURXL;  P19911, F16A2_CUPNH;
DR   B3RBL3, F16A2_CUPTR;  Q479X4, F16A2_DECAR;  A0M764, F16A2_GRAFK;
DR   Q5V311, F16A2_HALMA;  B1Y5W3, F16A2_LEPCP;  A2SJJ0, F16A2_METPP;
DR   Q1QGD7, F16A2_NITHX;  A1VNR3, F16A2_POLNA;  Q3IH61, F16A2_PSEHT;
DR   Q1LN82, F16A2_RALME;  Q21UY4, F16A2_RHOFD;  A3PRW1, F16A2_RHOS1;
DR   Q3IX60, F16A2_RHOS4;  A4WZQ4, F16A2_RHOS5;  P22780, F16A2_RHOSH;
DR   Q2S1G3, F16A2_SALRD;  A7IL64, F16A2_XANP2;  B2JX47, F16A3_BURP8;
DR   P19912, F16A3_CUPNH;  A2SJK3, F16A3_METPP;  Q3ICJ5, F16A3_PSEHT;
DR   A6LW95, F16C1_CLOB8;  A6M220, F16C2_CLOB8;  P25851, F16P1_ARATH;
DR   Q3SZB7, F16P1_BOVIN;  Q07204, F16P1_BRANA;  P09467, F16P1_HUMAN;
DR   Q9QXD6, F16P1_MOUSE;  O64422, F16P1_ORYSJ;  P46275, F16P1_PEA  ;
DR   P00636, F16P1_PIG  ;  P00637, F16P1_RABIT;  P19112, F16P1_RAT  ;
DR   P09199, F16P1_SHEEP;  Q42796, F16P1_SOYBN;  P22418, F16P1_SPIOL;
DR   P09195, F16P1_WHEAT;  Q9MA79, F16P2_ARATH;  Q42649, F16P2_BETVU;
DR   Q2KJJ9, F16P2_BOVIN;  P46267, F16P2_BRANA;  O00757, F16P2_HUMAN;
DR   P70695, F16P2_MOUSE;  Q9XF47, F16P2_MUSAC;  Q9SDL8, F16P2_ORYCO;
DR   A2WXB2, F16P2_ORYSI;  Q0JHF8, F16P2_ORYSJ;  Q8RW99, F16P2_PEA  ;
DR   Q9N0J6, F16P2_RABIT;  Q9Z1N1, F16P2_RAT  ;  Q43139, F16P2_SACHY;
DR   P46276, F16P2_SOLTU;  P14766, F16P2_SPIOL;  P97323, F16P3_MOUSE;
DR   A1TN89, F16PA_ACIAC;  Q6F982, F16PA_ACIAD;  B2HWU2, F16PA_ACIBC;
DR   B0VT80, F16PA_ACIBS;  A3M7W9, F16PA_ACIBT;  B0VDK0, F16PA_ACIBY;
DR   A5FWQ8, F16PA_ACICJ;  B5ELA6, F16PA_ACIF5;  A1W9H6, F16PA_ACISJ;
DR   A3N298, F16PA_ACTP2;  B3H282, F16PA_ACTP7;  B0BQZ1, F16PA_ACTPJ;
DR   A6VN92, F16PA_ACTSZ;  A0KJT2, F16PA_AERHH;  A4SM33, F16PA_AERS4;
DR   Q0A5B1, F16PA_ALHEH;  B6EPV3, F16PA_ALISL;  B4S2E8, F16PA_ALTMD;
DR   B3ERE1, F16PA_AMOA5;  Q3MCI4, F16PA_ANAVT;  A8EU55, F16PA_ARCB4;
DR   Q5P7F8, F16PA_AROAE;  A8I541, F16PA_AZOC5;  A1K430, F16PA_AZOSB;
DR   C1DHU3, F16PA_AZOVD;  Q2KZ46, F16PA_BORA1;  Q7WL20, F16PA_BORBR;
DR   Q7W7N2, F16PA_BORPA;  A9IQQ8, F16PA_BORPD;  Q7VZM9, F16PA_BORPE;
DR   Q8GKS1, F16PA_BRAJA;  A4YNQ7, F16PA_BRASO;  B2SAG4, F16PA_BRUA1;
DR   Q2YIQ9, F16PA_BRUA2;  Q578Z3, F16PA_BRUAB;  A9MCF4, F16PA_BRUC2;
DR   C0RM19, F16PA_BRUMB;  Q8YCV6, F16PA_BRUME;  A5VVE8, F16PA_BRUO2;
DR   A9WZF8, F16PA_BRUSI;  Q8FVG9, F16PA_BRUSU;  B1YUZ7, F16PA_BURA4;
DR   Q1BY59, F16PA_BURCA;  B1JXN8, F16PA_BURCC;  A0K5J0, F16PA_BURCH;
DR   B4EB94, F16PA_BURCJ;  Q0BHD7, F16PA_BURCM;  A9AEN5, F16PA_BURM1;
DR   A3MHJ7, F16PA_BURM7;  A2S4W0, F16PA_BURM9;  Q62LZ0, F16PA_BURMA;
DR   A1V6R5, F16PA_BURMS;  A3NY10, F16PA_BURP0;  Q3JPU4, F16PA_BURP1;
DR   A3NC72, F16PA_BURP6;  B2T699, F16PA_BURPP;  Q63RX4, F16PA_BURPS;
DR   Q39IJ4, F16PA_BURS3;  Q2SY57, F16PA_BURTA;  A4JCE2, F16PA_BURVG;
DR   A7ZCB2, F16PA_CAMC1;  A7GXH6, F16PA_CAMC5;  A0RP36, F16PA_CAMFF;
DR   A7I1B8, F16PA_CAMHC;  A8FLP9, F16PA_CAMJ8;  A7H3L9, F16PA_CAMJD;
DR   Q0PA50, F16PA_CAMJE;  A1VZI4, F16PA_CAMJJ;  Q5HUV6, F16PA_CAMJR;
DR   Q9A8G9, F16PA_CAUCR;  B0T0R1, F16PA_CAUSK;  B3PGC8, F16PA_CELJU;
DR   Q3AT00, F16PA_CHLCH;  B3EGL2, F16PA_CHLL2;  B3QQ73, F16PA_CHLP8;
DR   B3ELC6, F16PA_CHLPB;  A1BEB4, F16PA_CHLPD;  B3QWF5, F16PA_CHLT3;
DR   Q8KFG8, F16PA_CHLTE;  Q7NVB6, F16PA_CHRVO;  A8AMG4, F16PA_CITK8;
DR   Q47VB1, F16PA_COLP3;  Q46YH7, F16PA_CUPPJ;  B1WX40, F16PA_CYAA5;
DR   Q11R22, F16PA_CYTH3;  A9BW85, F16PA_DELAS;  C6BTU7, F16PA_DESAD;
DR   Q30ZN0, F16PA_DESDG;  Q72AZ9, F16PA_DESVH;  A1VD23, F16PA_DESVV;
DR   A5EVS5, F16PA_DICNV;  A7ZVB0, F16PA_ECO24;  Q8XCF0, F16PA_ECO57;
DR   B5Z3I7, F16PA_ECO5E;  B1XEL4, F16PA_ECODH;  A8A7Y7, F16PA_ECOHS;
DR   A1AJD7, F16PA_ECOK1;  Q0T9F7, F16PA_ECOL5;  P0A994, F16PA_ECOL6;
DR   B1ISX3, F16PA_ECOLC;  P0A993, F16PA_ECOLI;  B1LRB5, F16PA_ECOSM;
DR   Q1R324, F16PA_ECOUT;  A4W5X6, F16PA_ENT38;  A7MM48, F16PA_ENTS8;
DR   Q6D074, F16PA_ERWCT;  B2VCY1, F16PA_ERWT9;  A5FMJ5, F16PA_FLAJ1;
DR   A6GWD9, F16PA_FLAPJ;  B5EFV5, F16PA_GEOBB;  B3E2M3, F16PA_GEOLS;
DR   Q39UC4, F16PA_GEOMG;  Q74CM2, F16PA_GEOSL;  A5G439, F16PA_GEOUR;
DR   Q7NGN9, F16PA_GLOVI;  Q7VN74, F16PA_HAEDU;  Q4QL80, F16PA_HAEI8;
DR   A5UCP1, F16PA_HAEIE;  P45292, F16PA_HAEIN;  Q0I4Y5, F16PA_HAES1;
DR   B0USR6, F16PA_HAES2;  Q2S8D3, F16PA_HAHCH;  A1WZH0, F16PA_HALHL;
DR   B0R3Y1, F16PA_HALS3;  Q9HRI1, F16PA_HALSA;  Q18J03, F16PA_HALWD;
DR   Q17V54, F16PA_HELAH;  Q7VGH7, F16PA_HELHP;  B5Z9G5, F16PA_HELPG;
DR   Q1CR72, F16PA_HELPH;  Q9ZJ74, F16PA_HELPJ;  B2UVU9, F16PA_HELPS;
DR   O25936, F16PA_HELPY;  A4G2P0, F16PA_HERAR;  A2RQ29, F16PA_HERSE;
DR   Q5QVR9, F16PA_IDILO;  A6SVE7, F16PA_JANMA;  B5Y2X3, F16PA_KLEP3;
DR   A6THE3, F16PA_KLEP7;  Q1MRF1, F16PA_LAWIP;  B0SHG0, F16PA_LEPBA;
DR   Q04T19, F16PA_LEPBJ;  Q051E1, F16PA_LEPBL;  B0SQL1, F16PA_LEPBP;
DR   Q72RN8, F16PA_LEPIC;  Q8F421, F16PA_LEPIN;  Q2W3W0, F16PA_MAGSA;
DR   Q65S38, F16PA_MANSM;  A6W2V5, F16PA_MARMS;  A7I8R6, F16PA_METB6;
DR   B7L270, F16PA_METC4;  A9W1C8, F16PA_METEP;  Q1H3T1, F16PA_METFK;
DR   Q2FM20, F16PA_METHJ;  B3DWS5, F16PA_METI4;  A2ST39, F16PA_METLZ;
DR   B1Z939, F16PA_METPB;  B1LUU9, F16PA_METRJ;  B0UEK2, F16PA_METS4;
DR   B0JH56, F16PA_MICAN;  Q3ISJ9, F16PA_NATPD;  Q5F8C3, F16PA_NEIG1;
DR   B4RLD4, F16PA_NEIG2;  A9LYX9, F16PA_NEIM0;  A1IRQ3, F16PA_NEIMA;
DR   Q9JZH1, F16PA_NEIMB;  A1KTU6, F16PA_NEIMF;  Q0AGV1, F16PA_NITEC;
DR   Q82WY3, F16PA_NITEU;  Q3JF33, F16PA_NITOC;  A6Q349, F16PA_NITSB;
DR   P37099, F16PA_NITVU;  Q3SP44, F16PA_NITWN;  P48847, F16PA_NOSP7;
DR   P48991, F16PA_NOSS1;  A6X307, F16PA_OCHA4;  A1B2P8, F16PA_PARDP;
DR   A7HYA5, F16PA_PARL1;  Q9CMA4, F16PA_PASMU;  Q3A5T0, F16PA_PELCD;
DR   Q3B5N2, F16PA_PELLD;  B4SDN7, F16PA_PELPB;  A1APW8, F16PA_PELPD;
DR   C0QTP7, F16PA_PERMH;  Q7MYW6, F16PA_PHOLL;  Q6LV59, F16PA_PHOPR;
DR   B1XVF7, F16PA_POLNS;  Q12D67, F16PA_POLSJ;  A4SWM3, F16PA_POLSQ;
DR   B4S3F3, F16PA_PROA2;  B4F298, F16PA_PROMH;  A4SDH2, F16PA_PROVI;
DR   Q48PL3, F16PA_PSE14;  Q15ZB4, F16PA_PSEA6;  A6VDM7, F16PA_PSEA7;
DR   B7V3K3, F16PA_PSEA8;  Q02EQ6, F16PA_PSEAB;  Q9HU73, F16PA_PSEAE;
DR   Q1I3Q0, F16PA_PSEE4;  Q4KJP6, F16PA_PSEF5;  C3K7D6, F16PA_PSEFS;
DR   Q9LBE7, F16PA_PSEHY;  A4XPL2, F16PA_PSEMY;  A5WA74, F16PA_PSEP1;
DR   Q3KJG0, F16PA_PSEPF;  B0KM65, F16PA_PSEPG;  Q88CY9, F16PA_PSEPK;
DR   B1J2P7, F16PA_PSEPW;  Q87UX4, F16PA_PSESM;  Q4ZZI0, F16PA_PSEU2;
DR   A4VGC9, F16PA_PSEU5;  Q4FUA6, F16PA_PSYA2;  Q1QDE0, F16PA_PSYCK;
DR   A1T0H3, F16PA_PSYIN;  A5WGK6, F16PA_PSYWF;  B2U8C4, F16PA_RALPJ;
DR   Q8XXI7, F16PA_RALSO;  Q9EXV4, F16PA_RHIME;  O34011, F16PA_RHOCB;
DR   Q2J1K3, F16PA_RHOP2;  Q07N65, F16PA_RHOP5;  Q6N0W5, F16PA_RHOPA;
DR   Q213I9, F16PA_RHOPB;  Q13CA1, F16PA_RHOPS;  B3QB72, F16PA_RHOPT;
DR   Q2RRP2, F16PA_RHORT;  Q21L89, F16PA_SACD2;  B5F3E2, F16PA_SALA4;
DR   A9MEY3, F16PA_SALAR;  Q57GG7, F16PA_SALCH;  B5FSC7, F16PA_SALDC;
DR   B5R0U4, F16PA_SALEP;  B5R9H4, F16PA_SALG2;  B4TFG0, F16PA_SALHS;
DR   B4T3H9, F16PA_SALNS;  Q5PJ74, F16PA_SALPA;  A9N548, F16PA_SALPB;
DR   B5BKN5, F16PA_SALPK;  B4TT57, F16PA_SALSV;  Q8Z146, F16PA_SALTI;
DR   Q8ZK67, F16PA_SALTY;  A8G8Y2, F16PA_SERP5;  A1S351, F16PA_SHEAM;
DR   A3D0P6, F16PA_SHEB5;  A6WSQ6, F16PA_SHEB8;  A9L375, F16PA_SHEB9;
DR   Q12JW2, F16PA_SHEDO;  Q088C3, F16PA_SHEFN;  B0TTL6, F16PA_SHEHH;
DR   A3QAZ7, F16PA_SHELP;  Q8EAB6, F16PA_SHEON;  A8H0H1, F16PA_SHEPA;
DR   A4Y373, F16PA_SHEPC;  A0KSW7, F16PA_SHESA;  A8FRF1, F16PA_SHESH;
DR   Q0HMI8, F16PA_SHESM;  Q0HRA0, F16PA_SHESR;  A1RNR2, F16PA_SHESW;
DR   B1KEL4, F16PA_SHEWM;  B2TZ12, F16PA_SHIB3;  Q31TG8, F16PA_SHIBS;
DR   Q328V4, F16PA_SHIDS;  Q0SXH4, F16PA_SHIF8;  P0A995, F16PA_SHIFL;
DR   Q3YUB9, F16PA_SHISS;  P56886, F16PA_SINMW;  Q2NW44, F16PA_SODGM;
DR   A9G6T8, F16PA_SORC5;  B4SR24, F16PA_STRM5;  B2FU10, F16PA_STRMK;
DR   Q30RP0, F16PA_SULDN;  A6Q9C9, F16PA_SULNB;  B2V6E2, F16PA_SULSY;
DR   Q2LUC0, F16PA_SYNAS;  Q59943, F16PA_SYNE7;  Q2JTX5, F16PA_SYNJA;
DR   Q2JK61, F16PA_SYNJB;  B1XNG1, F16PA_SYNP2;  Q5N163, F16PA_SYNP6;
DR   P74324, F16PA_SYNY3;  C5BMI0, F16PA_TERTT;  Q8DLF2, F16PA_THEEB;
DR   Q31FI6, F16PA_THICR;  Q3SFS6, F16PA_THIDA;  Q118F5, F16PA_TRIEI;
DR   A1WH14, F16PA_VEREI;  A5F599, F16PA_VIBC3;  Q9KP35, F16PA_VIBCH;
DR   C3LRK7, F16PA_VIBCM;  Q5E887, F16PA_VIBF1;  B5FGE3, F16PA_VIBFM;
DR   A7MWE4, F16PA_VIBHB;  Q87SW0, F16PA_VIBPA;  B7VKW7, F16PA_VIBSL;
DR   Q8DE90, F16PA_VIBVU;  Q7MPD0, F16PA_VIBVY;  Q8D275, F16PA_WIGBR;
DR   Q7MAI9, F16PA_WOLSU;  Q8PR42, F16PA_XANAC;  Q3BZI4, F16PA_XANC5;
DR   Q4V0I4, F16PA_XANC8;  B0RLK6, F16PA_XANCB;  Q8PE85, F16PA_XANCP;
DR   P23014, F16PA_XANFL;  Q2P9K6, F16PA_XANOM;  B2SUX7, F16PA_XANOP;
DR   Q5H701, F16PA_XANOR;  A1JIU6, F16PA_YERE8;  A7FMU7, F16PA_YERP3;
DR   Q1CBY3, F16PA_YERPA;  B2K2N1, F16PA_YERPB;  Q0WBC9, F16PA_YERPE;
DR   A9R579, F16PA_YERPG;  Q1CEI9, F16PA_YERPN;  A4TRK7, F16PA_YERPP;
DR   Q66F84, F16PA_YERPS;  B1JMK6, F16PA_YERPY;  A6TLX6, F16PC_ALKMQ;
DR   A7ZAK3, F16PC_BACA2;  Q5LE70, F16PC_BACFN;  Q64VB2, F16PC_BACFR;
DR   Q45597, F16PC_BACSU;  Q8A8D9, F16PC_BACTN;  A6L4C6, F16PC_BACV8;
DR   Q97IR8, F16PC_CLOAB;  A7FRC9, F16PC_CLOB1;  C3L0R6, F16PC_CLOB6;
DR   B2V5F2, F16PC_CLOBA;  B2TNB5, F16PC_CLOBB;  A5HZ60, F16PC_CLOBH;
DR   C1FSJ4, F16PC_CLOBJ;  B1IF28, F16PC_CLOBK;  A7GAS1, F16PC_CLOBL;
DR   B1KVJ4, F16PC_CLOBM;  Q18B55, F16PC_CLOD6;  A0PYZ1, F16PC_CLONN;
DR   Q897W7, F16PC_CLOTE;  Q6AMN0, F16PC_DESPS;  Q834X4, F16PC_ENTFA;
DR   B0S0K3, F16PC_FINM2;  Q8RFB5, F16PC_FUSNN;  Q036S2, F16PC_LACC3;
DR   B3W9A8, F16PC_LACCB;  Q9CIU9, F16PC_LACLA;  A2RHX9, F16PC_LACLM;
DR   Q1WQZ0, F16PC_LACS1;  Q38UP9, F16PC_LACSS;  Q92DI8, F16PC_LISIN;
DR   C1L199, F16PC_LISMC;  Q721Y7, F16PC_LISMF;  Q8Y8R5, F16PC_LISMO;
DR   A0AGV7, F16PC_LISW6;  Q8EMI3, F16PC_OCEIH;  A6LI52, F16PC_PARD8;
DR   Q03HS1, F16PC_PEDPA;  B2RIZ0, F16PC_PORG3;  Q7MW52, F16PC_PORGI;
DR   Q21FJ6, F16PC_SACD2;  A9FZA0, F16PC_SORC5;  A7X6K5, F16PC_STAA1;
DR   A6U4P6, F16PC_STAA2;  Q2FDY9, F16PC_STAA3;  Q2FVB2, F16PC_STAA8;
DR   A5IVU3, F16PC_STAA9;  Q2YW94, F16PC_STAAB;  Q5HD37, F16PC_STAAC;
DR   A6QK04, F16PC_STAAE;  Q99RB9, F16PC_STAAM;  Q7A3I5, F16PC_STAAN;
DR   Q6GDS9, F16PC_STAAR;  Q6G6F9, F16PC_STAAS;  A8Z3B1, F16PC_STAAT;
DR   Q8NUT7, F16PC_STAAW;  Q5HLB1, F16PC_STAEQ;  Q8CN27, F16PC_STAES;
DR   Q4L907, F16PC_STAHJ;  Q4A071, F16PC_STAS1;  A0SJA5, F16PC_STAXY;
DR   Q3K2F6, F16PC_STRA1;  Q8E6K1, F16PC_STRA3;  Q8E146, F16PC_STRA5;
DR   A8AWF2, F16PC_STRGC;  A3CMR5, F16PC_STRSV;  B9DRN4, F16PC_STRU0;
DR   Q6RYT0, F16P_DICDI ;  Q05079, F16P_KLULA ;  P09202, F16P_SCHPO ;
DR   P09201, F16P_YEAST ;  B0C1Z3, FBSB1_ACAM1;  B0BZF8, FBSB2_ACAM1;
DR   Q3M6T3, FBSB_ANAVT ;  B1WQ07, FBSB_CYAA5 ;  Q7NG31, FBSB_GLOVI ;
DR   B0JKN5, FBSB_MICAN ;  Q8YY12, FBSB_NOSS1 ;  A3PCH5, FBSB_PROM0 ;
DR   A2C1K3, FBSB_PROM1 ;  A8G4E5, FBSB_PROM2 ;  A2CAB7, FBSB_PROM3 ;
DR   A2BW64, FBSB_PROM5 ;  Q31BB0, FBSB_PROM9 ;  Q7TVA4, FBSB_PROMA ;
DR   Q7V808, FBSB_PROMM ;  Q7V1T8, FBSB_PROMP ;  A2BQQ2, FBSB_PROMS ;
DR   Q46LG3, FBSB_PROMT ;  Q31QY2, FBSB_SYNE7 ;  Q2JWU7, FBSB_SYNJA ;
DR   Q2JJG9, FBSB_SYNJB ;  B1XLK5, FBSB_SYNP2 ;  Q5N3B5, FBSB_SYNP6 ;
DR   Q7U770, FBSB_SYNPX ;  A5GTE9, FBSB_SYNR3 ;  Q0I9I3, FBSB_SYNS3 ;
DR   Q3AXK3, FBSB_SYNS9 ;  Q3AK74, FBSB_SYNSC ;  P73922, FBSB_SYNY3 ;
DR   Q8DJE9, FBSB_THEEB ;  Q117I5, FBSB_TRIEI ;  P21437, GLPX2_ECOLI;
DR   Q03224, GLPX_BACSU ;  Q6M6E7, GLPX_CORGL ;  P0A9D0, GLPX_ECOL6 ;
DR   P0A9C9, GLPX_ECOLI ;  P44811, GLPX_HAEIN ;  Q7U0N5, GLPX_MYCBO ;
DR   A1KHN9, GLPX_MYCBP ;  C1AM93, GLPX_MYCBT ;  B8ZSG6, GLPX_MYCLB ;
DR   Q9CBH9, GLPX_MYCLE ;  A5U1E6, GLPX_MYCTA ;  A5WLC4, GLPX_MYCTF ;
DR   C6DV63, GLPX_MYCTK ;  O53447, GLPX_MYCTU ;  P0A9D1, GLPX_SHIFL ;
//
ID   3.1.3.12
DE   Trehalose-phosphatase.
AN   Trehalose 6-phosphate phosphatase.
CA   Trehalose 6-phosphate + H(2)O = trehalose + phosphate.
DR   A8NS89, GOB1_BRUMA ;  A8X485, GOB1_CAEBR ;  Q9XTQ5, GOB1_CAEEL ;
DR   P31678, OTSB_ECOLI ;  A0QKN5, OTSB_MYCA1 ;  Q7TWL7, OTSB_MYCBO ;
DR   A1KP65, OTSB_MYCBP ;  Q49734, OTSB_MYCLE ;  B2HDP8, OTSB_MYCMM ;
DR   Q73U90, OTSB_MYCPA ;  A5U846, OTSB_MYCTA ;  O50401, OTSB_MYCTU ;
DR   A0PMI0, OTSB_MYCUA ;  P55611, OTSB_RHISN ;  E1WGG9, OTSB_SALTS ;
DR   P0CL50, OTSB_SALTY ;  P78875, TPP1_SCHPO ;  Q8SSL0, TPP_ENCCU  ;
DR   O14145, TPS2_SCHPO ;  P31688, TPS2_YEAST ;
//
ID   3.1.3.13
DE   Bisphosphoglycerate phosphatase.
CA   2,3-bisphospho-D-glycerate + H(2)O = 3-phospho-D-glycerate + phosphate.
PR   PROSITE; PDOC00158;
DR   Q3SZ62, PGAM1_BOVIN;  Q5ZLN1, PGAM1_CHICK;  P18669, PGAM1_HUMAN;
DR   Q9DBJ1, PGAM1_MOUSE;  Q5RFB8, PGAM1_PONAB;  P25113, PGAM1_RAT  ;
DR   Q32KV0, PGAM2_BOVIN;  P15259, PGAM2_HUMAN;  O70250, PGAM2_MOUSE;
DR   P16290, PGAM2_RAT  ;  Q8N0Y7, PGAM4_HUMAN;  Q8MKE8, PGAM4_PANTR;
DR   Q54NE6, PGAM_DICDI ;  Q3T014, PMGE_BOVIN ;  P07738, PMGE_HUMAN ;
DR   Q4R6L7, PMGE_MACFA ;  P15327, PMGE_MOUSE ;  P07952, PMGE_RABIT ;
//
ID   3.1.3.14
DE   Methylphosphothioglycerate phosphatase.
CA   S-methyl-3-phospho-1-thio-D-glycerate + H(2)O = S-methyl-1-thio-D-
CA   glycerate + phosphate.
//
ID   3.1.3.15
DE   Histidinol-phosphatase.
CA   L-histidinol phosphate + H(2)O = L-histidinol + phosphate.
DR   A3N3W1, HIS7_ACTP2 ;  B3GZG9, HIS7_ACTP7 ;  B0BU51, HIS7_ACTPJ ;
DR   A6VM11, HIS7_ACTSZ ;  Q5LB00, HIS7_BACFN ;  Q64RE9, HIS7_BACFR ;
DR   Q8ABA7, HIS7_BACTN ;  Q1LT69, HIS7_BAUCH ;  Q7VQW8, HIS7_BLOFL ;
DR   B8D8Q4, HIS7_BUCA5 ;  P57203, HIS7_BUCAI ;  Q9ZHE4, HIS7_BUCAP ;
DR   B8D708, HIS7_BUCAT ;  P59454, HIS7_BUCBP ;  A8FNR1, HIS7_CAMJ8 ;
DR   A7H5U9, HIS7_CAMJD ;  Q9PM76, HIS7_CAMJE ;  A1W1K1, HIS7_CAMJJ ;
DR   Q5HSJ2, HIS7_CAMJR ;  Q47XB6, HIS7_COLP3 ;  Q9S5G5, HIS7_ECO57 ;
DR   Q8FG50, HIS7_ECOL6 ;  P06987, HIS7_ECOLI ;  Q6D409, HIS7_ERWCT ;
DR   Q4QN72, HIS7_HAEI8 ;  A5UA18, HIS7_HAEIE ;  A5UGY3, HIS7_HAEIG ;
DR   P44327, HIS7_HAEIN ;  A6TBC5, HIS7_KLEP7 ;  Q5X5X1, HIS7_LEGPA ;
DR   Q5ZW89, HIS7_LEGPH ;  Q5WX93, HIS7_LEGPL ;  Q65RB3, HIS7_MANSM ;
DR   P57920, HIS7_PASMU ;  Q7N6I2, HIS7_PHOLL ;  P62455, HIS7_PHOPR ;
DR   Q15RU7, HIS7_PSEA6 ;  Q5PDP5, HIS7_SALPA ;  Q8Z5J8, HIS7_SALTI ;
DR   P10368, HIS7_SALTY ;  Q8EFB3, HIS7_SHEON ;  Q83R05, HIS7_SHIFL ;
DR   Q2NTX3, HIS7_SODGM ;  B4STN9, HIS7_STRM5 ;  B2FPM1, HIS7_STRMK ;
DR   Q9KSX1, HIS7_VIBCH ;  Q87QK9, HIS7_VIBPA ;  Q8D8Q2, HIS7_VIBVU ;
DR   Q7MLS4, HIS7_VIBVY ;  P58881, HIS7_XANAC ;  Q3BUF5, HIS7_XANC5 ;
DR   Q4UU42, HIS7_XANC8 ;  B0RSL6, HIS7_XANCB ;  P58882, HIS7_XANCP ;
DR   Q2P3K1, HIS7_XANOM ;  B2SKN6, HIS7_XANOP ;  Q5H0K9, HIS7_XANOR ;
DR   B2I5X9, HIS7_XYLF2 ;  Q9PBC7, HIS7_XYLFA ;  B0U3B1, HIS7_XYLFM ;
DR   Q87C31, HIS7_XYLFT ;  Q8ZFX7, HIS7_YERPE ;  Q66C51, HIS7_YERPS ;
DR   Q9K801, HIS9_BACHD ;  O34411, HIS9_BACSU ;  P58291, HIS9_CLOAB ;
DR   Q9RX45, HIS9_DEIRA ;  Q02150, HIS9_LACLA ;  O14059, HIS9_SCHPO ;
DR   Q9WZR1, HIS9_THEMA ;  P38635, HIS9_YEAST ;  P56160, HISN_CHLP8 ;
DR   Q8NS80, HISN_CORGL ;  P95189, HISN_MYCTU ;  Q9K4B1, HISN_STRCO ;
DR   Q6NPM8, IMPL2_ARATH;
//
ID   3.1.3.16
DE   Phosphoprotein phosphatase.
AN   Protein phosphatase-1.
AN   Protein phosphatase-2A.
AN   Protein phosphatase-2B.
AN   Protein phosphatase-2C.
AN   Serine/threonine specific protein phosphatase.
CA   A phosphoprotein + H(2)O = a protein + phosphate.
CC   -!- A group of enzymes removing the serine- or threonine-bound phosphate
CC       group from a wide range of phosphoproteins, including a number of
CC       enzymes which have been phosphorylated under the action of a kinase
CC       (cf. EC 3.1.3.48).
CC   -!- The spleen enzyme also acts on phenolic phosphates and phosphamides
CC       (cf. EC 3.9.1.1).
PR   PROSITE; PDOC00115;
PR   PROSITE; PDOC00785;
PR   PROSITE; PDOC00792;
PR   PROSITE; PDOC50969;
DR   Q9C5U0, AHK4_ARATH ;  Q6J2K6, BIP2C_ORYSI;  Q10QL5, BIP2C_ORYSJ;
DR   Q8L7U5, BSL1_ARATH ;  Q60EX6, BSL1_ORYSJ ;  Q9SJF0, BSL2_ARATH ;
DR   Q2QM47, BSL2_ORYSJ ;  Q9SHS7, BSL3_ARATH ;  Q9LR78, BSU1_ARATH ;
DR   Q9UNH5, CC14A_HUMAN;  Q6GQT0, CC14A_MOUSE;  O60729, CC14B_HUMAN;
DR   Q6PFY9, CC14B_MOUSE;  A4D256, CC14C_HUMAN;  A6N3Q4, CC14C_HYLSY;
DR   Q16667, CDKN3_HUMAN;  Q810P3, CDKN3_MOUSE;  Q9MYN5, CDKN3_PIG  ;
DR   B2RZ50, CDKN3_RAT  ;  Q1RMV9, CNEP1_BOVIN;  Q61C05, CNEP1_CAEBR;
DR   Q20432, CNEP1_CAEEL;  Q9VRG7, CNEP1_DROME;  Q29I63, CNEP1_DROPS;
DR   O95476, CNEP1_HUMAN;  Q3TP92, CNEP1_MOUSE;  Q3B7T6, CNEP1_RAT  ;
DR   Q8JIL9, CNEP1_XENLA;  Q28HW9, CNEP1_XENTR;  Q5U395, CNEPA_DANRE;
DR   Q5U3T3, CNEPB_DANRE;  Q5YDB6, CPL1_ARATH ;  Q5YDB5, CPL2_ARATH ;
DR   Q8LL04, CPL3_ARATH ;  Q00IB6, CPL4_ARATH ;  Q9Y5B0, CTDP1_HUMAN;
DR   Q7TSG2, CTDP1_MOUSE;  Q9GZU7, CTDS1_HUMAN;  P58466, CTDS1_MOUSE;
DR   O14595, CTDS2_HUMAN;  Q8BX07, CTDS2_MOUSE;  Q9PTJ6, CTDSL_CHICK;
DR   O15194, CTDSL_HUMAN;  P58465, CTDSL_MOUSE;  Q9XYL0, CTDS_DICDI ;
DR   Q1LWL2, DS22A_DANRE;  Q566R7, DS22B_DANRE;  P0C598, DUPD1_ANOCA;
DR   P0C591, DUPD1_BOVIN;  P0C5A2, DUPD1_CALMI;  P0C597, DUPD1_CHICK;
DR   Q29RA3, DUPD1_DANRE;  P0C5A0, DUPD1_GASAC;  P0C592, DUPD1_HORSE;
DR   Q68J44, DUPD1_HUMAN;  P0C593, DUPD1_MONDO;  Q8BK84, DUPD1_MOUSE;
DR   P0C5A1, DUPD1_ORYLA;  P0C594, DUPD1_PANTR;  P0C596, DUPD1_PIG  ;
DR   P0C595, DUPD1_RAT  ;  P0C599, DUPD1_TAKRU;  Q4RQD3, DUPD1_TETNG;
DR   Q4KL92, DUPD1_XENLA;  A4IHU7, DUPD1_XENTR;  Q0IID7, DUS10_BOVIN;
DR   Q9Y6W6, DUS10_HUMAN;  Q9ESS0, DUS10_MOUSE;  Q9UNI6, DUS12_HUMAN;
DR   Q9D0T2, DUS12_MOUSE;  Q9JIM4, DUS12_RAT  ;  Q9UII6, DUS13_HUMAN;
DR   Q9QYJ7, DUS13_MOUSE;  Q17QM8, DUS14_BOVIN;  O95147, DUS14_HUMAN;
DR   Q9JLY7, DUS14_MOUSE;  Q9H1R2, DUS15_HUMAN;  Q8R4V2, DUS15_MOUSE;
DR   Q9BY84, DUS16_HUMAN;  Q5BIP9, DUS18_BOVIN;  Q8NEJ0, DUS18_HUMAN;
DR   Q8VE01, DUS18_MOUSE;  Q5R8X2, DUS18_PONAB;  Q6AXW7, DUS18_RAT  ;
DR   Q8WTR2, DUS19_HUMAN;  Q8K4T5, DUS19_MOUSE;  P28562, DUS1_HUMAN ;
DR   P28563, DUS1_MOUSE ;  Q64623, DUS1_RAT   ;  Q9H596, DUS21_HUMAN;
DR   Q9D9D8, DUS21_MOUSE;  Q9NRW4, DUS22_HUMAN;  Q99N11, DUS22_MOUSE;
DR   Q6GQJ8, DUS22_XENLA;  Q5XHB2, DUS22_XENTR;  Q9BVJ7, DUS23_HUMAN;
DR   Q6NT99, DUS23_MOUSE;  Q17QJ3, DUS26_BOVIN;  Q9BV47, DUS26_HUMAN;
DR   Q9D700, DUS26_MOUSE;  Q5R6H6, DUS26_PONAB;  Q5FVI9, DUS26_RAT  ;
DR   Q4G0W2, DUS28_HUMAN;  Q8BTR5, DUS28_MOUSE;  Q05923, DUS2_HUMAN ;
DR   Q05922, DUS2_MOUSE ;  P51452, DUS3_HUMAN ;  Q9D7X3, DUS3_MOUSE ;
DR   Q5RD73, DUS3_PONAB ;  Q9PW71, DUS4_CHICK ;  Q13115, DUS4_HUMAN ;
DR   Q8BFV3, DUS4_MOUSE ;  Q62767, DUS4_RAT   ;  Q16690, DUS5_HUMAN ;
DR   O54838, DUS5_RAT   ;  Q2KJ36, DUS6_BOVIN ;  Q16828, DUS6_HUMAN ;
DR   Q9DBB1, DUS6_MOUSE ;  Q64346, DUS6_RAT   ;  Q16829, DUS7_HUMAN ;
DR   Q91Z46, DUS7_MOUSE ;  Q63340, DUS7_RAT   ;  Q13202, DUS8_HUMAN ;
DR   O09112, DUS8_MOUSE ;  Q99956, DUS9_HUMAN ;  Q9VVW5, DUSK3_DROME;
DR   Q55E39, DUSP1_DICDI;  Q54R42, DUSP2_DICDI;  Q55BI8, DUSP3_DICDI;
DR   Q54T76, DUSP4_DICDI;  Q556Y8, DUSPR_DICDI;  Q1M199, EPM2A_CANFA;
DR   O95278, EPM2A_HUMAN;  Q9WUA5, EPM2A_MOUSE;  Q91XQ2, EPM2A_RAT  ;
DR   Q8SV03, FCP1_ENCCU ;  Q9P376, FCP1_SCHPO ;  Q03254, FCP1_YEAST ;
DR   P49594, FEM2_CAEEL ;  Q9SX52, FYPP1_ARATH;  Q9LHE7, FYPP3_ARATH;
DR   Q8LSN3, FYPP_PEA   ;  Q61JR3, GLC7A_CAEBR;  Q27497, GLC7A_CAEEL;
DR   Q627N3, GLC7B_CAEBR;  P48727, GLC7B_CAEEL;  Q0IIF0, ILKAP_BOVIN;
DR   Q9H0C8, ILKAP_HUMAN;  Q8R0F6, ILKAP_MOUSE;  Q9Z1Z6, ILKAP_RAT  ;
DR   Q6B8I1, MDSP_HUMAN ;  Q6B8I0, MDSP_MOUSE ;  Q55CS7, MPL1_DICDI ;
DR   Q55CS8, MPL2_DICDI ;  Q54Y32, MPL3_DICDI ;  O59718, NEM1_SCHPO ;
DR   P38757, NEM1_YEAST ;  Q9LR65, P2C01_ARATH;  Q942P9, P2C01_ORYSJ;
DR   Q8RX37, P2C02_ARATH;  Q9FYN7, P2C02_ORYSJ;  Q9LNW3, P2C03_ARATH;
DR   Q0JMD4, P2C03_ORYSJ;  Q9LQN6, P2C04_ARATH;  Q5JJY4, P2C04_ORYSJ;
DR   O80492, P2C05_ARATH;  Q5JKN1, P2C05_ORYSJ;  Q9SA22, P2C06_ARATH;
DR   Q0JLP9, P2C06_ORYSJ;  Q9LNP9, P2C07_ARATH;  Q0JL75, P2C07_ORYSJ;
DR   Q9LMT1, P2C08_ARATH;  Q5SN75, P2C08_ORYSJ;  Q9LME4, P2C09_ARATH;
DR   Q5N9N2, P2C09_ORYSJ;  Q9S9Z7, P2C10_ARATH;  Q67UX7, P2C10_ORYSJ;
DR   Q8VZN9, P2C11_ARATH;  Q6ETK3, P2C11_ORYSJ;  Q9FX08, P2C12_ARATH;
DR   Q6Z8B9, P2C12_ORYSJ;  Q9LNF4, P2C13_ARATH;  Q6EN45, P2C13_ORYSJ;
DR   Q9FXE4, P2C14_ARATH;  Q6K6N7, P2C14_ORYSJ;  Q9M9C6, P2C15_ARATH;
DR   Q6YTI2, P2C15_ORYSJ;  Q9CAJ0, P2C16_ARATH;  Q6K1U4, P2C16_ORYSJ;
DR   Q8L7I4, P2C17_ARATH;  Q6K1U0, P2C17_ORYSJ;  Q8RXZ4, P2C18_ARATH;
DR   A3A8Q4, P2C18_ORYSJ;  Q9SL76, P2C19_ARATH;  Q0DZT4, P2C19_ORYSJ;
DR   Q9SIU8, P2C20_ARATH;  Q6K5I0, P2C20_ORYSJ;  O81716, P2C21_ARATH;
DR   A3A8W2, P2C21_ORYSJ;  Q9SLA1, P2C22_ARATH;  A3A8W6, P2C22_ORYSJ;
DR   Q9ZV25, P2C23_ARATH;  Q6H7J4, P2C23_ORYSJ;  Q9ZW21, P2C24_ARATH;
DR   Q6H7J3, P2C24_ORYSJ;  O80871, P2C25_ARATH;  Q6ZHC8, P2C25_ORYSJ;
DR   O64730, P2C26_ARATH;  Q6ZGY0, P2C26_ORYSJ;  P93006, P2C27_ARATH;
DR   Q69QZ0, P2C27_ORYSJ;  O64583, P2C28_ARATH;  Q10S32, P2C28_ORYSJ;
DR   O82302, P2C29_ARATH;  Q8H063, P2C29_ORYSJ;  Q9XEE8, P2C30_ARATH;
DR   Q84JI0, P2C30_ORYSJ;  Q940A2, P2C31_ARATH;  Q10NB9, P2C31_ORYSJ;
DR   Q8RWN7, P2C32_ARATH;  Q10MX1, P2C32_ORYSJ;  Q9M8R7, P2C33_ARATH;
DR   Q10MN6, P2C33_ORYSJ;  Q9M9W9, P2C34_ARATH;  Q5MFV5, P2C34_ORYSI;
DR   Q94H98, P2C34_ORYSJ;  Q7XJ53, P2C35_ARATH;  Q84T94, P2C35_ORYSJ;
DR   Q9SR24, P2C36_ARATH;  Q7Y138, P2C36_ORYSJ;  P49598, P2C37_ARATH;
DR   Q7XP01, P2C37_ORYSJ;  Q9LHJ9, P2C38_ARATH;  Q7XW27, P2C38_ORYSJ;
DR   Q9LDA7, P2C39_ARATH;  Q7XVF9, P2C39_ORYSJ;  Q9LUS8, P2C40_ARATH;
DR   Q7XTC7, P2C40_ORYSJ;  Q9LRZ4, P2C41_ARATH;  Q7XQU7, P2C41_ORYSJ;
DR   Q0V7V2, P2C42_ARATH;  Q7XU84, P2C42_ORYSJ;  Q9LUU7, P2C43_ARATH;
DR   Q7XUC5, P2C43_ORYSJ;  Q0JAA0, P2C44_ORYSJ;  Q7XR06, P2C45_ORYSJ;
DR   Q9SD12, P2C46_ARATH;  A3AZ89, P2C46_ORYSJ;  Q9SD02, P2C47_ARATH;
DR   Q6AUQ4, P2C47_ORYSJ;  Q94CL8, P2C48_ARATH;  Q6L482, P2C48_ORYSJ;
DR   Q3EAF9, P2C49_ARATH;  Q65XG6, P2C49_ORYSJ;  Q9M1V8, P2C50_ARATH;
DR   Q6L5H6, P2C50_ORYSJ;  Q93YS2, P2C51_ARATH;  Q65XK7, P2C51_ORYSJ;
DR   Q8GY60, P2C52_ARATH;  Q6L5C4, P2C52_ORYSJ;  Q9SUF4, P2C53_ARATH;
DR   Q6L4R7, P2C53_ORYSJ;  Q9T010, P2C54_ARATH;  Q5SMK6, P2C54_ORYSJ;
DR   Q9SUK9, P2C55_ARATH;  Q652Z7, P2C55_ORYSJ;  P49597, P2C56_ARATH;
DR   Q0DBU3, P2C56_ORYSJ;  P49599, P2C57_ARATH;  Q69VD9, P2C57_ORYSJ;
DR   Q93YW5, P2C58_ARATH;  Q67UP9, P2C58_ORYSJ;  Q8RXV3, P2C59_ARATH;
DR   Q5Z6F5, P2C59_ORYSJ;  Q9SZ53, P2C60_ARATH;  Q5Z8P0, P2C60_ORYSJ;
DR   O82637, P2C61_ARATH;  Q7XHN8, P2C61_ORYSJ;  Q93V88, P2C62_ARATH;
DR   Q0D673, P2C62_ORYSJ;  O81760, P2C63_ARATH;  Q0D629, P2C63_ORYSJ;
DR   Q5PNS9, P2C64_ARATH;  Q8H4S6, P2C64_ORYSJ;  Q6NKS1, P2C65_ARATH;
DR   Q8H2T0, P2C65_ORYSJ;  Q9LZ86, P2C66_ARATH;  Q6ZKL8, P2C66_ORYSJ;
DR   Q501F9, P2C67_ARATH;  Q0J2R1, P2C67_ORYSJ;  Q84JD5, P2C68_ARATH;
DR   Q0J2L7, P2C68_ORYSJ;  Q8LAY8, P2C69_ARATH;  Q67J17, P2C69_ORYSJ;
DR   P46014, P2C70_ARATH;  Q653S3, P2C70_ORYSJ;  Q4PSE8, P2C71_ARATH;
DR   Q339D2, P2C71_ORYSJ;  Q9XGZ9, P2C72_ARATH;  Q7XCJ7, P2C72_ORYSJ;
DR   Q0WRB2, P2C73_ARATH;  Q2RBJ6, P2C73_ORYSJ;  Q9FG61, P2C74_ARATH;
DR   Q53Q11, P2C74_ORYSJ;  Q9FLI3, P2C75_ARATH;  Q2R637, P2C75_ORYSJ;
DR   Q94AT1, P2C76_ARATH;  A3CCP9, P2C76_ORYSJ;  O04719, P2C77_ARATH;
DR   Q2QWE3, P2C77_ORYSJ;  Q9FIF5, P2C78_ARATH;  Q2QN36, P2C78_ORYSJ;
DR   Q9FKX4, P2C79_ARATH;  Q9LVQ8, P2C80_ARATH;  Q61CA3, PGAM5_CAEBR;
DR   Q09422, PGAM5_CAEEL;  Q502L2, PGAM5_DANRE;  B3MR30, PGAM5_DROAN;
DR   B3P9N0, PGAM5_DROER;  B4JMM7, PGAM5_DROGR;  O46084, PGAM5_DROME;
DR   B4L6S9, PGAM5_DROMO;  B4GXS1, PGAM5_DROPE;  Q29HG0, PGAM5_DROPS;
DR   B4I9J6, PGAM5_DROSE;  B4R313, PGAM5_DROSI;  B4M7S0, PGAM5_DROVI;
DR   B4NE96, PGAM5_DROWI;  B4PY69, PGAM5_DROYA;  Q96HS1, PGAM5_HUMAN;
DR   Q8BX10, PGAM5_MOUSE;  Q562B5, PGAM5_RAT  ;  Q5FWM4, PGAM5_XENLA;
DR   Q6GL33, PGAM5_XENTR;  O60346, PHLP1_HUMAN;  Q8CHE4, PHLP1_MOUSE;
DR   Q9WTR8, PHLP1_RAT  ;  Q6ZVD8, PHLP2_HUMAN;  Q8BXA7, PHLP2_MOUSE;
DR   Q09564, PHLPP_CAEEL;  Q9VJ07, PHLPP_DROME;  P48480, PP11_ACECL ;
DR   P30366, PP11_ARATH ;  P48461, PP11_DROME ;  P13681, PP11_SCHPO ;
DR   O04856, PP11_TOBAC ;  P23733, PP11_TRYBB ;  P20604, PP11_YEAST ;
DR   P48481, PP12_ACECL ;  P48482, PP12_ARATH ;  P12982, PP12_DROME ;
DR   P23880, PP12_SCHPO ;  O04857, PP12_TOBAC ;  P23734, PP12_TRYBB ;
DR   P32598, PP12_YEAST ;  P48483, PP13_ARATH ;  Q05547, PP13_DROME ;
DR   O04858, PP13_TOBAC ;  P48484, PP14_ARATH ;  P48485, PP15_ARATH ;
DR   P48486, PP16_ARATH ;  O82733, PP17_ARATH ;  O82734, PP18_ARATH ;
DR   Q9M9W3, PP19_ARATH ;  Q3T0E7, PP1A_BOVIN ;  Q8WMS6, PP1A_CANFA ;
DR   P62136, PP1A_HUMAN ;  P62137, PP1A_MOUSE ;  P62139, PP1A_RABIT ;
DR   P62138, PP1A_RAT   ;  Q3SWW9, PP1B_BOVIN ;  Q8MJ47, PP1B_CANFA ;
DR   P62207, PP1B_CHICK ;  P48462, PP1B_DROME ;  P62140, PP1B_HUMAN ;
DR   P62141, PP1B_MOUSE ;  P61292, PP1B_PIG   ;  Q5R740, PP1B_PONAB ;
DR   P62143, PP1B_RABIT ;  P62142, PP1B_RAT   ;  Q6GQL2, PP1B_XENLA ;
DR   Q5I085, PP1B_XENTR ;  P36874, PP1GA_XENLA;  Q7SZ10, PP1GB_XENLA;
DR   P61287, PP1G_BOVIN ;  Q8MJ46, PP1G_CANFA ;  P36873, PP1G_HUMAN ;
DR   P63087, PP1G_MOUSE ;  P63088, PP1G_RAT   ;  Q8SRZ0, PP1L_ENCCU ;
DR   P23777, PP1_BRANA  ;  P48487, PP1_BRAOL  ;  O15757, PP1_DICDI  ;
DR   P20654, PP1_EMENI  ;  P22198, PP1_MAIZE  ;  P48488, PP1_MEDSV  ;
DR   Q9UW86, PP1_NEUCR  ;  P48489, PP1_ORYSJ  ;  P48490, PP1_PHAVU  ;
DR   Q07099, PP2A1_ARATH;  Q9HFQ2, PP2A1_EMENI;  P48580, PP2A1_NEUCR;
DR   A2YEB4, PP2A1_ORYSI;  Q0DBD3, PP2A1_ORYSJ;  P48726, PP2A1_PARTE;
DR   P23635, PP2A1_SCHPO;  P23594, PP2A1_YEAST;  Q07098, PP2A2_ARATH;
DR   Q8X178, PP2A2_ERYGR;  A2XN40, PP2A2_ORYSI;  Q10BT5, PP2A2_ORYSJ;
DR   A0CNL9, PP2A2_PARTE;  P23636, PP2A2_SCHPO;  P23595, PP2A2_YEAST;
DR   P48578, PP2A3_ARATH;  A2X2G3, PP2A3_ORYSI;  Q0E2S4, PP2A3_ORYSJ;
DR   Q6BFF6, PP2A3_PARTE;  Q07100, PP2A4_ARATH;  P0C5D7, PP2A4_ORYSI;
DR   A3C4N5, PP2A4_ORYSJ;  P32838, PP2A4_YEAST;  O04951, PP2A5_ARATH;
DR   O04860, PP2A5_TOBAC;  P67774, PP2AA_BOVIN;  P48463, PP2AA_CHICK;
DR   Q9XZE5, PP2AA_DICDI;  P67775, PP2AA_HUMAN;  P63330, PP2AA_MOUSE;
DR   P67776, PP2AA_PIG  ;  P67777, PP2AA_RABIT;  P63331, PP2AA_RAT  ;
DR   Q0P594, PP2AB_BOVIN;  Q54RD6, PP2AB_DICDI;  P62714, PP2AB_HUMAN;
DR   P62715, PP2AB_MOUSE;  P11493, PP2AB_PIG  ;  P11611, PP2AB_RABIT;
DR   P62716, PP2AB_RAT  ;  P48577, PP2A_ACECL ;  P23778, PP2A_BRANA ;
DR   P23696, PP2A_DROME ;  P48579, PP2A_HELAN ;  Q9ZSE4, PP2A_HEVBR ;
DR   Q06009, PP2A_MEDSA ;  Q9XGH7, PP2A_TOBAC ;  O42773, PP2B1_CRYNV;
DR   P48456, PP2B1_DROME;  P23287, PP2B1_YEAST;  Q27889, PP2B2_DROME;
DR   P14747, PP2B2_YEAST;  Q9VXF1, PP2B3_DROME;  P48452, PP2BA_BOVIN;
DR   Q7YSW8, PP2BA_DICDI;  Q08209, PP2BA_HUMAN;  P63328, PP2BA_MOUSE;
DR   P63329, PP2BA_RAT  ;  P16298, PP2BB_HUMAN;  P48453, PP2BB_MOUSE;
DR   P20651, PP2BB_RAT  ;  P48454, PP2BC_HUMAN;  P48455, PP2BC_MOUSE;
DR   Q4WUR1, PP2B_ASPFU ;  P48457, PP2B_EMENI ;  Q05681, PP2B_NEUCR ;
DR   Q12705, PP2B_SCHPO ;  P49595, PP2C1_CAEEL;  P49444, PP2C1_PARTE;
DR   P40371, PP2C1_SCHPO;  P35182, PP2C1_YEAST;  P49596, PP2C2_CAEEL;
DR   A0BLX0, PP2C2_PARTE;  Q09172, PP2C2_SCHPO;  P39966, PP2C2_YEAST;
DR   A0BQL0, PP2C3_PARTE;  Q09173, PP2C3_SCHPO;  P34221, PP2C3_YEAST;
DR   A0DTY1, PP2C4_PARTE;  O14156, PP2C4_SCHPO;  P38089, PP2C4_YEAST;
DR   A0CUB5, PP2C5_PARTE;  O14189, PP2C5_SCHPO;  Q12511, PP2C5_YEAST;
DR   A0DSB3, PP2C6_PARTE;  P25646, PP2C6_YEAST;  P38797, PP2C7_YEAST;
DR   P36982, PP2C_LEICH ;  Q5XAP6, PP2C_STRP6 ;  A8XE00, PP4C1_CAEBR;
DR   Q9XW79, PP4C1_CAEEL;  Q9XTT8, PP4C2_CAEEL;  A8WGP3, PP4CA_DANRE;
DR   A9JRC7, PP4CB_DANRE;  Q74ZR2, PP4C_ASHGO ;  A6H772, PP4C_BOVIN ;
DR   Q6FM81, PP4C_CANGA ;  Q9Y0B7, PP4C_DICDI ;  O76932, PP4C_DROME ;
DR   P60510, PP4C_HUMAN ;  Q6CNT6, PP4C_KLULA ;  P97470, PP4C_MOUSE ;
DR   Q5R6K8, PP4C_PONAB ;  P11084, PP4C_RABIT ;  Q5BJ92, PP4C_RAT   ;
DR   Q6IP91, PP4C_XENLA ;  Q6P861, PP4C_XENTR ;  P32345, PP4C_YEAST ;
DR   O14829, PPE1_HUMAN ;  O35655, PPE1_MOUSE ;  Q3SWT6, PPE1_RAT   ;
DR   P36614, PPE1_SCHPO ;  O14830, PPE2_HUMAN ;  O35385, PPE2_MOUSE ;
DR   Q09496, PPH6_CAEEL ;  P47354, PPH_MYCGE  ;  P75525, PPH_MYCPN  ;
DR   Q6NVU2, PPIG_XENTR ;  O62829, PPM1A_BOVIN;  P35813, PPM1A_HUMAN;
DR   P49443, PPM1A_MOUSE;  P35814, PPM1A_RABIT;  P20650, PPM1A_RAT  ;
DR   O62830, PPM1B_BOVIN;  O75688, PPM1B_HUMAN;  P36993, PPM1B_MOUSE;
DR   P35815, PPM1B_RAT  ;  O15297, PPM1D_HUMAN;  Q9QZ67, PPM1D_MOUSE;
DR   Q8WY54, PPM1E_HUMAN;  Q80TL0, PPM1E_MOUSE;  Q80Z30, PPM1E_RAT  ;
DR   P49593, PPM1F_HUMAN;  Q8CGA0, PPM1F_MOUSE;  Q9WVR7, PPM1F_RAT  ;
DR   P79126, PPM1G_BOVIN;  O15355, PPM1G_HUMAN;  Q4R4V2, PPM1G_MACFA;
DR   Q61074, PPM1G_MOUSE;  Q05AL2, PPM1H_DANRE;  Q9ULR3, PPM1H_HUMAN;
DR   Q3UYC0, PPM1H_MOUSE;  Q5M821, PPM1H_RAT  ;  Q28DF4, PPM1H_XENTR;
DR   Q5JR12, PPM1J_HUMAN;  Q149T7, PPM1J_MOUSE;  Q641Y6, PPM1J_RAT  ;
DR   Q2PC20, PPM1K_BOVIN;  Q8N3J5, PPM1K_HUMAN;  Q8BXN7, PPM1K_MOUSE;
DR   Q5R522, PPM1K_PONAB;  Q6ING9, PPM1K_XENLA;  A5PJZ2, PPM1L_BOVIN;
DR   Q5SGD2, PPM1L_HUMAN;  Q8BHN0, PPM1L_MOUSE;  Q96MI6, PPM1M_HUMAN;
DR   Q8BU27, PPM1M_MOUSE;  Q8N819, PPM1N_HUMAN;  Q8BGL1, PPM1N_MOUSE;
DR   Q84XU2, PPP5_ARATH ;  P53041, PPP5_HUMAN ;  Q60676, PPP5_MOUSE ;
DR   P55739, PPP5_RABIT ;  P53042, PPP5_RAT   ;  Q84K11, PPP5_SOLLC ;
DR   Q9U9A3, PPP6_DICDI ;  Q27884, PPP6_DROME ;  O00743, PPP6_HUMAN ;
DR   Q9CQR6, PPP6_MOUSE ;  Q64620, PPP6_RAT   ;  Q9LNG5, PPP7L_ARATH;
DR   Q9FN02, PPP7_ARATH ;  P32945, PPQ1_YEAST ;  P38148, PPS1_YEAST ;
DR   O43049, PPT1_SCHPO ;  P53043, PPT1_YEAST ;  Q5U3N5, PPTC7_DANRE;
DR   Q8NI37, PPTC7_HUMAN;  Q6NVE9, PPTC7_MOUSE;  Q6GR25, PPTC7_XENLA;
DR   P48529, PPX1_ARATH ;  P49576, PPX1_PARTE ;  P48528, PPX2_ARATH ;
DR   A0DJ90, PPX2_PARTE ;  A0C1E4, PPX3_PARTE ;  A0CCD2, PPX4_PARTE ;
DR   P11612, PPY_DROME  ;  P26570, PPZ1_YEAST ;  P33329, PPZ2_YEAST ;
DR   P78968, PPZ_SCHPO  ;  P03772, PP_LAMBD   ;  P55798, PRP1_ECOLI ;
DR   Q8ZNY9, PRP1_SALTY ;  P55799, PRP2_ECOLI ;  Q8ZMH3, PRP2_SALTY ;
DR   O34779, PRPC_BACSU ;  P71588, PSTP_MYCTU ;  B3MTI8, PTC71_DROAN;
DR   B3P5D3, PTC71_DROER;  B4JYN1, PTC71_DROGR;  Q9VAH4, PTC71_DROME;
DR   B4K616, PTC71_DROMO;  B4G653, PTC71_DROPE;  Q29AP0, PTC71_DROPS;
DR   B4HZE7, PTC71_DROSE;  B4R089, PTC71_DROSI;  B4M5T5, PTC71_DROVI;
DR   B4NBL6, PTC71_DROWI;  B4PPK3, PTC71_DROYA;  P60483, PTEN_CANFA ;
DR   Q8T9S7, PTEN_DICDI ;  P60484, PTEN_HUMAN ;  O08586, PTEN_MOUSE ;
DR   Q9PUT6, PTEN_XENLA ;  Q39491, PTP3_CHLMO ;  Q86BN8, PTPM1_DROME;
DR   Q8WUK0, PTPM1_HUMAN;  Q66GT5, PTPM1_MOUSE;  P0C089, PTPM1_RAT  ;
DR   P40421, RDGC_DROME ;  A6NK39, S72L1_HUMAN;  A8MSY0, S72L2_HUMAN;
DR   A6NG73, S72L3_HUMAN;  P49600, SP2E_BACME ;  P37475, SP2E_BACSU ;
DR   O15743, SPNA_DICDI ;  Q8WYL5, SSH1_HUMAN ;  Q76I79, SSH1_MOUSE ;
DR   Q76I76, SSH2_HUMAN ;  Q5SW75, SSH2_MOUSE ;  Q8TE77, SSH3_HUMAN ;
DR   Q8K330, SSH3_MOUSE ;  Q5XIS1, SSH3_RAT   ;  Q6NN85, SSH_DROME  ;
DR   Q6IVY4, SSH_XENLA  ;  Q75E60, SSU72_ASHGO;  Q4WHY5, SSU72_ASPFU;
DR   Q2UPU5, SSU72_ASPOR;  Q17QI2, SSU72_BOVIN;  Q6FMU7, SSU72_CANGA;
DR   Q2HFZ9, SSU72_CHAGB;  Q5ZJQ7, SSU72_CHICK;  P0CR77, SSU72_CRYNB;
DR   P0CR76, SSU72_CRYNJ;  Q6PC19, SSU72_DANRE;  Q6BYP7, SSU72_DEBHA;
DR   Q558Z3, SSU72_DICDI;  Q4IPC8, SSU72_GIBZE;  Q9NP77, SSU72_HUMAN;
DR   Q6CQ61, SSU72_KLULA;  Q9CY97, SSU72_MOUSE;  Q7SFY0, SSU72_NEUCR;
DR   Q4KLK9, SSU72_RAT  ;  O42868, SSU72_SCHPO;  Q6NRQ7, SSU72_XENLA;
DR   Q6C195, SSU72_YARLI;  P53538, SSU72_YEAST;  Q92AI7, STP1_LISIN ;
DR   Q71YJ5, STP1_LISMF ;  Q8Y678, STP1_LISMO ;  A0AJS6, STP1_LISW6 ;
DR   Q2KJD7, UBCP1_BOVIN;  Q5ZJJ8, UBCP1_CHICK;  Q6DI37, UBCP1_DANRE;
DR   Q8WVY7, UBCP1_HUMAN;  Q8BGR9, UBCP1_MOUSE;  Q5R4C4, UBCP1_PONAB;
DR   Q5FWT7, UBCP1_RAT  ;  Q641F1, UBCP1_XENLA;  Q28EX9, UBCP1_XENTR;
DR   Q8W3M6, UBCP_ARATH ;  P54092, VP2_CAV26  ;  P54093, VP2_CAV82  ;
DR   P69484, VP2_CAVC1  ;  Q9IZU7, VP2_CAVCA  ;  P69485, VP2_CAVCI  ;
DR   Q7K4Q5, Y0417_DROME;  Q54T01, Y2105_DICDI;  Q54WS9, Y9461_DICDI;
DR   Q10298, YD44_SCHPO ;  O74789, YOU5_SCHPO ;  P48459, YSD1_CAEEL ;
DR   P48458, YT91_CAEEL ;  P48460, YY06_CAEEL ;
//
ID   3.1.3.17
DE   [Phosphorylase] phosphatase.
CA   [Phosphorylase a] + 4 H(2)O = 2 [phosphorylase b] + 4 phosphate.
//
ID   3.1.3.18
DE   Phosphoglycolate phosphatase.
CA   2-phosphoglycolate + H(2)O = glycolate + phosphate.
DR   Q9S586, GPH1_PSEAE ;  Q9HZ62, GPH2_PSEAE ;  P40852, GPHC_CUPNH ;
DR   P40853, GPHP_CUPNH ;  Q8UEY9, GPH_AGRT5  ;  O67359, GPH_AQUAE  ;
DR   Q9A5Z2, GPH_CAUCR  ;  Q7NW10, GPH_CHRVO  ;  Q48A85, GPH_COLP3  ;
DR   P58422, GPH_ECO57  ;  Q8FCW0, GPH_ECOL6  ;  P32662, GPH_ECOLI  ;
DR   Q9EYY5, GPH_ENTAE  ;  Q6CZR3, GPH_ERWCT  ;  Q4QMY0, GPH_HAEI8  ;
DR   P44755, GPH_HAEIN  ;  Q65Q22, GPH_MANSM  ;  Q5F7W4, GPH_NEIG1  ;
DR   Q9JTP5, GPH_NEIMA  ;  Q2Y6G2, GPH_NITMU  ;  Q3J8A0, GPH_NITOC  ;
DR   Q9CKJ5, GPH_PASMU  ;  Q7NA60, GPH_PHOLL  ;  Q6LVF1, GPH_PHOPR  ;
DR   Q48NS2, GPH_PSE14  ;  Q4K4Z4, GPH_PSEF5  ;  Q3K5U8, GPH_PSEPF  ;
DR   Q88QS2, GPH_PSEPK  ;  P42509, GPH_PSEPU  ;  Q88A30, GPH_PSESM  ;
DR   P42510, GPH_PSESS  ;  Q4ZMI2, GPH_PSEU2  ;  Q4FPT7, GPH_PSYA2  ;
DR   Q98ML8, GPH_RHILO  ;  O33512, GPH_RHOCA  ;  Q2RPW9, GPH_RHORT  ;
DR   A3PNX3, GPH_RHOS1  ;  Q3IYC6, GPH_RHOS4  ;  A4WW31, GPH_RHOS5  ;
DR   P95650, GPH_RHOSH  ;  B9KQ02, GPH_RHOSK  ;  Q57IZ2, GPH_SALCH  ;
DR   Q5PLX6, GPH_SALPA  ;  Q8Z202, GPH_SALTI  ;  Q8ZLK5, GPH_SALTY  ;
DR   Q31VP9, GPH_SHIBS  ;  Q32AJ7, GPH_SHIDS  ;  Q83PX1, GPH_SHIFL  ;
DR   Q3YWN8, GPH_SHISS  ;  Q55039, GPH_SYNE7  ;  Q3SGR5, GPH_THIDA  ;
DR   Q9KNV6, GPH_VIBCH  ;  Q5E2G4, GPH_VIBF1  ;  Q87L12, GPH_VIBPA  ;
DR   Q8DCT7, GPH_VIBVU  ;  Q7MH14, GPH_VIBVY  ;  Q4UVL3, GPH_XANC8  ;
DR   Q8P8H3, GPH_XANCP  ;  Q9PAM6, GPH_XYLFA  ;  Q87BG6, GPH_XYLFT  ;
DR   Q8ZJF3, GPH_YERPE  ;  Q664M4, GPH_YERPS  ;  P95967, PGP1_SULSO ;
DR   P95931, PGP2_SULSO ;  Q9YE03, PGP_AERPE  ;  O29805, PGP_ARCFU  ;
DR   Q2T9S4, PGP_BOVIN  ;  Q5F4B1, PGP_CHICK  ;  B9LMX5, PGP_HALLT  ;
DR   Q5V1R7, PGP_HALMA  ;  B0R403, PGP_HALS3  ;  Q9HRF9, PGP_HALSA  ;
DR   A6NDG6, PGP_HUMAN  ;  Q8TK72, PGP_METAC  ;  Q12UG6, PGP_METBU  ;
DR   Q2FU45, PGP_METHJ  ;  Q8TYT9, PGP_METKA  ;  Q8PZN6, PGP_METMA  ;
DR   A3CWU5, PGP_METMJ  ;  A5ULS3, PGP_METS3  ;  A4YIL7, PGP_METS5  ;
DR   O27143, PGP_METTH  ;  A0B7J8, PGP_METTP  ;  Q8CHP8, PGP_MOUSE  ;
DR   Q3ISC7, PGP_NATPD  ;  A9A492, PGP_NITMS  ;  Q6KZ42, PGP_PICTO  ;
DR   Q9V0Q4, PGP_PYRAB  ;  Q8ZT04, PGP_PYRAE  ;  Q8U111, PGP_PYRFU  ;
DR   O50129, PGP_PYRHO  ;  A1RSN2, PGP_PYRIL  ;  Q5JDB7, PGP_PYRKO  ;
DR   A3DNN7, PGP_STAMF  ;  Q4J8P4, PGP_SULAC  ;  Q96YM5, PGP_SULTO  ;
DR   Q9HLQ2, PGP_THEAC  ;  B1YDE0, PGP_THENV  ;  C6A1L0, PGP_THESM  ;
DR   Q97C22, PGP_THEVO  ;
//
ID   3.1.3.19
DE   Glycerol-2-phosphatase.
CA   Glycerol 2-phosphate + H(2)O = glycerol + phosphate.
//
ID   3.1.3.20
DE   Phosphoglycerate phosphatase.
CA   D-glycerate 2-phosphate + H(2)O = D-glycerate + phosphate.
//
ID   3.1.3.21
DE   Glycerol-1-phosphatase.
CA   Glycerol 1-phosphate + H(2)O = glycerol + phosphate.
CC   -!- The Dunaliella enzyme acts more rapidly on sn-glycerol 1-phosphate
CC       than on the 3-phosphate.
CC   -!- The enzyme from Saccharomyces cerevisiae also acts on propane-1,2-
CC       diol 1-phosphate, but not on a variety of other phosphate esters.
//
ID   3.1.3.22
DE   Mannitol-1-phosphatase.
CA   D-mannitol 1-phosphate + H(2)O = D-mannitol + phosphate.
//
ID   3.1.3.23
DE   Sugar-phosphatase.
CA   Sugar phosphate + H(2)O = sugar + phosphate.
CC   -!- Has a wide specificity, acting on aldohexose 1-phosphates, ketohexose
CC       1-phosphates, aldohexose 6-phosphates, ketohexose 6-phosphates, both
CC       phosphate ester bonds of fructose 1,6-bisphosphate, phosphoric esters
CC       of disaccharides, and on pentose and triose phosphates, but at a
CC       slower rate.
PR   PROSITE; PDOC00944;
DR   P75792, SUPH_ECOLI ;
//
ID   3.1.3.24
DE   Sucrose-phosphate phosphatase.
AN   SPP.
AN   Sucrose-6-phosphate phosphatase.
AN   Sucrose-phosphatase.
CA   Sucrose 6(F)-phosphate + H(2)O = sucrose + phosphate.
CF   Magnesium.
CC   -!- This is the final step in the sucrose-biosynthesis pathway.
CC   -!- Highly specific for sucrose 6-phosphate, with fructose 6-phosphate
CC       unable to act as a substrate.
CC   -!- The F in sucrose 6(F)-phosphate is used to indicate that the fructose
CC       residue of sucrose carries the substituent.
DR   Q9C8J4, SPP1_ARATH ;  Q9FQ11, SPP1_MAIZE ;  Q94E75, SPP1_ORYSJ ;
DR   Q5IH14, SPP1_TOBAC ;  Q9SJ66, SPP2_ARATH ;  Q84ZX8, SPP2_MAIZE ;
DR   Q6YXW6, SPP2_ORYSJ ;  Q5IH13, SPP2_TOBAC ;  Q93WU4, SPP3A_ARATH;
DR   Q93XN8, SPP3B_ARATH;  A3AZW5, SPP3_ORYSJ ;
//
ID   3.1.3.25
DE   Inositol-phosphate phosphatase.
AN   Inositol 1-phosphatase.
AN   Inositol monophosphate phosphatase.
AN   Inositol phosphatase.
AN   Inositol-1(or 4)-monophosphatase.
AN   L-myo-inositol-1-phosphate phosphatase.
AN   Myo-inositol 1-phosphatase.
AN   Myo-inositol monophosphatase.
AN   Myo-inositol-1(or 4)-monophosphatase.
AN   Myo-inositol-1(or 4)-phosphate phosphohydrolase.
AN   Myo-inositol-1-phosphatase.
CA   Myo-inositol phosphate + H(2)O = myo-inositol + phosphate.
CC   -!- Acts on five of the six isomers of myo-inositol phosphate, all except
CC       myo-inositol 2-phosphate, but does not act on myo-inositol bearing
CC       more than one phosphate group.
CC   -!- It also acts on adenosine 2'-phosphate (but not the 3'- or
CC       5'-phosphates), sn-glycerol 3-phosphate and glycerol 2-phosphate,
CC       but does not act on inositol bisphosphates or more phosphorylated
CC       inositols.
PR   PROSITE; PDOC00547;
DR   P65164, CYSQ_MYCBO ;  P46726, CYSQ_MYCLE ;  P65163, CYSQ_MYCTU ;
DR   P54926, IMP1_SOLLC ;  P54927, IMP2_SOLLC ;  P54928, IMP3_SOLLC ;
DR   P20456, IMPA1_BOVIN;  Q19420, IMPA1_CAEEL;  Q54U72, IMPA1_DICDI;
DR   P29218, IMPA1_HUMAN;  O55023, IMPA1_MOUSE;  O77591, IMPA1_PIG  ;
DR   Q5R4X0, IMPA1_PONAB;  P97697, IMPA1_RAT  ;  P29219, IMPA1_XENLA;
DR   O14732, IMPA2_HUMAN;  Q91UZ5, IMPA2_MOUSE;  Q8CIN7, IMPA2_RAT  ;
DR   Q2KJ53, IMPA3_BOVIN;  Q2YDR3, IMPA3_DANRE;  Q9VYF2, IMPA3_DROME;
DR   Q29JH0, IMPA3_DROPS;  Q9NX62, IMPA3_HUMAN;  Q80V26, IMPA3_MOUSE;
DR   Q6NTW5, IMPA3_XENLA;  Q28CL4, IMPA3_XENTR;  A0QX86, IMPA_MYCS2 ;
DR   O53907, IMPA_MYCTU ;  Q94F00, IMPL1_ARATH;  Q6NPM8, IMPL2_ARATH;
DR   O49071, IMPP_MESCR ;  P38710, INM1_YEAST ;  Q05533, INM2_YEAST ;
DR   Q9YAZ7, SUHB_AERPE ;  O67791, SUHB_AQUAE ;  O30298, SUHB_ARCFU ;
DR   Q45499, SUHB_BACSU ;  P57372, SUHB_BUCAI ;  Q8K9P6, SUHB_BUCAP ;
DR   Q89AK9, SUHB_BUCBP ;  Q9A3D5, SUHB_CAUCR ;  P0ADG6, SUHB_ECO57 ;
DR   P0ADG5, SUHB_ECOL6 ;  P0ADG4, SUHB_ECOLI ;  P44333, SUHB_HAEIN ;
DR   Q57573, SUHB_METJA ;  O26957, SUHB_METTH ;  P65166, SUHB_MYCBO ;
DR   P46813, SUHB_MYCLE ;  P65165, SUHB_MYCTU ;  Q9JU03, SUHB_NEIMA ;
DR   Q9JZ07, SUHB_NEIMB ;  Q9CNV8, SUHB_PASMU ;  Q9HXI4, SUHB_PSEAE ;
DR   Q98F59, SUHB_RHILO ;  Q92M71, SUHB_RHIME ;  P58537, SUHB_SALTY ;
DR   P74158, SUHB_SYNY3 ;  O33832, SUHB_THEMA ;  Q9KTY5, SUHB_VIBCH ;
DR   Q9PAM0, SUHB_XYLFA ;  Q87BG1, SUHB_XYLFT ;  Q9M8S8, VTC4_ARATH ;
//
ID   3.1.3.26
DE   4-phytase.
AN   6-phytase (name based on 1L-numbering system and not 1D-numbering).
AN   Phytase.
AN   Phytate 6-phosphatase.
CA   Myo-inositol hexakisphosphate + H(2)O = 1D-myo-inositol 1,2,3,5,6-
CA   pentakisphosphate + phosphate.
DR   P07102, PPA_ECOLI  ;
//
ID   3.1.3.27
DE   Phosphatidylglycerophosphatase.
CA   Phosphatidylglycerophosphate + H(2)O = phosphatidylglycerol + phosphate.
DR   Q9Y7U3, GEP4_SCHPO ;  P38812, GEP4_YEAST ;  P18200, PGPA_ECOLI ;
DR   P44157, PGPA_HAEIN ;  P0A925, PGPB_ECO57 ;  P0A924, PGPB_ECOLI ;
DR   P44570, PGPB_HAEIN ;  P0A926, PGPB_SHIFL ;
//
ID   3.1.3.28
DE   ADP-phosphoglycerate phosphatase.
CA   3-(ADP)-2-phosphoglycerate + H(2)O = 3-(ADP)-glycerate + phosphate.
CC   -!- Also acts on 2,3-diphosphoglycerate.
//
ID   3.1.3.29
DE   N-acylneuraminate-9-phosphatase.
CA   N-acylneuraminate 9-phosphate + H(2)O = N-acylneuraminate + phosphate.
DR   Q8TBE9, NANP_HUMAN ;  Q9CPT3, NANP_MOUSE ;  Q5M969, NANP_RAT   ;
//
ID   3.1.3.30
DE   Transferred entry: 3.1.3.31.
//
ID   3.1.3.31
DE   Nucleotidase.
CA   A nucleotide + H(2)O = a nucleoside + phosphate.
CC   -!- A wide specificity for 2', 3'- and 5'- nucleotides; also hydrolyzes
CC       glycerol phosphate and 4-nitrophenyl phosphate.
CC   -!- Formerly EC 3.1.3.30.
//
ID   3.1.3.32
DE   Polynucleotide 3'-phosphatase.
AN   2'(3')-polynucleotidase.
CA   A 3'-phosphopolynucleotide + H(2)O = a polynucleotide + phosphate.
CC   -!- Also hydrolyzes nucleoside 2'-, 3'- and 5'-monophosphates, but only
CC       2'- and 3'-phosphopolynucleotides.
DR   O13911, PNK1_SCHPO ;  Q96T60, PNKP_HUMAN ;  Q5UQD2, PNKP_MIMIV ;
DR   Q9JLV6, PNKP_MOUSE ;  Q9HET9, TPP1_SACMI ;  Q03796, TPP1_YEAST ;
//
ID   3.1.3.33
DE   Polynucleotide 5'-phosphatase.
AN   5'-polynucleotidase.
AN   Polynucleotide 5'-triphosphatase.
CA   A 5'-phosphopolynucleotide + H(2)O = a polynucleotide + phosphate.
CC   -!- Does not act on nucleoside monophosphates.
CC   -!- Induced in Escherichia coli by T-even phages.
DR   Q755F7, CET1_ASHGO ;  O93803, CET1_CANAL ;  Q6FUZ2, CET1_CANGA ;
DR   Q5KEQ1, CET1_CRYNJ ;  Q6BND2, CET1_DEBHA ;  Q6CT22, CET1_KLULA ;
DR   Q9P6Q6, CET1_SCHPO ;  Q6C2H4, CET1_YARLI ;  O13297, CET1_YEAST ;
DR   Q03220, CTL1_YEAST ;  Q17607, MCE1_CAEEL ;  Q6NY98, MCE1_DANRE ;
DR   O60942, MCE1_HUMAN ;  O55236, MCE1_MOUSE ;  Q8V2R8, MCEL_CAMPM ;
DR   Q775U0, MCEL_CAMPS ;  Q8QMV9, MCEL_CWPXB ;  Q80DX6, MCEL_CWPXG ;
DR   Q9J584, MCEL_FOWPN ;  P25950, MCEL_RFVKA ;  O57209, MCEL_VACCA ;
DR   P20979, MCEL_VACCC ;  Q9JFA8, MCEL_VACCT ;  P04298, MCEL_VACCW ;
DR   P33057, MCEL_VAR67 ;  Q5UQX1, MCE_MIMIV  ;  Q86924, POLN_AURAV ;
DR   P87515, POLN_BFV   ;  Q5XXP4, POLN_CHIK3 ;  Q8JUX6, POLN_CHIKS ;
DR   Q306W6, POLN_EEEV1 ;  Q306W8, POLN_EEEV8 ;  Q4QXJ8, POLN_EEEVF ;
DR   P36327, POLN_EEVV3 ;  Q8V294, POLN_EEVVC ;  Q9WJC7, POLN_EEVVM ;
DR   P36328, POLN_EEVVP ;  P27282, POLN_EEVVT ;  Q5Y389, POLN_GETV  ;
DR   Q8QZ73, POLN_MAYAB ;  P13886, POLN_ONNVG ;  O90370, POLN_ONNVI ;
DR   O90368, POLN_ONNVS ;  P13887, POLN_RRVN  ;  Q9JGL0, POLN_SAGV  ;
DR   P08411, POLN_SFV   ;  P27283, POLN_SINDO ;  P03317, POLN_SINDV ;
DR   Q8QL53, POLN_SLDV  ;  Q8JJX1, POLN_SPDV  ;  P13896, POLN_WEEV  ;
//
ID   3.1.3.34
DE   Deoxynucleotide 3'-phosphatase.
AN   3'-deoxynucleotidase.
CA   A deoxynucleoside 3'-phosphate + H(2)O = a deoxynucleoside + phosphate.
CC   -!- Also catalyzes the selective removal of 3'-phosphate groups from DNA
CC       and oligodeoxynucleotides.
CC   -!- Induced in Escherichia coli by T-even phages.
//
ID   3.1.3.35
DE   Thymidylate 5'-phosphatase.
AN   Thymidylate 5'-nucleotidase.
CA   Thymidylate + H(2)O = thymidine + phosphate.
CC   -!- Acts on 5-methyl-dCMP and on TMP, but more slowly than on dTMP.
//
ID   3.1.3.36
DE   Phosphoinositide 5-phosphatase.
AN   Diphosphoinositide phosphatase.
AN   Inositol 1,4,5-triphosphate 5-phosphomonoesterase.
AN   Inositol triphosphate 5-phosphomonoesterase.
AN   IP(3) phosphatase.
AN   Phosphatidyl-inositol-bisphosphate phosphatase.
AN   Phosphatidyl-myo-inositol-4,5-bisphosphate phosphatase.
AN   Phosphatidylinositol 4,5-bisphosphate phosphatase.
AN   Phosphatidylinositol-bisphosphatase.
AN   Polyphosphoinositol lipid 5-phosphatase.
AN   PtdIns(4,5)P(2) phosphatase.
AN   Triphosphoinositide phosphatase.
AN   Triphosphoinositide phosphomonoesterase.
AN   Type II inositol polyphosphate 5-phosphatase.
AN   Type II inositol-1,4,5-trisphosphate 5-phosphatase.
CA   1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-
CA   1D-myo-inositol 4-phosphate + phosphate.
CC   -!- These enzymes can also remove the 5-phosphate from Ins(1,4,5)P(3)
CC       and/or Ins(1,3,4,5)P(4).
CC   -!- They are a diverse family of enzymes, with differing abilities to
CC       catalyze two or more of the four reactions listed.
CC   -!- They are thought to use inositol lipids rather than inositol
CC       phosphates as substrates in vivo.
CC   -!- All of them can use either or both of PtdIns(4,5)P(2) and
CC       PtdIns(3,4,5)P(3) as substrates; this is the main property that
CC       distinguishes them from EC 3.1.3.56.
DR   P32019, I5P2_HUMAN ;  P40559, INP51_YEAST;  P50942, INP52_YEAST;
DR   Q12271, INP53_YEAST;  Q08227, INP54_YEAST;  Q9NRR6, INP5E_HUMAN;
DR   Q9JII1, INP5E_MOUSE;  A0FI79, INP5E_PANTR;  Q9WVR1, INP5E_RAT  ;
DR   Q84W55, IP5P4_ARATH;  Q9SKB7, IP5PE_ARATH;  Q01968, OCRL_HUMAN ;
DR   O43001, SYJ1_SCHPO ;  Q9USQ6, SYJ2_SCHPO ;  O18964, SYNJ1_BOVIN;
DR   O43426, SYNJ1_HUMAN;  Q8CHC4, SYNJ1_MOUSE;  Q62910, SYNJ1_RAT  ;
DR   O15056, SYNJ2_HUMAN;  Q9D2G5, SYNJ2_MOUSE;  O55207, SYNJ2_RAT  ;
//
ID   3.1.3.37
DE   Sedoheptulose-bisphosphatase.
AN   Sedoheptulose-1,7-bisphosphatase.
CA   Sedoheptulose 1,7-bisphosphate + H(2)O = sedoheptulose 7-phosphate +
CA   phosphate.
PR   PROSITE; PDOC00114;
DR   B0C1Z3, FBSB1_ACAM1;  B0BZF8, FBSB2_ACAM1;  Q3M6T3, FBSB_ANAVT ;
DR   B1WQ07, FBSB_CYAA5 ;  Q7NG31, FBSB_GLOVI ;  B0JKN5, FBSB_MICAN ;
DR   Q8YY12, FBSB_NOSS1 ;  A3PCH5, FBSB_PROM0 ;  A2C1K3, FBSB_PROM1 ;
DR   A8G4E5, FBSB_PROM2 ;  A2CAB7, FBSB_PROM3 ;  A2BW64, FBSB_PROM5 ;
DR   Q31BB0, FBSB_PROM9 ;  Q7TVA4, FBSB_PROMA ;  Q7V808, FBSB_PROMM ;
DR   Q7V1T8, FBSB_PROMP ;  A2BQQ2, FBSB_PROMS ;  Q46LG3, FBSB_PROMT ;
DR   Q31QY2, FBSB_SYNE7 ;  Q2JWU7, FBSB_SYNJA ;  Q2JJG9, FBSB_SYNJB ;
DR   B1XLK5, FBSB_SYNP2 ;  Q5N3B5, FBSB_SYNP6 ;  Q7U770, FBSB_SYNPX ;
DR   A5GTE9, FBSB_SYNR3 ;  Q0I9I3, FBSB_SYNS3 ;  Q3AXK3, FBSB_SYNS9 ;
DR   Q3AK74, FBSB_SYNSC ;  P73922, FBSB_SYNY3 ;  Q8DJE9, FBSB_THEEB ;
DR   Q117I5, FBSB_TRIEI ;  P46283, S17P_ARATH ;  P46284, S17P_CHLRE ;
DR   O20252, S17P_SPIOL ;  P46285, S17P_WHEAT ;
//
ID   3.1.3.38
DE   3-phosphoglycerate phosphatase.
CA   D-glycerate 3-phosphate + H(2)O = D-glycerate + phosphate.
CC   -!- Wide specificity, but 3-phosphoglycerate is the best substrate.
//
ID   3.1.3.39
DE   Streptomycin-6-phosphatase.
CA   Streptomycin 6-phosphate + H(2)O = streptomycin + phosphate.
CC   -!- Also acts on dihydrostreptomycin 3'-alpha,6-bisphosphate and
CC       streptidine 6-phosphate.
PR   PROSITE; PDOC00113;
DR   P09401, STRK_STRGR ;
//
ID   3.1.3.40
DE   Guanidinodeoxy-scyllo-inositol-4-phosphatase.
CA   1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H(2)O = 1-guanidino-1-
CA   deoxy-scyllo-inositol + phosphate.
//
ID   3.1.3.41
DE   4-nitrophenylphosphatase.
CA   4-nitrophenyl phosphate + H(2)O = 4-nitrophenol + phosphate.
CC   -!- A number of other substances, including phenyl phosphate,
CC       4-nitrophenyl sulfate, acetyl phosphate and glycerol phosphate,
CC       are not substrates.
DR   Q00472, PNPP_SCHPO ;  P19881, PNPP_YEAST ;
//
ID   3.1.3.42
DE   [Glycogen-synthase-D] phosphatase.
CA   [Glycogen-synthase D] + H(2)O = [glycogen-synthase I] + phosphate.
CC   -!- The product is EC 2.4.1.11.
//
ID   3.1.3.43
DE   [Pyruvate dehydrogenase (acetyl-transferring)]-phosphatase.
CA   [Pyruvate dehydrogenase (acetyl-transferring)] phosphate + H(2)O =
CA   [pyruvate dehydrogenase (acetyl-transferring)] + phosphate.
CC   -!- A mitochondrial enzyme associated with EC 1.2.4.1 in the pyruvate
CC       dehydrogenase complex.
PR   PROSITE; PDOC00792;
DR   P35816, PDP1_BOVIN ;  Q9P0J1, PDP1_HUMAN ;  Q3UV70, PDP1_MOUSE ;
DR   Q5RA52, PDP1_PONAB ;  O88483, PDP1_RAT   ;  Q9P2J9, PDP2_HUMAN ;
DR   O88484, PDP2_RAT   ;
//
ID   3.1.3.44
DE   [Acetyl-CoA carboxylase]-phosphatase.
CA   [Acetyl-CoA carboxylase] phosphate + H(2)O = [acetyl-CoA carboxylase] +
CA   phosphate.
CC   -!- Simultaneously dephosphorylates and activates EC 6.4.1.2.
CC   -!- Acts similarly on EC 1.1.1.88, EC 2.4.1.1 and EC 2.4.1.11,
CC       and dephosphorylates phosphoprotamine and 4-nitrophenyl phosphate.
CC   -!- Not identical with EC 3.1.3.17 or EC 3.1.3.43.
//
ID   3.1.3.45
DE   3-deoxy-manno-octulosonate-8-phosphatase.
CA   3-deoxy-D-manno-octulosonate 8-phosphate + H(2)O = 3-deoxy-D-manno-
CA   octulosonate + phosphate.
DR   P0ABZ5, KDSC_ECO57 ;  P67653, KDSC_ECOL6 ;  P0ABZ4, KDSC_ECOLI ;
DR   P45314, KDSC_HAEIN ;  Q8Z3G5, KDSC_SALTI ;  Q8ZLS0, KDSC_SALTY ;
DR   P67654, KDSC_SHIFL ;  Q8ZB47, KDSC_YERPE ;
//
ID   3.1.3.46
DE   Fructose-2,6-bisphosphate 2-phosphatase.
AN   Fructose-2,6-bisphosphatase.
CA   Beta-D-fructose 2,6-bisphosphate + H(2)O = D-fructose 6-phosphate +
CA   phosphate.
CC   -!- The enzyme copurifies with EC 2.7.1.105 (cf. EC 3.1.3.54).
PR   PROSITE; PDOC00158;
DR   P49872, F261_BOVIN ;  P16118, F261_HUMAN ;  P70266, F261_MOUSE ;
DR   P07953, F261_RAT   ;  P26285, F262_BOVIN ;  O60825, F262_HUMAN ;
DR   P70265, F262_MOUSE ;  Q5NVT1, F262_PONAB ;  Q9JJH5, F262_RAT   ;
DR   Q28901, F263_BOVIN ;  Q16875, F263_HUMAN ;  Q5R9C1, F263_PONAB ;
DR   O35552, F263_RAT   ;  Q16877, F264_HUMAN ;  Q4R8B6, F264_MACFA ;
DR   Q6DTY7, F264_MOUSE ;  P25114, F264_RAT   ;  Q91348, F26L_CHICK ;
DR   Q21122, F26_CAEEL  ;  Q91309, F26_RANCA  ;  P32604, F26_YEAST  ;
DR   Q1JQA7, TIGAR_BOVIN;  Q9NQ88, TIGAR_HUMAN;  Q8BZA9, TIGAR_MOUSE;
DR   Q4V7R0, TIGAR_XENLA;  B1WAX6, TIGAR_XENTR;  Q29RA5, TIGRA_DANRE;
DR   Q7ZVE3, TIGRB_DANRE;  Q9UTK9, YIVH_SCHPO ;  Q9URZ7, YK72_SCHPO ;
DR   Q06137, YL345_YEAST;
//
ID   3.1.3.47
DE   [Hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase.
AN   Reductase phosphatase.
CA   [Hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H(2)O =
CA   [hydroxymethylglutaryl-CoA reductase (NADPH)] + phosphate.
CC   -!- Acts on the product of the reaction catalyzed by EC 2.7.11.31,
CC       simultaneously dephosphorylating and activating EC 1.1.1.34.
//
ID   3.1.3.48
DE   Protein-tyrosine-phosphatase.
AN   Phosphotyrosine phosphatase.
AN   PTPase.
CA   Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
CC   -!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as
CC       the products of EC 2.7.10.2.
PR   PROSITE; PDOC00323;
DR   Q46630, AMSI_ERWAM ;  Q74NT6, ARSC1_BACC1;  Q5HRI4, ARSC1_STAEQ;
DR   Q4LAB5, ARSC1_STAHJ;  Q49WS7, ARSC1_STAS1;  Q735E5, ARSC2_BACC1;
DR   Q5HKB7, ARSC2_STAEQ;  Q4LAA8, ARSC2_STAHJ;  Q49UH1, ARSC2_STAS1;
DR   C3P101, ARSC_BACAA ;  C3LDK1, ARSC_BACAC ;  Q81NJ6, ARSC_BACAN ;
DR   B7INE4, ARSC_BACC2 ;  C1F0A7, ARSC_BACC3 ;  B7HWU2, ARSC_BACC7 ;
DR   A7GP55, ARSC_BACCN ;  B9IRF0, ARSC_BACCQ ;  Q81BK3, ARSC_BACCR ;
DR   Q639D2, ARSC_BACCZ ;  Q9K8K8, ARSC_BACHD ;  Q6HGP0, ARSC_BACHK ;
DR   Q65IV4, ARSC_BACLD ;  Q8GJ74, ARSC_BACMD ;  Q5WJS9, ARSC_BACSK ;
DR   P45947, ARSC_BACSU ;  C0ZEV2, ARSC_BREBN ;  A4INR2, ARSC_GEOTN ;
DR   B9E7M5, ARSC_MACCJ ;  Q8ENQ5, ARSC_OCEIH ;  Q2FFW6, ARSC_STAA3 ;
DR   Q2FXF5, ARSC_STAA8 ;  Q2YTL3, ARSC_STAAB ;  Q5HF01, ARSC_STAAC ;
DR   A6QHV6, ARSC_STAAE ;  P0A005, ARSC_STAAN ;  Q6GIZ3, ARSC_STAAR ;
DR   A8Z4K0, ARSC_STAAT ;  P0A006, ARSC_STAAU ;  Q8CQF5, ARSC_STAES ;
DR   Q01257, ARSC_STAXY ;  Q27974, AUXI_BOVIN ;  O75061, AUXI_HUMAN ;
DR   Q80TZ3, AUXI_MOUSE ;  P39852, CAPC_STAAU ;  Q9UNH5, CC14A_HUMAN;
DR   Q6GQT0, CC14A_MOUSE;  O60729, CC14B_HUMAN;  Q6PFY9, CC14B_MOUSE;
DR   A4D256, CC14C_HUMAN;  A6N3Q4, CC14C_HYLSY;  P81299, CDC14_CAEEL;
DR   Q00684, CDC14_YEAST;  Q8GY31, CDC25_ARATH;  Q16667, CDKN3_HUMAN;
DR   Q810P3, CDKN3_MOUSE;  Q9MYN5, CDKN3_PIG  ;  B2RZ50, CDKN3_RAT  ;
DR   Q9AHD4, CPSB1_STRPN;  Q54518, CPSB2_STRPN;  Q3K0S8, CPSB_STRA1 ;
DR   Q04661, CPSB_STRA3 ;  P0A364, CPSB_STRA5 ;  P0C0T7, CPSB_STRAG ;
DR   P29349, CSW_DROME  ;  Q8ISC9, CSW_DROSI  ;  Q24708, CSW_DROVI  ;
DR   Q1ZXG8, D1060_DICDI;  Q1LWL2, DS22A_DANRE;  Q566R7, DS22B_DANRE;
DR   P0C598, DUPD1_ANOCA;  P0C591, DUPD1_BOVIN;  P0C5A2, DUPD1_CALMI;
DR   P0C597, DUPD1_CHICK;  Q29RA3, DUPD1_DANRE;  P0C5A0, DUPD1_GASAC;
DR   P0C592, DUPD1_HORSE;  Q68J44, DUPD1_HUMAN;  P0C593, DUPD1_MONDO;
DR   Q8BK84, DUPD1_MOUSE;  P0C5A1, DUPD1_ORYLA;  P0C594, DUPD1_PANTR;
DR   P0C596, DUPD1_PIG  ;  P0C595, DUPD1_RAT  ;  P0C599, DUPD1_TAKRU;
DR   Q4RQD3, DUPD1_TETNG;  Q4KL92, DUPD1_XENLA;  A4IHU7, DUPD1_XENTR;
DR   Q0IID7, DUS10_BOVIN;  Q9Y6W6, DUS10_HUMAN;  Q9ESS0, DUS10_MOUSE;
DR   Q9UNI6, DUS12_HUMAN;  Q9D0T2, DUS12_MOUSE;  Q9JIM4, DUS12_RAT  ;
DR   Q9UII6, DUS13_HUMAN;  Q9QYJ7, DUS13_MOUSE;  Q17QM8, DUS14_BOVIN;
DR   O95147, DUS14_HUMAN;  Q9JLY7, DUS14_MOUSE;  Q9H1R2, DUS15_HUMAN;
DR   Q8R4V2, DUS15_MOUSE;  Q9BY84, DUS16_HUMAN;  Q5BIP9, DUS18_BOVIN;
DR   Q8NEJ0, DUS18_HUMAN;  Q8VE01, DUS18_MOUSE;  Q5R8X2, DUS18_PONAB;
DR   Q6AXW7, DUS18_RAT  ;  Q8WTR2, DUS19_HUMAN;  Q8K4T5, DUS19_MOUSE;
DR   P28562, DUS1_HUMAN ;  P28563, DUS1_MOUSE ;  Q64623, DUS1_RAT   ;
DR   Q9H596, DUS21_HUMAN;  Q9D9D8, DUS21_MOUSE;  Q9NRW4, DUS22_HUMAN;
DR   Q99N11, DUS22_MOUSE;  Q6GQJ8, DUS22_XENLA;  Q5XHB2, DUS22_XENTR;
DR   Q9BVJ7, DUS23_HUMAN;  Q6NT99, DUS23_MOUSE;  Q17QJ3, DUS26_BOVIN;
DR   Q9BV47, DUS26_HUMAN;  Q9D700, DUS26_MOUSE;  Q5R6H6, DUS26_PONAB;
DR   Q5FVI9, DUS26_RAT  ;  Q4G0W2, DUS28_HUMAN;  Q8BTR5, DUS28_MOUSE;
DR   Q05923, DUS2_HUMAN ;  Q05922, DUS2_MOUSE ;  P51452, DUS3_HUMAN ;
DR   Q9D7X3, DUS3_MOUSE ;  Q5RD73, DUS3_PONAB ;  Q9PW71, DUS4_CHICK ;
DR   Q13115, DUS4_HUMAN ;  Q8BFV3, DUS4_MOUSE ;  Q62767, DUS4_RAT   ;
DR   Q16690, DUS5_HUMAN ;  O54838, DUS5_RAT   ;  Q2KJ36, DUS6_BOVIN ;
DR   Q16828, DUS6_HUMAN ;  Q9DBB1, DUS6_MOUSE ;  Q64346, DUS6_RAT   ;
DR   Q16829, DUS7_HUMAN ;  Q91Z46, DUS7_MOUSE ;  Q63340, DUS7_RAT   ;
DR   Q13202, DUS8_HUMAN ;  O09112, DUS8_MOUSE ;  Q99956, DUS9_HUMAN ;
DR   Q9VVW5, DUSK3_DROME;  Q55E39, DUSP1_DICDI;  Q54R42, DUSP2_DICDI;
DR   Q55BI8, DUSP3_DICDI;  Q54T76, DUSP4_DICDI;  Q556Y8, DUSPR_DICDI;
DR   Q9J592, DUSP_FOWPN ;  Q85297, DUSP_MYXVL ;  P20495, DUSP_VACCC ;
DR   P07239, DUSP_VACCW ;  P33064, DUSP_VAR67 ;  Q1M199, EPM2A_CANFA;
DR   O95278, EPM2A_HUMAN;  Q9WUA5, EPM2A_MOUSE;  Q91XQ2, EPM2A_RAT  ;
DR   P58596, EPSP1_RALSO;  Q45408, EPSP2_RALSO;  P0ACZ3, ETP_ECO57  ;
DR   P0ACZ2, ETP_ECOLI  ;  Q9YHA0, EYA1_CHICK ;  Q99502, EYA1_HUMAN ;
DR   P97767, EYA1_MOUSE ;  Q58DB6, EYA2_BOVIN ;  O00167, EYA2_HUMAN ;
DR   O08575, EYA2_MOUSE ;  Q9YH99, EYA3_CHICK ;  Q99504, EYA3_HUMAN ;
DR   P97480, EYA3_MOUSE ;  Q9YH98, EYA4_CHICK ;  O95677, EYA4_HUMAN ;
DR   Q9Z191, EYA4_MOUSE ;  Q9YHA1, EYA4_TAKRU ;  Q05201, EYA_DROME  ;
DR   Q9P7H1, FLP1_SCHPO ;  Q79LY0, HOPD2_PSESM;  Q8WZK3, IBP1_SCHPO ;
DR   Q84JU4, IBR5_ARATH ;  Q05918, IPHP_NOSCO ;  Q9BMN8, LAR_CAEEL  ;
DR   P16621, LAR_DROME  ;  Q6B8I1, MDSP_HUMAN ;  Q6B8I0, MDSP_MOUSE ;
DR   Q86V88, MGDP1_HUMAN;  Q9D967, MGDP1_MOUSE;  O94279, MGDP1_SCHPO;
DR   P40081, MGDP1_YEAST;  P30308, MPI1A_XENLA;  P30309, MPI1B_XENLA;
DR   A7MBD1, MPIP1_BOVIN;  O44552, MPIP1_CAEEL;  P30304, MPIP1_HUMAN;
DR   P48964, MPIP1_MOUSE;  P48965, MPIP1_RAT  ;  O44628, MPIP2_CAEEL;
DR   P30305, MPIP2_HUMAN;  P30306, MPIP2_MOUSE;  P48966, MPIP2_RAT  ;
DR   P30310, MPIP2_XENLA;  A5D7P0, MPIP3_BOVIN;  P30634, MPIP3_CAEEL;
DR   P30307, MPIP3_HUMAN;  P48968, MPIP3_MESAU;  P48967, MPIP3_MOUSE;
DR   Q29029, MPIP3_PIG  ;  P30311, MPIP3_XENLA;  Q54QM6, MPIP_DICDI ;
DR   P20483, MPIP_DROME ;  P30303, MPIP_EMENI ;  P06652, MPIP_SCHPO ;
DR   P23748, MPIP_YEAST ;  Q55CS7, MPL1_DICDI ;  Q55CS8, MPL2_DICDI ;
DR   Q54Y32, MPL3_DICDI ;  P38590, MSG5_YEAST ;  Q22712, MTMR3_CAEEL;
DR   Q13615, MTMR3_HUMAN;  Q8K296, MTMR3_MOUSE;  Q5PQT2, MTMR3_RAT  ;
DR   Q9NYA4, MTMR4_HUMAN;  Q91XS1, MTMR4_MOUSE;  Q7ZXF1, MTMR4_XENLA;
DR   Q75B37, OCA1_ASHGO ;  Q59XY9, OCA1_CANAL ;  Q6FSZ8, OCA1_CANGA ;
DR   Q6BLZ8, OCA1_DEBHA ;  Q6CTE4, OCA1_KLULA ;  A5DE24, OCA1_PICGU ;
DR   A3LW52, OCA1_PICST ;  Q4P7L6, OCA1_USTMA ;  Q6C4X9, OCA1_YARLI ;
DR   A6ZRY1, OCA1_YEAS7 ;  P50946, OCA1_YEAST ;  Q12454, OCA6_YEAST ;
DR   O13453, PMP1_SCHPO ;  P82890, PPAC1_DROME;  P82891, PPAC2_DROME;
DR   P11064, PPAC_BOVIN ;  Q5ZKG5, PPAC_CHICK ;  Q55GW2, PPAC_DICDI ;
DR   P24666, PPAC_HUMAN ;  Q9D358, PPAC_MOUSE ;  P81693, PPAC_PIG   ;
DR   Q5REM7, PPAC_PONAB ;  P41498, PPAC_RAT   ;  P41893, PPAL_SCHPO ;
DR   P40347, PPAL_YEAST ;  P38148, PPS1_YEAST ;  P60483, PTEN_CANFA ;
DR   Q8T9S7, PTEN_DICDI ;  P60484, PTEN_HUMAN ;  O08586, PTEN_MOUSE ;
DR   Q9PUT6, PTEN_XENLA ;  Q90687, PTN11_CHICK;  Q06124, PTN11_HUMAN;
DR   P35235, PTN11_MOUSE;  P41499, PTN11_RAT  ;  Q05209, PTN12_HUMAN;
DR   P35831, PTN12_MOUSE;  Q12923, PTN13_HUMAN;  Q64512, PTN13_MOUSE;
DR   Q15678, PTN14_HUMAN;  Q62130, PTN14_MOUSE;  Q99952, PTN18_HUMAN;
DR   Q61152, PTN18_MOUSE;  O13016, PTN1_CHICK ;  P18031, PTN1_HUMAN ;
DR   P35821, PTN1_MOUSE ;  P20417, PTN1_RAT   ;  Q4JDL3, PTN20_HUMAN;
DR   O55082, PTN20_MOUSE;  A1L1L3, PTN20_RAT  ;  Q16825, PTN21_HUMAN;
DR   Q62136, PTN21_MOUSE;  Q62728, PTN21_RAT  ;  Q9Y2R2, PTN22_HUMAN;
DR   P29352, PTN22_MOUSE;  Q9H3S7, PTN23_HUMAN;  Q6PB44, PTN23_MOUSE;
DR   O88902, PTN23_RAT  ;  P17706, PTN2_HUMAN ;  Q06180, PTN2_MOUSE ;
DR   P35233, PTN2_RAT   ;  P26045, PTN3_HUMAN ;  P29074, PTN4_HUMAN ;
DR   Q9WU22, PTN4_MOUSE ;  P54829, PTN5_HUMAN ;  P54830, PTN5_MOUSE ;
DR   P35234, PTN5_RAT   ;  P29350, PTN6_HUMAN ;  P29351, PTN6_MOUSE ;
DR   P81718, PTN6_RAT   ;  P35236, PTN7_HUMAN ;  Q8BUM3, PTN7_MOUSE ;
DR   P49445, PTN7_RAT   ;  P43378, PTN9_HUMAN ;  O35239, PTN9_MOUSE ;
DR   Q641Z2, PTN9_RAT   ;  P35992, PTP10_DROME;  P28202, PTP10_STYPL;
DR   P28203, PTP11_STYPL;  P28204, PTP12_STYPL;  P28205, PTP13_STYPL;
DR   P28206, PTP14_STYPL;  P28207, PTP15_STYPL;  P28208, PTP16_STYPL;
DR   P28209, PTP17_STYPL;  P28210, PTP18_STYPL;  P28211, PTP19_STYPL;
DR   P28191, PTP1_CAEEL ;  P34137, PTP1_DICDI ;  O10274, PTP1_NPVOP ;
DR   P28193, PTP1_STYPL ;  P25044, PTP1_YEAST ;  P28212, PTP20_STYPL;
DR   P28213, PTP21_STYPL;  P28214, PTP22_STYPL;  P28215, PTP23_STYPL;
DR   P28216, PTP24_STYPL;  P28217, PTP25_STYPL;  P28218, PTP26_STYPL;
DR   P28219, PTP27_STYPL;  P28192, PTP2_CAEEL ;  P34138, PTP2_DICDI ;
DR   O10273, PTP2_NPVOP ;  P28194, PTP2_STYPL ;  P29461, PTP2_YEAST ;
DR   Q39491, PTP3_CHLMO ;  P54637, PTP3_DICDI ;  P28195, PTP3_STYPL ;
DR   P40048, PTP3_YEAST ;  P34442, PTP4_CAEEL ;  P28196, PTP4_STYPL ;
DR   P28197, PTP5_STYPL ;  Q9W0G1, PTP61_DROME;  P16620, PTP69_DROME;
DR   P28198, PTP6_STYPL ;  P28199, PTP7_STYPL ;  P28200, PTP8_STYPL ;
DR   P35832, PTP99_DROME;  P28201, PTP9_STYPL ;  P65717, PTPA_MYCBO ;
DR   P65716, PTPA_MYCTU ;  Q2FFL4, PTPA_STAA3 ;  Q2FX12, PTPA_STAA8 ;
DR   Q2YU46, PTPA_STAAB ;  Q5HEP3, PTPA_STAAC ;  Q99T00, PTPA_STAAM ;
DR   Q7A4S1, PTPA_STAAN ;  Q6GFH6, PTPA_STAAR ;  Q6G853, PTPA_STAAS ;
DR   P0C5D2, PTPA_STAAU ;  Q7A0I2, PTPA_STAAW ;  Q5HN53, PTPA_STAEQ ;
DR   Q8CNQ1, PTPA_STAES ;  Q4L7J1, PTPA_STAHJ ;  Q49YS6, PTPA_STAS1 ;
DR   P53433, PTPA_STRCO ;  Q2FF13, PTPB_STAA3 ;  Q2FWE3, PTPB_STAA8 ;
DR   Q2YUL3, PTPB_STAAB ;  Q5HE85, PTPB_STAAC ;  Q99SE3, PTPB_STAAM ;
DR   Q7A4E1, PTPB_STAAN ;  Q6GEW0, PTPB_STAAR ;  Q6G7J5, PTPB_STAAS ;
DR   P0C5D3, PTPB_STAAU ;  Q7A0B9, PTPB_STAAW ;  Q5HMA8, PTPB_STAEQ ;
DR   Q8CNI9, PTPB_STAES ;  Q4L7Z6, PTPB_STAHJ ;  Q49Z62, PTPB_STAS1 ;
DR   Q5I146, PTPH2_MDBV ;  Q5I145, PTPH3_MDBV ;  Q5I143, PTPH4_MDBV ;
DR   Q9EMX1, PTPH_AMEPV ;  Q5UR74, PTPH_MIMIV ;  Q5I139, PTPJ2_MDBV ;
DR   Q5I137, PTPJ4_MDBV ;  Q86BN8, PTPM1_DROME;  Q8WUK0, PTPM1_HUMAN;
DR   Q66GT5, PTPM1_MOUSE;  P0C089, PTPM1_RAT  ;  Q5I128, PTPN1_MDBV ;
DR   A2ALK8, PTPN3_MOUSE;  Q92932, PTPR2_HUMAN;  O02695, PTPR2_MACNE;
DR   P80560, PTPR2_MOUSE;  Q63475, PTPR2_RAT  ;  P18433, PTPRA_HUMAN;
DR   P18052, PTPRA_MOUSE;  Q03348, PTPRA_RAT  ;  P23467, PTPRB_HUMAN;
DR   B2RU80, PTPRB_MOUSE;  Q9IBD8, PTPRC_CYPCA;  P08575, PTPRC_HUMAN;
DR   P06800, PTPRC_MOUSE;  P04157, PTPRC_RAT  ;  P23468, PTPRD_HUMAN;
DR   Q64487, PTPRD_MOUSE;  P23469, PTPRE_HUMAN;  P49446, PTPRE_MOUSE;
DR   B2GV87, PTPRE_RAT  ;  A7MBJ4, PTPRF_BOVIN;  A4IFW2, PTPRF_DANRE;
DR   P10586, PTPRF_HUMAN;  A2A8L5, PTPRF_MOUSE;  Q64604, PTPRF_RAT  ;
DR   Q98936, PTPRG_CHICK;  P23470, PTPRG_HUMAN;  Q05909, PTPRG_MOUSE;
DR   Q9HD43, PTPRH_HUMAN;  Q9W6V5, PTPRJ_CHICK;  Q12913, PTPRJ_HUMAN;
DR   Q64455, PTPRJ_MOUSE;  Q15262, PTPRK_HUMAN;  P35822, PTPRK_MOUSE;
DR   P28827, PTPRM_HUMAN;  P28828, PTPRM_MOUSE;  Q16827, PTPRO_HUMAN;
DR   Q9UMZ3, PTPRQ_HUMAN;  P0C5E4, PTPRQ_MOUSE;  O88488, PTPRQ_RAT  ;
DR   Q15256, PTPRR_HUMAN;  Q62132, PTPRR_MOUSE;  O08617, PTPRR_RAT  ;
DR   Q13332, PTPRS_HUMAN;  B0V2N1, PTPRS_MOUSE;  Q64605, PTPRS_RAT  ;
DR   O14522, PTPRT_HUMAN;  Q99M80, PTPRT_MOUSE;  Q6YI48, PTPRU_CHICK;
DR   B3DK56, PTPRU_DANRE;  Q92729, PTPRU_HUMAN;  B1AUH1, PTPRU_MOUSE;
DR   P70289, PTPRV_MOUSE;  Q64612, PTPRV_RAT  ;  P23471, PTPRZ_HUMAN;
DR   Q62656, PTPRZ_RAT  ;  P43078, PTPX_CANAL ;  O52787, PTP_ACIJO  ;
DR   P24656, PTP_NPVAC  ;  O13632, PVH1_SCHPO ;  Q02256, PVH1_YEAST ;
DR   P27574, PYP1_SCHPO ;  P32586, PYP2_SCHPO ;  P32587, PYP3_SCHPO ;
DR   P20402, ROB1_AGRRH ;  P49409, ROB2_AGRRH ;  P09178, ROLB_NICGL ;
DR   P40479, SDP1_YEAST ;  P53965, SIW14_YEAST;  Q5PEA9, SPTP_SALPA ;
DR   P74851, SPTP_SALTI ;  P74873, SPTP_SALTY ;  Q8WYL5, SSH1_HUMAN ;
DR   Q76I79, SSH1_MOUSE ;  Q76I76, SSH2_HUMAN ;  Q5SW75, SSH2_MOUSE ;
DR   Q8TE77, SSH3_HUMAN ;  Q8K330, SSH3_MOUSE ;  Q5XIS1, SSH3_RAT   ;
DR   Q6NN85, SSH_DROME  ;  Q6IVY4, SSH_XENLA  ;  Q93096, TP4A1_HUMAN;
DR   Q9TSM6, TP4A1_MACFA;  Q63739, TP4A1_MOUSE;  Q5R7J8, TP4A1_PONAB;
DR   Q78EG7, TP4A1_RAT  ;  Q12974, TP4A2_HUMAN;  O70274, TP4A2_MOUSE;
DR   Q6P9X4, TP4A2_RAT  ;  A2VDT1, TP4A3_BOVIN;  O75365, TP4A3_HUMAN;
DR   Q9D658, TP4A3_MOUSE;  Q54DU9, TP4AA_DICDI;  Q86IL4, TP4AB_DICDI;
DR   P56180, TPTE_HUMAN ;  Q03019, TWINE_DROME;  Q8TF42, UBS3B_HUMAN;
DR   Q8BGG7, UBS3B_MOUSE;  P80994, VH01_RACVI ;  Q10038, VHP1_CAEEL ;
DR   P54092, VP2_CAV26  ;  P54093, VP2_CAV82  ;  P69484, VP2_CAVC1  ;
DR   Q9IZU7, VP2_CAVCA  ;  P69485, VP2_CAVCI  ;  P0AAB3, WZB_ECO57  ;
DR   P0AAB2, WZB_ECOLI  ;  Q8Z5G5, WZB_SALTI  ;  Q9F7B2, WZB_SALTY  ;
DR   Q9ZVN4, Y1500_ARATH;  Q55535, Y328_SYNY3 ;  P40289, Y669_CUPNH ;
DR   O35016, YFKJ_BACSU ;  P34337, YK13_CAEEL ;  P42083, YKCA_CAEEL ;
DR   Q9UUF3, YNF3_SCHPO ;  P15273, YOPH_YEREN ;  P08538, YOPH_YERPS ;
DR   Q48451, YOR5_KLEPN ;  P39155, YWLE_BACSU ;  P96717, YWQE_BACSU ;
//
ID   3.1.3.49
DE   [Pyruvate kinase]-phosphatase.
CA   [Pyruvate kinase] phosphate + H(2)O = [pyruvate kinase] + phosphate.
CC   -!- Simultaneously dephosphorylates and activates EC 2.7.1.40 which has
CC       been inactivated by protein kinase.
//
ID   3.1.3.50
DE   Sorbitol-6-phosphatase.
CA   Sorbitol 6-phosphate + H(2)O = sorbitol + phosphate.
CC   -!- Acts, very slowly, on hexose 6-phosphates.
//
ID   3.1.3.51
DE   Dolichyl-phosphatase.
AN   Dolichol phosphate phosphatase.
CA   Dolichyl phosphate + H(2)O = dolichol + phosphate.
//
ID   3.1.3.52
DE   [3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]-
DE   phosphatase.
AN   Branched-chain oxo-acid dehydrogenase phosphatase.
CA   [3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]
CA   phosphate + H(2)O = [3-methyl-2-oxobutanoate dehydrogenase
CA   (2-methylpropanoyl-transferring)] + phosphate.
CC   -!- A mitochondrial enzyme associated with the 3-methyl-2-oxobutanoate
CC       dehydrogenase complex.
CC   -!- Simultaneously dephosphorylates and activates EC 1.2.4.4 which has
CC       been inactivated by phosphorylation.
//
ID   3.1.3.53
DE   [Myosin-light-chain] phosphatase.
AN   Myosin light-chain kinase phosphatase.
AN   Myosin phosphatase.
CA   [Myosin light-chain] phosphate + H(2)O = [myosin light-chain] +
CA   phosphate.
CC   -!- Composed of three subunits.
CC   -!- The holoenzyme dephosphorylates myosin light chains and EC 2.7.11.31,
CC       but not myosin; the catalytic subunit acts on all three substrates.
DR   Q3SWW9, PP1B_BOVIN ;  Q8MJ47, PP1B_CANFA ;  P62207, PP1B_CHICK ;
DR   P62140, PP1B_HUMAN ;  P62141, PP1B_MOUSE ;  P61292, PP1B_PIG   ;
DR   Q5R740, PP1B_PONAB ;  P62143, PP1B_RABIT ;  P62142, PP1B_RAT   ;
//
ID   3.1.3.54
DE   Fructose-2,6-bisphosphate 6-phosphatase.
CA   Beta-D-fructose 2,6-bisphosphate + H(2)O = beta-D-fructofuranose
CA   2-phosphate + phosphate.
CC   -!- Cf. EC 3.1.3.46.
//
ID   3.1.3.55
DE   Caldesmon-phosphatase.
CA   [Caldesmon] phosphate + H(2)O = [caldesmon] + phosphate.
CC   -!- Dephosphorylation activates the calmodulin- and actin-binding ability
CC       of caldesmon.
//
ID   3.1.3.56
DE   Inositol-polyphosphate 5-phosphatase.
AN   5PTase.
AN   D-myo-inositol 1,4,5-triphosphate 5-phosphatase.
AN   D-myo-inositol 1,4,5-trisphosphate 5-phosphatase.
AN   D-myo-inositol(1,4,5)/(1,3,4,5)-polyphosphate 5-phosphatase.
AN   Inosine triphosphatase.
AN   Inositol 1,4,5-trisphosphate phosphatase.
AN   Inositol phosphate 5-phosphomonoesterase.
AN   Inositol polyphosphate-5-phosphatase.
AN   Inositol trisphosphate phosphomonoesterase.
AN   Inositol-1,4,5-trisphosphate 5-phosphatase.
AN   Inositol-1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase.
AN   Ins(1,4,5)P(3) 5-phosphatase.
AN   InsP(3)/Ins(1,3,4,5)P(4) 5-phosphatase.
AN   L-myo-inositol 1,4,5-trisphosphate-monoesterase.
AN   Myo-inositol-1,4,5-trisphosphate 5-phosphatase.
AN   Type I inositol-polyphosphate phosphatase.
CA   (1) D-myo-inositol 1,4,5-trisphosphate + H(2)O = myo-inositol 1,4-
CA   bisphosphate + phosphate.
CA   (2) 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H(2)O = 1D-myo-inositol
CA   1,3,4-trisphosphate + phosphate.
CC   -!- This enzyme is distinguished from the family of enzymes classified
CC       under EC 3.1.3.36 by its inability to dephosphorylate inositol
CC       lipids.
DR   Q17848, I5P1_CAEEL ;  Q29467, I5P1_CANFA ;  Q14642, I5P1_HUMAN ;
DR   Q9BT40, INP5K_HUMAN;  Q8C5L6, INP5K_MOUSE;  Q84MA2, IP5P1_ARATH;
DR   Q9FUR2, IP5P2_ARATH;  Q9LR47, IP5P3_ARATH;  Q5EAF2, IP5PB_ARATH;
DR   O80560, IP5PC_ARATH;  Q9SYK4, IP5PD_ARATH;  Q15735, PI5PA_HUMAN;
DR   P59644, PI5PA_MOUSE;  Q9JMC1, PI5PA_RAT  ;
//
ID   3.1.3.57
DE   Inositol-1,4-bisphosphate 1-phosphatase.
AN   Inositol polyphosphate 1-phosphatase.
CA   1D-myo-inositol 1,4-bisphosphate + H(2)O = 1D-myo-inositol 4-phosphate +
CA   phosphate.
CC   -!- Acts on inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate
CC       (forming inositol 3,4-bisphosphate) with similar V(max) for both
CC       substrates, but with a 5 times higher affinity for the bisphosphate.
CC   -!- Does not act on inositol 1-phosphate, inositol 1,4,5-trisphosphate or
CC       inositol 1,3,4,5-tetrakisphosphate.
PR   PROSITE; PDOC00547;
DR   Q42546, DPNP1_ARATH;  O49623, DPNP2_ARATH;  Q8GY63, DPNP3_ARATH;
DR   Q84VY5, DPNP4_ARATH;  Q55F34, DPNP_DICDI ;  P21327, INPP_BOVIN ;
DR   P49441, INPP_HUMAN ;  P49442, INPP_MOUSE ;
//
ID   3.1.3.58
DE   Sugar-terminal-phosphatase.
AN   Xylitol-5-phosphatase.
CA   D-glucose 6-phosphate + H(2)O = D-glucose + phosphate.
CC   -!- Acts on sugars and polyols phosphorylated on the terminal carbon,
CC       with a preference for sugars with a D-erythro-configuration, e.g.
CC       good substrates are glucose 6-phosphate, mannose 6-phosphate,
CC       6-phosphogluconate, erythrose 4-phosphate and xylitol 5-phosphate.
//
ID   3.1.3.59
DE   Alkylacetylglycerophosphatase.
CA   1-alkyl-2-acetyl-sn-glycero-3-phosphate + H(2)O = 1-alkyl-2-acetyl-
CA   sn-glycerol + phosphate.
CC   -!- Involved in the biosynthesis of thrombocyte activating factor in
CC       animal tissues.
//
ID   3.1.3.60
DE   Phosphoenolpyruvate phosphatase.
CA   Phosphoenolpyruvate + H(2)O = pyruvate + phosphate.
CC   -!- Also acts, more slowly, on a wide range of other monophosphates.
//
ID   3.1.3.61
DE   Deleted entry.
//
ID   3.1.3.62
DE   Multiple inositol-polyphosphate phosphatase.
AN   Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase.
AN   Inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase.
AN   Inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase.
AN   Inositol tetrakisphosphate phosphomonoesterase.
AN   Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase.
AN   MIPP.
CA   Myo-inositol hexakisphosphate + H(2)O = myo-inositol pentakisphosphate
CA   (mixed isomers) + phosphate.
CC   -!- Also acts on Ins(1,3,4,5)P(4) to yield Ins(1,4,5)P(3).
DR   Q9UNW1, MINP1_HUMAN;  Q9Z2L6, MINP1_MOUSE;  Q5R890, MINP1_PONAB;
DR   O35217, MINP1_RAT  ;
//
ID   3.1.3.63
DE   2-carboxy-D-arabinitol-1-phosphatase.
CA   2-carboxy-D-arabinitol 1-phosphate + H(2)O = 2-carboxy-D-arabinitol +
CA   phosphate.
//
ID   3.1.3.64
DE   Phosphatidylinositol-3-phosphatase.
AN   D-myo-inositol-1,3-bisphosphate 3-phosphohydrolase.
AN   Inositol 1,3-bisphosphate phosphatase.
AN   Inositol-1,3-bisphosphate 3-phosphatase.
AN   Inositol-polyphosphate 3-phosphatase.
AN   Phosphatidyl-3-phosphate 3-phosphohydrolase.
CA   1-phosphatidyl-1D-myo-inositol 3-phosphate + H(2)O = 1-phosphatidyl-
CA   1D-myo-inositol + phosphate.
CC   -!- This enzyme still works when the 2,3-bis(acyloxy)propyl group is
CC       removed, i.e., it hydrolyzes Ins(1,3)P(2) to Ins-1-P.
CC   -!- Formerly EC 3.1.3.65.
DR   A6QLT4, MTM1_BOVIN ;  Q13496, MTM1_HUMAN ;  Q9Z2C5, MTM1_MOUSE ;
DR   Q5R9S3, MTM1_PONAB ;  Q6AXQ4, MTM1_RAT   ;  Q52KU6, MTM1_XENLA ;
DR   Q5EB32, MTM1_XENTR ;  O13819, YMR1_SCHPO ;  P47147, YMR1_YEAST ;
//
ID   3.1.3.65
DE   Transferred entry: 3.1.3.64.
//
ID   3.1.3.66
DE   Phosphatidylinositol-3,4-bisphosphate 4-phosphatase.
AN   D-myo-inositol-3,4-bisphosphate 4-phosphohydrolase.
AN   Inositol polyphosphate 4-phosphatase.
AN   Inositol polyphosphate 4-phosphatase type II.
AN   Inositol-3,4-bisphosphate 4-phosphatase.
AN   Phosphoinositide 4-phosphatase.
CA   1-phosphatidyl-myo-inositol 3,4-bisphosphate + H(2)O = 1-phosphatidyl-
CA   1D-myo-inositol 3-phosphate + phosphate.
CC   -!- Magnesium-independent.
CC   -!- This enzyme still works when the 2,3-bis(acyloxy)propyl group is
CC       removed, i.e., it hydrolyzes Ins(1,3,4)P(3) to Ins(1,3)P(2).
CC   -!- It also converts Ins(3,4)P(2) into Ins-3-P.
DR   Q96PE3, INP4A_HUMAN;  Q9EPW0, INP4A_MOUSE;  Q62784, INP4A_RAT  ;
DR   O15327, INP4B_HUMAN;  Q4R4D7, INP4B_MACFA;  Q6P1Y8, INP4B_MOUSE;
DR   Q5RA60, INP4B_PONAB;  Q9QWG5, INP4B_RAT  ;
//
ID   3.1.3.67
DE   Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase.
AN   Phosphatidylinositol-3,4,5-trisphosphate 3-phosphohydrolase.
CA   Phosphatidylinositol 3,4,5-trisphosphate + H(2)O = phosphatidylinositol
CA   4,5-bisphosphate + phosphate.
CF   Magnesium.
CC   -!- Does not dephosphorylate inositol 4,5-bisphosphate.
CC   -!- This enzyme still works when the 2,3-bis(acyloxy)propyl group is
CC       removed, i.e., it hydrolyzes Ins(1,3,4,5)P(4) to Ins(1,4,5)P(3).
DR   Q54JL7, CNRN_DICDI ;  P60483, PTEN_CANFA ;  Q8T9S7, PTEN_DICDI ;
DR   P60484, PTEN_HUMAN ;  O08586, PTEN_MOUSE ;  O94526, PTEN_SCHPO ;
DR   Q9PUT6, PTEN_XENLA ;  P53916, TEP1_YEAST ;  Q6XPS3, TPTE2_HUMAN;
DR   Q4R6N0, TPTE2_MACFA;
//
ID   3.1.3.68
DE   2-deoxyglucose-6-phosphatase.
AN   2-deoxyglucose-6-phosphate phosphatase.
CA   2-deoxy-D-glucose 6-phosphate + H(2)O = 2-deoxy-D-glucose + phosphate.
CC   -!- Also active toward fructose 1-phosphate.
DR   P38774, DOG1_YEAST ;  P38773, DOG2_YEAST ;
//
ID   3.1.3.69
DE   Glucosylglycerol 3-phosphatase.
CA   2-(beta-D-glucosyl)-sn-glycerol-3-phosphate + H(2)O = 2-(beta-D-
CA   glucosyl)-sn-glycerol + phosphate.
CC   -!- Acts with EC 2.4.1.213 to form glucosylglycerol, an osmolyte that
CC       endows cyanobacteria with resistance to salt.
DR   Q55034, STPA_SYNY3 ;
//
ID   3.1.3.70
DE   Mannosyl-3-phosphoglycerate phosphatase.
CA   2(alpha-D-mannosyl)-3-phosphoglycerate + H(2)O = 2(alpha-D-mannosyl)-D-
CA   glycerate + phosphate.
CF   Magnesium.
CC   -!- The enzyme from Pyrococcus horikoshii is specific for alpha-D-
CC       mannosyl-3-phosphoglycerate and forms part of the pathway for the
CC       synthesis of mannosylglycerate.
DR   Q9YDM7, MPGP_AERPE ;  A7ZN77, MPGP_ECO24 ;  B7USW8, MPGP_ECO27 ;
DR   B7MCL0, MPGP_ECO45 ;  B7L8W6, MPGP_ECO55 ;  Q8XB99, MPGP_ECO57 ;
DR   B5YSI4, MPGP_ECO5E ;  B7NRC7, MPGP_ECO7I ;  B7MWE2, MPGP_ECO81 ;
DR   B7M394, MPGP_ECO8A ;  C4ZQM8, MPGP_ECOBW ;  B1X6A8, MPGP_ECODH ;
DR   A1ACA3, MPGP_ECOK1 ;  Q0TGP0, MPGP_ECOL5 ;  P59286, MPGP_ECOL6 ;
DR   B1IZV5, MPGP_ECOLC ;  P76329, MPGP_ECOLI ;  B7NBU7, MPGP_ECOLU ;
DR   B6I101, MPGP_ECOSE ;  B1LQQ4, MPGP_ECOSM ;  Q1RAI5, MPGP_ECOUT ;
DR   Q9UZC0, MPGP_PYRAB ;  Q8U381, MPGP_PYRFU ;  O58690, MPGP_PYRHO ;
DR   Q57N15, MPGP_SALCH ;  Q5PLI3, MPGP_SALPA ;  P65418, MPGP_SALTI ;
DR   P65417, MPGP_SALTY ;  B2TXJ0, MPGP_SHIB3 ;  Q322Q3, MPGP_SHIBS ;
DR   Q32HI9, MPGP_SHIDS ;  Q3Z0N4, MPGP_SHISS ;
//
ID   3.1.3.71
DE   2-phosphosulfolactate phosphatase.
AN   (2R)-phosphosulfolactate phosphohydrolase.
AN   ComB phosphatase.
CA   (2R)-2-phospho-3-sulfolactate + H(2)O = (2R)-3-sulfolactate + phosphate.
CF   Magnesium.
CC   -!- The enzyme from Methanococcus jannaschii acts on both stereoisoimers
CC       of the substrate and also hydrolyzes a number of phosphate monoesters
CC       of (S)-2-hydroxycarboxylic acids, including 2-phosphomalate,
CC       2-phospholactate and 2-phosphoglycolate.
CC   -!- This enzyme can also hydrolyze phosphate monoesters of (R)-2-
CC       hydroxycarboxylic acids such as (S)-2-phospho-3-sulfolactate and (R)-
CC       2-phosphomalate, which, presumably, bind to the enzyme in opposite
CC       orientations.
DR   Q3MFW5, COMB_ANAVT ;  O06738, COMB_BACSU ;  A4XFZ6, COMB_CALS8 ;
DR   Q3AD96, COMB_CARHZ ;  Q97E82, COMB_CLOAB ;  A7FPH4, COMB_CLOB1 ;
DR   C3KWA9, COMB_CLOB6 ;  A6LPF0, COMB_CLOB8 ;  B2UX99, COMB_CLOBA ;
DR   B2THU3, COMB_CLOBB ;  C1FNF9, COMB_CLOBJ ;  B1IH09, COMB_CLOBK ;
DR   A7GJE7, COMB_CLOBL ;  B1KTF5, COMB_CLOBM ;  B9DY39, COMB_CLOK1 ;
DR   A5N4H7, COMB_CLOK5 ;  A0Q380, COMB_CLONN ;  Q0TM95, COMB_CLOP1 ;
DR   Q8XHC9, COMB_CLOPE ;  Q0SPZ8, COMB_CLOPS ;  Q899J5, COMB_CLOTE ;
DR   B8HW27, COMB_CYAP4 ;  B7K825, COMB_CYAP7 ;  B7JUJ9, COMB_CYAP8 ;
DR   C1D1F5, COMB_DEIDV ;  Q1IYS0, COMB_DEIGD ;  Q9RUI6, COMB_DEIRA ;
DR   Q7NCK4, COMB_GLOVI ;  Q58540, COMB_METJA ;  O27250, COMB_METTH ;
DR   B0JV88, COMB_MICAN ;  B2IVU1, COMB_NOSP7 ;  Q8YTZ5, COMB_NOSS1 ;
DR   A2C172, COMB_PROM1 ;  A2CAX3, COMB_PROM3 ;  Q7VBP6, COMB_PROMA ;
DR   Q7V8F6, COMB_PROMM ;  Q46LT5, COMB_PROMT ;  Q9F3E6, COMB_STRCO ;
DR   Q67NP7, COMB_SYMTH ;  Q2JWJ9, COMB_SYNJA ;  Q2JPJ7, COMB_SYNJB ;
DR   B1XQ41, COMB_SYNP2 ;  A5GKJ5, COMB_SYNPW ;  Q7U7H6, COMB_SYNPX ;
DR   A5GT49, COMB_SYNR3 ;  Q0I9X0, COMB_SYNS3 ;  Q3AXB9, COMB_SYNS9 ;
DR   Q3AKJ4, COMB_SYNSC ;  P73849, COMB_SYNY3 ;  Q9HIA9, COMB_THEAC ;
DR   Q8DLS5, COMB_THEEB ;  A8F5X7, COMB_THELT ;  Q9WZQ4, COMB_THEMA ;
DR   A5IIY7, COMB_THEP1 ;  Q72IQ9, COMB_THET2 ;  Q5SID6, COMB_THET8 ;
DR   Q8R8M3, COMB_THETN ;  Q97CK6, COMB_THEVO ;  Q116L2, COMB_TRIEI ;
//
ID   3.1.3.72
DE   5-phytase.
CA   Myo-inositol hexakisphosphate + H(2)O = 1L-myo-inositol 1,2,3,4,6-
CA   pentakisphosphate + phosphate.
CC   -!- The enzyme attacks the product of the above reaction more slowly to
CC       yield Ins(1,2,3)P(3).
//
ID   3.1.3.73
DE   Adenosylcobalamin/alpha-ribazole phosphatase.
AN   Adenosylcobalamin phosphatase.
AN   Alpha-ribazole phosphatase.
CA   (1) Adenosylcobalamin 5'-phosphate + H(2)O = coenzyme B12 + phosphate.
CA   (2) Alpha-ribazole 5'-phosphate + H(2)O = alpha-ribazole + phosphate.
CC   -!- This enzyme catalyzes the last step in the anaerobic (early cobalt
CC       insertion) pathway of adenosylcobalamin biosynthesis, characterized
CC       in Salmonella enterica.
CC   -!- It also participates in a salvage pathway that recycles cobinamide
CC       into adenosylcobalamin.
DR   P52086, COBC_ECOLI ;  P58652, COBC_SALTI ;  P39701, COBC_SALTY ;
//
ID   3.1.3.74
DE   Pyridoxal phosphatase.
AN   PLP phosphatase.
AN   PNP phosphatase.
AN   Vitamin B(6) (pyridoxine) phosphatase.
AN   Vitamin B(6)-phosphate phosphatase.
AN   Vitamin B6 (pyridoxine) phosphatase.
AN   Vitamin B6-phosphate phosphatase.
CA   Pyridoxal 5'-phosphate + H(2)O = pyridoxal + phosphate.
CF   Magnesium.
CC   -!- Specific for phosphorylated vitamin B(6) compounds: it acts not only
CC       on pyridoxal phosphate (PLP), but also on pyridoxine phosphate (PNP),
CC       pyridoxamine phosphate (PMP), 4-pyridoxic acid phosphate and
CC       4-deoxypyridoxine phosphate.
CC   -!- This reaction can also be carried out by EC 3.1.3.1 and EC 3.1.3.2,
CC       but these enzymes have very broad substrate specificities.
DR   Q2KI06, PHOP2_BOVIN;  Q8TCD6, PHOP2_HUMAN;  Q9D9M5, PHOP2_MOUSE;
DR   Q66HC4, PHOP2_RAT  ;  Q3ZBF9, PLPP_BOVIN ;  Q96GD0, PLPP_HUMAN ;
DR   P60487, PLPP_MOUSE ;  Q8VD52, PLPP_RAT   ;
//
ID   3.1.3.75
DE   Phosphoethanolamine/phosphocholine phosphatase.
AN   3X11A.
AN   PHOSPHO1.
CA   (1) O-phosphoethanolamine + H(2)O = ethanolamine + phosphate.
CA   (2) Phosphocholine + H(2)O = choline + phosphate.
CF   Cobalt or manganese or magnesium.
CC   -!- The enzyme is highly specific for phosphoethanolamine and
CC       phosphocholine.
DR   O73884, PHOP1_CHICK;  Q8TCT1, PHOP1_HUMAN;  Q8R2H9, PHOP1_MOUSE;
//
ID   3.1.3.76
DE   Lipid-phosphate phosphatase.
AN   Dihydroxy fatty acid phosphatase.
AN   Hydroxy fatty acid phosphatase.
AN   Hydroxy lipid phosphatase.
AN   Soluble epoxide hydrolase.
CA   (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H(2)O = (9S,10S)-
CA   9,10-dihydroxyoctadecanoate + phosphate.
CF   Magnesium.
CC   -!- The enzyme from mammals is a bifunctional enzyme: the N-terminal
CC       domain exhibits lipid-phosphate-phosphatase activity and the
CC       C-terminal domain has the activity of EC 3.3.2.10.
CC   -!- The best substrates for this enzyme are 10-hydroxy-9-
CC       (phosphonooxy)octadecanoates, with the threo- form being a better
CC       substrate than the erythro- form.
CC   -!- The phosphatase activity is not found in plant EC 3.3.2.10 or in
CC       mammalian EC 3.3.2.9.
//
ID   3.1.3.77
DE   Acireductone synthase.
AN   E-1 enolase-phosphatase.
CA   5-(methylthio)-2,3-dioxopentyl phosphate + H(2)O = 1,2-dihydroxy-5-
CA   (methylthio)pent-1-en-3-one + phosphate.
CC   -!- This bifunctional enzyme first enolizes the substrate to form the
CC       intermediate 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate,
CC       which is then dephosphorylated to form the acireductone 1,2-
CC       dihydroxy-5-(methylthio)pent-1-en-3-one.
CC   -!- The acireductone represents a branch point in the methione salvage
CC       pathway as it is used in the formation of formate, CO and
CC       3-(methylthio)propanoate by EC 1.13.11.53 and of formate and
CC       4-methylthio-2-oxobutanoate either by a spontaneous reaction under
CC       aerobic conditions or by EC 1.13.11.54.
DR   C4WUT0, ENOPH_ACYPI;  Q17Q32, ENOPH_AEDAE;  Q7Q9C0, ENOPH_ANOGA;
DR   Q753F5, ENOPH_ASHGO;  A6SRT0, ENOPH_BOTFB;  Q0VD27, ENOPH_BOVIN;
DR   C3XR70, ENOPH_BRAFL;  A8Y461, ENOPH_CAEBR;  Q21012, ENOPH_CAEEL;
DR   Q5AM80, ENOPH_CANAL;  C4YJE1, ENOPH_CANAW;  B9WAM8, ENOPH_CANDC;
DR   Q6FLR5, ENOPH_CANGA;  C5M5Z6, ENOPH_CANTT;  Q2H683, ENOPH_CHAGB;
DR   C4Y3W1, ENOPH_CLAL4;  B0WQG0, ENOPH_CULQU;  Q6GMI7, ENOPH_DANRE;
DR   Q6BXC7, ENOPH_DEBHA;  Q55FM6, ENOPH_DICDI;  B3M173, ENOPH_DROAN;
DR   B3P2A7, ENOPH_DROER;  B4JSP3, ENOPH_DROGR;  Q9VN95, ENOPH_DROME;
DR   B4KCL9, ENOPH_DROMO;  B4GFE6, ENOPH_DROPE;  Q296B0, ENOPH_DROPS;
DR   B4I3X6, ENOPH_DROSE;  B4QW91, ENOPH_DROSI;  B4M4X4, ENOPH_DROVI;
DR   B4NI64, ENOPH_DROWI;  B4PV71, ENOPH_DROYA;  Q9UHY7, ENOPH_HUMAN;
DR   Q6CM87, ENOPH_KLULA;  C5DDS4, ENOPH_LACTC;  A5DUA7, ENOPH_LODEL;
DR   A4RM80, ENOPH_MAGO7;  A9V2Y9, ENOPH_MONBE;  Q8BGB7, ENOPH_MOUSE;
DR   D2UYP1, ENOPH_NAEGR;  C7Z9X4, ENOPH_NECH7;  Q7SBS7, ENOPH_NEUCR;
DR   A5DIR2, ENOPH_PICGU;  C4R1T9, ENOPH_PICPG;  A3LRM2, ENOPH_PICST;
DR   B2AWZ9, ENOPH_PODAN;  Q5PPH0, ENOPH_RAT  ;  B5X2D1, ENOPH_SALSA;
DR   B6JXU1, ENOPH_SCHJY;  Q9P6Q2, ENOPH_SCHPO;  A7E3Z4, ENOPH_SCLS1;
DR   D1ZPB8, ENOPH_SORMK;  A7TN25, ENOPH_VANPO;  C9SUS0, ENOPH_VERA1;
DR   Q569R5, ENOPH_XENLA;  Q28C69, ENOPH_XENTR;  Q6C8V1, ENOPH_YARLI;
DR   B3LRX9, ENOPH_YEAS1;  C7GKE1, ENOPH_YEAS2;  B5VH97, ENOPH_YEAS6;
DR   A6ZQR2, ENOPH_YEAS7;  P32626, ENOPH_YEAST;  C5DXI0, ENOPH_ZYGRC;
DR   E0CSI1, MTBC1_VITVI;  E0CTF3, MTBC2_VITVI;  Q9FN41, MTBC_ARATH ;
DR   B4G0F3, MTBC_MAIZE ;  B8BKI7, MTBC_ORYSI ;  Q2R483, MTBC_ORYSJ ;
DR   A9RBS1, MTBC_PHYPA ;  B9N1F9, MTBC_POPTR ;  B9SQI7, MTBC_RICCO ;
DR   C6JS30, MTBC_SORBI ;  A5FUG6, MTNC_ACICJ ;  Q0VPK3, MTNC_ALCBS ;
DR   O67786, MTNC_AQUAE ;  C1DHH2, MTNC_AZOVD ;  A5EES8, MTNC_BRASB ;
DR   A8ANI1, MTNC_CITK8 ;  A4W7Z3, MTNC_ENT38 ;  P0C8L5, MTNC_ENTAE ;
DR   A7MK11, MTNC_ENTS8 ;  Q3ZUZ9, MTNC_ENTSA ;  Q6D1G2, MTNC_ERWCT ;
DR   B2VIR2, MTNC_ERWT9 ;  Q0RQV6, MTNC_FRAAA ;  A9H8G7, MTNC_GLUDA ;
DR   Q5FRJ1, MTNC_GLUOX ;  Q0BPT7, MTNC_GRABC ;  Q2SKZ0, MTNC_HAHCH ;
DR   B4U605, MTNC_HYDS0 ;  Q48389, MTNC_KLEOX ;  B5XZU3, MTNC_KLEP3 ;
DR   A6T673, MTNC_KLEP7 ;  B0SFG5, MTNC_LEPBA ;  Q04QY0, MTNC_LEPBJ ;
DR   Q04Z87, MTNC_LEPBL ;  B0SP16, MTNC_LEPBP ;  Q72NW0, MTNC_LEPIC ;
DR   Q8F7L5, MTNC_LEPIN ;  A1TZ36, MTNC_MARAV ;  Q60AP9, MTNC_METCA ;
DR   Q5YQZ4, MTNC_NOCFA ;  A7HU88, MTNC_PARL1 ;  C6DCZ3, MTNC_PECCP ;
DR   C0QPL9, MTNC_PERMH ;  A2CBQ3, MTNC_PROM3 ;  Q7V8Y7, MTNC_PROMM ;
DR   Q48KM6, MTNC_PSE14 ;  A6V7A6, MTNC_PSEA7 ;  B7UV36, MTNC_PSEA8 ;
DR   Q02KH5, MTNC_PSEAB ;  Q9I340, MTNC_PSEAE ;  Q3KFI7, MTNC_PSEPF ;
DR   Q884P1, MTNC_PSESM ;  Q4ZVB8, MTNC_PSEU2 ;  A4FFQ6, MTNC_SACEN ;
DR   A8GAA9, MTNC_SERP5 ;  A1S1N0, MTNC_SHEAM ;  B8E3J4, MTNC_SHEB2 ;
DR   A3DAG6, MTNC_SHEB5 ;  A6WHG9, MTNC_SHEB8 ;  A9KV69, MTNC_SHEB9 ;
DR   Q12T52, MTNC_SHEDO ;  Q07W23, MTNC_SHEFN ;  B0TM50, MTNC_SHEHH ;
DR   A3QJI9, MTNC_SHELP ;  Q8EKK8, MTNC_SHEON ;  A8HAA3, MTNC_SHEPA ;
DR   A4Y1H2, MTNC_SHEPC ;  B8CGX4, MTNC_SHEPW ;  A0KRB5, MTNC_SHESA ;
DR   A8G1T3, MTNC_SHESH ;  Q0HP46, MTNC_SHESM ;  Q0I0L4, MTNC_SHESR ;
DR   A1RQ67, MTNC_SHESW ;  B1KPZ1, MTNC_SHEWM ;  A9FCY5, MTNC_SORC5 ;
DR   Q828K9, MTNC_STRAW ;  B4STR0, MTNC_STRM5 ;  B2FPP2, MTNC_STRMK ;
DR   B2V7G7, MTNC_SULSY ;  Q31LP5, MTNC_SYNE7 ;  B1XPT1, MTNC_SYNP2 ;
DR   Q5N078, MTNC_SYNP6 ;  A5GJ48, MTNC_SYNPW ;  Q7U4U9, MTNC_SYNPX ;
DR   A5GR42, MTNC_SYNR3 ;  Q3AWF3, MTNC_SYNS9 ;  Q3AMB9, MTNC_SYNSC ;
DR   B8GMB3, MTNC_THISH ;  Q8PLG2, MTNC_XANAC ;  Q3BUE8, MTNC_XANC5 ;
DR   Q4UU49, MTNC_XANC8 ;  B0RSM3, MTNC_XANCB ;  Q8P9N5, MTNC_XANCP ;
DR   Q2P3W6, MTNC_XANOM ;  B2SM84, MTNC_XANOP ;  Q5H0Y0, MTNC_XANOR ;
DR   A7IJF6, MTNC_XANP2 ;  B2I5X4, MTNC_XYLF2 ;  Q9PBD3, MTNC_XYLFA ;
DR   B0U3A6, MTNC_XYLFM ;  Q87C36, MTNC_XYLFT ;  A1JP11, MTNC_YERE8 ;
DR   A7FLL3, MTNC_YERP3 ;  B2K631, MTNC_YERPB ;  A9R2Z7, MTNC_YERPG ;
DR   A4TPN1, MTNC_YERPP ;  Q66E18, MTNC_YERPS ;  B1JIK5, MTNC_YERPY ;
//
ID   3.1.3.78
DE   Phosphatidylinositol-4,5-bisphosphate 4-phosphatase.
AN   PtdIns-4,5-P(2) 4-phosphatase.
CA   1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-
CA   1D-myo-inositol 5-phosphate + phosphate.
CC   -!- Two pathways exist in mammalian cells to degrade 1-phosphatidyl-
CC       1D-myo-inositol 4,5-bisphosphate (PtdIns(4,5)P(2)).
CC   -!- One is catalyzed by this enzyme and the other by EC 3.1.3.36, where
CC       the product is PtdIns4P.
CC   -!- The enzyme from human is specific for PtdIns(4,5)P(2) as substrate,
CC       as it cannot use PtdIns(3,4,5)P(3), PtdIns(3,4)P(2), PtdIns(3,5)P(2),
CC       PtdIns5P, PtdIns4P or PtdIns3P.
CC   -!- In humans, the enzyme is localized to late endosomal/lysosomal
CC       membranes.
CC   -!- It can control nuclear levels of PtdIns(5)P and thereby control p53-
CC       dependent apoptosis.
CC   -!- Formerly EC 3.1.3.n3.
DR   Q07566, IPGD_SHIFL ;  Q55286, IPGD_SHISO ;  Q3SZ48, TM55A_BOVIN;
DR   Q8N4L2, TM55A_HUMAN;  Q9CZX7, TM55A_MOUSE;  Q4V888, TM55A_RAT  ;
DR   Q5EAU3, TM55A_XENLA;  Q6DIE4, TM55A_XENTR;  Q86T03, TM55B_HUMAN;
DR   Q4R6W2, TM55B_MACFA;  Q3TWL2, TM55B_MOUSE;  Q5PPM8, TM55B_RAT  ;
DR   Q5XKA6, TM55B_XENLA;
//
ID   3.1.3.79
DE   Mannosylfructose-phosphate phosphatase.
AN   Mannosylfructose-6-phosphate phosphatase.
AN   MFPP.
CA   Beta-D-fructofuranosyl-alpha-D-mannopyranoside 6(F)-phosphate + H(2)O =
CA   alpha-D-fructofuranosyl-alpha-D-mannopyranoside + phosphate.
CF   Magnesium.
CC   -!- Mannosylfructose is the major endogenous osmolyte produced by several
CC       alpha-proteobacteria in response to osmotic stress and is synthesized
CC       by the sequential action of EC 2.4.1.246 followed by this enzyme.
CC   -!- While mannosylfructose 6-phosphate is the physiological substrate,
CC       the enzyme can use sucrose 6-phosphate very efficiently.
CC   -!- The F in mannosylfructose 6(F)-phosphate is used to indicate that the
CC       fructose residue of sucrose carries the substituent.
DR   A9CK30, MFPP_AGRT5 ;
//
ID   3.1.3.80
DE   2,3-bisphosphoglycerate 3-phosphatase.
AN   2,3-BPG 3-phosphatase.
CA   2,3-bisphospho-D-glycerate + H(2)O = 2-phospho-D-glycerate + phosphate.
CC   -!- This reaction is a shortcut in the Rapoport-Luebering shunt.
CC   -!- It bypasses the reactions of EC 3.1.3.13/EC 5.4.2.1 and directly
CC       forms 2-phospho-Dglycerate by removing the 3-phospho-group of 2,3-
CC       diphospho-Dglycerate.
CC   -!- The MIPP1 protein also catalyzes the reaction of EC 3.1.3.62.
PR   PROSITE; PDOC00538;
//
ID   3.1.3.81
DE   Diacylglycerol diphosphate phosphatase.
AN   DGPP phosphatase.
AN   DGPP phosphohydrolase.
AN   Pyrophosphate phosphatase.
CA   1,2-diacyl-sn-glycerol 3-diphosphate + H(2)O = 1,2-diacyl-sn-glycerol
CA   3-phosphate + phosphate.
CC   -!- The bifunctional enzyme catalyzes the dephosphorylation of
CC       diacylglycerol diphosphate to phosphatidate and the subsequent
CC       dephosphorylation of phosphatidate to diacylglycerol (cf.
CC       EC 3.1.3.4).
CC   -!- It regulates intracellular levels of diacylglycerol diphosphate and
CC       phosphatidate, phospholipid molecules believed to play a signaling
CC       role in stress response.
CC   -!- The phosphatase activity of the bifunctional enzyme is Mg(2+)-
CC       independent and N-ethylmaleimide-insensitive and is distinct from the
CC       Mg(2+)-dependent and N-ethylmaleimide-sensitive enzyme EC 3.1.3.4.
CC   -!- The diacylglycerol pyrophosphate phosphatase activity in
CC       Saccharomyces cerevisiae is induced by zinc depletion, by inositol
CC       supplementation, and when cells enter the stationary phase.
//
ID   3.1.3.82
DE   D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase.
CA   D-glycero-beta-D-manno-heptose 1,7-bisphosphate + H(2)O = D-glycero-beta-
CA   D-manno-heptose 1-phosphate + phosphate.
CC   -!- The enzyme is involved in biosynthesis of ADP-L-glycero-beta-D-manno-
CC       heptose, which is utilized for assembly of the lipopolysaccharide
CC       inner core in Gram-negative bacteria.
CC   -!- In vitro the catalytic efficiency with the beta-anomer is 100-200-
CC       fold higher than with the alpha-anomer.
//
ID   3.1.3.83
DE   D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase.
CA   D-glycero-alpha-D-manno-heptose-1,7-bisphosphate + H(2)O =  D-glycero-
CA   alpha-D-manno-heptose-1-phosphate + phosphate.
CC   -!- The enzyme is involved in biosynthesis of GDP-D-glycero-alpha-D-
CC       manno-heptose, which is required for assembly of S-layer glycoprotein
CC       in some Gram-positive bacteria.
CC   -!- The in vitro catalytic efficiency of the enzyme from Bacteroides
CC       thetaiotaomicron is 6-fold higher with the alpha-anomer than with the
CC       beta-anomer.
//
ID   3.1.3.84
DE   ADP-ribose 1''-phosphate phosphatase.
AN   Appr1p phosphatase.
CA   ADP-ribose 1''-phosphate + H(2)O = ADP-ribose + phosphate.
CC   -!- The enzyme is highly specific for ADP-ribose 1''-phosphate.
CC   -!- Involved together with EC 3.1.4.37 in the breakdown of adenosine
CC       diphosphate ribose 1'',2''-cyclic phosphate (Appr>p), a by-product of
CC       tRNA splicing.
CC   -!- Formerly EC 3.1.3.n2.
DR   A6QXU0, POA1_AJECN ;  A1CNH7, POA1_ASPCL ;  Q4WRE8, POA1_ASPFU ;
DR   Q2UQY2, POA1_ASPOR ;  Q5A1V3, POA1_CANAL ;  Q6FXN3, POA1_CANGA ;
DR   Q2GV19, POA1_CHAGB ;  Q6BPN4, POA1_DEBHA ;  A5E287, POA1_LODEL ;
DR   A1D1B7, POA1_NEOFI ;  Q0UHC0, POA1_PHANO ;  A5DR03, POA1_PICGU ;
DR   A3LZD1, POA1_PICST ;  A7TJY9, POA1_VANPO ;  Q6CHN5, POA1_YARLI ;
DR   A6ZKW8, POA1_YEAS7 ;  P38218, POA1_YEAST ;  Q04299, YMX7_YEAST ;
//
ID   3.1.3.n1
DE   Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase.
AN   SHIP.
CA   1-phosphatidyl-1D-myo-inositol 3,4,5-triphosphate + H(2)O =
CA   1-phosphatidyl-1D-myo-inositol 3,4-diphosphate + phosphate.
CC   -!- This enzyme hydrolyzes phosphatidylinositol-3,4,5-trisphosphate
CC       (PtdIns(3,4,5)P(3)) to produce PtdIns(3,4)P(2), thereby negatively
CC       regulating the PI3K (phosphoinositide 3-kinase) pathways.
CC   -!- While the SHIP2 isoform is specific for PtdIns(3,4,5)P(3), SHIP1 also
CC       shows activity toward PtdIns(1,3,4,5)P(4).
CC   -!- The enzyme acts as a negative regulator of B-cell antigen receptor
CC       signaling.
CC   -!- Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing
CC       a central role in terminating signal transduction from activating
CC       immune/hematopoietic cell receptor systems.
CC   -!- Acts as a negative regulator of myeloid cell proliferation/survival
CC       and chemotaxis, mast cell degranulation, immune cells homeostasis,
CC       integrin alpha-IIb/beta-3 signaling in platelets and JNK signaling in
CC       B-cells.
CC   -!- Regulates proliferation of osteoclast precursors, macrophage
CC       programming, phagocytosis and activation and is required for
CC       endotoxin tolerance.
CC   -!- Involved in the control of cell-cell junctions, CD32a signaling in
CC       neutrophils and modulation of EGF-induced phospholipase C activity.
CC   -!- Key regulator of neutrophil migration, by governing the formation of
CC       the leading edge and polarization required for chemotaxis.
CC   -!- Modulates FCGR3/CD16-mediated cytotoxicity in NK cells.
CC   -!- Mediates the activin/TGF-beta-induced apoptosis through its Smad-
CC       dependent expression.
CC   -!- May also hydrolyze PtdIns(1,3,4,5)P(4), and could thus affect the
CC       levels of the higher inositol polyphosphates like InsP(6).
DR   Q92835, SHIP1_HUMAN;  Q9ES52, SHIP1_MOUSE;  P97573, SHIP1_RAT  ;
DR   Q6P4S2, SHIP1_XENLA;  O15357, SHIP2_HUMAN;  Q6P549, SHIP2_MOUSE;
DR   Q9WVR3, SHIP2_RAT  ;  Q2I6J1, SHP2A_DANRE;  Q2I6J0, SHP2B_DANRE;
//
ID   3.1.3.n2
DE   Transferred entry: 3.1.3.84.
//
ID   3.1.3.n3
DE   Transferred entry: 3.1.3.78.
//
ID   3.1.3.n4
DE   2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase.
AN   HK-MTPenyl-1-P phosphatase.
CA   2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H(2)O = 1,2-
CA   dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate.
CC   -!- In some species, this reaction and the reaction catalyzed by
CC       EC 5.3.2.n1 are catalyzed by EC 3.1.3.77.
DR   Q65KJ7, MTNBX_BACLD;  A7Z3X5, MTNX_BACA2 ;  C3P746, MTNX_BACAA ;
DR   C3LIA7, MTNX_BACAC ;  A0RI43, MTNX_BACAH ;  Q81MJ1, MTNX_BACAN ;
DR   B7JL17, MTNX_BACC0 ;  Q731R1, MTNX_BACC1 ;  B7IWE9, MTNX_BACC2 ;
DR   C1EQR2, MTNX_BACC3 ;  B7H928, MTNX_BACC4 ;  B7HN15, MTNX_BACC7 ;
DR   A7GS61, MTNX_BACCN ;  B9IWQ0, MTNX_BACCQ ;  Q819E7, MTNX_BACCR ;
DR   Q635P2, MTNX_BACCZ ;  Q6HEC8, MTNX_BACHK ;  A8FCG9, MTNX_BACP2 ;
DR   O31667, MTNX_BACSU ;  A9VFE0, MTNX_BACWK ;  C0ZL41, MTNX_BREBN ;
DR   B1YIY1, MTNX_EXIS2 ;  C4KZ51, MTNX_EXISA ;  Q5L1E1, MTNX_GEOKA ;
DR   A4ILL6, MTNX_GEOTN ;  B1HYT5, MTNX_LYSSC ;  A8YIE1, MTNX_MICAE ;
DR   B0JX47, MTNX_MICAN ;
//
ID   3.1.4.1
DE   Phosphodiesterase I.
AN   5' nucleotide phosphodiesterase/alkaline phosphodiesterase I.
AN   5'-exonuclease.
AN   5'-NPDase.
AN   5'-nucleotide phosphodiesterase.
AN   5'-PDase.
AN   5'-PDE.
AN   5'-phosphodiesterase.
AN   5'NPDE.
AN   Alkaline phosphodiesterase.
AN   Exonuclease I.
AN   Nucleotide pyrophosphatase/phosphodiesterase I.
AN   Oligonucleate 5'-nucleotidohydrolase.
AN   Orthophosphoric diester phosphohydrolase.
AN   PDE I.
AN   Phosphodiesterase.
CA   Hydrolytically removes 5'-nucleotides successively from the 3'-hydroxy
CA   termini of 3'-hydroxy-terminated oligonucleotides.
CC   -!- Hydrolyzes both ribonucleotides and deoxyribonucleotides.
CC   -!- Has low activity toward polynucleotides.
CC   -!- A 3'-phosphate terminus on the substrate inhibits hydrolysis.
DR   P22413, ENPP1_HUMAN;  P06802, ENPP1_MOUSE;  Q924C3, ENPP1_RAT  ;
DR   P15396, ENPP3_BOVIN;  O14638, ENPP3_HUMAN;  Q6DYE8, ENPP3_MOUSE;
DR   Q5R5M5, ENPP3_PONAB;  P97675, ENPP3_RAT  ;  D2HNY3, FAN1_AILME ;
DR   Q1LWH4, FAN1_DANRE ;  Q9Y2M0, FAN1_HUMAN ;  Q69ZT1, FAN1_MOUSE ;
DR   P25353, NPP1_YEAST ;  P39997, NPP2_YEAST ;
//
ID   3.1.4.2
DE   Glycerophosphocholine phosphodiesterase.
CA   sn-glycero-3-phosphocholine + H(2)O = choline + sn-glycerol 3-phosphate.
CC   -!- Also acts on sn-glycero-3-phosphoethanolamine.
//
ID   3.1.4.3
DE   Phospholipase C.
AN   Clostridium oedematiens beta- and gamma-toxins.
AN   Clostridium welchii alpha-toxin.
AN   Lecithinase C.
AN   Lipophosphodiesterase I.
CA   A phosphatidylcholine + H(2)O = 1,2-diacylglycerol + choline phosphate.
CF   Zinc.
CC   -!- The bacterial enzyme also acts on sphingomyelin and
CC       phosphatidylinositol.
CC   -!- The enzyme from seminal plasma does not act on phosphatidylinositol.
PR   PROSITE; PDOC00357;
DR   Q04001, PHLA_MYCTU ;  P95246, PHLB_MYCTU ;  P0C216, PHLC1_CLOPE;
DR   Q9RF12, PHLC2_CLOPE;  P09598, PHLC_BACCE ;  P20419, PHLC_CLOBI ;
DR   P59026, PHLC_CLOHA ;  Q46150, PHLC_CLONO ;  Q0TV31, PHLC_CLOP1 ;
DR   Q8VUZ6, PHLC_CLOSO ;  P33378, PHLC_LISMO ;  P95245, PHLC_MYCTU ;
DR   P06200, PHLC_PSEAE ;  Q2FWP1, PHLC_STAA8 ;  Q5HEI1, PHLC_STAAC ;
DR   P09978, PHLC_STAAU ;  P33376, PHLD_BACCE ;  P0A5R9, PHLD_MYCBO ;
DR   P0A5R8, PHLD_MYCTU ;  Q9RGS8, PHLN_BURPS ;  P15713, PHLN_PSEAE ;
//
ID   3.1.4.4
DE   Phospholipase D.
AN   Choline phosphatase.
AN   Lecithinase D.
AN   Lipophosphodiesterase II.
CA   A phosphatidylcholine + H(2)O = choline + a phosphatidate.
CC   -!- Also acts on other phosphatidyl esters.
DR   P0CE78, A1H1_LOXRE ;  P0CE79, A1H2_LOXRE ;  O08684, PLD1_CRIGR ;
DR   Q13393, PLD1_HUMAN ;  Q9Z280, PLD1_MOUSE ;  P70496, PLD1_RAT   ;
DR   Q0V8L6, PLD2_BOVIN ;  O14939, PLD2_HUMAN ;  P97813, PLD2_MOUSE ;
DR   P70498, PLD2_RAT   ;  Q2KJJ8, PLD3_BOVIN ;  Q8IV08, PLD3_HUMAN ;
DR   Q4R583, PLD3_MACFA ;  O35405, PLD3_MOUSE ;  Q5R4Y7, PLD3_PONAB ;
DR   Q5FVH2, PLD3_RAT   ;  Q6PB03, PLD3_XENLA ;  Q640B3, PLD3_XENTR ;
DR   Q96BZ4, PLD4_HUMAN ;  Q8BG07, PLD4_MOUSE ;  Q38882, PLDA1_ARATH;
DR   O82549, PLDA1_BRAOC;  Q70EW5, PLDA1_CYNCA;  Q43270, PLDA1_MAIZE;
DR   Q43007, PLDA1_ORYSJ;  O04883, PLDA1_PIMBR;  Q41142, PLDA1_RICCO;
DR   P93400, PLDA1_TOBAC;  O04865, PLDA1_VIGUN;  Q9SSQ9, PLDA2_ARATH;
DR   P55939, PLDA2_BRAOC;  P93844, PLDA2_ORYSJ;  Q54UK0, PLDA_DICDI ;
DR   P93733, PLDB1_ARATH;  O23078, PLDB2_ARATH;  Q54WR4, PLDB_DICDI ;
DR   Q54Z25, PLDC_DICDI ;  Q9C5Y0, PLDD1_ARATH;  Q9C888, PLDE1_ARATH;
DR   Q9T053, PLDG1_ARATH;  Q9T051, PLDG2_ARATH;  Q9T052, PLDG3_ARATH;
DR   O17405, PLDL_CAEEL ;  Q9LRZ5, PLDP1_ARATH;  Q9M9W8, PLDP2_ARATH;
DR   Q54K50, PLDY_DICDI ;  P58766, PLDZ1_ARATH;  Q54SA1, PLDZ_DICDI ;
DR   Q59121, PLD_ARCHD  ;  P20626, PLD_CORPS  ;  Q59332, PLD_CORUL  ;
DR   Q5BMR2, PLD_PHYIN  ;  Q1RK58, PLD_RICBR  ;  Q92G53, PLD_RICCN  ;
DR   Q4UJZ1, PLD_RICFE  ;  Q9ZCD8, PLD_RICPR  ;  Q68VT0, PLD_RICTY  ;
DR   Q53728, PLD_STRAT  ;  Q8KRU5, PLD_STRCW  ;  P36126, SPO14_YEAST;
//
ID   3.1.4.5
DE   Transferred entry: 3.1.21.1.
//
ID   3.1.4.6
DE   Transferred entry: 3.1.22.1.
//
ID   3.1.4.7
DE   Transferred entry: 3.1.31.1.
//
ID   3.1.4.8
DE   Transferred entry: 3.1.27.3.
//
ID   3.1.4.9
DE   Transferred entry: 3.1.30.2.
//
ID   3.1.4.10
DE   Transferred entry: 4.6.1.13.
//
ID   3.1.4.11
DE   Phosphoinositide phospholipase C.
AN   1-phosphatidyl-D-myo-inositol-4,5-bisphosphate
AN   inositoltrisphosphohydrolase.
AN   1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase.
AN   Monophosphatidylinositol phosphodiesterase.
AN   Phosphatidylinositol phospholipase C.
AN   Phosphoinositidase C.
AN   PI-PLC.
AN   Triphosphoinositide phosphodiesterase.
CA   1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol
CA   1,4,5-trisphosphate + diacylglycerol.
CC   -!- These enzymes form some of the cyclic phosphate Ins(cyclic
CC       1,2)P(4,5)P(2) as well as Ins(1,4,5)P(3).
CC   -!- They show activity toward phosphatidylinositol, i.e., the activity of
CC       EC 4.6.1.13 in vitro at high calcium concentration.
DR   P25455, PIP1_DROME ;  P13217, PIPA_DROME ;  O13433, PLC1_CANAL ;
DR   P40977, PLC1_SCHPO ;  P32383, PLC1_YEAST ;  P10894, PLCB1_BOVIN;
DR   Q9NQ66, PLCB1_HUMAN;  Q9Z1B3, PLCB1_MOUSE;  P10687, PLCB1_RAT  ;
DR   Q00722, PLCB2_HUMAN;  A3KGF7, PLCB2_MOUSE;  O89040, PLCB2_RAT  ;
DR   Q01970, PLCB3_HUMAN;  P51432, PLCB3_MOUSE;  Q99JE6, PLCB3_RAT  ;
DR   Q07722, PLCB4_BOVIN;  Q15147, PLCB4_HUMAN;  Q9QW07, PLCB4_RAT  ;
DR   Q39032, PLCD1_ARATH;  P10895, PLCD1_BOVIN;  P51178, PLCD1_HUMAN;
DR   Q8R3B1, PLCD1_MOUSE;  P10688, PLCD1_RAT  ;  Q39033, PLCD2_ARATH;
DR   Q56W08, PLCD3_ARATH;  Q8N3E9, PLCD3_HUMAN;  Q8K2J0, PLCD3_MOUSE;
DR   Q944C1, PLCD4_ARATH;  P21671, PLCD4_BOVIN;  Q9BRC7, PLCD4_HUMAN;
DR   Q4R6L3, PLCD4_MACFA;  Q8K3R3, PLCD4_MOUSE;  Q8SPR7, PLCD4_PIG  ;
DR   Q5RET0, PLCD4_PONAB;  Q62711, PLCD4_RAT  ;  Q32NH8, PLCD4_XENLA;
DR   Q944C2, PLCD5_ARATH;  Q8GV43, PLCD6_ARATH;  Q9LY51, PLCD7_ARATH;
DR   Q9STZ3, PLCD8_ARATH;  Q6NMA7, PLCD9_ARATH;  Q9P212, PLCE1_HUMAN;
DR   Q8K4S1, PLCE1_MOUSE;  Q99P84, PLCE1_RAT  ;  P08487, PLCG1_BOVIN;
DR   P19174, PLCG1_HUMAN;  Q62077, PLCG1_MOUSE;  P10686, PLCG1_RAT  ;
DR   P16885, PLCG2_HUMAN;  Q8CIH5, PLCG2_MOUSE;  P24135, PLCG2_RAT  ;
DR   Q4KWH8, PLCH1_HUMAN;  Q4KWH5, PLCH1_MOUSE;  O75038, PLCH2_HUMAN;
DR   A2AP18, PLCH2_MOUSE;  Q1RML2, PLCZ1_BOVIN;  Q2VRL0, PLCZ1_CHICK;
DR   Q86YW0, PLCZ1_HUMAN;  Q95JS1, PLCZ1_MACFA;  Q8K4D7, PLCZ1_MOUSE;
DR   Q7YRU3, PLCZ1_PIG  ;  Q5FX52, PLCZ1_RAT  ;  Q02158, PLC_DICDI  ;
DR   A5D6R3, PLD3A_DANRE;
//
ID   3.1.4.12
DE   Sphingomyelin phosphodiesterase.
AN   Acid sphingomyelinase.
AN   Neutral sphingomyelinase.
CA   Sphingomyelin + H(2)O = N-acylsphingosine + choline phosphate.
CC   -!- Has very little activity on phosphatidylcholine.
DR   Q10916, ASM1_CAEEL ;  Q23498, ASM2_CAEEL ;  Q9UAY4, ASM3_CAEEL ;
DR   Q0VD19, ASM_BOVIN  ;  P17405, ASM_HUMAN  ;  Q04519, ASM_MOUSE  ;
DR   Q6UWV6, ENPP7_HUMAN;  Q5EZ72, ENPP7_RAT  ;  Q9NY59, NSMA2_HUMAN;
DR   Q9JJY3, NSMA2_MOUSE;  O35049, NSMA2_RAT  ;  Q6PFJ7, NSMA3_DANRE;
DR   Q9NXE4, NSMA3_HUMAN;  Q6ZPR5, NSMA3_MOUSE;  Q5XHG1, NSMA3_XENLA;
DR   O45870, NSMA_CAEEL ;  Q9VZS6, NSMA_DROME ;  O60906, NSMA_HUMAN ;
DR   O70572, NSMA_MOUSE ;  Q9ET64, NSMA_RAT   ;  O74369, NSMA_SCHPO ;
DR   P09599, PHL1_BACCE ;  Q72P44, PHL1_LEPIC ;  P59115, PHL1_LEPIN ;
DR   P11889, PHL2_BACCE ;  P59116, PHL2_LEPIN ;  P33377, PHL3_BACCE ;
DR   Q9RLV9, PHLC_LISIV ;  P80924, PHLC_STAIN ;  P17627, PHL_LEPIN  ;
DR   Q1ZXD9, Y8017_DICDI;
//
ID   3.1.4.13
DE   Serine-ethanolaminephosphate phosphodiesterase.
CA   Serine phosphoethanolamine + H(2)O = serine + ethanolamine phosphate.
CC   -!- Acts only on those phosphodiesters that have ethanolamine as a
CC       component part of the molecule.
//
ID   3.1.4.14
DE   [Acyl-carrier-protein] phosphodiesterase.
AN   [Acyl-carrier-protein] 4'-pantetheine-phosphohydrolase.
AN   ACP hydrolyase.
AN   ACP phosphodiesterase.
CA   Holo-[acyl-carrier-protein] + H(2)O = 4'-phosphopantetheine + apo-[acyl-
CA   carrier-protein].
CC   -!- The enzyme cleaves acyl-[acyl-carrier-protein] species with acyl
CC       chains of 6-16 carbon atoms although it appears to demonstrate a
CC       preference for the unacylated acyl-carrier-protein (ACP) and short-
CC       chain ACPs over the medium- and long-chain species.
CC   -!- Deletion of the gene encoding this enzyme abolishes ACP prosthetic-
CC       group turnover in vivo.
CC   -!- Activation of apo-ACP to form the holoenzyme is carried out by
CC       EC 2.7.8.7.
DR   A7ZIF6, ACPH_ECO24 ;  B7UJM7, ACPH_ECO27 ;  B7MD62, ACPH_ECO45 ;
DR   B7L637, ACPH_ECO55 ;  Q8XE96, ACPH_ECO57 ;  B5Z2W0, ACPH_ECO5E ;
DR   B7NJ98, ACPH_ECO7I ;  B7MPG5, ACPH_ECO81 ;  B7M3P3, ACPH_ECO8A ;
DR   C4ZTG1, ACPH_ECOBW ;  B1XEZ2, ACPH_ECODH ;  A7ZX55, ACPH_ECOHS ;
DR   Q0TKN7, ACPH_ECOL5 ;  Q8FKC6, ACPH_ECOL6 ;  B1J045, ACPH_ECOLC ;
DR   P21515, ACPH_ECOLI ;  B7N8V6, ACPH_ECOLU ;  B6HZK4, ACPH_ECOSE ;
DR   B1LJF2, ACPH_ECOSM ;  A4W777, ACPH_ENT38 ;  Q6D857, ACPH_ERWCT ;
DR   B7LMI3, ACPH_ESCF3 ;  B5Y0Y9, ACPH_KLEP3 ;  A6T5D6, ACPH_KLEP7 ;
DR   Q7N0I2, ACPH_PHOLL ;  B5EWT7, ACPH_SALA4 ;  A9MM59, ACPH_SALAR ;
DR   Q57SG0, ACPH_SALCH ;  B5FKQ8, ACPH_SALDC ;  B5QTF2, ACPH_SALEP ;
DR   B5R6Q5, ACPH_SALG2 ;  B4T8P3, ACPH_SALHS ;  B4SWP4, ACPH_SALNS ;
DR   Q5PFT4, ACPH_SALPA ;  A9MX32, ACPH_SALPB ;  C0Q7S7, ACPH_SALPC ;
DR   B5BDD0, ACPH_SALPK ;  B4TZH7, ACPH_SALSV ;  Q8XEZ8, ACPH_SALTI ;
DR   Q7CR41, ACPH_SALTY ;  A8GAM3, ACPH_SERP5 ;  B2U407, ACPH_SHIB3 ;
DR   Q325J7, ACPH_SHIBS ;  Q32JF8, ACPH_SHIDS ;  Q83SG7, ACPH_SHIFL ;
DR   Q3Z505, ACPH_SHISS ;  A1JNT5, ACPH_YERE8 ;  A7FLF7, ACPH_YERP3 ;
DR   Q8ZC31, ACPH_YERPE ;  Q66DW7, ACPH_YERPS ;
//
ID   3.1.4.15
DE   Adenylyl-[glutamate--ammonia ligase] hydrolase.
CA   Adenylyl-[L-glutamate:ammonia ligase (ADP-forming)] + H(2)O = adenylate +
CA   [L-glutamate:ammonia ligase (ADP-forming)].
//
ID   3.1.4.16
DE   2',3'-cyclic-nucleotide 2'-phosphodiesterase.
CA   Nucleoside 2',3'-cyclic phosphate + H(2)O = nucleoside 3'-phosphate.
CC   -!- Also hydrolyzes 3'-nucleoside monophosphates and bis-4-nitrophenyl
CC       phosphate, but not 3'-deoxynucleotides.
CC   -!- Similar reactions are carried out by EC 3.1.27.3 and EC 3.1.27.5.
PR   PROSITE; PDOC00627;
DR   P08331, CPDB_ECOLI ;  P44764, CPDB_HAEIN ;  P26265, CPDB_SALTY ;
DR   P53052, CPDB_YEREN ;  O34313, NTPES_BACSU;
//
ID   3.1.4.17
DE   3',5'-cyclic-nucleotide phosphodiesterase.
AN   Cyclic AMP phosphodiesterase.
CA   Nucleoside 3',5'-cyclic phosphate + H(2)O = nucleoside 5'-phosphate.
CC   -!- Acts on 3',5'-cyclic AMP, 3',5'-cyclic dAMP, 3',5'-cyclic IMP,
CC       3',5'-cyclic GMP and 3',5'-cyclic CMP.
PR   PROSITE; PDOC00116;
PR   PROSITE; PDOC00530;
DR   Q56686, CPDP_VIBFI ;  Q8ZD92, CPDP_YERPE ;  Q9Y233, PDE10_HUMAN;
DR   Q8CA95, PDE10_MOUSE;  Q9QYJ6, PDE10_RAT  ;  Q9VJ79, PDE11_DROME;
DR   Q9HCR9, PDE11_HUMAN;  P0C1Q2, PDE11_MOUSE;  Q8VID6, PDE11_RAT  ;
DR   Q1KKS3, PDE11_TAKRU;  P14100, PDE1A_BOVIN;  P54750, PDE1A_HUMAN;
DR   Q61481, PDE1A_MOUSE;  Q01061, PDE1B_BOVIN;  Q64395, PDE1B_CRIGR;
DR   Q01064, PDE1B_HUMAN;  Q01065, PDE1B_MOUSE;  Q01066, PDE1B_RAT  ;
DR   Q14123, PDE1C_HUMAN;  Q64338, PDE1C_MOUSE;  Q63421, PDE1C_RAT  ;
DR   O18696, PDE1_CAEEL ;  P32782, PDE1_CANAL ;  P36599, PDE1_SCHPO ;
DR   P22434, PDE1_YEAST ;  P14099, PDE2A_BOVIN;  O00408, PDE2A_HUMAN;
DR   Q922S4, PDE2A_MOUSE;  Q01062, PDE2A_RAT  ;  P30645, PDE2_CAEEL ;
DR   P06776, PDE2_YEAST ;  Q14432, PDE3A_HUMAN;  Q9Z0X4, PDE3A_MOUSE;
DR   Q62865, PDE3A_RAT  ;  Q13370, PDE3B_HUMAN;  Q61409, PDE3B_MOUSE;
DR   Q63085, PDE3B_RAT  ;  Q8I0P7, PDE3_CAEEL ;  O89085, PDE4A_CAVPO;
DR   Q9W4T4, PDE4A_DROME;  P27815, PDE4A_HUMAN;  O89084, PDE4A_MOUSE;
DR   P54748, PDE4A_RAT  ;  P12252, PDE4B_DROME;  Q07343, PDE4B_HUMAN;
DR   P14646, PDE4B_RAT  ;  Q9W4S9, PDE4C_DROME;  Q08493, PDE4C_HUMAN;
DR   Q3UEI1, PDE4C_MOUSE;  P14644, PDE4C_RAT  ;  Q9W4T0, PDE4D_DROME;
DR   Q08499, PDE4D_HUMAN;  Q01063, PDE4D_MOUSE;  P14270, PDE4D_RAT  ;
DR   Q8IRU4, PDE4E_DROME;  Q22000, PDE4_CAEEL ;  P91119, PDE5_CAEEL ;
DR   Q9N2V9, PDE6_CAEEL ;  Q13946, PDE7A_HUMAN;  P70453, PDE7A_MOUSE;
DR   O08593, PDE7A_RAT  ;  Q9NP56, PDE7B_HUMAN;  Q9QXQ1, PDE7B_MOUSE;
DR   O60658, PDE8A_HUMAN;  O88502, PDE8A_MOUSE;  O95263, PDE8B_HUMAN;
//
ID   3.1.4.18
DE   Transferred entry: 3.1.16.1.
//
ID   3.1.4.19
DE   Transferred entry: 3.1.13.3.
//
ID   3.1.4.20
DE   Transferred entry: 3.1.13.1.
//
ID   3.1.4.21
DE   Transferred entry: 3.1.30.1.
//
ID   3.1.4.22
DE   Transferred entry: 3.1.27.5.
//
ID   3.1.4.23
DE   Transferred entry: 3.1.27.1.
//
ID   3.1.4.24
DE   Deleted entry.
//
ID   3.1.4.25
DE   Transferred entry: 3.1.11.1.
//
ID   3.1.4.26
DE   Deleted entry.
//
ID   3.1.4.27
DE   Transferred entry: 3.1.11.2.
//
ID   3.1.4.28
DE   Transferred entry: 3.1.11.3.
//
ID   3.1.4.29
DE   Deleted entry.
//
ID   3.1.4.30
DE   Transferred entry: 3.1.21.2.
//
ID   3.1.4.31
DE   Transferred entry: 3.1.11.4.
//
ID   3.1.4.32
DE   Deleted entry.
//
ID   3.1.4.33
DE   Deleted entry.
//
ID   3.1.4.34
DE   Deleted entry.
//
ID   3.1.4.35
DE   3',5'-cyclic-GMP phosphodiesterase.
CA   Guanosine 3',5'-cyclic phosphate + H(2)O = guanosine 5'-phosphate.
PR   PROSITE; PDOC00116;
DR   P22571, CNCG_BOVIN ;  Q13956, CNCG_HUMAN ;  P61249, CNCG_MOUSE ;
DR   P61250, CNCG_RAT   ;  O55175, CNCG_SPETR ;  P04972, CNRG_BOVIN ;
DR   P54827, CNRG_CANFA ;  Q9EQQ8, CNRG_CAVPO ;  P61248, CNRG_FELCA ;
DR   P18545, CNRG_HUMAN ;  P09174, CNRG_MOUSE ;  Q9Y233, PDE10_HUMAN;
DR   Q8CA95, PDE10_MOUSE;  Q9QYJ6, PDE10_RAT  ;  Q9VJ79, PDE11_DROME;
DR   Q9HCR9, PDE11_HUMAN;  P0C1Q2, PDE11_MOUSE;  Q8VID6, PDE11_RAT  ;
DR   Q1KKS3, PDE11_TAKRU;  P12019, PDE1_DICDI ;  B0G0Y8, PDE3_DICDI ;
DR   Q28156, PDE5A_BOVIN;  O77746, PDE5A_CANFA;  O76074, PDE5A_HUMAN;
DR   Q8CG03, PDE5A_MOUSE;  O54735, PDE5A_RAT  ;  Q8MLZ3, PDE5_DICDI ;
DR   P11541, PDE6A_BOVIN;  Q28263, PDE6A_CANFA;  P16499, PDE6A_HUMAN;
DR   P27664, PDE6A_MOUSE;  P23439, PDE6B_BOVIN;  P33726, PDE6B_CANFA;
DR   P35913, PDE6B_HUMAN;  P23440, PDE6B_MOUSE;  P16586, PDE6C_BOVIN;
DR   P52731, PDE6C_CHICK;  P51160, PDE6C_HUMAN;  Q91ZQ1, PDE6C_MOUSE;
DR   Q8MM62, PDE6_DICDI ;  B3LVW5, PDE6_DROAN ;  B3P3K2, PDE6_DROER ;
DR   B4JXX2, PDE6_DROGR ;  Q9VFI9, PDE6_DROME ;  B4K9L4, PDE6_DROMO ;
DR   B4G4E5, PDE6_DROPE ;  Q298P4, PDE6_DROPS ;  B4HEM4, PDE6_DROSE ;
DR   B4QZU1, PDE6_DROSI ;  B4LVU6, PDE6_DROVI ;  B4NAL6, PDE6_DROWI ;
DR   B4PSS5, PDE6_DROYA ;  Q54HY0, PDE7_DICDI ;  O76083, PDE9A_HUMAN;
DR   O70628, PDE9A_MOUSE;
//
ID   3.1.4.36
DE   Transferred entry: 3.1.4.43.
//
ID   3.1.4.37
DE   2',3'-cyclic-nucleotide 3'-phosphodiesterase.
AN   Cyclic-CMP phosphodiesterase.
CA   Nucleoside 2',3'-cyclic phosphate + H(2)O = nucleoside 2'-phosphate.
CC   -!- The brain enzyme acts on 2',3'-cyclic AMP more rapidly than on the
CC       UMP or CMP derivatives.
CC   -!- An enzyme from liver acts on 2',3'-cyclic CMP more rapidly than on
CC       the purine derivatives; it also hydrolyzes the corresponding
CC       3',5'-cyclic phosphates, more slowly.
CC   -!- This latter enzyme has been called cyclic-CMP phosphodiesterase.
DR   P06623, CN37_BOVIN ;  P09543, CN37_HUMAN ;  P16330, CN37_MOUSE ;
DR   Q5RFD0, CN37_PONAB ;  P13233, CN37_RAT   ;  Q758H6, CPD1_ASHGO ;
DR   Q59PZ7, CPD1_CANAL ;  Q6FTX0, CPD1_CANGA ;  Q6BGW3, CPD1_DEBHA ;
DR   Q6CXV0, CPD1_KLULA ;  Q7S724, CPD1_NEUCR ;  Q0UME8, CPD1_PHANO ;
DR   Q6CGD3, CPD1_YARLI ;  P53314, CPD1_YEAST ;
//
ID   3.1.4.38
DE   Glycerophosphocholine cholinephosphodiesterase.
CA   sn-glycero-3-phosphocholine + H(2)O = glycerol + choline phosphate.
CC   -!- No activity on sn-3-glycerophosphoethanolamine.
//
ID   3.1.4.39
DE   Alkylglycerophosphoethanolamine phosphodiesterase.
AN   Lysophospholipase D.
CA   1-alkyl-sn-glycero-3-phosphoethanolamine + H(2)O = 1-alkyl-sn-glycerol
CA   3-phosphate + ethanolamine.
CC   -!- Also acts on acyl and choline analogs.
DR   A1A4K5, ENPP2_BOVIN;  Q13822, ENPP2_HUMAN;  Q9R1E6, ENPP2_MOUSE;
DR   Q64610, ENPP2_RAT  ;
//
ID   3.1.4.40
DE   CMP-N-acylneuraminate phosphodiesterase.
AN   CMP-sialate hydrolase.
CA   CMP-N-acylneuraminate + H(2)O = CMP + N-acylneuraminate.
//
ID   3.1.4.41
DE   Sphingomyelin phosphodiesterase D.
CA   Sphingomyelin + H(2)O = ceramide phosphate + choline.
CC   -!- Does not act on phosphatidylcholine, but hydrolyzes
CC       2-lysophosphatidylcholine to choline and 2-lysophosphatidate.
DR   C0JAT4, A1H1_LOXHI ;  P0CE78, A1H1_LOXRE ;  C0JAT9, A1H1_LOXSP ;
DR   C0JAT5, A1H2_LOXHI ;  P0CE79, A1H2_LOXRE ;  C0JAU1, A1H2_LOXSP ;
DR   C0JAT6, A1H3_LOXHI ;  C0JAU2, A1H3_LOXSP ;  C0JAT8, A1H4_LOXHI ;
DR   P0CE80, A1HA_LOXIN ;  P0CE81, A1HB1_LOXIN;  P0CE82, A1HB2_LOXIN;
DR   Q4VDB5, A1H_LOXGA  ;  Q56JA9, A1H_LOXSM  ;  C0JAS6, A1I1_LOXSP ;
DR   C0JAS7, A1I2_LOXSP ;  C0JAS8, A1I3_LOXSP ;  C0JAT3, A1I4_LOXSP ;
DR   C0JAQ5, A1IA1_LOXHI;  P0CE83, A1IA1_LOXIN;  C0JAQ8, A1IA2_LOXHI;
DR   P0CE84, A1IA2_LOXIN;  C0JAQ9, A1IA3_LOXHI;  B2KKV8, A1IA3_LOXIN;
DR   C0JAR0, A1IA4_LOXHI;  C0JAR2, A1IA5_LOXHI;  C0JAR3, A1IA6_LOXHI;
DR   C0JAR7, A1IA7_LOXHI;  C0JAR8, A1IA8_LOXHI;  C0JAR9, A1IB1_LOXHI;
DR   B2KKV6, A1IB1_LOXIN;  C0JAS0, A1IB2_LOXHI;  B2KKV7, A1IB2_LOXIN;
DR   C0JAS1, A1IB3_LOXHI;  C0JAS2, A1IB4_LOXHI;  C0JAS3, A1IB5_LOXHI;
DR   C0JAS4, A1IB6_LOXHI;  C0JAV3, A1KA1_LOXAP;  Q4ZFU1, A1KA1_LOXAR;
DR   C0JAW6, A1KA1_LOXDE;  C0JAY1, A1KA1_LOXSA;  C0JAV4, A1KA2_LOXAP;
DR   C0JAV0, A1KA2_LOXAR;  C0JAW7, A1KA2_LOXDE;  C0JAY4, A1KA2_LOXSA;
DR   C0JAV5, A1KA3_LOXAP;  C0JAV1, A1KA3_LOXAR;  C0JAW8, A1KA3_LOXDE;
DR   C0JAY5, A1KA3_LOXSA;  C0JAV6, A1KA4_LOXAP;  C0JAV2, A1KA4_LOXAR;
DR   C0JAW9, A1KA4_LOXDE;  C0JAY8, A1KA4_LOXSA;  C0JAX0, A1KA5_LOXDE;
DR   C0JAY9, A1KA5_LOXSA;  C0JAX1, A1KA6_LOXDE;  C0JAZ0, A1KA6_LOXSA;
DR   Q5YD77, A1KA_LOXBO ;  C0JAV8, A1KB1_LOXAP;  C0JAW4, A1KB1_LOXDE;
DR   C0JAY2, A1KB1_LOXSA;  C0JAV9, A1KB2_LOXAP;  C0JAW5, A1KB2_LOXDE;
DR   C0JAY3, A1KB2_LOXSA;  C0JAW2, A1KB3_LOXAP;  C0JAW0, A1KB_LOXAR ;
DR   P0C2K0, A1KB_LOXBO ;  C0JAV7, A1KC_LOXAP ;  C0JAW3, A1KC_LOXAR ;
DR   Q5YD75, A1K_LOXRE  ;  C0JAU7, A1L1_LOXSA ;  C0JAU8, A1L2_LOXSA ;
DR   C0JAU9, A1L3_LOXSA ;  Q7Z1Y7, A1LA_LOXAR ;  Q4ZFU2, A1LB1_LOXAR;
DR   C0JAU4, A1LB2_LOXAR;  C0JAU6, A1LC_LOXAR ;  C0JAU3, A1L_LOXAP  ;
DR   C0JAU5, A1L_LOXDE  ;  C0JAX3, A1MA1_LOXDE;  C0JAX4, A1MA2_LOXDE;
DR   C0JAX5, A1MA3_LOXDE;  C0JAX7, A1MA4_LOXDE;  C0JAX9, A1MA5_LOXDE;
DR   C0JAY0, A1MA6_LOXDE;  C0JAX2, A1MB_LOXDE ;  C0JAZ1, A1OA1_LOXVA;
DR   C0JAZ2, A1OA2_LOXVA;  C0JAZ3, A1OA3_LOXVA;  C0JB03, A1OA_LOXRU ;
DR   C0JAZ4, A1OB1_LOXVA;  C0JAZ5, A1OB2_LOXVA;  C0JAZ6, A1OB3_LOXVA;
DR   C0JAZ7, A1OB4_LOXVA;  C0JAZ8, A1OB5_LOXVA;  C0JB00, A1OB_LOXRU ;
DR   C0JB01, A1OC_LOXRU ;  C0JB02, A1OD_LOXRU ;  C0JAZ9, A1O_LOXAM  ;
DR   C0JB04, A1P_LOXRU  ;  Q7Z1N0, A1X1_LOXAR ;  P0C2K2, A1X1_LOXGA ;
DR   P0C2L0, A1X1_LOXIN ;  Q7M485, A1X1_LOXRE ;  P69502, A1XA_LOXGA ;
DR   C0JB07, A21_LOXAP  ;  C0JB08, A21_LOXAR  ;  Q1W695, A21_LOXIN  ;
DR   C0JB05, A21_LOXSP  ;  C0JB06, A21_LOXVA  ;  B2KKW0, A22_LOXIN  ;
DR   Q8I914, A311_LOXLA ;  C0JB10, A311_LOXS4 ;  Q1KY80, A312_LOXLA ;
DR   C0JB11, A312_LOXS4 ;  C0JB09, A31_LOXAR  ;  Q1KY79, A32_LOXLA  ;
DR   Q8I913, A331_LOXLA ;  C0JB12, A332_LOXLA ;  C0JB13, A333_LOXLA ;
DR   P0C2L1, A3X1_LOXLA ;  C0JB18, A411_LOXAM ;  C0JB14, A411_LOXHI ;
DR   C0JB23, A411_LOXLA ;  C0JB19, A412_LOXAM ;  C0JB15, A412_LOXHI ;
DR   C0JB24, A412_LOXLA ;  C0JB20, A413_LOXAM ;  C0JB16, A413_LOXHI ;
DR   C0JB22, A41_LOXAR  ;  C0JB21, A41_LOXRU  ;  C0JB25, A421_LOXLA ;
DR   C0JB26, A422_LOXLA ;  C0JB27, A423_LOXLA ;  C0JB28, A424_LOXLA ;
DR   C0JB17, A42_LOXHI  ;  C0JB29, A43_LOXLA  ;  A4USB4, A51_LOXIN  ;
DR   C0JB31, A611_LOXHI ;  C0JB32, A612_LOXHI ;  C0JB30, A71_LOXAR  ;
DR   P0C2K1, AX1_LOXDE  ;  Q2XQ09, B1H1_LOXIN ;  Q27Q54, B1H2_LOXIN ;
DR   Q8I912, B1H_LOXLA  ;  C0JB35, B1KA_SICPE ;  C0JB36, B1KB_SICPE ;
DR   C0JB37, B1LA_SICPE ;  C0JB38, B1LB_SICPE ;  C0JB33, B1M_SICPE  ;
DR   C0JB34, B1N_SICPE  ;  C0JB39, B1O_SICTE  ;  Q1W694, B1Q_LOXIN  ;
DR   C0JB49, B1R1_LOXSN ;  C0JB50, B1R2_LOXSN ;  C0JB51, B1R_LOXAS  ;
DR   C0JB41, B1S1_LOXSN ;  C0JB42, B1S2_LOXSN ;  C0JB43, B1S3_LOXSN ;
DR   C0JB48, B1S_LOXAS  ;  C0JB44, B1T1_LOXSN ;  C0JB45, B1T2_LOXSN ;
DR   C0JB46, B1U1_LOXSN ;  C0JB47, B1U2_LOXSN ;  C0JB55, B1V_SICCD  ;
DR   C0JB52, B1V_SICPA  ;  C0JB53, B1V_SICPE  ;  C0JB54, B1V_SICTE  ;
DR   C0JB68, B2H_SICPA  ;  C0JB67, B2H_SICPE  ;  C0JB60, B2I1_SICPE ;
DR   C0JB58, B2I2_SICPE ;  C0JB61, B2I3_SICPE ;  C0JB62, B2I4_SICPE ;
DR   C0JB65, B2I5_SICPE ;  C0JB69, B2I_SICPA  ;  C0JB56, B2J1_SICPE ;
DR   C0JB57, B2J2_SICPE ;  C0JB70, B2J_SICPA  ;  C0JB76, B2KA1_SICCD;
DR   C0JB77, B2KA2_SICCD;  C0JB78, B2KA3_SICCD;  C0JB79, B2KA4_SICCD;
DR   C0JB71, B2KB1_SICCD;  C0JB72, B2KB2_SICCD;  C0JB73, B2KB3_SICCD;
DR   C0JB74, B2KB4_SICCD;  C0JB75, B2KB5_SICCD;  C0JB80, B2KB6_SICCD;
DR   C0JB81, B2KB7_SICCD;  C0JB82, B2KB8_SICCD;  C0JB83, B2KB9_SICCD;
DR   C0JB84, B2KBA_SICCD;  C0JB85, B2KBB_SICCD;  C0JB86, B2KBC_SICCD;
DR   C0JB87, B2KBD_SICCD;  C0JB88, B2KBE_SICCD;  C0JB91, B2K_SICAL  ;
DR   C0JB89, B2L1_SICCD ;  C0JB90, B2L2_SICCD ;  C0JB94, B312_LOXSN ;
DR   C0JB92, B31_LOXSN  ;  C0JB93, B32_LOXSN  ;  P0C2K3, BX17_LOXGA ;
DR   P0C2K4, BX2_LOXGA  ;  P0C2K5, BX3_LOXGA  ;  P0C2K6, BX4_LOXGA  ;
DR   P0C2K9, BX8_LOXGA  ;  Q202J4, SMD_IXOSC  ;  P0C2K7, X5_LOXGA   ;
DR   P0C2K8, X6_LOXGA   ;
//
ID   3.1.4.42
DE   Glycerol-1,2-cyclic-phosphate 2-phosphodiesterase.
CA   Glycerol 1,2-cyclic phosphate + H(2)O = glycerol 1-phosphate.
CC   -!- Acts on both stereoisomers of the substrate and also, more slowly,
CC       on 3',5'-cyclic AMP and on 2',3'-cyclic AMP.
//
ID   3.1.4.43
DE   Glycerophosphoinositol inositolphosphodiesterase.
AN   1,2-cyclic-inositol-phosphate phosphodiesterase.
AN   1-D-myo-inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase.
AN   D-inositol 1,2-cyclic phosphate 2-phosphohydrolase.
AN   D-myo-inositol 1,2-cyclic phosphate 2-phosphohydrolase.
AN   D-myo-inositol 1:2-cyclic phosphate 2-phosphohydrolase.
AN   Inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase.
CA   1-(sn-glycero-3-phospho)-1D-myo-inositol + H(2)O = glycerol + 1D-myo-
CA   inositol 1-phosphate.
CC   -!- This enzyme also hydrolyzes Ins(cyclic 1,2)P to Ins-1-P.
CC   -!- Formerly EC 3.1.4.36.
DR   Q9HCC8, GDPD2_HUMAN;  Q9ESM6, GDPD2_MOUSE;
//
ID   3.1.4.44
DE   Glycerophosphoinositol glycerophosphodiesterase.
AN   sn-glycero(3)phosphoinositol glycerophosphohydrolase.
AN   sn-glycero-3-phospho-1-inositol glycerophosphohydrolase.
CA   1-(sn-glycero-3-phospho)-1D-myo-inositol + H(2)O = myo-inositol +
CA   sn-glycerol 3-phosphate.
DR   Q3T0T0, GDE1_BOVIN ;  Q9NZC3, GDE1_HUMAN ;  Q9JL56, GDE1_MOUSE ;
DR   Q9JL55, GDE1_RAT   ;
//
ID   3.1.4.45
DE   N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase.
AN   Alpha-N-acetylglucosaminyl phosphodiesterase.
AN   Lysosomal alpha-N-acetylglucosaminidase.
CA   Glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H(2)O =
CA   N-acetyl-D-glucosamine + glycoprotein phospho-D-mannose.
CC   -!- Acts on a variety of compounds in which N-acetyl-D-glucosamine is
CC       alpha-linked to a phosphate group, including the biosynthetic in
CC       intermediates of the high mannose oligosaccharide components of some
CC       lysosomal enzymes and the product of EC 2.7.8.17.
DR   P68827, NAGPA_BOVIN;  Q9UK23, NAGPA_HUMAN;  Q8BJ48, NAGPA_MOUSE;
//
ID   3.1.4.46
DE   Glycerophosphodiester phosphodiesterase.
AN   Glycerophosphoryl diester phosphodiesterase.
CA   A glycerophosphodiester + H(2)O = an alcohol + sn-glycerol 3-phosphate.
CC   -!- Broad specificity for glycerophosphodiesters; glycerophosphocholine,
CC       glycerophosphoethanolamine, glycerophosphoglycerol and
CC       bis(glycerophospho)-glycerol are hydrolyzed.
DR   Q74ZH9, GDE1_ASHGO ;  Q9C104, GDE1_SCHPO ;  Q02979, GDE1_YEAST ;
DR   Q9FJ62, GLPQ1_ARATH;  P96236, GLPQ1_MYCTU;  Q9SZ11, GLPQ2_ARATH;
DR   Q7Y208, GLPQ3_ARATH;  P37965, GLPQ_BACSU ;  P09394, GLPQ_ECOLI ;
DR   Q06282, GLPQ_HAEIN ;  O30405, GLPQ_TREPA ;  P10908, UGPQ_ECOLI ;
DR   O07592, YHDW_BACSU ;
//
ID   3.1.4.47
DE   Transferred entry: 4.6.1.14.
//
ID   3.1.4.48
DE   Dolichylphosphate-glucose phosphodiesterase.
CA   Dolichyl beta-D-glucosyl phosphate + H(2)O = dolichyl phosphate +
CA   D-glucose.
//
ID   3.1.4.49
DE   Dolichylphosphate-mannose phosphodiesterase.
AN   Mannosylphosphodolichol phosphodiesterase.
CA   Dolichyl beta-D-mannosyl phosphate + H(2)O = dolichyl phosphate +
CA   D-mannose.
//
ID   3.1.4.50
DE   Glycosylphosphatidylinositol phospholipase D.
AN   Glycoprotein phospholipase D.
AN   GPI-PLD.
AN   Phosphatidylinositol phospholipase D.
AN   Phosphatidylinositol-glycan-specific phospholipase D.
AN   Phosphatidylinositol-specific phospholipase D.
CA   6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H(2)O =
CA   6-(alpha-D-glucosaminyl)-1D-myo-inositol + phosphatidate.
CC   -!- This enzyme is also active when O-4 of the glucosamine is substituted
CC       by carrying the oligosaccharide that can link a protein to the
CC       structure.
CC   -!- It therefore cleaves proteins from the lipid part of the
CC       glycosylphosphatidylinositol (GPI) anchors, but does so by
CC       hydrolysis, whereas EC 4.6.1.14 does so by elimination.
CC   -!- It acts on plasma membranes only after solubilization of the
CC       substrate with detergents or solvents, but it may act on
CC       intracellular membranes.
DR   P80109, PHLD_BOVIN ;  P80108, PHLD_HUMAN ;  O70362, PHLD_MOUSE ;
DR   Q8R2H5, PHLD_RAT   ;  Q86AV9, PLDG_DICDI ;
//
ID   3.1.4.51
DE   Glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase.
AN   Alpha-glucose-1-phosphate phosphodiesterase.
CA   6-(D-glucose-1-phospho)-D-mannosylglycoprotein + H(2)O = alpha-D-glucose
CA   1-phosphate + D-mannosylglycoprotein.
CC   -!- This enzyme is specific for the product of EC 2.7.8.19.
//
ID   3.1.4.52
DE   Cyclic-guanylate-specific phosphodiesterase.
AN   C-di-GMP-specific phosphodiesterase.
AN   PDEA1.
AN   Phosphodiesterase A1.
CA   Cyclic di-3',5'-guanylate + H(2)O = 5'-phosphoguanylyl(3'->5')guanosine.
CF   Heme; Magnesium; Manganese.
CC   -!- Inhibited by Ca(2+) and Zn(2+).
CC   -!- Linearizes cyclic di-3',5'-guanylate, the product of EC 2.7.7.65 and
CC       an allosteric activator of EC 2.4.1.12 rendering it inactive.
CC   -!- It is the balance between these two enzymes that determines the
CC       cellular level of cyclic di-3',5'-guanylate.
DR   P76261, ADRB_ECOLI ;  P76129, DOSP_ECOLI ;  P77334, GMR_ECOLI  ;
DR   Q4UU85, RPFG_XANC8 ;  P77172, YFGF_ECOLI ;  P37646, YHJH_ECOLI ;
DR   P75800, YLIE_ECOLI ;
//
ID   3.1.4.53
DE   3',5'-cyclic-AMP phosphodiesterase.
AN   cAMP-specific PDE.
AN   cAMP-specific phosphodiesterase.
CA   Adenosine 3',5'-cyclic phosphate + H(2)O = adenosine 5'-phosphate.
CC   -!- Specific for 3',5'-cAMP and does not hydrolyze other nucleoside
CC       3',5'-cyclic phosphates such as cGMP (cf. EC 3.1.4.17 and
CC       EC 3.1.4.35).
CC   -!- It is involved in modulation of the levels of cAMP, which is a
CC       mediator in the processes of cell transformation and proliferation.
CC   -!- Formerly EC 3.1.4.n1.
PR   PROSITE; PDOC00116;
DR   P12019, PDE1_DICDI ;  Q23917, PDE2_DICDI ;  Q86H13, PDE4_DICDI ;
DR   Q8MM62, PDE6_DICDI ;  Q54HY0, PDE7_DICDI ;
//
ID   3.1.4.n1
DE   Transferred entry: 3.1.4.53.
//
ID   3.1.5.1
DE   dGTPase.
AN   Deoxy-GTPase.
AN   Deoxyguanosinetriphosphate triphosphohydrolase.
CA   dGTP + H(2)O = deoxyguanosine + triphosphate.
CC   -!- Also acts on GTP.
DR   Q59435, DGTP2_ESCF3;  A8ALC8, DGTP_CITK8 ;  A7ZHQ2, DGTP_ECO24 ;
DR   B7UIK7, DGTP_ECO27 ;  B7MBE3, DGTP_ECO45 ;  B7LGM2, DGTP_ECO55 ;
DR   Q8X8Y9, DGTP_ECO57 ;  B5Z0E0, DGTP_ECO5E ;  B7NIC3, DGTP_ECO7I ;
DR   B7MP22, DGTP_ECO81 ;  B7M1A1, DGTP_ECO8A ;  C4ZRQ3, DGTP_ECOBW ;
DR   B1XD30, DGTP_ECODH ;  A7ZWA8, DGTP_ECOHS ;  A1A7K6, DGTP_ECOK1 ;
DR   Q0TLH1, DGTP_ECOL5 ;  Q8FL13, DGTP_ECOL6 ;  B1IQI0, DGTP_ECOLC ;
DR   P15723, DGTP_ECOLI ;  B7N829, DGTP_ECOLU ;  B6HZD6, DGTP_ECOSE ;
DR   B1LGW3, DGTP_ECOSM ;  Q1RG28, DGTP_ECOUT ;  A4W6Q7, DGTP_ENT38 ;
DR   A7MGS4, DGTP_ENTS8 ;  B7LWC1, DGTP_ESCF3 ;  B5Y1K9, DGTP_KLEP3 ;
DR   A6T4W4, DGTP_KLEP7 ;  Q9I4L1, DGTP_PSEAE ;  A9MPK1, DGTP_SALAR ;
DR   Q57T47, DGTP_SALCH ;  B5R3H2, DGTP_SALEP ;  B5RHE6, DGTP_SALG2 ;
DR   Q5PD54, DGTP_SALPA ;  B5BL88, DGTP_SALPK ;  B4TXR2, DGTP_SALSV ;
DR   Q8Z9B1, DGTP_SALTI ;  P40733, DGTP_SALTY ;  A8G9V4, DGTP_SERP5 ;
DR   B2U304, DGTP_SHIB3 ;  Q59827, DGTP_SHIBO ;  Q325X9, DGTP_SHIBS ;
DR   Q0T846, DGTP_SHIF8 ;  Q83MD6, DGTP_SHIFL ;  A1JJQ7, DGTP_YERE8 ;
DR   A7FM03, DGTP_YERP3 ;  Q1C3X8, DGTP_YERPA ;  B2K554, DGTP_YERPB ;
DR   Q8ZBM5, DGTP_YERPE ;  A9R1D9, DGTP_YERPG ;  Q1CLU0, DGTP_YERPN ;
DR   A4TPX3, DGTP_YERPP ;  Q66EE5, DGTP_YERPS ;  B1JK16, DGTP_YERPY ;
//
ID   3.1.6.1
DE   Arylsulfatase.
AN   Aryl-sulfate sulphohydrolase.
AN   Sulfatase.
CA   A phenol sulfate + H(2)O = a phenol + sulfate.
CC   -!- A group of enzymes with rather similar specificities.
PR   PROSITE; PDOC00117;
DR   P28607, ARS_ALTCA  ;  P14217, ARS_CHLRE  ;  P14000, ARS_HEMPU  ;
DR   P51691, ARS_PSEAE  ;  P50473, ARS_STRPU  ;  Q10723, ARS_VOLCA  ;
DR   P25549, ASLA_ECOLI ;  P20713, ATSA_ENTAE ;  Q9X759, ATSA_KLEPN ;
DR   Q0TUK6, SULF_CLOP1 ;  Q8XNV1, SULF_CLOPE ;
//
ID   3.1.6.2
DE   Steryl-sulfatase.
AN   Arylsulfatase C.
AN   Steroid sulfatase.
AN   Steryl-sulfate sulfohydrolase.
CA   3-beta-hydroxyandrost-5-en-17-one 3-sulfate + H(2)O = 3-beta-
CA   hydroxyandrost-5-en-17-one + sulfate.
CC   -!- Also acts on some related steryl sulfates.
PR   PROSITE; PDOC00117;
DR   P08842, STS_HUMAN  ;  P50427, STS_MOUSE  ;  P15589, STS_RAT    ;
//
ID   3.1.6.3
DE   Glycosulfatase.
AN   Glucosulfatase.
CA   D-glucose 6-sulfate + H(2)O = D-glucose + sulfate.
CC   -!- Also acts on other sulfates of mono- and disaccharides and on
CC       adenosine 5'-sulfate.
//
ID   3.1.6.4
DE   N-acetylgalactosamine-6-sulfatase.
AN   Chondroitinase.
AN   Chondroitinsulfatase.
AN   Galactose-6-sulfate sulfatase.
CA   Hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine
CA   6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate
CA   units of keratan sulfate.
PR   PROSITE; PDOC00117;
DR   Q32KH5, GALNS_CANFA;  P34059, GALNS_HUMAN;  Q571E4, GALNS_MOUSE;
DR   Q8WNQ7, GALNS_PIG  ;  Q32KJ6, GALNS_RAT  ;
//
ID   3.1.6.5
DE   Deleted entry.
//
ID   3.1.6.6
DE   Choline-sulfatase.
CA   Choline sulfate + H(2)O = choline + sulfate.
DR   O69787, BETC_RHIME ;
//
ID   3.1.6.7
DE   Cellulose-polysulfatase.
CA   Hydrolysis of the 2- and 3-sulfate groups of the polysulfates of
CA   cellulose and charonin.
//
ID   3.1.6.8
DE   Cerebroside-sulfatase.
AN   Arylsulfatase A.
CA   A cerebroside 3-sulfate + H(2)O = a cerebroside + sulfate.
CC   -!- Hydrolyzes galactose-3-sulfate residues in a number of lipids.
CC   -!- Also hydrolyzes ascorbate 2-sulfate and many phenol sulfates.
PR   PROSITE; PDOC00117;
DR   Q08DD1, ARSA_BOVIN ;  P15289, ARSA_HUMAN ;  P50428, ARSA_MOUSE ;
//
ID   3.1.6.9
DE   Chondro-4-sulfatase.
CA   4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine
CA   4-sulfate + H(2)O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-
CA   galactosamine + sulfate.
CC   -!- Also acts on the saturated analog but not on higher oligosaccharides,
CC       nor any 6-sulfates.
//
ID   3.1.6.10
DE   Chondro-6-sulfatase.
CA   4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine
CA   6-sulfate + H(2)O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-
CA   galactosamine + sulfate.
CC   -!- Also acts on the saturated analog and N-acetyl-D-galactosamine 4,6-
CC       disulfate, but not higher oligosaccharides, nor any 4-sulfate.
//
ID   3.1.6.11
DE   Disulfoglucosamine-6-sulfatase.
AN   N-sulfoglucosamine-6-sulfatase.
CA   2-N,6-O-disulfo-D-glucosamine + H(2)O = 2-N-sulfo-D-glucosamine +
CA   sulfate.
CC   -!- May be identical with EC 3.1.6.14.
//
ID   3.1.6.12
DE   N-acetylgalactosamine-4-sulfatase.
AN   Arylsulfatase B.
AN   Chondroitinase.
AN   Chondroitinsulfatase.
CA   Hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine
CA   4-sulfate units of chondroitin sulfate and dermatan sulfate.
CC   -!- Also acts on N-acetylglucosamine 4-sulfate.
PR   PROSITE; PDOC00117;
DR   P33727, ARSB_FELCA ;  P15848, ARSB_HUMAN ;  P50429, ARSB_MOUSE ;
DR   P50430, ARSB_RAT   ;
//
ID   3.1.6.13
DE   Iduronate-2-sulfatase.
AN   Chondroitinsulfatase.
CA   Hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of
CA   dermatan sulfate, heparan sulfate and heparin.
PR   PROSITE; PDOC00117;
DR   P22304, IDS_HUMAN  ;  Q08890, IDS_MOUSE  ;
//
ID   3.1.6.14
DE   N-acetylglucosamine-6-sulfatase.
AN   Chondroitinsulfatase.
AN   Glucosamine-6-sulfatase.
CA   Hydrolysis of the 6-sulfate groups of the N-acetyl-D-glucosamine
CA   6-sulfate units of heparan sulfate and keratan sulfate.
CC   -!- May be identical with EC 3.1.6.11.
PR   PROSITE; PDOC00117;
DR   Q1LZH9, GNS_BOVIN  ;  P50426, GNS_CAPHI  ;  P15586, GNS_HUMAN  ;
DR   Q8BFR4, GNS_MOUSE  ;
//
ID   3.1.6.15
DE   N-sulfoglucosamine-3-sulfatase.
AN   Chondroitinsulfatase.
CA   Hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-
CA   sulfate units of heparin.
CC   -!- The enzyme from Flavobacterium heparinum also hydrolyzes N-acetyl-D-
CC       glucosamine 3-O-sulfate; the mammalian enzyme acts only on the
CC       disulfated residue.
//
ID   3.1.6.16
DE   Monomethyl-sulfatase.
CA   Monomethyl sulfate + H(2)O = methanol + sulfate.
CC   -!- Highly specific; does not act on monoethyl sulfate, monoisopropyl
CC       sulfate or monododecyl sulfate.
//
ID   3.1.6.17
DE   D-lactate-2-sulfatase.
CA   (R)-2-O-sulfolactate + H(2)O = (R)-lactate + sulfate.
CC   -!- Highly specific.
//
ID   3.1.6.18
DE   Glucuronate-2-sulfatase.
AN   Chondro-2-sulfatase.
CA   Hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate
CA   residues of chondroitin sulfate, heparin and heparitin sulfate.
CC   -!- Does not act on iduronate 2-sulfate residues (cf. EC 3.1.6.13).
//
ID   3.1.7.1
DE   Prenyl-diphosphatase.
AN   Prenyl-pyrophosphatase.
CA   Prenyl diphosphate + H(2)O = prenol + diphosphate.
CC   -!- Farnesyl diphosphate is the best substrate so far tested.
//
ID   3.1.7.2
DE   Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase.
AN   (ppGpp)ase.
AN   Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase.
AN   Penta-phosphate guanosine-3'-diphosphohydrolase.
AN   Penta-phosphate guanosine-3'-pyrophosphohydrolase.
CA   Guanosine 3',5'-bis(diphosphate) + H(2)O = guanosine 5'-diphosphate +
CA   diphosphate.
DR   Q568P1, MESH1_DANRE;  Q9VAM9, MESH1_DROME;  Q8N4P3, MESH1_HUMAN;
DR   Q9D114, MESH1_MOUSE;  Q28C98, MESH1_XENTR;  P66014, RELA_MYCTU ;
DR   Q54089, RELA_STREQ ;  O67012, SPOT_AQUAE ;  O51216, SPOT_BORBU ;
DR   P0AG25, SPOT_ECO57 ;  P0AG24, SPOT_ECOLI ;  P43811, SPOT_HAEIN ;
DR   P47520, SPOT_MYCGE ;  P75386, SPOT_MYCPN ;  P0AG26, SPOT_SHIFL ;
DR   O34098, SPOT_SPICI ;  P74007, SPOT_SYNY3 ;  Q9KNM2, SPOT_VIBCH ;
//
ID   3.1.7.3
DE   Monoterpenyl-diphosphatase.
AN   Bornyl diphosphate hydrolase.
AN   Bornyl pyrophosphate hydrolase.
AN   Monoterpenyl-pyrophosphatase.
CA   A monoterpenyl diphosphate + H(2)O = a monoterpenol + diphosphate.
CC   -!- A group of enzymes with varying specificity for the monoterpenol
CC       moiety.
CC   -!- One has highest activity on sterically-hindered compounds such as
CC       (+)-bornyl diphosphate; another has highest activity on the
CC       diphosphates of primary alylic alcohols such as geraniol.
//
ID   3.1.7.4
DE   Sclareol cyclase.
AN   Geranylgeranyl pyrophosphate-sclareol cyclase.
CA   Geranylgeranyl diphosphate + 2 H(2)O = sclareol + diphosphate.
CF   Manganese or magnesium.
CC   -!- Sclareol, a labdane diterpene, is a plant secondary metabolite that
CC       exhibits potent antibacterial activity as well as fungal-growth-
CC       regulating and plant-growth-inhibiting properties.
CC   -!- It also exhibits cytotoxic activity against human leukaemic cell
CC       lines by inducing apoptosis.
//
ID   3.1.7.5
DE   Geranylgeranyl diphosphate diphosphatase.
AN   Geranylgeranyl diphosphate phosphatase.
CA   Geranylgeranyl diphosphate + H(2)O = geranylgeraniol + diphosphate.
CC   -!- Involved in the biosynthesis of plaunotol.
CC   -!- There are two isoenzymes with different ion requirements.
CC   -!- Neither require Mg(2+) but in addition PII is inhibited by Zn(2+),
CC       Mn(2+) and Co(2+).
CC   -!- It is not known which isoenzyme is involved in plaunotol
CC       biosynthesis.
//
ID   3.1.7.6
DE   Farnesyl diphosphatase.
AN   FPP phosphatase.
CA   (2E,6E)-farnesyl diphosphate + H(2)O = (2E,6E)-farnesol + diphosphate.
CC   -!- The enzyme is involved in the biosynthesis of acyclic
CC       sesquiterpenoids.
DR   Q84ZW8, ACSS_MAIZE ;  P11491, PPB_YEAST  ;
//
ID   3.1.7.7
DE   Drimenol cyclase.
AN   Farnesyl pyrophosphate:drimenol cyclase.
CA   (2E,6E)-farnesyl diphosphate + H(2)O = drimenol + diphosphate.
//
ID   3.1.8.1
DE   Aryldialkylphosphatase.
AN   A-esterase.
AN   Aryltriphosphatase.
AN   Paraoxon hydrolase.
AN   Paraoxonase.
AN   Phosphotriesterase.
CA   An aryl dialkyl phosphate + H(2)O = dialkyl phosphate + an aryl alcohol.
CF   Divalent cation.
CC   -!- Acts on organophosphorus compounds (such as paraoxon) including
CC       esters of phosphonic and phosphinic acids.
CC   -!- Inhibited by chelating agents.
CC   -!- Previously regarded as identical with EC 3.1.1.2.
PR   PROSITE; PDOC01026;
DR   P0A434, OPD_BREDI  ;  P0A433, OPD_FLAS2  ;  Q44238, PEPQ_ALTSX ;
DR   Q97VT7, PHP_SULSO  ;  P27169, PON1_HUMAN ;  P52430, PON1_MOUSE ;
DR   P27170, PON1_RABIT ;  P55159, PON1_RAT   ;  Q90952, PON2_CHICK ;
DR   Q91090, PON2_MELGA ;  Q15166, PON3_HUMAN ;  Q62087, PON3_MOUSE ;
DR   Q9BGN0, PON3_RABIT ;  Q68FP2, PON3_RAT   ;
//
ID   3.1.8.2
DE   Diisopropyl-fluorophosphatase.
AN   DFPase.
AN   OPA anhydrase.
AN   OPAA.
AN   Organophosphorus acid anhydrolase.
AN   Somanase.
AN   Tabunase.
CA   Diisopropyl fluorophosphate + H(2)O = diisopropyl phosphate + fluoride.
CF   Divalent cation.
CC   -!- Acts on phosphorus anhydride bonds (such as phosphorus-halide and
CC       phosphorus-cyanide) in organophosphorus compounds (including nerve
CC       gases).
CC   -!- Inhibited by chelating agents.
CC   -!- Related to EC 3.1.8.1.
CC   -!- Formerly EC 3.8.2.1.
DR   Q7SIG4, DFPA_LOLVU ;  Q44238, PEPQ_ALTSX ;  P77814, PEPQ_PSEHA ;
//
ID   3.1.11.1
DE   Exodeoxyribonuclease I.
AN   E.coli exonuclease I.
AN   Exonuclease I.
CA   Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside
CA   5'-phosphates.
CC   -!- Preference for single-stranded DNA.
CC   -!- The Escherichia coli enzyme hydrolyzes glucosylated DNA.
CC   -!- Similar enzymes; mammalian DNase III, exonuclease IV, T2- and
CC       T4-induced exodeoxyribonucleases.
CC   -!- Formerly EC 3.1.4.25.
DR   P57620, EX1_BUCAI  ;  Q8K923, EX1_BUCAP  ;  Q89A43, EX1_BUCBP  ;
DR   P04995, EX1_ECOLI  ;  P45188, EX1_HAEIN  ;  P04536, EXOD_BPT4  ;
//
ID   3.1.11.2
DE   Exodeoxyribonuclease III.
AN   E.coli exonuclease III.
AN   Exonuclease III.
CA   Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside
CA   5'-phosphates.
CC   -!- Preference for double-stranded DNA.
CC   -!- Has endonucleolytic activity near apurinic sites on DNA.
CC   -!- Similar enzyme: Haemophilus influenzae exonuclease.
CC   -!- Formerly EC 3.1.4.27.
PR   PROSITE; PDOC00598;
DR   P09030, EX3_ECOLI  ;  P44318, EX3_HAEIN  ;  P0A1B0, EX3_SALTI  ;
DR   P0A1A9, EX3_SALTY  ;  P37454, EXOA_BACSU ;  P0A2X3, EXOA_STRPN ;
DR   P0A2X4, EXOA_STRR6 ;  O60671, RAD1_HUMAN ;  Q9QWZ1, RAD1_MOUSE ;
DR   Q5R7X9, RAD1_PONAB ;  Q99638, RAD9A_HUMAN;  Q4R5X9, RAD9A_MACFA;
DR   Q9Z0F6, RAD9A_MOUSE;  P14746, REC1_USTMA ;  Q9BG99, TREX1_BOVIN;
DR   Q9NSU2, TREX1_HUMAN;  Q91XB0, TREX1_MOUSE;  Q9BQ50, TREX2_HUMAN;
DR   Q9R1A9, TREX2_MOUSE;
//
ID   3.1.11.3
DE   Exodeoxyribonuclease (lambda-induced).
AN   Lambda exonuclease.
CA   Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside
CA   5'-phosphates.
CC   -!- Preference for double-stranded DNA.
CC   -!- Does not attack single-strand breaks.
CC   -!- Similar enzymes: T4, T5 and T7 exonucleases, mammalian DNase IV.
CC   -!- Formerly EC 3.1.4.28.
DR   P06229, EXO5_BPT5  ;  P03697, EXO_LAMBD  ;  P20321, EXRN_BPT3  ;
DR   P00638, EXRN_BPT7  ;
//
ID   3.1.11.4
DE   Exodeoxyribonuclease (phage SP3-induced).
AN   DNA 5'-dinucleotidohydrolase.
AN   Phage SP3 DNase.
CA   Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside
CA   5'-phosphates.
CC   -!- Preference for single-stranded DNA.
CC   -!- Formerly EC 3.1.4.31.
//
ID   3.1.11.5
DE   Exodeoxyribonuclease V.
AN   E.coli exonuclease V.
AN   Exonuclease V.
CA   Exonucleolytic cleavage (in the presence of ATP) in either 5'- to 3'- or
CA   3'- to 5'-direction to yield 5'-phosphooligonucleotides.
CC   -!- Preference for double-stranded DNA.
CC   -!- Possesses DNA-dependent ATPase activity.
CC   -!- Acts endonucleolytically on single-stranded circular DNA.
CC   -!- Similar enzyme: Haemophilus influenzae ATP-dependent DNase.
DR   P57530, EX5A_BUCAI ;  Q8K9A8, EX5A_BUCAP ;  Q89AB2, EX5A_BUCBP ;
DR   P04993, EX5A_ECOLI ;  P45158, EX5A_HAEIN ;  P96919, EX5A_MYCTU ;
DR   O51578, EX5B_BORBU ;  P57529, EX5B_BUCAI ;  Q8K9A9, EX5B_BUCAP ;
DR   Q89AB3, EX5B_BUCBP ;  Q9PLT8, EX5B_CHLMU ;  Q9Z7G7, EX5B_CHLPN ;
DR   O84645, EX5B_CHLTR ;  P08394, EX5B_ECOLI ;  P45157, EX5B_HAEIN ;
DR   P96920, EX5B_MYCTU ;  P57528, EX5C_BUCAI ;  Q8K9B0, EX5C_BUCAP ;
DR   Q89AB4, EX5C_BUCBP ;  P07648, EX5C_ECOLI ;  P44945, EX5C_HAEIN ;
DR   P96921, EX5C_MYCTU ;
//
ID   3.1.11.6
DE   Exodeoxyribonuclease VII.
AN   E.coli exonuclease VII.
AN   Exonuclease VII.
CA   Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to
CA   yield nucleoside 5'-phosphates.
CC   -!- Preference for single-stranded DNA.
CC   -!- Similar enzyme: Micrococcus luteus exonuclease.
DR   B0BZ38, EX7L_ACAM1 ;  A9NFG5, EX7L_ACHLI ;  Q1IV16, EX7L_ACIBL ;
DR   A0LW37, EX7L_ACIC1 ;  Q8UIM4, EX7L_AGRT5 ;  B9JYI6, EX7L_AGRVS ;
DR   Q0VNE8, EX7L_ALCBS ;  B6EGZ4, EX7L_ALISL ;  A6TR38, EX7L_ALKMQ ;
DR   A8MFJ1, EX7L_ALKOO ;  B9KHB8, EX7L_ANAMF ;  Q5P9B4, EX7L_ANAMM ;
DR   Q2GIH0, EX7L_ANAPZ ;  A8I6A9, EX7L_AZOC5 ;  C1DE08, EX7L_AZOVD ;
DR   C3P7V9, EX7L_BACAA ;  C3LJV4, EX7L_BACAC ;  A0RIH2, EX7L_BACAH ;
DR   Q81M51, EX7L_BACAN ;  B7JM31, EX7L_BACC0 ;  Q731B3, EX7L_BACC1 ;
DR   B7IXH1, EX7L_BACC2 ;  C1ERQ3, EX7L_BACC3 ;  B7HB51, EX7L_BACC4 ;
DR   B7HNU3, EX7L_BACC7 ;  A7GSJ8, EX7L_BACCN ;  B9IXH3, EX7L_BACCQ ;
DR   Q818R6, EX7L_BACCR ;  Q635A4, EX7L_BACCZ ;  Q9K967, EX7L_BACHD ;
DR   Q6HDY5, EX7L_BACHK ;  Q65HI9, EX7L_BACLD ;  A8FF14, EX7L_BACP2 ;
DR   Q5WF60, EX7L_BACSK ;  P54521, EX7L_BACSU ;  A9VGD4, EX7L_BACWK ;
DR   A1UTK7, EX7L_BARBK ;  Q6G2I3, EX7L_BARHE ;  Q6FZ30, EX7L_BARQU ;
DR   A9IXA1, EX7L_BART1 ;  B2IJK8, EX7L_BEII9 ;  Q2KZF3, EX7L_BORA1 ;
DR   Q7WKU2, EX7L_BORBR ;  Q7W7F4, EX7L_BORPA ;  Q7VVB6, EX7L_BORPE ;
DR   Q89DD2, EX7L_BRAJA ;  C0ZC06, EX7L_BREBN ;  B2SAR1, EX7L_BRUA1 ;
DR   Q2YL15, EX7L_BRUA2 ;  Q578P4, EX7L_BRUAB ;  A9MC50, EX7L_BRUC2 ;
DR   C0RLR7, EX7L_BRUMB ;  Q8YCK1, EX7L_BRUME ;  A5VV55, EX7L_BRUO2 ;
DR   A9WZ60, EX7L_BRUSI ;  Q8FVR1, EX7L_BRUSU ;  A0RMM6, EX7L_CAMFF ;
DR   A7I2V3, EX7L_CAMHC ;  A8FKB4, EX7L_CAMJ8 ;  A7H544, EX7L_CAMJD ;
DR   Q9PIH4, EX7L_CAMJE ;  A1VY44, EX7L_CAMJJ ;  Q5HWE6, EX7L_CAMJR ;
DR   B9KDM8, EX7L_CAMLR ;  Q3AAM5, EX7L_CARHZ ;  B8GYM1, EX7L_CAUCN ;
DR   Q9A649, EX7L_CAUCR ;  B0SY33, EX7L_CAUSK ;  Q5L6H1, EX7L_CHLAB ;
DR   Q823U8, EX7L_CHLCV ;  Q253S0, EX7L_CHLFF ;  Q9PK65, EX7L_CHLMU ;
DR   Q9Z6J7, EX7L_CHLPN ;  B0B7P6, EX7L_CHLT2 ;  Q3KM31, EX7L_CHLTA ;
DR   B0BBW1, EX7L_CHLTB ;  Q8KBF9, EX7L_CHLTE ;  O84333, EX7L_CHLTR ;
DR   A8AD78, EX7L_CITK8 ;  A5CT74, EX7L_CLAM3 ;  B0RH22, EX7L_CLAMS ;
DR   Q97HD0, EX7L_CLOAB ;  A7FUU0, EX7L_CLOB1 ;  C3KXC6, EX7L_CLOB6 ;
DR   A6LU45, EX7L_CLOB8 ;  B2V4R6, EX7L_CLOBA ;  B2TRM8, EX7L_CLOBB ;
DR   A5I309, EX7L_CLOBH ;  C1FPB2, EX7L_CLOBJ ;  B1IMN8, EX7L_CLOBK ;
DR   A7GEJ7, EX7L_CLOBL ;  B1KT53, EX7L_CLOBM ;  B8I3A9, EX7L_CLOCE ;
DR   Q18B66, EX7L_CLOD6 ;  B9E101, EX7L_CLOK1 ;  A5N7I9, EX7L_CLOK5 ;
DR   A0Q0A1, EX7L_CLONN ;  Q0TPD5, EX7L_CLOP1 ;  Q8XJD8, EX7L_CLOPE ;
DR   A9KMC1, EX7L_CLOPH ;  Q0SS02, EX7L_CLOPS ;  Q894G7, EX7L_CLOTE ;
DR   Q6NI37, EX7L_CORDI ;  Q8FQP1, EX7L_COREF ;  A4QCY8, EX7L_CORGB ;
DR   Q8NRM3, EX7L_CORGL ;  Q4JU84, EX7L_CORJK ;  Q475F5, EX7L_CUPPJ ;
DR   B8HMX6, EX7L_CYAP4 ;  Q9RXW9, EX7L_DEIRA ;  A9BWI7, EX7L_DELAS ;
DR   B1I3J0, EX7L_DESAP ;  Q24V00, EX7L_DESHY ;  B7UGU7, EX7L_ECO27 ;
DR   B7MHZ0, EX7L_ECO45 ;  B7LCP9, EX7L_ECO55 ;  Q8XAB0, EX7L_ECO57 ;
DR   B5Z0X8, EX7L_ECO5E ;  B7NQV5, EX7L_ECO7I ;  B7MYD7, EX7L_ECO81 ;
DR   B7M7L3, EX7L_ECO8A ;  C4ZX84, EX7L_ECOBW ;  B1XAY4, EX7L_ECODH ;
DR   A8A315, EX7L_ECOHS ;  A1AE45, EX7L_ECOK1 ;  Q0TEX9, EX7L_ECOL5 ;
DR   Q8FF64, EX7L_ECOL6 ;  B1IWF2, EX7L_ECOLC ;  P04994, EX7L_ECOLI ;
DR   B7N693, EX7L_ECOLU ;  B6I581, EX7L_ECOSE ;  B1LNG1, EX7L_ECOSM ;
DR   Q1R8M7, EX7L_ECOUT ;  C5BER7, EX7L_EDWI9 ;  A4WD84, EX7L_ENT38 ;
DR   Q836W6, EX7L_ENTFA ;  A7MGV1, EX7L_ENTS8 ;  Q6D286, EX7L_ERWCT ;
DR   B2VE96, EX7L_ERWT9 ;  Q2N6Q7, EX7L_ERYLH ;  B7LKD2, EX7L_ESCF3 ;
DR   B1YLQ2, EX7L_EXIS2 ;  C4L3F5, EX7L_EXISA ;  A8L188, EX7L_FRASN ;
DR   Q8REN3, EX7L_FUSNN ;  B5EI10, EX7L_GEOBB ;  Q75TC0, EX7L_GEOKA ;
DR   Q39UJ7, EX7L_GEOMG ;  B9M0X3, EX7L_GEOSF ;  Q74CA7, EX7L_GEOSL ;
DR   C6E2U7, EX7L_GEOSM ;  A5GF75, EX7L_GEOUR ;  Q4QNE5, EX7L_HAEI8 ;
DR   P43913, EX7L_HAEIN ;  Q0I3T0, EX7L_HAES1 ;  Q2SCJ1, EX7L_HAHCH ;
DR   B8D2H9, EX7L_HALOH ;  C4K5U1, EX7L_HAMD5 ;  Q17W89, EX7L_HELAH ;
DR   Q7VFE5, EX7L_HELHP ;  B6JKI8, EX7L_HELP2 ;  B5ZA25, EX7L_HELPG ;
DR   Q1CUP4, EX7L_HELPH ;  Q9ZMH7, EX7L_HELPJ ;  B2US91, EX7L_HELPS ;
DR   O25039, EX7L_HELPY ;  A4G7Y7, EX7L_HERAR ;  A6T178, EX7L_JANMA ;
DR   B5XNM2, EX7L_KLEP3 ;  A6TCC4, EX7L_KLEP7 ;  Q5FJG6, EX7L_LACAC ;
DR   Q038G0, EX7L_LACC3 ;  B3WEY3, EX7L_LACCB ;  Q1G9H2, EX7L_LACDA ;
DR   Q049N1, EX7L_LACDB ;  Q044H9, EX7L_LACGA ;  A8YVW9, EX7L_LACH4 ;
DR   Q74IM1, EX7L_LACJO ;  Q9CH84, EX7L_LACLA ;  A2RLU4, EX7L_LACLM ;
DR   Q88WM7, EX7L_LACPL ;  A5VKR6, EX7L_LACRD ;  B2G849, EX7L_LACRJ ;
DR   Q1WUJ2, EX7L_LACS1 ;  Q38XU8, EX7L_LACSS ;  Q5X6S7, EX7L_LEGPA ;
DR   A5IG90, EX7L_LEGPC ;  Q5ZXA6, EX7L_LEGPH ;  Q5WY82, EX7L_LEGPL ;
DR   Q6ADU9, EX7L_LEIXX ;  Q04TB1, EX7L_LEPBJ ;  Q051N3, EX7L_LEPBL ;
DR   Q72RZ7, EX7L_LEPIC ;  Q8F3P5, EX7L_LEPIN ;  Q92BZ3, EX7L_LISIN ;
DR   C1L2R7, EX7L_LISMC ;  Q71ZW1, EX7L_LISMF ;  Q8Y7C4, EX7L_LISMO ;
DR   A0AIG2, EX7L_LISW6 ;  B1HRX7, EX7L_LYSSC ;  Q6F1D5, EX7L_MESFL ;
DR   Q11LY8, EX7L_MESSB ;  Q2RIB5, EX7L_MOOTA ;  P67448, EX7L_MYCBO ;
DR   A1KHP8, EX7L_MYCBP ;  C1AMA2, EX7L_MYCBT ;  Q9X783, EX7L_MYCLE ;
DR   Q6MUD1, EX7L_MYCMS ;  Q73WH4, EX7L_MYCPA ;  A3Q4N2, EX7L_MYCSJ ;
DR   A1UKL7, EX7L_MYCSK ;  Q1B4H2, EX7L_MYCSS ;  A5U1F5, EX7L_MYCTA ;
DR   P67447, EX7L_MYCTU ;  B2A531, EX7L_NATTJ ;  B9L5W5, EX7L_NAUPA ;
DR   Q5F8V5, EX7L_NEIG1 ;  Q9JTY8, EX7L_NEIMA ;  Q9JYZ2, EX7L_NEIMB ;
DR   A1KUI5, EX7L_NEIMF ;  Q0AFX7, EX7L_NITEC ;  Q82VC2, EX7L_NITEU ;
DR   A6Q232, EX7L_NITSB ;  Q5YQ92, EX7L_NOCFA ;  A1SFK7, EX7L_NOCSJ ;
DR   Q8YW42, EX7L_NOSS1 ;  Q8EQ44, EX7L_OCEIH ;  A6X3A0, EX7L_OCHA4 ;
DR   A7HQR0, EX7L_PARL1 ;  Q9CP86, EX7L_PASMU ;  C6DBG5, EX7L_PECCP ;
DR   Q03FZ4, EX7L_PEDPA ;  Q3A3Z3, EX7L_PELCD ;  Q7N3K2, EX7L_PHOLL ;
DR   Q6LU33, EX7L_PHOPR ;  B4EY61, EX7L_PROMH ;  Q48LY3, EX7L_PSE14 ;
DR   Q15R61, EX7L_PSEA6 ;  B7UXJ1, EX7L_PSEA8 ;  Q02RT0, EX7L_PSEAB ;
DR   Q9HXL8, EX7L_PSEAE ;  Q1I5K4, EX7L_PSEE4 ;  Q4K6V9, EX7L_PSEF5 ;
DR   C3K1K5, EX7L_PSEFS ;  Q3IHJ4, EX7L_PSEHT ;  Q3K7C5, EX7L_PSEPF ;
DR   Q88P26, EX7L_PSEPK ;  Q886X9, EX7L_PSESM ;  Q4ZX12, EX7L_PSEU2 ;
DR   A4VNV0, EX7L_PSEU5 ;  Q8XWE7, EX7L_RALSO ;  B3PYF6, EX7L_RHIE6 ;
DR   Q2KDI7, EX7L_RHIEC ;  Q1MMN0, EX7L_RHIL3 ;  Q987V3, EX7L_RHILO ;
DR   B5ZYC6, EX7L_RHILW ;  Q92SR7, EX7L_RHIME ;  C3MCQ9, EX7L_RHISN ;
DR   Q7UTZ9, EX7L_RHOBA ;  B6IXD4, EX7L_RHOCS ;  A3PGZ4, EX7L_RHOS1 ;
DR   Q3J5E0, EX7L_RHOS4 ;  A4WQ76, EX7L_RHOS5 ;  B9KM14, EX7L_RHOSK ;
DR   C3PPC7, EX7L_RICAE ;  A8GPH1, EX7L_RICAH ;  A8GXS3, EX7L_RICB8 ;
DR   Q1RK25, EX7L_RICBR ;  A8EZN6, EX7L_RICCK ;  Q92GU6, EX7L_RICCN ;
DR   Q4UMV4, EX7L_RICFE ;  Q9ZCP8, EX7L_RICPR ;  Q68W63, EX7L_RICTY ;
DR   A1AX20, EX7L_RUTMC ;  B5F187, EX7L_SALA4 ;  A9MHM3, EX7L_SALAR ;
DR   B5FR54, EX7L_SALDC ;  B5R571, EX7L_SALEP ;  B5RCY1, EX7L_SALG2 ;
DR   B4TD84, EX7L_SALHS ;  B4T0N9, EX7L_SALNS ;  Q5PI54, EX7L_SALPA ;
DR   A9N216, EX7L_SALPB ;  C0PYP2, EX7L_SALPC ;  B5BAZ3, EX7L_SALPK ;
DR   Q2S4K5, EX7L_SALRD ;  B4TR85, EX7L_SALSV ;  Q8Z4Q1, EX7L_SALTI ;
DR   Q8ZN58, EX7L_SALTY ;  A8GHV3, EX7L_SERP5 ;  A1S858, EX7L_SHEAM ;
DR   B8E9T2, EX7L_SHEB2 ;  A3D6V4, EX7L_SHEB5 ;  A6WQP2, EX7L_SHEB8 ;
DR   A9KWW8, EX7L_SHEB9 ;  Q12PS2, EX7L_SHEDO ;  Q085S6, EX7L_SHEFN ;
DR   B0TLJ2, EX7L_SHEHH ;  A3QCG8, EX7L_SHELP ;  Q8EC50, EX7L_SHEON ;
DR   A8H252, EX7L_SHEPA ;  A0KUK0, EX7L_SHESA ;  A8FY06, EX7L_SHESH ;
DR   Q0HKV4, EX7L_SHESM ;  Q0HX52, EX7L_SHESR ;  B1KLB9, EX7L_SHEWM ;
DR   B2TXT4, EX7L_SHIB3 ;  Q31XY1, EX7L_SHIBS ;  Q32D53, EX7L_SHIDS ;
DR   Q0T210, EX7L_SHIF8 ;  Q83QL0, EX7L_SHIFL ;  Q3YZ43, EX7L_SHISS ;
DR   Q5LTR9, EX7L_SILPO ;  Q1GF88, EX7L_SILST ;  A6UF86, EX7L_SINMW ;
DR   Q2NS50, EX7L_SODGM ;  A7X2Q2, EX7L_STAA1 ;  A6U1Z5, EX7L_STAA2 ;
DR   Q2FGL0, EX7L_STAA3 ;  Q2FY46, EX7L_STAA8 ;  A5IT52, EX7L_STAA9 ;
DR   Q2YYB8, EX7L_STAAB ;  Q5HFP8, EX7L_STAAC ;  A6QH68, EX7L_STAAE ;
DR   P67449, EX7L_STAAM ;  P67450, EX7L_STAAN ;  Q6GGH5, EX7L_STAAR ;
DR   Q6G942, EX7L_STAAS ;  A8Z463, EX7L_STAAT ;  P67451, EX7L_STAAW ;
DR   B9DNP9, EX7L_STACT ;  Q5HP29, EX7L_STAEQ ;  Q8CP38, EX7L_STAES ;
DR   Q4L6M4, EX7L_STAHJ ;  Q49XW8, EX7L_STAS1 ;  Q3K2M4, EX7L_STRA1 ;
DR   Q8E6M1, EX7L_STRA3 ;  Q8E166, EX7L_STRA5 ;  Q82IE7, EX7L_STRAW ;
DR   Q9FBM3, EX7L_STRCO ;  B4U1W7, EX7L_STREM ;  A8AW35, EX7L_STRGC ;
DR   B1W2D9, EX7L_STRGG ;  B4SQC8, EX7L_STRM5 ;  B2FN41, EX7L_STRMK ;
DR   Q8DVB5, EX7L_STRMU ;  P67452, EX7L_STRP1 ;  Q04KB0, EX7L_STRP2 ;
DR   P0DH50, EX7L_STRP3 ;  B5E4U5, EX7L_STRP4 ;  Q5XB25, EX7L_STRP6 ;
DR   C1C7H6, EX7L_STRP7 ;  Q8P075, EX7L_STRP8 ;  A2RDN0, EX7L_STRPG ;
DR   B1IC09, EX7L_STRPI ;  B8ZQ76, EX7L_STRPJ ;  Q97QJ8, EX7L_STRPN ;
DR   P0DH51, EX7L_STRPQ ;  B5XM83, EX7L_STRPZ ;  Q8DPM9, EX7L_STRR6 ;
DR   A3CLQ7, EX7L_STRSV ;  Q5LZD9, EX7L_STRT1 ;  Q5M3Z1, EX7L_STRT2 ;
DR   Q03K98, EX7L_STRTD ;  B9DUT9, EX7L_STRU0 ;  C1CEH0, EX7L_STRZJ ;
DR   C1CKV3, EX7L_STRZP ;  C1CR91, EX7L_STRZT ;  Q30SS1, EX7L_SULDN ;
DR   Q7U490, EX7L_SYNPX ;  Q0I748, EX7L_SYNS3 ;  Q3AZZ0, EX7L_SYNS9 ;
DR   Q3AH76, EX7L_SYNSC ;  Q0AZF4, EX7L_SYNWW ;  Q47SR1, EX7L_THEFY ;
DR   A8F8T5, EX7L_THELT ;  Q9X289, EX7L_THEMA ;  A5ILK0, EX7L_THEP1 ;
DR   B0K9E1, EX7L_THEP3 ;  B0K0U8, EX7L_THEPX ;  B1LAQ5, EX7L_THESQ ;
DR   Q8RAC9, EX7L_THETN ;  Q3SIR1, EX7L_THIDA ;  B8GP32, EX7L_THISH ;
DR   C4L8C6, EX7L_TOLAT ;  Q83HE6, EX7L_TROW8 ;  Q83FR7, EX7L_TROWT ;
DR   A5CW49, EX7L_VESOH ;  A5F3E9, EX7L_VIBC3 ;  Q9KTW4, EX7L_VIBCH ;
DR   C3LT19, EX7L_VIBCM ;  Q5E765, EX7L_VIBF1 ;  B5FAX9, EX7L_VIBFM ;
DR   A7MU31, EX7L_VIBHB ;  Q87S09, EX7L_VIBPA ;  Q8DF05, EX7L_VIBVU ;
DR   Q7MNE3, EX7L_VIBVY ;  Q8PJW7, EX7L_XANAC ;  Q3BSC5, EX7L_XANC5 ;
DR   Q4UVP8, EX7L_XANC8 ;  B0RRZ3, EX7L_XANCB ;  Q8P8D9, EX7L_XANCP ;
DR   Q2P290, EX7L_XANOM ;  B2SHP3, EX7L_XANOP ;  Q5GZ80, EX7L_XANOR ;
DR   B2I9F0, EX7L_XYLF2 ;  Q9PFC3, EX7L_XYLFA ;  Q87AC5, EX7L_XYLFT ;
DR   A1JKT0, EX7L_YERE8 ;  A7FFZ6, EX7L_YERP3 ;  Q1C5J4, EX7L_YERPA ;
DR   B2K9P2, EX7L_YERPB ;  Q8ZCU2, EX7L_YERPE ;  A9R7Z4, EX7L_YERPG ;
DR   Q1CK84, EX7L_YERPN ;  A4TMT0, EX7L_YERPP ;  Q668A6, EX7L_YERPS ;
DR   B1JSA8, EX7L_YERPY ;  Q9FDL4, EX7L_ZYMMO ;  A0LW38, EX7S_ACIC1 ;
DR   A1W4U7, EX7S_ACISJ ;  A3N0G6, EX7S_ACTP2 ;  B3H1E5, EX7S_ACTP7 ;
DR   B0BP87, EX7S_ACTPJ ;  A6VP37, EX7S_ACTSZ ;  A4SJQ1, EX7S_AERS4 ;
DR   B9JAL9, EX7S_AGRRK ;  Q8UHD5, EX7S_AGRT5 ;  B9JSL3, EX7S_AGRVS ;
DR   B2UMV0, EX7S_AKKM8 ;  Q0AA37, EX7S_ALHEH ;  B6EIA9, EX7S_ALISL ;
DR   A6TR39, EX7S_ALKMQ ;  A8MFJ0, EX7S_ALKOO ;  Q2GLP1, EX7S_ANAPZ ;
DR   Q3MGJ7, EX7S_ANAVT ;  A0JYU5, EX7S_ARTS2 ;  A1K4R2, EX7S_AZOSB ;
DR   A7Z6J7, EX7S_BACA2 ;  C3P7V8, EX7S_BACAA ;  C3LJV3, EX7S_BACAC ;
DR   A0RIH1, EX7S_BACAH ;  Q81M52, EX7S_BACAN ;  B7JM30, EX7S_BACC0 ;
DR   Q731B4, EX7S_BACC1 ;  B7IXH0, EX7S_BACC2 ;  C1ERQ2, EX7S_BACC3 ;
DR   B7HB50, EX7S_BACC4 ;  B7HNU2, EX7S_BACC7 ;  A7GSJ7, EX7S_BACCN ;
DR   B9IXH2, EX7S_BACCQ ;  Q818R7, EX7S_BACCR ;  Q635A5, EX7S_BACCZ ;
DR   Q9K968, EX7S_BACHD ;  Q6HDY6, EX7S_BACHK ;  Q65HJ0, EX7S_BACLD ;
DR   A8FF13, EX7S_BACP2 ;  Q5WF61, EX7S_BACSK ;  P54522, EX7S_BACSU ;
DR   A9VGD3, EX7S_BACWK ;  A1URW5, EX7S_BARBK ;  Q6G4D2, EX7S_BARHE ;
DR   Q6G0D5, EX7S_BARQU ;  A9IQP0, EX7S_BART1 ;  Q6MR96, EX7S_BDEBA ;
DR   C5C0V6, EX7S_BEUC1 ;  Q7WL39, EX7S_BORBR ;  Q7W7Q2, EX7S_BORPA ;
DR   A9ITB6, EX7S_BORPD ;  Q7VV85, EX7S_BORPE ;  Q89RW0, EX7S_BRAJA ;
DR   A5EEQ1, EX7S_BRASB ;  A4YQ37, EX7S_BRASO ;  P67454, EX7S_BRUME ;
DR   P67455, EX7S_BRUSU ;  B1Z1G0, EX7S_BURA4 ;  Q1BLY5, EX7S_BURCA ;
DR   B1K3T1, EX7S_BURCC ;  A0AYY8, EX7S_BURCH ;  B4EN27, EX7S_BURCJ ;
DR   Q0BAM0, EX7S_BURCM ;  A9ANA4, EX7S_BURM1 ;  A3MBD0, EX7S_BURM7 ;
DR   A2S0N4, EX7S_BURM9 ;  Q62DU3, EX7S_BURMA ;  A1UYQ2, EX7S_BURMS ;
DR   A3P7W6, EX7S_BURP0 ;  A3NMF8, EX7S_BURP6 ;  Q63JF2, EX7S_BURPS ;
DR   Q393P2, EX7S_BURS3 ;  A4JLT2, EX7S_BURVG ;  Q3AAM6, EX7S_CARHZ ;
DR   B8GXC6, EX7S_CAUCN ;  Q9A6M3, EX7S_CAUCR ;  B0T3Y0, EX7S_CAUSK ;
DR   B3PF20, EX7S_CELJU ;  Q5L6H2, EX7S_CHLAB ;  Q823U9, EX7S_CHLCV ;
DR   Q253R9, EX7S_CHLFF ;  Q9PK64, EX7S_CHLMU ;  A1BJ57, EX7S_CHLPD ;
DR   Q9K1Y4, EX7S_CHLPN ;  B0B7P7, EX7S_CHLT2 ;  Q3KM30, EX7S_CHLTA ;
DR   B0BBW2, EX7S_CHLTB ;  Q8KAE9, EX7S_CHLTE ;  P58001, EX7S_CHLTR ;
DR   Q7NUK7, EX7S_CHRVO ;  A8AK32, EX7S_CITK8 ;  Q97HD1, EX7S_CLOAB ;
DR   A7FUT9, EX7S_CLOB1 ;  C3KXC5, EX7S_CLOB6 ;  A6LU46, EX7S_CLOB8 ;
DR   B2V4R5, EX7S_CLOBA ;  B2TRM7, EX7S_CLOBB ;  A5I308, EX7S_CLOBH ;
DR   C1FPB1, EX7S_CLOBJ ;  B1IMN7, EX7S_CLOBK ;  A7GEJ6, EX7S_CLOBL ;
DR   B1KT52, EX7S_CLOBM ;  B9E102, EX7S_CLOK1 ;  A5N7J0, EX7S_CLOK5 ;
DR   A0Q0A2, EX7S_CLONN ;  Q0TPD6, EX7S_CLOP1 ;  Q8XJD9, EX7S_CLOPE ;
DR   Q0SS03, EX7S_CLOPS ;  Q487D1, EX7S_COLP3 ;  C3PFD4, EX7S_CORA7 ;
DR   Q6NI38, EX7S_CORDI ;  B6J8G8, EX7S_COXB1 ;  B6J1L1, EX7S_COXB2 ;
DR   A9KEC8, EX7S_COXBN ;  A9NBV6, EX7S_COXBR ;  Q83E63, EX7S_COXBU ;
DR   Q47BJ2, EX7S_DECAR ;  C6BYY0, EX7S_DESAD ;  B8IZD4, EX7S_DESDA ;
DR   Q30Z97, EX7S_DESDG ;  Q24V01, EX7S_DESHY ;  C4XTC8, EX7S_DESMR ;
DR   Q6AJQ3, EX7S_DESPS ;  A4J3F7, EX7S_DESRM ;  Q72CD5, EX7S_DESVH ;
DR   A1VE71, EX7S_DESVV ;  A7ZIH5, EX7S_ECO24 ;  B7UJP5, EX7S_ECO27 ;
DR   B7MD80, EX7S_ECO45 ;  B7L656, EX7S_ECO55 ;  P0A8H1, EX7S_ECO57 ;
DR   B5Z3S7, EX7S_ECO5E ;  B7NJ75, EX7S_ECO7I ;  B7MQD7, EX7S_ECO81 ;
DR   B7M3R1, EX7S_ECO8A ;  C4ZTH9, EX7S_ECOBW ;  B1XF10, EX7S_ECODH ;
DR   A7ZX74, EX7S_ECOHS ;  Q0TKL9, EX7S_ECOL5 ;  P0A8H0, EX7S_ECOL6 ;
DR   B1J027, EX7S_ECOLC ;  P0A8G9, EX7S_ECOLI ;  B7N8X5, EX7S_ECOLU ;
DR   B6HZM5, EX7S_ECOSE ;  B1LJH2, EX7S_ECOSM ;  Q1RFB8, EX7S_ECOUT ;
DR   C5BCI1, EX7S_EDWI9 ;  B2KAR1, EX7S_ELUMP ;  A4W793, EX7S_ENT38 ;
DR   Q836W5, EX7S_ENTFA ;  A7MFH4, EX7S_ENTS8 ;  Q6D842, EX7S_ERWCT ;
DR   B2VHS1, EX7S_ERWT9 ;  B7LMG5, EX7S_ESCF3 ;  B0S1L9, EX7S_FINM2 ;
DR   B5EI11, EX7S_GEOBB ;  Q75TB9, EX7S_GEOKA ;  B3E479, EX7S_GEOLS ;
DR   Q39UA9, EX7S_GEOMG ;  B9M0X4, EX7S_GEOSF ;  Q74CA8, EX7S_GEOSL ;
DR   C6E2U6, EX7S_GEOSM ;  A4IQR9, EX7S_GEOTN ;  A5G3J6, EX7S_GEOUR ;
DR   A9HIR6, EX7S_GLUDA ;  Q5FUB3, EX7S_GLUOX ;  Q7VLU0, EX7S_HAEDU ;
DR   Q4QKG4, EX7S_HAEI8 ;  A5UC49, EX7S_HAEIE ;  A5UEV4, EX7S_HAEIG ;
DR   P43914, EX7S_HAEIN ;  B8F4R9, EX7S_HAEPS ;  A1WYI6, EX7S_HALHL ;
DR   C4K6M5, EX7S_HAMD5 ;  B0TEJ2, EX7S_HELMI ;  B6JNY0, EX7S_HELP2 ;
DR   B5Z9A1, EX7S_HELPG ;  Q1CRC4, EX7S_HELPH ;  Q9ZJD7, EX7S_HELPJ ;
DR   B2UVM8, EX7S_HELPS ;  O26016, EX7S_HELPY ;  A4G1W7, EX7S_HERAR ;
DR   Q5QVD9, EX7S_IDILO ;  A6SUS2, EX7S_JANMA ;  B5Y0W9, EX7S_KLEP3 ;
DR   A6T5F5, EX7S_KLEP7 ;  Q5FJG7, EX7S_LACAC ;  Q03RR3, EX7S_LACBA ;
DR   B2GD65, EX7S_LACF3 ;  Q044H8, EX7S_LACGA ;  A8YVW8, EX7S_LACH4 ;
DR   Q74IM2, EX7S_LACJO ;  Q9CH83, EX7S_LACLA ;  A2RLU3, EX7S_LACLM ;
DR   Q030A1, EX7S_LACLS ;  Q88WM6, EX7S_LACPL ;  A5VKR5, EX7S_LACRD ;
DR   B2G848, EX7S_LACRJ ;  Q38XU7, EX7S_LACSS ;  Q5X2W0, EX7S_LEGPA ;
DR   A5IEC9, EX7S_LEGPC ;  Q5ZT36, EX7S_LEGPH ;  Q5WUB9, EX7S_LEGPL ;
DR   Q6ADU8, EX7S_LEIXX ;  Q04TB2, EX7S_LEPBJ ;  Q051N4, EX7S_LEPBL ;
DR   Q72RZ8, EX7S_LEPIC ;  Q8F3P4, EX7S_LEPIN ;  B1MXR1, EX7S_LEUCK ;
DR   Q03VS7, EX7S_LEUMM ;  Q92BZ2, EX7S_LISIN ;  C1L2R8, EX7S_LISMC ;
DR   Q71ZW0, EX7S_LISMF ;  B8DFW6, EX7S_LISMH ;  Q8Y7C3, EX7S_LISMO ;
DR   A0AIG3, EX7S_LISW6 ;  B1HRX6, EX7S_LYSSC ;  Q2W369, EX7S_MAGSA ;
DR   A0L6H5, EX7S_MAGSM ;  Q65TP2, EX7S_MANSM ;  A6VUE7, EX7S_MARMS ;
DR   Q60AM9, EX7S_METCA ;  Q2RIB6, EX7S_MOOTA ;  A0QC35, EX7S_MYCA1 ;
DR   P67457, EX7S_MYCBO ;  A1KHP7, EX7S_MYCBP ;  C1AMA1, EX7S_MYCBT ;
DR   Q9X784, EX7S_MYCLE ;  B2HT44, EX7S_MYCMM ;  Q73WH3, EX7S_MYCPA ;
DR   A5U1F4, EX7S_MYCTA ;  P67456, EX7S_MYCTU ;  Q5F632, EX7S_NEIG1 ;
DR   Q9JSM1, EX7S_NEIMA ;  Q9K1A5, EX7S_NEIMB ;  A1KRU1, EX7S_NEIMF ;
DR   Q82VD5, EX7S_NITEU ;  Q1QQ39, EX7S_NITHX ;  Q3SUZ0, EX7S_NITWN ;
DR   Q5YQ91, EX7S_NOCFA ;  B2IWI8, EX7S_NOSP7 ;  Q8YW43, EX7S_NOSS1 ;
DR   Q2G632, EX7S_NOVAD ;  Q8EQ45, EX7S_OCEIH ;  B6JFI3, EX7S_OLICO ;
DR   Q6MDK5, EX7S_PARUW ;  Q8L1H9, EX7S_PARZE ;  Q9CNA0, EX7S_PASMU ;
DR   C6DB39, EX7S_PECCP ;  Q03FZ3, EX7S_PEDPA ;  A1ARP1, EX7S_PELPD ;
DR   A5D2Z3, EX7S_PELTS ;  B4RGV8, EX7S_PHEZH ;  Q7N0J8, EX7S_PHOLL ;
DR   Q6LU05, EX7S_PHOPR ;  A1VMD5, EX7S_POLNA ;  Q12CR1, EX7S_POLSJ ;
DR   Q6AA93, EX7S_PROAC ;  A6V060, EX7S_PSEA7 ;  B7V7R6, EX7S_PSEA8 ;
DR   Q02SK9, EX7S_PSEAB ;  Q9HWY5, EX7S_PSEAE ;  Q1IFK9, EX7S_PSEE4 ;
DR   Q4K5A7, EX7S_PSEF5 ;  C3K2Q9, EX7S_PSEFS ;  Q3II11, EX7S_PSEHT ;
DR   A5VXX1, EX7S_PSEP1 ;  Q3K662, EX7S_PSEPF ;  B0KL81, EX7S_PSEPG ;
DR   Q88QG5, EX7S_PSEPK ;  B1J3G6, EX7S_PSEPW ;  Q889P9, EX7S_PSESM ;
DR   Q4ZYU6, EX7S_PSEU2 ;  A1SWW4, EX7S_PSYIN ;  B2U932, EX7S_RALPJ ;
DR   Q8XX93, EX7S_RALSO ;  B3PS72, EX7S_RHIE6 ;  Q2KBQ9, EX7S_RHIEC ;
DR   Q985Y6, EX7S_RHILO ;  B5ZS73, EX7S_RHILW ;  Q92RI9, EX7S_RHIME ;
DR   Q7UWB5, EX7S_RHOBA ;  Q2IRL8, EX7S_RHOP2 ;  Q07SR2, EX7S_RHOP5 ;
DR   Q6NB75, EX7S_RHOPA ;  Q130G8, EX7S_RHOPS ;  B3QFY8, EX7S_RHOPT ;
DR   C3PN64, EX7S_RICAE ;  A8GN45, EX7S_RICAH ;  A8GWU6, EX7S_RICB8 ;
DR   Q1RIG7, EX7S_RICBR ;  A8EZ91, EX7S_RICCK ;  Q92IE5, EX7S_RICCN ;
DR   Q4UM15, EX7S_RICFE ;  A8F1C1, EX7S_RICM5 ;  Q9ZDH8, EX7S_RICPR ;
DR   C4K2Q1, EX7S_RICPU ;  B0BX65, EX7S_RICRO ;  A8GRQ8, EX7S_RICRS ;
DR   Q68X23, EX7S_RICTY ;  A1AWD0, EX7S_RUTMC ;  B5EXG5, EX7S_SALA4 ;
DR   A9MM40, EX7S_SALAR ;  Q57SE0, EX7S_SALCH ;  B5FKS9, EX7S_SALDC ;
DR   B5QTH2, EX7S_SALEP ;  B5R6S5, EX7S_SALG2 ;  B4T8R5, EX7S_SALHS ;
DR   B4SWR6, EX7S_SALNS ;  Q5PFR8, EX7S_SALPA ;  A9MX07, EX7S_SALPB ;
DR   C0Q7U9, EX7S_SALPC ;  B5BDA8, EX7S_SALPK ;  B4TMA4, EX7S_SALSV ;
DR   P67459, EX7S_SALTI ;  P67458, EX7S_SALTY ;  A8GAP4, EX7S_SERP5 ;
DR   B2U4M5, EX7S_SHIB3 ;  Q325H9, EX7S_SHIBS ;  Q32JI0, EX7S_SHIDS ;
DR   Q0T7G7, EX7S_SHIF8 ;  P0A8H2, EX7S_SHIFL ;  Q3Z4Y7, EX7S_SHISS ;
DR   Q5LX40, EX7S_SILPO ;  Q1GCG2, EX7S_SILST ;  A6U6S1, EX7S_SINMW ;
DR   Q2NV92, EX7S_SODGM ;  A7X2P9, EX7S_STAA1 ;  A6U1Z4, EX7S_STAA2 ;
DR   Q2FGL1, EX7S_STAA3 ;  Q2FY47, EX7S_STAA8 ;  A5IT51, EX7S_STAA9 ;
DR   Q2YYB9, EX7S_STAAB ;  Q5HFP9, EX7S_STAAC ;  P67460, EX7S_STAAM ;
DR   P67461, EX7S_STAAN ;  Q6GGH6, EX7S_STAAR ;  Q6G943, EX7S_STAAS ;
DR   A8Z462, EX7S_STAAT ;  P67462, EX7S_STAAW ;  Q5HP30, EX7S_STAEQ ;
DR   Q8CP39, EX7S_STAES ;  Q4L6M3, EX7S_STAHJ ;  Q3K2M3, EX7S_STRA1 ;
DR   P67463, EX7S_STRA3 ;  P67464, EX7S_STRA5 ;  Q82IE6, EX7S_STRAW ;
DR   Q9FBM4, EX7S_STRCO ;  C0M7V3, EX7S_STRE4 ;  B4U1W8, EX7S_STREM ;
DR   A8AW36, EX7S_STRGC ;  B4SQZ7, EX7S_STRM5 ;  B2FP36, EX7S_STRMK ;
DR   Q8DVB4, EX7S_STRMU ;  P67467, EX7S_STRP1 ;  Q04KB1, EX7S_STRP2 ;
DR   P0DH52, EX7S_STRP3 ;  B5E4U4, EX7S_STRP4 ;  Q5XB26, EX7S_STRP6 ;
DR   C1C7H5, EX7S_STRP7 ;  P67469, EX7S_STRP8 ;  Q1JAV6, EX7S_STRPB ;
DR   Q1JL06, EX7S_STRPC ;  Q1JG31, EX7S_STRPD ;  Q1J5U7, EX7S_STRPF ;
DR   A2RDN1, EX7S_STRPG ;  B1IC08, EX7S_STRPI ;  B8ZQ75, EX7S_STRPJ ;
DR   Q48SM9, EX7S_STRPM ;  P67465, EX7S_STRPN ;  P0DH53, EX7S_STRPQ ;
DR   B2IPS4, EX7S_STRPS ;  B5XM82, EX7S_STRPZ ;  P67466, EX7S_STRR6 ;
DR   A4W384, EX7S_STRS2 ;  C0MD33, EX7S_STRS7 ;  A3CLQ8, EX7S_STRSV ;
DR   A4VWY2, EX7S_STRSY ;  Q5LZE0, EX7S_STRT1 ;  Q5M3Z2, EX7S_STRT2 ;
DR   Q03K99, EX7S_STRTD ;  B9DUT8, EX7S_STRU0 ;  C1CEG9, EX7S_STRZJ ;
DR   C1CKV2, EX7S_STRZP ;  C1CR92, EX7S_STRZT ;  Q67NB3, EX7S_SYMTH ;
DR   Q2LUA0, EX7S_SYNAS ;  Q31R15, EX7S_SYNE7 ;  A0LI55, EX7S_SYNFM ;
DR   Q2JT83, EX7S_SYNJA ;  Q2JQ26, EX7S_SYNJB ;  Q5N384, EX7S_SYNP6 ;
DR   Q0AZF3, EX7S_SYNWW ;  Q9X290, EX7S_THEMA ;  B9K852, EX7S_THENN ;
DR   A5ILK1, EX7S_THEP1 ;  B0K9E2, EX7S_THEP3 ;  B0K0U9, EX7S_THEPX ;
DR   Q8RAC8, EX7S_THETN ;  B8GN64, EX7S_THISH ;  C4LAC2, EX7S_TOLAT ;
DR   B1GZX5, EX7S_UNCTG ;  A5CWU5, EX7S_VESOH ;  A5F333, EX7S_VIBC3 ;
DR   Q9KTL1, EX7S_VIBCH ;  C3LTE1, EX7S_VIBCM ;  Q5E6Y8, EX7S_VIBF1 ;
DR   B5FBG8, EX7S_VIBFM ;  A7MYC1, EX7S_VIBHB ;  Q87RT8, EX7S_VIBPA ;
DR   B7VJ99, EX7S_VIBSL ;  Q8DFA5, EX7S_VIBVU ;  Q7MN47, EX7S_VIBVY ;
DR   Q8PIY4, EX7S_XANAC ;  Q3BRG7, EX7S_XANC5 ;  Q4UWI8, EX7S_XANC8 ;
DR   B0RR28, EX7S_XANCB ;  Q8P7L2, EX7S_XANCP ;  Q2P0Q1, EX7S_XANOM ;
DR   B2SWE7, EX7S_XANOP ;  Q5GXL9, EX7S_XANOR ;  B2I7B1, EX7S_XYLF2 ;
DR   Q9PFJ7, EX7S_XYLFA ;  B0U3Y1, EX7S_XYLFM ;  Q87BE3, EX7S_XYLFT ;
DR   A1JNR4, EX7S_YERE8 ;  A7FLE2, EX7S_YERP3 ;  B2K6T9, EX7S_YERPB ;
DR   Q8ZC47, EX7S_YERPE ;  A9QZS1, EX7S_YERPG ;  Q66DV2, EX7S_YERPS ;
DR   B1JID6, EX7S_YERPY ;  Q9RME6, EX7S_ZYMMO ;
//
ID   3.1.13.1
DE   Exoribonuclease II.
AN   Ribonuclease II.
CA   Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside
CA   5'-phosphates.
CC   -!- Preference for single-stranded RNA.
CC   -!- The enzyme processes 3'-terminal extra-nucleotides of monomeric tRNA
CC       precursors, following the action of EC 3.1.26.5.
CC   -!- Similar enzymes: RNase Q, RNase BN, RNase PIII, RNase Y.
CC   -!- Formerly EC 3.1.4.20.
DR   P39112, DSS1_YEAST ;  Q96AZ6, ISG20_HUMAN;  Q9JL16, ISG20_MOUSE;
DR   Q66UW5, ISG20_PIG  ;  A3N0B9, RNB_ACTP2  ;  B3GXJ4, RNB_ACTP7  ;
DR   B0BP37, RNB_ACTPJ  ;  A6VN85, RNB_ACTSZ  ;  A0KFR1, RNB_AERHH  ;
DR   Q1LTG8, RNB_BAUCH  ;  B8D959, RNB_BUCA5  ;  P57354, RNB_BUCAI  ;
DR   Q8K9Q5, RNB_BUCAP  ;  B8D7G3, RNB_BUCAT  ;  Q89AM0, RNB_BUCBP  ;
DR   Q057Q9, RNB_BUCCC  ;  A8AG96, RNB_CITK8  ;  A7ZLA9, RNB_ECO24  ;
DR   B7UR96, RNB_ECO27  ;  B7MLW3, RNB_ECO45  ;  B7L4C3, RNB_ECO55  ;
DR   Q8X7D6, RNB_ECO57  ;  B5YZR8, RNB_ECO5E  ;  B7NVR1, RNB_ECO7I  ;
DR   B7LY47, RNB_ECO8A  ;  C4ZTY2, RNB_ECOBW  ;  B1XBN7, RNB_ECODH  ;
DR   A7ZZM6, RNB_ECOHS  ;  A1AAQ4, RNB_ECOK1  ;  Q0TI78, RNB_ECOL5  ;
DR   Q8FHT6, RNB_ECOL6  ;  B1ITG7, RNB_ECOLC  ;  P30850, RNB_ECOLI  ;
DR   B7N4A3, RNB_ECOLU  ;  B6IA03, RNB_ECOSE  ;  B1LGE7, RNB_ECOSM  ;
DR   Q1RC77, RNB_ECOUT  ;  D0Z8E6, RNB_EDWTE  ;  A4WAX5, RNB_ENT38  ;
DR   A7MMD8, RNB_ENTS8  ;  Q6D5S7, RNB_ERWCT  ;  B2VKS8, RNB_ERWT9  ;
DR   B7LRZ1, RNB_ESCF3  ;  Q7VLX8, RNB_HAEDU  ;  Q4QJL5, RNB_HAEI8  ;
DR   A5UFG3, RNB_HAEIG  ;  P44440, RNB_HAEIN  ;  B8F4C5, RNB_HAEPS  ;
DR   B5XS03, RNB_KLEP3  ;  A6T7Z4, RNB_KLEP7  ;  Q65SI5, RNB_MANSM  ;
DR   Q9CP74, RNB_PASMU  ;  C6DK05, RNB_PECCP  ;  Q7N4F5, RNB_PHOLL  ;
DR   B4EW02, RNB_PROMH  ;  A1SWZ6, RNB_PSYIN  ;  B5F571, RNB_SALA4  ;
DR   A9MQ20, RNB_SALAR  ;  Q57NV9, RNB_SALCH  ;  B5FU93, RNB_SALDC  ;
DR   B5R490, RNB_SALEP  ;  B5R9Y0, RNB_SALG2  ;  B4TJI0, RNB_SALHS  ;
DR   B4T6U4, RNB_SALNS  ;  Q5PCZ6, RNB_SALPA  ;  A9MWU8, RNB_SALPB  ;
DR   C0Q3R1, RNB_SALPC  ;  B5BIE3, RNB_SALPK  ;  B4TX11, RNB_SALSV  ;
DR   Q8Z7C9, RNB_SALTI  ;  Q8ZP54, RNB_SALTY  ;  A8GF49, RNB_SERP5  ;
DR   B2U0I4, RNB_SHIB3  ;  Q31ZY2, RNB_SHIBS  ;  Q32GP4, RNB_SHIDS  ;
DR   Q0T5B1, RNB_SHIF8  ;  P59107, RNB_SHIFL  ;  Q3Z135, RNB_SHISS  ;
DR   Q2NST6, RNB_SODGM  ;  A5F0G1, RNB_VIBC3  ;  Q9KLE1, RNB_VIBCH  ;
DR   C3LW69, RNB_VIBCM  ;  Q87IJ9, RNB_VIBPA  ;  B7VSB8, RNB_VIBSL  ;
DR   Q8D7K6, RNB_VIBVU  ;  Q7MEL4, RNB_VIBVY  ;  D3V184, RNB_XENBS  ;
DR   A1JM34, RNB_YERE8  ;  A7FI01, RNB_YERP3  ;  Q1C7L1, RNB_YERPA  ;
DR   B2K4J2, RNB_YERPB  ;  Q8ZED8, RNB_YERPE  ;  A9R8T9, RNB_YERPG  ;
DR   Q1CIZ7, RNB_YERPN  ;  A4TJ37, RNB_YERPP  ;  Q66AH3, RNB_YERPS  ;
DR   B1JKP2, RNB_YERPY  ;  Q9CH00, RNR1_LACLA ;  Q02146, RNR2_LACLA ;
DR   O67834, RNR_AQUAE  ;  O32231, RNR_BACSU  ;  P57628, RNR_BUCAI  ;
DR   Q8K917, RNR_BUCAP  ;  Q9PK00, RNR_CHLMU  ;  Q9Z848, RNR_CHLPN  ;
DR   O84402, RNR_CHLTR  ;  P21499, RNR_ECOLI  ;  P44907, RNR_HAEIN  ;
DR   Q9ZJX9, RNR_HELPJ  ;  P56123, RNR_HELPY  ;  P47350, RNR_MYCGE  ;
DR   P75529, RNR_MYCPN  ;  Q98QL0, RNR_MYCPU  ;  P30851, RNR_SHIFL  ;
DR   Q9WZI1, RNR_THEMA  ;  P54084, RNR_THIFE  ;  Q9PR88, RNR_UREPA  ;
DR   Q9KNY1, RNR_VIBCH  ;  P40611, RNR_VIBPA  ;  Q1MTN7, RPM1_SCHPO ;
//
ID   3.1.13.2
DE   Exoribonuclease H.
CA   3'-end directed exonucleolytic cleavage of viral RNA-DNA hybrid.
CC   -!- This is a secondary reaction to the RNA 5'-end directed cleavage
CC       13-19 nucleotides from the RNA end performed by EC 3.1.26.13.
DR   P19560, POL_BIV29  ;  P33459, POL_CAEVC  ;  P11204, POL_EIAV9  ;
DR   P32542, POL_EIAVC  ;  P03371, POL_EIAVY  ;  P16088, POL_FIVPE  ;
DR   P19028, POL_FIVSD  ;  P31822, POL_FIVT2  ;  O93215, POL_HV190  ;
DR   O12158, POL_HV192  ;  O89290, POL_HV193  ;  Q9QBY3, POL_HV196  ;
DR   Q9QBZ9, POL_HV197  ;  O41798, POL_HV19N  ;  P03369, POL_HV1A2  ;
DR   Q77373, POL_HV1AN  ;  P03366, POL_HV1B1  ;  P04587, POL_HV1B5  ;
DR   Q73368, POL_HV1B9  ;  P03367, POL_HV1BR  ;  P04589, POL_HV1EL  ;
DR   Q75002, POL_HV1ET  ;  P04585, POL_HV1H2  ;  P20875, POL_HV1JR  ;
DR   P0C6F2, POL_HV1LW  ;  Q9QBZ1, POL_HV1M2  ;  P04588, POL_HV1MA  ;
DR   P05961, POL_HV1MN  ;  Q9QBZ5, POL_HV1MP  ;  Q79666, POL_HV1MV  ;
DR   P12497, POL_HV1N5  ;  P18802, POL_HV1ND  ;  P20892, POL_HV1OY  ;
DR   P05959, POL_HV1RH  ;  Q9WC54, POL_HV1S2  ;  Q9WC63, POL_HV1S9  ;
DR   O89940, POL_HV1SE  ;  P24740, POL_HV1U4  ;  Q9Q720, POL_HV1V9  ;
DR   Q9QSR3, POL_HV1VI  ;  P35963, POL_HV1Y2  ;  Q9IDV9, POL_HV1YB  ;
DR   O91080, POL_HV1YF  ;  P12499, POL_HV1Z2  ;  P18096, POL_HV2BE  ;
DR   P24107, POL_HV2CA  ;  P17757, POL_HV2D1  ;  P15833, POL_HV2D2  ;
DR   Q89928, POL_HV2EH  ;  P18042, POL_HV2G1  ;  Q74120, POL_HV2KR  ;
DR   P05962, POL_HV2NZ  ;  P04584, POL_HV2RO  ;  P12451, POL_HV2SB  ;
DR   P20876, POL_HV2ST  ;  Q76634, POL_HV2UC  ;  Q82851, POL_JEMBR  ;
DR   P16901, POL_OMVVS  ;  P17283, POL_SIVCZ  ;  Q1A249, POL_SIVEK  ;
DR   Q02836, POL_SIVG1  ;  P22382, POL_SIVGB  ;  P05896, POL_SIVM1  ;
DR   Q1A267, POL_SIVMB  ;  P05897, POL_SIVMK  ;  P12502, POL_SIVS4  ;
DR   P19505, POL_SIVSP  ;  Q8AII1, POL_SIVTN  ;  P27973, POL_SIVV1  ;
DR   P12500, POL_SIVV2  ;  P12501, POL_SIVV3  ;  P27980, POL_SIVVG  ;
DR   P05895, POL_SIVVT  ;  P03370, POL_VILV   ;  P23426, POL_VILV1  ;
DR   P23427, POL_VILV2  ;  P35956, POL_VILVK  ;
//
ID   3.1.13.3
DE   Oligonucleotidase.
CA   Exonucleolytic cleavage of oligonucleotides to yield nucleoside
CA   5'-phosphates.
CC   -!- Also hydrolyzes NAD(+) to NMN and AMP.
CC   -!- Formerly EC 3.1.4.19.
//
ID   3.1.13.4
DE   Poly(A)-specific ribonuclease.
CA   Exonucleolytic cleavage of poly(A) to 5'-AMP.
CC   -!- Cleaves poly(A) in either the single- or double-stranded form.
DR   Q9SHJ0, CAF1A_ARATH;  Q9S9P2, CAF1B_ARATH;  Q9SFX6, CAF1C_ARATH;
DR   Q9C6M9, CAF1D_ARATH;  O64773, CAF1E_ARATH;  Q9SAI2, CAF1F_ARATH;
DR   Q9SKZ2, CAF1G_ARATH;  Q9LXM4, CAF1H_ARATH;  Q9LXM2, CAF1I_ARATH;
DR   Q9LEU4, CAF1J_ARATH;  Q9FMS6, CAF1K_ARATH;  O74856, CAF1_SCHPO ;
DR   Q8W0Z9, CCR4A_ARATH;  Q9M2F8, CCR4B_ARATH;  Q9LS39, CCR4C_ARATH;
DR   A8MS41, CCR4D_ARATH;  Q0WKY2, CCR4E_ARATH;  Q8VYU4, CCR4F_ARATH;
DR   Q75BI3, CCR4_ASHGO ;  A1CIJ6, CCR4_ASPCL ;  Q4WQG5, CCR4_ASPFU ;
DR   A2Q9L0, CCR4_ASPNC ;  Q2UUI3, CCR4_ASPOR ;  Q0CT27, CCR4_ASPTN ;
DR   Q5A761, CCR4_CANAL ;  Q6FRT2, CCR4_CANGA ;  Q1EA11, CCR4_COCIM ;
DR   P0CP23, CCR4_CRYNB ;  P0CP22, CCR4_CRYNJ ;  Q6BMM5, CCR4_DEBHA ;
DR   Q5B778, CCR4_EMENI ;  Q8SU52, CCR4_ENCCU ;  B7XK66, CCR4_ENTBH ;
DR   Q6CJU4, CCR4_KLULA ;  A1CW67, CCR4_NEOFI ;  Q9C2R2, CCR4_NEUCR ;
DR   C4V7I7, CCR4_NOSCE ;  Q0U7W4, CCR4_PHANO ;  O74874, CCR4_SCHPO ;
DR   Q4P9T3, CCR4_USTMA ;  Q6CEJ6, CCR4_YARLI ;  P31384, CCR4_YEAST ;
DR   Q754X1, PAN2_ASHGO ;  A1CEK7, PAN2_ASPCL ;  Q4WHP6, PAN2_ASPFU ;
DR   A2QW83, PAN2_ASPNC ;  Q2ULU6, PAN2_ASPOR ;  Q0CJU7, PAN2_ASPTN ;
DR   Q5APK0, PAN2_CANAL ;  Q6FS70, PAN2_CANGA ;  Q2GSV2, PAN2_CHAGB ;
DR   Q5F450, PAN2_CHICK ;  Q1E873, PAN2_COCIM ;  P0CQ09, PAN2_CRYNB ;
DR   P0CQ08, PAN2_CRYNJ ;  Q6BZ78, PAN2_DEBHA ;  Q5BBL5, PAN2_EMENI ;
DR   Q504Q3, PAN2_HUMAN ;  Q6CMN5, PAN2_KLULA ;  A5E1W0, PAN2_LODEL ;
DR   A4RF51, PAN2_MAGO7 ;  Q8BGF7, PAN2_MOUSE ;  A1DFN6, PAN2_NEOFI ;
DR   P0C581, PAN2_NEUCR ;  Q0UPL5, PAN2_PHANO ;  A5DAD0, PAN2_PICGU ;
DR   A3LRV8, PAN2_PICST ;  Q6IE70, PAN2_RAT   ;  Q09798, PAN2_SCHPO ;
DR   Q6C462, PAN2_YARLI ;  P53010, PAN2_YEAST ;  Q8W4C3, PARNL_ARATH;
DR   Q9LG26, PARN_ARATH ;  P69341, PARN_BOVIN ;  Q7ZU92, PARN_DANRE ;
DR   O95453, PARN_HUMAN ;  Q8VDG3, PARN_MOUSE ;  Q5RC51, PARN_PONAB ;
DR   Q90ZA1, PARN_XENLA ;  P39008, POP2_YEAST ;
//
ID   3.1.13.5
DE   Ribonuclease D.
AN   RNase D.
CA   Exonucleolytic cleavage that removes extra residues from the 3'-terminus
CA   of tRNA to produce 5'-mononucleotides.
CF   Cobalt or manganese or magnesium.
CC   -!- Alteration of the 3'-terminal base has no effect on the rate of
CC       hydrolysis whereas modification of the 3'-terminal sugar has a major
CC       effect.
CC   -!- tRNA terminating with a 3'-phosphate is completely inactive.
CC   -!- This enzyme can convert a tRNA precursor into a mature tRNA.
DR   A5G127, RND_ACICJ  ;  Q6G329, RND_BARHE  ;  C9XUE4, RND_CROTZ  ;
DR   Q6AJF4, RND_DESPS  ;  C6C608, RND_DICDC  ;  P09155, RND_ECOLI  ;
DR   A9H9B7, RND_GLUDA  ;  Q0BVP4, RND_GRABC  ;  P44442, RND_HAEIN  ;
DR   Q28RA7, RND_JANSC  ;  B8EN54, RND_METSB  ;  Q1QLI8, RND_NITHX  ;
DR   A7HYE5, RND_PARL1  ;  A6V8R6, RND_PSEA7  ;  A1SVE6, RND_PSYIN  ;
DR   A8GFH0, RND_SERP5  ;  A0KXU5, RND_SHESA  ;  D4Z694, RND_SPHJU  ;
DR   Q5GZ75, RND_XANOR  ;  Q5NPM2, RND_ZYMMO  ;
//
ID   3.1.14.1
DE   Yeast ribonuclease.
CA   Exonucleolytic cleavage to nucleoside 3'-phosphates.
CC   -!- Similar enzyme: RNase U4.
//
ID   3.1.15.1
DE   Venom exonuclease.
AN   Venom phosphodiesterase.
CA   Exonucleolytic cleavage in the 3'- to 5'- direction to yield nucleoside
CA   5'-phosphates.
CC   -!- Preference for single-stranded substrate.
CC   -!- Similar enzymes: hog kidney phosphodiesterase, Lactobacillus
CC       exonuclease.
//
ID   3.1.16.1
DE   Spleen exonuclease.
AN   3'-exonuclease.
AN   Spleen phosphodiesterase.
CA   Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside
CA   3'-phosphates.
CC   -!- Preference for single-stranded substrate.
CC   -!- Similar enzymes: Lactobacillus acidophilus nuclease, Bacillus
CC       subtilis nuclease, salmon testis nuclease.
CC   -!- Formerly EC 3.1.4.18.
//
ID   3.1.21.1
DE   Deoxyribonuclease I.
AN   DNase.
AN   Pancreatic DNase.
AN   Thymonuclease.
CA   Endonucleolytic cleavage to 5'-phosphodinucleotide and
CA   5'-phosphooligonucleotide end-products.
CC   -!- Preference for double-stranded DNA.
CC   -!- Similar enzymes: streptococcal DNase (streptodornase),
CC       T4 endonuclease II, T7 endonuclease II, Escherichia coli endonuclease
CC       I, 'nicking' nuclease of calf thymus, colicin E2 and E3.
CC   -!- Formerly EC 3.1.4.5.
PR   PROSITE; PDOC00711;
DR   P00639, DNAS1_BOVIN;  Q767J3, DNAS1_CANFA;  Q9YGI5, DNAS1_CHICK;
DR   Q4AEE3, DNAS1_HORSE;  P24855, DNAS1_HUMAN;  P49183, DNAS1_MOUSE;
DR   O42446, DNAS1_OREMO;  P11936, DNAS1_PIG  ;  O18998, DNAS1_RABIT;
DR   P21704, DNAS1_RAT  ;  P11937, DNAS1_SHEEP;  P26295, DRN1_STREQ ;
DR   P57487, END1_BUCAI ;  Q89AD7, END1_BUCBP ;  P25736, END1_ECOLI ;
DR   P07059, END2_BPT4  ;
//
ID   3.1.21.2
DE   Deoxyribonuclease IV (phage-T(4)-induced).
AN   Deoxyribonuclease IV (phage T4-induced).
AN   Endodeoxyribonuclease IV (phage T(4)-induced).
AN   Endodeoxyribonuclease IV (phage T4-induced).
AN   Endonuclease IV.
CA   Endonucleolytic cleavage to 5'-phosphooligonucleotide end-products.
CC   -!- Preference for single-stranded DNA.
CC   -!- Similar enzymes: DNase V (mammalian), Aspergillus sojae DNase,
CC       Bacillus subtilis endonuclease, T4 endonuclease III, T7 endonuclease
CC       I, Aspergillus DNase K2, vaccinia virus DNase VI, Saccharomyces
CC       cerevisiae DNase, Chlorella DNase.
CC   -!- Formerly EC 3.1.4.30.
PR   PROSITE; PDOC00599;
DR   A9NFH1, END4_ACHLI ;  A3MZ76, END4_ACTP2 ;  B3H0M0, END4_ACTP7 ;
DR   B0BTA9, END4_ACTPJ ;  A0KK26, END4_AERHH ;  A4SMZ0, END4_AERS4 ;
DR   B2UQE3, END4_AKKM8 ;  A8ML82, END4_ALKOO ;  B7GH81, END4_ANOFW ;
DR   O67551, END4_AQUAE ;  A8EWW1, END4_ARCB4 ;  Q2NJF9, END4_AYWBP ;
DR   A7Z6S8, END4_BACA2 ;  C3P8J1, END4_BACAA ;  C3LKW3, END4_BACAC ;
DR   A0RIQ8, END4_BACAH ;  Q81LV1, END4_BACAN ;  B7JN09, END4_BACC0 ;
DR   B7IYD6, END4_BACC2 ;  C1ES07, END4_BACC3 ;  B7HCQ9, END4_BACC4 ;
DR   B7HPI4, END4_BACC7 ;  A7GSY1, END4_BACCN ;  B9IY53, END4_BACCQ ;
DR   Q818H3, END4_BACCR ;  Q634Q3, END4_BACCZ ;  Q5LG28, END4_BACFN ;
DR   Q64WY5, END4_BACFR ;  Q9KD33, END4_BACHD ;  Q6HDN3, END4_BACHK ;
DR   Q65HA0, END4_BACLD ;  Q5WHC2, END4_BACSK ;  P54476, END4_BACSU ;
DR   Q89YT0, END4_BACTN ;  A6L330, END4_BACV8 ;  A9VHR4, END4_BACWK ;
DR   B3DS13, END4_BIFLD ;  Q8G689, END4_BIFLO ;  B7GRN1, END4_BIFLS ;
DR   B8D8T8, END4_BUCA5 ;  P57237, END4_BUCAI ;  P59058, END4_BUCAP ;
DR   B8D742, END4_BUCAT ;  P59496, END4_BUCBP ;  A8Z6D9, END4_CAMC1 ;
DR   A7GW36, END4_CAMC5 ;  A0RRG4, END4_CAMFF ;  A7I010, END4_CAMHC ;
DR   Q3ABA7, END4_CARHZ ;  A0RYW7, END4_CENSY ;  A9WII8, END4_CHLAA ;
DR   Q5L798, END4_CHLAB ;  B8G418, END4_CHLAD ;  Q3AT74, END4_CHLCH ;
DR   Q824X6, END4_CHLCV ;  B3EEJ7, END4_CHLL2 ;  Q9PJB8, END4_CHLMU ;
DR   B3QQA9, END4_CHLP8 ;  B3ELV8, END4_CHLPB ;  Q9Z7H3, END4_CHLPN ;
DR   B9LAM9, END4_CHLSY ;  B0B8K0, END4_CHLT2 ;  Q3KL70, END4_CHLTA ;
DR   B0BA79, END4_CHLTB ;  Q8KFL0, END4_CHLTE ;  O84630, END4_CHLTR ;
DR   A8AE66, END4_CITK8 ;  A6LQV9, END4_CLOB8 ;  B2V158, END4_CLOBA ;
DR   B2TL64, END4_CLOBB ;  Q189A4, END4_CLOD6 ;  A9KNS9, END4_CLOPH ;
DR   C0QMG1, END4_DESAH ;  Q30YP7, END4_DESDG ;  A8ZSE7, END4_DESOH ;
DR   Q6ASE4, END4_DESPS ;  Q72CQ9, END4_DESVH ;  A1VEI5, END4_DESVV ;
DR   Q966U0, END4_DICDI ;  A7ZNY3, END4_ECO24 ;  B7UFH5, END4_ECO27 ;
DR   B7MF74, END4_ECO45 ;  B7LAI2, END4_ECO55 ;  P0A6C2, END4_ECO57 ;
DR   B5YWV0, END4_ECO5E ;  B7NMX3, END4_ECO7I ;  B7MX24, END4_ECO81 ;
DR   B7M507, END4_ECO8A ;  C4ZU09, END4_ECOBW ;  B1X857, END4_ECODH ;
DR   A8A222, END4_ECOHS ;  A1AD18, END4_ECOK1 ;  Q0TFT1, END4_ECOL5 ;
DR   Q8FFU0, END4_ECOL6 ;  B1IYB0, END4_ECOLC ;  P0A6C1, END4_ECOLI ;
DR   B7N5C2, END4_ECOLU ;  B6I8L0, END4_ECOSE ;  B1LKQ6, END4_ECOSM ;
DR   Q1R9R2, END4_ECOUT ;  C5BCN2, END4_EDWI9 ;  A4WCJ5, END4_ENT38 ;
DR   Q834D0, END4_ENTFA ;  A7MLL2, END4_ENTS8 ;  Q6D3L8, END4_ERWCT ;
DR   B2VIH1, END4_ERWT9 ;  B7LVB9, END4_ESCF3 ;  B1YL88, END4_EXIS2 ;
DR   B0S196, END4_FINM2 ;  B5EAS8, END4_GEOBB ;  Q5KX27, END4_GEOKA ;
DR   B3E325, END4_GEOLS ;  B9M4N1, END4_GEOSF ;  Q74FS7, END4_GEOSL ;
DR   C6DYE3, END4_GEOSM ;  C5D4R0, END4_GEOSW ;  A4IR02, END4_GEOTN ;
DR   Q7VMC4, END4_HAEDU ;  B8F7D1, END4_HAEPS ;  A1WXM0, END4_HALHL ;
DR   Q5V0S8, END4_HALMA ;  B8CW79, END4_HALOH ;  B0R2U6, END4_HALS3 ;
DR   Q9HSK7, END4_HALSA ;  Q18KA6, END4_HALWD ;  B0TD39, END4_HELMI ;
DR   A9B5N7, END4_HERA2 ;  B5XP51, END4_KLEP3 ;  A6TBP4, END4_KLEP7 ;
DR   Q88VR2, END4_LACPL ;  Q38XB2, END4_LACSS ;  Q92BR0, END4_LISIN ;
DR   C1KV96, END4_LISMC ;  Q71ZM1, END4_LISMF ;  Q8Y756, END4_LISMO ;
DR   A0AIQ1, END4_LISW6 ;  B1HTF6, END4_LYSSC ;  A0L901, END4_MAGSM ;
DR   Q6F1D3, END4_MESFL ;  A2SPZ6, END4_METLZ ;  A3CT71, END4_METMJ ;
DR   B8GKX5, END4_METPE ;  Q2NFM3, END4_METST ;  Q5UPY4, END4_MIMIV ;
DR   Q2RJF1, END4_MOOTA ;  B3PMH1, END4_MYCA5 ;  A5IYT8, END4_MYCAP ;
DR   P63536, END4_MYCBO ;  A1KGF0, END4_MYCBP ;  C1AL03, END4_MYCBT ;
DR   Q2ST57, END4_MYCCT ;  Q7NBA9, END4_MYCGA ;  P47477, END4_MYCGE ;
DR   Q601Y6, END4_MYCH2 ;  Q4A8V0, END4_MYCH7 ;  Q4AAX4, END4_MYCHJ ;
DR   B8ZSC5, END4_MYCLB ;  P30770, END4_MYCLE ;  B2HSJ8, END4_MYCMM ;
DR   Q6KH96, END4_MYCMO ;  Q6MUC7, END4_MYCMS ;  Q8EWT2, END4_MYCPE ;
DR   P75457, END4_MYCPN ;  Q98PU8, END4_MYCPU ;  Q4A6S5, END4_MYCS5 ;
DR   A5U056, END4_MYCTA ;  P63535, END4_MYCTU ;  A0PM27, END4_MYCUA ;
DR   Q3IMK8, END4_NATPD ;  B2A499, END4_NATTJ ;  B9L9K0, END4_NAUPA ;
DR   A9A555, END4_NITMS ;  A6Q1P1, END4_NITSB ;  Q8EPZ2, END4_OCEIH ;
DR   Q6YQC1, END4_ONYPE ;  A6LB99, END4_PARD8 ;  Q6MED0, END4_PARUW ;
DR   C6DEL1, END4_PECCP ;  Q03F56, END4_PEDPA ;  Q3B5R5, END4_PELLD ;
DR   B4SE58, END4_PELPB ;  C0QRI1, END4_PERMH ;  A9BJ15, END4_PETMO ;
DR   Q7N364, END4_PHOLL ;  Q6LUP5, END4_PHOPR ;  B4S3I3, END4_PROA2 ;
DR   B4ETA5, END4_PROMH ;  A4SDE2, END4_PROVI ;  B5EYQ5, END4_SALA4 ;
DR   A9MK49, END4_SALAR ;  Q57MD6, END4_SALCH ;  B5FNK8, END4_SALDC ;
DR   B5R173, END4_SALEP ;  B5RC42, END4_SALG2 ;  B4TAM6, END4_SALHS ;
DR   B4SY37, END4_SALNS ;  Q5PE50, END4_SALPA ;  A9N6I5, END4_SALPB ;
DR   C0Q0T7, END4_SALPC ;  B5BE34, END4_SALPK ;  B4TNR0, END4_SALSV ;
DR   Q8Z593, END4_SALTI ;  Q8ZNK6, END4_SALTY ;  A8GGT5, END4_SERP5 ;
DR   B2TVT4, END4_SHIB3 ;  Q31YW6, END4_SHIBS ;  Q32EQ7, END4_SHIDS ;
DR   Q0T2W5, END4_SHIF8 ;  Q83QW6, END4_SHIFL ;  Q3Z047, END4_SHISS ;
DR   Q01TU5, END4_SOLUE ;  A7X2V2, END4_STAA1 ;  A6U229, END4_STAA2 ;
DR   Q2FGG6, END4_STAA3 ;  Q2FY16, END4_STAA8 ;  A5IT85, END4_STAA9 ;
DR   Q2YT22, END4_STAAB ;  Q5HFK3, END4_STAAC ;  A6QHA0, END4_STAAE ;
DR   P63537, END4_STAAM ;  P63538, END4_STAAN ;  Q6GGE2, END4_STAAR ;
DR   Q6G909, END4_STAAS ;  A8Z497, END4_STAAT ;  P63539, END4_STAAW ;
DR   B9DNM8, END4_STACT ;  Q5HNZ1, END4_STAEQ ;  Q8CP25, END4_STAES ;
DR   Q4L6Q7, END4_STAHJ ;  Q49Y00, END4_STAS1 ;  Q82AG6, END4_STRAW ;
DR   Q9S2N2, END4_STRCO ;  Q30PH2, END4_SULDN ;  A6QCI0, END4_SULNB ;
DR   B2V7A4, END4_SULSY ;  Q67S99, END4_SYMTH ;  B7IDS7, END4_THEAB ;
DR   Q9HJS3, END4_THEAC ;  A6LMU8, END4_THEM4 ;  Q9WYJ7, END4_THEMA ;
DR   O86954, END4_THENE ;  B9KBS2, END4_THENN ;  A5IK54, END4_THEP1 ;
DR   B1L9C6, END4_THESQ ;  Q72KH8, END4_THET2 ;  Q97A09, END4_THEVO ;
DR   C4LD49, END4_TOLAT ;  Q9PQI5, END4_UREPA ;  B5ZBB4, END4_UREU1 ;
DR   A5F5R6, END4_VIBC3 ;  Q9KPK7, END4_VIBCH ;  C3LQD2, END4_VIBCM ;
DR   A7MS84, END4_VIBHB ;  Q87SC6, END4_VIBPA ;  Q8DEP6, END4_VIBVU ;
DR   Q7MNR1, END4_VIBVY ;  Q7M8B4, END4_WOLSU ;  A1JLX8, END4_YERE8 ;
DR   P42691, END4_YEREN ;  A7FK62, END4_YERP3 ;  Q1C982, END4_YERPA ;
DR   B2K9J1, END4_YERPB ;  Q8ZGJ1, END4_YERPE ;  A9R4S1, END4_YERPG ;
DR   Q1CG79, END4_YERPN ;  A4TNA4, END4_YERPP ;  Q66CR5, END4_YERPS ;
DR   B1JRM5, END4_YERPY ;  P20314, ENRN_BPT3  ;  P00641, ENRN_BPT7  ;
//
ID   3.1.21.3
DE   Type I site-specific deoxyribonuclease.
AN   Type I restriction enzyme.
CA   Endonucleolytic cleavage of DNA to give random double-stranded fragments
CA   with terminal 5'-phosphates; ATP is simultaneously hydrolyzed.
CC   -!- Large group of enzymes that have an absolute requirement for ATP (or
CC       dATP) and S-adenosyl-L-methionine.
CC   -!- They recognize specific short DNA sequences and cleave at sites
CC       remote from the recognition sequence.
CC   -!- Multifunctional proteins which also catalyze the reactions of
CC       EC 2.1.1.72 and EC 2.1.1.73, with similar site specificity.
CC   -!- Formerly EC 3.1.24.1 and EC 3.1.24.2.
CC   -!- See the REBASE database for a complete list of these enzymes:
CC       http://rebase.neb.com/rebase/
DR   Q5HJH8, HSDR_STAAC ;  Q99X26, HSDR_STAAM ;  Q7A801, HSDR_STAAN ;
DR   Q6GKB1, HSDR_STAAR ;  Q6GCT1, HSDR_STAAS ;  Q8NYL9, HSDR_STAAW ;
DR   Q5HK76, HSDR_STAEQ ;  Q4A127, HSDR_STAS1 ;  P10486, T1R1_ECOLX ;
DR   Q07736, T1RA_ECOLX ;  Q47281, T1RE_ECOLX ;  O05052, T1RH_HAEIN ;
DR   Q60295, T1RH_METJA ;  P08956, T1RK_ECOLI ;  P17224, T1RP_ECOLX ;
DR   P75431, T1RX_MYCPN ;  P75433, T1RY_MYCPN ;
//
ID   3.1.21.4
DE   Type II site-specific deoxyribonuclease.
AN   Type II restriction enzyme.
CA   Endonucleolytic cleavage of DNA to give specific double-stranded
CA   fragments with terminal 5'-phosphates.
CF   Magnesium.
CC   -!- Large group of enzymes which recognize specific short DNA sequences
CC       and cleave either within, or at a short specific distance from,
CC       the recognition site.
CC   -!- See the REBASE database for a complete list of these enzymes:
CC       http://rebase.neb.com/rebase/
DR   P25239, T257_ECOLX ;  O52703, T2A1_ACEPA ;  P24546, T2A1_ACICA ;
DR   P0A458, T2A1_ANAVA ;  P26919, T2A1_AZOBR ;  P0A457, T2A1_NOSS1 ;
DR   Q9KHV6, T2A1_RUEGE ;  O68557, T2B1_BACSU ;  P70985, T2B1_GEOSE ;
DR   P25257, T2B1_HERAU ;  Q50973, T2B1_NEIGO ;  Q45488, T2B2_BACSU ;
DR   Q50975, T2B5_NEIGO ;  P43419, T2B6_BACSF ;  P23940, T2BA_BACAM ;
DR   P19887, T2BA_BACAR ;  P33562, T2BB_BACSU ;  P25217, T2BF_BACSU ;
DR   Q9LAI1, T2BLA_BACSQ;  Q9LAI0, T2BLB_BACSQ;  P06529, T2BR_BACSU ;
DR   Q04852, T2C1_CITFR ;  P42827, T2C1_COREQ ;  P25258, T2C1_HERAU ;
DR   P52283, T2C1_PBCVI ;  P17743, T2C2_HAEIF ;  P25259, T2C2_HERAU ;
DR   P31117, T2C2_PBCV1 ;  Q60132, T2C9_CITFR ;  P56200, T2CX_CITFR ;
DR   P05301, T2D1_DESNO ;  P24599, T2D1_HERAU ;  Q9RLM3, T2D1_NEIMC ;
DR   P0A459, T2D1_STRPN ;  P0A460, T2D1_STRR6 ;  P44413, T2D2_HAEIN ;
DR   P09357, T2D2_STRPN ;  P43870, T2D3_HAEIN ;  P44999, T2D5_HAEIN ;
DR   P00642, T2E1_ECOLX ;  P25260, T2E1_HERAU ;  P14633, T2E2_ECOLX ;
DR   P04390, T2E5_ECOLX ;  P50194, T2E7_ECOLX ;  P50195, T2E8_ECOLX ;
DR   P20588, T2F1_HAEIF ;  P14870, T2F1_PLAOK ;  Q50976, T2F7_NEIGO ;
DR   P43418, T2G1_HAEGA ;  P25261, T2G1_HERAU ;  P29537, T2H1_HAEPA ;
DR   P50191, T2H1_HAEPH ;  O30869, T2H2_HAEAE ;  P36433, T2H2_HAEPA ;
DR   P00643, T2H2_HAEPH ;  O68584, T2H3_HAEAE ;  P25237, T2K1_KLEPN ;
DR   P50177, T2L2_LACLC ;  Q58391, T2M1_METJA ;  P50189, T2M1_MICAM ;
DR   P34719, T2M1_MORBO ;  P11405, T2M1_MORSP ;  Q58844, T2M2_METJA ;
DR   P23191, T2M2_MORBO ;  Q58017, T2M3_METJA ;  Q58723, T2M4_METJA ;
DR   P31032, T2M4_NEIGO ;  Q58895, T2M5_METJA ;  P81326, T2M6_METJA ;
DR   P29565, T2MT_METTF ;  P43642, T2MU_MYCSP ;  O59646, T2MW_METWO ;
DR   P29566, T2MZ_METTF ;  P50187, T2N1_NOCAE ;  Q51083, T2N3_NEILA ;
DR   P50183, T2N4_NEILA ;  P35677, T2N5_NOSS7 ;  P31031, T2P1_PROHU ;
DR   P24617, T2P2_NEIGO ;  P23657, T2P2_PROHU ;  P05104, T2P7_PSEAE ;
DR   P00640, T2PS_PROST ;  P21763, T2R1_RHOSH ;  O34104, T2S1_LACLC ;
DR   P09796, T2S1_SALIN ;  O31074, T2S1_STRAH ;  Q53608, T2S1_STRAL ;
DR   O52691, T2S1_STRCS ;  O52512, T2S1_STRFI ;  P29346, T2S1_STRSA ;
DR   P34880, T2S2_SHISO ;  P16667, T2S3_STAAU ;  P23736, T2S9_STAAU ;
DR   P14229, T2SM_SERMA ;  P29748, T2T8_THET8 ;  P14386, T2TA_THEAQ ;
DR   P43421, T2V1_GEOSE ;  P30773, T2X1_XANCC ;  P96189, T2X1_XANCR ;
DR   Q9KVZ7, T2X1_XANVA ;  O35025, YDIR_BACSU ;  O34885, YDIS_BACSU ;
DR   O34303, YDJA_BACSU ;
//
ID   3.1.21.5
DE   Type III site-specific deoxyribonuclease.
AN   Type III restriction enzyme.
CA   Endonucleolytic cleavage of DNA to give specific double-stranded
CA   fragments with terminal 5'-phosphates.
CC   -!- Has an absolute requirement for ATP, but does not hydrolyze it;
CC       S-adenosyl-L-methionine stimulates the reaction, but is not
CC       absolutely required.
CC   -!- Recognize specific short DNA sequences and cleave a short distance
CC       away from the recognition sequence.
CC   -!- Exist as complexes with enzymes of similar specificity listed under
CC       EC 2.1.1.72 or EC 2.1.1.73.
CC   -!- Formerly EC 3.1.24.3 and EC 3.1.24.4.
CC   -!- See the REBASE database for a complete list of these enzymes:
CC       http://rebase.neb.com/rebase/
DR   P25241, T3RE_BACC1 ;  P08764, T3RE_BPP1  ;  P40815, T3RE_SALTY ;
DR   P44105, T3RH_HAEIN ;
//
ID   3.1.21.6
DE   CC-preferring endodeoxyribonuclease.
AN   5'-CC-3'-preferring endodeoxyribonuclease.
AN   Streptomyces glaucescens exocytoplasmic endodeoxyribonuclease.
AN   Streptomyces glaucescens exocytoplasmic endonuclease.
CA   Endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products,
CA   with a preference for cleavage within the sequence CC.
CF   Magnesium.
CC   -!- Prefers CC sites in double-stranded circular and linear DNA.
CC   -!- Greater affinity for double-stranded than single-stranded DNA.
CC   -!- Produces nicks, generating double-stranded fragments with 5'- and/or
CC       3'-protruding single-stranded tails.
//
ID   3.1.21.7
DE   Deoxyribonuclease V.
AN   DNase V.
AN   Endonuclease V.
AN   Escherichia coli endodeoxyribonuclease V.
CA   Endonucleolytic cleavage at apurinic or apyrimidinic sites to products
CA   with a 5'-phosphate.
CC   -!- Previously classified erroneously as EC 3.1.22.3.
DR   Q9YES5, NFI_AERPE  ;  Q0A5M1, NFI_ALHEH  ;  Q3MEZ3, NFI_ANAVT  ;
DR   O66824, NFI_AQUAE  ;  O30108, NFI_ARCFU  ;  C1DQ77, NFI_AZOVD  ;
DR   A7Z9I5, NFI_BACA2  ;  Q6HGE0, NFI_BACHK  ;  P96724, NFI_BACSU  ;
DR   A8AKS5, NFI_CITK8  ;  Q97M37, NFI_CLOAB  ;  B7K379, NFI_CYAP8  ;
DR   A5FRP8, NFI_DEHSB  ;  Q3ZWY7, NFI_DEHSC  ;  B8D509, NFI_DESK1  ;
DR   B5YD80, NFI_DICT6  ;  B8DZX0, NFI_DICTD  ;  A7ZUL4, NFI_ECO24  ;
DR   B7UPF3, NFI_ECO27  ;  B7MIY4, NFI_ECO45  ;  B7LA92, NFI_ECO55  ;
DR   P68741, NFI_ECO57  ;  B5Z094, NFI_ECO5E  ;  B7NRT1, NFI_ECO7I  ;
DR   B7N2K0, NFI_ECO81  ;  B7M7Q7, NFI_ECO8A  ;  C5A0T9, NFI_ECOBW  ;
DR   B1XC01, NFI_ECODH  ;  A8A798, NFI_ECOHS  ;  A1AIG9, NFI_ECOK1  ;
DR   Q0TA67, NFI_ECOL5  ;  P68740, NFI_ECOL6  ;  B1IUP9, NFI_ECOLC  ;
DR   P68739, NFI_ECOLI  ;  B7NFT9, NFI_ECOLU  ;  B6I5K9, NFI_ECOSE  ;
DR   B1LNV0, NFI_ECOSM  ;  Q1R5W4, NFI_ECOUT  ;  A4W5C1, NFI_ENT38  ;
DR   A7MJ90, NFI_ENTS8  ;  B2VG82, NFI_ERWT9  ;  B7LUK4, NFI_ESCF3  ;
DR   A5GD74, NFI_GEOUR  ;  Q7NDJ2, NFI_GLOVI  ;  Q5V474, NFI_HALMA  ;
DR   Q9HS81, NFI_HALSA  ;  A8A9B8, NFI_IGNH4  ;  B5XYE0, NFI_KLEP3  ;
DR   A6TGQ5, NFI_KLEP7  ;  C5CGG9, NFI_KOSOT  ;  Q60CT7, NFI_METCA  ;
DR   Q8X260, NFI_METKA  ;  A0B8N3, NFI_METTP  ;  Q1DC68, NFI_MYXXD  ;
DR   Q74NK2, NFI_NANEQ  ;  Q3IT64, NFI_NATPD  ;  Q5YQW3, NFI_NOCFA  ;
DR   B2IWL4, NFI_NOSP7  ;  Q8YPV5, NFI_NOSS1  ;  Q6MDK2, NFI_PARUW  ;
DR   C6DHT0, NFI_PECCP  ;  A9BHL9, NFI_PETMO  ;  Q7N959, NFI_PHOLL  ;
DR   Q6KZ38, NFI_PICTO  ;  B4EYT7, NFI_PROMH  ;  Q9UYX5, NFI_PYRAB  ;
DR   Q8ZYP2, NFI_PYRAE  ;  Q8U263, NFI_PYRFU  ;  O58394, NFI_PYRHO  ;
DR   Q5JI47, NFI_PYRKO  ;  B6IUZ1, NFI_RHOCS  ;  A7NSC5, NFI_ROSCS  ;
DR   A5UWX7, NFI_ROSS1  ;  B5F1I1, NFI_SALA4  ;  A9MHD1, NFI_SALAR  ;
DR   Q57H57, NFI_SALCH  ;  B5FQL3, NFI_SALDC  ;  B5QYF3, NFI_SALEP  ;
DR   B5RFI6, NFI_SALG2  ;  B4TCT7, NFI_SALHS  ;  B4T100, NFI_SALNS  ;
DR   Q5PKA2, NFI_SALPA  ;  A9N0L0, NFI_SALPB  ;  C0Q2T0, NFI_SALPC  ;
DR   B5BJR7, NFI_SALPK  ;  B4TQK8, NFI_SALSV  ;  P68737, NFI_SALTI  ;
DR   P68738, NFI_SALTY  ;  A8G8F8, NFI_SERP5  ;  B2TWI5, NFI_SHIB3  ;
DR   Q32AH1, NFI_SHIDS  ;  Q0SY02, NFI_SHIF8  ;  Q83MJ0, NFI_SHIFL  ;
DR   Q2NWR1, NFI_SODGM  ;  Q82MH6, NFI_STRAW  ;  Q9X7N2, NFI_STRCO  ;
DR   Q4JB89, NFI_SULAC  ;  C3N187, NFI_SULIA  ;  C4KKT0, NFI_SULIK  ;
DR   C3MKC9, NFI_SULIL  ;  C3MU99, NFI_SULIM  ;  C3NMU5, NFI_SULIN  ;
DR   C3N977, NFI_SULIY  ;  Q97VZ6, NFI_SULSO  ;  Q974T1, NFI_SULTO  ;
DR   Q9HKY3, NFI_THEAC  ;  A6LNA6, NFI_THEM4  ;  Q9X2H9, NFI_THEMA  ;
DR   B9K7P3, NFI_THENN  ;  A5IL77, NFI_THEP1  ;  A1RY04, NFI_THEPD  ;
DR   B1LAF7, NFI_THESQ  ;  Q72IZ9, NFI_THET2  ;  Q5SIM2, NFI_THET8  ;
DR   Q97AL5, NFI_THEVO  ;  Q8PIM0, NFI_XANAC  ;  Q3BR52, NFI_XANC5  ;
DR   Q4UWV2, NFI_XANC8  ;  B0RQR6, NFI_XANCB  ;  Q8P7A0, NFI_XANCP  ;
DR   Q2P5R1, NFI_XANOM  ;  B2SRM7, NFI_XANOP  ;  Q9PC89, NFI_XYLFA  ;
DR   Q87CZ0, NFI_XYLFT  ;  A1JIJ2, NFI_YERE8  ;  A7FNH1, NFI_YERP3  ;
DR   Q8ZAQ8, NFI_YERPE  ;  Q66FP0, NFI_YERPS  ;
//
ID   3.1.22.1
DE   Deoxyribonuclease II.
AN   DNase II.
AN   Lysosomal DNase II.
CA   Endonucleolytic cleavage to nucleoside 3'-phosphates and
CA   3'-phosphooligonucleotide end-products.
CC   -!- Preference for double-stranded DNA.
CC   -!- Similar enzymes: crab testis DNase, snail DNase, salmon testis DNase,
CC       liver acid DNase, human acid DNases of gastric mucosa and cervix.
CC   -!- Formerly EC 3.1.4.6.
DR   Q75WF2, DNA2_ACAPL ;  P56541, DNS2A_BOVIN;  O00115, DNS2A_HUMAN;
DR   P56542, DNS2A_MOUSE;  O62855, DNS2A_PIG  ;  Q9QZK8, DNS2A_RAT  ;
DR   Q8WZ79, DNS2B_HUMAN;  Q9QY48, DNS2B_MOUSE;  Q9QZK9, DNS2B_RAT  ;
DR   Q17778, NUC1_CAEEL ;
//
ID   3.1.22.2
DE   Aspergillus deoxyribonuclease K(1).
AN   Aspergillus DNase K1.
CA   Endonucleolytic cleavage to nucleoside 3'-phosphates and
CA   3'-phosphooligonucleotide end-products.
CC   -!- Preference for single-stranded DNA.
//
ID   3.1.22.3
DE   Transferred entry: 3.1.21.7.
//
ID   3.1.22.4
DE   Crossover junction endodeoxyribonuclease.
AN   Crossover junction endoribonuclease.
AN   Cruciform-cutting endonuclease.
AN   Endo X3.
AN   Endonuclease RuvC.
AN   Endonuclease VII.
AN   Endonuclease X3.
AN   Hje endonuclease.
AN   Holliday junction endonuclease CCE1.
AN   Holliday junction nuclease.
AN   Holliday junction resolvase.
AN   Holliday junction-cleaving endonuclease.
AN   Holliday junction-resolving endoribonuclease.
AN   Resolving enzyme CCE1.
AN   RusA endonuclease.
AN   RusA Holliday junction resolvase.
AN   RuvC endonuclease.
AN   SpCCe1 Holliday junction resolvase.
CA   Endonucleolytic cleavage at a junction such as a reciprocal single-
CA   stranded crossover between two homologous DNA duplexes (Holliday
CA   junction).
CC   -!- The enzyme from Saccharomyces cerevisiae has no endonuclease or
CC       exonuclease activity on single-stranded or double-stranded DNA
CC       molecules that do not contain Holliday junctions.
PR   PROSITE; PDOC01025;
DR   O67766, RUSA_AQUAE ;  Q37873, RUSA_BP82  ;  Q9MCN8, RUSA_BPHK7 ;
DR   Q38100, RUSA_BPR1T ;  A7ZJG7, RUSA_ECO24 ;  Q8X707, RUSA_ECO57 ;
DR   A1AA51, RUSA_ECOK1 ;  Q0TIR3, RUSA_ECOL5 ;  P0AG75, RUSA_ECOL6 ;
DR   P0AG74, RUSA_ECOLI ;  Q1RCY4, RUSA_ECOUT ;  Q3YZH8, RUSA_SHISS ;
DR   B0C9S0, RUVC_ACAM1 ;  A1TKE3, RUVC_ACIAC ;  Q6FAQ2, RUVC_ACIAD ;
DR   B7H3S1, RUVC_ACIB3 ;  B7I4I7, RUVC_ACIB5 ;  B2HYY2, RUVC_ACIBC ;
DR   Q1IKI1, RUVC_ACIBL ;  B0VR37, RUVC_ACIBS ;  A3M4U7, RUVC_ACIBT ;
DR   B0VCA5, RUVC_ACIBY ;  A0LUK7, RUVC_ACIC1 ;  C1F130, RUVC_ACIC5 ;
DR   A5G2L4, RUVC_ACICJ ;  B9MFQ0, RUVC_ACIET ;  A1WBZ4, RUVC_ACISJ ;
DR   A3N1F7, RUVC_ACTP2 ;  B3GY41, RUVC_ACTP7 ;  A6VQA5, RUVC_ACTSZ ;
DR   A0KHU1, RUVC_AERHH ;  A4SKG7, RUVC_AERS4 ;  B9J9J2, RUVC_AGRRK ;
DR   Q8U9K4, RUVC_AGRT5 ;  B9JRI5, RUVC_AGRVS ;  B2UP63, RUVC_AKKM8 ;
DR   Q0VRJ9, RUVC_ALCBS ;  Q0A5Q4, RUVC_ALHEH ;  B6EGJ2, RUVC_ALISL ;
DR   A6TQM3, RUVC_ALKMQ ;  A8MHI5, RUVC_ALKOO ;  B8JF03, RUVC_ANAD2 ;
DR   Q2IPJ7, RUVC_ANADE ;  A7H905, RUVC_ANADF ;  B9KH95, RUVC_ANAMF ;
DR   Q5P9D7, RUVC_ANAMM ;  Q2GLU6, RUVC_ANAPZ ;  B4UFX9, RUVC_ANASK ;
DR   Q3MGZ5, RUVC_ANAVT ;  A8EX70, RUVC_ARCB4 ;  Q5P3C5, RUVC_AROAE ;
DR   A1R726, RUVC_ARTAT ;  B8H9D8, RUVC_ARTCA ;  A0JXB3, RUVC_ARTS2 ;
DR   A8IM96, RUVC_AZOC5 ;  A1K2Y3, RUVC_AZOSB ;  C1DRG0, RUVC_AZOVD ;
DR   Q5LAS7, RUVC_BACFN ;  A1UR86, RUVC_BARBK ;  Q6G5Q9, RUVC_BARHE ;
DR   Q6FYP4, RUVC_BARQU ;  A9IYK9, RUVC_BART1 ;  Q1LTF1, RUVC_BAUCH ;
DR   Q6MKB6, RUVC_BDEBA ;  B2IAW3, RUVC_BEII9 ;  B8DUE9, RUVC_BIFA0 ;
DR   A1A1K1, RUVC_BIFAA ;  B3DRX8, RUVC_BIFLD ;  Q8G6B9, RUVC_BIFLO ;
DR   B7GR16, RUVC_BIFLS ;  Q2KVY8, RUVC_BORA1 ;  Q7WGB7, RUVC_BORBR ;
DR   Q7W4U0, RUVC_BORPA ;  A9I8F5, RUVC_BORPD ;  Q7VTU0, RUVC_BORPE ;
DR   A1QYH7, RUVC_BORT9 ;  C0R1L6, RUVC_BRAHW ;  Q89U82, RUVC_BRAJA ;
DR   A5ERK2, RUVC_BRASB ;  A4YMC5, RUVC_BRASO ;  C0ZAN2, RUVC_BREBN ;
DR   B2S7E1, RUVC_BRUA1 ;  Q2YRD0, RUVC_BRUA2 ;  Q57BH6, RUVC_BRUAB ;
DR   A9M7K2, RUVC_BRUC2 ;  C0REW7, RUVC_BRUMB ;  Q8YIV7, RUVC_BRUME ;
DR   A5VS60, RUVC_BRUO2 ;  A9WWI1, RUVC_BRUSI ;  Q8FZ01, RUVC_BRUSU ;
DR   B1YTE1, RUVC_BURA4 ;  Q1BZ34, RUVC_BURCA ;  B1JVV5, RUVC_BURCC ;
DR   A0K4L6, RUVC_BURCH ;  B4EES5, RUVC_BURCJ ;  Q0BI81, RUVC_BURCM ;
DR   A9AH71, RUVC_BURM1 ;  A3MP74, RUVC_BURM7 ;  Q62HA7, RUVC_BURMA ;
DR   A3NZ65, RUVC_BURP0 ;  Q3JNS7, RUVC_BURP1 ;  A3NDF4, RUVC_BURP6 ;
DR   B2JGU2, RUVC_BURP8 ;  B2SYJ9, RUVC_BURPP ;  Q63QX7, RUVC_BURPS ;
DR   Q39JI9, RUVC_BURS3 ;  Q2SZ53, RUVC_BURTA ;  A4JBL4, RUVC_BURVG ;
DR   Q13UC2, RUVC_BURXL ;  A4XJS1, RUVC_CALS8 ;  A7ZGE5, RUVC_CAMC1 ;
DR   A7H193, RUVC_CAMC5 ;  A0RRU6, RUVC_CAMFF ;  A7I463, RUVC_CAMHC ;
DR   A8FP40, RUVC_CAMJ8 ;  A7H674, RUVC_CAMJD ;  Q9PLU8, RUVC_CAMJE ;
DR   A1W1Y1, RUVC_CAMJJ ;  Q5HS68, RUVC_CAMJR ;  B9KE83, RUVC_CAMLR ;
DR   Q3ABX8, RUVC_CARHZ ;  Q9A3G6, RUVC_CAUCR ;  B0SUN7, RUVC_CAUSK ;
DR   A9WIH6, RUVC_CHLAA ;  Q5L6Z4, RUVC_CHLAB ;  B8G4I8, RUVC_CHLAD ;
DR   Q3AU83, RUVC_CHLCH ;  Q824M6, RUVC_CHLCV ;  Q252X9, RUVC_CHLFF ;
DR   B3EG36, RUVC_CHLL2 ;  Q9PJN9, RUVC_CHLMU ;  B3QLZ5, RUVC_CHLP8 ;
DR   A1BDW9, RUVC_CHLPD ;  Q9Z7T3, RUVC_CHLPN ;  B9LAL7, RUVC_CHLSY ;
DR   B0B876, RUVC_CHLT2 ;  B3QTP6, RUVC_CHLT3 ;  Q3KLJ5, RUVC_CHLTA ;
DR   B0BCE1, RUVC_CHLTB ;  Q8KBW8, RUVC_CHLTE ;  O84510, RUVC_CHLTR ;
DR   Q1QWG0, RUVC_CHRSD ;  Q7NQB5, RUVC_CHRVO ;  A8AFH8, RUVC_CITK8 ;
DR   A5CS08, RUVC_CLAM3 ;  B0REB8, RUVC_CLAMS ;  B8I1A2, RUVC_CLOCE ;
DR   Q183P3, RUVC_CLOD6 ;  A3DBU2, RUVC_CLOTH ;  Q483C6, RUVC_COLP3 ;
DR   Q6NGX3, RUVC_CORDI ;  Q8FPK3, RUVC_COREF ;  Q9AE11, RUVC_CORGL ;
DR   Q4JVD7, RUVC_CORJK ;  B6J504, RUVC_COXB1 ;  B6IYU4, RUVC_COXB2 ;
DR   A9KF42, RUVC_COXBN ;  A9N9A1, RUVC_COXBR ;  Q83BE3, RUVC_COXBU ;
DR   Q0KEC1, RUVC_CUPNH ;  Q475R5, RUVC_CUPPJ ;  B2AH75, RUVC_CUPTR ;
DR   B8HX01, RUVC_CYAP4 ;  Q11T17, RUVC_CYTH3 ;  Q478E2, RUVC_DECAR ;
DR   Q3Z9B2, RUVC_DEHE1 ;  A5FS25, RUVC_DEHSB ;  Q3ZZK5, RUVC_DEHSC ;
DR   Q1J1K4, RUVC_DEIGD ;  Q9RX75, RUVC_DEIRA ;  A9BUL6, RUVC_DELAS ;
DR   Q30YX5, RUVC_DESDG ;  B8FQV7, RUVC_DESHD ;  Q24UN5, RUVC_DESHY ;
DR   C4XIK0, RUVC_DESMR ;  A4J535, RUVC_DESRM ;  Q729U1, RUVC_DESVH ;
DR   A1VC42, RUVC_DESVV ;  A5EXG1, RUVC_DICNV ;  B5YFL3, RUVC_DICT6 ;
DR   B8E2P3, RUVC_DICTD ;  A8LHP8, RUVC_DINSH ;  A7ZMY7, RUVC_ECO24 ;
DR   B7USP0, RUVC_ECO27 ;  B7MBS2, RUVC_ECO45 ;  B7L7R6, RUVC_ECO55 ;
DR   P0A816, RUVC_ECO57 ;  B5YR08, RUVC_ECO5E ;  B7NS55, RUVC_ECO7I ;
DR   B7MVZ4, RUVC_ECO81 ;  B7M2F4, RUVC_ECO8A ;  C4ZQE7, RUVC_ECOBW ;
DR   B1XHD1, RUVC_ECODH ;  A8A163, RUVC_ECOHS ;  A1AC24, RUVC_ECOK1 ;
DR   Q0TGW9, RUVC_ECOL5 ;  P0A815, RUVC_ECOL6 ;  B1J0M5, RUVC_ECOLC ;
DR   P0A814, RUVC_ECOLI ;  B7NBL4, RUVC_ECOLU ;  B6IBU2, RUVC_ECOSE ;
DR   B1LD08, RUVC_ECOSM ;  Q1RAS1, RUVC_ECOUT ;  C5B9T0, RUVC_EDWI9 ;
DR   Q3YT96, RUVC_EHRCJ ;  Q2GI72, RUVC_EHRCR ;  Q5FF10, RUVC_EHRRG ;
DR   Q5HCG1, RUVC_EHRRW ;  A4WBM0, RUVC_ENT38 ;  A7MEA1, RUVC_ENTS8 ;
DR   Q6D4A0, RUVC_ERWCT ;  B2VJ93, RUVC_ERWT9 ;  Q2N5P5, RUVC_ERYLH ;
DR   B7LPI1, RUVC_ESCF3 ;  A7HNS2, RUVC_FERNB ;  B0S1J5, RUVC_FINM2 ;
DR   Q0RNU8, RUVC_FRAAA ;  B0TZD9, RUVC_FRAP2 ;  Q2JD96, RUVC_FRASC ;
DR   A8KZE8, RUVC_FRASN ;  Q14IH0, RUVC_FRAT1 ;  A7NBV3, RUVC_FRATF ;
DR   Q2A3Q9, RUVC_FRATH ;  B2SH69, RUVC_FRATM ;  A0Q6P9, RUVC_FRATN ;
DR   Q0BM65, RUVC_FRATO ;  Q5NH18, RUVC_FRATT ;  A4IY87, RUVC_FRATW ;
DR   Q8RGS0, RUVC_FUSNN ;  B5EAH1, RUVC_GEOBB ;  B3E789, RUVC_GEOLS ;
DR   Q39XN8, RUVC_GEOMG ;  B9LZC6, RUVC_GEOSF ;  Q74E88, RUVC_GEOSL ;
DR   C6E1T0, RUVC_GEOSM ;  A5G9Y4, RUVC_GEOUR ;  Q7NG73, RUVC_GLOVI ;
DR   A9HAV5, RUVC_GLUDA ;  Q5FQC6, RUVC_GLUOX ;  Q0BT56, RUVC_GRABC ;
DR   A0LXG7, RUVC_GRAFK ;  Q7VNF5, RUVC_HAEDU ;  Q4QNM4, RUVC_HAEI8 ;
DR   A5UAH6, RUVC_HAEIE ;  A5UGD0, RUVC_HAEIG ;  P44633, RUVC_HAEIN ;
DR   B8F5G6, RUVC_HAEPS ;  Q0I243, RUVC_HAES1 ;  Q2SCL1, RUVC_HAHCH ;
DR   A1WZ63, RUVC_HALHL ;  B8CXG4, RUVC_HALOH ;  C4K4U7, RUVC_HAMD5 ;
DR   Q17WI2, RUVC_HELAH ;  Q7VH56, RUVC_HELHP ;  B0TF68, RUVC_HELMI ;
DR   B6JMA1, RUVC_HELP2 ;  B5Z7N7, RUVC_HELPG ;  Q1CSZ5, RUVC_HELPH ;
DR   Q9ZKX3, RUVC_HELPJ ;  B2USV3, RUVC_HELPS ;  O25544, RUVC_HELPY ;
DR   A4G1U7, RUVC_HERAR ;  Q0C5W4, RUVC_HYPNA ;  Q5QYV0, RUVC_IDILO ;
DR   A6SUQ2, RUVC_JANMA ;  B5XQ03, RUVC_KLEP3 ;  A6TB32, RUVC_KLEP7 ;
DR   Q1MRQ2, RUVC_LAWIP ;  Q5X5S0, RUVC_LEGPA ;  A5IBE0, RUVC_LEGPC ;
DR   Q5ZW01, RUVC_LEGPH ;  Q5WX48, RUVC_LEGPL ;  Q6AFB6, RUVC_LEIXX ;
DR   Q2W2A2, RUVC_MAGSA ;  A0L4W0, RUVC_MAGSM ;  Q65UP2, RUVC_MANSM ;
DR   A1U1C1, RUVC_MARAV ;  Q0ALX7, RUVC_MARMM ;  Q11DH4, RUVC_MESSB ;
DR   B7L253, RUVC_METC4 ;  Q609L2, RUVC_METCA ;  A9W1B1, RUVC_METEP ;
DR   Q1GYR6, RUVC_METFK ;  B1Z922, RUVC_METPB ;  A2SD05, RUVC_METPP ;
DR   B1LZP2, RUVC_METRJ ;  B8EJI4, RUVC_METSB ;  Q2RHT5, RUVC_MOOTA ;
DR   A0QIB9, RUVC_MYCA1 ;  P66761, RUVC_MYCBO ;  A1KLU2, RUVC_MYCBP ;
DR   C1AF63, RUVC_MYCBT ;  P40834, RUVC_MYCLE ;  B2HN61, RUVC_MYCMM ;
DR   Q741Q2, RUVC_MYCPA ;  A0QWH4, RUVC_MYCS2 ;  A3PYW3, RUVC_MYCSJ ;
DR   A1UFA2, RUVC_MYCSK ;  Q1B9R1, RUVC_MYCSS ;  A5U5U4, RUVC_MYCTA ;
DR   P66760, RUVC_MYCTU ;  A0PPD1, RUVC_MYCUA ;  A1T882, RUVC_MYCVP ;
DR   Q1D2J4, RUVC_MYXXD ;  B2A5L6, RUVC_NATTJ ;  B9L734, RUVC_NAUPA ;
DR   Q5FA76, RUVC_NEIG1 ;  A9M0D4, RUVC_NEIM0 ;  Q9JTU3, RUVC_NEIMA ;
DR   Q9JYV1, RUVC_NEIMB ;  A1KUM5, RUVC_NEIMF ;  Q2GCH7, RUVC_NEOSM ;
DR   Q0AJA5, RUVC_NITEC ;  Q82XP5, RUVC_NITEU ;  Q1QHP5, RUVC_NITHX ;
DR   Q3JES5, RUVC_NITOC ;  A6Q652, RUVC_NITSB ;  Q3SP12, RUVC_NITWN ;
DR   Q5YTE6, RUVC_NOCFA ;  A1SJA5, RUVC_NOCSJ ;  B2J4H5, RUVC_NOSP7 ;
DR   O52751, RUVC_NOSS1 ;  Q2GBA4, RUVC_NOVAD ;  A6WY74, RUVC_OCHA4 ;
DR   B6JIZ7, RUVC_OLICO ;  A5CES8, RUVC_ORITB ;  B3CSI0, RUVC_ORITI ;
DR   A1AZW4, RUVC_PARDP ;  A7HUZ6, RUVC_PARL1 ;  Q6MFA6, RUVC_PARUW ;
DR   P57894, RUVC_PASMU ;  C6DFF0, RUVC_PECCP ;  Q3A232, RUVC_PELCD ;
DR   Q3B2D5, RUVC_PELLD ;  B4SDW6, RUVC_PELPB ;  A1ASF5, RUVC_PELPD ;
DR   A5D3F9, RUVC_PELTS ;  A9BIM4, RUVC_PETMO ;  Q7N549, RUVC_PHOLL ;
DR   Q6LT51, RUVC_PHOPR ;  A1VSS8, RUVC_POLNA ;  B1XS24, RUVC_POLNS ;
DR   Q12EK7, RUVC_POLSJ ;  A4T026, RUVC_POLSQ ;  B2RJT7, RUVC_PORG3 ;
DR   Q7MUZ6, RUVC_PORGI ;  B4S5F6, RUVC_PROA2 ;  Q6A8K9, RUVC_PROAC ;
DR   A3PDF8, RUVC_PROM0 ;  A2C3N0, RUVC_PROM1 ;  A8G5C3, RUVC_PROM2 ;
DR   A2C835, RUVC_PROM3 ;  A9BB56, RUVC_PROM4 ;  A2BX41, RUVC_PROM5 ;
DR   Q31AH1, RUVC_PROM9 ;  Q7VBE8, RUVC_PROMA ;  B4ETP6, RUVC_PROMH ;
DR   Q7V6L9, RUVC_PROMM ;  Q7V132, RUVC_PROMP ;  A2BRN2, RUVC_PROMS ;
DR   Q46JY8, RUVC_PROMT ;  A4SG33, RUVC_PROVI ;  Q48FC3, RUVC_PSE14 ;
DR   Q15RN4, RUVC_PSEA6 ;  A6VA07, RUVC_PSEA7 ;  B7UXW7, RUVC_PSEA8 ;
DR   Q02IC7, RUVC_PSEAB ;  Q51424, RUVC_PSEAE ;  Q1I6E7, RUVC_PSEE4 ;
DR   Q4K7D7, RUVC_PSEF5 ;  C3JYS9, RUVC_PSEFS ;  Q3IIJ0, RUVC_PSEHT ;
DR   A4XRR9, RUVC_PSEMY ;  A5VZU5, RUVC_PSEP1 ;  Q3K7V8, RUVC_PSEPF ;
DR   B0KTJ4, RUVC_PSEPG ;  Q88NJ2, RUVC_PSEPK ;  B1JD72, RUVC_PSEPW ;
DR   Q87Y33, RUVC_PSESM ;  Q4ZWL3, RUVC_PSEU2 ;  A4VNA5, RUVC_PSEU5 ;
DR   Q4FTV0, RUVC_PSYA2 ;  Q1QCZ9, RUVC_PSYCK ;  A1SSV3, RUVC_PSYIN ;
DR   A5WFD7, RUVC_PSYWF ;  Q1LRB4, RUVC_RALME ;  B2UFL4, RUVC_RALPJ ;
DR   Q8Y233, RUVC_RALSO ;  A9WSE6, RUVC_RENSM ;  B3PYZ1, RUVC_RHIE6 ;
DR   Q2K4K2, RUVC_RHIEC ;  Q1MC56, RUVC_RHIL3 ;  Q98F72, RUVC_RHILO ;
DR   B5ZP76, RUVC_RHILW ;  Q92M90, RUVC_RHIME ;  C3MIH7, RUVC_RHISN ;
DR   Q7US71, RUVC_RHOBA ;  C0ZZ46, RUVC_RHOE4 ;  Q21SX7, RUVC_RHOFD ;
DR   C1B4C9, RUVC_RHOOB ;  Q07H95, RUVC_RHOP5 ;  Q6NAT1, RUVC_RHOPA ;
DR   Q20X08, RUVC_RHOPB ;  B3QHS1, RUVC_RHOPT ;  Q2RVF7, RUVC_RHORT ;
DR   A3PLU5, RUVC_RHOS1 ;  Q3J0F5, RUVC_RHOS4 ;  A4WRW7, RUVC_RHOS5 ;
DR   B9KKV7, RUVC_RHOSK ;  Q0S1C8, RUVC_RHOSR ;  C3PMF5, RUVC_RICAE ;
DR   A8GM81, RUVC_RICAH ;  A8GUZ9, RUVC_RICB8 ;  Q1RHA5, RUVC_RICBR ;
DR   Q92JA8, RUVC_RICCN ;  Q4UKB1, RUVC_RICFE ;  A8F0M4, RUVC_RICM5 ;
DR   Q9ZE29, RUVC_RICPR ;  C4K1R1, RUVC_RICPU ;  B0BW86, RUVC_RICRO ;
DR   A8GQU0, RUVC_RICRS ;  Q68XY7, RUVC_RICTY ;  A5V1E5, RUVC_ROSS1 ;
DR   Q1AWE2, RUVC_RUBXD ;  Q21HN4, RUVC_SACD2 ;  A4FBA6, RUVC_SACEN ;
DR   B5F3J2, RUVC_SALA4 ;  A8LXW7, RUVC_SALAI ;  A9MND5, RUVC_SALAR ;
DR   Q57N99, RUVC_SALCH ;  B5FSN3, RUVC_SALDC ;  B5R1V5, RUVC_SALEP ;
DR   B5R8D9, RUVC_SALG2 ;  B4T7Z6, RUVC_SALHS ;  B4SVE8, RUVC_SALNS ;
DR   Q5PN00, RUVC_SALPA ;  A9MUC2, RUVC_SALPB ;  C0Q2F1, RUVC_SALPC ;
DR   B5BH57, RUVC_SALPK ;  Q2RZ65, RUVC_SALRD ;  B4TYS1, RUVC_SALSV ;
DR   P66763, RUVC_SALTI ;  P66762, RUVC_SALTY ;  A8GFI9, RUVC_SERP5 ;
DR   A1S6P0, RUVC_SHEAM ;  B8EA73, RUVC_SHEB2 ;  A3D479, RUVC_SHEB5 ;
DR   A6WNQ4, RUVC_SHEB8 ;  A9L3H9, RUVC_SHEB9 ;  Q12N08, RUVC_SHEDO ;
DR   Q081N7, RUVC_SHEFN ;  B0TSA5, RUVC_SHEHH ;  A3QEP5, RUVC_SHELP ;
DR   Q8EEF1, RUVC_SHEON ;  A8H547, RUVC_SHEPA ;  A4Y6S7, RUVC_SHEPC ;
DR   B8CNX9, RUVC_SHEPW ;  A0KWL7, RUVC_SHESA ;  A8FUW8, RUVC_SHESH ;
DR   Q0HIZ3, RUVC_SHESM ;  Q0HUY9, RUVC_SHESR ;  A1RJQ4, RUVC_SHESW ;
DR   B1KHG5, RUVC_SHEWM ;  B2TXL5, RUVC_SHIB3 ;  Q322D7, RUVC_SHIBS ;
DR   Q32H98, RUVC_SHIDS ;  Q0T3U3, RUVC_SHIF8 ;  Q7UAE7, RUVC_SHIFL ;
DR   Q3Z2M1, RUVC_SHISS ;  Q5LNT6, RUVC_SILPO ;  A6UCT9, RUVC_SINMW ;
DR   Q2NTJ0, RUVC_SODGM ;  Q01TY0, RUVC_SOLUE ;  A9FR00, RUVC_SORC5 ;
DR   Q1GWB3, RUVC_SPHAL ;  A5V884, RUVC_SPHWW ;  Q820F5, RUVC_STRAW ;
DR   Q9L289, RUVC_STRCO ;  B1W3G2, RUVC_STRGG ;  B4ST35, RUVC_STRM5 ;
DR   B2FRN7, RUVC_STRMK ;  Q30NQ3, RUVC_SULDN ;  A6QD40, RUVC_SULNB ;
DR   Q67Q99, RUVC_SYMTH ;  Q31Q39, RUVC_SYNE7 ;  Q2JP15, RUVC_SYNJB ;
DR   Q5N440, RUVC_SYNP6 ;  A5GM62, RUVC_SYNPW ;  Q7U8A6, RUVC_SYNPX ;
DR   A5GRX2, RUVC_SYNR3 ;  Q0IBJ8, RUVC_SYNS3 ;  Q3AYZ7, RUVC_SYNS9 ;
DR   Q3AI88, RUVC_SYNSC ;  Q0AX14, RUVC_SYNWW ;  Q55506, RUVC_SYNY3 ;
DR   C5BQT6, RUVC_TERTT ;  B7ICN6, RUVC_THEAB ;  Q8DJT5, RUVC_THEEB ;
DR   Q47N41, RUVC_THEFY ;  A8F3S6, RUVC_THELT ;  A6LLU8, RUVC_THEM4 ;
DR   Q9WZ45, RUVC_THEMA ;  A5IJJ9, RUVC_THEP1 ;  B9KZ87, RUVC_THERP ;
DR   B1L8R9, RUVC_THESQ ;  Q72JP3, RUVC_THET2 ;  Q5SJC4, RUVC_THET8 ;
DR   Q8RAN4, RUVC_THETN ;  B5YJT8, RUVC_THEYD ;  Q31H85, RUVC_THICR ;
DR   Q3SGT0, RUVC_THIDA ;  C4LBN2, RUVC_TOLAT ;  Q73LJ8, RUVC_TREDE ;
DR   O83530, RUVC_TREPA ;  B2S3B1, RUVC_TREPS ;  Q10YI3, RUVC_TRIEI ;
DR   B1H0B2, RUVC_UNCTG ;  C5CNG5, RUVC_VARPS ;  A1WM26, RUVC_VEREI ;
DR   A5F762, RUVC_VIBC3 ;  Q9KR00, RUVC_VIBCH ;  C3LNF0, RUVC_VIBCM ;
DR   Q5E6A1, RUVC_VIBF1 ;  B5FCQ0, RUVC_VIBFM ;  A7N1J2, RUVC_VIBHB ;
DR   Q87QV1, RUVC_VIBPA ;  B7VMI1, RUVC_VIBSL ;  Q8DAN6, RUVC_VIBVU ;
DR   Q7MJ75, RUVC_VIBVY ;  Q8D387, RUVC_WIGBR ;  Q73IL5, RUVC_WOLPM ;
DR   B3CN07, RUVC_WOLPP ;  Q7M7L1, RUVC_WOLSU ;  Q5GRT9, RUVC_WOLTR ;
DR   C0R5C3, RUVC_WOLWR ;  Q8PHU9, RUVC_XANAC ;  Q3BQF1, RUVC_XANC5 ;
DR   Q4UXM1, RUVC_XANC8 ;  B0RPY3, RUVC_XANCB ;  Q8P6E4, RUVC_XANCP ;
DR   Q2P578, RUVC_XANOM ;  B2STK3, RUVC_XANOP ;  Q5H2A7, RUVC_XANOR ;
DR   A7IJV2, RUVC_XANP2 ;  Q9PC76, RUVC_XYLFA ;  Q87D03, RUVC_XYLFT ;
DR   A1JRK2, RUVC_YERE8 ;  A7FIC7, RUVC_YERP3 ;  Q1C817, RUVC_YERPA ;
DR   B2K322, RUVC_YERPB ;  Q8ZEU7, RUVC_YERPE ;  A9QYX5, RUVC_YERPG ;
DR   Q1CJG7, RUVC_YERPN ;  A4TJK2, RUVC_YERPP ;  Q66AU1, RUVC_YERPS ;
DR   B1JLL2, RUVC_YERPY ;  Q5NR76, RUVC_ZYMMO ;
//
ID   3.1.22.5
DE   Deoxyribonuclease X.
CA   Endonucleolytic cleavage of supercoiled plasma DNA to linear DNA
CA   duplexes.
CC   -!- Preference for supercoiled DNA; little activity on linear double-
CC       stranded DNA.
CC   -!- Inhibited by single-stranded DNA, ATP and AMP.
//
ID   3.1.23.1
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.2
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.3
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.4
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.5
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.6
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.7
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.8
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.9
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.10
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.11
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.12
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.13
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.14
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.15
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.16
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.17
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.18
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.19
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.20
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.21
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.22
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.23
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.24
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.25
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.26
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.27
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.28
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.29
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.30
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.31
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.32
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.33
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.34
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.35
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.36
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.37
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.38
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.39
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.40
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.41
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.42
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.43
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.44
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.45
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.46
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.47
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.48
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.49
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.50
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.51
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.52
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.53
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.54
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.55
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.56
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.57
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.58
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.23.59
DE   Transferred entry: 3.1.21.4.
//
ID   3.1.24.1
DE   Transferred entry: 3.1.21.3.
//
ID   3.1.24.2
DE   Transferred entry: 3.1.21.3.
//
ID   3.1.24.3
DE   Transferred entry: 3.1.21.5.
//
ID   3.1.24.4
DE   Transferred entry: 3.1.21.5.
//
ID   3.1.25.1
DE   Deoxyribonuclease (pyrimidine dimer).
AN   Endodeoxyribonuclease (pyrimidine dimer).
CA   Endonucleolytic cleavage near pyrimidine dimers to products with
CA   5'-phosphate.
CC   -!- Acts on a damaged strand, 5' from the damaged site.
CC   -!- Similar enzymes: T4 endonuclease V, Escherichia coli endonuclease III
CC       and V, correndonuclease II.
DR   P04418, END5_BPT4  ;
//
ID   3.1.25.2
DE   Transferred entry: 4.2.99.18.
//
ID   3.1.26.1
DE   Physarum polycephalum ribonuclease.
CA   Endonucleolytic cleavage to 5'-phosphomonoester.
//
ID   3.1.26.2
DE   Ribonuclease alpha.
CA   Endonucleolytic cleavage to 5'-phosphomonoester.
CC   -!- Specific for O-methylated RNA.
//
ID   3.1.26.3
DE   Ribonuclease III.
AN   Ribonuclease 3.
AN   RNase III.
CA   Endonucleolytic cleavage to 5'-phosphomonoester.
CC   -!- An endoribonuclease that cleaves double-stranded RNA molecules.
CC   -!- The cleavage can be either a single-stranded nick or double-stranded
CC       break in the RNA, depending in part upon the degree of base-pairing
CC       in the region of the cleavage site.
CC   -!- Specificity is conferred by negative determinants, i.e., the presence
CC       of certain Watson-Crick base-pairs at specific positions that
CC       strongly inhibit cleavage.
CC   -!- RNase III is involved in both rRNA processing and mRNA processing and
CC       decay.
PR   PROSITE; PDOC00448;
DR   P22192, PAC1_SCHPO ;  P74368, RNC1_SYNY3 ;  Q55637, RNC2_SYNY3 ;
DR   Q6F9C2, RNC_ACIAD  ;  B0VTM5, RNC_ACIBS  ;  A3M7P2, RNC_ACIBT  ;
DR   B0VCU0, RNC_ACIBY  ;  A3MZQ9, RNC_ACTP2  ;  B0BUA6, RNC_ACTPJ  ;
DR   A6VLV8, RNC_ACTSZ  ;  B9JC73, RNC_AGRRK  ;  Q8UGK2, RNC_AGRT5  ;
DR   B9JUN7, RNC_AGRVS  ;  Q0VP19, RNC_ALCBS  ;  Q0A8Z1, RNC_ALHEH  ;
DR   B9KGT5, RNC_ANAMF  ;  Q5P9U8, RNC_ANAMM  ;  Q2GIW0, RNC_ANAPZ  ;
DR   B7GGE9, RNC_ANOFW  ;  O67082, RNC_AQUAE  ;  A8EV88, RNC_ARCB4  ;
DR   Q5P086, RNC_AROAE  ;  Q2NJY3, RNC_AYWBP  ;  A8I3B5, RNC_AZOC5  ;
DR   B6YQI6, RNC_AZOPC  ;  C1DQS2, RNC_AZOVD  ;  A7Z4L3, RNC_BACA2  ;
DR   C3P5Q0, RNC_BACAA  ;  C3L778, RNC_BACAC  ;  Q81WI8, RNC_BACAN  ;
DR   B7JJT6, RNC_BACC0  ;  Q732M1, RNC_BACC1  ;  B7IUK8, RNC_BACC2  ;
DR   C1EP73, RNC_BACC3  ;  B7HDX2, RNC_BACC4  ;  B7HLI2, RNC_BACC7  ;
DR   A7GRH9, RNC_BACCN  ;  B9IVD8, RNC_BACCQ  ;  Q819V8, RNC_BACCR  ;
DR   Q636H7, RNC_BACCZ  ;  Q5LIS2, RNC_BACFN  ;  Q64ZV9, RNC_BACFR  ;
DR   Q9KA05, RNC_BACHD  ;  Q6HEW6, RNC_BACHK  ;  Q65JQ5, RNC_BACLD  ;
DR   Q5WFM6, RNC_BACSK  ;  P51833, RNC_BACSU  ;  Q8A2E8, RNC_BACTN  ;
DR   A6KZ76, RNC_BACV8  ;  A9VT87, RNC_BACWK  ;  A1US36, RNC_BARBK  ;
DR   Q6G459, RNC_BARHE  ;  Q6G082, RNC_BARQU  ;  A9IRN0, RNC_BART1  ;
DR   Q6MLR5, RNC_BDEBA  ;  Q8G7H1, RNC_BIFLO  ;  Q7VRR0, RNC_BLOFL  ;
DR   Q492D1, RNC_BLOPB  ;  Q2KWY0, RNC_BORA1  ;  Q0SMF0, RNC_BORAP  ;
DR   Q7WD32, RNC_BORBR  ;  O51648, RNC_BORBU  ;  Q660G7, RNC_BORGA  ;
DR   Q7W5J6, RNC_BORPA  ;  A9IIJ2, RNC_BORPD  ;  Q7VW39, RNC_BORPE  ;
DR   O69161, RNC_BRAJA  ;  B2SAD9, RNC_BRUA1  ;  Q2YN02, RNC_BRUA2  ;
DR   Q57E81, RNC_BRUAB  ;  A9MA35, RNC_BRUC2  ;  C0RI03, RNC_BRUMB  ;
DR   P66664, RNC_BRUME  ;  B0CKY7, RNC_BRUSI  ;  P66665, RNC_BRUSU  ;
DR   B8D951, RNC_BUCA5  ;  P57346, RNC_BUCAI  ;  Q8K9R1, RNC_BUCAP  ;
DR   B8D7F5, RNC_BUCAT  ;  P59476, RNC_BUCBP  ;  Q057R4, RNC_BUCCC  ;
DR   Q61XX9, RNC_CAEBR  ;  O01326, RNC_CAEEL  ;  A8Z6F6, RNC_CAMC1  ;
DR   A7H186, RNC_CAMC5  ;  A0RRM7, RNC_CAMFF  ;  A8FNU7, RNC_CAMJ8  ;
DR   A7H5Y2, RNC_CAMJD  ;  Q9PM40, RNC_CAMJE  ;  Q5HSF8, RNC_CAMJR  ;
DR   Q3AC58, RNC_CARHZ  ;  B8H627, RNC_CAUCN  ;  Q9A805, RNC_CAUCR  ;
DR   B0T3I0, RNC_CAUSK  ;  A9WJ69, RNC_CHLAA  ;  Q5L6E3, RNC_CHLAB  ;
DR   B8GAM6, RNC_CHLAD  ;  Q3AQ14, RNC_CHLCH  ;  Q823R4, RNC_CHLCV  ;
DR   Q253V2, RNC_CHLFF  ;  Q9PK97, RNC_CHLMU  ;  Q9Z9C7, RNC_CHLPN  ;
DR   B9LB70, RNC_CHLSY  ;  B0B7L3, RNC_CHLT2  ;  Q3KM65, RNC_CHLTA  ;
DR   B0BBS8, RNC_CHLTB  ;  Q8KAN7, RNC_CHLTE  ;  O84299, RNC_CHLTR  ;
DR   Q7NWC4, RNC_CHRVO  ;  Q97IA4, RNC_CLOAB  ;  A6LSM2, RNC_CLOB8  ;
DR   B2V4D6, RNC_CLOBA  ;  B2TJ22, RNC_CLOBB  ;  B9E1G8, RNC_CLOK1  ;
DR   A5N807, RNC_CLOK5  ;  Q8XJN8, RNC_CLOPE  ;  Q895M9, RNC_CLOTE  ;
DR   Q47WP5, RNC_COLP3  ;  Q6NGH3, RNC_CORDI  ;  Q8FP16, RNC_COREF  ;
DR   Q8NNV6, RNC_CORGL  ;  Q4JUY7, RNC_CORJK  ;  B6J4J9, RNC_COXB1  ;
DR   B6IYZ9, RNC_COXB2  ;  A9KFA0, RNC_COXBN  ;  A9N942, RNC_COXBR  ;
DR   P51837, RNC_COXBU  ;  Q0K8N3, RNC_CUPNH  ;  Q46Z18, RNC_CUPPJ  ;
DR   B3R1Z9, RNC_CUPTR  ;  Q47EF7, RNC_DECAR  ;  Q3Z7Q8, RNC_DEHE1  ;
DR   Q3ZXY9, RNC_DEHSC  ;  A9BNJ5, RNC_DELAS  ;  Q310Z1, RNC_DESDG  ;
DR   Q6ANV0, RNC_DESPS  ;  A4J683, RNC_DESRM  ;  Q72C44, RNC_DESVH  ;
DR   B8DPB3, RNC_DESVM  ;  A8LLD9, RNC_DINSH  ;  A7ZQ11, RNC_ECO24  ;
DR   B7UH07, RNC_ECO27  ;  B7MIQ2, RNC_ECO45  ;  B7LDG0, RNC_ECO55  ;
DR   P0A7Y2, RNC_ECO57  ;  B5Z141, RNC_ECO5E  ;  B7NRM0, RNC_ECO7I  ;
DR   B7MYJ8, RNC_ECO81  ;  B7M8I0, RNC_ECO8A  ;  C4ZYJ0, RNC_ECOBW  ;
DR   B1XB41, RNC_ECODH  ;  A8A377, RNC_ECOHS  ;  A1AE97, RNC_ECOK1  ;
DR   Q0TES1, RNC_ECOL5  ;  P0A7Y1, RNC_ECOL6  ;  B1IVR0, RNC_ECOLC  ;
DR   P0A7Y0, RNC_ECOLI  ;  B7N6F5, RNC_ECOLU  ;  B6I5E1, RNC_ECOSE  ;
DR   B1LP80, RNC_ECOSM  ;  Q1R8G6, RNC_ECOUT  ;  C5B8Y2, RNC_EDWI9  ;
DR   Q3YQX7, RNC_EHRCJ  ;  Q2GFE4, RNC_EHRCR  ;  Q5FGH0, RNC_EHRRG  ;
DR   Q5HA74, RNC_EHRRW  ;  A4WDD8, RNC_ENT38  ;  Q82ZG1, RNC_ENTFA  ;
DR   Q6D219, RNC_ERWCT  ;  B2VI46, RNC_ERWT9  ;  B7LUZ7, RNC_ESCF3  ;
DR   B0TXH8, RNC_FRAP2  ;  Q14G66, RNC_FRAT1  ;  A7NAR0, RNC_FRATF  ;
DR   Q2A4N2, RNC_FRATH  ;  B2SFY4, RNC_FRATM  ;  A0Q7W6, RNC_FRATN  ;
DR   Q0BN07, RNC_FRATO  ;  Q5NER3, RNC_FRATT  ;  A4IWK9, RNC_FRATW  ;
DR   Q6GZP5, RNC_FRG3G  ;  Q8RGX3, RNC_FUSNN  ;  Q5L0Q3, RNC_GEOKA  ;
DR   Q39T82, RNC_GEOMG  ;  Q74AX1, RNC_GEOSL  ;  C5D8T6, RNC_GEOSW  ;
DR   A4IM67, RNC_GEOTN  ;  Q7VL75, RNC_HAEDU  ;  Q4QPN0, RNC_HAEI8  ;
DR   A5UBC4, RNC_HAEIE  ;  A5UFI8, RNC_HAEIG  ;  P44441, RNC_HAEIN  ;
DR   B8F3C7, RNC_HAEPS  ;  B0USS1, RNC_HAES2  ;  Q2SL32, RNC_HAHCH  ;
DR   C4K3Z3, RNC_HAMD5  ;  Q17XJ6, RNC_HELAH  ;  Q7VIA9, RNC_HELHP  ;
DR   B0TGW4, RNC_HELMI  ;  B6JLQ0, RNC_HELP2  ;  B5Z735, RNC_HELPG  ;
DR   Q9ZLH2, RNC_HELPJ  ;  B2UTG4, RNC_HELPS  ;  P56118, RNC_HELPY  ;
DR   Q9NRR4, RNC_HUMAN  ;  B4U7T8, RNC_HYDS0  ;  Q5R106, RNC_IDILO  ;
DR   Q196V9, RNC_IIV3   ;  O55748, RNC_IIV6   ;  Q28V23, RNC_JANSC  ;
DR   B5XNH0, RNC_KLEP3  ;  A6TCI1, RNC_KLEP7  ;  Q5FJJ7, RNC_LACAC  ;
DR   B2GD42, RNC_LACF3  ;  Q74IP8, RNC_LACJO  ;  Q9CHD0, RNC_LACLA  ;
DR   A2RLZ8, RNC_LACLM  ;  Q030F9, RNC_LACLS  ;  Q88WK0, RNC_LACPL  ;
DR   A5VKP2, RNC_LACRD  ;  B2G826, RNC_LACRJ  ;  Q1WUA0, RNC_LACS1  ;
DR   Q38XR8, RNC_LACSS  ;  Q5X446, RNC_LEGPA  ;  A5ID21, RNC_LEGPC  ;
DR   Q5ZUD5, RNC_LEGPH  ;  Q5WVI4, RNC_LEGPL  ;  Q6AFJ4, RNC_LEIXX  ;
DR   Q04R64, RNC_LEPBJ  ;  Q053L4, RNC_LEPBL  ;  Q75FW5, RNC_LEPIC  ;
DR   Q8EXX3, RNC_LEPIN  ;  B1N016, RNC_LEUCK  ;  Q03VW5, RNC_LEUMM  ;
DR   Q92AK3, RNC_LISIN  ;  C1KWA4, RNC_LISMC  ;  Q71YL2, RNC_LISMF  ;
DR   B8DDU8, RNC_LISMH  ;  Q8Y691, RNC_LISMO  ;  A0AJR0, RNC_LISW6  ;
DR   A0L633, RNC_MAGSM  ;  Q65VN5, RNC_MANSM  ;  A6VUP6, RNC_MARMS  ;
DR   Q6F1N5, RNC_MESFL  ;  Q608M7, RNC_METCA  ;  B8EK13, RNC_METSB  ;
DR   Q5UQT7, RNC_MIMIV  ;  Q2RJX2, RNC_MOOTA  ;  Q5HZJ0, RNC_MOUSE  ;
DR   P66667, RNC_MYCBO  ;  Q2SRZ8, RNC_MYCCT  ;  P47607, RNC_MYCGE  ;
DR   O69469, RNC_MYCLE  ;  Q6KHN3, RNC_MYCMO  ;  Q6MTC9, RNC_MYCMS  ;
DR   Q73VL8, RNC_MYCPA  ;  P75233, RNC_MYCPN  ;  Q4A589, RNC_MYCS5  ;
DR   P66666, RNC_MYCTU  ;  Q1D5X9, RNC_MYXXD  ;  B2A2N1, RNC_NATTJ  ;
DR   Q5F9X7, RNC_NEIG1  ;  B4RJT7, RNC_NEIG2  ;  Q9JVD3, RNC_NEIMA  ;
DR   Q9K0C8, RNC_NEIMB  ;  Q0AF70, RNC_NITEC  ;  Q820I0, RNC_NITEU  ;
DR   Q3J8D5, RNC_NITOC  ;  A6Q1H0, RNC_NITSB  ;  Q3SRB3, RNC_NITWN  ;
DR   Q5YS08, RNC_NOCFA  ;  Q8Z023, RNC_NOSS1  ;  Q8ER05, RNC_OCEIH  ;
DR   Q04GL2, RNC_OENOB  ;  Q6YPW7, RNC_ONYPE  ;  Q6MEK1, RNC_PARUW  ;
DR   P57805, RNC_PASMU  ;  C6DC00, RNC_PECCP  ;  Q03FX0, RNC_PEDPA  ;
DR   Q3A4Q8, RNC_PELCD  ;  Q3B6L3, RNC_PELLD  ;  A5D1H6, RNC_PELTS  ;
DR   Q4FLS9, RNC_PELUB  ;  B4RCU4, RNC_PHEZH  ;  Q7N1X5, RNC_PHOLL  ;
DR   Q6LMS2, RNC_PHOPR  ;  B3R075, RNC_PHYMT  ;  B4F047, RNC_PROMH  ;
DR   Q48EV3, RNC_PSE14  ;  A6VAK6, RNC_PSEA7  ;  B7UYX2, RNC_PSEA8  ;
DR   Q02HS2, RNC_PSEAB  ;  Q9XCX9, RNC_PSEAE  ;  Q1I5V8, RNC_PSEE4  ;
DR   Q4KHT1, RNC_PSEF5  ;  C3K6Y7, RNC_PSEFS  ;  Q3IDL2, RNC_PSEHT  ;
DR   A4XSC4, RNC_PSEMY  ;  A5W8F2, RNC_PSEP1  ;  Q3KHL9, RNC_PSEPF  ;
DR   B0KV27, RNC_PSEPG  ;  Q88MY5, RNC_PSEPK  ;  B1J4E0, RNC_PSEPW  ;
DR   Q87XG1, RNC_PSESM  ;  Q4ZPE1, RNC_PSEU2  ;  Q4FUV6, RNC_PSYA2  ;
DR   A1SSM8, RNC_PSYIN  ;  Q1LKN1, RNC_RALME  ;  B2U981, RNC_RALPJ  ;
DR   Q8Y0I1, RNC_RALSO  ;  B3PUN8, RNC_RHIE6  ;  Q2KAE3, RNC_RHIEC  ;
DR   Q1MJ54, RNC_RHIL3  ;  Q985A6, RNC_RHILO  ;  B5ZW73, RNC_RHILW  ;
DR   Q92R47, RNC_RHIME  ;  C3M8S4, RNC_RHISN  ;  Q7UGZ7, RNC_RHOBA  ;
DR   Q52698, RNC_RHOCA  ;  Q21XN1, RNC_RHOFD  ;  Q6N6C1, RNC_RHOPA  ;
DR   A3PGF8, RNC_RHOS1  ;  Q3J5W1, RNC_RHOS4  ;  A4WVP5, RNC_RHOS5  ;
DR   B9KSA7, RNC_RHOSK  ;  C3PMF3, RNC_RICAE  ;  A8GM79, RNC_RICAH  ;
DR   A8GYE2, RNC_RICB8  ;  Q1RHA2, RNC_RICBR  ;  A8EXI3, RNC_RICCK  ;
DR   Q92JB0, RNC_RICCN  ;  Q4UKA8, RNC_RICFE  ;  A8F0M2, RNC_RICM5  ;
DR   Q9ZE31, RNC_RICPR  ;  C4K1R3, RNC_RICPU  ;  B0BW84, RNC_RICRO  ;
DR   A8GQT8, RNC_RICRS  ;  Q68XY5, RNC_RICTY  ;  A7NGC5, RNC_ROSCS  ;
DR   Q16AI6, RNC_ROSDO  ;  A5V230, RNC_ROSS1  ;  Q57LD0, RNC_SALCH  ;
DR   B5QTU8, RNC_SALEP  ;  B5RD49, RNC_SALG2  ;  Q5PIG5, RNC_SALPA  ;
DR   B5BAT0, RNC_SALPK  ;  Q8Z4K4, RNC_SALTI  ;  Q56056, RNC_SALTY  ;
DR   A8GI25, RNC_SERP5  ;  A1S3Y1, RNC_SHEAM  ;  B8EBQ2, RNC_SHEB2  ;
DR   A3D1V6, RNC_SHEB5  ;  A6WKQ7, RNC_SHEB8  ;  A9L5N6, RNC_SHEB9  ;
DR   Q12KI1, RNC_SHEDO  ;  Q07YZ6, RNC_SHEFN  ;  B0TIV7, RNC_SHEHH  ;
DR   A3QBS7, RNC_SHELP  ;  Q8EH81, RNC_SHEON  ;  A8H1C7, RNC_SHEPA  ;
DR   A4Y4K4, RNC_SHEPC  ;  B8CQJ5, RNC_SHEPW  ;  A0KZN2, RNC_SHESA  ;
DR   A8FSD6, RNC_SHESH  ;  Q0HG98, RNC_SHESM  ;  Q0HSJ1, RNC_SHESR  ;
DR   A1RMC7, RNC_SHESW  ;  B1KI57, RNC_SHEWM  ;  B2TXY0, RNC_SHIB3  ;
DR   Q31XS0, RNC_SHIBS  ;  Q32CV4, RNC_SHIDS  ;  Q0T1T8, RNC_SHIF8  ;
DR   P0A7Y3, RNC_SHIFL  ;  Q3YYU9, RNC_SHISS  ;  Q5LNK5, RNC_SILPO  ;
DR   A6U7A8, RNC_SINMW  ;  Q2NS13, RNC_SODGM  ;  Q027L3, RNC_SOLUE  ;
DR   Q1GTU3, RNC_SPHAL  ;  Q53844, RNC_SPICI  ;  A7X1J9, RNC_STAA1  ;
DR   A6U152, RNC_STAA2  ;  Q2FHK5, RNC_STAA3  ;  Q2FZ50, RNC_STAA8  ;
DR   A5ISB8, RNC_STAA9  ;  Q2YXI3, RNC_STAAB  ;  Q5HGJ9, RNC_STAAC  ;
DR   A6QGD3, RNC_STAAE  ;  Q931T1, RNC_STAAM  ;  P66668, RNC_STAAN  ;
DR   Q6GHK2, RNC_STAAR  ;  Q6G9Y0, RNC_STAAS  ;  A8Z3R9, RNC_STAAT  ;
DR   P66669, RNC_STAAW  ;  B9DPJ2, RNC_STACT  ;  Q5HPV8, RNC_STAEQ  ;
DR   Q8CPI1, RNC_STAES  ;  Q4L5T5, RNC_STAHJ  ;  Q49X17, RNC_STAS1  ;
DR   Q3K1Y2, RNC_STRA1  ;  Q8E680, RNC_STRA3  ;  Q8E0K7, RNC_STRA5  ;
DR   Q82JT9, RNC_STRAW  ;  Q9ZBQ7, RNC_STRCO  ;  C0M8Y3, RNC_STRE4  ;
DR   A8AWC2, RNC_STRGC  ;  Q8DT66, RNC_STRMU  ;  P66670, RNC_STRP1  ;
DR   Q04K72, RNC_STRP2  ;  P0DF14, RNC_STRP3  ;  B5E4Y2, RNC_STRP4  ;
DR   Q5XDA6, RNC_STRP6  ;  C1C7M6, RNC_STRP7  ;  P66672, RNC_STRP8  ;
DR   Q1JCZ9, RNC_STRPB  ;  Q1JMX4, RNC_STRPC  ;  Q1JI19, RNC_STRPD  ;
DR   Q1J7V3, RNC_STRPF  ;  A2RFW8, RNC_STRPG  ;  B1IC43, RNC_STRPI  ;
DR   B8ZJR8, RNC_STRPJ  ;  Q48UR6, RNC_STRPM  ;  Q97QG6, RNC_STRPN  ;
DR   P0DF15, RNC_STRPQ  ;  B2IPN5, RNC_STRPS  ;  B5XKB7, RNC_STRPZ  ;
DR   Q8DPJ8, RNC_STRR6  ;  C0MCR4, RNC_STRS7  ;  A3CP46, RNC_STRSV  ;
DR   Q5LZ68, RNC_STRT1  ;  Q5M3S3, RNC_STRT2  ;  Q03K17, RNC_STRTD  ;
DR   B9DRH1, RNC_STRU0  ;  C1CEK4, RNC_STRZJ  ;  C1CKY7, RNC_STRZP  ;
DR   C1CR56, RNC_STRZT  ;  A6QCJ0, RNC_SULNB  ;  Q67PF5, RNC_SYMTH  ;
DR   A0LGM1, RNC_SYNFM  ;  Q0AYW0, RNC_SYNWW  ;  Q47S78, RNC_THEFY  ;
DR   A8F397, RNC_THELT  ;  Q9X0I6, RNC_THEMA  ;  B9K9K8, RNC_THENN  ;
DR   A5IN74, RNC_THEP1  ;  B1LCY9, RNC_THESQ  ;  Q8R9W3, RNC_THETN  ;
DR   Q3SH50, RNC_THIDA  ;  Q73NX5, RNC_TREDE  ;  O83787, RNC_TREPA  ;
DR   B2S448, RNC_TREPS  ;  Q83I82, RNC_TROW8  ;  Q83FY2, RNC_TROWT  ;
DR   Q9PQT8, RNC_UREPA  ;  C5CSF5, RNC_VARPS  ;  A1WMW1, RNC_VEREI  ;
DR   A5F5H8, RNC_VIBC3  ;  Q9KPB2, RNC_VIBCH  ;  C3LR04, RNC_VIBCM  ;
DR   Q5E314, RNC_VIBF1  ;  A7MZA8, RNC_VIBHB  ;  Q87LN9, RNC_VIBPA  ;
DR   B7VK79, RNC_VIBSL  ;  Q8DC76, RNC_VIBVU  ;  Q7MHN8, RNC_VIBVY  ;
DR   Q8D305, RNC_WIGBR  ;  Q73FT3, RNC_WOLPM  ;  B3CMS0, RNC_WOLPP  ;
DR   Q7M840, RNC_WOLSU  ;  Q5GTI3, RNC_WOLTR  ;  C0R4Q8, RNC_WOLWR  ;
DR   Q8PMV0, RNC_XANAC  ;  Q3BVV6, RNC_XANC5  ;  Q4USF7, RNC_XANC8  ;
DR   Q8PB52, RNC_XANCP  ;  Q5H1R2, RNC_XANOR  ;  B2I604, RNC_XYLF2  ;
DR   Q9PB98, RNC_XYLFA  ;  B0U3D8, RNC_XYLFM  ;  Q87C06, RNC_XYLFT  ;
DR   A1JKK3, RNC_YERE8  ;  A7FFT9, RNC_YERP3  ;  Q1C555, RNC_YERPA  ;
DR   Q8ZD72, RNC_YERPE  ;  A9R402, RNC_YERPG  ;  Q1CKE4, RNC_YERPN  ;
DR   A4TKX8, RNC_YERPP  ;  Q667V1, RNC_YERPS  ;  Q9Z5U2, RNC_ZYMMO  ;
DR   Q02555, RNT1_YEAST ;
//
ID   3.1.26.4
DE   Ribonuclease H.
AN   Endoribonuclease H.
AN   RNase H.
CA   Endonucleolytic cleavage to 5'-phosphomonoester.
CC   -!- Acts on RNA-DNA hybrids.
PR   PROSITE; PDOC50879;
DR   Q64898, DPOL_ASHV  ;  P03162, DPOL_DHBV1 ;  P0C691, DPOL_DHBV3 ;
DR   Q66403, DPOL_DHBVQ ;  P28858, DPOL_EHV1B ;  Q6S6P1, DPOL_EHV1V ;
DR   Q9DKT8, DPOL_ELHVK ;  Q9E6N9, DPOL_GAHVM ;  P03161, DPOL_GSHV  ;
DR   P03158, DPOL_HBVA2 ;  P03159, DPOL_HBVA3 ;  P17100, DPOL_HBVA4 ;
DR   Q02314, DPOL_HBVA5 ;  Q91C36, DPOL_HBVA6 ;  O91533, DPOL_HBVA7 ;
DR   Q4R1S7, DPOL_HBVA8 ;  Q4R1R9, DPOL_HBVA9 ;  P17394, DPOL_HBVB1 ;
DR   P17393, DPOL_HBVB2 ;  Q9QAB8, DPOL_HBVB3 ;  P17395, DPOL_HBVB4 ;
DR   Q9PX62, DPOL_HBVB5 ;  Q67925, DPOL_HBVB6 ;  Q9QBF1, DPOL_HBVB7 ;
DR   P0C676, DPOL_HBVB8 ;  Q9E6S5, DPOL_HBVC0 ;  P0C688, DPOL_HBVC1 ;
DR   Q9YZR5, DPOL_HBVC2 ;  P12933, DPOL_HBVC3 ;  P31870, DPOL_HBVC4 ;
DR   P03157, DPOL_HBVC5 ;  Q913A7, DPOL_HBVC7 ;  Q81165, DPOL_HBVC8 ;
DR   P0C690, DPOL_HBVC9 ;  Q69028, DPOL_HBVCJ ;  P12900, DPOL_HBVCP ;
DR   P03155, DPOL_HBVD1 ;  P24024, DPOL_HBVD2 ;  P03156, DPOL_HBVD3 ;
DR   Q9QMI1, DPOL_HBVD4 ;  P0C679, DPOL_HBVD5 ;  Q67878, DPOL_HBVD6 ;
DR   O56655, DPOL_HBVD7 ;  Q69602, DPOL_HBVE1 ;  Q80IU7, DPOL_HBVE2 ;
DR   Q9QAW8, DPOL_HBVE3 ;  Q80IU4, DPOL_HBVE4 ;  Q05486, DPOL_HBVF1 ;
DR   Q8JMY4, DPOL_HBVF2 ;  Q99HS4, DPOL_HBVF3 ;  Q99HR5, DPOL_HBVF4 ;
DR   Q69605, DPOL_HBVF6 ;  Q8QZQ2, DPOL_HBVG2 ;  Q9IBI4, DPOL_HBVG3 ;
DR   P87744, DPOL_HBVGB ;  Q9YPV8, DPOL_HBVGO ;  Q8JMY7, DPOL_HBVH1 ;
DR   Q8JN08, DPOL_HBVH2 ;  Q8JMZ7, DPOL_HBVH3 ;  Q9J5S2, DPOL_HBVOR ;
DR   P13846, DPOL_HHBV  ;  P04293, DPOL_HHV11 ;  P07917, DPOL_HHV1A ;
DR   P04292, DPOL_HHV1K ;  P09854, DPOL_HHV1S ;  P07918, DPOL_HHV21 ;
DR   P89453, DPOL_HHV2H ;  P17192, DPOL_HPBDB ;  P30028, DPOL_HPBDC ;
DR   P17193, DPOL_HPBDW ;  Q6UDK1, DPOL_PSHV1 ;  P09252, DPOL_VZVD  ;
DR   Q4JQU7, DPOL_VZVO  ;  P03160, DPOL_WHV1  ;  P06275, DPOL_WHV2  ;
DR   P12899, DPOL_WHV3  ;  P12898, DPOL_WHV4  ;  P17396, DPOL_WHV5  ;
DR   P11292, DPOL_WHV6  ;  O71304, DPOL_WMHBV ;  P10266, POK10_HUMAN;
DR   P63135, POK12_HUMAN;  P63136, POK17_HUMAN;  Q9UQG0, POK20_HUMAN;
DR   Q9BXR3, POK2_HUMAN ;  Q9WJR5, POK3_HUMAN ;  P63128, POK4_HUMAN ;
DR   P63132, POK5_HUMAN ;  P63133, POK6_HUMAN ;  Q9QC07, POK7_HUMAN ;
DR   Q7SQ98, POL_ALV    ;  P03360, POL_AVIRE  ;  P10272, POL_BAEVM  ;
DR   P25059, POL_BLVAU  ;  P03361, POL_BLVJ   ;  P19199, POL_COYMV  ;
DR   Q89703, POL_CSVMV  ;  P31792, POL_FENV1  ;  O93209, POL_FFV    ;
DR   P10273, POL_FLV    ;  P14350, POL_FOAMV  ;  P21414, POL_GALV   ;
DR   P03362, POL_HTL1A  ;  P14078, POL_HTL1C  ;  P0C211, POL_HTL1L  ;
DR   Q0R5R2, POL_HTL32  ;  Q4U0X6, POL_HTL3P  ;  P03363, POL_HTLV2  ;
DR   P04026, POL_IPHA   ;  P11368, POL_IPMA   ;  P12894, POL_IPMAI  ;
DR   P31623, POL_JSRV   ;  Q9TTC1, POL_KORV   ;  P03356, POL_MLVAV  ;
DR   P26810, POL_MLVF5  ;  P26809, POL_MLVFF  ;  P26808, POL_MLVFP  ;
DR   P03355, POL_MLVMS  ;  P11227, POL_MLVRD  ;  P31795, POL_MLVRK  ;
DR   P03365, POL_MMTVB  ;  P11283, POL_MMTVC  ;  P07572, POL_MPMV   ;
DR   P03354, POL_RSVP   ;  Q04095, POL_RSVSA  ;  O92956, POL_RSVSB  ;
DR   P27502, POL_RTBVP  ;  P23074, POL_SFV1   ;  P27401, POL_SFV3L  ;
DR   Q87040, POL_SFVCP  ;  P03364, POL_SMRVH  ;  P04025, POL_SRV1   ;
DR   P51517, POL_SRV2   ;  O92815, POL_WDSV   ;  P03359, POL_WMSV   ;
DR   Q2F7J3, POL_XMRV3  ;  Q2F7J0, POL_XMRV4  ;  A1Z651, POL_XMRV6  ;
DR   Q9KEI9, RNH1_BACHD ;  Q07762, RNH1_CRIFA ;  O60930, RNH1_HUMAN ;
DR   O70338, RNH1_MOUSE ;  Q5BK46, RNH1_RAT   ;  Q9UST8, RNH1_SCHPO ;
DR   Q04740, RNH1_YEAST ;  A2SMZ3, RNH21_METPP;  Q67PD4, RNH21_SYMTH;
DR   A2SH85, RNH22_METPP;  Q67MS9, RNH22_SYMTH;  Q9SEZ6, RNH2A_ARATH;
DR   Q2TBT5, RNH2A_BOVIN;  Q9U6P6, RNH2A_CAEEL;  Q54D13, RNH2A_DICDI;
DR   Q9VPP5, RNH2A_DROME;  O75792, RNH2A_HUMAN;  Q9CWY8, RNH2A_MOUSE;
DR   Q9P5X8, RNH2A_NEUCR;  Q5U209, RNH2A_RAT  ;  Q10236, RNH2A_SCHPO;
DR   P53942, RNH2A_YEAST;  B0CAM1, RNH2_ACAM1 ;  A9NF30, RNH2_ACHLI ;
DR   A1TN83, RNH2_ACIAC ;  Q6FCT7, RNH2_ACIAD ;  Q1IMM1, RNH2_ACIBL ;
DR   A0LV66, RNH2_ACIC1 ;  A5FW78, RNH2_ACICJ ;  B9MGN1, RNH2_ACIET ;
DR   A1W904, RNH2_ACISJ ;  A3MYK1, RNH2_ACTP2 ;  B3GZX1, RNH2_ACTP7 ;
DR   B0BS34, RNH2_ACTPJ ;  A6VQJ4, RNH2_ACTSZ ;  A0KHH7, RNH2_AERHH ;
DR   Q9YET5, RNH2_AERPE ;  A4SQG8, RNH2_AERS4 ;  Q8UHG2, RNH2_AGRT5 ;
DR   Q0VQE3, RNH2_ALCBS ;  Q0A7J3, RNH2_ALHEH ;  B6EJW6, RNH2_ALISL ;
DR   A6TRS3, RNH2_ALKMQ ;  A8MHC7, RNH2_ALKOO ;  B4RVJ6, RNH2_ALTMD ;
DR   Q2IMM4, RNH2_ANADE ;  A7H722, RNH2_ANADF ;  Q5PBG2, RNH2_ANAMM ;
DR   Q2GJ70, RNH2_ANAPZ ;  B9MQX2, RNH2_ANATD ;  Q3MDN0, RNH2_ANAVT ;
DR   B7GGD5, RNH2_ANOFW ;  O67768, RNH2_AQUAE ;  A8EVA1, RNH2_ARCB4 ;
DR   O29634, RNH2_ARCFU ;  Q5NZG1, RNH2_AROAE ;  A0JXT5, RNH2_ARTS2 ;
DR   A8I6E6, RNH2_AZOC5 ;  A1K6Q7, RNH2_AZOSB ;  C1DST2, RNH2_AZOVD ;
DR   A7Z4M6, RNH2_BACA2 ;  C3P5N8, RNH2_BACAA ;  C3L790, RNH2_BACAC ;
DR   A0RHL0, RNH2_BACAH ;  Q81WJ9, RNH2_BACAN ;  B7JJB6, RNH2_BACC0 ;
DR   Q732N3, RNH2_BACC1 ;  B7IUJ6, RNH2_BACC2 ;  C1EP61, RNH2_BACC3 ;
DR   B7HDW0, RNH2_BACC4 ;  B7HLH0, RNH2_BACC7 ;  A7GRG7, RNH2_BACCN ;
DR   B9IVC6, RNH2_BACCQ ;  Q819W9, RNH2_BACCR ;  Q636I9, RNH2_BACCZ ;
DR   Q5LIL2, RNH2_BACFN ;  Q64ZN7, RNH2_BACFR ;  Q9Z9S0, RNH2_BACHD ;
DR   Q6HEX8, RNH2_BACHK ;  Q65JP3, RNH2_BACLD ;  A8FD70, RNH2_BACP2 ;
DR   Q5WFP1, RNH2_BACSK ;  O31744, RNH2_BACSU ;  Q8A293, RNH2_BACTN ;
DR   A6L046, RNH2_BACV8 ;  A9VT75, RNH2_BACWK ;  A1URV4, RNH2_BARBK ;
DR   Q6G4E3, RNH2_BARHE ;  Q6G0E6, RNH2_BARQU ;  A9IQL1, RNH2_BART1 ;
DR   Q6MLA0, RNH2_BDEBA ;  Q7VRD2, RNH2_BLOFL ;  Q493B8, RNH2_BLOPB ;
DR   Q2L146, RNH2_BORA1 ;  Q0SPB8, RNH2_BORAP ;  Q7WJ80, RNH2_BORBR ;
DR   O51075, RNH2_BORBU ;  B7J0Y4, RNH2_BORBZ ;  B5RKU7, RNH2_BORDL ;
DR   Q662W7, RNH2_BORGA ;  B2S1N3, RNH2_BORHD ;  Q7WA46, RNH2_BORPA ;
DR   Q7VYB6, RNH2_BORPE ;  B5RQM7, RNH2_BORRA ;  Q89S84, RNH2_BRAJA ;
DR   A5EEC1, RNH2_BRASB ;  A4YPP8, RNH2_BRASO ;  Q2YMC3, RNH2_BRUA2 ;
DR   Q57EX6, RNH2_BRUAB ;  A9M8G2, RNH2_BRUC2 ;  C0RH97, RNH2_BRUMB ;
DR   P0A4D9, RNH2_BRUME ;  A5VNW6, RNH2_BRUO2 ;  B0CK74, RNH2_BRUSI ;
DR   P0A4E0, RNH2_BRUSU ;  B1YS60, RNH2_BURA4 ;  Q1BHG8, RNH2_BURCA ;
DR   B1JUD6, RNH2_BURCC ;  A0K8C9, RNH2_BURCH ;  B4ECL7, RNH2_BURCJ ;
DR   Q0BE29, RNH2_BURCM ;  A3MKS8, RNH2_BURM7 ;  A2SB87, RNH2_BURM9 ;
DR   Q62JD8, RNH2_BURMA ;  A1V554, RNH2_BURMS ;  A3NWL6, RNH2_BURP0 ;
DR   Q3JR43, RNH2_BURP1 ;  A3NAT3, RNH2_BURP6 ;  B2T5I0, RNH2_BURPP ;
DR   Q63T26, RNH2_BURPS ;  Q39F57, RNH2_BURS3 ;  Q2SWY4, RNH2_BURTA ;
DR   A4JF61, RNH2_BURVG ;  Q13XD0, RNH2_BURXL ;  A8MAH5, RNH2_CALMQ ;
DR   A4XLE8, RNH2_CALS8 ;  A7ZG16, RNH2_CAMC1 ;  A7H121, RNH2_CAMC5 ;
DR   A7I0I5, RNH2_CAMHC ;  A8FJH3, RNH2_CAMJ8 ;  A7H1A3, RNH2_CAMJD ;
DR   Q9PJA1, RNH2_CAMJE ;  A1VX88, RNH2_CAMJJ ;  Q5HXE7, RNH2_CAMJR ;
DR   Q3AC76, RNH2_CARHZ ;  B8GZ34, RNH2_CAUCN ;  P0CAW4, RNH2_CAUCR ;
DR   B0SZF7, RNH2_CAUSK ;  A0RV25, RNH2_CENSY ;  A9WIH1, RNH2_CHLAA ;
DR   Q5L5M0, RNH2_CHLAB ;  B8GBB1, RNH2_CHLAD ;  Q3AP34, RNH2_CHLCH ;
DR   Q822M7, RNH2_CHLCV ;  Q255A9, RNH2_CHLFF ;  Q9PL10, RNH2_CHLMU ;
DR   B3QQY0, RNH2_CHLP8 ;  A1BCI1, RNH2_CHLPD ;  Q9Z962, RNH2_CHLPN ;
DR   B9LAL2, RNH2_CHLSY ;  B0B9D6, RNH2_CHLT2 ;  B3QRP3, RNH2_CHLT3 ;
DR   Q3KMZ3, RNH2_CHLTA ;  B0BB15, RNH2_CHLTB ;  Q8KAA5, RNH2_CHLTE ;
DR   O84032, RNH2_CHLTR ;  Q1R019, RNH2_CHRSD ;  Q7NPS3, RNH2_CHRVO ;
DR   A8ALA5, RNH2_CITK8 ;  Q97I90, RNH2_CLOAB ;  A7FW05, RNH2_CLOB1 ;
DR   A6LSN4, RNH2_CLOB8 ;  A5I4L9, RNH2_CLOBH ;  B1II72, RNH2_CLOBK ;
DR   A7GG29, RNH2_CLOBL ;  B1KWN1, RNH2_CLOBM ;  B8I7T9, RNH2_CLOCE ;
DR   Q18BC9, RNH2_CLOD6 ;  A5N820, RNH2_CLOK5 ;  A0Q0X7, RNH2_CLONN ;
DR   Q0TPP7, RNH2_CLOP1 ;  Q8XJQ0, RNH2_CLOPE ;  A9KLL7, RNH2_CLOPH ;
DR   Q0SSB4, RNH2_CLOPS ;  Q895L8, RNH2_CLOTE ;  A3DDG7, RNH2_CLOTH ;
DR   Q485F4, RNH2_COLP3 ;  Q6NGJ8, RNH2_CORDI ;  Q8FP63, RNH2_COREF ;
DR   A4QF39, RNH2_CORGB ;  Q8NNZ4, RNH2_CORGL ;  Q4JV11, RNH2_CORJK ;
DR   B6J7Z2, RNH2_COXB1 ;  B6IZE4, RNH2_COXB2 ;  A9KGD3, RNH2_COXBN ;
DR   A9N8L5, RNH2_COXBR ;  Q83BZ8, RNH2_COXBU ;  Q0KA30, RNH2_CUPNH ;
DR   Q470F1, RNH2_CUPPJ ;  Q11R91, RNH2_CYTH3 ;  Q47F78, RNH2_DECAR ;
DR   Q3Z8D7, RNH2_DEHE1 ;  A5FR86, RNH2_DEHSB ;  Q3ZXD6, RNH2_DEHSC ;
DR   A9BML8, RNH2_DELAS ;  Q313K1, RNH2_DESDG ;  B8FRK8, RNH2_DESHD ;
DR   Q24UB4, RNH2_DESHY ;  Q6AJE5, RNH2_DESPS ;  A4J661, RNH2_DESRM ;
DR   Q72DU5, RNH2_DESVH ;  A1VFE7, RNH2_DESVV ;  A5EV63, RNH2_DICNV ;
DR   A8LJU6, RNH2_DINSH ;  A7ZHS3, RNH2_ECO24 ;  B7UJ84, RNH2_ECO27 ;
DR   B7MBG4, RNH2_ECO45 ;  B7LGP5, RNH2_ECO55 ;  Q8X8X6, RNH2_ECO57 ;
DR   B5Z0G2, RNH2_ECO5E ;  B7NIE5, RNH2_ECO7I ;  B7MP43, RNH2_ECO81 ;
DR   B7M1Y6, RNH2_ECO8A ;  C4ZRS5, RNH2_ECOBW ;  B1XD52, RNH2_ECODH ;
DR   A7ZWC9, RNH2_ECOHS ;  A1A7M7, RNH2_ECOK1 ;  Q0TLF0, RNH2_ECOL5 ;
DR   Q8FL06, RNH2_ECOL6 ;  B1IQF8, RNH2_ECOLC ;  P10442, RNH2_ECOLI ;
DR   B7N850, RNH2_ECOLU ;  B6HZF7, RNH2_ECOSE ;  B1LGY5, RNH2_ECOSM ;
DR   Q1RG06, RNH2_ECOUT ;  C5B7S2, RNH2_EDWI9 ;  Q3YST1, RNH2_EHRCJ ;
DR   Q2GFP8, RNH2_EHRCR ;  Q5FFD4, RNH2_EHRRG ;  Q5HC01, RNH2_EHRRW ;
DR   A4W6S8, RNH2_ENT38 ;  Q834J7, RNH2_ENTFA ;  A7MI15, RNH2_ENTS8 ;
DR   Q6D8C9, RNH2_ERWCT ;  B2VHY0, RNH2_ERWT9 ;  Q2NCP5, RNH2_ERYLH ;
DR   B7LW62, RNH2_ESCF3 ;  A5FIL7, RNH2_FLAJ1 ;  A6GYW0, RNH2_FLAPJ ;
DR   Q0RDP7, RNH2_FRAAA ;  B0TYD6, RNH2_FRAP2 ;  Q2J702, RNH2_FRASC ;
DR   A8L6C6, RNH2_FRASN ;  Q14GW0, RNH2_FRAT1 ;  A7NCM0, RNH2_FRATF ;
DR   Q2A337, RNH2_FRATH ;  B2SGW7, RNH2_FRATM ;  A0Q7F9, RNH2_FRATN ;
DR   Q0BLL3, RNH2_FRATO ;  Q5NFF8, RNH2_FRATT ;  A4IX19, RNH2_FRATW ;
DR   Q8RDX3, RNH2_FUSNN ;  B5EBC6, RNH2_GEOBB ;  Q5L0P0, RNH2_GEOKA ;
DR   Q39RP1, RNH2_GEOMG ;  B9M597, RNH2_GEOSF ;  Q74FG0, RNH2_GEOSL ;
DR   C6E5I4, RNH2_GEOSM ;  C5D8U9, RNH2_GEOSW ;  A4IM80, RNH2_GEOTN ;
DR   A5G7Z2, RNH2_GEOUR ;  A9H3E2, RNH2_GLUDA ;  Q5FU18, RNH2_GLUOX ;
DR   Q0BQZ6, RNH2_GRABC ;  A0M5H5, RNH2_GRAFK ;  Q7VMF2, RNH2_HAEDU ;
DR   Q4QLM7, RNH2_HAEI8 ;  A5UD45, RNH2_HAEIE ;  A5UII7, RNH2_HAEIG ;
DR   P43808, RNH2_HAEIN ;  Q0I4M6, RNH2_HAES1 ;  B0UW63, RNH2_HAES2 ;
DR   Q2SBR2, RNH2_HAHCH ;  A1WX09, RNH2_HALHL ;  Q5UXT4, RNH2_HALMA ;
DR   B0R6T4, RNH2_HALS3 ;  Q9HNR3, RNH2_HALSA ;  C4K435, RNH2_HAMD5 ;
DR   Q17ZE2, RNH2_HELAH ;  B6JNG1, RNH2_HELP2 ;  B5Z8X1, RNH2_HELPG ;
DR   Q1CRT7, RNH2_HELPH ;  Q9ZJR1, RNH2_HELPJ ;  B2UV86, RNH2_HELPS ;
DR   P56121, RNH2_HELPY ;  A9B6H3, RNH2_HERA2 ;  A4G4T5, RNH2_HERAR ;
DR   A2BL34, RNH2_HYPBU ;  Q0BYK9, RNH2_HYPNA ;  Q5QZK7, RNH2_IDILO ;
DR   A6SZN7, RNH2_JANMA ;  Q28VF4, RNH2_JANSC ;  A6W7V4, RNH2_KINRD ;
DR   B5Y1I8, RNH2_KLEP3 ;  A6T4Y5, RNH2_KLEP7 ;  Q5FKE4, RNH2_LACAC ;
DR   Q03S83, RNH2_LACBA ;  Q039E6, RNH2_LACC3 ;  B3WEA2, RNH2_LACCB ;
DR   Q1G9U8, RNH2_LACDA ;  Q049Z9, RNH2_LACDB ;  B2GC51, RNH2_LACF3 ;
DR   Q043R9, RNH2_LACGA ;  A8YV45, RNH2_LACH4 ;  Q74JK1, RNH2_LACJO ;
DR   Q9CG17, RNH2_LACLA ;  O30415, RNH2_LACLM ;  Q02YP2, RNH2_LACLS ;
DR   Q88W20, RNH2_LACPL ;  A5VJL7, RNH2_LACRD ;  B2G731, RNH2_LACRJ ;
DR   Q1WU07, RNH2_LACS1 ;  Q38WY6, RNH2_LACSS ;  C1D4C1, RNH2_LARHH ;
DR   Q1MRU8, RNH2_LAWIP ;  Q5X5J3, RNH2_LEGPA ;  A5IBL5, RNH2_LEGPC ;
DR   Q5ZVR7, RNH2_LEGPH ;  Q5WWX5, RNH2_LEGPL ;  B1MZ17, RNH2_LEUCK ;
DR   Q03Y48, RNH2_LEUMM ;  Q92C79, RNH2_LISIN ;  C1L2I1, RNH2_LISMC ;
DR   Q720E8, RNH2_LISMF ;  B8DHN2, RNH2_LISMH ;  Q8Y7K4, RNH2_LISMO ;
DR   A0AI76, RNH2_LISW6 ;  B9EBC6, RNH2_MACCJ ;  Q50412, RNH2_MAGSA ;
DR   A0L4Z0, RNH2_MAGSM ;  Q65VI0, RNH2_MANSM ;  A1U3P0, RNH2_MARAV ;
DR   Q0AMK3, RNH2_MARMM ;  A6VUT6, RNH2_MARMS ;  Q11KH2, RNH2_MESSB ;
DR   A6UUM1, RNH2_META3 ;  Q8TPF4, RNH2_METAC ;  A7I9P7, RNH2_METB6 ;
DR   Q468N6, RNH2_METBF ;  Q12YN9, RNH2_METBU ;  Q604U3, RNH2_METCA ;
DR   Q1H153, RNH2_METFK ;  Q2FP80, RNH2_METHJ ;  Q57599, RNH2_METJA ;
DR   Q8TYV5, RNH2_METKA ;  A2STJ6, RNH2_METLZ ;  A4FWE5, RNH2_METM5 ;
DR   A9A9T9, RNH2_METM6 ;  A6VGW0, RNH2_METM7 ;  Q8PTA3, RNH2_METMA ;
DR   Q6LXH7, RNH2_METMP ;  A5ULV6, RNH2_METS3 ;  Q2NEI6, RNH2_METST ;
DR   O27102, RNH2_METTH ;  A0B796, RNH2_METTP ;  A6UQ18, RNH2_METVS ;
DR   B0JV09, RNH2_MICAN ;  Q2RJU8, RNH2_MOOTA ;  A0QJ41, RNH2_MYCA1 ;
DR   B1MDH9, RNH2_MYCA9 ;  Q7TXM7, RNH2_MYCBO ;  A1KMP6, RNH2_MYCBP ;
DR   C1AG17, RNH2_MYCBT ;  Q2SRV0, RNH2_MYCCT ;  A4TE84, RNH2_MYCGI ;
DR   B8ZRW3, RNH2_MYCLB ;  O33022, RNH2_MYCLE ;  B2HJL9, RNH2_MYCMM ;
DR   Q6MTH8, RNH2_MYCMS ;  Q73VP3, RNH2_MYCPA ;  A0QV44, RNH2_MYCS2 ;
DR   A3PXW3, RNH2_MYCSJ ;  A1UEF9, RNH2_MYCSK ;  Q1BAK3, RNH2_MYCSS ;
DR   A5U6Q7, RNH2_MYCTA ;  Q10793, RNH2_MYCTU ;  A0PQ70, RNH2_MYCUA ;
DR   A1T759, RNH2_MYCVP ;  Q1D980, RNH2_MYXXD ;  Q74MH3, RNH2_NANEQ ;
DR   Q3IRF6, RNH2_NATPD ;  B2A2P0, RNH2_NATTJ ;  Q5F5X9, RNH2_NEIG1 ;
DR   A9M3R5, RNH2_NEIM0 ;  Q9JX40, RNH2_NEIMA ;  Q9K1G1, RNH2_NEIMB ;
DR   A1KRM4, RNH2_NEIMF ;  Q2GD69, RNH2_NEOSM ;  Q0AEI5, RNH2_NITEC ;
DR   Q82U06, RNH2_NITEU ;  Q1QIJ1, RNH2_NITHX ;  Q2YB96, RNH2_NITMU ;
DR   Q3J9L3, RNH2_NITOC ;  Q3SPE0, RNH2_NITWN ;  Q5YS47, RNH2_NOCFA ;
DR   A1SLS0, RNH2_NOCSJ ;  Q8YP68, RNH2_NOSS1 ;  Q2G794, RNH2_NOVAD ;
DR   Q8EQZ4, RNH2_OCEIH ;  A6WW84, RNH2_OCHA4 ;  A5CDI4, RNH2_ORITB ;
DR   B3CUN5, RNH2_ORITI ;  A6LHT2, RNH2_PARD8 ;  A1B3V0, RNH2_PARDP ;
DR   A7HQZ3, RNH2_PARL1 ;  Q6MDG7, RNH2_PARUW ;  P57986, RNH2_PASMU ;
DR   C6DAJ7, RNH2_PECCP ;  Q03FJ5, RNH2_PEDPA ;  Q3A2F0, RNH2_PELCD ;
DR   Q3B6X8, RNH2_PELLD ;  B4SAK8, RNH2_PELPB ;  A1AMZ7, RNH2_PELPD ;
DR   A5D1I3, RNH2_PELTS ;  Q4FPF7, RNH2_PELUB ;  Q7N8N3, RNH2_PHOLL ;
DR   Q6LN38, RNH2_PHOPR ;  Q6KZK4, RNH2_PICTO ;  A1VN54, RNH2_POLNA ;
DR   B1XTV7, RNH2_POLNS ;  Q12A45, RNH2_POLSJ ;  A4SYT7, RNH2_POLSQ ;
DR   B2RIU1, RNH2_PORG3 ;  Q51832, RNH2_PORGI ;  Q6A7T3, RNH2_PROAC ;
DR   A3PEZ1, RNH2_PROM0 ;  A2C4T9, RNH2_PROM1 ;  A8G702, RNH2_PROM2 ;
DR   A2CC94, RNH2_PROM3 ;  A2BYM8, RNH2_PROM5 ;  Q318P1, RNH2_PROM9 ;
DR   Q7VA11, RNH2_PROMA ;  B4F256, RNH2_PROMH ;  Q7V4Z5, RNH2_PROMM ;
DR   Q7UZZ2, RNH2_PROMP ;  A2BT77, RNH2_PROMS ;  Q46IX0, RNH2_PROMT ;
DR   A4SC35, RNH2_PROVI ;  Q48F73, RNH2_PSE14 ;  Q15WE9, RNH2_PSEA6 ;
DR   A6V1E6, RNH2_PSEA7 ;  B7V7U6, RNH2_PSEA8 ;  Q02RB4, RNH2_PSEAB ;
DR   Q9HXY9, RNH2_PSEAE ;  Q1I640, RNH2_PSEE4 ;  Q4KHG2, RNH2_PSEF5 ;
DR   Q3IIW9, RNH2_PSEHT ;  A4XWS7, RNH2_PSEMY ;  A5W836, RNH2_PSEP1 ;
DR   Q3KH98, RNH2_PSEPF ;  B0KSB3, RNH2_PSEPG ;  Q88MG6, RNH2_PSEPK ;
DR   B1JBP6, RNH2_PSEPW ;  Q886M9, RNH2_PSESM ;  Q4ZWR4, RNH2_PSEU2 ;
DR   A4VJT5, RNH2_PSEU5 ;  Q4FT93, RNH2_PSYA2 ;  Q1QAL9, RNH2_PSYCK ;
DR   A1SYU9, RNH2_PSYIN ;  A5WDY2, RNH2_PSYWF ;  Q9V1A9, RNH2_PYRAB ;
DR   Q8ZXL6, RNH2_PYRAE ;  A4WHQ7, RNH2_PYRAR ;  Q8U036, RNH2_PYRFU ;
DR   O59351, RNH2_PYRHO ;  A1RU36, RNH2_PYRIL ;  O74035, RNH2_PYRKO ;
DR   Q1LNE4, RNH2_RALME ;  B2UBB5, RNH2_RALPJ ;  Q8XZH7, RNH2_RALSO ;
DR   B3PRG0, RNH2_RHIE6 ;  Q2KBV7, RNH2_RHIEC ;  Q1MKS7, RNH2_RHIL3 ;
DR   Q986D0, RNH2_RHILO ;  B5ZS20, RNH2_RHILW ;  Q92RM4, RNH2_RHIME ;
DR   C3MHC0, RNH2_RHISN ;  C0ZXT2, RNH2_RHOE4 ;  Q21WX6, RNH2_RHOFD ;
DR   C1B2S6, RNH2_RHOOB ;  Q2J169, RNH2_RHOP2 ;  Q07I86, RNH2_RHOP5 ;
DR   Q6NAZ6, RNH2_RHOPA ;  Q20YA2, RNH2_RHOPB ;  Q13BU3, RNH2_RHOPS ;
DR   B3QHK8, RNH2_RHOPT ;  Q2RPE1, RNH2_RHORT ;  A3PFX4, RNH2_RHOS1 ;
DR   Q3J6H3, RNH2_RHOS4 ;  A4WNL5, RNH2_RHOS5 ;  B9KRA6, RNH2_RHOSK ;
DR   Q0S2B9, RNH2_RHOSR ;  C3PMP4, RNH2_RICAE ;  A8GMJ0, RNH2_RICAH ;
DR   A8GVS9, RNH2_RICB8 ;  Q1RJ72, RNH2_RICBR ;  A8EXS5, RNH2_RICCK ;
DR   Q92J05, RNH2_RICCN ;  Q4UKL5, RNH2_RICFE ;  A8F0V8, RNH2_RICM5 ;
DR   Q9ZDW3, RNH2_RICPR ;  B0BWJ9, RNH2_RICRO ;  A8GR51, RNH2_RICRS ;
DR   Q68XG6, RNH2_RICTY ;  A7NM86, RNH2_ROSCS ;  Q16DB9, RNH2_ROSDO ;
DR   A5UX01, RNH2_ROSS1 ;  Q21HI6, RNH2_SACD2 ;  A4FME5, RNH2_SACEN ;
DR   B5F8U4, RNH2_SALA4 ;  A8M684, RNH2_SALAI ;  A9MPH8, RNH2_SALAR ;
DR   Q57T25, RNH2_SALCH ;  B5FJ30, RNH2_SALDC ;  B5R422, RNH2_SALEP ;
DR   B5R5I6, RNH2_SALG2 ;  B4TK58, RNH2_SALHS ;  B4SV12, RNH2_SALNS ;
DR   Q5PD71, RNH2_SALPA ;  A9N0T3, RNH2_SALPB ;  C0Q6K6, RNH2_SALPC ;
DR   B5BAP0, RNH2_SALPK ;  Q2S009, RNH2_SALRD ;  B4TYE3, RNH2_SALSV ;
DR   P0A2C2, RNH2_SALTI ;  A4X4I2, RNH2_SALTO ;  P0A2C1, RNH2_SALTY ;
DR   A8GID2, RNH2_SERP5 ;  A1S4Q4, RNH2_SHEAM ;  B8E7Q2, RNH2_SHEB2 ;
DR   A3D2L9, RNH2_SHEB5 ;  A6WLC0, RNH2_SHEB8 ;  A9KUL9, RNH2_SHEB9 ;
DR   Q12NX3, RNH2_SHEDO ;  Q085C8, RNH2_SHEFN ;  B0TP69, RNH2_SHEHH ;
DR   A3QG89, RNH2_SHELP ;  Q8EGG1, RNH2_SHEON ;  A8H6K2, RNH2_SHEPA ;
DR   A4Y557, RNH2_SHEPC ;  B8CQ71, RNH2_SHEPW ;  A0KZ09, RNH2_SHESA ;
DR   A8FY28, RNH2_SHESH ;  Q0HGW9, RNH2_SHESM ;  Q0HT76, RNH2_SHESR ;
DR   A1RLL3, RNH2_SHESW ;  B1KNS9, RNH2_SHEWM ;  B2U326, RNH2_SHIB3 ;
DR   Q325V7, RNH2_SHIBS ;  Q32JS6, RNH2_SHIDS ;  Q0T826, RNH2_SHIF8 ;
DR   Q83MN1, RNH2_SHIFL ;  Q3Z5H5, RNH2_SHISS ;  Q5LMW0, RNH2_SILPO ;
DR   Q1GD84, RNH2_SILST ;  A6U6M8, RNH2_SINMW ;  Q2NRM1, RNH2_SODGM ;
DR   Q024M2, RNH2_SOLUE ;  Q1GUJ1, RNH2_SPHAL ;  A5VF46, RNH2_SPHWW ;
DR   A7X1L7, RNH2_STAA1 ;  A6U163, RNH2_STAA2 ;  Q2FHJ4, RNH2_STAA3 ;
DR   Q2FZ38, RNH2_STAA8 ;  A5ISC9, RNH2_STAA9 ;  Q2YXM2, RNH2_STAAB ;
DR   Q5HGI8, RNH2_STAAC ;  A6QGE4, RNH2_STAAE ;  P66675, RNH2_STAAM ;
DR   P66676, RNH2_STAAN ;  Q6GHJ1, RNH2_STAAR ;  Q6G9W9, RNH2_STAAS ;
DR   A8Z3S4, RNH2_STAAT ;  Q8NX02, RNH2_STAAW ;  B9DPH3, RNH2_STACT ;
DR   Q5HPU6, RNH2_STAEQ ;  Q8CPH6, RNH2_STAES ;  Q4L5U7, RNH2_STAHJ ;
DR   Q49X31, RNH2_STAS1 ;  Q3K175, RNH2_STRA1 ;  Q8E5I2, RNH2_STRA3 ;
DR   Q8DZT5, RNH2_STRA5 ;  Q82KF0, RNH2_STRAW ;  O69989, RNH2_STRCO ;
DR   B4U2W6, RNH2_STREM ;  A8AXH8, RNH2_STRGC ;  B1VXS2, RNH2_STRGG ;
DR   Q8DUE1, RNH2_STRMU ;  Q99ZM6, RNH2_STRP1 ;  Q04KF4, RNH2_STRP2 ;
DR   P0DF16, RNH2_STRP3 ;  B5E4Q2, RNH2_STRP4 ;  Q5XC49, RNH2_STRP6 ;
DR   C1C7C8, RNH2_STRP7 ;  Q8P109, RNH2_STRP8 ;  Q1JBP9, RNH2_STRPB ;
DR   Q1JLN1, RNH2_STRPC ;  Q1JGT2, RNH2_STRPD ;  Q1J6K1, RNH2_STRPF ;
DR   A2REG0, RNH2_STRPG ;  B1IBW1, RNH2_STRPI ;  B8ZQ37, RNH2_STRPJ ;
DR   Q48TJ0, RNH2_STRPM ;  Q97QP5, RNH2_STRPN ;  P0DF17, RNH2_STRPQ ;
DR   B2IPW8, RNH2_STRPS ;  B5XLK7, RNH2_STRPZ ;  Q8DPR3, RNH2_STRR6 ;
DR   A4W1C8, RNH2_STRS2 ;  A3CN38, RNH2_STRSV ;  A4VV23, RNH2_STRSY ;
DR   Q5M021, RNH2_STRT1 ;  Q5M4N6, RNH2_STRT2 ;  Q03KX7, RNH2_STRTD ;
DR   B9DS69, RNH2_STRU0 ;  C1CEC3, RNH2_STRZJ ;  C1CKQ7, RNH2_STRZP ;
DR   C1CRN4, RNH2_STRZT ;  Q4JA60, RNH2_SULAC ;  A6QCJ3, RNH2_SULNB ;
DR   Q97W56, RNH2_SULSO ;  B2V752, RNH2_SULSY ;  Q974Z3, RNH2_SULTO ;
DR   Q2LVU5, RNH2_SYNAS ;  Q31PW0, RNH2_SYNE7 ;  A0LMM5, RNH2_SYNFM ;
DR   Q2JW45, RNH2_SYNJA ;  Q2JKK9, RNH2_SYNJB ;  Q5N4B8, RNH2_SYNP6 ;
DR   A5GIN4, RNH2_SYNPW ;  Q7U4C6, RNH2_SYNPX ;  A5GW20, RNH2_SYNR3 ;
DR   Q0ID65, RNH2_SYNS3 ;  Q3AW47, RNH2_SYNS9 ;  Q3AMU2, RNH2_SYNSC ;
DR   Q0AWX1, RNH2_SYNWW ;  P72657, RNH2_SYNY3 ;  B7IF45, RNH2_THEAB ;
DR   P57673, RNH2_THEAC ;  Q8DL36, RNH2_THEEB ;  Q47MZ1, RNH2_THEFY ;
DR   A8F5M9, RNH2_THELT ;  A6LP91, RNH2_THEM4 ;  Q9X017, RNH2_THEMA ;
DR   B1YB67, RNH2_THENV ;  B6YVT5, RNH2_THEON ;  A5IIL8, RNH2_THEP1 ;
DR   A1RYM0, RNH2_THEPD ;  C6A1I4, RNH2_THESM ;  B1LC19, RNH2_THESQ ;
DR   Q72GR0, RNH2_THET2 ;  Q5SLU5, RNH2_THET8 ;  Q8R9X9, RNH2_THETN ;
DR   Q97CG6, RNH2_THEVO ;  Q31G56, RNH2_THICR ;  Q3SKM7, RNH2_THIDA ;
DR   B8GQ66, RNH2_THISH ;  Q73MG1, RNH2_TREDE ;  Q118Y6, RNH2_TRIEI ;
DR   Q0W5R8, RNH2_UNCMA ;  B1GZ18, RNH2_UNCTG ;  A1WHV6, RNH2_VEREI ;
DR   A5F626, RNH2_VIBC3 ;  P52021, RNH2_VIBCH ;  C3LQ18, RNH2_VIBCM ;
DR   Q5E3F3, RNH2_VIBF1 ;  B5F9W2, RNH2_VIBFM ;  A7MY01, RNH2_VIBHB ;
DR   Q87MF1, RNH2_VIBPA ;  B7VIQ4, RNH2_VIBSL ;  Q8DBE7, RNH2_VIBVU ;
DR   Q7MIH3, RNH2_VIBVY ;  Q73G60, RNH2_WOLPM ;  B3CM59, RNH2_WOLPP ;
DR   Q5GRZ4, RNH2_WOLTR ;  C0R4W4, RNH2_WOLWR ;  Q8PML9, RNH2_XANAC ;
DR   Q4USP6, RNH2_XANC8 ;  B0RW80, RNH2_XANCB ;  Q8PAW7, RNH2_XANCP ;
DR   Q2P4B9, RNH2_XANOM ;  Q5H1F4, RNH2_XANOR ;  A7IES2, RNH2_XANP2 ;
DR   B2I7N7, RNH2_XYLF2 ;  Q9PEI7, RNH2_XYLFA ;  B0U235, RNH2_XYLFM ;
DR   Q87EI6, RNH2_XYLFT ;  A1JP66, RNH2_YERE8 ;  A7FFI3, RNH2_YERP3 ;
DR   Q1CAM0, RNH2_YERPA ;  B2JZ20, RNH2_YERPB ;  Q8ZH54, RNH2_YERPE ;
DR   A9R382, RNH2_YERPG ;  Q1CFG1, RNH2_YERPN ;  A4TL77, RNH2_YERPP ;
DR   Q667K3, RNH2_YERPS ;  B1JQH4, RNH2_YERPY ;  Q5NNT2, RNH2_ZYMMO ;
DR   O67644, RNH3_AQUAE ;  A7Z7F1, RNH3_BACA2 ;  C3PAE4, RNH3_BACAA ;
DR   C3L8T2, RNH3_BACAC ;  Q81L36, RNH3_BACAN ;  Q72ZI6, RNH3_BACC1 ;
DR   C1ETZ4, RNH3_BACC3 ;  B7HRJ7, RNH3_BACC7 ;  Q817J0, RNH3_BACCR ;
DR   Q633N8, RNH3_BACCZ ;  Q6HCX2, RNH3_BACHK ;  Q65GD8, RNH3_BACLD ;
DR   A8FG15, RNH3_BACP2 ;  P94541, RNH3_BACSU ;  A9VJL6, RNH3_BACWK ;
DR   Q5L6I4, RNH3_CHLAB ;  Q823W2, RNH3_CHLCV ;  Q253Q7, RNH3_CHLFF ;
DR   Q9PL32, RNH3_CHLMU ;  Q9Z6J1, RNH3_CHLPN ;  B0B9B5, RNH3_CHLT2 ;
DR   Q3KN14, RNH3_CHLTA ;  B0BAZ4, RNH3_CHLTB ;  O84011, RNH3_CHLTR ;
DR   Q835V5, RNH3_ENTFA ;  B1YJY9, RNH3_EXIS2 ;  Q5KWF4, RNH3_GEOKA ;
DR   C5D5R2, RNH3_GEOSW ;  B2GB29, RNH3_LACF3 ;  Q9CDG3, RNH3_LACLA ;
DR   A2RP65, RNH3_LACLM ;  Q02VL7, RNH3_LACLS ;  B1MXB1, RNH3_LEUCK ;
DR   Q03VG4, RNH3_LEUMM ;  Q92CI0, RNH3_LISIN ;  C1L2D3, RNH3_LISMC ;
DR   Q720K1, RNH3_LISMF ;  Q8Y7P5, RNH3_LISMO ;  B1HW99, RNH3_LYSSC ;
DR   B9E764, RNH3_MACCJ ;  Q8EPH7, RNH3_OCEIH ;  Q6MDE6, RNH3_PARUW ;
DR   B3R0F3, RNH3_PHYMT ;  A7X163, RNH3_STAA1 ;  A6U0V7, RNH3_STAA2 ;
DR   Q2FHU1, RNH3_STAA3 ;  Q2FZD7, RNH3_STAA8 ;  A5IS26, RNH3_STAA9 ;
DR   Q5HGU4, RNH3_STAAC ;  A6QG41, RNH3_STAAE ;  Q99UW5, RNH3_STAAM ;
DR   Q7A647, RNH3_STAAN ;  Q6GHU5, RNH3_STAAR ;  Q6GA74, RNH3_STAAS ;
DR   Q8NX59, RNH3_STAAW ;  Q5HQ34, RNH3_STAEQ ;  Q8CPL8, RNH3_STAES ;
DR   Q4L5E5, RNH3_STAHJ ;  Q49WQ7, RNH3_STAS1 ;  Q3JZH3, RNH3_STRA1 ;
DR   Q8E3J2, RNH3_STRA3 ;  Q8DXX3, RNH3_STRA5 ;  A8AUW5, RNH3_STRGC ;
DR   Q8DSC8, RNH3_STRMU ;  P66677, RNH3_STRP1 ;  Q04M70, RNH3_STRP2 ;
DR   P0DF18, RNH3_STRP3 ;  B5E7E5, RNH3_STRP4 ;  Q5XA52, RNH3_STRP6 ;
DR   C1C5E1, RNH3_STRP7 ;  P66678, RNH3_STRP8 ;  Q1JA20, RNH3_STRPB ;
DR   Q1JK67, RNH3_STRPC ;  Q1JF63, RNH3_STRPD ;  Q1J513, RNH3_STRPF ;
DR   A2RCQ5, RNH3_STRPG ;  B1I9J8, RNH3_STRPI ;  B8ZLH1, RNH3_STRPJ ;
DR   Q48RJ8, RNH3_STRPM ;  O07874, RNH3_STRPN ;  P0DF19, RNH3_STRPQ ;
DR   B2ILU9, RNH3_STRPS ;  B5XI49, RNH3_STRPZ ;  P59660, RNH3_STRR6 ;
DR   Q5LY37, RNH3_STRT1 ;  Q5M2P2, RNH3_STRT2 ;  Q03IU1, RNH3_STRTD ;
DR   B9DVL0, RNH3_STRU0 ;  C1CCH0, RNH3_STRZJ ;  C1CIQ5, RNH3_STRZP ;
DR   C1CPR4, RNH3_STRZT ;  B1AJ36, RNH3_UREP2 ;  Q9PQ93, RNH3_UREPA ;
DR   P0C2F6, RNHX1_ARATH;  A1TQI7, RNH_ACIAC  ;  A5FZ26, RNH_ACICJ  ;
DR   B7J4E2, RNH_ACIF2  ;  B5EMD8, RNH_ACIF5  ;  A1W6Q8, RNH_ACISJ  ;
DR   A3MZE1, RNH_ACTP2  ;  A6VMP9, RNH_ACTSZ  ;  A0KIK4, RNH_AERHH  ;
DR   A4SPI4, RNH_AERS4  ;  Q8UHA7, RNH_AGRT5  ;  Q0VQ76, RNH_ALCBS  ;
DR   Q0A753, RNH_ALHEH  ;  B6EJV2, RNH_ALISL  ;  B8J731, RNH_ANAD2  ;
DR   Q2IJL8, RNH_ANADE  ;  A7HB50, RNH_ANADF  ;  Q5PBQ8, RNH_ANAMM  ;
DR   B4UMK8, RNH_ANASK  ;  Q5NYP6, RNH_AROAE  ;  A1URX4, RNH_BARBK  ;
DR   Q6G4C3, RNH_BARHE  ;  Q6G0C8, RNH_BARQU  ;  A9IQR5, RNH_BART1  ;
DR   Q1LT02, RNH_BAUCH  ;  Q7VQB6, RNH_BLOFL  ;  Q493H7, RNH_BLOPB  ;
DR   Q2KV56, RNH_BORA1  ;  Q7WCJ8, RNH_BORBR  ;  Q7VRX8, RNH_BORPE  ;
DR   P13319, RNH_BPT4   ;  Q89UU3, RNH_BRAJA  ;  A5EAL2, RNH_BRASB  ;
DR   A4Z216, RNH_BRASO  ;  Q2YMI3, RNH_BRUA2  ;  Q57EP4, RNH_BRUAB  ;
DR   P66673, RNH_BRUME  ;  A5VP47, RNH_BRUO2  ;  B0CKG2, RNH_BRUSI  ;
DR   P66674, RNH_BRUSU  ;  Q08885, RNH_BUCAP  ;  P59434, RNH_BUCBP  ;
DR   A4XKQ3, RNH_CALS8  ;  A8Z6F7, RNH_CAMC1  ;  A7H185, RNH_CAMC5  ;
DR   A8FNU8, RNH_CAMJ8  ;  Q9PM39, RNH_CAMJE  ;  A1W1N8, RNH_CAMJJ  ;
DR   Q5HSF7, RNH_CAMJR  ;  B8H4W7, RNH_CAUCN  ;  Q9A341, RNH_CAUCR  ;
DR   B0T025, RNH_CAUSK  ;  Q3APT0, RNH_CHLCH  ;  B3EH35, RNH_CHLL2  ;
DR   B3QM41, RNH_CHLP8  ;  B3EMT1, RNH_CHLPB  ;  A1BE10, RNH_CHLPD  ;
DR   Q1QW64, RNH_CHRSD  ;  Q7NYL8, RNH_CHRVO  ;  A8AKR0, RNH_CITK8  ;
DR   A7FR34, RNH_CLOB1  ;  A5HYU6, RNH_CLOBH  ;  A7GAG3, RNH_CLOBL  ;
DR   A9KLJ9, RNH_CLOPH  ;  A3DD79, RNH_CLOTH  ;  B6J5V1, RNH_COXB1  ;
DR   B6J1Y7, RNH_COXB2  ;  A9KGQ0, RNH_COXBN  ;  A9NB52, RNH_COXBR  ;
DR   Q83EK3, RNH_COXBU  ;  Q0K8W6, RNH_CUPNH  ;  Q46Z81, RNH_CUPPJ  ;
DR   B8HPS9, RNH_CYAP4  ;  B7JVG1, RNH_CYAP8  ;  Q47FN9, RNH_DECAR  ;
DR   Q30X61, RNH_DESDG  ;  A4J7B3, RNH_DESRM  ;  Q72E89, RNH_DESVH  ;
DR   B8DIU7, RNH_DESVM  ;  A1VFS4, RNH_DESVV  ;  A5EXP9, RNH_DICNV  ;
DR   A8LLC1, RNH_DINSH  ;  A7ZHV1, RNH_ECO24  ;  B7UJB0, RNH_ECO27  ;
DR   B7MBJ0, RNH_ECO45  ;  B7LHC0, RNH_ECO55  ;  P0A7Y6, RNH_ECO57  ;
DR   B5Z0I8, RNH_ECO5E  ;  B7NKW4, RNH_ECO7I  ;  B7MQ23, RNH_ECO81  ;
DR   B7M213, RNH_ECO8A  ;  C4ZRV1, RNH_ECOBW  ;  B1XD78, RNH_ECODH  ;
DR   A7ZWF6, RNH_ECOHS  ;  Q0TLC3, RNH_ECOL5  ;  P0A7Y5, RNH_ECOL6  ;
DR   B1IPU4, RNH_ECOLC  ;  P0A7Y4, RNH_ECOLI  ;  B7N876, RNH_ECOLU  ;
DR   B6HZS7, RNH_ECOSE  ;  B1LHM3, RNH_ECOSM  ;  C5BEV5, RNH_EDWI9  ;
DR   Q3YR62, RNH_EHRCJ  ;  Q2GHJ9, RNH_EHRCR  ;  Q5FG88, RNH_EHRRG  ;
DR   A4W6V4, RNH_ENT38  ;  A7MI34, RNH_ENTS8  ;  Q6D1V7, RNH_ERWCT  ;
DR   B2VHJ5, RNH_ERWT9  ;  Q2ND39, RNH_ERYLH  ;  B7LW89, RNH_ESCF3  ;
DR   Q0RJ31, RNH_FRAAA  ;  B0TZ91, RNH_FRAP2  ;  Q14IN1, RNH_FRAT1  ;
DR   A7NBM9, RNH_FRATF  ;  Q2A3X6, RNH_FRATH  ;  B2SFV9, RNH_FRATM  ;
DR   A0Q6W0, RNH_FRATN  ;  Q0BMB7, RNH_FRATO  ;  A4IYE6, RNH_FRATW  ;
DR   Q39X47, RNH_GEOMG  ;  Q74BH0, RNH_GEOSL  ;  A5G5F6, RNH_GEOUR  ;
DR   Q5FUH9, RNH_GLUOX  ;  Q0BQX7, RNH_GRABC  ;  Q7VM15, RNH_HAEDU  ;
DR   Q4QP49, RNH_HAEI8  ;  A5UFU3, RNH_HAEIG  ;  P43807, RNH_HAEIN  ;
DR   Q2SJ45, RNH_HAHCH  ;  A1WXD7, RNH_HALHL  ;  Q17XJ7, RNH_HELAH  ;
DR   Q1CTK9, RNH_HELPH  ;  Q9ZLH3, RNH_HELPJ  ;  P56120, RNH_HELPY  ;
DR   A4G7G3, RNH_HERAR  ;  Q0C3M1, RNH_HYPNA  ;  Q5QZL3, RNH_IDILO  ;
DR   A6SXA4, RNH_JANMA  ;  Q28V43, RNH_JANSC  ;  B5Y1G2, RNH_KLEP3  ;
DR   A6T512, RNH_KLEP7  ;  Q5X5I2, RNH_LEGPA  ;  A5IBM5, RNH_LEGPC  ;
DR   Q5ZVQ7, RNH_LEGPH  ;  Q5WWW5, RNH_LEGPL  ;  Q2W9A9, RNH_MAGSA  ;
DR   Q65S82, RNH_MANSM  ;  A1U0U9, RNH_MARAV  ;  Q0AMI4, RNH_MARMM  ;
DR   Q11KC5, RNH_MESSB  ;  Q60AW8, RNH_METCA  ;  A9W185, RNH_METEP  ;
DR   Q1H190, RNH_METFK  ;  Q5UPY1, RNH_MIMIV  ;  Q2RKU0, RNH_MOOTA  ;
DR   A4T6Y5, RNH_MYCGI  ;  A0R3Q8, RNH_MYCS2  ;  Q07705, RNH_MYCSM  ;
DR   Q5F7K9, RNH_NEIG1  ;  Q9JTD9, RNH_NEIMA  ;  Q9JYE5, RNH_NEIMB  ;
DR   A1KV38, RNH_NEIMF  ;  Q2GDA1, RNH_NEOSM  ;  Q0AE34, RNH_NITEC  ;
DR   Q82XV8, RNH_NITEU  ;  Q1QH30, RNH_NITHX  ;  Q2Y8K1, RNH_NITMU  ;
DR   Q3J7D4, RNH_NITOC  ;  Q3SP51, RNH_NITWN  ;  Q2G9E3, RNH_NOVAD  ;
DR   A6WWG8, RNH_OCHA4  ;  B6JJ39, RNH_OLICO  ;  A5CEP5, RNH_ORITB  ;
DR   A1B840, RNH_PARDP  ;  A7HQX4, RNH_PARL1  ;  P57813, RNH_PASMU  ;
DR   C6DC65, RNH_PECCP  ;  Q3A827, RNH_PELCD  ;  Q3B2H0, RNH_PELLD  ;
DR   A1AT66, RNH_PELPD  ;  B4R8T3, RNH_PHEZH  ;  Q7N807, RNH_PHOLL  ;
DR   Q8GF77, RNH_PHOLU  ;  A1VMW5, RNH_POLNA  ;  Q12B88, RNH_POLSJ  ;
DR   A4SXM6, RNH_POLSQ  ;  B4S5K2, RNH_PROA2  ;  A2C030, RNH_PROM1  ;
DR   Q7VDY9, RNH_PROMA  ;  B4EUG3, RNH_PROMH  ;  Q46HH3, RNH_PROMT  ;
DR   A4SFZ9, RNH_PROVI  ;  Q48KX6, RNH_PSE14  ;  Q15TA7, RNH_PSEA6  ;
DR   A6V705, RNH_PSEA7  ;  B7VB62, RNH_PSEA8  ;  Q02KV8, RNH_PSEAB  ;
DR   Q9I2S9, RNH_PSEAE  ;  Q1I7T4, RNH_PSEE4  ;  Q4KBI1, RNH_PSEF5  ;
DR   Q3IIS1, RNH_PSEHT  ;  A4XU11, RNH_PSEMY  ;  A5W169, RNH_PSEP1  ;
DR   Q3KE77, RNH_PSEPF  ;  B0KN00, RNH_PSEPG  ;  Q88FF5, RNH_PSEPK  ;
DR   B1JBN1, RNH_PSEPW  ;  Q87YT0, RNH_PSESM  ;  Q4ZVL1, RNH_PSEU2  ;
DR   A4VLR0, RNH_PSEU5  ;  A1SS86, RNH_PSYIN  ;  Q1LL89, RNH_RALME  ;
DR   Q8XZ91, RNH_RALSO  ;  Q2KBL2, RNH_RHIEC  ;  Q1MKH6, RNH_RHIL3  ;
DR   Q985W1, RNH_RHILO  ;  Q92RG0, RNH_RHIME  ;  Q7UF86, RNH_RHOBA  ;
DR   Q21YF6, RNH_RHOFD  ;  Q2J0F8, RNH_RHOP2  ;  Q6N1Y3, RNH_RHOPA  ;
DR   Q131J2, RNH_RHOPS  ;  B3Q6U1, RNH_RHOPT  ;  Q2RPU6, RNH_RHORT  ;
DR   A3PMR3, RNH_RHOS1  ;  A4WNV1, RNH_RHOS5  ;  A8GPT6, RNH_RICAH  ;
DR   Q1RJL7, RNH_RICBR  ;  A8EXT7, RNH_RICCK  ;  Q92GL5, RNH_RICCN  ;
DR   Q4UN27, RNH_RICFE  ;  A8F2L0, RNH_RICM5  ;  Q9ZCK3, RNH_RICPR  ;
DR   Q68W20, RNH_RICTY  ;  Q16AK0, RNH_ROSDO  ;  A1AW38, RNH_RUTMC  ;
DR   A4FMU3, RNH_SACEN  ;  B5F8X2, RNH_SALA4  ;  A9MPF1, RNH_SALAR  ;
DR   Q57SZ6, RNH_SALCH  ;  B5FJ58, RNH_SALDC  ;  B5R449, RNH_SALEP  ;
DR   B5R5L3, RNH_SALG2  ;  B4TK85, RNH_SALHS  ;  B4SV39, RNH_SALNS  ;
DR   Q5PFD8, RNH_SALPA  ;  A9MZ19, RNH_SALPB  ;  C0Q6N2, RNH_SALPC  ;
DR   B5BDW5, RNH_SALPK  ;  B4TYH0, RNH_SALSV  ;  P0A2C0, RNH_SALTI  ;
DR   P0A2B9, RNH_SALTY  ;  A8GA77, RNH_SERP5  ;  A1S6T0, RNH_SHEAM  ;
DR   B8E599, RNH_SHEB2  ;  A3D440, RNH_SHEB5  ;  A6WMW8, RNH_SHEB8  ;
DR   A9L0F2, RNH_SHEB9  ;  Q12MM4, RNH_SHEDO  ;  Q081L4, RNH_SHEFN  ;
DR   B0TRM1, RNH_SHEHH  ;  A3QET0, RNH_SHELP  ;  Q8EE30, RNH_SHEON  ;
DR   A4Y6C1, RNH_SHEPC  ;  A0KXS6, RNH_SHESA  ;  A8FUS8, RNH_SHESH  ;
DR   Q0HI86, RNH_SHESM  ;  Q0HUI2, RNH_SHESR  ;  A1RK75, RNH_SHESW  ;
DR   B1KHK0, RNH_SHEWM  ;  B2U352, RNH_SHIB3  ;  Q325T2, RNH_SHIBS  ;
DR   Q32JP9, RNH_SHIDS  ;  P0A7Y7, RNH_SHIFL  ;  Q3Z5E9, RNH_SHISS  ;
DR   Q5LNJ2, RNH_SILPO  ;  Q1GDG1, RNH_SILST  ;  A6U6V5, RNH_SINMW  ;
DR   Q2NVF9, RNH_SODGM  ;  Q01RW8, RNH_SOLUE  ;  Q9X7R6, RNH_STRCO  ;
DR   A6QCI9, RNH_SULNB  ;  Q67K93, RNH_SYMTH  ;  Q2LWY9, RNH_SYNAS  ;
DR   A0LGJ7, RNH_SYNFM  ;  Q0AV47, RNH_SYNWW  ;  Q55801, RNH_SYNY3  ;
DR   Q8DM24, RNH_THEEB  ;  B0K9M0, RNH_THEP3  ;  B0K1A7, RNH_THEPX  ;
DR   Q72IE1, RNH_THET2  ;  P29253, RNH_THET8  ;  Q8RA67, RNH_THETN  ;
DR   Q31H49, RNH_THICR  ;  Q3SIB2, RNH_THIDA  ;  C4LC60, RNH_TOLAT  ;
DR   Q73K21, RNH_TREDE  ;  O83372, RNH_TREPA  ;  B2S2V0, RNH_TREPS  ;
DR   Q115G0, RNH_TRIEI  ;  Q83HK9, RNH_TROW8  ;  Q83GM3, RNH_TROWT  ;
DR   A1WFG9, RNH_VEREI  ;  A5CX29, RNH_VESOH  ;  A5F633, RNH_VIBC3  ;
DR   Q9KPX8, RNH_VIBCH  ;  C3LPN8, RNH_VIBCM  ;  Q5E3G5, RNH_VIBF1  ;
DR   A7MY21, RNH_VIBHB  ;  Q87MG2, RNH_VIBPA  ;  B7VIP1, RNH_VIBSL  ;
DR   Q8DBD5, RNH_VIBVU  ;  Q7MII6, RNH_VIBVY  ;  Q8D3D3, RNH_WIGBR  ;
DR   Q73I74, RNH_WOLPM  ;  C0R2X2, RNH_WOLWR  ;  Q8PNH8, RNH_XANAC  ;
DR   Q3BWP3, RNH_XANC5  ;  Q4URM3, RNH_XANC8  ;  Q8PBX8, RNH_XANCP  ;
DR   Q2P6Y2, RNH_XANOM  ;  Q5H426, RNH_XANOR  ;  Q9PBI6, RNH_XYLFA  ;
DR   Q87C76, RNH_XYLFT  ;  A1JKB1, RNH_YERE8  ;  A7FFK7, RNH_YERP3  ;
DR   Q1CAJ5, RNH_YERPA  ;  B2KAC9, RNH_YERPB  ;  Q8ZH30, RNH_YERPE  ;
DR   A9R0G0, RNH_YERPG  ;  Q1CFI6, RNH_YERPN  ;  A4TL54, RNH_YERPP  ;
DR   Q667M7, RNH_YERPS  ;  B1JR46, RNH_YERPY  ;  O69014, RNH_ZYMMO  ;
DR   P21325, RT67_ECOLX ;  Q07163, TY1AB_YEASX;  O13527, YA11B_YEAST;
DR   Q12490, YB11B_YEAST;  Q12193, YB12B_YEAST;  Q12491, YB21B_YEAST;
DR   P25384, YC21B_YEAST;  Q03855, YD11B_YEAST;  Q99231, YD12B_YEAST;
DR   Q07793, YD13B_YEAST;  P0C2I2, YD14B_YEAST;  P0C2I3, YD15B_YEAST;
DR   Q12472, YD21B_YEAST;  Q03494, YD22B_YEAST;  Q07791, YD23B_YEAST;
DR   Q03612, YE11B_YEAST;  Q03619, YE12B_YEAST;  P0CX63, YF21B_YEAST;
DR   Q12141, YG11B_YEAST;  Q12269, YG12B_YEAST;  Q12316, YG13B_YEAST;
DR   Q12337, YG21B_YEAST;  P0CX64, YG22B_YEAST;  Q99315, YG31B_YEAST;
DR   O13535, YH11B_YEAST;  Q7LHG5, YI31B_YEAST;  P47098, YJ11B_YEAST;
DR   P47100, YJ12B_YEAST;  Q12088, YL11B_YEAST;  P0C2I5, YL12B_YEAST;
DR   P0C2I6, YL13B_YEAST;  P0C2I7, YL14B_YEAST;  P0C2J3, YL21B_YEAST;
DR   P0C2J5, YL22B_YEAST;  Q04711, YM11B_YEAST;  Q03434, YM12B_YEAST;
DR   Q04214, YM13B_YEAST;  Q04670, YM14B_YEAST;  Q12112, YN11B_YEAST;
DR   Q99337, YN12B_YEAST;  Q12273, YO11B_YEAST;  Q92393, YO12B_YEAST;
DR   Q12113, YO21B_YEAST;  Q12501, YO22B_YEAST;  Q12414, YP11B_YEAST;
DR   P0C2I9, YP12B_YEAST;  P0C2J0, YP13B_YEAST;  P0C2J1, YP14B_YEAST;
//
ID   3.1.26.5
DE   Ribonuclease P.
CA   Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA
CA   precursor.
CC   -!- Essential for tRNA processing; generates 5'-termini of mature tRNA
CC       molecules.
PR   PROSITE; PDOC00558;
DR   Q99575, POP1_HUMAN ;  P41812, POP1_YEAST ;  Q6AWV1, POP5_ARATH ;
DR   Q1JQ92, POP5_BOVIN ;  Q5BJI6, POP5_DANRE ;  Q54EP3, POP5_DICDI ;
DR   Q969H6, POP5_HUMAN ;  Q9DB28, POP5_MOUSE ;  Q9UU90, POP5_SCHPO ;
DR   P28005, POP5_YEAST ;  P53218, POP6_YEAST ;  Q0II25, POP7_BOVIN ;
DR   O75817, POP7_HUMAN ;  Q9DCH2, POP7_MOUSE ;  P38291, POP7_YEAST ;
DR   Q7Z996, POP8_SCHPO ;  P38208, POP8_YEAST ;  Q9UTA4, POPI_SCHPO ;
DR   Q9YF79, RNP1_AERPE ;  O28362, RNP1_ARCFU ;  B8D5W2, RNP1_DESK1 ;
DR   P22527, RNP1_HALMA ;  B0R664, RNP1_HALS3 ;  O24785, RNP1_HALSA ;
DR   A2BMC7, RNP1_HYPBU ;  A8AA22, RNP1_IGNH4 ;  A6UWU6, RNP1_META3 ;
DR   Q8TRT9, RNP1_METAC ;  Q46GA3, RNP1_METBF ;  Q12ZU3, RNP1_METBU ;
DR   Q57903, RNP1_METJA ;  Q8TGY6, RNP1_METKA ;  Q8PV42, RNP1_METMA ;
DR   P60832, RNP1_METMP ;  A5UL80, RNP1_METS3 ;  Q2NFW5, RNP1_METST ;
DR   O26119, RNP1_METTH ;  P14022, RNP1_METVA ;  A6UQ52, RNP1_METVS ;
DR   A9A5I7, RNP1_NITMS ;  Q9V1U4, RNP1_PYRAB ;  Q8U007, RNP1_PYRFU ;
DR   O59425, RNP1_PYRHO ;  Q5JDH8, RNP1_PYRKO ;  Q9P7W9, RNP1_SCHPO ;
DR   A3DNB5, RNP1_STAMF ;  P60833, RNP1_SULSO ;  P60834, RNP1_SULTO ;
DR   P60835, RNP1_THEAC ;  B6YSM2, RNP1_THEON ;  A1RXG4, RNP1_THEPD ;
DR   C6A168, RNP1_THESM ;  Q97BW8, RNP1_THEVO ;  Q9YCV1, RNP2_AERPE ;
DR   O29761, RNP2_ARCFU ;  B9LMH2, RNP2_HALLT ;  Q5V2X7, RNP2_HALMA ;
DR   B0R594, RNP2_HALS3 ;  Q9HQ86, RNP2_HALSA ;  A6UVH2, RNP2_META3 ;
DR   Q8TPX3, RNP2_METAC ;  Q469M7, RNP2_METBF ;  Q57917, RNP2_METJA ;
DR   Q8TYB6, RNP2_METKA ;  A2ST53, RNP2_METLZ ;  A4FXR3, RNP2_METM5 ;
DR   A9AB65, RNP2_METM6 ;  A6VFH0, RNP2_METM7 ;  Q8PTU2, RNP2_METMA ;
DR   A3CW56, RNP2_METMJ ;  P60780, RNP2_METMP ;  B8GEZ4, RNP2_METPE ;
DR   A5UJS3, RNP2_METS3 ;  O26783, RNP2_METTH ;  A6UN85, RNP2_METVS ;
DR   Q3IPJ2, RNP2_NATPD ;  Q9V0V4, RNP2_PYRAB ;  Q8U151, RNP2_PYRFU ;
DR   O59150, RNP2_PYRHO ;  Q5JJ62, RNP2_PYRKO ;  C3N5Q9, RNP2_SULIA ;
DR   C4KHD8, RNP2_SULIK ;  C3MQ42, RNP2_SULIL ;  C3MVG0, RNP2_SULIM ;
DR   C3NHC7, RNP2_SULIN ;  C3NEC5, RNP2_SULIY ;  Q9UXC7, RNP2_SULSO ;
DR   Q975G4, RNP2_SULTO ;  C5A4D6, RNP2_THEGJ ;  B6YV61, RNP2_THEON ;
DR   C6A460, RNP2_THESM ;  Q9YC00, RNP3_AERPE ;  O27967, RNP3_ARCFU ;
DR   B9LMH0, RNP3_HALLT ;  Q5V2X5, RNP3_HALMA ;  B0R596, RNP3_HALS3 ;
DR   Q8TPX2, RNP3_METAC ;  Q469M8, RNP3_METBF ;  Q12ZC2, RNP3_METBU ;
DR   Q58539, RNP3_METJA ;  Q8TYB5, RNP3_METKA ;  A4FZ71, RNP3_METM5 ;
DR   A9A6K3, RNP3_METM6 ;  A6VJ64, RNP3_METM7 ;  Q8PTU3, RNP3_METMA ;
DR   P60781, RNP3_METMP ;  O26784, RNP3_METTH ;  A6US39, RNP3_METVS ;
DR   Q3IPJ7, RNP3_NATPD ;  Q9UXX7, RNP3_PYRAB ;  Q8TZS0, RNP3_PYRFU ;
DR   O59543, RNP3_PYRHO ;  Q5JH47, RNP3_PYRKO ;  P87120, RNP3_SCHPO ;
DR   C5A1N9, RNP3_THEGJ ;  Q9YD20, RNP4_AERPE ;  O30127, RNP4_ARCFU ;
DR   B0R3R4, RNP4_HALS3 ;  Q9HRP7, RNP4_HALSA ;  A2BN51, RNP4_HYPBU ;
DR   Q8TTY5, RNP4_METAC ;  A7I9J3, RNP4_METB6 ;  Q46D07, RNP4_METBF ;
DR   Q12VV9, RNP4_METBU ;  Q2FTK3, RNP4_METHJ ;  Q58372, RNP4_METJA ;
DR   Q8TGY1, RNP4_METKA ;  A2STJ3, RNP4_METLZ ;  A4FXV4, RNP4_METM5 ;
DR   A9AB23, RNP4_METM6 ;  A6VFL2, RNP4_METM7 ;  Q8PWM8, RNP4_METMA ;
DR   A3CX01, RNP4_METMJ ;  P62378, RNP4_METMP ;  B8GET9, RNP4_METPE ;
DR   A5UL38, RNP4_METS3 ;  Q2NGR3, RNP4_METST ;  O27655, RNP4_METTH ;
DR   A6UNQ2, RNP4_METVS ;  Q6KZ41, RNP4_PICTO ;  Q9V166, RNP4_PYRAB ;
DR   Q8U0H6, RNP4_PYRFU ;  O59248, RNP4_PYRHO ;  Q5JEC9, RNP4_PYRKO ;
DR   Q4JCL6, RNP4_SULAC ;  C3MZY6, RNP4_SULIA ;  C4KJF8, RNP4_SULIK ;
DR   C3MJB8, RNP4_SULIL ;  C3MTQ0, RNP4_SULIM ;  C3NJ74, RNP4_SULIN ;
DR   C3N7W8, RNP4_SULIY ;  Q97WJ1, RNP4_SULSO ;  Q96YP3, RNP4_SULTO ;
DR   Q9HLQ1, RNP4_THEAC ;  C6A4A4, RNP4_THESM ;  Q97C23, RNP4_THEVO ;
DR   A9NE63, RNPA_ACHLI ;  Q6F6K8, RNPA_ACIAD ;  B0VQP7, RNPA_ACIBS ;
DR   B0V5R2, RNPA_ACIBY ;  A0LWX2, RNPA_ACIC1 ;  A0KQZ9, RNPA_AERHH ;
DR   A4STS7, RNPA_AERS4 ;  Q8UIB2, RNPA_AGRT5 ;  Q0VKU6, RNPA_ALCBS ;
DR   B6EP41, RNPA_ALISL ;  A6TXE9, RNPA_ALKMQ ;  A8MKS3, RNPA_ALKOO ;
DR   Q3M7J6, RNPA_ANAVT ;  B7GMW3, RNPA_ANOFW ;  Q5P4P2, RNPA_AROAE ;
DR   B8H8Z3, RNPA_ARTCA ;  A0K2M6, RNPA_ARTS2 ;  A1KCQ1, RNPA_AZOSB ;
DR   C1DNF9, RNPA_AZOVD ;  A7ZAW4, RNPA_BACA2 ;  C3P3F8, RNPA_BACAA ;
DR   C3LGU4, RNPA_BACAC ;  Q81JH0, RNPA_BACAN ;  B7JIL4, RNPA_BACC0 ;
DR   Q72WU0, RNPA_BACC1 ;  B7IST7, RNPA_BACC2 ;  C1ER80, RNPA_BACC3 ;
DR   B7H7A5, RNPA_BACC4 ;  B7HZH3, RNPA_BACC7 ;  A7GVQ0, RNPA_BACCN ;
DR   B9IT45, RNPA_BACCQ ;  Q814F3, RNPA_BACCR ;  Q630B5, RNPA_BACCZ ;
DR   Q9RCA4, RNPA_BACHD ;  Q6HAE9, RNPA_BACHK ;  A8FJG3, RNPA_BACP2 ;
DR   Q5WAG0, RNPA_BACSK ;  P25814, RNPA_BACSU ;  A9VTM3, RNPA_BACWK ;
DR   Q6G2G7, RNPA_BARHE ;  Q6FZ17, RNPA_BARQU ;  Q1LTW1, RNPA_BAUCH ;
DR   C5C6N8, RNPA_BEUC1 ;  B8DV04, RNPA_BIFA0 ;  A1A3X8, RNPA_BIFAA ;
DR   B3DP24, RNPA_BIFLD ;  Q8G6J8, RNPA_BIFLO ;  B7GPF7, RNPA_BIFLS ;
DR   Q7VQV1, RNPA_BLOFL ;  Q494B8, RNPA_BLOPB ;  Q2KTI7, RNPA_BORA1 ;
DR   Q0SN68, RNPA_BORAP ;  Q7WDJ7, RNPA_BORBR ;  P50069, RNPA_BORBU ;
DR   B7J207, RNPA_BORBZ ;  B5RLZ8, RNPA_BORDL ;  Q661I0, RNPA_BORGA ;
DR   B2S0E4, RNPA_BORHD ;  Q7W2K3, RNPA_BORPA ;  A9IJC1, RNPA_BORPD ;
DR   Q7VSD8, RNPA_BORPE ;  B5RRP4, RNPA_BORRA ;  A1QZM7, RNPA_BORT9 ;
DR   C0ZA70, RNPA_BREBN ;  A9MCU8, RNPA_BRUC2 ;  C0RMG2, RNPA_BRUMB ;
DR   Q8YDA2, RNPA_BRUME ;  A9WW33, RNPA_BRUSI ;  Q8FV30, RNPA_BRUSU ;
DR   P57130, RNPA_BUCAI ;  P29433, RNPA_BUCAP ;  P59413, RNPA_BUCBP ;
DR   A3MS22, RNPA_BURM7 ;  A2S8D4, RNPA_BURM9 ;  Q62EM2, RNPA_BURMA ;
DR   A1V7D7, RNPA_BURMS ;  A3NPW9, RNPA_BURP0 ;  A3N475, RNPA_BURP6 ;
DR   Q63YW3, RNPA_BURPS ;  Q13SH2, RNPA_BURXL ;  A8FM14, RNPA_CAMJ8 ;
DR   A7H368, RNPA_CAMJD ;  Q9PNX5, RNPA_CAMJE ;  A1VZV1, RNPA_CAMJJ ;
DR   Q5HUJ9, RNPA_CAMJR ;  Q3AG60, RNPA_CARHZ ;  B8H1E9, RNPA_CAUCN ;
DR   Q9AA39, RNPA_CAUCR ;  A9WBG7, RNPA_CHLAA ;  Q5L548, RNPA_CHLAB ;
DR   B8G7S5, RNPA_CHLAD ;  Q821V0, RNPA_CHLCV ;  Q255T8, RNPA_CHLFF ;
DR   Q9PLD7, RNPA_CHLMU ;  A1BJZ9, RNPA_CHLPD ;  Q9Z6X2, RNPA_CHLPN ;
DR   B9LGI0, RNPA_CHLSY ;  B0B910, RNPA_CHLT2 ;  Q3KKQ8, RNPA_CHLTA ;
DR   B0BAN9, RNPA_CHLTB ;  Q8KGG4, RNPA_CHLTE ;  O84789, RNPA_CHLTR ;
DR   Q1QS97, RNPA_CHRSD ;  Q7NPT6, RNPA_CHRVO ;  A8ACL6, RNPA_CITK8 ;
DR   A5CVC5, RNPA_CLAM3 ;  Q97CV8, RNPA_CLOAB ;  A7FPL5, RNPA_CLOB1 ;
DR   C3KWJ9, RNPA_CLOB6 ;  A6M3M9, RNPA_CLOB8 ;  B2V1V3, RNPA_CLOBA ;
DR   B2TRI3, RNPA_CLOBB ;  A5I820, RNPA_CLOBH ;  C1FP35, RNPA_CLOBJ ;
DR   B1IHS3, RNPA_CLOBK ;  A7GJP3, RNPA_CLOBL ;  B1KUB6, RNPA_CLOBM ;
DR   Q181T2, RNPA_CLOD6 ;  A5N455, RNPA_CLOK5 ;  A0PX73, RNPA_CLONN ;
DR   Q0TLZ0, RNPA_CLOP1 ;  Q8XH26, RNPA_CLOPE ;  A9KLY3, RNPA_CLOPH ;
DR   Q0SPP9, RNPA_CLOPS ;  B5Y9B9, RNPA_COPPD ;  C3PL13, RNPA_CORA7 ;
DR   Q6NE96, RNPA_CORDI ;  Q8FSU8, RNPA_COREF ;  A4QIE5, RNPA_CORGB ;
DR   Q8NL51, RNPA_CORGL ;  Q4JSC2, RNPA_CORJK ;  B1VJ37, RNPA_CORU7 ;
DR   A9KBT3, RNPA_COXBN ;  A9NBA3, RNPA_COXBR ;  P45648, RNPA_COXBU ;
DR   B8HR50, RNPA_CYAP4 ;  B7KHE3, RNPA_CYAP7 ;  B7K5U5, RNPA_CYAP8 ;
DR   Q3Z7P1, RNPA_DEHE1 ;  Q3ZY16, RNPA_DEHSC ;  Q1IY22, RNPA_DEIGD ;
DR   Q9RSH3, RNPA_DEIRA ;  B8FMU9, RNPA_DESAA ;  C6C0J4, RNPA_DESAD ;
DR   C0QIZ3, RNPA_DESAH ;  B8J2U6, RNPA_DESDA ;  Q30YQ3, RNPA_DESDG ;
DR   A8ZRZ3, RNPA_DESOH ;  Q6APZ0, RNPA_DESPS ;  A4J9S4, RNPA_DESRM ;
DR   B5YBN8, RNPA_DICT6 ;  B8DYS1, RNPA_DICTD ;  A7ZTR0, RNPA_ECO24 ;
DR   B7UMH1, RNPA_ECO27 ;  B7MGC5, RNPA_ECO45 ;  B7L844, RNPA_ECO55 ;
DR   Q8XB43, RNPA_ECO57 ;  B5YXA8, RNPA_ECO5E ;  B7NR06, RNPA_ECO7I ;
DR   B7N2E9, RNPA_ECO81 ;  B7M556, RNPA_ECO8A ;  C4ZYY1, RNPA_ECOBW ;
DR   B1X9T2, RNPA_ECODH ;  A8A6G5, RNPA_ECOHS ;  A1AHN8, RNPA_ECOK1 ;
DR   Q8FBV5, RNPA_ECOL6 ;  P0A7Y8, RNPA_ECOLI ;  B7NF21, RNPA_ECOLU ;
DR   B6I3T7, RNPA_ECOSE ;  B1LL31, RNPA_ECOSM ;  Q1R4N2, RNPA_ECOUT ;
DR   C5BF62, RNPA_EDWI9 ;  Q82YV0, RNPA_ENTFA ;  A7MN01, RNPA_ENTS8 ;
DR   Q6CYR1, RNPA_ERWCT ;  B2VCE5, RNPA_ERWT9 ;  Q2N7X0, RNPA_ERYLH ;
DR   B7LK46, RNPA_ESCF3 ;  B1YGB0, RNPA_EXIS2 ;  C4KZZ5, RNPA_EXISA ;
DR   B0S3V6, RNPA_FINM2 ;  A8L8W2, RNPA_FRASN ;  Q8RHA6, RNPA_FUSNN ;
DR   B5EGY0, RNPA_GEOBB ;  Q5KU54, RNPA_GEOKA ;  C6DYS3, RNPA_GEOSM ;
DR   C5D9Z1, RNPA_GEOSW ;  A4ITX4, RNPA_GEOTN ;  A5G9V6, RNPA_GEOUR ;
DR   A9HKS8, RNPA_GLUDA ;  Q5FPY1, RNPA_GLUOX ;  Q7VN34, RNPA_HAEDU ;
DR   Q4QLR2, RNPA_HAEI8 ;  A5UID3, RNPA_HAEIG ;  P44306, RNPA_HAEIN ;
DR   Q0I0Y9, RNPA_HAES1 ;  B0URU5, RNPA_HAES2 ;  A1WWE2, RNPA_HALHL ;
DR   C4K7P7, RNPA_HAMD5 ;  Q17ZA3, RNPA_HELAH ;  Q7VJX7, RNPA_HELHP ;
DR   B6JNU5, RNPA_HELP2 ;  Q1CRI1, RNPA_HELPH ;  Q9ZJH0, RNPA_HELPJ ;
DR   B2UVJ3, RNPA_HELPS ;  P55997, RNPA_HELPY ;  A9AXK0, RNPA_HERA2 ;
DR   Q5QZK1, RNPA_IDILO ;  A6WGN2, RNPA_KINRD ;  B5XZP6, RNPA_KLEP3 ;
DR   B2GJF5, RNPA_KOCRD ;  Q5FHQ3, RNPA_LACAC ;  Q03N61, RNPA_LACBA ;
DR   B3WBV6, RNPA_LACCB ;  Q1G7Z2, RNPA_LACDA ;  Q047F7, RNPA_LACDB ;
DR   B2GEU6, RNPA_LACF3 ;  Q040F1, RNPA_LACGA ;  A8YTQ9, RNPA_LACH4 ;
DR   Q74H92, RNPA_LACJO ;  Q9CJ73, RNPA_LACLA ;  A2RHL3, RNPA_LACLM ;
DR   Q032X2, RNPA_LACLS ;  Q88RX0, RNPA_LACPL ;  A5VMV1, RNPA_LACRD ;
DR   B2GA53, RNPA_LACRJ ;  Q1WRF9, RNPA_LACS1 ;  Q38UE4, RNPA_LACSS ;
DR   Q5X0M0, RNPA_LEGPA ;  A5IIK5, RNPA_LEGPC ;  Q5WSE7, RNPA_LEGPL ;
DR   B1MWS3, RNPA_LEUCK ;  Q03UI9, RNPA_LEUMM ;  Q926Q4, RNPA_LISIN ;
DR   C1L0I8, RNPA_LISMC ;  Q71VQ7, RNPA_LISMF ;  B8DCV5, RNPA_LISMH ;
DR   Q8Y3I1, RNPA_LISMO ;  A0AMG4, RNPA_LISW6 ;  B9E8Z6, RNPA_MACCJ ;
DR   Q2VZ17, RNPA_MAGSA ;  Q65VC0, RNPA_MANSM ;  A1U7J6, RNPA_MARAV ;
DR   A6W3V2, RNPA_MARMS ;  Q6F0D5, RNPA_MESFL ;  Q11LE6, RNPA_MESSB ;
DR   Q602M8, RNPA_METCA ;  B0JN62, RNPA_MICAN ;  C5C7X2, RNPA_MICLC ;
DR   P21172, RNPA_MICLU ;  A0QND4, RNPA_MYCA1 ;  B1MN96, RNPA_MYCA9 ;
DR   P0A5X9, RNPA_MYCBO ;  P43039, RNPA_MYCCT ;  P47703, RNPA_MYCGE ;
DR   A4T4T3, RNPA_MYCGI ;  Q4A750, RNPA_MYCH7 ;  Q4A913, RNPA_MYCHJ ;
DR   B8ZTN6, RNPA_MYCLB ;  P46610, RNPA_MYCLE ;  B2HNT8, RNPA_MYCMM ;
DR   Q6KH14, RNPA_MYCMO ;  Q6MRS3, RNPA_MYCMS ;  Q9L7L9, RNPA_MYCPA ;
DR   Q8EU90, RNPA_MYCPE ;  P75111, RNPA_MYCPN ;  Q98R57, RNPA_MYCPU ;
DR   Q4A5G4, RNPA_MYCS5 ;  A3Q8S4, RNPA_MYCSJ ;  A1U8R8, RNPA_MYCSK ;
DR   Q1B0S2, RNPA_MYCSS ;  P0A5X8, RNPA_MYCTU ;  A0PX70, RNPA_MYCUA ;
DR   A1TI29, RNPA_MYCVP ;  B2A474, RNPA_NATTJ ;  Q5F4W3, RNPA_NEIG1 ;
DR   B4RJJ5, RNPA_NEIG2 ;  Q9JW46, RNPA_NEIMA ;  Q9JXS6, RNPA_NEIMB ;
DR   A1KS00, RNPA_NEIMF ;  Q0AE58, RNPA_NITEC ;  Q82X99, RNPA_NITEU ;
DR   Q3J6L7, RNPA_NITOC ;  A6Q3D2, RNPA_NITSB ;  Q5YMR7, RNPA_NOCFA ;
DR   A1SQV9, RNPA_NOCSJ ;  B2J0Q5, RNPA_NOSP7 ;  Q8YRN1, RNPA_NOSS1 ;
DR   Q8EKU0, RNPA_OCEIH ;  A6WYM5, RNPA_OCHA4 ;  Q04CX7, RNPA_OENOB ;
DR   Q6YQX5, RNPA_ONYPE ;  P57915, RNPA_PASMU ;  Q03D57, RNPA_PEDPA ;
DR   A5CY49, RNPA_PELTS ;  A9BJC4, RNPA_PETMO ;  Q7M7H7, RNPA_PHOLL ;
DR   Q6LW54, RNPA_PHOPR ;  B1VAN7, RNPA_PHYAS ;  B2RHI3, RNPA_PORG3 ;
DR   Q7MXI4, RNPA_PORGI ;  A3PE33, RNPA_PROM0 ;  A2C405, RNPA_PROM1 ;
DR   A8G5Y2, RNPA_PROM2 ;  A2C7A3, RNPA_PROM3 ;  A9BBJ0, RNPA_PROM4 ;
DR   A2BXQ2, RNPA_PROM5 ;  Q319V1, RNPA_PROM9 ;  Q7TVA1, RNPA_PROMA ;
DR   B4F0U3, RNPA_PROMH ;  P22835, RNPA_PROMI ;  Q7V612, RNPA_PROMM ;
DR   A2BSA0, RNPA_PROMS ;  Q46JN4, RNPA_PROMT ;  Q48BF0, RNPA_PSE14 ;
DR   Q15MS5, RNPA_PSEA6 ;  A6VF46, RNPA_PSEA7 ;  B7V7A6, RNPA_PSEA8 ;
DR   Q02DD9, RNPA_PSEAB ;  Q9HT05, RNPA_PSEAE ;  O86449, RNPA_PSEAO ;
DR   Q1I2H2, RNPA_PSEE4 ;  Q3IK52, RNPA_PSEHT ;  A4Y1A2, RNPA_PSEMY ;
DR   A5WBB9, RNPA_PSEP1 ;  Q3K426, RNPA_PSEPF ;  B0KEU7, RNPA_PSEPG ;
DR   P0A167, RNPA_PSEPK ;  P0A168, RNPA_PSEPU ;  Q87TR9, RNPA_PSESM ;
DR   A4VS84, RNPA_PSEU5 ;  A1T0M7, RNPA_PSYIN ;  A5WI39, RNPA_PSYWF ;
DR   B2U822, RNPA_RALPJ ;  Q1MM57, RNPA_RHIL3 ;  Q98D89, RNPA_RHILO ;
DR   Q92SF4, RNPA_RHIME ;  Q7UNR1, RNPA_RHOBA ;  C0ZVP7, RNPA_RHOE4 ;
DR   C1B7S5, RNPA_RHOOB ;  Q0SAG9, RNPA_RHOSR ;  C3PP52, RNPA_RICAE ;
DR   A8GP91, RNPA_RICAH ;  A8GVL0, RNPA_RICB8 ;  Q1RI66, RNPA_RICBR ;
DR   A8EY59, RNPA_RICCK ;  Q92H35, RNPA_RICCN ;  Q4UML0, RNPA_RICFE ;
DR   Q9ZCU8, RNPA_RICPR ;  C4K1K8, RNPA_RICPU ;  B0BUJ2, RNPA_RICRO ;
DR   A8GT00, RNPA_RICRS ;  Q68WC8, RNPA_RICTY ;  A7NJ53, RNPA_ROSCS ;
DR   A5V0B3, RNPA_ROSS1 ;  Q21DF8, RNPA_SACD2 ;  B5EYX4, RNPA_SALA4 ;
DR   A8LXK4, RNPA_SALAI ;  A9MJT8, RNPA_SALAR ;  B5FN12, RNPA_SALDC ;
DR   B5QUQ2, RNPA_SALEP ;  B5RFY5, RNPA_SALG2 ;  B4TAV1, RNPA_SALHS ;
DR   B4SYB0, RNPA_SALNS ;  Q5PKU4, RNPA_SALPA ;  B5BIL6, RNPA_SALPK ;
DR   B4TN09, RNPA_SALSV ;  P66687, RNPA_SALTI ;  A4XDK4, RNPA_SALTO ;
DR   P66686, RNPA_SALTY ;  A8G7Q0, RNPA_SERP5 ;  A1S1G7, RNPA_SHEAM ;
DR   B8EDW7, RNPA_SHEB2 ;  A3DAT0, RNPA_SHEB5 ;  A6WUK6, RNPA_SHEB8 ;
DR   A9KX22, RNPA_SHEB9 ;  Q12HM6, RNPA_SHEDO ;  Q07VS4, RNPA_SHEFN ;
DR   Q8EKT4, RNPA_SHEON ;  A4YCM4, RNPA_SHEPC ;  A0KR34, RNPA_SHESA ;
DR   Q0HD62, RNPA_SHESM ;  Q0HPE4, RNPA_SHESR ;  A1RQF1, RNPA_SHESW ;
DR   B1KQ67, RNPA_SHEWM ;  B2TUS4, RNPA_SHIB3 ;  Q31UV7, RNPA_SHIBS ;
DR   Q329B4, RNPA_SHIDS ;  P0A7Y9, RNPA_SHIFL ;  Q3YWB0, RNPA_SHISS ;
DR   Q5LW06, RNPA_SILPO ;  Q2NQ69, RNPA_SODGM ;  A7X7A9, RNPA_STAA1 ;
DR   A6U596, RNPA_STAA2 ;  Q2FDE7, RNPA_STAA3 ;  Q2FUQ1, RNPA_STAA8 ;
DR   A5IWD8, RNPA_STAA9 ;  Q2YZB7, RNPA_STAAB ;  Q5HCI2, RNPA_STAAC ;
DR   P66688, RNPA_STAAM ;  P66689, RNPA_STAAN ;  Q6GD91, RNPA_STAAR ;
DR   Q6G5W3, RNPA_STAAS ;  A8YYS2, RNPA_STAAT ;  P0A0H5, RNPA_STAAU ;
DR   P0A0H4, RNPA_STAAW ;  B9DI94, RNPA_STACT ;  Q5HS37, RNPA_STAEQ ;
DR   Q8CMN4, RNPA_STAES ;  Q4L2Z1, RNPA_STAHJ ;  Q3K2X6, RNPA_STRA1 ;
DR   Q8E6W5, RNPA_STRA3 ;  Q8E1E7, RNPA_STRA5 ;  Q82FE0, RNPA_STRAW ;
DR   P25817, RNPA_STRBI ;  P48206, RNPA_STRCO ;  C0M7E1, RNPA_STRE4 ;
DR   B4U0S7, RNPA_STREM ;  A8AUN9, RNPA_STRGC ;  B1VPE8, RNPA_STRGG ;
DR   B4SPG1, RNPA_STRM5 ;  Q8DVX4, RNPA_STRMU ;  Q9A1J4, RNPA_STRP1 ;
DR   Q04ID0, RNPA_STRP2 ;  P0DF24, RNPA_STRP3 ;  B5E2W2, RNPA_STRP4 ;
DR   Q5XDZ0, RNPA_STRP6 ;  C1CA87, RNPA_STRP7 ;  P66691, RNPA_STRP8 ;
DR   Q1JDN4, RNPA_STRPB ;  Q1JNK3, RNPA_STRPC ;  Q1JIQ1, RNPA_STRPD ;
DR   Q1J8K9, RNPA_STRPF ;  A2RCF8, RNPA_STRPG ;  B1I998, RNPA_STRPI ;
DR   B8ZPA3, RNPA_STRPJ ;  Q48VE1, RNPA_STRPM ;  Q97NI5, RNPA_STRPN ;
DR   P0DF25, RNPA_STRPQ ;  B2IML6, RNPA_STRPS ;  B5XJN7, RNPA_STRPZ ;
DR   Q8DN92, RNPA_STRR6 ;  C0MFG8, RNPA_STRS7 ;  Q5LY00, RNPA_STRT1 ;
DR   Q5M2K4, RNPA_STRT2 ;  Q03IQ0, RNPA_STRTD ;  B9DVV7, RNPA_STRU0 ;
DR   C1CGX2, RNPA_STRZJ ;  C1CMY8, RNPA_STRZP ;  C1CTU8, RNPA_STRZT ;
DR   Q67J29, RNPA_SYMTH ;  Q2LSG2, RNPA_SYNAS ;  Q31MS4, RNPA_SYNE7 ;
DR   A0LLH1, RNPA_SYNFM ;  Q2JQX0, RNPA_SYNJA ;  Q2JHS3, RNPA_SYNJB ;
DR   B1XJD2, RNPA_SYNP2 ;  Q5N605, RNPA_SYNP6 ;  A5GN10, RNPA_SYNPW ;
DR   Q7U524, RNPA_SYNPX ;  A5GRN3, RNPA_SYNR3 ;  Q3AV41, RNPA_SYNS9 ;
DR   Q0ATU2, RNPA_SYNWW ;  Q55005, RNPA_SYNY3 ;  Q7X5L4, RNPA_THEAQ ;
DR   Q7X5L6, RNPA_THEBO ;  Q7X5L2, RNPA_THEFI ;  Q47K73, RNPA_THEFY ;
DR   Q9X1H4, RNPA_THEMA ;  Q7X5L0, RNPA_THEOS ;  A5IMC2, RNPA_THEP1 ;
DR   B0K8I3, RNPA_THEP3 ;  B0K5N8, RNPA_THEPX ;  Q7X5K8, RNPA_THESC ;
DR   B1LBK1, RNPA_THESQ ;  Q72LI2, RNPA_THET2 ;  Q7X5K6, RNPA_THET8 ;
DR   Q8R6K4, RNPA_THETN ;  B8GRD3, RNPA_THISH ;  B1AJP4, RNPA_UREP2 ;
DR   Q9PPN6, RNPA_UREPA ;  B5ZCB8, RNPA_UREU1 ;  A5CVI0, RNPA_VESOH ;
DR   A5F483, RNPA_VIBC3 ;  Q9KVY2, RNPA_VIBCH ;  C3LP79, RNPA_VIBCM ;
DR   Q5E8Z7, RNPA_VIBF1 ;  A7N1E4, RNPA_VIBHB ;  Q87TR4, RNPA_VIBPA ;
DR   Q8DDI3, RNPA_VIBVU ;  Q7MQK4, RNPA_VIBVY ;  Q8PEH6, RNPA_XANAC ;
DR   Q3BLZ6, RNPA_XANC5 ;  Q4UNK7, RNPA_XANC8 ;  B0RMM7, RNPA_XANCB ;
DR   Q8P337, RNPA_XANCP ;  Q2NX51, RNPA_XANOM ;  Q9P9U0, RNPA_XYLFA ;
DR   Q879S2, RNPA_XYLFT ;  A1JT84, RNPA_YERE8 ;  A7FPB9, RNPA_YERP3 ;
DR   Q1C0B6, RNPA_YERPA ;  Q8Z9U4, RNPA_YERPE ;  Q1CCJ6, RNPA_YERPN ;
DR   A4TSL3, RNPA_YERPP ;  Q663S9, RNPA_YERPS ;  Q02773, RPM2_YEAST ;
DR   O95059, RPP14_HUMAN;  Q9CQH8, RPP14_MOUSE;  Q5RB79, RPP14_PONAB;
DR   P38786, RPP1_YEAST ;  Q9H633, RPP21_HUMAN;  Q5TM57, RPP21_MACMU;
DR   Q8R040, RPP21_MOUSE;  Q9BUL9, RPP25_HUMAN;  Q91WE3, RPP25_MOUSE;
DR   Q5PPN2, RPP25_RAT  ;  Q2KIB9, RPP29_BOVIN;  O95707, RPP29_HUMAN;
DR   Q9CR08, RPP29_MOUSE;  Q5R7B0, RPP29_PONAB;  Q5M882, RPP29_RAT  ;
DR   Q3SZ21, RPP30_BOVIN;  Q3ZE13, RPP30_DICDI;  P78346, RPP30_HUMAN;
DR   O88796, RPP30_MOUSE;  Q32LC1, RPP38_BOVIN;  P78345, RPP38_HUMAN;
DR   Q80UU2, RPP38_MOUSE;  A7YWU3, RPP40_BOVIN;  O75818, RPP40_HUMAN;
DR   Q8R1F9, RPP40_MOUSE;  Q5BK64, RPP40_RAT  ;  Q9Y813, RPR2_SCHPO ;
DR   P40571, RPR2_YEAST ;
//
ID   3.1.26.6
DE   Ribonuclease IV.
AN   Endoribonuclease IV.
AN   Poly(A)-specific ribonuclease.
CA   Endonucleolytic cleavage of poly(A) to fragments terminated by 3'-hydroxy
CA   and 5'-phosphate groups.
CC   -!- Forms oligonucleotides with an average chain length of 10.
//
ID   3.1.26.7
DE   Ribonuclease P4.
CA   Endonucleolytic cleavage of RNA, removing 3'-extranucleotides from tRNA
CA   precursor.
//
ID   3.1.26.8
DE   Ribonuclease M5.
AN   5S ribosomal maturation nuclease.
AN   RNase M5.
CA   Endonucleolytic cleavage of RNA, removing 21 and 42 nucleotides,
CA   respectively, from the 5'- and 3'-termini of a 5S-rRNA precursor.
CC   -!- Converts the 5S-rRNA precursor from Bacillus subtilis into 5S-rRNA,
CC       with 5'-phosphate and 3'-hydroxy groups.
//
ID   3.1.26.9
DE   Ribonuclease (poly-(U)-specific).
CA   Endonucleolytic cleavage of poly(U) to fragments terminated by 3'-hydroxy
CA   and 5'-phosphate groups.
CC   -!- Forms oligonucleotides with chain length 6-12.
//
ID   3.1.26.10
DE   Ribonuclease IX.
CA   Endonucleolytic cleavage of poly(U) or poly(C) to fragments terminated by
CA   3'-hydroxy and 5'-phosphate groups.
CC   -!- Acts on poly(U) and poly(C), with a higher affinity for poly(C),
CC       but does not act on poly(A) or poly(G).
//
ID   3.1.26.11
DE   Ribonuclease Z.
AN   3 tRNase.
AN   RNase Z.
AN   tRNA 3 endonuclease.
AN   tRNase Z.
CA   Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA
CA   precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at
CA   the tRNA terminus and a 5'-phosphoryl group is left at the trailer
CA   molecule.
CC   -!- No cofactor requirements.
DR   Q29RY4, RNZ1_BOVIN ;  Q9H777, RNZ1_HUMAN ;  Q8VEB6, RNZ1_MOUSE ;
DR   Q10155, RNZ1_SCHPO ;  Q9GL73, RNZ2_GORGO ;  Q9BQ52, RNZ2_HUMAN ;
DR   Q8HY87, RNZ2_MACFA ;  Q80Y81, RNZ2_MOUSE ;  Q9GL72, RNZ2_PANTR ;
DR   Q8CGS5, RNZ2_RAT   ;  P87168, RNZ2_SCHPO ;  Q8L633, RNZC_ARATH ;
DR   Q8LGU7, RNZN_ARATH ;  P60193, RNZN_WHEAT ;  B0CE23, RNZ_ACAM1  ;
DR   Q9YAV8, RNZ_AERPE  ;  A8MGK0, RNZ_ALKOO  ;  B7GHJ4, RNZ_ANOFW  ;
DR   O29323, RNZ_ARCFU  ;  B6YQ90, RNZ_AZOPC  ;  A7Z6F0, RNZ_BACA2  ;
DR   C3P7S4, RNZ_BACAA  ;  C3LJR8, RNZ_BACAC  ;  A0RID9, RNZ_BACAH  ;
DR   Q81M88, RNZ_BACAN  ;  B7JLZ5, RNZ_BACC0  ;  Q731F6, RNZ_BACC1  ;
DR   B7IWQ5, RNZ_BACC2  ;  C1ER14, RNZ_BACC3  ;  B7HB12, RNZ_BACC4  ;
DR   B7HNQ7, RNZ_BACC7  ;  A7GSG2, RNZ_BACCN  ;  B9IXD7, RNZ_BACCQ  ;
DR   Q818V3, RNZ_BACCR  ;  Q635E2, RNZ_BACCZ  ;  Q5LGN7, RNZ_BACFN  ;
DR   Q64XI2, RNZ_BACFR  ;  Q9KC61, RNZ_BACHD  ;  Q6HE20, RNZ_BACHK  ;
DR   Q65HN6, RNZ_BACLD  ;  Q5WGC3, RNZ_BACSK  ;  P54548, RNZ_BACSU  ;
DR   Q89ZN1, RNZ_BACTN  ;  A6L3H3, RNZ_BACV8  ;  A9VG79, RNZ_BACWK  ;
DR   Q0SMA2, RNZ_BORAP  ;  O51696, RNZ_BORBU  ;  B7J0K1, RNZ_BORBZ  ;
DR   B5RMU7, RNZ_BORDL  ;  Q660C0, RNZ_BORGA  ;  B2S197, RNZ_BORHD  ;
DR   B5RQ92, RNZ_BORRA  ;  A1R0H8, RNZ_BORT9  ;  Q89NF8, RNZ_BRAJA  ;
DR   A4YN80, RNZ_BRASO  ;  C0ZBP8, RNZ_BREBN  ;  O44476, RNZ_CAEEL  ;
DR   A0RYQ9, RNZ_CENSY  ;  Q5L6G2, RNZ_CHLAB  ;  Q823T8, RNZ_CHLCV  ;
DR   Q253T0, RNZ_CHLFF  ;  Q9PK48, RNZ_CHLMU  ;  Q9Z9F6, RNZ_CHLPN  ;
DR   B0B7R5, RNZ_CHLT2  ;  Q3KM12, RNZ_CHLTA  ;  B0BBY0, RNZ_CHLTB  ;
DR   O84350, RNZ_CHLTR  ;  Q97IQ6, RNZ_CLOAB  ;  A6LU82, RNZ_CLOB8  ;
DR   B2V377, RNZ_CLOBA  ;  B2TN28, RNZ_CLOBB  ;  Q182M7, RNZ_CLOD6  ;
DR   B9E3V3, RNZ_CLOK1  ;  A5MZX7, RNZ_CLOK5  ;  A0Q1D1, RNZ_CLONN  ;
DR   Q0TQN4, RNZ_CLOP1  ;  Q8XKN1, RNZ_CLOPE  ;  A9KSU3, RNZ_CLOPH  ;
DR   Q0ST77, RNZ_CLOPS  ;  Q892B5, RNZ_CLOTE  ;  B1WQW1, RNZ_CYAA5  ;
DR   B8HP81, RNZ_CYAP4  ;  B7K762, RNZ_CYAP7  ;  B7K1N1, RNZ_CYAP8  ;
DR   Q11TT4, RNZ_CYTH3  ;  Q9RXP0, RNZ_DEIRA  ;  Q8MKW7, RNZ_DROME  ;
DR   Q834G2, RNZ_ENTFA  ;  C4Z309, RNZ_EUBE2  ;  C4ZFN9, RNZ_EUBR3  ;
DR   B1YLU8, RNZ_EXIS2  ;  C4L3C2, RNZ_EXISA  ;  C1AAD9, RNZ_GEMAT  ;
DR   Q5KXG8, RNZ_GEOKA  ;  C5D428, RNZ_GEOSW  ;  Q7NDW3, RNZ_GLOVI  ;
DR   B9LQT0, RNZ_HALLT  ;  Q5UZJ9, RNZ_HALMA  ;  B0R7E2, RNZ_HALS3  ;
DR   Q9HN60, RNZ_HALSA  ;  D4GZ88, RNZ_HALVD  ;  A8ABB4, RNZ_IGNH4  ;
DR   A6WFU4, RNZ_KINRD  ;  Q5FKH3, RNZ_LACAC  ;  Q03QP5, RNZ_LACBA  ;
DR   Q039J0, RNZ_LACC3  ;  B3WE54, RNZ_LACCB  ;  Q1GAM2, RNZ_LACDA  ;
DR   Q04B09, RNZ_LACDB  ;  B2GBD1, RNZ_LACF3  ;  Q043V9, RNZ_LACGA  ;
DR   A8YV16, RNZ_LACH4  ;  Q74JN5, RNZ_LACJO  ;  Q9CHT8, RNZ_LACLA  ;
DR   A2RIV7, RNZ_LACLM  ;  Q031A3, RNZ_LACLS  ;  Q88VG6, RNZ_LACPL  ;
DR   A5VJA0, RNZ_LACRD  ;  B2G6S0, RNZ_LACRJ  ;  Q1WT50, RNZ_LACS1  ;
DR   Q38WT6, RNZ_LACSS  ;  B1MZQ4, RNZ_LEUCK  ;  Q03W55, RNZ_LEUMM  ;
DR   Q92A38, RNZ_LISIN  ;  C1KWS1, RNZ_LISMC  ;  Q71Y44, RNZ_LISMF  ;
DR   B8DBV5, RNZ_LISMH  ;  Q8Y5S8, RNZ_LISMO  ;  A0AK82, RNZ_LISW6  ;
DR   B9E6P2, RNZ_MACCJ  ;  A1U2M9, RNZ_MARAV  ;  A6UUY8, RNZ_META3  ;
DR   Q8TLK5, RNZ_METAC  ;  Q58897, RNZ_METJA  ;  Q8TWK0, RNZ_METKA  ;
DR   A4FXT9, RNZ_METM5  ;  A9AB37, RNZ_METM6  ;  A6VFJ7, RNZ_METM7  ;
DR   Q8Q032, RNZ_METMA  ;  Q6LYT2, RNZ_METMP  ;  A4YHP1, RNZ_METS5  ;
DR   O27859, RNZ_METTH  ;  A6UN58, RNZ_METVS  ;  B0JGG3, RNZ_MICAN  ;
DR   A0QDL1, RNZ_MYCA1  ;  Q7TYN1, RNZ_MYCBO  ;  A1KL99, RNZ_MYCBP  ;
DR   C1AQX2, RNZ_MYCBT  ;  A4T2G4, RNZ_MYCGI  ;  Q49744, RNZ_MYCLE  ;
DR   B2HMC3, RNZ_MYCMM  ;  Q73XT9, RNZ_MYCPA  ;  A3Q2B8, RNZ_MYCSJ  ;
DR   A1UIW4, RNZ_MYCSK  ;  Q1B671, RNZ_MYCSS  ;  A5U5A1, RNZ_MYCTA  ;
DR   P71736, RNZ_MYCTU  ;  A0PTY0, RNZ_MYCUA  ;  Q1DEJ2, RNZ_MYXXD  ;
DR   Q74MH2, RNZ_NANEQ  ;  Q3IRM5, RNZ_NATPD  ;  A9A3X2, RNZ_NITMS  ;
DR   Q5YQ00, RNZ_NOCFA  ;  B2J3C7, RNZ_NOSP7  ;  Q8YLZ0, RNZ_NOSS1  ;
DR   Q8EQ58, RNZ_OCEIH  ;  Q04EZ9, RNZ_OENOB  ;  A6LFA6, RNZ_PARD8  ;
DR   Q6ME16, RNZ_PARUW  ;  Q03F36, RNZ_PEDPA  ;  Q6KZJ4, RNZ_PICTO  ;
DR   B2RIU4, RNZ_PORG3  ;  Q51834, RNZ_PORGI  ;  A3PEI3, RNZ_PROM0  ;
DR   A2C4C2, RNZ_PROM1  ;  A8G6G0, RNZ_PROM2  ;  A2C725, RNZ_PROM3  ;
DR   A2BY56, RNZ_PROM5  ;  Q319D8, RNZ_PROM9  ;  Q7VAN0, RNZ_PROMA  ;
DR   Q7V5W1, RNZ_PROMM  ;  Q7V0B9, RNZ_PROMP  ;  A2BSS2, RNZ_PROMS  ;
DR   Q46JB7, RNZ_PROMT  ;  Q1IA50, RNZ_PSEE4  ;  A5W1E8, RNZ_PSEP1  ;
DR   B0KMS1, RNZ_PSEPG  ;  Q88FQ4, RNZ_PSEPK  ;  B1J6H3, RNZ_PSEPW  ;
DR   Q9UZP4, RNZ_PYRAB  ;  Q8ZTJ7, RNZ_PYRAE  ;  A4WKM8, RNZ_PYRAR  ;
DR   A3MV61, RNZ_PYRCJ  ;  Q8U182, RNZ_PYRFU  ;  O58883, RNZ_PYRHO  ;
DR   A1RRK1, RNZ_PYRIL  ;  Q5JE70, RNZ_PYRKO  ;  B6IRV8, RNZ_RHOCS  ;
DR   A8M3K2, RNZ_SALAI  ;  Q2S0L2, RNZ_SALRD  ;  A7X2M2, RNZ_STAA1  ;
DR   A6U1X3, RNZ_STAA2  ;  Q2FGM9, RNZ_STAA3  ;  Q2FY67, RNZ_STAA8  ;
DR   A5IT32, RNZ_STAA9  ;  Q2YYA2, RNZ_STAAB  ;  Q5HFR8, RNZ_STAAC  ;
DR   A6QH51, RNZ_STAAE  ;  P60196, RNZ_STAAM  ;  P60197, RNZ_STAAN  ;
DR   Q6GGJ4, RNZ_STAAR  ;  Q6G960, RNZ_STAAS  ;  A8Z2D7, RNZ_STAAT  ;
DR   Q8NWE6, RNZ_STAAW  ;  B9DNT1, RNZ_STACT  ;  Q5HP47, RNZ_STAEQ  ;
DR   Q8CSG7, RNZ_STAES  ;  Q4L6K4, RNZ_STAHJ  ;  Q49XV1, RNZ_STAS1  ;
DR   Q3K0P4, RNZ_STRA1  ;  Q8E4W1, RNZ_STRA3  ;  Q8DZ99, RNZ_STRA5  ;
DR   Q82BX8, RNZ_STRAW  ;  Q9RDE4, RNZ_STRCO  ;  C0MAM9, RNZ_STRE4  ;
DR   B4U3M1, RNZ_STREM  ;  A8AWX4, RNZ_STRGC  ;  B1VY42, RNZ_STRGG  ;
DR   Q8DT90, RNZ_STRMU  ;  P60199, RNZ_STRP1  ;  Q04LL3, RNZ_STRP2  ;
DR   P0DF22, RNZ_STRP3  ;  B5E2R6, RNZ_STRP4  ;  Q5XCH7, RNZ_STRP6  ;
DR   C1C636, RNZ_STRP7  ;  Q8P1A6, RNZ_STRP8  ;  Q1JC59, RNZ_STRPB  ;
DR   Q1JM42, RNZ_STRPC  ;  Q1JH87, RNZ_STRPD  ;  Q1J705, RNZ_STRPF  ;
DR   A2REY2, RNZ_STRPG  ;  B1IAL2, RNZ_STRPI  ;  B8ZMQ6, RNZ_STRPJ  ;
DR   Q48TY8, RNZ_STRPM  ;  Q97RW2, RNZ_STRPN  ;  P0DF23, RNZ_STRPQ  ;
DR   B2IMY3, RNZ_STRPS  ;  B5XL36, RNZ_STRPZ  ;  Q8DQN1, RNZ_STRR6  ;
DR   A4W299, RNZ_STRS2  ;  C0MDJ9, RNZ_STRS7  ;  A3CNR9, RNZ_STRSV  ;
DR   A4VVZ0, RNZ_STRSY  ;  Q5LZD1, RNZ_STRT1  ;  Q5M3Y3, RNZ_STRT2  ;
DR   Q03K89, RNZ_STRTD  ;  B9DUP5, RNZ_STRU0  ;  C1CD41, RNZ_STRZJ  ;
DR   C1CJE0, RNZ_STRZP  ;  C1CQF2, RNZ_STRZT  ;  Q4J9A4, RNZ_SULAC  ;
DR   C3N554, RNZ_SULIA  ;  C4KGQ7, RNZ_SULIK  ;  C3MPH2, RNZ_SULIL  ;
DR   C3MYG0, RNZ_SULIM  ;  C3NHZ9, RNZ_SULIN  ;  C3NDQ2, RNZ_SULIY  ;
DR   Q97Z88, RNZ_SULSO  ;  Q973F1, RNZ_SULTO  ;  B1XN66, RNZ_SYNP2  ;
DR   A5GN87, RNZ_SYNPW  ;  Q7U8S4, RNZ_SYNPX  ;  Q0I7X5, RNZ_SYNS3  ;
DR   Q3AZH7, RNZ_SYNS9  ;  Q3AHP8, RNZ_SYNSC  ;  Q55132, RNZ_SYNY3  ;
DR   Q9HJ19, RNZ_THEAC  ;  Q8DKE4, RNZ_THEEB  ;  Q47PQ7, RNZ_THEFY  ;
DR   C5A5S2, RNZ_THEGJ  ;  B1YAJ2, RNZ_THENV  ;  B6YT50, RNZ_THEON  ;
DR   B9KYQ3, RNZ_THERP  ;  C6A2P3, RNZ_THESM  ;  Q979A8, RNZ_THEVO  ;
DR   Q73LB4, RNZ_TREDE  ;  O07896, RNZ_TREPA  ;  B2S457, RNZ_TREPS  ;
DR   Q118J2, RNZ_TRIEI  ;  P36159, RNZ_YEAST  ;
//
ID   3.1.26.12
DE   Ribonuclease E.
AN   Endoribonuclease E.
AN   RNase E.
CA   Endonucleolytic cleavage of single-stranded RNA in A- and U-rich regions.
CC   -!- RNase E is a bacterial ribonuclease that plays a role in the
CC       processing of ribosomal RNA (9S to 5S rRNA), the chemical degradation
CC       of bulk cellular RNA, the decay of specific regulatory, messenger and
CC       structural RNAs and the control of plasmid DNA replication.
CC   -!- The enzyme binds to monophosphorylated 5' ends of substrates but
CC       exhibits sequential cleavages in the 3' to 5' direction.
CC   -!- 2'-O-Methyl nucleotide substitutions at RNase E binding sites do not
CC       prevent binding but do prevent cleavage of non-modified target
CC       sequences 5' to that locus.
CC   -!- In Escherichia coli, the enzyme is found in the RNA degradosome.
CC   -!- The C-terminal half of the protein contains binding sites for the
CC       three other major degradosomal components, the DEAD-box RNA helicase
CC       Rh1B, EC 4.1.1.11 and EC 2.7.7.8.
CC   -!- Formerly EC 3.1.26.n1.
DR   P57429, RNE_BUCAI  ;  Q8K9J9, RNE_BUCAP  ;  Q89AH3, RNE_BUCBP  ;
DR   P21513, RNE_ECOLI  ;  O78453, RNE_GUITH  ;  P44443, RNE_HAEIN  ;
DR   Q9TL10, RNE_NEPOL  ;  P51211, RNE_PORPU  ;  Q1XDS6, RNE_PORYE  ;
DR   P72656, RNE_SYNY3  ;
//
ID   3.1.26.13
DE   Retroviral ribonuclease H.
CA   Endohydrolysis of RNA in RNA/DNA hybrids. Three different cleavage modes:
CA   1. sequence-specific internal cleavage of RNA. Human immunodeficiency
CA   virus type 1 and Moloney murine leukemia virus enzymes prefer to cleave
CA   the RNA strand one nucleotide away from the RNA-DNA junction. 2. RNA
CA   5'-end directed cleavage 13-19 nucleotides from the RNA end. 3. DNA
CA   3'-end directed cleavage 15-20 nucleotides away from the primer terminus.
CC   -!- Retroviral reverse transcriptase is a multifunctional enzyme
CC       responsible for viral replication.
CC   -!- To perform this task the enzyme combines two distinct activities.
CC   -!- The polymerase domain (EC 2.7.7.49) occupies the N-terminal two-
CC       thirds of the reverse transcriptase whereas the ribonuclease H domain
CC       comprises the C-terminal remaining one-third.
CC   -!- The RNase H domain of Moloney murine leukemia virus and Human
CC       immunodeficiency virus display two metal binding sites.
DR   P19560, POL_BIV29  ;  P33459, POL_CAEVC  ;  P11204, POL_EIAV9  ;
DR   P32542, POL_EIAVC  ;  P03371, POL_EIAVY  ;  P16088, POL_FIVPE  ;
DR   P19028, POL_FIVSD  ;  P31822, POL_FIVT2  ;  O93215, POL_HV190  ;
DR   O12158, POL_HV192  ;  O89290, POL_HV193  ;  Q9QBY3, POL_HV196  ;
DR   Q9QBZ9, POL_HV197  ;  O41798, POL_HV19N  ;  P03369, POL_HV1A2  ;
DR   Q77373, POL_HV1AN  ;  P03366, POL_HV1B1  ;  P04587, POL_HV1B5  ;
DR   Q73368, POL_HV1B9  ;  P03367, POL_HV1BR  ;  P04589, POL_HV1EL  ;
DR   Q75002, POL_HV1ET  ;  P04585, POL_HV1H2  ;  P20875, POL_HV1JR  ;
DR   P0C6F2, POL_HV1LW  ;  Q9QBZ1, POL_HV1M2  ;  P04588, POL_HV1MA  ;
DR   P05961, POL_HV1MN  ;  Q9QBZ5, POL_HV1MP  ;  Q79666, POL_HV1MV  ;
DR   P12497, POL_HV1N5  ;  P18802, POL_HV1ND  ;  P20892, POL_HV1OY  ;
DR   P05959, POL_HV1RH  ;  Q9WC54, POL_HV1S2  ;  Q9WC63, POL_HV1S9  ;
DR   O89940, POL_HV1SE  ;  P24740, POL_HV1U4  ;  Q9Q720, POL_HV1V9  ;
DR   Q9QSR3, POL_HV1VI  ;  P35963, POL_HV1Y2  ;  Q9IDV9, POL_HV1YB  ;
DR   O91080, POL_HV1YF  ;  P12499, POL_HV1Z2  ;  P18096, POL_HV2BE  ;
DR   P24107, POL_HV2CA  ;  P17757, POL_HV2D1  ;  P15833, POL_HV2D2  ;
DR   Q89928, POL_HV2EH  ;  P18042, POL_HV2G1  ;  Q74120, POL_HV2KR  ;
DR   P05962, POL_HV2NZ  ;  P04584, POL_HV2RO  ;  P12451, POL_HV2SB  ;
DR   P20876, POL_HV2ST  ;  Q76634, POL_HV2UC  ;  Q82851, POL_JEMBR  ;
DR   P16901, POL_OMVVS  ;  P17283, POL_SIVCZ  ;  Q1A249, POL_SIVEK  ;
DR   Q02836, POL_SIVG1  ;  P22382, POL_SIVGB  ;  P05896, POL_SIVM1  ;
DR   Q1A267, POL_SIVMB  ;  P05897, POL_SIVMK  ;  P12502, POL_SIVS4  ;
DR   P19505, POL_SIVSP  ;  Q8AII1, POL_SIVTN  ;  P27973, POL_SIVV1  ;
DR   P12500, POL_SIVV2  ;  P12501, POL_SIVV3  ;  P27980, POL_SIVVG  ;
DR   P05895, POL_SIVVT  ;  P03370, POL_VILV   ;  P23426, POL_VILV1  ;
DR   P23427, POL_VILV2  ;  P35956, POL_VILVK  ;
//
ID   3.1.26.n1
DE   Transferred entry: 3.1.26.12.
//
ID   3.1.27.1
DE   Ribonuclease T(2).
AN   Ribonuclease II.
AN   Ribonuclease T2.
CA   Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and
CA   3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.
CC   -!- Formerly EC 2.7.7.17 and EC 3.1.4.23.
PR   PROSITE; PDOC00459;
DR   Q7M438, RNDI_DICDI ;  P81296, RNL2_LENED ;  P80022, RNLE_SOLLC ;
DR   P80196, RNLX_SOLLC ;  P23540, RNMC_MOMCH ;  P19791, RNM_ASPSA  ;
DR   P08056, RNRH_RHINI ;  Q7SID5, RNS11_NICAL;  P42813, RNS1_ARATH ;
DR   O80322, RNS1_PYRPY ;  Q38716, RNS2_ANTHI ;  P42814, RNS2_ARATH ;
DR   P04007, RNS2_NICAL ;  Q40965, RNS2_PYRPY ;  Q01796, RNS2_SOLTU ;
DR   P42815, RNS3_ARATH ;  Q40875, RNS3_PETHY ;  O80323, RNS3_PYRPY ;
DR   Q38717, RNS4_ANTHI ;  Q40966, RNS4_PYRPY ;  P93460, RNS5_PYRPY ;
DR   Q40379, RNS6_NICAL ;  O80324, RNS6_PYRPY ;  Q40381, RNS7_NICAL ;
DR   O80325, RNS7_PYRPY ;  P10281, RNT2_ASPOR ;  P24657, RNTR_TRIVI ;
DR   Q5AK94, RNY1A_CANAL;  Q5AKB1, RNY1B_CANAL;  Q75BW5, RNY1_ASHGO ;
DR   Q4WXZ5, RNY1_ASPFU ;  Q6FP42, RNY1_CANGA ;  Q6BHB1, RNY1_DEBHA ;
DR   Q5B3K6, RNY1_EMENI ;  Q6CRT6, RNY1_KLULA ;  Q6CAV7, RNY1_YARLI ;
DR   Q02933, RNY1_YEAST ;
//
ID   3.1.27.2
DE   Bacillus subtilis ribonuclease.
CA   Endonucleolytic cleavage to 2',3'-cyclic nucleotides.
CC   -!- Similar enzymes: Azotobacter agilis RNase, Proteus mirabilis RNase.
//
ID   3.1.27.3
DE   Ribonuclease T(1).
AN   Aspergillus oryzae ribonuclease.
AN   Guanyloribonuclease.
AN   Ribonuclease T1.
AN   RNase N1.
AN   RNase N2.
CA   Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and
CA   3'-phosphooligonucleotides ending in G-P with 2',3'-cyclic phosphate
CA   intermediates.
CC   -!- Formerly EC 2.7.7.26 and EC 3.1.4.8.
DR   Q7M515, RNA1_ASPPL ;  P00652, RNC2_ASPCL ;  P16411, RNF1_GIBBA ;
DR   P10282, RNF1_GIBFU ;  P16412, RNF2_GIBBA ;  P00653, RNMS_ASPSA ;
DR   P09646, RNN1_NEUCR ;  P07446, RNPB_PENBR ;  P09647, RNPC_PENCH ;
DR   P81762, RNPO_PLEOS ;  P30289, RNS3_STRAU ;  P05798, RNSA_STRAU ;
DR   P00650, RNST_SACER ;  P00651, RNT1_ASPOR ;  P26875, RNT1_TRIHA ;
DR   P07736, RNU1_USTSP ;
//
ID   3.1.27.4
DE   Ribonuclease U(2).
AN   Ribonuclease U2.
CA   Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and
CA   3'-phosphooligonucleotides ending in A-P or G-P with 2',3'-cyclic
CA   phosphate intermediates.
DR   P00654, RNU2_USTSP ;
//
ID   3.1.27.5
DE   Pancreatic ribonuclease.
AN   Pancreatic RNase.
AN   Ribonuclease I.
AN   RNase.
AN   RNase A.
AN   RNase I.
CA   Endonucleolytic cleavage to nucleoside 3'-phosphates and
CA   3'-phosphooligonucleotides ending in Cp or Up with 2',3'-cyclic phosphate
CA   intermediates.
CC   -!- Similar enzymes: venom RNase, Thiobacillus thioparus RNase, Xenopus
CC       laevis RNase, Rhizopus oligosporus RNase, ribonuclease M.
CC   -!- Formerly EC 2.7.7.16 and EC 3.1.4.22.
PR   PROSITE; PDOC00118;
DR   Q9WTT5, RNAS1_ACOCA;  P07847, RNAS1_AEPME;  Q9WUR3, RNAS1_AKOJE;
DR   P00667, RNAS1_ALCAA;  P00668, RNAS1_ANTAM;  Q8SQ06, RNAS1_ATEGE;
DR   P87351, RNAS1_AXIPR;  P00673, RNAS1_BALAC;  P61824, RNAS1_BISBI;
DR   P07849, RNAS1_BOSTR;  P61823, RNAS1_BOVIN;  P00657, RNAS1_BUBBU;
DR   P67929, RNAS1_CAMBA;  P67928, RNAS1_CAMDR;  P00664, RNAS1_CAPCA;
DR   P67926, RNAS1_CAPHI;  P00663, RNAS1_CEREL;  P84844, RNAS1_CHEMY;
DR   P04061, RNAS1_CHESE;  P00675, RNAS1_CHICH;  Q9WUV3, RNAS1_CHINI;
DR   P61821, RNAS1_CHLAE;  P00685, RNAS1_CHOHO;  P00660, RNAS1_CONTA;
DR   P24717, RNAS1_CRIGR;  P00665, RNAS1_DAMDA;  P00659, RNAS1_DAMKO;
DR   P00680, RNAS1_GALMU;  P07848, RNAS1_GAZTH;  Q9WUS2, RNAS1_GERNI;
DR   P00662, RNAS1_GIRCA;  Q9WUS1, RNAS1_GLIGL;  Q8SQ13, RNAS1_GORGO;
DR   P00672, RNAS1_HIPAM;  P00674, RNAS1_HORSE;  P07998, RNAS1_HUMAN;
DR   P00677, RNAS1_HYDHY;  P04060, RNAS1_HYSCR;  P80287, RNAS1_IGUIG;
DR   Q8SQ05, RNAS1_LAGLA;  Q8SQ04, RNAS1_LEMCA;  Q9WUS3, RNAS1_LEOED;
DR   Q8SPN5, RNAS1_MACMU;  P00686, RNAS1_MACRU;  P00682, RNAS1_MESAU;
DR   P61822, RNAS1_MIOTA;  P00683, RNAS1_MOUSE;  Q9QYX3, RNAS1_MUSPA;
DR   Q9QYX2, RNAS1_MUSSA;  P00676, RNAS1_MYOCO;  Q9WUR4, RNAS1_MYOGA;
DR   Q9WUV4, RNAS1_NIVCR;  Q8SQ11, RNAS1_NOMLE;  P19640, RNAS1_ODOVI;
DR   P00681, RNAS1_ONDZI;  Q29606, RNAS1_ORYLE;  Q8SQ14, RNAS1_PANTR;
DR   Q8SQ09, RNAS1_PAPHA;  Q9WUV5, RNAS1_PERLE;  P00671, RNAS1_PIG  ;
DR   Q8SQ12, RNAS1_PONPY;  P04059, RNAS1_PROGU;  Q8SPN4, RNAS1_PYGNE;
DR   P00666, RNAS1_RANTA;  Q8SQ07, RNAS1_SAGOE;  Q8SQ08, RNAS1_SAISC;
DR   P19644, RNAS1_SEMEN;  P67927, RNAS1_SHEEP;  P16414, RNAS1_SPAEH;
DR   Q8VD83, RNAS1_SUNME;  Q9WUX4, RNAS1_TATKG;  P00658, RNAS1_TRAOR;
DR   Q9WUX6, RNAS1_URARU;  O18937, RNAS2_AOTTR;  Q8SPY2, RNAS2_CALJA;
DR   Q8SPY6, RNAS2_CHLAE;  P47782, RNAS2_GORGO;  P10153, RNAS2_HUMAN;
DR   P47783, RNAS2_MACFA;  Q8SPY5, RNAS2_MACNE;  O35291, RNAS2_MOUSE;
DR   Q8SPY8, RNAS2_NOMLE;  P47785, RNAS2_PANTR;  Q8SPY7, RNAS2_PAPHA;
DR   P80551, RNAS2_PIG  ;  P47784, RNAS2_PONPY;  Q8SPY3, RNAS2_SAGLB;
DR   P47786, RNAS2_SAGOE;  Q8SPY4, RNAS2_SAISC;  P14626, RNASL_RANCA;
DR   P15466, RNL1_PIG   ;  P00678, RNS1A_CAVPO;  Q8VD93, RNS1A_RATEX;
DR   Q8VD91, RNS1A_RATFU;  P00679, RNS1B_CAVPO;  Q8SPN3, RNS1B_PYGNE;
DR   P00684, RNS1B_RAT  ;  Q9WUX3, RNS1B_RATEX;  Q8VD84, RNS1B_RATTI;
DR   Q8VD88, RNS1D_RAT  ;  Q8VD92, RNS1D_RATEX;  Q8VD86, RNS1D_RATRT;
DR   Q8VD85, RNS1D_RATTI;  Q8VD89, RNS1G_RAT  ;  Q8VD90, RNS1G_RATFU;
DR   Q8VD87, RNS1G_RATRT;  P00669, RNS_BOVIN  ;  Q29539, RNS_CEPSI  ;
DR   Q29535, RNS_GIRCA  ;  Q29538, RNS_SAITA  ;
//
ID   3.1.27.6
DE   Enterobacter ribonuclease.
CA   Endonucleolytic cleavage to nucleoside 3'-phosphates and
CA   3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.
CC   -!- Preference for cleavage at CpA.
CC   -!- Homopolymers of A, U or G are not hydrolyzed.
PR   PROSITE; PDOC00459;
DR   P21338, RNI_ECOLI  ;
//
ID   3.1.27.7
DE   Ribonuclease F.
AN   RNase F.
CA   Endonucleolytic cleavage of RNA precursor into two, leaving 5'-hydroxy
CA   and 3'-phosphate groups.
CC   -!- Cleavage takes place between a cytosine and an adenine.
//
ID   3.1.27.8
DE   Ribonuclease V.
AN   Endoribonuclease V.
CA   Hydrolysis of poly(A), forming oligoribonucleotides and ultimately
CA   3'-AMP.
CC   -!- Also hydrolyzes poly(U).
//
ID   3.1.27.9
DE   tRNA-intron endonuclease.
AN   tRNA-splicing endonuclease.
CA   Endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxy and
CA   2',3'-cyclic phosphate termini, and specifically removing the intron.
CC   -!- The enzyme catalyzes the final stage in the maturation of tRNA
CC       molecules.
DR   Q9YBF1, ENDA_AERPE ;  O29362, ENDA_ARCFU ;  Q5UYF6, ENDA_HALMA ;
DR   B0R7C0, ENDA_HALS3 ;  Q9HN82, ENDA_HALSA ;  O07118, ENDA_HALVD ;
DR   A2BIW2, ENDA_HYPBU ;  Q8TGX1, ENDA_METAC ;  Q46FK9, ENDA_METBF ;
DR   Q12X51, ENDA_METBU ;  Q58819, ENDA_METJA ;  Q8TGZ7, ENDA_METKA ;
DR   Q8PZI1, ENDA_METMA ;  Q6LY59, ENDA_METMP ;  O07165, ENDA_METTH ;
DR   A6UPD9, ENDA_METVS ;  Q74MP4, ENDA_NANEQ ;  Q3IU70, ENDA_NATPD ;
DR   Q6L1P9, ENDA_PICTO ;  Q9UY33, ENDA_PYRAB ;  Q8ZVI1, ENDA_PYRAE ;
DR   A4WLV3, ENDA_PYRAR ;  Q8U429, ENDA_PYRFU ;  O58033, ENDA_PYRHO ;
DR   A1RSY7, ENDA_PYRIL ;  Q5JHP5, ENDA_PYRKO ;  Q4JAF4, ENDA_SULAC ;
DR   C3N6N2, ENDA_SULIA ;  C4KIA4, ENDA_SULIK ;  C3MQX7, ENDA_SULIL ;
DR   C3MWW5, ENDA_SULIM ;  C3NGJ0, ENDA_SULIN ;  C3N746, ENDA_SULIY ;
DR   Q97ZY3, ENDA_SULSO ;  Q975R3, ENDA_SULTO ;  Q9HIY5, ENDA_THEAC ;
DR   C5A2D9, ENDA_THEGJ ;  B1Y9D1, ENDA_THENV ;  B6YXU4, ENDA_THEON ;
DR   Q97BQ3, ENDA_THEVO ;  Q9M1E8, SEN21_ARATH;  Q9LSS3, SEN22_ARATH;
DR   Q74ZY5, SEN2_ASHGO ;  Q5ZIN2, SEN2_CHICK ;  Q8NCE0, SEN2_HUMAN ;
DR   Q6P7W5, SEN2_MOUSE ;  Q9P6Y2, SEN2_NEUCR ;  Q5Z6B1, SEN2_ORYSJ ;
DR   Q5M954, SEN2_RAT   ;  Q8TFH7, SEN2_SCHPO ;  P16658, SEN2_YEAST ;
DR   Q754T3, SEN34_ASHGO;  Q9BSV6, SEN34_HUMAN;  Q8BMZ5, SEN34_MOUSE;
DR   Q7SAK9, SEN34_NEUCR;  O60156, SEN34_SCHPO;  P39707, SEN34_YEAST;
//
ID   3.1.27.10
DE   rRNA endonuclease.
AN   Alpha-sarcin.
CA   Hydrolysis of the phosphodiester linkage between guanosine and adenosine
CA   residues at one specific position in 28S rRNA from rat ribosomes.
CC   -!- Also acts on bacterial rRNA.
DR   P00655, RNAS_ASPGI ;
//
ID   3.1.30.1
DE   Aspergillus nuclease S(1).
AN   Aspergillus nuclease S1.
AN   Deoxyribonuclease S1.
AN   Endonuclease S1.
AN   Single-stranded-nucleate endonuclease.
CA   Endonucleolytic cleavage to 5'-phosphomononucleotide and
CA   5'-phosphooligonucleotide end-products.
CF   Zinc.
CC   -!- Preference for single-stranded substrate.
CC   -!- Similar enzymes: Neurospora crassa nuclease, mung bean nuclease,
CC       Penicillium citrinum nuclease P1.
CC   -!- Formerly EC 3.1.4.21.
DR   P24289, NUP1_PENCI ;  P24021, NUS1_ASPOR ;
//
ID   3.1.30.2
DE   Serratia marcescens nuclease.
AN   Endonuclease (Serratia marcescens).
CA   Endonucleolytic cleavage to 5'-phosphomononucleotide and
CA   5'-phosphooligonucleotide end-products.
CC   -!- Hydrolyzes double- or single-stranded substrate.
CC   -!- Similar enzymes: silkworm nuclease, potato nuclease, Azotobacter
CC       nuclease.
CC   -!- Formerly EC 3.1.4.9.
PR   PROSITE; PDOC00821;
DR   P13717, NUCA_SERMA ;
//
ID   3.1.31.1
DE   Micrococcal nuclease.
AN   Micrococcal endonuclease.
CA   Endonucleolytic cleavage to nucleoside 3'-phosphates and
CA   3'-phosphooligonucleotide end-products.
CC   -!- Hydrolyzes double- or single-stranded substrate.
CC   -!- Similar enzymes: Chlamydomonas nuclease, spleen phosphodiesterase,
CC       spleen endonuclease.
CC   -!- Formerly EC 3.1.4.7.
PR   PROSITE; PDOC00865;
DR   P29769, NUC_SHIFL  ;  Q5HHM4, NUC_STAAC  ;  Q99VJ0, NUC_STAAM  ;
DR   Q7A6P2, NUC_STAAN  ;  Q6GIK1, NUC_STAAR  ;  Q6GB41, NUC_STAAS  ;
DR   P00644, NUC_STAAU  ;  Q8NXI6, NUC_STAAW  ;  P43270, NUC_STAHY  ;
DR   P43269, NUC_STAIN  ;
//
ID   3.2.1.1
DE   Alpha-amylase.
AN   Glycogenase.
CA   Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in oligosaccharides
CA   and polysaccharides.
CC   -!- Acts on starch, glycogen and related polysaccharides and
CC       oligosaccharides in a random manner; reducing groups are liberated in
CC       the alpha-configuration.
PR   PROSITE; PDOC51166;
DR   Q23834, AM4N_DROAN ;  P53354, AMY1_AEDAE ;  P22630, AMY1_AERHY ;
DR   P86072, AMY1_CAPAA ;  P86084, AMY1_CAPCH ;  P09961, AMY1_DICT6 ;
DR   Q23835, AMY1_DROAN ;  P25718, AMY1_ECOLI ;  P00693, AMY1_HORVU ;
DR   P04745, AMY1_HUMAN ;  Q01117, AMY1_LIPKO ;  P00687, AMY1_MOUSE ;
DR   P17654, AMY1_ORYSJ ;  P21567, AMY1_SACFI ;  P19269, AMY1_SCHOC ;
DR   O74922, AMY1_SCHPO ;  A2YGY2, AMY2A_ORYSI;  Q0D9J1, AMY2A_ORYSJ;
DR   P19961, AMY2B_HUMAN;  P86088, AMY2_CAPCH ;  P14898, AMY2_DICT6 ;
DR   O18345, AMY2_DROAN ;  P26612, AMY2_ECOLI ;  P04063, AMY2_HORVU ;
DR   P26613, AMY2_SALTY ;  Q08806, AMY2_SCHOC ;  Q09840, AMY2_SCHPO ;
DR   P27932, AMY3A_ORYSJ;  P27937, AMY3B_ORYSJ;  P27939, AMY3C_ORYSJ;
DR   P27933, AMY3D_ORYSJ;  P27934, AMY3E_ORYSJ;  P86089, AMY3_CAPCH ;
DR   P14899, AMY3_DICT6 ;  P04747, AMY3_HORVU ;  Q9Y7S9, AMY3_SCHPO ;
DR   P08117, AMY3_WHEAT ;  P86090, AMY4_CAPCH ;  P04748, AMY4_HORVU ;
DR   O42918, AMY4_SCHPO ;  P04749, AMY5_HORVU ;  P04750, AMY6_HORVU ;
DR   P0C1B3, AMYA1_ASPOR;  P0C1B4, AMYA3_ASPOR;  P41131, AMYA_AERHY ;
DR   Q02905, AMYA_ASPAW ;  P56271, AMYA_ASPNG ;  P54215, AMYA_DROMA ;
DR   P08144, AMYA_DROME ;  P83833, AMYA_DROYA ;  Q59006, AMYA_METJA ;
DR   Q9V298, AMYA_PYRAB ;  P49067, AMYA_PYRFU ;  O57932, AMYA_PYRHO ;
DR   P17859, AMYA_VIGMU ;  Q02906, AMYB_ASPAW ;  P81641, AMYB_DROME ;
DR   Q9BN01, AMYB_DROYA ;  P21543, AMYB_PAEPO ;  A2WPU3, AMYC1_ORYSI;
DR   Q0JMV4, AMYC1_ORYSJ;  P04746, AMYP_HUMAN ;  P00688, AMYP_MOUSE ;
DR   P00690, AMYP_PIG   ;  P00689, AMYP_RAT   ;  P83053, AMYP_STRCA ;
DR   O18344, AMYR_DROAN ;  O77011, AMYR_DROAP ;  O77020, AMYR_DROAV ;
DR   O77019, AMYR_DROBA ;  O76284, AMYR_DROBC ;  Q9NJN8, AMYR_DROBP ;
DR   O77021, AMYR_DRODO ;  O77012, AMYR_DROEC ;  Q9NJP0, AMYR_DROEL ;
DR   O76265, AMYR_DROER ;  Q9GQV3, AMYR_DROJA ;  O77013, AMYR_DROKI ;
DR   O76262, AMYR_DROLN ;  O77014, AMYR_DROMA ;  O18408, AMYR_DROME ;
DR   O77015, AMYR_DROOR ;  O77022, AMYR_DROPN ;  O18552, AMYR_DROPS ;
DR   O76261, AMYR_DROSE ;  O77016, AMYR_DROSI ;  O76459, AMYR_DROSR ;
DR   O18420, AMYR_DROSU ;  O76260, AMYR_DROTE ;  O77018, AMYR_DROTK ;
DR   Q9NJN7, AMYR_DROVA ;  O76263, AMYR_DROWI ;  O76264, AMYR_DROYA ;
DR   P30292, AMY_ASPSH  ;  P00692, AMY_BACAM  ;  P08137, AMY_BACCI  ;
DR   P06278, AMY_BACLI  ;  P20845, AMY_BACME  ;  P86331, AMY_BACSP  ;
DR   P00691, AMY_BACSU  ;  P30269, AMY_BUTFI  ;  P86005, AMY_CAPAN  ;
DR   P23671, AMY_CLOAB  ;  P49274, AMY_DERPT  ;  P06279, AMY_GEOSE  ;
DR   P91778, AMY_PECMA  ;  O97396, AMY_PHACE  ;  P29957, AMY_PSEHA  ;
DR   P30270, AMY_STRGR  ;  P08486, AMY_STRHY  ;  Q05884, AMY_STRLI  ;
DR   P09794, AMY_STRLM  ;  P27350, AMY_STRTL  ;  P22998, AMY_STRVL  ;
DR   P56634, AMY_TENMO  ;  P29750, AMY_THECU  ;  P85843, AMY_TITSE  ;
DR   P09107, AMY_TRICA  ;  P38939, APU_THEP3  ;  P36905, APU_THESA  ;
DR   P38536, APU_THETU  ;  P16950, APU_THETY  ;  O14154, MDE5_SCHPO ;
DR   A0R6E0, TRES_MYCS2 ;  O07176, TRES_MYCTU ;
//
ID   3.2.1.2
DE   Beta-amylase.
AN   4-alpha-D-glucan maltohydrolase.
AN   Glycogenase.
AN   Saccharogen amylase.
CA   Hydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides so as
CA   to remove successive maltose units from the non-reducing ends of the
CA   chains.
CC   -!- Acts on starch, glycogen and related polysaccharides and
CC       oligosaccharides producing beta-maltose by an inversion.
PR   PROSITE; PDOC00414;
DR   P36924, AMYB_BACCE ;  P06547, AMYB_BACCI ;  P96513, AMYB_BACFI ;
DR   P82993, AMYB_HORVS ;  P16098, AMYB_HORVU ;  P10537, AMYB_IPOBA ;
DR   P55005, AMYB_MAIZE ;  O22585, AMYB_MEDSA ;  P21543, AMYB_PAEPO ;
DR   P30271, AMYB_SECCE ;  P10538, AMYB_SOYBN ;  P19584, AMYB_THETU ;
DR   O65015, AMYB_TRIRP ;  O64407, AMYB_VIGUN ;  P93594, AMYB_WHEAT ;
DR   Q9LIR6, BAM1_ARATH ;  O65258, BAM2_ARATH ;  O23553, BAM3_ARATH ;
DR   P25853, BAM5_ARATH ;  Q8L762, BAM6_ARATH ;  O80831, BAM7_ARATH ;
DR   Q9FH80, BAM8_ARATH ;
//
ID   3.2.1.3
DE   Glucan 1,4-alpha-glucosidase.
AN   4-alpha-D-glucan glucohydrolase.
AN   Amyloglucosidase.
AN   Exo-1,4-alpha-glucosidase.
AN   Gamma-amylase.
AN   Glucoamylase.
AN   Lysosomal alpha-glucosidase.
CA   Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues
CA   successively from non-reducing ends of the chains with release of beta-D-
CA   glucose.
CC   -!- Most forms of the enzyme can rapidly hydrolyze 1,6-alpha-D-glucosidic
CC       bonds when the next bond in the sequence is 1,4, and some
CC       preparations of this enzyme hydrolyze 1,6- and 1,3-alpha-D-glucosidic
CC       bonds in other polysaccharides.
CC   -!- This entry covers all such enzymes acting on polysaccharides more
CC       rapidly than on oligosaccharides.
CC   -!- EC 3.2.1.20 from mammalian intestine can catalyze similar reactions.
PR   PROSITE; PDOC00120;
PR   PROSITE; PDOC00646;
PR   PROSITE; PDOC51166;
DR   P69327, AMYG_ASPAW ;  P23176, AMYG_ASPKA ;  P69328, AMYG_ASPNG ;
DR   P36914, AMYG_ASPOR ;  P22832, AMYG_ASPSH ;  P42042, AMYG_BLAAD ;
DR   O74254, AMYG_CANAL ;  P29761, AMYG_CLOS0 ;  Q03045, AMYG_HORRE ;
DR   P14804, AMYG_NEUCR ;  P07683, AMYG_RHIOR ;  P08017, AMYG_SACFI ;
DR   P22861, AMYG_SCHOC ;  O60087, AMYG_SCHPO ;  P08019, AMYG_YEAST ;
DR   P26989, AMYH_SACFI ;  P04065, AMYH_YEASX ;  P29760, AMYI_YEASX ;
DR   O43451, MGA_HUMAN  ;
//
ID   3.2.1.4
DE   Cellulase.
AN   Avicelase.
AN   Beta-1,4-endoglucan hydrolase.
AN   Beta-1,4-glucanase.
AN   Carboxymethyl cellulase.
AN   Celludextrinase.
AN   Endo-1,4-beta-D-glucanase.
AN   Endo-1,4-beta-D-glucanohydrolase.
AN   Endo-1,4-beta-glucanase.
AN   Endoglucanase.
CA   Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose,
CA   lichenin and cereal beta-D-glucans.
CC   -!- Will also hydrolyze 1,4-linkages in beta-D-glucans also containing
CC       1,3-linkages.
PR   PROSITE; PDOC00511;
PR   PROSITE; PDOC00563;
PR   PROSITE; PDOC00565;
PR   PROSITE; PDOC00640;
PR   PROSITE; PDOC00877;
PR   PROSITE; PDOC51172;
DR   A1CG87, CELB_ASPCL ;  B0YBX0, CELB_ASPFC ;  B8NW70, CELB_ASPFN ;
DR   Q4WAJ6, CELB_ASPFU ;  Q2TX26, CELB_ASPOR ;  Q0CC84, CELB_ASPTN ;
DR   Q5B7R2, CELB_EMENI ;  A1D932, CELB_NEOFI ;  P40942, CEXY_CLOSR ;
DR   Q5BDU5, EGLA_EMENI ;  B8MW97, EGLB_ASPFN ;  Q96WQ8, EGLB_ASPKA ;
DR   A2QPC3, EGLB_ASPNC ;  O74706, EGLB_ASPNG ;  Q2UPQ4, EGLB_ASPOR ;
DR   Q1HFS8, EGLB_EMENI ;  A1DME8, EGLB_NEOFI ;  A1C4H2, EGLD_ASPCL ;
DR   B0Y9G4, EGLD_ASPFC ;  B8MXJ7, EGLD_ASPFN ;  Q4WBU0, EGLD_ASPFU ;
DR   Q96WQ9, EGLD_ASPKA ;  A2R5N0, EGLD_ASPNC ;  Q2US83, EGLD_ASPOR ;
DR   Q0CEU4, EGLD_ASPTN ;  Q5BCX8, EGLD_EMENI ;  A1DBS6, EGLD_NEOFI ;
DR   Q8LCP6, GUN10_ARATH;  Q84R49, GUN10_ORYSJ;  O48766, GUN11_ARATH;
DR   Q7XTH4, GUN11_ORYSJ;  O64889, GUN12_ARATH;  Q7XUK4, GUN12_ORYSJ;
DR   O64890, GUN13_ARATH;  A2XYW8, GUN13_ORYSI;  Q0J930, GUN13_ORYSJ;
DR   Q8S8Q4, GUN14_ARATH;  P0C1U5, GUN14_ORYSJ;  O80497, GUN15_ARATH;
DR   Q6L4I2, GUN15_ORYSJ;  Q8VYG3, GUN16_ARATH;  Q654U4, GUN16_ORYSJ;
DR   O81416, GUN17_ARATH;  Q652F9, GUN17_ORYSJ;  Q9SZ90, GUN18_ARATH;
DR   Q5Z9P8, GUN18_ORYSJ;  Q8L7I0, GUN19_ARATH;  Q6YXT7, GUN19_ORYSJ;
DR   P54583, GUN1_ACIC1 ;  Q9SRX3, GUN1_ARATH ;  P06566, GUN1_BACS4 ;
DR   P07983, GUN1_BACSU ;  P20847, GUN1_BUTFI ;  P17877, GUN1_CLOJO ;
DR   Q04469, GUN1_CRYFL ;  Q12622, GUN1_HUMGT ;  P56680, GUN1_HUMIN ;
DR   Q5NAT8, GUN1_ORYSJ ;  P05522, GUN1_PERAE ;  P58599, GUN1_RALSO ;
DR   P16216, GUN1_RUMAL ;  P21833, GUN1_SCLSC ;  P33682, GUN1_STRHA ;
DR   Q05156, GUN1_STRRE ;  P13933, GUN1_STRSS ;  Q12714, GUN1_TRILO ;
DR   P07981, GUN1_TRIRE ;  P85218, GUN1_TRIVI ;  P54424, GUN1_USTMA ;
DR   Q9SUS0, GUN20_ARATH;  Q6ZA06, GUN20_ORYSJ;  Q9STW8, GUN21_ARATH;
DR   Q84Q51, GUN21_ORYSJ;  Q9SVJ4, GUN22_ARATH;  Q6H3Z9, GUN22_ORYSJ;
DR   Q8GY58, GUN23_ARATH;  Q69NF5, GUN23_ORYSJ;  Q93YQ7, GUN24_ARATH;
DR   Q69SG5, GUN24_ORYSJ;  Q38890, GUN25_ARATH;  Q9FXI9, GUN2_ARATH ;
DR   P06565, GUN2_BACS4 ;  P10475, GUN2_BACSU ;  P37701, GUN2_CLOJO ;
DR   Q5NAT0, GUN2_ORYSJ ;  P23666, GUN2_PERAE ;  P17974, GUN2_RALSO ;
DR   P21834, GUN2_SCLSC ;  P26222, GUN2_THEFU ;  P07982, GUN2_TRIRE ;
DR   Q2V4L8, GUN3_ARATH ;  P19570, GUN3_BACS4 ;  P23549, GUN3_BACSU ;
DR   P14250, GUN3_FIBSS ;  Q12624, GUN3_HUMIN ;  Q8LQ92, GUN3_ORYSJ ;
DR   O49296, GUN4_ARATH ;  P28622, GUN4_BACS5 ;  Q6Z715, GUN4_ORYSJ ;
DR   Q07940, GUN4_RUMAL ;  P26221, GUN4_THEFU ;  O14405, GUN4_TRIRE ;
DR   Q9M995, GUN5_ARATH ;  O85465, GUN5_BACAG ;  P43316, GUN5_HUMIN ;
DR   Q67UW5, GUN5_ORYSJ ;  Q01786, GUN5_THEFU ;  P43317, GUN5_TRIRE ;
DR   Q42059, GUN6_ARATH ;  P22699, GUN6_DICDI ;  Q7SIG5, GUN6_HUMIN ;
DR   Q6Z2J3, GUN6_ORYSJ ;  O04478, GUN7_ARATH ;  Q6Z5P2, GUN7_ORYSJ ;
DR   Q7Z9M7, GUN7_TRIRE ;  Q9CAC1, GUN8_ARATH ;  Q6K7G9, GUN8_ORYSJ ;
DR   Q9C9H5, GUN9_ARATH ;  P0C1U4, GUN9_ORYSJ ;  Q12679, GUNA_ASPKA ;
DR   Q5YLG1, GUNA_BACPU ;  P22541, GUNA_BUTFI ;  P22534, GUNA_CALSA ;
DR   P07984, GUNA_CELFI ;  P10476, GUNA_CELJU ;  P17901, GUNA_CLOCE ;
DR   P54937, GUNA_CLOLO ;  A3DC29, GUNA_CLOTH ;  P0C2S2, GUNA_CLOTM ;
DR   P23665, GUNA_FIBSU ;  P84194, GUNA_GLOTR ;  P37696, GUNA_GLUHA ;
DR   O08342, GUNA_PAEBA ;  P29719, GUNA_PAELA ;  P23660, GUNA_RUMAL ;
DR   P27035, GUNA_STRLI ;  P26414, GUNA_THEBI ;  P19487, GUNA_XANCP ;
DR   P10474, GUNB_CALSA ;  P26225, GUNB_CELFI ;  P18126, GUNB_CELJU ;
DR   P28621, GUNB_CLOC7 ;  P04956, GUNB_CLOTH ;  P46236, GUNB_FUSOX ;
DR   P84196, GUNB_GLOTR ;  Q12647, GUNB_NEOPA ;  P23550, GUNB_PAELA ;
DR   P23661, GUNB_RUMAL ;  P14090, GUNC_CELFA ;  P27033, GUNC_CELJU ;
DR   P37699, GUNC_CLOCE ;  P23340, GUNC_CLOSF ;  A3DJ77, GUNC_CLOTH ;
DR   P0C2S3, GUNC_CLOTM ;  P46237, GUNC_FUSOX ;  P50400, GUND_CELFI ;
DR   P28623, GUND_CLOC7 ;  P25472, GUND_CLOCE ;  A3DDN1, GUND_CLOTH ;
DR   P0C2S4, GUND_CLOTM ;  P10477, GUNE_CLOTM ;  Q05622, GUNE_RUMFL ;
DR   P37698, GUNF_CLOCE ;  P26224, GUNF_CLOTH ;  P46239, GUNF_FUSOX ;
DR   P37700, GUNG_CLOCE ;  Q05332, GUNG_CLOTH ;  P16218, GUNH_CLOTH ;
DR   Q02934, GUNI_CLOTH ;  P45699, GUNK_FUSOX ;  Q59394, GUNN_ERWCT ;
DR   A3DH67, GUNS_CLOTH ;  P0C2S5, GUNS_CLOTM ;  P16630, GUNS_PECCC ;
DR   Q47096, GUNV_PECCC ;  Q59395, GUNW_PECCC ;  P15329, GUNX_CLOTM ;
DR   P38534, GUNX_PRUPE ;  P27032, GUNY_DICD3 ;  P23659, GUNZ_CLOSR ;
DR   P07103, GUNZ_DICD3 ;  P22669, GUN_ASPAC  ;  P06564, GUN_BACS1  ;
DR   P19424, GUN_BACS6  ;  P29019, GUN_BACSZ  ;  P18336, GUN_CELUD  ;
DR   P15704, GUN_CLOSA  ;  Q8X5L9, GUN_ECO57  ;  P37651, GUN_ECOLI  ;
DR   P82186, GUN_MYTED  ;  P23548, GUN_PAEPO  ;  O97401, GUN_PHACE  ;
DR   P22503, GUN_PHAVU  ;  Q8RSY9, GUN_PSEFS  ;  P23044, GUN_ROBSP  ;
DR   Q8Z289, GUN_SALTI  ;  Q8ZLB7, GUN_SALTY  ;  P81190, GUN_SCHCO  ;
DR   P58935, GUN_XANAC  ;  P22533, MANB_CALSA ;  P84195, XYNA_GLOTR ;
//
ID   3.2.1.5
DE   Deleted entry.
//
ID   3.2.1.6
DE   Endo-1,3(4)-beta-glucanase.
AN   Endo-1,3-beta-glucanase.
AN   Endo-1,4-beta-glucanase.
AN   Laminarinase.
CA   Endohydrolysis of (1->3)- or (1->4)-linkages in beta-D-glucans when the
CA   glucose residue whose reducing group is involved in the linkage to be
CA   hydrolyzed is itself substituted at C-3.
CC   -!- Substrates include laminarin, lichenin and cereal D-glucans.
CC   -!- Different from EC 3.2.1.39 and EC 3.2.1.52.
PR   PROSITE; PDOC00794;
DR   A1C7B5, EGLX_ASPCL ;  B0XTU6, EGLX_ASPFC ;  B8N7S7, EGLX_ASPFN ;
DR   Q4X084, EGLX_ASPFU ;  A2QBQ3, EGLX_ASPNC ;  Q2UIE6, EGLX_ASPOR ;
DR   Q5BAP5, EGLX_EMENI ;  A1DHY9, EGLX_NEOFI ;  Q9UT45, ENG1_SCHPO ;
DR   P53753, ENG1_YEAST ;  Q09850, ENG2_SCHPO ;  Q12168, ENG2_YEAST ;
//
ID   3.2.1.7
DE   Inulinase.
AN   Inulase.
CA   Endohydrolysis of (2->1)-beta-D-fructosidic linkages in inulin.
PR   PROSITE; PDOC00532;
DR   P28999, INU1_KLUMA ;  O94220, INU2_ASPFI ;
//
ID   3.2.1.8
DE   Endo-1,4-beta-xylanase.
CA   Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
PR   PROSITE; PDOC00510;
PR   PROSITE; PDOC00565;
PR   PROSITE; PDOC00622;
PR   PROSITE; PDOC51175;
DR   P40942, CEXY_CLOSR ;  P07986, GUX_CELFI  ;  O60206, XLNA_AGABI ;
DR   P83513, XY11A_PSEXY;  Q06562, XYN1_COCCA ;  P40943, XYN1_GEOSE ;
DR   P55334, XYN1_HUMIN ;  P36218, XYN1_TRIRE ;  P45703, XYN2_GEOSE ;
DR   P55335, XYN2_MAGO7 ;  P36217, XYN2_TRIRE ;  P33557, XYN3_ASPKA ;
DR   Q12550, XYN4_ASPNG ;  P23557, XYN4_CALSA ;  A2R4D1, XYN5_ASPNC ;
DR   Q12549, XYN5_ASPNG ;  Q6QJ75, XYN6_ASPNG ;  Q8GJ44, XYNA1_CLOSR;
DR   C6CRV0, XYNA1_PAESJ;  P33558, XYNA2_CLOSR;  O59859, XYNA_ASPAC ;
DR   P55328, XYNA_ASPAW ;  A1CCU0, XYNA_ASPCL ;  B0XXF3, XYNA_ASPFC ;
DR   B8NKE9, XYNA_ASPFN ;  Q4WG11, XYNA_ASPFU ;  P33559, XYNA_ASPKA ;
DR   P55329, XYNA_ASPNG ;  Q9HFA4, XYNA_ASPOR ;  Q0CFS3, XYNA_ASPTN ;
DR   P55331, XYNA_ASPTU ;  P09850, XYNA_BACCI ;  P07528, XYNA_BACHD ;
DR   P49942, XYNA_BACOV ;  P00694, XYNA_BACPU ;  P18429, XYNA_BACSU ;
DR   P23551, XYNA_BUTFI ;  P23556, XYNA_CALSA ;  P40944, XYNA_CALSR ;
DR   P14768, XYNA_CELJU ;  P17137, XYNA_CLOSA ;  P07529, XYNA_CRYAL ;
DR   P80718, XYNA_DICB4 ;  Q12603, XYNA_DICTH ;  P55332, XYNA_EMENI ;
DR   P45705, XYNA_GEOSE ;  P84195, XYNA_GLOTR ;  A1DJ52, XYNA_NEOFI ;
DR   P29127, XYNA_NEOPA ;  P81536, XYNA_PAEVA ;  P29417, XYNA_PENCH ;
DR   P56588, XYNA_PENSI ;  Q12667, XYNA_PIRSP ;  P48789, XYNA_PRERU ;
DR   P29126, XYNA_RUMFL ;  P35809, XYNA_SCHCO ;  P26514, XYNA_STRLI ;
DR   P23360, XYNA_THEAU ;  O43097, XYNA_THELA ;  Q60037, XYNA_THEMA ;
DR   Q60042, XYNA_THENE ;  P36917, XYNA_THESA ;  A1CU59, XYNB_ASPCL ;
DR   B0Y8Q8, XYNB_ASPFC ;  B8NJ86, XYNB_ASPFN ;  Q4WLV2, XYNB_ASPFU ;
DR   P48824, XYNB_ASPKA ;  A2Q7I0, XYNB_ASPNC ;  P55330, XYNB_ASPNG ;
DR   P87037, XYNB_ASPOR ;  P26223, XYNB_BUTFI ;  P23030, XYNB_CELJU ;
DR   P80717, XYNB_DICB4 ;  P55333, XYNB_EMENI ;  A1DNU5, XYNB_NEOFI ;
DR   O69231, XYNB_PAEBA ;  P26515, XYNB_STRLI ;  Q60041, XYNB_THENE ;
DR   A1CHQ0, XYNC_ASPCL ;  B0Y6E0, XYNC_ASPFC ;  Q0H904, XYNC_ASPFU ;
DR   A2QFV7, XYNC_ASPNC ;  C5J411, XYNC_ASPNG ;  Q4JHP5, XYNC_ASPTE ;
DR   Q0CBM8, XYNC_ASPTN ;  Q00177, XYNC_EMENI ;  P35811, XYNC_FIBSS ;
DR   A1CX14, XYNC_NEOFI ;  O69230, XYNC_PAEBA ;  Q9RI72, XYNC_STRCO ;
DR   P26220, XYNC_STRLI ;  P54865, XYND_CELFI ;  Q53317, XYND_RUMFL ;
DR   B8NER4, XYNF1_ASPFN;  O94163, XYNF1_ASPOR;  B8NXJ2, XYNF3_ASPFN;
DR   Q96VB6, XYNF3_ASPOR;  P51584, XYNY_CLOTM ;  P10478, XYNZ_CLOTH ;
DR   O97402, XYN_PHACE  ;  P48793, XYN_TRIHA  ;
//
ID   3.2.1.9
DE   Deleted entry.
//
ID   3.2.1.10
DE   Oligo-1,6-glucosidase.
AN   Isomaltase.
AN   Oligosaccharide alpha-1,6-glucosidase.
AN   Sucrase-isomaltase.
CA   Hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides
CA   produced from starch and glycogen by alpha-amylase, and in isomaltose.
CC   -!- This enzyme, like EC 3.2.1.33, can release an alpha-1->6-linked
CC       glucose, whereas the shortest chain that can be released by
CC       EC 3.2.1.41, EC 3.2.1.142, and EC 3.2.1.68 is maltose.
CC   -!- It also hydrolyzes isomaltulose (palatinose), isomaltotriose and
CC       panose, but has no action on glycogen or phosphorylase limit dextrin.
CC   -!- The enzyme from intestinal mucosa is a single polypeptide chain that
CC       also catalyzes the reaction of EC 3.2.1.48.
CC   -!- Differs from EC 3.2.1.33 in its preference for short-chain substrates
CC       and in its not requiring the 6-glucosylated residue to be at a branch
CC       point, i.e. linked at both C-1 and C-4.
PR   PROSITE; PDOC00120;
DR   Q08295, IMA2_YEAST ;  P40884, IMA5_YEAST ;  P0CW40, MALX2_YEAST;
DR   P53051, MALX3_YEAST;  P0CW41, MALX4_YEAST;  O06994, O16G1_BACSU;
DR   O34364, O16G2_BACSU;  O05242, O16G3_BACSU;  P21332, O16G_BACCE ;
DR   Q45101, O16G_BACCO ;  P29093, O16G_BACF5 ;  Q9K8U9, O16G_BACHD ;
DR   P29094, O16G_BACTR ;  P14410, SUIS_HUMAN ;  P56729, SUIS_PIG   ;
DR   P07768, SUIS_RABIT ;  P23739, SUIS_RAT   ;  O62653, SUIS_SUNMU ;
//
ID   3.2.1.11
DE   Dextranase.
AN   Alpha-1,6-glucan-6-glucanohydrolase.
CA   Endohydrolysis of (1->6)-alpha-D-glucosidic linkages in dextran.
DR   P70744, DEXT_ARTGO ;  P39652, DEXT_ARTSD ;  P48845, DEXT_PENMI ;
DR   P39653, DEXT_STRDO ;  Q54443, DEXT_STRMU ;  Q59979, DEXT_STRSL ;
//
ID   3.2.1.12
DE   Transferred entry: 3.2.1.54.
//
ID   3.2.1.13
DE   Transferred entry: 3.2.1.54.
//
ID   3.2.1.14
DE   Chitinase.
AN   1,4-beta-poly-N-acetylglucosaminidase.
AN   Chitodextrinase.
AN   Poly-beta-glucosaminidase.
CA   Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages
CA   in chitin and chitodextrins.
CC   -!- Some chitinases also display the activity defined in EC 3.2.1.17.
PR   PROSITE; PDOC00620;
PR   PROSITE; PDOC00839;
DR   P11218, AGI_URTDI  ;  P84708, CAI_PHAVU  ;  Q5NB11, CHI10_ORYSJ;
DR   Q10S66, CHI11_ORYSJ;  P25765, CHI12_ORYSJ;  P32470, CHI1_APHAL ;
DR   P46876, CHI1_CANAL ;  P86078, CHI1_CAPAA ;  P86081, CHI1_CAPCH ;
DR   P29137, CHI1_CASSA ;  Q1E3R8, CHI1_COCIM ;  C5P230, CHI1_COCP7 ;
DR   P0CB51, CHI1_COCPS ;  P85343, CHI1_GINBI ;  Q39799, CHI1_GOSHI ;
DR   P11955, CHI1_HORVU ;  Q42993, CHI1_ORYSJ ;  P21225, CHI1_PEA   ;
DR   P29025, CHI1_RHINI ;  P29026, CHI1_RHIOL ;  P52403, CHI1_SOLTU ;
DR   P29115, CHI1_STROI ;  P85337, CHI1_TAXBA ;  Q41596, CHI1_THECC ;
DR   P08252, CHI1_TOBAC ;  Q06014, CHI2_ARAHY ;  Q09023, CHI2_BRANA ;
DR   P40953, CHI2_CANAL ;  P86079, CHI2_CAPAA ;  P86082, CHI2_CAPCH ;
DR   Q1EAR5, CHI2_COCIM ;  P54197, CHI2_COCP7 ;  Q39785, CHI2_GOSHI ;
DR   P23951, CHI2_HORVU ;  Q7DNA1, CHI2_ORYSJ ;  P21226, CHI2_PEA   ;
DR   P29027, CHI2_RHIOL ;  P52404, CHI2_SOLTU ;  P29116, CHI2_STROI ;
DR   P85338, CHI2_TAXBA ;  P24091, CHI2_TOBAC ;  Q06350, CHI2_YEAST ;
DR   Q06015, CHI3_ARAHY ;  P40954, CHI3_CANAL ;  P24626, CHI3_ORYSJ ;
DR   P52405, CHI3_SOLTU ;  P85355, CHI3_TAXBA ;  P29059, CHI3_TOBAC ;
DR   Q06016, CHI4_ARAHY ;  Q06209, CHI4_BRANA ;  O04138, CHI4_ORYSJ ;
DR   P27054, CHI4_PHAVU ;  P52406, CHI4_SOLTU ;  P48827, CHI4_TRIHA ;
DR   Q7Y1Z0, CHI5_ORYSJ ;  P36361, CHI5_PHAVU ;  Q6K8R2, CHI6_ORYSJ ;
DR   P16579, CHI6_POPTR ;  Q9SAY3, CHI7_ORYSI ;  Q7Y1Z1, CHI7_ORYSJ ;
DR   Q7XCK6, CHI8_ORYSJ ;  P16061, CHI8_POPTR ;  Q688M5, CHI9_ORYSJ ;
DR   P20533, CHIA1_BACCI;  Q06012, CHIA_ARAHY ;  P19172, CHIA_ARATH ;
DR   Q95M17, CHIA_BOVIN ;  P36908, CHIA_CICAR ;  P17541, CHIA_CUCSA ;
DR   P13656, CHIA_ECOLI ;  Q9BZP6, CHIA_HUMAN ;  P29022, CHIA_MAIZE ;
DR   Q91XA9, CHIA_MOUSE ;  P29024, CHIA_PHAAN ;  P32823, CHIA_PSEO7 ;
DR   Q6RY07, CHIA_RAT   ;  Q9FRV1, CHIA_SECCE ;  P07254, CHIA_SERMA ;
DR   Q40114, CHIA_SOLCI ;  Q05539, CHIA_SOLLC ;  P29060, CHIA_TOBAC ;
DR   Q06013, CHIB_ARAHY ;  P19171, CHIB_ARATH ;  P29023, CHIB_MAIZE ;
DR   P21227, CHIB_PEA   ;  P29031, CHIB_POPTR ;  P11797, CHIB_SERMA ;
DR   Q05540, CHIB_SOLLC ;  P29061, CHIB_TOBAC ;  P51613, CHIB_VITVI ;
DR   P29032, CHIC_POPTR ;  Q9FRV0, CHIC_SECCE ;  Q05538, CHIC_SOLLC ;
DR   P27050, CHID_BACCI ;  Q05537, CHID_SOLLC ;  P96156, CHID_VIBFU ;
DR   P36910, CHIE_BETVU ;  P42820, CHIP_BETVU ;  P17513, CHIP_TOBAC ;
DR   P17514, CHIQ_TOBAC ;  Q13231, CHIT1_HUMAN;  Q9D7Q1, CHIT1_MOUSE;
DR   Q9SLP4, CHIT1_TULBA;  Q9W092, CHIT2_DROME;  Q7M443, CHIT2_TULBA;
DR   Q9W5U2, CHIT3_DROME;  P51614, CHIT3_VITVI;  P86473, CHIT_ACTCH ;
DR   P86181, CHIT_AVESA ;  P29030, CHIT_BRUMA ;  Q11174, CHIT_CAEEL ;
DR   P85084, CHIT_CARPA ;  P80052, CHIT_DIOJA ;  P36362, CHIT_MANSE ;
DR   P41684, CHIT_NPVAC ;  O10363, CHIT_NPVOP ;  P29021, CHIT_PETHY ;
DR   P06215, CHIT_PHAVU ;  P14529, CHIT_SACEN ;  P05315, CHIT_SOLTU ;
DR   P36909, CHIT_STRLI ;  P11220, CHIT_STRPL ;  P84754, CHIT_STRVL ;
DR   P29029, CHIT_YEAST ;  P36907, CHIX_PEA   ;  Q05638, CHIX_STROI ;
DR   P81241, CHLY_CARPA ;  P23472, CHLY_HEVBR ;  P23473, CHLY_PARTH ;
DR   P15326, IAMY_COILA ;  P86799, IPLAA_MORAL;  P86800, IPLAB_MORAL;
DR   P09805, KTXA_KLULA ;
//
ID   3.2.1.15
DE   Polygalacturonase.
AN   Pectin depolymerase.
AN   Pectinase.
CA   Random hydrolysis of (1->4)-alpha-D-galactosiduronic linkages in pectate
CA   and other galacturonans.
PR   PROSITE; PDOC00415;
DR   O23147, ADPG1_ARATH;  Q8RY29, ADPG2_ARATH;  O74213, PGLR1_ASPAC;
DR   A1CIV8, PGLR1_ASPCL;  B8N8M2, PGLR1_ASPFN;  A2QAH3, PGLR1_ASPNC;
DR   P26213, PGLR1_ASPNG;  Q2UHL4, PGLR1_ASPOR;  Q0CMU3, PGLR1_ASPTN;
DR   Q00446, PGLR1_COLLN;  P18192, PGLR1_PECCC;  Q9Y834, PGLR1_PENOL;
DR   P58598, PGLR1_RALSO;  Q12708, PGLR1_SCLSC;  Q70HJ4, PGLR2_ASPAC;
DR   Q9P359, PGLR2_ASPAW;  Q8NK98, PGLR2_ASPKA;  A2R5S4, PGLR2_ASPNC;
DR   P26214, PGLR2_ASPNG;  P19805, PGLR2_ASPTU;  Q7M1E7, PGLR2_CHAOB;
DR   P43212, PGLR2_CRYJA;  Q9FY19, PGLR2_JUNAS;  P26509, PGLR2_PECCC;
DR   Q9Y833, PGLR2_PENOL;  P20041, PGLR2_RALSO;  Q9LW07, PGLR3_ARATH;
DR   Q949Z1, PGLR4_ARATH;  Q94AJ5, PGLR5_ARATH;  O22818, PGLR6_ARATH;
DR   Q9P358, PGLRA_ASPAW;  B0Y4Z4, PGLRA_ASPFC;  P41749, PGLRA_ASPFL;
DR   Q4WQT2, PGLRA_ASPFU;  Q8NK99, PGLRA_ASPKA;  A2R8F8, PGLRA_ASPNC;
DR   Q9P4W4, PGLRA_ASPNG;  P49575, PGLRA_ASPPA;  A1CVV8, PGLRA_NEOFI;
DR   B0YAH0, PGLRB_ASPFC;  P41750, PGLRB_ASPFL;  B8N7Z8, PGLRB_ASPFN;
DR   Q4WBE1, PGLRB_ASPFU;  Q1HAY5, PGLRB_ASPKA;  A2QCV8, PGLRB_ASPNC;
DR   Q9P4W3, PGLRB_ASPNG;  P35335, PGLRB_ASPOR;  Q5B508, PGLRB_EMENI;
DR   A1DAQ2, PGLRB_NEOFI;  Q70HJ3, PGLRC_ASPAC;  A2QL39, PGLRC_ASPNC;
DR   Q12554, PGLRC_ASPNG;  B8MW78, PGLRD_ASPFN;  A2QTU0, PGLRD_ASPNC;
DR   Q9P4W2, PGLRD_ASPNG;  Q2UT29, PGLRD_ASPOR;  Q5AYH4, PGLRD_EMENI;
DR   A1DBR6, PGLRD_NEOFI;  A2QBB6, PGLRE_ASPNC;  O42809, PGLRE_ASPNG;
DR   P35336, PGLR_ACTDE ;  B0XPA1, PGLR_ASPFC ;  Q4WR80, PGLR_ASPFU ;
DR   P35337, PGLR_BRANA ;  P26215, PGLR_COCCA ;  P81179, PGLR_DIAAB ;
DR   Q5ATQ3, PGLR_EMENI ;  Q07181, PGLR_GIBFU ;  Q39766, PGLR_GOSBA ;
DR   Q39786, PGLR_GOSHI ;  P48978, PGLR_MALDO ;  Q40312, PGLR_MEDSA ;
DR   A1D145, PGLR_NEOFI ;  Q9Y718, PGLR_PENDI ;  O59925, PGLR_PENEN ;
DR   O93883, PGLR_PENGR ;  O42824, PGLR_PENJA ;  Q02096, PGLR_PERAE ;
DR   O97400, PGLR_PHACE ;  P48979, PGLR_PRUPE ;  P27644, PGLR_RHIRD ;
DR   P05117, PGLR_SOLLC ;  Q05967, PGLR_TOBAC ;  A7PZL3, PGLR_VITVI ;
DR   P47180, PGLR_YEAST ;  Q9SFB7, QRT2_ARATH ;  O49432, QRT3_ARATH ;
//
ID   3.2.1.16
DE   Deleted entry.
//
ID   3.2.1.17
DE   Lysozyme.
AN   Muramidase.
CA   Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and
CA   N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-
CA   D-glucosamine residues in chitodextrins.
CC   -!- Cf. EC 3.2.1.14.
PR   PROSITE; PDOC00119;
PR   PROSITE; PDOC00737;
DR   Q9CIT4, ACMA_LACLA ;  P0C2T5, ACMA_LACLC ;  A2RHZ5, ACMA_LACLM ;
DR   Q556R7, CF50_DICDI ;  P13656, CHIA_ECOLI ;  P81241, CHLY_CARPA ;
DR   P23472, CHLY_HEVBR ;  P23473, CHLY_PARTH ;  P10773, LYB_BACSU  ;
DR   P00718, LYG_ANSAN  ;  Q7LZR3, LYG_CASCA  ;  P27042, LYG_CHICK  ;
DR   P00717, LYG_CYGAT  ;  Q8JFR1, LYG_CYPCA  ;  Q90X99, LYG_EPICO  ;
DR   Q90VZ3, LYG_PAROL  ;  P00719, LYG_STRCA  ;  P61133, LYG_TAKRU  ;
DR   P83673, LYS1_CRAVI ;  P85152, LYS1_LYSSX ;  Q7YT16, LYS1_MUSDO ;
DR   Q1XG90, LYS2_CRAVI ;  B3A003, LYS3_CRAVI ;  Q27650, LYS4_ENTHI ;
DR   P83971, LYSA_DROME ;  Q8T1G6, LYSB_DICDI ;  Q08694, LYSB_DROME ;
DR   P00705, LYSC1_ANAPL;  Q17005, LYSC1_ANOGA;  Q06285, LYSC1_BOVIN;
DR   P81708, LYSC1_CANFA;  P37713, LYSC1_CAPHI;  P11376, LYSC1_HORSE;
DR   P12067, LYSC1_PIG  ;  P00697, LYSC1_RAT  ;  P17607, LYSC1_SHEEP;
DR   P37156, LYSC1_TACAC;  Q06283, LYSC2_BOVIN;  P81709, LYSC2_CANFA;
DR   P37714, LYSC2_CAPHI;  P81710, LYSC2_HORSE;  P11941, LYSC2_ONCMY;
DR   P12068, LYSC2_PIG  ;  Q05820, LYSC2_RAT  ;  P00706, LYSC3_ANAPL;
DR   Q06284, LYSC3_BOVIN;  P12069, LYSC3_PIG  ;  Q9TUN1, LYSC3_SHEEP;
DR   P80190, LYSCK_SHEEP;  P80189, LYSCN_BOVIN;  Q27996, LYSCT_BOVIN;
DR   Q7LZQ2, LYSC_AIXSP ;  P79687, LYSC_ALLNI ;  P85345, LYSC_AMYCA ;
DR   P12066, LYSC_AXIAX ;  P04421, LYSC_BOVIN ;  P00699, LYSC_CALCC ;
DR   P79158, LYSC_CALJA ;  P37712, LYSC_CAMDR ;  Q7LZQ0, LYSC_CATWA ;
DR   P61630, LYSC_CERTO ;  P84492, LYSC_CHEMY ;  P00698, LYSC_CHICK ;
DR   P61633, LYSC_CHLAE ;  P22910, LYSC_CHRAM ;  P61631, LYSC_COLAN ;
DR   P61632, LYSC_COLGU ;  P00708, LYSC_COLLI ;  P00700, LYSC_COLVI ;
DR   P00701, LYSC_COTJA ;  Q7LZQ3, LYSC_CRAFA ;  Q8T1G5, LYSC_DICDI ;
DR   P11375, LYSC_EQUAS ;  P61634, LYSC_ERYPA ;  P37155, LYSC_FELCA ;
DR   P79179, LYSC_GORGO ;  Q659U5, LYSC_HALGR ;  P61626, LYSC_HUMAN ;
DR   P79180, LYSC_HYLLA ;  Q659U0, LYSC_LEPWE ;  Q7LZP9, LYSC_LOPIM ;
DR   P24364, LYSC_LOPLE ;  P30201, LYSC_MACMU ;  P00703, LYSC_MELGA ;
DR   P79806, LYSC_MIOTA ;  P79811, LYSC_NASLA ;  P00704, LYSC_NUMME ;
DR   Q91159, LYSC_OPIHO ;  P00707, LYSC_ORTVE ;  P61627, LYSC_PANPA ;
DR   P61628, LYSC_PANTR ;  P61629, LYSC_PAPAN ;  Q9DD65, LYSC_PAROL ;
DR   P19849, LYSC_PAVCR ;  Q7LZQ1, LYSC_PELSI ;  P00702, LYSC_PHACO ;
DR   P49663, LYSC_PHAVE ;  Q659U1, LYSC_PHOVI ;  P79239, LYSC_PONPY ;
DR   Q9PU28, LYSC_PSEMX ;  P21776, LYSC_PSEPE ;  P79847, LYSC_PYGNE ;
DR   P16973, LYSC_RABIT ;  P79268, LYSC_SAGOE ;  P79294, LYSC_SAISC ;
DR   P67977, LYSC_SEMEN ;  P24533, LYSC_SYRRE ;  P81711, LYSC_SYRSO ;
DR   P61944, LYSC_TAKRU ;  P0C8X2, LYSC_TITST ;  P67980, LYSC_TRAFR ;
DR   P67979, LYSC_TRAOB ;  Q7LZI3, LYSC_TRASA ;  Q7LZT2, LYSC_TRATE ;
DR   P67978, LYSC_TRAVT ;  P51782, LYSC_TRIVU ;  Q556Y7, LYSD_DICDI ;
DR   P83972, LYSD_DROME ;  P78285, LYSD_ECOLI ;  P37159, LYSE_DROME ;
DR   Q86KC1, LYSG2_DICDI;  Q8T2I5, LYSG3_DICDI;  Q54BQ8, LYSG4_DICDI;
DR   Q54BL8, LYSG5_DICDI;  Q6B410, LYSI_BOVIN ;  P25310, LYSM1_STRGL;
DR   Q6B411, LYSM_BOVIN ;  P29615, LYSP_DROME ;  P76159, LYSQ_ECOLI ;
DR   P37160, LYSS_DROME ;  Q556F2, LYST1_DICDI;  Q86AA1, LYST2_DICDI;
DR   P37161, LYSX_DROME ;  Q7SID7, LYS_ANTMY  ;  P37715, LYS_ASTRU  ;
DR   P48816, LYS_BOMMO  ;  P68920, LYS_BP933  ;  Q9T1T5, LYS_BPAPS  ;
DR   Q37896, LYS_BPB03  ;  P15057, LYS_BPCP1  ;  P19385, LYS_BPCP7  ;
DR   P19386, LYS_BPCP9  ;  Q9ZXB7, LYS_BPH19  ;  P51728, LYS_BPHP1  ;
DR   P62692, LYS_BPLC2  ;  Q9T1X2, LYS_BPMU   ;  P33486, LYS_BPMV1  ;
DR   O64362, LYS_BPN15  ;  Q37875, LYS_BPP1   ;  P51771, LYS_BPP2   ;
DR   P27359, LYS_BPP21  ;  P09963, LYS_BPP22  ;  P10439, LYS_BPPA2  ;
DR   P11187, LYS_BPPH2  ;  P62693, LYS_BPPHV  ;  O80292, LYS_BPPS1  ;
DR   O80288, LYS_BPPS3  ;  P07540, LYS_BPPZA  ;  P00720, LYS_BPT4   ;
DR   P68921, LYS_BPVT2  ;  P85045, LYS_BUFAN  ;  P34020, LYS_CLOAB  ;
DR   P26836, LYS_CLOPE  ;  Q6L6Q6, LYS_CRAGI  ;  P82175, LYS_ESTAC  ;
DR   P82174, LYS_GALME  ;  P05105, LYS_HYACE  ;  P50717, LYS_HYPCU  ;
DR   P03706, LYS_LAMBD  ;  P86383, LYS_MERLU  ;  Q6L6Q5, LYS_OSTED  ;
DR   P50718, LYS_TRINI  ;  P17897, LYZ1_MOUSE ;  P08905, LYZ2_MOUSE ;
DR   A0JNM6, LYZL1_BOVIN;  Q6UWQ5, LYZL1_HUMAN;  Q9CPX3, LYZL1_MOUSE;
DR   Q7Z4W2, LYZL2_HUMAN;  Q32PD6, LYZL5_BOVIN;  Q96QH8, LYZL5_HUMAN;
DR   A2AE20, LYZL5_MOUSE;  Q29RT1, LYZL6_BOVIN;  O75951, LYZL6_HUMAN;
DR   Q9DA11, LYZL6_MOUSE;  P21270, LY_BPSF6   ;  P39046, MUR2_ENTHR ;
DR   P16009, VG05_BPT4  ;  P09425, VG25_BPT4  ;  P13559, VLYS_BPPRD ;
//
ID   3.2.1.18
DE   Exo-alpha-sialidase.
AN   Alpha-neuraminidase.
AN   N-acylneuraminate glycohydrolase.
AN   Neuraminidase.
AN   Sialidase.
CA   Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic
CA   linkages of terminal sialic acid residues in oligosaccharides,
CA   glycoproteins, glycolipids, colominic acid and synthetic substrates.
CC   -!- The enzyme does not act on 4-O-acetylated sialic acids.
CC   -!- An endo-alpha-sialidase activity is listed as EC 3.2.1.129.
CC   -!- See also EC 4.2.2.15.
DR   P18269, 8511_TRYCR ;  P18270, 8512_TRYCR ;  P18271, 8513_TRYCR ;
DR   P19762, HN_MUMP1   ;  P11235, HN_MUMPM   ;  P10866, HN_MUMPR   ;
DR   P12554, HN_NDVA    ;  P32884, HN_NDVB    ;  Q91UL0, HN_NDVB1   ;
DR   P35740, HN_NDVC    ;  P12555, HN_NDVD    ;  P35741, HN_NDVH3   ;
DR   P12559, HN_NDVH4   ;  P12556, HN_NDVI    ;  P35742, HN_NDVJ    ;
DR   Q9Q2W5, HN_NDVK    ;  P35743, HN_NDVL    ;  P12557, HN_NDVM    ;
DR   P13850, HN_NDVQ    ;  P12553, HN_NDVTG   ;  P12558, HN_NDVU    ;
DR   P16071, HN_PI1HW   ;  P25465, HN_PI2H    ;  P25466, HN_PI2HT   ;
DR   P06167, HN_PI3B    ;  P08492, HN_PI3H4   ;  P12561, HN_PI3HA   ;
DR   P12562, HN_PI3HT   ;  P12563, HN_PI3HU   ;  P12564, HN_PI3HV   ;
DR   P12565, HN_PI3HW   ;  P12566, HN_PI3HX   ;  P21526, HN_PI4HA   ;
DR   Q783Y1, HN_SENDA   ;  P19758, HN_SENDF   ;  P03425, HN_SENDH   ;
DR   Q88261, HN_SENDO   ;  P04853, HN_SENDZ   ;  P25180, HN_SV41    ;
DR   P04850, HN_SV5     ;  P28883, HN_SV5CM   ;  P28884, HN_SV5CP   ;
DR   P28885, HN_SV5LN   ;  P62575, NANA_STRPN ;  P62576, NANA_STRR6 ;
DR   Q54727, NANB_STRPN ;  P31206, NANH_BACFR ;  P10481, NANH_CLOPE ;
DR   P29767, NANH_CLOSE ;  P15698, NANH_CLOSO ;  Q02834, NANH_MICVI ;
DR   P29768, NANH_SALTY ;  A5F7A4, NANH_VIBC3 ;  P0C6E9, NANH_VIBCH ;
DR   A6BMK7, NEUR1_BOVIN;  Q99519, NEUR1_HUMAN;  O35657, NEUR1_MOUSE;
DR   A5PF10, NEUR1_PIG  ;  Q5RAF4, NEUR1_PONAB;  Q99PW3, NEUR1_RAT  ;
DR   Q64393, NEUR2_CRIGR;  Q9Y3R4, NEUR2_HUMAN;  Q9JMH3, NEUR2_MOUSE;
DR   Q64627, NEUR2_RAT  ;  O97859, NEUR3_BOVIN;  Q9UQ49, NEUR3_HUMAN;
DR   Q9JMH7, NEUR3_MOUSE;  Q99PW5, NEUR3_RAT  ;  Q8WWR8, NEUR4_HUMAN;
DR   Q8BZL1, NEUR4_MOUSE;  P18881, NRAM_I000F ;  Q8QPK2, NRAM_I00A0 ;
DR   Q289M4, NRAM_I00A1 ;  Q809V0, NRAM_I01A0 ;  Q809V4, NRAM_I01A1 ;
DR   Q809V2, NRAM_I01A2 ;  Q809U7, NRAM_I01A3 ;  Q6DPK2, NRAM_I02A1 ;
DR   Q6DPK1, NRAM_I02A2 ;  Q6DPK0, NRAM_I02A3 ;  Q6DPJ9, NRAM_I02A4 ;
DR   Q6J8D5, NRAM_I02A5 ;  Q6DPJ8, NRAM_I02A6 ;  Q6DPI6, NRAM_I02A7 ;
DR   Q6J8E4, NRAM_I03A0 ;  Q6DPH9, NRAM_I03A1 ;  Q2LFV4, NRAM_I05A1 ;
DR   B4URD9, NRAM_I06A0 ;  A8C8J7, NRAM_I07A0 ;  Q9IGQ6, NRAM_I18A0 ;
DR   P03470, NRAM_I33A0 ;  Q64968, NRAM_I34A0 ;  P03468, NRAM_I34A1 ;
DR   A4GCM2, NRAM_I35A3 ;  A4GCI9, NRAM_I36A0 ;  Q0HD57, NRAM_I40A0 ;
DR   A4GCL1, NRAM_I43A0 ;  A4U6V5, NRAM_I45A0 ;  Q8JSD9, NRAM_I47A0 ;
DR   P03480, NRAM_I49A1 ;  A4U7A9, NRAM_I51A0 ;  P31349, NRAM_I54A0 ;
DR   A4K146, NRAM_I54A2 ;  A3KF10, NRAM_I56A1 ;  Q6XV27, NRAM_I56A2 ;
DR   P88838, NRAM_I56A3 ;  Q1K9Q1, NRAM_I57A0 ;  Q67212, NRAM_I57A1 ;
DR   Q67214, NRAM_I57A2 ;  P03484, NRAM_I57A4 ;  Q6XUE4, NRAM_I57A5 ;
DR   Q710U6, NRAM_I59A0 ;  Q6XUD6, NRAM_I60A0 ;  Q6XV52, NRAM_I61A0 ;
DR   B3EUQ9, NRAM_I61A1 ;  Q595Z2, NRAM_I63A1 ;  Q07579, NRAM_I63A2 ;
DR   Q07599, NRAM_I63A3 ;  Q07584, NRAM_I65A0 ;  Q0A456, NRAM_I66A1 ;
DR   P06820, NRAM_I67A0 ;  A8C8W6, NRAM_I67A2 ;  Q75VQ4, NRAM_I68A0 ;
DR   P03477, NRAM_I68A3 ;  Q91MA2, NRAM_I68A4 ;  Q6XUA7, NRAM_I68A5 ;
DR   P03473, NRAM_I68A6 ;  Q6XTN2, NRAM_I69A0 ;  Q07581, NRAM_I69A2 ;
DR   Q6XTM7, NRAM_I70A0 ;  P03471, NRAM_I71A1 ;  P03476, NRAM_I71A2 ;
DR   Q07576, NRAM_I72A0 ;  Q07571, NRAM_I72A1 ;  P03483, NRAM_I72A2 ;
DR   P03475, NRAM_I72A3 ;  Q2ICQ7, NRAM_I72A4 ;  P03478, NRAM_I72A5 ;
DR   P06819, NRAM_I73A0 ;  Q1PUD6, NRAM_I73A5 ;  P08327, NRAM_I74A1 ;
DR   Q07573, NRAM_I74A2 ;  Q30NP8, NRAM_I75A0 ;  P03482, NRAM_I75A3 ;
DR   P03472, NRAM_I75A5 ;  P03479, NRAM_I76A1 ;  Q2RFA3, NRAM_I76A6 ;
DR   Q76WJ1, NRAM_I76A7 ;  Q09104, NRAM_I76A9 ;  Q09105, NRAM_I76AB ;
DR   Q9IGQ0, NRAM_I76AI ;  Q6XV26, NRAM_I76AK ;  Q9EA42, NRAM_I77A4 ;
DR   A4GBY0, NRAM_I77AA ;  P03469, NRAM_I77AB ;  Q6XV23, NRAM_I77AF ;
DR   Q6XV28, NRAM_I77AG ;  Q75VQ0, NRAM_I77AH ;  P03481, NRAM_I78A0 ;
DR   Q2VNF0, NRAM_I78A7 ;  Q2VND0, NRAM_I78A8 ;  Q09106, NRAM_I78AB ;
DR   Q07585, NRAM_I78AC ;  P06818, NRAM_I79A0 ;  P31348, NRAM_I79A4 ;
DR   Q07580, NRAM_I79A6 ;  Q6XV43, NRAM_I79A7 ;  Q2VC95, NRAM_I80A2 ;
DR   Q2RCH3, NRAM_I80A4 ;  Q07572, NRAM_I80A6 ;  Q20NP0, NRAM_I80A8 ;
DR   A4GCK0, NRAM_I80AA ;  Q20NV8, NRAM_I80AD ;  P08326, NRAM_I81A2 ;
DR   P26143, NRAM_I82A2 ;  Q67344, NRAM_I82A7 ;  P11485, NRAM_I83A1 ;
DR   Q0A2G2, NRAM_I83A4 ;  Q0A2I4, NRAM_I83A5 ;  P09573, NRAM_I83A6 ;
DR   P09574, NRAM_I83A7 ;  Q38SQ5, NRAM_I83A8 ;  Q07574, NRAM_I84A0 ;
DR   P05803, NRAM_I84A1 ;  Q6XV24, NRAM_I84A4 ;  Q0A2R1, NRAM_I85A3 ;
DR   Q6TXB9, NRAM_I85A5 ;  P31510, NRAM_I85A8 ;  Q07582, NRAM_I86A3 ;
DR   Q07570, NRAM_I88A1 ;  Q07577, NRAM_I88A4 ;  Q07578, NRAM_I89A7 ;
DR   Q07583, NRAM_I90A1 ;  Q07575, NRAM_I91A0 ;  O91744, NRAM_I93A0 ;
DR   Q9Q0U7, NRAM_I96A0 ;  O91745, NRAM_I96A1 ;  A3DRP3, NRAM_I96A2 ;
DR   Q07FI2, NRAM_I96A3 ;  Q9WAA1, NRAM_I97A0 ;  Q9W7Y7, NRAM_I97A1 ;
DR   P27907, NRAM_INBBE ;  P16191, NRAM_INBHK ;  P03474, NRAM_INBLE ;
DR   P67923, NRAM_INBLN ;  P16195, NRAM_INBMD ;  P67907, NRAM_INBME ;
DR   P16199, NRAM_INBMF ;  P16201, NRAM_INBOR ;  P16203, NRAM_INBSI ;
DR   P16205, NRAM_INBUS ;  P16207, NRAM_INBVI ;  Q90021, NRAM_INBYB ;
DR   P23253, TCNA_TRYCR ;
//
ID   3.2.1.19
DE   Deleted entry.
//
ID   3.2.1.20
DE   Alpha-glucosidase.
AN   Acid maltase.
AN   Glucoinvertase.
AN   Glucosidosucrase.
AN   Lysosomal alpha-glucosidase.
AN   Maltase.
AN   Maltase-glucoamylase.
CA   Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose
CA   residues with release of alpha-D-glucose.
CC   -!- Group of enzymes whose specificity is directed mainly toward the
CC       exohydrolysis of 1,4-alpha-glucosidic linkages, and that hydrolyze
CC       oligosaccharides rapidly, relative to polysaccharides, which are
CC       hydrolyzed relatively slowly, or not at all.
CC   -!- The intestinal enzyme also hydrolyzes polysaccharides, catalyzing the
CC       reactions of EC 3.2.1.3, and, more slowly, hydrolyzes 1,6-alpha-D-
CC       glucose links.
PR   PROSITE; PDOC00120;
PR   PROSITE; PDOC01027;
DR   A1CNK4, AGDC_ASPCL ;  B0XNL6, AGDC_ASPFC ;  B8MZ41, AGDC_ASPFN ;
DR   Q4WRH9, AGDC_ASPFU ;  Q2UQV7, AGDC_ASPOR ;  Q0CMA7, AGDC_ASPTN ;
DR   Q5AWI5, AGDC_EMENI ;  A1D1E6, AGDC_NEOFI ;  Q9F234, AGL2_BACTQ ;
DR   Q9Z3R8, AGLA_RHIME ;  O33830, AGLA_THEMA ;  P56526, AGLU_ASPNG ;
DR   Q12558, AGLU_ASPOR ;  O04931, AGLU_BETVU ;  P29064, AGLU_CANTS ;
DR   Q43763, AGLU_HORVU ;  Q92442, AGLU_MUCJA ;  Q653V7, AGLU_ORYSJ ;
DR   Q9C0Y4, AGLU_SCHPO ;  O04893, AGLU_SPIOL ;  D0KQM8, AGLU_SULS9 ;
DR   P0CD66, AGLU_SULSO ;  O00906, AGLU_TETPY ;  P43473, AGL_PEDPE  ;
DR   Q8TET4, GANC_HUMAN ;  Q9MYM4, LYAG_BOVIN ;  P10253, LYAG_HUMAN ;
DR   P70699, LYAG_MOUSE ;  Q5R7A9, LYAG_PONAB ;  Q6P7A9, LYAG_RAT   ;
DR   P53341, MAL12_YEAST;  Q17058, MAL1_APIME ;  P07191, MAL1_DROME ;
DR   O16098, MAL1_DROVI ;  P07190, MAL2_DROME ;  O16099, MAL2_DROVI ;
DR   P38158, MAL32_YEAST;  P07192, MAL3_DROME ;  P07265, MAL62_YEASX;
DR   P13080, MALT_AEDAE ;  P80072, MALT_BACTQ ;  Q02751, MALT_CANAL ;
DR   Q9P6J3, MALT_SCHPO ;  P21517, MALZ_ECOLI ;  O43451, MGA_HUMAN  ;
DR   Q9AI65, PALH_ERWRD ;  P32138, YIHQ_ECOLI ;
//
ID   3.2.1.21
DE   Beta-glucosidase.
AN   Amygdalase.
AN   Beta-D-glucoside glucohydrolase.
AN   Cellobiase.
AN   Gentobiase.
CA   Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with
CA   release of beta-D-glucose.
CC   -!- Wide specificity for beta-D-glucosides.
CC   -!- Some examples also hydrolyze one or more of the following: beta-D-
CC       galactosides, alpha-L-arabinosides, beta-D-xylosides and beta-D-
CC       fucosides.
PR   PROSITE; PDOC00495;
PR   PROSITE; PDOC00621;
DR   A1CNK4, AGDC_ASPCL ;  B0XNL6, AGDC_ASPFC ;  B8MZ41, AGDC_ASPFN ;
DR   Q4WRH9, AGDC_ASPFU ;  Q2UQV7, AGDC_ASPOR ;  Q0CMA7, AGDC_ASPTN ;
DR   Q5AWI5, AGDC_EMENI ;  A1D1E6, AGDC_NEOFI ;  Q3ECW8, BGL01_ARATH;
DR   Q5QMT0, BGL01_ORYSJ;  Q9FMD8, BGL02_ARATH;  B7F8N7, BGL02_ORYSJ;
DR   O65458, BGL03_ARATH;  Q8RZL1, BGL03_ORYSJ;  Q9ZUI3, BGL04_ARATH;
DR   Q5N863, BGL04_ORYSJ;  Q8RXN9, BGL05_ARATH;  Q5JK35, BGL05_ORYSJ;
DR   Q682B4, BGL06_ARATH;  Q8L7J2, BGL06_ORYSJ;  Q9LZJ1, BGL07_ARATH;
DR   Q75I93, BGL07_ORYSJ;  Q67XN2, BGL08_ARATH;  Q75I94, BGL08_ORYSJ;
DR   Q9STP4, BGL09_ARATH;  B7ECS8, BGL09_ORYSJ;  Q93ZI4, BGL10_ARATH;
DR   Q7F9K4, BGL10_ORYSJ;  B3H5Q1, BGL11_ARATH;  Q7XKV5, BGL11_ORYSJ;
DR   Q9FH03, BGL12_ARATH;  Q7XKV4, BGL12_ORYSJ;  Q9LU02, BGL13_ARATH;
DR   Q7XKV2, BGL13_ORYSJ;  Q9SLA0, BGL14_ARATH;  O64879, BGL15_ARATH;
DR   Q7XPY5, BGL15_ORYSJ;  Q9M1D0, BGL16_ARATH;  Q7XSK2, BGL16_ORYSJ;
DR   O64882, BGL17_ARATH;  Q7XSK1, BGL17_ORYSJ;  Q9SE50, BGL18_ARATH;
DR   Q7XSK0, BGL18_ORYSJ;  Q9LIF9, BGL19_ARATH;  Q0DIT2, BGL19_ORYSJ;
DR   Q25BW5, BGL1A_PHACH;  Q25BW4, BGL1B_PHACH;  P48825, BGL1_ASPAC ;
DR   P85516, BGL1_CLAFU ;  P22506, BGL1_SACFI ;  Q84WV2, BGL20_ARATH;
DR   B9FHH2, BGL20_ORYSJ;  Q9C525, BGL21_ARATH;  Q60DY1, BGL21_ORYSJ;
DR   Q9C8Y9, BGL22_ARATH;  Q60DX8, BGL22_ORYSJ;  Q9SR37, BGL23_ARATH;
DR   Q6L597, BGL23_ORYSJ;  Q9LKR7, BGL24_ARATH;  Q5Z9Z0, BGL24_ORYSJ;
DR   Q0DA21, BGL25_ORYSJ;  O64883, BGL26_ARATH;  A3BMZ5, BGL26_ORYSJ;
DR   Q9M1D1, BGL27_ARATH;  Q84YK7, BGL27_ORYSJ;  Q4V3B3, BGL28_ARATH;
DR   Q7EXZ4, BGL28_ORYSJ;  Q8GXT2, BGL29_ARATH;  A3C053, BGL29_ORYSJ;
DR   P85517, BGL2_CLAFU ;  P22507, BGL2_SACFI ;  Q9M1C9, BGL30_ARATH;
DR   Q0J0N4, BGL30_ORYSJ;  Q9FLU9, BGL31_ARATH;  B7F7K7, BGL31_ORYSJ;
DR   Q9FLU8, BGL32_ARATH;  Q0J0G2, BGL32_ORYSJ;  O48779, BGL33_ARATH;
DR   Q8GRX1, BGL34_ARATH;  Q339X2, BGL34_ORYSJ;  Q3ECS3, BGL35_ARATH;
DR   Q53NF0, BGL35_ORYSJ;  P37702, BGL38_ARATH;  Q2QSR8, BGL38_ORYSJ;
DR   P29090, BGL3_ASPWE ;  Q9FZE0, BGL40_ARATH;  Q9FIU7, BGL41_ARATH;
DR   Q9FIW4, BGL42_ARATH;  Q9LV34, BGL43_ARATH;  Q9LV33, BGL44_ARATH;
DR   O80689, BGL45_ARATH;  O80690, BGL46_ARATH;  Q9SVS1, BGL47_ARATH;
DR   A1CR85, BGLA_ASPCL ;  B0XPE1, BGLA_ASPFC ;  B8NRX2, BGLA_ASPFN ;
DR   Q4WJJ3, BGLA_ASPFU ;  P87076, BGLA_ASPKA ;  A2RAL4, BGLA_ASPNC ;
DR   Q2UUD6, BGLA_ASPOR ;  D0VKF5, BGLA_ASPTE ;  Q0CTD7, BGLA_ASPTN ;
DR   Q03506, BGLA_BACCI ;  P26208, BGLA_CLOTH ;  Q5B5S8, BGLA_EMENI ;
DR   Q59437, BGLA_ENTAG ;  A1D451, BGLA_NEOFI ;  P22073, BGLA_PAEPO ;
DR   Q08638, BGLA_THEMA ;  P0C946, BGLA_THENE ;  B9K7M5, BGLA_THENN ;
DR   P14002, BGLB_CLOTH ;  Q5BFG8, BGLB_EMENI ;  P22505, BGLB_PAEPO ;
DR   P38645, BGLB_THEBI ;  B8NGU6, BGLC_ASPFN ;  Q2UFP8, BGLC_ASPOR ;
DR   Q5BCC6, BGLC_EMENI ;  P49235, BGLC_MAIZE ;  B8NJF4, BGLD_ASPFN ;
DR   A2QPK4, BGLD_ASPNC ;  Q2UNR0, BGLD_ASPOR ;  Q5AUW5, BGLD_EMENI ;
DR   A1CMH6, BGLE_ASPCL ;  B0YD91, BGLE_ASPFC ;  Q4WD56, BGLE_ASPFU ;
DR   Q2UTX5, BGLE_ASPOR ;  Q5AYH8, BGLE_EMENI ;  A1DLJ5, BGLE_NEOFI ;
DR   P94248, BGLFU_BIFBR;  B0Y7Q8, BGLF_ASPFC ;  B8NP65, BGLF_ASPFN ;
DR   Q4WMU3, BGLF_ASPFU ;  Q2UN12, BGLF_ASPOR ;  Q0CI67, BGLF_ASPTN ;
DR   Q5B6C6, BGLF_EMENI ;  A1DMR8, BGLF_NEOFI ;  B8NMR5, BGLG_ASPFN ;
DR   Q2U325, BGLG_ASPOR ;  Q0CUC1, BGLG_ASPTN ;  Q5B0F4, BGLG_EMENI ;
DR   A1DC16, BGLG_NEOFI ;  A1CUR8, BGLH_ASPCL ;  B0XM94, BGLH_ASPFC ;
DR   B8NPL7, BGLH_ASPFN ;  Q4WL79, BGLH_ASPFU ;  Q2U9M7, BGLH_ASPOR ;
DR   Q5B6C7, BGLH_EMENI ;  A1DPG0, BGLH_NEOFI ;  A1CA51, BGLI_ASPCL ;
DR   B0Y3M6, BGLI_ASPFC ;  B8NDE2, BGLI_ASPFN ;  Q4WU49, BGLI_ASPFU ;
DR   A2R989, BGLI_ASPNC ;  Q2U8Y5, BGLI_ASPOR ;  Q0CAF5, BGLI_ASPTN ;
DR   Q5BB53, BGLI_EMENI ;  A1DFA8, BGLI_NEOFI ;  B0Y8M8, BGLJ_ASPFC ;
DR   Q4WLY1, BGLJ_ASPFU ;  Q5AV15, BGLJ_EMENI ;  A1DNN8, BGLJ_NEOFI ;
DR   B0YBJ3, BGLK_ASPFC ;  Q4WA69, BGLK_ASPFU ;  Q5BA18, BGLK_EMENI ;
DR   B0YB65, BGLL_ASPFC ;  Q4WGT3, BGLL_ASPFU ;  Q0CEF3, BGLL_ASPTN ;
DR   Q5B9F2, BGLL_EMENI ;  A1DCV5, BGLL_NEOFI ;  B0XPB8, BGLM_ASPFC ;
DR   B8N5S6, BGLM_ASPFN ;  Q4WR62, BGLM_ASPFU ;  A5ABF5, BGLM_ASPNC ;
DR   Q2UDK7, BGLM_ASPOR ;  Q0C7L4, BGLM_ASPTN ;  Q5AWD4, BGLM_EMENI ;
DR   A1D122, BGLM_NEOFI ;  Q5B681, BGLN_EMENI ;  Q5BG51, BGLO_EMENI ;
DR   P12614, BGLS_AGRSA ;  P16084, BGLS_BUTFI ;  P10482, BGLS_CALSA ;
DR   P06835, BGLS_HANAN ;  P07337, BGLS_KLUMA ;  P27034, BGLS_RHIRD ;
DR   P15885, BGLS_RUMAL ;  P29091, BGLS_SCHCO ;  Q9P6J6, BGLS_SCHPO ;
DR   P26204, BGLS_TRIRP ;  P26205, BGLT_TRIRP ;  P33363, BGLX_ECOLI ;
DR   Q46684, BGLX_ERWCH ;  Q56078, BGLX_SALTY ;  A1C499, BTGE_ASPCL ;
DR   B0Y9Q9, BTGE_ASPFC ;  B8MXP5, BTGE_ASPFN ;  Q4WC60, BTGE_ASPFU ;
DR   Q2US39, BTGE_ASPOR ;  Q0CEX9, BTGE_ASPTN ;  Q5BD29, BTGE_EMENI ;
DR   A1DBG6, BTGE_NEOFI ;  P97265, GBA3_CAVPO ;  Q9H227, GBA3_HUMAN ;
DR   Q5RF65, GBA3_PONAB ;  Q23892, GLUA_DICDI ;  Q7WUL3, NAG3_CELFI ;
//
ID   3.2.1.22
DE   Alpha-galactosidase.
AN   Melibiase.
CA   Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-
CA   D-galactosides, including galactose oligosaccharides, galactomannans and
CA   galactolipids.
CF   Magnesium; NAD.
CC   -!- Also hydrolyzes alpha-D-fucosides.
PR   PROSITE; PDOC00443;
PR   PROSITE; PDOC01027;
DR   P43467, AGAL1_PEDPE;  P43469, AGAL2_PEDPE;  Q92457, AGAL2_TRIRE;
DR   Q92451, AGAL3_TRIRE;  C8VJZ7, AGAL8_EMENI;  A1CBW8, AGALA_ASPCL;
DR   B8MWJ5, AGALA_ASPFN;  Q4WVZ3, AGALA_ASPFU;  A2QL72, AGALA_ASPNC;
DR   P28351, AGALA_ASPNG;  Q2UT06, AGALA_ASPOR;  Q0CPK2, AGALA_ASPTN;
DR   A1DDD8, AGALA_NEOFI;  A1C5D3, AGALB_ASPCL;  B0Y224, AGALB_ASPFC;
DR   B8N306, AGALB_ASPFN;  Q4WE86, AGALB_ASPFU;  A2QEJ9, AGALB_ASPNC;
DR   Q9Y865, AGALB_ASPNG;  Q2UJ97, AGALB_ASPOR;  Q5AVQ6, AGALB_EMENI;
DR   A1D0A3, AGALB_NEOFI;  O94221, AGALB_PENSI;  A7XZT2, AGALB_TALEM;
DR   B8NWY6, AGALC_ASPFN;  Q9UUZ4, AGALC_ASPNG;  Q2TW69, AGALC_ASPOR;
DR   Q0CVH2, AGALC_ASPTN;  Q5AU92, AGALC_EMENI;  B0YEK2, AGALD_ASPFC;
DR   B8N7Z0, AGALD_ASPFN;  A4DA70, AGALD_ASPFU;  A2R2S6, AGALD_ASPNC;
DR   Q2UI87, AGALD_ASPOR;  Q0CVX4, AGALD_ASPTN;  Q5AX28, AGALD_EMENI;
DR   A1D9S3, AGALD_NEOFI;  Q0CEF5, AGALG_ASPTN;  Q5ARP5, AGALG_EMENI;
DR   O34645, AGAL_BACSU ;  P86073, AGAL_CAPAA ;  B3PGJ1, AGAL_CELJU ;
DR   Q42656, AGAL_COFAR ;  P14749, AGAL_CYATE ;  Q55B10, AGAL_DICDI ;
DR   P06720, AGAL_ECOLI ;  P06280, AGAL_HUMAN ;  P51569, AGAL_MOUSE ;
DR   Q9FXT4, AGAL_ORYSJ ;  Q9X4Y0, AGAL_RHIME ;  P30877, AGAL_SALTY ;
DR   Q9URZ0, AGAL_SCHPO ;  P27756, AGAL_STRMU ;  Q97U94, AGAL_SULSO ;
DR   B2UL12, GLAA_AKKM8 ;  Q5L7M8, GLAA_BACFN ;  Q64MU6, GLAA_BACFR ;
DR   Q8A2Z5, GLAA_BACTN ;  B1KD83, GLAA_SHEWM ;  Q826C5, GLAA_STRAW ;
DR   B1V8K7, GLAA_STRGU ;  A6KWM0, GLAB1_BACV8;  A6L2M8, GLAB2_BACV8;
DR   B2UNU8, GLAB_AKKM8 ;  Q5LGZ8, GLAB_BACFN ;  Q64XV2, GLAB_BACFR ;
DR   Q89ZX0, GLAB_BACTN ;  A6LFT2, GLAB_PARD8 ;  P04824, MEL1_YEASX ;
DR   P41945, MEL2_YEASX ;  P41946, MEL5_YEASX ;  P41947, MEL6_YEASX ;
DR   Q11129, MEL_SACMI  ;  Q09187, MEL_SACPA  ;  Q03647, MEL_SACPS  ;
DR   Q9UVD6, MEL_TORDE  ;  Q99172, MEL_ZYGCI  ;  Q9P4V4, MEL_ZYGMR  ;
DR   P16551, RAFA_ECOLX ;
//
ID   3.2.1.23
DE   Beta-galactosidase.
AN   Exo-(1->4)-beta-D-galactanase.
AN   Lactase.
CA   Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-
CA   galactosides.
CC   -!- Some enzymes in this group hydrolyze alpha-L-arabinosides; some
CC       animal enzymes also hydrolyze beta-D-fucosides and beta-D-glucosides
CC       (cf. EC 3.2.1.108).
PR   PROSITE; PDOC00495;
PR   PROSITE; PDOC00531;
PR   PROSITE; PDOC00910;
DR   Q9FN08, BGA10_ARATH;  Q67VU7, BGA10_ORYSJ;  Q9SCV1, BGA11_ARATH;
DR   Q6ZJJ0, BGA11_ORYSJ;  Q9SCV0, BGA12_ARATH;  Q0IZZ8, BGA12_ORYSJ;
DR   Q9SCU9, BGA13_ARATH;  Q7G3T8, BGA13_ORYSJ;  Q9SCU8, BGA14_ARATH;
DR   Q7XFK2, BGA14_ORYSJ;  Q9C6W4, BGA15_ARATH;  Q0INM3, BGA15_ORYSJ;
DR   Q8GX69, BGA16_ARATH;  Q93Z24, BGA17_ARATH;  P06864, BGA2_ECOLI ;
DR   Q9SCW1, BGAL1_ARATH;  Q44233, BGAL1_ARTSP;  Q65KX8, BGAL1_BACLD;
DR   O31529, BGAL1_BACSU;  Q54GE1, BGAL1_DICDI;  Q47077, BGAL1_ENTCL;
DR   A6T8X0, BGAL1_KLEP7;  P06219, BGAL1_KLEPN;  Q5FJ41, BGAL1_LACAC;
DR   Q8RUV9, BGAL1_ORYSJ;  Q8GEA9, BGAL1_THESP;  Q9LFA6, BGAL2_ARATH;
DR   C7ASJ5, BGAL2_ARTSP;  Q65CX4, BGAL2_BACLD;  O07012, BGAL2_BACSU;
DR   Q54MV6, BGAL2_DICDI;  Q2XQU3, BGAL2_ENTCL;  A6TI29, BGAL2_KLEP7;
DR   A7KGA5, BGAL2_KLEPN;  C6H178, BGAL2_LACAC;  Q8W0A1, BGAL2_ORYSJ;
DR   O54315, BGAL2_THESP;  Q9SCV9, BGAL3_ARATH;  Q5N8X6, BGAL3_ORYSJ;
DR   Q9SCV8, BGAL4_ARATH;  A2X2H7, BGAL4_ORYSI;  Q6Z6K4, BGAL4_ORYSJ;
DR   Q9MAJ7, BGAL5_ARATH;  Q10RB4, BGAL5_ORYSJ;  Q9FFN4, BGAL6_ARATH;
DR   Q10NX8, BGAL6_ORYSJ;  Q9SCV5, BGAL7_ARATH;  Q75HQ3, BGAL7_ORYSJ;
DR   Q9SCV4, BGAL8_ARATH;  Q0DGD7, BGAL8_ORYSJ;  Q9SCV3, BGAL9_ARATH;
DR   Q5Z7L0, BGAL9_ORYSJ;  B0XMP7, BGALA_ASPFC;  B8N6V7, BGALA_ASPFN;
DR   Q4WS33, BGALA_ASPFU;  A2QAN3, BGALA_ASPNC;  Q2UCU3, BGALA_ASPOR;
DR   Q4ZHV7, BGALA_ASPSA;  Q5BFC4, BGALA_EMENI;  A1D1Z9, BGALA_NEOFI;
DR   B8QGZ3, BGALA_PENEN;  Q700S9, BGALA_PENSQ;  B0XNY2, BGALB_ASPFC;
DR   B8NKI4, BGALB_ASPFN;  Q4WRD3, BGALB_ASPFU;  A2QA64, BGALB_ASPNC;
DR   Q2U6P1, BGALB_ASPOR;  Q0CMF3, BGALB_ASPTN;  A6RPN7, BGALB_BOTFB;
DR   Q5BEQ0, BGALB_EMENI;  A1D199, BGALB_NEOFI;  B6GW04, BGALB_PENCW;
DR   B6QLF0, BGALB_PENMQ;  B2W791, BGALB_PYRTR;  A7EBU5, BGALB_SCLS1;
DR   A1CE56, BGALC_ASPCL;  B0Y752, BGALC_ASPFC;  B8N2I5, BGALC_ASPFN;
DR   Q4WNE4, BGALC_ASPFU;  A2QL84, BGALC_ASPNC;  Q2UMD5, BGALC_ASPOR;
DR   A1DM65, BGALC_NEOFI;  B6H5X9, BGALC_PENCW;  B6QHA9, BGALC_PENMQ;
DR   A7EZS5, BGALC_SCLS1;  B0XXE7, BGALE_ASPFC;  Q4WG05, BGALE_ASPFU;
DR   A1DJ58, BGALE_NEOFI;  P70753, BGAL_ACTPL ;  A0KQH4, BGAL_AERHH ;
DR   C8WV58, BGAL_ALIAD ;  B4S2K9, BGAL_ALTMD ;  Q59140, BGAL_ARTSB ;
DR   P29853, BGAL_ASPNG ;  P45582, BGAL_ASPOF ;  D5JGG0, BGAL_BACCO ;
DR   Q9K9C6, BGAL_BACHD ;  O52847, BGAL_BACMD ;  A1A399, BGAL_BIFAA ;
DR   D4QFE7, BGAL_BIFBI ;  Q93GI5, BGAL_BIFLI ;  Q58D55, BGAL_BOVIN ;
DR   P49676, BGAL_BRAOL ;  Q9TRY9, BGAL_CANFA ;  Q9RFN0, BGAL_CARML ;
DR   A8AKB8, BGAL_CITK8 ;  P24131, BGAL_CLOAB ;  D9SM34, BGAL_CLOC7 ;
DR   Q0TUR6, BGAL_CLOP1 ;  Q00662, BGAL_DIACA ;  A7ZI91, BGAL_ECO24 ;
DR   B7UJI9, BGAL_ECO27 ;  Q8X685, BGAL_ECO57 ;  B5Z2P7, BGAL_ECO5E ;
DR   A7ZWZ1, BGAL_ECOHS ;  A1A831, BGAL_ECOK1 ;  Q0TKT1, BGAL_ECOL5 ;
DR   Q8FKG6, BGAL_ECOL6 ;  B1J0T5, BGAL_ECOLC ;  P00722, BGAL_ECOLI ;
DR   B7N8Q1, BGAL_ECOLU ;  Q8VNN2, BGAL_ECOLX ;  B1LIM9, BGAL_ECOSM ;
DR   Q1RFJ2, BGAL_ECOUT ;  A4W7D2, BGAL_ENT38 ;  A3FEW8, BGAL_ENTAG ;
DR   A7MN76, BGAL_ENTS8 ;  Q6D736, BGAL_ERWCT ;  B2VHN8, BGAL_ERWT9 ;
DR   O19015, BGAL_FELCA ;  P19668, BGAL_GEOKA ;  C9S0R2, BGAL_GEOSY ;
DR   P94804, BGAL_HALL2 ;  P83252, BGAL_HORVU ;  P16278, BGAL_HUMAN ;
DR   B5XQY2, BGAL_KLEP3 ;  P00723, BGAL_KLULA ;  O07684, BGAL_LACAC ;
DR   Q1G9Z4, BGAL_LACDA ;  P0C1Y0, BGAL_LACDE ;  Q7WTB4, BGAL_LACHE ;
DR   Q48727, BGAL_LACLA ;  Q48846, BGAL_LACSK ;  Q02603, BGAL_LEULA ;
DR   Q03WL0, BGAL_LEUMM ;  Q60HF6, BGAL_MACFA ;  P48981, BGAL_MALDO ;
DR   P23780, BGAL_MOUSE ;  Q04F24, BGAL_OENOB ;  P85412, BGAL_PHODC ;
DR   Q6LL68, BGAL_PHOPR ;  P81669, BGAL_PINPS ;  Q09HN2, BGAL_PLASL ;
DR   Q9KI47, BGAL_PLASS ;  Q5R7P4, BGAL_PONAB ;  P81650, BGAL_PSEHA ;
DR   A1SWB8, BGAL_PSYIN ;  O52629, BGAL_PYRWO ;  Q59750, BGAL_RHIME ;
DR   P30812, BGAL_RHIRD ;  A9MQ82, BGAL_SALAR ;  A8GGN3, BGAL_SERP5 ;
DR   Q32JB6, BGAL_SHIDS ;  Q3Z583, BGAL_SHISS ;  P48980, BGAL_SOLLC ;
DR   O33815, BGAL_STAXY ;  P23989, BGAL_STRTR ;  P14288, BGAL_SULAC ;
DR   P50388, BGAL_SULSH ;  P22498, BGAL_SULSO ;  Q9X6C6, BGAL_THEBO ;
DR   Q56307, BGAL_THEMA ;  P77989, BGAL_THEP3 ;  O69315, BGAL_THETH ;
DR   P26257, BGAL_THETU ;  A5F5U6, BGAL_VIBC3 ;  Q8D4H3, BGAL_VIBVU ;
DR   Q7MG04, BGAL_VIBVY ;  P48982, BGAL_XANMN ;  A1JTC4, BGAL_YERE8 ;
DR   A7FH78, BGAL_YERP3 ;  Q1C6T8, BGAL_YERPA ;  B2K6E6, BGAL_YERPB ;
DR   Q7CIZ3, BGAL_YERPE ;  A9R0J8, BGAL_YERPG ;  Q1CI76, BGAL_YERPN ;
DR   A4TLL5, BGAL_YERPP ;  Q669R9, BGAL_YERPS ;  B1JI86, BGAL_YERPY ;
DR   O07685, BGAM_LACAC ;  Q7WTB3, BGAM_LACHE ;  Q48847, BGAM_LACSK ;
DR   Q02604, BGAM_LEULA ;
//
ID   3.2.1.24
DE   Alpha-mannosidase.
CA   Hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-
CA   mannosides.
CC   -!- Also hydrolyzes alpha-D-lyxosides and heptopyranosides with the same
CC       configuration at C-2, C-3 and C-4 as mannose.
DR   Q29451, MA2B1_BOVIN;  Q8VHC8, MA2B1_CAVPO;  O46432, MA2B1_FELCA;
DR   O00754, MA2B1_HUMAN;  Q60HE9, MA2B1_MACFA;  O09159, MA2B1_MOUSE;
DR   Q9Y2E5, MA2B2_HUMAN;  O54782, MA2B2_MOUSE;  Q28949, MA2B2_PIG  ;
DR   Q5RDJ3, MA2B2_PONAB;  Q9NTJ4, MA2C1_HUMAN;  Q91W89, MA2C1_MOUSE;
DR   P21139, MA2C1_RAT  ;  Q9UT61, MAN1_SCHPO ;  P22855, MAN1_YEAST ;
DR   P34098, MANA_DICDI ;  Q54YF7, MANB_DICDI ;  Q55ER0, MANC_DICDI ;
DR   Q54YC4, MAND_DICDI ;  Q1ZXI8, MANE_DICDI ;  Q54KN4, MANF_DICDI ;
DR   Q54K67, MANG_DICDI ;
//
ID   3.2.1.25
DE   Beta-mannosidase.
AN   Mannanase.
AN   Mannase.
CA   Hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-
CA   mannosides.
DR   O74168, MANBA_ASPAC;  A1CTM5, MANBA_ASPCL;  B0Y7S2, MANBA_ASPFC;
DR   B8NP78, MANBA_ASPFN;  Q4WMS9, MANBA_ASPFU;  A2QWU9, MANBA_ASPNC;
DR   Q9UUZ3, MANBA_ASPNG;  Q2UN00, MANBA_ASPOR;  Q0CI48, MANBA_ASPTN;
DR   Q29444, MANBA_BOVIN;  Q93324, MANBA_CAEEL;  Q95327, MANBA_CAPHI;
DR   Q5BCI8, MANBA_EMENI;  O00462, MANBA_HUMAN;  Q8K2I4, MANBA_MOUSE;
DR   A1DMT2, MANBA_NEOFI;  Q4FZV0, MANBA_RAT  ;  A1CGA8, MANBB_ASPCL;
DR   B0YBU9, MANBB_ASPFC;  B8NW36, MANBB_ASPFN;  Q4WAH4, MANBB_ASPFU;
DR   A2QYN2, MANBB_ASPNC;  Q2TXB7, MANBB_ASPOR;  Q0CCA0, MANBB_ASPTN;
DR   Q5B7W2, MANBB_EMENI;  A1D911, MANBB_NEOFI;
//
ID   3.2.1.26
DE   Beta-fructofuranosidase.
AN   Beta-fructosidase.
AN   Invertase.
AN   Saccharase.
CA   Hydrolysis of terminal non-reducing beta-D-fructofuranoside residues in
CA   beta-D-fructofuranosides.
CC   -!- Substrates include sucrose.
CC   -!- Also catalyzes fructotransferase reactions.
PR   PROSITE; PDOC00532;
DR   O33833, BFRA_THEMA ;  P40714, CSCA_ECOLX ;  Q43866, INV1_ARATH ;
DR   P93761, INV1_CAPAN ;  P26792, INV1_DAUCA ;  P40912, INV1_HANAN ;
DR   P49175, INV1_MAIZE ;  A2X5P7, INV1_ORYSI ;  Q0E0P0, INV1_ORYSJ ;
DR   Q43089, INV1_PEA   ;  O59852, INV1_SCHPO ;  P10594, INV1_YEASX ;
DR   Q1PEF8, INV2_ARATH ;  Q39692, INV2_DAUCA ;  Q01IS7, INV2_ORYSI ;
DR   Q0JDC5, INV2_ORYSJ ;  P00724, INV2_YEAST ;  Q39693, INV3_DAUCA ;
DR   Q01IS8, INV3_ORYSI ;  Q0JDC6, INV3_ORYSJ ;  P10595, INV3_YEASX ;
DR   Q8W413, INV4_ARATH ;  Q5JJV0, INV4_ORYSJ ;  P10596, INV4_YEASX ;
DR   Q9LIB9, INV5_ARATH ;  Q56UD1, INV5_ORYSJ ;  P10597, INV5_YEASX ;
DR   Q56UD0, INV6_ORYSJ ;  A2YZ01, INV7_ORYSI ;  Q0J360, INV7_ORYSJ ;
DR   P07635, INV7_YEASX ;  P49174, INVA_MAIZE ;  O24509, INVA_PHAVU ;
DR   P29000, INVA_SOLLC ;  Q43857, INVA_VICFA ;  P29001, INVA_VIGRR ;
DR   P80065, INVB_DAUCA ;  Q60115, INVB_ZYMMO ;  O42878, INVX_SCHPO ;
DR   Q6BJW6, INV_DEBHA  ;  Q9Y746, INV_KLULA  ;  P24133, INV_SCHOC  ;
DR   P16553, RAFD_ECOLX ;  Q9KLT6, SCRB1_VIBCH;  Q56660, SCRB2_VIBCH;
DR   P07819, SCRB_BACSU ;  Q09122, SCRB_FUSMR ;  P27217, SCRB_KLEPN ;
DR   Q04937, SCRB_LACLA ;  P43471, SCRB_PEDPE ;  A1STJ9, SCRB_PSYIN ;
DR   P37075, SCRB_SALTY ;  Q05936, SCRB_STAXY ;  P13522, SCRB_STRMU ;
DR   P13394, SCRB_VIBAL ;  A5EZZ8, SCRB_VIBC3 ;  P35636, SCR_ZYMMO  ;
//
ID   3.2.1.27
DE   Deleted entry.
//
ID   3.2.1.28
DE   Alpha,alpha-trehalase.
AN   Trehalase.
CA   Alpha,alpha-trehalose + H(2)O = 2 D-glucose.
PR   PROSITE; PDOC00717;
DR   P48016, ATH1_YEAST ;  A8J4S9, TREA_APIME ;  P32358, TREA_BOMMO ;
DR   P52494, TREA_CANAL ;  A8AFT6, TREA_CITK8 ;  Q54QZ5, TREA_DICDI ;
DR   Q9W2M2, TREA_DROME ;  A7ZKW9, TREA_ECO24 ;  B7UQ86, TREA_ECO27 ;
DR   B7MK99, TREA_ECO45 ;  B7LGV7, TREA_ECO55 ;  Q8XDH7, TREA_ECO57 ;
DR   B7NUW3, TREA_ECO7I ;  B7LXB1, TREA_ECO8A ;  C4ZTN8, TREA_ECOBW ;
DR   B1XAN8, TREA_ECODH ;  A7ZZD1, TREA_ECOHS ;  A1AAC5, TREA_ECOK1 ;
DR   Q0TIH3, TREA_ECOL5 ;  Q8CW46, TREA_ECOL6 ;  B1IU96, TREA_ECOLC ;
DR   P13482, TREA_ECOLI ;  B7N408, TREA_ECOLU ;  B6I9Q8, TREA_ECOSE ;
DR   B1LHA4, TREA_ECOSM ;  Q1RCP3, TREA_ECOUT ;  P78617, TREA_EMENI ;
DR   O43280, TREA_HUMAN ;  P49381, TREA_KLULA ;  Q9JLT2, TREA_MOUSE ;
DR   Q8MMG9, TREA_PIMHY ;  Q9I165, TREA_PSEAE ;  P19813, TREA_RABIT ;
DR   Q8XT38, TREA_RALSO ;  B5F4F0, TREA_SALA4 ;  Q57NL6, TREA_SALCH ;
DR   B5FTN7, TREA_SALDC ;  B5R2X4, TREA_SALEP ;  B5R904, TREA_SALG2 ;
DR   B4SUI9, TREA_SALNS ;  Q5PI73, TREA_SALPA ;  A9MVX4, TREA_SALPB ;
DR   C0Q337, TREA_SALPC ;  B5BI56, TREA_SALPK ;  B4TXW7, TREA_SALSV ;
DR   P59765, TREA_SALTI ;  Q8ZP20, TREA_SALTY ;  O42893, TREA_SCHPO ;
DR   Q32H09, TREA_SHIDS ;  Q0T5J8, TREA_SHIF8 ;  Q83RP6, TREA_SHIFL ;
DR   P32359, TREA_TENMO ;  Q8PPT1, TREA_XANAC ;  Q4UZ12, TREA_XANC8 ;
DR   B0RNH1, TREA_XANCB ;  Q8P519, TREA_XANCP ;  Q2NYS3, TREA_XANOM ;
DR   P32356, TREA_YEAST ;  Q757L1, TREB_ASHGO ;  O42777, TREB_EMENI ;
DR   O42622, TREB_MAGO7 ;  O42783, TREB_NEUCR ;  P35172, TREB_YEAST ;
DR   A7ZT60, TREF_ECO24 ;  B7UL72, TREF_ECO27 ;  B7MEM1, TREF_ECO45 ;
DR   B7L603, TREF_ECO55 ;  P62602, TREF_ECO57 ;  B5YVG5, TREF_ECO5E ;
DR   B7NNF3, TREF_ECO7I ;  B7N1V9, TREF_ECO81 ;  B7M3D0, TREF_ECO8A ;
DR   C4ZW66, TREF_ECOBW ;  B1X7X4, TREF_ECODH ;  A8A5X9, TREF_ECOHS ;
DR   A1AH61, TREF_ECOK1 ;  Q0TBT4, TREF_ECOL5 ;  Q8FCI4, TREF_ECOL6 ;
DR   B1J0B4, TREF_ECOLC ;  P62601, TREF_ECOLI ;  B7NEG2, TREF_ECOLU ;
DR   B6I385, TREF_ECOSE ;  B1LJ63, TREF_ECOSM ;  Q1R584, TREF_ECOUT ;
DR   B7LSZ0, TREF_ESCF3 ;  B5F9H0, TREF_SALA4 ;  A9MLK7, TREF_SALAR ;
DR   Q57IL9, TREF_SALCH ;  B5FKM4, TREF_SALDC ;  B5R404, TREF_SALEP ;
DR   B5RGS3, TREF_SALG2 ;  B4T8D8, TREF_SALHS ;  B4SWF1, TREF_SALNS ;
DR   C0Q162, TREF_SALPC ;  B4TZ02, TREF_SALSV ;  Q8Z277, TREF_SALTI ;
DR   Q8ZLC8, TREF_SALTY ;  B2U4I7, TREF_SHIB3 ;  Q31VA6, TREF_SHIBS ;
DR   Q0SZB4, TREF_SHIF8 ;  Q83PS8, TREF_SHIFL ;  Q3YWJ3, TREF_SHISS ;
//
ID   3.2.1.29
DE   Transferred entry: 3.2.1.52.
//
ID   3.2.1.30
DE   Transferred entry: 3.2.1.52.
//
ID   3.2.1.31
DE   Beta-glucuronidase.
CA   A beta-D-glucuronoside + H(2)O = D-glucuronate + an alcohol.
PR   PROSITE; PDOC00531;
DR   O18835, BGLR_CANFA ;  O77695, BGLR_CHLAE ;  P05804, BGLR_ECOLI ;
DR   O97524, BGLR_FELCA ;  P08236, BGLR_HUMAN ;  P12265, BGLR_MOUSE ;
DR   Q4FAT7, BGLR_PIG   ;  Q5R5N6, BGLR_PONAB ;  P06760, BGLR_RAT   ;
DR   Q9UEF7, KLOT_HUMAN ;  Q8WP17, KLOT_MACFA ;  O35082, KLOT_MOUSE ;
DR   Q9Z2Y9, KLOT_RAT   ;
//
ID   3.2.1.32
DE   Xylan endo-1,3-beta-xylosidase.
AN   Endo-1,3-beta-xylanase.
AN   Xylanase.
CA   Random hydrolysis of (1->3)-beta-D-glycosidic linkages in (1->3)-beta-D-
CA   xylans.
DR   D5MP61, 3XYN1_VIBSX;  Q9LCB9, 3XYN2_VIBSX;  Q8RS40, 3XYN_ALCSP ;
//
ID   3.2.1.33
DE   Amylo-alpha-1,6-glucosidase.
AN   Amylo-1,6-glucosidase.
AN   Dextrin 6-alpha-D-glucosidase.
CA   Hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen
CA   phosphorylase limit dextrin.
CC   -!- This enzyme hydrolyzes an unsubstituted (1->6)-alpha-glucose residue
CC       that forms a branch point on an alpha-(1->4)-linked glucose chain.
CC   -!- The enzyme activity found in mammals and Saccharomyces cerevisiae is
CC       in a polypeptide chain containing two active centers.
CC   -!- The other activity is similar to that of EC 2.4.1.25, which acts on
CC       the glycogen phosphorylase limit dextrin chains to expose the single
CC       glucose residues, which the 6-alpha-glucosidase activity can then
CC       hydrolyze.
CC   -!- Together, these two activities constitute the glycogen debranching
CC       system.
DR   Q2PQH8, GDE_CANFA  ;  A8BQB4, GDE_HORSE  ;  P35573, GDE_HUMAN  ;
DR   P35574, GDE_RABIT  ;  Q06625, GDE_YEAST  ;
//
ID   3.2.1.34
DE   Transferred entry: 3.2.1.35.
//
ID   3.2.1.35
DE   Hyaluronoglucosaminidase.
AN   Chondroitinase.
AN   Chondroitinase I.
AN   Hyaluronidase.
AN   Hyaluronoglucosidase.
CA   Random hydrolysis of (1->4)-linkages between N-acetyl-beta-D-glucosamine
CA   and D-glucuronate residues in hyaluronate.
CC   -!- Also hydrolyzes 1,4-beta-D-glycosidic linkages between N-acetyl-
CC       galactosamine or N-acetylgalactosamine sulfate and glucuronic acid in
CC       chondroitin, chondroitin 4- and 6-sulfates, and dermatan.
CC   -!- Formerly EC 3.2.1.34.
DR   P50828, HEMO_PIG   ;  P49370, HUGAA_VESVU;  Q08169, HUGA_APIME ;
DR   P49371, HUGA_DOLMA ;  P86274, HUGA_PHOKE ;  Q9U6V9, HUGA_POLAN ;
DR   P86687, HUGA_POLPI ;  P85841, HUGA_TITSE ;  P0CH89, HUGA_VESMC ;
DR   P86875, HUGA_VESMG ;  Q5E985, HYAL1_BOVIN;  Q12794, HYAL1_HUMAN;
DR   P86100, HYAL1_MESMA;  Q91ZJ9, HYAL1_MOUSE;  Q6RHW4, HYAL1_PIG  ;
DR   Q76HN1, HYAL1_RAT  ;  Q8SQG8, HYAL2_BOVIN;  Q12891, HYAL2_HUMAN;
DR   O35632, HYAL2_MOUSE;  Q9Z2Q3, HYAL2_RAT  ;  Q8SQG7, HYAL2_SHEEP;
DR   O43820, HYAL3_HUMAN;  Q8VEI3, HYAL3_MOUSE;  Q6RHW2, HYAL3_PIG  ;
DR   Q5REQ1, HYAL3_PONAB;  Q76HM9, HYAL3_RAT  ;  Q2M3T9, HYAL4_HUMAN;
DR   Q05A56, HYAL4_MOUSE;  P23613, HYALP_CAVPO;  P38567, HYALP_HUMAN;
DR   P38568, HYALP_MACFA;  P48794, HYALP_MOUSE;  P38566, HYALP_RABIT;
DR   Q62803, HYALP_RAT  ;  P0C8X3, HYAL_TITST ;  P15316, HYLP1_BPH44;
DR   Q54699, HYLP2_BPH45;  P26831, NAGH_CLOPE ;
//
ID   3.2.1.36
DE   Hyaluronoglucuronidase.
AN   Hyaluronidase.
CA   Random hydrolysis of (1->3)-linkages between beta-D-glucuronate and
CA   N-acetyl-D-glucosamine residues in hyaluronate.
//
ID   3.2.1.37
DE   Xylan 1,4-beta-xylosidase.
AN   1,4-beta-D-xylan xylohydrolase.
AN   Beta-xylosidase.
AN   Exo-1,4-beta-xylosidase.
AN   Xylobiase.
CA   Hydrolysis of (1->4)-beta-D-xylans, to remove successive D-xylose
CA   residues from the non-reducing termini.
CC   -!- Also hydrolyzes xylobiose.
CC   -!- Some other exoglycosidase activities have been found associated with
CC       this enzyme in sheep liver.
PR   PROSITE; PDOC00787;
DR   Q46684, BGLX_ERWCH ;  Q9FLG1, BXL4_ARATH ;  A1CCL9, BXLB_ASPCL ;
DR   B0Y0I4, BXLB_ASPFC ;  B8NYD8, BXLB_ASPFN ;  Q4WFI6, BXLB_ASPFU ;
DR   Q2TYT2, BXLB_ASPOR ;  Q0CB82, BXLB_ASPTN ;  Q5ATH9, BXLB_EMENI ;
DR   P86450, XYL1_MEDSA ;  A5JTQ2, XYL1_MEDSV ;  P48792, XYL1_TRIKO ;
DR   A5JTQ3, XYL2_MEDSV ;  P45702, XYLA1_GEOSE;  P45704, XYLA2_GEOSE;
DR   P48790, XYLA_CLOSR ;  P49943, XYLB_BACOV ;  P45982, XYLB_BUTFI ;
DR   Q9WXE8, XYLO_PRERU ;  P07129, XYNB_BACPU ;  P94489, XYNB_BACSU ;
DR   P23552, XYNB_CALSA ;  Q9ZFM2, XYNB_GEOSE ;  P48791, XYNB_PRERU ;
DR   P36906, XYNB_THESA ;  O30360, XYNB_THESJ ;  C0STH4, XYND_ASPAC ;
DR   Q4AEG8, XYND_ASPAW ;  A1CND4, XYND_ASPCL ;  B0XP71, XYND_ASPFC ;
DR   B8MYV0, XYND_ASPFN ;  Q4WRB0, XYND_ASPFU ;  B6EY09, XYND_ASPJA ;
DR   A2QA27, XYND_ASPNC ;  O00089, XYND_ASPNG ;  Q2UR38, XYND_ASPOR ;
DR   Q0CMH8, XYND_ASPTN ;  Q5BAS1, XYND_EMENI ;  A1DJS5, XYND_NEOFI ;
DR   P77713, YAGH_ECOLI ;
//
ID   3.2.1.38
DE   Beta-D-fucosidase.
CA   Hydrolysis of terminal non-reducing beta-D-fucose residues in beta-D-
CA   fucosides.
CC   -!- Enzymes from some sources also hydrolyze beta-D-galactosides and/or
CC       beta-D-glucosides and/or alpha-L-arabinosides.
CC   -!- The activity of EC 3.2.1.37 is an associated activity found in some
CC       sources (e.g. liver).
DR   P94248, BGLFU_BIFBR;
//
ID   3.2.1.39
DE   Glucan endo-1,3-beta-D-glucosidase.
AN   (1->3)-beta-glucan endohydrolase.
AN   Endo-1,3-beta-glucanase.
AN   Laminarinase.
CA   Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.
CC   -!- Very limited action on mixed-link (1->3,1->4)-beta-D-glucans.
CC   -!- Hydrolyzes laminarin, paramylon and pachyman.
CC   -!- Different from EC 3.2.1.6.
PR   PROSITE; PDOC00507;
PR   PROSITE; PDOC00794;
DR   A1CAI0, BTGC_ASPCL ;  B0Y429, BTGC_ASPFC ;  B8NTP7, BTGC_ASPFN ;
DR   Q4WUK5, BTGC_ASPFU ;  A2QN74, BTGC_ASPNC ;  Q2U492, BTGC_ASPOR ;
DR   Q0CI96, BTGC_ASPTN ;  Q5B430, BTGC_EMENI ;  A1DEV5, BTGC_NEOFI ;
DR   Q9FHX5, E1310_ARATH;  Q8L868, E1311_ARATH;  Q8VYE5, E1312_ARATH;
DR   Q9FJU9, E1313_ARATH;  Q9ZQG9, E1314_ARATH;  O65399, E131_ARATH ;
DR   P52400, E131_SOLTU ;  Q9C7U5, E132_ARATH ;  P52401, E132_SOLTU ;
DR   Q9ZU91, E133_ARATH ;  P52402, E133_SOLTU ;  Q94CD8, E134_ARATH ;
DR   Q9M088, E135_ARATH ;  Q93Z08, E136_ARATH ;  Q9M069, E137_ARATH ;
DR   Q6NKW9, E138_ARATH ;  Q9FGH4, E139_ARATH ;  P33157, E13A_ARATH ;
DR   P34742, E13A_HORVU ;  Q01412, E13A_SOLLC ;  Q03773, E13A_SOYBN ;
DR   P85203, E13B1_CRYLA;  P85238, E13B2_CRYLA;  Q59146, E13B_ARTSW ;
DR   P23903, E13B_BACCI ;  P49236, E13B_BRACM ;  P86080, E13B_CAPAA ;
DR   P22222, E13B_CELCE ;  P52407, E13B_HEVBR ;  P15737, E13B_HORVU ;
DR   P49237, E13B_MAIZE ;  P23431, E13B_NICPL ;  Q03467, E13B_PEA   ;
DR   P23535, E13B_PHAVU ;  P85483, E13B_PINHA ;  P52408, E13B_PRUPE ;
DR   Q01413, E13B_SOLLC ;  P52395, E13B_SOYBN ;  P15797, E13B_TOBAC ;
DR   P53626, E13B_TRIHA ;  P86102, E13B_VITRO ;  A7PQW3, E13B_VITVI ;
DR   P52409, E13B_WHEAT ;  Q02126, E13C_HORVU ;  P23432, E13C_TOBAC ;
DR   Q02437, E13D_HORVU ;  P23433, E13D_TOBAC ;  Q02438, E13E_HORVU ;
DR   P23546, E13E_TOBAC ;  Q02439, E13F_HORVU ;  P27666, E13F_TOBAC ;
DR   P23547, E13G_TOBAC ;  P36401, E13H_TOBAC ;  P52396, E13I_TOBAC ;
DR   P52397, E13J_TOBAC ;  P52398, E13K_TOBAC ;  P52399, E13L_TOBAC ;
DR   Q06915, EA6_ARATH  ;  A1CD22, EGLC_ASPCL ;  B0XXF8, EGLC_ASPFC ;
DR   Q4WG16, EGLC_ASPFU ;  A2QH21, EGLC_ASPNC ;  Q2UUZ1, EGLC_ASPOR ;
DR   Q0C7P6, EGLC_ASPTN ;  Q5AUT0, EGLC_EMENI ;  A1DJ47, EGLC_NEOFI ;
DR   P50694, TLP_PRUAV  ;
//
ID   3.2.1.40
DE   Alpha-L-rhamnosidase.
CA   Hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-
CA   rhamnosides.
//
ID   3.2.1.41
DE   Pullulanase.
AN   Alpha-dextrin endo-1,6-alpha-glucosidase.
AN   Amylopectin 6-glucanohydrolase.
AN   Debranching enzyme.
AN   Limit dextrinase.
AN   Pullulan 6-glucanohydrolase.
CA   Hydrolysis of (1->6)-alpha-D-glucosidic linkages in pullulan, amylopectin
CA   and glycogen, and in the alpha- and beta-limit dextrins of amylopectin
CA   and glycogen.
CC   -!- Different from EC 3.2.1.142 in its action on glycogen, and its rate
CC       of hydrolysis of limit dextrins.
CC   -!- Its action on amylopectin is complete.
CC   -!- Maltose is the smallest sugar that it can release from an alpha-
CC       (1->6)-linkage.
CC   -!- Formerly EC 3.2.1.69.
DR   P38939, APU_THEP3  ;  P36905, APU_THESA  ;  P38536, APU_THETU  ;
DR   P16950, APU_THETY  ;  C0SPA0, PULA_BACSU ;  P07811, PULA_ENTAE ;
DR   P07206, PULA_KLEPN ;  O33840, PULA_THEMA ;
//
ID   3.2.1.42
DE   GDP-glucosidase.
CA   GDP-glucose + H(2)O = D-glucose + GDP.
//
ID   3.2.1.43
DE   Beta-L-rhamnosidase.
CA   Hydrolysis of terminal, non-reducing beta-L-rhamnose residues in beta-L-
CA   rhamnosides.
//
ID   3.2.1.44
DE   Fucoidanase.
CA   Endohydrolysis of (1->2)-alpha-L-fucoside linkages in fucoidan without
CA   release of sulfate.
//
ID   3.2.1.45
DE   Glucosylceramidase.
AN   Acid beta-glucosidase.
AN   Beta-glucocerebrosidase.
AN   D-glucosyl-N-acylsphingosine glucohydrolase.
CA   D-glucosyl-N-acylsphingosine + H(2)O = D-glucose + N-acylsphingosine.
CC   -!- Also acts on glucosylsphingosine (cf. EC 3.2.1.62).
DR   Q7KT91, C3390_DROME;  Q9HCG7, GBA2_HUMAN ;  Q69ZF3, GBA2_MOUSE ;
DR   Q5M868, GBA2_RAT   ;  Q2KHZ8, GLCM_BOVIN ;  P04062, GLCM_HUMAN ;
DR   P17439, GLCM_MOUSE ;  Q9BDT0, GLCM_PANTR ;  Q70KH2, GLCM_PIG   ;
DR   Q5R8E3, GLCM_PONAB ;
//
ID   3.2.1.46
DE   Galactosylceramidase.
AN   Galactocerebrosidase.
AN   Galactocerebroside beta-galactosidase.
AN   Galactosylceramide beta-galactosidase.
AN   Galcerase.
CA   D-galactosyl-N-acylsphingosine + H(2)O = D-galactose + N-acylsphingosine.
CC   -!- Cf. EC 3.2.1.62.
DR   Q95QT2, GALC_CAEEL ;  P54804, GALC_CANFA ;  Q5SNX7, GALC_DANRE ;
DR   P54803, GALC_HUMAN ;  O02791, GALC_MACMU ;  P54818, GALC_MOUSE ;
DR   B5X3C1, GALC_SALSA ;  Q498K0, GALC_XENLA ;  Q0VA39, GALC_XENTR ;
//
ID   3.2.1.47
DE   Galactosylgalactosylglucosylceramidase.
CA   D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine + H(2)O =
CA   D-galactose + lactosyl-N-acylsphingosine.
//
ID   3.2.1.48
DE   Sucrose alpha-glucosidase.
AN   Sucrase.
AN   Sucrase-isomaltase.
AN   Sucrose alpha-glucohydrolase.
CA   Hydrolysis of sucrose and maltose by an alpha-D-glucosidase-type action.
CC   -!- Isolated from intestinal mucosa as a single polypeptide chain also
CC       displaying activity toward isomaltose (EC 3.2.1.10).
PR   PROSITE; PDOC00120;
DR   P14410, SUIS_HUMAN ;  P56729, SUIS_PIG   ;  P07768, SUIS_RABIT ;
DR   P23739, SUIS_RAT   ;  O62653, SUIS_SUNMU ;
//
ID   3.2.1.49
DE   Alpha-N-acetylgalactosaminidase.
AN   Alpha-galactosidase B.
AN   Alpha-NAGA.
CA   Hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in
CA   N-acetyl-alpha-D-galactosaminides.
CC   -!- Splits N-acetylgalactosaminyl groups from O-3 of Ser and Thr.
PR   PROSITE; PDOC00443;
DR   Q5LGW9, G1092_BACFN;  A4Q8G1, GH109_BACFO;  A4Q8F7, GH109_FLAME;
DR   Q8ECL7, GH109_SHEON;  P83127, NAGAB_BOSIN;  Q58DH9, NAGAB_BOVIN;
DR   Q90744, NAGAB_CHICK;  P17050, NAGAB_HUMAN;  Q9QWR8, NAGAB_MOUSE;
DR   Q66H12, NAGAB_RAT  ;
//
ID   3.2.1.50
DE   Alpha-N-acetylglucosaminidase.
AN   N-acetyl-alpha-glucosaminidase.
AN   NAG.
CA   Hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in
CA   N-acetyl-alpha-D-glucosaminides.
CC   -!- Hydrolyzes UDP-N-acetylglucosamine.
DR   P54802, ANAG_HUMAN ;
//
ID   3.2.1.51
DE   Alpha-L-fucosidase.
AN   Alpha-L-fucoside fucohydrolase.
CA   An alpha-L-fucoside + H(2)O = L-fucose + an alcohol.
PR   PROSITE; PDOC00324;
DR   A2R797, AFCA_ASPNC ;  Q2USL3, AFCA_ASPOR ;  Q5AU81, AFCA_EMENI ;
DR   Q8GW72, FUCO1_ARATH;  Q7XUR3, FUCO1_ORYSJ;  Q8L7W8, FUCO2_ARATH;
DR   Q9BTY2, FUCO2_HUMAN;  Q99KR8, FUCO2_MOUSE;  Q5RFI5, FUCO2_PONAB;
DR   Q6AYS4, FUCO2_RAT  ;  Q9FXE5, FUCO3_ARATH;  Q2KIM0, FUCO_BOVIN ;
DR   C3YWU0, FUCO_BRAFL ;  P49713, FUCO_CAEEL ;  P48300, FUCO_CANFA ;
DR   P10901, FUCO_DICDI ;  Q9VTJ4, FUCO_DROME ;  P04066, FUCO_HUMAN ;
DR   Q60HF8, FUCO_MACFA ;  Q99LJ1, FUCO_MOUSE ;  P17164, FUCO_RAT   ;
//
ID   3.2.1.52
DE   Beta-N-acetylhexosaminidase.
AN   Beta-hexosaminidase.
AN   Hexosaminidase.
AN   N-acetyl-beta-glucosaminidase.
CA   Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in
CA   N-acetyl-beta-D-hexosaminides.
CC   -!- Acts on N-acetylglucosides and N-acetylgalactosides.
CC   -!- Formerly EC 3.2.1.29 and EC 3.2.1.30.
DR   Q54468, CHB_SERMA  ;  P13670, CHB_VIBHA  ;  Q8WSF3, FDL_DROME  ;
DR   P43077, HEX1_CANAL ;  P96155, HEX1_VIBFU ;  Q7WUL4, HEX20_CELFI;
DR   P13723, HEXA1_DICDI;  Q54SC9, HEXA2_DICDI;  Q0V8R6, HEXA_BOVIN ;
DR   Q619W7, HEXA_CAEBR ;  Q22492, HEXA_CAEEL ;  P49009, HEXA_ENTHI ;
DR   P06865, HEXA_HUMAN ;  P29416, HEXA_MOUSE ;  Q5RC84, HEXA_PONAB ;
DR   P49008, HEXA_PORGI ;  P48823, HEXA_PSEO7 ;  Q641X3, HEXA_RAT   ;
DR   Q54K55, HEXB1_DICDI;  Q54K56, HEXB2_DICDI;  Q86M34, HEXB_ENTHI ;
DR   P49614, HEXB_FELCA ;  P07686, HEXB_HUMAN ;  P20060, HEXB_MOUSE ;
DR   Q29548, HEXB_PIG   ;  P49007, HEXB_PSEO7 ;  Q6AXR4, HEXB_RAT   ;
DR   P49010, HEXC_BOMMO ;  A6QNR0, HEXDC_BOVIN;  Q8WVB3, HEXDC_HUMAN;
DR   Q3U4H6, HEXDC_MOUSE;  Q04786, HEX_VIBVU  ;  Q7WUL3, NAG3_CELFI ;
DR   A3N1B7, NAGZ_ACTP2 ;  B3GXZ7, NAGZ_ACTP7 ;  B0BQ51, NAGZ_ACTPJ ;
DR   A6VKU4, NAGZ_ACTSZ ;  Q0A911, NAGZ_ALHEH ;  Q5P081, NAGZ_AROAE ;
DR   Q2KXM7, NAGZ_BORA1 ;  Q7WH65, NAGZ_BORBR ;  Q7W9J5, NAGZ_BORPA ;
DR   Q7VWV8, NAGZ_BORPE ;  Q7NWB7, NAGZ_CHRVO ;  A7ZKL1, NAGZ_ECO24 ;
DR   B7UPC3, NAGZ_ECO27 ;  B7MJ94, NAGZ_ECO45 ;  B7LG40, NAGZ_ECO55 ;
DR   P58067, NAGZ_ECO57 ;  B5YVX6, NAGZ_ECO5E ;  B7NKH2, NAGZ_ECO7I ;
DR   B7MTN7, NAGZ_ECO81 ;  B7LX41, NAGZ_ECO8A ;  C4ZS47, NAGZ_ECOBW ;
DR   B1XA17, NAGZ_ECODH ;  A7ZZ65, NAGZ_ECOHS ;  A1AA01, NAGZ_ECOK1 ;
DR   Q8FIN2, NAGZ_ECOL6 ;  B1IUF8, NAGZ_ECOLC ;  P75949, NAGZ_ECOLI ;
DR   B7NAY5, NAGZ_ECOLU ;  B6I9I5, NAGZ_ECOSE ;  B1LI37, NAGZ_ECOSM ;
DR   Q1RD47, NAGZ_ECOUT ;  C5BFM6, NAGZ_EDWI9 ;  A7MFT1, NAGZ_ENTS8 ;
DR   Q6D674, NAGZ_ERWCT ;  B2VDM3, NAGZ_ERWT9 ;  B7LT32, NAGZ_ESCF3 ;
DR   Q7VNI8, NAGZ_HAEDU ;  Q4QLU8, NAGZ_HAEI8 ;  A5UDA9, NAGZ_HAEIE ;
DR   P44955, NAGZ_HAEIN ;  B8F5N0, NAGZ_HAEPS ;  Q0I414, NAGZ_HAES1 ;
DR   B0UTC6, NAGZ_HAES2 ;  Q5QUZ5, NAGZ_IDILO ;  B5XXG4, NAGZ_KLEP3 ;
DR   Q65VK7, NAGZ_MANSM ;  Q606N2, NAGZ_METCA ;  Q1H075, NAGZ_METFK ;
DR   Q5FA94, NAGZ_NEIG1 ;  B4RQ67, NAGZ_NEIG2 ;  A9M1Z4, NAGZ_NEIM0 ;
DR   Q9JVT3, NAGZ_NEIMA ;  Q9K0Q4, NAGZ_NEIMB ;  A1KSD9, NAGZ_NEIMF ;
DR   Q0AF74, NAGZ_NITEC ;  Q82SJ8, NAGZ_NITEU ;  Q2Y863, NAGZ_NITMU ;
DR   Q3J953, NAGZ_NITOC ;  Q9CPH0, NAGZ_PASMU ;  C6DKR8, NAGZ_PECCP ;
DR   Q7N397, NAGZ_PHOLL ;  Q6LJ30, NAGZ_PHOPR ;  B4EVE7, NAGZ_PROMH ;
DR   B7UYS5, NAGZ_PSEA8 ;  Q02PG9, NAGZ_PSEAB ;  Q9HZK0, NAGZ_PSEAE ;
DR   A1SW90, NAGZ_PSYIN ;  B5F8E5, NAGZ_SALA4 ;  Q57QE6, NAGZ_SALCH ;
DR   B5FK98, NAGZ_SALDC ;  B5QXC7, NAGZ_SALEP ;  B5RB93, NAGZ_SALG2 ;
DR   B4TFI4, NAGZ_SALHS ;  B4T3P6, NAGZ_SALNS ;  Q5PGT0, NAGZ_SALPA ;
DR   A9N5J6, NAGZ_SALPB ;  B4TTH9, NAGZ_SALSV ;  Q8Z7I6, NAGZ_SALTI ;
DR   Q8ZQ06, NAGZ_SALTY ;  Q080R9, NAGZ_SHEFN ;  Q8EEW2, NAGZ_SHEON ;
DR   A0KXK3, NAGZ_SHESA ;  Q0HJG7, NAGZ_SHESM ;  Q0HVQ8, NAGZ_SHESR ;
DR   B2U513, NAGZ_SHIB3 ;  Q31ZG4, NAGZ_SHIBS ;  Q32EW7, NAGZ_SHIDS ;
DR   Q7UCW4, NAGZ_SHIFL ;  Q3Z310, NAGZ_SHISS ;  B4SRK3, NAGZ_STRM5 ;
DR   B2FPW9, NAGZ_STRMK ;  Q31G32, NAGZ_THICR ;  Q3SKU2, NAGZ_THIDA ;
DR   B8GSD2, NAGZ_THISH ;  C4LEY6, NAGZ_TOLAT ;  A5F8Y1, NAGZ_VIBC3 ;
DR   Q9KU37, NAGZ_VIBCH ;  C3LSU7, NAGZ_VIBCM ;  P96157, NAGZ_VIBFU ;
DR   Q8PMU1, NAGZ_XANAC ;  Q3BVU6, NAGZ_XANC5 ;  Q4USG7, NAGZ_XANC8 ;
DR   B0RX17, NAGZ_XANCB ;  Q8PB42, NAGZ_XANCP ;  Q2P4L0, NAGZ_XANOM ;
DR   Q5H1Q0, NAGZ_XANOR ;  B2I6G9, NAGZ_XYLF2 ;  Q9PAZ0, NAGZ_XYLFA ;
DR   B0U3L0, NAGZ_XYLFM ;  Q87BR5, NAGZ_XYLFT ;  A1JME4, NAGZ_YERE8 ;
DR   A7FH41, NAGZ_YERP3 ;  B2K731, NAGZ_YERPB ;  Q8ZFS3, NAGZ_YERPE ;
DR   Q669N5, NAGZ_YERPS ;  B1JI47, NAGZ_YERPY ;  P85512, NAHA1_PALCA;
DR   Q8VIJ5, NCOAT_RAT  ;  P49610, STRH_STRPN ;
//
ID   3.2.1.53
DE   Beta-N-acetylgalactosaminidase.
CA   Hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in
CA   N-acetyl-beta-D-galactosaminides.
//
ID   3.2.1.54
DE   Cyclomaltodextrinase.
CA   Cyclomaltodextrin + H(2)O = linear maltodextrin.
CC   -!- Also hydrolyzes linear maltodextrin.
CC   -!- Formerly EC 3.2.1.12 and EC 3.2.1.13.
DR   Q08341, CDAS_LYSSH ;  P29964, CDAS_THEP3 ;
//
ID   3.2.1.55
DE   Alpha-N-arabinofuranosidase.
AN   Alpha-L-arabinofuranosidase.
AN   Arabinofuranosidase.
AN   Arabinosidase.
CA   Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in
CA   alpha-L-arabinosides.
CC   -!- Acts on alpha-L-arabinofuranosides, alpha-L-arabinans containing
CC       (1,3)- and/or (1,5)-linkages, arabinoxylans and arabinogalactans.
CC   -!- Some EC 3.2.1.23 and EC 3.2.1.38 enzymes also hydrolyze alpha-L-
CC       arabinosides.
CC   -!- Formerly EC 3.2.1.79.
PR   PROSITE; PDOC51175;
DR   P82593, ABF1_STRCX ;  Q92455, ABF1_TRIRE ;  Q59219, ABF2_BACOV ;
DR   P94552, ABF2_BACSU ;  P82594, ABF2_STRCX ;  Q96X54, ABFA_ASPAW ;
DR   B8NKA3, ABFA_ASPFN ;  Q8NK90, ABFA_ASPKA ;  A2Q7E0, ABFA_ASPNC ;
DR   P42254, ABFA_ASPNG ;  Q2U790, ABFA_ASPOR ;  Q0CTV2, ABFA_ASPTN ;
DR   Q9KBR4, ABFA_BACHD ;  P94531, ABFA_BACSU ;  Q5BA89, ABFA_EMENI ;
DR   Q9XBQ3, ABFA_GEOSE ;  P53627, ABFA_STRLI ;  Q9C4B1, ABFB_ASPAW ;
DR   A1CGD1, ABFB_ASPCL ;  B8N7I7, ABFB_ASPFN ;  Q4WL66, ABFB_ASPFU ;
DR   Q8NK89, ABFB_ASPKA ;  A2R511, ABFB_ASPNC ;  P42255, ABFB_ASPNG ;
DR   Q2UIM2, ABFB_ASPOR ;  Q0CEE5, ABFB_ASPTN ;  O74288, ABFB_EMENI ;
DR   O54161, ABFB_STRCO ;  P96463, ABFB_STRLI ;  A1CQC3, ABFC_ASPCL ;
DR   B0XQB2, ABFC_ASPFC ;  B8NIX4, ABFC_ASPFN ;  Q4WTB3, ABFC_ASPFU ;
DR   A2QQ94, ABFC_ASPNC ;  Q0D1I6, ABFC_ASPTN ;  Q5BDV3, ABFC_EMENI ;
DR   Q9SG80, ASD1_ARATH ;  Q8VZR2, ASD2_ARATH ;  Q5B9Z8, AXHA1_EMENI;
DR   Q5AUX2, AXHA2_EMENI;  A2QFV9, AXHA_ASPNC ;  P79019, AXHA_ASPNG ;
DR   Q2U7D2, AXHA_ASPOR ;  Q9UVX6, AXHA_ASPSO ;  Q0C8B3, AXHA_ASPTN ;
DR   P79021, AXHA_ASPTU ;  Q9FGY1, BXL1_ARATH ;  Q9LXD6, BXL3_ARATH ;
DR   P86450, XYL1_MEDSA ;  A5JTQ2, XYL1_MEDSV ;  P48792, XYL1_TRIKO ;
DR   A5JTQ3, XYL2_MEDSV ;  P48790, XYLA_CLOSR ;  P49943, XYLB_BACOV ;
DR   P45982, XYLB_BUTFI ;  P23031, XYNC_CELJU ;  Q45071, XYND_BACSU ;
DR   P45796, XYND_PAEPO ;
//
ID   3.2.1.56
DE   Glucuronosyl-disulfoglucosamine glucuronidase.
CA   3-D-glucuronosyl-N(2),6-disulfo-beta-D-glucosamine + H(2)O =
CA   D-glucuronate + N(2),6-disulfo-D-glucosamine.
//
ID   3.2.1.57
DE   Isopullulanase.
CA   Hydrolysis of pullulan to isopanose (6-alpha-maltosylglucose).
CC   -!- The enzyme has practically no action on starch.
CC   -!- Panose (4-alpha-isomaltosylglucose) is hydrolyzed to isomaltose and
CC       glucose.
CC   -!- Cf. EC 3.2.1.41 and EC 3.2.1.135.
DR   O00105, IPUA_ASPNG ;
//
ID   3.2.1.58
DE   Glucan 1,3-beta-glucosidase.
AN   Exo-1,3-beta-glucanase.
AN   Exo-1,3-beta-glucosidase.
CA   Successive hydrolysis of beta-D-glucose units from the non-reducing ends
CA   of (1->3)-beta-D-glucans, releasing alpha-glucose.
CC   -!- Acts on oligosaccharides, but very slowly on laminaribiose.
PR   PROSITE; PDOC00507;
PR   PROSITE; PDOC00565;
DR   P43070, BGL2_CANAL ;  O13990, BGL2_SCHPO ;  P15703, BGL2_YEAST ;
DR   P49426, EXG1_COCCA ;  O93939, EXG1_HANAN ;  Q9URU6, EXG1_SCHPO ;
DR   P23776, EXG1_YEAST ;  O93983, EXG2_HANAN ;  Q10444, EXG2_SCHPO ;
DR   P52911, EXG2_YEAST ;  O74799, EXG3_SCHPO ;  A1CRV0, EXGA_ASPCL ;
DR   B0XN12, EXGA_ASPFC ;  B8N151, EXGA_ASPFN ;  Q4WK60, EXGA_ASPFU ;
DR   A2RAR6, EXGA_ASPNC ;  Q7Z9L3, EXGA_ASPOR ;  Q0CR35, EXGA_ASPTN ;
DR   Q5B5X8, EXGA_EMENI ;  A1D4Q5, EXGA_NEOFI ;  A1CTI3, EXGD_ASPCL ;
DR   B0Y7W2, EXGD_ASPFC ;  B8NNK9, EXGD_ASPFN ;  Q4WMP0, EXGD_ASPFU ;
DR   A2QX52, EXGD_ASPNC ;  Q2UMV7, EXGD_ASPOR ;  Q0CHZ8, EXGD_ASPTN ;
DR   Q5AVZ7, EXGD_EMENI ;  A1DMX4, EXGD_NEOFI ;  Q96V64, EXG_BLUGR  ;
DR   P29717, EXG_CANAL  ;  Q8NKF9, EXG_CANOL  ;  Q12628, EXG_KLULA  ;
DR   Q12626, EXG_PICAN  ;  P85924, EXG_PSEMZ  ;  Q876J3, EXG_SACBA  ;
DR   Q875R9, EXG_SACKL  ;  Q12700, EXG_SCHOC  ;  Q12725, EXG_YARLI  ;
DR   Q876J2, SPR1_SACBA ;  P32603, SPR1_YEAST ;
//
ID   3.2.1.59
DE   Glucan endo-1,3-alpha-glucosidase.
AN   Endo-1,3-alpha-glucanase.
CA   Endohydrolysis of (1->3)-alpha-D-glucosidic linkages in isolichenin,
CA   pseudonigeran and nigeran.
CC   -!- Products from pseudonigeran (1,3-alpha-D-glucan) are nigerose and
CC       alpha-D-glucose.
DR   O13716, AGN1_SCHPO ;  O94510, AGN2_SCHPO ;
//
ID   3.2.1.60
DE   Glucan 1,4-alpha-maltotetraohydrolase.
AN   Exo-maltotetraohydrolase.
AN   G4-amylase.
AN   Glucan 1,4-alpha-maltotetrahydrolase.
AN   Maltotetraose-forming amylase.
CA   Hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous
CA   polysaccharides, to remove successive maltotetraose residues from the
CA   non-reducing chain ends.
CC   -!- Compare EC 3.2.1.2, which removes successive maltose residues,
CC       and EC 3.2.1.98 and EC 3.2.1.116.
PR   PROSITE; PDOC51166;
DR   P22963, AMT4_PSESA ;  P13507, AMT4_PSEST ;
//
ID   3.2.1.61
DE   Mycodextranase.
CA   Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in alpha-D-glucans
CA   containing both (1->3)- and (1->4)-bonds.
CC   -!- Products are nigerose and 4-alpha-D-nigerosylglucose.
CC   -!- No hydrolysis of alpha-D-glucans containing only 1,3- or 1,4-bonds.
//
ID   3.2.1.62
DE   Glycosylceramidase.
AN   Phloretin-glucosidase.
AN   Phlorizin hydrolase.
CA   Glycosyl-N-acylsphingosine + H(2)O = N-acylsphingosine + a sugar.
CC   -!- Broad specificity (cf. EC 3.2.1.45 and EC 3.2.1.46).
CC   -!- Also hydrolyzes phlorizin to phloretin and glucose.
CC   -!- The intestinal enzyme is a complex which also catalyzes the reaction
CC       of EC 3.2.1.108.
PR   PROSITE; PDOC00495;
DR   P09848, LPH_HUMAN  ;  P09849, LPH_RABIT  ;  Q02401, LPH_RAT    ;
//
ID   3.2.1.63
DE   1,2-alpha-L-fucosidase.
AN   Almond emulsin fucosidase II.
CA   Methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside + H(2)O = L-fucose +
CA   methyl beta-D-galactoside.
CC   -!- Highly specific for non-reducing terminal L-fucose residues linked to
CC       D-galactose residues by 1,2-alpha-linkage.
CC   -!- Not identical with EC 3.2.1.111.
//
ID   3.2.1.64
DE   2,6-beta-fructan 6-levanbiohydrolase.
AN   2,6-beta-D-fructan 6-beta-D-fructofuranosylfructohydrolase.
AN   2,6-beta-D-fructan 6-levanbiohydrolase.
AN   Beta-2,6-fructan-6-levanbiohydrolase.
AN   Levanbiose-producing levanase.
CA   Hydrolysis of (2->6)-beta-D-fructofuranan, to remove successive
CA   disaccharide residues as levanbiose, i.e. 6-(beta-D-fructofuranosyl)-D-
CA   fructose, from the end of the chain.
DR   O07003, LEVB_BACSU ;  P94469, LEVB_GEOSE ;
//
ID   3.2.1.65
DE   Levanase.
CA   Random hydrolysis of (2->6)-beta-D-fructofuranosidic linkages in (2->6)-
CA   beta-D-fructans (levans) containing more than 3 fructose units.
PR   PROSITE; PDOC00532;
DR   O31411, SACC_BACL7 ;
//
ID   3.2.1.66
DE   Quercitrinase.
CA   Quercitrin + H(2)O = L-rhamnose + quercetin.
CC   -!- Quercitrin is quercetin 3-L-rhamnoside.
//
ID   3.2.1.67
DE   Galacturan 1,4-alpha-galacturonidase.
AN   Exopolygalacturonase.
AN   Poly(galacturonate) hydrolase.
CA   ((1->4)-alpha-D-galacturonide)(n) + H(2)O = ((1->4)-alpha-D-
CA   galacturonide)(n-1) + D-galacturonate.
PR   PROSITE; PDOC00415;
DR   P49062, PGLR1_ARATH;  P26216, PGLR1_MAIZE;  P49063, PGLR2_ARATH;
DR   P35338, PGLR2_MAIZE;  Q6H9K0, PGLR2_PLAAC;  P35339, PGLR3_MAIZE;
DR   B0YDE8, PGLRX_ASPFC;  B8NG16, PGLRX_ASPFN;  Q4WCZ8, PGLRX_ASPFU;
DR   A2R060, PGLRX_ASPNC;  Q27UB3, PGLRX_ASPNG;  Q0CGP0, PGLRX_ASPTN;
DR   Q00293, PGLRX_ASPTU;  Q00359, PGLRX_COCCA;  A1DLC1, PGLRX_NEOFI;
DR   P24548, PGLR_OENOR ;  Q5ASG9, PGLX1_EMENI;  Q5ARN5, PGLX2_EMENI;
DR   A2QW66, PGXA_ASPNC ;  Q27UB2, PGXA_ASPNG ;  B0YAA4, PGXB_ASPFC ;
DR   B8NX60, PGXB_ASPFN ;  Q4WBK6, PGXB_ASPFU ;  A2QHG0, PGXB_ASPNC ;
DR   Q27UB1, PGXB_ASPNG ;  Q2TW03, PGXB_ASPOR ;  Q0C7H7, PGXB_ASPTN ;
DR   Q873X6, PGXB_EMENI ;  A1DAX2, PGXB_NEOFI ;  B0XYC4, PGXC_ASPFC ;
DR   B8MZZ6, PGXC_ASPFN ;  Q4WX94, PGXC_ASPFU ;  A2QEW2, PGXC_ASPNC ;
DR   Q27UB0, PGXC_ASPNG ;  Q2UQ40, PGXC_ASPOR ;  Q0CXI3, PGXC_ASPTN ;
DR   A1D7I1, PGXC_NEOFI ;  B8NJB0, RGXA_ASPFN ;  A2QBB4, RGXA_ASPNC ;
DR   Q2EQQ2, RGXA_ASPNG ;  Q2UP32, RGXA_ASPOR ;  A2QG68, RGXB_ASPNC ;
DR   A2RAY7, RGXC_ASPNC ;  A1D415, RGXC_NEOFI ;
//
ID   3.2.1.68
DE   Isoamylase.
AN   Debranching enzyme.
CA   Hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen,
CA   amylopectin and their beta-limit dextrins.
CC   -!- Also readily hydrolyzes amylopectin.
CC   -!- Differs from EC 3.2.1.41 and EC 3.2.1.142 by its inability to
CC       hydrolyze pullulan, and by limited action on alpha-limit dextrins.
CC   -!- Maltose is the smallest sugar it can release from an alpha-(1->6)-
CC       linkage.
DR   O04196, ISOA1_ARATH;  Q9M0S5, ISOA3_ARATH;  O32611, ISOA_FLASP ;
DR   P10342, ISOA_PSEAY ;  P26501, ISOA_PSEUM ;
//
ID   3.2.1.69
DE   Transferred entry: 3.2.1.41.
//
ID   3.2.1.70
DE   Glucan 1,6-alpha-glucosidase.
AN   Exo-1,6-alpha-glucosidase.
AN   Glucodextranase.
CA   Hydrolysis of (1->6)-alpha-D-glucosidic linkages in (1->6)-alpha-D-
CA   glucans and derived oligosaccharides.
CC   -!- Hydrolysis is accompanied by inversion at C-1, so that new reducing
CC       ends are released in the beta-configuration.
CC   -!- Dextrans and isomaltosaccharides are hydrolyzed, as is isomaltose,
CC       but very slowly.
CC   -!- The enzyme from some sources also possesses the activity of
CC       EC 3.2.1.59.
DR   Q59905, DEXB_STREQ ;  Q99040, DEXB_STRMU ;  Q54796, DEXB_STRPN ;
//
ID   3.2.1.71
DE   Glucan endo-1,2-beta-glucosidase.
AN   Endo-1,2-beta-glucanase.
CA   Random hydrolysis of (1->2)-glucosidic linkages in (1->2)-beta-D-glucans.
//
ID   3.2.1.72
DE   Xylan 1,3-beta-xylosidase.
AN   Exo-1,3-beta-xylosidase.
CA   Hydrolysis of successive xylose residues from the non-reducing termini of
CA   (1->3)-beta-D-xylans.
//
ID   3.2.1.73
DE   Licheninase.
AN   1,3-1,4-beta-D-glucan 4-glucanohydrolase.
AN   Beta-glucanase.
AN   Endo-beta-1,3-1,4 glucanase.
AN   Lichenase.
AN   Mixed linkage beta-glucanase.
CA   Hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans
CA   containing (1->3)- and (1->4)-bonds.
CC   -!- Acts on lichenin and cereal beta-D-glucans, but not on beta-D-glucans
CC       containing only 1,3- or 1,4-bonds.
PR   PROSITE; PDOC00507;
PR   PROSITE; PDOC00640;
PR   PROSITE; PDOC00794;
DR   P12257, GUB2_HORVU ;  P07980, GUB_BACAM  ;  P19254, GUB_BACCI  ;
DR   P27051, GUB_BACLI  ;  P04957, GUB_BACSU  ;  P37073, GUB_BREBE  ;
DR   A3DBX3, GUB_CLOTH  ;  Q84C00, GUB_CLOTM  ;  P17989, GUB_FIBSS  ;
DR   P07979, GUB_NICPL  ;  O14412, GUB_ORPSP  ;  P23904, GUB_PAEMA  ;
DR   P45797, GUB_PAEPO  ;  P45798, GUB_RHOMR  ;  Q53317, XYND_RUMFL ;
//
ID   3.2.1.74
DE   Glucan 1,4-beta-glucosidase.
AN   1,4-beta-D-glucan glucohydrolase.
AN   Exo-1,4-beta-D-glucosidase.
AN   Exo-1,4-beta-glucanase.
AN   Exo-1,4-beta-glucosidase.
CA   Hydrolysis of (1->4)-linkages in (1->4)-beta-D-glucans, to remove
CA   successive glucose units.
CC   -!- Acts on 1,4-beta-D-glucans and related oligosaccharides.
CC   -!- Cellobiose is hydrolyzed, but very slowly.
//
ID   3.2.1.75
DE   Glucan endo-1,6-beta-glucosidase.
AN   Beta-1,6-glucanase.
AN   Endo-1,6-beta-D-glucanase.
AN   Endo-1,6-beta-glucanase.
CA   Random hydrolysis of (1->6)-linkages in (1->6)-beta-D-glucans.
CC   -!- Acts on lutean, pustulan and 1,6-oligo-beta-D-glucosides.
DR   B0XRX9, EXGB_ASPFC ;  B8NBJ4, EXGB_ASPFN ;  Q4X1N4, EXGB_ASPFU ;
DR   Q2TZQ9, EXGB_ASPOR ;  Q0C8Z0, EXGB_ASPTN ;  Q5B6Q3, EXGB_EMENI ;
DR   A1DGM6, EXGB_NEOFI ;  Q8J0I9, GUN16_TRIHA;  Q7M4T0, NEG1_NEUCR ;
//
ID   3.2.1.76
DE   L-iduronidase.
CA   Hydrolysis of unsulfated alpha-L-iduronosidic linkages in dermatan
CA   sulfate.
PR   PROSITE; PDOC00787;
DR   Q01634, IDUA_CANFA ;  P35475, IDUA_HUMAN ;  P48441, IDUA_MOUSE ;
//
ID   3.2.1.77
DE   Mannan 1,2-(1,3)-alpha-mannosidase.
AN   Exo-1,2-1,3-alpha-mannosidase.
CA   Hydrolysis of (1->2)- and (1->3)-linkages in yeast mannan, releasing
CA   mannose.
CC   -!- A 1,6-alpha-D-mannan backbone remains after action on Saccharomyces
CC       cerevisiae mannan.
CC   -!- This is further attacked, but slowly.
//
ID   3.2.1.78
DE   Mannan endo-1,4-beta-mannosidase.
AN   Beta-mannanase.
AN   Endo-1,4-mannanase.
CA   Random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans,
CA   galactomannans and glucomannans.
PR   PROSITE; PDOC00565;
PR   PROSITE; PDOC51175;
DR   Q9FZ29, MAN1_ARATH ;  Q0JKM9, MAN1_ORYSJ ;  O48540, MAN1_SOLLC ;
DR   Q7Y223, MAN2_ARATH ;  Q0JJD4, MAN2_ORYSJ ;  Q9FZ03, MAN2_SOLLC ;
DR   Q9SG94, MAN3_ARATH ;  Q0DM48, MAN3_ORYSJ ;  Q9FUQ6, MAN3_SOLLC ;
DR   Q9SG95, MAN4_ARATH ;  Q10B67, MAN4_ORYSJ ;  Q8L5J1, MAN4_SOLLC ;
DR   Q9M0H6, MAN5_ARATH ;  Q5W6G0, MAN5_ORYSJ ;  Q6YM50, MAN5_SOLLC ;
DR   Q9LZV3, MAN6_ARATH ;  Q0DCM5, MAN6_ORYSJ ;  Q9FJZ3, MAN7_ARATH ;
DR   Q2RBB1, MAN7_ORYSJ ;  Q0IQJ7, MAN8_ORYSJ ;  Q6Z310, MAN9_ORYSJ ;
DR   Q0CCD0, MANA1_ASPTN;  Q0CUG5, MANA2_ASPTN;  Q00012, MANA_ASPAC ;
DR   A1CGC6, MANA_ASPCL ;  B8NVK8, MANA_ASPFN ;  A2QKT4, MANA_ASPNC ;
DR   Q2TXJ2, MANA_ASPOR ;  P49424, MANA_CELJU ;  Q5B7X2, MANA_EMENI ;
DR   Q8WPJ2, MANA_MYTED ;  A1D8Y6, MANA_NEOFI ;  P55296, MANA_PIRSP ;
DR   P49425, MANA_RHOM4 ;  P51529, MANA_STRLI ;  O05512, MANB1_BACSU;
DR   P55278, MANB2_BACSU;  P16699, MANB_BACSM ;  P22533, MANB_CALSA ;
DR   Q5B833, MANB_EMENI ;  P55297, MANB_PIRSP ;  Q0C8J3, MANC_ASPTN ;
DR   Q5AZ53, MANC_EMENI ;  P55298, MANC_PIRSP ;  Q5AVP1, MAND_EMENI ;
DR   Q5AWB7, MANE_EMENI ;  A1C8U0, MANF_ASPCL ;  B0Y9E7, MANF_ASPFC ;
DR   B8NIV9, MANF_ASPFN ;  Q4WBS1, MANF_ASPFU ;  Q2U2I3, MANF_ASPOR ;
DR   Q5AR04, MANF_EMENI ;  A1DBV1, MANF_NEOFI ;  Q9LW44, MANP_ARATH ;
//
ID   3.2.1.79
DE   Transferred entry: 3.2.1.55.
//
ID   3.2.1.80
DE   Fructan beta-fructosidase.
AN   Exo-beta-D-fructosidase.
AN   Fructanase.
CA   Hydrolysis of terminal, non-reducing (2->1)- and (2->6)-linked beta-D-
CA   fructofuranose residues in fructans.
CC   -!- Hydrolyzes inulin and levan, and also sucrose.
DR   Q03174, FRUA_STRMU ;  Q67XZ3, INV3_ARATH ;  Q8W4S6, INV6_ARATH ;
DR   P05656, SACC_BACSU ;
//
ID   3.2.1.81
DE   Beta-agarase.
AN   Agarase.
AN   Endo-beta-agarase.
CA   Hydrolysis of (1->4)-beta-D-galactosidic linkages in agarose, giving the
CA   tetramer as the predominant product.
CC   -!- Also acts on porphyran, but more slowly.
CC   -!- Cleaves the beta-(1->4) linkages of agarose in a random manner with
CC       retention of the anomeric-bond configuration, producing beta-anomers
CC       that give rise progressively to alpha-anomers when mutarotation takes
CC       place.
CC   -!- The end products of hydrolysis are neoagarotetraose and
CC       neoagarohexaose in the case of AgaA from the marine bacterium
CC       Zobellia galactanivorans, and neoagarotetraose and neoagarobiose in
CC       the case of AgaB.
DR   P85974, AGA34_AGAAL;  P48839, AGAA_VIBS7 ;  P48840, AGAB_VIBS7 ;
DR   P13734, AGAR_ALTAT ;  P07883, AGAR_STRCO ;  A8W969, AGB34_AGAAL;
//
ID   3.2.1.82
DE   Exo-poly-alpha-galacturonosidase.
AN   Exopolygalacturanosidase.
CA   Hydrolysis of pectic acid from the non-reducing end, releasing
CA   digalacturonate.
PR   PROSITE; PDOC00415;
DR   P15922, PEHX_ERWCH ;
//
ID   3.2.1.83
DE   Kappa-carrageenase.
AN   Kappa-carrageenan 4-beta-D-glycanohydrolase.
CA   Endohydrolysis of (1->4)-beta-D-linkages between D-galactose 4-sulfate
CA   and 3,6-anhydro-D-galactose in kappa-carrageenans.
CC   -!- The main products of hydrolysis are neocarrabiose-sulfate and
CC       neocarratetraose-sulfate.
CC   -!- Unlike EC 3.2.1.157, but similar to EC 3.2.1.81, this enzyme proceeds
CC       with retention of the anomeric configuration.
PR   PROSITE; PDOC00794;
DR   P43478, CGKA_ALTCA ;
//
ID   3.2.1.84
DE   Glucan 1,3-alpha-glucosidase.
AN   Exo-1,3-alpha-glucanase.
CA   Hydrolysis of terminal (1->3)-alpha-D-glucosidic links in (1->3)-alpha-D-
CA   glucans.
CC   -!- Does not act on nigeran.
DR   Q94502, GANAB_DICDI;  Q14697, GANAB_HUMAN;  Q4R4N7, GANAB_MACFA;
DR   Q8BHN3, GANAB_MOUSE;  P79403, GANAB_PIG  ;  Q9US55, GLU2A_SCHPO;
DR   P38138, GLU2A_YEAST;
//
ID   3.2.1.85
DE   6-phospho-beta-galactosidase.
AN   6-Phospho-beta-D-galactosidase.
AN   Beta-D-phosphogalactoside galactohydrolase.
CA   A 6-phospho-beta-D-galactoside + H(2)O = 6-phospho-D-galactose +
CA   an alcohol.
PR   PROSITE; PDOC00495;
DR   Q97SA9, LACG1_STRPN;  Q8DQZ1, LACG1_STRR6;  Q97QL9, LACG2_STRPN;
DR   Q8DPP6, LACG2_STRR6;  Q97EZ2, LACG_CLOAB ;  P50977, LACG_LACAC ;
DR   P14696, LACG_LACCA ;  B3W7I3, LACG_LACCB ;  P11546, LACG_LACLA ;
DR   Q29ZJ1, LACG_LACRH ;  C7N8L9, LACG_LEPBD ;  A7X569, LACG_STAA1 ;
DR   A6U3R9, LACG_STAA2 ;  Q2FEU3, LACG_STAA3 ;  Q2G2D5, LACG_STAA8 ;
DR   A5IUX8, LACG_STAA9 ;  Q2YYJ9, LACG_STAAB ;  Q5HE16, LACG_STAAC ;
DR   A6QJ33, LACG_STAAE ;  P67767, LACG_STAAM ;  P67768, LACG_STAAN ;
DR   Q6GEP0, LACG_STAAR ;  Q6G7C5, LACG_STAAS ;  A8YYF6, LACG_STAAT ;
DR   P11175, LACG_STAAU ;  P67769, LACG_STAAW ;  Q5HM41, LACG_STAEQ ;
DR   Q8CNF8, LACG_STAES ;  Q4L868, LACG_STAHJ ;  Q8E4S2, LACG_STRA3 ;
DR   B4U1G6, LACG_STREM ;  Q9EV38, LACG_STRGC ;  P50978, LACG_STRMU ;
DR   Q99Y18, LACG_STRP1 ;  P0DB40, LACG_STRP3 ;  Q5X9Y7, LACG_STRP6 ;
DR   Q8NZE1, LACG_STRP8 ;  Q1J9V2, LACG_STRPB ;  Q1JK01, LACG_STRPC ;
DR   Q1JEZ3, LACG_STRPD ;  Q1J4Q7, LACG_STRPF ;  A2RGE8, LACG_STRPG ;
DR   B8ZQ59, LACG_STRPJ ;  Q48RC8, LACG_STRPM ;  P0DB41, LACG_STRPQ ;
DR   C0MDS5, LACG_STRS7 ;  A3CPH0, LACG_STRSV ;  B9DU98, LACG_STRU0 ;
DR   C1CEE7, LACG_STRZJ ;
//
ID   3.2.1.86
DE   6-phospho-beta-glucosidase.
AN   Phospho-beta-glucosidase.
AN   Phosphocellobiase.
CA   6-phospho-beta-D-glucosyl-(1,4)-D-glucose + H(2)O = D-glucose + D-glucose
CA   6-phosphate.
CC   -!- Also hydrolyzes several other phospho-beta-D-glucosides, but not
CC       their non-phosphorylated forms.
PR   PROSITE; PDOC00495;
PR   PROSITE; PDOC01027;
DR   Q46130, ABGA_CLOLO ;  P26206, ARBB_ERWCH ;  P24240, ASCB_ECOLI ;
DR   P42973, BGLA_BACSU ;  Q46829, BGLA_ECOLI ;  P11988, BGLB_ECOLI ;
DR   P42403, BGLC_BACSU ;  P40740, BGLH_BACSU ;  Q9X108, BGLT_THEMA ;
DR   P17411, CHBF_ECOLI ;  O05508, GMUD_BACSU ;  P46320, LICH_BACSU ;
//
ID   3.2.1.87
DE   Capsular-polysaccharide endo-1,3-alpha-galactosidase.
AN   Polysaccharide depolymerase.
CA   Random hydrolysis of (1->3)-alpha-D-galactosidic linkages in Aerobacter
CA   aerogenes capsular polysaccharide.
CC   -!- Hydrolyzes the galactosyl-alpha-1,3-D-galactose linkages only in the
CC       complex substrate, bringing about depolymerization.
//
ID   3.2.1.88
DE   Beta-L-arabinosidase.
AN   Vicianosidase.
CA   A beta-L-arabinoside + H(2)O = L-arabinose + an alcohol.
//
ID   3.2.1.89
DE   Arabinogalactan endo-1,4-beta-galactosidase.
AN   Arabinogalactanase.
AN   Endo-1,4-beta-galactanase.
AN   Galactanase.
CA   Endohydrolysis of (1->4)-beta-D-galactosidic linkages in
CA   arabinogalactans.
DR   P48842, GANA_ASPAC ;  B0XPR3, GANA_ASPFC ;  B8NNI2, GANA_ASPFN ;
DR   Q4WJ80, GANA_ASPFU ;  A2RB93, GANA_ASPNC ;  Q8X168, GANA_ASPNG ;
DR   Q2UN61, GANA_ASPOR ;  Q0CTQ7, GANA_ASPTN ;  Q9Y7F8, GANA_ASPTU ;
DR   Q65CX5, GANA_BACLD ;  O07013, GANA_BACSU ;  P48841, GANA_CELJU ;
DR   Q5B153, GANA_EMENI ;  P83691, GANA_HUMIN ;  A1D3T4, GANA_NEOFI ;
DR   P83692, GANA_THIHE ;
//
ID   3.2.1.90
DE   Deleted entry.
//
ID   3.2.1.91
DE   Cellulose 1,4-beta-cellobiosidase.
AN   1,4-beta-cellobiohydrolase.
AN   1,4-beta-D-glucan cellobiohydrolase.
AN   Avicelase.
AN   Exo-1,4-beta-D-glucanase.
AN   Exocellobiohydrolase.
AN   Exoglucanase.
CA   Hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose and
CA   cellotetraose, releasing cellobiose from the non-reducing ends of the
CA   chains.
PR   PROSITE; PDOC00510;
PR   PROSITE; PDOC00563;
PR   PROSITE; PDOC00565;
DR   A1CE97, CBHA_ASPCL ;  B0Y793, CBHA_ASPFC ;  B8N7G5, CBHA_ASPFN ;
DR   Q4WNA2, CBHA_ASPFU ;  A2QPG2, CBHA_ASPNC ;  Q9UVS9, CBHA_ASPNG ;
DR   Q2UBM3, CBHA_ASPOR ;  Q0CRF7, CBHA_ASPTN ;  Q5B2Q4, CBHA_EMENI ;
DR   A1DMA5, CBHA_NEOFI ;  O59843, CBHB_ASPAC ;  A1CU44, CBHB_ASPCL ;
DR   B0Y8K2, CBHB_ASPFC ;  Q4WM08, CBHB_ASPFU ;  A2QAI7, CBHB_ASPNC ;
DR   Q9UVS8, CBHB_ASPNG ;  Q0CMT2, CBHB_ASPTN ;  Q8NK02, CBHB_EMENI ;
DR   A1DNL0, CBHB_NEOFI ;  A1CCN4, CBHC_ASPCL ;  B0XWL3, CBHC_ASPFC ;
DR   Q4WFK4, CBHC_ASPFU ;  A2QYR9, CBHC_ASPNC ;  Q0CFP1, CBHC_ASPTN ;
DR   Q5B2E8, CBHC_EMENI ;  A1DJQ7, CBHC_NEOFI ;  A3DCH1, CELK_CLOTH ;
DR   P0C2S1, CELK_CLOTM ;  P10474, GUNB_CALSA ;  Q7SA23, GUX1A_NEUCR;
DR   P38676, GUX1B_NEUCR;  Q00328, GUX1_COCCA ;  Q00548, GUX1_CRYPA ;
DR   P15828, GUX1_HUMGT ;  Q06886, GUX1_PENJA ;  P13860, GUX1_PHACH ;
DR   Q9P8P3, GUX1_TRIHA ;  P62695, GUX1_TRIKO ;  P62694, GUX1_TRIRE ;
DR   P19355, GUX1_TRIVI ;  Q92400, GUX2_AGABI ;  P50900, GUX2_CLOSR ;
DR   P07987, GUX2_TRIRE ;  P49075, GUX3_AGABI ;  Q9C1S9, GUX6_HUMIN ;
DR   P50401, GUXA_CELFA ;  P50899, GUXB_CELFA ;  P46238, GUXC_FUSOX ;
DR   P07986, GUX_CELFI  ;  P38535, XYNX_CLOTM ;
//
ID   3.2.1.92
DE   Peptidoglycan beta-N-acetylmuramidase.
AN   Exo-beta-N-acetylmuramidase.
CA   Hydrolysis of terminal, non-reducing N-acetylmuramic residues.
//
ID   3.2.1.93
DE   Alpha,alpha-phosphotrehalase.
AN   Trehalose-6-phosphate hydrolase.
CA   Alpha,alpha-trehalose 6-phosphate + H(2)O = D-glucose + D-glucose
CA   6-phosphate.
DR   P39795, TREC_BACSU ;  P28904, TREC_ECOLI ;
//
ID   3.2.1.94
DE   Glucan 1,6-alpha-isomaltosidase.
AN   Exo-isomaltohydrolase.
AN   Isomalto-dextranase.
CA   Hydrolysis of (1->6)-alpha-D-glucosidic linkages in polysaccharides,
CA   to remove successive isomaltose units from the non-reducing ends of the
CA   chains.
CC   -!- Optimum activity is on those 1,6-alpha-D-glucans containing 6, 7 and
CC       8 glucose units; those containing 3, 4 and 5 glucose units are
CC       hydrolyzed at slower rates.
DR   Q44052, IMD_ARTGO  ;
//
ID   3.2.1.95
DE   Dextran 1,6-alpha-isomaltotriosidase.
AN   Exo-isomaltotriohydrolase.
CA   Hydrolysis of (1->6)-alpha-D-glucosidic linkages in dextrans, to remove
CA   successive isomaltotriose units from the non-reducing ends of the chains.
//
ID   3.2.1.96
DE   Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase.
AN   Di-N-acetylchitobiosyl beta-N-acetylglucosaminidase.
AN   Endo-beta-N-acetylglucosaminidase.
CA   Endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose
CA   glycopeptides and glycoproteins containing the -(Man(GlcNAc)(2))Asn-
CA   structure. One N-acetyl-D-glucosamine residue remains attached to the
CA   protein; the rest of the oligosaccharide is released intact.
PR   PROSITE; PDOC00839;
DR   A7X0T9, ATL_STAA1  ;  Q2FZK7, ATL_STAA8  ;  Q5HH31, ATL_STAAC  ;
DR   Q931U5, ATL_STAAM  ;  Q99V41, ATL_STAAN  ;  Q6GI31, ATL_STAAR  ;
DR   Q6GAG0, ATL_STAAS  ;  P0C5Z8, ATL_STAAU  ;  Q8NX96, ATL_STAAW  ;
DR   O33635, ATL_STAEP  ;  Q5HQB9, ATL_STAEQ  ;  Q8CPQ1, ATL_STAES  ;
DR   P36911, EBA1_FLAME ;  P36912, EBA2_FLAME ;  P36913, EBA3_FLAME ;
DR   P80036, EBAG_FLAST ;  P04067, EBAG_STRPL ;  P0C7A1, ENASE_CHICK;
DR   A1L251, ENASE_DANRE;  Q8NFI3, ENASE_HUMAN;  Q8BX80, ENASE_MOUSE;
DR   P59205, LYTB_STRPN ;  P59206, LYTB_STRR6 ;  P39848, LYTD_BACSU ;
//
ID   3.2.1.97
DE   Glycopeptide alpha-N-acetylgalactosaminidase.
AN   D-galactosyl-3-(N-acetyl-alpha-D-galactosaminyl)-L-serine
AN   mucinaminohydrolase.
AN   Endo-alpha-acetylgalactosaminidase.
AN   Endo-alpha-GalNAc-ase.
AN   Endo-alpha-N-acetyl-D-galactosaminidase.
AN   Endo-alpha-N-acetylgalactosaminidase.
AN   Mucinaminylserine mucinaminidase.
CA   Hydrolysis of O-glycosidic linkages of sugar chains between alpha-N-
CA   acetyl-D-galactosamine and serine or threonine residues in glycoproteins.
CC   -!- The inability of the enzyme to hydrolyze substrates such as
CC       NeuAc->Gal->GalNAc-Ser/Thr, GalNAc->Gal->GalNAc->Ser/Thr,
CC       GalNAc->(Fuc)->GalNAc-Ser/Thr and NeuAc->GalNAc-Ser/Thr, together
CC       with the fact that galactose is an inhibitor of the enzyme, suggests
CC       that a non-reducing galactose terminus is necessary for recognition
CC       of the substrate by the enzyme.
CC   -!- The enzyme cannot release Gal->GalNAc from asialo (GM1) ganglioside,
CC       which suggests that the beta-N-acetylgalactosaminyl linkage is not
CC       recognized by the enzyme.
CC   -!- Formerly EC 3.2.1.110.
DR   A9WNA0, GH101_RENSM;  Q2MGH6, GH101_STRPN;  Q8DR60, GH101_STRR6;
//
ID   3.2.1.98
DE   Glucan 1,4-alpha-maltohexaosidase.
AN   Exo-maltohexaohydrolase.
AN   G6-amylase.
AN   Maltohexaose-producing amylase.
CA   Hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous
CA   polysaccharides, to remove successive maltohexaose residues from the non-
CA   reducing chain ends.
CC   -!- Cf. EC 3.2.1.3, which removes successive glucose residues.
CC   -!- Cf. EC 3.2.1.2, which removes successive maltose residues.
CC   -!- Cf. EC 3.2.1.116, which removes successive maltotriose residues.
CC   -!- Cf. EC 3.2.1.60, which removes successive maltotetraose residues.
CC   -!- The products have the alpha-configuration.
DR   P19571, AMT6_BACS7 ;
//
ID   3.2.1.99
DE   Arabinan endo-1,5-alpha-L-arabinosidase.
AN   Endo-1,5-alpha-L-arabinanase.
CA   Endohydrolysis of (1->5)-alpha-arabinofuranosidic linkages in (1->5)-
CA   arabinans.
CC   -!- Also acts on beet-arabinan, more slowly.
DR   Q9HFS9, ABNA_ASPAC ;  A1CLG4, ABNA_ASPCL ;  B0XZW5, ABNA_ASPFC ;
DR   B8NDL1, ABNA_ASPFN ;  Q4WYX7, ABNA_ASPFU ;  A2QT85, ABNA_ASPNC ;
DR   P42256, ABNA_ASPNG ;  Q2U8C6, ABNA_ASPOR ;  Q0CS14, ABNA_ASPTN ;
DR   P94522, ABNA_BACSU ;  Q5BA96, ABNA_EMENI ;  A1D5W1, ABNA_NEOFI ;
DR   B0XTS5, ABNB_ASPFC ;  B8N803, ABNB_ASPFN ;  Q4X0A5, ABNB_ASPFU ;
DR   Q2UI74, ABNB_ASPOR ;  Q0CY27, ABNB_ASPTN ;  Q5AZC8, ABNB_EMENI ;
DR   A1DHW8, ABNB_NEOFI ;  A1CN18, ABNC_ASPCL ;  B0YDT3, ABNC_ASPFC ;
DR   B8NMD3, ABNC_ASPFN ;  Q4W930, ABNC_ASPFU ;  A5AAG2, ABNC_ASPNC ;
DR   Q2U1X8, ABNC_ASPOR ;  Q0CRJ6, ABNC_ASPTN ;  Q5AUM3, ABNC_EMENI ;
DR   A1DKY5, ABNC_NEOFI ;  Q5B8T6, ABND_EMENI ;
//
ID   3.2.1.100
DE   Mannan 1,4-mannobiosidase.
AN   Exo-1,4-beta-mannobiohydrolase.
AN   Mannan 1,4-beta-mannobiosidase.
CA   Hydrolysis of (1->4)-beta-D-mannosidic linkages in (1->4)-beta-D-mannans,
CA   to remove successive mannobiose residues from the non-reducing chain
CA   ends.
//
ID   3.2.1.101
DE   Mannan endo-1,6-alpha-mannosidase.
AN   1,6-beta-D-mannan mannanohydrolase.
AN   Endo-1,6-beta-mannanase.
AN   Endo-alpha-1->6-D-mannanase.
AN   Exo-1,6-beta-mannanase.
CA   Random hydrolysis of (1->6)-alpha-D-mannosidic linkages in unbranched
CA   (1->6)-mannans.
DR   Q75DG6, DCW1_ASHGO ;  Q6FLP9, DCW1_CANGA ;  P36091, DCW1_YEAST ;
DR   Q05031, DFG5_YEAST ;  O74556, YCZ2_SCHPO ;  Q9P6I4, YHG6_SCHPO ;
DR   Q9P6I3, YHG7_SCHPO ;
//
ID   3.2.1.102
DE   Blood-group-substance endo-1,4-beta-galactosidase.
AN   Endo-beta-galactosidase.
CA   Endohydrolysis of (1->4)-beta-D-galactosidic linkages in blood group A
CA   and B substances.
CC   -!- Hydrolyzes the 1,4-beta-D-galactosyl linkages adjacent to a 1,3-
CC       alpha-D-galactosyl or N-acetylgalactosaminyl residues and a 1,2-
CC       alpha-D-fucosyl residue.
//
ID   3.2.1.103
DE   Keratan-sulfate endo-1,4-beta-galactosidase.
AN   Endo-beta-galactosidase.
CA   Endohydrolysis of (1->4)-beta-D-galactosidic linkages in keratan sulfate.
CC   -!- Hydrolyzes the 1,4-beta-D-galactosyl linkages adjacent to 1,3-beta-D-
CC       N-acetylglucosaminyl residues.
CC   -!- Also acts on some non-sulfated oligosaccharides, but only acts on
CC       blood group substances when the 1,2-linked fucosyl residues have been
CC       removed (cf. EC 3.2.1.102).
//
ID   3.2.1.104
DE   Steryl-beta-glucosidase.
CA   Cholesteryl-beta-D-glucoside + H(2)O = D-glucose + cholesterol.
CC   -!- Acts on glucosides of cholesterol and sitosterol, but not on some
CC       related sterols such as coprostanol.
//
ID   3.2.1.105
DE   3-alpha-(S)-strictosidine beta-glucosidase.
AN   Strictosidine beta-glucosidase.
CA   Strictosidine + H(2)O = D-glucose + strictosidine aglycone.
CC   -!- Does not act on a number of closely related glycosides.
CC   -!- Strictosidine is a precursor of indole alkaloids.
//
ID   3.2.1.106
DE   Mannosyl-oligosaccharide glucosidase.
AN   Processing A-glucosidase I.
CA   Exohydrolysis of the non-reducing terminal glucose residues in the
CA   mannosyl-oligosaccharide Glc(3)Man(9)GlcNAc(2).
CC   -!- Also acts, more slowly, on the corresponding glycolipids and
CC       glycopeptides.
CC   -!- Involved in the formation of high-mannose and complex glycoproteins.
DR   P53008, CWH41_YEAST;  Q19426, GCS1_CAEEL ;  O14255, GCS1_SCHPO ;
DR   Q13724, MOGS_HUMAN ;  Q80UM7, MOGS_MOUSE ;  O88941, MOGS_RAT   ;
//
ID   3.2.1.107
DE   Protein-glucosylgalactosylhydroxylysine glucosidase.
CA   Protein alpha-D-glucosyl-(1->2)-beta-D-galactosyl-L-hydroxylysine + H(2)O
CA   = D-glucose + protein beta-D-galactosyl-L-hydroxylysine.
CC   -!- Requires free, positively charged epsilon-amino group of
CC       hydroxylysine.
//
ID   3.2.1.108
DE   Lactase.
CA   Lactose + H(2)O = D-galactose + D-glucose.
CC   -!- The enzyme from intestinal mucosa is isolated as a complex which also
CC       catalyzes the reaction of EC 3.2.1.62 (cf. EC 3.2.1.23).
PR   PROSITE; PDOC00495;
DR   P09848, LPH_HUMAN  ;  P09849, LPH_RABIT  ;  Q02401, LPH_RAT    ;
//
ID   3.2.1.109
DE   Endogalactosaminidase.
CA   Endohydrolysis of (1->4)-alpha-D-galactosaminidic linkages in
CA   poly(D-galactosamine).
//
ID   3.2.1.110
DE   Transferred entry: 3.2.1.97.
//
ID   3.2.1.111
DE   1,3-alpha-L-fucosidase.
AN   Almond emulsin fucosidase I.
CA   Hydrolysis of (1->3)-linkages between alpha-L-fucose and
CA   N-acetylglucosamine residues in glycoproteins.
CC   -!- Not identical with EC 3.2.1.63.
//
ID   3.2.1.112
DE   2-deoxyglucosidase.
CA   A 2-deoxy-alpha-D-glucoside + H(2)O = 2-deoxy-D-glucose + an alcohol.
//
ID   3.2.1.113
DE   Mannosyl-oligosaccharide 1,2-alpha-mannosidase.
AN   Man9-mannosidase.
AN   ManI.
AN   Mannosidase 1A.
AN   Mannosidase 1B.
CA   Hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in the
CA   oligo-mannose oligosaccharide Man(9)(GlcNAc)(2).
CC   -!- Involved in the synthesis of glycoproteins.
DR   P53624, MA121_DROME;  P53625, MA122_DROME;  P33908, MA1A1_HUMAN;
DR   P45700, MA1A1_MOUSE;  O02773, MA1A1_PIG  ;  P45701, MA1A1_RABIT;
DR   O60476, MA1A2_HUMAN;  P39098, MA1A2_MOUSE;  Q9UKM7, MA1B1_HUMAN;
DR   A2AJ15, MA1B1_MOUSE;  B2GUY0, MA1B1_RAT  ;  Q9NR34, MA1C1_HUMAN;
DR   Q18788, MAN12_CAEEL;  P31723, MAN12_PENCI;  A1CP08, MNS1B_ASPCL;
DR   B0XMT4, MNS1B_ASPFC;  B8N417, MNS1B_ASPFN;  Q4WRZ5, MNS1B_ASPFU;
DR   A2QAS2, MNS1B_ASPNC;  Q2ULB2, MNS1B_ASPOR;  Q12563, MNS1B_ASPSA;
DR   Q0D076, MNS1B_ASPTN;  Q5BF93, MNS1B_EMENI;  A1D1W1, MNS1B_NEOFI;
DR   Q9C512, MNS1_ARATH ;  Q8J0Q0, MNS1_CANAL ;  Q9P7C3, MNS1_SCHPO ;
DR   P32906, MNS1_YEAST ;  Q8H116, MNS2_ARATH ;  Q93Y37, MNS3_ARATH ;
//
ID   3.2.1.114
DE   Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase.
AN   ManII.
AN   Mannosidase II.
CA   Hydrolysis of the terminal (1->3)- and (1->6)-linked alpha-D-mannose
CA   residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3).
CC   -!- Involved in the synthesis of glycoproteins.
DR   Q16706, MA2A1_HUMAN;  P27046, MA2A1_MOUSE;  P28494, MA2A1_RAT  ;
DR   P49641, MA2A2_HUMAN;  Q8BRK9, MA2A2_MOUSE;  Q24451, MAN2_DROME ;
//
ID   3.2.1.115
DE   Branched-dextran exo-1,2-alpha-glucosidase.
AN   Dextran alpha-1,2 debranching enzyme.
CA   Hydrolysis of (1->2)-alpha-D-glucosidic linkages at the branch points of
CA   dextrans and related polysaccharides, producing free D-glucose.
CC   -!- Does not hydrolyze disaccharides or oligosaccharides containing
CC       linear 1,2-alpha-glucosidic linkages.
//
ID   3.2.1.116
DE   Glucan 1,4-alpha-maltotriohydrolase.
AN   Exo-maltotriohydrolase.
CA   Hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous
CA   polysaccharides, to remove successive maltotriose residues from the non-
CA   reducing chain ends.
CC   -!- Cf. EC 3.2.1.2, EC 3.2.1.60, and EC 3.2.1.98.
CC   -!- The products of all these enzymes have the alpha-configuration.
//
ID   3.2.1.117
DE   Amygdalin beta-glucosidase.
CA   (R)-amygdalin + H(2)O = (R)-prunasin + D-glucose.
CC   -!- Highly specific; does not act on prunasin, linamarin, gentiobiose or
CC       cellobiose (cf. EC 3.2.1.21).
DR   P29259, AH1_PRUSE  ;  P29260, AH2_PRUSE  ;  P29261, AH3_PRUSE  ;
DR   P29262, AH4_PRUSE  ;
//
ID   3.2.1.118
DE   Prunasin beta-glucosidase.
CA   (R)-prunasin + H(2)O = D-glucose + mandelonitrile.
CC   -!- Highly specific; does not act on amygdalin, linamarin or gentiobiose
CC       (cf. EC 3.2.1.21).
DR   P29263, PH1_PRUSE  ;  P29264, PH2_PRUSE  ;  P29265, PH3_PRUSE  ;
//
ID   3.2.1.119
DE   Vicianin beta-glucosidase.
CA   (R)-vicianin + H(2)O = mandelonitrile + vicianose.
CC   -!- Also hydrolyzes, more slowly, (R)-amygdalin and (R)-prunasin, but not
CC       gentiobiose, linamarin or cellobiose.
DR   A2SY66, VICHY_VICSN;
//
ID   3.2.1.120
DE   Oligoxyloglucan beta-glycosidase.
AN   Isoprimeverose-producing oligoxyloglucan hydrolase.
CA   Hydrolysis of (1->4)-beta-D-glucosidic links in oligoxyloglucans so as to
CA   remove successive isoprimeverose (i.e. alpha-xylo-(1->6)-beta-D-
CA   glucosyl-) residues from the non-reducing chain ends.
//
ID   3.2.1.121
DE   Polymannuronate hydrolase.
CA   Endohydrolysis of the D-mannuronide linkages of polymannuronate.
CC   -!- Does not act on alginic acid, which is a copolymer of
CC       polymannuronate.
//
ID   3.2.1.122
DE   Maltose-6'-phosphate glucosidase.
AN   Phospho-alpha-glucosidase.
CA   Maltose 6'-phosphate + H(2)O = D-glucose + D-glucose 6-phosphate.
CC   -!- Hydrolyzes a variety of 6-phospho-D-glucosides, including maltose
CC       6-phosphate, alpha,alpha-trehalose 6-phosphate, sucrose 6-phosphate
CC       and p-nitrophenyl-alpha-D-glucopyranoside 6-phosphate (as a
CC       chromogenic substrate).
CC   -!- The enzyme is activated by Fe(2+), Mn(2+), Co(2+) and Ni(2+).
CC   -!- It is rapidly inactivated in air.
PR   PROSITE; PDOC01027;
DR   Q9AGA6, AGLB_KLEPN ;  P54716, GLVA_BACSU ;  Q97LM4, MALH_CLOAB ;
DR   O06901, MALH_FUSMR ;  Q03C44, PAGL1_LACC3;  Q034G9, PAGL2_LACC3;
//
ID   3.2.1.123
DE   Endoglycosylceramidase.
AN   Endo-glucosylceramidase.
AN   Endoglycoceramidase.
AN   Oligoglycosylglucosylceramide glycohydrolase.
CA   Oligoglycosylglucosyl-(1<->1)-ceramide + H(2)O = ceramide +
CA   oligoglycosylglucose.
CC   -!- An enzyme from Rhodococcus sp. which degrades various acidic and
CC       neutral glycosphingolipids to oligosaccharides and ceramides,
CC       by cleaving a glucosyl bond.
CC   -!- Does not act on monoglycosylceramides (cf. EC 3.2.1.62).
DR   Q9GV16, EGCSE_CYANO;  Q6L6S1, EGCSE_HYDVU;
//
ID   3.2.1.124
DE   3-deoxy-2-octulosonidase.
CA   Endohydrolysis of the beta-ketopyranosidic linkages of 3-deoxy-D-manno-2-
CA   octulosonate in capsular polysaccharides.
CC   -!- The enzyme from a bacteriophage catalyzes the depolymerization of
CC       capsular polysaccharides containing 3-deoxy-2-octulosonide in the
CC       cell wall of Escherichia coli.
//
ID   3.2.1.125
DE   Raucaffricine beta-glucosidase.
CA   Raucaffricine + H(2)O = D-glucose + vomilenine.
CC   -!- Highly specific; some other ajmalan glucoside alkaloids are
CC       hydrolyzed, more slowly.
//
ID   3.2.1.126
DE   Coniferin beta-glucosidase.
CA   Coniferin + H(2)O = D-glucose + coniferol.
CC   -!- Also hydrolyzes syringin, 4-cinnamyl alcohol beta-glucoside and, more
CC       slowly, some other aryl beta-glycosides.
CC   -!- A plant cell-wall enzyme involved in the biosynthesis of lignin.
//
ID   3.2.1.127
DE   1,6-alpha-L-fucosidase.
CA   Hydrolysis of (1->6)-linkages between alpha-L-fucose and N-acetyl-D-
CA   glucosamine in glycopeptides such as immunoglobulin G glycopeptide and
CA   fucosyl-asialo-agalacto-fetuin.
CC   -!- The enzyme from Aspergillus niger does not act on 1,2-, 1,3-, or 1,4-
CC       L-fucosyl linkages.
//
ID   3.2.1.128
DE   Glycyrrhizinate beta-glucuronidase.
CA   Glycyrrhizinate + H(2)O = (1->2)-beta-D-glucuronosyl-D-glucuronate +
CA   glycyrrhetinate.
CC   -!- The enzyme from Aspergillus niger is specific for the hydrolysis of
CC       the triterpenoid glycoside glycyrrhizinate from roots of Glycyrrhiza
CC       sp.
//
ID   3.2.1.129
DE   Endo-alpha-sialidase.
AN   Endo-N-acetylneuraminidase.
AN   Endoneuraminidase.
AN   Poly(alpha-2,8-sialosyl) endo-N-acetylneuraminidase.
CA   Endohydrolysis of (2->8)-alpha-sialosyl linkages in oligo- or
CA   poly(sialic) acids.
CC   -!- Although the name endo-N-acetylneuraminidase has also been used for
CC       this enzyme, this is misleading since its activity is not restricted
CC       to acetyl-substituted substrates.
CC   -!- An exo-alpha-sialidase activity is listed as EC 3.2.1.18.
CC   -!- See also 4.2.2.15.
DR   P49714, ENAN_BPK1E ;  Q04830, ENAN_BPK1F ;
//
ID   3.2.1.130
DE   Glycoprotein endo-alpha-1,2-mannosidase.
CA   Hydrolysis of the terminal alpha-D-glucosyl-(1,3)-D-mannosyl unit from
CA   the GlcMan(9)(GlcNAc)(2) oligosaccharide component of the glycoprotein
CA   produced in the Golgi membrane.
CC   -!- Involved in the synthesis of glycoproteins.
DR   Q5SRI9, MANEA_HUMAN;  Q6NXH2, MANEA_MOUSE;  Q5RD93, MANEA_PONAB;
DR   Q5GF25, MANEA_RAT  ;  Q6DE40, MANEA_XENLA;
//
ID   3.2.1.131
DE   Xylan alpha-1,2-glucuronosidase.
CA   Hydrolysis of (1->2)-alpha-D-(4-O-methyl)glucuronosyl links in the main
CA   chain of hardwood xylans.
//
ID   3.2.1.132
DE   Chitosanase.
CA   Endohydrolysis of beta-(1->4)-linkages between D-glucosamine residues in
CA   a partly acetylated chitosan.
CC   -!- A whole spectrum of chitosanases are now known that can hydrolyze
CC       various types of links in chitosan.
CC   -!- The only constant property is the endohydrolysis of GlcN-GlcN links,
CC       which is common to all known chitosanases.
CC   -!- One known chitosanase is limited to this link recognition, while the
CC       majority can also recognize GlcN-GlcNAc links or GlcNAc-GlcN links
CC       but not both.
CC   -!- They also do not recognize GlcNAc-GlcNAc links in partly acetylated
CC       chitosan.
PR   PROSITE; PDOC60000;
DR   P33673, CHIS_BACCI ;  O07921, CHIS_BACSU ;  P48846, CHIS_NOCSP ;
DR   P33665, CHIS_STRSN ;  P86799, IPLAA_MORAL;  P86800, IPLAB_MORAL;
//
ID   3.2.1.133
DE   Glucan 1,4-alpha-maltohydrolase.
AN   Maltogenic alpha-amylase.
CA   Hydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides so as
CA   to remove successive alpha-maltose residues from the non-reducing ends of
CA   the chains.
CC   -!- Acts on starch and related polysaccharides and oligosaccharides.
CC   -!- The product is alpha-maltose; cf. EC 3.2.1.2.
PR   PROSITE; PDOC51166;
DR   P32818, AMYM_BACAD ;  Q04977, AMYM_BACLI ;  P19531, AMYM_GEOSE ;
//
ID   3.2.1.134
DE   Difructose-anhydride synthase.
CA   Bis-D-fructose 2',1:2,1'-dianhydride + H(2)O = inulobiose.
CC   -!- Produces difructose anhydride by the reverse reaction of partial
CC       hydrolysis, forming an alpha-fructosidic linkage.
//
ID   3.2.1.135
DE   Neopullulanase.
CA   Hydrolysis of pullulan to panose (6-alpha-D-glucosylmaltose).
CC   -!- Cf. EC 3.2.1.41 and EC 3.2.1.57.
DR   Q60053, NEPU1_THEVU;  Q08751, NEPU2_THEVU;  P38940, NEPU_GEOSE ;
//
ID   3.2.1.136
DE   Glucuronoarabinoxylan endo-1,4-beta-xylanase.
AN   Feraxan endoxylanase.
CA   Endohydrolysis of (1->4)-beta-D-xylosyl links in some
CA   glucuronoarabinoxylans.
CC   -!- High activity toward feruloylated arabinoxylans from cereal plant
CC       cell walls.
DR   Q45070, XYNC1_BACSU;  Q6YK37, XYNC2_BACSU;
//
ID   3.2.1.137
DE   Mannan exo-1,2-1,6-alpha-mannosidase.
CA   Hydrolysis of (1->2)-alpha-D- and (1->6)-alpha-D- linkages in yeast
CA   mannan, releasing D-mannose.
CC   -!- Mannose residues linked alpha-D-1,3- are also released very slowly.
//
ID   3.2.1.138
DE   Transferred entry: 4.2.2.15.
//
ID   3.2.1.139
DE   Alpha-glucuronidase.
AN   Alpha-glucosiduronase.
CA   An alpha-D-glucuronoside + H(2)O = an alcohol + D-glucuronate.
CC   -!- Considerable differences in the specificities of the enzymes from
CC       different fungi for alpha-D-glucosiduronates have been reported.
DR   A1CC12, AGUA_ASPCL ;  B0Y2K1, AGUA_ASPFC ;  B8NGU1, AGUA_ASPFN ;
DR   Q4WW45, AGUA_ASPFU ;  A2R3X3, AGUA_ASPNC ;  Q96WX9, AGUA_ASPNG ;
DR   Q2UFP4, AGUA_ASPOR ;  Q0CJP9, AGUA_ASPTN ;  O42814, AGUA_ASPTU ;
DR   Q5AQZ4, AGUA_EMENI ;  A1DD80, AGUA_NEOFI ;  P96105, AGUA_THEMA ;
DR   Q99024, AGUA_TRIRE ;
//
ID   3.2.1.140
DE   Lacto-N-biosidase.
AN   Oligosaccharide lacto-N-biosylhydrolase.
CA   (1) Beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc +
CA   H(2)O = beta-D-Gal-(1->3)-D-GlcNAc + beta-D-Gal-(1->4)-D-Glc.
CA   (2) Lacto-N-tetraose + H(2)O = lacto-N-biose + lactose.
CC   -!- The enzyme from Streptomyces specifically hydrolyzes the terminal
CC       lacto-N-biosyl residue (beta-D-Gal-(1->3)-D-GlcNAc) from the non-
CC       reducing end of oligosaccharides with the structure beta-D-Gal-
CC       (1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->R).
CC   -!- Lacto-N-hexaose (beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-
CC       (1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc) is hydrolyzed to
CC       form first lacto-N-tetraose plus lacto-N-biose, with the subsequent
CC       formation of lactose.
CC   -!- Oligosaccharides in which the non-reducing terminal Gal or the
CC       penultimate GlcNAc are replaced by fucose or sialic acid are not
CC       substrates.
CC   -!- Asialo GM1 tetraose (beta-D-Gal-(1->3)-beta-D-GalNAc-(1->3)-beta-D-
CC       Gal-(1->4)-D-Glc) is hydrolyzed very slowly, but lacto-N-neotetraose
CC       (beta-D-Gal-(1->4)-beta-D-GalNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc) is
CC       not a substrate.
//
ID   3.2.1.141
DE   4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehalohydrolase.
AN   Malto-oligosyltrehalose trehalohydrolase.
AN   Maltooligosyl trehalose trehalohydrolase.
CA   Hydrolysis of (1->4)-alpha-D-glucosidic linkage in 4-alpha-D-((1->4)-
CA   alpha-D-glucanosyl)(n) trehalose to yield trehalose and (1->4)-alpha-D-
CA   glucan.
DR   Q9AJN6, TREZ_ARTRM ;  Q44316, TREZ_ARTSQ ;  O52520, TREZ_BREHE ;
DR   Q9RX51, TREZ_DEIRA ;  Q10769, TREZ_MYCTU ;  Q53238, TREZ_RHIS1 ;
DR   Q55088, TREZ_SULSF ;  P95867, TREZ_SULSO ;
//
ID   3.2.1.142
DE   Limit dextrinase.
AN   Amylopectin-1,6-glucosidase.
AN   R-enzyme.
CA   Hydrolysis of (1->6)-alpha-D-glucosidic linkages in alpha- and beta-limit
CA   dextrins of amylopectin and glycogen, and in amylopectin and pullulan.
CC   -!- Plant enzymes with little or no action on glycogen.
CC   -!- Action on amylopectin is incomplete, but action on alpha-limit
CC       dextrins is complete.
CC   -!- Maltose is the smallest sugar it can release from an alpha-(1->6)-
CC       linkage.
DR   Q8GTR4, PULA1_ARATH;
//
ID   3.2.1.143
DE   Poly(ADP-ribose) glycohydrolase.
CA   Hydrolyzes poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-
CA   ribose bond to produce free ADP-ribose.
CC   -!- Specific to (1''-2') linkage of ribose-ribose bond of poly(ADP-
CC       ribose).
DR   Q3SYV9, ARHL2_BOVIN;  Q5ZI51, ARHL2_CHICK;  Q66HT8, ARHL2_DANRE;
DR   Q9NX46, ARHL2_HUMAN;  Q8CG72, ARHL2_MOUSE;  Q28FQ6, ARHL2_XENTR;
DR   Q9SKB3, PARG1_ARATH;  Q8VYA1, PARG2_ARATH;  O02776, PARG_BOVIN ;
DR   O46043, PARG_DROME ;  Q86W56, PARG_HUMAN ;  O88622, PARG_MOUSE ;
DR   Q9QYM2, PARG_RAT   ;  Q867X0, PME3_CAEEL ;  Q9N5L4, PME4_CAEEL ;
//
ID   3.2.1.144
DE   3-deoxyoctulosonase.
AN   Alpha-Kdo-ase.
CA   3-deoxyoctulosonyl-lipopolysaccharide + H(2)O = 3-deoxyoctulosonic acid +
CA   lipopolysaccharide.
CC   -!- Releases Kdo (alpha- and beta-linked 3-deoxy-D-manno-octulosonic
CC       acid) from different lipopolysaccharides, including Re-LPS from
CC       Escherichia coli and Salmonella, Rd-LPS from S.minnesota, and de-O-
CC       acyl-re-LPS.
CC   -!- 4-methylumbelliferyl-alpha-Kdo (alpha-Kdo-OMec) is also a substrate.
//
ID   3.2.1.145
DE   Galactan 1,3-beta-galactosidase.
CA   Hydrolysis of terminal, non-reducing beta-D-galactose residues in (1->3)-
CA   beta-D-galactopyranans.
CC   -!- This enzyme removes not only free galactose, but also 6-glycosylated
CC       residues, e.g., (1->6)-beta-D-galactobiose, and galactose bearing
CC       oligosaccharide chains on O-6.
CC   -!- Hence, it releases branches from (arabino-galacto-(1->6))-(1->3)-
CC       beta-D-galactans.
//
ID   3.2.1.146
DE   Beta-galactofuranosidase.
AN   Beta-D-galactofuranosidase.
AN   Exo-beta-D-galactofuranosidase.
AN   Exo-beta-galactofuranosidase.
CA   Hydrolysis of terminal non-reducing beta-D-galactofuranosides, releasing
CA   galactose.
CC   -!- The enzyme from Helminthosporium sacchari detoxifies
CC       helminthosporoside, a bis(digalactosyl)terpene produced by this
CC       fungus, by releasing its four molecules of bound galactose.
//
ID   3.2.1.147
DE   Thioglucosidase.
AN   Myrosinase.
AN   Sinigrase.
AN   Sinigrinase.
CA   A thioglucoside + H(2)O = a sugar + a thiol.
CC   -!- Has a wide specificity for thioglycosides.
CC   -!- Formerly EC 3.2.3.1.
PR   PROSITE; PDOC00495;
DR   Q8GRX1, BGL34_ARATH;  Q3ECS3, BGL35_ARATH;  Q9C8K1, BGL36_ARATH;
DR   Q9C5C2, BGL37_ARATH;  P37702, BGL38_ARATH;  Q3E8E5, BGL39_ARATH;
DR   P29737, MYR1_SINAL ;  P29738, MYR2_SINAL ;  P29092, MYR3_SINAL ;
DR   P29736, MYRA_SINAL ;  Q95X01, MYRO1_BREBR;  P83179, MYRO2_BREBR;
DR   Q00326, MYRO_BRANA ;
//
ID   3.2.1.148
DE   Transferred entry: 4.4.1.21.
//
ID   3.2.1.149
DE   Beta-primeverosidase.
CA   A 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside + H(2)O = 6-O-(beta-
CA   D-xylopyranosyl)-beta-D-glucopyranose + an alcohol.
CC   -!- The enzyme is responsible for the formation of the alcoholic aroma in
CC       oolong and black tea.
CC   -!- In addition to beta-primeverosides (i.e. 6-O-(beta-D-xylopyranosyl)-
CC       beta-D-glucopyranosides), it also hydrolyzes 6-O-(beta-D-
CC       apiofuranosyl)-beta-D-glucopyranosides and, less rapidly, beta-
CC       vicianosides and 6-O-(alpha-L-arabinofuranosyl)-beta-D-
CC       glucopyranosides, but not beta-glucosides.
CC   -!- Geranyl-, linaloyl-, benzyl- and p-nitrophenol glycosides are all
CC       hydrolyzed.
//
ID   3.2.1.150
DE   Oligoxyloglucan reducing-end-specific cellobiohydrolase.
CA   Hydrolysis of cellobiose from the reducing end of xyloglucans consisting
CA   of a beta-(1->4)-linked glucan carrying alpha-D-xylosyl groups on O-6 of
CA   the glucose residues. To be a substrate, the first residue must be
CA   unsubstituted, the second residue may bear a xylosyl group, whether
CA   further glycosylated or not, and the third residue, which becomes the new
CA   terminus by the action of the enzyme, is preferably xylosylated, but this
CA   xylose residue must not be further substituted.
CC   -!- The enzyme is found in the fungus Geotrichum sp. M128.
CC   -!- The substrate is a hemicellulose found in plant cell walls.
DR   Q8J0D2, CBHRE_GEOS1;  Q5BD38, XGCA_EMENI ;  A1DAU0, XGCA_NEOFI ;
//
ID   3.2.1.151
DE   Xyloglucan-specific endo-beta-1,4-glucanase.
AN   1,4-beta-D-glucan glucanohydrolase.
AN   XEG.
AN   Xyloglucan endo-beta-1,4-glucanase.
AN   Xyloglucanase.
AN   Xyloglucanendohydrolase.
CA   Xyloglucan + H(2)O = xyloglucan oligosaccharides.
CC   -!- The enzyme from Aspergillus aculeatus is specific for xyloglucan and
CC       does not hydrolyze other cell-wall components.
CC   -!- The reaction involves endohydrolysis of 1,4-beta-D-glucosidic
CC       linkages in xyloglucan with retention of the beta-configuration of
CC       the glycosyl residues.
DR   O94218, XGEA_ASPAC ;  A1CRJ0, XGEA_ASPCL ;  B0XNQ1, XGEA_ASPFC ;
DR   B8N3L3, XGEA_ASPFN ;  Q4WJU8, XGEA_ASPFU ;  A2Q877, XGEA_ASPNC ;
DR   A1XP58, XGEA_ASPNG ;  Q2UK93, XGEA_ASPOR ;  Q0CRC9, XGEA_ASPTN ;
DR   Q5BG78, XGEA_EMENI ;  A1D4F1, XGEA_NEOFI ;
//
ID   3.2.1.152
DE   Mannosylglycoprotein endo-beta-mannosidase.
AN   Endo-beta-mannosidase.
CA   Hydrolysis of the alpha-D-mannosyl-(1->6)-beta-D-mannosyl-(1->4)-beta-D-
CA   N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequence of
CA   glycoprotein to alpha-D-mannosyl-(1->6)-D-mannose and beta-D-
CA   N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequences.
CC   -!- The substrate group is a substituent on N-4 of an asparagine residue
CC       in the glycoprotein.
CC   -!- The mannose residue at the non-reducing end of the sequence may carry
CC       further alpha-D-mannosyl groups on O-3 or O-6, but such a substituent
CC       on O-3 of the beta-D-mannosyl group prevents the action of the
CC       enzyme.
CC   -!- The enzyme was obtained from the lily, Lilium longiflorum.
DR   Q75W54, EBM_ARATH  ;  Q5H7P5, EBM_LILLO  ;
//
ID   3.2.1.153
DE   Fructan beta-(2,1)-fructosidase.
AN   1-FEH II.
AN   1-FEH w1.
AN   1-FEH w2.
AN   1-fructan exohydrolase.
AN   Beta-(2,1)-D-fructan fructohydrolase.
AN   Beta-(2-1)-D-fructan fructohydrolase.
AN   Beta-(2-1)-linkage-specific fructan-beta-fructosidase.
AN   Beta-(2-1)fructan exohydrolase.
AN   Inulinase.
CA   Hydrolysis of terminal, non-reducing (2->1)-linked beta-D-fructofuranose
CA   residues in fructans.
CC   -!- Possesses one of the activities of EC 3.2.1.80.
CC   -!- While the best substrates are the inulin-type fructans, such as
CC       1-kestose (beta-D-fructofuranosyl-(2->1)-beta-D-fructofuranosyl
CC       alpha-D-glucopyranoside) and 1,1-nystose (beta-D-fructofuranosyl-
CC       (2->1)-beta-D-fructofuranosyl-(2->1)-beta-D-fructofuranosyl alpha-D-
CC       glucopyranoside), some (but not all) levan-type fructans can also be
CC       hydrolyzed, but more slowly (see EC 3.2.1.154).
CC   -!- Sucrose, while being a very poor substrate, can substantially inhibit
CC       enzyme activity in some cases.
DR   Q84PN8, 1FEH1_WHEAT;  Q84LA1, 1FEH2_WHEAT;  B6DZC8, 1FEH3_WHEAT;
DR   B6DZD1, 1FEH_AEGSP ;  B6DZD2, 1FEH_AEGTA ;  D2IGW7, 1FEH_BROPI ;
DR   Q70AT7, 1FEH_HORVU ;  B6DXP5, 1FEH_LEYCH ;  B6DZD0, 1FEH_TRIUA ;
//
ID   3.2.1.154
DE   Fructan beta-(2,6)-fructosidase.
AN   6-FEH.
AN   Beta-(2-6)-fructan exohydrolase.
AN   Levanase.
CA   Hydrolysis of terminal, non-reducing (2->6)-linked beta-D-fructofuranose
CA   residues in fructans.
CC   -!- Possesses one of the activities of EC 3.2.1.80.
CC   -!- While the best substrates are the levan-type fructans such as
CC       6-kestotriose (beta-D-fructofuranosyl-(2->6)-beta-D-fructofuranosyl
CC       alpha-D-glucopyranoside) and 6,6-kestotetraose (beta-D-
CC       fructofuranosyl-(2->6)-beta-D-fructofuranosyl-(2->6)-beta-D-
CC       fructofuranosyl alpha-D-glucopyranoside), some (but not all) inulin-
CC       type fructans can also be hydrolyzed, but more slowly (cf.
CC       EC 3.2.1.153).
CC   -!- Sucrose, while being a very poor substrate, can substantially inhibit
CC       enzyme activity in some cases.
DR   Q70XE6, 6FEH_BETVU ;  Q2UXF7, 6FEH_WHEAT ;
//
ID   3.2.1.155
DE   Xyloglucan-specific exo-beta-1,4-glucanase.
CA   Xyloglucan + H(2)O = xyloglucan oligosaccharides (exohydrolysis of
CA   (1->4)-beta-D-glucosidic linkages in xyloglucan).
CC   -!- The enzyme from Chrysosporium lucknowense is an endoglucanase, i.e.
CC       acquires the specificity of EC 3.2.1.151, when it acts on linear
CC       substrates without bulky substituents on the polymeric backbone (e.g.
CC       carboxymethylcellulose); however, it switches to an exoglucanase mode
CC       of action when bulky side chains are present (as in the case of
CC       xyloglucan).
CC   -!- Can also act on barley beta-glucan, but more slowly.
CC   -!- Formerly EC 3.2.1.160.
DR   Q7Z9M8, XG74_TRIRE ;
//
ID   3.2.1.156
DE   Oligosaccharide reducing-end xylanase.
AN   Reducing end xylose-releasing exo-oligoxylanase.
AN   Rex.
CA   Hydrolysis of (1->4)-beta-D-xylose residues from the reducing end of
CA   oligosaccharides.
CC   -!- Acts rapidly on the beta-anomer of beta-D-xylopyranosyl-(1->4)-beta-
CC       D-xylopyranose, leaving the new reducing end in the a configuration.
CC   -!- Also acts on longer oligosaccharides that have this structure at
CC       their reducing ends.
CC   -!- The penultimate residue must be xylose, but replacing either of the
CC       other two residues with glucose merely slows the rate greatly.
DR   Q9KB30, REOX_BACHD ;  A1A048, REOX_BIFAA ;
//
ID   3.2.1.157
DE   Iota-carrageenase.
CA   Endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and
CA   3,6-anhydro-D-galactose-2-sulfate in iota-carrageenans.
CC   -!- The main products of hydrolysis are iota-neocarratetraose sulfate and
CC       iota-neocarrahexaose sulfate.
CC   -!- Iota-neocarraoctaose is the shortest substrate oligomer that can be
CC       cleaved.
CC   -!- Unlike EC 3.2.1.81 and EC 3.2.1.83, this enzyme proceeds with
CC       inversion of the anomeric configuration.
CC   -!- Iota-carrageenan differs from kappa-carrageenan by possessing a sulfo
CC       group on O-2 of the 3,6-anhydro-D-galactose residues, in addition to
CC       that present in the kappa-compound on O-4 of the D-galactose
CC       residues.
DR   Q9F5I8, CGIA_ALTFO ;  Q9F284, CGIA_ZOBGA ;
//
ID   3.2.1.158
DE   Alpha-agarase.
AN   Agarase A33.
CA   Endohydrolysis of 1,3-alpha-L-galactosidic linkages in agarose, yielding
CA   agarotetraose as the major product.
CF   Calcium.
CC   -!- The enzyme from Thalassomonas sp. can use agarose, agarohexaose and
CC       neoagarohexaose as substrate.
CC   -!- The products of agarohexaose hydrolysis are dimers and tetramers,
CC       with agarotetraose being the predominant product, whereas hydrolysis
CC       of neoagarohexaose gives rise to two types of trimer.
CC   -!- While the enzyme can also hydrolyze the highly sulfated agarose
CC       porphyran very efficiently, it cannot hydrolyze kappa-carrageenan and
CC       iota-carrageenan.
DR   Q9LAP7, AAGAR_ALTAG;  A1IGV8, AAGAR_THASX;
//
ID   3.2.1.159
DE   Alpha-neoagaro-oligosaccharide hydrolase.
AN   Alpha-NAOS hydrolase.
AN   Alpha-neoagarooligosaccharide hydrolase.
CA   Hydrolysis of the 1,3-alpha-L-galactosidic linkages of neoagaro-
CA   oligosaccharides that are smaller than a hexamer, yielding 3,6-anhydro-L-
CA   galactose and D-galactose.
CC   -!- When neoagarohexaose is used as a substrate, the oligosaccharide is
CC       cleaved at the non-reducing end to produce 3,6-anhydro-L-galactose
CC       and agaropentaose, which is further hydrolyzed to agarobiose and
CC       agarotriose.
CC   -!- With neoagarotetraose as substrate, the products are predominantly
CC       agarotriose and 3,6-anhydro-L-galactose.
CC   -!- In Vibrio sp. the actions of EC 3.2.1.81 and EC 3.2.1.159 can be used
CC       to degrade agarose to 3,6-anhydro-L-galactose and D-galactose.
//
ID   3.2.1.160
DE   Transferred entry: 3.2.1.155.
//
ID   3.2.1.161
DE   Beta-apiosyl-beta-glucosidase.
AN   Furcatin hydrolase.
AN   Isoflavonoid 7-O-beta-apiosyl-glucoside beta-glucosidase.
AN   Isoflavonoid-7-O-beta(D-apiosyl-(1->6)-beta-D-glucoside) disaccharidase.
CA   7-(beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy)isoflavonoid +
CA   H(2)O = a 7-hydroxyisoflavonoid + beta-D-apiofuranosyl-(1->6)-D-glucose.
CC   -!- Removes disaccharides from the natural substrates dalpatein 7-O-beta-
CC       D-apiofuranosyl-(1->6)-beta-D-glucopyranoside and 7-hydroxy-
CC       2',4',5',6-tetramethoxy-7-O-beta-D-apiofuranosyl-(1->6)-beta-D-
CC       glucopyranoside (dalnigrein 7-O-beta-D-apiofuranosyl-(1->6)-beta-D-
CC       glucopyranoside) although it can also remove a single glucose residue
CC       from isoflavonoid 7-O-glucosides.
CC   -!- Daidzin and genistin are also substrates.
PR   PROSITE; PDOC00495;
DR   A3RF67, BAGBG_DALNI;  Q75W17, FURH_VIBFR ;
//
ID   3.2.1.162
DE   Lambda-carrageenase.
AN   Endo-beta-1,4-carrageenose 2,6,2'-trisulfate-hydrolase.
CA   Endohydrolysis of (1->4)-beta-linkages in the backbone of lambda-
CA   carrageenan, resulting in the tetrasaccharide alpha-D-Galp2,6S(2)-(1->3)-
CA   beta-D-Galp2S-(1->4)-alpha-D-Galp2,6S(2)-(1->3)-D-Galp2S.
CC   -!- The enzyme from Pseudoalteromonas sp. is specific for lambda-
CC       carrageenan.
CC   -!- Iota-carrageenan (see EC 3.2.1.157), kappa-carrageenan (see
CC       EC 3.2.1.83), agarose and porphyran are not substrates.
DR   Q0JRK4, CGLA_ALTCA ;  Q05JY7, CGLA_PSEAS ;
//
ID   3.2.1.163
DE   1,6-alpha-D-mannosidase.
CA   Hydrolysis of the 1,6-linked alpha-D-mannose residues in alpha-D-Manp-
CA   (1->6)-D-Manp.
CC   -!- Specific for (1->6)-linked mannobiose and has no activity toward any
CC       other linkages, or toward p-nitrophenyl-alpha-D-mannopyranoside or
CC       mannan from Saccharomyces cerevisiae (baker's yeast).
CC   -!- It is strongly inhibited by Mn(2+) but does not require Ca(2+) or any
CC       other metal cofactor for activity.
//
ID   3.2.1.164
DE   Galactan endo-1,6-beta-galactosidase.
AN   Endo-1,6-beta-galactanase.
AN   Endo-beta-(1->6)-galactanase.
CA   Endohydrolysis of (1->6)-beta-D-galactosidic linkages in arabinogalactan
CA   proteins and (1->3):(1->6)-beta-galactans to yield galactose and beta-
CA   (1->6)-galactaobiose as the final products.
CC   -!- Specifically hydrolyzes 1,6-beta-D-galactooligosaccharides with a
CC       degree of polymerization (DP) higher than 3, and their acidic
CC       derivatives with 4-O-methylglucosyluronate or glucosyluronate groups
CC       at the non-reducing terminals.
CC   -!- 1,3-beta-D- and 1,4-beta-D-galactosyl residues cannot act as
CC       substrates.
CC   -!- Can also hydrolyze alpha-L-arabinofuranosidase-treated
CC       arabinogalactan protein (AGP) extracted from radish roots.
CC   -!- AGPs are thought to be involved in many physiological events, such as
CC       cell division, cell expansion and cell death.
DR   Q76FP5, 6GAL_TRIVI ;
//
ID   3.2.1.165
DE   Exo-1,4-beta-D-glucosaminidase.
AN   Exo-beta-D-glucosaminidase.
AN   Exochitosanase.
AN   GlcNase.
CA   Hydrolysis of chitosan or chitosan oligosaccharides to remove successive
CA   D-glucosamine residues from the non-reducing termini.
CC   -!- Chitosan is a partially or totally N-deacetylated chitin derivative
CC       that is found in the cell walls of some phytopathogenic fungi and
CC       comprises D-glucosamine residues with a variable content of GlcNAc
CC       residues.
CC   -!- Acts specifically on chitooligosaccharides and chitosan, having
CC       maximal activity on chitotetraose, chitopentaose and their
CC       corresponding alcohols.
CC   -!- Can degrade GlcN-GlcNAc but not GlcNAc-GlcNAc.
DR   Q56F26, EBDG_AMYOR ;  C0LRA7, EBDG_HYPVI ;  Q82NR8, EBDG_STRAW ;
DR   Q4R1C4, EBDG_TRIRE ;
//
ID   3.2.1.166
DE   Heparanase.
AN   Hpa1 heparanase.
AN   HPSE.
CA   Endohydrolysis of (1->4)-beta-D-glycosidic bonds of heparan sulfate
CA   chains in heparan sulfate proteoglycan.
CC   -!- Heparanase cleaves the linkage between a glucuronic acid unit and an
CC       N-sulfo glucosamine unit carrying either a 3-O-sulfo or a 6-O-sulfo
CC       group.
CC   -!- Heparanase-1 cuts macromolecular heparin into fragments of 5000-20000
CC       Da.
CC   -!- The enzyme cleaves the heparan sulfate glycosaminoglycans from
CC       proteoglycan core proteins and degrades them to small
CC       oligosaccharides.
CC   -!- Inside cells, the enzyme is important for the normal catabolism of
CC       heparan sulfate proteoglycans, generating glycosaminoglycan fragments
CC       that are then transported to lysosomes and completely degraded.
CC   -!- When secreted, heparanase degrades basement membrane heparan sulfate
CC       glycosaminoglycans at sites of injury or inflammation, allowing
CC       extravasion of immune cells into nonvascular spaces and releasing
CC       factors that regulate cell proliferation and angiogenesis.
//
ID   3.2.1.167
DE   Baicalin-beta-D-glucuronidase.
AN   Baicalinase.
CA   Baicalin + H(2)O = baicalein + D-glucuronate.
CC   -!- The enzyme also hydrolyzes wogonin 7-O-beta-D-glucuronide and
CC       oroxylin 7-O-beta-D-glucuronide with lower efficiency.
CC   -!- Neglegible activity with p-nitrophenyl-beta-D-glucuronide.
//
ID   3.2.1.168
DE   Hesperidin 6-O-alpha-L-rhamnosyl-beta-D-glucosidase.
CA   Hesperidin + H(2)O = hesperetin + rutinose.
CC   -!- The enzyme exhibits high specificity toward 7-O-linked flavonoid
CC       beta-rutinosides.
//
ID   3.2.1.169
DE   Protein O-GlcNAcase.
AN   Glycoside hydrolase O-GlcNAcase.
AN   O-GlcNAc hydrolase.
AN   O-GlcNAcase.
AN   OGA.
CA   (1) [Protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine + H(2)O = [protein]-
CA   L-serine + N-acetyl-D-glucosamine.
CA   (2) [Protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine + H(2)O =
CA   [protein]-L-threonine + N-acetyl-D-glucosamine.
CC   -!- Within higher eukaryotes post-translational modification of protein
CC       serines/threonines with N-acetylglucosamine (O-GlcNAc) is dynamic,
CC       inducible and abundant, regulating many cellular processes by
CC       interfering with protein phosphorylation.
CC   -!- EC 2.4.1.155 transfers GlcNAc onto substrate proteins and
CC       EC 3.2.1.169 cleaves GlcNAc from the modified proteins.
DR   O60502, NCOAT_HUMAN;  Q9EQQ9, NCOAT_MOUSE;  Q89ZI2, OGA_BACTN  ;
DR   Q0TR53, OGA_CLOP1  ;  Q8XL08, OGA_CLOPE  ;
//
ID   3.2.1.170
DE   Mannosylglycerate hydrolase.
AN   2-O-(6-phospho-mannosyl)-D-glycerate hydrolase.
CA   2-O-(6-phospho-alpha-D-mannosyl)-D-glycerate + H(2)O = D-mannose
CA   6-phosphate + D-glycerate.
CC   -!- The enzyme participates in the mannosylglycerate degradation pathway
CC       of some bacteria.
CC   -!- Mannosylglycerate is phosphorylated during transport into the cell,
CC       and the phosphorylated form is hydrolyzed by this enzyme.
DR   Q9KER1, MNGB_BACHD ;  P54746, MNGB_ECOLI ;
//
ID   3.2.1.n1
DE   Blood group B branched chain alpha-1,3-galactosidase.
CA   Hydrolysis of terminal, non-reducing branched (1->3)-alpha-D-galactosidic
CA   residues, producing free D-galactose.
CC   -!- The enzyme has exclusive specificity for the branched blood group B
CC       structures.
DR   B2UL12, GLAA_AKKM8 ;  Q5L7M8, GLAA_BACFN ;  Q64MU6, GLAA_BACFR ;
DR   Q8A2Z5, GLAA_BACTN ;  B1KD83, GLAA_SHEWM ;  Q826C5, GLAA_STRAW ;
DR   B1V8K7, GLAA_STRGU ;  A6KWM0, GLAB1_BACV8;  A6L2M8, GLAB2_BACV8;
DR   B2UNU8, GLAB_AKKM8 ;  Q5LGZ8, GLAB_BACFN ;  Q64XV2, GLAB_BACFR ;
DR   Q89ZX0, GLAB_BACTN ;  A6LFT2, GLAB_PARD8 ;
//
ID   3.2.1.n2
DE   Blood group B linear chain alpha-1,3-galactosidase.
CA   Hydrolysis of terminal, non-reducing linear (1->3)-alpha-D-galactosidic
CA   residues, producing free D-galactose.
DR   A6KWM0, GLAB1_BACV8;  A6L2M8, GLAB2_BACV8;  B2UNU8, GLAB_AKKM8 ;
DR   Q5LGZ8, GLAB_BACFN ;  Q64XV2, GLAB_BACFR ;  Q89ZX0, GLAB_BACTN ;
DR   A6LFT2, GLAB_PARD8 ;
//
ID   3.2.1.n3
DE   Dictyostelium lysozyme A.
CA   Hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and
CA   N-acetyl-D-glucosamine residues in a peptidoglycan.
CC   -!- Differs from EC 3.2.1.17, lysozyme, as it does not hydrolyze linkages
CC       between N-acetyl-D-glucosamine residues.
DR   Q8T1G4, LYSA_DICDI ;
//
ID   3.2.2.1
DE   Purine nucleosidase.
AN   IAG-NH.
AN   IAG-nucleoside hydrolase.
AN   Inosine-adenosine-guanosine preferring nucleoside hydrolase.
AN   N-D-ribosylpurine ribohydrolase.
AN   N-ribosyl purine ribohydrolase.
AN   Nucleosidase.
AN   Nucleosidase g.
AN   Nucleoside hydrolase.
AN   Purine beta-ribosidase.
AN   Purine nucleoside hydrolase.
AN   Purine ribonucleosidase.
AN   Purine-specific nucleoside N-ribohydrolase.
AN   Ribonucleoside hydrolase.
CA   A purine nucleoside + H(2)O = D-ribose + a purine base.
CC   -!- The enzyme from the bacterium Ochrobactrum anthropi specifically
CC       catalyzes the irreversible N-riboside hydrolysis of purine
CC       nucleosides.
CC   -!- Pyrimidine nucleosides, purine and pyrimidine nucleotides, NAD(+),
CC       NADP(+) and nicotinaminde mononucleotide are not substrates.
PR   PROSITE; PDOC00960;
//
ID   3.2.2.2
DE   Inosine nucleosidase.
AN   Inosinase.
CA   Inosine + H(2)O = D-ribose + hypoxanthine.
//
ID   3.2.2.3
DE   Uridine nucleosidase.
AN   Uridine ribohydrolase.
CA   Uridine + H(2)O = D-ribose + uracil.
DR   Q9SJM7, URH1_ARATH ;  Q6ZJ05, URH1_ORYSJ ;  Q04179, URH1_YEAST ;
DR   Q8LAC4, URH2_ARATH ;  Q652Q8, URH2_ORYSJ ;
//
ID   3.2.2.4
DE   AMP nucleosidase.
CA   AMP + H(2)O = D-ribose 5-phosphate + adenine.
DR   P0AE13, AMN_ECO57  ;  P0AE12, AMN_ECOLI  ;
//
ID   3.2.2.5
DE   NAD(+) nucleosidase.
AN   ADP-ribosyl cyclase.
AN   Diphosphopyridine nucleosidase.
AN   DPN hydrolase.
AN   DPNase.
AN   NAD glycohydrolase.
AN   NAD nucleosidase.
AN   NADase.
AN   Nicotinamide adenine dinucleotide glycohydrolase.
AN   Nicotinamide adenine dinucleotide nucleosidase.
CA   NAD(+) + H(2)O = ADP-ribose + nicotinamide.
CC   -!- This enzyme can also hydrolyze NADP(+) to yield phospho-ADP-ribose
CC       and nicotinamide, but more slowly.
DR   Q10588, BST1_HUMAN ;  Q64277, BST1_MOUSE ;  Q63072, BST1_RAT   ;
DR   P28907, CD38_HUMAN ;  Q5VAN0, CD38_MACFA ;  P56528, CD38_MOUSE ;
DR   Q9MZ03, CD38_RABIT ;  Q64244, CD38_RAT   ;  P29241, NADA_APLCA ;
DR   Q27312, NADA_APLKU ;
//
ID   3.2.2.6
DE   NAD(P)(+) nucleosidase.
CA   NAD(P)(+) + H(2)O = ADP-ribose(P) + nicotinamide.
CC   -!- Also catalyzes transfer of ADP-ribose(P) residues.
//
ID   3.2.2.7
DE   Adenosine nucleosidase.
AN   Adenosinase.
CA   Adenosine + H(2)O = D-ribose + adenine.
CC   -!- Also acts on adenosine N-oxide.
//
ID   3.2.2.8
DE   Ribosylpyrimidine nucleosidase.
AN   N-ribosylpyrimidine nucleosidase.
AN   N-ribosylpyrimidine ribohydrolase.
AN   Nucleoside ribohydrolase.
AN   Pyrimidine nucleosidase.
CA   A pyrimidine nucleoside + H(2)O = D-ribose + a pyrimidine base.
CC   -!- Also hydrolyzes purine D-ribonucleosides, more slowly.
CC   -!- 2'-, 3'- and 5'-deoxynucleosides are not substrates.
DR   A7ZNY5, RIHB_ECO24 ;  B7UFH8, RIHB_ECO27 ;  B7MF76, RIHB_ECO45 ;
DR   B7LAI5, RIHB_ECO55 ;  Q8XE94, RIHB_ECO57 ;  B5YWV3, RIHB_ECO5E ;
DR   B7NMX6, RIHB_ECO7I ;  B7MX26, RIHB_ECO81 ;  B7M510, RIHB_ECO8A ;
DR   C4ZU12, RIHB_ECOBW ;  B1X860, RIHB_ECODH ;  A8A225, RIHB_ECOHS ;
DR   A1AD20, RIHB_ECOK1 ;  Q0TFS8, RIHB_ECOL5 ;  Q8FFT8, RIHB_ECOL6 ;
DR   B1IYA8, RIHB_ECOLC ;  P33022, RIHB_ECOLI ;  B7N5C5, RIHB_ECOLU ;
DR   B6I8L3, RIHB_ECOSE ;  B1LKQ9, RIHB_ECOSM ;  Q1R9R0, RIHB_ECOUT ;
DR   B7LVC3, RIHB_ESCF3 ;  Q31YW9, RIHB_SHIBS ;  Q32ER0, RIHB_SHIDS ;
DR   Q0T2W2, RIHB_SHIF8 ;  Q83KF1, RIHB_SHIFL ;  Q3Z044, RIHB_SHISS ;
//
ID   3.2.2.9
DE   Adenosylhomocysteine nucleosidase.
AN   5'-methyladenosine nucleosidase.
AN   AdoHcy/MTA nucleosidase.
AN   S-adenosylhomocysteine hydrolase.
AN   S-adenosylhomocysteine nucleosidase.
AN   S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase.
CA   (1) S-adenosyl-L-homocysteine + H(2)O = S-(5-deoxy-D-ribos-5-yl)-L-
CA   homocysteine + adenine.
CA   (2) S-methyl-5'-thioadenosine + H(2)O = 5-methyl-5-thio-D-ribose +
CA   adenine.
DR   Q9T0I8, MTN1_ARATH ;  Q7XA67, MTN2_ARATH ;  A3N2T5, MTNN_ACTP2 ;
DR   B3H2N4, MTNN_ACTP7 ;  B0BRW3, MTNN_ACTPJ ;  A6VPH1, MTNN_ACTSZ ;
DR   A0KIZ1, MTNN_AERHH ;  A4SP53, MTNN_AERS4 ;  B6EKZ7, MTNN_ALISL ;
DR   B7GIU7, MTNN_ANOFW ;  A7Z721, MTNN_BACA2 ;  C3P964, MTNN_BACAA ;
DR   C3L5Y0, MTNN_BACAC ;  A0RIY7, MTNN_BACAH ;  Q81LL4, MTNN_BACAN ;
DR   B7JP64, MTNN_BACC0 ;  Q730G0, MTNN_BACC1 ;  B7IYM7, MTNN_BACC2 ;
DR   C1ESR9, MTNN_BACC3 ;  B7HE08, MTNN_BACC4 ;  B7HQD2, MTNN_BACC7 ;
DR   A7GT52, MTNN_BACCN ;  Q812S1, MTNN_BACCR ;  Q634H0, MTNN_BACCZ ;
DR   Q9KDD4, MTNN_BACHD ;  Q6HDF1, MTNN_BACHK ;  Q65GT9, MTNN_BACLD ;
DR   A8FFL1, MTNN_BACP2 ;  Q5WHL7, MTNN_BACSK ;  O32028, MTNN_BACSU ;
DR   A9VHZ5, MTNN_BACWK ;  Q1LTN6, MTNN_BAUCH ;  B8D909, MTNN_BUCA5 ;
DR   P57306, MTNN_BUCAI ;  O51931, MTNN_BUCAP ;  B8D7B4, MTNN_BUCAT ;
DR   Q89AQ7, MTNN_BUCBP ;  Q1QVV7, MTNN_CHRSD ;  A8ALC9, MTNN_CITK8 ;
DR   Q47UY5, MTNN_COLP3 ;  C6BU87, MTNN_DESAD ;  Q6AQW7, MTNN_DESPS ;
DR   A7ZHQ1, MTNN_ECO24 ;  B7UIK6, MTNN_ECO27 ;  B7MBE2, MTNN_ECO45 ;
DR   B7LGM1, MTNN_ECO55 ;  P0AF14, MTNN_ECO57 ;  B5Z0D9, MTNN_ECO5E ;
DR   B7NIC2, MTNN_ECO7I ;  B7MP21, MTNN_ECO81 ;  B7M1A0, MTNN_ECO8A ;
DR   C4ZRQ2, MTNN_ECOBW ;  B1XD29, MTNN_ECODH ;  A7ZWA7, MTNN_ECOHS ;
DR   A1A7K5, MTNN_ECOK1 ;  Q0TLH2, MTNN_ECOL5 ;  P0AF13, MTNN_ECOL6 ;
DR   B1IQI1, MTNN_ECOLC ;  P0AF12, MTNN_ECOLI ;  B7N828, MTNN_ECOLU ;
DR   B6HZD5, MTNN_ECOSE ;  B1LGW2, MTNN_ECOSM ;  Q1RG29, MTNN_ECOUT ;
DR   C5BAP4, MTNN_EDWI9 ;  A4W6Q6, MTNN_ENT38 ;  A7MGS5, MTNN_ENTS8 ;
DR   Q6D1Z4, MTNN_ERWCT ;  B2VE28, MTNN_ERWT9 ;  B7LWC0, MTNN_ESCF3 ;
DR   B1YJD6, MTNN_EXIS2 ;  C4L559, MTNN_EXISA ;  Q5KWV9, MTNN_GEOKA ;
DR   C5D4X9, MTNN_GEOSW ;  A4IR66, MTNN_GEOTN ;  Q7VKK0, MTNN_HAEDU ;
DR   Q4QL83, MTNN_HAEI8 ;  A5UCP4, MTNN_HAEIE ;  A5UIX8, MTNN_HAEIG ;
DR   P45113, MTNN_HAEIN ;  B8F704, MTNN_HAEPS ;  Q0I5K4, MTNN_HAES1 ;
DR   B0URX4, MTNN_HAES2 ;  C4K6C1, MTNN_HAMD5 ;  Q9ZMY2, MTNN_HELPJ ;
DR   O24915, MTNN_HELPY ;  B5Y1L0, MTNN_KLEP3 ;  A6T4W3, MTNN_KLEP7 ;
DR   Q9R4A1, MTNN_KLEPN ;  Q92BL9, MTNN_LISIN ;  C1KVE1, MTNN_LISMC ;
DR   Q71ZH6, MTNN_LISMF ;  B8DE17, MTNN_LISMH ;  Q8Y729, MTNN_LISMO ;
DR   A0AIU3, MTNN_LISW6 ;  B1HUJ1, MTNN_LYSSC ;  Q65SB6, MTNN_MANSM ;
DR   A6W3C9, MTNN_MARMS ;  P67657, MTNN_MYCBO ;  P67656, MTNN_MYCTU ;
DR   Q8EPT8, MTNN_OCEIH ;  Q9CP62, MTNN_PASMU ;  C6DC27, MTNN_PECCP ;
DR   Q7N841, MTNN_PHOLL ;  Q6LUR4, MTNN_PHOPR ;  B4EUF0, MTNN_PROMH ;
DR   Q3ILJ7, MTNN_PSEHT ;  A1STE7, MTNN_PSYIN ;  B5F8S1, MTNN_SALA4 ;
DR   A9MPK2, MTNN_SALAR ;  Q57T48, MTNN_SALCH ;  B5FJ06, MTNN_SALDC ;
DR   B5R3H1, MTNN_SALEP ;  B5RHE5, MTNN_SALG2 ;  B4TK35, MTNN_SALHS ;
DR   B4SUY9, MTNN_SALNS ;  Q5PD46, MTNN_SALPA ;  A9N0Q5, MTNN_SALPB ;
DR   C0Q5S0, MTNN_SALPC ;  B5BL87, MTNN_SALPK ;  B4TXR1, MTNN_SALSV ;
DR   P60216, MTNN_SALTI ;  P60217, MTNN_SALTY ;  A8G9V3, MTNN_SERP5 ;
DR   A1S3V6, MTNN_SHEAM ;  B8EBS7, MTNN_SHEB2 ;  A3D1T1, MTNN_SHEB5 ;
DR   A6WKN2, MTNN_SHEB8 ;  A9L5L1, MTNN_SHEB9 ;  Q12KE6, MTNN_SHEDO ;
DR   Q07YV9, MTNN_SHEFN ;  B0TIS5, MTNN_SHEHH ;  A3QBQ0, MTNN_SHELP ;
DR   Q8EHA7, MTNN_SHEON ;  A8H191, MTNN_SHEPA ;  A4Y4H9, MTNN_SHEPC ;
DR   B8CQP2, MTNN_SHEPW ;  A0KZQ7, MTNN_SHESA ;  A8FSA3, MTNN_SHESH ;
DR   Q0HG72, MTNN_SHESM ;  Q0HSG5, MTNN_SHESR ;  A1RMF2, MTNN_SHESW ;
DR   B1KI32, MTNN_SHEWM ;  B2U303, MTNN_SHIB3 ;  Q325Y0, MTNN_SHIBS ;
DR   Q32JU9, MTNN_SHIDS ;  Q0T847, MTNN_SHIF8 ;  P0AF15, MTNN_SHIFL ;
DR   Q3Z5J8, MTNN_SHISS ;  Q2NVP7, MTNN_SODGM ;  A7X306, MTNN_STAA1 ;
DR   A6U271, MTNN_STAA2 ;  Q2FGC5, MTNN_STAA3 ;  Q2FXX8, MTNN_STAA8 ;
DR   A5ITC6, MTNN_STAA9 ;  Q2YT29, MTNN_STAAB ;  Q5HFG2, MTNN_STAAC ;
DR   A6QHE1, MTNN_STAAE ;  Q99TQ0, MTNN_STAAM ;  Q7A5B0, MTNN_STAAN ;
DR   Q6GGA2, MTNN_STAAR ;  Q6G8W9, MTNN_STAAS ;  A8Z4D8, MTNN_STAAT ;
DR   Q7A0R5, MTNN_STAAW ;  B9DNJ2, MTNN_STACT ;  Q5HNU8, MTNN_STAEQ ;
DR   Q8CP08, MTNN_STAES ;  Q4L6V0, MTNN_STAHJ ;  Q49Y40, MTNN_STAS1 ;
DR   Q9X0L3, MTNN_THEMA ;  Q31DQ5, MTNN_THICR ;  C4LAP0, MTNN_TOLAT ;
DR   P96122, MTNN_TREPA ;  A5F5R2, MTNN_VIBC3 ;  Q9KPI8, MTNN_VIBCH ;
DR   C3LQF1, MTNN_VIBCM ;  Q5E2X3, MTNN_VIBF1 ;  A1IGA8, MTNN_VIBFI ;
DR   B5FAL1, MTNN_VIBFM ;  A7MXP2, MTNN_VIBHB ;  Q87SE5, MTNN_VIBPA ;
DR   B7VJ21, MTNN_VIBSL ;  Q8DEM9, MTNN_VIBVU ;  Q7MNT0, MTNN_VIBVY ;
DR   A1JJQ6, MTNN_YERE8 ;  A7FM04, MTNN_YERP3 ;  Q1C3X7, MTNN_YERPA ;
DR   B2K553, MTNN_YERPB ;  Q7CKD4, MTNN_YERPE ;  A9R1E0, MTNN_YERPG ;
DR   Q1CLU1, MTNN_YERPN ;  A4TPX2, MTNN_YERPP ;  Q66EE6, MTNN_YERPS ;
DR   B1JK17, MTNN_YERPY ;
//
ID   3.2.2.10
DE   Pyrimidine-5'-nucleotide nucleosidase.
AN   Pyr5N.
CA   A pyrimidine 5'-nucleotide + H(2)O = D-ribose 5-phosphate + a pyrimidine
CA   base.
CC   -!- Also acts on dUMP, dTMP and dCMP.
//
ID   3.2.2.11
DE   Beta-aspartyl-N-acetylglucosaminidase.
CA   1-beta-aspartyl-N-acetyl-D-glucosaminylamine + H(2)O = L-asparagine +
CA   N-acetyl-D-glucosamine.
//
ID   3.2.2.12
DE   Inosinate nucleosidase.
CA   5'-inosinate + H(2)O = D-ribose 5-phosphate + hypoxanthine.
//
ID   3.2.2.13
DE   1-methyladenosine nucleosidase.
CA   1-methyladenosine + H(2)O = 1-methyladenine + D-ribose.
//
ID   3.2.2.14
DE   NMN nucleosidase.
AN   NMNase.
CA   Nicotinamide D-ribonucleotide + H(2)O = D-ribose 5-phosphate +
CA   nicotinamide.
//
ID   3.2.2.15
DE   DNA-deoxyinosine glycosylase.
AN   DNA(hypoxanthine) glycohydrolase.
AN   DNA-deoxyinosine glycosidase.
CA   Hydrolyzes DNA and polynucleotides, releasing free hypoxanthine.
//
ID   3.2.2.16
DE   Methylthioadenosine nucleosidase.
AN   5'-methylthioadenosine nucleosidase.
AN   MeSAdo nucleosidase.
AN   Methylthioadenosine methylthioribohydrolase.
AN   MTA nucleosidase.
CA   S-methyl-5'-thioadenosine + H(2)O = S-methyl-5-thio-D-ribose + adenine.
CC   -!- Does not act on S-adenosylhomocysteine (cf. EC 3.2.2.9).
//
ID   3.2.2.17
DE   Deoxyribodipyrimidine endonucleosidase.
AN   Pyrimidine dimer DNA-glycosylase.
CA   Cleaves the N-glycosidic bond between the 5'-pyrimidine residue in
CA   cyclobutadipyrimidine (in DNA) and the corresponding deoxy-D-ribose
CA   residue.
//
ID   3.2.2.18
DE   Transferred entry: 3.5.1.52.
//
ID   3.2.2.19
DE   [Protein ADP-ribosylarginine] hydrolase.
AN   ADP-ribose-L-arginine cleavage enzyme.
AN   ADP-ribose-L-arginine cleaving enzyme.
AN   ADP-ribosylarginine hydrolase.
AN   N(omega)-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase.
CA   (1) Protein-N(omega)-(ADP-D-ribosyl)-L-arginine + H(2)O = ADP-ribose +
CA   protein-L-arginine.
CA   (2) N(omega)-(ADP-D-ribosyl)-L-arginine + H(2)O = ADP-ribose +
CA   L-arginine.
CC   -!- The enzyme will remove ADP-ribose from arginine residues in ADP-
CC       ribosylated proteins.
DR   Q32KR8, ADPRH_BOVIN;  P54922, ADPRH_HUMAN;  P54923, ADPRH_MOUSE;
DR   Q02589, ADPRH_RAT  ;  Q54H71, ADRPH_DICDI;
//
ID   3.2.2.20
DE   DNA-3-methyladenine glycosylase I.
AN   DNA glycosidase I.
AN   DNA-3-methyladenine glycosidase I.
CA   Hydrolysis of alkylated DNA, releasing 3-methyladenine.
PR   PROSITE; PDOC00447;
DR   P05100, 3MG1_ECOLI ;  P44321, 3MGA_HAEIN ;
//
ID   3.2.2.21
DE   DNA-3-methyladenine glycosylase II.
AN   DNA glycosidase II.
AN   DNA-3-methyladenine glycosidase II.
CA   Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine,
CA   7-methylguanine and 7-methyladenine.
PR   PROSITE; PDOC00447;
DR   P04395, 3MG2_ECOLI ;  P37878, 3MGA_BACSU ;  Q39147, 3MG_ARATH  ;
DR   Q8SQI1, 3MG_ENCCU  ;  P29372, 3MG_HUMAN  ;  Q04841, 3MG_MOUSE  ;
DR   P23571, 3MG_RAT    ;  Q10630, ALKA_MYCTU ;  Q92383, MAG1_SCHPO ;
DR   O94468, MAG2_SCHPO ;  P22134, MAG_YEAST  ;  O31544, YFJP_BACSU ;
//
ID   3.2.2.22
DE   rRNA N-glycosylase.
AN   rRNA N-glycosidase.
CA   Endohydrolysis of the N-glycosidic bond at one specific adenosine on the
CA   28S rRNA.
CC   -!- Ricin A-chain and related toxins show this activity.
CC   -!- Naked rRNA is attacked more slowly than rRNA in intact ribosomes.
CC   -!- Naked rRNA from Escherichia coli is cleaved at a corresponding
CC       position.
PR   PROSITE; PDOC00248;
DR   P11140, ABRA_ABRPR ;  Q06077, ABRB_ABRPR ;  P28590, ABRC_ABRPR ;
DR   Q06076, ABRD_ABRPR ;  Q9M6E9, AGGL_ABRPR ;  P06750, AGGL_RICCO ;
DR   P10593, ALB3_MAIZE ;  P83572, ARALA_ARAEL;  P84072, CHAR_MOMCH ;
DR   Q00531, JI60_HORVU ;  P36230, LECA_IRIHO ;  P81446, ML1_VISAL  ;
DR   Q6H266, ML2_VISAL  ;  P82683, ML3_VISAL  ;  Q6ITZ3, ML4_VISAL  ;
DR   P33183, NIGB_SAMNI ;  Q1JPL7, PME18_ARATH;  P02879, RICI_RICCO ;
DR   P24476, RIP0_DIACA ;  P33185, RIP1_BRYDI ;  Q9FRX4, RIP1_CUCFI ;
DR   Q5F0I3, RIP1_GYNPE ;  P22244, RIP1_HORVU ;  P56568, RIP1_LUFCY ;
DR   P16094, RIP1_MOMCH ;  P10297, RIP1_PHYAM ;  P93543, RIP1_SAMNI ;
DR   P98185, RIP1_SAPOF ;  P56626, RIP1_TRIAN ;  P98184, RIP2_BRYDI ;
DR   P24477, RIP2_DIACA ;  P04399, RIP2_HORVU ;  P29339, RIP2_MOMBA ;
DR   Q40772, RIP2_PHYAM ;  P34967, RIP2_PHYDI ;  P27559, RIP2_SAPOF ;
DR   P23029, RIP2_TRIKI ;  P25891, RIP3_MAIZE ;  P24817, RIP3_MOMCH ;
DR   P27560, RIP3_SAPOF ;  P24475, RIP3_SURMU ;  Q6EH50, RIP4_PHYHE ;
DR   P27561, RIP4_SAPOF ;  Q41389, RIP5_SAPOF ;  P20656, RIP6_SAPOF ;
DR   Q41391, RIP7_SAPOF ;  P25892, RIP9_MAIZE ;  Q7M1Z2, RIP9_SAPOF ;
DR   Q00465, RIPA_LUFCY ;  Q03464, RIPA_PHYAM ;  P22851, RIPB_LUFCY ;
DR   P86144, RIPD1_PHYDI;  P85208, RIPD2_PHYDI;  P33186, RIPG_SURMU ;
DR   P16093, RIPK_TRIKI ;  P84853, RIPL1_PHYDI;  P84854, RIPL2_PHYDI;
DR   P85101, RIPLY_LYCCH;  P84073, RIPL_LUFCY ;  P21326, RIPP_MIRJA ;
DR   P20655, RIPS_MOMCO ;  P23339, RIPS_PHYAM ;  P24478, RIPS_TRIKI ;
DR   P09989, RIPT_TRIKI ;  P80750, RIPX_CUCPE ;  P28522, RIPX_MAIZE ;
DR   P84531, RIP_CUCMO  ;  P84786, RIP_DRIMA  ;  P83324, RIP_FLAVE  ;
DR   P84530, RIP_LUFAC  ;  P83245, RIP_PLETU  ;  P83323, RIP_SIRGR  ;
DR   Q779K4, STXA_BP788 ;  P09385, STXA_BP933 ;  P08026, STXA_BPH19 ;
DR   P10149, STXA_BPH30 ;  Q32GM1, STXA_SHIDS ;  Q9FBI2, STXA_SHIDY ;
//
ID   3.2.2.23
DE   DNA-formamidopyrimidine glycosylase.
AN   Fapy-DNA glycosylase.
AN   Formamidopyrimidine-DNA glycosylase.
CA   Hydrolysis of DNA containing ring-opened 7-methylguanine residues,
CA   releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine.
CC   -!- May play a significant role in processes leading to recovery from
CC       mutagenesis and/or cell death by alkylating agents.
CC   -!- Also involved in the GO system responsible for removing an
CC       oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from
CC       DNA.
PR   PROSITE; PDOC00956;
DR   B0C5D4, FPG_ACAM1  ;  Q6FE90, FPG_ACIAD  ;  B0VRV3, FPG_ACIBS  ;
DR   A0LV85, FPG_ACIC1  ;  A5FZ95, FPG_ACICJ  ;  B9ME52, FPG_ACIET  ;
DR   B7J8I7, FPG_ACIF2  ;  B5ENT6, FPG_ACIF5  ;  A1W4G6, FPG_ACISJ  ;
DR   A3N3S8, FPG_ACTP2  ;  B3GZD6, FPG_ACTP7  ;  B0BU16, FPG_ACTPJ  ;
DR   A6VKA1, FPG_ACTSZ  ;  A0KEN2, FPG_AERHH  ;  A4STD1, FPG_AERS4  ;
DR   Q8UIH4, FPG_AGRT5  ;  B9JZF5, FPG_AGRVS  ;  Q0VLB7, FPG_ALCBS  ;
DR   Q0A598, FPG_ALHEH  ;  B4S2C6, FPG_ALTMD  ;  Q3MDP1, FPG_ANAVT  ;
DR   Q5P728, FPG_AROAE  ;  A8IQM5, FPG_AZOC5  ;  Q81L04, FPG_BACAN  ;
DR   Q72ZF1, FPG_BACC1  ;  Q817G5, FPG_BACCR  ;  Q633L1, FPG_BACCZ  ;
DR   P19210, FPG_BACFI  ;  Q9K855, FPG_BACHD  ;  Q6HCU5, FPG_BACHK  ;
DR   Q65G93, FPG_BACLD  ;  Q5WEG7, FPG_BACSK  ;  O34403, FPG_BACSU  ;
DR   A1UU20, FPG_BARBK  ;  Q6G4T2, FPG_BARHE  ;  Q6G0L3, FPG_BARQU  ;
DR   A9IN26, FPG_BART1  ;  Q1LTS6, FPG_BAUCH  ;  Q6ML45, FPG_BDEBA  ;
DR   B2IE81, FPG_BEII9  ;  Q2KYB7, FPG_BORA1  ;  Q7W185, FPG_BORPA  ;
DR   A9I6Y3, FPG_BORPD  ;  Q7VUG7, FPG_BORPE  ;  Q89WC9, FPG_BRAJA  ;
DR   A5E887, FPG_BRASB  ;  A4YJG9, FPG_BRASO  ;  C0Z7Z0, FPG_BREBN  ;
DR   B2S9T2, FPG_BRUA1  ;  Q2YQP8, FPG_BRUA2  ;  Q57A83, FPG_BRUAB  ;
DR   A9MAB2, FPG_BRUC2  ;  C0RG65, FPG_BRUMB  ;  Q8YED2, FPG_BRUME  ;
DR   A5VTD0, FPG_BRUO2  ;  Q8FXR6, FPG_BRUSU  ;  B1YN48, FPG_BURA4  ;
DR   Q1BTH0, FPG_BURCA  ;  A0KAM1, FPG_BURCH  ;  B4EAR7, FPG_BURCJ  ;
DR   A9AEZ2, FPG_BURM1  ;  A2S6C0, FPG_BURM9  ;  Q62FC7, FPG_BURMA  ;
DR   A1UZN2, FPG_BURMS  ;  A3NRA1, FPG_BURP0  ;  Q3JW82, FPG_BURP1  ;
DR   A3N5K5, FPG_BURP6  ;  B2JCP3, FPG_BURP8  ;  B2SXG9, FPG_BURPP  ;
DR   Q63XL4, FPG_BURPS  ;  Q39CU4, FPG_BURS3  ;  Q2T1B3, FPG_BURTA  ;
DR   A4JHZ1, FPG_BURVG  ;  Q145W8, FPG_BURXL  ;  Q3ABL4, FPG_CARHZ  ;
DR   B8GVY4, FPG_CAUCN  ;  Q9A259, FPG_CAUCR  ;  B0T7D1, FPG_CAUSK  ;
DR   B3PG51, FPG_CELJU  ;  A9WDC2, FPG_CHLAA  ;  B8G9X1, FPG_CHLAD  ;
DR   Q7NQS5, FPG_CHRVO  ;  A8ARM2, FPG_CITK8  ;  Q48AD4, FPG_COLP3  ;
DR   C3PH91, FPG_CORA7  ;  Q6NGH4, FPG_CORDI  ;  Q8FP17, FPG_COREF  ;
DR   A4QFD9, FPG_CORGB  ;  Q8NNV7, FPG_CORGL  ;  Q4JUY8, FPG_CORJK  ;
DR   B1VG60, FPG_CORU7  ;  Q0KEP4, FPG_CUPNH  ;  Q476F5, FPG_CUPPJ  ;
DR   B2AGU2, FPG_CUPTR  ;  B1WTF7, FPG_CYAA5  ;  B7K1T1, FPG_CYAP8  ;
DR   Q479M6, FPG_DECAR  ;  Q9RX22, FPG_DEIRA  ;  C6BUX8, FPG_DESAD  ;
DR   B8FU83, FPG_DESHD  ;  Q24XW2, FPG_DESHY  ;  Q6APT2, FPG_DESPS  ;
DR   A4J4X3, FPG_DESRM  ;  Q726D5, FPG_DESVH  ;  A5EXK6, FPG_DICNV  ;
DR   A8LNK8, FPG_DINSH  ;  A7ZTI6, FPG_ECO24  ;  B7ULJ0, FPG_ECO27  ;
DR   B7MFJ6, FPG_ECO45  ;  B7L758, FPG_ECO55  ;  P64148, FPG_ECO57  ;
DR   B5YWD3, FPG_ECO5E  ;  B7NPE1, FPG_ECO7I  ;  B7N2X1, FPG_ECO81  ;
DR   B7M4B9, FPG_ECO8A  ;  C4ZXM7, FPG_ECOBW  ;  B1X969, FPG_ECODH  ;
DR   A8A697, FPG_ECOHS  ;  A1AHG8, FPG_ECOK1  ;  Q0TBH4, FPG_ECOL5  ;
DR   Q8FC87, FPG_ECOL6  ;  B1IZF8, FPG_ECOLC  ;  P05523, FPG_ECOLI  ;
DR   B7NET9, FPG_ECOLU  ;  B6I3L2, FPG_ECOSE  ;  B1LK72, FPG_ECOSM  ;
DR   Q1R4V8, FPG_ECOUT  ;  C5B9D8, FPG_EDWI9  ;  A4W514, FPG_ENT38  ;
DR   Q837G3, FPG_ENTFA  ;  A7MQ97, FPG_ENTS8  ;  Q6DAV4, FPG_ERWCT  ;
DR   B2VF70, FPG_ERWT9  ;  Q2N7Y8, FPG_ERYLH  ;  B7LVJ6, FPG_ESCF3  ;
DR   B1YKA0, FPG_EXIS2  ;  C4L470, FPG_EXISA  ;  A8L594, FPG_FRASN  ;
DR   Q5NGY3, FPG_FRATT  ;  Q5KWC3, FPG_GEOKA  ;  Q39WD1, FPG_GEOMG  ;
DR   B9M5V2, FPG_GEOSF  ;  Q74EG5, FPG_GEOSL  ;  A5G7Q9, FPG_GEOUR  ;
DR   Q7NFW7, FPG_GLOVI  ;  A9HI30, FPG_GLUDA  ;  Q5FN17, FPG_GLUOX  ;
DR   Q7VN67, FPG_HAEDU  ;  Q4QLW2, FPG_HAEI8  ;  A5UDC3, FPG_HAEIE  ;
DR   A5UI87, FPG_HAEIG  ;  P44948, FPG_HAEIN  ;  B8F586, FPG_HAEPS  ;
DR   Q0I0X6, FPG_HAES1  ;  B0UUX0, FPG_HAES2  ;  Q2SPF3, FPG_HAHCH  ;
DR   A1WZG2, FPG_HALHL  ;  B0TER7, FPG_HELMI  ;  A9B0X2, FPG_HERA2  ;
DR   A4G916, FPG_HERAR  ;  Q5QZC1, FPG_IDILO  ;  A6T2R7, FPG_JANMA  ;
DR   Q28JI5, FPG_JANSC  ;  A6W7S6, FPG_KINRD  ;  B5XTG8, FPG_KLEP3  ;
DR   A6TFM6, FPG_KLEP7  ;  Q5FIV8, FPG_LACAC  ;  Q1G9A3, FPG_LACDA  ;
DR   Q049F3, FPG_LACDB  ;  Q041U1, FPG_LACGA  ;  A8YWE6, FPG_LACH4  ;
DR   Q74IB5, FPG_LACJO  ;  Q9CIK4, FPG_LACLA  ;  P42371, FPG_LACLC  ;
DR   Q88WV4, FPG_LACPL  ;  Q1WUN7, FPG_LACS1  ;  Q38VS5, FPG_LACSS  ;
DR   C1DBB4, FPG_LARHH  ;  Q5X7I9, FPG_LEGPA  ;  Q5ZY18, FPG_LEGPH  ;
DR   Q5WYY6, FPG_LEGPL  ;  Q6AFJ3, FPG_LEIXX  ;  B1Y3P5, FPG_LEPCP  ;
DR   Q92BF1, FPG_LISIN  ;  Q71ZA3, FPG_LISMF  ;  Q8Y6W7, FPG_LISMO  ;
DR   A0L837, FPG_MAGSM  ;  Q65R59, FPG_MANSM  ;  A1U749, FPG_MARAV  ;
DR   A6VSY6, FPG_MARMS  ;  Q11AV8, FPG_MESSB  ;  B7KN75, FPG_METC4  ;
DR   Q602J1, FPG_METCA  ;  A9W8R7, FPG_METEP  ;  Q1H3I3, FPG_METFK  ;
DR   B8IIZ9, FPG_METNO  ;  B1ZGU8, FPG_METPB  ;  B1LWY6, FPG_METRJ  ;
DR   B0UR68, FPG_METS4  ;  B8EKR5, FPG_METSB  ;  Q5UQ00, FPG_MIMIV  ;
DR   Q2RHE9, FPG_MOOTA  ;  A0QJ66, FPG_MYCA1  ;  B1MDL2, FPG_MYCA9  ;
DR   P64151, FPG_MYCBO  ;  A1KMR9, FPG_MYCBP  ;  C1AG40, FPG_MYCBT  ;
DR   P55825, FPG_MYCGE  ;  A4TE57, FPG_MYCGI  ;  B8ZRZ2, FPG_MYCLB  ;
DR   O69470, FPG_MYCLE  ;  B2HJJ6, FPG_MYCMM  ;  Q6KHS0, FPG_MYCMO  ;
DR   Q73VL9, FPG_MYCPA  ;  P75402, FPG_MYCPN  ;  Q98QQ1, FPG_MYCPU  ;
DR   A0QV21, FPG_MYCS2  ;  A3PXU1, FPG_MYCSJ  ;  A1UED7, FPG_MYCSK  ;
DR   Q1BAM5, FPG_MYCSS  ;  A5U6T0, FPG_MYCTA  ;  P64150, FPG_MYCTU  ;
DR   A0PQ49, FPG_MYCUA  ;  A1T737, FPG_MYCVP  ;  Q5F8Z9, FPG_NEIG1  ;
DR   P57014, FPG_NEIMA  ;  P55044, FPG_NEIMB  ;  Q0AD66, FPG_NITEC  ;
DR   Q82S12, FPG_NITEU  ;  Q2YBI1, FPG_NITMU  ;  Q3J7U5, FPG_NITOC  ;
DR   Q3SWN3, FPG_NITWN  ;  Q5YS09, FPG_NOCFA  ;  A1SLU7, FPG_NOCSJ  ;
DR   B2J5G0, FPG_NOSP7  ;  Q8YP80, FPG_NOSS1  ;  Q2GAT0, FPG_NOVAD  ;
DR   Q8EPE6, FPG_OCEIH  ;  B6JCQ7, FPG_OLICO  ;  A1BAN2, FPG_PARDP  ;
DR   A7HZC4, FPG_PARL1  ;  Q6MCT3, FPG_PARUW  ;  P57910, FPG_PASMU  ;
DR   Q8VW76, FPG_PASPI  ;  C6DIB8, FPG_PECCP  ;  Q03GC2, FPG_PEDPA  ;
DR   Q3A3F2, FPG_PELCD  ;  A1AV29, FPG_PELPD  ;  A5D0T6, FPG_PELTS  ;
DR   B4RC43, FPG_PHEZH  ;  Q7MY36, FPG_PHOLL  ;  Q6LVN0, FPG_PHOPR  ;
DR   A1VKP2, FPG_POLNA  ;  B1XS61, FPG_POLNS  ;  Q12DZ5, FPG_POLSJ  ;
DR   A3PB53, FPG_PROM0  ;  A2C0H4, FPG_PROM1  ;  A8G2Y9, FPG_PROM2  ;
DR   A9BDY5, FPG_PROM4  ;  A2BUV8, FPG_PROM5  ;  Q31CK0, FPG_PROM9  ;
DR   Q7VDK6, FPG_PROMA  ;  B4F0X6, FPG_PROMH  ;  Q7V8Y5, FPG_PROMM  ;
DR   Q7V2X4, FPG_PROMP  ;  A2BPD1, FPG_PROMS  ;  Q46H41, FPG_PROMT  ;
DR   Q48CK1, FPG_PSE14  ;  Q15ZV5, FPG_PSEA6  ;  A6UYG0, FPG_PSEA7  ;
DR   B7V2S0, FPG_PSEA8  ;  Q02U58, FPG_PSEAB  ;  Q9L7T2, FPG_PSEAE  ;
DR   Q1IGF3, FPG_PSEE4  ;  Q4K4A5, FPG_PSEF5  ;  C3K3N6, FPG_PSEFS  ;
DR   A4Y028, FPG_PSEMY  ;  A5WAF9, FPG_PSEP1  ;  Q3K566, FPG_PSEPF  ;
DR   B0KN79, FPG_PSEPG  ;  Q88CQ5, FPG_PSEPK  ;  B1J2M4, FPG_PSEPW  ;
DR   Q88AH6, FPG_PSESM  ;  Q4ZM34, FPG_PSEU2  ;  A4VRM9, FPG_PSEU5  ;
DR   Q4FUU7, FPG_PSYA2  ;  A1SR12, FPG_PSYIN  ;  Q1LRP7, FPG_RALME  ;
DR   B2UES0, FPG_RALPJ  ;  Q8Y2D7, FPG_RALSO  ;  B3PZ93, FPG_RHIE6  ;
DR   Q2KDA9, FPG_RHIEC  ;  Q1MMD9, FPG_RHIL3  ;  Q98BG6, FPG_RHILO  ;
DR   B5ZYK9, FPG_RHILW  ;  Q59752, FPG_RHIME  ;  C3MCY7, FPG_RHISN  ;
DR   B6IVU4, FPG_RHOCS  ;  C0ZXQ5, FPG_RHOE4  ;  Q21XW7, FPG_RHOFD  ;
DR   C1B2Q5, FPG_RHOOB  ;  Q2J2I0, FPG_RHOP2  ;  Q07UF4, FPG_RHOP5  ;
DR   Q6NDM1, FPG_RHOPA  ;  Q21CD4, FPG_RHOPB  ;  Q13EN7, FPG_RHOPS  ;
DR   B3Q620, FPG_RHOPT  ;  Q2RMQ2, FPG_RHORT  ;  A3PFL2, FPG_RHOS1  ;
DR   Q3IY64, FPG_RHOS4  ;  A4WVR6, FPG_RHOS5  ;  B9KQJ9, FPG_RHOSK  ;
DR   Q0S2E0, FPG_RHOSR  ;  C3PLF5, FPG_RICAE  ;  A8GXR0, FPG_RICB8  ;
DR   Q1RJY6, FPG_RICBR  ;  A8EZP5, FPG_RICCK  ;  Q92GT4, FPG_RICCN  ;
DR   Q4UMW5, FPG_RICFE  ;  A8F2H0, FPG_RICM5  ;  C4K2K4, FPG_RICPU  ;
DR   B0BUU0, FPG_RICRO  ;  A8GTA0, FPG_RICRS  ;  A7NQM8, FPG_ROSCS  ;
DR   Q16DL0, FPG_ROSDO  ;  A5UUN1, FPG_ROSS1  ;  A1AW02, FPG_RUTMC  ;
DR   Q21EE3, FPG_SACD2  ;  A4FMJ7, FPG_SACEN  ;  B5EXE0, FPG_SALA4  ;
DR   A8M661, FPG_SALAI  ;  A9MKN9, FPG_SALAR  ;  Q57IA7, FPG_SALCH  ;
DR   B5FM59, FPG_SALDC  ;  B5R5F9, FPG_SALEP  ;  B5RGF2, FPG_SALG2  ;
DR   B4T9C0, FPG_SALHS  ;  B4SXD7, FPG_SALNS  ;  Q5PC09, FPG_SALPA  ;
DR   A9MVN0, FPG_SALPB  ;  C0Q1W8, FPG_SALPC  ;  B5BI09, FPG_SALPK  ;
DR   B4TZX7, FPG_SALSV  ;  Q8Z2H2, FPG_SALTI  ;  A4X4F8, FPG_SALTO  ;
DR   O54326, FPG_SALTY  ;  Q9X981, FPG_SERMA  ;  A8GLE2, FPG_SERP5  ;
DR   A1S1S3, FPG_SHEAM  ;  B8EDQ9, FPG_SHEB2  ;  A3CYP7, FPG_SHEB5  ;
DR   A6WUE9, FPG_SHEB8  ;  A9KW47, FPG_SHEB9  ;  Q12SR9, FPG_SHEDO  ;
DR   B0TN04, FPG_SHEHH  ;  A3QJA8, FPG_SHELP  ;  Q8E8D9, FPG_SHEON  ;
DR   A8HA27, FPG_SHEPA  ;  B8CVD1, FPG_SHEPW  ;  A0L2N2, FPG_SHESA  ;
DR   Q0HDC3, FPG_SHESM  ;  Q0HPK4, FPG_SHESR  ;  A1RE25, FPG_SHESW  ;
DR   B1KL38, FPG_SHEWM  ;  B2TTU9, FPG_SHIB3  ;  Q31UZ1, FPG_SHIBS  ;
DR   Q329M2, FPG_SHIDS  ;  Q0SYG3, FPG_SHIF8  ;  P64149, FPG_SHIFL  ;
DR   Q3YVZ7, FPG_SHISS  ;  Q5LWT9, FPG_SILPO  ;  Q1GC55, FPG_SILST  ;
DR   A6UFF8, FPG_SINMW  ;  Q2NQU4, FPG_SODGM  ;  Q01RU9, FPG_SOLUE  ;
DR   Q1GN82, FPG_SPHAL  ;  A5VG06, FPG_SPHWW  ;  Q3K028, FPG_STRA1  ;
DR   P64152, FPG_STRA3  ;  P64153, FPG_STRA5  ;  Q82JU0, FPG_STRAW  ;
DR   Q9ZBQ6, FPG_STRCO  ;  B1VYY1, FPG_STRGG  ;  B4SRN0, FPG_STRM5  ;
DR   B2FU49, FPG_STRMK  ;  P55045, FPG_STRMU  ;  Q9A131, FPG_STRP1  ;
DR   P0DB14, FPG_STRP3  ;  Q5XDE4, FPG_STRP6  ;  Q8P250, FPG_STRP8  ;
DR   Q48UU6, FPG_STRPM  ;  Q97R61, FPG_STRPN  ;  P0DB15, FPG_STRPQ  ;
DR   Q8DQ33, FPG_STRR6  ;  Q5M0P0, FPG_STRT1  ;  Q5M576, FPG_STRT2  ;
DR   Q67R59, FPG_SYMTH  ;  P95744, FPG_SYNEN  ;  Q08079, FPG_SYNP6  ;
DR   Q7U4V2, FPG_SYNPX  ;  Q0AVE3, FPG_SYNWW  ;  P74290, FPG_SYNY3  ;
DR   C5BLG1, FPG_TERTT  ;  P59065, FPG_THEEB  ;  Q47S77, FPG_THEFY  ;
DR   B9L1Z5, FPG_THERP  ;  Q72HN2, FPG_THET2  ;  O50606, FPG_THET8  ;
DR   Q31EB2, FPG_THICR  ;  Q3SLR9, FPG_THIDA  ;  B8GUQ6, FPG_THISH  ;
DR   Q117D2, FPG_TRIEI  ;  Q9PQ76, FPG_UREPA  ;  C5CYZ1, FPG_VARPS  ;
DR   A5CX90, FPG_VESOH  ;  A5F407, FPG_VIBC3  ;  Q9KVC5, FPG_VIBCH  ;
DR   C3LQI3, FPG_VIBCM  ;  Q5E8M1, FPG_VIBF1  ;  B5FFG1, FPG_VIBFM  ;
DR   A7MSN3, FPG_VIBHB  ;  Q87T81, FPG_VIBPA  ;  B7VHK6, FPG_VIBSL  ;
DR   Q8DDY4, FPG_VIBVU  ;  Q7MPS3, FPG_VIBVY  ;  Q73G10, FPG_WOLPM  ;
DR   B3CM71, FPG_WOLPP  ;  Q5GS47, FPG_WOLTR  ;  C0R4I6, FPG_WOLWR  ;
DR   Q8PEQ4, FPG_XANAC  ;  Q3BM92, FPG_XANC5  ;  Q4UNU6, FPG_XANC8  ;
DR   B0RZ50, FPG_XANCB  ;  Q8P3C4, FPG_XANCP  ;  Q2P8V2, FPG_XANOM  ;
DR   B2STU3, FPG_XANOP  ;  Q5H667, FPG_XANOR  ;  A7IKJ3, FPG_XANP2  ;
DR   P64154, FPG_XYLFA  ;  P64155, FPG_XYLFT  ;  A1JHR7, FPG_YERE8  ;
DR   A7FCT7, FPG_YERP3  ;  Q1C270, FPG_YERPA  ;  B2JYN6, FPG_YERPB  ;
DR   Q8ZJP0, FPG_YERPE  ;  A9R677, FPG_YERPG  ;  Q1CD05, FPG_YERPN  ;
DR   A4TSD4, FPG_YERPP  ;  Q66GD3, FPG_YERPS  ;  B1JQX0, FPG_YERPY  ;
DR   Q9X3X1, FPG_ZYMMO  ;
//
ID   3.2.2.24
DE   ADP-ribosyl-[dinitrogen reductase] hydrolase.
AN   ADP-ribosyl glycohydrolase.
AN   Dinitrogenase reductase activating glycohydrolase.
CA   ADP-D-ribosyl-[dinitrogen reductase] = ADP-D-ribose + [dinitrogen
CA   reductase].
CC   -!- Together with EC 2.4.2.37, controls the level of activity of
CC       EC 1.18.6.1.
DR   P14300, DRAG_RHORU ;
//
ID   3.2.2.25
DE   N-methyl nucleosidase.
AN   7-methylxanthosine nucleosidase.
AN   Methylpurine nucleosidase.
AN   N-meNase.
AN   N-methyl nucleoside hydrolase.
CA   7-methylxanthosine + H(2)O = 7-methylxanthine + D-ribose.
CC   -!- Preferentially hydrolyzes 3- and 7-methylpurine nucleosides, such as
CC       3-methylxanthosine, 3-methyladenosine and 7-methylguanosine.
CC   -!- Hydrolysis of 7-methylxanthosine to form 7-methylxanthine is the
CC       second step in the caffeine biosynthesis pathway.
//
ID   3.2.2.26
DE   Futalosine hydrolase.
AN   Futalosine nucleosidase.
CA   Futalosine + H(2)O = dehypoxanthine futalosine + hypoxanthine.
CC   -!- This enzyme, which is specific for futalosine, catalyzes the second
CC       step of a novel menaquinone biosynthetic pathway that is found in
CC       some prokaryotes.
//
ID   3.2.2.27
DE   Uracil-DNA glycosylase.
AN   Uracil DNA glycohydrolase.
AN   Uracil-DNA N-glycosylase.
CA   Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and
CA   polynucleotides, releasing free uracil.
CC   -!- Uracil-DNA glycosylases are widespread enzymes that are found in all
CC       living organisms.
CC   -!- Uracil-DNA glycosylase (EC 3.2.2.27) and double-stranded uracil-DNA
CC       glycosylase (EC 3.2.2.28) form a central part of the DNA-repair
CC       machinery since they initiate the DNA base-excision repair pathway by
CC       hydrolyzing the N-glycosidic bond between uracil and the deoxyribose
CC       sugar thereby catalyzing the removal of mis-incorporated uracil from
CC       DNA.
PR   PROSITE; PDOC00121;
DR   P16769, UL114_HCMVA;  Q5LA67, UNG1_BACFN ;  Q64QI5, UNG1_BACFR ;
DR   Q92EQ0, UNG1_LISIN ;  Q723S4, UNG1_LISMF ;  Q8Y9X7, UNG1_LISMO ;
DR   Q82MX6, UNG1_STRAW ;  Q9EX12, UNG1_STRCO ;  Q5L9D9, UNG2_BACFN ;
DR   Q64PM3, UNG2_BACFR ;  Q92CI1, UNG2_LISIN ;  Q720K2, UNG2_LISMF ;
DR   Q8Y7P6, UNG2_LISMO ;  Q827B3, UNG2_STRAW ;  Q9K3Z0, UNG2_STRCO ;
DR   Q6F9Y2, UNG_ACIAD  ;  B7H3L4, UNG_ACIB3  ;  B7I526, UNG_ACIB5  ;
DR   B2HZE0, UNG_ACIBC  ;  B0VMZ7, UNG_ACIBS  ;  A3M500, UNG_ACIBT  ;
DR   B0VD25, UNG_ACIBY  ;  A3MZ80, UNG_ACTP2  ;  B3H0M4, UNG_ACTP7  ;
DR   B0BTB4, UNG_ACTPJ  ;  A6VLV4, UNG_ACTSZ  ;  A0KMZ1, UNG_AERHH  ;
DR   A4SK71, UNG_AERS4  ;  Q8UCM8, UNG_AGRT5  ;  O36395, UNG_ALHV1  ;
DR   B6EKY3, UNG_ALISL  ;  A6TVW5, UNG_ALKMQ  ;  A8MM35, UNG_ALKOO  ;
DR   B3ERG6, UNG_AMOA5  ;  B7GMM1, UNG_ANOFW  ;  A8EWN8, UNG_ARCB4  ;
DR   B6YR15, UNG_AZOPC  ;  C1DQR0, UNG_AZOVD  ;  A7ZA24, UNG_BACA2  ;
DR   C3P2F8, UNG_BACAA  ;  C3LFS7, UNG_BACAC  ;  A0RLI1, UNG_BACAH  ;
DR   Q81JQ4, UNG_BACAN  ;  B7JHM3, UNG_BACC0  ;  Q72X51, UNG_BACC1  ;
DR   B7IRS8, UNG_BACC2  ;  C1EQ68, UNG_BACC3  ;  B7HG60, UNG_BACC4  ;
DR   B7HYF9, UNG_BACC7  ;  A7GVE5, UNG_BACCN  ;  B9IS32, UNG_BACCQ  ;
DR   Q814M9, UNG_BACCR  ;  Q630K2, UNG_BACCZ  ;  Q9K682, UNG_BACHD  ;
DR   Q6HAN7, UNG_BACHK  ;  Q65DN9, UNG_BACLD  ;  A8FIM7, UNG_BACP2  ;
DR   Q5WAZ9, UNG_BACSK  ;  P39615, UNG_BACSU  ;  Q8A5V6, UNG_BACTN  ;
DR   A6L7T5, UNG_BACV8  ;  A9VSJ0, UNG_BACWK  ;  P53764, UNG_BHV1C  ;
DR   Q8G3E9, UNG_BIFLO  ;  Q7VRQ7, UNG_BLOFL  ;  Q2L0Y2, UNG_BORA1  ;
DR   Q0SPB2, UNG_BORAP  ;  Q7WQW5, UNG_BORBR  ;  O51082, UNG_BORBU  ;
DR   B7J0Y9, UNG_BORBZ  ;  B5RKV2, UNG_BORDL  ;  Q662W1, UNG_BORGA  ;
DR   B2S1N8, UNG_BORHD  ;  Q7W1Y7, UNG_BORPA  ;  A9IGW1, UNG_BORPD  ;
DR   Q7VUM8, UNG_BORPE  ;  B5RQN2, UNG_BORRA  ;  A1QYK3, UNG_BORT9  ;
DR   C0Z887, UNG_BREBN  ;  P57280, UNG_BUCAI  ;  B8D787, UNG_BUCAT  ;
DR   P59465, UNG_BUCBP  ;  Q057V4, UNG_BUCCC  ;  A7ZAZ4, UNG_CAMC1  ;
DR   A7GVX1, UNG_CAMC5  ;  A0RM89, UNG_CAMFF  ;  A7I0A8, UNG_CAMHC  ;
DR   A8FJP1, UNG_CAMJ8  ;  A7H1G3, UNG_CAMJD  ;  Q9PJ40, UNG_CAMJE  ;
DR   A1VXG9, UNG_CAMJJ  ;  Q5HX80, UNG_CAMJR  ;  B9KEK7, UNG_CAMLR  ;
DR   Q5L4Q4, UNG_CHLAB  ;  Q821F7, UNG_CHLCV  ;  Q256I7, UNG_CHLFF  ;
DR   Q9PJD2, UNG_CHLMU  ;  Q9Z7D3, UNG_CHLPN  ;  B0B8I2, UNG_CHLT2  ;
DR   Q3KL88, UNG_CHLTA  ;  B0BA61, UNG_CHLTB  ;  O84613, UNG_CHLTR  ;
DR   Q7P1I1, UNG_CHRVO  ;  A8AD07, UNG_CITK8  ;  A6M317, UNG_CLOB8  ;
DR   B2V017, UNG_CLOBA  ;  B2TQZ9, UNG_CLOBB  ;  Q182G9, UNG_CLOD6  ;
DR   Q0TUH0, UNG_CLOP1  ;  Q8XNR7, UNG_CLOPE  ;  A9KP29, UNG_CLOPH  ;
DR   Q0SWB8, UNG_CLOPS  ;  Q8FPQ4, UNG_COREF  ;  Q8NQU9, UNG_CORGL  ;
DR   B6J738, UNG_COXB1  ;  B6J089, UNG_COXB2  ;  A9KCD5, UNG_COXBN  ;
DR   Q83CW4, UNG_COXBU  ;  C1CXS7, UNG_DEIDV  ;  Q1IWN1, UNG_DEIGD  ;
DR   Q9RWH9, UNG_DEIRA  ;  Q315T1, UNG_DESDG  ;  B8FSV8, UNG_DESHD  ;
DR   Q24YA3, UNG_DESHY  ;  P53766, UNG_DICDI  ;  A5EVB8, UNG_DICNV  ;
DR   P12888, UNG_EBVB9  ;  A7ZQ25, UNG_ECO24  ;  B7UH19, UNG_ECO27  ;
DR   B7MIR5, UNG_ECO45  ;  B7LDH3, UNG_ECO55  ;  Q8X444, UNG_ECO57  ;
DR   B5Z154, UNG_ECO5E  ;  B7NRN6, UNG_ECO7I  ;  B7MYL3, UNG_ECO81  ;
DR   B7M8J5, UNG_ECO8A  ;  C4ZYK3, UNG_ECOBW  ;  B1XBQ7, UNG_ECODH  ;
DR   A8A392, UNG_ECOHS  ;  A1AEB0, UNG_ECOK1  ;  Q0TEQ8, UNG_ECOL5  ;
DR   Q8FF08, UNG_ECOL6  ;  B1IVP7, UNG_ECOLC  ;  P12295, UNG_ECOLI  ;
DR   B7N6H1, UNG_ECOLU  ;  B6I5F5, UNG_ECOSE  ;  B1LP93, UNG_ECOSM  ;
DR   Q1R8F2, UNG_ECOUT  ;  P28866, UNG_EHV1B  ;  P69859, UNG_EHV1V  ;
DR   P53765, UNG_EHV2   ;  A4WDE9, UNG_ENT38  ;  Q836Z5, UNG_ENTFA  ;
DR   Q6D208, UNG_ERWCT  ;  B2VEC7, UNG_ERWT9  ;  B7LUY5, UNG_ESCF3  ;
DR   C4Z8Z2, UNG_EUBR3  ;  B1YFL0, UNG_EXIS2  ;  A5FFT1, UNG_FLAJ1  ;
DR   P21968, UNG_FOWPN  ;  B0TXF5, UNG_FRAP2  ;  A8LD98, UNG_FRASN  ;
DR   Q14G45, UNG_FRAT1  ;  A7NAN4, UNG_FRATF  ;  Q2A4Q4, UNG_FRATH  ;
DR   B2SFW5, UNG_FRATM  ;  A0Q7Y8, UNG_FRATN  ;  Q0BN28, UNG_FRATO  ;
DR   Q5NEP2, UNG_FRATT  ;  A4IWI7, UNG_FRATW  ;  Q8R634, UNG_FUSNN  ;
DR   Q9E6R2, UNG_GAHVM  ;  Q5KUD0, UNG_GEOKA  ;  C5D9T3, UNG_GEOSW  ;
DR   A4ITQ2, UNG_GEOTN  ;  A0M1V1, UNG_GRAFK  ;  Q7VMC0, UNG_HAEDU  ;
DR   Q4QPM6, UNG_HAEI8  ;  A5UBC0, UNG_HAEIE  ;  P43731, UNG_HAEIN  ;
DR   B8F6C3, UNG_HAEPS  ;  Q0I271, UNG_HAES1  ;  B0UWA7, UNG_HAES2  ;
DR   Q17Z05, UNG_HELAH  ;  Q7VGS1, UNG_HELHP  ;  B6JNI4, UNG_HELP2  ;
DR   B5Z8Z4, UNG_HELPG  ;  Q1CRR1, UNG_HELPH  ;  Q9ZJN9, UNG_HELPJ  ;
DR   B2UVB0, UNG_HELPS  ;  P56397, UNG_HELPY  ;  P10186, UNG_HHV11  ;
DR   P13158, UNG_HHV23  ;  P28275, UNG_HHV2H  ;  P52345, UNG_HHV6U  ;
DR   P52447, UNG_HHV6Z  ;  P50639, UNG_HHV7J  ;  P13051, UNG_HUMAN  ;
DR   Q5R080, UNG_IDILO  ;  B5XNF8, UNG_KLEP3  ;  A6TCJ2, UNG_KLEP7  ;
DR   Q5FL46, UNG_LACAC  ;  Q03SK6, UNG_LACBA  ;  Q03AI1, UNG_LACC3  ;
DR   B3WCZ5, UNG_LACCB  ;  Q1GB22, UNG_LACDA  ;  Q04BG7, UNG_LACDB  ;
DR   B2GAM7, UNG_LACF3  ;  A8YUE7, UNG_LACH4  ;  Q74K70, UNG_LACJO  ;
DR   Q9CIX2, UNG_LACLA  ;  A2RHW2, UNG_LACLM  ;  Q032L5, UNG_LACLS  ;
DR   Q88YG1, UNG_LACPL  ;  A5VIJ2, UNG_LACRD  ;  B2G626, UNG_LACRJ  ;
DR   Q38VY5, UNG_LACSS  ;  B1MXY4, UNG_LEUCK  ;  Q03W63, UNG_LEUMM  ;
DR   B1I012, UNG_LYSSC  ;  B9E8N2, UNG_MACCJ  ;  Q65VN0, UNG_MANSM  ;
DR   P97931, UNG_MOUSE  ;  A0QJA9, UNG_MYCA1  ;  B1MDP0, UNG_MYCA9  ;
DR   P67072, UNG_MYCBO  ;  A1KMX0, UNG_MYCBP  ;  C1AG91, UNG_MYCBT  ;
DR   P47343, UNG_MYCGE  ;  A4TE31, UNG_MYCGI  ;  Q4A8N4, UNG_MYCH7  ;
DR   B8ZS02, UNG_MYCLB  ;  Q9CBS3, UNG_MYCLE  ;  B2HIJ2, UNG_MYCMM  ;
DR   Q73VJ7, UNG_MYCPA  ;  P75536, UNG_MYCPN  ;  Q98PV4, UNG_MYCPU  ;
DR   A0QV01, UNG_MYCS2  ;  A3PXS4, UNG_MYCSJ  ;  A1UEC0, UNG_MYCSK  ;
DR   Q1BAP2, UNG_MYCSS  ;  A5U6Y7, UNG_MYCTA  ;  P67071, UNG_MYCTU  ;
DR   A0PQ07, UNG_MYCUA  ;  A1T717, UNG_MYCVP  ;  Q5F8I7, UNG_NEIG1  ;
DR   B4RLL6, UNG_NEIG2  ;  A9LZA2, UNG_NEIM0  ;  Q9JUC4, UNG_NEIMA  ;
DR   Q9JZA1, UNG_NEIMB  ;  A1KU26, UNG_NEIMF  ;  Q5YRZ2, UNG_NOCFA  ;
DR   A1SNW4, UNG_NOCSJ  ;  Q8EPH6, UNG_OCEIH  ;  P57807, UNG_PASMU  ;
DR   C6DC11, UNG_PECCP  ;  Q03GV8, UNG_PEDPA  ;  Q7N1U8, UNG_PHOLL  ;
DR   B2RHL6, UNG_PORG3  ;  Q7MXF6, UNG_PORGI  ;  B4F058, UNG_PROMH  ;
DR   Q48ET5, UNG_PSE14  ;  A6VAM7, UNG_PSEA7  ;  B7UYZ2, UNG_PSEA8  ;
DR   Q02HQ1, UNG_PSEAB  ;  Q9I5H9, UNG_PSEAE  ;  P29950, UNG_PSEDE  ;
DR   Q1I5T6, UNG_PSEE4  ;  Q4KGS0, UNG_PSEF5  ;  C3KDS6, UNG_PSEFS  ;
DR   Q3IG47, UNG_PSEHT  ;  A5W8H2, UNG_PSEP1  ;  Q3KGL4, UNG_PSEPF  ;
DR   B0KV50, UNG_PSEPG  ;  Q88N05, UNG_PSEPK  ;  B1J4J3, UNG_PSEPW  ;
DR   Q87XE2, UNG_PSESM  ;  Q4ZPC2, UNG_PSEU2  ;  Q6UDG6, UNG_PSHV1  ;
DR   A1SUE5, UNG_PSYIN  ;  B2UDL1, UNG_RALPJ  ;  Q8XVE4, UNG_RALSO  ;
DR   P32941, UNG_RFVKA  ;  Q92LU5, UNG_RHIME  ;  Q21SE9, UNG_RHOFD  ;
DR   B5F228, UNG_SALA4  ;  A9MGV9, UNG_SALAR  ;  Q57L54, UNG_SALCH  ;
DR   B5FRD9, UNG_SALDC  ;  B5QTW1, UNG_SALEP  ;  B5RD62, UNG_SALG2  ;
DR   B4TE28, UNG_SALHS  ;  B4T290, UNG_SALNS  ;  Q5PLH8, UNG_SALPA  ;
DR   A9N0W3, UNG_SALPB  ;  C0PVZ2, UNG_SALPC  ;  B5BAR7, UNG_SALPK  ;
DR   B4TS29, UNG_SALSV  ;  P67074, UNG_SALTI  ;  P67073, UNG_SALTY  ;
DR   O74834, UNG_SCHPO  ;  A8GI39, UNG_SERP5  ;  Q07YI6, UNG_SHEFN  ;
DR   Q8EB78, UNG_SHEON  ;  B2TYK1, UNG_SHIB3  ;  Q31XQ4, UNG_SHIBS  ;
DR   Q32CT9, UNG_SHIDS  ;  Q0T1S6, UNG_SHIF8  ;  Q3YYT5, UNG_SHISS  ;
DR   Q01019, UNG_SHV21  ;  Q1GHJ4, UNG_SILST  ;  A6UDC0, UNG_SINMW  ;
DR   Q2NS03, UNG_SODGM  ;  A7WZ22, UNG_STAA1  ;  A6TZ58, UNG_STAA2  ;
DR   Q2FJ62, UNG_STAA3  ;  Q2G0J7, UNG_STAA8  ;  A5IQD5, UNG_STAA9  ;
DR   Q2YS83, UNG_STAAB  ;  Q5HI95, UNG_STAAC  ;  A6QEN4, UNG_STAAE  ;
DR   P67075, UNG_STAAM  ;  P67076, UNG_STAAN  ;  Q6GJ88, UNG_STAAR  ;
DR   Q6GBQ6, UNG_STAAS  ;  A8YZS8, UNG_STAAT  ;  P67077, UNG_STAAW  ;
DR   B9DKT3, UNG_STACT  ;  Q5HRG5, UNG_STAEQ  ;  Q8CQ65, UNG_STAES  ;
DR   Q4L3Q7, UNG_STAHJ  ;  Q49VD1, UNG_STAS1  ;  P0A4P5, UNG_STRA1  ;
DR   P0A4P3, UNG_STRA3  ;  P0A4P4, UNG_STRA5  ;  C0M7J9, UNG_STRE4  ;
DR   B4U3D4, UNG_STREM  ;  A8AXM4, UNG_STRGC  ;  Q8DTV8, UNG_STRMU  ;
DR   Q9A072, UNG_STRP1  ;  Q04KE2, UNG_STRP2  ;  P0DG74, UNG_STRP3  ;
DR   B5E4R3, UNG_STRP4  ;  Q5XCK3, UNG_STRP6  ;  Q8P1B6, UNG_STRP8  ;
DR   Q1JC76, UNG_STRPB  ;  Q1JM60, UNG_STRPC  ;  Q1JHA5, UNG_STRPD  ;
DR   Q1J724, UNG_STRPF  ;  A2RF00, UNG_STRPG  ;  B1IBW9, UNG_STRPI  ;
DR   B8ZQ48, UNG_STRPJ  ;  Q48U05, UNG_STRPM  ;  P23379, UNG_STRPN  ;
DR   P0DG75, UNG_STRPQ  ;  B5XL20, UNG_STRPZ  ;  Q8DPQ4, UNG_STRR6  ;
DR   A4W1D5, UNG_STRS2  ;  C0ME57, UNG_STRS7  ;  A3CN85, UNG_STRSV  ;
DR   A4VV30, UNG_STRSY  ;  Q03KM6, UNG_STRTD  ;  B9DSB9, UNG_STRU0  ;
DR   C1CED4, UNG_STRZJ  ;  C1CKR8, UNG_STRZP  ;  C1CRP5, UNG_STRZT  ;
DR   P52506, UNG_SUHVF  ;  P52507, UNG_SUHVK  ;  Q30Q92, UNG_SULDN  ;
DR   Q47Q90, UNG_THEFY  ;  C4LC44, UNG_TOLAT  ;  P67079, UNG_TROW8  ;
DR   P67078, UNG_TROWT  ;  B1AJI8, UNG_UREP2  ;  Q9PPU2, UNG_UREPA  ;
DR   B5ZC55, UNG_UREU1  ;  Q91UM2, UNG_VACCA  ;  P20536, UNG_VACCC  ;
DR   P04303, UNG_VACCW  ;  P32988, UNG_VAR67  ;  A5F5R5, UNG_VIBC3  ;
DR   Q9KPK8, UNG_VIBCH  ;  C3LQD1, UNG_VIBCM  ;  Q5E2Y8, UNG_VIBF1  ;
DR   B5FAJ7, UNG_VIBFM  ;  A7MS85, UNG_VIBHB  ;  Q87SC4, UNG_VIBPA  ;
DR   Q8DEP7, UNG_VIBVU  ;  Q7MNR0, UNG_VIBVY  ;  P09307, UNG_VZVD   ;
DR   Q9J3N2, UNG_VZVO   ;  Q7MA00, UNG_WOLSU  ;  Q8PFZ6, UNG_XANAC  ;
DR   Q3BNI2, UNG_XANC5  ;  Q4UPY9, UNG_XANC8  ;  B0RWT2, UNG_XANCB  ;
DR   Q8P4D7, UNG_XANCP  ;  Q2NY21, UNG_XANOM  ;  B2SJF5, UNG_XANOP  ;
DR   Q5GUS2, UNG_XANOR  ;  B2IAB2, UNG_XYLF2  ;  Q9PA28, UNG_XYLFA  ;
DR   B0U620, UNG_XYLFM  ;  Q879Z0, UNG_XYLFT  ;  P12887, UNG_YEAST  ;
DR   A1JKI8, UNG_YERE8  ;  A7FFS4, UNG_YERP3  ;  Q1C570, UNG_YERPA  ;
DR   B2KA63, UNG_YERPB  ;  Q8ZD85, UNG_YERPE  ;  A9R3Y6, UNG_YERPG  ;
DR   Q1CKF8, UNG_YERPN  ;  A4TKZ2, UNG_YERPP  ;  Q667T7, UNG_YERPS  ;
DR   B1JRB1, UNG_YERPY  ;
//
ID   3.2.2.28
DE   Double-stranded uracil-DNA glycosylase.
AN   DsUDG.
CA   Specifically hydrolyzes mismatched double-stranded DNA and
CA   polynucleotides, releasing free uracil.
CC   -!- No activity on DNA containing a T/G mispair or single-stranded DNA
CC       containing either a site-specific uracil or 3,N(4)-ethenocytosine
CC       residue, significant role for double-stranded uracil-DNA glycosylase
CC       in mutation avoidance in non-dividing Escherichia coli.
CC   -!- Uracil-DNA glycosylases are widespread enzymes that are found in all
CC       living organisms.
CC   -!- Uracil-DNA glycosylase (EC 3.2.2.27) and double-stranded uracil-DNA
CC       glycosylase (EC 3.2.2.28) form a central part of the DNA-repair
CC       machinery since they initiate the DNA base-excision repair pathway by
CC       hydrolyzing the N-glycosidic bond between uracil and the deoxyribose
CC       sugar thereby catalyzing the removal of mis-incorporated uracil from
CC       DNA.
DR   A8APW0, MUG_CITK8  ;  A7ZRV0, MUG_ECO24  ;  B7MB04, MUG_ECO45  ;
DR   B7LH04, MUG_ECO55  ;  Q8XAN4, MUG_ECO57  ;  B5YRA8, MUG_ECO5E  ;
DR   B7NJT2, MUG_ECO7I  ;  B7N0L8, MUG_ECO81  ;  B7LZL8, MUG_ECO8A  ;
DR   C4ZQY5, MUG_ECOBW  ;  B1XG73, MUG_ECODH  ;  A8A4M5, MUG_ECOHS  ;
DR   A1AFY9, MUG_ECOK1  ;  Q0TD38, MUG_ECOL5  ;  P0A9H2, MUG_ECOL6  ;
DR   B1IRP8, MUG_ECOLC  ;  P0A9H1, MUG_ECOLI  ;  B7ND57, MUG_ECOLU  ;
DR   B6I441, MUG_ECOSE  ;  B1LF61, MUG_ECOSM  ;  Q1R6R1, MUG_ECOUT  ;
DR   A4WEK3, MUG_ENT38  ;  A7MJU3, MUG_ENTS8  ;  Q6D9D7, MUG_ERWCT  ;
DR   B7LQE3, MUG_ESCF3  ;  B5XU18, MUG_KLEP3  ;  A6TE50, MUG_KLEP7  ;
DR   C6DKG5, MUG_PECCP  ;  B5F6A8, MUG_SALA4  ;  A9MPV1, MUG_SALAR  ;
DR   Q57JP7, MUG_SALCH  ;  B5FHU7, MUG_SALDC  ;  B5QZ48, MUG_SALEP  ;
DR   B5REH0, MUG_SALG2  ;  B4TI63, MUG_SALHS  ;  B4T682, MUG_SALNS  ;
DR   Q5PKX5, MUG_SALPA  ;  A9N5Z1, MUG_SALPB  ;  C0PYY5, MUG_SALPC  ;
DR   B5BG24, MUG_SALPK  ;  B4TVU6, MUG_SALSV  ;  Q8XFG2, MUG_SALTI  ;
DR   Q7CPR7, MUG_SALTY  ;  P43343, MUG_SERMA  ;  A8GJV5, MUG_SERP5  ;
DR   B2U1S3, MUG_SHIB3  ;  Q31WW5, MUG_SHIBS  ;  Q32BP9, MUG_SHIDS  ;
DR   Q0T0J4, MUG_SHIF8  ;  Q3YXH4, MUG_SHISS  ;  O59825, TDG_SCHPO  ;
//
ID   3.2.2.29
DE   Thymine-DNA glycosylase.
AN   Mismatch-specific thymine-DNA glycosylase.
AN   Mismatch-specific thymine-DNA N-glycosylase.
AN   TDG.
AN   Thymine DNA glycosylase.
AN   Uracil/thymine DNA glycosylase.
CA   Hydrolyzes mismatched double-stranded DNA and polynucleotides, releasing
CA   free thymine.
CC   -!- Thymine-DNA glycosylase is part of the DNA-repair machinery.
CC   -!- Thymine removal is fastest when it is from a G/T mismatch with a
CC       5'-flanking C/G pair.
CC   -!- The glycosylase removes uracil from G/U, C/U, and T/U base pairs
CC       faster than it removes thymine from G/T.
DR   Q13569, TDG_HUMAN  ;  P56581, TDG_MOUSE  ;
//
ID   3.2.3.1
DE   Transferred entry: 3.2.1.147.
//
ID   3.3.1.1
DE   Adenosylhomocysteinase.
AN   Adenosylhomocysteine hydrolase.
AN   AdoHcyase.
AN   S-adenosylhomocysteinase.
AN   S-adenosylhomocysteine hydrolase.
AN   S-adenosylhomocysteine synthase.
AN   SAHase.
CA   S-adenosyl-L-homocysteine + H(2)O = L-homocysteine + adenosine.
CF   NAD.
CC   -!- The NAD(+) cofactor appears to bring about a transient oxidation at
CC       C-3' of the 5'-deoxyadenosine residue, thus labilizing the thioether
CC       bond cf. EC 5.5.1.4.
PR   PROSITE; PDOC00603;
DR   O23255, SAHH1_ARATH;  P84533, SAHH1_POPEU;  Q9LK36, SAHH2_ARATH;
DR   P50245, SAHH2_DROME;  O43865, SAHH2_HUMAN;  Q80SW1, SAHH2_MOUSE;
DR   P84532, SAHH2_POPEU;  Q96HN2, SAHH3_HUMAN;  Q68FL4, SAHH3_MOUSE;
DR   Q5R889, SAHH3_PONAB;  P51893, SAHHA_XENLA;  O93477, SAHHB_XENLA;
DR   A1TUG3, SAHH_ACIAC ;  Q6FA43, SAHH_ACIAD ;  B9MD45, SAHH_ACIET ;
DR   A1W3P0, SAHH_ACISJ ;  Q9YEF2, SAHH_AERPE ;  B9JG53, SAHH_AGRRK ;
DR   Q8UJ99, SAHH_AGRT5 ;  O76757, SAHH_ANOGA ;  O67240, SAHH_AQUAE ;
DR   O28279, SAHH_ARCFU ;  Q5P6B7, SAHH_AROAE ;  Q64MT2, SAHH_BACFR ;
DR   Q8A407, SAHH_BACTN ;  Q6G584, SAHH_BARHE ;  Q6G1D6, SAHH_BARQU ;
DR   A9IL83, SAHH_BART1 ;  Q6MNC0, SAHH_BDEBA ;  Q7WQX5, SAHH_BORBR ;
DR   Q7W1Z7, SAHH_BORPA ;  A9IGY5, SAHH_BORPD ;  Q7VUL8, SAHH_BORPE ;
DR   Q3MHL4, SAHH_BOVIN ;  Q89HP6, SAHH_BRAJA ;  A5ENA7, SAHH_BRASB ;
DR   B2S994, SAHH_BRUA1 ;  Q2YQX8, SAHH_BRUA2 ;  Q57AG3, SAHH_BRUAB ;
DR   A9M9T1, SAHH_BRUC2 ;  C0RFY3, SAHH_BRUMB ;  Q8YE49, SAHH_BRUME ;
DR   A5VT52, SAHH_BRUO2 ;  B0CJJ7, SAHH_BRUSI ;  Q8FXZ7, SAHH_BRUSU ;
DR   A3MQW7, SAHH_BURM7 ;  A2S6W2, SAHH_BURM9 ;  Q62G22, SAHH_BURMA ;
DR   A1V8Z2, SAHH_BURMS ;  A3P0L8, SAHH_BURP0 ;  Q3JY79, SAHH_BURP1 ;
DR   A3NER1, SAHH_BURP6 ;  B2JIP4, SAHH_BURP8 ;  B2T6X2, SAHH_BURPP ;
DR   Q63PT2, SAHH_BURPS ;  Q2STU0, SAHH_BURTA ;  Q13T36, SAHH_BURXL ;
DR   P27604, SAHH_CAEEL ;  P83783, SAHH_CANAL ;  P35007, SAHH_CATRO ;
DR   Q9ABH0, SAHH_CAUCR ;  Q3AQC2, SAHH_CHLCH ;  B3EDY3, SAHH_CHLL2 ;
DR   B3QMF5, SAHH_CHLP8 ;  A1BEZ2, SAHH_CHLPD ;  Q8KEG8, SAHH_CHLTE ;
DR   Q7NZF7, SAHH_CHRVO ;  P61456, SAHH_CORDI ;  Q8FRJ4, SAHH_COREF ;
DR   A4QC87, SAHH_CORGB ;  Q8NSC4, SAHH_CORGL ;  B6J6H1, SAHH_COXB1 ;
DR   B6J3R0, SAHH_COXB2 ;  A9KD88, SAHH_COXBN ;  Q83A77, SAHH_COXBU ;
DR   Q0KF25, SAHH_CUPNH ;  Q476T8, SAHH_CUPPJ ;  B2AGG2, SAHH_CUPTR ;
DR   B7K8X6, SAHH_CYAP7 ;  A9C184, SAHH_DELAS ;  C6C1F4, SAHH_DESAD ;
DR   Q30WL8, SAHH_DESDG ;  Q72EH1, SAHH_DESVH ;  B8DR41, SAHH_DESVM ;
DR   A1VFZ7, SAHH_DESVV ;  P10819, SAHH_DICDI ;  Q27580, SAHH_DROME ;
DR   A5FJK3, SAHH_FLAJ1 ;  A6GW32, SAHH_FLAPJ ;  P61617, SAHH_GEOSL ;
DR   Q7NGI6, SAHH_GLOVI ;  Q0BW40, SAHH_GRABC ;  A0M5W6, SAHH_GRAFK ;
DR   Q2SLT4, SAHH_HAHCH ;  A1WXM7, SAHH_HALHL ;  Q9HN50, SAHH_HALSA ;
DR   Q18EV6, SAHH_HALWD ;  A4G975, SAHH_HERAR ;  P23526, SAHH_HUMAN ;
DR   Q0C427, SAHH_HYPNA ;  A6T2Y9, SAHH_JANMA ;  P36889, SAHH_LEIDO ;
DR   Q04NN6, SAHH_LEPBJ ;  Q04WX0, SAHH_LEPBL ;  B1Y647, SAHH_LEPCP ;
DR   Q75FU8, SAHH_LEPIC ;  Q8EXV1, SAHH_LEPIN ;  Q9SP37, SAHH_LUPLU ;
DR   Q4R596, SAHH_MACFA ;  Q0ALW1, SAHH_MARMM ;  P50246, SAHH_MEDSA ;
DR   P93253, SAHH_MESCR ;  Q11CD0, SAHH_MESSB ;  Q8TRA5, SAHH_METAC ;
DR   B7KSJ4, SAHH_METC4 ;  Q60CG8, SAHH_METCA ;  A9VYP7, SAHH_METEP ;
DR   Q58783, SAHH_METJA ;  P58855, SAHH_METKA ;  Q8PUQ4, SAHH_METMA ;
DR   Q6LYR8, SAHH_METMP ;  B8IPU4, SAHH_METNO ;  B1ZLX0, SAHH_METPB ;
DR   A2SL00, SAHH_METPP ;  B0UM37, SAHH_METS4 ;  O27673, SAHH_METTH ;
DR   P50247, SAHH_MOUSE ;  Q7TWW7, SAHH_MYCBO ;  A1KNQ0, SAHH_MYCBP ;
DR   C1AH22, SAHH_MYCBT ;  B8ZQE9, SAHH_MYCLB ;  Q9CCJ4, SAHH_MYCLE ;
DR   B2HEP6, SAHH_MYCMM ;  Q73UK6, SAHH_MYCPA ;  A4ZHR8, SAHH_MYCS2 ;
DR   A3PW97, SAHH_MYCSJ ;  A1UCK8, SAHH_MYCSK ;  Q1BCD6, SAHH_MYCSS ;
DR   A5U7S2, SAHH_MYCTA ;  P60176, SAHH_MYCTU ;  A0PRF5, SAHH_MYCUA ;
DR   Q1CY84, SAHH_MYXXD ;  P68172, SAHH_NICSY ;  Q0AEV8, SAHH_NITEC ;
DR   Q82WL1, SAHH_NITEU ;  Q5YQS7, SAHH_NOCFA ;  Q8YX05, SAHH_NOSS1 ;
DR   Q2G6T1, SAHH_NOVAD ;  A6WX40, SAHH_OCHA4 ;  Q3A392, SAHH_PELCD ;
DR   Q3B532, SAHH_PELLD ;  B4SD43, SAHH_PELPB ;  Q01781, SAHH_PETCR ;
DR   P50249, SAHH_PHASS ;  Q710C4, SAHH_PIG   ;  Q4XZZ5, SAHH_PLACH ;
DR   P50250, SAHH_PLAF7 ;  Q7RKK8, SAHH_PLAYO ;  Q12663, SAHH_PNECA ;
DR   B1XSH8, SAHH_POLNS ;  A4T0E9, SAHH_POLSQ ;  A3PFB5, SAHH_PROM0 ;
DR   A8G7D1, SAHH_PROM2 ;  A2C620, SAHH_PROM3 ;  A9BD69, SAHH_PROM4 ;
DR   Q318B6, SAHH_PROM9 ;  Q7V9P3, SAHH_PROMA ;  Q7V926, SAHH_PROMM ;
DR   Q7UZN3, SAHH_PROMP ;  A4SF77, SAHH_PROVI ;  Q48PB5, SAHH_PSE14 ;
DR   B7V419, SAHH_PSEA8 ;  Q02TY0, SAHH_PSEAB ;  Q9I685, SAHH_PSEAE ;
DR   Q1I3W5, SAHH_PSEE4 ;  Q4K4H7, SAHH_PSEF5 ;  C3K3G6, SAHH_PSEFS ;
DR   A4XPF3, SAHH_PSEMY ;  A5WA09, SAHH_PSEP1 ;  Q3K5D7, SAHH_PSEPF ;
DR   B0KM00, SAHH_PSEPG ;  B1J2Y8, SAHH_PSEPW ;  Q87V73, SAHH_PSESM ;
DR   Q4ZZ92, SAHH_PSEU2 ;  A4VRF7, SAHH_PSEU5 ;  Q9UYK5, SAHH_PYRAB ;
DR   Q8ZTQ7, SAHH_PYRAE ;  P50251, SAHH_PYRFU ;  O58275, SAHH_PYRHO ;
DR   Q5JED2, SAHH_PYRKO ;  Q1LS20, SAHH_RALME ;  B2U774, SAHH_RALPJ ;
DR   Q8Y387, SAHH_RALSO ;  P10760, SAHH_RAT   ;  B3PVW2, SAHH_RHIE6 ;
DR   Q2KE72, SAHH_RHIEC ;  Q1MNC6, SAHH_RHIL3 ;  Q98CM3, SAHH_RHILO ;
DR   B5ZV80, SAHH_RHILW ;  Q92TC1, SAHH_RHIME ;  Q7TTZ5, SAHH_RHOBA ;
DR   P28183, SAHH_RHOCB ;  Q2IZR1, SAHH_RHOP2 ;  Q6N2N5, SAHH_RHOPA ;
DR   Q13AQ5, SAHH_RHOPS ;  B3QJT3, SAHH_RHOPT ;  O50562, SAHH_RHOSH ;
DR   Q9ZNA5, SAHH_ROSDO ;  O13639, SAHH_SCHPO ;  A6UEJ1, SAHH_SINMW ;
DR   Q9SWF5, SAHH_SOLLC ;  Q01VU1, SAHH_SOLUE ;  Q1GWT5, SAHH_SPHAL ;
DR   Q936D6, SAHH_STRAA ;  Q82DC9, SAHH_STRAW ;  Q8GGL7, SAHH_STRAZ ;
DR   Q9KZM1, SAHH_STRCO ;  P26799, SAHH_STRFR ;  B1VUW6, SAHH_STRGG ;
DR   Q4JAZ7, SAHH_SULAC ;  P50252, SAHH_SULSO ;  Q975T0, SAHH_SULTO ;
DR   A5GI30, SAHH_SYNPW ;  Q7U9Y3, SAHH_SYNPX ;  Q0IDX7, SAHH_SYNS3 ;
DR   Q3B0K7, SAHH_SYNS9 ;  Q3ANF4, SAHH_SYNSC ;  P74008, SAHH_SYNY3 ;
DR   Q9HKX4, SAHH_THEAC ;  Q8DGC8, SAHH_THEEB ;  O51933, SAHH_THEMA ;
DR   Q979Z4, SAHH_THEVO ;  P68173, SAHH_TOBAC ;  P51540, SAHH_TRIVA ;
DR   C5CM29, SAHH_VARPS ;  P32112, SAHH_WHEAT ;  Q8PP84, SAHH_XANAC ;
DR   Q3BXC6, SAHH_XANC5 ;  Q4UQZ8, SAHH_XANC8 ;  Q8PCH5, SAHH_XANCP ;
DR   Q2NZE3, SAHH_XANOM ;  B2SPN6, SAHH_XANOP ;  B2I7N4, SAHH_XYLF2 ;
DR   Q9PEJ1, SAHH_XYLFA ;  B0U232, SAHH_XYLFM ;  Q87EI8, SAHH_XYLFT ;
DR   P39954, SAHH_YEAST ;  Q5NR48, SAHH_ZYMMO ;
//
ID   3.3.1.2
DE   Adenosylmethionine hydrolase.
AN   Methylmethionine-sulfonium-salt hydrolase.
AN   S-adenosyl-L-methionine hydrolase.
AN   S-adenosylmethionine cleaving enzyme.
CA   S-adenosyl-L-methionine + H(2)O = L-homoserine + methylthioadenosine.
CC   -!- Also hydrolyzes methylmethionine sulfonium salt to dimethyl sulfide
CC       and homoserine.
DR   P07693, ADOM_BPT3  ;
//
ID   3.3.1.3
DE   Transferred entry: 4.4.1.21.
//
ID   3.3.2.1
DE   Isochorismatase.
AN   2,3 dihydro-2,3 dihydroxybenzoate synthase.
CA   Isochorismate + H(2)O = 2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate.
DR   P45743, DHBB_BACSU ;  P0ADI5, ENTB_ECO57 ;  P0ADI4, ENTB_ECOLI ;
DR   P0ADI6, ENTB_SHIFL ;  Q51518, PHZA_PSECL ;  Q51790, PHZD_PSEFL ;
DR   P74965, VENB_VIBVU ;  A5F3F4, VIBB_VIBC3 ;  P0C6D3, VIBB_VIBCH ;
//
ID   3.3.2.2
DE   Alkenylglycerophosphocholine hydrolase.
CA   1-(1-alkenyl)-sn-glycero-3-phosphocholine + H(2)O = an aldehyde +
CA   sn-glycero-3-phosphocholine.
DR   Q3T0W0, TM86B_BOVIN;  Q8N661, TM86B_HUMAN;  Q497J1, TM86B_MOUSE;
DR   F1RMN2, TM86B_PIG  ;  B0BNF0, TM86B_RAT  ;
//
ID   3.3.2.3
DE   Transferred entry: 3.3.2.9 and 3.3.2.10.
//
ID   3.3.2.4
DE   Trans-epoxysuccinate hydrolase.
AN   Trans-epoxysuccinate hydratase.
CA   Trans-2,3-epoxysuccinate + H(2)O = meso-tartrate.
CC   -!- Acts on both optical isomers of the substrate.
CC   -!- Formerly EC 4.2.1.37.
//
ID   3.3.2.5
DE   Alkenylglycerophosphoethanolamine hydrolase.
CA   1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine + H(2)O = an aldehyde +
CA   sn-glycero-3-phosphoethanolamine.
DR   Q3T0W0, TM86B_BOVIN;  Q8N661, TM86B_HUMAN;  Q497J1, TM86B_MOUSE;
DR   F1RMN2, TM86B_PIG  ;  B0BNF0, TM86B_RAT  ;
//
ID   3.3.2.6
DE   Leukotriene-A(4) hydrolase.
AN   Leukotriene A(4) hydrolase.
AN   Leukotriene-A4 hydrolase.
AN   LTA-4 hydrolase.
CA   (7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate + H(2)O =
CA   (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate.
CF   Zinc.
CC   -!- A bifunctional zinc metalloprotease that displays both epoxide
CC       hydrolase and aminopeptidase activities.
CC   -!- It preferentially cleaves tripeptides at an arginyl bond, with
CC       dipeptides and tetrapeptides being poorer substrates.
CC   -!- It also converts leukotriene A(4) into leukotriene B(4), unlike
CC       EC 3.2.2.10 which converts leukotriene A(4) into 5,6-dihydroxy-
CC       7,9,11,14-eicosatetraenoic acid.
PR   PROSITE; PDOC00129;
DR   A5DME6, LKA41_PICGU;  A3LRX6, LKA41_PICST;  A5DGF3, LKA42_PICGU;
DR   A3LQI7, LKA42_PICST;  A6RCT2, LKHA4_AJECN;  Q75B10, LKHA4_ASHGO;
DR   A1CSI2, LKHA4_ASPCL;  Q4X265, LKHA4_ASPFU;  A2QKF8, LKHA4_ASPNC;
DR   Q2TZ99, LKHA4_ASPOR;  Q0CFY9, LKHA4_ASPTN;  A6SAG8, LKHA4_BOTFB;
DR   Q3SZH7, LKHA4_BOVIN;  Q59NB8, LKHA4_CANAL;  Q6FTM0, LKHA4_CANGA;
DR   P19602, LKHA4_CAVPO;  Q2GY21, LKHA4_CHAGB;  Q6S9C8, LKHA4_CHILA;
DR   Q1DVD1, LKHA4_COCIM;  Q6BW21, LKHA4_DEBHA;  P52922, LKHA4_DICDI;
DR   Q5B0W8, LKHA4_EMENI;  P09960, LKHA4_HUMAN;  Q6CLD3, LKHA4_KLULA;
DR   A5DSS4, LKHA4_LODEL;  A4QUC1, LKHA4_MAGO7;  P24527, LKHA4_MOUSE;
DR   A1DG68, LKHA4_NEOFI;  Q7S785, LKHA4_NEUCR;  Q0U653, LKHA4_PHANO;
DR   P30349, LKHA4_RAT  ;  O94544, LKHA4_SCHPO;  A7EJL9, LKHA4_SCLS1;
DR   A7THG7, LKHA4_VANPO;  Q6C3E5, LKHA4_YARLI;  A6ZS33, LKHA4_YEAS7;
DR   Q10740, LKHA4_YEAST;
//
ID   3.3.2.7
DE   Hepoxilin-epoxide hydrolase.
AN   Hepoxilin A(3) hydrolase.
AN   Hepoxilin epoxide hydrolase.
AN   Hepoxylin hydrolase.
CA   (5Z,9E,14Z)-(8-xi,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate +
CA   H(2)O = (5Z,9E,14Z)-(8-xi,11-xi,12S)-8,11,12-trihydroxyicosa-5,9,14-
CA   trienoate.
CC   -!- Converts hepoxilin A(3) into trioxilin A(3).
CC   -!- Highly specific for the substrate, having only slight activity with
CC       other epoxides such as leukotriene A(4) and styrene oxide.
CC   -!- Probably plays a modulatory role in inflammation, vascular
CC       physiology, systemic glucose metabolism and neurological function.
//
ID   3.3.2.8
DE   Limonene-1,2-epoxide hydrolase.
AN   Limonene oxide hydrolase.
CA   Limonene-1,2-epoxide + H(2)O = limonene-1,2-diol.
CC   -!- Involved in the monoterpene degradation pathway of the actinomycete
CC       Rhodococcus erythropolis.
CC   -!- The enzyme hydrolyzes several alicyclic and 1-methyl-substituted
CC       epoxides, such as 1-methylcyclohexene oxide, indene oxide and
CC       cyclohexene oxide.
CC   -!- It differs from the previously described epoxide hydrolases
CC       (EC 3.3.2.4, EC 3.3.2.6, EC 3.3.2.7, EC 3.3.2.9 and EC 3.3.2.10) as
CC       it is not inhibited by 2-bromo-4'-nitroacetophenone, diethyl
CC       pyrocarbonate, 4-fluorochalcone oxide or 1,10-phenanthroline.
DR   Q9ZAG3, LIMA_RHOER ;
//
ID   3.3.2.9
DE   Microsomal epoxide hydrolase.
AN   Arene-oxide hydratase.
AN   Aryl epoxide hydrase.
AN   Benzo[a]pyrene-4,5-oxide hydratase.
AN   Cis-epoxide hydrolase.
AN   Epoxide hydrase.
AN   Epoxide hydratase.
AN   MEH.
AN   Microsomal epoxide hydrase.
AN   Microsomal epoxide hydratase.
CA   Cis-stilbene oxide + H(2)O = (+)-(1R,2R)-1,2-diphenylethane-1,2-diol.
CC   -!- Involved in the metabolism of numerous xenobiotics, such as 1,3-
CC       butadiene oxide, styrene oxide and the polycyclic aromatic
CC       hydrocarbon benzo[a]pyrene 4,5-oxide.
CC   -!- In a series of oxiranes with a lipophilic substituent of sufficient
CC       size (styrene oxides), monosubstituted as well as 1,1- and cis-1,2-
CC       disubstituted oxiranes serve as substrates or inhibitors of the
CC       enzyme, while trans-1,2-disubstituted, tri- and tetra-substituted
CC       oxiranes are not substrates.
CC   -!- The reaction involves the formation of an hydroxyalkyl-enzyme
CC       intermediate.
CC   -!- Formerly EC 3.3.2.3, EC 4.2.1.63 and EC 4.2.1.64.
DR   Q8MZR6, HYEP1_CTEFE;  Q8MZR5, HYEP2_CTEFE;  Q6U6J0, HYEP_BOMMO ;
DR   P07099, HYEP_HUMAN ;  Q25489, HYEP_MANSE ;  Q9D379, HYEP_MOUSE ;
DR   P79381, HYEP_PIG   ;  P04068, HYEP_RABIT ;  P07687, HYEP_RAT   ;
//
ID   3.3.2.10
DE   Soluble epoxide hydrolase.
AN   Arene-oxide hydratase.
AN   Aryl epoxide hydrase.
AN   Cytosolic epoxide hydrolase.
AN   Epoxide hydrase.
AN   Epoxide hydratase.
AN   Trans-stilbene oxide hydrolase.
CA   An epoxide + H(2)O = a glycol.
CC   -!- Catalyzes the hydrolysis of trans-substituted epoxides, such as
CC       trans-stilbene oxide, as well as various aliphatic epoxides derived
CC       from fatty-acid metabolism.
CC   -!- It is involved in the metabolism of arachidonic epoxides
CC       (epoxyeicosatrienoic acids; EETs) and linoleic acid epoxides.
CC   -!- The enzyme from mammals is a bifunctional enzyme: the C-terminal
CC       domain exhibits epoxide-hydrolase activity and the N-terminal domain
CC       has the activity of EC 3.1.3.76.
CC   -!- Like EC 3.3.2.9, it is probable that the reaction involves the
CC       formation of an hydroxyalkyl-enzyme intermediate.
CC   -!- The enzyme can also use leukotriene A(4), the substrate of
CC       EC 3.3.2.6, but it forms 5,6-dihydroxy-7,9,11,14-eicosatetraenoic
CC       acid rather than leukotriene B(4) as the product.
CC   -!- Formerly EC 3.3.2.3, EC 4.2.1.63 and EC 4.2.1.64.
DR   P80048, HYEP_PSEU1 ;  Q06816, HYEP_STIAD ;  O52866, HYES_CORS2 ;
DR   P34913, HYES_HUMAN ;  P34914, HYES_MOUSE ;  Q6Q2C2, HYES_PIG   ;
DR   P80299, HYES_RAT   ;
//
ID   3.3.2.11
DE   Cholesterol-5,6-oxide hydrolase.
AN   ChEH.
AN   Cholesterol-epoxide hydrolase.
CA   (1) 5,6-alpha-epoxy-5-alpha-cholestan-3-beta-ol + H(2)O = cholestane-3-
CA   beta,5-alpha,6-beta-triol.
CA   (2) 5,6-beta-epoxy-5-beta-cholestan-3-beta-ol + H(2)O = cholestane-3-
CA   beta,5-alpha,6-beta-triol.
CC   -!- The enzyme appears to work equally well with both diastereoisomers of
CC       cholesterol 5,6-epoxide.
CC   -!- The product is a competitive inhibitor of the reaction.
//
ID   3.4.1.1
DE   Transferred entry: 3.4.11.1.
//
ID   3.4.1.2
DE   Transferred entry: 3.4.11.2.
//
ID   3.4.1.3
DE   Transferred entry: 3.4.11.4.
//
ID   3.4.1.4
DE   Transferred entry: 3.4.11.5.
//
ID   3.4.2.1
DE   Transferred entry: 3.4.17.1.
//
ID   3.4.2.2
DE   Transferred entry: 3.4.17.2.
//
ID   3.4.2.3
DE   Transferred entry: 3.4.17.4.
//
ID   3.4.3.1
DE   Transferred entry: 3.4.13.18 and 3.4.13.19.
//
ID   3.4.3.2
DE   Transferred entry: 3.4.13.18 and 3.4.13.19.
//
ID   3.4.3.3
DE   Transferred entry: 3.4.13.3.
//
ID   3.4.3.4
DE   Transferred entry: 3.4.13.5.
//
ID   3.4.3.5
DE   Transferred entry: 3.4.11.2.
//
ID   3.4.3.6
DE   Transferred entry: 3.4.13.18 and 3.4.13.19.
//
ID   3.4.3.7
DE   Transferred entry: 3.4.13.9.
//
ID   3.4.4.1
DE   Transferred entry: 3.4.23.1.
//
ID   3.4.4.2
DE   Transferred entry: 3.4.23.2.
//
ID   3.4.4.3
DE   Transferred entry: 3.4.23.4.
//
ID   3.4.4.4
DE   Transferred entry: 3.4.21.4.
//
ID   3.4.4.5
DE   Transferred entry: 3.4.21.1.
//
ID   3.4.4.6
DE   Transferred entry: 3.4.21.1.
//
ID   3.4.4.7
DE   Transferred entry: 3.4.21.36 and 3.4.21.37.
//
ID   3.4.4.8
DE   Transferred entry: 3.4.21.9.
//
ID   3.4.4.9
DE   Transferred entry: 3.4.14.1.
//
ID   3.4.4.10
DE   Transferred entry: 3.4.22.2.
//
ID   3.4.4.11
DE   Transferred entry: 3.4.22.6.
//
ID   3.4.4.12
DE   Transferred entry: 3.4.22.3.
//
ID   3.4.4.13
DE   Transferred entry: 3.4.21.5.
//
ID   3.4.4.14
DE   Transferred entry: 3.4.21.7.
//
ID   3.4.4.15
DE   Transferred entry: 3.4.23.15.
//
ID   3.4.4.16
DE   Transferred entry: 3.4.21.62, 3.4.21.63, 3.4.21.64, 3.4.21.65, 3.4.21.66
DE   and 3.4.21.67.
//
ID   3.4.4.17
DE   Transferred entry: 3.4.21.103, 3.4.23.20, 3.4.23.21, 3.4.23.22,
DE   3.4.23.23, 3.4.23.24, 3.4.23.25, 3.4.23.26, 3.4.23.28, 3.4.23.29 and
DE   3.4.23.30.
//
ID   3.4.4.18
DE   Transferred entry: 3.4.22.10.
//
ID   3.4.4.19
DE   Transferred entry: 3.4.24.3.
//
ID   3.4.4.20
DE   Transferred entry: 3.4.22.8.
//
ID   3.4.4.21
DE   Transferred entry: 3.4.21.34.
//
ID   3.4.4.22
DE   Transferred entry: 3.4.23.3.
//
ID   3.4.4.23
DE   Transferred entry: 3.4.23.5.
//
ID   3.4.4.24
DE   Transferred entry: 3.4.22.32 and 3.4.22.33.
//
ID   3.4.4.25
DE   Deleted entry.
//
ID   3.4.11.1
DE   Leucyl aminopeptidase.
AN   Cytosol aminopeptidase.
AN   Leucine aminopeptidase.
AN   Peptidase S.
CA   Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is
CA   preferably Leu, but may be other amino acids including Pro although not
CA   Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are
CA   also readily hydrolyzed, but rates on arylamides are exceedingly low.
CF   Zinc.
CC   -!- Is activated by heavy metal ions.
CC   -!- Belongs to peptidase family M17.
CC   -!- Formerly EC 3.4.1.1.
PR   PROSITE; PDOC00548;
DR   Q8EI85, AMPA1_SHEON;  Q8EH62, AMPA2_SHEON;  B0CCF6, AMPA_ACAM1 ;
DR   Q6FFD8, AMPA_ACIAD ;  B7H1P9, AMPA_ACIB3 ;  B7I309, AMPA_ACIB5 ;
DR   B2I1U0, AMPA_ACIBC ;  Q1IPU7, AMPA_ACIBL ;  B0VMG3, AMPA_ACIBS ;
DR   A3M1A8, AMPA_ACIBT ;  B0VDC8, AMPA_ACIBY ;  C1F4B7, AMPA_ACIC5 ;
DR   B9MJ44, AMPA_ACIET ;  B7J5I9, AMPA_ACIF2 ;  B5EKZ2, AMPA_ACIF5 ;
DR   A1W776, AMPA_ACISJ ;  A3N1A7, AMPA_ACTP2 ;  B3GXY6, AMPA_ACTP7 ;
DR   B0BQ37, AMPA_ACTPJ ;  A6VMX3, AMPA_ACTSZ ;  A0KPF3, AMPA_AERHH ;
DR   Q9Y935, AMPA_AERPE ;  A4SSA7, AMPA_AERS4 ;  B9JCD8, AMPA_AGRRK ;
DR   Q8UGC8, AMPA_AGRT5 ;  B9JUW1, AMPA_AGRVS ;  Q0VSA5, AMPA_ALCBS ;
DR   Q0AB75, AMPA_ALHEH ;  B6EMT2, AMPA_ALISL ;  A6TWW9, AMPA_ALKMQ ;
DR   A8ML24, AMPA_ALKOO ;  Q3M9J6, AMPA_ANAVT ;  O67868, AMPA_AQUAE ;
DR   Q5NXM1, AMPA_AROAE ;  A1K9L5, AMPA_AZOSB ;  C1DPG2, AMPA_AZOVD ;
DR   A7Z8B5, AMPA_BACA2 ;  C3PDF7, AMPA_BACAA ;  C3LC57, AMPA_BACAC ;
DR   A0RKB5, AMPA_BACAH ;  Q81XS5, AMPA_BACAN ;  B7JDH9, AMPA_BACC0 ;
DR   Q72YG1, AMPA_BACC1 ;  B7IMU0, AMPA_BACC2 ;  C1EX85, AMPA_BACC3 ;
DR   B7HBG1, AMPA_BACC4 ;  B7HUR5, AMPA_BACC7 ;  A7GUC8, AMPA_BACCN ;
DR   B9J3C5, AMPA_BACCQ ;  Q816E3, AMPA_BACCR ;  Q632E1, AMPA_BACCZ ;
DR   Q6HBY2, AMPA_BACHK ;  Q65FE6, AMPA_BACLD ;  A8FH04, AMPA_BACP2 ;
DR   O32106, AMPA_BACSU ;  A9VMY8, AMPA_BACWK ;  Q1LTH8, AMPA_BAUCH ;
DR   Q6MH10, AMPA_BDEBA ;  Q7VQT0, AMPA_BLOFL ;  Q2KWX0, AMPA_BORA1 ;
DR   Q7WD42, AMPA_BORBR ;  Q7W5K6, AMPA_BORPA ;  A9IIK3, AMPA_BORPD ;
DR   Q7VW48, AMPA_BORPE ;  Q89MT4, AMPA_BRAJA ;  A5EIB4, AMPA_BRASB ;
DR   Q8YG99, AMPA_BRUME ;  A5VPM3, AMPA_BRUO2 ;  Q8G1M4, AMPA_BRUSU ;
DR   B8D9F2, AMPA_BUCA5 ;  P57448, AMPA_BUCAI ;  Q8K9I0, AMPA_BUCAP ;
DR   B8D7Q4, AMPA_BUCAT ;  Q89AG2, AMPA_BUCBP ;  B1YUW5, AMPA_BURA4 ;
DR   Q1BUE7, AMPA_BURCA ;  B1JWV2, AMPA_BURCC ;  A0K9N9, AMPA_BURCH ;
DR   B4E8G9, AMPA_BURCJ ;  Q0BCQ2, AMPA_BURCM ;  A9AHG9, AMPA_BURM1 ;
DR   A3MLR1, AMPA_BURM7 ;  A2SAC2, AMPA_BURM9 ;  Q62LH2, AMPA_BURMA ;
DR   A1V5Z5, AMPA_BURMS ;  A3NSI1, AMPA_BURP0 ;  Q3JV16, AMPA_BURP1 ;
DR   A3N6U4, AMPA_BURP6 ;  B2JET5, AMPA_BURP8 ;  B2T146, AMPA_BURPP ;
DR   Q63WC3, AMPA_BURPS ;  Q39DS5, AMPA_BURS3 ;  Q2T0C0, AMPA_BURTA ;
DR   A4JGZ2, AMPA_BURVG ;  Q143Y9, AMPA_BURXL ;  Q9PP04, AMPA_CAMJE ;
DR   Q9A7M9, AMPA_CAUCR ;  A0RUA5, AMPA_CENSY ;  Q5L681, AMPA_CHLAB ;
DR   Q823J9, AMPA_CHLCV ;  Q254B9, AMPA_CHLFF ;  B3ED46, AMPA_CHLL2 ;
DR   P38019, AMPA_CHLMU ;  B3QNM5, AMPA_CHLP8 ;  A1BGN2, AMPA_CHLPD ;
DR   Q9Z8F8, AMPA_CHLPN ;  B0B9F3, AMPA_CHLT2 ;  B3QVE8, AMPA_CHLT3 ;
DR   Q3KMX6, AMPA_CHLTA ;  B0BB32, AMPA_CHLTB ;  Q8KD74, AMPA_CHLTE ;
DR   O84049, AMPA_CHLTR ;  Q1QTE5, AMPA_CHRSD ;  Q7NTY9, AMPA_CHRVO ;
DR   A8AMA5, AMPA_CITK8 ;  A5CRI6, AMPA_CLAM3 ;  Q8XHI3, AMPA_CLOPE ;
DR   Q0SQ50, AMPA_CLOPS ;  Q893F8, AMPA_CLOTE ;  Q488M4, AMPA_COLP3 ;
DR   Q6NG90, AMPA_CORDI ;  Q8FNP8, AMPA_COREF ;  Q8NNJ4, AMPA_CORGL ;
DR   Q0K7F5, AMPA_CUPNH ;  Q46XT9, AMPA_CUPPJ ;  B3R663, AMPA_CUPTR ;
DR   B1WR01, AMPA_CYAA5 ;  B8HTK3, AMPA_CYAP4 ;  B7KCB0, AMPA_CYAP7 ;
DR   B7K4A4, AMPA_CYAP8 ;  Q47BG9, AMPA_DECAR ;  C0QC86, AMPA_DESAH ;
DR   B8J457, AMPA_DESDA ;  Q315M7, AMPA_DESDG ;  Q6AJZ3, AMPA_DESPS ;
DR   Q72F03, AMPA_DESVH ;  A8LI79, AMPA_DINSH ;  A7ZVE0, AMPA_ECO24 ;
DR   B7UQR7, AMPA_ECO27 ;  B7MLR5, AMPA_ECO45 ;  B7LCX0, AMPA_ECO55 ;
DR   P68768, AMPA_ECO57 ;  B5Z3L7, AMPA_ECO5E ;  B7NUH4, AMPA_ECO7I ;
DR   B7MSZ3, AMPA_ECO81 ;  B7M9L9, AMPA_ECO8A ;  C4ZRD1, AMPA_ECOBW ;
DR   B1XEN9, AMPA_ECODH ;  A8A816, AMPA_ECOHS ;  A1AJG3, AMPA_ECOK1 ;
DR   Q0T9D1, AMPA_ECOL5 ;  P68766, AMPA_ECOL6 ;  B1ISB1, AMPA_ECOLC ;
DR   P68767, AMPA_ECOLI ;  B7NGJ2, AMPA_ECOLU ;  B6I2H3, AMPA_ECOSE ;
DR   B1LRE5, AMPA_ECOSM ;  Q1R2Z4, AMPA_ECOUT ;  C5BBY4, AMPA_EDWI9 ;
DR   Q5FFZ5, AMPA_EHRRG ;  Q5HAP2, AMPA_EHRRW ;  A4WF25, AMPA_ENT38 ;
DR   Q6DA52, AMPA_ERWCT ;  B2VL42, AMPA_ERWT9 ;  B7LMT2, AMPA_ESCF3 ;
DR   B1YKV4, AMPA_EXIS2 ;  Q8RHT8, AMPA_FUSNN ;  Q74GB4, AMPA_GEOSL ;
DR   C6E543, AMPA_GEOSM ;  C5D720, AMPA_GEOSW ;  A4ISE0, AMPA_GEOTN ;
DR   A5G9C7, AMPA_GEOUR ;  Q7NHC6, AMPA_GLOVI ;  Q5FU70, AMPA_GLUOX ;
DR   Q7VNH9, AMPA_HAEDU ;  Q4QJN7, AMPA_HAEI8 ;  A5UBH1, AMPA_HAEIE ;
DR   A5UFE2, AMPA_HAEIG ;  P45334, AMPA_HAEIN ;  B8F6N9, AMPA_HAEPS ;
DR   Q0I236, AMPA_HAES1 ;  B0UVX4, AMPA_HAES2 ;  Q2SKR0, AMPA_HAHCH ;
DR   A1WUV1, AMPA_HALHL ;  C4K346, AMPA_HAMD5 ;  Q17W06, AMPA_HELAH ;
DR   Q7VGF0, AMPA_HELHP ;  B6JLF2, AMPA_HELP2 ;  B5Z6U1, AMPA_HELPG ;
DR   Q1CTV6, AMPA_HELPH ;  Q9ZLR1, AMPA_HELPJ ;  B2UTQ8, AMPA_HELPS ;
DR   O25294, AMPA_HELPY ;  A4G7P5, AMPA_HERAR ;  Q5QY05, AMPA_IDILO ;
DR   A6T0V4, AMPA_JANMA ;  B5Y2T8, AMPA_KLEP3 ;  A6THI2, AMPA_KLEP7 ;
DR   Q5X1Q9, AMPA_LEGPA ;  A5IAU5, AMPA_LEGPC ;  Q5WTG8, AMPA_LEGPL ;
DR   Q6AFG2, AMPA_LEIXX ;  Q72UC6, AMPA_LEPIC ;  Q8F0Q1, AMPA_LEPIN ;
DR   Q65SA3, AMPA_MANSM ;  Q11HH5, AMPA_MESSB ;  B7KYK4, AMPA_METC4 ;
DR   Q606B9, AMPA_METCA ;  A9VXD6, AMPA_METEP ;  Q1H4U4, AMPA_METFK ;
DR   B1ZAK8, AMPA_METPB ;  A2SH61, AMPA_METPP ;  B1LVC3, AMPA_METRJ ;
DR   B0JL23, AMPA_MICAN ;  C5CCM4, AMPA_MICLC ;  Q7VEN5, AMPA_MYCBO ;
DR   A1KKQ5, AMPA_MYCBP ;  C1AQC8, AMPA_MYCBT ;  P47631, AMPA_MYCGE ;
DR   O32956, AMPA_MYCLE ;  B2HGY2, AMPA_MYCMM ;  Q73YK2, AMPA_MYCPA ;
DR   P75206, AMPA_MYCPN ;  P47707, AMPA_MYCSA ;  A3Q1S2, AMPA_MYCSJ ;
DR   A1UIA8, AMPA_MYCSK ;  Q1B6R7, AMPA_MYCSS ;  A5U4P1, AMPA_MYCTA ;
DR   Q10401, AMPA_MYCTU ;  A0PTP9, AMPA_MYCUA ;  Q9JTI8, AMPA_NEIMA ;
DR   Q0AIF5, AMPA_NITEC ;  Q82X54, AMPA_NITEU ;  Q1QKW6, AMPA_NITHX ;
DR   Q2YB18, AMPA_NITMU ;  Q3JEC8, AMPA_NITOC ;  Q3SS04, AMPA_NITWN ;
DR   Q5YZ53, AMPA_NOCFA ;  B2J3G8, AMPA_NOSP7 ;  Q8Z064, AMPA_NOSS1 ;
DR   A6X259, AMPA_OCHA4 ;  B6JGL8, AMPA_OLICO ;  Q6MC72, AMPA_PARUW ;
DR   P57823, AMPA_PASMU ;  C6DJN2, AMPA_PECCP ;  Q3A831, AMPA_PELCD ;
DR   Q3B4B5, AMPA_PELLD ;  C0QSL9, AMPA_PERMH ;  Q7MZ27, AMPA_PHOLL ;
DR   Q6LUW0, AMPA_PHOPR ;  B1V932, AMPA_PHYAS ;  B3R0N4, AMPA_PHYMT ;
DR   A1VP99, AMPA_POLNA ;  Q12AW5, AMPA_POLSJ ;  Q6A9W5, AMPA_PROAC ;
DR   A3PEG6, AMPA_PROM0 ;  A8G6E3, AMPA_PROM2 ;  A9BBV5, AMPA_PROM4 ;
DR   Q319F5, AMPA_PROM9 ;  Q7VAP4, AMPA_PROMA ;  B4F2N1, AMPA_PROMH ;
DR   Q7V5X8, AMPA_PROMM ;  Q7V0D4, AMPA_PROMP ;  A2BSQ4, AMPA_PROMS ;
DR   Q15PX4, AMPA_PSEA6 ;  A6V0T2, AMPA_PSEA7 ;  B7UVT6, AMPA_PSEA8 ;
DR   Q02RY8, AMPA_PSEAB ;  O68822, AMPA_PSEAE ;  Q1I5F9, AMPA_PSEE4 ;
DR   C3K6G5, AMPA_PSEFS ;  A5VZ69, AMPA_PSEP1 ;  Q3KHM4, AMPA_PSEPF ;
DR   B0KQK8, AMPA_PSEPG ;  Q88P73, AMPA_PSEPK ;  O86436, AMPA_PSEPU ;
DR   B1JBA9, AMPA_PSEPW ;  Q887M0, AMPA_PSESM ;  Q4ZXH7, AMPA_PSEU2 ;
DR   A4VNZ7, AMPA_PSEU5 ;  A1SRZ1, AMPA_PSYIN ;  Q1LJJ6, AMPA_RALME ;
DR   B2UAK8, AMPA_RALPJ ;  Q8XWQ8, AMPA_RALSO ;  B3PUV3, AMPA_RHIE6 ;
DR   Q2KA77, AMPA_RHIEC ;  Q1MIZ4, AMPA_RHIL3 ;  Q984S1, AMPA_RHILO ;
DR   B5ZWY7, AMPA_RHILW ;  Q92QY7, AMPA_RHIME ;  C3M9C8, AMPA_RHISN ;
DR   Q7UJ62, AMPA_RHOBA ;  C1A138, AMPA_RHOE4 ;  Q21WL3, AMPA_RHOFD ;
DR   C1AUB5, AMPA_RHOOB ;  Q2IX74, AMPA_RHOP2 ;  Q07LG0, AMPA_RHOP5 ;
DR   Q6N5B9, AMPA_RHOPA ;  Q215R8, AMPA_RHOPB ;  Q135P8, AMPA_RHOPS ;
DR   B3Q9R8, AMPA_RHOPT ;  A4WRK9, AMPA_RHOS5 ;  Q0SHL0, AMPA_RHOSR ;
DR   C3PMI0, AMPA_RICAE ;  A8GXC3, AMPA_RICB8 ;  Q1RJN2, AMPA_RICBR ;
DR   A8EXL1, AMPA_RICCK ;  Q92J85, AMPA_RICCN ;  Q4UKD7, AMPA_RICFE ;
DR   A8F0Q0, AMPA_RICM5 ;  P27888, AMPA_RICPR ;  C4K1N6, AMPA_RICPU ;
DR   B0BWB2, AMPA_RICRO ;  A8GQW7, AMPA_RICRS ;  Q68XM6, AMPA_RICTY ;
DR   A7NG41, AMPA_ROSCS ;  Q21KZ5, AMPA_SACD2 ;  B5F465, AMPA_SALA4 ;
DR   A9MET9, AMPA_SALAR ;  Q57GC3, AMPA_SALCH ;  B5FSH0, AMPA_SALDC ;
DR   B5R1K2, AMPA_SALEP ;  B5R9L5, AMPA_SALG2 ;  B4TG58, AMPA_SALHS ;
DR   B4T3M4, AMPA_SALNS ;  Q5PJD4, AMPA_SALPA ;  A9N680, AMPA_SALPB ;
DR   C0Q7D6, AMPA_SALPC ;  B5BKS6, AMPA_SALPK ;  B4TTA0, AMPA_SALSV ;
DR   Q8Z116, AMPA_SALTI ;  Q8ZK29, AMPA_SALTY ;  A8G978, AMPA_SERP5 ;
DR   Q12QW7, AMPA_SHEDO ;  Q086N8, AMPA_SHEFN ;  A3QBG2, AMPA_SHELP ;
DR   B8CU18, AMPA_SHEPW ;  A8FS02, AMPA_SHESH ;  B2TYY4, AMPA_SHIB3 ;
DR   Q31TK2, AMPA_SHIBS ;  Q328S1, AMPA_SHIDS ;  Q0SXK0, AMPA_SHIF8 ;
DR   Q83P64, AMPA_SHIFL ;  Q3YU89, AMPA_SHISS ;  A6U7J2, AMPA_SINMW ;
DR   Q2NR41, AMPA_SODGM ;  Q029J4, AMPA_SOLUE ;  B9DIX2, AMPA_STACT ;
DR   Q82AN2, AMPA_STRAW ;  Q9S2Q7, AMPA_STRCO ;  B1VZN5, AMPA_STRGG ;
DR   B4SJ73, AMPA_STRM5 ;  B2FMS4, AMPA_STRMK ;  B2V6F5, AMPA_SULSY ;
DR   Q67NI4, AMPA_SYMTH ;  O06865, AMPA_SYNE7 ;  A0LK12, AMPA_SYNFM ;
DR   Q2JRU4, AMPA_SYNJA ;  Q2JKL5, AMPA_SYNJB ;  B1XK83, AMPA_SYNP2 ;
DR   Q5N569, AMPA_SYNP6 ;  A5GN62, AMPA_SYNPW ;  Q7U8Q1, AMPA_SYNPX ;
DR   A5GV03, AMPA_SYNR3 ;  Q0I816, AMPA_SYNS3 ;  Q3AZE8, AMPA_SYNS9 ;
DR   Q3AHT4, AMPA_SYNSC ;  P73971, AMPA_SYNY3 ;  C5BMG6, AMPA_TERTT ;
DR   Q8DI46, AMPA_THEEB ;  Q31ET3, AMPA_THICR ;  B8GTX6, AMPA_THISH ;
DR   C4LA51, AMPA_TOLAT ;  Q73QZ3, AMPA_TREDE ;  Q11A96, AMPA_TRIEI ;
DR   Q83I32, AMPA_TROW8 ;  Q83G32, AMPA_TROWT ;  C5CLU5, AMPA_VARPS ;
DR   A1WSK3, AMPA_VEREI ;  A5CXK2, AMPA_VESOH ;  A5F5D8, AMPA_VIBC3 ;
DR   P0C6E1, AMPA_VIBCH ;  C3LR42, AMPA_VIBCM ;  Q5E7T8, AMPA_VIBF1 ;
DR   B5F9Q6, AMPA_VIBFM ;  A7MSE5, AMPA_VIBHB ;  Q87LG8, AMPA_VIBPA ;
DR   Q8DCE5, AMPA_VIBVU ;  Q7MHG4, AMPA_VIBVY ;  Q8D295, AMPA_WIGBR ;
DR   Q73IU2, AMPA_WOLPM ;  Q7M8W6, AMPA_WOLSU ;  Q8PGR0, AMPA_XANAC ;
DR   Q3BPA1, AMPA_XANC5 ;  Q4UQP6, AMPA_XANC8 ;  B0RVI0, AMPA_XANCB ;
DR   Q8PCR4, AMPA_XANCP ;  Q2P7G2, AMPA_XANOM ;  B2SPE7, AMPA_XANOP ;
DR   Q5H4N2, AMPA_XANOR ;  A7IFB7, AMPA_XANP2 ;  B2I6L3, AMPA_XYLF2 ;
DR   Q9PH08, AMPA_XYLFA ;  B0U1L5, AMPA_XYLFM ;  Q87F32, AMPA_XYLFT ;
DR   A1JJ31, AMPA_YERE8 ;  A7FML9, AMPA_YERP3 ;  Q1C3R8, AMPA_YERPA ;
DR   B2K3E9, AMPA_YERPB ;  Q8ZBH3, AMPA_YERPE ;  A9R5F5, AMPA_YERPG ;
DR   Q1CM01, AMPA_YERPN ;  A4TQP6, AMPA_YERPP ;  Q66F09, AMPA_YERPS ;
DR   B1JLS9, AMPA_YERPY ;  P30184, AMPL1_ARATH;  Q2QSB9, AMPL1_ORYSJ;
DR   Q10712, AMPL1_SOLLC;  Q8RX72, AMPL2_ARATH;  Q6K669, AMPL2_ORYSJ;
DR   Q42876, AMPL2_SOLLC;  Q944P7, AMPL3_ARATH;  P00727, AMPL_BOVIN ;
DR   P34629, AMPL_CAEEL ;  Q5V9F0, AMPL_DICDI ;  Q8SQZ7, AMPL_ENCCU ;
DR   P28838, AMPL_HUMAN ;  P86249, AMPL_MESAU ;  Q9CPY7, AMPL_MOUSE ;
DR   P28839, AMPL_PIG   ;  Q68FS4, AMPL_RAT   ;  P31427, AMPL_SOLTU ;
DR   Q5XGB9, AMPL_XENTR ;  P95928, APE2_SULSO ;
//
ID   3.4.11.2
DE   Membrane alanyl aminopeptidase.
AN   Amino-oligopeptidase.
AN   Aminopeptidase M.
AN   Aminopeptidase N.
AN   Membrane alanine aminopeptidase.
AN   Membrane aminopeptidase I.
AN   Microsomal aminopeptidase.
AN   Particle-bound aminopeptidase.
AN   Peptidase E.
CA   Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or
CA   arylamide. Xaa is preferably Ala, but may be most amino acids including
CA   Pro (slow action). When a terminal hydrophobic residue is followed by a
CA   prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.
CF   Zinc.
CC   -!- Is not activated by heavy metal ions.
CC   -!- Belongs to peptidase family M1.
CC   -!- Formerly EC 3.4.1.2, EC 3.4.3.5 and EC 3.4.13.6.
PR   PROSITE; PDOC00129;
DR   Q9CIQ1, AMPN1_LACLA;  Q48656, AMPN2_LACLA;  Q10736, AMPN_ACEPA ;
DR   P79098, AMPN_BOVIN ;  P79143, AMPN_CANFA ;  P37893, AMPN_CAUCR ;
DR   O57579, AMPN_CHICK ;  P04825, AMPN_ECOLI ;  P79171, AMPN_FELCA ;
DR   Q10737, AMPN_HAECO ;  P45274, AMPN_HAEIN ;  P81731, AMPN_HELAM ;
DR   P15144, AMPN_HUMAN ;  P37896, AMPN_LACDL ;  Q10730, AMPN_LACHE ;
DR   P0C2T8, AMPN_LACLC ;  A2RI32, AMPN_LACLM ;  P91885, AMPN_MANSE ;
DR   P97449, AMPN_MOUSE ;  P15145, AMPN_PIG   ;  P91887, AMPN_PLUXY ;
DR   P15541, AMPN_RABIT ;  P15684, AMPN_RAT   ;  Q11010, AMPN_STRLI ;
//
ID   3.4.11.3
DE   Cystinyl aminopeptidase.
AN   Cystine aminopeptidase.
AN   Cystyl-aminopeptidase.
AN   Oxytocinase.
CA   Release of an N-terminal amino acid, Cys-|-Xaa-, in which the half-
CA   cystine residue is involved in a disulfide loop, notably in oxytocin or
CA   vasopressin. Hydrolysis rates on a range of aminoacyl arylamides exceed
CA   that for the cystinyl derivative, however.
CF   Zinc.
CC   -!- Belongs to peptidase family M1.
DR   Q9UIQ6, LCAP_HUMAN ;  Q8C129, LCAP_MOUSE ;  P97629, LCAP_RAT   ;
//
ID   3.4.11.4
DE   Tripeptide aminopeptidase.
AN   Aminoexotripeptidase.
AN   Aminotripeptidase.
AN   Imidoendopeptidase.
AN   Lymphopeptidase.
AN   Peptidase B.
AN   Tripeptidase.
CA   Release of the N-terminal residue from a tripeptide.
CF   Zinc.
CC   -!- Widely distributed in mammalian tissues.
CC   -!- Belongs to peptidase family M9.
CC   -!- Formerly EC 3.4.1.3.
DR   A0KIP7, PEPT_AERHH ;  A4SPD7, PEPT_AERS4 ;  B6ER23, PEPT_ALISL ;
DR   A8ML45, PEPT_ALKOO ;  A7ZAB2, PEPT_BACA2 ;  C3P5E3, PEPT_BACAA ;
DR   C3L855, PEPT_BACAC ;  A0RHB6, PEPT_BACAH ;  Q81WU4, PEPT_BACAN ;
DR   B7JJ20, PEPT_BACC0 ;  Q732Y5, PEPT_BACC1 ;  B7ITJ6, PEPT_BACC2 ;
DR   C1ENW4, PEPT_BACC3 ;  B7HDL9, PEPT_BACC4 ;  B7HKU6, PEPT_BACC7 ;
DR   A7GR91, PEPT_BACCN ;  B9IV41, PEPT_BACCQ ;  Q81A48, PEPT_BACCR ;
DR   Q636T5, PEPT_BACCZ ;  Q5LFT7, PEPT_BACFN ;  Q64WS4, PEPT_BACFR ;
DR   Q6HF68, PEPT_BACHK ;  Q65D74, PEPT_BACLD ;  A8FIY2, PEPT_BACP2 ;
DR   Q5WK52, PEPT_BACSK ;  P55179, PEPT_BACSU ;  Q89YZ7, PEPT_BACTN ;
DR   A9VR36, PEPT_BACWK ;  C0ZDI3, PEPT_BREBN ;  A8AHU0, PEPT_CITK8 ;
DR   Q97LS8, PEPT_CLOAB ;  A7FPG2, PEPT_CLOB1 ;  C3L049, PEPT_CLOB6 ;
DR   A5HYY2, PEPT_CLOBH ;  C1FSB0, PEPT_CLOBJ ;  B1IEF5, PEPT_CLOBK ;
DR   A7GAK0, PEPT_CLOBL ;  B1KV00, PEPT_CLOBM ;  A0Q3I1, PEPT_CLONN ;
DR   Q0TV42, PEPT_CLOP1 ;  Q8XPD8, PEPT_CLOPE ;  A9KT72, PEPT_CLOPH ;
DR   Q0SWT9, PEPT_CLOPS ;  B8G1J0, PEPT_DESHD ;  Q24VU3, PEPT_DESHY ;
DR   A7ZKR7, PEPT_ECO24 ;  B7UQ36, PEPT_ECO27 ;  B7MJB5, PEPT_ECO45 ;
DR   P65804, PEPT_ECO57 ;  B7MTQ8, PEPT_ECO81 ;  C4ZS67, PEPT_ECOBW ;
DR   B1XA37, PEPT_ECODH ;  A7ZZ82, PEPT_ECOHS ;  A1AA21, PEPT_ECOK1 ;
DR   Q0TIU6, PEPT_ECOL5 ;  P65803, PEPT_ECOL6 ;  B1IUE0, PEPT_ECOLC ;
DR   P29745, PEPT_ECOLI ;  B7N3N7, PEPT_ECOLU ;  B6I9K6, PEPT_ECOSE ;
DR   Q1RD26, PEPT_ECOUT ;  C5BFN3, PEPT_EDWI9 ;  Q835J5, PEPT_ENTFA ;
DR   Q6D4E3, PEPT_ERWCT ;  B7LQ18, PEPT_ESCF3 ;  B1YFS8, PEPT_EXIS2 ;
DR   C4L0I9, PEPT_EXISA ;  P58794, PEPT_FUSNN ;  P81207, PEPT_FUSNP ;
DR   Q5KZ39, PEPT_GEOKA ;  C5DAS5, PEPT_GEOSW ;  A4INW9, PEPT_GEOTN ;
DR   Q4QK58, PEPT_HAEI8 ;  A5UBV7, PEPT_HAEIE ;  A5UEI5, PEPT_HAEIG ;
DR   P45172, PEPT_HAEIN ;  B8CWQ0, PEPT_HALOH ;  B5XSP2, PEPT_KLEP3 ;
DR   B2GC19, PEPT_LACF3 ;  Q9L4G1, PEPT_LACHE ;  Q9CEM7, PEPT_LACLA ;
DR   P0C2T7, PEPT_LACLC ;  A2RMN0, PEPT_LACLM ;  Q02X44, PEPT_LACLS ;
DR   Q1WTV4, PEPT_LACS1 ;  Q38X92, PEPT_LACSS ;  Q92AM8, PEPT_LISIN ;
DR   C1KW79, PEPT_LISMC ;  Q71YN8, PEPT_LISMF ;  B8DDX7, PEPT_LISMH ;
DR   Q8Y6B1, PEPT_LISMO ;  A0AJN4, PEPT_LISW6 ;  B1HZ48, PEPT_LYSSC ;
DR   B9EAD7, PEPT_MACCJ ;  Q8CXN0, PEPT_OCEIH ;  A6L8T2, PEPT_PARD8 ;
DR   Q9CP05, PEPT_PASMU ;  C6DFW1, PEPT_PECCP ;  Q6LR24, PEPT_PHOPR ;
DR   B5F8C6, PEPT_SALA4 ;  A9MG86, PEPT_SALAR ;  Q57QC7, PEPT_SALCH ;
DR   B5FK77, PEPT_SALDC ;  B5QXA9, PEPT_SALEP ;  B5RB75, PEPT_SALG2 ;
DR   B4TFK5, PEPT_SALHS ;  B4T3R6, PEPT_SALNS ;  Q5PMK2, PEPT_SALPA ;
DR   C0Q764, PEPT_SALPC ;  B5BAE8, PEPT_SALPK ;  B4TTK0, PEPT_SALSV ;
DR   Q8Z7H6, PEPT_SALTI ;  P26311, PEPT_SALTY ;  A8GDC2, PEPT_SERP5 ;
DR   B0TPD4, PEPT_SHEHH ;  A8H6S3, PEPT_SHEPA ;  A8G0I7, PEPT_SHESH ;
DR   B1KHS7, PEPT_SHEWM ;  B2TZ80, PEPT_SHIB3 ;  Q31ZK3, PEPT_SHIBS ;
DR   Q32EY5, PEPT_SHIDS ;  Q0T5R1, PEPT_SHIF8 ;  Q83RR6, PEPT_SHIFL ;
DR   Q3Z2Z2, PEPT_SHISS ;  A7WZN6, PEPT_STAA1 ;  A6TZM2, PEPT_STAA2 ;
DR   Q2FIP8, PEPT_STAA3 ;  Q2G064, PEPT_STAA8 ;  A5IQU7, PEPT_STAA9 ;
DR   Q2YSI6, PEPT_STAAB ;  Q5HHS7, PEPT_STAAC ;  A6QF52, PEPT_STAAE ;
DR   P65805, PEPT_STAAM ;  P65806, PEPT_STAAN ;  Q6GIP8, PEPT_STAAR ;
DR   Q6GB87, PEPT_STAAS ;  A8Z018, PEPT_STAAT ;  Q8NXM6, PEPT_STAAW ;
DR   B9DK09, PEPT_STACT ;  Q5HQY6, PEPT_STAEQ ;  Q8CPZ6, PEPT_STAES ;
DR   Q4L4G8, PEPT_STAHJ ;  Q49VU2, PEPT_STAS1 ;  Q3K0C3, PEPT_STRA1 ;
DR   Q8E4E2, PEPT_STRA3 ;  Q8DYT4, PEPT_STRA5 ;  C0M8H1, PEPT_STRE4 ;
DR   A8AXT3, PEPT_STRGC ;  Q8CWX9, PEPT_STRMU ;  Q9A0F4, PEPT_STRP1 ;
DR   Q04KS5, PEPT_STRP2 ;  P0DD00, PEPT_STRP3 ;  Q5XCU7, PEPT_STRP6 ;
DR   C1C6Y4, PEPT_STRP7 ;  Q8P1H9, PEPT_STRP8 ;  Q1JCH7, PEPT_STRPB ;
DR   Q1JMF5, PEPT_STRPC ;  Q1JHK2, PEPT_STRPD ;  Q1J7C3, PEPT_STRPF ;
DR   A2RF89, PEPT_STRPG ;  B1IBG7, PEPT_STRPI ;  B8ZPG1, PEPT_STRPJ ;
DR   Q48U99, PEPT_STRPM ;  Q97R31, PEPT_STRPN ;  P0DD01, PEPT_STRPQ ;
DR   B2IPG2, PEPT_STRPS ;  B5XKT3, PEPT_STRPZ ;  Q8DQ05, PEPT_STRR6 ;
DR   A4W1Q9, PEPT_STRS2 ;  C0MGM6, PEPT_STRS7 ;  A3CNH0, PEPT_STRSV ;
DR   A4VVF5, PEPT_STRSY ;  Q5LZL2, PEPT_STRT1 ;  Q5M465, PEPT_STRT2 ;
DR   Q03KI4, PEPT_STRTD ;  B9DU35, PEPT_STRU0 ;  C1CE02, PEPT_STRZJ ;
DR   C1CK88, PEPT_STRZP ;  C1CRC4, PEPT_STRZT ;  Q8R922, PEPT_THETN ;
DR   A5EYJ8, PEPT_VIBC3 ;  Q9KMY6, PEPT_VIBCH ;  C3LUK2, PEPT_VIBCM ;
DR   Q5E0X3, PEPT_VIBF1 ;  Q87GX2, PEPT_VIBPA ;  B7VSC8, PEPT_VIBSL ;
DR   Q7MDF5, PEPT_VIBVY ;  A7FH54, PEPT_YERP3 ;  Q1C6R3, PEPT_YERPA ;
DR   B2K719, PEPT_YERPB ;  Q8ZFR0, PEPT_YERPE ;  A9R0M2, PEPT_YERPG ;
DR   Q1CI51, PEPT_YERPN ;  A4TLP0, PEPT_YERPP ;  Q669P7, PEPT_YERPS ;
DR   B1JI59, PEPT_YERPY ;
//
ID   3.4.11.5
DE   Prolyl aminopeptidase.
AN   Cytosol aminopeptidase V.
AN   Pro-X aminopeptidase.
AN   Proline aminopeptidase.
AN   Proline iminopeptidase.
CA   Release of N-terminal proline from a peptide.
CF   Manganese.
CC   -!- Present in the cytosol of mammalian and microbial cells.
CC   -!- In contrast to the mammalian form, the bacterial form of the enzyme
CC       hydrolyzes both polyproline and prolyl-2-naphthylamide.
CC   -!- The mammalian enzyme, which is not specific for prolyl bonds,
CC       is possibly identical with EC 3.4.11.1.
CC   -!- Belongs to peptidase family S33.
CC   -!- Formerly EC 3.4.1.4.
PR   PROSITE; PDOC00548;
DR   P30184, AMPL1_ARATH;  Q2QSB9, AMPL1_ORYSJ;  Q10712, AMPL1_SOLLC;
DR   Q8RX72, AMPL2_ARATH;  Q6K669, AMPL2_ORYSJ;  Q42876, AMPL2_SOLLC;
DR   Q944P7, AMPL3_ARATH;  P00727, AMPL_BOVIN ;  Q5V9F0, AMPL_DICDI ;
DR   Q8SQZ7, AMPL_ENCCU ;  P28838, AMPL_HUMAN ;  P86249, AMPL_MESAU ;
DR   Q9CPY7, AMPL_MOUSE ;  P28839, AMPL_PIG   ;  Q68FS4, AMPL_RAT   ;
DR   P31427, AMPL_SOLTU ;  Q5XGB9, AMPL_XENTR ;  P46547, PIP_AERSO  ;
DR   P93732, PIP_ARATH  ;  P46541, PIP_BACCO  ;  C0ZKI1, PIP_BREBN  ;
DR   C7PDD8, PIP_CHIPD  ;  A5I3F5, PIP_CLOBH  ;  Q184M8, PIP_CLOD6  ;
DR   A5FIF5, PIP_FLAJ1  ;  O05420, PIP_FLAME  ;  Q5FMT1, PIP_LACAC  ;
DR   Q03NE0, PIP_LACBA  ;  D5H0J3, PIP_LACCS  ;  Q1G8L9, PIP_LACDA  ;
DR   P46544, PIP_LACDE  ;  P46542, PIP_LACDL  ;  A8YWL3, PIP_LACH4  ;
DR   P52278, PIP_LACHE  ;  Q890D8, PIP_LACPL  ;  C7TMK0, PIP_LACRL  ;
DR   P47266, PIP_MYCGE  ;  P75092, PIP_MYCPN  ;  P42786, PIP_NEIGO  ;
DR   Q9JUV1, PIP_NEIMA  ;  Q9JZR6, PIP_NEIMB  ;  O83041, PIP_PLEBO  ;
DR   O32449, PIP_SERMA  ;  Q9S2L4, PIP_STRCO  ;  Q97UA2, PIP_SULSO  ;
DR   P96084, PIP_THEAC  ;  Q97A76, PIP_THEVO  ;  P52279, PIP_XANCI  ;
DR   Q9PD69, PIP_XYLFA  ;  Q87DF8, PIP_XYLFT  ;
//
ID   3.4.11.6
DE   Aminopeptidase B.
AN   Arginine aminopeptidase.
AN   Arginyl aminopeptidase.
AN   Arylamidase II.
AN   Cytosol aminopeptidase IV.
CA   Release of N-terminal Arg and Lys from oligopeptides when P1' is not Pro.
CA   Also acts on arylamides of Arg and Lys.
CF   Zinc.
CC   -!- Cytosolic or membrane-associated enzyme from mammalian tissues,
CC       activated by chloride ions and low concentrations of thiol compounds.
CC   -!- One of the activities of the bifunctional enzyme EC 3.3.2.6.
CC   -!- Belongs to peptidase family M1.
PR   PROSITE; PDOC00129;
DR   Q9H4A4, AMPB_HUMAN ;  Q8VCT3, AMPB_MOUSE ;  O09175, AMPB_RAT   ;
DR   P25152, BSAP_BACSU ;
//
ID   3.4.11.7
DE   Glutamyl aminopeptidase.
AN   Aminopeptidase A.
AN   Angiotensinase A.
AN   Aspartate aminopeptidase.
AN   Glutamyl peptidase.
AN   Membrane aminopeptidase II.
CA   Release of N-terminal glutamate (and to a lesser extent aspartate) from a
CA   peptide.
CF   Zinc.
CC   -!- Also acts on L-alpha-glutamyl-peptides.
CC   -!- Calcium-activated and generally membrane-bound.
CC   -!- Belongs to peptidase family M1.
PR   PROSITE; PDOC00129;
DR   Q32LQ0, AMPE_BOVIN ;  Q07075, AMPE_HUMAN ;  P16406, AMPE_MOUSE ;
DR   Q95334, AMPE_PIG   ;  P50123, AMPE_RAT   ;  Q48677, PEPA_LACLM ;
//
ID   3.4.11.8
DE   Transferred entry: 3.4.19.3.
//
ID   3.4.11.9
DE   Xaa-Pro aminopeptidase.
AN   Aminoacylproline aminopeptidase.
AN   Aminopeptidase P.
AN   Proline aminopeptidase.
AN   X-Pro aminopeptidase.
CA   Release of any N-terminal amino acid, including proline, that is linked
CA   to proline, even from a dipeptide or tripeptide.
CF   Manganese or cobalt.
CC   -!- Generally membrane bound enzyme present in both mammalian and
CC       bacterial cells.
CC   -!- Belongs to peptidase family M24B.
PR   PROSITE; PDOC00417;
DR   C0NDZ7, AMPP1_AJECG;  C6HSY3, AMPP1_AJECH;  A6R035, AMPP1_AJECN;
DR   C5GXZ9, AMPP1_AJEDR;  C5K105, AMPP1_AJEDS;  D4ARJ9, AMPP1_ARTBC;
DR   E4USI8, AMPP1_ARTGP;  C5FHR9, AMPP1_ARTOC;  A1CAQ1, AMPP1_ASPCL;
DR   B0Y3V7, AMPP1_ASPFC;  B8NEI6, AMPP1_ASPFN;  Q4WUD3, AMPP1_ASPFU;
DR   A2QGR5, AMPP1_ASPNC;  Q2U7S5, AMPP1_ASPOR;  Q0CDB3, AMPP1_ASPTN;
DR   A6RK67, AMPP1_BOTFB;  Q2H8T2, AMPP1_CHAGB;  C5P7J2, AMPP1_COCP7;
DR   E9CTR7, AMPP1_COCPS;  E3QCU0, AMPP1_COLGM;  A8P5H7, AMPP1_COPC7;
DR   Q5AVF0, AMPP1_EMENI;  B0DZL3, AMPP1_LACBS;  E5ABQ8, AMPP1_LEPMJ;
DR   A4RF35, AMPP1_MAGO7;  E9E9B2, AMPP1_METAQ;  E9EUE6, AMPP1_METAR;
DR   C7Z9Z7, AMPP1_NECH7;  A1DF27, AMPP1_NEOFI;  Q7RYL6, AMPP1_NEUCR;
DR   C1H978, AMPP1_PARBA;  C1GEY4, AMPP1_PARBD;  C0SCV1, AMPP1_PARBP;
DR   B6HQC9, AMPP1_PENCW;  B6QG01, AMPP1_PENMQ;  Q0UFY4, AMPP1_PHANO;
DR   B2AWV6, AMPP1_PODAN;  B2VUU7, AMPP1_PYRTR;  E3S7K9, AMPP1_PYRTT;
DR   A7E4T8, AMPP1_SCLS1;  D1ZKF3, AMPP1_SORMK;  P0A3Z1, AMPP1_STRCO;
DR   P0A3Z2, AMPP1_STRLI;  B8M9W2, AMPP1_TALSN;  D4D891, AMPP1_TRIVH;
DR   D5GAC6, AMPP1_TUBMM;  C9SR45, AMPP1_VERA1;  C0NF18, AMPP2_AJECG;
DR   C6HNY5, AMPP2_AJECH;  A6QYF6, AMPP2_AJECN;  C5GKT2, AMPP2_AJEDR;
DR   C5K0R2, AMPP2_AJEDS;  D4B0B2, AMPP2_ARTBC;  E4V1Q7, AMPP2_ARTGP;
DR   C5FUV0, AMPP2_ARTOC;  A1CNW6, AMPP2_ASPCL;  B0XN37, AMPP2_ASPFC;
DR   B8MZI5, AMPP2_ASPFN;  Q4WRV9, AMPP2_ASPFU;  A2QAW7, AMPP2_ASPNC;
DR   Q2UQH9, AMPP2_ASPOR;  Q0CZM6, AMPP2_ASPTN;  A6SL16, AMPP2_BOTFB;
DR   Q2HA12, AMPP2_CHAGB;  C5PAH2, AMPP2_COCP7;  E9CY14, AMPP2_COCPS;
DR   E3Q897, AMPP2_COLGM;  Q5BF48, AMPP2_EMENI;  A4RQ11, AMPP2_MAGO7;
DR   E9E2J4, AMPP2_METAQ;  E9F9J8, AMPP2_METAR;  C7Z837, AMPP2_NECH7;
DR   A1D1S6, AMPP2_NEOFI;  A7UWH7, AMPP2_NEUCR;  C1H3X3, AMPP2_PARBA;
DR   C1GHS9, AMPP2_PARBD;  C0SDW6, AMPP2_PARBP;  B6HAN0, AMPP2_PENCW;
DR   B6QAW7, AMPP2_PENMQ;  Q0V147, AMPP2_PHANO;  B2AW39, AMPP2_PODAN;
DR   B2WKR4, AMPP2_PYRTR;  E3RNJ5, AMPP2_PYRTT;  A7ENP9, AMPP2_SCLS1;
DR   D1ZQL9, AMPP2_SORMK;  P0A3Z3, AMPP2_STRCO;  P0A3Z4, AMPP2_STRLI;
DR   B8M2W9, AMPP2_TALSN;  D4D6B8, AMPP2_TRIVH;  D5GHP2, AMPP2_TUBMM;
DR   C4JY72, AMPP2_UNCRE;  C9SDK8, AMPP2_VERA1;  C0NIF0, AMPP3_AJECG;
DR   C6H7R7, AMPP3_AJECH;  C5G874, AMPP3_AJEDR;  C5JQ04, AMPP3_AJEDS;
DR   A1CSI0, AMPP3_ASPCL;  B0XW47, AMPP3_ASPFC;  B8NC10, AMPP3_ASPFN;
DR   Q4X267, AMPP3_ASPFU;  A2QKF6, AMPP3_ASPNC;  Q0CFZ0, AMPP3_ASPTN;
DR   A6SDE9, AMPP3_BOTFB;  C5PHM7, AMPP3_COCP7;  E9DDK8, AMPP3_COCPS;
DR   E3QYP0, AMPP3_COLGM;  Q96WX8, AMPP3_EMENI;  E4ZHV7, AMPP3_LEPMJ;
DR   A4RAE9, AMPP3_MAGO7;  E9DV56, AMPP3_METAQ;  E9EK74, AMPP3_METAR;
DR   C7YVN8, AMPP3_NECH7;  A1DG66, AMPP3_NEOFI;  C1H9Q9, AMPP3_PARBA;
DR   C1GD57, AMPP3_PARBD;  C0SHQ0, AMPP3_PARBP;  B6H2M0, AMPP3_PENCW;
DR   B6Q8T5, AMPP3_PENMQ;  Q0U6G5, AMPP3_PHANO;  B2AFW1, AMPP3_PODAN;
DR   B2WMQ2, AMPP3_PYRTR;  E3S6N7, AMPP3_PYRTT;  A7EUB3, AMPP3_SCLS1;
DR   D1ZBF6, AMPP3_SORMK;  B8M0Z4, AMPP3_TALSN;  C4JF09, AMPP3_UNCRE;
DR   C9SEV5, AMPP3_VERA1;  P15034, AMPP_ECOLI ;  P44881, AMPP_HAEIN ;
DR   P47566, AMPP_MYCGE ;  P75313, AMPP_MYCPN ;  Q07825, FRA1_YEAST ;
DR   Q1JPJ2, XPP1_BOVIN ;  Q54G06, XPP1_DICDI ;  Q9NQW7, XPP1_HUMAN ;
DR   Q6P1B1, XPP1_MOUSE ;  O54975, XPP1_RAT   ;  O43895, XPP2_HUMAN ;
DR   Q95333, XPP2_PIG   ;  Q54T46, XPP3_DICDI ;  Q9NQH7, XPP3_HUMAN ;
DR   B7ZMP1, XPP3_MOUSE ;  Q5R9W8, XPP3_PONAB ;  B5DEQ3, XPP3_RAT   ;
//
ID   3.4.11.10
DE   Bacterial leucyl aminopeptidase.
AN   Aeromonas proteolytica aminopeptidase.
CA   Release of an N-terminal amino acid, preferentially leucine, but not
CA   glutamic or aspartic acids.
CF   Zinc.
CC   -!- Similar aminopeptidases were isolated from Escherichia coli and
CC       Staphylococcus thermophilus.
CC   -!- Belongs to peptidase families M17 and M28.
DR   Q8EI85, AMPA1_SHEON;  Q8EH62, AMPA2_SHEON;  B0CCF6, AMPA_ACAM1 ;
DR   Q6FFD8, AMPA_ACIAD ;  B7H1P9, AMPA_ACIB3 ;  B7I309, AMPA_ACIB5 ;
DR   B2I1U0, AMPA_ACIBC ;  Q1IPU7, AMPA_ACIBL ;  B0VMG3, AMPA_ACIBS ;
DR   A3M1A8, AMPA_ACIBT ;  B0VDC8, AMPA_ACIBY ;  C1F4B7, AMPA_ACIC5 ;
DR   B9MJ44, AMPA_ACIET ;  B7J5I9, AMPA_ACIF2 ;  B5EKZ2, AMPA_ACIF5 ;
DR   A1W776, AMPA_ACISJ ;  A3N1A7, AMPA_ACTP2 ;  B3GXY6, AMPA_ACTP7 ;
DR   B0BQ37, AMPA_ACTPJ ;  A6VMX3, AMPA_ACTSZ ;  A0KPF3, AMPA_AERHH ;
DR   Q9Y935, AMPA_AERPE ;  A4SSA7, AMPA_AERS4 ;  B9JCD8, AMPA_AGRRK ;
DR   Q8UGC8, AMPA_AGRT5 ;  B9JUW1, AMPA_AGRVS ;  Q0VSA5, AMPA_ALCBS ;
DR   Q0AB75, AMPA_ALHEH ;  B6EMT2, AMPA_ALISL ;  A6TWW9, AMPA_ALKMQ ;
DR   A8ML24, AMPA_ALKOO ;  Q3M9J6, AMPA_ANAVT ;  O67868, AMPA_AQUAE ;
DR   Q5NXM1, AMPA_AROAE ;  A1K9L5, AMPA_AZOSB ;  C1DPG2, AMPA_AZOVD ;
DR   A7Z8B5, AMPA_BACA2 ;  C3PDF7, AMPA_BACAA ;  C3LC57, AMPA_BACAC ;
DR   A0RKB5, AMPA_BACAH ;  Q81XS5, AMPA_BACAN ;  B7JDH9, AMPA_BACC0 ;
DR   Q72YG1, AMPA_BACC1 ;  B7IMU0, AMPA_BACC2 ;  C1EX85, AMPA_BACC3 ;
DR   B7HBG1, AMPA_BACC4 ;  B7HUR5, AMPA_BACC7 ;  A7GUC8, AMPA_BACCN ;
DR   B9J3C5, AMPA_BACCQ ;  Q816E3, AMPA_BACCR ;  Q632E1, AMPA_BACCZ ;
DR   Q6HBY2, AMPA_BACHK ;  Q65FE6, AMPA_BACLD ;  A8FH04, AMPA_BACP2 ;
DR   O32106, AMPA_BACSU ;  A9VMY8, AMPA_BACWK ;  Q1LTH8, AMPA_BAUCH ;
DR   Q6MH10, AMPA_BDEBA ;  Q7VQT0, AMPA_BLOFL ;  Q2KWX0, AMPA_BORA1 ;
DR   Q7WD42, AMPA_BORBR ;  Q7W5K6, AMPA_BORPA ;  A9IIK3, AMPA_BORPD ;
DR   Q7VW48, AMPA_BORPE ;  Q89MT4, AMPA_BRAJA ;  A5EIB4, AMPA_BRASB ;
DR   Q8YG99, AMPA_BRUME ;  A5VPM3, AMPA_BRUO2 ;  Q8G1M4, AMPA_BRUSU ;
DR   B8D9F2, AMPA_BUCA5 ;  P57448, AMPA_BUCAI ;  Q8K9I0, AMPA_BUCAP ;
DR   B8D7Q4, AMPA_BUCAT ;  Q89AG2, AMPA_BUCBP ;  B1YUW5, AMPA_BURA4 ;
DR   Q1BUE7, AMPA_BURCA ;  B1JWV2, AMPA_BURCC ;  A0K9N9, AMPA_BURCH ;
DR   B4E8G9, AMPA_BURCJ ;  Q0BCQ2, AMPA_BURCM ;  A9AHG9, AMPA_BURM1 ;
DR   A3MLR1, AMPA_BURM7 ;  A2SAC2, AMPA_BURM9 ;  Q62LH2, AMPA_BURMA ;
DR   A1V5Z5, AMPA_BURMS ;  A3NSI1, AMPA_BURP0 ;  Q3JV16, AMPA_BURP1 ;
DR   A3N6U4, AMPA_BURP6 ;  B2JET5, AMPA_BURP8 ;  B2T146, AMPA_BURPP ;
DR   Q63WC3, AMPA_BURPS ;  Q39DS5, AMPA_BURS3 ;  Q2T0C0, AMPA_BURTA ;
DR   A4JGZ2, AMPA_BURVG ;  Q143Y9, AMPA_BURXL ;  Q9PP04, AMPA_CAMJE ;
DR   Q9A7M9, AMPA_CAUCR ;  A0RUA5, AMPA_CENSY ;  Q5L681, AMPA_CHLAB ;
DR   Q823J9, AMPA_CHLCV ;  Q254B9, AMPA_CHLFF ;  B3ED46, AMPA_CHLL2 ;
DR   P38019, AMPA_CHLMU ;  B3QNM5, AMPA_CHLP8 ;  A1BGN2, AMPA_CHLPD ;
DR   Q9Z8F8, AMPA_CHLPN ;  B0B9F3, AMPA_CHLT2 ;  B3QVE8, AMPA_CHLT3 ;
DR   Q3KMX6, AMPA_CHLTA ;  B0BB32, AMPA_CHLTB ;  Q8KD74, AMPA_CHLTE ;
DR   O84049, AMPA_CHLTR ;  Q1QTE5, AMPA_CHRSD ;  Q7NTY9, AMPA_CHRVO ;
DR   A8AMA5, AMPA_CITK8 ;  A5CRI6, AMPA_CLAM3 ;  Q8XHI3, AMPA_CLOPE ;
DR   Q0SQ50, AMPA_CLOPS ;  Q893F8, AMPA_CLOTE ;  Q488M4, AMPA_COLP3 ;
DR   Q6NG90, AMPA_CORDI ;  Q8FNP8, AMPA_COREF ;  Q8NNJ4, AMPA_CORGL ;
DR   Q0K7F5, AMPA_CUPNH ;  Q46XT9, AMPA_CUPPJ ;  B3R663, AMPA_CUPTR ;
DR   B1WR01, AMPA_CYAA5 ;  B8HTK3, AMPA_CYAP4 ;  B7KCB0, AMPA_CYAP7 ;
DR   B7K4A4, AMPA_CYAP8 ;  Q47BG9, AMPA_DECAR ;  C0QC86, AMPA_DESAH ;
DR   B8J457, AMPA_DESDA ;  Q315M7, AMPA_DESDG ;  Q6AJZ3, AMPA_DESPS ;
DR   Q72F03, AMPA_DESVH ;  A8LI79, AMPA_DINSH ;  A7ZVE0, AMPA_ECO24 ;
DR   B7UQR7, AMPA_ECO27 ;  B7MLR5, AMPA_ECO45 ;  B7LCX0, AMPA_ECO55 ;
DR   P68768, AMPA_ECO57 ;  B5Z3L7, AMPA_ECO5E ;  B7NUH4, AMPA_ECO7I ;
DR   B7MSZ3, AMPA_ECO81 ;  B7M9L9, AMPA_ECO8A ;  C4ZRD1, AMPA_ECOBW ;
DR   B1XEN9, AMPA_ECODH ;  A8A816, AMPA_ECOHS ;  A1AJG3, AMPA_ECOK1 ;
DR   Q0T9D1, AMPA_ECOL5 ;  P68766, AMPA_ECOL6 ;  B1ISB1, AMPA_ECOLC ;
DR   P68767, AMPA_ECOLI ;  B7NGJ2, AMPA_ECOLU ;  B6I2H3, AMPA_ECOSE ;
DR   B1LRE5, AMPA_ECOSM ;  Q1R2Z4, AMPA_ECOUT ;  C5BBY4, AMPA_EDWI9 ;
DR   Q5FFZ5, AMPA_EHRRG ;  Q5HAP2, AMPA_EHRRW ;  A4WF25, AMPA_ENT38 ;
DR   Q6DA52, AMPA_ERWCT ;  B2VL42, AMPA_ERWT9 ;  B7LMT2, AMPA_ESCF3 ;
DR   B1YKV4, AMPA_EXIS2 ;  Q8RHT8, AMPA_FUSNN ;  Q74GB4, AMPA_GEOSL ;
DR   C6E543, AMPA_GEOSM ;  C5D720, AMPA_GEOSW ;  A4ISE0, AMPA_GEOTN ;
DR   A5G9C7, AMPA_GEOUR ;  Q7NHC6, AMPA_GLOVI ;  Q5FU70, AMPA_GLUOX ;
DR   Q7VNH9, AMPA_HAEDU ;  Q4QJN7, AMPA_HAEI8 ;  A5UBH1, AMPA_HAEIE ;
DR   A5UFE2, AMPA_HAEIG ;  P45334, AMPA_HAEIN ;  B8F6N9, AMPA_HAEPS ;
DR   Q0I236, AMPA_HAES1 ;  B0UVX4, AMPA_HAES2 ;  Q2SKR0, AMPA_HAHCH ;
DR   A1WUV1, AMPA_HALHL ;  C4K346, AMPA_HAMD5 ;  Q17W06, AMPA_HELAH ;
DR   Q7VGF0, AMPA_HELHP ;  B6JLF2, AMPA_HELP2 ;  B5Z6U1, AMPA_HELPG ;
DR   Q1CTV6, AMPA_HELPH ;  Q9ZLR1, AMPA_HELPJ ;  B2UTQ8, AMPA_HELPS ;
DR   O25294, AMPA_HELPY ;  A4G7P5, AMPA_HERAR ;  Q5QY05, AMPA_IDILO ;
DR   A6T0V4, AMPA_JANMA ;  B5Y2T8, AMPA_KLEP3 ;  A6THI2, AMPA_KLEP7 ;
DR   Q5X1Q9, AMPA_LEGPA ;  A5IAU5, AMPA_LEGPC ;  Q5WTG8, AMPA_LEGPL ;
DR   Q6AFG2, AMPA_LEIXX ;  Q72UC6, AMPA_LEPIC ;  Q8F0Q1, AMPA_LEPIN ;
DR   Q65SA3, AMPA_MANSM ;  Q11HH5, AMPA_MESSB ;  B7KYK4, AMPA_METC4 ;
DR   Q606B9, AMPA_METCA ;  A9VXD6, AMPA_METEP ;  Q1H4U4, AMPA_METFK ;
DR   B1ZAK8, AMPA_METPB ;  A2SH61, AMPA_METPP ;  B1LVC3, AMPA_METRJ ;
DR   B0JL23, AMPA_MICAN ;  C5CCM4, AMPA_MICLC ;  Q7VEN5, AMPA_MYCBO ;
DR   A1KKQ5, AMPA_MYCBP ;  C1AQC8, AMPA_MYCBT ;  P47631, AMPA_MYCGE ;
DR   O32956, AMPA_MYCLE ;  B2HGY2, AMPA_MYCMM ;  Q73YK2, AMPA_MYCPA ;
DR   P75206, AMPA_MYCPN ;  P47707, AMPA_MYCSA ;  A3Q1S2, AMPA_MYCSJ ;
DR   A1UIA8, AMPA_MYCSK ;  Q1B6R7, AMPA_MYCSS ;  A5U4P1, AMPA_MYCTA ;
DR   Q10401, AMPA_MYCTU ;  A0PTP9, AMPA_MYCUA ;  Q9JTI8, AMPA_NEIMA ;
DR   Q0AIF5, AMPA_NITEC ;  Q82X54, AMPA_NITEU ;  Q1QKW6, AMPA_NITHX ;
DR   Q2YB18, AMPA_NITMU ;  Q3JEC8, AMPA_NITOC ;  Q3SS04, AMPA_NITWN ;
DR   Q5YZ53, AMPA_NOCFA ;  B2J3G8, AMPA_NOSP7 ;  Q8Z064, AMPA_NOSS1 ;
DR   A6X259, AMPA_OCHA4 ;  B6JGL8, AMPA_OLICO ;  Q6MC72, AMPA_PARUW ;
DR   P57823, AMPA_PASMU ;  C6DJN2, AMPA_PECCP ;  Q3A831, AMPA_PELCD ;
DR   Q3B4B5, AMPA_PELLD ;  C0QSL9, AMPA_PERMH ;  Q7MZ27, AMPA_PHOLL ;
DR   Q6LUW0, AMPA_PHOPR ;  B1V932, AMPA_PHYAS ;  B3R0N4, AMPA_PHYMT ;
DR   A1VP99, AMPA_POLNA ;  Q12AW5, AMPA_POLSJ ;  Q6A9W5, AMPA_PROAC ;
DR   A3PEG6, AMPA_PROM0 ;  A8G6E3, AMPA_PROM2 ;  A9BBV5, AMPA_PROM4 ;
DR   Q319F5, AMPA_PROM9 ;  Q7VAP4, AMPA_PROMA ;  B4F2N1, AMPA_PROMH ;
DR   Q7V5X8, AMPA_PROMM ;  Q7V0D4, AMPA_PROMP ;  A2BSQ4, AMPA_PROMS ;
DR   Q15PX4, AMPA_PSEA6 ;  A6V0T2, AMPA_PSEA7 ;  B7UVT6, AMPA_PSEA8 ;
DR   Q02RY8, AMPA_PSEAB ;  O68822, AMPA_PSEAE ;  Q1I5F9, AMPA_PSEE4 ;
DR   C3K6G5, AMPA_PSEFS ;  A5VZ69, AMPA_PSEP1 ;  Q3KHM4, AMPA_PSEPF ;
DR   B0KQK8, AMPA_PSEPG ;  Q88P73, AMPA_PSEPK ;  O86436, AMPA_PSEPU ;
DR   B1JBA9, AMPA_PSEPW ;  Q887M0, AMPA_PSESM ;  Q4ZXH7, AMPA_PSEU2 ;
DR   A4VNZ7, AMPA_PSEU5 ;  A1SRZ1, AMPA_PSYIN ;  Q1LJJ6, AMPA_RALME ;
DR   B2UAK8, AMPA_RALPJ ;  Q8XWQ8, AMPA_RALSO ;  B3PUV3, AMPA_RHIE6 ;
DR   Q2KA77, AMPA_RHIEC ;  Q1MIZ4, AMPA_RHIL3 ;  Q984S1, AMPA_RHILO ;
DR   B5ZWY7, AMPA_RHILW ;  Q92QY7, AMPA_RHIME ;  C3M9C8, AMPA_RHISN ;
DR   Q7UJ62, AMPA_RHOBA ;  C1A138, AMPA_RHOE4 ;  Q21WL3, AMPA_RHOFD ;
DR   C1AUB5, AMPA_RHOOB ;  Q2IX74, AMPA_RHOP2 ;  Q07LG0, AMPA_RHOP5 ;
DR   Q6N5B9, AMPA_RHOPA ;  Q215R8, AMPA_RHOPB ;  Q135P8, AMPA_RHOPS ;
DR   B3Q9R8, AMPA_RHOPT ;  A4WRK9, AMPA_RHOS5 ;  Q0SHL0, AMPA_RHOSR ;
DR   C3PMI0, AMPA_RICAE ;  A8GXC3, AMPA_RICB8 ;  Q1RJN2, AMPA_RICBR ;
DR   A8EXL1, AMPA_RICCK ;  Q92J85, AMPA_RICCN ;  Q4UKD7, AMPA_RICFE ;
DR   A8F0Q0, AMPA_RICM5 ;  P27888, AMPA_RICPR ;  C4K1N6, AMPA_RICPU ;
DR   B0BWB2, AMPA_RICRO ;  A8GQW7, AMPA_RICRS ;  Q68XM6, AMPA_RICTY ;
DR   A7NG41, AMPA_ROSCS ;  Q21KZ5, AMPA_SACD2 ;  B5F465, AMPA_SALA4 ;
DR   A9MET9, AMPA_SALAR ;  Q57GC3, AMPA_SALCH ;  B5FSH0, AMPA_SALDC ;
DR   B5R1K2, AMPA_SALEP ;  B5R9L5, AMPA_SALG2 ;  B4TG58, AMPA_SALHS ;
DR   B4T3M4, AMPA_SALNS ;  Q5PJD4, AMPA_SALPA ;  A9N680, AMPA_SALPB ;
DR   C0Q7D6, AMPA_SALPC ;  B5BKS6, AMPA_SALPK ;  B4TTA0, AMPA_SALSV ;
DR   Q8Z116, AMPA_SALTI ;  Q8ZK29, AMPA_SALTY ;  A8G978, AMPA_SERP5 ;
DR   Q12QW7, AMPA_SHEDO ;  Q086N8, AMPA_SHEFN ;  A3QBG2, AMPA_SHELP ;
DR   B8CU18, AMPA_SHEPW ;  A8FS02, AMPA_SHESH ;  B2TYY4, AMPA_SHIB3 ;
DR   Q31TK2, AMPA_SHIBS ;  Q328S1, AMPA_SHIDS ;  Q0SXK0, AMPA_SHIF8 ;
DR   Q83P64, AMPA_SHIFL ;  Q3YU89, AMPA_SHISS ;  A6U7J2, AMPA_SINMW ;
DR   Q2NR41, AMPA_SODGM ;  Q029J4, AMPA_SOLUE ;  B9DIX2, AMPA_STACT ;
DR   Q82AN2, AMPA_STRAW ;  Q9S2Q7, AMPA_STRCO ;  B1VZN5, AMPA_STRGG ;
DR   B4SJ73, AMPA_STRM5 ;  B2FMS4, AMPA_STRMK ;  B2V6F5, AMPA_SULSY ;
DR   Q67NI4, AMPA_SYMTH ;  O06865, AMPA_SYNE7 ;  A0LK12, AMPA_SYNFM ;
DR   Q2JRU4, AMPA_SYNJA ;  Q2JKL5, AMPA_SYNJB ;  B1XK83, AMPA_SYNP2 ;
DR   Q5N569, AMPA_SYNP6 ;  A5GN62, AMPA_SYNPW ;  Q7U8Q1, AMPA_SYNPX ;
DR   A5GV03, AMPA_SYNR3 ;  Q0I816, AMPA_SYNS3 ;  Q3AZE8, AMPA_SYNS9 ;
DR   Q3AHT4, AMPA_SYNSC ;  P73971, AMPA_SYNY3 ;  C5BMG6, AMPA_TERTT ;
DR   Q8DI46, AMPA_THEEB ;  Q31ET3, AMPA_THICR ;  B8GTX6, AMPA_THISH ;
DR   C4LA51, AMPA_TOLAT ;  Q73QZ3, AMPA_TREDE ;  Q11A96, AMPA_TRIEI ;
DR   Q83I32, AMPA_TROW8 ;  Q83G32, AMPA_TROWT ;  C5CLU5, AMPA_VARPS ;
DR   A1WSK3, AMPA_VEREI ;  A5CXK2, AMPA_VESOH ;  A5F5D8, AMPA_VIBC3 ;
DR   P0C6E1, AMPA_VIBCH ;  C3LR42, AMPA_VIBCM ;  Q5E7T8, AMPA_VIBF1 ;
DR   B5F9Q6, AMPA_VIBFM ;  A7MSE5, AMPA_VIBHB ;  Q87LG8, AMPA_VIBPA ;
DR   Q8DCE5, AMPA_VIBVU ;  Q7MHG4, AMPA_VIBVY ;  Q8D295, AMPA_WIGBR ;
DR   Q73IU2, AMPA_WOLPM ;  Q7M8W6, AMPA_WOLSU ;  Q8PGR0, AMPA_XANAC ;
DR   Q3BPA1, AMPA_XANC5 ;  Q4UQP6, AMPA_XANC8 ;  B0RVI0, AMPA_XANCB ;
DR   Q8PCR4, AMPA_XANCP ;  Q2P7G2, AMPA_XANOM ;  B2SPE7, AMPA_XANOP ;
DR   Q5H4N2, AMPA_XANOR ;  A7IFB7, AMPA_XANP2 ;  B2I6L3, AMPA_XYLF2 ;
DR   Q9PH08, AMPA_XYLFA ;  B0U1L5, AMPA_XYLFM ;  Q87F32, AMPA_XYLFT ;
DR   A1JJ31, AMPA_YERE8 ;  A7FML9, AMPA_YERP3 ;  Q1C3R8, AMPA_YERPA ;
DR   B2K3E9, AMPA_YERPB ;  Q8ZBH3, AMPA_YERPE ;  A9R5F5, AMPA_YERPG ;
DR   Q1CM01, AMPA_YERPN ;  A4TQP6, AMPA_YERPP ;  Q66F09, AMPA_YERPS ;
DR   B1JLS9, AMPA_YERPY ;  Q01693, AMPX_VIBPR ;  P25152, BSAP_BACSU ;
//
ID   3.4.11.11
DE   Deleted entry.
//
ID   3.4.11.12
DE   Deleted entry.
//
ID   3.4.11.13
DE   Clostridial aminopeptidase.
AN   Clostridium histolyticum aminopeptidase.
CA   Release of any N-terminal amino acid, including proline and
CA   hydroxyproline, but no cleavage of Xaa-|-Pro.
CF   Manganese or cobalt.
CC   -!- A secreted enzyme from Clostridium histolyticum.
//
ID   3.4.11.14
DE   Cytosol alanyl aminopeptidase.
AN   Aminopolypeptidase.
AN   Arylamidase.
AN   Cytosol aminopeptidase III.
AN   Liver aminopeptidase.
AN   Puromycin-sensitive aminopeptidase.
AN   Soluble alanyl aminopeptidase.
CA   Release of an N-terminal amino acid, preferentially alanine, from a wide
CA   range of peptides, amides and arylamides.
CF   Zinc or cobalt.
CC   -!- A puromycin-sensitive, cobalt-activated zinc-sialoglycoprotein that
CC       is generally cytosolic.
CC   -!- Multiple forms are widely distributed in mammalian tissues and body
CC       fluids.
DR   P55786, PSA_HUMAN  ;  Q11011, PSA_MOUSE  ;
//
ID   3.4.11.15
DE   Aminopeptidase Y.
AN   Aminopeptidase (cobalt-activated).
AN   Aminopeptidase Co.
AN   Lysyl aminopeptidase.
CA   Preferentially, release of N-terminal lysine.
CF   Cobalt.
CC   -!- Inhibited by Zn(2+) and Mn(2+).
CC   -!- Hydrolyzes L-lysyl-4-nitroanilide and, more slowly, L-arginyl-4-
CC       nitroanilide.
CC   -!- Belongs to peptidase family M28B.
DR   Q8TZW4, AMPK_PYRFU ;  P37302, APE3_YEAST ;
//
ID   3.4.11.16
DE   Xaa-Trp aminopeptidase.
AN   Aminopeptidase W.
AN   Aminopeptidase X-Trp.
AN   X-Trp aminopeptidase.
CA   Release of a variety of N-terminal residues (especially glutamate and
CA   leucine) from peptides, provided tryptophan (or at least phenylalanine or
CA   tyrosine) is the penultimate residue. Also acts on Glu-|-Trp, Leu-|-Trp
CA   and a number of other dipeptides.
CF   Zinc.
//
ID   3.4.11.17
DE   Tryptophanyl aminopeptidase.
AN   Tryptophan aminopeptidase.
CA   Preferential release of N-terminal tryptophan.
CF   Manganese.
CC   -!- Also acts on L-tryptophanamide.
CC   -!- From Trichosporon cutaneum.
//
ID   3.4.11.18
DE   Methionyl aminopeptidase.
AN   Methionine aminopeptidase.
AN   Peptidase M.
CA   Release of N-terminal amino acids, preferentially methionine, from
CA   peptides and arylamides.
CF   Cobalt.
CC   -!- Removes the amino-terminal methionine from nascent proteins.
CC   -!- Membrane-bound enzyme present in both prokaryotes and eukaryotes.
CC   -!- Belongs to peptidase family M24A.
PR   PROSITE; PDOC00575;
DR   Q9SLN5, AMP1A_ARATH;  Q9FV52, AMP1B_ARATH;  Q9FV51, AMP1C_ARATH;
DR   Q9FV50, AMP1D_ARATH;  Q4VBS4, AMP1D_DANRE;  Q54VU7, AMP1D_DICDI;
DR   Q6UB28, AMP1D_HUMAN;  Q9CPW9, AMP1D_MOUSE;  C0NIQ4, AMP2A_AJECG;
DR   C5GCN0, AMP2A_AJEDR;  C5JW60, AMP2A_AJEDS;  Q9FV49, AMP2A_ARATH;
DR   E5R3Z8, AMP2A_ARTGP;  C5FF46, AMP2A_ARTOC;  A1CH02, AMP2A_ASPCL;
DR   B0Y5N4, AMP2A_ASPFC;  B8NA06, AMP2A_ASPFN;  Q4WNT9, AMP2A_ASPFU;
DR   A2QHX0, AMP2A_ASPNC;  Q0CL94, AMP2A_ASPTN;  Q2GYA8, AMP2A_CHAGB;
DR   E3QW41, AMP2A_COLGM;  Q5B4X6, AMP2A_EMENI;  E5R4J3, AMP2A_LEPMJ;
DR   C7YS77, AMP2A_NECH7;  A1DA84, AMP2A_NEOFI;  B6HTQ4, AMP2A_PENCW;
DR   B6Q1N3, AMP2A_PENMQ;  B2W1N6, AMP2A_PYRTR;  E3RCY7, AMP2A_PYRTT;
DR   B8LUH2, AMP2A_TALSN;  C0NX86, AMP2B_AJECG;  C5GLJ6, AMP2B_AJEDR;
DR   C5JYZ5, AMP2B_AJEDS;  Q56Y85, AMP2B_ARATH;  E5R278, AMP2B_ARTGP;
DR   C5FEJ1, AMP2B_ARTOC;  A1CCP2, AMP2B_ASPCL;  B0YAX5, AMP2B_ASPFC;
DR   B8NLL0, AMP2B_ASPFN;  Q4WAY7, AMP2B_ASPFU;  A2QAF9, AMP2B_ASPNC;
DR   Q0C838, AMP2B_ASPTN;  Q2GSJ7, AMP2B_CHAGB;  E3QDQ4, AMP2B_COLGM;
DR   Q5BGG1, AMP2B_EMENI;  E4ZYY3, AMP2B_LEPMJ;  C7Z7V7, AMP2B_NECH7;
DR   A1CXT5, AMP2B_NEOFI;  B6H5L5, AMP2B_PENCW;  B6QD96, AMP2B_PENMQ;
DR   B2VW14, AMP2B_PYRTR;  E3RD74, AMP2B_PYRTT;  B8M990, AMP2B_TALSN;
DR   B0XTJ7, AMP2C_ASPFC;  Q4WII3, AMP2C_ASPFU;  A1CYM1, AMP2C_NEOFI;
DR   P19994, AMPM1_BACSU;  A6QLA4, AMPM1_BOVIN;  Q5ZIM5, AMPM1_CHICK;
DR   Q4QRK0, AMPM1_DANRE;  Q54WU3, AMPM1_DICDI;  P53582, AMPM1_HUMAN;
DR   Q8BP48, AMPM1_MOUSE;  Q5RBF3, AMPM1_PONAB;  O59730, AMPM1_SCHPO;
DR   P53579, AMPM1_SYNY3;  Q7ZWV9, AMPM1_XENLA;  Q5I0A0, AMPM1_XENTR;
DR   Q01662, AMPM1_YEAST;  C6HI66, AMPM2_AJECH;  A6RGC8, AMPM2_AJECN;
DR   D4B2G3, AMPM2_ARTBC;  Q2U6H2, AMPM2_ASPOR;  O34484, AMPM2_BACSU;
DR   A6RTU0, AMPM2_BOTFB;  Q3ZC89, AMPM2_BOVIN;  Q59LF9, AMPM2_CANAL;
DR   C4YSA9, AMPM2_CANAW;  B9WJA2, AMPM2_CANDC;  C5M8M4, AMPM2_CANTT;
DR   C4Y1F8, AMPM2_CLAL4;  C5P8Q4, AMPM2_COCP7;  Q6BVB8, AMPM2_DEBHA;
DR   Q55C21, AMPM2_DICDI;  Q8SR45, AMPM2_ENCCU;  Q6XMH6, AMPM2_ENCHE;
DR   Q6XMH7, AMPM2_ENCIN;  P50579, AMPM2_HUMAN;  Q6CP80, AMPM2_KLULA;
DR   B0CRL4, AMPM2_LACBS;  C5DE35, AMPM2_LACTC;  A5E5I9, AMPM2_LODEL;
DR   A4RDI6, AMPM2_MAGO7;  A8QBZ2, AMPM2_MALGO;  O08663, AMPM2_MOUSE;
DR   Q7S7L7, AMPM2_NEUCR;  C1HAB2, AMPM2_PARBA;  C1GLM4, AMPM2_PARBD;
DR   C0SIM8, AMPM2_PARBP;  Q0UTI9, AMPM2_PHANO;  A5DR89, AMPM2_PICGU;
DR   C4R2P3, AMPM2_PICPG;  B2B738, AMPM2_PODAN;  E3L3Q8, AMPM2_PUCGT;
DR   P38062, AMPM2_RAT  ;  D8PR70, AMPM2_SCHCM;  O60085, AMPM2_SCHPO;
DR   A7EZ86, AMPM2_SCLS1;  D1ZEN1, AMPM2_SORMK;  P53580, AMPM2_SYNY3;
DR   D4DE65, AMPM2_TRIVH;  C4JSX6, AMPM2_UNCRE;  C9SB49, AMPM2_VERA1;
DR   Q6CA79, AMPM2_YARLI;  B3LNM2, AMPM2_YEAS1;  C7GSF3, AMPM2_YEAS2;
DR   B5VDQ0, AMPM2_YEAS6;  A6ZKL2, AMPM2_YEAS7;  C8Z3V4, AMPM2_YEAS8;
DR   P38174, AMPM2_YEAST;  P53581, AMPM3_SYNY3;  O66489, AMPM_AQUAE ;
DR   O28438, AMPM_ARCFU ;  Q9Z9J4, AMPM_BACHD ;  O51132, AMPM_BORBU ;
DR   P57324, AMPM_BUCAI ;  Q8K9T1, AMPM_BUCAP ;  Q89AP3, AMPM_BUCBP ;
DR   Q9PL68, AMPM_CHLMU ;  Q9Z6Q0, AMPM_CHLPN ;  O84859, AMPM_CHLTR ;
DR   P69000, AMPM_CLOAB ;  P50614, AMPM_CLOPE ;  P0AE20, AMPM_ECO57 ;
DR   P0AE19, AMPM_ECOL6 ;  P0AE18, AMPM_ECOLI ;  P28617, AMPM_GEOSE ;
DR   P44421, AMPM_HAEIN ;  Q9ZJT0, AMPM_HELPJ ;  P56102, AMPM_HELPY ;
DR   P41392, AMPM_KLEOX ;  P22624, AMPM_METFE ;  Q58725, AMPM_METJA ;
DR   O27355, AMPM_METTH ;  P0A5J3, AMPM_MYCBO ;  Q59509, AMPM_MYCCT ;
DR   O52353, AMPM_MYCGA ;  P47418, AMPM_MYCGE ;  Q11132, AMPM_MYCPN ;
DR   P0A5J2, AMPM_MYCTU ;  Q9UYT4, AMPM_PYRAB ;  P56218, AMPM_PYRFU ;
DR   O58362, AMPM_PYRHO ;  Q5JGD1, AMPM_PYRKO ;  Q9ZCD3, AMPM_RICPR ;
DR   P0A1X7, AMPM_SALTI ;  P0A1X6, AMPM_SALTY ;  P0AE21, AMPM_SHIFL ;
DR   P0A080, AMPM_STAA1 ;  Q5HEN6, AMPM_STAAC ;  P0A078, AMPM_STAAM ;
DR   P99121, AMPM_STAAN ;  Q6GFG9, AMPM_STAAR ;  Q6G846, AMPM_STAAS ;
DR   P0A079, AMPM_STAAW ;  Q5HN46, AMPM_STAEQ ;  Q8CRU9, AMPM_STAES ;
DR   P95963, AMPM_SULSO ;  O83814, AMPM_TREPA ;
//
ID   3.4.11.19
DE   D-stereospecific aminopeptidase.
CA   Release of an N-terminal D-amino acid from a peptide, Xaa-|-Yaa-,
CA   in which Xaa is preferably D-Ala, D-Ser or D-Thr. D-amino acid amides and
CA   methyl esters also are hydrolyzed, as is glycine amide.
CC   -!- A thiol-dependent peptidase known from the bacterium Ochrobactrum
CC       anthropi.
CC   -!- A homolog of EC 3.4.16.4.
CC   -!- Not metal dependent; probably has serine at the active center.
CC   -!- Belongs to peptidase family S12.
DR   B2SD81, DAP_BRUA1  ;  Q2YLB4, DAP_BRUA2  ;  Q579G4, DAP_BRUAB  ;
DR   A9MCM7, DAP_BRUC2  ;  C0RM93, DAP_BRUMB  ;  Q8YD27, DAP_BRUME  ;
DR   A5VVL2, DAP_BRUO2  ;  A9WVV8, DAP_BRUSI  ;  Q8FV99, DAP_BRUSU  ;
DR   Q5FRJ7, DAP_GLUOX  ;  A6WYS5, DAP_OCHA4  ;  Q9ZBA9, DAP_OCHAN  ;
DR   A3PRU3, DAP_RHOS1  ;  Q3IX78, DAP_RHOS4  ;  B9KTA6, DAP_RHOSK  ;
//
ID   3.4.11.20
DE   Aminopeptidase Ey.
CA   Differs from other aminopeptidases in broad specificity for amino acids
CA   in the P1 position and the ability to hydrolyze peptides of four or five
CA   residues that contain Pro in the P1' position.
CF   Zinc.
CC   -!- From the plasma fraction of chicken egg yolk.
CC   -!- Belongs to peptidase family M1.
DR   O57579, AMPN_CHICK ;
//
ID   3.4.11.21
DE   Aspartyl aminopeptidase.
CA   Release of an N-terminal aspartate or glutamate from a peptide, with a
CA   preference for aspartate.
CC   -!- Aminoacyl-arylamides are poor substrates.
CC   -!- Belongs to peptidase family M18.
DR   Q2UPZ7, DNPEP_ASPOR;  Q2HJH1, DNPEP_BOVIN;  Q19087, DNPEP_CAEEL;
DR   Q54M70, DNPEP_DICDI;  Q9ULA0, DNPEP_HUMAN;  Q9Z2W0, DNPEP_MOUSE;
DR   Q5RBT2, DNPEP_PONAB;  O36014, DNPEP_SCHPO;  P38821, DNPEP_YEAST;
//
ID   3.4.11.22
DE   Aminopeptidase I.
AN   Aminopeptidase III.
AN   Aminopeptidase yscI.
AN   Leucine aminopeptidase IV.
AN   Vacuolar aminopeptidase I.
CA   Release of an N-terminal amino acid, preferably a neutral or hydrophobic
CA   one, from a polypeptide. Aminoacyl-arylamides are poor substrates.
CC   -!- Belongs to peptidase family M18.
DR   P14904, AMPL_YEAST ;
//
ID   3.4.11.23
DE   PepB aminopeptidase.
AN   Aminopeptidase B.
AN   Peptidase B.
CA   Release of an N-terminal amino acid, Xaa, from a peptide or arylamide.
CA   Xaa is preferably Glu or Asp but may be other amino acids, including Leu,
CA   Met, His, Cys and Gln.
CC   -!- A 270-kDa protein composed of six 46.3-kDa subunits.
CC   -!- The pH optimum is in the alkaline range and activity is stimulated by
CC       KCl.
CC   -!- Belongs to peptidase family M17.
DR   A8AD60, PEPB_CITK8 ;  A7ZPW6, PEPB_ECO24 ;  B7UGW9, PEPB_ECO27 ;
DR   B7MI07, PEPB_ECO45 ;  B7LDB5, PEPB_ECO55 ;  P58473, PEPB_ECO57 ;
DR   B5Z0Z6, PEPB_ECO5E ;  B7NRH2, PEPB_ECO7I ;  B7MYF7, PEPB_ECO81 ;
DR   B7M7M6, PEPB_ECO8A ;  C4ZX98, PEPB_ECOBW ;  B1XAZ8, PEPB_ECODH ;
DR   A8A329, PEPB_ECOHS ;  A1AE61, PEPB_ECOK1 ;  Q0TEW2, PEPB_ECOL5 ;
DR   Q8FF47, PEPB_ECOL6 ;  B1IWD8, PEPB_ECOLC ;  P37095, PEPB_ECOLI ;
DR   B7N6B0, PEPB_ECOLU ;  B6I595, PEPB_ECOSE ;  B1LNH8, PEPB_ECOSM ;
DR   Q1R8K9, PEPB_ECOUT ;  A4WDA4, PEPB_ENT38 ;  A7MGW9, PEPB_ENTS8 ;
DR   Q6D266, PEPB_ERWCT ;  B7LKB6, PEPB_ESCF3 ;  Q4QM33, PEPB_HAEI8 ;
DR   P58474, PEPB_HAEIN ;  B5XNK4, PEPB_KLEP3 ;  A6TCE4, PEPB_KLEP7 ;
DR   Q9CM16, PEPB_PASMU ;  C6DBI4, PEPB_PECCP ;  Q7N231, PEPB_PHOLL ;
DR   B5F1B3, PEPB_SALA4 ;  A9MHK1, PEPB_SALAR ;  Q57LH5, PEPB_SALCH ;
DR   B5FR78, PEPB_SALDC ;  B5R595, PEPB_SALEP ;  B5RD05, PEPB_SALG2 ;
DR   B4T0R5, PEPB_SALNS ;  A9N1Y3, PEPB_SALPB ;  C0PYL4, PEPB_SALPC ;
DR   Q8Z4N3, PEPB_SALTI ;  Q9RF52, PEPB_SALTY ;  A8GHX6, PEPB_SERP5 ;
DR   B2TXU8, PEPB_SHIB3 ;  Q31XW7, PEPB_SHIBS ;  Q32D41, PEPB_SHIDS ;
DR   Q0T1Z6, PEPB_SHIF8 ;  Q83QK5, PEPB_SHIFL ;  Q3YZ29, PEPB_SHISS ;
DR   Q9KTX5, PEPB_VIBCH ;  A7MU37, PEPB_VIBHB ;  Q87S21, PEPB_VIBPA ;
DR   B7VJT3, PEPB_VIBSL ;  Q8DEZ4, PEPB_VIBVU ;  Q7MNF5, PEPB_VIBVY ;
DR   A7FFX8, PEPB_YERP3 ;  Q1C5H7, PEPB_YERPA ;  B2K9R0, PEPB_YERPB ;
DR   P58475, PEPB_YERPE ;  A9R811, PEPB_YERPG ;  Q1CKA2, PEPB_YERPN ;
DR   A4TMU7, PEPB_YERPP ;  Q667Y8, PEPB_YERPS ;  B1JRZ6, PEPB_YERPY ;
//
ID   3.4.11.24
DE   Aminopeptidase S.
AN   Double-zinc aminopeptidase.
AN   SGAP.
CA   Release of an N-terminal amino acid with a preference for large
CA   hydrophobic amino-terminus residues.
CF   Zinc.
CC   -!- Activated by Ca(2+).
CC   -!- In the presence of Ca(2+), the best substrates are Leu-Phe, Leu-Ser,
CC       Leu-pNA (aminoacyl-p-nitroanilide), Phe-Phe-Phe and Phe-Phe.
CC   -!- Peptides with proline in the P1' position are not substrates.
CC   -!- Belongs to peptidase family M28.
CC   -!- Formerly EC 3.4.11.n1.
DR   P80561, APX_STRGR  ;
//
ID   3.4.11.n1
DE   Transferred entry: 3.4.11.24.
//
ID   3.4.12.1
DE   Transferred entry: 3.4.16.5 and 3.4.16.6.
//
ID   3.4.12.2
DE   Transferred entry: 3.4.17.1.
//
ID   3.4.12.3
DE   Transferred entry: 3.4.17.2.
//
ID   3.4.12.4
DE   Transferred entry: 3.4.16.2.
//
ID   3.4.12.5
DE   Transferred entry: 3.5.1.28.
//
ID   3.4.12.6
DE   Transferred entry: 3.4.17.8.
//
ID   3.4.12.7
DE   Transferred entry: 3.4.17.3.
//
ID   3.4.12.8
DE   Transferred entry: 3.4.17.4.
//
ID   3.4.12.9
DE   Deleted entry.
//
ID   3.4.12.10
DE   Transferred entry: 3.4.19.9.
//
ID   3.4.12.11
DE   Transferred entry: 3.4.17.6.
//
ID   3.4.12.12
DE   Transferred entry: 3.4.16.5 and 3.4.16.6.
//
ID   3.4.12.13
DE   Deleted entry.
//
ID   3.4.13.1
DE   Transferred entry: 3.4.13.18 and 3.4.13.19.
//
ID   3.4.13.2
DE   Transferred entry: 3.4.13.18 and 3.4.13.19.
//
ID   3.4.13.3
DE   Xaa-His dipeptidase.
AN   Aminoacyl-histidine dipeptidase.
AN   Carnosinase.
AN   Homocarnosinase.
AN   X-His dipeptidase.
CA   Hydrolysis of Xaa-|-His dipeptides.
CF   Zinc.
CC   -!- A mammalian cytosolic enzyme.
CC   -!- Also acts on anserine and homocarnosine (but not on homoanserine),
CC       and to a lesser extent on some other aminoacyl-L-histidine
CC       dipeptides.
CC   -!- Activated by thiols; inhibited by metal-chelating agents.
CC   -!- This enzyme may be identical with EC 3.4.13.18.
CC   -!- Belongs to peptidase family M25.
CC   -!- Formerly EC 3.4.3.3 and EC 3.4.13.13.
DR   P15288, PEPD_ECOLI ;  P44817, PEPD_HAEIN ;
//
ID   3.4.13.4
DE   Xaa-Arg dipeptidase.
AN   Aminoacyl-lysine dipeptidase.
AN   N(2)-(4-amino-butyryl)-L-lysine hydrolase.
AN   X-Arg dipeptidase.
CA   Preferential hydrolysis of Xaa-|-Arg, Xaa-|-Lys or Xaa-|-ornithine
CA   dipeptides.
CC   -!- Widely distributed in mammals.
//
ID   3.4.13.5
DE   Xaa-methyl-His dipeptidase.
AN   Aminoacyl-methylhistidine dipeptidase.
AN   Anserinase.
AN   X-methyl-His dipeptidase.
CA   Hydrolysis of anserine (beta-alanyl-|-N(pi)-methyl-L-histidine),
CA   carnosine, homocarnosine, glycyl-|-leucine and other dipeptides with
CA   broad specificity.
CC   -!- Identical with acetylhistidine deacetylase.
CC   -!- Formerly EC 3.4.3.4 and EC 3.5.1.34.
//
ID   3.4.13.6
DE   Transferred entry: 3.4.11.2.
//
ID   3.4.13.7
DE   Glu-Glu dipeptidase.
AN   Alpha-glutamyl-glutamate dipeptidase.
CA   Hydrolysis of the Glu-|-Glu dipeptide.
CC   -!- It is unclear whether the specificity of this enzyme extends to other
CC       alpha-glutamyl dipeptides.
//
ID   3.4.13.8
DE   Transferred entry: 3.4.13.18 and 3.4.13.19.
//
ID   3.4.13.9
DE   Xaa-Pro dipeptidase.
AN   Gamma-peptidase.
AN   Imidodipeptidase.
AN   Peptidase D.
AN   Prolidase.
AN   Proline dipeptidase.
AN   X-Pro dipeptidase.
CA   Hydrolysis of Xaa-|-Pro dipeptides; also acts on aminoacyl-hydroxyproline
CA   analogs. No action on Pro-|-Pro.
CF   Manganese.
CC   -!- Possibly thiol dependent.
CC   -!- Cytosolic from most animal tissues.
CC   -!- Belongs to peptidase family M24A.
CC   -!- Formerly EC 3.4.3.7.
PR   PROSITE; PDOC00417;
DR   Q55E60, PEPD_DICDI ;  P12955, PEPD_HUMAN ;  Q11136, PEPD_MOUSE ;
DR   Q5RFB3, PEPD_PONAB ;  Q5I0D7, PEPD_RAT   ;  Q5QXH5, PEPQ1_IDILO;
DR   Q5QVP2, PEPQ2_IDILO;  A3MYG3, PEPQ_ACTP2 ;  B3GZT0, PEPQ_ACTP7 ;
DR   A0KEL3, PEPQ_AERHH ;  A4STF0, PEPQ_AERS4 ;  Q44238, PEPQ_ALTSX ;
DR   A8ACZ6, PEPQ_CITK8 ;  Q48AT5, PEPQ_COLP3 ;  A7ZU52, PEPQ_ECO24 ;
DR   B7UNH5, PEPQ_ECO27 ;  B7MHD2, PEPQ_ECO45 ;  B7L9A5, PEPQ_ECO55 ;
DR   Q8X8I1, PEPQ_ECO57 ;  B5YY94, PEPQ_ECO5E ;  B7NV19, PEPQ_ECO7I ;
DR   B7N2F3, PEPQ_ECO81 ;  B7M650, PEPQ_ECO8A ;  C5A021, PEPQ_ECOBW ;
DR   B1XAK9, PEPQ_ECODH ;  A8A6V2, PEPQ_ECOHS ;  A1AI34, PEPQ_ECOK1 ;
DR   Q0TAK9, PEPQ_ECOL5 ;  Q8FBI1, PEPQ_ECOL6 ;  B1IW60, PEPQ_ECOLC ;
DR   P21165, PEPQ_ECOLI ;  B7NFE8, PEPQ_ECOLU ;  B6I4I7, PEPQ_ECOSE ;
DR   B1LM33, PEPQ_ECOSM ;  Q1R465, PEPQ_ECOUT ;  C5BCB6, PEPQ_EDWI9 ;
DR   A4WFX3, PEPQ_ENT38 ;  A7MQN9, PEPQ_ENTS8 ;  Q6DAP4, PEPQ_ERWCT ;
DR   B2VFE3, PEPQ_ERWT9 ;  B7LTY8, PEPQ_ESCF3 ;  B8F8H3, PEPQ_HAEPS ;
DR   Q2S6U2, PEPQ_HAHCH ;  B5XYG9, PEPQ_KLEP3 ;  A6TGM5, PEPQ_KLEP7 ;
DR   Q9S6S1, PEPQ_LACDE ;  P46545, PEPQ_LACDL ;  O84913, PEPQ_LACHE ;
DR   A1TXT7, PEPQ_MARAV ;  C6DI64, PEPQ_PECCP ;  Q7MZ93, PEPQ_PHOLL ;
DR   B4EWE3, PEPQ_PROMH ;  Q15ZF7, PEPQ_PSEA6 ;  P77814, PEPQ_PSEHA ;
DR   Q3IJ21, PEPQ_PSEHT ;  P81535, PEPQ_PYRFU ;  O58885, PEPQ_PYRHO ;
DR   B5EZW1, PEPQ_SALA4 ;  A9MIX1, PEPQ_SALAR ;  Q57HM5, PEPQ_SALCH ;
DR   B5FNX9, PEPQ_SALDC ;  B5QW86, PEPQ_SALEP ;  B5RFL5, PEPQ_SALG2 ;
DR   B4TBS6, PEPQ_SALHS ;  B4SZ86, PEPQ_SALNS ;  Q5PKQ1, PEPQ_SALPA ;
DR   A9MYB1, PEPQ_SALPB ;  C0Q3F4, PEPQ_SALPC ;  B5BIZ1, PEPQ_SALPK ;
DR   B4TNZ2, PEPQ_SALSV ;  Q9L6L4, PEPQ_SALTI ;  Q7CPD4, PEPQ_SALTY ;
DR   A8G8D3, PEPQ_SERP5 ;  A1S1I9, PEPQ_SHEAM ;  B8E3R4, PEPQ_SHEB2 ;
DR   A3CYJ5, PEPQ_SHEB5 ;  A6WHA1, PEPQ_SHEB8 ;  A9KU92, PEPQ_SHEB9 ;
DR   Q12TB3, PEPQ_SHEDO ;  Q08A38, PEPQ_SHEFN ;  B0TLC0, PEPQ_SHEHH ;
DR   A3Q8U5, PEPQ_SHELP ;  Q8EKR8, PEPQ_SHEON ;  A8GYG1, PEPQ_SHEPA ;
DR   A4Y1B7, PEPQ_SHEPC ;  B8CHA2, PEPQ_SHEPW ;  A0KR51, PEPQ_SHESA ;
DR   A8FP64, PEPQ_SHESH ;  Q0HPB6, PEPQ_SHESM ;  Q0I0T2, PEPQ_SHESR ;
DR   A1RDW7, PEPQ_SHESW ;  B1KCZ4, PEPQ_SHEWM ;  B2TVJ6, PEPQ_SHIB3 ;
DR   Q31UE2, PEPQ_SHIBS ;  Q32A22, PEPQ_SHIDS ;  Q0SZ37, PEPQ_SHIF8 ;
DR   Q83PG0, PEPQ_SHIFL ;  Q3YVC0, PEPQ_SHISS ;  Q2NWT2, PEPQ_SODGM ;
DR   B4SI11, PEPQ_STRM5 ;  B2FT23, PEPQ_STRMK ;  Q8PH57, PEPQ_XANAC ;
DR   Q3BPR2, PEPQ_XANC5 ;  Q4UY33, PEPQ_XANC8 ;  B0RP90, PEPQ_XANCB ;
DR   Q8P5S9, PEPQ_XANCP ;  Q2P6N8, PEPQ_XANOM ;  Q5H3T0, PEPQ_XANOR ;
DR   A1JIG5, PEPQ_YERE8 ;  A7FDF3, PEPQ_YERP3 ;  Q1C2C5, PEPQ_YERPA ;
DR   B2K0Z7, PEPQ_YERPB ;  Q0WAP4, PEPQ_YERPE ;  A9R755, PEPQ_YERPG ;
DR   Q1CN98, PEPQ_YERPN ;  A4TR26, PEPQ_YERPP ;  Q66FR7, PEPQ_YERPS ;
DR   B1JP62, PEPQ_YERPY ;
//
ID   3.4.13.10
DE   Transferred entry: 3.4.19.5.
//
ID   3.4.13.11
DE   Transferred entry: 3.4.13.18 and 3.4.13.19.
//
ID   3.4.13.12
DE   Met-Xaa dipeptidase.
AN   Dipeptidase M.
AN   Met-X dipeptidase.
AN   Methionyl dipeptidase.
CA   Hydrolysis of Met-|-Xaa dipeptides.
CF   Manganese.
CC   -!- Escherichia coli enzyme with thiol dependence.
//
ID   3.4.13.13
DE   Transferred entry: 3.4.13.3.
//
ID   3.4.13.14
DE   Deleted entry.
//
ID   3.4.13.15
DE   Transferred entry: 3.4.13.18 and 3.4.13.19.
//
ID   3.4.13.16
DE   Deleted entry.
//
ID   3.4.13.17
DE   Non-stereospecific dipeptidase.
AN   D-(or L-)aminoacyl-dipeptidase.
AN   Peptidyl-D-amino acid hydrolase.
CA   Hydrolysis of dipeptides containing either D- or L-amino acids or both.
CC   -!- A digestive enzyme of cephalopods.
//
ID   3.4.13.18
DE   Cytosol nonspecific dipeptidase.
AN   Cytosol non-specific dipeptidase.
AN   Glycyl-glycine dipeptidase.
AN   Glycyl-leucine dipeptidase.
AN   N(2)-beta-alanylarginine dipeptidase.
AN   Peptidase A.
AN   Pro-X dipeptidase.
AN   Prolinase.
AN   Prolyl dipeptidase.
AN   Prolylglycine dipeptidase.
CA   Hydrolysis of dipeptides, preferentially hydrophobic dipeptides including
CA   prolyl amino acids.
CF   Zinc.
CC   -!- Broad specificity, varying somewhat with source species.
CC   -!- Activated and stabilized by dithiothreitol and manganese.
CC   -!- Inhibited by bestatin and leucine.
CC   -!- Belongs to peptidase family M20.
CC   -!- Formerly EC 3.4.3.1, EC 3.4.3.2, EC 3.4.3.6, EC 3.4.13.1,
CC       EC 3.4.13.2, EC 3.4.13.8, EC 3.4.13.11 and EC 3.4.13.15.
DR   Q3ZC84, CNDP2_BOVIN;  Q96KP4, CNDP2_HUMAN;  Q9D1A2, CNDP2_MOUSE;
DR   Q5R432, CNDP2_PONAB;  Q6Q0N1, CNDP2_RAT  ;
//
ID   3.4.13.19
DE   Membrane dipeptidase.
AN   Dehydropeptidase I.
AN   DPH I.
AN   Microsomal dipeptidase.
AN   Renal dipeptidase.
CA   Hydrolysis of dipeptides.
CF   Zinc.
CC   -!- Membrane bound, with broad specificity.
CC   -!- Abundant in the kidney cortex.
CC   -!- Inhibited by bestatin and cilastatin.
CC   -!- Belongs to peptidase family M19.
CC   -!- Formerly EC 3.4.3.1, EC 3.4.3.2, EC 3.4.3.6, EC 3.4.13.1,
CC       EC 3.4.13.2, EC 3.4.13.8, EC 3.4.13.11 and EC 3.4.13.15.
PR   PROSITE; PDOC00678;
DR   O14124, DPEH1_SCHPO;  O59832, DPEH2_SCHPO;  D4B2N2, DPEP1_ARTBC;
DR   E5R2Q7, DPEP1_ARTGP;  C5FK77, DPEP1_ARTOC;  Q3SZM7, DPEP1_BOVIN;
DR   C5PCZ0, DPEP1_COCP7;  E9D269, DPEP1_COCPS;  P16444, DPEP1_HUMAN;
DR   P31428, DPEP1_MOUSE;  P22412, DPEP1_PIG  ;  P31429, DPEP1_RABIT;
DR   P31430, DPEP1_RAT  ;  P43477, DPEP1_SHEEP;  D4DEJ7, DPEP1_TRIVH;
DR   C5PCN6, DPEP2_COCP7;  E9CV02, DPEP2_COCPS;  Q9H4A9, DPEP2_HUMAN;
DR   Q8C255, DPEP2_MOUSE;  C7ZIE1, DPEP2_NECH7;  Q5M872, DPEP2_RAT  ;
DR   B8LWT1, DPEP2_TALSN;  C4JQN7, DPEP2_UNCRE;  Q9H4B8, DPEP3_HUMAN;
DR   Q4R7M2, DPEP3_MACFA;  Q9DA79, DPEP3_MOUSE;  Q5U2X4, DPEP3_RAT  ;
//
ID   3.4.13.20
DE   Beta-Ala-His dipeptidase.
AN   Serum carnosinase.
CA   Preferential hydrolysis of the beta-Ala-|-His dipeptide (carnosine),
CA   and also anserine, Xaa-|-His dipeptides and other dipeptides including
CA   homocarnosine.
CC   -!- Present in the serum of humans and higher primates, but not in the
CC       serum of other mammals.
CC   -!- Activated by Cd(2+) and citrate.
CC   -!- Belongs to peptidase family M20.
DR   Q96KN2, CNDP1_HUMAN;  Q8BUG2, CNDP1_MOUSE;  Q66HG3, CNDP1_RAT  ;
//
ID   3.4.13.21
DE   Dipeptidase E.
AN   Aspartyl dipeptidase.
AN   PepE gene product (Salmonella typhimurium).
AN   Peptidase E.
CA   Dipeptidase E catalyzes the hydrolysis of dipeptides Asp-|-Xaa. It does
CA   not act on peptides with N-terminal Glu, Asn or Gln, nor does it cleave
CA   isoaspartyl peptides.
CC   -!- A free carboxy group is not absolutely required in the substrate
CC       since Asp-Phe-NH(2) and Asp-Phe-OMe are hydrolyzed somewhat more
CC       slowly than dipeptides with free C-termini.
CC   -!- No peptide larger than a C-blocked dipeptide is known to be a
CC       substrate.
CC   -!- Asp-NH-Np is hydrolyzed and is a convenient substrate for routine
CC       assay.
CC   -!- The enzyme is most active near pH 7.0, and is not inhibited by
CC       di-isopropylfluorophosphate or phenylmethanesulfonyl fluoride.
CC   -!- Belongs to peptidase family S51.
DR   A3N0N1, PEPE_ACTP2 ;  B3H1L0, PEPE_ACTP7 ;  B0BPF6, PEPE_ACTPJ ;
DR   A8ANB2, PEPE_CITK8 ;  Q9VYH3, PEPE_DROME ;  A7ZUN5, PEPE_ECO24 ;
DR   B7UPH5, PEPE_ECO27 ;  B7MJ04, PEPE_ECO45 ;  B7LAW3, PEPE_ECO55 ;
DR   P0A7C7, PEPE_ECO57 ;  B5Z0B3, PEPE_ECO5E ;  B7NRV3, PEPE_ECO7I ;
DR   B7MRE6, PEPE_ECO81 ;  B7M7S7, PEPE_ECO8A ;  C5A0V8, PEPE_ECOBW ;
DR   B1XC20, PEPE_ECODH ;  A8A7B7, PEPE_ECOHS ;  A1AIJ2, PEPE_ECOK1 ;
DR   Q0TA47, PEPE_ECOL5 ;  Q8FB55, PEPE_ECOL6 ;  B1IUN1, PEPE_ECOLC ;
DR   P0A7C6, PEPE_ECOLI ;  B7NFV7, PEPE_ECOLU ;  B6I5M9, PEPE_ECOSE ;
DR   B1LPH7, PEPE_ECOSM ;  Q1R3S5, PEPE_ECOUT ;  Q4QMU5, PEPE_HAEI8 ;
DR   A5UHB4, PEPE_HAEIG ;  P44766, PEPE_HAEIN ;  P58493, PEPE_NOSS1 ;
DR   Q9CNH7, PEPE_PASMU ;  B5F1K4, PEPE_SALA4 ;  A9MHB2, PEPE_SALAR ;
DR   Q57H37, PEPE_SALCH ;  B5R7Q9, PEPE_SALG2 ;  B4TDG7, PEPE_SALHS ;
DR   B4T1N0, PEPE_SALNS ;  Q5PKZ6, PEPE_SALPA ;  A9N1I0, PEPE_SALPB ;
DR   C0Q494, PEPE_SALPC ;  B5BJT4, PEPE_SALPK ;  B4TQM9, PEPE_SALSV ;
DR   P58494, PEPE_SALTI ;  P36936, PEPE_SALTY ;  A1S5J3, PEPE_SHEAM ;
DR   B8E718, PEPE_SHEB2 ;  A3D5N8, PEPE_SHEB5 ;  A6WPJ2, PEPE_SHEB8 ;
DR   A9L579, PEPE_SHEB9 ;  Q12MB3, PEPE_SHEDO ;  Q8EDL3, PEPE_SHEON ;
DR   A4Y7X3, PEPE_SHEPC ;  A0KY73, PEPE_SHESA ;  Q0HHP4, PEPE_SHESM ;
DR   Q0HTZ6, PEPE_SHESR ;  A1RIL5, PEPE_SHESW ;  B2TX41, PEPE_SHIB3 ;
DR   Q31TY2, PEPE_SHIBS ;  Q0SXY7, PEPE_SHIF8 ;  Q83PB5, PEPE_SHIFL ;
DR   Q3YUW9, PEPE_SHISS ;  Q93RZ5, PEPE_STRCO ;  Q91642, PEPE_XENLA ;
//
ID   3.4.13.22
DE   D-Ala-D-Ala dipeptidase.
AN   D-alanyl-D-alanine dipeptidase.
CA   D-Ala-D-Ala + H(2)O = 2 D-Ala.
CF   Zinc.
CC   -!- Protects Enterococcus faecium from the antibiotic vancomycin, which
CC       can bind to the -D-Ala-D-Ala sequence at the C-terminus of the
CC       peptidoglycan pentapeptide.
CC   -!- Reduces the availability of the free dipeptide D-Ala-D-Ala, which is
CC       the precursor for this pentapeptide sequence, allowing D-Ala-(R)-
CC       lactate (for which vancomycin has much less affinity) to be added to
CC       the cell wall instead.
CC   -!- The enzyme is stereospecific, as L-Ala-L-Ala, D-Ala-L-Ala and L-Ala-
CC       D-Ala are not substrates.
CC   -!- Belongs to peptidase family M15.
DR   P77790, DDPX_ECOLI ;  P74268, DDPX_SYNY3 ;  Q47749, VANX_ENTFA ;
DR   Q06241, VANX_ENTFC ;  Q9XAK6, VANX_STRCO ;
//
ID   3.4.14.1
DE   Dipeptidyl-peptidase I.
AN   Cathepsin C.
AN   Cathepsin J.
AN   Dipeptidyl aminopeptidase I.
AN   Dipeptidyl transferase.
CA   Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, except when Xaa is
CA   Arg or Lys, or Yaa or Zaa is Pro.
CC   -!- Also polymerizes dipeptide amides, arylamides and esters at neutral
CC       pH.
CC   -!- Cl(-)-dependent lysosomal cysteine-type peptidase.
CC   -!- Belongs to peptidase family C1.
CC   -!- Formerly EC 3.4.4.9.
PR   PROSITE; PDOC00126;
DR   Q3ZCJ8, CATC_BOVIN ;  O97578, CATC_CANFA ;  P53634, CATC_HUMAN ;
DR   Q60HG6, CATC_MACFA ;  P97821, CATC_MOUSE ;  Q5RB02, CATC_PONAB ;
DR   P80067, CATC_RAT   ;
//
ID   3.4.14.2
DE   Dipeptidyl-peptidase II.
AN   Carboxytripeptidase.
AN   Dipeptidyl aminopeptidase II.
AN   Dipeptidyl arylamidase II.
AN   DPP II.
AN   Quiescent cell proline dipeptidase.
CA   Release of an N-terminal dipeptide, Xaa-Yaa-|-, preferentially when Yaa
CA   is Ala or Pro. Substrates are oligopeptides, preferentially tripeptides.
CC   -!- A lysosomal serine-type peptidase maximally active at acidic pH.
CC   -!- Cleaves Lys-Ala-naphthylamide.
CC   -!- Belongs to peptidase family S28.
DR   Q9UHL4, DPP2_HUMAN ;  Q9ET22, DPP2_MOUSE ;  Q9EPB1, DPP2_RAT   ;
//
ID   3.4.14.3
DE   Transferred entry: 3.4.19.1.
//
ID   3.4.14.4
DE   Dipeptidyl-peptidase III.
AN   Dipeptidyl aminopeptidase III.
AN   Dipeptidyl arylamidase III.
AN   DPP III.
AN   Enkephalinase B.
AN   Red cell angiotensinase.
CA   Release of an N-terminal dipeptide from a peptide comprising four or more
CA   residues, with broad specificity. Also acts on dipeptidyl
CA   2-naphthylamides.
CC   -!- A cytosolic peptidase that is active at neutral pH.
CC   -!- It has broad activity on peptides, although it is highly selective
CC       for Arg-Arg-2-naphthylamide, at pH 9.2.
CC   -!- Active in the hydrolysis of enkephalins.
CC   -!- Belongs to peptidase family M49.
DR   P83681, DPP3_BLACR ;  Q557H1, DPP3_DICDI ;  Q9VHR8, DPP3_DROME ;
DR   Q9NY33, DPP3_HUMAN ;  Q99KK7, DPP3_MOUSE ;  A7RZW4, DPP3_NEMVE ;
DR   O55096, DPP3_RAT   ;  Q08225, DPP3_YEAST ;
//
ID   3.4.14.5
DE   Dipeptidyl-peptidase IV.
AN   Dipeptidyl aminopeptidase IV.
AN   DPP IV.
AN   Gly-Pro naphthylamidase.
AN   Post-proline dipeptidyl aminopeptidase IV.
AN   Xaa-Pro-dipeptidylaminopeptidase.
CA   Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide,
CA   preferentially when Yaa is Pro, provided Zaa is neither Pro nor
CA   hydroxyproline.
CC   -!- A membrane-bound serine-type peptidase in mammals.
CC   -!- EC 3.4.14.11 catalyzes a similar reaction.
CC   -!- Belongs to peptidase family S9B.
PR   PROSITE; PDOC00587;
DR   F0U7H7, DAPB_AJEC8 ;  C0NUQ8, DAPB_AJECG ;  C6HRC7, DAPB_AJECH ;
DR   A6RBI0, DAPB_AJECN ;  C5GVF3, DAPB_AJEDR ;  C5JC30, DAPB_AJEDS ;
DR   D4AQT0, DAPB_ARTBC ;  E4UYL6, DAPB_ARTGP ;  C5FYZ3, DAPB_ARTOC ;
DR   A1CJQ1, DAPB_ASPCL ;  B0XYK8, DAPB_ASPFC ;  B8N076, DAPB_ASPFN ;
DR   Q4WX13, DAPB_ASPFU ;  A2QEK7, DAPB_ASPNC ;  Q96VT7, DAPB_ASPNG ;
DR   Q2UPW4, DAPB_ASPOR ;  Q0CXB1, DAPB_ASPTN ;  A6SL49, DAPB_BOTFB ;
DR   Q2HF90, DAPB_CHAGB ;  C5P334, DAPB_COCP7 ;  E9CUF4, DAPB_COCPS ;
DR   E3QKD2, DAPB_COLGM ;  Q5B934, DAPB_EMENI ;  F0XS04, DAPB_GROCL ;
DR   A4QYQ5, DAPB_MAGO7 ;  E9ED72, DAPB_METAQ ;  E9ETL5, DAPB_METAR ;
DR   C7YYG9, DAPB_NECH7 ;  A1D7R6, DAPB_NEOFI ;  Q7SHU8, DAPB_NEUCR ;
DR   C1GT79, DAPB_PARBA ;  C1FZL3, DAPB_PARBD ;  C0S7H1, DAPB_PARBP ;
DR   B6HFS8, DAPB_PENCW ;  B6QVW4, DAPB_PENMQ ;  Q0UVK7, DAPB_PHANO ;
DR   B2A951, DAPB_PODAN ;  B2WC36, DAPB_PYRTR ;  E3S9K3, DAPB_PYRTT ;
DR   A7EQZ1, DAPB_SCLS1 ;  D1Z9B4, DAPB_SORMK ;  B8MTH6, DAPB_TALSN ;
DR   D4DCG0, DAPB_TRIVH ;  D5GM60, DAPB_TUBMM ;  C4JHY5, DAPB_UNCRE ;
DR   C9SJ15, DAPB_VERA1 ;  D4APE2, DPP4_ARTBC ;  C5FJE3, DPP4_ARTOC ;
DR   A0S5V9, DPP4_ARTOT ;  A1CHP1, DPP4_ASPCL ;  B0Y6C5, DPP4_ASPFC ;
DR   B8N970, DPP4_ASPFN ;  Q4WPH9, DPP4_ASPFU ;  Q2UH35, DPP4_ASPOR ;
DR   P81425, DPP4_BOVIN ;  Q5AZ42, DPP4_EMENI ;  Q9N2I7, DPP4_FELCA ;
DR   P27487, DPP4_HUMAN ;  P28843, DPP4_MOUSE ;  A1CX29, DPP4_NEOFI ;
DR   P22411, DPP4_PIG   ;  P14740, DPP4_RAT   ;  A7UKV8, DPP4_TRIEQ ;
DR   Q5J6J3, DPP4_TRIRU ;  B6V868, DPP4_TRITO ;  D4CZ59, DPP4_TRIVH ;
DR   Q6V1X1, DPP8_HUMAN ;  Q80YA7, DPP8_MOUSE ;  Q86TI2, DPP9_HUMAN ;
DR   Q8BVG4, DPP9_MOUSE ;  B1A4F7, VDDP4_VESVU;  B2D0J4, VDPP4_APIME;
//
ID   3.4.14.6
DE   Dipeptidyl-dipeptidase.
AN   Dipeptidyl ligase.
AN   Dipeptidyl tetrapeptide hydrolase.
AN   Tetrapeptide dipeptidase.
CA   Preferential release of dipeptides from a tetrapeptide, e.g. Ala-
CA   Gly-|-Ala-Gly. Acts more slowly on Ala-Ala-|-Ala-Ala and Gly-Gly-|-Gly-
CA   Gly.
CC   -!- Tetrapeptides are formed from Ala-Ala, Gly-Gly, Ala-Gly and Gly-Ala
CC       without prior activation of the carboxy group.
CC   -!- Activated by thiols.
CC   -!- From cabbage (Brassica oleracea).
//
ID   3.4.14.7
DE   Deleted entry.
//
ID   3.4.14.8
DE   Transferred entry: 3.4.14.9 and 3.4.14.10.
//
ID   3.4.14.9
DE   Tripeptidyl-peptidase I.
AN   Tripeptidyl aminopeptidase.
AN   Tripeptidyl peptidase.
CA   Release of an N-terminal tripeptide from a polypeptide, but also has
CA   endopeptidase activity.
CC   -!- A lysosomal enzyme that is active at acidic pH.
CC   -!- Belongs to peptidase family S53.
CC   -!- Formerly included in EC 3.4.14.8.
DR   Q0V8B6, TPP1_BOVIN ;  Q9XSB8, TPP1_CANFA ;  Q55CT0, TPP1_DICDI ;
DR   O14773, TPP1_HUMAN ;  Q60HH1, TPP1_MACFA ;  O89023, TPP1_MOUSE ;
DR   Q5IS74, TPP1_PANTR ;  Q5RFL1, TPP1_PONAB ;  Q9EQV6, TPP1_RAT   ;
//
ID   3.4.14.10
DE   Tripeptidyl-peptidase II.
AN   Tripeptidyl aminopeptidase.
AN   Tripeptidyl peptidase.
CA   Release of an N-terminal tripeptide from a polypeptide.
CC   -!- A cytosolic enzyme active at neutral pH.
CC   -!- Inhibited by diisopropyl fluorophosphate.
CC   -!- Belongs to peptidase family S8.
CC   -!- Formerly EC 3.4.14.8.
PR   PROSITE; PDOC00125;
DR   A5PK39, TPP2_BOVIN ;  Q9V6K1, TPP2_DROME ;  P29144, TPP2_HUMAN ;
DR   Q64514, TPP2_MOUSE ;  Q64560, TPP2_RAT   ;  Q9UT05, TPP2_SCHPO ;
//
ID   3.4.14.11
DE   Xaa-Pro dipeptidyl-peptidase.
AN   X-Pro dipeptidyl-peptidase.
AN   X-prolyl dipeptidyl aminopeptidase.
CA   Hydrolyzes Xaa-Pro-|- bonds to release unblocked, N-terminal dipeptides
CA   from substrates including Ala-Pro-|-p-nitroanilide and (sequentially)
CA   Tyr-Pro-|-Phe-Pro-|-Gly-Pro-|-Ile.
CC   -!- EC 3.4.14.5 catalyzes a similar reaction.
CC   -!- Belongs to peptidase family S15.
DR   Q81PE9, PEPX_BACAN ;  Q81CB2, PEPX_BACCR ;  Q03PM5, PEPX_LACBA ;
DR   Q038E8, PEPX_LACC3 ;  B3WEZ5, PEPX_LACCB ;  Q1G9E8, PEPX_LACDA ;
DR   Q049K4, PEPX_LACDB ;  Q9Z5K9, PEPX_LACDE ;  P40334, PEPX_LACDL ;
DR   A8YVY9, PEPX_LACH4 ;  Q59485, PEPX_LACHE ;  Q9CE01, PEPX_LACLA ;
DR   P22346, PEPX_LACLC ;  A2RNK1, PEPX_LACLM ;  Q02W78, PEPX_LACLS ;
DR   Q88YC0, PEPX_LACPL ;  Q9RDW6, PEPX_LACRH ;  Q1WRZ1, PEPX_LACS1 ;
DR   Q03H46, PEPX_PEDPA ;  P59825, PEPX_RHOBA ;  Q3JZF9, PEPX_STRA1 ;
DR   Q8E3H8, PEPX_STRA3 ;  Q8DXW0, PEPX_STRA5 ;  Q82MI6, PEPX_STRAW ;
DR   C0MAI3, PEPX_STRE4 ;  B4U108, PEPX_STREM ;  A8AUU3, PEPX_STRGC ;
DR   Q93M42, PEPX_STRGN ;  Q8L376, PEPX_STRMC ;  Q8DVS2, PEPX_STRMU ;
DR   Q99Y58, PEPX_STRP1 ;  Q04L26, PEPX_STRP2 ;  P0DD36, PEPX_STRP3 ;
DR   B5E3Z6, PEPX_STRP4 ;  Q5XA40, PEPX_STRP6 ;  C1C6M6, PEPX_STRP7 ;
DR   Q8NZH6, PEPX_STRP8 ;  Q1JA07, PEPX_STRPB ;  Q1JK54, PEPX_STRPC ;
DR   Q1JF50, PEPX_STRPD ;  Q1J501, PEPX_STRPF ;  A2RCP2, PEPX_STRPG ;
DR   B1IB64, PEPX_STRPI ;  B8ZNT8, PEPX_STRPJ ;  Q48RI5, PEPX_STRPM ;
DR   Q97RC8, PEPX_STRPN ;  P0DD37, PEPX_STRPQ ;  B2IP51, PEPX_STRPS ;
DR   B5XI61, PEPX_STRPZ ;  Q8DQ87, PEPX_STRR6 ;  C0MEP5, PEPX_STRS7 ;
DR   A3CKT0, PEPX_STRSV ;  Q5LYA9, PEPX_STRT1 ;  Q5M2X3, PEPX_STRT2 ;
DR   Q03J44, PEPX_STRTD ;  Q8GMC0, PEPX_STRTR ;  B9DVM1, PEPX_STRU0 ;
DR   C1CDP2, PEPX_STRZJ ;  C1CJY2, PEPX_STRZP ;  C1CRZ9, PEPX_STRZT ;
//
ID   3.4.14.12
DE   Xaa-Xaa-Pro tripeptidyl-peptidase.
AN   Prolyl tripeptidyl peptidase.
AN   Prolyltripeptidyl amino peptidase.
AN   Prolyltripeptidyl aminopeptidase.
AN   PTP-A.
AN   TPP.
CA   Hydrolysis of Xaa-Xaa-Pro-|-Yaa- releasing the N-terminal tripeptide of a
CA   peptide with Pro as the third residue (position P1) and where Yaa is not
CA   proline.
CC   -!- This cell-surface-associated serine exopeptidase is found in the
CC       Gram-negative, anaerobic bacterium Porphyromonas gingivalis, which
CC       has been implicated in adult periodontal disease.
CC   -!- The enzyme releases tripeptides from the free amino terminus of
CC       peptides and small proteins, such as interleukin-6.
CC   -!- The enzyme possesses an absolute requirement for a proline residue at
CC       the P1 position but is completely inactivated by a proline residue at
CC       the P1' position.
CC   -!- The size of the peptide does not affect the rate of reaction.
DR   B2RJX3, PTP_PORG3  ;  Q7MUW6, PTP_PORGI  ;
//
ID   3.4.15.1
DE   Peptidyl-dipeptidase A.
AN   ACE.
AN   Angiotensin I-converting enzyme.
AN   Carboxycathepsin.
AN   Dipeptidyl carboxypeptidase I.
AN   Kininase II.
AN   Peptidase P.
AN   Peptidyl dipeptidase I.
CA   Release of a C-terminal dipeptide, oligopeptide-|-Xaa-Yaa, when Xaa is
CA   not Pro, and Yaa is neither Asp nor Glu. Thus, conversion of angiotensin
CA   I to angiotensin II, with increase in vasoconstrictor activity, but no
CA   action on angiotensin II.
CF   Zinc.
CC   -!- Cl(-)-dependent.
CC   -!- A glycoprotein that is generally membrane-bound.
CC   -!- Active at neutral pH.
CC   -!- Only single dipeptides are released from angiotensin I and bradykinin
CC       because of the lack of activity on bonds involving proline.
CC   -!- Belongs to peptidase family M2.
PR   PROSITE; PDOC00129;
DR   Q9VLJ6, ACER_DROME ;  P12820, ACE_BOVIN  ;  Q10751, ACE_CHICK  ;
DR   Q10714, ACE_DROME  ;  Q10715, ACE_HAEIX  ;  P12821, ACE_HUMAN  ;
DR   Q50JE5, ACE_MESAU  ;  P09470, ACE_MOUSE  ;  Q9GLN7, ACE_PANTR  ;
DR   P12822, ACE_RABIT  ;  P47820, ACE_RAT    ;  Q6Q4G4, ACE_THETS  ;
//
ID   3.4.15.2
DE   Transferred entry: 3.4.19.2.
//
ID   3.4.15.3
DE   Transferred entry: 3.4.15.5.
//
ID   3.4.15.4
DE   Peptidyl-dipeptidase B.
AN   Atrial di-(tri-)peptidyl carboxylase.
AN   Atriopeptin convertase.
AN   Dipeptidyl carboxyhydrolase.
CA   Release of a C-terminal dipeptide or exceptionally a tripeptide.
CF   Zinc.
CC   -!- A membrane-bound, zinc metallopeptidase located in mammalian atrial,
CC       but not ventricular, myocytes.
CC   -!- Although it is capable of converting the 126-residue atriopeptin III
CC       directly to atriopeptin I by releasing a C-terminal tripeptide Phe-
CC       Arg-Tyr, it is generally restricted to the release of dipeptides.
CC   -!- In contrast to EC 3.4.15.1 it displays no chlorine dependence and
CC       shows no action on angiotensin I.
CC   -!- Conversely, peptidyl-dipeptidase a is unable to release Phe-Arg from
CC       the C-terminus of atriopeptin II.
//
ID   3.4.15.5
DE   Peptidyl-dipeptidase Dcp.
AN   Dipeptidyl carboxypeptidase.
CA   Hydrolysis of unblocked, C-terminal dipeptides from oligopeptides, with
CA   broad specificity. Does not hydrolyze bonds in which P1' is Pro, or both
CA   P1 and P1' are Gly.
CF   Zinc.
CC   -!- Inhibited by captopril, as is peptidyl-dipeptidase A.
CC   -!- Belongs to peptidase family M3.
CC   -!- Formerly EC 3.4.15.3.
PR   PROSITE; PDOC00129;
DR   P24171, DCP_ECOLI  ;  P27236, DCP_SALTY  ;
//
ID   3.4.15.6
DE   Cyanophycinase.
AN   Beta-asp-Arg hydrolyzing enzyme.
AN   CGPase.
AN   Cyanophycin degrading enzyme.
AN   Cyanophycin granule polypeptidase.
CA   (L-Asp(4-L-Arg))(n) + H(2)O = (L-Asp(4-L-Arg))(n-1) + L-Asp(4-L-Arg).
CC   -!- Highly specific for the branched polypeptide cyanophycin and does not
CC       hydrolyze poly-L-aspartate or poly-L-arginine.
CC   -!- A serine-type exopeptidase.
CC   -!- Belongs to peptidase family S51.
DR   O86108, CPHB_ANAVT ;  P58562, CPHB_NOSS1 ;  P0C8P2, CPHB_SYNEL ;
DR   P73832, CPHB_SYNY3 ;  P56946, CPHB_SYNY8 ;  P0C8P3, CPHB_THEEB ;
DR   Q8KQN8, CPHE_PSEAG ;
//
ID   3.4.16.1
DE   Transferred entry: 3.4.16.5 and 3.4.16.6.
//
ID   3.4.16.2
DE   Lysosomal Pro-Xaa carboxypeptidase.
AN   Angiotensinase C.
AN   Lysosomal carboxypeptidase C.
AN   Lysosomal Pro-X carboxypeptidase.
AN   Proline carboxypeptidase.
AN   Prolyl carboxypeptidase.
CA   Cleavage of a -Pro-|-Xaa bond to release a C-terminal amino acid.
CC   -!- A lysosomal peptidase active at acidic pH that inactivates
CC       angiotensin II.
CC   -!- Inhibited by diisopropyl fluorophosphate.
CC   -!- Belongs to peptidase family S28.
CC   -!- Formerly EC 3.4.12.4.
DR   Q2TA14, PCP_BOVIN  ;  P42785, PCP_HUMAN  ;  Q7TMR0, PCP_MOUSE  ;
DR   Q5RBU7, PCP_PONAB  ;
//
ID   3.4.16.3
DE   Transferred entry: 3.4.16.5 and 3.4.16.6.
//
ID   3.4.16.4
DE   Serine-type D-Ala-D-Ala carboxypeptidase.
AN   D-alanyl-D-alanine carboxypeptidase.
AN   DD-peptidase.
AN   DD-transpeptidase.
CA   Preferential cleavage: (Ac)(2)-L-Lys-D-Ala-|-D-Ala. Also transpeptidation
CA   of peptidyl-alanyl moieties that are N-acyl substituents of D-alanine.
CC   -!- A group of bacterial enzymes, membrane-bound.
CC   -!- Inhibited by beta-lactam antibiotics, which acylate the active site
CC       serine in the enzyme.
CC   -!- Distinct from EC 3.4.17.14.
CC   -!- Belongs to peptidase families S11, S12 and S13.
DR   P08750, DACA_BACSU ;  P0AEB4, DACA_ECO57 ;  P0AEB3, DACA_ECOL6 ;
DR   P0AEB2, DACA_ECOLI ;  Q05523, DACA_GEOSE ;  P44466, DACA_HAEIN ;
DR   P35150, DACB_BACSU ;  P24228, DACB_ECOLI ;  P45161, DACB_HAEIN ;
DR   P39844, DACC_BACSU ;  P08506, DACC_ECOLI ;  P33013, DACD_ECOLI ;
DR   P37604, DACD_SALTY ;  P38422, DACF_BACSU ;  P39042, DACX_STRSK ;
DR   P39045, DAC_ACTSP  ;  P15555, DAC_STRSR  ;  Q86I79, PSCA_DICDI ;
DR   Q47746, VANY_ENTFA ;  P37711, VANY_ENTFC ;
//
ID   3.4.16.5
DE   Carboxypeptidase C.
AN   Carboxypeptidase Y.
AN   Cathepsin A.
AN   Lysosomal protective protein.
AN   Serine-type carboxypeptidase I.
CA   Release of a C-terminal amino acid with broad specificity.
CC   -!- Carboxypeptidases of broad specificity with optimum pH 4.5-6.0,
CC       inhibited by the action of diisopropyl fluorophosphate, and sensitive
CC       to thiol-blocking reagents.
CC   -!- This enzyme is probably also identical to lysosomal tyrosine
CC       carboxypeptidase.
CC   -!- Belongs to peptidase family S10.
CC   -!- Formerly EC 3.4.12.1, EC 3.4.12.12, EC 3.4.16.1, EC 3.4.16.3 and
CC       EC 3.4.21.13.
PR   PROSITE; PDOC00122;
DR   P07519, CBP1_HORVU ;  P37890, CBP1_ORYSJ ;  P21529, CBP3_HORVU ;
DR   P37891, CBP3_ORYSJ ;  P11515, CBP3_WHEAT ;  C0NX46, CBPYA_AJECG;
DR   A6RGA0, CBPYA_AJECN;  C5GEU5, CBPYA_AJEDR;  C5K1Y9, CBPYA_AJEDS;
DR   D4AZ71, CBPYA_ARTBC;  E4USS9, CBPYA_ARTGP;  C5FWJ1, CBPYA_ARTOC;
DR   A1CUJ5, CBPYA_ASPCL;  B8NXS9, CBPYA_ASPFN;  Q5VJG9, CBPYA_ASPFU;
DR   A5AB21, CBPYA_ASPNC;  Q2TYA1, CBPYA_ASPOR;  Q0CSD3, CBPYA_ASPTN;
DR   A6RUD7, CBPYA_BOTFB;  Q2H9G6, CBPYA_CHAGB;  C5P212, CBPYA_COCP7;
DR   E3QR43, CBPYA_COLGM;  Q96VC4, CBPYA_EMENI;  E5A7I6, CBPYA_LEPMJ;
DR   A4RPY8, CBPYA_MAGO7;  C7YQJ2, CBPYA_NECH7;  A1DP75, CBPYA_NEOFI;
DR   Q7RXW8, CBPYA_NEUCR;  C1GXD8, CBPYA_PARBA;  C1GG77, CBPYA_PARBD;
DR   C0SGX7, CBPYA_PARBP;  B6HPP6, CBPYA_PENCW;  B6QAN5, CBPYA_PENMQ;
DR   Q0V1R1, CBPYA_PHANO;  B2AWD5, CBPYA_PODAN;  B2WKF1, CBPYA_PYRTR;
DR   A7F4H5, CBPYA_SCLS1;  D1ZG13, CBPYA_SORMK;  B8M044, CBPYA_TALSN;
DR   B8XGR4, CBPYA_TRIEQ;  Q5J6J0, CBPYA_TRIRU;  A5YCB8, CBPYA_TRITO;
DR   D4DLI1, CBPYA_TRIVH;  C4JNM2, CBPYA_UNCRE;  P30574, CBPY_CANAL ;
DR   P52710, CBPY_PICPG ;  O13849, CBPY_SCHPO ;  P00729, CBPY_YEAST ;
DR   Q3MI05, PPGB_BOVIN ;  P10619, PPGB_HUMAN ;  P16675, PPGB_MOUSE ;
//
ID   3.4.16.6
DE   Carboxypeptidase D.
AN   Carboxypeptidase KEX1.
AN   Carboxypeptidase S1.
CA   Preferential release of a C-terminal arginine or lysine residue.
CC   -!- Carboxypeptidases of broad specificity with optimum pH 4.5-6.0,
CC       inhibited by the action of diisopropyl fluorophosphate, and sensitive
CC       to thiol-blocking reagents.
CC   -!- Belongs to peptidase family S10.
CC   -!- Formerly EC 3.4.12.1, EC 3.4.12.12, EC 3.4.16.1, EC 3.4.16.3 and
CC       EC 3.4.21.13.
PR   PROSITE; PDOC00122;
DR   P55747, CBP21_HORVU;  P55748, CBP22_HORVU;  P52711, CBP23_HORVU;
DR   P08818, CBP2_HORVU ;  P08819, CBP2_WHEAT ;  P34946, CPS1_PENJA ;
DR   A6QX86, KEX1_AJECN ;  C5GC75, KEX1_AJEDR ;  C5JN54, KEX1_AJEDS ;
DR   D4B5L8, KEX1_ARTBC ;  C5FTV7, KEX1_ARTOC ;  Q752M5, KEX1_ASHGO ;
DR   A1CQL5, KEX1_ASPCL ;  B0XQ16, KEX1_ASPFC ;  Q4WTK9, KEX1_ASPFU ;
DR   A2QPW5, KEX1_ASPNC ;  Q2UPI1, KEX1_ASPOR ;  Q0CCR9, KEX1_ASPTN ;
DR   Q5AFP8, KEX1_CANAL ;  C4YTG0, KEX1_CANAW ;  B9WJJ7, KEX1_CANDC ;
DR   Q6FTM9, KEX1_CANGA ;  C5MFP8, KEX1_CANTT ;  Q2GYB7, KEX1_CHAGB ;
DR   C4Y8B4, KEX1_CLAL4 ;  C5P635, KEX1_COCP7 ;  E9CS37, KEX1_COCPS ;
DR   E3QDT3, KEX1_COLGM ;  A8NYP0, KEX1_COPC7 ;  E6R6G5, KEX1_CRYGW ;
DR   B5RUL7, KEX1_DEBHA ;  Q5BDJ6, KEX1_EMENI ;  Q6CKK4, KEX1_KLULA ;
DR   C5DLM9, KEX1_LACTC ;  E5R540, KEX1_LEPMJ ;  A5E751, KEX1_LODEL ;
DR   A4RE47, KEX1_MAGO7 ;  E9E1Z2, KEX1_METAQ ;  E9ESM3, KEX1_METAR ;
DR   C7YRS6, KEX1_NECH7 ;  A1D3I1, KEX1_NEOFI ;  Q1K722, KEX1_NEUCR ;
DR   C1GP85, KEX1_PARBA ;  C1G2I2, KEX1_PARBD ;  C0SGJ2, KEX1_PARBP ;
DR   B6H7A4, KEX1_PENCW ;  B6QQZ9, KEX1_PENMQ ;  Q0USX0, KEX1_PHANO ;
DR   D0MVS1, KEX1_PHYIT ;  E7R7R2, KEX1_PICAD ;  A5DAT0, KEX1_PICGU ;
DR   O74702, KEX1_PICPA ;  C4QZV7, KEX1_PICPG ;  B2B762, KEX1_PODAN ;
DR   E3L8A5, KEX1_PUCGT ;  B2W340, KEX1_PYRTR ;  B6K7U7, KEX1_SCHJY ;
DR   O60123, KEX1_SCHPO ;  A7EYY7, KEX1_SCLS1 ;  D1ZEM2, KEX1_SORMK ;
DR   B8M719, KEX1_TALSN ;  D5G4B1, KEX1_TUBMM ;  C4JTD3, KEX1_UNCRE ;
DR   Q4P8U8, KEX1_USTMA ;  A7TLB3, KEX1_VANPO ;  C9S688, KEX1_VERA1 ;
DR   Q6CFP3, KEX1_YARLI ;  C7GWZ2, KEX1_YEAS2 ;  C8Z852, KEX1_YEAS8 ;
DR   E7NHF8, KEX1_YEASO ;  P09620, KEX1_YEAST ;  C5DT72, KEX1_ZYGRC ;
DR   Q9M099, SCP24_ARATH;  D4AIF1, SCPA_ARTBC ;  B6V867, SCPA_TRITO ;
DR   D4DD24, SCPA_TRIVH ;  D4AP52, SCPB_ARTBC ;  C5FGX1, SCPB_ARTOC ;
DR   Q5J6J2, SCPB_TRIRU ;  C5FW30, SPCA_ARTOC ;  A7UKV5, SPCA_TRIEQ ;
DR   Q5J6J1, SPCA_TRIRU ;
//
ID   3.4.17.1
DE   Carboxypeptidase A.
AN   Carboxypolypeptidase.
CA   Release of a C-terminal amino acid, but little or no action with -Asp,
CA   -Glu, -Arg, -Lys or -Pro.
CF   Zinc.
CC   -!- Isolated from cattle, pig and dogfish pancreas, and other sources
CC       including mast cells and skeletal muscle.
CC   -!- Belongs to peptidase family M14.
CC   -!- Formerly EC 3.4.2.1 and EC 3.4.12.2.
PR   PROSITE; PDOC00123;
DR   P00730, CBPA1_BOVIN;  P15085, CBPA1_HUMAN;  Q7TPZ8, CBPA1_MOUSE;
DR   P09954, CBPA1_PIG  ;  P00731, CBPA1_RAT  ;  P15088, CBPA3_HUMAN;
DR   P15089, CBPA3_MOUSE;  P21961, CBPA3_RAT  ;  Q8WXQ8, CBPA5_HUMAN;
DR   Q4R7R2, CBPA5_MACFA;  Q8R4H4, CBPA5_MOUSE;  Q8N4T0, CBPA6_HUMAN;
DR   Q5U901, CBPA6_MOUSE;
//
ID   3.4.17.2
DE   Carboxypeptidase B.
AN   Protaminase.
CA   Preferential release of a C-terminal lysine or arginine amino acid.
CF   Zinc.
CC   -!- Isolated from cattle, pig and dogfish pancreas, and other sources,
CC       including skin fibroblasts and adrenal medulla.
CC   -!- Belongs to peptidase family M14.
CC   -!- Formerly EC 3.4.2.2 and EC 3.4.12.3.
PR   PROSITE; PDOC00123;
DR   P00732, CBPB1_BOVIN;  P55261, CBPB1_CANFA;  P15086, CBPB1_HUMAN;
DR   P09955, CBPB1_PIG  ;  P19223, CBPB1_RAT  ;  P04069, CBPB_ASTFL ;
DR   P19628, CBPB_PROAT ;
//
ID   3.4.17.3
DE   Lysine carboxypeptidase.
AN   Anaphylatoxin inactivator.
AN   Arginine carboxypeptidase.
AN   Carboxypeptidase N.
AN   Kininase I.
AN   Lysine(arginine) carboxypeptidase.
CA   Release of a C-terminal basic amino acid, preferentially lysine.
CF   Zinc.
CC   -!- Inactivates bradykinin and anaphylatoxins in blood plasma.
CC   -!- Belongs to peptidase family M14.
CC   -!- Formerly EC 3.4.12.7.
PR   PROSITE; PDOC00123;
DR   Q2KJ83, CBPN_BOVIN ;  P15169, CBPN_HUMAN ;  Q9JJN5, CBPN_MOUSE ;
DR   Q9EQV8, CBPN_RAT   ;
//
ID   3.4.17.4
DE   Gly-Xaa carboxypeptidase.
AN   Carboxypeptidase A.
AN   Carboxypeptidase S.
AN   Gly-X carboxypeptidase.
AN   Glycine carboxypeptidase.
CA   Release of a C-terminal amino acid from a peptide in which glycine is the
CA   penultimate amino acid, e.g. Z-Gly-|-Leu.
CC   -!- Belongs to peptidase family M20A.
CC   -!- Formerly EC 3.4.2.3, EC 3.4.12.8 and EC 3.4.17.9.
PR   PROSITE; PDOC00613;
DR   P27614, CBPS_YEAST ;
//
ID   3.4.17.5
DE   Deleted entry.
//
ID   3.4.17.6
DE   Alanine carboxypeptidase.
CA   Release of a C-terminal alanine from a peptide or a variety of pteroyl or
CA   acyl groups.
CC   -!- Peptide can be replaced by a pteroyl group or variety of acyl groups.
CC   -!- The enzyme from Corynebacterium equi also hydrolyzes N-benzoylglycine
CC       and N-benzoyl-L-aminobutyric acid.
CC   -!- Formerly EC 3.4.12.11.
DR   P13722, CBAL_GEOSE ;
//
ID   3.4.17.7
DE   Transferred entry: 3.5.1.28.
//
ID   3.4.17.8
DE   Muramoylpentapeptide carboxypeptidase.
AN   Carboxypeptidase D-alanyl-D-alanine.
AN   D-alanine carboxypeptidase.
AN   D-alanine-D-alanine-carboxypeptidase.
AN   D-alanyl-D-alanine carboxypeptidase.
AN   D-alanyl-D-alanine peptidase.
AN   DD-carboxypeptidase.
AN   DD-peptidase.
AN   PBP5.
AN   Penicillin binding protein 5.
AN   UDP-N-acetylmuramoyl-tetrapeptidyl-D-alanine alanine-hydrolase.
CA   Cleavage of the bond UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-6-
CA   carboxy-L-lysyl-D-alanyl-|-D-alanine.
CF   Zinc.
CC   -!- Does not cleave the C-terminal D-alanine from the product of the
CC       above reaction, UDP-N-acetyl-muramoyl-L-alanyl-D-gamma-glutamyl-6-
CC       carboxy-L-lysyl-D-alanine.
CC   -!- Competitively inhibited by penicillins and cephalosporins.
CC   -!- Belongs to peptidase family M15.
CC   -!- Formerly EC 3.4.12.6.
//
ID   3.4.17.9
DE   Transferred entry: 3.4.17.4.
//
ID   3.4.17.10
DE   Carboxypeptidase E.
AN   Carboxypeptidase H.
AN   Enkephalin convertase.
CA   Release of C-terminal arginine or lysine residues from polypeptides.
CF   Zinc.
CC   -!- Activated by Co(2+).
CC   -!- Inhibited by 1,10-phenanthroline and other chelating agents.
CC   -!- pH optimum 5.6.
CC   -!- Located in storage granules of secretory cells, and active in
CC       processing of protein hormones and bioactive peptides.
CC   -!- Distinct from EC 3.4.17.2 and EC 3.4.17.3.
CC   -!- Belongs to peptidase family M14.
PR   PROSITE; PDOC00123;
DR   P04836, CBPE_BOVIN ;  P16870, CBPE_HUMAN ;  P37892, CBPE_LOPAM ;
DR   Q4R4M3, CBPE_MACFA ;  Q00493, CBPE_MOUSE ;  A5A6K7, CBPE_PANTR ;
DR   P15087, CBPE_RAT   ;
//
ID   3.4.17.11
DE   Glutamate carboxypeptidase.
AN   Carboxypeptidase G.
AN   Carboxypeptidase G1.
AN   Carboxypeptidase G2.
CA   Release of C-terminal glutamate residues from a wide range of N-acylating
CA   moieties, including peptidyl, aminoacyl, benzoyl, benzyloxycarbonyl,
CA   folyl and pteroyl groups.
CF   Zinc.
CC   -!- Produced by pseudomonads, Flavobacterium sp. and Acinetobacter sp.
CC   -!- Its ability to hydrolyze pteroyl-L-glutamate (folic acid) has led to
CC       its use as a folate-depleting, antitumor agent.
CC   -!- Belongs to peptidase family M20A.
PR   PROSITE; PDOC00613;
DR   P06621, CBPG_PSES6 ;
//
ID   3.4.17.12
DE   Carboxypeptidase M.
CA   Cleavage of C-terminal arginine or lysine residues from polypeptides.
CF   Zinc.
CC   -!- A membrane-bound enzyme optimally active at neutral pH.
CC   -!- Distinct from EC 3.4.17.3 and EC 3.4.17.10.
CC   -!- Belongs to peptidase family M14.
PR   PROSITE; PDOC00123;
DR   P14384, CBPM_HUMAN ;  Q80V42, CBPM_MOUSE ;  Q5RFD6, CBPM_PONAB ;
//
ID   3.4.17.13
DE   Muramoyltetrapeptide carboxypeptidase.
AN   Carboxypeptidase IIW.
CA   GlcNAc-MurNAc-L-alanyl-gamma-D-glutamyl-meso-diaminopimelyl-D-alanine +
CA   H(2)O = GlcNAc-MurNAc-L-alanyl-gamma-D-glutamyl-meso-diaminopimelate +
CA   D-alanine.
CC   -!- Variants are known from various microorganisms.
CC   -!- Involved in peptidoglycan synthesis, catalyzing both decarboxylation
CC       and transpeptidation.
CC   -!- Stimulated by divalent cations such as magnesium and calcium, but not
CC       zinc.
CC   -!- Inhibited by thiol-blocking reagents, but unaffected by penicillin.
DR   Q8XDJ8, LDCA_ECO57 ;  P59238, LDCA_ECOL6 ;  P76008, LDCA_ECOLI ;
DR   Q9HTZ1, LDC_PSEAE  ;  Q9VYX7, PGPSA_DROME;
//
ID   3.4.17.14
DE   Zinc D-Ala-D-Ala carboxypeptidase.
AN   D-alanyl-D-alanine hydrolase.
AN   Zn(2+) G peptidase.
CA   Cleavage of the bond: (Ac)(2)-L-lysyl-D-alanyl-|-D-alanine.
CF   Zinc.
CC   -!- Catalyzes carboxypeptidation but not transpeptidation reactions
CC       involved in bacterial cell wall metabolism.
CC   -!- Weakly inhibited by beta-lactams.
CC   -!- Distinct from EC 3.4.16.4.
DR   P00733, CBPM_STRAL ;
//
ID   3.4.17.15
DE   Carboxypeptidase A2.
CA   Similar to that of carboxypeptidase A (EC 3.4.17.1), but with a
CA   preference for bulkier C-terminal residues.
CF   Zinc.
CC   -!- Isolated from rat pancreas but not present in cattle pancreas.
CC   -!- Belongs to peptidase family M14.
PR   PROSITE; PDOC00123;
DR   P48052, CBPA2_HUMAN;  Q504N0, CBPA2_MOUSE;  P19222, CBPA2_RAT  ;
//
ID   3.4.17.16
DE   Membrane Pro-Xaa carboxypeptidase.
AN   Carboxypeptidase P.
AN   Membrane Pro-X carboxypeptidase.
AN   Microsomal carboxypeptidase.
CA   Release of a C-terminal residue other than proline, by preferential
CA   cleavage of a prolyl bond.
CC   -!- One of the renal brush border exopeptidases.
//
ID   3.4.17.17
DE   Tubulinyl-Tyr carboxypeptidase.
AN   Carboxypeptidase-tubulin.
AN   Soluble carboxypeptidase.
CA   Cleavage of the -Glu-|-Tyr bond to release the C-terminal tyrosine
CA   residue from the native tyrosinated tubulin. Inactive on Z-Glu-Tyr.
CC   -!- Active at neutral pH, from brain.
//
ID   3.4.17.18
DE   Carboxypeptidase T.
CA   Releases a C-terminal residue, which may be hydrophobic or positively
CA   charged.
CF   Zinc.
CC   -!- Belongs to peptidase family M14.
PR   PROSITE; PDOC00123;
DR   P29068, CBPT_THEVU ;
//
ID   3.4.17.19
DE   Carboxypeptidase Taq.
AN   Thermostable carboxypeptidase 1.
CA   Release of a C-terminal amino acid with broad specificity, except for
CA   -Pro.
CF   Zinc.
CC   -!- Most active at 80 degrees Celsius.
CC   -!- Belongs to peptidase family M32.
PR   PROSITE; PDOC00129;
DR   P42663, CTAQ_THEAQ ;
//
ID   3.4.17.20
DE   Carboxypeptidase U.
AN   Arginine carboxypeptidase.
AN   Carboxypeptidase B2.
AN   Carboxypeptidase R.
AN   Plasma carboxypeptidase B.
AN   TAFI.
AN   Thrombin-activatable fibrinolysis inhibitor.
CA   Release of C-terminal Arg and Lys from a polypeptide.
CF   Zinc.
CC   -!- Pro-carboxypeptidase U in plasma is activated by thrombin or plasmin
CC       during clotting to form the unstable carboxypeptidase U.
CC   -!- Activity similar to that of the more stable lysine carboxypeptidase,
CC       except no preference is shown for Lys over Arg.
CC   -!- Belongs to peptidase family M14.
DR   Q2KIG3, CBPB2_BOVIN;  Q96IY4, CBPB2_HUMAN;  Q9JHH6, CBPB2_MOUSE;
DR   Q9EQV9, CBPB2_RAT  ;
//
ID   3.4.17.21
DE   Glutamate carboxypeptidase II.
AN   Folate hydrolase.
AN   N-acetylated-gamma-linked-acidic dipeptidase.
AN   NAALADase.
AN   Pteroylpoly-gamma-glutamate carboxypeptidase.
CA   Release of an unsubstituted, C-terminal glutamyl residue, typically from
CA   Ac-Asp-Glu or folylpoly-gamma-glutamates.
CF   Zinc.
CC   -!- Hydrolyzes alpha-peptide bonds in Ac-Asp-Glu, Asp-Glu, and Glu-Glu,
CC       but also gamma-glutamyl bonds in gamma-Glu-Glu and folylpoly-gamma-
CC       glutamates.
CC   -!- With folylpoly-gamma-glutamates, shows processive carboxypeptidase
CC       activity to produce pteroylmonoglutamate.
CC   -!- Does not hydrolyze Ac-beta-Asp-Glu.
CC   -!- Inhibited by quisqualic acid, Ac-beta-Asp-Glu, and 2-phosphonomethyl-
CC       pentanedioate.
CC   -!- The release of C-terminal glutamate from folylpoly-gamma-glutamates
CC       is also catalyzed by EC 3.4.17.11 and EC 3.4.19.9.
CC   -!- Belongs to peptidase family M28.
CC   -!- Formerly EC 3.4.19.8.
DR   Q04609, FOLH1_HUMAN;  O35409, FOLH1_MOUSE;  O77564, FOLH1_PIG  ;
DR   P70627, FOLH1_RAT  ;  Q9M1S8, GCP2_ARATH ;  Q5WN23, GCP2_CAEBR ;
DR   P91406, GCP2_CAEEL ;  Q9Y3Q0, NALD2_HUMAN;  Q9CZR2, NALD2_MOUSE;
DR   Q9UQQ1, NALDL_HUMAN;  Q7M758, NALDL_MOUSE;  O54697, NALDL_RAT  ;
//
ID   3.4.17.22
DE   Metallocarboxypeptidase D.
AN   Carboxypeptidase D.
CA   Releases C-terminal Arg and Lys from polypeptides.
CF   Zinc.
CC   -!- Activated by cobalt.
CC   -!- Inhibited by guanidinoethylmercaptosuccinic acid.
CC   -!- Belongs to peptidase family M14.
DR   Q90240, CBPD_ANAPL ;  P42787, CBPD_DROME ;  O75976, CBPD_HUMAN ;
DR   P83852, CBPD_LOPSP ;  O89001, CBPD_MOUSE ;  Q9JHW1, CBPD_RAT   ;
//
ID   3.4.17.23
DE   Angiotensin-converting enzyme 2.
AN   ACE2.
AN   Angiotensin converting enzyme 2.
AN   Angiotensin converting enzyme-2.
CA   Angiotensin II + H(2)O = angiotensin-(1-7) + L-phenylalanine.
CC   -!- A transmembrane glycoprotein with an extracellular catalytic domain.
CC   -!- Angiotensin-converting enzyme 2 functions as a carboxypeptidase,
CC       cleaving a single C-terminal residue from a distinct range of
CC       substrates.
CC   -!- Catalytic efficiency is 400-fold higher with angiotensin II (1-8) as
CC       a substrate than with angiotensin I (1-10).
CC   -!- Angiotensin-converting enzyme 2 also efficiently hydrolyzes des-
CC       Arg(9)-bradykinin, but it does not hydrolyze bradykinin.
CC   -!- Belongs to peptidase family M2.
PR   PROSITE; PDOC00129;
DR   Q58DD0, ACE2_BOVIN ;  Q56H28, ACE2_FELCA ;  Q9BYF1, ACE2_HUMAN ;
DR   Q8R0I0, ACE2_MOUSE ;  Q56NL1, ACE2_PAGLA ;  Q5RFN1, ACE2_PONAB ;
DR   Q5EGZ1, ACE2_RAT   ;
//
ID   3.4.18.1
DE   Cathepsin X.
AN   Acid carboxypeptidase.
AN   Cathepsin B(2).
AN   Cathepsin IV.
AN   Cathepsin Z.
AN   Cysteine-type carboxypeptidase.
AN   Lysosomal carboxypeptidase B.
CA   Release of C-terminal amino acid residues with broad specificity,
CA   but lacks action on C-terminal proline. Shows weak endopeptidase
CA   activity.
CC   -!- Deamidates Z-Arg-NH(2), but shows no action on the arylamide
CC       derivatives.
CC   -!- Inhibited by thiol-blocking reagents.
CC   -!- Belongs to peptidase family C1.
DR   P05689, CATZ_BOVIN ;  Q9UBR2, CATZ_HUMAN ;  Q9WUU7, CATZ_MOUSE ;
DR   Q9R1T3, CATZ_RAT   ;
//
ID   3.4.19.1
DE   Acylaminoacyl-peptidase.
AN   Acylamino-acid-releasing enzyme.
AN   N-acylpeptide hydrolase.
CA   Cleavage of an N-acetyl or N-formyl amino acid from the N-terminus of a
CA   polypeptide.
CC   -!- Best if P1 = Ser, Ala, Met; poor if P1 = Gly, Tyr, Asp, Asn or Pro.
CC   -!- Group of similar enzymes liberating N-acetyl or N-formyl amino acid
CC       from proteins and peptides.
CC   -!- Active at neutral pH.
CC   -!- Several variants of this enzyme exist; the human erythrocyte enzyme
CC       is relatively specific for removal of N-acetylalanine from peptides.
CC   -!- Display dipeptidyl-peptidase activity on glycyl-peptides, perhaps as
CC       a result of misrecognition of the glycyl residue as an uncharged
CC       N-acyl group.
CC   -!- Inhibited by diisopropyl fluorophosphate.
CC   -!- Belongs to peptidase family S9C.
CC   -!- Formerly EC 3.4.14.3.
PR   PROSITE; PDOC00587;
DR   P80227, ACPH_BOVIN ;  P13798, ACPH_HUMAN ;  P19205, ACPH_PIG   ;
DR   P25154, ACPH_RABIT ;  P13676, ACPH_RAT   ;  Q9YBQ2, APEH_AERPE ;
DR   Q8R146, APEH_MOUSE ;
//
ID   3.4.19.2
DE   Peptidyl-glycinamidase.
AN   Carboxyamidase.
AN   Peptidyl carboxyamidase.
CA   Cleavage of C-terminal glycinamide from polypeptides.
CC   -!- Inactivates vasopressin and oxytocin by splitting off glycinamide.
CC   -!- Also cleaves ester substrates of trypsin and chymotrypsin.
CC   -!- Although glycinamide is by far the preferred leaving group, other
CC       aminoacylamides may also be released, e.g. phenylalaninamide.
CC   -!- The toad skin enzyme is inhibited by diisopropyl fluorophosphate.
CC   -!- Formerly EC 3.4.15.2.
//
ID   3.4.19.3
DE   Pyroglutamyl-peptidase I.
AN   5-oxoprolyl-peptidase.
AN   PYRase.
AN   Pyroglutamyl aminopeptidase.
AN   Pyrrolidone carboxyl peptidase.
AN   Pyrrolidone-carboxylate peptidase.
CA   Release of an N-terminal pyroglutamyl group from a polypeptide,
CA   the second amino acid generally not being Pro.
CC   -!- Removes 5-oxoproline from various penultimate amino acid residues
CC       except L-proline.
CC   -!- Inhibited by thiol-blocking reagents.
CC   -!- Belongs to peptidase family C15.
CC   -!- Formerly EC 3.4.11.8.
PR   PROSITE; PDOC01036;
DR   Q7MAZ1, PCP1_PHOLL ;  Q8XXE9, PCP1_RALSO ;  P65678, PCP1_STRPN ;
DR   P65679, PCP1_STRR6 ;  P58201, PCP1_SULSO ;  Q8RBX8, PCP1_THETN ;
DR   Q7MZ76, PCP2_PHOLL ;  Q8XT56, PCP2_RALSO ;  Q97NG9, PCP2_STRPN ;
DR   P58202, PCP2_SULSO ;  Q8R9J6, PCP2_THETN ;  A8MJA9, PCP_ALKOO  ;
DR   A7Z119, PCP_BACA2  ;  C3P0R7, PCP_BACAA  ;  C3LDV2, PCP_BACAC  ;
DR   A0RFP3, PCP_BACAH  ;  P46107, PCP_BACAM  ;  Q81NT5, PCP_BACAN  ;
DR   B7JDC3, PCP_BACC0  ;  Q735N6, PCP_BACC1  ;  B7IMH6, PCP_BACC2  ;
DR   C1F026, PCP_BACC3  ;  B7H8H3, PCP_BACC4  ;  B7HVU3, PCP_BACC7  ;
DR   A7GQB6, PCP_BACCN  ;  B9J587, PCP_BACCQ  ;  Q81BT3, PCP_BACCR  ;
DR   Q639M5, PCP_BACCZ  ;  Q9K6U4, PCP_BACHD  ;  Q6HH08, PCP_BACHK  ;
DR   Q65FR5, PCP_BACLD  ;  P28618, PCP_BACSU  ;  A9VKA7, PCP_BACWK  ;
DR   C0QXM0, PCP_BRAHW  ;  C0ZCX0, PCP_BREBN  ;  Q7NT84, PCP_CHRVO  ;
DR   A8AJA6, PCP_CITK8  ;  A5CM68, PCP_CLAM3  ;  B2UZU4, PCP_CLOBA  ;
DR   B2TK93, PCP_CLOBB  ;  Q186N3, PCP_CLOD6  ;  Q0TQH4, PCP_CLOP1  ;
DR   Q8XKH1, PCP_CLOPE  ;  Q0ST25, PCP_CLOPS  ;  B5Y5X6, PCP_COPPD  ;
DR   Q0KFE0, PCP_CUPNH  ;  Q477F9, PCP_CUPPJ  ;  B2AG45, PCP_CUPTR  ;
DR   Q9RX25, PCP_DEIRA  ;  A4W870, PCP_ENT38  ;  Q838N8, PCP_ENTFA  ;
DR   Q6D7H1, PCP_ERWCT  ;  B2VBP1, PCP_ERWT9  ;  B7LKQ5, PCP_ESCF3  ;
DR   B0S415, PCP_FINM2  ;  Q8RI83, PCP_FUSNN  ;  Q7NHX6, PCP_GLOVI  ;
DR   B5XZE0, PCP_KLEP3  ;  Q5FMJ2, PCP_LACAC  ;  Q03P20, PCP_LACBA  ;
DR   Q03CK3, PCP_LACC3  ;  B3W7M8, PCP_LACCB  ;  Q040L6, PCP_LACGA  ;
DR   A8YX24, PCP_LACH4  ;  Q74HE9, PCP_LACJO  ;  O87765, PCP_LACLM  ;
DR   B1HUY7, PCP_LYSSC  ;  P0A5R5, PCP_MYCBO  ;  A1KFE2, PCP_MYCBP  ;
DR   C1AJZ7, PCP_MYCBT  ;  B2HP18, PCP_MYCMM  ;  A5TZ46, PCP_MYCTA  ;
DR   P0A5R4, PCP_MYCTU  ;  Q8ENE4, PCP_OCEIH  ;  C6DCC7, PCP_PECCP  ;
DR   P42673, PCP_PSEFL  ;  C3JZR3, PCP_PSEFS  ;  Q9UYQ9, PCP_PYRAB  ;
DR   O73944, PCP_PYRFU  ;  O58321, PCP_PYRHO  ;  Q5JEL5, PCP_PYRKO  ;
DR   A7X782, PCP_STAA1  ;  A6U575, PCP_STAA2  ;  Q2FDH1, PCP_STAA3  ;
DR   Q2FUS6, PCP_STAA8  ;  A5IWB7, PCP_STAA9  ;  Q2YZA2, PCP_STAAB  ;
DR   Q5HCK7, PCP_STAAC  ;  A6QKH8, PCP_STAAE  ;  P65676, PCP_STAAM  ;
DR   P65677, PCP_STAAN  ;  Q6GDB4, PCP_STAAR  ;  Q6G5Y4, PCP_STAAS  ;
DR   A8Z5J1, PCP_STAAT  ;  Q53596, PCP_STAAU  ;  Q8NUH2, PCP_STAAW  ;
DR   B9DND6, PCP_STACT  ;  Q4L9S3, PCP_STAHJ  ;  Q4A002, PCP_STAS1  ;
DR   Q9RL48, PCP_STRCO  ;  P68896, PCP_STRP1  ;  Q04L55, PCP_STRP2  ;
DR   P0DC94, PCP_STRP3  ;  Q5XDD4, PCP_STRP6  ;  C1C6J3, PCP_STRP7  ;
DR   Q8P243, PCP_STRP8  ;  Q1JD20, PCP_STRPB  ;  Q1JMZ5, PCP_STRPC  ;
DR   Q1JI40, PCP_STRPD  ;  Q1J7Y1, PCP_STRPF  ;  A2RFZ5, PCP_STRPG  ;
DR   B1IB28, PCP_STRPI  ;  Q48UT7, PCP_STRPM  ;  P0DC95, PCP_STRPQ  ;
DR   B5XK96, PCP_STRPZ  ;  A4W0R4, PCP_STRS2  ;  A4VUH1, PCP_STRSY  ;
DR   C3N2L8, PCP_SULIA  ;  C4KEG7, PCP_SULIK  ;  C3MP49, PCP_SULIL  ;
DR   C3NL04, PCP_SULIN  ;  C3NAL6, PCP_SULIY  ;  B7IEE2, PCP_THEAB  ;
DR   O07883, PCP_THELI  ;  A6LL24, PCP_THEM4  ;  B6YUJ5, PCP_THEON  ;
DR   B0K8Z7, PCP_THEP3  ;  B0K0D9, PCP_THEPX  ;  Q73RB6, PCP_TREDE  ;
DR   Q5E531, PCP_VIBF1  ;  B5FEA5, PCP_VIBFM  ;  A7N3R7, PCP_VIBHB  ;
DR   Q87IL9, PCP_VIBPA  ;  Q8D4N5, PCP_VIBVU  ;  Q7MG84, PCP_VIBVY  ;
DR   A1JR34, PCP_YERE8  ;  A7FFS3, PCP_YERP3  ;  Q1C571, PCP_YERPA  ;
DR   B2KA64, PCP_YERPB  ;  Q8ZD86, PCP_YERPE  ;  A9R3Y5, PCP_YERPG  ;
DR   Q1CKF9, PCP_YERPN  ;  A4TKZ3, PCP_YERPP  ;  Q667T6, PCP_YERPS  ;
DR   B1JRB0, PCP_YERPY  ;  Q9NXJ5, PGPI_HUMAN ;  Q9ESW8, PGPI_MOUSE ;
DR   Q76IC5, PGPI_RAT   ;
//
ID   3.4.19.4
DE   Deleted entry.
//
ID   3.4.19.5
DE   Beta-aspartyl-peptidase.
CA   Cleavage of a beta-linked Asp residue from the N-terminus of a
CA   polypeptide.
CC   -!- Other isopeptide bonds, e.g. gamma-glutamyl and beta-alanyl, are not
CC       hydrolyzed.
CC   -!- Formerly EC 3.4.13.10.
DR   Q54WW4, ASGX_DICDI ;  Q8YQB1, ASGX_NOSS1 ;  P74383, ASGX_SYNY3 ;
DR   P50287, ASPG1_ARATH;  Q8GXG1, ASPG2_ARATH;  Q56W64, ASPG3_ARATH;
DR   O65268, ASPG4_ARATH;  P50288, ASPG_LUPAL ;  P30364, ASPG_LUPAN ;
DR   P30362, ASPG_LUPAR ;  Q9ZSD6, ASPG_LUPLU ;  P37595, IAAA_ECOLI ;
DR   Q7CQV5, IAAA_SALTY ;
//
ID   3.4.19.6
DE   Pyroglutamyl-peptidase II.
AN   PAP-II.
AN   Pyroglutamyl aminopeptidase II.
AN   Thyroliberinase.
AN   Thyrotropin-releasing hormone degrading ectoenzyme.
AN   TRH-DE.
AN   TRH-degrading ectoenzyme.
AN   TRH-specific aminopeptidase.
CA   Release of the N-terminal pyroglutamyl group from pGlu-|-His-Xaa
CA   tripeptides and pGlu-|-His-Xaa-Gly tetrapeptides.
CF   Zinc.
CC   -!- Highly specific for thyrotropin releasing hormone (pyroglutamyl-
CC       histidyl-prolylamide).
CC   -!- Will not cleave the pyroglutamyl-histidyl bond of luteinizing hormone
CC       releasing hormone.
CC   -!- Found in serum and brain.
CC   -!- Inhibited by metal chelators.
CC   -!- Belongs to peptidase family M1.
PR   PROSITE; PDOC00129;
DR   Q9UKU6, TRHDE_HUMAN;  Q8K093, TRHDE_MOUSE;  Q10836, TRHDE_RAT  ;
//
ID   3.4.19.7
DE   N-formylmethionyl-peptidase.
AN   (fMet)-releasing enzyme.
CA   Release of an N-terminal, formyl-methionyl residue from a polypeptide.
CC   -!- Highly specific for N-formylmethionyl-peptides.
CC   -!- Will not cleave methionyl peptides or N-formyl derivatives of amino
CC       acids other than methionine.
CC   -!- Isolated from liver.
CC   -!- Inhibited by heavy metals and activated by chloride.
//
ID   3.4.19.8
DE   Transferred entry: 3.4.17.21.
//
ID   3.4.19.9
DE   Gamma-glutamyl hydrolase.
AN   Carboxypeptidase G.
AN   Conjugase.
AN   Folate conjugase.
AN   Gamma-Glu-X carboxypeptidase.
AN   Lysosomal gamma-glutamyl carboxypeptidase.
AN   Pteroyl-poly-alpha-glutamate hydrolase.
CA   Hydrolysis of a gamma-glutamyl bond.
CC   -!- A lysosomal or secreted, thiol-dependent peptidase, most active at
CC       acidic pH.
CC   -!- Commonly studied with folylpoly-gamma-glutamate as substrate, with
CC       which the initial cleavage may release glutamate or poly-gamma-
CC       glutamate of two or more residues, according to the species of origin
CC       of the enzyme.
CC   -!- Final products are pteroyl-alpha-glutamate (folic acid) and free
CC       glutamate.
CC   -!- Highly specific for the gamma-glutamyl bond, but not for the
CC       C-terminal amino acid (leaving group).
CC   -!- Action on gamma-glutamyl bonds is independent of an N-terminal
CC       pteroyl moiety, but it is not known whether an N-terminal gamma-Glu
CC       residue can be hydrolyzed.
CC   -!- Belongs to peptidase family C26.
CC   -!- Formerly EC 3.4.12.10 and EC 3.4.22.12.
PR   PROSITE; PDOC51275;
DR   Q54LN4, GGHA_DICDI ;  Q54HL4, GGHB_DICDI ;  O65355, GGH_ARATH  ;
DR   A7YWG4, GGH_BOVIN  ;  Q92820, GGH_HUMAN  ;  Q9Z0L8, GGH_MOUSE  ;
DR   Q62867, GGH_RAT    ;  P93164, GGH_SOYBN  ;
//
ID   3.4.19.10
DE   Transferred entry: 3.5.1.28.
//
ID   3.4.19.11
DE   Gamma-D-glutamyl-meso-diaminopimelate peptidase.
AN   Endopeptidase I.
AN   Gamma-D-glutamyl-L-diamino acid endopeptidase I.
AN   Gamma-D-glutamyl-meso-diaminopimelate peptidase I.
CA   Hydrolysis of gamma-D-glutamyl bonds to the L-terminus (position 7) of
CA   meso-diaminopimelic acid (meso-A(2)pm) in 7-(L-Ala-gamma-D-Glu)-meso-
CA   A(2)pm and 7-(L-Ala-gamma-D-Glu)-7-(D-Ala)-meso-A(2)pm. It is required
CA   that the D-terminal amino and carboxy groups of meso-A(2)pm are
CA   unsubstituted.
CC   -!- Metallopeptidase from Bacillus sphaericus, the substrates being
CC       components of the bacterial spore wall.
CC   -!- Belongs to peptidase family M14.
DR   O31852, CWLS_BACSU ;  Q03415, ENP1_LYSSH ;
//
ID   3.4.19.12
DE   Ubiquitinyl hydrolase 1.
AN   Ubiquitin C-terminal hydrolase.
AN   Ubiquitin carboxyl-terminal hydrolase.
AN   Ubiquitin thiolesterase.
CA   Thiol-dependent hydrolysis of ester, thioester, amide, peptide and
CA   isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue
CA   protein attached to proteins as an intracellular targeting signal).
CC   -!- Links to polypeptides smaller than 60 residues are hydrolyzed more
CC       readily than those to larger polypeptides.
CC   -!- Isoforms exist with quantitatively different specificities among the
CC       best known being UCH-L1 and UCH-L3, major proteins of the brain of
CC       mammals.
CC   -!- Inhibited by ubiquitin aldehyde (in which Gly76 is replaced by
CC       aminoacetaldehyde).
CC   -!- Belongs to peptidase family C12.
PR   PROSITE; PDOC00127;
DR   Q9M391, ATX3H_ARATH;  Q9H3M9, ATX3L_HUMAN;  Q60XN1, ATX3_CAEBR ;
DR   O17850, ATX3_CAEEL ;  Q9W689, ATX3_CHICK ;  P54252, ATX3_HUMAN ;
DR   Q9CVD2, ATX3_MOUSE ;  Q8LQ36, ATX3_ORYSJ ;  O35815, ATX3_RAT   ;
DR   A2VDM8, BAP1_BOVIN ;  C4A0D9, BAP1_BRAFL ;  Q5F3N6, BAP1_CHICK ;
DR   A1L2G3, BAP1_DANRE ;  Q92560, BAP1_HUMAN ;  Q99PU7, BAP1_MOUSE ;
DR   D3ZHS6, BAP1_RAT   ;  Q52L14, BAP1_XENLA ;  Q66JB6, BAP1_XENTR ;
DR   Q17N72, CALYP_AEDAE;  B0W2R4, CALYP_CULQU;  B3MIV9, CALYP_DROAN;
DR   B3NPV7, CALYP_DROER;  B4JW98, CALYP_DROGR;  Q7K5N4, CALYP_DROME;
DR   B4KT51, CALYP_DROMO;  B4GAM2, CALYP_DROPE;  Q291J4, CALYP_DROPS;
DR   B4HST0, CALYP_DROSE;  B4QHH0, CALYP_DROSI;  B4LQ24, CALYP_DROVI;
DR   B4P6P6, CALYP_DROYA;  A1CIL1, CREB_ASPCL ;  B0Y4P5, CREB_ASPFC ;
DR   B8NSV5, CREB_ASPFN ;  Q4WQI1, CREB_ASPFU ;  A2Q9N1, CREB_ASPNC ;
DR   Q2UUG8, CREB_ASPOR ;  Q0CT11, CREB_ASPTN ;  Q96V54, CREB_EMENI ;
DR   A1CW53, CREB_NEOFI ;  Q1RMU2, CYLD_BOVIN ;  Q9NQC7, CYLD_HUMAN ;
DR   Q80TQ2, CYLD_MOUSE ;  Q5RED8, CYLD_PONAB ;  Q66H62, CYLD_RAT   ;
DR   Q1HVH9, DEN_EBVA8  ;  P03186, DEN_EBVB9  ;  Q3KSU8, DEN_EBVG   ;
DR   P28955, DEN_EHV1B  ;  Q9E6N3, DEN_GAHVM  ;  P16785, DEN_HCMVA  ;
DR   D5LX59, DEN_HCMVT  ;  P10220, DEN_HHV11  ;  P89459, DEN_HHV2H  ;
DR   P52340, DEN_HHV6U  ;  Q9QJ37, DEN_HHV6Z  ;  Q2HR64, DEN_HHV8P  ;
DR   O41965, DEN_MHV68  ;  A8E1C4, DEN_MUHVK  ;  Q6UDJ5, DEN_PSHV1  ;
DR   P09278, DEN_VZVD   ;  Q4JQX9, DEN_VZVO   ;  P55824, FAF_DROME  ;
DR   Q5EAE5, JOS1_BOVIN ;  Q15040, JOS1_HUMAN ;  Q9DBJ6, JOS1_MOUSE ;
DR   Q5R739, JOS1_PONAB ;  Q5BJY4, JOS1_RAT   ;  Q8TAC2, JOS2_HUMAN ;
DR   Q9CR30, JOS2_MOUSE ;  O82391, JOSL_ARATH ;  Q9W422, JOSL_DROME ;
DR   Q6TQR6, L_CCHFI    ;  Q66431, L_DUGBA    ;  Q9VVR1, NOT_DROME  ;
DR   Q05B57, OTU1_BOVIN ;  Q5F3A6, OTU1_CHICK ;  Q567B1, OTU1_DANRE ;
DR   Q55BI3, OTU1_DICDI ;  Q9VRJ9, OTU1_DROME ;  Q29FC9, OTU1_DROPS ;
DR   Q5VVQ6, OTU1_HUMAN ;  Q8CB27, OTU1_MOUSE ;  Q32Q05, OTU1_RAT   ;
DR   O13974, OTU1_SCHPO ;  Q0IH43, OTU1_XENLA ;  P43558, OTU1_YEAST ;
DR   Q08BW0, OTU5A_DANRE;  Q7ZX21, OTU5A_XENLA;  Q640H3, OTU5B_XENLA;
DR   Q8TE49, OTU7A_HUMAN;  Q8R554, OTU7A_MOUSE;  Q6GQQ9, OTU7B_HUMAN;
DR   Q96FW1, OTUB1_HUMAN;  Q7TQI3, OTUB1_MOUSE;  B2RYG6, OTUB1_RAT  ;
DR   Q96DC9, OTUB2_HUMAN;  Q9CQX0, OTUB2_MOUSE;  Q8LG98, OTUBL_ARATH;
DR   A8XDJ2, OTUBL_CAEBR;  Q9XVR6, OTUBL_CAEEL;  Q9VL00, OTUBL_DROME;
DR   Q96G74, OTUD5_HUMAN;  Q3U2S4, OTUD5_MOUSE;  Q2YDU3, OTUD5_RAT  ;
DR   Q6GL44, OTUD5_XENTR;  P0C6W1, R1AB_BC133 ;  P0C6V9, R1AB_BC279 ;
DR   P0C6W0, R1AB_BC512 ;  P0C6W2, R1AB_BCHK3 ;  P0C6W3, R1AB_BCHK4 ;
DR   P0C6W4, R1AB_BCHK5 ;  P0C6W5, R1AB_BCHK9 ;  P0C6W6, R1AB_BCRP3 ;
DR   P0C6W7, R1AB_CVBEN ;  P0C6W8, R1AB_CVBLU ;  P0C6W9, R1AB_CVBM  ;
DR   P0C6X0, R1AB_CVBQ  ;  P0C6X1, R1AB_CVH22 ;  P0C6X2, R1AB_CVHN1 ;
DR   P0C6X3, R1AB_CVHN2 ;  P0C6X4, R1AB_CVHN5 ;  P0C6X5, R1AB_CVHNL ;
DR   P0C6X6, R1AB_CVHOC ;  P0C6X7, R1AB_CVHSA ;  P0C6X8, R1AB_CVM2  ;
DR   P0C6X9, R1AB_CVMA5 ;  P0C6Y0, R1AB_CVMJH ;  P0C6Y5, R1AB_CVPPU ;
DR   Q98VG9, R1AB_FIPV  ;  P0C6Y4, R1AB_PEDV7 ;  P0C6F7, R1A_BC133  ;
DR   P0C6F5, R1A_BC279  ;  P0C6F6, R1A_BC512  ;  P0C6F8, R1A_BCHK3  ;
DR   P0C6T4, R1A_BCHK4  ;  P0C6T5, R1A_BCHK5  ;  P0C6T6, R1A_BCHK9  ;
DR   P0C6T7, R1A_BCRP3  ;  P0C6T8, R1A_CVBEN  ;  P0C6T9, R1A_CVBLU  ;
DR   P0C6U0, R1A_CVBM   ;  P0C6U1, R1A_CVBQ   ;  P0C6U2, R1A_CVH22  ;
DR   P0C6U3, R1A_CVHN1  ;  P0C6U4, R1A_CVHN2  ;  P0C6U5, R1A_CVHN5  ;
DR   P0C6U6, R1A_CVHNL  ;  P0C6U7, R1A_CVHOC  ;  P0C6U8, R1A_CVHSA  ;
DR   P0C6U9, R1A_CVM2   ;  P0C6V0, R1A_CVMA5  ;  P0C6V1, R1A_CVMJH  ;
DR   P0C6V2, R1A_CVPPU  ;  P0C6V6, R1A_PEDV7  ;  P19811, RPOA_EAVBU ;
DR   Q9YN02, RPOA_PRRS1 ;  Q8B912, RPOA_PRRSB ;  Q04561, RPOA_PRRSL ;
DR   Q9WJB2, RPOA_PRRSR ;  A0MD28, RPOA_PRRSS ;  P52362, TEGU_HHV7J ;
DR   P21580, TNAP3_HUMAN;  Q4R8W3, TNAP3_MACFA;  Q60769, TNAP3_MOUSE;
DR   Q9VH90, TRBID_DROME;  Q7RTZ2, U17L1_HUMAN;  Q6R6M4, U17L2_HUMAN;
DR   Q7M764, U17L2_MOUSE;  A6NCW0, U17L3_HUMAN;  A8MUK1, U17L5_HUMAN;
DR   Q6QN14, U17L6_HUMAN;  Q2NL57, UB10A_XENLA;  Q7ZXR7, UB10B_XENLA;
DR   Q52KZ6, UB12A_XENLA;  Q5M981, UB12B_XENLA;  Q6GNI6, UB22A_XENLA;
DR   Q6DCJ1, UB22B_XENLA;  Q09444, UBH4_CAEEL ;  P35127, UBL1_YEAST ;
DR   Q10171, UBLH1_SCHPO;  Q9UUB6, UBLH2_SCHPO;  Q9ZSB5, UBP10_ARATH;
DR   A5PJS6, UBP10_BOVIN;  Q5ZJN4, UBP10_CHICK;  Q14694, UBP10_HUMAN;
DR   P52479, UBP10_MOUSE;  Q3KR59, UBP10_RAT  ;  Q6DIJ4, UBP10_XENTR;
DR   P53874, UBP10_YEAST;  Q9MAQ3, UBP11_ARATH;  Q01988, UBP11_CANFA;
DR   P51784, UBP11_HUMAN;  Q99K46, UBP11_MOUSE;  Q9UUD6, UBP11_SCHPO;
DR   P36026, UBP11_YEAST;  Q9FPT1, UBP12_ARATH;  A5D9H7, UBP12_BOVIN;
DR   A4FUN7, UBP12_DANRE;  O75317, UBP12_HUMAN;  Q9D9M2, UBP12_MOUSE;
DR   C0HB46, UBP12_SALSA;  O60079, UBP12_SCHPO;  P39538, UBP12_YEAST;
DR   Q84WU2, UBP13_ARATH;  Q92995, UBP13_HUMAN;  P38187, UBP13_YEAST;
DR   Q8L6Y1, UBP14_ARATH;  Q0IIF7, UBP14_BOVIN;  Q17361, UBP14_CAEEL;
DR   P54578, UBP14_HUMAN;  Q9JMA1, UBP14_MOUSE;  P60051, UBP14_PANTR;
DR   P40826, UBP14_RABIT;  Q11119, UBP14_SCHPO;  P38237, UBP14_YEAST;
DR   Q9FPS9, UBP15_ARATH;  Q9Y4E8, UBP15_HUMAN;  Q8R5H1, UBP15_MOUSE;
DR   P50101, UBP15_YEAST;  Q9SB51, UBP16_ARATH;  Q08DA3, UBP16_BOVIN;
DR   A8HAL1, UBP16_DANRE;  P0CAQ1, UBP16_EMENI;  Q9Y5T5, UBP16_HUMAN;
DR   Q4R6X7, UBP16_MACFA;  Q99LG0, UBP16_MOUSE;  Q2KJ09, UBP16_RAT  ;
DR   O74442, UBP16_SCHPO;  Q6PAW2, UBP16_XENLA;  Q0VA64, UBP16_XENTR;
DR   Q02863, UBP16_YEAST;  Q9FKP5, UBP17_ARATH;  Q0WX57, UBP17_HUMAN;
DR   Q67XW5, UBP18_ARATH;  Q9SJA1, UBP19_ARATH;  O94966, UBP19_HUMAN;
DR   Q3UJD6, UBP19_MOUSE;  Q6J1Y9, UBP19_RAT  ;  Q9FPT5, UBP1_ARATH ;
DR   Q29RP1, UBP1_BOVIN ;  O94782, UBP1_HUMAN ;  Q8BJQ2, UBP1_MOUSE ;
DR   Q569C3, UBP1_RAT   ;  Q9USM5, UBP1_SCHPO ;  P25037, UBP1_YEAST ;
DR   Q9FPS7, UBP20_ARATH;  A7Z056, UBP20_BOVIN;  A5PN09, UBP20_DANRE;
DR   Q9Y2K6, UBP20_HUMAN;  Q8C6M1, UBP20_MOUSE;  Q5R5Z6, UBP20_PONAB;
DR   B1WBD7, UBP20_XENLA;  A0JM59, UBP20_XENTR;  Q9FIQ1, UBP21_ARATH;
DR   Q2KJ72, UBP21_BOVIN;  Q9UK80, UBP21_HUMAN;  Q9QZL6, UBP21_MOUSE;
DR   B2GUX4, UBP21_RAT  ;  Q9UTT1, UBP21_SCHPO;  Q9LEW0, UBP22_ARATH;
DR   P0C8Z3, UBP22_BOVIN;  A6H8I0, UBP22_DANRE;  Q9UPT9, UBP22_HUMAN;
DR   Q5DU02, UBP22_MOUSE;  Q9FPS4, UBP23_ARATH;  Q9FPS3, UBP24_ARATH;
DR   Q9UPU5, UBP24_HUMAN;  B1AY13, UBP24_MOUSE;  Q9FPS2, UBP25_ARATH;
DR   Q9UHP3, UBP25_HUMAN;  P57080, UBP25_MOUSE;  Q9SCJ9, UBP26_ARATH;
DR   Q9BXU7, UBP26_HUMAN;  Q99MX1, UBP26_MOUSE;  A2XDG4, UBP26_ORYSI;
DR   A3AF13, UBP26_ORYSJ;  Q9FPS0, UBP27_ARATH;  A6NNY8, UBP27_HUMAN;
DR   Q8CEG8, UBP27_MOUSE;  Q5ZID5, UBP28_CHICK;  Q96RU2, UBP28_HUMAN;
DR   Q5I043, UBP28_MOUSE;  D3ZJ96, UBP28_RAT  ;  Q9HBJ7, UBP29_HUMAN;
DR   Q9ES63, UBP29_MOUSE;  Q8W4N3, UBP2_ARATH ;  Q2KHV7, UBP2_BOVIN ;
DR   O57429, UBP2_CHICK ;  O75604, UBP2_HUMAN ;  O42726, UBP2_KLULA ;
DR   O88623, UBP2_MOUSE ;  Q5U349, UBP2_RAT   ;  Q9P3U0, UBP2_SCHPO ;
DR   Q01476, UBP2_YEAST ;  A2BGT0, UBP30_DANRE;  Q70CQ3, UBP30_HUMAN;
DR   Q3UN04, UBP30_MOUSE;  A4QNN3, UBP30_XENTR;  Q70CQ4, UBP31_HUMAN;
DR   Q8NFA0, UBP32_HUMAN;  A6QNM7, UBP33_BOVIN;  A5PMR2, UBP33_DANRE;
DR   Q8TEY7, UBP33_HUMAN;  Q8R5K2, UBP33_MOUSE;  Q5REG5, UBP33_PONAB;
DR   Q28CN3, UBP33_XENTR;  Q70CQ2, UBP34_HUMAN;  Q6ZQ93, UBP34_MOUSE;
DR   Q9P2H5, UBP35_HUMAN;  B3M3M6, UBP36_DROAN;  B3NC86, UBP36_DROER;
DR   B4IXE0, UBP36_DROGR;  Q9VRP5, UBP36_DROME;  B4KXJ5, UBP36_DROMO;
DR   Q2LZB1, UBP36_DROPS;  B4HUI5, UBP36_DROSE;  B4QIS3, UBP36_DROSI;
DR   B4LG38, UBP36_DROVI;  B4MLR8, UBP36_DROWI;  B4PIW8, UBP36_DROYA;
DR   Q9P275, UBP36_HUMAN;  B1AQJ2, UBP36_MOUSE;  F1N5V1, UBP37_BOVIN;
DR   E2RK09, UBP37_CANFA;  E1C213, UBP37_CHICK;  E7F6T8, UBP37_DANRE;
DR   Q86T82, UBP37_HUMAN;  Q8C0R0, UBP37_MOUSE;  F1SRY5, UBP37_PIG  ;
DR   Q8NB14, UBP38_HUMAN;  Q8BW70, UBP38_MOUSE;  O24454, UBP3_ARATH ;
DR   Q9Y6I4, UBP3_HUMAN ;  Q91W36, UBP3_MOUSE ;  O94269, UBP3_SCHPO ;
DR   Q01477, UBP3_YEAST ;  Q9NVE5, UBP40_HUMAN;  Q8BWR4, UBP40_MOUSE;
DR   Q3LFD5, UBP41_HUMAN;  E1B9W9, UBP42_BOVIN;  Q9H9J4, UBP42_HUMAN;
DR   B2RQC2, UBP42_MOUSE;  D3ZU96, UBP42_RAT  ;  Q70EL4, UBP43_HUMAN;
DR   Q8BUM9, UBP43_MOUSE;  D2HBJ8, UBP44_AILME;  Q7ZUM8, UBP44_DANRE;
DR   Q9H0E7, UBP44_HUMAN;  Q0V9G5, UBP44_XENTR;  Q70EL2, UBP45_HUMAN;
DR   Q8K387, UBP45_MOUSE;  A5WWB0, UBP46_DANRE;  P62068, UBP46_HUMAN;
DR   P62069, UBP46_MOUSE;  Q5RBQ4, UBP46_PONAB;  E1C1R4, UBP47_CHICK;
DR   Q96K76, UBP47_HUMAN;  Q8BY87, UBP47_MOUSE;  Q5U252, UBP47_XENLA;
DR   A1A5G2, UBP47_XENTR;  Q5ZM45, UBP48_CHICK;  Q86UV5, UBP48_HUMAN;
DR   Q3V0C5, UBP48_MOUSE;  Q76LT8, UBP48_RAT  ;  Q70CQ1, UBP49_HUMAN;
DR   Q6P9L4, UBP49_MOUSE;  Q8LAM0, UBP4_ARATH ;  Q754R5, UBP4_ASHGO ;
DR   A6QR55, UBP4_BOVIN ;  Q6FQF0, UBP4_CANGA ;  Q13107, UBP4_HUMAN ;
DR   Q9HFS7, UBP4_KLULA ;  P35123, UBP4_MOUSE ;  Q5RCD3, UBP4_PONAB ;
DR   B2GUZ1, UBP4_RAT   ;  O60139, UBP4_SCHPO ;  A7TGY3, UBP4_VANPO ;
DR   B3LGK1, UBP4_YEAS1 ;  A6ZY34, UBP4_YEAS7 ;  P32571, UBP4_YEAST ;
DR   Q4R6D3, UBP50_MACFA;  Q6P8X6, UBP50_MOUSE;  Q70EK9, UBP51_HUMAN;
DR   O22207, UBP5_ARATH ;  P45974, UBP5_HUMAN ;  P56399, UBP5_MOUSE ;
DR   Q5R407, UBP5_PONAB ;  Q09879, UBP5_SCHPO ;  P39944, UBP5_YEAST ;
DR   Q949Y0, UBP6_ARATH ;  P35125, UBP6_HUMAN ;  Q92353, UBP6_SCHPO ;
DR   P43593, UBP6_YEAST ;  Q84WC6, UBP7_ARATH ;  Q60MK8, UBP7_CAEBR ;
DR   Q7JKC3, UBP7_CAEEL ;  Q6U7I1, UBP7_CHICK ;  Q9VYQ8, UBP7_DROME ;
DR   Q93009, UBP7_HUMAN ;  Q6A4J8, UBP7_MOUSE ;  Q4VSI4, UBP7_RAT   ;
DR   Q9P7S5, UBP7_SCHPO ;  P40453, UBP7_YEAST ;  Q9C585, UBP8_ARATH ;
DR   P40818, UBP8_HUMAN ;  Q80U87, UBP8_MOUSE ;  Q09738, UBP8_SCHPO ;
DR   P50102, UBP8_YEAST ;  Q93Y01, UBP9_ARATH ;  Q9P7V9, UBP9_SCHPO ;
DR   P39967, UBP9_YEAST ;  P54201, UBPA_DICDI ;  O96612, UBPB_DICDI ;
DR   Q24574, UBPE_DROME ;  Q5UQR3, UBPL1_MIMIV;  Q5UPW7, UBPL2_MIMIV;
DR   Q61068, UBPW_MOUSE ;  P34547, UBPX_CAEEL ;  Q09931, UBPY_CAEEL ;
DR   P23356, UCHL1_BOVIN;  Q9GM50, UCHL1_HORSE;  P09936, UCHL1_HUMAN;
DR   Q60HC8, UCHL1_MACFA;  P50103, UCHL1_MONDO;  Q9R0P9, UCHL1_MOUSE;
DR   Q6SEG5, UCHL1_PIG  ;  Q00981, UCHL1_RAT  ;  Q2TBG8, UCHL3_BOVIN;
DR   P15374, UCHL3_HUMAN;  Q9JKB1, UCHL3_MOUSE;  Q06AB3, UCHL3_PIG  ;
DR   Q91Y78, UCHL3_RAT  ;  P58321, UCHL4_MOUSE;  Q9XSJ0, UCHL5_BOVIN;
DR   Q54N38, UCHL5_DICDI;  Q9Y5K5, UCHL5_HUMAN;  Q9WUP7, UCHL5_MOUSE;
DR   Q06AT3, UCHL5_PIG  ;  O01391, UCHL_APLCA ;  Q54T48, UCHL_DICDI ;
DR   P35122, UCHL_DROME ;  Q6NTR6, UP44A_XENLA;  Q5XGZ2, UP44B_XENLA;
DR   Q93008, USP9X_HUMAN;  P70398, USP9X_MOUSE;  O00507, USP9Y_HUMAN;
DR   Q196X6, VF232_IIV3 ;  Q91FU0, VF232_IIV6 ;  P22856, VL96_IRV1  ;
DR   A6QP16, ZRAN1_BOVIN;  Q9UGI0, ZRAN1_HUMAN;  Q7M760, ZRAN1_MOUSE;
DR   B1H2Q2, ZRAN1_XENTR;  Q5U595, ZRN1A_XENLA;  A0JMQ9, ZRN1B_DANRE;
DR   Q6NUB7, ZRN1B_XENLA;
//
ID   3.4.21.1
DE   Chymotrypsin.
AN   Alpha-chymotrypsin.
AN   Chymotrypsin A.
AN   Chymotrypsin B.
CA   Preferential cleavage: Tyr-|-Xaa, Trp-|-Xaa, Phe-|-Xaa, Leu-|-Xaa.
CC   -!- Belongs to peptidase family S1.
CC   -!- Formerly EC 3.4.4.5 and EC 3.4.4.6.
PR   PROSITE; PDOC00124;
DR   Q27289, CTR1_ANOGA ;  P84310, CTR1_LUMTE ;  Q7SIG2, CTR1_SOLIN ;
DR   Q17025, CTR2_ANOGA ;  P04813, CTR2_CANFA ;  P00769, CTR2_VESCR ;
DR   P00768, CTR2_VESOR ;  P00766, CTRA_BOVIN ;  P47796, CTRA_GADMO ;
DR   P17538, CTRB1_HUMAN;  Q00871, CTRB1_LITVA;  Q9CR35, CTRB1_MOUSE;
DR   P07338, CTRB1_RAT  ;  Q6GPI1, CTRB2_HUMAN;  P36178, CTRB2_LITVA;
DR   P00767, CTRB_BOVIN ;  P80646, CTRB_GADMO ;  P35002, CTRP_PENMO ;
DR   O97398, CTR_PHACE  ;
//
ID   3.4.21.2
DE   Chymotrypsin C.
AN   Caldecrin.
CA   Preferential cleavage: Leu-|-Xaa, Tyr-|-Xaa, Phe-|-Xaa, Met-|-Xaa,
CA   Trp-|-Xaa, Gln-|-Xaa, Asn-|-Xaa.
CC   -!- Reacts more readily with Tos-Leu-CH(2)Cl than Tos-Phe-CH(2)Cl,
CC       in contrast to chymotrypsin.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   Q7M3E1, CTRC_BOVIN ;  Q99895, CTRC_HUMAN ;  Q3SYP2, CTRC_MOUSE ;
DR   P55091, CTRC_RAT   ;
//
ID   3.4.21.3
DE   Metridin.
AN   Metridium proteinase A.
AN   Sea anemone protease A.
CA   Preferential cleavage: Tyr-|-Xaa, Phe-|-Xaa, Leu-|-Xaa; little action on
CA   Trp-|-Xaa.
CC   -!- Digestive enzyme from the sea anemone Metridium senile.
//
ID   3.4.21.4
DE   Trypsin.
AN   Alpha-trypsin.
AN   Beta-trypsin.
CA   Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
CC   -!- Belongs to peptidase family S1.
CC   -!- Formerly EC 3.4.4.4.
PR   PROSITE; PDOC00124;
DR   Q8IYP2, PRS58_HUMAN;  Q8BW11, PRS58_MOUSE;  Q6IE06, PRS58_RAT  ;
DR   P35035, TRY1_ANOGA ;  P00760, TRY1_BOVIN ;  P06871, TRY1_CANFA ;
DR   Q90627, TRY1_CHICK ;  P16049, TRY1_GADMO ;  P07477, TRY1_HUMAN ;
DR   P00762, TRY1_RAT   ;  P35031, TRY1_SALSA ;  P19799, TRY1_XENLA ;
DR   P35036, TRY2_ANOGA ;  Q29463, TRY2_BOVIN ;  P06872, TRY2_CANFA ;
DR   Q90628, TRY2_CHICK ;  P07478, TRY2_HUMAN ;  P07146, TRY2_MOUSE ;
DR   P00763, TRY2_RAT   ;  P35032, TRY2_SALSA ;  P70059, TRY2_XENLA ;
DR   P29786, TRY3_AEDAE ;  P35037, TRY3_ANOGA ;  Q90629, TRY3_CHICK ;
DR   P35030, TRY3_HUMAN ;  P08426, TRY3_RAT   ;  P35033, TRY3_SALSA ;
DR   P35038, TRY4_ANOGA ;  P12788, TRY4_RAT   ;  P29787, TRY5_AEDAE ;
DR   P35039, TRY5_ANOGA ;  P35040, TRY6_ANOGA ;  Q8NHM4, TRY6_HUMAN ;
DR   P35041, TRY7_ANOGA ;  P35043, TRYA3_LUCCU;  P35044, TRYA4_LUCCU;
DR   P54624, TRYA_DROER ;  P04814, TRYA_DROME ;  P35045, TRYA_MANSE ;
DR   P32821, TRYA_RAT   ;  P54625, TRYB_DROER ;  P35004, TRYB_DROME ;
DR   P35046, TRYB_MANSE ;  P32822, TRYB_RAT   ;  P35047, TRYC_MANSE ;
DR   P54626, TRYDG_DROER;  P42276, TRYDG_DROME;  P54627, TRYE_DROER ;
DR   P35005, TRYE_DROME ;  P52905, TRYI_DROME ;  P83348, TRYP_APIMS ;
DR   P00765, TRYP_ASTFL ;  P35042, TRYP_CHOFU ;  P81071, TRYP_FELCA ;
DR   P35049, TRYP_FUSOX ;  P35050, TRYP_PENMO ;  O97399, TRYP_PHACE ;
DR   P00761, TRYP_PIG   ;  P35034, TRYP_PLEPL ;  P35051, TRYP_PROAT ;
DR   P24664, TRYP_SACER ;  P51588, TRYP_SARBU ;  P35048, TRYP_SIMVI ;
DR   P00764, TRYP_SQUAC ;  P00775, TRYP_STRGR ;  P54628, TRYT_DROER ;
DR   P42278, TRYT_DROME ;  P54629, TRYU_DROER ;  P42279, TRYU_DROME ;
DR   Q91041, TRYX_GADMO ;  P54630, TRYZ_DROER ;  P42280, TRYZ_DROME ;
//
ID   3.4.21.5
DE   Thrombin.
AN   Fibrinogenase.
CA   Selective cleavage of Arg-|-Gly bonds in fibrinogen to form fibrin and
CA   release fibrinopeptides A and B.
CC   -!- More selective than trypsin and plasmin.
CC   -!- Belongs to peptidase family S1.
CC   -!- Formerly EC 3.4.4.13.
PR   PROSITE; PDOC00124;
DR   P00735, THRB_BOVIN ;  P00734, THRB_HUMAN ;  P19221, THRB_MOUSE ;
DR   Q19AZ8, THRB_PIG   ;  Q5R537, THRB_PONAB ;  P18292, THRB_RAT   ;
DR   P84122, THRB_SALSA ;
//
ID   3.4.21.6
DE   Coagulation factor Xa.
AN   Prothrombase.
AN   Prothrombinase.
AN   Stuart factor.
AN   Thrombokinase.
CA   Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin
CA   to form thrombin.
CC   -!- A blood coagulation factor formed from the proenzyme factor X by
CC       limited proteolysis.
CC   -!- Factor X is a glycoprotein composed of a heavy chain and a light
CC       chain, which are generated from a precursor protein by the excision
CC       of the tripeptide RKR and held together by one or more disulfide
CC       bonds.
CC   -!- The activated factor Xa converts prothrombin to thrombin in the
CC       presence of factor Va, Ca(2+) and phospholipids.
CC   -!- Scutelarin (EC 3.4.21.60) has similar specificity, but does not
CC       require factor Va.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   Q1L659, FA101_PSETE;  Q1L658, FA102_PSETE;  P00743, FA10_BOVIN ;
DR   P25155, FA10_CHICK ;  P00742, FA10_HUMAN ;  O88947, FA10_MOUSE ;
DR   O19045, FA10_RABIT ;  Q63207, FA10_RAT   ;  Q4QXT9, FA10_TROCA ;
DR   Q58L95, FAXC_OXYMI ;  Q58L96, FAXC_OXYSU ;  Q56VR3, FAXC_PSETE ;
DR   A6MFK7, FAXD1_DEMVE;  P82807, FAXD1_NOTSC;  A6MFK8, FAXD2_DEMVE;
DR   Q58L94, FAXD2_NOTSC;  P83370, FAXD_HOPST ;  P0CY52, FAXD_NOTAI ;
DR   Q58L93, FAXD_PSEPO ;  B5G6G5, FAXD_RHING ;  P81428, FAXD_TROCA ;
//
ID   3.4.21.7
DE   Plasmin.
AN   Fibrinase.
AN   Fibrinolysin.
CA   Preferential cleavage: Lys-|-Xaa > Arg-|-Xaa; higher selectivity than
CA   trypsin. Converts fibrin into soluble products.
CC   -!- Formed from plasminogen by proteolysis which results in multiple
CC       forms of the active plasmin.
CC   -!- Belongs to peptidase family S1.
CC   -!- Formerly EC 3.4.4.14.
PR   PROSITE; PDOC00124;
DR   P06868, PLMN_BOVIN ;  P80009, PLMN_CANFA ;  Q7M323, PLMN_CAPHI ;
DR   Q29485, PLMN_ERIEU ;  P80010, PLMN_HORSE ;  P00747, PLMN_HUMAN ;
DR   O18783, PLMN_MACEU ;  P12545, PLMN_MACMU ;  P20918, PLMN_MOUSE ;
DR   P33574, PLMN_PETMA ;  P06867, PLMN_PIG   ;  Q5R8X6, PLMN_PONAB ;
DR   Q01177, PLMN_RAT   ;  P81286, PLMN_SHEEP ;  P83169, PLMN_STRCA ;
//
ID   3.4.21.8
DE   Transferred entry: 3.4.21.34 and 3.4.21.35.
//
ID   3.4.21.9
DE   Enteropeptidase.
AN   Enterokinase.
CA   Activation of trypsinogen by selective cleavage of 6-Lys-|-Ile-7 bond.
CC   -!- Activates trypsinogen.
CC   -!- Not inhibited by protein inhibitors of trypsin.
CC   -!- Belongs to peptidase family S1.
CC   -!- Formerly EC 3.4.4.8.
PR   PROSITE; PDOC00124;
PR   PROSITE; PDOC00604;
DR   P98072, ENTK_BOVIN ;  P98073, ENTK_HUMAN ;  P97435, ENTK_MOUSE ;
DR   P98074, ENTK_PIG   ;
//
ID   3.4.21.10
DE   Acrosin.
CA   Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
CC   -!- Inhibited by naturally occurring trypsin inhibitors.
CC   -!- Occurs in spermatozoa.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   P10626, ACRO_CAPHI ;  P10323, ACRO_HUMAN ;  P23578, ACRO_MOUSE ;
DR   P08001, ACRO_PIG   ;  P48038, ACRO_RABIT ;  P29293, ACRO_RAT   ;
DR   Q9GL10, ACRO_SHEEP ;
//
ID   3.4.21.11
DE   Transferred entry: 3.4.21.36 and 3.4.21.37.
//
ID   3.4.21.12
DE   Alpha-lytic endopeptidase.
AN   Alpha-lytic protease.
CA   Preferential cleavage: Ala-|-Xaa, Val-|-Xaa in bacterial cell walls,
CA   elastin and other proteins.
CC   -!- Belongs to peptidase family S1E.
PR   PROSITE; PDOC00124;
DR   P27459, PRLA_ACHLY ;  P00778, PRLA_LYSEN ;  P85142, PRLA_LYSSX ;
//
ID   3.4.21.13
DE   Transferred entry: 3.4.16.5 and 3.4.16.6.
//
ID   3.4.21.14
DE   Transferred entry: 3.4.21.62, 3.4.21.63, 3.4.21.64, 3.4.21.65 and
DE   3.4.21.67.
//
ID   3.4.21.15
DE   Transferred entry: 3.4.21.63.
//
ID   3.4.21.16
DE   Deleted entry.
//
ID   3.4.21.17
DE   Deleted entry.
//
ID   3.4.21.18
DE   Deleted entry.
//
ID   3.4.21.19
DE   Glutamyl endopeptidase.
AN   Endoproteinase Glu-C.
AN   Protease V8.
AN   Staphylococcal serine proteinase.
AN   V8 proteinase.
CA   Preferential cleavage: Glu-|-Xaa, Asp-|-Xaa.
CC   -!- In appropriate buffer the specificity is restricted to Glu-|-Xaa.
CC   -!- Bonds involving bulky side-chains of hydrophobic amino acids are
CC       cleaved at a lower rate.
CC   -!- Belongs to peptidase family S1B.
PR   PROSITE; PDOC00571;
DR   P0C0Q1, GSEA_STAEP ;  Q5HN75, GSEA_STAEQ ;  P0C0Q2, GSEA_STAES ;
DR   P80057, GSEP_BACLD ;  Q2FZL2, SSPA_STAA8 ;  Q5HH35, SSPA_STAAC ;
DR   Q99V45, SSPA_STAAM ;  Q7A6A6, SSPA_STAAN ;  Q6GI34, SSPA_STAAR ;
DR   Q6GAG4, SSPA_STAAS ;  P0C1U8, SSPA_STAAU ;  Q8NX98, SSPA_STAAW ;
//
ID   3.4.21.20
DE   Cathepsin G.
CA   Specificity similar to chymotrypsin C.
CC   -!- From azurophil granules of polymorphonuclear leukocytes.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   P08311, CATG_HUMAN ;  P28293, CATG_MOUSE ;  P17977, CATG_RAT   ;
//
ID   3.4.21.21
DE   Coagulation factor VIIa.
CA   Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa.
CC   -!- Formed from the precursor factor VII.
CC   -!- The cattle enzyme is more readily inhibited by diisopropyl
CC       fluorophosphate than the human.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   P22457, FA7_BOVIN  ;  P08709, FA7_HUMAN  ;  P70375, FA7_MOUSE  ;
DR   Q2F9P4, FA7_PANPA  ;  Q2F9P2, FA7_PANTR  ;  P98139, FA7_RABIT  ;
DR   Q8K3U6, FA7_RAT    ;
//
ID   3.4.21.22
DE   Coagulation factor IXa.
AN   Christmas factor.
CA   Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa.
CC   -!- The proenzyme factor IX is activated by EC 3.4.21.27.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   P00741, FA9_BOVIN  ;  P19540, FA9_CANFA  ;  P16295, FA9_CAVPO  ;
DR   Q804X6, FA9_CHICK  ;  Q6SA95, FA9_FELCA  ;  P00740, FA9_HUMAN  ;
DR   P16294, FA9_MOUSE  ;  Q95ND7, FA9_PANTR  ;  P16293, FA9_PIG    ;
DR   P16292, FA9_RABIT  ;  P16296, FA9_RAT    ;  P16291, FA9_SHEEP  ;
//
ID   3.4.21.23
DE   Deleted entry.
//
ID   3.4.21.24
DE   Deleted entry.
//
ID   3.4.21.25
DE   Cucumisin.
CA   Hydrolysis of proteins with broad specificity.
CC   -!- From the sarcocarp of the musk melon (Cucumis melo).
CC   -!- Other endopeptidases from plants, which are less well characterized
CC       but presumably of serine-type, include euphorbain from Euphorbia
CC       cerifera, solanain from horse-nettle Solanum elaeagnifolium, hurain
CC       from Hura crepitans and tabernamontanain from Tabernamontana
CC       grandiflora.
CC   -!- Belongs to peptidase family S8.
PR   PROSITE; PDOC00125;
DR   Q39547, CUCM1_CUCME;
//
ID   3.4.21.26
DE   Prolyl oligopeptidase.
AN   Post-proline cleaving enzyme.
AN   Post-proline endopeptidase.
AN   Prolyl endopeptidase.
CA   Hydrolysis of Pro-|-Xaa >> Ala-|-Xaa in oligopeptides.
CC   -!- Found in vertebrates, plants and Flavobacterium.
CC   -!- Generally cytosolic, commonly activated by thiol compounds.
CC   -!- Belongs to peptidase family S9A.
CC   -!- Formerly EC 3.4.22.18.
PR   PROSITE; PDOC00587;
DR   Q06903, PPCE_AERHY ;  Q9XTA2, PPCE_BOVIN ;  Q86AS5, PPCE_DICDI ;
DR   P27028, PPCE_FLAME ;  P48147, PPCE_HUMAN ;  Q9QUR6, PPCE_MOUSE ;
DR   P23687, PPCE_PIG   ;  O70196, PPCE_RAT   ;  P27195, PPCF_ELIMR ;
//
ID   3.4.21.27
DE   Coagulation factor XIa.
AN   Plasma thromboplastin antecedent.
CA   Selective cleavage of Arg-|-Ala and Arg-|-Val bonds in factor IX to form
CA   factor IXa.
CC   -!- The proenzyme XI is activated by EC 3.4.21.38.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
PR   PROSITE; PDOC00376;
DR   Q5NTB3, FA11_BOVIN ;  P03951, FA11_HUMAN ;  Q91Y47, FA11_MOUSE ;
//
ID   3.4.21.28
DE   Transferred entry: 3.4.21.74.
//
ID   3.4.21.29
DE   Transferred entry: 3.4.21.74.
//
ID   3.4.21.30
DE   Transferred entry: 3.4.21.74.
//
ID   3.4.21.31
DE   Transferred entry: 3.4.21.68 and 3.4.21.73.
//
ID   3.4.21.32
DE   Brachyurin.
AN   Collagenolytic protease.
CA   Hydrolysis of proteins, with broad specificity for peptide bonds. Native
CA   collagen is cleaved about 75% of the length of the molecule from the
CA   N-terminus. Low activity on small molecule substrates of both trypsin and
CA   chymotrypsin.
CC   -!- From hepatopancreas of the fiddler crab (Uca pugilator).
CC   -!- Other serine endopeptidases that degrade collagen, but are not listed
CC       separately here, include a second endopeptidase from U.pugilator,
CC       digestive enzymes from other decapod crustacea, and an enzyme from
CC       the fungus Entomophthora coronata.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   P34153, COG1_CHIOP ;  P20731, COG1_PARCM ;  P81609, COG2_CARMA ;
DR   P34154, COG2_CHIOP ;  P34155, COG3_CHIOP ;  P20732, COGA_PARCM ;
DR   P20733, COGB_PARCM ;  P20734, COGC_PARCM ;  P00771, COGS_UCAPU ;
//
ID   3.4.21.33
DE   Deleted entry.
//
ID   3.4.21.34
DE   Plasma kallikrein.
AN   Kininogenin.
AN   Serum kallikrein.
CA   Cleaves selectively Arg-|-Xaa and Lys-|-Xaa bonds, including Lys-|-Arg
CA   and Arg-|-Ser bonds in (human) kininogen to release bradykinin.
CC   -!- Formed from plasma prokallikrein (Fletcher factor) by factor XIIa.
CC   -!- Activates coagulation factors XII, VII and plasminogen.
CC   -!- Selective for Arg > Lys in P1, in small molecule substrates.
CC   -!- Belongs to peptidase family S1.
CC   -!- Formerly EC 3.4.4.21 and EC 3.4.21.8.
PR   PROSITE; PDOC00124;
PR   PROSITE; PDOC00376;
DR   Q2KJ63, KLKB1_BOVIN;  P03952, KLKB1_HUMAN;  P26262, KLKB1_MOUSE;
DR   P14272, KLKB1_RAT  ;
//
ID   3.4.21.35
DE   Tissue kallikrein.
AN   Glandular kallikrein.
AN   Kininogenin.
CA   Preferential cleavage of Arg-|-Xaa bonds in small molecule substrates.
CA   Highly selective action to release kallidin (lysyl-bradykinin) from
CA   kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa.
CC   -!- Formed from tissue prokallikrein by activation with trypsin.
CC   -!- A large number of tissue kallikrein-related sequences have been
CC       reported for rats and mice, though fewer seem to exist in other
CC       mammals.
CC   -!- The few that have been isolated and tested on substrates include
CC       mouse EC 3.4.21.54, submandibular proteinase a, epidermal growth-
CC       factor-binding protein, nerve growth factor gamma-subunit, rat tonin,
CC       submaxillary proteinases A and B, T-kininogenase, kallikreins K7 and
CC       K8.
CC   -!- The rat enzyme is unusual in liberating bradykinin directly from
CC       autologous kininogens by cleavage at two Arg-|-Xaa bonds.
CC   -!- Belongs to peptidase family S1.
CC   -!- Formerly EC 3.4.21.8.
PR   PROSITE; PDOC00124;
DR   P09582, ESTA_CANFA ;  P15946, K1B11_MOUSE;  Q61759, K1B21_MOUSE;
DR   P15948, K1B22_MOUSE;  Q61754, K1B24_MOUSE;  P36369, K1B26_MOUSE;
DR   P00755, K1KB1_MOUSE;  P00756, K1KB3_MOUSE;  P15945, K1KB5_MOUSE;
DR   P07628, K1KB8_MOUSE;  P15949, K1KB9_MOUSE;  P36375, KLK10_RAT  ;
DR   P36376, KLK12_RAT  ;  P12322, KLK1_CAVPO ;  P06870, KLK1_HUMAN ;
DR   Q07276, KLK1_MACFA ;  P15947, KLK1_MOUSE ;  Q28773, KLK1_PAPHA ;
DR   P00758, KLK1_RAT   ;  P12323, KLK2_CAVPO ;  Q6H321, KLK2_HORSE ;
DR   P20151, KLK2_HUMAN ;  P00759, KLK2_RAT   ;  P15950, KLK3_RAT   ;
DR   P36374, KLK6_RAT   ;  P36373, KLK7_RAT   ;  P07647, KLK9_RAT   ;
DR   P32824, KLKR_PRANA ;  P00752, KLK_PIG    ;
//
ID   3.4.21.36
DE   Pancreatic elastase.
AN   Pancreatic elastase I.
AN   Pancreatopeptidase E.
CA   Hydrolysis of proteins, including elastin. Preferential cleavage:
CA   Ala-|-Xaa.
CC   -!- Formed by activation of proelastase from mammalian pancreas by
CC       trypsin.
CC   -!- Belongs to peptidase family S1.
CC   -!- Formerly EC 3.4.4.7 and EC 3.4.21.11.
PR   PROSITE; PDOC00124;
DR   Q28153, CELA1_BOVIN;  Q867B0, CELA1_CANFA;  Q5R1M5, CELA1_FELCA;
DR   Q9UNI1, CELA1_HUMAN;  O46644, CELA1_MACFA;  P00772, CELA1_PIG  ;
DR   P00773, CELA1_RAT  ;  Q7SIG3, ELA1_SALSA ;
//
ID   3.4.21.37
DE   Leukocyte elastase.
AN   Bone marrow serine protease.
AN   Lysosomal elastase.
AN   Medullasin.
AN   Neutrophil elastase.
CA   Hydrolysis of proteins, including elastin. Preferential cleavage:
CA   Val-|-Xaa > Ala-|-Xaa.
CC   -!- Differs from pancreatic elastase in specificity on synthetic
CC       substrates and in inhibitor sensitivity.
CC   -!- Belongs to peptidase family S1.
CC   -!- Formerly EC 3.4.4.7 and EC 3.4.21.11.
PR   PROSITE; PDOC00124;
DR   P08246, ELNE_HUMAN ;  Q3UP87, ELNE_MOUSE ;
//
ID   3.4.21.38
DE   Coagulation factor XIIa.
AN   Hageman factor.
CA   Selective cleavage of Arg-|-Ile bonds in factor VII to form factor VIIa
CA   and factor XI to form factor XIa.
CC   -!- Also activates plasma prekallikrein and plasminogen.
CC   -!- Formed from the proenzyme, factor XII, by plasma kallikrein or factor
CC       XIIa.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   P98140, FA12_BOVIN ;  Q04962, FA12_CAVPO ;  P00748, FA12_HUMAN ;
DR   Q80YC5, FA12_MOUSE ;  O97507, FA12_PIG   ;  D3ZTE0, FA12_RAT   ;
//
ID   3.4.21.39
DE   Chymase.
AN   Mast cell protease I.
AN   Skeletal muscle (SK) protease.
CA   Preferential cleavage: Phe-|-Xaa > Tyr-|-Xaa > Trp-|-Xaa > Leu-|-Xaa.
CC   -!- In mast cell granules.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   P21842, CMA1_CANFA ;  A7WPL7, CMA1_CAVPO ;  P23946, CMA1_HUMAN ;
DR   P56435, CMA1_MACFA ;  P21844, CMA1_MOUSE ;  P52195, CMA1_PAPHA ;
DR   P85202, CMA1_RABIT ;  P50339, CMA1_RAT   ;  P09650, MCPT1_RAT  ;
//
ID   3.4.21.40
DE   Deleted entry.
//
ID   3.4.21.41
DE   Complement subcomponent C1r.
CA   Selective cleavage of Lys(or Arg)-|-Ile bond in complement subcomponent
CA   C1s to form the active form of C1s (EC 3.4.21.42).
CC   -!- Activates C1s by proteolytic cleavage so that it can, in turn,
CC       activate C2 and C4.
CC   -!- Activated from proenzyme C1r in plasma by autocatalytic mechanism
CC       during activation of the complement system by the 'classical' route.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   Q8CG16, C1RA_MOUSE ;  Q8CFG9, C1RB_MOUSE ;  P00736, C1R_HUMAN  ;
DR   Q4R577, C1R_MACFA  ;  Q5R1W3, C1R_PANTR  ;  Q5R544, C1R_PONAB  ;
//
ID   3.4.21.42
DE   Complement subcomponent C1s.
AN   C1s esterase.
CA   Cleavage of Arg-|-Ala bond in complement component C4 to form C4a and
CA   C4b, and Lys(or Arg)-|-Lys bond in complement component C2 to form C2a
CA   and C2b: the 'classical' pathway C3 convertase.
CC   -!- Activated from proenzyme C1s in plasma by the activated complement
CC       subcomponent C1r.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   Q0VCX1, C1S_BOVIN  ;  P09871, C1S_HUMAN  ;  Q69DK8, C1S_PIG    ;
DR   Q6P6T1, C1S_RAT    ;  Q8CG14, CS1A_MOUSE ;  Q8CFG8, CS1B_MOUSE ;
//
ID   3.4.21.43
DE   Classical-complement-pathway C3/C5 convertase.
AN   C3 convertase.
AN   C5 convertase.
AN   Complement C2.
CA   Selective cleavage of Arg-|-Ser bond in complement component C3 alpha-
CA   chain to form C3a and C3b, and Arg-|-Xaa bond in complement component C5
CA   alpha-chain to form C5a and C5b.
CC   -!- A complex of complement fragments C4b, C2a and C2b.
CC   -!- Belongs to peptidase family S1.
CC   -!- Formerly EC 3.4.21.44.
PR   PROSITE; PDOC00124;
DR   Q3SYW2, CO2_BOVIN  ;  Q863A0, CO2_GORGO  ;  P06681, CO2_HUMAN  ;
DR   P21180, CO2_MOUSE  ;  Q8SQ74, CO2_PANTR  ;  Q8SQ75, CO2_PONPY  ;
//
ID   3.4.21.44
DE   Transferred entry: 3.4.21.43.
//
ID   3.4.21.45
DE   Complement factor I.
AN   C3b inactivator.
AN   C3b/C4b inactivator.
AN   Complement component C3b inactivator.
CA   Inactivates complement subcomponents C3b, iC3b and C4b by proteolytic
CA   cleavage.
CC   -!- Cleavage of complement subcomponent C3b requires its binding to
CC       cofactor H or complement receptor CR1; cleavage of iC3b requires
CC       complement receptor CR1; cleavage of C4b requires C4b-binding
CC       protein.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   P05156, CFAI_HUMAN ;  Q61129, CFAI_MOUSE ;  Q5R5A4, CFAI_PONAB ;
DR   Q9WUW3, CFAI_RAT   ;
//
ID   3.4.21.46
DE   Complement factor D.
AN   C3 convertase activator.
AN   C3 proactivator convertase.
CA   Selective cleavage of Arg-|-Lys bond in complement factor B when in
CA   complex with complement subcomponent C3b or with cobra venom factor.
CC   -!- A component of the alternative pathway of complement activation.
CC   -!- This reaction is analogous to the activation of complement component
CC       C2 by activated complement subcomponent C1s.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   Q3T0A3, CFAD_BOVIN ;  P00746, CFAD_HUMAN ;  P03953, CFAD_MOUSE ;
DR   P51779, CFAD_PIG   ;  P32038, CFAD_RAT   ;
//
ID   3.4.21.47
DE   Alternative-complement-pathway C3/C5 convertase.
AN   C3 convertase.
AN   C3 proactivator.
AN   C5 convertase.
AN   Complement component C3/C5 convertase (alternative).
AN   Complement factor B.
AN   Properdin factor B.
CA   Cleavage of Arg-|-Ser bond in complement component C3 alpha-chain to
CA   yield C3a and C3b, and Arg-|-Xaa bond in complement component C5 alpha-
CA   chain to yield C5a and C5b.
CC   -!- A bimolecular complex of complement fragment Bb with either C3b or
CC       cobra venom factor; Bb contains the active site.
CC   -!- Bb is formed by cleavage of proenzyme factor B by factor D.
CC   -!- Cleavage of complement component C5 requires additional C3b which
CC       binds C5 and renders it susceptible to cleavage by C3b,Bb complex.
CC   -!- C3b,Bb is stabilized in plasma by factor P.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   P81187, CFAB_BOVIN ;  Q864V9, CFAB_GORGO ;  P00751, CFAB_HUMAN ;
DR   P04186, CFAB_MOUSE ;  Q864W0, CFAB_PANTR ;  Q03710, CFAB_PIG   ;
DR   Q864W1, CFAB_PONPY ;
//
ID   3.4.21.48
DE   Cerevisin.
AN   Proteinase yscB.
AN   Yeast proteinase B.
CA   Hydrolysis of proteins with broad specificity, and of Bz-Arg-OEt >
CA   Ac-Tyr-OEt. Does not hydrolyze peptide amides.
CC   -!- Contains a Cys residue near the active site His, and is inhibited by
CC       mercurials.
CC   -!- Proteinase ycaB is a similar enzyme from the yeast Candida albicans.
CC   -!- Belongs to peptidase family S8.
CC   -!- Formerly EC 3.4.22.9.
PR   PROSITE; PDOC00125;
DR   P09232, PRTB_YEAST ;
//
ID   3.4.21.49
DE   Hypodermin C.
AN   Hypoderma collagenase.
CA   Hydrolysis of proteins including native collagen at Xaa-|-Ala bond
CA   leaving an N-terminal (75%) and a C-terminal (25%) fragment.
CC   -!- Little action on small molecule substrates of trypsin, chymotrypsin,
CC       elastase or microbial collagenases.
CC   -!- Belongs to peptidase family S1.
DR   P08897, COGS_HYPLI ;
//
ID   3.4.21.50
DE   Lysyl endopeptidase.
AN   Achromobacter proteinase I.
AN   Lysyl bond specific proteinase.
CA   Preferential cleavage: Lys-|-Xaa, including Lys-|-Pro.
CC   -!- Isolated from Achromobacter lyticus.
CC   -!- Enzymes with similar specificity are produced by Lysobacter
CC       enzymogenes (endoproteinase Lys-C) and Pseudomonas aeruginosa (Ps-1).
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   P15636, API_ACHLY  ;  Q7M135, LYSC_LYSEN ;  Q9HWK6, LYSC_PSEAE ;
//
ID   3.4.21.51
DE   Deleted entry.
//
ID   3.4.21.52
DE   Deleted entry.
//
ID   3.4.21.53
DE   Endopeptidase La.
AN   ATP-dependent protease La.
AN   ATP-dependent serine proteinase.
CA   Hydrolysis of proteins in presence of ATP.
CC   -!- ATP hydrolysis is linked with peptide bond hydrolysis.
CC   -!- Vanadate inhibits both reactions.
CC   -!- A similar enzyme occurs in animal mitochondria.
CC   -!- Belongs to peptidase family S16.
PR   PROSITE; PDOC00803;
DR   P37945, LON1_BACSU ;  Q6ML73, LON1_BDEBA ;  Q59185, LON1_BORBU ;
DR   Q6AS16, LON1_DESPS ;  A9B5N1, LON1_HERA2 ;  P36773, LON1_MYXXA ;
DR   Q3A701, LON1_PELCD ;  A9ETZ9, LON1_SORC5 ;  A0LEE9, LON1_SYNFM ;
DR   Q72KS4, LON1_THET2 ;  Q31GE9, LON1_THICR ;  P42425, LON2_BACSU ;
DR   Q6MGP8, LON2_BDEBA ;  O51558, LON2_BORBU ;  Q6AK61, LON2_DESPS ;
DR   A9B3R2, LON2_HERA2 ;  P36774, LON2_MYXXA ;  Q3A334, LON2_PELCD ;
DR   A9GBF1, LON2_SORC5 ;  A0LG61, LON2_SYNFM ;  Q72JM6, LON2_THET2 ;
DR   Q31FD3, LON2_THICR ;  A9GIS9, LON3_SORC5 ;  A9F8L0, LON4_SORC5 ;
DR   B7GXS7, LON_ACIB3  ;  Q1IPZ8, LON_ACIBL  ;  B3ERM8, LON_AMOA5  ;
DR   Q2IIK1, LON_ANADE  ;  O66605, LON_AQUAE  ;  Q2NJE3, LON_AYWBP  ;
DR   P77810, LON_AZOBR  ;  A8HYF7, LON_AZOC5  ;  A0RJ87, LON_BACAH  ;
DR   B5RL78, LON_BORDL  ;  P36772, LON_BRECH  ;  Q2YPX3, LON_BRUA2  ;
DR   P0C113, LON_BRUAB  ;  Q8YHC6, LON_BRUME  ;  Q8G0I7, LON_BRUSU  ;
DR   P57549, LON_BUCAI  ;  Q8K988, LON_BUCAP  ;  Q89A99, LON_BUCBP  ;
DR   B2TFQ5, LON_BURPP  ;  A4XJL4, LON_CALS8  ;  A7ZEJ3, LON_CAMC1  ;
DR   O69300, LON_CAMJE  ;  B8GX12, LON_CAUCN  ;  P0CAW0, LON_CAUCR  ;
DR   A9WGB5, LON_CHLAA  ;  B8G736, LON_CHLAD  ;  Q9PK50, LON_CHLMU  ;
DR   Q9Z9F4, LON_CHLPN  ;  B3QSJ7, LON_CHLT3  ;  O84348, LON_CHLTR  ;
DR   Q97FT9, LON_CLOAB  ;  A6LSV5, LON_CLOB8  ;  Q180E4, LON_CLOD6  ;
DR   A9KH99, LON_CLOPH  ;  B5Y8Q8, LON_COPPD  ;  Q11QT1, LON_CYTH3  ;
DR   Q9RXG4, LON_DEIRA  ;  B8F9K1, LON_DESAA  ;  B8J198, LON_DESDA  ;
DR   A8ZX50, LON_DESOH  ;  A4J7L6, LON_DESRM  ;  Q72CE6, LON_DESVH  ;
DR   A5EWF3, LON_DICNV  ;  B5YFG2, LON_DICT6  ;  P0A9M1, LON_ECOL6  ;
DR   P0A9M0, LON_ECOLI  ;  B2KCC0, LON_ELUMP  ;  P46067, LON_ERWAM  ;
DR   A7HK39, LON_FERNB  ;  B0S2N4, LON_FINM2  ;  A5FG89, LON_FLAJ1  ;
DR   Q0RPW3, LON_FRAAA  ;  B0TZA7, LON_FRAP2  ;  Q8RHK0, LON_FUSNN  ;
DR   B5EDX8, LON_GEOBB  ;  B3E7K2, LON_GEOLS  ;  Q39QP7, LON_GEOMG  ;
DR   P43864, LON_HAEIN  ;  B8CY71, LON_HALOH  ;  B0TFI9, LON_HELMI  ;
DR   Q9ZJL3, LON_HELPJ  ;  P55995, LON_HELPY  ;  Q1MS21, LON_LAWIP  ;
DR   Q72UP9, LON_LEPIC  ;  A0L516, LON_MAGSM  ;  Q469F5, LON_METBF  ;
DR   B8EMF2, LON_METSB  ;  Q2NEP8, LON_METST  ;  B3PN08, LON_MYCA5  ;
DR   A5IYF2, LON_MYCAP  ;  P47481, LON_MYCGE  ;  Q600B5, LON_MYCH2  ;
DR   Q6KI22, LON_MYCMO  ;  Q6MTF4, LON_MYCMS  ;  Q8EV77, LON_MYCPE  ;
DR   P78025, LON_MYCPN  ;  Q4A696, LON_MYCS5  ;  O31147, LON_MYCSM  ;
DR   Q2GE60, LON_NEOSM  ;  Q3JBB6, LON_NITOC  ;  B3CUN9, LON_ORITI  ;
DR   A6LD45, LON_PARD8  ;  Q6ME13, LON_PARUW  ;  B4RI01, LON_PHEZH  ;
DR   B2RII6, LON_PORG3  ;  O69177, LON_RHIME  ;  Q1RID6, LON_RICBR  ;
DR   Q92HZ1, LON_RICCN  ;  Q4ULN0, LON_RICFE  ;  Q9ZD92, LON_RICPR  ;
DR   Q68WS8, LON_RICTY  ;  A7NM80, LON_ROSCS  ;  A8M1E8, LON_SALAI  ;
DR   Q32JJ5, LON_SHIDS  ;  Q026Q2, LON_SOLUE  ;  A8Z5Z0, LON_SULMW  ;
DR   B2V6N0, LON_SULSY  ;  Q2LVS9, LON_SYNAS  ;  Q0AWF3, LON_SYNWW  ;
DR   A8F811, LON_THELT  ;  O83536, LON_TREPA  ;  B1GZQ6, LON_UNCTG  ;
DR   B1AIY7, LON_UREP2  ;  P74956, LON_VIBPA  ;  B3CLB3, LON_WOLPP  ;
DR   Q5H432, LON_XANOR  ;
//
ID   3.4.21.54
DE   Gamma-renin.
CA   Cleavage of the Leu-|-Leu bond in synthetic tetradecapeptide renin
CA   substrate, to produce angiotensin I, but not active on natural
CA   angiotensinogen. Also hydrolyzes Bz-Arg-p-nitroanilide.
CC   -!- Unlike EC 3.4.23.15, does not act on natural angiotensinogen.
CC   -!- A member of the tissue kallikrein family, from submandibular glands
CC       of male mice.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   P04071, K1B16_MOUSE;
//
ID   3.4.21.55
DE   Venombin AB.
AN   Bitis gabonica serine proteinase.
AN   Gabonase.
CA   Preferential cleavage: Arg-|-Xaa bonds in fibrinogen to form fibrin and
CA   release fibrinopeptides A and B.
CC   -!- From the venom of the Gaboon viper Bitis gabonica.
CC   -!- Activates factor XIII.
CC   -!- Not inhibited by antithrombin III/heparin or hirudin, unlike
CC       EC 3.4.21.5.
DR   P0C577, VSPG_BITGA ;
//
ID   3.4.21.56
DE   Deleted entry.
//
ID   3.4.21.57
DE   Leucyl endopeptidase.
AN   Leucine-specific serine proteinase.
AN   Plant Leu-proteinase.
CA   Hydrolysis of proteins. Preferential cleavage: Leu-|-Xaa in small
CA   molecule substrates.
CC   -!- The enzyme from spinach leaves shows high specificity for leucine in
CC       peptides and 4-nitroanilides.
//
ID   3.4.21.58
DE   Deleted entry.
//
ID   3.4.21.59
DE   Tryptase.
AN   Lung tryptase.
AN   Mast cell protease II.
AN   Mast cell tryptase.
AN   Pituitary tryptase.
AN   Skin tryptase.
CA   Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa, but with more restricted
CA   specificity than trypsin.
CC   -!- Occurs as a tetrameric molecule with high affinity for heparin,
CC       in mast cell granules.
CC   -!- Not inhibited by alpha-1-proteinase inhibitor of alpha-2-
CC       macroglobulin.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   Q15661, TRYB1_HUMAN;  Q02844, TRYB1_MOUSE;  P27435, TRYB1_RAT  ;
DR   P20231, TRYB2_HUMAN;  P21845, TRYB2_MOUSE;  P50343, TRYB2_RAT  ;
DR   Q9BZJ3, TRYD_HUMAN ;  P15944, TRYT_CANFA ;  P50342, TRYT_MERUN ;
DR   Q9N2D1, TRYT_PIG   ;  Q9XSM2, TRYT_SHEEP ;
//
ID   3.4.21.60
DE   Scutelarin.
AN   Taipan activator.
CA   Selective cleavage of Arg-|-Thr and Arg-|-Ile in prothrombin to form
CA   thrombin and two inactive fragments.
CC   -!- From the venom of the Taipan snake (Oxyuranus scutellatus).
CC   -!- Converts prothrombin to thrombin.
CC   -!- Specificity is similar to that of Factor Xa (EC 3.4.21.6).
CC   -!- However, unlike Factor Xa this enzyme can cleave its target in the
CC       absence of coagulation Factor Va.
CC   -!- Activity is potentiated by phospholipid and Ca(2+) which binds via
CC       gamma-carboxyglutamic acid residues.
CC   -!- Similar enzymes are known from the venom of other Australian elapid
CC       snakes, including Pseudonaja textilis textilis, Oxyuranus
CC       microlepidotus and Demansia nuchalis affinis.
CC   -!- Formerly EC 3.4.99.28.
//
ID   3.4.21.61
DE   Kexin.
AN   Paired-basic endopeptidase.
AN   Prohormone-processing endoprotease.
AN   Proteinase yscF.
AN   Yeast KEX2 protease.
CA   Cleavage of -Lys-Arg-|-Xaa- and -Arg-Arg-|-Xaa- bonds to process yeast
CA   alpha-factor pheromone and killer toxin precursors.
CC   -!- Calcium activated.
CC   -!- Inhibited by p-mercuribenzoate.
CC   -!- Belongs to peptidase family S8.
CC   -!- Formerly EC 3.4.22.23.
PR   PROSITE; PDOC00125;
DR   O13359, KEX2_CANAL ;  P13134, KEX2_YEAST ;
//
ID   3.4.21.62
DE   Subtilisin.
CA   Hydrolysis of proteins with broad specificity for peptide bonds, and a
CA   preference for a large uncharged residue in P1. Hydrolyzes peptide
CA   amides.
CC   -!- Subtilisin is a serine endopeptidase that evolved independently of
CC       chymotrypsin.
CC   -!- It contains no cysteine residues (although these are found in
CC       homologous enzymes).
CC   -!- Species variants include subtilisin BPN' (also subtilisin B,
CC       subtilopeptidase C, nagarse, nagarse proteinase, subtilisin Novo,
CC       bacterial proteinase Novo) and subtilisin Carlsberg (subtilisin A,
CC       subtilopeptidase A, alcalase Novo).
CC   -!- Similar enzymes are produced by various Bacillus subtilis strains and
CC       other Bacillus species.
CC   -!- Belongs to peptidase family S8.
CC   -!- Formerly EC 3.4.4.16 and EC 3.4.21.14.
PR   PROSITE; PDOC00125;
DR   P29599, SUBB_BACLE ;  P00781, SUBD_BACLI ;  P35835, SUBN_BACNA ;
DR   P29600, SUBS_BACLE ;  P00782, SUBT_BACAM ;  P00780, SUBT_BACLI ;
DR   P07518, SUBT_BACPU ;  P28842, SUBT_BACS9 ;  P00783, SUBT_BACSA ;
DR   P04189, SUBT_BACSU ;  P29142, SUBT_GEOSE ;
//
ID   3.4.21.63
DE   Oryzin.
AN   Aspergillopeptidase B.
AN   Aspergillus alkaline proteinase.
CA   Hydrolysis of proteins with broad specificity, and of Bz-Arg-OEt >
CA   Ac-Tyr-OEt. Does not hydrolyze peptide amides.
CC   -!- Predominant extracellular alkaline endopeptidase of the mold
CC       Aspergillus oryzae.
CC   -!- Identical or closely related enzymes are produced by A.flavus and
CC       A.sojae.
CC   -!- Belongs to peptidase family S8.
CC   -!- Formerly EC 3.4.4.16, EC 3.4.21.14 and EC 3.4.21.15.
PR   PROSITE; PDOC00125;
DR   B0Y473, ALP2_ASPFC ;  P87184, ALP2_ASPFU ;  A1CIA7, ORYZ_ASPCL ;
DR   B0Y708, ORYZ_ASPFC ;  P35211, ORYZ_ASPFL ;  B8N106, ORYZ_ASPFN ;
DR   P28296, ORYZ_ASPFU ;  P12547, ORYZ_ASPOR ;  Q00208, ORYZ_EMENI ;
DR   A1CWF3, ORYZ_NEOFI ;
//
ID   3.4.21.64
DE   Peptidase K.
AN   Endopeptidase K.
AN   Proteinase K.
AN   Tritirachium album proteinase K.
AN   Tritirachium alkaline proteinase.
CA   Hydrolysis of keratin, and of other proteins with subtilisin-like
CA   specificity. Hydrolyzes peptide amides.
CC   -!- From the mold Tritirachium album Limber.
CC   -!- Contains two disulfide bridges and one free Cys near the active site
CC       His.
CC   -!- Belongs to peptidase family S8.
CC   -!- Formerly EC 3.4.4.16 and EC 3.4.21.14.
PR   PROSITE; PDOC00125;
DR   P06873, PRTK_TRIAL ;
//
ID   3.4.21.65
DE   Thermomycolin.
AN   Thermomycolase.
CA   Rather non-specific hydrolysis of proteins. Preferential cleavage:
CA   -Ala-|-Xaa-, -Tyr-|-Xaa-, -Phe-|-Xaa- in small molecular substrates.
CC   -!- From the thermophilic fungus Malbranchea pulchella var. sulfurea.
CC   -!- Contains Cys, but not inhibited by p-mercuribenzoate.
CC   -!- Very thermostable.
CC   -!- Belongs to peptidase family S8.
CC   -!- Formerly EC 3.4.4.16 and EC 3.4.21.14.
PR   PROSITE; PDOC00125;
DR   P13858, THEM_MALSU ;
//
ID   3.4.21.66
DE   Thermitase.
AN   Thermophilic Streptomyces serine protease.
CA   Hydrolysis of proteins, including collagen.
CC   -!- From Thermoactinomyces vulgaris containing a single Cys, near the
CC       active site His, and inhibited by p-mercuribenzoate.
CC   -!- The N-terminal extension of the polypeptide chain relative to
CC       subtilisin contributes to calcium-binding and the high
CC       thermostability.
CC   -!- The amino acid composition and properties of the thermostable enzyme
CC       from Streptomyces rectus var. proteolyticus are closely similar.
CC   -!- Belongs to peptidase family S8.
CC   -!- Formerly EC 3.4.4.16.
PR   PROSITE; PDOC00125;
DR   P04072, THET_THEVU ;
//
ID   3.4.21.67
DE   Endopeptidase So.
AN   E.coli cytoplasmic proteinase.
CA   Hydrolysis of proteins, but not Bz-Tyr-OEt, Ac-Phe-beta-naphthylester,
CA   or Bz-Arg-OEt.
CC   -!- Cytoplasmic peptidase.
CC   -!- Inhibited by Tos-Phe-CH(2)Cl, but not by Tos-Lys-CH(2)Cl.
CC   -!- Formerly EC 3.4.4.16 and EC 3.4.21.14.
//
ID   3.4.21.68
DE   T-plasminogen activator.
AN   Tissue plasminogen activator.
AN   Tissue-type plasminogen activator.
AN   tPA.
CA   Specific cleavage of Arg-|-Val bond in plasminogen to form plasmin.
CC   -!- From a wide variety of mammalian tissues, especially endothelial
CC       cells.
CC   -!- Secreted as a single chain precursor which is cleaved to a two-chain
CC       form by plasmin.
CC   -!- Activity is considerably enhanced by fibrin.
CC   -!- Belongs to peptidase family S1.
CC   -!- Formerly EC 3.4.21.31 and EC 3.4.99.26.
PR   PROSITE; PDOC00124;
DR   Q28198, TPA_BOVIN  ;  P00750, TPA_HUMAN  ;  P11214, TPA_MOUSE  ;
DR   Q8SQ23, TPA_PIG    ;  Q5R8J0, TPA_PONAB  ;  P19637, TPA_RAT    ;
DR   P98119, URT1_DESRO ;  P15638, URT2_DESRO ;  P98121, URTB_DESRO ;
DR   P49150, URTG_DESRO ;
//
ID   3.4.21.69
DE   Protein C (activated).
AN   Activated blood coagulation factor XIV.
AN   Autoprothrombin IIA.
CA   Degradation of blood coagulation factors Va and VIIIa.
CC   -!- One of the gamma-carboxyglutamic acid-containing coagulation factors.
CC   -!- Formed from protein C, the proenzyme that circulates in plasma,
CC       by the action of a complex of thrombin with thrombomodulin, or by
CC       serine endopeptidases present in several snake venoms.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   P00745, PROC_BOVIN ;  Q28278, PROC_CANFA ;  Q28315, PROC_CAPHI ;
DR   Q28412, PROC_FELCA ;  Q28380, PROC_HORSE ;  P04070, PROC_HUMAN ;
DR   Q28506, PROC_MACMU ;  P33587, PROC_MOUSE ;  Q9GLP2, PROC_PIG   ;
DR   Q28661, PROC_RABIT ;  P31394, PROC_RAT   ;
//
ID   3.4.21.70
DE   Pancreatic endopeptidase E.
AN   Cholesterol-binding proteinase.
AN   Elastase III.
CA   Preferential cleavage: Ala-|-Xaa. Does not hydrolyze elastin.
CC   -!- From pancreatic juice.
CC   -!- Unlike elastases, has an acidic pI.
CC   -!- Binds cholesterol.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   P09093, CEL3A_HUMAN;  P08861, CEL3B_HUMAN;  O19023, CEL3B_MACMU;
//
ID   3.4.21.71
DE   Pancreatic elastase II.
CA   Preferential cleavage: Leu-|-Xaa, Met-|-Xaa and Phe-|-Xaa. Hydrolyzes
CA   elastin.
CC   -!- Formed by activation of proelastase II from mammalian pancreas by
CC       trypsin.
CC   -!- Usually, only one of the pancreatic elastases (see also EC 3.4.21.36)
CC       is expressed in a given species; human pancreatic elastase is of type
CC       II.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   Q29461, CEL2A_BOVIN;  P08217, CEL2A_HUMAN;  P05208, CEL2A_MOUSE;
DR   P08419, CEL2A_PIG  ;  P00774, CEL2A_RAT  ;  P08218, CEL2B_HUMAN;
//
ID   3.4.21.72
DE   IgA-specific serine endopeptidase.
AN   IgA protease.
AN   Immunoglobulin A1 protease.
CA   Cleavage of immunoglobulin A molecules at certain Pro-|-Xaa bonds in the
CA   hinge region. No small molecule substrates are known.
CC   -!- Species variants differing slightly in specificity are secreted by
CC       Gram-negative bacteria Neisseria gonorrhoeae and Haemophilus
CC       influenzae.
CC   -!- Some other bacterial endopeptidases with similar specificity are of
CC       metallotype (see EC 3.4.24.13).
CC   -!- Belongs to peptidase family S6.
DR   P44969, IGA0_HAEIN ;  P42782, IGA1_HAEIF ;  P45384, IGA2_HAEIF ;
DR   P45385, IGA3_HAEIF ;  P45386, IGA4_HAEIF ;  P09790, IGA_NEIGO  ;
//
ID   3.4.21.73
DE   U-plasminogen activator.
AN   Cellular plasminogen activator.
AN   Urinary plasminogen activator.
AN   Urokinase.
CA   Specific cleavage of Arg-|-Val bond in plasminogen to form plasmin.
CC   -!- Formed from the inactive precursor by action of plasmin or plasma
CC       kallikrein.
CC   -!- Differs in structure from EC 3.4.21.68, and does not bind to fibrin.
CC   -!- Belongs to peptidase family S1.
CC   -!- Formerly EC 3.4.21.31 and EC 3.4.99.26.
PR   PROSITE; PDOC00124;
DR   Q05589, UROK_BOVIN ;  P15120, UROK_CHICK ;  P00749, UROK_HUMAN ;
DR   P06869, UROK_MOUSE ;  P16227, UROK_PAPCY ;  P04185, UROK_PIG   ;
DR   Q5RF29, UROK_PONAB ;  Q8MHY7, UROK_RABIT ;  P29598, UROK_RAT   ;
//
ID   3.4.21.74
DE   Venombin A.
CA   Selective cleavage of Arg-|-Xaa bond in fibrinogen, to form fibrin,
CA   and release fibrinopeptide A. The specificity of further degradation of
CA   fibrinogen varies with species origin of the enzyme.
CC   -!- A somewhat thrombin-like enzyme from venoms of snakes of the
CC       viper/rattlesnake group.
CC   -!- Species variants of the enzyme include ancrod from Agkistrodon
CC       rhodostoma (Malayan pit viper), batroxobin from Bothrops atrox (South
CC       American pit viper) and crotalase from Crotalus adamanteus (Eastern
CC       diamondback rattlesnake).
CC   -!- Does not require activation by calcium.
CC   -!- Belongs to peptidase family S1.
CC   -!- Formerly EC 3.4.21.28, EC 3.4.21.29 and EC 3.4.21.30.
PR   PROSITE; PDOC00124;
DR   Q7LZF4, VSP4A_CERCE;  P81661, VSPA_BOTJA ;  P26324, VSPF1_AGKRH;
DR   P47797, VSPF2_AGKRH;  P04971, VSPF_BOTAT ;  Q9PS28, VSPF_CERCE ;
DR   Q9PRP4, VSPF_LACMR ;  P33589, VSPF_LACMU ;  Q7SYF1, VSPP_CERCE ;
//
ID   3.4.21.75
DE   Furin.
AN   Dibasic processing enzyme.
AN   Paired basic amino acid residue cleaving enzyme.
AN   Prohormone convertase.
CA   Release of mature proteins from their proproteins by cleavage of -Arg-
CA   Xaa-Yaa-Arg-|-Zaa- bonds, where Xaa can be any amino acid and Yaa is Arg
CA   or Lys. Releases albumin, complement component C3 and von Willebrand
CA   factor from their respective precursors.
CC   -!- Activated by calcium.
CC   -!- Belongs to peptidase family S8.
PR   PROSITE; PDOC00125;
DR   P26016, FUR11_DROME;  P30430, FUR1C_DROME;  P30432, FUR2_DROME ;
DR   P29119, FURI1_XENLA;  Q28193, FURIN_BOVIN;  P09958, FURIN_HUMAN;
DR   P23188, FURIN_MOUSE;  P23377, FURIN_RAT  ;
//
ID   3.4.21.76
DE   Myeloblastin.
AN   Leukocyte proteinase 3.
AN   Proteinase 3.
AN   Wegener's autoantigen.
CA   Hydrolysis of proteins, including elastin, by preferential cleavage:
CA   -Ala-|-Xaa- > -Val-|-Xaa-.
CC   -!- Not inhibited by secretory leukocyte proteinase inhibitor.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   P24158, PRTN3_HUMAN;  Q61096, PRTN3_MOUSE;
//
ID   3.4.21.77
DE   Semenogelase.
AN   Gamma-seminoprotein.
AN   P-30 antigen.
AN   Prostate-specific antigen.
AN   Seminin.
CA   Preferential cleavage: -Tyr-|-Xaa-.
CC   -!- Slowly inhibited by alpha-1-antichymotrypsin.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   P07288, KLK3_HUMAN ;  Q6DT45, KLK3_MACFA ;  P33619, KLK3_MACMU ;
//
ID   3.4.21.78
DE   Granzyme A.
AN   Cytotoxic T-lymphocyte proteinase 1.
CA   Hydrolysis of proteins, including fibronectin, type IV collagen and
CA   nucleolin. Preferential cleavage: -Arg-|-Xaa-, -Lys-|-Xaa- >> -Phe-|-Xaa-
CA   in small molecule substrates.
CC   -!- From cytotoxic T lymphocyte granules.
CC   -!- The human enzyme does not cleave Phe-|-Xaa.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   Q7YRZ7, GRAA_BOVIN ;  P12544, GRAA_HUMAN ;  P11032, GRAA_MOUSE ;
//
ID   3.4.21.79
DE   Granzyme B.
AN   Cytotoxic t-lymphocyte proteinase 2.
CA   Preferential cleavage: -Asp-|-Xaa- >> -Asn-|-Xaa- > -Met-|-Xaa-,
CA   -Ser-|-Xaa-.
CC   -!- From cytotoxic T lymphocyte granules.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   P10144, GRAB_HUMAN ;  P04187, GRAB_MOUSE ;  P18291, GRAB_RAT   ;
//
ID   3.4.21.80
DE   Streptogrisin A.
AN   Pronase enzyme A.
AN   SGPA.
AN   Streptomyces protease A.
CA   Hydrolysis of proteins with specificity similar to chymotrypsin.
CC   -!- Not inhibited by Tos-Phe-CH(2)Cl or ovomucoid.
CC   -!- Belongs to peptidase family S1E.
PR   PROSITE; PDOC00124;
DR   P00776, PRTA_STRGR ;
//
ID   3.4.21.81
DE   Streptogrisin B.
AN   Pronase enzyme B.
AN   SGPB.
AN   Streptomyces protease B.
CA   Hydrolysis of proteins with trypsin-like specificity.
CC   -!- Belongs to peptidase family S1E.
PR   PROSITE; PDOC00124;
DR   P00777, PRTB_STRGR ;
//
ID   3.4.21.82
DE   Glutamyl endopeptidase II.
AN   GluSGP.
AN   Glutamic acid-specific protease.
CA   Preferential cleavage: -Glu-|-Xaa- >> -Asp-|-Xaa-. Preference for Pro or
CA   Leu at P2 and Phe at P3. Cleavage of -Glu-|-Asp- and -Glu-|-Pro- bonds is
CA   slow.
CC   -!- Inhibited by (18-Leu->Glu) modified turkey ovomucoid third domain.
CC   -!- Belongs to peptidase family S1E.
PR   PROSITE; PDOC00124;
DR   Q07006, GLUP_STRGR ;
//
ID   3.4.21.83
DE   Oligopeptidase B.
AN   Protease II.
CA   Hydrolysis of -Arg-|-Xaa- and -Lys-|-Xaa- bonds in oligopeptides, even
CA   when P1' residue is proline.
CC   -!- Inhibited by Tos-Lys-CH(2)Cl.
CC   -!- Belongs to peptidase family S9A.
PR   PROSITE; PDOC00587;
DR   P24555, PTRB_ECOLI ;  Q59536, PTRB_MORLA ;
//
ID   3.4.21.84
DE   Limulus clotting factor C.
CA   Selective cleavage of 103-Arg-|-Ser-104 and 124-Ile-|-Ile-125 bonds in
CA   Limulus clotting factor B to form activated factor B. Cleavage of -Pro-
CA   Arg-|-Xaa- bonds in synthetic substrates.
CC   -!- From the hemocyte granules of the horseshoe crabs Limulus and
CC       Tachypleus.
CC   -!- Factor C is activated by Gram-negative bacterial lipopolysaccharides
CC       and chymotrypsin.
CC   -!- Inhibited by antithrombin III.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   Q26422, LFC_CARRO  ;  P28175, LFC_TACTR  ;
//
ID   3.4.21.85
DE   Limulus clotting factor B.
CA   Selective cleavage of 98-Arg-|-Ile-99 bond in Limulus proclotting enzyme
CA   to form active clotting enzyme.
CC   -!- From the hemocyte granules of the horseshoe crabs Limulus and
CC       Tachypleus.
CC   -!- Factor B is activated by factor C.
DR   Q27081, CFB_TACTR  ;
//
ID   3.4.21.86
DE   Limulus clotting enzyme.
CA   Selective cleavage of 18-Arg-|- and 47-Arg-|- bonds in coagulogen to form
CA   coagulin and fragments.
CC   -!- From the hemocyte granules of the horseshoe crabs Limulus and
CC       Tachypleus.
CC   -!- Limulus clotting enzyme is activated by factor B.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   P21902, PCE_TACTR  ;
//
ID   3.4.21.87
DE   Transferred entry: 3.4.23.49.
//
ID   3.4.21.88
DE   Repressor lexA.
CA   Hydrolysis of Ala-|-Gly bond in repressor lexA.
CC   -!- In the presence of single-stranded DNA, the recA protein interacts
CC       with lexA causing an autocatalytic cleavage which disrupts the DNA-
CC       binding part of lexA, leading to derepression of the SOS regulon and
CC       eventually DNA repair.
CC   -!- The activity was previously attributed to the recA protein (formerly
CC       EC 3.4.99.37).
CC   -!- Belongs to peptidase family S24.
DR   P61608, LEXA1_GEOSL;  Q5YP21, LEXA1_NOCFA;  P0A153, LEXA1_PSEPK;
DR   Q87ZB9, LEXA1_PSESM;  Q8PN77, LEXA1_XANAC;  Q8PBM1, LEXA1_XANCP;
DR   Q5GX75, LEXA1_XANOR;  P61609, LEXA2_GEOSL;  Q5YT43, LEXA2_NOCFA;
DR   P59479, LEXA2_PSEPK;  Q881U0, LEXA2_PSESM;  P60511, LEXA2_XANAC;
DR   Q8P9X2, LEXA2_XANCP;  Q5GYM5, LEXA2_XANOR;  A1TQ93, LEXA_ACIAC ;
DR   Q1IU64, LEXA_ACIBL ;  A0LUZ1, LEXA_ACIC1 ;  A5G2J1, LEXA_ACICJ ;
DR   B9MI78, LEXA_ACIET ;  B7JBX0, LEXA_ACIF2 ;  B5EJ91, LEXA_ACIF5 ;
DR   A1W897, LEXA_ACISJ ;  A3N1B4, LEXA_ACTP2 ;  B3GXZ4, LEXA_ACTP7 ;
DR   B0BQ48, LEXA_ACTPJ ;  A6VMQ0, LEXA_ACTSZ ;  Q44069, LEXA_AERHH ;
DR   A4STB3, LEXA_AERS4 ;  B9JEY4, LEXA_AGRRK ;  Q8UFK2, LEXA_AGRT5 ;
DR   B9JX59, LEXA_AGRVS ;  Q0VQU1, LEXA_ALCBS ;  Q0A9N9, LEXA_ALHEH ;
DR   B6ENU0, LEXA_ALISL ;  A6TR70, LEXA_ALKMQ ;  A8MFC9, LEXA_ALKOO ;
DR   B4S1W7, LEXA_ALTMD ;  B8JA57, LEXA_ANAD2 ;  Q2IIJ0, LEXA_ANADE ;
DR   A7HC61, LEXA_ANADF ;  B4UCX8, LEXA_ANASK ;  Q5P4A1, LEXA_AROAE ;
DR   A1R556, LEXA_ARTAT ;  B8HG97, LEXA_ARTCA ;  A0JUZ2, LEXA_ARTS2 ;
DR   A8I825, LEXA_AZOC5 ;  A1K776, LEXA_AZOSB ;  C1DQZ4, LEXA_AZOVD ;
DR   A7Z552, LEXA_BACA2 ;  A0RH75, LEXA_BACAH ;  Q81Y06, LEXA_BACAN ;
DR   B7JIC6, LEXA_BACC0 ;  P61606, LEXA_BACC1 ;  A7GR32, LEXA_BACCN ;
DR   B9IUL2, LEXA_BACCQ ;  Q81A92, LEXA_BACCR ;  Q637D7, LEXA_BACCZ ;
DR   Q9KAD3, LEXA_BACHD ;  Q6HFB0, LEXA_BACHK ;  Q65J42, LEXA_BACLD ;
DR   A8FDP7, LEXA_BACP2 ;  Q5WG03, LEXA_BACSK ;  P31080, LEXA_BACSU ;
DR   A9VPX5, LEXA_BACWK ;  Q6G5D9, LEXA_BARHE ;  Q6FZU5, LEXA_BARQU ;
DR   B2IKM0, LEXA_BEII9 ;  A1A2G3, LEXA_BIFAA ;  B3DQB4, LEXA_BIFLD ;
DR   Q8G4R6, LEXA_BIFLO ;  B7GQ64, LEXA_BIFLS ;  Q2L247, LEXA_BORA1 ;
DR   Q7WCK0, LEXA_BORBR ;  Q7W0T5, LEXA_BORPA ;  A9IR25, LEXA_BORPD ;
DR   Q7VRY0, LEXA_BORPE ;  Q89KS7, LEXA_BRAJA ;  A5EK34, LEXA_BRASB ;
DR   A4YVE6, LEXA_BRASO ;  C0ZES6, LEXA_BREBN ;  B2S5Z4, LEXA_BRUA1 ;
DR   Q2YRR1, LEXA_BRUA2 ;  Q57CZ5, LEXA_BRUAB ;  A9M5F7, LEXA_BRUC2 ;
DR   C0RJB4, LEXA_BRUMB ;  Q8YHG1, LEXA_BRUME ;  A5VQR8, LEXA_BRUO2 ;
DR   B0CGU2, LEXA_BRUSI ;  Q8G0F1, LEXA_BRUSU ;  B1YPM6, LEXA_BURA4 ;
DR   Q1BWH8, LEXA_BURCA ;  B1K0Z6, LEXA_BURCC ;  A0K775, LEXA_BURCH ;
DR   B4E8S4, LEXA_BURCJ ;  Q0BFL9, LEXA_BURCM ;  A9AIX7, LEXA_BURM1 ;
DR   A3MJD2, LEXA_BURM7 ;  A2S339, LEXA_BURM9 ;  Q62K79, LEXA_BURMA ;
DR   A1V472, LEXA_BURMS ;  A3NUV3, LEXA_BURP0 ;  Q3JSP6, LEXA_BURP1 ;
DR   A3N959, LEXA_BURP6 ;  B2JK89, LEXA_BURP8 ;  B2T3L9, LEXA_BURPP ;
DR   Q63TX7, LEXA_BURPS ;  Q39GT3, LEXA_BURS3 ;  Q2SVP7, LEXA_BURTA ;
DR   A4JE56, LEXA_BURVG ;  Q13ZI7, LEXA_BURXL ;  A4XL42, LEXA_CALS8 ;
DR   Q3ACC4, LEXA_CARHZ ;  Q9A724, LEXA_CAUCR ;  B0SYZ8, LEXA_CAUSK ;
DR   B3PEX1, LEXA_CELJU ;  Q1QVT7, LEXA_CHRSD ;  A8AN85, LEXA_CITK8 ;
DR   A5CSL0, LEXA_CLAM3 ;  B0RHB3, LEXA_CLAMS ;  Q97I23, LEXA_CLOAB ;
DR   A7FUK4, LEXA_CLOB1 ;  C3KX30, LEXA_CLOB6 ;  A5I2R7, LEXA_CLOBH ;
DR   C1FNT4, LEXA_CLOBJ ;  B1IM63, LEXA_CLOBK ;  A7GE39, LEXA_CLOBL ;
DR   B1KS97, LEXA_CLOBM ;  B8I2Q1, LEXA_CLOCE ;  Q187P1, LEXA_CLOD6 ;
DR   B9E1Z5, LEXA_CLOK1 ;  A5N8J0, LEXA_CLOK5 ;  A0Q0N2, LEXA_CLONN ;
DR   Q0TRD0, LEXA_CLOP1 ;  Q8XL81, LEXA_CLOPE ;  Q0STQ8, LEXA_CLOPS ;
DR   Q895H6, LEXA_CLOTE ;  A3DDH9, LEXA_CLOTH ;  Q48AA9, LEXA_COLP3 ;
DR   P61607, LEXA_CORDI ;  Q8FPF5, LEXA_COREF ;  A4QET8, LEXA_CORGB ;
DR   Q8NP86, LEXA_CORGL ;  Q4JV87, LEXA_CORJK ;  Q9AGM5, LEXA_CUPNE ;
DR   Q0K9E3, LEXA_CUPNH ;  Q46ZR1, LEXA_CUPPJ ;  B3R2P9, LEXA_CUPTR ;
DR   Q47EP6, LEXA_DECAR ;  O32506, LEXA_DEIRA ;  A9BWH9, LEXA_DELAS ;
DR   B8FIX5, LEXA_DESAA ;  Q314F2, LEXA_DESDG ;  B8FWD3, LEXA_DESHD ;
DR   Q24X76, LEXA_DESHY ;  A4J5P4, LEXA_DESRM ;  A8LMK0, LEXA_DINSH ;
DR   A7ZUR5, LEXA_ECO24 ;  B7UPK4, LEXA_ECO27 ;  B7MJ33, LEXA_ECO45 ;
DR   B7LAZ0, LEXA_ECO55 ;  P0A7C4, LEXA_ECO57 ;  B5Z184, LEXA_ECO5E ;
DR   B7NSK5, LEXA_ECO7I ;  B7N2Q0, LEXA_ECO81 ;  B7M7V6, LEXA_ECO8A ;
DR   C5A136, LEXA_ECOBW ;  B1XC42, LEXA_ECODH ;  A8A7E3, LEXA_ECOHS ;
DR   A1AIM0, LEXA_ECOK1 ;  Q0TA20, LEXA_ECOL5 ;  P0A7C3, LEXA_ECOL6 ;
DR   B1IUK9, LEXA_ECOLC ;  P0A7C2, LEXA_ECOLI ;  B7NFY7, LEXA_ECOLU ;
DR   B6I5Q8, LEXA_ECOSE ;  B1LPK8, LEXA_ECOSM ;  Q1R3P3, LEXA_ECOUT ;
DR   C5B718, LEXA_EDWI9 ;  A4W5F6, LEXA_ENT38 ;  Q834R0, LEXA_ENTFA ;
DR   A7MPP3, LEXA_ENTS8 ;  Q6D9I5, LEXA_ERWCT ;  B2VKA1, LEXA_ERWT9 ;
DR   Q2NA93, LEXA_ERYLH ;  B7LL15, LEXA_ESCF3 ;  B1YE71, LEXA_EXIS2 ;
DR   C4L2T2, LEXA_EXISA ;  B0S1C5, LEXA_FINM2 ;  Q0RDY1, LEXA_FRAAA ;
DR   Q2J779, LEXA_FRASC ;  A8L6K4, LEXA_FRASN ;  B5EA68, LEXA_GEOBB ;
DR   Q5L0C3, LEXA_GEOKA ;  Q39VQ1, LEXA_GEOMG ;  C6DZY8, LEXA_GEOSM ;
DR   C5D9K3, LEXA_GEOSW ;  A4IMK1, LEXA_GEOTN ;  A5GAQ4, LEXA_GEOUR ;
DR   A9HJ64, LEXA_GLUDA ;  Q5FNN8, LEXA_GLUOX ;  Q0BTY8, LEXA_GRABC ;
DR   Q7VNI6, LEXA_HAEDU ;  Q4QME9, LEXA_HAEI8 ;  A5UDX6, LEXA_HAEIE ;
DR   A5UHQ3, LEXA_HAEIG ;  P44858, LEXA_HAEIN ;  B8F317, LEXA_HAEPS ;
DR   Q0I2G7, LEXA_HAES1 ;  B0USF0, LEXA_HAES2 ;  Q2SKC5, LEXA_HAHCH ;
DR   A1WXU3, LEXA_HALHL ;  A9B5H8, LEXA_HERA2 ;  A4G713, LEXA_HERAR ;
DR   Q0C1A3, LEXA_HYPNA ;  Q5QUP5, LEXA_IDILO ;  A6SXJ3, LEXA_JANMA ;
DR   Q28R71, LEXA_JANSC ;  B5XXY9, LEXA_KLEP3 ;  A6TGV2, LEXA_KLEP7 ;
DR   Q5FJL4, LEXA_LACAC ;  Q03B55, LEXA_LACC3 ;  B3WC17, LEXA_LACCB ;
DR   Q1G9M5, LEXA_LACDA ;  Q049T1, LEXA_LACDB ;  B2GBL2, LEXA_LACF3 ;
DR   Q044D8, LEXA_LACGA ;  A8YVS7, LEXA_LACH4 ;  P61610, LEXA_LACJO ;
DR   Q88VI6, LEXA_LACPL ;  A5VJB8, LEXA_LACRD ;  B2G6T4, LEXA_LACRJ ;
DR   Q1WUI6, LEXA_LACS1 ;  Q38W54, LEXA_LACSS ;  Q6AE10, LEXA_LEIXX ;
DR   B0SFV4, LEXA_LEPBA ;  Q04RH1, LEXA_LEPBJ ;  Q053A1, LEXA_LEPBL ;
DR   B0SPA2, LEXA_LEPBP ;  B1Y250, LEXA_LEPCP ;  P61611, LEXA_LEPIC ;
DR   Q8F663, LEXA_LEPIN ;  B1MZ70, LEXA_LEUCK ;  Q03WX0, LEXA_LEUMM ;
DR   Q92C51, LEXA_LISIN ;  C1L2K9, LEXA_LISMC ;  Q720B9, LEXA_LISMF ;
DR   B8DG25, LEXA_LISMH ;  Q8Y7H7, LEXA_LISMO ;  A0AIA3, LEXA_LISW6 ;
DR   B1HRJ5, LEXA_LYSSC ;  Q2W3A5, LEXA_MAGSA ;  A0L9E2, LEXA_MAGSM ;
DR   Q65UK9, LEXA_MANSM ;  A1U269, LEXA_MARAV ;  Q0APU7, LEXA_MARMM ;
DR   A6VX60, LEXA_MARMS ;  Q11HT8, LEXA_MESSB ;  Q605V8, LEXA_METCA ;
DR   B8IN87, LEXA_METNO ;  A2SGY5, LEXA_METPP ;  B1LUJ7, LEXA_METRJ ;
DR   B0UGH4, LEXA_METS4 ;  B8EK86, LEXA_METSB ;  Q2RJF5, LEXA_MOOTA ;
DR   A0QIQ3, LEXA_MYCA1 ;  B1MCZ5, LEXA_MYCA9 ;  Q7TY15, LEXA_MYCBO ;
DR   A1KM58, LEXA_MYCBP ;  C1AFH9, LEXA_MYCBT ;  A4TCN9, LEXA_MYCGI ;
DR   B8ZQU5, LEXA_MYCLB ;  Q49848, LEXA_MYCLE ;  B2HLX8, LEXA_MYCMM ;
DR   P61612, LEXA_MYCPA ;  A0QVY5, LEXA_MYCS2 ;  A3PYG6, LEXA_MYCSJ ;
DR   A1UF04, LEXA_MYCSK ;  Q1BA08, LEXA_MYCSS ;  A5U672, LEXA_MYCTA ;
DR   Q50765, LEXA_MYCTU ;  A0PT76, LEXA_MYCUA ;  A1T7V4, LEXA_MYCVP ;
DR   Q1D406, LEXA_MYXXD ;  Q1QMK3, LEXA_NITHX ;  Q3SRJ0, LEXA_NITWN ;
DR   A1SND2, LEXA_NOCSJ ;  Q2G6Q5, LEXA_NOVAD ;  Q8EQM5, LEXA_OCEIH ;
DR   A6X0K7, LEXA_OCHA4 ;  Q04F93, LEXA_OENOB ;  B6JG34, LEXA_OLICO ;
DR   A1B3Z0, LEXA_PARDP ;  A7HY01, LEXA_PARL1 ;  P57917, LEXA_PASMU ;
DR   Q04596, LEXA_PECCC ;  C6DKD2, LEXA_PECCP ;  Q03FU3, LEXA_PEDPA ;
DR   Q3A3S5, LEXA_PELCD ;  A5D2J8, LEXA_PELTS ;  Q4FM55, LEXA_PELUB ;
DR   A9BGA3, LEXA_PETMO ;  B4RBX6, LEXA_PHEZH ;  Q7MZB8, LEXA_PHOLL ;
DR   Q6LVS1, LEXA_PHOPR ;  A1VNK0, LEXA_POLNA ;  Q129C4, LEXA_POLSJ ;
DR   B4EYR3, LEXA_PROMH ;  Q07267, LEXA_PRORE ;  Q15MZ2, LEXA_PSEA6 ;
DR   A6V389, LEXA_PSEA7 ;  B7UYS3, LEXA_PSEA8 ;  Q02PH1, LEXA_PSEAB ;
DR   P37452, LEXA_PSEAE ;  Q8KT78, LEXA_PSECL ;  A4XSN5, LEXA_PSEMY ;
DR   P0A154, LEXA_PSEPU ;  A1SR67, LEXA_PSYIN ;  Q1LLW6, LEXA_RALME ;
DR   B2UAG1, LEXA_RALPJ ;  Q8XZU1, LEXA_RALSO ;  B3PYQ7, LEXA_RHIE6 ;
DR   Q2K8X2, LEXA_RHIEC ;  Q1MH39, LEXA_RHIL3 ;  Q98MD2, LEXA_RHILO ;
DR   B5ZN98, LEXA_RHILW ;  Q92PW3, LEXA_RHIME ;  P61605, LEXA_RHIRD ;
DR   P61613, LEXA_RHOCA ;  B6IST2, LEXA_RHOCS ;  Q21U48, LEXA_RHOFD ;
DR   Q2IW99, LEXA_RHOP2 ;  Q07NH5, LEXA_RHOP5 ;  P61614, LEXA_RHOPA ;
DR   Q215D1, LEXA_RHOPB ;  Q136C2, LEXA_RHOPS ;  B3Q6P2, LEXA_RHOPT ;
DR   Q2RT47, LEXA_RHORT ;  A3PHK4, LEXA_RHOS1 ;  Q9ZFA4, LEXA_RHOS4 ;
DR   A4WX64, LEXA_RHOS5 ;  Q163X5, LEXA_ROSDO ;  A5UQF5, LEXA_ROSS1 ;
DR   Q21JT2, LEXA_SACD2 ;  B5F1Q6, LEXA_SALA4 ;  A9MGP6, LEXA_SALAR ;
DR   Q57GZ0, LEXA_SALCH ;  B5FQR1, LEXA_SALDC ;  B5QZ62, LEXA_SALEP ;
DR   B5R7T6, LEXA_SALG2 ;  B4TDM0, LEXA_SALHS ;  B4T1T2, LEXA_SALNS ;
DR   Q5PL14, LEXA_SALPA ;  A9N1L6, LEXA_SALPB ;  C0Q514, LEXA_SALPC ;
DR   B5BJW0, LEXA_SALPK ;  B4TQQ5, LEXA_SALSV ;  P0A274, LEXA_SALTI ;
DR   P0A273, LEXA_SALTY ;  A8GKB4, LEXA_SERP5 ;  A1SBC7, LEXA_SHEAM ;
DR   B8ECL9, LEXA_SHEB2 ;  A3CYX7, LEXA_SHEB5 ;  A6WU05, LEXA_SHEB8 ;
DR   A9KUW8, LEXA_SHEB9 ;  Q12ID6, LEXA_SHEDO ;  Q089E2, LEXA_SHEFN ;
DR   B0TNT3, LEXA_SHEHH ;  A3Q951, LEXA_SHELP ;  Q8E8Q8, LEXA_SHEON ;
DR   A8H9S0, LEXA_SHEPA ;  A4YC04, LEXA_SHEPC ;  B8CUX0, LEXA_SHEPW ;
DR   A0L2D8, LEXA_SHESA ;  A8FPP0, LEXA_SHESH ;  Q0HDL5, LEXA_SHESM ;
DR   Q0HPW6, LEXA_SHESR ;  A1RE93, LEXA_SHESW ;  B1KM68, LEXA_SHEWM ;
DR   B2TX73, LEXA_SHIB3 ;  Q31TV1, LEXA_SHIBS ;  Q327V0, LEXA_SHIDS ;
DR   Q0SXR0, LEXA_SHIF8 ;  P0A7C5, LEXA_SHIFL ;  Q3YUU1, LEXA_SHISS ;
DR   Q5LRH4, LEXA_SILPO ;  Q1GHJ8, LEXA_SILST ;  A6U971, LEXA_SINMW ;
DR   Q2NR09, LEXA_SODGM ;  A9F881, LEXA_SORC5 ;  Q1GUX2, LEXA_SPHAL ;
DR   A5VB97, LEXA_SPHWW ;  A7X1Z4, LEXA_STAA1 ;  Q2FH94, LEXA_STAA3 ;
DR   Q2FYU1, LEXA_STAA8 ;  Q2YXS8, LEXA_STAAB ;  Q9L4P1, LEXA_STAAC ;
DR   A6QGP1, LEXA_STAAE ;  P65819, LEXA_STAAM ;  P65820, LEXA_STAAN ;
DR   Q6GH67, LEXA_STAAR ;  Q6G9L9, LEXA_STAAS ;  Q93SM0, LEXA_STAAW ;
DR   B9DP69, LEXA_STACT ;  Q5HPK2, LEXA_STAEQ ;  Q4L648, LEXA_STAHJ ;
DR   Q49XD4, LEXA_STAS1 ;  Q82KE0, LEXA_STRAW ;  O86847, LEXA_STRCL ;
DR   O69979, LEXA_STRCO ;  B4SRA9, LEXA_STRM5 ;  Q67NM2, LEXA_SYMTH ;
DR   A0LGS1, LEXA_SYNFM ;  Q0AY82, LEXA_SYNWW ;  C5BIH2, LEXA_TERTT ;
DR   B7IDD1, LEXA_THEAB ;  Q47MY4, LEXA_THEFY ;  A8F429, LEXA_THELT ;
DR   A6LM87, LEXA_THEM4 ;  O33927, LEXA_THEMA ;  O86948, LEXA_THENE ;
DR   B9K9N0, LEXA_THENN ;  A5IN94, LEXA_THEP1 ;  B1L838, LEXA_THESQ ;
DR   Q3SIT9, LEXA_THIDA ;  C4L7X7, LEXA_TOLAT ;  C5CKV7, LEXA_VARPS ;
DR   A1WSJ3, LEXA_VEREI ;  A5F4F6, LEXA_VIBC3 ;  Q9KVP9, LEXA_VIBCH ;
DR   C3LPT4, LEXA_VIBCM ;  Q5E209, LEXA_VIBF1 ;  B5FCB2, LEXA_VIBFM ;
DR   A7N0W6, LEXA_VIBHB ;  Q87KN2, LEXA_VIBPA ;  B7VM94, LEXA_VIBSL ;
DR   Q8DD47, LEXA_VIBVU ;  Q7MQ85, LEXA_VIBVY ;  Q93MQ9, LEXA_XANCA ;
DR   P60512, LEXA_XANCI ;  A7INJ8, LEXA_XANP2 ;  B2I679, LEXA_XYLF2 ;
DR   Q9PH24, LEXA_XYLFA ;  B0U1K7, LEXA_XYLFM ;  Q87F45, LEXA_XYLFT ;
DR   A1JRT9, LEXA_YERE8 ;  A7FN96, LEXA_YERP3 ;  Q1C0U1, LEXA_YERPA ;
DR   B2K1U7, LEXA_YERPB ;  Q8ZJ16, LEXA_YERPE ;  A9R273, LEXA_YERPG ;
DR   Q1CE98, LEXA_YERPN ;  A4TRU5, LEXA_YERPP ;  Q66FG7, LEXA_YERPS ;
DR   B1JNE3, LEXA_YERPY ;  Q5NR31, LEXA_ZYMMO ;
//
ID   3.4.21.89
DE   Signal peptidase I.
AN   Bacterial leader peptidase I.
AN   Phage-procoat-leader peptidase.
AN   SPase I.
CA   Cleavage of hydrophobic, N-terminal signal or leader sequences from
CA   secreted and periplasmic proteins.
CC   -!- Unaffected by inhibitors of most serine peptidases, but site-directed
CC       mutagenesis implicates a Ser/Lys catalytic dyad in activity.
CC   -!- Cleaves a single bond -Ala-|-Ala- in M13 phage procoat protein,
CC       producing free signal peptide and coat protein.
CC   -!- Eukaryote signal peptidases that may have somewhat different
CC       specificity are known from the endoplasmic reticulum membrane and
CC       mitochondrial inner membrane.
CC   -!- Belongs to peptidase family S26.
CC   -!- Formerly EC 3.4.99.36.
PR   PROSITE; PDOC00418;
DR   P41026, LEP1_BACAM ;  P72660, LEP1_SYNY3 ;  P41025, LEP2_BACAM ;
DR   P73157, LEP2_SYNY3 ;  P37943, LEPP_BACNA ;  Q57350, LEPQ_BACNA ;
DR   P28628, LEPS_BACSU ;  P71013, LEPT_BACSU ;  P42959, LEPU_BACSU ;
DR   O07560, LEPV_BACSU ;  P54506, LEPW_BACSU ;  O67088, LEP_AQUAE  ;
DR   P41027, LEP_BACCL  ;  P42668, LEP_BACLI  ;  P57347, LEP_BUCAI  ;
DR   Q8K9R0, LEP_BUCAP  ;  Q89AM6, LEP_BUCBP  ;  P00803, LEP_ECOLI  ;
DR   P44454, LEP_HAEIN  ;  Q9ZLQ5, LEP_HELPJ  ;  O25300, LEP_HELPY  ;
DR   O33021, LEP_MYCLE  ;  Q10789, LEP_MYCTU  ;  Q51876, LEP_PHOLA  ;
DR   Q9I5G7, LEP_PSEAE  ;  P26844, LEP_PSEFL  ;  A8GM78, LEP_RICAH  ;
DR   A8GYE1, LEP_RICB8  ;  Q1RHA1, LEP_RICBR  ;  A8EXI2, LEP_RICCK  ;
DR   Q92JB1, LEP_RICCN  ;  Q4UKA7, LEP_RICFE  ;  A8F0M1, LEP_RICM5  ;
DR   Q9ZE32, LEP_RICPR  ;  A8GQT7, LEP_RICRS  ;  Q8L2J7, LEP_RICTY  ;
DR   P0A1W3, LEP_SALTI  ;  P0A1W2, LEP_SALTY  ;  Q5HHB9, LEP_STAAC  ;
DR   P0A067, LEP_STAAM  ;  P0A068, LEP_STAAN  ;  Q6GIC3, LEP_STAAR  ;
DR   Q6GAW1, LEP_STAAS  ;  P0A070, LEP_STAAU  ;  P0A069, LEP_STAAW  ;
DR   O07344, LEP_STRPN  ;  P59662, LEP_STRR6  ;  Q8H0W1, PLSP1_ARATH;
DR   P67810, SC11A_BOVIN;  P67811, SC11A_CANFA;  P67812, SC11A_HUMAN;
DR   Q9R0P6, SC11A_MOUSE;  Q5R9C7, SC11A_PONAB;  P42667, SC11A_RAT  ;
DR   P0C7V7, SC11B_HUMAN;  P13679, SC11C_CANFA;  Q9BY50, SC11C_HUMAN;
DR   Q9D8V7, SC11C_MOUSE;  Q5RC30, SC11C_PONAB;  Q9WTR7, SC11C_RAT  ;
DR   F0UDD2, SEC11_AJEC8;  C0NKT8, SEC11_AJECG;  C6HB29, SEC11_AJECH;
DR   A6QX24, SEC11_AJECN;  C5G8L5, SEC11_AJEDR;  C5JJG5, SEC11_AJEDS;
DR   D4ALL0, SEC11_ARTBC;  E4V4X0, SEC11_ARTGP;  C5FQ45, SEC11_ARTOC;
DR   Q759W4, SEC11_ASHGO;  A1CL29, SEC11_ASPCL;  B0XWT3, SEC11_ASPFC;
DR   Q4WYF4, SEC11_ASPFU;  Q2UBW3, SEC11_ASPOR;  Q0CQC5, SEC11_ASPTN;
DR   Q5A869, SEC11_CANAL;  C4YNJ0, SEC11_CANAW;  B9WKT4, SEC11_CANDC;
DR   C5M4J6, SEC11_CANTT;  Q2H1P3, SEC11_CHAGB;  C4Y3D4, SEC11_CLAL4;
DR   C5PA33, SEC11_COCP7;  E9CXH2, SEC11_COCPS;  E3QXY4, SEC11_COLGM;
DR   Q6BP15, SEC11_DEBHA;  Q86JD4, SEC11_DICDI;  Q5B8K4, SEC11_EMENI;
DR   F0XJH4, SEC11_GROCL;  Q6CMR5, SEC11_KLULA;  B0D4L0, SEC11_LACBS;
DR   C5DDH1, SEC11_LACTC;  E5A8D2, SEC11_LEPMJ;  A5DS09, SEC11_LODEL;
DR   A4RGA1, SEC11_MAGO7;  E9E796, SEC11_METAQ;  E9F8V9, SEC11_METAR;
DR   C7ZHK5, SEC11_NECH7;  A1D6D8, SEC11_NEOFI;  Q7RY44, SEC11_NEUCR;
DR   C1GU90, SEC11_PARBA;  C1FYD2, SEC11_PARBD;  C0S3S0, SEC11_PARBP;
DR   B6HC89, SEC11_PENCW;  B6Q5G0, SEC11_PENMQ;  E7R7C4, SEC11_PICAD;
DR   A5DIZ8, SEC11_PICGU;  C4QXP7, SEC11_PICPG;  A3LXS1, SEC11_PICST;
DR   B2B3T2, SEC11_PODAN;  B2WEL2, SEC11_PYRTR;  E3RR70, SEC11_PYRTT;
DR   D8Q7Q5, SEC11_SCHCM;  O74323, SEC11_SCHPO;  A7E716, SEC11_SCLS1;
DR   B8M5K5, SEC11_TALSN;  D4D5I1, SEC11_TRIVH;  D5GNC3, SEC11_TUBMM;
DR   C4JYM4, SEC11_UNCRE;  C9S8G0, SEC11_VERA1;  Q6CAG9, SEC11_YARLI;
DR   B3LTI7, SEC11_YEAS1;  C7GLT4, SEC11_YEAS2;  A6ZVU2, SEC11_YEAS7;
DR   C8ZAS4, SEC11_YEAS8;  E7KDY6, SEC11_YEASA;  E7Q587, SEC11_YEASB;
DR   E7KQ01, SEC11_YEASL;  P15367, SEC11_YEAST;  E7LVX4, SEC11_YEASV;
DR   E7QG89, SEC11_YEASZ;  C5E3W1, SEC11_ZYGRC;  O04348, TPP1_ARATH ;
DR   Q9M9Z2, TPP2_ARATH ;
//
ID   3.4.21.90
DE   Togavirin.
AN   NsP2 proteinase.
AN   Sindbis virus protease.
CA   Autocatalytic release of the core protein from the N-terminus of the
CA   togavirus structural polyprotein by hydrolysis of a -Trp-|-Ser- bond.
CC   -!- Once released, the core protein does not retain catalytic activity.
CC   -!- Belongs to peptidase family S3.
DR   Q86925, POLS_AURAV ;  P89946, POLS_BFV   ;  Q5XXP3, POLS_CHIK3 ;
DR   Q5WQY5, POLS_CHIKN ;  Q8JUX5, POLS_CHIKS ;  P08768, POLS_EEEV  ;
DR   Q306W5, POLS_EEEV1 ;  P27284, POLS_EEEV3 ;  Q306W7, POLS_EEEV8 ;
DR   Q4QXJ7, POLS_EEEVF ;  P36329, POLS_EEVV3 ;  P05674, POLS_EEVV8 ;
DR   P36330, POLS_EEVVE ;  P36331, POLS_EEVVM ;  P36332, POLS_EEVVP ;
DR   P09592, POLS_EEVVT ;  Q5Y388, POLS_GETV  ;  Q8QZ72, POLS_MAYAB ;
DR   P22056, POLS_ONNVG ;  O90371, POLS_ONNVI ;  O90369, POLS_ONNVS ;
DR   P13890, POLS_RRVN  ;  P08491, POLS_RRVT  ;  Q9JGK8, POLS_SAGV  ;
DR   P03315, POLS_SFV   ;  P27285, POLS_SINDO ;  P03316, POLS_SINDV ;
DR   P13897, POLS_WEEV  ;
//
ID   3.4.21.91
DE   Flavivirin.
AN   NS2B-3 proteinase.
AN   Yellow fever virus protease.
CA   Selective hydrolysis of -Xaa-Xaa-|-Yaa- bonds in which each of the Xaa
CA   can be either Arg or Lys and Yaa can be either Ser or Ala.
DR   P27909, POLG_DEN1B ;  P33478, POLG_DEN1S ;  P17763, POLG_DEN1W ;
DR   P29990, POLG_DEN26 ;  P29991, POLG_DEN27 ;  P14337, POLG_DEN28 ;
DR   P07564, POLG_DEN2J ;  P14340, POLG_DEN2N ;  P12823, POLG_DEN2P ;
DR   Q9WDA6, POLG_DEN2Q ;  P27914, POLG_DEN2T ;  Q99D35, POLG_DEN3C ;
DR   Q5UB51, POLG_DEN3I ;  Q6YMS3, POLG_DEN3M ;  P27915, POLG_DEN3P ;
DR   Q6YMS4, POLG_DEN3S ;  P09866, POLG_DEN4D ;  Q2YHF2, POLG_DEN4H ;
DR   Q58HT7, POLG_DEN4P ;  Q5UCB8, POLG_DEN4S ;  Q2YHF0, POLG_DEN4T ;
DR   P27395, POLG_JAEV1 ;  P19110, POLG_JAEV5 ;  P32886, POLG_JAEVJ ;
DR   P14403, POLG_JAEVN ;  P14335, POLG_KUNJM ;  P29837, POLG_LANVT ;
DR   P22338, POLG_LIV   ;  P33515, POLG_MCFA  ;  P05769, POLG_MVEV5 ;
DR   Q04538, POLG_POWVL ;  P09732, POLG_STEVM ;  Q01299, POLG_TBEVH ;
DR   P07720, POLG_TBEVS ;  P14336, POLG_TBEVW ;  P06935, POLG_WNV   ;
DR   P03314, POLG_YEFV1 ;  Q6DV88, POLG_YEFVA ;  Q6J3P1, POLG_YEFVC ;
DR   Q074N0, POLG_YEFVE ;  Q89277, POLG_YEFVF ;  Q98803, POLG_YEFVI ;
DR   Q1X881, POLG_YEFVN ;  Q9YRV3, POLG_YEFVT ;  Q1X880, POLG_YEFVU ;
//
ID   3.4.21.92
DE   Endopeptidase Clp.
AN   Caseinolytic protease.
AN   Endopeptidase Ti.
AN   Protease Ti.
CA   Hydrolysis of proteins to small peptides in the presence of ATP and
CA   magnesium. Alpha-casein is the usual test substrate. In the absence of
CA   ATP, only oligopeptides shorter than five residues are hydrolyzed (such
CA   as succinyl-Leu-Tyr-|-NHMec; and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage
CA   of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs).
CC   -!- Belongs to peptidase family S14.
PR   PROSITE; PDOC00358;
DR   Q8UEX6, CLPP1_AGRT5;  Q3MFR5, CLPP1_ANAVT;  P56772, CLPP1_ARATH;
DR   Q81PL4, CLPP1_BACAN;  Q736T1, CLPP1_BACC1;  Q81CH1, CLPP1_BACCR;
DR   Q63AG0, CLPP1_BACCZ;  Q9K709, CLPP1_BACHD;  Q6HHU9, CLPP1_BACHK;
DR   Q65EI5, CLPP1_BACLD;  Q5WLZ7, CLPP1_BACSK;  Q8G5R0, CLPP1_BIFLO;
DR   O51556, CLPP1_BORBU;  Q89WR7, CLPP1_BRAJA;  Q13UT1, CLPP1_BURXL;
DR   A8WPG6, CLPP1_CAEBR;  Q27539, CLPP1_CAEEL;  Q5L6P3, CLPP1_CHLAB;
DR   Q824C7, CLPP1_CHLCV;  Q256C2, CLPP1_CHLFF;  Q9PJW1, CLPP1_CHLMU;
DR   Q9Z832, CLPP1_CHLPN;  B0B803, CLPP1_CHLT2;  Q3KLR9, CLPP1_CHLTA;
DR   P38002, CLPP1_CHLTR;  Q6NFU5, CLPP1_CORDI;  Q8FN37, CLPP1_COREF;
DR   Q8NN02, CLPP1_CORGL;  Q4JWV4, CLPP1_CORJK;  Q36863, CLPP1_CYAPA;
DR   Q250C6, CLPP1_DESHY;  Q2JDQ9, CLPP1_FRASC;  Q7NEW2, CLPP1_GLOVI;
DR   Q5FUR3, CLPP1_GLUOX;  Q6AFZ8, CLPP1_LEIXX;  Q72SG6, CLPP1_LEPIC;
DR   Q11J60, CLPP1_MESSB;  Q60C68, CLPP1_METCA;  P0A527, CLPP1_MYCBO;
DR   Q9CBY3, CLPP1_MYCLE;  Q73XM9, CLPP1_MYCPA;  P0A526, CLPP1_MYCTU;
DR   Q1DAT0, CLPP1_MYXXD;  Q5Z0M4, CLPP1_NOCFA;  Q8YXH5, CLPP1_NOSS1;
DR   Q6ME32, CLPP1_PARUW;  Q6A7F0, CLPP1_PROAC;  Q31BD5, CLPP1_PROM9;
DR   Q7VC22, CLPP1_PROMA;  Q7V992, CLPP1_PROMM;  Q7V1W0, CLPP1_PROMP;
DR   Q46L44, CLPP1_PROMT;  Q9I2U1, CLPP1_PSEAE;  Q2KAB9, CLPP1_RHIEC;
DR   Q1MK43, CLPP1_RHIL3;  Q98M38, CLPP1_RHILO;  P58277, CLPP1_RHIME;
DR   Q7UK67, CLPP1_RHOBA;  Q0SGZ1, CLPP1_RHOSR;  Q2S2L8, CLPP1_SALRD;
DR   Q82NZ4, CLPP1_STRAW;  Q9F315, CLPP1_STRCO;  Q67SK0, CLPP1_SYMTH;
DR   P54415, CLPP1_SYNE7;  Q2JWJ1, CLPP1_SYNJA;  Q2JHM1, CLPP1_SYNJB;
DR   Q5N665, CLPP1_SYNP6;  Q7UA36, CLPP1_SYNPX;  Q3AY04, CLPP1_SYNS9;
DR   Q3ANI8, CLPP1_SYNSC;  P54416, CLPP1_SYNY3;  Q8DLI2, CLPP1_THEEB;
DR   Q47MU3, CLPP1_THEFY;  Q73M38, CLPP1_TREDE;  O83520, CLPP1_TREPA;
DR   Q83I19, CLPP1_TROW8;  Q83G49, CLPP1_TROWT;  Q8UFY6, CLPP2_AGRT5;
DR   Q3MDK7, CLPP2_ANAVT;  Q9FN42, CLPP2_ARATH;  Q81X63, CLPP2_BACAN;
DR   Q72XW9, CLPP2_BACC1;  Q815J6, CLPP2_BACCR;  Q631K2, CLPP2_BACCZ;
DR   Q9K888, CLPP2_BACHD;  Q6HBD8, CLPP2_BACHK;  Q65E10, CLPP2_BACLD;
DR   Q5WDK0, CLPP2_BACSK;  Q8G5Q9, CLPP2_BIFLO;  O51698, CLPP2_BORBU;
DR   Q89KG1, CLPP2_BRAJA;  Q13Z15, CLPP2_BURXL;  Q5L4W7, CLPP2_CHLAB;
DR   Q821M0, CLPP2_CHLCV;  Q253I5, CLPP2_CHLFF;  Q9PLM0, CLPP2_CHLMU;
DR   Q9Z759, CLPP2_CHLPN;  Q3KKY8, CLPP2_CHLTA;  O84712, CLPP2_CHLTR;
DR   Q6NFU4, CLPP2_CORDI;  Q8FN36, CLPP2_COREF;  Q8NN01, CLPP2_CORGL;
DR   Q4JWV3, CLPP2_CORJK;  Q24S49, CLPP2_DESHY;  Q2JDQ8, CLPP2_FRASC;
DR   Q7NEW1, CLPP2_GLOVI;  Q5FQT4, CLPP2_GLUOX;  Q6AFZ7, CLPP2_LEIXX;
DR   Q72R01, CLPP2_LEPIC;  Q11I48, CLPP2_MESSB;  Q60BE8, CLPP2_METCA;
DR   P63784, CLPP2_MYCBO;  Q9CBY4, CLPP2_MYCLE;  Q73XM8, CLPP2_MYCPA;
DR   P63783, CLPP2_MYCTU;  Q9X5N0, CLPP2_MYXXA;  O30612, CLPP2_MYXXD;
DR   Q5Z063, CLPP2_NOCFA;  Q8YQX8, CLPP2_NOSS1;  Q6MBE9, CLPP2_PARUW;
DR   Q6A7E9, CLPP2_PROAC;  Q319H4, CLPP2_PROM9;  Q7VAR9, CLPP2_PROMA;
DR   Q7V8M4, CLPP2_PROMM;  Q7V0F1, CLPP2_PROMP;  Q46JF7, CLPP2_PROMT;
DR   Q9HYR9, CLPP2_PSEAE;  Q2K9U7, CLPP2_RHIEC;  Q1MIM7, CLPP2_RHIL3;
DR   Q982V6, CLPP2_RHILO;  P58278, CLPP2_RHIME;  Q7UK66, CLPP2_RHOBA;
DR   Q0SGZ0, CLPP2_RHOSR;  Q2RZ59, CLPP2_SALRD;  Q82NZ3, CLPP2_STRAW;
DR   Q9ZH58, CLPP2_STRCO;  Q67QZ4, CLPP2_SYMTH;  O34125, CLPP2_SYNE7;
DR   Q2JV68, CLPP2_SYNJA;  Q2JIP1, CLPP2_SYNJB;  Q5N1Q7, CLPP2_SYNP6;
DR   Q7U6N7, CLPP2_SYNPX;  Q3B0U1, CLPP2_SYNS9;  Q3AJN8, CLPP2_SYNSC;
DR   Q59993, CLPP2_SYNY3;  Q8DJZ9, CLPP2_THEEB;  Q47MU2, CLPP2_THEFY;
DR   Q73JM9, CLPP2_TREDE;  O84003, CLPP2_TREPA;  Q83I18, CLPP2_TROW8;
DR   Q83G48, CLPP2_TROWT;  Q8UD57, CLPP3_AGRT5;  Q3M726, CLPP3_ANAVT;
DR   Q9SXJ6, CLPP3_ARATH;  Q2J9A9, CLPP3_FRASC;  Q5Z062, CLPP3_NOCFA;
DR   Q8YP43, CLPP3_NOSS1;  Q7V9L6, CLPP3_PROMA;  Q7V7R2, CLPP3_PROMM;
DR   Q7UZK7, CLPP3_PROMP;  Q46ID4, CLPP3_PROMT;  Q2K5Q0, CLPP3_RHIEC;
DR   Q1MDH4, CLPP3_RHIL3;  Q9X7L1, CLPP3_RHIME;  Q0SGJ7, CLPP3_RHOSR;
DR   Q82CA6, CLPP3_STRAW;  Q9X7R9, CLPP3_STRCO;  Q9L4P3, CLPP3_SYNE7;
DR   Q5N1P6, CLPP3_SYNP6;  Q7U5Q2, CLPP3_SYNPX;  Q3AVC3, CLPP3_SYNS9;
DR   Q3ALC4, CLPP3_SYNSC;  P74467, CLPP3_SYNY3;  Q94B60, CLPP4_ARATH;
DR   Q2J9A8, CLPP4_FRASC;  Q317Y6, CLPP4_PROM9;  Q0SGJ6, CLPP4_RHOSR;
DR   Q82CA5, CLPP4_STRAW;  Q9S834, CLPP5_ARATH;  Q826S4, CLPP5_STRAW;
DR   Q9SAA2, CLPP6_ARATH;  P84982, CLPPH_POPEU;  A1TM62, CLPP_ACIAC ;
DR   Q6FEP8, CLPP_ACIAD ;  Q1IRD8, CLPP_ACIBL ;  C1F6W4, CLPP_ACIC5 ;
DR   B9MG14, CLPP_ACIET ;  A1W5B6, CLPP_ACISJ ;  Q3V509, CLPP_ACOCL ;
DR   Q5QA83, CLPP_ACOGR ;  A3N1T0, CLPP_ACTP2 ;  B3H252, CLPP_ACTP7 ;
DR   B0BQL3, CLPP_ACTPJ ;  A6VME1, CLPP_ACTSZ ;  Q85FJ8, CLPP_ADICA ;
DR   A4SM42, CLPP_AERS4 ;  A4QJE0, CLPP_AETCO ;  A4QJM4, CLPP_AETGR ;
DR   A1EA33, CLPP_AGRST ;  Q0VQ90, CLPP_ALCBS ;  Q0A6A7, CLPP_ALHEH ;
DR   B6EHK3, CLPP_ALISL ;  A6TM61, CLPP_ALKMQ ;  A8MIS8, CLPP_ALKOO ;
DR   Q70XY2, CLPP_AMBTC ;  B8J5G7, CLPP_ANAD2 ;  Q2IEW1, CLPP_ANADE ;
DR   A7HFV9, CLPP_ANADF ;  B9KHZ4, CLPP_ANAMF ;  Q5PBD0, CLPP_ANAMM ;
DR   Q2GJB4, CLPP_ANAPZ ;  B4UAX9, CLPP_ANASK ;  A2T358, CLPP_ANGEV ;
DR   B7GL34, CLPP_ANOFW ;  Q85BZ1, CLPP_ANTFO ;  O67357, CLPP_AQUAE ;
DR   A4QK43, CLPP_ARAHI ;  A8EVH5, CLPP_ARCB4 ;  Q5P161, CLPP_AROAE ;
DR   Q8S8W2, CLPP_ATRBE ;  Q9X6W8, CLPP_AZOBR ;  A8HYF2, CLPP_AZOC5 ;
DR   A1K783, CLPP_AZOSB ;  A7Z939, CLPP_BACA2 ;  Q5L8L6, CLPP_BACFN ;
DR   Q64NW2, CLPP_BACFR ;  A8FHN9, CLPP_BACP2 ;  P80244, CLPP_BACSU ;
DR   Q8A129, CLPP_BACTN ;  A1USA7, CLPP_BARBK ;  Q6G3Z3, CLPP_BARHE ;
DR   Q6G178, CLPP_BARQU ;  A9ISA4, CLPP_BART1 ;  A4QKD0, CLPP_BARVE ;
DR   Q1LTJ9, CLPP_BAUCH ;  Q6MH11, CLPP_BDEBA ;  Q06J25, CLPP_BIGNA ;
DR   Q7VRH1, CLPP_BLOFL ;  Q493F8, CLPP_BLOPB ;  Q2L256, CLPP_BORA1 ;
DR   Q0SMP6, CLPP_BORAP ;  Q7WK83, CLPP_BORBR ;  Q660R2, CLPP_BORGA ;
DR   Q7W8X2, CLPP_BORPA ;  A9IR54, CLPP_BORPD ;  Q7VXI7, CLPP_BORPE ;
DR   Q2KHU4, CLPP_BOVIN ;  C0QW91, CLPP_BRAHW ;  A5EKA8, CLPP_BRASB ;
DR   B2S5W1, CLPP_BRUA1 ;  Q2YPX1, CLPP_BRUA2 ;  Q9L7X6, CLPP_BRUAB ;
DR   A9M5C2, CLPP_BRUC2 ;  C0RJ81, CLPP_BRUMB ;  Q8YHC8, CLPP_BRUME ;
DR   B0CGR1, CLPP_BRUSI ;  Q8G0I4, CLPP_BRUSU ;  P57547, CLPP_BUCAI ;
DR   Q8K990, CLPP_BUCAP ;  Q89AA1, CLPP_BUCBP ;  Q1BH85, CLPP_BURCA ;
DR   A0K847, CLPP_BURCH ;  Q0BEF6, CLPP_BURCM ;  A3MKJ8, CLPP_BURM7 ;
DR   A2SBG3, CLPP_BURM9 ;  Q62JK7, CLPP_BURMA ;  A1V4X1, CLPP_BURMS ;
DR   A3NWA6, CLPP_BURP0 ;  Q3JRC9, CLPP_BURP1 ;  A3NAI5, CLPP_BURP6 ;
DR   Q63V41, CLPP_BURPS ;  Q39FE8, CLPP_BURS3 ;  Q2SWQ6, CLPP_BURTA ;
DR   A4JF05, CLPP_BURVG ;  A6MM61, CLPP_BUXMI ;  Q7YJV2, CLPP_CALFG ;
DR   A4XHW0, CLPP_CALS8 ;  A7HZE8, CLPP_CAMHC ;  A8FJZ3, CLPP_CAMJ8 ;
DR   A7H1R0, CLPP_CAMJD ;  P54413, CLPP_CAMJE ;  A1VXS0, CLPP_CAMJJ ;
DR   Q5HWX6, CLPP_CAMJR ;  B9KDZ6, CLPP_CAMLR ;  A4QKL7, CLPP_CAPBU ;
DR   Q3AF96, CLPP_CARHZ ;  Q05FR8, CLPP_CARRP ;  B8GX16, CLPP_CAUCN ;
DR   P0CAU1, CLPP_CAUCR ;  B0SZQ2, CLPP_CAUSK ;  Q8M9Y9, CLPP_CHAGL ;
DR   Q1ACH6, CLPP_CHAVU ;  Q19VC3, CLPP_CHLAT ;  Q3ATL3, CLPP_CHLCH ;
DR   P42379, CLPP_CHLMO ;  A1BI15, CLPP_CHLPD ;  P42380, CLPP_CHLRE ;
DR   A6MME7, CLPP_CHLSC ;  Q8KC73, CLPP_CHLTE ;  P56317, CLPP_CHLVU ;
DR   Q1QVW1, CLPP_CHRSD ;  Q7NUY9, CLPP_CHRVO ;  Q09MF2, CLPP_CITSI ;
DR   P58276, CLPP_CLOAB ;  A7FYI2, CLPP_CLOB1 ;  B2UX13, CLPP_CLOBA ;
DR   B2TPB9, CLPP_CLOBB ;  A5I6W1, CLPP_CLOBH ;  C1FLA6, CLPP_CLOBJ ;
DR   B1IND7, CLPP_CLOBK ;  A7GIH2, CLPP_CLOBL ;  B1L1D7, CLPP_CLOBM ;
DR   B8I8F5, CLPP_CLOCE ;  B9E685, CLPP_CLOK1 ;  A5N2K8, CLPP_CLOK5 ;
DR   A0Q2L1, CLPP_CLONN ;  Q0TQK2, CLPP_CLOP1 ;  Q8XKK1, CLPP_CLOPE ;
DR   Q0ST53, CLPP_CLOPS ;  Q891J7, CLPP_CLOTE ;  A3DJ10, CLPP_CLOTH ;
DR   A0A360, CLPP_COFAR ;  Q47XL8, CLPP_COLP3 ;  B6J8W4, CLPP_COXB1 ;
DR   B6J0W0, CLPP_COXB2 ;  A9KDS6, CLPP_COXBN ;  A9NDG0, CLPP_COXBR ;
DR   Q83DJ2, CLPP_COXBU ;  A4QKV6, CLPP_CRUWA ;  Q2QD64, CLPP_CUCSA ;
DR   Q0KBK4, CLPP_CUPNH ;  Q472D3, CLPP_CUPPJ ;  B3R4W1, CLPP_CUPTR ;
DR   A7M922, CLPP_CUSGR ;  A7M988, CLPP_CUSRE ;  Q93AD7, CLPP_CYAP8 ;
DR   A6H5K6, CLPP_CYCTA ;  Q0G9T7, CLPP_DAUCA ;  Q47FB6, CLPP_DECAR ;
DR   Q3Z8J8, CLPP_DEHE1 ;  A5FRE5, CLPP_DEHSB ;  Q3ZX82, CLPP_DEHSC ;
DR   Q1IWD9, CLPP_DEIGD ;  Q9RSZ7, CLPP_DEIRA ;  B8FA62, CLPP_DESAA ;
DR   C0QGT0, CLPP_DESAH ;  B8IYM2, CLPP_DESDA ;  Q30Z79, CLPP_DESDG ;
DR   C4XH03, CLPP_DESMR ;  A8ZXB7, CLPP_DESOH ;  Q6AK59, CLPP_DESPS ;
DR   A4J7L9, CLPP_DESRM ;  Q72CE8, CLPP_DESVH ;  B8DNL4, CLPP_DESVM ;
DR   A1VE85, CLPP_DESVV ;  A5EWF5, CLPP_DICNV ;  A8LJA8, CLPP_DINSH ;
DR   A6MMN2, CLPP_DIOEL ;  A4QL44, CLPP_DRANE ;  Q06GX2, CLPP_DRIGR ;
DR   A7ZIJ5, CLPP_ECO24 ;  P0A6G9, CLPP_ECO57 ;  A7ZX95, CLPP_ECOHS ;
DR   A1A8A6, CLPP_ECOK1 ;  Q0TKK4, CLPP_ECOL5 ;  P0A6G8, CLPP_ECOL6 ;
DR   B1J011, CLPP_ECOLC ;  P0A6G7, CLPP_ECOLI ;  Q1RF98, CLPP_ECOUT ;
DR   C5BCJ6, CLPP_EDWI9 ;  Q3YSQ3, CLPP_EHRCJ ;  Q2GFT8, CLPP_EHRCR ;
DR   Q5FFG7, CLPP_EHRRG ;  Q5HBX5, CLPP_EHRRW ;  B2KCS5, CLPP_ELUMP ;
DR   Q837R0, CLPP_ENTFA ;  P30063, CLPP_EPIVI ;  Q6D827, CLPP_ERWCT ;
DR   C4Z1T6, CLPP_EUBE2 ;  C4ZGF4, CLPP_EUBR3 ;  Q49KX3, CLPP_EUCGG ;
DR   B0TZA5, CLPP_FRAP2 ;  Q14IJ9, CLPP_FRAT1 ;  A7NBR6, CLPP_FRATF ;
DR   Q2A3U1, CLPP_FRATH ;  B2SG18, CLPP_FRATM ;  A0Q6S9, CLPP_FRATN ;
DR   Q0BM92, CLPP_FRATO ;  Q5NH47, CLPP_FRATT ;  A4IYB6, CLPP_FRATW ;
DR   Q8RHJ8, CLPP_FUSNN ;  B5EI27, CLPP_GEOBB ;  Q5KVD9, CLPP_GEOKA ;
DR   B3E1Z4, CLPP_GEOLS ;  Q39UH2, CLPP_GEOMG ;  B9M0Y1, CLPP_GEOSF ;
DR   Q74C82, CLPP_GEOSL ;  C6E2T0, CLPP_GEOSM ;  C5D7M9, CLPP_GEOSW ;
DR   A4ISQ2, CLPP_GEOTN ;  A5GFA0, CLPP_GEOUR ;  A0ZZ60, CLPP_GOSBA ;
DR   Q2L926, CLPP_GOSHI ;  Q7VP78, CLPP_HAEDU ;  Q4QMK5, CLPP_HAEI8 ;
DR   A5UE11, CLPP_HAEIE ;  A5UHJ6, CLPP_HAEIG ;  P43867, CLPP_HAEIN ;
DR   B8F822, CLPP_HAEPS ;  B0UW20, CLPP_HAES2 ;  Q2SK36, CLPP_HAHCH ;
DR   A1WUM7, CLPP_HALHL ;  B8CY74, CLPP_HALOH ;  C4K4P2, CLPP_HAMD5 ;
DR   Q17XD3, CLPP_HELAH ;  Q1KXT4, CLPP_HELAN ;  Q7VIN7, CLPP_HELHP ;
DR   B5Z7F6, CLPP_HELPG ;  Q1CT76, CLPP_HELPH ;  Q9ZL50, CLPP_HELPJ ;
DR   B2UT37, CLPP_HELPS ;  P56156, CLPP_HELPY ;  P48883, CLPP_HORVU ;
DR   Q16740, CLPP_HUMAN ;  Q5SD28, CLPP_HUPLU ;  Q5QXN8, CLPP_IDILO ;
DR   A6MMW9, CLPP_ILLOL ;  A6SY74, CLPP_JANMA ;  Q28NI7, CLPP_JANSC ;
DR   Q5FL55, CLPP_LACAC ;  Q03SM3, CLPP_LACBA ;  Q03AL0, CLPP_LACC3 ;
DR   B3WCR2, CLPP_LACCB ;  Q1GB31, CLPP_LACDA ;  Q04BH7, CLPP_LACDB ;
DR   B2GAL4, CLPP_LACF3 ;  Q042E8, CLPP_LACGA ;  A8YUD9, CLPP_LACH4 ;
DR   Q74K84, CLPP_LACJO ;  Q9CHQ3, CLPP_LACLA ;  Q9ZAB0, CLPP_LACLM ;
DR   Q030V9, CLPP_LACLS ;  Q88YH9, CLPP_LACPL ;  A5VII4, CLPP_LACRD ;
DR   B2G613, CLPP_LACRJ ;  Q1WTA8, CLPP_LACS1 ;  Q332V2, CLPP_LACSA ;
DR   Q38Y96, CLPP_LACSS ;  C1D539, CLPP_LARHH ;  Q1MQ79, CLPP_LAWIP ;
DR   Q5X451, CLPP_LEGPA ;  A5ID17, CLPP_LEGPC ;  Q5ZUD9, CLPP_LEGPH ;
DR   Q5WVJ0, CLPP_LEGPL ;  B1Y6H3, CLPP_LEPCP ;  Q8F352, CLPP_LEPIN ;
DR   A6YG63, CLPP_LEPTE ;  A4QLD1, CLPP_LEPVR ;  B1MXG9, CLPP_LEUCK ;
DR   Q0G9J4, CLPP_LIRTU ;  Q928C4, CLPP_LISIN ;  Q71WV9, CLPP_LISMF ;
DR   Q9RQI6, CLPP_LISMO ;  A4QLL9, CLPP_LOBMA ;  Q9BBQ9, CLPP_LOTJA ;
DR   B1HVR0, CLPP_LYSSC ;  B9EAG5, CLPP_MACCJ ;  Q2W3H9, CLPP_MAGSA ;
DR   A0LDT4, CLPP_MAGSM ;  P26567, CLPP_MAIZE ;  Q65RF6, CLPP_MANSM ;
DR   Q0AQ07, CLPP_MARMM ;  A6VW20, CLPP_MARMS ;  P12208, CLPP_MARPO ;
DR   Q9MUV8, CLPP_MESVI ;  B7KNT0, CLPP_METC4 ;  A9W5F5, CLPP_METEP ;
DR   Q1H1G0, CLPP_METFK ;  B8IN26, CLPP_METNO ;  B1Z9C7, CLPP_METPB ;
DR   A2SFB5, CLPP_METPP ;  B1LW28, CLPP_METRJ ;  Q2RL31, CLPP_MOOTA ;
DR   Q09WZ2, CLPP_MORIN ;  O88696, CLPP_MOUSE ;  Q09FT6, CLPP_NANDO ;
DR   A4QLV8, CLPP_NASOF ;  B2A158, CLPP_NATTJ ;  Q5F914, CLPP_NEIG1 ;
DR   A9LZN9, CLPP_NEIM0 ;  Q9JU33, CLPP_NEIMA ;  Q9JZ38, CLPP_NEIMB ;
DR   A1KUD9, CLPP_NEIMF ;  Q2GD19, CLPP_NEOSM ;  Q9TL09, CLPP_NEPOL ;
DR   Q3C1K4, CLPP_NICSY ;  Q33C07, CLPP_NICTO ;  Q0AJI2, CLPP_NITEC ;
DR   Q82Y57, CLPP_NITEU ;  Q1QL76, CLPP_NITHX ;  Q2Y6J0, CLPP_NITMU ;
DR   Q3JAJ8, CLPP_NITOC ;  A6Q1C1, CLPP_NITSB ;  Q3SRD2, CLPP_NITWN ;
DR   Q2G3T3, CLPP_NOVAD ;  A1XFY0, CLPP_NUPAD ;  Q6EW27, CLPP_NYMAL ;
DR   Q8ENM5, CLPP_OCEIH ;  Q9MTJ8, CLPP_OENEH ;  B6JGU7, CLPP_OLICO ;
DR   A4QJV6, CLPP_OLIPU ;  Q20F17, CLPP_OLTVI ;  Q6ENE9, CLPP_ORYNI ;
DR   P0C312, CLPP_ORYSA ;  P0C313, CLPP_ORYSI ;  P0C314, CLPP_ORYSJ ;
DR   Q0P3P4, CLPP_OSTTA ;  Q68RY2, CLPP_PANGI ;  P54414, CLPP_PARDE ;
DR   Q9CJM2, CLPP_PASMU ;  Q03GX1, CLPP_PEDPA ;  Q3A3X5, CLPP_PELCD ;
DR   Q06FP3, CLPP_PELHO ;  Q3B5V8, CLPP_PELLD ;  A1AN85, CLPP_PELPD ;
DR   A5D447, CLPP_PELTS ;  Q4FM94, CLPP_PELUB ;  Q3BAL3, CLPP_PHAAO ;
DR   A4GGD0, CLPP_PHAVU ;  Q7N0L3, CLPP_PHOLL ;  Q6LNW0, CLPP_PHOPR ;
DR   Q6YXM7, CLPP_PHYPA ;  P36387, CLPP_PINCO ;  Q85X43, CLPP_PINKO ;
DR   P84723, CLPP_PINST ;  P41609, CLPP_PINTH ;  Q06GN5, CLPP_PIPCE ;
DR   Q09G21, CLPP_PLAOC ;  Q14FD2, CLPP_POPAL ;  A4GYT6, CLPP_POPTR ;
DR   Q7MX09, CLPP_PORGI ;  B4EU53, CLPP_PROMH ;  A4SDA4, CLPP_PROVI ;
DR   Q48KZ0, CLPP_PSE14 ;  Q15R46, CLPP_PSEA6 ;  Q3ZJ12, CLPP_PSEAK ;
DR   Q1ICA8, CLPP_PSEE4 ;  Q4K9J6, CLPP_PSEF5 ;  C3JYK0, CLPP_PSEFS ;
DR   Q3IF46, CLPP_PSEHT ;  A4XTZ5, CLPP_PSEMY ;  A5W635, CLPP_PSEP1 ;
DR   Q3K9W9, CLPP_PSEPF ;  B0KJG6, CLPP_PSEPG ;  Q88KJ0, CLPP_PSEPK ;
DR   B1J692, CLPP_PSEPW ;  Q87YR6, CLPP_PSESM ;  Q4ZVM7, CLPP_PSEU2 ;
DR   Q8WHZ7, CLPP_PSINU ;  Q4FQB9, CLPP_PSYA2 ;  Q1Q8J2, CLPP_PSYCK ;
DR   A1SUW7, CLPP_PSYIN ;  Q1LM62, CLPP_RALME ;  Q8XYP7, CLPP_RALSO ;
DR   A1XGR3, CLPP_RANMC ;  Q21Y67, CLPP_RHOFD ;  Q2IWZ4, CLPP_RHOP2 ;
DR   Q07NN6, CLPP_RHOP5 ;  Q6N5L3, CLPP_RHOPA ;  Q215J2, CLPP_RHOPB ;
DR   Q135W7, CLPP_RHOPS ;  B3Q7P5, CLPP_RHOPT ;  Q2RU45, CLPP_RHORT ;
DR   A3PKS1, CLPP_RHOS1 ;  Q3J1G6, CLPP_RHOS4 ;  A4WSH8, CLPP_RHOS5 ;
DR   B9KJU9, CLPP_RHOSK ;  A8GNZ4, CLPP_RICAH ;  Q1RJH2, CLPP_RICBR ;
DR   A8EYM5, CLPP_RICCK ;  Q92HM5, CLPP_RICCN ;  Q4ULF0, CLPP_RICFE ;
DR   Q9ZD29, CLPP_RICPR ;  C4K1D4, CLPP_RICPU ;  A8GSH5, CLPP_RICRS ;
DR   Q68WL5, CLPP_RICTY ;  Q165F9, CLPP_ROSDO ;  Q1AVS9, CLPP_RUBXD ;
DR   A1AVN6, CLPP_RUTMC ;  Q21KA9, CLPP_SACD2 ;  Q6L377, CLPP_SACHY ;
DR   Q6ENT9, CLPP_SACOF ;  Q57SB5, CLPP_SALCH ;  B5QTJ6, CLPP_SALEP ;
DR   B4T9E3, CLPP_SALHS ;  B4SWU1, CLPP_SALNS ;  Q5PFN4, CLPP_SALPA ;
DR   B5BD83, CLPP_SALPK ;  B4TMC6, CLPP_SALSV ;  P0A1D8, CLPP_SALTI ;
DR   P0A1D7, CLPP_SALTY ;  A1S4X5, CLPP_SHEAM ;  B8E5E9, CLPP_SHEB2 ;
DR   A3D305, CLPP_SHEB5 ;  A6WLQ1, CLPP_SHEB8 ;  A9KWH7, CLPP_SHEB9 ;
DR   Q12LA1, CLPP_SHEDO ;  Q07ZX8, CLPP_SHEFN ;  B0TLU9, CLPP_SHEHH ;
DR   A3QFX6, CLPP_SHELP ;  Q8EG19, CLPP_SHEON ;  A8H614, CLPP_SHEPA ;
DR   A4Y5I2, CLPP_SHEPC ;  B8CRF7, CLPP_SHEPW ;  A0KYL9, CLPP_SHESA ;
DR   A8FTH9, CLPP_SHESH ;  Q0HHA1, CLPP_SHESM ;  Q0HTK7, CLPP_SHESR ;
DR   A1RL89, CLPP_SHESW ;  B1KLT7, CLPP_SHEWM ;  Q325G4, CLPP_SHIBS ;
DR   Q32JJ3, CLPP_SHIDS ;  Q0T7E6, CLPP_SHIF8 ;  P0A6H0, CLPP_SHIFL ;
DR   Q3Z4W6, CLPP_SHISS ;  Q5LUQ0, CLPP_SILPO ;  Q1GGF6, CLPP_SILST ;
DR   Q2NV79, CLPP_SODGM ;  Q2MIG3, CLPP_SOLBU ;  Q2MI76, CLPP_SOLLC ;
DR   Q27S24, CLPP_SOLTU ;  A1E9U9, CLPP_SORBI ;  Q2PMR0, CLPP_SOYBN ;
DR   Q1GPH5, CLPP_SPHAL ;  Q9M3K5, CLPP_SPIOL ;  A7WZR9, CLPP_STAA1 ;
DR   A6TZP7, CLPP_STAA2 ;  Q2FIM5, CLPP_STAA3 ;  Q2G036, CLPP_STAA8 ;
DR   A5IQX2, CLPP_STAA9 ;  Q2YSF8, CLPP_STAAB ;  Q5HHQ0, CLPP_STAAC ;
DR   A6QF76, CLPP_STAAE ;  P63785, CLPP_STAAM ;  P99089, CLPP_STAAN ;
DR   Q6GIM3, CLPP_STAAR ;  Q6GB62, CLPP_STAAS ;  A8Z045, CLPP_STAAT ;
DR   P63786, CLPP_STAAW ;  B9DJL4, CLPP_STACT ;  Q5HQW0, CLPP_STAEQ ;
DR   Q8CTE0, CLPP_STAES ;  Q4L4J5, CLPP_STAHJ ;  Q32RU0, CLPP_STAPU ;
DR   Q49VZ2, CLPP_STAS1 ;  Q3JZV0, CLPP_STRA1 ;  Q8E3X0, CLPP_STRA3 ;
DR   Q8DYA5, CLPP_STRA5 ;  C0M7M8, CLPP_STRE4 ;  A8AYP9, CLPP_STRGC ;
DR   B2FQR2, CLPP_STRMK ;  Q8DST7, CLPP_STRMU ;  P69884, CLPP_STRP1 ;
DR   Q04LF4, CLPP_STRP2 ;  P0DA34, CLPP_STRP3 ;  Q5XDM4, CLPP_STRP6 ;
DR   C1C691, CLPP_STRP7 ;  P69886, CLPP_STRP8 ;  Q1JDA9, CLPP_STRPB ;
DR   Q1JN83, CLPP_STRPC ;  Q1JID4, CLPP_STRPD ;  Q1J887, CLPP_STRPF ;
DR   A2RG72, CLPP_STRPG ;  B1IAS4, CLPP_STRPI ;  B8ZN39, CLPP_STRPJ ;
DR   Q48V25, CLPP_STRPM ;  P63787, CLPP_STRPN ;  P0DA35, CLPP_STRPQ ;
DR   B2INC9, CLPP_STRPS ;  B5XJZ8, CLPP_STRPZ ;  P63788, CLPP_STRR6 ;
DR   A4W2X9, CLPP_STRS2 ;  C0MGT5, CLPP_STRS7 ;  P36398, CLPP_STRSL ;
DR   A3CPK8, CLPP_STRSV ;  Q5M1A8, CLPP_STRT1 ;  Q5M5U4, CLPP_STRT2 ;
DR   Q03M78, CLPP_STRTD ;  B9DTU8, CLPP_STRU0 ;  C1CD96, CLPP_STRZJ ;
DR   C1CJJ5, CLPP_STRZP ;  C1CQK8, CLPP_STRZT ;  Q30NX1, CLPP_SULDN ;
DR   A6Q675, CLPP_SULNB ;  Q2LTK5, CLPP_SYNAS ;  A0LEF1, CLPP_SYNFM ;
DR   Q0AWF0, CLPP_SYNWW ;  C5BTJ0, CLPP_TERTT ;  A8F754, CLPP_THELT ;
DR   Q9WZF9, CLPP_THEMA ;  A5IJ91, CLPP_THEP1 ;  B0KBA4, CLPP_THEP3 ;
DR   B0K533, CLPP_THEPX ;  B1L812, CLPP_THESQ ;  Q72L15, CLPP_THET2 ;
DR   Q5SKM8, CLPP_THET8 ;  Q8RC25, CLPP_THETN ;  B5YI38, CLPP_THEYD ;
DR   Q31GF1, CLPP_THICR ;  Q3SI98, CLPP_THIDA ;  P12210, CLPP_TOBAC ;
DR   C5CJT4, CLPP_VARPS ;  A1WR17, CLPP_VEREI ;  A5CXJ8, CLPP_VESOH ;
DR   A5F6X0, CLPP_VIBC3 ;  Q9KQS6, CLPP_VIBCH ;  C3LNM6, CLPP_VIBCM ;
DR   Q5E6Q5, CLPP_VIBF1 ;  B5FBZ8, CLPP_VIBFM ;  A7MV87, CLPP_VIBHB ;
DR   Q87R80, CLPP_VIBPA ;  B7VI00, CLPP_VIBSL ;  Q8DG26, CLPP_VIBVU ;
DR   Q7MMG7, CLPP_VIBVY ;  Q0ZIZ4, CLPP_VITVI ;  P24064, CLPP_WHEAT ;
DR   Q8D346, CLPP_WIGBR ;  Q73I59, CLPP_WOLPM ;  B3CLB1, CLPP_WOLPP ;
DR   Q7M7M3, CLPP_WOLSU ;  Q5GS83, CLPP_WOLTR ;  C0R2W3, CLPP_WOLWR ;
DR   Q8PNI5, CLPP_XANAC ;  Q3BWQ1, CLPP_XANC5 ;  Q4URL4, CLPP_XANC8 ;
DR   B0RTF7, CLPP_XANCB ;  Q8PBY6, CLPP_XANCP ;  Q2P6Z0, CLPP_XANOM ;
DR   B2SMI3, CLPP_XANOP ;  Q5H434, CLPP_XANOR ;  A7ILC6, CLPP_XANP2 ;
DR   B2I8K3, CLPP_XYLF2 ;  Q9PE41, CLPP_XYLFA ;  B0U5N1, CLPP_XYLFM ;
DR   Q87E51, CLPP_XYLFT ;  A1JNN2, CLPP_YERE8 ;  Q60107, CLPP_YEREN ;
DR   A7FLC4, CLPP_YERP3 ;  Q1C4K8, CLPP_YERPA ;  Q8ZC65, CLPP_YERPE ;
DR   Q1CL65, CLPP_YERPN ;  A4TPE3, CLPP_YERPP ;  Q66DT4, CLPP_YERPS ;
DR   Q32RQ7, CLPP_ZYGCR ;  Q5NNY8, CLPP_ZYMMO ;
//
ID   3.4.21.93
DE   Proprotein convertase 1.
AN   NEC 1.
AN   Neuroendocrine convertase 1.
AN   PC1.
AN   Prohormone convertase I.
CA   Release of protein hormones, neuropeptides and renin from their
CA   precursors, generally by hydrolysis of -Lys-Arg-|- bonds.
CC   -!- A calcium dependent enzyme, maximally active at about pH 5.5.
CC   -!- Substrates include pro-opiomelanocortin, prorenin, proenkephalin,
CC       prodynorphin, prosomatostatin and proinsulin.
CC   -!- Unlike prohormone convertase 2, does not cleave proluteinizing-
CC       hormone-releasing hormone.
CC   -!- Usually processing of prodynorphin occurs at a bond in which P2 is
CC       Thr.
CC   -!- Present in the regulated secretory pathway of neuroendocrine cells,
CC       commonly actin co-operatively with prohormone convertase 2.
CC   -!- Belongs to peptidase family S8.
PR   PROSITE; PDOC00125;
DR   Q9GLR1, NEC1_BOVIN ;  P29120, NEC1_HUMAN ;  P63239, NEC1_MOUSE ;
DR   P63240, NEC1_MUSCO ;  P28840, NEC1_RAT   ;
//
ID   3.4.21.94
DE   Proprotein convertase 2.
AN   NEC 2.
AN   Neuroendocrine convertase 2.
AN   PC(2).
AN   Prohormone convertase II.
CA   Release of protein hormones and neuropeptides from their precursors,
CA   generally by hydrolysis of -Lys-Arg-|- bonds.
CC   -!- A calcium dependent enzyme, maximally active at about pH 5.5.
CC   -!- Specificity is broader than that of prohormone convertase 1.
CC   -!- Substrates include pro-opiomelanocortin, proenkephalin, prodynorphin,
CC       proinsulin and proluteinizing-hormone-releasing hormone.
CC   -!- Unlike prohormone convertase 1, does not cleave prorenin or
CC       prosomatostatin.
CC   -!- Usually processing of prodynorphin occurs at a bond in which P2 is
CC       Thr.
CC   -!- Present in the regulated secretory pathway of neuroendocrine cells,
CC       commonly actin co-operatively with prohormone convertase 1.
CC   -!- Belongs to peptidase family S8.
PR   PROSITE; PDOC00125;
DR   Q9GLR0, NEC2_BOVIN ;  P16519, NEC2_HUMAN ;  P21661, NEC2_MOUSE ;
DR   Q03333, NEC2_PIG   ;  Q5REC2, NEC2_PONAB ;  P28841, NEC2_RAT   ;
//
ID   3.4.21.95
DE   Snake venom factor V activator.
AN   Factor V-activating proteinase.
AN   RVV-V component.
CA   Fully activates human clotting factor V by a single cleavage at the 1545-
CA   Trp-Tyr-Leu-Arg-|-Ser-Asn-Asn-Gly-1552 bond. Cattle, but not rabbit,
CA   factor V is cleaved, and no other proteins of the clotting system are
CA   attacked. Esterase activity is observed on Bz-Arg-OEt and Tos-Arg-OMe,
CA   and amidase activity on Phe-pipecolyl-Arg-NHPhNO(2).
CC   -!- Inhibited by diisopropyl fluorophosphate.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   P18964, VSPA_DABRU ;  P18965, VSPG_DABRU ;
//
ID   3.4.21.96
DE   Lactocepin.
AN   Extracellular lactococcal proteinase.
AN   Lactococcal cell envelope-associated proteinase.
AN   Wall-associated serine proteinase.
CA   Endopeptidase activity with very broad specificity, although some subsite
CA   preference have been noted, e.g. large hydrophobic residues in the P1 and
CA   P4 positions, and Pro in the P2 position. Best known for its action on
CA   caseins, although it has been shown to hydrolyze hemoglobin and oxidized
CA   insulin B-chain.
CC   -!- Responsible for the hydrolysis of casein in milk and the provision of
CC       peptides essential for cell growth.
CC   -!- Specificity differences between lactocepins from different starter
CC       strains may be partly responsible for imparating different flavor
CC       qualities to cheese.
CC   -!- Belongs to peptidase family S8.
PR   PROSITE; PDOC00125;
DR   P15293, P2P_LACLC  ;  Q02470, P2P_LACPA  ;  P15292, P3P_LACLS  ;
//
ID   3.4.21.97
DE   Assemblin.
CA   Cleaves -Ala-|-Ser- and -Ala-|-Ala- bonds in the scaffold protein.
CC   -!- Involved in the breakdown of the scaffold protein during the late
CC       stages of assembly of the herpes-virus virion.
CC   -!- Inhibited by diisopropyl fluorophosphate.
CC   -!- Belongs to peptidase family S21.
DR   P54817, PPR_BHV1C  ;  Q1HVC7, PPR_EBVA8  ;  P03234, PPR_EBVB9  ;
DR   Q3KSP9, PPR_EBVG   ;  P28936, PPR_EHV1B  ;  P84454, PPR_EHV1V  ;
DR   P52369, PPR_EHV2   ;  Q18LE3, PPR_ELHVK  ;  Q9E6P2, PPR_GAHVM  ;
DR   P16753, PPR_HCMVA  ;  P10210, PPR_HHV11  ;  P89449, PPR_HHV2H  ;
DR   P24433, PPR_HHV6U  ;  P52351, PPR_HHV7J  ;  P23984, PPR_ILTVT  ;
DR   Q6UDK6, PPR_PSHV1  ;  P16046, PPR_SCMVC  ;  Q01002, PPR_SHV21  ;
DR   P09286, PPR_VZVD   ;  O36367, PRR_ALHV1  ;  Q9QJ30, PRR_HHV6Z  ;
//
ID   3.4.21.98
DE   Hepacivirin.
AN   Cpro-2.
AN   Hepatitis C virus NS3 serine proteinase.
CA   Hydrolysis of four peptide bonds in the viral precursor polyprotein,
CA   commonly with Asp or Glu in the P6 position, Cys or Thr in P1 and Ser or
CA   Ala in P1'.
CC   -!- Encoded by the genome of the viruses of the hepatitis C group,
CC       and contributes to the maturation of the precursor polyproteins.
CC   -!- The enzyme is greatly activated by binding of the 54-residue NS4A
CC       'cofactor' protein also derived from the viral polyprotein.
CC   -!- Belongs to peptidase family S29.
DR   Q69422, POLG_GBVB  ;  P26664, POLG_HCV1  ;  Q5I2N3, POLG_HCV6A ;
DR   Q68749, POLG_HCVBB ;  P26663, POLG_HCVBK ;  Q9WMX2, POLG_HCVCO ;
DR   O39929, POLG_HCVED ;  O39927, POLG_HCVEU ;  O39928, POLG_HCVEV ;
DR   P27958, POLG_HCVH  ;  Q81754, POLG_HCVH9 ;  Q913D4, POLG_HCVIN ;
DR   Q03463, POLG_HCVJ1 ;  O92972, POLG_HCVJ4 ;  P26660, POLG_HCVJ6 ;
DR   P26661, POLG_HCVJ8 ;  P26662, POLG_HCVJA ;  Q99IB8, POLG_HCVJF ;
DR   Q68801, POLG_HCVJK ;  Q68798, POLG_HCVJL ;  Q9DHD6, POLG_HCVJP ;
DR   Q00269, POLG_HCVJT ;  Q81495, POLG_HCVK3 ;  Q81258, POLG_HCVNZ ;
DR   Q913V3, POLG_HCVR6 ;  O91936, POLG_HCVSA ;  O92529, POLG_HCVT5 ;
DR   Q81487, POLG_HCVTR ;  P29846, POLG_HCVTW ;  Q9QAX1, POLG_HCVVA ;
DR   O92530, POLG_HCVVN ;  O92531, POLG_HCVVO ;  O92532, POLG_HCVVP ;
//
ID   3.4.21.99
DE   Spermosin.
CA   Hydrolyzes arginyl bonds, preferably with Pro in the P2 position.
CC   -!- The enzyme from the ascidian (Prochordate) Halocynthia roretzi is
CC       localized in the sperm head, and released during sperm activation.
CC   -!- A proline-rich region is involved in binding to the vitelline coat of
CC       the egg.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   Q966V2, SPRM_HALRO ;
//
ID   3.4.21.100
DE   Sedolisin.
AN   Pseudomonalisin.
AN   Pseudomonapepsin.
AN   Pseudomonas sp. pepstatin-insensitive carboxyl proteinase.
AN   Sedolysin.
CA   Hydrolysis of the B chain of insulin at 13-Glu-|-Ala-14, 15-Leu-|-Tyr-16
CA   and 25-Phe-|-Tyr-26 and angiotensin I at 4-Tyr-|-Ile-5. A good synthetic
CA   substrate is Lys-Pro-Ile-Glu-Phe-|-Phe(NO(2))-Arg-Leu.
CC   -!- An enzyme secreted by Pseudomonas sp. No. 101.
CC   -!- Optimum pH 4.
CC   -!- It is distinguished from EC 3.4.21.101 by its insensitivity to EPNP
CC       and from EC 3.4.23.31 by this property and by its unrelated amino-
CC       acid sequence.
CC   -!- Inhibited by tyrostatin, a peptide aldehyde.
CC   -!- Belongs to peptidase family S53.
CC   -!- Formerly EC 3.4.23.37.
DR   P42790, PICP_PSESR ;
//
ID   3.4.21.101
DE   Xanthomonalisin.
AN   Sedolisin-B.
AN   Xanthomonapepsin.
AN   Xanthomonas aspartic proteinase.
CA   Cleavage of casein.
CC   -!- Secreted by the bacterium Xanthomonas sp.
CC   -!- Belongs to peptidase family S53.
CC   -!- Formerly EC 3.4.23.33.
DR   Q60106, XANP_XANS2 ;
//
ID   3.4.21.102
DE   C-terminal processing peptidase.
AN   Photosystem II D1 protein processing peptidase.
AN   Protease Re.
AN   Tail-specific protease.
AN   Tsp protease.
CA   The enzyme shows specific recognition of a C-terminal tripeptide, Xaa-
CA   Yaa-Zaa, in which Xaa is preferably Ala or Leu, Yaa is preferably Ala or
CA   Tyr, and Zaa is preferably Ala, but then cleaves at a variable distance
CA   from the C-terminus. A typical cleavage is -Ala-Ala-|-Arg-Ala-Ala-
CA   Lys-Glu-Asn-Tyr-Ala-Leu-Ala-Ala.
CC   -!- In the plant chloroplast, the enzyme removes the C-terminal extension
CC       of the D1 polypeptide of photosystem II; this proteolytic processing
CC       is necessary to allow the light-driven assembly of the tetranuclear
CC       manganese cluster, which is responsible for photosynthetic water
CC       oxidation.
CC   -!- Belongs to peptidase family S41.
DR   O34666, CTPA_BACSU ;  Q44879, CTPA_BARBK ;  P42784, CTPA_SYNP2 ;
DR   Q55669, CTPA_SYNY3 ;  O35002, CTPB_BACSU ;  P23865, PRC_ECOLI  ;
DR   P45306, PRC_HAEIN  ;  P43669, PRC_SALTY  ;
//
ID   3.4.21.103
DE   Physarolisin.
AN   Dictyostelium discoideum aspartic proteinase.
AN   Dictyostelium discoideum aspartic proteinase E.
AN   Physaropepsin.
AN   Physarum aspartic proteinase.
AN   Physarum flavicomum aspartic proteinase.
AN   Physarum polycephalum acid proteinase.
CA   Milk clotting activity. Preferential cleavage of 8-Gly-|-Ser-9 in B chain
CA   of insulin most rapidly, followed by 11-Leu-|-Val-12,
CA   19-Cys(SO(3)H)-|-Gly and 24-Phe-|-Phe-25. No action on Ac-Phe-Tyr(I)(2).
CC   -!- From the slime mold Physarum polycephalum.
CC   -!- Is not inhibited by pepstatin, but is blocked by methyl
CC       2-diazoacetamidohexanoate.
CC   -!- Closely similar enzymes are found in Dictyostelium discoideum and
CC       P.flavicomum.
CC   -!- Belongs to peptidase family S53.
CC   -!- Formerly EC 3.4.4.17, EC 3.4.23.6 and EC 3.4.23.27.
DR   Q8MZS4, PHYSA_PHYPO;
//
ID   3.4.21.104
DE   Mannan-binding lectin-associated serine protease-2.
AN   Mannan-binding lectin-associated serine peptidase 2.
AN   Mannose-binding lectin-associated serine protease-2.
AN   MASP-2.
AN   MASP2.
AN   MBP-associated serine protease-2.
CA   Selective cleavage after Arg-223 in complement component C2 (-Ser-
CA   Leu-Gly-Arg-|-Lys-Ile-Gln-Ile) and after Arg-76 in complement component
CA   C4 (-Gly-Leu-Gln-Arg-|-Ala-Leu-Glu-Ile).
CC   -!- Mannan-binding lectin (MBL) recognizes patterns of neutral
CC       carbohydrates, such as mannose and N-acetylglucosamine, on a wide
CC       range of microbial surfaces and is able to initiate activation of the
CC       lectin pathway of complement.
CC   -!- Displays C1s-like esterolytic activity (cf. EC 3.4.21.42).
CC   -!- It also cleaves C4 and C2 with efficiencies that are relatively
CC       higher than those of EC 3.4.21.42.
CC   -!- Belongs to peptidase family S1A.
PR   PROSITE; PDOC00124;
DR   O00187, MASP2_HUMAN;  Q91WP0, MASP2_MOUSE;  Q9JJS8, MASP2_RAT  ;
//
ID   3.4.21.105
DE   Rhomboid protease.
CA   Cleaves type-1 transmembrane domains using a catalytic dyad composed of
CA   serine and histidine that are contributed by different transmembrane
CA   domains.
CC   -!- These endopeptidases are multi-spanning membrane proteins.
CC   -!- Their catalytic site is embedded within the membrane and they cleave
CC       type-1 transmembrane domains.
CC   -!- Important for embryo development in Drosophila melanogaster.
CC   -!- Rhomboid is a key regulator of EGF receptor signaling and is
CC       responsible for cleaving Spitz, the main ligand of the Drosophila EGF
CC       receptor pathway.
CC   -!- Parasite-encoded rhomboid enzymes are also important for invasion of
CC       host cells by Toxoplasma and the malaria parasite.
CC   -!- Belongs to peptidase family S54.
DR   P46116, AARA_PROST ;  A8AQX4, GLPG_CITK8 ;  A7ZSV4, GLPG_ECO24 ;
DR   B7UKC8, GLPG_ECO27 ;  B7MDQ0, GLPG_ECO45 ;  B7L4V0, GLPG_ECO55 ;
DR   Q8X6Z6, GLPG_ECO57 ;  B5YTX6, GLPG_ECO5E ;  B7NMI8, GLPG_ECO7I ;
DR   B7N156, GLPG_ECO81 ;  B7M2I4, GLPG_ECO8A ;  C4ZVX5, GLPG_ECOBW ;
DR   B1X769, GLPG_ECODH ;  A8A5N2, GLPG_ECOHS ;  A1AGU7, GLPG_ECOK1 ;
DR   Q0TC44, GLPG_ECOL5 ;  Q8FCS5, GLPG_ECOL6 ;  B1IP42, GLPG_ECOLC ;
DR   P09391, GLPG_ECOLI ;  B7NE28, GLPG_ECOLU ;  B6I2Y7, GLPG_ECOSE ;
DR   B1LI84, GLPG_ECOSM ;  Q1R5L1, GLPG_ECOUT ;  A4WFK8, GLPG_ENT38 ;
DR   Q6CZL3, GLPG_ERWCT ;  B7LSC6, GLPG_ESCF3 ;  P44783, GLPG_HAEIN ;
DR   B5XTR5, GLPG_KLEP3 ;  A6TF43, GLPG_KLEP7 ;  Q7N9W4, GLPG_PHOLL ;
DR   B5F8P0, GLPG_SALA4 ;  A9MMA7, GLPG_SALAR ;  Q57IV1, GLPG_SALCH ;
DR   B5FKE3, GLPG_SALDC ;  B5R383, GLPG_SALEP ;  B5R7J1, GLPG_SALG2 ;
DR   B4TKV0, GLPG_SALHS ;  B4SVM1, GLPG_SALNS ;  Q5PLZ8, GLPG_SALPA ;
DR   B5BHH5, GLPG_SALPK ;  B4TY77, GLPG_SALSV ;  Q8Z229, GLPG_SALTI ;
DR   Q8ZLH5, GLPG_SALTY ;  A8GKU2, GLPG_SERP5 ;  B2U3N2, GLPG_SHIB3 ;
DR   Q31VK9, GLPG_SHIBS ;  Q32AN6, GLPG_SHIDS ;  Q0SZP2, GLPG_SHIF8 ;
DR   Q83PV6, GLPG_SHIFL ;  Q3YWA4, GLPG_SHISS ;  Q2NQH3, GLPG_SODGM ;
DR   A1JSF0, GLPG_YERE8 ;  A7FNW6, GLPG_YERP3 ;  Q1C2L2, GLPG_YERPA ;
DR   B2K5W4, GLPG_YERPB ;  Q7CFX8, GLPG_YERPE ;  Q1CCK6, GLPG_YERPN ;
DR   A4TGR2, GLPG_YERPP ;  Q664J1, GLPG_YERPS ;  B1JHY8, GLPG_YERPY ;
DR   P54493, GLUP_BACSU ;  Q2KHV4, PARL_BOVIN ;  Q58EK4, PARL_DANRE ;
DR   Q9H300, PARL_HUMAN ;  Q5XJY4, PARL_MOUSE ;  Q5R5H4, PARL_PONAB ;
DR   Q3B8P0, PARL_RAT   ;  P53259, PCP1_YEAST ;  O75783, RHBL1_HUMAN;
DR   Q8VC82, RHBL1_MOUSE;  O88779, RHBL1_RAT  ;  Q695U0, RHBL1_TOXGO;
DR   Q9NX52, RHBL2_HUMAN;  A2AGA4, RHBL2_MOUSE;  Q695T9, RHBL2_TOXGO;
DR   P58872, RHBL3_HUMAN;  P58873, RHBL3_MOUSE;  Q6IUY1, RHBL3_TOXGO;
DR   Q695T8, RHBL4_TOXGO;  Q6GV23, RHBL5_TOXGO;  Q2PP52, RHBL6_TOXGO;
DR   P20350, RHOM_DROME ;  Q19821, ROM1_CAEEL ;  P34356, ROM2_CAEEL ;
//
ID   3.4.21.106
DE   Hepsin.
CA   Cleavage after basic amino-acid residues, with Arg strongly preferred to
CA   Lys.
CC   -!- This type-II membrane-associated serine peptidase has been implicated
CC       in cell growth and development.
CC   -!- The enzyme has been shown to activate blood coagulation factor VII by
CC       cleavage of the 152-Arg-|-Ile-153 peptide bound in BHK cells, thus
CC       indicating a possible role in the initiation of blood coagulation.
CC   -!- There is no cleavage after aromatic or aliphatic residues.
CC   -!- The occupancy of the S2 site is an absolute requirement for catalysis
CC       and a basic residue at that site is preferred to an aliphatic
CC       residue.
CC   -!- The nature of the residue at S3 also affects hydrolysis, with Gln
CC       being much more favorable than Ala.
CC   -!- Belongs to peptidase family S1A.
PR   PROSITE; PDOC00124;
DR   P05981, HEPS_HUMAN ;  O35453, HEPS_MOUSE ;  Q5R5E8, HEPS_PONAB ;
DR   Q05511, HEPS_RAT   ;
//
ID   3.4.21.107
DE   Peptidase Do.
AN   High temperature requirement protease A.
AN   HrtA heat shock protein.
AN   Protease Do.
CA   Acts on substrates that are at least partially unfolded. The cleavage
CA   site P1 residue is normally between a pair of hydrophobic residues, such
CA   as Val-|-Val.
CC   -!- This serine endopeptidase is essential for the clearance of denatured
CC       or aggregated proteins from the inner-membrane and periplasmic space
CC       in Escherichia coli.
CC   -!- Natural substrates of the enzyme include colicin A lysis protein,
CC       pilin subunits and MalS from E.coli.
CC   -!- The enzyme has weak peptidase activity with casein and other non-
CC       native substrates.
CC   -!- The peptidase acts as a chaperone at low temperatures but switches to
CC       a peptidase (heat shock protein) at higher temperatures.
CC   -!- Molecular chaperones and peptidases control the folded state of
CC       proteins by recognizing hydrophobic stretches of polypeptide that
CC       become exposed by misfolding or unfolding.
CC   -!- They then bind these hydrophobic substrates to prevent aggregation or
CC       assist in protein refolding.
CC   -!- If attempts at refolding fail, then irreversibly damaged proteins are
CC       degraded by peptidases such as this enzyme.
CC   -!- Belongs to peptidase family S1B.
//
ID   3.4.21.108
DE   HtrA2 peptidase.
AN   High temperature requirement protein A2.
AN   HtrA2 protease.
AN   Omi stress-regulated endoprotease.
AN   Serine proteinase OMI.
CA   Cleavage of non-polar aliphatic amino-acids at the P1 position, with a
CA   preference for Val, Ile and Met. At the P2 and P3 positions, Arg is
CA   selected most strongly with a secondary preference for other hydrophilic
CA   residues.
CC   -!- Up-regulated in mammalian cells in response to stress induced by both
CC       heat shock and tunicamycin treatment.
CC   -!- Can induce apoptosis in a caspase-independent manner through its
CC       peptidase activity and in a caspase-dependent manner by disrupting
CC       the interaction between caspase and the inhibitor of apoptosis (IAP).
CC   -!- Belongs to peptidase family S1B.
DR   A0JNK3, HTRA2_BOVIN;  B3LVG7, HTRA2_DROAN;  B3P3J9, HTRA2_DROER;
DR   B4JTT7, HTRA2_DROGR;  Q9VFJ3, HTRA2_DROME;  B4K835, HTRA2_DROMO;
DR   B4G316, HTRA2_DROPE;  Q297U2, HTRA2_DROPS;  B4HEM8, HTRA2_DROSE;
DR   B4QZU6, HTRA2_DROSI;  B4LY58, HTRA2_DROVI;  B4N937, HTRA2_DROWI;
DR   B4PST0, HTRA2_DROYA;  O43464, HTRA2_HUMAN;  Q9JIY5, HTRA2_MOUSE;
//
ID   3.4.21.109
DE   Matriptase.
AN   Epithin.
AN   Membrane-type serine protease 1.
AN   MT-SP1.
AN   Prostamin.
AN   Serine endopeptidase SNC19.
AN   Serine protease 14.
AN   Serine protease TADG-15.
AN   Tumor-associated differentially-expressed gene 15 protein.
CA   Cleaves various synthetic substrates with Arg or Lys at the P1 position
CA   and prefers small side-chain amino acids, such as Ala and Gly, at the P2
CA   position.
CC   -!- This trypsin-like integral-membrane serine peptidase has been
CC       implicated in breast cancer invasion and metastasis.
CC   -!- Can activate hepatocyte growth factor/scattering factor (HGF/SF) by
CC       cleavage of the two-chain form at an Arg residue to give active
CC       alpha- and beta-HGF, but it does not activate plasminogen, which
CC       shares high homology with HGF.
CC   -!- Can also activate urokinase plasminogen activator (uPA), which
CC       initiates the matrix-degrading peptidase cascade.
CC   -!- Belongs to peptidase family S1A.
PR   PROSITE; PDOC00124;
DR   Q0IIH7, ST14_BOVIN ;  Q9Y5Y6, ST14_HUMAN ;  P56677, ST14_MOUSE ;
//
ID   3.4.21.110
DE   C5a peptidase.
AN   SCP.
AN   Streptococcal C5a peptidase.
CA   The primary cleavage site is at 67-His-|-Lys-68 in human C5a with a minor
CA   secondary cleavage site at 58-Ala-|-Ser-59.
CC   -!- Surface-associated subtilisin-like serine peptidase with very
CC       specific substrate specificity.
CC   -!- Virulent strains of streptococci, including Streptococcus pyogenes,
CC       can evade human detection and phagocytosis by destroying the
CC       complement chemotaxin C5a.
CC   -!- Cleavage of human C5a by this enzyme reduces the ability of C5a to
CC       bind receptors on the surface of polymorphonuclear neutrophil
CC       leukocytes (PMNLs) and thereby abolishes its chemotactic properties.
CC   -!- Belongs to peptidase family S8A.
PR   PROSITE; PDOC00125;
DR   P58099, C5AP_STRP1 ;  P0DD34, C5AP_STRP3 ;  Q5X9R0, C5AP_STRP6 ;
DR   Q8NZ80, C5AP_STRP8 ;  P0DD35, C5AP_STRPQ ;  P15926, C5AP_STRPY ;
//
ID   3.4.21.111
DE   Aqualysin 1.
AN   Caldolysin.
CA   Exhibits low specificity toward esters of amino acids with small
CA   hydrophobic or aromatic residues at the P1 position.
CC   -!- This enzyme from the extreme thermophile, Thermus aquaticus, is an
CC       alkaline serine peptidase.
CC   -!- It has three subsites, S1, S2, and S3, in the substrate binding site.
CC   -!- The preferred amino acids at the S1 site are Ala and Phe, at the S2
CC       site are Ala and norleucine and at the S3 site are Phe and Ile.
CC   -!- These specificities are similar to those of EC 3.4.21.62 and
CC       EC 3.4.21.64.
CC   -!- The enzyme displays broad specificity for cleavage of insulin B-chain
CC       and hydrolyzes elastin substrates such as succinyl-(Ala)(n)-p-
CC       nitroanilide (n = 1,2,3) and some peptide esters.
CC   -!- Belongs to peptidase family S8A.
PR   PROSITE; PDOC00125;
DR   P08594, AQL1_THEAQ ;
//
ID   3.4.21.112
DE   Site-1 protease.
AN   Mammalian subtilisin/kexin isozyme 1.
AN   Membrane-bound transcription factor site-1 protease.
AN   Proprotein convertase SKI-1.
AN   Proprotein convertase SKI-1/S1PPS1.
AN   S1P endopeptidase.
AN   S1P protease.
AN   Site-1 peptidase.
AN   SKI-1.
AN   SREBP proteinase.
AN   SREBP S1 protease.
AN   SREBP-1 proteinase.
AN   SREBP-2 proteinase.
AN   Sterol regulatory element-binding protein proteinase.
AN   Sterol regulatory element-binding protein site 1 protease.
AN   Sterol-regulated luminal protease.
AN   Subtilase SKI-1.
AN   Subtilase SKI-1/S1P.
AN   Subtilisin/kexin isozyme 1.
CA   Processes precursors containing basic and hydrophobic/aliphatic residues
CA   at P4 and P2, respectively, with a relatively relaxed acceptance of amino
CA   acids at P1 and P3.
CC   -!- Cleaves sterol regulatory element-binding proteins (SREBPs) and
CC       thereby initiates a process by which the active fragments of the
CC       SREBPs translocate to the nucleus and activate genes controlling the
CC       synthesis and uptake of cholesterol and unsaturated fatty acids into
CC       the bloodstream.
CC   -!- The enzyme also processes pro-brain-derived neurotrophic factor and
CC       undergoes autocatalytic activation in the endoplasmic reticulum
CC       through sequential cleavages.
CC   -!- The enzyme can also process the unfolded protein response stress
CC       factor ATF6 at an Arg-His-Lys-Lys-|- site, and the envelope
CC       glycoprotein of the highly infectious Lassa virus and Crimean Congo
CC       hemorrhagic fever virus at Arg-Arg-Lys-Lys-|-.
CC   -!- Belongs to peptidase family S8A.
PR   PROSITE; PDOC00125;
DR   Q9Z2A8, MBTP1_CRIGR;  Q14703, MBTP1_HUMAN;  Q9WTZ2, MBTP1_MOUSE;
DR   Q9WTZ3, MBTP1_RAT  ;
//
ID   3.4.21.113
DE   Pestivirus NS3 polyprotein peptidase.
AN   BDV NS3 endopeptidase.
AN   Border disease virus NS3 endopeptidase.
AN   Bovine viral diarrhea virus NS3 endopeptidase.
AN   BVDV NS3 endopeptidase.
AN   Classical swine fever virus NS3 endopeptidase.
AN   CSFV NS3 endopeptidase.
CA   Leu is conserved at position P1 for all four cleavage sites. Alanine is
CA   found at position P1' of the NS4A-NS4B cleavage site, whereas serine is
CA   found at position P1' of the NS3-NS4A, NS4B-NS5A and NS5A-NS5B cleavage
CA   sites.
CC   -!- The polyprotein of noncytopathogenic pestiviruses is cleaved co- and
CC       post-translationally into at least 11 proteins (N(pro), C, E(rns),
CC       E1, E2, p7, NS2-3, NS4A, NS4B, NS5A, and NS5B).
CC   -!- The genomes of cytopathogenic pestivirus strains express at least one
CC       additional protein, called NS3 (p80).
CC   -!- This enzyme, which resides in the N-terminal region of NS3
CC       (nonstructural protein 3), is essential for generation of its own
CC       C-terminus and for processing of the downstream cleavage sites,
CC       leading to the release of the pestivirus nonstructural proteins NS4A,
CC       NS4B, NS5A and NS5B.
CC   -!- Belongs to peptidase family S31.
DR   Q96662, POLG_BVDVC ;  P19711, POLG_BVDVN ;  Q01499, POLG_BVDVS ;
DR   P19712, POLG_CSFVA ;  P21530, POLG_CSFVB ;
//
ID   3.4.21.114
DE   Equine arterivirus serine peptidase.
AN   3C-like Ser protease.
AN   3C-like serine protease.
AN   3CLSP.
AN   Arterivirus NSP4.
AN   Chymotrypsin-like serine proteinase nsp4.
AN   Equine arteritis virus serine peptidase.
AN   Nonstructural protein 4 serine protease.
CA   Cleavage of (Glu/Gln)-|-(Gly/Ser/Ala) in arterivirus replicase
CA   translation products ORF1a and ORF1ab.
CC   -!- In the equine arterivirus (EAV), the replicase gene is translated
CC       into open reading frame 1a (ORF1a) and ORF1ab polyproteins.
CC   -!- This enzyme is the main viral proteinase and processes five cleavage
CC       sites in the ORF1a protein and three in the ORF1b-encoded part of the
CC       ORF1ab protein to yield nonstructural proteins (nsp5-nsp12).
CC   -!- It combines the catalytic system of a chymotrypsin-like serine
CC       peptidase (His-Asp-Ser catalytic triad) with the substrate
CC       specificity of a 3C-like serine peptidase (Glu or Gln) at the P1
CC       position and a small amino-acid residue (Gly, Ser or Ala) at the P1'
CC       position.
CC   -!- Cleavage of ORF1ab by this enzyme is essential for viral replication.
CC   -!- Belongs to peptidase family S32.
//
ID   3.4.21.115
DE   Infectious pancreatic necrosis birnavirus Vp4 peptidase.
AN   Infectious pancreatic necrosis virus protease.
AN   IPNV Vp4 peptidase.
AN   IPNV Vp4 protease.
AN   NS protease.
AN   NS-associated protease.
AN   Vp4 protease.
CA   Cleaves the (Ser/Thr)-Xaa-Ala-|-(Ser/Ala)-Gly motif in the polyprotein
CA   NH(2)-pVP2-VP4-VP3-COOH of infectious pancreatic necrosis virus at the
CA   pVP2-VP4 and VP4-VP3 junctions.
CC   -!- Infectious pancreatic necrosis virus (IPNV) is a birnavirus that
CC       causes an acute, contagious disease in young salmonid fish.
CC   -!- As with most viruses that infect eukaryotic cells, the proteolytic
CC       processing of viral precursor proteins is a crucial step in the life
CC       cycle of this virus.
CC   -!- pVP2 is converted into VP2 by cleavage near the carboxy end of pVP2;
CC       this cleavage is most likely due to host-cell proteases rather than
CC       VP4.
CC   -!- Differs from most serine peptidases in not having the catalytic triad
CC       Ser-His-Asp.
CC   -!- Belongs to peptidase family S50.
//
ID   3.4.21.116
DE   SpoIVB peptidase.
AN   Sporulation factor IV B protease.
AN   Stage IV sporulation protein B.
CA   Self-cleaves 52-Val-|-Asn-53, 62-Ala-|-Phe-63 and 74-Val-|-Thr-75 at the
CA   N-terminus of SpoIVB.
CC   -!- This enzyme plays a central role in a regulatory checkpoint (the
CC       sigma(K) checkpoint), which coordinates gene expression during the
CC       later stages of spore formation in Bacillus subtilis.
CC   -!- The enzyme activates proteolytic processing of a sporulation-specific
CC       sigma factor, pro-sigma(K), to its mature and active form, sigma(K),
CC       by self-cleavage.
CC   -!- The enzyme is also subject to secondary proteolysis, which presumably
CC       inactivates SpoIVB.
CC   -!- The enzyme is also essential for the formation of heat-resistant
CC       spores.
CC   -!- Belongs to peptidase family S55.
PR   PROSITE; PDOC51494;
DR   P17896, SP4B_BACSU ;
//
ID   3.4.21.117
DE   Stratum corneum chymotryptic enzyme.
AN   Kallikrein 7.
AN   SCCE.
AN   Serine protease 6.
CA   Cleavage of proteins with aromatic side chains in the P1 position.
CC   -!- This enzyme has wide substrate specificity, being able to degrade
CC       heat-denatured bovine casein and the alpha-chain of native human
CC       fibrinogen.
CC   -!- It cleaves the B chain of bovine insulin at 6-Leu-|-Cya-7 (cysteic
CC       acid), 16-Tyr-|-Leu-17, 25-Phe-|-Tyr-26 and 26-Tyr-|-Thr-27.
CC   -!- It is thought to play a role in the desquamation (skin-shedding) of
CC       the outer layer of skin, the stratum corneum, by degrading
CC       intercellular cohesive structures.
CC   -!- Belongs to peptidase family S1A.
PR   PROSITE; PDOC00124;
DR   P49862, KLK7_HUMAN ;  Q91VE3, KLK7_MOUSE ;
//
ID   3.4.21.118
DE   Kallikrein 8.
AN   Neuropsin.
AN   Ovasin.
AN   Serine protease 19.
AN   TADG-14.
AN   Tumor-associated differentially expressed gene 14.
CA   Cleavage of amide substrates following the basic amino acids Arg or Lys
CA   at the P1 position, with a preference for Arg over Lys.
CC   -!- Activated by removal of an N-terminal prepropeptide.
CC   -!- The highest amidolytic activity is observed using Boc-Val-Pro-
CC       Arg-|-7-amido-4-methylcoumarin, which is a substrate of alpha-
CC       thrombin.
CC   -!- Substrates lacking basic amino acids in the P1 position are not
CC       cleaved.
CC   -!- Degrades casein, fibronectin, gelatin, collagen type IV, fibrinogen,
CC       and high-molecular-mass kininogen and is associated with diseases
CC       such as ovarian cancer and Alzheimer's disease.
CC   -!- Belongs to peptidase family S1A.
PR   PROSITE; PDOC00124;
DR   O60259, KLK8_HUMAN ;  Q61955, KLK8_MOUSE ;  O88780, KLK8_RAT   ;
//
ID   3.4.21.119
DE   Kallikrein 13.
AN   Epidermal growth factor-binding protein type B.
AN   MGK-13.
AN   PRECE.
AN   PRECE-1.
AN   Prorenin converting enzyme 1.
AN   Prorenin-converting enzyme.
AN   Proteinase P.
CA   Hydrolyzes mouse Ren2 protein (a species of prorenin present in the
CA   submandibular gland) on the carboxy side of the arginine residue at the
CA   Lys-Arg-|- pair in the N-terminus, to yield mature renin.
CC   -!- Specific for prorenin from the mouse submandibular gland, as prorenin
CC       from the mouse kidney (Ren1) and human prorenin are not substrates.
CC   -!- Site-directed mutagenesis studies have shown that the enzyme will
CC       also cleave prorenin when Lys-Arg is replaced by Arg-Arg or Gln-Arg
CC       but the rate of reaction is much slower when Lys-Lys is used.
CC   -!- Also able to process pro-interleukin-1-beta (pro-IL-1-beta) in mouse
CC       submandibular gland to form IL-1-beta.
CC   -!- Belongs to peptidase family S1A.
PR   PROSITE; PDOC00124;
DR   P36368, EGFB2_MOUSE;
//
ID   3.4.21.120
DE   Oviductin.
AN   Oviductal protease.
AN   Ovochymase-2.
CA   Preferential cleavage at 371-Gly-Ser-Arg-|-Trp-374 of glycoprotein gp43
CA   in Xenopus laevis coelemic egg envelope to yield gp41.
CC   -!- The egg envelope of Xenopus laevis is modified during transit of the
CC       egg through the pars rectus oviduct, changing the egg envelope from
CC       an unfertilizable form to a fertilizable form.
CC   -!- This process involves the conversion of glycoprotein gp43 to gp41
CC       (ZPC) by the pars recta protease oviductin.
CC   -!- It is thought that the enzymatically active protease molecule
CC       comprises the N-terminal protease domain coupled to two C-terminal
CC       CUB domains, which are related to the mammalian spermadhesin
CC       molecules implicated in mediating sperm-envelope interactions.
CC   -!- Also found in Bufo japonicus.
CC   -!- Belongs to peptidase family S1.
PR   PROSITE; PDOC00124;
DR   Q66TN7, OVCH2_BUFAR;  Q90WD8, OVCH2_BUFJA;  P79953, OVCH2_XENLA;
//
ID   3.4.22.1
DE   Cathepsin B.
AN   Cathepsin B1.
CA   Hydrolysis of proteins with broad specificity for peptide bonds.
CA   Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates
CA   (thus differing from cathepsin L). In addition to being an endopeptidase,
CA   shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.
CC   -!- An intracellular (lysosomal) enzyme.
CC   -!- Belongs to peptidase family C1.
PR   PROSITE; PDOC00126;
DR   P07688, CATB_BOVIN ;  P43233, CATB_CHICK ;  P81494, CATB_COTJA ;
DR   P07858, CATB_HUMAN ;  Q4R5M2, CATB_MACFA ;  P10605, CATB_MOUSE ;
DR   A1E295, CATB_PIG   ;  Q5R6D1, CATB_PONAB ;  P00787, CATB_RAT   ;
DR   P83205, CATB_SHEEP ;  Q54QD9, CTSB_DICDI ;
//
ID   3.4.22.2
DE   Papain.
AN   Papaya peptidase I.
CA   Hydrolysis of proteins with broad specificity for peptide bonds,
CA   but preference for an amino acid bearing a large hydrophobic side chain
CA   at the P2 position. Does not accept Val in P1'.
CC   -!- From latex of the papaya (Carica papaya).
CC   -!- Inhibited by compound E-64 and proteins of the cystatin family.
CC   -!- Belongs to peptidase family C1.
CC   -!- Formerly EC 3.4.4.10.
PR   PROSITE; PDOC00126;
DR   P00784, PAPA1_CARPA;
//
ID   3.4.22.3
DE   Ficain.
AN   Ficin.
CA   Specificity similar to that of papain.
CC   -!- The major proteolytic component of the latex of fig, Ficus glabrata.
CC   -!- Cysteine endopeptidases with similar properties are present in other
CC       members of the large genus Ficus.
CC   -!- Belongs to peptidase family C1.
CC   -!- Formerly EC 3.4.4.12.
PR   PROSITE; PDOC00126;
//
ID   3.4.22.4
DE   Transferred entry: 3.4.22.32 and 3.4.22.33.
//
ID   3.4.22.5
DE   Transferred entry: 3.4.22.33.
//
ID   3.4.22.6
DE   Chymopapain.
AN   Papaya proteinase II.
CA   Specificity similar to that of papain.
CC   -!- The major endopeptidase of papaya (Carica papaya) latex.
CC   -!- It has multiple chromatographic forms.
CC   -!- Belongs to peptidase family C1.
CC   -!- Formerly EC 3.4.4.11.
PR   PROSITE; PDOC00126;
DR   P14080, PAPA2_CARPA;
//
ID   3.4.22.7
DE   Asclepain.
CA   Specificity similar to that of papain.
CC   -!- From the latex of milkweed, Asclepias syriaca.
CC   -!- It has multiple forms.
CC   -!- Belongs to peptidase family C1.
//
ID   3.4.22.8
DE   Clostripain.
AN   Clostridiopeptidase B.
CA   Preferential cleavage: Arg-|-Xaa, including Arg-|-Pro bond, but not
CA   Lys-|-Xaa.
CC   -!- From the bacterium Clostridium histolyticum.
CC   -!- Activated by calcium; inhibited by EDTA.
CC   -!- Belongs to peptidase family C11.
CC   -!- Formerly EC 3.4.4.20.
DR   P09870, CLOS_CLOHI ;
//
ID   3.4.22.9
DE   Transferred entry: 3.4.21.48.
//
ID   3.4.22.10
DE   Streptopain.
AN   Streptococcal cysteine proteinase.
AN   Streptococcal proteinase.
AN   Streptococcus peptidase A.
CA   Preferential cleavage with hydrophobic residues at P2, P1 and P1'.
CC   -!- From the bacterium, group A Streptococcus.
CC   -!- Formed from the proenzyme by limited proteolysis.
CC   -!- Belongs to peptidase family C10.
CC   -!- Formerly EC 3.4.4.18.
DR   P0C0J1, SPEB_STRP1 ;  P0DD38, SPEB_STRP3 ;  Q5X9P3, SPEB_STRP6 ;
DR   P68885, SPEB_STRP8 ;  Q48R29, SPEB_STRPM ;  P0DD39, SPEB_STRPQ ;
DR   P0C0J0, SPEB_STRPY ;
//
ID   3.4.22.11
DE   Transferred entry: 3.4.24.56.
//
ID   3.4.22.12
DE   Transferred entry: 3.4.19.9.
//
ID   3.4.22.13
DE   Deleted entry.
//
ID   3.4.22.14
DE   Actinidain.
AN   Actinidia anionic protease.
AN   Actinidin.
CA   Specificity close to that of papain.
CC   -!- From the kiwi fruit or Chinese gooseberry (Actinidia chinensis).
CC   -!- Belongs to peptidase family C1.
PR   PROSITE; PDOC00126;
DR   P00785, ACTN_ACTCH ;  A5HII1, ACTN_ACTDE ;
//
ID   3.4.22.15
DE   Cathepsin L.
CA   Specificity close to that of papain. As compared to cathepsin B,
CA   cathepsin L exhibits higher activity toward protein substrates, but has
CA   little activity on Z-Arg-Arg-NHMec, and no peptidyl-dipeptidase activity.
CC   -!- A lysosomal enzyme that is readily inhibited by the diazomethane
CC       inhibitor Z-Phe-Phe-CHN(2) or the epoxide inhibitor E-64.
CC   -!- Belongs to peptidase family C1.
PR   PROSITE; PDOC00126;
DR   P25975, CATL1_BOVIN;  Q9GL24, CATL1_CANFA;  P09648, CATL1_CHICK;
DR   Q9GKL8, CATL1_CHLAE;  Q09093, CATL1_FASHE;  P25773, CATL1_FELCA;
DR   P07711, CATL1_HUMAN;  P06797, CATL1_MOUSE;  Q94714, CATL1_PARTE;
DR   Q28944, CATL1_PIG  ;  P07154, CATL1_RAT  ;  Q10991, CATL1_SHEEP;
DR   P80342, CATL2_FASHE;  A0E358, CATL2_PARTE;  P80532, CATL3_FASHE;
DR   Q94715, CATL3_PARTE;  O17473, CATL_BRUPA ;  Q95029, CATL_DROME ;
DR   Q26636, CATL_SARPE ;  Q26534, CATL_SCHMA ;
//
ID   3.4.22.16
DE   Cathepsin H.
AN   Aleurain.
AN   Cathepsin B3.
AN   Cathepsin BA.
AN   N-benzoylarginine-beta-naphthylamide hydrolase.
CA   Hydrolysis of proteins, acting as an aminopeptidase (notably, cleaving
CA   Arg-|-Xaa bonds) as well as an endopeptidase.
CC   -!- Present in lysosomes of mammalian cells.
CC   -!- Because of the combination of endopeptidase and aminopeptidase
CC       activity it can be considered as 'endoaminopeptidase'.
CC   -!- Belongs to peptidase family C1.
PR   PROSITE; PDOC00126;
DR   Q8RWQ9, ALEUL_ARATH;  Q8H166, ALEU_ARATH ;  P05167, ALEU_HORVU ;
DR   Q3T0I2, CATH_BOVIN ;  P09668, CATH_HUMAN ;  P49935, CATH_MOUSE ;
DR   O46427, CATH_PIG   ;  P00786, CATH_RAT   ;
//
ID   3.4.22.17
DE   Transferred entry: 3.4.22.52 and 3.4.22.53.
//
ID   3.4.22.18
DE   Transferred entry: 3.4.21.26.
//
ID   3.4.22.19
DE   Transferred entry: 3.4.24.15.
//
ID   3.4.22.20
DE   Deleted entry.
//
ID   3.4.22.21
DE   Transferred entry: 3.4.25.1.
//
ID   3.4.22.22
DE   Transferred entry: 3.4.24.37.
//
ID   3.4.22.23
DE   Transferred entry: 3.4.21.61.
//
ID   3.4.22.24
DE   Cathepsin T.
CA   Interconversion of the three forms of EC 2.6.1.5.
CC   -!- Degrades azocasein and denatured hemoglobin; the only native protein
CC       on which it has been shown to act is EC 2.6.1.5.
//
ID   3.4.22.25
DE   Glycyl endopeptidase.
AN   Papaya peptidase B.
AN   Papaya proteinase IV.
CA   Preferential cleavage: Gly-|-Xaa, in proteins and in small molecule
CA   substrates.
CC   -!- From the papaya plant, Carica papaya.
CC   -!- Not inhibited by chicken cystatin, unlike most other homologs of
CC       papain.
CC   -!- Belongs to peptidase family C1.
PR   PROSITE; PDOC00126;
DR   P05994, PAPA4_CARPA;
//
ID   3.4.22.26
DE   Cancer procoagulant.
CA   Specific cleavage of Arg-|-Ile bond in Factor X to form Factor Xa.
CC   -!- Apparently produced only by malignant and fetal cells.
//
ID   3.4.22.27
DE   Cathepsin S.
CA   Similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec,
CA   and more activity on the Z-Val-Val-Arg-|-Xaa compound.
CC   -!- A lysosomal cysteine endopeptidase that is unusual among such enzymes
CC       for its stability to neutral pH.
CC   -!- Belongs to peptidase family C1.
PR   PROSITE; PDOC00126;
DR   P25326, CATS_BOVIN ;  Q8HY81, CATS_CANFA ;  P25774, CATS_HUMAN ;
DR   O70370, CATS_MOUSE ;  Q02765, CATS_RAT   ;  Q8HY82, CATS_SAIBB ;
//
ID   3.4.22.28
DE   Picornain 3C.
AN   Foot-and-mouth protease 3C.
AN   Picornavirus endopeptidase 3C.
AN   Poliovirus protease 3C.
AN   Rhinovirus protease 3C.
CA   Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In
CA   other picornavirus reactions Glu may be substituted for Gln, and Ser or
CA   Thr for Gly.
CC   -!- From entero-, rhino-, aphto- and cardioviruses.
CC   -!- Larger than the homologous virus picornain 2A.
CC   -!- Belongs to peptidase family C3.
DR   Q9YLS4, POLG_AEVCA ;  Q6WQ42, POLG_AEVL2 ;  Q6R325, POLG_AEVVR ;
DR   P12915, POLG_BOVEV ;  Q65900, POLG_CX16G ;  Q9QF31, POLG_CX16T ;
DR   P22055, POLG_CXA21 ;  P36290, POLG_CXA24 ;  P21404, POLG_CXA9  ;
DR   P08291, POLG_CXB1J ;  Q9YLG5, POLG_CXB2O ;  P03313, POLG_CXB3N ;
DR   Q66282, POLG_CXB3W ;  Q86887, POLG_CXB4E ;  P08292, POLG_CXB4J ;
DR   Q03053, POLG_CXB5P ;  Q9QL88, POLG_CXB6S ;  O91734, POLG_EC01F ;
DR   Q9YLJ1, POLG_EC05N ;  Q66474, POLG_EC06C ;  Q66577, POLG_EC09B ;
DR   Q66849, POLG_EC09H ;  P29813, POLG_EC11G ;  Q66575, POLG_EC12T ;
DR   Q9WN78, POLG_EC30B ;  P08490, POLG_ECHO9 ;  P03304, POLG_EMCV  ;
DR   P17593, POLG_EMCVB ;  P17594, POLG_EMCVD ;  P12296, POLG_ENMGO ;
DR   P03306, POLG_FMDV1 ;  P03308, POLG_FMDVA ;  P03305, POLG_FMDVO ;
DR   P03311, POLG_FMDVS ;  P49303, POLG_FMDVZ ;  Q8V0N6, POLG_HAV88 ;
DR   Q5Y944, POLG_HAVCF ;  Q67825, POLG_HAVGB ;  A3FMB2, POLG_HAVH2 ;
DR   Q05794, POLG_HAVHA ;  P08617, POLG_HAVHM ;  A5LGW7, POLG_HAVJ8 ;
DR   P06441, POLG_HAVLA ;  P13901, POLG_HAVMB ;  Q9DWR1, POLG_HAVNO ;
DR   P14553, POLG_HAVS2 ;  P32537, POLG_HE701 ;  Q66478, POLG_HE71B ;
DR   Q66479, POLG_HE71M ;  Q66578, POLG_HPE1H ;  Q9YID8, POLG_HPE23 ;
DR   O73556, POLG_HPE2W ;  P03303, POLG_HRV14 ;  Q82122, POLG_HRV16 ;
DR   P12916, POLG_HRV1B ;  P04936, POLG_HRV2  ;  P07210, POLG_HRV8A ;
DR   O41174, POLG_PEV9U ;  P03300, POLG_POL1M ;  P03301, POLG_POL1S ;
DR   P06210, POLG_POL2L ;  P23069, POLG_POL2W ;  P06209, POLG_POL32 ;
DR   P03302, POLG_POL3L ;  P16604, POLG_SVDVH ;  P13900, POLG_SVDVU ;
DR   P08544, POLG_TMEVB ;  P13899, POLG_TMEVD ;  P08545, POLG_TMEVG ;
//
ID   3.4.22.29
DE   Picornain 2A.
AN   Picornavirus endopeptidase 2A.
AN   Poliovirus protease 2A.
AN   Rhinovirus protease 2A.
CA   Selective cleavage of Tyr-|-Gly bond in the picornavirus polyprotein.
CC   -!- From entero- and rhinoviruses.
CC   -!- Smaller than the homologous virus picornain 3C.
CC   -!- Belongs to peptidase family C3.
DR   P12915, POLG_BOVEV ;  Q65900, POLG_CX16G ;  Q9QF31, POLG_CX16T ;
DR   P22055, POLG_CXA21 ;  P36290, POLG_CXA24 ;  P21404, POLG_CXA9  ;
DR   P08291, POLG_CXB1J ;  Q9YLG5, POLG_CXB2O ;  P03313, POLG_CXB3N ;
DR   Q66282, POLG_CXB3W ;  Q86887, POLG_CXB4E ;  P08292, POLG_CXB4J ;
DR   Q03053, POLG_CXB5P ;  Q9QL88, POLG_CXB6S ;  O91734, POLG_EC01F ;
DR   Q9YLJ1, POLG_EC05N ;  Q66474, POLG_EC06C ;  Q66577, POLG_EC09B ;
DR   Q66849, POLG_EC09H ;  P29813, POLG_EC11G ;  Q66575, POLG_EC12T ;
DR   Q66790, POLG_EC16H ;  Q9WN78, POLG_EC30B ;  P32537, POLG_HE701 ;
DR   Q66478, POLG_HE71B ;  Q66479, POLG_HE71M ;  Q66578, POLG_HPE1H ;
DR   Q9YID8, POLG_HPE23 ;  O73556, POLG_HPE2W ;  P03303, POLG_HRV14 ;
DR   Q82122, POLG_HRV16 ;  P12916, POLG_HRV1B ;  P04936, POLG_HRV2  ;
DR   P07210, POLG_HRV8A ;  O41174, POLG_PEV9U ;  P03300, POLG_POL1M ;
DR   P03301, POLG_POL1S ;  P06210, POLG_POL2L ;  P23069, POLG_POL2W ;
DR   P06209, POLG_POL32 ;  P03302, POLG_POL3L ;  P16604, POLG_SVDVH ;
DR   P13900, POLG_SVDVU ;
//
ID   3.4.22.30
DE   Caricain.
AN   Papaya peptidase A.
AN   Papaya peptidase II.
AN   Papaya proteinase III.
AN   Papaya proteinase Omega.
AN   Papaya proteinase Q.
CA   Hydrolysis of proteins with broad specificity for peptide bonds, similar
CA   to those of papain and chymopapain.
CC   -!- From the papaya plant, Carica papaya.
CC   -!- Belongs to peptidase family C1.
PR   PROSITE; PDOC00126;
DR   P10056, PAPA3_CARPA;
//
ID   3.4.22.31
DE   Ananain.
CA   Hydrolysis of proteins with broad specificity for peptide bonds. Best
CA   reported small molecule substrate Bz-Phe-Val-Arg-|-NHMec, but broader
CA   specificity than fruit bromelain.
CC   -!- From stem of pineapple plant, Ananas comosus.
CC   -!- Differs from stem and fruit bromelains in being inhibited by chicken
CC       cystatin.
CC   -!- Belongs to peptidase family C1.
PR   PROSITE; PDOC00126;
DR   P80884, ANAN_ANACO ;
//
ID   3.4.22.32
DE   Stem bromelain.
AN   Bromelain.
CA   Broad specificity for cleavage of proteins, but strong preference for
CA   Z-Arg-Arg-|-NHMec among small molecule substrates.
CC   -!- The most abundant of cysteine endopeptidases of the stem of the
CC       pineapple plant, Ananas comosus.
CC   -!- Distinct from the bromelain found in the pineapple fruit
CC       (EC 3.4.22.33).
CC   -!- Scarcely inhibited by chicken cystatin and also very slowly
CC       inactivated by E-64.
CC   -!- Belongs to peptidase family C1.
CC   -!- Formerly EC 3.4.4.24 and EC 3.4.22.4.
PR   PROSITE; PDOC00126;
DR   P14518, BROM2_ANACO;
//
ID   3.4.22.33
DE   Fruit bromelain.
CA   Hydrolysis of proteins with broad specificity for peptide bonds. Bz-Phe-
CA   Val-Arg-|-NHMec is a good synthetic substrate, but there is no action on
CA   Z-Arg-Arg-|-NHMec (c.f. stem bromelain).
CC   -!- From the pineapple plant, Ananas comosus.
CC   -!- Scarcely inhibited by chicken cystatin.
CC   -!- Another cysteine endopeptidase, with similar action on small molecule
CC       substrates, pinguinain (formerly EC 3.4.99.18), is obtained from the
CC       related plant, Bromelia pinguin, but pinguinain differs from fruit
CC       bromelain in being inhibited by chicken cystatin.
CC   -!- Belongs to peptidase family C1.
CC   -!- Formerly EC 3.4.4.24, EC 3.4.22.4 and EC 3.4.22.5.
PR   PROSITE; PDOC00126;
DR   O23791, BROM1_ANACO;
//
ID   3.4.22.34
DE   Legumain.
AN   Asparaginyl endopeptidase.
AN   Bean endopeptidase.
AN   Hemoglobinase.
AN   Phaseolin.
AN   Vicilin peptidohydrolase.
CA   Hydrolysis of proteins and small molecule substrates at -Asn-|-Xaa-
CA   bonds.
CC   -!- Best known from legume seeds, the trematode Schistosoma mansoni and
CC       mammalian lysosomes.
CC   -!- Not inhibited by compound E-64.
CC   -!- Belongs to peptidase family C13.
PR   PROSITE; PDOC00126;
DR   P80527, HGLB1_FASHE;  P80530, HGLB2_FASHE;  P42665, HGLB_SCHJA ;
DR   P09841, HGLB_SCHMA ;  P49046, LEGU_CANEN ;  Q95M12, LGMN_BOVIN ;
DR   Q99538, LGMN_HUMAN ;  Q4R4T8, LGMN_MACFA ;  O89017, LGMN_MOUSE ;
DR   Q5R5D9, LGMN_PONAB ;  Q9R0J8, LGMN_RAT   ;
//
ID   3.4.22.35
DE   Histolysain.
AN   Histolysin.
CA   Hydrolysis of proteins, including basement membrane collagen and
CA   azocasein. Preferential cleavage: Arg-Arg-|-Xaa in small molecule
CA   substrates including Z-Arg-Arg-|-NHMec.
CC   -!- From the protozoan, Entamoeba histolytica.
CC   -!- Belongs to peptidase family C1.
//
ID   3.4.22.36
DE   Caspase-1.
AN   Interleukin 1-beta converting enzyme.
AN   Interleukin 1-beta-converting endopeptidase.
AN   Interleukin-1 beta convertase precursor.
AN   Interleukin-1-beta convertase.
AN   Pro-interleukin 1-beta proteinase.
AN   Prointerleukin 1-beta protease.
CA   Strict requirement for an Asp residue at position P1 and has a preferred
CA   cleavage sequence of Tyr-Val-Ala-Asp-|-.
CC   -!- Part of the family of inflammatory-caspases, which also includes
CC       caspase-4 (EC 3.4.22.57) and caspase-5 (EC 3.4.22.58) in humans and
CC       caspase-11 (EC 3.4.22.64), caspase-12, caspase-13 and caspase-14 in
CC       mice.
CC   -!- Contains a caspase-recruitment domain (CARD) in its N-terminal
CC       prodomain, which plays a role in procaspase activation.
CC   -!- Cleaves pro-interleukin-1-beta (pro-IL-1-beta) to form mature IL-1-
CC       beta, a potent mediator of inflammation.
CC   -!- Also activates the proinflammatory cytokine, IL-18, which is also
CC       known as interferon-gamma-inducing factor.
CC   -!- Inhibited by Ac-Tyr-Val-Ala-Asp-CHO.
CC   -!- Caspase-11 plays a critical role in the activation of caspase-1 in
CC       mice whereas caspase-4 enhances its activation in humans.
CC   -!- Belongs to peptidase family C14.
PR   PROSITE; PDOC00864;
DR   P55865, CAS1A_XENLA;  P55867, CAS1B_XENLA;  Q9MZV7, CASP1_CANFA;
DR   Q9MZV6, CASP1_FELCA;  Q9TV13, CASP1_HORSE;  P29466, CASP1_HUMAN;
DR   P29452, CASP1_MOUSE;  Q9N2I1, CASP1_PIG  ;  P43527, CASP1_RAT  ;
//
ID   3.4.22.37
DE   Gingipain R.
AN   Arg-gingipain.
AN   Argingipain.
AN   Gingipain-1.
CA   Hydrolysis of proteins and small molecule substrates, with a preference
CA   for Arg in P1.
CC   -!- Strongly activated by glycine and stabilized by calcium.
CC   -!- Belongs to peptidase family C25.
DR   P28784, CPG1_PORGN ;  P95493, CPG2_PORGI ;
//
ID   3.4.22.38
DE   Cathepsin K.
AN   Cathepsin O.
AN   Cathepsin O2.
AN   Cathepsin X.
CA   Broad proteolytic activity. With small-molecule substrates and
CA   inhibitors, the major determinant of specificity is P2, which is
CA   preferably Leu, Met > Phe, and not Arg.
CC   -!- Prominently expressed in mammalian osteoclasts, and believed to play
CC       a role in bone resorption.
CC   -!- Belongs to peptidase family C1.
PR   PROSITE; PDOC00126;
DR   Q5E968, CATK_BOVIN ;  Q3ZKN1, CATK_CANFA ;  Q90686, CATK_CHICK ;
DR   P43235, CATK_HUMAN ;  P61276, CATK_MACFA ;  P61277, CATK_MACMU ;
DR   P55097, CATK_MOUSE ;  Q9GLE3, CATK_PIG   ;  P43236, CATK_RABIT ;
DR   O35186, CATK_RAT   ;
//
ID   3.4.22.39
DE   Adenain.
CA   Cleaves proteins of the adenovirus and its host cell at two consensus
CA   sites: -Yaa-Xaa-Gly-Gly-|-Xaa- and -Yaa-Xaa-Gly-Xaa-|-Gly- (in which Yaa
CA   is Met, Ile or Leu, and Xaa is any amino acid).
CC   -!- A cysteine endopeptidase from adenoviruses.
CC   -!- Activity is greatly stimulated by the binding to the enzyme of an
CC       11-residue peptide from the adenovirus capsid protein pre-VI at a
CC       site separate from the active site.
CC   -!- Belongs to peptidase family C5.
DR   P03252, ADEN_ADE02 ;  P10381, ADEN_ADE03 ;  P07885, ADEN_ADE04 ;
DR   P03253, ADEN_ADE05 ;  Q5TJ03, ADEN_ADE09 ;  P09569, ADEN_ADE12 ;
DR   Q9WF19, ADEN_ADE17 ;  P11825, ADEN_ADE40 ;  P11826, ADEN_ADE41 ;
DR   Q96629, ADEN_ADEB2 ;  P19119, ADEN_ADEB3 ;  O71150, ADEN_ADEB4 ;
DR   P19151, ADEN_ADEB7 ;  O71070, ADEN_ADEBA ;  P68984, ADEN_ADECC ;
DR   P68985, ADEN_ADECR ;  P87563, ADEN_ADECT ;  P68986, ADEN_ADECU ;
DR   O40958, ADEN_ADEE2 ;  Q9IIH4, ADEN_ADEF1 ;  P42672, ADEN_ADEG1 ;
DR   Q9QM72, ADEN_ADEG8 ;  P30202, ADEN_ADEM1 ;  Q83906, ADEN_ADEO7 ;
DR   Q84177, ADEN_ADEP3 ;  Q8JN66, ADEN_ADES1 ;
//
ID   3.4.22.40
DE   Bleomycin hydrolase.
AN   Aminopeptidase C (Lactococcus lactis).
CA   Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis
CA   of a carboxyamide bond of beta-aminoalanine, but also shows general
CA   aminopeptidase activity. The specificity varies somewhat with source,
CA   but amino acid arylamides of Met, Leu and Ala are preferred.
CC   -!- The active sites are on the walls of a central channel through the
CC       molecule, and access of substrate molecules to them is obstructed by
CC       this and by the C-terminus of each polypeptide chain.
CC   -!- Bleomycin can scarcely be the natural substrate, and there are
CC       reports of limited endopeptidase activity.
CC   -!- Known from bacteria as well as eukaryotic organisms.
CC   -!- Hydrolase H from chicken muscle has many similarities to bleomycin
CC       hydrolase, but hydrolyzes Ph-CO-Arg-2-naphthylamine as well as
CC       aminopeptidase substrates.
CC   -!- Belongs to peptidase family C1.
PR   PROSITE; PDOC00126;
DR   B3LP78, BLH1_YEAS1 ;  C7GPC1, BLH1_YEAS2 ;  B5VQH0, BLH1_YEAS6 ;
DR   A6ZRK4, BLH1_YEAS7 ;  C8ZFZ7, BLH1_YEAS8 ;  Q01532, BLH1_YEAST ;
DR   P87362, BLMH_CHICK ;  Q13867, BLMH_HUMAN ;  Q8R016, BLMH_MOUSE ;
DR   P13019, BLMH_RABIT ;  P70645, BLMH_RAT   ;  Q48543, PEPC_LACDL ;
DR   Q10744, PEPC_LACHE ;  Q9CEG3, PEPC_LACLA ;  Q04723, PEPC_LACLC ;
DR   Q928V0, PEPC_LISIN ;  O69192, PEPC_LISMO ;  Q56115, PEPC_STRTR ;
//
ID   3.4.22.41
DE   Cathepsin F.
CA   The recombinant enzyme cleaves synthetic substrates with Phe and Leu
CA   (better than Val) in P2, with high specificity constant (k(cat)/K(m))
CA   comparable to that of cathepsin L.
CC   -!- The enzyme is unstable at neutral pH values and is inhibited by
CC       compound E-64.
CC   -!- Belongs to peptidase family C1.
PR   PROSITE; PDOC00126;
DR   Q9UBX1, CATF_HUMAN ;  Q9R013, CATF_MOUSE ;
//
ID   3.4.22.42
DE   Cathepsin O.
CA   The recombinant human enzyme hydrolyzes synthetic endopeptidase
CA   substrates including Z-Phe-Arg-NHMec and Z-Arg-Arg-NHMec.
CC   -!- The recombinant human enzyme is catalytically active at pH 6.0 and is
CC       inhibited by compound E-64.
CC   -!- Belongs to peptidase family C1.
PR   PROSITE; PDOC00126;
DR   P43234, CATO_HUMAN ;  Q8BM88, CATO_MOUSE ;
//
ID   3.4.22.43
DE   Cathepsin V.
AN   Cathepsin L2.
AN   Cathepsin U.
CA   The recombinant enzyme hydrolyzes proteins (serum albumin, collagen) and
CA   synthetic substrates (Z-Phe-Arg-NHMec > Z-Leu-Arg-NHMec > Z-Val-
CA   Arg-NHMec).
CC   -!- Maximally active at pH 5.7 and unstable at neutral pH.
CC   -!- Compound E-64, leupeptin and chicken cystatin are inhibitors.
CC   -!- Belongs to peptidase family C1.
PR   PROSITE; PDOC00126;
DR   Q5E998, CATL2_BOVIN;  O60911, CATL2_HUMAN;
//
ID   3.4.22.44
DE   Nuclear-inclusion-a endopeptidase.
AN   Potyvirus NIa protease.
CA   Hydrolyzes glutaminyl bonds, and activity is further restricted by
CA   preferences for the amino acids in P6 - P1' that vary with the species of
CA   potyvirus, e.g. Glu-Xaa-Xaa-Tyr-Xaa-Gln-|-(Ser or Gly) for the enzyme
CA   from tobacco etch virus. The natural substrate is the viral polyprotein,
CA   but other proteins and oligopeptides containing the appropriate consensus
CA   sequence are also cleaved.
CC   -!- The potyviruses cause diseases in plants, and inclusion bodies appear
CC       in the host cell nuclei, protein a of these being the endopeptidase.
CC   -!- The enzyme finds practical use when encoded in vectors for the
CC       artificial expression of recombinant fusion proteins, since it can
CC       confer on them the capacity for autolytic cleavage.
CC   -!- It is also reported that transgenic plants expressing the enzyme are
CC       resistant to viral infection.
CC   -!- Belongs to peptidase family C4.
DR   P90245, POL1_BAMMN ;  Q04574, POL1_BAYMG ;  Q01206, POL1_BAYMJ ;
DR   Q9YJW3, POL1_BAYMY ;  Q65399, POLG_BCMNN ;  Q65730, POLG_BSTV1 ;
DR   Q65729, POLG_BSTVG ;  Q6XW15, POLG_BTMV  ;  A0AUJ5, POLG_BVY3  ;
DR   P17765, POLG_BYMV  ;  P89876, POLG_LMV0  ;  P31999, POLG_LMVE  ;
DR   P20234, POLG_OMV   ;  Q01500, POLG_PEMVC ;  O56075, POLG_PEMVM ;
DR   P13529, POLG_PPVD  ;  Q01681, POLG_PPVEA ;  P17766, POLG_PPVNA ;
DR   P17767, POLG_PPVRA ;  Q84934, POLG_PPVSK ;  Q01901, POLG_PRSVH ;
DR   P29152, POLG_PSBMV ;  Q85197, POLG_PVMA  ;  Q02963, POLG_PVYHU ;
DR   P18247, POLG_PVYN  ;  O11436, POLG_RGMVD ;  Q90069, POLG_SBMVG ;
DR   P21231, POLG_SBMVN ;  P89201, POLG_SPMMV ;  P04517, POLG_TEV   ;
DR   A4KZ49, POLG_TRIMV ;  P89509, POLG_TUMVJ ;  Q02597, POLG_TUMVQ ;
DR   P09814, POLG_TVMV  ;  P18478, POLG_WMV2U ;  P18479, POLG_ZYMVC ;
DR   Q89330, POLG_ZYMVR ;  O36979, POLG_ZYMVS ;
//
ID   3.4.22.45
DE   Helper-component proteinase.
AN   HC-Pro.
CA   Hydrolyzes a Gly-|-Gly bond at its own C-terminus, commonly in the
CA   sequence -Tyr-Xaa-Val-Gly-|-Gly, in the processing of the potyviral
CA   polyprotein.
CC   -!- Known from many potyviruses.
CC   -!- The helper component-proteinase of the tobacco etch virus is a
CC       multifunctional protein with several known activities.
CC   -!- The N-terminal region is required for aphid transmission and
CC       efficient genome amplification, the central region is required for
CC       long-distance movement in plants, and the C-terminal domain has
CC       cysteine endopeptidase activity.
CC   -!- Belongs to peptidase family C6.
DR   Q65329, POL2_BAMMA ;  P89684, POL2_BAMMN ;  Q65657, POL2_BAMMU ;
DR   Q01365, POL2_BAYMG ;  Q01207, POL2_BAYMJ ;  Q9YJW2, POL2_BAYMY ;
DR   Q65399, POLG_BCMNN ;  Q65730, POLG_BSTV1 ;  Q6XW15, POLG_BTMV  ;
DR   A0AUJ5, POLG_BVY3  ;  P17765, POLG_BYMV  ;  P89876, POLG_LMV0  ;
DR   P31999, POLG_LMVE  ;  Q01500, POLG_PEMVC ;  O56075, POLG_PEMVM ;
DR   P13529, POLG_PPVD  ;  P17766, POLG_PPVNA ;  P17767, POLG_PPVRA ;
DR   Q84934, POLG_PPVSK ;  Q01901, POLG_PRSVH ;  P29152, POLG_PSBMV ;
DR   Q85197, POLG_PVMA  ;  P22601, POLG_PVYC  ;  Q02963, POLG_PVYHU ;
DR   P18247, POLG_PVYN  ;  P22602, POLG_PVYO  ;  O11436, POLG_RGMVD ;
DR   Q90069, POLG_SBMVG ;  P21231, POLG_SBMVN ;  P89201, POLG_SPMMV ;
DR   P04517, POLG_TEV   ;  A4KZ49, POLG_TRIMV ;  P89509, POLG_TUMVJ ;
DR   Q02597, POLG_TUMVQ ;  P09814, POLG_TVMV  ;  P18479, POLG_ZYMVC ;
DR   Q89330, POLG_ZYMVR ;  O36979, POLG_ZYMVS ;
//
ID   3.4.22.46
DE   L-peptidase.
CA   Autocatalytically cleaves itself from the polyprotein of the foot-
CA   and-mouth disease virus by hydrolysis of a Lys-|-Gly bond, but then
CA   cleaves host cell initiation factor eIF-4G at bonds -Gly-|-Arg- and
CA   -Lys-|-Arg-.
CC   -!- Best known from foot-and-mouth disease virus, but occurs in other
CC       aphthoviruses and cardioviruses.
CC   -!- Destruction of initiation factor eIF-4G has the effect of shutting
CC       off host-cell protein synthesis while allowing synthesis of viral
CC       proteins to continue.
CC   -!- The tertiary structure reveals a distant relationship to papain and,
CC       consistent with this, compound E-64 is inhibitory.
CC   -!- Belongs to peptidase family C28.
DR   P03306, POLG_FMDV1 ;  P03308, POLG_FMDVA ;  P03305, POLG_FMDVO ;
DR   P15072, POLG_FMDVT ;  P49303, POLG_FMDVZ ;
//
ID   3.4.22.47
DE   Gingipain K.
AN   Lys-gingipain.
AN   PrtP proteinase.
CA   Endopeptidase with strict specificity for lysyl bonds.
CC   -!- Activity is stimulated by glycine.
CC   -!- Known from the bacterium Porphyromonas gingivalis and contributes to
CC       the pathogenicity of the organism.
CC   -!- Belongs to peptidase family C25.
DR   P72194, KGP38_PORGN;  P72197, KGP66_PORGN;  Q51817, KGP83_PORGN;
DR   B2RLK2, KGP_PORG3  ;
//
ID   3.4.22.48
DE   Staphopain.
AN   Staphylopain.
CA   Broad endopeptidase action on proteins including elastin, but rather
CA   limited hydrolysis of small-molecule substrates. Assays are conveniently
CA   made with hemoglobin, casein or Z-Phe-Arg-NHMec as substrate.
CC   -!- Known from species of Staphylococcus.
CC   -!- Belongs to peptidase family C47.
PR   PROSITE; PDOC00126;
DR   Q2G2R8, SSPP_STAA8 ;  Q5HEL3, SSPP_STAAC ;  P65825, SSPP_STAAM ;
DR   P65826, SSPP_STAAN ;  Q6GFE8, SSPP_STAAR ;  Q6G824, SSPP_STAAS ;
DR   P81297, SSPP_STAAU ;  Q8NVS9, SSPP_STAAW ;
//
ID   3.4.22.49
DE   Separase.
AN   Separin.
CA   All bonds known to be hydrolyzed by this endopeptidase have arginine in
CA   P1 and an acidic residue in P4. P6 is often occupied by an acidic residue
CA   or by an hydroxy-amino-acid residue, the phosphorylation of which
CA   enhances cleavage.
CC   -!- In both Saccharomyces cerevisiae and human cells, cleavage of the
CC       cohesin subunit Scc1 by separase is required for sister chromatid
CC       separation in mitosis.
CC   -!- S.cerevisiae separase is also known to cleave the Rec8 subunit of a
CC       meiotic cohesin complex and the kinetochore protein Slk19.
CC   -!- Belongs to peptidase family C50.
DR   P33144, BIMB_EMENI ;  P18296, CUT1_SCHPO ;  Q03018, ESP1_YEAST ;
DR   Q14674, ESPL1_HUMAN;  P60330, ESPL1_MOUSE;
//
ID   3.4.22.50
DE   V-cath endopeptidase.
AN   Baculovirus cathepsin.
AN   Viral cathepsin.
CA   Endopeptidase of broad specificity, hydrolyzing substrates of both
CA   cathepsin L and cathepsin B.
CC   -!- Contributes to the liquefaction of the tissues of the insect host in
CC       the late stages of infection by the baculovirus.
CC   -!- Belongs to peptidase family C1.
PR   PROSITE; PDOC00126;
DR   O91466, CATV_GVCPM ;  Q9PYY5, CATV_GVXN  ;  P25783, CATV_NPVAC ;
DR   Q80LP4, CATV_NPVAH ;  Q91CL9, CATV_NPVAP ;  P41721, CATV_NPVBM ;
DR   Q9YWK4, CATV_NPVBS ;  Q6VTL7, CATV_NPVCD ;  P41715, CATV_NPVCF ;
DR   Q91GE3, CATV_NPVEP ;  Q9WGE0, CATV_NPVHC ;  Q8V5U0, CATV_NPVHZ ;
DR   Q9YMP9, CATV_NPVLD ;  Q8QLK1, CATV_NPVMC ;  O10364, CATV_NPVOP ;
DR   Q8B9D5, CATV_NPVR1 ;  Q9J8B9, CATV_NPVSE ;  Q91BH1, CATV_NPVST ;
//
ID   3.4.22.51
DE   Cruzipain.
AN   Congopain.
AN   Cruzain.
AN   Evansain.
AN   Trypanopain.
CA   Broad endopeptidase specificity similar to that of cathepsin L.
CC   -!- Is located in the digestive vacuoles of the parasitic trypanosome and
CC       contributes to the nutrition of the organism by digestion of host
CC       proteins.
CC   -!- Belongs to peptidase family C1.
PR   PROSITE; PDOC00126;
DR   P25779, CYSP_TRYCR ;
//
ID   3.4.22.52
DE   Calpain-1.
AN   Calcium-activated neutral protease I.
AN   Mu-calpain.
CA   Broad endopeptidase specificity.
CF   Calcium.
CC   -!- Cytosolic in animal cells.
CC   -!- The active enzyme molecule is a heterodimer in which the large
CC       subunit contains the peptidase unit, and the small subunit is also a
CC       component of EC 3.4.22.53.
CC   -!- Belongs to peptidase family C2.
CC   -!- Formerly EC 3.4.22.17 and EC 3.4.24.5.
PR   PROSITE; PDOC00126;
DR   Q27970, CAN1_BOVIN ;  P07384, CAN1_HUMAN ;  Q9GLG2, CAN1_MACFA ;
DR   O35350, CAN1_MOUSE ;  P35750, CAN1_PIG   ;  Q5NVS7, CAN1_PONAB ;
DR   P06815, CAN1_RABIT ;  P97571, CAN1_RAT   ;  P00789, CANX_CHICK ;
//
ID   3.4.22.53
DE   Calpain-2.
AN   Calcium-activated neutral protease II.
AN   M-calpain.
AN   Milli-calpain.
CA   Broad endopeptidase specificity.
CF   Calcium.
CC   -!- Cytosolic in animal cells.
CC   -!- The active enzyme molecule is a heterodimer in which the large
CC       subunit contains the peptidase unit, and the small subunit is also a
CC       component of EC 3.4.22.52.
CC   -!- Belongs to peptidase family C2.
CC   -!- Formerly EC 3.4.22.17 and EC 3.4.24.5.
PR   PROSITE; PDOC00126;
DR   Q27971, CAN2_BOVIN ;  Q92178, CAN2_CHICK ;  P17655, CAN2_HUMAN ;
DR   Q9GLG1, CAN2_MACFA ;  O08529, CAN2_MOUSE ;  P43367, CAN2_PIG   ;
DR   P06814, CAN2_RABIT ;  Q07009, CAN2_RAT   ;  A6NHC0, CAN8_HUMAN ;
DR   Q91VA3, CAN8_MOUSE ;  Q78EJ9, CAN8_RAT   ;
//
ID   3.4.22.54
DE   Calpain-3.
AN   Calcium-activated neutral proteinase 3.
AN   Calpain L3.
AN   Calpain p94.
AN   CANP 3.
AN   CAPN3.
AN   Muscle-specific calcium-activated neutral protease 3.
CA   Broad endopeptidase activity.
CF   Calcium.
CC   -!- Activated by autoproteolytic cleavage of insertion sequence 1 (IS1),
CC       which allows substrates and inhibitors gain access to the active
CC       site.
CC   -!- Substrates include the protein itself and connectin/titin.
CC   -!- Belongs to peptidase family C2.
PR   PROSITE; PDOC00126;
PR   PROSITE; PDOC50203;
DR   P51186, CAN3_BOVIN ;  Q92177, CAN3_CHICK ;  P20807, CAN3_HUMAN ;
DR   Q9GLG7, CAN3_MACFA ;  Q64691, CAN3_MOUSE ;  P43368, CAN3_PIG   ;
DR   P16259, CAN3_RAT   ;  Q9TTH8, CAN3_SHEEP ;
//
ID   3.4.22.55
DE   Caspase-2.
AN   CASP-2.
AN   ICH-1.
AN   NEDD-2.
AN   NEDD2 protein.
AN   Neural precursor cell expressed developmentally down-regulated protein 2.
CA   Strict requirement for an Asp residue at P1, with 316-asp being essential
CA   for proteolytic activity and has a preferred cleavage sequence of Val-
CA   Asp-Val-Ala-Asp-|-.
CC   -!- Caspase-2 is an initiator caspase, as are caspases-8 (EC 3.4.22.61),
CC       caspase-9 (EC 3.4.22.62) and caspase-10 (EC 3.4.22.63).
CC   -!- Contains a caspase-recruitment domain (CARD) in its N-terminal
CC       prodomain, which plays a role in procaspase activation.
CC   -!- Two forms of caspase-2 exist that have antagonistic effects: caspase-
CC       2L induces programd cell death and caspase-2S suppresses cell death.
CC   -!- Caspase-2 is activated by caspase-3 (EC 3.4.22.56), or by a caspase-
CC       3-like protease.
CC   -!- Activation involves cleavage of the N-terminal prodomain, followed by
CC       self-proteolysis between the large and small subunits of pro-caspase-
CC       2 and further proteolysis into smaller fragments.
CC   -!- Proteolysis occurs at Asp residues and the preferred substrate for
CC       this enzyme is a pentapeptide rather than a tetrapeptide.
CC   -!- Apart from itself, the enzyme can cleave golgin-16, which is present
CC       in the Golgi complex and has a cleavage site that is unique for
CC       caspase-2.
CC   -!- Alpha-II-spectrin, a component of the membrane cytoskeleton, is a
CC       substrate of the large isoform of pro-caspase-2 (caspase-2L) but not
CC       of the short isoform (caspase-2S).
CC   -!- Belongs to peptidase family C14.
PR   PROSITE; PDOC00864;
DR   Q98943, CASP2_CHICK;  P42575, CASP2_HUMAN;  P29594, CASP2_MOUSE;
DR   P55215, CASP2_RAT  ;
//
ID   3.4.22.56
DE   Caspase-3.
AN   Apopain.
AN   CASP-3.
AN   CPP32.
AN   Yama protein.
CA   Strict requirement for an Asp residue at positions P1 and P4. It has a
CA   preferred cleavage sequence of Asp-Xaa-Xaa-Asp-|- with a hydrophobic
CA   amino-acid residue at P2 and a hydrophilic amino-acid residue at P3,
CA   although Val or Ala are also accepted at this position.
CC   -!- Caspase-3 is an effector/executioner caspase, as are caspase-6
CC       (EC 3.4.22.59) and caspase-7 (EC 3.4.22.60).
CC   -!- These caspases are responsible for the proteolysis of the majority of
CC       cellular polypeptides, (e.g. poly(ADP-ribose) polymerase (PARP)),
CC       which leads to the apoptotic phenotype.
CC   -!- Procaspase-3 can be activated by caspase-1 (EC 3.4.22.36), caspase-8
CC       (EC 3.4.22.61), caspase-9 (EC 3.4.22.62) and caspase-10
CC       (EC 3.4.22.63) as well as by the serine protease granzyme B.
CC   -!- Caspase-3 can activate procaspase-2 (EC 3.4.22.55).
CC   -!- Activation occurs by inter-domain cleavage followed by removal of the
CC       N-terminal prodomain.
CC   -!- While Asp-Glu-(Val/Ile)-Asp is thought to be the preferred cleavage
CC       sequence, the enzyme can accommodate different residues at P2 and P3
CC       of the substrate.
CC   -!- Like caspase-2, a hydrophobic residue at P5 of caspase-3 leads to
CC       more efficient hydrolysis, e.g. (Val/Leu)-Asp-Val-Ala-Asp-|- is a
CC       better substrate than Asp-Val-Ala-Asp-|-.
CC   -!- This is not the case for caspase-7.
CC   -!- Belongs to peptidase family C14.
PR   PROSITE; PDOC00864;
DR   Q08DY9, CASP3_BOVIN;  Q8MKI5, CASP3_CANFA;  Q8MJU1, CASP3_FELCA;
DR   P42574, CASP3_HUMAN;  Q2PFV2, CASP3_MACFA;  Q60431, CASP3_MESAU;
DR   P70677, CASP3_MOUSE;  Q5IS54, CASP3_PANTR;  Q95ND5, CASP3_PIG  ;
DR   Q8MJC3, CASP3_RABIT;  P55213, CASP3_RAT  ;  Q5IS99, CASP3_SAIBB;
DR   P55866, CASP3_XENLA;
//
ID   3.4.22.57
DE   Caspase-4.
AN   CASP-4.
AN   ICE(rel)II.
AN   ICErel-II.
AN   Ich-2.
CA   Strict requirement for Asp at the P1 position. It has a preferred
CA   cleavage sequence of Tyr-Val-Ala-Asp-|- but also cleaves at Asp-Glu-Val-
CA   Asp-|-.
CC   -!- Part of the family of inflammatory-caspases, which also includes
CC       caspase-1 (EC 3.4.22.36) and caspase-5 (EC 3.4.22.58) in humans and
CC       caspase-11 (EC 3.4.22.64), caspase-12, caspase-13 and caspase-14 in
CC       mice.
CC   -!- Contains a caspase-recruitment domain (CARD) in its N-terminal
CC       prodomain, which plays a role in procaspase activation.
CC   -!- Able to cleave itself and the p30 caspase-1 precursor, but, unlike
CC       caspase-1, it is very inefficient at generating mature interleukin-1-
CC       beta (IL-1-beta) from pro-IL-1-beta.
CC   -!- Both this enzyme and caspase-5 can cleave pro-caspase-3 to release
CC       the small subunit (p12) but not the large subunit (p17).
CC   -!- The caspase-1 inhibitor Ac-Tyr-Val-Ala-Asp-CHO can also inhibit this
CC       enzyme, but more slowly.
CC   -!- Belongs to peptidase family C14.
PR   PROSITE; PDOC00864;
DR   Q5E9C1, CASP4_BOVIN;  P49662, CASP4_HUMAN;
//
ID   3.4.22.58
DE   Caspase-5.
AN   CASP-5.
AN   ICErel-III.
AN   Ich-3.
AN   ICH-3 protease.
CA   Strict requirement for Asp at the P1 position. It has a preferred
CA   cleavage sequence of Tyr-Val-Ala-Asp-|- but also cleaves at Asp-Glu-Val-
CA   Asp-|-.
CC   -!- This enzyme is part of the family of inflammatory-caspases, which
CC       also includes caspase-1 (EC 3.4.22.36) and caspase-4 (EC 3.4.22.57)
CC       in humans and caspase-11 (EC 3.4.22.64), caspase-12, caspase-13 and
CC       caspase-14 in mice.
CC   -!- Contains a caspase-recruitment domain (CARD) in its N-terminal
CC       prodomain, which plays a role in procaspase activation.
CC   -!- The enzyme is able to cleave itself and the p30 caspase-1 precursor,
CC       but is very inefficient at generating mature interleukin-1-beta
CC       (IL-1-beta) from pro-IL-1-beta.
CC   -!- Both this enzyme and caspase-4 can cleave pro-caspase-3 to release
CC       the small subunit (p12) but not the large subunit (p17).
CC   -!- Unlike caspase-4, this enzyme can be induced by lipopolysaccharide.
CC   -!- Belongs to peptidase family C14.
PR   PROSITE; PDOC00864;
DR   P51878, CASP5_HUMAN;
//
ID   3.4.22.59
DE   Caspase-6.
AN   Apoptotic protease Mch-2.
AN   CASP-6.
AN   Mch2.
CA   Strict requirement for Asp at position P1 and has a preferred cleavage
CA   sequence of Val-Glu-His-Asp-|-.
CC   -!- Caspase-6 is an effector/executioner caspase, as are caspase-3
CC       (EC 3.4.22.56) and caspase-7 (EC 3.4.22.60).
CC   -!- These caspases are responsible for the proteolysis of the majority of
CC       cellular polypeptides, (e.g. poly(ADP-ribose) polymerase (PARP)),
CC       which lead to the apoptotic phenotype.
CC   -!- Caspase-6 can cleave its prodomain to produce mature caspase-6, which
CC       directly activates caspase-8 (EC 3.4.22.61) and leads to cytochrome c
CC       release from the mitochondria; the release of cytochrome c, which is
CC       an essential component of the intrinsic apoptosis pathway.
CC   -!- Can also cleave and inactivate lamins, the intermediate filament
CC       scaffold proteins of the nuclear envelope, leading to nuclear
CC       fragementation in the final phases of apoptosis.
CC   -!- Belongs to peptidase family C14.
PR   PROSITE; PDOC00864;
DR   Q3T0P5, CASP6_BOVIN;  P55212, CASP6_HUMAN;  O08738, CASP6_MOUSE;
DR   O35397, CASP6_RAT  ;
//
ID   3.4.22.60
DE   Caspase-7.
AN   Apoptotic protease Mch-3.
AN   CASP-7.
AN   CMH-1.
AN   ICE-LAP3.
AN   ICE-like apoptotic protease 3.
AN   Mch3.
CA   Strict requirement for an Asp residue at position P1 and has a preferred
CA   cleavage sequence of Asp-Glu-Val-Asp-|-.
CC   -!- Caspase-7 is an effector/executioner caspase, as are caspase-3
CC       (EC 3.4.22.56) and caspase-6 (EC 3.4.22.59).
CC   -!- These caspases are responsible for the proteolysis of the majority of
CC       cellular polypeptides, (e.g. poly(ADP-ribose) polymerase (PARP)),
CC       which lead to the apoptotic phenotype.
CC   -!- Although a hydrophobic residue at P5 of caspase-2 (EC 3.4.22.55) and
CC       caspase-3 leads to more efficient hydrolysis, the amino-acid residue
CC       at this location in caspase-7 has no effect.
CC   -!- Caspase-7 is activated by the initiator caspases (caspase-8
CC       (EC 3.4.22.61), caspase-9 (EC 3.4.22.62) and caspase-10
CC       (EC 3.4.22.63)).
CC   -!- Removal of the N-terminal prodomain occurs before cleavage in the
CC       linker region between the large and small subunits.
CC   -!- Belongs to peptidase family C14.
PR   PROSITE; PDOC00864;
DR   P55210, CASP7_HUMAN;  P55214, CASP7_MESAU;  P97864, CASP7_MOUSE;
//
ID   3.4.22.61
DE   Caspase-8.
AN   Apoptotic cysteine protease.
AN   Apoptotic protease Mch-5.
AN   CAP4.
AN   CASP-8.
AN   FADD-homologous ICE/CED-3-like protease.
AN   FADD-like ICE.
AN   FLICE.
AN   ICE-like apoptotic protease 5.
AN   MACH.
AN   Mammalian Ced-3 homolog 5.
AN   Mch5.
AN   MORT1-associated CED-3 homolog.
CA   Strict requirement for Asp at position P1 and has a preferred cleavage
CA   sequence of (Leu/Asp/Val)-Glu-Thr-Asp-|-(Gly/Ser/Ala).
CC   -!- Caspase-8 is an initiator caspase, as are caspase-2 (EC 3.4.22.55),
CC       caspase-9 (EC 3.4.22.62) and caspase-10 (EC 3.4.22.63).
CC   -!- Apical activator of the extrinsic (death receptor) apoptosis pathway,
CC       triggered by death receptor ligation.
CC   -!- Contains two tandem death effector domains (DEDs) in its N-terminal
CC       prodomain, which play a role in procaspase activation.
CC   -!- Linked to cell surface death receptors such as Fas.
CC   -!- When Fas is aggregated by the Fas ligand, procaspase-8 is recruited
CC       to the death receptor where it is activated.
CC   -!- Has a preference for Glu at P3 and prefers small residues, such as
CC       Gly, Ser and Ala at the P1' position.
CC   -!- Has very broad P4 specificity, tolerating substrates with Asp, Val or
CC       Leu in this position.
CC   -!- Endogenous substrates for caspase-8 include procaspase-3, the pro-
CC       apoptotic Bcl-2 family member Bid, RIP, PAK2 and the caspase-8
CC       activity modulator FLIP(L).
CC   -!- Belongs to peptidase family C14.
PR   PROSITE; PDOC00864;
DR   Q8IRY7, CASP8_DROME;  Q29IM7, CASP8_DROPS;  Q14790, CASP8_HUMAN;
DR   O89110, CASP8_MOUSE;
//
ID   3.4.22.62
DE   Caspase-9.
AN   APAF-3.
AN   Apoptotic protease Mch-6.
AN   Apoptotic protease-activating factor 3.
AN   CASP-9.
AN   ICE-LAP6.
AN   ICE-like apoptotic protease 6.
CA   Strict requirement for an Asp residue at position P1 and with a marked
CA   preference for His at position P2. It has a preferred cleavage sequence
CA   of Leu-Gly-His-Asp-|-Xaa.
CC   -!- Caspase-9 is an initiator caspase, as are caspase-2 (EC 3.4.22.55),
CC       caspase-8 (EC 3.4.22.61) and caspase-10 (EC 3.4.22.63).
CC   -!- Contains a caspase-recruitment domain (CARD) in its N-terminal
CC       prodomain, which plays a role in procaspase activation.
CC   -!- An alternatively spliced version of caspase-9 also exists, caspase-
CC       9S, that inhibits apoptosis, similar to the situation found with
CC       caspase-2.
CC   -!- Phosphorylation of caspase-9 from some species by Akt, a serine-
CC       threonine protein kinase, inhibits caspase activity in vitro and
CC       caspase activation in vivo.
CC   -!- The activity of caspase-9 is increased dramatically upon association
CC       with the apoptosome but the enzyme can be activated without
CC       proteolytic cleavage.
CC   -!- Procaspase-3 is the enzyme's physiological substrate.
CC   -!- Belongs to peptidase family C14.
PR   PROSITE; PDOC00864;
DR   P55211, CASP9_HUMAN;
//
ID   3.4.22.63
DE   Caspase-10.
AN   Apoptotic protease Mch-4.
AN   CASP-10.
AN   FAS-associated death domain protein interleukin-1-beta-converting enzyme
AN   2.
AN   FLICE2.
AN   ICE-like apoptotic protease 4.
AN   Mch4.
CA   Strict requirement for Asp at position P1 and has a preferred cleavage
CA   sequence of Leu-Gln-Thr-Asp-|-Gly.
CC   -!- Caspase-10 is an initiator caspase, as are caspase-2 (EC 3.4.22.55),
CC       caspase-8 (EC 3.4.22.61) and caspase-9 (EC 3.4.22.62).
CC   -!- Like caspase-8, it contains two tandem death effector domains (DEDs)
CC       in its N-terminal prodomain, which play a role in procaspase
CC       activation.
CC   -!- Has many overlapping substrates in common with caspase-8, such as RIP
CC       (the cleavage of which impairs NF-kappa-B survival signaling and
CC       starts the cell-death process) and PAK2 (associated with some of the
CC       morphological features of apoptosis, such as cell rounding and
CC       apoptotic body formation).
CC   -!- Bid, a Bcl2 protein, can be cleaved by caspase-3 (EC 3.4.22.56),
CC       caspase-8 and caspase-10 at Lys-Gln-Thr-Asp-|- to yield the pro-
CC       apoptotic p15 fragment.
CC   -!- The p15 fragment is N-myristoylated and enhances cytochrome c release
CC       from mitochondria (which initiatiates the intrinsic apoptosis
CC       pathway).
CC   -!- Bid can be further cleaved by caspase-10 and granzyme B but not by
CC       caspase-3 and caspase-8 at Ile-Glu-Thr-Asp-|- to yield a p13 fragment
CC       that is not N-myristoylated.
CC   -!- Belongs to peptidase family C14.
PR   PROSITE; PDOC00864;
DR   Q92851, CASPA_HUMAN;
//
ID   3.4.22.64
DE   Caspase-11.
AN   CASP-11.
CA   Strict requirement for Asp at the P1 position and has a preferred
CA   cleavage sequence of (Ile/Leu/Val/Phe)-Gly-His-Asp-|-.
CC   -!- Part of the family of inflammatory-caspases, which also includes
CC       caspase-1 (EC 3.4.22.36), caspase-4 (EC 3.4.22.57) and caspase-5
CC       (EC 3.4.22.58) in humans and caspase-12, caspase-13 and caspase-14 in
CC       mice.
CC   -!- Contains a caspase-recruitment domain (CARD) in its N-terminal
CC       prodomain, which plays a role in procaspase activation.
CC   -!- Like caspase-5, but unlike caspase-4, this enzyme can be induced by
CC       lipopolysaccharide.
CC   -!- Not only activates caspase-1, which is required for the maturation of
CC       proinflammatory cytokines such as interleukin-1-beta (IL-1-beta) and
CC       IL-18, but it also activates caspase-3 (EC 3.4.22.56), which leads to
CC       cellular apoptosis under pathological conditions.
CC   -!- Belongs to peptidase family C14.
PR   PROSITE; PDOC00864;
DR   P70343, CASP4_MOUSE;
//
ID   3.4.22.65
DE   Peptidase 1 (mite).
AN   Allergen Der p 1.
AN   Endopeptidase 1 (mite).
AN   Major mite fecal allergen Der p 1.
CA   Broad endopeptidase specificity.
CC   -!- This enzyme, derived from the house dust mite, is a major component
CC       of the allergic immune response.
CC   -!- The substrate specificity of this enzyme is not altogether clear; it
CC       cleaves the low-affinity IgE receptor CD23 at 298-Glu-|-Ser-299 and
CC       155-Ser-|-Ser-156.
CC   -!- It also cleaves the pulmonary structural proteins occludin and
CC       claudin at Leu-|-Leu, Asp-|-Leu and at Gly-|-Thr bonds, and it can
CC       also cleave the alpha subunit of the interleukin-2 (IL-2) receptor
CC       (CD25).
CC   -!- Using a positional scanning combinatorial library, it was found that
CC       the major substrate-specificity determinant is for Ala in the P2
CC       position.
CC   -!- The enzyme shows only a slight preference for basic amino acids in
CC       the P1 and P3 positions and a preference for aliphatic amino acids
CC       such as Ile, Pro, Val, Leu and norleucine in the P4 position.
CC   -!- Belongs to peptidase family C1.
DR   P16311, PEPT1_DERFA;  P16312, PEPT1_DERMI;  P08176, PEPT1_DERPT;
DR   P25780, PEPT1_EURMA;  Q1EIQ3, PEPT1_PSOOV;
//
ID   3.4.22.66
DE   Calicivirin.
AN   Calicivirus 3C-like protease.
AN   Calicivirus endopeptidase.
AN   Calicivirus TCP.
AN   Calicivirus trypsin-like cysteine protease.
AN   Camberwell virus processing peptidase.
AN   Chiba virus processing peptidase.
AN   Norovirus virus processing peptidase.
AN   Norwalk virus processing peptidase.
AN   Rabbit hemorrhagic disease virus 3C endopeptidase.
AN   Southampton virus processing peptidase.
CA   Endopeptidase with a preference for cleavage when the P1 position is
CA   occupied by Glu-|-Xaa and the P1' position is occupied by Gly-|-Yaa.
CC   -!- Viruses that are members of the Norovirus genus (Caliciviridae
CC       family) are a major cause of epidemic acute viral gastroenteritis.
CC   -!- The nonstructural proteins of these viruses are produced by
CC       proteolytic cleavage of a large precursor polyprotein, performed by a
CC       protease that is incorporated into the polyprotein.
CC   -!- Cleavage sites are apparently defined by features based on both
CC       sequence and structure since several sites in the polyprotein
CC       fulfilling the identified sequence requirements are not cleaved.
CC   -!- The presence of acidic (Asp), basic (Arg), aromatic (Tyr) or
CC       aliphatic (Leu) amino acids at the P1' position results in only minor
CC       differences in cleavage efficiency, suggesting that steric or
CC       conformational constraints may play a role in determining
CC       specificity.
CC   -!- Changes to the amino acid at the P2 position do not alter cleavage
CC       efficiency.
CC   -!- Belongs to peptidase family C37.
DR   Q288N7, POLG_BECN1 ;  Q8JN60, POLG_BECNB ;  Q8V736, POLG_CACV4 ;
DR   Q96725, POLG_EBHSG ;  P27407, POLG_FCVC6 ;  P27408, POLG_FCVF4 ;
DR   P27409, POLG_FCVF9 ;  Q66914, POLG_FCVUR ;  P54634, POLG_LORDV ;
DR   Q83883, POLG_NVN68 ;  Q9QEJ5, POLG_PESV  ;  P27411, POLG_RHDV3 ;
DR   Q86119, POLG_RHDVA ;  Q89273, POLG_RHDVB ;  P27410, POLG_RHDVF ;
DR   Q86117, POLG_RHDVS ;  P36286, POLG_SMSV1 ;  P36287, POLG_SMSV4 ;
DR   Q04544, POLG_SOUV3 ;  Q6XDK8, POLG_SVM10 ;  Q69014, POLG_SVM93 ;
DR   Q672I1, POLG_SVSAP ;  Q9DUN3, POLG_VESVA ;
//
ID   3.4.22.67
DE   Zingipain.
AN   Ginger protease.
AN   GP-I.
AN   GP-II.
AN   Zingibain.
CA   Preferential cleavage of peptides with a proline residue at the P2
CA   position.
CC   -!- Found in ginger (Zingiber officinale) rhizome and is a member of the
CC       papain family.
CC   -!- The enzyme is inhibited by some divalent metal ions, such as Hg(2+),
CC       Cu(2+), Cd(2+) and Zn(2+).
CC   -!- Belongs to peptidase family C1.
DR   P82473, CPGP1_ZINOF;  P82474, CPGP2_ZINOF;
//
ID   3.4.22.68
DE   Ulp1 peptidase.
AN   Small ubiquitin-related modifier protein 1 conjugate proteinase.
AN   Smt3-protein conjugate proteinase.
AN   SUMO isopeptidase.
AN   SUMO protease.
AN   SUMO-1 conjugate proteinase.
AN   Sumo-1 hydrolase.
AN   SUMO-1-conjugate protease.
AN   SUMO-1-deconjugating enzyme.
AN   SUMO-specific protease.
AN   SUMO-specific proteinase.
AN   Ubl-specific protease 1.
AN   Ulp1.
AN   Ulp1 endopeptidase.
AN   Ulp1 protease.
CA   Hydrolysis of the alpha-linked peptide bond in the sequence Gly-
CA   Gly-|-Ala-Thr-Tyr at the C-terminal end of the small ubiquitin-like
CA   modifier (SUMO) propeptide, Smt3, leading to the mature form of the
CA   protein. A second reaction involves the formation of an epsilon-linked
CA   peptide bond between the C-terminal glycine of the mature SUMO and the
CA   lysine epsilon-amino group of the target protein.
CC   -!- The enzyme from Saccharomyces cerevisiae can also recognize small
CC       ubiquitin-like modifier 1 (SUMO-1) from human as a substrate in both
CC       SUMO-processing (alpha-linked peptide bonds) and SUMO-deconjugation
CC       (epsilon-linked peptide bonds) reactions.
CC   -!- Ulp1 has several functions, including an essential role in
CC       chromosomal segregation and progression of the cell cycle through the
CC       G2/M phase of the cell cycle.
CC   -!- Belongs to peptidase family C48.
PR   PROSITE; PDOC50600;
DR   O42957, ULP1_SCHPO ;  Q02724, ULP1_YEAST ;
//
ID   3.4.22.69
DE   SARS coronavirus main proteinase.
AN   3C-like protease.
AN   3cLpro.
AN   Coronavirus 3C-like protease.
AN   SARS coronavirus main protease.
AN   SARS-CoV 3CLpro enzyme.
AN   Severe acute respiratory syndrome coronavirus main protease.
CA   TSAVLQ-|-SGFRK-NH(2) and SGVTFQ-|-GKFKK the two peptides corresponding to
CA   the two self-cleavage sites of the SARS 3C-like proteinase are the two
CA   most reactive peptide substrates. The enzyme exhibits a strong preference
CA   for substrates containing Gln at P1 position and Leu at P2 position.
CC   -!- SARS coronavirus main protease is the key enzyme in SARS coronavirus
CC       replicase polyprotein processing.
CC   -!- Belongs to peptidase family C30.
DR   P0C6W1, R1AB_BC133 ;  P0C6V9, R1AB_BC279 ;  P0C6W2, R1AB_BCHK3 ;
DR   P0C6W3, R1AB_BCHK4 ;  P0C6W4, R1AB_BCHK5 ;  P0C6W5, R1AB_BCHK9 ;
DR   P0C6W6, R1AB_BCRP3 ;  P0C6W7, R1AB_CVBEN ;  P0C6W8, R1AB_CVBLU ;
DR   P0C6W9, R1AB_CVBM  ;  P0C6X0, R1AB_CVBQ  ;  P0C6X2, R1AB_CVHN1 ;
DR   P0C6X3, R1AB_CVHN2 ;  P0C6X4, R1AB_CVHN5 ;  P0C6X6, R1AB_CVHOC ;
DR   P0C6X7, R1AB_CVHSA ;  P0C6X8, R1AB_CVM2  ;  P0C6X9, R1AB_CVMA5 ;
DR   P0C6Y0, R1AB_CVMJH ;  P0C6F7, R1A_BC133  ;  P0C6F5, R1A_BC279  ;
DR   P0C6F8, R1A_BCHK3  ;  P0C6T4, R1A_BCHK4  ;  P0C6T5, R1A_BCHK5  ;
DR   P0C6T6, R1A_BCHK9  ;  P0C6T7, R1A_BCRP3  ;  P0C6T8, R1A_CVBEN  ;
DR   P0C6T9, R1A_CVBLU  ;  P0C6U0, R1A_CVBM   ;  P0C6U1, R1A_CVBQ   ;
DR   P0C6U3, R1A_CVHN1  ;  P0C6U4, R1A_CVHN2  ;  P0C6U5, R1A_CVHN5  ;
DR   P0C6U7, R1A_CVHOC  ;  P0C6U8, R1A_CVHSA  ;  P0C6U9, R1A_CVM2   ;
DR   P0C6V0, R1A_CVMA5  ;  P0C6V1, R1A_CVMJH  ;
//
ID   3.4.22.70
DE   Sortase A.
CA   The enzyme catalyzes a cell wall sorting reaction in which a surface
CA   protein with a sorting signal containing a LPXTG motif is cleaved between
CA   the Thr and Gly residue. The resulting threonine carboxyl end of the
CA   protein is covalently attached to a pentaglycine cross-bridge of
CA   peptidoglycan.
CC   -!- Belongs to peptidase family C60.
//
ID   3.4.22.71
DE   Sortase B.
AN   SrtB.
CA   The enzyme catalyzes a cell wall sorting reaction in which a surface
CA   protein with a sorting signal containing a NXTN motif is cleaved. The
CA   resulting threonine carboxyl end of the protein is covalently attached to
CA   a pentaglycine cross-bridge of peptidoglycan.
CC   -!- Belongs to peptidase family C60.
//
ID   3.4.23.1
DE   Pepsin A.
AN   Pepsin.
CA   Preferential cleavage: hydrophobic, preferably aromatic, residues in P1
CA   and P1' positions. Cleaves 1-Phe-|-Val-2, 4-Gln-|-His-5, 13-Glu-|-Ala-14,
CA   14-Ala-|-Leu-15, 15-Leu-|-Tyr-16, 16-Tyr-|-Leu-17, 23-Gly-|-Phe-24,
CA   24-Phe-|-Phe-25 and 25-Phe-|-Tyr-26 bonds in the B chain of insulin.
CC   -!- The predominant endopeptidase in the gastric juice of vertebrates,
CC       formed from pepsinogen A by limited proteolysis.
CC   -!- Belongs to peptidase family A1.
CC   -!- Formerly EC 3.4.4.1.
PR   PROSITE; PDOC00128;
DR   P03954, PEPA1_MACFU;  P28712, PEPA1_RABIT;  P27677, PEPA2_MACFU;
DR   P27821, PEPA2_RABIT;  P27822, PEPA3_RABIT;  P27678, PEPA4_MACFU;
DR   P28713, PEPA4_RABIT;  P27823, PEPAF_RABIT;  P00792, PEPA_BOVIN ;
DR   Q9N2D4, PEPA_CALJA ;  Q9GMY6, PEPA_CANFA ;  P00793, PEPA_CHICK ;
DR   P00790, PEPA_HUMAN ;  P11489, PEPA_MACMU ;  P00791, PEPA_PIG   ;
DR   Q9GMY7, PEPA_RHIFE ;  Q9GMY8, PEPA_SORUN ;  P81497, PEPA_SUNMU ;
DR   P13636, PEPA_URSTH ;
//
ID   3.4.23.2
DE   Pepsin B.
AN   Parapepsin I.
CA   Degradation of gelatin; little activity on hemoglobin. Specificity on B
CA   chain of insulin more restricted than that of pepsin A; does not cleave
CA   1-Phe-|-Val-2, 4-Gln-|-His-5 or 23-Gly-|-Phe-24.
CC   -!- Belongs to peptidase family A1.
CC   -!- Formerly EC 3.4.4.2.
PR   PROSITE; PDOC00128;
DR   Q8SQ41, PEPB_CANFA ;  Q10735, PEPB_PIG   ;
//
ID   3.4.23.3
DE   Gastricsin.
AN   Pepsin C.
CA   More restricted specificity than pepsin A, but shows preferential
CA   cleavage at Tyr-|-Xaa bonds. High activity on hemoglobin.
CC   -!- Formed from progastricsin, apparently in the gastric juice of most
CC       vertebrates.
CC   -!- In addition to the fundus, progastricsin is also secreted in antrum
CC       and proximal duodenum.
CC   -!- Seminal plasma contains a zymogen that is immunologically identical
CC       with progastricsin.
CC   -!- Belongs to peptidase family A1.
CC   -!- Formerly EC 3.4.4.22.
PR   PROSITE; PDOC00128;
DR   Q9N2D3, PEPC_CALJA ;  Q64411, PEPC_CAVPO ;  P20142, PEPC_HUMAN ;
DR   P03955, PEPC_MACFU ;  Q689Z7, PEPC_MONDO ;  Q9D7R7, PEPC_MOUSE ;
DR   P30879, PEPC_PIG   ;  Q9GMY2, PEPC_RABIT ;  P04073, PEPC_RAT   ;
DR   Q9GMY3, PEPC_RHIFE ;  Q9GMY4, PEPC_SORUN ;  P81498, PEPC_SUNMU ;
//
ID   3.4.23.4
DE   Chymosin.
AN   Rennin.
CA   Broad specificity similar to that of pepsin A. Clots milk by cleavage of
CA   a single 105-Ser-Phe-|-Met-Ala-108 bond in kappa-chain of casein.
CC   -!- Neonatal gastric enzyme with high milk clotting and weak general
CC       proteolytic activity, formed from prochymosin.
CC   -!- Found among mammals with postnatal uptake of immunoglobins.
CC   -!- Belongs to peptidase family A1.
CC   -!- Formerly EC 3.4.4.3.
PR   PROSITE; PDOC00128;
DR   P00794, CHYM_BOVIN ;  Q9N2D2, CHYM_CALJA ;  P09873, CHYM_FELCA ;
DR   P18276, CHYM_SHEEP ;
//
ID   3.4.23.5
DE   Cathepsin D.
CA   Specificity similar to, but narrower than, that of pepsin A. Does not
CA   cleave the 4-Gln-|-His-5 bond in B chain of insulin.
CC   -!- Occurs intracellularly, in lysosomes.
CC   -!- Belongs to peptidase family A1.
CC   -!- Formerly EC 3.4.4.23.
PR   PROSITE; PDOC00128;
DR   P80209, CATD_BOVIN ;  Q4LAL9, CATD_CANFA ;  Q05744, CATD_CHICK ;
DR   O93428, CATD_CHIHA ;  Q9DEX3, CATD_CLUHA ;  O76856, CATD_DICDI ;
DR   P07339, CATD_HUMAN ;  P18242, CATD_MOUSE ;  P00795, CATD_PIG   ;
DR   P24268, CATD_RAT   ;  Q9MZS8, CATD_SHEEP ;
//
ID   3.4.23.6
DE   Transferred entry: 3.4.21.103, 3.4.23.18, 3.4.23.19, 3.4.23.20,
DE   3.4.23.21, 3.4.23.22, 3.4.23.23, 3.4.23.24, 3.4.23.25, 3.4.23.26,
DE   3.4.23.28 and 3.4.23.30.
//
ID   3.4.23.7
DE   Transferred entry: 3.4.23.20.
//
ID   3.4.23.8
DE   Transferred entry: 3.4.23.25.
//
ID   3.4.23.9
DE   Transferred entry: 3.4.23.21.
//
ID   3.4.23.10
DE   Transferred entry: 3.4.23.22.
//
ID   3.4.23.11
DE   Deleted entry.
//
ID   3.4.23.12
DE   Nepenthesin.
AN   Nepenthes aspartic proteinase.
CA   Similar to pepsin, but also cleaves on either side of Asp and at
CA   Lys-|-Arg.
CC   -!- From the insectivorous plants Nepenthes sp. (secretions) and Drosera
CC       peltata (ground-up leaves).
CC   -!- Aspartic endopeptidases are probably present in many other plants,
CC       including lotus and sorghum.
CC   -!- Formerly EC 3.4.99.4.
DR   P69476, NEP1_NEPDI ;  Q766C3, NEP1_NEPGR ;  P69477, NEP2_NEPDI ;
DR   Q766C2, NEP2_NEPGR ;
//
ID   3.4.23.13
DE   Deleted entry.
//
ID   3.4.23.14
DE   Deleted entry.
//
ID   3.4.23.15
DE   Renin.
AN   Angiotensin-forming enzyme.
AN   Angiotensinogenase.
CA   Cleavage of Leu-|-Xaa bond in angiotensinogen to generate angiotensin I.
CC   -!- Belongs to peptidase family A1.
CC   -!- Formerly EC 3.4.4.15 and EC 3.4.99.19.
PR   PROSITE; PDOC00128;
DR   P06281, RENI1_MOUSE;  P00796, RENI2_MOUSE;  Q9TSZ1, RENI_CALJA ;
DR   Q6DYE7, RENI_CANFA ;  P00797, RENI_HUMAN ;  Q6DLS0, RENI_MACFA ;
DR   Q6DLW5, RENI_MACMU ;  P60016, RENI_PANTR ;  P08424, RENI_RAT   ;
DR   P52115, RENI_SHEEP ;
//
ID   3.4.23.16
DE   HIV-1 retropepsin.
AN   Human immunodeficiency virus type 1 protease.
CA   Specific for a P1 residue that is hydrophobic, and P1' variable,
CA   but often Pro.
CC   -!- Present in human immunodeficiency virus type 1.
CC   -!- Contributes to the maturation of the viral particle, and is a target
CC       of antiviral drugs.
CC   -!- Active enzyme is a dimer of identical 11-kDa subunits.
CC   -!- Similar enzymes occur in other retroviruses.
CC   -!- Belongs to peptidase family A2.
PR   PROSITE; PDOC00128;
DR   O93215, POL_HV190  ;  O12158, POL_HV192  ;  O89290, POL_HV193  ;
DR   Q9QBY3, POL_HV196  ;  Q9QBZ9, POL_HV197  ;  O41798, POL_HV19N  ;
DR   P03369, POL_HV1A2  ;  Q77373, POL_HV1AN  ;  P03366, POL_HV1B1  ;
DR   P04587, POL_HV1B5  ;  Q73368, POL_HV1B9  ;  P03367, POL_HV1BR  ;
DR   P05960, POL_HV1C4  ;  P04589, POL_HV1EL  ;  Q75002, POL_HV1ET  ;
DR   P04585, POL_HV1H2  ;  P12498, POL_HV1J3  ;  P20875, POL_HV1JR  ;
DR   P0C6F2, POL_HV1LW  ;  Q9QBZ1, POL_HV1M2  ;  P04588, POL_HV1MA  ;
DR   P05961, POL_HV1MN  ;  Q9QBZ5, POL_HV1MP  ;  Q79666, POL_HV1MV  ;
DR   P12497, POL_HV1N5  ;  P18802, POL_HV1ND  ;  P20892, POL_HV1OY  ;
DR   P05959, POL_HV1RH  ;  Q9WC54, POL_HV1S2  ;  Q9WC63, POL_HV1S9  ;
DR   O89940, POL_HV1SE  ;  P24740, POL_HV1U4  ;  Q9Q720, POL_HV1V9  ;
DR   Q9QSR3, POL_HV1VI  ;  P35963, POL_HV1Y2  ;  Q9IDV9, POL_HV1YB  ;
DR   O91080, POL_HV1YF  ;  P12499, POL_HV1Z2  ;  P17283, POL_SIVCZ  ;
DR   Q1A249, POL_SIVEK  ;  Q02836, POL_SIVG1  ;  P22382, POL_SIVGB  ;
DR   P05896, POL_SIVM1  ;  Q1A267, POL_SIVMB  ;  P05897, POL_SIVMK  ;
DR   P12502, POL_SIVS4  ;  P19505, POL_SIVSP  ;  Q8AII1, POL_SIVTN  ;
DR   P27973, POL_SIVV1  ;  P27980, POL_SIVVG  ;  P05895, POL_SIVVT  ;
//
ID   3.4.23.17
DE   Pro-opiomelanocortin converting enzyme.
AN   Prohormone converting enzyme.
CA   Cleavage at paired basic residues in certain prohormones, either between
CA   them, or on the carboxyl side.
CC   -!- A 70 kDa membrane-bound enzyme isolated from cattle pituitary
CC       secretory vesicle.
CC   -!- Formerly EC 3.4.99.38.
//
ID   3.4.23.18
DE   Aspergillopepsin I.
AN   Aspergillopepsin A.
AN   Aspergillopepsin F.
AN   Aspergillopeptidase A.
AN   Awamorin.
AN   Proctase B.
AN   Protease type XIII.
AN   Proteinase B.
AN   Trypsinogen kinase.
CA   Hydrolysis of proteins with broad specificity. Generally favors
CA   hydrophobic residues in P1 and P1', but also accepts Lys in P1, which
CA   leads to activation of trypsinogen. Does not clot milk.
CC   -!- Found in a variety of Aspergillus species (imperfect fungi):
CC       A.awamori, A.foetidus, A.fumigatus, A.kawachii, A.niger, A.oryzae,
CC       A.saitoi, and A.sojae.
CC   -!- Belongs to peptidase family A1.
CC   -!- Formerly EC 3.4.23.6.
PR   PROSITE; PDOC00128;
DR   D4ANC3, PEPA_ARTBC ;  E5R1B9, PEPA_ARTGP ;  C5FBS2, PEPA_ARTOC ;
DR   P17946, PEPA_ASPAW ;  A1CBR4, PEPA_ASPCL ;  B0Y1V8, PEPA_ASPFC ;
DR   B8NLY9, PEPA_ASPFN ;  P41748, PEPA_ASPFU ;  A2R3L3, PEPA_ASPNC ;
DR   P55325, PEPA_ASPNG ;  Q06902, PEPA_ASPOR ;  Q12567, PEPA_ASPSA ;
DR   C5PEI9, PEPA_COCP7 ;  O93885, PEPA_EMENI ;  E5A7T3, PEPA_LEPMJ ;
DR   A1DDK1, PEPA_NEOFI ;  B6HL60, PEPA_PENCW ;  P78735, PEPA_PENJA ;
DR   Q01972, PEPA_PENRO ;  Q69IF8, PEPA_PHANO ;  B8MF81, PEPA_TALSN ;
DR   D4D7C5, PEPA_TRIVH ;  Q9HEZ3, PEPB_PENJA ;
//
ID   3.4.23.19
DE   Aspergillopepsin II.
AN   Aspergillus niger var. macrosporus aspartic proteinase.
AN   Proctase A.
AN   Proteinase A.
CA   Preferential cleavage in B chain of insulin: 3-Asn-|-Gln-4, 13-Gly-|-Ala-
CA   14, and 26-Tyr-|-Thr-27.
CC   -!- Isolated from Aspergillus niger var. macrosporus, distinct from
CC       aspergillopepsin I in specificity and insensitivity to pepstatin.
CC   -!- Belongs to peptidase family A4.
CC   -!- Formerly EC 3.4.23.6.
PR   PROSITE; PDOC00128;
DR   P24665, PRTA_ASPNG ;
//
ID   3.4.23.20
DE   Penicillopepsin.
AN   Penicillium janthinellum aspartic protease.
AN   Peptidase A.
CA   Hydrolysis of proteins with broad specificity similar to that of pepsin
CA   A, preferring hydrophobic residues at P1 and P1', but also cleaving
CA   20-Gly-|-Glu-21 in the B chain of insulin. Clots milk, and activates
CA   trypsinogen.
CC   -!- From the imperfect fungus Penicillium janthinellum.
CC   -!- Closely related enzymes have been isolated from P.roqueforti and
CC       P.duponti.
CC   -!- Belongs to peptidase family A1.
CC   -!- Formerly EC 3.4.4.17, EC 3.4.23.6 and EC 3.4.23.7.
PR   PROSITE; PDOC00128;
DR   P00798, PENP_PENJA ;
//
ID   3.4.23.21
DE   Rhizopuspepsin.
AN   Rhizopus aspartic proteinase.
CA   Hydrolysis of proteins with broad specificity similar to that of pepsin
CA   A, preferring hydrophobic residues at P1 and P1'. Clots milk and
CA   activates trypsinogen. Does not cleave 4-Gln-|-His-5, but does cleave
CA   10-His-|-Leu-11 and 12-Val-|-Glu-13 in B chain of insulin.
CC   -!- From the zygomycete fungi Rhizopus chinensis and R.niveus.
CC   -!- Belongs to peptidase family A1.
CC   -!- Formerly EC 3.4.4.17, EC 3.4.23.6, EC 3.4.23.9 and EC 3.4.99.25.
PR   PROSITE; PDOC00128;
DR   P10602, CARP1_RHINI;  P43231, CARP2_RHINI;  Q03699, CARP3_RHINI;
DR   Q03700, CARP4_RHINI;  P43232, CARP5_RHINI;  P06026, CARP_RHICH ;
//
ID   3.4.23.22
DE   Endothiapepsin.
AN   Endothia aspartic proteinase.
CA   Hydrolysis of proteins with specificity similar to that of pepsin A,
CA   prefers hydrophobic residues at P1 and P1', but does not cleave
CA   14-Ala-|-Leu-15 in the B chain of insulin or Z-Glu-Tyr. Clots milk.
CC   -!- From the ascomycete Endothia parasitica.
CC   -!- Belongs to peptidase family A1.
CC   -!- Formerly EC 3.4.4.17, EC 3.4.23.6 and EC 3.4.23.10.
PR   PROSITE; PDOC00128;
DR   P11838, CARP_CRYPA ;
//
ID   3.4.23.23
DE   Mucorpepsin.
AN   Mucor rennin.
CA   Hydrolysis of proteins, favoring hydrophobic residues at P1 and P1'.
CA   Clots milk. Does not accept Lys at P1, and hence does not activate
CA   trypsinogen.
CC   -!- Isolated from the zygomycete fungi Mucor pusillus and M.miehei.
CC   -!- Belongs to peptidase family A1.
CC   -!- Formerly EC 3.4.4.17 and EC 3.4.23.6.
PR   PROSITE; PDOC00128;
DR   P00799, CARP_RHIMI ;  P09177, CARP_RHIPU ;
//
ID   3.4.23.24
DE   Candidapepsin.
AN   Candida albicans aspartic proteinase.
CA   Preferential cleavage at the carboxyl of hydrophobic amino acids,
CA   but fails to cleave 15-Leu-|-Tyr-16, 16-Tyr-|-Leu-17 and 24-Phe-|-Phe-25
CA   of insulin B chain. Activates trypsinogen, and degrades keratin.
CC   -!- This endopeptidase from the imperfect yeast Candida albicans is
CC       inhibited by pepstatin, but not by methyl 2-diazoacetamido-hexanoate
CC       or 1,2-epoxy-3-(p-nitrophenoxy)propane.
CC   -!- Belongs to peptidase family A1.
CC   -!- Formerly EC 3.4.4.17 and EC 3.4.23.6.
PR   PROSITE; PDOC00128;
DR   P28872, CARP1_CANAL;  P32951, CARP1_CANPA;  P28871, CARP2_CANAL;
DR   P32950, CARP2_CANPA;  P43092, CARP3_CANAL;  P43093, CARP4_CANAL;
DR   P43094, CARP5_CANAL;  P43095, CARP6_CANAL;  P43096, CARP7_CANAL;
DR   O42778, CARP8_CANAL;  O42779, CARP9_CANAL;  Q00663, CARP_CANTR ;
//
ID   3.4.23.25
DE   Saccharopepsin.
AN   Saccharomyces aspartic proteinase.
AN   Yeast endopeptidase A.
CA   Hydrolysis of proteins with broad specificity for peptide bonds. Cleaves
CA   -Leu-Leu-|-Val-Tyr- bond in a synthetic substrate. Does not act on esters
CA   of Tyr or Arg.
CC   -!- Located in the vacuole.
CC   -!- Belongs to peptidase family A1.
CC   -!- Formerly EC 3.4.4.17, EC 3.4.23.6 and EC 3.4.23.8.
PR   PROSITE; PDOC00128;
DR   D4B385, CARP_ARTBC ;  C5FS55, CARP_ARTOC ;  O42630, CARP_ASPFU ;
DR   D4DEN7, CARP_TRIVH ;  P07267, CARP_YEAST ;
//
ID   3.4.23.26
DE   Rhodotorulapepsin.
AN   Rhodotorula aspartic proteinase.
CA   Specificity similar to that of pepsin A. Cleaves Z-Lys-|-Ala-Ala-Ala and
CA   activates trypsinogen.
CC   -!- From the imperfect yeast Rhodotorula glutinis.
CC   -!- Somewhat similar enzymes have been isolated from the imperfect yeast-
CC       like organism Cladosporium sp. and the imperfect fungus Paecilomyces
CC       varioti.
CC   -!- Formerly EC 3.4.4.17 and EC 3.4.23.6.
//
ID   3.4.23.27
DE   Transferred entry: 3.4.21.103.
//
ID   3.4.23.28
DE   Acrocylindropepsin.
AN   Acrocylindrium proteinase.
CA   Preference for hydrophobic residue at P1 and P1'. Action on the B chain
CA   of insulin is generally similar to that of pepsin A, but it also cleaves
CA   6-Leu-|-Cys(SO(3)H)-7, 21-Glu-|-Arg-22 and 3-Asn-|-Gln-4, although not
CA   4-Gln-|-His-5.
CC   -!- From the imperfect fungus Acrocylindrium sp.
CC   -!- Has a very low pH optimum on casein of 2.0.
CC   -!- Formerly EC 3.4.4.17, EC 3.4.23.6 and EC 3.4.99.1.
//
ID   3.4.23.29
DE   Polyporopepsin.
AN   Polyporus aspartic proteinase.
CA   Milk clotting activity, broad specificity, but fails to cleave
CA   15-Leu-|-Tyr-16 or 16-Tyr-|-Leu-17 of insulin B chain.
CC   -!- From the basidiomycete Irpex lacteus (also known as Polyporus
CC       tulipiferae).
CC   -!- Belongs to peptidase family A1.
CC   -!- Formerly EC 3.4.4.17.
PR   PROSITE; PDOC00128;
DR   P17576, CARP_IRPLA ;
//
ID   3.4.23.30
DE   Pycnoporopepsin.
AN   Proteinase Ia.
CA   Specificity similar to pepsin A, but narrower, cleaving only three bonds
CA   in the B chain of insulin: 14-Ala-|-Leu-15, 16-Tyr-|-Leu-17,
CA   and 24-Phe-|-Phe-25.
CC   -!- From the basidiomycete Pycnoporus sanguineus, formerly known as
CC       P.coccineus and Trametes sanguinea.
CC   -!- Formerly EC 3.4.4.17 and EC 3.4.23.6.
//
ID   3.4.23.31
DE   Scytalidopepsin A.
AN   Scytalidium aspartic proteinase A.
CA   Hydrolysis of proteins with specificity similar to that of pepsin A,
CA   but also cleaves 7-Cys(SO(3)H)-|-Gly-8 and 17-Leu-|-Val-18 in the B chain
CA   of insulin.
CC   -!- Isolated from the imperfect fungus Scytalidium lignicolum.
CC   -!- Not inhibited by pepstatin-Ac, methyl 2-diazoacetamidohexanoate or
CC       1,2-epoxy-3-(p-nitrophenyl)propane.
CC   -!- A related enzyme from the same organism, proteinase C, is also
CC       insensitive to these inhibitors and has molecular weight 406 kDa.
//
ID   3.4.23.32
DE   Scytalidopepsin B.
AN   Scytalidium aspartic proteinase B.
CA   Hydrolysis of proteins with broad specificity, cleaving 24-Phe-|-Phe-25,
CA   but not 15-Leu-|-Tyr-16 and 25-Phe-|-Tyr-26 in the B chain of insulin.
CC   -!- Isolated from the imperfect fungus Scytalidium lignicolum.
CC   -!- A second endopeptidase from S.lignicolum (see scytalidopepsin A) that
CC       is insensitive to pepstatin and methyl 2-diazoacetamidohexanoate.
CC   -!- 1,2-epoxy-3-(p-nitrophenoxy)propane reacts with Glu-53, which
CC       replaces one of the aspartic residues at the active center.
CC   -!- One of the smallest aspartic endopeptidases active as the monomer,
CC       with molecular weight 22 kDa.
CC   -!- Similarly inhibitor-resistant endopeptidases are found in the
CC       basidiomycetes Lentinus edodes and Ganoderma lucidum, and in
CC       Polyporus tulipiferae (a second endopeptidase distinct from
CC       polyporopepsin), but these are of typical aspartic endopeptidase
CC       size.
CC   -!- Belongs to peptidase family G1.
PR   PROSITE; PDOC00128;
DR   P15369, PRTB_SCYLI ;
//
ID   3.4.23.33
DE   Transferred entry: 3.4.21.101.
//
ID   3.4.23.34
DE   Cathepsin E.
AN   Erythrocyte membrane aspartic proteinase.
AN   Slow-moving proteinase.
CA   Similar to cathepsin D, but slightly broader specificity.
CC   -!- Found in stomach, spleen, erythrocyte membrane; not lysosomal.
CC   -!- Pro-cathepsin E is an 86 kDa disulfide-linked dimer; activation or
CC       reduction produces monomers.
CC   -!- Belongs to peptidase family A1.
PR   PROSITE; PDOC00128;
DR   Q805F3, CATEA_XENLA;  Q805F2, CATEB_XENLA;  P25796, CATE_CAVPO ;
DR   P14091, CATE_HUMAN ;  P70269, CATE_MOUSE ;  P43159, CATE_RABIT ;
DR   Q800A0, CATE_RANCA ;  P16228, CATE_RAT   ;
//
ID   3.4.23.35
DE   Barrierpepsin.
AN   Bar proteinase.
AN   Extracellular 'barrier' protein.
CA   Selective cleavage of 6-Leu-|-Lys-7 bond in the pheromone alpha-mating
CA   factor.
CC   -!- Belongs to peptidase family A1.
PR   PROSITE; PDOC00128;
DR   P12630, BAR1_YEAST ;
//
ID   3.4.23.36
DE   Signal peptidase II.
AN   Bacterial leader peptidase I.
AN   Lipoprotein signal peptidase.
AN   Premurein-leader peptidase.
AN   Prolipoprotein-signal peptidase.
AN   SPase II.
CA   Release of signal peptides from bacterial membrane prolipoproteins.
CA   Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is
CA   hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala)
CA   have small, neutral side chains.
CC   -!- Inhibited by pepstatin and the antibiotic globomycin.
CC   -!- Belongs to peptidase family A8.
CC   -!- Formerly EC 3.4.99.35.
PR   PROSITE; PDOC00669;
DR   B0C3E3, LSPA_ACAM1 ;  Q6FG03, LSPA_ACIAD ;  B7H305, LSPA_ACIB3 ;
DR   B0VMM0, LSPA_ACIBS ;  A3M0S2, LSPA_ACIBT ;  A6VQH9, LSPA_ACTSZ ;
DR   A0KG40, LSPA_AERHH ;  B9JZH6, LSPA_AGRVS ;  B4RVP1, LSPA_ALTMD ;
DR   B3EU56, LSPA_AMOA5 ;  A7H688, LSPA_ANADF ;  B9KGU3, LSPA_ANAMF ;
DR   Q5P9U0, LSPA_ANAMM ;  Q2GIV1, LSPA_ANAPZ ;  B9MS17, LSPA_ANATD ;
DR   Q3MA96, LSPA_ANAVT ;  B7GFB0, LSPA_ANOFW ;  O67692, LSPA_AQUAE ;
DR   A1K4R6, LSPA_AZOSB ;  A7Z4G5, LSPA_BACA2 ;  C3P663, LSPA_BACAA ;
DR   C3L732, LSPA_BACAC ;  Q81WE6, LSPA_BACAN ;  B7JJY0, LSPA_BACC0 ;
DR   Q732H6, LSPA_BACC1 ;  B7IUQ3, LSPA_BACC2 ;  C1EPQ7, LSPA_BACC3 ;
DR   B7H6M9, LSPA_BACC4 ;  B7HLM7, LSPA_BACC7 ;  A7GRL8, LSPA_BACCN ;
DR   B9IVX0, LSPA_BACCQ ;  Q636D3, LSPA_BACCZ ;  Q9K9V2, LSPA_BACHD ;
DR   Q6HES1, LSPA_BACHK ;  A8FD10, LSPA_BACP2 ;  Q5WFI5, LSPA_BACSK ;
DR   Q45479, LSPA_BACSU ;  A9VTD3, LSPA_BACWK ;  A1UUG9, LSPA_BARBK ;
DR   Q6G5A2, LSPA_BARHE ;  Q6G1A8, LSPA_BARQU ;  A9IL10, LSPA_BART1 ;
DR   B2II67, LSPA_BEII9 ;  A1A2I0, LSPA_BIFAA ;  B3DQ87, LSPA_BIFLD ;
DR   Q8G7W3, LSPA_BIFLO ;  B7GQ27, LSPA_BIFLS ;  Q7VQK9, LSPA_BLOFL ;
DR   Q493S2, LSPA_BLOPB ;  Q0SN37, LSPA_BORAP ;  O51425, LSPA_BORBU ;
DR   B7J235, LSPA_BORBZ ;  B5RM28, LSPA_BORDL ;  Q661F0, LSPA_BORGA ;
DR   B2S0H3, LSPA_BORHD ;  B5RRS4, LSPA_BORRA ;  A1QZQ6, LSPA_BORT9 ;
DR   C0ZG49, LSPA_BREBN ;  B2S8E3, LSPA_BRUA1 ;  Q2YNY8, LSPA_BRUA2 ;
DR   Q57FM7, LSPA_BRUAB ;  A9M794, LSPA_BRUC2 ;  C0RGK4, LSPA_BRUMB ;
DR   Q8YES8, LSPA_BRUME ;  A5VN85, LSPA_BRUO2 ;  B0CIQ7, LSPA_BRUSI ;
DR   Q8G308, LSPA_BRUSU ;  B8D8U9, LSPA_BUCA5 ;  P57248, LSPA_BUCAI ;
DR   Q8K9Z3, LSPA_BUCAP ;  B8D753, LSPA_BUCAT ;  Q89AV0, LSPA_BUCBP ;
DR   B1YVA5, LSPA_BURA4 ;  Q1BUA0, LSPA_BURCA ;  B1JXC4, LSPA_BURCC ;
DR   A0K9T6, LSPA_BURCH ;  B4E8Z8, LSPA_BURCJ ;  Q0BCK7, LSPA_BURCM ;
DR   A9AGN5, LSPA_BURM1 ;  A3MN08, LSPA_BURM7 ;  A2S502, LSPA_BURM9 ;
DR   Q62HL3, LSPA_BURMA ;  A1V6V3, LSPA_BURMS ;  A3NSD0, LSPA_BURP0 ;
DR   Q3JV70, LSPA_BURP1 ;  A3N6P6, LSPA_BURP6 ;  B2JDY8, LSPA_BURP8 ;
DR   B2T6I8, LSPA_BURPP ;  Q63WI4, LSPA_BURPS ;  Q39DM7, LSPA_BURS3 ;
DR   Q2T0H4, LSPA_BURTA ;  A4JH33, LSPA_BURVG ;  A8FKE9, LSPA_CAMJ8 ;
DR   A7H513, LSPA_CAMJD ;  Q0PBE9, LSPA_CAMJE ;  A1VY81, LSPA_CAMJJ ;
DR   Q5HWA6, LSPA_CAMJR ;  Q9AAA6, LSPA_CAUCR ;  B3PE13, LSPA_CELJU ;
DR   Q5L6Q8, LSPA_CHLAB ;  Q3AQW9, LSPA_CHLCH ;  Q824E2, LSPA_CHLCV ;
DR   Q253G9, LSPA_CHLFF ;  B3EEM7, LSPA_CHLL2 ;  Q9PJY8, LSPA_CHLMU ;
DR   B3QQ42, LSPA_CHLP8 ;  B3ELA5, LSPA_CHLPB ;  A1BED5, LSPA_CHLPD ;
DR   Q9Z817, LSPA_CHLPN ;  B0B7X8, LSPA_CHLT2 ;  Q3KLU5, LSPA_CHLTA ;
DR   B0BC43, LSPA_CHLTB ;  Q8KBH7, LSPA_CHLTE ;  O84413, LSPA_CHLTR ;
DR   Q7NS58, LSPA_CHRVO ;  A8ALT5, LSPA_CITK8 ;  Q97H98, LSPA_CLOAB ;
DR   Q182T8, LSPA_CLOD6 ;  A0Q072, LSPA_CLONN ;  Q894D4, LSPA_CLOTE ;
DR   A3DDW4, LSPA_CLOTH ;  A9KEI7, LSPA_COXBN ;  A9NBM6, LSPA_COXBR ;
DR   Q83EC8, LSPA_COXBU ;  Q0K799, LSPA_CUPNH ;  Q46XM6, LSPA_CUPPJ ;
DR   B3R6E9, LSPA_CUPTR ;  B8HXG1, LSPA_CYAP4 ;  B7KFK1, LSPA_CYAP7 ;
DR   Q3Z6R4, LSPA_DEHE1 ;  A5FPV7, LSPA_DEHSB ;  Q3ZYT1, LSPA_DEHSC ;
DR   Q9RRU7, LSPA_DEIRA ;  C6BV90, LSPA_DESAD ;  C0QGT5, LSPA_DESAH ;
DR   Q30ZF6, LSPA_DESDG ;  B8FT17, LSPA_DESHD ;  Q24TI7, LSPA_DESHY ;
DR   Q6AK46, LSPA_DESPS ;  Q72AR4, LSPA_DESVH ;  A1VCU2, LSPA_DESVV ;
DR   A5EWT1, LSPA_DICNV ;  A7ZHB6, LSPA_ECO24 ;  B7UI72, LSPA_ECO27 ;
DR   B7MAE7, LSPA_ECO45 ;  B7L4E9, LSPA_ECO55 ;  Q8XA48, LSPA_ECO57 ;
DR   B5YYB9, LSPA_ECO5E ;  B7NHD1, LSPA_ECO7I ;  B7MNN2, LSPA_ECO81 ;
DR   B7M0C3, LSPA_ECO8A ;  C4ZPV3, LSPA_ECOBW ;  B1XBF2, LSPA_ECODH ;
DR   A7ZVX5, LSPA_ECOHS ;  A1A775, LSPA_ECOK1 ;  Q0TLW4, LSPA_ECOL5 ;
DR   Q8FLB6, LSPA_ECOL6 ;  B1IRE8, LSPA_ECOLC ;  P00804, LSPA_ECOLI ;
DR   B7N7Q1, LSPA_ECOLU ;  B6HZ22, LSPA_ECOSE ;  B1LFV7, LSPA_ECOSM ;
DR   Q1RGH5, LSPA_ECOUT ;  A4W6E2, LSPA_ENT38 ;  P13514, LSPA_ENTAE ;
DR   Q834D8, LSPA_ENTFA ;  A7MIM2, LSPA_ENTS8 ;  B2VH02, LSPA_ERWT9 ;
DR   B7LVN3, LSPA_ESCF3 ;  Q14HT3, LSPA_FRAT1 ;  Q2A4Z5, LSPA_FRATH ;
DR   B2SF87, LSPA_FRATM ;  A0Q528, LSPA_FRATN ;  Q0BNB6, LSPA_FRATO ;
DR   Q5NGD1, LSPA_FRATT ;  Q8RH46, LSPA_FUSNN ;  Q5L0V0, LSPA_GEOKA ;
DR   Q39YS9, LSPA_GEOMG ;  Q747Y0, LSPA_GEOSL ;  A4IM26, LSPA_GEOTN ;
DR   Q7NPI3, LSPA_GLOVI ;  Q7VPK5, LSPA_HAEDU ;  Q4QLQ6, LSPA_HAEI8 ;
DR   A5UID8, LSPA_HAEIG ;  P44975, LSPA_HAEIN ;  Q0I1V9, LSPA_HAES1 ;
DR   B0UV09, LSPA_HAES2 ;  B8CWL9, LSPA_HALOH ;  Q17VS8, LSPA_HELAH ;
DR   B6JPH7, LSPA_HELP2 ;  Q1CV80, LSPA_HELPH ;  Q9ZMZ3, LSPA_HELPJ ;
DR   B2UW72, LSPA_HELPS ;  P25178, LSPA_HELPY ;  A6SW70, LSPA_JANMA ;
DR   B5Y234, LSPA_KLEP3 ;  A6T4G1, LSPA_KLEP7 ;  Q043I1, LSPA_LACGA ;
DR   Q74JC2, LSPA_LACJO ;  Q9CGU5, LSPA_LACLA ;  Q48729, LSPA_LACLM ;
DR   Q02ZK6, LSPA_LACLS ;  Q88W75, LSPA_LACPL ;  Q1WTX7, LSPA_LACS1 ;
DR   Q38X31, LSPA_LACSS ;  Q6AE72, LSPA_LEIXX ;  B0S977, LSPA_LEPBA ;
DR   Q04QT4, LSPA_LEPBJ ;  Q053U5, LSPA_LEPBL ;  B0SRR1, LSPA_LEPBP ;
DR   Q72PS8, LSPA_LEPIC ;  Q8F6H0, LSPA_LEPIN ;  Q92AG4, LSPA_LISIN ;
DR   C1KWE3, LSPA_LISMC ;  Q71YH2, LSPA_LISMF ;  B8DDQ9, LSPA_LISMH ;
DR   Q8Y656, LSPA_LISMO ;  A0AJU9, LSPA_LISW6 ;  A9W565, LSPA_METEP ;
DR   B8IB41, LSPA_METNO ;  A2SKB1, LSPA_METPP ;  B1LSB3, LSPA_METRJ ;
DR   B0UDF9, LSPA_METS4 ;  B8ETD6, LSPA_METSB ;  B0JFT3, LSPA_MICAN ;
DR   Q2RK54, LSPA_MOOTA ;  A0QHM5, LSPA_MYCA1 ;  P65263, LSPA_MYCBO ;
DR   A1KIW9, LSPA_MYCBP ;  Q7NBQ3, LSPA_MYCGA ;  Q49401, LSPA_MYCGE ;
DR   B8ZR76, LSPA_MYCLB ;  Q9X7E7, LSPA_MYCLE ;  Q8EWS0, LSPA_MYCPE ;
DR   P75484, LSPA_MYCPN ;  P65262, LSPA_MYCTU ;  B2A2J1, LSPA_NATTJ ;
DR   Q5FAF3, LSPA_NEIG1 ;  A9M1J8, LSPA_NEIM0 ;  P65264, LSPA_NEIMA ;
DR   P65265, LSPA_NEIMB ;  A1KS63, LSPA_NEIMF ;  Q1QIP9, LSPA_NITHX ;
DR   B2IU55, LSPA_NOSP7 ;  Q8YNI8, LSPA_NOSS1 ;  Q8ER40, LSPA_OCEIH ;
DR   A5CFG7, LSPA_ORITB ;  B3CS08, LSPA_ORITI ;  P57959, LSPA_PASMU ;
DR   Q3A1R4, LSPA_PELCD ;  Q3B5L1, LSPA_PELLD ;  B4SD15, LSPA_PELPB ;
DR   A5D178, LSPA_PELTS ;  Q4FPB0, LSPA_PELUB ;  Q7N8X1, LSPA_PHOLL ;
DR   B1XW26, LSPA_POLNS ;  Q125P4, LSPA_POLSJ ;  B2RI39, LSPA_PORG3 ;
DR   Q7MUD1, LSPA_PORGI ;  A4SDK1, LSPA_PROVI ;  Q15R05, LSPA_PSEA6 ;
DR   A6VBU6, LSPA_PSEA7 ;  Q02GB8, LSPA_PSEAB ;  Q9HVM5, LSPA_PSEAE ;
DR   Q4K5U5, LSPA_PSEF5 ;  P17942, LSPA_PSEFL ;  Q3IEA1, LSPA_PSEHT ;
DR   A4XQV6, LSPA_PSEMY ;  Q3K6L6, LSPA_PSEPF ;  Q88Q91, LSPA_PSEPK ;
DR   Q889E3, LSPA_PSESM ;  A1SZP2, LSPA_PSYIN ;  Q8XWL5, LSPA_RALSO ;
DR   Q98GR1, LSPA_RHILO ;  Q92SJ3, LSPA_RHIME ;  C3MEK8, LSPA_RHISN ;
DR   Q7UF32, LSPA_RHOBA ;  Q6N1M9, LSPA_RHOPA ;  B3Q7Z4, LSPA_RHOPT ;
DR   Q0SHT6, LSPA_RHOSR ;  C3PND1, LSPA_RICAE ;  A8GNC3, LSPA_RICAH ;
DR   A8GVJ0, LSPA_RICB8 ;  Q1RI47, LSPA_RICBR ;  A8EZ20, LSPA_RICCK ;
DR   Q92I62, LSPA_RICCN ;  Q4ULU0, LSPA_RICFE ;  Q9ZDC4, LSPA_RICPR ;
DR   Q68WX1, LSPA_RICTY ;  B5F725, LSPA_SALA4 ;  A9MR45, LSPA_SALAR ;
DR   Q57TL4, LSPA_SALCH ;  B5FHE1, LSPA_SALDC ;  B5R1N7, LSPA_SALEP ;
DR   B5RG82, LSPA_SALG2 ;  B4TIE6, LSPA_SALHS ;  B4T6H3, LSPA_SALNS ;
DR   Q5PDL8, LSPA_SALPA ;  C0Q4I6, LSPA_SALPC ;  B5BLL1, LSPA_SALPK ;
DR   B4TWN7, LSPA_SALSV ;  Q8Z9N1, LSPA_SALTI ;  Q8ZRY9, LSPA_SALTY ;
DR   O52213, LSPA_SERMA ;  A8G9L5, LSPA_SERP5 ;  A1S426, LSPA_SHEAM ;
DR   B8EFC6, LSPA_SHEB2 ;  A3D1G6, LSPA_SHEB5 ;  A6WKD5, LSPA_SHEB8 ;
DR   A9L4U8, LSPA_SHEB9 ;  B0TJB0, LSPA_SHEHH ;  A3QBX3, LSPA_SHELP ;
DR   Q8EBI5, LSPA_SHEON ;  A8H1H4, LSPA_SHEPA ;  B8CSC0, LSPA_SHEPW ;
DR   A8FSI3, LSPA_SHESH ;  Q0HFZ0, LSPA_SHESM ;  Q0HS83, LSPA_SHESR ;
DR   B1KIT6, LSPA_SHEWM ;  B2U246, LSPA_SHIB3 ;  Q326J6, LSPA_SHIBS ;
DR   Q32K70, LSPA_SHIDS ;  Q0T8G7, LSPA_SHIF8 ;  Q83MH1, LSPA_SHIFL ;
DR   Q3Z5Y3, LSPA_SHISS ;  Q2NVY5, LSPA_SODGM ;  Q01VL4, LSPA_SOLUE ;
DR   Q1GQK7, LSPA_SPHAL ;  A5VCW2, LSPA_SPHWW ;  A7X1E3, LSPA_STAA1 ;
DR   A6U115, LSPA_STAA2 ;  Q2FHP2, LSPA_STAA3 ;  Q2FZ79, LSPA_STAA8 ;
DR   A5IS81, LSPA_STAA9 ;  Q2YXH2, LSPA_STAAB ;  Q5HGN6, LSPA_STAAC ;
DR   A6QG97, LSPA_STAAE ;  P65266, LSPA_STAAM ;  P65267, LSPA_STAAN ;
DR   Q6GHN9, LSPA_STAAR ;  Q6GA17, LSPA_STAAS ;  A8Z3N3, LSPA_STAAT ;
DR   P31024, LSPA_STAAU ;  P65268, LSPA_STAAW ;  Q59835, LSPA_STACT ;
DR   Q5HPZ5, LSPA_STAEQ ;  Q8CPK0, LSPA_STAES ;  Q4L5P8, LSPA_STAHJ ;
DR   Q3K0E6, LSPA_STRA1 ;  Q8E4G5, LSPA_STRA3 ;  Q8DYV7, LSPA_STRA5 ;
DR   Q82AC7, LSPA_STRAW ;  Q9S2X7, LSPA_STRCO ;  B1W0K0, LSPA_STRGG ;
DR   Q8DUQ0, LSPA_STRMU ;  Q9A0D2, LSPA_STRP1 ;  P0DC20, LSPA_STRP3 ;
DR   Q5XCS3, LSPA_STRP6 ;  Q8P1G4, LSPA_STRP8 ;  Q1JCF3, LSPA_STRPB ;
DR   Q1JMD2, LSPA_STRPC ;  Q1JHH8, LSPA_STRPD ;  Q1J798, LSPA_STRPF ;
DR   A2RF66, LSPA_STRPG ;  Q48U75, LSPA_STRPM ;  P0DC21, LSPA_STRPQ ;
DR   Q8DQ64, LSPA_STRR6 ;  Q5M0X5, LSPA_STRT1 ;  Q5M5G2, LSPA_STRT2 ;
DR   Q03LU4, LSPA_STRTD ;  Q30NW9, LSPA_SULDN ;  A6Q6B7, LSPA_SULNB ;
DR   B2V758, LSPA_SULSY ;  Q67Q16, LSPA_SYMTH ;  Q2LTG5, LSPA_SYNAS ;
DR   Q7U7A6, LSPA_SYNPX ;  A5GTI3, LSPA_SYNR3 ;  Q0AXF8, LSPA_SYNWW ;
DR   P73540, LSPA_SYNY3 ;  C5BQX3, LSPA_TERTT ;  Q8DGA3, LSPA_THEEB ;
DR   Q8R9R0, LSPA_THETN ;  B5YJT2, LSPA_THEYD ;  Q31ID1, LSPA_THICR ;
DR   C4LD11, LSPA_TOLAT ;  Q73JG0, LSPA_TREDE ;  O83943, LSPA_TREPA ;
DR   Q83I41, LSPA_TROW8 ;  Q83G22, LSPA_TROWT ;  A5F8Z4, LSPA_VIBC3 ;
DR   Q9KU46, LSPA_VIBCH ;  C3LST8, LSPA_VIBCM ;  A7MTD7, LSPA_VIBHB ;
DR   Q87S89, LSPA_VIBPA ;  Q8DES8, LSPA_VIBVU ;  Q7MNM7, LSPA_VIBVY ;
DR   Q8D2R1, LSPA_WIGBR ;  Q7M9M1, LSPA_WOLSU ;  Q8PN18, LSPA_XANAC ;
DR   Q3BW41, LSPA_XANC5 ;  Q4US41, LSPA_XANC8 ;  Q8PBG5, LSPA_XANCP ;
DR   Q2P5A9, LSPA_XANOM ;  B2STC5, LSPA_XANOP ;  Q5H2E0, LSPA_XANOR ;
DR   B2I6V1, LSPA_XYLF2 ;  Q9PAS8, LSPA_XYLFA ;  B0U3Q8, LSPA_XYLFM ;
DR   Q87BL6, LSPA_XYLFT ;  A1JJE2, LSPA_YERE8 ;  A7FMD6, LSPA_YERP3 ;
DR   Q1C0J2, LSPA_YERPA ;  B2K3M7, LSPA_YERPB ;  Q8ZIL9, LSPA_YERPE ;
DR   A9R007, LSPA_YERPG ;  Q1CMV0, LSPA_YERPN ;  A4TQF2, LSPA_YERPP ;
DR   Q66ES3, LSPA_YERPS ;  B1JKZ7, LSPA_YERPY ;
//
ID   3.4.23.37
DE   Transferred entry: 3.4.21.100.
//
ID   3.4.23.38
DE   Plasmepsin I.
AN   Aspartic hemoglobinase I.
AN   PfAPG.
CA   Hydrolysis of the 33-Phe-|-Leu-34 bond in the alpha-chain of hemoglobin,
CA   leading to denaturation of molecule.
CC   -!- Inhibited by pepstatin.
CC   -!- Belongs to peptidase family A1.
PR   PROSITE; PDOC00128;
DR   Q7KQM4, PLM1_PLAF7 ;  P39898, PLM1_PLAFA ;
//
ID   3.4.23.39
DE   Plasmepsin II.
AN   Aspartic hemoglobinase II.
AN   PfAPD.
CA   Hydrolysis of the bonds linking certain hydrophobic residues in
CA   hemoglobin or globin. Also cleaves small molecules substrates such as
CA   Ala-Leu-Glu-Arg-Thr-Phe-|-Phe(NO(2))-Ser-Phe-Pro-Thr.
CC   -!- Inhibited by pepstatin.
CC   -!- Belongs to peptidase family A1.
PR   PROSITE; PDOC00128;
DR   P46925, PLM2_PLAFA ;
//
ID   3.4.23.40
DE   Phytepsin.
CA   Prefers hydrophobic residues Phe, Val, Ile, Leu, and Ala at P1 and P1',
CA   but also cleaves -Phe-|-Asp- and -Asp-|-Asp- bonds in 2S albumin from
CA   plant seeds.
CC   -!- Known particularly fron barley grain, but present in other plants
CC       also.
CC   -!- Belongs to peptidase family A1.
PR   PROSITE; PDOC00128;
DR   P42210, ASPR_HORVU ;
//
ID   3.4.23.41
DE   Yapsin 1.
AN   Aspartic proteinase 3.
AN   Yeast aspartic protease 3.
CA   Hydrolyzes various precursor proteins with Arg or Lys in P1, and commonly
CA   Arg or Lys also in P2. The P3 amino acid is usually non-polar,
CA   but otherwise additional basic amino acids are favorable in both non-
CA   prime and prime positions.
CC   -!- Weakly inhibited by pepstatin.
CC   -!- Can partially substitute for kexin in a deficient strain of
CC       Saccharomyces cerevisiae.
CC   -!- The homologous product of the MKC7 gene (S.cerevisiae) has similar
CC       catalytic activity and has been termed yapsin 2.
CC   -!- Belongs to peptidase family A1.
PR   PROSITE; PDOC00128;
DR   P53379, MKC7_YEAST ;  P32329, YPS1_YEAST ;
//
ID   3.4.23.42
DE   Thermopsin.
CA   Specificity similar to pepsin A, prefers bulky hydrophobic side-chains on
CA   either side of the scissible bond.
CC   -!- Isolated from cells and culture medium of the thermophilic archae
CC       Sulfolobus acidocaldarius, optimum digestion at pH 2 and 90 degrees
CC       Celsius, inhibited by pepstatin.
CC   -!- Another thermostable bacterial endopeptidase has been isolated from
CC       Bacillus sp., but this is not inhibited by pepstatin.
CC   -!- Belongs to peptidase family A5.
CC   -!- Formerly EC 3.4.99.43.
DR   P17118, THPS_SULAC ;
//
ID   3.4.23.43
DE   Prepilin peptidase.
CA   Typically cleaves a -Gly-|-Phe- bond to release an N-terminal, basic
CA   peptide of 5-8 residues from type IV prepilin, and then N-methylates the
CA   new N-terminal amino group, the methyl donor being S-adenosyl-L-
CA   methionine.
CC   -!- Many species of bacteria carry pili on their cell surfaces.
CC   -!- These are virulence determinants in pathogenic strains, and are
CC       assembled biosynthetically from type IV prepilin subunits.
CC   -!- Before assembly, the prepilin molecules require proteolytic
CC       processing, which is done by the prepilin peptidase.
CC   -!- Prepilin peptidase and its homologs play a central role not only in
CC       type IV pilus biogenesis but also in transport of macromolecules
CC       across cell membranes.
CC   -!- Although both peptide-bond hydrolysis and N-methylation are catalyzed
CC       by the same molecule, the methylation can be inhibited without
CC       affecting peptidase activity, and it is believed that the enzyme has
CC       two separate catalytic sites.
CC   -!- Belongs to peptidase family A24.
DR   P45794, LEP4_AERHY ;  A2T195, LEP4_AERS4 ;  P0C423, LEP4_AERSA ;
DR   P15378, LEP4_BACSU ;  Q9ZF70, LEP4_BURPS ;  Q46525, LEP4_DICNO ;
DR   P25960, LEP4_ECOLI ;  P31711, LEP4_ERWCH ;  P44620, LEP4_HAEIN ;
DR   P15754, LEP4_KLEPN ;  O68433, LEP4_LEGPN ;  O30387, LEP4_MYXXD ;
DR   P33566, LEP4_NEIGO ;  P31712, LEP4_PECCC ;  P22610, LEP4_PSEAE ;
DR   P36642, LEP4_PSEPU ;  Q9ZEL6, LEP4_PSEST ;  P72640, LEP4_SYNY3 ;
DR   A5F385, LEP4_VIBC3 ;  P0C6D9, LEP4_VIBCH ;  Q56740, LEP4_VIBVU ;
DR   Q56763, LEP4_XANCP ;
//
ID   3.4.23.44
DE   Nodavirus endopeptidase.
AN   Black Beetle virus endopeptidase.
AN   Flock House virus endopeptidase.
CA   Hydrolysis of an asparaginyl bond involved in the maturation of the
CA   structural protein of the virus, typically -Asn-|-Ala- or -Asn-|-Phe-.
CC   -!- A single aspartic residue is critical for activity, and inhibition by
CC       EDTA indicates that a metal ion is also important.
CC   -!- The enzyme is known from several nodaviruses that are pathogens of
CC       insects.
CC   -!- Belongs to peptidase family A6.
DR   P04329, CAPSD_BBV  ;  P12869, CAPSD_BOOLV;  P12870, CAPSD_FHV  ;
DR   P12871, CAPSD_NODAM;  Q9J7Z0, CAPSD_PAV  ;
//
ID   3.4.23.45
DE   Memapsin 1.
AN   ASP1.
AN   BACE2.
AN   Beta-secretase.
AN   Beta-site Alzheimer's amyloid precursor protein cleaving enzyme 2.
AN   Beta-site APP-cleaving enzyme 2.
AN   Down region aspartic protease.
AN   Membrane-associated aspartic protease 1.
CA   Broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-|-Asp-Ala-Glu-
CA   Phe in the Swedish variant of Alzheimer's amyloid precursor protein.
CC   -!- Can cleave beta-amyloid precursor protein to form the amyloidogenic
CC       beta-peptide that is implicated in the pathology of Alzheimer's
CC       disease, but is not significantly expressed in human brain.
CC   -!- Belongs to peptidase family A1.
PR   PROSITE; PDOC00128;
DR   Q9Y5Z0, BACE2_HUMAN;  Q9JL18, BACE2_MOUSE;  Q6IE75, BACE2_RAT  ;
//
ID   3.4.23.46
DE   Memapsin 2.
AN   BACE1.
AN   Beta-secretase.
AN   Beta-site Alzheimer's amyloid precursor protein cleaving enzyme 1.
AN   Beta-site APP-cleaving enzyme 1.
AN   Membrane-associated aspartic protease 2.
CA   Broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-|-Asp-Ala-Glu-
CA   Phe in the Swedish variant of Alzheimer's amyloid precursor protein.
CC   -!- Suggested to be the major 'beta-secretase' responsible for the
CC       cleavage of the beta-amyloid precursor protein to form the
CC       amyloidogenic beta-peptide that is implicated in the pathology of
CC       Alzheimer's disease.
CC   -!- Belongs to peptidase family A1.
PR   PROSITE; PDOC00128;
DR   Q2HJ40, BACE1_BOVIN;  Q1KLR6, BACE1_CAVPO;  P56817, BACE1_HUMAN;
DR   P56818, BACE1_MOUSE;  P56819, BACE1_RAT  ;
//
ID   3.4.23.47
DE   HIV-2 retropepsin.
CA   Endopeptidase for which the P1 residue is preferably hydrophobic.
CC   -!- Responsible for the post-translational processing of the human
CC       immunodeficiency virus polyprotein.
CC   -!- Belongs to peptidase family A2.
PR   PROSITE; PDOC00128;
DR   P18096, POL_HV2BE  ;  P24107, POL_HV2CA  ;  P17757, POL_HV2D1  ;
DR   P15833, POL_HV2D2  ;  Q89928, POL_HV2EH  ;  P18042, POL_HV2G1  ;
DR   Q74120, POL_HV2KR  ;  P05962, POL_HV2NZ  ;  P04584, POL_HV2RO  ;
DR   P12451, POL_HV2SB  ;  P20876, POL_HV2ST  ;  Q76634, POL_HV2UC  ;
//
ID   3.4.23.48
DE   Plasminogen activator Pla.
AN   Coagulase/fibrinolysin.
CA   Converts human Glu-plasminogen to plasmin by cleaving the 560-Arg-|-Val-
CA   561 peptide bond that is also hydrolyzed by the mammalian u-plasminogen
CA   activator and t-plasminogen activator. Also cleaves arginyl bonds in
CA   other proteins.
CC   -!- From the bacterium Yersinia pestis that causes plague.
CC   -!- Belongs to peptidase family A26.
DR   P17811, COLY_YERPE ;
//
ID   3.4.23.49
DE   Omptin.
AN   Outer membrane protein 3B.
AN   Protease A.
AN   Protease VII.
CA   Has a virtual requirement for Arg in the P1 position and a slightly less
CA   stringent preference for this residue in the P1' position, which can also
CA   contain Lys, Gly or Val.
CC   -!- Shows a preference for cleavage between consecutive basic amino
CC       acids, but is capable of cleavage when P1' is a non-basic residue.
CC   -!- Belongs to peptidase family A26.
CC   -!- Formerly EC 3.4.21.87.
PR   PROSITE; PDOC00657;
DR   P58603, OMPT_ECO57 ;  P09169, OMPT_ECOLI ;
//
ID   3.4.23.50
DE   Human endogenous retrovirus K endopeptidase.
AN   HERV K10 endopeptidase.
AN   HERV K10 retropepsin.
AN   Human endogenous retrovirus K10 endopeptidase.
AN   Human endogenous retrovirus K113 protease.
AN   Human retrovirus K10 retropepsin.
CA   Processing at the authentic HIV-1 PR recognition site and release of the
CA   mature p17 matrix and the p24 capsid protein, as a result of the cleavage
CA   of the -SQNY-|-PIVQ- cleavage site.
CC   -!- Belongs to peptidase family A2.
PR   PROSITE; PDOC00128;
DR   P63128, POK4_HUMAN ;  P10265, VPK10_HUMAN;  P63129, VPK11_HUMAN;
DR   P63131, VPK12_HUMAN;  P63125, VPK17_HUMAN;  P63119, VPK1_HUMAN ;
DR   Q9Y6I0, VPK2_HUMAN ;  P63120, VPK3_HUMAN ;  P63127, VPK4_HUMAN ;
DR   P63121, VPK5_HUMAN ;  P63122, VPK6_HUMAN ;  P63123, VPK7_HUMAN ;
DR   P63124, VPK9_HUMAN ;
//
ID   3.4.23.51
DE   HycI peptidase.
CA   This enzyme specifically removes a 32-amino acid peptide from the
CA   C-terminus of the precursor of the large subunit of E.coli hydrogenase 3
CA   by cleavage at the C-terminal side of Arg(537).
CC   -!- The reaction requires nickel to be bound to the precursor of the
CC       large subunit of hydrogenase 3.
CC   -!- The endopeptidase uses the metal in the large subunit of [NiFe]-
CC       hydrogenases as a recognition motif.
CC   -!- Belongs to peptidase family A31.
DR   P0AEW0, HYCI_ECO57 ;  P0AEV9, HYCI_ECOLI ;
//
ID   3.4.24.1
DE   Atrolysin A.
AN   Crotalus atrox alpha-proteinase.
AN   Crotalus atrox metalloproteinase.
AN   Hemorrhagic toxin a.
CA   Cleavage of 3-Asn-|-Gln-4, 5-His-|-Leu-6, 10-His-|-Leu-11, 14-Ala-|-Leu-
CA   15 and 16-Tyr-|-Leu-17 in insulin B chain; removes C-terminal Leu from
CA   small peptides.
CF   Zinc.
CC   -!- A hemorrhagic endopeptidase of 68 kDa, one of six hemorrhagic toxins
CC       in the venom of the western diamondback rattlesnake.
CC   -!- The 60 kDa hemorrhagic toxin 1 of Crotalus ruber ruber shows
CC       identical specificity.
CC   -!- Belongs to peptidase family M12B.
PR   PROSITE; PDOC00129;
DR   Q92043, VMATA_CROAT;
//
ID   3.4.24.2
DE   Deleted entry.
//
ID   3.4.24.3
DE   Microbial collagenase.
AN   Clostridiopeptidase A.
AN   Clostridium histolyticum collagenase.
AN   Collagenase A.
AN   Collagenase I.
CA   Digestion of native collagen in the triple helical region at Xaa-|-Gly
CA   bonds. With synthetic peptides, a preference is shown for Gly at P3 and
CA   P1'; Pro and Ala at P2 and P2'; and hydroxyproline, Ala or Arg at P3'.
CF   Zinc.
CC   -!- Six species of metalloendopeptidase acting on native collagen can be
CC       isolated from the medium of Clostridium histolyticum.
CC   -!- Class I has forms alpha (68 kDa), beta (115 kDa) and gamma (79 kDa);
CC       class II has delta (100 kDa), epsilon (110 kDa) and zeta (125 kDa).
CC   -!- The two classes are immunologically crossreactive, but have
CC       significantly different sequences, and different specificities such
CC       that their actions on collagen are complementary.
CC   -!- The enzymes also act as peptidyl-tripeptidases.
CC   -!- Variants of the enzyme have been purified from Bacillus cereus,
CC       Empedobacter collagenolyticum, Pseudomonas marinoglutinosa,
CC       and species of Vibrio, Vibrio B-30 (ATCC 21250) and V.alginolyticus
CC       (previously Achromobacter iophagus).
CC   -!- Also known from Streptomyces sp.
CC   -!- Belongs to peptidase family M9.
CC   -!- Formerly EC 3.4.4.19, EC 3.4.24.8 and EC 3.4.99.5.
DR   P43153, COLA_CLOPE ;  P43154, COLA_VIBAL ;  Q9KRJ0, COLA_VIBCH ;
DR   Q56696, COLA_VIBPA ;  Q8D4Y9, COLA_VIBVU ;
//
ID   3.4.24.4
DE   Transferred entry: 3.4.24.25, 3.4.24.26, 3.4.24.27, 3.4.24.28, 3.4.24.29,
DE   3.4.24.30, 3.4.24.31, 3.4.24.32, 3.4.24.39 and 3.4.24.40.
//
ID   3.4.24.5
DE   Transferred entry: 3.4.22.52, 3.4.22.53 and 3.4.25.1.
//
ID   3.4.24.6
DE   Leucolysin.
AN   Leucostoma neutral proteinase.
CA   Cleavage of 1-Phe-|-Val-2, 5-His-|-Leu-6, 14-Ala-|-Leu-15, 20-Gly-|-Glu-
CA   21, 23-Gly-|-Phe-24 and 24-Phe-|-Phe-25 bonds in insulin B chain as well
CA   as N-blocked dipeptides.
CF   Calcium; Zinc.
CC   -!- From the venom of the western cottonmouth moccasin snake (Agkistrodon
CC       piscivorus leucostoma).
//
ID   3.4.24.7
DE   Interstitial collagenase.
AN   Matrix metalloproteinase 1.
AN   Vertebrate collagenase.
CA   Cleavage of the triple helix of collagen at about three-quarters of the
CA   length of the molecule from the N-terminus, at 775-Gly-|-Ile-776 in the
CA   alpha-1(I) chain. Cleaves synthetic substrates and alpha-macroglobulins
CA   at bonds where P1' is a hydrophobic residue.
CF   Zinc.
CC   -!- The enzyme takes its name from substrates of the interstitial
CC       collagen group - types I, II and III, all of which are cleaved in the
CC       helical domain.
CC   -!- Alpha-macroglobulins are cleaved much more rapidly.
CC   -!- The enzyme is widely distributed in vertebrate animals.
CC   -!- Belongs to peptidase family M10B.
PR   PROSITE; PDOC00129;
DR   P34156, COG4_CHIOP ;  Q9EPL5, MMP1A_MOUSE;  Q9EPL6, MMP1B_MOUSE;
DR   P28053, MMP1_BOVIN ;  Q9XSZ5, MMP1_HORSE ;  P03956, MMP1_HUMAN ;
DR   P21692, MMP1_PIG   ;  P13943, MMP1_RABIT ;  Q11133, MMP1_RANCA ;
DR   P81563, MMP1_RAT   ;
//
ID   3.4.24.8
DE   Transferred entry: 3.4.24.3.
//
ID   3.4.24.9
DE   Deleted entry.
//
ID   3.4.24.10
DE   Deleted entry.
//
ID   3.4.24.11
DE   Neprilysin.
AN   Endopeptidase-2.
AN   Enkephalinase.
AN   Kidney-brush-border neutral proteinase.
AN   Membrane metalloendopeptidase.
AN   Neutral endopeptidase.
CA   Preferential cleavage of polypeptides between hydrophobic residues,
CA   particularly with Phe or Tyr at P1'.
CF   Zinc.
CC   -!- A membrane-bound glycoprotein widely distributed in animal tissues.
CC   -!- Inhibited by phosphoramidon and thiorphan.
CC   -!- Belongs to peptidase family M13.
PR   PROSITE; PDOC00129;
DR   Q495T6, MMEL1_HUMAN;  Q9JLI3, MMEL1_MOUSE;  P0C1T0, MMEL1_RAT  ;
DR   P08473, NEP_HUMAN  ;  Q61391, NEP_MOUSE  ;  P19621, NEP_PIG    ;
DR   Q5RE69, NEP_PONAB  ;  P08049, NEP_RABIT  ;  P07861, NEP_RAT    ;
//
ID   3.4.24.12
DE   Envelysin.
AN   Hatching enzyme.
AN   Sea-urchin-hatching proteinase.
CA   Hydrolysis of proteins of the fertilization envelope and dimethylcasein.
CF   Calcium; Zinc.
CC   -!- Dissolves fertilization envelope in embryos of sea urchin.
CC   -!- Belongs to peptidase family M10B.
PR   PROSITE; PDOC00129;
DR   P91953, HE_HEMPU   ;  P22757, HE_PARLI   ;
//
ID   3.4.24.13
DE   IgA-specific metalloendopeptidase.
AN   IgA protease.
AN   Immunoglobulin A1 proteinase.
CA   Cleavage of Pro-|-Thr bond in the hinge region of the heavy chain of
CA   human IgA.
CF   Zinc.
CC   -!- Found in several pathogenic species of Streptococcus such as
CC       S.sanguis and S.pneumoniae.
CC   -!- There is also an IgA-specific prolyl endopeptidase of serine-type
CC       (see EC 3.4.21.72).
CC   -!- Belongs to peptidase family M26.
DR   Q97QP7, IGA1A_STRPN;  Q54875, IGA1B_STRPN;  Q59947, IGA1_STRR6 ;
DR   Q59986, IGA1_STRSA ;
//
ID   3.4.24.14
DE   Procollagen N-endopeptidase.
AN   Procollagen N-proteinase.
CA   Cleaves the N-propeptide of collagen chain alpha-1(I) at Pro-|-Gln and of
CA   alpha-1(II) and alpha-2(I) at Ala-|-Gln.
CF   Zinc.
CC   -!- Removes N-terminal propeptides of type I and II collagens prior to
CC       fibril assembly.
CC   -!- Does not cleave type III procollagen.
CC   -!- Belongs to peptidase family M12.
PR   PROSITE; PDOC00129;
DR   P79331, ATS2_BOVIN ;  O95450, ATS2_HUMAN ;  Q8C9W3, ATS2_MOUSE ;
//
ID   3.4.24.15
DE   Thimet oligopeptidase.
AN   Endo-oligopeptidase A.
AN   Endopeptidase 24.15.
AN   Pz-peptidase.
AN   Soluble metalloendopeptidase.
CA   Preferential cleavage of bonds with hydrophobic residues at P1, P2 and
CA   P3' and a small residue at P1' in substrates of 5 to 15 residues.
CF   Zinc.
CC   -!- Thiol compounds activate at low concentrations.
CC   -!- Belongs to peptidase family M3.
CC   -!- Formerly EC 3.4.22.19 and EC 3.4.99.31.
PR   PROSITE; PDOC00129;
DR   Q1JPJ8, THOP1_BOVIN;  P52888, THOP1_HUMAN;  Q8C1A5, THOP1_MOUSE;
DR   P47788, THOP1_PIG  ;  P24155, THOP1_RAT  ;
//
ID   3.4.24.16
DE   Neurolysin.
AN   Neurotensin endopeptidase.
CA   Preferential cleavage in neurotensin: 10-Pro-|-Tyr-11.
CF   Zinc.
CC   -!- No absolute requirement for a prolyl bond; the enzyme acts on some
CC       peptides, such as dynorphin 1-8, that do not contain proline,
CC       and does not act on some others that do.
CC   -!- Belongs to peptidase family M3.
PR   PROSITE; PDOC00129;
DR   A2VDQ5, NEUL_BOVIN ;  Q9BYT8, NEUL_HUMAN ;  Q91YP2, NEUL_MOUSE ;
DR   Q02038, NEUL_PIG   ;  Q5R9V6, NEUL_PONAB ;  P42675, NEUL_RABIT ;
DR   P42676, NEUL_RAT   ;
//
ID   3.4.24.17
DE   Stromelysin 1.
AN   Matrix metalloproteinase 3.
AN   Proteoglycanase.
AN   Transin.
CA   Preferential cleavage where P1', P2' and P3' are hydrophobic residues.
CF   Calcium; Zinc.
CC   -!- Extracellular endopeptidase of vertebrate tissues.
CC   -!- Degradation of proteoglycans, fibronectin, collagen type III, IV,
CC       V and IX and activates procollagenase.
CC   -!- Belongs to peptidase family M10B.
PR   PROSITE; PDOC00129;
DR   Q6Y4Q5, MMP3_CANFA ;  Q28397, MMP3_HORSE ;  P08254, MMP3_HUMAN ;
DR   P28862, MMP3_MOUSE ;  P28863, MMP3_RABIT ;  P03957, MMP3_RAT   ;
//
ID   3.4.24.18
DE   Meprin A.
AN   Endopeptidase-2.
CA   Hydrolysis of protein and peptide substrates preferentially on carboxyl
CA   side of hydrophobic residues.
CF   Zinc.
CC   -!- A membrane-bound metalloendopeptidase of rat and mouse kidney and
CC       intestinal brush borders, and salivary ducts.
CC   -!- Differences from EC 3.4.24.11 include insensitivity to phosphoramidon
CC       and thiorphan.
CC   -!- PABA-peptide hydrolase is a very similar enzyme found in human
CC       intestinal microvilli.
CC   -!- Belongs to peptidase family M12A.
PR   PROSITE; PDOC00129;
DR   Q16819, MEP1A_HUMAN;  P28825, MEP1A_MOUSE;  Q64230, MEP1A_RAT  ;
//
ID   3.4.24.19
DE   Procollagen C-endopeptidase.
CA   Cleavage of the C-terminal propeptide at Ala-|-Asp in type I and II
CA   procollagens and at Arg-|-Asp in type III.
CF   Zinc.
CC   -!- The activity is increased by calcium and by an enhancer glycoprotein.
DR   P13497, BMP1_HUMAN ;  P98063, BMP1_MOUSE ;
//
ID   3.4.24.20
DE   Peptidyl-Lys metalloendopeptidase.
AN   Armillaria mellea neutral proteinase.
CA   Preferential cleavage in proteins: -Xaa-|-Lys- (in which Xaa may be Pro).
CC   -!- From the honey fungus Armillaria mellea.
CC   -!- A similar specificity is shown by Myxobacter sp. AL-1 proteinase II
CC       (endoproteinase Lys-C).
CC   -!- Formerly EC 3.4.99.30 and EC 3.4.99.32.
DR   Q9Y7F7, PLMP_ARMME ;  P81054, PLMP_GRIFR ;  P81055, PLMP_PLEOS ;
//
ID   3.4.24.21
DE   Astacin.
AN   Astacus proteinase.
AN   Crayfish small-molecule proteinase.
CA   Hydrolysis of peptide bonds in substrates containing five or more amino
CA   acids, preferentially with Ala in P1', and Pro in P2'.
CF   Zinc.
CC   -!- A digestive endopeptidase from the cardia of the crayfish Astacus
CC       fluviatilis.
CC   -!- Belongs to peptidase family M12A.
CC   -!- Formerly EC 3.4.99.6.
PR   PROSITE; PDOC00129;
DR   P07584, ASTA_ASTFL ;  Q21388, NAS10_CAEEL;  Q21432, NAS11_CAEEL;
DR   Q9XTD6, NAS12_CAEEL;  Q20191, NAS13_CAEEL;  Q19269, NAS14_CAEEL;
DR   P55115, NAS15_CAEEL;  Q21180, NAS16_CAEEL;  Q21178, NAS17_CAEEL;
DR   Q21179, NAS18_CAEEL;  Q21181, NAS19_CAEEL;  O62243, NAS1_CAEEL ;
DR   Q22396, NAS20_CAEEL;  Q22398, NAS22_CAEEL;  Q7Z0M7, NAS23_CAEEL;
DR   Q93542, NAS24_CAEEL;  Q20459, NAS25_CAEEL;  Q22710, NAS26_CAEEL;
DR   O17264, NAS27_CAEEL;  P98061, NAS28_CAEEL;  Q20958, NAS29_CAEEL;
DR   Q9N5R0, NAS2_CAEEL ;  Q9N2V2, NAS30_CAEEL;  Q7JLI1, NAS31_CAEEL;
DR   O16977, NAS32_CAEEL;  P55114, NAS33_CAEEL;  Q21059, NAS34_CAEEL;
DR   P98060, NAS35_CAEEL;  Q61EX6, NAS36_CAEBR;  Q18206, NAS36_CAEEL;
DR   Q93243, NAS37_CAEEL;  Q20942, NAS38_CAEEL;  Q20176, NAS39_CAEEL;
DR   Q21252, NAS3_CAEEL ;  P55112, NAS4_CAEEL ;  P91828, NAS5_CAEEL ;
DR   Q9U3S9, NAS6_CAEEL ;  P55113, NAS7_CAEEL ;  Q18439, NAS8_CAEEL ;
DR   P91137, NAS9_CAEEL ;
//
ID   3.4.24.22
DE   Stromelysin 2.
AN   Matrix metalloproteinase 10.
AN   Transin 2.
CA   Similar to stromelysin 1, but action on collagen types III, IV and V is
CA   weak.
CF   Calcium; Zinc.
CC   -!- Digests gelatin types I, III, IV, V, fibronectin and proteoglycan.
CC   -!- Belongs to peptidase family M10B.
PR   PROSITE; PDOC00129;
DR   P09238, MMP10_HUMAN;  O55123, MMP10_MOUSE;  P07152, MMP10_RAT  ;
//
ID   3.4.24.23
DE   Matrilysin.
AN   Matrin.
AN   Matrix metalloproteinase 7.
AN   PUMP-1.
AN   Putative (or punctuated) metalloproteinase-1.
AN   Uterine metalloendopeptidase.
CA   Cleavage of 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 in B chain of insulin. No
CA   action on collagen types I, II, IV, V. Cleaves gelatin chain alpha-2(I) >
CA   alpha-1(I).
CF   Calcium; Zinc.
CC   -!- Similar in specificity to stromelysin, but more active on azocoll.
CC   -!- Belongs to peptidase family M10B.
PR   PROSITE; PDOC00129;
DR   P55032, MMP7_FELCA ;  P09237, MMP7_HUMAN ;  Q10738, MMP7_MOUSE ;
DR   P50280, MMP7_RAT   ;
//
ID   3.4.24.24
DE   Gelatinase A.
AN   72-kDa gelatinase.
AN   Matrix metalloproteinase 2.
AN   Type IV collagenase.
CA   Cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the
CA   collagen-like sequence Pro-Gln-Gly-|-Ile-Ala-Gly-Gln.
CF   Calcium; Zinc.
CC   -!- Belongs to peptidase family M10B.
PR   PROSITE; PDOC00129;
DR   Q9GLE5, MMP2_BOVIN ;  Q90611, MMP2_CHICK ;  P08253, MMP2_HUMAN ;
DR   P33434, MMP2_MOUSE ;  P50757, MMP2_RABIT ;  P33436, MMP2_RAT   ;
//
ID   3.4.24.25
DE   Vibriolysin.
AN   Aeromonas proteolytica neutral proteinase.
AN   Aeromonolysin.
CA   Preferential cleavage of bonds with bulky hydrophobic groups in P2 and
CA   P1'. Phe at P1' is the most favored residue, which distinguished this
CA   enzyme from thermolysin.
CF   Zinc.
CC   -!- Thermostable enzyme from Vibrio proteolyticus (formerly Aeromonas
CC       proteolytica).
CC   -!- Specificity related to, but distinct from, those of the thermolysin
CC       and Bacillus subtilis endopeptidase.
CC   -!- Belongs to peptidase family M4.
CC   -!- Formerly EC 3.4.24.4.
PR   PROSITE; PDOC00129;
DR   Q00971, NPRV_VIBPR ;
//
ID   3.4.24.26
DE   Pseudolysin.
AN   Pseudomonas aeruginosa neutral metalloproteinase.
AN   Pseudomonas elastase.
CA   Hydrolysis of proteins including elastin, collagen types III and IV,
CA   fibronectin and immunoglobulin A, generally with bulky hydrophobic group
CA   at P1'. Insulin B chain cleavage pattern identical to that of
CA   thermolysin, but specificity differs in other respects.
CF   Calcium; Zinc.
CC   -!- Causes tissue damage.
CC   -!- Belongs to peptidase family M4.
CC   -!- Formerly EC 3.4.24.4.
PR   PROSITE; PDOC00129;
DR   P14756, ELAS_PSEAE ;
//
ID   3.4.24.27
DE   Thermolysin.
AN   Bacillus thermoproteolyticus neutral proteinase.
CA   Preferential cleavage: Xaa-|-Leu > Xaa-|-Phe.
CF   Calcium; Zinc.
CC   -!- A thermostable extracellular metalloendopeptidase containing four
CC       calcium ions.
CC   -!- Enzymes that may be species variants of thermolysin are reported from
CC       Micrococcus caseolyticus and Aspergillus oryzae.
CC   -!- Closely related but distinct enzymes are aeromonolysin, pseudolysin,
CC       bacillolysin, aureolysin and mycolysin.
CC   -!- Belongs to peptidase family M4.
CC   -!- Formerly EC 3.4.24.4.
PR   PROSITE; PDOC00129;
DR   Q43880, THER_ALIAC ;  Q59193, THER_BACCL ;  Q59223, THER_BACSO ;
DR   P00800, THER_BACTH ;
//
ID   3.4.24.28
DE   Bacillolysin.
AN   Bacillus metalloendopeptidase.
AN   Bacillus subtilis neutral proteinase.
AN   Megateriopeptidase.
CA   Similar, but not identical, to that of thermolysin.
CF   Calcium; Zinc.
CC   -!- Variants of this enzyme have been found in species of Bacillus
CC       including B.subtilis, B.amyloliquefaciens, B.megaterium,
CC       B.mesentericus, B.cereus and B.stearothermophilus.
CC   -!- Belongs to peptidase family M4.
CC   -!- Formerly EC 3.4.24.4.
PR   PROSITE; PDOC00129;
DR   P06832, NPRE_BACAM ;  P05806, NPRE_BACCE ;  P23384, NPRE_BACCL ;
DR   P68734, NPRE_BACPU ;  P68735, NPRE_BACSA ;  P68736, NPRE_BACSU ;
DR   P43263, NPRE_BREBE ;  P29148, NPRE_PAEPO ;  D5DEH5, NPRM_BACMD ;
DR   P0CH29, NPRM_BACME ;
//
ID   3.4.24.29
DE   Aureolysin.
AN   Staphylococcus aureus neutral proteinase.
CA   Cleavage of insulin B chain with specificity similar to that of
CA   thermolysin, preferring hydrophobic P1' residues. Activates the glutamyl
CA   endopeptidase (EC 3.4.21.19) of Staphylococcus aureus.
CF   Calcium; Zinc.
CC   -!- Earlier confused with staphylokinase.
CC   -!- Belongs to peptidase family M4.
CC   -!- Formerly EC 3.4.24.4 and EC 3.4.99.22.
PR   PROSITE; PDOC00129;
DR   P81177, AURE_STAAU ;
//
ID   3.4.24.30
DE   Coccolysin.
AN   Streptococcus thermophilus intracellular proteinase.
CA   Preferential cleavage: Xaa-|-Leu, Xaa-|-Phe, Xaa-|-Tyr, Xaa-|-Ala.
CF   Zinc.
CC   -!- A 30 kDa endopeptidase found intracellularly in Streptococcus
CC       thermophilus and S.diacetilactis and in the medium of Enterococcus
CC       faecalis.
CC   -!- Belongs to peptidase family M4.
CC   -!- Formerly included in EC 3.4.24.4.
PR   PROSITE; PDOC00129;
DR   Q833V7, GELE_ENTFA ;
//
ID   3.4.24.31
DE   Mycolysin.
AN   Pronase component.
AN   Streptomyces griseus neutral proteinase.
CA   Preferential cleavage of bonds with hydrophobic residues in P1'.
CF   Zinc.
CC   -!- From Streptomyces griseus, S.naraensis, and S.cacaoi.
CC   -!- Specificity similar to that of thermolysin, but much more sensitive
CC       to inhibition by mercaptoacetyl-Phe-Leu.
CC   -!- Belongs to peptidase family M5.
CC   -!- Formerly EC 3.4.24.4.
PR   PROSITE; PDOC00129;
DR   P20910, MYCO_STRCI ;
//
ID   3.4.24.32
DE   Beta-lytic metalloendopeptidase.
AN   Achromopeptidase component.
AN   Myxobacter beta-lytic proteinase.
CA   Cleavage of N-acetylmuramoyl-|-Ala, and of the insulin B chain at
CA   23-Gly-|-Phe-24 > 18-Val-|-Cys(SO(3)H).
CF   Zinc.
CC   -!- From Achromobacter lyticus and Lysobacter enzymogenes.
CC   -!- Digests bacterial cell walls.
CC   -!- Myxobacter sp. AL-1 proteinase I also has characteristics of this
CC       enzyme.
CC   -!- Belongs to peptidase family M23.
CC   -!- Formerly EC 3.4.24.4 and EC 3.4.99.13.
DR   P27458, PRLB_ACHLY ;  P00801, PRLB_LYSEN ;
//
ID   3.4.24.33
DE   Peptidyl-Asp metalloendopeptidase.
AN   Endoproteinase Asp-N.
CA   Cleavage of Xaa-|-Asp, Xaa-|-Glu and Xaa-|-cysteic acid bonds.
CC   -!- A metalloenzyme isolated from Pseudomonas fragi.
CC   -!- Useful in protein sequencing applications because of its limited
CC       specificity.
CC   -!- Belongs to peptidase family M72.
DR   Q9R4J4, ASPN_PSEFR ;  B4SLL0, ASPN_STRM5 ;  B2FQP3, ASPN_STRMK ;
DR   Q8PC00, ASPN_XANCP ;
//
ID   3.4.24.34
DE   Neutrophil collagenase.
AN   Matrix metalloproteinase 8.
CA   Cleavage of interstitial collagens in the triple helical domain. Unlike
CA   EC 3.4.24.7, this enzyme cleaves type III collagen more slowly than type
CA   I.
CF   Calcium; Zinc.
CC   -!- Similar to interstitial collagenase in specificity.
CC   -!- Stored in the specific granules of neutrophil leukocytes.
CC   -!- Belongs to peptidase family M10B.
PR   PROSITE; PDOC00129;
DR   P22894, MMP8_HUMAN ;  O70138, MMP8_MOUSE ;  O88766, MMP8_RAT   ;
//
ID   3.4.24.35
DE   Gelatinase B.
AN   92-kDa gelatinase.
AN   92-kDa type IV collagenase.
AN   Macrophage gelatinase.
AN   Matrix metalloproteinase 9.
AN   Type V collagenase.
CA   Cleavage of gelatin types I and V and collagen types IV and V.
CF   Calcium; Zinc.
CC   -!- Belongs to peptidase family M10B.
PR   PROSITE; PDOC00129;
DR   P52176, MMP9_BOVIN ;  O18733, MMP9_CANFA ;  P14780, MMP9_HUMAN ;
DR   P41245, MMP9_MOUSE ;  P41246, MMP9_RABIT ;  P50282, MMP9_RAT   ;
//
ID   3.4.24.36
DE   Leishmanolysin.
AN   Glycoprotein gp63.
AN   Promastigote surface endopeptidase.
CA   Preference for hydrophobic residues at P1 and P1' and basic residues at
CA   P2' and P3'. A model nonapeptide is cleaved at -Ala-Tyr-|-Leu-Lys-Lys-.
CF   Calcium; Zinc.
CC   -!- A membrane-bound glycoprotein found on the promastigote of various
CC       species of Leishmania protozoans.
CC   -!- Contains consensus sequence for a zinc binding site; Z-Tyr-Leu-NHOH
CC       is a strong inhibitor.
CC   -!- The enzyme can activate its proenzyme by cleavage of the 100-
CC       Val-|-Val-101 bond.
CC   -!- An acidic pH optimum is found with certain protein substrates.
CC   -!- Belongs to peptidase family M8.
PR   PROSITE; PDOC00129;
DR   Q06031, GP63_CRIFA ;  Q27673, GP63_LEIAM ;  P15706, GP63_LEICH ;
DR   P23223, GP63_LEIDO ;  Q00689, GP63_LEIGU ;  P08148, GP63_LEIMA ;
DR   P43150, GP63_LEIME ;  Q8MNZ1, GP63_LEITR ;
//
ID   3.4.24.37
DE   Saccharolysin.
AN   Oligopeptidase yscD.
AN   Proteinase yscD.
AN   Yeast cysteine proteinase D.
CA   Cleavage of Pro-|-Phe and Ala-|-Ala bonds.
CF   Zinc.
CC   -!- Belongs to peptidase family M3.
CC   -!- Formerly EC 3.4.22.22.
PR   PROSITE; PDOC00129;
DR   P25375, PRTD_YEAST ;
//
ID   3.4.24.38
DE   Gametolysin.
AN   Autolysin.
AN   Chlamydomonas cell wall degrading protease.
AN   Gamete lytic enzyme.
AN   Lysin.
CA   Cleavage of the proline- and hydroxyproline-rich proteins of the
CA   Chlamydomonas cell wall; also cleaves azocasein, gelatin and Leu-
CA   Trp-Met-|-Arg-Phe-Ala.
CF   Zinc.
CC   -!- Inhibited by phosphoramidon, but also thiol-dependent.
CC   -!- Belongs to peptidase family M11.
PR   PROSITE; PDOC00129;
DR   P31178, GLE_CHLRE  ;
//
ID   3.4.24.39
DE   Deuterolysin.
AN   Acid metalloproteinase.
AN   Microbial neutral proteinase II.
AN   Penicillium roqueforti protease II.
CA   Preferential cleavage of bonds with hydrophobic residues in P1'; also
CA   3-Asn-|-Gln-4 and 8-Gly-|-Ser-9 bonds in insulin B chain.
CF   Zinc.
CC   -!- Proteolytic activity found in Penicillium roqueforti, P.caseicolum,
CC       Aspergillus sojae and A.oryzae.
CC   -!- Optimum pH of 5 for digesting various proteins.
CC   -!- Strong action on protamine and histones.
CC   -!- Insensitive to phosphoramidon.
CC   -!- A distinct A.sojae endopeptidase is larger and has neutral pH
CC       optimum.
CC   -!- Belongs to peptidase family M35.
CC   -!- Formerly EC 3.4.24.4.
PR   PROSITE; PDOC00129;
DR   P46073, MEP20_ASPFL;  Q09016, MEP20_ASPFM;  C5PE62, MEP2_COCP7 ;
DR   C5P507, MEP3_COCP7 ;  C5PIJ9, MEP4_COCP7 ;  C5NZY5, MEP5_COCP7 ;
DR   C5PE18, MEP6_COCP7 ;  C5P3T4, MEP7_COCP7 ;  C5NZL6, MEP8_COCP7 ;
DR   C5G8P3, NPIIA_AJEDR;  C5JKQ0, NPIIA_AJEDS;  E4UUX3, NPIIA_ARTGP;
DR   C5FR79, NPIIA_ARTOC;  A1CIU4, NPIIA_ASPCL;  B0YEV0, NPIIA_ASPFC;
DR   B8NJB2, NPIIA_ASPFN;  Q4WQR6, NPIIA_ASPFU;  Q2UP30, NPIIA_ASPOR;
DR   Q0CMZ3, NPIIA_ASPTN;  A6SBW7, NPIIA_BOTFB;  E3QWD3, NPIIA_COLGM;
DR   Q5AUR8, NPIIA_EMENI;  Q2KH28, NPIIA_MAGO7;  A1DA48, NPIIA_NEOFI;
DR   C1G1N6, NPIIA_PARBD;  C0S3U8, NPIIA_PARBP;  Q0UCJ2, NPIIA_PHANO;
DR   A7F811, NPIIA_SCLS1;  C0IPP1, NPIIA_TRIRU;  C4JLQ3, NPIIA_UNCRE;
DR   C5JHY1, NPIIB_AJEDS;  D4ANL2, NPIIB_ARTBC;  E5R1Z3, NPIIB_ARTGP;
DR   C5FCA7, NPIIB_ARTOC;  B0Y4X9, NPIIB_ASPFC;  B8NWE1, NPIIB_ASPFN;
DR   Q5B7T7, NPIIB_EMENI;  A1CVX6, NPIIB_NEOFI;  Q0V1D7, NPIIB_PHANO;
DR   C0IPP2, NPIIB_TRIRU;  D4DE03, NPIIB_TRIVH;  C4JK49, NPIIB_UNCRE;
DR   D4AM79, NPIIC_ARTBC;  E4UR63, NPIIC_ARTGP;  C5FPC2, NPIIC_ARTOC;
DR   Q4WA45, NPIIC_ASPFU;  D4DGR5, NPIIC_TRIVH;  C4JH04, NPIIC_UNCRE;
DR   D4B639, NPIID_ARTBC;  E4US45, NPIID_ARTGP;  C5FWQ2, NPIID_ARTOC;
DR   D4D616, NPIID_TRIVH;  D4AXC1, NPIIE_ARTBC;  C5FIT1, NPIIE_ARTOC;
DR   D4AJ87, NPIIF_ARTBC;  E4UYQ9, NPIIF_ARTGP;  D4D7X4, NPIIF_TRIVH;
DR   P46076, NPII_ASPOR ;  P47189, PLNC_PENCI ;
//
ID   3.4.24.40
DE   Serralysin.
AN   Escherichia freundii proteinase.
AN   Pseudomonas aeruginosa alkaline protease.
AN   Serratia marcescens extracellular proteinase.
CA   Preferential cleavage of bonds with hydrophobic residues in P1'.
CF   Zinc.
CC   -!- An extracellular endopeptidase from Pseudomonas aeruginosa,
CC       Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.
CC   -!- There is broad specificity in cleavage of the insulin B chain, with
CC       some species variations.
CC   -!- The pH optimum for digesting various proteins is about 9-10.
CC   -!- Belongs to peptidase family M10A.
CC   -!- Formerly EC 3.4.24.4.
PR   PROSITE; PDOC00129;
DR   P23694, PRZN_SERMA ;  P07268, PRZN_SERME ;
//
ID   3.4.24.41
DE   Atrolysin B.
AN   Crotalus atrox metalloendopeptidase b.
AN   Hemorrhagic toxin b.
AN   Ht-b.
CA   Cleavage of 5-His-|-Leu-6, 10-His-|-Leu-11, 14-Ala-|-Leu-15,
CA   16-Tyr-|-Leu-17 and 23-Gly-|-Phe-24 of insulin B chain; identical to the
CA   cleavage of insulin B chain by atrolysin C. Also cleaves Xaa-|-Ser bonds
CA   in glucagon.
CF   Zinc.
CC   -!- From the venom of the western diamondback rattlesnake (Crotalus
CC       atrox).
CC   -!- Belongs to peptidase family M12B.
PR   PROSITE; PDOC00129;
DR   Q90391, VMATB_CROAT;
//
ID   3.4.24.42
DE   Atrolysin C.
AN   Crotalus atrox metalloendopeptidase c.
AN   Hemorrhagic toxin c.
AN   Ht-c.
CA   Cleavage of 5-His-|-Leu-6, 10-His-|-Leu-11, 14-Ala-|-Leu-15,
CA   16-Tyr-|-Leu-17 and 23-Gly-|-Phe-24 of insulin B chain. With small
CA   molecule substrates prefers hydrophobic residue at P2' and small residue
CA   such as Ala, Gly at P1.
CF   Zinc.
CC   -!- Hemorrhagic endopeptidase from the venom of the western diamondback
CC       rattlesnake (Crotalus atrox).
CC   -!- Exist as two forms, c and d.
CC   -!- Digests type IV collagen.
CC   -!- Phosphoramidon inhibits in the 0.1 mM range.
CC   -!- Hemorrhagic toxin-2 of C.ruber ruber has the same molecular weight
CC       and specificity.
CC   -!- Belongs to peptidase family M12B.
PR   PROSITE; PDOC00129;
DR   Q90392, VMATC_CROAT;  P15167, VMATD_CROAT;
//
ID   3.4.24.43
DE   Atroxase.
CA   Cleavage of 5-His-|-Leu-6, 9-Ser-|-His-10, 10-His-|-Leu-11, 14-Ala-|-Leu-
CA   15 and 16-Tyr-|-Leu-17 in insulin B chain.
CF   Zinc.
CC   -!- A nonhemorrhagic endopeptidase from the venom of the western
CC       diamondback rattlesnake (Crotalus atrox).
CC   -!- Cleaves fibrinogen.
CC   -!- Belongs to peptidase family M12B.
PR   PROSITE; PDOC00129;
DR   Q91401, VMATR_CROAT;
//
ID   3.4.24.44
DE   Atrolysin E.
AN   Crotalus atrox metalloendopeptidase e.
AN   Hemorrhagic toxin e.
CA   Cleavage of 3-Asn-|-Gln-4, 9-Ser-|-His-10 and 14-Ala-|-Leu-15 bonds in
CA   insulin B chain and 14-Tyr-|-Gln-15 and 8-Thr-|-Ser-9 in A chain. Cleaves
CA   type IV collagen at 73-Ala-|-Gln-74 in alpha-1-(IV) and at 7-Gly-|-Leu-8
CA   in alpha-2-(IV).
CF   Zinc.
CC   -!- Hemorrhagic endopeptidase from the venom of the western diamondback
CC       rattlesnake (Crotalus atrox).
CC   -!- Digests basement membrane components, including the triple helix of
CC       type IV collagen.
CC   -!- Such action is believed to contribute to the hemorrhagic property by
CC       weakening capillary walls.
CC   -!- Belongs to peptidase family M12B.
PR   PROSITE; PDOC00129;
DR   P34182, HRTE_CROAT ;
//
ID   3.4.24.45
DE   Atrolysin F.
AN   Crotalus atrox metalloendopeptidase f.
AN   Hemorrhagic toxin f.
CA   Cleavage of 2-Val-|-Asn-3, 4-Gln-|-His-5, 6-Leu-|-Cys-7, 10-His-|-Leu-11,
CA   14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 bonds in insulin B chain.
CF   Zinc.
CC   -!- Hemorrhagic endopeptidase from the venom of the western diamondback
CC       rattlesnake (Crotalus atrox).
CC   -!- Digests the gamma chain of fibrinogen.
CC   -!- Belongs to peptidase family M12B.
PR   PROSITE; PDOC00129;
//
ID   3.4.24.46
DE   Adamalysin.
AN   Crotalus adamanteus metalloendopeptidase.
AN   Proteinase I and II.
CA   Cleavage of 1-Phe-|-Val-2, 5-His-|-Leu-6, 14-Ala-|-Leu-15, 15-Leu-|-Tyr-
CA   16, and 16-Tyr-|-Leu-17 of insulin B chain.
CF   Zinc.
CC   -!- From the venom of the eastern diamondback rattlesnake (Crotalus
CC       adamanteus).
CC   -!- Two isoenzymes of approximately 24 kDa that inactivate alpha-1-
CC       proteinase inhibitor by a single cleavage.
CC   -!- Belongs to peptidase family M12B.
PR   PROSITE; PDOC00129;
DR   P34179, VMAD2_CROAD;
//
ID   3.4.24.47
DE   Horrilysin.
AN   Crotalus horridus metalloendopeptidase.
AN   Hemorrhagic proteinase IV.
CA   Cleavage of only the single bond 14-Ala-|-Leu-15 in the insulin B chain,
CA   12-Ser-|-Leu-13 in the A chain, and Ile-|-Gly, Pro-|-Ala, and Ser-|-Trp
CA   in mellitin.
CF   Zinc.
CC   -!- Cleaves basement membrane, hide powder and fibrinogen.
CC   -!- Hemorrhagic endopeptidase from the venom of the timber rattlesnake
CC       (Crotalus horridus horridus).
CC   -!- Belongs to peptidase family M12B.
PR   PROSITE; PDOC00129;
//
ID   3.4.24.48
DE   Ruberlysin.
AN   Crotalus ruber metalloendopeptidase II.
AN   Hemorrhagic metalloproteinase HT-2.
AN   Hemorrhagic toxin II.
CA   Cleavage of 10-His-|-Leu-11, 14-Ala-|-Leu-15, 16-Tyr-|-Leu-17 and
CA   23-Gly-|-Phe-24 bonds of the B chain of insulin; His-|-Pro, Pro-|-Phe,
CA   and Trp-|-Ser of angiotensin I; and Gly-|-Phe of Met enkephalin.
CF   Zinc.
CC   -!- Hemorrhagic endopeptidase from the venom of the red rattlesnake
CC       (Crotalus ruber ruber).
CC   -!- Cleaves fibrinogen.
CC   -!- Belongs to peptidase family M12B.
PR   PROSITE; PDOC00129;
DR   P20897, VMHT2_CRORU;
//
ID   3.4.24.49
DE   Bothropasin.
CA   Cleavage of 5-His-|-Leu-6, 10-His-|-Leu-11, 14-Ala-|-Leu-15,
CA   16-Tyr-|-Leu-17 and 24-Phe-|-Phe-25 in insulin B chain.
CF   Zinc.
CC   -!- Caseinolytic endopeptidase of jararaca snake (Bothrops jararaca)
CC       venom.
CC   -!- Belongs to peptidase family M12B.
PR   PROSITE; PDOC00129;
DR   O93523, VMBOP_BOTJA;
//
ID   3.4.24.50
DE   Bothrolysin.
AN   Bothrops metalloendopeptidase J.
AN   J protease.
CA   Cleavage of 4-Gln-|-His-5, 9-Ser-|-His-10 and 14-Ala-|-Leu-15 of insulin
CA   B chain and Pro-|-Phe of angiotensin I.
CF   Zinc.
CC   -!- Endopeptidase from the venom of the jararaca snake (Bothrops
CC       jararaca).
CC   -!- Insensitive to phosphoramidon at 0.5 mM.
CC   -!- Belongs to peptidase family M12B.
PR   PROSITE; PDOC00129;
DR   P20416, VMBOT_BOTJA;
//
ID   3.4.24.51
DE   Ophiolysin.
AN   Ophiophagus metalloendopeptidase.
CA   Cleavage of 3-Asn-|-Gln-4, 4-Gln-|-His-5, 10-His-|-Leu-11, 14-Ala-|-Leu-
CA   15, and 16-Tyr-|-Leu-17 in insulin B chain.
CF   Zinc.
CC   -!- Endopeptidase from the venom of the king cobra (Ophiophagus hannah).
CC   -!- Belongs to peptidase family M12B.
PR   PROSITE; PDOC00129;
//
ID   3.4.24.52
DE   Trimerelysin I.
AN   Hemorrhagic proteinase HR1a.
AN   Trimeresurus metalloendopeptidase I.
CA   Cleavage of only two bonds: 10-His-|-Leu-11 and 14-Ala-|-Leu-15, in the
CA   insulin B chain.
CF   Zinc.
CC   -!- Hemorrhagic endopeptidase of pI 4.4 from the venom of the habu snake
CC       (Trimeresurus flavoviridis).
CC   -!- Belongs to peptidase family M12B.
PR   PROSITE; PDOC00129;
DR   P20164, HR1B_PROFL ;
//
ID   3.4.24.53
DE   Trimerelysin II.
AN   Proteinase H(2).
AN   Trimeresurus metalloendopeptidase II.
CA   Cleavage of 3-Asn-|-Gln-4, 10-His-|-Leu-11 and 14-Ala-|-Leu-15 in the
CA   insulin B chain, and the bond Z-Gly-Pro-|-Leu-Gly-Pro in a small molecule
CA   substrate of microbial collagenase.
CF   Zinc.
CC   -!- Nonhemorrhagic endopeptidase from the venom of the habu snake
CC       (Trimeresurus flavoviridis).
CC   -!- Belongs to peptidase family M12B.
PR   PROSITE; PDOC00129;
DR   P14530, HR2A_PROFL ;  P20165, VMHR2_PROFL;
//
ID   3.4.24.54
DE   Mucrolysin.
AN   Mucrotoxin A.
AN   Trimeresurus metalloendopeptidase A.
CA   Cleavage of 9-Ser-|-His-10, 10-His-|-Leu-11, 14-Ala-|-Leu-15,
CA   15-Leu-|-Tyr-16 and 16-Tyr-|-Leu-17 bonds in the insulin B chain.
CF   Zinc.
CC   -!- Hemorrhagic and fibrinogenolytic endopeptidase from the Chinese habu
CC       snake (Trimeresurus mucrosquamatus) venom.
CC   -!- Belongs to peptidase family M12B.
PR   PROSITE; PDOC00129;
//
ID   3.4.24.55
DE   Pitrilysin.
AN   Protease III.
AN   Protease Pi.
CA   Preferential cleavage of 16-Tyr-|-Leu-17 and 25-Phe-|-Tyr-26 bonds of
CA   oxidized insulin B chain. Also acts on other substrates of Mw less than 7
CA   kDa such as insulin and glucagon.
CF   Zinc.
CC   -!- From the periplasmic space of Escherichia coli.
CC   -!- Inhibited by EDTA and 1,10-phenanthroline; not thiol dependent.
CC   -!- Belongs to peptidase family M16.
CC   -!- Formerly EC 3.4.99.44.
PR   PROSITE; PDOC00130;
DR   Q8X6M8, PTRA_ECO57 ;  Q8CVS2, PTRA_ECOL6 ;  P05458, PTRA_ECOLI ;
DR   Q8Z418, PTRA_SALTI ;  Q8ZMB5, PTRA_SALTY ;  Q83QC3, PTRA_SHIFL ;
//
ID   3.4.24.56
DE   Insulysin.
AN   Insulin protease.
AN   Insulin-degrading enzyme.
AN   Insulinase.
CA   Degradation of insulin, glucagon and other polypeptides. No action on
CA   proteins.
CF   Zinc.
CC   -!- Cytosolic enzyme, known from mammals and Drosophila melanogaster.
CC   -!- Inhibited by bacitracin, chelating agents EDTA and 1,10-
CC       phenanthroline, and by thiol-blocking reagents such as
CC       N-ethylmaleimide, but not by phosphoramidon.
CC   -!- Belongs to peptidase family M16.
CC   -!- Formerly EC 3.4.22.11, EC 3.4.99.10 and EC 3.4.99.45.
PR   PROSITE; PDOC00130;
DR   Q24K02, IDE_BOVIN  ;  P22817, IDE_DROME  ;  P14735, IDE_HUMAN  ;
DR   Q9JHR7, IDE_MOUSE  ;  P35559, IDE_RAT    ;
//
ID   3.4.24.57
DE   O-sialoglycoprotein endopeptidase.
AN   Glycoprotease.
CA   Hydrolysis of O-sialoglycoproteins; cleaves 31-Arg-|-Asp-32 bond in
CA   glycophorin A. Does not cleave unglycosylated proteins, desialylated
CA   glycoproteins or glycoproteins that are only N-glycosylated.
CC   -!- Inhibited by EDTA (100 mM) and 1,10-phenanthroline.
CC   -!- Belongs to peptidase family M22.
PR   PROSITE; PDOC00779;
//
ID   3.4.24.58
DE   Russellysin.
AN   Blood-coagulation factor X-activating enzyme.
AN   Russell's viper venom factor X activator.
AN   RVV-X.
CA   Specifically activates several components of the blood clotting system,
CA   including coagulation factor X, coagulation factor IX and protein C by
CA   cleavage of Arg-|-Xaa bonds. Has no action on insulin B chain.
CF   Calcium; Zinc.
CC   -!- Belongs to peptidase family M12B.
PR   PROSITE; PDOC00129;
DR   P86536, RVVX_DABRR ;  Q7LZ61, RVVX_DABRU ;  Q7T046, RVVX_MACLB ;
//
ID   3.4.24.59
DE   Mitochondrial intermediate peptidase.
CA   Release of an N-terminal octapeptide as second stage of processing of
CA   some proteins imported into the mitochondrion.
CF   Zinc.
CC   -!- Natural substrates are precursor proteins that have already been
CC       processed by mitochondrial processing peptidase.
CC   -!- Belongs to peptidase family M3.
PR   PROSITE; PDOC00129;
DR   Q99797, MIPEP_HUMAN;  A6H611, MIPEP_MOUSE;  Q5RF14, MIPEP_PONAB;
DR   Q01992, MIPEP_RAT  ;  P0CQ19, PMIP1_CRYNB;  P0CQ18, PMIP1_CRYNJ;
DR   P0CQ21, PMIP2_CRYNB;  P0CQ20, PMIP2_CRYNJ;  Q753X4, PMIP_ASHGO ;
DR   A1CTP5, PMIP_ASPCL ;  B0Y7Q2, PMIP_ASPFC ;  Q4WMU9, PMIP_ASPFU ;
DR   A2QWM4, PMIP_ASPNC ;  Q2UN31, PMIP_ASPOR ;  Q0CI79, PMIP_ASPTN ;
DR   A6SHZ5, PMIP_BOTFB ;  Q59RK9, PMIP_CANAL ;  Q6FW88, PMIP_CANGA ;
DR   Q2HFL8, PMIP_CHAGB ;  Q1E8M9, PMIP_COCIM ;  A8N2T3, PMIP_COPC7 ;
DR   Q6Y5M6, PMIP_COPDI ;  Q6Y5M7, PMIP_COPSC ;  Q6BJ61, PMIP_DEBHA ;
DR   Q6CVF7, PMIP_KLULA ;  B0CRC2, PMIP_LACBS ;  Q6VMB4, PMIP_LEUGO ;
DR   A5E4V6, PMIP_LODEL ;  A4RF25, PMIP_MAGO7 ;  A8QB25, PMIP_MALGO ;
DR   A1DMR2, PMIP_NEOFI ;  Q7SDD5, PMIP_NEUCR ;  Q0TXL7, PMIP_PHANO ;
DR   A5DI46, PMIP_PICGU ;  A3LUT4, PMIP_PICST ;  Q6Y5M5, PMIP_PLEDJ ;
DR   P37932, PMIP_SCHCO ;  Q10415, PMIP_SCHPO ;  A7E7L8, PMIP_SCLS1 ;
DR   Q4PBS8, PMIP_USTMA ;  A7TSL2, PMIP_VANPO ;  Q6CHD6, PMIP_YARLI ;
DR   A6ZZI7, PMIP_YEAS7 ;  P35999, PMIP_YEAST ;
//
ID   3.4.24.60
DE   Dactylysin.
AN   Peptide hormone inactivating endopeptidase.
CA   Hydrolysis of peptides of at least six residues, with bulky hydrophobic
CA   residues in the P1' position. Shows a preference for hydrophobic doublets
CA   such as -Phe-|-Phe- and -Phe-|-Leu- in somatostatin-(1-14)-peptide and
CA   dynorphin A-(1-6)-peptide, respectively.
CC   -!- An endopeptidase of 100 kDa secreted from the skin of Xenopus laevis.
CC   -!- Resembles neprilysin in insensitivity to 1 uM captopril, but differs
CC       in being insensitive to thiorphan and unable to digest (5-Met)-
CC       enkephalin, (5-Leu)-enkephalin, oxytocin and substance P-(7-11)-
CC       peptide.
//
ID   3.4.24.61
DE   Nardilysin.
AN   N-arginine dibasic convertase.
AN   NRD convertase.
CA   Hydrolysis of polypeptides, preferably at -Xaa-|-Arg-Lys-, and less
CA   commonly at -Arg-|-Arg-Xaa-, in which Xaa is not Arg or Lys.
CF   Zinc.
CC   -!- Unusually for a metallopeptidase, inhibited by bestatin, amastin and
CC       ethylmaleimide.
CC   -!- Belongs to peptidase family M16.
PR   PROSITE; PDOC00130;
DR   O43847, NRDC_HUMAN ;  Q8BHG1, NRDC_MOUSE ;  Q5R4H6, NRDC_PONAB ;
DR   P47245, NRDC_RAT   ;
//
ID   3.4.24.62
DE   Magnolysin.
AN   Neurosecretory granule protease cleaving pro-ocytocin/neurophysin.
CA   Hydrolysis of polypeptides with Arg or Lys in P1 and P2, e.g. to
CA   hydrolyze pro-oxytocin at -Lys-Arg-|-Ala-Val-. The specificity further
CA   depends on the organization of a beta-turn-alpha-helix of nine or more
CA   residues containing the paired basic amino acids near the center.
CC   -!- Inhibited by EDTA.
//
ID   3.4.24.63
DE   Meprin B.
CA   Hydrolysis of proteins, including azocasein, and peptides. Hydrolysis of
CA   5-His-|-Leu-6, 6-Leu-|-Cys-7, 14-Ala-|-Leu-15 and 19-Cys-|-Gly-20 bonds
CA   in insulin B chain.
CF   Zinc.
CC   -!- Inhibited by EDTA and 1,10-phenanthroline, but not by phosphoramidon,
CC       captopril or thiorphan.
CC   -!- Belongs to peptidase family M12A.
PR   PROSITE; PDOC00129;
DR   Q16820, MEP1B_HUMAN;  Q61847, MEP1B_MOUSE;  P28826, MEP1B_RAT  ;
//
ID   3.4.24.64
DE   Mitochondrial processing peptidase.
AN   Processing enhancing peptidase.
CA   Release of N-terminal transit peptides from precursor proteins imported
CA   into the mitochondrion, typically with Arg in position P2.
CF   Zinc.
CC   -!- Known from the mitochondrial matrix of fungi and mammals.
CC   -!- Belongs to peptidase family M16.
CC   -!- Formerly EC 3.4.99.41.
PR   PROSITE; PDOC00130;
DR   Q9ZU25, MPPA1_ARATH;  O04308, MPPA2_ARATH;  P97997, MPPA_BLAEM ;
DR   Q0P5M8, MPPA_BOVIN ;  Q10713, MPPA_HUMAN ;  Q9DC61, MPPA_MOUSE ;
DR   P23955, MPPA_NEUCR ;  Q5R513, MPPA_PONAB ;  P20069, MPPA_RAT   ;
DR   O94745, MPPA_SCHPO ;  P29677, MPPA_SOLTU ;  P11914, MPPA_YEAST ;
DR   Q42290, MPPB_ARATH ;  Q00302, MPPB_BLAEM ;  Q3SZ71, MPPB_BOVIN ;
DR   Q4W6B5, MPPB_DICDI ;  O75439, MPPB_HUMAN ;  Q9Y8B5, MPPB_LENED ;
DR   Q9CXT8, MPPB_MOUSE ;  P11913, MPPB_NEUCR ;  Q5REK3, MPPB_PONAB ;
DR   Q03346, MPPB_RAT   ;  Q9P7X1, MPPB_SCHPO ;  P10507, MPPB_YEAST ;
//
ID   3.4.24.65
DE   Macrophage elastase.
AN   Matrix metalloproteinase 12.
AN   Metalloelastase.
CA   Hydrolysis of soluble and insoluble elastin. Specific cleavages are also
CA   produced at 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 in the B chain of
CA   insulin.
CF   Calcium; Zinc.
CC   -!- Belongs to peptidase family M10B.
PR   PROSITE; PDOC00129;
DR   P39900, MMP12_HUMAN;  P34960, MMP12_MOUSE;  P79227, MMP12_RABIT;
DR   Q63341, MMP12_RAT  ;
//
ID   3.4.24.66
DE   Choriolysin L.
AN   Low choriolytic enzyme.
AN   Teleost hatching enzyme.
CA   Hydrolysis of the inner layer of fish egg envelope. Also hydrolysis of
CA   casein and small molecule substrates such as succinyl-Leu-Leu-
CA   Val-Tyr-|-7-(4-methyl)coumarylamide.
CF   Zinc.
CC   -!- Belongs to peptidase family M12A.
PR   PROSITE; PDOC00129;
DR   P31579, LCE_ORYLA  ;
//
ID   3.4.24.67
DE   Choriolysin H.
AN   High choriolytic enzyme.
AN   Teleost hatching enzyme.
CA   Hydrolysis of the inner layer of fish egg envelope. Also hydrolysis of
CA   casein and small molecule substrates such as succinyl-Leu-Leu-
CA   Val-Tyr-|-7-(4-methyl)coumarylamide.
CF   Zinc.
CC   -!- Belongs to peptidase family M12A.
PR   PROSITE; PDOC00129;
DR   P31580, HCE1_ORYLA ;  P31581, HCE2_ORYLA ;
//
ID   3.4.24.68
DE   Tentoxilysin.
AN   Tetanus neurotoxin.
CA   Hydrolysis of 76-Gln-|-Phe-77 bond in synaptobrevin 2.
CF   Zinc.
CC   -!- Belongs to peptidase family M27.
PR   PROSITE; PDOC00129;
DR   P04958, TETX_CLOTE ;
//
ID   3.4.24.69
DE   Bontoxilysin.
AN   Botulinum neurotoxin.
CA   Limited hydrolysis of proteins of the neuroexocytosis apparatus,
CA   synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule
CA   substrates.
CF   Zinc.
CC   -!- Belongs to peptidase family M27.
PR   PROSITE; PDOC00129;
DR   A5HZZ9, BXA1_CLOBH ;  P10845, BXA1_CLOBO ;  Q45894, BXA2_CLOBO ;
DR   B1INP5, BXB_CLOBK  ;  P10844, BXB_CLOBO  ;  P18640, BXC1_CLOBO ;
DR   P19321, BXD_CLOBO  ;  Q00496, BXE_CLOBO  ;  P30995, BXE_CLOBU  ;
DR   P30996, BXF_CLOBO  ;  Q60393, BXG_CLOBO  ;
//
ID   3.4.24.70
DE   Oligopeptidase A.
CA   Hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly
CA   occur as P1 or P1' residues, but more distant residues are also
CA   important, as is shown by the fact that Z-Gly-Pro-Gly-|-Gly-Pro-Ala is
CA   cleaved, but not Z-(Gly)(5).
CF   Zinc.
CC   -!- Differs from thimet oligopeptidase in lack of thiol activation.
CC   -!- Belongs to peptidase family M3.
PR   PROSITE; PDOC00129;
DR   P27298, OPDA_ECOLI ;  P44573, OPDA_HAEIN ;  P27237, OPDA_SALTY ;
//
ID   3.4.24.71
DE   Endothelin-converting enzyme 1.
AN   ECE-1.
CA   Hydrolysis of the 21-Trp-|-Val-22 bond in big endothelin to form
CA   endothelin 1.
CF   Zinc.
CC   -!- Phosphoramidon-sensitive.
CC   -!- Belongs to peptidase family M13.
PR   PROSITE; PDOC00129;
DR   P42891, ECE1_BOVIN ;  P97739, ECE1_CAVPO ;  P42892, ECE1_HUMAN ;
DR   Q4PZA2, ECE1_MOUSE ;  P42893, ECE1_RAT   ;  Q10711, ECE2_BOVIN ;
DR   O60344, ECE2_HUMAN ;  Q80Z60, ECE2_MOUSE ;
//
ID   3.4.24.72
DE   Fibrolase.
AN   Fibrinolytic proteinase.
CA   Hydrolysis of 14-Ala-|-Leu-15 in insulin B chain and 413-Lys-|-Leu-414 in
CA   alpha-chain of fibrinogen.
CF   Zinc.
CC   -!- Belongs to peptidase family M12.
PR   PROSITE; PDOC00129;
DR   P28891, VMFIB_AGKCO;  P83255, VMFIB_MACLB;
//
ID   3.4.24.73
DE   Jararhagin.
AN   HF2-proteinase.
CA   Cleavage of 10-His-|-Leu-11, 14-Ala-|-Leu-15, 16-Tyr-|-Leu-17 and
CA   24-Phe-|-Phe-25 bonds in insulin B chain.
CF   Zinc.
CC   -!- Hemorrhagic endopeptidase from the venom of the jararaca snake.
CC   -!- Belongs to peptidase family M12.
PR   PROSITE; PDOC00129;
DR   P30431, VMJAR_BOTJA;
//
ID   3.4.24.74
DE   Fragilysin.
AN   Bacteroides fragilis enterotoxin.
CA   Broad proteolytic specificity, bonds hydrolyzed includes -Gly-|-Leu-,
CA   -Met-|-Leu-, -Phe-|-Leu-, -Cys-|-Leu-, -Leu-|-Gly-.
CF   Zinc.
CC   -!- Thought to be a cause of diarrhea.
CC   -!- Hydrolyzes extracellular matrix proteins, and disrupts tight
CC       junctions of intstinal cells.
CC   -!- Also degrades intracellular, cytoskeletal proteins actin, myosin and
CC       others.
CC   -!- Belongs to peptidase family M10.
DR   P54355, ENTM_BACFR ;
//
ID   3.4.24.75
DE   Lysostaphin.
AN   Glycyl-glycine endopeptidase.
CA   Hydrolysis of the -Gly-|-Gly- bond in the pentaglycine inter-peptide link
CA   joining staphylococcal cell wall peptidoglycans.
CF   Zinc.
CC   -!- Lyses cells of Staphylococcus aureus in particular, by its action on
CC       the cross-bridge of the cell wall.
CC   -!- Belongs to peptidase family M23.
DR   O05156, ALE1_STACP ;  P10547, LSTP_STASI ;  P10548, LSTP_STAST ;
DR   O33599, LYTM_STAA8 ;  Q5HJ99, LYTM_STAAC ;  Q99WV0, LYTM_STAAM ;
DR   Q7A7T0, LYTM_STAAN ;  Q6GK35, LYTM_STAAR ;  Q6GCJ6, LYTM_STAAS ;
DR   Q8NYG1, LYTM_STAAW ;
//
ID   3.4.24.76
DE   Flavastacin.
CA   Hydrolyzes polypeptides on the amino-side of Asp in -Xaa-|-Asp-. Acts
CA   very slowly on -Xaa-|-Glu.
CF   Zinc.
CC   -!- The specificity is similar to that of EC 3.4.24.33, but the two are
CC       reported to be structurally dissimilar.
CC   -!- Belongs to peptidase family M12.
DR   Q47899, FLVS_FLAME ;
//
ID   3.4.24.77
DE   Snapalysin.
AN   Small neutral protease.
CA   Hydrolyzes proteins with a preference for Tyr or Phe in the P1' position.
CA   Has no action on amino-acid p-nitroanilides.
CF   Zinc.
CC   -!- Belongs to peptidase family M7.
PR   PROSITE; PDOC00129;
DR   P43164, SNPA1_STRCO;  P0A3Z7, SNPA2_STRCO;  P0A3Z8, SNPA2_STRLI;
DR   P56406, SNPA_STRCS ;  P43163, SNPA_STRS5 ;
//
ID   3.4.24.78
DE   GPR endopeptidase.
AN   Germination protease.
AN   Germination proteinase.
AN   Spore protease.
CA   Endopeptidase action with P4 Glu or Asp, P1 preferably Glu > Asp,
CA   P1' hydrophobic and P2' Ala.
CC   -!- Initiates the degradation of small, acid-soluble proteins during
CC       spore germination in Bacillus megaterium.
CC   -!- Belongs to peptidase family M63.
DR   A7Z6W8, GPR_BACA2  ;  C3P8M7, GPR_BACAA  ;  C3L5S4, GPR_BACAC  ;
DR   Q81LR5, GPR_BACAN  ;  B7JNV3, GPR_BACC0  ;  Q730L4, GPR_BACC1  ;
DR   B7IYH4, GPR_BACC2  ;  C1ESL5, GPR_BACC3  ;  B7HCU7, GPR_BACC4  ;
DR   B7HPM0, GPR_BACC7  ;  A7GT16, GPR_BACCN  ;  B9IY88, GPR_BACCQ  ;
DR   Q818E2, GPR_BACCR  ;  Q634M0, GPR_BACCZ  ;  Q9KD78, GPR_BACHD  ;
DR   Q6HDK0, GPR_BACHK  ;  Q65H47, GPR_BACLD  ;  P22321, GPR_BACMQ  ;
DR   A8FFD9, GPR_BACP2  ;  P22322, GPR_BACSU  ;  A9VHU8, GPR_BACWK  ;
DR   Q97JJ9, GPR_CLOAB  ;  Q0TNR9, GPR_CLOP1  ;  Q8XIS3, GPR_CLOPE  ;
DR   Q0SRD5, GPR_CLOPS  ;  P59406, GPR_CLOTE  ;  C5D4U8, GPR_GEOSW  ;
DR   Q8CXC9, GPR_OCEIH  ;  Q8RB77, GPR_THETN  ;
//
ID   3.4.24.79
DE   Pappalysin-1.
AN   Insulin-like growth factor binding protein-4 protease.
AN   Pregnancy-associated plasma protein-A.
CA   Cleavage of the 135-Met-|-Lys-136 bond in insulin-like growth factor
CA   binding protein (IGFBP)-4, and the 143-Ser-|-Lys-144 bond in IGFBP-5.
CF   Zinc.
CC   -!- Circulates in human pregnancy mainly as a complex with the proform of
CC       eosinophil major basic protein, which acts as an inhibitor of the
CC       peptidase.
CC   -!- The rate of hydrolysis of IGFBP-4 is increased about 20-fold by the
CC       presence of insulin-like growth factor (IGF), whereas that of IGFBP-5
CC       is decreased about two-fold.
CC   -!- Belongs to peptidase family M43.
PR   PROSITE; PDOC00129;
DR   Q13219, PAPP1_HUMAN;  Q8R4K8, PAPP1_MOUSE;
//
ID   3.4.24.80
DE   Membrane-type matrix metalloproteinase-1.
AN   Matrix metalloproteinase 14.
CA   Endopeptidase activity. Activates progelatinase A by cleavage of the
CA   propeptide at 37-Asn-|-Leu-38. Other bonds hydrolyzed include
CA   35-Gly-|-Ile-36 in the propeptide of collagenase 3, and 341-Asn-|-Phe-
CA   342, 441-Asp-|-Leu-442 and 354-Gln-|-Thr-355 in the aggrecan
CA   interglobular domain.
CF   Zinc.
CC   -!- Believed to play an important role in the activation of progelatinase
CC       A at cell surfaces.
CC   -!- Belongs to peptidase family M10.
PR   PROSITE; PDOC00129;
DR   Q9GLE4, MMP14_BOVIN;  P50281, MMP14_HUMAN;  P53690, MMP14_MOUSE;
DR   Q9XT90, MMP14_PIG  ;  Q5RES1, MMP14_PONAB;  Q95220, MMP14_RABIT;
DR   Q10739, MMP14_RAT  ;
//
ID   3.4.24.81
DE   ADAM10 endopeptidase.
AN   Kuzbanian protein.
AN   Myelin-associated disintegrin metalloproteinase.
CA   Endopeptidase of broad specificity.
CF   Zinc.
CC   -!- Partially responsible for the 'alpha-secretase' activity in brain
CC       that degrades the potentially harmful beta-amyloid peptide.
CC   -!- Work with ADAM10-deficient mice supports a role in Notch signaling.
CC   -!- Belongs to peptidase family M12.
PR   PROSITE; PDOC00129;
DR   Q10741, ADA10_BOVIN;  O14672, ADA10_HUMAN;  O35598, ADA10_MOUSE;
DR   O77633, ADA10_PIG  ;  Q10743, ADA10_RAT  ;  Q8JIY1, ADA10_XENLA;
//
ID   3.4.24.82
DE   ADAMTS-4 endopeptidase.
AN   Aggrecanase-1.
CA   Glutamyl endopeptidase; bonds cleaved include 370-Thr-Glu-Gly-Glu-|-Ala-
CA   Arg-Gly-Ser-377 in the interglobular domain of mammalian aggrecan.
CF   Zinc.
CC   -!- Thought to be biologically significant for the degradation of the
CC       aggrecan component of cartilage matrix.
CC   -!- Belongs to peptidase family M12.
PR   PROSITE; PDOC00129;
DR   Q9TT93, ATS4_BOVIN ;  O75173, ATS4_HUMAN ;  Q8BNJ2, ATS4_MOUSE ;
DR   Q5RFQ8, ATS4_PONAB ;  Q9ESP7, ATS4_RAT   ;
//
ID   3.4.24.83
DE   Anthrax lethal factor endopeptidase.
AN   Lethal toxin.
CA   Preferred amino acids around the cleavage site can be denoted
CA   BBBBxHx-|-H, in which B denotes Arg or Lys, H denotes a hydrophobic amino
CA   acid, and x is any amino acid. The only known protein substrates are
CA   mitogen-activated protein (MAP) kinase kinases.
CF   Zinc.
CC   -!- From the bacterium Bacilus anthracis that causes anthrax.
CC   -!- One of three proteins that are collectively termed anthrax toxin.
CC   -!- Cleaves several MAP kinase kinases near their N-termini, preventing
CC       them from phosphorylating the downstream mitogen-activated protein
CC       kinases.
CC   -!- Belongs to peptidase family M34.
PR   PROSITE; PDOC00129;
DR   P15917, LEF_BACAN  ;
//
ID   3.4.24.84
DE   Ste24 endopeptidase.
AN   CAAX prenyl protease 1.
AN   Prenyl protein-specific endoprotease 1.
CA   The peptide bond hydrolyzed can be designated -C-|-A-A-X in which C is an
CA   S-isoprenylated cysteine residue, A is usually aliphatic and X is the
CA   C-terminal residue of the substrate protein, and may be any of several
CA   amino acids.
CF   Zinc.
CC   -!- One of two enzymes that can catalyze this processing step for mating
CC       a-factor in Saccharomyces cerevisiae.
CC   -!- Subsequently, the S-isoprenylated cysteine residue that forms the new
CC       C-terminus is methyl-esterified and forms a hydrophobic membrane-
CC       anchor.
CC   -!- Belongs to peptidase family M48.
PR   PROSITE; PDOC00129;
DR   Q8RX88, FACE1_ARATH;  Q54FH7, FACE1_DICDI;  O75844, FACE1_HUMAN;
DR   Q80W54, FACE1_MOUSE;  Q6EPN8, FACE1_ORYSJ;  Q10071, STE24_SCHPO;
DR   P47154, STE24_YEAST;
//
ID   3.4.24.85
DE   S2P endopeptidase.
AN   Membrane-bound transcription factor site 2 protease.
AN   Site-2 protease.
AN   Sterol-regulatory element-binding proteins intramembrane protease.
CA   Cleaves several transcription factors that are type-2 transmembrane
CA   proteins within membrane-spanning domains. Known substrates include
CA   sterol regulatory element-binding protein (SREBP) -1, SREBP-2 and forms
CA   of the transcriptional activator ATF6. SREBP-2 is cleaved at the site
CA   477-DRSRILL-|-CVLTFLCLSFNPLTSLLQWGGA-505. The residues Asn-Pro,
CA   11 residues distal to the site of cleavage in the membrane-spanning
CA   domain, are important for cleavage by S2P endopeptidase. Replacement of
CA   either of these residues does not prevent cleavage, but there is no
CA   cleavage if both of these residues are replaced.
CF   Zinc.
CC   -!- The transcription factors SREBP-1 and -2 are synthesized as precursor
CC       proteins that are attached to the membranes of the endoplasmic
CC       reticulum and two cleavages are needed to release the active factor
CC       so that it can move to the nucleus.
CC   -!- This enzyme cleaves the second of these, and is thus the 'site 2
CC       protease', S2P.
CC   -!- Belongs to peptidase family M50.
PR   PROSITE; PDOC00129;
DR   Q0III2, MBTP2_BOVIN;  O54862, MBTP2_CRIGR;  O43462, MBTP2_HUMAN;
DR   Q8CHX6, MBTP2_MOUSE;  Q5RAC8, MBTP2_PONAB;
//
ID   3.4.24.86
DE   ADAM 17 endopeptidase.
AN   TACE.
AN   Tumor necrosis factor alpha-converting enzyme.
CA   Narrow endopeptidase specificity. Cleaves Pro-Leu-Ala-Gln-Ala-|-Val-
CA   Arg-Ser-Ser-Ser in the membrane-bound, 26-kDa form of tumor necrosis
CA   factor alpha (TNF-alpha). Similarly cleaves other membrane-anchored,
CA   cell-surface proteins to 'shed' the extracellular domains.
CF   Zinc.
CC   -!- In vivo, the cleavage of tumor necrosis factor alpha precursor
CC       releases the soluble, 17-kDa TNF-alpha, which induces inflammation.
CC   -!- Belongs to peptidase family M12.
PR   PROSITE; PDOC00129;
DR   P78536, ADA17_HUMAN;  Q9Z0F8, ADA17_MOUSE;  O77636, ADA17_PIG  ;
DR   Q9Z1K9, ADA17_RAT  ;
//
ID   3.4.24.87
DE   ADAMTS13 endopeptidase.
AN   ADAMTS VWF cleaving metalloprotease.
AN   ADAMTS13 peptidase.
AN   Upshaw factor.
AN   Von Willebrand factor cleaving protease.
AN   VWF-cleaving protease.
AN   VWF-degrading protease.
CA   The enzyme cleaves the von Willebrand factor at bond Tyr(842)-|-Met(843)
CA   within the A2 domain.
CC   -!- Belongs to peptidase family M12.
PR   PROSITE; PDOC00129;
DR   Q76LX8, ATS13_HUMAN;  Q769J6, ATS13_MOUSE;
//
ID   3.4.25.1
DE   Proteasome endopeptidase complex.
AN   Ingensin.
AN   Lens neutral proteinase.
AN   Macropain.
AN   Multicatalytic endopeptidase complex.
AN   Multicatalytic proteinase (complex).
AN   Prosome.
AN   Proteasome.
CA   Cleavage of peptide bonds with very broad specificity.
CC   -!- A 20-S protein composed of 28 subunits arranged in four rings of
CC       seven.
CC   -!- The outer rings are composed of alpha subunits, but the beta subunits
CC       forming the inner rings are responsible for peptidase activity.
CC   -!- In eukaryotic organisms there are up to seven different types of beta
CC       subunits, three of which may carry the N-terminal threonine residues
CC       that are the nucleophiles in catalysis, and show different
CC       specificities.
CC   -!- The molecule is barrel-shaped, and the active sites are on the inner
CC       surfaces.
CC   -!- Terminal apertures restrict access of substrates to the active sites.
CC   -!- Inhibited by mercurial reagents and some inhibitors of serine
CC       endopeptidases.
CC   -!- Belongs to peptidase family T1.
CC   -!- Formerly EC 3.4.22.21, EC 3.4.24.5 and EC 3.4.99.46.
PR   PROSITE; PDOC00326;
PR   PROSITE; PDOC00668;
DR   A7KE01, PB6LA_SALSA;  A7KII6, PB6LB_SALSA;  P34066, PSA1A_ARATH;
DR   O23712, PSA1B_ARATH;  Q3T0X5, PSA1_BOVIN ;  O44156, PSA1_CAEEL ;
DR   O42265, PSA1_CHICK ;  Q27562, PSA1_DICDI ;  P12881, PSA1_DROME ;
DR   Q8SQS5, PSA1_ENCCU ;  Q5V2X8, PSA1_HALMA ;  Q9V2V6, PSA1_HALVD ;
DR   P25786, PSA1_HUMAN ;  Q4R3H2, PSA1_MACFA ;  Q9R1P4, PSA1_MOUSE ;
DR   P52428, PSA1_ORYSJ ;  Q5REN2, PSA1_PONAB ;  P18420, PSA1_RAT   ;
DR   Q53080, PSA1_RHOER ;  O14250, PSA1_SCHPO ;  Q9GU37, PSA1_TRYBB ;
DR   O96788, PSA1_TRYBR ;  P92188, PSA1_TRYCR ;  P40302, PSA1_YEAST ;
DR   O23708, PSA2A_ARATH;  Q8L4A7, PSA2B_ARATH;  Q3T0Y5, PSA2_BOVIN ;
DR   Q27488, PSA2_CAEEL ;  O73672, PSA2_CARAU ;  Q54DM7, PSA2_DICDI ;
DR   P40301, PSA2_DROME ;  Q5V1D4, PSA2_HALMA ;  Q9V2V5, PSA2_HALVD ;
DR   P25787, PSA2_HUMAN ;  P49722, PSA2_MOUSE ;  Q8X077, PSA2_NEUCR ;
DR   A2YVR7, PSA2_ORYSI ;  Q10KF0, PSA2_ORYSJ ;  P17220, PSA2_RAT   ;
DR   Q53084, PSA2_RHOER ;  O94579, PSA2_SCHPO ;  Q9U793, PSA2_TRYBB ;
DR   P24495, PSA2_XENLA ;  P23639, PSA2_YEAST ;  P90513, PSA3_ACACA ;
DR   O23715, PSA3_ARATH ;  Q58DU5, PSA3_BOVIN ;  Q09583, PSA3_CAEEL ;
DR   Q27563, PSA3_DICDI ;  Q9V5C6, PSA3_DROME ;  Q8SQP9, PSA3_ENCCU ;
DR   P25788, PSA3_HUMAN ;  O70435, PSA3_MOUSE ;  Q9LSU0, PSA3_ORYSJ ;
DR   P18422, PSA3_RAT   ;  O59770, PSA3_SCHPO ;  O24362, PSA3_SPIOL ;
DR   P21242, PSA3_YEAST ;  A2Y9X7, PSA4A_ORYSI;  P0C1G8, PSA4A_ORYSJ;
DR   P0C8Y9, PSA4B_ORYSI;  Q5VRG3, PSA4B_ORYSJ;  Q9VA12, PSA4L_DROME;
DR   O81148, PSA4_ARATH ;  Q3ZCK9, PSA4_BOVIN ;  Q9N599, PSA4_CAEEL ;
DR   P34119, PSA4_DICDI ;  P18053, PSA4_DROME ;  Q8SRU7, PSA4_ENCCU ;
DR   P25789, PSA4_HUMAN ;  Q4R932, PSA4_MACFA ;  Q9R1P0, PSA4_MOUSE ;
DR   O82530, PSA4_PETHY ;  P21670, PSA4_RAT   ;  Q09682, PSA4_SCHPO ;
DR   P52427, PSA4_SPIOL ;  P23638, PSA4_YEAST ;  O81149, PSA5A_ARATH;
DR   Q42134, PSA5B_ARATH;  Q5E987, PSA5_BOVIN ;  Q95008, PSA5_CAEEL ;
DR   Q55G04, PSA5_DICDI ;  Q95083, PSA5_DROME ;  Q8SRU3, PSA5_ENCCU ;
DR   Q94561, PSA5_ENTHI ;  P28066, PSA5_HUMAN ;  Q9Z2U1, PSA5_MOUSE ;
DR   Q9LSU1, PSA5_ORYSJ ;  P34064, PSA5_RAT   ;  Q9UT97, PSA5_SCHPO ;
DR   Q9M4T8, PSA5_SOYBN ;  Q9XZG5, PSA5_TRYBB ;  P32379, PSA5_YEAST ;
DR   O81146, PSA6A_ARATH;  O81147, PSA6B_ARATH;  Q2YDE4, PSA6_BOVIN ;
DR   O17586, PSA6_CAEEL ;  Q54XM7, PSA6_DICDI ;  Q9XZJ4, PSA6_DROME ;
DR   P60900, PSA6_HUMAN ;  Q9QUM9, PSA6_MOUSE ;  Q9LSU3, PSA6_ORYSJ ;
DR   P60901, PSA6_RAT   ;  O94517, PSA6_SCHPO ;  O48551, PSA6_SOYBN ;
DR   Q9XG77, PSA6_TOBAC ;  P21243, PSA6_YEAST ;  P22769, PSA71_DROME;
DR   O16811, PSA71_DROVI;  Q24178, PSA72_DROME;  Q27575, PSA73_DROME;
DR   O16812, PSA73_DROVI;  P30186, PSA7A_ARATH;  A2YXU2, PSA7A_ORYSI;
DR   Q6YT00, PSA7A_ORYSJ;  Q9PVY6, PSA7A_XENLA;  O24616, PSA7B_ARATH;
DR   A2Z3I9, PSA7B_ORYSI;  Q0J006, PSA7B_ORYSJ;  Q9PVQ1, PSA7B_XENLA;
DR   Q8TAA3, PSA7L_HUMAN;  Q4R7D9, PSA7L_MACFA;  Q9CWH6, PSA7L_MOUSE;
DR   Q3ZBG0, PSA7_BOVIN ;  Q95005, PSA7_CAEEL ;  Q9PTW9, PSA7_CARAU ;
DR   O13268, PSA7_CHICK ;  Q9SXU1, PSA7_CICAR ;  P34120, PSA7_DICDI ;
DR   O14818, PSA7_HUMAN ;  Q9Z2U0, PSA7_MOUSE ;  Q5RDH8, PSA7_PONAB ;
DR   P48004, PSA7_RAT   ;  Q10329, PSA7_SCHPO ;  O24030, PSA7_SOLLC ;
DR   Q9NDA2, PSA7_TRYBB ;  P40303, PSA7_YEAST ;  A0LU51, PSA_ACIC1  ;
DR   C7LYP8, PSA_ACIFD  ;  C6WID9, PSA_ACTMD  ;  Q9YC01, PSA_AERPE  ;
DR   O29760, PSA_ARCFU  ;  A1R6Q8, PSA_ARTAT  ;  B8H8L7, PSA_ARTCA  ;
DR   A0JWY7, PSA_ARTS2  ;  C7PVV3, PSA_CATAD  ;  Q0RLT6, PSA_FRAAA  ;
DR   Q2J9Q4, PSA_FRASC  ;  A8LH53, PSA_FRASN  ;  D2S6E3, PSA_GEOOG  ;
DR   D0LDT2, PSA_GORB4  ;  B0R2T2, PSA_HALS3  ;  P57697, PSA_HALSA  ;
DR   Q18K08, PSA_HALWD  ;  C7R404, PSA_JONDD  ;  A6W971, PSA_KINRD  ;
DR   D2Q4H5, PSA_KRIFD  ;  Q8TPX5, PSA_METAC  ;  A7I9C7, PSA_METB6  ;
DR   Q469M6, PSA_METBF  ;  Q60177, PSA_METJA  ;  Q8TYB7, PSA_METKA  ;
DR   A4FZT6, PSA_METM5  ;  A9A846, PSA_METM6  ;  A6VIP0, PSA_METM7  ;
DR   Q8PTU1, PSA_METMA  ;  A3CW55, PSA_METMJ  ;  Q6M0L9, PSA_METMP  ;
DR   B8GEZ3, PSA_METPE  ;  A5UJS2, PSA_METS3  ;  A4YCU9, PSA_METS5  ;
DR   Q59565, PSA_METTE  ;  O26782, PSA_METTH  ;  A6URN9, PSA_METVS  ;
DR   A0QFB6, PSA_MYCA1  ;  B1MAI3, PSA_MYCA9  ;  Q7TZ14, PSA_MYCBO  ;
DR   A1KKF2, PSA_MYCBP  ;  C1AQ25, PSA_MYCBT  ;  A4TB55, PSA_MYCGI  ;
DR   B8ZRF4, PSA_MYCLB  ;  Q9S375, PSA_MYCLE  ;  B2HFV5, PSA_MYCMM  ;
DR   Q73YW9, PSA_MYCPA  ;  A0QZ46, PSA_MYCS2  ;  A3Q192, PSA_MYCSJ  ;
DR   A1UHS6, PSA_MYCSK  ;  Q1B798, PSA_MYCSS  ;  A5U4D5, PSA_MYCTA  ;
DR   A5WP83, PSA_MYCTF  ;  C6DPV2, PSA_MYCTK  ;  O33244, PSA_MYCTU  ;
DR   A0PQT2, PSA_MYCUA  ;  A1TAP3, PSA_MYCVP  ;  C8XAQ3, PSA_NAKMY  ;
DR   Q3IPJ1, PSA_NATPD  ;  Q5YUX3, PSA_NOCFA  ;  A1SK14, PSA_NOCSJ  ;
DR   Q6L0W3, PSA_PICTO  ;  Q9V122, PSA_PYRAB  ;  Q8ZVM1, PSA_PYRAE  ;
DR   Q8U0L6, PSA_PYRFU  ;  O59219, PSA_PYRHO  ;  Q5JIU9, PSA_PYRKO  ;
DR   A9WSI0, PSA_RENSM  ;  C0ZZU6, PSA_RHOE4  ;  C1ASP6, PSA_RHOOB  ;
DR   Q0SIG0, PSA_RHOSR  ;  A4FBY2, PSA_SACEN  ;  C7MWV6, PSA_SACVD  ;
DR   A8M2A4, PSA_SALAI  ;  A4X745, PSA_SALTO  ;  D1BHT8, PSA_SANKS  ;
DR   D3Q556, PSA_STANL  ;  Q828I7, PSA_STRAW  ;  Q7AKQ6, PSA_STRCO  ;
DR   B1W307, PSA_STRGG  ;  D2ATV0, PSA_STRRD  ;  C9Z4D1, PSA_STRSW  ;
DR   Q4JB24, PSA_SULAC  ;  C3N5R0, PSA_SULIA  ;  C4KHD9, PSA_SULIK  ;
DR   C3MQ43, PSA_SULIL  ;  C3MVG1, PSA_SULIM  ;  C3NHC6, PSA_SULIN  ;
DR   C3NEC6, PSA_SULIY  ;  Q9UXC6, PSA_SULSO  ;  Q975G5, PSA_SULTO  ;
DR   P25156, PSA_THEAC  ;  D1A2T0, PSA_THECD  ;  Q47NZ5, PSA_THEFY  ;
DR   C5A2C2, PSA_THEGJ  ;  O24733, PSA_THEK1  ;  B6YSH9, PSA_THEON  ;
DR   C6A459, PSA_THESM  ;  Q97BZ8, PSA_THEVO  ;  D1BS27, PSA_XYLCX  ;
DR   Q3T0T1, PSB10_BOVIN;  P40306, PSB10_HUMAN;  O35955, PSB10_MOUSE;
DR   Q4KM35, PSB10_RAT  ;  A5LHX3, PSB11_HUMAN;  Q8BG41, PSB11_MOUSE;
DR   Q9IB84, PSB1A_CARAU;  Q9IB83, PSB1B_CARAU;  Q9YES4, PSB1_AERPE ;
DR   P42742, PSB1_ARATH ;  Q2TBX6, PSB1_BOVIN ;  P34286, PSB1_CAEEL ;
DR   A8MBW0, PSB1_CALMQ ;  A0RU86, PSB1_CENSY ;  B8D673, PSB1_DESK1 ;
DR   Q86A21, PSB1_DICDI ;  P40304, PSB1_DROME ;  Q8SRH6, PSB1_ENCCU ;
DR   Q5V4S6, PSB1_HALMA ;  D2RQX3, PSB1_HALTV ;  P20618, PSB1_HUMAN ;
DR   A2BN24, PSB1_HYPBU ;  A8AA46, PSB1_IGNH4 ;  B1L6S7, PSB1_KORCO ;
DR   A4YIE0, PSB1_METS5 ;  O09061, PSB1_MOUSE ;  A9A4A1, PSB1_NITMS ;
DR   O64464, PSB1_ORYSJ ;  O82531, PSB1_PETHY ;  Q9V247, PSB1_PYRAB ;
DR   Q8ZYF2, PSB1_PYRAE ;  A4WH05, PSB1_PYRAR ;  A3MS44, PSB1_PYRCJ ;
DR   Q8U4C9, PSB1_PYRFU ;  O57983, PSB1_PYRHO ;  A1RSJ8, PSB1_PYRIL ;
DR   Q5JDJ9, PSB1_PYRKO ;  P18421, PSB1_RAT   ;  Q53079, PSB1_RHOER ;
DR   A4X3P0, PSB1_SALTO ;  Q9UQY2, PSB1_SCHPO ;  A3DN21, PSB1_STAMF ;
DR   Q82JE3, PSB1_STRAW ;  Q4JAY3, PSB1_SULAC ;  C3N5N4, PSB1_SULIA ;
DR   D2PK63, PSB1_SULID ;  C4KHB0, PSB1_SULIK ;  C3MQ16, PSB1_SULIL ;
DR   C3MVD5, PSB1_SULIM ;  C3NFX2, PSB1_SULIN ;  C3NE98, PSB1_SULIY ;
DR   D0KRX1, PSB1_SULS9 ;  Q980L4, PSB1_SULSO ;  Q975U8, PSB1_SULTO ;
DR   D1A2S9, PSB1_THECD ;  C5A7L1, PSB1_THEGJ ;  B1YA36, PSB1_THENV ;
DR   B6YSW2, PSB1_THEON ;  A1RWY6, PSB1_THEPD ;  C6A2V9, PSB1_THESM ;
DR   Q9U794, PSB1_TRYBB ;  P23724, PSB1_YEAST ;  O23714, PSB2A_ARATH;
DR   O24633, PSB2B_ARATH;  Q9YER0, PSB2_AERPE ;  Q5E9K0, PSB2_BOVIN ;
DR   P91477, PSB2_CAEEL ;  A8M8R5, PSB2_CALMQ ;  A0RXV1, PSB2_CENSY ;
DR   P0CQ13, PSB2_CRYNB ;  P0CQ12, PSB2_CRYNJ ;  B8D683, PSB2_DESK1 ;
DR   Q55DY7, PSB2_DICDI ;  Q9VQE5, PSB2_DROME ;  Q8SRF1, PSB2_ENCCU ;
DR   Q5V1D5, PSB2_HALMA ;  D2RUI0, PSB2_HALTV ;  P49721, PSB2_HUMAN ;
DR   A2BN27, PSB2_HYPBU ;  A8AB58, PSB2_IGNH4 ;  B1L6X8, PSB2_KORCO ;
DR   A4YJ04, PSB2_METS5 ;  Q9R1P3, PSB2_MOUSE ;  Q9P6U7, PSB2_NEUCR ;
DR   A9A2U7, PSB2_NITMS ;  Q9LST6, PSB2_ORYSJ ;  A5DB52, PSB2_PICGU ;
DR   Q9V0N9, PSB2_PYRAB ;  Q8ZST5, PSB2_PYRAE ;  A4WMZ0, PSB2_PYRAR ;
DR   A3MXQ6, PSB2_PYRCJ ;  Q8U125, PSB2_PYRFU ;  O50110, PSB2_PYRHO ;
DR   A1RTI7, PSB2_PYRIL ;  Q5JHL8, PSB2_PYRKO ;  P40307, PSB2_RAT   ;
DR   Q53083, PSB2_RHOER ;  A4X744, PSB2_SALTO ;  Q09720, PSB2_SCHPO ;
DR   A3DN27, PSB2_STAMF ;  Q828I8, PSB2_STRAW ;  Q4JAA8, PSB2_SULAC ;
DR   C3MZI0, PSB2_SULIA ;  D2PDG6, PSB2_SULID ;  C4KIR0, PSB2_SULIK ;
DR   C3MRE5, PSB2_SULIL ;  C3MY41, PSB2_SULIM ;  C3NHF1, PSB2_SULIN ;
DR   C3N7K2, PSB2_SULIY ;  D0KTH0, PSB2_SULS9 ;  Q9UXF3, PSB2_SULSO ;
DR   Q975D1, PSB2_SULTO ;  D1A3V2, PSB2_THECD ;  C5A2D5, PSB2_THEGJ ;
DR   B1YDJ0, PSB2_THENV ;  B6YXV3, PSB2_THEON ;  A1RX71, PSB2_THEPD ;
DR   C6A3R1, PSB2_THESM ;  Q9NHC6, PSB2_TRYBB ;  P22141, PSB2_YEAST ;
DR   Q9XI05, PSB3A_ARATH;  O81153, PSB3B_ARATH;  P33672, PSB3_BOVIN ;
DR   Q23237, PSB3_CAEEL ;  Q55D66, PSB3_DICDI ;  Q9XYN7, PSB3_DROME ;
DR   Q9N9W8, PSB3_GIAIN ;  P49720, PSB3_HUMAN ;  Q9R1P1, PSB3_MOUSE ;
DR   O73817, PSB3_ONCMY ;  Q9LST7, PSB3_ORYSJ ;  O65084, PSB3_PICMA ;
DR   P40112, PSB3_RAT   ;  Q9Y7T8, PSB3_SCHPO ;  Q9NDA1, PSB3_TRYBB ;
DR   P25451, PSB3_YEAST ;  Q7DLR9, PSB4_ARATH ;  Q3T108, PSB4_BOVIN ;
DR   Q556Q0, PSB4_DICDI ;  Q9VNA5, PSB4_DROME ;  Q8SS01, PSB4_ENCCU ;
DR   P28070, PSB4_HUMAN ;  P99026, PSB4_MOUSE ;  Q29384, PSB4_PIG   ;
DR   P34067, PSB4_RAT   ;  Q9USQ9, PSB4_SCHPO ;  P28024, PSB4_XENLA ;
DR   P30657, PSB4_YEAST ;  O23717, PSB5A_ARATH;  Q9LIP2, PSB5B_ARATH;
DR   Q32KL2, PSB5_BOVIN ;  P34065, PSB5_CHICK ;  Q54BC8, PSB5_DICDI ;
DR   P28074, PSB5_HUMAN ;  O55234, PSB5_MOUSE ;  Q5R8S2, PSB5_PONAB ;
DR   P28075, PSB5_RAT   ;  P30655, PSB5_SCHPO ;  O24361, PSB5_SPIOL ;
DR   P30656, PSB5_YEAST ;  Q8LD27, PSB6_ARATH ;  Q3MHN0, PSB6_BOVIN ;
DR   Q55GJ6, PSB6_DICDI ;  Q8SR11, PSB6_ENCCU ;  P28072, PSB6_HUMAN ;
DR   Q60692, PSB6_MOUSE ;  P28073, PSB6_RAT   ;  O43063, PSB6_SCHPO ;
DR   P93395, PSB6_TOBAC ;  P38624, PSB6_YEAST ;  O23710, PSB7A_ARATH;
DR   Q7DLS1, PSB7B_ARATH;  Q2TBP0, PSB7_BOVIN ;  Q54QR2, PSB7_DICDI ;
DR   Q8SQN7, PSB7_ENCCU ;  Q99436, PSB7_HUMAN ;  P70195, PSB7_MOUSE ;
DR   A1XQU1, PSB7_PIG   ;  Q9JHW0, PSB7_RAT   ;  Q09841, PSB7_SCHPO ;
DR   P25043, PSB7_YEAST ;  Q3T112, PSB8_BOVIN ;  Q5W416, PSB8_CANFA ;
DR   P28062, PSB8_HUMAN ;  P28063, PSB8_MOUSE ;  Q29576, PSB8_PIG   ;
DR   P28064, PSB8_RAT   ;  Q3SZC2, PSB9_BOVIN ;  P28065, PSB9_HUMAN ;
DR   P28076, PSB9_MOUSE ;  O35521, PSB9_MUSDU ;  O35522, PSB9_MUSMB ;
DR   O35523, PSB9_MUSPL ;  O35524, PSB9_MUSSI ;  Q9PT26, PSB9_ONCMY ;
DR   Q8UW64, PSB9_ORYLA ;  P28077, PSB9_RAT   ;  Q9DD33, PSB9_SALSA ;
DR   B5IEE5, PSB_ACIB4  ;  A0LU50, PSB_ACIC1  ;  C7LYP7, PSB_ACIFD  ;
DR   C6WID8, PSB_ACTMD  ;  Q9P996, PSB_ARCFU  ;  D2RGT4, PSB_ARCPA  ;
DR   A1R6Q7, PSB_ARTAT  ;  B8H8L6, PSB_ARTCA  ;  A0JWY6, PSB_ARTS2  ;
DR   C5BVA2, PSB_BEUC1  ;  C7PVV2, PSB_CATAD  ;  D3RX66, PSB_FERPA  ;
DR   Q0RLT7, PSB_FRAAA  ;  Q2J9Q3, PSB_FRASC  ;  A8LH54, PSB_FRASN  ;
DR   D2S6E2, PSB_GEOOG  ;  D0LDT1, PSB_GORB4  ;  B9LTS6, PSB_HALLT  ;
DR   C7NVQ4, PSB_HALMD  ;  B0R4C8, PSB_HALS3  ;  Q9HR36, PSB_HALSA  ;
DR   C7NQ99, PSB_HALUD  ;  D4GYZ1, PSB_HALVD  ;  Q18GX3, PSB_HALWD  ;
DR   C7R403, PSB_JONDD  ;  A6W970, PSB_KINRD  ;  D2Q4H4, PSB_KRIFD  ;
DR   A6UT20, PSB_META3  ;  Q8TJB5, PSB_METAC  ;  A7I841, PSB_METB6  ;
DR   Q46G14, PSB_METBF  ;  Q12YV7, PSB_METBU  ;  C7P6N4, PSB_METFA  ;
DR   Q2FQL8, PSB_METHJ  ;  Q58634, PSB_METJA  ;  Q8TW10, PSB_METKA  ;
DR   A2SS78, PSB_METLZ  ;  A4FYA5, PSB_METM5  ;  A9A788, PSB_METM6  ;
DR   A6VK02, PSB_METM7  ;  Q8PZ04, PSB_METMA  ;  A3CUS9, PSB_METMJ  ;
DR   Q6LZD4, PSB_METMP  ;  D5EAS6, PSB_METMS  ;  B8GG66, PSB_METPE  ;
DR   D1Z199, PSB_METPS  ;  D3E0A3, PSB_METRM  ;  A5UM14, PSB_METS3  ;
DR   D3S8M7, PSB_METSF  ;  Q2NI68, PSB_METST  ;  Q9P992, PSB_METTE  ;
DR   O27270, PSB_METTH  ;  A0B5B1, PSB_METTP  ;  C9REN7, PSB_METVM  ;
DR   A6USJ3, PSB_METVS  ;  A0QFB5, PSB_MYCA1  ;  B1MAI2, PSB_MYCA9  ;
DR   Q7TZ13, PSB_MYCBO  ;  A1KKF3, PSB_MYCBP  ;  C1AQ26, PSB_MYCBT  ;
DR   A4TB64, PSB_MYCGI  ;  B8ZRF3, PSB_MYCLB  ;  Q49780, PSB_MYCLE  ;
DR   B2HFV6, PSB_MYCMM  ;  Q73YW8, PSB_MYCPA  ;  A0QZ47, PSB_MYCS2  ;
DR   A3Q193, PSB_MYCSJ  ;  A1UHS7, PSB_MYCSK  ;  Q1B797, PSB_MYCSS  ;
DR   A5U4D6, PSB_MYCTA  ;  A5WP84, PSB_MYCTF  ;  C6DPV1, PSB_MYCTK  ;
DR   O33245, PSB_MYCTU  ;  A0PQT3, PSB_MYCUA  ;  A1TAP4, PSB_MYCVP  ;
DR   C8XAQ4, PSB_NAKMY  ;  Q74MP5, PSB_NANEQ  ;  D3SSQ6, PSB_NATMM  ;
DR   Q3IPX1, PSB_NATPD  ;  Q5YUX2, PSB_NOCFA  ;  A1SK13, PSB_NOCSJ  ;
DR   Q6L181, PSB_PICTO  ;  A9WSI1, PSB_RENSM  ;  C0ZZU7, PSB_RHOE4  ;
DR   C1ASP7, PSB_RHOOB  ;  Q0SIF9, PSB_RHOSR  ;  A4FBY1, PSB_SACEN  ;
DR   C7MWV7, PSB_SACVD  ;  A8M2A3, PSB_SALAI  ;  D1BHT9, PSB_SANKS  ;
DR   D3Q557, PSB_STANL  ;  Q7AKQ5, PSB_STRCO  ;  B1W306, PSB_STRGG  ;
DR   D2ATV1, PSB_STRRD  ;  C9Z4D0, PSB_STRSW  ;  P28061, PSB_THEAC  ;
DR   Q47NZ4, PSB_THEFY  ;  Q97AZ7, PSB_THEVO  ;  Q0W2D6, PSB_UNCMA  ;
DR   D1BS26, PSB_XYLCX  ;  P84799, PSMA_HALDO ;
//
ID   3.4.25.2
DE   HslU--HslV peptidase.
CA   ATP-dependent cleavage of peptide bonds with broad specificity.
CC   -!- The HslU subunit of the HslU--HslV complex functions as an ATP
CC       dependent 'unfoldase'.
CC   -!- The binding of ATP and its subsequent hydrolysis by HslU are
CC       essential for unfolding of protein substrates subsequently hydrolyzed
CC       by HslV.
CC   -!- HslU recognizes the N-terminal part of its protein substrates and
CC       unfolds these before they are guided to HslV for hydrolysis.
CC   -!- Belongs to peptidase family T1.
DR   Q1IV81, HSLV_ACIBL ;  A5FYD8, HSLV_ACICJ ;  B9MFS3, HSLV_ACIET ;
DR   A3N334, HSLV_ACTP2 ;  B3GYW3, HSLV_ACTP7 ;  B0BSG5, HSLV_ACTPJ ;
DR   A6VL80, HSLV_ACTSZ ;  A0KQI7, HSLV_AERHH ;  A4SHM2, HSLV_AERS4 ;
DR   B9JG70, HSLV_AGRRK ;  Q8UJ88, HSLV_AGRT5 ;  B9JXW5, HSLV_AGRVS ;
DR   Q0VMA6, HSLV_ALCBS ;  Q0ACL4, HSLV_ALHEH ;  B3EU68, HSLV_AMOA5 ;
DR   B8JES1, HSLV_ANAD2 ;  Q2ILD4, HSLV_ANADE ;  A7HDU3, HSLV_ANADF ;
DR   Q5P9Z6, HSLV_ANAMM ;  Q2GJ25, HSLV_ANAPZ ;  B4UIH9, HSLV_ANASK ;
DR   B9MM31, HSLV_ANATD ;  B7GGC6, HSLV_ANOFW ;  O67587, HSLV_AQUAE ;
DR   A8ETF7, HSLV_ARCB4 ;  Q5P502, HSLV_AROAE ;  A1K2I5, HSLV_AZOSB ;
DR   C3P5N2, HSLV_BACAA ;  C3L797, HSLV_BACAC ;  A0RHK3, HSLV_BACAH ;
DR   Q81WK5, HSLV_BACAN ;  B7JJA8, HSLV_BACC0 ;  P61476, HSLV_BACC1 ;
DR   B7IUI9, HSLV_BACC2 ;  C1EP54, HSLV_BACC3 ;  B7HDV3, HSLV_BACC4 ;
DR   B7HLG3, HSLV_BACC7 ;  A7GRG0, HSLV_BACCN ;  B9IVB9, HSLV_BACCQ ;
DR   Q819X6, HSLV_BACCR ;  Q636J6, HSLV_BACCZ ;  Q9KA26, HSLV_BACHD ;
DR   Q6HEY5, HSLV_BACHK ;  Q5WFQ0, HSLV_BACSK ;  A9VT68, HSLV_BACWK ;
DR   Q6G5G1, HSLV_BARHE ;  Q6G0Q0, HSLV_BARQU ;  Q1LTT6, HSLV_BAUCH ;
DR   Q2L1C6, HSLV_BORA1 ;  Q0SNL5, HSLV_BORAP ;  Q7WQZ3, HSLV_BORBR ;
DR   Q57209, HSLV_BORBU ;  B7J1M4, HSLV_BORBZ ;  B5RLC2, HSLV_BORDL ;
DR   Q661W9, HSLV_BORGA ;  B2S007, HSLV_BORHD ;  Q7W215, HSLV_BORPA ;
DR   A9IH51, HSLV_BORPD ;  Q7VUK0, HSLV_BORPE ;  B5RRB6, HSLV_BORRA ;
DR   A1QZ92, HSLV_BORT9 ;  Q89WM9, HSLV_BRAJA ;  A5E8F2, HSLV_BRASB ;
DR   A4YJV0, HSLV_BRASO ;  C0ZFA7, HSLV_BREBN ;  B2S979, HSLV_BRUA1 ;
DR   Q2YQZ3, HSLV_BRUA2 ;  Q57AH8, HSLV_BRUAB ;  A9M9R4, HSLV_BRUC2 ;
DR   C0RFW8, HSLV_BRUMB ;  Q8YE31, HSLV_BRUME ;  A5VT38, HSLV_BRUO2 ;
DR   B0CJI0, HSLV_BRUSI ;  Q8FY11, HSLV_BRUSU ;  P57115, HSLV_BUCAI ;
DR   Q8K906, HSLV_BUCAP ;  P59581, HSLV_BUCBP ;  Q056X3, HSLV_BUCCC ;
DR   B1YPR2, HSLV_BURA4 ;  Q1BSM9, HSLV_BURCA ;  B1K0G1, HSLV_BURCC ;
DR   A0KBG2, HSLV_BURCH ;  B4E7Z2, HSLV_BURCJ ;  Q0BAX9, HSLV_BURCM ;
DR   A9AC32, HSLV_BURM1 ;  Q62EZ9, HSLV_BURMA ;  A3NQ63, HSLV_BURP0 ;
DR   B2JJX8, HSLV_BURP8 ;  B2T1N9, HSLV_BURPP ;  Q63YI3, HSLV_BURPS ;
DR   Q39BY1, HSLV_BURS3 ;  A4JIR2, HSLV_BURVG ;  Q146W9, HSLV_BURXL ;
DR   A4XIW9, HSLV_CALS8 ;  A7ZDF4, HSLV_CAMC1 ;  A7GYN6, HSLV_CAMC5 ;
DR   A0RPN4, HSLV_CAMFF ;  A7I279, HSLV_CAMHC ;  A8FL81, HSLV_CAMJ8 ;
DR   A7H4F1, HSLV_CAMJD ;  Q9PHK9, HSLV_CAMJE ;  A1VZ22, HSLV_CAMJJ ;
DR   Q5HVB1, HSLV_CAMJR ;  B9KG99, HSLV_CAMLR ;  Q3AB73, HSLV_CARHZ ;
DR   Q9A239, HSLV_CAUCR ;  B0T7B0, HSLV_CAUSK ;  B3PI66, HSLV_CELJU ;
DR   Q3ASH7, HSLV_CHLCH ;  B3ECB1, HSLV_CHLL2 ;  B3QNN5, HSLV_CHLP8 ;
DR   B3EJG6, HSLV_CHLPB ;  A1BGP1, HSLV_CHLPD ;  Q8KD62, HSLV_CHLTE ;
DR   Q7P113, HSLV_CHRVO ;  A9KH30, HSLV_COXBN ;  A9N9F9, HSLV_COXBR ;
DR   Q83A95, HSLV_COXBU ;  Q0KF70, HSLV_CUPNH ;  Q476Y4, HSLV_CUPPJ ;
DR   B2AGB6, HSLV_CUPTR ;  Q11UQ9, HSLV_CYTH3 ;  Q47JL9, HSLV_DECAR ;
DR   A9BUJ5, HSLV_DELAS ;  C6C0P0, HSLV_DESAD ;  B1I260, HSLV_DESAP ;
DR   B8J0S4, HSLV_DESDA ;  Q30ZH5, HSLV_DESDG ;  B8FRG9, HSLV_DESHD ;
DR   Q24UF3, HSLV_DESHY ;  C4XN25, HSLV_DESMR ;  A4J5Z6, HSLV_DESRM ;
DR   Q72BQ7, HSLV_DESVH ;  B8DKL3, HSLV_DESVM ;  A1VDQ7, HSLV_DESVV ;
DR   A5EX24, HSLV_DICNV ;  A8LPA8, HSLV_DINSH ;  A7ZUE7, HSLV_ECO24 ;
DR   B7UNQ2, HSLV_ECO27 ;  B7MI64, HSLV_ECO45 ;  B7LA29, HSLV_ECO55 ;
DR   P0A7C0, HSLV_ECO57 ;  B5YZ72, HSLV_ECO5E ;  B7NU73, HSLV_ECO7I ;
DR   B7MR21, HSLV_ECO81 ;  B7M6Y3, HSLV_ECO8A ;  C5A099, HSLV_ECOBW ;
DR   B1XB98, HSLV_ECODH ;  A8A738, HSLV_ECOHS ;  A1AIA7, HSLV_ECOK1 ;
DR   Q0TAD2, HSLV_ECOL5 ;  P0A7B9, HSLV_ECOL6 ;  B1IVE7, HSLV_ECOLC ;
DR   P0A7B8, HSLV_ECOLI ;  B7NFN1, HSLV_ECOLU ;  B6I4S5, HSLV_ECOSE ;
DR   B1LNN7, HSLV_ECOSM ;  Q1R3Y5, HSLV_ECOUT ;  Q3YR20, HSLV_EHRCJ ;
DR   Q2GFK0, HSLV_EHRCR ;  Q5FGD0, HSLV_EHRRG ;  Q5HAB3, HSLV_EHRRW ;
DR   A4WG66, HSLV_ENT38 ;  Q834K3, HSLV_ENTFA ;  Q6CZ92, HSLV_ERWCT ;
DR   B2VF49, HSLV_ERWT9 ;  B7LUS2, HSLV_ESCF3 ;  C1ABE1, HSLV_GEMAT ;
DR   Q5L0N2, HSLV_GEOKA ;  C5D8V8, HSLV_GEOSW ;  A4IM88, HSLV_GEOTN ;
DR   Q7VKB4, HSLV_HAEDU ;  Q4QN50, HSLV_HAEI8 ;  A5U9Z6, HSLV_HAEIE ;
DR   A5UH05, HSLV_HAEIG ;  P43772, HSLV_HAEIN ;  B8F689, HSLV_HAEPS ;
DR   Q0I5E1, HSLV_HAES1 ;  B0US06, HSLV_HAES2 ;  Q2S9P4, HSLV_HAHCH ;
DR   A1WWB6, HSLV_HALHL ;  C4K5T1, HSLV_HAMD5 ;  Q17XG1, HSLV_HELAH ;
DR   Q7VJD3, HSLV_HELHP ;  B6JL97, HSLV_HELP2 ;  B5Z6N8, HSLV_HELPG ;
DR   Q1CU16, HSLV_HELPH ;  Q9ZLW2, HSLV_HELPJ ;  B2UTX3, HSLV_HELPS ;
DR   O25253, HSLV_HELPY ;  A4G989, HSLV_HERAR ;  Q0C0L2, HSLV_HYPNA ;
DR   Q5QV35, HSLV_IDILO ;  A6T306, HSLV_JANMA ;  Q28W10, HSLV_JANSC ;
DR   B5XZ36, HSLV_KLEP3 ;  A6TGC2, HSLV_KLEP7 ;  Q039E0, HSLV_LACC3 ;
DR   B3WEA8, HSLV_LACCB ;  Q48734, HSLV_LACLE ;  Q88W25, HSLV_LACPL ;
DR   Q1WTI9, HSLV_LACS1 ;  Q1MQE1, HSLV_LAWIP ;  Q5X7B1, HSLV_LEGPA ;
DR   A5IGR7, HSLV_LEGPC ;  Q5ZXU1, HSLV_LEGPH ;  Q5WYQ9, HSLV_LEGPL ;
DR   B0SCD1, HSLV_LEPBA ;  Q04TA2, HSLV_LEPBJ ;  Q051M4, HSLV_LEPBL ;
DR   Q8GQU1, HSLV_LEPBO ;  B0SKV3, HSLV_LEPBP ;  B1Y6R3, HSLV_LEPCP ;
DR   Q72RY8, HSLV_LEPIC ;  Q8F3Q4, HSLV_LEPIN ;  Q92C74, HSLV_LISIN ;
DR   C1L2I6, HSLV_LISMC ;  Q720E3, HSLV_LISMF ;  B8DG53, HSLV_LISMH ;
DR   Q8Y7J9, HSLV_LISMO ;  A0AI81, HSLV_LISW6 ;  B1HQJ5, HSLV_LYSSC ;
DR   B9EBD3, HSLV_MACCJ ;  Q2VYI5, HSLV_MAGSA ;  A0L3K3, HSLV_MAGSM ;
DR   Q65VY2, HSLV_MANSM ;  A1TYU6, HSLV_MARAV ;  A6W2U5, HSLV_MARMS ;
DR   Q11CL2, HSLV_MESSB ;  B7KZ47, HSLV_METC4 ;  Q606K2, HSLV_METCA ;
DR   A9W0F2, HSLV_METEP ;  A2SLA3, HSLV_METPP ;  Q2RJP6, HSLV_MOOTA ;
DR   Q84F94, HSLV_MYXXA ;  Q1D802, HSLV_MYXXD ;  Q2GEM5, HSLV_NEOSM ;
DR   Q0AD36, HSLV_NITEC ;  Q82SP7, HSLV_NITEU ;  Q1QRX5, HSLV_NITHX ;
DR   Q3J8P8, HSLV_NITOC ;  A6Q3Q1, HSLV_NITSB ;  Q3SWE6, HSLV_NITWN ;
DR   Q8CXH2, HSLV_OCEIH ;  A6WX57, HSLV_OCHA4 ;  B6JAL5, HSLV_OLICO ;
DR   A1B5T1, HSLV_PARDP ;  A7HSH6, HSLV_PARL1 ;  P49617, HSLV_PASHA ;
DR   P57969, HSLV_PASMU ;  C6DHM7, HSLV_PECCP ;  Q03FK3, HSLV_PEDPA ;
DR   Q3A1V7, HSLV_PELCD ;  Q3B4D9, HSLV_PELLD ;  B4SGR7, HSLV_PELPB ;
DR   A5D2W7, HSLV_PELTS ;  C0QS72, HSLV_PERMH ;  A9BI45, HSLV_PETMO ;
DR   Q7MYC2, HSLV_PHOLL ;  Q6LVI2, HSLV_PHOPR ;  B4S817, HSLV_PROA2 ;
DR   B4F172, HSLV_PROMH ;  A4SER5, HSLV_PROVI ;  Q48PI4, HSLV_PSE14 ;
DR   Q15N48, HSLV_PSEA6 ;  A6VDH4, HSLV_PSEA7 ;  B7V3E6, HSLV_PSEA8 ;
DR   Q02EW4, HSLV_PSEAB ;  Q9HUC6, HSLV_PSEAE ;  Q1I3U0, HSLV_PSEE4 ;
DR   Q4KJK2, HSLV_PSEF5 ;  C3KAH1, HSLV_PSEFS ;  A4XPN7, HSLV_PSEMY ;
DR   Q88D28, HSLV_PSEPK ;  Q87V01, HSLV_PSESM ;  A1SQW4, HSLV_PSYIN ;
DR   Q1LS59, HSLV_RALME ;  B2U7X2, HSLV_RALPJ ;  Q8Y3D7, HSLV_RALSO ;
DR   B3PWI6, HSLV_RHIE6 ;  Q2KE55, HSLV_RHIEC ;  Q1MNB5, HSLV_RHIL3 ;
DR   Q98CT8, HSLV_RHILO ;  B5ZV98, HSLV_RHILW ;  Q92TA9, HSLV_RHIME ;
DR   C3MBC6, HSLV_RHISN ;  Q21SV8, HSLV_RHOFD ;  P61477, HSLV_RHOPA ;
DR   A3PG34, HSLV_RHOS1 ;  Q3J6B2, HSLV_RHOS4 ;  A4WWS1, HSLV_RHOS5 ;
DR   B9KRG9, HSLV_RHOSK ;  C3PN29, HSLV_RICAE ;  A8GMZ9, HSLV_RICAH ;
DR   A8GWX0, HSLV_RICB8 ;  Q1RIB6, HSLV_RICBR ;  A8EZD3, HSLV_RICCK ;
DR   Q92II7, HSLV_RICCN ;  Q4UM54, HSLV_RICFE ;  Q9ZDK9, HSLV_RICPR ;
DR   C4K1X3, HSLV_RICPU ;  B0BX21, HSLV_RICRO ;  A8GRL7, HSLV_RICRS ;
DR   Q68X53, HSLV_RICTY ;  Q16CY0, HSLV_ROSDO ;  Q21H72, HSLV_SACD2 ;
DR   B5F0S3, HSLV_SALA4 ;  Q57HC5, HSLV_SALCH ;  B5FPU1, HSLV_SALDC ;
DR   B5QXM1, HSLV_SALEP ;  B5RF79, HSLV_SALG2 ;  B4TCM9, HSLV_SALHS ;
DR   B4T0T9, HSLV_SALNS ;  Q5PK45, HSLV_SALPA ;  A9MZI2, HSLV_SALPB ;
DR   C0Q442, HSLV_SALPC ;  B5BJK9, HSLV_SALPK ;  B4TPV3, HSLV_SALSV ;
DR   P0A272, HSLV_SALTI ;  P0A271, HSLV_SALTY ;  A8GL95, HSLV_SERP5 ;
DR   A1S2P5, HSLV_SHEAM ;  B8E6E4, HSLV_SHEB2 ;  A3D9C5, HSLV_SHEB5 ;
DR   A6WIH6, HSLV_SHEB8 ;  A9KYP9, HSLV_SHEB9 ;  Q12IT9, HSLV_SHEDO ;
DR   Q07WM3, HSLV_SHEFN ;  B0TVV3, HSLV_SHEHH ;  A3Q9U9, HSLV_SHELP ;
DR   Q8E9V0, HSLV_SHEON ;  A8H955, HSLV_SHEPA ;  A4Y2S8, HSLV_SHEPC ;
DR   B8CI19, HSLV_SHEPW ;  A0L1J8, HSLV_SHESA ;  A8FQM0, HSLV_SHESH ;
DR   Q0HED1, HSLV_SHESM ;  Q0HZL8, HSLV_SHESR ;  B1KK50, HSLV_SHEWM ;
DR   B2TWC8, HSLV_SHIB3 ;  Q31U58, HSLV_SHIBS ;  Q32AA5, HSLV_SHIDS ;
DR   Q0SY57, HSLV_SHIF8 ;  P0A7C1, HSLV_SHIFL ;  Q3YV46, HSLV_SHISS ;
DR   Q5LLP2, HSLV_SILPO ;  Q1GCN5, HSLV_SILST ;  A6UEK8, HSLV_SINMW ;
DR   Q2NQY2, HSLV_SODGM ;  Q01Q19, HSLV_SOLUE ;  A5VEJ8, HSLV_SPHWW ;
DR   A7X1M9, HSLV_STAA1 ;  A6U171, HSLV_STAA2 ;  Q2FHI5, HSLV_STAA3 ;
DR   Q2FZ29, HSLV_STAA8 ;  A5ISD7, HSLV_STAA9 ;  Q2YXL5, HSLV_STAAB ;
DR   Q5HGH9, HSLV_STAAC ;  A6QGF3, HSLV_STAAE ;  P65796, HSLV_STAAM ;
DR   P65797, HSLV_STAAN ;  Q6GHI2, HSLV_STAAR ;  Q6G9W0, HSLV_STAAS ;
DR   A8Z3T3, HSLV_STAAT ;  P65798, HSLV_STAAW ;  B9DPG5, HSLV_STACT ;
DR   Q5HPT9, HSLV_STAEQ ;  Q8CPH1, HSLV_STAES ;  Q4L5V5, HSLV_STAHJ ;
DR   Q49X38, HSLV_STAS1 ;  B4SJN0, HSLV_STRM5 ;  B2FUV7, HSLV_STRMK ;
DR   Q30QS8, HSLV_SULDN ;  A6QAX2, HSLV_SULNB ;  B2V939, HSLV_SULSY ;
DR   A0LEB7, HSLV_SYNFM ;  Q0AYP2, HSLV_SYNWW ;  C5BRK9, HSLV_TERTT ;
DR   B7IFU1, HSLV_THEAB ;  A8F5A7, HSLV_THELT ;  A6LJK3, HSLV_THEM4 ;
DR   Q9WYZ1, HSLV_THEMA ;  A5IJQ3, HSLV_THEP1 ;  B0K9V4, HSLV_THEP3 ;
DR   B0K1T7, HSLV_THEPX ;  B1L8X4, HSLV_THESQ ;  Q8R9Y2, HSLV_THETN ;
DR   B5YFZ9, HSLV_THEYD ;  Q31IL7, HSLV_THICR ;  Q3SFW2, HSLV_THIDA ;
DR   B8GTA0, HSLV_THISH ;  C4L9X0, HSLV_TOLAT ;  P61478, HSLV_TREDE ;
DR   C5CNE3, HSLV_VARPS ;  A1WRK0, HSLV_VEREI ;  A5F4X4, HSLV_VIBC3 ;
DR   Q9KNQ6, HSLV_VIBCH ;  C3LSA4, HSLV_VIBCM ;  B5FBL7, HSLV_VIBFM ;
DR   A7MWJ4, HSLV_VIBHB ;  Q87T20, HSLV_VIBPA ;  B7VLM6, HSLV_VIBSL ;
DR   Q8DCP3, HSLV_VIBVU ;  Q7MH57, HSLV_VIBVY ;  Q8D2S6, HSLV_WIGBR ;
DR   P61479, HSLV_WOLPM ;  B3CLU4, HSLV_WOLPP ;  Q7M8Z6, HSLV_WOLSU ;
DR   Q5GRR4, HSLV_WOLTR ;  C0R4L3, HSLV_WOLWR ;  Q8PPP8, HSLV_XANAC ;
DR   Q3BXU0, HSLV_XANC5 ;  Q4UYX7, HSLV_XANC8 ;  Q8P551, HSLV_XANCP ;
DR   Q2NYV8, HSLV_XANOM ;  B2IA19, HSLV_XYLF2 ;  P65799, HSLV_XYLFA ;
DR   P65800, HSLV_XYLFT ;  A1JI09, HSLV_YERE8 ;  A7FCY5, HSLV_YERP3 ;
DR   Q1CBE7, HSLV_YERPA ;  B2JZC6, HSLV_YERPB ;  Q8ZJJ4, HSLV_YERPE ;
DR   A9R6C8, HSLV_YERPG ;  Q1CD56, HSLV_YERPN ;  A4TS83, HSLV_YERPP ;
DR   Q66G84, HSLV_YERPS ;  B1JQ75, HSLV_YERPY ;  Q5NQY4, HSLV_ZYMMO ;
//
ID   3.4.99.1
DE   Transferred entry: 3.4.23.28.
//
ID   3.4.99.2
DE   Deleted entry.
//
ID   3.4.99.3
DE   Deleted entry.
//
ID   3.4.99.4
DE   Transferred entry: 3.4.23.12.
//
ID   3.4.99.5
DE   Transferred entry: 3.4.24.3.
//
ID   3.4.99.6
DE   Transferred entry: 3.4.24.21.
//
ID   3.4.99.7
DE   Deleted entry.
//
ID   3.4.99.8
DE   Deleted entry.
//
ID   3.4.99.9
DE   Deleted entry.
//
ID   3.4.99.10
DE   Transferred entry: 3.4.24.56.
//
ID   3.4.99.11
DE   Deleted entry.
//
ID   3.4.99.12
DE   Deleted entry.
//
ID   3.4.99.13
DE   Transferred entry: 3.4.24.32.
//
ID   3.4.99.14
DE   Deleted entry.
//
ID   3.4.99.15
DE   Deleted entry.
//
ID   3.4.99.16
DE   Deleted entry.
//
ID   3.4.99.17
DE   Deleted entry.
//
ID   3.4.99.18
DE   Deleted entry.
//
ID   3.4.99.19
DE   Transferred entry: 3.4.23.15.
//
ID   3.4.99.20
DE   Deleted entry.
//
ID   3.4.99.21
DE   Deleted entry.
//
ID   3.4.99.22
DE   Transferred entry: 3.4.24.29.
//
ID   3.4.99.23
DE   Deleted entry.
//
ID   3.4.99.24
DE   Deleted entry.
//
ID   3.4.99.25
DE   Transferred entry: 3.4.23.21.
//
ID   3.4.99.26
DE   Transferred entry: 3.4.21.68 and 3.4.21.73.
//
ID   3.4.99.27
DE   Deleted entry.
//
ID   3.4.99.28
DE   Transferred entry: 3.4.21.60.
//
ID   3.4.99.29
DE   Deleted entry.
//
ID   3.4.99.30
DE   Transferred entry: 3.4.24.20.
//
ID   3.4.99.31
DE   Transferred entry: 3.4.24.15.
//
ID   3.4.99.32
DE   Transferred entry: 3.4.24.20.
//
ID   3.4.99.33
DE   Deleted entry.
//
ID   3.4.99.34
DE   Deleted entry.
//
ID   3.4.99.35
DE   Transferred entry: 3.4.23.36.
//
ID   3.4.99.36
DE   Transferred entry: 3.4.21.89.
//
ID   3.4.99.37
DE   Deleted entry.
//
ID   3.4.99.38
DE   Transferred entry: 3.4.23.17.
//
ID   3.4.99.39
DE   Deleted entry.
//
ID   3.4.99.40
DE   Deleted entry.
//
ID   3.4.99.41
DE   Transferred entry: 3.4.24.64.
//
ID   3.4.99.42
DE   Deleted entry.
//
ID   3.4.99.43
DE   Transferred entry: 3.4.23.42.
//
ID   3.4.99.44
DE   Transferred entry: 3.4.24.55.
//
ID   3.4.99.45
DE   Transferred entry: 3.4.24.56.
//
ID   3.4.99.46
DE   Transferred entry: 3.4.25.1.
//
ID   3.5.1.1
DE   Asparaginase.
AN   L-asparaginase.
AN   L-asparagine amidohydrolase.
CA   L-asparagine + H(2)O = L-aspartate + NH(3).
PR   PROSITE; PDOC00132;
DR   Q32LE5, ASGL1_BOVIN;  Q5BKW9, ASGL1_DANRE;  Q9VXT7, ASGL1_DROME;
DR   Q29I93, ASGL1_DROPS;  Q7L266, ASGL1_HUMAN;  Q4R7U8, ASGL1_MACFA;
DR   Q8C0M9, ASGL1_MOUSE;  Q8VI04, ASGL1_RAT  ;  Q6GM78, ASGL1_XENLA;
DR   Q9V262, ASGX_PYRAB ;  Q8U4E6, ASGX_PYRFU ;  O57971, ASGX_PYRHO ;
DR   Q5JHT1, ASGX_PYRKO ;  P0CZ17, ASP21_YEAST;  P0CX77, ASP22_YEAST;
DR   P0CX78, ASP23_YEAST;  P0CX79, ASP24_YEAST;  P26900, ASPG1_BACSU;
DR   P0A963, ASPG1_ECO57;  P0A962, ASPG1_ECOLI;  P87015, ASPG1_SCHPO;
DR   P38986, ASPG1_YEAST;  O34482, ASPG2_BACSU;  P00805, ASPG2_ECOLI;
DR   P43843, ASPG2_HAEIN;  Q9UTS7, ASPG2_SCHPO;  Q8NKC0, ASPG3_SCHPO;
DR   Q8TFF8, ASPG4_SCHPO;  Q9P6N7, ASPGX_SCHPO;  P30363, ASPG_BACLI ;
DR   Q9RRX9, ASPG_DEIRA ;  Q9U518, ASPG_DIRIM ;  P06608, ASPG_ERWCH ;
DR   Q9ZLB9, ASPG_HELPJ ;  O25424, ASPG_HELPY ;  P63628, ASPG_MYCBO ;
DR   Q9X7E6, ASPG_MYCLE ;  P63627, ASPG_MYCTU ;  P50286, ASPG_WOLSU ;
DR   Q86U10, LPP60_HUMAN;  A0JNU3, LPP60_MOUSE;  O88202, LPP60_RAT  ;
//
ID   3.5.1.2
DE   Glutaminase.
AN   L-glutamine amidohydrolase.
CA   L-glutamine + H(2)O = L-glutamate + NH(3).
PR   PROSITE; PDOC00132;
DR   Q19013, GLS1_CAEEL ;  Q93650, GLS2_CAEEL ;  Q81YY0, GLSA1_BACAN;
DR   Q81IB3, GLSA1_BACCR;  Q9K9L8, GLSA1_BACHD;  O31465, GLSA1_BACSU;
DR   Q89NA7, GLSA1_BRAJA;  Q8XMU7, GLSA1_CLOPE;  Q8XD23, GLSA1_ECO57;
DR   Q8FK76, GLSA1_ECOL6;  P77454, GLSA1_ECOLI;  Q83SE1, GLSA1_SHIFL;
DR   Q8ZHF1, GLSA1_YERPE;  Q81NN0, GLSA2_BACAN;  Q81BN7, GLSA2_BACCR;
DR   Q9K9D1, GLSA2_BACHD;  O07637, GLSA2_BACSU;  Q89KV2, GLSA2_BRAJA;
DR   Q8XIW8, GLSA2_CLOPE;  P0A6W2, GLSA2_ECO57;  P0A6W1, GLSA2_ECOL6;
DR   P0A6W0, GLSA2_ECOLI;  Q83RE2, GLSA2_SHIFL;  Q9ZC49, GLSA2_YERPE;
DR   B0C9Y4, GLSA_ACAM1 ;  A0KNV3, GLSA_AERHH ;  A4SJB3, GLSA_AERS4 ;
DR   B9JFR4, GLSA_AGRRK ;  Q8UEA1, GLSA_AGRT5 ;  B2UL96, GLSA_AKKM8 ;
DR   B6EMU2, GLSA_ALISL ;  A6TU96, GLSA_ALKMQ ;  A8MIB3, GLSA_ALKOO ;
DR   Q3MEJ6, GLSA_ANAVT ;  A8EX66, GLSA_ARCB4 ;  A8IEU9, GLSA_AZOC5 ;
DR   Q73E07, GLSA_BACC1 ;  C1EWD5, GLSA_BACC3 ;  A7GKX3, GLSA_BACCN ;
DR   Q5LI65, GLSA_BACFN ;  Q64Z72, GLSA_BACFR ;  Q5WL84, GLSA_BACSK ;
DR   Q8A4M8, GLSA_BACTN ;  A9VSP6, GLSA_BACWK ;  Q2KVV8, GLSA_BORA1 ;
DR   B2SBQ3, GLSA_BRUA1 ;  Q2YK17, GLSA_BRUA2 ;  Q577F0, GLSA_BRUAB ;
DR   A9ME88, GLSA_BRUC2 ;  A9WY35, GLSA_BRUSI ;  Q8FWV5, GLSA_BRUSU ;
DR   B2TG13, GLSA_BURPP ;  B8GYE8, GLSA_CAUCN ;  Q9ABF2, GLSA_CAUCR ;
DR   Q7NQH9, GLSA_CHRVO ;  A8AGR2, GLSA_CITK8 ;  A5CLW1, GLSA_CLAM3 ;
DR   A7FX54, GLSA_CLOB1 ;  C3L2L2, GLSA_CLOB6 ;  A5I5P4, GLSA_CLOBH ;
DR   C1FUY9, GLSA_CLOBJ ;  B1IKM0, GLSA_CLOBK ;  A7GH26, GLSA_CLOBL ;
DR   B1KYY3, GLSA_CLOBM ;  Q189A6, GLSA_CLOD6 ;  Q898A3, GLSA_CLOTE ;
DR   Q47UZ9, GLSA_COLP3 ;  Q8FMX4, GLSA_COREF ;  Q8NMT3, GLSA_CORGL ;
DR   Q11UA6, GLSA_CYTH3 ;  B8J1X3, GLSA_DESDA ;  B7MQK2, GLSA_ECO81 ;
DR   A4WAF3, GLSA_ENT38 ;  A7MPS3, GLSA_ENTS8 ;  C4L2C1, GLSA_EXISA ;
DR   Q8RDV3, GLSA_FUSNN ;  Q5KY26, GLSA_GEOKA ;  A4IPX2, GLSA_GEOTN ;
DR   Q5FP94, GLSA_GLUOX ;  A0M4Z1, GLSA_GRAFK ;  Q2S6X2, GLSA_HAHCH ;
DR   B5XQU9, GLSA_KLEP3 ;  A6T8Z6, GLSA_KLEP7 ;  Q5X8E2, GLSA_LEGPA ;
DR   A5IAB4, GLSA_LEGPC ;  Q5ZYX0, GLSA_LEGPH ;  Q5WZT6, GLSA_LEGPL ;
DR   A6W1W5, GLSA_MARMS ;  B7KNQ3, GLSA_METC4 ;  A9W5B4, GLSA_METEP ;
DR   B8ICY0, GLSA_METNO ;  B1Z987, GLSA_METPB ;  B1LUS0, GLSA_METRJ ;
DR   B0UQS5, GLSA_METS4 ;  B0JPM4, GLSA_MICAN ;  B2HGL4, GLSA_MYCMM ;
DR   A0PTH3, GLSA_MYCUA ;  B2A4X5, GLSA_NATTJ ;  Q8YSZ5, GLSA_NOSS1 ;
DR   Q8CV87, GLSA_OCEIH ;  A6LA76, GLSA_PARD8 ;  Q7N7H7, GLSA_PHOLL ;
DR   Q6LML1, GLSA_PHOPR ;  B4EUR1, GLSA_PROMH ;  Q48HR7, GLSA_PSE14 ;
DR   Q15U72, GLSA_PSEA6 ;  A6V7F4, GLSA_PSEA7 ;  B7UV83, GLSA_PSEA8 ;
DR   Q02KC3, GLSA_PSEAB ;  Q9I387, GLSA_PSEAE ;  Q1I8G2, GLSA_PSEE4 ;
DR   Q4KBW8, GLSA_PSEF5 ;  C3JXF9, GLSA_PSEFS ;  Q3IHY7, GLSA_PSEHT ;
DR   A4XNJ7, GLSA_PSEMY ;  A5W5B3, GLSA_PSEP1 ;  Q3KAU3, GLSA_PSEPF ;
DR   Q882Y4, GLSA_PSESM ;  Q4ZU37, GLSA_PSEU2 ;  A4VFZ6, GLSA_PSEU5 ;
DR   Q1QB42, GLSA_PSYCK ;  Q8XQS6, GLSA_RALSO ;  B3PPT2, GLSA_RHIE6 ;
DR   O87405, GLSA_RHIEC ;  Q1MG12, GLSA_RHIL3 ;  Q98NB7, GLSA_RHILO ;
DR   B5ZRF0, GLSA_RHILW ;  Q92PH0, GLSA_RHIME ;  C3MD81, GLSA_RHISN ;
DR   Q2J097, GLSA_RHOP2 ;  Q6N239, GLSA_RHOPA ;  Q218T3, GLSA_RHOPB ;
DR   Q13BB8, GLSA_RHOPS ;  B3QKT6, GLSA_RHOPT ;  Q21GQ5, GLSA_SACD2 ;
DR   A4FAB4, GLSA_SACEN ;  B5F610, GLSA_SALA4 ;  A9MRQ5, GLSA_SALAR ;
DR   Q57PB3, GLSA_SALCH ;  B5FHM8, GLSA_SALDC ;  B5QTS1, GLSA_SALEP ;
DR   B5RAE1, GLSA_SALG2 ;  B4THV9, GLSA_SALHS ;  B4T5R8, GLSA_SALNS ;
DR   Q5PN90, GLSA_SALPA ;  A9MYZ4, GLSA_SALPB ;  B4TVJ5, GLSA_SALSV ;
DR   Q8ZPI2, GLSA_SALTY ;  A8GJ45, GLSA_SERP5 ;  A1S8I4, GLSA_SHEAM ;
DR   B8E920, GLSA_SHEB2 ;  A3D705, GLSA_SHEB5 ;  A6WQU2, GLSA_SHEB8 ;
DR   A9KXQ3, GLSA_SHEB9 ;  A3QBZ9, GLSA_SHELP ;  Q8EBY0, GLSA_SHEON ;
DR   A4Y8Y3, GLSA_SHEPC ;  A0KUF0, GLSA_SHESA ;  Q0HL04, GLSA_SHESM ;
DR   Q0HXA2, GLSA_SHESR ;  A1RHL2, GLSA_SHESW ;  Q325B0, GLSA_SHIBS ;
DR   Q32G00, GLSA_SHIDS ;  A5VA34, GLSA_SPHWW ;  Q82NI9, GLSA_STRAW ;
DR   P57755, GLSA_STRCO ;  P73903, GLSA_SYNY3 ;  A5F9H5, GLSA_VIBC3 ;
DR   Q9KUR1, GLSA_VIBCH ;  Q5E7S8, GLSA_VIBF1 ;  B5F9R6, GLSA_VIBFM ;
DR   A7MTN6, GLSA_VIBHB ;  Q87LI9, GLSA_VIBPA ;  B7VKR3, GLSA_VIBSL ;
DR   Q8DCC2, GLSA_VIBVU ;  Q7MHI7, GLSA_VIBVY ;  Q1CEV6, GLSA_YERPN ;
DR   O94925, GLSK_HUMAN ;  P13264, GLSK_RAT   ;  Q9UI32, GLSL_HUMAN ;
DR   Q571F8, GLSL_MOUSE ;  P28492, GLSL_RAT   ;
//
ID   3.5.1.3
DE   Omega-amidase.
CA   A monoamide of a dicarboxylic acid + H(2)O = a dicarboxylate + NH(3).
CC   -!- Acts on glutaramate, succinamate and their 2-oxo derivatives.
DR   Q6IR61, NIT2A_XENLA;  Q6INI7, NIT2B_XENLA;  Q2T9R6, NIT2_BOVIN ;
DR   Q4VBV9, NIT2_DANRE ;  Q9NQR4, NIT2_HUMAN ;  Q9JHW2, NIT2_MOUSE ;
DR   Q5R4L6, NIT2_PONAB ;  Q497B0, NIT2_RAT   ;  Q28IE5, NIT2_XENTR ;
//
ID   3.5.1.4
DE   Amidase.
AN   Acylamidase.
AN   Acylase.
CA   A monocarboxylic acid amide + H(2)O = a monocarboxylate + NH(3).
PR   PROSITE; PDOC00494;
PR   PROSITE; PDOC50263;
DR   Q12559, AMDS_ASPOR ;  P08158, AMDS_EMENI ;  P22580, AMDY_YEAST ;
DR   P63495, AMI3_MYCBO ;  O33040, AMI3_MYCLE ;  P63494, AMI3_MYCTU ;
DR   P63497, AMI4_MYCBO ;  P63496, AMI4_MYCTU ;  P63491, AMIA2_MYCBO;
DR   P63490, AMIA2_MYCTU;  P63493, AMIB2_MYCBO;  P63492, AMIB2_MYCTU;
DR   P27765, AMID_PSECL ;  O69768, AMID_PSEPU ;  P22984, AMID_RHOER ;
DR   P84650, AMID_RHORH ;  P95896, AMID_SULSO ;  Q55424, AMID_SYNY3 ;
DR   Q0VN20, AMIE_ALCBS ;  Q9L543, AMIE_BACSP ;  Q89VS2, AMIE_BRAJA ;
DR   A5EDA7, AMIE_BRASB ;  A4Z057, AMIE_BRASO ;  Q1BP24, AMIE_BURCA ;
DR   B1K2X7, AMIE_BURCC ;  A0B137, AMIE_BURCH ;  A9C011, AMIE_DELAS ;
DR   Q9RQ17, AMIE_GEOSE ;  Q17YA2, AMIE_HELAH ;  B6JKM3, AMIE_HELP2 ;
DR   B5ZA60, AMIE_HELPG ;  Q1CUK9, AMIE_HELPH ;  Q9ZME1, AMIE_HELPJ ;
DR   B2USC5, AMIE_HELPS ;  O25067, AMIE_HELPY ;  A1U7G1, AMIE_MARAV ;
DR   Q5Z1U0, AMIE_NOCFA ;  A6V262, AMIE_PSEA7 ;  B7V2X1, AMIE_PSEA8 ;
DR   Q02QK0, AMIE_PSEAB ;  P11436, AMIE_PSEAE ;  C3K9E6, AMIE_PSEFS ;
DR   A5W2C0, AMIE_PSEP1 ;  C0ZNE8, AMIE_RHOE4 ;  Q01360, AMIE_RHOER ;
DR   B8GQ39, AMIE_THISH ;  C5CWZ4, AMIE_VARPS ;  O28325, Y1954_ARCFU;
DR   Q9URY4, YI01_SCHPO ;  O59805, YJV7_SCHPO ;  Q8TFF9, YP23_SCHPO ;
//
ID   3.5.1.5
DE   Urease.
CA   Urea + H(2)O = CO(2) + 2 NH(3).
CF   Nickel.
PR   PROSITE; PDOC00133;
DR   Q2YPD5, URE11_BRUA2;  Q93T81, URE11_BRUAB;  Q8YF72, URE11_BRUME;
DR   Q8G2P8, URE11_BRUSU;  Q4ZUD2, URE11_PSEU2;  Q1QCE0, URE11_PSYCK;
DR   Q82JN9, URE11_STRAW;  Q9FCD3, URE11_STRCO;  Q2YQD8, URE12_BRUA2;
DR   Q57CE8, URE12_BRUAB;  Q8YHZ8, URE12_BRUME;  Q8FZW2, URE12_BRUSU;
DR   Q4ZN06, URE12_PSEU2;  Q1QC36, URE12_PSYCK;  Q826R9, URE12_STRAW;
DR   O86508, URE12_STRCO;  A1TSZ6, URE1_ACIAC ;  Q6FD83, URE1_ACIAD ;
DR   A3N2R4, URE1_ACTP2 ;  B3H2L3, URE1_ACTP7 ;  B0BRU2, URE1_ACTPJ ;
DR   O54420, URE1_ACTPL ;  B9J8M3, URE1_AGRRK ;  Q8UCT2, URE1_AGRT5 ;
DR   B9JR81, URE1_AGRVS ;  Q0VKY1, URE1_ALCBS ;  B4RSX9, URE1_ALTMD ;
DR   A7HHN1, URE1_ANADF ;  B4UFU2, URE1_ANASK ;  Q3M712, URE1_ANAVT ;
DR   A8ESZ8, URE1_ARCB4 ;  A1R1C5, URE1_ARTAT ;  B8HA07, URE1_ARTCA ;
DR   A0JRH4, URE1_ARTS2 ;  B6YQL8, URE1_AZOPC ;  A1KBB4, URE1_AZOSB ;
DR   A7Z9N4, URE1_BACA2 ;  Q733J6, URE1_BACC1 ;  Q9KG59, URE1_BACHD ;
DR   P41020, URE1_BACPA ;  Q07397, URE1_BACSB ;  P77837, URE1_BACSU ;
DR   B2IIJ1, URE1_BEII9 ;  Q7VRS6, URE1_BLOFL ;  Q492E9, URE1_BLOPB ;
DR   O08400, URE1_BORBR ;  Q7W417, URE1_BORPA ;  Q7VUD3, URE1_BORPE ;
DR   Q89UG0, URE1_BRAJA ;  B1YUF9, URE1_BURA4 ;  Q1BYH2, URE1_BURCA ;
DR   B1JX29, URE1_BURCC ;  A0K576, URE1_BURCH ;  B4ECC7, URE1_BURCJ ;
DR   Q0BHN5, URE1_BURCM ;  A9AF72, URE1_BURM1 ;  A3MMV2, URE1_BURM7 ;
DR   A2S996, URE1_BURM9 ;  Q62HS0, URE1_BURMA ;  A1V1G6, URE1_BURMS ;
DR   A3NYC9, URE1_BURP0 ;  Q3JPJ6, URE1_BURP1 ;  A3NCL7, URE1_BURP6 ;
DR   Q63RL3, URE1_BURPS ;  Q39IW3, URE1_BURS3 ;  Q2SYF7, URE1_BURTA ;
DR   A4JC42, URE1_BURVG ;  A4XMA9, URE1_CALS8 ;  Q5FB23, URE1_CAMLA ;
DR   A8APV0, URE1_CITK8 ;  P94669, URE1_CLOPE ;  A9KJR9, URE1_CLOPH ;
DR   A3DGF8, URE1_CLOTH ;  Q8FQX2, URE1_COREF ;  Q79VJ3, URE1_CORGL ;
DR   B1VHT2, URE1_CORU7 ;  Q0KCP6, URE1_CUPNH ;  Q473Q9, URE1_CUPPJ ;
DR   B8HW50, URE1_CYAP4 ;  B7K912, URE1_CYAP7 ;  Q11VN3, URE1_CYTH3 ;
DR   Q47G55, URE1_DECAR ;  Q9RYJ4, URE1_DEIRA ;  A9BUC4, URE1_DELAS ;
DR   A8LRS0, URE1_DINSH ;  Q8XAG0, URE1_ECO57 ;  B5YUX3, URE1_ECO5E ;
DR   Q03284, URE1_ECOLX ;  C5BBR6, URE1_EDWI9 ;  A4WEJ5, URE1_ENT38 ;
DR   P18314, URE1_ENTAE ;  A5FAD1, URE1_FLAJ1 ;  Q0RQS0, URE1_FRAAA ;
DR   Q2JES6, URE1_FRASC ;  A8L7B0, URE1_FRASN ;  Q5KYM1, URE1_GEOKA ;
DR   Q4QN09, URE1_HAEI8 ;  A5U9V6, URE1_HAEIE ;  A5UH45, URE1_HAEIG ;
DR   P44391, URE1_HAEIN ;  Q2SDQ1, URE1_HAHCH ;  Q75ZQ5, URE1_HALMA ;
DR   Q18EB9, URE1_HALWD ;  Q08716, URE1_HELFC ;  P42823, URE1_HELHE ;
DR   Q93PJ4, URE1_HELHP ;  P50045, URE1_HELMU ;  B6JPH5, URE1_HELP2 ;
DR   B5Z674, URE1_HELPG ;  Q1CV82, URE1_HELPH ;  P69997, URE1_HELPJ ;
DR   B2UW70, URE1_HELPS ;  P69996, URE1_HELPY ;  A9AZE6, URE1_HERA2 ;
DR   A6SZ07, URE1_JANMA ;  Q28RJ3, URE1_JANSC ;  B5XU27, URE1_KLEP3 ;
DR   A6TE42, URE1_KLEP7 ;  B2GI06, URE1_KOCRD ;  P26929, URE1_LACFE ;
DR   C1D5Z8, URE1_LARHH ;  B1Y3V1, URE1_LEPCP ;  P50046, URE1_LISDA ;
DR   A0L6F2, URE1_MAGSM ;  A1U4Z8, URE1_MARAV ;  A6VTV8, URE1_MARMS ;
DR   Q11EW4, URE1_MESSB ;  Q1H0F2, URE1_METFK ;  A2SDJ0, URE1_METPP ;
DR   B8EPU9, URE1_METSB ;  B0JKA1, URE1_MICAN ;  C5C8U3, URE1_MICLC ;
DR   P17337, URE1_MORMO ;  B1MB85, URE1_MYCA9 ;  P0A661, URE1_MYCBO ;
DR   A1KJR2, URE1_MYCBP ;  C1APC7, URE1_MYCBT ;  B2HSZ2, URE1_MYCMM ;
DR   A0QYE0, URE1_MYCS2 ;  A3Q0D5, URE1_MYCSJ ;  A1UGT5, URE1_MYCSK ;
DR   Q1B872, URE1_MYCSS ;  A5U3L7, URE1_MYCTA ;  P0A660, URE1_MYCTU ;
DR   A0PSG2, URE1_MYCUA ;  A1T9N4, URE1_MYCVP ;  Q3IRZ5, URE1_NATPD ;
DR   Q2Y9M7, URE1_NITMU ;  Q3J770, URE1_NITOC ;  Q5YWR8, URE1_NOCFA ;
DR   B2IT66, URE1_NOSP7 ;  Q8YQZ0, URE1_NOSS1 ;  B1ZP06, URE1_OPITP ;
DR   A1B1B9, URE1_PARDP ;  Q7N4Y7, URE1_PHOLL ;  A1VKW3, URE1_POLNA ;
DR   Q12DU3, URE1_POLSJ ;  A4SY44, URE1_POLSQ ;  P16122, URE1_PROHU ;
DR   A3PCP1, URE1_PROM0 ;  A2C4S2, URE1_PROM1 ;  A8G4K9, URE1_PROM2 ;
DR   A2CE01, URE1_PROM3 ;  Q31B49, URE1_PROM9 ;  P17086, URE1_PROMH ;
DR   Q7V3V2, URE1_PROMM ;  Q7V1B6, URE1_PROMP ;  A2BQW8, URE1_PROMS ;
DR   Q46IY3, URE1_PROMT ;  Q9L644, URE1_PROS9 ;  Q48DE6, URE1_PSE14 ;
DR   Q9HUU5, URE1_PSEAE ;  Q1IBP0, URE1_PSEE4 ;  Q4KJ10, URE1_PSEF5 ;
DR   Q3IH68, URE1_PSEHT ;  A5W4B6, URE1_PSEP1 ;  Q3KIT2, URE1_PSEPF ;
DR   B0KUZ7, URE1_PSEPG ;  Q88J04, URE1_PSEPK ;  B1J815, URE1_PSEPW ;
DR   Q87VP0, URE1_PSESM ;  A1SYY1, URE1_PSYIN ;  Q8XXT1, URE1_RALSO ;
DR   B3PXB3, URE1_RHIE6 ;  Q2K517, URE1_RHIEC ;  Q1MCV9, URE1_RHIL3 ;
DR   Q98CY9, URE1_RHILO ;  B5ZMP0, URE1_RHILW ;  P42885, URE1_RHIME ;
DR   C3MGI5, URE1_RHISN ;  Q21SZ2, URE1_RHOFD ;  C1AXZ2, URE1_RHOOB ;
DR   Q2IZ49, URE1_RHOP2 ;  Q07K73, URE1_RHOP5 ;  Q6N3N3, URE1_RHOPA ;
DR   Q210F9, URE1_RHOPB ;  Q133L6, URE1_RHOPS ;  B3QGK1, URE1_RHOPT ;
DR   A3PL38, URE1_RHOS1 ;  Q3J154, URE1_RHOS4 ;  A4WR75, URE1_RHOS5 ;
DR   B9KK46, URE1_RHOSK ;  Q0S4S7, URE1_RHOSR ;  Q161S8, URE1_ROSDO ;
DR   Q21P94, URE1_SACD2 ;  B0TT71, URE1_SHEHH ;  Q5LSQ2, URE1_SILPO ;
DR   Q1GJP8, URE1_SILST ;  A6UC35, URE1_SINMW ;  A9GP84, URE1_SORC5 ;
DR   A7X5M3, URE1_STAA1 ;  A6U414, URE1_STAA2 ;  Q2FEK3, URE1_STAA3 ;
DR   Q2G2K5, URE1_STAA8 ;  A5IV71, URE1_STAA9 ;  Q2YYQ6, URE1_STAAB ;
DR   Q5HDR8, URE1_STAAC ;  A6QJD0, URE1_STAAE ;  P67403, URE1_STAAM ;
DR   P67404, URE1_STAAN ;  Q6GEE4, URE1_STAAR ;  Q6G732, URE1_STAAS ;
DR   A8Z387, URE1_STAAT ;  P67405, URE1_STAAW ;  B9DLY0, URE1_STACT ;
DR   Q5HLW1, URE1_STAEQ ;  Q8CNC9, URE1_STAES ;  Q4A0J5, URE1_STAS1 ;
DR   P42873, URE1_STAXY ;  P50047, URE1_STRSL ;  Q5M1G6, URE1_STRT1 ;
DR   Q5M607, URE1_STRT2 ;  Q03ME3, URE1_STRTD ;  Q972W0, URE1_SULTO ;
DR   Q2JWP0, URE1_SYNJA ;  Q2JQ88, URE1_SYNJB ;  O87402, URE1_SYNPV ;
DR   Q7U3I3, URE1_SYNPX ;  A5GWV7, URE1_SYNR3 ;  Q0I656, URE1_SYNS3 ;
DR   Q3AVR1, URE1_SYNS9 ;  Q3AGD0, URE1_SYNSC ;  P73061, URE1_SYNY3 ;
DR   C5BUN9, URE1_TERTT ;  Q8DMV6, URE1_THEEB ;  C4LF63, URE1_TOLAT ;
DR   Q117Z3, URE1_TRIEI ;  B1AJ73, URE1_UREP2 ;  P0C7K7, URE1_UREPA ;
DR   B5ZBS9, URE1_UREU1 ;  P0CB00, URE1_UREUR ;  C5CY00, URE1_VARPS ;
DR   A1WIM3, URE1_VEREI ;  Q5E728, URE1_VIBF1 ;  B5FBC6, URE1_VIBFM ;
DR   A1JKD9, URE1_YERE8 ;  P31494, URE1_YEREN ;  A7FFN2, URE1_YERP3 ;
DR   Q1C5B3, URE1_YERPA ;  B2KAA4, URE1_YERPB ;  Q9ZFR9, URE1_YERPE ;
DR   A9R3V0, URE1_YERPG ;  Q1CKJ9, URE1_YERPN ;  A4TL32, URE1_YERPP ;
DR   P52313, URE1_YERPS ;  B1JR71, URE1_YERPY ;  Q2YPD6, URE21_BRUA2;
DR   P0C1D5, URE21_BRUAB;  Q7CNT2, URE21_BRUME;  Q8G2P9, URE21_BRUSU;
DR   Q2YQD9, URE22_BRUA2;  Q57CE9, URE22_BRUAB;  Q8YHZ7, URE22_BRUME;
DR   Q8FZW3, URE22_BRUSU;  Q5FB24, URE23_CAMLA;  Q9RYJ3, URE23_DEIRA;
DR   Q17VS7, URE23_HELAH;  Q8GH98, URE23_HELBI;  Q08715, URE23_HELFE;
DR   P42822, URE23_HELHE;  Q93PJ5, URE23_HELHP;  P50044, URE23_HELMU;
DR   B6JPH6, URE23_HELP2;  Q1CV81, URE23_HELPH;  Q9ZMZ4, URE23_HELPJ;
DR   B2UW71, URE23_HELPS;  P14916, URE23_HELPY;  Q883F3, URE23_PSESM;
DR   Q4ZUD1, URE23_PSEU2;  Q82JN8, URE23_STRAW;  O86507, URE23_STRCO;
DR   Q972V9, URE23_SULTO;  B0C793, URE2_ACAM1 ;  A1TSZ5, URE2_ACIAC ;
DR   Q6FD84, URE2_ACIAD ;  B7GXU4, URE2_ACIB3 ;  B7I8T4, URE2_ACIB5 ;
DR   B2HVR9, URE2_ACIBC ;  B0VSC1, URE2_ACIBS ;  A3M3F1, URE2_ACIBT ;
DR   B0V9P6, URE2_ACIBY ;  A3N2R5, URE2_ACTP2 ;  B3H2L4, URE2_ACTP7 ;
DR   B0BRU3, URE2_ACTPJ ;  O54419, URE2_ACTPL ;  B9J8M5, URE2_AGRRK ;
DR   Q8UCS8, URE2_AGRT5 ;  B9JR84, URE2_AGRVS ;  Q0VKY0, URE2_ALCBS ;
DR   Q0AC99, URE2_ALHEH ;  B4RSX8, URE2_ALTMD ;  Q3M710, URE2_ANAVT ;
DR   A1R1C4, URE2_ARTAT ;  B8HA06, URE2_ARTCA ;  A0JRH3, URE2_ARTS2 ;
DR   A1KBB5, URE2_AZOSB ;  C1DNK5, URE2_AZOVD ;  A7Z9N5, URE2_BACA2 ;
DR   Q733J5, URE2_BACC1 ;  Q9KG60, URE2_BACHD ;  P41021, URE2_BACPA ;
DR   Q07398, URE2_BACSB ;  P71035, URE2_BACSU ;  Q7VRS5, URE2_BLOFL ;
DR   Q492E8, URE2_BLOPB ;  P0A4R2, URE2_BORBR ;  P0A4R3, URE2_BORPA ;
DR   Q7VUD2, URE2_BORPE ;  Q89UG2, URE2_BRAJA ;  A5ERV2, URE2_BRASB ;
DR   A4YM26, URE2_BRASO ;  B1YUG0, URE2_BURA4 ;  Q1BYH1, URE2_BURCA ;
DR   B1JX30, URE2_BURCC ;  A0K577, URE2_BURCH ;  B4ECC6, URE2_BURCJ ;
DR   Q0BHN4, URE2_BURCM ;  A9AF71, URE2_BURM1 ;  A3MMV1, URE2_BURM7 ;
DR   A2S997, URE2_BURM9 ;  Q62HS1, URE2_BURMA ;  A1V1G7, URE2_BURMS ;
DR   A3NYC8, URE2_BURP0 ;  Q3JPJ7, URE2_BURP1 ;  A3NCL6, URE2_BURP6 ;
DR   B2JF66, URE2_BURP8 ;  B2T0P6, URE2_BURPP ;  Q63RL4, URE2_BURPS ;
DR   Q39IW2, URE2_BURS3 ;  Q2SYF6, URE2_BURTA ;  A4JC43, URE2_BURVG ;
DR   Q144E3, URE2_BURXL ;  Q1QV52, URE2_CHRSD ;  A8APU9, URE2_CITK8 ;
DR   P94668, URE2_CLOPE ;  A9KJS0, URE2_CLOPH ;  A3DGF9, URE2_CLOTH ;
DR   Q8FQX3, URE2_COREF ;  A4QA22, URE2_CORGB ;  Q79VJ4, URE2_CORGL ;
DR   Q0KCP7, URE2_CUPNH ;  Q473R0, URE2_CUPPJ ;  B3R401, URE2_CUPTR ;
DR   B8HW51, URE2_CYAP4 ;  B7K907, URE2_CYAP7 ;  Q47G54, URE2_DECAR ;
DR   A8LRS3, URE2_DINSH ;  Q8XAG1, URE2_ECO57 ;  B5YUX2, URE2_ECO5E ;
DR   Q03283, URE2_ECOLX ;  A4WEJ4, URE2_ENT38 ;  P18315, URE2_ENTAE ;
DR   A5FAD2, URE2_FLAJ1 ;  Q0RQR9, URE2_FRAAA ;  Q2JES5, URE2_FRASC ;
DR   Q5KYM0, URE2_GEOKA ;  Q0BQ41, URE2_GRABC ;  Q4QN08, URE2_HAEI8 ;
DR   A5U9V5, URE2_HAEIE ;  P44392, URE2_HAEIN ;  Q2SDQ2, URE2_HAHCH ;
DR   Q75ZQ6, URE2_HALMA ;  Q18EC0, URE2_HALWD ;  A9AZE7, URE2_HERA2 ;
DR   A6SZ06, URE2_JANMA ;  Q28RJ8, URE2_JANSC ;  B5XU28, URE2_KLEP3 ;
DR   A6TE41, URE2_KLEP7 ;  B2GI07, URE2_KOCRD ;  P26930, URE2_LACFE ;
DR   B1Y3V2, URE2_LEPCP ;  B1HZE3, URE2_LYSSC ;  A0L6F1, URE2_MAGSM ;
DR   A1U4Z9, URE2_MARAV ;  A6VTV7, URE2_MARMS ;  Q11EW5, URE2_MESSB ;
DR   Q1H0F1, URE2_METFK ;  A2SDJ1, URE2_METPP ;  B8EPV0, URE2_METSB ;
DR   B0JTP2, URE2_MICAN ;  C5C8U2, URE2_MICLC ;  P17338, URE2_MORMO ;
DR   P0A663, URE2_MYCBO ;  A1KJR1, URE2_MYCBP ;  C1APC6, URE2_MYCBT ;
DR   B2HSZ1, URE2_MYCMM ;  A3Q0D6, URE2_MYCSJ ;  A1UGT6, URE2_MYCSK ;
DR   Q1B871, URE2_MYCSS ;  A5U3L6, URE2_MYCTA ;  P0A662, URE2_MYCTU ;
DR   A0PSG3, URE2_MYCUA ;  A1T9N5, URE2_MYCVP ;  Q3IRZ6, URE2_NATPD ;
DR   Q2Y9M8, URE2_NITMU ;  Q3J769, URE2_NITOC ;  Q5YWR9, URE2_NOCFA ;
DR   B2IT65, URE2_NOSP7 ;  Q8YQZ2, URE2_NOSS1 ;  B1ZP07, URE2_OPITP ;
DR   Q7N4Y8, URE2_PHOLL ;  A1VKW4, URE2_POLNA ;  Q12DU2, URE2_POLSJ ;
DR   P16123, URE2_PROHU ;  A3PCP0, URE2_PROM0 ;  A2C4S1, URE2_PROM1 ;
DR   A8G4K8, URE2_PROM2 ;  A2CE00, URE2_PROM3 ;  Q31B50, URE2_PROM9 ;
DR   P17087, URE2_PROMH ;  Q7V3V3, URE2_PROMM ;  Q7V1B5, URE2_PROMP ;
DR   A2BQW7, URE2_PROMS ;  Q46IY4, URE2_PROMT ;  Q48DE7, URE2_PSE14 ;
DR   A6VCX4, URE2_PSEA7 ;  B7V1T0, URE2_PSEA8 ;  Q02FF2, URE2_PSEAB ;
DR   Q9HUU6, URE2_PSEAE ;  Q1IBP1, URE2_PSEE4 ;  Q4KJ09, URE2_PSEF5 ;
DR   C3K5A2, URE2_PSEFS ;  Q3IH69, URE2_PSEHT ;  A4XQ45, URE2_PSEMY ;
DR   Q3KIT1, URE2_PSEPF ;  B0KUZ8, URE2_PSEPG ;  Q88J05, URE2_PSEPK ;
DR   B1J814, URE2_PSEPW ;  Q87VP1, URE2_PSESM ;  Q4ZN07, URE2_PSEU2 ;
DR   A4VQV0, URE2_PSEU5 ;  Q1QCE1, URE2_PSYCK ;  A1SYY0, URE2_PSYIN ;
DR   Q1LPT0, URE2_RALME ;  B2U7N2, URE2_RALPJ ;  Q8XXT0, URE2_RALSO ;
DR   B3PXB6, URE2_RHIE6 ;  Q2K514, URE2_RHIEC ;  Q1MCV6, URE2_RHIL3 ;
DR   Q98CY6, URE2_RHILO ;  B5ZMP3, URE2_RHILW ;  P42886, URE2_RHIME ;
DR   C3MGX4, URE2_RHISN ;  Q21SZ4, URE2_RHOFD ;  C1AXZ1, URE2_RHOOB ;
DR   Q2IZ51, URE2_RHOP2 ;  Q07K71, URE2_RHOP5 ;  Q6N3N1, URE2_RHOPA ;
DR   Q210F6, URE2_RHOPB ;  Q133L3, URE2_RHOPS ;  B3QGK3, URE2_RHOPT ;
DR   A3PL41, URE2_RHOS1 ;  Q3J151, URE2_RHOS4 ;  A4WR73, URE2_RHOS5 ;
DR   B9KK50, URE2_RHOSK ;  Q0S4S8, URE2_RHOSR ;  Q161T1, URE2_ROSDO ;
DR   Q21P95, URE2_SACD2 ;  A4F7F6, URE2_SACEN ;  B0TT70, URE2_SHEHH ;
DR   Q5LSQ3, URE2_SILPO ;  Q1GJP7, URE2_SILST ;  A6UC38, URE2_SINMW ;
DR   A7X5M0, URE2_STAA1 ;  A6U413, URE2_STAA2 ;  Q2FEK4, URE2_STAA3 ;
DR   Q2G2K6, URE2_STAA8 ;  A5IV70, URE2_STAA9 ;  Q2YYQ7, URE2_STAAB ;
DR   Q5HDR9, URE2_STAAC ;  A6QJC9, URE2_STAAE ;  P67406, URE2_STAAM ;
DR   P67407, URE2_STAAN ;  Q6GEE5, URE2_STAAR ;  Q6G733, URE2_STAAS ;
DR   A8Z386, URE2_STAAT ;  Q8NV90, URE2_STAAW ;  B9DLX9, URE2_STACT ;
DR   Q5HLW2, URE2_STAEQ ;  Q8CND0, URE2_STAES ;  Q4A0J4, URE2_STAS1 ;
DR   P42874, URE2_STAXY ;  Q826S0, URE2_STRAW ;  Q9FCD2, URE2_STRCO ;
DR   B1W5G8, URE2_STRGG ;  Q55054, URE2_STRSL ;  Q5M1G7, URE2_STRT1 ;
DR   Q5M608, URE2_STRT2 ;  Q03ME4, URE2_STRTD ;  O87401, URE2_SYNPV ;
DR   Q7U3I4, URE2_SYNPX ;  A5GWV6, URE2_SYNR3 ;  Q0I657, URE2_SYNS3 ;
DR   Q3AVR2, URE2_SYNS9 ;  Q3AGD1, URE2_SYNSC ;  P74386, URE2_SYNY3 ;
DR   C5BUP0, URE2_TERTT ;  Q8DLZ6, URE2_THEEB ;  B8GQ25, URE2_THISH ;
DR   C4LF64, URE2_TOLAT ;  Q117Z8, URE2_TRIEI ;  B1AJ74, URE2_UREP2 ;
DR   P0C7K8, URE2_UREPA ;  B5ZBT0, URE2_UREU1 ;  P0CB01, URE2_UREUR ;
DR   C5CXZ9, URE2_VARPS ;  A1WIM4, URE2_VEREI ;  Q5E727, URE2_VIBF1 ;
DR   B5FBC7, URE2_VIBFM ;  A1JKD8, URE2_YERE8 ;  P31495, URE2_YEREN ;
DR   A7FFN1, URE2_YERP3 ;  P69990, URE2_YERPE ;  P69991, URE2_YERPS ;
DR   Q2YPD7, URE31_BRUA2;  P0C121, URE31_BRUAB;  Q8YF71, URE31_BRUME;
DR   Q8G2Q0, URE31_BRUSU;  Q1QCE2, URE31_PSYCK;  Q2YQE0, URE32_BRUA2;
DR   Q57CF0, URE32_BRUAB;  Q8YHZ6, URE32_BRUME;  Q8FZW4, URE32_BRUSU;
DR   Q1QC34, URE32_PSYCK;  B0C791, URE3_ACAM1 ;  A1TSZ3, URE3_ACIAC ;
DR   Q6FD85, URE3_ACIAD ;  B7GXU5, URE3_ACIB3 ;  B7I8T3, URE3_ACIB5 ;
DR   B2HVR8, URE3_ACIBC ;  B0VSC2, URE3_ACIBS ;  A3M3F0, URE3_ACIBT ;
DR   B0V9P7, URE3_ACIBY ;  Q9Z395, URE3_ACTNA ;  A3N2R6, URE3_ACTP2 ;
DR   B3H2L5, URE3_ACTP7 ;  B0BRU4, URE3_ACTPJ ;  O54418, URE3_ACTPL ;
DR   B9J8M6, URE3_AGRRK ;  Q8UCS6, URE3_AGRT5 ;  B9JR86, URE3_AGRVS ;
DR   Q0VKX9, URE3_ALCBS ;  Q0ACA0, URE3_ALHEH ;  B4RSX7, URE3_ALTMD ;
DR   Q3M709, URE3_ANAVT ;  A1R1C3, URE3_ARTAT ;  B8HA05, URE3_ARTCA ;
DR   A0JRH2, URE3_ARTS2 ;  A1KBB7, URE3_AZOSB ;  C1DNK6, URE3_AZOVD ;
DR   Q733J4, URE3_BACC1 ;  Q9KG61, URE3_BACHD ;  P41022, URE3_BACPA ;
DR   Q07399, URE3_BACSB ;  P75030, URE3_BACSU ;  Q7VRS4, URE3_BLOFL ;
DR   Q492E7, URE3_BLOPB ;  P0A4U0, URE3_BORBR ;  P0A4U1, URE3_BORPA ;
DR   Q7VUD0, URE3_BORPE ;  Q89UG3, URE3_BRAJA ;  B1YUG1, URE3_BURA4 ;
DR   Q1BYH0, URE3_BURCA ;  B1JX31, URE3_BURCC ;  A0K578, URE3_BURCH ;
DR   B4ECC5, URE3_BURCJ ;  Q0BHN3, URE3_BURCM ;  A9AF70, URE3_BURM1 ;
DR   A3MMV0, URE3_BURM7 ;  A2S998, URE3_BURM9 ;  Q62HS2, URE3_BURMA ;
DR   A1V1G8, URE3_BURMS ;  A3NYC7, URE3_BURP0 ;  Q3JPJ8, URE3_BURP1 ;
DR   A3NCL5, URE3_BURP6 ;  B2JF65, URE3_BURP8 ;  B2T0P7, URE3_BURPP ;
DR   Q63RL5, URE3_BURPS ;  Q39IW1, URE3_BURS3 ;  Q2SYF5, URE3_BURTA ;
DR   A4JC44, URE3_BURVG ;  Q144E2, URE3_BURXL ;  Q1QV51, URE3_CHRSD ;
DR   A8APU8, URE3_CITK8 ;  P94667, URE3_CLOPE ;  A9KJS1, URE3_CLOPH ;
DR   A3DGG0, URE3_CLOTH ;  Q8FQX4, URE3_COREF ;  A4QA21, URE3_CORGB ;
DR   Q9RHM6, URE3_CORGL ;  C4LIA9, URE3_CORK4 ;  B1VHT0, URE3_CORU7 ;
DR   O30334, URE3_CUPNH ;  Q473R2, URE3_CUPPJ ;  B3R3Z9, URE3_CUPTR ;
DR   B8HW52, URE3_CYAP4 ;  B7K906, URE3_CYAP7 ;  Q47G53, URE3_DECAR ;
DR   A9BUC7, URE3_DELAS ;  A8LRS4, URE3_DINSH ;  Q8XAG2, URE3_ECO57 ;
DR   B5YUX1, URE3_ECO5E ;  Q03282, URE3_ECOLX ;  C5BDC2, URE3_EDWI9 ;
DR   A4WEJ3, URE3_ENT38 ;  P18316, URE3_ENTAE ;  A5FAD3, URE3_FLAJ1 ;
DR   Q0RQR8, URE3_FRAAA ;  Q2JES4, URE3_FRASC ;  Q5KYL9, URE3_GEOKA ;
DR   Q0BQ42, URE3_GRABC ;  Q4QN07, URE3_HAEI8 ;  A5U9V4, URE3_HAEIE ;
DR   A5UH46, URE3_HAEIG ;  P44393, URE3_HAEIN ;  Q2SDQ3, URE3_HAHCH ;
DR   Q75ZQ4, URE3_HALMA ;  Q18EB8, URE3_HALWD ;  A9AZE8, URE3_HERA2 ;
DR   Q28RK0, URE3_JANSC ;  B5XU29, URE3_KLEP3 ;  A6TE40, URE3_KLEP7 ;
DR   Q02943, URE3_KLEPN ;  B2GI08, URE3_KOCRD ;  P26931, URE3_LACFE ;
DR   C1D5Z6, URE3_LARHH ;  B1Y3V4, URE3_LEPCP ;  B1HZE2, URE3_LYSSC ;
DR   A0L6F0, URE3_MAGSM ;  A1U500, URE3_MARAV ;  A6VTV6, URE3_MARMS ;
DR   Q11EW7, URE3_MESSB ;  Q1H0F0, URE3_METFK ;  A2SDJ2, URE3_METPP ;
DR   B8EPV1, URE3_METSB ;  B0JTP1, URE3_MICAN ;  C5C8U1, URE3_MICLC ;
DR   P17339, URE3_MORMO ;  B1MB83, URE3_MYCA9 ;  P0A677, URE3_MYCBO ;
DR   A1KJR0, URE3_MYCBP ;  C1APC5, URE3_MYCBT ;  A4TAD3, URE3_MYCGI ;
DR   A0QYE2, URE3_MYCS2 ;  A3Q0D7, URE3_MYCSJ ;  A1UGT7, URE3_MYCSK ;
DR   Q1B870, URE3_MYCSS ;  A5U3L5, URE3_MYCTA ;  P0A676, URE3_MYCTU ;
DR   A0PSG4, URE3_MYCUA ;  A1T9N6, URE3_MYCVP ;  Q3IRZ4, URE3_NATPD ;
DR   Q2Y9M9, URE3_NITMU ;  Q3J768, URE3_NITOC ;  Q5YWS0, URE3_NOCFA ;
DR   B2IT64, URE3_NOSP7 ;  Q8YQZ3, URE3_NOSS1 ;  B1ZP08, URE3_OPITP ;
DR   A1B1C2, URE3_PARDP ;  Q7N4Y9, URE3_PHOLL ;  A1VKW6, URE3_POLNA ;
DR   Q12DU1, URE3_POLSJ ;  A4SY47, URE3_POLSQ ;  P16124, URE3_PROHU ;
DR   A3PCN9, URE3_PROM0 ;  A2C4S0, URE3_PROM1 ;  A8G4K7, URE3_PROM2 ;
DR   A2CDZ9, URE3_PROM3 ;  Q31B51, URE3_PROM9 ;  P17088, URE3_PROMH ;
DR   Q7V3V4, URE3_PROMM ;  Q7V1B4, URE3_PROMP ;  A2BQW6, URE3_PROMS ;
DR   Q46IY5, URE3_PROMT ;  Q9L642, URE3_PROS9 ;  Q48DF0, URE3_PSE14 ;
DR   A6VCX2, URE3_PSEA7 ;  B7V1S8, URE3_PSEA8 ;  Q02FF4, URE3_PSEAB ;
DR   Q9HUU8, URE3_PSEAE ;  Q1IBP2, URE3_PSEE4 ;  Q4KJ06, URE3_PSEF5 ;
DR   C3K5A5, URE3_PSEFS ;  Q3IH70, URE3_PSEHT ;  A4XQ47, URE3_PSEMY ;
DR   A5W4B8, URE3_PSEP1 ;  Q3KIS8, URE3_PSEPF ;  B0KUZ9, URE3_PSEPG ;
DR   Q88J06, URE3_PSEPK ;  B1J813, URE3_PSEPW ;  Q87VP4, URE3_PSESM ;
DR   Q4ZN10, URE3_PSEU2 ;  A4VQU9, URE3_PSEU5 ;  A1SYX9, URE3_PSYIN ;
DR   Q1LPT2, URE3_RALME ;  B2U7N4, URE3_RALPJ ;  Q8XXS8, URE3_RALSO ;
DR   B3PXB8, URE3_RHIE6 ;  Q2K512, URE3_RHIEC ;  Q1MCV5, URE3_RHIL3 ;
DR   Q98CY3, URE3_RHILO ;  Q8RPY7, URE3_RHILV ;  B5ZMP5, URE3_RHILW ;
DR   P42887, URE3_RHIME ;  C3MGX6, URE3_RHISN ;  Q9AQT6, URE3_RHOCA ;
DR   Q21SZ5, URE3_RHOFD ;  C1AXZ0, URE3_RHOOB ;  Q2IZ52, URE3_RHOP2 ;
DR   Q07K70, URE3_RHOP5 ;  Q6N3N0, URE3_RHOPA ;  Q210F5, URE3_RHOPB ;
DR   Q133L2, URE3_RHOPS ;  B3QGK4, URE3_RHOPT ;  A3PL42, URE3_RHOS1 ;
DR   Q9RFF5, URE3_RHOS4 ;  A4WR72, URE3_RHOS5 ;  B9KK51, URE3_RHOSK ;
DR   Q0S4S9, URE3_RHOSR ;  Q161T2, URE3_ROSDO ;  Q21P96, URE3_SACD2 ;
DR   A4F7F5, URE3_SACEN ;  B0TT69, URE3_SHEHH ;  Q5LSQ4, URE3_SILPO ;
DR   Q1GJP6, URE3_SILST ;  A6UC40, URE3_SINMW ;  A7X5L9, URE3_STAA1 ;
DR   A6U412, URE3_STAA2 ;  Q2FEK5, URE3_STAA3 ;  Q2FVW5, URE3_STAA8 ;
DR   A5IV69, URE3_STAA9 ;  Q2YYQ8, URE3_STAAB ;  Q5HDS0, URE3_STAAC ;
DR   A6QJC8, URE3_STAAE ;  P67718, URE3_STAAM ;  P67719, URE3_STAAN ;
DR   Q6GEE6, URE3_STAAR ;  Q6G734, URE3_STAAS ;  A8Z385, URE3_STAAT ;
DR   P67720, URE3_STAAW ;  B9DLX8, URE3_STACT ;  Q5HLW3, URE3_STAEQ ;
DR   Q8CND1, URE3_STAES ;  Q4A0J3, URE3_STAS1 ;  P42875, URE3_STAXY ;
DR   Q826S1, URE3_STRAW ;  Q9FCD1, URE3_STRCO ;  B1W5G7, URE3_STRGG ;
DR   Q55053, URE3_STRSL ;  Q5M1G8, URE3_STRT1 ;  Q5M609, URE3_STRT2 ;
DR   Q03ME5, URE3_STRTD ;  Q83U21, URE3_STRTR ;  Q2JJ72, URE3_SYNJB ;
DR   B1XLM3, URE3_SYNP2 ;  O87400, URE3_SYNPV ;  Q7U3I5, URE3_SYNPX ;
DR   A5GWV5, URE3_SYNR3 ;  Q0I658, URE3_SYNS3 ;  Q3AVR3, URE3_SYNS9 ;
DR   Q3AGD2, URE3_SYNSC ;  P73796, URE3_SYNY3 ;  C6AR50, URE3_TERTT ;
DR   Q8DK85, URE3_THEEB ;  B8GQ24, URE3_THISH ;  C4LF65, URE3_TOLAT ;
DR   Q117Z9, URE3_TRIEI ;  B1AJ75, URE3_UREP2 ;  P0C7K9, URE3_UREPA ;
DR   B5ZBT1, URE3_UREU1 ;  P0CB02, URE3_UREUR ;  C5CXZ7, URE3_VARPS ;
DR   A1WIM6, URE3_VEREI ;  Q5E726, URE3_VIBF1 ;  B5FBC8, URE3_VIBFM ;
DR   Q9FAS7, URE3_VIBPA ;  Q6UR86, URE3_YERAL ;  Q6UR78, URE3_YERBE ;
DR   A1JKD7, URE3_YERE8 ;  P31496, URE3_YEREN ;  Q6UR70, URE3_YERFR ;
DR   Q6UR62, URE3_YERIN ;  Q6UR53, URE3_YERKR ;  Q6UR44, URE3_YERMO ;
DR   A7FFN0, URE3_YERP3 ;  Q1C5B5, URE3_YERPA ;  B2KAA6, URE3_YERPB ;
DR   P69994, URE3_YERPE ;  Q1CKK1, URE3_YERPN ;  A4TL34, URE3_YERPP ;
DR   P69995, URE3_YERPS ;  B1JR69, URE3_YERPY ;  Q6UR35, URE3_YERRO ;
DR   Q6A3P9, UREA_ASPFU ;  P07374, UREA_CANEN ;  P0CS23, UREA_CRYNB ;
DR   P0CS22, UREA_CRYNJ ;  O13465, UREA_CRYNV ;  O00084, UREA_SCHPO ;
DR   P08298, UREA_SOYBN ;
//
ID   3.5.1.6
DE   Beta-ureidopropionase.
CA   N-carbamoyl-beta-alanine + H(2)O = beta-alanine + CO(2) + NH(3).
CC   -!- The animal enzyme also acts on beta-ureidoisobutyrate.
PR   PROSITE; PDOC50263;
DR   Q964D8, BUP1_DICDI ;  Q9UBR1, BUP1_HUMAN ;  Q8VC97, BUP1_MOUSE ;
DR   Q5RBM6, BUP1_PONAB ;  Q03248, BUP1_RAT   ;
//
ID   3.5.1.7
DE   Ureidosuccinase.
CA   N-carbamoyl-L-aspartate + H(2)O = L-aspartate + CO(2) + NH(3).
//
ID   3.5.1.8
DE   Formylaspartate deformylase.
CA   N-formyl-L-aspartate + H(2)O = formate + L-aspartate.
//
ID   3.5.1.9
DE   Arylformamidase.
AN   Formylase.
AN   Formylkynureninase.
AN   Kynurenine formamidase.
CA   N-formyl-L-kynurenine + H(2)O = formate + L-kynurenine.
CC   -!- Also acts on other aromatic formylamines.
DR   Q566U4, AFMID_DANRE;  Q63HM1, AFMID_HUMAN;  Q8K4H1, AFMID_MOUSE;
DR   B5XB27, AFMID_SALSA;  Q759T3, BNA7_ASHGO ;  Q59ZV4, BNA7_CANAL ;
DR   Q6BT11, BNA7_DEBHA ;  A5DNX8, BNA7_PICGU ;  A3GGU3, BNA7_PICST ;
DR   A7TJ85, BNA7_VANPO ;  Q04066, BNA7_YEAST ;  A1TLB1, KYNB_ACIAC ;
DR   A0REX1, KYNB_BACAH ;  Q81PP9, KYNB_BACAN ;  Q736W4, KYNB_BACC1 ;
DR   A7GPY2, KYNB_BACCN ;  Q81CK1, KYNB_BACCR ;  Q63AJ1, KYNB_BACCZ ;
DR   Q6HHX8, KYNB_BACHK ;  A9VHP8, KYNB_BACWK ;  Q2KXW3, KYNB_BORA1 ;
DR   Q7WHE9, KYNB_BORBR ;  A9IU29, KYNB_BORPD ;  Q7VYS5, KYNB_BORPE ;
DR   B1YVH0, KYNB_BURA4 ;  Q1BU36, KYNB_BURCA ;  B1JXI7, KYNB_BURCC ;
DR   A0KA00, KYNB_BURCH ;  B4E9I9, KYNB_BURCJ ;  Q0BCE2, KYNB_BURCM ;
DR   A9AGH3, KYNB_BURM1 ;  A3MHE3, KYNB_BURM7 ;  A2S926, KYNB_BURM9 ;
DR   Q62M97, KYNB_BURMA ;  A1V195, KYNB_BURMS ;  A3NS57, KYNB_BURP0 ;
DR   Q3JVD6, KYNB_BURP1 ;  A3N6H4, KYNB_BURP6 ;  B2JDS4, KYNB_BURP8 ;
DR   B2SY84, KYNB_BURPP ;  Q63WP3, KYNB_BURPS ;  Q39DG4, KYNB_BURS3 ;
DR   Q2T0N2, KYNB_BURTA ;  A4JHD7, KYNB_BURVG ;  Q13UP0, KYNB_BURXL ;
DR   Q0K7X9, KYNB_CUPNH ;  Q474J5, KYNB_CUPPJ ;  B3R5Q1, KYNB_CUPTR ;
DR   Q1IY56, KYNB_DEIGD ;  A9BVE1, KYNB_DELAS ;  Q2N5X0, KYNB_ERYLH ;
DR   A4IT60, KYNB_GEOTN ;  Q0APM5, KYNB_MARMM ;  A1VRN9, KYNB_POLNA ;
DR   Q126P9, KYNB_POLSJ ;  A6V681, KYNB_PSEA7 ;  Q02LM8, KYNB_PSEAB ;
DR   Q9I234, KYNB_PSEAE ;  Q4KIP4, KYNB_PSEF5 ;  Q84HF4, KYNB_PSEFL ;
DR   P0C8P4, KYNB_RALME ;  B2U7J9, KYNB_RALPJ ;  Q8Y1D0, KYNB_RALSO ;
DR   Q2S2F5, KYNB_SALRD ;  Q1GTB8, KYNB_SPHAL ;
//
ID   3.5.1.10
DE   Formyltetrahydrofolate deformylase.
AN   Formyl-FH(4) hydrolase.
AN   Formyltetrahydrofolate hydrolase.
CA   10-formyltetrahydrofolate + H(2)O = formate + tetrahydrofolate.
DR   O34990, PURU_BACSU ;  Q46339, PURU_CORS1 ;  P0A440, PURU_ECOL6 ;
DR   P37051, PURU_ECOLI ;  Q03432, PURU_HAEIN ;  P0A5T7, PURU_MYCBO ;
DR   P0A5T6, PURU_MYCTU ;  P0A441, PURU_SHIFL ;  Q55135, PURU_SYNY3 ;
//
ID   3.5.1.11
DE   Penicillin amidase.
AN   Penicillin acylase.
CA   Penicillin + H(2)O = a carboxylate + 6-aminopenicillanate.
DR   P15558, PAC2_PSES3 ;  P31956, PAC_ARTVI  ;  Q60136, PAC_BACME  ;
DR   P06875, PAC_ECOLX  ;  P07941, PAC_KLUCI  ;  P12256, PAC_LYSSH  ;
//
ID   3.5.1.12
DE   Biotinidase.
AN   Biotinase.
CA   Biotin amide + H(2)O = biotin + NH(3).
CC   -!- Also acts on biotin esters.
PR   PROSITE; PDOC50263;
DR   A6QQ07, BTD_BOVIN  ;  P43251, BTD_HUMAN  ;  Q8CIF4, BTD_MOUSE  ;
DR   Q5FVF9, BTD_RAT    ;  Q8AV84, BTD_TAKRU  ;
//
ID   3.5.1.13
DE   Aryl-acylamidase.
CA   An anilide + H(2)O = a carboxylate + aniline.
CC   -!- Also acts on 4-substituted anilides.
DR   P80008, ARYC_NOCGL ;
//
ID   3.5.1.14
DE   Aminoacylase.
AN   Acylase I.
AN   Aminoacylase I.
AN   Benzamidase.
AN   Dehydropeptidase II.
AN   Hippuricase.
AN   Histozyme.
CA   An N-acyl-L-amino acid + H(2)O = a carboxylate + an L-amino acid.
CC   -!- Wide specificity; also hydrolyzes dehydropeptides.
CC   -!- Used in separating D- and L- amino acids.
PR   PROSITE; PDOC00613;
DR   Q6AYS7, ACY1A_RAT  ;  Q6PTT0, ACY1B_RAT  ;  Q55DP8, ACY1_DICDI ;
DR   Q03154, ACY1_HUMAN ;  Q99JW2, ACY1_MOUSE ;  P37111, ACY1_PIG   ;
DR   Q5RFB0, ACY1_PONAB ;  P37356, AMAA_BACTR ;  P37112, AMAA_GEOSE ;
//
ID   3.5.1.15
DE   Aspartoacylase.
AN   Aminoacylase II.
CA   N-acyl-L-aspartate + H(2)O = a carboxylate + L-aspartate.
DR   P46446, ACY2_BOVIN ;  A8KB34, ACY2_DANRE ;  P45381, ACY2_HUMAN ;
DR   Q60HH2, ACY2_MACFA ;  Q8R3P0, ACY2_MOUSE ;  B1PK17, ACY2_PIG   ;
DR   Q5R9E0, ACY2_PONAB ;  Q9R1T5, ACY2_RAT   ;  Q28C61, ACY2_XENTR ;
DR   B0C2K7, ASPA_ACAM1 ;  Q3MC79, ASPA_ANAVT ;  Q8YQC1, ASPA_NOSS1 ;
DR   A3PAU1, ASPA_PROM0 ;  A2C055, ASPA_PROM1 ;  A8G2N0, ASPA_PROM2 ;
DR   A2BUK0, ASPA_PROM5 ;  Q31CV9, ASPA_PROM9 ;  P72208, ASPA_PROMA ;
DR   Q7V5L6, ASPA_PROMM ;  P59830, ASPA_PROMP ;  A2BP19, ASPA_PROMS ;
DR   Q46HE9, ASPA_PROMT ;  P59829, ASPA_SYNPX ;  Q3AV13, ASPA_SYNS9 ;
DR   Q3AM91, ASPA_SYNSC ;  P73211, ASPA_SYNY3 ;  Q10VR3, ASPA_TRIEI ;
//
ID   3.5.1.16
DE   Acetylornithine deacetylase.
AN   Acetylornithinase.
AN   N-acetylornithinase.
CA   N(2)-acetyl-L-ornithine + H(2)O = acetate + L-ornithine.
CC   -!- Also hydrolyzes N-acetylmethionine.
PR   PROSITE; PDOC00613;
DR   B6EMN5, ARGE_ALISL ;  B8D8K5, ARGE_BUCA5 ;  P57155, ARGE_BUCAI ;
DR   P59085, ARGE_BUCAP ;  B8D6V9, ARGE_BUCAT ;  P54638, ARGE_DICDI ;
DR   A7ZUH5, ARGE_ECO24 ;  B7UNT3, ARGE_ECO27 ;  B7MI93, ARGE_ECO45 ;
DR   B7LA57, ARGE_ECO55 ;  Q8X742, ARGE_ECO57 ;  B5Z059, ARGE_ECO5E ;
DR   B7NU43, ARGE_ECO7I ;  B7MR48, ARGE_ECO81 ;  B7M711, ARGE_ECO8A ;
DR   C5A0C3, ARGE_ECOBW ;  B1XBC2, ARGE_ECODH ;  A8A765, ARGE_ECOHS ;
DR   Q0TAA3, ARGE_ECOL5 ;  Q8FB97, ARGE_ECOL6 ;  B1IVC1, ARGE_ECOLC ;
DR   P23908, ARGE_ECOLI ;  B7NFQ7, ARGE_ECOLU ;  B6I5H3, ARGE_ECOSE ;
DR   B1LNR7, ARGE_ECOSM ;  C5BC62, ARGE_EDWI9 ;  A4WG54, ARGE_ENT38 ;
DR   Q6DAR2, ARGE_ERWCT ;  B2VGA3, ARGE_ERWT9 ;  B7LUN8, ARGE_ESCF3 ;
DR   B5XZ19, ARGE_KLEP3 ;  P13440, ARGE_LEPBI ;  Q9K4Z2, ARGE_MORAB ;
DR   Q9K4Z7, ARGE_MORPR ;  O68873, ARGE_MYXXA ;  Q9CLT9, ARGE_PASMU ;
DR   C6DI82, ARGE_PECCP ;  Q7MYD5, ARGE_PHOLL ;  B4F192, ARGE_PROMH ;
DR   B5F0U6, ARGE_SALA4 ;  A9MI13, ARGE_SALAR ;  Q57H96, ARGE_SALCH ;
DR   B5FPX2, ARGE_SALDC ;  B5QXQ2, ARGE_SALEP ;  B5RF48, ARGE_SALG2 ;
DR   B4TCQ3, ARGE_SALHS ;  B4T0W8, ARGE_SALNS ;  Q5PK76, ARGE_SALPA ;
DR   A9N0G7, ARGE_SALPB ;  B5BJN1, ARGE_SALPK ;  B4TQH3, ARGE_SALSV ;
DR   Q8Z308, ARGE_SALTI ;  Q8ZKL9, ARGE_SALTY ;  B2TWF2, ARGE_SHIB3 ;
DR   Q31U31, ARGE_SHIBS ;  Q32AB8, ARGE_SHIDS ;  Q0SY37, ARGE_SHIF8 ;
DR   P59600, ARGE_SHIFL ;  Q3YV19, ARGE_SHISS ;  A5F4Z7, ARGE_VIBC3 ;
DR   Q9KNT5, ARGE_VIBCH ;  C3LRV6, ARGE_VIBCM ;  Q5E2E4, ARGE_VIBF1 ;
DR   B5FBP7, ARGE_VIBFM ;  A7MXC2, ARGE_VIBHB ;  P59601, ARGE_VIBPA ;
DR   B7VLL4, ARGE_VIBSL ;  Q8DCN1, ARGE_VIBVU ;  Q7MH69, ARGE_VIBVY ;
DR   A7FCZ8, ARGE_YERP3 ;  Q8ZA85, ARGE_YERPE ;  Q66G73, ARGE_YERPS ;
//
ID   3.5.1.17
DE   Acyl-lysine deacylase.
AN   Epsilon-lysine acylase.
CA   N(6)-acyl-L-lysine + H(2)O = a carboxylate + L-lysine.
//
ID   3.5.1.18
DE   Succinyl-diaminopimelate desuccinylase.
CA   N-succinyl-LL-2,6-diaminoheptanedioate + H(2)O = succinate + LL-2,6-
CA   diaminoheptanedioate.
PR   PROSITE; PDOC00613;
DR   B4RZS0, DAPE1_ALTMD;  A3QE30, DAPE1_SHELP;  Q1GC88, DAPE1_SILST;
DR   B4RSS7, DAPE2_ALTMD;  A3QGR1, DAPE2_SHELP;  Q1GMM6, DAPE2_SILST;
DR   A1TQ19, DAPE_ACIAC ;  Q6FE14, DAPE_ACIAD ;  B7GXA3, DAPE_ACIB3 ;
DR   B7I842, DAPE_ACIB5 ;  B2HY23, DAPE_ACIBC ;  B0VRY3, DAPE_ACIBS ;
DR   A3M8H2, DAPE_ACIBT ;  B0V4V8, DAPE_ACIBY ;  A5FYQ7, DAPE_ACICJ ;
DR   B9MJL1, DAPE_ACIET ;  B7JBS5, DAPE_ACIF2 ;  B5ES53, DAPE_ACIF5 ;
DR   A1W7M0, DAPE_ACISJ ;  A3N3G9, DAPE_ACTP2 ;  B3H2U3, DAPE_ACTP7 ;
DR   B0BTF3, DAPE_ACTPJ ;  A6VMI0, DAPE_ACTSZ ;  A0KIB5, DAPE_AERHH ;
DR   A4SPS7, DAPE_AERS4 ;  B9J8D0, DAPE_AGRRK ;  A9CKC4, DAPE_AGRT5 ;
DR   B9JZL9, DAPE_AGRVS ;  Q0VQG3, DAPE_ALCBS ;  Q0A7H5, DAPE_ALHEH ;
DR   B6EJS8, DAPE_ALISL ;  B9KHC9, DAPE_ANAMF ;  Q5P9A2, DAPE_ANAMM ;
DR   A8ETY6, DAPE_ARCB4 ;  Q5NYT7, DAPE_AROAE ;  A8IMH3, DAPE_AZOC5 ;
DR   A1K719, DAPE_AZOSB ;  A1UUD2, DAPE_BARBK ;  Q6G567, DAPE_BARHE ;
DR   Q6G1H9, DAPE_BARQU ;  A9ILD7, DAPE_BART1 ;  B2IDW3, DAPE_BEII9 ;
DR   Q7VRT2, DAPE_BLOFL ;  Q492F7, DAPE_BLOPB ;  Q2L2J6, DAPE_BORA1 ;
DR   Q7WKC6, DAPE_BORBR ;  Q7W8Y3, DAPE_BORPA ;  A9IR81, DAPE_BORPD ;
DR   Q7VXJ5, DAPE_BORPE ;  Q89BP2, DAPE_BRAJA ;  A5ESQ3, DAPE_BRASB ;
DR   A4YLC3, DAPE_BRASO ;  B2SC17, DAPE_BRUA1 ;  Q2YJQ6, DAPE_BRUA2 ;
DR   Q576T3, DAPE_BRUAB ;  A9MCV6, DAPE_BRUC2 ;  C0RMH0, DAPE_BRUMB ;
DR   Q8YDB0, DAPE_BRUME ;  A5VVT7, DAPE_BRUO2 ;  A9WW41, DAPE_BRUSI ;
DR   Q8FV22, DAPE_BRUSU ;  B8D8P7, DAPE_BUCA5 ;  P57196, DAPE_BUCAI ;
DR   Q8KA25, DAPE_BUCAP ;  B8D701, DAPE_BUCAT ;  Q89AY1, DAPE_BUCBP ;
DR   Q058B2, DAPE_BUCCC ;  B1YSH9, DAPE_BURA4 ;  Q1BHJ5, DAPE_BURCA ;
DR   B1JUG2, DAPE_BURCC ;  A0K8F6, DAPE_BURCH ;  B4ECP3, DAPE_BURCJ ;
DR   Q0BE03, DAPE_BURCM ;  A9AHS8, DAPE_BURM1 ;  A3MKV8, DAPE_BURM7 ;
DR   A2SB58, DAPE_BURM9 ;  Q62JB1, DAPE_BURMA ;  A1V584, DAPE_BURMS ;
DR   A3NWP5, DAPE_BURP0 ;  Q3JR15, DAPE_BURP1 ;  A3NAW2, DAPE_BURP6 ;
DR   B2JID9, DAPE_BURP8 ;  B2T5K8, DAPE_BURPP ;  Q63T00, DAPE_BURPS ;
DR   Q39F31, DAPE_BURS3 ;  Q2SX11, DAPE_BURTA ;  A4JF88, DAPE_BURVG ;
DR   Q13XA2, DAPE_BURXL ;  A7ZFC1, DAPE_CAMC1 ;  A7GX37, DAPE_CAMC5 ;
DR   A0RNM0, DAPE_CAMFF ;  A7I005, DAPE_CAMHC ;  A8FMA1, DAPE_CAMJ8 ;
DR   A7H2V9, DAPE_CAMJD ;  Q0P9K4, DAPE_CAMJE ;  A1W038, DAPE_CAMJJ ;
DR   Q5HU53, DAPE_CAMJR ;  B9KD35, DAPE_CAMLR ;  B8GYE7, DAPE_CAUCN ;
DR   Q9ABF3, DAPE_CAUCR ;  B0T134, DAPE_CAUSK ;  B3PBB9, DAPE_CELJU ;
DR   Q1R039, DAPE_CHRSD ;  Q7NY19, DAPE_CHRVO ;  A8ADB6, DAPE_CITK8 ;
DR   Q47Z95, DAPE_COLP3 ;  Q59284, DAPE_CORGL ;  B6J929, DAPE_COXB1 ;
DR   B6J120, DAPE_COXB2 ;  A9KC82, DAPE_COXBN ;  A9NCE9, DAPE_COXBR ;
DR   Q83DN2, DAPE_COXBU ;  Q0KA02, DAPE_CUPNH ;  Q470C3, DAPE_CUPPJ ;
DR   B3R2D1, DAPE_CUPTR ;  Q47FB0, DAPE_DECAR ;  A9BZY6, DAPE_DELAS ;
DR   A8LJT5, DAPE_DINSH ;  A7ZPR5, DAPE_ECO24 ;  B7UGM1, DAPE_ECO27 ;
DR   B7MHW4, DAPE_ECO45 ;  B7LCK7, DAPE_ECO55 ;  Q8XBE0, DAPE_ECO57 ;
DR   B5Z008, DAPE_ECO5E ;  B7NQK9, DAPE_ECO7I ;  B7M7H2, DAPE_ECO8A ;
DR   C4ZX46, DAPE_ECOBW ;  B1XAE3, DAPE_ECODH ;  A8A2W3, DAPE_ECOHS ;
DR   A1ADX7, DAPE_ECOK1 ;  Q0TF05, DAPE_ECOL5 ;  Q8FF82, DAPE_ECOL6 ;
DR   B1IWI8, DAPE_ECOLC ;  P0AED7, DAPE_ECOLI ;  B7N653, DAPE_ECOLU ;
DR   B6I539, DAPE_ECOSE ;  B1LNC1, DAPE_ECOSM ;  Q1R8Q6, DAPE_ECOUT ;
DR   Q3YT10, DAPE_EHRCJ ;  Q2GHW1, DAPE_EHRCR ;  Q5FFA0, DAPE_EHRRG ;
DR   Q5HC82, DAPE_EHRRW ;  A4WD51, DAPE_ENT38 ;  A7ML10, DAPE_ENTS8 ;
DR   Q6D7N4, DAPE_ERWCT ;  B2VE50, DAPE_ERWT9 ;  Q2N7X8, DAPE_ERYLH ;
DR   B7LKH0, DAPE_ESCF3 ;  A9HKR2, DAPE_GLUDA ;  Q5FPX5, DAPE_GLUOX ;
DR   Q0BUB7, DAPE_GRABC ;  Q7VNB3, DAPE_HAEDU ;  Q4QP83, DAPE_HAEI8 ;
DR   A5UB44, DAPE_HAEIE ;  A5UFQ7, DAPE_HAEIG ;  P44514, DAPE_HAEIN ;
DR   B8F824, DAPE_HAEPS ;  Q0I1X3, DAPE_HAES1 ;  B0UT10, DAPE_HAES2 ;
DR   Q2SBP0, DAPE_HAHCH ;  A1WX26, DAPE_HALHL ;  Q17VU8, DAPE_HELAH ;
DR   Q7VF72, DAPE_HELHP ;  B6JKE4, DAPE_HELP2 ;  B5Z9Y1, DAPE_HELPG ;
DR   Q1CUU2, DAPE_HELPH ;  Q9ZMM0, DAPE_HELPJ ;  B2US41, DAPE_HELPS ;
DR   O25002, DAPE_HELPY ;  A4G4Q7, DAPE_HERAR ;  Q5QTZ3, DAPE_IDILO ;
DR   A6SZR5, DAPE_JANMA ;  Q28VJ1, DAPE_JANSC ;  B5XVN4, DAPE_KLEP3 ;
DR   A6TC94, DAPE_KLEP7 ;  C1D8X7, DAPE_LARHH ;  Q5X6L7, DAPE_LEGPA ;
DR   A5IG28, DAPE_LEGPC ;  Q5ZX46, DAPE_LEGPH ;  Q5WY21, DAPE_LEGPL ;
DR   B1Y6E7, DAPE_LEPCP ;  Q2W0E7, DAPE_MAGSA ;  A0L3N2, DAPE_MAGSM ;
DR   Q65US9, DAPE_MANSM ;  A1U3R0, DAPE_MARAV ;  Q0ASJ5, DAPE_MARMM ;
DR   A6VUR6, DAPE_MARMS ;  Q11LD2, DAPE_MESSB ;  B7KVW2, DAPE_METC4 ;
DR   Q608D9, DAPE_METCA ;  A9W376, DAPE_METEP ;  Q1H051, DAPE_METFK ;
DR   B8IFQ0, DAPE_METNO ;  B1ZGA7, DAPE_METPB ;  A2SGS4, DAPE_METPP ;
DR   B1M6P0, DAPE_METRJ ;  B0UP37, DAPE_METS4 ;  B8ELJ6, DAPE_METSB ;
DR   B9L8Q2, DAPE_NAUPA ;  Q5F812, DAPE_NEIG1 ;  B4RKY8, DAPE_NEIG2 ;
DR   A9M0W6, DAPE_NEIM0 ;  A1ISU7, DAPE_NEIMA ;  Q9JYL2, DAPE_NEIMB ;
DR   A1KUW7, DAPE_NEIMF ;  Q0ADY0, DAPE_NITEC ;  Q82XY4, DAPE_NITEU ;
DR   Q1QH74, DAPE_NITHX ;  Q2Y7X4, DAPE_NITMU ;  Q3J9B0, DAPE_NITOC ;
DR   A6Q4D7, DAPE_NITSB ;  Q3SN25, DAPE_NITWN ;  Q2GAU5, DAPE_NOVAD ;
DR   A6WYL3, DAPE_OCHA4 ;  B6JJP4, DAPE_OLICO ;  A5CCZ1, DAPE_ORITB ;
DR   B3CRZ3, DAPE_ORITI ;  A1B5Y2, DAPE_PARDP ;  A7HPQ6, DAPE_PARL1 ;
DR   Q9CM22, DAPE_PASMU ;  Q4FNF5, DAPE_PELUB ;  B4RDU4, DAPE_PHEZH ;
DR   Q7N3J4, DAPE_PHOLL ;  Q6LTW8, DAPE_PHOPR ;  A1VN92, DAPE_POLNA ;
DR   B1XTT6, DAPE_POLNS ;  Q12C18, DAPE_POLSJ ;  A4SYV9, DAPE_POLSQ ;
DR   B4EY70, DAPE_PROMH ;  Q48F49, DAPE_PSE14 ;  Q15TS8, DAPE_PSEA6 ;
DR   A6V936, DAPE_PSEA7 ;  B7UX27, DAPE_PSEA8 ;  Q02IY2, DAPE_PSEAB ;
DR   Q9I4H5, DAPE_PSEAE ;  Q1I614, DAPE_PSEE4 ;  Q4KHI7, DAPE_PSEF5 ;
DR   Q3IL20, DAPE_PSEHT ;  A4XWV4, DAPE_PSEMY ;  A5W863, DAPE_PSEP1 ;
DR   Q3KHC5, DAPE_PSEPF ;  B0KS83, DAPE_PSEPG ;  Q88MP5, DAPE_PSEPK ;
DR   B1JBS2, DAPE_PSEPW ;  Q886Q4, DAPE_PSESM ;  Q6VE94, DAPE_PSESY ;
DR   Q4ZWU0, DAPE_PSEU2 ;  A4VMY9, DAPE_PSEU5 ;  Q4FU86, DAPE_PSYA2 ;
DR   Q1QDC1, DAPE_PSYCK ;  A1SXF9, DAPE_PSYIN ;  A5WD56, DAPE_PSYWF ;
DR   Q1LNH3, DAPE_RALME ;  B2UAZ1, DAPE_RALPJ ;  Q8XZK5, DAPE_RALSO ;
DR   Q2KD47, DAPE_RHIEC ;  Q1MM75, DAPE_RHIL3 ;  Q98D57, DAPE_RHILO ;
DR   B5ZN23, DAPE_RHILW ;  Q92SH1, DAPE_RHIME ;  B6IPH8, DAPE_RHOCS ;
DR   Q21WT4, DAPE_RHOFD ;  Q2J2C3, DAPE_RHOP2 ;  Q07TX3, DAPE_RHOP5 ;
DR   Q6NC49, DAPE_RHOPA ;  Q21B56, DAPE_RHOPB ;  Q13F22, DAPE_RHOPS ;
DR   B3QCH4, DAPE_RHOPT ;  Q2RNM1, DAPE_RHORT ;  A3PNH5, DAPE_RHOS1 ;
DR   Q3IYS2, DAPE_RHOS4 ;  A4WNJ6, DAPE_RHOS5 ;  B9KP62, DAPE_RHOSK ;
DR   C3PM12, DAPE_RICAE ;  A8GQ98, DAPE_RICAH ;  A8GYC8, DAPE_RICB8 ;
DR   Q1RGL3, DAPE_RICBR ;  A8F095, DAPE_RICCK ;  Q92FY0, DAPE_RICCN ;
DR   Q4UJR2, DAPE_RICFE ;  A8F303, DAPE_RICM5 ;  Q9ZC93, DAPE_RICPR ;
DR   C4K2X8, DAPE_RICPU ;  B0BVN5, DAPE_RICRO ;  A8GU44, DAPE_RICRS ;
DR   Q68VN9, DAPE_RICTY ;  Q16DM9, DAPE_ROSDO ;  A1AVU9, DAPE_RUTMC ;
DR   Q21HG2, DAPE_SACD2 ;  B5F0L0, DAPE_SALA4 ;  A9MHQ8, DAPE_SALAR ;
DR   Q57LM8, DAPE_SALCH ;  B5FQH3, DAPE_SALDC ;  B5R4J0, DAPE_SALEP ;
DR   B5RCV3, DAPE_SALG2 ;  B4TD58, DAPE_SALHS ;  B4T0L0, DAPE_SALNS ;
DR   Q5PLR5, DAPE_SALPA ;  A9N2Z9, DAPE_SALPB ;  C0PYS5, DAPE_SALPC ;
DR   B5BB22, DAPE_SALPK ;  B4TR55, DAPE_SALSV ;  Q8Z4S2, DAPE_SALTI ;
DR   Q8ZN75, DAPE_SALTY ;  A8GHK9, DAPE_SERP5 ;  A1S647, DAPE_SHEAM ;
DR   B8EA23, DAPE_SHEB2 ;  A3D547, DAPE_SHEB5 ;  A6WNV3, DAPE_SHEB8 ;
DR   A9L3M8, DAPE_SHEB9 ;  Q12N78, DAPE_SHEDO ;  Q083F0, DAPE_SHEFN ;
DR   B0TVI4, DAPE_SHEHH ;  Q8EEB6, DAPE_SHEON ;  A8H424, DAPE_SHEPA ;
DR   A4Y7B1, DAPE_SHEPC ;  B8CMP0, DAPE_SHEPW ;  A0KWH4, DAPE_SHESA ;
DR   A8FW04, DAPE_SHESH ;  Q0HJ36, DAPE_SHESM ;  Q0HUU6, DAPE_SHESR ;
DR   A1RJ78, DAPE_SHESW ;  B1KDS3, DAPE_SHEWM ;  B2TXP7, DAPE_SHIB3 ;
DR   Q31Y20, DAPE_SHIBS ;  Q32D98, DAPE_SHIDS ;  Q0T246, DAPE_SHIF8 ;
DR   P0AED8, DAPE_SHIFL ;  Q3YZ81, DAPE_SHISS ;  Q5LN80, DAPE_SILPO ;
DR   A6U5J1, DAPE_SINMW ;  Q2NS82, DAPE_SODGM ;  Q1GRJ2, DAPE_SPHAL ;
DR   A5VCF0, DAPE_SPHWW ;  Q931I4, DAPE_STAAM ;  Q99SN6, DAPE_STAAN ;
DR   Q6GF48, DAPE_STAAR ;  Q6G7T6, DAPE_STAAS ;  Q8NVL7, DAPE_STAAW ;
DR   Q5HKI1, DAPE_STAEQ ;  Q8CQC2, DAPE_STAES ;  B4SQ35, DAPE_STRM5 ;
DR   B2FIC0, DAPE_STRMK ;  Q30QK9, DAPE_SULDN ;  A6Q7J0, DAPE_SULNB ;
DR   C5BQE9, DAPE_TERTT ;  Q31G37, DAPE_THICR ;  Q3SJE0, DAPE_THIDA ;
DR   B8GPR9, DAPE_THISH ;  C4LDG0, DAPE_TOLAT ;  C5CLT2, DAPE_VARPS ;
DR   A1WEL1, DAPE_VEREI ;  A5CXE9, DAPE_VESOH ;  A5F6B5, DAPE_VIBC3 ;
DR   Q9KQ52, DAPE_VIBCH ;  C3LPF7, DAPE_VIBCM ;  Q5E3I7, DAPE_VIBF1 ;
DR   B5FGX0, DAPE_VIBFM ;  A7MY37, DAPE_VIBHB ;  Q87MI6, DAPE_VIBPA ;
DR   B7VIL8, DAPE_VIBSL ;  Q8DBA6, DAPE_VIBVU ;  Q7MIL6, DAPE_VIBVY ;
DR   Q8D2S2, DAPE_WIGBR ;  Q73GZ0, DAPE_WOLPM ;  B3CLN1, DAPE_WOLPP ;
DR   Q7MSC2, DAPE_WOLSU ;  Q5GS68, DAPE_WOLTR ;  Q8PMJ5, DAPE_XANAC ;
DR   Q3BVJ3, DAPE_XANC5 ;  Q4USS4, DAPE_XANC8 ;  B0RW53, DAPE_XANCB ;
DR   Q8PAU0, DAPE_XANCP ;  Q2P492, DAPE_XANOM ;  B2SQY5, DAPE_XANOP ;
DR   Q5H1C8, DAPE_XANOR ;  A7IH44, DAPE_XANP2 ;  B2I6B4, DAPE_XYLF2 ;
DR   Q9PH30, DAPE_XYLFA ;  B0U296, DAPE_XYLFM ;  Q87F49, DAPE_XYLFT ;
DR   A1JL17, DAPE_YERE8 ;  A7FG57, DAPE_YERP3 ;  Q1C5R3, DAPE_YERPA ;
DR   B2K985, DAPE_YERPB ;  Q7CJI9, DAPE_YERPE ;  A9R2H7, DAPE_YERPG ;
DR   Q1CK18, DAPE_YERPN ;  A4TMM3, DAPE_YERPP ;  Q668G5, DAPE_YERPS ;
DR   B1JSH5, DAPE_YERPY ;  Q5NM04, DAPE_ZYMMO ;
//
ID   3.5.1.19
DE   Nicotinamidase.
AN   NAMase.
AN   Nicotine deamidase.
CA   Nicotinamide + H(2)O = nicotinate + NH(3).
DR   Q9USS0, PNC1_SCHPO ;  P53184, PNC1_YEAST ;  P21369, PNCA_ECOLI ;
//
ID   3.5.1.20
DE   Citrullinase.
CA   L-citrulline + H(2)O = L-ornithine + CO(2) + NH(3).
//
ID   3.5.1.21
DE   N-acetyl-beta-alanine deacetylase.
CA   N-acetyl-beta-alanine + H(2)O = acetate + beta-alanine.
//
ID   3.5.1.22
DE   Pantothenase.
CA   (R)-pantothenate + H(2)O = (R)-pantoate + beta-alanine.
//
ID   3.5.1.23
DE   Ceramidase.
AN   Acylsphingosine deacylase.
CA   N-acylsphingosine + H(2)O = a carboxylate + sphingosine.
DR   Q60WT2, ACASE_CAEBR;  O45145, ACASE_CAEEL;  Q9VIP7, ACASE_DROME;
DR   Q568I2, ACER1_DANRE;  Q8TDN7, ACER1_HUMAN;  Q8R4X1, ACER1_MOUSE;
DR   Q5QJU3, ACER2_HUMAN;  Q8VD53, ACER2_MOUSE;  P0C7U2, ASA2C_HUMAN;
DR   Q17QB3, ASAH1_BOVIN;  O45686, ASAH1_CAEEL;  Q13510, ASAH1_HUMAN;
DR   Q60HH4, ASAH1_MACFA;  Q9WV54, ASAH1_MOUSE;  A5A6P2, ASAH1_PANTR;
DR   Q6P7S1, ASAH1_RAT  ;  Q5W7F1, ASAH2_DANRE;  Q9NR71, ASAH2_HUMAN;
DR   Q9JHE3, ASAH2_MOUSE;  Q91XT9, ASAH2_RAT  ;  Q304B9, NCASE_ARATH;
DR   Q9VA70, NCASE_DROME;  Q29C43, NCASE_DROPS;  Q0JL46, NCASE_ORYSJ;
DR   Q9I596, NCASE_PSEAE;  Q54BK2, NCSEA_DICDI;  Q55G11, NCSEB_DICDI;
//
ID   3.5.1.24
DE   Choloylglycine hydrolase.
AN   Bile salt hydrolase.
AN   Glycocholase.
CA   3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholan-24-oylglycine + H(2)O =
CA   3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + glycine.
CC   -!- Also acts on the 3-alpha,12-alpha-dihydroxy-derivative, and on
CC       choloyl-taurine.
DR   P54965, CBH_CLOPE  ;  Q06115, CBH_LACPL  ;
//
ID   3.5.1.25
DE   N-acetylglucosamine-6-phosphate deacetylase.
CA   N-acetyl-D-glucosamine 6-phosphate + H(2)O = D-glucosamine 6-phosphate +
CA   acetate.
CC   -!- Formerly EC 3.5.1.80.
DR   O34450, NAGA_BACSU ;  A7MBC0, NAGA_BOVIN ;  P34480, NAGA_CAEEL ;
DR   Q6P0U0, NAGA_DANRE ;  Q9VR81, NAGA_DROME ;  P0AF19, NAGA_ECO57 ;
DR   P0AF18, NAGA_ECOLI ;  P44537, NAGA_HAEIN ;  Q9Y303, NAGA_HUMAN ;
DR   Q84F86, NAGA_LYSSH ;  Q8JZV7, NAGA_MOUSE ;  Q5BJY6, NAGA_RAT   ;
DR   O32445, NAGA_VIBCH ;  P96166, NAGA_VIBFU ;
//
ID   3.5.1.26
DE   N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase.
AN   Aspartylglucosaminidase.
AN   Aspartylglucosylaminase.
AN   Aspartylglucosylamine deaspartylase.
AN   Aspartylglucosylaminidase.
AN   Aspartylglycosylamine amidohydrolase.
AN   Beta-aspartylglucosylamine amidohydrolase.
AN   Glucosylamidase.
AN   Glycosylasparaginase.
AN   N-aspartyl-beta-glucosaminidase.
CA   N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H(2)O = N-acetyl-beta-
CA   D-glucosaminylamine + L-aspartate.
CC   -!- Acts only on asparagine-oligosaccharides containing one amino acid,
CC       i.e. the asparagine has free alpha-amino and alpha-carboxyl groups
CC       (cf. EC 3.5.1.52).
CC   -!- Formerly EC 3.5.1.37.
DR   B3N6Y7, ASPG1_DROER;  B4JVW6, ASPG1_DROGR;  Q8MR45, ASPG1_DROME;
DR   B4GGF2, ASPG1_DROPE;  Q28Y14, ASPG1_DROPS;  B4HT15, ASPG1_DROSE;
DR   B4QHB1, ASPG1_DROSI;  B4NWI1, ASPG1_DROYA;  P83451, ASPG_ASOTA ;
DR   Q21697, ASPG_CAEEL ;  Q47898, ASPG_ELIMR ;  P20933, ASPG_HUMAN ;
DR   Q4R6C4, ASPG_MACFA ;  Q64191, ASPG_MOUSE ;  P30918, ASPG_PIG   ;
DR   P30919, ASPG_RAT   ;  O02467, ASPG_SPOFR ;
//
ID   3.5.1.27
DE   N-formylmethionylaminoacyl-tRNA deformylase.
CA   N-formyl-L-methionylaminoacyl-tRNA + H(2)O = formate +
CA   L-methionylaminoacyl-tRNA.
//
ID   3.5.1.28
DE   N-acetylmuramoyl-L-alanine amidase.
CA   Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid
CA   residues in certain cell-wall glycopeptides.
CC   -!- Formerly EC 3.4.12.5, EC 3.4.17.7 and EC 3.4.19.10.
PR   PROSITE; PDOC00737;
DR   Q38653, ALYS_BPA51 ;  O03979, ALYS_BPDP1 ;  P32762, ALYS_BPHB3 ;
DR   Q38135, ALYS_BPR1T ;  P06653, ALYS_STRPN ;  P36548, AMIA_ECOLI ;
DR   P33772, AMIA_SALTY ;  P57638, AMIB_BUCAI ;  Q8K908, AMIB_BUCAP ;
DR   Q89A33, AMIB_BUCBP ;  P26365, AMIB_ECOLI ;  P44493, AMIB_HAEIN ;
DR   P26366, AMIB_SALTY ;  P63884, AMIC_ECOL6 ;  P63883, AMIC_ECOLI ;
DR   Q9K0V3, AMIC_NEIMB ;  P75820, AMID_ECOLI ;  P82974, AMPD_CITFR ;
DR   P13016, AMPD_ECOLI ;  P82973, AMPD_ENTCL ;  P44624, AMPD_HAEIN ;
DR   E1W818, AMPD_SALTS ;  P0CL03, AMPD_SALTY ;  A7X0T9, ATL_STAA1  ;
DR   Q2FZK7, ATL_STAA8  ;  Q5HH31, ATL_STAAC  ;  Q931U5, ATL_STAAM  ;
DR   Q99V41, ATL_STAAN  ;  Q6GI31, ATL_STAAR  ;  Q6GAG0, ATL_STAAS  ;
DR   P0C5Z8, ATL_STAAU  ;  Q8NX96, ATL_STAAW  ;  O33635, ATL_STAEP  ;
DR   Q5HQB9, ATL_STAEQ  ;  Q8CPQ1, ATL_STAES  ;  O31982, BLYA_BACSU ;
DR   P81717, CWHA_ACHLY ;  P14892, CWLA_BACSP ;  P24808, CWLA_BACSU ;
DR   Q02114, CWLB_BACSU ;  Q06320, CWLC_BACSU ;  P50864, CWLD_BACSU ;
DR   P54450, CWLH_BACSU ;  P36550, CWLL_BACLI ;  P37134, CWLM_BACLI ;
DR   Q99125, CWLX_BACLI ;  P24556, LYTA_STAAU ;  P20331, NAAA_BPT3  ;
DR   P00806, NAAA_BPT7  ;  P85143, NAAA_LYSSP ;  Q8INK6, PGPLB_DROME;
DR   Q96PD5, PGRP2_HUMAN;  Q8VCS0, PGRP2_MOUSE;  Q866Y3, PGRP2_PIG  ;
DR   Q70PY2, PGSB1_DROME;  Q9VV96, PGSB2_DROME;  Q70PW6, PGSB2_DROSI;
DR   Q9V3B7, PGSC1_DROME;  Q70PU2, PGSC1_DROSI;  Q9V4X2, PGSC2_DROME;
DR   Q70PU1, PGSC2_DROSI;  Q2FJH7, SLE1_STAA3 ;  Q2G0U9, SLE1_STAA8 ;
DR   Q2YVT4, SLE1_STAAB ;  Q5HIL2, SLE1_STAAC ;  Q7A7E0, SLE1_STAAN ;
DR   Q6GJK9, SLE1_STAAR ;  Q6GC24, SLE1_STAAS ;  P0C1U7, SLE1_STAAU ;
DR   Q7A1T4, SLE1_STAAW ;  Q5HRU2, SLE1_STAEQ ;  Q8CMN2, SLE1_STAES ;
DR   Q4L3C1, SLE1_STAHJ ;  Q49UX4, SLE1_STAS1 ;  P39800, XLYA_BACSU ;
DR   O34391, XLYB_BACSU ;  Q92IC3, Y497_RICCN ;  O32041, YRVJ_BACSU ;
//
ID   3.5.1.29
DE   2-(acetamidomethylene)succinate hydrolase.
CA   2-(acetamidomethylene)succinate + 2 H(2)O = acetate + succinate
CA   semialdehyde + NH(3) + CO(2).
CC   -!- Involved in the degradation of pyridoxin in Pseudomonas.
//
ID   3.5.1.30
DE   5-aminopentanamidase.
AN   5-aminovaleramidase.
CA   5-aminopentanamide + H(2)O = 5-aminopentanoate + NH(3).
CC   -!- The enzyme from Pseudomonas putida also acts on 4-aminobutanamide
CC       and, more slowly, on 6-aminohexanamide.
//
ID   3.5.1.31
DE   Formylmethionine deformylase.
CA   N-formyl-L-methionine + H(2)O = formate + L-methionine.
//
ID   3.5.1.32
DE   Hippurate hydrolase.
AN   Benzoylglycine amidohydrolase.
AN   Hippuricase.
CA   Hippurate + H(2)O = benzoate + glycine.
CC   -!- Acts on various N-benzoylamino acids.
DR   P45493, HIPO_CAMJE ;
//
ID   3.5.1.33
DE   N-acetylglucosamine deacetylase.
CA   N-acetyl-D-glucosamine + H(2)O = D-glucosamine + acetate.
//
ID   3.5.1.34
DE   Transferred entry: 3.4.13.5.
//
ID   3.5.1.35
DE   D-glutaminase.
CA   D-glutamine + H(2)O = D-glutamate + NH(3).
//
ID   3.5.1.36
DE   N-methyl-2-oxoglutaramate hydrolase.
AN   5-hydroxy-N-methylpyroglutamate synthase.
CA   N-methyl-2-oxoglutaramate + H(2)O = 2-oxoglutarate + methylamine.
CC   -!- In the reverse reaction, the product cyclizes non-enzymically to
CC       2-hydroxy-N-methyl-5-oxoproline.
//
ID   3.5.1.37
DE   Transferred entry: 3.5.1.26.
//
ID   3.5.1.38
DE   Glutamin-(asparagin-)ase.
AN   Glutaminase-asparaginase.
AN   L-ASNase/L-GLNase.
AN   L-asparagine/L-glutamine amidohydrolase.
CA   (1) L-glutamine + H(2)O = L-glutamate + NH(3).
CA   (2) L-asparagine + H(2)O = L-aspartate + NH(3).
CC   -!- L-asparagine is hydrolyzed at 0.8 of the rate of L-glutamine.
CC   -!- The D-isomers are also hydrolyzed, more slowly.
PR   PROSITE; PDOC00132;
DR   P10172, ASPQ_ACIGL ;  P83712, ASPQ_DELAC ;  Q9I407, ASPQ_PSEAE ;
DR   O68897, ASPQ_PSEFA ;  Q88K39, ASPQ_PSEPK ;  P10182, ASPQ_PSES7 ;
//
ID   3.5.1.39
DE   Alkylamidase.
CA   N-methylhexanamide + H(2)O = hexanoate + methylamine.
CC   -!- The enzyme hydrolyzes N-monosubstituted and N,N-disubstituted amides,
CC       and there is some activity toward primary amides.
CC   -!- It has little or no activity toward short-chain substrates.
//
ID   3.5.1.40
DE   Acylagmatine amidase.
CA   Benzoylagmatine + H(2)O = benzoate + agmatine.
CC   -!- Also acts on acetylagmatine, propanoylagmatine and bleomycin B(2).
//
ID   3.5.1.41
DE   Chitin deacetylase.
CA   Chitin + H(2)O = chitosan + acetate.
CC   -!- Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues
CC       in chitin.
DR   O13842, CDA1_SCHPO ;  Q06702, CDA1_YEAST ;  Q06703, CDA2_YEAST ;
DR   P50325, CDA_AMYRO  ;  P0CP77, CDA_CRYNB  ;  P0CP76, CDA_CRYNJ  ;
DR   P82476, CDA_CRYNV  ;
//
ID   3.5.1.42
DE   Nicotinamide-nucleotide amidase.
CA   Beta-nicotinamide D-ribonucleotide + H(2)O = beta-nicotinate
CA   D-ribonucleotide + NH(3).
CC   -!- Also acts more slowly on beta-nicotinamide D-ribonucleoside.
//
ID   3.5.1.43
DE   Peptidyl-glutaminase.
AN   Peptidoglutaminase I.
CA   Alpha-N-peptidyl-L-glutamine + H(2)O = alpha-N-peptidyl-L-glutamate +
CA   NH(3).
CC   -!- Specific for the hydrolysis of the gamma-amide of glutamine
CC       substituted at the alpha-amino group, e.g., glycyl-L-glutamine,
CC       N-acetyl-L-glutamine and L-leucylglycyl-L-glutamine.
//
ID   3.5.1.44
DE   Protein-glutamine glutaminase.
AN   Glutaminylpeptide glutaminase.
AN   Peptidoglutaminase II.
CA   Protein L-glutamine + H(2)O = protein L-glutamate + NH(3).
CC   -!- Specific for the hydrolysis of the gamma-amide of glutamine
CC       substituted at the carboxyl position or both the alpha-amino and
CC       carboxyl positions, e.g., L-glutaminylglycine and L-phenylalanyl-L-
CC       glutaminylglycine.
DR   Q2INJ4, CHED1_ANADE;  Q2STS7, CHED1_BURTA;  Q7NZB2, CHED1_CHRVO;
DR   Q47I44, CHED1_DECAR;  Q39WQ8, CHED1_GEOMG;  Q74F83, CHED1_GEOSL;
DR   Q72S65, CHED1_LEPIC;  Q8F3H5, CHED1_LEPIN;  Q8TUQ4, CHED1_METAC;
DR   Q8Q012, CHED1_METMA;  Q221I2, CHED1_RHOFD;  Q8EF62, CHED1_SHEON;
DR   Q1GMD1, CHED1_SILST;  Q2LSK9, CHED1_SYNAS;  Q2IQR1, CHED2_ANADE;
DR   Q2T8Y7, CHED2_BURTA;  Q7NSI9, CHED2_CHRVO;  Q47GY0, CHED2_DECAR;
DR   Q39QQ2, CHED2_GEOMG;  Q74E20, CHED2_GEOSL;  Q75FT0, CHED2_LEPIC;
DR   Q8EXT3, CHED2_LEPIN;  Q8TLH2, CHED2_METAC;  Q8PXA0, CHED2_METMA;
DR   Q220A0, CHED2_RHOFD;  Q8EEQ1, CHED2_SHEON;  Q1GM98, CHED2_SILST;
DR   Q2LSL4, CHED2_SYNAS;  Q47GX8, CHED3_DECAR;  Q747R4, CHED3_GEOSL;
DR   A5G222, CHED_ACICJ ;  B9J950, CHED_AGRRK ;  Q7D1A4, CHED_AGRT5 ;
DR   O29224, CHED_ARCFU ;  A7Z4R7, CHED_BACA2 ;  Q9KA57, CHED_BACHD ;
DR   Q65JK2, CHED_BACLD ;  Q5WFS5, CHED_BACSK ;  P40404, CHED_BACSU ;
DR   Q6MJE9, CHED_BDEBA ;  Q2KUI9, CHED_BORA1 ;  Q0SMQ0, CHED_BORAP ;
DR   Q7WF29, CHED_BORBR ;  O51551, CHED_BORBU ;  B7J2G8, CHED_BORBZ ;
DR   Q660R6, CHED_BORGA ;  Q7W3Q2, CHED_BORPA ;  A9I174, CHED_BORPD ;
DR   Q7VST8, CHED_BORPE ;  A1R037, CHED_BORT9 ;  Q1BRL1, CHED_BURCA ;
DR   B1JTI2, CHED_BURCC ;  A3MQV3, CHED_BURM7 ;  A2S6U9, CHED_BURM9 ;
DR   Q62G11, CHED_BURMA ;  A1V905, CHED_BURMS ;  A3P0N1, CHED_BURP0 ;
DR   Q3JY64, CHED_BURP1 ;  Q63PS1, CHED_BURPS ;  Q39KQ2, CHED_BURS3 ;
DR   A4JAD2, CHED_BURVG ;  Q13SY1, CHED_BURXL ;  Q3ADC2, CHED_CARHZ ;
DR   B8GZ98, CHED_CAUCN ;  O87719, CHED_CAUCR ;  B0T4C1, CHED_CAUSK ;
DR   Q97GZ2, CHED_CLOAB ;  A7FX01, CHED_CLOB1 ;  C3L220, CHED_CLOB6 ;
DR   B2V1Y4, CHED_CLOBA ;  B2TLQ3, CHED_CLOBB ;  A5I5I5, CHED_CLOBH ;
DR   C1FUE9, CHED_CLOBJ ;  B1IKG3, CHED_CLOBK ;  A7GGW9, CHED_CLOBL ;
DR   B1KYG7, CHED_CLOBM ;  A5MZ48, CHED_CLOK5 ;  A0PZY2, CHED_CLONN ;
DR   A9KND1, CHED_CLOPH ;  Q893S5, CHED_CLOTE ;  Q46PH8, CHED_CUPPJ ;
DR   C6BSL0, CHED_DESAD ;  Q30WE0, CHED_DESDG ;  B8FTP6, CHED_DESHD ;
DR   Q24T84, CHED_DESHY ;  A4J742, CHED_DESRM ;  Q726Y4, CHED_DESVH ;
DR   Q5L0K6, CHED_GEOKA ;  B3E7P9, CHED_GEOLS ;  A4IMB9, CHED_GEOTN ;
DR   Q2SPQ2, CHED_HAHCH ;  A1WZ13, CHED_HALHL ;  Q5V0C3, CHED_HALMA ;
DR   A4G4P0, CHED_HERAR ;  A6SZT5, CHED_JANMA ;  Q28NF0, CHED_JANSC ;
DR   C1DCE3, CHED_LARHH ;  Q46DT9, CHED_METBF ;  Q1GZY9, CHED_METFK ;
DR   Q2FMT0, CHED_METHJ ;  A4FXW1, CHED_METM5 ;  A9AB16, CHED_METM6 ;
DR   A6VFL9, CHED_METM7 ;  Q6LYR0, CHED_METMP ;  A6UNQ9, CHED_METVS ;
DR   Q2RKC1, CHED_MOOTA ;  Q3IRU8, CHED_NATPD ;  Q0AGV5, CHED_NITEC ;
DR   Q82TM5, CHED_NITEU ;  Q8EQV8, CHED_OCEIH ;  Q3A5A7, CHED_PELCD ;
DR   Q3B327, CHED_PELLD ;  Q48ND8, CHED_PSE14 ;  C3K1P8, CHED_PSEFS ;
DR   Q888V7, CHED_PSESM ;  Q4ZYD2, CHED_PSEU2 ;  Q9UYF7, CHED_PYRAB ;
DR   O58226, CHED_PYRHO ;  Q5JF89, CHED_PYRKO ;  Q1LH12, CHED_RALME ;
DR   B2UHV5, CHED_RALPJ ;  Q8XQ82, CHED_RALSO ;  B3PPK3, CHED_RHIE6 ;
DR   Q2KCH6, CHED_RHIEC ;  Q1MLG6, CHED_RHIL3 ;  B5ZQC1, CHED_RHILW ;
DR   Q92S04, CHED_RHIME ;  C3MG06, CHED_RHISN ;  Q07SD5, CHED_RHOP5 ;
DR   Q2RUI7, CHED_RHORT ;  A3PIP7, CHED_RHOS1 ;  Q3J3N4, CHED_RHOS4 ;
DR   A4WTH0, CHED_RHOS5 ;  Q9JN41, CHED_RHOSH ;  Q21G19, CHED_SACD2 ;
DR   A6U619, CHED_SINMW ;  Q01VJ5, CHED_SOLUE ;  B4SHX1, CHED_STRM5 ;
DR   B2FQA1, CHED_STRMK ;  Q30RX6, CHED_SULDN ;  Q67P69, CHED_SYMTH ;
DR   Q0AYK9, CHED_SYNWW ;  Q9X005, CHED_THEMA ;  Q8RA16, CHED_THETN ;
DR   Q31F68, CHED_THICR ;  Q3SIF9, CHED_THIDA ;  A5F1A0, CHED_VIBC3 ;
DR   Q9KKL4, CHED_VIBCH ;  C3LX01, CHED_VIBCM ;  Q8D4X5, CHED_VIBVU ;
DR   Q7MBQ4, CHED_VIBVY ;  Q8PLB3, CHED_XANAC ;  Q3BUA1, CHED_XANC5 ;
DR   Q4UU98, CHED_XANC8 ;  B0RSS2, CHED_XANCB ;  Q8P9J6, CHED_XANCP ;
DR   Q2P1V9, CHED_XANOM ;  Q5GYV9, CHED_XANOR ;  Q5NRF0, CHED_ZYMMO ;
//
ID   3.5.1.45
DE   Transferred entry: 6.3.4.6.
//
ID   3.5.1.46
DE   6-aminohexanoate-dimer hydrolase.
AN   6-aminohexanoic acid oligomer hydrolase.
CA   N-(6-aminohexanoyl)-6-aminohexanoate + H(2)O = 2 6-aminohexanoate.
CC   -!- Also hydrolyzes, more slowly, oligomers of 6-aminohexanoate
CC       containing up to 6 residues.
CC   -!- The residues are removed sequentially from the N-terminus.
DR   P07061, NYLB_FLASK ;  P07062, NYLC_FLASK ;
//
ID   3.5.1.47
DE   N-acetyldiaminopimelate deacetylase.
CA   N-acetyl-LL-2,6-diaminoheptanedioate + H(2)O = acetate + LL-2,6-
CA   diaminoheptanedioate.
CC   -!- Formerly EC 3.1.1.62.
DR   B7GIC0, DAPEL_ANOFW;  A7Z433, DAPEL_BACA2;  C3P6Y7, DAPEL_BACAA;
DR   C3LI46, DAPEL_BACAC;  A0RHZ2, DAPEL_BACAH;  Q81MQ3, DAPEL_BACAN;
DR   B7JKV4, DAPEL_BACC0;  Q731Y6, DAPEL_BACC1;  B7IVL7, DAPEL_BACC2;
DR   C1EPZ4, DAPEL_BACC3;  B7H6W7, DAPEL_BACC4;  B7HMV1, DAPEL_BACC7;
DR   A7GS08, DAPEL_BACCN;  B9IW60, DAPEL_BACCQ;  Q819J6, DAPEL_BACCR;
DR   Q635U8, DAPEL_BACCZ;  Q9K9H9, DAPEL_BACHD;  Q6HEI5, DAPEL_BACHK;
DR   Q65K84, DAPEL_BACLD;  D5E0A1, DAPEL_BACMQ;  A8FCN2, DAPEL_BACP2;
DR   Q5WF94, DAPEL_BACSK;  O34916, DAPEL_BACSU;  A9VUE2, DAPEL_BACWK;
DR   C0ZGH7, DAPEL_BREBN;  Q836H7, DAPEL_ENTFA;  B1YJ90, DAPEL_EXIS2;
DR   Q5L145, DAPEL_GEOKA;  C5D827, DAPEL_GEOSW;  A4ILT6, DAPEL_GEOTN;
DR   Q5FKR0, DAPEL_LACAC;  Q03CW2, DAPEL_LACC3;  B3W7E6, DAPEL_LACCB;
DR   B2GC10, DAPEL_LACF3;  A8YUT2, DAPEL_LACH4;  Q9CIS4, DAPEL_LACLA;
DR   A2RI06, DAPEL_LACLM;  Q032G8, DAPEL_LACLS;  Q88V24, DAPEL_LACPL;
DR   A5VJ57, DAPEL_LACRD;  B2G6M8, DAPEL_LACRJ;  Q1WUQ7, DAPEL_LACS1;
DR   B1MZM9, DAPEL_LEUCK;  Q03YE3, DAPEL_LEUMM;  Q92D10, DAPEL_LISIN;
DR   Q6LAN3, DAPEL_LISIV;  C1L1T3, DAPEL_LISMC;  Q721F4, DAPEL_LISMF;
DR   B8DEC3, DAPEL_LISMH;  Q8Y8A0, DAPEL_LISMO;  A0AHD2, DAPEL_LISW6;
DR   Q8ERA3, DAPEL_OCEIH;  Q04FS2, DAPEL_OENOB;  Q03HT1, DAPEL_PEDPA;
DR   A8AUM0, DAPEL_STRGC;  Q8DVY6, DAPEL_STRMU;  Q04I78, DAPEL_STRP2;
DR   B5E3A3, DAPEL_STRP4;  C1CAS3, DAPEL_STRP7;  B1I9G2, DAPEL_STRPI;
DR   B8ZPL8, DAPEL_STRPJ;  Q97NE7, DAPEL_STRPN;  B2IN14, DAPEL_STRPS;
DR   Q8DN55, DAPEL_STRR6;  A4W4B4, DAPEL_STRS2;  A3CQT4, DAPEL_STRSV;
DR   A4VY21, DAPEL_STRSY;  Q5LXY3, DAPEL_STRT1;  Q5M2I5, DAPEL_STRT2;
DR   Q03IN1, DAPEL_STRTD;  B9DVY6, DAPEL_STRU0;  C1CH24, DAPEL_STRZJ;
DR   C1CN42, DAPEL_STRZP;  C1CTZ9, DAPEL_STRZT;
//
ID   3.5.1.48
DE   Acetylspermidine deacetylase.
AN   N(1)-acetylspermidine amidohydrolase.
AN   N(8)-acetylspermidine amidohydrolase.
AN   N(8)-acetylspermidine deacetylase.
AN   N(8)-monoacetylspermidine deacetylase.
AN   N-acetylspermidine deacetylase.
CA   N(8)-acetylspermidine + H(2)O = acetate + spermidine.
CC   -!- It was initially thought that N(1)-acetylspermidine was the substrate
CC       for this deacetylase reaction but this has since been disproved.
//
ID   3.5.1.49
DE   Formamidase.
AN   Formamide amidohydrolase.
CA   Formamide + H(2)O = formate + NH(3).
CC   -!- Also acts, more slowly, on acetamide, propanamide and butanamide.
DR   B9K1J4, AMIF_AGRVS ;  C3P6U6, AMIF_BACAA ;  C3LI05, AMIF_BACAC ;
DR   A0RHV8, AMIF_BACAH ;  P59700, AMIF_BACAN ;  B7JK27, AMIF_BACC0 ;
DR   B7IVH6, AMIF_BACC2 ;  C1EPV3, AMIF_BACC3 ;  B7H6S5, AMIF_BACC4 ;
DR   B9IW18, AMIF_BACCQ ;  P59701, AMIF_BACCR ;  Q635Y7, AMIF_BACCZ ;
DR   Q6HEM5, AMIF_BACHK ;  Q89H51, AMIF_BRAJA ;  A4Z3G9, AMIF_BRASO ;
DR   Q72CW9, AMIF_DESVH ;  A1VEP0, AMIF_DESVV ;  Q17WY3, AMIF_HELAH ;
DR   B6JN78, AMIF_HELP2 ;  B5Z8N3, AMIF_HELPG ;  Q1CS25, AMIF_HELPH ;
DR   Q9ZJY8, AMIF_HELPJ ;  B2UV01, AMIF_HELPS ;  O25836, AMIF_HELPY ;
DR   Q7N278, AMIF_PHOLL ;  Q887D9, AMIF_PSESM ;  Q4ZXA2, AMIF_PSEU2 ;
DR   Q50228, FMDA_METME ;  Q9URY7, FMDA_SCHPO ;
//
ID   3.5.1.50
DE   Pentanamidase.
AN   Valeramidase.
CA   Pentanamide + H(2)O = pentanoate + NH(3).
CC   -!- Also acts, more slowly, on other short-chain aliphatic amides.
CC   -!- Different from EC 3.5.1.49.
//
ID   3.5.1.51
DE   4-acetamidobutyryl-CoA deacetylase.
AN   Aminobutyryl-CoA thiolesterase.
CA   4-acetamidobutanoyl-CoA + H(2)O = acetate + 4-aminobutanoyl-CoA.
CC   -!- The enzyme also hydrolyzes 4-aminobutanoyl-CoA to aminobutanoate and
CC       coenzyme A.
CC   -!- Formerly EC 3.2.2.18.
//
ID   3.5.1.52
DE   Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase.
AN   Glycopeptidase.
AN   Glycopeptide N-glycosidase.
AN   N-glycanase.
AN   N-oligosaccharide glycopeptidase.
CA   Hydrolysis of an N(4)-(acetyl-beta-D-glucosaminyl)asparagine residue in
CA   which the glucosamine residue may be further glycosylated, to yield a
CA   (substituted) N-acetyl-beta-D-glucosaminylamine and a peptide containing
CA   an aspartate residue.
CC   -!- Does not act on (GlcNAc)-Asn, because it requires the presence of
CC       more than two amino-acid residues in the substrate (cf. EC 3.5.1.26).
CC   -!- Formerly EC 3.2.2.18.
DR   Q5WNE3, NGLY1_CAEBR;  Q9TW67, NGLY1_CAEEL;  Q5ZJM3, NGLY1_CHICK;
DR   Q503I8, NGLY1_DANRE;  Q7KRR5, NGLY1_DROME;  Q28YQ7, NGLY1_DROPS;
DR   Q96IV0, NGLY1_HUMAN;  Q4R6F3, NGLY1_MACFA;  Q9JI78, NGLY1_MOUSE;
DR   Q5XI55, NGLY1_RAT  ;  P81898, PNAA_PRUDU ;  Q9FGY9, PNG1_ARATH ;
DR   Q75D29, PNG1_ASHGO ;  Q59Q38, PNG1_CANAL ;  Q6FRU8, PNG1_CANGA ;
DR   Q6BNI6, PNG1_DEBHA ;  Q6CLZ6, PNG1_KLULA ;  Q7F0R1, PNG1_ORYSJ ;
DR   O74739, PNG1_SCHPO ;  Q6CAX5, PNG1_YARLI ;  Q02890, PNG1_YEAST ;
DR   P21163, PNGF_ELIMR ;
//
ID   3.5.1.53
DE   N-carbamoylputrescine amidase.
CA   N-carbamoylputrescine + H(2)O = putrescine + CO(2) + NH(3).
DR   Q8VYF5, AGUB_ARATH ;  Q93XI4, AGUB_ORYSJ ;  Q9XGI9, AGUB_SOLLC ;
DR   Q3HVN1, AGUB_SOLTU ;
//
ID   3.5.1.54
DE   Allophanate hydrolase.
CA   Urea-1-carboxylate + H(2)O = 2 CO(2) + 2 NH(3).
CC   -!- Along with EC 3.5.2.15 and EC 3.5.1.84, forms part of the cyanuric-
CC       acid metabolism pathway, which degrades s-triazide herbicides, such
CC       as atrazine (2-chloro-4-(ethylamino)-6-(isopropylamino)-1,3,5-
CC       triazine), in bacteria.
CC   -!- The Saccharomyces cerevisiae enzyme (but not that from green algae)
CC       also catalyzes the reaction of EC 6.3.4.6, thus bringing about the
CC       hydrolysis of urea to CO(2) and NH(3) in the presence of ATP and
CC       bicarbonate.
CC   -!- The enzyme from Pseudomonas sp. strain ADP has a narrow substrate
CC       specificity, being unable to use the structurally analogous compounds
CC       urea, hydroxyurea or methylcarbamate as substrate.
DR   A5H0J2, DUR1_SACKL ;  P32528, DUR1_YEAST ;
//
ID   3.5.1.55
DE   Long-chain-fatty-acyl-glutamate deacylase.
AN   Long-chain aminoacylase.
CA   N-long-chain-fatty-acyl-L-glutamate + H(2)O = a long-chain carboxylate +
CA   L-glutamate.
CC   -!- Does not act on acyl derivatives of other amino acids.
CC   -!- Optimum chain length of acyl residue is 12 to 16.
//
ID   3.5.1.56
DE   N,N-dimethylformamidase.
CA   N,N-dimethylformamide + H(2)O = dimethylamine + formate.
CF   Iron.
CC   -!- Also acts on N-ethylformamide and N-methylformamide and, more slowly,
CC       on N,N-diethylformamide, N,N-dimethylacetamide and unsubstituted acyl
CC       amides.
DR   Q9LCC1, DMFAA_ALCSP;  C9DQ22, DMFAA_PARAH;  Q9LCC0, DMFAB_ALCSP;
DR   C9DQ21, DMFAB_PARAH;
//
ID   3.5.1.57
DE   Tryptophanamidase.
CA   L-tryptophanamide + H(2)O = L-tryptophan + NH(3).
CF   Manganese.
CC   -!- Also acts on N-ethylformamide and L-tyrosinamide, and on some
CC       tryptophan dipeptides.
//
ID   3.5.1.58
DE   N-benzyloxycarbonylglycine hydrolase.
CA   N-benzyloxycarbonylglycine + H(2)O = benzyl alcohol + CO(2) + glycine.
CF   Cobalt; Zinc.
CC   -!- Also acts, more slowly, on N-benzyloxycarbonylalanine, but not on the
CC       corresponding derivatives of other amino acids or on
CC       N-benzyloxycarbonylpeptides (cf. EC 3.5.1.64).
//
ID   3.5.1.59
DE   N-carbamoylsarcosine amidase.
AN   CSHase.
AN   N-carbamoylsarcosine amidohydrolase.
CA   N-carbamoylsarcosine + H(2)O = sarcosine + CO(2) + NH(3).
DR   P32400, CSH_ARTSP  ;
//
ID   3.5.1.60
DE   N-(long-chain-acyl)ethanolamine deacylase.
AN   N-acylethanolamine amidohydrolase.
CA   N-(long-chain-acyl)ethanolamine + H(2)O = a long-chain carboxylate +
CA   ethanolamine.
CC   -!- Does not act on N-acylsphingosine or N,O-diacylethanolamine.
//
ID   3.5.1.61
DE   Mimosinase.
AN   Mimosine amidohydrolase.
CA   (S)-2-amino-3-(3-hydroxy-4-oxo-4H-pyridin-1-yl)propanoate + H(2)O =
CA   3-hydroxy-4H-pyrid-4-one + L-serine.
CC   -!- An enzyme from Leucaena leucocephala leaf, which also contains the
CC       toxic amino acid, mimosine.
//
ID   3.5.1.62
DE   Acetylputrescine deacetylase.
CA   N-acetylputrescine + H(2)O = acetate + putrescine.
CC   -!- The enzyme from Micrococcus luteus also acts on N(8)-acetylspermidine
CC       and acetylcadaverine, but more slowly.
//
ID   3.5.1.63
DE   4-acetamidobutyrate deacetylase.
CA   4-acetamidobutanoate + H(2)O = acetate + 4-aminobutanoate.
CC   -!- Also acts on N-acetyl-beta-alanine and 5-acetamidopentanoate.
//
ID   3.5.1.64
DE   N(alpha)-benzyloxycarbonylleucine hydrolase.
CA   N(alpha)-benzyloxycarbonyl-L-leucine + H(2)O = benzyl alcohol + CO(2) +
CA   L-leucine.
CC   -!- Also acts on N(alpha)-t-butoxycarbonyl-L-leucine, and, more slowly,
CC       on the corresponding derivatives of L-aspartate, L-methionine,
CC       L-glutamate and L-alanine (cf. EC 3.5.1.58).
//
ID   3.5.1.65
DE   Theanine hydrolase.
CA   N(5)-ethyl-L-glutamine + H(2)O = L-glutamate + ethylamine.
CC   -!- Also acts on other N-alkyl-L-glutamines.
//
ID   3.5.1.66
DE   2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase.
CA   2-(hydroxymethyl)-3-(acetamidomethylene)succinate + 2 H(2)O = acetate +
CA   2-(hydroxymethyl)-4-oxobutanoate + NH(3) + CO(2).
CC   -!- Involved in the degradation of pyridoxin by Pseudomonas and
CC       Arthrobacter.
//
ID   3.5.1.67
DE   4-methyleneglutaminase.
AN   4-methyleneglutamine deamidase.
CA   4-methylene-L-glutamine + H(2)O = 4-methylene-L-glutamate + NH(3).
//
ID   3.5.1.68
DE   N-formylglutamate deformylase.
AN   Beta-citryl-L-glutamate hydrolase.
CA   N-formyl-L-glutamate + H(2)O = formate + L-glutamate.
CC   -!- The animal enzyme also acts on beta-citryl-L-glutamate and beta-
CC       citryl-L-glutamine.
//
ID   3.5.1.69
DE   Glycosphingolipid deacylase.
AN   Glycosphingolipid ceramide deacylase.
CA   Hydrolysis of gangliosides and neutral glycosphingolipids, releasing
CA   fatty acids to form the lyso-derivatives.
CC   -!- Does not act on sphingolipids such as ceramide.
CC   -!- Not identical with EC 3.5.1.23.
//
ID   3.5.1.70
DE   Aculeacin-A deacylase.
CA   Hydrolysis of the amide bond in aculeacin A and related neutral
CA   lipopeptide antibiotics, releasing the long-chain fatty acid side-chain.
//
ID   3.5.1.71
DE   N-feruloylglycine deacylase.
CA   N-feruloylglycine + H(2)O = ferulate + glycine.
CC   -!- Hydrolyzes a range of L-amino acids from the cinnamoyl and
CC       substituted cinnamoyl series.
CC   -!- Not identical with EC 3.5.1.14.
//
ID   3.5.1.72
DE   D-benzoylarginine-4-nitroanilide amidase.
CA   N-benzoyl-D-arginine-4-nitroanilide + H(2)O = N-benzoyl-D-arginine +
CA   4-nitroaniline.
//
ID   3.5.1.73
DE   Carnitinamidase.
CA   L-carnitinamide + H(2)O = L-carnitine + NH(3).
CC   -!- Does not act on D-carnitinamide.
//
ID   3.5.1.74
DE   Chenodeoxycholoyltaurine hydrolase.
CA   Chenodeoxycholoyltaurine + H(2)O = chenodeoxycholate + taurine.
CC   -!- Some other taurine conjugates are hydrolyzed, but not glycine
CC       conjugates of bile acids.
//
ID   3.5.1.75
DE   Urethanase.
AN   Urethane hydrolase.
CA   Urethane + H(2)O = ethanol + CO(2) + NH(3).
//
ID   3.5.1.76
DE   Arylalkyl acylamidase.
AN   Aralkyl acylamidase.
CA   N-acetylarylalkylamine + H(2)O = arylalkylamine + acetate.
CC   -!- Strict specificity for N-acetyl arylalkylamines, including N-acetyl-
CC       2-phenylethylamine, N-acetyl-3-phenylpropylamine, N-acetyldopamine,
CC       N-acetyl-serotonin and melatonin.
CC   -!- It also accepts arylalkyl acetates but not acetanilide derivatives,
CC       which are common substrates of EC 3.5.1.13.
DR   P35902, ARYA_PSEPU ;
//
ID   3.5.1.77
DE   N-carbamoyl-D-amino-acid hydrolase.
AN   D-N-carbamoylase.
AN   N-carbamoyl-D-amino acid hydrolase.
AN   N-carbamoylase.
CA   N-carbamoyl-D-amino acid + H(2)O = D-amino acid + NH(3) + CO(2).
CC   -!- This enzyme, along with EC 3.5.1.87, EC 5.1.99.5 and EC 3.5.2.2,
CC       forms part of the reaction cascade known as the 'hydantoinase
CC       process', which allows the total conversion of D,L-5-monosubstituted
CC       hydantoins into optically pure D- or L-amino acids.
CC   -!- Has strict stereospecificity for N-carbamoyl-D-amino acids and does
CC       not act upon the corresponding L-amino acids or N-formyl amino acids,
CC       N-carbamoyl-sarcosine, -citrulline, -allantoin and -ureidopropanoate,
CC       which are substrates for other amidohydrolases.
DR   P60327, DCAS_AGRSK ;  Q44185, DCAS_RHIRD ;
//
ID   3.5.1.78
DE   Glutathionylspermidine amidase.
AN   Glutathionylspermidine amidohydrolase (spermidine-forming).
AN   GSP amidase.
CA   N(1)-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + H(2)O = gamma-L-
CA   glutamyl-L-cysteinyl-glycine + spermidine.
CC   -!- Transforms glutathionylspermidine into glutathione and spermidine.
CC   -!- The enzyme from Escherichia coli is bifunctional and also catalyzes
CC       the reaction of EC 6.3.1.8, resulting in a net hydrolysis of ATP.
DR   P0AES0, GSP_ECOLI  ;  P0AES1, GSP_SHIFL  ;
//
ID   3.5.1.79
DE   Phthalyl amidase.
AN   o-phthalyl amidase.
CA   A phthalylamide + H(2)O = phthalic acid + a substituted amine.
CC   -!- Phthalyl is used to mean 2-carboxybenzoyl.
CC   -!- The enzyme from Xanthobacter agilis hydrolyzes phthalylated amino
CC       acids, peptides, beta-lactams, aromatic and aliphatic amines.
CC   -!- The substituent on nitrogen may be an alkyl group, but may also be
CC       complex, giving an amino acid or peptide derivative.
CC   -!- Substitutions on the phthalyl ring include 6-F, 6-NH(2), 3-OH, and a
CC       nitrogen in the aromatic ring ortho to the carboxy group attached to
CC       the amine.
DR   P0C2Y0, PHAM_XANAG ;
//
ID   3.5.1.80
DE   Transferred entry: 3.5.1.25.
//
ID   3.5.1.81
DE   N-acyl-D-amino-acid deacylase.
AN   D-aminoacylase.
CA   N-acyl-D-amino acid + H(2)O = an acid + D-amino acid.
CF   Zinc.
CC   -!- Has a wide specificity; hydrolyzes N-acyl derivative of neutral
CC       D-amino acids.
CC   -!- Used in separating D- and L-amino acids.
DR   P72349, NDAD_ALCXX ;
//
ID   3.5.1.82
DE   N-acyl-D-glutamate deacylase.
AN   N-acyl-D-glutamate amidohydrolase.
CA   N-acyl-D-glutamate + H(2)O = a carboxylate + D-glutamate.
CF   Zinc.
DR   P94211, NDED_ALCXX ;
//
ID   3.5.1.83
DE   N-acyl-D-aspartate deacylase.
AN   N-acyl-D-aspartate amidohydrolase.
CA   N-acyl-D-aspartate + H(2)O = a carboxylate + D-aspartate.
CF   Zinc.
DR   P94212, NDDD_ALCXX ;
//
ID   3.5.1.84
DE   Biuret amidohydrolase.
CA   Biuret + H(2)O = urea-1-carboxylate + NH(3).
CC   -!- Along with EC 3.5.2.15 and EC 3.5.1.54, this enzyme forms part of the
CC       cyanuric-acid metabolism pathway, which degrades s-triazide
CC       herbicides, such as atrazine (2-chloro-4-(ethylamino)-6-
CC       (isopropylamino)-1,3,5-triazine), in bacteria.
CC   -!- Urea-1-carboxylate rather than urea (as was thought previously) is
CC       the 2-nitrogen intermediate in cyanuric-acid metabolism in bacteria.
CC   -!- The product, urea-1-carboxylate, can spontaneously decarboxylate
CC       under acidic conditions to form urea but, under physiological
CC       conditions, it can be converted into CO(2) and ammonia by the action
CC       of EC 3.5.1.54.
//
ID   3.5.1.85
DE   (S)-N-acetyl-1-phenylethylamine hydrolase.
AN   (S)-N-acetyl-1-phenylethylamine amidohydrolase.
CA   N-acetylphenylethylamine + H(2)O = phenylethylamine + acetate.
CC   -!- Inhibited by phenylmethanesulfonyl fluoride.
CC   -!- Some related acetylated compounds are hydrolyzed with variable
CC       enantiomeric selectivities.
//
ID   3.5.1.86
DE   Mandelamide amidase.
AN   Mandelamide hydrolase.
CA   (R)-mandelamide + H(2)O = (R)-mandelate + NH(3).
DR   Q84DC4, MANHY_PSEPU;
//
ID   3.5.1.87
DE   N-carbamoyl-L-amino-acid hydrolase.
AN   L-carbamoylase.
AN   L-N-carbamoylase.
AN   N-carbamoyl-L-amino acid amidohydrolase.
AN   N-carbamoylase.
AN   N-carbamyl L-amino acid amidohydrolase.
CA   N-carbamoyl-L-2-amino acid (a 2-ureido carboxylate) + H(2)O = L-2-amino
CA   acid + NH(3) + CO(2).
CF   Cobalt or nickel or manganese.
CC   -!- This enzyme, along with EC 3.5.1.77, EC 5.1.99.5 and EC 3.5.2.2,
CC       forms part of the reaction cascade known as the 'hydantoinase
CC       process', which allows the total conversion of D,L-5-monosubstituted
CC       hydantoins into optically pure D- or L-amino acids.
CC   -!- The enzyme from Alcaligenes xylosoxidans has broad specificity for
CC       carbamoyl-L-amino acids, although it is inactive on the carbamoyl
CC       derivatives of glutamate, aspartate, arginine, tyrosine or
CC       tryptophan.
CC   -!- The enzyme from Sinorhizobium meliloti requires a divalent cation for
CC       activity and can hydrolyze N-carbamoyl-L-tryptophan as well as
CC       N-carbamoyl L-amino acids with aliphatic substituents.
CC   -!- The enzyme is inactive on derivatives of D-amino acids.
CC   -!- In addition to N-carbamoyl L-amino acids, the enzyme can also
CC       hydrolyze formyl and acetyl derivatives to varying degrees.
DR   P37113, AMAB1_GEOSE;  Q53389, AMAB2_GEOSE;
//
ID   3.5.1.88
DE   Peptide deformylase.
AN   PDF.
AN   Polypeptide deformylase.
CA   Formyl-L-methionyl peptide + H(2)O = formate + methionyl peptide.
CF   Fe(2+).
CC   -!- Requires at least a dipeptide for an efficient rate of reaction.
CC   -!- N-terminal L-methionine is a prerequisite for activity but the enzyme
CC       has broad specificity at other positions.
CC   -!- Differs in substrate specificity from EC 3.5.1.27 and EC 3.5.1.31.
DR   Q9FV53, DEF1A_ARATH;  B6RGY0, DEF1A_ORYSJ;  Q9FUZ0, DEF1A_SOLLC;
DR   Q9FUZ2, DEF1B_ARATH;  Q5VNN5, DEF1B_ORYSJ;  Q9FV54, DEF1B_SOLLC;
DR   Q81WH1, DEF1_BACAN ;  Q819U0, DEF1_BACCR ;  P94462, DEF1_BACSU ;
DR   Q8G534, DEF1_BIFLO ;  Q7WQS9, DEF1_BORBR ;  Q7W1V3, DEF1_BORPA ;
DR   Q7W0Q0, DEF1_BORPE ;  O05100, DEF1_CLOAB ;  Q8XJL2, DEF1_CLOPE ;
DR   Q8FT51, DEF1_COREF ;  Q8NQ46, DEF1_CORGL ;  Q83CV9, DEF1_COXBU ;
DR   Q7NJV3, DEF1_GLOVI ;  Q82TW4, DEF1_NITEU ;  Q8YSK6, DEF1_NOSS1 ;
DR   Q7V8G6, DEF1_PROMM ;  Q88RR1, DEF1_PSEPK ;  Q88B43, DEF1_PSESM ;
DR   Q8Y3B0, DEF1_RALSO ;  Q92IZ1, DEF1_RICCN ;  Q8EKQ8, DEF1_SHEON ;
DR   Q82IV0, DEF1_STRAW ;  Q9RD27, DEF1_STRCO ;  Q9KVU3, DEF1_VIBCH ;
DR   Q87KD5, DEF1_VIBPA ;  Q8DDE3, DEF1_VIBVU ;  Q7MCQ2, DEF1_VIBVY ;
DR   Q8PGV2, DEF1_XANAC ;  Q8PCN7, DEF1_XANCP ;  Q81MQ9, DEF2_BACAN ;
DR   Q819K2, DEF2_BACCR ;  Q45495, DEF2_BACSU ;  Q8G487, DEF2_BIFLO ;
DR   Q7WG25, DEF2_BORBR ;  Q7W4K0, DEF2_BORPA ;  Q7VS88, DEF2_BORPE ;
DR   Q97G95, DEF2_CLOAB ;  Q8XJX0, DEF2_CLOPE ;  Q8FMD0, DEF2_COREF ;
DR   Q8NM41, DEF2_CORGL ;  Q83AK6, DEF2_COXBU ;  O31410, DEF2_GEOSE ;
DR   Q7NIF5, DEF2_GLOVI ;  Q82TC8, DEF2_NITEU ;  Q8YVH1, DEF2_NOSS1 ;
DR   Q7V5F9, DEF2_PROMM ;  Q88EA7, DEF2_PSEPK ;  Q886I1, DEF2_PSESM ;
DR   Q8XZJ6, DEF2_RALSO ;  Q92JI7, DEF2_RICCN ;  Q8EHZ2, DEF2_SHEON ;
DR   Q826Q0, DEF2_STRAW ;  Q9FCA2, DEF2_STRCO ;  Q9KN16, DEF2_VIBCH ;
DR   Q87I22, DEF2_VIBPA ;  Q8D5P5, DEF2_VIBVU ;  Q7MGK6, DEF2_VIBVY ;
DR   Q8PG20, DEF2_XANAC ;  Q8P4F9, DEF2_XANCP ;  Q8EE60, DEF3_SHEON ;
DR   Q825U9, DEF3_STRAW ;  Q9XAQ2, DEF3_STRCO ;  Q9K4A0, DEF4_STRCO ;
DR   Q9HBH1, DEFM_HUMAN ;  B0VNL8, DEF_ACIBS  ;  A0LUE1, DEF_ACIC1  ;
DR   C1F541, DEF_ACIC5  ;  B3GYT7, DEF_ACTP7  ;  A4ST57, DEF_AERS4  ;
DR   Q8UID1, DEF_AGRT5  ;  Q0VTE1, DEF_ALCBS  ;  Q0A5B9, DEF_ALHEH  ;
DR   B6EP21, DEF_ALISL  ;  A6TRW8, DEF_ALKMQ  ;  B4S291, DEF_ALTMD  ;
DR   B3ETT4, DEF_AMOA5  ;  B9MR36, DEF_ANATD  ;  O66847, DEF_AQUAE  ;
DR   C1DFV8, DEF_AZOVD  ;  Q5LEQ9, DEF_BACFN  ;  Q64VP5, DEF_BACFR  ;
DR   Q9K9I9, DEF_BACHD  ;  Q5WFA2, DEF_BACSK  ;  Q8AAP4, DEF_BACTN  ;
DR   A6L7J9, DEF_BACV8  ;  A1UUB4, DEF_BARBK  ;  Q6G5F0, DEF_BARHE  ;
DR   Q6G1G6, DEF_BARQU  ;  A9ILK4, DEF_BART1  ;  Q1LT56, DEF_BAUCH  ;
DR   A1A2Z1, DEF_BIFAA  ;  Q7VQC0, DEF_BLOFL  ;  Q493I1, DEF_BLOPB  ;
DR   O51092, DEF_BORBU  ;  C0QZQ2, DEF_BRAHW  ;  Q89BN9, DEF_BRAJA  ;
DR   A5ESQ7, DEF_BRASB  ;  A4YLB9, DEF_BRASO  ;  P63913, DEF_BRUME  ;
DR   P63914, DEF_BRUSU  ;  B8D9R9, DEF_BUCA5  ;  P57563, DEF_BUCAI  ;
DR   Q8K975, DEF_BUCAP  ;  B8D821, DEF_BUCAT  ;  P59493, DEF_BUCBP  ;
DR   Q057D2, DEF_BUCCC  ;  Q9PIT8, DEF_CAMJE  ;  Q3AC18, DEF_CARHZ  ;
DR   B8GYE3, DEF_CAUCN  ;  Q9ABF5, DEF_CAUCR  ;  B0T1S9, DEF_CAUSK  ;
DR   B3PGY7, DEF_CELJU  ;  A9WHG7, DEF_CHLAA  ;  Q5L6G8, DEF_CHLAB  ;
DR   B8G5R5, DEF_CHLAD  ;  Q823U4, DEF_CHLCV  ;  Q253S4, DEF_CHLFF  ;
DR   B3EE19, DEF_CHLL2  ;  Q9PK41, DEF_CHLMU  ;  B3QPU5, DEF_CHLP8  ;
DR   B3EPG5, DEF_CHLPB  ;  A1BHK0, DEF_CHLPD  ;  Q9Z6J2, DEF_CHLPN  ;
DR   B9LBS4, DEF_CHLSY  ;  B0B7S2, DEF_CHLT2  ;  Q3KM05, DEF_CHLTA  ;
DR   B0BBY7, DEF_CHLTB  ;  Q8KCG7, DEF_CHLTE  ;  O84357, DEF_CHLTR  ;
DR   Q1QTJ5, DEF_CHRSD  ;  Q7NQ75, DEF_CHRVO  ;  A8AQI1, DEF_CITK8  ;
DR   O08450, DEF_CLOB8  ;  B2V4B1, DEF_CLOBA  ;  A9KM99, DEF_CLOPH  ;
DR   Q895Q2, DEF_CLOTE  ;  A3DCX4, DEF_CLOTH  ;  Q11X86, DEF_CYTH3  ;
DR   Q3Z8F6, DEF_DEHE1  ;  A5FRA7, DEF_DEHSB  ;  Q3ZXA9, DEF_DEHSC  ;
DR   Q9RRQ4, DEF_DEIRA  ;  B8FHH0, DEF_DESAA  ;  C0QI55, DEF_DESAH  ;
DR   B1I504, DEF_DESAP  ;  B8FS81, DEF_DESHD  ;  Q24U09, DEF_DESHY  ;
DR   A8ZUK5, DEF_DESOH  ;  Q6AQ98, DEF_DESPS  ;  A5EWL8, DEF_DICNV  ;
DR   B5YF46, DEF_DICT6  ;  B8E0X7, DEF_DICTD  ;  B7UK10, DEF_ECO27  ;
DR   B7MCQ2, DEF_ECO45  ;  B7LHY3, DEF_ECO55  ;  P0A6K5, DEF_ECO57  ;
DR   B5YT06, DEF_ECO5E  ;  B7NLK6, DEF_ECO7I  ;  B7N171, DEF_ECO81  ;
DR   B7M0Z2, DEF_ECO8A  ;  C4ZUE1, DEF_ECOBW  ;  B1X6D9, DEF_ECODH  ;
DR   A8A591, DEF_ECOHS  ;  A1AGH8, DEF_ECOK1  ;  Q0TCH5, DEF_ECOL5  ;
DR   P0A6K4, DEF_ECOL6  ;  B1IQ13, DEF_ECOLC  ;  P0A6K3, DEF_ECOLI  ;
DR   B7NDQ8, DEF_ECOLU  ;  B6I200, DEF_ECOSE  ;  B1LGP3, DEF_ECOSM  ;
DR   Q1R646, DEF_ECOUT  ;  C5BF17, DEF_EDWI9  ;  B2KD65, DEF_ELUMP  ;
DR   A4WF95, DEF_ENT38  ;  Q82ZJ0, DEF_ENTFA  ;  A7MPE9, DEF_ENTS8  ;
DR   Q6D002, DEF_ERWCT  ;  B2VK93, DEF_ERWT9  ;  Q2NCT3, DEF_ERYLH  ;
DR   B7LRQ3, DEF_ESCF3  ;  C4ZEV9, DEF_EUBR3  ;  B0S139, DEF_FINM2  ;
DR   A5FGV5, DEF_FLAJ1  ;  A6H0E7, DEF_FLAPJ  ;  A8LE21, DEF_FRASN  ;
DR   P94601, DEF_FREDI  ;  Q8REF0, DEF_FUSNN  ;  A0M3P3, DEF_GRAFK  ;
DR   Q7VKK9, DEF_HAEDU  ;  Q4QMV6, DEF_HAEI8  ;  A5UEB4, DEF_HAEIE  ;
DR   A5UH92, DEF_HAEIG  ;  P44786, DEF_HAEIN  ;  B8F726, DEF_HAEPS  ;
DR   Q0I181, DEF_HAES1  ;  B0UWZ5, DEF_HAES2  ;  Q2SQX1, DEF_HAHCH  ;
DR   B8CWS6, DEF_HALOH  ;  C4K6Y0, DEF_HAMD5  ;  Q17XD4, DEF_HELAH  ;
DR   Q7VIN5, DEF_HELHP  ;  B0TGS8, DEF_HELMI  ;  B6JM24, DEF_HELP2  ;
DR   B5Z7F5, DEF_HELPG  ;  Q1CT77, DEF_HELPH  ;  Q9ZL51, DEF_HELPJ  ;
DR   B2UT38, DEF_HELPS  ;  P56419, DEF_HELPY  ;  Q0C4V1, DEF_HYPNA  ;
DR   Q5QXI5, DEF_IDILO  ;  B5XNC4, DEF_KLEP3  ;  A6TEU0, DEF_KLEP7  ;
DR   Q03QL3, DEF_LACBA  ;  Q039N7, DEF_LACC3  ;  B3WE13, DEF_LACCB  ;
DR   Q1GAR4, DEF_LACDA  ;  Q04B51, DEF_LACDB  ;  B2GBA3, DEF_LACF3  ;
DR   Q042S1, DEF_LACGA  ;  A8YUR0, DEF_LACH4  ;  Q74JW2, DEF_LACJO  ;
DR   Q48661, DEF_LACLA  ;  Q88VB2, DEF_LACPL  ;  A5VJ71, DEF_LACRD  ;
DR   B2G6P1, DEF_LACRJ  ;  Q1WU76, DEF_LACS1  ;  Q38WP3, DEF_LACSS  ;
DR   B0SHH1, DEF_LEPBA  ;  Q04RW4, DEF_LEPBJ  ;  Q051Q7, DEF_LEPBL  ;
DR   B0SQM2, DEF_LEPBP  ;  Q72S74, DEF_LEPIC  ;  Q93LE9, DEF_LEPIN  ;
DR   Q92CX8, DEF_LISIN  ;  C1L1X2, DEF_LISMC  ;  Q721B5, DEF_LISMF  ;
DR   B8DCF7, DEF_LISMH  ;  Q8Y866, DEF_LISMO  ;  A0AHG3, DEF_LISW6  ;
DR   B9EB04, DEF_MACCJ  ;  Q65QF2, DEF_MANSM  ;  Q0ASK2, DEF_MARMM  ;
DR   Q11LC7, DEF_MESSB  ;  B3DUG9, DEF_METI4  ;  B8ENG6, DEF_METSB  ;
DR   Q2RK25, DEF_MOOTA  ;  B1MIN9, DEF_MYCA9  ;  Q7U206, DEF_MYCBO  ;
DR   A1KFQ1, DEF_MYCBP  ;  C1AKA5, DEF_MYCBT  ;  Q7NAK8, DEF_MYCGA  ;
DR   P47352, DEF_MYCGE  ;  A4T2T4, DEF_MYCGI  ;  B8ZSF6, DEF_MYCLB  ;
DR   Q9CBI2, DEF_MYCLE  ;  B2HQN4, DEF_MYCMM  ;  Q73T03, DEF_MYCPA  ;
DR   Q8EVJ8, DEF_MYCPE  ;  P75527, DEF_MYCPN  ;  Q98PN3, DEF_MYCPU  ;
DR   A0QQP8, DEF_MYCS2  ;  A3PTZ4, DEF_MYCSJ  ;  A1UAD9, DEF_MYCSK  ;
DR   Q1BEJ4, DEF_MYCSS  ;  A5TZF5, DEF_MYCTA  ;  P96275, DEF_MYCTU  ;
DR   A0PNK2, DEF_MYCUA  ;  A1T320, DEF_MYCVP  ;  B2A2K1, DEF_NATTJ  ;
DR   B9L6X1, DEF_NAUPA  ;  Q5F5P6, DEF_NEIG1  ;  A9M464, DEF_NEIM0  ;
DR   P63915, DEF_NEIMA  ;  P63916, DEF_NEIMB  ;  A1KRE5, DEF_NEIMF  ;
DR   Q2GE16, DEF_NEOSM  ;  Q1QH78, DEF_NITHX  ;  Q3J6U0, DEF_NITOC  ;
DR   Q2G491, DEF_NOVAD  ;  Q8ER96, DEF_OCEIH  ;  B6JJP8, DEF_OLICO  ;
DR   B1ZMD5, DEF_OPITP  ;  A5CF65, DEF_ORITB  ;  B3CTU1, DEF_ORITI  ;
DR   A6L9R8, DEF_PARD8  ;  P57948, DEF_PASMU  ;  C6DFR5, DEF_PECCP  ;
DR   Q03F09, DEF_PEDPA  ;  Q3B2U9, DEF_PELLD  ;  B4SBG6, DEF_PELPB  ;
DR   A5D1C0, DEF_PELTS  ;  Q4FNG1, DEF_PELUB  ;  B4RDT8, DEF_PHEZH  ;
DR   Q7MYI2, DEF_PHOLL  ;  B1XSN2, DEF_POLNS  ;  B2RMJ1, DEF_PORG3  ;
DR   Q7MT07, DEF_PORGI  ;  B4S9B9, DEF_PROA2  ;  A2BZN6, DEF_PROM1  ;
DR   A2BU25, DEF_PROM5  ;  Q31DB4, DEF_PROM9  ;  Q7VED2, DEF_PROMA  ;
DR   Q7V3K7, DEF_PROMP  ;  A2BNK7, DEF_PROMS  ;  Q46HV9, DEF_PROMT  ;
DR   A4SFP2, DEF_PROVI  ;  Q9I7A8, DEF_PSEAE  ;  Q3IDI2, DEF_PSEHT  ;
DR   A4XNB3, DEF_PSEMY  ;  A4VFH8, DEF_PSEU5  ;  Q4FVQ4, DEF_PSYA2  ;
DR   Q1QET1, DEF_PSYCK  ;  A5WBG1, DEF_PSYWF  ;  Q98D52, DEF_RHILO  ;
DR   Q92SH6, DEF_RHIME  ;  Q7UHZ5, DEF_RHOBA  ;  C1B0D9, DEF_RHOOB  ;
DR   Q2J2C6, DEF_RHOP2  ;  Q07TX0, DEF_RHOP5  ;  Q6NC51, DEF_RHOPA  ;
DR   Q21B62, DEF_RHOPB  ;  Q13F18, DEF_RHOPS  ;  B3QCH1, DEF_RHOPT  ;
DR   A8GMJ8, DEF_RICAH  ;  A8EXV2, DEF_RICCK  ;  Q9ZDV8, DEF_RICPR  ;
DR   Q68XG1, DEF_RICTY  ;  A7NPM9, DEF_ROSCS  ;  A5US58, DEF_ROSS1  ;
DR   Q21PV5, DEF_SACD2  ;  B5F7R3, DEF_SALA4  ;  A9MN80, DEF_SALAR  ;
DR   Q57J64, DEF_SALCH  ;  B5FJI2, DEF_SALDC  ;  B5R1E3, DEF_SALEP  ;
DR   B5RH49, DEF_SALG2  ;  B4TJX7, DEF_SALHS  ;  B4SUQ8, DEF_SALNS  ;
DR   Q5PIT8, DEF_SALPA  ;  A9N8B1, DEF_SALPB  ;  B5BGV3, DEF_SALPK  ;
DR   Q2S316, DEF_SALRD  ;  B4TXB0, DEF_SALSV  ;  Q8Z1W9, DEF_SALTI  ;
DR   Q8ZLM7, DEF_SALTY  ;  A8GKG5, DEF_SERP5  ;  B2U2Q4, DEF_SHIB3  ;
DR   Q31VZ0, DEF_SHIBS  ;  Q32B63, DEF_SHIDS  ;  Q0T016, DEF_SHIF8  ;
DR   Q83PZ1, DEF_SHIFL  ;  Q3YWX3, DEF_SHISS  ;  Q2NQQ4, DEF_SODGM  ;
DR   A5VDM3, DEF_SPHWW  ;  Q5HGZ3, DEF_STAAC  ;  P68825, DEF_STAAM  ;
DR   P99077, DEF_STAAN  ;  Q6GHZ4, DEF_STAAR  ;  Q6GAC3, DEF_STAAS  ;
DR   P68826, DEF_STAAU  ;  Q8NX78, DEF_STAAW  ;  Q5HQ78, DEF_STAEQ  ;
DR   Q8CPN4, DEF_STAES  ;  Q3JZ45, DEF_STRA1  ;  Q8E378, DEF_STRA3  ;
DR   Q8DXF6, DEF_STRA5  ;  C0M9E1, DEF_STRE4  ;  B4U576, DEF_STREM  ;
DR   A8AV30, DEF_STRGC  ;  B4SKH7, DEF_STRM5  ;  B2FIR4, DEF_STRMK  ;
DR   Q8DWC2, DEF_STRMU  ;  P68771, DEF_STRP1  ;  Q04JP7, DEF_STRP2  ;
DR   P0DC96, DEF_STRP3  ;  B5E5U9, DEF_STRP4  ;  Q5X9V1, DEF_STRP6  ;
DR   C1C851, DEF_STRP7  ;  Q8NZB7, DEF_STRP8  ;  Q1J9R7, DEF_STRPB  ;
DR   Q1JJW6, DEF_STRPC  ;  Q1JEV7, DEF_STRPD  ;  Q1J4M3, DEF_STRPF  ;
DR   A2RGI0, DEF_STRPG  ;  B1ICN7, DEF_STRPI  ;  B8ZL02, DEF_STRPJ  ;
DR   Q48R93, DEF_STRPM  ;  Q9F2F0, DEF_STRPN  ;  P0DC97, DEF_STRPQ  ;
DR   B2IQS1, DEF_STRPS  ;  B5XIL1, DEF_STRPZ  ;  Q8DP79, DEF_STRR6  ;
DR   A4W418, DEF_STRS2  ;  C0MFA6, DEF_STRS7  ;  A4VXS1, DEF_STRSY  ;
DR   Q5M1R9, DEF_STRT1  ;  Q5M6B0, DEF_STRT2  ;  Q03MP6, DEF_STRTD  ;
DR   B9DTD6, DEF_STRU0  ;  C1CF38, DEF_STRZJ  ;  C1CLF5, DEF_STRZP  ;
DR   C1CQR2, DEF_STRZT  ;  A8Z5V9, DEF_SULMW  ;  Q67PR5, DEF_SYMTH  ;
DR   A0LEJ7, DEF_SYNFM  ;  B1XJP0, DEF_SYNP2  ;  Q7U9D4, DEF_SYNPX  ;
DR   A5GQU9, DEF_SYNR3  ;  Q0I7A5, DEF_SYNS3  ;  Q3AZU8, DEF_SYNS9  ;
DR   Q3AHC4, DEF_SYNSC  ;  Q0AXL3, DEF_SYNWW  ;  P73441, DEF_SYNY3  ;
DR   C5BKQ0, DEF_TERTT  ;  Q8DIB4, DEF_THEEB  ;  A8F524, DEF_THELT  ;
DR   P96113, DEF_THEMA  ;  B9K7G9, DEF_THENN  ;  A5ILS1, DEF_THEP1  ;
DR   B0KA11, DEF_THEP3  ;  B0K292, DEF_THEPX  ;  B9L0C1, DEF_THERP  ;
DR   B1LB14, DEF_THESQ  ;  Q72H33, DEF_THET2  ;  Q5SLH2, DEF_THET8  ;
DR   P43522, DEF_THETH  ;  Q8R9T0, DEF_THETN  ;  B5YIL7, DEF_THEYD  ;
DR   Q31J84, DEF_THICR  ;  B8GU11, DEF_THISH  ;  C4L7Y4, DEF_TOLAT  ;
DR   O83738, DEF_TREPA  ;  B2S3Z6, DEF_TREPS  ;  Q83HQ3, DEF_TROW8  ;
DR   Q83GH8, DEF_TROWT  ;  B1GZ10, DEF_UNCTG  ;  B1AJA6, DEF_UREP2  ;
DR   Q9PQ25, DEF_UREPA  ;  Q5E1Q8, DEF_VIBF1  ;  B5FCW6, DEF_VIBFM  ;
DR   A7N121, DEF_VIBHB  ;  Q8D258, DEF_WIGBR  ;  Q73IJ6, DEF_WOLPM  ;
DR   B3CMB1, DEF_WOLPP  ;  Q7M7M2, DEF_WOLSU  ;  Q5GTG9, DEF_WOLTR  ;
DR   C0R5A2, DEF_WOLWR  ;  B2I8S4, DEF_XYLF2  ;  P63917, DEF_XYLFA  ;
DR   B0U4M4, DEF_XYLFM  ;  P63918, DEF_XYLFT  ;  A1JRZ1, DEF_YERE8  ;
DR   A7FNK2, DEF_YERP3  ;  Q1C2X9, DEF_YERPA  ;  B2K504, DEF_YERPB  ;
DR   Q8ZJ79, DEF_YERPE  ;  A9R927, DEF_YERPG  ;  Q1CCX6, DEF_YERPN  ;
DR   A4TH23, DEF_YERPP  ;  Q664V4, DEF_YERPS  ;  B1JJH8, DEF_YERPY  ;
DR   Q9REQ2, DEF_ZYMMO  ;
//
ID   3.5.1.89
DE   N-acetylglucosaminylphosphatidylinositol deacetylase.
AN   Acetylglucosaminylphosphatidylinositol deacetylase.
AN   GlcNAc-PI de-N-acetylase.
AN   GlcNAc-PI deacetylase.
AN   N-acetyl-D-glucosaminylphosphatidylinositol acetylhydrolase.
AN   N-acetylglucosaminylphosphatidylinositol de-N-acetylase.
CA   6-(N-acetyl-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H(2)O =
CA   6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate.
CC   -!- Involved in the second step of glycosylphosphatidylinositol (GPI)
CC       anchor formation in all eukaryotes.
CC   -!- The enzyme appears to be composed of a single subunit (PIG-L in
CC       mammalian cells and GPI12 in Saccharomyces cerevisiae).
CC   -!- In some species, the long-chain sn-1-acyl group of the phosphatidyl
CC       group is replaced by a long-chain alkyl or alk-1-enyl group.
CC   -!- Formerly EC 3.1.1.69.
DR   P23797, GPI12_YEAST;  A6QQ24, PIGL_BOVIN ;  Q54C64, PIGL_DICDI ;
DR   Q9Y2B2, PIGL_HUMAN ;  Q5SX19, PIGL_MOUSE ;  O35790, PIGL_RAT   ;
DR   Q9HDW9, PIGL_SCHPO ;
//
ID   3.5.1.90
DE   Adenosylcobinamide hydrolase.
AN   AdoCbi amidohydrolase.
AN   AdoCbi hydrolase.
CA   Adenosylcobinamide + H(2)O = adenosylcobyric acid + (R)-1-aminopropan-2-
CA   ol.
CC   -!- Involved in the salvage pathway of cobinamide in archaea.
CC   -!- Archaea convert adenosylcobinamide (AdoCbi) into adenosylcobinamide
CC       phosphate (AdoCbi-P) in two steps.
CC   -!- First, the amidohydrolase activity of cbiZ cleaves off the
CC       aminopropanol moiety of AdoCbi yielding adenosylcobyric acid
CC       (AdoCby); second, AdoCby is converted into AdoCbi-P by the action of
CC       EC 6.3.1.10 (CbiB).
DR   Q9HPK9, CBIZ_HALSA ;  Q8Q0G3, CBIZ_METMA ;
//
ID   3.5.1.91
DE   N-substituted formamide deformylase.
CA   N-benzylformamide + H(2)O = formate + benzylamine.
CF   Zinc.
CC   -!- While N-benzylformamide is the best substrate, the enzyme from
CC       Arthrobacter pascens can also act on the N-substituted formamides
CC       N-butylformamide, N-allylformamide, N-(2-(cyclohex-1-
CC       enyl)ethyl)formamide and N-(1-phenylethyl)formamide, but much more
CC       slowly.
CC   -!- Amides of other acids do not act as substrates.
DR   Q68AP4, NFDA_ARTPS ;
//
ID   3.5.1.92
DE   Pantetheine hydrolase.
AN   Pantetheinase.
AN   Vanin-1.
CA   (R)-pantetheine + H(2)O = (R)-pantothenate + 2-aminoethanethiol.
CC   -!- Hydrolyzes only one of the amide bonds of pantetheine.
CC   -!- The substrate analogs phosphopantetheine and CoA are not substrates.
CC   -!- Recycles pantothenate (vitamin B(5)) and produces cysteamine,
CC       a potent anti-oxidant.
PR   PROSITE; PDOC50263;
DR   Q58CQ9, VNN1_BOVIN ;  Q9TSX8, VNN1_CANFA ;  O95497, VNN1_HUMAN ;
DR   Q9Z0K8, VNN1_MOUSE ;  Q9BDJ5, VNN1_PIG   ;  O95498, VNN2_HUMAN ;
DR   Q9NY84, VNN3_HUMAN ;  Q9QZ25, VNN3_MOUSE ;
//
ID   3.5.1.93
DE   Glutaryl-7-aminocephalosporanic-acid acylase.
AN   7-beta-(4-carboxybutanamido)cephalosporanic acid acylase.
AN   CA.
AN   Cephalosporin acylase.
AN   Cephalosporin C acylase.
AN   GA.
AN   GCA.
AN   GL-7-ACA acylase.
AN   Glutaryl-7-ACA acylase.
AN   Glutaryl-7-aminocephalosporanic acid acylase.
CA   (7R)-7-(4-carboxybutanamido)cephalosporanate + H(2)O = (7R)-7-
CA   aminocephalosporanate + glutarate.
CC   -!- Forms 7-aminocephalosporanic acid, a key intermediate in the
CC       synthesis of cephem antibiotics.
CC   -!- It reacts only weakly with cephalosporin C.
DR   Q9L5D6, G7AC_BREDI ;  P07662, G7AC_PSEU7 ;
//
ID   3.5.1.94
DE   Gamma-glutamyl-gamma-aminobutyrate hydrolase.
AN   Gamma-glutamyl-GABA hydrolase.
CA   4-(glutamylamino)butanoate + H(2)O = 4-aminobutanoate + L-glutamate.
CC   -!- Forms part of a novel putrescine-utilizing pathway in Escherichia
CC       coli, in which it has been hypothesized that putrescine is first
CC       glutamylated to form gamma-glutamylputrescine, which is oxidized to
CC       4-(glutamylamino)butanal and then to 4-(glutamylamino)butanoate.
CC   -!- Also can catalyze the reactions of EC 3.5.1.35 and EC 3.5.1.65.
DR   Q8X7G2, PUUD_ECO57 ;  P76038, PUUD_ECOLI ;  Q83LB6, PUUD_SHIFL ;
DR   Q3Z146, PUUD_SHISS ;
//
ID   3.5.1.95
DE   N-malonylurea hydrolase.
AN   Ureidomalonase.
CA   3-oxo-3-ureidopropanoate + H(2)O = malonate + urea.
CC   -!- Forms part of the oxidative pyrimidine-degrading pathway in some
CC       microorganisms, along with EC 1.17.99.4 and EC 3.5.2.1.
//
ID   3.5.1.96
DE   Succinylglutamate desuccinylase.
AN   N(2)-succinylglutamate desuccinylase.
AN   SGDS.
CA   N-succinyl-L-glutamate + H(2)O = succinate + L-glutamate.
CF   Cobalt.
CC   -!- N(2)-acetylglutamate is not a substrate.
CC   -!- The final enzyme in the arginine succinyltransferase (AST) pathway
CC       for the catabolism of arginine.
CC   -!- This pathway converts the carbon skeleton of arginine into glutamate,
CC       with the concomitant production of ammonia and conversion of
CC       succinyl-CoA into succinate and CoA.
CC   -!- The five enzymes involved in this pathway are EC 2.3.1.109,
CC       EC 3.5.3.23, EC 2.6.1.11, EC 1.2.1.71 and EC 3.5.1.96.
DR   Q6FCP8, ASTE_ACIAD ;  B7GVV1, ASTE_ACIB3 ;  B7IA88, ASTE_ACIB5 ;
DR   B2HZS2, ASTE_ACIBC ;  B0VQ89, ASTE_ACIBS ;  A3M9D1, ASTE_ACIBT ;
DR   B0V7X4, ASTE_ACIBY ;  Q1BXN9, ASTE_BURCA ;  B1JYT7, ASTE_BURCC ;
DR   A0K610, ASTE_BURCH ;  B4ED00, ASTE_BURCJ ;  Q62LN3, ASTE_BURMA ;
DR   Q3JQC8, ASTE_BURP1 ;  Q63SD9, ASTE_BURPS ;  Q39I23, ASTE_BURS3 ;
DR   Q2SXN7, ASTE_BURTA ;  Q141D1, ASTE_BURXL ;  Q7NU26, ASTE_CHRVO ;
DR   A8AHD6, ASTE_CITK8 ;  A7ZML2, ASTE_ECO24 ;  B7USC5, ASTE_ECO27 ;
DR   B7MAV5, ASTE_ECO45 ;  B7L6L8, ASTE_ECO55 ;  Q8XDZ0, ASTE_ECO57 ;
DR   B5YQ31, ASTE_ECO5E ;  B7NT33, ASTE_ECO7I ;  B7MVM3, ASTE_ECO81 ;
DR   B7M1F6, ASTE_ECO8A ;  C4ZZA0, ASTE_ECOBW ;  B1XGK5, ASTE_ECODH ;
DR   A8A0T6, ASTE_ECOHS ;  A1ABS5, ASTE_ECOK1 ;  Q0TH86, ASTE_ECOL5 ;
DR   Q8FH03, ASTE_ECOL6 ;  B1IPI6, ASTE_ECOLC ;  P76215, ASTE_ECOLI ;
DR   B7N580, ASTE_ECOLU ;  B6IBG4, ASTE_ECOSE ;  B1LDY7, ASTE_ECOSM ;
DR   Q1RB49, ASTE_ECOUT ;  B2VEK5, ASTE_ERWT9 ;  B7LQ48, ASTE_ESCF3 ;
DR   Q5QUK3, ASTE_IDILO ;  Q7N2H1, ASTE_PHOLL ;  Q48G22, ASTE_PSE14 ;
DR   Q15TS5, ASTE_PSEA6 ;  A6VA73, ASTE_PSEA7 ;  B7UY33, ASTE_PSEA8 ;
DR   Q02I61, ASTE_PSEAB ;  O50177, ASTE_PSEAE ;  Q4K840, ASTE_PSEF5 ;
DR   C3JXY4, ASTE_PSEFS ;  Q3IGV3, ASTE_PSEHT ;  A4XWE4, ASTE_PSEMY ;
DR   A5W0D8, ASTE_PSEP1 ;  Q3K888, ASTE_PSEPF ;  B0KR44, ASTE_PSEPG ;
DR   Q88EI7, ASTE_PSEPK ;  B1JCH0, ASTE_PSEPW ;  Q885J4, ASTE_PSESM ;
DR   Q4ZQI1, ASTE_PSEU2 ;  B5F7I8, ASTE_SALA4 ;  A9MFF8, ASTE_SALAR ;
DR   Q57PX7, ASTE_SALCH ;  B5FJD4, ASTE_SALDC ;  B5QWI6, ASTE_SALEP ;
DR   B5RAZ7, ASTE_SALG2 ;  B4TGE4, ASTE_SALHS ;  B4T4K3, ASTE_SALNS ;
DR   Q5PHC2, ASTE_SALPA ;  A9N274, ASTE_SALPB ;  C0Q6X7, ASTE_SALPC ;
DR   B5BA68, ASTE_SALPK ;  B4TUC5, ASTE_SALSV ;  Q8Z6G3, ASTE_SALTI ;
DR   Q8ZPU8, ASTE_SALTY ;  A8GFQ1, ASTE_SERP5 ;  A1S6A8, ASTE_SHEAM ;
DR   B8EEX7, ASTE_SHEB2 ;  A6WNA1, ASTE_SHEB8 ;  A9L1C2, ASTE_SHEB9 ;
DR   Q12NA7, ASTE_SHEDO ;  Q082N5, ASTE_SHEFN ;  Q8EEN9, ASTE_SHEON ;
DR   A8H4T0, ASTE_SHEPA ;  A4Y6M4, ASTE_SHEPC ;  B8CPA0, ASTE_SHEPW ;
DR   A0KX43, ASTE_SHESA ;  A8FVR6, ASTE_SHESH ;  Q0HIL5, ASTE_SHESM ;
DR   Q0HVC0, ASTE_SHESR ;  A1RJV7, ASTE_SHESW ;  B1KEI0, ASTE_SHEWM ;
DR   B2U3C5, ASTE_SHIB3 ;  Q321N6, ASTE_SHIBS ;  Q32G86, ASTE_SHIDS ;
DR   Q0T4V2, ASTE_SHIF8 ;  Q7UCI6, ASTE_SHIFL ;  Q3Z292, ASTE_SHISS ;
DR   A5F1U8, ASTE_VIBC3 ;  Q9KSL4, ASTE_VIBCH ;  C3LLT8, ASTE_VIBCM ;
DR   A7MVW7, ASTE_VIBHB ;  Q87Q40, ASTE_VIBPA ;  Q8D926, ASTE_VIBVU ;
DR   Q7MLE8, ASTE_VIBVY ;  A1JS32, ASTE_YERE8 ;  A7FIL2, ASTE_YERP3 ;
DR   Q1C8A7, ASTE_YERPA ;  B2K298, ASTE_YERPB ;  Q9ZC70, ASTE_YERPE ;
DR   A9QZ59, ASTE_YERPG ;  A4TJU3, ASTE_YERPP ;  Q66B17, ASTE_YERPS ;
DR   B1JMC9, ASTE_YERPY ;
//
ID   3.5.1.97
DE   Acyl-homoserine-lactone acylase.
AN   Acyl-homoserine lactone acylase.
AN   AHL-acylase.
AN   N-acyl-homoserine lactone acylase.
AN   Quorum-quenching AHL acylase.
AN   Quorum-quenching enzyme.
CA   An N-acyl-L-homoserine lactone + H(2)O = L-homoserine lactone +
CA   a carboxylate.
CC   -!- Acyl-homoserine lactones (AHLs) are produced by a number of bacterial
CC       species and are used by them to regulate the expression of virulence
CC       genes in a process known as quorum-sensing.
CC   -!- Each bacterial cell has a basal level of AHL and, once the population
CC       density reaches a critical level, it triggers AHL-signaling which,
CC       in turn, initiates the expression of particular virulence genes.
CC   -!- Plants or animals capable of degrading AHLs would have a therapeutic
CC       advantage in avoiding bacterial infection as they could prevent AHL-
CC       signaling and the expression of virulence genes in quorum-sensing
CC       bacteria.
CC   -!- This quorum-quenching enzyme removes the fatty-acid side chain from
CC       the homoserine lactone ring of AHL-dependent quorum-sensing signal
CC       molecules.
CC   -!- It has broad specificity for AHLs with side changes ranging in length
CC       from 11 to 14 carbons.
CC   -!- Substituents at the 3'-position, as found in N-(3-oxododecanoyl)-L-
CC       homoserine lactone, do not affect this activity.
DR   Q48KB0, PVDQ_PSE14 ;  Q9I194, PVDQ_PSEAE ;  Q4KCM5, PVDQ_PSEF5 ;
DR   Q3KD51, PVDQ_PSEPF ;  Q88IU8, PVDQ_PSEPK ;  Q884D2, PVDQ_PSESM ;
DR   Q4ZV08, PVDQ_PSEU2 ;  Q48LS4, QUIP_PSE14 ;  Q9I4U2, QUIP_PSEAE ;
DR   Q4KH86, QUIP_PSEF5 ;  Q3KH00, QUIP_PSEPF ;  Q88NU6, QUIP_PSEPK ;
DR   Q87XP3, QUIP_PSESM ;  Q4ZPM1, QUIP_PSEU2 ;
//
ID   3.5.1.98
DE   Histone deacetylase.
AN   HDAC.
CA   Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a
CA   deacetylated histone.
CC   -!- A class of enzymes that remove acetyl groups from N(6)-acetyl-lysine
CC       residues on a histone.
CC   -!- The reaction of this enzyme is opposite to that of EC 2.3.1.48.
CC   -!- Histone deacetylases (HDACs) can be organized into three classes
CC       depending on sequence similarity and domain organization.
CC   -!- Histone acetylation plays an important role in regulation of gene
CC       expression.
CC   -!- In eukaryotes, HDACs play a key role in the regulation of
CC       transcription and cell proliferation.
CC   -!- May be identical to EC 3.5.1.17.
DR   P56523, CLR3_SCHPO ;  O59702, CLR6_SCHPO ;  Q9M1N8, HDA10_ARATH;
DR   Q969S8, HDA10_HUMAN;  Q6P3E7, HDA10_MOUSE;  Q569C4, HDA10_RAT  ;
DR   Q55FN5, HDA11_DICDI;  Q96DB2, HDA11_HUMAN;  Q9GKU5, HDA11_MACFA;
DR   Q91WA3, HDA11_MOUSE;  Q55BW2, HDA12_DICDI;  Q941D6, HDA14_ARATH;
DR   Q8GXJ1, HDA15_ARATH;  Q9LXN8, HDA17_ARATH;  Q8LRK8, HDA18_ARATH;
DR   O22446, HDA19_ARATH;  P56521, HDA19_MAIZE;  Q91695, HDA1A_XENLA;
DR   O42227, HDA1B_XENLA;  O17695, HDA1_CAEEL ;  P53973, HDA1_YEAST ;
DR   Q54X15, HDA21_DICDI;  Q54VQ7, HDA22_DICDI;  Q944K3, HDA2_ARATH ;
DR   Q09440, HDA2_CAEEL ;  Q613L4, HDA4_CAEBR ;  O17323, HDA4_CAEEL ;
DR   Q8RX28, HDA5_ARATH ;  Q9FML2, HDA6_ARATH ;  Q20296, HDA6_CAEEL ;
DR   Q9FH09, HDA7_ARATH ;  Q94EJ2, HDA8_ARATH ;  Q6PBI4, HDA9B_DANRE;
DR   Q8H0W2, HDA9_ARATH ;  Q32PJ8, HDAC1_BOVIN;  P56517, HDAC1_CHICK;
DR   Q94517, HDAC1_DROME;  Q13547, HDAC1_HUMAN;  O09106, HDAC1_MOUSE;
DR   Q5RAG0, HDAC1_PONAB;  Q4QQW4, HDAC1_RAT  ;  P56518, HDAC1_STRPU;
DR   P56519, HDAC2_CHICK;  Q92769, HDAC2_HUMAN;  P70288, HDAC2_MOUSE;
DR   P56520, HDAC3_CHICK;  Q803C3, HDAC3_DANRE;  O15379, HDAC3_HUMAN;
DR   O88895, HDAC3_MOUSE;  Q5RB76, HDAC3_PONAB;  Q6P6W3, HDAC3_RAT  ;
DR   Q4SFA0, HDAC3_TETNG;  Q6IRL9, HDAC3_XENLA;  Q28DV3, HDAC3_XENTR;
DR   P83038, HDAC4_CHICK;  P56524, HDAC4_HUMAN;  Q6NZM9, HDAC4_MOUSE;
DR   Q99P99, HDAC4_RAT  ;  Q80ZH1, HDAC5_CRIGR;  Q9UQL6, HDAC5_HUMAN;
DR   Q9Z2V6, HDAC5_MOUSE;  Q5R902, HDAC5_PONAB;  Q9UBN7, HDAC6_HUMAN;
DR   Q9Z2V5, HDAC6_MOUSE;  Q8WUI4, HDAC7_HUMAN;  Q8C2B3, HDAC7_MOUSE;
DR   Q99P96, HDAC7_RAT  ;  Q0VCB2, HDAC8_BOVIN;  Q7SXM0, HDAC8_DANRE;
DR   Q9BY41, HDAC8_HUMAN;  Q8VH37, HDAC8_MOUSE;  B1WC68, HDAC8_RAT  ;
DR   Q6GPA7, HDAC8_XENLA;  B1H369, HDAC8_XENTR;  Q5ZKH6, HDAC9_CHICK;
DR   Q9UKV0, HDAC9_HUMAN;  Q99N13, HDAC9_MOUSE;  Q9YGY4, HDAC9_XENLA;
DR   Q12214, HOS1_YEAST ;  P53096, HOS2_YEAST ;  Q02959, HOS3_YEAST ;
DR   O13298, PHD1_SCHPO ;  P32561, RPD3_YEAST ;
//
ID   3.5.1.99
DE   Fatty acid amide hydrolase.
AN   Anandamide amidohydrolase.
AN   Oleamide hydrolase.
CA   (1) Anandamide + H(2)O = arachidonic acid + ethanolamine.
CA   (2) Oleamide + H(2)O = oleic acid + NH(3).
CC   -!- Integral membrane protein, the enzyme is responsible for the
CC       catabolism of neuromodulatory fatty acid amides, including anandamide
CC       and oleamide, occurs in mammalia.
CC   -!- Formerly EC 3.5.1.n2.
PR   PROSITE; PDOC00494;
DR   O00519, FAAH1_HUMAN;  O08914, FAAH1_MOUSE;  Q9TUI8, FAAH1_PIG  ;
DR   P97612, FAAH1_RAT  ;  Q6GMR7, FAAH2_HUMAN;  Q6DH69, FAH2A_DANRE;
DR   Q05AM4, FAH2B_DANRE;
//
ID   3.5.1.100
DE   (R)-amidase.
AN   R-amidase.
AN   R-stereospecific amidase.
CA   (1) (R)-piperazine-2-carboxamide + H(2)O = (R)-piperazine-2-carboxylic
CA   acid + NH(3).
CA   (2) Beta-alaninamide + H(2)O = beta-alanine + NH(3).
CC   -!- In addition (R)-piperidine-3-carboxamide is hydrolyzed to (R)-
CC       piperidine-3-carboxylic acid and NH(3), and (R)-N-tert-
CC       butylpiperazine-2-carboxamide is hydrolyzed to (R)-piperazine-2-
CC       carboxylic acid and tert-butylamine with lower activity.
CC   -!- The enzyme does not act on the other amide substrates which are
CC       hydrolyzed by EC 3.5.1.4 (amidase).
PR   PROSITE; PDOC50263;
DR   Q75SP7, RSAM_PSESP ;
//
ID   3.5.1.101
DE   L-proline amide hydrolase.
AN   L-amino acid amidase.
AN   S-stereoselective piperazine-2-tert-butylcarboxamide hydrolase.
CA   (1) (S)-piperidine-2-carboxamide + H(2)O = (S)-piperidine-2-carboxylic
CA   acid + NH(3).
CA   (2) L-prolinamide + H(2)O = L-proline + NH(3).
DR   Q76KX0, LAAA_PSEAZ ;  C3K630, LAAA_PSEFS ;
//
ID   3.5.1.102
DE   2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate
DE   deformylase.
CA   2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one +
CA   H(2)O = 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one +
CA   formate.
CC   -!- The enzyme catalyzes the second step in archaeal riboflavin and 7,8-
CC       didemethyl-8-hydroxy-5-deazariboflavin biosynthesis.
CC   -!- The first step is catalyzed by EC 3.5.4.29.
CC   -!- The bacterial enzyme, EC 3.5.4.25 catalyzes both reactions.
DR   A6UUS5, ARFB_META3 ;  C7P7V6, ARFB_METFA ;  E3GWT5, ARFB_METFV ;
DR   D5VQW1, ARFB_METIM ;  Q57580, ARFB_METJA ;  A4G0L4, ARFB_METM5 ;
DR   A9A8V8, ARFB_METM6 ;  A6VHX1, ARFB_METM7 ;  Q6LWK4, ARFB_METMP ;
DR   D3E3M2, ARFB_METRM ;  A5UJL1, ARFB_METS3 ;  D3S4A5, ARFB_METSF ;
DR   Q2NF45, ARFB_METST ;  O26747, ARFB_METTH ;  D9PWM7, ARFB_METTM ;
DR   D7DV18, ARFB_METV3 ;  C9RGE3, ARFB_METVM ;  A6UQY8, ARFB_METVS ;
//
ID   3.5.1.103
DE   N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside
DE   deacetylase.
AN   1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase.
CA   1-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + H(2)O =
CA   1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + acetate.
CF   Zinc.
CC   -!- This enzyme is considered the key enzyme and rate limiting step in
CC       the mycothiol biosynthesis pathway.
CC   -!- In addition to acetylase activity, the enzyme possesses weak
CC       mycothiol conjugate amidase activity, and shares sequence similarity
CC       with mycothiol S-conjugate amidase.
CC   -!- Formerly EC 3.1.1.n1.
DR   C7Q0R3, MSHB1_CATAD;  Q0RKY6, MSHB1_FRAAA;  Q2J7C9, MSHB1_FRASC;
DR   A4F8G5, MSHB1_SACEN;  C7Q4X5, MSHB2_CATAD;  Q0RCR9, MSHB2_FRAAA;
DR   Q2J678, MSHB2_FRASC;  A4F9Z0, MSHB2_SACEN;  C7QKE2, MSHB3_CATAD;
DR   A0LW30, MSHB_ACIC1 ;  C6WKX3, MSHB_ACTMD ;  Q6NI09, MSHB_CORDI ;
DR   Q8FQG1, MSHB_COREF ;  A4QD64, MSHB_CORGB ;  Q8NRE9, MSHB_CORGL ;
DR   Q4JUD7, MSHB_CORJK ;  C4LHT4, MSHB_CORK4 ;  B1VFT1, MSHB_CORU7 ;
DR   A8L1A5, MSHB_FRASN ;  D2S9Y0, MSHB_GEOOG ;  D0LD40, MSHB_GORB4 ;
DR   A6W733, MSHB_KINRD ;  D2PN56, MSHB_KRIFD ;  A0QCB7, MSHB_MYCA1 ;
DR   B1MLH7, MSHB_MYCA9 ;  Q7U0H2, MSHB_MYCBO ;  A1KHW1, MSHB_MYCBP ;
DR   C1AMG5, MSHB_MYCBT ;  A4T907, MSHB_MYCGI ;  B8ZRQ3, MSHB_MYCLB ;
DR   Q9CBX4, MSHB_MYCLE ;  B2HSB3, MSHB_MYCMM ;  Q73WP7, MSHB_MYCPA ;
DR   A0R2I7, MSHB_MYCS2 ;  A3Q4F8, MSHB_MYCSJ ;  A1UKE3, MSHB_MYCSK ;
DR   Q1B4P5, MSHB_MYCSS ;  A5U1L9, MSHB_MYCTA ;  A5WLJ9, MSHB_MYCTF ;
DR   C6DUY7, MSHB_MYCTK ;  O50426, MSHB_MYCTU ;  A0PMQ6, MSHB_MYCUA ;
DR   A1TDR0, MSHB_MYCVP ;  C8XJN6, MSHB_NAKMY ;  D7B6L8, MSHB_NOCDD ;
DR   Q5YQD2, MSHB_NOCFA ;  A1SFT8, MSHB_NOCSJ ;  C1A2R3, MSHB_RHOE4 ;
DR   C1AZH2, MSHB_RHOOB ;  Q0S424, MSHB_RHOSR ;  C7MY07, MSHB_SACVD ;
DR   A8M3H2, MSHB_SALAI ;  A4XB95, MSHB_SALTO ;  D6ZE32, MSHB_SEGRD ;
DR   D3PW16, MSHB_STANL ;  Q82IJ5, MSHB_STRAW ;  D7BQJ3, MSHB_STRBB ;
DR   Q9F344, MSHB_STRCO ;  B1W1K9, MSHB_STRGG ;  D2B0T1, MSHB_STRRD ;
DR   C9ZBY0, MSHB_STRSW ;  D6Y7M2, MSHB_THEBD ;  D1A8M1, MSHB_THECD ;
DR   Q47SP3, MSHB_THEFY ;  D5UVX0, MSHB_TSUPD ;
//
ID   3.5.1.104
DE   Peptidoglycan-N-acetylglucosamine deacetylase.
AN   N-acetylglucosamine deacetylase.
AN   Peptidoglycan deacetylase.
AN   Peptidoglycan GlcNAc deacetylase.
AN   Peptidoglycan N-acetylglucosamine deacetylase.
CA   Peptidoglycan-N-acetyl-D-glucosamine + H(2)O = peptidoglycan-D-
CA   glucosamine + acetate.
CC   -!- Modification of peptidoglycan by N-deacetylation is an important
CC       factor in virulence of Helicobacter pylori, Listeria monocytogenes
CC       and Streptococcus suis.
CC   -!- The enzyme from Streptococcus pneumoniae is a metalloenzyme using a
CC       His-His-Asp zinc-binding triad with a nearby aspartic acid and
CC       histidine acting as the catalytic base and acid, respectively.
//
ID   3.5.1.105
DE   Chitin disaccharide deacetylase.
AN   Chitin oligosaccharide amidohydolase.
AN   Chitin oligosaccharide deacetylase.
AN   Chitobiose amidohydolase.
CA   2-(acetylamino)-4-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-2-
CA   deoxy-beta-D-glucopyranose + H(2)O = 2-(acetylamino)-4-O-(2-amino-2-
CA   deoxy-beta-D-glucopyranosyl)-2-deoxy-beta-D-glucopyranose + acetate.
CC   -!- Chitin oligosaccharide deacetylase is a key enzyme in the chitin
CC       catabolic cascade of chitinolytic Vibrio strains.
CC   -!- Besides being a nutrient, the heterodisaccharide product 4-O-
CC       (N-acetyl-beta-D-glucosaminyl)-D-glucosamine is a unique inducer of
CC       chitinase production in Vibrio parahemeolyticus.
CC   -!- In contrast to EC 3.5.1.41 this enzyme is specific for the chitin
CC       disaccharide.
CC   -!- It also deacetylates the chitin trisaccharide with lower efficiency.
CC   -!- No activity with higher polymers of GlcNAc.
//
ID   3.5.1.106
DE   N-formylmaleamate deformylase.
CA   N-formylmaleamic acid + H(2)O = maleamate + formate.
CC   -!- The reaction is involved in the aerobic catabolism of nicotinic acid.
//
ID   3.5.1.107
DE   Maleamate amidohydrolase.
CA   Maleamate + H(2)O = maleate + NH(3).
CC   -!- The reaction is involved in the aerobic catabolism of nicotinic acid.
//
ID   3.5.1.108
DE   UDP-3-O-acyl-N-acetylglucosamine deacetylase.
AN   UDP-3-O-((R)-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase.
AN   UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase.
AN   UDP-3-O-acyl-GlcNAc deacetylase.
CA   UDP-3-O-((3R)-3-hydroxytetradecanoyl)-N-acetylglucosamine + H(2)O = UDP-
CA   3-O-((3R)-3-hydroxytetradecanoyl)-D-glucosamine + acetate.
CF   Zinc.
CC   -!- The enzyme catalyzes a committed step in the biosynthesis of lipid A.
CC   -!- Formerly EC 3.5.1.n1.
//
ID   3.5.1.n1
DE   Transferred entry: 3.5.1.108.
//
ID   3.5.1.n2
DE   Transferred entry: 3.5.1.99.
//
ID   3.5.1.n3
DE   4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase.
AN   Polymyxin resistance protein PmrJ.
AN   Undecaprenyl-phosphate-alpha-L-Ara4FN deformylase.
CA   4-deoxy-4-formamido-beta-L-arabinose di-trans,poly-cis-undecaprenyl
CA   phosphate + H(2)O = 4-amino-4-deoxy-alpha-L-arabinose di-trans,poly-
CA   cis-undecaprenyl phosphate + formate.
DR   A0KGY5, ARND_AERHH ;  A4SQX0, ARND_AERS4 ;  A7ZP74, ARND_ECO24 ;
DR   B7UFR8, ARND_ECO27 ;  B7MG23, ARND_ECO45 ;  B7LAS1, ARND_ECO55 ;
DR   Q8XDZ2, ARND_ECO57 ;  B5YXP9, ARND_ECO5E ;  B7NNT5, ARND_ECO7I ;
DR   B7MXT7, ARND_ECO81 ;  B7M5T8, ARND_ECO8A ;  B1X8W9, ARND_ECODH ;
DR   A8A2C3, ARND_ECOHS ;  A1ADA8, ARND_ECOK1 ;  Q0TFI6, ARND_ECOL5 ;
DR   Q8FFM0, ARND_ECOL6 ;  B1IXT1, ARND_ECOLC ;  P76472, ARND_ECOLI ;
DR   B7N5M1, ARND_ECOLU ;  B6I7J9, ARND_ECOSE ;  B1LLL0, ARND_ECOSM ;
DR   Q1R9F9, ARND_ECOUT ;  A4WAM2, ARND_ENT38 ;  Q6D2F2, ARND_ERWCT ;
DR   B2VBI8, ARND_ERWT9 ;  B7LM75, ARND_ESCF3 ;  B5XTL0, ARND_KLEP3 ;
DR   A6TF97, ARND_KLEP7 ;  Q7N3Q8, ARND_PHOLL ;  B4ETL8, ARND_PROMH ;
DR   Q48HZ0, ARND_PSE14 ;  A6V1N9, ARND_PSEA7 ;  B7VBN1, ARND_PSEA8 ;
DR   Q02R26, ARND_PSEAB ;  Q9HY62, ARND_PSEAE ;  Q4KC81, ARND_PSEF5 ;
DR   Q3KCC0, ARND_PSEPF ;  Q4ZSZ1, ARND_PSEU2 ;  B5EZH9, ARND_SALA4 ;
DR   Q57M55, ARND_SALCH ;  B5FNU0, ARND_SALDC ;  B5R273, ARND_SALEP ;
DR   B5RCC5, ARND_SALG2 ;  B4TBG7, ARND_SALHS ;  B4SYX2, ARND_SALNS ;
DR   Q5PNA7, ARND_SALPA ;  A9N5B1, ARND_SALPB ;  C0Q068, ARND_SALPC ;
DR   B5BCP5, ARND_SALPK ;  B4TPI3, ARND_SALSV ;  Q8Z539, ARND_SALTI ;
DR   O52326, ARND_SALTY ;  A8GDR8, ARND_SERP5 ;  A8FRR1, ARND_SHESH ;
DR   B2TW39, ARND_SHIB3 ;  Q31YK1, ARND_SHIBS ;  Q32DT2, ARND_SHIDS ;
DR   Q0T2M7, ARND_SHIF8 ;  Q83KB7, ARND_SHIFL ;  Q3YZV0, ARND_SHISS ;
DR   Q2NRV8, ARND_SODGM ;  Q8D340, ARND_WIGBR ;  A1JPN1, ARND_YERE8 ;
DR   A7FHH5, ARND_YERP3 ;  Q1C743, ARND_YERPA ;  B2K5L2, ARND_YERPB ;
DR   Q7CIT9, ARND_YERPE ;  A9R092, ARND_YERPG ;  Q1CIH8, ARND_YERPN ;
DR   A4TIM5, ARND_YERPP ;  Q7BF86, ARND_YERPS ;  B1JJ31, ARND_YERPY ;
//
ID   3.5.2.1
DE   Barbiturase.
CA   Barbiturate + H(2)O = 3-oxo-3-ureidopropanoate.
CF   Zinc.
CC   -!- Specific for barbiturate as substrate.
CC   -!- Forms part of the oxidative pyrimidine-degrading pathway in some
CC       microorganisms, along with EC 1.17.99.4 and EC 3.5.1.95.
CC   -!- It was previously thought that the end-products of the reaction were
CC       malonate and urea.
CC   -!- May be involved in the regulation of pyrimidine metabolism, along
CC       with EC 2.4.2.9.
DR   Q8RSQ2, BAR_RHOER  ;
//
ID   3.5.2.2
DE   Dihydropyrimidinase.
AN   Hydantoinase.
CA   5,6-dihydrouracil + H(2)O = 3-ureidopropanoate.
CC   -!- Also acts on dihydrothymine and hydantoin.
DR   Q60Q85, DHP1_CAEBR ;  Q21773, DHP1_CAEEL ;  Q61YQ1, DHP2_CAEBR ;
DR   Q18677, DHP2_CAEEL ;  Q55DL0, DPYS_DICDI ;  Q14117, DPYS_HUMAN ;
DR   Q9EQF5, DPYS_MOUSE ;  Q63150, DPYS_RAT   ;  Q9P903, DPYS_SACKL ;
DR   Q9I676, HYDA_PSEAE ;  Q59699, HYDA_PSEPU ;
//
ID   3.5.2.3
DE   Dihydroorotase.
AN   Carbamoylaspartic dehydrase.
AN   DHOase.
CA   (S)-dihydroorotate + H(2)O = N-carbamoyl-L-aspartate.
PR   PROSITE; PDOC00401;
DR   P20054, PYR1_DICDI ;  P05990, PYR1_DROME ;  P27708, PYR1_HUMAN ;
DR   P08955, PYR1_MESAU ;  Q91437, PYR1_SQUAC ;  B0CF78, PYRC_ACAM1 ;
DR   Q6FD29, PYRC_ACIAD ;  B7GX48, PYRC_ACIB3 ;  B7I9G6, PYRC_ACIB5 ;
DR   B2HWF6, PYRC_ACIBC ;  B0VKW9, PYRC_ACIBS ;  A3M3K3, PYRC_ACIBT ;
DR   B0VAC1, PYRC_ACIBY ;  A1WC79, PYRC_ACISJ ;  Q9YFI5, PYRC_AERPE ;
DR   B9J8H5, PYRC_AGRRK ;  Q8UI99, PYRC_AGRT5 ;  B9JQV9, PYRC_AGRVS ;
DR   Q0VNK6, PYRC_ALCBS ;  Q0AB36, PYRC_ALHEH ;  B6ER91, PYRC_ALISL ;
DR   B4RRN5, PYRC_ALTMD ;  B8JAE8, PYRC_ANAD2 ;  Q2IIB0, PYRC_ANADE ;
DR   Q2GL89, PYRC_ANAPZ ;  B4UDQ2, PYRC_ANASK ;  B9MS22, PYRC_ANATD ;
DR   B7GFA5, PYRC_ANOFW ;  O66990, PYRC_AQUAE ;  O04904, PYRC_ARATH ;
DR   O28034, PYRC_ARCFU ;  Q5P6Y5, PYRC_AROAE ;  A1K3T5, PYRC_AZOSB ;
DR   C1DQV1, PYRC_AZOVD ;  C3P658, PYRC_BACAA ;  C3L738, PYRC_BACAC ;
DR   A0RHR0, PYRC_BACAH ;  Q81WF0, PYRC_BACAN ;  B7JJX5, PYRC_BACC0 ;
DR   Q732I1, PYRC_BACC1 ;  B7IUP8, PYRC_BACC2 ;  C1EPQ2, PYRC_BACC3 ;
DR   B7H6M4, PYRC_BACC4 ;  B7HLM2, PYRC_BACC7 ;  P46538, PYRC_BACCL ;
DR   A7GRL3, PYRC_BACCN ;  B9IVW5, PYRC_BACCQ ;  Q819S1, PYRC_BACCR ;
DR   Q636D8, PYRC_BACCZ ;  Q9K9V7, PYRC_BACHD ;  Q6HES6, PYRC_BACHK ;
DR   Q65JU9, PYRC_BACLD ;  A8FD15, PYRC_BACP2 ;  Q5WFJ0, PYRC_BACSK ;
DR   P25995, PYRC_BACSU ;  A9VTC8, PYRC_BACWK ;  C0ZG41, PYRC_BREBN ;
DR   B8D9C1, PYRC_BUCA5 ;  P57416, PYRC_BUCAI ;  Q8K9L2, PYRC_BUCAP ;
DR   B8D7M3, PYRC_BUCAT ;  A4XKT2, PYRC_CALS8 ;  Q3AC01, PYRC_CARHZ ;
DR   Q8KDK5, PYRC_CHLTE ;  A8AI14, PYRC_CITK8 ;  Q97LN7, PYRC_CLOAB ;
DR   B2UW91, PYRC_CLOBA ;  B2TNG1, PYRC_CLOBB ;  B8I770, PYRC_CLOCE ;
DR   Q18C47, PYRC_CLOD6 ;  A3DE07, PYRC_CLOTH ;  Q8NQ39, PYRC_CORGL ;
DR   A9NA67, PYRC_COXBR ;  Q0KEE2, PYRC_CUPNH ;  Q475T7, PYRC_CUPPJ ;
DR   B2AH54, PYRC_CUPTR ;  Q9RVC3, PYRC_DEIRA ;  A9BSM4, PYRC_DELAS ;
DR   C0QJ54, PYRC_DESAH ;  Q6AS41, PYRC_DESPS ;  A4J556, PYRC_DESRM ;
DR   A7ZKG7, PYRC_ECO24 ;  B7UP76, PYRC_ECO27 ;  B7MIK3, PYRC_ECO45 ;
DR   B7LFZ6, PYRC_ECO55 ;  Q8X8N8, PYRC_ECO57 ;  B5YVT2, PYRC_ECO5E ;
DR   B7NL72, PYRC_ECO7I ;  B7MTJ3, PYRC_ECO81 ;  B7M937, PYRC_ECO8A ;
DR   C4ZS02, PYRC_ECOBW ;  B1X9H5, PYRC_ECODH ;  A7ZZ20, PYRC_ECOHS ;
DR   A1A9V7, PYRC_ECOK1 ;  Q0TJ12, PYRC_ECOL5 ;  Q8FIR2, PYRC_ECOL6 ;
DR   B1IV40, PYRC_ECOLC ;  P05020, PYRC_ECOLI ;  B7NAT7, PYRC_ECOLU ;
DR   B6I9D9, PYRC_ECOSE ;  B1LIU8, PYRC_ECOSM ;  Q1RD95, PYRC_ECOUT ;
DR   C5BA73, PYRC_EDWI9 ;  Q3YRI2, PYRC_EHRCJ ;  Q2GH90, PYRC_EHRCR ;
DR   B2KCN5, PYRC_ELUMP ;  A4W975, PYRC_ENT38 ;  Q834E0, PYRC_ENTFA ;
DR   A7MG30, PYRC_ENTS8 ;  Q6D698, PYRC_ERWCT ;  B2VDJ8, PYRC_ERWT9 ;
DR   Q2NCC9, PYRC_ERYLH ;  B7LT74, PYRC_ESCF3 ;  Q8RG88, PYRC_FUSNN ;
DR   B5EB50, PYRC_GEOBB ;  Q5L0U5, PYRC_GEOKA ;  B3E3I1, PYRC_GEOLS ;
DR   Q39US3, PYRC_GEOMG ;  B9M4S4, PYRC_GEOSF ;  Q74DP4, PYRC_GEOSL ;
DR   C6DZ51, PYRC_GEOSM ;  C5D8P8, PYRC_GEOSW ;  A4IM31, PYRC_GEOTN ;
DR   A5GF42, PYRC_GEOUR ;  Q2SCE3, PYRC_HAHCH ;  A1WV00, PYRC_HALHL ;
DR   Q9HMH9, PYRC_HALSA ;  Q17W17, PYRC_HELAH ;  Q7VIJ1, PYRC_HELHP ;
DR   B6JLG3, PYRC_HELP2 ;  B5Z6V2, PYRC_HELPG ;  Q1CTU5, PYRC_HELPH ;
DR   Q9ZLQ0, PYRC_HELPJ ;  B2UTP7, PYRC_HELPS ;  P56465, PYRC_HELPY ;
DR   Q5QWC6, PYRC_IDILO ;  Q28RK3, PYRC_JANSC ;  B5XXJ5, PYRC_KLEP3 ;
DR   A6T7D6, PYRC_KLEP7 ;  Q5FJB8, PYRC_LACAC ;  Q1G867, PYRC_LACDA ;
DR   Q047M6, PYRC_LACDB ;  B2GD08, PYRC_LACF3 ;  Q043B0, PYRC_LACGA ;
DR   A8YVZ5, PYRC_LACH4 ;  Q74J32, PYRC_LACJO ;  Q9CGM7, PYRC_LACLA ;
DR   P48795, PYRC_LACLE ;  P77884, PYRC_LACPL ;  Q1WVB1, PYRC_LACS1 ;
DR   Q38X26, PYRC_LACSS ;  C1D672, PYRC_LARHH ;  Q6AF87, PYRC_LEIXX ;
DR   B1XWS5, PYRC_LEPCP ;  Q92AH1, PYRC_LISIN ;  C1KWD6, PYRC_LISMC ;
DR   Q71YH9, PYRC_LISMF ;  B8DDR5, PYRC_LISMH ;  Q8Y663, PYRC_LISMO ;
DR   A0AJU2, PYRC_LISW6 ;  B1HQB9, PYRC_LYSSC ;  B9EB67, PYRC_MACCJ ;
DR   A1U3L1, PYRC_MARAV ;  A6VXW9, PYRC_MARMS ;  Q11IA4, PYRC_MESSB ;
DR   Q8TSA6, PYRC_METAC ;  Q1GYZ0, PYRC_METFK ;  Q58885, PYRC_METJA ;
DR   Q8TXX9, PYRC_METKA ;  Q8PVF4, PYRC_METMA ;  Q2NHZ6, PYRC_METST ;
DR   O27199, PYRC_METTH ;  B0JQJ1, PYRC_MICAN ;  Q7U057, PYRC_MYCBO ;
DR   Q9CCR4, PYRC_MYCLE ;  P71809, PYRC_MYCTU ;  Q5F9Y1, PYRC_NEIG1 ;
DR   B4RJT2, PYRC_NEIG2 ;  A9M2W6, PYRC_NEIM0 ;  Q9JVD6, PYRC_NEIMA ;
DR   Q9K0D1, PYRC_NEIMB ;  A1KSU5, PYRC_NEIMF ;  Q0AFI1, PYRC_NITEC ;
DR   Q82WF3, PYRC_NITEU ;  Q3J872, PYRC_NITOC ;  Q2G9U3, PYRC_NOVAD ;
DR   C6DKU3, PYRC_PECCP ;  Q03HB2, PYRC_PEDPA ;  Q3A449, PYRC_PELCD ;
DR   A1AS12, PYRC_PELPD ;  A5D1A4, PYRC_PELTS ;  Q7N5W0, PYRC_PHOLL ;
DR   Q6LPI7, PYRC_PHOPR ;  Q48F12, PYRC_PSE14 ;  Q15YC5, PYRC_PSEA6 ;
DR   A6V1R9, PYRC_PSEA7 ;  B7UVV3, PYRC_PSEA8 ;  Q02QZ8, PYRC_PSEAB ;
DR   P72170, PYRC_PSEAE ;  Q1IE05, PYRC_PSEE4 ;  Q4K747, PYRC_PSEF5 ;
DR   C3KBZ0, PYRC_PSEFS ;  A4XS41, PYRC_PSEMY ;  A5VZH8, PYRC_PSEP1 ;
DR   Q3K7J8, PYRC_PSEPF ;  B0KUE9, PYRC_PSEPG ;  Q88NW7, PYRC_PSEPK ;
DR   B1J4I2, PYRC_PSEPW ;  Q87XM1, PYRC_PSESM ;  Q4ZPJ8, PYRC_PSEU2 ;
DR   A4VIU5, PYRC_PSEU5 ;  A1SX20, PYRC_PSYIN ;  Q9UXV6, PYRC_PYRAB ;
DR   Q8ZZC7, PYRC_PYRAE ;  Q8U4A0, PYRC_PYRFU ;  O57740, PYRC_PYRHO ;
DR   Q5JJ91, PYRC_PYRKO ;  Q1LRD4, PYRC_RALME ;  B2UFJ8, PYRC_RALPJ ;
DR   Q8Y249, PYRC_RALSO ;  B3Q0A1, PYRC_RHIE6 ;  Q2KCZ6, PYRC_RHIEC ;
DR   Q1MM16, PYRC_RHIL3 ;  B5ZNS1, PYRC_RHILW ;  Q92SC7, PYRC_RHIME ;
DR   C3MF80, PYRC_RHISN ;  Q7UNR2, PYRC_RHOBA ;  A4WPB7, PYRC_RHOS5 ;
DR   Q163V6, PYRC_ROSDO ;  Q1AVY7, PYRC_RUBXD ;  B5F944, PYRC_SALA4 ;
DR   A9MH00, PYRC_SALAR ;  Q57QJ4, PYRC_SALCH ;  B5FL01, PYRC_SALDC ;
DR   B5QY02, PYRC_SALEP ;  B5RBD7, PYRC_SALG2 ;  B4TET5, PYRC_SALHS ;
DR   B4T2Z5, PYRC_SALNS ;  Q5PGW5, PYRC_SALPA ;  A9N5P9, PYRC_SALPB ;
DR   C0Q845, PYRC_SALPC ;  B5BBC6, PYRC_SALPK ;  B4TSS5, PYRC_SALSV ;
DR   Q8Z7L2, PYRC_SALTI ;  P06204, PYRC_SALTY ;  Q9UTI0, PYRC_SCHPO ;
DR   Q9S3S1, PYRC_SERMA ;  A8GD09, PYRC_SERP5 ;  A1S9L6, PYRC_SHEAM ;
DR   B8E4P5, PYRC_SHEB2 ;  A3D7V9, PYRC_SHEB5 ;  A6WK08, PYRC_SHEB8 ;
DR   A9L3F5, PYRC_SHEB9 ;  Q12NL3, PYRC_SHEDO ;  Q087W5, PYRC_SHEFN ;
DR   B0TRS6, PYRC_SHEHH ;  A3QAV2, PYRC_SHELP ;  Q8EB40, PYRC_SHEON ;
DR   A8H7J4, PYRC_SHEPA ;  A4Y9S5, PYRC_SHEPC ;  B8CT15, PYRC_SHEPW ;
DR   A0L0B8, PYRC_SHESA ;  A8FZC6, PYRC_SHESH ;  Q0HLX7, PYRC_SHESM ;
DR   Q0HRV9, PYRC_SHESR ;  A1RGK8, PYRC_SHESW ;  B1KEK5, PYRC_SHEWM ;
DR   B2TTK9, PYRC_SHIB3 ;  Q31ZB7, PYRC_SHIBS ;  Q32ES3, PYRC_SHIDS ;
DR   Q0T5X0, PYRC_SHIF8 ;  Q83RT8, PYRC_SHIFL ;  Q3Z354, PYRC_SHISS ;
DR   Q5LQ43, PYRC_SILPO ;  Q1GFQ7, PYRC_SILST ;  A6U5N6, PYRC_SINMW ;
DR   Q01V55, PYRC_SOLUE ;  Q1GT81, PYRC_SPHAL ;  Q5HGN1, PYRC_STAAC ;
DR   P65905, PYRC_STAAM ;  P65906, PYRC_STAAN ;  Q6GHN4, PYRC_STAAR ;
DR   Q6GA12, PYRC_STAAS ;  P65907, PYRC_STAAW ;  Q5HPZ0, PYRC_STAEQ ;
DR   Q8CPJ6, PYRC_STAES ;  Q9KXR3, PYRC_STRCO ;  Q9A071, PYRC_STRP1 ;
DR   P0DD64, PYRC_STRP3 ;  Q5XCK2, PYRC_STRP6 ;  Q7CNB0, PYRC_STRP8 ;
DR   Q97QN4, PYRC_STRPN ;  P0DD65, PYRC_STRPQ ;  Q8DPQ5, PYRC_STRR6 ;
DR   Q5LZQ6, PYRC_STRT1 ;  Q5M4C1, PYRC_STRT2 ;  O08357, PYRC_SULAC ;
DR   Q9UX05, PYRC_SULSO ;  B2V5I6, PYRC_SULSY ;  Q970X5, PYRC_SULTO ;
DR   Q2LVI3, PYRC_SYNAS ;  A0LK22, PYRC_SYNFM ;  B1XI96, PYRC_SYNP2 ;
DR   Q7U618, PYRC_SYNPX ;  A5GR03, PYRC_SYNR3 ;  Q3AYG9, PYRC_SYNS9 ;
DR   Q3AKY8, PYRC_SYNSC ;  P74438, PYRC_SYNY3 ;  C5BNK6, PYRC_TERTT ;
DR   Q9HIM0, PYRC_THEAC ;  P96081, PYRC_THEAQ ;  Q9WYH0, PYRC_THEMA ;
DR   B0KA35, PYRC_THEP3 ;  B0K2E8, PYRC_THEPX ;  Q8R9R6, PYRC_THETN ;
DR   Q97C35, PYRC_THEVO ;  B1GYY7, PYRC_UNCTG ;  P31301, PYRC_USTMA ;
DR   C5CMK6, PYRC_VARPS ;  Q9KL24, PYRC_VIBCH ;  Q5E0G4, PYRC_VIBF1 ;
DR   B5ETI9, PYRC_VIBFM ;  A7N655, PYRC_VIBHB ;  Q87J46, PYRC_VIBPA ;
DR   B7VQP0, PYRC_VIBSL ;  Q8D3T9, PYRC_VIBVU ;  Q7MFB3, PYRC_VIBVY ;
DR   Q5GSJ0, PYRC_WOLTR ;  C0R5K8, PYRC_WOLWR ;  P20051, PYRC_YEAST ;
DR   A1JN45, PYRC_YERE8 ;  A7FH16, PYRC_YERP3 ;  Q1C6L6, PYRC_YERPA ;
DR   B2K767, PYRC_YERPB ;  Q8ZFU4, PYRC_YERPE ;  A9R7Y6, PYRC_YERPG ;
DR   Q1CI09, PYRC_YERPN ;  A4TLT2, PYRC_YERPP ;  Q669K2, PYRC_YERPS ;
DR   B1JHH4, PYRC_YERPY ;
//
ID   3.5.2.4
DE   Carboxymethylhydantoinase.
CA   L-5-carboxymethylhydantoin + H(2)O = N-carbamoyl-L-aspartate.
//
ID   3.5.2.5
DE   Allantoinase.
CA   (S)-allantoin + H(2)O = allantoate.
PR   PROSITE; PDOC00401;
DR   A7Z8F5, ALLB_BACA2 ;  Q9KAH8, ALLB_BACHD ;  Q65LN0, ALLB_BACLD ;
DR   Q5WBJ6, ALLB_BACSK ;  O32137, ALLB_BACSU ;  Q1J391, ALLB_DEIGD ;
DR   Q9RV76, ALLB_DEIRA ;  B8G120, ALLB_DESHD ;  Q24PT9, ALLB_DESHY ;
DR   A7ZIR8, ALLB_ECO24 ;  B7UKI9, ALLB_ECO27 ;  B7ME34, ALLB_ECO45 ;
DR   B7L7D8, ALLB_ECO55 ;  B7MQM2, ALLB_ECO81 ;  B7M4L5, ALLB_ECO8A ;
DR   C4ZUW1, ALLB_ECOBW ;  B1XGB0, ALLB_ECODH ;  A7ZXG5, ALLB_ECOHS ;
DR   A1A8H7, ALLB_ECOK1 ;  Q0TKD0, ALLB_ECOL5 ;  Q8FK60, ALLB_ECOL6 ;
DR   B1IZ89, ALLB_ECOLC ;  P77671, ALLB_ECOLI ;  B7N966, ALLB_ECOLU ;
DR   B6I0G2, ALLB_ECOSE ;  B1LKD0, ALLB_ECOSM ;  Q1RF23, ALLB_ECOUT ;
DR   Q82ZQ1, ALLB_ENTFA ;  Q1AS71, ALLB_RUBXD ;  B5EYC3, ALLB_SALA4 ;
DR   Q57S43, ALLB_SALCH ;  B5FLN3, ALLB_SALDC ;  B5QUT6, ALLB_SALEP ;
DR   B5R646, ALLB_SALG2 ;  B4T9L5, ALLB_SALHS ;  B4SXM8, ALLB_SALNS ;
DR   Q5PCG0, ALLB_SALPA ;  A9MW45, ALLB_SALPB ;  B5BD11, ALLB_SALPK ;
DR   Q8XGS6, ALLB_SALTI ;  Q7CR08, ALLB_SALTY ;  Q02C42, ALLB_SOLUE ;
DR   Q82LL4, ALLB_STRAW ;  Q9RKU5, ALLB_STRCO ;  Q54SV3, ALN1_DICDI ;
DR   Q55C91, ALN2_DICDI ;  P40757, ALN_RANCA  ;  P32375, ALN_YEAST  ;
//
ID   3.5.2.6
DE   Beta-lactamase.
AN   Cephalosporinase.
AN   Penicillinase.
CA   A beta-lactam + H(2)O = a substituted beta-amino acid.
CF   Zinc.
CC   -!- Zinc is only requires in class-B enzymes.
CC   -!- A group of enzymes of varying specificity hydrolyzing beta-lactams;
CC       some act more rapidly on penicillins, some more rapidly on
CC       cephalosporins.
CC   -!- Formerly EC 3.5.2.8.
PR   PROSITE; PDOC00134;
PR   PROSITE; PDOC00606;
DR   P05193, AMPC_CITFR ;  P00811, AMPC_ECOLI ;  P05364, AMPC_ENTCL ;
DR   Q48743, AMPC_LYSLA ;  P94958, AMPC_MORMO ;  O69773, AMPC_PROST ;
DR   P24735, AMPC_PSEAE ;  P85302, AMPC_PSEFL ;  O05465, AMPC_PSYIM ;
DR   P18539, AMPC_SERMA ;  P45460, AMPC_YEREN ;  Q9S424, BLA13_KLEPN;
DR   P67920, BLA1_ACTPL ;  Q44056, BLA1_AERHY ;  P10424, BLA1_BACCE ;
DR   P28018, BLA1_BACMY ;  P0AD63, BLA1_ECOLX ;  P18251, BLA1_ENTCL ;
DR   P67918, BLA1_HAEIF ;  P0AD64, BLA1_KLEPN ;  Q59514, BLA1_MORCA ;
DR   P67919, BLA1_PASHA ;  P52700, BLA1_STEMA ;  Q03680, BLA1_STRCI ;
DR   Q9S169, BLA24_ECOLX;  Q9AHN9, BLA29_KLEPN;  P10425, BLA2_BAC17 ;
DR   P04190, BLA2_BACCE ;  P0A9Z7, BLA2_ECOLX ;  P0A9Z8, BLA2_KLEPN ;
DR   P0A9Z9, BLA2_KLEPO ;  P0AA00, BLA2_SALTY ;  P96465, BLA2_STEMA ;
DR   P14560, BLA2_STRCI ;  Q93LM8, BLA34_ECOLX;  P06548, BLA3_BACCE ;
DR   P30896, BLA3_KLEPN ;  Q848S4, BLA46_KLEOX;  P37323, BLA4_KLEPN ;
DR   P0A3M1, BLA5_KLEPN ;  P0A3M2, BLA5_PSEAE ;  P96348, BLA6_KLEPN ;
DR   O08337, BLA8_ECOLX ;  O08498, BLAB1_FLAME;  Q9RB01, BLAB2_FLAME;
DR   Q9K303, BLAB3_FLAME;  Q9XBN7, BLAB4_FLAME;  Q9KJA9, BLAB5_FLAME;
DR   Q9KJB0, BLAB6_FLAME;  Q9KJA8, BLAB7_FLAME;  Q9KJA7, BLAB8_FLAME;
DR   P26918, BLAB_AERHY ;  P14488, BLAB_BACCE ;  P25910, BLAB_BACFR ;
DR   P52664, BLAB_PROVU ;  P52699, BLAB_SERMA ;  Q44674, BLAC_BACAM ;
DR   P00809, BLAC_BACCE ;  P00808, BLAC_BACLI ;  P39824, BLAC_BACSU ;
DR   Q45726, BLAC_BACTU ;  P30898, BLAC_BACUN ;  P30899, BLAC_BACVU ;
DR   P22390, BLAC_CITDI ;  P05192, BLAC_KLEPN ;  P0A5I7, BLAC_MYCBO ;
DR   A5U493, BLAC_MYCTA ;  P0C5C1, BLAC_MYCTU ;  Q9EZQ7, BLAC_NOCAS ;
DR   Q5YXD6, BLAC_NOCFA ;  Q06316, BLAC_NOCLA ;  P30897, BLAC_PROMI ;
DR   P80298, BLAC_PROVU ;  P14171, BLAC_RHOCA ;  P80545, BLAC_SERFO ;
DR   P00807, BLAC_STAAU ;  P14559, BLAC_STRAL ;  P10509, BLAC_STRAU ;
DR   P35391, BLAC_STRBA ;  Q06650, BLAC_STRCE ;  P35392, BLAC_STRFR ;
DR   P81173, BLAC_STRGR ;  P35393, BLAC_STRLA ;  Q01166, BLAC_YEREN ;
DR   Q59517, BLAF_MYCFO ;  C7C422, BLAN1_KLEPN;  P52663, BLAN_ENTCL ;
DR   P52682, BLAN_SERMA ;  P62593, BLAT_ECOLX ;  Q48406, BLAT_KLEOX ;
DR   P62594, BLAT_SALTI ;  P28585, BLC1_ECOLX ;  P74841, BLC2_SALTY ;
DR   P37322, BLC3_PSEAE ;  Q51355, BLC4_PSEAE ;  O33807, BLC4_SALTY ;
DR   O65975, BLC5_SALTY ;  O65976, BLC6_SALTY ;  P81781, BLC6_VIBCH ;
DR   P37321, BLE1_PSEAE ;  Q848S6, BLKPC_KLEOX;  Q9F663, BLKPC_KLEPN;
DR   Q00983, BLL1_PSEAE ;  P14489, BLO10_PSEAE;  Q06778, BLO11_PSEAE;
DR   Q51574, BLO15_PSEAE;  O07293, BLO18_PSEAE;  Q9R976, BLO19_PSEAE;
DR   P13661, BLO1_ECOLX ;  P22391, BLO1_KLEOX ;  O84955, BLO20_PSEAE;
DR   P0A1V9, BLO2_ECOLX ;  P23954, BLO2_KLEOX ;  P0A1V8, BLO2_SALTY ;
DR   Q51429, BLO3_PSEAE ;  Q00982, BLO5_PSEAE ;  P35695, BLO7_ECOLX ;
DR   P0A3M4, BLO9_ENTAE ;  P0A3M3, BLO9_KLEPN ;  Q03170, BLP1_PSEAE ;
DR   P16897, BLP4_PSEAE ;  Q47066, BLT1_ECOLX ;  O69395, BLT2_ECOLX ;
DR   P0AEB2, DACA_ECOLI ;  Q9ZMM1, HCPA_HELPJ ;  O25001, HCPA_HELPY ;
DR   O25103, HCPB_HELPY ;  Q9ZKB5, HCPC_HELPJ ;  O25728, HCPC_HELPY ;
DR   Q9ZMS0, HCPD_HELPJ ;  O24968, HCPD_HELPY ;  Q9ZMJ9, HCPE_HELPJ ;
DR   O25021, HCPE_HELPY ;  Q02940, PENA_BURM1 ;  P54427, YBXI_BACSU ;
//
ID   3.5.2.7
DE   Imidazolonepropionase.
AN   4(5)-imidazolone-5(4)-propionic acid hydrolase.
AN   Imidazolone propionic acid hydrolase.
AN   Imidazolone-5-propionate hydrolase.
CA   (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate + H(2)O =
CA   N-formimidoyl-L-glutamate + H(+).
DR   Q8YD09, HUTIH_BRUME;  A1TRE0, HUTI_ACIAC ;  B7GUU8, HUTI_ACIB3 ;
DR   B7I268, HUTI_ACIB5 ;  B2I2C1, HUTI_ACIBC ;  A3MA48, HUTI_ACIBT ;
DR   A5FZB8, HUTI_ACICJ ;  A0KF84, HUTI_AERHH ;  A4SSN5, HUTI_AERS4 ;
DR   Q9KWE5, HUTI_AGRRH ;  Q8U8Z6, HUTI_AGRT5 ;  B6ERX5, HUTI_ALISL ;
DR   A6TSW9, HUTI_ALKMQ ;  A8MF65, HUTI_ALKOO ;  B4RW95, HUTI_ALTMD ;
DR   B8JBF9, HUTI_ANAD2 ;  Q2IHZ6, HUTI_ANADE ;  B4UEL6, HUTI_ANASK ;
DR   Q5NZY0, HUTI_AROAE ;  A1R4S6, HUTI_ARTAT ;  A0JUI7, HUTI_ARTS2 ;
DR   A7ZAE6, HUTI_BACA2 ;  C3P4M0, HUTI_BACAA ;  C3L984, HUTI_BACAC ;
DR   A0RH37, HUTI_BACAH ;  Q81Y47, HUTI_BACAN ;  B7JI78, HUTI_BACC0 ;
DR   Q733I0, HUTI_BACC1 ;  B7ISJ0, HUTI_BACC2 ;  C1EN91, HUTI_BACC3 ;
DR   B7HCC8, HUTI_BACC4 ;  B7HKI9, HUTI_BACC7 ;  A7GQZ8, HUTI_BACCN ;
DR   B9IUG8, HUTI_BACCQ ;  Q81AC8, HUTI_BACCR ;  Q637I0, HUTI_BACCZ ;
DR   Q5L8E4, HUTI_BACFN ;  Q64NP4, HUTI_BACFR ;  Q9KBE4, HUTI_BACHD ;
DR   Q6HFF1, HUTI_BACHK ;  Q5WCP8, HUTI_BACSK ;  P42084, HUTI_BACSU ;
DR   Q8A4B1, HUTI_BACTN ;  A6KX92, HUTI_BACV8 ;  A9VPT6, HUTI_BACWK ;
DR   Q6MJP9, HUTI_BDEBA ;  A5PJV3, HUTI_BOVIN ;  Q89GV2, HUTI_BRAJA ;
DR   A5EQB8, HUTI_BRASB ;  A4YNK6, HUTI_BRASO ;  C0ZHT2, HUTI_BREBN ;
DR   B2SD97, HUTI_BRUA1 ;  Q2YIL5, HUTI_BRUA2 ;  Q579E7, HUTI_BRUAB ;
DR   A5VVJ5, HUTI_BRUO2 ;  A9WVU2, HUTI_BRUSI ;  Q8FVB5, HUTI_BRUSU ;
DR   B1YT76, HUTI_BURA4 ;  Q1BHY1, HUTI_BURCA ;  B1JV46, HUTI_BURCC ;
DR   A0K8U2, HUTI_BURCH ;  B4EDX1, HUTI_BURCJ ;  Q0BDL0, HUTI_BURCM ;
DR   A9AGQ1, HUTI_BURM1 ;  Q62LJ2, HUTI_BURMA ;  A3NX99, HUTI_BURP0 ;
DR   Q3JQH7, HUTI_BURP1 ;  A3NBG6, HUTI_BURP6 ;  B2JCJ1, HUTI_BURP8 ;
DR   B2T2Y6, HUTI_BURPP ;  Q63SI0, HUTI_BURPS ;  Q39EP4, HUTI_BURS3 ;
DR   Q2SXJ3, HUTI_BURTA ;  Q141F5, HUTI_BURXL ;  B8H2S2, HUTI_CAUCN ;
DR   P58079, HUTI_CAUCR ;  B0SYU7, HUTI_CAUSK ;  B8GA45, HUTI_CHLAD ;
DR   Q7P192, HUTI_CHRVO ;  Q891P9, HUTI_CLOTE ;  Q487V5, HUTI_COLP3 ;
DR   Q0K7D1, HUTI_CUPNH ;  Q46XQ9, HUTI_CUPPJ ;  B3R6A3, HUTI_CUPTR ;
DR   Q7SXK5, HUTI_DANRE ;  C1CWB5, HUTI_DEIDV ;  Q9RZ05, HUTI_DEIRA ;
DR   Q6AKP5, HUTI_DESPS ;  Q55CY3, HUTI_DICDI ;  B2VC08, HUTI_ERWT9 ;
DR   A5FB49, HUTI_FLAJ1 ;  A6H0H4, HUTI_FLAPJ ;  Q8RFG1, HUTI_FUSNN ;
DR   Q5L083, HUTI_GEOKA ;  C5DA20, HUTI_GEOSW ;  A4IMP4, HUTI_GEOTN ;
DR   Q5FRS2, HUTI_GLUOX ;  A0LZE0, HUTI_GRAFK ;  Q2SEP8, HUTI_HAHCH ;
DR   Q5V1C1, HUTI_HALMA ;  B0R543, HUTI_HALS3 ;  Q9HQD6, HUTI_HALSA ;
DR   A9AW17, HUTI_HERA2 ;  Q96NU7, HUTI_HUMAN ;  Q0BZK3, HUTI_HYPNA ;
DR   Q5QV40, HUTI_IDILO ;  B5XZ83, HUTI_KLEP3 ;  A6T6K7, HUTI_KLEP7 ;
DR   C5CFQ7, HUTI_KOSOT ;  Q5X739, HUTI_LEGPA ;  A5IGJ7, HUTI_LEGPC ;
DR   Q5ZXM0, HUTI_LEGPH ;  Q5WYI8, HUTI_LEGPL ;  Q0AP91, HUTI_MARMM ;
DR   Q11E17, HUTI_MESSB ;  B8II09, HUTI_METNO ;  B0UQ16, HUTI_METS4 ;
DR   C5C8I6, HUTI_MICLC ;  Q9DBA8, HUTI_MOUSE ;  A0QRN6, HUTI_MYCS2 ;
DR   Q1D4A5, HUTI_MYXXD ;  A7RX26, HUTI_NEMVE ;  Q5Z0G2, HUTI_NOCFA ;
DR   A1SPZ7, HUTI_NOCSJ ;  A6WYU9, HUTI_OCHA4 ;  A6LI30, HUTI_PARD8 ;
DR   A1AZX8, HUTI_PARDP ;  Q7N291, HUTI_PHOLL ;  Q6LQ59, HUTI_PHOPR ;
DR   Q6L2W1, HUTI_PICTO ;  Q12EQ4, HUTI_POLSJ ;  B2RLA8, HUTI_PORG3 ;
DR   Q7MX82, HUTI_PORGI ;  Q6A5T8, HUTI_PROAC ;  Q48CD3, HUTI_PSE14 ;
DR   Q15X43, HUTI_PSEA6 ;  A6VDL0, HUTI_PSEA7 ;  B7V3I5, HUTI_PSEA8 ;
DR   Q02ES4, HUTI_PSEAB ;  Q9HU91, HUTI_PSEAE ;  Q1I3R1, HUTI_PSEE4 ;
DR   Q4KJN0, HUTI_PSEF5 ;  Q3IJC9, HUTI_PSEHT ;  A4XZQ4, HUTI_PSEMY ;
DR   A5WA64, HUTI_PSEP1 ;  Q3KJE5, HUTI_PSEPF ;  B0KM55, HUTI_PSEPG ;
DR   Q88CZ9, HUTI_PSEPK ;  O31200, HUTI_PSEPU ;  Q87UL9, HUTI_PSESM ;
DR   Q4ZLW0, HUTI_PSEU2 ;  Q1Q9E2, HUTI_PSYCK ;  A1STQ6, HUTI_PSYIN ;
DR   A4WKX3, HUTI_PYRAR ;  Q1LJF1, HUTI_RALME ;  Q8XW31, HUTI_RALSO ;
DR   Q983I1, HUTI_RHILO ;  O31196, HUTI_RHIME ;  Q2RUU1, HUTI_RHORT ;
DR   A3PK22, HUTI_RHOS1 ;  Q3J290, HUTI_RHOS4 ;  B9KSW5, HUTI_RHOSK ;
DR   Q0S7Q9, HUTI_RHOSR ;  Q162E3, HUTI_ROSDO ;  Q1AYH1, HUTI_RUBXD ;
DR   A4FNE8, HUTI_SACEN ;  B5F065, HUTI_SALA4 ;  A8M4I4, HUTI_SALAI ;
DR   A9MJF3, HUTI_SALAR ;  Q57RH0, HUTI_SALCH ;  B5FP54, HUTI_SALDC ;
DR   B5QX58, HUTI_SALEP ;  B5R754, HUTI_SALG2 ;  B4TC41, HUTI_SALHS ;
DR   Q5PG58, HUTI_SALPA ;  A9MTJ5, HUTI_SALPB ;  C0PWX5, HUTI_SALPC ;
DR   B5BC37, HUTI_SALPK ;  B4TQT2, HUTI_SALSV ;  Q8Z8A0, HUTI_SALTI ;
DR   A4X3X8, HUTI_SALTO ;  Q8ZQR2, HUTI_SALTY ;  A8GDJ0, HUTI_SERP5 ;
DR   A1S1N6, HUTI_SHEAM ;  B8E3L5, HUTI_SHEB2 ;  A3DAF6, HUTI_SHEB5 ;
DR   A6WHH8, HUTI_SHEB8 ;  A9KV78, HUTI_SHEB9 ;  Q12T48, HUTI_SHEDO ;
DR   Q07W34, HUTI_SHEFN ;  B0TM54, HUTI_SHEHH ;  A3QJH7, HUTI_SHELP ;
DR   Q8EKJ7, HUTI_SHEON ;  A8HA94, HUTI_SHEPA ;  A4Y1I0, HUTI_SHEPC ;
DR   B8CGY2, HUTI_SHEPW ;  A0KRC4, HUTI_SHESA ;  A8G1S8, HUTI_SHESH ;
DR   Q0HP39, HUTI_SHESM ;  Q0I0K7, HUTI_SHESR ;  A1RQ59, HUTI_SHESW ;
DR   B1KP58, HUTI_SHEWM ;  Q5LRD9, HUTI_SILPO ;  Q1GC80, HUTI_SILST ;
DR   Q01W05, HUTI_SOLUE ;  Q1GSH1, HUTI_SPHAL ;  A5VFA5, HUTI_SPHWW ;
DR   A7X5T3, HUTI_STAA1 ;  A6U455, HUTI_STAA2 ;  Q2FEG6, HUTI_STAA3 ;
DR   Q2FVT6, HUTI_STAA8 ;  A5IVB2, HUTI_STAA9 ;  Q2YYV8, HUTI_STAAB ;
DR   Q5HDM7, HUTI_STAAC ;  A6QJH1, HUTI_STAAE ;  P64417, HUTI_STAAM ;
DR   P64418, HUTI_STAAN ;  Q6GEA5, HUTI_STAAR ;  Q6G6Z0, HUTI_STAAS ;
DR   A8Z519, HUTI_STAAT ;  Q8NV65, HUTI_STAAW ;  Q49ZQ6, HUTI_STAS1 ;
DR   Q82HL5, HUTI_STRAW ;  Q9KZ78, HUTI_STRCO ;  A8AZ63, HUTI_STRGC ;
DR   B1VUR8, HUTI_STRGG ;  P42358, HUTI_STRGN ;  B4SP54, HUTI_STRM5 ;
DR   P58080, HUTI_STRP1 ;  P0DB76, HUTI_STRP3 ;  Q5X9L1, HUTI_STRP6 ;
DR   Q8NZ53, HUTI_STRP8 ;  Q1J9F6, HUTI_STRPB ;  Q1JJK6, HUTI_STRPC ;
DR   Q1JEK8, HUTI_STRPD ;  Q1J4C4, HUTI_STRPF ;  A2RGR8, HUTI_STRPG ;
DR   Q48QZ6, HUTI_STRPM ;  P0DB77, HUTI_STRPQ ;  B5XIX5, HUTI_STRPZ ;
DR   A3CL31, HUTI_STRSV ;  Q67JH7, HUTI_SYMTH ;  A0LKV6, HUTI_SYNFM ;
DR   Q9HLJ0, HUTI_THEAC ;  B0KCB7, HUTI_THEP3 ;  Q8RCH7, HUTI_THETN ;
DR   Q978N3, HUTI_THEVO ;  Q73RN8, HUTI_TREDE ;  A1WP07, HUTI_VEREI ;
DR   A5F1X8, HUTI_VIBC3 ;  Q9KSQ1, HUTI_VIBCH ;  C3LLQ1, HUTI_VIBCM ;
DR   Q5E0C3, HUTI_VIBF1 ;  B5ETN4, HUTI_VIBFM ;  A7MVK3, HUTI_VIBHB ;
DR   Q87Q74, HUTI_VIBPA ;  Q8DA18, HUTI_VIBVU ;  Q7MK61, HUTI_VIBVY ;
DR   Q8PLZ7, HUTI_XANAC ;  Q3BV03, HUTI_XANC5 ;  Q4UTC0, HUTI_XANC8 ;
DR   Q8PAA6, HUTI_XANCP ;  Q2P345, HUTI_XANOM ;  B2SJI1, HUTI_XANOP ;
DR   Q5H071, HUTI_XANOR ;  Q561L6, HUTI_XENLA ;  Q68EP2, HUTI_XENTR ;
DR   A1JS25, HUTI_YERE8 ;  A7FIK8, HUTI_YERP3 ;  Q1C8A1, HUTI_YERPA ;
DR   Q9ZC74, HUTI_YERPE ;  A9QZ55, HUTI_YERPG ;  Q1CJP8, HUTI_YERPN ;
DR   A4TJT7, HUTI_YERPP ;  Q66B14, HUTI_YERPS ;  B1JMC6, HUTI_YERPY ;
//
ID   3.5.2.8
DE   Transferred entry: 3.5.2.6.
//
ID   3.5.2.9
DE   5-oxoprolinase (ATP-hydrolyzing).
AN   5-OPase.
AN   5-oxo-L-prolinase.
AN   Pyroglutamase (ATP-hydrolyzing).
CA   ATP + 5-oxo-L-proline + 2 H(2)O = ADP + phosphate + L-glutamate.
DR   Q9FIZ7, OPLA_ARATH ;  Q75WB5, OPLA_BOVIN ;  Q54NW6, OPLA_DICDI ;
DR   O14841, OPLA_HUMAN ;  Q8K010, OPLA_MOUSE ;  P97608, OPLA_RAT   ;
DR   P28273, OPLA_YEAST ;
//
ID   3.5.2.10
DE   Creatininase.
AN   Creatinine amidohydrolase.
CA   Creatinine + H(2)O = creatine.
DR   P83772, CRNA_PSEPU ;
//
ID   3.5.2.11
DE   L-lysine-lactamase.
AN   L-alpha-aminocaprolactam hydrolase.
AN   L-lysinamidase.
CA   L-lysine 1,6-lactam + H(2)O = L-lysine.
CC   -!- Also hydrolyzes L-lysinamide.
//
ID   3.5.2.12
DE   6-aminohexanoate-cyclic-dimer hydrolase.
CA   1,8-diazacyclotetradecane-2,9-dione + H(2)O = N-(6-aminohexanoyl)-6-
CA   aminohexanoate.
CC   -!- The cyclic dimer of 6-aminohexanoate is converted to the linear
CC       dimer.
PR   PROSITE; PDOC00494;
DR   P13398, NYLA_FLASK ;  P13397, NYLA_PSES8 ;
//
ID   3.5.2.13
DE   2,5-dioxopiperazine hydrolase.
AN   Cyclo(Gly-Gly) hydrolase.
CA   2,5-dioxopiperazine + H(2)O = glycylglycine.
CC   -!- Highly specific; does not hydrolyze other dioxopiperazines,
CC       glycylglycine, proteins or barbiturates.
//
ID   3.5.2.14
DE   N-methylhydantoinase (ATP-hydrolyzing).
AN   N-methylhydantoin amidohydrolase.
CA   ATP + N-methylimidazolidine-2,4-dione + 2 H(2)O = ADP + phosphate +
CA   N-carbamoylsarcosine.
//
ID   3.5.2.15
DE   Cyanuric acid amidohydrolase.
CA   Cyanuric acid + H(2)O = biuret + CO(2).
CC   -!- Along with EC 3.5.1.54 and EC 3.5.1.84, forms part of the cyanuric-
CC       acid metabolism pathway, which degrades s-triazide herbicides, such
CC       as atrazine (2-chloro-4-(ethylamino)-6-(isopropylamino)-1,3,5-
CC       triazine), in bacteria.
CC   -!- A key enzyme in the pathway, catalyzing the ring cleavage of cyanuric
CC       acid.
CC   -!- Specific for cyanuric acid as substrate as neither the structurally
CC       related compounds ammeline (2,4-diamino-6-hydroxy-s-triazine) and
CC       ammelide (2-amino-4,6-dihydroxy-s-triazine) nor a number of
CC       pyrimidine compounds, such as uracil and cytosine, can act as
CC       substrates.
DR   P58329, ATZD_PSESD ;  P0A3V4, TRZD_ENTCL ;  P0A3V5, TRZD_PSESP ;
//
ID   3.5.2.16
DE   Maleimide hydrolase.
AN   Cyclic imide hydrolase.
AN   Imidase.
CA   Maleimide + H(2)O = maleamic acid.
CC   -!- Succinimide and glutarimide, and sulfur-containing cyclic imides,
CC       such as rhodanine, can also act as substrates for the enzyme from
CC       Blastobacter sp. A17p-4.
CC   -!- The reverse, cyclization, reaction is also catalyzed, but much more
CC       slowly.
CC   -!- It has lower activity toward cyclic ureides, which are the substrates
CC       of EC 3.5.2.2.
//
ID   3.5.2.17
DE   Hydroxyisourate hydrolase.
AN   5-hydroxyisourate hydrolase.
AN   HIUHase.
CA   5-hydroxyisourate + H(2)O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-
CA   1H-imidazole-5-carboxylate.
CC   -!- The reaction is the first stage in the conversion of
CC       5-hydroxyisourate into (S)-allantoin.
CC   -!- This reaction will also occur spontaneously, but more slowly.
DR   Q21882, HIUH1_CAEEL;  Q92VB9, HIUH1_RHIME;  O44578, HIUH2_CAEEL;
DR   Q92UG5, HIUH2_RHIME;  Q9KET9, HIUH_BACHD ;  O32142, HIUH_BACSU ;
DR   Q8YFU1, HIUH_BRUME ;  Q8G228, HIUH_BRUSU ;  Q9A545, HIUH_CAUCR ;
DR   Q06S87, HIUH_DANRE ;  Q9RV69, HIUH_DEIRA ;  Q8XB75, HIUH_ECO57 ;
DR   P76341, HIUH_ECOLI ;  Q9CRB3, HIUH_MOUSE ;  Q9I3J5, HIUH_PSEAE ;
DR   Q8XXJ7, HIUH_RALSO ;  Q98CI7, HIUH_RHILO ;  Q4VYA5, HIUH_SALDU ;
DR   Q8Z7Q6, HIUH_SALTI ;  Q8ZQ52, HIUH_SALTY ;  O74492, HIUH_SCHPO ;
DR   Q8S3J3, HIUH_SOYBN ;  Q9LVM5, TTHL_ARATH ;
//
ID   3.5.2.18
DE   Enamidase.
CA   6-oxo-1,4,5,6-tetrahydronicotinate + 2 H(2)O = 2-formylglutarate + NH(3).
CF   Iron; Zinc.
CC   -!- Forms part of the nicotinate-fermentation catabolism pathway in
CC       Eubacterium barkeri.
CC   -!- Other enzymes involved in this pathway are EC 1.17.1.5, EC 1.3.7.1,
CC       EC 1.1.1.291, EC 5.4.99.4, EC 5.3.3.6, EC 4.2.1.85 and EC 4.1.3.32.
DR   Q0QLE9, ENA_EUBBA  ;
//
ID   3.5.2.19
DE   Streptothricin hydrolase.
CA   Streptothricin-F + H(2)O = streptothricin-F acid.
CC   -!- The enzyme also catalyzes the hydrolysis of streptothricin-D to
CC       streptothricin-D acid.
CC   -!- The enzyme is responsible for streptothricin resistance in
CC       Streptomyces albulus and Streptomyces noursei.
//
ID   3.5.3.1
DE   Arginase.
AN   Arginine amidinase.
AN   Canavanase.
CA   L-arginine + H(2)O = L-ornithine + urea.
CF   Manganese.
CC   -!- Also hydrolyzes alpha-N-substituted L-arginines and canavanine.
PR   PROSITE; PDOC00135;
DR   P46637, ARGI1_ARATH;  Q2KJ64, ARGI1_BOVIN;  P05089, ARGI1_HUMAN;
DR   Q61176, ARGI1_MOUSE;  Q95JC8, ARGI1_PIG  ;  Q95KM0, ARGI1_RABIT;
DR   P07824, ARGI1_RAT  ;  P37818, ARGI1_SCHPO;  P30759, ARGI1_XENLA;
DR   Q9ZPF5, ARGI2_ARATH;  Q58DL1, ARGI2_BOVIN;  P78540, ARGI2_HUMAN;
DR   O08691, ARGI2_MOUSE;  Q4VK78, ARGI2_RABIT;  O08701, ARGI2_RAT  ;
DR   Q10066, ARGI2_SCHPO;  P14012, ARGI_AGRT5 ;  Q74ZW4, ARGI_ASHGO ;
DR   P53608, ARGI_BACCD ;  P39138, ARGI_BACSU ;  Q7M0Z3, ARGI_BREBE ;
DR   P0A2Y1, ARGI_BRUAB ;  P0A2X9, ARGI_BRUME ;  P0A2Y0, ARGI_BRUSU ;
DR   Q1E180, ARGI_COCIM ;  P40906, ARGI_COCP7 ;  Q12611, ARGI_EMENI ;
DR   P33280, ARGI_NEUCR ;  P49900, ARGI_RANCA ;  O49046, ARGI_SOYBN ;
DR   P60086, ARGI_STAAC ;  P60087, ARGI_STAAM ;  P60088, ARGI_STAAN ;
DR   Q6GER3, ARGI_STAAR ;  Q6G7E9, ARGI_STAAS ;  Q8NVE3, ARGI_STAAW ;
DR   P00812, ARGI_YEAST ;  Q91553, ARGN1_XENLA;  Q91554, ARGN2_XENLA;
DR   Q91555, ARGN3_XENLA;
//
ID   3.5.3.2
DE   Guanidinoacetase.
AN   Glycocyaminase.
CA   Guanidinoacetate + H(2)O = glycine + urea.
CF   Manganese.
//
ID   3.5.3.3
DE   Creatinase.
AN   Creatine amidinohydrolase.
CA   Creatine + H(2)O = sarcosine + urea.
DR   P38487, CREA_BACB0 ;  P19213, CREA_FLASU ;  P38488, CREA_PSEPU ;
//
ID   3.5.3.4
DE   Allantoicase.
AN   Allantoate amidinohydrolase.
CA   Allantoate + H(2)O = (S)-ureidoglycolate + urea.
CC   -!- Also hydrolyzes (R)-ureidoglycolate to glyoxylate and urea.
DR   Q62JH0, ALLC1_BURMA;  Q63T53, ALLC1_BURPS;  Q62H14, ALLC2_BURMA;
DR   Q63QS9, ALLC2_BURPS;  Q6F6Y1, ALLC_ACIAD ;  B7GV54, ALLC_ACIB3 ;
DR   B7ICG5, ALLC_ACIB5 ;  B2I1L5, ALLC_ACIBC ;  B0VP26, ALLC_ACIBS ;
DR   A3MA02, ALLC_ACIBT ;  B0V9T8, ALLC_ACIBY ;  Q2KIG4, ALLC_BOVIN ;
DR   P82678, ALLC_CHLRE ;  Q6DGA6, ALLC_DANRE ;  Q54VL5, ALLC_DICDI ;
DR   Q8N6M5, ALLC_HUMAN ;  Q4R964, ALLC_MACFA ;  Q9JHX6, ALLC_MOUSE ;
DR   P18407, ALLC_NEUCR ;  Q5YP02, ALLC_NOCFA ;  Q6LPX9, ALLC_PHOPR ;
DR   Q48KS4, ALLC_PSE14 ;  A6V7Y9, ALLC_PSEA7 ;  B7UW33, ALLC_PSEA8 ;
DR   Q02JZ8, ALLC_PSEAB ;  Q9I3J8, ALLC_PSEAE ;  Q4K8H3, ALLC_PSEF5 ;
DR   C3K0A7, ALLC_PSEFS ;  Q3KFK9, ALLC_PSEPF ;  Q87YX4, ALLC_PSESM ;
DR   Q4ZVG8, ALLC_PSEU2 ;  A4VP32, ALLC_PSEU5 ;  B2UG65, ALLC_RALPJ ;
DR   Q8XUB7, ALLC_RALSO ;  Q6AYP0, ALLC_RAT   ;  Q92VC1, ALLC_RHIME ;
DR   Q09913, ALLC_SCHPO ;  Q82LL5, ALLC_STRAW ;  Q9RKU4, ALLC_STRCO ;
DR   Q9W6S5, ALLC_XENLA ;  Q640T1, ALLC_XENTR ;  P25335, ALLC_YEAST ;
//
ID   3.5.3.5
DE   Formimidoylaspartate deiminase.
AN   Formiminoaspartate deiminase.
CA   N-formimidoyl-L-aspartate + H(2)O = N-formyl-L-aspartate + NH(3).
//
ID   3.5.3.6
DE   Arginine deiminase.
AN   Arginine dihydrolase.
CA   L-arginine + H(2)O = L-citrulline + NH(3).
CC   -!- Also acts on canavanine.
DR   Q92ZT2, ARCA1_RHIME;  Q8CQG5, ARCA1_STAES;  Q8FAD9, ARCA2_ECOL6;
DR   Q92YG5, ARCA2_RHIME;  Q8CMW1, ARCA2_STAES;  B6EMS7, ARCA_ALISL ;
DR   A0R969, ARCA_BACAH ;  B7JN59, ARCA_BACC0 ;  Q73E87, ARCA_BACC1 ;
DR   B7IV32, ARCA_BACC2 ;  B7H7F6, ARCA_BACC4 ;  A7GKP8, ARCA_BACCN ;
DR   Q81II1, ARCA_BACCR ;  Q6HP29, ARCA_BACHK ;  O86131, ARCA_BACLD ;
DR   O51896, ARCA_BORAF ;  Q0SM08, ARCA_BORAP ;  O51781, ARCA_BORBU ;
DR   B7J0T5, ARCA_BORBZ ;  B5RN40, ARCA_BORDL ;  Q65ZT1, ARCA_BORGA ;
DR   B5RQH8, ARCA_BORRA ;  A1R0R8, ARCA_BORT9 ;  Q89DX7, ARCA_BRAJA ;
DR   Q62KD9, ARCA_BURMA ;  Q63U73, ARCA_BURPS ;  Q7NRJ9, ARCA_CHRVO ;
DR   Q0TUR5, ARCA_CLOP1 ;  P0C2E1, ARCA_CLOPE ;  Q0SWK6, ARCA_CLOPS ;
DR   C3PEE7, ARCA_CORA7 ;  A5EXR1, ARCA_DICNV ;  A8LN36, ARCA_DINSH ;
DR   B7NUG6, ARCA_ECO7I ;  B7MSY5, ARCA_ECO81 ;  A1AJF5, ARCA_ECOK1 ;
DR   Q93K67, ARCA_ENTFA ;  B7LMS3, ARCA_ESCF3 ;  Q2SB21, ARCA_HAHCH ;
DR   B8D2J5, ARCA_HALOH ;  Q03NY8, ARCA_LACBA ;  B2GAF4, ARCA_LACF3 ;
DR   Q8G999, ARCA_LACHI ;  P58013, ARCA_LACLA ;  Q9K576, ARCA_LACLM ;
DR   A5VIN9, ARCA_LACRD ;  B2G669, ARCA_LACRJ ;  O53088, ARCA_LACSK ;
DR   Q38YQ6, ARCA_LACSS ;  Q92FR7, ARCA_LISIN ;  C1KV84, ARCA_LISMC ;
DR   Q725C1, ARCA_LISMF ;  B8DAM3, ARCA_LISMH ;  Q8YAS0, ARCA_LISMO ;
DR   A0AEM0, ARCA_LISW6 ;  A6VWS0, ARCA_MARMS ;  Q11G43, ARCA_MESSB ;
DR   A0QBT9, ARCA_MYCA1 ;  B3PNI8, ARCA_MYCA5 ;  P23793, ARCA_MYCAR ;
DR   P63552, ARCA_MYCBO ;  A1KHD9, ARCA_MYCBP ;  C1ALZ2, ARCA_MYCBT ;
DR   Q2ST29, ARCA_MYCCT ;  A4T6Q0, ARCA_MYCGI ;  P41141, ARCA_MYCHO ;
DR   B2HDL4, ARCA_MYCMM ;  P75475, ARCA_MYCPN ;  A5U144, ARCA_MYCTA ;
DR   P63551, ARCA_MYCTU ;  A0PW79, ARCA_MYCUA ;  Q04EV5, ARCA_OENOB ;
DR   Q03DS2, ARCA_PEDPA ;  Q6AA78, ARCA_PROAC ;  P13981, ARCA_PSEAE ;
DR   A4XRA9, ARCA_PSEMY ;  Q88P52, ARCA_PSEPK ;  P41142, ARCA_PSEPU ;
DR   B3PWQ6, ARCA_RHIE6 ;  O31017, ARCA_RHIET ;  Q988I1, ARCA_RHILO ;
DR   C1A399, ARCA_RHOE4 ;  C1AXW8, ARCA_RHOOB ;  Q0S4V3, ARCA_RHOSR ;
DR   A9MEV5, ARCA_SALAR ;  Q57GD5, ARCA_SALCH ;  C0Q7C5, ARCA_SALPC ;
DR   Q8Z125, ARCA_SALTI ;  Q8ZK33, ARCA_SALTY ;  A7X719, ARCA_STAA1 ;
DR   A6U519, ARCA_STAA2 ;  Q2FUX7, ARCA_STAA8 ;  A5IW62, ARCA_STAA9 ;
DR   Q2YZ66, ARCA_STAAB ;  Q5HCR2, ARCA_STAAC ;  A6QKC4, ARCA_STAAE ;
DR   P63553, ARCA_STAAM ;  P63554, ARCA_STAAN ;  Q6GDG7, ARCA_STAAR ;
DR   Q6G639, ARCA_STAAS ;  Q8NUK7, ARCA_STAAW ;  Q5HKU2, ARCA_STAEQ ;
DR   Q4L9J9, ARCA_STAHJ ;  Q3JYE2, ARCA_STRA1 ;  Q8E2K0, ARCA_STRA3 ;
DR   Q8DWQ2, ARCA_STRA5 ;  Q9RJN1, ARCA_STRCO ;  C0MBK4, ARCA_STRE4 ;
DR   B4U1S0, ARCA_STREM ;  A8AYL1, ARCA_STRGC ;  P0C0B4, ARCA_STRP1 ;
DR   P0CZ64, ARCA_STRP3 ;  B5E3F7, ARCA_STRP4 ;  Q5XAY2, ARCA_STRP6 ;
DR   C1CAZ3, ARCA_STRP7 ;  P68770, ARCA_STRP8 ;  Q1JAR2, ARCA_STRPB ;
DR   Q1JKW3, ARCA_STRPC ;  Q1JFY9, ARCA_STRPD ;  Q1J5Q4, ARCA_STRPF ;
DR   P58827, ARCA_STRPG ;  B1I9W0, ARCA_STRPI ;  B8ZPY7, ARCA_STRPJ ;
DR   Q48SI7, ARCA_STRPM ;  Q97NA4, ARCA_STRPN ;  P0CZ65, ARCA_STRPQ ;
DR   B2ING9, ARCA_STRPS ;  P0C0B3, ARCA_STRPY ;  B5XMC3, ARCA_STRPZ ;
DR   C0MD79, ARCA_STRS7 ;  A3CLW6, ARCA_STRSV ;  B9DUZ0, ARCA_STRU0 ;
DR   C1CHE6, ARCA_STRZJ ;  C1CNC2, ARCA_STRZP ;  C1CU66, ARCA_STRZT ;
DR   C4LA78, ARCA_TOLAT ;  Q73QJ2, ARCA_TREDE ;  A5F8P7, ARCA_VIBC3 ;
DR   Q9KUU2, ARCA_VIBCH ;  C3LRF4, ARCA_VIBCM ;  Q5E7U3, ARCA_VIBF1 ;
DR   B5F9Q1, ARCA_VIBFM ;  A7MSD7, ARCA_VIBHB ;  Q87LG0, ARCA_VIBPA ;
DR   Q8DCF4, ARCA_VIBVU ;  Q7MHF3, ARCA_VIBVY ;
//
ID   3.5.3.7
DE   Guanidinobutyrase.
CA   4-guanidinobutanoate + H(2)O = 4-aminobutanoate + urea.
CF   Manganese.
CC   -!- Also acts, very slowly, on 5-guanidinopentanoate and 6-guanidino-
CC       hexanoate.
PR   PROSITE; PDOC00135;
DR   Q8KZT5, GBH_ARTS8  ;
//
ID   3.5.3.8
DE   Formimidoylglutamase.
AN   Formiminoglutamase.
AN   Formiminoglutamate hydrolase.
CA   N-formimidoyl-L-glutamate + H(2)O = L-glutamate + formamide.
PR   PROSITE; PDOC00135;
DR   A0KF85, HUTG_AERHH ;  A4SSN4, HUTG_AERS4 ;  Q5NZY1, HUTG_AROAE ;
DR   Q9KBE3, HUTG_BACHD ;  P42068, HUTG_BACSU ;  Q7WJ55, HUTG_BORBR ;
DR   B2TFB8, HUTG_BURPP ;  Q13PQ0, HUTG_BURXL ;  P60109, HUTG_CHRVO ;
DR   A8AJ18, HUTG_CITK8 ;  Q893K6, HUTG_CLOTE ;  Q8FQ76, HUTG_COREF ;
DR   Q0KFM5, HUTG_CUPNH ;  Q471H6, HUTG_CUPPJ ;  A4W8B2, HUTG_ENT38 ;
DR   P19452, HUTG_ENTAE ;  Q8RFN0, HUTG_FUSNN ;  Q5L086, HUTG_GEOKA ;
DR   C5DA16, HUTG_GEOSW ;  A4IMP1, HUTG_GEOTN ;  Q2SEP7, HUTG_HAHCH ;
DR   B0R542, HUTG_HALS3 ;  Q9HQD7, HUTG_HALSA ;  B5XZ82, HUTG_KLEP3 ;
DR   A6T6K8, HUTG_KLEP7 ;  Q5X741, HUTG_LEGPA ;  Q5ZXM2, HUTG_LEGPH ;
DR   Q5WYJ0, HUTG_LEGPL ;  B1HQK2, HUTG_LYSSC ;  B9E7J8, HUTG_MACCJ ;
DR   Q5Z0G1, HUTG_NOCFA ;  P60110, HUTG_PHOLL ;  Q6LQ58, HUTG_PHOPR ;
DR   A6V2Q0, HUTG_PSEA7 ;  B7V9J1, HUTG_PSEA8 ;  Q02PY1, HUTG_PSEAB ;
DR   Q9HZ59, HUTG_PSEAE ;  Q4KJT9, HUTG_PSEF5 ;  Q1Q9E3, HUTG_PSYCK ;
DR   Q8XW30, HUTG_RALSO ;  C1BBD1, HUTG_RHOOB ;  Q0S7R0, HUTG_RHOSR ;
DR   B5F066, HUTG_SALA4 ;  A9MJF2, HUTG_SALAR ;  Q57RG9, HUTG_SALCH ;
DR   B5FP55, HUTG_SALDC ;  B5QX59, HUTG_SALEP ;  B5R755, HUTG_SALG2 ;
DR   B4TC42, HUTG_SALHS ;  B4SZJ1, HUTG_SALNS ;  Q5PG59, HUTG_SALPA ;
DR   A9MTJ4, HUTG_SALPB ;  C0PWX6, HUTG_SALPC ;  B5BC36, HUTG_SALPK ;
DR   B4TQT3, HUTG_SALSV ;  Q8Z899, HUTG_SALTI ;  Q8ZQR1, HUTG_SALTY ;
DR   A7X5U0, HUTG_STAA1 ;  A6U459, HUTG_STAA2 ;  Q2FEG2, HUTG_STAA3 ;
DR   Q2FVT2, HUTG_STAA8 ;  A5IVB6, HUTG_STAA9 ;  Q2YYV4, HUTG_STAAB ;
DR   Q5HDM3, HUTG_STAAC ;  A6QJH5, HUTG_STAAE ;  P63570, HUTG_STAAM ;
DR   P99158, HUTG_STAAN ;  Q6GEA1, HUTG_STAAR ;  Q6G6Y7, HUTG_STAAS ;
DR   A8Z523, HUTG_STAAT ;  Q8NV63, HUTG_STAAW ;  B9DLS6, HUTG_STACT ;
DR   Q5HLR4, HUTG_STAEQ ;  Q8CNA3, HUTG_STAES ;  Q4L8J3, HUTG_STAHJ ;
DR   A8AZ72, HUTG_STRGC ;  Q99XQ9, HUTG_STRP1 ;  P0CZ66, HUTG_STRP3 ;
DR   Q5X9K2, HUTG_STRP6 ;  Q8NZ45, HUTG_STRP8 ;  Q1J9E8, HUTG_STRPB ;
DR   Q1JJJ7, HUTG_STRPC ;  Q1JEK0, HUTG_STRPD ;  Q1J4B6, HUTG_STRPF ;
DR   A2RGS6, HUTG_STRPG ;  Q48QY8, HUTG_STRPM ;  P0CZ67, HUTG_STRPQ ;
DR   B5XIY3, HUTG_STRPZ ;  A5F1X7, HUTG_VIBC3 ;  Q9KSQ2, HUTG_VIBCH ;
DR   C3LLQ0, HUTG_VIBCM ;  Q5E0C4, HUTG_VIBF1 ;  Q87Q75, HUTG_VIBPA ;
DR   Q8DA19, HUTG_VIBVU ;  P60111, HUTG_VIBVY ;
//
ID   3.5.3.9
DE   Allantoate deiminase.
CA   Allantoate + H(2)O = (S)-ureidoglycine + NH(3) + CO(2).
CF   Manganese.
CC   -!- This enzyme is part of the ureide pathway, which permits certain
CC       organisms to recycle the nitrogen in purine compounds.
CC   -!- This enzyme, which liberates ammonia from allantoate, is present in
CC       plants and bacteria.
CC   -!- In plants it is localized in the endoplasmic reticulum.
CC   -!- Requires manganese.
DR   O49434, AAH_ARATH  ;
//
ID   3.5.3.10
DE   D-arginase.
CA   D-arginine + H(2)O = D-ornithine + urea.
DR   Q8KZT5, GBH_ARTS8  ;
//
ID   3.5.3.11
DE   Agmatinase.
AN   Agmatine ureohydrolase.
CA   Agmatine + H(2)O = putrescine + urea.
PR   PROSITE; PDOC00135;
DR   Q10088, SPEB1_SCHPO;  P72703, SPEB1_SYNY3;  O42887, SPEB2_SCHPO;
DR   P73270, SPEB2_SYNY3;  Q9C0Y9, SPEB3_SCHPO;  Q81JT1, SPEB_BACAN ;
DR   Q814Q2, SPEB_BACCR ;  Q9K6B9, SPEB_BACHD ;  P70999, SPEB_BACSU ;
DR   Q7VRG4, SPEB_BLOFL ;  Q90XD2, SPEB_CHICK ;  Q7P0S6, SPEB_CHRVO ;
DR   A8APF8, SPEB_CITK8 ;  A7ZR59, SPEB_ECO24 ;  B7UHY3, SPEB_ECO27 ;
DR   B7MMC5, SPEB_ECO45 ;  B7LFJ6, SPEB_ECO55 ;  P60652, SPEB_ECO57 ;
DR   B5YQD4, SPEB_ECO5E ;  B7NI01, SPEB_ECO7I ;  B7MZN5, SPEB_ECO81 ;
DR   B7LYW6, SPEB_ECO8A ;  C5A0K6, SPEB_ECOBW ;  B1XF99, SPEB_ECODH ;
DR   A8A477, SPEB_ECOHS ;  A1AFC5, SPEB_ECOK1 ;  Q0TDR4, SPEB_ECOL5 ;
DR   Q8FE36, SPEB_ECOL6 ;  B1IT67, SPEB_ECOLC ;  P60651, SPEB_ECOLI ;
DR   B7N7I9, SPEB_ECOLU ;  B6I775, SPEB_ECOSE ;  B1LDE6, SPEB_ECOSM ;
DR   Q1R791, SPEB_ECOUT ;  C5BAV1, SPEB_EDWI9 ;  A4WE75, SPEB_ENT38 ;
DR   A7MJQ1, SPEB_ENTS8 ;  B7LPE7, SPEB_ESCF3 ;  Q9BSE5, SPEB_HUMAN ;
DR   B5XUB2, SPEB_KLEP3 ;  A6TDU9, SPEB_KLEP7 ;  A2AS89, SPEB_MOUSE ;
DR   Q5F6R3, SPEB_NEIG1 ;  B4RP98, SPEB_NEIG2 ;  A9M254, SPEB_NEIM0 ;
DR   P60653, SPEB_NEIMA ;  P60654, SPEB_NEIMB ;  A1KVF9, SPEB_NEIMF ;
DR   Q7N122, SPEB_PHOLL ;  B4F1A3, SPEB_PROMH ;  Q7X3P1, SPEB_PROMI ;
DR   Q0D2L3, SPEB_RAT   ;  B5F5K3, SPEB_SALA4 ;  Q57K36, SPEB_SALCH ;
DR   B5FUJ0, SPEB_SALDC ;  B5QXK5, SPEB_SALEP ;  B5RE39, SPEB_SALG2 ;
DR   B4THG3, SPEB_SALHS ;  B4T5I5, SPEB_SALNS ;  Q5PJH7, SPEB_SALPA ;
DR   A9N3R6, SPEB_SALPB ;  C0PY54, SPEB_SALPC ;  B5BFP3, SPEB_SALPK ;
DR   B4TV53, SPEB_SALSV ;  P60655, SPEB_SALTI ;  P60656, SPEB_SALTY ;
DR   A8GIX7, SPEB_SERP5 ;  B2U0V8, SPEB_SHIB3 ;  Q31WK0, SPEB_SHIBS ;
DR   Q32C02, SPEB_SHIDS ;  Q0T0V7, SPEB_SHIF8 ;  P60657, SPEB_SHIFL ;
DR   Q3YXT4, SPEB_SHISS ;  Q2NRD3, SPEB_SODGM ;
//
ID   3.5.3.12
DE   Agmatine deiminase.
CA   Agmatine + H(2)O = N-carbamoylputrescine + NH(3).
CC   -!- The plant enzyme also catalyzes the reactions of EC 2.1.3.3,
CC       EC 2.1.3.6 and EC 2.7.2.2, thus functioning as a putrescine synthase,
CC       converting agmatine and ornithine into putrescine and citrulline,
CC       respectively.
DR   Q725C6, AGUA1_LISMF;  Q8YAS5, AGUA1_LISMO;  Q725C4, AGUA2_LISMF;
DR   Q8YAS3, AGUA2_LISMO;  Q8GWW7, AGUA_ARATH ;  Q837U5, AGUA_ENTFA ;
DR   Q6CZ80, AGUA_ERWCT ;  Q9CEY6, AGUA_LACLA ;  Q8RPX2, AGUA_LACSS ;
DR   Q5X986, AGUA_LEGPA ;  Q5ZZK4, AGUA_LEGPH ;  Q5X0L4, AGUA_LEGPL ;
DR   A6VVD9, AGUA_MARMS ;  Q2SRJ6, AGUA_MYCCT ;  Q6MSR8, AGUA_MYCMS ;
DR   Q6LG16, AGUA_PHOPR ;  Q48Q55, AGUA_PSE14 ;  A6UY93, AGUA_PSEA7 ;
DR   B7V2K4, AGUA_PSEA8 ;  Q02UC5, AGUA_PSEAB ;  Q9I6J9, AGUA_PSEAE ;
DR   Q4KJX9, AGUA_PSEF5 ;  C3K5U8, AGUA_PSEFS ;  A4XP44, AGUA_PSEMY ;
DR   A5VX45, AGUA_PSEP1 ;  B0KI18, AGUA_PSEPG ;  Q88R68, AGUA_PSEPK ;
DR   Q87UB2, AGUA_PSESM ;  Q4ZLL3, AGUA_PSEU2 ;  A4VFL7, AGUA_PSEU5 ;
DR   Q5KR05, AGUA_SELRU ;  B8E8S8, AGUA_SHEB2 ;  A3D798, AGUA_SHEB5 ;
DR   A6WR31, AGUA_SHEB8 ;  A9KYH3, AGUA_SHEB9 ;  Q083U9, AGUA_SHEFN ;
DR   Q8EIF2, AGUA_SHEON ;  A4Y946, AGUA_SHEPC ;  A0L0W9, AGUA_SHESA ;
DR   Q0HF12, AGUA_SHESM ;  Q0HYZ3, AGUA_SHESR ;  A1RHF0, AGUA_SHESW ;
DR   Q82JP0, AGUA_STRAW ;  O86509, AGUA_STRCO ;  Q8DW17, AGUA_STRMU ;
DR   Q04L01, AGUA_STRP2 ;  C1C6Q3, AGUA_STRP7 ;  B1IB89, AGUA_STRPI ;
DR   B8ZP26, AGUA_STRPJ ;  Q97RA4, AGUA_STRPN ;  B2IP79, AGUA_STRPS ;
DR   Q8DQ68, AGUA_STRR6 ;  C1CDR9, AGUA_STRZJ ;  C1CK08, AGUA_STRZP ;
DR   C1CRX2, AGUA_STRZT ;  Q87NU5, AGUA_VIBPA ;  A7FEY8, AGUA_YERP3 ;
DR   Q8ZHG0, AGUA_YERPE ;  Q666N7, AGUA_YERPS ;
//
ID   3.5.3.13
DE   Formimidoylglutamate deiminase.
AN   Formiminoglutamate deiminase.
CA   N-formimidoyl-L-glutamate + H(2)O = N-formyl-L-glutamate + NH(3).
//
ID   3.5.3.14
DE   Amidinoaspartase.
CA   N-amidino-L-aspartate + H(2)O = L-aspartate + urea.
CC   -!- Also acts slowly on N-amidino-L-glutamate.
//
ID   3.5.3.15
DE   Protein-arginine deiminase.
CA   Protein L-arginine + H(2)O = protein L-citrulline + NH(3).
CC   -!- Also acts on N-acyl-L-arginine and, more slowly, on L-arginine
CC       esters.
DR   Q9ULC6, PADI1_HUMAN;  Q9Z185, PADI1_MOUSE;  O88806, PADI1_RAT  ;
DR   Q9Y2J8, PADI2_HUMAN;  Q08642, PADI2_MOUSE;  P20717, PADI2_RAT  ;
DR   Q9ULW8, PADI3_HUMAN;  Q9Z184, PADI3_MOUSE;  P70708, PADI3_RAT  ;
DR   O02849, PADI3_SHEEP;  Q9UM07, PADI4_HUMAN;  Q9Z183, PADI4_MOUSE;
DR   O88807, PADI4_RAT  ;  Q6TGC4, PADI6_HUMAN;  Q8K3V4, PADI6_MOUSE;
//
ID   3.5.3.16
DE   Methylguanidinase.
CA   Methylguanidine + H(2)O = methylamine + urea.
CC   -!- Acts on other alkylguanidines, very slowly.
//
ID   3.5.3.17
DE   Guanidinopropionase.
CA   3-guanidinopropanoate + H(2)O = beta-alanine + urea.
CF   Manganese.
CC   -!- Also acts, more slowly, on taurocyamine and 4-guanidinobutanoate.
//
ID   3.5.3.18
DE   Dimethylargininase.
AN   Dimethylarginine dimethylaminohydrolase.
AN   N(G),N(G)-dimethylarginine dimethylaminohydrolase.
CA   N(omega),N(omega)-dimethyl-L-arginine + H(2)O = dimethylamine +
CA   L-citrulline.
CC   -!- Also acts on N(omega)-methyl-L-arginine.
DR   P56965, DDAH1_BOVIN;  O94760, DDAH1_HUMAN;  Q9CWS0, DDAH1_MOUSE;
DR   O08557, DDAH1_RAT  ;  Q3SX44, DDAH2_BOVIN;  O95865, DDAH2_HUMAN;
DR   Q99LD8, DDAH2_MOUSE;  Q6MG60, DDAH2_RAT  ;  Q9I4E3, DDAH_PSEAE ;
DR   Q9X7M4, DDAH_STRCO ;
//
ID   3.5.3.19
DE   Ureidoglycolate hydrolase.
CA   (S)-ureidoglycolate + H(2)O = glyoxylate + 2 NH(3) + CO(2).
DR   Q92UG4, ALLA1_RHIME;  Q92TW1, ALLA2_RHIME;  Q8UD04, ALLA_AGRT5 ;
DR   C1DFA8, ALLA_AZOVD ;  B2SA00, ALLA_BRUA1 ;  Q2YMM3, ALLA_BRUA2 ;
DR   Q57EL6, ALLA_BRUAB ;  A9M929, ALLA_BRUC2 ;  C0RHL3, ALLA_BRUMB ;
DR   Q8YFU0, ALLA_BRUME ;  A5VP72, ALLA_BRUO2 ;  B0CKJ0, ALLA_BRUSI ;
DR   P59284, ALLA_BRUSU ;  Q9AP01, ALLA_BURCE ;  A3MKP1, ALLA_BURM7 ;
DR   A2SBC3, ALLA_BURM9 ;  Q62JH1, ALLA_BURMA ;  A1V517, ALLA_BURMS ;
DR   A7ZIR2, ALLA_ECO24 ;  B7UKI3, ALLA_ECO27 ;  B7ME28, ALLA_ECO45 ;
DR   B7L7D2, ALLA_ECO55 ;  P63486, ALLA_ECO57 ;  B5YPM2, ALLA_ECO5E ;
DR   B7MQL7, ALLA_ECO81 ;  B7M4K9, ALLA_ECO8A ;  C4ZUV5, ALLA_ECOBW ;
DR   B1XFU0, ALLA_ECODH ;  A7ZXF9, ALLA_ECOHS ;  A1A8H1, ALLA_ECOK1 ;
DR   Q0TKD6, ALLA_ECOL5 ;  Q8FK65, ALLA_ECOL6 ;  B1IZ95, ALLA_ECOLC ;
DR   P77731, ALLA_ECOLI ;  B7N960, ALLA_ECOLU ;  B6I0F6, ALLA_ECOSE ;
DR   B1LKC4, ALLA_ECOSM ;  Q1RF29, ALLA_ECOUT ;  Q11EH0, ALLA_MESSB ;
DR   A6WWR5, ALLA_OCHA4 ;  Q48KS5, ALLA_PSE14 ;  A6V7Z0, ALLA_PSEA7 ;
DR   B7UW34, ALLA_PSEA8 ;  Q02JZ7, ALLA_PSEAB ;  Q9I3J9, ALLA_PSEAE ;
DR   Q1ICT0, ALLA_PSEE4 ;  Q4K8H2, ALLA_PSEF5 ;  C3K0A8, ALLA_PSEFS ;
DR   A5W0S6, ALLA_PSEP1 ;  Q3KFL0, ALLA_PSEPF ;  B0KPY7, ALLA_PSEPG ;
DR   P59285, ALLA_PSEPK ;  B1JC20, ALLA_PSEPW ;  Q87YX3, ALLA_PSESM ;
DR   Q4ZVG9, ALLA_PSEU2 ;  A4VP33, ALLA_PSEU5 ;  B3PW72, ALLA_RHIE6 ;
DR   Q2K5I1, ALLA_RHIEC ;  Q98CJ0, ALLA_RHILO ;  B5ZZ10, ALLA_RHILW ;
DR   O68109, ALLA_RHOCB ;  B5EYB6, ALLA_SALA4 ;  B5FLM6, ALLA_SALDC ;
DR   Q9S4Y6, ALLA_SALEN ;  B5QUS9, ALLA_SALEP ;  B5R639, ALLA_SALG2 ;
DR   B4T9K8, ALLA_SALHS ;  B4SXM1, ALLA_SALNS ;  Q5PCF4, ALLA_SALPA ;
DR   A9MW53, ALLA_SALPB ;  B5BD17, ALLA_SALPK ;  Q8ZR87, ALLA_SALTY ;
DR   O13843, ALLA_SCHPO ;  B2TTA4, ALLA_SHIB3 ;  Q324Z1, ALLA_SHIBS ;
DR   Q32J98, ALLA_SHIDS ;  Q0T788, ALLA_SHIF8 ;  P63487, ALLA_SHIFL ;
DR   P32459, ALLA_YEAST ;  Q8UFI8, ALLH_AGRT5 ;
//
ID   3.5.3.20
DE   Diguanidinobutanase.
CA   1,4-diguanidinobutane + H(2)O = agmatine + urea.
CC   -!- Other diguanidinoalkanes with 3 to 10 methylene groups can act, more
CC       slowly.
//
ID   3.5.3.21
DE   Methylenediurea deaminase.
AN   Methylenediurease.
CA   NH(2)-CO-NH-CH(2)-NH-CO-NH(2) + 2 H(2)O = N-(hydroxymethyl)urea + 2 NH(3)
CA   + CO(2).
CC   -!- The methylenediurea is hydrolyzed and decarboxylated to give an
CC       aminated methylurea, which then spontaneously hydrolyzes to
CC       hydroxymethylurea.
CC   -!- The enzyme from Ochrobactrum anthropi also hydrolyzes
CC       dimethylenetriurea and trimethylenetetraurea as well as
CC       ureidoglycolate, which is hydrolyzed to urea and glyoxylate,
CC       and allantoate, which is hydrolyzed to ureidoglycolate, ammonia and
CC       carbon dioxide.
//
ID   3.5.3.22
DE   Proclavaminate amidinohydrolase.
AN   PAH.
AN   Proclavaminate amidino hydrolase.
AN   Proclavaminic acid amidino hydrolase.
CA   Amidinoproclavaminate + H(2)O = proclavaminate + urea.
CF   Manganese.
CC   -!- Forms part of the pathway for the biosythesis of the beta-lactamase
CC       inhibitor clavulanate in Streptomyces clavuligerus.
CC   -!- It carries out an intermediary reaction between the first reaction of
CC       EC 1.14.11.21, and the second and third reactions of that enzyme.
PR   PROSITE; PDOC00135;
DR   P37819, PAH_STRCL  ;
//
ID   3.5.3.23
DE   N-succinylarginine dihydrolase.
AN   Arginine succinylhydrolase.
AN   N(2)-succinylarginine dihydrolase.
AN   SADH.
CA   N(2)-succinyl-L-arginine + 2 H(2)O = N(2)-succinyl-L-ornithine + 2 NH(3)
CA   + CO(2).
CC   -!- Arginine, N(2)-acetylarginine and N(2)-glutamylarginine do not act as
CC       substrates.
CC   -!- The second enzyme in the arginine succinyltransferase (AST) pathway
CC       for the catabolism of arginine.
CC   -!- This pathway converts the carbon skeleton of arginine into glutamate,
CC       with the concomitant production of ammonia and conversion of
CC       succinyl-CoA into succinate and CoA.
CC   -!- The five enzymes involved in this pathway are EC 2.3.1.109,
CC       EC 3.5.3.23, EC 2.6.1.11, EC 1.2.1.71 and EC 3.5.1.96.
DR   Q9AAL4, ASTB1_CAUCR;  Q9A7W1, ASTB2_CAUCR;  Q6FCP9, ASTB_ACIAD ;
DR   B7GVV0, ASTB_ACIB3 ;  B7IA89, ASTB_ACIB5 ;  B2HZS3, ASTB_ACIBC ;
DR   B0VQ88, ASTB_ACIBS ;  A3M9D2, ASTB_ACIBT ;  B0V7X3, ASTB_ACIBY ;
DR   A0KMV4, ASTB_AERHH ;  B6EQ59, ASTB_ALISL ;  B4S1Q6, ASTB_ALTMD ;
DR   B1YW20, ASTB_BURA4 ;  Q1BXP0, ASTB_BURCA ;  B1JYT6, ASTB_BURCC ;
DR   A0K609, ASTB_BURCH ;  B4ECZ9, ASTB_BURCJ ;  Q0BGU9, ASTB_BURCM ;
DR   A9AD18, ASTB_BURM1 ;  A3MLY7, ASTB_BURM7 ;  A2SA47, ASTB_BURM9 ;
DR   Q62LN4, ASTB_BURMA ;  A1V674, ASTB_BURMS ;  A3NXG1, ASTB_BURP0 ;
DR   Q3JQC7, ASTB_BURP1 ;  A3NBM6, ASTB_BURP6 ;  B2JCG4, ASTB_BURP8 ;
DR   B2T314, ASTB_BURPP ;  Q63SD8, ASTB_BURPS ;  Q39I24, ASTB_BURS3 ;
DR   Q2SXN8, ASTB_BURTA ;  A4JCW1, ASTB_BURVG ;  Q141D2, ASTB_BURXL ;
DR   Q1QTQ8, ASTB_CHRSD ;  Q7NXX6, ASTB_CHRVO ;  A8AHD7, ASTB_CITK8 ;
DR   A7ZML3, ASTB_ECO24 ;  B7USC6, ASTB_ECO27 ;  B7MAV6, ASTB_ECO45 ;
DR   B7L6L9, ASTB_ECO55 ;  Q7ADE7, ASTB_ECO57 ;  B5YQ32, ASTB_ECO5E ;
DR   B7NT32, ASTB_ECO7I ;  B7MVM4, ASTB_ECO81 ;  B7M1F7, ASTB_ECO8A ;
DR   C4ZZA1, ASTB_ECOBW ;  B1XGK6, ASTB_ECODH ;  A8A0T7, ASTB_ECOHS ;
DR   A1ABS6, ASTB_ECOK1 ;  Q0TH85, ASTB_ECOL5 ;  Q8FH02, ASTB_ECOL6 ;
DR   B1IPI5, ASTB_ECOLC ;  P76216, ASTB_ECOLI ;  B7N581, ASTB_ECOLU ;
DR   B6IBG5, ASTB_ECOSE ;  B1LDY6, ASTB_ECOSM ;  Q1RB48, ASTB_ECOUT ;
DR   A4W9J8, ASTB_ENT38 ;  A7MNV7, ASTB_ENTS8 ;  B2VEK6, ASTB_ERWT9 ;
DR   B7LQ47, ASTB_ESCF3 ;  Q2SKP0, ASTB_HAHCH ;  Q5QWI1, ASTB_IDILO ;
DR   Q5X4K3, ASTB_LEGPA ;  A5ICK4, ASTB_LEGPC ;  Q5ZUT4, ASTB_LEGPH ;
DR   Q5WVZ3, ASTB_LEGPL ;  A1U5W7, ASTB_MARAV ;  Q1DDF6, ASTB_MYXXD ;
DR   Q2Y8M6, ASTB_NITMU ;  Q2G9Z6, ASTB_NOVAD ;  Q7N2H0, ASTB_PHOLL ;
DR   Q6LJR6, ASTB_PHOPR ;  Q48G20, ASTB_PSE14 ;  Q15TB5, ASTB_PSEA6 ;
DR   A6VA75, ASTB_PSEA7 ;  B7UY35, ASTB_PSEA8 ;  Q02I59, ASTB_PSEAB ;
DR   O50175, ASTB_PSEAE ;  Q1I6Z6, ASTB_PSEE4 ;  Q4K838, ASTB_PSEF5 ;
DR   C3JXY6, ASTB_PSEFS ;  Q3ID31, ASTB_PSEHT ;  A4XWE6, ASTB_PSEMY ;
DR   A5W0D6, ASTB_PSEP1 ;  Q3K886, ASTB_PSEPF ;  B0KR46, ASTB_PSEPG ;
DR   Q88EI5, ASTB_PSEPK ;  B1JCH2, ASTB_PSEPW ;  Q885J6, ASTB_PSESM ;
DR   Q4ZQH9, ASTB_PSEU2 ;  B5F7I9, ASTB_SALA4 ;  A9MFF9, ASTB_SALAR ;
DR   B5FJD5, ASTB_SALDC ;  B5QWI7, ASTB_SALEP ;  B5RAZ8, ASTB_SALG2 ;
DR   B4TGE3, ASTB_SALHS ;  B4T3Z7, ASTB_SALNS ;  Q5PHC1, ASTB_SALPA ;
DR   A9N275, ASTB_SALPB ;  B5BA69, ASTB_SALPK ;  B4TUC4, ASTB_SALSV ;
DR   Q8Z6G2, ASTB_SALTI ;  Q8ZPU9, ASTB_SALTY ;  A8GFQ2, ASTB_SERP5 ;
DR   A1S572, ASTB_SHEAM ;  B8E786, ASTB_SHEB2 ;  A3D5H7, ASTB_SHEB5 ;
DR   A6WP88, ASTB_SHEB8 ;  A9L516, ASTB_SHEB9 ;  Q12LR7, ASTB_SHEDO ;
DR   Q080J1, ASTB_SHEFN ;  B0TP13, ASTB_SHEHH ;  A3QF43, ASTB_SHELP ;
DR   Q8EDN7, ASTB_SHEON ;  A8H2S2, ASTB_SHEPA ;  A4Y7N9, ASTB_SHEPC ;
DR   B8CN09, ASTB_SHEPW ;  A0KVZ2, ASTB_SHESA ;  A8FX76, ASTB_SHESH ;
DR   A1RIU9, ASTB_SHESW ;  B1KNK9, ASTB_SHEWM ;  Q321N7, ASTB_SHIBS ;
DR   Q32G87, ASTB_SHIDS ;  Q3Z293, ASTB_SHISS ;  Q1GRR9, ASTB_SPHAL ;
DR   A5V3M9, ASTB_SPHWW ;  Q5DZ79, ASTB_VIBF1 ;  B5EV09, ASTB_VIBFM ;
DR   A1JS35, ASTB_YERE8 ;  A7FIL3, ASTB_YERP3 ;  Q1C8A8, ASTB_YERPA ;
DR   B2K297, ASTB_YERPB ;  Q8D0D8, ASTB_YERPE ;  A9QZ60, ASTB_YERPG ;
DR   A4TJU4, ASTB_YERPP ;  Q66B18, ASTB_YERPS ;  B1JMD0, ASTB_YERPY ;
DR   Q5NNB4, ASTB_ZYMMO ;
//
ID   3.5.4.1
DE   Cytosine deaminase.
AN   Cytosine aminohydrolase.
CA   Cytosine + H(2)O = uracil + NH(3).
CC   -!- Also acts on 5-methylcytosine.
DR   P25524, CODA_ECOLI ;  P78594, FCA1_CANAL ;  Q12178, FCY1_YEAST ;
DR   O59834, FCYS_SCHPO ;
//
ID   3.5.4.2
DE   Adenine deaminase.
AN   Adenase.
AN   Adenine aminase.
CA   Adenine + H(2)O = hypoxanthine + NH(3).
DR   Q7CXF0, ADEC1_AGRT5;  Q5WJ39, ADEC1_BACSK;  Q89QG3, ADEC1_BRAJA;
DR   A4YQV7, ADEC1_BRASO;  Q3AE90, ADEC1_CARHZ;  Q6ANH2, ADEC1_DESPS;
DR   Q28VK7, ADEC1_JANSC;  Q38ZJ0, ADEC1_LACSS;  Q04HC1, ADEC1_OENOB;
DR   Q2K5M6, ADEC1_RHIEC;  Q1MDE8, ADEC1_RHIL3;  Q92N33, ADEC1_RHIME;
DR   Q7CUX4, ADEC2_AGRT5;  Q5WD17, ADEC2_BACSK;  Q89H53, ADEC2_BRAJA;
DR   A4YXM5, ADEC2_BRASO;  Q3AE81, ADEC2_CARHZ;  Q6ANH1, ADEC2_DESPS;
DR   Q28MB2, ADEC2_JANSC;  Q38V07, ADEC2_LACSS;  Q04DZ9, ADEC2_OENOB;
DR   Q2K4Q9, ADEC2_RHIEC;  Q1MCF8, ADEC2_RHIL3;  Q92VC6, ADEC2_RHIME;
DR   Q1M901, ADEC3_RHIL3;  Q92YE2, ADEC3_RHIME;  Q92YE0, ADEC4_RHIME;
DR   O29999, ADEC_ARCFU ;  A7Z463, ADEC_BACA2 ;  Q9KF46, ADEC_BACHD ;
DR   Q65K51, ADEC_BACLD ;  A8FCR4, ADEC_BACP2 ;  P39761, ADEC_BACSU ;
DR   Q6MJY0, ADEC_BDEBA ;  Q0SLI9, ADEC_BORAP ;  O50821, ADEC_BORBU ;
DR   A5EGE2, ADEC_BRASB ;  Q2YKR3, ADEC_BRUA2 ;  Q578E4, ADEC_BRUAB ;
DR   Q8YCA5, ADEC_BRUME ;  Q8FW12, ADEC_BRUSU ;  A0RZ37, ADEC_CENSY ;
DR   Q97KN0, ADEC_CLOAB ;  A7FQU9, ADEC_CLOB1 ;  C3KZB6, ADEC_CLOB6 ;
DR   B2V525, ADEC_CLOBA ;  B2TJH6, ADEC_CLOBB ;  A7GA53, ADEC_CLOBL ;
DR   B1KTS4, ADEC_CLOBM ;  Q187C8, ADEC_CLOD6 ;  Q0TR21, ADEC_CLOP1 ;
DR   Q8XKX4, ADEC_CLOPE ;  Q3Z8C6, ADEC_DEHE1 ;  A5FR71, ADEC_DEHSB ;
DR   Q3ZXH1, ADEC_DEHSC ;  C1CZZ4, ADEC_DEIDV ;  Q1J1B1, ADEC_DEIGD ;
DR   Q9RYP0, ADEC_DEIRA ;  B8FLT9, ADEC_DESAA ;  Q317F9, ADEC_DESDG ;
DR   B8FPU4, ADEC_DESHD ;  Q24R88, ADEC_DESHY ;  A4J872, ADEC_DESRM ;
DR   Q72EX7, ADEC_DESVH ;  A1VGE5, ADEC_DESVV ;  A7ZTM0, ADEC_ECO24 ;
DR   B7MFN5, ADEC_ECO45 ;  B7L789, ADEC_ECO55 ;  Q7A9L5, ADEC_ECO57 ;
DR   B5YX72, ADEC_ECO5E ;  B7NQW3, ADEC_ECO7I ;  B7N1X4, ADEC_ECO81 ;
DR   B7M4F2, ADEC_ECO8A ;  C4ZXQ7, ADEC_ECOBW ;  B1X998, ADEC_ECODH ;
DR   A8A6C8, ADEC_ECOHS ;  A1AHK5, ADEC_ECOK1 ;  Q0TB37, ADEC_ECOL5 ;
DR   Q8FBX7, ADEC_ECOL6 ;  B1IYS4, ADEC_ECOLC ;  P31441, ADEC_ECOLI ;
DR   B7NEX9, ADEC_ECOLU ;  B6I3P6, ADEC_ECOSE ;  B1LKZ0, ADEC_ECOSM ;
DR   Q1R4R6, ADEC_ECOUT ;  C5BF52, ADEC_EDWI9 ;  Q835Z6, ADEC_ENTFA ;
DR   B7LK09, ADEC_ESCF3 ;  A6GYI0, ADEC_FLAPJ ;  Q5KY53, ADEC_GEOKA ;
DR   Q5FQ87, ADEC_GLUOX ;  B5XP95, ADEC_KLEP3 ;  A6TBK1, ADEC_KLEP7 ;
DR   C5CI63, ADEC_KOSOT ;  Q1G825, ADEC_LACDA ;  Q88SR1, ADEC_LACPL ;
DR   Q1WTM3, ADEC_LACS1 ;  B1MY57, ADEC_LEUCK ;  Q03YC9, ADEC_LEUMM ;
DR   Q92AR6, ADEC_LISIN ;  Q71YS6, ADEC_LISMF ;  Q8Y6E5, ADEC_LISMO ;
DR   A0AJJ5, ADEC_LISW6 ;  B1HR71, ADEC_LYSSC ;  Q11JE6, ADEC_MESSB ;
DR   A6UVJ0, ADEC_META3 ;  Q8TNH5, ADEC_METAC ;  A7I8N1, ADEC_METB6 ;
DR   Q466H2, ADEC_METBF ;  Q12XX8, ADEC_METBU ;  Q58854, ADEC_METJA ;
DR   Q8TX47, ADEC_METKA ;  Q8PT13, ADEC_METMA ;  A3CVR8, ADEC_METMJ ;
DR   B8IB34, ADEC_METNO ;  A5ULK1, ADEC_METS3 ;  B0UDG6, ADEC_METS4 ;
DR   Q2NER8, ADEC_METST ;  O26952, ADEC_METTH ;  A0B6I9, ADEC_METTP ;
DR   Q2RL95, ADEC_MOOTA ;  Q8CUS7, ADEC_OCEIH ;  A6X5D7, ADEC_OCHA4 ;
DR   A6LG60, ADEC_PARD8 ;  A1B5X6, ADEC_PARDP ;  A9BIU9, ADEC_PETMO ;
DR   Q98NF9, ADEC_RHILO ;  C3MG57, ADEC_RHISN ;  A3PN31, ADEC_RHOS1 ;
DR   Q3IZ66, ADEC_RHOS4 ;  A4WP35, ADEC_RHOS5 ;  B9KND1, ADEC_RHOSK ;
DR   Q16CI8, ADEC_ROSDO ;  Q1AZ25, ADEC_RUBXD ;  Q2S006, ADEC_SALRD ;
DR   A8GAT0, ADEC_SERP5 ;  B0TMM7, ADEC_SHEHH ;  Q31US8, ADEC_SHIBS ;
DR   Q329F0, ADEC_SHIDS ;  Q0SYL1, ADEC_SHIF8 ;  Q7BZ90, ADEC_SHIFL ;
DR   Q3YWE3, ADEC_SHISS ;  Q5LM18, ADEC_SILPO ;  Q1GCT5, ADEC_SILST ;
DR   A3DLI4, ADEC_STAMF ;  A6Q8K5, ADEC_SULNB ;  A0LFB5, ADEC_SYNFM ;
DR   B7IEM2, ADEC_THEAB ;  A6LNR9, ADEC_THEM4 ;  Q6FCU0, ADE_ACIAD  ;
DR   B9J6V8, ADE_AGRRK  ;  Q8UJ05, ADE_AGRT5  ;  B9JYP8, ADE_AGRVS  ;
DR   Q4X1Q4, ADE_ASPFU  ;  Q2TZN9, ADE_ASPOR  ;  C1DGB0, ADE_AZOVD  ;
DR   Q2KWR7, ADE_BORA1  ;  Q7WMY6, ADE_BORBR  ;  Q7WBG5, ADE_BORPA  ;
DR   B2T672, ADE_BURPP  ;  Q13V90, ADE_BURXL  ;  B9KE87, ADE_CAMLR  ;
DR   Q59ZB1, ADE_CANAL  ;  Q6FP78, ADE_CANGA  ;  B8H3Z4, ADE_CAUCN  ;
DR   Q9A3M3, ADE_CAUCR  ;  B3EL75, ADE_CHLPB  ;  Q0KCW5, ADE_CUPNH  ;
DR   Q46YJ3, ADE_CUPPJ  ;  B3R3T1, ADE_CUPTR  ;  B1WR40, ADE_CYAA5  ;
DR   Q8X1T6, ADE_EMENI  ;  B3E600, ADE_GEOLS  ;  A5G460, ADE_GEOUR  ;
DR   Q4IMJ1, ADE_GIBZE  ;  Q2SLW3, ADE_HAHCH  ;  Q6CM42, ADE_KLULA  ;
DR   A6VWL7, ADE_MARMS  ;  Q11C48, ADE_MESSB  ;  Q3B2Q0, ADE_PELLD  ;
DR   Q48D01, ADE_PSE14  ;  A6UXT7, ADE_PSEA7  ;  B7V265, ADE_PSEA8  ;
DR   Q02UT0, ADE_PSEAB  ;  Q9I6Y4, ADE_PSEAE  ;  Q1IFE4, ADE_PSEE4  ;
DR   Q4KIS2, ADE_PSEF5  ;  C3K8W2, ADE_PSEFS  ;  A4XYN8, ADE_PSEMY  ;
DR   Q3KIJ1, ADE_PSEPF  ;  B0KLE3, ADE_PSEPG  ;  Q88QA3, ADE_PSEPK  ;
DR   B1JFB0, ADE_PSEPW  ;  Q889J2, ADE_PSESM  ;  Q4ZYP1, ADE_PSEU2  ;
DR   A4VQI5, ADE_PSEU5  ;  Q1QDL4, ADE_PSYCK  ;  Q1LQ00, ADE_RALME  ;
DR   B2U7U6, ADE_RALPJ  ;  Q8XXL5, ADE_RALSO  ;  B3PXN1, ADE_RHIE6  ;
DR   Q2KDR5, ADE_RHIEC  ;  Q1MMV7, ADE_RHIL3  ;  Q98GV2, ADE_RHILO  ;
DR   B5ZXI3, ADE_RHILW  ;  Q92T48, ADE_RHIME  ;  C3MBH4, ADE_RHISN  ;
DR   Q21T97, ADE_RHOFD  ;  Q20YN2, ADE_RHOPB  ;  Q2RWC5, ADE_RHORT  ;
DR   Q9P6I7, ADE_SCHPO  ;  A6UET5, ADE_SINMW  ;  Q1GRK2, ADE_SPHAL  ;
DR   Q9RDE5, ADE_STRCO  ;  Q87GM3, ADE_VIBPA  ;  Q7M9R5, ADE_WOLSU  ;
DR   P53909, ADE_YEAST  ;  Q5NNW5, ADE_ZYMMO  ;  Q6L032, Y1085_PICTO;
DR   Q81BX6, Y3012_BACCR;  Q6HX62, Y3032_BACAN;  Q9KF49, Y637_BACHD ;
DR   Q8ES91, Y751_OCEIH ;  O34909, YERA_BACSU ;
//
ID   3.5.4.3
DE   Guanine deaminase.
AN   GAH.
AN   Guanase.
AN   Guanine aminase.
CA   Guanine + H(2)O = xanthine + NH(3).
DR   O34598, GUAD_BACSU ;  Q9RYX4, GUAD_DEIRA ;  Q86AW9, GUAD_DICDI ;
DR   P76641, GUAD_ECOLI ;  Q9Y2T3, GUAD_HUMAN ;  Q9R111, GUAD_MOUSE ;
DR   Q5RAV9, GUAD_PONAB ;  Q9WTT6, GUAD_RAT   ;  O14057, GUAD_SCHPO ;
DR   Q07729, GUAD_YEAST ;
//
ID   3.5.4.4
DE   Adenosine deaminase.
AN   Adenosine aminohydrolase.
CA   Adenosine + H(2)O = inosine + NH(3).
PR   PROSITE; PDOC00419;
DR   P84520, ADA2_CHICK ;  P56658, ADA_BOVIN  ;  Q5ZKP6, ADA_CHICK  ;
DR   Q6DG22, ADA_DANRE  ;  Q54KF3, ADA_DICDI  ;  P00813, ADA_HUMAN  ;
DR   P03958, ADA_MOUSE  ;  Q920P6, ADA_RAT    ;  Q6GP70, ADA_XENLA  ;
DR   Q63ZU0, ADA_XENTR  ;  Q9AK25, ADD1_STRCO ;  Q9X7T2, ADD2_STRCO ;
DR   Q97EV1, ADD_CLOAB  ;  A7FSN7, ADD_CLOB1  ;  C3L357, ADD_CLOB6  ;
DR   A5I0I2, ADD_CLOBH  ;  C1FVJ1, ADD_CLOBJ  ;  B1IHX4, ADD_CLOBK  ;
DR   A7GC28, ADD_CLOBL  ;  B1KY93, ADD_CLOBM  ;  B9DZX5, ADD_CLOK1  ;
DR   A5N6F5, ADD_CLOK5  ;  Q0TME7, ADD_CLOP1  ;  Q8XHH8, ADD_CLOPE  ;
DR   Q0SQ45, ADD_CLOPS  ;  A7ZM83, ADD_ECO24  ;  B7URW2, ADD_ECO27  ;
DR   B7M9X6, ADD_ECO45  ;  B7L5H5, ADD_ECO55  ;  Q8X661, ADD_ECO57  ;
DR   B5Z457, ADD_ECO5E  ;  B7NU11, ADD_ECO7I  ;  B7MVA0, ADD_ECO81  ;
DR   B7M0H9, ADD_ECO8A  ;  C4ZY85, ADD_ECOBW  ;  B1XF88, ADD_ECODH  ;
DR   A8A0G5, ADD_ECOHS  ;  A1ABG8, ADD_ECOK1  ;  Q0THK5, ADD_ECOL5  ;
DR   Q8FH99, ADD_ECOL6  ;  B1IQD2, ADD_ECOLC  ;  P22333, ADD_ECOLI  ;
DR   B7NB76, ADD_ECOLU  ;  B6IB57, ADD_ECOSE  ;  B1LER3, ADD_ECOSM  ;
DR   Q1RBH5, ADD_ECOUT  ;  C5BDE0, ADD_EDWI9  ;  A4W9X4, ADD_ENT38  ;
DR   Q839J4, ADD_ENTFA  ;  Q6D4X4, ADD_ERWCT  ;  B2VK11, ADD_ERWT9  ;
DR   Q7VNV1, ADD_HAEDU  ;  B5XWQ7, ADD_KLEP3  ;  A6T9W8, ADD_KLEP7  ;
DR   Q036B8, ADD_LACC3  ;  B3W9T6, ADD_LACCB  ;  Q9CIR9, ADD_LACLA  ;
DR   A0QKJ4, ADD_MYCA1  ;  B1MFZ9, ADD_MYCA9  ;  P63908, ADD_MYCBO  ;
DR   A1KP00, ADD_MYCBP  ;  A4TEW1, ADD_MYCGI  ;  B8ZUW8, ADD_MYCLB  ;
DR   Q9CCL9, ADD_MYCLE  ;  B2HDU8, ADD_MYCMM  ;  Q73UD0, ADD_MYCPA  ;
DR   A3PVY4, ADD_MYCSJ  ;  A1UCA4, ADD_MYCSK  ;  Q1BCN9, ADD_MYCSS  ;
DR   A5U7Y8, ADD_MYCTA  ;  P63907, ADD_MYCTU  ;  A0PNJ1, ADD_MYCUA  ;
DR   A1T5H1, ADD_MYCVP  ;  C6DH28, ADD_PECCP  ;  Q7N4H5, ADD_PHOLL  ;
DR   B4EVZ1, ADD_PROMH  ;  Q3IF68, ADD_PSEHT  ;  B5F6I4, ADD_SALA4  ;
DR   B5FIE1, ADD_SALDC  ;  B5QUG0, ADD_SALEP  ;  B5RAJ6, ADD_SALG2  ;
DR   B4THP5, ADD_SALHS  ;  B4T5A0, ADD_SALNS  ;  C0Q502, ADD_SALPC  ;
DR   B4TVC7, ADD_SALSV  ;  Q8Z6R2, ADD_SALTI  ;  Q8ZPL9, ADD_SALTY  ;
DR   A8GE12, ADD_SERP5  ;  A1S1P1, ADD_SHEAM  ;  B8EDT7, ADD_SHEB2  ;
DR   A3CYL9, ADD_SHEB5  ;  A6WUH7, ADD_SHEB8  ;  A9KWZ3, ADD_SHEB9  ;
DR   Q12I24, ADD_SHEDO  ;  Q08A11, ADD_SHEFN  ;  B0TT81, ADD_SHEHH  ;
DR   A3QJD9, ADD_SHELP  ;  Q8E8D4, ADD_SHEON  ;  A8H819, ADD_SHEPA  ;
DR   A4YCD7, ADD_SHEPC  ;  B8CV32, ADD_SHEPW  ;  A0L2R5, ADD_SHESA  ;
DR   Q0HD92, ADD_SHESM  ;  Q0HPH4, ADD_SHESR  ;  A1RDZ6, ADD_SHESW  ;
DR   B1KHA6, ADD_SHEWM  ;  B2U2C1, ADD_SHIB3  ;  Q320Y0, ADD_SHIBS  ;
DR   Q32FF0, ADD_SHIDS  ;  Q0T4F4, ADD_SHIF8  ;  Q83RC0, ADD_SHIFL  ;
DR   Q3Z1X8, ADD_SHISS  ;  Q3K2D4, ADD_STRA1  ;  P63909, ADD_STRA3  ;
DR   P63910, ADD_STRA5  ;  C0M691, ADD_STRE4  ;  B4U295, ADD_STREM  ;
DR   Q8DTN8, ADD_STRMU  ;  C0MHB1, ADD_STRS7  ;  Q5M4W6, ADD_STRT2  ;
DR   Q03L81, ADD_STRTD  ;  A5F4Q2, ADD_VIBC3  ;  Q9KNI7, ADD_VIBCH  ;
DR   C3LSH8, ADD_VIBCM  ;  Q5E8Q8, ADD_VIBF1  ;  B5FFC4, ADD_VIBFM  ;
DR   Q87TF3, ADD_VIBPA  ;  B7VQ44, ADD_VIBSL  ;  Q8D6Q8, ADD_VIBVU  ;
DR   Q7MDL6, ADD_VIBVY  ;  A1JML4, ADD_YERE8  ;  A7FHX5, ADD_YERP3  ;
DR   B2K4L5, ADD_YERPB  ;  Q66AF0, ADD_YERPS  ;  B1JKL9, ADD_YERPY  ;
DR   P15287, AGSA_APLCA ;  P58781, CEC1A_DANRE;  Q553U5, CECR1_DICDI;
DR   Q9NZK5, CECR1_HUMAN;  P58780, CECR1_PIG  ;  Q5RC46, CECR1_PONAB;
DR   Q2VQV9, CECR1_XENLA;
//
ID   3.5.4.5
DE   Cytidine deaminase.
AN   Cytidine aminohydrolase.
AN   Cytosine nucleoside deaminase.
CA   Cytidine + H(2)O = uridine + NH(3).
PR   PROSITE; PDOC00702;
DR   Q2PT36, AICDA_BOVIN;  Q75W64, AICDA_CANFA;  Q9GZX7, AICDA_HUMAN;
DR   Q9WVE0, AICDA_MOUSE;  A3N1Z1, CDD_ACTP2  ;  B3GYC3, CDD_ACTP7  ;
DR   B0BQT2, CDD_ACTPJ  ;  A6VLF5, CDD_ACTSZ  ;  A0KJH4, CDD_AERHH  ;
DR   A4SNI2, CDD_AERS4  ;  Q9KD53, CDD_BACHD  ;  Q9S3M0, CDD_BACPY  ;
DR   P19079, CDD_BACSU  ;  A8AE87, CDD_CITK8  ;  Q54I82, CDD_DICDI  ;
DR   A7ZNW5, CDD_ECO24  ;  B7UFF9, CDD_ECO27  ;  B7MF55, CDD_ECO45  ;
DR   B7LA09, CDD_ECO55  ;  Q8X648, CDD_ECO57  ;  B5YW75, CDD_ECO5E  ;
DR   B7NMA8, CDD_ECO7I  ;  B7MXF5, CDD_ECO81  ;  B7M4Y8, CDD_ECO8A  ;
DR   C4ZSM3, CDD_ECOBW  ;  B1X7N2, CDD_ECODH  ;  A8A204, CDD_ECOHS  ;
DR   A1AD04, CDD_ECOK1  ;  Q0TFU8, CDD_ECOL5  ;  Q8FFV3, CDD_ECOL6  ;
DR   B1IYC6, CDD_ECOLC  ;  P0ABF6, CDD_ECOLI  ;  B7NCH2, CDD_ECOLU  ;
DR   B6I8J3, CDD_ECOSE  ;  B1LKP0, CDD_ECOSM  ;  Q1R9T0, CDD_ECOUT  ;
DR   C5BCM4, CDD_EDWI9  ;  A4WCI1, CDD_ENT38  ;  A7MLJ4, CDD_ENTS8  ;
DR   Q6D3B4, CDD_ERWCT  ;  B2VIF3, CDD_ERWT9  ;  B7LVA3, CDD_ESCF3  ;
DR   Q7VMJ6, CDD_HAEDU  ;  Q4QK60, CDD_HAEI8  ;  A5UBV9, CDD_HAEIE  ;
DR   A5UEI7, CDD_HAEIG  ;  P44325, CDD_HAEIN  ;  Q0I4X6, CDD_HAES1  ;
DR   B0USP2, CDD_HAES2  ;  P32320, CDD_HUMAN  ;  B5XP65, CDD_KLEP3  ;
DR   A6TBN1, CDD_KLEP7  ;  Q65RG8, CDD_MANSM  ;  P56389, CDD_MOUSE  ;
DR   P47298, CDD_MYCGE  ;  P47718, CDD_MYCPI  ;  P75051, CDD_MYCPN  ;
DR   Q9CP11, CDD_PASMU  ;  C6DDS7, CDD_PECCP  ;  Q7N6K3, CDD_PHOLL  ;
DR   Q6LRI0, CDD_PHOPR  ;  B4ESY3, CDD_PROMH  ;  Q3IBX5, CDD_PSEHT  ;
DR   B5EYN3, CDD_SALA4  ;  A9MKS5, CDD_SALAR  ;  Q57MF5, CDD_SALCH  ;
DR   B5FMZ9, CDD_SALDC  ;  B5R153, CDD_SALEP  ;  B5RC22, CDD_SALG2  ;
DR   B4TAK5, CDD_SALHS  ;  B4SY15, CDD_SALNS  ;  Q5PE68, CDD_SALPA  ;
DR   A9N6L3, CDD_SALPB  ;  C0Q0V4, CDD_SALPC  ;  B5BE52, CDD_SALPK  ;
DR   B4TNP0, CDD_SALSV  ;  Q8Z5A8, CDD_SALTI  ;  Q8ZNM0, CDD_SALTY  ;
DR   Q09190, CDD_SCHPO  ;  A8GC32, CDD_SERP5  ;  A1S723, CDD_SHEAM  ;
DR   B8EF35, CDD_SHEB2  ;  A3D392, CDD_SHEB5  ;  A6WLY5, CDD_SHEB8  ;
DR   A9KXF0, CDD_SHEB9  ;  Q083S7, CDD_SHEFN  ;  B0TQV3, CDD_SHEHH  ;
DR   A3QDC9, CDD_SHELP  ;  Q8EDG1, CDD_SHEON  ;  A8H5H1, CDD_SHEPA  ;
DR   A4Y5R0, CDD_SHEPC  ;  B8CR83, CDD_SHEPW  ;  A0KYD1, CDD_SHESA  ;
DR   A8FWK2, CDD_SHESH  ;  Q0HHI5, CDD_SHESM  ;  Q0HTT9, CDD_SHESR  ;
DR   A1RL10, CDD_SHESW  ;  B1KRC5, CDD_SHEWM  ;  B2TVV2, CDD_SHIB3  ;
DR   Q322V3, CDD_SHIBS  ;  Q32EM3, CDD_SHIDS  ;  Q0T2Y0, CDD_SHIF8  ;
DR   P0ABF7, CDD_SHIFL  ;  Q3Z062, CDD_SHISS  ;  Q2NUD2, CDD_SODGM  ;
DR   A5F1V7, CDD_VIBC3  ;  Q9KSM5, CDD_VIBCH  ;  C3LLS7, CDD_VIBCM  ;
DR   Q5E4R6, CDD_VIBF1  ;  B5FEN2, CDD_VIBFM  ;  A7MVH6, CDD_VIBHB  ;
DR   Q87Q52, CDD_VIBPA  ;  B7VPF1, CDD_VIBSL  ;  Q8DA31, CDD_VIBVU  ;
DR   Q7MK48, CDD_VIBVY  ;  Q06549, CDD_YEAST  ;  A7FJK3, CDD_YERP3  ;
DR   Q1C9U7, CDD_YERPA  ;  B2JZJ6, CDD_YERPB  ;  Q8ZG08, CDD_YERPE  ;
DR   A9R1B9, CDD_YERPG  ;  Q1CGT5, CDD_YERPN  ;  A4TKN7, CDD_YERPP  ;
DR   Q66C79, CDD_YERPS  ;  B1JPZ5, CDD_YERPY  ;
//
ID   3.5.4.6
DE   AMP deaminase.
AN   5-AMP deaminase.
AN   Adenylate deaminase.
AN   Adenylic acid deaminase.
AN   AMP aminase.
AN   AMP aminohydrolase.
AN   Myoadenylate deaminase.
CA   AMP + H(2)O = IMP + NH(3).
CC   -!- Cf. EC 3.5.4.17.
PR   PROSITE; PDOC00419;
DR   P81073, AMPD1_CHICK;  P23109, AMPD1_HUMAN;  Q3V1D3, AMPD1_MOUSE;
DR   P81072, AMPD1_RABIT;  P10759, AMPD1_RAT  ;  Q01433, AMPD2_HUMAN;
DR   Q9DBT5, AMPD2_MOUSE;  Q02356, AMPD2_RAT  ;  Q01432, AMPD3_HUMAN;
DR   O08739, AMPD3_MOUSE;  O09178, AMPD3_RAT  ;  O80452, AMPD_ARATH ;
DR   Q54DD0, AMPD_DICDI ;  Q84NP7, AMPD_ORYSJ ;  P50998, AMPD_SCHPO ;
DR   P15274, AMPD_YEAST ;
//
ID   3.5.4.7
DE   ADP deaminase.
CA   ADP + H(2)O = IDP + NH(3).
//
ID   3.5.4.8
DE   Aminoimidazolase.
AN   4-aminoimidazole deaminase.
CA   4-aminoimidazole + H(2)O = imidazol-4-one + NH(3).
CF   Fe(2+).
CC   -!- Forms part of the xanthine-degradation pathway in some bacteria.
CC   -!- The product of the reaction, imidazol-4-one, can be converted non-
CC       enzymically into formiminoglycine.
//
ID   3.5.4.9
DE   Methenyltetrahydrofolate cyclohydrolase.
CA   5,10-methenyltetrahydrofolate + H(2)O = 10-formyltetrahydrofolate.
PR   PROSITE; PDOC00616;
DR   O96553, C1TC_DROME ;  P11586, C1TC_HUMAN ;  Q922D8, C1TC_MOUSE ;
DR   Q5R8P0, C1TC_PONAB ;  P27653, C1TC_RAT   ;  Q8WZJ7, C1TC_SCHPO ;
DR   Q27772, C1TC_SPOFR ;  P07245, C1TC_YEAST ;  O43007, C1TM_SCHPO ;
DR   P09440, C1TM_YEAST ;  Q49135, FCHA_METEA ;  Q6F9E6, FOLD1_ACIAD;
DR   A1R228, FOLD1_ARTAT;  Q7WAC0, FOLD1_BORPA;  Q7VZC8, FOLD1_BORPE;
DR   Q47ZE0, FOLD1_COLP3;  Q1J118, FOLD1_DEIGD;  Q24ZZ6, FOLD1_DESHY;
DR   Q0RNE2, FOLD1_FRAAA;  Q2JCX4, FOLD1_FRASC;  Q39Z32, FOLD1_GEOMG;
DR   Q74GN1, FOLD1_GEOSL;  Q5V3D9, FOLD1_HALMA;  Q74J95, FOLD1_LACJO;
DR   Q1DA76, FOLD1_MYXXD;  A1SED2, FOLD1_NOCSJ;  A1B5A7, FOLD1_PARDP;
DR   Q48KZ8, FOLD1_PSE14;  A4XTZ3, FOLD1_PSEMY;  B0KJG3, FOLD1_PSEPG;
DR   Q88LI7, FOLD1_PSEPK;  Q87YR0, FOLD1_PSESM;  Q4ZVN1, FOLD1_PSEU2;
DR   Q2KCC6, FOLD1_RHIEC;  Q989A7, FOLD1_RHILO;  Q92T88, FOLD1_RHIME;
DR   Q0SFQ8, FOLD1_RHOSR;  Q167Y9, FOLD1_ROSDO;  Q1AXT3, FOLD1_RUBXD;
DR   A4FI92, FOLD1_SACEN;  A8LWI0, FOLD1_SALAI;  A4X776, FOLD1_SALTO;
DR   Q5LNV2, FOLD1_SILPO;  A6U669, FOLD1_SINMW;  A5V4U1, FOLD1_SPHWW;
DR   Q82QG3, FOLD1_STRAW;  Q0AZF5, FOLD1_SYNWW;  Q31HQ4, FOLD1_THICR;
DR   Q6F8N7, FOLD2_ACIAD;  A1R451, FOLD2_ARTAT;  Q7W4Z7, FOLD2_BORPA;
DR   Q7VVW3, FOLD2_BORPE;  Q47XL6, FOLD2_COLP3;  Q1J0I3, FOLD2_DEIGD;
DR   Q24UZ7, FOLD2_DESHY;  Q0RI14, FOLD2_FRAAA;  Q2J9L3, FOLD2_FRASC;
DR   Q39WH4, FOLD2_GEOMG;  Q74EU7, FOLD2_GEOSL;  Q5V630, FOLD2_HALMA;
DR   Q74IM0, FOLD2_LACJO;  Q1D7Y2, FOLD2_MYXXD;  A1SMP7, FOLD2_NOCSJ;
DR   A1BBS1, FOLD2_PARDP;  Q48HJ1, FOLD2_PSE14;  A4XXZ2, FOLD2_PSEMY;
DR   B0KLM9, FOLD2_PSEPG;  Q88KM5, FOLD2_PSEPK;  Q883B5, FOLD2_PSESM;
DR   Q4ZUA4, FOLD2_PSEU2;  Q2JZV0, FOLD2_RHIEC;  Q987T6, FOLD2_RHILO;
DR   Q92RY3, FOLD2_RHIME;  Q0S375, FOLD2_RHOSR;  Q160C1, FOLD2_ROSDO;
DR   Q1AVQ0, FOLD2_RUBXD;  A4FP42, FOLD2_SACEN;  A8M449, FOLD2_SALAI;
DR   A4XBC7, FOLD2_SALTO;  Q5LT54, FOLD2_SILPO;  A6UB98, FOLD2_SINMW;
DR   A5V807, FOLD2_SPHWW;  Q82HR6, FOLD2_STRAW;  Q0AWX5, FOLD2_SYNWW;
DR   Q31FY5, FOLD2_THICR;  A4XY05, FOLD3_PSEMY;  Q160C0, FOLD3_ROSDO;
DR   Q1AT41, FOLD3_RUBXD;  A5VAA8, FOLD3_SPHWW;  B0C3J3, FOLD_ACAM1 ;
DR   A9NE96, FOLD_ACHLI ;  A1TPZ6, FOLD_ACIAC ;  Q1II76, FOLD_ACIBL ;
DR   A3M846, FOLD_ACIBT ;  A0LRU9, FOLD_ACIC1 ;  C1F683, FOLD_ACIC5 ;
DR   A5G1W5, FOLD_ACICJ ;  B9MIU6, FOLD_ACIET ;  B7JBX9, FOLD_ACIF2 ;
DR   B5EJA0, FOLD_ACIF5 ;  A1W7S2, FOLD_ACISJ ;  A3N0Q7, FOLD_ACTP2 ;
DR   B3GXP3, FOLD_ACTP7 ;  B0BPI2, FOLD_ACTPJ ;  A6VMD8, FOLD_ACTSZ ;
DR   A0KJD4, FOLD_AERHH ;  A4SNM0, FOLD_AERS4 ;  Q8UHU0, FOLD_AGRT5 ;
DR   B2UM17, FOLD_AKKM8 ;  Q0VQ92, FOLD_ALCBS ;  Q0AB42, FOLD_ALHEH ;
DR   B6EIM4, FOLD_ALISL ;  A6TPR4, FOLD_ALKMQ ;  A8MKZ5, FOLD_ALKOO ;
DR   B4RV70, FOLD_ALTMD ;  B3ESU1, FOLD_AMOA5 ;  Q2IQE1, FOLD_ANADE ;
DR   A7HDC5, FOLD_ANADF ;  Q5PBL6, FOLD_ANAMM ;  Q2GLF2, FOLD_ANAPZ ;
DR   Q3M9M0, FOLD_ANAVT ;  B7GHF9, FOLD_ANOFW ;  O67736, FOLD_AQUAE ;
DR   A8ESH8, FOLD_ARCB4 ;  Q5P922, FOLD_AROAE ;  Q9AGP6, FOLD_ARTGO ;
DR   A0JTZ0, FOLD_ARTS2 ;  A8I5P5, FOLD_AZOC5 ;  B6YRQ9, FOLD_AZOPC ;
DR   A1K589, FOLD_AZOSB ;  C1DHE7, FOLD_AZOVD ;  A7Z6J9, FOLD_BACA2 ;
DR   C3P7W0, FOLD_BACAA ;  C3LJV5, FOLD_BACAC ;  A0RIH3, FOLD_BACAH ;
DR   Q81M50, FOLD_BACAN ;  B7JM32, FOLD_BACC0 ;  Q731B2, FOLD_BACC1 ;
DR   B7IXH2, FOLD_BACC2 ;  C1ERQ4, FOLD_BACC3 ;  B7HB52, FOLD_BACC4 ;
DR   B7HNU4, FOLD_BACC7 ;  A7GSJ9, FOLD_BACCN ;  B9IXH4, FOLD_BACCQ ;
DR   Q818R5, FOLD_BACCR ;  Q635A3, FOLD_BACCZ ;  Q5LAX0, FOLD_BACFN ;
DR   Q64RB7, FOLD_BACFR ;  Q9K966, FOLD_BACHD ;  Q6HDY4, FOLD_BACHK ;
DR   Q65HI8, FOLD_BACLD ;  A8FF15, FOLD_BACP2 ;  Q5WCI9, FOLD_BACSK ;
DR   P54382, FOLD_BACSU ;  Q8A7B8, FOLD_BACTN ;  A6L2G2, FOLD_BACV8 ;
DR   A9VGW3, FOLD_BACWK ;  A1URL6, FOLD_BARBK ;  Q6G4F1, FOLD_BARHE ;
DR   Q6G0I9, FOLD_BARQU ;  A9IQD2, FOLD_BART1 ;  Q1LTX1, FOLD_BAUCH ;
DR   Q6MI74, FOLD_BDEBA ;  B8DUV2, FOLD_BIFA0 ;  A1A171, FOLD_BIFAA ;
DR   B3DSS3, FOLD_BIFLD ;  Q8G5L6, FOLD_BIFLO ;  B7GT00, FOLD_BIFLS ;
DR   Q7VRB3, FOLD_BLOFL ;  Q493A0, FOLD_BLOPB ;  Q2L1G0, FOLD_BORA1 ;
DR   Q0SPD8, FOLD_BORAP ;  Q7WJG1, FOLD_BORBR ;  O51057, FOLD_BORBU ;
DR   B7J0W5, FOLD_BORBZ ;  Q662Y6, FOLD_BORGA ;  A9ISZ5, FOLD_BORPD ;
DR   C0R292, FOLD_BRAHW ;  Q89WX9, FOLD_BRAJA ;  A5E8S0, FOLD_BRASB ;
DR   A4YK09, FOLD_BRASO ;  C0ZC05, FOLD_BREBN ;  B2SAP4, FOLD_BRUA1 ;
DR   Q2YL33, FOLD_BRUA2 ;  Q578R0, FOLD_BRUAB ;  A9MC67, FOLD_BRUC2 ;
DR   C0RLT3, FOLD_BRUMB ;  Q8YCL8, FOLD_BRUME ;  A5VV73, FOLD_BRUO2 ;
DR   A9WZ75, FOLD_BRUSI ;  Q8FVP6, FOLD_BRUSU ;  P57557, FOLD_BUCAI ;
DR   Q8K979, FOLD_BUCAP ;  Q89A92, FOLD_BUCBP ;  Q057D7, FOLD_BUCCC ;
DR   B1YT42, FOLD_BURA4 ;  Q1BHV3, FOLD_BURCA ;  B1JV19, FOLD_BURCC ;
DR   A0K8R4, FOLD_BURCH ;  B4EDU1, FOLD_BURCJ ;  Q0BDP0, FOLD_BURCM ;
DR   A9AGS9, FOLD_BURM1 ;  A3MLB7, FOLD_BURM7 ;  A2SAQ8, FOLD_BURM9 ;
DR   Q62IX5, FOLD_BURMA ;  A1V5P2, FOLD_BURMS ;  A3NX53, FOLD_BURP0 ;
DR   Q3JQL8, FOLD_BURP1 ;  A3NBC0, FOLD_BURP6 ;  B2T5N8, FOLD_BURPP ;
DR   Q63SL6, FOLD_BURPS ;  Q39ES6, FOLD_BURS3 ;  Q2SXF8, FOLD_BURTA ;
DR   A4JG19, FOLD_BURVG ;  Q13WX0, FOLD_BURXL ;  A4XLE0, FOLD_CALS8 ;
DR   A7ZCH3, FOLD_CAMC1 ;  A7GXK2, FOLD_CAMC5 ;  A0RQ49, FOLD_CAMFF ;
DR   A7I254, FOLD_CAMHC ;  A8FLR4, FOLD_CAMJ8 ;  A7H3N3, FOLD_CAMJD ;
DR   Q0PA35, FOLD_CAMJE ;  A1VZJ8, FOLD_CAMJJ ;  Q5HUU1, FOLD_CAMJR ;
DR   Q3AAY6, FOLD_CARHZ ;  B8H4A3, FOLD_CAUCN ;  Q9A8Y0, FOLD_CAUCR ;
DR   B0T3F7, FOLD_CAUSK ;  B3PHG5, FOLD_CELJU ;  A0RTU3, FOLD_CENSY ;
DR   A9WJ10, FOLD_CHLAA ;  Q5L644, FOLD_CHLAB ;  B8GC39, FOLD_CHLAD ;
DR   Q3ASI0, FOLD_CHLCH ;  Q823G2, FOLD_CHLCV ;  Q254F7, FOLD_CHLFF ;
DR   B3ECA6, FOLD_CHLL2 ;  Q9PKW1, FOLD_CHLMU ;  B3EJG9, FOLD_CHLPB ;
DR   A1BF67, FOLD_CHLPD ;  Q9Z8K3, FOLD_CHLPN ;  B9LD23, FOLD_CHLSY ;
DR   B0B9I6, FOLD_CHLT2 ;  B3QUL4, FOLD_CHLT3 ;  Q3KMU3, FOLD_CHLTA ;
DR   B0BB65, FOLD_CHLTB ;  O84081, FOLD_CHLTR ;  Q1QVV9, FOLD_CHRSD ;
DR   Q7NWQ6, FOLD_CHRVO ;  A8AJS4, FOLD_CITK8 ;  A5CU17, FOLD_CLAM3 ;
DR   B0RDR2, FOLD_CLAMS ;  Q97HC9, FOLD_CLOAB ;  A7FT56, FOLD_CLOB1 ;
DR   C3KT80, FOLD_CLOB6 ;  A6LU44, FOLD_CLOB8 ;  B2V4R7, FOLD_CLOBA ;
DR   B2TRN5, FOLD_CLOBB ;  A5I112, FOLD_CLOBH ;  C1FKP7, FOLD_CLOBJ ;
DR   B1IIW9, FOLD_CLOBK ;  A7GCL0, FOLD_CLOBL ;  B1KZC8, FOLD_CLOBM ;
DR   B8I761, FOLD_CLOCE ;  Q189R8, FOLD_CLOD6 ;  A5N5B5, FOLD_CLOK5 ;
DR   A0Q0A0, FOLD_CLONN ;  Q0TPD4, FOLD_CLOP1 ;  Q8XJD7, FOLD_CLOPE ;
DR   A9KLS3, FOLD_CLOPH ;  Q0SS01, FOLD_CLOPS ;  Q894G6, FOLD_CLOTE ;
DR   A3DEE6, FOLD_CLOTH ;  B5Y9D1, FOLD_COPPD ;  C3PLA3, FOLD_CORA7 ;
DR   Q6NIZ6, FOLD_CORDI ;  Q8FRU9, FOLD_COREF ;  A4QBY8, FOLD_CORGB ;
DR   Q8NSM0, FOLD_CORGL ;  Q4JTI3, FOLD_CORJK ;  B6J5U6, FOLD_COXB1 ;
DR   B6J1Z2, FOLD_COXB2 ;  A9KGQ5, FOLD_COXBN ;  A9NB47, FOLD_COXBR ;
DR   Q83EK7, FOLD_COXBU ;  Q0KBW5, FOLD_CUPNH ;  Q472L4, FOLD_CUPPJ ;
DR   B3R4L6, FOLD_CUPTR ;  B1WRW8, FOLD_CYAA5 ;  B8HXS0, FOLD_CYAP4 ;
DR   B7KEP3, FOLD_CYAP7 ;  B7JVV5, FOLD_CYAP8 ;  Q11UD1, FOLD_CYTH3 ;
DR   Q47IX6, FOLD_DECAR ;  Q3Z8K6, FOLD_DEHE1 ;  A5FRF1, FOLD_DEHSB ;
DR   Q3ZX43, FOLD_DEHSC ;  Q9RW02, FOLD_DEIRA ;  A9BWT7, FOLD_DELAS ;
DR   B8FLE5, FOLD_DESAA ;  C6BSL6, FOLD_DESAD ;  C0QAY0, FOLD_DESAH ;
DR   B8J466, FOLD_DESDA ;  Q316P9, FOLD_DESDG ;  C4XLR8, FOLD_DESMR ;
DR   A8ZTQ4, FOLD_DESOH ;  Q6ALZ5, FOLD_DESPS ;  A4J3F5, FOLD_DESRM ;
DR   Q72F91, FOLD_DESVH ;  B8DMA9, FOLD_DESVM ;  A1VGV4, FOLD_DESVV ;
DR   A5EX57, FOLD_DICNV ;  B5YA73, FOLD_DICT6 ;  B8E335, FOLD_DICTD ;
DR   A8LIR3, FOLD_DINSH ;  A7ZIT8, FOLD_ECO24 ;  B7UKK6, FOLD_ECO27 ;
DR   B7ME52, FOLD_ECO45 ;  B7L7F6, FOLD_ECO55 ;  Q8XCT6, FOLD_ECO57 ;
DR   B5YPP4, FOLD_ECO5E ;  B7NL23, FOLD_ECO7I ;  B7MRJ2, FOLD_ECO81 ;
DR   B7M4N2, FOLD_ECO8A ;  C4ZUX7, FOLD_ECOBW ;  B1XGC7, FOLD_ECODH ;
DR   A7ZXI3, FOLD_ECOHS ;  A1A8J4, FOLD_ECOK1 ;  Q0TKB2, FOLD_ECOL5 ;
DR   Q8FK41, FOLD_ECOL6 ;  B1IZ72, FOLD_ECOLC ;  P24186, FOLD_ECOLI ;
DR   B7N983, FOLD_ECOLU ;  B6I0H4, FOLD_ECOSE ;  B1LKE8, FOLD_ECOSM ;
DR   Q1RF04, FOLD_ECOUT ;  C5B8V3, FOLD_EDWI9 ;  Q3YRE3, FOLD_EHRCJ ;
DR   Q2GHD8, FOLD_EHRCR ;  Q5FG00, FOLD_EHRRG ;  Q5HAK8, FOLD_EHRRW ;
DR   B2KB67, FOLD_ELUMP ;  A4W7J0, FOLD_ENT38 ;  Q836W7, FOLD_ENTFA ;
DR   A7MJZ6, FOLD_ENTS8 ;  Q6D2E6, FOLD_ERWCT ;  B2VBD1, FOLD_ERWT9 ;
DR   Q2N7E3, FOLD_ERYLH ;  B7LJI7, FOLD_ESCF3 ;  C4ZBG7, FOLD_EUBR3 ;
DR   B1YLQ1, FOLD_EXIS2 ;  C4L3F6, FOLD_EXISA ;  A7HMQ2, FOLD_FERNB ;
DR   A5FNE3, FOLD_FLAJ1 ;  A6GZM5, FOLD_FLAPJ ;  B0U009, FOLD_FRAP2 ;
DR   A8L893, FOLD_FRASN ;  Q14HV5, FOLD_FRAT1 ;  A7NA91, FOLD_FRATF ;
DR   Q2A535, FOLD_FRATH ;  B2SF67, FOLD_FRATM ;  A0Q505, FOLD_FRATN ;
DR   Q0BNF1, FOLD_FRATO ;  Q5NGF3, FOLD_FRATT ;  A4IYR4, FOLD_FRATW ;
DR   Q8RDM4, FOLD_FUSNN ;  Q75TC1, FOLD_GEOKA ;  B9M769, FOLD_GEOSF ;
DR   A4IQS0, FOLD_GEOTN ;  A5GAM5, FOLD_GEOUR ;  Q7NJE8, FOLD_GLOVI ;
DR   A9HEL1, FOLD_GLUDA ;  Q5FST0, FOLD_GLUOX ;  A0M554, FOLD_GRAFK ;
DR   Q7VM86, FOLD_HAEDU ;  Q4QMI7, FOLD_HAEI8 ;  A5UAS4, FOLD_HAEIE ;
DR   A5UHL4, FOLD_HAEIG ;  P44313, FOLD_HAEIN ;  B8F605, FOLD_HAEPS ;
DR   Q0I3S5, FOLD_HAES1 ;  B0USU2, FOLD_HAES2 ;  Q2SK39, FOLD_HAHCH ;
DR   A1WUN4, FOLD_HALHL ;  B8D2H8, FOLD_HALOH ;  Q9HPY4, FOLD_HALSA ;
DR   Q18GK1, FOLD_HALWD ;  C4K7E4, FOLD_HAMD5 ;  Q17W13, FOLD_HELAH ;
DR   Q7VGF6, FOLD_HELHP ;  B0TFC9, FOLD_HELMI ;  Q1CTU9, FOLD_HELPH ;
DR   Q9ZLQ4, FOLD_HELPJ ;  P56467, FOLD_HELPY ;  A9AZP9, FOLD_HERA2 ;
DR   A4G352, FOLD_HERAR ;  B4U8W9, FOLD_HYDS0 ;  Q0BX67, FOLD_HYPNA ;
DR   Q5QWH6, FOLD_IDILO ;  A6SVR5, FOLD_JANMA ;  Q28TR2, FOLD_JANSC ;
DR   A6WF54, FOLD_KINRD ;  B5Y0K4, FOLD_KLEP3 ;  A6T5R4, FOLD_KLEP7 ;
DR   B2GM30, FOLD_KOCRD ;  C5CI88, FOLD_KOSOT ;  Q5FJG5, FOLD_LACAC ;
DR   Q03RR1, FOLD_LACBA ;  Q038F9, FOLD_LACC3 ;  B3WEY4, FOLD_LACCB ;
DR   Q1G9H1, FOLD_LACDA ;  Q049N0, FOLD_LACDB ;  B2GD67, FOLD_LACF3 ;
DR   Q044I0, FOLD_LACGA ;  A8YVX0, FOLD_LACH4 ;  Q9CH85, FOLD_LACLA ;
DR   A2RLU5, FOLD_LACLM ;  Q030A3, FOLD_LACLS ;  Q88WM8, FOLD_LACPL ;
DR   A5VKR7, FOLD_LACRD ;  B2G850, FOLD_LACRJ ;  Q1WUJ3, FOLD_LACS1 ;
DR   Q38XU9, FOLD_LACSS ;  C1D5X9, FOLD_LARHH ;  Q1MPZ8, FOLD_LAWIP ;
DR   Q5X5Q9, FOLD_LEGPA ;  A5IBF0, FOLD_LEGPC ;  Q5ZVZ1, FOLD_LEGPH ;
DR   Q5WX38, FOLD_LEGPL ;  Q6ADF1, FOLD_LEIXX ;  B0S8U6, FOLD_LEPBA ;
DR   Q04SB2, FOLD_LEPBJ ;  Q050D8, FOLD_LEPBL ;  B0SRN4, FOLD_LEPBP ;
DR   Q72QT3, FOLD_LEPIC ;  Q8F523, FOLD_LEPIN ;  B1N044, FOLD_LEUCK ;
DR   Q03YZ6, FOLD_LEUMM ;  Q92BZ4, FOLD_LISIN ;  C1L2R6, FOLD_LISMC ;
DR   Q71ZW2, FOLD_LISMF ;  B8DFW8, FOLD_LISMH ;  Q8Y7C5, FOLD_LISMO ;
DR   A0AIG1, FOLD_LISW6 ;  B1HRX9, FOLD_LYSSC ;  B9EAY2, FOLD_MACCJ ;
DR   Q2VYZ7, FOLD_MAGSA ;  A0LE04, FOLD_MAGSM ;  Q65RF1, FOLD_MANSM ;
DR   A1U1Q5, FOLD_MARAV ;  Q0ATP0, FOLD_MARMM ;  A6W1T1, FOLD_MARMS ;
DR   Q6F1V0, FOLD_MESFL ;  Q11M18, FOLD_MESSB ;  Q8TK95, FOLD_METAC ;
DR   A7IAE1, FOLD_METB6 ;  Q46A53, FOLD_METBF ;  Q12V26, FOLD_METBU ;
DR   Q9X7F6, FOLD_METC4 ;  Q1GXE6, FOLD_METFK ;  Q2FR55, FOLD_METHJ ;
DR   Q8PZQ1, FOLD_METMA ;  A3CWL0, FOLD_METMJ ;  B8GG34, FOLD_METPE ;
DR   A2SHP8, FOLD_METPP ;  A0B8J7, FOLD_METTP ;  B0JUP8, FOLD_MICAN ;
DR   C5C958, FOLD_MICLC ;  Q2RIB4, FOLD_MOOTA ;  A0QKM1, FOLD_MYCA1 ;
DR   B3PMJ8, FOLD_MYCA5 ;  B1MG21, FOLD_MYCA9 ;  Q7TWN0, FOLD_MYCBO ;
DR   A1KP49, FOLD_MYCBP ;  C1AHH2, FOLD_MYCBT ;  Q2SRE7, FOLD_MYCCT ;
DR   Q6RX33, FOLD_MYCFO ;  Q7NAE4, FOLD_MYCGA ;  P47259, FOLD_MYCGE ;
DR   A4TET2, FOLD_MYCGI ;  B8ZUV4, FOLD_MYCLB ;  O32879, FOLD_MYCLE ;
DR   B2HDR8, FOLD_MYCMM ;  Q6KID0, FOLD_MYCMO ;  Q6MSL3, FOLD_MYCMS ;
DR   Q73UA5, FOLD_MYCPA ;  Q8EV80, FOLD_MYCPE ;  P75096, FOLD_MYCPN ;
DR   Q98QV3, FOLD_MYCPU ;  A0QSY5, FOLD_MYCS2 ;  Q4A6B1, FOLD_MYCS5 ;
DR   A3PVV6, FOLD_MYCSJ ;  A1UC75, FOLD_MYCSK ;  Q1BCR8, FOLD_MYCSS ;
DR   A5U830, FOLD_MYCTA ;  O50385, FOLD_MYCTU ;  A0PNP3, FOLD_MYCUA ;
DR   A1T5D0, FOLD_MYCVP ;  Q3IRX3, FOLD_NATPD ;  B2A532, FOLD_NATTJ ;
DR   B9L952, FOLD_NAUPA ;  Q5F5D0, FOLD_NEIG1 ;  B4RQN5, FOLD_NEIG2 ;
DR   A9M068, FOLD_NEIM0 ;  Q9JWI9, FOLD_NEIMA ;  P0C277, FOLD_NEIMB ;
DR   A1KWF4, FOLD_NEIMF ;  Q2GCV3, FOLD_NEOSM ;  Q0AFN2, FOLD_NITEC ;
DR   Q82XC3, FOLD_NITEU ;  Q1QQJ9, FOLD_NITHX ;  A9A4N5, FOLD_NITMS ;
DR   Q2YC56, FOLD_NITMU ;  Q3J8Z0, FOLD_NITOC ;  A6Q2W6, FOLD_NITSB ;
DR   Q3SVE4, FOLD_NITWN ;  Q5YU63, FOLD_NOCFA ;  B2J442, FOLD_NOSP7 ;
DR   Q8Z086, FOLD_NOSS1 ;  Q2G338, FOLD_NOVAD ;  Q8EQ43, FOLD_OCEIH ;
DR   A6X610, FOLD_OCHA4 ;  Q04FB7, FOLD_OENOB ;  B6JAU5, FOLD_OLICO ;
DR   B1ZYH0, FOLD_OPITP ;  A5CF58, FOLD_ORITB ;  B3CTT4, FOLD_ORITI ;
DR   A6L8J2, FOLD_PARD8 ;  A7HSV9, FOLD_PARL1 ;  Q6MAH4, FOLD_PARUW ;
DR   Q9CJR1, FOLD_PASMU ;  C6DAX0, FOLD_PECCP ;  Q03FZ5, FOLD_PEDPA ;
DR   Q3A1Q7, FOLD_PELCD ;  Q3B4E2, FOLD_PELLD ;  B4SGR4, FOLD_PELPB ;
DR   A1AL91, FOLD_PELPD ;  A5D323, FOLD_PELTS ;  Q4FNW1, FOLD_PELUB ;
DR   A9BIV9, FOLD_PETMO ;  B4RE11, FOLD_PHEZH ;  Q7MZH1, FOLD_PHOLL ;
DR   P51696, FOLD_PHOPO ;  Q6LNV7, FOLD_PHOPR ;  Q6L046, FOLD_PICTO ;
DR   A1VN60, FOLD_POLNA ;  B1XUA6, FOLD_POLNS ;  Q12A51, FOLD_POLSJ ;
DR   A4SWT5, FOLD_POLSQ ;  Q7MVE9, FOLD_PORGI ;  B4S820, FOLD_PROA2 ;
DR   Q6A6Z2, FOLD_PROAC ;  A3PDH3, FOLD_PROM0 ;  A2C3L3, FOLD_PROM1 ;
DR   A8G5D8, FOLD_PROM2 ;  A2C873, FOLD_PROM3 ;  A9BB39, FOLD_PROM4 ;
DR   A2BX55, FOLD_PROM5 ;  Q31AF6, FOLD_PROM9 ;  Q7TVA3, FOLD_PROMA ;
DR   B4F1G5, FOLD_PROMH ;  Q7TUV8, FOLD_PROMM ;  Q7TU81, FOLD_PROMP ;
DR   A2BRP7, FOLD_PROMS ;  Q46K05, FOLD_PROMT ;  A4SER8, FOLD_PROVI ;
DR   Q15R43, FOLD_PSEA6 ;  A6V726, FOLD_PSEA7 ;  B7VB83, FOLD_PSEA8 ;
DR   Q02KT7, FOLD_PSEAB ;  Q9I2U6, FOLD_PSEAE ;  Q1ICB3, FOLD_PSEE4 ;
DR   Q4K9J4, FOLD_PSEF5 ;  Q3IF52, FOLD_PSEHT ;  A5W638, FOLD_PSEP1 ;
DR   Q3K9W7, FOLD_PSEPF ;  B1J675, FOLD_PSEPW ;  A4VL74, FOLD_PSEU5 ;
DR   Q4FTX6, FOLD_PSYA2 ;  Q1QD30, FOLD_PSYCK ;  A1SUX5, FOLD_PSYIN ;
DR   A5WGG4, FOLD_PSYWF ;  Q8ZZK1, FOLD_PYRAE ;  A4WMX1, FOLD_PYRAR ;
DR   A3MXE6, FOLD_PYRCJ ;  A1RQQ5, FOLD_PYRIL ;  Q1LP48, FOLD_RALME ;
DR   B2UFY4, FOLD_RALPJ ;  Q8XZ10, FOLD_RALSO ;  A9WM40, FOLD_RENSM ;
DR   Q1MLB6, FOLD_RHIL3 ;  Q93E15, FOLD_RHILT ;  Q6W210, FOLD_RHISN ;
DR   Q7UNN9, FOLD_RHOBA ;  O68031, FOLD_RHOCB ;  B6IVC0, FOLD_RHOCS ;
DR   Q21WC0, FOLD_RHOFD ;  Q2J3Z0, FOLD_RHOP2 ;  Q07VM6, FOLD_RHOP5 ;
DR   Q6NCQ6, FOLD_RHOPA ;  Q21D98, FOLD_RHOPB ;  Q13DA7, FOLD_RHOPS ;
DR   B3QA91, FOLD_RHOPT ;  Q2RWY4, FOLD_RHORT ;  A3PM50, FOLD_RHOS1 ;
DR   Q3J049, FOLD_RHOS4 ;  A4WQ13, FOLD_RHOS5 ;  B9KLK2, FOLD_RHOSK ;
DR   C3PNI9, FOLD_RICAE ;  A8GNK0, FOLD_RICAH ;  A8GW74, FOLD_RICB8 ;
DR   Q1RHV0, FOLD_RICBR ;  A8EYV5, FOLD_RICCK ;  Q92HY4, FOLD_RICCN ;
DR   Q4ULM3, FOLD_RICFE ;  A8F1N1, FOLD_RICM5 ;  Q9ZD32, FOLD_RICPR ;
DR   C4K0H2, FOLD_RICPU ;  B0BXN7, FOLD_RICRO ;  A8GS71, FOLD_RICRS ;
DR   Q68WL9, FOLD_RICTY ;  A7NHA9, FOLD_ROSCS ;  A5V1H2, FOLD_ROSS1 ;
DR   A1AXA0, FOLD_RUTMC ;  Q21JE9, FOLD_SACD2 ;  B5EYE2, FOLD_SALA4 ;
DR   A9MLA4, FOLD_SALAR ;  Q57S24, FOLD_SALCH ;  B5FLQ2, FOLD_SALDC ;
DR   B5QUV5, FOLD_SALEP ;  B5R6X5, FOLD_SALG2 ;  B4TA94, FOLD_SALHS ;
DR   B4SXP7, FOLD_SALNS ;  Q5PCE5, FOLD_SALPA ;  A9MW26, FOLD_SALPB ;
DR   C0PVJ3, FOLD_SALPC ;  B5BCZ5, FOLD_SALPK ;  Q2S1I0, FOLD_SALRD ;
DR   B4TN64, FOLD_SALSV ;  Q60006, FOLD_SALTI ;  P58688, FOLD_SALTY ;
DR   A8GAY2, FOLD_SERP5 ;  A1S4X3, FOLD_SHEAM ;  B8E5F1, FOLD_SHEB2 ;
DR   A3D303, FOLD_SHEB5 ;  A6WLP9, FOLD_SHEB8 ;  A9KWH5, FOLD_SHEB9 ;
DR   Q12L99, FOLD_SHEDO ;  Q07ZX6, FOLD_SHEFN ;  B0TLV1, FOLD_SHEHH ;
DR   A3QFX8, FOLD_SHELP ;  Q8EG21, FOLD_SHEON ;  A8H616, FOLD_SHEPA ;
DR   A4Y5I0, FOLD_SHEPC ;  B8CRF9, FOLD_SHEPW ;  A0KYM1, FOLD_SHESA ;
DR   A8FTH7, FOLD_SHESH ;  Q0HH99, FOLD_SHESM ;  Q0HTK5, FOLD_SHESR ;
DR   A1RL91, FOLD_SHESW ;  B1KLT9, FOLD_SHEWM ;  B2TTB0, FOLD_SHIB3 ;
DR   Q324Y6, FOLD_SHIBS ;  Q32JK7, FOLD_SHIDS ;  Q0T773, FOLD_SHIF8 ;
DR   Q83SC8, FOLD_SHIFL ;  Q3Z4P8, FOLD_SHISS ;  Q1GE28, FOLD_SILST ;
DR   Q2NV44, FOLD_SODGM ;  Q01X76, FOLD_SOLUE ;  A9GW22, FOLD_SORC5 ;
DR   Q1GNH1, FOLD_SPHAL ;  Q8KN38, FOLD_SPHCR ;  Q14NV1, FOLD_SPICI ;
DR   A7X0V3, FOLD_STAA1 ;  A6U0N1, FOLD_STAA2 ;  Q2FI15, FOLD_STAA3 ;
DR   Q2FZJ6, FOLD_STAA8 ;  A5IRV0, FOLD_STAA9 ;  Q2YX11, FOLD_STAAB ;
DR   Q5HH21, FOLD_STAAC ;  A6QFS2, FOLD_STAAE ;  Q99V34, FOLD_STAAM ;
DR   Q7A697, FOLD_STAAN ;  Q6GI21, FOLD_STAAR ;  Q6GAF0, FOLD_STAAS ;
DR   A8Z1K5, FOLD_STAAT ;  Q8NX95, FOLD_STAAW ;  B9DQ45, FOLD_STACT ;
DR   Q5HQA7, FOLD_STAEQ ;  Q8CPP4, FOLD_STAES ;  Q4L572, FOLD_STAHJ ;
DR   Q49WI7, FOLD_STAS1 ;  Q3K2M6, FOLD_STRA1 ;  Q8E6M3, FOLD_STRA3 ;
DR   Q8E168, FOLD_STRA5 ;  Q9K3J6, FOLD_STRCO ;  C0M7V0, FOLD_STRE4 ;
DR   B4U1W4, FOLD_STREM ;  A8AW32, FOLD_STRGC ;  B1W3N7, FOLD_STRGG ;
DR   Q8DVC1, FOLD_STRMU ;  Q99YX2, FOLD_STRP1 ;  Q04L84, FOLD_STRP2 ;
DR   P0DF88, FOLD_STRP3 ;  Q5XB24, FOLD_STRP6 ;  Q7CN13, FOLD_STRP8 ;
DR   Q1JAV4, FOLD_STRPB ;  Q1JL04, FOLD_STRPC ;  Q1JG29, FOLD_STRPD ;
DR   Q1J5U5, FOLD_STRPF ;  A2RDM9, FOLD_STRPG ;  Q48SM7, FOLD_STRPM ;
DR   Q97RI9, FOLD_STRPN ;  P0DF89, FOLD_STRPQ ;  B5XM84, FOLD_STRPZ ;
DR   Q8DQD3, FOLD_STRR6 ;  A4VZV9, FOLD_STRS2 ;  C0MD36, FOLD_STRS7 ;
DR   A3CLQ4, FOLD_STRSV ;  A4VTM4, FOLD_STRSY ;  Q5M0P7, FOLD_STRT1 ;
DR   Q5M583, FOLD_STRT2 ;  Q03LK0, FOLD_STRTD ;  P96050, FOLD_STRTR ;
DR   B9DUU0, FOLD_STRU0 ;  Q30RJ0, FOLD_SULDN ;  A6Q815, FOLD_SULNB ;
DR   B2V9R3, FOLD_SULSY ;  Q67NB1, FOLD_SYMTH ;  Q2LUP9, FOLD_SYNAS ;
DR   Q31Q60, FOLD_SYNE7 ;  A0LLR2, FOLD_SYNFM ;  Q2JT84, FOLD_SYNJA ;
DR   Q2JQ25, FOLD_SYNJB ;  Q5N421, FOLD_SYNP6 ;  A5GM31, FOLD_SYNPW ;
DR   Q7TTW4, FOLD_SYNPX ;  A5GRZ3, FOLD_SYNR3 ;  Q0IBG9, FOLD_SYNS3 ;
DR   Q3AYX2, FOLD_SYNS9 ;  Q3AIB3, FOLD_SYNSC ;  Q55626, FOLD_SYNY3 ;
DR   C5BI30, FOLD_TERTT ;  B7IF42, FOLD_THEAB ;  Q05213, FOLD_THEAC ;
DR   Q8DMU0, FOLD_THEEB ;  Q47LR8, FOLD_THEFY ;  A8F7D6, FOLD_THELT ;
DR   A6LP88, FOLD_THEM4 ;  Q9X288, FOLD_THEMA ;  B1YBM2, FOLD_THENV ;
DR   A5ILJ9, FOLD_THEP1 ;  B9KZ23, FOLD_THERP ;  B1LAQ6, FOLD_THESQ ;
DR   Q72JL7, FOLD_THET2 ;  Q5SJ94, FOLD_THET8 ;  Q8RAD0, FOLD_THETN ;
DR   Q979W3, FOLD_THEVO ;  B5YJV1, FOLD_THEYD ;  Q3SKX9, FOLD_THIDA ;
DR   B8GNT6, FOLD_THISH ;  C4LG01, FOLD_TOLAT ;  Q73RS2, FOLD_TREDE ;
DR   O83714, FOLD_TREPA ;  B2S3X1, FOLD_TREPS ;  Q10X46, FOLD_TRIEI ;
DR   Q83HF0, FOLD_TROW8 ;  Q83FS2, FOLD_TROWT ;  C5CXD8, FOLD_VARPS ;
DR   A1WJ68, FOLD_VEREI ;  A5CVZ6, FOLD_VESOH ;  A5F6V4, FOLD_VIBC3 ;
DR   Q9KQQ6, FOLD_VIBCH ;  Q5E3Y1, FOLD_VIBF1 ;  B5FG69, FOLD_VIBFM ;
DR   A7MT09, FOLD_VIBHB ;  Q87RB8, FOLD_VIBPA ;  B7VL71, FOLD_VIBSL ;
DR   Q8DB06, FOLD_VIBVU ;  Q7MIX2, FOLD_VIBVY ;  Q8D2W0, FOLD_WIGBR ;
DR   Q73HK3, FOLD_WOLPM ;  B3CLT4, FOLD_WOLPP ;  Q7M8X1, FOLD_WOLSU ;
DR   Q5GTK9, FOLD_WOLTR ;  C0R2N7, FOLD_WOLWR ;  Q8PK86, FOLD_XANAC ;
DR   Q3BSP5, FOLD_XANC5 ;  Q4UVC7, FOLD_XANC8 ;  B0RSB3, FOLD_XANCB ;
DR   Q8P8Q4, FOLD_XANCP ;  Q2P3R1, FOLD_XANOM ;  B2SLG3, FOLD_XANOP ;
DR   Q5H0S4, FOLD_XANOR ;  Q9PAR4, FOLD_XYLFA ;  Q87BK4, FOLD_XYLFT ;
DR   A1JNX2, FOLD_YERE8 ;  A7FL44, FOLD_YERP3 ;  Q1C4U4, FOLD_YERPA ;
DR   B2K7N4, FOLD_YERPB ;  Q7CJY7, FOLD_YERPE ;  A9R256, FOLD_YERPG ;
DR   Q1CKX8, FOLD_YERPN ;  A4TP60, FOLD_YERPP ;  Q66DK7, FOLD_YERPS ;
DR   B1JHI9, FOLD_YERPY ;  Q5NP22, FOLD_ZYMMO ;  Q9H903, MTD2L_HUMAN;
DR   Q0P5C2, MTDC_BOVIN ;  Q5ZKA5, MTDC_CHICK ;  Q04448, MTDC_DROME ;
DR   P13995, MTDC_HUMAN ;  P18155, MTDC_MOUSE ;
//
ID   3.5.4.10
DE   IMP cyclohydrolase.
AN   IMP synthetase.
AN   Inosinicase.
CA   IMP + H(2)O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.
DR   P54113, PUR91_YEAST;  P38009, PUR92_YEAST;  B0BZH9, PUR9_ACAM1 ;
DR   A5FUH4, PUR9_ACICJ ;  B7J5P7, PUR9_ACIF2 ;  B5EL42, PUR9_ACIF5 ;
DR   A0KGJ2, PUR9_AERHH ;  A4SR98, PUR9_AERS4 ;  B9JEU9, PUR9_AGRRK ;
DR   Q8UBM8, PUR9_AGRT5 ;  Q0VMY5, PUR9_ALCBS ;  B6ENA8, PUR9_ALISL ;
DR   A6TLS7, PUR9_ALKMQ ;  A8MLI9, PUR9_ALKOO ;  Q46480, PUR9_ALLVD ;
DR   B4S133, PUR9_ALTMD ;  B8JHC9, PUR9_ANAD2 ;  Q2IKQ7, PUR9_ANADE ;
DR   A7HA60, PUR9_ANADF ;  B4UJ61, PUR9_ANASK ;  B9MS89, PUR9_ANATD ;
DR   Q3M6G3, PUR9_ANAVT ;  B7GFU2, PUR9_ANOFW ;  O67775, PUR9_AQUAE ;
DR   C1DLJ1, PUR9_AZOVD ;  C3PBN4, PUR9_BACAA ;  C3L536, PUR9_BACAC ;
DR   A0R900, PUR9_BACAH ;  Q81ZG8, PUR9_BACAN ;  B7JM89, PUR9_BACC0 ;
DR   Q73EN1, PUR9_BACC1 ;  B7IUV7, PUR9_BACC2 ;  C1EV67, PUR9_BACC3 ;
DR   B7H4U0, PUR9_BACC4 ;  B7HS36, PUR9_BACC7 ;  A7GKI2, PUR9_BACCN ;
DR   B9J1K9, PUR9_BACCQ ;  Q81IP9, PUR9_BACCR ;  Q63GS9, PUR9_BACCZ ;
DR   Q9KF53, PUR9_BACHD ;  Q6HPA0, PUR9_BACHK ;  Q5WJ82, PUR9_BACSK ;
DR   P12048, PUR9_BACSU ;  Q8A155, PUR9_BACTN ;  A9VRF5, PUR9_BACWK ;
DR   A1UR09, PUR9_BARBK ;  Q6G5S5, PUR9_BARHE ;  Q6FYG4, PUR9_BARQU ;
DR   A9IZD0, PUR9_BART1 ;  Q1LU51, PUR9_BAUCH ;  B3DRY6, PUR9_BIFLD ;
DR   Q8G6B1, PUR9_BIFLO ;  Q0VCK0, PUR9_BOVIN ;  C0QXU6, PUR9_BRAHW ;
DR   Q89WU7, PUR9_BRAJA ;  B2S7P0, PUR9_BRUA1 ;  Q2YLH0, PUR9_BRUA2 ;
DR   Q57B71, PUR9_BRUAB ;  A9M854, PUR9_BRUC2 ;  C0RF67, PUR9_BRUMB ;
DR   P67539, PUR9_BRUME ;  A5VSF8, PUR9_BRUO2 ;  A9WWU1, PUR9_BRUSI ;
DR   P67540, PUR9_BRUSU ;  B8D8J3, PUR9_BUCA5 ;  P57143, PUR9_BUCAI ;
DR   Q8KA70, PUR9_BUCAP ;  B8D6U7, PUR9_BUCAT ;  Q89B23, PUR9_BUCBP ;
DR   B1YTE2, PUR9_BURA4 ;  Q1BZ33, PUR9_BURCA ;  B1JVV6, PUR9_BURCC ;
DR   A0K4L7, PUR9_BURCH ;  B4EES4, PUR9_BURCJ ;  Q0BI80, PUR9_BURCM ;
DR   A9AH70, PUR9_BURM1 ;  A3MP76, PUR9_BURM7 ;  A2S597, PUR9_BURM9 ;
DR   Q62HA6, PUR9_BURMA ;  A1V068, PUR9_BURMS ;  A3NZ64, PUR9_BURP0 ;
DR   Q3JNS8, PUR9_BURP1 ;  A3NDF2, PUR9_BURP6 ;  B2JGU1, PUR9_BURP8 ;
DR   B2SYJ7, PUR9_BURPP ;  Q63QX8, PUR9_BURPS ;  Q39JI8, PUR9_BURS3 ;
DR   Q2SZ52, PUR9_BURTA ;  A4JBL5, PUR9_BURVG ;  Q13UC4, PUR9_BURXL ;
DR   A4XKZ2, PUR9_CALS8 ;  A7ZCZ7, PUR9_CAMC1 ;  A7GYY6, PUR9_CAMC5 ;
DR   A8FM07, PUR9_CAMJ8 ;  A7H375, PUR9_CAMJD ;  Q9PNY2, PUR9_CAMJE ;
DR   A1VZU4, PUR9_CAMJJ ;  Q5HUK6, PUR9_CAMJR ;  Q9ABY4, PUR9_CAUCR ;
DR   P31335, PUR9_CHICK ;  A9WEK8, PUR9_CHLAA ;  Q3ATZ1, PUR9_CHLCH ;
DR   B3EEI0, PUR9_CHLL2 ;  B3QQA5, PUR9_CHLP8 ;  B3ELV3, PUR9_CHLPB ;
DR   A1BE85, PUR9_CHLPD ;  B3QS62, PUR9_CHLT3 ;  Q8KFK6, PUR9_CHLTE ;
DR   Q7P0M1, PUR9_CHRVO ;  A8AKS0, PUR9_CITK8 ;  Q97J91, PUR9_CLOAB ;
DR   A7FXD3, PUR9_CLOB1 ;  C3L2U9, PUR9_CLOB6 ;  A6LSB3, PUR9_CLOB8 ;
DR   B2V3C3, PUR9_CLOBA ;  B2TN76, PUR9_CLOBB ;  A5I5V9, PUR9_CLOBH ;
DR   C1FV76, PUR9_CLOBJ ;  B1IL57, PUR9_CLOBK ;  A7GH96, PUR9_CLOBL ;
DR   B1KZ55, PUR9_CLOBM ;  B8I490, PUR9_CLOCE ;  Q18CW0, PUR9_CLOD6 ;
DR   B9E4K6, PUR9_CLOK1 ;  A5N0Q0, PUR9_CLOK5 ;  A0Q1J0, PUR9_CLONN ;
DR   Q0TTB0, PUR9_CLOP1 ;  Q8XMK2, PUR9_CLOPE ;  Q0SV48, PUR9_CLOPS ;
DR   Q892X3, PUR9_CLOTE ;  A3DEU9, PUR9_CLOTH ;  Q489F4, PUR9_COLP3 ;
DR   C3PF03, PUR9_CORA7 ;  Q9RHX6, PUR9_CORAM ;  Q6NID8, PUR9_CORDI ;
DR   Q8FR29, PUR9_COREF ;  A4QCK4, PUR9_CORGB ;  Q8NS21, PUR9_CORGL ;
DR   Q0KEC0, PUR9_CUPNH ;  Q475R4, PUR9_CUPPJ ;  B2AH76, PUR9_CUPTR ;
DR   B8HPG4, PUR9_CYAP4 ;  B7KGS0, PUR9_CYAP7 ;  B7K3N8, PUR9_CYAP8 ;
DR   C1CWJ7, PUR9_DEIDV ;  Q1J119, PUR9_DEIGD ;  Q9RW01, PUR9_DEIRA ;
DR   B8FP05, PUR9_DESHD ;  Q24QH6, PUR9_DESHY ;  Q86L14, PUR9_DICDI ;
DR   A8LMD0, PUR9_DINSH ;  A7ZUM3, PUR9_ECO24 ;  B7UPG1, PUR9_ECO27 ;
DR   B7MIZ2, PUR9_ECO45 ;  B7LAV3, PUR9_ECO55 ;  Q8X611, PUR9_ECO57 ;
DR   B5Z0A3, PUR9_ECO5E ;  B7NRT9, PUR9_ECO7I ;  B7MRD0, PUR9_ECO81 ;
DR   B7M7R5, PUR9_ECO8A ;  C5A0U7, PUR9_ECOBW ;  B1XC09, PUR9_ECODH ;
DR   A8A7A6, PUR9_ECOHS ;  A1AIH7, PUR9_ECOK1 ;  Q0TA59, PUR9_ECOL5 ;
DR   Q8FB68, PUR9_ECOL6 ;  B1IUP1, PUR9_ECOLC ;  P15639, PUR9_ECOLI ;
DR   B7NFU7, PUR9_ECOLU ;  B6I5L8, PUR9_ECOSE ;  B1LPG6, PUR9_ECOSM ;
DR   Q1R5X1, PUR9_ECOUT ;  B2KCF7, PUR9_ELUMP ;  Q833Z3, PUR9_ENTFA ;
DR   A7MJ89, PUR9_ENTS8 ;  Q6DAL2, PUR9_ERWCT ;  B2VG81, PUR9_ERWT9 ;
DR   B7LUJ6, PUR9_ESCF3 ;  Q8REV6, PUR9_FUSNN ;  B5EBF9, PUR9_GEOBB ;
DR   B3E7F6, PUR9_GEOLS ;  Q39RK1, PUR9_GEOMG ;  B9M4Q6, PUR9_GEOSF ;
DR   Q74FJ9, PUR9_GEOSL ;  C6E5Z3, PUR9_GEOSM ;  A5G879, PUR9_GEOUR ;
DR   P43852, PUR9_HAEIN ;  Q0I557, PUR9_HAES1 ;  B0UWT1, PUR9_HAES2 ;
DR   B0TEC5, PUR9_HELMI ;  A4G1U6, PUR9_HERAR ;  P31939, PUR9_HUMAN ;
DR   A6SUQ1, PUR9_JANMA ;  Q28K03, PUR9_JANSC ;  B5XYD2, PUR9_KLEP3 ;
DR   A6TGR3, PUR9_KLEP7 ;  Q5FIV5, PUR9_LACAC ;  Q037V3, PUR9_LACC3 ;
DR   B3WF93, PUR9_LACCB ;  Q1G9G2, PUR9_LACDA ;  Q049M1, PUR9_LACDB ;
DR   Q9CFG0, PUR9_LACLA ;  A2RJY0, PUR9_LACLM ;  Q02Y66, PUR9_LACLS ;
DR   Q88U29, PUR9_LACPL ;  A5VHU2, PUR9_LACRD ;  B2G5C2, PUR9_LACRJ ;
DR   Q1WU55, PUR9_LACS1 ;  Q38XW3, PUR9_LACSS ;  C1D6F1, PUR9_LARHH ;
DR   Q6AD62, PUR9_LEIXX ;  B0SGW3, PUR9_LEPBA ;  Q04T56, PUR9_LEPBJ ;
DR   Q051H8, PUR9_LEPBL ;  B0SQ10, PUR9_LEPBP ;  Q72RT5, PUR9_LEPIC ;
DR   Q8F3W6, PUR9_LEPIN ;  B1MY42, PUR9_LEUCK ;  Q03Y85, PUR9_LEUMM ;
DR   Q92AP3, PUR9_LISIN ;  C1KW64, PUR9_LISMC ;  Q71YQ3, PUR9_LISMF ;
DR   B8DDZ2, PUR9_LISMH ;  Q8Y6C5, PUR9_LISMO ;  A0AJL9, PUR9_LISW6 ;
DR   B1HTV8, PUR9_LYSSC ;  B9EAZ2, PUR9_MACCJ ;  A0LDB0, PUR9_MAGSM ;
DR   Q11CT4, PUR9_MESSB ;  Q1H4G7, PUR9_METFK ;  B0JL55, PUR9_MICAN ;
DR   Q2RGU9, PUR9_MOOTA ;  Q9CWJ9, PUR9_MOUSE ;  P67542, PUR9_MYCBO ;
DR   A1KH91, PUR9_MYCBP ;  C1ALU3, PUR9_MYCBT ;  B8ZU05, PUR9_MYCLB ;
DR   Q9Z5H5, PUR9_MYCLE ;  B2HEC3, PUR9_MYCMM ;  Q9RAJ5, PUR9_MYCPA ;
DR   A3Q5N7, PUR9_MYCSJ ;  A1UL88, PUR9_MYCSK ;  Q1B3W0, PUR9_MYCSS ;
DR   A5U0Z7, PUR9_MYCTA ;  P67541, PUR9_MYCTU ;  A0PWC5, PUR9_MYCUA ;
DR   Q1D898, PUR9_MYXXD ;  B2A5W1, PUR9_NATTJ ;  Q5F6T1, PUR9_NEIG1 ;
DR   B4RP71, PUR9_NEIG2 ;  A9M4I2, PUR9_NEIM0 ;  Q9JUQ8, PUR9_NEIMA ;
DR   Q9JZM7, PUR9_NEIMB ;  A1KTP9, PUR9_NEIMF ;  Q3JC90, PUR9_NITOC ;
DR   A1SMP8, PUR9_NOCSJ ;  B2IX54, PUR9_NOSP7 ;  Q8YSJ2, PUR9_NOSS1 ;
DR   Q8CXK7, PUR9_OCEIH ;  A6WXV3, PUR9_OCHA4 ;  Q04EU6, PUR9_OENOB ;
DR   A1B5K8, PUR9_PARDP ;  A7HSQ6, PUR9_PARL1 ;  P57828, PUR9_PASMU ;
DR   C6DHT5, PUR9_PECCP ;  Q03E83, PUR9_PEDPA ;  Q3A2D6, PUR9_PELCD ;
DR   Q3B5R1, PUR9_PELLD ;  B4SDT6, PUR9_PELPB ;  A1AS76, PUR9_PELPD ;
DR   C0QRH2, PUR9_PERMH ;  A9BIX9, PUR9_PETMO ;  Q7N954, PUR9_PHOLL ;
DR   B1XS23, PUR9_POLNS ;  A4T025, PUR9_POLSQ ;  Q5R5C2, PUR9_PONAB ;
DR   B4S3H9, PUR9_PROA2 ;  Q6A6Y8, PUR9_PROAC ;  A3PAY7, PUR9_PROM0 ;
DR   A2C098, PUR9_PROM1 ;  A8G2S6, PUR9_PROM2 ;  A2CCK6, PUR9_PROM3 ;
DR   A9BDN8, PUR9_PROM4 ;  A2BUP7, PUR9_PROM5 ;  Q31CR6, PUR9_PROM9 ;
DR   Q7VDS0, PUR9_PROMA ;  B4EYT2, PUR9_PROMH ;  Q7TUM7, PUR9_PROMM ;
DR   Q7TUG1, PUR9_PROMP ;  A2BP65, PUR9_PROMS ;  Q46HA8, PUR9_PROMT ;
DR   A4SDE6, PUR9_PROVI ;  A6VCW0, PUR9_PSEA7 ;  B7V1R6, PUR9_PSEA8 ;
DR   Q02FG6, PUR9_PSEAB ;  Q9HUV9, PUR9_PSEAE ;  Q1I4C1, PUR9_PSEE4 ;
DR   Q4KIX5, PUR9_PSEF5 ;  C3K6E0, PUR9_PSEFS ;  Q3IIC3, PUR9_PSEHT ;
DR   A4XQ60, PUR9_PSEMY ;  A5W9K7, PUR9_PSEP1 ;  B0KJZ6, PUR9_PSEPG ;
DR   Q88DK3, PUR9_PSEPK ;  B1J5T3, PUR9_PSEPW ;  Q87VR9, PUR9_PSESM ;
DR   A4VPK9, PUR9_PSEU5 ;  Q4FRN8, PUR9_PSYA2 ;  Q1QA75, PUR9_PSYCK ;
DR   A1SZJ2, PUR9_PSYIN ;  A5WFX4, PUR9_PSYWF ;  Q1LRB3, PUR9_RALME ;
DR   B2UFL5, PUR9_RALPJ ;  Q8Y232, PUR9_RALSO ;  O35567, PUR9_RAT   ;
DR   B3PS36, PUR9_RHIE6 ;  Q2K2T6, PUR9_RHIEC ;  Q1MA35, PUR9_RHIL3 ;
DR   Q98ES7, PUR9_RHILO ;  B5ZV31, PUR9_RHILW ;  Q92KX6, PUR9_RHIME ;
DR   C3MAR5, PUR9_RHISN ;  Q7UKJ8, PUR9_RHOBA ;  Q2RN46, PUR9_RHORT ;
DR   A3PNE9, PUR9_RHOS1 ;  Q3IYU8, PUR9_RHOS4 ;  A4WWQ0, PUR9_RHOS5 ;
DR   B9KP36, PUR9_RHOSK ;  Q16CE0, PUR9_ROSDO ;  B5F1I9, PUR9_SALA4 ;
DR   A9MHC3, PUR9_SALAR ;  B5FQM1, PUR9_SALDC ;  B5QYG1, PUR9_SALEP ;
DR   B5RFH8, PUR9_SALG2 ;  B4TDF3, PUR9_SALHS ;  B4T108, PUR9_SALNS ;
DR   Q5PKA9, PUR9_SALPA ;  A9N0L8, PUR9_SALPB ;  C0Q2T8, PUR9_SALPC ;
DR   B5BJS5, PUR9_SALPK ;  B4TQL6, PUR9_SALSV ;  Q8Z335, PUR9_SALTI ;
DR   P26978, PUR9_SALTY ;  O74928, PUR9_SCHPO ;  A8G8G3, PUR9_SERP5 ;
DR   A1S2J9, PUR9_SHEAM ;  Q12IP4, PUR9_SHEDO ;  Q088G0, PUR9_SHEFN ;
DR   B0TR91, PUR9_SHEHH ;  A3QII0, PUR9_SHELP ;  Q8EJM1, PUR9_SHEON ;
DR   A8GZM3, PUR9_SHEPA ;  B8CTW4, PUR9_SHEPW ;  A8FQD4, PUR9_SHESH ;
DR   B1KNA0, PUR9_SHEWM ;  B2TWJ3, PUR9_SHIB3 ;  Q31TZ1, PUR9_SHIBS ;
DR   Q32AH9, PUR9_SHIDS ;  Q0SXZ4, PUR9_SHIF8 ;  Q83IR9, PUR9_SHIFL ;
DR   Q3YUX8, PUR9_SHISS ;  Q5LN38, PUR9_SILPO ;  Q1GKJ2, PUR9_SILST ;
DR   A6UED3, PUR9_SINMW ;  Q2NWQ7, PUR9_SODGM ;  A9GIT1, PUR9_SORC5 ;
DR   A6U0P1, PUR9_STAA2 ;  Q2FI05, PUR9_STAA3 ;  Q2FZI6, PUR9_STAA8 ;
DR   A5IRW0, PUR9_STAA9 ;  Q2YX50, PUR9_STAAB ;  Q5HH11, PUR9_STAAC ;
DR   A6QFT1, PUR9_STAAE ;  P67543, PUR9_STAAM ;  P67544, PUR9_STAAN ;
DR   Q6GI11, PUR9_STAAR ;  Q6GAE0, PUR9_STAAS ;  Q8NX88, PUR9_STAAW ;
DR   B9DQ42, PUR9_STACT ;  Q5HQ97, PUR9_STAEQ ;  Q8CT27, PUR9_STAES ;
DR   Q4L582, PUR9_STAHJ ;  Q49WJ7, PUR9_STAS1 ;  Q3K3Z7, PUR9_STRA1 ;
DR   P67545, PUR9_STRA3 ;  P67546, PUR9_STRA5 ;  Q9KY50, PUR9_STRCO ;
DR   C0MB61, PUR9_STRE4 ;  A8AUA2, PUR9_STRGC ;  B4SL92, PUR9_STRM5 ;
DR   B2FJP9, PUR9_STRMK ;  Q8DWK8, PUR9_STRMU ;  Q04N19, PUR9_STRP2 ;
DR   P0DD60, PUR9_STRP3 ;  B5E5J9, PUR9_STRP4 ;  Q5XEF2, PUR9_STRP6 ;
DR   C1C9V4, PUR9_STRP7 ;  Q8P310, PUR9_STRP8 ;  Q1JE78, PUR9_STRPB ;
DR   Q1JP34, PUR9_STRPC ;  Q1JJ80, PUR9_STRPD ;  Q1J934, PUR9_STRPF ;
DR   B1I7V8, PUR9_STRPI ;  B8ZJN3, PUR9_STRPJ ;  Q48VY9, PUR9_STRPM ;
DR   Q97T99, PUR9_STRPN ;  P0DD61, PUR9_STRPQ ;  B5XJ20, PUR9_STRPZ ;
DR   Q8DRM1, PUR9_STRR6 ;  A4VYK5, PUR9_STRS2 ;  C0MC89, PUR9_STRS7 ;
DR   Q9F1T4, PUR9_STRSU ;  A4VSB5, PUR9_STRSY ;  Q03MZ6, PUR9_STRTD ;
DR   B9DSR6, PUR9_STRU0 ;  C1CBM7, PUR9_STRZJ ;  C1CHW2, PUR9_STRZP ;
DR   C1CNS9, PUR9_STRZT ;  Q67KG3, PUR9_SYMTH ;  Q31R91, PUR9_SYNE7 ;
DR   A5GIF4, PUR9_SYNPW ;  Q7TTX6, PUR9_SYNPX ;  Q0IDE8, PUR9_SYNS3 ;
DR   Q3B083, PUR9_SYNS9 ;  Q3AN13, PUR9_SYNSC ;  Q0AW31, PUR9_SYNWW ;
DR   P74741, PUR9_SYNY3 ;  Q8DIN5, PUR9_THEEB ;  Q9X0X6, PUR9_THEMA ;
DR   B0KBQ1, PUR9_THEP3 ;  B0K3Q8, PUR9_THEPX ;  Q8RC55, PUR9_THETN ;
DR   B5YLE5, PUR9_THEYD ;  Q31II8, PUR9_THICR ;  C4LA41, PUR9_TOLAT ;
DR   Q116T4, PUR9_TRIEI ;  C5CL84, PUR9_VARPS ;  A5F3U8, PUR9_VIBC3 ;
DR   Q9KV80, PUR9_VIBCH ;  C3LQN2, PUR9_VIBCM ;  Q5E257, PUR9_VIBF1 ;
DR   B5FC70, PUR9_VIBFM ;  A7MXG0, PUR9_VIBHB ;  Q87KT0, PUR9_VIBPA ;
DR   B7VM57, PUR9_VIBSL ;  Q8DD06, PUR9_VIBVU ;  Q7MGT5, PUR9_VIBVY ;
DR   Q8D244, PUR9_WIGBR ;  Q8PQ19, PUR9_XANAC ;  Q3BY85, PUR9_XANC5 ;
DR   Q4UZD2, PUR9_XANC8 ;  B0RN27, PUR9_XANCB ;  Q8PD47, PUR9_XANCP ;
DR   Q2P866, PUR9_XANOM ;  B2SRB2, PUR9_XANOP ;  Q5H5H7, PUR9_XANOR ;
DR   B2I4L7, PUR9_XYLF2 ;  Q9PC10, PUR9_XYLFA ;  B0U7A0, PUR9_XYLFM ;
DR   Q87D58, PUR9_XYLFT ;  A1JIJ7, PUR9_YERE8 ;  A7FNG6, PUR9_YERP3 ;
DR   Q1C1V9, PUR9_YERPA ;  B2K130, PUR9_YERPB ;  Q8ZAR3, PUR9_YERPE ;
DR   A9R8E1, PUR9_YERPG ;  Q1CN60, PUR9_YERPN ;  A4TS14, PUR9_YERPP ;
DR   Q66FN5, PUR9_YERPS ;  B1JJL6, PUR9_YERPY ;  B9LU81, PURO_HALLT ;
DR   Q5UZ65, PURO_HALMA ;  B0R7Q4, PURO_HALS3 ;  Q9HMV4, PURO_HALSA ;
DR   Q18DI6, PURO_HALWD ;  A6UV34, PURO_META3 ;  Q58043, PURO_METJA ;
DR   Q8TZ52, PURO_METKA ;  A4FWM4, PURO_METM5 ;  A9AA03, PURO_METM6 ;
DR   A6VGP7, PURO_METM7 ;  Q6LXN9, PURO_METMP ;  A5ULV3, PURO_METS3 ;
DR   Q2NEI3, PURO_METST ;  O27099, PURO_METTH ;  A0B9N7, PURO_METTP ;
DR   A6UPV4, PURO_METVS ;  Q3ITS6, PURO_NATPD ;  Q5JD29, PURO_PYRKO ;
DR   Q0W6S4, PURO_UNCMA ;
//
ID   3.5.4.11
DE   Pterin deaminase.
CA   2-amino-4-hydroxypteridine + H(2)O = 2,4-dihydroxypteridine + NH(3).
CC   -!- The animal enzyme is specific for pterin, isoxanthopterin and
CC       tetrahydropterin.
DR   P0CI72, IXPDE_UNKP ;
//
ID   3.5.4.12
DE   dCMP deaminase.
AN   Deoxycytidylate deaminase.
CA   dCMP + H(2)O = dUMP + NH(3).
CC   -!- Also acts on some 5-substituted dCMPs.
PR   PROSITE; PDOC00702;
DR   O22000, DCTD_BPMD2 ;  P00814, DCTD_BPT2  ;  P16006, DCTD_BPT4  ;
DR   P30648, DCTD_CAEEL ;  Q9VWA2, DCTD_DROME ;  P32321, DCTD_HUMAN ;
DR   Q8K2D6, DCTD_MOUSE ;  Q5RC69, DCTD_PONAB ;  Q5M9G0, DCTD_RAT   ;
DR   O43012, DCTD_SCHPO ;  P06773, DCTD_YEAST ;
//
ID   3.5.4.13
DE   dCTP deaminase.
AN   Deoxycytidine triphosphate deaminase.
CA   dCTP + H(2)O = dUTP + NH(3).
DR   A1TL98, DCD_ACIAC  ;  Q6FE29, DCD_ACIAD  ;  Q02103, DCD_ACIAM  ;
DR   B7GZ86, DCD_ACIB3  ;  B7I774, DCD_ACIB5  ;  B2HUI0, DCD_ACIBC  ;
DR   Q1ISG1, DCD_ACIBL  ;  B0VU22, DCD_ACIBS  ;  A3M2T0, DCD_ACIBT  ;
DR   B0V8B3, DCD_ACIBY  ;  A0LWS4, DCD_ACIC1  ;  C1F6A5, DCD_ACIC5  ;
DR   A5FYN3, DCD_ACICJ  ;  B9MFG4, DCD_ACIET  ;  B7J7X4, DCD_ACIF2  ;
DR   B5EN98, DCD_ACIF5  ;  A1W538, DCD_ACISJ  ;  A3N0J5, DCD_ACTP2  ;
DR   B3H1H2, DCD_ACTP7  ;  B0BPB6, DCD_ACTPJ  ;  A6VMP5, DCD_ACTSZ  ;
DR   A0KKF9, DCD_AERHH  ;  Q9YFA8, DCD_AERPE  ;  A4SML2, DCD_AERS4  ;
DR   Q0VP73, DCD_ALCBS  ;  B4RZ25, DCD_ALTMD  ;  B9KHN3, DCD_ANAMF  ;
DR   Q5PBP3, DCD_ANAMM  ;  Q2GLJ4, DCD_ANAPZ  ;  O67539, DCD_AQUAE  ;
DR   Q5P236, DCD_AROAE  ;  A1RAW1, DCD_ARTAT  ;  B8H717, DCD_ARTCA  ;
DR   A1KAG0, DCD_AZOSB  ;  C1DEF6, DCD_AZOVD  ;  Q9KFV3, DCD_BACHD  ;
DR   Q1LT76, DCD_BAUCH  ;  C5C4E1, DCD_BEUC1  ;  B8DUY2, DCD_BIFA0  ;
DR   A1A3S8, DCD_BIFAA  ;  B3DP64, DCD_BIFLD  ;  Q8G478, DCD_BIFLO  ;
DR   B7GPC4, DCD_BIFLS  ;  Q2KYR0, DCD_BORA1  ;  Q7WP40, DCD_BORBR  ;
DR   Q7W1D3, DCD_BORPA  ;  A9I7R5, DCD_BORPD  ;  Q7W0F2, DCD_BORPE  ;
DR   P57209, DCD_BUCAI  ;  Q9ZHD8, DCD_BUCAP  ;  P59464, DCD_BUCBP  ;
DR   B1YUS8, DCD_BURA4  ;  Q1BUI0, DCD_BURCA  ;  B1JWR9, DCD_BURCC  ;
DR   A0K9K6, DCD_BURCH  ;  B4E8D6, DCD_BURCJ  ;  Q0BCT7, DCD_BURCM  ;
DR   A9AHK2, DCD_BURM1  ;  A3MLM0, DCD_BURM7  ;  A2SAG2, DCD_BURM9  ;
DR   Q62LD5, DCD_BURMA  ;  A1V5V5, DCD_BURMS  ;  A3NSM2, DCD_BURP0  ;
DR   A3N6Y6, DCD_BURP6  ;  B2JEP7, DCD_BURP8  ;  B2T181, DCD_BURPP  ;
DR   Q63W86, DCD_BURPS  ;  Q39DV8, DCD_BURS3  ;  Q2T083, DCD_BURTA  ;
DR   A4JGW2, DCD_BURVG  ;  Q143I2, DCD_BURXL  ;  A8MC64, DCD_CALMQ  ;
DR   A7ZFS7, DCD_CAMC1  ;  A7H0H0, DCD_CAMC5  ;  A0RR66, DCD_CAMFF  ;
DR   A7I3J2, DCD_CAMHC  ;  A8FMZ7, DCD_CAMJ8  ;  A7H291, DCD_CAMJD  ;
DR   Q9PN07, DCD_CAMJE  ;  Q5HTB5, DCD_CAMJR  ;  B9KDH6, DCD_CAMLR  ;
DR   B3PEB5, DCD_CELJU  ;  A9WHV4, DCD_CHLAA  ;  Q5L687, DCD_CHLAB  ;
DR   B8G3E6, DCD_CHLAD  ;  Q823K6, DCD_CHLCV  ;  Q254B3, DCD_CHLFF  ;
DR   Q9PKZ9, DCD_CHLMU  ;  Q9Z8F1, DCD_CHLPN  ;  B9LAF7, DCD_CHLSY  ;
DR   B0B9E6, DCD_CHLT2  ;  Q3KMY3, DCD_CHLTA  ;  B0BB25, DCD_CHLTB  ;
DR   O84042, DCD_CHLTR  ;  Q1QVP3, DCD_CHRSD  ;  Q7NS72, DCD_CHRVO  ;
DR   A8AEF5, DCD_CITK8  ;  A5CV47, DCD_CLAM3  ;  B0RD07, DCD_CLAMS  ;
DR   Q97N13, DCD_CLOAB  ;  A6M273, DCD_CLOB8  ;  B2UWE6, DCD_CLOBA  ;
DR   B2TNM9, DCD_CLOBB  ;  Q9ZNJ8, DCD_CLOHI  ;  A3DFH7, DCD_CLOTH  ;
DR   Q480H7, DCD_COLP3  ;  B5Y8K7, DCD_COPPD  ;  Q6NEW7, DCD_CORDI  ;
DR   Q8FM44, DCD_COREF  ;  A4QHN8, DCD_CORGB  ;  Q8NLT9, DCD_CORGL  ;
DR   Q4JXY1, DCD_CORJK  ;  C4LGU9, DCD_CORK4  ;  B6J4W5, DCD_COXB1  ;
DR   B6J3W2, DCD_COXB2  ;  A9KDG3, DCD_COXBN  ;  A9NA54, DCD_COXBR  ;
DR   Q83B31, DCD_COXBU  ;  Q0K7L4, DCD_CUPNH  ;  Q474W3, DCD_CUPPJ  ;
DR   B3R622, DCD_CUPTR  ;  Q11TJ6, DCD_CYTH3  ;  Q47IJ7, DCD_DECAR  ;
DR   B8D5T1, DCD_DESK1  ;  A5EVM4, DCD_DICNV  ;  B5YB40, DCD_DICT6  ;
DR   B8DYK8, DCD_DICTD  ;  A7ZNN9, DCD_ECO24  ;  B7UTA3, DCD_ECO27  ;
DR   B7ME78, DCD_ECO45  ;  B7L9T9, DCD_ECO55  ;  P63902, DCD_ECO57  ;
DR   B5YUC5, DCD_ECO5E  ;  B7NQC0, DCD_ECO7I  ;  B7MWX9, DCD_ECO81  ;
DR   B7M449, DCD_ECO8A  ;  C4ZSF3, DCD_ECOBW  ;  B1X701, DCD_ECODH  ;
DR   A8A1T7, DCD_ECOHS  ;  A1ACS1, DCD_ECOK1  ;  Q0TG25, DCD_ECOL5  ;
DR   P63901, DCD_ECOL6  ;  B1IZ09, DCD_ECOLC  ;  P28248, DCD_ECOLI  ;
DR   B7NCA1, DCD_ECOLU  ;  B6I8D6, DCD_ECOSE  ;  B1LNX6, DCD_ECOSM  ;
DR   Q1RA05, DCD_ECOUT  ;  C5BCP0, DCD_EDWI9  ;  Q3YRB6, DCD_EHRCJ  ;
DR   A4WCB5, DCD_ENT38  ;  A7MHG9, DCD_ENTS8  ;  Q6D7B3, DCD_ERWCT  ;
DR   B2VFR2, DCD_ERWT9  ;  Q2N7F4, DCD_ERYLH  ;  B7LV29, DCD_ESCF3  ;
DR   B0U0D4, DCD_FRAP2  ;  A8LDU1, DCD_FRASN  ;  Q14HL3, DCD_FRAT1  ;
DR   A7NCP9, DCD_FRATF  ;  Q2A311, DCD_FRATH  ;  B2SGM6, DCD_FRATM  ;
DR   A0Q696, DCD_FRATN  ;  Q0BLI9, DCD_FRATO  ;  Q5NG61, DCD_FRATT  ;
DR   A4IXU4, DCD_FRATW  ;  C1A8Z5, DCD_GEMAT  ;  Q5FSM1, DCD_GLUOX  ;
DR   Q0BTB7, DCD_GRABC  ;  Q7VL26, DCD_HAEDU  ;  Q4QP54, DCD_HAEI8  ;
DR   A5UB16, DCD_HAEIE  ;  A5UFT9, DCD_HAEIG  ;  P44534, DCD_HAEIN  ;
DR   B8F4U0, DCD_HAEPS  ;  Q0I2Y8, DCD_HAES1  ;  B0UT66, DCD_HAES2  ;
DR   A1WUY3, DCD_HALHL  ;  B9LSY2, DCD_HALLT  ;  Q5V1D1, DCD_HALMA  ;
DR   B8D0W3, DCD_HALOH  ;  B0R2Y7, DCD_HALS3  ;  Q9HSG3, DCD_HALSA  ;
DR   Q18KN9, DCD_HALWD  ;  C4K8I1, DCD_HAMD5  ;  Q17YF5, DCD_HELAH  ;
DR   Q7VJQ0, DCD_HELHP  ;  B6JMS3, DCD_HELP2  ;  B5Z879, DCD_HELPG  ;
DR   Q9ZKD0, DCD_HELPJ  ;  B2UUI8, DCD_HELPS  ;  O25136, DCD_HELPY  ;
DR   A9B2B7, DCD_HERA2  ;  A4G422, DCD_HERAR  ;  B4U7Y7, DCD_HYDS0  ;
DR   A2BLY5, DCD_HYPBU  ;  Q5R0F4, DCD_IDILO  ;  A8A906, DCD_IGNH4  ;
DR   A6SX77, DCD_JANMA  ;  B5XT28, DCD_KLEP3  ;  A6TBG5, DCD_KLEP7  ;
DR   B2GGA3, DCD_KOCRD  ;  B1L7R6, DCD_KORCO  ;  C1D4P1, DCD_LARHH  ;
DR   Q5X0R9, DCD_LEGPA  ;  Q5ZRC6, DCD_LEGPH  ;  Q5WSJ3, DCD_LEGPL  ;
DR   Q6AC71, DCD_LEIXX  ;  B0SH49, DCD_LEPBA  ;  Q04WA6, DCD_LEPBJ  ;
DR   Q04X69, DCD_LEPBL  ;  B0SQR4, DCD_LEPBP  ;  B1XWK4, DCD_LEPCP  ;
DR   Q72W72, DCD_LEPIC  ;  Q8F9W5, DCD_LEPIN  ;  Q2W744, DCD_MAGSA  ;
DR   Q65S72, DCD_MANSM  ;  A1TZ68, DCD_MARAV  ;  A6VVJ7, DCD_MARMS  ;
DR   A6UWW5, DCD_META3  ;  A7I6N9, DCD_METB6  ;  Q60CV1, DCD_METCA  ;
DR   Q2FQM7, DCD_METHJ  ;  B3DX06, DCD_METI4  ;  Q8TYK5, DCD_METKA  ;
DR   A2SQW1, DCD_METLZ  ;  A4FW98, DCD_METM5  ;  A9A9N7, DCD_METM6  ;
DR   A6VH12, DCD_METM7  ;  A3CTK0, DCD_METMJ  ;  Q6LXC6, DCD_METMP  ;
DR   B8GHN1, DCD_METPE  ;  A5UK79, DCD_METS3  ;  A4YD26, DCD_METS5  ;
DR   Q2NFH1, DCD_METST  ;  O27875, DCD_METTH  ;  A6UQ71, DCD_METVS  ;
DR   C5C6P4, DCD_MICLC  ;  A0QM15, DCD_MYCA1  ;  Q7U297, DCD_MYCBO  ;
DR   A1KFE4, DCD_MYCBP  ;  C1AJZ9, DCD_MYCBT  ;  A4T0X9, DCD_MYCGI  ;
DR   B8ZTC3, DCD_MYCLB  ;  Q9CB17, DCD_MYCLE  ;  B2HP20, DCD_MYCMM  ;
DR   Q73T98, DCD_MYCPA  ;  A0QQ98, DCD_MYCS2  ;  A3PTK2, DCD_MYCSJ  ;
DR   A1U9Z8, DCD_MYCSK  ;  Q1BEY3, DCD_MYCSS  ;  A5TZ48, DCD_MYCTA  ;
DR   O07247, DCD_MYCTU  ;  A0PLM7, DCD_MYCUA  ;  A1T2M8, DCD_MYCVP  ;
DR   Q74MA7, DCD_NANEQ  ;  Q3IMI4, DCD_NATPD  ;  B9L789, DCD_NAUPA  ;
DR   Q5F9H3, DCD_NEIG1  ;  B4RKC9, DCD_NEIG2  ;  A9M3Z7, DCD_NEIM0  ;
DR   P63903, DCD_NEIMA  ;  P63904, DCD_NEIMB  ;  A1KT90, DCD_NEIMF  ;
DR   Q2GCG8, DCD_NEOSM  ;  Q0AES7, DCD_NITEC  ;  Q820Q1, DCD_NITEU  ;
DR   Q2Y7L1, DCD_NITMU  ;  Q3JBW4, DCD_NITOC  ;  A6Q5J3, DCD_NITSB  ;
DR   Q5YNG0, DCD_NOCFA  ;  A1SQ24, DCD_NOCSJ  ;  Q2GC28, DCD_NOVAD  ;
DR   A5CFN1, DCD_ORITB  ;  B3CUK6, DCD_ORITI  ;  Q6MCL7, DCD_PARUW  ;
DR   P57891, DCD_PASMU  ;  C6DCI7, DCD_PECCP  ;  Q4FNE5, DCD_PELUB  ;
DR   C0QRW3, DCD_PERMH  ;  Q7N6J3, DCD_PHOLL  ;  Q12DD9, DCD_POLSJ  ;
DR   B4ESY9, DCD_PROMH  ;  Q48LT4, DCD_PSE14  ;  Q15UL9, DCD_PSEA6  ;
DR   A6V1U5, DCD_PSEA7  ;  B7UWK0, DCD_PSEA8  ;  Q02QW9, DCD_PSEAB  ;
DR   Q9HYC9, DCD_PSEAE  ;  C3K710, DCD_PSEFS  ;  Q3IL08, DCD_PSEHT  ;
DR   A4XS57, DCD_PSEMY  ;  A5VZJ1, DCD_PSEP1  ;  Q3KH11, DCD_PSEPF  ;
DR   B0KUD5, DCD_PSEPG  ;  Q88NV4, DCD_PSEPK  ;  B1J1A3, DCD_PSEPW  ;
DR   Q87XN2, DCD_PSESM  ;  Q4ZPK9, DCD_PSEU2  ;  Q4FRT5, DCD_PSYA2  ;
DR   Q1QAD8, DCD_PSYCK  ;  A1SSZ3, DCD_PSYIN  ;  A5WG49, DCD_PSYWF  ;
DR   Q9UXS8, DCD_PYRAB  ;  Q8ZW23, DCD_PYRAE  ;  A4WMK4, DCD_PYRAR  ;
DR   A3MUX9, DCD_PYRCJ  ;  Q8X251, DCD_PYRFU  ;  O57706, DCD_PYRHO  ;
DR   A1RVJ1, DCD_PYRIL  ;  Q5JH10, DCD_PYRKO  ;  Q1LJP8, DCD_RALME  ;
DR   B2UA12, DCD_RALPJ  ;  Q8XWV4, DCD_RALSO  ;  A9WT08, DCD_RENSM  ;
DR   Q7UU94, DCD_RHOBA  ;  B6INF8, DCD_RHOCS  ;  C0ZSY9, DCD_RHOE4  ;
DR   Q21TA1, DCD_RHOFD  ;  C1AWB6, DCD_RHOOB  ;  Q2RQK4, DCD_RHORT  ;
DR   Q0S5R4, DCD_RHOSR  ;  C3PMB0, DCD_RICAE  ;  A8GM16, DCD_RICAH  ;
DR   A8GUI6, DCD_RICB8  ;  Q1RGY6, DCD_RICBR  ;  A8EXD6, DCD_RICCK  ;
DR   Q92JG8, DCD_RICCN  ;  Q4UNF3, DCD_RICFE  ;  Q9ZE77, DCD_RICPR  ;
DR   C4K188, DCD_RICPU  ;  A8GQN3, DCD_RICRS  ;  Q68XU3, DCD_RICTY  ;
DR   A7NGH6, DCD_ROSCS  ;  Q21I23, DCD_SACD2  ;  B5EXU9, DCD_SALA4  ;
DR   A8LWH4, DCD_SALAI  ;  A9MKX9, DCD_SALAR  ;  Q57MN2, DCD_SALCH  ;
DR   B5FMU0, DCD_SALDC  ;  B5R0B4, DCD_SALEP  ;  B5RBW2, DCD_SALG2  ;
DR   B4T9T3, DCD_SALHS  ;  B4SX92, DCD_SALNS  ;  Q5PDX5, DCD_SALPA  ;
DR   A9N7M1, DCD_SALPB  ;  C0Q1G1, DCD_SALPC  ;  B5BF74, DCD_SALPK  ;
DR   B4TNH8, DCD_SALSV  ;  P63906, DCD_SALTI  ;  A4X0Z1, DCD_SALTO  ;
DR   P63905, DCD_SALTY  ;  A8GC41, DCD_SERP5  ;  A1S795, DCD_SHEAM  ;
DR   B8E961, DCD_SHEB2  ;  A3D5E2, DCD_SHEB5  ;  A6WP53, DCD_SHEB8  ;
DR   A9L4F3, DCD_SHEB9  ;  Q081H6, DCD_SHEFN  ;  A3QD95, DCD_SHELP  ;
DR   Q8EDX5, DCD_SHEON  ;  A4Y7K5, DCD_SHEPC  ;  A0KW27, DCD_SHESA  ;
DR   Q0HJN3, DCD_SHESM  ;  Q0HVX9, DCD_SHESR  ;  A1RIY3, DCD_SHESW  ;
DR   B2TYB7, DCD_SHIB3  ;  Q323E8, DCD_SHIBS  ;  Q32EH3, DCD_SHIDS  ;
DR   Q0T366, DCD_SHIF8  ;  Q83QZ5, DCD_SHIFL  ;  Q3Z0D8, DCD_SHISS  ;
DR   Q2NUC6, DCD_SODGM  ;  Q1GV40, DCD_SPHAL  ;  A5VDM8, DCD_SPHWW  ;
DR   A3DNG5, DCD_STAMF  ;  Q82EZ9, DCD_STRAW  ;  Q9X8W0, DCD_STRCO  ;
DR   B1VMF9, DCD_STRGG  ;  B4SQX4, DCD_STRM5  ;  B2FP14, DCD_STRMK  ;
DR   Q4JAM0, DCD_SULAC  ;  A6Q6E1, DCD_SULNB  ;  Q980T7, DCD_SULSO  ;
DR   B2V937, DCD_SULSY  ;  Q976G3, DCD_SULTO  ;  C5BNH5, DCD_TERTT  ;
DR   Q9HKK0, DCD_THEAC  ;  Q47KQ7, DCD_THEFY  ;  C5A430, DCD_THEGJ  ;
DR   B1Y8Z1, DCD_THENV  ;  B9KYK0, DCD_THERP  ;  C6A1F7, DCD_THESM  ;
DR   Q3SH29, DCD_THIDA  ;  B8GMA8, DCD_THISH  ;  C4LEX2, DCD_TOLAT  ;
DR   Q83H71, DCD_TROW8  ;  Q820X8, DCD_TROWT  ;  C5CV58, DCD_VARPS  ;
DR   Q8D218, DCD_WIGBR  ;  Q73I07, DCD_WOLPM  ;  B3CNH7, DCD_WOLPP  ;
DR   Q7M9A0, DCD_WOLSU  ;  Q5GSZ3, DCD_WOLTR  ;  C0R2R5, DCD_WOLWR  ;
DR   Q8PJ05, DCD_XANAC  ;  Q3BRJ0, DCD_XANC5  ;  Q4UWF9, DCD_XANC8  ;
DR   B0RR56, DCD_XANCB  ;  Q8P7P1, DCD_XANCP  ;  Q2P0R9, DCD_XANOM  ;
DR   B2SWC5, DCD_XANOP  ;  Q5GXN9, DCD_XANOR  ;  B2I9E4, DCD_XYLF2  ;
DR   Q9PFB6, DCD_XYLFA  ;  B0U5C4, DCD_XYLFM  ;  Q87AD1, DCD_XYLFT  ;
DR   A1JTX3, DCD_YERE8  ;  A7FJJ3, DCD_YERP3  ;  Q1C9T5, DCD_YERPA  ;
DR   B2JZK6, DCD_YERPB  ;  Q8ZFZ8, DCD_YERPE  ;  A9R2M4, DCD_YERPG  ;
DR   Q1CGU7, DCD_YERPN  ;  A4TKM6, DCD_YERPP  ;  Q66C69, DCD_YERPS  ;
DR   B1JPY5, DCD_YERPY  ;
//
ID   3.5.4.14
DE   Deoxycytidine deaminase.
CA   Deoxycytidine + H(2)O = deoxyuridine + NH(3).
//
ID   3.5.4.15
DE   Guanosine deaminase.
AN   Guanosine aminase.
CA   Guanosine + H(2)O = xanthosine + NH(3).
//
ID   3.5.4.16
DE   GTP cyclohydrolase I.
CA   GTP + H(2)O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-
CA   trihydroxypropyl)-dihydropteridine triphosphate.
CC   -!- The reaction involves hydrolysis of two C-N bonds and isomerization
CC       of the pentose unit; the recyclization may be non-enzymic.
CC   -!- Involved in the de novo synthesis of tetrahydrobiopterin from GTP,
CC       with the other enzymes involved being EC 1.1.1.153 and EC 4.2.3.12.
PR   PROSITE; PDOC00672;
DR   Q9CGE3, FOLKE_LACLA;  Q8GJP4, FOLKE_LACLM;  Q8YLL1, GCH11_NOSS1;
DR   Q9HYG8, GCH11_PSEAE;  Q88LV4, GCH11_PSEPK;  Q887V1, GCH11_PSESM;
DR   Q8YN49, GCH12_NOSS1;  Q9I351, GCH12_PSEAE;  Q88JY1, GCH12_PSEPK;
DR   Q884Q3, GCH12_PSESM;  A3N0R3, GCH1_ACTP2 ;  B3GXP9, GCH1_ACTP7 ;
DR   B0BPI8, GCH1_ACTPJ ;  A0KIN6, GCH1_AERHH ;  A4SPE8, GCH1_AERS4 ;
DR   Q8UEK8, GCH1_AGRT5 ;  B9JWF1, GCH1_AGRVS ;  Q0A939, GCH1_ALHEH ;
DR   B6EGN8, GCH1_ALISL ;  O66603, GCH1_AQUAE ;  A8HUG2, GCH1_AZOC5 ;
DR   C1DHG2, GCH1_AZOVD ;  A7Z630, GCH1_BACA2 ;  C3P598, GCH1_BACAA ;
DR   C3L8S8, GCH1_BACAC ;  A0RBW5, GCH1_BACAH ;  Q81SW2, GCH1_BACAN ;
DR   B7JGZ6, GCH1_BACC0 ;  Q73AY4, GCH1_BACC1 ;  B7IP89, GCH1_BACC2 ;
DR   C1EN08, GCH1_BACC3 ;  B7HHR5, GCH1_BACC4 ;  B7HL21, GCH1_BACC7 ;
DR   A7GN48, GCH1_BACCN ;  B9IVN3, GCH1_BACCQ ;  Q81FQ8, GCH1_BACCR ;
DR   Q63DM1, GCH1_BACCZ ;  Q5L925, GCH1_BACFN ;  Q64P85, GCH1_BACFR ;
DR   Q9KCC7, GCH1_BACHD ;  Q6HL44, GCH1_BACHK ;  A8FEL2, GCH1_BACP2 ;
DR   P48063, GCH1_BACPU ;  P19465, GCH1_BACSU ;  Q8A0U0, GCH1_BACTN ;
DR   A9VMC0, GCH1_BACWK ;  A1USJ5, GCH1_BARBK ;  Q6G3J8, GCH1_BARHE ;
DR   Q6FZZ4, GCH1_BARQU ;  Q1LT77, GCH1_BAUCH ;  B2IBC4, GCH1_BEII9 ;
DR   B3DR12, GCH1_BIFLD ;  Q8G3S1, GCH1_BIFLO ;  Q7VRX3, GCH1_BLOFL ;
DR   Q492J7, GCH1_BLOPB ;  Q89IW2, GCH1_BRAJA ;  C0ZCC7, GCH1_BREBN ;
DR   B2S5T0, GCH1_BRUA1 ;  Q2YQ03, GCH1_BRUA2 ;  Q57D61, GCH1_BRUAB ;
DR   A9M586, GCH1_BRUC2 ;  C0RJ47, GCH1_BRUMB ;  Q8YH94, GCH1_BRUME ;
DR   A5VQL0, GCH1_BRUO2 ;  B0CGM4, GCH1_BRUSI ;  Q8G0L4, GCH1_BRUSU ;
DR   Q8KA05, GCH1_BUCAP ;  Q19980, GCH1_CAEEL ;  A8MC60, GCH1_CALMQ ;
DR   A7ZB36, GCH1_CAMC1 ;  A7GW42, GCH1_CAMC5 ;  A8FJZ5, GCH1_CAMJ8 ;
DR   A7H1R1, GCH1_CAMJD ;  P51594, GCH1_CAMJE ;  A1VXS2, GCH1_CAMJJ ;
DR   Q5HWX4, GCH1_CAMJR ;  B9KDZ8, GCH1_CAMLR ;  Q3ADI2, GCH1_CARHZ ;
DR   Q9AAY3, GCH1_CAUCR ;  P50141, GCH1_CHICK ;  Q3ATN0, GCH1_CHLCH ;
DR   Q8KEA8, GCH1_CHLTE ;  Q1QV64, GCH1_CHRSD ;  Q7NYZ2, GCH1_CHRVO ;
DR   A8AE79, GCH1_CITK8 ;  Q97D54, GCH1_CLOAB ;  A7FU67, GCH1_CLOB1 ;
DR   C3KVW3, GCH1_CLOB6 ;  A6LWG6, GCH1_CLOB8 ;  A5I231, GCH1_CLOBH ;
DR   C1FN26, GCH1_CLOBJ ;  B1IL94, GCH1_CLOBK ;  A7GDP1, GCH1_CLOBL ;
DR   B1L1S1, GCH1_CLOBM ;  B8I184, GCH1_CLOCE ;  Q18BW7, GCH1_CLOD6 ;
DR   B9E092, GCH1_CLOK1 ;  A5N6S3, GCH1_CLOK5 ;  A0Q2L7, GCH1_CLONN ;
DR   Q0TRM0, GCH1_CLOP1 ;  Q8XLM2, GCH1_CLOPE ;  Q0STY9, GCH1_CLOPS ;
DR   A3DHH6, GCH1_CLOTH ;  C3PJE8, GCH1_CORA7 ;  Q8FMG3, GCH1_COREF ;
DR   A4QH94, GCH1_CORGB ;  Q8NM84, GCH1_CORGL ;  A9KFF3, GCH1_COXBN ;
DR   A9NDB3, GCH1_COXBR ;  Q83DE3, GCH1_COXBU ;  Q3Z782, GCH1_DEHE1 ;
DR   A5FQD3, GCH1_DEHSB ;  Q3ZYB5, GCH1_DEHSC ;  Q9RYB4, GCH1_DEIRA ;
DR   A4J5D0, GCH1_DESRM ;  Q94465, GCH1_DICDI ;  P48596, GCH1_DROME ;
DR   A7ZNX6, GCH1_ECO24 ;  B7UFG9, GCH1_ECO27 ;  B7MF66, GCH1_ECO45 ;
DR   B7LAH4, GCH1_ECO55 ;  P0A6T7, GCH1_ECO57 ;  B5YWU3, GCH1_ECO5E ;
DR   B7NMB8, GCH1_ECO7I ;  B7MXG6, GCH1_ECO81 ;  B7M4Z9, GCH1_ECO8A ;
DR   C4ZU03, GCH1_ECOBW ;  B1X7P1, GCH1_ECODH ;  A8A214, GCH1_ECOHS ;
DR   A1AD13, GCH1_ECOK1 ;  Q0TFT7, GCH1_ECOL5 ;  P0A6T6, GCH1_ECOL6 ;
DR   B1IYB6, GCH1_ECOLC ;  P0A6T5, GCH1_ECOLI ;  B7NCI3, GCH1_ECOLU ;
DR   B6I8K3, GCH1_ECOSE ;  B1LKQ0, GCH1_ECOSM ;  Q1R9R9, GCH1_ECOUT ;
DR   C5BCL9, GCH1_EDWI9 ;  A4WCI8, GCH1_ENT38 ;  Q82Z12, GCH1_ENTFA ;
DR   Q6D3N3, GCH1_ERWCT ;  B2VII2, GCH1_ERWT9 ;  B7LVB3, GCH1_ESCF3 ;
DR   P51597, GCH1_EUGGR ;  B0S1R1, GCH1_FINM2 ;  A5FHM7, GCH1_FLAJ1 ;
DR   Q8RH43, GCH1_FUSNN ;  Q5KXT7, GCH1_GEOKA ;  C5D3E8, GCH1_GEOSW ;
DR   Q7NK98, GCH1_GLOVI ;  Q7VM90, GCH1_HAEDU ;  Q4QKH4, GCH1_HAEI8 ;
DR   A5UC59, GCH1_HAEIE ;  A5UEW4, GCH1_HAEIG ;  P43866, GCH1_HAEIN ;
DR   Q0I3F6, GCH1_HAES1 ;  B0UUA9, GCH1_HAES2 ;  Q2SPJ2, GCH1_HAHCH ;
DR   C4K3L4, GCH1_HAMD5 ;  Q17WX5, GCH1_HELAH ;  Q7VFG4, GCH1_HELHP ;
DR   B6JME9, GCH1_HELP2 ;  B5Z7T2, GCH1_HELPG ;  Q1CSU6, GCH1_HELPH ;
DR   Q9ZKS2, GCH1_HELPJ ;  B2UU76, GCH1_HELPS ;  P56462, GCH1_HELPY ;
DR   P30793, GCH1_HUMAN ;  B4U640, GCH1_HYDS0 ;  A2BL58, GCH1_HYPBU ;
DR   Q0BXB5, GCH1_HYPNA ;  A6SZ52, GCH1_JANMA ;  B5XP57, GCH1_KLEP3 ;
DR   A6TBN8, GCH1_KLEP7 ;  Q88ST4, GCH1_LACPL ;  Q38WN0, GCH1_LACSS ;
DR   Q6ACQ1, GCH1_LEIXX ;  B0S8X8, GCH1_LEPBA ;  Q04P36, GCH1_LEPBJ ;
DR   Q056J8, GCH1_LEPBL ;  B0SRX6, GCH1_LEPBP ;  Q72LY8, GCH1_LEPIC ;
DR   Q8EYG1, GCH1_LEPIN ;  Q92A75, GCH1_LISIN ;  C1KWN3, GCH1_LISMC ;
DR   Q71Y82, GCH1_LISMF ;  B8DBZ3, GCH1_LISMH ;  Q8Y5X1, GCH1_LISMO ;
DR   A0AK45, GCH1_LISW6 ;  B1HTA3, GCH1_LYSSC ;  Q65TR0, GCH1_MANSM ;
DR   Q0AM02, GCH1_MARMM ;  Q11JM4, GCH1_MESSB ;  Q607T5, GCH1_METCA ;
DR   B0U881, GCH1_METS4 ;  Q05915, GCH1_MOUSE ;  P51598, GCH1_MUCPU ;
DR   A0QA85, GCH1_MYCA1 ;  B1MGU9, GCH1_MYCA9 ;  P64208, GCH1_MYCBO ;
DR   A1KPU4, GCH1_MYCBP ;  C1AI67, GCH1_MYCBT ;  A4T5P2, GCH1_MYCGI ;
DR   B8ZU42, GCH1_MYCLB ;  O69531, GCH1_MYCLE ;  B2HJ53, GCH1_MYCMM ;
DR   Q743Z2, GCH1_MYCPA ;  A5U8T4, GCH1_MYCTA ;  P64207, GCH1_MYCTU ;
DR   A0PV57, GCH1_MYCUA ;  A1TG42, GCH1_MYCVP ;  P51599, GCH1_NEUCR ;
DR   Q2Y6B3, GCH1_NITMU ;  B2J1L7, GCH1_NOSP7 ;  A6X0X0, GCH1_OCHA4 ;
DR   P51596, GCH1_ONCMY ;  O61573, GCH1_OSTOS ;  A6LFE8, GCH1_PARD8 ;
DR   P57865, GCH1_PASMU ;  C6DEM6, GCH1_PECCP ;  A5D2D8, GCH1_PELTS ;
DR   Q4FL89, GCH1_PELUB ;  C0QPU5, GCH1_PERMH ;  Q7N6K7, GCH1_PHOLL ;
DR   Q6LQL4, GCH1_PHOPR ;  P51600, GCH1_PHYBL ;  B2RIJ1, GCH1_PORG3 ;
DR   Q7MWI5, GCH1_PORGI ;  A4SF37, GCH1_PROVI ;  Q15YG1, GCH1_PSEA6 ;
DR   Q3IF89, GCH1_PSEHT ;  Q8ZWW5, GCH1_PYRAE ;  Q8XZK8, GCH1_RALSO ;
DR   P22288, GCH1_RAT   ;  Q98LQ6, GCH1_RHILO ;  Q92QB4, GCH1_RHIME ;
DR   C3MB45, GCH1_RHISN ;  Q7UJJ7, GCH1_RHOBA ;  Q2IY20, GCH1_RHOP2 ;
DR   Q6N4E7, GCH1_RHOPA ;  Q212N0, GCH1_RHOPB ;  Q134L7, GCH1_RHOPS ;
DR   B3QE25, GCH1_RHOPT ;  C3PNA0, GCH1_RICAE ;  A8GN89, GCH1_RICAH ;
DR   A8GUB6, GCH1_RICB8 ;  Q1RID0, GCH1_RICBR ;  Q92I93, GCH1_RICCN ;
DR   Q4ULX3, GCH1_RICFE ;  A8F1F2, GCH1_RICM5 ;  Q9ZDE8, GCH1_RICPR ;
DR   C4K2D8, GCH1_RICPU ;  B0BXB8, GCH1_RICRO ;  A8GRW0, GCH1_RICRS ;
DR   Q68WZ4, GCH1_RICTY ;  B5EYP3, GCH1_SALA4 ;  A9MK63, GCH1_SALAR ;
DR   Q57ME6, GCH1_SALCH ;  B5FNJ7, GCH1_SALDC ;  B5R163, GCH1_SALEP ;
DR   B5RC32, GCH1_SALG2 ;  B4TAL5, GCH1_SALHS ;  B4SY26, GCH1_SALNS ;
DR   Q5PE52, GCH1_SALPA ;  A9N6K0, GCH1_SALPB ;  C0Q0U7, GCH1_SALPC ;
DR   B5BE43, GCH1_SALPK ;  B4TNQ0, GCH1_SALSV ;  P64210, GCH1_SALTI ;
DR   P64209, GCH1_SALTY ;  O13774, GCH1_SCHPO ;  A8GC24, GCH1_SERP5 ;
DR   A1S2C7, GCH1_SHEAM ;  B8E4J0, GCH1_SHEB2 ;  A3CZJ1, GCH1_SHEB5 ;
DR   A6WIA1, GCH1_SHEB8 ;  A9KXZ9, GCH1_SHEB9 ;  Q12SG0, GCH1_SHEDO ;
DR   A3QIQ4, GCH1_SHELP ;  Q8E9L6, GCH1_SHEON ;  A4Y2K7, GCH1_SHEPC ;
DR   A0L1S4, GCH1_SHESA ;  Q0HE51, GCH1_SHESM ;  Q0HZU8, GCH1_SHESR ;
DR   A1REU0, GCH1_SHESW ;  B2TVT9, GCH1_SHIB3 ;  Q31YW1, GCH1_SHIBS ;
DR   Q32EN8, GCH1_SHIDS ;  Q0T2X1, GCH1_SHIF8 ;  P0A6T8, GCH1_SHIFL ;
DR   Q3Z053, GCH1_SHISS ;  A6U8C2, GCH1_SINMW ;  Q2NUE3, GCH1_SODGM ;
DR   Q3K0Y1, GCH1_STRA1 ;  Q8E549, GCH1_STRA3 ;  Q8DZI5, GCH1_STRA5 ;
DR   Q82EE8, GCH1_STRAW ;  Q9X8I3, GCH1_STRCO ;  A8AZD8, GCH1_STRGC ;
DR   B1VSG4, GCH1_STRGG ;  Q8DUG2, GCH1_STRMU ;  P0C0C2, GCH1_STRP1 ;
DR   Q04MF9, GCH1_STRP2 ;  P0DB30, GCH1_STRP3 ;  B5E6W5, GCH1_STRP4 ;
DR   Q5XCA9, GCH1_STRP6 ;  C1CB65, GCH1_STRP7 ;  P0A3E9, GCH1_STRP8 ;
DR   A2REL9, GCH1_STRPG ;  B1I918, GCH1_STRPI ;  B8ZL26, GCH1_STRPJ ;
DR   P51595, GCH1_STRPN ;  P0DB31, GCH1_STRPQ ;  B2ISL9, GCH1_STRPS ;
DR   P0C0C1, GCH1_STRPY ;  B5XLE8, GCH1_STRPZ ;  P59656, GCH1_STRR6 ;
DR   A4W1S9, GCH1_STRS2 ;  A3CKF4, GCH1_STRSV ;  A4VVH1, GCH1_STRSY ;
DR   Q5LYM8, GCH1_STRT1 ;  Q5M391, GCH1_STRT2 ;  C1CC81, GCH1_STRZJ ;
DR   C1CIH2, GCH1_STRZP ;  C1CPG4, GCH1_STRZT ;  Q4J8S2, GCH1_SULAC ;
DR   C3MZ97, GCH1_SULIA ;  C4KIH5, GCH1_SULIK ;  C3MR62, GCH1_SULIL ;
DR   C3MXF1, GCH1_SULIM ;  C3NGB7, GCH1_SULIN ;  C3N7B7, GCH1_SULIY ;
DR   Q980E8, GCH1_SULSO ;  B2V9P4, GCH1_SULSY ;  Q971G9, GCH1_SULTO ;
DR   Q54769, GCH1_SYNE7 ;  Q2JR69, GCH1_SYNJA ;  Q2JPT8, GCH1_SYNJB ;
DR   Q5N623, GCH1_SYNP6 ;  Q55759, GCH1_SYNY3 ;  C5BL73, GCH1_TERTT ;
DR   Q8DJB8, GCH1_THEEB ;  Q47KU5, GCH1_THEFY ;  B1YCT7, GCH1_THENV ;
DR   B0KCE5, GCH1_THEP3 ;  B0K5C1, GCH1_THEPX ;  Q8R7N2, GCH1_THETN ;
DR   B5YJV0, GCH1_THEYD ;  C4LDE6, GCH1_TOLAT ;  Q9KLX5, GCH1_VIBCH ;
DR   Q5E4E4, GCH1_VIBF1 ;  B5FF36, GCH1_VIBFM ;  A7N6L2, GCH1_VIBHB ;
DR   Q87GZ6, GCH1_VIBPA ;  Q8D6I7, GCH1_VIBVU ;  Q7MDE5, GCH1_VIBVY ;
DR   Q8D2N7, GCH1_WIGBR ;  Q7M933, GCH1_WOLSU ;  Q8PEP3, GCH1_XANAC ;
DR   Q3BM80, GCH1_XANC5 ;  Q8P3B0, GCH1_XANCP ;  B2I4L2, GCH1_XYLF2 ;
DR   Q9PC02, GCH1_XYLFA ;  B0U794, GCH1_XYLFM ;  Q87D63, GCH1_XYLFT ;
DR   P51601, GCH1_YEAST ;  A1JU09, GCH1_YERE8 ;  A7FJL1, GCH1_YERP3 ;
DR   B2JZ02, GCH1_YERPB ;  Q8ZG15, GCH1_YERPE ;  A9R1B1, GCH1_YERPG ;
DR   B1JQJ4, GCH1_YERPY ;  Q1BR24, GCH41_BURCA;  B1K3S8, GCH41_BURCC;
DR   A0AYZ1, GCH41_BURCH;  Q39AS8, GCH41_BURS3;  Q47IT5, GCH41_DECAR;
DR   Q1LPE1, GCH41_RALME;  Q1BLY8, GCH42_BURCA;  B1K5N3, GCH42_BURCC;
DR   A0B338, GCH42_BURCH;  Q393P5, GCH42_BURS3;  Q47BI9, GCH42_DECAR;
DR   Q1LK35, GCH42_RALME;  Q6FBI2, GCH4_ACIAD ;  B2ULP4, GCH4_AKKM8 ;
DR   Q0VMK6, GCH4_ALCBS ;  Q0AA39, GCH4_ALHEH ;  B9MNP4, GCH4_ANATD ;
DR   Q5P229, GCH4_AROAE ;  A1K4Q9, GCH4_AZOSB ;  C1DM03, GCH4_AZOVD ;
DR   Q9KE60, GCH4_BACHD ;  Q65ML7, GCH4_BACLD ;  P94398, GCH4_BACSU ;
DR   Q6MKE9, GCH4_BDEBA ;  Q2KZ16, GCH4_BORA1 ;  Q7WL36, GCH4_BORBR ;
DR   Q7W7P9, GCH4_BORPA ;  A9ITA7, GCH4_BORPD ;  Q7VV88, GCH4_BORPE ;
DR   B1Z1G3, GCH4_BURA4 ;  Q0BAL7, GCH4_BURCM ;  A9ANA1, GCH4_BURM1 ;
DR   A3MBD3, GCH4_BURM7 ;  A2S0N7, GCH4_BURM9 ;  Q62DU0, GCH4_BURMA ;
DR   A1UYQ5, GCH4_BURMS ;  A3P7W3, GCH4_BURP0 ;  Q3JKA4, GCH4_BURP1 ;
DR   A3NMF5, GCH4_BURP6 ;  B2JP67, GCH4_BURP8 ;  Q63JF5, GCH4_BURPS ;
DR   Q2T7N4, GCH4_BURTA ;  A4JLT5, GCH4_BURVG ;  Q13RX0, GCH4_BURXL ;
DR   A4XG24, GCH4_CALS8 ;  Q1R153, GCH4_CHRSD ;  A8AF20, GCH4_CITK8 ;
DR   Q47VM6, GCH4_COLP3 ;  B5Y6R9, GCH4_COPPD ;  Q0K861, GCH4_CUPNH ;
DR   Q474C1, GCH4_CUPPJ ;  A9C020, GCH4_DELAS ;  C6C0U6, GCH4_DESAD ;
DR   B8J1Q5, GCH4_DESDA ;  Q30X45, GCH4_DESDG ;  A8ZUJ6, GCH4_DESOH ;
DR   Q6AMT5, GCH4_DESPS ;  Q727G3, GCH4_DESVH ;  B8DLK8, GCH4_DESVM ;
DR   A1VAN0, GCH4_DESVV ;  A5EXB0, GCH4_DICNV ;  B5YCT4, GCH4_DICT6 ;
DR   B8DZH0, GCH4_DICTD ;  A8LS52, GCH4_DINSH ;  B1YHT1, GCH4_EXIS2 ;
DR   C4KZ55, GCH4_EXISA ;  A7HKP2, GCH4_FERNB ;  B5EDQ6, GCH4_GEOBB ;
DR   Q39R36, GCH4_GEOMG ;  Q74FW8, GCH4_GEOSL ;  C6E7E6, GCH4_GEOSM ;
DR   A5G8S1, GCH4_GEOUR ;  Q2SLC0, GCH4_HAHCH ;  A1WYI8, GCH4_HALHL ;
DR   A4G1X0, GCH4_HERAR ;  Q5R041, GCH4_IDILO ;  A6SUS5, GCH4_JANMA ;
DR   Q28R88, GCH4_JANSC ;  Q6U5S4, GCH4_KLEPN ;  C5CEC0, GCH4_KOSOT ;
DR   Q1MPD2, GCH4_LAWIP ;  B9E8N6, GCH4_MACCJ ;  A0L8I1, GCH4_MAGSM ;
DR   Q605G6, GCH4_METCA ;  Q1GZD6, GCH4_METFK ;  A2SJ45, GCH4_METPP ;
DR   Q5F9K6, GCH4_NEIG1 ;  A9M3N5, GCH4_NEIM0 ;  Q9JV35, GCH4_NEIMA ;
DR   Q9K023, GCH4_NEIMB ;  A1KT61, GCH4_NEIMF ;  Q0AFY5, GCH4_NITEC ;
DR   Q82VD1, GCH4_NITEU ;  Q2YCH6, GCH4_NITMU ;  Q3J9J7, GCH4_NITOC ;
DR   Q8EQK9, GCH4_OCEIH ;  B1ZTR5, GCH4_OPITP ;  A1BA17, GCH4_PARDP ;
DR   Q3A091, GCH4_PELCD ;  A1AU47, GCH4_PELPD ;  A4SZK2, GCH4_POLSQ ;
DR   Q48HN1, GCH4_PSE14 ;  Q15Z55, GCH4_PSEA6 ;  A6VF17, GCH4_PSEA7 ;
DR   B7V776, GCH4_PSEA8 ;  Q02DG9, GCH4_PSEAB ;  Q9HT35, GCH4_PSEAE ;
DR   Q1I2L2, GCH4_PSEE4 ;  Q4K3E8, GCH4_PSEF5 ;  C3K4H5, GCH4_PSEFS ;
DR   Q3ILJ5, GCH4_PSEHT ;  A4Y119, GCH4_PSEMY ;  A5W348, GCH4_PSEP1 ;
DR   Q3K4B0, GCH4_PSEPF ;  B0KR89, GCH4_PSEPG ;  Q88HM9, GCH4_PSEPK ;
DR   B1JFN3, GCH4_PSEPW ;  Q882P7, GCH4_PSESM ;  Q4ZU60, GCH4_PSEU2 ;
DR   A1STF0, GCH4_PSYIN ;  Q8XX96, GCH4_RALSO ;  A3PH01, GCH4_RHOS1 ;
DR   Q3J5D3, GCH4_RHOS4 ;  A4WQ81, GCH4_RHOS5 ;  B9KM22, GCH4_RHOSK ;
DR   Q168P4, GCH4_ROSDO ;  A1AVX5, GCH4_RUTMC ;  A8GF39, GCH4_SERP5 ;
DR   Q5LTR1, GCH4_SILPO ;  Q1GF96, GCH4_SILST ;  A7WZ02, GCH4_STAA1 ;
DR   A6TZ43, GCH4_STAA2 ;  Q2FJ74, GCH4_STAA3 ;  Q2G0L1, GCH4_STAA8 ;
DR   A5IQC0, GCH4_STAA9 ;  Q2YS98, GCH4_STAAB ;  Q5HIA9, GCH4_STAAC ;
DR   A6QEL9, GCH4_STAAE ;  Q99W43, GCH4_STAAM ;  Q7A777, GCH4_STAAN ;
DR   Q6GJA3, GCH4_STAAR ;  Q6GBS1, GCH4_STAAS ;  A8YZR4, GCH4_STAAT ;
DR   Q8NXX2, GCH4_STAAW ;  B9DKT0, GCH4_STACT ;  Q5HRI1, GCH4_STAEQ ;
DR   Q8CTR6, GCH4_STAES ;  Q4L3P5, GCH4_STAHJ ;  Q49VB3, GCH4_STAS1 ;
DR   Q2LUP0, GCH4_SYNAS ;  A0LQR3, GCH4_SYNFM ;  B7ICT4, GCH4_THEAB ;
DR   A8F7Q8, GCH4_THELT ;  A6LKE7, GCH4_THEM4 ;  Q9WXP6, GCH4_THEMA ;
DR   B9K795, GCH4_THENN ;  A5IL29, GCH4_THEP1 ;  B1LAA9, GCH4_THESQ ;
DR   Q31EF8, GCH4_THICR ;  Q3SKF2, GCH4_THIDA ;  A5CXA1, GCH4_VESOH ;
DR   Q8PLL4, GCH4_XANAC ;  Q3BUL9, GCH4_XANC5 ;  Q4UTV2, GCH4_XANC8 ;
DR   B0RTU4, GCH4_XANCB ;  Q8P9T3, GCH4_XANCP ;  Q2P374, GCH4_XANOM ;
DR   B2SJL4, GCH4_XANOP ;  Q5H0A0, GCH4_XANOR ;  B2IAI3, GCH4_XYLF2 ;
DR   Q9PBP4, GCH4_XYLFA ;  B0U741, GCH4_XYLFM ;  Q87DA5, GCH4_XYLFT ;
//
ID   3.5.4.17
DE   Adenosine-phosphate deaminase.
CA   5'-AMP + H(2)O = 5'-IMP + NH(3).
CC   -!- Acts on 5'-AMP, ADP, ATP, NAD(+) and adenosine, in decreasing order
CC       of activity.
CC   -!- The bacterial enzyme also acts on the deoxy derivatives (cf.
CC       EC 3.5.4.6).
//
ID   3.5.4.18
DE   ATP deaminase.
CA   ATP + H(2)O = ITP + NH(3).
//
ID   3.5.4.19
DE   Phosphoribosyl-AMP cyclohydrolase.
CA   1-(5-phosphoribosyl)-AMP + H(2)O = 1-(5-phosphoribosyl)-5-
CA   ((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide.
CC   -!- The Neurospora crassa enzyme also catalyzes the reactions of
CC       EC 1.1.1.23 and EC 3.6.1.31.
DR   O67780, HIS2_AQUAE ;  O82768, HIS2_ARATH ;  Q9K6Z7, HIS2_BACHD ;
DR   O34912, HIS2_BACSU ;  Q8A7Z7, HIS2_BACTN ;  Q7VQW4, HIS2_BLOFL ;
DR   P57207, HIS2_BUCAI ;  Q9ZHE0, HIS2_BUCAP ;  Q89AX6, HIS2_BUCBP ;
DR   Q9PM71, HIS2_CAMJE ;  O74712, HIS2_CANAL ;  Q9RWD6, HIS2_DEIRA ;
DR   Q9S5G3, HIS2_ECO57 ;  Q8FG47, HIS2_ECOL6 ;  P06989, HIS2_ECOLI ;
DR   Q7NLB5, HIS2_GLOVI ;  P44434, HIS2_HAEIN ;  Q7VJ02, HIS2_HELHP ;
DR   O24714, HIS2_KLEPN ;  O13471, HIS2_KLULA ;  Q02130, HIS2_LACLA ;
DR   P07685, HIS2_NEUCR ;  Q8YS28, HIS2_NOSS1 ;  Q8CXM8, HIS2_OCEIH ;
DR   Q9CLL8, HIS2_PASMU ;  Q7N6I6, HIS2_PHOLL ;  P62349, HIS2_PHOPR ;
DR   P45353, HIS2_PICPA ;  Q7VD07, HIS2_PROMA ;  Q7TV28, HIS2_PROMM ;
DR   Q7TUC7, HIS2_PROMP ;  P58853, HIS2_PYRFU ;  Q12670, HIS2_SACBA ;
DR   Q8Z5J6, HIS2_SALTI ;  P10367, HIS2_SALTY ;  O59667, HIS2_SCHPO ;
DR   Q8EFB6, HIS2_SHEON ;  P37793, HIS2_SHIFL ;  Q3Z0F9, HIS2_SHISS ;
DR   Q5HCM5, HIS2_STAAC ;  P64355, HIS2_STAAM ;  P64356, HIS2_STAAN ;
DR   Q6GDD2, HIS2_STAAR ;  Q6G603, HIS2_STAAS ;  Q8NUI4, HIS2_STAAW ;
DR   Q5HKP3, HIS2_STAEQ ;  Q8CQ91, HIS2_STAES ;  Q7U635, HIS2_SYNPX ;
DR   P74755, HIS2_SYNY3 ;  Q8DM88, HIS2_THEEB ;  Q9X0C5, HIS2_THEMA ;
DR   Q9RPQ3, HIS2_THEP3 ;  P62350, HIS2_THET2 ;  Q8R886, HIS2_THETN ;
DR   Q9KSW7, HIS2_VIBCH ;  Q87QK5, HIS2_VIBPA ;  Q8D8Q6, HIS2_VIBVU ;
DR   Q7MLS0, HIS2_VIBVY ;  Q7MAQ8, HIS2_WOLSU ;  Q8PLG5, HIS2_XANAC ;
DR   Q8P9N8, HIS2_XANCP ;  Q9PBD1, HIS2_XYLFA ;  Q87C35, HIS2_XYLFT ;
DR   P00815, HIS2_YEAST ;  Q8ZFY1, HIS2_YERPE ;  Q4KJL5, HIS31_PSEF5;
DR   Q4K3E4, HIS32_PSEF5;  A1TL07, HIS3_ACIAC ;  A0LTT2, HIS3_ACIC1 ;
DR   A5G0S8, HIS3_ACICJ ;  B9MDW4, HIS3_ACIET ;  A1W445, HIS3_ACISJ ;
DR   B9JFG9, HIS3_AGRRK ;  Q8UEK7, HIS3_AGRT5 ;  Q0VML6, HIS3_ALCBS ;
DR   Q0A9D7, HIS3_ALHEH ;  Q3M244, HIS3_ANAVT ;  O28329, HIS3_ARCFU ;
DR   Q5P796, HIS3_AROAE ;  A1R5S3, HIS3_ARTAT ;  A0JVK7, HIS3_ARTS2 ;
DR   Q43925, HIS3_AZOCH ;  A1KAV3, HIS3_AZOSB ;  C1DHS5, HIS3_AZOVD ;
DR   C3L9P6, HIS3_BACAC ;  A0RBM3, HIS3_BACAH ;  P60540, HIS3_BACAN ;
DR   B7JFZ6, HIS3_BACC0 ;  P62393, HIS3_BACC1 ;  B7INA4, HIS3_BACC2 ;
DR   C1EMQ8, HIS3_BACC3 ;  B7HHG6, HIS3_BACC4 ;  B7HKD5, HIS3_BACC7 ;
DR   A7GMV1, HIS3_BACCN ;  B9IV01, HIS3_BACCQ ;  Q81G01, HIS3_BACCR ;
DR   Q63DW7, HIS3_BACCZ ;  Q6HLE2, HIS3_BACHK ;  A1A1I6, HIS3_BIFAA ;
DR   B3DRT9, HIS3_BIFLD ;  Q8G6F6, HIS3_BIFLO ;  B7GQS6, HIS3_BIFLS ;
DR   Q2KTT0, HIS3_BORA1 ;  Q7WDX8, HIS3_BORBR ;  Q7W2X8, HIS3_BORPA ;
DR   A9HWB8, HIS3_BORPD ;  Q7VSY5, HIS3_BORPE ;  Q89IW3, HIS3_BRAJA ;
DR   A5ELY1, HIS3_BRASB ;  A4YSB5, HIS3_BRASO ;  B2S5T1, HIS3_BRUA1 ;
DR   Q2YQ02, HIS3_BRUA2 ;  Q57D60, HIS3_BRUAB ;  A9M587, HIS3_BRUC2 ;
DR   C0RJ48, HIS3_BRUMB ;  Q8YH95, HIS3_BRUME ;  B0CGM5, HIS3_BRUSI ;
DR   Q8G0L3, HIS3_BRUSU ;  B1YRW2, HIS3_BURA4 ;  Q1BS32, HIS3_BURCA ;
DR   B1JUA6, HIS3_BURCC ;  A0K3V9, HIS3_BURCH ;  B4E642, HIS3_BURCJ ;
DR   Q0BIW3, HIS3_BURCM ;  Q845U6, HIS3_BURM1 ;  A3MPU3, HIS3_BURM7 ;
DR   A2S755, HIS3_BURM9 ;  Q62GE6, HIS3_BURMA ;  A1V8H6, HIS3_BURMS ;
DR   A3P026, HIS3_BURP0 ;  Q3JN03, HIS3_BURP1 ;  A3NE92, HIS3_BURP6 ;
DR   Q63Q93, HIS3_BURPS ;  Q39K84, HIS3_BURS3 ;  A4JAX0, HIS3_BURVG ;
DR   B8GZS0, HIS3_CAUCN ;  Q9AAY5, HIS3_CAUCR ;  B0T5D0, HIS3_CAUSK ;
DR   B3PK83, HIS3_CELJU ;  A0RZ79, HIS3_CENSY ;  Q3AT43, HIS3_CHLCH ;
DR   B3EFT2, HIS3_CHLL2 ;  B3QLJ0, HIS3_CHLP8 ;  B3EM52, HIS3_CHLPB ;
DR   A1BDQ9, HIS3_CHLPD ;  B3QU88, HIS3_CHLT3 ;  Q8KF68, HIS3_CHLTE ;
DR   Q1QWC3, HIS3_CHRSD ;  Q7P0E7, HIS3_CHRVO ;  A5CRW1, HIS3_CLAM3 ;
DR   B0REU6, HIS3_CLAMS ;  Q97KH7, HIS3_CLOAB ;  A7FU83, HIS3_CLOB1 ;
DR   C3KVX7, HIS3_CLOB6 ;  A6LT23, HIS3_CLOB8 ;  B2UX19, HIS3_CLOBA ;
DR   A5I247, HIS3_CLOBH ;  C1FN43, HIS3_CLOBJ ;  B1ILB1, HIS3_CLOBK ;
DR   P60541, HIS3_CORDI ;  Q8FP00, HIS3_COREF ;  A4QFF8, HIS3_CORGB ;
DR   Q8NNT9, HIS3_CORGL ;  Q4JW51, HIS3_CORJK ;  Q0K694, HIS3_CUPNH ;
DR   Q46WL9, HIS3_CUPPJ ;  B3R793, HIS3_CUPTR ;  Q47AM4, HIS3_DECAR ;
DR   A9BXA2, HIS3_DELAS ;  B8FLE7, HIS3_DESAA ;  C0QLA8, HIS3_DESAH ;
DR   Q30VD6, HIS3_DESDG ;  A8ZXG8, HIS3_DESOH ;  Q6AJV8, HIS3_DESPS ;
DR   P62386, HIS3_DESVH ;  A1VHE5, HIS3_DESVV ;  A8LK58, HIS3_DINSH ;
DR   Q2NAM2, HIS3_ERYLH ;  Q0RFX5, HIS3_FRAAA ;  B5EE14, HIS3_GEOBB ;
DR   B3E6L7, HIS3_GEOLS ;  Q39UE8, HIS3_GEOMG ;  B9M8U6, HIS3_GEOSF ;
DR   P60542, HIS3_GEOSL ;  C6E0X3, HIS3_GEOSM ;  A5G6I6, HIS3_GEOUR ;
DR   Q5FPD9, HIS3_GLUOX ;  Q0BTI5, HIS3_GRABC ;  A1WXS8, HIS3_HALHL ;
DR   Q5UZH6, HIS3_HALMA ;  B0R7I1, HIS3_HALS3 ;  Q9HN23, HIS3_HALSA ;
DR   Q18DH0, HIS3_HALWD ;  A4G9I5, HIS3_HERAR ;  Q0BWU4, HIS3_HYPNA ;
DR   A8A9Z2, HIS3_IGNH4 ;  A6T375, HIS3_JANMA ;  Q28PE4, HIS3_JANSC ;
DR   Q039B6, HIS3_LACC3 ;  B3WED0, HIS3_LACCB ;  Q88UE4, HIS3_LACPL ;
DR   Q6AF72, HIS3_LEIXX ;  B1XX97, HIS3_LEPCP ;  P62392, HIS3_LEPIC ;
DR   Q8F8K4, HIS3_LEPIN ;  Q92E89, HIS3_LISIN ;  C1L0J1, HIS3_LISMC ;
DR   Q722Y8, HIS3_LISMF ;  B8DA63, HIS3_LISMH ;  Q8Y9G6, HIS3_LISMO ;
DR   A0AG14, HIS3_LISW6 ;  Q2W4W4, HIS3_MAGSA ;  A0LCF4, HIS3_MAGSM ;
DR   A1U670, HIS3_MARAV ;  Q11JM5, HIS3_MESSB ;  A6UT21, HIS3_META3 ;
DR   Q8TS96, HIS3_METAC ;  A7I9M0, HIS3_METB6 ;  Q465C4, HIS3_METBF ;
DR   Q12V48, HIS3_METBU ;  Q603K4, HIS3_METCA ;  Q1H4R1, HIS3_METFK ;
DR   Q2FPA4, HIS3_METHJ ;  Q58825, HIS3_METJA ;  P58836, HIS3_METKA ;
DR   A2STB6, HIS3_METLZ ;  A4FZQ7, HIS3_METM5 ;  A9A817, HIS3_METM6 ;
DR   A6VIS0, HIS3_METM7 ;  Q8PVE6, HIS3_METMA ;  A3CX32, HIS3_METMJ ;
DR   P62391, HIS3_METMP ;  A2SE10, HIS3_METPP ;  A5UMF9, HIS3_METS3 ;
DR   Q2NGK6, HIS3_METST ;  O26347, HIS3_METTH ;  A0B8B3, HIS3_METTP ;
DR   Q50837, HIS3_METVA ;  A6URR6, HIS3_METVS ;  C5CBK2, HIS3_MICLC ;
DR   A0QHH5, HIS3_MYCA1 ;  P0A5B4, HIS3_MYCBO ;  A1KJ22, HIS3_MYCBP ;
DR   C1ANM8, HIS3_MYCBT ;  A4T9N1, HIS3_MYCGI ;  B8ZRB5, HIS3_MYCLB ;
DR   Q9X7C3, HIS3_MYCLE ;  B2HQA9, HIS3_MYCMM ;  P60543, HIS3_MYCPA ;
DR   A0QX88, HIS3_MYCS2 ;  A3Q124, HIS3_MYCSJ ;  A1UHK1, HIS3_MYCSK ;
DR   Q1B7H1, HIS3_MYCSS ;  A5U2W2, HIS3_MYCTA ;  P0A5B3, HIS3_MYCTU ;
DR   A0PP21, HIS3_MYCUA ;  A1T8W8, HIS3_MYCVP ;  Q3IMJ0, HIS3_NATPD ;
DR   Q5FA24, HIS3_NEIG1 ;  B4RJN2, HIS3_NEIG2 ;  Q9JVH6, HIS3_NEIMA ;
DR   Q9K0H5, HIS3_NEIMB ;  A1KSN5, HIS3_NEIMF ;  Q0AEU0, HIS3_NITEC ;
DR   Q82WM6, HIS3_NITEU ;  Q1QMS2, HIS3_NITHX ;  A9A5W9, HIS3_NITMS ;
DR   Q2YAV1, HIS3_NITMU ;  Q3J6Q0, HIS3_NITOC ;  Q3ST00, HIS3_NITWN ;
DR   Q5YYP1, HIS3_NOCFA ;  A1SL49, HIS3_NOCSJ ;  A6X0X1, HIS3_OCHA4 ;
DR   A1B9F2, HIS3_PARDP ;  Q3A2Z2, HIS3_PELCD ;  Q3B281, HIS3_PELLD ;
DR   B4SCX8, HIS3_PELPB ;  A1AT71, HIS3_PELPD ;  A5CZ72, HIS3_PELTS ;
DR   A1VK43, HIS3_POLNA ;  Q12FC6, HIS3_POLSJ ;  B4S4Y9, HIS3_PROA2 ;
DR   Q6A8P2, HIS3_PROAC ;  A4SG83, HIS3_PROVI ;  Q48PJ7, HIS3_PSE14 ;
DR   A6VDI9, HIS3_PSEA7 ;  B7V3F9, HIS3_PSEA8 ;  Q02EV1, HIS3_PSEAB ;
DR   Q9HUB7, HIS3_PSEAE ;  Q1I3S7, HIS3_PSEE4 ;  A5WA48, HIS3_PSEP1 ;
DR   Q3KJC8, HIS3_PSEPF ;  B0KM39, HIS3_PSEPG ;  Q88D15, HIS3_PSEPK ;
DR   B1J2S5, HIS3_PSEPW ;  Q87UY9, HIS3_PSESM ;  Q4ZZG6, HIS3_PSEU2 ;
DR   A4VGE2, HIS3_PSEU5 ;  Q8ZY39, HIS3_PYRAE ;  A3MSF2, HIS3_PYRCJ ;
DR   Q1LIB3, HIS3_RALME ;  B2UEE4, HIS3_RALPJ ;  Q8XV86, HIS3_RALSO ;
DR   A9WR59, HIS3_RENSM ;  B3PNV9, HIS3_RHIE6 ;  Q2K853, HIS3_RHIEC ;
DR   Q1MGA3, HIS3_RHIL3 ;  Q98LQ5, HIS3_RHILO ;  B5ZQK7, HIS3_RHILW ;
DR   Q92QB5, HIS3_RHIME ;  C3MB44, HIS3_RHISN ;  Q7UJC4, HIS3_RHOBA ;
DR   B6IMI3, HIS3_RHOCS ;  C1A0L2, HIS3_RHOE4 ;  Q21U90, HIS3_RHOFD ;
DR   C1ATY6, HIS3_RHOOB ;  Q2IY19, HIS3_RHOP2 ;  Q07P45, HIS3_RHOP5 ;
DR   P60544, HIS3_RHOPA ;  Q212N1, HIS3_RHOPB ;  Q134L8, HIS3_RHOPS ;
DR   B3QE24, HIS3_RHOPT ;  Q2RTY3, HIS3_RHORT ;  A3PJ78, HIS3_RHOS1 ;
DR   Q53158, HIS3_RHOS4 ;  A4WRQ0, HIS3_RHOS5 ;  B9KRK6, HIS3_RHOSK ;
DR   Q0SHY8, HIS3_RHOSR ;  Q166D6, HIS3_ROSDO ;  A1AVW3, HIS3_RUTMC ;
DR   Q21FQ0, HIS3_SACD2 ;  A4FLL5, HIS3_SACEN ;  Q2S3T1, HIS3_SALRD ;
DR   Q5LST2, HIS3_SILPO ;  Q1GGT9, HIS3_SILST ;  A6U8C1, HIS3_SINMW ;
DR   Q01ZT9, HIS3_SOLUE ;  Q1GSW9, HIS3_SPHAL ;  A5V3S9, HIS3_SPHWW ;
DR   Q82A89, HIS3_STRAW ;  Q9S2U1, HIS3_STRCO ;  A8AY23, HIS3_STRGC ;
DR   B1W0N3, HIS3_STRGG ;  Q8DTR4, HIS3_STRMU ;  A3CNS9, HIS3_STRSV ;
DR   Q03K83, HIS3_STRTD ;  O33778, HIS3_SULSO ;  Q970Y6, HIS3_SULTO ;
DR   Q2LVG1, HIS3_SYNAS ;  A0LQM0, HIS3_SYNFM ;  Q47QS0, HIS3_THEFY ;
DR   Q31J60, HIS3_THICR ;  Q3SEU9, HIS3_THIDA ;  B8GU33, HIS3_THISH ;
DR   Q0W7V3, HIS3_UNCMA ;  A1WFT0, HIS3_VEREI ;  A5CXC7, HIS3_VESOH ;
DR   Q9X3W1, HIS3_ZYMMO ;
//
ID   3.5.4.20
DE   Pyrithiamine deaminase.
CA   1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-
CA   methylpyridinium bromide + H(2)O = 1-(4-hydroxy-2-methylpyrimid-5-
CA   ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + NH(3).
//
ID   3.5.4.21
DE   Creatinine deaminase.
CA   Creatinine + H(2)O = N-methylhydantoin + NH(3).
//
ID   3.5.4.22
DE   1-pyrroline-4-hydroxy-2-carboxylate deaminase.
CA   1-pyrroline-4-hydroxy-2-carboxylate + H(2)O = 2,5-dioxopentanoate +
CA   NH(3).
//
ID   3.5.4.23
DE   Blasticidin-S deaminase.
CA   Blasticidin S + H(2)O = deaminohydroxyblasticidin S + NH(3).
CC   -!- Catalyzes the deamination of the cytosine group of the antibiotics
CC       blasticidin S, cytomycin and acetylblasticidin S.
PR   PROSITE; PDOC00702;
DR   P0C2P0, BSD_ASPTE  ;  P0C2P1, BSD_ASPTN  ;  P0CI02, BSD_COCIM  ;
DR   P33967, BSR_BACCE  ;
//
ID   3.5.4.24
DE   Sepiapterin deaminase.
CA   Sepiapterin + H(2)O = xanthopterin-B(2) + NH(3).
CC   -!- Also acts on isosepiapterin, more slowly.
//
ID   3.5.4.25
DE   GTP cyclohydrolase II.
CA   GTP + 3 H(2)O = formate + 2,5-diamino-6-hydroxy-4-(5-phospho-D-
CA   ribosylamino)pyrimidine + diphosphate.
CC   -!- Two C-N bonds are hydrolyzed, releasing formate, with simultaneous
CC       removal of the terminal diphosphate.
DR   P50139, RIB1_PICGU ;  Q9P7M9, RIB1_SCHPO ;  P38066, RIB1_YEAST ;
DR   Q6F7N4, RIBA_ACIAD ;  B7GVX4, RIBA_ACIB3 ;  B7IA66, RIBA_ACIB5 ;
DR   B2HZQ0, RIBA_ACIBC ;  B0VQB7, RIBA_ACIBS ;  A3M9B0, RIBA_ACIBT ;
DR   B0V709, RIBA_ACIBY ;  A6VPG3, RIBA_ACTSZ ;  A0KJ91, RIBA_AERHH ;
DR   B6ENI2, RIBA_ALISL ;  O29766, RIBA_ARCFU ;  P43525, RIBA_AZOBR ;
DR   C1DLI3, RIBA_AZOVD ;  Q1LTG5, RIBA_BAUCH ;  Q7VR05, RIBA_BLOFL ;
DR   Q492N9, RIBA_BLOPB ;  P57359, RIBA_BUCAI ;  Q8K9Q0, RIBA_BUCAP ;
DR   P59555, RIBA_BUCBP ;  Q62BG3, RIBA_BURMA ;  A0RR75, RIBA_CAMFF ;
DR   A7I3X0, RIBA_CAMHC ;  A8AG83, RIBA_CITK8 ;  Q47WV5, RIBA_COLP3 ;
DR   O68248, RIBA_DEHMU ;  A7ZL97, RIBA_ECO24 ;  B7UR85, RIBA_ECO27 ;
DR   B7MLV3, RIBA_ECO45 ;  B7L4B3, RIBA_ECO55 ;  P0A7I8, RIBA_ECO57 ;
DR   B5YZQ8, RIBA_ECO5E ;  B7NVQ1, RIBA_ECO7I ;  B7MUB9, RIBA_ECO81 ;
DR   B7LY36, RIBA_ECO8A ;  C4ZTX2, RIBA_ECOBW ;  B1XBM8, RIBA_ECODH ;
DR   A7ZZL5, RIBA_ECOHS ;  Q0TI88, RIBA_ECOL5 ;  Q8FHU5, RIBA_ECOL6 ;
DR   B1ITH7, RIBA_ECOLC ;  P0A7I7, RIBA_ECOLI ;  B7N493, RIBA_ECOLU ;
DR   B6I9Z2, RIBA_ECOSE ;  B1LH12, RIBA_ECOSM ;  A4WAY6, RIBA_ENT38 ;
DR   A7MMF7, RIBA_ENTS8 ;  Q6D5U5, RIBA_ERWCT ;  B7LS01, RIBA_ESCF3 ;
DR   Q4QNX8, RIBA_HAEI8 ;  A5UAU5, RIBA_HAEIE ;  A5UG14, RIBA_HAEIG ;
DR   P44571, RIBA_HAEIN ;  Q0I4A3, RIBA_HAES1 ;  B0UUP7, RIBA_HAES2 ;
DR   Q2SA07, RIBA_HAHCH ;  C4K8Q4, RIBA_HAMD5 ;  Q17XC9, RIBA_HELAH ;
DR   Q7VK48, RIBA_HELHP ;  B6JM32, RIBA_HELP2 ;  Q1CT68, RIBA_HELPH ;
DR   Q9ZL42, RIBA_HELPJ ;  B2UT29, RIBA_HELPS ;  O08315, RIBA_HELPY ;
DR   B5XS13, RIBA_KLEP3 ;  A6T7Y5, RIBA_KLEP7 ;  Q65SC0, RIBA_MANSM ;
DR   A6VWW9, RIBA_MARMS ;  Q5F7N6, RIBA_NEIG1 ;  A9LZD5, RIBA_NEIM0 ;
DR   Q9JU99, RIBA_NEIMA ;  Q9JZ78, RIBA_NEIMB ;  A1KU62, RIBA_NEIMF ;
DR   P57863, RIBA_PASMU ;  P51618, RIBA_PHOPO ;  Q6L1J7, RIBA_PICTO ;
DR   B4EW08, RIBA_PROMH ;  A6V055, RIBA_PSEA7 ;  B7V7R1, RIBA_PSEA8 ;
DR   Q02SL4, RIBA_PSEAB ;  Q9HWY1, RIBA_PSEAE ;  Q1IFL5, RIBA_PSEE4 ;
DR   C3K2R5, RIBA_PSEFS ;  A5VXW5, RIBA_PSEP1 ;  B0KL75, RIBA_PSEPG ;
DR   Q88QH1, RIBA_PSEPK ;  B1J3G0, RIBA_PSEPW ;  Q889Q3, RIBA_PSESM ;
DR   A1SSA8, RIBA_PSYIN ;  Q21F24, RIBA_SACD2 ;  Q57NU9, RIBA_SALCH ;
DR   Q5PCY8, RIBA_SALPA ;  P66031, RIBA_SALTI ;  P66030, RIBA_SALTY ;
DR   A1S528, RIBA_SHEAM ;  B8EF62, RIBA_SHEB2 ;  A3D367, RIBA_SHEB5 ;
DR   A6WLV9, RIBA_SHEB8 ;  A9KXC4, RIBA_SHEB9 ;  Q12P94, RIBA_SHEDO ;
DR   Q080N2, RIBA_SHEFN ;  B0TL40, RIBA_SHEHH ;  A3QFR4, RIBA_SHELP ;
DR   Q8EDD1, RIBA_SHEON ;  A8H5U9, RIBA_SHEPA ;  A4Y5N5, RIBA_SHEPC ;
DR   B8CQ07, RIBA_SHEPW ;  A0KYF8, RIBA_SHESA ;  A8FTP1, RIBA_SHESH ;
DR   Q0HHF8, RIBA_SHESM ;  Q0HTR2, RIBA_SHESR ;  A1RL35, RIBA_SHESW ;
DR   B1KLM0, RIBA_SHEWM ;  B2U0G9, RIBA_SHIB3 ;  Q31ZX1, RIBA_SHIBS ;
DR   Q32GQ6, RIBA_SHIDS ;  Q0T5C0, RIBA_SHIF8 ;  P0A7I9, RIBA_SHIFL ;
DR   Q3Z127, RIBA_SHISS ;  O88011, RIBA_STRCO ;  C5BS80, RIBA_TERTT ;
DR   Q97B83, RIBA_THEVO ;  C4LE64, RIBA_TOLAT ;  Q9KSJ3, RIBA_VIBCH ;
DR   Q5E5L2, RIBA_VIBF1 ;  B5FDS3, RIBA_VIBFM ;  Q87NE7, RIBA_VIBPA ;
DR   Q8DAG7, RIBA_VIBVU ;  Q8D2J0, RIBA_WIGBR ;  Q9PBZ3, RIBA_XYLFA ;
DR   Q87D69, RIBA_XYLFT ;  Q8ZEF0, RIBA_YERPE ;  Q66AI6, RIBA_YERPS ;
DR   A3MZA2, RIBBA_ACTP2;  B3H0P8, RIBBA_ACTP7;  B0BTN8, RIBBA_ACTPJ;
DR   P50855, RIBBA_ACTPL;  O66679, RIBBA_AQUAE;  P47924, RIBBA_ARATH;
DR   A7Z675, RIBBA_BACA2;  C3P7P7, RIBBA_BACAA;  C3LIX7, RIBBA_BACAC;
DR   A0RIB3, RIBBA_BACAH;  P51695, RIBBA_BACAM;  Q81MB6, RIBBA_BACAN;
DR   B7JLW6, RIBBA_BACC0;  Q731I5, RIBBA_BACC1;  B7IWM5, RIBBA_BACC2;
DR   C1EQY5, RIBBA_BACC3;  B7HAY4, RIBBA_BACC4;  B7HNM8, RIBBA_BACC7;
DR   A7GSD5, RIBBA_BACCN;  B9IWX4, RIBBA_BACCQ;  Q818X6, RIBBA_BACCR;
DR   Q635H0, RIBBA_BACCZ;  Q5LHT1, RIBBA_BACFN;  Q64YT3, RIBBA_BACFR;
DR   Q6HE54, RIBBA_BACHK;  Q5WH08, RIBBA_BACSK;  P17620, RIBBA_BACSU;
DR   Q8A528, RIBBA_BACTN;  A6KWQ7, RIBBA_BACV8;  A9VG50, RIBBA_BACWK;
DR   C0ZKW2, RIBBA_BREBN;  Q9PLJ5, RIBBA_CHLMU;  Q9Z734, RIBBA_CHLPN;
DR   O84736, RIBBA_CHLTR;  A0Q3H7, RIBBA_CLONN;  O24752, RIBBA_CORAM;
DR   A4QEG9, RIBBA_CORGB;  Q8NQ52, RIBBA_CORGL;  Q11WK6, RIBBA_CYTH3;
DR   C5D3N0, RIBBA_GEOSW;  A0QI09, RIBBA_MYCA1;  B1MCA4, RIBBA_MYCA9;
DR   P0A5V1, RIBBA_MYCBO;  A1KIK4, RIBBA_MYCBP;  C1AN60, RIBBA_MYCBT;
DR   A4TC13, RIBBA_MYCGI;  B2HP67, RIBBA_MYCMM;  Q741F1, RIBBA_MYCPA;
DR   A5U2B7, RIBBA_MYCTA;  P0A5V0, RIBBA_MYCTU;  A0PPL6, RIBBA_MYCUA;
DR   A1T8K1, RIBBA_MYCVP;  Q5YTP3, RIBBA_NOCFA;  A6LHN0, RIBBA_PARD8;
DR   Q3B2I6, RIBBA_PELLD;  B4SE30, RIBBA_PELPB;  B2RIG7, RIBBA_PORG3;
DR   Q7MWK9, RIBBA_PORGI;  B4S5Y8, RIBBA_PROA2;  A4SFY4, RIBBA_PROVI;
DR   C0ZZE5, RIBBA_RHOE4;  Q0S0K2, RIBBA_RHOSR;  A8LY38, RIBBA_SALAI;
DR   A4X639, RIBBA_SALTO;  Q5HF07, RIBBA_STAAC;  Q99TA0, RIBBA_STAAM;
DR   Q7A511, RIBBA_STAAN;  Q6GFT5, RIBBA_STAAR;  Q6G8G1, RIBBA_STAAS;
DR   Q8NW14, RIBBA_STAAW;  Q5HNE3, RIBBA_STAEQ;  Q8CNU2, RIBBA_STAES;
DR   Q4L7B1, RIBBA_STAHJ;  Q49YJ7, RIBBA_STAS1;  Q0AXM5, RIBBA_SYNWW;
DR   P74104, RIBBA_SYNY3;  Q9X2E6, RIBBA_THEMA;  B0KAI2, RIBBA_THEP3;
DR   B0K0Y9, RIBBA_THEPX;  B1H0I0, RIBBA_UNCTG;
//
ID   3.5.4.26
DE   Diaminohydroxyphosphoribosylaminopyrimidine deaminase.
CA   2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine + H(2)O =
CA   5-amino-6-(5-phosphoribosylamino)uracil + NH(3).
CC   -!- The substrate is the product of EC 3.5.4.25.
DR   P87241, RIB2_SCHPO ;  Q12362, RIB2_YEAST ;  P57533, RIBD1_BUCAI;
DR   Q8K9A4, RIBD1_BUCAP;  P50853, RIBD_ACTPL ;  O66534, RIBD_AQUAE ;
DR   P70814, RIBD_BACAM ;  P17618, RIBD_BACSU ;  Q89AB0, RIBD_BUCBP ;
DR   Q9PLJ6, RIBD_CHLMU ;  Q9Z735, RIBD_CHLPN ;  O84735, RIBD_CHLTR ;
DR   O24750, RIBD_CORAM ;  P25539, RIBD_ECOLI ;  P44326, RIBD_HAEIN ;
DR   P71677, RIBD_MYCTU ;  Q55158, RIBD_SYNY3 ;
//
ID   3.5.4.27
DE   Methenyltetrahydromethanopterin cyclohydrolase.
AN   Methenyl-H(4)MPT cyclohydrolase.
CA   5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2)O = 5-formyl-5,6,7,8-
CA   tetrahydromethanopterin.
CC   -!- Methanopterin is a pterin analog.
CC   -!- Involved in the formation of methane from CO(2) in Methanobacterium
CC       thermoautotrophicum.
DR   O28344, MCH_ARCFU  ;  B0R653, MCH_HALS3  ;  Q9HPD7, MCH_HALSA  ;
DR   Q9RPW6, MCH_HYPME  ;  A6UU55, MCH_META3  ;  Q8TQ42, MCH_METAC  ;
DR   Q9RPW4, MCH_METAL  ;  A7I637, MCH_METB6  ;  P94919, MCH_METBF  ;
DR   Q12Y52, MCH_METBU  ;  Q9RPW8, MCH_METCA  ;  O85014, MCH_METEA  ;
DR   Q8KMJ5, MCH_METED  ;  Q9RQ04, MCH_METFK  ;  Q2FR24, MCH_METHJ  ;
DR   Q59030, MCH_METJA  ;  P94954, MCH_METKA  ;  A2SQG9, MCH_METLZ  ;
DR   A4FWY5, MCH_METM5  ;  A6VGD1, MCH_METM7  ;  Q8PTR0, MCH_METMA  ;
DR   Q9RPW5, MCH_METME  ;  A3CTA1, MCH_METMJ  ;  Q6LY02, MCH_METMP  ;
DR   B8ITX3, MCH_METNO  ;  Q9RPW7, MCH_METOR  ;  B8GDH2, MCH_METPE  ;
DR   Q9RPW2, MCH_METRU  ;  A5UP00, MCH_METS3  ;  B0UF36, MCH_METS4  ;
DR   O26867, MCH_METTH  ;  P51616, MCH_METTM  ;  Q9RPW3, MCH_METTO  ;
DR   Q9RPD4, MCH_METTR  ;  A6UPJ2, MCH_METVS  ;  Q7UPS1, MCH_RHOBA  ;
DR   Q0W8U9, MCH_UNCMA  ;  Q9RQ01, MCH_XANAU  ;
//
ID   3.5.4.28
DE   S-adenosylhomocysteine deaminase.
CA   S-adenosyl-L-homocysteine + H(2)O = S-inosyl-L-homocysteine + NH(3).
DR   O29701, MTAD1_ARCFU;  Q2LTB7, MTAD1_SYNAS;  O29265, MTAD2_ARCFU;
DR   Q2LUH4, MTAD2_SYNAS;  O66851, MTAD_AQUAE ;  C3P768, MTAD_BACAA ;
DR   C3L6N3, MTAD_BACAC ;  A0RCM7, MTAD_BACAH ;  Q81S14, MTAD_BACAN ;
DR   B7JJI0, MTAD_BACC0 ;  O31352, MTAD_BACC1 ;  B7IS56, MTAD_BACC2 ;
DR   C1EPN0, MTAD_BACC3 ;  B7HIQ2, MTAD_BACC4 ;  B7HMN9, MTAD_BACC7 ;
DR   A7GNR9, MTAD_BACCN ;  Q81F14, MTAD_BACCR ;  Q63CU1, MTAD_BACCZ ;
DR   Q9KC82, MTAD_BACHD ;  Q6HK87, MTAD_BACHK ;  Q5WGA8, MTAD_BACSK ;
DR   A4XJI3, MTAD_CALS8 ;  Q3AC64, MTAD_CARHZ ;  Q891Y7, MTAD_CLOTE ;
DR   A3DEQ2, MTAD_CLOTH ;  B1I2P4, MTAD_DESAP ;  B8J2Q8, MTAD_DESDA ;
DR   B8FRL9, MTAD_DESHD ;  Q24UA2, MTAD_DESHY ;  A4J675, MTAD_DESRM ;
DR   Q72B14, MTAD_DESVH ;  B8DKS6, MTAD_DESVM ;  A1VD37, MTAD_DESVV ;
DR   B5YDN9, MTAD_DICT6 ;  B8E183, MTAD_DICTD ;  Q5UYR3, MTAD_HALMA ;
DR   B8CX03, MTAD_HALOH ;  Q9HN51, MTAD_HALSA ;  Q18EV7, MTAD_HALWD ;
DR   Q1MR44, MTAD_LAWIP ;  A6UUG9, MTAD_META3 ;  Q8TRA4, MTAD_METAC ;
DR   A7I6C5, MTAD_METB6 ;  Q466Q9, MTAD_METBF ;  Q12WS1, MTAD_METBU ;
DR   Q2FRU6, MTAD_METHJ ;  Q58936, MTAD_METJA ;  Q8TYD4, MTAD_METKA ;
DR   A4FW32, MTAD_METM5 ;  A9A9H3, MTAD_METM6 ;  A6VH76, MTAD_METM7 ;
DR   Q8PUQ3, MTAD_METMA ;  Q6LX61, MTAD_METMP ;  A5UMN6, MTAD_METS3 ;
DR   Q2NHL6, MTAD_METST ;  O27549, MTAD_METTH ;  A0B7V2, MTAD_METTP ;
DR   A6UQD4, MTAD_METVS ;  Q2RJW1, MTAD_MOOTA ;  Q3ITF7, MTAD_NATPD ;
DR   A5D1G6, MTAD_PELTS ;  Q9V0Y5, MTAD_PYRAB ;  Q8U0P7, MTAD_PYRFU ;
DR   O59184, MTAD_PYRHO ;  Q5JER0, MTAD_PYRKO ;  Q21IS0, MTAD_SACD2 ;
DR   Q67NQ5, MTAD_SYMTH ;  A0LMI3, MTAD_SYNFM ;  Q0AYV2, MTAD_SYNWW ;
DR   C5BSJ0, MTAD_TERTT ;  Q9X034, MTAD_THEMA ;  B6YUF8, MTAD_THEON ;
DR   B0K8R8, MTAD_THEP3 ;  B0K2W0, MTAD_THEPX ;  C6A048, MTAD_THESM ;
DR   Q8R9L4, MTAD_THETN ;  B5YLB7, MTAD_THEYD ;
//
ID   3.5.4.29
DE   GTP cyclohydrolase IIa.
AN   GTP cyclohydrolase III.
CA   GTP + 3 H(2)O = 2-amino-5-formylamino-6-(5-phospho-D-
CA   ribosylamino)pyrimidin-4(3H)-one + 2 phosphate.
CF   Magnesium.
CC   -!- This enzyme catalyzes the hydrolysis of the imidazole ring of
CC       guanosine 5'-triphosphate, N(7)-methylguanosine 5'-triphosphate or
CC       inosine 5'-triphosphate.
CC   -!- Xanthosine 5'-triphosphate and ATP are not substrates.
CC   -!- It also catalyzes the hydrolysis of diphosphate to form two
CC       equivalents of phosphate.
CC   -!- Unlike EC 3.5.4.25, this enzyme does not release formate, but does
CC       hydrolyze the diphosphate from GTP to phosphate.
DR   Q9HQT7, GCH31_HALSA;  Q9HQS9, GCH32_HALSA;  Q9YC89, GCH3_AERPE ;
DR   B9LRB1, GCH3_HALLT ;  Q57609, GCH3_METJA ;  A4FZ97, GCH3_METM5 ;
DR   A9A6P4, GCH3_METM6 ;  A6VJ40, GCH3_METM7 ;  Q6M066, GCH3_METMP ;
DR   A5ULV0, GCH3_METS3 ;  Q2NEH8, GCH3_METST ;  O27096, GCH3_METTH ;
DR   A6US18, GCH3_METVS ;  Q3INZ0, GCH3_NATPD ;  Q8ZU20, GCH3_PYRAE ;
DR   A4WKJ7, GCH3_PYRAR ;  A3MV81, GCH3_PYRCJ ;  A1RRI0, GCH3_PYRIL ;
DR   C3MZ63, GCH3_SULIA ;  C4KIE1, GCH3_SULIK ;  C3MR15, GCH3_SULIL ;
DR   C3MX03, GCH3_SULIM ;  C3NGF2, GCH3_SULIN ;  C3N783, GCH3_SULIY ;
DR   Q980B6, GCH3_SULSO ;  Q975M4, GCH3_SULTO ;  B1YAW1, GCH3_THENV ;
//
ID   3.5.4.30
DE   dCTP deaminase (dUMP-forming).
CA   dCTP + 2 H(2)O = dUMP + diphosphate + NH(3).
CF   Magnesium.
CC   -!- Is highly specific for dCTP as substrate as dCMP, CTP, CDP, CMP,
CC       cytosine or deoxycytosine are not deaminated.
CC   -!- While most bacteria require two enzymes to form dUMP from dCTP
CC       (EC 3.5.4.13 and EC 3.6.1.23), the archaeon Methanocaldococcus
CC       jannaschii uses a single enzyme to carry out both functions.
CC   -!- This enzyme can also act as a dUTP diphosphatase, but more slowly.
DR   Q57872, DCD_METJA  ;
//
ID   3.5.4.n1
DE   5-methylthioadenosine deaminase.
AN   MTA deaminase.
CA   5-methylthioadenosine + H(2)O = 5-methylthioinosine + NH(3).
CC   -!- The enzyme from Thermotoga maritima also functions as
CC       S-adenosylhomocysteine deaminase (EC 3.5.4.28) and has some activity
CC       against adenosine.
CC   -!- Adenosine-5-monophosphate (AMP) and S-adenosyl-L-methionine (SAM) are
CC       not substrates.
DR   O29701, MTAD1_ARCFU;  Q2LTB7, MTAD1_SYNAS;  O29265, MTAD2_ARCFU;
DR   Q2LUH4, MTAD2_SYNAS;  O66851, MTAD_AQUAE ;  C3P768, MTAD_BACAA ;
DR   C3L6N3, MTAD_BACAC ;  A0RCM7, MTAD_BACAH ;  Q81S14, MTAD_BACAN ;
DR   B7JJI0, MTAD_BACC0 ;  O31352, MTAD_BACC1 ;  B7IS56, MTAD_BACC2 ;
DR   C1EPN0, MTAD_BACC3 ;  B7HIQ2, MTAD_BACC4 ;  B7HMN9, MTAD_BACC7 ;
DR   A7GNR9, MTAD_BACCN ;  Q81F14, MTAD_BACCR ;  Q63CU1, MTAD_BACCZ ;
DR   Q9KC82, MTAD_BACHD ;  Q6HK87, MTAD_BACHK ;  Q5WGA8, MTAD_BACSK ;
DR   A4XJI3, MTAD_CALS8 ;  Q3AC64, MTAD_CARHZ ;  Q891Y7, MTAD_CLOTE ;
DR   A3DEQ2, MTAD_CLOTH ;  B1I2P4, MTAD_DESAP ;  B8J2Q8, MTAD_DESDA ;
DR   B8FRL9, MTAD_DESHD ;  Q24UA2, MTAD_DESHY ;  A4J675, MTAD_DESRM ;
DR   Q72B14, MTAD_DESVH ;  B8DKS6, MTAD_DESVM ;  A1VD37, MTAD_DESVV ;
DR   B5YDN9, MTAD_DICT6 ;  B8E183, MTAD_DICTD ;  Q5UYR3, MTAD_HALMA ;
DR   B8CX03, MTAD_HALOH ;  Q9HN51, MTAD_HALSA ;  Q18EV7, MTAD_HALWD ;
DR   Q1MR44, MTAD_LAWIP ;  A6UUG9, MTAD_META3 ;  Q8TRA4, MTAD_METAC ;
DR   A7I6C5, MTAD_METB6 ;  Q466Q9, MTAD_METBF ;  Q12WS1, MTAD_METBU ;
DR   Q2FRU6, MTAD_METHJ ;  Q58936, MTAD_METJA ;  Q8TYD4, MTAD_METKA ;
DR   A4FW32, MTAD_METM5 ;  A9A9H3, MTAD_METM6 ;  A6VH76, MTAD_METM7 ;
DR   Q8PUQ3, MTAD_METMA ;  Q6LX61, MTAD_METMP ;  A5UMN6, MTAD_METS3 ;
DR   Q2NHL6, MTAD_METST ;  O27549, MTAD_METTH ;  A0B7V2, MTAD_METTP ;
DR   A6UQD4, MTAD_METVS ;  Q2RJW1, MTAD_MOOTA ;  Q3ITF7, MTAD_NATPD ;
DR   A5D1G6, MTAD_PELTS ;  Q9V0Y5, MTAD_PYRAB ;  Q8U0P7, MTAD_PYRFU ;
DR   O59184, MTAD_PYRHO ;  Q5JER0, MTAD_PYRKO ;  Q21IS0, MTAD_SACD2 ;
DR   Q67NQ5, MTAD_SYMTH ;  A0LMI3, MTAD_SYNFM ;  Q0AYV2, MTAD_SYNWW ;
DR   C5BSJ0, MTAD_TERTT ;  Q9X034, MTAD_THEMA ;  B6YUF8, MTAD_THEON ;
DR   B0K8R8, MTAD_THEP3 ;  B0K2W0, MTAD_THEPX ;  C6A048, MTAD_THESM ;
DR   Q8R9L4, MTAD_THETN ;  B5YLB7, MTAD_THEYD ;
//
ID   3.5.4.n2
DE   GTP cyclohydrolase (cyclic phosphate forming).
CA   GTP + H(2)O = formate + 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate +
CA   diphosphate.
CF   Iron.
CC   -!- Two C-N bonds are hydrolyzed, releasing formate, with simultaneous
CC       removal of the terminal diphosphate and formation of a cyclic
CC       phosphate group.
CC   -!- The enzyme is also able to utilize a variety of GTP analogs as
CC       substrates, including GDP, beta,gamma-methylene-GTP and GTP-(gamma-
CC       thio).
DR   Q0W6F5, MPTA1_UNCMA;  Q0W8U7, MPTA2_UNCMA;  Q9Y9I0, MPTA_AERPE ;
DR   O29088, MPTA_ARCFU ;  Q5UXK3, MPTA_HALMA ;  B0R6L9, MPTA_HALS3 ;
DR   Q9HNX6, MPTA_HALSA ;  Q18F47, MPTA_HALWD ;  B1L550, MPTA_KORCO ;
DR   A6UW53, MPTA_META3 ;  Q8THJ7, MPTA_METAC ;  A7I5I7, MPTA_METB6 ;
DR   Q46D91, MPTA_METBF ;  Q12ZQ0, MPTA_METBU ;  Q2FNB7, MPTA_METHJ ;
DR   Q58185, MPTA_METJA ;  Q8TY21, MPTA_METKA ;  A2SPE0, MPTA_METLZ ;
DR   A4G0F9, MPTA_METM5 ;  A9A8Q7, MPTA_METM6 ;  A6VI22, MPTA_METM7 ;
DR   Q8PXJ6, MPTA_METMA ;  A3CXJ6, MPTA_METMJ ;  Q6M183, MPTA_METMP ;
DR   A5UM10, MPTA_METS3 ;  Q2NI42, MPTA_METST ;  O27264, MPTA_METTH ;
DR   A0B624, MPTA_METTP ;  A6UR12, MPTA_METVS ;  Q3IR95, MPTA_NATPD ;
DR   Q6L0A8, MPTA_PICTO ;  Q9V1S9, MPTA_PYRAB ;  Q8TZZ2, MPTA_PYRFU ;
DR   O59447, MPTA_PYRHO ;  Q5JH75, MPTA_PYRKO ;  Q9HJ35, MPTA_THEAC ;
DR   Q979C3, MPTA_THEVO ;
//
ID   3.5.5.1
DE   Nitrilase.
CA   A nitrile + 2 H(2)O = a carboxylate + NH(3).
CC   -!- Acts on a wide range of aromatic nitriles including (indol-3-
CC       yl)acetonitrile, and also on some aliphatic nitriles, and on the
CC       corresponding acid amides (cf. EC 4.2.1.84).
PR   PROSITE; PDOC00712;
PR   PROSITE; PDOC50263;
DR   P32961, NRL1_ARATH ;  P32962, NRL2_ARATH ;  P46010, NRL3_ARATH ;
DR   Q42965, NRL4A_TOBAC;  Q42966, NRL4B_TOBAC;  P46011, NRL4_ARATH ;
DR   Q6H849, NRL4_ORYSJ ;  P33036, NRLA_ACISA ;  P20960, NRLA_ALCFA ;
DR   P10045, NRLB_KLEPO ;  P82605, NRL_BACSX  ;
//
ID   3.5.5.2
DE   Ricinine nitrilase.
CA   Ricinine + 2 H(2)O = 3-carboxy-4-methoxy-N-methyl-2-pyridone + NH(3).
//
ID   3.5.5.3
DE   Transferred entry: 4.2.1.104.
//
ID   3.5.5.4
DE   Cyanoalanine nitrilase.
CA   3-cyano-L-alanine + 2 H(2)O = L-aspartate + NH(3).
CC   -!- L-asparagine is formed as an intermediate.
DR   Q42965, NRL4A_TOBAC;  Q42966, NRL4B_TOBAC;  P46011, NRL4_ARATH ;
DR   Q6H849, NRL4_ORYSJ ;
//
ID   3.5.5.5
DE   Arylacetonitrilase.
CA   4-chlorophenylacetonitrile + 2 H(2)O = 4-chlorophenylacetate + NH(3).
CC   -!- Requires thiol compounds.
CC   -!- Also hydrolyzes other 4-substituted phenylacetonitriles, thien-2-
CC       ylacetonitrile, tolylacetonitriles, and, more slowly, benzyl cyanide.
//
ID   3.5.5.6
DE   Bromoxynil nitrilase.
CA   3,5-dibromo-4-hydroxybenzonitrile + 2 H(2)O = 3,5-dibromo-4-hydroxy-
CA   benzoate + NH(3).
CC   -!- Involved in the bacterial degradation of the herbicide bromoxynil.
CC   -!- Highly specific.
//
ID   3.5.5.7
DE   Aliphatic nitrilase.
CA   R-CN + 2 H(2)O = R-COOH + NH(3).
CC   -!- Preferentially hydrolyzes aliphatic nitriles, some of which are
CC       apparently not substrates for other known EC 3.5.5.1.
CC   -!- Substrates include crotononitrile, acrylonitrile and glutaronitrile.
PR   PROSITE; PDOC00712;
DR   Q02068, NRL1_RHORH ;  Q03217, NRL2_RHORH ;
//
ID   3.5.5.8
DE   Thiocyanate hydrolase.
CA   Thiocyanate + 2 H(2)O = carbonyl sulfide + NH(3) + HO(-).
CC   -!- The enzyme from Thiobacillus thioparus catalyzes the first step in
CC       the degradation of thiocyanate.
DR   O66187, SCNA_THITI ;  O66186, SCNB_THITI ;  O66188, SCNC_THITI ;
//
ID   3.5.99.1
DE   Riboflavinase.
CA   Riboflavin + H(2)O = ribitol + lumichrome.
//
ID   3.5.99.2
DE   Thiaminase.
AN   Thiaminase II.
CA   Thiamine + H(2)O = 4-amino-5-hydroxymethyl-2-methylpyrimidine +
CA   5-(2-hydroxyethyl)-4-methylthiazole.
DR   P25052, TENA_BACSU ;  Q2FF32, TENA_STAA3 ;  Q2FWG0, TENA_STAA8 ;
DR   Q2YUL0, TENA_STAAB ;  Q5HEA5, TENA_STAAC ;  Q99SG3, TENA_STAAM ;
DR   Q7A4F3, TENA_STAAN ;  Q6GEY1, TENA_STAAR ;  Q6G7L6, TENA_STAAS ;
DR   Q7A0C8, TENA_STAAW ;  O54496, TENA_STACT ;  Q5HMC7, TENA_STAEQ ;
DR   Q8CNK1, TENA_STAES ;  Q4L7X6, TENA_STAHJ ;  Q49Z42, TENA_STAS1 ;
//
ID   3.5.99.3
DE   Hydroxydechloroatrazine ethylaminohydrolase.
AN   Hydroxyatrazine ethylaminohydrolase.
AN   Hydroxyatrazine hydrolase.
CA   4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + H(2)O =
CA   N-isopropylammelide + ethylamine.
CC   -!- Involved in a pathway by which the herbicide atrazine, 2-chloro-4-
CC       (ethylamino)-6-(isopropylamino)-1,3,5-triazine, is degraded in
CC       bacteria via N-isopropylammelide, 2,4-dihydroxy-6-(isopropylamino)-
CC       1,3,5-triazine.
DR   P95442, ATZB_PSESD ;
//
ID   3.5.99.4
DE   N-isopropylammelide isopropylaminohydrolase.
CA   N-isopropylammelide + H(2)O = cyanuric acid + isopropylamine.
CC   -!- Involved in a pathway by which the herbicide atrazine, 2-chloro-4-
CC       (ethylamino)-6-(isopopylamino)-1,3,5-triazine, is degraded in
CC       bacteria via N-isopropylammelide, 2,4-dihydroxy-6-(isopropylamino)-
CC       1,3,5-triazine.
DR   O52063, ATZC_PSESD ;
//
ID   3.5.99.5
DE   2-aminomuconate deaminase.
CA   2-aminomuconate + H(2)O = 4-oxalocrotonate + NH(3).
CC   -!- Intermediate in the biodegradation of nitrobenzene by Pseudomonas
CC       pseudocaligenes JS45.
CC   -!- The reaction is spontaneous in acid conditions.
DR   P81593, 2AMD_PSEPS ;  Q9KWS2, AMND_PSESP ;
//
ID   3.5.99.6
DE   Glucosamine-6-phosphate deaminase.
AN   GlcN6P deaminase.
AN   Glucosamine phosphate deaminase.
AN   Glucosamine-6-phosphate isomerase.
AN   Phosphoglucosamine isomerase.
AN   Phosphoglucosaminisomerase.
CA   D-glucosamine 6-phosphate + H(2)O = D-fructose 6-phosphate + NH(3).
CC   -!- Isomerization of the aldose-ketose type converts the -CH(-NH(2))-CH=O
CC       group of glucosamine 6-phosphate into -C(=NH)-CH(2)-OH, forming
CC       2-deoxy-2-imino-D-arabino-hexitol which then hydrolyzes to yield
CC       fructose 6-phosphate and ammonia.
CC   -!- N-acetyl-D-glucosamine 6-phosphate, which is not broken down,
CC       activates the enzyme.
CC   -!- Formerly EC 5.3.1.10.
PR   PROSITE; PDOC00894;
DR   O31458, GAMA_BACSU ;  A4FV08, GNPI1_BOVIN;  O97439, GNPI1_GIAIN;
DR   P46926, GNPI1_HUMAN;  Q64422, GNPI1_MESAU;  O88958, GNPI1_MOUSE;
DR   Q5R8T8, GNPI1_PONAB;  Q17QL1, GNPI2_BOVIN;  O97440, GNPI2_GIAIN;
DR   Q8TDQ7, GNPI2_HUMAN;  Q9CRC9, GNPI2_MOUSE;  Q6PA43, GNPI2_XENLA;
DR   A4IHW6, GNPI2_XENTR;  Q16HW7, GNPI_AEDAE ;  Q5TNH5, GNPI_ANOGA ;
DR   Q9XVJ2, GNPI_CAEEL ;  Q54XK9, GNPI_DICDI ;  Q9VMP9, GNPI_DROME ;
DR   Q29NT9, GNPI_DROPS ;  Q04802, NAG1_CANAL ;  A9NEX8, NAGB_ACHLI ;
DR   A3N353, NAGB_ACTP2 ;  B3GZ06, NAGB_ACTP7 ;  B0BSS6, NAGB_ACTPJ ;
DR   A0KIG3, NAGB_AERHH ;  A4SPM2, NAGB_AERS4 ;  B6EN78, NAGB_ALISL ;
DR   A6TVP5, NAGB_ALKMQ ;  A8MIX7, NAGB_ALKOO ;  B8HAX3, NAGB_ARTCA ;
DR   A0JY49, NAGB_ARTS2 ;  A7Z975, NAGB_BACA2 ;  C3P761, NAGB_BACAA ;
DR   C3LIR9, NAGB_BACAC ;  A0RI59, NAGB_BACAH ;  Q81MH5, NAGB_BACAN ;
DR   B7JL33, NAGB_BACC0 ;  Q731P4, NAGB_BACC1 ;  B7IWG6, NAGB_BACC2 ;
DR   C1EQS8, NAGB_BACC3 ;  B7H945, NAGB_BACC4 ;  B7HN32, NAGB_BACC7 ;
DR   A7GS78, NAGB_BACCN ;  B9IWR7, NAGB_BACCQ ;  Q819D1, NAGB_BACCR ;
DR   Q635M6, NAGB_BACCZ ;  Q5LGU0, NAGB_BACFN ;  Q64XP2, NAGB_BACFR ;
DR   Q9KFQ8, NAGB_BACHD ;  Q6HEB2, NAGB_BACHK ;  A8FHS6, NAGB_BACP2 ;
DR   Q5WHY0, NAGB_BACSK ;  O35000, NAGB_BACSU ;  Q8A094, NAGB_BACTN ;
DR   A6L7Q8, NAGB_BACV8 ;  A9VFF7, NAGB_BACWK ;  C5BY94, NAGB_BEUC1 ;
DR   B3DQQ9, NAGB_BIFLD ;  Q8G4N5, NAGB_BIFLO ;  B7GQA1, NAGB_BIFLS ;
DR   Q7VR99, NAGB_BLOFL ;  Q0SP13, NAGB_BORAP ;  O30564, NAGB_BORBU ;
DR   B7J183, NAGB_BORBZ ;  Q662L3, NAGB_BORGA ;  B2RZL5, NAGB_BORHD ;
DR   C0ZJF8, NAGB_BREBN ;  B3PBV0, NAGB_CELJU ;  A8AJE0, NAGB_CITK8 ;
DR   Q97MK9, NAGB_CLOAB ;  A7FX73, NAGB_CLOB1 ;  C3L2N7, NAGB_CLOB6 ;
DR   A6M241, NAGB_CLOB8 ;  B2V163, NAGB_CLOBA ;  B2TL69, NAGB_CLOBB ;
DR   A5I5R9, NAGB_CLOBH ;  C1FV12, NAGB_CLOBJ ;  B1IKY4, NAGB_CLOBK ;
DR   A7GH51, NAGB_CLOBL ;  B1KZ07, NAGB_CLOBM ;  Q18AL0, NAGB_CLOD6 ;
DR   A0PYW1, NAGB_CLONN ;  Q0TML8, NAGB_CLOP1 ;  Q8XHP8, NAGB_CLOPE ;
DR   A9KIR8, NAGB_CLOPH ;  Q0SQB4, NAGB_CLOPS ;  Q890L6, NAGB_CLOTE ;
DR   Q487K8, NAGB_COLP3 ;  C3PJW6, NAGB_CORA7 ;  Q6NJ91, NAGB_CORDI ;
DR   Q8FMI6, NAGB_COREF ;  A4QH44, NAGB_CORGB ;  Q8NMD4, NAGB_CORGL ;
DR   C4LL80, NAGB_CORK4 ;  B1VI88, NAGB_CORU7 ;  C6C0A2, NAGB_DESAD ;
DR   A7ZJ60, NAGB_ECO24 ;  B7UKV0, NAGB_ECO27 ;  B7MFT4, NAGB_ECO45 ;
DR   B7L9L4, NAGB_ECO55 ;  P0A760, NAGB_ECO57 ;  B5YQM0, NAGB_ECO5E ;
DR   B7NMM9, NAGB_ECO7I ;  B7MPI3, NAGB_ECO81 ;  B7M5J6, NAGB_ECO8A ;
DR   C4ZWF4, NAGB_ECOBW ;  B1X6L1, NAGB_ECODH ;  A7ZXT7, NAGB_ECOHS ;
DR   A1A8T7, NAGB_ECOK1 ;  Q0TK13, NAGB_ECOL5 ;  Q8FJX7, NAGB_ECOL6 ;
DR   B1IY50, NAGB_ECOLC ;  P0A759, NAGB_ECOLI ;  B7N9S4, NAGB_ECOLU ;
DR   B6HYN6, NAGB_ECOSE ;  B1LLC0, NAGB_ECOSM ;  Q1REP9, NAGB_ECOUT ;
DR   C5BGA6, NAGB_EDWI9 ;  A4W844, NAGB_ENT38 ;  P59687, NAGB_ENTFA ;
DR   A7MQT6, NAGB_ENTS8 ;  Q6D7J9, NAGB_ERWCT ;  B2VBN5, NAGB_ERWT9 ;
DR   B7LKT5, NAGB_ESCF3 ;  B1YJ30, NAGB_EXIS2 ;  C4L2C5, NAGB_EXISA ;
DR   Q8REG1, NAGB_FUSNN ;  C5D3L0, NAGB_GEOSW ;  Q7VKN1, NAGB_HAEDU ;
DR   Q4QP46, NAGB_HAEI8 ;  A5UB10, NAGB_HAEIE ;  P44538, NAGB_HAEIN ;
DR   B8F877, NAGB_HAEPS ;  Q0I4B9, NAGB_HAES1 ;  B0UUN2, NAGB_HAES2 ;
DR   Q2S6X5, NAGB_HAHCH ;  B8D185, NAGB_HALOH ;  B5XZG9, NAGB_KLEP3 ;
DR   A6T6C1, NAGB_KLEP7 ;  Q5FHT1, NAGB_LACAC ;  Q033M5, NAGB_LACC3 ;
DR   Q1G817, NAGB_LACDA ;  Q047I3, NAGB_LACDB ;  A8YTN8, NAGB_LACH4 ;
DR   Q74HC4, NAGB_LACJO ;  Q9CFA8, NAGB_LACLA ;  A2RJR7, NAGB_LACLM ;
DR   Q02Y08, NAGB_LACLS ;  Q88ZS6, NAGB_LACPL ;  A5VKB2, NAGB_LACRD ;
DR   Q1WS60, NAGB_LACS1 ;  Q38YK9, NAGB_LACSS ;  B1MX39, NAGB_LEUCK ;
DR   Q03Z95, NAGB_LEUMM ;  Q92D64, NAGB_LISIN ;  C1L1M8, NAGB_LISMC ;
DR   Q721K9, NAGB_LISMF ;  B8DEH8, NAGB_LISMH ;  Q8Y8E7, NAGB_LISMO ;
DR   A0AH75, NAGB_LISW6 ;  B1HUU8, NAGB_LYSSC ;  P59686, NAGB_LYSSH ;
DR   Q65QE8, NAGB_MANSM ;  A6VVU9, NAGB_MARMS ;  Q6MSF4, NAGB_MYCMS ;
DR   Q8EWM7, NAGB_MYCPE ;  Q98QJ9, NAGB_MYCPU ;  A0QU88, NAGB_MYCS2 ;
DR   Q8ESL6, NAGB_OCEIH ;  Q04G36, NAGB_OENOB ;  A6LHV2, NAGB_PARD8 ;
DR   Q9CMF4, NAGB_PASMU ;  C6DBY4, NAGB_PECCP ;  Q03H91, NAGB_PEDPA ;
DR   Q7MB61, NAGB_PHOLL ;  B2RJ01, NAGB_PORG3 ;  Q7MW43, NAGB_PORGI ;
DR   Q6AAI8, NAGB_PROAC ;  B4ESJ0, NAGB_PROMH ;  Q3ID09, NAGB_PSEHT ;
DR   A1SS81, NAGB_PSYIN ;  Q7UVM5, NAGB_RHOBA ;  C1AW66, NAGB_RHOOB ;
DR   Q0SGH6, NAGB_RHOSR ;  B5EZC1, NAGB_SALA4 ;  A9MKA9, NAGB_SALAR ;
DR   Q57RQ0, NAGB_SALCH ;  B5FNB9, NAGB_SALDC ;  B5QWC8, NAGB_SALEP ;
DR   B5R824, NAGB_SALG2 ;  B4TB82, NAGB_SALHS ;  B4SYN7, NAGB_SALNS ;
DR   Q5PCH6, NAGB_SALPA ;  A9MUG8, NAGB_SALPB ;  C0PWA5, NAGB_SALPC ;
DR   B5BCC5, NAGB_SALPK ;  B4TPZ8, NAGB_SALSV ;  Q8Z8G0, NAGB_SALTI ;
DR   Q8ZQX7, NAGB_SALTY ;  A8GB41, NAGB_SERP5 ;  B0TTP5, NAGB_SHEHH ;
DR   A3QB39, NAGB_SHELP ;  A8FRI2, NAGB_SHESH ;  B1KFS0, NAGB_SHEWM ;
DR   B2TU53, NAGB_SHIB3 ;  Q324M6, NAGB_SHIBS ;  Q32IQ2, NAGB_SHIDS ;
DR   Q0T6S6, NAGB_SHIF8 ;  P59688, NAGB_SHIFL ;  Q3Z4C2, NAGB_SHISS ;
DR   A7WZ06, NAGB_STAA1 ;  A6TZ46, NAGB_STAA2 ;  Q2FJ71, NAGB_STAA3 ;
DR   Q2G0K8, NAGB_STAA8 ;  A5IQC3, NAGB_STAA9 ;  Q2YS95, NAGB_STAAB ;
DR   Q5HIA6, NAGB_STAAC ;  A6QEM2, NAGB_STAAE ;  P65512, NAGB_STAAM ;
DR   P99125, NAGB_STAAN ;  Q6GJA0, NAGB_STAAR ;  Q6GBR8, NAGB_STAAS ;
DR   A8YZR7, NAGB_STAAT ;  P65513, NAGB_STAAW ;  Q5HRH8, NAGB_STAEQ ;
DR   Q8CTR3, NAGB_STAES ;  Q4L9T8, NAGB_STAHJ ;  Q49VB6, NAGB_STAS1 ;
DR   Q3K1Q7, NAGB_STRA1 ;  P65514, NAGB_STRA3 ;  P65515, NAGB_STRA5 ;
DR   P59689, NAGB_STRAW ;  Q9K487, NAGB_STRCO ;  C0M970, NAGB_STRE4 ;
DR   B4U206, NAGB_STREM ;  A8AYK4, NAGB_STRGC ;  Q8DV70, NAGB_STRMU ;
DR   Q99Z50, NAGB_STRP1 ;  Q04JT5, NAGB_STRP2 ;  P0DC66, NAGB_STRP3 ;
DR   B5E5S3, NAGB_STRP4 ;  Q5XBG4, NAGB_STRP6 ;  C1C814, NAGB_STRP7 ;
DR   Q8P0E0, NAGB_STRP8 ;  A2RDX6, NAGB_STRPG ;  B1ICL5, NAGB_STRPI ;
DR   B8ZKX4, NAGB_STRPJ ;  Q97Q16, NAGB_STRPN ;  P0DC67, NAGB_STRPQ ;
DR   B5XM45, NAGB_STRPZ ;  Q8DPA1, NAGB_STRR6 ;  A4W0A3, NAGB_STRS2 ;
DR   C0MCU1, NAGB_STRS7 ;  A3CLX4, NAGB_STRSV ;  A4VU11, NAGB_STRSY ;
DR   Q03LS1, NAGB_STRTD ;  B9DWG4, NAGB_STRU0 ;  C1CF03, NAGB_STRZJ ;
DR   C1CLC3, NAGB_STRZP ;  C1CQU2, NAGB_STRZT ;  B0K934, NAGB_THEP3 ;
DR   B0K0J7, NAGB_THEPX ;  Q8R5T0, NAGB_THETN ;  C4L889, NAGB_TOLAT ;
DR   Q73QV6, NAGB_TREDE ;  A5F125, NAGB_VIBC3 ;  Q9KKS5, NAGB_VIBCH ;
DR   C3LWT7, NAGB_VIBCM ;  Q5E294, NAGB_VIBF1 ;  B5FBU7, NAGB_VIBFM ;
DR   A7N5W3, NAGB_VIBHB ;  Q87K60, NAGB_VIBPA ;  B7VTI0, NAGB_VIBSL ;
DR   Q8D4T9, NAGB_VIBVU ;  Q7MGE1, NAGB_VIBVY ;  A1JQE8, NAGB_YERE8 ;
DR   A7FKU3, NAGB_YERP3 ;  Q1C537, NAGB_YERPA ;  B2K8A2, NAGB_YERPB ;
DR   Q8ZDE1, NAGB_YERPE ;  A9R7S4, NAGB_YERPG ;  Q1CKN7, NAGB_YERPN ;
DR   A4TNY0, NAGB_YERPP ;  Q66DC7, NAGB_YERPS ;  B1JG88, NAGB_YERPY ;
//
ID   3.5.99.7
DE   1-aminocyclopropane-1-carboxylate deaminase.
AN   1-aminocyclopropane carboxylic acid deaminase.
AN   1-aminocyclopropane-1-carboxylate endolyase (deaminating).
AN   ACC deaminase.
CA   1-aminocyclopropane-1-carboxylate + H(2)O = 2-oxobutanoate + NH(3).
CF   Pyridoxal 5'-phosphate.
CC   -!- Its introduction has been used to make fruit ripening dependent on
CC       externally added ethylene, as it removes the substrate for endogenous
CC       ethylene formation.
CC   -!- Formerly EC 4.1.99.4.
DR   A1TVP2, 1A1D_ACIAC ;  B9MGI8, 1A1D_ACIET ;  B9JJB7, 1A1D_AGRRK ;
DR   B9K206, 1A1D_AGRVS ;  Q89XR6, 1A1D_BRAJA ;  A5EJ46, 1A1D_BRASB ;
DR   A4YUJ5, 1A1D_BRASO ;  B1YYR8, 1A1D_BURA4 ;  Q1BL32, 1A1D_BURCA ;
DR   B1K774, 1A1D_BURCC ;  A0AXI7, 1A1D_BURCH ;  B4EJA6, 1A1D_BURCJ ;
DR   Q0B569, 1A1D_BURCM ;  A9AQJ3, 1A1D_BURM1 ;  A3ME84, 1A1D_BURM7 ;
DR   A2RWH4, 1A1D_BURM9 ;  Q62CE3, 1A1D_BURMA ;  A1UVN3, 1A1D_BURMS ;
DR   A3P669, 1A1D_BURP0 ;  Q3JLQ0, 1A1D_BURP1 ;  A3NKK4, 1A1D_BURP6 ;
DR   B2TBV3, 1A1D_BURPP ;  Q63KN7, 1A1D_BURPS ;  Q390Z5, 1A1D_BURS3 ;
DR   Q2T6A1, 1A1D_BURTA ;  A4JKV8, 1A1D_BURVG ;  Q13ME5, 1A1D_BURXL ;
DR   Q5KMX3, 1A1D_CRYNJ ;  Q0K1H0, 1A1D_CUPNH ;  Q7M523, 1A1D_CYBSA ;
DR   Q9ZHW3, 1A1D_ENTCL ;  B8IP05, 1A1D_METNO ;  A2SLW2, 1A1D_METPP ;
DR   B0UGM0, 1A1D_METS4 ;  Q48KS9, 1A1D_PSE14 ;  Q51813, 1A1D_PSEFL ;
DR   Q5PWZ8, 1A1D_PSEPU ;  P30297, 1A1D_PSES0 ;  Q87YW7, 1A1D_PSESM ;
DR   Q4ZVH4, 1A1D_PSEU2 ;  Q00740, 1A1D_PSEUD ;  Q9V2L2, 1A1D_PYRAB ;
DR   Q8U4R3, 1A1D_PYRFU ;  O57809, 1A1D_PYRHO ;  B2UGM5, 1A1D_RALPJ ;
DR   Q8XS35, 1A1D_RALSO ;  Q98AM7, 1A1D_RHILO ;  Q93AG0, 1A1D_RHILV ;
DR   Q9AHF0, 1A1D_RHIRD ;  Q9URX3, 1A1D_SCHPO ;  Q9WY68, 1A1D_THEMA ;
DR   Q6J256, 1A1D_VARPD ;  C5CQC9, 1A1D_VARPS ;
//
ID   3.5.99.8
DE   5-nitroanthranilic acid aminohydrolase.
AN   5NAA deaminase.
CA   5-nitroanthranilate + H(2)O = 5-nitrosalicylate + NH(3).
CC   -!- The enzyme catalyzes the initial step in biodegradation of
CC       5-nitroanthranilic acid by Bradyrhizobium sp. strain JS329.
//
ID   3.6.1.1
DE   Inorganic diphosphatase.
AN   Diphosphate phosphohydrolase.
AN   Inorganic pyrophosphatase.
AN   Pyrophosphate phosphohydrolase.
CA   Diphosphate + H(2)O = 2 phosphate.
CC   -!- Specificity varies with the source and with the activating metal ion.
CC   -!- The enzyme from some sources may be identical with EC 3.1.3.1 or
CC       EC 3.1.3.9.
PR   PROSITE; PDOC00325;
DR   P31414, AVP1_ARATH ;  Q56ZN6, AVP2_ARATH ;  Q9FWR2, AVPX_ARATH ;
DR   Q06572, AVP_HORVU  ;  P21616, AVP_VIGRR  ;  Q8TJA9, HPPA1_METAC;
DR   Q8PYZ8, HPPA1_METMA;  Q2RIS7, HPPA1_MOOTA;  Q93AR8, HPPA1_MYCDI;
DR   Q93AS0, HPPA1_RHILT;  P60363, HPPA1_RHOPA;  Q8TJA8, HPPA2_METAC;
DR   Q8PYZ7, HPPA2_METMA;  Q2RLE0, HPPA2_MOOTA;  Q93AR9, HPPA2_MYCDI;
DR   Q93AS1, HPPA2_RHILT;  Q8KY01, HPPA2_RHOPA;  Q8UG67, HPPA_AGRT5 ;
DR   Q8VRZ1, HPPA_ANAMA ;  Q8A294, HPPA_BACTN ;  Q89K83, HPPA_BRAJA ;
DR   Q8YGH4, HPPA_BRUME ;  Q8G1E6, HPPA_BRUSU ;  Q3AFC6, HPPA_CARHZ ;
DR   Q9A8J0, HPPA_CAUCR ;  Q8VNW3, HPPA_CHLAA ;  Q8KDT8, HPPA_CHLTE ;
DR   Q8VNU8, HPPA_CHRVI ;  Q898Q9, HPPA_CLOTE ;  Q8RHJ2, HPPA_FUSNN ;
DR   Q8VNJ8, HPPA_HELCL ;  Q72Q29, HPPA_LEPIC ;  Q8F641, HPPA_LEPIN ;
DR   Q93NB7, HPPA_MYXXA ;  Q82TF3, HPPA_NITEU ;  Q8VRZ2, HPPA_OCHA4 ;
DR   Q8ZWI8, HPPA_PYRAE ;  Q983A3, HPPA_RHILO ;  Q8VRZ3, HPPA_RHIME ;
DR   Q8VPZ0, HPPA_RHIRD ;  O68460, HPPA_RHORT ;  Q82EJ8, HPPA_STRAW ;
DR   Q9X913, HPPA_STRCO ;  Q9S5X0, HPPA_THEMA ;  Q8RCX1, HPPA_THETN ;
DR   Q8PH20, HPPA_XANAC ;  Q8P5M6, HPPA_XANCP ;  Q9LXC9, IPYR1_ARATH;
DR   Q93Y52, IPYR1_CHLRE;  Q889M7, IPYR1_PSESM;  P21216, IPYR2_ARATH;
DR   Q949J1, IPYR2_CHLRE;  Q9H2U2, IPYR2_HUMAN;  Q91VM9, IPYR2_MOUSE;
DR   Q87WD6, IPYR2_PSESM;  P87118, IPYR2_SCHPO;  P28239, IPYR2_YEAST;
DR   Q9YBA5, IPYR_AERPE ;  Q8UC37, IPYR_AGRT5 ;  O67501, IPYR_AQUAE ;
DR   Q8GQS5, IPYR_AQUPY ;  Q757J8, IPYR_ASHGO ;  Q9KCG7, IPYR_BACHD ;
DR   P19514, IPYR_BACP3 ;  P51064, IPYR_BARBK ;  P37980, IPYR_BOVIN ;
DR   Q89WY0, IPYR_BRAJA ;  P65744, IPYR_BRUME ;  P65745, IPYR_BRUSU ;
DR   P57190, IPYR_BUCAI ;  Q8KA31, IPYR_BUCAP ;  P59417, IPYR_BUCBP ;
DR   Q18680, IPYR_CAEEL ;  Q9PHM9, IPYR_CAMJE ;  P83777, IPYR_CANAL ;
DR   Q6FRB7, IPYR_CANGA ;  Q9AC20, IPYR_CAUCR ;  Q821T4, IPYR_CHLCV ;
DR   Q9PLF1, IPYR_CHLMU ;  Q9Z6Y8, IPYR_CHLPN ;  B0B8Z8, IPYR_CHLT2 ;
DR   Q3KKS0, IPYR_CHLTA ;  B0BAM7, IPYR_CHLTB ;  O84777, IPYR_CHLTR ;
DR   Q8FMF8, IPYR_COREF ;  Q8NM79, IPYR_CORGL ;  P80887, IPYR_CYAPA ;
DR   Q6BWA5, IPYR_DEBHA ;  P19371, IPYR_DESVH ;  Q54PV8, IPYR_DICDI ;
DR   O77460, IPYR_DROME ;  P0A7B0, IPYR_ECO57 ;  Q8FAG0, IPYR_ECOL6 ;
DR   P0A7A9, IPYR_ECOLI ;  Q5B912, IPYR_EMENI ;  Q8SR69, IPYR_ENCCU ;
DR   P81987, IPYR_EUGGR ;  O05724, IPYR_GEOSE ;  O05545, IPYR_GLUOX ;
DR   Q7VPC0, IPYR_HAEDU ;  P44529, IPYR_HAEIN ;  Q9HSF3, IPYR_HALSA ;
DR   Q9ZLL5, IPYR_HELPJ ;  P56153, IPYR_HELPY ;  O23979, IPYR_HORVD ;
DR   Q15181, IPYR_HUMAN ;  P13998, IPYR_KLULA ;  O34955, IPYR_LEGPN ;
DR   Q6ACP7, IPYR_LEIXX ;  Q72MG4, IPYR_LEPIC ;  Q8EZ21, IPYR_LEPIN ;
DR   Q4R543, IPYR_MACFA ;  O48556, IPYR_MAIZE ;  Q8TMI3, IPYR_METAC ;
DR   Q8TVE2, IPYR_METKA ;  Q8PWY5, IPYR_METMA ;  O26363, IPYR_METTH ;
DR   Q9D819, IPYR_MOUSE ;  P65747, IPYR_MYCBO ;  P47593, IPYR_MYCGE ;
DR   O69540, IPYR_MYCLE ;  Q8EVW9, IPYR_MYCPE ;  P75250, IPYR_MYCPN ;
DR   Q98Q96, IPYR_MYCPU ;  P65746, IPYR_MYCTU ;  Q74MY6, IPYR_NANEQ ;
DR   Q9JVG3, IPYR_NEIMA ;  Q9K0G4, IPYR_NEIMB ;  Q6MVH7, IPYR_NEUCR ;
DR   P80562, IPYR_NOSS1 ;  P81988, IPYR_OCHDN ;  A2X8Q3, IPYR_ORYSI ;
DR   Q0DYB1, IPYR_ORYSJ ;  P57918, IPYR_PASMU ;  O13505, IPYR_PICPA ;
DR   Q6KZB3, IPYR_PICTO ;  O77392, IPYR_PLAF7 ;  Q5R8T6, IPYR_PONAB ;
DR   Q9HWZ6, IPYR_PSEAE ;  P0CAP8, IPYR_PSEAN ;  P58733, IPYR_PSEAO ;
DR   Q88QF6, IPYR_PSEPK ;  Q9UY24, IPYR_PYRAB ;  Q8U438, IPYR_PYRFU ;
DR   O59570, IPYR_PYRHO ;  Q5JIY3, IPYR_PYRKO ;  Q8XWX1, IPYR_RALSO ;
DR   Q98ER2, IPYR_RHILO ;  Q92LH1, IPYR_RHIME ;  Q9RGQ1, IPYR_RHORT ;
DR   P82992, IPYR_RHOVI ;  Q1RIN6, IPYR_RICBR ;  Q92H74, IPYR_RICCN ;
DR   Q4UKW0, IPYR_RICFE ;  Q9ZCW5, IPYR_RICPR ;  Q68WE9, IPYR_RICTY ;
DR   P65749, IPYR_SALTI ;  P65748, IPYR_SALTY ;  P19117, IPYR_SCHPO ;
DR   Q43187, IPYR_SOLTU ;  Q9X8I9, IPYR_STRCO ;  P50308, IPYR_SULAC ;
DR   Q97W51, IPYR_SULSO ;  Q974Y8, IPYR_SULTO ;  P80507, IPYR_SYNY3 ;
DR   P37981, IPYR_THEAC ;  Q8DHR2, IPYR_THEEB ;  P77992, IPYR_THELI ;
DR   P38576, IPYR_THET8 ;  Q979E6, IPYR_THEVO ;  Q9PQH6, IPYR_UREPA ;
DR   Q9KP34, IPYR_VIBCH ;  Q87SW1, IPYR_VIBPA ;  Q8DE89, IPYR_VIBVU ;
DR   Q7MPD2, IPYR_VIBVY ;  Q8D274, IPYR_WIGBR ;  Q8PH18, IPYR_XANAC ;
DR   Q8P5M4, IPYR_XANCP ;  P65750, IPYR_XYLFA ;  P65751, IPYR_XYLFT ;
DR   Q6C1T4, IPYR_YARLI ;  P00817, IPYR_YEAST ;  Q8ZB98, IPYR_YERPE ;
DR   Q9C0T9, IPYR_ZYGBA ;  Q0VD18, LHPP_BOVIN ;  A5PLK2, LHPP_DANRE ;
DR   Q9H008, LHPP_HUMAN ;  Q9D7I5, LHPP_MOUSE ;  Q5I0D5, LHPP_RAT   ;
DR   Q3B8E3, LHPP_XENLA ;  O29502, PPAC_ARCFU ;  A7ZAR2, PPAC_BACA2 ;
DR   C3PD52, PPAC_BACAA ;  C3LG25, PPAC_BACAC ;  Q81PH9, PPAC_BACAN ;
DR   B7JRU3, PPAC_BACC0 ;  Q736P6, PPAC_BACC1 ;  B7IJP9, PPAC_BACC2 ;
DR   C1EXV7, PPAC_BACC3 ;  B7HA46, PPAC_BACC4 ;  B7HUD5, PPAC_BACC7 ;
DR   A7GQ01, PPAC_BACCN ;  B9J353, PPAC_BACCQ ;  Q81CE5, PPAC_BACCR ;
DR   Q63AC7, PPAC_BACCZ ;  Q6HHR6, PPAC_BACHK ;  Q65E18, PPAC_BACLD ;
DR   P56948, PPAC_BACME ;  A8FJD5, PPAC_BACP2 ;  Q5WDX3, PPAC_BACSK ;
DR   P37487, PPAC_BACSU ;  A9VIG8, PPAC_BACWK ;  C0ZGL2, PPAC_BREBN ;
DR   Q97H75, PPAC_CLOAB ;  Q9RRB7, PPAC_DEIRA ;  Q834N3, PPAC_ENTFA ;
DR   B1YLU2, PPAC_EXIS2 ;  C4L0S9, PPAC_EXISA ;  Q5FK05, PPAC_LACAC ;
DR   Q1GAB5, PPAC_LACDA ;  Q04AP3, PPAC_LACDB ;  Q043J4, PPAC_LACGA ;
DR   A8YVH1, PPAC_LACH4 ;  Q74JD5, PPAC_LACJO ;  Q9CEM5, PPAC_LACLA ;
DR   Q88W32, PPAC_LACPL ;  Q92BR1, PPAC_LISIN ;  C1KV95, PPAC_LISMC ;
DR   Q71ZM2, PPAC_LISMF ;  B8DE62, PPAC_LISMH ;  Q8Y757, PPAC_LISMO ;
DR   A0AIQ0, PPAC_LISW6 ;  Q58025, PPAC_METJA ;  Q8CUT9, PPAC_OCEIH ;
DR   A7X451, PPAC_STAA1 ;  A6U325, PPAC_STAA2 ;  Q2FFH6, PPAC_STAA3 ;
DR   Q2FWY1, PPAC_STAA8 ;  A5IU87, PPAC_STAA9 ;  Q2YU53, PPAC_STAAB ;
DR   Q5HEK1, PPAC_STAAC ;  P65752, PPAC_STAAM ;  P65753, PPAC_STAAN ;
DR   Q6GFD7, PPAC_STAAR ;  Q6G813, PPAC_STAAS ;  A8Z2T4, PPAC_STAAT ;
DR   P65754, PPAC_STAAW ;  B9DMR8, PPAC_STACT ;  Q5HN17, PPAC_STAEQ ;
DR   Q8CNN7, PPAC_STAES ;  Q4L7N2, PPAC_STAHJ ;  Q49YW3, PPAC_STAS1 ;
DR   Q3K0B5, PPAC_STRA1 ;  Q8E4D4, PPAC_STRA3 ;  Q8DYS6, PPAC_STRA5 ;
DR   C0M7N7, PPAC_STRE4 ;  B4U4N8, PPAC_STREM ;  P95765, PPAC_STRGC ;
DR   O68579, PPAC_STRMU ;  P65757, PPAC_STRP1 ;  Q04JL5, PPAC_STRP2 ;
DR   P0DD14, PPAC_STRP3 ;  B5E699, PPAC_STRP4 ;  Q5XDN3, PPAC_STRP6 ;
DR   C1C8C3, PPAC_STRP7 ;  P65759, PPAC_STRP8 ;  A2RG81, PPAC_STRPG ;
DR   B1ICV4, PPAC_STRPI ;  B8ZLD4, PPAC_STRPJ ;  P65755, PPAC_STRPN ;
DR   P0DD15, PPAC_STRPQ ;  B2IR53, PPAC_STRPS ;  B5XJY9, PPAC_STRPZ ;
DR   P65756, PPAC_STRR6 ;  A4W395, PPAC_STRS2 ;  C0MGI9, PPAC_STRS7 ;
DR   A3CPM5, PPAC_STRSV ;  A4VWZ2, PPAC_STRSY ;  Q5M194, PPAC_STRT1 ;
DR   Q5M5T1, PPAC_STRT2 ;  Q03M65, PPAC_STRTD ;  B9DTT7, PPAC_STRU0 ;
DR   C1CFB5, PPAC_STRZJ ;  C1CLN3, PPAC_STRZP ;  C1CSF2, PPAC_STRZT ;
DR   Q9WZ56, PPAC_THEMA ;  B7GL49, PPAX_ANOFW ;  A7Z971, PPAX_BACA2 ;
DR   C3P0C8, PPAX_BACAA ;  C3LED0, PPAX_BACAC ;  A0RKU8, PPAX_BACAH ;
DR   Q6HQY9, PPAX_BACAN ;  B7JFI8, PPAX_BACC0 ;  Q72XV8, PPAX_BACC1 ;
DR   B7IPS5, PPAX_BACC2 ;  C1EZE2, PPAX_BACC3 ;  B7HEG2, PPAX_BACC4 ;
DR   B7HWY7, PPAX_BACC7 ;  B9J4R5, PPAX_BACCQ ;  Q815I8, PPAX_BACCR ;
DR   Q631J2, PPAX_BACCZ ;  Q9K6Y7, PPAX_BACHD ;  Q6HBC8, PPAX_BACHK ;
DR   A8FHS1, PPAX_BACP2 ;  Q9JMQ2, PPAX_BACSU ;  A9VQ75, PPAX_BACWK ;
DR   Q8XIY6, PPAX_CLOPE ;  Q928B2, PPAX_LISIN ;  C1KYP8, PPAX_LISMC ;
DR   Q71WU6, PPAX_LISMF ;  B8DBN0, PPAX_LISMH ;  Q8Y4G3, PPAX_LISMO ;
DR   A0ALG5, PPAX_LISW6 ;  Q8ENK3, PPAX_OCEIH ;  Q8R821, PPAX_THETN ;
DR   Q67YC0, PPSP1_ARATH;  Q9FZ62, PPSP2_ARATH;  Q9SU92, PPSP3_ARATH;
DR   Q5E9Y6, PRUNE_BOVIN;  Q86TP1, PRUNE_HUMAN;  Q8BIW1, PRUNE_MOUSE;
DR   Q6AYG3, PRUNE_RAT  ;
//
ID   3.6.1.2
DE   Trimetaphosphatase.
CA   Trimetaphosphate + H(2)O = triphosphate.
//
ID   3.6.1.3
DE   Adenosinetriphosphatase.
AN   Adenylpyrophosphatase.
AN   ATP monophosphatase.
AN   ATPase.
AN   Triphosphatase.
CA   ATP + H(2)O = ADP + phosphate.
CC   -!- Many enzymes previously listed under this number are now listed
CC       separately as EC 3.6.1.32 to EC 3.6.1.39.
CC   -!- The remaining enzymes, not separately listed on the basis of some
CC       function coupled with hydrolyzes of ATP, include enzymes dependent on
CC       Ca(2+), Mg(2+), anions, H(+) or DNA.
CC   -!- Formerly EC 3.6.1.4.
DR   Q6PL18, ATAD2_HUMAN;  Q8CDM1, ATAD2_MOUSE;  Q5RDX4, ATAD2_PONAB;
DR   Q6FU50, LHS1_CANGA ;  P36016, LHS1_YEAST ;  Q86567, MREP_BBTVA ;
DR   Q9WIJ5, MREP_FBNY1 ;  O39828, MREP_FBNY2 ;  Q9IR51, MREP_MDV1  ;
DR   Q9ICP7, MREP_SCSVF ;  Q9Z034, REP10_MDV1 ;  O91254, REP1_FBNY1 ;
DR   Q66862, REP1_FBNY2 ;  Q9Z0D5, REP1_MDV1  ;  Q9Z0D4, REP2_MDV1  ;
DR   Q87009, REP2_SCSVF ;  Q9Z0D3, REP3_MDV1  ;  Q87013, REP6_SCSVF ;
DR   Q9WIK0, REP7_FBNY1 ;  O91250, REP7_FBNY2 ;  Q9WIK2, REP9_FBNY1 ;
DR   P0CAX6, REP9_FBNY2 ;  Q9YUD3, REP_BFDV   ;  Q912W1, REP_CACV   ;
DR   Q91EK3, REP_GOCV   ;  Q805H4, REP_PCV1C  ;  Q8BB16, REP_PCV2   ;
DR   Q9IG45, REP_PICV   ;
//
ID   3.6.1.4
DE   Transferred entry: 3.6.1.3.
//
ID   3.6.1.5
DE   Apyrase.
AN   Adenosine diphosphatase.
AN   ADPase.
AN   ATP-diphosphatase.
AN   ATP-diphosphohydrolase.
CA   ATP + 2 H(2)O = AMP + 2 phosphate.
CF   Calcium.
CC   -!- Also acts on ADP, and on other nucleoside triphosphates and
CC       diphosphates.
CC   -!- Most of the ecto-ATPases occurring on the cell surface and
CC       hydrolyzing extracellular nucleoside triphosphates and diphosphates
CC       belong to this enzyme family.
PR   PROSITE; PDOC00952;
DR   P50635, APY_AEDAE  ;  O96559, APY_CIMLE  ;  P80595, APY_SOLTU  ;
DR   O18956, ENTP1_BOVIN;  P49961, ENTP1_HUMAN;  P55772, ENTP1_MOUSE;
DR   Q9MYU4, ENTP1_PIG  ;  P97687, ENTP1_RAT  ;  O75355, ENTP3_HUMAN;
DR   A0JND9, ENTP8_BOVIN;  O93295, ENTP8_CHICK;  Q5MY95, ENTP8_HUMAN;
DR   Q8K0L2, ENTP8_MOUSE;  Q5DRK1, ENTP8_RAT  ;  Q9USP2, YND1_SCHPO ;
DR   P40009, YND1_YEAST ;
//
ID   3.6.1.6
DE   Nucleoside-diphosphatase.
CA   A nucleoside diphosphate + H(2)O = a nucleotide + phosphate.
CC   -!- Acts on IDP, GDP, UDP and also on D-ribose 5-diphosphate.
DR   Q8WVQ1, CANT1_HUMAN;  Q8VCF1, CANT1_MOUSE;  Q8K4Y7, CANT1_RAT  ;
DR   Q9Y227, ENTP4_HUMAN;  Q9DBT4, ENTP4_MOUSE;  D2GZV9, ENTP5_AILME;
DR   E1BPW0, ENTP5_BOVIN;  E1C1L6, ENTP5_CHICK;  O75356, ENTP5_HUMAN;
DR   Q9QYC8, ENTP5_MESAU;  Q9WUZ9, ENTP5_MOUSE;  Q6P6S9, ENTP5_RAT  ;
DR   O75354, ENTP6_HUMAN;  Q9ER31, ENTP6_RAT  ;  Q617Y0, MIG23_CAEBR;
DR   Q21815, MIG23_CAEEL;  Q9XU84, UDA1_CAEEL ;
//
ID   3.6.1.7
DE   Acylphosphatase.
AN   Acylphosphate phosphohydrolase.
CA   An acylphosphate + H(2)O = a carboxylate + phosphate.
PR   PROSITE; PDOC00136;
DR   P41500, ACYP1_BOVIN;  P07032, ACYP1_CHICK;  P56544, ACYP1_DROME;
DR   P07311, ACYP1_HUMAN;  P56376, ACYP1_MOUSE;  P24540, ACYP1_PIG  ;
DR   Q8Y2W3, ACYP1_RALSO;  Q6DE05, ACYP1_XENLA;  Q28FK7, ACYP1_XENTR;
DR   P14620, ACYP2_ANAPL;  P07033, ACYP2_BOVIN;  P35744, ACYP2_CAVPO;
DR   P07031, ACYP2_CHICK;  Q9VF36, ACYP2_DROME;  P00818, ACYP2_HORSE;
DR   P14621, ACYP2_HUMAN;  P00821, ACYP2_MELGA;  P56375, ACYP2_MOUSE;
DR   P00819, ACYP2_PIG  ;  P00820, ACYP2_RABIT;  Q8XU24, ACYP2_RALSO;
DR   P35745, ACYP2_RAT  ;  Q5EBE1, ACYP2_XENTR;  B0C8Q6, ACYP_ACAM1 ;
DR   Q1IKJ2, ACYP_ACIBL ;  A0LV84, ACYP_ACIC1 ;  A5G1Y9, ACYP_ACICJ ;
DR   A1WDC8, ACYP_ACISJ ;  A3MYL5, ACYP_ACTP2 ;  A6VN24, ACYP_ACTSZ ;
DR   A0KKF3, ACYP_AERHH ;  Q9YBK7, ACYP_AERPE ;  A4SML6, ACYP_AERS4 ;
DR   Q0VPA8, ACYP_ALCBS ;  Q0ABB1, ACYP_ALHEH ;  Q2INT8, ACYP_ANADE ;
DR   A7H8A3, ACYP_ANADF ;  Q3M4K7, ACYP_ANAVT ;  O29440, ACYP_ARCFU ;
DR   A1R3U5, ACYP_ARTAT ;  A0JTE5, ACYP_ARTS2 ;  A8I5S8, ACYP_AZOC5 ;
DR   A1KAG5, ACYP_AZOSB ;  A7Z2E2, ACYP_BACA2 ;  Q65MJ1, ACYP_BACLD ;
DR   A8FAY5, ACYP_BACP2 ;  O35031, ACYP_BACSU ;  Q8G4T0, ACYP_BIFLO ;
DR   Q2KTJ9, ACYP_BORA1 ;  Q0SL54, ACYP_BORAP ;  Q7WDK7, ACYP_BORBR ;
DR   O50977, ACYP_BORBU ;  Q6ASQ0, ACYP_BORGA ;  Q7W2L1, ACYP_BORPA ;
DR   Q89JL8, ACYP_BRAJA ;  Q1BJL9, ACYP_BURCA ;  A0B3Q5, ACYP_BURCH ;
DR   Q0B602, ACYP_BURCM ;  A3MGM0, ACYP_BURM7 ;  Q62A02, ACYP_BURMA ;
DR   Q3JJ17, ACYP_BURP1 ;  A3NNW7, ACYP_BURP6 ;  Q63IA7, ACYP_BURPS ;
DR   Q39BD4, ACYP_BURS3 ;  Q2T321, ACYP_BURTA ;  A4JK94, ACYP_BURVG ;
DR   Q13J37, ACYP_BURXL ;  A8MC09, ACYP_CALMQ ;  A9WAI7, ACYP_CHLAA ;
DR   Q8KG42, ACYP_CHLTE ;  Q1QWG7, ACYP_CHRSD ;  A8AIA9, ACYP_CITK8 ;
DR   Q97FB0, ACYP_CLOAB ;  A6M163, ACYP_CLOB8 ;  Q0TNY8, ACYP_CLOP1 ;
DR   Q8XIZ0, ACYP_CLOPE ;  Q0SRK7, ACYP_CLOPS ;  Q482P4, ACYP_COLP3 ;
DR   Q6NGH6, ACYP_CORDI ;  Q8FP19, ACYP_COREF ;  A4QFD3, ACYP_CORGB ;
DR   Q8NNW4, ACYP_CORGL ;  A9KH12, ACYP_COXBN ;  Q83AB0, ACYP_COXBU ;
DR   Q0K6H7, ACYP_CUPNH ;  Q46WU4, ACYP_CUPPJ ;  Q47GU0, ACYP_DECAR ;
DR   Q3Z7Q6, ACYP_DEHE1 ;  A5FQM9, ACYP_DEHSB ;  Q3ZXY7, ACYP_DEHSC ;
DR   Q1J123, ACYP_DEIGD ;  Q9RVU3, ACYP_DEIRA ;  Q30YK6, ACYP_DESDG ;
DR   Q72CU1, ACYP_DESVH ;  A1VEL6, ACYP_DESVV ;  P0AB66, ACYP_ECO57 ;
DR   A1A9N7, ACYP_ECOK1 ;  Q8FJ70, ACYP_ECOL6 ;  P0AB65, ACYP_ECOLI ;
DR   A4W8Y0, ACYP_ENT38 ;  Q831U6, ACYP_ENTFA ;  A7ME43, ACYP_ENTS8 ;
DR   Q6D6C4, ACYP_ERWCT ;  A7HMJ7, ACYP_FERNB ;  Q0RDN6, ACYP_FRAAA ;
DR   Q2J6Z2, ACYP_FRASC ;  Q5L2Y4, ACYP_GEOKA ;  Q39S27, ACYP_GEOMG ;
DR   Q74ES0, ACYP_GEOSL ;  A4IKB1, ACYP_GEOTN ;  A5GA97, ACYP_GEOUR ;
DR   Q7NE87, ACYP_GLOVI ;  Q0BUL9, ACYP_GRABC ;  Q2SDN9, ACYP_HAHCH ;
DR   A1WUX3, ACYP_HALHL ;  Q5V2Y4, ACYP_HALMA ;  Q18K02, ACYP_HALWD ;
DR   Q7VJW4, ACYP_HELHP ;  A6T769, ACYP_KLEP7 ;  Q03RM5, ACYP_LACBA ;
DR   Q038C3, ACYP_LACC3 ;  Q041W5, ACYP_LACGA ;  Q74ID8, ACYP_LACJO ;
DR   Q9CHW2, ACYP_LACLA ;  Q88WR7, ACYP_LACPL ;  Q1WUK1, ACYP_LACS1 ;
DR   Q38VU9, ACYP_LACSS ;  Q5X427, ACYP_LEGPA ;  A5ID38, ACYP_LEGPC ;
DR   Q5ZUC1, ACYP_LEGPH ;  Q5WVG7, ACYP_LEGPL ;  Q72ML5, ACYP_LEPIC ;
DR   Q8EZ81, ACYP_LEPIN ;  Q03VF5, ACYP_LEUMM ;  Q92BX4, ACYP_LISIN ;
DR   Q71ZT9, ACYP_LISMF ;  Q8Y7A7, ACYP_LISMO ;  A0AII3, ACYP_LISW6 ;
DR   Q65UA8, ACYP_MANSM ;  A1TZV5, ACYP_MARAV ;  Q12WD5, ACYP_METBU ;
DR   Q60AX4, ACYP_METCA ;  Q2FNJ0, ACYP_METHJ ;  A4YHE5, ACYP_METS5 ;
DR   A0B571, ACYP_METTP ;  Q2RJ59, ACYP_MOOTA ;  A0QJ63, ACYP_MYCA1 ;
DR   P69418, ACYP_MYCBO ;  A1KMR7, ACYP_MYCBP ;  Q73VM2, ACYP_MYCPA ;
DR   A0QV24, ACYP_MYCS2 ;  A3PXU3, ACYP_MYCSJ ;  A1UED9, ACYP_MYCSK ;
DR   Q1BAM3, ACYP_MYCSS ;  A5U6S8, ACYP_MYCTA ;  P69419, ACYP_MYCTU ;
DR   A1T739, ACYP_MYCVP ;  Q1D0P6, ACYP_MYXXD ;  Q3IPI5, ACYP_NATPD ;
DR   Q1QLD8, ACYP_NITHX ;  Q3JCP6, ACYP_NITOC ;  Q3SRU5, ACYP_NITWN ;
DR   Q5YS19, ACYP_NOCFA ;  A1SPV1, ACYP_NOCSJ ;  Q8YYH3, ACYP_NOSS1 ;
DR   Q8ELH4, ACYP_OCEIH ;  Q9CNN1, ACYP_PASMU ;  Q03G94, ACYP_PEDPA ;
DR   Q3A2F4, ACYP_PELCD ;  A5D1R6, ACYP_PELTS ;  A9BHQ1, ACYP_PETMO ;
DR   Q7N5Z2, ACYP_PHOLL ;  Q6LQ38, ACYP_PHOPR ;  Q6L2I0, ACYP_PICTO ;
DR   A1VW83, ACYP_POLNA ;  A6VA18, ACYP_PSEA7 ;  Q9I504, ACYP_PSEAE ;
DR   A1SWQ8, ACYP_PSYIN ;  Q9UY47, ACYP_PYRAB ;  Q8ZXK6, ACYP_PYRAE ;
DR   A4WHP6, ACYP_PYRAR ;  A3MU96, ACYP_PYRCJ ;  Q8U414, ACYP_PYRFU ;
DR   P84142, ACYP_PYRHO ;  A1RU25, ACYP_PYRIL ;  Q5JDG7, ACYP_PYRKO ;
DR   Q1LIH0, ACYP_RALME ;  Q2K7M8, ACYP_RHIEC ;  Q1MFT8, ACYP_RHIL3 ;
DR   Q985C8, ACYP_RHILO ;  Q92TK9, ACYP_RHIME ;  Q21YG7, ACYP_RHOFD ;
DR   Q07L15, ACYP_RHOP5 ;  Q6N510, ACYP_RHOPA ;  Q211P4, ACYP_RHOPB ;
DR   Q135C2, ACYP_RHOPS ;  Q2RQZ4, ACYP_RHORT ;  Q0S2D6, ACYP_RHOSR ;
DR   A5UQ40, ACYP_ROSS1 ;  Q1AXW6, ACYP_RUBXD ;  Q21FZ9, ACYP_SACD2 ;
DR   A4FMH0, ACYP_SACEN ;  A9MHS1, ACYP_SALAR ;  Q5PGB8, ACYP_SALPA ;
DR   Q2S0V7, ACYP_SALRD ;  Q8XGT4, ACYP_SALTI ;  Q7CQS9, ACYP_SALTY ;
DR   A8GCM9, ACYP_SERP5 ;  A1S579, ACYP_SHEAM ;  Q8EEW0, ACYP_SHEON ;
DR   Q31YN1, ACYP_SHIBS ;  Q83LL9, ACYP_SHIFL ;  A6UH73, ACYP_SINMW ;
DR   Q2NU62, ACYP_SODGM ;  Q01Q91, ACYP_SOLUE ;  A9FGA8, ACYP_SORC5 ;
DR   A5VFP2, ACYP_SPHWW ;  A7X283, ACYP_STAA1 ;  Q2FH34, ACYP_STAA3 ;
DR   Q2FYM9, ACYP_STAA8 ;  Q2YY14, ACYP_STAAB ;  Q5HG16, ACYP_STAAC ;
DR   A6QGV5, ACYP_STAAE ;  Q99U83, ACYP_STAAM ;  Q7A5P1, ACYP_STAAN ;
DR   Q6GH04, ACYP_STAAR ;  Q6G9F7, ACYP_STAAS ;  Q7A0X1, ACYP_STAAW ;
DR   Q4L6A9, ACYP_STAHJ ;  Q82JU5, ACYP_STRAW ;  Q9ZBQ3, ACYP_STRCO ;
DR   Q4J8X9, ACYP_SULAC ;  Q97ZL0, ACYP_SULSO ;  Q971Z4, ACYP_SULTO ;
DR   Q2LTM9, ACYP_SYNAS ;  A0LI66, ACYP_SYNFM ;  Q2JNH2, ACYP_SYNJB ;
DR   A5GM25, ACYP_SYNPW ;  A5GS00, ACYP_SYNR3 ;  Q0IBG0, ACYP_SYNS3 ;
DR   Q3AYW4, ACYP_SYNS9 ;  Q3AIC0, ACYP_SYNSC ;  Q47S76, ACYP_THEFY ;
DR   A8F4E8, ACYP_THELT ;  Q9X1Q0, ACYP_THEMA ;  A5IM19, ACYP_THEP1 ;
DR   A1RZ22, ACYP_THEPD ;  Q72L64, ACYP_THET2 ;  Q5SKS6, ACYP_THET8 ;
DR   Q8R961, ACYP_THETN ;  Q97CT1, ACYP_THEVO ;  Q3SKG9, ACYP_THIDA ;
DR   Q73PK2, ACYP_TREDE ;  Q0W6M8, ACYP_UNCMA ;  A5F8G9, ACYP_VIBC3 ;
DR   Q9KSA4, ACYP_VIBCH ;  Q5E4P9, ACYP_VIBF1 ;  Q87P91, ACYP_VIBPA ;
DR   Q8D994, ACYP_VIBVU ;  Q7ML77, ACYP_VIBVY ;  Q8PNV0, ACYP_XANAC ;
DR   Q3BX12, ACYP_XANC5 ;  Q4URB1, ACYP_XANC8 ;  Q8PC73, ACYP_XANCP ;
DR   Q2NZV7, ACYP_XANOM ;  Q5GWQ4, ACYP_XANOR ;  A1JMX0, ACYP_YERE8 ;
DR   A7FJR7, ACYP_YERP3 ;  Q1CGL9, ACYP_YERPN ;  Q66CD9, ACYP_YERPS ;
//
ID   3.6.1.8
DE   ATP diphosphatase.
AN   ATP pyrophosphatase.
AN   ATPase.
CA   ATP + H(2)O = AMP + diphosphate.
CC   -!- Also acts on ITP, GTP, CTP and UTP.
DR   P0AEY4, MAZG_ECO57 ;  P0AEY3, MAZG_ECOLI ;  P44723, MAZG_HAEIN ;
DR   A0R3C4, MAZG_MYCS2 ;  P96379, MAZG_MYCTU ;
//
ID   3.6.1.9
DE   Nucleotide diphosphatase.
AN   Nucleotide pyrophosphatase.
CA   A dinucleotide + H(2)O = 2 mononucleotides.
CC   -!- Substrates include NAD(+), NADP(+), FAD, CoA and also ATP and ADP.
DR   P22413, ENPP1_HUMAN;  P06802, ENPP1_MOUSE;  Q924C3, ENPP1_RAT  ;
DR   P15396, ENPP3_BOVIN;  O14638, ENPP3_HUMAN;  Q6DYE8, ENPP3_MOUSE;
DR   Q5R5M5, ENPP3_PONAB;  P97675, ENPP3_RAT  ;  P25353, NPP1_YEAST ;
DR   P39997, NPP2_YEAST ;
//
ID   3.6.1.10
DE   Endopolyphosphatase.
AN   Metaphosphatase.
AN   Polyphosphatase.
AN   Polyphosphate depolymerase.
CA   Polyphosphate + n H(2)O = (n+1) oligophosphate.
CC   -!- The product contains 4 or 5 phosphate residues.
DR   Q756F2, PPN1_ASHGO ;  Q6FMQ0, PPN1_CANGA ;  Q5KH67, PPN1_CRYNJ ;
DR   Q6BKG0, PPN1_DEBHA ;  Q6CWT7, PPN1_KLULA ;  Q9P3S1, PPN1_NEUCR ;
DR   Q9C1W8, PPN1_SCHPO ;  Q6CEE7, PPN1_YARLI ;  Q04119, PPN1_YEAST ;
//
ID   3.6.1.11
DE   Exopolyphosphatase.
AN   Exopolypase.
AN   Metaphosphatase.
CA   (Polyphosphate)(n) + H(2)O = (polyphosphate)(n-1) + phosphate.
DR   Q04119, PPN1_YEAST ;  O14094, PPX1_SCHPO ;  P38698, PPX1_YEAST ;
DR   P0AFL8, PPX_ECO57  ;  P0AFL7, PPX_ECOL6  ;  P0AFL6, PPX_ECOLI  ;
DR   P44828, PPX_HAEIN  ;  Q9ZN70, PPX_PSEAE  ;  P0A270, PPX_SALTI  ;
DR   P0A269, PPX_SALTY  ;  Q9KU08, PPX_VIBCH  ;  A8ANV8, SURE_CITK8 ;
DR   A7ZQI8, SURE_ECO24 ;  B7UHG3, SURE_ECO27 ;  B7MKL8, SURE_ECO45 ;
DR   B7LEG2, SURE_ECO55 ;  P0A842, SURE_ECO57 ;  B5Z3A6, SURE_ECO5E ;
DR   B7NT88, SURE_ECO7I ;  B7MZ45, SURE_ECO81 ;  B7LXF6, SURE_ECO8A ;
DR   C4ZZP8, SURE_ECOBW ;  B1XCS0, SURE_ECODH ;  A8A3M3, SURE_ECOHS ;
DR   A1AET8, SURE_ECOK1 ;  Q0TEB4, SURE_ECOL5 ;  P0A841, SURE_ECOL6 ;
DR   B1IUT5, SURE_ECOLC ;  P0A840, SURE_ECOLI ;  B7N6X4, SURE_ECOLU ;
DR   B6I6D4, SURE_ECOSE ;  Q1R7U7, SURE_ECOUT ;  C5BGI8, SURE_EDWI9 ;
DR   A4WDU9, SURE_ENT38 ;  A7MJ60, SURE_ENTS8 ;  B2VG26, SURE_ERWT9 ;
DR   B7LWJ1, SURE_ESCF3 ;  B5XV37, SURE_KLEP3 ;  Q7N8K4, SURE_PHOLL ;
DR   B4F224, SURE_PROMH ;  A9MF31, SURE_SALAR ;  Q57KJ7, SURE_SALCH ;
DR   B5QW15, SURE_SALEP ;  B5RDQ0, SURE_SALG2 ;  B4T454, SURE_SALNS ;
DR   Q5PEG4, SURE_SALPA ;  A9N2D0, SURE_SALPB ;  B5BEY1, SURE_SALPK ;
DR   B4TTV8, SURE_SALSV ;  P66882, SURE_SALTI ;  P66881, SURE_SALTY ;
DR   A8G9Z5, SURE_SERP5 ;  B2TZI7, SURE_SHIB3 ;  Q31XA6, SURE_SHIBS ;
DR   Q32CI6, SURE_SHIDS ;  Q0T1H5, SURE_SHIF8 ;  Q83JY2, SURE_SHIFL ;
DR   Q3YYB8, SURE_SHISS ;  Q2NVM2, SURE_SODGM ;  Q8D2P7, SURE_WIGBR ;
DR   A1JJT7, SURE_YERE8 ;  A7FLX5, SURE_YERP3 ;  Q1C475, SURE_YERPA ;
DR   B2K580, SURE_YERPB ;  Q8ZBP9, SURE_YERPE ;  A9R116, SURE_YERPG ;
DR   Q1CLR3, SURE_YERPN ;  A4TQ00, SURE_YERPP ;  Q66EC0, SURE_YERPS ;
DR   B1JJF5, SURE_YERPY ;
//
ID   3.6.1.12
DE   dCTP diphosphatase.
AN   dCTP pyrophosphatase.
AN   dCTPase.
AN   Deoxy-CTPase.
AN   Deoxycytidine-triphosphatase.
CA   dCTP + H(2)O = dCMP + diphosphate.
CC   -!- Also hydrolyzes dCDP to dCMP and phosphate.
DR   Q32KY6, DCTP1_BOVIN;  Q9H773, DCTP1_HUMAN;  Q9QY93, DCTP1_MOUSE;
DR   Q91VC0, DCTP1_RAT  ;  Q94MV8, VG56_BPLZ5 ;  P39262, VG56_BPT4  ;
//
ID   3.6.1.13
DE   ADP-ribose diphosphatase.
AN   Adenosine diphosphoribose pyrophosphatase.
AN   ADP-ribose phosphohydrolase.
AN   ADP-ribose pyrophosphatase.
AN   ADPR-PPase.
CA   ADP-ribose + H(2)O = AMP + D-ribose 5-phosphate.
DR   P54570, ADPP_BACSU ;  P83843, ADPP_ECO57 ;  P83842, ADPP_ECOL6 ;
DR   Q93K97, ADPP_ECOLI ;  P44684, ADPP_HAEIN ;  Q58549, ADPP_METJA ;
DR   P83844, ADPP_SHIFL ;  Q01976, ADPP_YEAST ;  A7YY53, ADPRM_BOVIN;
DR   Q7T291, ADPRM_DANRE;  Q3LIE5, ADPRM_HUMAN;  Q99KS6, ADPRM_MOUSE;
DR   Q5M886, ADPRM_RAT  ;  Q7T0Q0, ADPRM_XENLA;  Q66JJ3, ADPRM_XENTR;
DR   Q6NPD7, NUD10_ARATH;  P93740, NUD23_ARATH;  Q94B74, NUDT2_ARATH;
DR   Q9LE73, NUDT4_ARATH;  Q9UKK9, NUDT5_HUMAN;  Q9JKX6, NUDT5_MOUSE;
DR   Q5RCY2, NUDT5_PONAB;  Q6AY63, NUDT5_RAT  ;  Q9SJC4, NUDT6_ARATH;
DR   Q9SU14, NUDT7_ARATH;  Q9BW91, NUDT9_HUMAN;  Q8BVU5, NUDT9_MOUSE;
DR   Q5XIG0, NUDT9_RAT  ;  O94759, TRPM2_HUMAN;  Q91YD4, TRPM2_MOUSE;
//
ID   3.6.1.14
DE   Adenosine-tetraphosphatase.
CA   Adenosine 5'-tetraphosphate + H(2)O = ATP + phosphate.
CC   -!- Also acts on inosine tetraphosphate and tripolyphosphate but shows
CC       little or no activity with other nucleotides or polyphosphates.
//
ID   3.6.1.15
DE   Nucleoside-triphosphatase.
AN   NTPase.
AN   Nucleoside 5-triphosphatase.
AN   Nucleoside triphosphate hydrolase.
AN   Nucleoside triphosphate phosphohydrolase.
AN   Nucleoside-5-triphosphate phosphohydrolase.
CA   NTP + H(2)O = NDP + phosphate.
CC   -!- Also hydrolyzes other nucleoside triphosphates, diphosphates,
CC       thiamine diphosphate and FAD.
PR   PROSITE; PDOC00952;
DR   P29814, NTP1_AMEPV ;  Q18411, NTP1_CAEEL ;  P24486, NTP1_CBEPV ;
DR   O91729, NTP1_CFEPV ;  O72907, NTP1_FOWPN ;  O37319, NTP1_HAEPV ;
DR   Q98267, NTP1_MCV1  ;  Q9YW39, NTP1_MSEPV ;  Q9Q8L4, NTP1_MYXVL ;
DR   Q9Q8Z2, NTP1_RFVKA ;  Q08513, NTP1_SWPVK ;  Q27893, NTP1_TOXGO ;
DR   O57214, NTP1_VACCA ;  P20637, NTP1_VACCC ;  P05807, NTP1_VACCW ;
DR   P33066, NTP1_VAR67 ;  Q9QB93, NTP1_YMTV5 ;  Q27895, NTP2_TOXGO ;
DR   P52913, NTP4_TOXGO ;  P52914, NTPA_PEA   ;  Q1LZ78, NTPCR_BOVIN;
DR   Q9BSD7, NTPCR_HUMAN;  Q9CQA9, NTPCR_MOUSE;  Q9YDY8, NTPTH_AERPE;
DR   O67322, NTPTH_AQUAE;  O29444, NTPTH_ARCFU;  A8MB70, NTPTH_CALMQ;
DR   A2BL86, NTPTH_HYPBU;  A8ABE2, NTPTH_IGNH4;  B1L726, NTPTH_KORCO;
DR   Q8TKK3, NTPTH_METAC;  Q467J7, NTPTH_METBF;  Q58954, NTPTH_METJA;
DR   Q8TX49, NTPTH_METKA;  A4YEP4, NTPTH_METS5;  O27140, NTPTH_METTH;
DR   B2A6V4, NTPTH_NATTJ;  Q6L2J8, NTPTH_PICTO;  Q9UZ81, NTPTH_PYRAB;
DR   Q8ZTE6, NTPTH_PYRAE;  A4WLK1, NTPTH_PYRAR;  A3MX10, NTPTH_PYRCJ;
DR   Q8TH18, NTPTH_PYRFU;  O58522, NTPTH_PYRHO;  A1RRZ4, NTPTH_PYRIL;
DR   Q5JF42, NTPTH_PYRKO;  A3DNY5, NTPTH_STAMF;  Q4JCN8, NTPTH_SULAC;
DR   Q97WP0, NTPTH_SULSO;  Q96YL7, NTPTH_SULTO;  Q9HJH0, NTPTH_THEAC;
DR   Q9WXP3, NTPTH_THEMA;  B1Y9N2, NTPTH_THENV;  A5IL32, NTPTH_THEP1;
DR   A1RYX5, NTPTH_THEPD;  B1LAB2, NTPTH_THESQ;  Q97AR1, NTPTH_THEVO;
DR   P11125, P4_BPPH6   ;  Q9YLS4, POLG_AEVCA ;  Q6WQ42, POLG_AEVL2 ;
DR   Q6R325, POLG_AEVVR ;  Q288N7, POLG_BECN1 ;  Q8JN60, POLG_BECNB ;
DR   P12915, POLG_BOVEV ;  Q96662, POLG_BVDVC ;  P19711, POLG_BVDVN ;
DR   Q01499, POLG_BVDVS ;  Q8V736, POLG_CACV4 ;  P19712, POLG_CSFVA ;
DR   P21530, POLG_CSFVB ;  Q65900, POLG_CX16G ;  Q9QF31, POLG_CX16T ;
DR   P22055, POLG_CXA21 ;  P36290, POLG_CXA24 ;  P21404, POLG_CXA9  ;
DR   P08291, POLG_CXB1J ;  Q9YLG5, POLG_CXB2O ;  P03313, POLG_CXB3N ;
DR   Q66282, POLG_CXB3W ;  Q86887, POLG_CXB4E ;  P08292, POLG_CXB4J ;
DR   Q03053, POLG_CXB5P ;  Q9QL88, POLG_CXB6S ;  P27909, POLG_DEN1B ;
DR   P33478, POLG_DEN1S ;  P17763, POLG_DEN1W ;  P29990, POLG_DEN26 ;
DR   P29991, POLG_DEN27 ;  P14337, POLG_DEN28 ;  P07564, POLG_DEN2J ;
DR   P14340, POLG_DEN2N ;  P12823, POLG_DEN2P ;  Q9WDA6, POLG_DEN2Q ;
DR   P27914, POLG_DEN2T ;  Q99D35, POLG_DEN3C ;  Q5UB51, POLG_DEN3I ;
DR   Q6YMS3, POLG_DEN3M ;  P27915, POLG_DEN3P ;  Q6YMS4, POLG_DEN3S ;
DR   P09866, POLG_DEN4D ;  Q2YHF2, POLG_DEN4H ;  Q58HT7, POLG_DEN4P ;
DR   Q5UCB8, POLG_DEN4S ;  Q2YHF0, POLG_DEN4T ;  Q96725, POLG_EBHSG ;
DR   O91734, POLG_EC01F ;  Q9YLJ1, POLG_EC05N ;  Q66474, POLG_EC06C ;
DR   Q66577, POLG_EC09B ;  Q66849, POLG_EC09H ;  P29813, POLG_EC11G ;
DR   Q66575, POLG_EC12T ;  Q9WN78, POLG_EC30B ;  P03304, POLG_EMCV  ;
DR   P17593, POLG_EMCVB ;  P17594, POLG_EMCVD ;  P12296, POLG_ENMGO ;
DR   P27407, POLG_FCVC6 ;  P27408, POLG_FCVF4 ;  P27409, POLG_FCVF9 ;
DR   Q66914, POLG_FCVUR ;  P03306, POLG_FMDV1 ;  P03308, POLG_FMDVA ;
DR   P03305, POLG_FMDVO ;  P49303, POLG_FMDVZ ;  Q69422, POLG_GBVB  ;
DR   Q8V0N6, POLG_HAV88 ;  Q5Y944, POLG_HAVCF ;  Q67825, POLG_HAVGB ;
DR   A3FMB2, POLG_HAVH2 ;  Q05794, POLG_HAVHA ;  P08617, POLG_HAVHM ;
DR   A5LGW7, POLG_HAVJ8 ;  P06441, POLG_HAVLA ;  P13901, POLG_HAVMB ;
DR   Q9DWR1, POLG_HAVNO ;  P14553, POLG_HAVS2 ;  P26664, POLG_HCV1  ;
DR   Q5I2N3, POLG_HCV6A ;  Q68749, POLG_HCVBB ;  P26663, POLG_HCVBK ;
DR   Q9WMX2, POLG_HCVCO ;  O39929, POLG_HCVED ;  O39927, POLG_HCVEU ;
DR   O39928, POLG_HCVEV ;  P27958, POLG_HCVH  ;  Q81754, POLG_HCVH9 ;
DR   Q913D4, POLG_HCVIN ;  Q03463, POLG_HCVJ1 ;  O92972, POLG_HCVJ4 ;
DR   P26660, POLG_HCVJ6 ;  P26661, POLG_HCVJ8 ;  P26662, POLG_HCVJA ;
DR   Q99IB8, POLG_HCVJF ;  Q68801, POLG_HCVJK ;  Q68798, POLG_HCVJL ;
DR   Q9DHD6, POLG_HCVJP ;  Q00269, POLG_HCVJT ;  Q81495, POLG_HCVK3 ;
DR   Q81258, POLG_HCVNZ ;  Q913V3, POLG_HCVR6 ;  O91936, POLG_HCVSA ;
DR   O92529, POLG_HCVT5 ;  Q81487, POLG_HCVTR ;  P29846, POLG_HCVTW ;
DR   Q9QAX1, POLG_HCVVA ;  O92530, POLG_HCVVN ;  O92531, POLG_HCVVO ;
DR   O92532, POLG_HCVVP ;  P32537, POLG_HE701 ;  Q66478, POLG_HE71B ;
DR   Q66479, POLG_HE71M ;  Q66578, POLG_HPE1H ;  Q9YID8, POLG_HPE23 ;
DR   O73556, POLG_HPE2W ;  P03303, POLG_HRV14 ;  Q82122, POLG_HRV16 ;
DR   P12916, POLG_HRV1B ;  P04936, POLG_HRV2  ;  P07210, POLG_HRV8A ;
DR   P27395, POLG_JAEV1 ;  P19110, POLG_JAEV5 ;  P32886, POLG_JAEVJ ;
DR   P14403, POLG_JAEVN ;  P14335, POLG_KUNJM ;  P29837, POLG_LANVT ;
DR   P22338, POLG_LIV   ;  P54634, POLG_LORDV ;  P33515, POLG_MCFA  ;
DR   P05769, POLG_MVEV5 ;  Q83883, POLG_NVN68 ;  Q9QEJ5, POLG_PESV  ;
DR   O41174, POLG_PEV9U ;  P03300, POLG_POL1M ;  P03301, POLG_POL1S ;
DR   P06210, POLG_POL2L ;  P23069, POLG_POL2W ;  P06209, POLG_POL32 ;
DR   P03302, POLG_POL3L ;  Q04538, POLG_POWVL ;  P27411, POLG_RHDV3 ;
DR   Q86119, POLG_RHDVA ;  Q89273, POLG_RHDVB ;  P27410, POLG_RHDVF ;
DR   Q86117, POLG_RHDVS ;  P36286, POLG_SMSV1 ;  P36287, POLG_SMSV4 ;
DR   Q04544, POLG_SOUV3 ;  P09732, POLG_STEVM ;  P16604, POLG_SVDVH ;
DR   P13900, POLG_SVDVU ;  Q6XDK8, POLG_SVM10 ;  Q69014, POLG_SVM93 ;
DR   Q672I1, POLG_SVSAP ;  Q01299, POLG_TBEVH ;  P07720, POLG_TBEVS ;
DR   P14336, POLG_TBEVW ;  P08544, POLG_TMEVB ;  P13899, POLG_TMEVD ;
DR   P08545, POLG_TMEVG ;  Q9DUN3, POLG_VESVA ;  P06935, POLG_WNV   ;
DR   P03314, POLG_YEFV1 ;  Q6DV88, POLG_YEFVA ;  Q6J3P1, POLG_YEFVC ;
DR   Q074N0, POLG_YEFVE ;  Q89277, POLG_YEFVF ;  Q98803, POLG_YEFVI ;
DR   Q1X881, POLG_YEFVN ;  Q9YRV3, POLG_YEFVT ;  Q1X880, POLG_YEFVU ;
DR   Q86924, POLN_AURAV ;  P87515, POLN_BFV   ;  Q5XXP4, POLN_CHIK3 ;
DR   Q8JUX6, POLN_CHIKS ;  Q306W6, POLN_EEEV1 ;  Q306W8, POLN_EEEV8 ;
DR   Q4QXJ8, POLN_EEEVF ;  P36327, POLN_EEVV3 ;  Q8V294, POLN_EEVVC ;
DR   Q9WJC7, POLN_EEVVM ;  P36328, POLN_EEVVP ;  P27282, POLN_EEVVT ;
DR   Q5Y389, POLN_GETV  ;  Q8QZ73, POLN_MAYAB ;  P13886, POLN_ONNVG ;
DR   O90370, POLN_ONNVI ;  O90368, POLN_ONNVS ;  P13887, POLN_RRVN  ;
DR   Q6X2U4, POLN_RUBVB ;  Q6X2U2, POLN_RUBVC ;  Q9J6K9, POLN_RUBVD ;
DR   Q86500, POLN_RUBVM ;  Q8BCR0, POLN_RUBVN ;  Q99IE7, POLN_RUBVO ;
DR   O40955, POLN_RUBVR ;  P13889, POLN_RUBVT ;  Q99IE5, POLN_RUBVV ;
DR   Q9JGL0, POLN_SAGV  ;  P08411, POLN_SFV   ;  P27283, POLN_SINDO ;
DR   P03317, POLN_SINDV ;  Q8QL53, POLN_SLDV  ;  Q8JJX1, POLN_SPDV  ;
DR   P13896, POLN_WEEV  ;
//
ID   3.6.1.16
DE   CDP-glycerol diphosphatase.
AN   CDP-glycerol pyrophosphatase.
CA   CDP-glycerol + H(2)O = CMP + sn-glycerol 3-phosphate.
DR   A7YY53, ADPRM_BOVIN;  Q7T291, ADPRM_DANRE;  Q3LIE5, ADPRM_HUMAN;
DR   Q99KS6, ADPRM_MOUSE;  Q5M886, ADPRM_RAT  ;  Q7T0Q0, ADPRM_XENLA;
DR   Q66JJ3, ADPRM_XENTR;
//
ID   3.6.1.17
DE   Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical).
AN   Ap(4)A hydrolase.
AN   Ap(4)Aase.
AN   Ap4A hydrolase.
AN   Ap4Aase.
AN   Bis(5'-adenosyl)-tetraphosphatase.
AN   Bis(5'-guanosyl)-tetraphosphatase.
AN   Diadenosine 5',5'''-P(1),P(4)-tetraphosphate asymmetrical hydrolase.
AN   Diadenosinetetraphosphatase (asymmetrical).
AN   Diguanosinetetraphosphatase (asymmetrical).
AN   Dinucleosidetetraphosphatase (asymmetrical).
CA   P(1),P(4)-bis(5'-guanosyl) tetraphosphate + H(2)O = GTP + GMP.
CC   -!- Also acts on bis(5'-xanthosyl)-tetraphosphate and, more slowly,
CC       on bis(5'-adenosyl)-tetraphosphate and bis(5'-uridyl)-tetraphosphate
CC       (cf. EC 3.6.1.41).
PR   PROSITE; PDOC00694;
PR   PROSITE; PDOC00695;
DR   Q29RJ1, AP4A_BOVIN ;  P50583, AP4A_HUMAN ;  P56380, AP4A_MOUSE ;
DR   P50584, AP4A_PIG   ;  Q6PEC0, AP4A_RAT   ;  P49776, APH1_SCHPO ;
DR   Q9C6Z2, NUD25_ARATH;  Q9CAF2, NUD26_ARATH;  B7GLK2, PRPE_ANOFW ;
DR   A7Z3F2, PRPE_BACA2 ;  C3P3Q5, PRPE_BACAA ;  C3LBR5, PRPE_BACAC ;
DR   A0RB32, PRPE_BACAH ;  Q81TQ0, PRPE_BACAN ;  B7JEP5, PRPE_BACC0 ;
DR   Q73BU4, PRPE_BACC1 ;  B7ILE8, PRPE_BACC2 ;  C1ELB5, PRPE_BACC3 ;
DR   B7HGW3, PRPE_BACC4 ;  B7I0B6, PRPE_BACC7 ;  A7GM94, PRPE_BACCN ;
DR   B9IU03, PRPE_BACCQ ;  Q81GJ7, PRPE_BACCR ;  Q63EG2, PRPE_BACCZ ;
DR   Q9K907, PRPE_BACHD ;  Q6HLX9, PRPE_BACHK ;  Q65LA0, PRPE_BACLD ;
DR   O31614, PRPE_BACSU ;  A9VJS5, PRPE_BACWK ;  Q5L1R3, PRPE_GEOKA ;
DR   C5D7A6, PRPE_GEOSW ;  A4IL88, PRPE_GEOTN ;  Q8ERS7, PRPE_OCEIH ;
//
ID   3.6.1.18
DE   FAD diphosphatase.
AN   FAD pyrophosphatase.
CA   FAD + H(2)O = AMP + FMN.
CC   -!- The plant enzyme also hydrolyzes NAD(+) and NADH; the animal enzyme
CC       hydrolyzes NAD(+) and CoA at about half of the rate of hydrolysis of
CC       FAD.
CC   -!- May be identical with EC 3.6.1.9.
DR   P93740, NUD23_ARATH;
//
ID   3.6.1.19
DE   Nucleoside-triphosphate diphosphatase.
AN   Nucleoside-triphosphate pyrophosphatase.
CA   A nucleoside triphosphate + H(2)O = a nucleotide + diphosphate.
CC   -!- May be identical with EC 3.6.1.9.
DR   Q2KIC5, ITPA_BOVIN ;  Q54LQ6, ITPA_DICDI ;  Q9BY32, ITPA_HUMAN ;
DR   Q9D892, ITPA_MOUSE ;  A9NGK2, NTPA_ACHLI ;  A1TT41, NTPA_ACIAC ;
DR   Q6FEQ6, NTPA_ACIAD ;  B7H0A1, NTPA_ACIB3 ;  B7I4X1, NTPA_ACIB5 ;
DR   B2I3B3, NTPA_ACIBC ;  A3M1X9, NTPA_ACIBT ;  C1F8I0, NTPA_ACIC5 ;
DR   B9MEJ9, NTPA_ACIET ;  A1W4I7, NTPA_ACISJ ;  Q8UIG9, NTPA_AGRT5 ;
DR   Q2IEX2, NTPA_ANADE ;  A7HFW2, NTPA_ANADF ;  O66580, NTPA_AQUAE ;
DR   A8ESC9, NTPA_ARCB4 ;  Q5P5J5, NTPA_AROAE ;  Q81LB0, NTPA_BACAN ;
DR   Q72ZT2, NTPA_BACC1 ;  Q817P4, NTPA_BACCR ;  Q633V5, NTPA_BACCZ ;
DR   Q64MG2, NTPA_BACFR ;  Q9K8D9, NTPA_BACHD ;  Q6HD43, NTPA_BACHK ;
DR   Q65GG3, NTPA_BACLD ;  Q5WEM4, NTPA_BACSK ;  P94558, NTPA_BACSU ;
DR   Q8A327, NTPA_BACTN ;  Q6G565, NTPA_BARHE ;  Q6G1E6, NTPA_BARQU ;
DR   Q6MJR8, NTPA_BDEBA ;  B8DVS6, NTPA_BIFA0 ;  B3DTK7, NTPA_BIFLD ;
DR   Q8G7I1, NTPA_BIFLO ;  B7GN27, NTPA_BIFLS ;  Q0SNR4, NTPA_BORAP ;
DR   Q7WI95, NTPA_BORBR ;  O51263, NTPA_BORBU ;  B7J1H5, NTPA_BORBZ ;
DR   B5RL72, NTPA_BORDL ;  Q662B8, NTPA_BORGA ;  Q7W6C6, NTPA_BORPA ;
DR   Q7VXX8, NTPA_BORPE ;  B5RR63, NTPA_BORRA ;  Q89WK5, NTPA_BRAJA ;
DR   A5E8I8, NTPA_BRASB ;  P64305, NTPA_BRUME ;  P64306, NTPA_BRUSU ;
DR   Q62HZ7, NTPA_BURMA ;  Q63RV4, NTPA_BURPS ;  A7ZBP3, NTPA_CAMC1 ;
DR   A0RMP5, NTPA_CAMFF ;  A7HZE0, NTPA_CAMHC ;  A8FN54, NTPA_CAMJ8 ;
DR   A7H1W5, NTPA_CAMJD ;  Q9PMS6, NTPA_CAMJE ;  A1W0Z2, NTPA_CAMJJ ;
DR   Q5HT36, NTPA_CAMJR ;  Q9ABS4, NTPA_CAUCR ;  Q5L4Q6, NTPA_CHLAB ;
DR   Q821F9, NTPA_CHLCV ;  Q256I5, NTPA_CHLFF ;  Q9PJD4, NTPA_CHLMU ;
DR   Q9Z7D1, NTPA_CHLPN ;  B0B8I0, NTPA_CHLT2 ;  Q3KL90, NTPA_CHLTA ;
DR   B0BA59, NTPA_CHLTB ;  Q8KFJ6, NTPA_CHLTE ;  O84611, NTPA_CHLTR ;
DR   Q7NZJ6, NTPA_CHRVO ;  Q97FR2, NTPA_CLOAB ;  Q8XI68, NTPA_CLOPE ;
DR   Q891I4, NTPA_CLOTE ;  Q6NFN7, NTPA_CORDI ;  Q8FMU9, NTPA_COREF ;
DR   A4QGQ5, NTPA_CORGB ;  Q8NMR5, NTPA_CORGL ;  Q4JX01, NTPA_CORJK ;
DR   B1VGW8, NTPA_CORU7 ;  Q83FA3, NTPA_COXBU ;  C1CXX6, NTPA_DEIDV ;
DR   Q1IW81, NTPA_DEIGD ;  Q9RXX6, NTPA_DEIRA ;  A9BTA7, NTPA_DELAS ;
DR   Q6AQD7, NTPA_DESPS ;  A4J7Y6, NTPA_DESRM ;  Q726F4, NTPA_DESVH ;
DR   B5YEU3, NTPA_DICT6 ;  B2KEA9, NTPA_ELUMP ;  Q6D117, NTPA_ERWCT ;
DR   B2VEZ3, NTPA_ERWT9 ;  B1YJW5, NTPA_EXIS2 ;  C4L4I7, NTPA_EXISA ;
DR   A5FH89, NTPA_FLAJ1 ;  A6H0L2, NTPA_FLAPJ ;  Q0RQL6, NTPA_FRAAA ;
DR   Q5NEQ9, NTPA_FRATT ;  Q5KWI6, NTPA_GEOKA ;  Q74C80, NTPA_GEOSL ;
DR   Q7NN81, NTPA_GLOVI ;  Q5FRF4, NTPA_GLUOX ;  A0M0C9, NTPA_GRAFK ;
DR   Q7VLS3, NTPA_HAEDU ;  P44598, NTPA_HAEIN ;  A1WVN6, NTPA_HALHL ;
DR   Q7VF43, NTPA_HELHP ;  B4U8R9, NTPA_HYDS0 ;  A2BJY7, NTPA_HYPBU ;
DR   Q5QY51, NTPA_IDILO ;  A8A8W1, NTPA_IGNH4 ;  B1L6T7, NTPA_KORCO ;
DR   Q5FLV7, NTPA_LACAC ;  Q74KU4, NTPA_LACJO ;  Q9CG29, NTPA_LACLA ;
DR   Q88V20, NTPA_LACPL ;  Q5X245, NTPA_LEGPA ;  Q5ZSN3, NTPA_LEGPH ;
DR   Q5WTW9, NTPA_LEGPL ;  Q6AEL0, NTPA_LEIXX ;  B0SE38, NTPA_LEPBA ;
DR   B1Y0J8, NTPA_LEPCP ;  Q72UV8, NTPA_LEPIC ;  Q8F031, NTPA_LEPIN ;
DR   Q03YJ8, NTPA_LEUMM ;  Q92CH0, NTPA_LISIN ;  Q720J0, NTPA_LISMF ;
DR   Q8Y7N5, NTPA_LISMO ;  Q65RQ6, NTPA_MANSM ;  Q8TJS1, NTPA_METAC ;
DR   Q602P0, NTPA_METCA ;  B3DV19, NTPA_METI4 ;  Q57679, NTPA_METJA ;
DR   Q8TV07, NTPA_METKA ;  Q8PZ91, NTPA_METMA ;  A2SJB9, NTPA_METPP ;
DR   D9PYS9, NTPA_METTM ;  B1MLZ4, NTPA_MYCA9 ;  P64308, NTPA_MYCBO ;
DR   P52063, NTPA_MYCLE ;  Q6MT00, NTPA_MYCMS ;  Q73X89, NTPA_MYCPA ;
DR   Q8EVN6, NTPA_MYCPE ;  P64307, NTPA_MYCTU ;  B2A6I7, NTPA_NATTJ ;
DR   B9L638, NTPA_NAUPA ;  Q9JVG5, NTPA_NEIMA ;  Q9K0G6, NTPA_NEIMB ;
DR   Q82XJ3, NTPA_NITEU ;  A6Q5H7, NTPA_NITSB ;  Q5Z0V0, NTPA_NOCFA ;
DR   Q8YM52, NTPA_NOSS1 ;  Q8EPJ6, NTPA_OCEIH ;  B1ZXD5, NTPA_OPITP ;
DR   A6LGA4, NTPA_PARD8 ;  Q6MF40, NTPA_PARUW ;  Q9CKF5, NTPA_PASMU ;
DR   Q3A2Y7, NTPA_PELCD ;  Q7N7H2, NTPA_PHOLL ;  Q6LML4, NTPA_PHOPR ;
DR   Q6L1H9, NTPA_PICTO ;  A1VKF6, NTPA_POLNA ;  Q7MUC6, NTPA_PORGI ;
DR   Q6A760, NTPA_PROAC ;  A2C0B3, NTPA_PROM1 ;  Q7VDQ7, NTPA_PROMA ;
DR   Q7V4S3, NTPA_PROMM ;  Q7V316, NTPA_PROMP ;  Q46H95, NTPA_PROMT ;
DR   Q9I6A8, NTPA_PSEAE ;  Q88CT0, NTPA_PSEPK ;  Q87V88, NTPA_PSESM ;
DR   Q8ZVB5, NTPA_PYRAE ;  Q8U446, NTPA_PYRFU ;  O59580, NTPA_PYRHO ;
DR   Q5JEX8, NTPA_PYRKO ;  Q8XXF4, NTPA_RALSO ;  Q98DN4, NTPA_RHILO ;
DR   Q92SK4, NTPA_RHIME ;  Q7UGM3, NTPA_RHOBA ;  B6IVK5, NTPA_RHOCS ;
DR   Q21XZ3, NTPA_RHOFD ;  Q6NCY9, NTPA_RHOPA ;  Q2RN61, NTPA_RHORT ;
DR   Q8EBY7, NTPA_SHEON ;  Q5LWF7, NTPA_SILPO ;  Q5HGT2, NTPA_STAAC ;
DR   P64309, NTPA_STAAM ;  P99094, NTPA_STAAN ;  Q6GHT4, NTPA_STAAR ;
DR   Q6GA63, NTPA_STAAS ;  P58995, NTPA_STAAW ;  Q5HQ23, NTPA_STAEQ ;
DR   Q8CSY5, NTPA_STAES ;  Q8E3V8, NTPA_STRA3 ;  Q8DY93, NTPA_STRA5 ;
DR   Q82D15, NTPA_STRAW ;  Q9S2H9, NTPA_STRCO ;  Q8DSQ6, NTPA_STRMU ;
DR   Q9A1B6, NTPA_STRP1 ;  P0DB58, NTPA_STRP3 ;  Q5XDP8, NTPA_STRP6 ;
DR   Q8P2D2, NTPA_STRP8 ;  P64310, NTPA_STRPN ;  P0DB59, NTPA_STRPQ ;
DR   P64311, NTPA_STRR6 ;  Q5M1I4, NTPA_STRT1 ;  Q5M626, NTPA_STRT2 ;
DR   Q30UH9, NTPA_SULDN ;  A6Q6L9, NTPA_SULNB ;  Q97ZZ0, NTPA_SULSO ;
DR   B2V8P5, NTPA_SULSY ;  Q67SL4, NTPA_SYMTH ;  A0LG38, NTPA_SYNFM ;
DR   Q7U9M0, NTPA_SYNPX ;  Q0IDG4, NTPA_SYNS3 ;  P74432, NTPA_SYNY3 ;
DR   Q9HLA4, NTPA_THEAC ;  Q8DHZ6, NTPA_THEEB ;  Q9WY06, NTPA_THEMA ;
DR   A5IKR2, NTPA_THEP1 ;  B0KBM4, NTPA_THEP3 ;  B0K3T5, NTPA_THEPX ;
DR   Q72I42, NTPA_THET2 ;  Q5SHS6, NTPA_THET8 ;  Q8RC29, NTPA_THETN ;
DR   B5YHP2, NTPA_THEYD ;  B8GPB3, NTPA_THISH ;  Q73KE7, NTPA_TREDE ;
DR   O83452, NTPA_TREPA ;  B2S334, NTPA_TREPS ;  Q83HF7, NTPA_TROW8 ;
DR   Q83FT2, NTPA_TROWT ;  A1WQF4, NTPA_VEREI ;  Q9KUQ9, NTPA_VIBCH ;
DR   Q87LJ1, NTPA_VIBPA ;  Q8DCB9, NTPA_VIBVU ;  Q7MHJ0, NTPA_VIBVY ;
DR   Q8D3C3, NTPA_WIGBR ;  Q7MR19, NTPA_WOLSU ;  Q8PH61, NTPA_XANAC ;
DR   Q4UY37, NTPA_XANC8 ;  Q8P5T3, NTPA_XANCP ;  Q5H3S6, NTPA_XANOR ;
DR   Q9PD73, NTPA_XYLFA ;  Q87DG2, NTPA_XYLFT ;  Q8ZHF4, NTPA_YERPE ;
DR   Q666N1, NTPA_YERPS ;  Q5NRL7, NTPA_ZYMMO ;  Q8XCU5, RDGB_ECO57 ;
DR   Q8FE27, RDGB_ECOL6 ;  P52061, RDGB_ECOLI ;  Q5PMK9, RDGB_SALPA ;
DR   Q8Z3U6, RDGB_SALTI ;  Q8ZM45, RDGB_SALTY ;  Q83JS0, RDGB_SHIFL ;
//
ID   3.6.1.20
DE   5'-acylphosphoadenosine hydrolase.
CA   5'-acylphosphoadenosine + H(2)O = AMP + a carboxylate.
CC   -!- Also acts on inosine and uridine compounds.
//
ID   3.6.1.21
DE   ADP-sugar diphosphatase.
AN   ADP-sugar pyrophosphatase.
CA   ADP-sugar + H(2)O = AMP + alpha-D-aldose 1-phosphate.
CC   -!- Has a distinct specificity from EC 3.6.1.45.
DR   Q9SZ63, NUD14_ARATH;
//
ID   3.6.1.22
DE   NAD(+) diphosphatase.
AN   NAD(+) pyrophosphatase.
AN   NAD+ pyrophosphatase.
AN   NADH pyrophosphatase.
AN   NADP pyrophosphatase.
CA   NAD(+) + H(2)O = AMP + NMN.
CC   -!- Also acts on NADP(+), 3-acetylpyridine and the thionicotinamide
CC       analogs of NAD(+) and NADP(+).
PR   PROSITE; PDOC00695;
DR   Q19427, NPY1_CAEEL ;  Q9Y7J0, NPY1_SCHPO ;  P53164, NPY1_YEAST ;
DR   Q6NPD7, NUD10_ARATH;  Q29RH3, NUD12_BOVIN;  Q9BQG2, NUD12_HUMAN;
DR   Q4R7L8, NUD12_MACFA;  Q9DCN1, NUD12_MOUSE;  Q5RD76, NUD12_PONAB;
DR   Q94A82, NUD19_ARATH;  A6VQT1, NUDC_ACTSZ ;  Q7NTZ8, NUDC_CHRVO ;
DR   A8AKS7, NUDC_CITK8 ;  Q9RV62, NUDC_DEIRA ;  A7ZUL1, NUDC_ECO24 ;
DR   B7UPF1, NUDC_ECO27 ;  B7MIY2, NUDC_ECO45 ;  B7LA85, NUDC_ECO55 ;
DR   Q8X6X7, NUDC_ECO57 ;  B5Z092, NUDC_ECO5E ;  B7NRS9, NUDC_ECO7I ;
DR   B7N2J8, NUDC_ECO81 ;  B7M7Q5, NUDC_ECO8A ;  C5A0T7, NUDC_ECOBW ;
DR   B1XBZ9, NUDC_ECODH ;  A8A796, NUDC_ECOHS ;  A1AIG7, NUDC_ECOK1 ;
DR   Q0TA69, NUDC_ECOL5 ;  Q8FB75, NUDC_ECOL6 ;  B1IUQ1, NUDC_ECOLC ;
DR   P32664, NUDC_ECOLI ;  B7NFT7, NUDC_ECOLU ;  B6I5K7, NUDC_ECOSE ;
DR   B1LNU8, NUDC_ECOSM ;  Q1R5W2, NUDC_ECOUT ;  C5BHE7, NUDC_EDWI9 ;
DR   A4W5B9, NUDC_ENT38 ;  A7MJ81, NUDC_ENTS8 ;  Q6DAL8, NUDC_ERWCT ;
DR   B2VG76, NUDC_ERWT9 ;  B7LUK6, NUDC_ESCF3 ;  Q4QNB3, NUDC_HAEI8 ;
DR   A5UA57, NUDC_HAEIE ;  A5UGU3, NUDC_HAEIG ;  P44710, NUDC_HAEIN ;
DR   B5XYE2, NUDC_KLEP3 ;  A6TGQ3, NUDC_KLEP7 ;  Q65W71, NUDC_MANSM ;
DR   Q7TX14, NUDC_MYCBO ;  A1KNJ7, NUDC_MYCBP ;  C1AGW8, NUDC_MYCBT ;
DR   A5U7L9, NUDC_MYCTA ;  O53345, NUDC_MYCTU ;  P57965, NUDC_PASMU ;
DR   C6DHS8, NUDC_PECCP ;  Q7N961, NUDC_PHOLL ;  Q6LLW5, NUDC_PHOPR ;
DR   Q48IH8, NUDC_PSE14 ;  A6V6Z8, NUDC_PSEA7 ;  B7VB54, NUDC_PSEA8 ;
DR   Q02KW6, NUDC_PSEAB ;  O86062, NUDC_PSEAE ;  Q1IBF8, NUDC_PSEE4 ;
DR   Q4KBL2, NUDC_PSEF5 ;  A5W1F2, NUDC_PSEP1 ;  Q3KC83, NUDC_PSEPF ;
DR   B0KMR5, NUDC_PSEPG ;  Q88FQ8, NUDC_PSEPK ;  B1J6H6, NUDC_PSEPW ;
DR   Q882A9, NUDC_PSESM ;  Q4ZTN0, NUDC_PSEU2 ;  A4VLQ5, NUDC_PSEU5 ;
DR   B5F1H9, NUDC_SALA4 ;  Q57H59, NUDC_SALCH ;  B5FQL1, NUDC_SALDC ;
DR   B5QYF1, NUDC_SALEP ;  B5RFI8, NUDC_SALG2 ;  B4TCT5, NUDC_SALHS ;
DR   B4T0Z8, NUDC_SALNS ;  Q5PKA4, NUDC_SALPA ;  A9N0K8, NUDC_SALPB ;
DR   C0Q2S8, NUDC_SALPC ;  B5BJR5, NUDC_SALPK ;  B4TQK6, NUDC_SALSV ;
DR   Q8Z328, NUDC_SALTI ;  Q9L9I5, NUDC_SALTY ;  B2TWI3, NUDC_SHIB3 ;
DR   Q31U01, NUDC_SHIBS ;  Q32AG9, NUDC_SHIDS ;  Q0SY04, NUDC_SHIF8 ;
DR   Q83IS3, NUDC_SHIFL ;  Q3YUY8, NUDC_SHISS ;  A5F3M9, NUDC_VIBC3 ;
DR   Q9KV27, NUDC_VIBCH ;  C3LR63, NUDC_VIBCM ;  Q87KQ7, NUDC_VIBPA ;
DR   B7VM66, NUDC_VIBSL ;  Q8DD17, NUDC_VIBVU ;  A1JIJ0, NUDC_YERE8 ;
DR   A7FNH4, NUDC_YERP3 ;  Q1C1V1, NUDC_YERPA ;  B2K122, NUDC_YERPB ;
DR   Q8ZAQ5, NUDC_YERPE ;  A9R8D3, NUDC_YERPG ;  Q1CN68, NUDC_YERPN ;
DR   A4TS22, NUDC_YERPP ;  Q66FP3, NUDC_YERPS ;  B1JJK8, NUDC_YERPY ;
DR   Q9CA40, NUDT1_ARATH;  Q94B74, NUDT2_ARATH;  Q9LE73, NUDT4_ARATH;
DR   Q9SJC4, NUDT6_ARATH;  Q9SU14, NUDT7_ARATH;
//
ID   3.6.1.23
DE   dUTP diphosphatase.
AN   Deoxyuridine-triphosphatase.
AN   Desoxyuridine 5'-triphosphatase.
AN   Desoxyuridine 5'-triphosphate nucleotidohydrolase.
AN   dUTP pyrophosphatase.
AN   dUTPase.
CA   dUTP + H(2)O = dUMP + diphosphate.
DR   Q91F87, 438L_IIV6  ;  Q65199, DUTP_ASFB7 ;  P0C9C5, DUTP_ASFK5 ;
DR   Q65243, DUTP_ASFM2 ;  P0C9C3, DUTP_ASFP4 ;  P0C9C4, DUTP_ASFWA ;
DR   B0C9N7, DUT_ACAM1  ;  Q6FDR0, DUT_ACIAD  ;  B7GYK9, DUT_ACIB3  ;
DR   B7I7U2, DUT_ACIB5  ;  B2HV28, DUT_ACIBC  ;  B0VTE5, DUT_ACIBS  ;
DR   A3M324, DUT_ACIBT  ;  B0V8Y8, DUT_ACIBY  ;  A5FZ98, DUT_ACICJ  ;
DR   A3N3Q6, DUT_ACTP2  ;  B3H338, DUT_ACTP7  ;  B0BTZ3, DUT_ACTPJ  ;
DR   A6VK96, DUT_ACTSZ  ;  Q89662, DUT_ADEG1  ;  Q9YYS0, DUT_ADEG8  ;
DR   A0KEM6, DUT_AERHH  ;  Q9YG32, DUT_AERPE  ;  A4STD7, DUT_AERS4  ;
DR   B9J7P6, DUT_AGRRK  ;  Q8UII1, DUT_AGRT5  ;  Q0VT60, DUT_ALCBS  ;
DR   O36404, DUT_ALHV1  ;  A6TLM6, DUT_ALKMQ  ;  B8JFZ2, DUT_ANAD2  ;
DR   Q2IQ00, DUT_ANADE  ;  A7H9F9, DUT_ANADF  ;  B9KIY0, DUT_ANAMF  ;
DR   Q5PAE6, DUT_ANAMM  ;  B4UHG6, DUT_ANASK  ;  Q6E4Q0, DUT_ANTLO  ;
DR   O66592, DUT_AQUAE  ;  Q9STG6, DUT_ARATH  ;  O29157, DUT_ARCFU  ;
DR   Q5P7Z9, DUT_AROAE  ;  Q74ZF0, DUT_ASHGO  ;  A8IPW5, DUT_AZOC5  ;
DR   A1K4K1, DUT_AZOSB  ;  C1DI55, DUT_AZOVD  ;  Q5LIH9, DUT_BACFN  ;
DR   Q64ZK3, DUT_BACFR  ;  Q8A245, DUT_BACTN  ;  A6L083, DUT_BACV8  ;
DR   A1URB3, DUT_BARBK  ;  Q6G202, DUT_BARHE  ;  Q6FYR2, DUT_BARQU  ;
DR   Q1LTS1, DUT_BAUCH  ;  P61906, DUT_BDEBA  ;  B2IKJ9, DUT_BEII9  ;
DR   B3DRA9, DUT_BIFLD  ;  Q8G4E8, DUT_BIFLO  ;  B7GQI9, DUT_BIFLS  ;
DR   Q7VRK0, DUT_BLOFL  ;  Q491W8, DUT_BLOPB  ;  Q2L2L5, DUT_BORA1  ;
DR   Q7WKE3, DUT_BORBR  ;  Q7W8Z8, DUT_BORPA  ;  Q7VVR1, DUT_BORPE  ;
DR   O48500, DUT_BPT5   ;  O52597, DUT_BRAJA  ;  A5E891, DUT_BRASB  ;
DR   A4YJH3, DUT_BRASO  ;  B2S7B5, DUT_BRUA1  ;  Q2YRG4, DUT_BRUA2  ;
DR   Q57BK5, DUT_BRUAB  ;  A9M7H5, DUT_BRUC2  ;  C0REU2, DUT_BRUMB  ;
DR   P64004, DUT_BRUME  ;  A9WWF2, DUT_BRUSI  ;  P64005, DUT_BRUSU  ;
DR   B8D8C4, DUT_BUCA5  ;  P57623, DUT_BUCAI  ;  Q8K921, DUT_BUCAP  ;
DR   B8D881, DUT_BUCAT  ;  P59408, DUT_BUCBP  ;  B1YVA7, DUT_BURA4  ;
DR   Q1BU98, DUT_BURCA  ;  B1JXC6, DUT_BURCC  ;  A0K9T8, DUT_BURCH  ;
DR   B4E900, DUT_BURCJ  ;  Q0BCK5, DUT_BURCM  ;  A9AGN3, DUT_BURM1  ;
DR   A3MN10, DUT_BURM7  ;  A2S504, DUT_BURM9  ;  Q62HL1, DUT_BURMA  ;
DR   A1V6V5, DUT_BURMS  ;  A3NSC8, DUT_BURP0  ;  Q3JV72, DUT_BURP1  ;
DR   A3N6P4, DUT_BURP6  ;  B2JDY5, DUT_BURP8  ;  B2T6J1, DUT_BURPP  ;
DR   Q63WI6, DUT_BURPS  ;  Q39DM5, DUT_BURS3  ;  Q2T0H6, DUT_BURTA  ;
DR   A4JH35, DUT_BURVG  ;  Q13UV8, DUT_BURXL  ;  Q8V2Y0, DUT_CAMPM  ;
DR   Q775Z7, DUT_CAMPS  ;  P43058, DUT_CANAL  ;  Q6FKQ6, DUT_CANGA  ;
DR   B8GVZ0, DUT_CAUCN  ;  Q9A253, DUT_CAUCR  ;  Q5L6D8, DUT_CHLAB  ;
DR   Q3AQ75, DUT_CHLCH  ;  Q823Q9, DUT_CHLCV  ;  Q253V7, DUT_CHLFF  ;
DR   B3EIP1, DUT_CHLL2  ;  Q9PKA2, DUT_CHLMU  ;  B3QML1, DUT_CHLP8  ;
DR   B3EPL0, DUT_CHLPB  ;  A1BEP9, DUT_CHLPD  ;  Q9Z9C2, DUT_CHLPN  ;
DR   B0B7K8, DUT_CHLT2  ;  B3QW69, DUT_CHLT3  ;  Q3KM70, DUT_CHLTA  ;
DR   B0BBS3, DUT_CHLTB  ;  O68992, DUT_CHLTE  ;  O84294, DUT_CHLTR  ;
DR   Q7MBE8, DUT_CHRVO  ;  A8ARM7, DUT_CITK8  ;  Q97J61, DUT_CLOAB  ;
DR   Q181Y7, DUT_CLOD6  ;  O30931, DUT_CLODI  ;  A5N7A5, DUT_CLOK5  ;
DR   A0Q1N5, DUT_CLONN  ;  Q895R1, DUT_CLOTE  ;  P61907, DUT_CORDI  ;
DR   Q8FPH9, DUT_COREF  ;  A4QER2, DUT_CORGB  ;  Q8NPA9, DUT_CORGL  ;
DR   Q4JVB1, DUT_CORJK  ;  A9KGS5, DUT_COXBN  ;  A9NB28, DUT_COXBR  ;
DR   Q45920, DUT_COXBU  ;  P87630, DUT_CWPXG  ;  B1WN93, DUT_CYAA5  ;
DR   B7KFZ3, DUT_CYAP7  ;  Q11Z53, DUT_CYTH3  ;  Q6BRN7, DUT_DEBHA  ;
DR   Q47BB1, DUT_DECAR  ;  B8FQZ6, DUT_DESHD  ;  Q24UJ8, DUT_DESHY  ;
DR   Q6AJZ0, DUT_DESPS  ;  Q54BW5, DUT_DICDI  ;  A5EYG1, DUT_DICNV  ;
DR   B5YDD8, DUT_DICT6  ;  B8E029, DUT_DICTD  ;  A8LKC5, DUT_DINSH  ;
DR   Q07275, DUT_EBVA8  ;  P03195, DUT_EBVB9  ;  Q3KST7, DUT_EBVG   ;
DR   A7ZTJ1, DUT_ECO24  ;  B7UM46, DUT_ECO27  ;  B7MFK1, DUT_ECO45  ;
DR   B7L763, DUT_ECO55  ;  P64007, DUT_ECO57  ;  B5YWD8, DUT_ECO5E  ;
DR   B7NQ01, DUT_ECO7I  ;  B7N1U1, DUT_ECO81  ;  B7M4C5, DUT_ECO8A  ;
DR   C4ZXN2, DUT_ECOBW  ;  B1X974, DUT_ECODH  ;  A8A6A2, DUT_ECOHS  ;
DR   A1AHH1, DUT_ECOK1  ;  Q0TBG9, DUT_ECOL5  ;  P64006, DUT_ECOL6  ;
DR   B1IYW0, DUT_ECOLC  ;  P06968, DUT_ECOLI  ;  B7NEU4, DUT_ECOLU  ;
DR   B6I3L7, DUT_ECOSE  ;  B1LK77, DUT_ECOSM  ;  Q1R4V2, DUT_ECOUT  ;
DR   Q3YRU2, DUT_EHRCJ  ;  P28892, DUT_EHV1B  ;  Q66656, DUT_EHV2   ;
DR   Q00030, DUT_EHV4   ;  Q8SRS0, DUT_ENCCU  ;  A4W509, DUT_ENT38  ;
DR   A7MQ93, DUT_ENTS8  ;  Q6DAV9, DUT_ERWCT  ;  B2VF80, DUT_ERWT9  ;
DR   B7LVK1, DUT_ESCF3  ;  B0S1D8, DUT_FINM2  ;  A5FL22, DUT_FLAJ1  ;
DR   Q9J5G5, DUT_FOWPN  ;  B0U0Z5, DUT_FRAP2  ;  Q14JC6, DUT_FRAT1  ;
DR   A7N9S0, DUT_FRATF  ;  Q2A5H6, DUT_FRATH  ;  B2SDZ1, DUT_FRATM  ;
DR   A0Q4H7, DUT_FRATN  ;  Q0BNT3, DUT_FRATO  ;  Q5NHX4, DUT_FRATT  ;
DR   A4IZU0, DUT_FRATW  ;  Q6GZR2, DUT_FRG3G  ;  Q8RER7, DUT_FUSNN  ;
DR   Q9E6M6, DUT_GAHVM  ;  B5EI65, DUT_GEOBB  ;  Q39V99, DUT_GEOMG  ;
DR   B9M1G7, DUT_GEOSF  ;  P61908, DUT_GEOSL  ;  C6E2P3, DUT_GEOSM  ;
DR   Q7NKL2, DUT_GLOVI  ;  Q5FN20, DUT_GLUOX  ;  Q7VN49, DUT_HAEDU  ;
DR   Q4QLV3, DUT_HAEI8  ;  A5UDB4, DUT_HAEIE  ;  A5UI95, DUT_HAEIG  ;
DR   P43792, DUT_HAEIN  ;  B8F854, DUT_HAEPS  ;  Q0I0Y1, DUT_HAES1  ;
DR   B0UUW5, DUT_HAES2  ;  Q2SN67, DUT_HAHCH  ;  A1WZE9, DUT_HALHL  ;
DR   B0R858, DUT_HALS3  ;  Q9HMF3, DUT_HALSA  ;  C4K8Y6, DUT_HAMD5  ;
DR   P16824, DUT_HCMVA  ;  Q17WJ4, DUT_HELAH  ;  Q7VJU0, DUT_HELHP  ;
DR   B0TAH2, DUT_HELMI  ;  B6JM89, DUT_HELP2  ;  Q1CT07, DUT_HELPH  ;
DR   Q9ZKY3, DUT_HELPJ  ;  B2USW5, DUT_HELPS  ;  O25536, DUT_HELPY  ;
DR   A4G3E3, DUT_HERAR  ;  P10234, DUT_HHV11  ;  P89469, DUT_HHV2H  ;
DR   P30007, DUT_HHV6G  ;  Q06095, DUT_HHV6U  ;  P52541, DUT_HHV6Z  ;
DR   P52341, DUT_HHV7J  ;  P33316, DUT_HUMAN  ;  B4U6R8, DUT_HYDS0  ;
DR   P28893, DUT_ICHVA  ;  Q5QZB6, DUT_IDILO  ;  A6SW68, DUT_JANMA  ;
DR   B5XTG3, DUT_KLEP3  ;  A6TFN1, DUT_KLEP7  ;  Q6CQN7, DUT_KLULA  ;
DR   Q9CJ30, DUT_LACLA  ;  C1D8V4, DUT_LARHH  ;  Q5X242, DUT_LEGPA  ;
DR   A5IEX1, DUT_LEGPC  ;  Q5ZSN0, DUT_LEGPH  ;  Q5WTW6, DUT_LEGPL  ;
DR   Q6AFE0, DUT_LEIXX  ;  Q04QV4, DUT_LEPBJ  ;  Q04Z61, DUT_LEPBL  ;
DR   B1Y839, DUT_LEPCP  ;  P61909, DUT_LEPIC  ;  Q8F729, DUT_LEPIN  ;
DR   Q65R66, DUT_MANSM  ;  Q0AK44, DUT_MARMM  ;  Q8TGX9, DUT_METAC  ;
DR   Q46EG2, DUT_METBF  ;  Q12XH1, DUT_METBU  ;  Q603M1, DUT_METCA  ;
DR   Q1H4K3, DUT_METFK  ;  Q58502, DUT_METJA  ;  Q8TV34, DUT_METKA  ;
DR   Q8PWG1, DUT_METMA  ;  A2SIY4, DUT_METPP  ;  B8ET39, DUT_METSB  ;
DR   O27642, DUT_METTH  ;  Q69151, DUT_MUHVS  ;  A0QIM8, DUT_MYCA1  ;
DR   P0A553, DUT_MYCBO  ;  A1KM35, DUT_MYCBP  ;  C1AFF6, DUT_MYCBT  ;
DR   A4TCR4, DUT_MYCGI  ;  B8ZQW4, DUT_MYCLB  ;  Q49992, DUT_MYCLE  ;
DR   B2HM03, DUT_MYCMM  ;  P61910, DUT_MYCPA  ;  A0QW08, DUT_MYCS2  ;
DR   A3PYI9, DUT_MYCSJ  ;  A1UF27, DUT_MYCSK  ;  A5U649, DUT_MYCTA  ;
DR   P0A552, DUT_MYCTU  ;  A0PT52, DUT_MYCUA  ;  A1T7Y0, DUT_MYCVP  ;
DR   B9L823, DUT_NAUPA  ;  Q5F9E0, DUT_NEIG1  ;  B4RKH1, DUT_NEIG2  ;
DR   A9M439, DUT_NEIM0  ;  Q9JUW1, DUT_NEIMA  ;  Q9JZU7, DUT_NEIMB  ;
DR   Q2GCH5, DUT_NEOSM  ;  Q6MVL2, DUT_NEUCR  ;  Q0AHX8, DUT_NITEC  ;
DR   Q82UM1, DUT_NITEU  ;  Q1QS44, DUT_NITHX  ;  Q2Y742, DUT_NITMU  ;
DR   Q3J6W1, DUT_NITOC  ;  Q3SWM9, DUT_NITWN  ;  Q5YT90, DUT_NOCFA  ;
DR   B6JCQ3, DUT_OLICO  ;  P14597, DUT_ORFN2  ;  A5CD09, DUT_ORITB  ;
DR   B3CSS7, DUT_ORITI  ;  Q10FF9, DUT_ORYSJ  ;  A7HZC0, DUT_PARL1  ;
DR   Q6MEK7, DUT_PARUW  ;  P57914, DUT_PASMU  ;  O41033, DUT_PBCV1  ;
DR   C6DIC3, DUT_PECCP  ;  Q3A499, DUT_PELCD  ;  Q3B304, DUT_PELLD  ;
DR   B4SBF1, DUT_PELPB  ;  Q7MAX3, DUT_PHOLL  ;  B1XW28, DUT_POLNS  ;
DR   A4SZP2, DUT_POLSQ  ;  B2RJH1, DUT_PORG3  ;  Q7MVT6, DUT_PORGI  ;
DR   Q9F7S4, DUT_PRB01  ;  B4S912, DUT_PROA2  ;  Q6A8W1, DUT_PROAC  ;
DR   B4F0W6, DUT_PROMH  ;  A4SFI9, DUT_PROVI  ;  Q48Q06, DUT_PSE14  ;
DR   A6VEC8, DUT_PSEA7  ;  B7V5L2, DUT_PSEA8  ;  Q02E41, DUT_PSEAB  ;
DR   Q9HTN3, DUT_PSEAE  ;  Q1I2U1, DUT_PSEE4  ;  Q4K3S2, DUT_PSEF5  ;
DR   C3K473, DUT_PSEFS  ;  A4Y0K9, DUT_PSEMY  ;  A5WB04, DUT_PSEP1  ;
DR   Q3K4M6, DUT_PSEPF  ;  B0KQ89, DUT_PSEPG  ;  Q88C95, DUT_PSEPK  ;
DR   B1J4L9, DUT_PSEPW  ;  Q88BD3, DUT_PSESM  ;  Q4ZZX9, DUT_PSEU2  ;
DR   A4VGS6, DUT_PSEU5  ;  Q6UDM0, DUT_PSHV1  ;  Q4FU67, DUT_PSYA2  ;
DR   Q1QDA0, DUT_PSYCK  ;  A1SR17, DUT_PSYIN  ;  A5WGH5, DUT_PSYWF  ;
DR   Q6RZR1, DUT_RABPU  ;  B2UAR0, DUT_RALPJ  ;  Q8XWL1, DUT_RALSO  ;
DR   P70583, DUT_RAT    ;  B3PZ69, DUT_RHIE6  ;  Q2KDD4, DUT_RHIEC  ;
DR   Q1MMG6, DUT_RHIL3  ;  Q98C10, DUT_RHILO  ;  B5ZYI7, DUT_RHILW  ;
DR   Q92SM6, DUT_RHIME  ;  B6IVT5, DUT_RHOCS  ;  C0ZYU5, DUT_RHOE4  ;
DR   Q21V41, DUT_RHOFD  ;  Q2J2H6, DUT_RHOP2  ;  P61911, DUT_RHOPA  ;
DR   Q21CD0, DUT_RHOPB  ;  Q13EP1, DUT_RHOPS  ;  B3Q616, DUT_RHOPT  ;
DR   Q3J0B2, DUT_RHOS4  ;  B9KL02, DUT_RHOSK  ;  C3PNB9, DUT_RICAE  ;
DR   A8GNB1, DUT_RICAH  ;  A8GXE5, DUT_RICB8  ;  Q1RJQ1, DUT_RICBR  ;
DR   A8EZ30, DUT_RICCK  ;  Q92I74, DUT_RICCN  ;  Q4ULV2, DUT_RICFE  ;
DR   A8F1H0, DUT_RICM5  ;  Q9ZDD2, DUT_RICPR  ;  C4K2C2, DUT_RICPU  ;
DR   B0BXE1, DUT_RICRO  ;  A8GRY1, DUT_RICRS  ;  Q68WX8, DUT_RICTY  ;
DR   Q16AZ3, DUT_ROSDO  ;  B5EXE4, DUT_SALA4  ;  A9MKN5, DUT_SALAR  ;
DR   Q57IA2, DUT_SALCH  ;  B5FM63, DUT_SALDC  ;  B5R5G4, DUT_SALEP  ;
DR   B5RGE7, DUT_SALG2  ;  B4T9C4, DUT_SALHS  ;  B4SXE1, DUT_SALNS  ;
DR   Q5PC28, DUT_SALPA  ;  A9MVN5, DUT_SALPB  ;  C0Q1X2, DUT_SALPC  ;
DR   B5BI14, DUT_SALPK  ;  B4TZY1, DUT_SALSV  ;  P64009, DUT_SALTI  ;
DR   P64008, DUT_SALTY  ;  Q9P6Q5, DUT_SCHPO  ;  A8GLE7, DUT_SERP5  ;
DR   A1S2D0, DUT_SHEAM  ;  B8E4J3, DUT_SHEB2  ;  A3CZJ4, DUT_SHEB5  ;
DR   A6WIA4, DUT_SHEB8  ;  A9KY02, DUT_SHEB9  ;  Q12SF7, DUT_SHEDO  ;
DR   Q07WF9, DUT_SHEFN  ;  B0TQK9, DUT_SHEHH  ;  A3QIQ1, DUT_SHELP  ;
DR   Q8E9M0, DUT_SHEON  ;  A8H9B2, DUT_SHEPA  ;  A4Y2K9, DUT_SHEPC  ;
DR   B8CM27, DUT_SHEPW  ;  A0L1S1, DUT_SHESA  ;  A8FQ73, DUT_SHESH  ;
DR   Q0HE54, DUT_SHESM  ;  Q0HZU5, DUT_SHESR  ;  A1REU2, DUT_SHESW  ;
DR   B1KL07, DUT_SHEWM  ;  B2TTV4, DUT_SHIB3  ;  Q31UY6, DUT_SHIBS  ;
DR   Q329L7, DUT_SHIDS  ;  Q0SYG7, DUT_SHIF8  ;  Q83PN3, DUT_SHIFL  ;
DR   Q3YW02, DUT_SHISS  ;  Q01034, DUT_SHV21  ;  Q5LWD3, DUT_SILPO  ;
DR   A6UFD9, DUT_SINMW  ;  O71028, DUT_SIRV1  ;  Q2NQU0, DUT_SODGM  ;
DR   P32518, DUT_SOLLC  ;  Q02BZ2, DUT_SOLUE  ;  A5VG00, DUT_SPHWW  ;
DR   Q82KK4, DUT_STRAW  ;  O54134, DUT_STRCO  ;  B1VXM7, DUT_STRGG  ;
DR   Q90030, DUT_SUHVK  ;  P32208, DUT_SWPVK  ;  Q2LWT5, DUT_SYNAS  ;
DR   B1XM22, DUT_SYNP2  ;  Q0AYH7, DUT_SYNWW  ;  Q47NK1, DUT_THEFY  ;
DR   B0K9P1, DUT_THEP3  ;  B0K1C7, DUT_THEPX  ;  Q8RA46, DUT_THETN  ;
DR   Q31EC7, DUT_THICR  ;  Q3SFR7, DUT_THIDA  ;  C4L816, DUT_TOLAT  ;
DR   P61912, DUT_TREDE  ;  O83855, DUT_TREPA  ;  B2S4C2, DUT_TREPS  ;
DR   Q113K0, DUT_TRIEI  ;  Q83I22, DUT_TROW8  ;  Q83G43, DUT_TROWT  ;
DR   Q76RE7, DUT_VACCA  ;  P68634, DUT_VACCC  ;  P68635, DUT_VACCP  ;
DR   P17374, DUT_VACCW  ;  P33826, DUT_VAR67  ;  P09254, DUT_VZVD   ;
DR   Q4JQW7, DUT_VZVO   ;  Q8D2F3, DUT_WIGBR  ;  P61913, DUT_WOLPM  ;
DR   B3CL69, DUT_WOLPP  ;  Q7M9N1, DUT_WOLSU  ;  Q5GST1, DUT_WOLTR  ;
DR   C0R5L9, DUT_WOLWR  ;  Q8PFR5, DUT_XANAC  ;  Q3BNA6, DUT_XANC5  ;
DR   Q4UPP2, DUT_XANC8  ;  B0RXM3, DUT_XANCB  ;  Q8P458, DUT_XANCP  ;
DR   Q2P8A8, DUT_XANOM  ;  B2SS19, DUT_XANOP  ;  Q5H5L9, DUT_XANOR  ;
DR   B2I6M7, DUT_XYLF2  ;  Q9PGZ6, DUT_XYLFA  ;  B0U1I2, DUT_XYLFM  ;
DR   Q87F19, DUT_XYLFT  ;  Q6C141, DUT_YARLI  ;  P33317, DUT_YEAST  ;
DR   A1JHX0, DUT_YERE8  ;  A7FCT2, DUT_YERP3  ;  Q8ZJP5, DUT_YERPE  ;
DR   A9R672, DUT_YERPG  ;  Q66GD8, DUT_YERPS  ;  Q6TUZ4, DUT_YMTV5  ;
DR   Q9X3X5, DUT_ZYMMO  ;  P89079, E4OR1_ADE09;  P16088, POL_FIVPE  ;
DR   P19028, POL_FIVSD  ;  P31822, POL_FIVT2  ;  P16901, POL_OMVVS  ;
DR   P03370, POL_VILV   ;  P23426, POL_VILV1  ;  P23427, POL_VILV2  ;
DR   P35956, POL_VILVK  ;  P31625, VPRT_JSRV  ;  O31801, YNCF_BACSU ;
DR   O34919, YOSS_BACSU ;
//
ID   3.6.1.24
DE   Nucleoside phosphoacylhydrolase.
CA   Hydrolyzes mixed phospho-anhydride bonds.
CC   -!- Attacks ribonucleoside 5'-nitrophenylphosphates, but is inactive
CC       against phosphodiesters.
//
ID   3.6.1.25
DE   Triphosphatase.
CA   Triphosphate + H(2)O = diphosphate + phosphate.
//
ID   3.6.1.26
DE   CDP-diacylglycerol diphosphatase.
AN   CDP-diacylglycerol phosphatidylhydrolase.
AN   CDP-diacylglycerol pyrophosphatase.
CA   CDP-diacylglycerol + H(2)O = CMP + phosphatidate.
DR   A8AL09, CDH_CITK8  ;  A7ZUD2, CDH_ECO24  ;  B7UNN8, CDH_ECO27  ;
DR   B7MI50, CDH_ECO45  ;  B7LA15, CDH_ECO55  ;  Q8X7A5, CDH_ECO57  ;
DR   B5YZ56, CDH_ECO5E  ;  B7NU89, CDH_ECO7I  ;  B7N2Q9, CDH_ECO81  ;
DR   B7M6W9, CDH_ECO8A  ;  C5A085, CDH_ECOBW  ;  B1XB84, CDH_ECODH  ;
DR   A8A723, CDH_ECOHS  ;  Q8FBC8, CDH_ECOL6  ;  B1IVG1, CDH_ECOLC  ;
DR   P06282, CDH_ECOLI  ;  B7NFL5, CDH_ECOLU  ;  B6I4R1, CDH_ECOSE  ;
DR   B1LNM1, CDH_ECOSM  ;  A4WG79, CDH_ENT38  ;  Q9Z6C1, CDH_ENTCL  ;
DR   A7MQ68, CDH_ENTS8  ;  Q9ZKX9, CDH_HELPJ  ;  Q48248, CDH_HELPY  ;
DR   B5XTD8, CDH_KLEP3  ;  P63752, CDH_MYCBO  ;  A1KKY1, CDH_MYCBP  ;
DR   C1AQK4, CDH_MYCBT  ;  B8ZRL0, CDH_MYCLB  ;  Q9CC08, CDH_MYCLE  ;
DR   A5U4X2, CDH_MYCTA  ;  P63751, CDH_MYCTU  ;  A9MI48, CDH_SALAR  ;
DR   B5QWZ7, CDH_SALEP  ;  B5RFA7, CDH_SALG2  ;  Q5PIR4, CDH_SALPA  ;
DR   A9MZF0, CDH_SALPB  ;  C0Q416, CDH_SALPC  ;  B5BJI4, CDH_SALPK  ;
DR   Q8Z2W6, CDH_SALTI  ;  P26219, CDH_SALTY  ;  Q31U72, CDH_SHIBS  ;
DR   Q83IU1, CDH_SHIFL  ;  Q3YV60, CDH_SHISS  ;  Q8ZA34, CDH_YERPE  ;
//
ID   3.6.1.27
DE   Undecaprenyl-diphosphatase.
AN   C(55)-isoprenyl diphosphatase.
AN   C(55)-isoprenyl pyrophosphatase.
AN   Isoprenyl pyrophosphatase.
CA   Undecaprenyl diphosphate + H(2)O = undecaprenyl phosphate + phosphate.
CC   -!- The undecaprenol involved is ditrans,octacis-undecaprenol.
DR   P94571, BCRC_BACSU ;  P80143, UDDP_SULAC ;  Q6FEB4, UPPP1_ACIAD;
DR   P58740, UPPP1_AGRT5;  A0R8Y3, UPPP1_BACAH;  Q81VC9, UPPP1_BACAN;
DR   P62461, UPPP1_BACC1;  Q81HV4, UPPP1_BACCR;  Q63GU6, UPPP1_BACCZ;
DR   Q9KFL5, UPPP1_BACHD;  Q6HPB7, UPPP1_BACHK;  Q65LE3, UPPP1_BACLD;
DR   Q5WH44, UPPP1_BACSK;  Q1BYF5, UPPP1_BURCA;  A0K593, UPPP1_BURCH;
DR   Q0BHM0, UPPP1_BURCM;  A3NTZ5, UPPP1_BURP0;  Q3JTI8, UPPP1_BURP1;
DR   Q63V58, UPPP1_BURPS;  Q39IU8, UPPP1_BURS3;  Q2SYE1, UPPP1_BURTA;
DR   Q13V13, UPPP1_BURXL;  Q7NYE7, UPPP1_CHRVO;  Q97LQ3, UPPP1_CLOAB;
DR   Q18BJ5, UPPP1_CLOD6;  Q4JXD8, UPPP1_CORJK;  Q831R1, UPPP1_ENTFA;
DR   Q0RKT0, UPPP1_FRAAA;  Q2JAC3, UPPP1_FRASC;  Q2W9Z8, UPPP1_MAGSA;
DR   Q04FK3, UPPP1_OENOB;  Q3IHV1, UPPP1_PSEHT;  Q3KD12, UPPP1_PSEPF;
DR   A4VLM0, UPPP1_PSEU5;  Q98DM7, UPPP1_RHILO;  Q2RYH3, UPPP1_RHORT;
DR   Q8EHD3, UPPP1_SHEON;  Q82NI4, UPPP1_STRAW;  Q9FC36, UPPP1_STRCO;
DR   Q6FDP8, UPPP2_ACIAD;  P58741, UPPP2_AGRT5;  A0R9W6, UPPP2_BACAH;
DR   Q81T84, UPPP2_BACAN;  P62462, UPPP2_BACC1;  Q81G27, UPPP2_BACCR;
DR   Q63FW2, UPPP2_BACCZ;  Q9KCP8, UPPP2_BACHD;  Q6HND2, UPPP2_BACHK;
DR   Q65FP0, UPPP2_BACLD;  Q5WCX5, UPPP2_BACSK;  Q1BXA8, UPPP2_BURCA;
DR   A0K6E4, UPPP2_BURCH;  Q0BGG1, UPPP2_BURCM;  A3NYA9, UPPP2_BURP0;
DR   Q3JPL1, UPPP2_BURP1;  Q63RM9, UPPP2_BURPS;  Q39HK8, UPPP2_BURS3;
DR   Q2SUY6, UPPP2_BURTA;  Q13W85, UPPP2_BURXL;  Q7NWQ2, UPPP2_CHRVO;
DR   Q97KF6, UPPP2_CLOAB;  Q184H7, UPPP2_CLOD6;  Q4JVN6, UPPP2_CORJK;
DR   Q5WNX2, UPPP2_ENTFA;  Q0RJJ1, UPPP2_FRAAA;  Q2J987, UPPP2_FRASC;
DR   Q2W724, UPPP2_MAGSA;  Q04D15, UPPP2_OENOB;  Q3IDA4, UPPP2_PSEHT;
DR   Q3K9J0, UPPP2_PSEPF;  A4VNS0, UPPP2_PSEU5;  Q98NJ1, UPPP2_RHILO;
DR   Q2RTE2, UPPP2_RHORT;  Q8E9K1, UPPP2_SHEON;  Q827A4, UPPP2_STRAW;
DR   Q9K407, UPPP2_STRCO;  Q6FBS3, UPPP3_ACIAD;  A0RBJ8, UPPP3_BACAH;
DR   Q81V21, UPPP3_BACAN;  P62463, UPPP3_BACC1;  Q81CP1, UPPP3_BACCR;
DR   Q63DZ3, UPPP3_BACCZ;  Q6HLG8, UPPP3_BACHK;  Q0RHR9, UPPP3_FRAAA;
DR   Q2J4I7, UPPP3_FRASC;  A0RET0, UPPP4_BACAH;  Q63AN4, UPPP4_BACCZ;
DR   Q6HI21, UPPP4_BACHK;  B0C1T8, UPPP_ACAM1 ;  A9NF64, UPPP_ACHLI ;
DR   A1TNT7, UPPP_ACIAC ;  B7GXE2, UPPP_ACIB3 ;  B7I7L7, UPPP_ACIB5 ;
DR   B2HXY4, UPPP_ACIBC ;  Q1IPW7, UPPP_ACIBL ;  B0VS31, UPPP_ACIBS ;
DR   A3M8D6, UPPP_ACIBT ;  B0VEM6, UPPP_ACIBY ;  A0LSX9, UPPP_ACIC1 ;
DR   A5FWG2, UPPP_ACICJ ;  B9MFI6, UPPP_ACIET ;  A1W560, UPPP_ACISJ ;
DR   A0KQI1, UPPP_AERHH ;  A4SHM8, UPPP_AERS4 ;  Q0VQH0, UPPP_ALCBS ;
DR   Q0AAG2, UPPP_ALHEH ;  B6EM11, UPPP_ALISL ;  A6TW45, UPPP_ALKMQ ;
DR   A8MFV5, UPPP_ALKOO ;  B4RY28, UPPP_ALTMD ;  B8J8T6, UPPP_ANAD2 ;
DR   Q2IMA5, UPPP_ANADE ;  A7H6N5, UPPP_ANADF ;  B4ULG0, UPPP_ANASK ;
DR   B9MKR9, UPPP_ANATD ;  Q3MFH9, UPPP_ANAVT ;  B7GJC8, UPPP_ANOFW ;
DR   O67939, UPPP_AQUAE ;  Q5P6K4, UPPP_AROAE ;  A1R6P8, UPPP_ARTAT ;
DR   B8H8K7, UPPP_ARTCA ;  A0JWX7, UPPP_ARTS2 ;  P39438, UPPP_AZOBR ;
DR   A1K3C4, UPPP_AZOSB ;  C1DLV7, UPPP_AZOVD ;  A7Z830, UPPP_BACA2 ;
DR   Q5LJ30, UPPP_BACFN ;  Q650L9, UPPP_BACFR ;  P94507, UPPP_BACSU ;
DR   Q8A2U3, UPPP_BACTN ;  A6KZJ8, UPPP_BACV8 ;  Q1LSL8, UPPP_BAUCH ;
DR   P60936, UPPP_BDEBA ;  B8DUF9, UPPP_BIFA0 ;  A1A1M3, UPPP_BIFAA ;
DR   B3DRX3, UPPP_BIFLD ;  Q8G6C4, UPPP_BIFLO ;  B7GR11, UPPP_BIFLS ;
DR   Q493X5, UPPP_BLOPB ;  Q2KX31, UPPP_BORA1 ;  Q0SNQ3, UPPP_BORAP ;
DR   Q7WLL4, UPPP_BORBR ;  O51273, UPPP_BORBU ;  B7J1I6, UPPP_BORBZ ;
DR   B5RL84, UPPP_BORDL ;  Q662A7, UPPP_BORGA ;  B2RZW9, UPPP_BORHD ;
DR   Q7W866, UPPP_BORPA ;  A9HXK3, UPPP_BORPD ;  Q7VXA0, UPPP_BORPE ;
DR   B5RR78, UPPP_BORRA ;  Q89WH1, UPPP_BRAJA ;  A5E8M5, UPPP_BRASB ;
DR   A4YJM2, UPPP_BRASO ;  B2SC28, UPPP_BRUA1 ;  Q2YJP6, UPPP_BRUA2 ;
DR   Q576S3, UPPP_BRUAB ;  A9MCW8, UPPP_BRUC2 ;  C0RMI1, UPPP_BRUMB ;
DR   P67384, UPPP_BRUME ;  A5VVU6, UPPP_BRUO2 ;  A9WW52, UPPP_BRUSI ;
DR   P67385, UPPP_BRUSU ;  B8D8M0, UPPP_BUCA5 ;  P57170, UPPP_BUCAI ;
DR   Q8KA52, UPPP_BUCAP ;  B8D6X4, UPPP_BUCAT ;  P59523, UPPP_BUCBP ;
DR   A3MMT3, UPPP_BURM7 ;  A2S9B4, UPPP_BURM9 ;  Q62HT6, UPPP_BURMA ;
DR   A1V1I5, UPPP_BURMS ;  A4XM19, UPPP_CALS8 ;  A7ZFX1, UPPP_CAMC1 ;
DR   A7H0X7, UPPP_CAMC5 ;  A0RQA9, UPPP_CAMFF ;  A7I0J2, UPPP_CAMHC ;
DR   A8FK06, UPPP_CAMJ8 ;  A7H1R9, UPPP_CAMJD ;  Q9PIS4, UPPP_CAMJE ;
DR   A1VXT4, UPPP_CAMJJ ;  Q5HWW4, UPPP_CAMJR ;  Q3ACY1, UPPP_CARHZ ;
DR   B8H6C3, UPPP_CAUCN ;  Q9A2G0, UPPP_CAUCR ;  B0T669, UPPP_CAUSK ;
DR   B3PI58, UPPP_CELJU ;  Q3ATC0, UPPP_CHLCH ;  B3EEG6, UPPP_CHLL2 ;
DR   B3QQ95, UPPP_CHLP8 ;  B3ELU5, UPPP_CHLPB ;  A1BE93, UPPP_CHLPD ;
DR   B3QW96, UPPP_CHLT3 ;  Q8KFJ7, UPPP_CHLTE ;  Q1QZ92, UPPP_CHRSD ;
DR   A8APU0, UPPP_CITK8 ;  A5CRN8, UPPP_CLAM3 ;  B8I004, UPPP_CLOCE ;
DR   A0Q210, UPPP_CLONN ;  Q0TRA5, UPPP_CLOP1 ;  Q8XL56, UPPP_CLOPE ;
DR   A9KNK1, UPPP_CLOPH ;  Q0STN1, UPPP_CLOPS ;  Q898B8, UPPP_CLOTE ;
DR   A3DHS8, UPPP_CLOTH ;  Q47W31, UPPP_COLP3 ;  P60937, UPPP_CORDI ;
DR   Q8FTC9, UPPP_COREF ;  A4QEA1, UPPP_CORGB ;  Q8NQC3, UPPP_CORGL ;
DR   Q9FB58, UPPP_CORST ;  Q0K7S4, UPPP_CUPNH ;  Q474P6, UPPP_CUPPJ ;
DR   Q11WJ0, UPPP_CYTH3 ;  Q478U2, UPPP_DECAR ;  C1CVN6, UPPP_DEIDV ;
DR   Q1IZI4, UPPP_DEIGD ;  Q9RX61, UPPP_DEIRA ;  B8FAZ7, UPPP_DESAA ;
DR   C6BUE1, UPPP_DESAD ;  C0QC99, UPPP_DESAH ;  B1I2Y8, UPPP_DESAP ;
DR   B8J0P3, UPPP_DESDA ;  Q310A3, UPPP_DESDG ;  B8FX50, UPPP_DESHD ;
DR   C4XT96, UPPP_DESMR ;  A8ZXM2, UPPP_DESOH ;  Q6AKL2, UPPP_DESPS ;
DR   P62464, UPPP_DESVH ;  A1VDC9, UPPP_DESVV ;  A5EW93, UPPP_DICNV ;
DR   A8LQR9, UPPP_DINSH ;  A7ZRT8, UPPP_ECO24 ;  B7UIW5, UPPP_ECO27 ;
DR   B7MAD4, UPPP_ECO45 ;  B7LGZ1, UPPP_ECO55 ;  P60933, UPPP_ECO57 ;
DR   B5YR97, UPPP_ECO5E ;  B7NJS0, UPPP_ECO7I ;  B7N061, UPPP_ECO81 ;
DR   B7LZK7, UPPP_ECO8A ;  C4ZQX4, UPPP_ECOBW ;  B1XG62, UPPP_ECODH ;
DR   A8A4L2, UPPP_ECOHS ;  A1AFX9, UPPP_ECOK1 ;  Q0TD49, UPPP_ECOL5 ;
DR   P67386, UPPP_ECOL6 ;  B1IRQ9, UPPP_ECOLC ;  P60932, UPPP_ECOLI ;
DR   B7ND46, UPPP_ECOLU ;  B6I428, UPPP_ECOSE ;  Q1R6S4, UPPP_ECOUT ;
DR   B2KE93, UPPP_ELUMP ;  A4WEI9, UPPP_ENT38 ;  A7MJT8, UPPP_ENTS8 ;
DR   Q6D159, UPPP_ERWCT ;  B2VGJ3, UPPP_ERWT9 ;  Q2N736, UPPP_ERYLH ;
DR   B7LQD5, UPPP_ESCF3 ;  B1YIX1, UPPP_EXIS2 ;  A7HJT4, UPPP_FERNB ;
DR   Q9RB37, UPPP_FLAJ1 ;  A6H239, UPPP_FLAPJ ;  Q8RIA6, UPPP_FUSNN ;
DR   C1A8L5, UPPP_GEMAT ;  Q5L3H7, UPPP_GEOKA ;  B3E340, UPPP_GEOLS ;
DR   Q39QX7, UPPP_GEOMG ;  B9M0D1, UPPP_GEOSF ;  P60938, UPPP_GEOSL ;
DR   C5D3Y4, UPPP_GEOSW ;  A4IJS3, UPPP_GEOTN ;  Q7NG92, UPPP_GLOVI ;
DR   A9HI81, UPPP_GLUDA ;  Q5FUS6, UPPP_GLUOX ;  Q0BTT3, UPPP_GRABC ;
DR   A0M5T6, UPPP_GRAFK ;  Q2SL19, UPPP_HAHCH ;  A1WUY5, UPPP_HALHL ;
DR   Q5UXT1, UPPP_HALMA ;  B8CWG2, UPPP_HALOH ;  A4G8J0, UPPP_HERAR ;
DR   Q0C618, UPPP_HYPNA ;  Q5QUY5, UPPP_IDILO ;  A6T273, UPPP_JANMA ;
DR   Q28VU8, UPPP_JANSC ;  A6W915, UPPP_KINRD ;  B5XU34, UPPP_KLEP3 ;
DR   A6TE36, UPPP_KLEP7 ;  B2GIP7, UPPP_KOCRD ;  B1L557, UPPP_KORCO ;
DR   C5CGT6, UPPP_KOSOT ;  Q03AR6, UPPP_LACC3 ;  B3WCK5, UPPP_LACCB ;
DR   Q1GB63, UPPP_LACDA ;  Q04BL0, UPPP_LACDB ;  B2GDY8, UPPP_LACF3 ;
DR   Q9CDM7, UPPP_LACLA ;  A2RNZ5, UPPP_LACLM ;  Q02VT8, UPPP_LACLS ;
DR   Q88SK7, UPPP_LACPL ;  Q38VP0, UPPP_LACSS ;  C1D4X7, UPPP_LARHH ;
DR   Q1MQW6, UPPP_LAWIP ;  B0S9E8, UPPP_LEPBA ;  Q04SA1, UPPP_LEPBJ ;
DR   Q050C7, UPPP_LEPBL ;  B0SS37, UPPP_LEPBP ;  P62465, UPPP_LEPIC ;
DR   Q8F397, UPPP_LEPIN ;  B1MW96, UPPP_LEUCK ;  Q03ZT9, UPPP_LEUMM ;
DR   B9EA92, UPPP_MACCJ ;  A0L9F4, UPPP_MAGSM ;  A1U6U1, UPPP_MARAV ;
DR   Q0ATH6, UPPP_MARMM ;  Q11CA6, UPPP_MESSB ;  A6UWS5, UPPP_META3 ;
DR   Q12UC1, UPPP_METBU ;  Q60B18, UPPP_METCA ;  Q1GY95, UPPP_METFK ;
DR   B3E171, UPPP_METI4 ;  Q8TW25, UPPP_METKA ;  A4FX27, UPPP_METM5 ;
DR   A9AAG5, UPPP_METM6 ;  A6VG87, UPPP_METM7 ;  P60942, UPPP_METMP ;
DR   A2SEL8, UPPP_METPP ;  A5UMH8, UPPP_METS3 ;  Q2NIA2, UPPP_METST ;
DR   O27479, UPPP_METTH ;  A0B9M2, UPPP_METTP ;  A6UPF1, UPPP_METVS ;
DR   C5CBT8, UPPP_MICLC ;  Q2RKY8, UPPP_MOOTA ;  A0QGK1, UPPP_MYCA1 ;
DR   Q7VEQ2, UPPP_MYCBO ;  A1KKH9, UPPP_MYCBP ;  C1AQ52, UPPP_MYCBT ;
DR   A4TB90, UPPP_MYCGI ;  B8ZRD4, UPPP_MYCLB ;  Q9CC42, UPPP_MYCLE ;
DR   B2HFY7, UPPP_MYCMM ;  P60939, UPPP_MYCPA ;  A0QZY5, UPPP_MYCS2 ;
DR   A3Q1C2, UPPP_MYCSJ ;  A1UHV6, UPPP_MYCSK ;  Q1B769, UPPP_MYCSS ;
DR   A5U4G2, UPPP_MYCTA ;  O06239, UPPP_MYCTU ;  A0PQW1, UPPP_MYCUA ;
DR   A1TAS8, UPPP_MYCVP ;  Q1CY86, UPPP_MYXXD ;  B9L7I2, UPPP_NAUPA ;
DR   Q5F6K4, UPPP_NEIG1 ;  B4RQE0, UPPP_NEIG2 ;  A9M2I7, UPPP_NEIM0 ;
DR   Q9JSY6, UPPP_NEIMA ;  Q9K0Z3, UPPP_NEIMB ;  A1KVM7, UPPP_NEIMF ;
DR   Q0AJJ0, UPPP_NITEC ;  Q82Y49, UPPP_NITEU ;  Q1QRR2, UPPP_NITHX ;
DR   Q2Y6P3, UPPP_NITMU ;  Q3J7B5, UPPP_NITOC ;  Q3SWA8, UPPP_NITWN ;
DR   Q5YVL4, UPPP_NOCFA ;  A1SJZ1, UPPP_NOCSJ ;  Q8YXJ9, UPPP_NOSS1 ;
DR   Q2G3F4, UPPP_NOVAD ;  Q8CXK0, UPPP_OCEIH ;  A6WYK2, UPPP_OCHA4 ;
DR   B6JCL3, UPPP_OLICO ;  A6LEL8, UPPP_PARD8 ;  A1AZA9, UPPP_PARDP ;
DR   A7HS58, UPPP_PARL1 ;  Q6ME04, UPPP_PARUW ;  C6DDL8, UPPP_PECCP ;
DR   Q3A6V2, UPPP_PELCD ;  Q3B5P9, UPPP_PELLD ;  B4SDS7, UPPP_PELPB ;
DR   A1AV04, UPPP_PELPD ;  A5D2Q9, UPPP_PELTS ;  Q4FNI5, UPPP_PELUB ;
DR   C0QU08, UPPP_PERMH ;  B4RCI1, UPPP_PHEZH ;  Q7N0B9, UPPP_PHOLL ;
DR   P62466, UPPP_PHOPR ;  A1VLZ3, UPPP_POLNA ;  B1XTA2, UPPP_POLNS ;
DR   Q127N8, UPPP_POLSJ ;  B2RI95, UPPP_PORG3 ;  Q7MUH6, UPPP_PORGI ;
DR   B4S3H1, UPPP_PROA2 ;  Q6A5N5, UPPP_PROAC ;  A3PCQ0, UPPP_PROM0 ;
DR   A2C1W8, UPPP_PROM1 ;  A8G4L8, UPPP_PROM2 ;  A2C666, UPPP_PROM3 ;
DR   A2BWT5, UPPP_PROM5 ;  Q31B42, UPPP_PROM9 ;  Q7VCK5, UPPP_PROMA ;
DR   Q7V8Z1, UPPP_PROMM ;  Q7V1C3, UPPP_PROMP ;  A2BQX7, UPPP_PROMS ;
DR   Q46L84, UPPP_PROMT ;  A4SDF5, UPPP_PROVI ;  Q48JI5, UPPP_PSE14 ;
DR   Q15X16, UPPP_PSEA6 ;  A6V6L2, UPPP_PSEA7 ;  B7VAE6, UPPP_PSEA8 ;
DR   Q02LA5, UPPP_PSEAB ;  Q9I2E5, UPPP_PSEAE ;  Q1I9H0, UPPP_PSEE4 ;
DR   Q4KC13, UPPP_PSEF5 ;  A4XUB9, UPPP_PSEMY ;  A5W499, UPPP_PSEP1 ;
DR   B0KUY1, UPPP_PSEPG ;  Q88IY7, UPPP_PSEPK ;  B1J8R9, UPPP_PSEPW ;
DR   Q880L3, UPPP_PSESM ;  Q4ZS30, UPPP_PSEU2 ;  Q4FR05, UPPP_PSYA2 ;
DR   Q1Q993, UPPP_PSYCK ;  A1SRC7, UPPP_PSYIN ;  A5WCV5, UPPP_PSYWF ;
DR   Q8ZYX0, UPPP_PYRAE ;  A1RQS3, UPPP_PYRIL ;  Q1LJU8, UPPP_RALME ;
DR   B2U7E0, UPPP_RALPJ ;  Q8Y1I9, UPPP_RALSO ;  A9WSJ0, UPPP_RENSM ;
DR   B3PYJ1, UPPP_RHIE6 ;  Q2KDF4, UPPP_RHIEC ;  Q1MMI4, UPPP_RHIL3 ;
DR   B5ZYG2, UPPP_RHILW ;  Q92SP2, UPPP_RHIME ;  C3MCT9, UPPP_RHISN ;
DR   Q7UNQ8, UPPP_RHOBA ;  Q21XE6, UPPP_RHOFD ;  Q2J2D8, UPPP_RHOP2 ;
DR   Q07UC1, UPPP_RHOP5 ;  P60940, UPPP_RHOPA ;  Q21C73, UPPP_RHOPB ;
DR   Q13ES7, UPPP_RHOPS ;  B3Q5X8, UPPP_RHOPT ;  A3PNJ7, UPPP_RHOS1 ;
DR   Q3IYQ0, UPPP_RHOS4 ;  A4WWA0, UPPP_RHOS5 ;  Q0SIC2, UPPP_RHOSR ;
DR   Q16DZ2, UPPP_ROSDO ;  Q1AWM0, UPPP_RUBXD ;  A1AW91, UPPP_RUTMC ;
DR   Q21II7, UPPP_SACD2 ;  A4FFN9, UPPP_SACEN ;  B5F6A1, UPPP_SALA4 ;
DR   A9MPV8, UPPP_SALAR ;  Q57JQ4, UPPP_SALCH ;  B5FHU0, UPPP_SALDC ;
DR   B4TI56, UPPP_SALHS ;  B4T675, UPPP_SALNS ;  Q5PC81, UPPP_SALPA ;
DR   C0PYX8, UPPP_SALPC ;  B5BG16, UPPP_SALPK ;  Q2S5P8, UPPP_SALRD ;
DR   B4TVT9, UPPP_SALSV ;  P67389, UPPP_SALTI ;  P67388, UPPP_SALTY ;
DR   A8GJU8, UPPP_SERP5 ;  A1S3T2, UPPP_SHEAM ;  B8EBV1, UPPP_SHEB2 ;
DR   A3D1Q8, UPPP_SHEB5 ;  A6WKK8, UPPP_SHEB8 ;  A9L5I7, UPPP_SHEB9 ;
DR   Q12KC1, UPPP_SHEDO ;  Q07YT7, UPPP_SHEFN ;  B0TIP2, UPPP_SHEHH ;
DR   A3QBM7, UPPP_SHELP ;  A8H157, UPPP_SHEPA ;  A4Y4F7, UPPP_SHEPC ;
DR   B8CJF5, UPPP_SHEPW ;  A0KZT4, UPPP_SHESA ;  A8FS68, UPPP_SHESH ;
DR   Q0HG46, UPPP_SHESM ;  Q0HSD9, UPPP_SHESR ;  A1RMH4, UPPP_SHESW ;
DR   B1KHE6, UPPP_SHEWM ;  B2U1G1, UPPP_SHIB3 ;  Q31WX8, UPPP_SHIBS ;
DR   Q0T0K6, UPPP_SHIF8 ;  P67387, UPPP_SHIFL ;  Q3YXI5, UPPP_SHISS ;
DR   Q5LLZ3, UPPP_SILPO ;  Q1GCR3, UPPP_SILST ;  A6UFC2, UPPP_SINMW ;
DR   Q2NWE3, UPPP_SODGM ;  Q01WE6, UPPP_SOLUE ;  A9GC83, UPPP_SORC5 ;
DR   Q1GR76, UPPP_SPHAL ;  A5V412, UPPP_SPHWW ;  A7WZF5, UPPP_STAA1 ;
DR   A6TZG1, UPPP_STAA2 ;  Q2FIV6, UPPP_STAA3 ;  Q2G0B4, UPPP_STAA8 ;
DR   A5IQN7, UPPP_STAA9 ;  Q2YSP8, UPPP_STAAB ;  Q5HHY5, UPPP_STAAC ;
DR   A6QEZ2, UPPP_STAAE ;  P67390, UPPP_STAAM ;  P67391, UPPP_STAAN ;
DR   Q6GIV9, UPPP_STAAR ;  Q6GBE7, UPPP_STAAS ;  A8YZV4, UPPP_STAAT ;
DR   Q9KIN5, UPPP_STAAU ;  Q8NXQ4, UPPP_STAAW ;  B9DK59, UPPP_STACT ;
DR   Q5HR54, UPPP_STAEQ ;  Q8CTJ6, UPPP_STAES ;  Q4L4A6, UPPP_STAHJ ;
DR   Q49VN0, UPPP_STAS1 ;  Q3K3N4, UPPP_STRA1 ;  Q8E7M0, UPPP_STRA3 ;
DR   Q8E260, UPPP_STRA5 ;  C0M8J5, UPPP_STRE4 ;  B4U4X0, UPPP_STREM ;
DR   A8AYY7, UPPP_STRGC ;  B1W4P7, UPPP_STRGG ;  B4SRU3, UPPP_STRM5 ;
DR   B2FHB6, UPPP_STRMK ;  Q8CWZ1, UPPP_STRMU ;  P67392, UPPP_STRP1 ;
DR   Q04M23, UPPP_STRP2 ;  P0DH30, UPPP_STRP3 ;  B5E1R8, UPPP_STRP4 ;
DR   Q5XDV8, UPPP_STRP6 ;  C1C5J2, UPPP_STRP7 ;  P67394, UPPP_STRP8 ;
DR   Q1JDJ9, UPPP_STRPB ;  Q1JNH1, UPPP_STRPC ;  Q1JIM0, UPPP_STRPD ;
DR   Q1J8H6, UPPP_STRPF ;  A2RCI8, UPPP_STRPG ;  B1I9P6, UPPP_STRPI ;
DR   B8ZLV4, UPPP_STRPJ ;  Q48VA9, UPPP_STRPM ;  P60934, UPPP_STRPN ;
DR   P0DH31, UPPP_STRPQ ;  B2IM77, UPPP_STRPS ;  B5XJR7, UPPP_STRPZ ;
DR   P60935, UPPP_STRR6 ;  A4W3V2, UPPP_STRS2 ;  C0MG10, UPPP_STRS7 ;
DR   A3CQ79, UPPP_STRSV ;  A4VXK6, UPPP_STRSY ;  Q5M1R0, UPPP_STRT1 ;
DR   Q5M6A1, UPPP_STRT2 ;  Q03MN6, UPPP_STRTD ;  C1CCM1, UPPP_STRZJ ;
DR   C1CIV9, UPPP_STRZP ;  C1CPW6, UPPP_STRZT ;  Q30UH8, UPPP_SULDN ;
DR   C4KFQ2, UPPP_SULIK ;  C3MWB6, UPPP_SULIM ;  C3NJZ2, UPPP_SULIN ;
DR   C3NBN0, UPPP_SULIY ;  A6QA78, UPPP_SULNB ;  Q97X94, UPPP_SULSO ;
DR   B2V5I7, UPPP_SULSY ;  Q96ZM1, UPPP_SULTO ;  Q67LG6, UPPP_SYMTH ;
DR   Q2LXE8, UPPP_SYNAS ;  Q31LS2, UPPP_SYNE7 ;  A0LG71, UPPP_SYNFM ;
DR   Q2JXZ9, UPPP_SYNJA ;  Q2JJZ9, UPPP_SYNJB ;  Q5N052, UPPP_SYNP6 ;
DR   A5GNW2, UPPP_SYNPW ;  Q7U482, UPPP_SYNPX ;  A5GQQ0, UPPP_SYNR3 ;
DR   Q0I740, UPPP_SYNS3 ;  Q3AZZ7, UPPP_SYNS9 ;  Q3AH68, UPPP_SYNSC ;
DR   Q0AXH9, UPPP_SYNWW ;  Q55684, UPPP_SYNY3 ;  C5BRP6, UPPP_TERTT ;
DR   B7IFS1, UPPP_THEAB ;  Q8DKW4, UPPP_THEEB ;  Q47NU8, UPPP_THEFY ;
DR   A6LJI3, UPPP_THEM4 ;  Q9WZZ5, UPPP_THEMA ;  A5IIP0, UPPP_THEP1 ;
DR   B0K909, UPPP_THEP3 ;  B0K0H2, UPPP_THEPX ;  B9KYE6, UPPP_THERP ;
DR   B1LC41, UPPP_THESQ ;  P62467, UPPP_THET2 ;  Q5SLX1, UPPP_THET8 ;
DR   Q8RB29, UPPP_THETN ;  B5YID8, UPPP_THEYD ;  Q31EL5, UPPP_THICR ;
DR   Q3SFG5, UPPP_THIDA ;  B8GUR7, UPPP_THISH ;  P60941, UPPP_TREDE ;
DR   Q10VH5, UPPP_TRIEI ;  Q83HQ7, UPPP_TROW8 ;  Q83GH4, UPPP_TROWT ;
DR   C5CTM8, UPPP_VARPS ;  A1WK80, UPPP_VEREI ;  A5CWY7, UPPP_VESOH ;
DR   A5F9D4, UPPP_VIBC3 ;  Q9KUJ4, UPPP_VIBCH ;  C3LS16, UPPP_VIBCM ;
DR   Q5E2K6, UPPP_VIBF1 ;  B5FB78, UPPP_VIBFM ;  A7MWQ3, UPPP_VIBHB ;
DR   Q87SL0, UPPP_VIBPA ;  B7VIW0, UPPP_VIBSL ;  Q8DEG8, UPPP_VIBVU ;
DR   Q7MNZ4, UPPP_VIBVY ;  Q8D281, UPPP_WIGBR ;  Q7M8Z9, UPPP_WOLSU ;
DR   Q8PQW6, UPPP_XANAC ;  Q3BZ95, UPPP_XANC5 ;  Q4V093, UPPP_XANC8 ;
DR   Q8PDZ9, UPPP_XANCP ;  Q2NXJ3, UPPP_XANOM ;  B2SHN5, UPPP_XANOP ;
DR   Q5GU80, UPPP_XANOR ;  Q9PCE0, UPPP_XYLFA ;  Q87CN8, UPPP_XYLFT ;
DR   A1JQW4, UPPP_YERE8 ;  A7FE74, UPPP_YERP3 ;  Q1C369, UPPP_YERPA ;
DR   B2K2I0, UPPP_YERPB ;  Q8ZI65, UPPP_YERPE ;  A9R7E0, UPPP_YERPG ;
DR   Q1CMD9, UPPP_YERPN ;  A4THT4, UPPP_YERPP ;  Q665U8, UPPP_YERPS ;
DR   B1JM21, UPPP_YERPY ;  Q9RNL1, UPPP_ZYMMO ;  P75806, YBJG_ECOLI ;
//
ID   3.6.1.28
DE   Thiamine-triphosphatase.
AN   ThTPase.
CA   Thiamine triphosphate + H(2)O = thiamine diphosphate + phosphate.
DR   Q8MKF1, THTPA_BOVIN;  Q9BU02, THTPA_HUMAN;  Q9BGW0, THTPA_MACFA;
DR   Q8JZL3, THTPA_MOUSE;  Q8CGV7, THTPA_RAT  ;
//
ID   3.6.1.29
DE   Bis(5'-adenosyl)-triphosphatase.
AN   AP(3)A hydrolase.
AN   AP(3)Aase.
AN   AP3A hydrolase.
AN   AP3Aase.
AN   Diadenosine 5',5'''-P(1),P(3)-triphosphate hydrolase.
AN   Dinucleosidetriphosphatase.
CA   P(1)-P(3)-bis(5'-adenosyl) triphosphate + H(2)O = ADP + AMP.
PR   PROSITE; PDOC00694;
DR   Q1KZG4, FHIT_BOVIN ;  Q86KK2, FHIT_DICDI ;  P49789, FHIT_HUMAN ;
DR   O89106, FHIT_MOUSE ;  Q9JIX3, FHIT_RAT   ;  B3LFZ1, HNT2_YEAS1 ;
DR   C7GQV5, HNT2_YEAS2 ;  B5VGI4, HNT2_YEAS6 ;  A6ZYQ3, HNT2_YEAS7 ;
DR   C8Z5L6, HNT2_YEAS8 ;  P49775, HNT2_YEAST ;  O76463, NFT1_CAEEL ;
DR   O76464, NFT1_DROME ;
//
ID   3.6.1.30
DE   M(7)G(5')pppN diphosphatase.
AN   Decapase.
AN   M(7)G(5')pppN pyrophosphatase.
CA   7-methylguanosine 5'-triphospho-5'-polynucleotide + H(2)O =
CA   7-methylguanosine 5'-phosphate + polynucleotide.
//
ID   3.6.1.31
DE   Phosphoribosyl-ATP diphosphatase.
AN   Phosphoribosyl-ATP pyrophosphatase.
AN   Phosphoribosyladenosine triphosphate pyrophosphatase.
CA   1-(5-phosphoribosyl)-ATP + H(2)O = 1-(5-phosphoribosyl)-AMP +
CA   diphosphate.
CC   -!- The Neurospora crassa enzyme also catalyzes the reactions of
CC       EC 1.1.1.23 and EC 3.5.4.19.
DR   Q89WM3, HIS21_BRAJA;  P60538, HIS21_RHOPA;  Q938W0, HIS22_BRAJA;
DR   P60539, HIS22_RHOPA;  A1TL08, HIS2_ACIAC ;  A5FYE6, HIS2_ACICJ ;
DR   A1W446, HIS2_ACISJ ;  B9JG64, HIS2_AGRRK ;  Q8UJ91, HIS2_AGRT5 ;
DR   B9JXX0, HIS2_AGRVS ;  Q0VMA1, HIS2_ALCBS ;  Q0A5D4, HIS2_ALHEH ;
DR   O67780, HIS2_AQUAE ;  O82768, HIS2_ARATH ;  Q5P797, HIS2_AROAE ;
DR   A1R5R9, HIS2_ARTAT ;  B8H6U0, HIS2_ARTCA ;  A0JVK3, HIS2_ARTS2 ;
DR   P26722, HIS2_AZOBR ;  A8HYT3, HIS2_AZOC5 ;  Q43926, HIS2_AZOCH ;
DR   A1KAV2, HIS2_AZOSB ;  C1DHS6, HIS2_AZOVD ;  C3P507, HIS2_BACAA ;
DR   C3L9P5, HIS2_BACAC ;  A0RBM4, HIS2_BACAH ;  P60534, HIS2_BACAN ;
DR   B7JFZ7, HIS2_BACC0 ;  P62346, HIS2_BACC1 ;  B7INA5, HIS2_BACC2 ;
DR   C1EMQ9, HIS2_BACC3 ;  B7HHG7, HIS2_BACC4 ;  B7HKD6, HIS2_BACC7 ;
DR   A7GMV2, HIS2_BACCN ;  B9IV02, HIS2_BACCQ ;  Q81G00, HIS2_BACCR ;
DR   Q63DW6, HIS2_BACCZ ;  Q9K6Z7, HIS2_BACHD ;  Q6HLE1, HIS2_BACHK ;
DR   O34912, HIS2_BACSU ;  Q8A7Z7, HIS2_BACTN ;  A9VLH9, HIS2_BACWK ;
DR   C5C6A2, HIS2_BEUC1 ;  B8DUC2, HIS2_BIFA0 ;  A1A1J2, HIS2_BIFAA ;
DR   B3DS06, HIS2_BIFLD ;  Q8G694, HIS2_BIFLO ;  B7GRM5, HIS2_BIFLS ;
DR   Q7VQW4, HIS2_BLOFL ;  Q2KTS9, HIS2_BORA1 ;  Q7WDX7, HIS2_BORBR ;
DR   Q7W2X7, HIS2_BORPA ;  Q7VSY4, HIS2_BORPE ;  B2S985, HIS2_BRUA1 ;
DR   Q2YQY7, HIS2_BRUA2 ;  Q57AH2, HIS2_BRUAB ;  A9M9S0, HIS2_BRUC2 ;
DR   C0RFX4, HIS2_BRUMB ;  P64351, HIS2_BRUME ;  A5VT44, HIS2_BRUO2 ;
DR   B0CJI7, HIS2_BRUSI ;  P64352, HIS2_BRUSU ;  P57207, HIS2_BUCAI ;
DR   Q9ZHE0, HIS2_BUCAP ;  Q89AX6, HIS2_BUCBP ;  B1YRW3, HIS2_BURA4 ;
DR   Q1BS33, HIS2_BURCA ;  B1JUA7, HIS2_BURCC ;  A0K3W0, HIS2_BURCH ;
DR   B4E643, HIS2_BURCJ ;  Q0BIW2, HIS2_BURCM ;  Q845U5, HIS2_BURM1 ;
DR   A3MPU2, HIS2_BURM7 ;  A2S756, HIS2_BURM9 ;  Q62GE7, HIS2_BURMA ;
DR   A1V8H7, HIS2_BURMS ;  A3P025, HIS2_BURP0 ;  Q3JN04, HIS2_BURP1 ;
DR   A3NE91, HIS2_BURP6 ;  Q63Q94, HIS2_BURPS ;  Q39K83, HIS2_BURS3 ;
DR   Q2SUB0, HIS2_BURTA ;  A4JAX1, HIS2_BURVG ;  Q13TR2, HIS2_BURXL ;
DR   Q9PM71, HIS2_CAMJE ;  O74712, HIS2_CANAL ;  B8GW16, HIS2_CAUCN ;
DR   Q9A228, HIS2_CAUCR ;  B0T797, HIS2_CAUSK ;  Q1R002, HIS2_CHRSD ;
DR   Q7P0E6, HIS2_CHRVO ;  A5CRW4, HIS2_CLAM3 ;  B0REU9, HIS2_CLAMS ;
DR   Q97KH6, HIS2_CLOAB ;  A7FU84, HIS2_CLOB1 ;  A5I248, HIS2_CLOBH ;
DR   C1FN44, HIS2_CLOBJ ;  B1ILB2, HIS2_CLOBK ;  A0PXP9, HIS2_CLONN ;
DR   Q898L3, HIS2_CLOTE ;  C3PG92, HIS2_CORA7 ;  P60535, HIS2_CORDI ;
DR   Q8FTD4, HIS2_COREF ;  A4QE91, HIS2_CORGB ;  Q9Z471, HIS2_CORGL ;
DR   Q0K695, HIS2_CUPNH ;  Q46WM0, HIS2_CUPPJ ;  Q47AM5, HIS2_DECAR ;
DR   Q9RWD6, HIS2_DEIRA ;  A8LSV9, HIS2_DINSH ;  Q9S5G3, HIS2_ECO57 ;
DR   Q8FG47, HIS2_ECOL6 ;  P06989, HIS2_ECOLI ;  Q2N8I9, HIS2_ERYLH ;
DR   B3E616, HIS2_GEOLS ;  Q39YP1, HIS2_GEOMG ;  B9M0M1, HIS2_GEOSF ;
DR   P60536, HIS2_GEOSL ;  Q7NLB5, HIS2_GLOVI ;  Q5FTN2, HIS2_GLUOX ;
DR   Q0BPX5, HIS2_GRABC ;  P44434, HIS2_HAEIN ;  Q2SN16, HIS2_HAHCH ;
DR   A1WW04, HIS2_HALHL ;  Q5UZW6, HIS2_HALMA ;  B0R877, HIS2_HALS3 ;
DR   Q9HMD4, HIS2_HALSA ;  Q18KL7, HIS2_HALWD ;  Q7VJ02, HIS2_HELHP ;
DR   A4G9I4, HIS2_HERAR ;  A8A8G1, HIS2_IGNH4 ;  A6T374, HIS2_JANMA ;
DR   Q28NJ9, HIS2_JANSC ;  O24714, HIS2_KLEPN ;  O13471, HIS2_KLULA ;
DR   B2GGU7, HIS2_KOCRD ;  Q039B7, HIS2_LACC3 ;  B3WEC9, HIS2_LACCB ;
DR   B2GBR7, HIS2_LACF3 ;  Q02130, HIS2_LACLA ;  Q88UE5, HIS2_LACPL ;
DR   Q6AF75, HIS2_LEIXX ;  B0SDY7, HIS2_LEPBA ;  Q04V97, HIS2_LEPBJ ;
DR   Q04Y79, HIS2_LEPBL ;  B0SMB9, HIS2_LEPBP ;  P62347, HIS2_LEPIC ;
DR   Q8EXX8, HIS2_LEPIN ;  Q03VY2, HIS2_LEUMM ;  Q92E90, HIS2_LISIN ;
DR   C1L0J0, HIS2_LISMC ;  Q722Y9, HIS2_LISMF ;  B8DA64, HIS2_LISMH ;
DR   Q8Y9G7, HIS2_LISMO ;  A0AG13, HIS2_LISW6 ;  Q2VYJ1, HIS2_MAGSA ;
DR   A0LCF5, HIS2_MAGSM ;  A1U671, HIS2_MARAV ;  Q11CK6, HIS2_MESSB ;
DR   A6UTD9, HIS2_META3 ;  P58834, HIS2_METAC ;  A7IA25, HIS2_METB6 ;
DR   Q46AJ8, HIS2_METBF ;  Q12UV8, HIS2_METBU ;  Q603K5, HIS2_METCA ;
DR   Q1H4R0, HIS2_METFK ;  Q57750, HIS2_METJA ;  P58835, HIS2_METKA ;
DR   A2ST94, HIS2_METLZ ;  A4G0E2, HIS2_METM5 ;  A9A8P0, HIS2_METM6 ;
DR   A6VI38, HIS2_METM7 ;  Q8PUG2, HIS2_METMA ;  A3CWF5, HIS2_METMJ ;
DR   P62348, HIS2_METMP ;  B8IPH2, HIS2_METNO ;  B8GKC9, HIS2_METPE ;
DR   A2SE11, HIS2_METPP ;  B1M0Q0, HIS2_METRJ ;  A5UM80, HIS2_METS3 ;
DR   B0UHR4, HIS2_METS4 ;  A4YI36, HIS2_METS5 ;  Q2NHF0, HIS2_METST ;
DR   O27344, HIS2_METTH ;  A6UR44, HIS2_METVS ;  C5CBJ9, HIS2_MICLC ;
DR   A0QFA4, HIS2_MYCA1 ;  B1MPG1, HIS2_MYCA9 ;  P0A5B2, HIS2_MYCBO ;
DR   A1KKG5, HIS2_MYCBP ;  C1AQ38, HIS2_MYCBT ;  A4TB82, HIS2_MYCGI ;
DR   B8ZRE4, HIS2_MYCLB ;  Q49786, HIS2_MYCLE ;  B2HFX5, HIS2_MYCMM ;
DR   P60537, HIS2_MYCPA ;  A0QZX2, HIS2_MYCS2 ;  A3Q1B0, HIS2_MYCSJ ;
DR   A1UHU4, HIS2_MYCSK ;  Q1B781, HIS2_MYCSS ;  A5U4E8, HIS2_MYCTA ;
DR   P0A5B1, HIS2_MYCTU ;  A0PQV0, HIS2_MYCUA ;  A1TAR6, HIS2_MYCVP ;
DR   Q3IU57, HIS2_NATPD ;  Q5FA47, HIS2_NEIG1 ;  Q9JVJ9, HIS2_NEIMA ;
DR   Q9K0J4, HIS2_NEIMB ;  A1KSL1, HIS2_NEIMF ;  P07685, HIS2_NEUCR ;
DR   Q0AET9, HIS2_NITEC ;  Q82WM7, HIS2_NITEU ;  Q1QRW9, HIS2_NITHX ;
DR   Q2YAV2, HIS2_NITMU ;  Q3J6P9, HIS2_NITOC ;  Q3SWF2, HIS2_NITWN ;
DR   Q5YUV8, HIS2_NOCFA ;  A1SJH0, HIS2_NOCSJ ;  Q8YS28, HIS2_NOSS1 ;
DR   Q2G9L7, HIS2_NOVAD ;  Q8CXM8, HIS2_OCEIH ;  A6WX51, HIS2_OCHA4 ;
DR   A1B389, HIS2_PARDP ;  A7HSG7, HIS2_PARL1 ;  Q9CLL8, HIS2_PASMU ;
DR   A1ATH9, HIS2_PELPD ;  A5CZ71, HIS2_PELTS ;  Q7N6I6, HIS2_PHOLL ;
DR   P62349, HIS2_PHOPR ;  P45353, HIS2_PICPA ;  Q12FC5, HIS2_POLSJ ;
DR   Q6A7U7, HIS2_PROAC ;  Q7VD07, HIS2_PROMA ;  Q7TV28, HIS2_PROMM ;
DR   Q7TUC7, HIS2_PROMP ;  Q48PJ8, HIS2_PSE14 ;  A6VDJ0, HIS2_PSEA7 ;
DR   B7V3G0, HIS2_PSEA8 ;  Q02EV0, HIS2_PSEAB ;  Q9HUB6, HIS2_PSEAE ;
DR   Q1I3S6, HIS2_PSEE4 ;  Q4KJL6, HIS2_PSEF5 ;  C3K8U0, HIS2_PSEFS ;
DR   A4XPM3, HIS2_PSEMY ;  A5WA49, HIS2_PSEP1 ;  Q3KJC9, HIS2_PSEPF ;
DR   B0KM40, HIS2_PSEPG ;  Q88D14, HIS2_PSEPK ;  B1J2S4, HIS2_PSEPW ;
DR   Q87UY8, HIS2_PSESM ;  Q4ZZG7, HIS2_PSEU2 ;  A4VGE1, HIS2_PSEU5 ;
DR   Q8ZY18, HIS2_PYRAE ;  A4WHB4, HIS2_PYRAR ;  A3MSF6, HIS2_PYRCJ ;
DR   P58853, HIS2_PYRFU ;  A1RTU9, HIS2_PYRIL ;  Q1LIB4, HIS2_RALME ;
DR   B2UEE3, HIS2_RALPJ ;  Q8XV87, HIS2_RALSO ;  B3PWH8, HIS2_RHIE6 ;
DR   Q2KE62, HIS2_RHIEC ;  Q1MNF9, HIS2_RHIL3 ;  Q98CT0, HIS2_RHILO ;
DR   B5ZV90, HIS2_RHILW ;  Q92TB4, HIS2_RHIME ;  C3MBC0, HIS2_RHISN ;
DR   Q7URL1, HIS2_RHOBA ;  O30723, HIS2_RHOCB ;  C0ZZV8, HIS2_RHOE4 ;
DR   Q21U89, HIS2_RHOFD ;  C1ASQ8, HIS2_RHOOB ;  Q2RNA8, HIS2_RHORT ;
DR   A3PI61, HIS2_RHOS1 ;  P50935, HIS2_RHOS4 ;  A4WUS9, HIS2_RHOS5 ;
DR   B9KPC7, HIS2_RHOSK ;  Q0SIE8, HIS2_RHOSR ;  Q162Q0, HIS2_ROSDO ;
DR   A1AVW2, HIS2_RUTMC ;  Q12670, HIS2_SACBA ;  Q21FP9, HIS2_SACD2 ;
DR   A4FBW7, HIS2_SACEN ;  Q2S4L5, HIS2_SALRD ;  Q8Z5J6, HIS2_SALTI ;
DR   P10367, HIS2_SALTY ;  O59667, HIS2_SCHPO ;  Q8EFB6, HIS2_SHEON ;
DR   P37793, HIS2_SHIFL ;  Q3Z0F9, HIS2_SHISS ;  Q5LUA0, HIS2_SILPO ;
DR   Q1GEZ2, HIS2_SILST ;  A6UEK2, HIS2_SINMW ;  Q1GQI3, HIS2_SPHAL ;
DR   A5V9F7, HIS2_SPHWW ;  Q5HCM5, HIS2_STAAC ;  P64355, HIS2_STAAM ;
DR   P64356, HIS2_STAAN ;  Q6GDD2, HIS2_STAAR ;  Q6G603, HIS2_STAAS ;
DR   Q8NUI4, HIS2_STAAW ;  Q5HKP3, HIS2_STAEQ ;  Q8CQ91, HIS2_STAES ;
DR   Q827L8, HIS2_STRAW ;  Q9EWK0, HIS2_STRCO ;  A8AY22, HIS2_STRGC ;
DR   B1W4A6, HIS2_STRGG ;  A3CNS8, HIS2_STRSV ;  Q03K84, HIS2_STRTD ;
DR   Q4J8I7, HIS2_SULAC ;  C3N6A4, HIS2_SULIA ;  C4KHR8, HIS2_SULIK ;
DR   C3MQI3, HIS2_SULIL ;  C3MW61, HIS2_SULIM ;  C3NGY3, HIS2_SULIN ;
DR   C3NER1, HIS2_SULIY ;  O33776, HIS2_SULSO ;  Q970Y8, HIS2_SULTO ;
DR   Q7U635, HIS2_SYNPX ;  P74755, HIS2_SYNY3 ;  C6AR38, HIS2_TERTT ;
DR   Q8DM88, HIS2_THEEB ;  Q47TK1, HIS2_THEFY ;  Q9X0C5, HIS2_THEMA ;
DR   B1YAN0, HIS2_THENV ;  Q9RPQ3, HIS2_THEP3 ;  P62350, HIS2_THET2 ;
DR   Q8R886, HIS2_THETN ;  Q31E63, HIS2_THICR ;  Q3SI69, HIS2_THIDA ;
DR   Q0W1M3, HIS2_UNCMA ;  C5CQK2, HIS2_VARPS ;  A1WFS9, HIS2_VEREI ;
DR   A5CXC6, HIS2_VESOH ;  Q9KSW7, HIS2_VIBCH ;  Q87QK5, HIS2_VIBPA ;
DR   Q8D8Q6, HIS2_VIBVU ;  Q7MLS0, HIS2_VIBVY ;  Q7MAQ8, HIS2_WOLSU ;
DR   Q8PLG5, HIS2_XANAC ;  Q8P9N8, HIS2_XANCP ;  Q9PBD1, HIS2_XYLFA ;
DR   Q87C35, HIS2_XYLFT ;  P00815, HIS2_YEAST ;  Q8ZFY1, HIS2_YERPE ;
DR   Q5NMD7, HIS2_ZYMMO ;
//
ID   3.6.1.32
DE   Transferred entry: 3.6.4.1.
//
ID   3.6.1.33
DE   Transferred entry: 3.6.4.2.
//
ID   3.6.1.34
DE   Transferred entry: 3.6.3.14.
//
ID   3.6.1.35
DE   Transferred entry: 3.6.3.6.
//
ID   3.6.1.36
DE   Transferred entry: 3.6.3.10.
//
ID   3.6.1.37
DE   Transferred entry: 3.6.3.9.
//
ID   3.6.1.38
DE   Transferred entry: 3.6.3.8.
//
ID   3.6.1.39
DE   Thymidine-triphosphatase.
CA   dTTP + H(2)O = dTDP + phosphate.
CC   -!- Also acts, more slowly, on dUTP and UTP.
//
ID   3.6.1.40
DE   Guanosine-5'-triphosphate,3'-diphosphate diphosphatase.
AN   Guanosine pentaphosphate phosphohydrolase.
AN   Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase.
AN   pppGpp 5'-phosphohydrolase.
CA   Guanosine 5'-triphosphate,3'-diphosphate + H(2)O = guanosine
CA   3',5'-bis(diphosphate) + phosphate.
CC   -!- Also hydrolyzes other guanosine 5'-triphosphate derivatives with at
CC       least one unsubstituted phosphate group on the 3'-position, but not
CC       GTP, ATP or adenosine 5'-triphosphate,3'-diphosphate.
DR   A0KEG8, GPPA_AERHH ;  A4STJ8, GPPA_AERS4 ;  A8ACT2, GPPA_CITK8 ;
DR   A7ZTY0, GPPA_ECO24 ;  B7UMN4, GPPA_ECO27 ;  B7MGI9, GPPA_ECO45 ;
DR   B7L8C0, GPPA_ECO55 ;  Q8XAT5, GPPA_ECO57 ;  B5YY27, GPPA_ECO5E ;
DR   B7NTG3, GPPA_ECO7I ;  B7N272, GPPA_ECO81 ;  B7M5C6, GPPA_ECO8A ;
DR   C4ZZ47, GPPA_ECOBW ;  B1X9Z3, GPPA_ECODH ;  A8A6N3, GPPA_ECOHS ;
DR   A1AHU9, GPPA_ECOK1 ;  Q8FBR0, GPPA_ECOL6 ;  B1IWC1, GPPA_ECOLC ;
DR   P25552, GPPA_ECOLI ;  B7NF84, GPPA_ECOLU ;  B6I4B5, GPPA_ECOSE ;
DR   B1LLV2, GPPA_ECOSM ;  Q1R4G0, GPPA_ECOUT ;  A4WG31, GPPA_ENT38 ;
DR   A7MQI3, GPPA_ENTS8 ;  Q6CZD8, GPPA_ERWCT ;  B2VG72, GPPA_ERWT9 ;
DR   B7LU76, GPPA_ESCF3 ;  B5XYZ0, GPPA_KLEP3 ;  A6TGG8, GPPA_KLEP7 ;
DR   C6DHF6, GPPA_PECCP ;  Q7MYL1, GPPA_PHOLL ;  Q6LLL4, GPPA_PHOPR ;
DR   B4F1V2, GPPA_PROMH ;  Q15N19, GPPA_PSEA6 ;  Q3IDD5, GPPA_PSEHT ;
DR   B5EZ39, GPPA_SALA4 ;  A9MJ30, GPPA_SALAR ;  Q57HT7, GPPA_SALCH ;
DR   B5FN73, GPPA_SALDC ;  B5QVH1, GPPA_SALEP ;  B5RFS4, GPPA_SALG2 ;
DR   B4TB12, GPPA_SALHS ;  B4SZ25, GPPA_SALNS ;  Q5PKK4, GPPA_SALPA ;
DR   A9MXF2, GPPA_SALPB ;  C0Q2V8, GPPA_SALPC ;  B5BIS8, GPPA_SALPK ;
DR   B4TNT2, GPPA_SALSV ;  P0A268, GPPA_SALTI ;  P0A267, GPPA_SALTY ;
DR   A8G827, GPPA_SERP5 ;  B2TU13, GPPA_SHIB3 ;  Q31UK6, GPPA_SHIBS ;
DR   Q329V7, GPPA_SHIDS ;  Q0SYW9, GPPA_SHIF8 ;  Q83PI3, GPPA_SHIFL ;
DR   Q3YVI5, GPPA_SHISS ;  Q2NQB1, GPPA_SODGM ;  A5F3R3, GPPA_VIBC3 ;
DR   Q9KV53, GPPA_VIBCH ;  C3LQR0, GPPA_VIBCM ;  Q5E8U7, GPPA_VIBF1 ;
DR   B5FF86, GPPA_VIBFM ;  A7MXT2, GPPA_VIBHB ;  Q87KH4, GPPA_VIBPA ;
DR   B7VMF0, GPPA_VIBSL ;  Q8DDN5, GPPA_VIBVU ;  Q7MGP6, GPPA_VIBVY ;
DR   A1JI66, GPPA_YERE8 ;  A7FD46, GPPA_YERP3 ;  B2K045, GPPA_YERPB ;
DR   Q74R94, GPPA_YERPE ;  A9R8H6, GPPA_YERPG ;  A4TRC9, GPPA_YERPP ;
DR   Q66G20, GPPA_YERPS ;  B1JQ12, GPPA_YERPY ;
//
ID   3.6.1.41
DE   Bis(5'-nucleosyl)-tetraphosphatase (symmetrical).
AN   Ap(4)A hydrolase.
AN   Ap4A hydrolase.
AN   Diadenosine 5',5'''-P(1),P(4)-tetraphosphate pyrophosphohydrolase.
AN   Diadenosinetetraphosphatase (symmetrical).
AN   Dinucleosidetetraphosphatase (symmetrical).
CA   P(1),P(4)-bis(5'-adenosyl) tetraphosphate + H(2)O = 2 ADP.
CC   -!- Also acts on bis(5'-guanosyl) tetraphosphate and bis(5'-adenosyl)
CC       pentaphosphate, and, more slowly, on some other polyphosphates,
CC       forming a nucleoside bisphosphate as one product in all cases (cf.
CC       EC 3.6.1.17).
DR   A1TLA3, APAH_ACIAC ;  B9MFH8, APAH_ACIET ;  A1W551, APAH_ACISJ ;
DR   A3N0C2, APAH_ACTP2 ;  B3GXJ7, APAH_ACTP7 ;  B0BP40, APAH_ACTPJ ;
DR   A6VMA9, APAH_ACTSZ ;  A0KGT6, APAH_AERHH ;  A4SR08, APAH_AERS4 ;
DR   O52655, APAH_AGGAC ;  Q0AC59, APAH_ALHEH ;  B6EL47, APAH_ALISL ;
DR   Q5P6P9, APAH_AROAE ;  C1DIX1, APAH_AZOVD ;  Q1LSS3, APAH_BAUCH ;
DR   Q7WF80, APAH_BORBR ;  Q7W3V0, APAH_BORPA ;  A9I1T6, APAH_BORPD ;
DR   Q7W041, APAH_BORPE ;  B8D8U3, APAH_BUCA5 ;  P57242, APAH_BUCAI ;
DR   Q8K9Z9, APAH_BUCAP ;  B8D747, APAH_BUCAT ;  Q89AV3, APAH_BUCBP ;
DR   A3MMA4, APAH_BURM7 ;  A2S9T5, APAH_BURM9 ;  Q9AEV8, APAH_BURMA ;
DR   A1V209, APAH_BURMS ;  A3NYF9, APAH_BURP0 ;  Q3JPG7, APAH_BURP1 ;
DR   A3NCP7, APAH_BURP6 ;  B2JFC8, APAH_BURP8 ;  O69115, APAH_BURPS ;
DR   Q2SYI5, APAH_BURTA ;  B3PKV6, APAH_CELJU ;  Q1QZ29, APAH_CHRSD ;
DR   Q7NQS0, APAH_CHRVO ;  A8ALQ2, APAH_CITK8 ;  Q47VJ7, APAH_COLP3 ;
DR   B6J646, APAH_COXB1 ;  B6J3B1, APAH_COXB2 ;  A9KH04, APAH_COXBN ;
DR   A9N9I1, APAH_COXBR ;  Q83AB7, APAH_COXBU ;  Q478S1, APAH_DECAR ;
DR   A9BVD2, APAH_DELAS ;  A7ZHE2, APAH_ECO24 ;  B7UI97, APAH_ECO27 ;
DR   B7MAH4, APAH_ECO45 ;  B7L4H2, APAH_ECO55 ;  Q8XA15, APAH_ECO57 ;
DR   B5YZ87, APAH_ECO5E ;  B7NHF5, APAH_ECO7I ;  B7MNQ8, APAH_ECO81 ;
DR   B7M0E6, APAH_ECO8A ;  C4ZPX5, APAH_ECOBW ;  B1XC50, APAH_ECODH ;
DR   A7ZW01, APAH_ECOHS ;  A1A798, APAH_ECOK1 ;  Q0TLT8, APAH_ECOL5 ;
DR   Q8FL98, APAH_ECOL6 ;  B1IRC7, APAH_ECOLC ;  P05637, APAH_ECOLI ;
DR   B7N7S4, APAH_ECOLU ;  B6HZ30, APAH_ECOSE ;  B1LFY5, APAH_ECOSM ;
DR   Q1RGE8, APAH_ECOUT ;  C5B7N9, APAH_EDWI9 ;  A4W6F5, APAH_ENT38 ;
DR   P27510, APAH_ENTAE ;  A7MIB2, APAH_ENTS8 ;  Q6D0D8, APAH_ERWCT ;
DR   B2VGQ8, APAH_ERWT9 ;  B7LVU3, APAH_ESCF3 ;  Q7VLX9, APAH_HAEDU ;
DR   Q4QMZ7, APAH_HAEI8 ;  A5U9U1, APAH_HAEIE ;  A5UH58, APAH_HAEIG ;
DR   P44751, APAH_HAEIN ;  B8F4P0, APAH_HAEPS ;  Q0I5C4, APAH_HAES1 ;
DR   B0URM8, APAH_HAES2 ;  C4K4K8, APAH_HAMD5 ;  A4G8L5, APAH_HERAR ;
DR   A6T287, APAH_JANMA ;  B5Y1Z6, APAH_KLEP3 ;  A6T4I5, APAH_KLEP7 ;
DR   Q5X0V3, APAH_LEGPA ;  A5IIB8, APAH_LEGPC ;  Q5ZRF6, APAH_LEGPH ;
DR   Q5WSM5, APAH_LEGPL ;  Q65UX2, APAH_MANSM ;  A6VU51, APAH_MARMS ;
DR   Q60CE9, APAH_METCA ;  Q1H450, APAH_METFK ;  Q5FA03, APAH_NEIG1 ;
DR   B4RJQ3, APAH_NEIG2 ;  Q9JVF4, APAH_NEIMA ;  Q82WQ0, APAH_NITEU ;
DR   Q2YCK7, APAH_NITMU ;  Q3JBF6, APAH_NITOC ;  P57922, APAH_PASMU ;
DR   C6DEY8, APAH_PECCP ;  Q7N8V9, APAH_PHOLL ;  Q6LV43, APAH_PHOPR ;
DR   B4F2I4, APAH_PROMH ;  Q48NT9, APAH_PSE14 ;  A6UZ94, APAH_PSEA7 ;
DR   B7V4H6, APAH_PSEA8 ;  Q02TH3, APAH_PSEAB ;  Q9I5U7, APAH_PSEAE ;
DR   Q1IG22, APAH_PSEE4 ;  Q4K4X3, APAH_PSEF5 ;  C3K329, APAH_PSEFS ;
DR   A4XZJ6, APAH_PSEMY ;  A5VXJ3, APAH_PSEP1 ;  Q3K5T0, APAH_PSEPF ;
DR   B0KJ91, APAH_PSEPG ;  Q88QT8, APAH_PSEPK ;  B1JE09, APAH_PSEPW ;
DR   Q88A48, APAH_PSESM ;  Q4ZMG3, APAH_PSEU2 ;  A4VHH8, APAH_PSEU5 ;
DR   A1STS0, APAH_PSYIN ;  Q8Y1K9, APAH_RALSO ;  Q21MT2, APAH_SACD2 ;
DR   B5F769, APAH_SALA4 ;  A9MQG4, APAH_SALAR ;  Q57TH2, APAH_SALCH ;
DR   B5FI32, APAH_SALDC ;  B5R1S6, APAH_SALEP ;  B5RGC0, APAH_SALG2 ;
DR   B4TJ45, APAH_SALHS ;  B4T6L4, APAH_SALNS ;  Q5PDE1, APAH_SALPA ;
DR   A9MYM2, APAH_SALPB ;  C0Q5E5, APAH_SALPC ;  B5BL25, APAH_SALPK ;
DR   B4TWT4, APAH_SALSV ;  P0A1B2, APAH_SALTI ;  P0A1B1, APAH_SALTY ;
DR   A8G9N8, APAH_SERP5 ;  B8EB37, APAH_SHEB2 ;  A3D186, APAH_SHEB5 ;
DR   A6WK57, APAH_SHEB8 ;  A9L436, APAH_SHEB9 ;  Q07YJ6, APAH_SHEFN ;
DR   A3QBA1, APAH_SHELP ;  Q8EB91, APAH_SHEON ;  A4Y433, APAH_SHEPC ;
DR   A0L066, APAH_SHESA ;  A8FRV0, APAH_SHESH ;  Q0HLT4, APAH_SHESM ;
DR   Q0HS04, APAH_SHESR ;  A1RMV0, APAH_SHESW ;  B2U257, APAH_SHIB3 ;
DR   Q326I4, APAH_SHIBS ;  Q32K45, APAH_SHIDS ;  Q0T8E6, APAH_SHIF8 ;
DR   Q83SQ2, APAH_SHIFL ;  Q3Z5W0, APAH_SHISS ;  Q2NVX8, APAH_SODGM ;
DR   C5BPC0, APAH_TERTT ;  Q3SMC6, APAH_THIDA ;  B8GMY8, APAH_THISH ;
DR   C4L9L6, APAH_TOLAT ;  A5F8N0, APAH_VIBC3 ;  Q9KUS4, APAH_VIBCH ;
DR   C3LRH2, APAH_VIBCM ;  Q5E866, APAH_VIBF1 ;  B5FGG4, APAH_VIBFM ;
DR   A7N0G6, APAH_VIBHB ;  Q87ST8, APAH_VIBPA ;  Q8DED0, APAH_VIBVU ;
DR   Q7MP88, APAH_VIBVY ;  Q8D3I0, APAH_WIGBR ;  Q8PP27, APAH_XANAC ;
DR   Q3BX84, APAH_XANC5 ;  Q8PCE5, APAH_XANCP ;  Q2NZI2, APAH_XANOM ;
DR   B2SPT1, APAH_XANOP ;  Q5GWB7, APAH_XANOR ;  B2I5R6, APAH_XYLF2 ;
DR   Q9PBJ4, APAH_XYLFA ;  Q87C83, APAH_XYLFT ;  A1JJF2, APAH_YERE8 ;
DR   A7FMC3, APAH_YERP3 ;  Q1C0H7, APAH_YERPA ;  B2K485, APAH_YERPB ;
DR   Q8ZIK7, APAH_YERPE ;  A9QZZ2, APAH_YERPG ;  Q1CMT4, APAH_YERPN ;
DR   A4TQE0, APAH_YERPP ;  Q66ER0, APAH_YERPS ;  B1JKY5, APAH_YERPY ;
//
ID   3.6.1.42
DE   Guanosine-diphosphatase.
AN   GDPase.
CA   GDP + H(2)O = GMP + phosphate.
CC   -!- Also acts on UDP but not on other nucleoside diphosphates and
CC       triphosphates.
PR   PROSITE; PDOC00952;
DR   D2GZV9, ENTP5_AILME;  E1BPW0, ENTP5_BOVIN;  E1C1L6, ENTP5_CHICK;
DR   O75356, ENTP5_HUMAN;  Q9QYC8, ENTP5_MESAU;  Q9WUZ9, ENTP5_MOUSE;
DR   Q6P6S9, ENTP5_RAT  ;  Q8TGG8, GDA1_ASPFU ;  Q8TGH6, GDA1_CANAL ;
DR   Q9HEM6, GDA1_KLULA ;  Q9UT35, GDA1_SCHPO ;  P32621, GDA1_YEAST ;
//
ID   3.6.1.43
DE   Dolichyldiphosphatase.
CA   Dolichyl diphosphate + H(2)O = dolichyl phosphate + phosphate.
DR   P53223, CAX4_YEAST ;  B0KWE9, DOPP1_CALJA;  B1MTH4, DOPP1_CALMO;
DR   Q86IX2, DOPP1_DICDI;  Q86YN1, DOPP1_HUMAN;  Q9JMF7, DOPP1_MOUSE;
DR   B0CM95, DOPP1_PAPAN;  B2KI79, DOPP1_RHIFE;  Q9C2M6, DOPP_NEUCR ;
DR   O59747, PDF1_SCHPO ;
//
ID   3.6.1.44
DE   Oligosaccharide-diphosphodolichol diphosphatase.
AN   Oligosaccharide-diphosphodolichol pyrophosphatase.
CA   Oligosaccharide-diphosphodolichol + H(2)O = oligosaccharide phosphate +
CA   dolichyl phosphate.
//
ID   3.6.1.45
DE   UDP-sugar diphosphatase.
AN   Nucleosidediphosphate-sugar diphosphatase.
AN   Nucleosidediphosphate-sugar pyrophosphatase.
AN   UDP-sugar hydrolase.
AN   UDP-sugar pyrophosphatase.
CA   UDP-sugar + H(2)O = UMP + alpha-D-aldose 1-phosphate.
CF   Divalent cation.
CC   -!- UDP-sugar is the best substrate, although other nucleoside-sugar
CC       diphosphates are used as substrates with similar Km values but much
CC       lower maximum velocities.
CC   -!- Thus, this enzyme has a specificity distinct from that of
CC       EC 3.6.1.21.
CC   -!- Some but not all enzymes of this class also appear to have EC 3.1.3.5
CC       activity.
PR   PROSITE; PDOC00627;
DR   P52307, 5NTD_BOOMI ;  Q9XZ43, 5NTD_LUTLO ;  Q05B60, NUD14_BOVIN;
DR   O95848, NUD14_HUMAN;  Q9D142, NUD14_MOUSE;  P07024, USHA_ECOLI ;
DR   Q9RN37, USHA_SALPU ;  Q56878, USHA_YERE8 ;
//
ID   3.6.1.46
DE   Transferred entry: 3.6.5.1.
//
ID   3.6.1.47
DE   Transferred entry: 3.6.5.2.
//
ID   3.6.1.48
DE   Transferred entry: 3.6.5.3.
//
ID   3.6.1.49
DE   Transferred entry: 3.6.5.4.
//
ID   3.6.1.50
DE   Transferred entry: 3.6.5.5.
//
ID   3.6.1.51
DE   Transferred entry: 3.6.5.6.
//
ID   3.6.1.52
DE   Diphosphoinositol-polyphosphate diphosphatase.
AN   Diphosphoinositol-polyphosphate phosphohydrolase.
AN   DIPP.
CA   Diphospho-myo-inositol polyphosphate + H(2)O = myo-inositol polyphosphate
CA   + phosphate.
CC   -!- This enzyme hydrolyzes the diphosphate bond, leaving a phospho group
CC       where a diphospho group had been.
CC   -!- It can also act on bis(adenosine) diphosphate.
PR   PROSITE; PDOC00695;
DR   Q09790, APS1_SCHPO ;  Q99321, DDP1_YEAST ;  P32092, DIPP_ASFB7 ;
DR   P0C998, DIPP_ASFK5 ;  Q65217, DIPP_ASFM2 ;  P0C996, DIPP_ASFP4 ;
DR   P0C997, DIPP_ASFWA ;  Q5UQW2, DIPP_MIMIV ;  Q8NFP7, NUD10_HUMAN;
DR   P0C027, NUD10_MOUSE;  Q58CW0, NUD11_BOVIN;  Q96G61, NUD11_HUMAN;
DR   P0C028, NUD11_MOUSE;  A2VE79, NUDT3_BOVIN;  O95989, NUDT3_HUMAN;
DR   Q9JI46, NUDT3_MOUSE;  Q566C7, NUDT3_RAT  ;  Q9NZJ9, NUDT4_HUMAN;
DR   Q8R2U6, NUDT4_MOUSE;  Q5RAF0, NUDT4_PONAB;  Q99MY2, NUDT4_RAT  ;
//
ID   3.6.1.53
DE   Mn(2+)-dependent ADP-ribose/CDP-alcohol diphosphatase.
AN   ADPRibase-Mn.
AN   Mn(2+)-dependent ADP-ribose/CDP-alcohol pyrophosphatase.
CA   (1) CDP-choline + H(2)O = CMP + phosphocholine.
CA   (2) ADP-ribose + H(2)O = AMP + D-ribose 5-phosphate.
CF   Manganese.
CC   -!- ADP-ribose, CDP-choline, CDP-ethanolamine and ADP are substrates for
CC       this enzyme but ADP-glucose, UDP-glucose, CDP-glucose, CDP, CMP and
CC       AMP are not hydrolyzed.
DR   A7YY53, ADPRM_BOVIN;  Q7T291, ADPRM_DANRE;  Q3LIE5, ADPRM_HUMAN;
DR   Q99KS6, ADPRM_MOUSE;  Q5M886, ADPRM_RAT  ;  Q7T0Q0, ADPRM_XENLA;
DR   Q66JJ3, ADPRM_XENTR;
//
ID   3.6.1.54
DE   UDP-2,3-diacylglucosamine diphosphatase.
AN   UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine diphosphatase.
AN   UDP-2,3-diacylglucosamine hydrolase.
AN   UDP-2,3-diacylglucosamine pyrophosphatase.
CA   UDP-2,3-bis((3R)-3-hydroxymyristoyl)-alpha-D-glucosamine + H(2)O = 2,3-
CA   bis((3R)-3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate + UMP.
CC   -!- The enzyme catalyzes a step in the biosynthesis of lipid A.
CC   -!- Formerly EC 3.6.1.n5.
//
ID   3.6.1.n1
DE   D-tyrosyl-tRNA(Tyr) hydrolase.
AN   D-tyrosyl-tRNA(Tyr) deacylase.
AN   DTD.
CA   D-tyrosyl-tRNA(Tyr) + H(2)O = tRNA(Tyr) + D-tyrosine.
//
ID   3.6.1.n2
DE   L-cysteinyl-tRNA(Pro).
AN   Cys-tRNA(Pro) deacylase.
CA   L-cysteinyl-tRNA(Pro) + H(2)O = tRNA(Pro) + L-cysteine.
CC   -!- The enzyme from Escherichia coli also catalyzes the reaction of
CC       EC 3.6.1.n3.
//
ID   3.6.1.n3
DE   L-cysteinyl-tRNA(Cys) hydrolase.
AN   Cys-tRNA(Cys) deacylase.
CA   L-cysteinyl-tRNA(Cys) + H(2)O = tRNA(Cys) + L-cysteine.
CC   -!- The enzyme from Escherichia coli also catalyzes the reaction of
CC       EC 3.6.1.n2.
//
ID   3.6.1.n4
DE   Dihydroneopterin triphosphate diphosphatase.
AN   Dihydroneopterin triphosphate pyrophosphatase.
CA   7,8-dihydroneopterin 3'-triphosphate + H(2)O = 7,8-dihydroneopterin
CA   3'-phosphate + diphosphate.
CF   Magnesium.
CC   -!- Part of the folate biosynthesis pathway in bacteria, together with
CC       EC 4.1.2.25, EC 2.7.6.3, EC 2.5.1.15 and EC 6.3.2.12.
CC   -!- Member of the NUDIX family of diphosphatases.
//
ID   3.6.1.n5
DE   Transferred entry: 3.6.1.54.
//
ID   3.6.2.1
DE   Adenylylsulfatase.
CA   Adenylyl sulfate + H(2)O = AMP + sulfate.
//
ID   3.6.2.2
DE   Phosphoadenylylsulfatase.
AN   3-phosphoadenylyl sulfatase.
AN   PAPS sulfatase.
CA   3'-phosphoadenylyl sulfate + H(2)O = adenosine 3',5'-bisphosphate +
CA   sulfate.
CF   Manganese.
//
ID   3.6.3.1
DE   Phospholipid-translocating ATPase.
AN   Flippase.
AN   Magnesium-ATPase.
AN   Mg(2+)-ATPase.
AN   Phospholipid-transporting ATPase.
CA   ATP + H(2)O + phospholipid(In) = ADP + phosphate + phospholipid(Out).
CF   Magnesium.
CC   -!- P-type ATPase that undergoes covalent phosphorylation during the
CC       transport cycle.
CC   -!- The enzyme apparently has several activities, one of them being the
CC       movement of phospholipids from one membrane face to the other.
CC   -!- Formerly EC 3.6.3.13.
PR   PROSITE; PDOC00139;
DR   Q9LI83, ALA10_ARATH;  Q9SAF5, ALA11_ARATH;  P57792, ALA12_ARATH;
DR   P98204, ALA1_ARATH ;  P98205, ALA2_ARATH ;  Q9XIE6, ALA3_ARATH ;
DR   Q9LNQ4, ALA4_ARATH ;  Q9SGG3, ALA5_ARATH ;  Q9SLK6, ALA6_ARATH ;
DR   Q9LVK9, ALA7_ARATH ;  Q9LK90, ALA8_ARATH ;  Q9SX33, ALA9_ARATH ;
DR   O60312, AT10A_HUMAN;  O54827, AT10A_MOUSE;  O94823, AT10B_HUMAN;
DR   Q9P241, AT10D_HUMAN;  Q9GKS6, AT10D_MACFA;  Q8K2X1, AT10D_MOUSE;
DR   P98196, AT11A_HUMAN;  P98197, AT11A_MOUSE;  Q9Y2G3, AT11B_HUMAN;
DR   Q9N0Z4, AT11B_RABIT;  Q8NB49, AT11C_HUMAN;  Q9QZW0, AT11C_MOUSE;
DR   Q29449, AT8A1_BOVIN;  Q9Y2Q0, AT8A1_HUMAN;  P70704, AT8A1_MOUSE;
DR   Q9NTI2, AT8A2_HUMAN;  P98200, AT8A2_MOUSE;  O43520, AT8B1_HUMAN;
DR   Q148W0, AT8B1_MOUSE;  Q5BL50, AT8B1_XENTR;  P98198, AT8B2_HUMAN;
DR   P98199, AT8B2_MOUSE;  O60423, AT8B3_HUMAN;  Q8TF62, AT8B4_HUMAN;
DR   A3FIN4, AT8B5_MOUSE;  P39524, ATC3_YEAST ;  Q12675, ATC4_YEAST ;
DR   P32660, ATC5_YEAST ;  P40527, ATC7_YEAST ;  Q12674, ATC8_YEAST ;
DR   Q09891, ATCX_SCHPO ;  O36028, ATCZ_SCHPO ;  O75110, ATP9A_HUMAN;
DR   O70228, ATP9A_MOUSE;  A1A4J6, ATP9B_BOVIN;  O43861, ATP9B_HUMAN;
DR   P98195, ATP9B_MOUSE;  Q10309, YD56_SCHPO ;  Q9UT43, YFRD_SCHPO ;
DR   O94296, YOOC_SCHPO ;
//
ID   3.6.3.2
DE   Magnesium-importing ATPase.
AN   Magnesium-translocating P-type ATPase.
AN   Mg(2+)-importing ATPase.
CA   ATP + H(2)O + Mg(2+)(Out) = ADP + phosphate + Mg(2+)(In).
CF   Magnesium.
CC   -!- P-type ATPase that undergoes covalent phosphorylation during the
CC       transport cycle.
PR   PROSITE; PDOC00139;
DR   P0ABB9, ATMA_ECO57 ;  P0ABB8, ATMA_ECOLI ;  D0ZTB2, ATMA_SALT1 ;
DR   P36640, ATMA_SALTY ;  P22036, ATMB_SALTY ;
//
ID   3.6.3.3
DE   Cadmium-exporting ATPase.
AN   Cadmium-translocating P-type ATPase.
AN   Cd(2+)-exporting ATPase.
CA   ATP + H(2)O + Cd(2+)(In) = ADP + phosphate + Cd(2+)(Out).
CF   Magnesium.
CC   -!- P-type ATPase that undergoes covalent phosphorylation during the
CC       transport cycle.
PR   PROSITE; PDOC00139;
DR   Q9M3H5, AHM1_ARATH ;  O64474, AHM2_ARATH ;  Q9SZW4, AHM3_ARATH ;
DR   P0CW78, AHM4B_ARATH;  P38360, ATU1_YEAST ;  P37617, ATZN_ECOLI ;
DR   P58414, CADA1_LISMO;  P20021, CADA1_STAAU;  Q60048, CADA2_LISMO;
DR   P37386, CADA2_STAAU;  P30336, CADA_BACPE ;  O32219, CADA_BACSU ;
DR   Q6GIX1, CADA_STAAR ;  Q9RQB4, HMCT_HELFE ;  Q9ZL53, HMCT_HELPJ ;
DR   Q59465, HMCT_HELPY ;
//
ID   3.6.3.4
DE   Copper-exporting ATPase.
AN   Copper-translocating P-type ATPase.
AN   Copper-transporting ATPase.
AN   Cu(2+)-exporting ATPase.
CA   ATP + H(2)O + Cu(2+)(In) = ADP + phosphate + Cu(2+)(Out).
CF   Magnesium.
CC   -!- P-type ATPase that undergoes covalent phosphorylation during the
CC       transport cycle.
PR   PROSITE; PDOC00139;
DR   Q9S7J8, AHM5_ARATH ;  Q9SZC9, AHM6_ARATH ;  Q9SH30, AHM7_ARATH ;
DR   P58341, ATCU1_RHIME;  P58342, ATCU2_RHIME;  Q9X5V3, ATCU_RHILV ;
DR   Q9X5X3, ATCU_SINMW ;  P49015, ATP7A_CRIGR;  Q04656, ATP7A_HUMAN;
DR   Q64430, ATP7A_MOUSE;  P70705, ATP7A_RAT  ;  P35670, ATP7B_HUMAN;
DR   Q64446, ATP7B_MOUSE;  Q64535, ATP7B_RAT  ;  Q9XT50, ATP7B_SHEEP;
DR   P37385, ATSY_SYNE7 ;  P07893, ATSY_SYNP6 ;  O59666, ATU2_SCHPO ;
DR   P38995, ATU2_YEAST ;  P77871, COPA1_HELPY;  Q59467, COPA2_HELPY;
DR   O08462, COPA3_HELPY;  O32619, COPA_HELFC ;  Q9ZM69, COPA_HELPJ ;
DR   P55989, COPA_HELPY ;  O30085, COPB_ARCFU ;
//
ID   3.6.3.5
DE   Zinc-exporting ATPase.
AN   P(1B)-type ATPase.
AN   Zinc-translocating P-type ATPase.
AN   Zn(2+)-exporting ATPase.
CA   ATP + H(2)O + Zn(2+)(In) = ADP + phosphate + Zn(2+)(Out).
CF   Magnesium.
CC   -!- P-type ATPase that undergoes covalent phosphorylation during the
CC       transport cycle.
CC   -!- This enzyme also exports Cd(2+) and Co(2+).
PR   PROSITE; PDOC00139;
DR   Q9M3H5, AHM1_ARATH ;  O64474, AHM2_ARATH ;  Q9SZW4, AHM3_ARATH ;
DR   P0CW78, AHM4B_ARATH;  P37617, ATZN_ECOLI ;  Q59998, ATZN_SYNY3 ;
DR   O32219, CADA_BACSU ;  Q9RQB4, HMCT_HELFE ;  Q9ZL53, HMCT_HELPJ ;
DR   Q59465, HMCT_HELPY ;  O31688, ZOSA_BACSU ;
//
ID   3.6.3.6
DE   Proton-exporting ATPase.
AN   H(+)-exporting ATPase.
AN   H(+)-transporting ATPase.
AN   Proton transport ATPase.
AN   Proton-translocating P-type ATPase.
CA   ATP + H(2)O + H(+)(In) = ADP + phosphate + H(+)(Out).
CF   Magnesium.
CC   -!- P-type ATPase that undergoes covalent phosphorylation during the
CC       transport cycle.
CC   -!- Generates an electrochemical potential gradient of protons across the
CC       plasma membrane.
CC   -!- Formerly EC 3.6.1.35.
PR   PROSITE; PDOC00139;
DR   P11718, ATXA_LEIDO ;  P12522, ATXB_LEIDO ;  Q43128, PMA10_ARATH;
DR   Q9LV11, PMA11_ARATH;  Q07421, PMA1_AJECA ;  P20649, PMA1_ARATH ;
DR   P28877, PMA1_CANAL ;  P54679, PMA1_DICDI ;  P54210, PMA1_DUNAC ;
DR   P54211, PMA1_DUNBI ;  P49380, PMA1_KLULA ;  P07038, PMA1_NEUCR ;
DR   Q08435, PMA1_NICPL ;  Q7XPY2, PMA1_ORYSJ ;  P09627, PMA1_SCHPO ;
DR   P22180, PMA1_SOLLC ;  P83970, PMA1_WHEAT ;  P05030, PMA1_YEAST ;
DR   P24545, PMA1_ZYGRO ;  P19456, PMA2_ARATH ;  P28876, PMA2_SCHPO ;
DR   P23980, PMA2_SOLLC ;  P19657, PMA2_YEAST ;  P20431, PMA3_ARATH ;
DR   Q08436, PMA3_NICPL ;  Q9SU58, PMA4_ARATH ;  Q03194, PMA4_NICPL ;
DR   Q9SJB3, PMA5_ARATH ;  Q9SH76, PMA6_ARATH ;  Q9LY32, PMA7_ARATH ;
DR   Q9M2A0, PMA8_ARATH ;  Q42556, PMA9_ARATH ;  Q7M290, PMA_AVESA  ;
//
ID   3.6.3.7
DE   Sodium-exporting ATPase.
AN   Na(+)-exporting ATPase.
AN   Na(+)-transporting ATPase.
AN   Sodium transport ATPase.
AN   Sodium-translocating P-type ATPase.
CA   ATP + H(2)O + Na(+)(In) = ADP + phosphate + Na(+)(Out).
CF   Magnesium.
CC   -!- P-type ATPase that undergoes covalent phosphorylation during the
CC       transport cycle.
CC   -!- Involved in the efflux of Na(+), with one ion being exported per ATP
CC       hydrolyzed.
PR   PROSITE; PDOC00139;
DR   P13587, ATN1_YEAST ;  Q01896, ATN2_YEAST ;  Q12691, ATN5_YEAST ;
//
ID   3.6.3.8
DE   Calcium-transporting ATPase.
AN   Ca(2+)-transporting ATPase.
AN   Calcium pump.
AN   Calcium-translocating P-type ATPase.
CA   ATP + H(2)O + Ca(2+)(Cis) = ADP + phosphate + Ca(2+)(Trans).
CF   Magnesium.
CC   -!- P-type ATPase that undergoes covalent phosphorylation during the
CC       transport cycle.
CC   -!- This enzyme family comprises three types of Ca(2+)-transporting
CC       enzymes that are found in the plasma membrane, the sarcoplasmic
CC       reticulum and in Saccharomyces cerevisiae.
CC   -!- The first and third transport one ion per ATP hydrolyzed, whereas the
CC       second transports two ions.
CC   -!- Formerly EC 3.6.1.38.
PR   PROSITE; PDOC00139;
DR   Q9SZR1, ACA10_ARATH;  Q9M2L4, ACA11_ARATH;  Q9LY77, ACA12_ARATH;
DR   Q9LIK7, ACA13_ARATH;  Q37145, ACA1_ARATH ;  Q2QMX9, ACA1_ORYSJ ;
DR   O81108, ACA2_ARATH ;  Q6ATV4, ACA2_ORYSJ ;  Q8RUN1, ACA3_ORYSJ ;
DR   O22218, ACA4_ARATH ;  Q2QY12, ACA4_ORYSJ ;  Q2RAS0, ACA5_ORYSJ ;
DR   Q65X71, ACA6_ORYSJ ;  O64806, ACA7_ARATH ;  Q9LF79, ACA8_ARATH ;
DR   Q9LU41, ACA9_ARATH ;  Q0VCY0, AT2A1_BOVIN;  P13585, AT2A1_CHICK;
DR   O14983, AT2A1_HUMAN;  P70083, AT2A1_MAKNI;  Q8R429, AT2A1_MOUSE;
DR   P04191, AT2A1_RABIT;  Q92105, AT2A1_RANES;  Q64578, AT2A1_RAT  ;
DR   O46674, AT2A2_CANFA;  Q03669, AT2A2_CHICK;  Q00779, AT2A2_FELCA;
DR   P16615, AT2A2_HUMAN;  O55143, AT2A2_MOUSE;  P11607, AT2A2_PIG  ;
DR   P20647, AT2A2_RABIT;  P11507, AT2A2_RAT  ;  Q9YGL9, AT2A3_CHICK;
DR   Q93084, AT2A3_HUMAN;  Q64518, AT2A3_MOUSE;  O77696, AT2A3_PIG  ;
DR   P18596, AT2A3_RAT  ;  P86911, AT2A_CHIOP ;  Q98SH2, AT2B1_CHICK;
DR   P20020, AT2B1_HUMAN;  P23220, AT2B1_PIG  ;  Q00804, AT2B1_RABIT;
DR   P11505, AT2B1_RAT  ;  Q01814, AT2B2_HUMAN;  Q9R0K7, AT2B2_MOUSE;
DR   P58165, AT2B2_OREMO;  P11506, AT2B2_RAT  ;  Q16720, AT2B3_HUMAN;
DR   Q64568, AT2B3_RAT  ;  P23634, AT2B4_HUMAN;  Q64542, AT2B4_RAT  ;
DR   P57709, AT2C1_BOVIN;  P98194, AT2C1_HUMAN;  Q80XR2, AT2C1_MOUSE;
DR   Q5R5K5, AT2C1_PONAB;  Q64566, AT2C1_RAT  ;  O75185, AT2C2_HUMAN;
DR   A7L9Z8, AT2C2_MOUSE;  Q8R4C1, AT2C2_RAT  ;  Q7PPA5, ATC1_ANOGA ;
DR   P54678, ATC1_DICDI ;  P22700, ATC1_DROME ;  Q292Q0, ATC1_DROPS ;
DR   O59868, ATC1_SCHPO ;  O43108, ATC1_YARLI ;  P13586, ATC1_YEAST ;
DR   Q9HDW7, ATC2_SCHPO ;  P38929, ATC2_YEAST ;  P22189, ATC3_SCHPO ;
DR   O34431, ATCL_BACSU ;  P37278, ATCL_SYNE7 ;  P35316, ATC_ARTSF  ;
DR   Q08853, ATC_PLAFK  ;  P35315, ATC_TRYBB  ;  P92939, ECA1_ARATH ;
DR   O23087, ECA2_ARATH ;  Q9SY55, ECA3_ARATH ;  Q9XES1, ECA4_ARATH ;
DR   Q42883, ECAP_SOLLC ;  Q8Y8Q5, LMCA1_LISMO;
//
ID   3.6.3.9
DE   Sodium/potassium-exchanging ATPase.
AN   Na(+)/K(+)-ATPase.
AN   Na(+)/K(+)-exchanging ATPase.
AN   Na,K-activated ATPase.
AN   Sodium pump.
AN   Sodium/potassium-transporting ATPase.
CA   ATP + H(2)O + Na(+)(In) + K(+)(Out) = ADP + phosphate + Na(+)(Out) +
CA   K(+)(In).
CF   Magnesium.
CC   -!- P-type ATPase that undergoes covalent phosphorylation during the
CC       transport cycle.
CC   -!- An enzyme from the plasma membrane of animal cells that catalyzes the
CC       efflux of three Na(+) and influx of two K(+) per ATP hydrolyzed.
CC   -!- It is involved in generating the plasma membrane electrical
CC       potential.
CC   -!- Formerly EC 3.6.1.37.
PR   PROSITE; PDOC00139;
PR   PROSITE; PDOC00328;
DR   Q92030, AT1A1_ANGAN;  Q08DA1, AT1A1_BOVIN;  P30714, AT1A1_BUFMA;
DR   P50997, AT1A1_CANFA;  P25489, AT1A1_CATCO;  P09572, AT1A1_CHICK;
DR   P18907, AT1A1_HORSE;  P05023, AT1A1_HUMAN;  Q8VDN2, AT1A1_MOUSE;
DR   Q9YH26, AT1A1_OREMO;  P05024, AT1A1_PIG  ;  Q5RDR3, AT1A1_PONAB;
DR   Q9N0Z6, AT1A1_RABIT;  P06685, AT1A1_RAT  ;  P04074, AT1A1_SHEEP;
DR   Q92123, AT1A1_XENLA;  A2VDL6, AT1A2_BOVIN;  P24797, AT1A2_CHICK;
DR   P50993, AT1A2_HUMAN;  Q6PIE5, AT1A2_MOUSE;  D2WKD8, AT1A2_PIG  ;
DR   Q5RCD8, AT1A2_PONAB;  P06686, AT1A2_RAT  ;  P24798, AT1A3_CHICK;
DR   P13637, AT1A3_HUMAN;  Q6PIC6, AT1A3_MOUSE;  P58312, AT1A3_OREMO;
DR   P06687, AT1A3_RAT  ;  Q13733, AT1A4_HUMAN;  Q9WV27, AT1A4_MOUSE;
DR   Q64541, AT1A4_RAT  ;  P17326, AT1A_ARTSF ;  P35317, AT1A_HYDVU ;
DR   Q6RWA9, AT1A_TAESO ;  P05025, AT1A_TORCA ;  P28774, AT1B_ARTSF ;
DR   P13607, ATNA_DROME ;
//
ID   3.6.3.10
DE   Hydrogen/potassium-exchanging ATPase.
AN   Gastric H(+)/K(+) ATPase.
AN   H(+)/K(+)-ATPase.
AN   H(+)/K(+)-exchanging ATPase.
AN   Potassium-transporting ATPase.
AN   Proton pump.
CA   ATP + H(2)O + H(+)(In) + K(+)(Out) = ADP + phosphate + H(+)(Out) +
CA   K(+)(In).
CF   Magnesium.
CC   -!- P-type ATPase that undergoes covalent phosphorylation during the
CC       transport cycle.
CC   -!- Hydrolysis of ATP is coupled with the exchange of H(+) and K(+) ions.
CC   -!- Formerly EC 3.6.1.36.
PR   PROSITE; PDOC00139;
DR   Q92036, AT12A_BUFMA;  Q64392, AT12A_CAVPO;  P54707, AT12A_HUMAN;
DR   Q9Z1W8, AT12A_MOUSE;  Q9TV52, AT12A_RABIT;  P54708, AT12A_RAT  ;
DR   P50996, ATP4A_CANFA;  P20648, ATP4A_HUMAN;  Q64436, ATP4A_MOUSE;
DR   P19156, ATP4A_PIG  ;  P27112, ATP4A_RABIT;  P09626, ATP4A_RAT  ;
DR   Q92126, ATP4A_XENLA;
//
ID   3.6.3.11
DE   Chloride-transporting ATPase.
AN   Chloride-motive ATPase.
AN   Chloride-translocating ATPase.
AN   Cl(-)-transporting ATPase.
CA   ATP + H(2)O + Cl(-)(Out) = ADP + phosphate + Cl(-)(In).
CF   Magnesium.
CC   -!- P-type ATPase that undergoes covalent phosphorylation during the
CC       transport cycle.
PR   PROSITE; PDOC00139;
//
ID   3.6.3.12
DE   Potassium-transporting ATPase.
AN   K(+)-importing ATPase.
AN   K(+)-transporting ATPase.
AN   Potassium-importing ATPase.
CA   ATP + H(2)O + K(+)(Out) = ADP + phosphate + K(+)(In).
CF   Magnesium.
CC   -!- P-type ATPase that undergoes covalent phosphorylation during the
CC       transport cycle.
CC   -!- A bacterial enzyme of di(heterotetrameric) structure that is involved
CC       in K(+) import.
CC   -!- The probable stoichiometry is one ion per ATP hydrolyzed.
PR   PROSITE; PDOC00139;
DR   Q99SH9, ATKA1_STAAM;  Q7A4G4, ATKA1_STAAN;  Q6GEZ6, ATKA1_STAAR;
DR   P0A056, ATKA2_STAAM;  P0A057, ATKA2_STAAN;  Q6GKN4, ATKA2_STAAR;
DR   P0A058, ATKA2_STAAU;  A1TJ24, ATKA_ACIAC ;  Q1IUD5, ATKA_ACIBL ;
DR   C1FA47, ATKA_ACIC5 ;  B9JKQ7, ATKA_AGRRK ;  Q8U9D8, ATKA_AGRT5 ;
DR   B9K2I3, ATKA_AGRVS ;  Q9XE11, ATKA_ALIAD ;  Q2IPD5, ATKA_ANADE ;
DR   Q9R6X2, ATKA_ANASL ;  C3P0L9, ATKA_BACAA ;  C3LFA0, ATKA_BACAC ;
DR   A0RA12, ATKA_BACAH ;  Q81UW7, ATKA_BACAN ;  B7JRB7, ATKA_BACC0 ;
DR   Q73DA4, ATKA_BACC1 ;  B7II08, ATKA_BACC2 ;  C1EYJ9, ATKA_BACC3 ;
DR   B7HDF8, ATKA_BACC4 ;  B7HWG0, ATKA_BACC7 ;  B9J529, ATKA_BACCQ ;
DR   Q81HQ1, ATKA_BACCR ;  Q63FR1, ATKA_BACCZ ;  Q5LHU7, ATKA_BACFN ;
DR   Q64YU9, ATKA_BACFR ;  Q6HN79, ATKA_BACHK ;  Q8A519, ATKA_BACTN ;
DR   A6L5D2, ATKA_BACV8 ;  A9VFM0, ATKA_BACWK ;  B2IIP5, ATKA_BEII9 ;
DR   Q2KWC8, ATKA_BORA1 ;  Q7WCL8, ATKA_BORBR ;  Q7W536, ATKA_BORPA ;
DR   Q7VVZ9, ATKA_BORPE ;  Q89FC2, ATKA_BRAJA ;  Q62IJ6, ATKA_BURMA ;
DR   Q63VS3, ATKA_BURPS ;  B8GVF8, ATKA_CAUCN ;  Q9A7X8, ATKA_CAUCR ;
DR   B0SYJ7, ATKA_CAUSK ;  Q7NXM7, ATKA_CHRVO ;  A8AJB7, ATKA_CITK8 ;
DR   A5CUP8, ATKA_CLAM3 ;  B0RCI3, ATKA_CLAMS ;  O32327, ATKA_CLOAB ;
DR   B2V2P2, ATKA_CLOBA ;  B2TMJ1, ATKA_CLOBB ;  Q0TRT4, ATKA_CLOP1 ;
DR   B7JY03, ATKA_CYAP8 ;  Q47H38, ATKA_DECAR ;  Q9RZN7, ATKA_DEIRA ;
DR   A9C190, ATKA_DELAS ;  B8J1E9, ATKA_DESDA ;  C4XKM8, ATKA_DESMR ;
DR   Q725T6, ATKA_DESVH ;  A1V9G1, ATKA_DESVV ;  A7ZJ81, ATKA_ECO24 ;
DR   B7UKX7, ATKA_ECO27 ;  B7MFW3, ATKA_ECO45 ;  B7LAA5, ATKA_ECO55 ;
DR   Q8X9F8, ATKA_ECO57 ;  B5YQP0, ATKA_ECO5E ;  B7NMQ1, ATKA_ECO7I ;
DR   B7MPK1, ATKA_ECO81 ;  B7M5L4, ATKA_ECO8A ;  C4ZWH4, ATKA_ECOBW ;
DR   B1X6M9, ATKA_ECODH ;  A7ZXV9, ATKA_ECOHS ;  Q0TJY8, ATKA_ECOL5 ;
DR   Q8FJV3, ATKA_ECOL6 ;  B1IY31, ATKA_ECOLC ;  P03959, ATKA_ECOLI ;
DR   B7N9U1, ATKA_ECOLU ;  B6HYQ6, ATKA_ECOSE ;  B1LLE2, ATKA_ECOSM ;
DR   Q1REL9, ATKA_ECOUT ;  C5BG86, ATKA_EDWI9 ;  A4W861, ATKA_ENT38 ;
DR   A7MQU8, ATKA_ENTS8 ;  Q6D7I3, ATKA_ERWCT ;  B2VJK4, ATKA_ERWT9 ;
DR   B7LKR6, ATKA_ESCF3 ;  A5FIF9, ATKA_FLAJ1 ;  A6H086, ATKA_FLAPJ ;
DR   Q0RF16, ATKA_FRAAA ;  B0TWK0, ATKA_FRAP2 ;  A7NER4, ATKA_FRATF ;
DR   Q2A1A6, ATKA_FRATH ;  B2SEB4, ATKA_FRATM ;  A0Q8L0, ATKA_FRATN ;
DR   Q0BK20, ATKA_FRATO ;  A4IVV7, ATKA_FRATW ;  B5EH80, ATKA_GEOBB ;
DR   Q5KUV3, ATKA_GEOKA ;  Q39SW6, ATKA_GEOMG ;  P94456, ATKA_GEOSE ;
DR   Q74AB0, ATKA_GEOSL ;  A5GAG2, ATKA_GEOUR ;  Q7NN41, ATKA_GLOVI ;
DR   Q0BVS2, ATKA_GRABC ;  P57684, ATKA_HALSA ;  A9AXU9, ATKA_HERA2 ;
DR   A4G5J9, ATKA_HERAR ;  B4U8E3, ATKA_HYDS0 ;  A6SZ16, ATKA_JANMA ;
DR   A6W6R5, ATKA_KINRD ;  B5XZE8, ATKA_KLEP3 ;  A6T6D9, ATKA_KLEP7 ;
DR   C1D7X0, ATKA_LARHH ;  Q72TM7, ATKA_LEPIC ;  Q8F1M1, ATKA_LEPIN ;
DR   Q927F9, ATKA_LISIN ;  C1KZN6, ATKA_LISMC ;  Q71W89, ATKA_LISMF ;
DR   B8DAW0, ATKA_LISMH ;  Q8Y3Z6, ATKA_LISMO ;  A0AM17, ATKA_LISW6 ;
DR   Q2W612, ATKA_MAGSA ;  A7I5F0, ATKA_METB6 ;  B7L1M9, ATKA_METC4 ;
DR   Q605R1, ATKA_METCA ;  A9VZA2, ATKA_METEP ;  B3DWK0, ATKA_METI4 ;
DR   B8I9I5, ATKA_METNO ;  B1Z9Y2, ATKA_METPB ;  A2SIS3, ATKA_METPP ;
DR   B1M7D7, ATKA_METRJ ;  B0JJ94, ATKA_MICAN ;  A0QBY3, ATKA_MYCA1 ;
DR   B1MDL1, ATKA_MYCA9 ;  P65210, ATKA_MYCBO ;  A1KHG8, ATKA_MYCBP ;
DR   C1AM21, ATKA_MYCBT ;  Q741T7, ATKA_MYCPA ;  A0R395, ATKA_MYCS2 ;
DR   A3Q5E2, ATKA_MYCSJ ;  A1UKX6, ATKA_MYCSK ;  Q1B453, ATKA_MYCSS ;
DR   A5U173, ATKA_MYCTA ;  P65209, ATKA_MYCTU ;  A1TED2, ATKA_MYCVP ;
DR   Q5YZH9, ATKA_NOCFA ;  Q8YPE8, ATKA_NOSS1 ;  A6X5H8, ATKA_OCHA4 ;
DR   A6LIU6, ATKA_PARD8 ;  C6DCB6, ATKA_PECCP ;  Q7N6W5, ATKA_PHOLL ;
DR   A1VTC2, ATKA_POLNA ;  A4SZG9, ATKA_POLSQ ;  Q6ABJ2, ATKA_PROAC ;
DR   P57683, ATKA_PSEAE ;  Q1I7N9, ATKA_PSEE4 ;  C3K4Y3, ATKA_PSEFS ;
DR   Q3K8Y4, ATKA_PSEPF ;  Q88FD7, ATKA_PSEPK ;  Q883V6, ATKA_PSESM ;
DR   B2UH25, ATKA_RALPJ ;  Q8XU12, ATKA_RALSO ;  Q98GX5, ATKA_RHILO ;
DR   Q92XI9, ATKA_RHIME ;  B6IQY9, ATKA_RHOCS ;  C1A1E9, ATKA_RHOE4 ;
DR   C1AUJ4, ATKA_RHOOB ;  Q6N5H0, ATKA_RHOPA ;  Q2RV89, ATKA_RHORT ;
DR   Q0SHD0, ATKA_RHOSR ;  B5EZE4, ATKA_SALA4 ;  A9MK88, ATKA_SALAR ;
DR   Q57RM9, ATKA_SALCH ;  B5FNE1, ATKA_SALDC ;  B5QWF0, ATKA_SALEP ;
DR   B5R671, ATKA_SALG2 ;  B4TBA7, ATKA_SALHS ;  B4SZB2, ATKA_SALNS ;
DR   Q5PCJ8, ATKA_SALPA ;  A9MUD9, ATKA_SALPB ;  C0PWC8, ATKA_SALPC ;
DR   B5BCA3, ATKA_SALPK ;  B4TQ23, ATKA_SALSV ;  Q8Z8E4, ATKA_SALTI ;
DR   Q8ZQW1, ATKA_SALTY ;  A8GB62, ATKA_SERP5 ;  B2TTJ6, ATKA_SHIB3 ;
DR   Q324K9, ATKA_SHIBS ;  Q83S83, ATKA_SHIFL ;  Q3Z4A5, ATKA_SHISS ;
DR   Q02CX7, ATKA_SOLUE ;  A9F773, ATKA_SORC5 ;  Q2FF48, ATKA_STAA3 ;
DR   Q2FWH9, ATKA_STAA8 ;  Q2YUH6, ATKA_STAAB ;  Q5HEC3, ATKA_STAAC ;
DR   A6QIS2, ATKA_STAAE ;  Q6G7N2, ATKA_STAAS ;  A8Z4Y0, ATKA_STAAT ;
DR   Q8NVI1, ATKA_STAAW ;  Q5HK63, ATKA_STAEQ ;  Q4LAI3, ATKA_STAHJ ;
DR   Q82PI3, ATKA_STRAW ;  Q9X900, ATKA_STRCO ;  B1W3K2, ATKA_STRGG ;
DR   P73866, ATKA_SYNY3 ;  P57685, ATKA_THEAC ;  Q8R8I5, ATKA_THETN ;
DR   Q97BF7, ATKA_THEVO ;  C4LDL6, ATKA_TOLAT ;  C5CPD4, ATKA_VARPS ;
DR   A1JQY4, ATKA_YERE8 ;  A7FFR1, ATKA_YERP3 ;  Q1C585, ATKA_YERPA ;
DR   B2KA77, ATKA_YERPB ;  Q8ZD96, ATKA_YERPE ;  A9R3X4, ATKA_YERPG ;
DR   Q1CKH1, ATKA_YERPN ;  A4TL05, ATKA_YERPP ;  Q667S5, ATKA_YERPS ;
DR   B1JR97, ATKA_YERPY ;  Q927G0, ATKB1_LISIN;  Q8YPE9, ATKB1_NOSS1;
DR   P0A007, ATKB1_STAAM;  P0A008, ATKB1_STAAN;  Q6GKN3, ATKB1_STAAR;
DR   Q926K7, ATKB2_LISIN;  Q8YSD5, ATKB2_NOSS1;  P63683, ATKB2_STAAM;
DR   P63684, ATKB2_STAAN;  Q6GEZ7, ATKB2_STAAR;  Q8U9D9, ATKB_AGRT5 ;
DR   Q9R6X1, ATKB_ANASL ;  C3LF99, ATKB_BACAC ;  A0RA13, ATKB_BACAH ;
DR   B7JRB8, ATKB_BACC0 ;  B7II09, ATKB_BACC2 ;  C1EYK0, ATKB_BACC3 ;
DR   B7HDF9, ATKB_BACC4 ;  B7HWG1, ATKB_BACC7 ;  A7GLG4, ATKB_BACCN ;
DR   Q81HQ0, ATKB_BACCR ;  Q63FR0, ATKB_BACCZ ;  Q6HN78, ATKB_BACHK ;
DR   A9VFM1, ATKB_BACWK ;  Q9A7X7, ATKB_CAUCR ;  O32328, ATKB_CLOAB ;
DR   B2V2P3, ATKB_CLOBA ;  B2TMJ2, ATKB_CLOBB ;  Q0TRT3, ATKB_CLOP1 ;
DR   Q47H39, ATKB_DECAR ;  Q9RZP0, ATKB_DEIRA ;  A7ZJ80, ATKB_ECO24 ;
DR   B7UKX6, ATKB_ECO27 ;  B7MFW2, ATKB_ECO45 ;  B7LAA4, ATKB_ECO55 ;
DR   Q8X9F9, ATKB_ECO57 ;  B5YQN9, ATKB_ECO5E ;  B7NMQ0, ATKB_ECO7I ;
DR   B7MPK0, ATKB_ECO81 ;  B7M5L3, ATKB_ECO8A ;  C4ZWH3, ATKB_ECOBW ;
DR   B1X6M8, ATKB_ECODH ;  A7ZXV8, ATKB_ECOHS ;  A1A8W1, ATKB_ECOK1 ;
DR   Q0TJY9, ATKB_ECOL5 ;  Q8FJV4, ATKB_ECOL6 ;  B1IY32, ATKB_ECOLC ;
DR   P03960, ATKB_ECOLI ;  B7N9U0, ATKB_ECOLU ;  B6HYQ5, ATKB_ECOSE ;
DR   B1LLE1, ATKB_ECOSM ;  Q1REM0, ATKB_ECOUT ;  A4W860, ATKB_ENT38 ;
DR   Q8KU73, ATKB_ENTFA ;  B2VJK3, ATKB_ERWT9 ;  B7LKR7, ATKB_ESCF3 ;
DR   P57699, ATKB_HALSA ;  B4U8E4, ATKB_HYDS0 ;  B5XZE9, ATKB_KLEP3 ;
DR   A6T6D8, ATKB_KLEP7 ;  Q72TM6, ATKB_LEPIC ;  P59219, ATKB_LEPIN ;
DR   C1KZN5, ATKB_LISMC ;  Q71W90, ATKB_LISMF ;  B8DAW1, ATKB_LISMH ;
DR   Q8Y3Z7, ATKB_LISMO ;  A0AM16, ATKB_LISW6 ;  P63682, ATKB_MYCBO ;
DR   P63681, ATKB_MYCTU ;  Q93MV5, ATKB_MYXXA ;  Q7N6W6, ATKB_PHOLL ;
DR   A4SZG8, ATKB_POLSQ ;  P57698, ATKB_PSEAE ;  Q8XU11, ATKB_RALSO ;
DR   Q98GX6, ATKB_RHILO ;  Q92XJ0, ATKB_RHIME ;  B5EZE3, ATKB_SALA4 ;
DR   Q57RN0, ATKB_SALCH ;  B5FNE0, ATKB_SALDC ;  B5QWE9, ATKB_SALEP ;
DR   B5R670, ATKB_SALG2 ;  B4TBA6, ATKB_SALHS ;  B4SZB1, ATKB_SALNS ;
DR   Q5PCJ7, ATKB_SALPA ;  A9MUE0, ATKB_SALPB ;  B5BCA4, ATKB_SALPK ;
DR   B4TQ22, ATKB_SALSV ;  Q8Z8E5, ATKB_SALTI ;  Q8ZQW2, ATKB_SALTY ;
DR   A8GB61, ATKB_SERP5 ;  B2TTJ7, ATKB_SHIB3 ;  Q324L0, ATKB_SHIBS ;
DR   Q3Z4A6, ATKB_SHISS ;  Q2YUH7, ATKB_STAAB ;  Q5HEC4, ATKB_STAAC ;
DR   A6QIS1, ATKB_STAAE ;  Q6G7N3, ATKB_STAAS ;  A8Z4X9, ATKB_STAAT ;
DR   Q8NVI2, ATKB_STAAW ;  Q5HK64, ATKB_STAEQ ;  Q4LAI2, ATKB_STAHJ ;
DR   Q9X8Z9, ATKB_STRCO ;  P73867, ATKB_SYNY3 ;  P57700, ATKB_THEAC ;
DR   Q8R8I6, ATKB_THETN ;  Q97BF6, ATKB_THEVO ;  C4LDL7, ATKB_TOLAT ;
DR   Q8PPC9, ATKB_XANAC ;  Q8PCM1, ATKB_XANCP ;  A1JQS2, ATKB_YERE8 ;
DR   A7FFQ9, ATKB_YERP3 ;  Q1C586, ATKB_YERPA ;  B2KA78, ATKB_YERPB ;
DR   Q8ZD97, ATKB_YERPE ;  A9R3X3, ATKB_YERPG ;  Q1CKH2, ATKB_YERPN ;
DR   A4TL06, ATKB_YERPP ;  Q667S4, ATKB_YERPS ;  B1JR96, ATKB_YERPY ;
DR   Q8YSD7, ATKC1_NOSS1;  P65213, ATKC1_STAAM;  P65214, ATKC1_STAAN;
DR   Q8YPF1, ATKC2_NOSS1;  P0A059, ATKC2_STAAM;  P0A060, ATKC2_STAAU;
DR   Q1IUD3, ATKC_ACIBL ;  C1F0T4, ATKC_ACIC5 ;  B9JKQ9, ATKC_AGRRK ;
DR   Q8U9E0, ATKC_AGRT5 ;  B9K2I1, ATKC_AGRVS ;  Q9R6W9, ATKC_ANASL ;
DR   A8HY21, ATKC_AZOC5 ;  C3P0M1, ATKC_BACAA ;  C3LF98, ATKC_BACAC ;
DR   Q81UW5, ATKC_BACAN ;  B7JRB9, ATKC_BACC0 ;  Q73DA2, ATKC_BACC1 ;
DR   B7II10, ATKC_BACC2 ;  C1EYK1, ATKC_BACC3 ;  B7HDG0, ATKC_BACC4 ;
DR   B7HWG2, ATKC_BACC7 ;  A7GLG5, ATKC_BACCN ;  B9IQY6, ATKC_BACCQ ;
DR   Q81HP9, ATKC_BACCR ;  Q63FQ9, ATKC_BACCZ ;  Q5LHU5, ATKC_BACFN ;
DR   Q64YU7, ATKC_BACFR ;  Q6HN77, ATKC_BACHK ;  Q8A521, ATKC_BACTN ;
DR   A6L5D0, ATKC_BACV8 ;  A9VFM2, ATKC_BACWK ;  B2IIP7, ATKC_BEII9 ;
DR   Q89FC4, ATKC_BRAJA ;  A5EQ10, ATKC_BRASB ;  A4Z016, ATKC_BRASO ;
DR   B1YTU3, ATKC_BURA4 ;  Q1BUX7, ATKC_BURCA ;  B1JVS7, ATKC_BURCC ;
DR   A0K960, ATKC_BURCH ;  B4E5Q9, ATKC_BURCJ ;  Q0BD93, ATKC_BURCM ;
DR   A9AJK8, ATKC_BURM1 ;  A3MI57, ATKC_BURM7 ;  A2S4A3, ATKC_BURM9 ;
DR   Q62IJ8, ATKC_BURMA ;  A1V2H2, ATKC_BURMS ;  A3NT59, ATKC_BURP0 ;
DR   Q3JUE8, ATKC_BURP1 ;  A3N7H1, ATKC_BURP6 ;  B2JE25, ATKC_BURP8 ;
DR   B2T2B4, ATKC_BURPP ;  Q63VS1, ATKC_BURPS ;  Q2SZS2, ATKC_BURTA ;
DR   A4JGG7, ATKC_BURVG ;  Q142K7, ATKC_BURXL ;  B8GVG0, ATKC_CAUCN ;
DR   Q9A7X6, ATKC_CAUCR ;  B0SYJ5, ATKC_CAUSK ;  P94606, ATKC_CLOAB ;
DR   B2V2P4, ATKC_CLOBA ;  B2TMJ3, ATKC_CLOBB ;  Q186E8, ATKC_CLOD6 ;
DR   A5N884, ATKC_CLOK5 ;  Q0TRT2, ATKC_CLOP1 ;  Q47H40, ATKC_DECAR ;
DR   Q9RZN6, ATKC_DEIRA ;  B8DR36, ATKC_DESVM ;  A7ZJ79, ATKC_ECO24 ;
DR   B7UKX5, ATKC_ECO27 ;  B7MFW1, ATKC_ECO45 ;  B7LAA3, ATKC_ECO55 ;
DR   Q8X9G0, ATKC_ECO57 ;  B5YQN8, ATKC_ECO5E ;  B7NMP9, ATKC_ECO7I ;
DR   B7MPJ9, ATKC_ECO81 ;  B7M5L2, ATKC_ECO8A ;  C4ZWH2, ATKC_ECOBW ;
DR   B1X6M7, ATKC_ECODH ;  A7ZXV7, ATKC_ECOHS ;  Q0TJZ0, ATKC_ECOL5 ;
DR   Q8FJV5, ATKC_ECOL6 ;  B1IY33, ATKC_ECOLC ;  P03961, ATKC_ECOLI ;
DR   B7N9T9, ATKC_ECOLU ;  B6HYQ4, ATKC_ECOSE ;  B1LLE0, ATKC_ECOSM ;
DR   A4W859, ATKC_ENT38 ;  A7MQV0, ATKC_ENTS8 ;  Q6D7I5, ATKC_ERWCT ;
DR   B2VJK2, ATKC_ERWT9 ;  B7LKR8, ATKC_ESCF3 ;  A5FIF7, ATKC_FLAJ1 ;
DR   A6H084, ATKC_FLAPJ ;  C1ABQ7, ATKC_GEMAT ;  B5EH78, ATKC_GEOBB ;
DR   B3EAQ1, ATKC_GEOLS ;  Q39SW4, ATKC_GEOMG ;  Q74AA8, ATKC_GEOSL ;
DR   A5GAG0, ATKC_GEOUR ;  Q7NN39, ATKC_GLOVI ;  P57687, ATKC_HALSA ;
DR   A9AXV2, ATKC_HERA2 ;  A4G5J7, ATKC_HERAR ;  A6SZ14, ATKC_JANMA ;
DR   A6W6R7, ATKC_KINRD ;  B5XZF0, ATKC_KLEP3 ;  A6T6D7, ATKC_KLEP7 ;
DR   Q72TM5, ATKC_LEPIC ;  Q8F1M2, ATKC_LEPIN ;  Q927G1, ATKC_LISIN ;
DR   C1KZN4, ATKC_LISMC ;  Q71W91, ATKC_LISMF ;  B8DAW2, ATKC_LISMH ;
DR   Q8Y3Z8, ATKC_LISMO ;  A0AM15, ATKC_LISW6 ;  B7L1N2, ATKC_METC4 ;
DR   Q605R3, ATKC_METCA ;  A9VZA4, ATKC_METEP ;  B3DWJ8, ATKC_METI4 ;
DR   B8I9I8, ATKC_METNO ;  B1Z9X9, ATKC_METPB ;  B8GER0, ATKC_METPE ;
DR   A2SIS1, ATKC_METPP ;  B1M7D4, ATKC_METRJ ;  B8ETA0, ATKC_METSB ;
DR   B0JJA1, ATKC_MICAN ;  P65212, ATKC_MYCBO ;  A1KHH0, ATKC_MYCBP ;
DR   C1AM23, ATKC_MYCBT ;  A5U175, ATKC_MYCTA ;  P65211, ATKC_MYCTU ;
DR   Q93MV4, ATKC_MYXXA ;  Q1DFX4, ATKC_MYXXD ;  Q1QJ48, ATKC_NITHX ;
DR   A6X5I0, ATKC_OCHA4 ;  B6JA60, ATKC_OLICO ;  A7HRV5, ATKC_PARL1 ;
DR   Q7N6W7, ATKC_PHOLL ;  A1VTC0, ATKC_POLNA ;  A4SZG7, ATKC_POLSQ ;
DR   Q48K34, ATKC_PSE14 ;  B7UV86, ATKC_PSEA8 ;  Q02KC0, ATKC_PSEAB ;
DR   P57686, ATKC_PSEAE ;  Q1I7P1, ATKC_PSEE4 ;  A5W155, ATKC_PSEP1 ;
DR   B0KNU2, ATKC_PSEPG ;  Q88FD8, ATKC_PSEPK ;  B1JAS8, ATKC_PSEPW ;
DR   Q883V4, ATKC_PSESM ;  Q8XU10, ATKC_RALSO ;  Q98GX7, ATKC_RHILO ;
DR   Q92XJ1, ATKC_RHIME ;  B6IQY7, ATKC_RHOCS ;  Q07HN8, ATKC_RHOP5 ;
DR   Q6N5H2, ATKC_RHOPA ;  Q20XR6, ATKC_RHOPB ;  Q13DD7, ATKC_RHOPS ;
DR   B3Q8S9, ATKC_RHOPT ;  Q2RV87, ATKC_RHORT ;  A3PNW1, ATKC_RHOS1 ;
DR   Q3IYD8, ATKC_RHOS4 ;  B9KPZ0, ATKC_RHOSK ;  B5EZE2, ATKC_SALA4 ;
DR   Q57RN1, ATKC_SALCH ;  B5FND9, ATKC_SALDC ;  B5QWE8, ATKC_SALEP ;
DR   B5R669, ATKC_SALG2 ;  B4TBA5, ATKC_SALHS ;  B4SZB0, ATKC_SALNS ;
DR   A9MUE1, ATKC_SALPB ;  B4TQ21, ATKC_SALSV ;  Q8Z8E6, ATKC_SALTI ;
DR   Q8ZQW3, ATKC_SALTY ;  A8GB60, ATKC_SERP5 ;  A4YA10, ATKC_SHEPC ;
DR   Q32IN4, ATKC_SHIDS ;  Q0T6U0, ATKC_SHIF8 ;  Q3Z4A7, ATKC_SHISS ;
DR   Q2NW73, ATKC_SODGM ;  Q02CX5, ATKC_SOLUE ;  A9F781, ATKC_SORC5 ;
DR   Q2FF50, ATKC_STAA3 ;  Q2FWI1, ATKC_STAA8 ;  Q2YUH8, ATKC_STAAB ;
DR   Q5HEC5, ATKC_STAAC ;  A6QIS0, ATKC_STAAE ;  Q6GEZ8, ATKC_STAAR ;
DR   Q6G7N4, ATKC_STAAS ;  A8Z4X8, ATKC_STAAT ;  Q8NVI3, ATKC_STAAW ;
DR   Q5HK65, ATKC_STAEQ ;  Q4LAI1, ATKC_STAHJ ;  Q82PI5, ATKC_STRAW ;
DR   Q9X8Z8, ATKC_STRCO ;  P73869, ATKC_SYNY3 ;  P57688, ATKC_THEAC ;
DR   Q8R8I7, ATKC_THETN ;  Q97BF5, ATKC_THEVO ;  C5CPD2, ATKC_VARPS ;
DR   Q8PPC8, ATKC_XANAC ;  Q4UQV0, ATKC_XANC8 ;  B0RVC5, ATKC_XANCB ;
DR   Q8PCM0, ATKC_XANCP ;  Q2NZA0, ATKC_XANOM ;  A7IKC3, ATKC_XANP2 ;
DR   A1JQS4, ATKC_YERE8 ;  A7FFQ7, ATKC_YERP3 ;  Q8ZD98, ATKC_YERPE ;
//
ID   3.6.3.13
DE   Transferred entry: 3.6.3.1.
//
ID   3.6.3.14
DE   H(+)-transporting two-sector ATPase.
AN   ATP synthase.
AN   Chloroplast ATPase.
AN   F(0)F(1)-ATPase.
AN   F(1)-ATPase.
AN   F(o)F(1)-ATPase.
AN   H(+)-transporting ATP synthase.
AN   H(+)-transporting ATPase.
AN   Mitochondrial ATPase.
CA   ATP + H(2)O + H(+)(In) = ADP + phosphate + H(+)(Out).
CC   -!- A multisubunit non-phosphorylated ATPase that is involved in the
CC       transport of ions.
CC   -!- Large enzymes of mitochondria, chloroplasts and bacteria with a
CC       membrane sector (F(o), V(o), A(o)) and a cytoplasmic-compartment
CC       sector (F(1), V(1), A(1)).
CC   -!- The F-type enzymes of the inner mitochondrial and thylakoid membranes
CC       act as ATP synthases.
CC   -!- All of the enzymes included here operate in a rotational mode, where
CC       the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is
CC       connected via the delta-subunit to the membrane sector by several
CC       smaller subunits.
CC   -!- Within this complex, the gamma- and epsilon-subunits, as well as the
CC       9-12 c subunits rotate by consecutive 120 degree angles and perform
CC       parts of ATP synthesis.
CC   -!- This movement is driven by the H(+) electrochemical potential
CC       gradient.
CC   -!- The V-type (in vacuoles and clathrin-coated vesicles) and A-type
CC       (archaeal) enzymes have a similar structure but, under physiological
CC       conditions, they pump H(+) rather than synthesize ATP.
CC   -!- Formerly EC 3.6.1.34.
PR   PROSITE; PDOC00137;
PR   PROSITE; PDOC00138;
PR   PROSITE; PDOC00327;
PR   PROSITE; PDOC00420;
PR   PROSITE; PDOC00526;
DR   P60112, ATP9_ARATH ;  P14571, ATP9_BETVU ;  P60113, ATP9_BRANA ;
DR   P48880, ATP9_CHOCR ;  P17254, ATP9_HELAN ;  P00840, ATP9_MAIZE ;
DR   Q37550, ATP9_MALDO ;  P26855, ATP9_MARPO ;  P60115, ATP9_OENBI ;
DR   P0C518, ATP9_ORYSI ;  P0C519, ATP9_ORYSJ ;  P69420, ATP9_PEA   ;
DR   P60118, ATP9_PETHY ;  Q07060, ATP9_PETSP ;  P60117, ATP9_SOLLC ;
DR   P60114, ATP9_SOLTU ;  P69421, ATP9_SOYBN ;  P60116, ATP9_TOBAC ;
DR   P69422, ATP9_VICFA ;  P13547, ATP9_WHEAT ;  B0BZL2, ATPA1_ACAM1;
DR   A3MQJ7, ATPA1_BURM7;  Q62FR7, ATPA1_BURMA;  A1V8T3, ATPA1_BURMS;
DR   A3P0Z2, ATPA1_BURP0;  Q3JXV6, ATPA1_BURP1;  A3NF42, ATPA1_BURP6;
DR   Q63PH8, ATPA1_BURPS;  Q2STE7, ATPA1_BURTA;  Q13XV9, ATPA1_BURXL;
DR   A8LN46, ATPA1_DINSH;  Q5FRC7, ATPA1_GLUOX;  Q2SNG7, ATPA1_HAHCH;
DR   Q5X2Q3, ATPA1_LEGPA;  A5IFJ9, ATPA1_LEGPC;  Q5ZWN7, ATPA1_LEGPH;
DR   Q92FH0, ATPA1_LISIN;  Q724W6, ATPA1_LISMF;  Q8YAM8, ATPA1_LISMO;
DR   A0AFQ9, ATPA1_LISW6;  A6VWQ6, ATPA1_MARMS;  Q60CR6, ATPA1_METCA;
DR   Q98QU3, ATPA1_MYCPU;  Q0AJB2, ATPA1_NITEC;  Q2YCA5, ATPA1_NITMU;
DR   Q39ZT9, ATPA1_PELCD;  Q3B3Z9, ATPA1_PELLD;  Q6LLG6, ATPA1_PHOPR;
DR   A1VIV0, ATPA1_POLNA;  Q15SF1, ATPA1_PSEA6;  A1SS62, ATPA1_PSYIN;
DR   Q7UH05, ATPA1_RHOBA;  Q223D4, ATPA1_RHOFD;  A3PIB7, ATPA1_RHOS1;
DR   Q07YM0, ATPA1_SHEFN;  Q2LQZ7, ATPA1_SYNAS;  A7N0Y3, ATPA1_VIBHB;
DR   A8ZNS4, ATPA2_ACAM1;  A3MAS4, ATPA2_BURM7;  Q62EB0, ATPA2_BURMA;
DR   A1UY41, ATPA2_BURMS;  A3P8L5, ATPA2_BURP0;  Q3JJP7, ATPA2_BURP1;
DR   A3NN58, ATPA2_BURP6;  Q63IX0, ATPA2_BURPS;  Q2T873, ATPA2_BURTA;
DR   Q13SQ0, ATPA2_BURXL;  A8LJR6, ATPA2_DINSH;  Q5FNY6, ATPA2_GLUOX;
DR   Q2S6N9, ATPA2_HAHCH;  Q5X0P1, ATPA2_LEGPA;  A5III5, ATPA2_LEGPC;
DR   Q5ZR99, ATPA2_LEGPH;  Q927W2, ATPA2_LISIN;  Q71WP7, ATPA2_LISMF;
DR   Q8Y4C0, ATPA2_LISMO;  A0ALL5, ATPA2_LISW6;  A6W3T0, ATPA2_MARMS;
DR   Q603U2, ATPA2_METCA;  Q98QB7, ATPA2_MYCPU;  Q0AEI9, ATPA2_NITEC;
DR   Q2Y8G9, ATPA2_NITMU;  Q3A076, ATPA2_PELCD;  Q3B1F4, ATPA2_PELLD;
DR   Q6LKZ8, ATPA2_PHOPR;  A1VPQ8, ATPA2_POLNA;  Q15MU2, ATPA2_PSEA6;
DR   A1T0Z1, ATPA2_PSYIN;  Q7UFB7, ATPA2_RHOBA;  Q21Z99, ATPA2_RHOFD;
DR   A3PS65, ATPA2_RHOS1;  Q3HKH9, ATPA2_RHOS4;  Q07VU2, ATPA2_SHEFN;
DR   Q2LY34, ATPA2_SYNAS;  A7N6Q6, ATPA2_VIBHB;  Q13IW9, ATPA3_BURXL;
DR   A9NGW4, ATPA_ACHLI ;  A1TJ39, ATPA_ACIAC ;  Q6FFK2, ATPA_ACIAD ;
DR   B7H296, ATPA_ACIB3 ;  B7I1W2, ATPA_ACIB5 ;  B2I100, ATPA_ACIBC ;
DR   Q1IIG6, ATPA_ACIBL ;  A3M142, ATPA_ACIBT ;  B0VBP5, ATPA_ACIBY ;
DR   A0LSL4, ATPA_ACIC1 ;  C1F3N8, ATPA_ACIC5 ;  A5FZ52, ATPA_ACICJ ;
DR   B9MBA1, ATPA_ACIET ;  B7JB86, ATPA_ACIF2 ;  B5ER44, ATPA_ACIF5 ;
DR   A1W2T5, ATPA_ACISJ ;  A9LYH0, ATPA_ACOAM ;  Q3V549, ATPA_ACOCL ;
DR   A3N2U6, ATPA_ACTP2 ;  B3H2P5, ATPA_ACTP7 ;  B0BRX4, ATPA_ACTPJ ;
DR   A6VL59, ATPA_ACTSZ ;  Q85FN4, ATPA_ADICA ;  A0KQY0, ATPA_AERHH ;
DR   A4STP5, ATPA_AERS4 ;  A4QJA0, ATPA_AETCO ;  A4QJI4, ATPA_AETGR ;
DR   A1EA05, ATPA_AGRST ;  Q8UC74, ATPA_AGRT5 ;  B9JTR4, ATPA_AGRVS ;
DR   Q0VKX2, ATPA_ALCBS ;  Q0A4M6, ATPA_ALHEH ;  B6EHT9, ATPA_ALISL ;
DR   A6TK63, ATPA_ALKMQ ;  A8MJW1, ATPA_ALKOO ;  B4RS83, ATPA_ALTMD ;
DR   Q70XV0, ATPA_AMBTC ;  B3EU98, ATPA_AMOA5 ;  B8JCV2, ATPA_ANAD2 ;
DR   Q2IHQ9, ATPA_ANADE ;  A7HIX9, ATPA_ANADF ;  B9KH09, ATPA_ANAMF ;
DR   Q5P9M4, ATPA_ANAMM ;  Q2GIG2, ATPA_ANAPZ ;  B4UKF2, ATPA_ANASK ;
DR   Q3M9W0, ATPA_ANAVT ;  B0YPM5, ATPA_ANEMR ;  A2T317, ATPA_ANGEV ;
DR   B7GMF5, ATPA_ANOFW ;  Q85AU2, ATPA_ANTFO ;  Q02848, ATPA_ANTSP ;
DR   O66907, ATPA_AQUAE ;  A4QK03, ATPA_ARAHI ;  P56757, ATPA_ARATH ;
DR   A8EV72, ATPA_ARCB4 ;  Q5P4E4, ATPA_AROAE ;  A1R7V5, ATPA_ARTAT ;
DR   B8HAZ1, ATPA_ARTCA ;  A0JY66, ATPA_ARTS2 ;  Q8S8Y3, ATPA_ATRBE ;
DR   A8HS15, ATPA_AZOC5 ;  B6YR06, ATPA_AZOPC ;  A1K1S0, ATPA_AZOSB ;
DR   A7Z9Q2, ATPA_BACA2 ;  C3P1F6, ATPA_BACAA ;  C3LFI1, ATPA_BACAC ;
DR   A0RL97, ATPA_BACAH ;  Q81JZ3, ATPA_BACAN ;  B7JGN2, ATPA_BACC0 ;
DR   Q72XE6, ATPA_BACC1 ;  B7IQW0, ATPA_BACC2 ;  C1F0N0, ATPA_BACC3 ;
DR   B7HFK4, ATPA_BACC4 ;  B7HY67, ATPA_BACC7 ;  A7GV58, ATPA_BACCN ;
DR   B9IRT9, ATPA_BACCQ ;  Q814W0, ATPA_BACCR ;  Q630U1, ATPA_BACCZ ;
DR   Q5LD82, ATPA_BACFN ;  Q64UA4, ATPA_BACFR ;  Q9K6H3, ATPA_BACHD ;
DR   Q6HAX7, ATPA_BACHK ;  Q65DX2, ATPA_BACLD ;  P17674, ATPA_BACMQ ;
DR   A8FIB4, ATPA_BACP2 ;  P09219, ATPA_BACP3 ;  P22477, ATPA_BACPE ;
DR   Q5WB76, ATPA_BACSK ;  P37808, ATPA_BACSU ;  Q8A9U7, ATPA_BACTN ;
DR   A6L4M4, ATPA_BACV8 ;  A9VSA5, ATPA_BACWK ;  A1UR47, ATPA_BARBK ;
DR   Q6G1W7, ATPA_BARHE ;  Q6FYM1, ATPA_BARQU ;  A9IYX0, ATPA_BART1 ;
DR   A4QK90, ATPA_BARVE ;  Q1LTV2, ATPA_BAUCH ;  Q6MGM5, ATPA_BDEBA ;
DR   C5C1U6, ATPA_BEUC1 ;  B8DWS4, ATPA_BIFA0 ;  A1A3C7, ATPA_BIFAA ;
DR   B3DTV2, ATPA_BIFLD ;  Q8G7B1, ATPA_BIFLO ;  B7GTZ1, ATPA_BIFLS ;
DR   Q06J68, ATPA_BIGNA ;  Q7VQV8, ATPA_BLOFL ;  Q494C5, ATPA_BLOPB ;
DR   Q2KU34, ATPA_BORA1 ;  Q7WEM7, ATPA_BORBR ;  Q7W3A8, ATPA_BORPA ;
DR   A9HY40, ATPA_BORPD ;  Q7VU46, ATPA_BORPE ;  C0QW65, ATPA_BRAHW ;
DR   Q89X72, ATPA_BRAJA ;  A5E948, ATPA_BRASB ;  A4YKD8, ATPA_BRASO ;
DR   C0Z778, ATPA_BREBN ;  B2S7M5, ATPA_BRUA1 ;  Q2YLI5, ATPA_BRUA2 ;
DR   Q57B86, ATPA_BRUAB ;  A9M839, ATPA_BRUC2 ;  C0RF52, ATPA_BRUMB ;
DR   Q8YJ37, ATPA_BRUME ;  A5VSE3, ATPA_BRUO2 ;  A9WWS4, ATPA_BRUSI ;
DR   Q8FYR3, ATPA_BRUSU ;  P26965, ATPA_BRYMA ;  B8D8H1, ATPA_BUCA5 ;
DR   P57122, ATPA_BUCAI ;  O51874, ATPA_BUCAP ;  B8D6S5, ATPA_BUCAT ;
DR   Q89B41, ATPA_BUCBP ;  B1YQL2, ATPA_BURA4 ;  Q1BRA8, ATPA_BURCA ;
DR   B1JSV5, ATPA_BURCC ;  A0K2Y1, ATPA_BURCH ;  B4EEY7, ATPA_BURCJ ;
DR   Q0BJL7, ATPA_BURCM ;  A9AJG2, ATPA_BURM1 ;  A2S6K0, ATPA_BURM9 ;
DR   Q39KX8, ATPA_BURS3 ;  A4JA33, ATPA_BURVG ;  A6MM21, ATPA_BUXMI ;
DR   Q7YJY4, ATPA_CALFG ;  A7ZC35, ATPA_CAMC1 ;  A7H019, ATPA_CAMC5 ;
DR   A0RR28, ATPA_CAMFF ;  A7I175, ATPA_CAMHC ;  A8FJR0, ATPA_CAMJ8 ;
DR   A7H1H9, ATPA_CAMJD ;  Q9PJ21, ATPA_CAMJE ;  A1VXI8, ATPA_CAMJJ ;
DR   Q5HX61, ATPA_CAMJR ;  B9KES1, ATPA_CAMLR ;  A4QKH7, ATPA_CAPBU ;
DR   Q3A944, ATPA_CARHZ ;  B1A920, ATPA_CARPA ;  Q05FY3, ATPA_CARRP ;
DR   B8H5I2, ATPA_CAUCN ;  Q9A2V7, ATPA_CAUCR ;  B0T338, ATPA_CAUSK ;
DR   B3PIS9, ATPA_CELJU ;  A8SE59, ATPA_CERDE ;  Q8MA05, ATPA_CHAGL ;
DR   Q1ACM8, ATPA_CHAVU ;  A9WGS6, ATPA_CHLAA ;  B8G6G8, ATPA_CHLAD ;
DR   Q19VA5, ATPA_CHLAT ;  Q3AUA7, ATPA_CHLCH ;  B3EHU6, ATPA_CHLL2 ;
DR   B3EL39, ATPA_CHLPB ;  A1BJF5, ATPA_CHLPD ;  P26526, ATPA_CHLRE ;
DR   A6MMA7, ATPA_CHLSC ;  B3QWX7, ATPA_CHLT3 ;  Q8KAW8, ATPA_CHLTE ;
DR   P56294, ATPA_CHLVU ;  Q1QSC8, ATPA_CHRSD ;  Q7P097, ATPA_CHRVO ;
DR   A8ACN8, ATPA_CITK8 ;  Q09MJ3, ATPA_CITSI ;  A5CQ58, ATPA_CLAM3 ;
DR   B0RED6, ATPA_CLAMS ;  Q9Z689, ATPA_CLOAB ;  A7FQH7, ATPA_CLOB1 ;
DR   C3KYJ1, ATPA_CLOB6 ;  A6LQH4, ATPA_CLOB8 ;  B2UZJ8, ATPA_CLOBA ;
DR   B2TJZ8, ATPA_CLOBB ;  A5HY50, ATPA_CLOBH ;  C1FQP3, ATPA_CLOBJ ;
DR   B1IE32, ATPA_CLOBK ;  A7G9Q7, ATPA_CLOBL ;  B1KSS6, ATPA_CLOBM ;
DR   Q180W8, ATPA_CLOD6 ;  B9DX63, ATPA_CLOK1 ;  A5N3H9, ATPA_CLOK5 ;
DR   A0Q2Z6, ATPA_CLONN ;  Q0TNC2, ATPA_CLOP1 ;  Q8XID2, ATPA_CLOPE ;
DR   A9KK94, ATPA_CLOPH ;  Q0SQZ3, ATPA_CLOPS ;  A3DIM7, ATPA_CLOTH ;
DR   A0A320, ATPA_COFAR ;  Q48AW2, ATPA_COLP3 ;  C3PFR3, ATPA_CORA7 ;
DR   Q6NHT1, ATPA_CORDI ;  Q8FQ22, ATPA_COREF ;  A4QDH1, ATPA_CORGB ;
DR   Q79VG7, ATPA_CORGL ;  Q4JUJ8, ATPA_CORJK ;  B1VFY5, ATPA_CORU7 ;
DR   B6J961, ATPA_COXB1 ;  B6J2D8, ATPA_COXB2 ;  A9KBF9, ATPA_COXBN ;
DR   A9NBC8, ATPA_COXBR ;  Q83AF7, ATPA_COXBU ;  A4QKR6, ATPA_CRUWA ;
DR   Q2QDA3, ATPA_CUCSA ;  Q0K5M5, ATPA_CUPNH ;  Q46VX8, ATPA_CUPPJ ;
DR   A8W3A9, ATPA_CUSEX ;  A7M8Y9, ATPA_CUSGR ;  A8W3H5, ATPA_CUSOB ;
DR   A7M951, ATPA_CUSRE ;  Q9TM26, ATPA_CYACA ;  Q85FQ8, ATPA_CYAME ;
DR   B8HPK1, ATPA_CYAP4 ;  B7KKR4, ATPA_CYAP7 ;  B7K5I8, ATPA_CYAP8 ;
DR   P48080, ATPA_CYAPA ;  A6H5F1, ATPA_CYCTA ;  Q11YP1, ATPA_CYTH3 ;
DR   Q0G9X7, ATPA_DAUCA ;  Q477Z3, ATPA_DECAR ;  Q3Z8Z4, ATPA_DEHE1 ;
DR   A5FRQ3, ATPA_DEHSB ;  Q3ZZT9, ATPA_DEHSC ;  A9BPU5, ATPA_DELAS ;
DR   B8FGT6, ATPA_DESAA ;  B1I6J9, ATPA_DESAP ;  B8J437, ATPA_DESDA ;
DR   Q313V8, ATPA_DESDG ;  B8FZ36, ATPA_DESHD ;  Q24MN9, ATPA_DESHY ;
DR   C4XI08, ATPA_DESMR ;  A8ZU99, ATPA_DESOH ;  Q6AQ12, ATPA_DESPS ;
DR   A4J9A1, ATPA_DESRM ;  Q72E02, ATPA_DESVH ;  B8DRD0, ATPA_DESVM ;
DR   A1VFJ3, ATPA_DESVV ;  A5EXJ7, ATPA_DICNV ;  B5YBQ0, ATPA_DICT6 ;
DR   B8DYT2, ATPA_DICTD ;  A6MMJ2, ATPA_DIOEL ;  A4QL04, ATPA_DRANE ;
DR   Q06H12, ATPA_DRIGR ;  A7ZTU6, ATPA_ECO24 ;  B7UMJ9, ATPA_ECO27 ;
DR   B7MGF4, ATPA_ECO45 ;  B7L884, ATPA_ECO55 ;  P0ABB2, ATPA_ECO57 ;
DR   B5YXD8, ATPA_ECO5E ;  B7NR36, ATPA_ECO7I ;  B7N2H3, ATPA_ECO81 ;
DR   B7M590, ATPA_ECO8A ;  C4ZZ12, ATPA_ECOBW ;  B1X9W2, ATPA_ECODH ;
DR   A8A6J7, ATPA_ECOHS ;  Q0TAX5, ATPA_ECOL5 ;  P0ABB1, ATPA_ECOL6 ;
DR   B1IX04, ATPA_ECOLC ;  P0ABB0, ATPA_ECOLI ;  B7NF50, ATPA_ECOLU ;
DR   B6I3X1, ATPA_ECOSE ;  B1LL61, ATPA_ECOSM ;  Q1R4K0, ATPA_ECOUT ;
DR   C5BF38, ATPA_EDWI9 ;  Q3YT21, ATPA_EHRCJ ;  Q2GHX3, ATPA_EHRCR ;
DR   Q5FF66, ATPA_EHRRG ;  Q5HC95, ATPA_EHRRW ;  B2KEX0, ATPA_ELUMP ;
DR   Q4G397, ATPA_EMIHU ;  A4WGF3, ATPA_ENT38 ;  Q831A3, ATPA_ENTFA ;
DR   P26679, ATPA_ENTHR ;  A7MMX1, ATPA_ENTS8 ;  Q6CYJ3, ATPA_ERWCT ;
DR   B2VCA6, ATPA_ERWT9 ;  Q2N8Z5, ATPA_ERYLH ;  B7LK79, ATPA_ESCF3 ;
DR   Q49L13, ATPA_EUCGG ;  P30392, ATPA_EUGGR ;  B1YMR6, ATPA_EXIS2 ;
DR   C4KYS5, ATPA_EXISA ;  A7HJV9, ATPA_FERNB ;  A5FL34, ATPA_FLAJ1 ;
DR   A6H2D7, ATPA_FLAPJ ;  Q0RDB2, ATPA_FRAAA ;  B0TWS5, ATPA_FRAP2 ;
DR   Q2J6N1, ATPA_FRASC ;  A8L3W3, ATPA_FRASN ;  Q14K08, ATPA_FRAT1 ;
DR   A7NEH6, ATPA_FRATF ;  Q2A1I0, ATPA_FRATH ;  B2SEX9, ATPA_FRATM ;
DR   A0Q8E1, ATPA_FRATN ;  Q0BK82, ATPA_FRATO ;  Q5NIK5, ATPA_FRATT ;
DR   A4IW22, ATPA_FRATW ;  Q8RGE0, ATPA_FUSNN ;  P35009, ATPA_GALSU ;
DR   B5EFI9, ATPA_GEOBB ;  Q5KUJ1, ATPA_GEOKA ;  B3EA03, ATPA_GEOLS ;
DR   Q39Q54, ATPA_GEOMG ;  P42005, ATPA_GEOSE ;  B9LZ86, ATPA_GEOSF ;
DR   Q74GY2, ATPA_GEOSL ;  C6E9F3, ATPA_GEOSM ;  C5D992, ATPA_GEOSW ;
DR   A4ITJ1, ATPA_GEOTN ;  A5G9D6, ATPA_GEOUR ;  Q7NCS3, ATPA_GLOVI ;
DR   A9H9A4, ATPA_GLUDA ;  A6BM08, ATPA_GNEPA ;  A0ZZ20, ATPA_GOSBA ;
DR   Q2L8Z1, ATPA_GOSHI ;  Q0BQE6, ATPA_GRABC ;  A0M6G4, ATPA_GRAFK ;
DR   Q6B8Q8, ATPA_GRATL ;  O78475, ATPA_GUITH ;  Q7VPP2, ATPA_HAEDU ;
DR   Q4QN62, ATPA_HAEI8 ;  A5UA09, ATPA_HAEIE ;  A5UGZ1, ATPA_HAEIG ;
DR   P43714, ATPA_HAEIN ;  B8F772, ATPA_HAEPS ;  Q0I5X1, ATPA_HAES1 ;
DR   B0UWG7, ATPA_HAES2 ;  A1WZT3, ATPA_HALHL ;  B8CZ12, ATPA_HALOH ;
DR   Q17Y80, ATPA_HELAH ;  Q1KXW5, ATPA_HELAN ;  Q7VJ23, ATPA_HELHP ;
DR   B0THN4, ATPA_HELMI ;  B6JMX4, ATPA_HELP2 ;  B5Z8D2, ATPA_HELPG ;
DR   Q1CSD3, ATPA_HELPH ;  Q9ZK79, ATPA_HELPJ ;  B2UUP2, ATPA_HELPS ;
DR   P55987, ATPA_HELPY ;  A9AVV2, ATPA_HERA2 ;  A4GAH1, ATPA_HERAR ;
DR   A1E9I8, ATPA_HORVU ;  Q5SCX6, ATPA_HUPLU ;  B4U989, ATPA_HYDS0 ;
DR   Q0C0Z8, ATPA_HYPNA ;  Q5QZI4, ATPA_IDILO ;  A6MMS9, ATPA_ILLOL ;
DR   A7Y3A4, ATPA_IPOPU ;  A6T472, ATPA_JANMA ;  Q28TJ8, ATPA_JANSC ;
DR   Q06RE6, ATPA_JASNU ;  A6W7G7, ATPA_KINRD ;  B5XZM2, ATPA_KLEP3 ;
DR   A6TG38, ATPA_KLEP7 ;  B2GLY8, ATPA_KOCRD ;  C5CIV6, ATPA_KOSOT ;
DR   Q5FKY2, ATPA_LACAC ;  Q03QY6, ATPA_LACBA ;  Q03A20, ATPA_LACC3 ;
DR   B3WDL6, ATPA_LACCB ;  Q1GAW7, ATPA_LACDA ;  Q04BA5, ATPA_LACDB ;
DR   B2GAU3, ATPA_LACF3 ;  Q042L3, ATPA_LACGA ;  A8YUJ9, ATPA_LACH4 ;
DR   Q74K17, ATPA_LACJO ;  Q9CER8, ATPA_LACLA ;  A2RMI4, ATPA_LACLM ;
DR   Q02XA3, ATPA_LACLS ;  Q88UU1, ATPA_LACPL ;  A5VIQ9, ATPA_LACRD ;
DR   B2G689, ATPA_LACRJ ;  Q1WUC8, ATPA_LACS1 ;  Q332Y4, ATPA_LACSA ;
DR   Q38WK3, ATPA_LACSS ;  C1D5G4, ATPA_LARHH ;  Q1MRB9, ATPA_LAWIP ;
DR   Q5WSG6, ATPA_LEGPL ;  Q6AG60, ATPA_LEIXX ;  A9L981, ATPA_LEMMI ;
DR   B0SDA3, ATPA_LEPBA ;  Q04S16, ATPA_LEPBJ ;  Q04ZU3, ATPA_LEPBL ;
DR   B0SLC6, ATPA_LEPBP ;  B1Y3S9, ATPA_LEPCP ;  Q72SY1, ATPA_LEPIC ;
DR   Q8F2J2, ATPA_LEPIN ;  A6YG64, ATPA_LEPTE ;  A4QL91, ATPA_LEPVR ;
DR   B1MW87, ATPA_LEUCK ;  Q03V27, ATPA_LEUMM ;  Q0G9N4, ATPA_LIRTU ;
DR   A4QLH9, ATPA_LOBMA ;  A8Y9G7, ATPA_LOLPR ;  Q9BBS3, ATPA_LOTJA ;
DR   B1HM54, ATPA_LYSSC ;  B9E8E8, ATPA_MACCJ ;  Q2VZN0, ATPA_MAGSA ;
DR   A0LDA2, ATPA_MAGSM ;  P05022, ATPA_MAIZE ;  B1NWD5, ATPA_MANES ;
DR   Q65Q05, ATPA_MANSM ;  A1U7H6, ATPA_MARAV ;  Q0AKV8, ATPA_MARMM ;
DR   P06283, ATPA_MARPO ;  Q6F204, ATPA_MESFL ;  Q11DD7, ATPA_MESSB ;
DR   Q9MUT2, ATPA_MESVI ;  B7KUA4, ATPA_METC4 ;  A9W2R3, ATPA_METEP ;
DR   Q1GXM8, ATPA_METFK ;  B8IN03, ATPA_METNO ;  B1ZEE9, ATPA_METPB ;
DR   A2SC68, ATPA_METPP ;  B1LVH1, ATPA_METRJ ;  B0UE41, ATPA_METS4 ;
DR   B8EQP9, ATPA_METSB ;  B0JWV1, ATPA_MICAN ;  Q2RFX7, ATPA_MOOTA ;
DR   Q09X32, ATPA_MORIN ;  A0QCX6, ATPA_MYCA1 ;  B3PLV6, ATPA_MYCA5 ;
DR   B1MLW0, ATPA_MYCA9 ;  A5IYE3, ATPA_MYCAP ;  P63674, ATPA_MYCBO ;
DR   A1KI96, ATPA_MYCBP ;  C1AMV2, ATPA_MYCBT ;  Q2ST36, ATPA_MYCCT ;
DR   P33252, ATPA_MYCGA ;  P47641, ATPA_MYCGE ;  A4T8K0, ATPA_MYCGI ;
DR   Q601Z7, ATPA_MYCH2 ;  Q4A8W1, ATPA_MYCH7 ;  Q4AAV9, ATPA_MYCHJ ;
DR   B8ZR40, ATPA_MYCLB ;  P45825, ATPA_MYCLE ;  B2HQK4, ATPA_MYCMM ;
DR   Q6KI79, ATPA_MYCMO ;  Q6MS92, ATPA_MYCMS ;  Q73X57, ATPA_MYCPA ;
DR   Q8EWZ0, ATPA_MYCPE ;  Q50329, ATPA_MYCPN ;  A0R202, ATPA_MYCS2 ;
DR   Q4A602, ATPA_MYCS5 ;  A3Q3B3, ATPA_MYCSJ ;  A1UJY6, ATPA_MYCSK ;
DR   Q1B551, ATPA_MYCSS ;  A5U207, ATPA_MYCTA ;  P63673, ATPA_MYCTU ;
DR   A0PUK2, ATPA_MYCUA ;  A1TD57, ATPA_MYCVP ;  Q07405, ATPA_MYXXA ;
DR   Q1CWT2, ATPA_MYXXD ;  Q09FX6, ATPA_NANDO ;  A4QLR8, ATPA_NASOF ;
DR   B2A3G4, ATPA_NATTJ ;  Q5F4Z2, ATPA_NEIG1 ;  A9M121, ATPA_NEIM0 ;
DR   Q9JW72, ATPA_NEIMA ;  Q9JXQ0, ATPA_NEIMB ;  A1KW13, ATPA_NEIMF ;
DR   Q2GER5, ATPA_NEOSM ;  Q9TL16, ATPA_NEPOL ;  Q3C1H4, ATPA_NICSY ;
DR   Q33C53, ATPA_NICTO ;  Q82XQ0, ATPA_NITEU ;  Q1QQS5, ATPA_NITHX ;
DR   Q3J6M9, ATPA_NITOC ;  A6Q4C2, ATPA_NITSB ;  Q3SVJ4, ATPA_NITWN ;
DR   Q5Z0Y3, ATPA_NOCFA ;  A1SHI9, ATPA_NOCSJ ;  B2J058, ATPA_NOSP7 ;
DR   P12405, ATPA_NOSS1 ;  Q2G5N7, ATPA_NOVAD ;  A1XFU0, ATPA_NUPAD ;
DR   Q6EW63, ATPA_NYMAL ;  Q8EM81, ATPA_OCEIH ;  A6WXW9, ATPA_OCHA4 ;
DR   Q40611, ATPA_OCHNE ;  Q00820, ATPA_ODOSI ;  B0Z4N2, ATPA_OENAR ;
DR   B0Z4W6, ATPA_OENBI ;  Q9MTL7, ATPA_OENEH ;  B0Z550, ATPA_OENGL ;
DR   Q04G22, ATPA_OENOB ;  B0Z5D4, ATPA_OENPA ;  B6JD06, ATPA_OLICO ;
DR   A4QJR8, ATPA_OLIPU ;  Q20EV9, ATPA_OLTVI ;  A5CD07, ATPA_ORITB ;
DR   B3CSS9, ATPA_ORITI ;  Q6ENH7, ATPA_ORYNI ;  P0C2Z4, ATPA_ORYSA ;
DR   P0C2Z5, ATPA_ORYSI ;  P0C2Z6, ATPA_ORYSJ ;  Q0P3K5, ATPA_OSTTA ;
DR   Q68S21, ATPA_PANGI ;  A6L8N5, ATPA_PARD8 ;  A1B8N8, ATPA_PARDP ;
DR   A7HT50, ATPA_PARL1 ;  Q6MAK5, ATPA_PARUW ;  Q9CKW2, ATPA_PASMU ;
DR   P08215, ATPA_PEA   ;  C6DJH0, ATPA_PECCP ;  Q03EL2, ATPA_PEDPA ;
DR   Q06FX6, ATPA_PELHO ;  B4SGC7, ATPA_PELPB ;  A1ALL5, ATPA_PELPD ;
DR   A5CYE4, ATPA_PELTS ;  Q4FP36, ATPA_PELUB ;  A9BFX5, ATPA_PETMO ;
DR   Q3BAQ7, ATPA_PHAAO ;  A0T0F1, ATPA_PHATC ;  A4GGB2, ATPA_PHAVU ;
DR   B4RD45, ATPA_PHEZH ;  Q7NA92, ATPA_PHOLL ;  Q6YXK3, ATPA_PHYPA ;
DR   Q85X67, ATPA_PINKO ;  P41602, ATPA_PINTH ;  Q06GS5, ATPA_PIPCE ;
DR   Q09G61, ATPA_PLAOC ;  B1XSD2, ATPA_POLNS ;  Q12GQ2, ATPA_POLSJ ;
DR   A4SUT2, ATPA_POLSQ ;  Q14FH2, ATPA_POPAL ;  P84582, ATPA_POPEU ;
DR   A4GYP3, ATPA_POPTR ;  P51242, ATPA_PORPU ;  Q1XDP5, ATPA_PORYE ;
DR   Q6A8C5, ATPA_PROAC ;  A3PET9, ATPA_PROM0 ;  A2C4J5, ATPA_PROM1 ;
DR   A8G6V1, ATPA_PROM2 ;  A2C6X5, ATPA_PROM3 ;  A9BCD9, ATPA_PROM4 ;
DR   A2BYH6, ATPA_PROM5 ;  Q318U1, ATPA_PROM9 ;  Q7VA63, ATPA_PROMA ;
DR   B4F0E5, ATPA_PROMH ;  Q7V5S7, ATPA_PROMM ;  Q7V037, ATPA_PROMP ;
DR   A2BT25, ATPA_PROMS ;  Q46J57, ATPA_PROMT ;  A4SGM9, ATPA_PROVI ;
DR   O99015, ATPA_PROWI ;  Q48BG3, ATPA_PSE14 ;  A6VF34, ATPA_PSEA7 ;
DR   B7V793, ATPA_PSEA8 ;  Q02DF2, ATPA_PSEAB ;  Q9HT18, ATPA_PSEAE ;
DR   Q3ZJ00, ATPA_PSEAK ;  Q1I2I5, ATPA_PSEE4 ;  Q4K3A7, ATPA_PSEF5 ;
DR   C3K1E8, ATPA_PSEFS ;  Q3IK48, ATPA_PSEHT ;  A4Y189, ATPA_PSEMY ;
DR   A5WBA5, ATPA_PSEP1 ;  Q3K439, ATPA_PSEPF ;  B0KRB0, ATPA_PSEPG ;
DR   Q88BX2, ATPA_PSEPK ;  B1JFU3, ATPA_PSEPW ;  Q87TT2, ATPA_PSESM ;
DR   Q4ZL22, ATPA_PSEU2 ;  A4VS64, ATPA_PSEU5 ;  Q8WI30, ATPA_PSINU ;
DR   Q4FQ35, ATPA_PSYA2 ;  Q1Q897, ATPA_PSYCK ;  A5WBV9, ATPA_PSYWF ;
DR   Q1LHK8, ATPA_RALME ;  B2UGV1, ATPA_RALPJ ;  Q8XU74, ATPA_RALSO ;
DR   A1XGM3, ATPA_RANMC ;  A9WNC6, ATPA_RENSM ;  A6MVW4, ATPA_RHDSA ;
DR   B3PQ70, ATPA_RHIE6 ;  Q2K3G8, ATPA_RHIEC ;  Q1MAZ0, ATPA_RHIL3 ;
DR   Q98EV6, ATPA_RHILO ;  B5ZSN9, ATPA_RHILW ;  Q92LK6, ATPA_RHIME ;
DR   C3M9S3, ATPA_RHISN ;  P05439, ATPA_RHOBL ;  P72245, ATPA_RHOCA ;
DR   C1A1Y0, ATPA_RHOE4 ;  C1AW01, ATPA_RHOOB ;  Q2J3I2, ATPA_RHOP2 ;
DR   Q07UZ3, ATPA_RHOP5 ;  Q6NDD0, ATPA_RHOPA ;  Q21CY5, ATPA_RHOPB ;
DR   Q13DP4, ATPA_RHOPS ;  Q2RV20, ATPA_RHORT ;  P05036, ATPA_RHORU ;
DR   Q3J433, ATPA_RHOS4 ;  A4WUM9, ATPA_RHOS5 ;  B9KPI6, ATPA_RHOSK ;
DR   Q0SGP7, ATPA_RHOSR ;  A8GPZ6, ATPA_RICAH ;  A8GY42, ATPA_RICB8 ;
DR   A8F006, ATPA_RICCK ;  Q92G86, ATPA_RICCN ;  Q4UK16, ATPA_RICFE ;
DR   A8F2U2, ATPA_RICM5 ;  O50288, ATPA_RICPR ;  C4K229, ATPA_RICPU ;
DR   B0BVB8, ATPA_RICRO ;  A8GTS8, ATPA_RICRS ;  Q68VU6, ATPA_RICTY ;
DR   A7NIR1, ATPA_ROSCS ;  Q162S7, ATPA_ROSDO ;  A5UQN5, ATPA_ROSS1 ;
DR   Q1AVH7, ATPA_RUBXD ;  A1AXU4, ATPA_RUTMC ;  Q21DK6, ATPA_SACD2 ;
DR   A4FN29, ATPA_SACEN ;  Q6L3A1, ATPA_SACHY ;  Q6ENW6, ATPA_SACOF ;
DR   B5EYZ8, ATPA_SALA4 ;  A8M2J5, ATPA_SALAI ;  A9MJR7, ATPA_SALAR ;
DR   Q57HX7, ATPA_SALCH ;  B5FN35, ATPA_SALDC ;  B5QUS6, ATPA_SALEP ;
DR   B5RFW1, ATPA_SALG2 ;  B4TAX4, ATPA_SALHS ;  B4SYD3, ATPA_SALNS ;
DR   Q5PKX0, ATPA_SALPA ;  A9MXA8, ATPA_SALPB ;  C0Q2N4, ATPA_SALPC ;
DR   B5BIN8, ATPA_SALPK ;  Q2S432, ATPA_SALRD ;  B4TN33, ATPA_SALSV ;
DR   Q8XG95, ATPA_SALTI ;  A4XAW4, ATPA_SALTO ;  Q7CPE1, ATPA_SALTY ;
DR   Q1KVU0, ATPA_SCEOB ;  Q2WGJ0, ATPA_SELUN ;  A8G7M6, ATPA_SERP5 ;
DR   A1SBU2, ATPA_SHEAM ;  B8EDV2, ATPA_SHEB2 ;  A3DAR6, ATPA_SHEB5 ;
DR   A6WUJ2, ATPA_SHEB8 ;  A9KX08, ATPA_SHEB9 ;  Q12HP9, ATPA_SHEDO ;
DR   B0TQF6, ATPA_SHEHH ;  A3QJR2, ATPA_SHELP ;  Q8E8B8, ATPA_SHEON ;
DR   A8HAG5, ATPA_SHEPA ;  A4YCI0, ATPA_SHEPC ;  B8CVU7, ATPA_SHEPW ;
DR   A0L2T0, ATPA_SHESA ;  A8G1W7, ATPA_SHESH ;  Q0HD77, ATPA_SHESM ;
DR   Q0HPF9, ATPA_SHESR ;  A1RQB2, ATPA_SHESW ;  B1KQ36, ATPA_SHEWM ;
DR   B2TUP1, ATPA_SHIB3 ;  Q31UN4, ATPA_SHIBS ;  Q329S3, ATPA_SHIDS ;
DR   Q0SYU2, ATPA_SHIF8 ;  P0ABB3, ATPA_SHIFL ;  Q3YVN8, ATPA_SHISS ;
DR   Q589B3, ATPA_SILLA ;  Q5LNN9, ATPA_SILPO ;  Q1GEU6, ATPA_SILST ;
DR   A6UDM3, ATPA_SINMW ;  Q2NQ88, ATPA_SODGM ;  Q2MIK2, ATPA_SOLBU ;
DR   Q2MIB5, ATPA_SOLLC ;  Q27S65, ATPA_SOLTU ;  Q02BU3, ATPA_SOLUE ;
DR   A1E9S1, ATPA_SORBI ;  A9GHR6, ATPA_SORC5 ;  Q2PMS8, ATPA_SOYBN ;
DR   Q1GQS7, ATPA_SPHAL ;  A5V3X3, ATPA_SPHWW ;  P06450, ATPA_SPIOL ;
DR   A7X4U5, ATPA_STAA1 ;  A6U3J0, ATPA_STAA2 ;  Q2FF22, ATPA_STAA3 ;
DR   Q2FWE8, ATPA_STAA8 ;  A5IUQ0, ATPA_STAA9 ;  Q2YUJ9, ATPA_STAAB ;
DR   Q5HE95, ATPA_STAAC ;  A6QIU9, ATPA_STAAE ;  P63675, ATPA_STAAM ;
DR   P99111, ATPA_STAAN ;  Q6GEX0, ATPA_STAAR ;  Q6G7K5, ATPA_STAAS ;
DR   A8YY72, ATPA_STAAT ;  P63676, ATPA_STAAW ;  Q5HMB7, ATPA_STAEQ ;
DR   Q8CNJ5, ATPA_STAES ;  Q4L7Y6, ATPA_STAHJ ;  Q32RS8, ATPA_STAPU ;
DR   Q49Z52, ATPA_STAS1 ;  Q06SI2, ATPA_STIHE ;  Q3K1J7, ATPA_STRA1 ;
DR   Q8E5V0, ATPA_STRA3 ;  Q8E074, ATPA_STRA5 ;  Q82J82, ATPA_STRAW ;
DR   Q9K4D5, ATPA_STRCO ;  C0M718, ATPA_STRE4 ;  B4U2D9, ATPA_STREM ;
DR   A8AYG3, ATPA_STRGC ;  B1W0A5, ATPA_STRGG ;  P50001, ATPA_STRLI ;
DR   B4SJS1, ATPA_STRM5 ;  B2FHZ0, ATPA_STRMK ;  P95787, ATPA_STRMU ;
DR   Q9A0I9, ATPA_STRP1 ;  Q04HT7, ATPA_STRP2 ;  P0DA02, ATPA_STRP3 ;
DR   B5E673, ATPA_STRP4 ;  Q5XCY2, ATPA_STRP6 ;  C1C8A1, ATPA_STRP7 ;
DR   Q8P1K6, ATPA_STRP8 ;  Q1JCL5, ATPA_STRPB ;  Q1JMJ1, ATPA_STRPC ;
DR   Q1JHN7, ATPA_STRPD ;  Q1J7G1, ATPA_STRPF ;  A2RFC4, ATPA_STRPG ;
DR   B1ICT1, ATPA_STRPI ;  B8ZLB1, ATPA_STRPJ ;  Q48UD5, ATPA_STRPM ;
DR   Q97PT4, ATPA_STRPN ;  P0DA03, ATPA_STRPQ ;  B2IQX2, ATPA_STRPS ;
DR   B5XKP9, ATPA_STRPZ ;  Q7CRB1, ATPA_STRR6 ;  A4W1V9, ATPA_STRS2 ;
DR   C0MH19, ATPA_STRS7 ;  A4VVK1, ATPA_STRSY ;  Q5M106, ATPA_STRT1 ;
DR   Q5M5J3, ATPA_STRT2 ;  Q03LX5, ATPA_STRTD ;  B9DRT4, ATPA_STRU0 ;
DR   C1CF95, ATPA_STRZJ ;  C1CLK8, ATPA_STRZP ;  C1CSD0, ATPA_STRZT ;
DR   Q30QP9, ATPA_SULDN ;  A8Z5R1, ATPA_SULMW ;  A6QB61, ATPA_SULNB ;
DR   B2V6N6, ATPA_SULSY ;  Q67TB9, ATPA_SYMTH ;  Q31RF1, ATPA_SYNE7 ;
DR   A0LLG0, ATPA_SYNFM ;  Q2JSW1, ATPA_SYNJA ;  Q2JIG0, ATPA_SYNJB ;
DR   Q05372, ATPA_SYNP1 ;  P08449, ATPA_SYNP6 ;  A5GNC8, ATPA_SYNPW ;
DR   Q7U8W5, ATPA_SYNPX ;  A5GV72, ATPA_SYNR3 ;  Q0I7R2, ATPA_SYNS3 ;
DR   Q3AZM1, ATPA_SYNS9 ;  Q3AHK5, ATPA_SYNSC ;  Q0AUD1, ATPA_SYNWW ;
DR   P27179, ATPA_SYNY3 ;  C5BKJ7, ATPA_TERTT ;  A0T0P4, ATPA_THAPS ;
DR   B7IG42, ATPA_THEAB ;  Q8DLP3, ATPA_THEEB ;  Q47M80, ATPA_THEFY ;
DR   A8F3K0, ATPA_THELT ;  A6LJR3, ATPA_THEM4 ;  Q9X1U7, ATPA_THEMA ;
DR   B9K7T9, ATPA_THENN ;  A5ILX0, ATPA_THEP1 ;  B9L1H1, ATPA_THERP ;
DR   B1LBC1, ATPA_THESQ ;  Q8RC17, ATPA_THETN ;  B5YI22, ATPA_THEYD ;
DR   Q31DL8, ATPA_THICR ;  Q3SF64, ATPA_THIDA ;  P41167, ATPA_THIFE ;
DR   B8GRC0, ATPA_THISH ;  P00823, ATPA_TOBAC ;  C4LDW2, ATPA_TOLAT ;
DR   Q112Z6, ATPA_TRIEI ;  Q83HY2, ATPA_TROW8 ;  Q83G89, ATPA_TROWT ;
DR   B1AIC1, ATPA_UREP2 ;  Q9PR12, ATPA_UREPA ;  C5CNB3, ATPA_VARPS ;
DR   A1WF56, ATPA_VEREI ;  A5CVI8, ATPA_VESOH ;  P12985, ATPA_VIBAL ;
DR   A5F457, ATPA_VIBC3 ;  Q9KNH3, ATPA_VIBCH ;  Q5E1N5, ATPA_VIBF1 ;
DR   B5FCZ3, ATPA_VIBFM ;  Q87KA6, ATPA_VIBPA ;  Q8DDH0, ATPA_VIBVU ;
DR   Q7MGH8, ATPA_VIBVY ;  Q0ZJ35, ATPA_VITVI ;  B2Y1W2, ATPA_WELMI ;
DR   P12112, ATPA_WHEAT ;  Q8D3J5, ATPA_WIGBR ;  Q73HB2, ATPA_WOLPM ;
DR   B3CN53, ATPA_WOLPP ;  Q7MA20, ATPA_WOLSU ;  Q5GSX1, ATPA_WOLTR ;
DR   C0R2Y2, ATPA_WOLWR ;  Q8PGG5, ATPA_XANAC ;  Q3BP13, ATPA_XANC5 ;
DR   Q4UQF2, ATPA_XANC8 ;  B0RWC4, ATPA_XANCB ;  Q8PCZ7, ATPA_XANCP ;
DR   Q2P7Q6, ATPA_XANOM ;  B2SQB2, ATPA_XANOP ;  Q5H4Y6, ATPA_XANOR ;
DR   A7IH29, ATPA_XANP2 ;  B2I862, ATPA_XYLF2 ;  Q9PE83, ATPA_XYLFA ;
DR   B0U5A0, ATPA_XYLFM ;  Q87E88, ATPA_XYLFT ;  A1JTC8, ATPA_YERE8 ;
DR   A7FPE2, ATPA_YERP3 ;  Q1C093, ATPA_YERPA ;  B2K845, ATPA_YERPB ;
DR   Q8Z9S4, ATPA_YERPE ;  A9R5U1, ATPA_YERPG ;  Q1CCH3, ATPA_YERPN ;
DR   A4TSJ1, ATPA_YERPP ;  Q663Q6, ATPA_YERPS ;  B1JRN0, ATPA_YERPY ;
DR   Q32RL1, ATPA_ZYGCR ;  Q5NQZ1, ATPA_ZYMMO ;  A5E950, ATPB1_BRASB;
DR   A3MQJ9, ATPB1_BURM7;  Q62FR5, ATPB1_BURMA;  A1V8T1, ATPB1_BURMS;
DR   A3P0Z0, ATPB1_BURP0;  Q3JXV8, ATPB1_BURP1;  A3NF40, ATPB1_BURP6;
DR   Q63PI0, ATPB1_BURPS;  Q2STE9, ATPB1_BURTA;  Q13XV3, ATPB1_BURXL;
DR   Q8KDL4, ATPB1_CHLTE;  A8LN39, ATPB1_DINSH;  Q5FRC5, ATPB1_GLUOX;
DR   Q92FG8, ATPB1_LISIN;  Q724W4, ATPB1_LISMF;  Q8YAM6, ATPB1_LISMO;
DR   A0AFR1, ATPB1_LISW6;  A6VWP9, ATPB1_MARMS;  Q98QU5, ATPB1_MYCPU;
DR   Q0AJB0, ATPB1_NITEC;  Q2YCA3, ATPB1_NITMU;  Q3A605, ATPB1_PELCD;
DR   Q3B6W8, ATPB1_PELLD;  A1ALL7, ATPB1_PELPD;  Q6LLG8, ATPB1_PHOPR;
DR   A1VIV2, ATPB1_POLNA;  Q15SF7, ATPB1_PSEA6;  A1SS55, ATPB1_PSYIN;
DR   Q223D6, ATPB1_RHOFD;  A3PIB9, ATPB1_RHOS1;  Q3J431, ATPB1_RHOS4;
DR   Q07VU4, ATPB1_SHEFN;  A7N0Y1, ATPB1_VIBHB;  A5EBX1, ATPB2_BRASB;
DR   A3MAR7, ATPB2_BURM7;  Q62EB7, ATPB2_BURMA;  A1UY34, ATPB2_BURMS;
DR   A3P8M2, ATPB2_BURP0;  Q3JJN9, ATPB2_BURP1;  A3NN65, ATPB2_BURP6;
DR   Q63IW3, ATPB2_BURPS;  Q2T880, ATPB2_BURTA;  Q13SQ2, ATPB2_BURXL;
DR   Q8KAC9, ATPB2_CHLTE;  A8LJR4, ATPB2_DINSH;  Q5FNZ3, ATPB2_GLUOX;
DR   Q927W4, ATPB2_LISIN;  Q71WP9, ATPB2_LISMF;  Q8Y4C1, ATPB2_LISMO;
DR   A0ALL3, ATPB2_LISW6;  A6W3S8, ATPB2_MARMS;  Q98QB6, ATPB2_MYCPU;
DR   Q0AEJ6, ATPB2_NITEC;  Q2Y8G2, ATPB2_NITMU;  Q3A083, ATPB2_PELCD;
DR   Q3B406, ATPB2_PELLD;  A1AP52, ATPB2_PELPD;  Q6LKZ6, ATPB2_PHOPR;
DR   A1VPR5, ATPB2_POLNA;  Q15MU4, ATPB2_PSEA6;  A1T0Y9, ATPB2_PSYIN;
DR   Q21ZA6, ATPB2_RHOFD;  A3PS59, ATPB2_RHOS1;  Q3HKH4, ATPB2_RHOS4;
DR   Q07YM7, ATPB2_SHEFN;  A7N6Q5, ATPB2_VIBHB;  Q13IW3, ATPB3_BURXL;
DR   Q39ZU1, ATPB3_PELCD;  P43395, ATPBM_ACTDE;  P83483, ATPBM_ARATH;
DR   P38482, ATPBM_CHLRE;  P37399, ATPBM_DAUCA;  P29685, ATPBM_HEVBR;
DR   P19023, ATPBM_MAIZE;  P17614, ATPBM_NICPL;  Q01859, ATPBM_ORYSJ;
DR   P81663, ATPBM_PINPS;  P80083, ATPBM_SPIOL;  P85088, ATPBM_VITSX;
DR   P83484, ATPBN_ARATH;  Q9C5A9, ATPBO_ARATH;  A8ZNR6, ATPB_ACAM1 ;
DR   A9NGW2, ATPB_ACHLI ;  A1TJ41, ATPB_ACIAC ;  Q6FFK0, ATPB_ACIAD ;
DR   B7H294, ATPB_ACIB3 ;  B7I1W4, ATPB_ACIB5 ;  B2I102, ATPB_ACIBC ;
DR   Q1IIG8, ATPB_ACIBL ;  B0VNK4, ATPB_ACIBS ;  A3M144, ATPB_ACIBT ;
DR   B0VBP3, ATPB_ACIBY ;  A0LSL6, ATPB_ACIC1 ;  C1F3N6, ATPB_ACIC5 ;
DR   A5FZ54, ATPB_ACICJ ;  B9MBA3, ATPB_ACIET ;  A1W2T7, ATPB_ACISJ ;
DR   Q3V527, ATPB_ACOCL ;  Q7HDI4, ATPB_ACRAL ;  A3N2U4, ATPB_ACTP2 ;
DR   B3H2P3, ATPB_ACTP7 ;  B0BRX2, ATPB_ACTPJ ;  A6VL57, ATPB_ACTSZ ;
DR   O03062, ATPB_ADICA ;  O03064, ATPB_ADIRA ;  P62626, ATPB_AEGCO ;
DR   P62614, ATPB_AEGCR ;  A0KQX8, ATPB_AERHH ;  A4STP3, ATPB_AERS4 ;
DR   A4QJC2, ATPB_AETCO ;  A4QJK6, ATPB_AETGR ;  Q95DR6, ATPB_AGAAF ;
DR   A1EA15, ATPB_AGRST ;  Q8UC76, ATPB_AGRT5 ;  Q0VKX4, ATPB_ALCBS ;
DR   Q0A4M8, ATPB_ALHEH ;  B6EHG4, ATPB_ALISL ;  A6TK65, ATPB_ALKMQ ;
DR   A8MJV9, ATPB_ALKOO ;  B4RS81, ATPB_ALTMD ;  Q70XZ6, ATPB_AMBTC ;
DR   B3EST8, ATPB_AMOA5 ;  Q2IHQ2, ATPB_ANADE ;  A7HIX7, ATPB_ANADF ;
DR   Q5PAN2, ATPB_ANAMM ;  Q2GKK8, ATPB_ANAPZ ;  B9MS68, ATPB_ANATD ;
DR   Q3MAS0, ATPB_ANAVT ;  B0YPN7, ATPB_ANEMR ;  A2T340, ATPB_ANGEV ;
DR   P28250, ATPB_ANGLY ;  B7GMF3, ATPB_ANOFW ;  Q31794, ATPB_ANTFO ;
DR   O67828, ATPB_AQUAE ;  O50292, ATPB_AQUPY ;  A4QK25, ATPB_ARAHI ;
DR   P19366, ATPB_ARATH ;  A8EV70, ATPB_ARCB4 ;  Q9MRV8, ATPB_ARIMA ;
DR   Q5P4E2, ATPB_AROAE ;  A1R7V3, ATPB_ARTAT ;  B8HAY9, ATPB_ARTCA ;
DR   A0JY64, ATPB_ARTS2 ;  O98766, ATPB_ASACA ;  Q95AF8, ATPB_ASPEL ;
DR   O03063, ATPB_ASPND ;  Q8S8W8, ATPB_ATRBE ;  A8HS10, ATPB_AZOC5 ;
DR   B6YQC5, ATPB_AZOPC ;  A1K1S2, ATPB_AZOSB ;  A7Z9Q0, ATPB_BACA2 ;
DR   C3P1F4, ATPB_BACAA ;  C3LFH9, ATPB_BACAC ;  A0RL95, ATPB_BACAH ;
DR   Q81JZ5, ATPB_BACAN ;  B7JGN0, ATPB_BACC0 ;  Q72XE8, ATPB_BACC1 ;
DR   B7IQV8, ATPB_BACC2 ;  C1F0M8, ATPB_BACC3 ;  B7HFK1, ATPB_BACC4 ;
DR   B7HY64, ATPB_BACC7 ;  P41009, ATPB_BACCA ;  A7GV56, ATPB_BACCN ;
DR   B9IRT7, ATPB_BACCQ ;  Q814W2, ATPB_BACCR ;  Q630U3, ATPB_BACCZ ;
DR   P25075, ATPB_BACFI ;  Q5LD89, ATPB_BACFN ;  P13356, ATPB_BACFR ;
DR   Q9K6H5, ATPB_BACHD ;  Q6HAY0, ATPB_BACHK ;  Q65DX4, ATPB_BACLD ;
DR   P12698, ATPB_BACMQ ;  A8FIB2, ATPB_BACP2 ;  P07677, ATPB_BACP3 ;
DR   P22478, ATPB_BACPE ;  Q5WB78, ATPB_BACSK ;  P37809, ATPB_BACSU ;
DR   Q8A9V4, ATPB_BACTN ;  A6L4L7, ATPB_BACV8 ;  A9VSA3, ATPB_BACWK ;
DR   Q7HHX1, ATPB_BALSE ;  A1UR49, ATPB_BARBK ;  Q6G1W9, ATPB_BARHE ;
DR   Q6FYM3, ATPB_BARQU ;  Q85V24, ATPB_BARSC ;  A9IYW6, ATPB_BART1 ;
DR   A4QKB2, ATPB_BARVE ;  Q1LTV4, ATPB_BAUCH ;  Q6MGM7, ATPB_BDEBA ;
DR   Q9TMV0, ATPB_BEARE ;  Q4PLI6, ATPB_BETVU ;  B8DWS2, ATPB_BIFA0 ;
DR   A1A3C5, ATPB_BIFAA ;  B3DTV0, ATPB_BIFLD ;  Q8G7B3, ATPB_BIFLO ;
DR   B7GTZ3, ATPB_BIFLS ;  Q06J29, ATPB_BIGNA ;  O03066, ATPB_BLEOC ;
DR   Q7VQV6, ATPB_BLOFL ;  Q494C3, ATPB_BLOPB ;  Q2KU36, ATPB_BORA1 ;
DR   Q7WEM9, ATPB_BORBR ;  Q7W3B0, ATPB_BORPA ;  A9HY42, ATPB_BORPD ;
DR   Q7VU44, ATPB_BORPE ;  P00829, ATPB_BOVIN ;  Q85V57, ATPB_BOWVO ;
DR   Q89X74, ATPB_BRAJA ;  Q9MS49, ATPB_BRANA ;  P83505, ATPB_BRARA ;
DR   Q9MRR9, ATPB_BRASC ;  A4YKE0, ATPB_BRASO ;  C0Z776, ATPB_BREBN ;
DR   Q85V27, ATPB_BRIAM ;  Q2YLE6, ATPB_BRUA2 ;  Q57B88, ATPB_BRUAB ;
DR   A9M837, ATPB_BRUC2 ;  Q8YJ35, ATPB_BRUME ;  A5VSE1, ATPB_BRUO2 ;
DR   A9WWS2, ATPB_BRUSI ;  Q8FYR5, ATPB_BRUSU ;  B8D8H3, ATPB_BUCA5 ;
DR   P57124, ATPB_BUCAI ;  Q07232, ATPB_BUCAP ;  B8D6S7, ATPB_BUCAT ;
DR   Q89B39, ATPB_BUCBP ;  B1YQL4, ATPB_BURA4 ;  Q1BRB0, ATPB_BURCA ;
DR   B1JSV7, ATPB_BURCC ;  P42468, ATPB_BURCE ;  A0K2Y3, ATPB_BURCH ;
DR   B4EEY9, ATPB_BURCJ ;  Q0BJL5, ATPB_BURCM ;  A9AJG4, ATPB_BURM1 ;
DR   A2S6J8, ATPB_BURM9 ;  Q39KX6, ATPB_BURS3 ;  A4JA35, ATPB_BURVG ;
DR   A6MM43, ATPB_BUXMI ;  P46561, ATPB_CAEEL ;  Q7YJW5, ATPB_CALFG ;
DR   Q9MRQ5, ATPB_CALFL ;  A4XKX0, ATPB_CALS8 ;  Q8MBM4, ATPB_CALSE ;
DR   Q9MU82, ATPB_CALUS ;  A7ZC37, ATPB_CAMC1 ;  A7H017, ATPB_CAMC5 ;
DR   A0RR26, ATPB_CAMFF ;  A7I177, ATPB_CAMHC ;  A8FJR2, ATPB_CAMJ8 ;
DR   A7H1I1, ATPB_CAMJD ;  Q0PC30, ATPB_CAMJE ;  A1VXJ0, ATPB_CAMJJ ;
DR   Q5HX59, ATPB_CAMJR ;  B9KES3, ATPB_CAMLR ;  P99504, ATPB_CANFA ;
DR   Q9MRM0, ATPB_CANWI ;  A4QKJ9, ATPB_CAPBU ;  Q3A946, ATPB_CARHZ ;
DR   Q9MU81, ATPB_CARMI ;  B1A942, ATPB_CARPA ;  Q05FY1, ATPB_CARRP ;
DR   Q6QBP2, ATPB_CASSA ;  Q9A2V9, ATPB_CAUCR ;  B0T335, ATPB_CAUSK ;
DR   B3PIS7, ATPB_CELJU ;  P13357, ATPB_CELLY ;  A8SEB0, ATPB_CERDE ;
DR   Q8SLY2, ATPB_CHAGL ;  Q9BA96, ATPB_CHAHU ;  Q9MU80, ATPB_CHASI ;
DR   Q1ACK1, ATPB_CHAVU ;  Q5ZLC5, ATPB_CHICK ;  A9WGS4, ATPB_CHLAA ;
DR   B8G6G6, ATPB_CHLAD ;  Q19V65, ATPB_CHLAT ;  Q3AP13, ATPB_CHLCH ;
DR   B3EDQ7, ATPB_CHLL2 ;  P35110, ATPB_CHLLI ;  P42465, ATPB_CHLP8 ;
DR   B3EJK9, ATPB_CHLPB ;  A1BCJ2, ATPB_CHLPD ;  P06541, ATPB_CHLRE ;
DR   A6MMC9, ATPB_CHLSC ;  B9LBM0, ATPB_CHLSY ;  B3QUP6, ATPB_CHLT3 ;
DR   P32978, ATPB_CHLVU ;  Q1QSD0, ATPB_CHRSD ;  Q7P095, ATPB_CHRVO ;
DR   Q9MRR1, ATPB_CINCA ;  A8ACN6, ATPB_CITK8 ;  Q09MH1, ATPB_CITSI ;
DR   A5CQ60, ATPB_CLAM3 ;  B0RED4, ATPB_CLAMS ;  Q9Z687, ATPB_CLOAB ;
DR   A7FQH9, ATPB_CLOB1 ;  C3KYJ3, ATPB_CLOB6 ;  A6LQH6, ATPB_CLOB8 ;
DR   B2UZK0, ATPB_CLOBA ;  B2TK00, ATPB_CLOBB ;  A5HY52, ATPB_CLOBH ;
DR   C1FQP5, ATPB_CLOBJ ;  B1IE34, ATPB_CLOBK ;  A7G9Q9, ATPB_CLOBL ;
DR   B1KSS8, ATPB_CLOBM ;  B8I579, ATPB_CLOCE ;  Q180W5, ATPB_CLOD6 ;
DR   A5N3H7, ATPB_CLOK5 ;  A0Q2Z4, ATPB_CLONN ;  Q0TNC4, ATPB_CLOP1 ;
DR   Q8XID4, ATPB_CLOPE ;  A9KK92, ATPB_CLOPH ;  Q0SQZ5, ATPB_CLOPS ;
DR   A3DIM9, ATPB_CLOTH ;  Q7HHW4, ATPB_COCNU ;  A0A342, ATPB_COFAR ;
DR   Q48AW0, ATPB_COLP3 ;  Q8MBM3, ATPB_CONAR ;  Q9TMU1, ATPB_CONMJ ;
DR   B5Y831, ATPB_COPPD ;  C3PFR5, ATPB_CORA7 ;  Q6NHS9, ATPB_CORDI ;
DR   Q8FQ20, ATPB_COREF ;  A4QDH3, ATPB_CORGB ;  P42464, ATPB_CORGL ;
DR   Q4JUK0, ATPB_CORJK ;  C4LJL4, ATPB_CORK4 ;  B1VFY7, ATPB_CORU7 ;
DR   A9KBF7, ATPB_COXBN ;  A9NBD0, ATPB_COXBR ;  Q83AF5, ATPB_COXBU ;
DR   Q8MBK3, ATPB_CRETR ;  A4QKT8, ATPB_CRUWA ;  Q4VZI5, ATPB_CUCSA ;
DR   Q0K5M7, ATPB_CUPNH ;  Q46VY0, ATPB_CUPPJ ;  B3R7L5, ATPB_CUPTR ;
DR   A8W3D7, ATPB_CUSEX ;  Q8MBG3, ATPB_CUSGR ;  Q8MBG0, ATPB_CUSJA ;
DR   A8W3J1, ATPB_CUSOB ;  Q8MBG5, ATPB_CUSPE ;  P30399, ATPB_CUSRE ;
DR   Q8MBG4, ATPB_CUSSA ;  Q9TM41, ATPB_CYACA ;  Q85FT2, ATPB_CYAME ;
DR   B8HP55, ATPB_CYAP4 ;  B7KGV4, ATPB_CYAP7 ;  B7K2R8, ATPB_CYAP8 ;
DR   P48081, ATPB_CYAPA ;  A6H5I4, ATPB_CYCTA ;  Q9PTY0, ATPB_CYPCA ;
DR   Q11Y90, ATPB_CYTH3 ;  Q0G9V5, ATPB_DAUCA ;  Q477Z1, ATPB_DECAR ;
DR   Q3Z8Z2, ATPB_DEHE1 ;  A5FRQ5, ATPB_DEHSB ;  Q3ZZT7, ATPB_DEHSC ;
DR   A9BPU7, ATPB_DELAS ;  O03068, ATPB_DENPU ;  B8FGT4, ATPB_DESAA ;
DR   B1I6J7, ATPB_DESAP ;  B8J439, ATPB_DESDA ;  Q313W0, ATPB_DESDG ;
DR   B8FZ34, ATPB_DESHD ;  Q24MP1, ATPB_DESHY ;  A8ZUA1, ATPB_DESOH ;
DR   Q6AQ10, ATPB_DESPS ;  A4J999, ATPB_DESRM ;  Q72E04, ATPB_DESVH ;
DR   B8DRD2, ATPB_DESVM ;  A1VFJ5, ATPB_DESVV ;  O03067, ATPB_DICAN ;
DR   P30158, ATPB_DICDH ;  Q55CS9, ATPB_DICDI ;  A5EXL4, ATPB_DICNV ;
DR   B5YBP8, ATPB_DICT6 ;  B8DYT0, ATPB_DICTD ;  A6MML4, ATPB_DIOEL ;
DR   A4QL26, ATPB_DRANE ;  Q06GZ0, ATPB_DRIGR ;  Q05825, ATPB_DROME ;
DR   Q24751, ATPB_DROVI ;  A7ZTU4, ATPB_ECO24 ;  B7UMJ7, ATPB_ECO27 ;
DR   B7MGF2, ATPB_ECO45 ;  B7L882, ATPB_ECO55 ;  P0ABB6, ATPB_ECO57 ;
DR   B5YXD6, ATPB_ECO5E ;  B7NR34, ATPB_ECO7I ;  B7N2H1, ATPB_ECO81 ;
DR   B7M588, ATPB_ECO8A ;  C4ZZ10, ATPB_ECOBW ;  B1X9W0, ATPB_ECODH ;
DR   A8A6J5, ATPB_ECOHS ;  A1AHR4, ATPB_ECOK1 ;  Q0TAX7, ATPB_ECOL5 ;
DR   P0ABB5, ATPB_ECOL6 ;  B1IX06, ATPB_ECOLC ;  P0ABB4, ATPB_ECOLI ;
DR   B7NF48, ATPB_ECOLU ;  B6I3W9, ATPB_ECOSE ;  B1LL59, ATPB_ECOSM ;
DR   Q1R4K2, ATPB_ECOUT ;  C5BF40, ATPB_EDWI9 ;  Q3YS09, ATPB_EHRCJ ;
DR   Q2GGP9, ATPB_EHRCR ;  Q5FGY3, ATPB_EHRRG ;  Q5HB71, ATPB_EHRRW ;
DR   Q9BA69, ATPB_ELAOL ;  Q4G3C8, ATPB_EMIHU ;  A4WGF5, ATPB_ENT38 ;
DR   Q831A5, ATPB_ENTFA ;  P43451, ATPB_ENTHR ;  A7MMW9, ATPB_ENTS8 ;
DR   O03069, ATPB_EQUAR ;  Q6CYJ5, ATPB_ERWCT ;  B2VCA4, ATPB_ERWT9 ;
DR   Q2N8Z2, ATPB_ERYLH ;  B7LK77, ATPB_ESCF3 ;  Q85V44, ATPB_EUCBI ;
DR   Q49KZ1, ATPB_EUCGG ;  Q85V45, ATPB_EUCMO ;  P31476, ATPB_EUGGR ;
DR   O50341, ATPB_FERIS ;  A7HJV7, ATPB_FERNB ;  A5FLS1, ATPB_FLAJ1 ;
DR   A6GVV9, ATPB_FLAPJ ;  Q0RDB4, ATPB_FRAAA ;  B0TWS7, ATPB_FRAP2 ;
DR   Q2J6N3, ATPB_FRASC ;  A8L3W5, ATPB_FRASN ;  Q14K06, ATPB_FRAT1 ;
DR   A7NEH4, ATPB_FRATF ;  Q2A1I2, ATPB_FRATH ;  B2SEY1, ATPB_FRATM ;
DR   A0Q8D9, ATPB_FRATN ;  Q0BK84, ATPB_FRATO ;  Q5NIK3, ATPB_FRATT ;
DR   A4IW24, ATPB_FRATW ;  Q2PQH4, ATPB_FUCVE ;  Q8RGE2, ATPB_FUSNN ;
DR   Q9MRI8, ATPB_GALBE ;  Q08807, ATPB_GALSU ;  B5EFI7, ATPB_GEOBB ;
DR   Q5KUJ3, ATPB_GEOKA ;  B3EA01, ATPB_GEOLS ;  Q39Q56, ATPB_GEOMG ;
DR   P42006, ATPB_GEOSE ;  B9LZ84, ATPB_GEOSF ;  Q74GY0, ATPB_GEOSL ;
DR   C6E9F1, ATPB_GEOSM ;  C5D990, ATPB_GEOSW ;  Q9LA80, ATPB_GEOTH ;
DR   A4ITI9, ATPB_GEOTN ;  A5G9D8, ATPB_GEOUR ;  Q7NHG7, ATPB_GLOVI ;
DR   A9H9A8, ATPB_GLUDA ;  A6BM09, ATPB_GNEPA ;  A0ZZ42, ATPB_GOSBA ;
DR   Q2L917, ATPB_GOSHI ;  Q0BQE8, ATPB_GRABC ;  A0M791, ATPB_GRAFK ;
DR   Q6B8S4, ATPB_GRATL ;  O78491, ATPB_GUITH ;  Q7VPP0, ATPB_HAEDU ;
DR   Q4QN64, ATPB_HAEI8 ;  A5UA11, ATPB_HAEIE ;  A5UGY9, ATPB_HAEIG ;
DR   P43715, ATPB_HAEIN ;  B8F774, ATPB_HAEPS ;  Q0I5X3, ATPB_HAES1 ;
DR   B0UWG5, ATPB_HAES2 ;  Q2S6P1, ATPB_HAHCH ;  A1WZT1, ATPB_HALHL ;
DR   Q17Y78, ATPB_HELAH ;  Q1KXV2, ATPB_HELAN ;  Q7VJ21, ATPB_HELHP ;
DR   B0THN2, ATPB_HELMI ;  B6JMX2, ATPB_HELP2 ;  B5Z8D0, ATPB_HELPG ;
DR   Q1CSD5, ATPB_HELPH ;  Q9ZK81, ATPB_HELPJ ;  P55988, ATPB_HELPY ;
DR   Q25117, ATPB_HEMPU ;  A9AVV4, ATPB_HERA2 ;  A4GAG9, ATPB_HERAR ;
DR   P42466, ATPB_HERAU ;  P00828, ATPB_HORVU ;  P06576, ATPB_HUMAN ;
DR   Q5SCV8, ATPB_HUPLU ;  Q85V26, ATPB_HYANO ;  Q85V28, ATPB_HYAOR ;
DR   Q9BA84, ATPB_HYOLA ;  Q7HHY5, ATPB_HYPCO ;  O03070, ATPB_HYPHO ;
DR   Q0C100, ATPB_HYPNA ;  Q9MRF3, ATPB_IDIAU ;  Q5QZI6, ATPB_IDILO ;
DR   A6MMV1, ATPB_ILLOL ;  Q8MBQ1, ATPB_IPOAQ ;  P07137, ATPB_IPOBA ;
DR   Q8MBQ4, ATPB_IPOCC ;  Q7H8L9, ATPB_IPOOB ;  A7Y3E6, ATPB_IPOPU ;
DR   Q8MBQ3, ATPB_IPOQU ;  Q7H8M1, ATPB_IPOSE ;  Q8MBQ2, ATPB_IPOWR ;
DR   A6T470, ATPB_JANMA ;  Q28TJ6, ATPB_JANSC ;  Q06RC2, ATPB_JASNU ;
DR   A6W7G9, ATPB_KINRD ;  B5XZM4, ATPB_KLEP3 ;  A6TG36, ATPB_KLEP7 ;
DR   P49376, ATPB_KLULA ;  Q5FKY0, ATPB_LACAC ;  Q03QY8, ATPB_LACBA ;
DR   Q03A18, ATPB_LACC3 ;  Q03234, ATPB_LACCA ;  B3WDL8, ATPB_LACCB ;
DR   Q1GAW5, ATPB_LACDA ;  Q04BA3, ATPB_LACDB ;  Q042L5, ATPB_LACGA ;
DR   A8YUK1, ATPB_LACH4 ;  Q74K15, ATPB_LACJO ;  Q9CES0, ATPB_LACLA ;
DR   A2RMI2, ATPB_LACLM ;  Q02XA5, ATPB_LACLS ;  Q88UU3, ATPB_LACPL ;
DR   Q85V35, ATPB_LACPU ;  A5VIR1, ATPB_LACRD ;  B2G691, ATPB_LACRJ ;
DR   Q1WUC6, ATPB_LACS1 ;  Q332X1, ATPB_LACSA ;  Q38WK5, ATPB_LACSS ;
DR   C1D5G2, ATPB_LARHH ;  Q1MRB8, ATPB_LAWIP ;  Q5X0P3, ATPB_LEGPA ;
DR   A5III3, ATPB_LEGPC ;  Q5ZRA1, ATPB_LEGPH ;  Q5WSG8, ATPB_LEGPL ;
DR   Q6AG58, ATPB_LEIXX ;  A9L9A3, ATPB_LEMMI ;  B0SDA5, ATPB_LEPBA ;
DR   Q04S18, ATPB_LEPBJ ;  Q04ZU5, ATPB_LEPBL ;  B0SLC8, ATPB_LEPBP ;
DR   Q72SX9, ATPB_LEPIC ;  Q8F2J5, ATPB_LEPIN ;  A6YGB6, ATPB_LEPTE ;
DR   A4QLB3, ATPB_LEPVR ;  B1MW85, ATPB_LEUCK ;  Q03V29, ATPB_LEUMM ;
DR   Q7HHY7, ATPB_LICGR ;  Q9MU43, ATPB_LIRTU ;  A4QLK1, ATPB_LOBMA ;
DR   A8Y9H7, ATPB_LOLPR ;  O03073, ATPB_LONHI ;  Q9BBU0, ATPB_LOTJA ;
DR   B1HM56, ATPB_LYSSC ;  B9E8E6, ATPB_MACCJ ;  Q2VZN2, ATPB_MAGSA ;
DR   A0LDA0, ATPB_MAGSM ;  Q9MU41, ATPB_MAGTR ;  P00827, ATPB_MAIZE ;
DR   B1NWF7, ATPB_MANES ;  Q65Q07, ATPB_MANSM ;  A1U7H4, ATPB_MARAV ;
DR   Q0AKW0, ATPB_MARMM ;  P06284, ATPB_MARPO ;  Q9TKI7, ATPB_MEDSA ;
DR   Q0QEP2, ATPB_MESAU ;  Q6F202, ATPB_MESFL ;  Q11DD5, ATPB_MESSB ;
DR   Q9MUT5, ATPB_MESVI ;  Q60CR4, ATPB_METCA ;  Q1GXN0, ATPB_METFK ;
DR   A2SC70, ATPB_METPP ;  B0JFM7, ATPB_MICAN ;  O03074, ATPB_MICPL ;
DR   O03075, ATPB_MICSZ ;  Q8MBF7, ATPB_MONCA ;  Q2RFX9, ATPB_MOOTA ;
DR   Q09X10, ATPB_MORIN ;  P56480, ATPB_MOUSE ;  A0QCX8, ATPB_MYCA1 ;
DR   P63678, ATPB_MYCBO ;  A1KI98, ATPB_MYCBP ;  C1AMV4, ATPB_MYCBT ;
DR   Q2ST34, ATPB_MYCCT ;  P33253, ATPB_MYCGA ;  P47639, ATPB_MYCGE ;
DR   A4T8K2, ATPB_MYCGI ;  Q601Z5, ATPB_MYCH2 ;  Q4A8V9, ATPB_MYCH7 ;
DR   Q4AAV7, ATPB_MYCHJ ;  P45823, ATPB_MYCLE ;  B2HQK2, ATPB_MYCMM ;
DR   Q6KI82, ATPB_MYCMO ;  Q6MS94, ATPB_MYCMS ;  Q73X59, ATPB_MYCPA ;
DR   Q8EWY8, ATPB_MYCPE ;  Q50331, ATPB_MYCPN ;  A0R200, ATPB_MYCS2 ;
DR   Q4A604, ATPB_MYCS5 ;  A3Q3B1, ATPB_MYCSJ ;  A1UJY4, ATPB_MYCSK ;
DR   Q1B553, ATPB_MYCSS ;  A5U209, ATPB_MYCTA ;  P63677, ATPB_MYCTU ;
DR   A0PUK0, ATPB_MYCUA ;  A1TD55, ATPB_MYCVP ;  Q9MU30, ATPB_MYRFG ;
DR   Q1CX36, ATPB_MYXXD ;  Q09FV4, ATPB_NANDO ;  A4QLU0, ATPB_NASOF ;
DR   B9L7Y7, ATPB_NAUPA ;  Q5F4Z0, ATPB_NEIG1 ;  B4RJG0, ATPB_NEIG2 ;
DR   A9M123, ATPB_NEIM0 ;  Q9JW70, ATPB_NEIMA ;  Q9JXQ2, ATPB_NEIMB ;
DR   A1KW11, ATPB_NEIMF ;  Q2GD08, ATPB_NEOSM ;  Q9TL34, ATPB_NEPOL ;
DR   P23704, ATPB_NEUCR ;  P69369, ATPB_NICBI ;  P69370, ATPB_NICPL ;
DR   P26530, ATPB_NICRU ;  P26531, ATPB_NICSP ;  Q3C1J5, ATPB_NICSY ;
DR   Q33C27, ATPB_NICTO ;  Q82XP8, ATPB_NITEU ;  Q1QQS8, ATPB_NITHX ;
DR   Q3J6N1, ATPB_NITOC ;  A6Q4C0, ATPB_NITSB ;  Q3SVJ1, ATPB_NITWN ;
DR   Q5Z0Y1, ATPB_NOCFA ;  A1SHJ1, ATPB_NOCSJ ;  B2IUL2, ATPB_NOSP7 ;
DR   P06540, ATPB_NOSS1 ;  Q2G5N5, ATPB_NOVAD ;  Q6EW72, ATPB_NYMAL ;
DR   Q9MU26, ATPB_NYMOD ;  Q9BA85, ATPB_NYPFR ;  Q8EM83, ATPB_OCEIH ;
DR   A6WXX1, ATPB_OCHA4 ;  Q40612, ATPB_OCHNE ;  P49647, ATPB_ODOSI ;
DR   B0Z4L0, ATPB_OENAR ;  B0Z4U4, ATPB_OENBI ;  Q9MTP7, ATPB_OENEH ;
DR   B0Z528, ATPB_OENGL ;  Q04G20, ATPB_OENOB ;  B0Z5B2, ATPB_OENPA ;
DR   B6JD09, ATPB_OLICO ;  A4QJU0, ATPB_OLIPU ;  Q20EW8, ATPB_OLTVI ;
DR   A5CDA5, ATPB_ORITB ;  B3CRK6, ATPB_ORITI ;  Q9TMQ4, ATPB_ORNLO ;
DR   Q6ENG7, ATPB_ORYNI ;  P0C2Z7, ATPB_ORYSA ;  P0C2Z8, ATPB_ORYSI ;
DR   P12085, ATPB_ORYSJ ;  O03077, ATPB_OSMCI ;  Q0P3P2, ATPB_OSTTA ;
DR   Q85V29, ATPB_OTHSI ;  Q68RZ9, ATPB_PANGI ;  A6L8P2, ATPB_PARD8 ;
DR   A1B8P0, ATPB_PARDP ;  A7HT52, ATPB_PARL1 ;  Q6MAK7, ATPB_PARUW ;
DR   Q9CKW1, ATPB_PASMU ;  P05037, ATPB_PEA   ;  C6DJH2, ATPB_PECCP ;
DR   Q03235, ATPB_PECFR ;  Q03EL4, ATPB_PEDPA ;  Q06FV3, ATPB_PELHO ;
DR   B4SAN6, ATPB_PELPB ;  A5CYE2, ATPB_PELTS ;  Q4FP38, ATPB_PELUB ;
DR   P85446, ATPB_PENGL ;  P42467, ATPB_PEPNI ;  A9BFX3, ATPB_PETMO ;
DR   Q3BAN5, ATPB_PHAAO ;  A0T0D2, ATPB_PHATC ;  A4GG90, ATPB_PHAVU ;
DR   Q9BA86, ATPB_PHODC ;  Q7NA94, ATPB_PHOLL ;  Q95AD7, ATPB_PHOTN ;
DR   P80658, ATPB_PHYPA ;  O47037, ATPB_PICAB ;  Q85X24, ATPB_PINKO ;
DR   P41622, ATPB_PINTH ;  Q06GQ3, ATPB_PIPCE ;  Q09G39, ATPB_PLAOC ;
DR   B1XSD4, ATPB_POLNS ;  Q12GQ0, ATPB_POLSJ ;  A4SUT4, ATPB_POLSQ ;
DR   Q14FF0, ATPB_POPAL ;  Q95FL8, ATPB_POPTM ;  A4GYR7, ATPB_POPTR ;
DR   P51259, ATPB_PORPU ;  Q1XDM8, ATPB_PORYE ;  Q6A8C7, ATPB_PROAC ;
DR   P50003, ATPB_PRODI ;  A3PES6, ATPB_PROM0 ;  A2C4I4, ATPB_PROM1 ;
DR   A8G6T8, ATPB_PROM2 ;  A2C6Z4, ATPB_PROM3 ;  A9BCC6, ATPB_PROM4 ;
DR   A2BYG3, ATPB_PROM5 ;  Q318V4, ATPB_PROM9 ;  Q7VA76, ATPB_PROMA ;
DR   B4F0E7, ATPB_PROMH ;  Q7V5U2, ATPB_PROMM ;  Q7V049, ATPB_PROMP ;
DR   A2BT12, ATPB_PROMS ;  Q46J68, ATPB_PROMT ;  A4SC45, ATPB_PROVI ;
DR   Q9TJR9, ATPB_PROWI ;  Q48BG5, ATPB_PSE14 ;  A6VF32, ATPB_PSEA7 ;
DR   B7V791, ATPB_PSEA8 ;  Q02DF4, ATPB_PSEAB ;  Q9HT20, ATPB_PSEAE ;
DR   Q3ZJ68, ATPB_PSEAK ;  Q85V50, ATPB_PSECV ;  Q1I2I7, ATPB_PSEE4 ;
DR   Q4K3A9, ATPB_PSEF5 ;  C3K1E6, ATPB_PSEFS ;  Q3IK50, ATPB_PSEHT ;
DR   A4Y187, ATPB_PSEMY ;  A5WBA3, ATPB_PSEP1 ;  Q3K441, ATPB_PSEPF ;
DR   B0KRA8, ATPB_PSEPG ;  Q88BX4, ATPB_PSEPK ;  B1JFU1, ATPB_PSEPW ;
DR   Q87TT4, ATPB_PSESM ;  Q4ZL24, ATPB_PSEU2 ;  A4VS62, ATPB_PSEU5 ;
DR   O03081, ATPB_PSINU ;  Q4FQ37, ATPB_PSYA2 ;  Q1Q899, ATPB_PSYCK ;
DR   A5WBW1, ATPB_PSYWF ;  O03079, ATPB_PTEAQ ;  O03080, ATPB_PTEES ;
DR   P26532, ATPB_PYLLI ;  Q1LHL0, ATPB_RALME ;  Q8XU76, ATPB_RALSO ;
DR   Q9MTG8, ATPB_RAPSA ;  P10719, ATPB_RAT   ;  A9WNC8, ATPB_RENSM ;
DR   A6MVY0, ATPB_RHDSA ;  B3PQ68, ATPB_RHIE6 ;  Q2K3H0, ATPB_RHIEC ;
DR   Q1MAZ2, ATPB_RHIL3 ;  Q98EV8, ATPB_RHILO ;  B5ZSN7, ATPB_RHILW ;
DR   Q92LK8, ATPB_RHIME ;  C3M9S1, ATPB_RHISN ;  Q7UFB5, ATPB_RHOBA ;
DR   P05440, ATPB_RHOBL ;  P72247, ATPB_RHOCA ;  C1A1X8, ATPB_RHOE4 ;
DR   C1AVZ9, ATPB_RHOOB ;  Q2J3I4, ATPB_RHOP2 ;  Q07UZ5, ATPB_RHOP5 ;
DR   Q6NDD2, ATPB_RHOPA ;  Q21CY7, ATPB_RHOPB ;  Q13DP2, ATPB_RHOPS ;
DR   Q2RV18, ATPB_RHORT ;  P05038, ATPB_RHORU ;  A4WUM7, ATPB_RHOS5 ;
DR   Q0SGP9, ATPB_RHOSR ;  C3PLT1, ATPB_RICAE ;  A8GPZ4, ATPB_RICAH ;
DR   A8GY40, ATPB_RICB8 ;  Q1RKD7, ATPB_RICBR ;  A8F004, ATPB_RICCK ;
DR   Q92G88, ATPB_RICCN ;  Q4UK18, ATPB_RICFE ;  A8F2U0, ATPB_RICM5 ;
DR   O50290, ATPB_RICPR ;  C4K227, ATPB_RICPU ;  B0BVB6, ATPB_RICRO ;
DR   A8GTS6, ATPB_RICRS ;  Q68VU8, ATPB_RICTY ;  A7NIQ9, ATPB_ROSCS ;
DR   Q162S9, ATPB_ROSDO ;  A5UQN3, ATPB_ROSS1 ;  Q7HHX4, ATPB_ROYRE ;
DR   Q1AVH9, ATPB_RUBXD ;  A1AXU2, ATPB_RUTMC ;  Q21DK8, ATPB_SACD2 ;
DR   Q6L392, ATPB_SACHY ;  Q6ENV6, ATPB_SACOF ;  B5EYZ6, ATPB_SALA4 ;
DR   A8M2J3, ATPB_SALAI ;  A9MJR9, ATPB_SALAR ;  Q57HX9, ATPB_SALCH ;
DR   B5FN33, ATPB_SALDC ;  B5QUS4, ATPB_SALEP ;  B5RFW3, ATPB_SALG2 ;
DR   B4TAX2, ATPB_SALHS ;  B4SYD1, ATPB_SALNS ;  Q5PKX2, ATPB_SALPA ;
DR   A9MXA6, ATPB_SALPB ;  C0Q2N2, ATPB_SALPC ;  B5BIN6, ATPB_SALPK ;
DR   Q2RZV3, ATPB_SALRD ;  B4TN31, ATPB_SALSV ;  Q8XGX4, ATPB_SALTI ;
DR   A4XAW2, ATPB_SALTO ;  Q7CPE2, ATPB_SALTY ;  Q7HHY4, ATPB_SALZA ;
DR   Q9MTY2, ATPB_SARHE ;  Q1KVT0, ATPB_SCEOB ;  Q07233, ATPB_SCHGA ;
DR   Q85V31, ATPB_SCHME ;  P22068, ATPB_SCHPO ;  Q9MTX9, ATPB_SCHSP ;
DR   A8G7M8, ATPB_SERP5 ;  A1SBU0, ATPB_SHEAM ;  B8EDV0, ATPB_SHEB2 ;
DR   A3DAR4, ATPB_SHEB5 ;  A6WUJ0, ATPB_SHEB8 ;  A9KX06, ATPB_SHEB9 ;
DR   Q12HQ1, ATPB_SHEDO ;  B0TQF4, ATPB_SHEHH ;  A3QJR0, ATPB_SHELP ;
DR   Q8E8C0, ATPB_SHEON ;  A8HAG3, ATPB_SHEPA ;  A4YCH8, ATPB_SHEPC ;
DR   B8CVU5, ATPB_SHEPW ;  A0L2S8, ATPB_SHESA ;  A8G1W5, ATPB_SHESH ;
DR   Q0HD79, ATPB_SHESM ;  Q0HPG1, ATPB_SHESR ;  A1RQB0, ATPB_SHESW ;
DR   B1KQ34, ATPB_SHEWM ;  B2TUP3, ATPB_SHIB3 ;  Q31UN2, ATPB_SHIBS ;
DR   Q329S1, ATPB_SHIDS ;  Q0SYU4, ATPB_SHIF8 ;  P0ABB7, ATPB_SHIFL ;
DR   Q3YVN6, ATPB_SHISS ;  Q5LNP1, ATPB_SILPO ;  Q1GEU8, ATPB_SILST ;
DR   A6UDM1, ATPB_SINMW ;  Q2NQ86, ATPB_SODGM ;  Q2MII0, ATPB_SOLBU ;
DR   Q2MI93, ATPB_SOLLC ;  Q2VEH0, ATPB_SOLTU ;  Q02BU1, ATPB_SOLUE ;
DR   A1E9T1, ATPB_SORBI ;  A9F3R4, ATPB_SORC5 ;  Q2PMV0, ATPB_SOYBN ;
DR   Q1GQS5, ATPB_SPHAL ;  A5V3X5, ATPB_SPHWW ;  P00825, ATPB_SPIOL ;
DR   A7X4U3, ATPB_STAA1 ;  A6U3I8, ATPB_STAA2 ;  Q2FF24, ATPB_STAA3 ;
DR   Q2FWF0, ATPB_STAA8 ;  A5IUP8, ATPB_STAA9 ;  Q2YUK1, ATPB_STAAB ;
DR   Q5HE97, ATPB_STAAC ;  A6QIU7, ATPB_STAAE ;  P63679, ATPB_STAAM ;
DR   P99112, ATPB_STAAN ;  Q6GEX2, ATPB_STAAR ;  Q6G7K7, ATPB_STAAS ;
DR   A8YY70, ATPB_STAAT ;  P63680, ATPB_STAAW ;  B9DME3, ATPB_STACT ;
DR   Q5HMB9, ATPB_STAEQ ;  Q8CNJ7, ATPB_STAES ;  Q4L7Y4, ATPB_STAHJ ;
DR   Q32RY8, ATPB_STAPU ;  Q49Z50, ATPB_STAS1 ;  P42469, ATPB_STIAU ;
DR   Q06SG7, ATPB_STIHE ;  Q3K1J5, ATPB_STRA1 ;  Q8E5U8, ATPB_STRA3 ;
DR   Q8E072, ATPB_STRA5 ;  Q82J84, ATPB_STRAW ;  P0A300, ATPB_STRCO ;
DR   P21933, ATPB_STRDO ;  C0M720, ATPB_STRE4 ;  B4U2E1, ATPB_STREM ;
DR   A8AYG1, ATPB_STRGC ;  B1W0A3, ATPB_STRGG ;  P0A301, ATPB_STRLI ;
DR   B4SJR9, ATPB_STRM5 ;  B2FHY8, ATPB_STRMK ;  P95789, ATPB_STRMU ;
DR   Q9A0I7, ATPB_STRP1 ;  Q04HT9, ATPB_STRP2 ;  P0DA04, ATPB_STRP3 ;
DR   B5E670, ATPB_STRP4 ;  Q5XCY0, ATPB_STRP6 ;  C1C899, ATPB_STRP7 ;
DR   Q8P1K5, ATPB_STRP8 ;  Q1JCL3, ATPB_STRPB ;  Q1JMI9, ATPB_STRPC ;
DR   Q1JHN5, ATPB_STRPD ;  Q1J7F9, ATPB_STRPF ;  A2RFC2, ATPB_STRPG ;
DR   B1ICS9, ATPB_STRPI ;  B8ZLA9, ATPB_STRPJ ;  Q48UD3, ATPB_STRPM ;
DR   Q97PT6, ATPB_STRPN ;  P0DA05, ATPB_STRPQ ;  B2IQX0, ATPB_STRPS ;
DR   B5XKQ1, ATPB_STRPZ ;  Q8DP44, ATPB_STRR6 ;  A4W1V7, ATPB_STRS2 ;
DR   C0MH17, ATPB_STRS7 ;  A3CM14, ATPB_STRSV ;  A4VVJ9, ATPB_STRSY ;
DR   Q5M104, ATPB_STRT1 ;  Q5M5J1, ATPB_STRT2 ;  Q03LX3, ATPB_STRTD ;
DR   B9DRT6, ATPB_STRU0 ;  C1CF93, ATPB_STRZJ ;  C1CLK6, ATPB_STRZP ;
DR   C1CSC8, ATPB_STRZT ;  Q30QQ1, ATPB_SULDN ;  A8Z6C7, ATPB_SULMW ;
DR   A6QB59, ATPB_SULNB ;  Q67TB7, ATPB_SYMTH ;  Q2LR05, ATPB_SYNAS ;
DR   Q31KS4, ATPB_SYNE7 ;  A0LLF8, ATPB_SYNFM ;  Q2JX57, ATPB_SYNJA ;
DR   Q2JIV9, ATPB_SYNJB ;  Q05373, ATPB_SYNP1 ;  P07890, ATPB_SYNP6 ;
DR   A5GNB1, ATPB_SYNPW ;  Q7U8U7, ATPB_SYNPX ;  A5GV55, ATPB_SYNR3 ;
DR   Q0I7U1, ATPB_SYNS3 ;  Q3AZK5, ATPB_SYNS9 ;  Q3AHM2, ATPB_SYNSC ;
DR   Q0AUD3, ATPB_SYNWW ;  P26527, ATPB_SYNY3 ;  C5BKJ5, ATPB_TERTT ;
DR   A0T0R6, ATPB_THAPS ;  B7IG44, ATPB_THEAB ;  Q8DLG8, ATPB_THEEB ;
DR   Q47M82, ATPB_THEFY ;  A8F3K2, ATPB_THELT ;  A6LJR1, ATPB_THEM4 ;
DR   O50550, ATPB_THEMA ;  B9K7U1, ATPB_THENN ;  A5ILX2, ATPB_THEP1 ;
DR   B1LBB9, ATPB_THESQ ;  Q8RC15, ATPB_THETN ;  B5YI24, ATPB_THEYD ;
DR   Q31DM0, ATPB_THICR ;  Q3SF66, ATPB_THIDA ;  P41168, ATPB_THIFE ;
DR   B8GRB8, ATPB_THISH ;  P00826, ATPB_TOBAC ;  C4LDW0, ATPB_TOLAT ;
DR   Q9BA92, ATPB_TRAFO ;  Q10Z38, ATPB_TRIEI ;  Q9XQX2, ATPB_TROAR ;
DR   Q83HY0, ATPB_TROW8 ;  Q83G91, ATPB_TROWT ;  B1AIB8, ATPB_UREP2 ;
DR   Q9PR15, ATPB_UREPA ;  B5ZAW1, ATPB_UREU1 ;  O03085, ATPB_VANDA ;
DR   A1WF58, ATPB_VEREI ;  A5CVI6, ATPB_VESOH ;  P12986, ATPB_VIBAL ;
DR   A5F459, ATPB_VIBC3 ;  Q9KNH5, ATPB_VIBCH ;  C3LSI9, ATPB_VIBCM ;
DR   Q5E1N7, ATPB_VIBF1 ;  B5FCZ1, ATPB_VIBFM ;  Q87KA8, ATPB_VIBPA ;
DR   Q8DDG8, ATPB_VIBVU ;  Q7MGI0, ATPB_VIBVY ;  Q0ZJ13, ATPB_VITVI ;
DR   P20858, ATPB_WHEAT ;  Q95AD6, ATPB_WHIBI ;  Q8D3J3, ATPB_WIGBR ;
DR   Q73IG3, ATPB_WOLPM ;  B3CN17, ATPB_WOLPP ;  P42470, ATPB_WOLSU ;
DR   Q5GRU7, ATPB_WOLTR ;  C0R5I6, ATPB_WOLWR ;  Q8PGG7, ATPB_XANAC ;
DR   Q3BP15, ATPB_XANC5 ;  Q4UQF4, ATPB_XANC8 ;  B0RWC2, ATPB_XANCB ;
DR   Q8PCZ5, ATPB_XANCP ;  Q2P7Q4, ATPB_XANOM ;  B2SQB0, ATPB_XANOP ;
DR   Q5H4Y4, ATPB_XANOR ;  A7IH31, ATPB_XANP2 ;  B2I877, ATPB_XYLF2 ;
DR   Q9PE85, ATPB_XYLFA ;  B0U598, ATPB_XYLFM ;  Q87E90, ATPB_XYLFT ;
DR   P00830, ATPB_YEAST ;  A1JTC6, ATPB_YERE8 ;  A7FPE0, ATPB_YERP3 ;
DR   Q1C095, ATPB_YERPA ;  B2K847, ATPB_YERPB ;  Q7CFM8, ATPB_YERPE ;
DR   A9R5T9, ATPB_YERPG ;  Q1CCH5, ATPB_YERPN ;  A4TSJ3, ATPB_YERPP ;
DR   Q663Q8, ATPB_YERPS ;  B1JRN2, ATPB_YERPY ;  Q32RI0, ATPB_ZYGCR ;
DR   Q5NQY9, ATPB_ZYMMO ;  O34171, FLII_AGRT5 ;  O67531, FLII_AQUAE ;
DR   P23445, FLII_BACSU ;  P52607, FLII_BORBU ;  P57178, FLII_BUCAI ;
DR   Q8KA42, FLII_BUCAP ;  Q89AZ7, FLII_BUCBP ;  B8H363, FLII_CAUCN ;
DR   P0CAT8, FLII_CAUCR ;  P52612, FLII_ECOLI ;  Q9ZJJ3, FLII_HELPJ ;
DR   O07025, FLII_HELPY ;  Q9I4N1, FLII_PSEAE ;  O54249, FLII_RHIME ;
DR   P26465, FLII_SALTY ;  O83417, FLII_TREPA ;  Q8RK01, HRCN_PSESH ;
DR   Q887B5, HRCN_PSESM ;  Q52371, HRCN_PSESY ;  P80153, HRPB6_XANEU;
DR   Q4J8L6, MTPE_SULAC ;  P62019, MTPE_SULTO ;  P43440, NTPJ_ENTHR ;
DR   P0A1C0, SPAL_SALTI ;  P0A1B9, SPAL_SALTY ;  P0A1C1, SPAL_SHIFL ;
DR   P0A1C2, SPAL_SHISO ;  P74857, SSAN_SALTY ;  Q38676, VATA1_ACEAT;
DR   Q896K4, VATA1_CLOTE;  P48602, VATA1_DROME;  Q04236, VATA1_EQUAR;
DR   Q2FP52, VATA1_METHJ;  Q04237, VATA1_PSINU;  O83441, VATA1_TREPA;
DR   Q38677, VATA2_ACEAT;  Q891P1, VATA2_CLOTE;  Q27331, VATA2_DROME;
DR   Q04238, VATA2_EQUAR;  Q2FL43, VATA2_METHJ;  Q04239, VATA2_PSINU;
DR   O83541, VATA2_TREPA;  Q2FQE9, VATA3_METHJ;  O16109, VATA_AEDAE ;
DR   Q2TJ56, VATA_AEDAL ;  Q9YF35, VATA_AERPE ;  B8JE35, VATA_ANAD2 ;
DR   Q2IQ95, VATA_ANADE ;  A7HDG9, VATA_ANADF ;  B4UH39, VATA_ANASK ;
DR   Q5TTG1, VATA_ANOGA ;  O23654, VATA_ARATH ;  O29101, VATA_ARCFU ;
DR   Q9UVJ8, VATA_ASHGO ;  Q39442, VATA_BETVU ;  Q0SP70, VATA_BORAP ;
DR   O51121, VATA_BORBU ;  B7J127, VATA_BORBZ ;  B5RLG8, VATA_BORDL ;
DR   Q662R8, VATA_BORGA ;  B2S1S8, VATA_BORHD ;  B5RQS2, VATA_BORRA ;
DR   A1QYP3, VATA_BORT9 ;  P31404, VATA_BOVIN ;  Q39291, VATA_BRANA ;
DR   Q61VZ4, VATA_CAEBR ;  Q9XW92, VATA_CAEEL ;  P38078, VATA_CANTR ;
DR   A0RXK1, VATA_CENSY ;  Q90647, VATA_CHICK ;  Q5L5J0, VATA_CHLAB ;
DR   Q822J8, VATA_CHLCV ;  Q9PK85, VATA_CHLMU ;  Q9Z993, VATA_CHLPN ;
DR   B0B7M4, VATA_CHLT2 ;  Q3KM54, VATA_CHLTA ;  B0BBT9, VATA_CHLTB ;
DR   O84310, VATA_CHLTR ;  Q9SM09, VATA_CITUN ;  A7FWQ7, VATA_CLOB1 ;
DR   B2UWY4, VATA_CLOBA ;  B2TP91, VATA_CLOBB ;  A5I557, VATA_CLOBH ;
DR   B1IJM8, VATA_CLOBK ;  A7GGL4, VATA_CLOBL ;  B1KXT6, VATA_CLOBM ;
DR   Q184E7, VATA_CLOD6 ;  A0PZC6, VATA_CLONN ;  Q0TPW7, VATA_CLOP1 ;
DR   Q8XJW5, VATA_CLOPE ;  Q0SSI2, VATA_CLOPS ;  A3DHP0, VATA_CLOTH ;
DR   P48414, VATA_CYACA ;  P09469, VATA_DAUCA ;  C1CXU3, VATA_DEIDV ;
DR   Q1IWP3, VATA_DEIGD ;  Q9RWG8, VATA_DEIRA ;  O06504, VATA_DESSY ;
DR   P54647, VATA_DICDI ;  Q8SQU9, VATA_ENCCU ;  Q834X9, VATA_ENTFA ;
DR   P31405, VATA_GOSHI ;  Q5UXY8, VATA_HALMA ;  B8CZG8, VATA_HALOH ;
DR   B0R755, VATA_HALS3 ;  Q9HNE3, VATA_HALSA ;  Q48332, VATA_HALVD ;
DR   Q18FB7, VATA_HALWD ;  Q40002, VATA_HORVU ;  P38606, VATA_HUMAN ;
DR   A2BKX6, VATA_HYPBU ;  A8AC29, VATA_IGNH4 ;  P49087, VATA_MAIZE ;
DR   P31400, VATA_MANSE ;  P86205, VATA_MESAU ;  A6UT35, VATA_META3 ;
DR   Q8TIJ1, VATA_METAC ;  A7IAU8, VATA_METB6 ;  P22662, VATA_METBA ;
DR   Q46FH3, VATA_METBF ;  Q12WL1, VATA_METBU ;  Q57670, VATA_METJA ;
DR   Q8TWL6, VATA_METKA ;  A2SST5, VATA_METLZ ;  A4FXD4, VATA_METM5 ;
DR   A9AAQ4, VATA_METM6 ;  A6VFZ2, VATA_METM7 ;  Q60186, VATA_METMA ;
DR   A3CS71, VATA_METMJ ;  Q6LYE7, VATA_METMP ;  A5UKB2, VATA_METS3 ;
DR   A4YI05, VATA_METS5 ;  Q2NF87, VATA_METST ;  O27036, VATA_METTH ;
DR   A0B9K2, VATA_METTP ;  A6UP54, VATA_METVS ;  P50516, VATA_MOUSE ;
DR   Q74MJ7, VATA_NANEQ ;  Q3ITC8, VATA_NATPD ;  P11592, VATA_NEUCR ;
DR   A9A2R0, VATA_NITMS ;  Q3J9F3, VATA_NITOC ;  Q6MAJ5, VATA_PARUW ;
DR   Q29048, VATA_PIG   ;  Q76NM6, VATA_PLAF7 ;  Q03498, VATA_PLAFA ;
DR   Q5R5H2, VATA_PONAB ;  Q9UXU7, VATA_PYRAB ;  Q8ZYR1, VATA_PYRAE ;
DR   A4WN96, VATA_PYRAR ;  A3MXY7, VATA_PYRCJ ;  Q8U4A6, VATA_PYRFU ;
DR   O57728, VATA_PYRHO ;  A1RSF1, VATA_PYRIL ;  Q5JIR3, VATA_PYRKO ;
DR   P31406, VATA_SCHPO ;  A3DNQ6, VATA_STAMF ;  A8AUJ7, VATA_STRGC ;
DR   Q9A1Q3, VATA_STRP1 ;  P0DA06, VATA_STRP3 ;  B5E552, VATA_STRP4 ;
DR   Q5XE50, VATA_STRP6 ;  Q8P2U6, VATA_STRP8 ;  Q1JDX0, VATA_STRPB ;
DR   Q1JNS8, VATA_STRPC ;  Q1JIX5, VATA_STRPD ;  Q1J8S5, VATA_STRPF ;
DR   A2RC97, VATA_STRPG ;  B1ICC9, VATA_STRPI ;  B8ZK31, VATA_STRPJ ;
DR   Q48VL3, VATA_STRPM ;  Q97QA8, VATA_STRPN ;  P0DA07, VATA_STRPQ ;
DR   B5XJH3, VATA_STRPZ ;  A3CK48, VATA_STRSV ;  C1CES2, VATA_STRZJ ;
DR   Q4J8L9, VATA_SULAC ;  C3N6D5, VATA_SULIA ;  C4KHV0, VATA_SULIK ;
DR   C3MQL5, VATA_SULIL ;  C3MW93, VATA_SULIM ;  C3NGV1, VATA_SULIN ;
DR   C3NEU3, VATA_SULIY ;  Q9UWW6, VATA_SULSO ;  Q971B7, VATA_SULTO ;
DR   Q9P997, VATA_THEAC ;  C5A336, VATA_THEGJ ;  B1YC22, VATA_THENV ;
DR   B6YV14, VATA_THEON ;  B0K8E8, VATA_THEP3 ;  A1RX21, VATA_THEPD ;
DR   B0K5J0, VATA_THEPX ;  O32466, VATA_THESI ;  C6A5E8, VATA_THESM ;
DR   Q72J72, VATA_THET2 ;  Q56403, VATA_THET8 ;  Q97CQ0, VATA_THEVO ;
DR   Q73M28, VATA_TREDE ;  Q26975, VATA_TRYCO ;  Q0W363, VATA_UNCMA ;
DR   P13548, VATA_VIGRR ;  P17255, VATA_YEAST ;  P55717, Y4YI_RHISN ;
DR   P93303, YMF19_ARATH;  Q03152, YMF19_BRANA;  P41248, YMF19_HELAN;
DR   P38462, YMF19_MARPO;  P08746, YMF19_OENBE;  Q06564, YMF19_RAPSA;
DR   P43650, YMF19_WHEAT;  P40290, YSCN_YEREN ;  P40291, YSCN_YERPS ;
//
ID   3.6.3.15
DE   Sodium-transporting two-sector ATPase.
AN   ATP synthase, sodium ion specific.
AN   Na(+)-translocating ATPase.
AN   Na(+)-transporting two-sector ATPase.
CA   ATP + H(2)O + Na(+)(In) = ADP + phosphate + Na(+)(Out).
CC   -!- A multisubunit non-phosphorylated ATPase that is involved in the
CC       transport of ions.
CC   -!- An enzyme found in alkaliphilic bacteria that is similar to
CC       EC 3.6.3.14.
PR   PROSITE; PDOC00137;
PR   PROSITE; PDOC00138;
PR   PROSITE; PDOC00327;
PR   PROSITE; PDOC00420;
PR   PROSITE; PDOC00526;
DR   P50000, ATPA_ACEWO ;  P29706, ATPA_PROMO ;  P50002, ATPB_ACEWO ;
DR   P29707, ATPB_PROMO ;  Q08636, NTPA_ENTHR ;
//
ID   3.6.3.16
DE   Arsenite-transporting ATPase.
AN   Arsenical pump-driving ATPase.
AN   Arsenical resistance ATPase.
AN   Arsenite-translocating ATPase.
CA   ATP + H(2)O + arsenite(In) = ADP + phosphate + arsenite(Out).
CC   -!- A bacterial multisubunit non-phosphorylated ATPase that is involved
CC       in the export of arsenite and antimonite anions.
DR   O66908, ARSA1_AQUAE;  P08690, ARSA1_ECOLX;  O66674, ARSA2_AQUAE;
DR   P52145, ARSA2_ECOLX;  O50593, ARSA_ACIMA ;  Q46366, ARSA_CHLTE ;
DR   Q46465, ARSA_CHLVI ;  O52027, ARSA_HALSA ;  Q58542, ARSA_METJA ;
DR   O27555, ARSA_METTH ;  Q55794, ARSA_SYNY3 ;
//
ID   3.6.3.17
DE   Monosaccharide-transporting ATPase.
CA   ATP + H(2)O + monosaccharide(Out) = ADP + phosphate + monosaccharide(In).
CC   -!- Family of bacterial enzymes importing ribose, xylose, arabinose,
CC       galactose and methylgalactoside.
PR   PROSITE; PDOC00185;
DR   P32721, ALSA_ECOLI ;  Q1BZA2, ARAG1_BURCA;  A0K4E8, ARAG1_BURCH;
DR   Q0BIE1, ARAG1_BURCM;  Q39JR1, ARAG1_BURS3;  Q2SZC2, ARAG1_BURTA;
DR   Q1BJW2, ARAG2_BURCA;  A0B3Z7, ARAG2_BURCH;  Q0B5V4, ARAG2_BURCM;
DR   Q39BJ8, ARAG2_BURS3;  Q2T4S8, ARAG2_BURTA;  Q1JUP7, ARAG_AZOBR ;
DR   Q9K7C3, ARAG_BACHD ;  Q62GY9, ARAG_BURMA ;  Q3JNJ9, ARAG_BURP1 ;
DR   Q63QQ7, ARAG_BURPS ;  Q13U53, ARAG_BURXL ;  Q1QYT1, ARAG_CHRSD ;
DR   P0AAF5, ARAG_ECO57 ;  Q0TGT7, ARAG_ECOL5 ;  P0AAF4, ARAG_ECOL6 ;
DR   P0AAF3, ARAG_ECOLI ;  Q1RAN8, ARAG_ECOUT ;  Q6D4W8, ARAG_ERWCT ;
DR   Q9S472, ARAG_GEOSE ;  Q65WJ1, ARAG_MANSM ;  Q48IS7, ARAG_PSE14 ;
DR   Q3K8M7, ARAG_PSEPF ;  Q882I8, ARAG_PSESM ;  Q4ZTW1, ARAG_PSEU2 ;
DR   Q8XVS2, ARAG_RALSO ;  Q2K3Y7, ARAG_RHIEC ;  Q1MBG4, ARAG_RHIL3 ;
DR   Q92W56, ARAG_RHIME ;  Q322L1, ARAG_SHIBS ;  Q32HC7, ARAG_SHIDS ;
DR   Q83KP2, ARAG_SHIFL ;  Q3Z2S7, ARAG_SHISS ;  Q87FK7, ARAG_VIBPA ;
DR   Q1C7J0, ARAG_YERPA ;  Q0WER5, ARAG_YERPE ;  Q1CIX6, ARAG_YERPN ;
DR   Q66AF5, ARAG_YERPS ;  Q6LK34, MGLA1_PHOPR;  Q6LG59, MGLA2_PHOPR;
DR   Q0TQU8, MGLA_CLOP1 ;  Q8XKQ2, MGLA_CLOPE ;  Q0ST95, MGLA_CLOPS ;
DR   Q896Y2, MGLA_CLOTE ;  Q8X5D9, MGLA_ECO57 ;  Q0TFU2, MGLA_ECOL5 ;
DR   Q8FFU7, MGLA_ECOL6 ;  P0AAG8, MGLA_ECOLI ;  Q1R9S4, MGLA_ECOUT ;
DR   Q8REE1, MGLA_FUSNN ;  Q4QM77, MGLA_HAEI8 ;  P44884, MGLA_HAEIN ;
DR   Q65UW1, MGLA_MANSM ;  Q9CM08, MGLA_PASMU ;  P23924, MGLA_SALTY ;
DR   Q31YV7, MGLA_SHIBS ;  Q0T2X5, MGLA_SHIF8 ;  P0AAG9, MGLA_SHIFL ;
DR   Q3Z057, MGLA_SHISS ;  Q2NUD6, MGLA_SODGM ;  Q73KK2, MGLA_TREDE ;
DR   Q56342, MGLA_TREPA ;  Q9KSD1, MGLA_VIBCH ;  Q8D4H4, MGLA_VIBVU ;
DR   Q7MG07, MGLA_VIBVY ;  Q1C9V1, MGLA_YERPA ;  Q7CHQ3, MGLA_YERPE ;
DR   Q1CGT1, MGLA_YERPN ;  Q66C83, MGLA_YERPS ;  Q8UA86, RBSA1_AGRT5;
DR   Q1BWN5, RBSA1_BURCA;  A0K718, RBSA1_BURCH;  Q0BFU0, RBSA1_BURCM;
DR   Q3JSI8, RBSA1_BURP1;  Q39GY8, RBSA1_BURS3;  Q2SVU4, RBSA1_BURTA;
DR   Q8XAW7, RBSA1_ECO57;  Q9CP98, RBSA1_PASMU;  Q2K9A3, RBSA1_RHIEC;
DR   Q1MHS1, RBSA1_RHIL3;  Q98K15, RBSA1_RHILO;  Q92S10, RBSA1_RHIME;
DR   Q1AXG5, RBSA1_RUBXD;  Q82CM5, RBSA1_STRAW;  Q8CK44, RBSA1_STRCO;
DR   Q9WXX0, RBSA1_THEMA;  Q8U949, RBSA2_AGRT5;  Q1BPL3, RBSA2_BURCA;
DR   A0B1M7, RBSA2_BURCH;  Q0B7X0, RBSA2_BURCM;  Q3JHZ1, RBSA2_BURP1;
DR   Q398W2, RBSA2_BURS3;  Q2T8T6, RBSA2_BURTA;  Q8X5Q4, RBSA2_ECO57;
DR   Q9CL63, RBSA2_PASMU;  Q2K204, RBSA2_RHIEC;  Q1M5X4, RBSA2_RHIL3;
DR   Q987E7, RBSA2_RHILO;  Q92W60, RBSA2_RHIME;  Q1AVD3, RBSA2_RUBXD;
DR   Q825P1, RBSA2_STRAW;  Q9RDI1, RBSA2_STRCO;  Q9X051, RBSA2_THEMA;
DR   Q2K0S7, RBSA3_RHIEC;  Q1M360, RBSA3_RHIL3;  Q92UI2, RBSA3_RHIME;
DR   Q1ARR5, RBSA3_RUBXD;  Q3MB44, RBSA_ANAVT ;  Q81V36, RBSA_BACAN ;
DR   Q73DH7, RBSA_BACC1 ;  Q81HW8, RBSA_BACCR ;  Q63FX9, RBSA_BACCZ ;
DR   Q9K6J9, RBSA_BACHD ;  Q6HNE7, RBSA_BACHK ;  Q65E55, RBSA_BACLD ;
DR   Q5WC31, RBSA_BACSK ;  P36947, RBSA_BACSU ;  Q62K91, RBSA_BURMA ;
DR   Q63P06, RBSA_BURPS ;  Q13LX0, RBSA_BURXL ;  Q7NTN6, RBSA_CHRVO ;
DR   Q0TPX5, RBSA_CLOP1 ;  Q8XJX3, RBSA_CLOPE ;  Q0SSJ0, RBSA_CLOPS ;
DR   Q891M1, RBSA_CLOTE ;  Q8NR12, RBSA_CORGL ;  Q1J3P2, RBSA_DEIGD ;
DR   Q0TAW0, RBSA_ECOL5 ;  Q8FBS3, RBSA_ECOL6 ;  P04983, RBSA_ECOLI ;
DR   Q1R4I3, RBSA_ECOUT ;  Q6DB87, RBSA_ERWCT ;  Q5KUX3, RBSA_GEOKA ;
DR   Q4QN44, RBSA_HAEI8 ;  P44735, RBSA_HAEIN ;  Q2SJ99, RBSA_HAHCH ;
DR   Q28P50, RBSA_JANSC ;  Q03CA4, RBSA_LACC3 ;  Q9CF44, RBSA_LACLA ;
DR   Q02XM9, RBSA_LACLS ;  Q11C01, RBSA_MESSB ;  Q8ENB3, RBSA_OCEIH ;
DR   Q7NA79, RBSA_PHOLL ;  Q6LH11, RBSA_PHOPR ;  Q88J90, RBSA_PSEPK ;
DR   Q7UU57, RBSA_RHOBA ;  Q3J3V9, RBSA_RHOS4 ;  Q0S9A4, RBSA_RHOSR ;
DR   Q164K3, RBSA_ROSDO ;  Q57HW1, RBSA_SALCH ;  Q5PJX5, RBSA_SALPA ;
DR   Q8Z2R4, RBSA_SALTI ;  Q8ZKV9, RBSA_SALTY ;  Q329G7, RBSA_SHIDS ;
DR   Q3YVK8, RBSA_SHISS ;  Q1GHE5, RBSA_SILST ;  Q3K3R2, RBSA_STRA1 ;
DR   Q8E7N9, RBSA_STRA3 ;  Q8E281, RBSA_STRA5 ;  Q8RD43, RBSA_THETN ;
DR   Q9KN37, RBSA_VIBCH ;  Q5E4V6, RBSA_VIBF1 ;  Q87H79, RBSA_VIBPA ;
DR   Q8D7T7, RBSA_VIBVU ;  Q7MEV1, RBSA_VIBVY ;  Q1C1B8, RBSA_YERPA ;
DR   Q7CG00, RBSA_YERPE ;  Q1CDJ0, RBSA_YERPN ;  Q664G2, RBSA_YERPS ;
DR   Q8UBN2, RGMG1_AGRT5;  Q1BX03, RGMG1_BURCA;  A0K6Q0, RGMG1_BURCH;
DR   Q0BGD7, RGMG1_BURCM;  Q399X3, RGMG1_BURS3;  Q2KAW9, RGMG1_RHIEC;
DR   Q92MP8, RGMG1_RHIME;  Q8UAK2, RGMG2_AGRT5;  Q1BQ82, RGMG2_BURCA;
DR   A0B297, RGMG2_BURCH;  Q0BG60, RGMG2_BURCM;  Q39HA1, RGMG2_BURS3;
DR   Q2K353, RGMG2_RHIEC;  Q92TS8, RGMG2_RHIME;  Q8U9B0, RGMG3_AGRT5;
DR   Q1BGC0, RGMG3_BURCA;  A0KE25, RGMG3_BURCH;  Q0B775, RGMG3_BURCM;
DR   Q9KAG5, RGMG_BACHD ;  Q13FD9, RGMG_BURXL ;  Q5KYQ7, RGMG_GEOKA ;
DR   Q2SMT0, RGMG_HAHCH ;  Q48GY7, RGMG_PSE14 ;  Q4KDI2, RGMG_PSEF5 ;
DR   Q87ZE0, RGMG_PSESM ;  Q4ZRC6, RGMG_PSEU2 ;  Q8Y003, RGMG_RALSO ;
DR   Q1MAA2, RGMG_RHIL3 ;  Q21TR5, RGMG_RHOFD ;  Q8RBQ1, RGMG_THETN ;
DR   Q2YJE7, XYLG_BRUA2 ;  Q576H3, XYLG_BRUAB ;  Q8YDN0, XYLG_BRUME ;
DR   Q8FUR8, XYLG_BRUSU ;  Q1BG93, XYLG_BURCA ;  A0KE53, XYLG_BURCH ;
DR   Q0B1U4, XYLG_BURCM ;  Q2SW38, XYLG_BURTA ;  Q13RB6, XYLG_BURXL ;
DR   Q8XDM1, XYLG_ECO57 ;  Q0TBN5, XYLG_ECOL5 ;  Q8FCE2, XYLG_ECOL6 ;
DR   P37388, XYLG_ECOLI ;  Q1R528, XYLG_ECOUT ;  Q6DB03, XYLG_ERWCT ;
DR   Q5KYS1, XYLG_GEOKA ;  P45046, XYLG_HAEIN ;  Q0I348, XYLG_HAES1 ;
DR   Q2RGX2, XYLG_MOOTA ;  Q6LUY1, XYLG_PHOPR ;  Q48J74, XYLG_PSE14 ;
DR   Q3KDW2, XYLG_PSEPF ;  Q880Z2, XYLG_PSESM ;  Q4ZSF3, XYLG_PSEU2 ;
DR   Q8XPK6, XYLG_RALSO ;  Q31V51, XYLG_SHIBS ;  Q0SY86, XYLG_SHIF8 ;
DR   Q83J33, XYLG_SHIFL ;  Q6VMN4, XYLG_THEP3 ;  Q1C0D5, XYLG_YERPA ;
DR   Q7CFR2, XYLG_YERPE ;  Q1CDC0, XYLG_YERPN ;  Q663Y5, XYLG_YERPS ;
//
ID   3.6.3.18
DE   Oligosaccharide-transporting ATPase.
CA   ATP + H(2)O + oligosaccharide(Out) = ADP + phosphate +
CA   oligosaccharide(In).
CC   -!- A bacterial enzyme that imports lactose, melibiose and raffinose.
PR   PROSITE; PDOC00185;
//
ID   3.6.3.19
DE   Maltose-transporting ATPase.
CA   ATP + H(2)O + maltose(Out) = ADP + phosphate + maltose(In).
CC   -!- Comprises bacterial enzymes that import maltose and maltose
CC       oligosaccharides.
PR   PROSITE; PDOC00185;
DR   P68188, MALK_ECO57 ;  Q0TA26, MALK_ECOL5 ;  Q8FB37, MALK_ECOL6 ;
DR   P68187, MALK_ECOLI ;  Q1R3Q1, MALK_ECOUT ;  P18813, MALK_ENTAE ;
DR   Q65QT6, MALK_MANSM ;  Q7N986, MALK_PHOLL ;  P41124, MALK_PHOLU ;
DR   Q6LK87, MALK_PHOPR ;  Q57GZ7, MALK_SALCH ;  Q5PKZ8, MALK_SALPA ;
DR   Q8Z1U0, MALK_SALTI ;  P19566, MALK_SALTY ;  Q0SXQ1, MALK_SHIF8 ;
DR   Q7UBD0, MALK_SHIFL ;  Q3YUV0, MALK_SHISS ;  Q9KL04, MALK_VIBCH ;
DR   Q5DZC6, MALK_VIBF1 ;  Q87GB5, MALK_VIBPA ;  Q8D3V0, MALK_VIBVU ;
DR   Q7MFC4, MALK_VIBVY ;  Q1CC21, MALK_YERPA ;  Q8ZAS8, MALK_YERPE ;
DR   Q1CNR8, MALK_YERPN ;  Q664X5, MALK_YERPS ;
//
ID   3.6.3.20
DE   Glycerol-3-phosphate-transporting ATPase.
CA   ATP + H(2)O + glycerol-3-phosphate(Out) = ADP + phosphate + glycerol-3-
CA   phosphate(In).
CC   -!- A bacterial enzyme that imports phosphorylated glycerol.
PR   PROSITE; PDOC00185;
DR   Q8UII7, UGPC1_AGRT5;  Q2K6L3, UGPC1_RHIEC;  Q1MCN6, UGPC1_RHIL3;
DR   Q8UBB7, UGPC2_AGRT5;  Q2K4V4, UGPC2_RHIEC;  Q1M8R6, UGPC2_RHIL3;
DR   Q8UB29, UGPC3_AGRT5;  Q2K1C8, UGPC3_RHIEC;  Q1M589, UGPC3_RHIL3;
DR   A1URR2, UGPC_BARBK ;  Q6G5J0, UGPC_BARHE ;  Q6G194, UGPC_BARQU ;
DR   Q2L0H5, UGPC_BORA1 ;  Q7WID6, UGPC_BORBR ;  Q7W6G5, UGPC_BORPA ;
DR   Q7VYN2, UGPC_BORPE ;  Q89WG0, UGPC_BRAJA ;  Q2YKR8, UGPC_BRUA2 ;
DR   Q578E9, UGPC_BRUAB ;  Q8YCB1, UGPC_BRUME ;  Q8FW07, UGPC_BRUSU ;
DR   Q1BRZ8, UGPC_BURCA ;  A0K3S5, UGPC_BURCH ;  Q0BIZ6, UGPC_BURCM ;
DR   Q62GB4, UGPC_BURMA ;  Q3JMW7, UGPC_BURP1 ;  Q63Q62, UGPC_BURPS ;
DR   Q39KB9, UGPC_BURS3 ;  Q2SU77, UGPC_BURTA ;  Q13TV1, UGPC_BURXL ;
DR   Q1QTX6, UGPC_CHRSD ;  Q7NRX5, UGPC_CHRVO ;  Q0K998, UGPC_CUPNH ;
DR   Q46ZM0, UGPC_CUPPJ ;  Q8X6U5, UGPC_ECO57 ;  A1AGY1, UGPC_ECOK1 ;
DR   Q0TC10, UGPC_ECOL5 ;  Q8FCQ2, UGPC_ECOL6 ;  P10907, UGPC_ECOLI ;
DR   Q1R5H8, UGPC_ECOUT ;  Q6CZ34, UGPC_ERWCT ;  Q28QL7, UGPC_JANSC ;
DR   A1B9Q7, UGPC_PARDP ;  A1SWH9, UGPC_PSYIN ;  Q1LLP5, UGPC_RALME ;
DR   Q8XZX8, UGPC_RALSO ;  Q98G42, UGPC_RHILO ;  Q92WD6, UGPC_RHIME ;
DR   Q2J2E9, UGPC_RHOP2 ;  Q07UI9, UGPC_RHOP5 ;  Q6NDQ0, UGPC_RHOPA ;
DR   Q21CA3, UGPC_RHOPB ;  Q13ER6, UGPC_RHOPS ;  A3PRY1, UGPC_RHOS1 ;
DR   Q3IX40, UGPC_RHOS4 ;  Q164Y5, UGPC_ROSDO ;  Q57IS3, UGPC_SALCH ;
DR   Q5PJL1, UGPC_SALPA ;  Q8Z245, UGPC_SALTI ;  Q8ZLF4, UGPC_SALTY ;
DR   Q31VH5, UGPC_SHIBS ;  Q3YW77, UGPC_SHISS ;  Q5LX21, UGPC_SILPO ;
DR   Q1GID1, UGPC_SILST ;  Q9KRT4, UGPC_VIBCH ;  Q8D954, UGPC_VIBVU ;
DR   Q7MLB8, UGPC_VIBVY ;  A1JIE0, UGPC_YERE8 ;  Q1CBH2, UGPC_YERPA ;
DR   Q74R28, UGPC_YERPE ;  Q1CNC6, UGPC_YERPN ;  Q66FU4, UGPC_YERPS ;
//
ID   3.6.3.21
DE   Polar-amino-acid-transporting ATPase.
AN   Histidine permease.
CA   ATP + H(2)O + polar amino acid(Out) = ADP + phosphate + polar amino
CA   acid(In).
CC   -!- Comprises bacterial enzymes that import His, Arg, Lys, Glu, Gln, Asp,
CC       ornithine, octopine and nopaline.
PR   PROSITE; PDOC00185;
//
ID   3.6.3.22
DE   Nonpolar-amino-acid-transporting ATPase.
CA   ATP + H(2)O + nonpolar amino acid(Out) = ADP + phosphate + nonpolar amino
CA   acid(In).
CC   -!- Comprises bacterial enzymes that import Leu, Ile and Val.
PR   PROSITE; PDOC00185;
//
ID   3.6.3.23
DE   Oligopeptide-transporting ATPase.
AN   Oligopeptide permease.
CA   ATP + H(2)O + oligopeptide(Out) = ADP + phosphate + oligopeptide(In).
CC   -!- A bacterial enzyme that imports di- and oligopeptides.
PR   PROSITE; PDOC00185;
//
ID   3.6.3.24
DE   Nickel-transporting ATPase.
CA   ATP + H(2)O + Ni(2+)(Out) = ADP + phosphate + Ni(2+)(In).
CC   -!- A bacterial enzyme that imports Ni(2+).
PR   PROSITE; PDOC00185;
DR   Q2YL70, NIKD_BRUA2 ;  Q578S8, NIKD_BRUAB ;  Q8YCN8, NIKD_BRUME ;
DR   Q8FVM9, NIKD_BRUSU ;  Q8X5U1, NIKD_ECO57 ;  Q0TBX9, NIKD_ECOL5 ;
DR   Q8FCN0, NIKD_ECOL6 ;  P33593, NIKD_ECOLI ;  Q1R5D9, NIKD_ECOUT ;
DR   Q88HL1, NIKD_PSEPK ;  Q2RS21, NIKD_RHORT ;  Q31VE7, NIKD_SHIBS ;
DR   Q32AQ2, NIKD_SHIDS ;  Q0SZJ4, NIKD_SHIF8 ;  Q83J78, NIKD_SHIFL ;
DR   Q3YW49, NIKD_SHISS ;  Q2YL69, NIKE_BRUA2 ;  Q578S7, NIKE_BRUAB ;
DR   Q8YCN7, NIKE_BRUME ;  Q8FVN0, NIKE_BRUSU ;  Q8X4L6, NIKE_ECO57 ;
DR   Q0TBX8, NIKE_ECOL5 ;  Q8FCM9, NIKE_ECOL6 ;  P33594, NIKE_ECOLI ;
DR   Q1R5D8, NIKE_ECOUT ;  Q88HL0, NIKE_PSEPK ;  Q2RS22, NIKE_RHORT ;
DR   Q31VE6, NIKE_SHIBS ;  Q32AQ1, NIKE_SHIDS ;  Q0SZJ3, NIKE_SHIF8 ;
DR   Q83J77, NIKE_SHIFL ;  Q3YW48, NIKE_SHISS ;
//
ID   3.6.3.25
DE   Sulfate-transporting ATPase.
CA   ATP + H(2)O + sulfate(Out) = ADP + phosphate + sulfate(In).
CC   -!- A bacterial enzyme that imports sulfate and thiosulfate anions.
PR   PROSITE; PDOC00185;
DR   Q8UH62, CYSA1_AGRT5;  Q7NX01, CYSA1_CHRVO;  Q92XW1, CYSA1_RHIME;
DR   Q8EBC3, CYSA1_SHEON;  Q8UA73, CYSA2_AGRT5;  Q7NWX3, CYSA2_CHRVO;
DR   Q92VJ2, CYSA2_RHIME;  Q8E8K8, CYSA2_SHEON;  Q6F9A8, CYSA_ACIAD ;
DR   Q85A69, CYSA_ANTFO ;  O31339, CYSA_BACC1 ;  Q81GU1, CYSA_BACCR ;
DR   Q9K876, CYSA_BACHD ;  Q7WGW1, CYSA_BORBR ;  Q7W9U5, CYSA_BORPA ;
DR   Q7VZE5, CYSA_BORPE ;  Q89UD2, CYSA_BRAJA ;  P63353, CYSA_BRUME ;
DR   P63354, CYSA_BRUSU ;  Q93DX8, CYSA_BURCE ;  Q62K82, CYSA_BURMA ;
DR   Q63TY1, CYSA_BURPS ;  Q9A7X1, CYSA_CAUCR ;  P56344, CYSA_CHLVU ;
DR   Q9G4F5, CYSA_CUCSA ;  Q8XBJ8, CYSA_ECO57 ;  Q8FFB3, CYSA_ECOL6 ;
DR   P16676, CYSA_ECOLI ;  Q6D201, CYSA_ERWCT ;  Q7NIW1, CYSA_GLOVI ;
DR   Q72PE5, CYSA_LEPIC ;  Q8F6Z1, CYSA_LEPIN ;  Q65T42, CYSA_MANSM ;
DR   P10091, CYSA_MARPO ;  Q9MUN1, CYSA_MESVI ;  Q609Q1, CYSA_METCA ;
DR   P0A4W3, CYSA_MYCBO ;  Q73XU8, CYSA_MYCPA ;  P0A4W2, CYSA_MYCTU ;
DR   Q9JUX4, CYSA_NEIMA ;  Q9JZW0, CYSA_NEIMB ;  Q9TKX3, CYSA_NEPOL ;
DR   Q82WT5, CYSA_NITEU ;  Q5YZY9, CYSA_NOCFA ;  Q8Z0H0, CYSA_NOSS1 ;
DR   Q7N6Z2, CYSA_PHOLL ;  Q9I6L0, CYSA_PSEAE ;  Q88CL2, CYSA_PSEPK ;
DR   Q88AS5, CYSA_PSESM ;  Q8XZP8, CYSA_RALSO ;  Q98K23, CYSA_RHILO ;
DR   Q6NBT1, CYSA_RHOPA ;  Q8Z4V6, CYSA_SALTI ;  P40860, CYSA_SALTY ;
DR   Q7UC29, CYSA_SHIFL ;  P14788, CYSA_SYNE7 ;  P74548, CYSA_SYNY3 ;
DR   Q8DIA0, CYSA_THEEB ;  Q9KUI0, CYSA_VIBCH ;  Q8D653, CYSA_VIBVU ;
DR   Q8PNN4, CYSA_XANAC ;  Q8PC11, CYSA_XANCP ;  Q9PDN2, CYSA_XYLFA ;
DR   Q87DT9, CYSA_XYLFT ;  Q8D0W8, CYSA_YERPE ;  Q668K6, CYSA_YERPS ;
DR   O31427, SKFE_BACSU ;
//
ID   3.6.3.26
DE   Nitrate-transporting ATPase.
CA   ATP + H(2)O + nitrate(Out) = ADP + phosphate + nitrate(In).
CC   -!- A bacterial enzyme that imports NO(3)(-), NO(2)(-) and OCN(-).
PR   PROSITE; PDOC00185;
//
ID   3.6.3.27
DE   Phosphate-transporting ATPase.
AN   ABC phosphate transporter.
CA   ATP + H(2)O + phosphate(Out) = ADP + phosphate + phosphate(In).
CC   -!- A bacterial enzyme that imports phosphate anions.
PR   PROSITE; PDOC00185;
DR   A0QQ70, PHNC_MYCS2 ;  Q3MH62, PSTB1_ANAVT;  Q65HC0, PSTB1_BACLD;
DR   Q5WET8, PSTB1_BACSK;  P46342, PSTB1_BACSU;  Q1QXH6, PSTB1_CHRSD;
DR   Q834B4, PSTB1_ENTFA;  Q6D2D5, PSTB1_ERWCT;  Q7NPP4, PSTB1_GLOVI;
DR   Q5V225, PSTB1_HALMA;  Q9HS13, PSTB1_HALSA;  Q5FM18, PSTB1_LACAC;
DR   Q74KF9, PSTB1_LACJO;  Q9CEW8, PSTB1_LACLA;  Q88YK8, PSTB1_LACPL;
DR   Q1WUX2, PSTB1_LACS1;  Q38YC2, PSTB1_LACSS;  P63364, PSTB1_LISIN;
DR   Q71WT3, PSTB1_LISMF;  P63363, PSTB1_LISMO;  Q2W8B4, PSTB1_MAGSA;
DR   Q7U172, PSTB1_MYCBO;  O53832, PSTB1_MYCTU;  Q3IS07, PSTB1_NATPD;
DR   Q3JDJ6, PSTB1_NITOC;  Q8YYE3, PSTB1_NOSS1;  Q6LU82, PSTB1_PHOPR;
DR   Q48HD9, PSTB1_PSE14;  Q88JJ0, PSTB1_PSEPK;  Q880A6, PSTB1_PSESM;
DR   Q4ZRT7, PSTB1_PSEU2;  Q1MLW4, PSTB1_RHIL3;  Q8EG82, PSTB1_SHEON;
DR   Q3K199, PSTB1_STRA1;  P63367, PSTB1_STRA3;  P63368, PSTB1_STRA5;
DR   Q8DU24, PSTB1_STRMU;  P63375, PSTB1_STRP1;  P0CZ36, PSTB1_STRP3;
DR   Q5XBY7, PSTB1_STRP6;  P63377, PSTB1_STRP8;  Q1JBJ5, PSTB1_STRPB;
DR   Q1JLH7, PSTB1_STRPC;  Q1JGL3, PSTB1_STRPD;  Q1J6D2, PSTB1_STRPF;
DR   Q48TC3, PSTB1_STRPM;  P63373, PSTB1_STRPN;  P0CZ37, PSTB1_STRPQ;
DR   P63374, PSTB1_STRR6;  Q5LZU3, PSTB1_STRT1;  Q5M4F3, PSTB1_STRT2;
DR   Q67RG2, PSTB1_SYMTH;  Q2JUA1, PSTB1_SYNJA;  Q2JMJ0, PSTB1_SYNJB;
DR   Q55196, PSTB1_SYNY3;  Q8RCU0, PSTB1_THETN;  Q9KU04, PSTB1_VIBCH;
DR   Q5E4D8, PSTB1_VIBF1;  Q87S48, PSTB1_VIBPA;  Q8DEW5, PSTB1_VIBVU;
DR   Q7MNI7, PSTB1_VIBVY;  Q1C5N7, PSTB1_YERPA;  Q8ZCX5, PSTB1_YERPE;
DR   Q1CK45, PSTB1_YERPN;  Q668E1, PSTB1_YERPS;  Q3MBW2, PSTB2_ANAVT;
DR   Q65HB9, PSTB2_BACLD;  Q5WET7, PSTB2_BACSK;  P46341, PSTB2_BACSU;
DR   Q1QSE9, PSTB2_CHRSD;  Q834B3, PSTB2_ENTFA;  Q6CYN3, PSTB2_ERWCT;
DR   Q7NNG3, PSTB2_GLOVI;  Q5V0G3, PSTB2_HALMA;  Q9HML8, PSTB2_HALSA;
DR   Q5FM17, PSTB2_LACAC;  Q74KF8, PSTB2_LACJO;  Q9CEW7, PSTB2_LACLA;
DR   Q88YK7, PSTB2_LACPL;  Q1WUX1, PSTB2_LACS1;  Q38YC1, PSTB2_LACSS;
DR   Q927Z7, PSTB2_LISIN;  Q71WT2, PSTB2_LISMF;  Q8Y4E9, PSTB2_LISMO;
DR   Q2W7J9, PSTB2_MAGSA;  Q7U0Z9, PSTB2_MYCBO;  P95302, PSTB2_MYCTU;
DR   Q3IQI3, PSTB2_NATPD;  Q3J8J2, PSTB2_NITOC;  Q8YYE2, PSTB2_NOSS1;
DR   Q6LSC4, PSTB2_PHOPR;  Q48BP8, PSTB2_PSE14;  Q88C57, PSTB2_PSEPK;
DR   Q87U31, PSTB2_PSESM;  Q4ZLA7, PSTB2_PSEU2;  Q1MIN0, PSTB2_RHIL3;
DR   Q8E9I8, PSTB2_SHEON;  Q3K198, PSTB2_STRA1;  P63369, PSTB2_STRA3;
DR   P63370, PSTB2_STRA5;  Q8DU23, PSTB2_STRMU;  P63378, PSTB2_STRP1;
DR   P0CZ38, PSTB2_STRP3;  Q5XBY6, PSTB2_STRP6;  Q8P0V3, PSTB2_STRP8;
DR   Q1JBJ4, PSTB2_STRPB;  Q1JLH6, PSTB2_STRPC;  Q1JGL2, PSTB2_STRPD;
DR   Q1J6D1, PSTB2_STRPF;  Q48TC2, PSTB2_STRPM;  Q97Q34, PSTB2_STRPN;
DR   P0CZ39, PSTB2_STRPQ;  Q8DPB4, PSTB2_STRR6;  Q5LZU2, PSTB2_STRT1;
DR   Q5M4F2, PSTB2_STRT2;  Q67RE7, PSTB2_SYMTH;  Q2JTU3, PSTB2_SYNJA;
DR   Q2JKC2, PSTB2_SYNJB;  Q55195, PSTB2_SYNY3;  Q8R9I2, PSTB2_THETN;
DR   Q9KN92, PSTB2_VIBCH;  Q5E3B8, PSTB2_VIBF1;  Q87G59, PSTB2_VIBPA;
DR   Q8D3X4, PSTB2_VIBVU;  Q7MFE8, PSTB2_VIBVY;  Q1C0A2, PSTB2_YERPA;
DR   Q8Z9T1, PSTB2_YERPE;  Q1CCI2, PSTB2_YERPN;  Q663R5, PSTB2_YERPS;
DR   Q3MA91, PSTB3_ANAVT;  Q2VYP7, PSTB3_MAGSA;  Q3IM36, PSTB3_NATPD;
DR   Q8YNJ3, PSTB3_NOSS1;  Q3JYY5, PSTB3_STRA1;  P63371, PSTB3_STRA3;
DR   P63372, PSTB3_STRA5;  P0A2V8, PSTB3_STRPN;  P0A2V9, PSTB3_STRR6;
DR   P73788, PSTB3_SYNY3;  Q3M4H6, PSTB4_ANAVT;  Q3M4H5, PSTB5_ANAVT;
DR   Q6FCW7, PSTB_ACIAD ;  Q1IMC7, PSTB_ACIBL ;  Q9YG51, PSTB_AERPE ;
DR   Q8UI76, PSTB_AGRT5 ;  Q0VL18, PSTB_ALCBS ;  Q6WB51, PSTB_ALCFA ;
DR   Q0A9K1, PSTB_ALHEH ;  Q2IGQ6, PSTB_ANADE ;  O67154, PSTB_AQUAE ;
DR   O28912, PSTB_ARCFU ;  Q5P1F3, PSTB_AROAE ;  Q81LW6, PSTB_BACAN ;
DR   Q730R7, PSTB_BACC1 ;  Q818I7, PSTB_BACCR ;  Q634R8, PSTB_BACCZ ;
DR   Q5LBQ4, PSTB_BACFN ;  Q64SM5, PSTB_BACFR ;  Q9K8L5, PSTB_BACHD ;
DR   Q6HDP8, PSTB_BACHK ;  Q8A853, PSTB_BACTN ;  Q6G4T6, PSTB_BARHE ;
DR   Q6G0L7, PSTB_BARQU ;  Q6MMH0, PSTB_BDEBA ;  Q8G7F4, PSTB_BIFLO ;
DR   Q2KVN7, PSTB_BORA1 ;  Q0SNU4, PSTB_BORAP ;  Q7WMC3, PSTB_BORBR ;
DR   O51236, PSTB_BORBU ;  Q662E6, PSTB_BORGA ;  Q7W8Q6, PSTB_BORPA ;
DR   Q7VZ66, PSTB_BORPE ;  Q89VF2, PSTB_BRAJA ;  Q2YQT8, PSTB_BRUA2 ;
DR   Q57AC2, PSTB_BRUAB ;  P63361, PSTB_BRUME ;  P63362, PSTB_BRUSU ;
DR   Q1BXC3, PSTB_BURCA ;  Q62L74, PSTB_BURMA ;  Q3JTS8, PSTB_BURP1 ;
DR   Q63V79, PSTB_BURPS ;  Q39HM4, PSTB_BURS3 ;  Q9XBG1, PSTB_BURSP ;
DR   Q2SUW7, PSTB_BURTA ;  Q13W55, PSTB_BURXL ;  Q9PHQ1, PSTB_CAMJE ;
DR   Q5HVF4, PSTB_CAMJR ;  Q3AAA4, PSTB_CARHZ ;  B8GYG4, PSTB_CAUCN ;
DR   P0CAT6, PSTB_CAUCR ;  Q3ATA4, PSTB_CHLCH ;  Q8KDZ5, PSTB_CHLTE ;
DR   Q7NZI7, PSTB_CHRVO ;  Q97IE0, PSTB_CLOAB ;  Q180A5, PSTB_CLOD6 ;
DR   Q0TTG6, PSTB_CLOP1 ;  Q8XMP8, PSTB_CLOPE ;  Q0SVB6, PSTB_CLOPS ;
DR   Q895Y0, PSTB_CLOTE ;  Q47Y12, PSTB_COLP3 ;  Q8FMN9, PSTB_COREF ;
DR   Q8NMK1, PSTB_CORGL ;  Q4JXC5, PSTB_CORJK ;  Q46ZA5, PSTB_CUPPJ ;
DR   Q11NG0, PSTB_CYTH3 ;  Q47A37, PSTB_DECAR ;  Q3ZA58, PSTB_DEHE1 ;
DR   Q3ZWN4, PSTB_DEHSC ;  Q1J0N0, PSTB_DEIGD ;  Q9RYZ3, PSTB_DEIRA ;
DR   Q30YR3, PSTB_DESDG ;  Q24PY8, PSTB_DESHY ;  Q6AM16, PSTB_DESPS ;
DR   Q72D46, PSTB_DESVH ;  P0AAH2, PSTB_ECO57 ;  Q0TAY4, PSTB_ECOL5 ;
DR   P0AAH1, PSTB_ECOL6 ;  P0AAH0, PSTB_ECOLI ;  Q1R4L0, PSTB_ECOUT ;
DR   Q9AML4, PSTB_EDWTA ;  Q5FFT1, PSTB_EHRRG ;  Q5HAV5, PSTB_EHRRW ;
DR   O32487, PSTB_ENTCL ;  Q2J534, PSTB_FRASC ;  Q5KX47, PSTB_GEOKA ;
DR   Q39S52, PSTB_GEOMG ;  Q74E68, PSTB_GEOSL ;  Q5FT15, PSTB_GLUOX ;
DR   Q0BTP1, PSTB_GRABC ;  Q4QK92, PSTB_HAEI8 ;  Q2SNX4, PSTB_HAHCH ;
DR   Q18K56, PSTB_HALWD ;  Q8GDV4, PSTB_HELMO ;  Q0C0L5, PSTB_HYPNA ;
DR   Q5QVB0, PSTB_IDILO ;  Q28Q03, PSTB_JANSC ;  Q1GAD3, PSTB_LACDA ;
DR   Q6ADG4, PSTB_LEIXX ;  Q0ASG3, PSTB_MARMM ;  Q6F1N1, PSTB_MESFL ;
DR   Q11DN5, PSTB_MESSB ;  Q8TSA8, PSTB_METAC ;  Q46BM0, PSTB_METBF ;
DR   Q12XW6, PSTB_METBU ;  Q609Z8, PSTB_METCA ;  Q1H377, PSTB_METFK ;
DR   Q2FTF8, PSTB_METHJ ;  Q58418, PSTB_METJA ;  Q8TUR7, PSTB_METKA ;
DR   Q8PVF6, PSTB_METMA ;  Q6LY93, PSTB_METMP ;  Q2NHW1, PSTB_METST ;
DR   O27764, PSTB_METTH ;  Q2RM86, PSTB_MOOTA ;  Q2SS06, PSTB_MYCCT ;
DR   Q7NC40, PSTB_MYCGA ;  P47650, PSTB_MYCGE ;  Q49588, PSTB_MYCIT ;
DR   Q50046, PSTB_MYCLE ;  Q6KIS8, PSTB_MYCMO ;  Q6MTC1, PSTB_MYCMS ;
DR   Q743D1, PSTB_MYCPA ;  Q8EUJ1, PSTB_MYCPE ;  P75186, PSTB_MYCPN ;
DR   A0R4C0, PSTB_MYCS2 ;  P0C560, PSTB_MYCSM ;  Q1B3B4, PSTB_MYCSS ;
DR   Q1D320, PSTB_MYXXD ;  Q82VR4, PSTB_NITEU ;  Q1QQH1, PSTB_NITHX ;
DR   Q2YA30, PSTB_NITMU ;  Q3SVB5, PSTB_NITWN ;  Q5Z293, PSTB_NOCFA ;
DR   Q2G607, PSTB_NOVAD ;  Q8ELT4, PSTB_OCEIH ;  Q9CNJ7, PSTB_PASMU ;
DR   Q3A6U0, PSTB_PELCD ;  Q3B3H7, PSTB_PELLD ;  Q4FLF6, PSTB_PELUB ;
DR   Q7N9U4, PSTB_PHOLL ;  Q12BB2, PSTB_POLSJ ;  Q6AAX3, PSTB_PROAC ;
DR   Q31BF6, PSTB_PROM9 ;  Q7VCZ3, PSTB_PROMA ;  Q7V7P0, PSTB_PROMM ;
DR   Q7V1X3, PSTB_PROMP ;  Q46L27, PSTB_PROMT ;  Q15QL7, PSTB_PSEA6 ;
DR   Q51546, PSTB_PSEAE ;  Q4K3K9, PSTB_PSEF5 ;  Q3ILC5, PSTB_PSEHT ;
DR   Q3K4F5, PSTB_PSEPF ;  Q9Z411, PSTB_PSEPU ;  Q4FQD1, PSTB_PSYA2 ;
DR   Q1Q8K4, PSTB_PSYCK ;  Q9UZU7, PSTB_PYRAB ;  Q8ZX91, PSTB_PYRAE ;
DR   Q8U242, PSTB_PYRFU ;  Q5JEP9, PSTB_PYRKO ;  Q1LLB5, PSTB_RALME ;
DR   Q8XZ72, PSTB_RALSO ;  Q2KCV5, PSTB_RHIEC ;  Q98FL5, PSTB_RHILO ;
DR   Q92SA1, PSTB_RHIME ;  Q7UP21, PSTB_RHOBA ;  Q221H2, PSTB_RHOFD ;
DR   Q2J220, PSTB_RHOP2 ;  Q6N0I5, PSTB_RHOPA ;  Q20WP4, PSTB_RHOPB ;
DR   Q13CR0, PSTB_RHOPS ;  Q2RWU0, PSTB_RHORT ;  Q3J376, PSTB_RHOS4 ;
DR   Q0S736, PSTB_RHOSR ;  Q166A0, PSTB_ROSDO ;  Q1AXT9, PSTB_RUBXD ;
DR   Q21E72, PSTB_SACD2 ;  Q57HY8, PSTB_SALCH ;  Q5PKW4, PSTB_SALPA ;
DR   Q2S081, PSTB_SALRD ;  P63366, PSTB_SALTI ;  P63365, PSTB_SALTY ;
DR   Q12L15, PSTB_SHEDO ;  Q084V3, PSTB_SHEFN ;  Q0HH38, PSTB_SHESM ;
DR   Q0HTE5, PSTB_SHESR ;  Q31UX2, PSTB_SHIBS ;  Q329R2, PSTB_SHIDS ;
DR   P0AAH3, PSTB_SHIFL ;  Q3YVL7, PSTB_SHISS ;  Q5LS19, PSTB_SILPO ;
DR   Q1GH74, PSTB_SILST ;  Q1GUY1, PSTB_SPHAL ;  Q6XYT0, PSTB_SPIKU ;
DR   Q2FH51, PSTB_STAA3 ;  Q2FYQ0, PSTB_STAA8 ;  Q2YXY2, PSTB_STAAB ;
DR   P69881, PSTB_STAAC ;  P69878, PSTB_STAAM ;  P69879, PSTB_STAAN ;
DR   Q6GH21, PSTB_STAAR ;  Q6G9H4, PSTB_STAAS ;  P69880, PSTB_STAAW ;
DR   Q5HPF5, PSTB_STAEQ ;  Q8CPA1, PSTB_STAES ;  Q4L691, PSTB_STAHJ ;
DR   Q49XI8, PSTB_STAS1 ;  Q82G23, PSTB_STRAW ;  Q9KZW2, PSTB_STRCO ;
DR   Q9EUS2, PSTB_STRGR ;  Q30PC0, PSTB_SULDN ;  Q97ZT9, PSTB_SULSO ;
DR   Q2LTG0, PSTB_SYNAS ;  Q31KE8, PSTB_SYNE7 ;  Q5N1G5, PSTB_SYNP6 ;
DR   Q7U6R4, PSTB_SYNPX ;  Q0IAC3, PSTB_SYNS3 ;  Q3AXX4, PSTB_SYNS9 ;
DR   Q3AJS9, PSTB_SYNSC ;  Q8DGZ3, PSTB_THEEB ;  Q47L96, PSTB_THEFY ;
DR   Q9X0Y8, PSTB_THEMA ;  Q72GX5, PSTB_THET2 ;  Q5SLN1, PSTB_THET8 ;
DR   Q31I88, PSTB_THICR ;  Q3SJQ8, PSTB_THIDA ;  Q10YP7, PSTB_TRIEI ;
DR   Q83HT1, PSTB_TROW8 ;  Q83GE8, PSTB_TROWT ;  Q9PQU3, PSTB_UREPA ;
DR   Q7M9G3, PSTB_WOLSU ;  Q8PM59, PSTB_XANAC ;  Q3BV68, PSTB_XANC5 ;
DR   Q4UT63, PSTB_XANC8 ;  Q8PAG0, PSTB_XANCP ;  Q2P2Y5, PSTB_XANOM ;
DR   Q5H002, PSTB_XANOR ;  Q9PBK0, PSTB_XYLFA ;  Q87C88, PSTB_XYLFT ;
DR   Q5NNN6, PSTB_ZYMMO ;
//
ID   3.6.3.28
DE   Phosphonate-transporting ATPase.
CA   ATP + H(2)O + phosphonate(Out) = ADP + phosphate + phosphonate(In).
CC   -!- A bacterial enzyme that imports phosphonate and organophosphate
CC       anions.
PR   PROSITE; PDOC00185;
DR   Q9KFN9, PHNC1_BACHD;  Q0K4I1, PHNC1_CUPNH;  Q5V6B8, PHNC1_HALMA;
DR   Q18KE1, PHNC1_HALWD;  Q3ISC1, PHNC1_NATPD;  Q8YUV1, PHNC1_NOSS1;
DR   Q8ESM5, PHNC1_OCEIH;  Q48NM1, PHNC1_PSE14;  Q02QM1, PHNC1_PSEAB;
DR   Q9HYT0, PHNC1_PSEAE;  Q889G0, PHNC1_PSESM;  Q4ZYK8, PHNC1_PSEU2;
DR   Q1LQB5, PHNC1_RALME;  Q222W0, PHNC1_RHOFD;  Q2IYS5, PHNC1_RHOP2;
DR   Q07PZ0, PHNC1_RHOP5;  Q6NBX6, PHNC1_RHOPA;  Q20ZP0, PHNC1_RHOPB;
DR   Q16BC5, PHNC1_ROSDO;  Q1GMA8, PHNC1_SILST;  Q2JPW6, PHNC1_SYNJB;
DR   Q119J0, PHNC1_TRIEI;  Q9KFL0, PHNC2_BACHD;  Q0K1N8, PHNC2_CUPNH;
DR   Q5UW69, PHNC2_HALMA;  Q18H36, PHNC2_HALWD;  Q3IM24, PHNC2_NATPD;
DR   Q8YUI9, PHNC2_NOSS1;  Q8CUY0, PHNC2_OCEIH;  Q48HL2, PHNC2_PSE14;
DR   Q02QE8, PHNC2_PSEAB;  Q9HYL7, PHNC2_PSEAE;  Q882S0, PHNC2_PSESM;
DR   Q4ZU82, PHNC2_PSEU2;  Q1LJ08, PHNC2_RALME;  Q21Y06, PHNC2_RHOFD;
DR   Q2ISN3, PHNC2_RHOP2;  Q07LY2, PHNC2_RHOP5;  Q6NA00, PHNC2_RHOPA;
DR   Q20Y31, PHNC2_RHOPB;  Q166X0, PHNC2_ROSDO;  Q1GKZ0, PHNC2_SILST;
DR   Q2JLH7, PHNC2_SYNJB;  Q10V16, PHNC2_TRIEI;  Q9K8N1, PHNC3_BACHD;
DR   Q8YK28, PHNC3_NOSS1;  Q8UIW7, PHNC_AGRT5 ;  Q6WB63, PHNC_ALCFA ;
DR   Q2IN45, PHNC_ANADE ;  Q3MGT2, PHNC_ANAVT ;  Q81Y10, PHNC_BACAN ;
DR   Q733D6, PHNC_BACC1 ;  Q81A96, PHNC_BACCR ;  Q637E2, PHNC_BACCZ ;
DR   Q6HFB5, PHNC_BACHK ;  Q5WIL7, PHNC_BACSK ;  Q6MIP7, PHNC_BDEBA ;
DR   Q7WNT8, PHNC_BORBR ;  Q7W148, PHNC_BORPA ;  Q89C51, PHNC_BRAJA ;
DR   Q62H59, PHNC_BURMA ;  Q3JNY2, PHNC_BURP1 ;  Q63R24, PHNC_BURPS ;
DR   Q13LC4, PHNC_BURXL ;  Q9AB70, PHNC_CAUCR ;  Q1R0Z6, PHNC_CHRSD ;
DR   Q8NQH4, PHNC_CORGL ;  Q46TK4, PHNC_CUPPJ ;  Q47F10, PHNC_DECAR ;
DR   Q30W28, PHNC_DESDG ;  Q72AQ6, PHNC_DESVH ;  Q8XDV7, PHNC_ECO57 ;
DR   Q0T9T7, PHNC_ECOL5 ;  Q8FAV1, PHNC_ECOL6 ;  P16677, PHNC_ECOLI ;
DR   Q1R3F6, PHNC_ECOUT ;  Q2JB14, PHNC_FRASC ;  Q8REG7, PHNC_FUSNN ;
DR   Q9HNI8, PHNC_HALSA ;  Q0BZD8, PHNC_HYPNA ;  Q5FMM1, PHNC_LACAC ;
DR   Q035E0, PHNC_LACC3 ;  Q1GC08, PHNC_LACDA ;  Q04CG8, PHNC_LACDB ;
DR   Q046T0, PHNC_LACGA ;  Q74LQ3, PHNC_LACJO ;  Q9CIQ6, PHNC_LACLA ;
DR   Q032D0, PHNC_LACLS ;  Q88YN5, PHNC_LACPL ;  Q0ASQ1, PHNC_MARMM ;
DR   Q6F0P3, PHNC_MESFL ;  Q2SR40, PHNC_MYCCT ;  Q6MUF4, PHNC_MYCMS ;
DR   Q5YTW4, PHNC_NOCFA ;  Q12BC9, PHNC_POLSJ ;  Q1IEK7, PHNC_PSEE4 ;
DR   Q3KDI1, PHNC_PSEPF ;  Q88PM5, PHNC_PSEPK ;  Q6RCE0, PHNC_PSEST ;
DR   Q2KDV1, PHNC_RHIEC ;  Q1MMZ3, PHNC_RHIL3 ;  Q98GF5, PHNC_RHILO ;
DR   Q92V71, PHNC_RHIME ;  Q132E8, PHNC_RHOPS ;  Q31TP8, PHNC_SHIBS ;
DR   Q329I3, PHNC_SHIDS ;  Q0SXV5, PHNC_SHIF8 ;  Q83P97, PHNC_SHIFL ;
DR   Q3YUN6, PHNC_SHISS ;  Q5LVC2, PHNC_SILPO ;  Q2FKB7, PHNC_STAA3 ;
DR   Q2G1L8, PHNC_STAA8 ;  Q2YUY7, PHNC_STAAB ;  Q5HJM6, PHNC_STAAC ;
DR   Q99X73, PHNC_STAAM ;  Q7A848, PHNC_STAAN ;  Q6GKG3, PHNC_STAAR ;
DR   Q6GCY2, PHNC_STAAS ;  Q7A1Z1, PHNC_STAAW ;  Q5HKQ8, PHNC_STAEQ ;
DR   Q8CMU4, PHNC_STAES ;  Q4L9P7, PHNC_STAHJ ;  Q49XC6, PHNC_STAS1 ;
DR   Q3AKM8, PHNC_SYNSC ;  Q31DV4, PHNC_THICR ;  Q3SGJ8, PHNC_THIDA ;
DR   Q73P71, PHNC_TREDE ;  Q7M8M4, PHNC_WOLSU ;  Q1C9L0, PHNC_YERPA ;
DR   Q8ZGU5, PHNC_YERPE ;  Q1CFV9, PHNC_YERPN ;  Q66D26, PHNC_YERPS ;
//
ID   3.6.3.29
DE   Molybdate-transporting ATPase.
CA   ATP + H(2)O + molybdate(Out) = ADP + phosphate + molybdate(In).
CC   -!- A bacterial enzyme that imports molybdate anions.
PR   PROSITE; PDOC00185;
DR   P37732, MODC1_AZOVI;  Q89TQ9, MODC1_BRAJA;  Q44538, MODC2_AZOVI;
DR   Q89EW7, MODC2_BRAJA;  Q8UCD5, MODC_AGRT5 ;  Q0VQ44, MODC_ALCBS ;
DR   Q5P4W2, MODC_AROAE ;  Q7WP62, MODC_BORBR ;  Q7W1F4, MODC_BORPA ;
DR   Q7VUJ5, MODC_BORPE ;  Q2YIN5, MODC_BRUA2 ;  Q579Z3, MODC_BRUAB ;
DR   Q8YE15, MODC_BRUME ;  Q8FXI7, MODC_BRUSU ;  Q47CB7, MODC_DECAR ;
DR   Q8X4V7, MODC_ECO57 ;  Q0TJT5, MODC_ECOL5 ;  Q8FJR4, MODC_ECOL6 ;
DR   P09833, MODC_ECOLI ;  Q1REG5, MODC_ECOUT ;  Q6D7D0, MODC_ERWCT ;
DR   Q0BQ80, MODC_GRABC ;  Q7VKP7, MODC_HAEDU ;  Q4QJQ0, MODC_HAEI8 ;
DR   P45321, MODC_HAEIN ;  Q2SJB5, MODC_HAHCH ;  Q2W1R8, MODC_MAGSA ;
DR   Q65SW3, MODC_MANSM ;  Q608V9, MODC_METCA ;  P95155, MODC_MYCTU ;
DR   Q9CMS0, MODC_PASMU ;  Q7N6R3, MODC_PHOLL ;  Q6LHL2, MODC_PHOPR ;
DR   Q48J29, MODC_PSE14 ;  Q9I2N4, MODC_PSEAE ;  Q4KB64, MODC_PSEF5 ;
DR   Q3KC21, MODC_PSEPF ;  Q88G95, MODC_PSEPK ;  Q881C1, MODC_PSESM ;
DR   Q4ZSS5, MODC_PSEU2 ;  Q2K2X0, MODC_RHIEC ;  Q1MA70, MODC_RHIL3 ;
DR   Q98KI3, MODC_RHILO ;  Q92LU2, MODC_RHIME ;  Q08381, MODC_RHOCA ;
DR   Q21UI2, MODC_RHOFD ;  Q2J1U0, MODC_RHOP2 ;  Q6N0P7, MODC_RHOPA ;
DR   Q21BF6, MODC_RHOPB ;  Q13CI6, MODC_RHOPS ;  Q2RWI9, MODC_RHORT ;
DR   Q21GS5, MODC_SACD2 ;  Q57RH4, MODC_SALCH ;  Q5PG54, MODC_SALPA ;
DR   Q8Z8A4, MODC_SALTI ;  Q8ZQR6, MODC_SALTY ;  Q8EAN3, MODC_SHEON ;
DR   Q0HFA0, MODC_SHESM ;  Q0HYN8, MODC_SHESR ;  Q324F4, MODC_SHIBS ;
DR   Q32IG0, MODC_SHIDS ;  P59738, MODC_SHIFL ;  Q3Z445, MODC_SHISS ;
DR   Q3SJC6, MODC_THIDA ;  Q9KLL9, MODC_VIBCH ;  Q5E0T4, MODC_VIBF1 ;
DR   Q87HN4, MODC_VIBPA ;  Q8D740, MODC_VIBVU ;  Q7ME63, MODC_VIBVY ;
DR   Q1C951, MODC_YERPA ;  Q8ZGX6, MODC_YERPE ;  Q1CFP9, MODC_YERPN ;
DR   Q66D71, MODC_YERPS ;
//
ID   3.6.3.30
DE   Fe(3+)-transporting ATPase.
CA   ATP + H(2)O + Fe(3+)(Out) = ADP + phosphate + Fe(3+)(In).
CC   -!- A bacterial enzyme that imports ferric cations.
PR   PROSITE; PDOC00185;
DR   Q6D734, FBPC1_ERWCT;  P44531, FBPC1_HAEIN;  Q92WJ0, FBPC1_RHIME;
DR   Q0SBZ1, FBPC1_RHOSR;  Q6D2F6, FBPC2_ERWCT;  P44513, FBPC2_HAEIN;
DR   Q92UV5, FBPC2_RHIME;  Q0S0Z3, FBPC2_RHOSR;  Q0RYP7, FBPC3_RHOSR;
DR   Q57293, FBPC_ACTPL ;  Q8U6M1, FBPC_AGRT5 ;  Q2YKX3, FBPC_BRUA2 ;
DR   Q578K3, FBPC_BRUAB ;  Q8YCG3, FBPC_BRUME ;  Q8FVV5, FBPC_BRUSU ;
DR   Q7AH43, FBPC_ECO57 ;  P37009, FBPC_ECOLI ;  Q8RGC8, FBPC_FUSNN ;
DR   Q4QP85, FBPC_HAEI8 ;  Q0I2Z4, FBPC_HAES1 ;  Q65S66, FBPC_MANSM ;
DR   Q5FA19, FBPC_NEIG1 ;  Q50966, FBPC_NEIGO ;  Q9JVH1, FBPC_NEIMA ;
DR   Q4W575, FBPC_NEIMB ;  Q9CM80, FBPC_PASMU ;  Q7N8B9, FBPC_PHOLL ;
DR   Q6LKD4, FBPC_PHOPR ;  Q4KC87, FBPC_PSEF5 ;  Q3KCC5, FBPC_PSEPF ;
DR   Q2K8C8, FBPC_RHIEC ;  Q98G43, FBPC_RHILO ;  P21410, FBPC_SERMA ;
DR   Q82JY6, FBPC_STRAW ;  O86751, FBPC_STRCO ;  Q9KLQ5, FBPC_VIBCH ;
DR   Q56927, FBPC_YEREN ;  Q1C607, FBPC_YERPA ;  Q8ZCM2, FBPC_YERPE ;
DR   Q1CJS9, FBPC_YERPN ;  Q668Q3, FBPC_YERPS ;
//
ID   3.6.3.31
DE   Polyamine-transporting ATPase.
CA   ATP + H(2)O + polyamine(Out) = ADP + phosphate + polyamine(In).
CC   -!- A bacterial enzyme that imports putrescine and spermidine.
PR   PROSITE; PDOC00185;
DR   Q9I6T2, POTA1_PSEAE;  Q9HY19, POTA2_PSEAE;  A0LUE6, POTA_ACIC1 ;
DR   O85818, POTA_AGGAC ;  Q3MAR5, POTA_ANAVT ;  Q2NK31, POTA_AYWBP ;
DR   A0RBB0, POTA_BACAH ;  Q81TH8, POTA_BACAN ;  Q73BM0, POTA_BACC1 ;
DR   Q81GC1, POTA_BACCR ;  Q63E84, POTA_BACCZ ;  Q5LBT4, POTA_BACFN ;
DR   Q64SQ6, POTA_BACFR ;  Q6HLQ9, POTA_BACHK ;  Q8A883, POTA_BACTN ;
DR   Q0SML1, POTA_BORAP ;  O51587, POTA_BORBU ;  Q660M8, POTA_BORGA ;
DR   Q7NQN5, POTA_CHRVO ;  Q97KS6, POTA_CLOAB ;  Q18AM3, POTA_CLOD6 ;
DR   A0PY57, POTA_CLONN ;  Q0TNZ3, POTA_CLOP1 ;  Q8XIZ5, POTA_CLOPE ;
DR   Q0SRL2, POTA_CLOPS ;  A3DDF6, POTA_CLOTH ;  Q30V33, POTA_DESDG ;
DR   Q24XJ2, POTA_DESHY ;  Q72FW5, POTA_DESVH ;  P69876, POTA_ECO57 ;
DR   A1AA20, POTA_ECOK1 ;  Q0TIU8, POTA_ECOL5 ;  P69875, POTA_ECOL6 ;
DR   P69874, POTA_ECOLI ;  Q1RD28, POTA_ECOUT ;  Q830W6, POTA_ENTFA ;
DR   Q6D4E2, POTA_ERWCT ;  Q0RAT5, POTA_FRAAA ;  Q8RI39, POTA_FUSNN ;
DR   Q5L222, POTA_GEOKA ;  Q7VNG4, POTA_HAEDU ;  Q4QK57, POTA_HAEI8 ;
DR   P45171, POTA_HAEIN ;  Q0I3Y9, POTA_HAES1 ;  Q2SJY7, POTA_HAHCH ;
DR   Q5FL41, POTA_LACAC ;  Q03PF2, POTA_LACBA ;  Q03AH0, POTA_LACC3 ;
DR   Q1GB17, POTA_LACDA ;  Q04BG2, POTA_LACDB ;  Q042G7, POTA_LACGA ;
DR   Q74K65, POTA_LACJO ;  Q9CGD4, POTA_LACLA ;  Q02Z10, POTA_LACLS ;
DR   Q88ZJ6, POTA_LACPL ;  Q1WVI7, POTA_LACS1 ;  Q38VW6, POTA_LACSS ;
DR   Q1MQ44, POTA_LAWIP ;  Q5X627, POTA_LEGPA ;  Q5ZWE4, POTA_LEGPH ;
DR   Q5WXF0, POTA_LEGPL ;  Q03ZQ0, POTA_LEUMM ;  Q92DL6, POTA_LISIN ;
DR   Q722B1, POTA_LISMF ;  Q8Y8T6, POTA_LISMO ;  A0AGP9, POTA_LISW6 ;
DR   Q65UE1, POTA_MANSM ;  A1TXH7, POTA_MARAV ;  Q6F0V4, POTA_MESFL ;
DR   Q60AI1, POTA_METCA ;  Q2SSS4, POTA_MYCCT ;  Q7NB11, POTA_MYCGA ;
DR   P47288, POTA_MYCGE ;  Q5ZZZ7, POTA_MYCH2 ;  Q4A7I1, POTA_MYCH7 ;
DR   Q4A9E1, POTA_MYCHJ ;  Q6KIP2, POTA_MYCMO ;  Q6MU19, POTA_MYCMS ;
DR   Q8EUR3, POTA_MYCPE ;  P75059, POTA_MYCPN ;  Q98QE1, POTA_MYCPU ;
DR   Q4A5Q4, POTA_MYCS5 ;  A1UG51, POTA_MYCSK ;  Q1B8V9, POTA_MYCSS ;
DR   A1TAI4, POTA_MYCVP ;  Q0AGF4, POTA_NITEC ;  Q82TL6, POTA_NITEU ;
DR   Q2YAD6, POTA_NITMU ;  Q8YM92, POTA_NOSS1 ;  Q8ELR4, POTA_OCEIH ;
DR   Q04G50, POTA_OENOB ;  Q6YPR6, POTA_ONYPE ;  Q6MCV4, POTA_PARUW ;
DR   Q9CP06, POTA_PASMU ;  Q6LR20, POTA_PHOPR ;  Q02R79, POTA_PSEAB ;
DR   Q4K681, POTA_PSEF5 ;  Q3KBH4, POTA_PSEPF ;  Q1QE80, POTA_PSYCK ;
DR   Q98HF7, POTA_RHILO ;  Q160M2, POTA_ROSDO ;  Q1AS06, POTA_RUBXD ;
DR   Q57QC8, POTA_SALCH ;  Q5PMK1, POTA_SALPA ;  Q8Z7H7, POTA_SALTI ;
DR   P40790, POTA_SALTY ;  Q31ZK0, POTA_SHIBS ;  Q32EY4, POTA_SHIDS ;
DR   Q0T5R2, POTA_SHIF8 ;  P69877, POTA_SHIFL ;  Q3Z2Z3, POTA_SHISS ;
DR   Q5LT05, POTA_SILPO ;  Q1GIE5, POTA_SILST ;  Q14Q07, POTA_SPICI ;
DR   Q2FHY1, POTA_STAA3 ;  Q2G2A7, POTA_STAA8 ;  Q2YX74, POTA_STAAB ;
DR   Q5HGY5, POTA_STAAC ;  Q99V03, POTA_STAAM ;  Q7A679, POTA_STAAN ;
DR   Q6GHY6, POTA_STAAR ;  Q6GAB5, POTA_STAAS ;  Q7A169, POTA_STAAW ;
DR   Q5HQ70, POTA_STAEQ ;  Q8CPN0, POTA_STAES ;  Q4L5B3, POTA_STAHJ ;
DR   Q49WM4, POTA_STAS1 ;  Q3K0Y6, POTA_STRA1 ;  Q8E554, POTA_STRA3 ;
DR   Q8DZJ0, POTA_STRA5 ;  Q8DUF7, POTA_STRMU ;  Q99ZS8, POTA_STRP1 ;
DR   Q04JW0, POTA_STRP2 ;  P0CZ34, POTA_STRP3 ;  Q5XCA4, POTA_STRP6 ;
DR   Q7CN92, POTA_STRP8 ;  Q1JBV6, POTA_STRPB ;  Q1JLT7, POTA_STRPC ;
DR   Q1JGY7, POTA_STRPD ;  Q1J6Q6, POTA_STRPF ;  Q48TP4, POTA_STRPM ;
DR   Q97Q42, POTA_STRPN ;  P0CZ35, POTA_STRPQ ;  Q8DPC2, POTA_STRR6 ;
DR   A3CMQ7, POTA_STRSV ;  Q5LYN4, POTA_STRT1 ;  Q5M397, POTA_STRT2 ;
DR   Q03JH1, POTA_STRTD ;  Q47T99, POTA_THEFY ;  Q9X196, POTA_THEMA ;
DR   O83658, POTA_TREPA ;  Q110U3, POTA_TRIEI ;  Q9PR37, POTA_UREPA ;
DR   Q9KS33, POTA_VIBCH ;  Q5E586, POTA_VIBF1 ;  Q87PH3, POTA_VIBPA ;
DR   Q8D9J4, POTA_VIBVU ;  Q7MKU3, POTA_VIBVY ;
//
ID   3.6.3.32
DE   Quaternary-amine-transporting ATPase.
CA   ATP + H(2)O + quaternary amine(Out) = ADP + phosphate + quaternary
CA   amine(In).
CC   -!- A bacterial enzyme that imports betaine and glycine.
PR   PROSITE; PDOC00185;
DR   P46920, OPUAA_BACSU;  Q9KIF7, OPUAA_LACLA;
//
ID   3.6.3.33
DE   Vitamin B12-transporting ATPase.
CA   ATP + H(2)O + vitamin B12(Out) = ADP + phosphate + vitamin B12(In).
CC   -!- A bacterial enzyme that imports cobalamin derivatives.
PR   PROSITE; PDOC00185;
DR   B0R5G4, BTUDA_HALS3;  Q9HQ18, BTUDA_HALSA;  A8AHA1, BTUD_CITK8 ;
DR   A7ZMH7, BTUD_ECO24 ;  B7US48, BTUD_ECO27 ;  B7MAS0, BTUD_ECO45 ;
DR   B7L6I2, BTUD_ECO55 ;  Q8X5W0, BTUD_ECO57 ;  B5YPZ7, BTUD_ECO5E ;
DR   B7NTS2, BTUD_ECO7I ;  B7MV91, BTUD_ECO81 ;  B7M1B8, BTUD_ECO8A ;
DR   C4ZYH1, BTUD_ECOBW ;  B1XG16, BTUD_ECODH ;  A8A0Q1, BTUD_ECOHS ;
DR   A1ABP5, BTUD_ECOK1 ;  Q0THB9, BTUD_ECOL5 ;  Q8FH28, BTUD_ECOL6 ;
DR   B1IPL8, BTUD_ECOLC ;  P06611, BTUD_ECOLI ;  B7N547, BTUD_ECOLU ;
DR   B6I8R4, BTUD_ECOSE ;  B1LE21, BTUD_ECOSM ;  Q1RB86, BTUD_ECOUT ;
DR   Q6D654, BTUD_ERWCT ;  Q7N3Q4, BTUD_PHOLL ;  Q6LQ77, BTUD_PHOPR ;
DR   Q57PU4, BTUD_SALCH ;  B5FJ99, BTUD_SALDC ;  B5QVV9, BTUD_SALEP ;
DR   B4TGI0, BTUD_SALHS ;  Q5PH81, BTUD_SALPA ;  B5BA33, BTUD_SALPK ;
DR   P63352, BTUD_SALTI ;  P63351, BTUD_SALTY ;  B2U358, BTUD_SHIB3 ;
DR   Q321G6, BTUD_SHIBS ;  Q32FJ0, BTUD_SHIDS ;  Q0T4R9, BTUD_SHIF8 ;
DR   Q7C1M3, BTUD_SHIFL ;  Q3Z257, BTUD_SHISS ;  A5F1V0, BTUD_VIBC3 ;
DR   Q9KSL1, BTUD_VIBCH ;  C3LLU1, BTUD_VIBCM ;  A7MVV6, BTUD_VIBHB ;
DR   Q87Q38, BTUD_VIBPA ;  B7VPD0, BTUD_VIBSL ;  Q8D928, BTUD_VIBVU ;
DR   Q7MLE6, BTUD_VIBVY ;  A1JPQ1, BTUD_YERE8 ;  Q8ZDX6, BTUD_YERPE ;
DR   Q66A01, BTUD_YERPS ;
//
ID   3.6.3.34
DE   Iron-chelate-transporting ATPase.
CA   ATP + H(2)O + iron chelate(Out) = ADP + phosphate + iron chelate(In).
CC   -!- A bacterial enzyme that imports Fe-enterobactin, Fe-dicitrate,
CC       Fe-hydroxamate and other siderophores.
PR   PROSITE; PDOC00185;
DR   P49938, FHUC_BACSU ;  P07821, FHUC_ECOLI ;
//
ID   3.6.3.35
DE   Manganese-transporting ATPase.
AN   ABC-type manganese permease complex.
CA   ATP + H(2)O + Mn(2+)(Out) = ADP + phosphate + Mn(2+)(In).
CC   -!- A bacterial enzyme that imports Mn(2+), Zn(2+) and iron chelates.
PR   PROSITE; PDOC00185;
//
ID   3.6.3.36
DE   Taurine-transporting ATPase.
CA   ATP + H(2)O + taurine(Out) = ADP + phosphate + taurine(In).
CC   -!- A bacterial enzyme that imports taurine.
PR   PROSITE; PDOC00185;
DR   Q146E7, TAUB1_BURXL;  Q13KX9, TAUB2_BURXL;  Q13IS7, TAUB3_BURXL;
DR   Q1BT84, TAUB_BURCA ;  A0KAV6, TAUB_BURCH ;  Q62AW4, TAUB_BURMA ;
DR   Q3JKX3, TAUB_BURP1 ;  Q63JZ3, TAUB_BURPS ;  Q39CJ6, TAUB_BURS3 ;
DR   Q2T751, TAUB_BURTA ;  Q7NU46, TAUB_CHRVO ;  Q0K2U3, TAUB_CUPNH ;
DR   Q471U2, TAUB_CUPPJ ;  Q8X5I6, TAUB_ECO57 ;  Q0TKS1, TAUB_ECOL5 ;
DR   Q8FKF5, TAUB_ECOL6 ;  Q47538, TAUB_ECOLI ;  Q1RFH8, TAUB_ECOUT ;
DR   Q28K97, TAUB_JANSC ;  Q6RH47, TAUB_PARPN ;  Q4FMG5, TAUB_PELUB ;
DR   Q48C94, TAUB_PSE14 ;  Q02SA6, TAUB_PSEAB ;  Q9HX79, TAUB_PSEAE ;
DR   Q1IGM2, TAUB_PSEE4 ;  Q4KK16, TAUB_PSEF5 ;  Q3KJQ7, TAUB_PSEPF ;
DR   Q88RA1, TAUB_PSEPK ;  Q8KZR4, TAUB_PSEPU ;  Q87UH7, TAUB_PSESM ;
DR   Q2K164, TAUB_RHIEC ;  Q1M7R4, TAUB_RHIL3 ;  Q98DW6, TAUB_RHILO ;
DR   Q92UX0, TAUB_RHIME ;  Q6W2B1, TAUB_RHISN ;  Q16BJ3, TAUB_ROSDO ;
DR   Q325N3, TAUB_SHIBS ;  Q32IZ6, TAUB_SHIDS ;  Q0T7M2, TAUB_SHIF8 ;
DR   Q83MA0, TAUB_SHIFL ;  Q3Z542, TAUB_SHISS ;  Q5LVM5, TAUB_SILPO ;
DR   Q1C2S1, TAUB_YERPA ;  Q8ZJD0, TAUB_YERPE ;  Q1CCR9, TAUB_YERPN ;
DR   Q664P8, TAUB_YERPS ;
//
ID   3.6.3.37
DE   Guanine-transporting ATPase.
CA   ATP + H(2)O + guanine(Out) = ADP + phosphate + guanine(In).
CC   -!- A eukaryotic enzyme that imports guanine and tryptophan (it contains
CC       a single ATP-binding site).
PR   PROSITE; PDOC00185;
//
ID   3.6.3.38
DE   Capsular-polysaccharide-transporting ATPase.
CA   ATP + H(2)O + capsular polysaccharide(In) = ADP + phosphate + capsular
CA   polysaccharide(Out).
CC   -!- An enzyme that exports capsular polysaccharide from Gram-negative
CC       bacteria.
PR   PROSITE; PDOC00185;
DR   P57013, CTRD_NEIMA ;  P32016, CTRD_NEIMB ;
//
ID   3.6.3.39
DE   Lipopolysaccharide-transporting ATPase.
CA   ATP + H(2)O + lipopolysaccharide(In) = ADP + phosphate +
CA   lipopolysaccharide(Out).
CC   -!- Enzymes of Gram-negative bacteria that export lipo-oligosaccharides
CC       and lipopolysaccharides.
PR   PROSITE; PDOC00185;
//
ID   3.6.3.40
DE   Teichoic-acid-transporting ATPase.
CA   ATP + H(2)O + teichoic acid(In) = ADP + phosphate + teichoic acid(Out).
CC   -!- An enzyme found in Gram-positive bacteria that exports teichoic acid.
PR   PROSITE; PDOC00185;
DR   Q81K31, TAGH_BACAN ;  Q630Y3, TAGH_BACCZ ;  Q65E84, TAGH_BACLD ;
DR   Q5WCL2, TAGH_BACSK ;  P42954, TAGH_BACSU ;  Q831L8, TAGH_ENTFA ;
DR   Q03SI5, TAGH_LACBA ;  Q9CH26, TAGH_LACLA ;  Q88ZH4, TAGH_LACPL ;
DR   Q92CV8, TAGH_LISIN ;  Q720Z5, TAGH_LISMF ;  Q8Y843, TAGH_LISMO ;
DR   Q2FJ01, TAGH_STAA3 ;  Q2G2L1, TAGH_STAA8 ;  Q2YSU3, TAGH_STAAB ;
DR   Q5HI31, TAGH_STAAC ;  Q7A2W2, TAGH_STAAM ;  Q7A713, TAGH_STAAN ;
DR   Q6GJ33, TAGH_STAAR ;  Q6GBJ3, TAGH_STAAS ;  Q9LC44, TAGH_STAAU ;
DR   Q8NXS6, TAGH_STAAW ;  Q5HR97, TAGH_STAEQ ;  Q8CTM4, TAGH_STAES ;
DR   Q4L459, TAGH_STAHJ ;  Q49VI3, TAGH_STAS1 ;
//
ID   3.6.3.41
DE   Heme-transporting ATPase.
CA   ATP + H(2)O + heme(In) = ADP + phosphate + heme(Out).
CC   -!- An enzyme found in Gram-negative bacteria that exports heme.
PR   PROSITE; PDOC00185;
DR   Q9C8T1, AB1I_ARATH ;  Q1LKR4, CCMA1_RALME;  Q57M97, CCMA1_SALCH;
DR   Q5PI55, CCMA1_SALPA;  Q8ZKZ9, CCMA1_SALTY;  Q8GQ92, CCMA2_PSEAE;
DR   Q1LFZ8, CCMA2_RALME;  Q5PKT6, CCMA2_SALPA;  P61378, CCMA2_SALTY;
DR   Q57I19, CCMAE_SALCH;  Q8UC12, CCMA_AGRT5 ;  Q0VR80, CCMA_ALCBS ;
DR   Q0A808, CCMA_ALHEH ;  Q5PBP5, CCMA_ANAMM ;  Q5P3L0, CCMA_AROAE ;
DR   Q6G529, CCMA_BARHE ;  Q6G0V9, CCMA_BARQU ;  Q7WIP8, CCMA_BORBR ;
DR   Q7W736, CCMA_BORPA ;  P30963, CCMA_BRAJA ;  Q2YNU0, CCMA_BRUA2 ;
DR   Q57FS7, CCMA_BRUAB ;  Q8YEM5, CCMA_BRUME ;  Q8G358, CCMA_BRUSU ;
DR   Q13I12, CCMA_BURXL ;  Q9A298, CCMA_CAUCR ;  Q487I2, CCMA_COLP3 ;
DR   Q7WXC1, CCMA_CUPNH ;  Q46RX0, CCMA_CUPPJ ;  Q478L3, CCMA_DECAR ;
DR   Q8XE58, CCMA_ECO57 ;  Q0TFP1, CCMA_ECOL5 ;  Q8FFR2, CCMA_ECOL6 ;
DR   P33931, CCMA_ECOLI ;  Q1R9L8, CCMA_ECOUT ;  Q6D606, CCMA_ERWCT ;
DR   Q5FQN4, CCMA_GLUOX ;  Q0BV49, CCMA_GRABC ;  Q7VN12, CCMA_HAEDU ;
DR   Q4QLJ9, CCMA_HAEI8 ;  P45032, CCMA_HAEIN ;  Q0I2G0, CCMA_HAES1 ;
DR   Q2SE49, CCMA_HAHCH ;  Q0BWF7, CCMA_HYPNA ;  Q5QZP7, CCMA_IDILO ;
DR   Q28NZ8, CCMA_JANSC ;  Q5X6P7, CCMA_LEGPA ;  Q5ZX76, CCMA_LEGPH ;
DR   Q5WY52, CCMA_LEGPL ;  Q8RPP4, CCMA_LEGPN ;  Q2VZJ1, CCMA_MAGSA ;
DR   Q65V02, CCMA_MANSM ;  Q0AKQ2, CCMA_MARMM ;  Q11CZ6, CCMA_MESSB ;
DR   Q60AB3, CCMA_METCA ;  Q82WC8, CCMA_NITEU ;  Q1QR47, CCMA_NITHX ;
DR   Q2Y9Q1, CCMA_NITMU ;  Q3JCI7, CCMA_NITOC ;  Q3SVV2, CCMA_NITWN ;
DR   Q2G9A9, CCMA_NOVAD ;  Q9Z651, CCMA_PANCI ;  P52218, CCMA_PARDP ;
DR   Q9CPN2, CCMA_PASMU ;  Q6LTL7, CCMA_PHOPR ;  Q48GL0, CCMA_PSE14 ;
DR   Q9I3N7, CCMA_PSEAE ;  Q4KG27, CCMA_PSEF5 ;  Q3KFY6, CCMA_PSEPF ;
DR   P95487, CCMA_PSEPG ;  Q88EX5, CCMA_PSEPK ;  Q87Z03, CCMA_PSESM ;
DR   Q4ZQZ7, CCMA_PSEU2 ;  O21280, CCMA_RECAM ;  Q2K396, CCMA_RHIEC ;
DR   Q52733, CCMA_RHIET ;  Q1MAL7, CCMA_RHIL3 ;  Q98EA4, CCMA_RHILO ;
DR   Q92L55, CCMA_RHIME ;  P29959, CCMA_RHOCB ;  Q21QL9, CCMA_RHOFD ;
DR   Q2J3F7, CCMA_RHOP2 ;  Q6NDA6, CCMA_RHOPA ;  Q21CV6, CCMA_RHOPB ;
DR   Q13DS7, CCMA_RHOPS ;  Q2RYF0, CCMA_RHORT ;  O33570, CCMA_RHOS4 ;
DR   Q1RKE4, CCMA_RICBR ;  Q92G95, CCMA_RICCN ;  Q4UK25, CCMA_RICFE ;
DR   Q9ZCF9, CCMA_RICPR ;  Q68VV5, CCMA_RICTY ;  Q166I9, CCMA_ROSDO ;
DR   Q21JK3, CCMA_SACD2 ;  P61377, CCMA_SALTI ;  Q12I82, CCMA_SHEDO ;
DR   Q089M3, CCMA_SHEFN ;  Q8EK40, CCMA_SHEON ;  Q0HNQ5, CCMA_SHESM ;
DR   Q0I074, CCMA_SHESR ;  Q31Z24, CCMA_SHIBS ;  Q32I01, CCMA_SHIDS ;
DR   Q83KD5, CCMA_SHIFL ;  Q3Z006, CCMA_SHISS ;  Q5LR15, CCMA_SILPO ;
DR   Q1GHY4, CCMA_SILST ;  Q2NSG3, CCMA_SODGM ;  Q1GS38, CCMA_SPHAL ;
DR   Q9KQE3, CCMA_VIBCH ;  Q5E3S7, CCMA_VIBF1 ;  Q87MK8, CCMA_VIBPA ;
DR   Q8DB62, CCMA_VIBVU ;  Q7MIR0, CCMA_VIBVY ;  Q73HX8, CCMA_WOLPM ;
DR   Q8PK53, CCMA_XANAC ;  Q3BSL0, CCMA_XANC5 ;  Q4UVG2, CCMA_XANC8 ;
DR   Q8P8M1, CCMA_XANCP ;  Q2P3U8, CCMA_XANOM ;  Q5H0W2, CCMA_XANOR ;
DR   Q9PAP0, CCMA_XYLFA ;  Q87BH8, CCMA_XYLFT ;  Q1C647, CCMA_YERPA ;
DR   Q8ZD58, CCMA_YERPE ;  Q1CHI9, CCMA_YERPN ;  Q668T8, CCMA_YERPS ;
DR   Q5NQX0, CCMA_ZYMMO ;
//
ID   3.6.3.42
DE   Beta-glucan-transporting ATPase.
CA   ATP + H(2)O + beta-glucan(In) = ADP + phosphate + beta-glucan(Out).
CC   -!- An enzyme found in Gram-negative bacteria that exports beta-glucan.
PR   PROSITE; PDOC00185;
DR   P0A2V0, NDVA_AGRT5 ;  Q71ED1, NDVA_AGRVI ;  P70864, NDVA_BARBA ;
DR   A1USS5, NDVA_BARBK ;  Q6G2Z5, NDVA_BARHE ;  Q6FZF2, NDVA_BARQU ;
DR   Q89UT8, NDVA_BRAJA ;  Q2YQ73, NDVA_BRUA2 ;  P0C529, NDVA_BRUAB ;
DR   Q8YH20, NDVA_BRUME ;  Q8G0T8, NDVA_BRUSU ;  Q1QH37, NDVA_NITHX ;
DR   Q3SP57, NDVA_NITWN ;  Q2K342, NDVA_RHIEC ;  Q1MAB5, NDVA_RHIL3 ;
DR   Q983H5, NDVA_RHILO ;  P18767, NDVA_RHIME ;  P0A2V1, NDVA_RHIRD ;
DR   Q2J0F4, NDVA_RHOP2 ;  Q07QX6, NDVA_RHOP5 ;  Q6N1Y7, NDVA_RHOPA ;
DR   Q20Z38, NDVA_RHOPB ;  Q13BH6, NDVA_RHOPS ;
//
ID   3.6.3.43
DE   Peptide-transporting ATPase.
CA   ATP + H(2)O + peptide(In) = ADP + phosphate + peptide(Out).
CC   -!- A family of enzymes that exports alpha-hemolysin, cyclolysin, colicin
CC       V and siderophores from Gram-negative bacteria, and bacteriocin,
CC       subtilin, competence factor and pediocin from Gram-positive bacteria.
PR   PROSITE; PDOC00185;
PR   PROSITE; PDOC50990;
DR   Q93FH2, LKB13_PASHA;  P0C087, LKB14_PASHA;  Q93FH3, LKB16_PASHA;
DR   P16532, LKB1A_PASHA;  Q93FH6, LKB1B_PASHA;  Q93FH0, LKB2A_PASHA;
DR   Q93FG6, LKB2B_PASHA;  P0C086, LKTB7_PASHA;  P23702, LKTB_AGGAC ;
DR   Q933I3, LKTB_MANGL ;  P55122, LKTB_PASSP ;  Q933E0, LKTB_PASTR ;
DR   Q9RCG7, PAXB_PASAE ;
//
ID   3.6.3.44
DE   Xenobiotic-transporting ATPase.
AN   ATP phosphohydrolase (steroid-exporting).
AN   MDR protein.
AN   Multidrug-resistance protein.
AN   P-glycoprotein.
AN   PDR protein.
AN   Pleiotropic-drug-resistance protein.
AN   Steroid-transporting ATPase.
CA   ATP + H(2)O + xenobiotic(In) = ADP + phosphate + xenobiotic(Out).
CC   -!- Enzymes of Gram-positive bacteria and eukaryotic cells that export a
CC       number of drugs, with unusual specificity, covering various groups of
CC       unrelated substances, while ignoring some that are closely related
CC       structurally.
CC   -!- Several distinct enzymes may be present in a single eukaryotic cell.
CC   -!- Many of them transport glutathione conjugates with drugs.
CC   -!- Some also show some 'flippase' (EC 3.6.3.1) activity.
CC   -!- Formerly EC 3.6.3.45.
PR   PROSITE; PDOC00185;
DR   Q9LYS2, AB10C_ARATH;  Q9C8H1, AB11C_ARATH;  Q9C8H0, AB12C_ARATH;
DR   Q9SKX0, AB13C_ARATH;  Q9LZJ5, AB14C_ARATH;  Q7FB56, AB15C_ARATH;
DR   Q9C8G9, AB1C_ARATH ;  Q42093, AB2C_ARATH ;  Q9LK64, AB3C_ARATH ;
DR   Q7DM58, AB4C_ARATH ;  Q7GB25, AB5C_ARATH ;  Q8VZZ4, AB6C_ARATH ;
DR   Q9LK62, AB7C_ARATH ;  Q8LGU1, AB8C_ARATH ;  Q9M1C7, AB9C_ARATH ;
DR   Q9P7V2, ABC4_SCHPO ;  Q9CHL8, LMRA_LACLA ;  P97046, LMRA_LACLM ;
DR   P57551, MDLA_BUCAI ;  Q8K985, MDLA_BUCAP ;  Q89A97, MDLA_BUCBP ;
DR   P77265, MDLA_ECOLI ;  P57552, MDLB_BUCAI ;  Q8K984, MDLB_BUCAP ;
DR   Q89A96, MDLB_BUCBP ;  P0AAG7, MDLB_ECO57 ;  P0AAG6, MDLB_ECOL6 ;
DR   P0AAG5, MDLB_ECOLI ;  P34712, MDR1_CAEEL ;  P21448, MDR1_CRIGR ;
DR   P08183, MDR1_HUMAN ;  Q06034, MDR1_LEIEN ;  P06795, MDR1_MOUSE ;
DR   P43245, MDR1_RAT   ;  P21449, MDR2_CRIGR ;  P21440, MDR2_MOUSE ;
DR   Q08201, MDR2_RAT   ;  P34713, MDR3_CAEEL ;  P23174, MDR3_CRIGR ;
DR   P21439, MDR3_HUMAN ;  P21447, MDR3_MOUSE ;  Q00449, MDR49_DROME;
DR   Q00748, MDR65_DROME;  P21441, MDR_LEITA  ;  P13568, MDR_PLAFF  ;
//
ID   3.6.3.45
DE   Transferred entry: 3.6.3.44.
//
ID   3.6.3.46
DE   Cadmium-transporting ATPase.
AN   Yeast cadmium factor.
CA   ATP + H(2)O = ADP + phosphate.
CC   -!- A Saccharomyces cerevisiae enzyme that exports some heavy metals,
CC       especially Cd(2+), from the cytosol into the vacuole.
PR   PROSITE; PDOC00185;
//
ID   3.6.3.47
DE   Fatty-acyl-CoA-transporting ATPase.
CA   ATP + H(2)O + fatty acyl CoA(Cis) = ADP + phosphate + fatty acyl
CA   CoA(Trans).
CC   -!- An animal and Saccharomyces cerevisiae enzyme that transports fatty
CC       acyl CoA into and out of peroxisomes.
PR   PROSITE; PDOC00185;
DR   Q94FB9, AB1D_ARATH ;
//
ID   3.6.3.48
DE   Alpha-factor-transporting ATPase.
CA   ATP + H(2)O + alpha-factor(In) = ADP + phosphate + alpha-factor(Out).
CC   -!- A Saccharomyces cerevisiae enzyme that exports the alpha-factor sex
CC       pheromone.
PR   PROSITE; PDOC00185;
DR   P53706, HST6_CANAL ;  P12866, STE6_YEAST ;
//
ID   3.6.3.49
DE   Channel-conductance-controlling ATPase.
AN   Cystic-fibrosis membrane-conductance-regulating protein.
CA   ATP + H(2)O = ADP + phosphate.
CC   -!- An animal enzyme that is active in forming a chloride channel,
CC       the absence of which brings about cystic fibrosis.
CC   -!- It is also involved in the functioning of other transmembrane
CC       channels.
PR   PROSITE; PDOC00185;
DR   Q07DV2, CFTR_AOTNA ;  Q00PJ2, CFTR_ATEAB ;  Q09YK5, CFTR_ATEGE ;
DR   P35071, CFTR_BOVIN ;  Q2QLF9, CFTR_CALJA ;  Q2QLB4, CFTR_CALMO ;
DR   Q5U820, CFTR_CANFA ;  Q2QLC5, CFTR_CARPS ;  Q00552, CFTR_CAVPO ;
DR   Q2IBA1, CFTR_CHLAE ;  Q07DY5, CFTR_COLGU ;  Q07E42, CFTR_DASNO ;
DR   Q2QL74, CFTR_DIDMA ;  Q2IBF6, CFTR_GORGO ;  Q2QLA3, CFTR_HORSE ;
DR   P13569, CFTR_HUMAN ;  Q108U0, CFTR_LOXAF ;  Q7JII8, CFTR_MACFA ;
DR   Q7JII7, CFTR_MACFU ;  Q00553, CFTR_MACMU ;  Q9TUQ2, CFTR_MACNE ;
DR   Q2QL83, CFTR_MICMU ;  P26361, CFTR_MOUSE ;  Q09YJ4, CFTR_MUNMU ;
DR   Q07DW5, CFTR_MUNRE ;  Q07E16, CFTR_MUSPF ;  Q07DX5, CFTR_NOMLE ;
DR   Q07DZ6, CFTR_ORNAN ;  Q2QLH0, CFTR_OTOGA ;  Q2QLE5, CFTR_PANTR ;
DR   Q9TSP5, CFTR_PAPAN ;  Q6PQZ2, CFTR_PIG   ;  Q2IBE4, CFTR_PONAB ;
DR   Q00554, CFTR_RABIT ;  P34158, CFTR_RAT   ;  Q2IBB3, CFTR_RHIFE ;
DR   Q09YH0, CFTR_SAIBB ;  Q00555, CFTR_SHEEP ;  P26362, CFTR_SQUAC ;
DR   Q5D1Z7, CFTR_TRIVU ;  P26363, CFTR_XENLA ;
//
ID   3.6.3.50
DE   Protein-secreting ATPase.
CA   ATP + H(2)O = ADP + phosphate.
CC   -!- A non-phosphorylated, non-ABC (ATP-binding cassette) ATPase that is
CC       involved in protein transport.
CC   -!- There are several families of enzymes included here, e.g. ATP-
CC       hydrolyzing enzymes of the general secretory pathway (Sec or Type
CC       II), of the virulence-related secretory pathway (Type III) and of the
CC       conjugal DNA-protein transfer pathway (Type IV).
CC   -!- Type II enzymes occur in bacteria, archaea and eukaryotes, whereas
CC       type III and type IV enzymes occur in bacteria where they form
CC       components of a multi-subunit complex.
//
ID   3.6.3.51
DE   Mitochondrial protein-transporting ATPase.
CA   ATP + H(2)O = ADP + phosphate.
CC   -!- A non-phosphorylated, non-ABC (ATP-binding cassette) ATPase involved
CC       in the transport of proteins or preproteins into mitochondria using
CC       the TIM protein complex.
CC   -!- TIM is the protein transport machinery of the inner mitochondrial
CC       membrane that contains three essential Tim proteins: Tim17 and Tim23
CC       are thought to build a preprotein translocation channel while Tim44
CC       interacts transiently with the matrix heat-shock protein Hsp70 to
CC       form an ATP-driven import motor.
//
ID   3.6.3.52
DE   Chloroplast protein-transporting ATPase.
CA   ATP + H(2)O = ADP + phosphate.
CC   -!- A non-phosphorylated, non-ABC (ATP-binding cassette) ATPase that is
CC       involved in protein transport.
CC   -!- Involved in the transport of proteins or preproteins into chloroplast
CC       stroma (several ATPases may participate in this process).
//
ID   3.6.3.53
DE   Ag(+)-exporting ATPase.
CA   ATP + H(2)O + Ag(+)(In) = ADP + phosphate + Ag(+)(Out).
CC   -!- P-type ATPase that exports Ag(+) ions from pathogenic microorganisms
CC       as well as from some animal tissues.
PR   PROSITE; PDOC00139;
//
ID   3.6.3.n1
DE   Cu(+) exporting ATPase.
CA   ATP + H(2)O + Cu(+)(In) = ADP + phosphate + Cu(+)(Out).
CC   -!- A P-type ATPase that undergoes covalent phosphorylation during the
CC       transport cycle.
CC   -!- This enzyme transports Cu(+) or Ag(+), and cannot tranport the
CC       divalent ions, contrary to EC 3.6.3.4, Cu(2+)-exporting ATPase, that
CC       is specific for the divalent copper ion.
DR   O29777, COPA_ARCFU ;  O32220, COPA_BACSU ;  Q8XD24, COPA_ECO57 ;
DR   Q59385, COPA_ECOLI ;  Q8Z8S4, COPA_SALTI ;  Q8ZR95, COPA_SALTY ;
DR   A7X6S1, COPA_STAA1 ;  A6U4T8, COPA_STAA2 ;  Q2FDV0, COPA_STAA3 ;
DR   Q2FV64, COPA_STAA8 ;  A5IVY3, COPA_STAA9 ;  Q2YWA3, COPA_STAAB ;
DR   Q5HCZ3, COPA_STAAC ;  A6QK47, COPA_STAAE ;  Q99R80, COPA_STAAM ;
DR   Q7A3E6, COPA_STAAN ;  Q6GDP1, COPA_STAAR ;  Q6G6B7, COPA_STAAS ;
DR   A8Z3F8, COPA_STAAT ;  Q8NUQ9, COPA_STAAW ;  Q5HL56, COPA_STAEQ ;
DR   Q8CN02, COPA_STAES ;  Q4L970, COPA_STAHJ ;  Q4A0G1, COPA_STAS1 ;
DR   Q9KPZ7, COPA_VIBCH ;  Q8ZCA7, COPA_YERPE ;  P05425, COPB_ENTHR ;
//
ID   3.6.4.1
DE   Myosin ATPase.
AN   Actomyosin.
CA   ATP + H(2)O = ADP + phosphate.
CC   -!- Involved in muscle contraction.
CC   -!- In the absence of actin, myosin shows only low ATPase activity, which
CC       requires Ca(2+).
CC   -!- Formerly EC 3.6.1.32.
//
ID   3.6.4.2
DE   Dynein ATPase.
CA   ATP + H(2)O = ADP + phosphate.
CC   -!- A multisubunit protein complex associated with microtubules.
CC   -!- Hydrolysis of ATP provides energy for the movement of organelles
CC       (endosomes, lysosomes, mitochondria) along microtubules to the
CC       centrosome toward the microtubule's minus end.
CC   -!- It also functions in the movement of eukaryotic flagella and cilia.
CC   -!- Formerly EC 3.6.1.33.
//
ID   3.6.4.3
DE   Microtubule-severing ATPase.
AN   Katanin.
CA   ATP + H(2)O = ADP + phosphate.
CC   -!- Another member of the AAA-ATPase family, active in splitting
CC       microtubules into tubulin dimers in the centrosome.
PR   PROSITE; PDOC00572;
DR   Q5U3S1, KATL1_DANRE;  Q9BW62, KATL1_HUMAN;  Q8K0T4, KATL1_MOUSE;
DR   B4USW8, KATL1_OTOGA;  A9RA82, KATL1_PAPAN;  B7NZ88, KATL1_RABIT;
DR   Q5XIK7, KATL1_RAT  ;  B3EX35, KATL1_SORAR;  Q8IYT4, KATL2_HUMAN;
DR   Q9D3R6, KATL2_MOUSE;  Q3B8D5, KATL2_XENLA;  A0JMA9, KATL2_XENTR;
DR   Q9SEX2, KTNA1_ARATH;  Q1HGK7, KTNA1_CHICK;  Q5RII9, KTNA1_DANRE;
DR   O75449, KTNA1_HUMAN;  Q4R407, KTNA1_MACFA;  Q9WV86, KTNA1_MOUSE;
DR   Q6E0V2, KTNA1_RAT  ;  B5X3X5, KTNA1_SALSA;  O61577, KTNA1_STRPU;
DR   Q9PUL2, KTNA1_XENLA;  Q0IIR9, KTNA1_XENTR;  P34808, MEI1_CAEEL ;
DR   Q7QBW0, SPAST_ANOGA;  A2VDN5, SPAST_BOVIN;  A8QFF6, SPAST_BRUMA;
DR   A8XV40, SPAST_CAEBR;  Q8MNV0, SPAST_CAEEL;  Q5ZK92, SPAST_CHICK;
DR   Q6NW58, SPAST_DANRE;  Q54KQ7, SPAST_DICDI;  B3M301, SPAST_DROAN;
DR   B3P8A3, SPAST_DROER;  B4JII0, SPAST_DROGR;  Q8I0P1, SPAST_DROME;
DR   B4K799, SPAST_DROMO;  B4G437, SPAST_DROPE;  Q298L4, SPAST_DROPS;
DR   B4HGG6, SPAST_DROSE;  B4QSF0, SPAST_DROSI;  B4M0H8, SPAST_DROVI;
DR   B4NBP4, SPAST_DROWI;  B4PL32, SPAST_DROYA;  Q9UBP0, SPAST_HUMAN;
DR   B7PXE3, SPAST_IXOSC;  Q9QYY8, SPAST_MOUSE;  A7T395, SPAST_NEMVE;
DR   Q719N1, SPAST_PIG  ;  B2RYN7, SPAST_RAT  ;  Q6AZT2, SPAST_XENLA;
DR   Q05AS3, SPAST_XENTR;
//
ID   3.6.4.4
DE   Plus-end-directed kinesin ATPase.
AN   Kinesin.
CA   ATP + H(2)O = ADP + phosphate.
CC   -!- Microtubular motor protein, involved in organelle movement,
CC       in mitosis and meiosis.
CC   -!- In contrast to dynein, it moves along microtubules toward the plus
CC       end.
CC   -!- Also hydrolyzes GTP.
PR   PROSITE; PDOC00343;
//
ID   3.6.4.5
DE   Minus-end-directed kinesin ATPase.
CA   ATP + H(2)O = ADP + phosphate.
CC   -!- Structurally almost identical to EC 3.6.4.3 but the movement it
CC       catalyzes is toward the minus end of microtubules.
PR   PROSITE; PDOC00343;
//
ID   3.6.4.6
DE   Vesicle-fusing ATPase.
CA   ATP + H(2)O = ADP + phosphate.
CC   -!- A large family of ATP-hydrolyzing enzymes involved in the heterotypic
CC       fusion of membrane vesicles with target membranes and the homotypic
CC       fusion of various membrane compartments.
CC   -!- They belong to the AAA-type (ATPase associated with a variety of cell
CC       activities) ATPase superfamily.
CC   -!- They include peroxin, which apparently is involved in Zellweger's
CC       syndrome.
PR   PROSITE; PDOC00572;
DR   P46461, NSF1_DROME ;  P54351, NSF2_DROME ;  Q9M0Y8, NSF_ARATH  ;
DR   Q94392, NSF_CAEEL  ;  P18708, NSF_CRIGR  ;  Q75JI3, NSF_DICDI  ;
DR   P46459, NSF_HUMAN  ;  P46460, NSF_MOUSE  ;  Q5R410, NSF_PONAB  ;
DR   Q9QUL6, NSF_RAT    ;
//
ID   3.6.4.7
DE   Peroxisome-assembly ATPase.
AN   Peroxisome assembly factor-2.
CA   ATP + H(2)O = ADP + phosphate.
CC   -!- An extremely diversified group of enzymes that use the energy of ATP
CC       hydrolysis to import and assemble peroxisome components into the
CC       organelle.
CC   -!- Their molecular masses range from 25 to 600 kDa.
//
ID   3.6.4.8
DE   Proteasome ATPase.
AN   RP triphosphatase.
AN   RP triple-A protein.
CA   ATP + H(2)O = ADP + phosphate.
CC   -!- Belongs to the AAA-type superfamily and, like EC 3.6.4.5, is involved
CC       in channel gating and polypeptide unfolding before proteolysis in the
CC       proteasome.
CC   -!- Six ATPase subunits are present in the regulatory particle (RP) of
CC       26S proteasome.
PR   PROSITE; PDOC00572;
//
ID   3.6.4.9
DE   Chaperonin ATPase.
AN   Chaperonin.
CA   ATP + H(2)O = ADP + phosphate.
CC   -!- Multisubunit proteins with 2x7 (Type I, in most cells) or 2x8 (Type
CC       II, in archaea) ATP-binding sites involved in maintaining an unfolded
CC       polypeptide structure before folding or to entry into mitochondria
CC       and chloroplasts.
CC   -!- Molecular masses of subunits ranges from 10-90 kDa.
//
ID   3.6.4.10
DE   Non-chaperonin molecular chaperone ATPase.
AN   Molecular chaperone Hsc70 ATPase.
CA   ATP + H(2)O = ADP + phosphate.
CC   -!- This is a highly diverse group of enzymes that perform many functions
CC       that are similar to those of chaperonins.
CC   -!- They comprise a number of heat-shock-cognate proteins.
CC   -!- They are also active in clathrin uncoating and in the oligomerization
CC       of actin.
PR   PROSITE; PDOC00269;
//
ID   3.6.4.11
DE   Nucleoplasmin ATPase.
CA   ATP + H(2)O = ADP + phosphate.
CC   -!- An acidic nuclear protein that is active in the ATP-dependent
CC       assembly of nucleosome cores, in decondensation of sperm chromatin
CC       and in other histone-involving processes.
//
ID   3.6.4.12
DE   DNA helicase.
CA   ATP + H(2)O = ADP + phosphate.
CC   -!- DNA helicases utilize the energy from ATP hydrolysis to unwind
CC       double-stranded DNA.
CC   -!- Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8),
CC       other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both
CC       directions (14,15).
CC   -!- Some helicases unwind DNA as well as RNA (4,9).
CC   -!- May be identical with EC 3.6.4.13 (RNA helicase).
PR   PROSITE; PDOC00039;
PR   PROSITE; PDOC51192;
PR   PROSITE; PDOC51198;
PR   PROSITE; PDOC51199;
PR   PROSITE; PDOC51206;
PR   PROSITE; PDOC51413;
DR   A6TVN2, ADDA_ALKMQ ;  A8MJ41, ADDA_ALKOO ;  B7GM51, ADDA_ANOFW ;
DR   A7Z368, ADDA_BACA2 ;  A0RAX7, ADDA_BACAH ;  Q81TW1, ADDA_BACAN ;
DR   B7JDU4, ADDA_BACC0 ;  Q73C23, ADDA_BACC1 ;  B7IL84, ADDA_BACC2 ;
DR   B7HGP9, ADDA_BACC4 ;  B7HZR5, ADDA_BACC7 ;  A7GM37, ADDA_BACCN ;
DR   B9ITE9, ADDA_BACCQ ;  Q81GP9, ADDA_BACCR ;  Q63EM2, ADDA_BACCZ ;
DR   Q6HM43, ADDA_BACHK ;  Q65LJ9, ADDA_BACLD ;  A8FBR1, ADDA_BACP2 ;
DR   P23478, ADDA_BACSU ;  A9VJ02, ADDA_BACWK ;  Q3AA35, ADDA_CARHZ ;
DR   Q97GV3, ADDA_CLOAB ;  A7FPG0, ADDA_CLOB1 ;  C3L047, ADDA_CLOB6 ;
DR   A6LPC4, ADDA_CLOB8 ;  B2UX57, ADDA_CLOBA ;  B2THC8, ADDA_CLOBB ;
DR   A5HYY0, ADDA_CLOBH ;  C1FSA8, ADDA_CLOBJ ;  B1IEN0, ADDA_CLOBK ;
DR   A7GAJ8, ADDA_CLOBL ;  B1KUZ8, ADDA_CLOBM ;  B8I2Y2, ADDA_CLOCE ;
DR   Q18AN9, ADDA_CLOD6 ;  B9DZK4, ADDA_CLOK1 ;  A5N628, ADDA_CLOK5 ;
DR   A0PY67, ADDA_CLONN ;  Q0TV46, ADDA_CLOP1 ;  Q8XPE2, ADDA_CLOPE ;
DR   A9KTE6, ADDA_CLOPH ;  Q0SWW4, ADDA_CLOPS ;  A3DH19, ADDA_CLOTH ;
DR   B1I493, ADDA_DESAP ;  B8FXD7, ADDA_DESHD ;  Q24WW8, ADDA_DESHY ;
DR   A4J4E3, ADDA_DESRM ;  Q836J8, ADDA_ENTFA ;  B1YKM8, ADDA_EXIS2 ;
DR   Q5L263, ADDA_GEOKA ;  A4IKW7, ADDA_GEOTN ;  B0TDI0, ADDA_HELMI ;
DR   Q5FJX0, ADDA_LACAC ;  Q03NA7, ADDA_LACBA ;  Q038V7, ADDA_LACC3 ;
DR   B3WEJ1, ADDA_LACCB ;  Q1GAA9, ADDA_LACDA ;  Q04AN7, ADDA_LACDB ;
DR   B2GEY4, ADDA_LACF3 ;  Q043G6, ADDA_LACGA ;  A8YVK0, ADDA_LACH4 ;
DR   Q74JA6, ADDA_LACJO ;  Q9CJI9, ADDA_LACLA ;  A2RH77, ADDA_LACLM ;
DR   Q033I1, ADDA_LACLS ;  Q88U41, ADDA_LACPL ;  A5VHK2, ADDA_LACRD ;
DR   B2G532, ADDA_LACRJ ;  Q1WRS0, ADDA_LACS1 ;  Q38X69, ADDA_LACSS ;
DR   B1MZM2, ADDA_LEUCK ;  Q03W49, ADDA_LEUMM ;  Q929A9, ADDA_LISIN ;
DR   Q71X99, ADDA_LISMF ;  B8DF44, ADDA_LISMH ;  Q8Y511, ADDA_LISMO ;
DR   A0AL18, ADDA_LISW6 ;  B1HN90, ADDA_LYSSC ;  Q2RL77, ADDA_MOOTA ;
DR   B2A610, ADDA_NATTJ ;  Q8ERW5, ADDA_OCEIH ;  Q04GY7, ADDA_OENOB ;
DR   Q03D71, ADDA_PEDPA ;  A5D1P3, ADDA_PELTS ;  A7X0I2, ADDA_STAA1 ;
DR   A6U074, ADDA_STAA2 ;  Q2FIA8, ADDA_STAA3 ;  Q2FZT5, ADDA_STAA8 ;
DR   A5IRE5, ADDA_STAA9 ;  Q2YWW4, ADDA_STAAB ;  Q5HHB7, ADDA_STAAC ;
DR   A6QFH8, ADDA_STAAE ;  Q99VC3, ADDA_STAAM ;  Q7A6H4, ADDA_STAAN ;
DR   Q6GIC1, ADDA_STAAR ;  Q6GAV9, ADDA_STAAS ;  A8Z073, ADDA_STAAT ;
DR   Q8NXE9, ADDA_STAAW ;  B9DIS2, ADDA_STACT ;  Q5HQJ4, ADDA_STAEQ ;
DR   Q8CPT9, ADDA_STAES ;  Q4L4Y3, ADDA_STAHJ ;  Q49WA6, ADDA_STAS1 ;
DR   Q3K1I4, ADDA_STRA1 ;  Q8E5T9, ADDA_STRA3 ;  Q8E061, ADDA_STRA5 ;
DR   B4U2H1, ADDA_STREM ;  A8AY33, ADDA_STRGC ;  Q8DT76, ADDA_STRMU ;
DR   Q9A0H3, ADDA_STRP1 ;  Q04KF8, ADDA_STRP2 ;  P0CZ52, ADDA_STRP3 ;
DR   B5E4P5, ADDA_STRP4 ;  Q5XCW6, ADDA_STRP6 ;  Q8P1J2, ADDA_STRP8 ;
DR   Q1JCJ8, ADDA_STRPB ;  Q1JMH5, ADDA_STRPC ;  Q1JHM1, ADDA_STRPD ;
DR   Q1J7E4, ADDA_STRPF ;  A2RFA8, ADDA_STRPG ;  B1IBR6, ADDA_STRPI ;
DR   B8ZQ32, ADDA_STRPJ ;  Q48UB8, ADDA_STRPM ;  Q97QP9, ADDA_STRPN ;
DR   P0CZ53, ADDA_STRPQ ;  B2IPX3, ADDA_STRPS ;  B5XKR4, ADDA_STRPZ ;
DR   Q8DPR6, ADDA_STRR6 ;  A4W0M7, ADDA_STRS2 ;  C0MGY6, ADDA_STRS7 ;
DR   A3CNT9, ADDA_STRSV ;  A4VUD2, ADDA_STRSY ;  Q5LY80, ADDA_STRT1 ;
DR   Q5M2T7, ADDA_STRT2 ;  Q03IZ8, ADDA_STRTD ;  B9DRV0, ADDA_STRU0 ;
DR   Q67MD5, ADDA_SYMTH ;  Q0AXU8, ADDA_SYNWW ;  B0KDB7, ADDA_THEP3 ;
DR   B0K213, ADDA_THEPX ;  Q8RCZ0, ADDA_THETN ;  A6TVN9, ADDB_ALKMQ ;
DR   A8MJ51, ADDB_ALKOO ;  B7GM52, ADDB_ANOFW ;  A7Z367, ADDB_BACA2 ;
DR   A0RAX6, ADDB_BACAH ;  Q81TW2, ADDB_BACAN ;  B7JDU3, ADDB_BACC0 ;
DR   Q73C24, ADDB_BACC1 ;  B7IL83, ADDB_BACC2 ;  B7HGP8, ADDB_BACC4 ;
DR   B7HZR4, ADDB_BACC7 ;  A7GM36, ADDB_BACCN ;  B9ITE8, ADDB_BACCQ ;
DR   Q81GQ0, ADDB_BACCR ;  Q63EM3, ADDB_BACCZ ;  Q6HM44, ADDB_BACHK ;
DR   Q65LK0, ADDB_BACLD ;  A8FBR0, ADDB_BACP2 ;  P23477, ADDB_BACSU ;
DR   A9VJ01, ADDB_BACWK ;  Q3AA34, ADDB_CARHZ ;  Q97GV2, ADDB_CLOAB ;
DR   A7FR61, ADDB_CLOB1 ;  A6LPC3, ADDB_CLOB8 ;  B2UX56, ADDB_CLOBA ;
DR   B2THC7, ADDB_CLOBB ;  A5HYX0, ADDB_CLOBH ;  B1IEL7, ADDB_CLOBK ;
DR   A7GAI7, ADDB_CLOBL ;  B1KUY8, ADDB_CLOBM ;  B8I2Y3, ADDB_CLOCE ;
DR   Q18AP0, ADDB_CLOD6 ;  B9E0C6, ADDB_CLOK1 ;  A0PY66, ADDB_CLONN ;
DR   Q0TV47, ADDB_CLOP1 ;  Q8XPE3, ADDB_CLOPE ;  A9KTE7, ADDB_CLOPH ;
DR   Q0SWW7, ADDB_CLOPS ;  Q897P5, ADDB_CLOTE ;  A3DH20, ADDB_CLOTH ;
DR   B1I494, ADDB_DESAP ;  B8FXD8, ADDB_DESHD ;  Q24WW7, ADDB_DESHY ;
DR   A4J4E2, ADDB_DESRM ;  Q836J9, ADDB_ENTFA ;  B1YKM7, ADDB_EXIS2 ;
DR   Q5L264, ADDB_GEOKA ;  A4IKW6, ADDB_GEOTN ;  B0TDI1, ADDB_HELMI ;
DR   Q5FJW9, ADDB_LACAC ;  Q03NA6, ADDB_LACBA ;  Q038V6, ADDB_LACC3 ;
DR   B3WEJ2, ADDB_LACCB ;  Q1GAB0, ADDB_LACDA ;  Q04AN8, ADDB_LACDB ;
DR   B2GEY3, ADDB_LACF3 ;  Q043G5, ADDB_LACGA ;  A8YVK1, ADDB_LACH4 ;
DR   Q74JA5, ADDB_LACJO ;  Q9CJJ0, ADDB_LACLA ;  A2RH76, ADDB_LACLM ;
DR   Q033I2, ADDB_LACLS ;  Q88U40, ADDB_LACPL ;  A5VHK1, ADDB_LACRD ;
DR   B2G531, ADDB_LACRJ ;  Q1WRR9, ADDB_LACS1 ;  Q38X70, ADDB_LACSS ;
DR   B1MZM3, ADDB_LEUCK ;  Q03W48, ADDB_LEUMM ;  Q929A8, ADDB_LISIN ;
DR   Q71X98, ADDB_LISMF ;  B8DF43, ADDB_LISMH ;  Q8Y510, ADDB_LISMO ;
DR   A0AL19, ADDB_LISW6 ;  B1HN89, ADDB_LYSSC ;  Q2RL78, ADDB_MOOTA ;
DR   B2A611, ADDB_NATTJ ;  Q8ERW6, ADDB_OCEIH ;  Q04GY8, ADDB_OENOB ;
DR   Q03D70, ADDB_PEDPA ;  A5D1P4, ADDB_PELTS ;  A7X0I1, ADDB_STAA1 ;
DR   A6U073, ADDB_STAA2 ;  Q2FIA9, ADDB_STAA3 ;  Q2FZT6, ADDB_STAA8 ;
DR   A5IRE4, ADDB_STAA9 ;  Q2YWU2, ADDB_STAAB ;  Q5HHB8, ADDB_STAAC ;
DR   A6QFH7, ADDB_STAAE ;  Q99VC4, ADDB_STAAM ;  Q7A6H5, ADDB_STAAN ;
DR   Q6GIC2, ADDB_STAAR ;  Q6GAW0, ADDB_STAAS ;  A8Z072, ADDB_STAAT ;
DR   Q8NXF0, ADDB_STAAW ;  B9DIT7, ADDB_STACT ;  Q5HQJ5, ADDB_STAEQ ;
DR   Q8CPU0, ADDB_STAES ;  Q4L4Y2, ADDB_STAHJ ;  Q49WA5, ADDB_STAS1 ;
DR   Q3K1I5, ADDB_STRA1 ;  Q8E5U0, ADDB_STRA3 ;  Q8E062, ADDB_STRA5 ;
DR   B4U2H0, ADDB_STREM ;  A8AY34, ADDB_STRGC ;  Q8DT75, ADDB_STRMU ;
DR   Q9A0H4, ADDB_STRP1 ;  Q04KF9, ADDB_STRP2 ;  P0CZ54, ADDB_STRP3 ;
DR   B5E4P4, ADDB_STRP4 ;  Q5XCW7, ADDB_STRP6 ;  Q8P1J3, ADDB_STRP8 ;
DR   Q1JCJ9, ADDB_STRPB ;  Q1JMH6, ADDB_STRPC ;  Q1JHM2, ADDB_STRPD ;
DR   Q1J7E5, ADDB_STRPF ;  A2RFA9, ADDB_STRPG ;  B1IBR5, ADDB_STRPI ;
DR   B8ZQ31, ADDB_STRPJ ;  Q48UB9, ADDB_STRPM ;  Q97QQ0, ADDB_STRPN ;
DR   P0CZ55, ADDB_STRPQ ;  B2IPX4, ADDB_STRPS ;  B5XKR3, ADDB_STRPZ ;
DR   Q8DPR7, ADDB_STRR6 ;  A4W0M6, ADDB_STRS2 ;  C0MGY7, ADDB_STRS7 ;
DR   A3CNU0, ADDB_STRSV ;  A4VUD1, ADDB_STRSY ;  Q5LY79, ADDB_STRT1 ;
DR   Q5M2T6, ADDB_STRT2 ;  Q03IZ7, ADDB_STRTD ;  B9DRU9, ADDB_STRU0 ;
DR   Q67MD4, ADDB_SYMTH ;  B0KDB8, ADDB_THEP3 ;  B0K212, ADDB_THEPX ;
DR   Q8RCZ1, ADDB_THETN ;  Q9Y4B4, ARIP4_HUMAN;  Q99NG0, ARIP4_MOUSE;
DR   A4IHD2, ARIP4_XENTR;  Q9U7E0, ATRX_CAEEL ;  Q9GQN5, ATRX_DROME ;
DR   P46100, ATRX_HUMAN ;  P82798, ATRX_MACEU ;  Q61687, ATRX_MOUSE ;
DR   Q7YQM4, ATRX_PANTR ;  Q7YQM3, ATRX_PONPY ;  P70486, ATRX_RAT   ;
DR   P83946, ATRY_MACEU ;  O18017, BLM_CAEEL  ;  Q9I920, BLM_CHICK  ;
DR   Q9VGI8, BLM_DROME  ;  P54132, BLM_HUMAN  ;  O88700, BLM_MOUSE  ;
DR   Q9DEY9, BLM_XENLA  ;  Q6EVK6, BRM_ARATH  ;  P25439, BRM_DROME  ;
DR   Q3B7N1, CHD1L_BOVIN;  Q7ZU90, CHD1L_DANRE;  Q86WJ1, CHD1L_HUMAN;
DR   Q9CXF7, CHD1L_MOUSE;  A9X4T1, CHD1_BOMMO ;  B6ZLK2, CHD1_CHICK ;
DR   Q7KU24, CHD1_DROME ;  O14646, CHD1_HUMAN ;  P40201, CHD1_MOUSE ;
DR   O14647, CHD2_HUMAN ;  Q22516, CHD3_CAEEL ;  O16102, CHD3_DROME ;
DR   Q12873, CHD3_HUMAN ;  Q14839, CHD4_HUMAN ;  Q6PDQ2, CHD4_MOUSE ;
DR   Q8TDI0, CHD5_HUMAN ;  Q8TD26, CHD6_HUMAN ;  Q06A37, CHD7_CHICK ;
DR   Q9P2D1, CHD7_HUMAN ;  A2AJK6, CHD7_MOUSE ;  B0R0I6, CHD8_DANRE ;
DR   Q9HCK8, CHD8_HUMAN ;  Q09XV5, CHD8_MOUSE ;  Q9JIX5, CHD8_RAT   ;
DR   B5DE69, CHD8_XENTR ;  Q3L8U1, CHD9_HUMAN ;  Q8BYH8, CHD9_MOUSE ;
DR   O97159, CHDM_DROME ;  P39145, COMFA_BACSU;  P32270, DDA_BPT4   ;
DR   Q9XFH4, DDM1_ARATH ;  P54394, DING_BACSU ;  Q8X7X9, DING_ECO57 ;
DR   Q8FJN1, DING_ECOL6 ;  P27296, DING_ECOLI ;  P64315, DING_MYCBO ;
DR   P64314, DING_MYCTU ;  P29741, DING_PHOPR ;  Q57RD7, DING_SALCH ;
DR   Q5PG19, DING_SALPA ;  Q8ZQN7, DING_SALTY ;  Q83LU7, DING_SHIFL ;
DR   Q2FGY5, DING_STAA3 ;  Q2FYH5, DING_STAA8 ;  Q2YY51, DING_STAAB ;
DR   Q5HFW8, DING_STAAC ;  Q99U34, DING_STAAM ;  Q7A5K4, DING_STAAN ;
DR   Q6GGV4, DING_STAAR ;  Q6G9A7, DING_STAAS ;  Q8NWP2, DING_STAAW ;
DR   Q5HP88, DING_STAEQ ;  Q8CP71, DING_STAES ;  Q4L6F9, DING_STAHJ ;
DR   Q49XR1, DING_STAS1 ;  Q5ZKG3, DNA2L_CHICK;  P51530, DNA2L_HUMAN;
DR   Q6ZQJ5, DNA2L_MOUSE;  Q8QHA5, DNA2L_XENLA;  Q9URU2, DNA2_SCHPO ;
DR   P38859, DNA2_YEAST ;  P57611, DNAB_BUCAI ;  Q8K932, DNAB_BUCAP ;
DR   Q89A52, DNAB_BUCBP ;  Q8X5V3, DNAB_ECO57 ;  Q8FB22, DNAB_ECOL6 ;
DR   P0ACB0, DNAB_ECOLI ;  O78411, DNAB_GUITH ;  P45256, DNAB_HAEIN ;
DR   Q9ZJM5, DNAB_HELPJ ;  O25916, DNAB_HELPY ;  Q6ABX1, DNAB_LEIXX ;
DR   P59966, DNAB_MYCBO ;  P47340, DNAB_MYCGE ;  Q9F5P4, DNAB_MYCIT ;
DR   P46394, DNAB_MYCLE ;  P75539, DNAB_MYCPN ;  P71715, DNAB_MYCTU ;
DR   Q8YZA1, DNAB_NOSS1 ;  P49519, DNAB_ODOSI ;  Q9CNL6, DNAB_PASMU ;
DR   P51333, DNAB_PORPU ;  Q1XDF3, DNAB_PORYE ;  O30477, DNAB_RHOMR ;
DR   Q1RI04, DNAB_RICBR ;  Q92HG8, DNAB_RICCN ;  Q4UL62, DNAB_RICFE ;
DR   Q9ZD08, DNAB_RICPR ;  Q68WJ2, DNAB_RICTY ;  P0A1Q5, DNAB_SALTI ;
DR   P0A1Q4, DNAB_SALTY ;  P0ACB1, DNAB_SHIFL ;  Q55418, DNAB_SYNY3 ;
DR   O83097, DNAB_TREPA ;  P37469, DNAC_BACSU ;  Q3ZBE0, DQX1_BOVIN ;
DR   Q8TE96, DQX1_HUMAN ;  Q924H9, DQX1_MOUSE ;  A6QQR4, ERC6L_BOVIN;
DR   A2BGR3, ERC6L_DANRE;  Q2NKX8, ERC6L_HUMAN;  Q8BHK9, ERC6L_MOUSE;
DR   Q8W4M7, ERCC2_ARATH;  A6QLJ0, ERCC2_BOVIN;  Q60452, ERCC2_CRIGR;
DR   Q55G81, ERCC2_DICDI;  P18074, ERCC2_HUMAN;  O08811, ERCC2_MOUSE;
DR   Q1RMT1, ERCC3_BOVIN;  Q5ZKK7, ERCC3_CHICK;  Q7ZVV1, ERCC3_DANRE;
DR   O00835, ERCC3_DICDI;  Q02870, ERCC3_DROME;  P19447, ERCC3_HUMAN;
DR   Q60HG1, ERCC3_MACFA;  P49135, ERCC3_MOUSE;  Q5RA62, ERCC3_PONAB;
DR   Q4G005, ERCC3_RAT  ;  O13768, ERCC3_SCHPO;  Q9USU3, FBH1_SCHPO ;
DR   Q8NFZ0, FBX18_HUMAN;  Q8K2I9, FBX18_MOUSE;  Q32LC7, G3BP1_BOVIN;
DR   Q13283, G3BP1_HUMAN;  P97855, G3BP1_MOUSE;  Q5RB87, G3BP1_PONAB;
DR   Q46437, GP1D_CHLMU ;  Q46259, GP1D_CHLPS ;  B0BCM3, GP1D_CHLT2 ;
DR   P0CE16, GP1D_CHLTR ;  O94247, HCS1_SCHPO ;  P34243, HCS1_YEAST ;
DR   Q8NG08, HELB_HUMAN ;  Q6NVF4, HELB_MOUSE ;  O32215, HELD_BACSU ;
DR   P15038, HELD_ECOLI ;  Q8TDG4, HELQ_HUMAN ;  Q2VPA6, HELQ_MOUSE ;
DR   A2PYH4, HFM1_HUMAN ;  A2RUV5, HFM1_XENTR ;  P51979, HFM1_YEAST ;
DR   Q12039, HMI1_YEAST ;  Q09811, HUS2_SCHPO ;  Q8RXS6, INO80_ARATH;
DR   Q74Z27, INO80_ASHGO;  A1C9W6, INO80_ASPCL;  Q4WTV7, INO80_ASPFU;
DR   A2R9H9, INO80_ASPNC;  Q2UTQ9, INO80_ASPOR;  Q0CA78, INO80_ASPTN;
DR   Q59KI4, INO80_CANAL;  Q6FV37, INO80_CANGA;  Q1DUF9, INO80_COCIM;
DR   P0CO17, INO80_CRYNB;  P0CO16, INO80_CRYNJ;  Q6BGY8, INO80_DEBHA;
DR   Q9VDY1, INO80_DROME;  Q5BAZ5, INO80_EMENI;  Q4IL82, INO80_GIBZE;
DR   Q9ULG1, INO80_HUMAN;  Q6CNY4, INO80_KLULA;  A5E0W5, INO80_LODEL;
DR   A4R227, INO80_MAGO7;  Q6ZPV2, INO80_MOUSE;  A1CZE5, INO80_NEOFI;
DR   Q872I5, INO80_NEUCR;  Q0UG82, INO80_PHANO;  O14148, INO80_SCHPO;
DR   A7EQA8, INO80_SCLS1;  Q4PGL2, INO80_USTMA;  A7TJI3, INO80_VANPO;
DR   A6ZU34, INO80_YEAS7;  P53115, INO80_YEAST;  A4H7G5, JBP2_LEIBR ;
DR   A4HVU6, JBP2_LEIIN ;  Q4QFY1, JBP2_LEIMA ;  B6EU02, JBP2_LEITA ;
DR   Q57X81, JBP2_TRYBB ;  Q4DCH3, JBP2_TRYCR ;  Q9FQ08, KU70_ARATH ;
DR   Q2MHH4, KU70_ASPOR ;  Q2MHH3, KU70_ASPSO ;  Q2H0I3, KU70_CHAGB ;
DR   Q1DU75, KU70_COCIM ;  P0CO51, KU70_CRYNB ;  P0CO50, KU70_CRYNJ ;
DR   Q54MA9, KU70_DICDI ;  Q23976, KU70_DROME ;  Q5AVC7, KU70_EMENI ;
DR   Q6CUB4, KU70_KLULA ;  Q7SA95, KU70_NEUCR ;  Q7F1M0, KU70_ORYSJ ;
DR   Q0U5F2, KU70_PHANO ;  Q26228, KU70_RHIAP ;  O94395, KU70_SCHPO ;
DR   Q6CCK2, KU70_YARLI ;  P32807, KU70_YEAST ;  Q9FQ09, KU80_ARATH ;
DR   Q4WI96, KU80_ASPFU ;  Q2MHH2, KU80_ASPOR ;  Q2MHH1, KU80_ASPSO ;
DR   Q2H6C5, KU80_CHAGB ;  Q1E6K9, KU80_COCIM ;  Q5B4H8, KU80_EMENI ;
DR   Q7RX73, KU80_NEUCR ;  Q75IP6, KU80_ORYSJ ;  Q0U8L4, KU80_PHANO ;
DR   Q9HGM8, KU80_SCHPO ;  Q6C7B9, KU80_YARLI ;  Q04437, KU80_YEAST ;
DR   Q498J7, MC6ZA_XENLA;  Q7ZY18, MC6ZB_XENLA;  P49735, MCM2_DROME ;
DR   P49736, MCM2_HUMAN ;  P97310, MCM2_MOUSE ;  P40377, MCM2_SCHPO ;
DR   P55861, MCM2_XENLA ;  Q6DIH3, MCM2_XENTR ;  P29469, MCM2_YEAST ;
DR   Q43704, MCM31_MAIZE;  Q9SX04, MCM32_MAIZE;  Q9SX03, MCM33_MAIZE;
DR   P49739, MCM3M_XENLA;  Q7ZXZ0, MCM3Z_XENLA;  Q28BS0, MCM3Z_XENTR;
DR   Q9FL33, MCM3_ARATH ;  A4FUD9, MCM3_BOVIN ;  Q5ZMN2, MCM3_CHICK ;
DR   Q9XYU1, MCM3_DROME ;  Q24849, MCM3_ENTHI ;  P25205, MCM3_HUMAN ;
DR   P25206, MCM3_MOUSE ;  Q5R8G6, MCM3_PONAB ;  P30666, MCM3_SCHPO ;
DR   P24279, MCM3_YEAST ;  Q5XK83, MCM4A_XENLA;  P30664, MCM4B_XENLA;
DR   Q26454, MCM4_DROME ;  P33991, MCM4_HUMAN ;  P49717, MCM4_MOUSE ;
DR   P29458, MCM4_SCHPO ;  Q6GL41, MCM4_XENTR ;  P30665, MCM4_YEAST ;
DR   P55862, MCM5A_XENLA;  Q6PCI7, MCM5B_XENLA;  Q0V8B7, MCM5_BOVIN ;
DR   Q21902, MCM5_CAEEL ;  Q54CP4, MCM5_DICDI ;  Q9VGW6, MCM5_DROME ;
DR   P33992, MCM5_HUMAN ;  P49718, MCM5_MOUSE ;  P41389, MCM5_SCHPO ;
DR   Q561P5, MCM5_XENTR ;  P29496, MCM5_YEAST ;  Q5FWY4, MCM6M_XENLA;
DR   Q28CM3, MCM6M_XENTR;  Q6P1V8, MCM6Z_XENTR;  Q7Q0Q1, MCM6_ANOGA ;
DR   Q2KIZ8, MCM6_BOVIN ;  Q61J08, MCM6_CAEBR ;  P34647, MCM6_CAEEL ;
DR   Q86B14, MCM6_DICDI ;  Q9V461, MCM6_DROME ;  Q29JI9, MCM6_DROPS ;
DR   Q14566, MCM6_HUMAN ;  P97311, MCM6_MOUSE ;  Q62724, MCM6_RAT   ;
DR   P49731, MCM6_SCHPO ;  P53091, MCM6_YEAST ;  Q91876, MCM7A_XENLA;
DR   Q7ZXB1, MCM7B_XENLA;  Q3ZBH9, MCM7_BOVIN ;  Q9XYU0, MCM7_DROME ;
DR   P33993, MCM7_HUMAN ;  Q61881, MCM7_MOUSE ;  O75001, MCM7_SCHPO ;
DR   Q6NX31, MCM7_XENTR ;  P38132, MCM7_YEAST ;  Q9UXG1, MCM_SULSO  ;
DR   Q9UT23, MFH1_SCHPO ;  Q75AA7, MPH1_ASHGO ;  A1CS00, MPH1_ASPCL ;
DR   B0XMV6, MPH1_ASPFC ;  Q4WKB5, MPH1_ASPFU ;  A2Q8R2, MPH1_ASPNC ;
DR   Q2URJ5, MPH1_ASPOR ;  Q0CWI2, MPH1_ASPTN ;  A6RIS1, MPH1_BOTFB ;
DR   Q5A1A0, MPH1_CANAL ;  Q6FPQ3, MPH1_CANGA ;  Q2HG76, MPH1_CHAGB ;
DR   Q1DY43, MPH1_COCIM ;  Q6BRF0, MPH1_DEBHA ;  Q6CQX2, MPH1_KLULA ;
DR   A4RN08, MPH1_MAGO7 ;  A1D4V5, MPH1_NEOFI ;  Q7SDF3, MPH1_NEUCR ;
DR   A3GH78, MPH1_PICST ;  A7EFH4, MPH1_SCLS1 ;  A7TSV4, MPH1_VANPO ;
DR   A6ZVS0, MPH1_YEAS7 ;  P40562, MPH1_YEAST ;  Q8IVL1, NAV2_HUMAN ;
DR   O34580, PCRA_BACSU ;  P56255, PCRA_GEOSE ;  Q9S3Q0, PCRA_LEUCI ;
DR   P0A5A4, PCRA_MYCBO ;  Q9CD72, PCRA_MYCLE ;  P0A5A3, PCRA_MYCTU ;
DR   Q53727, PCRA_STAA8 ;  Q5HEL7, PCRA_STAAC ;  P64318, PCRA_STAAM ;
DR   P64319, PCRA_STAAN ;  Q6GFF2, PCRA_STAAR ;  Q6G828, PCRA_STAAS ;
DR   Q8NVT1, PCRA_STAAW ;  Q5HN29, PCRA_STAEQ ;  Q8CRT9, PCRA_STAES ;
DR   Q5ZIW1, PEO1_CHICK ;  Q96RR1, PEO1_HUMAN ;  Q8CIW5, PEO1_MOUSE ;
DR   Q7ZV90, PIF1_DANRE ;  Q9H611, PIF1_HUMAN ;  Q80SX8, PIF1_MOUSE ;
DR   Q1HG60, PIF1_RAT   ;  Q9UUA2, PIF1_SCHPO ;  Q0R4F1, PIF1_XENLA ;
DR   A6ZM04, PIF1_YEAS7 ;  P07271, PIF1_YEAST ;  P10277, PRIM_BPP4  ;
DR   P20315, PRIM_BPT3  ;  P03692, PRIM_BPT7  ;  P0C6W1, R1AB_BC133 ;
DR   P0C6V9, R1AB_BC279 ;  P0C6W0, R1AB_BC512 ;  P0C6W2, R1AB_BCHK3 ;
DR   P0C6W3, R1AB_BCHK4 ;  P0C6W4, R1AB_BCHK5 ;  P0C6W5, R1AB_BCHK9 ;
DR   P0C6W6, R1AB_BCRP3 ;  P0C6V7, R1AB_BEV   ;  P0C6V8, R1AB_BRV1  ;
DR   P0C6W7, R1AB_CVBEN ;  P0C6W8, R1AB_CVBLU ;  P0C6W9, R1AB_CVBM  ;
DR   P0C6X0, R1AB_CVBQ  ;  P0C6X1, R1AB_CVH22 ;  P0C6X2, R1AB_CVHN1 ;
DR   P0C6X3, R1AB_CVHN2 ;  P0C6X4, R1AB_CVHN5 ;  P0C6X5, R1AB_CVHNL ;
DR   P0C6X6, R1AB_CVHOC ;  P0C6X7, R1AB_CVHSA ;  P0C6X8, R1AB_CVM2  ;
DR   P0C6X9, R1AB_CVMA5 ;  P0C6Y0, R1AB_CVMJH ;  P0C6Y5, R1AB_CVPPU ;
DR   Q98VG9, R1AB_FIPV  ;  P0C6Y1, R1AB_IBVB  ;  P0C6Y2, R1AB_IBVBC ;
DR   P0C6Y3, R1AB_IBVM  ;  P0C6Y4, R1AB_PEDV7 ;  Q008X6, R1AB_WBV24 ;
DR   P26659, RAD15_SCHPO;  Q6E6J3, RAD25_ANTLO;  Q8SSK1, RAD25_ENCCU;
DR   A9CRJ7, RAD25_ENTBH;  C4V922, RAD25_NOSCE;  Q00578, RAD25_YEAST;
DR   P40352, RAD26_YEAST;  P06839, RAD3_YEAST ;  Q09772, RDH54_SCHPO;
DR   B3LN76, RDH54_YEAS1;  C7GQI8, RDH54_YEAS2;  B5VE38, RDH54_YEAS6;
DR   A6ZL17, RDH54_YEAS7;  P38086, RDH54_YEAST;  O67837, RECG_AQUAE ;
DR   O34942, RECG_BACSU ;  O51528, RECG_BORBU ;  Q8XD86, RECG_ECO57 ;
DR   P24230, RECG_ECOLI ;  P43809, RECG_HAEIN ;  Q9ZJA1, RECG_HELPJ ;
DR   O26051, RECG_HELPY ;  P64323, RECG_MYCBO ;  O69460, RECG_MYCLE ;
DR   P64322, RECG_MYCTU ;  Q9CMB4, RECG_PASMU ;  O50581, RECG_STAA8 ;
DR   Q5HGK6, RECG_STAAC ;  P64324, RECG_STAAM ;  P64325, RECG_STAAN ;
DR   Q6GHK8, RECG_STAAR ;  Q6G9Y6, RECG_STAAS ;  Q8NX11, RECG_STAAW ;
DR   Q5HPW4, RECG_STAEQ ;  Q8CSV3, RECG_STAES ;  Q54900, RECG_STRPN ;
DR   Q55681, RECG_SYNY3 ;  O50224, RECG_THIFE ;  P96130, RECG_TREPA ;
DR   A8WK63, RECQ1_CAEBR;  Q9TXJ8, RECQ1_CAEEL;  P46063, RECQ1_HUMAN;
DR   Q9Z129, RECQ1_MOUSE;  Q5RF63, RECQ1_PONAB;  Q6AYJ1, RECQ1_RAT  ;
DR   O94761, RECQ4_HUMAN;  Q75NR7, RECQ4_MOUSE;  O94762, RECQ5_HUMAN;
DR   O34748, RECQ_BACSU ;  P15043, RECQ_ECOLI ;  P71359, RECQ_HAEIN ;
DR   Q9CL21, RECQ_PASMU ;  P40724, RECQ_SALTY ;  P73421, RECQ_SYNY3 ;
DR   P50729, RECS_BACSU ;  P57654, REP_BUCAI  ;  O51889, REP_BUCAP  ;
DR   Q89A21, REP_BUCBP  ;  P09980, REP_ECOLI  ;  P44804, REP_HAEIN  ;
DR   Q9L6S1, REP_SALTY  ;  Q9YCB6, RGYR1_AERPE;  O67037, RGYR1_AQUAE;
DR   Q97ZZ8, RGYR1_SULSO;  Q971T7, RGYR1_SULTO;  Q9YC75, RGYR2_AERPE;
DR   O67226, RGYR2_AQUAE;  Q97ZF5, RGYR2_SULSO;  Q975P6, RGYR2_SULTO;
DR   O29238, RGYR_ARCFU ;  Q58907, RGYR_METJA ;  Q9UZ86, RGYR_PYRAB ;
DR   Q8ZXT5, RGYR_PYRAE ;  P95479, RGYR_PYRFU ;  O58530, RGYR_PYRHO ;
DR   Q6F598, RGYR_PYRKO ;  Q08582, RGYR_SULAC ;  P74759, RGYR_SULSH ;
DR   O51934, RGYR_THEMA ;  Q8R979, RGYR_THETN ;  P19811, RPOA_EAVBU ;
DR   Q06502, RPOA_LDVC  ;  Q83017, RPOA_LDVP  ;  Q9YN02, RPOA_PRRS1 ;
DR   Q8B912, RPOA_PRRSB ;  Q04561, RPOA_PRRSL ;  Q9WJB2, RPOA_PRRSR ;
DR   A0MD28, RPOA_PRRSS ;  Q68772, RPOA_SHFV  ;  Q9FT74, RQL1_ARATH ;
DR   Q9FT73, RQL2_ARATH ;  Q9FT72, RQL3_ARATH ;  Q8L840, RQL4A_ARATH;
DR   Q9FT70, RQL4B_ARATH;  Q0WVW7, RQL5_ARATH ;  Q9FT69, RQSIM_ARATH;
DR   Q16X92, RTEL1_AEDAE;  Q7QEI1, RTEL1_ANOGA;  A4K436, RTEL1_BOVIN;
DR   A8WS58, RTEL1_CAEBR;  Q93575, RTEL1_CAEEL;  B0W9F4, RTEL1_CULQU;
DR   P0C928, RTEL1_DANRE;  B3MSG8, RTEL1_DROAN;  B3NSW1, RTEL1_DROER;
DR   B4JNS2, RTEL1_DROGR;  Q9W484, RTEL1_DROME;  B4L1Z2, RTEL1_DROMO;
DR   B4GU19, RTEL1_DROPE;  Q29FS3, RTEL1_DROPS;  B4I0K4, RTEL1_DROSE;
DR   B4M891, RTEL1_DROVI;  B4NDG5, RTEL1_DROWI;  B4PZB4, RTEL1_DROYA;
DR   Q9NZ71, RTEL1_HUMAN;  Q0VGM9, RTEL1_MOUSE;  Q6H1L8, RTEL1_MUSSP;
DR   Q5RE34, RTEL1_PONAB;  Q5RJZ1, RTEL1_RAT  ;  B0CAE7, RUVA_ACAM1 ;
DR   A9NF61, RUVA_ACHLI ;  A1TUZ2, RUVA_ACIAC ;  Q6F992, RUVA_ACIAD ;
DR   B7GYB6, RUVA_ACIB3 ;  B7I5A8, RUVA_ACIB5 ;  B2HWT2, RUVA_ACIBC ;
DR   B0VT90, RUVA_ACIBS ;  A3M7W0, RUVA_ACIBT ;  B0VDI6, RUVA_ACIBY ;
DR   A0LUK6, RUVA_ACIC1 ;  C1F8Z2, RUVA_ACIC5 ;  A5G2L3, RUVA_ACICJ ;
DR   B9MCH5, RUVA_ACIET ;  B7J3G2, RUVA_ACIF2 ;  B5EJL8, RUVA_ACIF5 ;
DR   A1WC36, RUVA_ACISJ ;  A3MZ05, RUVA_ACTP2 ;  B3H0C5, RUVA_ACTP7 ;
DR   A6VQA4, RUVA_ACTSZ ;  A0KPA3, RUVA_AERHH ;  A4SJ25, RUVA_AERS4 ;
DR   B9J9J0, RUVA_AGRRK ;  Q8U9K5, RUVA_AGRT5 ;  B9JRI6, RUVA_AGRVS ;
DR   Q0A5Q3, RUVA_ALHEH ;  B6EGJ3, RUVA_ALISL ;  A6TQM4, RUVA_ALKMQ ;
DR   A8MHI4, RUVA_ALKOO ;  B4RTT9, RUVA_ALTMD ;  B3EU33, RUVA_AMOA5 ;
DR   B8JF04, RUVA_ANAD2 ;  Q2IPJ6, RUVA_ANADE ;  A7H906, RUVA_ANADF ;
DR   B9KHQ6, RUVA_ANAMF ;  Q5PBM0, RUVA_ANAMM ;  Q2GLG0, RUVA_ANAPZ ;
DR   B4UFY0, RUVA_ANASK ;  B9MRB2, RUVA_ANATD ;  Q3M9A3, RUVA_ANAVT ;
DR   B7GFM6, RUVA_ANOFW ;  A8EST5, RUVA_ARCB4 ;  Q5P2U6, RUVA_AROAE ;
DR   B8H9D7, RUVA_ARTCA ;  A0JXB2, RUVA_ARTS2 ;  A8IM99, RUVA_AZOC5 ;
DR   B6YR38, RUVA_AZOPC ;  A1K314, RUVA_AZOSB ;  A7Z769, RUVA_BACA2 ;
DR   C3P9A8, RUVA_BACAA ;  C3L6V0, RUVA_BACAC ;  A0RJ27, RUVA_BACAH ;
DR   Q81LG8, RUVA_BACAN ;  Q730B1, RUVA_BACC1 ;  B7IIT3, RUVA_BACC2 ;
DR   C1ESW5, RUVA_BACC3 ;  B7HE55, RUVA_BACC4 ;  B7HQI0, RUVA_BACC7 ;
DR   A7GTA3, RUVA_BACCN ;  Q817W3, RUVA_BACCR ;  Q634C3, RUVA_BACCZ ;
DR   Q5L9Q7, RUVA_BACFN ;  Q64PZ9, RUVA_BACFR ;  Q9KDI9, RUVA_BACHD ;
DR   Q6HDA5, RUVA_BACHK ;  Q65GP5, RUVA_BACLD ;  A8FFR3, RUVA_BACP2 ;
DR   Q5WHR6, RUVA_BACSK ;  O05392, RUVA_BACSU ;  Q8A6A7, RUVA_BACTN ;
DR   A6L0X5, RUVA_BACV8 ;  A9VIP7, RUVA_BACWK ;  A1UR85, RUVA_BARBK ;
DR   Q6G5R0, RUVA_BARHE ;  Q6FYP5, RUVA_BARQU ;  A9IYK7, RUVA_BART1 ;
DR   Q1LTF2, RUVA_BAUCH ;  Q6MKB7, RUVA_BDEBA ;  B2IAW4, RUVA_BEII9 ;
DR   C5C5Q7, RUVA_BEUC1 ;  B8DUE8, RUVA_BIFA0 ;  A1A1K2, RUVA_BIFAA ;
DR   B3DRX9, RUVA_BIFLD ;  Q8G6B8, RUVA_BIFLO ;  B7GR17, RUVA_BIFLS ;
DR   Q2KVY6, RUVA_BORA1 ;  Q0SPE1, RUVA_BORAP ;  Q7WGB6, RUVA_BORBR ;
DR   P70827, RUVA_BORBU ;  B7J0W2, RUVA_BORBZ ;  B5RLN1, RUVA_BORDL ;
DR   Q662Y9, RUVA_BORGA ;  B2S1L2, RUVA_BORHD ;  Q7W4T9, RUVA_BORPA ;
DR   A9I8F2, RUVA_BORPD ;  Q7VTT9, RUVA_BORPE ;  B5RQK6, RUVA_BORRA ;
DR   A1QYH6, RUVA_BORT9 ;  Q89U81, RUVA_BRAJA ;  A5ERK1, RUVA_BRASB ;
DR   A4YMC6, RUVA_BRASO ;  C0ZAN3, RUVA_BREBN ;  B2S7E0, RUVA_BRUA1 ;
DR   Q2YRD1, RUVA_BRUA2 ;  Q57BH7, RUVA_BRUAB ;  A9M7K1, RUVA_BRUC2 ;
DR   C0REW6, RUVA_BRUMB ;  P66742, RUVA_BRUME ;  A5VS59, RUVA_BRUO2 ;
DR   A9WWI0, RUVA_BRUSI ;  P66743, RUVA_BRUSU ;  B1YTE0, RUVA_BURA4 ;
DR   Q1BZ35, RUVA_BURCA ;  B1JVV4, RUVA_BURCC ;  A0K4L5, RUVA_BURCH ;
DR   B4EES6, RUVA_BURCJ ;  Q0BI82, RUVA_BURCM ;  A9AH72, RUVA_BURM1 ;
DR   A3MP73, RUVA_BURM7 ;  A2S595, RUVA_BURM9 ;  Q62HA8, RUVA_BURMA ;
DR   A1V065, RUVA_BURMS ;  A3NZ66, RUVA_BURP0 ;  Q3JNS6, RUVA_BURP1 ;
DR   A3NDF5, RUVA_BURP6 ;  B2JGU4, RUVA_BURP8 ;  B2SYK1, RUVA_BURPP ;
DR   Q63QX6, RUVA_BURPS ;  Q39JJ0, RUVA_BURS3 ;  Q2SZ54, RUVA_BURTA ;
DR   A4JBL3, RUVA_BURVG ;  Q13UC1, RUVA_BURXL ;  A4XJS2, RUVA_CALS8 ;
DR   A7ZDQ0, RUVA_CAMC1 ;  A7GYC2, RUVA_CAMC5 ;  A0RP49, RUVA_CAMFF ;
DR   A7I0X0, RUVA_CAMHC ;  A8FLL2, RUVA_CAMJ8 ;  A7H450, RUVA_CAMJD ;
DR   Q9PPC1, RUVA_CAMJE ;  A1VZE7, RUVA_CAMJJ ;  Q5HUZ3, RUVA_CAMJR ;
DR   B9KFX7, RUVA_CAMLR ;  Q3ABX9, RUVA_CARHZ ;  B8H455, RUVA_CAUCN ;
DR   Q9A3G7, RUVA_CAUCR ;  B0SUN8, RUVA_CAUSK ;  B3PB58, RUVA_CELJU ;
DR   A9WA87, RUVA_CHLAA ;  Q5L6Z3, RUVA_CHLAB ;  B8GCH4, RUVA_CHLAD ;
DR   Q3ATE5, RUVA_CHLCH ;  Q824M5, RUVA_CHLCV ;  Q252Y0, RUVA_CHLFF ;
DR   B3EFD2, RUVA_CHLL2 ;  Q9PJP0, RUVA_CHLMU ;  B3QQG1, RUVA_CHLP8 ;
DR   B3ELQ8, RUVA_CHLPB ;  A1BDH2, RUVA_CHLPD ;  Q9Z7T4, RUVA_CHLPN ;
DR   B9LCT8, RUVA_CHLSY ;  B0B875, RUVA_CHLT2 ;  B3QVA9, RUVA_CHLT3 ;
DR   Q3KLJ6, RUVA_CHLTA ;  B0BCE0, RUVA_CHLTB ;  Q8KFR0, RUVA_CHLTE ;
DR   O84509, RUVA_CHLTR ;  Q7NQB7, RUVA_CHRVO ;  A8AFI0, RUVA_CITK8 ;
DR   A5CS07, RUVA_CLAM3 ;  B0REB9, RUVA_CLAMS ;  Q97GT0, RUVA_CLOAB ;
DR   A7FY20, RUVA_CLOB1 ;  C3KTD3, RUVA_CLOB6 ;  A6LTM6, RUVA_CLOB8 ;
DR   B2V337, RUVA_CLOBA ;  B2TMZ1, RUVA_CLOBB ;  A5I6F2, RUVA_CLOBH ;
DR   C1FKG2, RUVA_CLOBJ ;  B1IMF4, RUVA_CLOBK ;  A7GHT9, RUVA_CLOBL ;
DR   B1L0B3, RUVA_CLOBM ;  B8I1A3, RUVA_CLOCE ;  Q9ZNJ6, RUVA_CLOHI ;
DR   Q0TP12, RUVA_CLOP1 ;  Q8XJ13, RUVA_CLOPE ;  A9KNV9, RUVA_CLOPH ;
DR   Q0SRN2, RUVA_CLOPS ;  Q891Z7, RUVA_CLOTE ;  A3DBU3, RUVA_CLOTH ;
DR   Q483C5, RUVA_COLP3 ;  C3PGQ7, RUVA_CORA7 ;  Q6NGX4, RUVA_CORDI ;
DR   Q8FPK4, RUVA_COREF ;  A4QEN4, RUVA_CORGB ;  Q9AE10, RUVA_CORGL ;
DR   Q4JVD8, RUVA_CORJK ;  C4LIX8, RUVA_CORK4 ;  B1VDJ7, RUVA_CORU7 ;
DR   B6J505, RUVA_COXB1 ;  B6IYU3, RUVA_COXB2 ;  A9KF41, RUVA_COXBN ;
DR   A9N9A2, RUVA_COXBR ;  Q83BE2, RUVA_COXBU ;  Q0KEC3, RUVA_CUPNH ;
DR   Q475R7, RUVA_CUPPJ ;  B2AH73, RUVA_CUPTR ;  B1WUV7, RUVA_CYAA5 ;
DR   B7K970, RUVA_CYAP7 ;  B7JZG7, RUVA_CYAP8 ;  Q11Z44, RUVA_CYTH3 ;
DR   Q478E3, RUVA_DECAR ;  Q3Z9B3, RUVA_DEHE1 ;  Q3ZZK6, RUVA_DEHSC ;
DR   Q1J0F6, RUVA_DEIGD ;  Q9RUV7, RUVA_DEIRA ;  A9BUG7, RUVA_DELAS ;
DR   B8FBT7, RUVA_DESAA ;  C6C065, RUVA_DESAD ;  C0QKP5, RUVA_DESAH ;
DR   B1I477, RUVA_DESAP ;  Q30YX6, RUVA_DESDG ;  Q24UN6, RUVA_DESHY ;
DR   C4XIJ9, RUVA_DESMR ;  A8ZUH8, RUVA_DESOH ;  A4J536, RUVA_DESRM ;
DR   Q729U3, RUVA_DESVH ;  B8DNJ8, RUVA_DESVM ;  A1VC43, RUVA_DESVV ;
DR   A5EXH7, RUVA_DICNV ;  A8LHP9, RUVA_DINSH ;  A7ZMY5, RUVA_ECO24 ;
DR   B7USN8, RUVA_ECO27 ;  B7MBS0, RUVA_ECO45 ;  B7L7R4, RUVA_ECO55 ;
DR   P0A811, RUVA_ECO57 ;  B5YR06, RUVA_ECO5E ;  B7NS57, RUVA_ECO7I ;
DR   B7MVP7, RUVA_ECO81 ;  B7M2F2, RUVA_ECO8A ;  C4ZQE5, RUVA_ECOBW ;
DR   B1XHC9, RUVA_ECODH ;  A8A161, RUVA_ECOHS ;  A1AC22, RUVA_ECOK1 ;
DR   Q0TGX1, RUVA_ECOL5 ;  P0A810, RUVA_ECOL6 ;  B1J0M7, RUVA_ECOLC ;
DR   P0A809, RUVA_ECOLI ;  B7NBL2, RUVA_ECOLU ;  B6IBU0, RUVA_ECOSE ;
DR   B1LD10, RUVA_ECOSM ;  Q1RAS3, RUVA_ECOUT ;  Q3YRE0, RUVA_EHRCJ ;
DR   Q2GHE2, RUVA_EHRCR ;  Q5FG40, RUVA_EHRRG ;  Q5HAK5, RUVA_EHRRW ;
DR   B2KCD9, RUVA_ELUMP ;  A4WBL9, RUVA_ENT38 ;  Q839T6, RUVA_ENTFA ;
DR   A7MEA2, RUVA_ENTS8 ;  Q6D4A1, RUVA_ERWCT ;  B2VJ94, RUVA_ERWT9 ;
DR   Q2N811, RUVA_ERYLH ;  B7LPI3, RUVA_ESCF3 ;  C4Z030, RUVA_EUBE2 ;
DR   B1YJR2, RUVA_EXIS2 ;  C4L522, RUVA_EXISA ;  A7HL71, RUVA_FERNB ;
DR   B0S1J4, RUVA_FINM2 ;  A6H1G0, RUVA_FLAPJ ;  A7NBV5, RUVA_FRATF ;
DR   Q2A3Q7, RUVA_FRATH ;  B2SH67, RUVA_FRATM ;  A0Q6P7, RUVA_FRATN ;
DR   Q0BM63, RUVA_FRATO ;  Q5NH17, RUVA_FRATT ;  A4IY85, RUVA_FRATW ;
DR   Q8REJ7, RUVA_FUSNN ;  C1A615, RUVA_GEMAT ;  B5EAH2, RUVA_GEOBB ;
DR   Q5KWQ9, RUVA_GEOKA ;  B3E790, RUVA_GEOLS ;  Q39XN7, RUVA_GEOMG ;
DR   B9LZC5, RUVA_GEOSF ;  Q74E87, RUVA_GEOSL ;  C6E1S9, RUVA_GEOSM ;
DR   C5D5E9, RUVA_GEOSW ;  A4IRB3, RUVA_GEOTN ;  Q7NCU2, RUVA_GLOVI ;
DR   A9HAV7, RUVA_GLUDA ;  Q5FQC5, RUVA_GLUOX ;  A0LXS4, RUVA_GRAFK ;
DR   Q7VKV4, RUVA_HAEDU ;  Q4QNM5, RUVA_HAEI8 ;  A5UAH7, RUVA_HAEIE ;
DR   A5UGC9, RUVA_HAEIG ;  P44632, RUVA_HAEIN ;  Q0I1M4, RUVA_HAES1 ;
DR   B0UVK3, RUVA_HAES2 ;  Q2SCL2, RUVA_HAHCH ;  A1WZ64, RUVA_HALHL ;
DR   B8CXG3, RUVA_HALOH ;  C4K7I5, RUVA_HAMD5 ;  Q17WH6, RUVA_HELAH ;
DR   Q7VIU0, RUVA_HELHP ;  B5Z7P2, RUVA_HELPG ;  Q1CSZ2, RUVA_HELPH ;
DR   Q9ZKW9, RUVA_HELPJ ;  B2UU34, RUVA_HELPS ;  O25549, RUVA_HELPY ;
DR   A9AZL0, RUVA_HERA2 ;  A4G1U8, RUVA_HERAR ;  Q5QYU4, RUVA_IDILO ;
DR   A6SUQ3, RUVA_JANMA ;  Q28TT0, RUVA_JANSC ;  B5XQ04, RUVA_KLEP3 ;
DR   A6TB31, RUVA_KLEP7 ;  B2GIL9, RUVA_KOCRD ;  C5CFS3, RUVA_KOSOT ;
DR   Q5FLX3, RUVA_LACAC ;  Q03R35, RUVA_LACBA ;  Q03B18, RUVA_LACC3 ;
DR   B3WC55, RUVA_LACCB ;  Q1G940, RUVA_LACDA ;  Q048Y6, RUVA_LACDB ;
DR   B2GB19, RUVA_LACF3 ;  Q045Q3, RUVA_LACGA ;  A8YTI1, RUVA_LACH4 ;
DR   Q74KV9, RUVA_LACJO ;  Q9CDL2, RUVA_LACLA ;  A2RP07, RUVA_LACLM ;
DR   Q02VS6, RUVA_LACLS ;  Q88V02, RUVA_LACPL ;  A5VIX1, RUVA_LACRD ;
DR   B2G6E7, RUVA_LACRJ ;  Q1WT17, RUVA_LACS1 ;  Q38YR0, RUVA_LACSS ;
DR   C1D5S2, RUVA_LARHH ;  Q1MP37, RUVA_LAWIP ;  Q5X5R9, RUVA_LEGPA ;
DR   A5IBE1, RUVA_LEGPC ;  Q5ZW00, RUVA_LEGPH ;  Q5WX47, RUVA_LEGPL ;
DR   Q6AFB5, RUVA_LEIXX ;  B0SGZ5, RUVA_LEPBA ;  Q04RG9, RUVA_LEPBJ ;
DR   Q053A8, RUVA_LEPBL ;  B0SQF0, RUVA_LEPBP ;  B1Y8E1, RUVA_LEPCP ;
DR   Q72T73, RUVA_LEPIC ;  B1MZV1, RUVA_LEUCK ;  Q03YJ2, RUVA_LEUMM ;
DR   Q92BI1, RUVA_LISIN ;  C1KVI0, RUVA_LISMC ;  Q71ZD7, RUVA_LISMF ;
DR   B8DHL5, RUVA_LISMH ;  Q8Y6Z7, RUVA_LISMO ;  A0AIY2, RUVA_LISW6 ;
DR   B1HVA4, RUVA_LYSSC ;  B9E719, RUVA_MACCJ ;  Q2W2A3, RUVA_MAGSA ;
DR   A0L4V9, RUVA_MAGSM ;  Q65UP1, RUVA_MANSM ;  A1U1C0, RUVA_MARAV ;
DR   Q0ALX8, RUVA_MARMM ;  A6VXD2, RUVA_MARMS ;  Q11DH5, RUVA_MESSB ;
DR   B7L255, RUVA_METC4 ;  Q609L1, RUVA_METCA ;  A9W1B3, RUVA_METEP ;
DR   Q1GYR7, RUVA_METFK ;  B8IM27, RUVA_METNO ;  B1Z924, RUVA_METPB ;
DR   A2SKV0, RUVA_METPP ;  B1M6A3, RUVA_METRJ ;  B0UA56, RUVA_METS4 ;
DR   B8EJI5, RUVA_METSB ;  B0JRV0, RUVA_MICAN ;  C5CCI2, RUVA_MICLC ;
DR   Q2RHT6, RUVA_MOOTA ;  A0QIB8, RUVA_MYCA1 ;  B3PMK3, RUVA_MYCA5 ;
DR   B1MCJ1, RUVA_MYCA9 ;  A5IY12, RUVA_MYCAP ;  P66745, RUVA_MYCBO ;
DR   A1KLU1, RUVA_MYCBP ;  C1AF62, RUVA_MYCBT ;  Q2SS60, RUVA_MYCCT ;
DR   Q7NAN2, RUVA_MYCGA ;  Q49424, RUVA_MYCGE ;  A4TBQ6, RUVA_MYCGI ;
DR   Q4A7W5, RUVA_MYCH7 ;  Q4A9R7, RUVA_MYCHJ ;  B8ZUI1, RUVA_MYCLB ;
DR   P40832, RUVA_MYCLE ;  B2HN62, RUVA_MYCMM ;  Q6MT68, RUVA_MYCMS ;
DR   Q741Q1, RUVA_MYCPA ;  Q8EWC5, RUVA_MYCPE ;  P75243, RUVA_MYCPN ;
DR   Q98PR2, RUVA_MYCPU ;  A0QWH5, RUVA_MYCS2 ;  Q4A6N7, RUVA_MYCS5 ;
DR   A3PYW4, RUVA_MYCSJ ;  A1UFA3, RUVA_MYCSK ;  Q1B9R0, RUVA_MYCSS ;
DR   A5U5U3, RUVA_MYCTA ;  P66744, RUVA_MYCTU ;  A0PPD2, RUVA_MYCUA ;
DR   A1T883, RUVA_MYCVP ;  Q1D2J5, RUVA_MYXXD ;  B2A5L5, RUVA_NATTJ ;
DR   B9L9P0, RUVA_NAUPA ;  Q5F636, RUVA_NEIG1 ;  B4RPG0, RUVA_NEIG2 ;
DR   A9M3B7, RUVA_NEIM0 ;  Q9JSM5, RUVA_NEIMA ;  Q9K1A2, RUVA_NEIMB ;
DR   A1KRU4, RUVA_NEIMF ;  Q2GDJ1, RUVA_NEOSM ;  Q0AJA4, RUVA_NITEC ;
DR   Q820S3, RUVA_NITEU ;  Q2Y5G4, RUVA_NITMU ;  Q3JES4, RUVA_NITOC ;
DR   A6Q3Z8, RUVA_NITSB ;  Q3SP13, RUVA_NITWN ;  Q5YTE7, RUVA_NOCFA ;
DR   A1SJA6, RUVA_NOCSJ ;  Q8YZT2, RUVA_NOSS1 ;  Q2GBA3, RUVA_NOVAD ;
DR   Q8EPQ5, RUVA_OCEIH ;  A6WY75, RUVA_OCHA4 ;  Q04GA2, RUVA_OENOB ;
DR   B6JIZ6, RUVA_OLICO ;  B1ZN17, RUVA_OPITP ;  A5CEJ4, RUVA_ORITB ;
DR   B3CRA9, RUVA_ORITI ;  A6LFB5, RUVA_PARD8 ;  A1AZW3, RUVA_PARDP ;
DR   A7HUZ7, RUVA_PARL1 ;  Q6MFA5, RUVA_PARUW ;  P57893, RUVA_PASMU ;
DR   C6DFF1, RUVA_PECCP ;  Q03EQ9, RUVA_PEDPA ;  Q3A231, RUVA_PELCD ;
DR   Q3B219, RUVA_PELLD ;  B4SCR7, RUVA_PELPB ;  A1ASF4, RUVA_PELPD ;
DR   A9BIJ5, RUVA_PETMO ;  B4R9Z1, RUVA_PHEZH ;  Q7N548, RUVA_PHOLL ;
DR   Q6LT49, RUVA_PHOPR ;  B3R0J1, RUVA_PHYMT ;  B1XS25, RUVA_POLNS ;
DR   Q124Q5, RUVA_POLSJ ;  A4T027, RUVA_POLSQ ;  B2RJ07, RUVA_PORG3 ;
DR   Q7MW36, RUVA_PORGI ;  B4S4U8, RUVA_PROA2 ;  Q6A8K8, RUVA_PROAC ;
DR   A3PCR4, RUVA_PROM0 ;  A2C1Y5, RUVA_PROM1 ;  A8G4N2, RUVA_PROM2 ;
DR   A9B9X1, RUVA_PROM4 ;  Q31B28, RUVA_PROM9 ;  Q7VCI6, RUVA_PROMA ;
DR   B4ETP7, RUVA_PROMH ;  Q7V7T9, RUVA_PROMM ;  Q7V1D3, RUVA_PROMP ;
DR   A2BQZ1, RUVA_PROMS ;  Q46L68, RUVA_PROMT ;  A4SGE1, RUVA_PROVI ;
DR   Q48FC4, RUVA_PSE14 ;  A6VA06, RUVA_PSEA7 ;  B7UXW6, RUVA_PSEA8 ;
DR   Q02IC8, RUVA_PSEAB ;  Q51425, RUVA_PSEAE ;  Q1I6E8, RUVA_PSEE4 ;
DR   Q4K7D8, RUVA_PSEF5 ;  C3JYS8, RUVA_PSEFS ;  Q3IIJ1, RUVA_PSEHT ;
DR   A5VZU6, RUVA_PSEP1 ;  Q3K7V9, RUVA_PSEPF ;  B0KTJ3, RUVA_PSEPG ;
DR   Q88NJ1, RUVA_PSEPK ;  B1JD71, RUVA_PSEPW ;  Q87Y34, RUVA_PSESM ;
DR   Q4ZWL2, RUVA_PSEU2 ;  A4VNA4, RUVA_PSEU5 ;  Q4FTU0, RUVA_PSYA2 ;
DR   Q1QCY6, RUVA_PSYCK ;  A1SSV5, RUVA_PSYIN ;  A5WFC8, RUVA_PSYWF ;
DR   Q1LRB6, RUVA_RALME ;  B2UFL2, RUVA_RALPJ ;  Q8Y235, RUVA_RALSO ;
DR   A9WSE5, RUVA_RENSM ;  B3PYZ4, RUVA_RHIE6 ;  Q2K4J9, RUVA_RHIEC ;
DR   Q1MC53, RUVA_RHIL3 ;  Q98F75, RUVA_RHILO ;  B5ZP79, RUVA_RHILW ;
DR   Q92M91, RUVA_RHIME ;  C3MIH6, RUVA_RHISN ;  Q7USB0, RUVA_RHOBA ;
DR   B6ITI5, RUVA_RHOCS ;  C0ZZ47, RUVA_RHOE4 ;  Q220R4, RUVA_RHOFD ;
DR   C1B4D0, RUVA_RHOOB ;  Q07H96, RUVA_RHOP5 ;  Q6NAT0, RUVA_RHOPA ;
DR   Q20X09, RUVA_RHOPB ;  Q130V1, RUVA_RHOPS ;  B3QHS2, RUVA_RHOPT ;
DR   Q2RVF6, RUVA_RHORT ;  A3PLU4, RUVA_RHOS1 ;  Q3J0F6, RUVA_RHOS4 ;
DR   A4WRW8, RUVA_RHOS5 ;  B9KKV6, RUVA_RHOSK ;  Q0S1C7, RUVA_RHOSR ;
DR   C3PNA4, RUVA_RICAE ;  A8GN94, RUVA_RICAH ;  A8GWC2, RUVA_RICB8 ;
DR   Q1RHZ6, RUVA_RICBR ;  A8EZ47, RUVA_RICCK ;  Q92I89, RUVA_RICCN ;
DR   Q4ULW8, RUVA_RICFE ;  Q9ZDE6, RUVA_RICPR ;  C4K2D5, RUVA_RICPU ;
DR   B0BXC2, RUVA_RICRO ;  A8GRW4, RUVA_RICRS ;  Q68WZ1, RUVA_RICTY ;
DR   A7NIB1, RUVA_ROSCS ;  Q168A3, RUVA_ROSDO ;  A5UZS3, RUVA_ROSS1 ;
DR   Q1AWE1, RUVA_RUBXD ;  Q21HN5, RUVA_SACD2 ;  A4FBA7, RUVA_SACEN ;
DR   B5F3J6, RUVA_SALA4 ;  A8LXW8, RUVA_SALAI ;  Q57NA2, RUVA_SALCH ;
DR   B5FSN7, RUVA_SALDC ;  B5R1V8, RUVA_SALEP ;  B5R8E2, RUVA_SALG2 ;
DR   B4T7Z3, RUVA_SALHS ;  B4SVE5, RUVA_SALNS ;  Q5PN01, RUVA_SALPA ;
DR   A9MUX3, RUVA_SALPB ;  C0Q2F4, RUVA_SALPC ;  B5BH60, RUVA_SALPK ;
DR   Q2S5C8, RUVA_SALRD ;  B4TYR8, RUVA_SALSV ;  P66747, RUVA_SALTI ;
DR   A4X5X2, RUVA_SALTO ;  P66746, RUVA_SALTY ;  A8GFI8, RUVA_SERP5 ;
DR   A1S6N9, RUVA_SHEAM ;  B8EA74, RUVA_SHEB2 ;  A3D480, RUVA_SHEB5 ;
DR   A6WNQ3, RUVA_SHEB8 ;  A9L3H8, RUVA_SHEB9 ;  Q12N09, RUVA_SHEDO ;
DR   Q081N8, RUVA_SHEFN ;  B0TSA6, RUVA_SHEHH ;  A3QEP4, RUVA_SHELP ;
DR   Q8EEF2, RUVA_SHEON ;  A8H546, RUVA_SHEPA ;  A4Y6S8, RUVA_SHEPC ;
DR   B8CNY0, RUVA_SHEPW ;  A0KWL8, RUVA_SHESA ;  A8FUW9, RUVA_SHESH ;
DR   Q0HIZ2, RUVA_SHESM ;  Q0HUZ0, RUVA_SHESR ;  A1RJQ3, RUVA_SHESW ;
DR   B1KGY0, RUVA_SHEWM ;  B2TWQ2, RUVA_SHIB3 ;  Q322E5, RUVA_SHIBS ;
DR   Q32HA0, RUVA_SHIDS ;  Q0T3U5, RUVA_SHIF8 ;  Q83KR4, RUVA_SHIFL ;
DR   Q3Z2L9, RUVA_SHISS ;  Q5LNT7, RUVA_SILPO ;  A6UCT8, RUVA_SINMW ;
DR   Q2NTI9, RUVA_SODGM ;  Q02AG7, RUVA_SOLUE ;  Q1GWB4, RUVA_SPHAL ;
DR   A5V883, RUVA_SPHWW ;  A7X358, RUVA_STAA1 ;  A6U2B0, RUVA_STAA2 ;
DR   Q2FG85, RUVA_STAA3 ;  Q2FXT3, RUVA_STAA8 ;  A5ITG6, RUVA_STAA9 ;
DR   Q2YT88, RUVA_STAAB ;  Q5HFC1, RUVA_STAAC ;  A6QHI4, RUVA_STAAE ;
DR   P66748, RUVA_STAAM ;  P66749, RUVA_STAAN ;  Q6GG62, RUVA_STAAR ;
DR   Q6G8S7, RUVA_STAAS ;  A8Z2H0, RUVA_STAAT ;  P66750, RUVA_STAAW ;
DR   B9DNE5, RUVA_STACT ;  Q5HNQ9, RUVA_STAEQ ;  Q8CS90, RUVA_STAES ;
DR   Q4L6Y7, RUVA_STAHJ ;  Q49Y80, RUVA_STAS1 ;  Q3JYM8, RUVA_STRA1 ;
DR   Q8E2R7, RUVA_STRA3 ;  Q8DWW6, RUVA_STRA5 ;  Q820F4, RUVA_STRAW ;
DR   Q9L290, RUVA_STRCO ;  C0MAS2, RUVA_STRE4 ;  B4U0J5, RUVA_STREM ;
DR   A8AZT8, RUVA_STRGC ;  B1W3G3, RUVA_STRGG ;  B4ST34, RUVA_STRM5 ;
DR   B2FRN6, RUVA_STRMK ;  Q8CWW3, RUVA_STRMU ;  P66751, RUVA_STRP1 ;
DR   Q04MQ9, RUVA_STRP2 ;  P0DF48, RUVA_STRP3 ;  B5E6D0, RUVA_STRP4 ;
DR   Q5X9H7, RUVA_STRP6 ;  C1CAI9, RUVA_STRP7 ;  Q8NZ27, RUVA_STRP8 ;
DR   Q1J9C4, RUVA_STRPB ;  Q1JJH3, RUVA_STRPC ;  Q1JEH4, RUVA_STRPD ;
DR   Q1J492, RUVA_STRPF ;  A2RGV1, RUVA_STRPG ;  B1I8F7, RUVA_STRPI ;
DR   B8ZKD4, RUVA_STRPJ ;  Q48QW4, RUVA_STRPM ;  Q97SY4, RUVA_STRPN ;
DR   P0DF49, RUVA_STRPQ ;  B2IS15, RUVA_STRPS ;  B5XJ07, RUVA_STRPZ ;
DR   Q8DRE8, RUVA_STRR6 ;  A4VYN2, RUVA_STRS2 ;  C0MGC2, RUVA_STRS7 ;
DR   A3CR11, RUVA_STRSV ;  A4VSE3, RUVA_STRSY ;  Q5M1Y4, RUVA_STRT1 ;
DR   Q5M6H5, RUVA_STRT2 ;  Q03MX8, RUVA_STRTD ;  B9DW68, RUVA_STRU0 ;
DR   C1CBY3, RUVA_STRZJ ;  C1CI73, RUVA_STRZP ;  C1CP48, RUVA_STRZT ;
DR   Q30R94, RUVA_SULDN ;  A6Q8H2, RUVA_SULNB ;  Q67Q98, RUVA_SYMTH ;
DR   Q2LRA9, RUVA_SYNAS ;  Q31KU1, RUVA_SYNE7 ;  A0LGY7, RUVA_SYNFM ;
DR   Q2JWZ2, RUVA_SYNJA ;  Q2JNW8, RUVA_SYNJB ;  B1XL12, RUVA_SYNP2 ;
DR   Q5N128, RUVA_SYNP6 ;  A5GKN1, RUVA_SYNPW ;  Q7U7F0, RUVA_SYNPX ;
DR   A5GTL6, RUVA_SYNR3 ;  Q0I9P0, RUVA_SYNS3 ;  Q3AVK0, RUVA_SYNS9 ;
DR   Q3AKG6, RUVA_SYNSC ;  Q0AX15, RUVA_SYNWW ;  P73554, RUVA_SYNY3 ;
DR   C5BQT5, RUVA_TERTT ;  B7IHQ4, RUVA_THEAB ;  Q8DLG1, RUVA_THEEB ;
DR   Q47N42, RUVA_THEFY ;  A6LLH1, RUVA_THEM4 ;  Q9WY12, RUVA_THEMA ;
DR   A5IKQ6, RUVA_THEP1 ;  B0K955, RUVA_THEP3 ;  B0K0L7, RUVA_THEPX ;
DR   B9KYT2, RUVA_THERP ;  Q72GZ9, RUVA_THET2 ;  Q9F1Q3, RUVA_THET8 ;
DR   Q8RAN3, RUVA_THETN ;  B5YKF0, RUVA_THEYD ;  Q31H84, RUVA_THICR ;
DR   Q3SGT1, RUVA_THIDA ;  B8GUJ5, RUVA_THISH ;  C4LBN1, RUVA_TOLAT ;
DR   Q73LJ9, RUVA_TREDE ;  O83554, RUVA_TREPA ;  B2S3D5, RUVA_TREPS ;
DR   Q83GK0, RUVA_TROWT ;  B1H0B1, RUVA_UNCTG ;  B1AJ90, RUVA_UREP2 ;
DR   Q9PQ41, RUVA_UREPA ;  B5ZBT6, RUVA_UREU1 ;  C5CM11, RUVA_VARPS ;
DR   A1WQ66, RUVA_VEREI ;  A5F761, RUVA_VIBC3 ;  Q9KR01, RUVA_VIBCH ;
DR   C3LNE9, RUVA_VIBCM ;  Q5E6A0, RUVA_VIBF1 ;  B5FCQ1, RUVA_VIBFM ;
DR   Q87QU8, RUVA_VIBPA ;  B7VMI3, RUVA_VIBSL ;  Q8DAN4, RUVA_VIBVU ;
DR   Q7MJ77, RUVA_VIBVY ;  Q73G51, RUVA_WOLPM ;  B3CMH6, RUVA_WOLPP ;
DR   Q7MA70, RUVA_WOLSU ;  Q5GT34, RUVA_WOLTR ;  C0R4X3, RUVA_WOLWR ;
DR   Q8PHV0, RUVA_XANAC ;  Q3BQF2, RUVA_XANC5 ;  Q4UXM0, RUVA_XANC8 ;
DR   B0RPY4, RUVA_XANCB ;  Q8P6E5, RUVA_XANCP ;  Q2P577, RUVA_XANOM ;
DR   B2STK2, RUVA_XANOP ;  Q5H2A6, RUVA_XANOR ;  A7IJV4, RUVA_XANP2 ;
DR   B2I4S9, RUVA_XYLF2 ;  Q9PC77, RUVA_XYLFA ;  B0U2E1, RUVA_XYLFM ;
DR   Q87D02, RUVA_XYLFT ;  A1JRJ9, RUVA_YERE8 ;  A7FIC6, RUVA_YERP3 ;
DR   B2K323, RUVA_YERPB ;  Q8ZEU6, RUVA_YERPE ;  A9QYX3, RUVA_YERPG ;
DR   Q66AU0, RUVA_YERPS ;  B1JLL1, RUVA_YERPY ;  Q5NR75, RUVA_ZYMMO ;
DR   Q0IFL2, RUVB1_AEDAE;  Q750R1, RUVB1_ASHGO;  Q4WPW8, RUVB1_ASPFU;
DR   Q5A0W7, RUVB1_CANAL;  Q6FU78, RUVB1_CANGA;  P0CR27, RUVB1_CRYNB;
DR   P0CR26, RUVB1_CRYNJ;  Q8AWW7, RUVB1_DANRE;  Q6BI60, RUVB1_DEBHA;
DR   Q9VH07, RUVB1_DROME;  Q29AK9, RUVB1_DROPS;  Q5BBV9, RUVB1_EMENI;
DR   Q8STP2, RUVB1_ENCCU;  Q4ICA8, RUVB1_GIBZE;  Q9Y265, RUVB1_HUMAN;
DR   Q6CQA9, RUVB1_KLULA;  P60122, RUVB1_MOUSE;  Q8WZS3, RUVB1_NEUCR;
DR   P60123, RUVB1_RAT  ;  Q9C0X6, RUVB1_SCHPO;  Q2JTM7, RUVB1_SYNJA;
DR   Q4P112, RUVB1_USTMA;  Q9DE26, RUVB1_XENLA;  Q6CB52, RUVB1_YARLI;
DR   Q03940, RUVB1_YEAST;  Q16TA2, RUVB2_AEDAE;  Q755G5, RUVB2_ASHGO;
DR   Q4WKH9, RUVB2_ASPFU;  Q2TBU9, RUVB2_BOVIN;  Q5AGZ9, RUVB2_CANAL;
DR   Q6FSF1, RUVB2_CANGA;  P0CR29, RUVB2_CRYNB;  P0CR28, RUVB2_CRYNJ;
DR   P83571, RUVB2_DANRE;  Q6BSB8, RUVB2_DEBHA;  Q54UW5, RUVB2_DICDI;
DR   Q9V3K3, RUVB2_DROME;  Q29DI0, RUVB2_DROPS;  Q5BGK3, RUVB2_EMENI;
DR   Q8SU27, RUVB2_ENCCU;  Q4I948, RUVB2_GIBZE;  Q9Y230, RUVB2_HUMAN;
DR   Q6CT29, RUVB2_KLULA;  Q9WTM5, RUVB2_MOUSE;  Q873C7, RUVB2_NEUCR;
DR   O94692, RUVB2_SCHPO;  Q2JTJ1, RUVB2_SYNJA;  Q4P6N7, RUVB2_USTMA;
DR   Q9DE27, RUVB2_XENLA;  Q6C3X6, RUVB2_YARLI;  Q12464, RUVB2_YEAST;
DR   B0C2D5, RUVB_ACAM1 ;  A9NF62, RUVB_ACHLI ;  A1TUY9, RUVB_ACIAC ;
DR   Q6F991, RUVB_ACIAD ;  B7GYB5, RUVB_ACIB3 ;  B7I5A9, RUVB_ACIB5 ;
DR   B2HWT3, RUVB_ACIBC ;  Q1IHV6, RUVB_ACIBL ;  B0VT89, RUVB_ACIBS ;
DR   A3M7W1, RUVB_ACIBT ;  B0VDI5, RUVB_ACIBY ;  A0LUK5, RUVB_ACIC1 ;
DR   A1WC30, RUVB_ACISJ ;  A3MZ06, RUVB_ACTP2 ;  A6VQA3, RUVB_ACTSZ ;
DR   A0KPA2, RUVB_AERHH ;  A4SJ26, RUVB_AERS4 ;  Q8U9K6, RUVB_AGRT5 ;
DR   B9JRX1, RUVB_AGRVS ;  B2UPI9, RUVB_AKKM8 ;  Q0VRJ7, RUVB_ALCBS ;
DR   Q0A4X0, RUVB_ALHEH ;  B6EGJ4, RUVB_ALISL ;  A6TQM5, RUVB_ALKMQ ;
DR   A8MHI3, RUVB_ALKOO ;  B4RTT8, RUVB_ALTMD ;  B3ER84, RUVB_AMOA5 ;
DR   B8JF05, RUVB_ANAD2 ;  Q2IPJ5, RUVB_ANADE ;  A7H910, RUVB_ANADF ;
DR   B9KHQ5, RUVB_ANAMF ;  Q5PBM1, RUVB_ANAMM ;  Q2GLG1, RUVB_ANAPZ ;
DR   B4UFY1, RUVB_ANASK ;  B9MRB3, RUVB_ANATD ;  Q3MEF4, RUVB_ANAVT ;
DR   A8EVP9, RUVB_ARCB4 ;  Q5P2U7, RUVB_AROAE ;  A1R724, RUVB_ARTAT ;
DR   B8H9D6, RUVB_ARTCA ;  A0JXB1, RUVB_ARTS2 ;  A8IMA7, RUVB_AZOC5 ;
DR   A1K313, RUVB_AZOSB ;  C1DRF8, RUVB_AZOVD ;  A7Z768, RUVB_BACA2 ;
DR   C3P9A7, RUVB_BACAA ;  C3L6U9, RUVB_BACAC ;  A0RJ26, RUVB_BACAH ;
DR   Q81LG9, RUVB_BACAN ;  P61528, RUVB_BACC1 ;  B7IIT2, RUVB_BACC2 ;
DR   C1ESW4, RUVB_BACC3 ;  B7HE54, RUVB_BACC4 ;  B7HQH9, RUVB_BACC7 ;
DR   A7GTA2, RUVB_BACCN ;  B9IYZ4, RUVB_BACCQ ;  Q817W4, RUVB_BACCR ;
DR   Q634C4, RUVB_BACCZ ;  Q5LIX0, RUVB_BACFN ;  Q650B4, RUVB_BACFR ;
DR   Q9KDI8, RUVB_BACHD ;  Q6HDA6, RUVB_BACHK ;  Q65GP6, RUVB_BACLD ;
DR   A8FFR2, RUVB_BACP2 ;  Q5WHR5, RUVB_BACSK ;  O32055, RUVB_BACSU ;
DR   Q8A2M0, RUVB_BACTN ;  A6KZW5, RUVB_BACV8 ;  A9VIP6, RUVB_BACWK ;
DR   A1UR84, RUVB_BARBK ;  Q6G5R1, RUVB_BARHE ;  Q6FYP6, RUVB_BARQU ;
DR   A9IYK5, RUVB_BART1 ;  Q1LTF3, RUVB_BAUCH ;  P61529, RUVB_BDEBA ;
DR   B2IBR9, RUVB_BEII9 ;  A1A1K3, RUVB_BIFAA ;  B3DRY0, RUVB_BIFLD ;
DR   Q8G6B7, RUVB_BIFLO ;  B7GR18, RUVB_BIFLS ;  Q2KVY2, RUVB_BORA1 ;
DR   Q0SPE2, RUVB_BORAP ;  Q7WGB3, RUVB_BORBR ;  P70828, RUVB_BORBU ;
DR   Q662Z0, RUVB_BORGA ;  B2S1L1, RUVB_BORHD ;  Q7W4T6, RUVB_BORPA ;
DR   Q7VTT6, RUVB_BORPE ;  C0R250, RUVB_BRAHW ;  Q89U80, RUVB_BRAJA ;
DR   A5ERJ9, RUVB_BRASB ;  A4YMC8, RUVB_BRASO ;  C0ZAN4, RUVB_BREBN ;
DR   B2S7D9, RUVB_BRUA1 ;  Q2YRD2, RUVB_BRUA2 ;  Q57BH8, RUVB_BRUAB ;
DR   A9M7K0, RUVB_BRUC2 ;  C0REW5, RUVB_BRUMB ;  Q8YIV5, RUVB_BRUME ;
DR   A5VS58, RUVB_BRUO2 ;  A9WWH9, RUVB_BRUSI ;  Q8FZ02, RUVB_BRUSU ;
DR   B1YTD9, RUVB_BURA4 ;  Q1BZ36, RUVB_BURCA ;  B1JVV3, RUVB_BURCC ;
DR   Q93LP2, RUVB_BURCE ;  A0K4L4, RUVB_BURCH ;  B4EES7, RUVB_BURCJ ;
DR   Q0BI83, RUVB_BURCM ;  A9AH73, RUVB_BURM1 ;  A3MP72, RUVB_BURM7 ;
DR   A2S594, RUVB_BURM9 ;  Q62HA9, RUVB_BURMA ;  A1V064, RUVB_BURMS ;
DR   A3NZ67, RUVB_BURP0 ;  Q3JNS5, RUVB_BURP1 ;  A3NDF6, RUVB_BURP6 ;
DR   B2SYK2, RUVB_BURPP ;  Q63QX5, RUVB_BURPS ;  Q39JJ1, RUVB_BURS3 ;
DR   Q2SZ55, RUVB_BURTA ;  A4JBL2, RUVB_BURVG ;  Q13UC0, RUVB_BURXL ;
DR   A4XJS3, RUVB_CALS8 ;  A7ZEM1, RUVB_CAMC1 ;  A7GZP9, RUVB_CAMC5 ;
DR   A0RN84, RUVB_CAMFF ;  A7I1C5, RUVB_CAMHC ;  A8FN42, RUVB_CAMJ8 ;
DR   A7H1X6, RUVB_CAMJD ;  Q9PMT7, RUVB_CAMJE ;  A1W0X9, RUVB_CAMJJ ;
DR   Q5HT48, RUVB_CAMJR ;  B9KDF4, RUVB_CAMLR ;  Q3ABY0, RUVB_CARHZ ;
DR   B8H454, RUVB_CAUCN ;  Q9A3G8, RUVB_CAUCR ;  B0SUN9, RUVB_CAUSK ;
DR   B3PB59, RUVB_CELJU ;  A9WHF8, RUVB_CHLAA ;  Q5L686, RUVB_CHLAB ;
DR   B8G5S6, RUVB_CHLAD ;  Q3APQ7, RUVB_CHLCH ;  Q823K4, RUVB_CHLCV ;
DR   Q254B4, RUVB_CHLFF ;  B3EH23, RUVB_CHLL2 ;  Q9PKZ8, RUVB_CHLMU ;
DR   B3QM27, RUVB_CHLP8 ;  A1BDZ8, RUVB_CHLPD ;  Q9Z8F3, RUVB_CHLPN ;
DR   B9LBR4, RUVB_CHLSY ;  B0B9E8, RUVB_CHLT2 ;  Q3KMY1, RUVB_CHLTA ;
DR   B0BB27, RUVB_CHLTB ;  Q8KC00, RUVB_CHLTE ;  O84044, RUVB_CHLTR ;
DR   Q1QWF8, RUVB_CHRSD ;  Q7NQC5, RUVB_CHRVO ;  A8AFI1, RUVB_CITK8 ;
DR   A5CS06, RUVB_CLAM3 ;  Q97GT1, RUVB_CLOAB ;  A7FY19, RUVB_CLOB1 ;
DR   C3KTD2, RUVB_CLOB6 ;  A6LTM7, RUVB_CLOB8 ;  B2V338, RUVB_CLOBA ;
DR   B2TMZ2, RUVB_CLOBB ;  A5I6F1, RUVB_CLOBH ;  C1FKG1, RUVB_CLOBJ ;
DR   B1IMF3, RUVB_CLOBK ;  A7GHT8, RUVB_CLOBL ;  B1L0B2, RUVB_CLOBM ;
DR   Q183N8, RUVB_CLOD6 ;  B9E5Q8, RUVB_CLOK1 ;  A5N206, RUVB_CLOK5 ;
DR   A0PZV4, RUVB_CLONN ;  Q0TP13, RUVB_CLOP1 ;  Q8XJ14, RUVB_CLOPE ;
DR   A9KP49, RUVB_CLOPH ;  Q0SRN3, RUVB_CLOPS ;  Q891Z8, RUVB_CLOTE ;
DR   A3DBU4, RUVB_CLOTH ;  Q483C4, RUVB_COLP3 ;  C3PGQ6, RUVB_CORA7 ;
DR   P61530, RUVB_CORDI ;  Q8FPK5, RUVB_COREF ;  A4QEN3, RUVB_CORGB ;
DR   Q9AE09, RUVB_CORGL ;  Q4JVD9, RUVB_CORJK ;  B6J507, RUVB_COXB1 ;
DR   B6IYU2, RUVB_COXB2 ;  A9KF39, RUVB_COXBN ;  A9N9A3, RUVB_COXBR ;
DR   Q83BE0, RUVB_COXBU ;  Q0KEC4, RUVB_CUPNH ;  Q475R8, RUVB_CUPPJ ;
DR   B2AH72, RUVB_CUPTR ;  B1WP72, RUVB_CYAA5 ;  B8HY57, RUVB_CYAP4 ;
DR   B7K9M6, RUVB_CYAP7 ;  B7K1K0, RUVB_CYAP8 ;  Q11Y53, RUVB_CYTH3 ;
DR   Q478E5, RUVB_DECAR ;  Q3Z8V1, RUVB_DEHE1 ;  A5FRK7, RUVB_DEHSB ;
DR   Q3ZWZ9, RUVB_DEHSC ;  Q1J1C7, RUVB_DEIGD ;  Q9X719, RUVB_DEIRA ;
DR   A9BUG8, RUVB_DELAS ;  C0QKP4, RUVB_DESAH ;  Q30YX7, RUVB_DESDG ;
DR   B8FQV5, RUVB_DESHD ;  Q24UN7, RUVB_DESHY ;  A8ZUH7, RUVB_DESOH ;
DR   A4J537, RUVB_DESRM ;  P61531, RUVB_DESVH ;  A1VC44, RUVB_DESVV ;
DR   A5EXH6, RUVB_DICNV ;  A7ZMY4, RUVB_ECO24 ;  B7USN7, RUVB_ECO27 ;
DR   B7MBR9, RUVB_ECO45 ;  B7L7R3, RUVB_ECO55 ;  P0A813, RUVB_ECO57 ;
DR   B5YR05, RUVB_ECO5E ;  B7NS58, RUVB_ECO7I ;  B7MVZ1, RUVB_ECO81 ;
DR   B7M2F1, RUVB_ECO8A ;  C4ZQE4, RUVB_ECOBW ;  B1XHC8, RUVB_ECODH ;
DR   A8A160, RUVB_ECOHS ;  A1AC21, RUVB_ECOK1 ;  Q0TGX2, RUVB_ECOL5 ;
DR   Q8FGR3, RUVB_ECOL6 ;  B1J0M8, RUVB_ECOLC ;  P0A812, RUVB_ECOLI ;
DR   B7NBL1, RUVB_ECOLU ;  B6IBT9, RUVB_ECOSE ;  B1LD11, RUVB_ECOSM ;
DR   Q1RAS4, RUVB_ECOUT ;  C5B9T2, RUVB_EDWI9 ;  Q3YRD9, RUVB_EHRCJ ;
DR   Q2GHE3, RUVB_EHRCR ;  Q5FG39, RUVB_EHRRG ;  Q5HAK4, RUVB_EHRRW ;
DR   A4WBL8, RUVB_ENT38 ;  Q839T5, RUVB_ENTFA ;  A7MEA3, RUVB_ENTS8 ;
DR   Q6D4A2, RUVB_ERWCT ;  B2VJ95, RUVB_ERWT9 ;  Q2N814, RUVB_ERYLH ;
DR   B7LPI4, RUVB_ESCF3 ;  B1YJR1, RUVB_EXIS2 ;  C4L523, RUVB_EXISA ;
DR   A7HJD6, RUVB_FERNB ;  A5FJE5, RUVB_FLAJ1 ;  A6H1G3, RUVB_FLAPJ ;
DR   Q0RNU6, RUVB_FRAAA ;  B0U0B6, RUVB_FRAP2 ;  Q2JD94, RUVB_FRASC ;
DR   A8KZE6, RUVB_FRASN ;  Q14HJ6, RUVB_FRAT1 ;  A7NCA9, RUVB_FRATF ;
DR   Q2A3C8, RUVB_FRATH ;  B2SGL0, RUVB_FRATM ;  A0Q6B4, RUVB_FRATN ;
DR   Q0BLU4, RUVB_FRATO ;  Q5NG44, RUVB_FRATT ;  A4IXW0, RUVB_FRATW ;
DR   Q8RE97, RUVB_FUSNN ;  C1A611, RUVB_GEMAT ;  B5EAH3, RUVB_GEOBB ;
DR   Q5KWR0, RUVB_GEOKA ;  B3E468, RUVB_GEOLS ;  Q39XN6, RUVB_GEOMG ;
DR   B9LZC4, RUVB_GEOSF ;  P61532, RUVB_GEOSL ;  C6E1S8, RUVB_GEOSM ;
DR   C5D5E8, RUVB_GEOSW ;  A4IRB2, RUVB_GEOTN ;  A5G9Y2, RUVB_GEOUR ;
DR   Q7NGP9, RUVB_GLOVI ;  Q5FQC4, RUVB_GLUOX ;  Q0BT53, RUVB_GRABC ;
DR   A0LXR1, RUVB_GRAFK ;  Q7VKV5, RUVB_HAEDU ;  Q4QNM6, RUVB_HAEI8 ;
DR   A5UAH8, RUVB_HAEIE ;  P44631, RUVB_HAEIN ;  Q0I1M3, RUVB_HAES1 ;
DR   B0UVK4, RUVB_HAES2 ;  Q2SCL3, RUVB_HAHCH ;  A1WZ65, RUVB_HALHL ;
DR   C4K7I4, RUVB_HAMD5 ;  Q17WP7, RUVB_HELAH ;  Q7VIU8, RUVB_HELHP ;
DR   B0TF70, RUVB_HELMI ;  B6JKW4, RUVB_HELP2 ;  B5ZAF5, RUVB_HELPG ;
DR   Q1CUB7, RUVB_HELPH ;  Q9ZM57, RUVB_HELPJ ;  B2USM3, RUVB_HELPS ;
DR   O25699, RUVB_HELPY ;  A4G1U9, RUVB_HERAR ;  Q0C5W2, RUVB_HYPNA ;
DR   Q5QYU5, RUVB_IDILO ;  A6SUQ4, RUVB_JANMA ;  Q28TS9, RUVB_JANSC ;
DR   B5XQ05, RUVB_KLEP3 ;  A6TB30, RUVB_KLEP7 ;  C5CIU4, RUVB_KOSOT ;
DR   Q5FLX2, RUVB_LACAC ;  Q03R36, RUVB_LACBA ;  Q03B17, RUVB_LACC3 ;
DR   B3WC56, RUVB_LACCB ;  Q1G941, RUVB_LACDA ;  Q048Y7, RUVB_LACDB ;
DR   Q045Q2, RUVB_LACGA ;  A8YTI2, RUVB_LACH4 ;  P61533, RUVB_LACJO ;
DR   Q9CDL3, RUVB_LACLA ;  A2RP06, RUVB_LACLM ;  Q02VS7, RUVB_LACLS ;
DR   Q88V03, RUVB_LACPL ;  A5VIX2, RUVB_LACRD ;  B2G6E8, RUVB_LACRJ ;
DR   Q1WT18, RUVB_LACS1 ;  Q38YQ9, RUVB_LACSS ;  C1D9W9, RUVB_LARHH ;
DR   Q1MP36, RUVB_LAWIP ;  Q5X4Y6, RUVB_LEGPA ;  A5IC73, RUVB_LEGPC ;
DR   Q5ZV64, RUVB_LEGPH ;  Q5WWK4, RUVB_LEGPL ;  Q6AFB4, RUVB_LEIXX ;
DR   Q04UI9, RUVB_LEPBJ ;  Q04YY5, RUVB_LEPBL ;  B1Y8E2, RUVB_LEPCP ;
DR   P61534, RUVB_LEPIC ;  Q8F7Y2, RUVB_LEPIN ;  Q03YJ6, RUVB_LEUMM ;
DR   Q92BI2, RUVB_LISIN ;  C1KVH9, RUVB_LISMC ;  Q71ZD8, RUVB_LISMF ;
DR   B8DHL6, RUVB_LISMH ;  Q8Y6Z8, RUVB_LISMO ;  A0AIY1, RUVB_LISW6 ;
DR   B9E718, RUVB_MACCJ ;  Q2W2A5, RUVB_MAGSA ;  A0L4V5, RUVB_MAGSM ;
DR   Q65UP0, RUVB_MANSM ;  A1U1B9, RUVB_MARAV ;  Q0ALX9, RUVB_MARMM ;
DR   A6VXD3, RUVB_MARMS ;  Q11DH7, RUVB_MESSB ;  A7I4H6, RUVB_METB6 ;
DR   Q609L0, RUVB_METCA ;  Q1GYS6, RUVB_METFK ;  Q2FPZ8, RUVB_METHJ ;
DR   A2SCK0, RUVB_METPP ;  B8EK46, RUVB_METSB ;  B0JY77, RUVB_MICAN ;
DR   Q2RHT7, RUVB_MOOTA ;  A0QIB7, RUVB_MYCA1 ;  P66754, RUVB_MYCBO ;
DR   A1KLU0, RUVB_MYCBP ;  C1AF61, RUVB_MYCBT ;  Q49425, RUVB_MYCGE ;
DR   A4TBQ5, RUVB_MYCGI ;  Q600N3, RUVB_MYCH2 ;  Q4A7W4, RUVB_MYCH7 ;
DR   Q4A9R6, RUVB_MYCHJ ;  B8ZUI2, RUVB_MYCLB ;  P40833, RUVB_MYCLE ;
DR   B2HN63, RUVB_MYCMM ;  P61535, RUVB_MYCPA ;  P75242, RUVB_MYCPN ;
DR   Q98PR1, RUVB_MYCPU ;  A0QWH6, RUVB_MYCS2 ;  Q4A6N6, RUVB_MYCS5 ;
DR   A3PYW5, RUVB_MYCSJ ;  A1UFA4, RUVB_MYCSK ;  Q1B9Q9, RUVB_MYCSS ;
DR   A5U5U2, RUVB_MYCTA ;  P66753, RUVB_MYCTU ;  A0PPD3, RUVB_MYCUA ;
DR   A1T884, RUVB_MYCVP ;  Q1D2J8, RUVB_MYXXD ;  Q5F8L2, RUVB_NEIG1 ;
DR   B4RLV8, RUVB_NEIG2 ;  A9LZC3, RUVB_NEIM0 ;  Q9JUB0, RUVB_NEIMA ;
DR   Q9JZ86, RUVB_NEIMB ;  A1KU52, RUVB_NEIMF ;  Q2GDJ0, RUVB_NEOSM ;
DR   Q0AJA3, RUVB_NITEC ;  Q82XP4, RUVB_NITEU ;  Q1QHP7, RUVB_NITHX ;
DR   Q2Y5G5, RUVB_NITMU ;  Q3JES3, RUVB_NITOC ;  A6Q1X7, RUVB_NITSB ;
DR   Q3SP14, RUVB_NITWN ;  Q5YTE8, RUVB_NOCFA ;  A1SJA7, RUVB_NOCSJ ;
DR   B2ITR9, RUVB_NOSP7 ;  Q8YT32, RUVB_NOSS1 ;  Q2GBA2, RUVB_NOVAD ;
DR   Q8EPQ6, RUVB_OCEIH ;  A6WY76, RUVB_OCHA4 ;  Q04GA1, RUVB_OENOB ;
DR   A5CEJ6, RUVB_ORITB ;  B3CRA8, RUVB_ORITI ;  A6LG11, RUVB_PARD8 ;
DR   A1AZW1, RUVB_PARDP ;  A7HUZ8, RUVB_PARL1 ;  Q6MC67, RUVB_PARUW ;
DR   P57892, RUVB_PASMU ;  C6DFF2, RUVB_PECCP ;  Q03ER0, RUVB_PEDPA ;
DR   Q3A230, RUVB_PELCD ;  Q3B2F8, RUVB_PELLD ;  B4SDZ7, RUVB_PELPB ;
DR   A1ARF8, RUVB_PELPD ;  A5D3G1, RUVB_PELTS ;  B4R9Z2, RUVB_PHEZH ;
DR   Q7N547, RUVB_PHOLL ;  Q6LT48, RUVB_PHOPR ;  B3R0J0, RUVB_PHYMT ;
DR   A1VJK5, RUVB_POLNA ;  Q124Q6, RUVB_POLSJ ;  Q7MWU9, RUVB_PORGI ;
DR   B4S5I1, RUVB_PROA2 ;  Q6A8K7, RUVB_PROAC ;  A3PFA5, RUVB_PROM0 ;
DR   A2C563, RUVB_PROM1 ;  A8G7C1, RUVB_PROM2 ;  A2C638, RUVB_PROM3 ;
DR   A2BZ00, RUVB_PROM5 ;  Q318C6, RUVB_PROM9 ;  Q7V9Q4, RUVB_PROMA ;
DR   B4ETP8, RUVB_PROMH ;  Q7V910, RUVB_PROMM ;  Q7UZP3, RUVB_PROMP ;
DR   A2BTJ7, RUVB_PROMS ;  Q46IJ6, RUVB_PROMT ;  A4SG11, RUVB_PROVI ;
DR   Q48FC5, RUVB_PSE14 ;  Q15RN6, RUVB_PSEA6 ;  A6VA05, RUVB_PSEA7 ;
DR   B7UXW5, RUVB_PSEA8 ;  Q02IC9, RUVB_PSEAB ;  Q51426, RUVB_PSEAE ;
DR   Q1I6E9, RUVB_PSEE4 ;  Q4K7D9, RUVB_PSEF5 ;  C3JYS7, RUVB_PSEFS ;
DR   Q3IIJ2, RUVB_PSEHT ;  A4XRS1, RUVB_PSEMY ;  A5VZU7, RUVB_PSEP1 ;
DR   Q3K7W0, RUVB_PSEPF ;  B0KTJ2, RUVB_PSEPG ;  Q88NJ0, RUVB_PSEPK ;
DR   B1JD70, RUVB_PSEPW ;  Q87Y35, RUVB_PSESM ;  Q4ZWL1, RUVB_PSEU2 ;
DR   A4VNA3, RUVB_PSEU5 ;  Q4FTT9, RUVB_PSYA2 ;  Q1QCY5, RUVB_PSYCK ;
DR   A1SSV6, RUVB_PSYIN ;  A5WFF6, RUVB_PSYWF ;  Q1LRB7, RUVB_RALME ;
DR   B2UFL1, RUVB_RALPJ ;  Q8Y236, RUVB_RALSO ;  B3PYZ5, RUVB_RHIE6 ;
DR   Q2K4J8, RUVB_RHIEC ;  Q1MC52, RUVB_RHIL3 ;  Q98F76, RUVB_RHILO ;
DR   B5ZP80, RUVB_RHILW ;  Q92M92, RUVB_RHIME ;  Q7UPG4, RUVB_RHOBA ;
DR   B6ITI4, RUVB_RHOCS ;  C0ZZ48, RUVB_RHOE4 ;  Q220I3, RUVB_RHOFD ;
DR   C1B4D1, RUVB_RHOOB ;  Q2IS53, RUVB_RHOP2 ;  Q07H98, RUVB_RHOP5 ;
DR   P61536, RUVB_RHOPA ;  Q20X11, RUVB_RHOPB ;  Q130V3, RUVB_RHOPS ;
DR   B3QHS4, RUVB_RHOPT ;  Q2RVF5, RUVB_RHORT ;  A3PLU2, RUVB_RHOS1 ;
DR   Q3J0F8, RUVB_RHOS4 ;  A4WRX0, RUVB_RHOS5 ;  B9KKV4, RUVB_RHOSK ;
DR   Q0S1C6, RUVB_RHOSR ;  C3PNA6, RUVB_RICAE ;  A8GN97, RUVB_RICAH ;
DR   A8GWC4, RUVB_RICB8 ;  Q1RHZ9, RUVB_RICBR ;  A8EZ44, RUVB_RICCK ;
DR   Q92I87, RUVB_RICCN ;  Q4ULW6, RUVB_RICFE ;  A8F1F7, RUVB_RICM5 ;
DR   Q9ZDE5, RUVB_RICPR ;  C4K2D4, RUVB_RICPU ;  A8GRW7, RUVB_RICRS ;
DR   Q68WZ0, RUVB_RICTY ;  A7NNH1, RUVB_ROSCS ;  Q168A2, RUVB_ROSDO ;
DR   A5UVZ9, RUVB_ROSS1 ;  Q1AWE0, RUVB_RUBXD ;  Q21HN6, RUVB_SACD2 ;
DR   A4FBA8, RUVB_SACEN ;  B5F3J7, RUVB_SALA4 ;  A8LXW9, RUVB_SALAI ;
DR   A9MND7, RUVB_SALAR ;  Q57NA3, RUVB_SALCH ;  B5FSN8, RUVB_SALDC ;
DR   B4T7Z2, RUVB_SALHS ;  B4SVE4, RUVB_SALNS ;  Q5PIA7, RUVB_SALPA ;
DR   A9MUX4, RUVB_SALPB ;  C0Q2F5, RUVB_SALPC ;  B5BH61, RUVB_SALPK ;
DR   Q2S3F9, RUVB_SALRD ;  B4TYR7, RUVB_SALSV ;  P66756, RUVB_SALTI ;
DR   A4X5X3, RUVB_SALTO ;  P66755, RUVB_SALTY ;  A8GFI7, RUVB_SERP5 ;
DR   A1S6N8, RUVB_SHEAM ;  B8EA75, RUVB_SHEB2 ;  A3D481, RUVB_SHEB5 ;
DR   A6WNQ2, RUVB_SHEB8 ;  A9L3H7, RUVB_SHEB9 ;  Q12N10, RUVB_SHEDO ;
DR   Q081N9, RUVB_SHEFN ;  B0TSA7, RUVB_SHEHH ;  A3QEP3, RUVB_SHELP ;
DR   Q8EEF3, RUVB_SHEON ;  A8H545, RUVB_SHEPA ;  A4Y6S9, RUVB_SHEPC ;
DR   B8CNY1, RUVB_SHEPW ;  A0KWL9, RUVB_SHESA ;  A8FUX0, RUVB_SHESH ;
DR   Q0HIZ1, RUVB_SHESM ;  Q0HUZ1, RUVB_SHESR ;  A1RJQ2, RUVB_SHESW ;
DR   B1KGX9, RUVB_SHEWM ;  B2TWQ1, RUVB_SHIB3 ;  Q322E6, RUVB_SHIBS ;
DR   Q32HA1, RUVB_SHIDS ;  Q0T3U6, RUVB_SHIF8 ;  Q83KR5, RUVB_SHIFL ;
DR   Q3Z2L8, RUVB_SHISS ;  Q5LNT8, RUVB_SILPO ;  Q1GE13, RUVB_SILST ;
DR   A6UCT7, RUVB_SINMW ;  Q2NTI8, RUVB_SODGM ;  Q02AG6, RUVB_SOLUE ;
DR   Q1GWB6, RUVB_SPHAL ;  A5V881, RUVB_SPHWW ;  A7X357, RUVB_STAA1 ;
DR   A6U2A9, RUVB_STAA2 ;  Q2FG86, RUVB_STAA3 ;  Q2FXT4, RUVB_STAA8 ;
DR   A5ITG5, RUVB_STAA9 ;  Q2YT89, RUVB_STAAB ;  Q5HFC2, RUVB_STAAC ;
DR   A6QHI3, RUVB_STAAE ;  P66757, RUVB_STAAM ;  P66758, RUVB_STAAN ;
DR   Q6GG63, RUVB_STAAR ;  Q6G8S8, RUVB_STAAS ;  A8Z2G9, RUVB_STAAT ;
DR   P66759, RUVB_STAAW ;  B9DNE4, RUVB_STACT ;  Q5HNR0, RUVB_STAEQ ;
DR   Q8CS91, RUVB_STAES ;  Q4L6Y6, RUVB_STAHJ ;  Q49Y79, RUVB_STAS1 ;
DR   Q3K3X8, RUVB_STRA1 ;  Q8E7U6, RUVB_STRA3 ;  Q8E2D9, RUVB_STRA5 ;
DR   Q820F3, RUVB_STRAW ;  Q9L291, RUVB_STRCO ;  C0M7R2, RUVB_STRE4 ;
DR   B4U5F8, RUVB_STREM ;  A8AUH0, RUVB_STRGC ;  B1W3G4, RUVB_STRGG ;
DR   B4ST32, RUVB_STRM5 ;  B2FRN4, RUVB_STRMK ;  Q8DWI4, RUVB_STRMU ;
DR   Q9A1Y1, RUVB_STRP1 ;  Q04MI9, RUVB_STRP2 ;  P0DF50, RUVB_STRP3 ;
DR   B5E6T3, RUVB_STRP4 ;  Q5XEE4, RUVB_STRP6 ;  C1CB34, RUVB_STRP7 ;
DR   Q8P302, RUVB_STRP8 ;  Q1JE69, RUVB_STRPB ;  Q1JP25, RUVB_STRPC ;
DR   Q1JJ71, RUVB_STRPD ;  Q1J924, RUVB_STRPF ;  A2RC05, RUVB_STRPG ;
DR   B1I8Y6, RUVB_STRPI ;  Q48VY1, RUVB_STRPM ;  Q97SR6, RUVB_STRPN ;
DR   P0DF51, RUVB_STRPQ ;  B2ISI4, RUVB_STRPS ;  B5XJ28, RUVB_STRPZ ;
DR   Q8CWU7, RUVB_STRR6 ;  A4VYM0, RUVB_STRS2 ;  C0MC84, RUVB_STRS7 ;
DR   A3CK22, RUVB_STRSV ;  A4VSD3, RUVB_STRSY ;  Q5LXQ9, RUVB_STRT1 ;
DR   Q5M2B1, RUVB_STRT2 ;  Q03IE9, RUVB_STRTD ;  B9DSU1, RUVB_STRU0 ;
DR   C1CC50, RUVB_STRZJ ;  C1CIE0, RUVB_STRZP ;  C1CPD4, RUVB_STRZT ;
DR   Q30PX6, RUVB_SULDN ;  A6QC28, RUVB_SULNB ;  Q67Q97, RUVB_SYMTH ;
DR   Q2LRA8, RUVB_SYNAS ;  Q31Q03, RUVB_SYNE7 ;  A0LGY6, RUVB_SYNFM ;
DR   Q2JP68, RUVB_SYNJB ;  B1XMA0, RUVB_SYNP2 ;  Q5N474, RUVB_SYNP6 ;
DR   A5GI46, RUVB_SYNPW ;  Q7U9W7, RUVB_SYNPX ;  A5GQ68, RUVB_SYNR3 ;
DR   Q0IDW1, RUVB_SYNS3 ;  Q3B0J1, RUVB_SYNS9 ;  Q3AND8, RUVB_SYNSC ;
DR   Q0AX16, RUVB_SYNWW ;  Q57396, RUVB_SYNY3 ;  C5BQT4, RUVB_TERTT ;
DR   Q8DGR1, RUVB_THEEB ;  Q47N43, RUVB_THEFY ;  A8F5R0, RUVB_THELT ;
DR   A6LN82, RUVB_THEM4 ;  Q56313, RUVB_THEMA ;  A5ILH0, RUVB_THEP1 ;
DR   B0K956, RUVB_THEP3 ;  B0K0L8, RUVB_THEPX ;  B9KZ09, RUVB_THERP ;
DR   B1LAU3, RUVB_THESQ ;  P61537, RUVB_THET2 ;  Q5SL87, RUVB_THET8 ;
DR   Q56214, RUVB_THETH ;  Q8RAN2, RUVB_THETN ;  B5YKE9, RUVB_THEYD ;
DR   Q31H83, RUVB_THICR ;  Q3SGT3, RUVB_THIDA ;  B8GUJ4, RUVB_THISH ;
DR   C4LBN0, RUVB_TOLAT ;  P61538, RUVB_TREDE ;  P96115, RUVB_TREPA ;
DR   Q115Z7, RUVB_TRIEI ;  Q83HN0, RUVB_TROW8 ;  Q83MZ8, RUVB_TROWT ;
DR   B1AJ89, RUVB_UREP2 ;  Q9PQ42, RUVB_UREPA ;  B5ZBT5, RUVB_UREU1 ;
DR   C5CM03, RUVB_VARPS ;  A1WQ68, RUVB_VEREI ;  A5CW96, RUVB_VESOH ;
DR   A5F760, RUVB_VIBC3 ;  Q9KR02, RUVB_VIBCH ;  C3LNE8, RUVB_VIBCM ;
DR   Q5E699, RUVB_VIBF1 ;  B5FCQ2, RUVB_VIBFM ;  A7N1I0, RUVB_VIBHB ;
DR   Q87QU7, RUVB_VIBPA ;  B7VMI4, RUVB_VIBSL ;  Q7MJ78, RUVB_VIBVY ;
DR   P61539, RUVB_WOLPM ;  B3CMH5, RUVB_WOLPP ;  Q7M879, RUVB_WOLSU ;
DR   Q5GT33, RUVB_WOLTR ;  C0R4X2, RUVB_WOLWR ;  Q8PHV2, RUVB_XANAC ;
DR   Q3BQF5, RUVB_XANC5 ;  Q4UXL7, RUVB_XANC8 ;  B0RPY7, RUVB_XANCB ;
DR   Q8P6E7, RUVB_XANCP ;  Q2P575, RUVB_XANOM ;  B2STK0, RUVB_XANOP ;
DR   Q5H2A4, RUVB_XANOR ;  B2I4T1, RUVB_XYLF2 ;  Q9PC79, RUVB_XYLFA ;
DR   B0U2E3, RUVB_XYLFM ;  Q87D00, RUVB_XYLFT ;  A1JRJ5, RUVB_YERE8 ;
DR   A7FIC5, RUVB_YERP3 ;  Q1C814, RUVB_YERPA ;  B2K324, RUVB_YERPB ;
DR   Q8ZEU5, RUVB_YERPE ;  A9QYX2, RUVB_YERPG ;  Q1CJG5, RUVB_YERPN ;
DR   A4TJK0, RUVB_YERPP ;  Q66AT9, RUVB_YERPS ;  B1JLL0, RUVB_YERPY ;
DR   Q5NR72, RUVB_ZYMMO ;  P38935, SMBP2_HUMAN;  Q60560, SMBP2_MESAU;
DR   P40694, SMBP2_MOUSE;  Q9EQN5, SMBP2_RAT  ;  Q9H4L7, SMRCD_HUMAN;
DR   Q04692, SMRCD_MOUSE;  Q10213, SRS2_SCHPO ;  P12954, SRS2_YEAST ;
DR   P32597, STH1_YEAST ;  Q759G7, SWR1_ASHGO ;  Q4WAS9, SWR1_ASPFU ;
DR   Q59U81, SWR1_CANAL ;  Q6FK48, SWR1_CANGA ;  P0CO19, SWR1_CRYNB ;
DR   P0CO18, SWR1_CRYNJ ;  Q6BKC2, SWR1_DEBHA ;  Q5ARK3, SWR1_EMENI ;
DR   Q4IAK7, SWR1_GIBZE ;  Q6CJ38, SWR1_KLULA ;  Q7S133, SWR1_NEUCR ;
DR   O13682, SWR1_SCHPO ;  Q4P328, SWR1_USTMA ;  Q6CA87, SWR1_YARLI ;
DR   Q05471, SWR1_YEAST ;  Q2T9L9, T2FB_BOVIN ;  Q54KT7, T2FB_DICDI ;
DR   P41900, T2FB_DROME ;  P13984, T2FB_HUMAN ;  Q8R0A0, T2FB_MOUSE ;
DR   Q01750, T2FB_RAT   ;  O94424, T2FB_SCHPO ;  Q03123, T2FB_XENLA ;
DR   P41896, T2FB_YEAST ;  Q5EAK4, TLH1_SCHPO ;  Q1RKN3, TLH2_SCHPO ;
DR   P14565, TRAI1_ECOLI;  P22706, TRAI2_ECOLX;  P03018, UVRD_ECOLI ;
DR   Q02322, UVRD_HAEIN ;  P64321, UVRD_MYCBO ;  P45612, UVRD_MYCCT ;
DR   P47486, UVRD_MYCGE ;  P53528, UVRD_MYCLE ;  P75437, UVRD_MYCPN ;
DR   P64320, UVRD_MYCTU ;  Q1RIP8, UVRD_RICBR ;  Q92HZ6, UVRD_RICCN ;
DR   Q4ULN5, UVRD_RICFE ;  Q9ZD95, UVRD_RICPR ;  Q68WT1, UVRD_RICTY ;
DR   Q05311, UVRD_SALTY ;  P20703, UVSW_BPT4  ;  P24307, V143_NPVAC ;
DR   Q83950, V143_NPVOP ;  P03116, VE1_BPV1   ;  P11298, VE1_BPV2   ;
DR   Q8BDD7, VE1_BPV3   ;  P08344, VE1_BPV4   ;  Q705G8, VE1_BPV5   ;
DR   Q705F4, VE1_BPV6   ;  Q89536, VE1_COPV6  ;  P03112, VE1_CRPVK  ;
DR   P51894, VE1_CRPVW  ;  P06455, VE1_FPVL   ;  P36719, VE1_HPV03  ;
DR   Q07846, VE1_HPV04  ;  P06920, VE1_HPV05  ;  Q05133, VE1_HPV07  ;
DR   P06420, VE1_HPV08  ;  Q05111, VE1_HPV09  ;  P36720, VE1_HPV10  ;
DR   P04014, VE1_HPV11  ;  Q05134, VE1_HPV12  ;  Q02261, VE1_HPV13  ;
DR   P36721, VE1_HPV14  ;  Q05135, VE1_HPV15  ;  P03114, VE1_HPV16  ;
DR   Q02512, VE1_HPV17  ;  P06789, VE1_HPV18  ;  Q02048, VE1_HPV19  ;
DR   P03111, VE1_HPV1A  ;  P50758, VE1_HPV20  ;  P50759, VE1_HPV21  ;
DR   P50760, VE1_HPV22  ;  P50761, VE1_HPV23  ;  P50762, VE1_HPV24  ;
DR   Q02049, VE1_HPV25  ;  P36722, VE1_HPV26  ;  P36723, VE1_HPV27  ;
DR   P50763, VE1_HPV28  ;  P50764, VE1_HPV29  ;  P25481, VE1_HPV2A  ;
DR   Q05112, VE1_HPV30  ;  P17382, VE1_HPV31  ;  P36724, VE1_HPV32  ;
DR   P06421, VE1_HPV33  ;  P36725, VE1_HPV34  ;  P27220, VE1_HPV35  ;
DR   P50808, VE1_HPV36  ;  Q80902, VE1_HPV37  ;  Q80909, VE1_HPV38  ;
DR   P24829, VE1_HPV39  ;  P36727, VE1_HPV40  ;  P27551, VE1_HPV41  ;
DR   P27221, VE1_HPV42  ;  Q80915, VE1_HPV44  ;  P36728, VE1_HPV45  ;
DR   P22419, VE1_HPV47  ;  Q80922, VE1_HPV48  ;  P36729, VE1_HPV49  ;
DR   P26544, VE1_HPV51  ;  P36730, VE1_HPV52  ;  Q02513, VE1_HPV53  ;
DR   Q81020, VE1_HPV54  ;  P22153, VE1_HPV57  ;  P26543, VE1_HPV58  ;
DR   Q81966, VE1_HPV59  ;  P26542, VE1_HPV5B  ;  Q80943, VE1_HPV60  ;
DR   Q80950, VE1_HPV61  ;  Q07847, VE1_HPV63  ;  Q07848, VE1_HPV65  ;
DR   Q80957, VE1_HPV66  ;  Q9JH49, VE1_HPV69  ;  Q84293, VE1_HPV6A  ;
DR   P03113, VE1_HPV6B  ;  P50765, VE1_HPV70  ;  Q81999, VE1_HPV72  ;
DR   Q82007, VE1_HPV73  ;  O40619, VE1_HPVR7  ;  Q84356, VE1_MNPVA  ;
DR   P03117, VE1_PAPVD  ;  P11328, VE1_PAPVE  ;  Q02262, VE1_PCPV1  ;
DR   P81174, VE1_PCPVC  ;  P22154, VE1_RHPV1  ;  P03006, VG12_BPP22 ;
DR   Q19546, WRN_CAEEL  ;  Q14191, WRN_HUMAN  ;  O09053, WRN_MOUSE  ;
DR   O93530, WRN_XENLA  ;  Q38861, XPB1_ARATH ;  Q9FUG4, XPB2_ARATH ;
DR   Q4JC68, XPD_SULAC  ;  Q9HM14, XPD_THEAC  ;  P75438, Y340_MYCPN ;
DR   P44680, Y387_HAEIN ;  Q58352, Y942_METJA ;  Q3E7X8, YE077_YEAST;
DR   P43538, YFG6_YEAST ;  P40434, YIR7_YEAST ;  O31626, YJCD_BACSU ;
DR   P40889, YJW5_YEAST ;  Q99208, YL066_YEAST;  Q07888, YL067_YEAST;
DR   Q03099, YMN3_YEAST ;  P76257, YOAA_ECOLI ;  Q08995, YP204_YEAST;
DR   P50831, YPVA_BACSU ;  Q5UR49, YR568_MIMIV;  P0CX20, YRF11_YEAST;
DR   P40105, YRF12_YEAST;  P0CX14, YRF13_YEAST;  O13559, YRF14_YEAST;
DR   P0CX21, YRF15_YEAST;  P53819, YRF16_YEAST;  P0CX15, YRF17_YEAST;
DR   P0CX22, YRF18_YEAST;
//
ID   3.6.4.13
DE   RNA helicase.
CA   ATP + H(2)O = ADP + phosphate.
CC   -!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA.
CC   -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3'
CC       polarity.
CC   -!- Some helicases unwind DNA as well as RNA.
CC   -!- May be identical with EC 3.6.4.12 (DNA helicase).
PR   PROSITE; PDOC00039;
PR   PROSITE; PDOC51192;
DR   P05080, 194K_TRVSY ;  P17595, ALPHA_BSMV ;  Q6J5K9, ARMI_DROME ;
DR   Q9UT24, BRR2_SCHPO ;  P32639, BRR2_YEAST ;  Q8VA41, CAPSD_AQRVA;
DR   Q8JU60, CAPSD_AQRVC;  B2BNE1, CAPSD_AQRVG;  Q10752, CDC28_SCHPO;
DR   Q95YF3, CGH1_CAEEL ;  Q750G3, CHL1_ASHGO ;  A1CJ34, CHL1_ASPCL ;
DR   Q4WWE9, CHL1_ASPFU ;  A2QY22, CHL1_ASPNC ;  Q2U587, CHL1_ASPOR ;
DR   Q5AD67, CHL1_CANAL ;  Q6FKT4, CHL1_CANGA ;  Q1E5T3, CHL1_COCIM ;
DR   Q6BZD9, CHL1_DEBHA ;  Q6CIF0, CHL1_KLULA ;  A5DUW8, CHL1_LODEL ;
DR   A1D8E4, CHL1_NEOFI ;  A7UXD4, CHL1_NEUCR ;  A5DNW6, CHL1_PICGU ;
DR   A3LN13, CHL1_PICST ;  O14147, CHL1_SCHPO ;  A7ERG1, CHL1_SCLS1 ;
DR   A7TTL0, CHL1_VANPO ;  Q6CAX3, CHL1_YARLI ;  A6ZWN8, CHL1_YEAS7 ;
DR   P22516, CHL1_YEAST ;  A0R8U6, CSHA_BACAH ;  Q81VG0, CSHA_BACAN ;
DR   Q73EU1, CSHA_BACC1 ;  Q81IT9, CSHA_BACCR ;  Q63GX5, CSHA_BACCZ ;
DR   Q6HPE6, CSHA_BACHK ;  Q65N62, CSHA_BACLD ;  P96614, CSHA_BACSU ;
DR   Q5L3G9, CSHA_GEOKA ;  P54475, CSHB_BACSU ;  A8MPP1, D11L8_HUMAN;
DR   P46942, DB10_NICSY ;  A6QUM7, DBP10_AJECN;  Q757U8, DBP10_ASHGO;
DR   A1CTZ6, DBP10_ASPCL;  Q8NJM2, DBP10_ASPFU;  A2QRY2, DBP10_ASPNC;
DR   Q2UHC1, DBP10_ASPOR;  Q0CMM8, DBP10_ASPTN;  Q5ANB2, DBP10_CANAL;
DR   Q6FNA2, DBP10_CANGA;  Q2H0R2, DBP10_CHAGB;  Q1EB38, DBP10_COCIM;
DR   P0CR07, DBP10_CRYNB;  P0CR06, DBP10_CRYNJ;  Q6BL34, DBP10_DEBHA;
DR   Q5BFU7, DBP10_EMENI;  Q4HZ42, DBP10_GIBZE;  Q6CIR0, DBP10_KLULA;
DR   A5DZT7, DBP10_LODEL;  A4R5B8, DBP10_MAGO7;  A1DNG2, DBP10_NEOFI;
DR   Q7S9J4, DBP10_NEUCR;  Q0UMB6, DBP10_PHANO;  A5DLR3, DBP10_PICGU;
DR   A3LZT3, DBP10_PICST;  Q09719, DBP10_SCHPO;  A7ESL7, DBP10_SCLS1;
DR   Q4P3W3, DBP10_USTMA;  A7TGW7, DBP10_VANPO;  Q6C7X8, DBP10_YARLI;
DR   A6ZXU0, DBP10_YEAS7;  Q12389, DBP10_YEAST;  Q6FP38, DBP1_CANGA ;
DR   A6ZWD3, DBP1_YEAS7 ;  P24784, DBP1_YEAST ;  A6RGE3, DBP2_AJECN ;
DR   Q755N4, DBP2_ASHGO ;  A1C6C4, DBP2_ASPCL ;  Q4X195, DBP2_ASPFU ;
DR   A2QC74, DBP2_ASPNC ;  Q2U070, DBP2_ASPOR ;  A6SFW7, DBP2_BOTFB ;
DR   Q59LU0, DBP2_CANAL ;  Q6FLF3, DBP2_CANGA ;  Q2H720, DBP2_CHAGB ;
DR   Q1DP69, DBP2_COCIM ;  P0CQ77, DBP2_CRYNB ;  P0CQ76, DBP2_CRYNJ ;
DR   Q6BY27, DBP2_DEBHA ;  Q5B0J9, DBP2_EMENI ;  Q8SRB2, DBP2_ENCCU ;
DR   Q4IF76, DBP2_GIBZE ;  Q6CIV2, DBP2_KLULA ;  A5DS77, DBP2_LODEL ;
DR   A4QSS5, DBP2_MAGO7 ;  A1DGZ7, DBP2_NEOFI ;  Q7SBC6, DBP2_NEUCR ;
DR   A5DL80, DBP2_PICGU ;  A3LQW7, DBP2_PICST ;  P24782, DBP2_SCHPO ;
DR   A7E449, DBP2_SCLS1 ;  Q4PHU9, DBP2_USTMA ;  A7TTT5, DBP2_VANPO ;
DR   Q6C4D4, DBP2_YARLI ;  A6ZRX0, DBP2_YEAS7 ;  P24783, DBP2_YEAST ;
DR   A6QXC1, DBP3_AJECN ;  Q755A5, DBP3_ASHGO ;  A1C5V3, DBP3_ASPCL ;
DR   Q4WH83, DBP3_ASPFU ;  A2QFL3, DBP3_ASPNC ;  Q2UMH8, DBP3_ASPOR ;
DR   Q0CL13, DBP3_ASPTN ;  A6SCT6, DBP3_BOTFB ;  Q5APT8, DBP3_CANAL ;
DR   Q6FS54, DBP3_CANGA ;  Q2GUI4, DBP3_CHAGB ;  Q1DZK8, DBP3_COCIM ;
DR   P0CQ79, DBP3_CRYNB ;  P0CQ78, DBP3_CRYNJ ;  Q6BZ77, DBP3_DEBHA ;
DR   Q5AWA6, DBP3_EMENI ;  Q4IJH1, DBP3_GIBZE ;  Q6CT46, DBP3_KLULA ;
DR   A5E1W4, DBP3_LODEL ;  A1DG51, DBP3_NEOFI ;  Q7S5R1, DBP3_NEUCR ;
DR   Q0UY62, DBP3_PHANO ;  A5DAC8, DBP3_PICGU ;  A3LRW2, DBP3_PICST ;
DR   Q10202, DBP3_SCHPO ;  A7EYW0, DBP3_SCLS1 ;  Q4PDT1, DBP3_USTMA ;
DR   A7TJ36, DBP3_VANPO ;  Q6C9P3, DBP3_YARLI ;  A6ZUA1, DBP3_YEAS7 ;
DR   P20447, DBP3_YEAST ;  Q75C76, DBP4_ASHGO ;  A1CTZ2, DBP4_ASPCL ;
DR   Q4WM60, DBP4_ASPFU ;  A2QS00, DBP4_ASPNC ;  Q2UHB7, DBP4_ASPOR ;
DR   Q0CMM5, DBP4_ASPTN ;  Q5AF95, DBP4_CANAL ;  Q6FPT7, DBP4_CANGA ;
DR   Q2H2J1, DBP4_CHAGB ;  Q1EB31, DBP4_COCIM ;  P0CQ83, DBP4_CRYNB ;
DR   P0CQ82, DBP4_CRYNJ ;  Q6BXG0, DBP4_DEBHA ;  Q5BFU1, DBP4_EMENI ;
DR   Q8SR01, DBP4_ENCCU ;  Q4IAS1, DBP4_GIBZE ;  Q6CRF4, DBP4_KLULA ;
DR   A5E3K3, DBP4_LODEL ;  A4RGU2, DBP4_MAGO7 ;  A1DNF9, DBP4_NEOFI ;
DR   Q7RZ35, DBP4_NEUCR ;  Q0UMB9, DBP4_PHANO ;  A5DLF4, DBP4_PICGU ;
DR   A3GGE9, DBP4_PICST ;  Q9UTP9, DBP4_SCHPO ;  A7ESL8, DBP4_SCLS1 ;
DR   Q4P5U4, DBP4_USTMA ;  A7TJ71, DBP4_VANPO ;  Q6CGD1, DBP4_YARLI ;
DR   A6ZPU3, DBP4_YEAS7 ;  P20448, DBP4_YEAST ;  A6RC50, DBP5_AJECN ;
DR   Q75C39, DBP5_ASHGO ;  A1CFV3, DBP5_ASPCL ;  Q4WIN6, DBP5_ASPFU ;
DR   A2QUY7, DBP5_ASPNC ;  Q2U8K6, DBP5_ASPOR ;  Q0CDT1, DBP5_ASPTN ;
DR   A6SBT4, DBP5_BOTFB ;  Q5AJD0, DBP5_CANAL ;  Q6FKN8, DBP5_CANGA ;
DR   Q2HGF7, DBP5_CHAGB ;  Q1EB85, DBP5_COCIM ;  P0CQ87, DBP5_CRYNB ;
DR   P0CQ86, DBP5_CRYNJ ;  Q6BRE4, DBP5_DEBHA ;  Q5AVM1, DBP5_EMENI ;
DR   Q4HY71, DBP5_GIBZE ;  Q6CJU1, DBP5_KLULA ;  A5DZX2, DBP5_LODEL ;
DR   A4RIF1, DBP5_MAGO7 ;  A1CYG5, DBP5_NEOFI ;  Q8X0X2, DBP5_NEUCR ;
DR   Q0UCB9, DBP5_PHANO ;  A5DBI5, DBP5_PICGU ;  A3GH91, DBP5_PICST ;
DR   Q09747, DBP5_SCHPO ;  A7EY76, DBP5_SCLS1 ;  Q4P7Z8, DBP5_USTMA ;
DR   Q6C3X7, DBP5_YARLI ;  A6ZNQ1, DBP5_YEAS7 ;  P20449, DBP5_YEAST ;
DR   Q751D1, DBP6_ASHGO ;  A2QA23, DBP6_ASPNC ;  Q59MW2, DBP6_CANAL ;
DR   Q6FST5, DBP6_CANGA ;  Q6BPT8, DBP6_DEBHA ;  Q6CKZ4, DBP6_KLULA ;
DR   A5E726, DBP6_LODEL ;  A5DK47, DBP6_PICGU ;  A3LSJ2, DBP6_PICST ;
DR   Q76PD3, DBP6_SCHPO ;  A7TFZ9, DBP6_VANPO ;  Q6CDN5, DBP6_YARLI ;
DR   A6ZSB3, DBP6_YEAS7 ;  P53734, DBP6_YEAST ;  Q754J2, DBP7_ASHGO ;
DR   A1CB55, DBP7_ASPCL ;  Q4WV71, DBP7_ASPFU ;  A2RA55, DBP7_ASPNC ;
DR   Q2UE66, DBP7_ASPOR ;  Q0CF43, DBP7_ASPTN ;  A6RSH5, DBP7_BOTFB ;
DR   Q59S50, DBP7_CANAL ;  Q8TFL3, DBP7_CANGA ;  Q2GZU7, DBP7_CHAGB ;
DR   Q1E9T9, DBP7_COCIM ;  P0CQ95, DBP7_CRYNB ;  P0CQ94, DBP7_CRYNJ ;
DR   Q6BKH3, DBP7_DEBHA ;  Q5BGX6, DBP7_EMENI ;  Q4HZ68, DBP7_GIBZE ;
DR   Q6CK32, DBP7_KLULA ;  A4QX49, DBP7_MAGO7 ;  A1DE84, DBP7_NEOFI ;
DR   Q7S873, DBP7_NEUCR ;  Q0UHM7, DBP7_PHANO ;  A5DAR2, DBP7_PICGU ;
DR   A3LWH3, DBP7_PICST ;  O60173, DBP7_SCHPO ;  A7F8V8, DBP7_SCLS1 ;
DR   Q4P0Y5, DBP7_USTMA ;  A7TNT1, DBP7_VANPO ;  Q6C835, DBP7_YARLI ;
DR   A6ZZY8, DBP7_YEAS7 ;  P36120, DBP7_YEAST ;  Q756G5, DBP8_ASHGO ;
DR   A1CKJ0, DBP8_ASPCL ;  Q4WXW1, DBP8_ASPFU ;  A5AA68, DBP8_ASPNC ;
DR   Q2UKX3, DBP8_ASPOR ;  Q0CNX1, DBP8_ASPTN ;  A6SFV4, DBP8_BOTFB ;
DR   Q59PR3, DBP8_CANAL ;  Q6FQZ0, DBP8_CANGA ;  Q1E0Z3, DBP8_COCIM ;
DR   P0CR03, DBP8_CRYNB ;  P0CR02, DBP8_CRYNJ ;  Q6BGU8, DBP8_DEBHA ;
DR   Q5B3H7, DBP8_EMENI ;  Q4I662, DBP8_GIBZE ;  Q6CXW0, DBP8_KLULA ;
DR   A5E0U9, DBP8_LODEL ;  A4R8G3, DBP8_MAGO7 ;  A1D6X9, DBP8_NEOFI ;
DR   Q7RYZ7, DBP8_NEUCR ;  Q0U8V9, DBP8_PHANO ;  A5DLE0, DBP8_PICGU ;
DR   A3LP87, DBP8_PICST ;  Q9HGM5, DBP8_SCHPO ;  A7E436, DBP8_SCLS1 ;
DR   Q4PEX7, DBP8_USTMA ;  A7TK63, DBP8_VANPO ;  Q6C799, DBP8_YARLI ;
DR   A6ZT77, DBP8_YEAS7 ;  P38719, DBP8_YEAST ;  A6R2L6, DBP9_AJECN ;
DR   Q74ZC1, DBP9_ASHGO ;  A1C7F7, DBP9_ASPCL ;  Q4X0C2, DBP9_ASPFU ;
DR   A2QCW6, DBP9_ASPNC ;  Q2UFL0, DBP9_ASPOR ;  Q0CY48, DBP9_ASPTN ;
DR   A6SNX1, DBP9_BOTFB ;  Q5A4P9, DBP9_CANAL ;  Q6FUA6, DBP9_CANGA ;
DR   Q1DWF4, DBP9_COCIM ;  P0CR11, DBP9_CRYNB ;  P0CR10, DBP9_CRYNJ ;
DR   Q6BLM5, DBP9_DEBHA ;  Q5AZA6, DBP9_EMENI ;  Q4IJ56, DBP9_GIBZE ;
DR   Q6CUI6, DBP9_KLULA ;  A5E572, DBP9_LODEL ;  A4QTR1, DBP9_MAGO7 ;
DR   A1DHV3, DBP9_NEOFI ;  Q7S6F3, DBP9_NEUCR ;  Q0UZ59, DBP9_PHANO ;
DR   A5DC85, DBP9_PICGU ;  A3LV40, DBP9_PICST ;  O60080, DBP9_SCHPO ;
DR   A7EM78, DBP9_SCLS1 ;  Q4P7M1, DBP9_USTMA ;  A7TPC9, DBP9_VANPO ;
DR   Q6BZR4, DBP9_YARLI ;  A7A1G0, DBP9_YEAS7 ;  Q06218, DBP9_YEAST ;
DR   P42305, DBPA_BACSU ;  P21693, DBPA_ECOLI ;  Q3ZBV2, DD19A_BOVIN;
DR   Q9NUU7, DD19A_HUMAN;  Q61655, DD19A_MOUSE;  Q9UMR2, DD19B_HUMAN;
DR   Q5ZJF6, DDX10_CHICK;  Q54Q94, DDX10_DICDI;  Q13206, DDX10_HUMAN;
DR   Q80Y44, DDX10_MOUSE;  Q96FC9, DDX11_HUMAN;  Q6AXC6, DDX11_MOUSE;
DR   Q92771, DDX12_HUMAN;  Q54CE0, DDX17_DICDI;  P19109, DDX17_DROME;
DR   Q92841, DDX17_HUMAN;  Q501J6, DDX17_MOUSE;  Q26696, DDX17_TRYBB;
DR   Q54S03, DDX18_DICDI;  Q9VD51, DDX18_DROME;  Q9NVP1, DDX18_HUMAN;
DR   Q8K363, DDX18_MOUSE;  Q54TF8, DDX19_DICDI;  O61305, DDX19_DROME;
DR   Q0IIK5, DDX1_BOVIN ;  Q90WU3, DDX1_CHICK ;  Q55CP6, DDX1_DICDI ;
DR   Q9VNV3, DDX1_DROME ;  Q24731, DDX1_DROVI ;  Q92499, DDX1_HUMAN ;
DR   Q4R7L5, DDX1_MACFA ;  Q91VR5, DDX1_MOUSE ;  Q5NVJ8, DDX1_PONAB ;
DR   Q641Y8, DDX1_RAT   ;  A2VD92, DDX1_XENLA ;  Q5XH91, DDX1_XENTR ;
DR   P0C218, DDX20_DANRE;  Q54ZI9, DDX20_DICDI;  Q9UHI6, DDX20_HUMAN;
DR   Q9JJY4, DDX20_MOUSE;  Q9NR30, DDX21_HUMAN;  Q9JIK5, DDX21_MOUSE;
DR   Q3B8Q1, DDX21_RAT  ;  Q54Y81, DDX23_DICDI;  Q9BUQ8, DDX23_HUMAN;
DR   Q5RC67, DDX23_PONAB;  Q54TD7, DDX24_DICDI;  Q9GZR7, DDX24_HUMAN;
DR   Q9ESV0, DDX24_MOUSE;  Q5RDL2, DDX24_PONAB;  Q2TBP1, DDX25_BOVIN;
DR   Q9UHL0, DDX25_HUMAN;  Q9QY15, DDX25_MOUSE;  Q9QY16, DDX25_RAT  ;
DR   Q9DGP9, DDX25_XENLA;  A1A4H6, DDX27_BOVIN;  Q54TJ4, DDX27_DICDI;
DR   Q96GQ7, DDX27_HUMAN;  Q921N6, DDX27_MOUSE;  Q9NUL7, DDX28_HUMAN;
DR   Q4R4T6, DDX28_MACFA;  Q9CWT6, DDX28_MOUSE;  Q869P0, DDX31_DICDI;
DR   Q9H8H2, DDX31_HUMAN;  P16381, DDX3L_MOUSE;  O00571, DDX3X_HUMAN;
DR   Q62167, DDX3X_MOUSE;  O15523, DDX3Y_HUMAN;  Q62095, DDX3Y_MOUSE;
DR   Q6GVM6, DDX3Y_PANTR;  Q5RF43, DDX3Y_PONAB;  Q54QS3, DDX3_DICDI ;
DR   Q9VHP0, DDX3_DROME ;  P24346, DDX3_XENLA ;  Q54KG1, DDX41_DICDI;
DR   Q9V3C0, DDX41_DROME;  Q9UJV9, DDX41_HUMAN;  Q91VN6, DDX41_MOUSE;
DR   Q5F485, DDX42_CHICK;  Q54IV3, DDX42_DICDI;  Q86XP3, DDX42_HUMAN;
DR   Q810A7, DDX42_MOUSE;  Q5R7D1, DDX42_PONAB;  Q7ZY47, DDX42_XENLA;
DR   Q9NXZ2, DDX43_HUMAN;  Q4TVV3, DDX46_DANRE;  Q553B1, DDX46_DICDI;
DR   Q7L014, DDX46_HUMAN;  Q569Z5, DDX46_MOUSE;  Q5R6D8, DDX46_PONAB;
DR   Q62780, DDX46_RAT  ;  Q29S22, DDX47_BOVIN;  P34580, DDX47_CAEEL;
DR   Q54VT4, DDX47_DICDI;  Q9H0S4, DDX47_HUMAN;  Q9CWX9, DDX47_MOUSE;
DR   Q55BR9, DDX49_DICDI;  Q07886, DDX49_DROME;  Q9Y6V7, DDX49_HUMAN;
DR   Q4FZF3, DDX49_MOUSE;  Q5W5U4, DDX4_BOVIN ;  Q9NQI0, DDX4_HUMAN ;
DR   Q4R5S7, DDX4_MACFA ;  Q61496, DDX4_MOUSE ;  Q6GWX0, DDX4_PIG   ;
DR   Q3MSQ8, DDX4_RANLE ;  Q64060, DDX4_RAT   ;  Q91372, DDX4_XENLA ;
DR   Q9BQ39, DDX50_HUMAN;  Q99MJ9, DDX50_MOUSE;  Q6DRI7, DDX51_DANRE;
DR   Q54BD6, DDX51_DICDI;  P26802, DDX51_DROME;  Q8N8A6, DDX51_HUMAN;
DR   Q6P9R1, DDX51_MOUSE;  A5D7C1, DDX52_BOVIN;  Q86IZ9, DDX52_DICDI;
DR   Q9Y2R4, DDX52_HUMAN;  Q8K301, DDX52_MOUSE;  Q99PT0, DDX52_RAT  ;
DR   Q86TM3, DDX53_HUMAN;  Q54CD8, DDX54_DICDI;  Q8TDD1, DDX54_HUMAN;
DR   Q8K4L0, DDX54_MOUSE;  Q2NL08, DDX55_BOVIN;  Q61R02, DDX55_CAEBR;
DR   P34640, DDX55_CAEEL;  Q5ZLN8, DDX55_CHICK;  Q8JHJ2, DDX55_DANRE;
DR   Q54EC2, DDX55_DICDI;  Q9VHU1, DDX55_DROME;  Q8NHQ9, DDX55_HUMAN;
DR   Q6ZPL9, DDX55_MOUSE;  Q6AZV7, DDX55_XENLA;  Q3SZ40, DDX56_BOVIN;
DR   Q54VF1, DDX56_DICDI;  Q9NY93, DDX56_HUMAN;  Q9D0R4, DDX56_MOUSE;
DR   O95786, DDX58_HUMAN;  Q6Q899, DDX58_MOUSE;  Q9GLV6, DDX58_PIG  ;
DR   Q5T1V6, DDX59_HUMAN;  Q9DBN9, DDX59_MOUSE;  Q66HG7, DDX59_RAT  ;
DR   Q54CD6, DDX5_DICDI ;  P17844, DDX5_HUMAN ;  Q4R6M5, DDX5_MACFA ;
DR   Q61656, DDX5_MOUSE ;  A5A6J2, DDX5_PANTR ;  Q5R4I9, DDX5_PONAB ;
DR   Q8IY21, DDX60_HUMAN;  Q5H9U9, DDX6L_HUMAN;  Q9WTM2, DDX6_CAVPO ;
DR   Q5ZKB9, DDX6_CHICK ;  Q54E49, DDX6_DICDI ;  P23128, DDX6_DROME ;
DR   P26196, DDX6_HUMAN ;  P54823, DDX6_MOUSE ;  Q5RFQ5, DDX6_PONAB ;
DR   P54824, DDX6_XENLA ;  Q0IHV9, DDX6_XENTR ;  P57453, DEAD_BUCAI ;
DR   Q8K9H6, DEAD_BUCAP ;  Q89AF9, DEAD_BUCBP ;  Q8XA87, DEAD_ECO57 ;
DR   P0A9P7, DEAD_ECOL6 ;  P0A9P6, DEAD_ECOLI ;  P44586, DEAD_HAEIN ;
DR   P33906, DEAD_KLEPN ;  Q11039, DEAD_MYCTU ;  P0A9P8, DEAD_SHIFL ;
DR   A6R3L3, DED1_AJECN ;  Q75B50, DED1_ASHGO ;  A1CH78, DED1_ASPCL ;
DR   Q4WP13, DED1_ASPFU ;  A2QI25, DED1_ASPNC ;  Q2UGK3, DED1_ASPOR ;
DR   Q0CLJ6, DED1_ASPTN ;  A6SEH9, DED1_BOTFB ;  Q5A4E2, DED1_CANAL ;
DR   Q8TFK8, DED1_CANGA ;  Q2HBE7, DED1_CHAGB ;  Q1DJF0, DED1_COCIM ;
DR   P0CQ75, DED1_CRYNB ;  P0CQ74, DED1_CRYNJ ;  Q6BU54, DED1_DEBHA ;
DR   P0C2M6, DED1_EMENI ;  Q4I7K4, DED1_GIBZE ;  Q6CLR3, DED1_KLULA ;
DR   A5DZE6, DED1_LODEL ;  A4RHF1, DED1_MAGO7 ;  A1CXK7, DED1_NEOFI ;
DR   Q9P6U9, DED1_NEUCR ;  Q0UWA6, DED1_PHANO ;  A5DQS0, DED1_PICGU ;
DR   A3LQ01, DED1_PICST ;  O13370, DED1_SCHPO ;  A7EJY3, DED1_SCLS1 ;
DR   Q4P733, DED1_USTMA ;  A7TKR8, DED1_VANPO ;  Q6CB69, DED1_YARLI ;
DR   A6ZP47, DED1_YEAS7 ;  P06634, DED1_YEAST ;  Q75BS4, DHH1_ASHGO ;
DR   A1CJ18, DHH1_ASPCL ;  Q4WWD3, DHH1_ASPFU ;  A2QY39, DHH1_ASPNC ;
DR   Q2U5A2, DHH1_ASPOR ;  Q0CBE1, DHH1_ASPTN ;  A6RY31, DHH1_BOTFB ;
DR   Q5AAW3, DHH1_CANAL ;  Q6FQU5, DHH1_CANGA ;  Q2GQ93, DHH1_CHAGB ;
DR   Q1E5R1, DHH1_COCIM ;  P0CQ81, DHH1_CRYNB ;  P0CQ80, DHH1_CRYNJ ;
DR   Q58Z64, DHH1_CRYNV ;  Q6BJX6, DHH1_DEBHA ;  Q8SQK9, DHH1_ENCCU ;
DR   Q4HW67, DHH1_GIBZE ;  Q6CSZ7, DHH1_KLULA ;  A4R715, DHH1_MAGO7 ;
DR   A1D8G1, DHH1_NEOFI ;  Q7S5D9, DHH1_NEUCR ;  Q0U7S9, DHH1_PHANO ;
DR   A5DIP0, DHH1_PICGU ;  A3LWX3, DHH1_PICST ;  Q09181, DHH1_SCHPO ;
DR   A7TGU7, DHH1_VANPO ;  Q6C0X2, DHH1_YARLI ;  A6ZXG9, DHH1_YEAS7 ;
DR   P39517, DHH1_YEAST ;  Q04217, DHR1_YEAST ;  P36009, DHR2_YEAST ;
DR   O22899, DHX15_ARATH;  Q20875, DHX15_CAEEL;  Q54NJ4, DHX15_DICDI;
DR   O43143, DHX15_HUMAN;  O35286, DHX15_MOUSE;  Q5RAZ4, DHX15_PONAB;
DR   O42945, DHX15_SCHPO;  O17438, DHX15_STRPU;  O45244, DHX16_CAEEL;
DR   Q54MH3, DHX16_DICDI;  O60231, DHX16_HUMAN;  Q7YR39, DHX16_PANTR;
DR   Q767K6, DHX16_PIG  ;  Q7Z478, DHX29_HUMAN;  Q6PGC1, DHX29_MOUSE;
DR   A3KMI0, DHX29_XENLA;  Q2NKY8, DHX30_BOVIN;  Q5ZI74, DHX30_CHICK;
DR   Q7L2E3, DHX30_HUMAN;  Q99PU8, DHX30_MOUSE;  Q5R607, DHX30_PONAB;
DR   Q5BJS0, DHX30_RAT  ;  Q7L7V1, DHX32_HUMAN;  Q8BZS9, DHX32_MOUSE;
DR   Q5XH12, DHX32_XENLA;  Q9H6R0, DHX33_HUMAN;  Q80VY9, DHX33_MOUSE;
DR   Q14147, DHX34_HUMAN;  Q9DBV3, DHX34_MOUSE;  Q9BKQ8, DHX35_CAEEL;
DR   Q9H5Z1, DHX35_HUMAN;  Q5RBD4, DHX35_PONAB;  Q9H2U1, DHX36_HUMAN;
DR   Q8VHK9, DHX36_MOUSE;  Q8IY37, DHX37_HUMAN;  Q8IX18, DHX40_HUMAN;
DR   Q6PE54, DHX40_MOUSE;  Q5R864, DHX40_PONAB;  Q5XI69, DHX40_RAT  ;
DR   Q6P158, DHX57_HUMAN;  Q6P5D3, DHX57_MOUSE;  Q96C10, DHX58_HUMAN;
DR   Q99J87, DHX58_MOUSE;  Q38953, DHX8_ARATH ;  Q54F05, DHX8_DICDI ;
DR   Q14562, DHX8_HUMAN ;  A2A4P0, DHX8_MOUSE ;  Q28141, DHX9_BOVIN ;
DR   Q22307, DHX9_CAEEL ;  Q08211, DHX9_HUMAN ;  O70133, DHX9_MOUSE ;
DR   Q5R874, DHX9_PONAB ;  Q68FK8, DHX9_XENLA ;  Q75F95, DRS1_ASHGO ;
DR   A1CNV8, DRS1_ASPCL ;  Q4WRV2, DRS1_ASPFU ;  A2QAX7, DRS1_ASPNC ;
DR   Q2UQI6, DRS1_ASPOR ;  Q0CZN5, DRS1_ASPTN ;  A6RUH2, DRS1_BOTFB ;
DR   Q5ACK7, DRS1_CANAL ;  Q6FW42, DRS1_CANGA ;  P0C2N7, DRS1_CHAGB ;
DR   Q1E2B2, DRS1_COCIM ;  P0CQ93, DRS1_CRYNB ;  P0CQ92, DRS1_CRYNJ ;
DR   Q6BTL5, DRS1_DEBHA ;  Q4I830, DRS1_GIBZE ;  Q6CJV1, DRS1_KLULA ;
DR   A5DY34, DRS1_LODEL ;  A4QYM6, DRS1_MAGO7 ;  A1D1R8, DRS1_NEOFI ;
DR   P0C2N8, DRS1_NEUCR ;  Q0V1Z7, DRS1_PHANO ;  A5DKW3, DRS1_PICGU ;
DR   A3LSN3, DRS1_PICST ;  Q09903, DRS1_SCHPO ;  A7F4L5, DRS1_SCLS1 ;
DR   Q4P9P3, DRS1_USTMA ;  A7TJM9, DRS1_VANPO ;  Q6CEB8, DRS1_YARLI ;
DR   A7A0P8, DRS1_YEAS7 ;  P32892, DRS1_YEAST ;  O00148, DX39A_HUMAN;
DR   Q8VDW0, DX39A_MOUSE;  Q5U216, DX39A_RAT  ;  Q3T147, DX39B_BOVIN;
DR   Q18212, DX39B_CAEEL;  Q5WR10, DX39B_CANFA;  Q5ZHZ0, DX39B_CHICK;
DR   Q27268, DX39B_DROME;  Q13838, DX39B_HUMAN;  Q5TM17, DX39B_MACMU;
DR   Q9Z1N5, DX39B_MOUSE;  P60024, DX39B_PANTR;  Q29024, DX39B_PIG  ;
DR   Q5RE47, DX39B_PONAB;  Q63413, DX39B_RAT  ;  P32644, ECM32_YEAST;
DR   P0A4D7, EXP9_STRPN ;  P0A4D8, EXP9_STRR6 ;  A6QSQ0, FAL1_AJECN ;
DR   Q755W0, FAL1_ASHGO ;  A1C595, FAL1_ASPCL ;  Q4WEB4, FAL1_ASPFU ;
DR   A5AAE5, FAL1_ASPNC ;  Q2UAK1, FAL1_ASPOR ;  Q0CAS8, FAL1_ASPTN ;
DR   A6S4N4, FAL1_BOTFB ;  Q5A9Z6, FAL1_CANAL ;  Q6FJG1, FAL1_CANGA ;
DR   Q2GWJ5, FAL1_CHAGB ;  Q1DTB3, FAL1_COCIM ;  P0CQ73, FAL1_CRYNB ;
DR   P0CQ72, FAL1_CRYNJ ;  Q6BT27, FAL1_DEBHA ;  Q5AUL4, FAL1_EMENI ;
DR   Q4IAA0, FAL1_GIBZE ;  Q6CX73, FAL1_KLULA ;  A5DWJ1, FAL1_LODEL ;
DR   A4QU31, FAL1_MAGO7 ;  A1D071, FAL1_NEOFI ;  Q9P735, FAL1_NEUCR ;
DR   Q0UAT0, FAL1_PHANO ;  A5DE68, FAL1_PICGU ;  A3GFV3, FAL1_PICST ;
DR   Q10055, FAL1_SCHPO ;  A7EM88, FAL1_SCLS1 ;  Q4P184, FAL1_USTMA ;
DR   A7TEF4, FAL1_VANPO ;  Q6C347, FAL1_YARLI ;  A6ZXY5, FAL1_YEAS7 ;
DR   Q12099, FAL1_YEAST ;  Q3YK19, FANCJ_CHICK;  Q9BX63, FANCJ_HUMAN;
DR   Q5SXJ3, FANCJ_MOUSE;  Q8IYD8, FANCM_HUMAN;  Q8BGE5, FANCM_MOUSE;
DR   Q32LC7, G3BP1_BOVIN;  Q13283, G3BP1_HUMAN;  P97855, G3BP1_MOUSE;
DR   Q5RB87, G3BP1_PONAB;  P34689, GLH1_CAEEL ;  Q966L9, GLH2_CAEEL ;
DR   O01836, GLH3_CAEEL ;  O76743, GLH4_CAEEL ;  Q58083, H669_METJA ;
DR   Q89443, H962L_ASFB7;  P0C9A4, H962L_ASFK5;  Q8V9U2, H962L_ASFM2;
DR   P0C9A2, H962L_ASFP4;  P0C9A3, H962L_ASFWA;  Q74Z73, HAS1_ASHGO ;
DR   A1CIQ5, HAS1_ASPCL ;  Q4WQM4, HAS1_ASPFU ;  A2Q9T6, HAS1_ASPNC ;
DR   Q2UUN6, HAS1_ASPOR ;  Q0CZS8, HAS1_ASPTN ;  Q5AK59, HAS1_CANAL ;
DR   Q6FIL3, HAS1_CANGA ;  Q2GMX1, HAS1_CHAGB ;  Q1EA54, HAS1_COCIM ;
DR   P0CQ85, HAS1_CRYNB ;  P0CQ84, HAS1_CRYNJ ;  Q6BH93, HAS1_DEBHA ;
DR   Q5BBY1, HAS1_EMENI ;  Q4IEK8, HAS1_GIBZE ;  Q6CXB7, HAS1_KLULA ;
DR   A5E2Z9, HAS1_LODEL ;  A4R8B5, HAS1_MAGO7 ;  A1CW14, HAS1_NEOFI ;
DR   Q7S2N9, HAS1_NEUCR ;  Q0UR48, HAS1_PHANO ;  A5DID7, HAS1_PICGU ;
DR   A3LNR6, HAS1_PICST ;  Q09916, HAS1_SCHPO ;  Q4P6N0, HAS1_USTMA ;
DR   Q6C7D2, HAS1_YARLI ;  Q03532, HAS1_YEAST ;  A4KX71, HELI1_HVAVE;
DR   Q0E592, HELI1_SFAVA;  Q06VC2, HELI1_TNAVC;  P43329, HRPA_ECOLI ;
DR   P45018, HRPA_HAEIN ;  P37024, HRPB_ECOLI ;  O74465, HRR1_SCHPO ;
DR   Q5U526, I4A3A_XENLA;  O42226, I4A3B_XENLA;  P41382, IF410_TOBAC;
DR   Q40465, IF411_TOBAC;  Q40466, IF413_TOBAC;  Q40467, IF414_TOBAC;
DR   Q40468, IF415_TOBAC;  P41376, IF4A1_ARATH;  Q3SZ54, IF4A1_BOVIN;
DR   P60842, IF4A1_HUMAN;  Q4R8K5, IF4A1_MACFA;  P60843, IF4A1_MOUSE;
DR   P35683, IF4A1_ORYSJ;  A5A6N4, IF4A1_PANTR;  Q5R5F5, IF4A1_PONAB;
DR   P29562, IF4A1_RABIT;  P41377, IF4A2_ARATH;  Q3SZ65, IF4A2_BOVIN;
DR   Q8JFP1, IF4A2_CHICK;  Q14240, IF4A2_HUMAN;  Q4R4Y9, IF4A2_MACFA;
DR   P10630, IF4A2_MOUSE;  P41379, IF4A2_NICPL;  Q0E2Q3, IF4A2_ORYSJ;
DR   Q5R4X1, IF4A2_PONAB;  Q5RKI1, IF4A2_RAT  ;  Q9CAI7, IF4A3_ARATH;
DR   Q2NL22, IF4A3_BOVIN;  Q5ZM36, IF4A3_CHICK;  Q7ZVA6, IF4A3_DANRE;
DR   P38919, IF4A3_HUMAN;  Q4R3Q1, IF4A3_MACFA;  Q91VC3, IF4A3_MOUSE;
DR   P41380, IF4A3_NICPL;  Q6Z2Z4, IF4A3_ORYSJ;  A6M931, IF4A3_PIG  ;
DR   Q3B8Q2, IF4A3_RAT  ;  B5DG42, IF4A3_SALSA;  B5FZY7, IF4A3_TAEGU;
DR   B7ZTW1, IF4A3_XENTR;  Q40469, IF4A6_TOBAC;  Q40470, IF4A7_TOBAC;
DR   P41381, IF4A8_TOBAC;  Q40471, IF4A9_TOBAC;  A6R3R5, IF4A_AJECN ;
DR   Q75BL8, IF4A_ASHGO ;  A1CJT5, IF4A_ASPCL ;  Q4WX43, IF4A_ASPFU ;
DR   A2QEN5, IF4A_ASPNC ;  Q2UPY3, IF4A_ASPOR ;  Q0CXD0, IF4A_ASPTN ;
DR   A6RJ45, IF4A_BOTFB ;  P27639, IF4A_CAEEL ;  P87206, IF4A_CANAL ;
DR   Q6FQQ6, IF4A_CANGA ;  Q2HFP1, IF4A_CHAGB ;  Q1DQ20, IF4A_COCIM ;
DR   P0CQ71, IF4A_CRYNB ;  P0CQ70, IF4A_CRYNJ ;  O02494, IF4A_CRYPV ;
DR   Q6BRN4, IF4A_DEBHA ;  Q55D61, IF4A_DICDI ;  Q02748, IF4A_DROME ;
DR   Q5B948, IF4A_EMENI ;  Q8SQM5, IF4A_ENCCU ;  Q6CXT4, IF4A_KLULA ;
DR   Q25225, IF4A_LEIBR ;  A4HRK0, IF4A_LEIIN ;  O62591, IF4A_LEIMA ;
DR   A5DVM3, IF4A_LODEL ;  A4QVP2, IF4A_MAGO7 ;  Q41741, IF4A_MAIZE ;
DR   A1D7N3, IF4A_NEOFI ;  Q7RV88, IF4A_NEUCR ;  Q0UU86, IF4A_PHANO ;
DR   A5DB98, IF4A_PICGU ;  A3GFI4, IF4A_PICST ;  P47943, IF4A_SCHPO ;
DR   A7EGL7, IF4A_SCLS1 ;  Q38F76, IF4A_TRYB2 ;  Q4E162, IF4A_TRYCR ;
DR   Q4P331, IF4A_USTMA ;  A7TK55, IF4A_VANPO ;  P41378, IF4A_WHEAT ;
DR   Q6CDV4, IF4A_YARLI ;  A6ZQJ1, IF4A_YEAS7 ;  P10081, IF4A_YEAST ;
DR   Q9BYX4, IFIH1_HUMAN;  Q8R5F7, IFIH1_MOUSE;  B9DFG3, ISE2_ARATH ;
DR   O46072, KZ_DROME   ;  P15024, LMBD1_REOVD;  Q9WAB1, LMBD1_REOVJ;
DR   Q9WAB2, LMBD1_REOVL;  Q1LXK4, M10B1_DANRE;  Q1LXK5, M10B2_DANRE;
DR   Q9BXT6, M10L1_HUMAN;  Q99MV5, M10L1_MOUSE;  A6R9U4, MAK5_AJECN ;
DR   Q757I6, MAK5_ASHGO ;  A1CTL8, MAK5_ASPCL ;  Q4WMS3, MAK5_ASPFU ;
DR   A2QWW0, MAK5_ASPNC ;  Q2UMY7, MAK5_ASPOR ;  Q0CI35, MAK5_ASPTN ;
DR   Q59ZH9, MAK5_CANAL ;  Q6FY67, MAK5_CANGA ;  Q1E7Y4, MAK5_COCIM ;
DR   P0CQ91, MAK5_CRYNB ;  P0CQ90, MAK5_CRYNJ ;  Q6BV58, MAK5_DEBHA ;
DR   Q5BCI0, MAK5_EMENI ;  Q4IBS2, MAK5_GIBZE ;  Q6CTN7, MAK5_KLULA ;
DR   A5DUB2, MAK5_LODEL ;  A4REU9, MAK5_MAGO7 ;  A1DMT9, MAK5_NEOFI ;
DR   Q7RZH4, MAK5_NEUCR ;  Q0U6X2, MAK5_PHANO ;  A5DPU0, MAK5_PICGU ;
DR   A3GG51, MAK5_PICST ;  O74393, MAK5_SCHPO ;  A7EAY2, MAK5_SCLS1 ;
DR   A7TEG8, MAK5_VANPO ;  A6ZL85, MAK5_YEAS7 ;  P38112, MAK5_YEAST ;
DR   Q9HE09, MFH2_SCHPO ;  P24785, MLE_DROME  ;  P34498, MOG1_CAEEL ;
DR   Q09530, MOG5_CAEEL ;  Q0V8H6, MOV10_BOVIN;  Q5ZKD7, MOV10_CHICK;
DR   Q9HCE1, MOV10_HUMAN;  P23249, MOV10_MOUSE;  A6RCJ9, MRH4_AJECN ;
DR   Q755C5, MRH4_ASHGO ;  A1CSR1, MRH4_ASPCL ;  Q4X1X0, MRH4_ASPFU ;
DR   A2QZ71, MRH4_ASPNC ;  Q2TZH2, MRH4_ASPOR ;  Q0C9E8, MRH4_ASPTN ;
DR   Q59S59, MRH4_CANAL ;  Q6FJJ8, MRH4_CANGA ;  Q2H679, MRH4_CHAGB ;
DR   Q1E9B7, MRH4_COCIM ;  P0CR13, MRH4_CRYNB ;  P0CR12, MRH4_CRYNJ ;
DR   Q6BV94, MRH4_DEBHA ;  Q5AZY1, MRH4_EMENI ;  Q6CWQ5, MRH4_KLULA ;
DR   A5E5F7, MRH4_LODEL ;  A4QTC6, MRH4_MAGO7 ;  A1DGF2, MRH4_NEOFI ;
DR   Q7SBR1, MRH4_NEUCR ;  Q0U397, MRH4_PHANO ;  A5DR68, MRH4_PICGU ;
DR   A3LT90, MRH4_PICST ;  A7EWH6, MRH4_SCLS1 ;  A7TE77, MRH4_VANPO ;
DR   Q6C3J3, MRH4_YARLI ;  A6ZUB2, MRH4_YEAS7 ;  P53166, MRH4_YEAST ;
DR   Q750Q4, MS116_ASHGO;  Q4WRP2, MS116_ASPFU;  Q2UST1, MS116_ASPOR;
DR   Q5APM7, MS116_CANAL;  Q6FU81, MS116_CANGA;  Q6CQA1, MS116_KLULA;
DR   A5DTK7, MS116_LODEL;  Q0UG00, MS116_PHANO;  A5DEZ5, MS116_PICGU;
DR   O13622, MS116_SCHPO;  P15424, MS116_YEAST;  P47047, MTR4_YEAST ;
DR   O72904, NPH2_FOWPN ;  Q98218, NPH2_MCV1  ;  Q9YW06, NPH2_MSEPV ;
DR   Q9Q8Q2, NPH2_MYXVL ;  Q9Q927, NPH2_RFVKA ;  O57193, NPH2_VACCA ;
DR   P20502, NPH2_VACCC ;  Q9JFC3, NPH2_VACCT ;  P12927, NPH2_VACCW ;
DR   P33051, NPH2_VAR67 ;  Q04350, POLB_CHPVE ;  Q9YTU2, POLB_CHPVU ;
DR   Q6PLS1, POLG_ASGVK ;  P36309, POLG_ASGVP ;  Q96662, POLG_BVDVC ;
DR   P19711, POLG_BVDVN ;  Q01499, POLG_BVDVS ;  Q1KZ59, POLG_CILVC ;
DR   P19712, POLG_CSFVA ;  P21530, POLG_CSFVB ;  P27909, POLG_DEN1B ;
DR   P33478, POLG_DEN1S ;  P17763, POLG_DEN1W ;  P29990, POLG_DEN26 ;
DR   P29991, POLG_DEN27 ;  P14337, POLG_DEN28 ;  P07564, POLG_DEN2J ;
DR   P14340, POLG_DEN2N ;  P12823, POLG_DEN2P ;  Q9WDA6, POLG_DEN2Q ;
DR   P27914, POLG_DEN2T ;  Q99D35, POLG_DEN3C ;  Q5UB51, POLG_DEN3I ;
DR   Q6YMS3, POLG_DEN3M ;  P27915, POLG_DEN3P ;  Q6YMS4, POLG_DEN3S ;
DR   P09866, POLG_DEN4D ;  Q2YHF2, POLG_DEN4H ;  Q58HT7, POLG_DEN4P ;
DR   Q5UCB8, POLG_DEN4S ;  Q2YHF0, POLG_DEN4T ;  Q69422, POLG_GBVB  ;
DR   P26664, POLG_HCV1  ;  Q5I2N3, POLG_HCV6A ;  Q68749, POLG_HCVBB ;
DR   P26663, POLG_HCVBK ;  Q9WMX2, POLG_HCVCO ;  O39929, POLG_HCVED ;
DR   O39927, POLG_HCVEU ;  O39928, POLG_HCVEV ;  P27958, POLG_HCVH  ;
DR   Q81754, POLG_HCVH9 ;  Q913D4, POLG_HCVIN ;  Q03463, POLG_HCVJ1 ;
DR   O92972, POLG_HCVJ4 ;  P26660, POLG_HCVJ6 ;  P26661, POLG_HCVJ8 ;
DR   P26662, POLG_HCVJA ;  Q99IB8, POLG_HCVJF ;  Q68801, POLG_HCVJK ;
DR   Q68798, POLG_HCVJL ;  Q9DHD6, POLG_HCVJP ;  Q00269, POLG_HCVJT ;
DR   Q81495, POLG_HCVK3 ;  Q81258, POLG_HCVNZ ;  Q913V3, POLG_HCVR6 ;
DR   O91936, POLG_HCVSA ;  O92529, POLG_HCVT5 ;  Q81487, POLG_HCVTR ;
DR   P29846, POLG_HCVTW ;  Q9QAX1, POLG_HCVVA ;  O92530, POLG_HCVVN ;
DR   O92531, POLG_HCVVO ;  O92532, POLG_HCVVP ;  P27395, POLG_JAEV1 ;
DR   P19110, POLG_JAEV5 ;  P32886, POLG_JAEVJ ;  P14403, POLG_JAEVN ;
DR   P14335, POLG_KUNJM ;  P29837, POLG_LANVT ;  P22338, POLG_LIV   ;
DR   P33515, POLG_MCFA  ;  Q91TW9, POLG_MRFVC ;  P05769, POLG_MVEV5 ;
DR   Q04538, POLG_POWVL ;  P09732, POLG_STEVM ;  Q01299, POLG_TBEVH ;
DR   P07720, POLG_TBEVS ;  P14336, POLG_TBEVW ;  P06935, POLG_WNV   ;
DR   P03314, POLG_YEFV1 ;  Q6DV88, POLG_YEFVA ;  Q6J3P1, POLG_YEFVC ;
DR   Q074N0, POLG_YEFVE ;  Q89277, POLG_YEFVF ;  Q98803, POLG_YEFVI ;
DR   Q1X881, POLG_YEFVN ;  Q9YRV3, POLG_YEFVT ;  Q1X880, POLG_YEFVU ;
DR   Q86924, POLN_AURAV ;  P87515, POLN_BFV   ;  Q5XXP4, POLN_CHIK3 ;
DR   Q8JUX6, POLN_CHIKS ;  Q306W6, POLN_EEEV1 ;  Q306W8, POLN_EEEV8 ;
DR   Q4QXJ8, POLN_EEEVF ;  P36327, POLN_EEVV3 ;  Q8V294, POLN_EEVVC ;
DR   Q9WJC7, POLN_EEVVM ;  P36328, POLN_EEVVP ;  P27282, POLN_EEVVT ;
DR   Q5Y389, POLN_GETV  ;  Q8QZ73, POLN_MAYAB ;  P13886, POLN_ONNVG ;
DR   O90370, POLN_ONNVI ;  O90368, POLN_ONNVS ;  P13887, POLN_RRVN  ;
DR   Q6X2U4, POLN_RUBVB ;  Q6X2U2, POLN_RUBVC ;  Q9J6K9, POLN_RUBVD ;
DR   Q86500, POLN_RUBVM ;  Q8BCR0, POLN_RUBVN ;  Q99IE7, POLN_RUBVO ;
DR   O40955, POLN_RUBVR ;  P13889, POLN_RUBVT ;  Q99IE5, POLN_RUBVV ;
DR   Q9JGL0, POLN_SAGV  ;  P08411, POLN_SFV   ;  P27283, POLN_SINDO ;
DR   P03317, POLN_SINDV ;  Q8QL53, POLN_SLDV  ;  Q8JJX1, POLN_SPDV  ;
DR   P13896, POLN_WEEV  ;  Q03319, PRH1_SCHPO ;  Q9P7C7, PRP11_SCHPO;
DR   Q17R09, PRP16_BOVIN;  Q92620, PRP16_HUMAN;  Q9P774, PRP16_SCHPO;
DR   P15938, PRP16_YEAST;  O42643, PRP22_SCHPO;  P24384, PRP22_YEAST;
DR   A1CHL3, PRP28_ASPCL;  Q4WPE9, PRP28_ASPFU;  A2QIL2, PRP28_ASPNC;
DR   Q2UH00, PRP28_ASPOR;  Q0CLX0, PRP28_ASPTN;  A6RJA2, PRP28_BOTFB;
DR   Q59W52, PRP28_CANAL;  Q6FM43, PRP28_CANGA;  Q2HEB0, PRP28_CHAGB;
DR   Q1DMX8, PRP28_COCIM;  P0CQ89, PRP28_CRYNB;  P0CQ88, PRP28_CRYNJ;
DR   Q6BLU9, PRP28_DEBHA;  Q5BCU6, PRP28_EMENI;  Q4I7F9, PRP28_GIBZE;
DR   Q6CT49, PRP28_KLULA;  A5DU73, PRP28_LODEL;  A4RK80, PRP28_MAGO7;
DR   A1CX72, PRP28_NEOFI;  Q7SEL0, PRP28_NEUCR;  Q0UWC8, PRP28_PHANO;
DR   A5DF03, PRP28_PICGU;  A3LNL1, PRP28_PICST;  Q9Y7T7, PRP28_SCHPO;
DR   A7EGG4, PRP28_SCLS1;  Q6C024, PRP28_YARLI;  P23394, PRP28_YEAST;
DR   P20095, PRP2_YEAST ;  P53131, PRP43_YEAST;  Q754U8, PRP5_ASHGO ;
DR   A1CQA9, PRP5_ASPCL ;  Q4WT99, PRP5_ASPFU ;  A2QQA8, PRP5_ASPNC ;
DR   Q2U2J6, PRP5_ASPOR ;  Q0D1K3, PRP5_ASPTN ;  A6RW79, PRP5_BOTFB ;
DR   Q5ADL0, PRP5_CANAL ;  Q6FML5, PRP5_CANGA ;  Q2HAD8, PRP5_CHAGB ;
DR   Q1DHB2, PRP5_COCIM ;  P0CQ99, PRP5_CRYNB ;  P0CQ98, PRP5_CRYNJ ;
DR   Q6BML1, PRP5_DEBHA ;  Q5BDW4, PRP5_EMENI ;  Q4IP34, PRP5_GIBZE ;
DR   Q6CKI1, PRP5_KLULA ;  A5E058, PRP5_LODEL ;  A4RN46, PRP5_MAGO7 ;
DR   A1D373, PRP5_NEOFI ;  Q7SH33, PRP5_NEUCR ;  Q0UN57, PRP5_PHANO ;
DR   A5DDF4, PRP5_PICGU ;  A3LQ55, PRP5_PICST ;  A7ENE0, PRP5_SCLS1 ;
DR   Q4PFD9, PRP5_USTMA ;  A7TJK8, PRP5_VANPO ;  Q6CCZ1, PRP5_YARLI ;
DR   A6ZLH6, PRP5_YEAS7 ;  P21372, PRP5_YEAST ;  P0C6W1, R1AB_BC133 ;
DR   P0C6V9, R1AB_BC279 ;  P0C6W0, R1AB_BC512 ;  P0C6W2, R1AB_BCHK3 ;
DR   P0C6W3, R1AB_BCHK4 ;  P0C6W4, R1AB_BCHK5 ;  P0C6W5, R1AB_BCHK9 ;
DR   P0C6W6, R1AB_BCRP3 ;  P0C6V7, R1AB_BEV   ;  P0C6V8, R1AB_BRV1  ;
DR   Q08534, R1AB_BYVU  ;  P0C6W7, R1AB_CVBEN ;  P0C6W8, R1AB_CVBLU ;
DR   P0C6W9, R1AB_CVBM  ;  P0C6X0, R1AB_CVBQ  ;  P0C6X1, R1AB_CVH22 ;
DR   P0C6X2, R1AB_CVHN1 ;  P0C6X3, R1AB_CVHN2 ;  P0C6X4, R1AB_CVHN5 ;
DR   P0C6X5, R1AB_CVHNL ;  P0C6X6, R1AB_CVHOC ;  P0C6X7, R1AB_CVHSA ;
DR   P0C6X8, R1AB_CVM2  ;  P0C6X9, R1AB_CVMA5 ;  P0C6Y0, R1AB_CVMJH ;
DR   P0C6Y5, R1AB_CVPPU ;  Q98VG9, R1AB_FIPV  ;  O71189, R1AB_GLRV3 ;
DR   P0C6Y1, R1AB_IBVB  ;  P0C6Y2, R1AB_IBVBC ;  P0C6Y3, R1AB_IBVM  ;
DR   Q83045, R1AB_LIYV9 ;  P0C6Y4, R1AB_PEDV7 ;  Q008X6, R1AB_WBV24 ;
DR   O71188, R1A_GLRV3  ;  Q83044, R1A_LIYV   ;  Q64962, RDRP_ASPVP ;
DR   Q65667, RDRP_BNYVS ;  Q9DRA1, RDRP_BOTVF ;  Q6YNQ7, RDRP_BOTVX ;
DR   P69514, RDRP_CGMVS ;  Q91QZ3, RDRP_CLBVS ;  P37987, RDRP_CVB   ;
DR   P22168, RDRP_FXMV  ;  Q8UZB6, RDRP_GFKVM ;  Q67704, RDRP_GVAIS ;
DR   Q67724, RDRP_HASV  ;  Q918W3, RDRP_ICRSV ;  B1PS76, RDRP_LOLV  ;
DR   P27328, RDRP_LSV   ;  P27327, RDRP_LVX   ;  Q9YRB3, RDRP_NCBVS ;
DR   P15095, RDRP_NMV   ;  P89659, RDRP_ORSVC ;  Q84133, RDRP_ORSVS ;
DR   Q07518, RDRP_P1AMV ;  Q84687, RDRP_PCV87 ;  P89657, RDRP_PMMVJ ;
DR   P29098, RDRP_PMMVS ;  Q9QBU0, RDRP_PMTVS ;  P20951, RDRP_PMV   ;
DR   P17965, RDRP_PVMR  ;  P22657, RDRP_PVSP  ;  P09395, RDRP_PVX   ;
DR   P22591, RDRP_PVXCP ;  Q07630, RDRP_PVXHB ;  P17779, RDRP_PVXX3 ;
DR   Q05983, RDRP_RBDVR ;  Q89249, RDRP_SBWMN ;  P89202, RDRP_SHMV  ;
DR   Q04575, RDRP_SHVX  ;  P28897, RDRP_SMYEA ;  Q6YI57, RDRP_SSDRV ;
DR   P18339, RDRP_TMGMV ;  P90211, RDRP_TMOB  ;  P03586, RDRP_TMV   ;
DR   Q9YQ08, RDRP_TMVB  ;  P30738, RDRP_TMVKR ;  O93058, RDRP_TMVOM ;
DR   Q98745, RDRP_TMVRA ;  Q9Q1T8, RDRP_TOMK1 ;  P89676, RDRP_TOMK2 ;
DR   P03587, RDRP_TOML  ;  Q9YKD6, RDRP_TOMS1 ;  Q9J942, RDRP_TRVPP ;
DR   P05079, RDRP_TRVPS ;  Q88920, RDRP_TVCV  ;  P09498, RDRP_WCMVM ;
DR   P15402, RDRP_WCMVO ;  Q66220, RDRP_YOMV  ;  Q8GY84, RH10_ARATH ;
DR   Q7Y183, RH10_ORYSJ ;  Q8LA13, RH11_ARATH ;  Q9M2E0, RH12_ARATH ;
DR   Q109G2, RH12_ORYSJ ;  Q93Y39, RH13_ARATH ;  A2XVF7, RH13_ORYSI ;
DR   A3AVH5, RH13_ORYSJ ;  Q8H136, RH14_ARATH ;  Q5VQL1, RH14_ORYSJ ;
DR   Q56XG6, RH15_ARATH ;  Q5JK84, RH15_ORYSJ ;  Q9SW44, RH16_ARATH ;
DR   Q6ATJ8, RH16_ORYSJ ;  Q7XJN0, RH17_ARATH ;  Q0DLB9, RH17_ORYSJ ;
DR   Q9FLB0, RH18_ARATH ;  Q761Z9, RH18_ORYSJ ;  Q7FGZ2, RH1_ARATH  ;
DR   P85441, RH1_CATRO  ;  Q0DWT8, RH1_ORYSJ  ;  Q9C718, RH20_ARATH ;
DR   Q5QMN3, RH20_ORYSJ ;  P93008, RH21_ARATH ;  Q53RK8, RH21_ORYSJ ;
DR   Q944S1, RH22_ARATH ;  Q6H601, RH22_ORYSJ ;  O22907, RH24_ARATH ;
DR   Q10MH8, RH24_ORYSJ ;  Q94C75, RH25_ARATH ;  Q5ZBH5, RH25_ORYSJ ;
DR   Q9FNM7, RH26_ARATH ;  Q0JL73, RH26_ORYSJ ;  Q9SB89, RH27_ARATH ;
DR   Q84T03, RH27_ORYSJ ;  Q9ZRZ8, RH28_ARATH ;  Q0INC5, RH28_ORYSJ ;
DR   O49289, RH29_ARATH ;  A2YV85, RH29_ORYSI ;  A3BT52, RH29_ORYSJ ;
DR   Q94A52, RH2_ARATH  ;  Q5VNM3, RH2_ORYSJ  ;  Q8W4R3, RH30_ARATH ;
DR   Q5N7W4, RH30_ORYSJ ;  Q9FFQ1, RH31_ARATH ;  Q0DBU5, RH31_ORYSJ ;
DR   Q9FFT9, RH32_ARATH ;  Q0D622, RH32_ORYSJ ;  O80792, RH33_ARATH ;
DR   Q9C8J1, RH34_ARATH ;  Q10I26, RH34_ORYSJ ;  Q0E3X4, RH35A_ORYSJ;
DR   Q5Z6G5, RH35B_ORYSJ;  Q9LU46, RH35_ARATH ;  Q9SA27, RH36_ARATH ;
DR   Q8L4E9, RH36_ORYSJ ;  Q84W89, RH37_ARATH ;  Q75HJ0, RH37_ORYSJ ;
DR   Q93ZG7, RH38_ARATH ;  Q10RI7, RH38_ORYSJ ;  Q56X76, RH39_ARATH ;
DR   Q5VRY0, RH39_ORYSJ ;  Q8L7S8, RH3_ARATH  ;  Q0DM51, RH3_ORYSJ  ;
DR   Q9SQV1, RH40_ARATH ;  Q5JKF2, RH40_ORYSJ ;  Q3EBD3, RH41_ARATH ;
DR   Q0E2Z7, RH41_ORYSJ ;  Q8H0U8, RH42_ARATH ;  Q84UQ1, RH42_ORYSJ ;
DR   Q9SZB4, RH43_ARATH ;  Q9FZ92, RH44_ARATH ;  Q9SF41, RH45_ARATH ;
DR   Q0J7Y8, RH45_ORYSJ ;  Q9LYJ9, RH46_ARATH ;  Q6H874, RH47A_ORYSJ;
DR   Q10PV9, RH47B_ORYSJ;  Q8W4E1, RH47_ARATH ;  Q9C8S9, RH48_ARATH ;
DR   Q6K7R9, RH48_ORYSJ ;  Q8GXD6, RH49_ARATH ;  Q8GUG7, RH50_ARATH ;
DR   Q0DVX2, RH50_ORYSJ ;  Q9LIH9, RH51_ARATH ;  Q0DBS1, RH51_ORYSJ ;
DR   Q0DB53, RH52A_ORYSJ;  Q6Z4K6, RH52B_ORYSJ;  Q2R1M8, RH52C_ORYSJ;
DR   Q9M2F9, RH52_ARATH ;  Q9LUW5, RH53_ARATH ;  Q0D8N0, RH53_ORYSJ ;
DR   Q9FVV4, RH55_ARATH ;  Q9LFN6, RH56_ARATH ;  Q0JM17, RH56_ORYSJ ;
DR   Q84TG1, RH57_ARATH ;  Q5K5B6, RH57_ORYSJ ;  Q3E9C3, RH58_ARATH ;
DR   Q0JFN7, RH58_ORYSJ ;  Q9C551, RH5_ARATH  ;  Q6YS30, RH5_ORYSJ  ;
DR   Q94BV4, RH6_ARATH  ;  Q7XMK8, RH6_ORYSJ  ;  Q39189, RH7_ARATH  ;
DR   Q650T9, RH7_ORYSJ  ;  Q41382, RH7_SPIOL  ;  Q8RXK6, RH8_ARATH  ;
DR   Q6H7S2, RH8_ORYSJ  ;  Q9LUW6, RH9_ARATH  ;  Q0ILZ4, RH9_ORYSJ  ;
DR   P34305, RHA2_CAEEL ;  A6VKC3, RHLB_ACTSZ ;  A0KEG9, RHLB_AERHH ;
DR   A4STJ7, RHLB_AERS4 ;  B6EPA4, RHLB_ALISL ;  A8ACT3, RHLB_CITK8 ;
DR   A7ZTY2, RHLB_ECO24 ;  B7UMN5, RHLB_ECO27 ;  B7MGJ1, RHLB_ECO45 ;
DR   B7L8B6, RHLB_ECO55 ;  Q8XAT4, RHLB_ECO57 ;  B5YY28, RHLB_ECO5E ;
DR   B7NTG2, RHLB_ECO7I ;  B7MR01, RHLB_ECO81 ;  B7M5C7, RHLB_ECO8A ;
DR   C4ZZ48, RHLB_ECOBW ;  B1X9Z4, RHLB_ECODH ;  A8A6N4, RHLB_ECOHS ;
DR   A1AHV0, RHLB_ECOK1 ;  Q0TAU3, RHLB_ECOL5 ;  P0A8J9, RHLB_ECOL6 ;
DR   B1IWC0, RHLB_ECOLC ;  P0A8J8, RHLB_ECOLI ;  B7NF85, RHLB_ECOLU ;
DR   B6I4B6, RHLB_ECOSE ;  B1LLV3, RHLB_ECOSM ;  Q1R4F9, RHLB_ECOUT ;
DR   A4WG30, RHLB_ENT38 ;  A7MQI2, RHLB_ENTS8 ;  Q6CZD9, RHLB_ERWCT ;
DR   B2VG58, RHLB_ERWT9 ;  B7LU75, RHLB_ESCF3 ;  A5UDI1, RHLB_HAEIE ;
DR   A5UI36, RHLB_HAEIG ;  P44922, RHLB_HAEIN ;  Q0I1X0, RHLB_HAES1 ;
DR   B0UUZ9, RHLB_HAES2 ;  C4K8M8, RHLB_HAMD5 ;  Q5QYF8, RHLB_IDILO ;
DR   B5XYY9, RHLB_KLEP3 ;  A6TGG9, RHLB_KLEP7 ;  Q65RG7, RHLB_MANSM ;
DR   Q9CJS1, RHLB_PASMU ;  C6DHF5, RHLB_PECCP ;  Q7MYL2, RHLB_PHOLL ;
DR   Q6LLL5, RHLB_PHOPR ;  B4F1V3, RHLB_PROMH ;  Q15N18, RHLB_PSEA6 ;
DR   B7UUT0, RHLB_PSEA8 ;  Q02S21, RHLB_PSEAB ;  Q9HXE5, RHLB_PSEAE ;
DR   Q88NB7, RHLB_PSEPK ;  Q887N8, RHLB_PSESM ;  A1SZG4, RHLB_PSYIN ;
DR   B5EZ40, RHLB_SALA4 ;  A9MJ29, RHLB_SALAR ;  Q57HT6, RHLB_SALCH ;
DR   B5FN74, RHLB_SALDC ;  B5QVH2, RHLB_SALEP ;  B5RFS3, RHLB_SALG2 ;
DR   B4TB13, RHLB_SALHS ;  B4SZ26, RHLB_SALNS ;  A9MXF3, RHLB_SALPB ;
DR   C0Q2V9, RHLB_SALPC ;  B5BIS9, RHLB_SALPK ;  B4TNT3, RHLB_SALSV ;
DR   P0A2P1, RHLB_SALTI ;  P0A2P0, RHLB_SALTY ;  A8G828, RHLB_SERP5 ;
DR   A1SAL1, RHLB_SHEAM ;  B8E670, RHLB_SHEB2 ;  A3D9I5, RHLB_SHEB5 ;
DR   A6WTD3, RHLB_SHEB8 ;  A9L5D5, RHLB_SHEB9 ;  Q12S35, RHLB_SHEDO ;
DR   Q088J2, RHLB_SHEFN ;  B0TJ29, RHLB_SHEHH ;  A3Q9R3, RHLB_SHELP ;
DR   Q8EJQ5, RHLB_SHEON ;  A8GZJ0, RHLB_SHEPA ;  A4YB09, RHLB_SHEPC ;
DR   B8CHZ1, RHLB_SHEPW ;  A0KS84, RHLB_SHESA ;  A8G0U0, RHLB_SHESH ;
DR   Q0HN76, RHLB_SHESM ;  Q0HQL1, RHLB_SHESR ;  A1RFB3, RHLB_SHESW ;
DR   B1KQF6, RHLB_SHEWM ;  B2TU12, RHLB_SHIB3 ;  Q31UK5, RHLB_SHIBS ;
DR   Q329V8, RHLB_SHIDS ;  Q0SYX0, RHLB_SHIF8 ;  P0A8K0, RHLB_SHIFL ;
DR   Q3YVI4, RHLB_SHISS ;  Q2NQB2, RHLB_SODGM ;  C4LB49, RHLB_TOLAT ;
DR   A5F3R4, RHLB_VIBC3 ;  Q9KV52, RHLB_VIBCH ;  C3LQR1, RHLB_VIBCM ;
DR   Q5E8U5, RHLB_VIBF1 ;  B5FF87, RHLB_VIBFM ;  A7MXT4, RHLB_VIBHB ;
DR   Q87KH5, RHLB_VIBPA ;  B7VME9, RHLB_VIBSL ;  Q8DDN6, RHLB_VIBVU ;
DR   Q7MGP7, RHLB_VIBVY ;  Q8PFZ3, RHLB_XANAC ;  Q3BNH8, RHLB_XANC5 ;
DR   Q4UPY5, RHLB_XANC8 ;  B0RWT6, RHLB_XANCB ;  Q8P4D4, RHLB_XANCP ;
DR   Q5GUR8, RHLB_XANOR ;  Q9PA24, RHLB_XYLFA ;  Q879Y6, RHLB_XYLFT ;
DR   A7FD47, RHLB_YERP3 ;  Q1CBQ4, RHLB_YERPA ;  B2K046, RHLB_YERPB ;
DR   Q8ZAD8, RHLB_YERPE ;  Q1CNK3, RHLB_YERPN ;  A4TRC8, RHLB_YERPP ;
DR   Q66G19, RHLB_YERPS ;  B1JQ11, RHLB_YERPY ;  P25888, RHLE_ECOLI ;
DR   Q75AE1, ROK1_ASHGO ;  A1CNK1, ROK1_ASPCL ;  Q4WRH5, ROK1_ASPFU ;
DR   A2QAB5, ROK1_ASPNC ;  Q2UQW3, ROK1_ASPOR ;  Q0CMB0, ROK1_ASPTN ;
DR   Q9Y7C4, ROK1_CANAL ;  Q6FN65, ROK1_CANGA ;  Q2HCV7, ROK1_CHAGB ;
DR   Q1E306, ROK1_COCIM ;  P0CR05, ROK1_CRYNB ;  P0CR04, ROK1_CRYNJ ;
DR   Q6BP45, ROK1_DEBHA ;  Q5BET6, ROK1_EMENI ;  Q4IPI1, ROK1_GIBZE ;
DR   Q6CSW1, ROK1_KLULA ;  A5E1N2, ROK1_LODEL ;  A4RMV8, ROK1_MAGO7 ;
DR   A1D1E3, ROK1_NEOFI ;  Q7SFC8, ROK1_NEUCR ;  A5DIX5, ROK1_PICGU ;
DR   A3GHW9, ROK1_PICST ;  Q09775, ROK1_SCHPO ;  A7TT88, ROK1_VANPO ;
DR   Q6CDS6, ROK1_YARLI ;  A6ZU15, ROK1_YEAS7 ;  P45818, ROK1_YEAST ;
DR   P19811, RPOA_EAVBU ;  Q06502, RPOA_LDVC  ;  Q83017, RPOA_LDVP  ;
DR   Q9YN02, RPOA_PRRS1 ;  Q8B912, RPOA_PRRSB ;  Q04561, RPOA_PRRSL ;
DR   Q9WJB2, RPOA_PRRSR ;  A0MD28, RPOA_PRRSS ;  Q68772, RPOA_SHFV  ;
DR   Q8GYD9, SDE3_ARATH ;  P42285, SK2L2_HUMAN;  Q9CZU3, SK2L2_MOUSE;
DR   P35207, SKI2_YEAST ;  P53327, SLH1_YEAST ;  P38935, SMBP2_HUMAN;
DR   Q60560, SMBP2_MESAU;  P40694, SMBP2_MOUSE;  Q9EQN5, SMBP2_RAT  ;
DR   Q16JS8, SPNE_AEDAE ;  Q7QCW2, SPNE_ANOGA ;  B0XDC4, SPNE_CULQU ;
DR   B3M383, SPNE_DROAN ;  B3P3W1, SPNE_DROER ;  B4JT42, SPNE_DROGR ;
DR   Q9VF26, SPNE_DROME ;  B4K5R2, SPNE_DROMO ;  B4GEU5, SPNE_DROPE ;
DR   Q296Q5, SPNE_DROPS ;  B4HLH4, SPNE_DROSE ;  B4LX81, SPNE_DROVI ;
DR   B4NBB0, SPNE_DROWI ;  B4PRJ9, SPNE_DROYA ;  P21507, SRMB_ECOLI ;
DR   P44701, SRMB_HAEIN ;  A7TLA0, SUB21_VANPO;  A7TJT7, SUB22_VANPO;
DR   A6R603, SUB2_AJECN ;  Q759L6, SUB2_ASHGO ;  A1CMQ7, SUB2_ASPCL ;
DR   Q4WCW2, SUB2_ASPFU ;  A2R0B5, SUB2_ASPNC ;  Q2U6P7, SUB2_ASPOR ;
DR   Q0CGJ9, SUB2_ASPTN ;  Q6FL17, SUB2_CANGA ;  Q2H4D0, SUB2_CHAGB ;
DR   Q1DI07, SUB2_COCIM ;  P0CQ97, SUB2_CRYNB ;  P0CQ96, SUB2_CRYNJ ;
DR   Q6BME5, SUB2_DEBHA ;  Q5ASK8, SUB2_EMENI ;  Q6CM95, SUB2_KLULA ;
DR   A5E3W5, SUB2_LODEL ;  A4RBS3, SUB2_MAGO7 ;  A1DL85, SUB2_NEOFI ;
DR   Q0TXZ2, SUB2_PHANO ;  A5DDN0, SUB2_PICGU ;  A3LST5, SUB2_PICST ;
DR   O13792, SUB2_SCHPO ;  A7EIX7, SUB2_SCLS1 ;  Q6CH90, SUB2_YARLI ;
DR   A6ZXP4, SUB2_YEAS7 ;  Q07478, SUB2_YEAST ;  Q61SU7, SUV3_CAEBR ;
DR   Q17828, SUV3_CAEEL ;  Q5ZJT0, SUV3_CHICK ;  A4IG62, SUV3_DANRE ;
DR   Q9VN03, SUV3_DROME ;  Q295E6, SUV3_DROPS ;  Q8IYB8, SUV3_HUMAN ;
DR   Q80YD1, SUV3_MOUSE ;  Q5EBA1, SUV3_RAT   ;  O74727, SUV3_SACDO ;
DR   O94445, SUV3_SCHPO ;  P32580, SUV3_YEAST ;  B8A4F4, TDRD9_DANRE;
DR   Q8NDG6, TDRD9_HUMAN;  Q14BI7, TDRD9_MOUSE;  Q3MHU3, TDRD9_RAT  ;
DR   Q9U2G0, U520_CAEEL ;  Q9VUV9, U520_DROME ;  O75643, U520_HUMAN ;
DR   O94536, UCP12_SCHPO;  P09052, VASA1_DROME;  Q89525, VF113_ASFB7;
DR   P0C9A7, VF113_ASFK5;  Q89425, VF113_ASFM2;  P0C9A5, VF113_ASFP4;
DR   P0C9A6, VF113_ASFWA;  Q65191, VF509_ASFB7;  P0C9B0, VF509_ASFK5;
DR   Q89576, VF509_ASFM2;  P0C9A8, VF509_ASFP4;  P0C9A9, VF509_ASFWA;
DR   Q89581, VF706_ASFB7;  P0C9B3, VF706_ASFK5;  Q89926, VF706_ASFM2;
DR   P0C9B1, VF706_ASFP4;  P0C9B2, VF706_ASFWA;  Q58900, Y1505_METJA;
DR   Q8CRP6, Y1679_STAES;  Q5HME0, Y1688_STAEQ;  Q7A4G0, Y1885_STAAN;
DR   Q2YUH3, Y1965_STAAB;  Q6G7M9, Y1985_STAAS;  Q7A0D2, Y2004_STAAW;
DR   Q2FF45, Y2037_STAA3;  Q5HEB9, Y2072_STAAC;  Q99SH6, Y2081_STAAM;
DR   Q6GEZ3, Y2168_STAAR;  Q2FWH5, Y2316_STAA8;  P52271, Y308_MYCGE ;
DR   P47664, Y425_MYCGE ;  P75335, Y443_MYCPN ;  Q9W3Y5, Y4443_DROME;
DR   P75172, Y623_MYCPN ;  Q49Z29, Y802_STAS1 ;  Q86B47, Y8611_DROME;
DR   Q4L7W0, Y956_STAHJ ;  O34750, YFML_BACSU ;  O74356, YH16_SCHPO ;
DR   Q9HDY4, YK16_SCHPO ;  Q9HE06, YK99_SCHPO ;  Q5UR22, YL364_MIMIV;
DR   Q5UQW0, YL377_MIMIV;  Q5UQ46, YL396_MIMIV;  Q06698, YL419_YEAST;
DR   Q5UQ98, YL538_MIMIV;  Q5UQ96, YL540_MIMIV;  P34668, YO12_CAEEL ;
DR   Q5UPX0, YR290_MIMIV;  Q5UQU2, YR350_MIMIV;  Q5UR20, YR366_MIMIV;
DR   Q5UQD1, YR458_MIMIV;  Q7T6X3, YR563_MIMIV;  Q9H6S0, YTDC2_HUMAN;
DR   B2RR83, YTDC2_MOUSE;
//
ID   3.6.5.1
DE   Heterotrimeric G-protein GTPase.
CA   GTP + H(2)O = GDP + phosphate.
CC   -!- This group comprises GTP-hydrolyzing systems, where GTP and GDP
CC       alternate in binding.
CC   -!- This group includes stimulatory and inhibitory G-proteins such as
CC       G(s), G(i), G(o) and G(olf), targeting adenylate cyclase and/or K(+)
CC       and Ca(2+) channels; G(q) stimulating phospholipase C; transducin
CC       activating cGMP phosphodiesterase; gustducin activating cAMP
CC       phosphodiesterase.
CC   -!- G(olf) is instrumental in odor perception, transducin in vision and
CC       gustducin in taste recognition.
CC   -!- At least 16 different alpha subunits (39-52 kDa), 5 beta subunits (36
CC       kDa) and 12 gamma subunits (6-9 kDa) are known.
CC   -!- Formerly EC 3.6.1.46.
PR   PROSITE; PDOC01002;
//
ID   3.6.5.2
DE   Small monomeric GTPase.
CA   GTP + H(2)O = GDP + phosphate.
CC   -!- A family of about 50 enzymes with a molecular mass of 21 kDa that are
CC       distantly related to the alpha-subunit of EC 3.6.1.46.
CC   -!- Involved in cell-growth regulation (Ras subfamily), membrane vesicle
CC       traffic and uncoating (Rab and ARF subfamilies), nuclear protein
CC       import (Ran subfamily) and organization of the cytoskeleton (Rho and
CC       Rac subfamilies).
CC   -!- Formerly EC 3.6.1.47.
PR   PROSITE; PDOC00859;
//
ID   3.6.5.3
DE   Protein-synthesizing GTPase.
AN   Elongation factor (EF).
AN   Initiation factor (IF).
AN   Peptide-release factor (RF).
AN   Peptide-release or termination factor.
CA   GTP + H(2)O = GDP + phosphate.
CC   -!- This enzyme comprises a family of proteins involved in prokaryotic as
CC       well as eukaryotic protein synthesis.
CC   -!- In the initiation factor complex, it is IF-2b (98 kDa) that binds GTP
CC       and subsequently hydrolyzes it in prokaryotes.
CC   -!- In eukaryotes, it is eIF-2 (150 kDa) that binds GTP.
CC   -!- In the elongation phase, the GTP-hydrolyzing proteins are the EF-Tu
CC       polypeptide of the prokaryotic transfer factor (43 kDa),
CC       the eukaryotic elongation factor EF-1-alpha (53 kDa), the prokaryotic
CC       EF-G (77 kDa), the eukaryotic EF-2 (70-110 kDa) and the signal
CC       recognition particle that play a role in endoplasmic reticulum
CC       protein synthesis (325 kDa).
CC   -!- EF-Tu and EF-1-alpha catalyze binding of aminoacyl-tRNA to the
CC       ribosomal A-site, while EF-G and EF-2 catalyze the translocation of
CC       peptidyl-tRNA from the A-site to the P-site.
CC   -!- GTPase activity is also involved in polypeptide release from the
CC       ribosome with the aid of the pRFs and eRFs.
CC   -!- Formerly EC 3.6.1.48.
PR   PROSITE; PDOC00273;
PR   PROSITE; PDOC00905;
PR   PROSITE; PDOC00970;
//
ID   3.6.5.4
DE   Signal-recognition-particle GTPase.
CA   GTP + H(2)O = GDP + phosphate.
CC   -!- Activity is associated with the signal-recognition particle (a
CC       protein- and RNA-containing structure involved in endoplasmic-
CC       reticulum-associated protein synthesis).
CC   -!- Formerly EC 3.6.1.49.
PR   PROSITE; PDOC00272;
//
ID   3.6.5.5
DE   Dynamin GTPase.
CA   GTP + H(2)O = GDP + phosphate.
CC   -!- An enzyme with a molecular mass of about 100 kDa that is involved in
CC       endocytosis and is instrumental in pinching off membrane vesicles.
CC   -!- Formerly EC 3.6.1.50.
PR   PROSITE; PDOC00362;
DR   Q84N64, ARC5_ARATH ;  Q55F94, DLPA_DICDI ;  Q54MH8, DLPB_DICDI ;
DR   Q55AX0, DLPC_DICDI ;  Q2KIA5, DNM1L_BOVIN;  Q7SXN5, DNM1L_DANRE;
DR   O00429, DNM1L_HUMAN;  Q8K1M6, DNM1L_MOUSE;  O35303, DNM1L_RAT  ;
DR   P54861, DNM1_YEAST ;  Q9SE83, DRP2A_ARATH;  Q9LQ55, DRP2B_ARATH;
DR   Q08DF4, DYN1_BOVIN ;  P39055, DYN1_CAEEL ;  Q05193, DYN1_HUMAN ;
DR   P39053, DYN1_MOUSE ;  P21575, DYN1_RAT   ;  A6H7I5, DYN2_BOVIN ;
DR   P50570, DYN2_HUMAN ;  P39054, DYN2_MOUSE ;  P39052, DYN2_RAT   ;
DR   Q9UQ16, DYN3_HUMAN ;  Q8BZ98, DYN3_MOUSE ;  Q08877, DYN3_RAT   ;
DR   P27619, DYN_DROME  ;
//
ID   3.6.5.6
DE   Tubulin GTPase.
CA   GTP + H(2)O = GDP + phosphate.
CC   -!- An intrinsic activity of alpha-tubulin involved in tubulin folding,
CC       division plane formation in prokaryotic cells and others.
CC   -!- Formerly EC 3.6.1.51.
PR   PROSITE; PDOC00199;
//
ID   3.6.5.n1
DE   Elongation factor 4.
CA   GTP + H(2)O = GDP + phosphate.
CC   -!- The enzyme is required for accurate and efficient protein synthesis
CC       under certain stress conditions.
CC   -!- May act as a fidelity factor of the translation reaction,
CC       by catalyzing a one-codon backward translocation of tRNAs on
CC       improperly translocated ribosomes.
CC   -!- Back-translocation proceeds from a post-translocation (POST) complex
CC       to a pre-translocation (PRE) complex, thus giving elongation factor G
CC       a second chance to translocate the tRNAs correctly.
CC   -!- Binds to ribosomes in a GTP-dependent manner.
PR   PROSITE; PDOC00273;
DR   Q88VN0, LEPA1_LACPL;  Q7UX15, LEPA1_RHOBA;  Q88T65, LEPA2_LACPL;
DR   Q7UE01, LEPA2_RHOBA;  B0C9R9, LEPA_ACAM1 ;  A1TLE7, LEPA_ACIAC ;
DR   Q6F9B9, LEPA_ACIAD ;  B7GYS7, LEPA_ACIB3 ;  B7I580, LEPA_ACIB5 ;
DR   B2HWQ2, LEPA_ACIBC ;  Q1IV51, LEPA_ACIBL ;  B0VTM2, LEPA_ACIBS ;
DR   A3M7P5, LEPA_ACIBT ;  B0VCT7, LEPA_ACIBY ;  C1F2I3, LEPA_ACIC5 ;
DR   A5FY07, LEPA_ACICJ ;  B9MDP9, LEPA_ACIET ;  B7J9J8, LEPA_ACIF2 ;
DR   B5EQB5, LEPA_ACIF5 ;  A1WAW8, LEPA_ACISJ ;  A6VLV6, LEPA_ACTSZ ;
DR   A0KGF0, LEPA_AERHH ;  A4SRD4, LEPA_AERS4 ;  Q8UIQ2, LEPA_AGRT5 ;
DR   Q0VP16, LEPA_ALCBS ;  Q0A8Z4, LEPA_ALHEH ;  B6EKN1, LEPA_ALISL ;
DR   A6TSM4, LEPA_ALKMQ ;  A8MFA6, LEPA_ALKOO ;  B4RVA8, LEPA_ALTMD ;
DR   B3ESU2, LEPA_AMOA5 ;  B8JAF3, LEPA_ANAD2 ;  Q2IIA6, LEPA_ANADE ;
DR   A7HCF3, LEPA_ANADF ;  B9KIE5, LEPA_ANAMF ;  Q5PAX8, LEPA_ANAMM ;
DR   Q2GJV7, LEPA_ANAPZ ;  B4UDQ7, LEPA_ANASK ;  B9MJZ5, LEPA_ANATD ;
DR   Q3MG20, LEPA_ANAVT ;  B7GKC4, LEPA_ANOFW ;  O67618, LEPA_AQUAE ;
DR   Q5P089, LEPA_AROAE ;  A1R6W8, LEPA_ARTAT ;  B8H8S3, LEPA_ARTCA ;
DR   A0JX50, LEPA_ARTS2 ;  Q2NJE6, LEPA_AYWBP ;  A1K601, LEPA_AZOSB ;
DR   C1DQS0, LEPA_AZOVD ;  A7Z6W5, LEPA_BACA2 ;  C3P8M5, LEPA_BACAA ;
DR   C3L5S2, LEPA_BACAC ;  A0RIT7, LEPA_BACAH ;  Q81LR7, LEPA_BACAN ;
DR   B7JNV1, LEPA_BACC0 ;  Q730L6, LEPA_BACC1 ;  B7IYH2, LEPA_BACC2 ;
DR   C1ESL3, LEPA_BACC3 ;  B7HCU5, LEPA_BACC4 ;  B7HPL8, LEPA_BACC7 ;
DR   A7GT14, LEPA_BACCN ;  B9IY86, LEPA_BACCQ ;  Q818E4, LEPA_BACCR ;
DR   Q634M2, LEPA_BACCZ ;  Q5LC85, LEPA_BACFN ;  Q64T74, LEPA_BACFR ;
DR   Q9KD76, LEPA_BACHD ;  Q6HDK2, LEPA_BACHK ;  Q65H50, LEPA_BACLD ;
DR   A8FFD6, LEPA_BACP2 ;  Q5WHG5, LEPA_BACSK ;  P37949, LEPA_BACSU ;
DR   Q8AA33, LEPA_BACTN ;  A6L744, LEPA_BACV8 ;  A9VHU6, LEPA_BACWK ;
DR   Q6G550, LEPA_BARHE ;  Q6G1F5, LEPA_BARQU ;  Q1LTI1, LEPA_BAUCH ;
DR   P60930, LEPA_BDEBA ;  B8DUL6, LEPA_BIFA0 ;  B3DSA9, LEPA_BIFLD ;
DR   Q8G603, LEPA_BIFLO ;  B7GRY7, LEPA_BIFLS ;  Q7VRQ8, LEPA_BLOFL ;
DR   Q492C9, LEPA_BLOPB ;  Q2KWY3, LEPA_BORA1 ;  Q0SP76, LEPA_BORAP ;
DR   Q7WD30, LEPA_BORBR ;  O51115, LEPA_BORBU ;  Q662S4, LEPA_BORGA ;
DR   Q7W5J4, LEPA_BORPA ;  A9III9, LEPA_BORPD ;  P56865, LEPA_BORPE ;
DR   Q89BJ8, LEPA_BRAJA ;  B2SC25, LEPA_BRUA1 ;  Q2YJP8, LEPA_BRUA2 ;
DR   Q576S5, LEPA_BRUAB ;  A9MCW5, LEPA_BRUC2 ;  C0RMH8, LEPA_BRUMB ;
DR   Q8YDB8, LEPA_BRUME ;  A5VVU4, LEPA_BRUO2 ;  A9WW49, LEPA_BRUSI ;
DR   Q8FV17, LEPA_BRUSU ;  B8D953, LEPA_BUCA5 ;  P57348, LEPA_BUCAI ;
DR   Q8K9Q9, LEPA_BUCAP ;  B8D7F7, LEPA_BUCAT ;  Q89AM5, LEPA_BUCBP ;
DR   Q057R2, LEPA_BUCCC ;  B1YVM2, LEPA_BURA4 ;  Q1BXU3, LEPA_BURCA ;
DR   B1JYB1, LEPA_BURCC ;  A0K5V7, LEPA_BURCH ;  Q0BH06, LEPA_BURCM ;
DR   A9ADE0, LEPA_BURM1 ;  A3MM44, LEPA_BURM7 ;  A2S9Z3, LEPA_BURM9 ;
DR   Q62LT1, LEPA_BURMA ;  A1V6B9, LEPA_BURMS ;  A3NXL8, LEPA_BURP0 ;
DR   Q3JQ75, LEPA_BURP1 ;  A3NBT1, LEPA_BURP6 ;  B2JFK0, LEPA_BURP8 ;
DR   B2SZV7, LEPA_BURPP ;  Q63S94, LEPA_BURPS ;  Q39I75, LEPA_BURS3 ;
DR   Q2SXT6, LEPA_BURTA ;  A4JCQ9, LEPA_BURVG ;  Q13VM6, LEPA_BURXL ;
DR   A4XKA0, LEPA_CALS8 ;  A7ZCJ3, LEPA_CAMC1 ;  A7GZW3, LEPA_CAMC5 ;
DR   A0RQX4, LEPA_CAMFF ;  A7I1F0, LEPA_CAMHC ;  A8FM79, LEPA_CAMJ8 ;
DR   A7H311, LEPA_CAMJD ;  Q9PNR1, LEPA_CAMJE ;  A1W018, LEPA_CAMJJ ;
DR   Q5HU70, LEPA_CAMJR ;  B9KD01, LEPA_CAMLR ;  Q3AF13, LEPA_CARHZ ;
DR   B8H2Z7, LEPA_CAUCN ;  Q9A9F4, LEPA_CAUCR ;  B3PLG4, LEPA_CELJU ;
DR   Q5L659, LEPA_CHLAB ;  Q3ATB2, LEPA_CHLCH ;  Q823H7, LEPA_CHLCV ;
DR   Q254E1, LEPA_CHLFF ;  B3EE17, LEPA_CHLL2 ;  Q9PKX6, LEPA_CHLMU ;
DR   B3QPU3, LEPA_CHLP8 ;  B3EPG7, LEPA_CHLPB ;  A1BHJ8, LEPA_CHLPD ;
DR   Q9Z8I4, LEPA_CHLPN ;  B0B9H2, LEPA_CHLT2 ;  Q3KMV7, LEPA_CHLTA ;
DR   B0BB51, LEPA_CHLTB ;  Q8KCH0, LEPA_CHLTE ;  O84067, LEPA_CHLTR ;
DR   Q1QX26, LEPA_CHRSD ;  Q7NWC7, LEPA_CHRVO ;  A8AD16, LEPA_CITK8 ;
DR   A5CR97, LEPA_CLAM3 ;  B0RCT0, LEPA_CLAMS ;  Q97JJ6, LEPA_CLOAB ;
DR   A7FXL9, LEPA_CLOB1 ;  C3L3H1, LEPA_CLOB6 ;  A5I644, LEPA_CLOBH ;
DR   C1FVU4, LEPA_CLOBJ ;  B1ILM7, LEPA_CLOBK ;  A7GHI0, LEPA_CLOBL ;
DR   B1KZP1, LEPA_CLOBM ;  B8I3E6, LEPA_CLOCE ;  Q182F4, LEPA_CLOD6 ;
DR   A5N6L8, LEPA_CLOK5 ;  A0Q1R8, LEPA_CLONN ;  Q0TNS2, LEPA_CLOP1 ;
DR   Q8XIS6, LEPA_CLOPE ;  A9KKU4, LEPA_CLOPH ;  Q0SRD8, LEPA_CLOPS ;
DR   Q892Q6, LEPA_CLOTE ;  A3DF29, LEPA_CLOTH ;  Q47WP3, LEPA_COLP3 ;
DR   C3PHY1, LEPA_CORA7 ;  P60931, LEPA_CORDI ;  Q8FNA3, LEPA_COREF ;
DR   Q8NN68, LEPA_CORGL ;  Q4JWS1, LEPA_CORJK ;  B1VGK6, LEPA_CORU7 ;
DR   A9KF98, LEPA_COXBN ;  A9N944, LEPA_COXBR ;  Q83BK3, LEPA_COXBU ;
DR   Q0K8N0, LEPA_CUPNH ;  Q46Z15, LEPA_CUPPJ ;  B3R202, LEPA_CUPTR ;
DR   B1WWD8, LEPA_CYAA5 ;  B8HLK8, LEPA_CYAP4 ;  B7KJX0, LEPA_CYAP7 ;
DR   B7K3Z7, LEPA_CYAP8 ;  Q11UD0, LEPA_CYTH3 ;  Q47EG0, LEPA_DECAR ;
DR   Q3Z864, LEPA_DEHE1 ;  A5FR18, LEPA_DEHSB ;  Q3ZXK4, LEPA_DEHSC ;
DR   Q1IXW5, LEPA_DEIGD ;  Q9RV84, LEPA_DEIRA ;  A9BNJ8, LEPA_DELAS ;
DR   C6BST2, LEPA_DESAD ;  B1I6E0, LEPA_DESAP ;  B8J444, LEPA_DESDA ;
DR   Q30XI4, LEPA_DESDG ;  B8FUP2, LEPA_DESHD ;  Q24SR6, LEPA_DESHY ;
DR   A9A0N0, LEPA_DESOH ;  Q6AL53, LEPA_DESPS ;  A4J7F8, LEPA_DESRM ;
DR   Q72E76, LEPA_DESVH ;  B8DIZ5, LEPA_DESVM ;  A8LR11, LEPA_DINSH ;
DR   A7ZQ13, LEPA_ECO24 ;  B7UH09, LEPA_ECO27 ;  B7MIQ4, LEPA_ECO45 ;
DR   B7LDG2, LEPA_ECO55 ;  P60787, LEPA_ECO57 ;  B5Z143, LEPA_ECO5E ;
DR   B7NRM2, LEPA_ECO7I ;  B7MYK1, LEPA_ECO81 ;  B7M8I2, LEPA_ECO8A ;
DR   C4ZYJ2, LEPA_ECOBW ;  B1XB43, LEPA_ECODH ;  A8A379, LEPA_ECOHS ;
DR   A1AE99, LEPA_ECOK1 ;  Q0TER9, LEPA_ECOL5 ;  P60786, LEPA_ECOL6 ;
DR   B1IVQ8, LEPA_ECOLC ;  P60785, LEPA_ECOLI ;  B7N6F7, LEPA_ECOLU ;
DR   B6I5E3, LEPA_ECOSE ;  B1LP82, LEPA_ECOSM ;  Q1R8G3, LEPA_ECOUT ;
DR   C5BAI0, LEPA_EDWI9 ;  Q3YSC2, LEPA_EHRCJ ;  Q2GGA6, LEPA_EHRCR ;
DR   Q5FHQ1, LEPA_EHRRG ;  Q5HBH4, LEPA_EHRRW ;  A4WDE0, LEPA_ENT38 ;
DR   Q831Z0, LEPA_ENTFA ;  A7MH13, LEPA_ENTS8 ;  Q6D217, LEPA_ERWCT ;
DR   B2VI44, LEPA_ERWT9 ;  Q2N9U6, LEPA_ERYLH ;  B7LUZ5, LEPA_ESCF3 ;
DR   C4Z541, LEPA_EUBE2 ;  C4Z9E3, LEPA_EUBR3 ;  B1YKS5, LEPA_EXIS2 ;
DR   C4L433, LEPA_EXISA ;  B0S1G2, LEPA_FINM2 ;  A5FLU8, LEPA_FLAJ1 ;
DR   A6H1S4, LEPA_FLAPJ ;  Q0RP81, LEPA_FRAAA ;  B0TW33, LEPA_FRAP2 ;
DR   Q2JDK2, LEPA_FRASC ;  Q14FW1, LEPA_FRAT1 ;  A7N9A4, LEPA_FRATF ;
DR   Q2A5X6, LEPA_FRATH ;  B2SEJ6, LEPA_FRATM ;  A0Q453, LEPA_FRATN ;
DR   Q0BP65, LEPA_FRATO ;  Q5NEF8, LEPA_FRATT ;  A4J080, LEPA_FRATW ;
DR   Q8RFD1, LEPA_FUSNN ;  B5EB36, LEPA_GEOBB ;  Q5KWZ3, LEPA_GEOKA ;
DR   B3E9R0, LEPA_GEOLS ;  Q39US7, LEPA_GEOMG ;  B9M4U5, LEPA_GEOSF ;
DR   P60789, LEPA_GEOSL ;  C6DZ67, LEPA_GEOSM ;  A4IR35, LEPA_GEOTN ;
DR   A5G4G3, LEPA_GEOUR ;  Q7NGX4, LEPA_GLOVI ;  A9HG78, LEPA_GLUDA ;
DR   Q5FUC2, LEPA_GLUOX ;  Q0BRZ7, LEPA_GRABC ;  A0M6M2, LEPA_GRAFK ;
DR   Q7VL73, LEPA_HAEDU ;  Q4QPM8, LEPA_HAEI8 ;  A5UBC2, LEPA_HAEIE ;
DR   A5UFI9, LEPA_HAEIG ;  P43729, LEPA_HAEIN ;  Q0I4Z1, LEPA_HAES1 ;
DR   B0USR9, LEPA_HAES2 ;  Q2SL35, LEPA_HAHCH ;  C4K3Z1, LEPA_HAMD5 ;
DR   Q17X87, LEPA_HELAH ;  Q7VJZ1, LEPA_HELHP ;  B0TAD2, LEPA_HELMI ;
DR   B6JKS8, LEPA_HELP2 ;  B5ZAB8, LEPA_HELPG ;  Q1CUF5, LEPA_HELPH ;
DR   Q9ZM93, LEPA_HELPJ ;  B2USI5, LEPA_HELPS ;  O25122, LEPA_HELPY ;
DR   A4G6S1, LEPA_HERAR ;  B4U6M2, LEPA_HYDS0 ;  Q0C5X0, LEPA_HYPNA ;
DR   Q5R104, LEPA_IDILO ;  A6SXR0, LEPA_JANMA ;  Q28LR4, LEPA_JANSC ;
DR   A6WDJ3, LEPA_KINRD ;  B5XNG8, LEPA_KLEP3 ;  A6TCI3, LEPA_KLEP7 ;
DR   B2GHU9, LEPA_KOCRD ;  Q5FJP6, LEPA_LACAC ;  Q03QU8, LEPA_LACBA ;
DR   Q038N6, LEPA_LACC3 ;  B3WEQ5, LEPA_LACCB ;  Q1G9R4, LEPA_LACDA ;
DR   Q049W8, LEPA_LACDB ;  B2GBR9, LEPA_LACF3 ;  Q044A7, LEPA_LACGA ;
DR   A8YVQ1, LEPA_LACH4 ;  P60790, LEPA_LACJO ;  Q9CGI8, LEPA_LACLA ;
DR   A2RL76, LEPA_LACLM ;  Q02Z80, LEPA_LACLS ;  A5VJE9, LEPA_LACRD ;
DR   B2G6W5, LEPA_LACRJ ;  Q1WUE6, LEPA_LACS1 ;  Q38W39, LEPA_LACSS ;
DR   C1D7L2, LEPA_LARHH ;  Q1MQF3, LEPA_LAWIP ;  Q5X443, LEPA_LEGPA ;
DR   A5ID24, LEPA_LEGPC ;  Q5ZUD2, LEPA_LEGPH ;  Q5WVI1, LEPA_LEGPL ;
DR   Q6AEB5, LEPA_LEIXX ;  B0S8S7, LEPA_LEPBA ;  Q04SN9, LEPA_LEPBJ ;
DR   Q050R3, LEPA_LEPBL ;  B0SRL4, LEPA_LEPBP ;  B1XZN0, LEPA_LEPCP ;
DR   Q72QU8, LEPA_LEPIC ;  Q8F500, LEPA_LEPIN ;  Q92BN4, LEPA_LISIN ;
DR   C1KVC6, LEPA_LISMC ;  Q71ZJ1, LEPA_LISMF ;  B8DE32, LEPA_LISMH ;
DR   Q8Y742, LEPA_LISMO ;  A0AIS8, LEPA_LISW6 ;  B9E6X5, LEPA_MACCJ ;
DR   Q2W0F9, LEPA_MAGSA ;  A0L631, LEPA_MAGSM ;  Q65VN2, LEPA_MANSM ;
DR   A1U2V8, LEPA_MARAV ;  Q0ATE3, LEPA_MARMM ;  Q6F0Z2, LEPA_MESFL ;
DR   Q11AY3, LEPA_MESSB ;  B7KR78, LEPA_METC4 ;  Q608M4, LEPA_METCA ;
DR   Q1H2L5, LEPA_METFK ;  B8IMT0, LEPA_METNO ;  B1ZC10, LEPA_METPB ;
DR   A2SDH0, LEPA_METPP ;  B0UFE0, LEPA_METS4 ;  B8ENL1, LEPA_METSB ;
DR   B0JQT7, LEPA_MICAN ;  C5CCD4, LEPA_MICLC ;  Q2RKX8, LEPA_MOOTA ;
DR   B3PLU0, LEPA_MYCA5 ;  A5IYS0, LEPA_MYCAP ;  P65270, LEPA_MYCBO ;
DR   A1KL96, LEPA_MYCBP ;  C1AQW9, LEPA_MYCBT ;  Q2SSF7, LEPA_MYCCT ;
DR   Q8GCP5, LEPA_MYCFE ;  Q7NAT2, LEPA_MYCGA ;  P47384, LEPA_MYCGE ;
DR   Q9ZHZ8, LEPA_MYCH2 ;  Q4A8T9, LEPA_MYCH7 ;  Q4AAQ8, LEPA_MYCHJ ;
DR   B8ZUS2, LEPA_MYCLB ;  P53530, LEPA_MYCLE ;  Q6KHP1, LEPA_MYCMO ;
DR   Q6MTR6, LEPA_MYCMS ;  P60791, LEPA_MYCPA ;  Q8EWZ9, LEPA_MYCPE ;
DR   P75498, LEPA_MYCPN ;  Q98QW3, LEPA_MYCPU ;  Q4A5S3, LEPA_MYCS5 ;
DR   A3Q2A6, LEPA_MYCSJ ;  A1UIU2, LEPA_MYCSK ;  Q1B684, LEPA_MYCSS ;
DR   A5U598, LEPA_MYCTA ;  P65269, LEPA_MYCTU ;  Q1D6M1, LEPA_MYXXD ;
DR   Q5F9P9, LEPA_NEIG1 ;  B4RK41, LEPA_NEIG2 ;  A9M3J8, LEPA_NEIM0 ;
DR   Q9JV65, LEPA_NEIMA ;  Q9K055, LEPA_NEIMB ;  A1KT27, LEPA_NEIMF ;
DR   Q2GD00, LEPA_NEOSM ;  Q0AF67, LEPA_NITEC ;  Q820H8, LEPA_NITEU ;
DR   Q1QR19, LEPA_NITHX ;  Q2Y873, LEPA_NITMU ;  Q3J8D2, LEPA_NITOC ;
DR   A6Q241, LEPA_NITSB ;  Q3SVT1, LEPA_NITWN ;  Q5YZZ7, LEPA_NOCFA ;
DR   B2J0M4, LEPA_NOSP7 ;  Q8YU48, LEPA_NOSS1 ;  Q2G550, LEPA_NOVAD ;
DR   Q8CXD0, LEPA_OCEIH ;  A6WYK4, LEPA_OCHA4 ;  B6JJT7, LEPA_OLICO ;
DR   P60792, LEPA_ONYPE ;  A5CE57, LEPA_ORITB ;  B3CRQ1, LEPA_ORITI ;
DR   A6LC18, LEPA_PARD8 ;  Q6MEF3, LEPA_PARUW ;  P57806, LEPA_PASMU ;
DR   C6DC02, LEPA_PECCP ;  Q3A445, LEPA_PELCD ;  Q3B2V1, LEPA_PELLD ;
DR   B4SBG4, LEPA_PELPB ;  A1ARG8, LEPA_PELPD ;  A5D3X6, LEPA_PELTS ;
DR   Q4FNH3, LEPA_PELUB ;  Q7N1X3, LEPA_PHOLL ;  Q6LMS0, LEPA_PHOPR ;
DR   B1V9C5, LEPA_PHYAS ;  B3QZT9, LEPA_PHYMT ;  A1VRT5, LEPA_POLNA ;
DR   B1XTL2, LEPA_POLNS ;  Q126K0, LEPA_POLSJ ;  A4SVW0, LEPA_POLSQ ;
DR   B2RKK1, LEPA_PORG3 ;  Q7MV56, LEPA_PORGI ;  B4S9B7, LEPA_PROA2 ;
DR   Q6A9B2, LEPA_PROAC ;  A3PBD8, LEPA_PROM0 ;  A2C0M8, LEPA_PROM1 ;
DR   A8G3D2, LEPA_PROM2 ;  A2CBG9, LEPA_PROM3 ;  A9BE39, LEPA_PROM4 ;
DR   A2BV79, LEPA_PROM5 ;  Q31CB8, LEPA_PROM9 ;  Q7VDF7, LEPA_PROMA ;
DR   B4F049, LEPA_PROMH ;  Q7V8S4, LEPA_PROMM ;  Q7V2Q1, LEPA_PROMP ;
DR   A2BPP8, LEPA_PROMS ;  Q46GZ6, LEPA_PROMT ;  A4SFN5, LEPA_PROVI ;
DR   Q48EV0, LEPA_PSE14 ;  Q15R31, LEPA_PSEA6 ;  A6VAK9, LEPA_PSEA7 ;
DR   B7UYX5, LEPA_PSEA8 ;  Q02HR9, LEPA_PSEAB ;  Q9I5G8, LEPA_PSEAE ;
DR   Q1I5V6, LEPA_PSEE4 ;  Q4KHT3, LEPA_PSEF5 ;  P26843, LEPA_PSEFL ;
DR   C3K6G8, LEPA_PSEFS ;  Q3IDL4, LEPA_PSEHT ;  A4XSC1, LEPA_PSEMY ;
DR   A5W8F4, LEPA_PSEP1 ;  Q3KHM1, LEPA_PSEPF ;  B0KV29, LEPA_PSEPG ;
DR   Q88MY7, LEPA_PSEPK ;  B1J4D8, LEPA_PSEPW ;  Q87XF8, LEPA_PSESM ;
DR   Q4ZPD8, LEPA_PSEU2 ;  A4VIX2, LEPA_PSEU5 ;  Q4FUV9, LEPA_PSYA2 ;
DR   Q1QDV6, LEPA_PSYCK ;  A1SSM6, LEPA_PSYIN ;  A5WCD6, LEPA_PSYWF ;
DR   Q1LKM8, LEPA_RALME ;  B2U978, LEPA_RALPJ ;  Q8Y0I4, LEPA_RALSO ;
DR   B3PYC6, LEPA_RHIE6 ;  Q2KDL5, LEPA_RHIEC ;  Q1MMQ8, LEPA_RHIL3 ;
DR   Q98DV1, LEPA_RHILO ;  B5ZXQ5, LEPA_RHILW ;  Q92SU3, LEPA_RHIME ;
DR   B6IUG3, LEPA_RHOCS ;  Q21XN4, LEPA_RHOFD ;  C1AUN7, LEPA_RHOOB ;
DR   Q2J2Y0, LEPA_RHOP2 ;  Q07TF1, LEPA_RHOP5 ;  P60793, LEPA_RHOPA ;
DR   Q21BS0, LEPA_RHOPB ;  Q13E78, LEPA_RHOPS ;  B3Q991, LEPA_RHOPT ;
DR   Q2RNY6, LEPA_RHORT ;  A3PHQ9, LEPA_RHOS1 ;  Q3J4P0, LEPA_RHOS4 ;
DR   A4WX88, LEPA_RHOS5 ;  B9KNH9, LEPA_RHOSK ;  Q0SH84, LEPA_RHOSR ;
DR   C3PMX3, LEPA_RICAE ;  A8GMT1, LEPA_RICAH ;  A8GW16, LEPA_RICB8 ;
DR   A8EY28, LEPA_RICCK ;  Q92IQ1, LEPA_RICCN ;  Q4UKS2, LEPA_RICFE ;
DR   Q9ZDQ1, LEPA_RICPR ;  C4K153, LEPA_RICPU ;  B0BWV5, LEPA_RICRO ;
DR   A8GRF6, LEPA_RICRS ;  Q68X95, LEPA_RICTY ;  Q16BA3, LEPA_ROSDO ;
DR   Q1AVV0, LEPA_RUBXD ;  A1AWP9, LEPA_RUTMC ;  Q21IH3, LEPA_SACD2 ;
DR   B5F1G3, LEPA_SALA4 ;  A9MGX5, LEPA_SALAR ;  Q57LC8, LEPA_SALCH ;
DR   B5FRC7, LEPA_SALDC ;  B5QTV0, LEPA_SALEP ;  B5RD51, LEPA_SALG2 ;
DR   B4TE17, LEPA_SALHS ;  B4T1G0, LEPA_SALNS ;  Q5PNC0, LEPA_SALPA ;
DR   C0PYG5, LEPA_SALPC ;  B5BAS8, LEPA_SALPK ;  B4TS16, LEPA_SALSV ;
DR   P0A1W5, LEPA_SALTI ;  P0A1W4, LEPA_SALTY ;  A8GI27, LEPA_SERP5 ;
DR   A1S3X9, LEPA_SHEAM ;  B8EBQ4, LEPA_SHEB2 ;  A3D1V4, LEPA_SHEB5 ;
DR   A6WKQ5, LEPA_SHEB8 ;  A9L5N4, LEPA_SHEB9 ;  Q12KH9, LEPA_SHEDO ;
DR   Q07YZ4, LEPA_SHEFN ;  B0TIV5, LEPA_SHEHH ;  A3QBS5, LEPA_SHELP ;
DR   Q8EH83, LEPA_SHEON ;  A8H1C5, LEPA_SHEPA ;  A4Y4K2, LEPA_SHEPC ;
DR   B8CQJ7, LEPA_SHEPW ;  A0KZN4, LEPA_SHESA ;  A8FSD4, LEPA_SHESH ;
DR   Q0HG96, LEPA_SHESM ;  Q0HSI9, LEPA_SHESR ;  A1RMC9, LEPA_SHESW ;
DR   B1KI55, LEPA_SHEWM ;  B2TYI0, LEPA_SHIB3 ;  Q31XR8, LEPA_SHIBS ;
DR   Q32CV2, LEPA_SHIDS ;  Q0T1T6, LEPA_SHIF8 ;  P60788, LEPA_SHIFL ;
DR   Q3YYU7, LEPA_SHISS ;  Q5LUS0, LEPA_SILPO ;  Q1GIV5, LEPA_SILST ;
DR   Q2NS11, LEPA_SODGM ;  Q01SV7, LEPA_SOLUE ;  A9GWZ4, LEPA_SORC5 ;
DR   Q1GRH5, LEPA_SPHAL ;  A5VB59, LEPA_SPHWW ;  A7X2Y7, LEPA_STAA1 ;
DR   A6U257, LEPA_STAA2 ;  Q2FGD9, LEPA_STAA3 ;  Q2FXY7, LEPA_STAA8 ;
DR   A5ITB2, LEPA_STAA9 ;  Q2YT42, LEPA_STAAB ;  Q5HFH6, LEPA_STAAC ;
DR   A6QHC7, LEPA_STAAE ;  P65271, LEPA_STAAM ;  P65272, LEPA_STAAN ;
DR   Q6GGB6, LEPA_STAAR ;  Q6G8Y3, LEPA_STAAS ;  A8Z4C4, LEPA_STAAT ;
DR   Q8NWA7, LEPA_STAAW ;  B9DNK4, LEPA_STACT ;  Q5HNW2, LEPA_STAEQ ;
DR   Q8CP13, LEPA_STAES ;  Q4L6T4, LEPA_STAHJ ;  Q49Y26, LEPA_STAS1 ;
DR   Q3K1F9, LEPA_STRA1 ;  P65273, LEPA_STRA3 ;  P65274, LEPA_STRA5 ;
DR   Q82BZ3, LEPA_STRAW ;  Q9RDC9, LEPA_STRCO ;  C0M8H9, LEPA_STRE4 ;
DR   B4U3G9, LEPA_STREM ;  A8AWG3, LEPA_STRGC ;  B1VY28, LEPA_STRGG ;
DR   B4SRL3, LEPA_STRM5 ;  B2FQC4, LEPA_STRMK ;  Q8DTF3, LEPA_STRMU ;
DR   Q99ZV8, LEPA_STRP1 ;  Q04KB7, LEPA_STRP2 ;  P0DC22, LEPA_STRP3 ;
DR   B5E4T8, LEPA_STRP4 ;  Q5XCD2, LEPA_STRP6 ;  C1C7G9, LEPA_STRP7 ;
DR   Q8P173, LEPA_STRP8 ;  Q1JC06, LEPA_STRPB ;  Q1JLY8, LEPA_STRPC ;
DR   Q1JH37, LEPA_STRPD ;  Q1J6V6, LEPA_STRPF ;  B1IC02, LEPA_STRPI ;
DR   B8ZQ69, LEPA_STRPJ ;  Q48TU0, LEPA_STRPM ;  Q97QK5, LEPA_STRPN ;
DR   P0DC23, LEPA_STRPQ ;  B5XLC6, LEPA_STRPZ ;  Q8DPN5, LEPA_STRR6 ;
DR   A4W0W0, LEPA_STRS2 ;  C0MDV7, LEPA_STRS7 ;  A4VUL8, LEPA_STRSY ;
DR   Q5M008, LEPA_STRT1 ;  Q5M4M2, LEPA_STRT2 ;  Q03KW7, LEPA_STRTD ;
DR   B9DSE0, LEPA_STRU0 ;  C1CEG3, LEPA_STRZJ ;  C1CKU6, LEPA_STRZP ;
DR   C1CR98, LEPA_STRZT ;  Q30Q17, LEPA_SULDN ;  Q67S76, LEPA_SYMTH ;
DR   Q2LTN3, LEPA_SYNAS ;  Q31R08, LEPA_SYNE7 ;  A0LI00, LEPA_SYNFM ;
DR   Q2JWR1, LEPA_SYNJA ;  Q2JQ51, LEPA_SYNJB ;  B1XK44, LEPA_SYNP2 ;
DR   Q5N390, LEPA_SYNP6 ;  A5GMR2, LEPA_SYNPW ;  Q7U5L9, LEPA_SYNPX ;
DR   A5GRE6, LEPA_SYNR3 ;  Q0ICF2, LEPA_SYNS3 ;  Q3AWX3, LEPA_SYNS9 ;
DR   Q3ALG5, LEPA_SYNSC ;  Q0AWL9, LEPA_SYNWW ;  P74751, LEPA_SYNY3 ;
DR   C5BRN3, LEPA_TERTT ;  Q8DM20, LEPA_THEEB ;  Q47RQ0, LEPA_THEFY ;
DR   Q9X1V8, LEPA_THEMA ;  B0KA85, LEPA_THEP3 ;  B0K3Y4, LEPA_THEPX ;
DR   Q72KV2, LEPA_THET2 ;  Q5SKA7, LEPA_THET8 ;  Q8RB72, LEPA_THETN ;
DR   Q31HP5, LEPA_THICR ;  Q3SH47, LEPA_THIDA ;  C4LBZ6, LEPA_TOLAT ;
DR   P60794, LEPA_TREDE ;  O83523, LEPA_TREPA ;  B2S3A4, LEPA_TREPS ;
DR   Q112D2, LEPA_TRIEI ;  Q83NI1, LEPA_TROW8 ;  Q83MZ5, LEPA_TROWT ;
DR   B1AIW2, LEPA_UREP2 ;  Q9PQG7, LEPA_UREPA ;  B5ZBD4, LEPA_UREU1 ;
DR   C5CSF2, LEPA_VARPS ;  A1WMW4, LEPA_VEREI ;  A5CWJ4, LEPA_VESOH ;
DR   A5F5G3, LEPA_VIBC3 ;  Q9KPB0, LEPA_VIBCH ;  C3LR06, LEPA_VIBCM ;
DR   Q5E312, LEPA_VIBF1 ;  B5FAH2, LEPA_VIBFM ;  A7MZB0, LEPA_VIBHB ;
DR   Q87LN7, LEPA_VIBPA ;  B7VK81, LEPA_VIBSL ;  Q8DC78, LEPA_VIBVU ;
DR   Q7MHN6, LEPA_VIBVY ;  Q8D307, LEPA_WIGBR ;  Q73HR8, LEPA_WOLPM ;
DR   B3CPV1, LEPA_WOLPP ;  Q7M8H5, LEPA_WOLSU ;  Q5GRW9, LEPA_WOLTR ;
DR   C0R5S3, LEPA_WOLWR ;  Q8PMV3, LEPA_XANAC ;  Q3BVV9, LEPA_XANC5 ;
DR   Q4USF4, LEPA_XANC8 ;  B0RX30, LEPA_XANCB ;  Q8PB55, LEPA_XANCP ;
DR   Q2P4M4, LEPA_XANOM ;  B2SRY0, LEPA_XANOP ;  Q5H1R5, LEPA_XANOR ;
DR   A7IEG8, LEPA_XANP2 ;  B2I601, LEPA_XYLF2 ;  Q9PBA1, LEPA_XYLFA ;
DR   B0U3D5, LEPA_XYLFM ;  Q87C09, LEPA_XYLFT ;  A1JKK1, LEPA_YERE8 ;
DR   A7FFT7, LEPA_YERP3 ;  Q1C557, LEPA_YERPA ;  B2KA49, LEPA_YERPB ;
DR   Q8ZD74, LEPA_YERPE ;  A9R400, LEPA_YERPG ;  Q1CKE6, LEPA_YERPN ;
DR   A4TKY0, LEPA_YERPP ;  Q667U9, LEPA_YERPS ;  B1JRC5, LEPA_YERPY ;
DR   Q5NLP5, LEPA_ZYMMO ;
//
ID   3.7.1.1
DE   Oxaloacetase.
AN   Oxalacetic hydrolase.
CA   Oxaloacetate + H(2)O = oxalate + acetate.
DR   Q05957, PDP_DIACA  ;
//
ID   3.7.1.2
DE   Fumarylacetoacetase.
AN   Beta-diketonase.
AN   Fumarylacetoacetate hydrolase.
CA   4-fumarylacetoacetate + H(2)O = acetoacetate + fumarate.
CC   -!- Also acts on other 3,5- and 2,4-dioxo acids.
DR   A5PKH3, FAAA_BOVIN ;  Q1ZXQ1, FAAA_DICDI ;  Q00770, FAAA_EMENI ;
DR   P16930, FAAA_HUMAN ;  P35505, FAAA_MOUSE ;  P25093, FAAA_RAT   ;
//
ID   3.7.1.3
DE   Kynureninase.
AN   L-kynurenine hydrolase.
CA   L-kynurenine + H(2)O = anthranilate + L-alanine.
CF   Pyridoxal 5'-phosphate.
CC   -!- Also acts on 3'-hydroxykynurenine and some other (3-arylcarbonyl)-
CC       alanines.
DR   A1C688, KYNU1_ASPCL;  B0XS72, KYNU1_ASPFC;  Q4X1D4, KYNU1_ASPFU;
DR   A2R7T0, KYNU1_ASPNC;  Q2U038, KYNU1_ASPOR;  Q0CPB0, KYNU1_ASPTN;
DR   Q2H9P7, KYNU1_CHAGB;  Q5B0H8, KYNU1_EMENI;  A1DGW4, KYNU1_NEOFI;
DR   Q7RXY2, KYNU1_NEUCR;  Q0UIN2, KYNU1_PHANO;  A1CHT0, KYNU2_ASPCL;
DR   B0Y6H2, KYNU2_ASPFC;  Q4WPN0, KYNU2_ASPFU;  A2QJI5, KYNU2_ASPNC;
DR   Q2UJE8, KYNU2_ASPOR;  Q0CZX6, KYNU2_ASPTN;  Q2H7G2, KYNU2_CHAGB;
DR   Q5BC73, KYNU2_EMENI;  A1CWY1, KYNU2_NEOFI;  Q7S332, KYNU2_NEUCR;
DR   Q0UZK0, KYNU2_PHANO;  Q1ITW5, KYNU_ACIBL ;  Q750P5, KYNU_ASHGO ;
DR   A0REX2, KYNU_BACAH ;  Q81PP8, KYNU_BACAN ;  Q736W3, KYNU_BACC1 ;
DR   A7GPY3, KYNU_BACCN ;  Q81CK0, KYNU_BACCR ;  Q63AJ0, KYNU_BACCZ ;
DR   Q6HHX7, KYNU_BACHK ;  Q5WKB5, KYNU_BACSK ;  A9VHP9, KYNU_BACWK ;
DR   A6RSP5, KYNU_BOTFB ;  A3MHE2, KYNU_BURM7 ;  A2S925, KYNU_BURM9 ;
DR   Q62M98, KYNU_BURMA ;  A1V194, KYNU_BURMS ;  A3NS56, KYNU_BURP0 ;
DR   Q3JVD7, KYNU_BURP1 ;  A3N6H3, KYNU_BURP6 ;  Q63WP4, KYNU_BURPS ;
DR   A8XKT0, KYNU_CAEBR ;  Q18026, KYNU_CAEEL ;  Q59QC4, KYNU_CANAL ;
DR   Q1DZA6, KYNU_COCIM ;  P0CO53, KYNU_CRYNB ;  P0CO52, KYNU_CRYNJ ;
DR   Q6BI19, KYNU_DEBHA ;  Q9RYH5, KYNU_DEIRA ;  Q54Q04, KYNU_DICDI ;
DR   B1YHD6, KYNU_EXIS2 ;  A5FMM4, KYNU_FLAJ1 ;  A6H1P7, KYNU_FLAPJ ;
DR   A4IT57, KYNU_GEOTN ;  A0M4Y1, KYNU_GRAFK ;  Q16719, KYNU_HUMAN ;
DR   A5DTF4, KYNU_LODEL ;  A4UBV5, KYNU_MAGO7 ;  A9V3C0, KYNU_MONBE ;
DR   Q9CXF0, KYNU_MOUSE ;  Q1DDU5, KYNU_MYXXD ;  A7SCH8, KYNU_NEMVE ;
DR   A5DM91, KYNU_PICGU ;  A3LQD7, KYNU_PICST ;  P83788, KYNU_PSEFL ;
DR   P70712, KYNU_RAT   ;  A4XAL2, KYNU_SALTO ;  Q5DGJ1, KYNU_SCHJA ;
DR   A7ESB8, KYNU_SCLS1 ;  B1KJM4, KYNU_SHEWM ;  B2FL97, KYNU_STRMK ;
DR   A7TR79, KYNU_VANPO ;  Q8PM33, KYNU_XANAC ;  Q3BV40, KYNU_XANC5 ;
DR   Q4UT93, KYNU_XANC8 ;  B0RUZ9, KYNU_XANCB ;  Q8PAD2, KYNU_XANCP ;
DR   Q2P317, KYNU_XANOM ;  B2SIT8, KYNU_XANOP ;  Q5H039, KYNU_XANOR ;
DR   Q6CDM0, KYNU_YARLI ;  Q05979, KYNU_YEAST ;
//
ID   3.7.1.4
DE   Phloretin hydrolase.
CA   Phloretin + H(2)O = phloretate + phloroglucinol.
CC   -!- Also hydrolyzes other C-acylated phenols related to phloretin.
//
ID   3.7.1.5
DE   Acylpyruvate hydrolase.
CA   A 3-acylpyruvate + H(2)O = a carboxylate + pyruvate.
CC   -!- Acts on formylpyruvate, 2,4-dioxopentanoate, 2,4-dioxohexanoate and
CC       2,4-dioxoheptanoate.
//
ID   3.7.1.6
DE   Acetylpyruvate hydrolase.
CA   Acetylpyruvate + H(2)O = acetate + pyruvate.
CC   -!- Highly specific; does not act on pyruvate, oxaloacetate,
CC       maleylpyruvate, fumarylpyruvate or acetylacetone.
//
ID   3.7.1.7
DE   Beta-diketone hydrolase.
AN   Oxidized PVA hydrolase.
CA   Nonane-4,6-dione + H(2)O = pentan-2-one + butanoate.
CC   -!- Also acts on the product of the action of EC 1.1.3.18 on polyvinyl
CC       alcohols.
CC   -!- Involved in the bacterial degradation of polyvinyl alcohol.
//
ID   3.7.1.8
DE   2,6-dioxo-6-phenylhexa-3-enoate hydrolase.
AN   HOHPDA hydrolase.
CA   2,6-dioxo-6-phenylhexa-3-enoate + H(2)O = benzoate + 2-oxopent-4-enoate.
CC   -!- Cleaves the products from biphenol, 3-isopropylcatechol and
CC       3-methylcatechol produced by EC 1.13.11.39 by ring-fission at a
CC       -CO-C bond.
CC   -!- Involved in the breakdown of biphenyl-related compounds by
CC       Pseudomonas sp.
DR   Q2VLB9, BPHD_BURCE ;  P47229, BPHD_BURXL ;  Q59324, BPHD_COMTE ;
DR   Q8KRD3, BPHD_DELAC ;  A1VUV0, BPHD_POLNA ;  Q52011, BPHD_PSEPS ;
DR   Q52036, BPHD_PSEPU ;  P17548, BPHD_PSES1 ;  P96851, HSAD_MYCTU ;
DR   Q9KWQ6, HSAD_RHOSR ;
//
ID   3.7.1.9
DE   2-hydroxymuconate-semialdehyde hydrolase.
CA   2-hydroxymuconate semialdehyde + H(2)O = formate + 2-oxopent-4-enoate.
//
ID   3.7.1.10
DE   Cyclohexane-1,3-dione hydrolase.
CA   Cyclohexane-1,3-dione + H(2)O = 5-oxohexanoate.
CC   -!- Highly specific; does not act on other dione derivatives of
CC       cyclohexane, cyclopentane or cycloheptane.
//
ID   3.7.1.11
DE   Cyclohexane-1,2-dione hydrolase.
CA   Cyclohexane-1,2-dione + H(2)O = 6-oxohexanoate.
CC   -!- Highly specific; does not act on cyclohexanone or cyclohexane-1,3-
CC       dione as substrate.
DR   P0CH62, CHDH_AZOSP ;
//
ID   3.7.1.12
DE   Cobalt-precorrin 5A hydrolase.
CA   Cobalt-precorrin-5A + H(2)O = cobalt-precorrin-5B + acetaldehyde +
CA   2 H(+).
CC   -!- This enzyme hydrolyzes the ring A acetate delta-lactone of cobalt-
CC       precorrin-5A resulting in the loss of the C-20 carbon and its
CC       attached methyl group in the form of acetaldehyde.
CC   -!- This is a key reaction in the contraction of the porphyrin-type
CC       tetrapyrrole ring and its conversion to a corrin ring in the
CC       anaerobic (early cobalt insertion) adenosylcobalamin biosynthesis
CC       pathway.
//
ID   3.7.1.13
DE   2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase.
CA   (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H(2)O =
CA   anthranilate + (2E)-2-hydroxypenta-2,4-dienoate.
CC   -!- This enzyme catalyzes the third step in the aerobic degradation
CC       pathway of carbazole.
CC   -!- The effect of the presence of an amino group or hydroxyl group at the
CC       2-position of the substrate is small.
CC   -!- The enzyme has no cofactor requirement.
//
ID   3.7.1.n1
DE   2-hydroxy-6-oxonona-2,4-dienedioate hydrolase.
CA   (1) 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate + H(2)O = 2-hydroxypenta-
CA   2,4-dienoate + succinate.
CA   (2) 2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioate + H(2)O = 2-hydroxypenta-
CA   2,4-dienoate + fumarate.
CC   -!- This enzyme catalyzes a step in the pathway degrading different
CC       phenylpropanoid compounds, with the other enzymes involved being
CC       EC 1.14.13.n3, EC 1.13.11.16, EC 4.2.1.80, EC 4.1.3.39,
CC       and EC 1.2.1.10.
DR   Q47HL4, MHPC1_DECAR;  Q49KF8, MHPC1_PSEPU;  Q47GC1, MHPC2_DECAR;
DR   Q400K3, MHPC2_PSEPU;  B2JQW2, MHPC_BURP8 ;  A4JPX5, MHPC_BURVG ;
DR   Q13QH4, MHPC_BURXL ;  Q8KZP5, MHPC_COMTE ;  Q476M7, MHPC_CUPPJ ;
DR   A7ZI96, MHPC_ECO24 ;  B7L505, MHPC_ECO55 ;  Q8X5K0, MHPC_ECO57 ;
DR   B7NK06, MHPC_ECO7I ;  B7MPB6, MHPC_ECO81 ;  B7M2Z7, MHPC_ECO8A ;
DR   B1XBJ6, MHPC_ECODH ;  A7ZWZ6, MHPC_ECOHS ;  P77044, MHPC_ECOLI ;
DR   B7N8Q6, MHPC_ECOLU ;  B6HZX5, MHPC_ECOSE ;  A6TAC7, MHPC_KLEP7 ;
DR   Q52532, MHPC_PSESP ;
//
ID   3.7.1.n2
DE   3,5/4-trihydroxycyclohexa-1,2-dione hydrolase.
AN   THcHDO hydrolase.
CA   3,5/4-trihydroxycyclohexa-1,2-dione + H(2)O = 5-deoxy-glucuronic acid.
CF   Magnesium; Thiamine diphosphate.
CC   -!- Part of the myo-inositol/D-chiro-inositol degradation pathway leading
CC       to acetyl-CoA together with EC 1.1.1.n6, EC 5.3.99.n1, EC 4.2.1.44,
CC       EC 5.3.1.n1, EC 2.7.1.92, EC 4.1.2.29 and EC 1.2.1.18.
DR   Q63B73, IOLD1_BACCZ;  Q4V1F5, IOLD2_BACCZ;  A7ZAH8, IOLD_BACA2 ;
DR   C3PAZ3, IOLD_BACAA ;  C3LHY1, IOLD_BACAC ;  A0REB6, IOLD_BACAH ;
DR   Q81QB5, IOLD_BACAN ;  B7JPM3, IOLD_BACC0 ;  C1EVJ3, IOLD_BACC3 ;
DR   Q9KAG9, IOLD_BACHD ;  Q6HIK2, IOLD_BACHK ;  Q65D03, IOLD_BACLD ;
DR   Q5WKY8, IOLD_BACSK ;  P42415, IOLD_BACSU ;  B2V4K0, IOLD_CLOBA ;
DR   B2TJ86, IOLD_CLOBB ;  Q0TUZ2, IOLD_CLOP1 ;  Q8XP76, IOLD_CLOPE ;
DR   Q898E8, IOLD_CLOTE ;  Q5KYR0, IOLD_GEOKA ;  A4IPB6, IOLD_GEOTN ;
DR   A5YBJ6, IOLD_LACCA ;  Q92EQ4, IOLD_LISIN ;  Q723S8, IOLD_LISMF ;
DR   Q8Y9Y1, IOLD_LISMO ;
//
ID   3.8.1.1
DE   Alkylhalidase.
AN   Halogenase.
CA   Bromochloromethane + H(2)O = formaldehyde + bromide + chloride.
//
ID   3.8.1.2
DE   (S)-2-haloacid dehalogenase.
AN   2-haloacid dehalogenase.
AN   2-haloacid halidohydrolase.
AN   2-haloalkanoic acid dehalogenase.
AN   2-haloalkanoid acid halidohydrolase.
AN   2-halocarboxylic acid dehalogenase II.
AN   DL-2-haloacid dehalogenase.
AN   Halocarboxylic acid halidohydrolase.
AN   L-2-haloacid dehalogenase.
AN   L-DEX.
CA   (S)-2-haloacid + H(2)O = (R)-2-hydroxyacid + halide.
CC   -!- Acts on acids of short chain lengths, C(2) to C(4), with inversion of
CC       configuration at C-2 (see also EC 3.8.1.9, EC 3.8.1.10 and
CC       EC 3.8.1.11).
DR   P24069, HAD1_PSEUC ;  P24070, HAD2_PSEUC ;  Q51645, HAD4_BURCE ;
DR   Q59728, HAD9_PSEPU ;  Q52087, HADL_PSEPU ;  P60527, HAD_AGRTR  ;
DR   Q59666, HAD_PSEFL  ;  Q53464, HAD_PSEUY  ;  Q60099, HAD_XANAU  ;
//
ID   3.8.1.3
DE   Haloacetate dehalogenase.
CA   Haloacetate + H(2)O = glycolate + halide.
DR   Q01398, DEH1_MORSB ;  Q01399, DEH2_MORSB ;  Q1JU72, DEHA_BURSP ;
DR   Q6NAM1, DEHA_RHOPA ;
//
ID   3.8.1.4
DE   Transferred entry: 1.97.1.10.
//
ID   3.8.1.5
DE   Haloalkane dehalogenase.
AN   1-chlorohexane halidohydrolase.
CA   1-haloalkane + H(2)O = a primary alcohol + halide.
CC   -!- Acts on a wide range of 1-haloalkanes, haloalcohols, haloalkenes and
CC       some haloaromatic compounds.
DR   Q8U671, DHAA_AGRT5 ;  P59337, DHAA_BRAJA ;  Q9XB14, DHAA_MYCBO ;
DR   A1KLS7, DHAA_MYCBP ;  C1AF48, DHAA_MYCBT ;  Q938B4, DHAA_MYCS2 ;
DR   Q9ZER0, DHAA_MYCSX ;  A5U5S9, DHAA_MYCTA ;  Q50642, DHAA_MYCTU ;
DR   P0A3G4, DHAA_PSEPV ;  Q98C03, DHAA_RHILO ;  P0A3G2, DHAA_RHORH ;
DR   P59336, DHAA_RHOSD ;  P0A3G3, DHAA_RHOSO ;  P22643, DHLA_XANAU ;
DR   Q6Q3H0, DHLA_XANFL ;  P64302, DHMA1_MYCBO;  P64301, DHMA1_MYCTU;
DR   P64304, DHMA2_MYCBO;  P64303, DHMA2_MYCTU;  B8H3S9, DHMA_CAUCN ;
DR   Q9A919, DHMA_CAUCR ;  B0SY51, DHMA_CAUSK ;  Q93K00, DHMA_MYCAV ;
DR   B2HJU9, DHMA_MYCMM ;  Q73Y99, DHMA_MYCPA ;  B4RF90, DHMA_PHEZH ;
DR   Q1QBB9, DHMA_PSYCK ;  P51698, LINB_PSEPA ;
//
ID   3.8.1.6
DE   4-chlorobenzoate dehalogenase.
CA   4-chlorobenzoate + H(2)O = 4-hydroxybenzoate + chloride.
CC   -!- Catalyzes the first step in the degradation of chlorobenzoate in
CC       Pseudomonas.
CC   -!- In many microorganisms, this activity comprises three separate
CC       enzymes, EC 6.2.1.33, EC 3.8.1.7 and EC 3.1.2.23.
PR   PROSITE; PDOC00150;
//
ID   3.8.1.7
DE   4-chlorobenzoyl-CoA dehalogenase.
CA   4-chlorobenzoyl-CoA + H(2)O = 4-hydroxybenzoyl CoA + chloride.
CC   -!- Specific for dehalogenation at the 4-position.
CC   -!- Can dehalogenate substrates bearing fluorine, chlorine, bromine and
CC       iodine in the 4-position.
CC   -!- This enzyme is part of the bacterial 2,4-dichlorobenzoate degradation
CC       pathway.
DR   O85078, CBAD1_ARTSP;  Q9LCU3, CBAD2_ARTSP;  A5JTM5, CBADH_PSEUC;
//
ID   3.8.1.8
DE   Atrazine chlorohydrolase.
CA   Atrazine + H(2)O = 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-
CA   triazine + HCl.
CC   -!- Involved in the degradation of the herbicide atrazine, 2-chloro-4-
CC       (ethylamino)-6-(isopropylamino)-1,3,5-triazine, in bacteria.
DR   P72156, ATZA_PSESD ;
//
ID   3.8.1.9
DE   (R)-2-haloacid dehalogenase.
AN   2-haloalkanoic acid dehalogenase.
AN   2-haloalkanoid acid halidohydrolase.
AN   D-2-haloacid dehalogenase.
AN   D-DEX.
CA   (R)-2-haloacid + H(2)O = (S)-2-hydroxyacid + halide.
CC   -!- Acts on acids of short chain lengths, C(2) to C(4), with inversion of
CC       configuration at C-2 (see also EC 3.8.1.2, EC 3.8.1.10 and
CC       EC 3.8.1.11).
DR   Q52086, HADD_PSEPU ;  Q8KLS9, HADD_RHISH ;
//
ID   3.8.1.10
DE   2-haloacid dehalogenase (configuration-inverting).
AN   2-haloalkanoic acid dehalogenase.
AN   2-haloalkanoid acid halidohydrolase.
AN   DL-2-haloacid dehalogenase.
AN   DL-2-haloacid dehalogenase (inversion of configuration).
AN   DL-2-haloacid halidohydrolase (inversion of configuration).
AN   DL-DEXi.
CA   (1) (S)-2-haloacid + H(2)O = (R)-2-hydroxyacid + halide.
CA   (2) (R)-2-haloacid + H(2)O = (S)-2-hydroxyacid + halide.
CC   -!- Dehalogenates both (S)- and (R)-2-haloalkanoic acids to the
CC       corresponding (R)- and (S)-hydroxyalkanoic acids, respectively, with
CC       inversion of configuration at C-2.
CC   -!- The enzyme from Pseudomonas sp. 113 acts on 2-haloalkanoic acids
CC       whose carbon chain lengths are five or less (see also EC 3.8.1.2,
CC       EC 3.8.1.9 and EC 3.8.1.11).
DR   O06652, HADDL_PSES4;  Q59168, HDDL_ALCXX ;
//
ID   3.8.1.11
DE   2-haloacid dehalogenase (configuration-retaining).
AN   2-haloalkanoic acid dehalogenase.
AN   2-haloalkanoid acid halidohydrolase.
AN   DL-2-haloacid dehalogenase.
AN   DL-DEXr.
CA   (1) (S)-2-haloacid + H(2)O = (S)-2-hydroxyacid + halide.
CA   (2) (R)-2-haloacid + H(2)O = (R)-2-hydroxyacid + halide.
CC   -!- Dehalogenates both (S)- and (R)-2-haloalkanoic acids to the
CC       corresponding (S)- and (R)-hydroxyalkanoic acids, respectively, with
CC       retention of configuration at C-2 (see also EC 3.8.1.2, EC 3.8.1.9
CC       and EC 3.8.1.10).
//
ID   3.8.2.1
DE   Transferred entry: 3.1.8.2.
//
ID   3.9.1.1
DE   Phosphoamidase.
CA   N-phosphocreatine + H(2)O = creatine + phosphate.
CC   -!- Also acts on N-phospho-arginine and other phosphoamides.
CC   -!- Possibly identical with EC 3.1.3.9 or EC 3.1.3.16.
//
ID   3.10.1.1
DE   N-sulfoglucosamine sulfohydrolase.
AN   Sulfoglucosamine sulfamidase.
AN   Sulphamidase.
CA   N-sulfo-D-glucosamine + H(2)O = D-glucosamine + sulfate.
DR   P51688, SPHM_HUMAN ;
//
ID   3.10.1.2
DE   Cyclamate sulfohydrolase.
AN   Cyclamate sulfamatase.
AN   Cyclamate sulfamidase.
CA   Cyclohexylsulfamate + H(2)O = cyclohexylamine + sulfate.
CC   -!- Also readily hydrolyzes aliphatic sulfamates with 3 to 8 carbons.
//
ID   3.11.1.1
DE   Phosphonoacetaldehyde hydrolase.
AN   2-phosphonoacetylaldehyde phosphonohydrolase.
AN   Phosphonatase.
AN   Phosphonoacetylaldehyde phosphonohydrolase.
CA   Phosphonoacetaldehyde + H(2)O = acetaldehyde + phosphate.
CF   Magnesium.
CC   -!- This enzyme destabilizes the C-P bond, by forming an imine between
CC       one of its lysine residues and the carbonyl group of the substrate,
CC       thus allowing this, normally stable, bond to be broken.
CC   -!- The mechanism is similar to that used by EC 4.1.2.13 to break a
CC       C-C bond.
DR   Q183T0, PHNXW_CLOD6;  A0KJM0, PHNX_AERHH ;  B6ES82, PHNX_ALISL ;
DR   A0RBE8, PHNX_BACAH ;  Q81TE1, PHNX_BACAN ;  B7JFQ8, PHNX_BACC0 ;
DR   Q73BH9, PHNX_BACC1 ;  B7IN18, PHNX_BACC2 ;  B7HH80, PHNX_BACC4 ;
DR   B7HK47, PHNX_BACC7 ;  O31156, PHNX_BACCE ;  A7GML9, PHNX_BACCN ;
DR   B9IUR5, PHNX_BACCQ ;  Q81G82, PHNX_BACCR ;  Q63E46, PHNX_BACCZ ;
DR   Q5L9P9, PHNX_BACFN ;  Q64PZ2, PHNX_BACFR ;  Q6HLM1, PHNX_BACHK ;
DR   A9VKQ2, PHNX_BACWK ;  Q2L1W2, PHNX_BORA1 ;  Q7WL48, PHNX_BORBR ;
DR   Q7W7R1, PHNX_BORPA ;  Q7VWH8, PHNX_BORPE ;  B2T4N1, PHNX_BURPP ;
DR   Q13YI8, PHNX_BURXL ;  B8DKP2, PHNX_DESVM ;  Q2SHM4, PHNX_HAHCH ;
DR   A6TFW3, PHNX_KLEP7 ;  Q88YN8, PHNX_LACPL ;  Q38V12, PHNX_LACSS ;
DR   B1HPR7, PHNX_LYSSC ;  A6LFV1, PHNX_PARD8 ;  A6V8P9, PHNX_PSEA7 ;
DR   B7UVR5, PHNX_PSEA8 ;  Q02JF2, PHNX_PSEAB ;  Q9I433, PHNX_PSEAE ;
DR   Q1I7T9, PHNX_PSEE4 ;  Q4K9L7, PHNX_PSEF5 ;  C3JYI3, PHNX_PSEFS ;
DR   A5W696, PHNX_PSEP1 ;  Q3K9Y2, PHNX_PSEPF ;  Q88KT1, PHNX_PSEPK ;
DR   Q8RSQ3, PHNX_PSEPU ;  B1JBM6, PHNX_PSEPW ;  A1SY91, PHNX_PSYIN ;
DR   B5EXH2, PHNX_SALA4 ;  Q57SD2, PHNX_SALCH ;  B5FKT7, PHNX_SALDC ;
DR   B5QTI0, PHNX_SALEP ;  B5R6T3, PHNX_SALG2 ;  B4T9C7, PHNX_SALHS ;
DR   B4SWS4, PHNX_SALNS ;  Q5PFR1, PHNX_SALPA ;  A9MWZ8, PHNX_SALPB ;
DR   C0Q7V6, PHNX_SALPC ;  B5BDA0, PHNX_SALPK ;  B4TMB2, PHNX_SALSV ;
DR   Q8Z8W5, PHNX_SALTI ;  Q7ZAP3, PHNX_SALTY ;  A0LMC1, PHNX_SYNFM ;
DR   A5F051, PHNX_VIBC3 ;  Q9KLY5, PHNX_VIBCH ;  C3LVM1, PHNX_VIBCM ;
DR   A7N333, PHNX_VIBHB ;  Q87JL6, PHNX_VIBPA ;  Q8D3M6, PHNX_VIBVU ;
DR   Q7MF46, PHNX_VIBVY ;
//
ID   3.11.1.2
DE   Phosphonoacetate hydrolase.
CA   Phosphonoacetate + H(2)O = acetate + phosphate.
CF   Zinc.
DR   P86807, PHNHY_PENOX;  Q50HR5, PHNHY_PSECE;  Q51782, PHNHY_PSEFL;
DR   Q50HR6, PHNHY_PSEPU;
//
ID   3.11.1.3
DE   Phosphonopyruvate hydrolase.
AN   PPH.
CA   3-phosphonopyruvate + H(2)O = pyruvate + phosphate.
CF   Cobalt or manganese or magnesium.
CC   -!- Highly specific for phosphonopyruvate as substrate.
CC   -!- The reaction is not inhibited by phosphate but is inhibited by the
CC       phosphonates phosphonoformic acid, hydroxymethylphosphonic acid and
CC       3-phosphonopropanoic acid.
DR   Q84G06, PPHA_VARSP ;
//
ID   3.12.1.1
DE   Trithionate hydrolase.
CA   Trithionate + H(2)O = thiosulfate + sulfate + 2 H(+).
//
ID   3.13.1.1
DE   UDP-sulfoquinovose synthase.
AN   Sulfite:UDP-glucose sulfotransferase.
CA   UDP-alpha-D-glucose + sulfite = UDP-alpha-D-sulfoquinovose + H(2)O.
CF   NAD.
CC   -!- NAD(+) appears to oxidize the substrate to UDP-4-dehydroglucose,
CC       which dehydrates to UDP-4-dehydro-6-deoxygluc-5-enose, to which
CC       sulfite can add; the reaction is completed when the substrate is
CC       rehydrogenated at C-4.
CC   -!- The enzyme from Arabidopsis thaliana is specific for UDP-Glc and
CC       sulfite.
DR   O48917, SQD1_ARATH ;  Q84KI6, SQD1_SPIOL ;
//
ID   3.13.1.2
DE   Deleted entry.
//
ID   3.13.1.3
DE   2'-hydroxybiphenyl-2-sulfinate desulfinase.
AN   2-(2'-hydroxyphenyl)benzenesulfinate desulfinase.
AN   2-(2-hydroxyphenyl) benzenesulfinate sulfohydrolase.
AN   2-(2-hydroxyphenyl) benzenesulfinate:H(2)O hydrolase.
AN   2-(2-hydroxyphenyl)benzenesulfinate desulfinase.
AN   2-(2-hydroxyphenyl)benzenesulfinate hydrolase.
AN   Dibenzothiophene desulfurization enzyme B.
AN   HBPSi desulfinase.
AN   HPBS desulfinase.
CA   2'-hydroxybiphenyl-2-sulfinate + H(2)O = 2-hydroxybiphenyl + sulfite.
CF   FMN.
CC   -!- The enzyme has a narrow substrate specificity with biphenyl-2-
CC       sulfinate being the only other substrate known to date.
CC   -!- Formerly EC 3.1.2.24.
DR   P54997, SOXB_RHOSG ;
//
ID   4.1.1.1
DE   Pyruvate decarboxylase.
AN   2-oxo-acid carboxy-lyase.
AN   Alpha-carboxylase.
AN   Alpha-ketoacid carboxylase.
AN   Pyruvic decarboxylase.
CA   A 2-oxo acid = an aldehyde + CO(2).
CF   Thiamine diphosphate.
CC   -!- Also catalyzes acyloin formation.
PR   PROSITE; PDOC00166;
DR   P83779, PDC1_CANAL ;  Q6FJA3, PDC1_CANGA ;  Q12629, PDC1_KLULA ;
DR   P33149, PDC1_KLUMA ;  P28516, PDC1_MAIZE ;  A2Y5L9, PDC1_ORYSI ;
DR   Q0DHF6, PDC1_ORYSJ ;  P51850, PDC1_PEA   ;  Q09737, PDC1_SCHPO ;
DR   P51845, PDC1_TOBAC ;  P06169, PDC1_YEAST ;  Q05326, PDC2_MAIZE ;
DR   A2XFI3, PDC2_ORYSI ;  Q10MW3, PDC2_ORYSJ ;  P51851, PDC2_PEA   ;
DR   Q92345, PDC2_SCHPO ;  P51846, PDC2_TOBAC ;  Q05327, PDC3_MAIZE ;
DR   A2YQ76, PDC3_ORYSI ;  Q0D3D2, PDC3_ORYSJ ;  Q9P7P6, PDC3_SCHPO ;
DR   O42873, PDC4_SCHPO ;  P16467, PDC5_YEAST ;  P26263, PDC6_YEAST ;
DR   Q4WXX9, PDC_ASPFU  ;  Q2UKV4, PDC_ASPOR  ;  P51844, PDC_ASPPA  ;
DR   Q0CNV1, PDC_ASPTN  ;  P87208, PDC_EMENI  ;  P34734, PDC_HANUV  ;
DR   P33287, PDC_NEUCR  ;  P06672, PDC_ZYMMO  ;
//
ID   4.1.1.2
DE   Oxalate decarboxylase.
AN   Oxalate carboxy-lyase.
CA   Oxalate = formate + CO(2).
CF   Manganese.
DR   O34714, OXDC_BACSU ;  O34767, OXDD_BACSU ;
//
ID   4.1.1.3
DE   Oxaloacetate decarboxylase.
AN   Oxalate beta-decarboxylase.
AN   Oxaloacetate carboxy-lyase.
CA   Oxaloacetate = pyruvate + CO(2).
CF   Biotin; Sodium or manganese.
CC   -!- The enzyme from Klebsiella aerogenes is a biotinyl protein and also
CC       decarboxylates glutaconyl-CoA and methylmalonyl-CoA.
CC   -!- The process is accompanied by the extrusion of two sodium ions from
CC       cells.
CC   -!- Some animal enzymes require manganese.
PR   PROSITE; PDOC00167;
PR   PROSITE; PDOC50991;
DR   P13187, DCOA_KLEPN ;  Q8XGX8, DCOA_SALTI ;  Q03030, DCOA_SALTY ;
DR   Q9AQI0, HMGA_PSEOC ;  Q8Z9M6, OADB1_SALTI;  Q8ZRY4, OADB1_SALTY;
DR   Q8Z3E5, OADB2_SALTI;  Q03031, OADB2_SALTY;  Q9RF98, OADB_HAEDU ;
DR   P13156, OADB_KLEPN ;  Q9CL24, OADB_PASMU ;  Q9KTU5, OADB_VIBCH ;
DR   Q3KEL1, OADC1_PSEPF;  B1J195, OADC1_PSEPW;  Q3KCJ2, OADC2_PSEPF;
DR   B1JFP4, OADC2_PSEPW;  C1DEN4, OADC_AZOVD ;  Q89JL7, OADC_BRAJA ;
DR   A5EL79, OADC_BRASB ;  A4YT21, OADC_BRASO ;  Q13Q00, OADC_BURXL ;
DR   Q1R0Z3, OADC_CHRSD ;  A6VZF8, OADC_MARMS ;  Q48LY6, OADC_PSE14 ;
DR   A6VCY0, OADC_PSEA7 ;  B7V1T5, OADC_PSEA8 ;  Q02FE6, OADC_PSEAB ;
DR   Q9HUU1, OADC_PSEAE ;  Q1I5P3, OADC_PSEE4 ;  Q4KDX1, OADC_PSEF5 ;
DR   C3KBB4, OADC_PSEFS ;  A4XQ41, OADC_PSEMY ;  A5W8J7, OADC_PSEP1 ;
DR   B0KV77, OADC_PSEPG ;  Q88N27, OADC_PSEPK ;  Q886Y2, OADC_PSESM ;
DR   Q4ZX15, OADC_PSEU2 ;  A4VQV5, OADC_PSEU5 ;  Q2IXI7, OADC_RHOP2 ;
DR   Q07L14, OADC_RHOP5 ;  Q6N509, OADC_RHOPA ;  Q211P3, OADC_RHOPB ;
DR   Q135C1, OADC_RHOPS ;  B3QAW1, OADC_RHOPT ;  Q5PKI8, OADG1_SALPA;
DR   Q8Z9M5, OADG1_SALTI;  P58651, OADG1_SALTY;  Q9KUH2, OADG1_VIBCH;
DR   Q5PJT2, OADG2_SALPA;  Q8Z3E4, OADG2_SALTI;  Q03032, OADG2_SALTY;
DR   Q9KTU4, OADG2_VIBCH;  P58650, OADG3_SALTY;  A3N223, OADG_ACTP2 ;
DR   B3GYF4, OADG_ACTP7 ;  A6VL34, OADG_ACTSZ ;  B7LVP2, OADG_ESCF3 ;
DR   Q9RFA0, OADG_HAEDU ;  A6T4H1, OADG_KLEP7 ;  P13155, OADG_KLEPN ;
DR   Q65WL3, OADG_MANSM ;  Q9CL26, OADG_PASMU ;  B5F736, OADG_SALA4 ;
DR   A9MYH6, OADG_SALPB ;  Q87LR6, OADG_VIBPA ;  Q8DC44, OADG_VIBVU ;
DR   Q7MHR9, OADG_VIBVY ;
//
ID   4.1.1.4
DE   Acetoacetate decarboxylase.
AN   Acetoacetate carboxy-lyase.
CA   Acetoacetate = acetone + CO(2).
DR   Q89CN4, ADC1_BRAJA ;  Q98AN6, ADC1_RHILO ;  Q89EP4, ADC2_BRAJA ;
DR   Q98IH6, ADC2_RHILO ;  Q98FS9, ADC3_RHILO ;  A5FVT7, ADC_ACICJ  ;
DR   B2IJF4, ADC_BEII9  ;  Q2L048, ADC_BORA1  ;  B1YXQ0, ADC_BURA4  ;
DR   Q1BK36, ADC_BURCA  ;  B1K259, ADC_BURCC  ;  A0B471, ADC_BURCH  ;
DR   B4EG09, ADC_BURCJ  ;  Q0B5P1, ADC_BURCM  ;  A9AR15, ADC_BURM1  ;
DR   A3MAE3, ADC_BURM7  ;  A2RZY1, ADC_BURM9  ;  Q62EK3, ADC_BURMA  ;
DR   Q3JIC1, ADC_BURP1  ;  B2T319, ADC_BURPP  ;  Q63PC7, ADC_BURPS  ;
DR   Q38ZU0, ADC_BURS3  ;  A4JKF7, ADC_BURVG  ;  Q141C9, ADC_BURXL  ;
DR   Q7NSA6, ADC_CHRVO  ;  P23670, ADC_CLOAB  ;  A6M020, ADC_CLOB8  ;
DR   B2TLN8, ADC_CLOBB  ;  Q9RPK1, ADC_CLOBE  ;  P81336, ADC_CLOPA  ;
DR   B2UIG7, ADC_RALPJ  ;  Q8XR10, ADC_RALSO  ;  Q9EYI7, ADC_STRNO  ;
//
ID   4.1.1.5
DE   Acetolactate decarboxylase.
AN   (S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase.
CA   (2S)-2-hydroxy-2-methyl-3-oxobutanoate = (3R)-3-hydroxybutan-2-one +
CA   CO(2).
DR   Q65E52, ALDC_BACLD ;  Q04777, ALDC_BACSU ;  P23616, ALDC_BREBE ;
DR   P05361, ALDC_ENTAE ;  P95676, ALDC_LACLA ;  P77880, ALDC_LACLM ;
DR   Q607C3, ALDC_METCA ;  Q8PZ55, ALDC_METMA ;  Q04518, ALDC_RAOTE ;
DR   Q8L208, ALDC_STRTR ;  Q9KRP7, ALDC_VIBCH ;
//
ID   4.1.1.6
DE   Aconitate decarboxylase.
AN   CAD.
AN   Cis-aconitate carboxy-lyase.
AN   Cis-aconitic decarboxylase.
CA   Cis-aconitate = itaconate + CO(2).
//
ID   4.1.1.7
DE   Benzoylformate decarboxylase.
AN   Benzoylformate carboxy-lyase.
CA   Benzoylformate = benzaldehyde + CO(2).
CF   Thiamine diphosphate.
PR   PROSITE; PDOC00166;
DR   Q9HUR2, MDLC_PSEAE ;  P20906, MDLC_PSEPU ;
//
ID   4.1.1.8
DE   Oxalyl-CoA decarboxylase.
AN   Oxalyl-CoA carboxy-lyase.
CA   Oxalyl-CoA = formyl-CoA + CO(2).
CF   Thiamine diphosphate.
DR   P0AFI1, OXC_ECO57  ;  P0AFI0, OXC_ECOLI  ;  P40149, OXC_OXAFO  ;
//
ID   4.1.1.9
DE   Malonyl-CoA decarboxylase.
AN   Malonyl-CoA carboxy-lyase.
CA   Malonyl-CoA = acetyl-CoA + CO(2).
CC   -!- Specific for malonyl-CoA.
CC   -!- The enzyme from Pseudomonas ovalis also catalyzes the reaction of
CC       EC 2.8.3.3.
DR   P12617, DCMC_ANSAN ;  O95822, DCMC_HUMAN ;  Q99J39, DCMC_MOUSE ;
DR   Q920F5, DCMC_RAT   ;
//
ID   4.1.1.10
DE   Transferred entry: 4.1.1.12.
//
ID   4.1.1.11
DE   Aspartate 1-decarboxylase.
AN   Aspartate alpha-decarboxylase.
AN   L-aspartate 1-carboxy-lyase.
CA   L-aspartate = beta-alanine + CO(2).
CF   Pyruvate.
DR   A1RDH3, PAND1_ARTAT;  Q2JE00, PAND1_FRASC;  Q7NCY1, PAND1_GLOVI;
DR   Q12F35, PAND1_POLSJ;  Q9EYU1, PAND1_RHILO;  A1RAZ4, PAND2_ARTAT;
DR   Q2J4S0, PAND2_FRASC;  Q7NDK7, PAND2_GLOVI;  Q12D75, PAND2_POLSJ;
DR   Q982G0, PAND2_RHILO;  B0C321, PAND_ACAM1 ;  Q6F8I6, PAND_ACIAD ;
DR   B7GYR1, PAND_ACIB3 ;  B7I7B4, PAND_ACIB5 ;  B2HUM1, PAND_ACIBC ;
DR   B0VTX3, PAND_ACIBS ;  A3M2W9, PAND_ACIBT ;  B0V8G1, PAND_ACIBY ;
DR   A0LRC6, PAND_ACIC1 ;  B9MEY1, PAND_ACIET ;  A1WBI2, PAND_ACISJ ;
DR   Q8U9Q9, PAND_AGRT5 ;  Q0VSR5, PAND_ALCBS ;  Q0AB67, PAND_ALHEH ;
DR   B8JAL2, PAND_ANAD2 ;  Q2IGV9, PAND_ANADE ;  A7H796, PAND_ANADF ;
DR   B4UHC8, PAND_ANASK ;  B9ML76, PAND_ANATD ;  Q3M782, PAND_ANAVT ;
DR   B7GHT2, PAND_ANOFW ;  O66773, PAND_AQUAE ;  A8ERX9, PAND_ARCB4 ;
DR   B8H729, PAND_ARTCA ;  A0K1U2, PAND_ARTS2 ;  C1DFK0, PAND_AZOVD ;
DR   A7Z5Z2, PAND_BACA2 ;  C3P5R1, PAND_BACAA ;  C3L8P8, PAND_BACAC ;
DR   A0RBZ4, PAND_BACAH ;  Q81ST1, PAND_BACAN ;  B7JHQ8, PAND_BACC0 ;
DR   Q73AV2, PAND_BACC1 ;  B7IPB9, PAND_BACC2 ;  C1EN38, PAND_BACC3 ;
DR   B7HHU5, PAND_BACC4 ;  B7HL55, PAND_BACC7 ;  A7GN78, PAND_BACCN ;
DR   B9IVR3, PAND_BACCQ ;  Q81FN5, PAND_BACCR ;  Q63DJ1, PAND_BACCZ ;
DR   Q5LGS0, PAND_BACFN ;  Q64XM2, PAND_BACFR ;  Q9KC85, PAND_BACHD ;
DR   Q6HL14, PAND_BACHK ;  Q65I58, PAND_BACLD ;  A8FEH5, PAND_BACP2 ;
DR   Q5WGA5, PAND_BACSK ;  P52999, PAND_BACSU ;  Q89ZR7, PAND_BACTN ;
DR   A6L4C4, PAND_BACV8 ;  A9VMF1, PAND_BACWK ;  Q6MHH9, PAND_BDEBA ;
DR   B2IEX5, PAND_BEII9 ;  Q2KY48, PAND_BORA1 ;  Q7WHJ6, PAND_BORBR ;
DR   Q7W972, PAND_BORPA ;  Q7VXF8, PAND_BORPE ;  Q9AMS6, PAND_BRAJA ;
DR   B1YUU0, PAND_BURA4 ;  Q1BUH0, PAND_BURCA ;  B1JWS9, PAND_BURCC ;
DR   A0K9L6, PAND_BURCH ;  B4E8E6, PAND_BURCJ ;  Q0BCS7, PAND_BURCM ;
DR   A9AHJ2, PAND_BURM1 ;  A3MLN3, PAND_BURM7 ;  A2SAE9, PAND_BURM9 ;
DR   Q62LE8, PAND_BURMA ;  A1V5W9, PAND_BURMS ;  A3NSK7, PAND_BURP0 ;
DR   Q3JUY9, PAND_BURP1 ;  A3N6X1, PAND_BURP6 ;  B2JEQ8, PAND_BURP8 ;
DR   B2T171, PAND_BURPP ;  Q63W98, PAND_BURPS ;  Q39DU8, PAND_BURS3 ;
DR   Q2T096, PAND_BURTA ;  A4JGX2, PAND_BURVG ;  Q143J3, PAND_BURXL ;
DR   A4XMZ2, PAND_CALS8 ;  A7ZFX6, PAND_CAMC1 ;  A7H0Y2, PAND_CAMC5 ;
DR   A0RM41, PAND_CAMFF ;  A7HZW6, PAND_CAMHC ;  A8FK85, PAND_CAMJ8 ;
DR   A7H576, PAND_CAMJD ;  Q9PIK3, PAND_CAMJE ;  Q29W39, PAND_CAMJJ ;
DR   Q5HWH5, PAND_CAMJR ;  Q3A9L2, PAND_CARHZ ;  B8GYS2, PAND_CAUCN ;
DR   Q9A602, PAND_CAUCR ;  B0T725, PAND_CAUSK ;  B3PCR4, PAND_CELJU ;
DR   Q3AQL9, PAND_CHLCH ;  B3EFC1, PAND_CHLL2 ;  B3QQH1, PAND_CHLP8 ;
DR   B3ELP8, PAND_CHLPB ;  A1BDG1, PAND_CHLPD ;  B3QTQ3, PAND_CHLT3 ;
DR   Q8KFS0, PAND_CHLTE ;  Q1QSZ7, PAND_CHRSD ;  Q7NXI9, PAND_CHRVO ;
DR   A8ALF1, PAND_CITK8 ;  A5CNC0, PAND_CLAM3 ;  P58285, PAND_CLOAB ;
DR   A7FR58, PAND_CLOB1 ;  C3L033, PAND_CLOB6 ;  A6LWN4, PAND_CLOB8 ;
DR   B2V1M0, PAND_CLOBA ;  B1IEL4, PAND_CLOBK ;  A7GAI4, PAND_CLOBL ;
DR   B1KUY5, PAND_CLOBM ;  B8I2Z2, PAND_CLOCE ;  B9E234, PAND_CLOK1 ;
DR   A5N8N4, PAND_CLOK5 ;  A0PXQ5, PAND_CLONN ;  A3DDV5, PAND_CLOTH ;
DR   B5Y862, PAND_COPPD ;  Q8FU86, PAND_COREF ;  A4QAD0, PAND_CORGB ;
DR   Q9X4N0, PAND_CORGL ;  Q4JXL3, PAND_CORJK ;  B1VHK2, PAND_CORU7 ;
DR   Q83EA4, PAND_COXBU ;  Q9ZHI5, PAND_CUPNH ;  B3R6Q3, PAND_CUPTR ;
DR   B1WSW1, PAND_CYAA5 ;  B7K6Z1, PAND_CYAP7 ;  B7JX32, PAND_CYAP8 ;
DR   Q11NE7, PAND_CYTH3 ;  Q47B64, PAND_DECAR ;  Q3Z8B5, PAND_DEHE1 ;
DR   Q3ZXG1, PAND_DEHSC ;  C1D1G6, PAND_DEIDV ;  Q1IYG7, PAND_DEIGD ;
DR   Q9RWF1, PAND_DEIRA ;  A9BV13, PAND_DELAS ;  B1I1N9, PAND_DESAP ;
DR   B8IZG2, PAND_DESDA ;  B8FZE1, PAND_DESHD ;  Q251P1, PAND_DESHY ;
DR   Q6ALV4, PAND_DESPS ;  A7ZHM0, PAND_ECO24 ;  B7UIH9, PAND_ECO27 ;
DR   B7MBB4, PAND_ECO45 ;  B7LGJ3, PAND_ECO55 ;  P0A792, PAND_ECO57 ;
DR   B5YZG7, PAND_ECO5E ;  B7NI91, PAND_ECO7I ;  B7MNZ3, PAND_ECO81 ;
DR   B7M172, PAND_ECO8A ;  C4ZRM4, PAND_ECOBW ;  B1XCA6, PAND_ECODH ;
DR   A7ZW80, PAND_ECOHS ;  A1A7H7, PAND_ECOK1 ;  Q0TLK2, PAND_ECOL5 ;
DR   P0A791, PAND_ECOL6 ;  B1IQK9, PAND_ECOLC ;  P0A790, PAND_ECOLI ;
DR   B7N801, PAND_ECOLU ;  P0C7I4, PAND_ECOLW ;  B6HZA6, PAND_ECOSE ;
DR   B1LGT2, PAND_ECOSM ;  Q1RG60, PAND_ECOUT ;  C5B9K4, PAND_EDWI9 ;
DR   A4W6N6, PAND_ENT38 ;  Q833S7, PAND_ENTFA ;  A7MGP8, PAND_ENTS8 ;
DR   Q6D1X4, PAND_ERWCT ;  B2VD17, PAND_ERWT9 ;  B7LW38, PAND_ESCF3 ;
DR   C4ZG24, PAND_EUBR3 ;  B1YHQ7, PAND_EXIS2 ;  C4L6Q2, PAND_EXISA ;
DR   A7HLE9, PAND_FERNB ;  A6GVV2, PAND_FLAPJ ;  Q0RB93, PAND_FRAAA ;
DR   A8LCM7, PAND_FRASN ;  Q14GK9, PAND_FRAT1 ;  Q2A4C8, PAND_FRATH ;
DR   A0Q7L4, PAND_FRATN ;  Q0BMQ7, PAND_FRATO ;  Q5NF56, PAND_FRATT ;
DR   A4IWW4, PAND_FRATW ;  B5E844, PAND_GEOBB ;  Q5KXX4, PAND_GEOKA ;
DR   C6E3N6, PAND_GEOSM ;  C5D3B1, PAND_GEOSW ;  A4IQ59, PAND_GEOTN ;
DR   A5G3A2, PAND_GEOUR ;  A0M786, PAND_GRAFK ;  A1WUU3, PAND_HALHL ;
DR   Q18HQ3, PAND_HALWD ;  Q17ZL6, PAND_HELAH ;  Q7VJB2, PAND_HELHP ;
DR   B0TBP6, PAND_HELMI ;  B6JPC9, PAND_HELP2 ;  Q1CVC3, PAND_HELPH ;
DR   Q9ZN30, PAND_HELPJ ;  B2UW36, PAND_HELPS ;  P56065, PAND_HELPY ;
DR   A9AUB8, PAND_HERA2 ;  A4G215, PAND_HERAR ;  B4U8K0, PAND_HYDS0 ;
DR   Q0C2E7, PAND_HYPNA ;  B2GGA2, PAND_KOCRD ;  C5CEQ3, PAND_KOSOT ;
DR   Q88Z02, PAND_LACPL ;  C1D7F0, PAND_LARHH ;  Q5X0V0, PAND_LEGPA ;
DR   Q5ZRF3, PAND_LEGPH ;  Q5WSM2, PAND_LEGPL ;  B0SBX0, PAND_LEPBA ;
DR   Q04TD7, PAND_LEPBJ ;  Q052G3, PAND_LEPBL ;  B0STF1, PAND_LEPBP ;
DR   B1Y852, PAND_LEPCP ;  Q72QN9, PAND_LEPIC ;  Q8CVE9, PAND_LEPIN ;
DR   Q92AA8, PAND_LISIN ;  C1KWK0, PAND_LISMC ;  Q71YB5, PAND_LISMF ;
DR   B8DC26, PAND_LISMH ;  Q8Y603, PAND_LISMO ;  A0AK05, PAND_LISW6 ;
DR   Q2VZZ9, PAND_MAGSA ;  Q0AMS2, PAND_MARMM ;  A6VUR3, PAND_MARMS ;
DR   Q605G8, PAND_METCA ;  Q1H3S3, PAND_METFK ;  B8IQG9, PAND_METNO ;
DR   A2SLT3, PAND_METPP ;  B8ELJ7, PAND_METSB ;  B0JNW2, PAND_MICAN ;
DR   C5C713, PAND_MICLC ;  Q2RM59, PAND_MOOTA ;  A0QA94, PAND_MYCA1 ;
DR   P65661, PAND_MYCBO ;  A1KPT6, PAND_MYCBP ;  C1AI59, PAND_MYCBT ;
DR   A4T5N4, PAND_MYCGI ;  B8ZU50, PAND_MYCLB ;  Q9CD57, PAND_MYCLE ;
DR   Q743Y4, PAND_MYCPA ;  A0QNF3, PAND_MYCS2 ;  A3Q6Y4, PAND_MYCSJ ;
DR   A1UMH9, PAND_MYCSK ;  Q1B2L9, PAND_MYCSS ;  A5U8S6, PAND_MYCTA ;
DR   P65660, PAND_MYCTU ;  A0PV49, PAND_MYCUA ;  A1TG34, PAND_MYCVP ;
DR   Q1CXC6, PAND_MYXXD ;  B9L6T1, PAND_NAUPA ;  Q5F8Y9, PAND_NEIG1 ;
DR   B4RMD5, PAND_NEIG2 ;  Q9JU49, PAND_NEIMA ;  Q9JZ56, PAND_NEIMB ;
DR   A1KUB3, PAND_NEIMF ;  Q3JCP7, PAND_NITOC ;  Q5Z2U2, PAND_NOCFA ;
DR   A1SDW8, PAND_NOCSJ ;  B2J9T1, PAND_NOSP7 ;  Q8YR79, PAND_NOSS1 ;
DR   Q8EQD8, PAND_OCEIH ;  A6L8I7, PAND_PARD8 ;  C6DC49, PAND_PECCP ;
DR   Q3A3I8, PAND_PELCD ;  Q3B208, PAND_PELLD ;  B4SCF6, PAND_PELPB ;
DR   A1AUV5, PAND_PELPD ;  A5D5T6, PAND_PELTS ;  C0QRI3, PAND_PERMH ;
DR   B4RH30, PAND_PHEZH ;  Q7N871, PAND_PHOLL ;  A1VKS5, PAND_POLNA ;
DR   A4SWK6, PAND_POLSQ ;  B2RK28, PAND_PORG3 ;  Q7MVF1, PAND_PORGI ;
DR   B4S4T8, PAND_PROA2 ;  B4EUD1, PAND_PROMH ;  A4SGF2, PAND_PROVI ;
DR   A6VCI7, PAND_PSEA7 ;  B7V1E3, PAND_PSEA8 ;  Q02FU1, PAND_PSEAB ;
DR   Q9HV68, PAND_PSEAE ;  Q848I5, PAND_PSEFL ;  A4VPM8, PAND_PSEU5 ;
DR   Q4FVB6, PAND_PSYA2 ;  Q1QED7, PAND_PSYCK ;  A1SSG7, PAND_PSYIN ;
DR   A5WHA7, PAND_PSYWF ;  A1RUA9, PAND_PYRIL ;  B2UC88, PAND_RALPJ ;
DR   Q8XVU6, PAND_RALSO ;  A9WT19, PAND_RENSM ;  Q7UQU4, PAND_RHOBA ;
DR   B6IPF8, PAND_RHOCS ;  C0ZPL4, PAND_RHOE4 ;  Q21U10, PAND_RHOFD ;
DR   C1BA76, PAND_RHOOB ;  Q0S8D4, PAND_RHOSR ;  A1AXA6, PAND_RUTMC ;
DR   Q21LV5, PAND_SACD2 ;  A4F6T1, PAND_SACEN ;  B5F831, PAND_SALA4 ;
DR   A8M8F2, PAND_SALAI ;  A9MPM3, PAND_SALAR ;  Q57T75, PAND_SALCH ;
DR   B5FIX6, PAND_SALDC ;  B5R3E4, PAND_SALEP ;  B5RHB9, PAND_SALG2 ;
DR   B4TK03, PAND_SALHS ;  B4SUA6, PAND_SALNS ;  Q5PDB9, PAND_SALPA ;
DR   A9MZS9, PAND_SALPB ;  C0Q5P2, PAND_SALPC ;  B5BL63, PAND_SALPK ;
DR   Q2S2P5, PAND_SALRD ;  B4TXN2, PAND_SALSV ;  P65663, PAND_SALTI ;
DR   A4XCQ3, PAND_SALTO ;  P65662, PAND_SALTY ;  A8GIZ8, PAND_SERP5 ;
DR   B2U2X8, PAND_SHIB3 ;  Q326A6, PAND_SHIBS ;  Q32K78, PAND_SHIDS ;
DR   Q0T870, PAND_SHIF8 ;  P0A793, PAND_SHIFL ;  Q3Z5M9, PAND_SHISS ;
DR   Q2NVR4, PAND_SODGM ;  A9EUF9, PAND_SORC5 ;  A6U4X7, PAND_STAA2 ;
DR   Q2FDR2, PAND_STAA3 ;  Q2FV23, PAND_STAA8 ;  A5IW22, PAND_STAA9 ;
DR   Q2YWG1, PAND_STAAB ;  Q5HCV5, PAND_STAAC ;  A6QK84, PAND_STAAE ;
DR   P65664, PAND_STAAM ;  P65665, PAND_STAAN ;  Q6GDK6, PAND_STAAR ;
DR   Q6G679, PAND_STAAS ;  Q8NUN3, PAND_STAAW ;  B9DKF6, PAND_STACT ;
DR   Q5HL37, PAND_STAEQ ;  Q8CMZ4, PAND_STAES ;  Q4LA33, PAND_STAHJ ;
DR   Q826E8, PAND_STRAW ;  P58286, PAND_STRCO ;  B1VSQ0, PAND_STRGG ;
DR   B4SRY6, PAND_STRM5 ;  B2FL70, PAND_STRMK ;  Q30TR6, PAND_SULDN ;
DR   B2V7Y0, PAND_SULSY ;  Q2LSQ4, PAND_SYNAS ;  A0LF66, PAND_SYNFM ;
DR   Q0B0P4, PAND_SYNWW ;  Q55382, PAND_SYNY3 ;  C5BN52, PAND_TERTT ;
DR   B7IG50, PAND_THEAB ;  Q47NS4, PAND_THEFY ;  A8F5K4, PAND_THELT ;
DR   A6LJQ5, PAND_THEM4 ;  Q9X037, PAND_THEMA ;  A5INN0, PAND_THEP1 ;
DR   B0KC92, PAND_THEP3 ;  B0K363, PAND_THEPX ;  B1L8P0, PAND_THESQ ;
DR   Q72L22, PAND_THET2 ;  Q5SKN7, PAND_THET8 ;  Q31FF9, PAND_THICR ;
DR   Q3SH81, PAND_THIDA ;  B8GNA7, PAND_THISH ;  C4L931, PAND_TOLAT ;
DR   Q118E6, PAND_TRIEI ;  A5CW02, PAND_VESOH ;  O34246, PAND_WOLSU ;
DR   Q8PLK9, PAND_XANAC ;  Q3BUL4, PAND_XANC5 ;  Q4UTV7, PAND_XANC8 ;
DR   B0RTT9, PAND_XANCB ;  Q8P9S8, PAND_XANCP ;  Q2P379, PAND_XANOM ;
DR   Q5H0A6, PAND_XANOR ;  A7IHU0, PAND_XANP2 ;  Q9PGR7, PAND_XYLFA ;
DR   B0U1Q4, PAND_XYLFM ;  Q87EV8, PAND_XYLFT ;  A1JJN6, PAND_YERE8 ;
DR   A7FM24, PAND_YERP3 ;  Q1C3V6, PAND_YERPA ;  B2K532, PAND_YERPB ;
DR   Q8ZBK6, PAND_YERPE ;  A9R1G4, PAND_YERPG ;  Q1CLW2, PAND_YERPN ;
DR   A4TPV3, PAND_YERPP ;  Q66EG5, PAND_YERPS ;  B1JK37, PAND_YERPY ;
//
ID   4.1.1.12
DE   Aspartate 4-decarboxylase.
AN   Desulfinase.
AN   L-aspartate 4-carboxy-lyase.
CA   L-aspartate = L-alanine + CO(2).
CF   Pyridoxal 5'-phosphate.
CC   -!- Also catalyzes the decarboxylation of aminomalonate and the
CC       desulfination of 3-sulfino-L-alanine to sulfite and alanine.
CC   -!- Formerly EC 4.1.1.10.
//
ID   4.1.1.13
DE   Deleted entry.
//
ID   4.1.1.14
DE   Valine decarboxylase.
AN   L-valine carboxy-lyase.
CA   L-valine = 2-methylpropanamine + CO(2).
CF   Pyridoxal 5'-phosphate.
CC   -!- Also acts on L-leucine.
//
ID   4.1.1.15
DE   Glutamate decarboxylase.
AN   L-glutamate 1-carboxy-lyase.
CA   L-glutamate = 4-aminobutanoate + CO(2).
CF   Pyridoxal 5'-phosphate.
CC   -!- The brain enzyme also acts on L-cysteate, 3-sulfino-L-alanine and
CC       L-aspartate.
PR   PROSITE; PDOC00329;
DR   Q42521, DCE1_ARATH ;  Q0VCA1, DCE1_BOVIN ;  A0PA85, DCE1_CANFA ;
DR   P14748, DCE1_FELCA ;  Q99259, DCE1_HUMAN ;  P48318, DCE1_MOUSE ;
DR   Q5IS68, DCE1_PANTR ;  P48319, DCE1_PIG   ;  Q5R7S7, DCE1_PONAB ;
DR   P18088, DCE1_RAT   ;  Q42472, DCE2_ARATH ;  Q4PRC2, DCE2_CANFA ;
DR   Q05329, DCE2_HUMAN ;  P48320, DCE2_MOUSE ;  P48321, DCE2_PIG   ;
DR   Q05683, DCE2_RAT   ;  P58228, DCEA_ECO57 ;  P69909, DCEA_ECOL6 ;
DR   P69908, DCEA_ECOLI ;  Q9F5P3, DCEA_LISMO ;  Q83PR1, DCEA_SHIFL ;
DR   P69911, DCEB_ECO57 ;  Q8FHG5, DCEB_ECOL6 ;  P69910, DCEB_ECOLI ;
DR   Q928R9, DCEB_LISIN ;  Q9EYW9, DCEB_LISMO ;  P69912, DCEB_SHIFL ;
DR   Q928K4, DCEC_LISIN ;  Q8Y4K4, DCEC_LISMO ;  P20228, DCE_DROME  ;
DR   Q9CG20, DCE_LACLA  ;  O30418, DCE_LACLM  ;  Q07346, DCE_PETHY  ;
DR   P54767, DCE_SOLLC  ;  Q04792, DCE_YEAST  ;  Q54VQ5, GADA_DICDI ;
DR   Q54IJ3, GADB_DICDI ;  Q9QY94, GLNA_ACOCA ;  P15103, GLNA_BOVIN ;
DR   Q8HZM5, GLNA_CANFA ;  P16580, GLNA_CHICK ;  P04773, GLNA_CRIGR ;
DR   P15104, GLNA_HUMAN ;  Q4R7U3, GLNA_MACFA ;  P15105, GLNA_MOUSE ;
DR   P46410, GLNA_PIG   ;  P09606, GLNA_RAT   ;  P51121, GLNA_XENLA ;
//
ID   4.1.1.16
DE   Hydroxyglutamate decarboxylase.
AN   3-hydroxy-L-glutamate 1-carboxy-lyase.
CA   3-hydroxy-L-glutamate = 4-amino-3-hydroxybutanoate + CO(2).
CF   Pyridoxal 5'-phosphate.
//
ID   4.1.1.17
DE   Ornithine decarboxylase.
AN   L-ornithine carboxy-lyase.
CA   L-ornithine = putrescine + CO(2).
CF   Pyridoxal 5'-phosphate.
PR   PROSITE; PDOC00585;
PR   PROSITE; PDOC00685;
DR   O50657, DCLO_SELRU ;  P40807, DCOR1_DROME;  P27120, DCOR1_XENLA;
DR   P40808, DCOR2_DROME;  Q9I8S4, DCOR2_XENLA;  P27117, DCOR_BOVIN ;
DR   P41931, DCOR_CAEEL ;  P78599, DCOR_CANAL ;  Q8S3N2, DCOR_CAPAN ;
DR   P27118, DCOR_CHICK ;  P14019, DCOR_CRIGR ;  P50134, DCOR_DATST ;
DR   Q54UF3, DCOR_DICDI ;  P21169, DCOR_ECOLI ;  P44317, DCOR_HAEIN ;
DR   P11926, DCOR_HUMAN ;  P43099, DCOR_LACS3 ;  P27116, DCOR_LEIDO ;
DR   P00860, DCOR_MOUSE ;  P27119, DCOR_MUSPA ;  P27121, DCOR_NEUCR ;
DR   P49725, DCOR_PANRE ;  Q92445, DCOR_PARBR ;  P09057, DCOR_RAT   ;
DR   Q9UQW9, DCOR_SCHPO ;  O22616, DCOR_SOLLC ;  P07805, DCOR_TRYBB ;
DR   P08432, DCOR_YEAST ;  P24169, DCOS_ECOLI ;
//
ID   4.1.1.18
DE   Lysine decarboxylase.
AN   L-lysine carboxy-lyase.
CA   L-lysine = cadaverine + CO(2).
CF   Pyridoxal 5'-phosphate.
CC   -!- Also acts on 5'-hydroxy-L-lysine.
PR   PROSITE; PDOC00585;
DR   O50657, DCLO_SELRU ;  P05033, DCLY_HAFAL ;  P52095, DCLZ_ECOLI ;
DR   P0A9H4, LDCI_ECO57 ;  P0A9H3, LDCI_ECOLI ;  P0A1Z1, LDCI_SALTI ;
DR   P0A1Z0, LDCI_SALTY ;
//
ID   4.1.1.19
DE   Arginine decarboxylase.
AN   L-arginine carboxy-lyase.
CA   L-arginine = agmatine + CO(2).
CF   Pyridoxal 5'-phosphate.
PR   PROSITE; PDOC00585;
PR   PROSITE; PDOC00685;
DR   Q5L5E7, AAXB_CHLAB ;  Q822F3, AAXB_CHLCV ;  Q255I0, AAXB_CHLFF ;
DR   Q9PK21, AAXB_CHLMU ;  Q9Z6M7, AAXB_CHLPN ;  P0C8R4, AAXB_CHLT2 ;
DR   Q3KLY3, AAXB_CHLTA ;  P0C8R5, AAXB_CHLTB ;  O84378, AAXB_CHLTR ;
DR   Q7XRA1, ADC2_ORYSJ ;  Q96A70, ADC_HUMAN  ;  P28629, ADIA_ECOLI ;
DR   Q9YG22, ARGDC_AERPE;  A8MBV3, ARGDC_CALMQ;  A2BM05, ARGDC_HYPBU;
DR   A8AAB6, ARGDC_IGNH4;  A4YH98, ARGDC_METS5;  Q8ZWK3, ARGDC_PYRAE;
DR   A4WIW6, ARGDC_PYRAR;  A3MTU5, ARGDC_PYRCJ;  A1RV83, ARGDC_PYRIL;
DR   A3DLU8, ARGDC_STAMF;  Q4J932, ARGDC_SULAC;  C3N6F7, ARGDC_SULIA;
DR   C4KHX2, ARGDC_SULIK;  C3MQN7, ARGDC_SULIL;  C3MWN7, ARGDC_SULIM;
DR   C3NGS9, ARGDC_SULIN;  C3NEW5, ARGDC_SULIY;  Q9UWU1, ARGDC_SULSO;
DR   Q971K9, ARGDC_SULTO;  B1YD10, ARGDC_THENV;  O27983, PDAD1_ARCFU;
DR   Q8TLM4, PDAD1_METAC;  P58889, PDAD1_METMA;  O30240, PDAD2_ARCFU;
DR   Q8TKB4, PDAD2_METAC;  P58890, PDAD2_METMA;  B3EGI2, PDAD_CHLL2 ;
DR   B3QM53, PDAD_CHLP8 ;  B3ELD9, PDAD_CHLPB ;  B3QWJ5, PDAD_CHLT3 ;
DR   Q8KEX0, PDAD_CHLTE ;  B0R6U7, PDAD_HALS3 ;  Q9HNQ0, PDAD_HALSA ;
DR   A6UUL7, PDAD_META3 ;  Q12UX3, PDAD_METBU ;  Q57764, PDAD_METJA ;
DR   Q8TXD4, PDAD_METKA ;  A4G0Z0, PDAD_METM5 ;  A9A979, PDAD_METM6 ;
DR   A6VHH0, PDAD_METM7 ;  Q6LWX2, PDAD_METMP ;  O26956, PDAD_METTH ;
DR   A6UQM7, PDAD_METVS ;  A9A5S1, PDAD_NITMS ;  Q3B5D1, PDAD_PELLD ;
DR   Q6KZS5, PDAD_PICTO ;  B4S6J7, PDAD_PROA2 ;  A4SFG2, PDAD_PROVI ;
DR   Q9V173, PDAD_PYRAB ;  Q8U0G6, PDAD_PYRFU ;  O59240, PDAD_PYRHO ;
DR   Q5JFI4, PDAD_PYRKO ;  Q9HK30, PDAD_THEAC ;  C6A2R5, PDAD_THESM ;
DR   Q97AN7, PDAD_THEVO ;  Q0W1C7, PDAD_UNCMA ;  Q9SI64, SPE1_ARATH ;
DR   P22220, SPE1_AVESA ;  O82475, SPE1_BRAJU ;  Q96412, SPE1_DIACA ;
DR   Q9SNN0, SPE1_ORYSJ ;  Q43075, SPE1_PEA   ;  P49726, SPE1_SOLLC ;
DR   Q39827, SPE1_SOYBN ;  O23141, SPE2_ARATH ;  O81160, SPE2_THECC ;
DR   P74576, SPEA1_SYNY3;  P72587, SPEA2_SYNY3;  A0KIP8, SPEA_AERHH ;
DR   A4SPD6, SPEA_AERS4 ;  Q0ACK8, SPEA_ALHEH ;  Q81MS2, SPEA_BACAN ;
DR   Q819L4, SPEA_BACCR ;  Q5LIQ3, SPEA_BACFN ;  Q64ZT8, SPEA_BACFR ;
DR   Q9K9K5, SPEA_BACHD ;  P21885, SPEA_BACSU ;  Q8A2B1, SPEA_BACTN ;
DR   A6L012, SPEA_BACV8 ;  Q7NU27, SPEA_CHRVO ;  Q9RXR4, SPEA_DEIRA ;
DR   Q8XCX9, SPEA_ECO57 ;  B5YQD6, SPEA_ECO5E ;  Q8FE34, SPEA_ECOL6 ;
DR   P21170, SPEA_ECOLI ;  B1LDE8, SPEA_ECOSM ;  B5EIW4, SPEA_GEOBB ;
DR   B3EAF3, SPEA_GEOLS ;  Q39X78, SPEA_GEOMG ;  B9M6H6, SPEA_GEOSF ;
DR   A0A4W3, SPEA_GEOSL ;  C6E3V4, SPEA_GEOSM ;  A5GB52, SPEA_GEOUR ;
DR   Q7NE10, SPEA_GLOVI ;  C4K6F4, SPEA_HAMD5 ;  B5XUB1, SPEA_KLEP3 ;
DR   A1TY02, SPEA_MARAV ;  Q9JT25, SPEA_NEIMA ;  Q9K0U3, SPEA_NEIMB ;
DR   Q8YRP3, SPEA_NOSS1 ;  Q9CL60, SPEA_PASMU ;  A1AS90, SPEA_PELPD ;
DR   Q7N121, SPEA_PHOLL ;  A3PA96, SPEA_PROM0 ;  A8G243, SPEA_PROM2 ;
DR   A2CDK1, SPEA_PROM3 ;  A2BU00, SPEA_PROM5 ;  Q31DD8, SPEA_PROM9 ;
DR   Q7VEG4, SPEA_PROMA ;  B4F1A4, SPEA_PROMH ;  Q7TUJ9, SPEA_PROMM ;
DR   Q7V3M9, SPEA_PROMP ;  A2BNH3, SPEA_PROMS ;  Q9HUX1, SPEA_PSEAE ;
DR   Q88QC7, SPEA_PSEPK ;  Q87VU3, SPEA_PSESM ;  Q7UTS2, SPEA_RHOBA ;
DR   B5F5L1, SPEA_SALA4 ;  Q57K30, SPEA_SALCH ;  B5FUJ7, SPEA_SALDC ;
DR   B4THH1, SPEA_SALHS ;  B4T5J3, SPEA_SALNS ;  A9N4N1, SPEA_SALPB ;
DR   B4TV55, SPEA_SALSV ;  P60658, SPEA_SALTI ;  P60659, SPEA_SALTY ;
DR   A1S712, SPEA_SHEAM ;  B8EAI2, SPEA_SHEB2 ;  A3D3G2, SPEA_SHEB5 ;
DR   A6WM65, SPEA_SHEB8 ;  A9KY70, SPEA_SHEB9 ;  Q12LW6, SPEA_SHEDO ;
DR   Q083L6, SPEA_SHEFN ;  B0TQX3, SPEA_SHEHH ;  A3QDD8, SPEA_SHELP ;
DR   Q8EFU5, SPEA_SHEON ;  A8H5G3, SPEA_SHEPA ;  A4Y5Y9, SPEA_SHEPC ;
DR   B8CR70, SPEA_SHEPW ;  A0KVN8, SPEA_SHESA ;  A8FWJ3, SPEA_SHESH ;
DR   Q0HJY2, SPEA_SHESM ;  Q0HW78, SPEA_SHESR ;  A1RKK8, SPEA_SHESW ;
DR   B1KRD4, SPEA_SHEWM ;  Q0T0V3, SPEA_SHIF8 ;  Q83Q93, SPEA_SHIFL ;
DR   Q7U3S0, SPEA_SYNPX ;  A5GWM2, SPEA_SYNR3 ;  Q8DHY6, SPEA_THEEB ;
DR   C4L9A9, SPEA_TOLAT ;  Q9KLD1, SPEA_VIBCH ;  Q87JS8, SPEA_VIBPA ;
DR   Q8DA54, SPEA_VIBVU ;  Q7MK24, SPEA_VIBVY ;  Q8PFQ5, SPEA_XANAC ;
DR   Q8P448, SPEA_XANCP ;  B2I6M1, SPEA_XYLF2 ;  Q9PH02, SPEA_XYLFA ;
DR   B0U1H6, SPEA_XYLFM ;  Q87F25, SPEA_XYLFT ;  Q8ZHG8, SPEA_YERPE ;
//
ID   4.1.1.20
DE   Diaminopimelate decarboxylase.
AN   DAP decarboxylase.
AN   Meso-2,6-diaminoheptanedioate carboxy-lyase.
CA   Meso-2,6-diaminoheptanedioate = L-lysine + CO(2).
CF   Pyridoxal 5'-phosphate.
PR   PROSITE; PDOC00685;
DR   Q949X7, DCDA1_ARATH;  P56129, DCDA1_HELPY;  Q94A94, DCDA2_ARATH;
DR   B4XMC6, DCDA2_HELPY;  O69203, DCDA_ACTPA ;  O67262, DCDA_AQUAE ;
DR   O29458, DCDA_ARCFU ;  Q9KCM5, DCDA_BACHD ;  P41023, DCDA_BACMT ;
DR   P23630, DCDA_BACSU ;  Q8A800, DCDA_BACTN ;  P57513, DCDA_BUCAI ;
DR   Q8K9C4, DCDA_BUCAP ;  Q89AC6, DCDA_BUCBP ;  Q9PII5, DCDA_CAMJE ;
DR   Q8RQM6, DCDA_COREF ;  P09890, DCDA_CORGL ;  Q9RTK2, DCDA_DEIRA ;
DR   P00861, DCDA_ECOLI ;  E0IWI3, DCDA_ECOLW ;  Q2A5D5, DCDA_FRATH ;
DR   P44316, DCDA_HAEIN ;  Q9ZME5, DCDA_HELPJ ;  Q58497, DCDA_METJA ;
DR   O27390, DCDA_METTH ;  P0A5M5, DCDA_MYCBO ;  Q50140, DCDA_MYCLE ;
DR   Q9X5M1, DCDA_MYCS2 ;  P0A5M4, DCDA_MYCTU ;  Q9JWA6, DCDA_NEIMA ;
DR   Q9JXM2, DCDA_NEIMB ;  Q6ZG77, DCDA_ORYSJ ;  P19572, DCDA_PSEAE ;
DR   O05321, DCDA_PSEFL ;  Q5HG20, DCDA_STAAC ;  Q9ZBH5, DCDA_STRCO ;
DR   Q55484, DCDA_SYNY3 ;  Q9HK20, DCDA_THEAC ;  Q9X1K5, DCDA_THEMA ;
DR   Q9KVL7, DCDA_VIBCH ;  Q9Z661, DCDA_ZYMMO ;
//
ID   4.1.1.21
DE   Phosphoribosylaminoimidazole carboxylase.
AN   1-(5-phosphoribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase.
AN   5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase.
AN   5-amino-1-ribosylimidazole 5-phosphate carboxylase.
AN   5-phosphoribosyl-5-aminoimidazole carboxylase.
AN   AIR carboxylase.
CA   5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate = 5-amino-1-
CA   (5-phospho-D-ribosyl)imidazole + CO(2).
CC   -!- While this is the reaction that occurs in vertebrates during purine
CC       biosynthesis, two enzymes are required to carry out the same reaction
CC       in Escherichia coli, namely EC 6.3.4.18 and EC 5.4.99.18.
CC   -!- 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole is not a substrate.
PR   PROSITE; PDOC50975;
DR   Q10457, PUR6_CAEEL ;  Q92210, PUR6_CANAL ;  O74197, PUR6_CANGA ;
DR   P38024, PUR6_CHICK ;  P0CQ37, PUR6_CRYNB ;  P0CQ36, PUR6_CRYNJ ;
DR   P0C017, PUR6_CRYNV ;  Q9I7S8, PUR6_DROME ;  P22234, PUR6_HUMAN ;
DR   Q9DCL9, PUR6_MOUSE ;  Q01930, PUR6_PICME ;  Q5RB59, PUR6_PONAB ;
DR   P51583, PUR6_RAT   ;  P50504, PUR6_SCHOC ;  P15567, PUR6_SCHPO ;
DR   P55195, PUR6_VIGAC ;  P21264, PUR6_YEAST ;  Q54QE4, PURCE_DICDI;
//
ID   4.1.1.22
DE   Histidine decarboxylase.
AN   L-histidine carboxy-lyase.
CA   L-histidine = histamine + CO(2).
CF   Pyruvate or pyridoxal 5'-phosphate.
PR   PROSITE; PDOC00329;
DR   B7GZJ8, DCHS_ACIB3 ;  B7I459, DCHS_ACIB5 ;  B2HVG6, DCHS_ACIBC ;
DR   A3M7A4, DCHS_ACIBT ;  B0VBU8, DCHS_ACIBY ;  Q5EA83, DCHS_BOVIN ;
DR   Q0TU55, DCHS_CLOP1 ;  P0C2E5, DCHS_CLOPE ;  Q05733, DCHS_DROME ;
DR   P28577, DCHS_ENTAE ;  P19113, DCHS_HUMAN ;  Q8L0Z4, DCHS_KLEOR ;
DR   P04193, DCHS_LACBU ;  P00862, DCHS_LACS3 ;  P00863, DCHS_MICSP ;
DR   P05034, DCHS_MORMO ;  P23738, DCHS_MOUSE ;  Q1IAK7, DCHS_PSEE4 ;
DR   P95477, DCHS_PSEFL ;  P28578, DCHS_RAOPL ;  P16453, DCHS_RAT   ;
DR   Q98A07, DCHS_RHILO ;  P54772, DCHS_SOLLC ;  Q56581, DCHS_VIBAN ;
DR   A7MVI6, DCHS_VIBHB ;
//
ID   4.1.1.23
DE   Orotidine-5'-phosphate decarboxylase.
AN   OMP decarboxylase.
AN   OMPdcase.
AN   Orotidine-5'-phosphate carboxy-lyase.
AN   Orotidylic decarboxylase.
AN   UMP synthase.
AN   Uridine 5'-monophosphate synthase.
CA   Orotidine 5'-phosphate = UMP + CO(2).
CC   -!- The enzyme from higher eukaryotes is identical with EC 2.4.2.10.
PR   PROSITE; PDOC00141;
DR   Q8YSY4, PYRFE_NOSS1;  A1TW93, PYRF_ACIAC ;  Q6F9Z3, PYRF_ACIAD ;
DR   B7H3K6, PYRF_ACIB3 ;  B7I534, PYRF_ACIB5 ;  B2HZE8, PYRF_ACIBC ;
DR   B0VN04, PYRF_ACIBS ;  A3M508, PYRF_ACIBT ;  B0VD17, PYRF_ACIBY ;
DR   A3N0A0, PYRF_ACTP2 ;  B3GXH2, PYRF_ACTP7 ;  B0BP16, PYRF_ACTPJ ;
DR   A6VPK5, PYRF_ACTSZ ;  Q9Y9D9, PYRF_AERPE ;  B9J7M8, PYRF_AGRRK ;
DR   P58638, PYRF_AGRT5 ;  B9JZC0, PYRF_AGRVS ;  Q0VNQ9, PYRF_ALCBS ;
DR   Q0AA48, PYRF_ALHEH ;  B6EIY4, PYRF_ALISL ;  B8J9L8, PYRF_ANAD2 ;
DR   Q2IGK0, PYRF_ANADE ;  Q5PB36, PYRF_ANAMM ;  B4UGH8, PYRF_ANASK ;
DR   B9MS23, PYRF_ANATD ;  Q3MEN8, PYRF_ANAVT ;  O67520, PYRF_AQUAE ;
DR   O29333, PYRF_ARCFU ;  Q5P5M2, PYRF_AROAE ;  Q757S1, PYRF_ASHGO ;
DR   Q5J2D0, PYRF_ASPAW ;  O13410, PYRF_ASPFU ;  Q96WP7, PYRF_ASPKA ;
DR   P07817, PYRF_ASPNG ;  O13416, PYRF_ASPOR ;  Q9P8X9, PYRF_AURPU ;
DR   A1KBR9, PYRF_AZOSB ;  C3P653, PYRF_BACAA ;  C3L743, PYRF_BACAC ;
DR   Q81WF5, PYRF_BACAN ;  B7JJX0, PYRF_BACC0 ;  Q732I6, PYRF_BACC1 ;
DR   B7IUP3, PYRF_BACC2 ;  C1EPP7, PYRF_BACC3 ;  B7H6L9, PYRF_BACC4 ;
DR   B7HLL7, PYRF_BACC7 ;  P46535, PYRF_BACCL ;  A7GRK8, PYRF_BACCN ;
DR   B9IVW0, PYRF_BACCQ ;  Q819S6, PYRF_BACCR ;  Q636E3, PYRF_BACCZ ;
DR   Q5LH12, PYRF_BACFN ;  Q64XW6, PYRF_BACFR ;  Q9K9W2, PYRF_BACHD ;
DR   Q6HET1, PYRF_BACHK ;  Q65JU4, PYRF_BACLD ;  A8FD20, PYRF_BACP2 ;
DR   Q5WFJ5, PYRF_BACSK ;  P25971, PYRF_BACSU ;  Q8A012, PYRF_BACTN ;
DR   A6KWL1, PYRF_BACV8 ;  A9VTC3, PYRF_BACWK ;  Q44843, PYRF_BARBA ;
DR   Q1LTG7, PYRF_BAUCH ;  Q2KY06, PYRF_BORA1 ;  Q7WNS8, PYRF_BORBR ;
DR   Q7W138, PYRF_BORPA ;  A9I6E7, PYRF_BORPD ;  Q7VTM9, PYRF_BORPE ;
DR   Q9LCT0, PYRF_BRAJA ;  A5E8J8, PYRF_BRASB ;  A4YJQ1, PYRF_BRASO ;
DR   B2S9C4, PYRF_BRUA1 ;  Q2YQU9, PYRF_BRUA2 ;  Q57AD4, PYRF_BRUAB ;
DR   A9M9W1, PYRF_BRUC2 ;  C0RG13, PYRF_BRUMB ;  Q8YE79, PYRF_BRUME ;
DR   B0CJX7, PYRF_BRUSI ;  Q8FXW9, PYRF_BRUSU ;  B8D963, PYRF_BUCA5 ;
DR   P57358, PYRF_BUCAI ;  Q8K9Q1, PYRF_BUCAP ;  B8D7G7, PYRF_BUCAT ;
DR   Q89AL6, PYRF_BUCBP ;  A4XKT3, PYRF_CALS8 ;  A8Z6D0, PYRF_CAMC1 ;
DR   A7GWZ8, PYRF_CAMC5 ;  A0RQJ5, PYRF_CAMFF ;  A7HZG2, PYRF_CAMHC ;
DR   A8FKG8, PYRF_CAMJ8 ;  A7H4Z6, PYRF_CAMJD ;  Q9PIC1, PYRF_CAMJE ;
DR   A1VYA1, PYRF_CAMJJ ;  Q5HW86, PYRF_CAMJR ;  B9KFP1, PYRF_CAMLR ;
DR   P13649, PYRF_CANAL ;  Q01378, PYRF_CANBO ;  Q9C150, PYRF_CANDC ;
DR   P33283, PYRF_CANGA ;  Q6IUR4, PYRF_CANGY ;  P32430, PYRF_CANMA ;
DR   Q12595, PYRF_CANPA ;  Q9HFN9, PYRF_CANRU ;  O42771, PYRF_CANTR ;
DR   Q3AC06, PYRF_CARHZ ;  B8GXJ5, PYRF_CAUCN ;  Q9ABW5, PYRF_CAUCR ;
DR   B0T410, PYRF_CAUSK ;  B3PDW7, PYRF_CELJU ;  P14017, PYRF_CEPAC ;
DR   Q1QVK2, PYRF_CHRSD ;  Q7NTL2, PYRF_CHRVO ;  Q9HFV8, PYRF_CLAFU ;
DR   Q97FS5, PYRF_CLOAB ;  A7FYI9, PYRF_CLOB1 ;  C3KU84, PYRF_CLOB6 ;
DR   A5I6W8, PYRF_CLOBH ;  C1FLB3, PYRF_CLOBJ ;  B1INE4, PYRF_CLOBK ;
DR   A7GIH9, PYRF_CLOBL ;  B1L1E4, PYRF_CLOBM ;  A5N2L5, PYRF_CLOK5 ;
DR   A0Q2N3, PYRF_CLONN ;  Q0TRB0, PYRF_CLOP1 ;  Q8XL62, PYRF_CLOPE ;
DR   Q0STN6, PYRF_CLOPS ;  Q891J1, PYRF_CLOTE ;  Q1E9A1, PYRF_COCIM ;
DR   Q4VWW3, PYRF_COCPS ;  Q482F9, PYRF_COLP3 ;  Q8FT43, PYRF_COREF ;
DR   A4QEI3, PYRF_CORGB ;  Q8NQ40, PYRF_CORGL ;  B6J887, PYRF_COXB1 ;
DR   B6J1D4, PYRF_COXB2 ;  A9KCT0, PYRF_COXBN ;  A9NC23, PYRF_COXBR ;
DR   Q83E06, PYRF_COXBU ;  Q0K6Y9, PYRF_CUPNH ;  B3R6U7, PYRF_CUPTR ;
DR   B7KL53, PYRF_CYAP7 ;  P79075, PYRF_CYBFA ;  O94127, PYRF_CYBJA ;
DR   Q6BY69, PYRF_DEBHA ;  Q47AF2, PYRF_DECAR ;  Q3ZAI1, PYRF_DEHE1 ;
DR   A5FP84, PYRF_DEHSB ;  Q3ZWB0, PYRF_DEHSC ;  Q9RSC5, PYRF_DEIRA ;
DR   A9BS60, PYRF_DELAS ;  C6BZZ8, PYRF_DESAD ;  Q30XT2, PYRF_DESDG ;
DR   A8ZWP0, PYRF_DESOH ;  Q72DM8, PYRF_DESVH ;  B8DKC9, PYRF_DESVM ;
DR   A1VF83, PYRF_DESVV ;  A5EVH6, PYRF_DICNV ;  B5YFH2, PYRF_DICT6 ;
DR   B8E2K1, PYRF_DICTD ;  Q12604, PYRF_DIPMG ;  A7ZLA2, PYRF_ECO24 ;
DR   B7UR89, PYRF_ECO27 ;  B7MLV7, PYRF_ECO45 ;  B7L4B7, PYRF_ECO55 ;
DR   P58640, PYRF_ECO57 ;  B7NVQ5, PYRF_ECO7I ;  B7MUC3, PYRF_ECO81 ;
DR   B7LY40, PYRF_ECO8A ;  C4ZTX6, PYRF_ECOBW ;  B1XBN2, PYRF_ECODH ;
DR   A7ZZM0, PYRF_ECOHS ;  Q0TI84, PYRF_ECOL5 ;  Q8FHU2, PYRF_ECOL6 ;
DR   B1ITH3, PYRF_ECOLC ;  P08244, PYRF_ECOLI ;  B7N497, PYRF_ECOLU ;
DR   B6I9Z7, PYRF_ECOSE ;  B1LH07, PYRF_ECOSM ;  Q1RC84, PYRF_ECOUT ;
DR   Q3YSH4, PYRF_EHRCJ ;  Q2GG43, PYRF_EHRCR ;  P10652, PYRF_EMENI ;
DR   A4WAY2, PYRF_ENT38 ;  Q834E3, PYRF_ENTFA ;  Q6D5T3, PYRF_ERWCT ;
DR   Q2N9N4, PYRF_ERYLH ;  B7LRZ7, PYRF_ESCF3 ;  B0S1A1, PYRF_FINM2 ;
DR   A5FHG4, PYRF_FLAJ1 ;  Q2J838, PYRF_FRASC ;  Q8RG83, PYRF_FUSNN ;
DR   B5EIT8, PYRF_GEOBB ;  Q5L0U0, PYRF_GEOKA ;  B3E1T2, PYRF_GEOLS ;
DR   Q39VY5, PYRF_GEOMG ;  B9LZK2, PYRF_GEOSF ;  Q74D58, PYRF_GEOSL ;
DR   C6E497, PYRF_GEOSM ;  C5D8Q3, PYRF_GEOSW ;  A4IM36, PYRF_GEOTN ;
DR   A5G5A2, PYRF_GEOUR ;  Q7NK22, PYRF_GLOVI ;  Q5FNS8, PYRF_GLUOX ;
DR   A0LYL6, PYRF_GRAFK ;  Q7VLR5, PYRF_HAEDU ;  Q4QJV1, PYRF_HAEI8 ;
DR   A5UBN7, PYRF_HAEIE ;  P43812, PYRF_HAEIN ;  B8F472, PYRF_HAEPS ;
DR   Q2SCG0, PYRF_HAHCH ;  A1WUI3, PYRF_HALHL ;  B9LP84, PYRF_HALLT ;
DR   Q5V216, PYRF_HALMA ;  B0R642, PYRF_HALS3 ;  Q9P9M3, PYRF_HALSA ;
DR   P78724, PYRF_HANAN ;  B0TDZ7, PYRF_HELMI ;  B6JPA4, PYRF_HELP2 ;
DR   Q9ZN53, PYRF_HELPJ ;  B2UW09, PYRF_HELPS ;  P56155, PYRF_HELPY ;
DR   A9B3C5, PYRF_HERA2 ;  A4G2V0, PYRF_HERAR ;  Q5QZ42, PYRF_IDILO ;
DR   A6SVJ9, PYRF_JANMA ;  Q28K56, PYRF_JANSC ;  B5XS09, PYRF_KLEP3 ;
DR   P07922, PYRF_KLULA ;  P41769, PYRF_KLUMA ;  P48844, PYRF_KODOH ;
DR   Q5FJB3, PYRF_LACAC ;  Q1G991, PYRF_LACDA ;  Q049E0, PYRF_LACDB ;
DR   Q043A6, PYRF_LACGA ;  Q74J28, PYRF_LACJO ;  Q9CFW9, PYRF_LACLA ;
DR   P50924, PYRF_LACLM ;  Q02YJ4, PYRF_LACLS ;  P77888, PYRF_LACPL ;
DR   Q1WTX2, PYRF_LACS1 ;  Q38X21, PYRF_LACSS ;  C1D549, PYRF_LARHH ;
DR   Q1MRK9, PYRF_LAWIP ;  Q5X5E0, PYRF_LEGPA ;  A5IBR7, PYRF_LEGPC ;
DR   Q5ZVL5, PYRF_LEGPH ;  Q5WWS3, PYRF_LEGPL ;  Q04NB4, PYRF_LEPBJ ;
DR   Q04WJ4, PYRF_LEPBL ;  B1XXP1, PYRF_LEPCP ;  Q8EXA4, PYRF_LEPIN ;
DR   Q92AH6, PYRF_LISIN ;  C1KWD1, PYRF_LISMC ;  Q71YI4, PYRF_LISMF ;
DR   B8DDS0, PYRF_LISMH ;  P58641, PYRF_LISMO ;  A0AJT7, PYRF_LISW6 ;
DR   B1HQC3, PYRF_LYSSC ;  Q2W019, PYRF_MAGSA ;  Q65SI1, PYRF_MANSM ;
DR   A1TZF4, PYRF_MARAV ;  A6W097, PYRF_MARMS ;  Q8TS37, PYRF_METAC ;
DR   Q46GE2, PYRF_METBF ;  Q12X87, PYRF_METBU ;  B7KUF7, PYRF_METC4 ;
DR   Q609Y2, PYRF_METCA ;  A9W2W3, PYRF_METEP ;  B3DVI6, PYRF_METI4 ;
DR   Q57700, PYRF_METJA ;  A9A6C3, PYRF_METM6 ;  Q8PV88, PYRF_METMA ;
DR   Q6LZM2, PYRF_METMP ;  B8IFW8, PYRF_METNO ;  B1ZFB1, PYRF_METPB ;
DR   A2SLY9, PYRF_METPP ;  B1M7M3, PYRF_METRJ ;  B0UL68, PYRF_METS4 ;
DR   Q2NHA5, PYRF_METST ;  Q977X5, PYRF_METTE ;  O26232, PYRF_METTH ;
DR   Q2RK39, PYRF_MOOTA ;  A0QI32, PYRF_MYCA1 ;  P0A5M7, PYRF_MYCBO ;
DR   A1KIH4, PYRF_MYCBP ;  C1AN30, PYRF_MYCBT ;  B8ZUL5, PYRF_MYCLB ;
DR   Q9CCR1, PYRF_MYCLE ;  B2HP45, PYRF_MYCMM ;  Q741H0, PYRF_MYCPA ;
DR   Q8EUY3, PYRF_MYCPE ;  O08323, PYRF_MYCS2 ;  A5U287, PYRF_MYCTA ;
DR   P0A5M6, PYRF_MYCTU ;  A0PPJ3, PYRF_MYCUA ;  A1T8H2, PYRF_MYCVP ;
DR   P24220, PYRF_MYXXD ;  Q3ISC9, PYRF_NATPD ;  B9L788, PYRF_NAUPA ;
DR   Q5F9J2, PYRF_NEIG1 ;  B4RKA3, PYRF_NEIG2 ;  A9M3Q3, PYRF_NEIM0 ;
DR   Q9JV18, PYRF_NEIMA ;  Q9K005, PYRF_NEIMB ;  A1KT74, PYRF_NEIMF ;
DR   P05035, PYRF_NEUCR ;  Q0AIZ1, PYRF_NITEC ;  Q82TD8, PYRF_NITEU ;
DR   Q1QMP2, PYRF_NITHX ;  Q2Y7B1, PYRF_NITMU ;  Q3J8N5, PYRF_NITOC ;
DR   A6Q2C1, PYRF_NITSB ;  Q3SRG9, PYRF_NITWN ;  A1SJF3, PYRF_NOCSJ ;
DR   P58639, PYRF_NOSS1 ;  Q2G8S2, PYRF_NOVAD ;  Q8ER36, PYRF_OCEIH ;
DR   Q04H28, PYRF_OENOB ;  B6JCI7, PYRF_OLICO ;  B1ZSC4, PYRF_OPITP ;
DR   O93864, PYRF_PACTA ;  Q9C131, PYRF_PARBR ;  A6LDS0, PYRF_PARD8 ;
DR   Q9CMM1, PYRF_PASMU ;  C6DK13, PYRF_PECCP ;  Q3A6R4, PYRF_PELCD ;
DR   A1APM0, PYRF_PELPD ;  Q7Z8L4, PYRF_PENCA ;  P09463, PYRF_PENCH ;
DR   Q8J269, PYRF_PENNA ;  A9BJH6, PYRF_PETMO ;  Q7N4C1, PYRF_PHOLL ;
DR   Q6LPE7, PYRF_PHOPR ;  P21593, PYRF_PHYBL ;  Q06375, PYRF_PICAN ;
DR   Q9C1J2, PYRF_PICPA ;  P49434, PYRF_PICST ;  A1VU11, PYRF_POLNA ;
DR   B2RME4, PYRF_PORG3 ;  Q7MXT6, PYRF_PORGI ;  Q6A911, PYRF_PROAC ;
DR   A3PEG2, PYRF_PROM0 ;  A2C4A1, PYRF_PROM1 ;  A8G6D9, PYRF_PROM2 ;
DR   A9BBV1, PYRF_PROM4 ;  A2BY35, PYRF_PROM5 ;  Q319F9, PYRF_PROM9 ;
DR   Q7VAP8, PYRF_PROMA ;  B4EW04, PYRF_PROMH ;  Q7V5Y2, PYRF_PROMM ;
DR   Q7V0D8, PYRF_PROMP ;  A2BSQ0, PYRF_PROMS ;  Q46JD8, PYRF_PROMT ;
DR   Q48KP5, PYRF_PSE14 ;  Q15T09, PYRF_PSEA6 ;  A6V3L5, PYRF_PSEA7 ;
DR   B7V800, PYRF_PSEA8 ;  Q02P38, PYRF_PSEAB ;  Q59654, PYRF_PSEAE ;
DR   Q1ID82, PYRF_PSEE4 ;  Q4KFV3, PYRF_PSEF5 ;  C3K758, PYRF_PSEFS ;
DR   Q3IGA7, PYRF_PSEHT ;  A5W7B0, PYRF_PSEP1 ;  Q3K8H1, PYRF_PSEPF ;
DR   B0KUJ6, PYRF_PSEPG ;  Q88LW2, PYRF_PSEPK ;  B1J5Q0, PYRF_PSEPW ;
DR   Q884R0, PYRF_PSESM ;  Q4ZVD9, PYRF_PSEU2 ;  Q4FRL9, PYRF_PSYA2 ;
DR   Q1QA56, PYRF_PSYCK ;  A1SYZ6, PYRF_PSYIN ;  Q9UZ35, PYRF_PYRAB ;
DR   Q8U1U1, PYRF_PYRFU ;  O58462, PYRF_PYRHO ;  Q5JDB0, PYRF_PYRKO ;
DR   Q1LIV4, PYRF_RALME ;  B2UCD6, PYRF_RALPJ ;  P58642, PYRF_RALSO ;
DR   B3PYJ5, PYRF_RHIE6 ;  Q2KDF0, PYRF_RHIEC ;  Q9EYV3, PYRF_RHIFR ;
DR   Q1MMI1, PYRF_RHIL3 ;  Q98DD5, PYRF_RHILO ;  B5ZYG6, PYRF_RHILW ;
DR   Q92SN8, PYRF_RHIME ;  P43230, PYRF_RHINI ;  Q71HN5, PYRF_RHIOR ;
DR   Q9Y720, PYRF_RHIPU ;  P32431, PYRF_RHIRA ;  Q7UIA4, PYRF_RHOBA ;
DR   Q21RX7, PYRF_RHOFD ;  Q2J316, PYRF_RHOP2 ;  Q07UT0, PYRF_RHOP5 ;
DR   Q6NCY0, PYRF_RHOPA ;  Q21CH8, PYRF_RHOPB ;  Q13E64, PYRF_RHOPS ;
DR   B3Q976, PYRF_RHOPT ;  Q2RNS7, PYRF_RHORT ;  Q3IY00, PYRF_RHOS4 ;
DR   A7NS27, PYRF_ROSCS ;  A5UPS3, PYRF_ROSS1 ;  Q21IS8, PYRF_SACD2 ;
DR   Q9Y726, PYRF_SACEX ;  Q9UVZ5, PYRF_SACFI ;  B5F565, PYRF_SALA4 ;
DR   A8LY20, PYRF_SALAI ;  Q57NV3, PYRF_SALCH ;  B5R486, PYRF_SALEP ;
DR   B5R6P3, PYRF_SALG2 ;  B4T6V0, PYRF_SALNS ;  Q5PD06, PYRF_SALPA ;
DR   B5BID8, PYRF_SALPK ;  P58643, PYRF_SALTI ;  A4X621, PYRF_SALTO ;
DR   P07691, PYRF_SALTY ;  P14964, PYRF_SCHCO ;  P14965, PYRF_SCHPO ;
DR   Q8EEI4, PYRF_SHEON ;  A8FVN0, PYRF_SHESH ;  B2U0H4, PYRF_SHIB3 ;
DR   Q31ZX5, PYRF_SHIBS ;  Q32GQ2, PYRF_SHIDS ;  Q0T5B6, PYRF_SHIF8 ;
DR   Q83RM1, PYRF_SHIFL ;  Q3Z131, PYRF_SHISS ;  Q5LND3, PYRF_SILPO ;
DR   A6UFC6, PYRF_SINMW ;  Q2NT36, PYRF_SODGM ;  Q9HF68, PYRF_SOLCC ;
DR   P78748, PYRF_SORMK ;  Q1GU89, PYRF_SPHAL ;  A7X1F5, PYRF_STAA1 ;
DR   Q2FHN4, PYRF_STAA3 ;  Q2FZ71, PYRF_STAA8 ;  Q2YXG4, PYRF_STAAB ;
DR   Q5HGM8, PYRF_STAAC ;  A6QGA5, PYRF_STAAE ;  P65595, PYRF_STAAM ;
DR   P99145, PYRF_STAAN ;  Q6GHN1, PYRF_STAAR ;  Q6GA09, PYRF_STAAS ;
DR   P65596, PYRF_STAAW ;  Q5HPY7, PYRF_STAEQ ;  Q8CPJ3, PYRF_STAES ;
DR   Q4L5Q6, PYRF_STAHJ ;  Q49WY5, PYRF_STAS1 ;  Q3K145, PYRF_STRA1 ;
DR   Q8E5F0, PYRF_STRA3 ;  Q8DZQ2, PYRF_STRA5 ;  Q9KXR8, PYRF_STRCO ;
DR   C0M7X0, PYRF_STRE4 ;  B4U3E1, PYRF_STREM ;  A8AXM8, PYRF_STRGC ;
DR   B4SRN9, PYRF_STRM5 ;  B2FU58, PYRF_STRMK ;  Q8DTV1, PYRF_STRMU ;
DR   Q9A077, PYRF_STRP1 ;  Q04LJ3, PYRF_STRP2 ;  P0DC80, PYRF_STRP3 ;
DR   B5E301, PYRF_STRP4 ;  Q5XCK8, PYRF_STRP6 ;  C1C651, PYRF_STRP7 ;
DR   Q8P1C0, PYRF_STRP8 ;  Q1JC81, PYRF_STRPB ;  Q1JM65, PYRF_STRPC ;
DR   Q1JHB0, PYRF_STRPD ;  Q1J729, PYRF_STRPF ;  A2RF05, PYRF_STRPG ;
DR   B1IAM6, PYRF_STRPI ;  B8ZMZ9, PYRF_STRPJ ;  Q48U10, PYRF_STRPM ;
DR   P0CB75, PYRF_STRPN ;  P0DC81, PYRF_STRPQ ;  B2IN86, PYRF_STRPS ;
DR   B5XL15, PYRF_STRPZ ;  Q8DQL6, PYRF_STRR6 ;  A4W1D9, PYRF_STRS2 ;
DR   C0ME50, PYRF_STRS7 ;  A3CN89, PYRF_STRSV ;  A4VV36, PYRF_STRSY ;
DR   Q5LZW9, PYRF_STRT1 ;  Q5M4I0, PYRF_STRT2 ;  Q03KS6, PYRF_STRTD ;
DR   B9DUH9, PYRF_STRU0 ;  C1CD54, PYRF_STRZJ ;  C1CJF5, PYRF_STRZP ;
DR   C1CQG7, PYRF_STRZT ;  Q30QK7, PYRF_SULDN ;  A6Q826, PYRF_SULNB ;
DR   Q9UX10, PYRF_SULSO ;  B2V790, PYRF_SULSY ;  Q970X0, PYRF_SULTO ;
DR   Q2LQ82, PYRF_SYNAS ;  Q31K20, PYRF_SYNE7 ;  Q2JTW6, PYRF_SYNJA ;
DR   Q2JPF1, PYRF_SYNJB ;  Q5N1T9, PYRF_SYNP6 ;  A5GN53, PYRF_SYNPW ;
DR   Q7U8P3, PYRF_SYNPX ;  Q0I824, PYRF_SYNS3 ;  Q3AZD9, PYRF_SYNS9 ;
DR   Q3AHU2, PYRF_SYNSC ;  Q0AXG7, PYRF_SYNWW ;  P73761, PYRF_SYNY3 ;
DR   C5BSJ7, PYRF_TERTT ;  O74110, PYRF_THEAC ;  Q8DLT3, PYRF_THEEB ;
DR   Q47R19, PYRF_THEFY ;  Q9WYG7, PYRF_THEMA ;  B0KA34, PYRF_THEP3 ;
DR   B0K2E7, PYRF_THEPX ;  B9L1A9, PYRF_THERP ;  P96076, PYRF_THET2 ;
DR   P58883, PYRF_THETN ;  Q97CS3, PYRF_THEVO ;  Q31GC7, PYRF_THICR ;
DR   Q3SK77, PYRF_THIDA ;  C4LEZ7, PYRF_TOLAT ;  Q8J0E6, PYRF_TORDE ;
DR   Q12709, PYRF_TRIAT ;  Q119B9, PYRF_TRIEI ;  P21594, PYRF_TRIRE ;
DR   P15188, PYRF_USTMA ;  C5CQB2, PYRF_VARPS ;  A1WGU4, PYRF_VEREI ;
DR   A5F6Y1, PYRF_VIBC3 ;  Q9KQT7, PYRF_VIBCH ;  C3LNL5, PYRF_VIBCM ;
DR   Q5E3Z6, PYRF_VIBF1 ;  B5FG54, PYRF_VIBFM ;  A7MUN7, PYRF_VIBHB ;
DR   Q87N49, PYRF_VIBPA ;  B7VH29, PYRF_VIBSL ;  Q8D8J6, PYRF_VIBVU ;
DR   Q7MLX2, PYRF_VIBVY ;  Q8D2J1, PYRF_WIGBR ;  B3CN77, PYRF_WOLPP ;
DR   Q7MAE8, PYRF_WOLSU ;  Q5GRJ9, PYRF_WOLTR ;  Q8PER4, PYRF_XANAC ;
DR   Q3BMA4, PYRF_XANC5 ;  Q4UNV9, PYRF_XANC8 ;  B0RZ30, PYRF_XANCB ;
DR   Q8P3D7, PYRF_XANCP ;  Q2P8Z6, PYRF_XANOM ;  B2SHJ1, PYRF_XANOP ;
DR   Q5H6B9, PYRF_XANOR ;  B2I656, PYRF_XYLF2 ;  Q9PHB0, PYRF_XYLFA ;
DR   B0U1D6, PYRF_XYLFM ;  Q87FA3, PYRF_XYLFT ;  Q12724, PYRF_YARLI ;
DR   P03962, PYRF_YEAST ;  A1JM26, PYRF_YERE8 ;  A7FI10, PYRF_YERP3 ;
DR   Q1C7L9, PYRF_YERPA ;  B2K4I4, PYRF_YERPB ;  P58644, PYRF_YERPE ;
DR   A9R8T1, PYRF_YERPG ;  Q1CJ05, PYRF_YERPN ;  A4TJ45, PYRF_YERPP ;
DR   Q66AI1, PYRF_YERPS ;  B1JKQ0, PYRF_YERPY ;  Q9HFX0, PYRF_ZYGBA ;
DR   Q42586, UMPS_ARATH ;  P31754, UMPS_BOVIN ;  P09556, UMPS_DICDI ;
DR   Q01637, UMPS_DROME ;  P11172, UMPS_HUMAN ;  P13439, UMPS_MOUSE ;
DR   Q25566, UMPS_NAEGR ;  Q5R514, UMPS_PONAB ;  Q42942, UMPS_TOBAC ;
//
ID   4.1.1.24
DE   Aminobenzoate decarboxylase.
AN   Aminobenzoate carboxy-lyase.
CA   4(or 2)-aminobenzoate = aniline + CO(2).
CF   Pyridoxal 5'-phosphate.
//
ID   4.1.1.25
DE   Tyrosine decarboxylase.
AN   L-tyrosine carboxy-lyase.
CA   L-tyrosine = tyramine + CO(2).
CF   Pyridoxal 5'-phosphate.
CC   -!- The bacterial enzyme also acts on 3-hydroxytyrosine and, more slowly,
CC       on 3-hydroxyphenylalanine.
PR   PROSITE; PDOC00329;
DR   O28275, MFNA_ARCFU ;  Q5V1B4, MFNA_HALMA ;  B0R349, MFNA_HALS3 ;
DR   Q9HSA3, MFNA_HALSA ;  A6UVR4, MFNA_META3 ;  Q8TUQ9, MFNA_METAC ;
DR   A7IAB9, MFNA_METB6 ;  Q46DU3, MFNA_METBF ;  Q12VA2, MFNA_METBU ;
DR   Q2FSD2, MFNA_METHJ ;  Q60358, MFNA_METJA ;  Q8TV92, MFNA_METKA ;
DR   A2STQ3, MFNA_METLZ ;  A4G060, MFNA_METM5 ;  A6VIC0, MFNA_METM7 ;
DR   Q8PXA5, MFNA_METMA ;  A3CWM4, MFNA_METMJ ;  Q6M0Y7, MFNA_METMP ;
DR   B8GDM7, MFNA_METPE ;  A5ULW4, MFNA_METS3 ;  Q2NHY7, MFNA_METST ;
DR   O27188, MFNA_METTH ;  A0B9M9, MFNA_METTP ;  A6URB4, MFNA_METVS ;
DR   Q3IT46, MFNA_NATPD ;  Q9UZD5, MFNA_PYRAB ;  Q8U1P6, MFNA_PYRFU ;
DR   O58679, MFNA_PYRHO ;  Q5JJ82, MFNA_PYRKO ;  C5A2X8, MFNA_THEGJ ;
DR   Q0W498, MFNA_UNCMA ;  Q8RY79, TYDC1_ARATH;  Q7XHL3, TYDC1_ORYSJ;
DR   P54768, TYDC1_PAPSO;  Q06085, TYDC1_PETCR;  Q9M0G4, TYDC2_ARATH;
DR   P54769, TYDC2_PAPSO;  Q06086, TYDC2_PETCR;  P54770, TYDC3_PAPSO;
DR   Q06087, TYDC3_PETCR;  Q06088, TYDC4_PETCR;  P54771, TYDC5_PAPSO;
//
ID   4.1.1.26
DE   Transferred entry: 4.1.1.28.
//
ID   4.1.1.27
DE   Transferred entry: 4.1.1.28.
//
ID   4.1.1.28
DE   Aromatic-L-amino-acid decarboxylase.
AN   5-hydroxytryptophan decarboxylase.
AN   Aromatic amino acid decarboxylase.
AN   DOPA decarboxylase.
AN   Hydroxytryptophan decarboxylase.
AN   L-DOPA decarboxylase.
AN   Tryptophan decarboxylase.
CA   (1) 3,4-dihydroxy-L-phenylalanine = dopamine + CO(2).
CA   (2) 5-hydroxy-L-tryptophan = 5-hydroxytryptamine + CO(2).
CF   Pyridoxal 5'-phosphate.
CC   -!- Also acts on other aromatic L-amino acids, including L-tryptophan.
CC   -!- Formerly EC 4.1.1.26 and EC 4.1.1.27.
PR   PROSITE; PDOC00329;
DR   P27718, DDC_BOVIN  ;  P34751, DDC_CAEEL  ;  P17770, DDC_CATRO  ;
DR   P22781, DDC_CAVPO  ;  O96571, DDC_DROLE  ;  P05031, DDC_DROME  ;
DR   O96567, DDC_DROSI  ;  P20711, DDC_HUMAN  ;  P48861, DDC_MANSE  ;
DR   O88533, DDC_MOUSE  ;  P80041, DDC_PIG    ;  P14173, DDC_RAT    ;
DR   P54768, TYDC1_PAPSO;  P54769, TYDC2_PAPSO;  P54770, TYDC3_PAPSO;
DR   P54771, TYDC5_PAPSO;
//
ID   4.1.1.29
DE   Sulfinoalanine decarboxylase.
AN   3-sulfino-L-alanine carboxy-lyase.
AN   CSADCase.
AN   Cysteine-sulfinate decarboxylase.
AN   Cysteinesulfinic acid decarboxylase.
CA   3-sulfino-L-alanine = hypotaurine + CO(2).
CF   Pyridoxal 5'-phosphate.
CC   -!- Also acts on L-cysteate.
DR   Q9Y600, CSAD_HUMAN ;  Q9DBE0, CSAD_MOUSE ;  Q64611, CSAD_RAT   ;
//
ID   4.1.1.30
DE   Pantothenoylcysteine decarboxylase.
AN   N-((R)-pantothenoyl)-L-cysteine carboxy-lyase.
CA   N-((R)-pantothenoyl)-L-cysteine = pantetheine + CO(2).
//
ID   4.1.1.31
DE   Phosphoenolpyruvate carboxylase.
AN   PEP carboxylase.
AN   PEPCase.
AN   Phosphoenolpyruvic carboxylase.
CA   Phosphate + oxaloacetate = H(2)O + phosphoenolpyruvate + HCO(3)(-).
CC   -!- This enzyme replenishes oxaloacetate in the tricarboxylic acid cycle
CC       when operating in the reverse direction.
CC   -!- The reaction proceeds in two steps: formation of carboxyphosphate and
CC       the enolate form of pyruvate, followed by carboxylation of the
CC       enolate and release of phosphate.
PR   PROSITE; PDOC00330;
DR   Q9MAH0, CAPP1_ARATH;  P81831, CAPP1_CHLRE;  Q01647, CAPP1_FLAPR;
DR   P04711, CAPP1_MAIZE;  P10490, CAPP1_MESCR;  P29193, CAPP1_SACHY;
DR   P29195, CAPP1_SORBI;  Q02909, CAPP1_SOYBN;  Q5GM68, CAPP2_ARATH;
DR   Q6R2V6, CAPP2_CHLRE;  P51059, CAPP2_MAIZE;  P16097, CAPP2_MESCR;
DR   P29194, CAPP2_SORBI;  P51061, CAPP2_SOYBN;  Q84VW9, CAPP3_ARATH;
DR   P15804, CAPP3_SORBI;  Q8GVE8, CAPP4_ARATH;  O28786, CAPPA_ARCFU;
DR   A8MBK0, CAPPA_CALMQ;  Q0TRE4, CAPPA_CLOP1;  Q8XLE8, CAPPA_CLOPE;
DR   Q0STS8, CAPPA_CLOPS;  P30694, CAPPA_FLATR;  B0R7F9, CAPPA_HALS3;
DR   Q9HN43, CAPPA_HALSA;  Q03VI7, CAPPA_LEUMM;  Q8TMG9, CAPPA_METAC;
DR   Q469A3, CAPPA_METBF;  Q2FLH1, CAPPA_METHJ;  Q8TYV1, CAPPA_METKA;
DR   Q8PS70, CAPPA_METMA;  A4YES9, CAPPA_METS5;  O27026, CAPPA_METTH;
DR   Q04D35, CAPPA_OENOB;  Q6L0F3, CAPPA_PICTO;  Q9V2Q9, CAPPA_PYRAB;
DR   Q8ZT64, CAPPA_PYRAE;  A4WJM7, CAPPA_PYRAR;  A3MVZ5, CAPPA_PYRCJ;
DR   Q8TZL5, CAPPA_PYRFU;  O57764, CAPPA_PYRHO;  A1RR50, CAPPA_PYRIL;
DR   Q4JCJ1, CAPPA_SULAC;  C3N0D7, CAPPA_SULIA;  C4KJI5, CAPPA_SULIK;
DR   C3MJE5, CAPPA_SULIL;  C3MTS7, CAPPA_SULIM;  C3NJA0, CAPPA_SULIN;
DR   C3N8C3, CAPPA_SULIY;  Q97WG4, CAPPA_SULSO;  Q96YS2, CAPPA_SULTO;
DR   A1RZN3, CAPPA_THEPD;  Q9FV66, CAPPB_FLATR;  Q9FV65, CAPPC_FLATR;
DR   Q6F6Q6, CAPP_ACIAD ;  A3MA94, CAPP_ACIBT ;  A3MZ57, CAPP_ACTP2 ;
DR   A0KFU8, CAPP_AERHH ;  A4SIM0, CAPP_AERS4 ;  Q0VRS0, CAPP_ALCBS ;
DR   B6EMN4, CAPP_ALISL ;  Q43299, CAPP_AMAHP ;  Q3MB82, CAPP_ANAVT ;
DR   Q5P7H5, CAPP_AROAE ;  A1R2V3, CAPP_ARTAT ;  A8I060, CAPP_AZOC5 ;
DR   A1K454, CAPP_AZOSB ;  Q7WQB3, CAPP_BORBR ;  Q7WCA9, CAPP_BORPA ;
DR   Q7W0D0, CAPP_BORPE ;  Q89R17, CAPP_BRAJA ;  A3MLK7, CAPP_BURM7 ;
DR   A2SAH4, CAPP_BURM9 ;  Q62LC1, CAPP_BURMA ;  A1V5U2, CAPP_BURMS ;
DR   A3N6Z8, CAPP_BURP6 ;  Q63W75, CAPP_BURPS ;  A4JGV5, CAPP_BURVG ;
DR   Q143B6, CAPP_BURXL ;  Q9A871, CAPP_CAUCR ;  Q1QX15, CAPP_CHRSD ;
DR   Q7P206, CAPP_CHRVO ;  A8AKW6, CAPP_CITK8 ;  Q93MH3, CAPP_CORCT ;
DR   P61448, CAPP_CORDI ;  Q8RQL3, CAPP_COREF ;  P12880, CAPP_CORGL ;
DR   A7ZUH4, CAPP_ECO24 ;  B7UNT2, CAPP_ECO27 ;  B7MI92, CAPP_ECO45 ;
DR   B7LA56, CAPP_ECO55 ;  Q8X743, CAPP_ECO57 ;  B5Z058, CAPP_ECO5E ;
DR   B7NU44, CAPP_ECO7I ;  B7MR83, CAPP_ECO81 ;  B7M710, CAPP_ECO8A ;
DR   C5A0C2, CAPP_ECOBW ;  B1XBC1, CAPP_ECODH ;  A8A764, CAPP_ECOHS ;
DR   A1AID4, CAPP_ECOK1 ;  Q0TAA4, CAPP_ECOL5 ;  Q8FB98, CAPP_ECOL6 ;
DR   B1IVC2, CAPP_ECOLC ;  P00864, CAPP_ECOLI ;  B7NFQ6, CAPP_ECOLU ;
DR   B6I5H2, CAPP_ECOSE ;  B1LNR6, CAPP_ECOSM ;  Q1R3V5, CAPP_ECOUT ;
DR   C5BC63, CAPP_EDWI9 ;  A4WG55, CAPP_ENT38 ;  Q6DAR6, CAPP_ERWCT ;
DR   B2VGA2, CAPP_ERWT9 ;  B7LUN9, CAPP_ESCF3 ;  Q7NNJ7, CAPP_GLOVI ;
DR   Q4QL71, CAPP_HAEI8 ;  A5UCN0, CAPP_HAEIE ;  A5UIY9, CAPP_HAEIG ;
DR   P43920, CAPP_HAEIN ;  Q0I371, CAPP_HAES1 ;  B0UUJ3, CAPP_HAES2 ;
DR   Q2SL23, CAPP_HAHCH ;  B5XZ20, CAPP_KLEP3 ;  Q5FK38, CAPP_LACAC ;
DR   Q1GBD4, CAPP_LACDA ;  A8YVD9, CAPP_LACH4 ;  A1U2U4, CAPP_MARAV ;
DR   A6VUQ5, CAPP_MARMS ;  Q02735, CAPP_MEDSA ;  Q49136, CAPP_METEA ;
DR   A0QHY0, CAPP_MYCA1 ;  P46710, CAPP_MYCLE ;  P61449, CAPP_MYCPA ;
DR   A0QWX4, CAPP_MYCS2 ;  A0PPN8, CAPP_MYCUA ;  Q5F5A9, CAPP_NEIG1 ;
DR   Q9JWH1, CAPP_NEIMA ;  Q9JXG5, CAPP_NEIMB ;  A1KWE0, CAPP_NEIMF ;
DR   Q0AH90, CAPP_NITEC ;  Q82WS3, CAPP_NITEU ;  Q5YYG7, CAPP_NOCFA ;
DR   P28594, CAPP_NOSS1 ;  Q9CN89, CAPP_PASMU ;  P51062, CAPP_PEA   ;
DR   C6DI86, CAPP_PECCP ;  Q9AU12, CAPP_PHAVU ;  Q7MAX5, CAPP_PHOLL ;
DR   Q6LVH1, CAPP_PHOPR ;  P51063, CAPP_PICAB ;  A3PF64, CAPP_PROM0 ;
DR   A8G779, CAPP_PROM2 ;  A2BYV8, CAPP_PROM5 ;  Q318G7, CAPP_PROM9 ;
DR   Q7V9U4, CAPP_PROMA ;  B4F183, CAPP_PROMH ;  Q7V561, CAPP_PROMM ;
DR   Q7UZT0, CAPP_PROMP ;  A2BTF4, CAPP_PROMS ;  Q48F34, CAPP_PSE14 ;
DR   A6V1A0, CAPP_PSEA7 ;  Q9HXV3, CAPP_PSEAE ;  Q1IDV2, CAPP_PSEE4 ;
DR   Q4KHK5, CAPP_PSEF5 ;  Q3IBX6, CAPP_PSEHT ;  A4XXP6, CAPP_PSEMY ;
DR   A5W881, CAPP_PSEP1 ;  Q3KHE4, CAPP_PSEPF ;  B0KS63, CAPP_PSEPG ;
DR   Q88MR4, CAPP_PSEPK ;  Q886R9, CAPP_PSESM ;  Q4ZWV3, CAPP_PSEU2 ;
DR   A4VN44, CAPP_PSEU5 ;  A1SRH8, CAPP_PSYIN ;  Q8XWW2, CAPP_RALSO ;
DR   Q59757, CAPP_RHOMR ;  Q2IU23, CAPP_RHOP2 ;  Q07QP5, CAPP_RHOP5 ;
DR   O32483, CAPP_RHOPA ;  Q218E3, CAPP_RHOPB ;  Q139X8, CAPP_RHOPS ;
DR   A7NLR3, CAPP_ROSCS ;  A9MI14, CAPP_SALAR ;  Q57H97, CAPP_SALCH ;
DR   B5FPX1, CAPP_SALDC ;  B5QXQ1, CAPP_SALEP ;  B5RF49, CAPP_SALG2 ;
DR   B4TCQ2, CAPP_SALHS ;  B4T0W7, CAPP_SALNS ;  Q5PK55, CAPP_SALPA ;
DR   A9N0G6, CAPP_SALPB ;  C0Q472, CAPP_SALPC ;  B5BJN0, CAPP_SALPK ;
DR   B4TQH2, CAPP_SALSV ;  Q8Z307, CAPP_SALTI ;  Q8ZKM0, CAPP_SALTY ;
DR   A8GL86, CAPP_SERP5 ;  B0TL90, CAPP_SHEHH ;  A3Q9C4, CAPP_SHELP ;
DR   Q8EK30, CAPP_SHEON ;  A8GZ16, CAPP_SHEPA ;  A8G1A9, CAPP_SHESH ;
DR   B2TWF1, CAPP_SHIB3 ;  Q31U32, CAPP_SHIBS ;  Q32AB9, CAPP_SHIDS ;
DR   Q0SY38, CAPP_SHIF8 ;  Q83IS7, CAPP_SHIFL ;  Q3YV20, CAPP_SHISS ;
DR   P29196, CAPP_SOLTU ;  Q3K1U6, CAPP_STRA1 ;  Q8E647, CAPP_STRA3 ;
DR   Q8E0H2, CAPP_STRA5 ;  Q82HE3, CAPP_STRAW ;  Q9RNU9, CAPP_STRCO ;
DR   A8AW99, CAPP_STRGC ;  Q8DV10, CAPP_STRMU ;  Q9A0U7, CAPP_STRP1 ;
DR   Q04KL8, CAPP_STRP2 ;  P0DC98, CAPP_STRP3 ;  Q5XD52, CAPP_STRP6 ;
DR   Q8P1W7, CAPP_STRP8 ;  A2RFQ7, CAPP_STRPG ;  Q97QX6, CAPP_STRPN ;
DR   P0DC99, CAPP_STRPQ ;  Q8DPW5, CAPP_STRR6 ;  A4VZZ0, CAPP_STRS2 ;
DR   A3CP10, CAPP_STRSV ;  A4VTQ4, CAPP_STRSY ;  Q5M0E6, CAPP_STRT1 ;
DR   Q5M4Z3, CAPP_STRT2 ;  Q03LA9, CAPP_STRTD ;  P06516, CAPP_SYNP6 ;
DR   A5GIW5, CAPP_SYNPW ;  Q7U4M0, CAPP_SYNPX ;  P74299, CAPP_SYNY3 ;
DR   P0A3X5, CAPP_THEEB ;  P51060, CAPP_THES7 ;  Q72L05, CAPP_THET2 ;
DR   Q5SKL7, CAPP_THET8 ;  P0A3X6, CAPP_THEVL ;  P27154, CAPP_TOBAC ;
DR   C4L7S3, CAPP_TOLAT ;  A1WGR0, CAPP_VEREI ;  Q9KNT4, CAPP_VIBCH ;
DR   Q5E2E3, CAPP_VIBF1 ;  B5FBP8, CAPP_VIBFM ;  Q87L54, CAPP_VIBPA ;
DR   B7VLL5, CAPP_VIBSL ;  Q8DCN2, CAPP_VIBVU ;  Q7MH68, CAPP_VIBVY ;
DR   Q8PP82, CAPP_XANAC ;  Q3BXC4, CAPP_XANC5 ;  Q4UR00, CAPP_XANC8 ;
DR   Q8P336, CAPP_XANCP ;  Q2NZE4, CAPP_XANOM ;  Q5GW71, CAPP_XANOR ;
DR   A1JI20, CAPP_YERE8 ;  A7FCZ7, CAPP_YERP3 ;  Q1CBV8, CAPP_YERPA ;
DR   B2JZD9, CAPP_YERPB ;  Q8ZA84, CAPP_YERPE ;  Q1CNQ7, CAPP_YERPN ;
DR   A4TRH7, CAPP_YERPP ;  Q66G74, CAPP_YERPS ;  B1JQ63, CAPP_YERPY ;
//
ID   4.1.1.32
DE   Phosphoenolpyruvate carboxykinase (GTP).
AN   PEP carboxykinase.
AN   PEPCK.
AN   Phosphoenolpyruvate carboxykinase.
AN   Phosphoenolpyruvate carboxylase.
AN   Phosphopyruvate carboxylase.
CA   GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO(2).
CC   -!- ITP can act as phosphate donor.
PR   PROSITE; PDOC00421;
DR   Q8HYZ4, PCKGC_BOVIN;  P05153, PCKGC_CHICK;  P35558, PCKGC_HUMAN;
DR   Q9Z2V4, PCKGC_MOUSE;  Q5R5J1, PCKGC_PONAB;  P07379, PCKGC_RAT  ;
DR   P21642, PCKGM_CHICK;  Q869Z4, PCKGM_DICDI;  Q16822, PCKGM_HUMAN;
DR   Q8BH04, PCKGM_MOUSE;  Q6F8P2, PCKG_ACIAD ;  B7GY31, PCKG_ACIB3 ;
DR   B7I624, PCKG_ACIB5 ;  B2HXC1, PCKG_ACIBC ;  B0VSN6, PCKG_ACIBS ;
DR   A3M840, PCKG_ACIBT ;  B0VDR1, PCKG_ACIBY ;  B8J7G1, PCKG_ANAD2 ;
DR   Q2IFT1, PCKG_ANADE ;  B4UDY7, PCKG_ANASK ;  Q5P2P8, PCKG_AROAE ;
DR   A1R317, PCKG_ARTAT ;  A0JSP6, PCKG_ARTS2 ;  Q05893, PCKG_ASCSU ;
DR   Q2L1L0, PCKG_BORA1 ;  Q7WJQ9, PCKG_BORBR ;  Q7WAK8, PCKG_BORPA ;
DR   Q62FI7, PCKG_BURMA ;  B2JJT8, PCKG_BURP8 ;  Q63VB7, PCKG_BURPS ;
DR   Q5L4X1, PCKG_CHLAB ;  Q821M4, PCKG_CHLCV ;  Q256B8, PCKG_CHLFF ;
DR   Q08262, PCKG_CHLLI ;  Q9PLL6, PCKG_CHLMU ;  Q9Z755, PCKG_CHLPN ;
DR   Q8KAD1, PCKG_CHLTE ;  O84716, PCKG_CHLTR ;  A3DJE3, PCKG_CLOTH ;
DR   Q6NET5, PCKG_CORDI ;  Q8FM16, PCKG_COREF ;  A4QHQ4, PCKG_CORGB ;
DR   Q9AEM1, PCKG_CORGL ;  Q4JY04, PCKG_CORJK ;  C4LGT5, PCKG_CORK4 ;
DR   P20007, PCKG_DROME ;  P80525, PCKG_FASHE ;  Q0RCJ7, PCKG_FRAAA ;
DR   Q2J645, PCKG_FRASC ;  A8L175, PCKG_FRASN ;  Q746Y3, PCKG_GEOSL ;
DR   P29190, PCKG_HAECO ;  Q6AGS4, PCKG_LEIXX ;  P65687, PCKG_MYCBO ;
DR   A1KF31, PCKG_MYCBP ;  C1AJN6, PCKG_MYCBT ;  A4T3S1, PCKG_MYCGI ;
DR   B8ZTI5, PCKG_MYCLB ;  O06084, PCKG_MYCLE ;  B2HMX9, PCKG_MYCMM ;
DR   Q73TS2, PCKG_MYCPA ;  A0QP32, PCKG_MYCS2 ;  A3PSV1, PCKG_MYCSJ ;
DR   A1U995, PCKG_MYCSK ;  Q9AGJ6, PCKG_MYCSM ;  Q1BFN7, PCKG_MYCSS ;
DR   A5TYT6, PCKG_MYCTA ;  P65686, PCKG_MYCTU ;  A0PMX1, PCKG_MYCUA ;
DR   A1T1K1, PCKG_MYCVP ;  P22130, PCKG_NEOFR ;  Q5YNB0, PCKG_NOCFA ;
DR   Q9UY53, PCKG_PYRAB ;  Q8U410, PCKG_PYRFU ;  O58050, PCKG_PYRHO ;
DR   Q6F494, PCKG_PYRKO ;  B2U804, PCKG_RALPJ ;  Q8Y3G3, PCKG_RALSO ;
DR   A9WL73, PCKG_RENSM ;  C0ZRP8, PCKG_RHOE4 ;  A4FQV7, PCKG_SACEN ;
DR   A8M2V8, PCKG_SALAI ;  A4X388, PCKG_SALTO ;  Q82I71, PCKG_STRAW ;
DR   Q93JL5, PCKG_STRCO ;  Q4J9S8, PCKG_SULAC ;  Q97VS5, PCKG_SULSO ;
DR   Q972S7, PCKG_SULTO ;  Q9HLV2, PCKG_THEAC ;  C6A0S4, PCKG_THESM ;
DR   P58306, PCKG_THEVO ;  O83159, PCKG_TREPA ;  B2S270, PCKG_TREPS ;
//
ID   4.1.1.33
DE   Diphosphomevalonate decarboxylase.
AN   Mevalonate diphosphate decarboxylase.
AN   Mevalonate pyrophosphate decarboxylase.
CA   ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl
CA   diphosphate + CO(2).
DR   Q751D8, MVD1_ASHGO ;  Q0P570, MVD1_BOVIN ;  Q5U403, MVD1_DANRE ;
DR   Q6BY07, MVD1_DEBHA ;  Q54YQ9, MVD1_DICDI ;  P53602, MVD1_HUMAN ;
DR   Q99JF5, MVD1_MOUSE ;  Q62967, MVD1_RAT   ;  O13963, MVD1_SCHPO ;
DR   P32377, MVD1_YEAST ;
//
ID   4.1.1.34
DE   Dehydro-L-gulonate decarboxylase.
AN   3-dehydro-L-gulonate carboxy-lyase.
AN   Keto-L-gulonate decarboxylase.
CA   3-dehydro-L-gulonate = L-xylulose + CO(2).
//
ID   4.1.1.35
DE   UDP-glucuronate decarboxylase.
AN   UDP-D-glucuronate carboxy-lyase.
AN   UDP-glucuronic acid decarboxylase.
CA   UDP-D-glucuronate = UDP-D-xylose + CO(2).
CF   NAD.
DR   Q6GMI9, UXS1_DANRE ;  Q8NBZ7, UXS1_HUMAN ;  Q91XL3, UXS1_MOUSE ;
DR   Q5R885, UXS1_PONAB ;  Q5PQX0, UXS1_RAT   ;  Q6DF08, UXS1_XENTR ;
//
ID   4.1.1.36
DE   Phosphopantothenoylcysteine decarboxylase.
AN   N-((R)-4'-phosphopantothenoyl)-L-cysteine carboxy-lyase.
CA   N-((R)-4'-phosphopantothenoyl)-L-cysteine = pantotheine 4'-phosphate +
CA   CO(2).
CF   FMN.
DR   O35033, COABC_BACSU;  O51752, COABC_BORBU;  P0ABQ1, COABC_ECOL6;
DR   P0ABQ0, COABC_ECOLI;  P44953, COABC_HAEIN;  Q58323, COABC_METJA;
DR   P67734, COABC_MYCBO;  P67733, COABC_MYCTU;  P73881, COABC_SYNY3;
DR   Q9KVD1, COABC_VIBCH;  Q5E8M6, COABC_VIBF1;  Q87T89, COABC_VIBPA;
DR   Q8DDX8, COABC_VIBVU;  Q7MPS9, COABC_VIBVY;  Q54Y51, COAC_DICDI ;
DR   Q96CD2, COAC_HUMAN ;  Q8BZB2, COAC_MOUSE ;  Q54433, COAC_STRMU ;
DR   Q9SWE5, HAL3A_ARATH;  P94063, HAL3B_ARATH;
//
ID   4.1.1.37
DE   Uroporphyrinogen decarboxylase.
AN   Uroporphyrinogen III decarboxylase.
AN   Uroporphyrinogen-III carboxy-lyase.
CA   Uroporphyrinogen III = coproporphyrinogen + 4 CO(2).
CC   -!- Acts on a number of porphyrinogens.
PR   PROSITE; PDOC00705;
DR   Q93ZB6, DCUP1_ARATH;  Q9AXB0, DCUP1_ORYSJ;  O22886, DCUP2_ARATH;
DR   Q10LR9, DCUP2_ORYSJ;  A1TVM0, DCUP_ACIAC ;  Q6F9M1, DCUP_ACIAD ;
DR   B7GZK6, DCUP_ACIB3 ;  B7I451, DCUP_ACIB5 ;  B2HVF8, DCUP_ACIBC ;
DR   Q1ITV2, DCUP_ACIBL ;  B0VUQ9, DCUP_ACIBS ;  A3M795, DCUP_ACIBT ;
DR   B0VBT2, DCUP_ACIBY ;  A0LUP4, DCUP_ACIC1 ;  A5G1D5, DCUP_ACICJ ;
DR   B9MGH2, DCUP_ACIET ;  A1WCJ3, DCUP_ACISJ ;  A3MYI4, DCUP_ACTP2 ;
DR   B3GZV2, DCUP_ACTP7 ;  B0BS17, DCUP_ACTPJ ;  A6VQT2, DCUP_ACTSZ ;
DR   A4SJ51, DCUP_AERS4 ;  Q8UBL6, DCUP_AGRT5 ;  Q0VMC3, DCUP_ALCBS ;
DR   Q0A4Y2, DCUP_ALHEH ;  B6ENB7, DCUP_ALISL ;  Q2IPY2, DCUP_ANADE ;
DR   A7H9E0, DCUP_ANADF ;  Q3MC76, DCUP_ANAVT ;  O66667, DCUP_AQUAE ;
DR   A8EVQ3, DCUP_ARCB4 ;  Q5P4Q4, DCUP_AROAE ;  A0JYN1, DCUP_ARTS2 ;
DR   A1KCN9, DCUP_AZOSB ;  C1DHQ1, DCUP_AZOVD ;  A7Z323, DCUP_BACA2 ;
DR   A0RAS3, DCUP_BACAH ;  Q81U23, DCUP_BACAN ;  B7JDM6, DCUP_BACC0 ;
DR   Q73C99, DCUP_BACC1 ;  B7IKE2, DCUP_BACC2 ;  B7HGF9, DCUP_BACC4 ;
DR   B7HZJ8, DCUP_BACC7 ;  A7GM02, DCUP_BACCN ;  Q81GW6, DCUP_BACCR ;
DR   Q63ES5, DCUP_BACCZ ;  Q9KDL0, DCUP_BACHD ;  Q6HM98, DCUP_BACHK ;
DR   A8FBM5, DCUP_BACP2 ;  P32395, DCUP_BACSU ;  A9VI98, DCUP_BACWK ;
DR   Q7WEN2, DCUP_BORBR ;  Q7W3B3, DCUP_BORPA ;  A9HY51, DCUP_BORPD ;
DR   Q7VU41, DCUP_BORPE ;  Q89SK1, DCUP_BRAJA ;  A5EDY0, DCUP_BRASB ;
DR   A4YPC0, DCUP_BRASO ;  B2S965, DCUP_BRUA1 ;  Q2YR07, DCUP_BRUA2 ;
DR   Q57AJ2, DCUP_BRUAB ;  A9M9E9, DCUP_BRUC2 ;  C0RFV3, DCUP_BRUMB ;
DR   Q8YJT1, DCUP_BRUME ;  A5VT24, DCUP_BRUO2 ;  B0CJG6, DCUP_BRUSI ;
DR   Q8FY24, DCUP_BRUSU ;  B4EEZ3, DCUP_BURCJ ;  A3MQK6, DCUP_BURM7 ;
DR   A2S6J1, DCUP_BURM9 ;  A1V8S5, DCUP_BURMS ;  A3P0Y4, DCUP_BURP0 ;
DR   A3NF35, DCUP_BURP6 ;  B2T7J6, DCUP_BURPP ;  Q63PI5, DCUP_BURPS ;
DR   Q2STF3, DCUP_BURTA ;  A4JA40, DCUP_BURVG ;  Q13SQ6, DCUP_BURXL ;
DR   A7ZEJ7, DCUP_CAMC1 ;  A7GZU8, DCUP_CAMC5 ;  A0RQV9, DCUP_CAMFF ;
DR   A7I2S8, DCUP_CAMHC ;  A8FMU8, DCUP_CAMJ8 ;  A7H2D8, DCUP_CAMJD ;
DR   Q9PN54, DCUP_CAMJE ;  A1W0M7, DCUP_CAMJJ ;  Q5HTL9, DCUP_CAMJR ;
DR   B9KFM9, DCUP_CAMLR ;  Q3AEU3, DCUP_CARHZ ;  B8GW41, DCUP_CAUCN ;
DR   P0CAX3, DCUP_CAUCR ;  B3PDU1, DCUP_CELJU ;  A9WIS6, DCUP_CHLAA ;
DR   Q5L510, DCUP_CHLAB ;  B8G821, DCUP_CHLAD ;  Q3AUB7, DCUP_CHLCH ;
DR   Q821R0, DCUP_CHLCV ;  B3EHV5, DCUP_CHLL2 ;  Q9PLH7, DCUP_CHLMU ;
DR   B3QL69, DCUP_CHLP8 ;  B3EL29, DCUP_CHLPB ;  A1BCW4, DCUP_CHLPD ;
DR   Q9Z716, DCUP_CHLPN ;  B9LKR9, DCUP_CHLSY ;  B0B8X3, DCUP_CHLT2 ;
DR   B3QXB5, DCUP_CHLT3 ;  Q3KKU6, DCUP_CHLTA ;  B0BAK2, DCUP_CHLTB ;
DR   Q8KAW2, DCUP_CHLTE ;  O84752, DCUP_CHLTR ;  Q1R1C8, DCUP_CHRSD ;
DR   Q7NZ00, DCUP_CHRVO ;  A8AKS6, DCUP_CITK8 ;  Q489Q8, DCUP_COLP3 ;
DR   Q6NJJ4, DCUP_CORDI ;  Q8FSD6, DCUP_COREF ;  A4QB76, DCUP_CORGB ;
DR   Q8NT75, DCUP_CORGL ;  B6J5G8, DCUP_COXB1 ;  B6J229, DCUP_COXB2 ;
DR   A9KCZ5, DCUP_COXBN ;  A9NB09, DCUP_COXBR ;  Q83EP0, DCUP_COXBU ;
DR   Q0K5N1, DCUP_CUPNH ;  Q46VY4, DCUP_CUPPJ ;  B1WVY1, DCUP_CYAA5 ;
DR   B7KKW4, DCUP_CYAP7 ;  Q11X05, DCUP_CYTH3 ;  Q9PTS2, DCUP_DANRE ;
DR   Q47K40, DCUP_DECAR ;  Q9RV96, DCUP_DEIRA ;  A9BPZ7, DCUP_DELAS ;
DR   Q6ANR5, DCUP_DESPS ;  Q54DF9, DCUP_DICDI ;  A5EX29, DCUP_DICNV ;
DR   A8LIJ7, DCUP_DINSH ;  Q9V595, DCUP_DROME ;  O18601, DCUP_DROVI ;
DR   A7ZUL3, DCUP_ECO24 ;  B7UPF2, DCUP_ECO27 ;  B7MIY3, DCUP_ECO45 ;
DR   B7LA91, DCUP_ECO55 ;  Q8X6X5, DCUP_ECO57 ;  B5Z093, DCUP_ECO5E ;
DR   B7NRT0, DCUP_ECO7I ;  B7N2J9, DCUP_ECO81 ;  B7M7Q6, DCUP_ECO8A ;
DR   C5A0T8, DCUP_ECOBW ;  B1XC00, DCUP_ECODH ;  A8A797, DCUP_ECOHS ;
DR   A1AIG8, DCUP_ECOK1 ;  Q0TA68, DCUP_ECOL5 ;  Q8FB74, DCUP_ECOL6 ;
DR   B1IUQ0, DCUP_ECOLC ;  P29680, DCUP_ECOLI ;  B7NFT8, DCUP_ECOLU ;
DR   B6I5K8, DCUP_ECOSE ;  B1LNU9, DCUP_ECOSM ;  Q1R5W3, DCUP_ECOUT ;
DR   C5BHE8, DCUP_EDWI9 ;  A4W5C0, DCUP_ENT38 ;  A7MJ78, DCUP_ENTS8 ;
DR   Q6DAL7, DCUP_ERWCT ;  B2VG77, DCUP_ERWT9 ;  Q2N6J8, DCUP_ERYLH ;
DR   B7LUK5, DCUP_ESCF3 ;  A5FLE7, DCUP_FLAJ1 ;  A6GVN8, DCUP_FLAPJ ;
DR   B0TWR0, DCUP_FRAP2 ;  Q2JDD1, DCUP_FRASC ;  Q14K23, DCUP_FRAT1 ;
DR   A7NEJ1, DCUP_FRATF ;  Q2A1G5, DCUP_FRATH ;  B2SEW4, DCUP_FRATM ;
DR   A0Q8F6, DCUP_FRATN ;  Q0BK67, DCUP_FRATO ;  Q5NIM0, DCUP_FRATT ;
DR   A4IW07, DCUP_FRATW ;  B5E7R1, DCUP_GEOBB ;  Q5L284, DCUP_GEOKA ;
DR   B3EAR8, DCUP_GEOLS ;  Q39ZQ8, DCUP_GEOMG ;  B9M7T4, DCUP_GEOSF ;
DR   Q746R5, DCUP_GEOSL ;  C6E7R9, DCUP_GEOSM ;  C5D6M5, DCUP_GEOSW ;
DR   A4IKU7, DCUP_GEOTN ;  A5GDW7, DCUP_GEOUR ;  Q7NEK2, DCUP_GLOVI ;
DR   A9HDX7, DCUP_GLUDA ;  Q5FS38, DCUP_GLUOX ;  Q0BWA2, DCUP_GRABC ;
DR   A0M6C4, DCUP_GRAFK ;  Q0I5E2, DCUP_HAES1 ;  B0US07, DCUP_HAES2 ;
DR   Q2S9R0, DCUP_HAHCH ;  A1WVX2, DCUP_HALHL ;  C4K8F9, DCUP_HAMD5 ;
DR   Q17W45, DCUP_HELAH ;  Q7VF06, DCUP_HELHP ;  B6JLI7, DCUP_HELP2 ;
DR   B5Z6X6, DCUP_HELPG ;  Q1CTS0, DCUP_HELPH ;  Q9ZLM8, DCUP_HELPJ ;
DR   B2UTM1, DCUP_HELPS ;  O25325, DCUP_HELPY ;  A4GAF0, DCUP_HERAR ;
DR   Q42855, DCUP_HORVU ;  P06132, DCUP_HUMAN ;  B4U9S4, DCUP_HYDS0 ;
DR   Q0BWA4, DCUP_HYPNA ;  Q5QVW3, DCUP_IDILO ;  A6T450, DCUP_JANMA ;
DR   Q28KJ9, DCUP_JANSC ;  B5XYE1, DCUP_KLEP3 ;  A6TGQ4, DCUP_KLEP7 ;
DR   Q5X3M4, DCUP_LEGPA ;  A5IDL1, DCUP_LEGPC ;  Q5ZTY0, DCUP_LEGPH ;
DR   Q5WV12, DCUP_LEGPL ;  Q6AHF5, DCUP_LEIXX ;  Q929G1, DCUP_LISIN ;
DR   C1KXG7, DCUP_LISMC ;  Q71XF3, DCUP_LISMF ;  B8DF98, DCUP_LISMH ;
DR   Q8Y564, DCUP_LISMO ;  A0AKW5, DCUP_LISW6 ;  Q2VYH1, DCUP_MAGSA ;
DR   A0L3L1, DCUP_MAGSM ;  O81220, DCUP_MAIZE ;  Q65W70, DCUP_MANSM ;
DR   A1TYW3, DCUP_MARAV ;  Q0AKD9, DCUP_MARMM ;  Q11CM8, DCUP_MESSB ;
DR   Q60BY1, DCUP_METCA ;  Q1GXV8, DCUP_METFK ;  A2SC07, DCUP_METPP ;
DR   B0JL12, DCUP_MICAN ;  P70697, DCUP_MOUSE ;  A0QIL2, DCUP_MYCA1 ;
DR   Q7TY47, DCUP_MYCBO ;  A1KM16, DCUP_MYCBP ;  C1AFD7, DCUP_MYCBT ;
DR   A4TCS1, DCUP_MYCGI ;  B8ZQX2, DCUP_MYCLB ;  P46809, DCUP_MYCLE ;
DR   B2HM23, DCUP_MYCMM ;  Q73W61, DCUP_MYCPA ;  A0QW23, DCUP_MYCS2 ;
DR   A3PYL0, DCUP_MYCSJ ;  A1UF48, DCUP_MYCSK ;  A5U630, DCUP_MYCTA ;
DR   O53231, DCUP_MYCTU ;  A0PT34, DCUP_MYCUA ;  A1T7Z4, DCUP_MYCVP ;
DR   Q1D1F0, DCUP_MYXXD ;  B9L8M1, DCUP_NAUPA ;  Q5F9N1, DCUP_NEIG1 ;
DR   B4RK59, DCUP_NEIG2 ;  A9M3L2, DCUP_NEIM0 ;  Q9JV52, DCUP_NEIMA ;
DR   Q9K041, DCUP_NEIMB ;  A1KT40, DCUP_NEIMF ;  Q2GCG4, DCUP_NEOSM ;
DR   Q0AIF1, DCUP_NITEC ;  Q82X50, DCUP_NITEU ;  Q1QJ95, DCUP_NITHX ;
DR   Q2YB59, DCUP_NITMU ;  Q3J6U6, DCUP_NITOC ;  A6Q291, DCUP_NITSB ;
DR   Q5YTA5, DCUP_NOCFA ;  A1SMY9, DCUP_NOCSJ ;  B2J9R9, DCUP_NOSP7 ;
DR   Q8YQC4, DCUP_NOSS1 ;  Q2GC56, DCUP_NOVAD ;  Q8ERY0, DCUP_OCEIH ;
DR   A6WX72, DCUP_OCHA4 ;  A5CDS4, DCUP_ORITB ;  B3CR66, DCUP_ORITI ;
DR   A1B852, DCUP_PARDP ;  Q6MB12, DCUP_PARUW ;  P57964, DCUP_PASMU ;
DR   C6DHS9, DCUP_PECCP ;  Q3A6H9, DCUP_PELCD ;  Q3B1E7, DCUP_PELLD ;
DR   B4SGD6, DCUP_PELPB ;  A1ALN0, DCUP_PELPD ;  B4RD11, DCUP_PHEZH ;
DR   Q7N960, DCUP_PHOLL ;  Q6LLW6, DCUP_PHOPR ;  Q6KZ54, DCUP_PICTO ;
DR   A1VJ58, DCUP_POLNA ;  Q123Y6, DCUP_POLSJ ;  Q5RDK5, DCUP_PONAB ;
DR   B4S3W2, DCUP_PROA2 ;  A3PBV7, DCUP_PROM0 ;  A2C141, DCUP_PROM1 ;
DR   A8G3U9, DCUP_PROM2 ;  A2CAR8, DCUP_PROM3 ;  A9BAY8, DCUP_PROM4 ;
DR   A2BVP6, DCUP_PROM5 ;  Q31BV1, DCUP_PROM9 ;  Q7VBL3, DCUP_PROMA ;
DR   B4EYT8, DCUP_PROMH ;  Q7V8B4, DCUP_PROMM ;  Q7V2A0, DCUP_PROMP ;
DR   A2BQ64, DCUP_PROMS ;  Q46LW7, DCUP_PROMT ;  A4SGN6, DCUP_PROVI ;
DR   Q48PG2, DCUP_PSE14 ;  Q15ZB1, DCUP_PSEA6 ;  A6VDF5, DCUP_PSEA7 ;
DR   B7V3C7, DCUP_PSEA8 ;  Q02EY3, DCUP_PSEAB ;  P95458, DCUP_PSEAE ;
DR   Q1IGA3, DCUP_PSEE4 ;  Q4KJI4, DCUP_PSEF5 ;  C3KBH3, DCUP_PSEFS ;
DR   Q3IJU2, DCUP_PSEHT ;  A4XPQ6, DCUP_PSEMY ;  A5WAA7, DCUP_PSEP1 ;
DR   Q3KJ97, DCUP_PSEPF ;  B0KN28, DCUP_PSEPG ;  Q88CV6, DCUP_PSEPK ;
DR   B1J2J9, DCUP_PSEPW ;  Q87V23, DCUP_PSESM ;  Q4ZZD8, DCUP_PSEU2 ;
DR   Q4FRK8, DCUP_PSYA2 ;  Q1QA45, DCUP_PSYCK ;  A1SZJ4, DCUP_PSYIN ;
DR   A5WFU9, DCUP_PSYWF ;  Q1LHL3, DCUP_RALME ;  B2UGT5, DCUP_RALPJ ;
DR   Q8XU90, DCUP_RALSO ;  P32362, DCUP_RAT   ;  Q1MA15, DCUP_RHIL3 ;
DR   Q98DY6, DCUP_RHILO ;  C3MB70, DCUP_RHISN ;  P42503, DCUP_RHOCA ;
DR   C0ZYX0, DCUP_RHOE4 ;  Q220I2, DCUP_RHOFD ;  C1B4A1, DCUP_RHOOB ;
DR   Q2ISV3, DCUP_RHOP2 ;  Q07S20, DCUP_RHOP5 ;  Q132J9, DCUP_RHOPS ;
DR   Q2RN85, DCUP_RHORT ;  A3PM71, DCUP_RHOS1 ;  P32920, DCUP_RHOS4 ;
DR   A4WPZ2, DCUP_RHOS5 ;  B9KLM3, DCUP_RHOSK ;  Q0S1F6, DCUP_RHOSR ;
DR   C3PM28, DCUP_RICAE ;  A8GQC1, DCUP_RICAH ;  A8GYD8, DCUP_RICB8 ;
DR   Q1RGK4, DCUP_RICBR ;  A8F0B3, DCUP_RICCK ;  Q92FV3, DCUP_RICCN ;
DR   Q4UJN8, DCUP_RICFE ;  A8F331, DCUP_RICM5 ;  Q9ZC83, DCUP_RICPR ;
DR   C4K2Z1, DCUP_RICPU ;  B0BVQ6, DCUP_RICRO ;  A8GU66, DCUP_RICRS ;
DR   Q68VM8, DCUP_RICTY ;  A7NKU6, DCUP_ROSCS ;  Q16AR3, DCUP_ROSDO ;
DR   A5UU35, DCUP_ROSS1 ;  A1AXS4, DCUP_RUTMC ;  Q21H88, DCUP_SACD2 ;
DR   A4FAS3, DCUP_SACEN ;  B5F1I0, DCUP_SALA4 ;  A9MHD2, DCUP_SALAR ;
DR   Q57H58, DCUP_SALCH ;  B5FQL2, DCUP_SALDC ;  B5QYF2, DCUP_SALEP ;
DR   B5RFI7, DCUP_SALG2 ;  B4TCT6, DCUP_SALHS ;  B4T0Z9, DCUP_SALNS ;
DR   Q5PKA3, DCUP_SALPA ;  A9N0K9, DCUP_SALPB ;  C0Q2S9, DCUP_SALPC ;
DR   B5BJR6, DCUP_SALPK ;  Q2S1W0, DCUP_SALRD ;  B4TQK7, DCUP_SALSV ;
DR   Q8Z329, DCUP_SALTI ;  A4X548, DCUP_SALTO ;  Q9L9I4, DCUP_SALTY ;
DR   Q9USJ5, DCUP_SCHPO ;  A8G8F7, DCUP_SERP5 ;  A1S2J2, DCUP_SHEAM ;
DR   B8E642, DCUP_SHEB2 ;  A3CZN2, DCUP_SHEB5 ;  A6WTA5, DCUP_SHEB8 ;
DR   A9L5A8, DCUP_SHEB9 ;  Q12S16, DCUP_SHEDO ;  Q8HY31, DCUP_SHEEP ;
DR   Q088H1, DCUP_SHEFN ;  B0TR87, DCUP_SHEHH ;  A3QIJ0, DCUP_SHELP ;
DR   Q8EJM8, DCUP_SHEON ;  A8GZL8, DCUP_SHEPA ;  A4YAY4, DCUP_SHEPC ;
DR   B8CTX5, DCUP_SHEPW ;  A0KSA9, DCUP_SHESA ;  A8FQD0, DCUP_SHESH ;
DR   Q0HN48, DCUP_SHESM ;  Q0HQN5, DCUP_SHESR ;  A1RFE3, DCUP_SHESW ;
DR   B1KN91, DCUP_SHEWM ;  B2TWI4, DCUP_SHIB3 ;  Q31U00, DCUP_SHIBS ;
DR   Q32AH0, DCUP_SHIDS ;  Q0SY03, DCUP_SHIF8 ;  Q83PB7, DCUP_SHIFL ;
DR   Q3YUY7, DCUP_SHISS ;  Q5LMB5, DCUP_SILPO ;  Q1GDK6, DCUP_SILST ;
DR   A6UEF2, DCUP_SINMW ;  Q2NWR2, DCUP_SODGM ;  Q01W10, DCUP_SOLUE ;
DR   A9FZW7, DCUP_SORC5 ;  Q1GP74, DCUP_SPHAL ;  A5VA70, DCUP_SPHWW ;
DR   A7X3T8, DCUP_STAA1 ;  A6U2T7, DCUP_STAA2 ;  Q2FFR2, DCUP_STAA3 ;
DR   Q2FXA3, DCUP_STAA8 ;  A5ITZ9, DCUP_STAA9 ;  Q2YU05, DCUP_STAAB ;
DR   Q5HEU2, DCUP_STAAC ;  A6QI15, DCUP_STAAE ;  P67419, DCUP_STAAM ;
DR   P67420, DCUP_STAAN ;  Q6GFM3, DCUP_STAAR ;  Q6G8A2, DCUP_STAAS ;
DR   A8YY02, DCUP_STAAT ;  P67421, DCUP_STAAW ;  B9DN00, DCUP_STACT ;
DR   Q5HNA4, DCUP_STAEQ ;  Q8CNS0, DCUP_STAES ;  Q4L7D8, DCUP_STAHJ ;
DR   Q49YM7, DCUP_STAS1 ;  Q82KY4, DCUP_STRAW ;  O69861, DCUP_STRCO ;
DR   B1VWH6, DCUP_STRGG ;  Q30SW8, DCUP_SULDN ;  A6QAQ4, DCUP_SULNB ;
DR   P16891, DCUP_SYNE7 ;  Q2JX97, DCUP_SYNJA ;  Q2JKH3, DCUP_SYNJB ;
DR   B1XIF6, DCUP_SYNP2 ;  Q5N4W6, DCUP_SYNP6 ;  A5GJR6, DCUP_SYNPW ;
DR   Q7U645, DCUP_SYNPX ;  A5GSG3, DCUP_SYNR3 ;  Q0I8Y1, DCUP_SYNS3 ;
DR   Q3AYE3, DCUP_SYNS9 ;  Q3AKV7, DCUP_SYNSC ;  P54224, DCUP_SYNY3 ;
DR   C5BRJ3, DCUP_TERTT ;  Q9HLB9, DCUP_THEAC ;  Q8DKW0, DCUP_THEEB ;
DR   Q47NN7, DCUP_THEFY ;  Q72L31, DCUP_THET2 ;  Q5SKP2, DCUP_THET8 ;
DR   B5YK82, DCUP_THEYD ;  Q31JF4, DCUP_THICR ;  B8GPU3, DCUP_THISH ;
DR   Q42967, DCUP_TOBAC ;  C4LAY4, DCUP_TOLAT ;  Q114U6, DCUP_TRIEI ;
DR   Q83H92, DCUP_TROW8 ;  Q83FJ0, DCUP_TROWT ;  C5CLI6, DCUP_VARPS ;
DR   A1WDU6, DCUP_VEREI ;  A5CVK5, DCUP_VESOH ;  A5F3N0, DCUP_VIBC3 ;
DR   Q9KV26, DCUP_VIBCH ;  Q5E249, DCUP_VIBF1 ;  B5FC78, DCUP_VIBFM ;
DR   A7N075, DCUP_VIBHB ;  Q87KR0, DCUP_VIBPA ;  Q8DD14, DCUP_VIBVU ;
DR   Q7MGS7, DCUP_VIBVY ;  Q8CWI5, DCUP_WIGBR ;  Q73GC9, DCUP_WOLPM ;
DR   B3CM33, DCUP_WOLPP ;  Q7MAA5, DCUP_WOLSU ;  Q5GTT1, DCUP_WOLTR ;
DR   C0R449, DCUP_WOLWR ;  Q8PI85, DCUP_XANAC ;  Q3BQR9, DCUP_XANC5 ;
DR   Q4UX89, DCUP_XANC8 ;  B0RQC7, DCUP_XANCB ;  Q8P6X1, DCUP_XANCP ;
DR   Q2P6D1, DCUP_XANOM ;  B2SKP7, DCUP_XANOP ;  Q5H3H5, DCUP_XANOR ;
DR   B2I9F9, DCUP_XYLF2 ;  Q9PDP7, DCUP_XYLFA ;  B0U6C5, DCUP_XYLFM ;
DR   Q87DV0, DCUP_XYLFT ;  P32347, DCUP_YEAST ;  A1JIJ1, DCUP_YERE8 ;
DR   A7FNH2, DCUP_YERP3 ;  Q1C1V3, DCUP_YERPA ;  B2K124, DCUP_YERPB ;
DR   Q8ZAQ7, DCUP_YERPE ;  A9R8D5, DCUP_YERPG ;  Q1CN66, DCUP_YERPN ;
DR   A4TS20, DCUP_YERPP ;  Q66FP1, DCUP_YERPS ;  B1JJL0, DCUP_YERPY ;
//
ID   4.1.1.38
DE   Phosphoenolpyruvate carboxykinase (diphosphate).
AN   PEP carboxyphosphotransferase.
AN   Phosphoenolpyruvate carboxykinase (pyrophosphate).
AN   Phosphoenolpyruvate carboxylase.
AN   Phosphopyruvate carboxylase.
CA   Diphosphate + oxaloacetate = phosphate + phosphoenolpyruvate + CO(2).
CC   -!- Also catalyzes the reaction: phosphoenolpyruvate + phosphate =
CC       pyruvate + diphosphate.
//
ID   4.1.1.39
DE   Ribulose-bisphosphate carboxylase.
AN   Carboxydismutase.
AN   D-ribulose 1,5-diphosphate carboxylase.
AN   D-ribulose-1,5-bisphosphate carboxylase.
AN   Diphosphoribulose carboxylase.
AN   Ribulose 1,5-bisphosphate carboxylase.
AN   Ribulose 1,5-bisphosphate carboxylase/oxygenase.
AN   Ribulose 1,5-diphosphate carboxylase.
AN   Ribulose 1,5-diphosphate carboxylase/oxygenase.
AN   Ribulose bisphosphate carboxylase/oxygenase.
AN   Ribulose diphosphate carboxylase.
AN   Ribulose diphosphate carboxylase/oxygenase.
AN   RuBisCO.
AN   RuBP carboxylase.
CA   2 3-phospho-D-glycerate + 2 H(+) = D-ribulose 1,5-bisphosphate + CO(2) +
CA   H(2)O.
CC   -!- Will utilize O(2) instead of CO(2), forming 3-phospho-D-glycerate and
CC       2-phosphoglycolate.
PR   PROSITE; PDOC00142;
DR   B7JB30, RBL1A_ACIF2;  A5E993, RBL1A_BRASB;  A4YNR1, RBL1A_BRASO;
DR   P22849, RBL1A_CHRVI;  Q59458, RBL1A_HYDMR;  A2SFV1, RBL1A_METPP;
DR   Q1QH22, RBL1A_NITHX;  Q3SR45, RBL1A_NITWN;  Q37BZ5, RBL1A_RHOPS;
DR   Q31IK0, RBL1A_THICR;  P0C916, RBL1A_THIFE;  B7JA24, RBL1B_ACIF2;
DR   P22859, RBL1B_ALLVD;  A5EF40, RBL1B_BRASB;  A4YQD3, RBL1B_BRASO;
DR   Q59460, RBL1B_HYDMR;  A2SJJ7, RBL1B_METPP;  Q1QGD4, RBL1B_NITHX;
DR   Q3SNG2, RBL1B_NITWN;  Q37G91, RBL1B_RHOPS;  Q31HD9, RBL1B_THICR;
DR   P0C917, RBL1B_THIFE;  A5EQ63, RBL1C_BRASB;  P0C2C2, RBL1C_CUPNE;
DR   Q0K1E0, RBL1C_CUPNH;  Q1QFS0, RBL1C_NITHX;  P42721, RBL1P_CUPNH;
DR   O85040, RBL1_HALNC ;  P58348, RBL1_RHIME ;  O32740, RBL1_RHOCB ;
DR   Q6N9J0, RBL1_RHOPA ;  A4WW35, RBL1_RHOS5 ;  P27997, RBL1_RHOSH ;
DR   P56889, RBL1_SINMW ;  Q56259, RBL1_THIDA ;  Q9ZHZ1, RBL1_THIK1 ;
DR   Q479W5, RBL2_DECAR ;  Q42813, RBL2_GONPO ;  Q9ZHZ4, RBL2_HALNC ;
DR   Q5ENN5, RBL2_HETTR ;  Q59462, RBL2_HYDMR ;  Q8RTI2, RBL2_MAGMG ;
DR   Q2W3S5, RBL2_MAGSA ;  A1VNQ9, RBL2_POLNA ;  Q6Y9H0, RBL2_PROMN ;
DR   P50922, RBL2_RHOCA ;  D5AUD5, RBL2_RHOCB ;  Q21YM9, RBL2_RHOFD ;
DR   Q2J1J9, RBL2_RHOP2 ;  Q07N61, RBL2_RHOP5 ;  Q6N0W9, RBL2_RHOPA ;
DR   Q213J3, RBL2_RHOPB ;  Q37D32, RBL2_RHOPS ;  B3QB68, RBL2_RHOPT ;
DR   Q2RRP5, RBL2_RHORT ;  P04718, RBL2_RHORU ;  A3PRW6, RBL2_RHOS1 ;
DR   Q3IX55, RBL2_RHOS4 ;  A4WZV1, RBL2_RHOS5 ;  P29278, RBL2_RHOSH ;
DR   B9KTC8, RBL2_RHOSK ;  Q41406, RBL2_SYMSP ;  Q31IK3, RBL2_THICR ;
DR   Q60028, RBL2_THIDA ;  O84917, RBL2_THIK1 ;  O78258, RBL_ABIFI  ;
DR   O78259, RBL_ABIHO  ;  P24671, RBL_ABIMA  ;  O78261, RBL_ABIMR  ;
DR   O78262, RBL_ABISA  ;  O78260, RBL_ABIVE  ;  P93998, RBL_ACAFA  ;
DR   B0CCC1, RBL_ACAM1  ;  P28376, RBL_ACESA  ;  A5FWR1, RBL_ACICJ  ;
DR   A9LYA9, RBL_ACOAM  ;  Q3V526, RBL_ACOCL  ;  P43222, RBL_ACRAU  ;
DR   P28377, RBL_ACTCH  ;  O99000, RBL_ADEOB  ;  P36476, RBL_ADICA  ;
DR   P43223, RBL_ADIPE  ;  P28378, RBL_ADOMO  ;  P25413, RBL_AEGCR  ;
DR   P25414, RBL_AEGTA  ;  Q31827, RBL_AESPA  ;  A4QJC3, RBL_AETCO  ;
DR   A4QJK7, RBL_AETGR  ;  A1EA16, RBL_AGRST  ;  Q07209, RBL_AILAL  ;
DR   Q31655, RBL_AJUCH  ;  Q07281, RBL_AKABI  ;  Q0A4R1, RBL_ALHEH  ;
DR   P34767, RBL_ALIPL  ;  P25826, RBL_ALLPR  ;  Q06021, RBL_ALNIN  ;
DR   P24672, RBL_ALVHS  ;  P16306, RBL_AMAHP  ;  P48682, RBL_AMATR  ;
DR   Q70XZ5, RBL_AMBTC  ;  Q8MD78, RBL_AMOTI  ;  P48683, RBL_ANACO  ;
DR   Q3M674, RBL_ANAVT  ;  Q31674, RBL_ANEME  ;  B0YPN8, RBL_ANEMR  ;
DR   Q31680, RBL_ANGEV  ;  P28258, RBL_ANGLY  ;  Q31795, RBL_ANTFO  ;
DR   P36478, RBL_ANTGA  ;  Q31669, RBL_ANTHE  ;  Q31672, RBL_ANTLU  ;
DR   Q05554, RBL_ANTMA  ;  P43224, RBL_ANTRE  ;  P24624, RBL_ANTSP  ;
DR   Q31859, RBL_ANTVS  ;  P28379, RBL_APHSI  ;  P28380, RBL_APIGR  ;
DR   Q05984, RBL_APOCA  ;  A4QK26, RBL_ARAHI  ;  O03042, RBL_ARATH  ;
DR   O28635, RBL_ARCFU  ;  P25827, RBL_AREDR  ;  Q32668, RBL_ARGFE  ;
DR   P93890, RBL_ARIGL  ;  P43225, RBL_ARTBA  ;  P36479, RBL_ASACA  ;
DR   P36480, RBL_ASCEX  ;  P92445, RBL_ASPEL  ;  Q31809, RBL_ASPLA  ;
DR   P26490, RBL_ASTLO  ;  Q8RU60, RBL_ATRBE  ;  P19160, RBL_ATRPA  ;
DR   P20455, RBL_ATRRS  ;  Q9MTE7, RBL_AVECA  ;  P48684, RBL_AVESA  ;
DR   P51994, RBL_BAMGL  ;  P28381, RBL_BARCA  ;  Q05795, RBL_BARLO  ;
DR   P28382, RBL_BARPR  ;  Q33162, RBL_BARSC  ;  Q37192, RBL_BARSO  ;
DR   A4QKB3, RBL_BARVE  ;  P25828, RBL_BASAL  ;  Q31730, RBL_BAURU  ;
DR   P48685, RBL_BAZTR  ;  O99001, RBL_BEAGR  ;  P28383, RBL_BEGMS  ;
DR   Q31715, RBL_BERBR  ;  P36481, RBL_BERLA  ;  P28384, RBL_BETNI  ;
DR   Q06022, RBL_BETPA  ;  Q06J26, RBL_BIGNA  ;  O19872, RBL_BIXOR  ;
DR   P43226, RBL_BLEOR  ;  Q05985, RBL_BOROF  ;  P36477, RBL_BOTST  ;
DR   Q31886, RBL_BOUGL  ;  B3TN59, RBL_BRADI  ;  Q9ZI34, RBL_BRAJA  ;
DR   P48686, RBL_BRAOL  ;  Q05796, RBL_BRASC  ;  Q31738, RBL_BREMA  ;
DR   P93988, RBL_BROCO  ;  P26958, RBL_BRYMA  ;  P36482, RBL_BUDDA  ;
DR   O19989, RBL_BULAR  ;  P28385, RBL_BURIN  ;  B2JX50, RBL_BURP8  ;
DR   Q13QV1, RBL_BURXL  ;  A6MM44, RBL_BUXMI  ;  P31180, RBL_BUXSE  ;
DR   P28386, RBL_BYBLI  ;  P28387, RBL_BYRCR  ;  Q05797, RBL_CABCA  ;
DR   O63094, RBL_CAJCA  ;  Q31750, RBL_CALCA  ;  P36483, RBL_CALDI  ;
DR   Q7YJW4, RBL_CALFG  ;  Q05986, RBL_CALHE  ;  P28388, RBL_CALPL  ;
DR   P48687, RBL_CALSH  ;  P25829, RBL_CALUS  ;  Q95694, RBL_CAMLE  ;
DR   P31181, RBL_CAMSI  ;  P27063, RBL_CAPAN  ;  Q31951, RBL_CAPBA  ;
DR   A4QKK0, RBL_CAPBU  ;  Q06023, RBL_CARCO  ;  P48688, RBL_CARPA  ;
DR   P48689, RBL_CARTI  ;  P28389, RBL_CASEQ  ;  O20304, RBL_CASFS  ;
DR   P48690, RBL_CASSA  ;  Q33383, RBL_CATSP  ;  Q9GGX6, RBL_CEDAT  ;
DR   P26959, RBL_CEDDE  ;  P28390, RBL_CEPFO  ;  Q33323, RBL_CEPOC  ;
DR   Q05798, RBL_CERDE  ;  P25830, RBL_CERGL  ;  P28391, RBL_CERGU  ;
DR   Q05987, RBL_CERJA  ;  Q8SN66, RBL_CHAGL  ;  Q1ACK0, RBL_CHAVU  ;
DR   P43227, RBL_CHEBI  ;  Q32016, RBL_CHELA  ;  P36484, RBL_CHIAL  ;
DR   Q19V64, RBL_CHLAT  ;  P08211, RBL_CHLMO  ;  P00877, RBL_CHLRE  ;
DR   A6MMD0, RBL_CHLSC  ;  P12466, RBL_CHLVU  ;  P48691, RBL_CHOCR  ;
DR   P48692, RBL_CHRHI  ;  P43228, RBL_CIBBA  ;  P48693, RBL_CICIN  ;
DR   Q09MH0, RBL_CITSI  ;  P28392, RBL_CLAXA  ;  O20346, RBL_CLITE  ;
DR   P48694, RBL_COFAR  ;  P31182, RBL_COLAR  ;  P48695, RBL_COLOB  ;
DR   Q07210, RBL_COLPU  ;  Q05988, RBL_CONTR  ;  Q31948, RBL_CORAT  ;
DR   P28393, RBL_CORCA  ;  Q06024, RBL_CORCO  ;  Q31983, RBL_CORFO  ;
DR   Q33369, RBL_CORKO  ;  P31183, RBL_CORLA  ;  P28394, RBL_CORMY  ;
DR   Q32040, RBL_COROB  ;  Q32042, RBL_COROF  ;  Q32041, RBL_COROL  ;
DR   Q05579, RBL_CORSA  ;  O98883, RBL_COUGU  ;  P28395, RBL_CRAMA  ;
DR   P43229, RBL_CREBI  ;  Q31946, RBL_CRUAN  ;  Q31992, RBL_CRUGL  ;
DR   A4QKT9, RBL_CRUWA  ;  P48696, RBL_CRYJA  ;  P48697, RBL_CUCPE  ;
DR   P27064, RBL_CUCSA  ;  Q32026, RBL_CUNLA  ;  B3RBL8, RBL_CUPTR  ;
DR   A8W3D6, RBL_CUSEX  ;  A7M906, RBL_CUSGR  ;  A8W3J2, RBL_CUSOB  ;
DR   P30401, RBL_CUSRE  ;  Q49CC1, RBL_CUSSA  ;  B1WXH3, RBL_CYAA5  ;
DR   P37393, RBL_CYACA  ;  Q85G81, RBL_CYAME  ;  B8HQS5, RBL_CYAP4  ;
DR   B7K7P3, RBL_CYAP7  ;  P24312, RBL_CYAPA  ;  A6H5I5, RBL_CYCTA  ;
DR   P24673, RBL_CYLSN  ;  P28396, RBL_CYRRA  ;  P28397, RBL_DAPSP  ;
DR   P28398, RBL_DARCA  ;  P48698, RBL_DATST  ;  Q0G9V4, RBL_DAUCA  ;
DR   P48699, RBL_DENCL  ;  Q33406, RBL_DEPGR  ;  O98945, RBL_DETCO  ;
DR   P48700, RBL_DIACA  ;  P48701, RBL_DICAN  ;  P31184, RBL_DICCR  ;
DR   P28399, RBL_DIGPU  ;  P28400, RBL_DILIN  ;  A6MML5, RBL_DIOEL  ;
DR   P28401, RBL_DIOMU  ;  A4QL27, RBL_DRANE  ;  Q06GY9, RBL_DRIGR  ;
DR   P28402, RBL_DRIWI  ;  P28403, RBL_DROBI  ;  P28404, RBL_DROBR  ;
DR   P28405, RBL_DROCA  ;  P28406, RBL_DRODC  ;  P28407, RBL_DROFI  ;
DR   P28408, RBL_DROLU  ;  P28409, RBL_DROPA  ;  P28410, RBL_DROPT  ;
DR   P28411, RBL_DRORE  ;  P28259, RBL_DRYSU  ;  Q2TGZ2, RBL_DUNTE  ;
DR   P24313, RBL_ECTSI  ;  Q4G3F4, RBL_EMIHU  ;  P28412, RBL_EPASP  ;
DR   Q37328, RBL_EPHSI  ;  Q32223, RBL_EPHTW  ;  P48702, RBL_EQUAR  ;
DR   Q33443, RBL_EREMA  ;  P28413, RBL_ERICA  ;  Q33438, RBL_ERYCG  ;
DR   Q49KZ0, RBL_EUCGG  ;  P28414, RBL_EUCLU  ;  P28415, RBL_EUCUL  ;
DR   P48069, RBL_EUGAN  ;  P48070, RBL_EUGGE  ;  P00878, RBL_EUGGR  ;
DR   P48072, RBL_EUGMY  ;  P48073, RBL_EUGPI  ;  P48074, RBL_EUGST  ;
DR   P48075, RBL_EUGVI  ;  P31186, RBL_EUOMA  ;  P69567, RBL_EUPCH  ;
DR   P69568, RBL_EUPDU  ;  P69569, RBL_EUPES  ;  Q05799, RBL_EURFE  ;
DR   Q05989, RBL_EXAAF  ;  Q7GDW5, RBL_FAGEA  ;  P19161, RBL_FLABI  ;
DR   P19162, RBL_FLAPR  ;  Q05990, RBL_FOUSP  ;  P48703, RBL_FRAAN  ;
DR   Q32255, RBL_GALAL  ;  Q32256, RBL_GALAP  ;  Q32271, RBL_GALCO  ;
DR   Q32283, RBL_GALEL  ;  Q32303, RBL_GALLU  ;  Q32345, RBL_GALPA  ;
DR   Q32344, RBL_GALPR  ;  Q32360, RBL_GALSC  ;  P23755, RBL_GALSU  ;
DR   P28416, RBL_GAREL  ;  P28417, RBL_GERGR  ;  P51101, RBL_GERJA  ;
DR   P31188, RBL_GEUBO  ;  P28418, RBL_GEUCH  ;  P48704, RBL_GINBI  ;
DR   P93906, RBL_GLAGU  ;  P48705, RBL_GLEJA  ;  Q7NIM7, RBL_GLOVI  ;
DR   O62970, RBL_GLYEC  ;  A6BM42, RBL_GNEPA  ;  A0ZZ43, RBL_GOSBA  ;
DR   P14958, RBL_GOSHI  ;  Q6B8P0, RBL_GRATL  ;  B2LMK1, RBL_GUIAB  ;
DR   P14957, RBL_GUITH  ;  O98890, RBL_HALCL  ;  A1WVW0, RBL_HALHL  ;
DR   Q33528, RBL_HALRB  ;  P28419, RBL_HAMMO  ;  P28420, RBL_HARGR  ;
DR   P28421, RBL_HEDHE  ;  P45738, RBL_HELAN  ;  P28422, RBL_HELNU  ;
DR   P28423, RBL_HEUMI  ;  P31189, RBL_HIPRI  ;  P05698, RBL_HORVU  ;
DR   P28424, RBL_HUMBA  ;  Q5SCV9, RBL_HUPLU  ;  Q32397, RBL_HYDFO  ;
DR   Q9ZB35, RBL_HYDPS  ;  P28425, RBL_HYDVI  ;  Q9BA49, RBL_HYOLA  ;
DR   P31190, RBL_ICAMA  ;  Q9XPR5, RBL_IDEPO  ;  P31191, RBL_ILEAQ  ;
DR   P31192, RBL_ILECI  ;  P28426, RBL_ILECR  ;  Q07049, RBL_ILEPE  ;
DR   A6MMV2, RBL_ILLOL  ;  P28260, RBL_IPOPU  ;  P92306, RBL_IRIEN  ;
DR   Q37227, RBL_IRIGE  ;  P92463, RBL_ISOTA  ;  Q06RC1, RBL_JASNU  ;
DR   P28427, RBL_JASSU  ;  P28428, RBL_JUSOD  ;  P26960, RBL_KETDA  ;
DR   O98664, RBL_KIGAF  ;  P48706, RBL_LACSA  ;  P69570, RBL_LAROX  ;
DR   Q33584, RBL_LATCL  ;  Q33600, RBL_LAVLA  ;  A9L9A4, RBL_LEMMI  ;
DR   A6YG96, RBL_LEPTE  ;  A4QLB4, RBL_LEPVR  ;  Q05991, RBL_LIGVU  ;
DR   Q01873, RBL_LIQST  ;  P93913, RBL_LIRPL  ;  P30827, RBL_LIRTU  ;
DR   A4QLK2, RBL_LOBMA  ;  P28429, RBL_LOBSP  ;  A8Y9H8, RBL_LOLPR  ;
DR   Q9BBU1, RBL_LOTJA  ;  P69572, RBL_LUPAA  ;  P69573, RBL_LUPAB  ;
DR   P69574, RBL_LUPAE  ;  P92397, RBL_LUPAL  ;  P69575, RBL_LUPAN  ;
DR   P69576, RBL_LUPAR  ;  P69577, RBL_LUPAT  ;  P69578, RBL_LUPAU  ;
DR   P69579, RBL_LUPCO  ;  P92401, RBL_LUPDE  ;  P69580, RBL_LUPDI  ;
DR   P69581, RBL_LUPHI  ;  P69582, RBL_LUPLA  ;  P69583, RBL_LUPLU  ;
DR   P69584, RBL_LUPMC  ;  P92406, RBL_LUPMI  ;  P69585, RBL_LUPMU  ;
DR   P92407, RBL_LUPNA  ;  P69586, RBL_LUPNO  ;  P69587, RBL_LUPPA  ;
DR   P69588, RBL_LUPPE  ;  P69589, RBL_LUPPI  ;  P69590, RBL_LUPPO  ;
DR   P69591, RBL_LUPPR  ;  P30732, RBL_MAGAC  ;  P30828, RBL_MAGLA  ;
DR   P31193, RBL_MAGLI  ;  P30829, RBL_MAGMA  ;  P61293, RBL_MAGTR  ;
DR   P00874, RBL_MAIZE  ;  P31194, RBL_MALDO  ;  B1NWF8, RBL_MANES  ;
DR   P28430, RBL_MANZA  ;  P06292, RBL_MARPO  ;  P48707, RBL_MATST  ;
DR   P04991, RBL_MEDSA  ;  P31195, RBL_MERAN  ;  Q9MUT6, RBL_MESVI  ;
DR   Q8THG2, RBL_METAC  ;  Q46E16, RBL_METBF  ;  Q603Q7, RBL_METCA  ;
DR   B3DVG5, RBL_METI4  ;  Q58632, RBL_METJA  ;  Q8PXG9, RBL_METMA  ;
DR   B0JVL8, RBL_MICAN  ;  P25831, RBL_MIRJA  ;  Q48952, RBL_MOBAS  ;
DR   P25832, RBL_MOLVE  ;  Q33619, RBL_MONDI  ;  P28431, RBL_MORAL  ;
DR   Q09X09, RBL_MORIN  ;  P48708, RBL_MOROL  ;  Q32625, RBL_MORRU  ;
DR   P28432, RBL_MYRCE  ;  O20241, RBL_NANDO  ;  A4QLU1, RBL_NASOF  ;
DR   P28433, RBL_NELCA  ;  Q05800, RBL_NELLU  ;  P31196, RBL_NEMMU  ;
DR   P28434, RBL_NEPAL  ;  Q9T4F2, RBL_NEPOL  ;  P19163, RBL_NEUMU  ;
DR   P19164, RBL_NEUTE  ;  P11421, RBL_NICAC  ;  P48709, RBL_NICDE  ;
DR   P11422, RBL_NICOT  ;  Q32686, RBL_NICPH  ;  Q3C1J4, RBL_NICSY  ;
DR   Q33C26, RBL_NICTO  ;  Q0AHW1, RBL_NITEC  ;  Q82TG6, RBL_NITEU  ;
DR   Q2YB78, RBL_NITMU  ;  Q3JE87, RBL_NITOC  ;  Q8VW94, RBL_NITS1  ;
DR   Q93A90, RBL_NITS4  ;  Q8VQ84, RBL_NITST  ;  Q59613, RBL_NITVU  ;
DR   Q9XD77, RBL_NITWI  ;  Q32699, RBL_NOLSP  ;  B2J8T2, RBL_NOSP7  ;
DR   P00879, RBL_NOSS1  ;  Q32663, RBL_NOTDE  ;  Q32701, RBL_NOTSU  ;
DR   Q05801, RBL_NUPVA  ;  Q6EW71, RBL_NYMAL  ;  Q05802, RBL_NYMOD  ;
DR   P28261, RBL_NYPFR  ;  P28435, RBL_NYSOG  ;  P49520, RBL_ODOSI  ;
DR   B2X1Y2, RBL_OEDCA  ;  B0Z4K9, RBL_OENAR  ;  B0Z4U3, RBL_OENBI  ;
DR   Q9MTP9, RBL_OENEH  ;  B0Z527, RBL_OENGL  ;  B0Z5B1, RBL_OENPA  ;
DR   Q6LBA6, RBL_OLICO  ;  P14959, RBL_OLILU  ;  A4QJU1, RBL_OLIPU  ;
DR   Q20EX7, RBL_OLTVI  ;  P48710, RBL_ONOSE  ;  Q36610, RBL_ONYJA  ;
DR   Q6ENG6, RBL_ORYNI  ;  P0C510, RBL_ORYSA  ;  P0C511, RBL_ORYSI  ;
DR   P0C512, RBL_ORYSJ  ;  P33536, RBL_OSMCI  ;  Q0P3J3, RBL_OSTTA  ;
DR   Q06025, RBL_OSTVI  ;  P28436, RBL_OXADI  ;  Q9XQJ6, RBL_PACAQ  ;
DR   Q68RZ8, RBL_PANGI  ;  O98668, RBL_PANJS  ;  A1B2Q2, RBL_PARDP  ;
DR   P28437, RBL_PARFI  ;  P28438, RBL_PASQU  ;  A5CKB9, RBL_PAUCH  ;
DR   P04717, RBL_PEA    ;  Q32770, RBL_PELAN  ;  P28439, RBL_PELHO  ;
DR   Q32890, RBL_PELRO  ;  P30830, RBL_PERAE  ;  O04435, RBL_PERSE  ;
DR   P04992, RBL_PETHY  ;  Q3BAN4, RBL_PHAAO  ;  Q9TK52, RBL_PHATC  ;
DR   A4GG89, RBL_PHAVU  ;  P31197, RBL_PHECO  ;  P28262, RBL_PHORE  ;
DR   Q32908, RBL_PHOST  ;  P25833, RBL_PHYAM  ;  P34915, RBL_PHYPA  ;
DR   P48711, RBL_PICAB  ;  P24674, RBL_PICPU  ;  P26961, RBL_PICSI  ;
DR   P26962, RBL_PINBA  ;  P28440, RBL_PINCA  ;  P24675, RBL_PINED  ;
DR   Q7GUD0, RBL_PINKO  ;  P26963, RBL_PINKR  ;  P24677, RBL_PINLO  ;
DR   P24678, RBL_PINPI  ;  P81080, RBL_PINPS  ;  P24679, RBL_PINRA  ;
DR   P41621, RBL_PINTH  ;  Q8WKC9, RBL_PINVI  ;  P24676, RBL_PINWA  ;
DR   Q06GQ2, RBL_PIPCE  ;  P28441, RBL_PLAOC  ;  P28442, RBL_PLAVR  ;
DR   Q08051, RBL_PLECA  ;  Q43036, RBL_PLUAU  ;  P24680, RBL_PODGR  ;
DR   P28443, RBL_POLCR  ;  P48712, RBL_POLMU  ;  Q05992, RBL_POLRE  ;
DR   Q9GHP8, RBL_POLSI  ;  Q14FE9, RBL_POPAL  ;  P48713, RBL_POPTM  ;
DR   A4GYR8, RBL_POPTR  ;  Q09119, RBL_PORAE  ;  P50255, RBL_PORCA  ;
DR   Q760S7, RBL_PORDE  ;  Q760R5, RBL_PORHA  ;  Q760R9, RBL_PORKA  ;
DR   P51226, RBL_PORPU  ;  Q760R7, RBL_PORUM  ;  Q760T5, RBL_PORYE  ;
DR   P27568, RBL_PROHO  ;  P28444, RBL_PROLU  ;  A3PBS4, RBL_PROM0  ;
DR   A2C106, RBL_PROM1  ;  A8G3R5, RBL_PROM2  ;  A2C7U9, RBL_PROM3  ;
DR   A9BEH3, RBL_PROM4  ;  A2BVL2, RBL_PROM5  ;  Q31BY4, RBL_PROM9  ;
DR   Q7VD33, RBL_PROMA  ;  Q7V6F8, RBL_PROMM  ;  Q7V2D0, RBL_PROMP  ;
DR   A2BQ31, RBL_PROMS  ;  Q46GN1, RBL_PROMT  ;  P28445, RBL_PRUDO  ;
DR   Q3ZJ74, RBL_PSEAK  ;  Q51856, RBL_PSEHY  ;  P24681, RBL_PSEKA  ;
DR   P69571, RBL_PSEMZ  ;  P48714, RBL_PSINU  ;  Q33015, RBL_PTEVI  ;
DR   O98360, RBL_PTYGA  ;  P23651, RBL_PYLLI  ;  Q9UZD7, RBL_PYRAB  ;
DR   Q8U1P9, RBL_PYRFU  ;  O58677, RBL_PYRHO  ;  O93627, RBL_PYRKO  ;
DR   Q01874, RBL_QUERU  ;  P28446, RBL_QUIIN  ;  Q1LN92, RBL_RALME  ;
DR   P31198, RBL_RHACA  ;  A6MVT9, RBL_RHDSA  ;  P28447, RBL_RHOHI  ;
DR   Q2IT03, RBL_RHOP2  ;  Q07RX1, RBL_RHOP5  ;  Q219P7, RBL_RHOPB  ;
DR   B3Q7E1, RBL_RHOPT  ;  A3PNX7, RBL_RHOS1  ;  Q3IYC2, RBL_RHOS4  ;
DR   B9KQ06, RBL_RHOSK  ;  P31199, RBL_RIBAM  ;  P25834, RBL_RIVHU  ;
DR   P28448, RBL_RORGO  ;  P31200, RBL_ROSDA  ;  Q33050, RBL_RUBTI  ;
DR   P28449, RBL_RUTFR  ;  Q6L391, RBL_SACHY  ;  Q6ENV5, RBL_SACOF  ;
DR   P36485, RBL_SALDI  ;  P31201, RBL_SALPE  ;  P31202, RBL_SALPL  ;
DR   P28450, RBL_SANCA  ;  P28451, RBL_SARFL  ;  P36486, RBL_SAUCE  ;
DR   P28452, RBL_SAXIN  ;  Q1KVV0, RBL_SCEOB  ;  P25835, RBL_SCHTR  ;
DR   P28453, RBL_SCUBO  ;  P28454, RBL_SECDI  ;  P28455, RBL_SEDRU  ;
DR   P93880, RBL_SENDI  ;  P25836, RBL_SERRE  ;  P36487, RBL_SESIN  ;
DR   O62943, RBL_SESSE  ;  P56647, RBL_SETIT  ;  Q33062, RBL_SHEAR  ;
DR   P25837, RBL_SILGA  ;  P48715, RBL_SINAL  ;  Q2MIH9, RBL_SOLBU  ;
DR   Q33101, RBL_SOLGR  ;  P27065, RBL_SOLLC  ;  P25079, RBL_SOLTU  ;
DR   A1E9T2, RBL_SORBI  ;  Q673V5, RBL_SOVGS  ;  P27066, RBL_SOYBN  ;
DR   P36488, RBL_SPIMR  ;  P48716, RBL_SPIMX  ;  P00875, RBL_SPIOL  ;
DR   Q32RY7, RBL_STAPU  ;  P25838, RBL_STEHA  ;  P46820, RBL_STEME  ;
DR   Q06SI3, RBL_STIHE  ;  Q36800, RBL_STRLC  ;  P36489, RBL_STRNX  ;
DR   Q05993, RBL_SYMAL  ;  Q31NB3, RBL_SYNE7  ;  Q2JV67, RBL_SYNJA  ;
DR   Q2JIP3, RBL_SYNJB  ;  Q44176, RBL_SYNP2  ;  P00880, RBL_SYNP6  ;
DR   P96486, RBL_SYNPW  ;  Q7U5I8, RBL_SYNPX  ;  A5GS63, RBL_SYNR3  ;
DR   Q0I8Q2, RBL_SYNS3  ;  Q3AWU1, RBL_SYNS9  ;  Q3ALL1, RBL_SYNSC  ;
DR   Q02518, RBL_SYNSP  ;  P54205, RBL_SYNY3  ;  Q37282, RBL_TABHE  ;
DR   P93869, RBL_TAMIN  ;  P28456, RBL_TASIN  ;  Q9MVE5, RBL_TAXDI  ;
DR   O98671, RBL_TECST  ;  O98947, RBL_THANO  ;  A0T0N6, RBL_THAPS  ;
DR   Q8DIS5, RBL_THEEB  ;  B6YXA9, RBL_THEON  ;  P28457, RBL_THEPO  ;
DR   B8GQP8, RBL_THISH  ;  P00876, RBL_TOBAC  ;  Q10WH6, RBL_TRIEI  ;
DR   P25839, RBL_TRIPO  ;  P28458, RBL_TROAR  ;  P48717, RBL_TROMA  ;
DR   P26964, RBL_TSUHE  ;  Q33245, RBL_ULMAL  ;  Q33274, RBL_VALMU  ;
DR   C5CPR2, RBL_VARPS  ;  P36490, RBL_VERBO  ;  P28459, RBL_VIBAC  ;
DR   Q05803, RBL_VICCZ  ;  P05699, RBL_VICFA  ;  O62964, RBL_VIGUN  ;
DR   P27067, RBL_VIGUU  ;  Q05994, RBL_VILCA  ;  Q05995, RBL_VIOSO  ;
DR   P48718, RBL_VISAL  ;  P28460, RBL_VITAE  ;  P85085, RBL_VITSX  ;
DR   P56648, RBL_VITVI  ;  P93936, RBL_WATAN  ;  P31203, RBL_WEISI  ;
DR   P48719, RBL_WELMI  ;  P11383, RBL_WHEAT  ;  P23011, RBL_XANFL  ;
DR   A7IGM0, RBL_XANP2  ;  O98681, RBL_ZAMZA  ;  Q32RQ1, RBL_ZYGCR  ;
DR   P10647, RBS0_SOLTU ;  P10795, RBS1A_ARATH;  P10796, RBS1B_ARATH;
DR   P16134, RBS1_ACEAT ;  P16129, RBS1_ACECL ;  Q42516, RBS1_AMAHP ;
DR   P05346, RBS1_BRANA ;  P00873, RBS1_CHLRE ;  P22850, RBS1_CHRVI ;
DR   Q39743, RBS1_FLAPR ;  O24634, RBS1_FRIAG ;  Q59459, RBS1_HYDMR ;
DR   P00872, RBS1_LEMGI ;  P16032, RBS1_MESCR ;  P69250, RBS1_NICSY ;
DR   A2Y205, RBS1_ORYSI ;  Q0INY7, RBS1_ORYSJ ;  P00868, RBS1_PEA   ;
DR   P04714, RBS1_PETHY ;  P27998, RBS1_RHOSH ;  P08706, RBS1_SOLLC ;
DR   P26574, RBS1_SOLTU ;  P00865, RBS1_SOYBN ;  P00870, RBS1_SPIOL ;
DR   P28896, RBS1_THIFE ;  P00871, RBS1_WHEAT ;  P07179, RBS2A_SOLLC;
DR   P10797, RBS2B_ARATH;  P16135, RBS2_ACEAT ;  P16130, RBS2_ACECL ;
DR   P22860, RBS2_ALLVD ;  Q9XGX5, RBS2_AMAHP ;  P27985, RBS2_BRANA ;
DR   P08475, RBS2_CHLRE ;  Q39744, RBS2_FLAPR ;  O22572, RBS2_FRIAG ;
DR   Q59461, RBS2_HYDMR ;  P19308, RBS2_LEMGI ;  Q04450, RBS2_MESCR ;
DR   P22433, RBS2_NICSY ;  P18566, RBS2_ORYSJ ;  P00869, RBS2_PEA   ;
DR   P04715, RBS2_PETHY ;  Q43832, RBS2_SPIOL ;  Q07088, RBS2_THIFE ;
DR   P26667, RBS2_WHEAT ;  P07180, RBS3A_SOLLC;  P10798, RBS3B_ARATH;
DR   P05349, RBS3B_SOLLC;  P16136, RBS3_ACEAT ;  P16131, RBS3_ACECL ;
DR   Q9XGX4, RBS3_AMAHP ;  Q39745, RBS3_FLAPR ;  O22573, RBS3_FRIAG ;
DR   P19309, RBS3_LEMGI ;  Q08183, RBS3_MESCR ;  P07689, RBS3_PEA   ;
DR   P32764, RBS3_SOLTU ;  P07398, RBS3_WHEAT ;  P16137, RBS4_ACEAT ;
DR   P16132, RBS4_ACECL ;  Q39746, RBS4_FLAPR ;  P19310, RBS4_LEMGI ;
DR   Q08184, RBS4_MESCR ;  P12468, RBS4_SOYBN ;  P16138, RBS5_ACEAT ;
DR   P16133, RBS5_ACECL ;  Q39747, RBS5_FLAPR ;  O22645, RBS5_FRIAG ;
DR   P19311, RBS5_LEMGI ;  Q08185, RBS5_MESCR ;  Q38692, RBS6_ACECL ;
DR   Q39748, RBS6_FLAPR ;  P19312, RBS6_LEMGI ;  Q08186, RBS6_MESCR ;
DR   Q38693, RBS7_ACECL ;  Q39749, RBS7_FLAPR ;  P26573, RBS8_NICPL ;
DR   P26575, RBSA_SOLTU ;  P26576, RBSB_SOLTU ;  P09658, RBSC_CUPNE ;
DR   P26577, RBSC_SOLTU ;  Q59102, RBSP_CUPNH ;  Q38793, RBS_AEGTA  ;
DR   P24682, RBS_ALVHS  ;  P83160, RBS_ANASL  ;  P25458, RBS_ANTSP  ;
DR   P26985, RBS_BATOE  ;  Q96542, RBS_BETPN  ;  Q9ZI33, RBS_BRAJA  ;
DR   O65349, RBS_CAPAN  ;  P17537, RBS_CHLMO  ;  P08474, RBS_CUCSA  ;
DR   P37394, RBS_CYACA  ;  O22024, RBS_CYAME  ;  P18062, RBS_CYAPA  ;
DR   P24683, RBS_CYLSN  ;  O98946, RBS_DETCO  ;  P24395, RBS_ECTSI  ;
DR   P16881, RBS_EUGGR  ;  O22077, RBS_FAGCR  ;  P07089, RBS_FLATR  ;
DR   P23756, RBS_GALSU  ;  Q42823, RBS_GLYTA  ;  Q42822, RBS_GLYTO  ;
DR   P31333, RBS_GOSHI  ;  P14960, RBS_GUITH  ;  P45686, RBS_HALNC  ;
DR   P08705, RBS_HELAN  ;  P29684, RBS_HEVBR  ;  Q40004, RBS_HORVU  ;
DR   Q40250, RBS_LACSA  ;  P16031, RBS_LARLA  ;  P05348, RBS_MAIZE  ;
DR   Q02980, RBS_MALSP  ;  Q42915, RBS_MANES  ;  O64416, RBS_MARPA  ;
DR   O65194, RBS_MEDSA  ;  O24045, RBS_MUSAC  ;  Q59614, RBS_NITVU  ;
DR   P06514, RBS_NOSS1  ;  P49521, RBS_ODOSI  ;  P14961, RBS_OLILU  ;
DR   P80657, RBS_PHYPA  ;  P10053, RBS_PINTH  ;  Q08052, RBS_PLECA  ;
DR   Q09125, RBS_PORAE  ;  Q760S4, RBS_PORCA  ;  Q760S6, RBS_PORDE  ;
DR   Q760R4, RBS_PORHA  ;  Q760R8, RBS_PORKA  ;  P51227, RBS_PORPU  ;
DR   Q760T4, RBS_PORYE  ;  P27569, RBS_PROHO  ;  Q51857, RBS_PSEHY  ;
DR   P23652, RBS_PYLLI  ;  P24007, RBS_PYRPY  ;  P08135, RBS_RAPSA  ;
DR   P58349, RBS_RHIME  ;  O32741, RBS_RHOCA  ;  Q41373, RBS_SACHY  ;
DR   P18960, RBS_SILPR  ;  P13951, RBS_SINAL  ;  P56890, RBS_SINMW  ;
DR   Q41351, RBS_STELP  ;  Q44178, RBS_SYNP2  ;  P04716, RBS_SYNP6  ;
DR   P0A4S6, RBS_SYNPW  ;  P0A4S5, RBS_SYNPX  ;  P54206, RBS_SYNY3  ;
DR   O98948, RBS_THANO  ;  Q56260, RBS_THIDA  ;  P69249, RBS_TOBAC  ;
DR   P17673, RBS_TRIRP  ;  P23012, RBS_XANFL  ;  O48550, RBS_ZANAE  ;
//
ID   4.1.1.40
DE   Hydroxypyruvate decarboxylase.
AN   Hydroxypyruvate carboxy-lyase.
CA   Hydroxypyruvate = glycolaldehyde + CO(2).
//
ID   4.1.1.41
DE   Methylmalonyl-CoA decarboxylase.
AN   (S)-2-methyl-3-oxopropanoyl-CoA carboxy-lyase.
AN   (S)-methylmalonyl-CoA carboxy-lyase.
AN   Methylmalonyl-coenzyme A decarboxylase.
AN   Propionyl coenzyme A carboxylase.
AN   Propionyl-CoA carboxylase.
CA   (S)-methylmalonyl-CoA = propanoyl-CoA + CO(2).
CF   Biotin.
CC   -!- The enzyme from Veillonella alcalescens is a biotinyl-protein,
CC       requires sodium and acts as a sodium pump.
DR   P52045, MMCD_ECOLI ;
//
ID   4.1.1.42
DE   Carnitine decarboxylase.
AN   Carnitine carboxy-lyase.
CA   Carnitine = 2-methylcholine + CO(2).
CC   -!- Requires ATP.
//
ID   4.1.1.43
DE   Phenylpyruvate decarboxylase.
AN   Phenylpyruvate carboxy-lyase.
CA   Phenylpyruvate = phenylacetaldehyde + CO(2).
CC   -!- Also acts on (indol-3-yl)pyruvate.
//
ID   4.1.1.44
DE   4-carboxymuconolactone decarboxylase.
AN   4-carboxymuconolactone carboxy-lyase.
CA   2-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 4,5-dihydro-5-oxofuran-2-
CA   acetate + CO(2).
DR   P20370, DC4C_ACIAD ;  P00881, DC4C_PSEPU ;
//
ID   4.1.1.45
DE   Aminocarboxymuconate-semialdehyde decarboxylase.
AN   Picolinic acid decarboxylase.
CA   2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate = 2-aminomuconate
CA   semialdehyde + CO(2).
CC   -!- The product rearranges non-enzymically to picolinate.
DR   Q0II68, ACMSD_BOVIN;  Q8T8B9, ACMSD_CAEEL;  Q54LN9, ACMSD_DICDI;
DR   Q8TDX5, ACMSD_HUMAN;  Q8R519, ACMSD_MOUSE;  P83662, ACMSD_PIG  ;
DR   Q8R5M5, ACMSD_RAT  ;
//
ID   4.1.1.46
DE   o-pyrocatechuate decarboxylase.
AN   2,3-DHBA decarboxylase.
AN   2,3-dihydroxybenzoate carboxy-lyase.
AN   2,3-dihydroxybenzoic acid decarboxylase.
CA   2,3-dihydroxybenzoate = catechol + CO(2).
DR   P80346, DBD23_ASPNG;  P80402, DBD23_ASPOR;
//
ID   4.1.1.47
DE   Tartronate-semialdehyde synthase.
AN   Glyoxylate carboligase.
AN   Tartronate semialdehyde carboxylase.
CA   2 glyoxylate = tartronate semialdehyde + CO(2).
CF   Thiamine diphosphate.
DR   P0AEP8, GCL_ECO57  ;  P0AEP7, GCL_ECOLI  ;
//
ID   4.1.1.48
DE   Indole-3-glycerol-phosphate synthase.
AN   Indoleglycerol phosphate synthetase.
CA   1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-
CA   (3-indolyl)-glycerol 3-phosphate + CO(2) + H(2)O.
CC   -!- In some organisms, this enzyme is part of a multifunctional protein
CC       together with one or more components of the system for biosynthesis
CC       of tryptophan (EC 2.4.2.18, EC 4.1.3.27, EC 4.2.1.20,
CC       and EC 5.3.1.24).
PR   PROSITE; PDOC00536;
DR   Q8XVE6, TRPC1_RALSO;  O68814, TRPC1_STRCO;  Q8XS01, TRPC2_RALSO;
DR   Q9Z4X0, TRPC2_STRCO;  O28668, TRPCD_ARCFU;  B0CEU2, TRPC_ACAM1 ;
DR   A1TJQ2, TRPC_ACIAC ;  P00911, TRPC_ACIAD ;  B7I441, TRPC_ACIB5 ;
DR   B2HVE7, TRPC_ACIBC ;  Q1ISJ1, TRPC_ACIBL ;  B0VUS0, TRPC_ACIBS ;
DR   A3M785, TRPC_ACIBT ;  B0VBS1, TRPC_ACIBY ;  B9MBS5, TRPC_ACIET ;
DR   B7JBC0, TRPC_ACIF2 ;  B5ERI2, TRPC_ACIF5 ;  A1W2Z8, TRPC_ACISJ ;
DR   Q9Y8T7, TRPC_AERPE ;  B9JFD8, TRPC_AGRRK ;  Q7CYR2, TRPC_AGRT5 ;
DR   B9JX64, TRPC_AGRVS ;  A6TM74, TRPC_ALKMQ ;  O67657, TRPC_AQUAE ;
DR   P49572, TRPC_ARATH ;  A8ET36, TRPC_ARCB4 ;  Q5P2G1, TRPC_AROAE ;
DR   A1R5S7, TRPC_ARTAT ;  A0JVL1, TRPC_ARTS2 ;  P26938, TRPC_AZOBR ;
DR   A8I836, TRPC_AZOC5 ;  A1KAT2, TRPC_AZOSB ;  C1DHY7, TRPC_AZOVD ;
DR   A7Z618, TRPC_BACA2 ;  C3P3T8, TRPC_BACAA ;  C3LAW0, TRPC_BACAC ;
DR   A0RB62, TRPC_BACAH ;  Q81TM0, TRPC_BACAN ;  B7JES8, TRPC_BACC0 ;
DR   Q73BQ9, TRPC_BACC1 ;  B7IM74, TRPC_BACC2 ;  C1ELE8, TRPC_BACC3 ;
DR   B7HGZ9, TRPC_BACC4 ;  B7I0F0, TRPC_BACC7 ;  B9IU36, TRPC_BACCQ ;
DR   Q81GG7, TRPC_BACCR ;  Q63EC9, TRPC_BACCZ ;  Q9KCB2, TRPC_BACHD ;
DR   Q6HLU6, TRPC_BACHK ;  Q65I33, TRPC_BACLD ;  P70937, TRPC_BACMQ ;
DR   A8FEK0, TRPC_BACP2 ;  P18268, TRPC_BACPU ;  Q5WGS3, TRPC_BACSK ;
DR   P03964, TRPC_BACSU ;  Q8AAD6, TRPC_BACTN ;  A9VJW0, TRPC_BACWK ;
DR   B2IKL7, TRPC_BEII9 ;  C5BV85, TRPC_BEUC1 ;  Q2KU99, TRPC_BORA1 ;
DR   Q7WEK6, TRPC_BORBR ;  Q7W387, TRPC_BORPA ;  A9HY11, TRPC_BORPD ;
DR   Q7VU67, TRPC_BORPE ;  P94327, TRPC_BRAJA ;  A5EK25, TRPC_BRASB ;
DR   A4YVD6, TRPC_BRASO ;  B2S5Z1, TRPC_BRUA1 ;  Q2YRR4, TRPC_BRUA2 ;
DR   Q57CZ8, TRPC_BRUAB ;  A9M5F4, TRPC_BRUC2 ;  C0RJB1, TRPC_BRUMB ;
DR   P66988, TRPC_BRUME ;  A5VQR5, TRPC_BRUO2 ;  B0CGT9, TRPC_BRUSI ;
DR   P66989, TRPC_BRUSU ;  P57366, TRPC_BUCAI ;  P42393, TRPC_BUCAP ;
DR   P59459, TRPC_BUCBP ;  O68427, TRPC_BUCDN ;  Q44603, TRPC_BUCSC ;
DR   B1YSF5, TRPC_BURA4 ;  Q1BSD2, TRPC_BURCA ;  B1JUU5, TRPC_BURCC ;
DR   A0K458, TRPC_BURCH ;  Q0BIM8, TRPC_BURCM ;  A9AJ43, TRPC_BURM1 ;
DR   A3MFQ4, TRPC_BURM7 ;  A2RYI3, TRPC_BURM9 ;  Q62DD0, TRPC_BURMA ;
DR   A1UWA0, TRPC_BURMS ;  A3NZP6, TRPC_BURP0 ;  Q3JNB0, TRPC_BURP1 ;
DR   A3NDZ3, TRPC_BURP6 ;  B2JHI8, TRPC_BURP8 ;  B2SZ04, TRPC_BURPP ;
DR   Q63QH0, TRPC_BURPS ;  Q39JZ7, TRPC_BURS3 ;  Q2SUI0, TRPC_BURTA ;
DR   A4JB67, TRPC_BURVG ;  Q13TW4, TRPC_BURXL ;  A8Z6K1, TRPC_CAMC1 ;
DR   A7GYQ7, TRPC_CAMC5 ;  A0RNN3, TRPC_CAMFF ;  A7I2Y2, TRPC_CAMHC ;
DR   A8FKS2, TRPC_CAMJ8 ;  A7H4P0, TRPC_CAMJD ;  Q9PI11, TRPC_CAMJE ;
DR   A1VYK3, TRPC_CAMJJ ;  Q5HVR3, TRPC_CAMJR ;  Q3ABS1, TRPC_CARHZ ;
DR   B8GWP9, TRPC_CAUCN ;  Q9A727, TRPC_CAUCR ;  B0SYZ4, TRPC_CAUSK ;
DR   Q3AU73, TRPC_CHLCH ;  B3EG28, TRPC_CHLL2 ;  B3QLY7, TRPC_CHLP8 ;
DR   A1BDW1, TRPC_CHLPD ;  B3QZD6, TRPC_CHLT3 ;  Q8KBW1, TRPC_CHLTE ;
DR   Q7NUI6, TRPC_CHRVO ;  Q97EF3, TRPC_CLOAB ;  B8I0V0, TRPC_CLOCE ;
DR   B9E149, TRPC_CLOK1 ;  A5N7N8, TRPC_CLOK5 ;  A9KL43, TRPC_CLOPH ;
DR   A3DDS7, TRPC_CLOTH ;  P06560, TRPC_CORGL ;  Q0K6I0, TRPC_CUPNH ;
DR   Q46WU7, TRPC_CUPPJ ;  B3R703, TRPC_CUPTR ;  B1WQE4, TRPC_CYAA5 ;
DR   B8HP79, TRPC_CYAP4 ;  B7K0H0, TRPC_CYAP8 ;  Q47AC7, TRPC_DECAR ;
DR   Q3Z6G5, TRPC_DEHE1 ;  A5FPM3, TRPC_DEHSB ;  Q3ZZ14, TRPC_DEHSC ;
DR   Q9RUG0, TRPC_DEIRA ;  A9BS06, TRPC_DELAS ;  A8ZZX0, TRPC_DESOH ;
DR   Q6AMS4, TRPC_DESPS ;  A4J147, TRPC_DESRM ;  A5EVG3, TRPC_DICNV ;
DR   Q8X7B7, TRPC_ECO57 ;  P00909, TRPC_ECOLI ;  C4Z138, TRPC_EUBE2 ;
DR   B1YLS2, TRPC_EXIS2 ;  C4KZ66, TRPC_EXISA ;  Q0RFX9, TRPC_FRAAA ;
DR   A8LGR8, TRPC_FRASN ;  Q5KXU9, TRPC_GEOKA ;  C5D3D6, TRPC_GEOSW ;
DR   A4IQ84, TRPC_GEOTN ;  Q7NHI0, TRPC_GLOVI ;  P46451, TRPC_HAEIN ;
DR   Q5V138, TRPC_HALMA ;  Q9HSC1, TRPC_HALSA ;  P18304, TRPC_HALVD ;
DR   Q9ZJU8, TRPC_HELPJ ;  O25867, TRPC_HELPY ;  A4G1P4, TRPC_HERAR ;
DR   Q0C1A2, TRPC_HYPNA ;  A6SUH5, TRPC_JANMA ;  A6WC91, TRPC_KINRD ;
DR   Q03CY1, TRPC_LACC3 ;  P17217, TRPC_LACCA ;  B3W6W8, TRPC_LACCB ;
DR   Q01999, TRPC_LACLA ;  A2RK21, TRPC_LACLM ;  Q02YB4, TRPC_LACLS ;
DR   Q88WI2, TRPC_LACPL ;  C1D7J7, TRPC_LARHH ;  Q5X6S0, TRPC_LEGPA ;
DR   A5IG82, TRPC_LEGPC ;  Q5ZX99, TRPC_LEGPH ;  Q5WY75, TRPC_LEGPL ;
DR   Q6AF68, TRPC_LEIXX ;  B1Y7I2, TRPC_LEPCP ;  Q72NP6, TRPC_LEPIC ;
DR   Q8F7V2, TRPC_LEPIN ;  Q03X00, TRPC_LEUMM ;  Q92B79, TRPC_LISIN ;
DR   C1KVS7, TRPC_LISMC ;  Q71Z38, TRPC_LISMF ;  B8DHB2, TRPC_LISMH ;
DR   Q8Y6Q4, TRPC_LISMO ;  A0AJ82, TRPC_LISW6 ;  A0LA39, TRPC_MAGSM ;
DR   Q11HU1, TRPC_MESSB ;  Q58328, TRPC_METJA ;  Q8TVJ8, TRPC_METKA ;
DR   A4YHD8, TRPC_METS5 ;  B8EJS1, TRPC_METSB ;  O27694, TRPC_METTH ;
DR   P26939, TRPC_METTM ;  B0JTM2, TRPC_MICAN ;  C5CBK6, TRPC_MICLC ;
DR   A0QHH0, TRPC_MYCA1 ;  B1MBV4, TRPC_MYCA9 ;  P0A633, TRPC_MYCBO ;
DR   A1KJ27, TRPC_MYCBP ;  C1ANN3, TRPC_MYCBT ;  A4T9N5, TRPC_MYCGI ;
DR   B8ZRB9, TRPC_MYCLB ;  Q9X7C7, TRPC_MYCLE ;  B2HQX7, TRPC_MYCMM ;
DR   Q740P4, TRPC_MYCPA ;  A0QX95, TRPC_MYCS2 ;  A3Q119, TRPC_MYCSJ ;
DR   A1UHJ6, TRPC_MYCSK ;  Q1B7H6, TRPC_MYCSS ;  A5U2W7, TRPC_MYCTA ;
DR   P0A632, TRPC_MYCTU ;  A0PP28, TRPC_MYCUA ;  A1T8X3, TRPC_MYCVP ;
DR   B9LAF4, TRPC_NAUPA ;  Q5F645, TRPC_NEIG1 ;  B4RPF1, TRPC_NEIG2 ;
DR   Q9JSN4, TRPC_NEIMA ;  Q9K192, TRPC_NEIMB ;  A1KRV4, TRPC_NEIMF ;
DR   Q1QMJ9, TRPC_NITHX ;  A6Q3P0, TRPC_NITSB ;  Q3SRJ3, TRPC_NITWN ;
DR   A1SL44, TRPC_NOCSJ ;  Q2G6R0, TRPC_NOVAD ;  Q8ESU2, TRPC_OCEIH ;
DR   A6X0L0, TRPC_OCHA4 ;  B6JG29, TRPC_OLICO ;  B1ZW79, TRPC_OPITP ;
DR   A7HXZ6, TRPC_PARL1 ;  P57855, TRPC_PASMU ;  Q3B2C7, TRPC_PELLD ;
DR   B4SDV8, TRPC_PELPB ;  A9BHQ5, TRPC_PETMO ;  B4RBX5, TRPC_PHEZH ;
DR   P24920, TRPC_PHYPR ;  Q6L277, TRPC_PICTO ;  A1VTG7, TRPC_POLNA ;
DR   B1XSZ1, TRPC_POLNS ;  Q123F4, TRPC_POLSJ ;  A4SV52, TRPC_POLSQ ;
DR   A3PED0, TRPC_PROM0 ;  A2C462, TRPC_PROM1 ;  A8G6A7, TRPC_PROM2 ;
DR   A2CB59, TRPC_PROM3 ;  A9BBR3, TRPC_PROM4 ;  A2BY04, TRPC_PROM5 ;
DR   Q319J2, TRPC_PROM9 ;  Q7VAT3, TRPC_PROMA ;  Q7TV44, TRPC_PROMM ;
DR   Q7TU64, TRPC_PROMP ;  A2BSL8, TRPC_PROMS ;  Q46JH4, TRPC_PROMT ;
DR   A4SG41, TRPC_PROVI ;  Q48NP7, TRPC_PSE14 ;  A6UZF2, TRPC_PSEA7 ;
DR   B7V609, TRPC_PSEA8 ;  Q02TB5, TRPC_PSEAB ;  P20577, TRPC_PSEAE ;
DR   Q1IFZ9, TRPC_PSEE4 ;  Q4K503, TRPC_PSEF5 ;  C3K307, TRPC_PSEFS ;
DR   A4XZC5, TRPC_PSEMY ;  A5VXL5, TRPC_PSEP1 ;  Q3K5V4, TRPC_PSEPF ;
DR   B0KK35, TRPC_PSEPG ;  Q88QR6, TRPC_PSEPK ;  P20578, TRPC_PSEPU ;
DR   B1JE34, TRPC_PSEPW ;  Q88A03, TRPC_PSESM ;  A4VHK1, TRPC_PSEU5 ;
DR   Q9V1G3, TRPC_PYRAB ;  Q8ZYX2, TRPC_PYRAE ;  A4WN19, TRPC_PYRAR ;
DR   Q8U088, TRPC_PYRFU ;  Q9YGB5, TRPC_PYRKO ;  B2UDK9, TRPC_RALPJ ;
DR   B3Q0L3, TRPC_RHIE6 ;  Q2K879, TRPC_RHIEC ;  Q1MGE1, TRPC_RHIL3 ;
DR   Q98ME3, TRPC_RHILO ;  B5ZPY7, TRPC_RHILW ;  Q92PR9, TRPC_RHIME ;
DR   C3MCF2, TRPC_RHISN ;  Q7UKJ7, TRPC_RHOBA ;  Q02584, TRPC_RHOCB ;
DR   Q21SE8, TRPC_RHOFD ;  C1AT55, TRPC_RHOOB ;  Q2IWB0, TRPC_RHOP2 ;
DR   Q07NF6, TRPC_RHOP5 ;  Q215B9, TRPC_RHOPB ;  Q136D2, TRPC_RHOPS ;
DR   B3Q6M9, TRPC_RHOPT ;  Q2RT48, TRPC_RHORT ;  A3PHK7, TRPC_RHOS1 ;
DR   Q9ZFA7, TRPC_RHOS4 ;  A4WX67, TRPC_RHOS5 ;  B9KMV0, TRPC_RHOSK ;
DR   Q0SHZ5, TRPC_RHOSR ;  A7NMZ8, TRPC_ROSCS ;  A5USQ4, TRPC_ROSS1 ;
DR   A4FLL0, TRPC_SACEN ;  Q2S1Z5, TRPC_SALRD ;  Q8Z7D9, TRPC_SALTI ;
DR   P00910, TRPC_SALTY ;  A6U9C5, TRPC_SINMW ;  A5VBA0, TRPC_SPHWW ;
DR   A7X234, TRPC_STAA1 ;  A6U1J2, TRPC_STAA2 ;  Q2FH66, TRPC_STAA3 ;
DR   Q2FYR6, TRPC_STAA8 ;  A5ISQ2, TRPC_STAA9 ;  Q2YXU9, TRPC_STAAB ;
DR   Q9RL78, TRPC_STAAC ;  A6QGS2, TRPC_STAAE ;  P66990, TRPC_STAAM ;
DR   P66991, TRPC_STAAN ;  Q6GH35, TRPC_STAAR ;  Q6G9I9, TRPC_STAAS ;
DR   A8Z242, TRPC_STAAT ;  Q8NWU3, TRPC_STAAW ;  Q5HPH2, TRPC_STAEQ ;
DR   Q8CPB2, TRPC_STAES ;  Q4L677, TRPC_STAHJ ;  Q49XH6, TRPC_STAS1 ;
DR   Q82A84, TRPC_STRAW ;  A8AW03, TRPC_STRGC ;  B1W0N8, TRPC_STRGG ;
DR   B4SLE8, TRPC_STRM5 ;  B2FKL1, TRPC_STRMK ;  Q8DVF5, TRPC_STRMU ;
DR   Q04IY7, TRPC_STRP2 ;  B5E7M5, TRPC_STRP4 ;  C1C968, TRPC_STRP7 ;
DR   B1I7S9, TRPC_STRPI ;  B8ZN61, TRPC_STRPJ ;  Q97P30, TRPC_STRPN ;
DR   B2ISS3, TRPC_STRPS ;  Q8DNM6, TRPC_STRR6 ;  A3CLL9, TRPC_STRSV ;
DR   Q5LYI5, TRPC_STRT1 ;  Q5M348, TRPC_STRT2 ;  Q03JB9, TRPC_STRTD ;
DR   C1CG44, TRPC_STRZJ ;  C1CMD5, TRPC_STRZP ;  C1CT53, TRPC_STRZT ;
DR   Q4J8X3, TRPC_SULAC ;  Q30SM1, TRPC_SULDN ;  Q06121, TRPC_SULSO ;
DR   Q972A1, TRPC_SULTO ;  Q8KPR4, TRPC_SYNE7 ;  A0LJ58, TRPC_SYNFM ;
DR   Q5N575, TRPC_SYNP6 ;  A5GMK4, TRPC_SYNPW ;  Q7TTU3, TRPC_SYNPX ;
DR   A5GRL0, TRPC_SYNR3 ;  Q0IC57, TRPC_SYNS3 ;  Q3AV87, TRPC_SYNS9 ;
DR   Q3AL94, TRPC_SYNSC ;  Q55508, TRPC_SYNY3 ;  Q9HK02, TRPC_THEAC ;
DR   Q47QR5, TRPC_THEFY ;  Q56319, TRPC_THEMA ;  B1YBK5, TRPC_THENV ;
DR   B0K8T4, TRPC_THEP3 ;  B0K2U1, TRPC_THEPX ;  Q8R9M7, TRPC_THETN ;
DR   Q979V9, TRPC_THEVO ;  Q3SGS2, TRPC_THIDA ;  Q10ZM7, TRPC_TRIEI ;
DR   B1GZC0, TRPC_UNCTG ;  C5CKE4, TRPC_VARPS ;  A1WH73, TRPC_VEREI ;
DR   Q9KST5, TRPC_VIBCH ;  P22098, TRPC_VIBPA ;  Q7M831, TRPC_WOLSU ;
DR   Q8PQ47, TRPC_XANAC ;  Q3BYB5, TRPC_XANC5 ;  Q4UZF8, TRPC_XANC8 ;
DR   Q8PD70, TRPC_XANCP ;  Q2NYD7, TRPC_XANOM ;  B2SL03, TRPC_XANOP ;
DR   A7INK2, TRPC_XANP2 ;  B2I6S5, TRPC_XYLF2 ;  Q9PGT5, TRPC_XYLFA ;
DR   B0U1P0, TRPC_XYLFM ;  Q87EX2, TRPC_XYLFT ;  Q8ZEG8, TRPC_YERPE ;
DR   Q5NQ36, TRPC_ZYMMO ;  Q9XBM3, TRPC_ZYMMP ;  P18483, TRPG_ASPAW ;
DR   P05328, TRPG_ASPNG ;  Q92411, TRPG_COCHE ;  P0CN87, TRPG_CRYNB ;
DR   P0CN86, TRPG_CRYNJ ;  P27710, TRPG_CRYNV ;  P06531, TRPG_EMENI ;
DR   P00908, TRPG_NEUCR ;  P24773, TRPG_PENCH ;  P25170, TRPG_PHACH ;
DR   P20409, TRPG_PHYBL ;  P09575, TRPG_PICAN ;  Q92370, TRPG_SCHPO ;
DR   P00937, TRPG_YEAST ;
//
ID   4.1.1.49
DE   Phosphoenolpyruvate carboxykinase (ATP).
AN   PEP carboxykinase.
AN   PEPCK.
AN   Phosphoenolpyruvate carboxykinase.
AN   Phosphoenolpyruvate carboxylase.
AN   Phosphopyruvate carboxylase.
CA   ATP + oxaloacetate = ADP + phosphoenolpyruvate + CO(2).
PR   PROSITE; PDOC00460;
DR   Q2RKS7, PCKA1_MOOTA;  Q2S1I3, PCKA1_SALRD;  P49292, PCKA1_UROPA;
DR   Q2RH96, PCKA2_MOOTA;  Q2S008, PCKA2_SALRD;  Q9XFA2, PCKA2_UROPA;
DR   A3N0G0, PCKA_ACTP2 ;  B3H1D9, PCKA_ACTP7 ;  B0BP80, PCKA_ACTPJ ;
DR   A6VKV4, PCKA_ACTSZ ;  Q9YG68, PCKA_AERPE ;  B9JG59, PCKA_AGRRK ;
DR   Q8UJ94, PCKA_AGRT5 ;  B9JXX4, PCKA_AGRVS ;  B6EGP7, PCKA_ALISL ;
DR   A8MEV2, PCKA_ALKOO ;  B3ET45, PCKA_AMOA5 ;  O09460, PCKA_ANASU ;
DR   Q9T074, PCKA_ARATH ;  Q753M0, PCKA_ASHGO ;  A8ILP8, PCKA_AZOC5 ;
DR   B6YRN4, PCKA_AZOPC ;  A7Z7Z0, PCKA_BACA2 ;  C3PCC6, PCKA_BACAA ;
DR   A0RJZ8, PCKA_BACAH ;  Q81KH8, PCKA_BACAN ;  B7JT33, PCKA_BACC0 ;
DR   Q72YV4, PCKA_BACC1 ;  B7IL29, PCKA_BACC2 ;  C1EW38, PCKA_BACC3 ;
DR   B7H9C8, PCKA_BACC4 ;  B7HSV7, PCKA_BACC7 ;  A7GU41, PCKA_BACCN ;
DR   B9J266, PCKA_BACCQ ;  Q816Q7, PCKA_BACCR ;  Q632S4, PCKA_BACCZ ;
DR   Q5L7N5, PCKA_BACFN ;  Q64MV4, PCKA_BACFR ;  Q9K7Q7, PCKA_BACHD ;
DR   Q6HCB3, PCKA_BACHK ;  Q65FV7, PCKA_BACLD ;  A8FGH8, PCKA_BACP2 ;
DR   Q5WDZ7, PCKA_BACSK ;  P54418, PCKA_BACSU ;  Q8A414, PCKA_BACTN ;
DR   A9VLC7, PCKA_BACWK ;  Q1LU72, PCKA_BAUCH ;  Q89BK7, PCKA_BRAJA ;
DR   A5EST5, PCKA_BRASB ;  A4YL90, PCKA_BRASO ;  C0ZL09, PCKA_BREBN ;
DR   A9M9S3, PCKA_BRUC2 ;  Q8YE41, PCKA_BRUME ;  Q8FY05, PCKA_BRUSU ;
DR   A8FLY1, PCKA_CAMJ8 ;  A7H3B9, PCKA_CAMJD ;  Q9PP01, PCKA_CAMJE ;
DR   A1VZR5, PCKA_CAMJJ ;  Q5HUM7, PCKA_CAMJR ;  B9KD79, PCKA_CAMLR ;
DR   O13434, PCKA_CANAL ;  Q6FRR0, PCKA_CANGA ;  A8AQV7, PCKA_CITK8 ;
DR   Q47VD0, PCKA_COLP3 ;  B6J6M2, PCKA_COXB1 ;  B6J3V5, PCKA_COXB2 ;
DR   A9KDE5, PCKA_COXBN ;  A9NBT9, PCKA_COXBR ;  Q83A19, PCKA_COXBU ;
DR   P42066, PCKA_CUCSA ;  Q1IZ41, PCKA_DEIGD ;  Q9RVP6, PCKA_DEIRA ;
DR   Q75JD5, PCKA_DICDI ;  A8LLF2, PCKA_DINSH ;  A7ZST1, PCKA_ECO24 ;
DR   B7UKA7, PCKA_ECO27 ;  B7MDM9, PCKA_ECO45 ;  B7L4T1, PCKA_ECO55 ;
DR   Q8X733, PCKA_ECO57 ;  B5YTV3, PCKA_ECO5E ;  B7NMG6, PCKA_ECO7I ;
DR   B7N136, PCKA_ECO81 ;  B7M1V7, PCKA_ECO8A ;  C4ZUQ8, PCKA_ECOBW ;
DR   B1X750, PCKA_ECODH ;  A8A5L1, PCKA_ECOHS ;  A1AGS9, PCKA_ECOK1 ;
DR   Q0TC64, PCKA_ECOL5 ;  Q8FCU4, PCKA_ECOL6 ;  B1IP62, PCKA_ECOLC ;
DR   P22259, PCKA_ECOLI ;  B7NE08, PCKA_ECOLU ;  B6I2W3, PCKA_ECOSE ;
DR   B1LHK1, PCKA_ECOSM ;  C5BGS4, PCKA_EDWI9 ;  Q96UL8, PCKA_EMENI ;
DR   A4WFJ1, PCKA_ENT38 ;  A7MGC5, PCKA_ENTS8 ;  Q6CZP5, PCKA_ERWCT ;
DR   B2VJU9, PCKA_ERWT9 ;  B7LSA4, PCKA_ESCF3 ;  C4Z0Q6, PCKA_EUBE2 ;
DR   C4ZBL1, PCKA_EUBR3 ;  A5FK68, PCKA_FLAJ1 ;  Q8REI2, PCKA_FUSNN ;
DR   Q5KW01, PCKA_GEOKA ;  Q39QU2, PCKA_GEOMG ;  C6E0Y2, PCKA_GEOSM ;
DR   A4IRZ2, PCKA_GEOTN ;  A5GBF9, PCKA_GEOUR ;  A0LXJ9, PCKA_GRAFK ;
DR   Q7VLT3, PCKA_HAEDU ;  Q4QM91, PCKA_HAEI8 ;  A5UDR5, PCKA_HAEIE ;
DR   A5UHW1, PCKA_HAEIG ;  P43923, PCKA_HAEIN ;  B8F4W1, PCKA_HAEPS ;
DR   Q0I554, PCKA_HAES1 ;  B0UWS7, PCKA_HAES2 ;  Q2SPF9, PCKA_HAHCH ;
DR   C4K3J5, PCKA_HAMD5 ;  Q5QUN4, PCKA_IDILO ;  O43112, PCKA_KLULA ;
DR   B0SFJ3, PCKA_LEPBA ;  B0SPF0, PCKA_LEPBP ;  Q72VT0, PCKA_LEPIC ;
DR   Q8F9E4, PCKA_LEPIN ;  B1HXZ6, PCKA_LYSSC ;  Q9SLZ0, PCKA_MAIZE ;
DR   Q65Q60, PCKA_MANSM ;  A1U754, PCKA_MARAV ;  Q0AQP4, PCKA_MARMM ;
DR   Q11CK2, PCKA_MESSB ;  B7KVW8, PCKA_METC4 ;  A9W382, PCKA_METEP ;
DR   B8IMT2, PCKA_METNO ;  B1ZG99, PCKA_METPB ;  B1M6N5, PCKA_METRJ ;
DR   B0UFE2, PCKA_METS4 ;  Q7RVS9, PCKA_NEUCR ;  Q1QR12, PCKA_NITHX ;
DR   A6Q102, PCKA_NITSB ;  Q3SVS4, PCKA_NITWN ;  Q2G480, PCKA_NOVAD ;
DR   Q8EP04, PCKA_OCEIH ;  A6WX47, PCKA_OCHA4 ;  B6JJT0, PCKA_OLICO ;
DR   A6LFQ4, PCKA_PARD8 ;  A1B5Z2, PCKA_PARDP ;  A7HP99, PCKA_PARL1 ;
DR   Q9CKR4, PCKA_PASMU ;  C6DGE8, PCKA_PECCP ;  A1AV24, PCKA_PELPD ;
DR   Q7NA45, PCKA_PHOLL ;  Q6LLS2, PCKA_PHOPR ;  B2RHV8, PCKA_PORG3 ;
DR   Q7MU78, PCKA_PORGI ;  B4F025, PCKA_PROMH ;  Q48BY7, PCKA_PSE14 ;
DR   A6VDW7, PCKA_PSEA7 ;  B7V3T9, PCKA_PSEA8 ;  Q02EH2, PCKA_PSEAB ;
DR   Q9HTZ7, PCKA_PSEAE ;  Q1IGK1, PCKA_PSEE4 ;  Q4KK03, PCKA_PSEF5 ;
DR   C3K4J5, PCKA_PSEFS ;  Q3ILP3, PCKA_PSEHT ;  A4XP75, PCKA_PSEMY ;
DR   A5VX32, PCKA_PSEP1 ;  Q3KJP4, PCKA_PSEPF ;  B0KI05, PCKA_PSEPG ;
DR   B1JET1, PCKA_PSEPW ;  Q88AZ4, PCKA_PSESM ;  Q500D1, PCKA_PSEU2 ;
DR   B3PWH4, PCKA_RHIE6 ;  Q2KE66, PCKA_RHIEC ;  Q1MNG2, PCKA_RHIL3 ;
DR   Q98CL7, PCKA_RHILO ;  B5ZV86, PCKA_RHILW ;  P43085, PCKA_RHIME ;
DR   P43086, PCKA_RHISN ;  Q2J2Y8, PCKA_RHOP2 ;  Q07TF9, PCKA_RHOP5 ;
DR   Q9ZNH4, PCKA_RHOPA ;  Q21BR2, PCKA_RHOPB ;  Q13E86, PCKA_RHOPS ;
DR   B3Q999, PCKA_RHOPT ;  A3PGG3, PCKA_RHOS1 ;  Q3J5V6, PCKA_RHOS4 ;
DR   A4WVP0, PCKA_RHOS5 ;  Q16AH6, PCKA_ROSDO ;  Q1AY78, PCKA_RUBXD ;
DR   B5F8L6, PCKA_SALA4 ;  A9MMC5, PCKA_SALAR ;  Q57IX4, PCKA_SALCH ;
DR   B5FJS1, PCKA_SALDC ;  B5R360, PCKA_SALEP ;  B5R7L4, PCKA_SALG2 ;
DR   B4TKS6, PCKA_SALHS ;  B4SVK3, PCKA_SALNS ;  Q5PLX8, PCKA_SALPA ;
DR   A9MT72, PCKA_SALPB ;  C0Q0H5, PCKA_SALPC ;  B5BHF8, PCKA_SALPK ;
DR   B4TY59, PCKA_SALSV ;  Q8Z216, PCKA_SALTI ;  P41033, PCKA_SALTY ;
DR   O83023, PCKA_SELRU ;  A1S1X0, PCKA_SHEAM ;  B8E3X7, PCKA_SHEB2 ;
DR   A3DAB2, PCKA_SHEB5 ;  A6WHM7, PCKA_SHEB8 ;  A9KVC7, PCKA_SHEB9 ;
DR   Q12T12, PCKA_SHEDO ;  Q089V1, PCKA_SHEFN ;  B0TMY0, PCKA_SHEHH ;
DR   A3QJ41, PCKA_SHELP ;  Q8EKD3, PCKA_SHEON ;  A8GYT2, PCKA_SHEPA ;
DR   A4YBE7, PCKA_SHEPC ;  B8CH32, PCKA_SHEPW ;  A0KRH2, PCKA_SHESA ;
DR   A8G1J1, PCKA_SHESH ;  Q0HNY4, PCKA_SHESM ;  Q0I0F2, PCKA_SHESR ;
DR   A1RPC2, PCKA_SHESW ;  B1KN33, PCKA_SHEWM ;  B2U3L1, PCKA_SHIB3 ;
DR   Q31VN1, PCKA_SHIBS ;  Q32AL7, PCKA_SHIDS ;  Q0SZR5, PCKA_SHIF8 ;
DR   Q83J96, PCKA_SHIFL ;  Q3YWM2, PCKA_SHISS ;  Q5LVJ2, PCKA_SILPO ;
DR   Q1GDU2, PCKA_SILST ;  A6UEJ7, PCKA_SINMW ;  Q2NQI3, PCKA_SODGM ;
DR   A7X3N3, PCKA_STAA1 ;  A6U2Q2, PCKA_STAA2 ;  Q2FFV5, PCKA_STAA3 ;
DR   Q2G1W2, PCKA_STAA8 ;  A5ITV7, PCKA_STAA9 ;  Q2YTK0, PCKA_STAAB ;
DR   Q5HEY8, PCKA_STAAC ;  A6QHX1, PCKA_STAAE ;  P0A0B3, PCKA_STAAM ;
DR   P99128, PCKA_STAAN ;  Q6GFR5, PCKA_STAAR ;  Q6G8E2, PCKA_STAAS ;
DR   A8Z4L3, PCKA_STAAT ;  P0C1S4, PCKA_STAAU ;  Q8NVZ8, PCKA_STAAW ;
DR   B9DN20, PCKA_STACT ;  Q5HNB7, PCKA_STAEQ ;  Q8CS25, PCKA_STAES ;
DR   Q4L7C9, PCKA_STAHJ ;  Q49YL7, PCKA_STAS1 ;  Q30PV8, PCKA_SULDN ;
DR   Q72GY7, PCKA_THET2 ;  Q5SLL5, PCKA_THET8 ;  Q8R943, PCKA_THETN ;
DR   P13735, PCKA_TRYBB ;  P51058, PCKA_TRYCR ;  A5F4Q4, PCKA_VIBC3 ;
DR   Q9KNK0, PCKA_VIBCH ;  C3LSG5, PCKA_VIBCM ;  Q5E1X3, PCKA_VIBF1 ;
DR   B5FCE7, PCKA_VIBFM ;  A7MZB2, PCKA_VIBHB ;  Q87TE1, PCKA_VIBPA ;
DR   B7VHF2, PCKA_VIBSL ;  Q8DDS6, PCKA_VIBVU ;  Q7MQ03, PCKA_VIBVY ;
DR   Q8D1X9, PCKA_WIGBR ;  P10963, PCKA_YEAST ;  A1JSE7, PCKA_YERE8 ;
DR   A7FNU8, PCKA_YERP3 ;  Q1C2M9, PCKA_YERPA ;  B2K5U8, PCKA_YERPB ;
DR   Q8ZJG9, PCKA_YERPE ;  A9R4C2, PCKA_YERPG ;  Q1CCM6, PCKA_YERPN ;
DR   A4TGS8, PCKA_YERPP ;  Q664K7, PCKA_YERPS ;  B1JI04, PCKA_YERPY ;
//
ID   4.1.1.50
DE   Adenosylmethionine decarboxylase.
AN   S-adenosyl-L-methionine carboxy-lyase.
AN   S-adenosyl-L-methionine decarboxylase.
CA   S-adenosyl-L-methionine = (5-deoxy-5-adenosyl)(3-aminopropyl)-
CA   methylsulfonium salt + CO(2).
CF   Pyruvate.
PR   PROSITE; PDOC01038;
DR   Q96286, DCAM1_ARATH;  Q42613, DCAM1_BRAJU;  Q39676, DCAM1_DIACA;
DR   P31154, DCAM1_MOUSE;  Q9S7T9, DCAM2_ARATH;  O49972, DCAM2_BRAJU;
DR   Q39677, DCAM2_DIACA;  P82184, DCAM2_MOUSE;  P82185, DCAM2_MUSSP;
DR   Q9SDM8, DCAM3_BRAJU;  P34039, DCAM_ACACA ;  P50243, DCAM_BOVIN ;
DR   O02655, DCAM_CAEEL ;  Q42679, DCAM_CATRO ;  Q96555, DCAM_DATST ;
DR   Q9AXE3, DCAM_DAUCA ;  Q8T1E3, DCAM_DICDI ;  P91931, DCAM_DROME ;
DR   O65354, DCAM_HELAN ;  Q42829, DCAM_HORCH ;  P17707, DCAM_HUMAN ;
DR   Q9M6K1, DCAM_IPOBA ;  Q96471, DCAM_IPONI ;  Q25264, DCAM_LEIDO ;
DR   Q9NGA0, DCAM_LEIIN ;  O24575, DCAM_MAIZE ;  P28918, DCAM_MESAU ;
DR   O80402, DCAM_NICSY ;  Q27883, DCAM_ONCVO ;  A2XV58, DCAM_ORYSI ;
DR   Q0JC10, DCAM_ORYSJ ;  Q43820, DCAM_PEA   ;  P17708, DCAM_RAT   ;
DR   Q9P7E3, DCAM_SCHPO ;  Q38IY3, DCAM_SOLCI ;  Q04694, DCAM_SOLTU ;
DR   P46255, DCAM_SPIOL ;  O04009, DCAM_TOBAC ;  P50244, DCAM_TRYBB ;
DR   O76240, DCAM_TRYCR ;  Q9M4D8, DCAM_VICFA ;  P79888, DCAM_XENLA ;
DR   P21182, DCAM_YEAST ;  Q0VMX9, SPED_ALCBS ;  Q0A6F1, SPED_ALHEH ;
DR   A6TS03, SPED_ALKMQ ;  A8MLM7, SPED_ALKOO ;  C1DHY4, SPED_AZOVD ;
DR   C0Z4Q5, SPED_BREBN ;  B8D907, SPED_BUCA5 ;  P57304, SPED_BUCAI ;
DR   Q8K9T6, SPED_BUCAP ;  B8D7B2, SPED_BUCAT ;  Q1QZ38, SPED_CHRSD ;
DR   A8ALG9, SPED_CITK8 ;  Q97FX4, SPED_CLOAB ;  A6M1P1, SPED_CLOB8 ;
DR   B2V2S2, SPED_CLOBA ;  B2TML8, SPED_CLOBB ;  Q0TTQ9, SPED_CLOP1 ;
DR   Q8XMZ0, SPED_CLOPE ;  Q0SVK9, SPED_CLOPS ;  B8G177, SPED_DESHD ;
DR   Q24PX9, SPED_DESHY ;  A7ZHK9, SPED_ECO24 ;  B7UIG8, SPED_ECO27 ;
DR   B7MBA3, SPED_ECO45 ;  B7LFY7, SPED_ECO55 ;  P0A7F7, SPED_ECO57 ;
DR   B5YZF5, SPED_ECO5E ;  B7NI80, SPED_ECO7I ;  B7MNY2, SPED_ECO81 ;
DR   B7M161, SPED_ECO8A ;  C4ZRL3, SPED_ECOBW ;  B1XC95, SPED_ECODH ;
DR   A7ZW69, SPED_ECOHS ;  Q0TLL4, SPED_ECOL5 ;  Q8FL39, SPED_ECOL6 ;
DR   B1IQM0, SPED_ECOLC ;  P0A7F6, SPED_ECOLI ;  B7N7Z0, SPED_ECOLU ;
DR   B1LGS1, SPED_ECOSM ;  Q1RG71, SPED_ECOUT ;  A4W6M5, SPED_ENT38 ;
DR   A7MGP2, SPED_ENTS8 ;  Q6D1W3, SPED_ERWCT ;  B2VD29, SPED_ERWT9 ;
DR   B7LVY2, SPED_ESCF3 ;  Q5L051, SPED_GEOKA ;  A4IMR9, SPED_GEOTN ;
DR   Q2S990, SPED_HAHCH ;  A1WYT0, SPED_HALHL ;  C4K3X2, SPED_HAMD5 ;
DR   B0TI92, SPED_HELMI ;  B5Y1R2, SPED_KLEP3 ;  A6T4R5, SPED_KLEP7 ;
DR   A1U6K2, SPED_MARAV ;  Q607L0, SPED_METCA ;  Q3JCI4, SPED_NITOC ;
DR   C6DC59, SPED_PECCP ;  Q7N893, SPED_PHOLL ;  Q48NP3, SPED_PSE14 ;
DR   A6UZF5, SPED_PSEA7 ;  B7V612, SPED_PSEA8 ;  Q02TB2, SPED_PSEAB ;
DR   Q9I5R7, SPED_PSEAE ;  Q3IFT4, SPED_PSEHT ;  Q3K5V8, SPED_PSEPF ;
DR   Q889Z9, SPED_PSESM ;  Q4ZML7, SPED_PSEU2 ;  B5F814, SPED_SALA4 ;
DR   A9MPN4, SPED_SALAR ;  Q57T90, SPED_SALCH ;  B5FIB3, SPED_SALDC ;
DR   B5R2R4, SPED_SALEP ;  B5RHA4, SPED_SALG2 ;  B4TJD1, SPED_SALHS ;
DR   B4SU90, SPED_SALNS ;  Q5PDA1, SPED_SALPA ;  A9MZR1, SPED_SALPB ;
DR   C0Q5M6, SPED_SALPC ;  B5BL96, SPED_SALPK ;  B4TXL6, SPED_SALSV ;
DR   Q8Z9E3, SPED_SALTI ;  Q8ZRS4, SPED_SALTY ;  A8GJ07, SPED_SERP5 ;
DR   B2U2W9, SPED_SHIB3 ;  Q326B6, SPED_SHIBS ;  Q32K91, SPED_SHIDS ;
DR   Q0T880, SPED_SHIF8 ;  P0A7F8, SPED_SHIFL ;  Q3Z5P0, SPED_SHISS ;
DR   Q2NVS2, SPED_SODGM ;  B4SLE4, SPED_STRM5 ;  B2FKK7, SPED_STRMK ;
DR   Q8PQ44, SPED_XANAC ;  Q3BYB2, SPED_XANC5 ;  Q4UZF5, SPED_XANC8 ;
DR   B0RN02, SPED_XANCB ;  Q9X4I6, SPED_XANCP ;  Q2NYE0, SPED_XANOM ;
DR   B2SL06, SPED_XANOP ;  Q5GV62, SPED_XANOR ;  B2IAF0, SPED_XYLF2 ;
DR   Q9PD40, SPED_XYLFA ;  B0U6Z8, SPED_XYLFM ;  Q87DD1, SPED_XYLFT ;
DR   A1JJM7, SPED_YERE8 ;  A7FM34, SPED_YERP3 ;  Q1C3U6, SPED_YERPA ;
DR   B2K4I1, SPED_YERPB ;  Q8ZBJ7, SPED_YERPE ;  A9R1H5, SPED_YERPG ;
DR   Q1CLX2, SPED_YERPN ;  A4TPU3, SPED_YERPP ;  Q66EH4, SPED_YERPS ;
DR   B1JK46, SPED_YERPY ;  Q81L09, SPEH1_BACAN;  Q817G9, SPEH1_BACCR;
DR   Q633L5, SPEH1_BACCZ;  Q9KDW4, SPEH1_BACHD;  Q81X04, SPEH2_BACAN;
DR   Q815E7, SPEH2_BACCR;  Q631E1, SPEH2_BACCZ;  Q9K859, SPEH2_BACHD;
DR   B7J3Q3, SPEH_ACIF2 ;  B5EL74, SPEH_ACIF5 ;  Q9YED6, SPEH_AERPE ;
DR   B9MLX4, SPEH_ANATD ;  B7GGU7, SPEH_ANOFW ;  O66615, SPEH_AQUAE ;
DR   O28663, SPEH_ARCFU ;  A7Z7I7, SPEH_BACA2 ;  Q72ZF6, SPEH_BACC1 ;
DR   A7GTM8, SPEH_BACCN ;  Q65G98, SPEH_BACLD ;  Q5WEH1, SPEH_BACSK ;
DR   O34426, SPEH_BACSU ;  A9VJP4, SPEH_BACWK ;  C0ZGF5, SPEH_BREBN ;
DR   A4XJ25, SPEH_CALS8 ;  Q3AB53, SPEH_CARHZ ;  A7FYV9, SPEH_CLOB1 ;
DR   C3KUX9, SPEH_CLOB6 ;  A5I788, SPEH_CLOBH ;  C1FM32, SPEH_CLOBJ ;
DR   B1IFK1, SPEH_CLOBK ;  A7GIV2, SPEH_CLOBL ;  B1L242, SPEH_CLOBM ;
DR   B9E1Y4, SPEH_CLOK1 ;  A5N8H9, SPEH_CLOK5 ;  Q895G3, SPEH_CLOTE ;
DR   A3DDC1, SPEH_CLOTH ;  B1YK97, SPEH_EXIS2 ;  C4L466, SPEH_EXISA ;
DR   A7HMP1, SPEH_FERNB ;  Q5KWC6, SPEH_GEOKA ;  C5D646, SPEH_GEOSW ;
DR   B4U6K3, SPEH_HYDS0 ;  Q04NB1, SPEH_LEPBJ ;  Q04WJ1, SPEH_LEPBL ;
DR   Q75FF4, SPEH_LEPIC ;  P0C0A0, SPEH_LEPIN ;  A6UUL6, SPEH_META3 ;
DR   Q57763, SPEH_METJA ;  A4G0Y9, SPEH_METM5 ;  A9A978, SPEH_METM6 ;
DR   A6VHH1, SPEH_METM7 ;  Q6LWX1, SPEH_METMP ;  A6UQM8, SPEH_METVS ;
DR   Q2RIZ3, SPEH_MOOTA ;  A6Q574, SPEH_NITSB ;  Q8CV19, SPEH_OCEIH ;
DR   A5D2A7, SPEH_PELTS ;  C0QRY8, SPEH_PERMH ;  Q6KZI1, SPEH_PICTO ;
DR   A9BCR1, SPEH_PROM4 ;  Q7V9U7, SPEH_PROMA ;  Q7V558, SPEH_PROMM ;
DR   A6VCN1, SPEH_PSEA7 ;  B7V1I5, SPEH_PSEA8 ;  Q02FP9, SPEH_PSEAB ;
DR   Q9HV35, SPEH_PSEAE ;  Q9UXT3, SPEH_PYRAB ;  Q8ZX33, SPEH_PYRAE ;
DR   A4WIJ1, SPEH_PYRAR ;  Q8TZQ6, SPEH_PYRFU ;  O57711, SPEH_PYRHO ;
DR   A1RUV2, SPEH_PYRIL ;  Q5JDS7, SPEH_PYRKO ;  Q4J8J9, SPEH_SULAC ;
DR   C3N6B5, SPEH_SULIA ;  C4KHT0, SPEH_SULIK ;  C3MQJ5, SPEH_SULIL ;
DR   C3MW73, SPEH_SULIM ;  C3NGX1, SPEH_SULIN ;  C3NES3, SPEH_SULIY ;
DR   Q9UWY8, SPEH_SULSO ;  B2V7P6, SPEH_SULSY ;  Q971A0, SPEH_SULTO ;
DR   Q67SD7, SPEH_SYMTH ;  A5GIW2, SPEH_SYNPW ;  Q7U4L7, SPEH_SYNPX ;
DR   Q0AZ53, SPEH_SYNWW ;  B7ICX1, SPEH_THEAB ;  Q9HIY0, SPEH_THEAC ;
DR   C5A3H2, SPEH_THEGJ ;  A6LKI7, SPEH_THEM4 ;  Q9WZC3, SPEH_THEMA ;
DR   B1YCN7, SPEH_THENV ;  B6YV04, SPEH_THEON ;  A5IJD2, SPEH_THEP1 ;
DR   B0K9L2, SPEH_THEP3 ;  B0K199, SPEH_THEPX ;  B9KXN0, SPEH_THERP ;
DR   B1L8F1, SPEH_THESQ ;  Q8RA74, SPEH_THETN ;  Q97BP8, SPEH_THEVO ;
DR   B5YI28, SPEH_THEYD ;
//
ID   4.1.1.51
DE   3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase.
AN   3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-carboxy-lyase.
CA   3-hydroxy-2-methylpyridine-4,5-dicarboxylate = 3-hydroxy-2-
CA   methylpyridine-5-carboxylate + CO(2).
//
ID   4.1.1.52
DE   6-methylsalicylate decarboxylase.
AN   6-methylsalicylate carboxy-lyase.
AN   6-MSA decarboxylase.
CA   6-methylsalicylate = 3-methylphenol + CO(2).
//
ID   4.1.1.53
DE   Phenylalanine decarboxylase.
AN   L-phenylalanine carboxy-lyase.
AN   L-phenylalanine decarboxylase.
CA   L-phenylalanine = phenylethylamine + CO(2).
CF   Pyridoxal 5'-phosphate.
CC   -!- Also acts on tyrosine and other aromatic amino acids.
//
ID   4.1.1.54
DE   Dihydroxyfumarate decarboxylase.
AN   Dihydroxyfumarate carboxy-lyase.
CA   Dihydroxyfumarate = tartronate semialdehyde + CO(2).
//
ID   4.1.1.55
DE   4,5-dihydroxyphthalate decarboxylase.
AN   4,5-dihydroxyphthalate carboxy-lyase.
CA   4,5-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO(2).
DR   Q05185, PHT5_PSEPU ;  Q59727, PHTD_COMTE ;
//
ID   4.1.1.56
DE   3-oxolaurate decarboxylase.
AN   3-oxododecanoate carboxy-lyase.
AN   Beta-ketoacyl decarboxylase.
AN   Beta-ketolaurate decarboxylase.
CA   3-oxododecanoate = 2-undecanone + CO(2).
CC   -!- Also decarboxylates other C(14) to C(16) oxo acids.
//
ID   4.1.1.57
DE   Methionine decarboxylase.
AN   L-methionine carboxy-lyase.
AN   L-methionine decarboxylase.
CA   L-methionine = 3-methylthiopropanamine + CO(2).
//
ID   4.1.1.58
DE   Orsellinate decarboxylase.
AN   Orsellinate carboxy-lyase.
CA   2,4-dihydroxy-6-methylbenzoate = orcinol + CO(2).
//
ID   4.1.1.59
DE   Gallate decarboxylase.
AN   Gallate carboxy-lyase.
AN   Gallic acid decarboxylase.
CA   3,4,5-trihydroxybenzoate = pyrogallol + CO(2).
//
ID   4.1.1.60
DE   Stipitatonate decarboxylase.
CA   Stipitatonate = stipitatate + CO(2).
//
ID   4.1.1.61
DE   4-hydroxybenzoate decarboxylase.
AN   4-hydroxybenzoate carboxy-lyase.
AN   p-hydroxybenzoate decarboxylase.
CA   4-hydroxybenzoate = phenol + CO(2).
DR   P94404, BSDB_BACSU ;  Q9Z8S4, BSDB_CHLPN ;  P94405, BSDC_BACSU ;
DR   Q9Z8L0, BSDC_CHLPN ;  C0H3U9, BSDD_BACSU ;
//
ID   4.1.1.62
DE   Gentisate decarboxylase.
AN   2,5-dihydroxybenzoate decarboxylase.
AN   Gentisate carboxy-lyase.
CA   2,5-dihydroxybenzoate = hydroquinone + CO(2).
//
ID   4.1.1.63
DE   Protocatechuate decarboxylase.
AN   3,4-dihydroxybenzoate decarboxylase.
AN   Protocatechuate carboxy-lyase.
CA   3,4-dihydroxybenzoate = catechol + CO(2).
DR   P86833, DBD34_SEDHY;
//
ID   4.1.1.64
DE   2,2-dialkylglycine decarboxylase (pyruvate).
AN   L-alanine-alpha-ketobutyrate aminotransferase.
CA   2,2-dialkylglycine + pyruvate = dialkyl ketone + CO(2) + L-alanine.
CF   Pyridoxal 5'-phosphate.
CC   -!- Acts on 2-amino-2-methylpropanoate (i.e. 2-methylalanine), 2-amino-2-
CC       methylbutanoate and 1-aminocyclopentanecarboxylate.
PR   PROSITE; PDOC00519;
DR   P16932, DGDA_BURCE ;
//
ID   4.1.1.65
DE   Phosphatidylserine decarboxylase.
AN   Phosphatidyl-L-serine carboxy-lyase.
AN   PS decarboxylase.
CA   Phosphatidyl-L-serine = phosphatidylethanolamine + CO(2).
CF   Pyruvate or pyridoxal 5'-phosphate.
DR   Q58DH2, PISD_BOVIN ;  Q10949, PISD_CAEEL ;  P27465, PISD_CRIGR ;
DR   Q9UG56, PISD_HUMAN ;  Q8BSF4, PISD_MOUSE ;  Q5R8I8, PISD_PONAB ;
DR   Q97N08, PSD1_CLOAB ;  Q9UTB5, PSD1_SCHPO ;  P39006, PSD1_YEAST ;
DR   Q97KW7, PSD2_CLOAB ;  O14333, PSD2_SCHPO ;  P53037, PSD2_YEAST ;
DR   Q6F6W3, PSD_ACIAD  ;  B7GUX2, PSD_ACIB3  ;  B7I242, PSD_ACIB5  ;
DR   B2I1N9, PSD_ACIBC  ;  Q1IP39, PSD_ACIBL  ;  B0VP52, PSD_ACIBS  ;
DR   A3MA23, PSD_ACIBT  ;  B0V9W1, PSD_ACIBY  ;  C1F3M6, PSD_ACIC5  ;
DR   B9MAC0, PSD_ACIET  ;  A3N255, PSD_ACTP2  ;  B3H2F9, PSD_ACTP7  ;
DR   B0BR01, PSD_ACTPJ  ;  B9JC94, PSD_AGRRK  ;  Q8UGH4, PSD_AGRT5  ;
DR   B9JUQ5, PSD_AGRVS  ;  Q0VMD7, PSD_ALCBS  ;  Q0AAC1, PSD_ALHEH  ;
DR   B6EMR5, PSD_ALISL  ;  A8MJ83, PSD_ALKOO  ;  B4S0J5, PSD_ALTMD  ;
DR   B3ESH0, PSD_AMOA5  ;  B8JBF7, PSD_ANAD2  ;  Q5PB25, PSD_ANAMM  ;
DR   Q2GKG5, PSD_ANAPZ  ;  B4UEL4, PSD_ANASK  ;  B7GKA2, PSD_ANOFW  ;
DR   O28234, PSD_ARCFU  ;  Q5NXP3, PSD_AROAE  ;  A8HXJ6, PSD_AZOC5  ;
DR   B6YRI1, PSD_AZOPC  ;  A1KBF9, PSD_AZOSB  ;  C1DLP2, PSD_AZOVD  ;
DR   Q44558, PSD_AZOVI  ;  C3P929, PSD_BACAA  ;  C3L5U2, PSD_BACAC  ;
DR   A0RIV4, PSD_BACAH  ;  Q81LP7, PSD_BACAN  ;  B7JNX0, PSD_BACC0  ;
DR   Q730J7, PSD_BACC1  ;  B7IYJ1, PSD_BACC2  ;  C1ESN2, PSD_BACC3  ;
DR   B7HCW5, PSD_BACC4  ;  B7HPN7, PSD_BACC7  ;  A7GT32, PSD_BACCN  ;
DR   Q818C6, PSD_BACCR  ;  Q634K5, PSD_BACCZ  ;  Q5LHJ3, PSD_BACFN  ;
DR   Q64YG8, PSD_BACFR  ;  Q9KDA3, PSD_BACHD  ;  Q6HDI5, PSD_BACHK  ;
DR   P39822, PSD_BACSU  ;  Q8A5K8, PSD_BACTN  ;  A6L1J5, PSD_BACV8  ;
DR   A9VHW5, PSD_BACWK  ;  A1US45, PSD_BARBK  ;  Q6G5G6, PSD_BARHE  ;
DR   Q6G070, PSD_BARQU  ;  A9IRR6, PSD_BART1  ;  Q1LSP9, PSD_BAUCH  ;
DR   B2IC55, PSD_BEII9  ;  Q7VQP8, PSD_BLOFL  ;  Q493W4, PSD_BLOPB  ;
DR   Q2L0K8, PSD_BORA1  ;  Q7WIF7, PSD_BORBR  ;  Q7W6I5, PSD_BORPA  ;
DR   A9IM91, PSD_BORPD  ;  Q7VYM4, PSD_BORPE  ;  Q89NP2, PSD_BRAJA  ;
DR   A5EHF4, PSD_BRASB  ;  A4YWZ6, PSD_BRASO  ;  C0Z4E2, PSD_BREBN  ;
DR   B2S9U3, PSD_BRUA1  ;  Q2YMI0, PSD_BRUA2  ;  Q57ES4, PSD_BRUAB  ;
DR   A9M8W7, PSD_BRUC2  ;  C0RHF0, PSD_BRUMB  ;  Q8YFM9, PSD_BRUME  ;
DR   A5VP16, PSD_BRUO2  ;  B0CKC7, PSD_BRUSI  ;  Q8G285, PSD_BRUSU  ;
DR   B1YTR9, PSD_BURA4  ;  Q1BV00, PSD_BURCA  ;  B1JVQ3, PSD_BURCC  ;
DR   A0K936, PSD_BURCH  ;  B4E5N4, PSD_BURCJ  ;  Q0BDB7, PSD_BURCM  ;
DR   A9AJN2, PSD_BURM1  ;  A3MI88, PSD_BURM7  ;  Q62IM1, PSD_BURMA  ;
DR   A1V2K3, PSD_BURMS  ;  A3NT92, PSD_BURP0  ;  Q3JUC1, PSD_BURP1  ;
DR   A3N7K5, PSD_BURP6  ;  B2JDN8, PSD_BURP8  ;  B2T2D2, PSD_BURPP  ;
DR   Q63VP5, PSD_BURPS  ;  Q39ED3, PSD_BURS3  ;  Q2SZP7, PSD_BURTA  ;
DR   A4JGE2, PSD_BURVG  ;  Q142I5, PSD_BURXL  ;  Q9PP76, PSD_CAMJE  ;
DR   Q3ADL6, PSD_CARHZ  ;  Q5L4W1, PSD_CHLAB  ;  Q3APS7, PSD_CHLCH  ;
DR   Q821L3, PSD_CHLCV  ;  Q256C9, PSD_CHLFF  ;  B3EH32, PSD_CHLL2  ;
DR   Q9PLM7, PSD_CHLMU  ;  B3QM38, PSD_CHLP8  ;  B3EMS8, PSD_CHLPB  ;
DR   A1BE07, PSD_CHLPD  ;  Q9Z767, PSD_CHLPN  ;  B0B8S5, PSD_CHLT2  ;
DR   B3QU02, PSD_CHLT3  ;  Q3KKZ5, PSD_CHLTA  ;  B0BAF4, PSD_CHLTB  ;
DR   Q93SU4, PSD_CHLTE  ;  P0CD79, PSD_CHLTR  ;  Q1QUI2, PSD_CHRSD  ;
DR   Q7P0H6, PSD_CHRVO  ;  A8AMN8, PSD_CITK8  ;  A7FQ59, PSD_CLOB1  ;
DR   C3KXS2, PSD_CLOB6  ;  A6LPC8, PSD_CLOB8  ;  B2UX63, PSD_CLOBA  ;
DR   B2THF2, PSD_CLOBB  ;  A5HXS0, PSD_CLOBH  ;  C1FPI8, PSD_CLOBJ  ;
DR   A7G9C7, PSD_CLOBL  ;  B1L1M1, PSD_CLOBM  ;  B8I6U9, PSD_CLOCE  ;
DR   B9DXW5, PSD_CLOK1  ;  A5N497, PSD_CLOK5  ;  A0Q3R9, PSD_CLONN  ;
DR   Q0TV39, PSD_CLOP1  ;  Q46192, PSD_CLOPA  ;  Q8XPD5, PSD_CLOPE  ;
DR   Q0SWT6, PSD_CLOPS  ;  Q899T7, PSD_CLOTE  ;  Q47VZ2, PSD_COLP3  ;
DR   B6J9C5, PSD_COXB1  ;  B6J316, PSD_COXB2  ;  A9KEZ8, PSD_COXBN  ;
DR   A9NAS0, PSD_COXBR  ;  Q83AQ4, PSD_COXBU  ;  Q0KCU1, PSD_CUPNH  ;
DR   Q473V4, PSD_CUPPJ  ;  B3R3V5, PSD_CUPTR  ;  Q11Y69, PSD_CYTH3  ;
DR   Q47C25, PSD_DECAR  ;  A9C3H8, PSD_DELAS  ;  B8J4F6, PSD_DESDA  ;
DR   Q30WD6, PSD_DESDG  ;  B8FQ96, PSD_DESHD  ;  Q24UV7, PSD_DESHY  ;
DR   C4XPA6, PSD_DESMR  ;  Q6AJI0, PSD_DESPS  ;  Q726X7, PSD_DESVH  ;
DR   Q9EV04, PSD_DICD3  ;  A8LIK6, PSD_DINSH  ;  A7ZV31, PSD_ECO24  ;
DR   B7UPY0, PSD_ECO27  ;  B7MKW7, PSD_ECO45  ;  B7LC21, PSD_ECO55  ;
DR   P0A8K3, PSD_ECO57  ;  B5Z2G9, PSD_ECO5E  ;  B7NTL9, PSD_ECO7I  ;
DR   B7MSX5, PSD_ECO81  ;  B7M8S3, PSD_ECO8A  ;  C5A1F4, PSD_ECOBW  ;
DR   B1XDR4, PSD_ECODH  ;  A8A7Q7, PSD_ECOHS  ;  Q0T9N1, PSD_ECOL5  ;
DR   P0A8K2, PSD_ECOL6  ;  B1IT43, PSD_ECOLC  ;  P0A8K1, PSD_ECOLI  ;
DR   B7NG97, PSD_ECOLU  ;  B6I267, PSD_ECOSE  ;  B1LQI3, PSD_ECOSM  ;
DR   Q1R397, PSD_ECOUT  ;  Q3YSG2, PSD_EHRCJ  ;  Q2GG56, PSD_EHRCR  ;
DR   Q5FHJ9, PSD_EHRRG  ;  Q5HBL4, PSD_EHRRW  ;  A7MMA5, PSD_ENTS8  ;
DR   Q6D035, PSD_ERWCT  ;  B2VCV2, PSD_ERWT9  ;  Q2NBU9, PSD_ERYLH  ;
DR   B7LLU4, PSD_ESCF3  ;  B0TZM7, PSD_FRAP2  ;  Q14J65, PSD_FRAT1  ;
DR   A7NAF0, PSD_FRATF  ;  Q2A4Y0, PSD_FRATH  ;  B2SFB2, PSD_FRATM  ;
DR   A0Q562, PSD_FRATN  ;  Q0BN99, PSD_FRATO  ;  Q5NHR3, PSD_FRATT  ;
DR   A4IZN0, PSD_FRATW  ;  Q8RGF2, PSD_FUSNN  ;  B5EHU9, PSD_GEOBB  ;
DR   Q5KWX3, PSD_GEOKA  ;  B3E5X3, PSD_GEOLS  ;  Q39W75, PSD_GEOMG  ;
DR   B9M5B0, PSD_GEOSF  ;  Q74BX0, PSD_GEOSL  ;  C6E524, PSD_GEOSM  ;
DR   C5D4W6, PSD_GEOSW  ;  A5G7V2, PSD_GEOUR  ;  A9H1G5, PSD_GLUDA  ;
DR   Q5FU81, PSD_GLUOX  ;  Q0BVB3, PSD_GRABC  ;  Q7VNA7, PSD_HAEDU  ;
DR   Q4QP27, PSD_HAEI8  ;  P43789, PSD_HAEIN  ;  B8F658, PSD_HAEPS  ;
DR   Q0I4T3, PSD_HAES1  ;  B0UWL4, PSD_HAES2  ;  Q2SBA8, PSD_HAHCH  ;
DR   A1WV88, PSD_HALHL  ;  Q9HN46, PSD_HALSA  ;  C4K3T9, PSD_HAMD5  ;
DR   B6JNM7, PSD_HELP2  ;  Q1CRQ1, PSD_HELPH  ;  Q9ZJN0, PSD_HELPJ  ;
DR   B2UVC1, PSD_HELPS  ;  O25911, PSD_HELPY  ;  A4G529, PSD_HERAR  ;
DR   Q5QVW0, PSD_IDILO  ;  B5Y342, PSD_KLEP3  ;  A6TH77, PSD_KLEP7  ;
DR   Q1MQ97, PSD_LAWIP  ;  Q5X0Q0, PSD_LEGPA  ;  A5IIH5, PSD_LEGPC  ;
DR   Q5ZRA9, PSD_LEGPH  ;  Q5WSH5, PSD_LEGPL  ;  Q2W9R7, PSD_MAGSA  ;
DR   A0L627, PSD_MAGSM  ;  Q65RD9, PSD_MANSM  ;  A1U4D6, PSD_MARAV  ;
DR   Q11JQ0, PSD_MESSB  ;  Q8TUF2, PSD_METAC  ;  Q46E43, PSD_METBF  ;
DR   Q12U14, PSD_METBU  ;  Q608T0, PSD_METCA  ;  Q1GZE8, PSD_METFK  ;
DR   Q58227, PSD_METJA  ;  Q8TYX9, PSD_METKA  ;  Q8PX20, PSD_METMA  ;
DR   A2SJL1, PSD_METPP  ;  B8EMY8, PSD_METSB  ;  O27105, PSD_METTH  ;
DR   A0QLQ2, PSD_MYCA1  ;  B1MH53, PSD_MYCA9  ;  P67548, PSD_MYCBO  ;
DR   A1KFQ9, PSD_MYCBP  ;  C1AKB3, PSD_MYCBT  ;  A4T2V6, PSD_MYCGI  ;
DR   B8ZUA0, PSD_MYCLB  ;  Q9CCW9, PSD_MYCLE  ;  B2HQP4, PSD_MYCMM  ;
DR   Q73SZ2, PSD_MYCPA  ;  A0QQS6, PSD_MYCS2  ;  A3PU20, PSD_MYCSJ  ;
DR   A1UAG5, PSD_MYCSK  ;  Q1BEG9, PSD_MYCSS  ;  A5TZG3, PSD_MYCTA  ;
DR   P67547, PSD_MYCTU  ;  A0PNL2, PSD_MYCUA  ;  A1T339, PSD_MYCVP  ;
DR   Q1D614, PSD_MYXXD  ;  Q5F7H2, PSD_NEIG1  ;  B4RJK0, PSD_NEIG2  ;
DR   Q50967, PSD_NEIGO  ;  A9M4G3, PSD_NEIM0  ;  Q9JUS3, PSD_NEIMA  ;
DR   Q9JZP0, PSD_NEIMB  ;  A1KTN1, PSD_NEIMF  ;  Q2GEF4, PSD_NEOSM  ;
DR   Q0AGM1, PSD_NITEC  ;  Q82UZ4, PSD_NITEU  ;  Q1QN82, PSD_NITHX  ;
DR   Q2YB83, PSD_NITMU  ;  Q3J754, PSD_NITOC  ;  Q3ST95, PSD_NITWN  ;
DR   Q5YNV8, PSD_NOCFA  ;  Q2G8L3, PSD_NOVAD  ;  A6WWD3, PSD_OCHA4  ;
DR   B6JHT1, PSD_OLICO  ;  A6LF25, PSD_PARD8  ;  A7HS52, PSD_PARL1  ;
DR   Q9CJU2, PSD_PASMU  ;  Q3A3A8, PSD_PELCD  ;  Q3B2G7, PSD_PELLD  ;
DR   B4SE07, PSD_PELPB  ;  A1AS38, PSD_PELPD  ;  Q4FMX4, PSD_PELUB  ;
DR   Q7MYS6, PSD_PHOLL  ;  Q6LM21, PSD_PHOPR  ;  A1VUQ1, PSD_POLNA  ;
DR   Q121P6, PSD_POLSJ  ;  A4SXR2, PSD_POLSQ  ;  B2RJF8, PSD_PORG3  ;
DR   Q7MVS5, PSD_PORGI  ;  B4S5J9, PSD_PROA2  ;  A4SG02, PSD_PROVI  ;
DR   Q15Q53, PSD_PSEA6  ;  A6VD70, PSD_PSEA7  ;  B7V346, PSD_PSEA8  ;
DR   Q02F61, PSD_PSEAB  ;  Q9HUK8, PSD_PSEAE  ;  Q1I433, PSD_PSEE4  ;
DR   Q4KJ87, PSD_PSEF5  ;  C3KDM6, PSD_PSEFS  ;  Q3IFN3, PSD_PSEHT  ;
DR   A4XPX3, PSD_PSEMY  ;  A5W9U4, PSD_PSEP1  ;  Q3KJ03, PSD_PSEPF  ;
DR   B0KL10, PSD_PSEPG  ;  Q88DB9, PSD_PSEPK  ;  B1JAE9, PSD_PSEPW  ;
DR   A4VR22, PSD_PSEU5  ;  Q4FQD5, PSD_PSYA2  ;  Q1Q8K8, PSD_PSYCK  ;
DR   A1SZV9, PSD_PSYIN  ;  Q1LPX5, PSD_RALME  ;  B2U7S2, PSD_RALPJ  ;
DR   Q8XXN9, PSD_RALSO  ;  B3PUR0, PSD_RHIE6  ;  Q2KAC2, PSD_RHIEC  ;
DR   Q1MJ32, PSD_RHIL3  ;  Q984W0, PSD_RHILO  ;  B5ZW97, PSD_RHILW  ;
DR   Q9FDI9, PSD_RHIME  ;  C3M997, PSD_RHISN  ;  Q7UTK9, PSD_RHOBA  ;
DR   C0ZUI0, PSD_RHOE4  ;  Q221E5, PSD_RHOFD  ;  C1B0C2, PSD_RHOOB  ;
DR   Q2IUP7, PSD_RHOP2  ;  Q07Q32, PSD_RHOP5  ;  Q6N898, PSD_RHOPA  ;
DR   Q216N7, PSD_RHOPB  ;  Q139C9, PSD_RHOPS  ;  B3QCT3, PSD_RHOPT  ;
DR   Q2RNB6, PSD_RHORT  ;  A3PMB0, PSD_RHOS1  ;  Q3IZY9, PSD_RHOS4  ;
DR   A4WVB2, PSD_RHOS5  ;  B9KLR2, PSD_RHOSK  ;  Q0SES0, PSD_RHOSR  ;
DR   C3PMT8, PSD_RICAE  ;  A8GMN9, PSD_RICAH  ;  A8GW88, PSD_RICB8  ;
DR   Q1RHW4, PSD_RICBR  ;  A8EXZ0, PSD_RICCK  ;  Q92IU5, PSD_RICCN  ;
DR   Q4UKN0, PSD_RICFE  ;  Q9ZDT4, PSD_RICPR  ;  C4K0V0, PSD_RICPU  ;
DR   B0BWR2, PSD_RICRO  ;  A8GRB1, PSD_RICRS  ;  Q68XC8, PSD_RICTY  ;
DR   Q21H90, PSD_SACD2  ;  A4F743, PSD_SACEN  ;  B5F377, PSD_SALA4  ;
DR   A9MFQ0, PSD_SALAR  ;  Q57GM9, PSD_SALCH  ;  B5FRL8, PSD_SALDC  ;
DR   B5R023, PSD_SALEP  ;  B5R9A9, PSD_SALG2  ;  B4TF96, PSD_SALHS  ;
DR   B4T2Q7, PSD_SALNS  ;  Q5PLG9, PSD_SALPA  ;  A9N419, PSD_SALPB  ;
DR   C0Q6C0, PSD_SALPC  ;  B5BKH1, PSD_SALPK  ;  Q2S3Y8, PSD_SALRD  ;
DR   B4TSE2, PSD_SALSV  ;  Q8Z194, PSD_SALTI  ;  Q8ZKB1, PSD_SALTY  ;
DR   A1SA30, PSD_SHEAM  ;  B8ECB2, PSD_SHEB2  ;  A3D015, PSD_SHEB5  ;
DR   A6WSW1, PSD_SHEB8  ;  A9L3W8, PSD_SHEB9  ;  Q12J86, PSD_SHEDO  ;
DR   Q07XV9, PSD_SHEFN  ;  B0TU73, PSD_SHEHH  ;  A3QAD1, PSD_SHELP  ;
DR   A8H8H5, PSD_SHEPA  ;  A4YAL8, PSD_SHEPC  ;  A0KSQ8, PSD_SHESA  ;
DR   A8FRC6, PSD_SHESH  ;  Q0HMP8, PSD_SHESM  ;  Q0HR33, PSD_SHESR  ;
DR   A1RFQ8, PSD_SHESW  ;  B1KHV8, PSD_SHEWM  ;  B2TY38, PSD_SHIB3  ;
DR   Q31T93, PSD_SHIBS  ;  Q328E0, PSD_SHIDS  ;  Q0SXB9, PSD_SHIF8  ;
DR   P0A8K4, PSD_SHIFL  ;  Q3YUI0, PSD_SHISS  ;  Q5LKT7, PSD_SILPO  ;
DR   Q1GMQ8, PSD_SILST  ;  A6U7E9, PSD_SINMW  ;  Q2NW88, PSD_SODGM  ;
DR   Q027V0, PSD_SOLUE  ;  Q1GRP7, PSD_SPHAL  ;  Q82LU4, PSD_STRAW  ;
DR   Q9ZBK6, PSD_STRCO  ;  B1VV20, PSD_STRGG  ;  B4SQW4, PSD_STRM5  ;
DR   B2FP04, PSD_STRMK  ;  Q67NP3, PSD_SYMTH  ;  Q2LTR6, PSD_SYNAS  ;
DR   Q47NP2, PSD_THEFY  ;  Q31H64, PSD_THICR  ;  Q3SHE5, PSD_THIDA  ;
DR   C5CU16, PSD_VARPS  ;  A1WIF0, PSD_VEREI  ;  A5F3N7, PSD_VIBC3  ;
DR   Q9KV19, PSD_VIBCH  ;  C3LR71, PSD_VIBCM  ;  Q5E2C0, PSD_VIBF1  ;
DR   B5FBS2, PSD_VIBFM  ;  A7MZ50, PSD_VIBHB  ;  Q87KZ9, PSD_VIBPA  ;
DR   Q8DCV8, PSD_VIBVU  ;  Q7MGZ5, PSD_VIBVY  ;  Q8D2C6, PSD_WIGBR  ;
DR   Q73GB0, PSD_WOLPM  ;  Q5GSL0, PSD_WOLTR  ;  C0R4E0, PSD_WOLWR  ;
DR   Q8PJ17, PSD_XANAC  ;  Q3BRK2, PSD_XANC5  ;  Q4UWE4, PSD_XANC8  ;
DR   B0RR72, PSD_XANCB  ;  Q8P7Q6, PSD_XANCP  ;  Q2P0T0, PSD_XANOM  ;
DR   Q5GXQ3, PSD_XANOR  ;  A7IPD6, PSD_XANP2  ;  B2I9I2, PSD_XYLF2  ;
DR   Q9PDL4, PSD_XYLFA  ;  B0U6J7, PSD_XYLFM  ;  Q87DS7, PSD_XYLFT  ;
DR   A1JIQ6, PSD_YERE8  ;  A7FMY9, PSD_YERP3  ;  Q1C0Z1, PSD_YERPA  ;
DR   B2K1Z5, PSD_YERPB  ;  Q8ZIX1, PSD_YERPE  ;  A9QYP0, PSD_YERPG  ;
DR   Q1CEE6, PSD_YERPN  ;  A4TRP9, PSD_YERPP  ;  Q66FC4, PSD_YERPS  ;
DR   B1JMP9, PSD_YERPY  ;  Q9X5E3, PSD_ZYMMO  ;
//
ID   4.1.1.66
DE   Uracil-5-carboxylate decarboxylase.
AN   Uracil-5-carboxylate carboxy-lyase.
AN   Uracil-5-carboxylic acid decarboxylase.
CA   Uracil 5-carboxylate = uracil + CO(2).
//
ID   4.1.1.67
DE   UDP-galacturonate decarboxylase.
AN   UDP-D-galacturonate carboxy-lyase.
CA   UDP-D-galacturonate = UDP-L-arabinose + CO(2).
//
ID   4.1.1.68
DE   5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase.
AN   5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase.
CA   5-oxopent-3-ene-1,2,5-tricarboxylate = 2-oxohept-3-enedioate + CO(2).
DR   Q46978, HPAG_ECOLX ;  Q9RPU5, HPAG_SALDU ;  P37352, HPCE_ECOLX ;
//
ID   4.1.1.69
DE   3,4-dihydroxyphthalate decarboxylase.
AN   3,4-dihydroxyphthalate carboxy-lyase.
CA   3,4-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO(2).
//
ID   4.1.1.70
DE   Glutaconyl-CoA decarboxylase.
AN   4-carboxybut-2-enoyl-CoA carboxy-lyase.
AN   Glutaconyl coenzyme A decarboxylase.
AN   Pent-2-enoyl-CoA carboxy-lyase.
CA   4-carboxybut-2-enoyl-CoA = but-2-enoyl-CoA + CO(2).
CF   Biotin.
CC   -!- The enzyme from Acidaminococcus fermentans is a biotinyl-protein,
CC       requires sodium, and acts as a sodium pump.
CC   -!- Prior to the sodium dependent decarboxylation, the carboxylate is
CC       transferred to biotin in a sodium independent manner.
PR   PROSITE; PDOC00167;
PR   PROSITE; PDOC50980;
DR   Q06700, GCDA_ACIFV ;  Q9ZAA6, GCDB_ACIFV ;  Q9ZAA7, GCDC_ACIFV ;
DR   Q9ZAA8, GCDD_ACIFV ;
//
ID   4.1.1.71
DE   2-oxoglutarate decarboxylase.
AN   2-oxoglutarate carboxy-lyase.
AN   Alpha-ketoglutarate decarboxylase.
CA   2-oxoglutarate = succinate semialdehyde + CO(2).
CF   Thiamine diphosphate.
CC   -!- Highly specific.
DR   Q7U0A6, KGD_MYCBO  ;  A1KI36, KGD_MYCBP  ;  Q9CC97, KGD_MYCLE  ;
DR   Q73WX4, KGD_MYCPA  ;  A0R2B1, KGD_MYCS2  ;  A3Q3N5, KGD_MYCSJ  ;
DR   A1UK81, KGD_MYCSK  ;  Q1B4V6, KGD_MYCSS  ;  A5U1U6, KGD_MYCTA  ;
DR   O50463, KGD_MYCTU  ;  A0PVU7, KGD_MYCUA  ;  A1TDK2, KGD_MYCVP  ;
//
ID   4.1.1.72
DE   Branched-chain-2-oxoacid decarboxylase.
AN   (3S)-3-methyl-2-oxopentanoate carboxy-lyase.
CA   (3S)-3-methyl-2-oxopentanoate = 2-methylbutanal + CO(2).
CC   -!- Acts on a number of 2-oxo acids, with a high affinity toward
CC       branched-chain substrates.
CC   -!- The aldehyde formed may be enzyme-bound, and may be an intermediate
CC       in the bacterial system for biosynthesis of branched-chain fatty
CC       acids.
//
ID   4.1.1.73
DE   Tartrate decarboxylase.
AN   (R,R)-tartrate carboxy-lyase.
CA   (R,R)-tartrate = D-glycerate + CO(2).
DR   Q44471, TTUC1_AGRVI;  P70787, TTUC2_AGRVI;  O34296, TTUC3_AGRVI;
DR   P70792, TTUC4_AGRVI;  O34295, TTUC5_AGRVI;  P42958, TTUC_BACSU ;
DR   Q51945, TTUC_PSEPU ;
//
ID   4.1.1.74
DE   Indolepyruvate decarboxylase.
AN   3-(indol-3-yl)pyruvate carboxy-lyase.
AN   Indol-3-yl-pyruvate carboxy-lyase.
AN   Indole-3-pyruvate decarboxylase.
CA   3-(indol-3-yl)pyruvate = 2-(indol-3-yl)acetaldehyde + CO(2).
CF   Magnesium; Thiamine diphosphate.
CC   -!- More specific than EC 4.1.1.1.
PR   PROSITE; PDOC00166;
DR   P51852, DCIP_AZOBR ;  P23234, DCIP_ENTCL ;
//
ID   4.1.1.75
DE   5-guanidino-2-oxopentanoate decarboxylase.
AN   2-oxo-5-guanidinopentanoate carboxy-lyase.
AN   2-oxo-5-guanidinopentanoate decarboxylase.
AN   2-oxo-5-guanidinovalerate alpha-ketoarginine decarboxylase.
CA   5-guanidino-2-oxo-pentanoate = 4-guanidinobutanal + CO(2).
CF   Divalent cation; Thiamine diphosphate.
//
ID   4.1.1.76
DE   Arylmalonate decarboxylase.
AN   2-aryl-2-methylmalonate carboxy-lyase.
AN   AMDase.
CA   2-aryl-2-methylmalonate = 2-arylpropanoate + CO(2).
DR   Q05115, AMDA_BORBR ;
//
ID   4.1.1.77
DE   4-oxalocrotonate decarboxylase.
AN   4-oxalocrotonate carboxy-lyase.
CA   4-oxalocrotonate = 2-oxopent-4-enoate + CO(2).
CC   -!- Involved in the meta-cleavage pathway for the degradation of phenols,
CC       methylphenols and catechols.
DR   Q9KWS3, AMNE_PSESP ;  P49156, DMPH_PSEUF ;  P49155, XYLI_PSEPU ;
//
ID   4.1.1.78
DE   Acetylenedicarboxylate decarboxylase.
AN   Acetylenedicarboxylate carboxy-lyase.
AN   Acetylenedicarboxylate hydratase.
CA   Acetylenedicarboxylate + H(2)O = pyruvate + CO(2).
CC   -!- The mechanism appears to involve hydration of the acetylene and
CC       decarboxylation of the oxaloacetic acid formed, although free
CC       oxaloacetate is not an intermediate.
CC   -!- It is thus analogous to EC 4.2.1.71 in its mechanism.
CC   -!- Formerly EC 4.2.1.72.
//
ID   4.1.1.79
DE   Sulfopyruvate decarboxylase.
AN   Sulfopyruvate carboxy-lyase.
CA   3-sulfopyruvate = 2-sulfoacetaldehyde + CO(2).
CF   Thiamine diphosphate.
CC   -!- Does not decarboxylate pyruvate or phosphonopyruvate.
CC   -!- The enzyme appears to be oxygen-sensitive.
DR   Q8TKU6, COMDE_METAC;  P58415, COMD_METJA ;  O27274, COMD_METTH ;
DR   P58416, COME_METJA ;
//
ID   4.1.1.80
DE   4-hydroxyphenylpyruvate decarboxylase.
AN   4-hydroxyphenylpyruvate carboxy-lyase.
CA   4-hydroxyphenylpyruvate = 4-hydroxyphenylacetaldehyde + CO(2).
CC   -!- Reacts with dopamine to give the benzylisoquinoline alkaloid
CC       skeleton.
//
ID   4.1.1.81
DE   Threonine-phosphate decarboxylase.
AN   L-threonine O-3-phosphate carboxy-lyase.
AN   L-threonine-O-3-phosphate decarboxylase.
CA   L-threonine O-3-phosphate = (R)-1-aminopropan-2-yl phosphate + CO(2).
CF   Pyridoxal 5'-phosphate.
CC   -!- Unable to decarboxylate the D-isomer of threonine O-3-phosphate.
CC   -!- The product of this reaction, (R)-1-aminopropan-2-yl phosphate,
CC       is the substrate of EC 6.3.1.10, which converts adenosylcobyric acid
CC       into adenosylcobinamide phosphate in the anaerobic cobalamin
CC       biosynthesis pathway.
DR   Q9I468, COBC_PSEAE ;  P21633, COBC_PSEDE ;  Q8EXQ7, COBDQ_LEPIN;
DR   Q8Z8H8, COBD_SALTI ;  P97084, COBD_SALTY ;  Q8R5U4, COBD_THETN ;
//
ID   4.1.1.82
DE   Phosphonopyruvate decarboxylase.
AN   3-phosphonopyruvate carboxy-lyase.
CA   3-phosphonopyruvate = 2-phosphonoacetaldehyde + CO(2).
CF   Magnesium; Thiamine diphosphate.
CC   -!- Catalyzes a step in the biosynthetic pathway of
CC       2-aminoethylphosphonate, a component of the capsular polysaccharide
CC       complex of Bacteroides fragilis.
CC   -!- Activated by the divalent cations Mg(2+), Ca(2+) and Mn(2+).
CC   -!- Pyruvate and sulfopyruvate can also act as substrates, but more
CC       slowly.
PR   PROSITE; PDOC00166;
DR   Q54271, PPD_STRHY  ;  O86938, PPD_STRVR  ;
//
ID   4.1.1.83
DE   4-hydroxyphenylacetate decarboxylase.
AN   4-Hpd.
AN   4-hydroxyphenylacetate carboxy-lyase.
AN   p-Hpd.
AN   p-hydroxyphenylacetate decarboxylase.
CA   (4-hydroxyphenyl)acetate = 4-methylphenol + CO(2).
CC   -!- The enzyme, from the strict anaerobe Clostridium difficile, can also
CC       use (3,4-dihydroxyphenyl)acetate as a substrate, yielding
CC       4-methylcatechol as a product.
CC   -!- The enzyme is a glycyl radical enzyme.
DR   Q18CP5, HPDL_CLOD6 ;  C9XIS5, HPDL_CLODC ;  Q84F16, HPDL_CLODI ;
DR   C9YHW1, HPDL_CLODR ;  Q38HX4, HPDL_CLOSL ;  Q18CP4, HPDS_CLOD6 ;
DR   C9XIS6, HPDS_CLODC ;  Q84F15, HPDS_CLODI ;  C9YHW2, HPDS_CLODR ;
DR   Q38HX3, HPDS_CLOSL ;
//
ID   4.1.1.84
DE   D-dopachrome decarboxylase.
AN   D-dopachrome carboxy-lyase.
AN   D-dopachrome tautomerase.
AN   D-tautomerase.
AN   Phenylpyruvate tautomerase II.
CA   D-dopachrome = 5,6-dihydroxyindole + CO(2).
CC   -!- Specific for D-dopachrome as substrate.
CC   -!- L-dopachrome, L- or D-alpha-methyldopachrome and dopaminochrome do
CC       not act as substrates (see also EC 5.3.3.12).
PR   PROSITE; PDOC00892;
DR   Q68FI3, DOPDA_XENLA;  Q640C5, DOPDB_XENLA;  A5PK65, DOPD_BOVIN ;
DR   Q5ZMG0, DOPD_CHICK ;  P30046, DOPD_HUMAN ;  O35215, DOPD_MOUSE ;
DR   P80254, DOPD_RAT   ;  Q28J83, DOPD_XENTR ;
//
ID   4.1.1.85
DE   3-dehydro-L-gulonate-6-phosphate decarboxylase.
AN   3-dehydro-L-gulonate-6-phosphate carboxy-lyase.
AN   3-keto-L-gulonate 6-phosphate decarboxylase.
AN   KGPDC.
CA   3-dehydro-L-gulonate 6-phosphate = L-xylulose 5-phosphate + CO(2).
CF   Magnesium.
CC   -!- Along with EC 5.1.3.22, this enzyme is involved in a pathway for the
CC       utilization of L-ascorbate by Escherichia coli.
DR   P37678, SGBH_ECOLI ;  P44988, SGBH_HAEIN ;  A7ZV66, ULAD_ECO24 ;
DR   B7UQK5, ULAD_ECO27 ;  B7MLK1, ULAD_ECO45 ;  B7LCQ5, ULAD_ECO55 ;
DR   Q8XDI7, ULAD_ECO57 ;  B5Z2K2, ULAD_ECO5E ;  B7NTQ2, ULAD_ECO7I ;
DR   B7MT10, ULAD_ECO81 ;  B7M8V6, ULAD_ECO8A ;  C4ZR73, ULAD_ECOBW ;
DR   B1XDU7, ULAD_ECODH ;  A8A7U2, ULAD_ECOHS ;  Q0T9J7, ULAD_ECOL5 ;
DR   Q8FAI9, ULAD_ECOL6 ;  B1IT10, ULAD_ECOLC ;  P39304, ULAD_ECOLI ;
DR   B7NGD0, ULAD_ECOLU ;  B6I2A1, ULAD_ECOSE ;  B1LQL6, ULAD_ECOSM ;
DR   B7LLX8, ULAD_ESCF3 ;  P75293, ULAD_MYCPN ;  B5F3B2, ULAD_SALA4 ;
DR   Q57GJ6, ULAD_SALCH ;  B5FS97, ULAD_SALDC ;  B5R0R3, ULAD_SALEP ;
DR   B5R9E3, ULAD_SALG2 ;  B4TFD0, ULAD_SALHS ;  B4T3E7, ULAD_SALNS ;
DR   Q5PJ63, ULAD_SALPA ;  A9N512, ULAD_SALPB ;  B5BKK4, ULAD_SALPK ;
DR   B4TT28, ULAD_SALSV ;  Q8Z169, ULAD_SALTI ;  Q8ZK87, ULAD_SALTY ;
DR   B2TY68, ULAD_SHIB3 ;  Q31TC7, ULAD_SHIBS ;  Q328K1, ULAD_SHIDS ;
DR   Q0SX89, ULAD_SHIF8 ;  Q83P27, ULAD_SHIFL ;  Q3YUF2, ULAD_SHISS ;
//
ID   4.1.1.86
DE   Diaminobutyrate decarboxylase.
AN   DABA DC.
AN   L-2,4-diaminobutanoate carboxy-lyase.
AN   L-2,4-diaminobutyrate decarboxylase.
CA   L-2,4-diaminobutanoate = propane-1,3-diamine + CO(2).
CF   Divalent cation; Pyridoxal 5'-phosphate.
CC   -!- N(4)-acetyl-L-2,4-diaminobutanoate, 2,3-diaminopropanoate, ornithine
CC       and lysine are not substrates.
CC   -!- In Acinetobacter baumannii it is cotranscribed with the neighboring
CC       dat gene that encodes EC 2.6.1.76, which can supply the substrate for
CC       the decarboxylase.
DR   Q43908, DDC_ACIBA  ;  P71362, DDC_HAEIN  ;  Q9Z3R1, RHBB_RHIME ;
//
ID   4.1.1.87
DE   Malonyl-S-ACP decarboxylase.
AN   Malonyl-S-acyl-carrier protein decarboxylase.
CA   A malonyl-[acyl-carrier protein] + H(+) = an acetyl-[acyl-carrier
CA   protein] + CO(2).
CC   -!- This enzyme comprises the beta and gamma subunits of EC 4.1.1.88 but
CC       is not present in EC 4.1.1.89.
CC   -!- It follows on from EC 2.3.1.187 and results in the regeneration of
CC       the acetylated form of the acyl-carrier-protein subunit of malonate
CC       decarboxylase.
CC   -!- The carboxy group is lost with retention of configuration.
DR   P40804, PKSF_BACSU ;
//
ID   4.1.1.88
DE   Biotin-independent malonate decarboxylase.
AN   Malonate carboxy-lyase (biotin-independent).
AN   Malonate decarboxylase.
AN   MDC.
CA   Malonate + H(+) = acetate + CO(2).
CC   -!- Two types of malonate decarboxylase are currently known, both of
CC       which form multienzyme complexes.
CC   -!- This enzyme is a cytosolic protein that is biotin-independent.
CC   -!- The other type is a biotin-dependent, Na(+)-translocating enzyme that
CC       includes both soluble and membrane-bound components (cf.
CC       EC 4.1.1.89).
CC   -!- As free malonate is chemically rather inert, it has to be activated
CC       prior to decarboxylation.
CC   -!- In both enzymes, this is achieved by exchanging malonate with an
CC       acetyl group bound to an acyl-carrier protiein (ACP), to form
CC       malonyl-ACP and acetate, with subsequent decarboxylation regenerating
CC       the acetyl-ACP.
CC   -!- The ACP subunit of both enzymes differs from that found in fatty-acid
CC       biosynthesis by having phosphopantethine attached to a serine side-
CC       chain as 2'-(5-triphosphoribosyl)-3'-dephospho-CoA rather than as
CC       phosphopantetheine 4'-phosphate.
CC   -!- The individual enzymes involved in carrying out the reaction of this
CC       enzyme complex are EC 2.3.1.187, EC 2.3.1.39 and EC 4.1.1.87.
CC   -!- The carboxy group is lost with retention of configuration.
PR   PROSITE; PDOC50980;
//
ID   4.1.1.89
DE   Biotin-dependent malonate decarboxylase.
AN   Malonate carboxy-lyase (biotin-dependent).
AN   Malonate decarboxylase.
CA   Malonate + H(+) = acetate + CO(2).
CC   -!- Two types of malonate decarboxylase are currently known, both of
CC       which form multienzyme complexes.
CC   -!- The enzyme described here is a biotin-dependent, Na(+)-translocating
CC       enzyme that includes both soluble and membrane-bound components.
CC   -!- The other type is a biotin-independent cytosolic protein (cf.
CC       EC 4.1.1.88).
CC   -!- As free malonate is chemically rather inert, it has to be activated
CC       prior to decarboxylation.
CC   -!- Both enzymes achieve this by exchanging malonate with an acetyl group
CC       bound to an acyl-carrier protiein (ACP), to form malonyl-ACP and
CC       acetate, with subsequent decarboxylation regenerating the acetyl-
CC       bound form of the enzyme.
CC   -!- The ACP subunit of both enzymes differs from that found in fatty-acid
CC       biosynthesis by having phosphopantethine attached to a serine side-
CC       chain as 2'-(5-triphosphoribosyl)-3'-dephospho-CoA rather than as
CC       phosphopantetheine 4'-phosphate.
CC   -!- In the anaerobic bacterium Malonomonas rubra, the components of the
CC       multienzyme complex/enzymes involved in carrying out the reactions of
CC       this enzyme are as follows: MadA (EC 2.3.1.187), MadB (EC 4.3.99.2),
CC       MadC/MadD (EC 2.1.3.10) and MadH (EC 6.2.1.35).
CC   -!- Two other components that are involved are MadE, the acyl-carrier
CC       protein and MadF, the biotin protein.
CC   -!- The carboxy group is lost with retention of configuration.
PR   PROSITE; PDOC50980;
//
ID   4.1.1.90
DE   Peptidyl-glutamate 4-carboxylase.
AN   Gamma-glutamyl carboxylase.
AN   Vitamin K-dependent carboxylase.
CA   [Peptidyl]-4-carboxyglutamate + 2,3-epoxyphylloquinone + H(2)O =
CA   [peptidyl]-glutamate + CO(2) + O(2) + phylloquinone.
CC   -!- The enzyme can use various vitamin-K derivatives, including
CC       menaquinone, but does not contain iron.
CC   -!- In the reverse direction the mechanism appears to involve the
CC       generation of a strong base by oxygenation of vitamin K.
CC   -!- It catalyzes the post-translational modification of several proteins
CC       of the blood-clotting system.
CC   -!- 9-12 glutamate residues are converted to 4-carboxyglutamate (Gla) in
CC       a specific domain of the target protein.
DR   Q07175, VKGC_BOVIN ;  Q9MYY3, VKGC_DELLE ;  P38435, VKGC_HUMAN ;
DR   Q9QYC7, VKGC_MOUSE ;  Q5RF50, VKGC_PONAB ;  O88496, VKGC_RAT   ;
DR   Q9GL59, VKGC_SHEEP ;
//
ID   4.1.2.1
DE   Transferred entry: 4.1.3.16.
//
ID   4.1.2.2
DE   Ketotetrose-phosphate aldolase.
AN   Erythrulose-1-phosphate formaldehyde-lyase.
AN   Erythrulose-1-phosphate synthetase.
AN   Phosphoketotetrose aldolase.
CA   Erythrulose 1-phosphate = glycerone phosphate + formaldehyde.
//
ID   4.1.2.3
DE   Deleted entry.
//
ID   4.1.2.4
DE   Deoxyribose-phosphate aldolase.
AN   2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase.
AN   Deoxyriboaldolase.
AN   Phosphodeoxyriboaldolase.
CA   2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate +
CA   acetaldehyde.
DR   Q65H59, DEOC1_BACLD;  Q6F1Z6, DEOC1_MESFL;  Q8EPW8, DEOC1_OCEIH;
DR   Q6A8F1, DEOC1_PROAC;  Q2YUU4, DEOC1_STAAB;  Q5HJN0, DEOC1_STAAC;
DR   P61108, DEOC1_STAAM;  P99102, DEOC1_STAAN;  Q6GKG7, DEOC1_STAAR;
DR   Q6GCY6, DEOC1_STAAS;  Q8NYR1, DEOC1_STAAW;  Q7MP37, DEOC1_VIBVY;
DR   Q8ZGH4, DEOC1_YERPE;  Q66CP8, DEOC1_YERPS;  Q65D22, DEOC2_BACLD;
DR   Q6F0H8, DEOC2_MESFL;  Q8EMT9, DEOC2_OCEIH;  Q6A655, DEOC2_PROAC;
DR   Q2YUL6, DEOC2_STAAB;  Q5HE63, DEOC2_STAAC;  P61084, DEOC2_STAAM;
DR   P99174, DEOC2_STAAN;  Q6GET8, DEOC2_STAAR;  Q6G7H3, DEOC2_STAAS;
DR   Q8NVF5, DEOC2_STAAW;  Q7MI38, DEOC2_VIBVY;  Q8ZIQ4, DEOC2_YERPE;
DR   Q66EW0, DEOC2_YERPS;  A9NG35, DEOC_ACHLI ;  A3N123, DEOC_ACTP2 ;
DR   B3H1P7, DEOC_ACTP7 ;  B0BPV4, DEOC_ACTPJ ;  A6VQW4, DEOC_ACTSZ ;
DR   A0KPE4, DEOC_AERHH ;  Q9Y948, DEOC_AERPE ;  A4SRU4, DEOC_AERS4 ;
DR   Q8UJ09, DEOC_AGRT5 ;  B6ENG3, DEOC_ALISL ;  A8MH18, DEOC_ALKOO ;
DR   Q3MF82, DEOC_ANAVT ;  O66540, DEOC_AQUAE ;  A7ZAF1, DEOC_BACA2 ;
DR   C3P786, DEOC_BACAA ;  C3L6K8, DEOC_BACAC ;  Q81RZ3, DEOC_BACAN ;
DR   B7JJK4, DEOC_BACC0 ;  Q73A11, DEOC_BACC1 ;  B7IS80, DEOC_BACC2 ;
DR   C1EQH0, DEOC_BACC3 ;  B7HIT0, DEOC_BACC4 ;  B7HMQ9, DEOC_BACC7 ;
DR   A7GNS8, DEOC_BACCN ;  B9IXA5, DEOC_BACCQ ;  Q81EY8, DEOC_BACCR ;
DR   Q63CR9, DEOC_BACCZ ;  Q9KD67, DEOC_BACHD ;  Q6HK62, DEOC_BACHK ;
DR   A8FJ14, DEOC_BACP2 ;  Q5WHF4, DEOC_BACSK ;  P39121, DEOC_BACSU ;
DR   Q89ZF2, DEOC_BACTN ;  A9VQK2, DEOC_BACWK ;  Q6MGR8, DEOC_BDEBA ;
DR   Q3T0V9, DEOC_BOVIN ;  C0ZB54, DEOC_BREBN ;  Q1BVA7, DEOC_BURCA ;
DR   B1KCV0, DEOC_BURCC ;  A0KCV5, DEOC_BURCH ;  B4ENZ2, DEOC_BURCJ ;
DR   Q39NL8, DEOC_BURS3 ;  Q19264, DEOC_CAEEL ;  A4XLW0, DEOC_CALS8 ;
DR   Q3ABV0, DEOC_CARHZ ;  Q7NRS9, DEOC_CHRVO ;  Q97IU5, DEOC_CLOAB ;
DR   A7FU73, DEOC_CLOB1 ;  C3KVW7, DEOC_CLOB6 ;  B2V184, DEOC_CLOBA ;
DR   B2TL86, DEOC_CLOBB ;  A5I237, DEOC_CLOBH ;  C1FN33, DEOC_CLOBJ ;
DR   B1ILA1, DEOC_CLOBK ;  A7GDP8, DEOC_CLOBL ;  B1L1S5, DEOC_CLOBM ;
DR   Q18C22, DEOC_CLOD6 ;  B9E4U5, DEOC_CLOK1 ;  A5N0Z3, DEOC_CLOK5 ;
DR   A0PYX5, DEOC_CLONN ;  Q0TNQ8, DEOC_CLOP1 ;  Q8XIR2, DEOC_CLOPE ;
DR   Q0SRC4, DEOC_CLOPS ;  Q892U4, DEOC_CLOTE ;  P0CH94, DEOC_COCIM ;
DR   B5Y7V3, DEOC_COPPD ;  C3PI20, DEOC_CORA7 ;  Q6NJX0, DEOC_CORDI ;
DR   Q8FSJ0, DEOC_COREF ;  Q8NTC4, DEOC_CORGL ;  Q4JSV3, DEOC_CORJK ;
DR   B1WW41, DEOC_CYAA5 ;  B8HXS4, DEOC_CYAP4 ;  B7K8P2, DEOC_CYAP7 ;
DR   Q9RV25, DEOC_DEIRA ;  B8FUK9, DEOC_DESHD ;  Q24SU9, DEOC_DESHY ;
DR   Q6ALS3, DEOC_DESPS ;  B8E0F1, DEOC_DICTD ;  A7ZVS4, DEOC_ECO24 ;
DR   B7UR09, DEOC_ECO27 ;  B7MNI8, DEOC_ECO45 ;  B7LEM7, DEOC_ECO55 ;
DR   Q8XB36, DEOC_ECO57 ;  B5Z4R3, DEOC_ECO5E ;  B7NW61, DEOC_ECO7I ;
DR   B7N2V7, DEOC_ECO81 ;  B7LXU3, DEOC_ECO8A ;  C4ZT63, DEOC_ECOBW ;
DR   B1XFJ1, DEOC_ECODH ;  A8A8B0, DEOC_ECOHS ;  A1AJU8, DEOC_ECOK1 ;
DR   Q0T8T2, DEOC_ECOL5 ;  P0A6L1, DEOC_ECOL6 ;  B1IS38, DEOC_ECOLC ;
DR   P0A6L0, DEOC_ECOLI ;  B7NH49, DEOC_ECOLU ;  B6I6M8, DEOC_ECOSE ;
DR   B1LEI6, DEOC_ECOSM ;  C5BHJ2, DEOC_EDWI9 ;  B2KBN0, DEOC_ELUMP ;
DR   A4W698, DEOC_ENT38 ;  Q839J1, DEOC_ENTFA ;  A7MGB0, DEOC_ENTS8 ;
DR   Q6D3R0, DEOC_ERWCT ;  B2VH50, DEOC_ERWT9 ;  B7LNS1, DEOC_ESCF3 ;
DR   C4Z3P0, DEOC_EUBE2 ;  B1YKT7, DEOC_EXIS2 ;  C4L415, DEOC_EXISA ;
DR   B0S0N1, DEOC_FINM2 ;  Q0RRG0, DEOC_FRAAA ;  Q5KX02, DEOC_GEOKA ;
DR   C5D4T6, DEOC_GEOSW ;  A4IR26, DEOC_GEOTN ;  Q7NFI7, DEOC_GLOVI ;
DR   Q7VMS9, DEOC_HAEDU ;  Q4QLH8, DEOC_HAEI8 ;  A5UCY8, DEOC_HAEIE ;
DR   P44430, DEOC_HAEIN ;  B8F671, DEOC_HAEPS ;  Q0I2N7, DEOC_HAES1 ;
DR   B0UTU0, DEOC_HAES2 ;  B9LR64, DEOC_HALLT ;  Q5UX95, DEOC_HALMA ;
DR   B0R6I6, DEOC_HALS3 ;  Q9HP08, DEOC_HALSA ;  Q18FF3, DEOC_HALWD ;
DR   Q9Y315, DEOC_HUMAN ;  B5Y277, DEOC_KLEP3 ;  A6T962, DEOC_KLEP7 ;
DR   B2GG36, DEOC_KOCRD ;  Q5FLZ2, DEOC_LACAC ;  Q74IA4, DEOC_LACJO ;
DR   Q9CFM7, DEOC_LACLA ;  A2RK45, DEOC_LACLM ;  Q02YD6, DEOC_LACLS ;
DR   Q88Z64, DEOC_LACPL ;  Q38XI2, DEOC_LACSS ;  Q92A19, DEOC_LISIN ;
DR   C1KWT9, DEOC_LISMC ;  Q71Y27, DEOC_LISMF ;  B8DBT6, DEOC_LISMH ;
DR   Q8Y5R1, DEOC_LISMO ;  A0AKA1, DEOC_LISW6 ;  B1HTK8, DEOC_LYSSC ;
DR   B9E8I5, DEOC_MACCJ ;  Q65WA1, DEOC_MANSM ;  O26909, DEOC_METTH ;
DR   B0JK91, DEOC_MICAN ;  C5C9E5, DEOC_MICLC ;  Q91YP3, DEOC_MOUSE ;
DR   A0QLL2, DEOC_MYCA1 ;  B3PM95, DEOC_MYCA5 ;  P63930, DEOC_MYCBO ;
DR   A1KFV2, DEOC_MYCBP ;  C1AKF6, DEOC_MYCBT ;  Q2SRA7, DEOC_MYCCT ;
DR   Q7NAQ0, DEOC_MYCGA ;  P47296, DEOC_MYCGE ;  Q600B2, DEOC_MYCH2 ;
DR   Q4A7J6, DEOC_MYCH7 ;  Q4A9F7, DEOC_MYCHJ ;  P43048, DEOC_MYCHO ;
DR   B8ZT93, DEOC_MYCLB ;  Q9CB45, DEOC_MYCLE ;  B2HQU3, DEOC_MYCMM ;
DR   Q6KHA7, DEOC_MYCMO ;  Q6MSE7, DEOC_MYCMS ;  Q73SV2, DEOC_MYCPA ;
DR   Q8EWT4, DEOC_MYCPE ;  P47722, DEOC_MYCPI ;  P09924, DEOC_MYCPN ;
DR   Q98QP7, DEOC_MYCPU ;  Q4A5W6, DEOC_MYCS5 ;  A5TZK6, DEOC_MYCTA ;
DR   P63929, DEOC_MYCTU ;  A0PVY3, DEOC_MYCUA ;  Q3IQA5, DEOC_NATPD ;
DR   B2A4J4, DEOC_NATTJ ;  Q5YP36, DEOC_NOCFA ;  Q8YPM0, DEOC_NOSS1 ;
DR   P57937, DEOC_PASMU ;  C6DEP1, DEOC_PECCP ;  Q3A247, DEOC_PELCD ;
DR   Q7N932, DEOC_PHOLL ;  Q6LUH4, DEOC_PHOPR ;  B4EWA4, DEOC_PROMH ;
DR   Q4ZMV1, DEOC_PSEU2 ;  Q8ZXK7, DEOC_PYRAE ;  A4WHP7, DEOC_PYRAR ;
DR   A1RU26, DEOC_PYRIL ;  Q877I0, DEOC_PYRKO ;  Q92MQ3, DEOC_RHIME ;
DR   Q7UPT7, DEOC_RHOBA ;  Q2RRZ2, DEOC_RHORT ;  B5FTC5, DEOC_SALDC ;
DR   B4TGZ9, DEOC_SALHS ;  Q8Z0U3, DEOC_SALTI ;  Q8ZJV8, DEOC_SALTY ;
DR   A8G9H6, DEOC_SERP5 ;  A1S474, DEOC_SHEAM ;  B8E6P4, DEOC_SHEB2 ;
DR   A3D7J4, DEOC_SHEB5 ;  A6WRB8, DEOC_SHEB8 ;  A9KZ80, DEOC_SHEB9 ;
DR   Q086G0, DEOC_SHEFN ;  B0TQ91, DEOC_SHEHH ;  A3QGT3, DEOC_SHELP ;
DR   Q8EHK4, DEOC_SHEON ;  A8H728, DEOC_SHEPA ;  A4Y9A8, DEOC_SHEPC ;
DR   B8CKI4, DEOC_SHEPW ;  A0KU07, DEOC_SHESA ;  A8FYQ9, DEOC_SHESH ;
DR   Q0HLF0, DEOC_SHESM ;  Q0HXQ4, DEOC_SHESR ;  A1RH87, DEOC_SHESW ;
DR   B1KRP8, DEOC_SHEWM ;  B2TZR4, DEOC_SHIB3 ;  Q31SV8, DEOC_SHIBS ;
DR   Q327L5, DEOC_SHIDS ;  Q0SX30, DEOC_SHIF8 ;  Q83P02, DEOC_SHIFL ;
DR   Q3YU12, DEOC_SHISS ;  A6UCC1, DEOC_SINMW ;  B9DMC3, DEOC_STACT ;
DR   Q5HM84, DEOC_STAEQ ;  Q8CNH7, DEOC_STAES ;  Q4L819, DEOC_STAHJ ;
DR   Q49Z84, DEOC_STAS1 ;  Q3JYQ4, DEOC_STRA1 ;  Q8E2U1, DEOC_STRA3 ;
DR   Q8DWZ0, DEOC_STRA5 ;  C0M9B0, DEOC_STRE4 ;  B4U2S5, DEOC_STREM ;
DR   A8AX59, DEOC_STRGC ;  Q8DU34, DEOC_STRMU ;  Q99Y51, DEOC_STRP1 ;
DR   Q04L69, DEOC_STRP2 ;  P0DA62, DEOC_STRP3 ;  B5E3L5, DEOC_STRP4 ;
DR   Q5XA31, DEOC_STRP6 ;  C1C6H7, DEOC_STRP7 ;  P63932, DEOC_STRP8 ;
DR   Q1J9Z9, DEOC_STRPB ;  Q1JK46, DEOC_STRPC ;  Q1JF38, DEOC_STRPD ;
DR   Q1J4Z3, DEOC_STRPF ;  A2RCN4, DEOC_STRPG ;  B1IB13, DEOC_STRPI ;
DR   B8ZNP4, DEOC_STRPJ ;  Q48RH2, DEOC_STRPM ;  Q97RH2, DEOC_STRPN ;
DR   P0DA63, DEOC_STRPQ ;  B2INW0, DEOC_STRPS ;  B5XID8, DEOC_STRPZ ;
DR   Q8DQC4, DEOC_STRR6 ;  A4W1L5, DEOC_STRS2 ;  C0MG52, DEOC_STRS7 ;
DR   A3CMP6, DEOC_STRSV ;  A4VVB2, DEOC_STRSY ;  B9DS93, DEOC_STRU0 ;
DR   C1CDJ0, DEOC_STRZJ ;  C1CJT2, DEOC_STRZP ;  C1CS48, DEOC_STRZT ;
DR   Q67RZ3, DEOC_SYMTH ;  B1XI10, DEOC_SYNP2 ;  Q5N4L8, DEOC_SYNP6 ;
DR   P73618, DEOC_SYNY3 ;  Q9HKB7, DEOC_THEAC ;  Q8DJZ1, DEOC_THEEB ;
DR   C5A366, DEOC_THEGJ ;  Q9X1P5, DEOC_THEMA ;  B1YB76, DEOC_THENV ;
DR   A5IM24, DEOC_THEP1 ;  B0KA53, DEOC_THEP3 ;  B0K709, DEOC_THEPX ;
DR   B1LB68, DEOC_THESQ ;  Q72JE9, DEOC_THET2 ;  Q5SJ28, DEOC_THET8 ;
DR   Q8RB49, DEOC_THETN ;  Q97CC6, DEOC_THEVO ;  Q73QJ5, DEOC_TREDE ;
DR   O83288, DEOC_TREPA ;  B2S2L2, DEOC_TREPS ;  Q0W6M2, DEOC_UNCMA ;
DR   B1AJM6, DEOC_UREP2 ;  Q9PPQ4, DEOC_UREPA ;  B5ZCA0, DEOC_UREU1 ;
DR   A5F5S6, DEOC_VIBC3 ;  Q9KPL7, DEOC_VIBCH ;  C3LQC2, DEOC_VIBCM ;
DR   Q5E7J7, DEOC_VIBF1 ;  B5FA98, DEOC_VIBFM ;  A7MUW7, DEOC_VIBHB ;
DR   Q87M22, DEOC_VIBPA ;  B7VJF8, DEOC_VIBSL ;  Q8DBT2, DEOC_VIBVU ;
DR   A1JM38, DEOC_YERE8 ;  A7FK39, DEOC_YERP3 ;  Q1CAE0, DEOC_YERPA ;
DR   B2K9V8, DEOC_YERPB ;  A9R4U4, DEOC_YERPG ;  Q1CG96, DEOC_YERPN ;
DR   A4TN86, DEOC_YERPP ;  B1JRK6, DEOC_YERPY ;
//
ID   4.1.2.5
DE   Threonine aldolase.
AN   L-threonine acetaldehyde-lyase.
CA   L-threonine = glycine + acetaldehyde.
CF   Pyridoxal 5'-phosphate.
DR   O74267, GLY1_ASHGO ;  O13427, GLY1_CANAL ;  O13940, GLY1_SCHPO ;
DR   P37303, GLY1_YEAST ;  P58319, LTAE_ECO57 ;  P75823, LTAE_ECOLI ;
DR   Q9HTF1, LTAE_PSEAE ;  O50584, LTAE_PSEUN ;
//
ID   4.1.2.6
DE   Deleted entry.
//
ID   4.1.2.7
DE   Transferred entry: 4.1.2.13.
//
ID   4.1.2.8
DE   Indole-3-glycerol-phosphate lyase.
AN   (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-
AN   phosphate-lyase.
AN   Indole glycerol phosphate hydrolase.
AN   Indole synthase.
AN   Indole-3-glycerol phosphate lyase.
AN   Indole-3-glycerolphosphate D-glyceraldehyde-3-phosphate-lyase.
AN   Indoleglycerolphosphate aldolase.
AN   Tryptophan synthase alpha.
AN   TSA.
CA   (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = indole + D-glyceraldehyde
CA   3-phosphate.
CC   -!- Forms part of the defense mechanism against insects and microbial
CC       pathogens in the grass family, Gramineae, where it catalyzes one of
CC       the steps in the formation of the cyclic hydroxamic acids 2,4-
CC       dihydroxy-2H-1,4-benzoxazin-3(4H)-one (DIBOA) and 2,4-dihydroxy-7-
CC       methoxy-2H-1,4-benzoxazin-3(4H)-one (DIMBOA).
CC   -!- Resembles the alpha-subunit of EC 4.2.1.20 but, unlike tryptophan
CC       synthase, its activity is independent of the beta-subunit and free
CC       indole is released.
PR   PROSITE; PDOC00151;
DR   P42390, TRPA_MAIZE ;
//
ID   4.1.2.9
DE   Phosphoketolase.
AN   D-xylulose-5-phosphate D-glyceraldehyde-3-phosphate-lyase (phosphate-
AN   acetylating).
AN   Xylulose-5-phosphate phosphoketolase.
CA   D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde
CA   3-phosphate + H(2)O.
CF   Thiamine diphosphate.
DR   Q9AEM9, XFP_BIFAS  ;  Q937F6, XPKA_LACPE ;
//
ID   4.1.2.10
DE   (R)-mandelonitrile lyase.
AN   (R)-oxynitrilase.
AN   D-oxynitrilase.
AN   Hydroxynitrile lyase.
AN   Mandelonitrile benzaldehyde-lyase.
CA   (R)-mandelonitrile = cyanide + benzaldehyde.
CF   Flavoprotein.
CC   -!- A variety of enzymes from different sources and with different
CC       properties.
CC   -!- Some are flavoproteins, others are not.
CC   -!- Active toward a number of aromatic and aliphatic hydroxynitriles
CC       (cyanohydrins).
DR   O24243, MDL1_PRUDU ;  P52706, MDL1_PRUSE ;  O50048, MDL2_PRUSE ;
DR   P52707, MDL3_PRUSE ;  O82784, MDL4_PRUSE ;  Q9SSM2, MDLL_ARATH ;
//
ID   4.1.2.11
DE   Hydroxymandelonitrile lyase.
AN   (S)-4-hydroxymandelonitrile hydroxybenzaldehyde-lyase.
AN   Hydroxynitrile lyase.
CA   (S)-4-hydroxymandelonitrile = cyanide + 4-hydroxybenzaldehyde.
CC   -!- Does not accept aliphatic hydroxynitriles, unlike EC 4.1.2.10 and
CC       EC 4.1.2.37.
DR   P52708, HNLS_SORBI ;
//
ID   4.1.2.12
DE   2-dehydropantoate aldolase.
AN   2-dehydropantoate formaldehyde-lyase.
AN   Ketopantoaldolase.
CA   2-dehydropantoate = 3-methyl-2-oxobutanoate + formaldehyde.
//
ID   4.1.2.13
DE   Fructose-bisphosphate aldolase.
AN   Aldolase.
AN   D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase.
AN   Fructose-1,6-bisphosphate triosephosphate-lyase.
CA   D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde
CA   3-phosphate.
CF   Zinc.
CC   -!- Also acts on (3S,4R)-ketose 1-phosphates.
CC   -!- The enzymes increase electron-attraction by the carbonyl group, some
CC       (Class I) forming a protonated imine with it, others (Class II),
CC       mainly of microbial origin, polarizing it with a metal ion, e.g.
CC       zinc.
CC   -!- Formerly EC 4.1.2.7.
PR   PROSITE; PDOC00143;
PR   PROSITE; PDOC00523;
DR   Q4KMC8, ALDCA_DANRE;  Q8JH70, ALDCB_DANRE;  P04075, ALDOA_HUMAN;
DR   P05064, ALDOA_MOUSE;  A5A6I5, ALDOA_PANTR;  Q5NVR5, ALDOA_PONAB;
DR   P00883, ALDOA_RABIT;  P05065, ALDOA_RAT  ;  Q3T0S5, ALDOB_BOVIN;
DR   P07341, ALDOB_CHICK;  Q8JH71, ALDOB_DANRE;  P05062, ALDOB_HUMAN;
DR   Q91Y97, ALDOB_MOUSE;  Q5RFA6, ALDOB_PONAB;  P79226, ALDOB_RABIT;
DR   P00884, ALDOB_RAT  ;  P52210, ALDOB_SHEEP;  P53447, ALDOB_SPAAU;
DR   P53448, ALDOC_CARAU;  P53449, ALDOC_CHICK;  P09972, ALDOC_HUMAN;
DR   Q9GKW3, ALDOC_MACFA;  P05063, ALDOC_MOUSE;  Q5R1X4, ALDOC_PANTR;
DR   P09117, ALDOC_RAT  ;  Q9YG90, ALF1_AERPE ;  P54216, ALF1_CAEEL ;
DR   Q9PKH8, ALF1_CHLMU ;  Q9Z8Q7, ALF1_CHLPN ;  O84217, ALF1_CHLTR ;
DR   Q97TN4, ALF1_CLOAB ;  A6LXU8, ALF1_CLOB8 ;  Q59100, ALF1_CUPNH ;
DR   P0A992, ALF1_ECOL6 ;  P0A991, ALF1_ECOLI ;  Q8RGH3, ALF1_FUSNN ;
DR   P53445, ALF1_LAMJA ;  Q8ELI2, ALF1_OCEIH ;  Q96UH7, ALF1_PARBA ;
DR   P46256, ALF1_PEA   ;  B2RLG9, ALF1_PORG3 ;  P60053, ALF1_PORGI ;
DR   Q9V2I6, ALF1_PYRAB ;  P58314, ALF1_PYRFU ;  O57840, ALF1_PYRHO ;
DR   Q8J308, ALF1_PYRKO ;  P27995, ALF1_RHOSH ;  A7X6Y6, ALF1_STAA1 ;
DR   A6U4Y6, ALF1_STAA2 ;  Q2FDQ4, ALF1_STAA3 ;  Q2FV17, ALF1_STAA8 ;
DR   A5IW31, ALF1_STAA9 ;  Q2YWF3, ALF1_STAAB ;  Q5HCU6, ALF1_STAAC ;
DR   A6QK93, ALF1_STAAE ;  P67472, ALF1_STAAM ;  P99117, ALF1_STAAN ;
DR   Q6GDJ7, ALF1_STAAR ;  Q6G670, ALF1_STAAS ;  A8Z3K5, ALF1_STAAT ;
DR   Q8NUM5, ALF1_STAAW ;  Q07159, ALF1_STACT ;  Q5HL21, ALF1_STAEQ ;
DR   Q8CMY5, ALF1_STAES ;  Q4L9B6, ALF1_STAHJ ;  P74309, ALF1_SYNY3 ;
DR   P58315, ALF1_THETE ;  Q73QV3, ALF1_TREDE ;  Q8PHB5, ALF1_XANAC ;
DR   Q8P5Z7, ALF1_XANCP ;  Q9PF52, ALF1_XYLFA ;  Q87AI0, ALF1_XYLFT ;
DR   P46563, ALF2_CAEEL ;  Q59101, ALF2_CUPNH ;  P53446, ALF2_LAMJA ;
DR   Q8J0N6, ALF2_PARBA ;  P46257, ALF2_PEA   ;  P49577, ALF2_PLABA ;
DR   P50923, ALF2_RHOCA ;  P29271, ALF2_RHOSH ;  Q5HE75, ALF2_STAAC ;
DR   P67477, ALF2_STAAM ;  P99075, ALF2_STAAN ;  Q6GEV0, ALF2_STAAR ;
DR   Q6G7I5, ALF2_STAAS ;  P67478, ALF2_STAAW ;  Q5HM97, ALF2_STAEQ ;
DR   Q8CNI3, ALF2_STAES ;  Q55664, ALF2_SYNY3 ;  Q9SJU4, ALFC1_ARATH;
DR   Q01516, ALFC1_PEA  ;  Q944G9, ALFC2_ARATH;  Q01517, ALFC2_PEA  ;
DR   Q9ZU52, ALFC3_ARATH;  Q42690, ALFC_CHLRE ;  Q40677, ALFC_ORYSJ ;
DR   P84722, ALFC_PINST ;  P16096, ALFC_SPIOL ;  P83155, ALF_ANASL  ;
DR   P22197, ALF_ARATH  ;  Q9HGY9, ALF_ASPOR  ;  P13243, ALF_BACSU  ;
DR   O51401, ALF_BORBU  ;  P57526, ALF_BUCAI  ;  Q8K9B2, ALF_BUCAP  ;
DR   Q89AB6, ALF_BUCBP  ;  Q0PAS0, ALF_CAMJE  ;  A1VYV7, ALF_CAMJJ  ;
DR   Q9URB4, ALF_CANAL  ;  O65735, ALF_CICAR  ;  P0CJ44, ALF_COCIM  ;
DR   P19537, ALF_CORGL  ;  Q86A67, ALF_DICDI  ;  P07764, ALF_DROME  ;
DR   Q9GP32, ALF_ECHMU  ;  P0AB72, ALF_ECO57  ;  P0AB71, ALF_ECOLI  ;
DR   O52402, ALF_EDWI9  ;  Q8SSM8, ALF_ENCCU  ;  P94453, ALF_GEOSE  ;
DR   P44429, ALF_HAEIN  ;  Q9ZMQ6, ALF_HELPJ  ;  P56109, ALF_HELPY  ;
DR   Q9C2U0, ALF_KLULA  ;  P91759, ALF_LYMST  ;  P08440, ALF_MAIZE  ;
DR   P67476, ALF_MYCBO  ;  P47269, ALF_MYCGE  ;  O69600, ALF_MYCLE  ;
DR   P75089, ALF_MYCPN  ;  P67475, ALF_MYCTU  ;  P53444, ALF_NEUCR  ;
DR   Q9XDP3, ALF_NOSCO  ;  Q8YNK2, ALF_NOSS1  ;  P17784, ALF_ORYSJ  ;
DR   Q7KQL9, ALF_PLAF7  ;  P14223, ALF_PLAFA  ;  Q9I5Y1, ALF_PSEAE  ;
DR   O87796, ALF_PSEST  ;  P58336, ALF_RHIME  ;  P53442, ALF_SCHMA  ;
DR   P36580, ALF_SCHPO  ;  P0AB73, ALF_SHIFL  ;  P56888, ALF_SINMW  ;
DR   P29356, ALF_SPIOL  ;  Q9X8R6, ALF_STRCO  ;  Q9ZEM7, ALF_STRGB  ;
DR   P68905, ALF_STRP1  ;  P0CZ58, ALF_STRP3  ;  Q5XA12, ALF_STRP6  ;
DR   P68906, ALF_STRP8  ;  P0A4S1, ALF_STRPN  ;  P0CZ59, ALF_STRPQ  ;
DR   P0A4S2, ALF_STRR6  ;  Q703I2, ALF_THECA  ;  O83668, ALF_TREPA  ;
DR   P07752, ALF_TRYBB  ;  Q9PPP3, ALF_UREPA  ;  Q56815, ALF_XANFL  ;
DR   P14540, ALF_YEAST  ;
//
ID   4.1.2.14
DE   2-dehydro-3-deoxy-phosphogluconate aldolase.
AN   2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate-
AN   lyase.
AN   2-keto-3-deoxy-6-phosphogluconate aldolase.
AN   KDPG-aldolase.
AN   Phospho-2-dehydro-3-deoxygluconate aldolase.
AN   Phospho-2-keto-3-deoxygluconate aldolase.
CA   2-dehydro-3-deoxy-D-gluconate 6-phosphate = pyruvate + D-glyceraldehyde
CA   3-phosphate.
CC   -!- Also acts on 2-oxobutanoate.
PR   PROSITE; PDOC00144;
DR   O68283, ALKD_PSEAE ;  P00885, ALKD_PSEPU ;  P50846, ALKH_BACSU ;
DR   P38448, ALKH_DICD3 ;  P0A957, ALKH_ECO57 ;  P0A956, ALKH_ECOL6 ;
DR   P0A955, ALKH_ECOLI ;  P44480, ALKH_HAEIN ;  P0A958, ALKH_SHIFL ;
DR   O83578, ALKH_TREPA ;  Q00384, ALKH_ZYMMO ;
//
ID   4.1.2.15
DE   Transferred entry: 2.5.1.54.
//
ID   4.1.2.16
DE   Transferred entry: 2.5.1.55.
//
ID   4.1.2.17
DE   L-fuculose-phosphate aldolase.
AN   Fuculose aldolase.
AN   L-fuculose 1-phosphate aldolase.
AN   L-fuculose-1-phosphate lactaldehyde-lyase.
CA   L-fuculose 1-phosphate = glycerone phosphate + (S)-lactaldehyde.
DR   Q8X6R8, FUCA_ECO57 ;  Q8FEF0, FUCA_ECOL6 ;  P0AB87, FUCA_ECOLI ;
DR   P44777, FUCA_HAEIN ;  A6UTG8, FUCA_META3 ;  Q58813, FUCA_METJA ;
DR   A4FWY9, FUCA_METM5 ;  A6VGC7, FUCA_METM7 ;  Q6LY06, FUCA_METMP ;
DR   A6UPI8, FUCA_METVS ;  P0AB88, FUCA_SHIFL ;
//
ID   4.1.2.18
DE   2-dehydro-3-deoxy-L-pentonate aldolase.
AN   2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase.
AN   2-keto-3-deoxy-L-arabonate aldolase.
AN   2-keto-3-deoxy-L-pentonate aldolase.
CA   2-dehydro-3-deoxy-L-pentonate = pyruvate + glycolaldehyde.
//
ID   4.1.2.19
DE   Rhamnulose-1-phosphate aldolase.
AN   L-rhamnulose 1-phosphate aldolase.
AN   L-rhamnulose-1-phosphate lactaldehyde-lyase.
AN   L-rhamnulose-phosphate aldolase.
CA   L-rhamnulose 1-phosphate = glycerone phosphate + (S)-lactaldehyde.
DR   Q8A1A0, RHAD_BACTN ;  A8AL31, RHAD_CITK8 ;  A7ZUB3, RHAD_ECO24 ;
DR   B7UNM3, RHAD_ECO27 ;  B7MI34, RHAD_ECO45 ;  B7L9F8, RHAD_ECO55 ;
DR   Q8X8A1, RHAD_ECO57 ;  B5YZ39, RHAD_ECO5E ;  B7NUA6, RHAD_ECO7I ;
DR   B7N2P3, RHAD_ECO81 ;  B7M6V4, RHAD_ECO8A ;  C5A070, RHAD_ECOBW ;
DR   B1XB69, RHAD_ECODH ;  A8A705, RHAD_ECOHS ;  A1AI79, RHAD_ECOK1 ;
DR   Q0TAG1, RHAD_ECOL5 ;  Q8FBE1, RHAD_ECOL6 ;  B1IVH6, RHAD_ECOLC ;
DR   P32169, RHAD_ECOLI ;  B7NFK0, RHAD_ECOLU ;  B6I4P4, RHAD_ECOSE ;
DR   B1LMU2, RHAD_ECOSM ;  A4WG94, RHAD_ENT38 ;  Q838L1, RHAD_ENTFA ;
DR   A7ML62, RHAD_ENTS8 ;  Q6DA25, RHAD_ERWCT ;  B7LVE1, RHAD_ESCF3 ;
DR   B5XZ54, RHAD_KLEP3 ;  A6TGA6, RHAD_KLEP7 ;  Q88S52, RHAD_LACPL ;
DR   Q926R2, RHAD_LISIN ;  C1L0I0, RHAD_LISMC ;  Q71VR5, RHAD_LISMF ;
DR   B8DCW3, RHAD_LISMH ;  Q8Y3I8, RHAD_LISMO ;  A0AFI3, RHAD_LISW6 ;
DR   Q65Q26, RHAD_MANSM ;  Q8ESW9, RHAD_OCEIH ;  C6DJR1, RHAD_PECCP ;
DR   B5F0M6, RHAD_SALA4 ;  Q57HH1, RHAD_SALCH ;  B5FP38, RHAD_SALDC ;
DR   B5QWY1, RHAD_SALEP ;  B5RFC6, RHAD_SALG2 ;  B4TBY0, RHAD_SALHS ;
DR   B4SZZ0, RHAD_SALNS ;  Q5PKG5, RHAD_SALPA ;  A9MZC4, RHAD_SALPB ;
DR   C0Q3L1, RHAD_SALPC ;  B5BJG5, RHAD_SALPK ;  B4TPQ6, RHAD_SALSV ;
DR   P69737, RHAD_SALTI ;  Q8ZKS1, RHAD_SALTY ;  Q31U87, RHAD_SHIBS ;
DR   Q32A68, RHAD_SHIDS ;  Q83PE1, RHAD_SHIFL ;  Q3YV74, RHAD_SHISS ;
DR   A7FN83, RHAD_YERP3 ;  Q1C0V7, RHAD_YERPA ;  B2K1W0, RHAD_YERPB ;
DR   Q8ZJ03, RHAD_YERPE ;  A9QYS3, RHAD_YERPG ;  Q1CEB1, RHAD_YERPN ;
DR   A4TRT2, RHAD_YERPP ;  Q66FF5, RHAD_YERPS ;  B1JND0, RHAD_YERPY ;
//
ID   4.1.2.20
DE   2-dehydro-3-deoxyglucarate aldolase.
AN   2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase.
AN   2-keto-3-deoxyglucarate aldolase.
AN   Alpha-keto-beta-deoxy-D-glucarate aldolase.
CA   2-dehydro-3-deoxy-D-glucarate = pyruvate + tartronate semialdehyde.
DR   A8AQ14, GARL_CITK8 ;  A7ZS18, GARL_ECO24 ;  B7UJ26, GARL_ECO27 ;
DR   B7MB51, GARL_ECO45 ;  B7LH62, GARL_ECO55 ;  Q8XAE3, GARL_ECO57 ;
DR   B5YS14, GARL_ECO5E ;  B7NJZ1, GARL_ECO7I ;  B7M032, GARL_ECO8A ;
DR   C4ZR38, GARL_ECOBW ;  B1XGT9, GARL_ECODH ;  A8A4T9, GARL_ECOHS ;
DR   A1AG35, GARL_ECOK1 ;  Q0TCY1, GARL_ECOL5 ;  Q8FDB8, GARL_ECOL6 ;
DR   B1IRJ2, GARL_ECOLC ;  P23522, GARL_ECOLI ;  B7NDB2, GARL_ECOLU ;
DR   B6I1J9, GARL_ECOSE ;  B1LFM7, GARL_ECOSM ;  Q1R6L1, GARL_ECOUT ;
DR   A4WEU6, GARL_ENT38 ;  B7LMV6, GARL_ESCF3 ;  A6TEE9, GARL_KLEP7 ;
DR   B5F6Q5, GARL_SALA4 ;  A9MPQ4, GARL_SALAR ;  Q57JL0, GARL_SALCH ;
DR   B5FHY2, GARL_SALDC ;  B5QZS6, GARL_SALEP ;  B5REK4, GARL_SALG2 ;
DR   B4TIX5, GARL_SALHS ;  B4T6B6, GARL_SALNS ;  Q5PCB8, GARL_SALPA ;
DR   A9N6Z0, GARL_SALPB ;  C0PZ22, GARL_SALPC ;  B4TVY2, GARL_SALSV ;
DR   Q8XGF9, GARL_SALTI ;  Q7CPQ8, GARL_SALTY ;  B2U092, GARL_SHIB3 ;
DR   Q31WQ5, GARL_SHIBS ;  Q32BJ0, GARL_SHIDS ;  Q3YXA5, GARL_SHISS ;
//
ID   4.1.2.21
DE   2-dehydro-3-deoxy-6-phosphogalactonate aldolase.
AN   2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-
AN   lyase.
AN   2-dehydro-3-deoxyphosphogalactonate aldolase.
AN   2-oxo-3-deoxygalactonate 6-phosphate aldolase.
AN   6-phospho-2-dehydro-3-deoxygalactonate aldolase.
AN   6-phospho-2-keto-3-deoxygalactonate aldolase.
CA   2-dehydro-3-deoxy-D-galactonate 6-phosphate = pyruvate + D-glyceraldehyde
CA   3-phosphate.
DR   Q6BF16, DGOA_ECOLI ;
//
ID   4.1.2.22
DE   Fructose-6-phosphate phosphoketolase.
AN   D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (phosphate-
AN   acetylating).
CA   D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose
CA   4-phosphate + H(2)O.
CF   Thiamine diphosphate.
CC   -!- Also acts on D-xylulose 5-phosphate.
DR   Q9AEM9, XFP_BIFAS  ;
//
ID   4.1.2.23
DE   3-deoxy-D-manno-octulosonate aldolase.
AN   3-deoxy-D-manno-octulosonate D-arabinose-lyase.
CA   3-deoxy-D-manno-octulosonate = pyruvate + D-arabinose.
//
ID   4.1.2.24
DE   Dimethylaniline-N-oxide aldolase.
AN   N,N-dimethylaniline-N-oxide formaldehyde-lyase.
CA   N,N-dimethylaniline N-oxide = N-methylaniline + formaldehyde.
CC   -!- Acts on various N,N-dialkylarylamides.
//
ID   4.1.2.25
DE   Dihydroneopterin aldolase.
AN   2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-
AN   dihydropteridine glycolaldehyde-lyase.
CA   2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-
CA   dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine
CA   + glycolaldehyde.
DR   Q54YD9, FOL1_DICDI ;  P29251, FOL1_PNECA ;  Q4LB35, FOL1_SCHPO ;
DR   P53848, FOL1_YEAST ;  Q9SF23, FOLB1_ARATH;  P28823, FOLB_BACSU ;
DR   Q9PJC6, FOLB_CHLMU ;  Q9Z7E9, FOLB_CHLPN ;  O84620, FOLB_CHLTR ;
DR   P0AC17, FOLB_ECOL6 ;  P0AC16, FOLB_ECOLI ;  P46362, FOLB_HAEIN ;
DR   P71513, FOLB_METEA ;  P0A581, FOLB_MYCBO ;  O69529, FOLB_MYCLE ;
DR   P0A580, FOLB_MYCTU ;  P0AC18, FOLB_SHIFL ;  Q5HIG0, FOLB_STAAC ;
DR   P64145, FOLB_STAAM ;  P64146, FOLB_STAAN ;  Q6GJF6, FOLB_STAAR ;
DR   Q6GBX3, FOLB_STAAS ;  P56740, FOLB_STAAU ;  P64147, FOLB_STAAW ;
DR   Q5HRN9, FOLB_STAEQ ;  Q8CMT8, FOLB_STAES ;  Q59920, FOLB_STAHA ;
DR   Q9X8I0, FOLB_STRCO ;  P0C0G5, FOLB_STRP1 ;  P0DB12, FOLB_STRP3 ;
DR   Q5XCA7, FOLB_STRP6 ;  P0A3E2, FOLB_STRP8 ;  P0DB13, FOLB_STRPQ ;
DR   P0C0G4, FOLB_STRPY ;  P74342, FOLB_SYNY3 ;  P22291, SULD_STRPN ;
DR   P59657, SULD_STRR6 ;
//
ID   4.1.2.26
DE   Phenylserine aldolase.
AN   L-threo-3-phenylserine benzaldehyde-lyase.
CA   L-threo-3-phenylserine = glycine + benzaldehyde.
CF   Pyridoxal 5'-phosphate.
//
ID   4.1.2.27
DE   Sphinganine-1-phosphate aldolase.
AN   Sphinganine-1-phosphate palmitaldehyde-lyase.
AN   Sphingosine-1-phosphate aldolase.
AN   Sphingosine-1-phosphate lyase.
CA   Sphinganine 1-phosphate = phosphoethanolamine + palmitaldehyde.
CF   Pyridoxal 5'-phosphate.
DR   O95470, SGPL1_HUMAN;  Q8R0X7, SGPL1_MOUSE;  Q5R4G0, SGPL1_PONAB;
DR   Q8CHN6, SGPL1_RAT  ;  Q9C509, SGPL_ARATH ;  Q9Y194, SGPL_CAEEL ;
DR   Q54RV9, SGPL_DICDI ;  Q9V7Y2, SGPL_DROME ;  Q5X3A8, SGPL_LEGPA ;
DR   Q5ZTI6, SGPL_LEGPH ;  Q5WUR6, SGPL_LEGPL ;  Q52RG7, SGPL_ORYSJ ;
DR   Q05567, SGPL_YEAST ;
//
ID   4.1.2.28
DE   2-dehydro-3-deoxy-D-pentonate aldolase.
AN   2-keto-3-deoxy-D-pentonate aldolase.
CA   2-dehydro-3-deoxy-D-pentonate = pyruvate + glycolaldehyde.
//
ID   4.1.2.29
DE   5-dehydro-2-deoxyphosphogluconate aldolase.
AN   5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase.
AN   Phospho-5-dehydro-2-deoxygluconate aldolase.
AN   Phospho-5-keto-2-deoxygluconate aldolase.
CA   5-dehydro-2-deoxy-D-gluconate 6-phosphate = glycerone phosphate +
CA   malonate semialdehyde.
DR   A7ZAH2, IOLJ_BACA2 ;  Q9KAH3, IOLJ_BACHD ;  Q65D09, IOLJ_BACLD ;
DR   Q5WKY5, IOLJ_BACSK ;  P42420, IOLJ_BACSU ;
//
ID   4.1.2.30
DE   17-alpha-hydroxyprogesterone aldolase.
AN   17-alpha-hydroxyprogesterone acetaldehyde-lyase.
CA   17-alpha-hydroxyprogesterone = androst-4-ene-3,17-dione + acetaldehyde.
//
ID   4.1.2.31
DE   Transferred entry: 4.1.3.16.
//
ID   4.1.2.32
DE   Trimethylamine-oxide aldolase.
AN   Trimethylamine-N-oxide formaldehyde-lyase.
CA   Trimethylamine N-oxide = dimethylamine + formaldehyde.
//
ID   4.1.2.33
DE   Fucosterol-epoxide lyase.
AN   (24R,24'R)-fucosterol-epoxide acetaldehyde-lyase.
CA   (24R,24'R)-fucosterol epoxide = desmosterol + acetaldehyde.
CC   -!- The insect enzyme is involved in the conversion of sitosterol into
CC       cholesterol.
//
ID   4.1.2.34
DE   4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase.
AN   (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase.
AN   (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-formylbenzoate-lyase.
AN   2'-carboxybenzalpyruvate aldolase.
CA   (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate + H(2)O = 2-formylbenzoate +
CA   pyruvate.
CC   -!- Involved, with EC 1.13.11.38, in the metabolism of phenanthrene in
CC       bacteria.
DR   Q79EM8, PHDJ_NOCSK ;
//
ID   4.1.2.35
DE   Propioin synthase.
AN   4-hydroxy-3-hexanone aldolase.
AN   4-hydroxy-3-hexanone propanal-lyase.
CA   4-hydroxy-3-hexanone = 2 propanal.
//
ID   4.1.2.36
DE   Lactate aldolase.
AN   (S)-lactate acetaldehyde-lyase.
AN   Lactate synthase.
CA   (S)-lactate = formate + acetaldehyde.
//
ID   4.1.2.37
DE   Transferred entry: 4.1.2.46 and 4.1.2.47.
//
ID   4.1.2.38
DE   Benzoin aldolase.
AN   2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase.
AN   Benzaldehyde lyase.
CA   Benzoin = 2 benzaldehyde.
CF   Thiamine diphosphate.
DR   P51853, BZNB_PSEFL ;
//
ID   4.1.2.39
DE   Transferred entry: 4.1.2.46 and 4.1.2.47.
//
ID   4.1.2.40
DE   Tagatose-bisphosphate aldolase.
AN   D-tagatose-1,6-bisphosphate aldolase.
AN   D-tagatose-1,6-bisphosphate triosephosphate lyase.
AN   Tagatose 1,6-diphosphate aldolase.
CA   D-tagatose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde
CA   3-phosphate.
CC   -!- Enzyme activity is stimulated by certain divalent cations.
CC   -!- Involved in the tagatose 6-phosphate pathway of lactose catabolism in
CC       bacteria.
DR   A7ZNR5, GATY_ECO24 ;  B7UFB3, GATY_ECO27 ;  B7MEF1, GATY_ECO45 ;
DR   B7L9W7, GATY_ECO55 ;  Q8X4R2, GATY_ECO57 ;  B5YV43, GATY_ECO5E ;
DR   B7NPN7, GATY_ECO7I ;  B7M477, GATY_ECO8A ;  C4ZSI0, GATY_ECOBW ;
DR   B1X7I7, GATY_ECODH ;  A8A1W1, GATY_ECOHS ;  A1ACW2, GATY_ECOK1 ;
DR   Q0TFZ6, GATY_ECOL5 ;  Q8FFY7, GATY_ECOL6 ;  B1IYY4, GATY_ECOLC ;
DR   P0C8J6, GATY_ECOLI ;  B7NCC6, GATY_ECOLU ;  P0C8J7, GATY_ECOLX ;
DR   B1LN92, GATY_ECOSM ;  Q1R9X7, GATY_ECOUT ;  Q8VS16, GATY_KLEOX ;
DR   A6TEF4, GATY_KLEP7 ;  Q57JK9, GATY_SALCH ;  B5QZS8, GATY_SALEP ;
DR   B5REK6, GATY_SALG2 ;  B4TIX9, GATY_SALHS ;  B4T6B9, GATY_SALNS ;
DR   Q5PL86, GATY_SALPA ;  A9N6Z8, GATY_SALPB ;  C0PZ24, GATY_SALPC ;
DR   B5BGG5, GATY_SALPK ;  B4TWB0, GATY_SALSV ;  Q8XGZ9, GATY_SALTI ;
DR   Q7CPQ7, GATY_SALTY ;  B2TY92, GATY_SHIB3 ;  Q323C6, GATY_SHIBS ;
DR   Q32EA9, GATY_SHIDS ;  Q0T342, GATY_SHIF8 ;  Q83QY5, GATY_SHIFL ;
DR   Q3Z0B4, GATY_SHISS ;  A8AQ28, KBAY_CITK8 ;  A7ZS33, KBAY_ECO24 ;
DR   B7UJ37, KBAY_ECO27 ;  B7MB62, KBAY_ECO45 ;  B7LH72, KBAY_ECO55 ;
DR   P0AB76, KBAY_ECO57 ;  B5YS30, KBAY_ECO5E ;  B7NKL0, KBAY_ECO7I ;
DR   B7N0S6, KBAY_ECO81 ;  B7M045, KBAY_ECO8A ;  C4ZR47, KBAY_ECOBW ;
DR   B1XGU9, KBAY_ECODH ;  A8A4V3, KBAY_ECOHS ;  A1AG46, KBAY_ECOK1 ;
DR   Q0TCW8, KBAY_ECOL5 ;  P0AB75, KBAY_ECOL6 ;  B1IRH9, KBAY_ECOLC ;
DR   P0AB74, KBAY_ECOLI ;  B7NDC5, KBAY_ECOLU ;  Q9KIP8, KBAY_ECOLX ;
DR   B6I1L2, KBAY_ECOSE ;  B1LFP2, KBAY_ECOSM ;  Q1R6K0, KBAY_ECOUT ;
DR   A4WEV6, KBAY_ENT38 ;  B7LMU4, KBAY_ESCF3 ;  A9MPP7, KBAY_SALAR ;
DR   Q837X9, LACD1_ENTFA;  Q8E347, LACD1_STRA3;  P26425, LACD1_STRMU;
DR   P63703, LACD1_STRP1;  P0DC14, LACD1_STRP3;  Q5XAI4, LACD1_STRP6;
DR   P63704, LACD1_STRP8;  P0DC15, LACD1_STRPQ;  Q833W8, LACD2_ENTFA;
DR   Q8E4R8, LACD2_STRA3;  Q8DWE5, LACD2_STRMU;  P63705, LACD2_STRP1;
DR   P0DC16, LACD2_STRP3;  Q5X9Y4, LACD2_STRP6;  P63706, LACD2_STRP8;
DR   P0DC17, LACD2_STRPQ;  P26593, LACD_LACLA ;  Q92EB7, LACD_LISIN ;
DR   C1L056, LACD_LISMC ;  Q723B1, LACD_LISMF ;  B8DA86, LACD_LISMH ;
DR   Q8Y9I9, LACD_LISMO ;  A7X574, LACD_STAA1 ;  A6U3S2, LACD_STAA2 ;
DR   Q2FEU0, LACD_STAA3 ;  P0A011, LACD_STAA8 ;  A5IUY1, LACD_STAA9 ;
DR   Q2YYJ6, LACD_STAAB ;  Q5HE13, LACD_STAAC ;  A6QJ36, LACD_STAAE ;
DR   P0A009, LACD_STAAM ;  P0A010, LACD_STAAN ;  Q6GEN7, LACD_STAAR ;
DR   Q6G7C2, LACD_STAAS ;  A8YYF9, LACD_STAAT ;  Q8NVC9, LACD_STAAW ;
DR   Q5HM38, LACD_STAEQ ;  Q8CNF5, LACD_STAES ;  Q4L871, LACD_STAHJ ;
DR   Q8DXC3, LACD_STRA5 ;  Q97QL3, LACD_STRPN ;  Q8DPP2, LACD_STRR6 ;
//
ID   4.1.2.41
DE   Vanillin synthase.
CA   3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA = vanillin + acetyl-
CA   CoA.
CC   -!- Involved, together with EC 4.2.1.101 in the production of vanillin
CC       from trans-ferulic acid.
CC   -!- Vanillin is converted to vanillate by EC 1.2.1.67.
//
ID   4.1.2.42
DE   D-threonine aldolase.
AN   DTA.
AN   Low specificity D-threonine aldolase.
CA   (1) D-threonine = glycine + acetaldehyde.
CA   (2) D-allothreonine = glycine + acetaldehyde.
CF   Pyridoxal 5'-phosphate.
CC   -!- Activated by divalent metal cations (e.g. Co(2+), Ni(2+), Mn(2+) or
CC       Mg(2+)).
CC   -!- The reaction is reversible, which can lead to the interconversion of
CC       D-threonine and D-allothreonine.
CC   -!- Several other D-beta-hydroxy-alpha-amino acids, such as D-beta-
CC       phenylserine, D-beta-hydroxy-alpha-aminovaleric acid and D-beta-3,4-
CC       dihydroxyphenylserine, can also act as substrate.
DR   O82872, DTA_ARTSP  ;
//
ID   4.1.2.43
DE   3-hexulose-6-phosphate synthase.
AN   3-hexulose phosphate synthase.
AN   3-hexulosephosphate synthase.
AN   D-arabino-3-hexulose 6-phosphate formaldehyde-lyase.
AN   HPS.
CA   D-arabino-hex-3-ulose 6-phosphate = D-ribulose 5-phosphate +
CA   formaldehyde.
CF   Manganese or magnesium.
CC   -!- Specific for formaldehyde and D-ribulose 5-phosphate as substrates.
CC   -!- Ribose 5-phosphate, xylulose 5-phosphate, allulose 6-phosphate and
CC       fructose 6-phosphate cannot act as substrate.
CC   -!- This enzyme, along with EC 5.3.1.27, plays a key role in the
CC       ribulose-monophosphate cycle of formaldehyde fixation, which is
CC       present in many microorganisms that are capable of utilizing
CC       C1-compounds.
CC   -!- The hyperthermophilic and anaerobic archaeon Pyrococcus horikoshii
CC       OT3 constitutively produces a bifunctional enzyme that sequentially
CC       catalyzes the reactions of this enzyme and EC 5.3.1.27.
DR   O28964, FAEHP_ARCFU;  Q8THA9, FAEHP_METAC;  A7I6C9, FAEHP_METB6;
DR   Q46DY5, FAEHP_METBF;  Q12UK3, FAEHP_METBU;  Q2FQ74, FAEHP_METHJ;
DR   Q58842, FAEHP_METJA;  Q8PXE1, FAEHP_METMA;  A3CUG8, FAEHP_METMJ;
DR   B8GGX9, FAEHP_METPE;  Q2NE86, FAEHP_METST;  O27518, FAEHP_METTH;
DR   A0B7U9, FAEHP_METTP;  Q0W644, FAEHP_UNCMA;  Q49WT7, HPS1_STAS1 ;
DR   Q49WT0, HPS2_STAS1 ;  Q49VB7, HPS3_STAS1 ;  P42405, HPS_BACSU  ;
DR   Q48907, HPS_METAM  ;  Q46DA4, HPS_METBF  ;  Q9LBW4, HPS_MYCGS  ;
DR   Q2FJ70, HPS_STAA3  ;  Q2G0K7, HPS_STAA8  ;  Q2YS94, HPS_STAAB  ;
DR   Q5HIA5, HPS_STAAC  ;  Q99W39, HPS_STAAM  ;  Q7A774, HPS_STAAN  ;
DR   Q6GJ99, HPS_STAAR  ;  Q6GBR7, HPS_STAAS  ;  Q8NXX1, HPS_STAAW  ;
DR   Q5HRH7, HPS_STAEQ  ;  Q8CQ69, HPS_STAES  ;  Q4L3P8, HPS_STAHJ  ;
//
ID   4.1.2.44
DE   Benzoyl-CoA-dihydrodiol lyase.
AN   Dihydrodiol transforming enzyme.
CA   2,3-dihydro-2,3-dihydroxybenzoyl-CoA + H(2)O = 3,4-dehydroadipyl-CoA
CA   semialdehyde + formate.
CC   -!- The enzyme is involved in the aerobic benzoyl-CoA catabolic pathway
CC       in Azoarcus evansii.
CC   -!- In a previous step benzoyl-CoA is oxidized to 2,3-dihydro-2,3-
CC       dihydroxybenzoyl-CoA (benzoyl-CoA dihydrodiol) by EC 1.14.12.21 in
CC       the presence of molecular oxygen.
CC   -!- Formerly EC 4.1.2.n1.
DR   Q84HH6, BOXC_AZOEV ;
//
ID   4.1.2.45
DE   Trans-o-hydroxybenzylidenepyruvate hydratase-aldolase.
AN   2'-hydroxybenzalpyruvate aldolase.
CA   (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H(2)O = salicylaldehyde +
CA   pyruvate.
CC   -!- This enzyme is involved in naphthalene degradation.
CC   -!- The enzyme catalyzes a retro-aldol reaction in vitro, and it accepts
CC       a broad range of aldehydes and 4-substituted 2-oxobut-3-enoates as
CC       substrates.
//
ID   4.1.2.46
DE   Aliphatic (R)-hydroxynitrile lyase.
AN   (R)-hydroxynitrile lyase.
AN   (R)-oxynitrilase.
CA   (2R)-2-hydroxy-2-methylbutanenitrile = cyanide + butan-2-one.
CF   Zinc.
CC   -!- The enzyme catalyzes the stereoselective synthesis of aliphatic (R)-
CC       cyanohydrins.
CC   -!- No activity toward mandelonitrile and 4-hydroxymandelonitrile.
CC   -!- Natural substrates for the (R)-oxynitrilase from Linum usitatissimum
CC       are acetone and butan-2-one, which are the building blocks of the
CC       cyanogen glycosides in Linum, linamarin and lotaustralin,
CC       or linustatin and neolinustatin, respectively.
CC   -!- Formerly EC 4.1.2.37 and EC 4.1.2.39.
//
ID   4.1.2.47
DE   (S)-hydroxynitrile lyase.
AN   (S)-cyanohydrin producing hydroxynitrile lyase.
AN   (S)-oxynitrilase.
AN   Hydroxynitrile lyase.
AN   Oxynitrilase.
CA   (1) An aliphatic (S)-hydroxynitrile = cyanide + an aliphatic aldehyde or
CA   ketone.
CA   (2) An aromatic (S)-hydroxynitrile = cyanide + an aromatic aldehyde.
CC   -!- Hydroxynitrile lyases catalyzes the the cleavage of hydroxynitriles
CC       into cyanide and the corresponding aldehyde or ketone.
CC   -!- In nature the liberation of cyanide serves as a defense mechanism
CC       against herbivores and microbial attack in plants.
CC   -!- In vitro the enzymes from Manihot esculenta and Hevea brasiliensis
CC       accept a broad range of aliphatic and aromatic carbonyl compounds as
CC       substrates and catalyze the formation of (S)-hydroxynitriles.
CC   -!- Formerly EC 4.1.2.37 and EC 4.1.2.39.
DR   P52704, HNL_HEVBR  ;  P52705, HNL_MANES  ;
//
ID   4.1.2.n1
DE   Transferred entry: 4.1.2.44.
//
ID   4.1.2.n2
DE   2-hydroxyphytanoyl-CoA lyase.
AN   2-HPCL.
CA   2-hydroxyphytanoyl-CoA = formyl-CoA + pristanal.
CF   Thiamine diphosphate and magnesium.
CC   -!- The enzyme can also use other 3-methyl-branched fatty acids as
CC       substrates.
//
ID   4.1.2.n3
DE   2-keto-3-deoxy-L-rhamnonate aldolase.
AN   2-dehydro-3-deoxyrhamnonate aldolase.
AN   2-keto-3-deoxy acid sugar aldolase.
AN   KDR aldolase.
CA   2-dehydro-3-deoxy-L-rhamnonate = pyruvate + (R)-lactaldehyde.
CF   Magnesium.
CC   -!- The enzyme catalyzes the reversible retro-aldol cleavage of 2-keto-3-
CC       deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde.
CC   -!- 2-keto-3-deoxy-L-mannonate, 2-keto-3-deoxy-L-lyxonate and 4-hydroxy-
CC       2-ketoheptane-1,7-dioate (HKHD) are also reasonably good substrates,
CC       although 2-keto-3-deoxy-L-rhamnonate is likely to be the
CC       physiological substrate.
DR   B7MG11, RHMA_ECO45 ;  Q8XE09, RHMA_ECO57 ;  B7NN63, RHMA_ECO7I ;
DR   B7MXS6, RHMA_ECO81 ;  C4ZU87, RHMA_ECOBW ;  B1X8V8, RHMA_ECODH ;
DR   A8A2B1, RHMA_ECOHS ;  A1AD97, RHMA_ECOK1 ;  Q0TFJ7, RHMA_ECOL5 ;
DR   Q8FFN0, RHMA_ECOL6 ;  B1IXU2, RHMA_ECOLC ;  P76469, RHMA_ECOLI ;
DR   B7N5L0, RHMA_ECOLU ;  B1LLJ9, RHMA_ECOSM ;  Q1R9H0, RHMA_ECOUT ;
DR   A6TBU6, RHMA_KLEP7 ;  B5EZG8, RHMA_SALA4 ;  Q57M64, RHMA_SALCH ;
DR   B5FNS9, RHMA_SALDC ;  B5R262, RHMA_SALEP ;  B5RCB4, RHMA_SALG2 ;
DR   B4TBF6, RHMA_SALHS ;  B4SYW1, RHMA_SALNS ;  Q5PI50, RHMA_SALPA ;
DR   A9N5C4, RHMA_SALPB ;  C0Q079, RHMA_SALPC ;  B5BCQ6, RHMA_SALPK ;
DR   B4TPH2, RHMA_SALSV ;  Q8Z549, RHMA_SALTI ;  Q8ZNG0, RHMA_SALTY ;
DR   Q31Z78, RHMA_SHIBS ;  Q32DU2, RHMA_SHIDS ;  Q3YZW1, RHMA_SHISS ;
//
ID   4.1.2.n4
DE   4-hydroxy-2-oxo-heptane-1,7-dioate aldolase.
AN   2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase.
AN   4-hydroxy-2-ketoheptane-1,7-dioate aldolase.
AN   HHED aldolase.
AN   HKHD aldolase.
CA   4-hydroxy-2-ketoheptane-1,7-dioate = pyruvate + succinate semialdehyde.
CF   Manganese or cobalt.
CC   -!- Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2-
CC       ketoheptane-1,7-dioate (HKHD) to pyruvate and succinic semialdehyde.
CC   -!- Is also able to catalyze the aldol cleavage of 4-hydroxy-2-
CC       ketopentanoate and 4-hydroxy-2-ketohexanoate, and exhibits
CC       significant oxaloacetate decarboxylase activity in vitro.
CC   -!- In the reverse direction, is able to condense a range of aldehyde
CC       acceptors with pyruvate.
DR   A8A876, HPCH_ECOHS ;  B1IS70, HPCH_ECOLC ;  Q47098, HPCH_ECOLX ;
DR   B6I2N1, HPCH_ECOSE ;  B5Y2D2, HPCH_KLEP3 ;  A6THU5, HPCH_KLEP7 ;
DR   B5F1Y9, HPCH_SALA4 ;  A9MH59, HPCH_SALAR ;  Q57QP9, HPCH_SALCH ;
DR   B5FR34, HPCH_SALDC ;  Q9RPV0, HPCH_SALDU ;  B5R043, HPCH_SALEP ;
DR   B5R6F7, HPCH_SALG2 ;  B4TEM9, HPCH_SALHS ;  B4T2T9, HPCH_SALNS ;
DR   Q5PG96, HPCH_SALPA ;  A9N6T0, HPCH_SALPB ;  C0Q8A0, HPCH_SALPC ;
DR   B5BBH8, HPCH_SALPK ;  B4TSL7, HPCH_SALSV ;  Q8Z7P9, HPCH_SALTI ;
DR   Q8ZQ47, HPCH_SALTY ;  B2TZN1, HPCH_SHIB3 ;  Q31SY8, HPCH_SHIBS ;
DR   Q83P19, HPCH_SHIFL ;  Q3YU43, HPCH_SHISS ;
//
ID   4.1.2.n5
DE   2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase.
AN   ADH synthase.
CA   L-aspartate 4-semialdehyde + 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate
CA   = 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonate + hydroxypyruvaldehyde
CA   phosphate.
CC   -!- The enzyme plays a key role in an alternative pathway of the
CC       biosynthesis of 3-dehydroquinate (DHQ), which is involved in the
CC       canonical pathway for the biosynthesis of aromatic amino acids.
CC   -!- The enzyme can also catalyze the cleavage of fructose-1,6-
CC       bisphosphate to glyceraldehyde-3-phosphate and dihydroxyacetone
CC       phosphate.
DR   A6UTT2, ADHS_META3 ;  Q57843, ADHS_METJA ;  A4FYB3, ADHS_METM5 ;
DR   A9A799, ADHS_METM6 ;  A6VJZ0, ADHS_METM7 ;  Q6LZE3, ADHS_METMP ;
DR   A6USC8, ADHS_METVS ;
//
ID   4.1.3.1
DE   Isocitrate lyase.
AN   ICL.
AN   Isocitrase.
AN   Isocitratase.
AN   Isocitrate glyoxylate-lyase.
AN   Isocitritase.
CA   Isocitrate = succinate + glyoxylate.
CC   -!- The isomer of isocitrate involved is (1R,2S)-1-hydroxypropane-1,2,3-
CC       tricarboxylate.
PR   PROSITE; PDOC00145;
DR   P45456, ACEA1_SOYBN;  P45457, ACEA2_SOYBN;  P28467, ACEA_ACICA ;
DR   P28297, ACEA_ARATH ;  O94198, ACEA_ASHGO ;  Q6T267, ACEA_ASPFU ;
DR   Q9K9H0, ACEA_BACHD ;  P25248, ACEA_BRANA ;  Q9P8Q7, ACEA_CANAL ;
DR   Q6FPK7, ACEA_CANGA ;  P20014, ACEA_CANTR ;  Q96TP5, ACEA_COCIM ;
DR   A8NR45, ACEA_COPC7 ;  O13439, ACEA_COPCI ;  Q8RQN6, ACEA_COREF ;
DR   P42449, ACEA_CORGL ;  P93110, ACEA_CUCMA ;  P49296, ACEA_CUCSA ;
DR   Q9HFN2, ACEA_CYBJA ;  Q6BRY4, ACEA_DEBHA ;  Q9SE26, ACEA_DENCR ;
DR   P0A9G7, ACEA_ECOL6 ;  P0A9G6, ACEA_ECOLI ;  P28298, ACEA_EMENI ;
DR   Q4HYR2, ACEA_GIBZE ;  P17069, ACEA_GOSHI ;  P20699, ACEA_HELAN ;
DR   O50078, ACEA_HYPME ;  Q8NJ72, ACEA_KLULA ;  Q86ZF1, ACEA_LEPMC ;
DR   Q8J232, ACEA_MAGO7 ;  P0A5H4, ACEA_MYCBO ;  P46831, ACEA_MYCLE ;
DR   P0A5H3, ACEA_MYCTU ;  P28299, ACEA_NEUCR ;  Q96WZ5, ACEA_PENMA ;
DR   Q9C124, ACEA_PICPA ;  Q43097, ACEA_PINTA ;  Q9I0K4, ACEA_PSEAE ;
DR   P41554, ACEA_RHOFA ;  P15479, ACEA_RICCO ;  P51066, ACEA_SALTY ;
DR   P49297, ACEA_SOLLC ;  P41555, ACEA_YARLI ;  P28240, ACEA_YEAST ;
DR   Q10663, GCP_CAEEL  ;
//
ID   4.1.3.2
DE   Transferred entry: 2.3.3.9.
//
ID   4.1.3.3
DE   N-acetylneuraminate lyase.
AN   N-acetylneuraminate pyruvate-lyase.
AN   N-acetylneuraminic acid aldolase.
CA   N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate.
CC   -!- Also acts on N-glycoloylneuraminate, and on O-acetylated sialic
CC       acids, other than 4-O-acetylated derivatives.
PR   PROSITE; PDOC00569;
DR   Q8FD58, NANA1_ECOL6;  Q8FDU7, NANA2_ECOL6;  A3N352, NANA_ACTP2 ;
DR   B3GZ05, NANA_ACTP7 ;  B0BSI2, NANA_ACTPJ ;  A8AQB6, NANA_CITK8 ;
DR   Q0TUP8, NANA_CLOP1 ;  Q9S4K9, NANA_CLOPE ;  Q0SWI8, NANA_CLOPS ;
DR   A7ZSB8, NANA_ECO24 ;  B7UJV8, NANA_ECO27 ;  B7MBY7, NANA_ECO45 ;
DR   B7LHT3, NANA_ECO55 ;  P0A6L5, NANA_ECO57 ;  B5YSV2, NANA_ECO5E ;
DR   B7NKT6, NANA_ECO7I ;  B7M0T7, NANA_ECO8A ;  C4ZSW3, NANA_ECOBW ;
DR   B1XHJ8, NANA_ECODH ;  A8A535, NANA_ECOHS ;  A1AGB9, NANA_ECOK1 ;
DR   Q0TCP1, NANA_ECOL5 ;  B1IQQ4, NANA_ECOLC ;  P0A6L4, NANA_ECOLI ;
DR   B6I1U3, NANA_ECOSE ;  B1LGJ0, NANA_ECOSM ;  Q1R6B5, NANA_ECOUT ;
DR   A4WF38, NANA_ENT38 ;  B7LRJ3, NANA_ESCF3 ;  Q8RDN6, NANA_FUSNN ;
DR   P44539, NANA_HAEIN ;  Q0I2T8, NANA_HAES1 ;  B0UTI7, NANA_HAES2 ;
DR   P59407, NANA_LACPL ;  Q9CKB0, NANA_PASMU ;  Q92WP0, NANA_RHIME ;
DR   B5F7J9, NANA_SALA4 ;  A9MNY6, NANA_SALAR ;  Q57JC9, NANA_SALCH ;
DR   B5FIR8, NANA_SALDC ;  B5R0L2, NANA_SALEP ;  B5RET7, NANA_SALG2 ;
DR   B4TJR3, NANA_SALHS ;  B4T750, NANA_SALNS ;  Q5PLE9, NANA_SALPA ;
DR   A9N833, NANA_SALPB ;  C0PZN4, NANA_SALPC ;  B5BGP5, NANA_SALPK ;
DR   B4TWJ0, NANA_SALSV ;  Q8Z3F0, NANA_SALTI ;  Q8ZLQ6, NANA_SALTY ;
DR   B2U1V9, NANA_SHIB3 ;  Q31W94, NANA_SHIBS ;  Q32BB4, NANA_SHIDS ;
DR   Q0T065, NANA_SHIF8 ;  P0A6L6, NANA_SHIFL ;  Q3YX23, NANA_SHISS ;
DR   A7WXZ2, NANA_STAA1 ;  A6TY99, NANA_STAA2 ;  Q2FJU9, NANA_STAA3 ;
DR   Q2G160, NANA_STAA8 ;  A5IPI2, NANA_STAA9 ;  Q2YVB1, NANA_STAAB ;
DR   Q5HJ53, NANA_STAAC ;  A6QDU7, NANA_STAAE ;  P63949, NANA_STAAM ;
DR   P99123, NANA_STAAN ;  Q6GK01, NANA_STAAR ;  Q6GCF6, NANA_STAAS ;
DR   A8YZD9, NANA_STAAT ;  Q8NYC7, NANA_STAAW ;  B9DIJ2, NANA_STACT ;
DR   Q4L9T4, NANA_STAHJ ;  Q3B8E8, NPLA_XENLA ;  Q5XGL8, NPLB_XENLA ;
DR   Q29RY9, NPL_BOVIN  ;  Q5ZKD4, NPL_CHICK  ;  Q6NYR8, NPL_DANRE  ;
DR   Q9BXD5, NPL_HUMAN  ;  Q9DCJ9, NPL_MOUSE  ;  Q9BEC7, NPL_PIG    ;
DR   Q5RDY1, NPL_PONAB  ;  Q66H59, NPL_RAT    ;  Q5M905, NPL_XENTR  ;
//
ID   4.1.3.4
DE   Hydroxymethylglutaryl-CoA lyase.
AN   (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase.
AN   3-hydroxy-3-methylglutarate-CoA lyase.
AN   HMG-CoA lyase.
CA   (S)-3-hydroxy-3-methylglutaryl-CoA = acetyl-CoA + acetoacetate.
PR   PROSITE; PDOC00813;
DR   A8WG57, HMGC2_DANRE;  Q8TB92, HMGC2_HUMAN;  Q8JZS7, HMGC2_MOUSE;
DR   O81027, HMGCL_ARATH;  O34873, HMGCL_BACSU;  Q29448, HMGCL_BOVIN;
DR   P35915, HMGCL_CHICK;  P35914, HMGCL_HUMAN;  Q8HXZ6, HMGCL_MACFA;
DR   P38060, HMGCL_MOUSE;  Q5R9E1, HMGCL_PONAB;  P13703, HMGCL_PSEMV;
DR   P97519, HMGCL_RAT  ;
//
ID   4.1.3.5
DE   Transferred entry: 2.3.3.10.
//
ID   4.1.3.6
DE   Citrate (pro-3S)-lyase.
AN   Citrase.
AN   Citratase.
AN   Citrate aldolase.
AN   Citrate lyase.
AN   Citridesmolase.
AN   Citritase.
CA   Citrate = acetate + oxaloacetate.
CC   -!- Can be dissociated into components, two of which are identical with
CC       EC 2.8.3.10 and EC 4.1.3.34.
CC   -!- EC 3.1.2.16 deacetylates and inactivates the enzyme.
DR   P75726, CILA_ECOLI ;  P44459, CILA_HAEIN ;  P45413, CILA_KLEPN ;
DR   O53079, CILA_LEUMC ;  P0A9I2, CITE_ECOL6 ;  P0A9I1, CITE_ECOLI ;
DR   P44460, CITE_HAEIN ;  P17725, CITE_KLEPN ;  O53078, CITE_LEUMC ;
//
ID   4.1.3.7
DE   Transferred entry: 2.3.3.1.
//
ID   4.1.3.8
DE   Transferred entry: 2.3.3.8.
//
ID   4.1.3.9
DE   Transferred entry: 2.3.3.11.
//
ID   4.1.3.10
DE   Transferred entry: 2.3.3.7.
//
ID   4.1.3.11
DE   Transferred entry: 2.3.3.12.
//
ID   4.1.3.12
DE   Transferred entry: 2.3.3.13.
//
ID   4.1.3.13
DE   Oxalomalate lyase.
AN   3-oxalomalate glyoxylate-lyase.
CA   3-oxalomalate = oxaloacetate + glyoxylate.
//
ID   4.1.3.14
DE   L-erythro-3-hydroxyaspartate aldolase.
AN   Erythro-3-hydroxy-L(s)-aspartate glyoxylate-lyase.
CA   L-erythro-3-hydroxy-aspartate = glycine + glyoxylate.
//
ID   4.1.3.15
DE   Transferred entry: 2.2.1.5.
//
ID   4.1.3.16
DE   4-hydroxy-2-oxoglutarate aldolase.
AN   2-keto-4-hydroxyglutarate aldolase.
AN   2-oxo-4-hydroxyglutarate aldolase.
AN   4-hydroxy-2-oxoglutarate glyoxylate-lyase.
AN   KHG-aldolase.
CA   4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate.
CC   -!- Acts on both stereoisomers.
CC   -!- Formerly EC 4.1.2.1 and EC 4.1.2.31.
PR   PROSITE; PDOC00144;
DR   P50846, ALKH_BACSU ;  P38448, ALKH_DICD3 ;  P0A957, ALKH_ECO57 ;
DR   P0A956, ALKH_ECOL6 ;  P0A955, ALKH_ECOLI ;  P44480, ALKH_HAEIN ;
DR   P0A958, ALKH_SHIFL ;  O83578, ALKH_TREPA ;  Q00384, ALKH_ZYMMO ;
DR   Q9AQI0, HMGA_PSEOC ;  Q0P5I5, HOGA1_BOVIN;  P0CL20, HOGA1_COCIM;
DR   Q6NY77, HOGA1_DANRE;  Q5BD77, HOGA1_EMENI;  Q86XE5, HOGA1_HUMAN;
DR   Q9DCU9, HOGA1_MOUSE;  Q5XGL6, HOGA1_XENLA;  Q5M8W9, HOGA1_XENTR;
//
ID   4.1.3.17
DE   4-hydroxy-4-methyl-2-oxoglutarate aldolase.
AN   4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase.
CA   4-hydroxy-4-methyl-2-oxoglutarate = 2 pyruvate.
CC   -!- Also acts on 4-hydroxy-4-methyl-2-oxoadipate and 4-carboxy-4-hydroxy-
CC       2-oxohexadioate.
DR   Q9AQI0, HMGA_PSEOC ;
//
ID   4.1.3.18
DE   Transferred entry: 2.2.1.6.
//
ID   4.1.3.19
DE   Transferred entry: 2.5.1.56.
//
ID   4.1.3.20
DE   Transferred entry: 2.5.1.57.
//
ID   4.1.3.21
DE   Transferred entry: 2.3.3.14.
//
ID   4.1.3.22
DE   Citramalate lyase.
AN   (3S)-citramalate pyruvate-lyase.
CA   (3S)-citramalate = acetate + pyruvate.
CC   -!- Can be dissociated into components, two of which are identical with
CC       EC 2.8.3.11 and EC 4.1.3.25.
DR   Q05957, PDP_DIACA  ;
//
ID   4.1.3.23
DE   Transferred entry: 2.3.3.2.
//
ID   4.1.3.24
DE   Malyl-CoA lyase.
AN   (3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase.
AN   Malyl-coenzyme A lyase.
CA   (3S)-3-carboxy-3-hydroxypropanoyl-CoA = acetyl-CoA + glyoxylate.
DR   B6E2X2, MCAL_RHOCA ;  D5AR83, MCAL_RHOCB ;  A3PGR7, MCAL_RHOS1 ;
DR   Q3J5L6, MCAL_RHOS4 ;  A4WVF5, MCAL_RHOS5 ;  B9KLE8, MCAL_RHOSK ;
//
ID   4.1.3.25
DE   Citramalyl-CoA lyase.
AN   (3S)-citramalyl-CoA pyruvate-lyase.
CA   (3S)-citramalyl-CoA = acetyl-CoA + pyruvate.
CC   -!- Component of EC 4.1.3.22.
CC   -!- Also acts on (3S)-citramalyl thioacyl-carrier protein.
//
ID   4.1.3.26
DE   3-hydroxy-3-isohexenylglutaryl-CoA lyase.
AN   3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase.
CA   3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = 7-methyl-3-oxooct-6-
CA   enoyl-CoA + acetate.
CC   -!- Also acts on the hydroxy derivative of farnesoyl-CoA.
//
ID   4.1.3.27
DE   Anthranilate synthase.
CA   Chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate.
CC   -!- In some organisms, this enzyme is part of a multifunctional protein
CC       together with one or more components of the system for biosynthesis
CC       of tryptophan (EC 2.4.2.18, EC 4.1.1.48, EC 4.2.1.20,
CC       and EC 5.3.1.24).
CC   -!- The native enzyme in the complex with uses either glutamine or (less
CC       efficiently) NH(3).
CC   -!- The enzyme separated from the complex uses NH(3) only.
PR   PROSITE; PDOC00405;
DR   P28819, PABA_BACSU ;  P09785, PHNA_PSEAE ;  P09786, PHNB_PSEAE ;
DR   Q51519, PHZB_PSECL ;  Q51791, PHZE_PSEFL ;  P74130, TRE2_SYNY3 ;
DR   Q5V448, TRPE1_HALMA;  Q9HPG5, TRPE1_HALSA;  Q5V213, TRPE2_HALMA;
DR   Q9HS66, TRPE2_HALSA;  Q5V631, TRPE3_HALMA;  P23315, TRPE_ACICA ;
DR   Q9Y8T0, TRPE_AERPE ;  O66849, TRPE_AQUAE ;  P32068, TRPE_ARATH ;
DR   O28669, TRPE_ARCFU ;  P96556, TRPE_ARTGO ;  P50872, TRPE_AZOBR ;
DR   P30526, TRPE_BACCA ;  P18267, TRPE_BACPU ;  P03963, TRPE_BACSU ;
DR   Q44695, TRPE_BUCAI ;  P42387, TRPE_BUCAP ;  Q89A29, TRPE_BUCBP ;
DR   Q44697, TRPE_BUCDN ;  Q9ZER9, TRPE_BUCPS ;  Q44689, TRPE_BUCRM ;
DR   Q44691, TRPE_BUCRP ;  Q44598, TRPE_BUCSC ;  Q9ZES2, TRPE_BUCTC ;
DR   P00896, TRPE_CITFR ;  P14953, TRPE_CLOTM ;  P06557, TRPE_CORGL ;
DR   P00895, TRPE_ECOLI ;  Q9X6J4, TRPE_GEOSE ;  P43761, TRPE_HAEIN ;
DR   P33975, TRPE_HALVD ;  Q9ZJU5, TRPE_HELPJ ;  O25869, TRPE_HELPY ;
DR   Q02001, TRPE_LACLA ;  P20463, TRPE_LEPBI ;  Q58475, TRPE_METJA ;
DR   O27692, TRPE_METTH ;  P26940, TRPE_METTM ;  P67002, TRPE_MYCBO ;
DR   Q9X7C5, TRPE_MYCLE ;  A0QX93, TRPE_MYCS2 ;  P67001, TRPE_MYCTU ;
DR   Q5F8B4, TRPE_NEIG1 ;  Q9WW00, TRPE_NEIGO ;  Q9XAZ0, TRPE_NEIMA ;
DR   P56995, TRPE_NEIMB ;  Q9S358, TRPE_NEIMF ;  P20580, TRPE_PSEAE ;
DR   P20579, TRPE_PSEPU ;  P21689, TRPE_PSESS ;  Q9YGB3, TRPE_PYRKO ;
DR   P15395, TRPE_RHIME ;  P95646, TRPE_RHOS4 ;  P00898, TRPE_SALTY ;
DR   O94582, TRPE_SCHPO ;  P00897, TRPE_SERMA ;  P21690, TRPE_SPIAU ;
DR   Q9Z4W7, TRPE_STRCO ;  Q06128, TRPE_SULSO ;  P20170, TRPE_SYNY3 ;
DR   Q08653, TRPE_THEMA ;  P05378, TRPE_THET8 ;  Q9KST2, TRPE_VIBCH ;
DR   P22099, TRPE_VIBPA ;  P00899, TRPE_YEAST ;  Q5V214, TRPG1_HALMA;
DR   Q5V632, TRPG2_HALMA;  P00902, TRPG_ACIAD ;  O28670, TRPG_ARCFU ;
DR   P18483, TRPG_ASPAW ;  P05328, TRPG_ASPNG ;  P26922, TRPG_AZOBR ;
DR   Q44696, TRPG_BUCAI ;  P42388, TRPG_BUCAP ;  Q89A30, TRPG_BUCBP ;
DR   P14952, TRPG_CLOTM ;  Q92411, TRPG_COCHE ;  P06558, TRPG_CORGL ;
DR   P0CN87, TRPG_CRYNB ;  P0CN86, TRPG_CRYNJ ;  P27710, TRPG_CRYNV ;
DR   O19914, TRPG_CYACA ;  P48261, TRPG_CYAPA ;  P00904, TRPG_ECOLI ;
DR   P06531, TRPG_EMENI ;  P71381, TRPG_HAEIN ;  Q9HPG6, TRPG_HALSA ;
DR   P33974, TRPG_HALVD ;  Q9ZJU6, TRPG_HELPJ ;  O25868, TRPG_HELPY ;
DR   Q02003, TRPG_LACLA ;  P20441, TRPG_LEPBI ;  Q57690, TRPG_METJA ;
DR   O27693, TRPG_METTH ;  P26923, TRPG_METTM ;  Q7DAK6, TRPG_MYCTU ;
DR   P00908, TRPG_NEUCR ;  P24773, TRPG_PENCH ;  P25170, TRPG_PHACH ;
DR   P20409, TRPG_PHYBL ;  P09575, TRPG_PICAN ;  P51362, TRPG_PORPU ;
DR   Q1XDC5, TRPG_PORYE ;  P20576, TRPG_PSEAE ;  P00901, TRPG_PSEPU ;
DR   Q9YGB2, TRPG_PYRKO ;  P00905, TRPG_SALTY ;  Q92370, TRPG_SCHPO ;
DR   P00900, TRPG_SERMA ;  P00906, TRPG_SHIDY ;  Q06129, TRPG_SULSO ;
DR   Q08654, TRPG_THEMA ;  P05379, TRPG_THET8 ;  Q9KST3, TRPG_VIBCH ;
DR   P22101, TRPG_VIBPA ;  P00937, TRPG_YEAST ;  Q8ZEG6, TRPG_YERPE ;
DR   P32069, TRPX_ARATH ;  P44339, Y1171_HAEIN;
//
ID   4.1.3.28
DE   Transferred entry: 2.3.3.3.
//
ID   4.1.3.29
DE   Transferred entry: 2.3.3.4.
//
ID   4.1.3.30
DE   Methylisocitrate lyase.
AN   (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase.
CA   (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate.
CC   -!- Acts on threo-D(s)-2-methylisocitrate, but not on threo-D(s)-
CC       isocitrate, threo-DL-isocitrate or erythro-L(s)-isocitrate.
DR   Q9P6J1, ACEB_SCHPO ;  Q12031, ACEB_YEAST ;  Q8NSH8, PRPB1_CORGL;
DR   Q8NSL2, PRPB2_CORGL;  Q9YFM7, PRPB_AERPE ;  Q9Z9T7, PRPB_BACHD ;
DR   P54528, PRPB_BACSU ;  P77541, PRPB_ECOLI ;  Q56062, PRPB_SALTY ;
DR   Q9KSC2, PRPB_VIBCH ;
//
ID   4.1.3.31
DE   Transferred entry: 2.3.3.5.
//
ID   4.1.3.32
DE   2,3-dimethylmalate lyase.
AN   (2R,3S)-2,3-dimethylmalate pyruvate-lyase.
CA   (2R,3S)-2,3-dimethylmalate = propanoate + pyruvate.
CC   -!- Forms part of the nicotinate-fermentation catabolism pathway in
CC       Eubacterium barkeri.
CC   -!- Other enzymes involved in this pathway are EC 1.17.5.1, EC 1.3.7.1,
CC       EC 3.5.2.18, EC 1.1.1.291, EC 5.4.99.4, EC 5.3.3.6 and EC 4.2.1.85.
DR   Q0QLE4, DML_EUBBA  ;
//
ID   4.1.3.33
DE   Transferred entry: 2.3.3.6.
//
ID   4.1.3.34
DE   Citryl-CoA lyase.
AN   (3S)-citryl-CoA oxaloacetate-lyase.
CA   (3S)-citryl-CoA = acetyl-CoA + oxaloacetate.
CC   -!- Component of EC 4.1.3.6 and EC 4.1.3.8.
CC   -!- Also acts on (3S)-citryl thioacyl-carrier protein.
DR   P0A9I2, CITE_ECOL6 ;  P0A9I1, CITE_ECOLI ;  P44460, CITE_HAEIN ;
DR   P17725, CITE_KLEPN ;  O53078, CITE_LEUMC ;
//
ID   4.1.3.35
DE   (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase.
AN   (1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase.
CA   (1-hydroxycyclohexan-1-yl)acetyl-CoA = acetyl-CoA + cyclohexanone.
//
ID   4.1.3.36
DE   1,4-dihydroxy-2-naphthoyl-CoA synthase.
AN   DHNA synthetase.
AN   Dihydroxynaphthoic acid synthetase.
AN   Naphthoate synthase.
AN   o-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing).
CA   4-(2-carboxyphenyl)-4-oxobutanoyl-CoA = 1,4-dihydroxy-2-naphthoyl-CoA +
CA   H(2)O.
CC   -!- This enzyme is involved in the synthesis of 1,4-dihydroxy-2-
CC       naphthoate, a branch point metabolite leading to the biosynthesis of
CC       menaquinone (vitamin K(2), in bacteria), phylloquinone (vitamin K(1)
CC       in plants), and many plant pigments.
CC   -!- The coenzyme A group is subsequently removed from the product by
CC       EC 3.1.2.28.
PR   PROSITE; PDOC00150;
DR   Q8GYN9, MENB_ARATH ;  P23966, MENB_BACSU ;  Q9TM10, MENB_CYACA ;
DR   P0ABU1, MENB_ECOL6 ;  P0ABU0, MENB_ECOLI ;  P44960, MENB_HAEIN ;
DR   A0QRD3, MENB_MYCS2 ;  O06414, MENB_MYCTU ;  Q9CLV5, MENB_PASMU ;
DR   Q7CQ56, MENB_SALTY ;  Q5HH38, MENB_STAAC ;  Q99V48, MENB_STAAM ;
DR   Q7A6A9, MENB_STAAN ;  Q6GI37, MENB_STAAR ;  Q6GAG7, MENB_STAAS ;
DR   Q8NXA0, MENB_STAAW ;  Q5HQC3, MENB_STAEQ ;  Q8CPQ4, MENB_STAES ;
DR   Q4L549, MENB_STAHJ ;  Q49WG8, MENB_STAS1 ;
//
ID   4.1.3.37
DE   Transferred entry: 2.2.1.7.
//
ID   4.1.3.38
DE   Aminodeoxychorismate lyase.
AN   4-amino-4-deoxychorismate lyase.
AN   4-amino-4-deoxychorismate pyruvate-lyase.
AN   ADC lyase.
AN   Enzyme X.
CA   4-amino-4-deoxychorismate = 4-aminobenzoate + pyruvate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Forms part of the folate biosynthesis pathway.
CC   -!- Acts on 4-amino-4-deoxychorismate, the product of EC 2.6.1.85,
CC       to form p-aminobenzoate.
DR   P28821, PABC_BACSU ;  P28305, PABC_ECOLI ;  O42951, PABC_SCHPO ;
DR   Q9KQI0, PABC_VIBCH ;  Q56693, PABC_VIBHA ;  Q03266, PABC_YEAST ;
//
ID   4.1.3.39
DE   4-hydroxy-2-oxovalerate aldolase.
AN   4-hydroxy-2-ketovalerate aldolase.
AN   4-hydroxy-2-oxopentanoate pyruvate-lyase.
AN   4-hydroxy-2-oxovalerate pyruvate-lyase.
AN   HOA.
CA   4-hydroxy-2-oxopentanoate = acetaldehyde + pyruvate.
CF   Manganese.
CC   -!- In Pseudomonas species, this enzyme forms part of a bifunctional
CC       enzyme with EC 1.2.1.10.
CC   -!- Catalyzes the penultimate step in the meta-cleavage pathway for the
CC       degradation of phenols, methylphenols and catechol.
PR   PROSITE; PDOC50991;
DR   O05151, BPHF_RHOSR ;  O86013, BPHF_SPHAR ;  A1K6L9, HOA1_AZOSB ;
DR   C1DMT5, HOA1_AZOVD ;  B4EK78, HOA1_BURCJ ;  B2JLM6, HOA1_BURP8 ;
DR   Q397Q9, HOA1_BURS3 ;  A4JPX7, HOA1_BURVG ;  Q143P7, HOA1_BURXL ;
DR   Q9S152, HOA1_COMTE ;  Q0KAQ9, HOA1_CUPNH ;  Q47HL8, HOA1_DECAR ;
DR   A8LAA1, HOA1_FRASN ;  A2SI33, HOA1_METPP ;  B1MH40, HOA1_MYCA9 ;
DR   B2HGH1, HOA1_MYCMM ;  A0QZU2, HOA1_MYCS2 ;  A3Q4B9, HOA1_MYCSJ ;
DR   A1UM80, HOA1_MYCSK ;  Q1B2X1, HOA1_MYCSS ;  A0PR18, HOA1_MYCUA ;
DR   A1T2N6, HOA1_MYCVP ;  Q5Z2N2, HOA1_NOCFA ;  A1SH77, HOA1_NOCSJ ;
DR   A4XF35, HOA1_NOVAD ;  P51018, HOA1_PSEP1 ;  Q4F8H9, HOA1_PSEPS ;
DR   P51017, HOA1_PSEPU ;  B1J6Y7, HOA1_PSEPW ;  Q1LNS4, HOA1_RALME ;
DR   C0ZPX1, HOA1_RHOE4 ;  C1B7L0, HOA1_RHOOB ;  Q0SJD5, HOA1_RHOSR ;
DR   A8M1N0, HOA1_SALAI ;  A5V6T8, HOA1_SPHWW ;  A1K6Y4, HOA2_AZOSB ;
DR   C1DRJ0, HOA2_AZOVD ;  B4EFI7, HOA2_BURCJ ;  B2JQW0, HOA2_BURP8 ;
DR   Q396P0, HOA2_BURS3 ;  A4JW25, HOA2_BURVG ;  Q13VU3, HOA2_BURXL ;
DR   Q83VZ3, HOA2_COMTE ;  Q0K3S5, HOA2_CUPNH ;  Q47GC6, HOA2_DECAR ;
DR   A8LEP8, HOA2_FRASN ;  A2SL35, HOA2_METPP ;  B1MJT9, HOA2_MYCA9 ;
DR   B2HI25, HOA2_MYCMM ;  A0R4S6, HOA2_MYCS2 ;  A3Q6M9, HOA2_MYCSJ ;
DR   A1UQA1, HOA2_MYCSK ;  Q1B0P6, HOA2_MYCSS ;  A0PUX2, HOA2_MYCUA ;
DR   A1TDB7, HOA2_MYCVP ;  Q5YV93, HOA2_NOCFA ;  A1SIM3, HOA2_NOCSJ ;
DR   A4XDT6, HOA2_NOVAD ;  Q51983, HOA2_PSEP1 ;  Q52040, HOA2_PSEPS ;
DR   P51019, HOA2_PSEPU ;  B1J6Y1, HOA2_PSEPW ;  Q1LCQ8, HOA2_RALME ;
DR   C0ZU50, HOA2_RHOE4 ;  C1B8I0, HOA2_RHOOB ;  Q0S9W9, HOA2_RHOSR ;
DR   A8M6W8, HOA2_SALAI ;  A5V856, HOA2_SPHWW ;  A1K893, HOA3_AZOSB ;
DR   C1DN55, HOA3_AZOVD ;  Q390P6, HOA3_BURS3 ;  Q13QH6, HOA3_BURXL ;
DR   Q9RHN1, HOA3_COMTE ;  Q0K3N2, HOA3_CUPNH ;  Q47B13, HOA3_DECAR ;
DR   A1TFQ5, HOA3_MYCVP ;  Q5YUH4, HOA3_NOCFA ;  C1BAJ4, HOA3_RHOOB ;
DR   Q0S815, HOA3_RHOSR ;  A5VGU4, HOA3_SPHWW ;  C1DF10, HOA4_AZOVD ;
DR   Q39LH8, HOA4_BURS3 ;  P51015, HOA4_BURXL ;  Q479H0, HOA4_DECAR ;
DR   C1AVG2, HOA4_RHOOB ;  Q0S4F8, HOA4_RHOSR ;  Q479E5, HOA5_DECAR ;
DR   C1AYB4, HOA5_RHOOB ;  Q0S006, HOA5_RHOSR ;  C1BE28, HOA6_RHOOB ;
DR   Q0RXC3, HOA6_RHOSR ;  Q0RWN1, HOA7_RHOSR ;  A1W2K3, HOA_ACISJ  ;
DR   B9JML6, HOA_AGRRK  ;  Q0A5T5, HOA_ALHEH  ;  A0RD70, HOA_BACAH  ;
DR   Q739I4, HOA_BACC1  ;  C1ERL7, HOA_BACC3  ;  Q764S0, HOA_BACPJ  ;
DR   Q2KXU5, HOA_BORA1  ;  C0ZDU6, HOA_BREBN  ;  A3P825, HOA_BURP0  ;
DR   Q3JK55, HOA_BURP1  ;  A3NML2, HOA_BURP6  ;  B2T2S2, HOA_BURPP  ;
DR   Q63JB1, HOA_BURPS  ;  Q2T7S9, HOA_BURTA  ;  Q3ACM0, HOA_CARHZ  ;
DR   A9W9U3, HOA_CHLAA  ;  B8GBV5, HOA_CHLAD  ;  B9LCM1, HOA_CHLSY  ;
DR   Q46NW8, HOA_CUPPJ  ;  B2AIJ5, HOA_CUPTR  ;  B8G187, HOA_DESHD  ;
DR   A7ZI99, HOA_ECO24  ;  B7L508, HOA_ECO55  ;  Q8X5J8, HOA_ECO57  ;
DR   B5Z2Q7, HOA_ECO5E  ;  B7NK03, HOA_ECO7I  ;  B7MPB9, HOA_ECO81  ;
DR   B7M300, HOA_ECO8A  ;  A7ZWZ9, HOA_ECOHS  ;  B1J0S7, HOA_ECOLC  ;
DR   P51020, HOA_ECOLI  ;  B7N8Q9, HOA_ECOLU  ;  B6HZX8, HOA_ECOSE  ;
DR   B1LIN7, HOA_ECOSM  ;  Q6D796, HOA_ERWCT  ;  B0VXM7, HOA_GEOSE  ;
DR   A4IT42, HOA_GEOTN  ;  B5XQJ4, HOA_KLEP3  ;  A6TAC4, HOA_KLEP7  ;
DR   B1Y2E5, HOA_LEPCP  ;  A6W1X1, HOA_MARMS  ;  B8ESV2, HOA_METSB  ;
DR   Q2RHL3, HOA_MOOTA  ;  A0QAG9, HOA_MYCA1  ;  Q7TW97, HOA_MYCBO  ;
DR   A1KPL9, HOA_MYCBP  ;  C1AHZ2, HOA_MYCBT  ;  A4T7U4, HOA_MYCGI  ;
DR   Q743Q8, HOA_MYCPA  ;  A5U8K8, HOA_MYCTA  ;  P71867, HOA_MYCTU  ;
DR   A5D523, HOA_PELTS  ;  A1VUV1, HOA_POLNA  ;  Q120N9, HOA_POLSJ  ;
DR   Q3IEQ9, HOA_PSEHT  ;  P51014, HOA_PSES1  ;  Q9KWS0, HOA_PSESP  ;
DR   Q9ZI56, HOA_PSEST  ;  P51016, HOA_PSEUF  ;  B2UJF1, HOA_RALPJ  ;
DR   Q8XRF9, HOA_RALSO  ;  Q221U7, HOA_RHOFD  ;  A7NLU2, HOA_ROSCS  ;
DR   A5UWE6, HOA_ROSS1  ;  A4XAK7, HOA_SALTO  ;  A8GG86, HOA_SERP5  ;
DR   B0TTS9, HOA_SHEHH  ;  A8H4E9, HOA_SHEPA  ;  B1KJK9, HOA_SHEWM  ;
DR   Q3Z554, HOA_SHISS  ;  O85977, HOA_SPHAR  ;  A2TC45, HOA_SPHYA  ;
DR   Q0PHX9, HOA_SPIAU  ;  Q99PZ1, HOA_STRCO  ;  B1VRH5, HOA_STRGG  ;
DR   Q9X9Q0, HOA_STRTE  ;  B9L2J0, HOA_THERP  ;  Q53WI0, HOA_THET8  ;
DR   A1WLL2, HOA_VEREI  ;  A7IDU6, HOA_XANP2  ;
//
ID   4.1.3.40
DE   Chorismate lyase.
AN   CL.
AN   CPL.
CA   Chorismate = 4-hydroxybenzoate + pyruvate.
CC   -!- Catalyzes the first step in the biosynthesis of ubiquinone in
CC       Escherichia coli and other Gram-negative bacteria.
CC   -!- The yeast Saccharomyces cerevisiae can synthesize ubiquinone from
CC       either chorismate or tyrosine.
DR   Q3JJ81, UBIC1_BURP1;  Q1I4M5, UBIC1_PSEE4;  Q3KIF2, UBIC1_PSEPF;
DR   Q3JUM4, UBIC2_BURP1;  Q1I2R4, UBIC2_PSEE4;  Q3K4G4, UBIC2_PSEPF;
DR   Q6F9N7, UBIC_ACIAD ;  A3M775, UBIC_ACIBT ;  A0KEP8, UBIC_AERHH ;
DR   A4STB6, UBIC_AERS4 ;  Q0VTA8, UBIC_ALCBS ;  Q0A5V8, UBIC_ALHEH ;
DR   Q5P5L9, UBIC_AROAE ;  A1K2P0, UBIC_AZOSB ;  A1UTE7, UBIC_BARBK ;
DR   Q6G5M1, UBIC_BARHE ;  Q6FZ67, UBIC_BARQU ;  A9IWF5, UBIC_BART1 ;
DR   Q2L1H6, UBIC_BORA1 ;  Q7WJH0, UBIC_BORBR ;  Q7WAC9, UBIC_BORPA ;
DR   Q7VZD6, UBIC_BORPE ;  Q1BUR8, UBIC_BURCA ;  A0K9B9, UBIC_BURCH ;
DR   Q0BD35, UBIC_BURCM ;  Q62ID2, UBIC_BURMA ;  Q63W06, UBIC_BURPS ;
DR   Q39E37, UBIC_BURS3 ;  Q2SZY9, UBIC_BURTA ;  Q142T1, UBIC_BURXL ;
DR   Q1QSG3, UBIC_CHRSD ;  A8AN89, UBIC_CITK8 ;  Q48AM0, UBIC_COLP3 ;
DR   Q83F94, UBIC_COXBU ;  Q0K6Y1, UBIC_CUPNH ;  Q46XB3, UBIC_CUPPJ ;
DR   Q47AZ9, UBIC_DECAR ;  A7ZUR1, UBIC_ECO24 ;  B7UPK0, UBIC_ECO27 ;
DR   B7MJ29, UBIC_ECO45 ;  B7LAY7, UBIC_ECO55 ;  Q8XEC3, UBIC_ECO57 ;
DR   B5Z180, UBIC_ECO5E ;  B7NS03, UBIC_ECO7I ;  B7N2P6, UBIC_ECO81 ;
DR   B7M7V2, UBIC_ECO8A ;  C5A132, UBIC_ECOBW ;  B1XC38, UBIC_ECODH ;
DR   A8A7D9, UBIC_ECOHS ;  A1AIL6, UBIC_ECOK1 ;  Q0TA23, UBIC_ECOL5 ;
DR   Q8FB35, UBIC_ECOL6 ;  B1IUL3, UBIC_ECOLC ;  P26602, UBIC_ECOLI ;
DR   B7NFY3, UBIC_ECOLU ;  B6I5Q4, UBIC_ECOSE ;  B1LPK4, UBIC_ECOSM ;
DR   Q1R3P7, UBIC_ECOUT ;  A4W5F2, UBIC_ENT38 ;  A7MPN9, UBIC_ENTS8 ;
DR   Q6D9I9, UBIC_ERWCT ;  B2VKA5, UBIC_ERWT9 ;  A1WVN0, UBIC_HALHL ;
DR   C4K6Q1, UBIC_HAMD5 ;  Q5QUP2, UBIC_IDILO ;  B5XXZ3, UBIC_KLEP3 ;
DR   A6TGU8, UBIC_KLEP7 ;  A1U6P4, UBIC_MARAV ;  Q609A0, UBIC_METCA ;
DR   Q1GXB4, UBIC_METFK ;  Q0AGZ8, UBIC_NITEC ;  Q82TP3, UBIC_NITEU ;
DR   Q2Y5S2, UBIC_NITMU ;  Q9CMB5, UBIC_PASMU ;  C6DKC8, UBIC_PECCP ;
DR   Q7MZB5, UBIC_PHOLL ;  Q6LVS4, UBIC_PHOPR ;  B4EYR7, UBIC_PROMH ;
DR   Q48BQ6, UBIC_PSE14 ;  Q15ZU0, UBIC_PSEA6 ;  Q02E05, UBIC_PSEAB ;
DR   Q9HTK1, UBIC_PSEAE ;  Q4K3M0, UBIC_PSEF5 ;  Q3IHW4, UBIC_PSEHT ;
DR   Q88C66, UBIC_PSEPK ;  Q9FD32, UBIC_PSEPU ;  Q87U40, UBIC_PSESM ;
DR   Q4ZLB5, UBIC_PSEU2 ;  Q4FUZ9, UBIC_PSYA2 ;  Q1QE02, UBIC_PSYCK ;
DR   A1T086, UBIC_PSYIN ;  Q1LIU6, UBIC_RALME ;  Q8XVQ0, UBIC_RALSO ;
DR   Q21U27, UBIC_RHOFD ;  B5F1Q2, UBIC_SALA4 ;  A9MH91, UBIC_SALAR ;
DR   Q57GZ4, UBIC_SALCH ;  B5FQQ7, UBIC_SALDC ;  B5QZ58, UBIC_SALEP ;
DR   B5R7T2, UBIC_SALG2 ;  B4TDL6, UBIC_SALHS ;  B4T1S8, UBIC_SALNS ;
DR   Q5PL18, UBIC_SALPA ;  A9N1L2, UBIC_SALPB ;  C0Q4D8, UBIC_SALPC ;
DR   B5BJV6, UBIC_SALPK ;  B4TQQ1, UBIC_SALSV ;  Q8Z1T7, UBIC_SALTI ;
DR   Q8ZKI0, UBIC_SALTY ;  A8GKB8, UBIC_SERP5 ;  A1SBR9, UBIC_SHEAM ;
DR   Q12T34, UBIC_SHEDO ;  Q08A04, UBIC_SHEFN ;  A3QJG1, UBIC_SHELP ;
DR   Q8EKG2, UBIC_SHEON ;  A0KRF0, UBIC_SHESA ;  Q0HP10, UBIC_SHESM ;
DR   Q0I0H9, UBIC_SHESR ;  A1RQ05, UBIC_SHESW ;  B2TX77, UBIC_SHIB3 ;
DR   Q31TU7, UBIC_SHIBS ;  Q327U6, UBIC_SHIDS ;  Q0SXQ6, UBIC_SHIF8 ;
DR   Q83IP6, UBIC_SHIFL ;  Q3YUU5, UBIC_SHISS ;  Q2NR06, UBIC_SODGM ;
DR   Q31DN1, UBIC_THICR ;  Q3SLJ3, UBIC_THIDA ;  Q9KVP6, UBIC_VIBCH ;
DR   Q5E206, UBIC_VIBF1 ;  Q87KM8, UBIC_VIBPA ;  Q8DD50, UBIC_VIBVU ;
DR   Q7MQ88, UBIC_VIBVY ;  Q70C33, UBIC_XANAL ;  A1JRU5, UBIC_YERE8 ;
DR   A7FNA0, UBIC_YERP3 ;  Q1C0T7, UBIC_YERPA ;  B2K1U3, UBIC_YERPB ;
DR   Q8ZJ20, UBIC_YERPE ;  A9QYL0, UBIC_YERPG ;  Q1CE94, UBIC_YERPN ;
DR   A4TRU9, UBIC_YERPP ;  Q66FH1, UBIC_YERPS ;  B1JNE7, UBIC_YERPY ;
//
ID   4.1.3.41
DE   3-hydroxy-D-aspartate aldolase.
AN   D-3-hydroxyaspartate aldolase.
CA   (1) Threo-3-hydroxy-D-aspartate = glycine + glyoxylate.
CA   (2) D-erythro-3-hydroxyaspartate = glycine + glyoxylate.
CF   Pyridoxal 5'-phosphate.
CC   -!- The enzyme, purified from the bacterium Paracoccus denitrificansy IFO
CC       13301, is strictly D-specific as to the alpha-position of the
CC       substrate, but accepts both the threo and erythro forms at the beta-
CC       position.
CC   -!- The erythro form is a far better substrate (about 100 fold).
CC   -!- The enzyme can also accept D-allothreonine, D-threonine, erythro-3-
CC       phenyl-D-serine and threo-3-phenyl-D-serine.
CC   -!- Different from EC 4.1.3.14.
CC   -!- Requires a divalent cation, such as Mg(2+), Mn(2+) or Co(2+).
//
ID   4.1.99.1
DE   Tryptophanase.
AN   L-tryptophan indole-lyase.
AN   TNase.
CA   L-tryptophan + H(2)O = indole + pyruvate + NH(3).
CF   Potassium; Pyridoxal 5'-phosphate.
CC   -!- Also catalyzes 2,3-elimination and beta-replacement reactions of some
CC       indole-substituted tryptophan analogs of L-cysteine, L-serine and
CC       other 3-substituted amino acids.
PR   PROSITE; PDOC00667;
DR   P31014, TNAA1_SYMTH;  P31015, TNAA2_SYMTH;  A0KJP3, TNAA_AERHH ;
DR   Q9YCI2, TNAA_AERPE ;  A4SNA7, TNAA_AERS4 ;  Q7NYV9, TNAA_CHRVO ;
DR   A8AKE2, TNAA_CITK8 ;  Q894M8, TNAA_CLOTE ;  Q729Z3, TNAA_DESVH ;
DR   A1VC86, TNAA_DESVV ;  A7ZTR3, TNAA_ECO24 ;  B7UMH5, TNAA_ECO27 ;
DR   B7MGC9, TNAA_ECO45 ;  B7L853, TNAA_ECO55 ;  Q8XB34, TNAA_ECO57 ;
DR   B5YXB2, TNAA_ECO5E ;  B7NR10, TNAA_ECO7I ;  B7N212, TNAA_ECO81 ;
DR   B7M560, TNAA_ECO8A ;  C4ZYY6, TNAA_ECOBW ;  B1X9T7, TNAA_ECODH ;
DR   A8A6H0, TNAA_ECOHS ;  Q0TB00, TNAA_ECOL5 ;  Q8FBV2, TNAA_ECOL6 ;
DR   B1IX30, TNAA_ECOLC ;  P0A853, TNAA_ECOLI ;  B7NF25, TNAA_ECOLU ;
DR   B6I3U1, TNAA_ECOSE ;  B1LL35, TNAA_ECOSM ;  Q59342, TNAA_ENTAE ;
DR   B7LK50, TNAA_ESCF3 ;  Q4QML4, TNAA_HAEI8 ;  O07674, TNAA_HAEIF ;
DR   Q0I3R5, TNAA_HAES1 ;  B0UTZ3, TNAA_HAES2 ;  B0R7Q6, TNAA_HALS3 ;
DR   Q9HMV2, TNAA_HALSA ;  Q0C406, TNAA_HYPNA ;  Q9CL27, TNAA_PASMU ;
DR   Q7N8C9, TNAA_PHOLL ;  Q9ZNA8, TNAA_PROIN ;  P28796, TNAA_PROVU ;
DR   O30971, TNAA_RHOCA ;  Q2S1V4, TNAA_SALRD ;  A8G097, TNAA_SHESH ;
DR   B2TUR7, TNAA_SHIB3 ;  Q0SYP7, TNAA_SHIF8 ;  P0A854, TNAA_SHIFL ;
DR   Q8R9K5, TNAA_THETN ;  A5EYI0, TNAA_VIBC3 ;  Q9KN05, TNAA_VIBCH ;
DR   C3LUI5, TNAA_VIBCM ;  Q87JQ6, TNAA_VIBPA ;  Q8D5Q4, TNAA_VIBVU ;
DR   Q7MCR1, TNAA_VIBVY ;  A1JJH3, TNAA_YERE8 ;
//
ID   4.1.99.2
DE   Tyrosine phenol-lyase.
AN   Beta-tyrosinase.
CA   L-tyrosine + H(2)O = phenol + pyruvate + NH(3).
CF   Pyridoxal 5'-phosphate.
CC   -!- Also slowly catalyzes pyruvate formation from D-tyrosine, S-methyl-L-
CC       cysteine, L-cysteine, L-serine and D-serine.
PR   PROSITE; PDOC00667;
DR   P31013, TPL_CITFR  ;  D9R201, TPL_CLOSW  ;  Q897C2, TPL_CLOTE  ;
DR   P31011, TPL_ENTAG  ;  P31012, TPL_ESCIN  ;  Q8RHM6, TPL_FUSNN  ;
DR   E6SFG5, TPL_INTC7  ;  B2J908, TPL_NOSP7  ;  Q9CMK9, TPL_PASMU  ;
DR   O08501, TPL_SYMS1  ;  Q08897, TPL_SYMTH  ;
//
ID   4.1.99.3
DE   Deoxyribodipyrimidine photo-lyase.
AN   DNA photolyase.
AN   Photoreactivating enzyme.
CA   Cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA).
CF   5,10-methenyltetrahydrofolate; FAD.
CC   -!- A flavoprotein containing a second chromophore group.
CC   -!- Catalyzes the reactivation by light of irradiated DNA.
CC   -!- A similar reactivation of irradiated RNA is probably due to a
CC       separate enzyme.
PR   PROSITE; PDOC00331;
PR   PROSITE; PDOC00832;
DR   Q9SB00, PHR_ARATH  ;  Q04449, PHR_BACPE  ;  P57386, PHR_BUCAI  ;
DR   Q89AJ9, PHR_BUCBP  ;  P34205, PHR_CARAU  ;  P00914, PHR_ECOLI  ;
DR   Q9HQ46, PHR_HALSA  ;  P12769, PHR_METTH  ;  P58818, PHR_METTM  ;
DR   P27526, PHR_NEUCR  ;  Q6F6A2, PHR_ORYSJ  ;  Q28811, PHR_POTTR  ;
DR   P25078, PHR_SALTY  ;  P12768, PHR_STRGR  ;  P05327, PHR_SYNP6  ;
DR   Q55081, PHR_SYNY3  ;  P61496, PHR_THET2  ;  P61497, PHR_THET8  ;
DR   Q9KNA8, PHR_VIBCH  ;  P05066, PHR_YEAST  ;
//
ID   4.1.99.4
DE   Transferred entry: 3.5.99.7.
//
ID   4.1.99.5
DE   Octadecanal decarbonylase.
CA   Octadecanal + O(2) + 2 NADPH = heptadecane + formate + H(2)O + 2 NADP(+).
CF   Iron.
CC   -!- Involved in the biosynthesis of alkanes.
CC   -!- The enzyme from the cyanobacterium Nostoc punctiforme PCC 73102 is
CC       only active in vitro in the presence of ferredoxin, ferredoxin
CC       reductase and NADPH, and produces mostly C(15) to C(17) alkanes.
CC   -!- The enzyme from pea (Pisum sativum) produces alkanes of chain length
CC       C18 to C32 and is inhibited by metal-chelating agents.
CC   -!- The substrate for this enzyme is formed by EC 1.2.1.80.
//
ID   4.1.99.6
DE   Transferred entry: 4.2.3.6.
//
ID   4.1.99.7
DE   Transferred entry: 4.2.3.9.
//
ID   4.1.99.8
DE   Transferred entry: 4.2.3.14.
//
ID   4.1.99.9
DE   Transferred entry: 4.2.3.15.
//
ID   4.1.99.10
DE   Transferred entry: 4.2.3.16.
//
ID   4.1.99.11
DE   Benzylsuccinate synthase.
CA   Toluene + fumarate = benzylsuccinate.
CC   -!- A glycyl radical enzyme that is inhibited by benzyl alcohol,
CC       benzaldehyde, phenylhydrazine and is inactivated by oxygen.
//
ID   4.1.99.12
DE   3,4-dihydroxy-2-butanone-4-phosphate synthase.
AN   DHBP synthase.
AN   L-3,4-dihydroxybutan-2-one-4-phosphate synthase.
CA   D-ribulose 5-phosphate = formate + L-3,4-dihydroxybutan-2-one
CA   4-phosphate.
CF   Magnesium.
CC   -!- The reaction involves an intramolecular skeletal rearrangement, with
CC       the bonds in D-ribulose 5-phosphate that connect C-3 and C-5 to C-4
CC       being broken, C-4 being removed as formate and reconnection of C-3
CC       and C-5.
CC   -!- The phosphorylated four-carbon product (L-3,4-dihydroxybutan-2-one
CC       4-phosphate) is an intermediate in the biosynthesis of riboflavin.
DR   Q5A3V6, RIB3_CANAL ;  Q8TG90, RIB3_MAGO7 ;  O60181, RIB3_SCHPO ;
DR   Q99258, RIB3_YEAST ;  A3MZA2, RIBBA_ACTP2;  B3H0P8, RIBBA_ACTP7;
DR   B0BTN8, RIBBA_ACTPJ;  P50855, RIBBA_ACTPL;  O66679, RIBBA_AQUAE;
DR   P47924, RIBBA_ARATH;  A7Z675, RIBBA_BACA2;  C3P7P7, RIBBA_BACAA;
DR   C3LIX7, RIBBA_BACAC;  A0RIB3, RIBBA_BACAH;  P51695, RIBBA_BACAM;
DR   Q81MB6, RIBBA_BACAN;  B7JLW6, RIBBA_BACC0;  Q731I5, RIBBA_BACC1;
DR   B7IWM5, RIBBA_BACC2;  C1EQY5, RIBBA_BACC3;  B7HAY4, RIBBA_BACC4;
DR   B7HNM8, RIBBA_BACC7;  A7GSD5, RIBBA_BACCN;  B9IWX4, RIBBA_BACCQ;
DR   Q818X6, RIBBA_BACCR;  Q635H0, RIBBA_BACCZ;  Q5LHT1, RIBBA_BACFN;
DR   Q64YT3, RIBBA_BACFR;  Q6HE54, RIBBA_BACHK;  Q5WH08, RIBBA_BACSK;
DR   P17620, RIBBA_BACSU;  Q8A528, RIBBA_BACTN;  A6KWQ7, RIBBA_BACV8;
DR   A9VG50, RIBBA_BACWK;  C0ZKW2, RIBBA_BREBN;  Q9PLJ5, RIBBA_CHLMU;
DR   Q9Z734, RIBBA_CHLPN;  O84736, RIBBA_CHLTR;  A0Q3H7, RIBBA_CLONN;
DR   O24752, RIBBA_CORAM;  A4QEG9, RIBBA_CORGB;  Q8NQ52, RIBBA_CORGL;
DR   Q11WK6, RIBBA_CYTH3;  C5D3N0, RIBBA_GEOSW;  A0QI09, RIBBA_MYCA1;
DR   B1MCA4, RIBBA_MYCA9;  P0A5V1, RIBBA_MYCBO;  A1KIK4, RIBBA_MYCBP;
DR   C1AN60, RIBBA_MYCBT;  A4TC13, RIBBA_MYCGI;  B2HP67, RIBBA_MYCMM;
DR   Q741F1, RIBBA_MYCPA;  A5U2B7, RIBBA_MYCTA;  P0A5V0, RIBBA_MYCTU;
DR   A0PPL6, RIBBA_MYCUA;  A1T8K1, RIBBA_MYCVP;  Q5YTP3, RIBBA_NOCFA;
DR   A6LHN0, RIBBA_PARD8;  Q3B2I6, RIBBA_PELLD;  B4SE30, RIBBA_PELPB;
DR   B2RIG7, RIBBA_PORG3;  Q7MWK9, RIBBA_PORGI;  B4S5Y8, RIBBA_PROA2;
DR   A4SFY4, RIBBA_PROVI;  C0ZZE5, RIBBA_RHOE4;  Q0S0K2, RIBBA_RHOSR;
DR   A8LY38, RIBBA_SALAI;  A4X639, RIBBA_SALTO;  Q5HF07, RIBBA_STAAC;
DR   Q99TA0, RIBBA_STAAM;  Q7A511, RIBBA_STAAN;  Q6GFT5, RIBBA_STAAR;
DR   Q6G8G1, RIBBA_STAAS;  Q8NW14, RIBBA_STAAW;  Q5HNE3, RIBBA_STAEQ;
DR   Q8CNU2, RIBBA_STAES;  Q4L7B1, RIBBA_STAHJ;  Q49YJ7, RIBBA_STAS1;
DR   Q0AXM5, RIBBA_SYNWW;  P74104, RIBBA_SYNY3;  Q9X2E6, RIBBA_THEMA;
DR   B0KAI2, RIBBA_THEP3;  B0K0Y9, RIBBA_THEPX;  B1H0I0, RIBBA_UNCTG;
DR   A0KHV1, RIBB_AERHH ;  A4SKH7, RIBB_AERS4 ;  Q8UE66, RIBB_AGRT5 ;
DR   O28173, RIBB_ARCFU ;  Q1LSL6, RIBB_BAUCH ;  Q7VQQ4, RIBB_BLOFL ;
DR   Q7WDL7, RIBB_BORBR ;  Q7W2M1, RIBB_BORPA ;  Q7VSF4, RIBB_BORPE ;
DR   B8D8L7, RIBB_BUCA5 ;  P57167, RIBB_BUCAI ;  Q8KA55, RIBB_BUCAP ;
DR   B8D6X1, RIBB_BUCAT ;  P59556, RIBB_BUCBP ;  Q9PHU4, RIBB_CAMJE ;
DR   B3EEP4, RIBB_CHLL2 ;  B3QWA4, RIBB_CHLT3 ;  Q7NQC4, RIBB_CHRVO ;
DR   A8APS7, RIBB_CITK8 ;  A7FXH7, RIBB_CLOB1 ;  A5I603, RIBB_CLOBH ;
DR   A7GHE0, RIBB_CLOBL ;  Q46TZ9, RIBB_CUPPJ ;  O68249, RIBB_DEHMU ;
DR   B8FLF4, RIBB_DESAA ;  C6BVV4, RIBB_DESAD ;  C0QJB0, RIBB_DESAH ;
DR   B8J4Q5, RIBB_DESDA ;  Q313P5, RIBB_DESDG ;  Q6AQE3, RIBB_DESPS ;
DR   A4J2L3, RIBB_DESRM ;  Q72B63, RIBB_DESVH ;  A1VD83, RIBB_DESVV ;
DR   A7ZRS4, RIBB_ECO24 ;  B7UIV5, RIBB_ECO27 ;  B7MAC3, RIBB_ECO45 ;
DR   B7LGI1, RIBB_ECO55 ;  P0A7J1, RIBB_ECO57 ;  B5YR87, RIBB_ECO5E ;
DR   B7NJQ5, RIBB_ECO7I ;  B7N0J6, RIBB_ECO81 ;  B7LZJ1, RIBB_ECO8A ;
DR   C4ZQV9, RIBB_ECOBW ;  B1XG46, RIBB_ECODH ;  A8A4J8, RIBB_ECOHS ;
DR   A1AFX0, RIBB_ECOK1 ;  Q0TD60, RIBB_ECOL5 ;  Q8FDH9, RIBB_ECOL6 ;
DR   B1ISB5, RIBB_ECOLC ;  P0A7J0, RIBB_ECOLI ;  B7ND35, RIBB_ECOLU ;
DR   B6I413, RIBB_ECOSE ;  B1LF38, RIBB_ECOSM ;  Q1R6T4, RIBB_ECOUT ;
DR   C5BHH8, RIBB_EDWI9 ;  A4WEI2, RIBB_ENT38 ;  A7MP95, RIBB_ENTS8 ;
DR   Q6D8S3, RIBB_ERWCT ;  B2VGK1, RIBB_ERWT9 ;  B7LQC3, RIBB_ESCF3 ;
DR   Q4QMD5, RIBB_HAEI8 ;  A5UDW2, RIBB_HAEIE ;  A5UHR8, RIBB_HAEIG ;
DR   P44866, RIBB_HAEIN ;  Q0I132, RIBB_HAES1 ;  B0UX44, RIBB_HAES2 ;
DR   C4K8P2, RIBB_HAMD5 ;  Q7VJN5, RIBB_HELHP ;  Q9ZL40, RIBB_HELPJ ;
DR   O25484, RIBB_HELPY ;  B5XU43, RIBB_KLEP3 ;  A6TE29, RIBB_KLEP7 ;
DR   Q65W81, RIBB_MANSM ;  Q8TT89, RIBB_METAC ;  Q60364, RIBB_METJA ;
DR   A2SQG6, RIBB_METLZ ;  Q8PW86, RIBB_METMA ;  O27543, RIBB_METTH ;
DR   Q9JU97, RIBB_NEIMA ;  Q9JZ77, RIBB_NEIMB ;  Q8CWF6, RIBB_OCEIH ;
DR   P57940, RIBB_PASMU ;  C6D9P9, RIBB_PECCP ;  Q3A668, RIBB_PELCD ;
DR   A1AKS6, RIBB_PELPD ;  Q02008, RIBB_PHOLE ;  Q7N0C8, RIBB_PHOLL ;
DR   P51962, RIBB_PHOPO ;  Q6LIW0, RIBB_PHOPR ;  B4EW41, RIBB_PROMH ;
DR   Q9HWX4, RIBB_PSEAE ;  Q3IKS6, RIBB_PSEHT ;  Q88QG4, RIBB_PSEPK ;
DR   Q882G0, RIBB_PSESM ;  Q8XQN1, RIBB_RALSO ;  Q2RS98, RIBB_RHORT ;
DR   B5F690, RIBB_SALA4 ;  A9MPW6, RIBB_SALAR ;  Q57JR5, RIBB_SALCH ;
DR   B5FHS9, RIBB_SALDC ;  B5QZ31, RIBB_SALEP ;  B5REF3, RIBB_SALG2 ;
DR   B4TI45, RIBB_SALHS ;  B4T665, RIBB_SALNS ;  Q5PMU5, RIBB_SALPA ;
DR   A9N5X2, RIBB_SALPB ;  C0PYW8, RIBB_SALPC ;  B5BG06, RIBB_SALPK ;
DR   B4TVS9, RIBB_SALSV ;  P66033, RIBB_SALTI ;  P66032, RIBB_SALTY ;
DR   A8GJU0, RIBB_SERP5 ;  B8E3W7, RIBB_SHEB2 ;  A3DAC1, RIBB_SHEB5 ;
DR   A6WHL6, RIBB_SHEB8 ;  A9KVB7, RIBB_SHEB9 ;  Q07WC1, RIBB_SHEFN ;
DR   B0TMY9, RIBB_SHEHH ;  A3Q8W5, RIBB_SHELP ;  Q8EKF2, RIBB_SHEON ;
DR   A8GYS3, RIBB_SHEPA ;  A4Y1N7, RIBB_SHEPC ;  B8CH19, RIBB_SHEPW ;
DR   A0KRF9, RIBB_SHESA ;  A8G1K1, RIBB_SHESH ;  Q0HP01, RIBB_SHESM ;
DR   Q0I0H0, RIBB_SHESR ;  A1RPZ7, RIBB_SHESW ;  B1KNY2, RIBB_SHEWM ;
DR   B2U1F0, RIBB_SHIB3 ;  Q31WZ1, RIBB_SHIBS ;  Q32BS1, RIBB_SHIDS ;
DR   Q0T0L7, RIBB_SHIF8 ;  P0A7J2, RIBB_SHIFL ;  Q3YXK0, RIBB_SHISS ;
DR   Q2NWD7, RIBB_SODGM ;  C4LDD2, RIBB_TOLAT ;  A5F159, RIBB_VIBC3 ;
DR   Q9KKP2, RIBB_VIBCH ;  C3LWX2, RIBB_VIBCM ;  Q9L6K8, RIBB_VIBFI ;
DR   P16448, RIBB_VIBHA ;  Q87GR5, RIBB_VIBPA ;  B7VT10, RIBB_VIBSL ;
DR   Q8D485, RIBB_VIBVU ;  Q7MFR0, RIBB_VIBVY ;  Q8D2W5, RIBB_WIGBR ;
DR   Q7M936, RIBB_WOLSU ;  A1JQV2, RIBB_YERE8 ;  A7FE82, RIBB_YERP3 ;
DR   Q1C377, RIBB_YERPA ;  B2K2H0, RIBB_YERPB ;  Q8ZI56, RIBB_YERPE ;
DR   A9R7D2, RIBB_YERPG ;  Q1CMD1, RIBB_YERPN ;  A4THU2, RIBB_YERPP ;
DR   Q665V6, RIBB_YERPS ;  B1JM30, RIBB_YERPY ;
//
ID   4.1.99.13
DE   (6-4)DNA photolyase.
AN   DNA photolyase.
CA   (6-4) photoproduct (in DNA) = 2 pyrimidine residues (in DNA).
CF   FAD.
CC   -!- The overall repair reaction consists of two distinct steps, one of
CC       which is light-independent and the other one light-dependent.
CC   -!- In the initial light-independent step, a 6-iminium ion is thought to
CC       be generated via proton transfer induced by two histidines highly
CC       conserved among the (6-4) photolyases.
CC   -!- This intermediate spontaneously rearranges to form an oxetane
CC       intermediate by intramolecular nucleophilic attack.
CC   -!- In the subsequent light-driven reaction, one electron is believed to
CC       be transferred from the fully reduced FAD cofactor (FADH(-)) to the
CC       oxetane intermediate thus forming a neutral FADH radical and an
CC       anionic oxetane radical, which spontaneously fractures.
CC   -!- The excess electron is then back-transferred to the flavin radical
CC       restoring the fully reduced flavin cofactor and a pair of pyrimidine
CC       bases.
PR   PROSITE; PDOC00331;
DR   O48652, UVR3_ARATH ;  Q0E2Y1, UVR3_ORYSJ ;
//
ID   4.1.99.14
DE   Spore photoproduct lyase.
AN   SP lyase.
CA   (5R)-5,6-dihydro-5-(thymidin-7-yl)thymidine (in double-helical DNA) =
CA   thymidylyl-(3'->5')-thymidylate (in double-helical DNA).
CF   Iron-sulfur and S-adenosyl-L-methionine.
CC   -!- This enzyme is a member of the 'AdoMet radical' (radical SAM) family.
CC   -!- The enzyme binds a [4Fe-4S]  cluster.
CC   -!- The cluster is coordinated by 3 cysteines and an exchangeable SAM
CC       molecule.
CC   -!- The 5'-deoxy-adenosine radical formed after electron transfer from
CC       the [4Fe-4S] cluster to the S-adenosyl-L-methionine, initiates the
CC       repair by abstracting the C-6 hydrogen of the spore photoproduct
CC       lesion.
CC   -!- During the second part of the repair process the SAM molecule is
CC       regenerated.
DR   Q97L63, SPLB_CLOAB ;  P37956, SPL_BACSU  ;  C9RZ55, SPL_GEOSY  ;
//
ID   4.1.99.15
DE   Deleted entry.
//
ID   4.1.99.16
DE   Geosmin synthase.
CA   (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + H(2)O = (-)-geosmin +
CA   acetone.
CF   Magnesium.
CC   -!- Geosmin is the cause of the characteristic smell of moist soil.
CC   -!- It is a bifunctional enzyme.
CC   -!- The N-terminal part of the enzyme is EC 4.2.3.22, germacradienol
CC       synthase, and forms germacradienol from FPP.
CC   -!- The C-terminal part of the enzyme catalyzes the conversion of
CC       germacradienol to geosmin via (1S,4aS,8aS)-8,10-dimethyl-
CC       1,2,3,4,4a,5,6,8a-octahydronaphthalene.
DR   Q9X839, CYC2_STRCO ;
//
ID   4.2.1.1
DE   Carbonate dehydratase.
AN   Carbonate hydro-lyase.
AN   Carbonic anhydrase.
AN   Carbonic dehydratase.
CA   H(2)CO(3) = CO(2) + H(2)O.
CF   Zinc.
PR   PROSITE; PDOC00146;
PR   PROSITE; PDOC00586;
DR   A8XKV0, BCA1_CAEBR ;  Q22460, BCA1_CAEEL ;  O43570, CAH12_HUMAN;
DR   Q8CI85, CAH12_MOUSE;  Q9MZ30, CAH12_RABIT;  Q8N1Q1, CAH13_HUMAN;
DR   Q9D6N1, CAH13_MOUSE;  Q9ULX7, CAH14_HUMAN;  Q9WVT6, CAH14_MOUSE;
DR   Q99N23, CAH15_MOUSE;  Q1LZA1, CAH1_BOVIN ;  P83299, CAH1_CHIHA ;
DR   P20507, CAH1_CHLRE ;  P46512, CAH1_FLALI ;  Q7M316, CAH1_GORGO ;
DR   P00917, CAH1_HORSE ;  P00915, CAH1_HUMAN ;  P00916, CAH1_MACMU ;
DR   P35217, CAH1_MACNE ;  Q8HY33, CAH1_MONDO ;  P13634, CAH1_MOUSE ;
DR   Q7M317, CAH1_PANTR ;  P07452, CAH1_RABIT ;  B0BNN3, CAH1_RAT   ;
DR   P48282, CAH1_SHEEP ;  P42737, CAH2_ARATH ;  P00921, CAH2_BOVIN ;
DR   P07630, CAH2_CHICK ;  P24258, CAH2_CHLRE ;  P46513, CAH2_FLALI ;
DR   P00918, CAH2_HUMAN ;  P00920, CAH2_MOUSE ;  P00919, CAH2_RABIT ;
DR   P27139, CAH2_RAT   ;  P00922, CAH2_SHEEP ;  Q8UWA5, CAH2_TRIHK ;
DR   Q3SZX4, CAH3_BOVIN ;  Q27504, CAH3_CAEEL ;  P07450, CAH3_HORSE ;
DR   P07451, CAH3_HUMAN ;  P16015, CAH3_MOUSE ;  Q5S1S4, CAH3_PIG   ;
DR   P14141, CAH3_RAT   ;  Q95323, CAH4_BOVIN ;  P22748, CAH4_HUMAN ;
DR   Q64444, CAH4_MOUSE ;  P48283, CAH4_RABIT ;  P48284, CAH4_RAT   ;
DR   P35218, CAH5A_HUMAN;  P23589, CAH5A_MOUSE;  P43165, CAH5A_RAT  ;
DR   Q9Y2D0, CAH5B_HUMAN;  Q9QZA0, CAH5B_MOUSE;  Q66HG6, CAH5B_RAT  ;
DR   Q10462, CAH5_CAEEL ;  P18915, CAH6_BOVIN ;  Q865C0, CAH6_CANFA ;
DR   P23280, CAH6_HUMAN ;  P18761, CAH6_MOUSE ;  P08060, CAH6_SHEEP ;
DR   P43166, CAH7_HUMAN ;  Q9ERQ8, CAH7_MOUSE ;  Q16790, CAH9_HUMAN ;
DR   Q8VHB5, CAH9_MOUSE ;  P27140, CAHC_ARATH ;  P40880, CAHC_HORVU ;
DR   P17067, CAHC_PEA   ;  P16016, CAHC_SPIOL ;  P27141, CAHC_TOBAC ;
DR   P46510, CAHX_FLABI ;  P46511, CAHX_FLABR ;  P46281, CAHX_FLAPR ;
DR   Q92051, CAHZ_DANRE ;  P54212, CAH_DUNSA  ;  O52538, CAH_ERWCA  ;
DR   Q6DAJ6, CAH_ERWCT  ;  O52535, CAH_KLEPN  ;  P84537, CAH_LOBCS  ;
DR   P40881, CAH_METTE  ;  Q50940, CAH_NEIGO  ;  P94170, CAH_NOSS1  ;
DR   P61517, CAN_ECOLI  ;  Q5BCC5, CAN_EMENI  ;  P45148, CAN_HAEIN  ;
DR   O94255, CAN_SCHPO  ;  P61518, CAN_SHIFL  ;  P53615, CAN_YEAST  ;
DR   P0ABF0, CYNT_ECO57 ;  P0ABE9, CYNT_ECOLI ;  Q9ZN54, CYNT_HELPJ ;
DR   O24855, CYNT_HELPY ;  A0R566, CYNT_MYCS2 ;  O53573, CYNT_MYCTU ;
DR   Q9I262, CYNT_PSEAE ;  P83329, CYNT_STRTR ;  P27134, CYNT_SYNE7 ;
DR   Q54735, CYNT_SYNY3 ;  Q9NL38, MA66_PINMA ;  A0ZSF6, MAC1_CRANI ;
DR   A0ZSF7, MAC2_CRANI ;  A0ZSF2, MAF_PINFU  ;  A0ZSF3, MAM_PINMA  ;
DR   Q27908, MANA_PINFU ;  A0ZSF4, MAP1_MIZYE ;  A0ZSF5, MAP2_MIZYE ;
DR   Q84UV8, NEC3_NICLS ;  O34872, YTIB_BACSU ;  O06983, YVDA_BACSU ;
//
ID   4.2.1.2
DE   Fumarate hydratase.
AN   Fumarase.
CA   (S)-malate = fumarate + H(2)O.
PR   PROSITE; PDOC00147;
DR   P93033, FUM1_ARATH ;  Q9FI53, FUM2_ARATH ;  Q8X4P8, FUMA_ECO57 ;
DR   P0AC34, FUMA_ECOL6 ;  P0AC33, FUMA_ECOLI ;  Q04718, FUMA_GEOSE ;
DR   Q58690, FUMA_METJA ;  P40720, FUMA_SALTY ;  P14407, FUMB_ECOLI ;
DR   Q58034, FUMB_METJA ;  P28894, FUMC1_BRAJA;  Q51404, FUMC1_PSEAE;
DR   Q89XM2, FUMC2_BRAJA;  Q9I587, FUMC2_PSEAE;  Q8UEY7, FUMC_AGRT5 ;
DR   Q81SA0, FUMC_BACAN ;  Q81F85, FUMC_BACCR ;  Q9KCX4, FUMC_BACHD ;
DR   P07343, FUMC_BACSU ;  Q7VR50, FUMC_BLOFL ;  Q7WG65, FUMC_BORBR ;
DR   Q7W4N9, FUMC_BORPA ;  Q7W0A2, FUMC_BORPE ;  Q8YB50, FUMC_BRUME ;
DR   Q8FX90, FUMC_BRUSU ;  O69294, FUMC_CAMJE ;  Q9A6I5, FUMC_CAUCR ;
DR   Q822D5, FUMC_CHLCV ;  Q9PL64, FUMC_CHLMU ;  Q9Z6P6, FUMC_CHLPN ;
DR   O84863, FUMC_CHLTR ;  Q7NZ02, FUMC_CHRVO ;  Q8FQP8, FUMC_COREF ;
DR   Q8NRN8, FUMC_CORGL ;  Q83CL8, FUMC_COXBU ;  Q9RR70, FUMC_DEIRA ;
DR   Q8X769, FUMC_ECO57 ;  Q8FHA7, FUMC_ECOL6 ;  P05042, FUMC_ECOLI ;
DR   Q7VKC9, FUMC_HAEDU ;  P71384, FUMC_HAEIN ;  Q9HQ29, FUMC_HALSA ;
DR   Q9ZJQ9, FUMC_HELPJ ;  O25883, FUMC_HELPY ;  Q72VY3, FUMC_LEPIC ;
DR   Q8F9L0, FUMC_LEPIN ;  Q929E8, FUMC_LISIN ;  Q71XE0, FUMC_LISMF ;
DR   Q8Y551, FUMC_LISMO ;  Q8TS07, FUMC_METAC ;  Q8KTE1, FUMC_METEA ;
DR   Q7U0N6, FUMC_MYCBO ;  O53446, FUMC_MYCTU ;  P95331, FUMC_MYXXD ;
DR   Q9JTR0, FUMC_NEIMA ;  Q82SM5, FUMC_NITEU ;  Q8CUH5, FUMC_OCEIH ;
DR   Q9CMK1, FUMC_PASMU ;  Q7N4H8, FUMC_PHOLL ;  Q7VA47, FUMC_PROMA ;
DR   Q7V5R2, FUMC_PROMM ;  Q7V024, FUMC_PROMP ;  Q88M20, FUMC_PSEPK ;
DR   Q885V0, FUMC_PSESM ;  Q8XQE8, FUMC_RALSO ;  Q983U5, FUMC_RHILO ;
DR   Q92PB6, FUMC_RHIME ;  Q1RHL6, FUMC_RICBR ;  Q92GW0, FUMC_RICCN ;
DR   Q4UMT4, FUMC_RICFE ;  Q9ZCQ4, FUMC_RICPR ;  Q68W74, FUMC_RICTY ;
DR   Q8Z6R6, FUMC_SALTI ;  Q8ZPL7, FUMC_SALTY ;  Q83ML8, FUMC_SHIFL ;
DR   Q5HES4, FUMC_STAAC ;  P64172, FUMC_STAAM ;  P64173, FUMC_STAAN ;
DR   Q6GFK5, FUMC_STAAR ;  Q6G884, FUMC_STAAS ;  Q8NVV1, FUMC_STAAW ;
DR   Q5HN85, FUMC_STAEQ ;  Q8CNR1, FUMC_STAES ;  Q4L7F5, FUMC_STAHJ ;
DR   Q49YP8, FUMC_STAS1 ;  Q82ID7, FUMC_STRAW ;  Q9FBN6, FUMC_STRCO ;
DR   P39461, FUMC_SULSO ;  Q7U8I1, FUMC_SYNPX ;  Q55674, FUMC_SYNY3 ;
DR   Q60022, FUMC_THEAQ ;  Q8DIP7, FUMC_THEEB ;  O66271, FUMC_THET2 ;
DR   Q8D2L3, FUMC_WIGBR ;  Q9PD25, FUMC_XYLFA ;  Q87DC2, FUMC_XYLFT ;
DR   Q8ZEB6, FUMC_YERPE ;  O17214, FUMH_CAEEL ;  Q7SX99, FUMH_DANRE ;
DR   Q54VA2, FUMH_DICDI ;  P07954, FUMH_HUMAN ;  Q60HF9, FUMH_MACFA ;
DR   P97807, FUMH_MOUSE ;  P10173, FUMH_PIG   ;  P14408, FUMH_RAT   ;
DR   P55250, FUMH_RHIOR ;  O94552, FUMH_SCHPO ;  P08417, FUMH_YEAST ;
//
ID   4.2.1.3
DE   Aconitate hydratase.
AN   Aconitase.
AN   Cis-aconitase.
AN   Citrate hydro-lyase.
AN   Citrate(isocitrate) hydro-lyase.
CA   Citrate = isocitrate.
CF   Iron-sulfur.
CC   -!- Besides interconverting citrate and cis-aconitate, it also
CC       interconverts cis-aconitate with isocitrate and, hence, interconverts
CC       citrate and isocitrate.
CC   -!- The equilibrium mixture is 91% citrate, 6% isocitrate and 3%
CC       aconitate.
CC   -!- Cis-aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3-
CC       tricarboxylate.
PR   PROSITE; PDOC00423;
DR   Q42560, ACO1_ARATH ;  Q9SIB9, ACO2M_ARATH;  Q94A28, ACO3M_ARATH;
DR   Q0VCU1, ACOC_BOVIN ;  Q23500, ACOC_CAEEL ;  Q90875, ACOC_CHICK ;
DR   P49608, ACOC_CUCMA ;  Q42669, ACOC_CUCMC ;  Q54X73, ACOC_DICDI ;
DR   P21399, ACOC_HUMAN ;  P28271, ACOC_MOUSE ;  Q6YZX6, ACOC_ORYSJ ;
DR   Q01059, ACOC_RABIT ;  Q63270, ACOC_RAT   ;  O04916, ACOC_SOLTU ;
DR   P25516, ACON1_ECOLI;  Q9I3F5, ACON1_PSEAE;  P36683, ACON2_ECOLI;
DR   Q9ZL64, ACON2_HELPJ;  P56418, ACON2_HELPY;  Q9I2V5, ACON2_PSEAE;
DR   Q9P7D4, ACON2_SCHPO;  P74582, ACON2_SYNY3;  P39533, ACON2_YEAST;
DR   P09339, ACON_BACSU ;  P20004, ACON_BOVIN ;  P70920, ACON_BRAJA ;
DR   P34455, ACON_CAEEL ;  P82611, ACON_CANAL ;  Q6NH63, ACON_CORDI ;
DR   Q8FTA8, ACON_COREF ;  Q8NQ98, ACON_CORGL ;  Q4JVM4, ACON_CORJK ;
DR   Q9RTN7, ACON_DEIRA ;  Q54XS2, ACON_DICDI ;  Q2A1K3, ACON_FRATH ;
DR   P49609, ACON_GRAVE ;  Q99798, ACON_HUMAN ;  P37032, ACON_LEGPH ;
DR   Q99KI0, ACON_MOUSE ;  O08451, ACON_MYCAV ;  A0QX20, ACON_MYCS2 ;
DR   P16276, ACON_PIG   ;  Q9ER34, ACON_RAT   ;  Q1RKD5, ACON_RICBR ;
DR   Q92G90, ACON_RICCN ;  Q4UK20, ACON_RICFE ;  Q9ZCF4, ACON_RICPR ;
DR   Q68VV0, ACON_RICTY ;  O13966, ACON_SCHPO ;  Q5HG69, ACON_STAAC ;
DR   P63433, ACON_STAAM ;  P99148, ACON_STAAN ;  Q6GH55, ACON_STAAR ;
DR   Q6G9K9, ACON_STAAS ;  P63434, ACON_STAAW ;  Q5HPJ0, ACON_STAEQ ;
DR   Q8CPC2, ACON_STAES ;  Q59938, ACON_STRMU ;  P19414, ACON_YEAST ;
//
ID   4.2.1.4
DE   Citrate dehydratase.
AN   Citrate hydro-lyase.
CA   Citrate = cis-aconitate + H(2)O.
CC   -!- Cis-aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3-
CC       tricarboxylate.
CC   -!- Does not act on isocitrate.
//
ID   4.2.1.5
DE   Arabinonate dehydratase.
AN   D-arabinonate hydro-lyase.
CA   D-arabinonate = 2-dehydro-3-deoxy-D-arabinonate + H(2)O.
//
ID   4.2.1.6
DE   Galactonate dehydratase.
CA   D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H(2)O.
DR   B1LPS5, DGOD1_ECOSM;  B1LL17, DGOD2_ECOSM;  A7ZTP7, DGOD_ECO24 ;
DR   B7MGB3, DGOD_ECO45 ;  B7L836, DGOD_ECO55 ;  B7NQZ2, DGOD_ECO7I ;
DR   B7N1Z6, DGOD_ECO81 ;  B7M4I1, DGOD_ECO8A ;  C4ZYW9, DGOD_ECOBW ;
DR   B1X9C1, DGOD_ECODH ;  A8A6F2, DGOD_ECOHS ;  A1AHM7, DGOD_ECOK1 ;
DR   Q0TB15, DGOD_ECOL5 ;  B1IYQ2, DGOD_ECOLC ;  Q6BF17, DGOD_ECOLI ;
DR   B7NF09, DGOD_ECOLU ;  B6I3S5, DGOD_ECOSE ;  Q1R4P4, DGOD_ECOUT ;
DR   A4W4R9, DGOD_ENT38 ;  A7MN07, DGOD_ENTS8 ;  Q6CYT9, DGOD_ERWCT ;
DR   B7LK34, DGOD_ESCF3 ;  B5XW18, DGOD_KLEP3 ;  A6TFZ4, DGOD_KLEP7 ;
DR   B2UCA8, DGOD_RALPJ ;  Q8XVS8, DGOD_RALSO ;  Q57I11, DGOD_SALCH ;
DR   B5FN00, DGOD_SALDC ;  B5QUN9, DGOD_SALEP ;  B5RFZ8, DGOD_SALG2 ;
DR   B4TA81, DGOD_SALHS ;  B4SY97, DGOD_SALNS ;  A9MWL9, DGOD_SALPB ;
DR   B5BIK9, DGOD_SALPK ;  Q8ZKZ1, DGOD_SALTY ;  A8G7R4, DGOD_SERP5 ;
DR   C5CZC3, DGOD_VARPS ;  A1WPC7, DGOD_VEREI ;  Q8PLN0, DGOD_XANAC ;
DR   Q3BUN6, DGOD_XANC5 ;  Q4UTT5, DGOD_XANC8 ;  B0RTW1, DGOD_XANCB ;
DR   Q8P9V1, DGOD_XANCP ;  Q2P1Q3, DGOD_XANOM ;  B2SV55, DGOD_XANOP ;
//
ID   4.2.1.7
DE   Altronate dehydratase.
CA   D-altronate = 2-dehydro-3-deoxy-D-gluconate + H(2)O.
DR   O34673, UXAA_BACSU ;  P42604, UXAA_ECOLI ;
//
ID   4.2.1.8
DE   Mannonate dehydratase.
AN   Altronate hydrolase.
AN   D-mannonate hydro-lyase.
AN   Mannonic hydrolase.
CA   D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H(2)O.
DR   Q8UAW0, UXUA1_AGRT5;  Q9KDZ8, UXUA1_BACHD;  Q65L04, UXUA1_BACLD;
DR   Q8UA46, UXUA2_AGRT5;  Q9KEZ3, UXUA2_BACHD;  Q65IW0, UXUA2_BACLD;
DR   Q5LIV6, UXUA_BACFN ;  Q650A0, UXUA_BACFR ;  Q5WKD5, UXUA_BACSK ;
DR   O34346, UXUA_BACSU ;  Q8A7U2, UXUA_BACTN ;  C0QWB0, UXUA_BRAHW ;
DR   A9MCA1, UXUA_BRUC2 ;  C0RLW2, UXUA_BRUMB ;  Q8YCQ4, UXUA_BRUME ;
DR   A9WZA3, UXUA_BRUSI ;  Q8FVM2, UXUA_BRUSU ;  B4EKS2, UXUA_BURCJ ;
DR   B2TGB8, UXUA_BURPP ;  Q396Y9, UXUA_BURS3 ;  Q1QT83, UXUA_CHRSD ;
DR   Q97JF4, UXUA_CLOAB ;  Q8XP15, UXUA_CLOPE ;  A9KMJ6, UXUA_CLOPH ;
DR   B3R1A0, UXUA_CUPTR ;  A7ZVL9, UXUA_ECO24 ;  B7UQW0, UXUA_ECO27 ;
DR   B7MML2, UXUA_ECO45 ;  B7LDX2, UXUA_ECO55 ;  Q8XEG9, UXUA_ECO57 ;
DR   B5Z3R0, UXUA_ECO5E ;  B7NV92, UXUA_ECO7I ;  B7MT80, UXUA_ECO81 ;
DR   B7LXN0, UXUA_ECO8A ;  C4ZT10, UXUA_ECOBW ;  A8A847, UXUA_ECOHS ;
DR   A1AJI8, UXUA_ECOK1 ;  Q0T8Y5, UXUA_ECOL5 ;  P0A4R9, UXUA_ECOL6 ;
DR   B1ISA3, UXUA_ECOLC ;  P24215, UXUA_ECOLI ;  B7NGX8, UXUA_ECOLU ;
DR   B6I2K2, UXUA_ECOSE ;  B1LDQ8, UXUA_ECOSM ;  Q1R2J3, UXUA_ECOUT ;
DR   C5BG25, UXUA_EDWI9 ;  A4WCK2, UXUA_ENT38 ;  Q82ZC9, UXUA_ENTFA ;
DR   A7MLL8, UXUA_ENTS8 ;  Q6D882, UXUA_ERWCT ;  B7LQG3, UXUA_ESCF3 ;
DR   A5FC71, UXUA_FLAJ1 ;  Q9ZFL7, UXUA_GEOSE ;  A4IP74, UXUA_GEOTN ;
DR   Q4QPI9, UXUA_HAEI8 ;  A5UB85, UXUA_HAEIE ;  A5UFM4, UXUA_HAEIG ;
DR   P44488, UXUA_HAEIN ;  Q0I586, UXUA_HAES1 ;  B0URI0, UXUA_HAES2 ;
DR   Q03U06, UXUA_LACBA ;  Q9CF50, UXUA_LACLA ;  A2RJK2, UXUA_LACLM ;
DR   Q65V66, UXUA_MANSM ;  A6VZ12, UXUA_MARMS ;  Q2RLC8, UXUA_MOOTA ;
DR   Q8EL21, UXUA_OCEIH ;  C6DAZ5, UXUA_PECCP ;  Q7N9Y1, UXUA_PHOLL ;
DR   Q6LG56, UXUA_PHOPR ;  Q6A5D2, UXUA_PROAC ;  A1SR92, UXUA_PSYIN ;
DR   Q987X5, UXUA_RHILO ;  Q92WB5, UXUA_RHIME ;  Q21L94, UXUA_SACD2 ;
DR   B5F621, UXUA_SALA4 ;  A9MQM1, UXUA_SALAR ;  Q57JY0, UXUA_SALCH ;
DR   B5FUZ9, UXUA_SALDC ;  B5QYB0, UXUA_SALEP ;  B5RE94, UXUA_SALG2 ;
DR   B4THM6, UXUA_SALHS ;  B4T5P6, UXUA_SALNS ;  Q5PMP2, UXUA_SALPA ;
DR   A9N4U5, UXUA_SALPB ;  C0PYB4, UXUA_SALPC ;  B5BFU8, UXUA_SALPK ;
DR   B4TVB1, UXUA_SALSV ;  P0A2M8, UXUA_SALTI ;  P0A2M7, UXUA_SALTY ;
DR   A8GGU6, UXUA_SERP5 ;  B2TYW4, UXUA_SHIB3 ;  Q31T20, UXUA_SHIBS ;
DR   Q0SXM7, UXUA_SHIF8 ;  P0A4S0, UXUA_SHIFL ;  Q3YU59, UXUA_SHISS ;
DR   A9EVN4, UXUA_SORC5 ;  Q4L321, UXUA_STAHJ ;  Q3K203, UXUA_STRA1 ;
DR   Q8E6A2, UXUA_STRA3 ;  Q8E0M8, UXUA_STRA5 ;  B4U238, UXUA_STREM ;
DR   C1CAV6, UXUA_STRP7 ;  A4W1U2, UXUA_STRS2 ;  A4VVI4, UXUA_STRSY ;
DR   B9DSL8, UXUA_STRU0 ;  Q9WXS4, UXUA_THEMA ;  Q60040, UXUA_THENE ;
DR   B9K767, UXUA_THENN ;  A5IL01, UXUA_THEP1 ;  B1LA82, UXUA_THESQ ;
DR   C4LCH1, UXUA_TOLAT ;  B1GZ70, UXUA_UNCTG ;  Q87FH9, UXUA_VIBPA ;
DR   Q8D562, UXUA_VIBVU ;  Q7MBZ9, UXUA_VIBVY ;  A1JLS2, UXUA_YERE8 ;
DR   A7FK86, UXUA_YERP3 ;  Q1C9A6, UXUA_YERPA ;  B2K9G8, UXUA_YERPB ;
DR   Q8ZGK8, UXUA_YERPE ;  A9R4P9, UXUA_YERPG ;  Q1CG57, UXUA_YERPN ;
DR   A4TNC6, UXUA_YERPP ;  Q66CT7, UXUA_YERPS ;  B1JS28, UXUA_YERPY ;
//
ID   4.2.1.9
DE   Dihydroxy-acid dehydratase.
CA   2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H(2)O.
PR   PROSITE; PDOC00690;
DR   Q10318, ILV3_SCHPO ;  P39522, ILV3_YEAST ;  Q6FCR9, ILVD1_ACIAD;
DR   Q5P8J4, ILVD1_AROAE;  Q7WQA2, ILVD1_BORBR;  Q7WC98, ILVD1_BORPA;
DR   Q7W069, ILVD1_BORPE;  Q89LK8, ILVD1_BRAJA;  Q394V3, ILVD1_BURS3;
DR   Q8FPX6, ILVD1_COREF;  Q475B2, ILVD1_CUPPJ;  Q8TPV2, ILVD1_METAC;
DR   Q5Z0M2, ILVD1_NOCFA;  Q3IJH1, ILVD1_PSEHT;  Q98BZ8, ILVD1_RHILO;
DR   Q49Z08, ILVD1_STAS1;  Q6F6Q0, ILVD2_ACIAD;  Q5P6F1, ILVD2_AROAE;
DR   Q7WJP7, ILVD2_BORBR;  Q7W497, ILVD2_BORPA;  Q7VUN6, ILVD2_BORPE;
DR   Q89KY5, ILVD2_BRAJA;  Q39DS9, ILVD2_BURS3;  Q8FMR1, ILVD2_COREF;
DR   Q46YI9, ILVD2_CUPPJ;  Q8TKM8, ILVD2_METAC;  Q5YX61, ILVD2_NOCFA;
DR   Q3ID04, ILVD2_PSEHT;  Q98LB3, ILVD2_RHILO;  Q49UX2, ILVD2_STAS1;
DR   Q5NY71, ILVD3_AROAE;  Q7WFQ5, ILVD3_BORBR;  Q89HA2, ILVD3_BRAJA;
DR   Q5YRV8, ILVD3_NOCFA;  B0CEN4, ILVD_ACAM1 ;  A1TMA7, ILVD_ACIAC ;
DR   B7GUZ8, ILVD_ACIB3 ;  B7I2C2, ILVD_ACIB5 ;  B2I2H6, ILVD_ACIBC ;
DR   Q1ILZ0, ILVD_ACIBL ;  B0VQ11, ILVD_ACIBS ;  A3MAA0, ILVD_ACIBT ;
DR   B0VAE1, ILVD_ACIBY ;  A0LSR8, ILVD_ACIC1 ;  A5FXD0, ILVD_ACICJ ;
DR   A3MYG9, ILVD_ACTP2 ;  B3GZT6, ILVD_ACTP7 ;  B0BS03, ILVD_ACTPJ ;
DR   A6VLE6, ILVD_ACTSZ ;  A0KQS4, ILVD_AERHH ;  Q9YG88, ILVD_AERPE ;
DR   A4SHE9, ILVD_AERS4 ;  B9JDW2, ILVD_AGRRK ;  Q8UE43, ILVD_AGRT5 ;
DR   B9JWU3, ILVD_AGRVS ;  B2UR52, ILVD_AKKM8 ;  B8JAT1, ILVD_ANAD2 ;
DR   Q2IH17, ILVD_ANADE ;  A7HIA1, ILVD_ANADF ;  B4UI29, ILVD_ANASK ;
DR   B9MPM8, ILVD_ANATD ;  O67009, ILVD_AQUAE ;  A8EWJ4, ILVD_ARCB4 ;
DR   O29248, ILVD_ARCFU ;  A0JXZ9, ILVD_ARTS2 ;  A8IES7, ILVD_AZOC5 ;
DR   B6YQV1, ILVD_AZOPC ;  A1K344, ILVD_AZOSB ;  C1DI94, ILVD_AZOVD ;
DR   A7Z5T7, ILVD_BACA2 ;  C3P6S2, ILVD_BACAA ;  C3L6P6, ILVD_BACAC ;
DR   A0RCL3, ILVD_BACAH ;  Q81S26, ILVD_BACAN ;  B7JJG8, ILVD_BACC0 ;
DR   Q9XBI3, ILVD_BACC1 ;  B7IS44, ILVD_BACC2 ;  C1EPL6, ILVD_BACC3 ;
DR   B7HIP0, ILVD_BACC4 ;  B7HMM7, ILVD_BACC7 ;  A7GNQ7, ILVD_BACCN ;
DR   B9IX72, ILVD_BACCQ ;  Q81F26, ILVD_BACCR ;  Q63CV3, ILVD_BACCZ ;
DR   Q5L9I8, ILVD_BACFN ;  Q64PS6, ILVD_BACFR ;  Q9K8E4, ILVD_BACHD ;
DR   Q6HKA0, ILVD_BACHK ;  Q65IB0, ILVD_BACLD ;  A8FEC5, ILVD_BACP2 ;
DR   Q5WEM9, ILVD_BACSK ;  P51785, ILVD_BACSU ;  Q8A608, ILVD_BACTN ;
DR   A6L3E7, ILVD_BACV8 ;  A9VPN7, ILVD_BACWK ;  Q6G543, ILVD_BARHE ;
DR   A9ILS3, ILVD_BART1 ;  B2IJH6, ILVD_BEII9 ;  A1A0T7, ILVD_BIFAA ;
DR   Q8G3H2, ILVD_BIFLO ;  B7GUP9, ILVD_BIFLS ;  Q7VRL8, ILVD_BLOFL ;
DR   Q491Z0, ILVD_BLOPB ;  Q2KZT7, ILVD_BORA1 ;  B2S7Z5, ILVD_BRUA1 ;
DR   Q2YNW9, ILVD_BRUA2 ;  Q57FS2, ILVD_BRUAB ;  A9M6V2, ILVD_BRUC2 ;
DR   C0RGF9, ILVD_BRUMB ;  Q8YEN0, ILVD_BRUME ;  A5VN43, ILVD_BRUO2 ;
DR   B0CIL1, ILVD_BRUSI ;  Q8G353, ILVD_BRUSU ;  B8D8F8, ILVD_BUCA5 ;
DR   P57656, ILVD_BUCAI ;  O51887, ILVD_BUCAP ;  B8D8B5, ILVD_BUCAT ;
DR   P59426, ILVD_BUCBP ;  Q056W3, ILVD_BUCCC ;  Q9RQ56, ILVD_BUCDN ;
DR   Q9RQ48, ILVD_BUCMH ;  Q9RQ52, ILVD_BUCSC ;  A3MLQ5, ILVD_BURM7 ;
DR   A2SAC7, ILVD_BURM9 ;  Q62LG7, ILVD_BURMA ;  A1V5Z0, ILVD_BURMS ;
DR   A3NSI6, ILVD_BURP0 ;  Q3JV12, ILVD_BURP1 ;  A3N6U9, ILVD_BURP6 ;
DR   Q63WB9, ILVD_BURPS ;  Q2T0B6, ILVD_BURTA ;  A4JN03, ILVD_BURVG ;
DR   A4XHR9, ILVD_CALS8 ;  A7GVT2, ILVD_CAMC5 ;  A0RRN7, ILVD_CAMFF ;
DR   A7I439, ILVD_CAMHC ;  A8FJH6, ILVD_CAMJ8 ;  A7H1A6, ILVD_CAMJD ;
DR   Q9PJ98, ILVD_CAMJE ;  A1VX91, ILVD_CAMJJ ;  Q5HXE4, ILVD_CAMJR ;
DR   B9KE56, ILVD_CAMLR ;  Q3AER0, ILVD_CARHZ ;  B8H367, ILVD_CAUCN ;
DR   P55186, ILVD_CAUCR ;  B3PIW6, ILVD_CELJU ;  A9WF68, ILVD_CHLAA ;
DR   B8G762, ILVD_CHLAD ;  Q3APB9, ILVD_CHLCH ;  B3EHP3, ILVD_CHLL2 ;
DR   B3QMA2, ILVD_CHLP8 ;  A1BES8, ILVD_CHLPD ;  B9LM83, ILVD_CHLSY ;
DR   B3QSP3, ILVD_CHLT3 ;  Q8KER4, ILVD_CHLTE ;  Q1QU47, ILVD_CHRSD ;
DR   Q7NYJ7, ILVD_CHRVO ;  A5CPY3, ILVD_CLAM3 ;  B0RIN3, ILVD_CLAMS ;
DR   Q97EE3, ILVD_CLOAB ;  A6LTK6, ILVD_CLOB8 ;  B2UYT6, ILVD_CLOBA ;
DR   B2TIR2, ILVD_CLOBB ;  B8I5A9, ILVD_CLOCE ;  B9E299, ILVD_CLOK1 ;
DR   A5N8V4, ILVD_CLOK5 ;  A0Q0E8, ILVD_CLONN ;  P31959, ILVD_CLOPA ;
DR   A9KT71, ILVD_CLOPH ;  A3DIY3, ILVD_CLOTH ;  Q47UN7, ILVD_COLP3 ;
DR   C3PFW7, ILVD_CORA7 ;  Q6NHN6, ILVD_CORDI ;  A4QDM9, ILVD_CORGB ;
DR   Q8NQZ9, ILVD_CORGL ;  Q4JUN3, ILVD_CORJK ;  C4LJI1, ILVD_CORK4 ;
DR   B1WTN3, ILVD_CYAA5 ;  B7JXB4, ILVD_CYAP8 ;  Q11NN5, ILVD_CYTH3 ;
DR   Q47JC0, ILVD_DECAR ;  Q3Z888, ILVD_DEHE1 ;  A5FR35, ILVD_DEHSB ;
DR   Q3ZXH9, ILVD_DEHSC ;  Q1IYZ8, ILVD_DEIGD ;  Q9RV97, ILVD_DEIRA ;
DR   B8FHH7, ILVD_DESAA ;  C6BUM7, ILVD_DESAD ;  B1I250, ILVD_DESAP ;
DR   Q317H9, ILVD_DESDG ;  B8FU95, ILVD_DESHD ;  C4XT34, ILVD_DESMR ;
DR   A8ZTQ7, ILVD_DESOH ;  Q725Q1, ILVD_DESVH ;  B8DMM1, ILVD_DESVM ;
DR   A1V9E1, ILVD_DESVV ;  A8LKN5, ILVD_DINSH ;  A7ZTX3, ILVD_ECO24 ;
DR   B7UMM8, ILVD_ECO27 ;  B7MGI3, ILVD_ECO45 ;  B7L8B3, ILVD_ECO55 ;
DR   Q8XAV1, ILVD_ECO57 ;  B5YY20, ILVD_ECO5E ;  B7NU26, ILVD_ECO7I ;
DR   B7N266, ILVD_ECO81 ;  B7M5B9, ILVD_ECO8A ;  C4ZZ41, ILVD_ECOBW ;
DR   A8A6M7, ILVD_ECOHS ;  A1AHU3, ILVD_ECOK1 ;  Q0TAU9, ILVD_ECOL5 ;
DR   Q8FBR5, ILVD_ECOL6 ;  B1IWX5, ILVD_ECOLC ;  P05791, ILVD_ECOLI ;
DR   B7NF78, ILVD_ECOLU ;  B6I4A8, ILVD_ECOSE ;  B1LLU6, ILVD_ECOSM ;
DR   Q1R4G6, ILVD_ECOUT ;  C5BBA5, ILVD_EDWI9 ;  A4WG37, ILVD_ENT38 ;
DR   Q6CZC7, ILVD_ERWCT ;  B2VI72, ILVD_ERWT9 ;  B7LU82, ILVD_ESCF3 ;
DR   C4Z566, ILVD_EUBE2 ;  C4ZAW6, ILVD_EUBR3 ;  A6GWT7, ILVD_FLAPJ ;
DR   B0TZC0, ILVD_FRAP2 ;  Q2J4D1, ILVD_FRASC ;  A8L8S7, ILVD_FRASN ;
DR   Q14II4, ILVD_FRAT1 ;  B2SH83, ILVD_FRATM ;  A0Q6R5, ILVD_FRATN ;
DR   Q5NH32, ILVD_FRATT ;  A4IYA1, ILVD_FRATW ;  B5EHV2, ILVD_GEOBB ;
DR   Q5KYA5, ILVD_GEOKA ;  B3E5X8, ILVD_GEOLS ;  Q39W79, ILVD_GEOMG ;
DR   B9M5B4, ILVD_GEOSF ;  Q74BW7, ILVD_GEOSL ;  C6E521, ILVD_GEOSM ;
DR   A5G7V6, ILVD_GEOUR ;  Q7NGK1, ILVD_GLOVI ;  Q5FN26, ILVD_GLUOX ;
DR   Q0BQR6, ILVD_GRABC ;  Q4QMF8, ILVD_HAEI8 ;  A5UDY7, ILVD_HAEIE ;
DR   A5UHP2, ILVD_HAEIG ;  P44851, ILVD_HAEIN ;  B8F506, ILVD_HAEPS ;
DR   Q0I1F1, ILVD_HAES1 ;  B0UW18, ILVD_HAES2 ;  Q2SA20, ILVD_HAHCH ;
DR   A1WTG1, ILVD_HALHL ;  Q5V545, ILVD_HALMA ;  B8CX17, ILVD_HALOH ;
DR   Q7VHW3, ILVD_HELHP ;  A4G341, ILVD_HERAR ;  B4U6Z8, ILVD_HYDS0 ;
DR   Q0C2B5, ILVD_HYPNA ;  A8AB39, ILVD_IGNH4 ;  A6SVP5, ILVD_JANMA ;
DR   B5XZ01, ILVD_KLEP3 ;  A6TGF8, ILVD_KLEP7 ;  B2GLR9, ILVD_KOCRD ;
DR   Q02139, ILVD_LACLA ;  A2RKQ9, ILVD_LACLM ;  Q02YY5, ILVD_LACLS ;
DR   Q6AEN9, ILVD_LEIXX ;  Q04RA5, ILVD_LEPBJ ;  Q053H5, ILVD_LEPBL ;
DR   B1Y816, ILVD_LEPCP ;  Q72TC0, ILVD_LEPIC ;  Q8F219, ILVD_LEPIN ;
DR   Q03UL2, ILVD_LEUMM ;  Q92A32, ILVD_LISIN ;  C1KWS7, ILVD_LISMC ;
DR   Q71Y38, ILVD_LISMF ;  B8DBU8, ILVD_LISMH ;  Q8Y5S2, ILVD_LISMO ;
DR   A0AK88, ILVD_LISW6 ;  B9EBF6, ILVD_MACCJ ;  Q2W485, ILVD_MAGSA ;
DR   A0L8Q3, ILVD_MAGSM ;  Q65QD4, ILVD_MANSM ;  A6W1Q9, ILVD_MARMS ;
DR   A6UUU2, ILVD_META3 ;  A7I7L0, ILVD_METB6 ;  Q46AU2, ILVD_METBF ;
DR   Q12TW7, ILVD_METBU ;  Q606D6, ILVD_METCA ;  Q1H4H6, ILVD_METFK ;
DR   Q2FMZ1, ILVD_METHJ ;  Q58672, ILVD_METJA ;  Q8TW40, ILVD_METKA ;
DR   A4FZM0, ILVD_METM5 ;  A9A6N6, ILVD_METM6 ;  A6VIV7, ILVD_METM7 ;
DR   Q8Q078, ILVD_METMA ;  A3CU68, ILVD_METMJ ;  Q6M0F3, ILVD_METMP ;
DR   A2SFL0, ILVD_METPP ;  A5UML4, ILVD_METS3 ;  A4YEN4, ILVD_METS5 ;
DR   B8EQC8, ILVD_METSB ;  Q2NE10, ILVD_METST ;  O27498, ILVD_METTH ;
DR   A0B6Y9, ILVD_METTP ;  A6URV4, ILVD_METVS ;  B0JJP7, ILVD_MICAN ;
DR   Q2RG93, ILVD_MOOTA ;  A0QMH2, ILVD_MYCA1 ;  P65155, ILVD_MYCBO ;
DR   O06069, ILVD_MYCLE ;  Q73TT7, ILVD_MYCPA ;  A3PSS2, ILVD_MYCSJ ;
DR   P65154, ILVD_MYCTU ;  A0PMV4, ILVD_MYCUA ;  Q3IMV2, ILVD_NATPD ;
DR   B9L6Y0, ILVD_NAUPA ;  Q5F8G6, ILVD_NEIG1 ;  Q9JUE0, ILVD_NEIMA ;
DR   Q9JS61, ILVD_NEIMB ;  A1KU04, ILVD_NEIMF ;  Q0ADX6, ILVD_NITEC ;
DR   Q82XY7, ILVD_NITEU ;  Q1QRS7, ILVD_NITHX ;  Q2YC67, ILVD_NITMU ;
DR   Q3J9N3, ILVD_NITOC ;  A6Q182, ILVD_NITSB ;  Q3SW60, ILVD_NITWN ;
DR   A1SM84, ILVD_NOCSJ ;  B2J456, ILVD_NOSP7 ;  Q8YTE6, ILVD_NOSS1 ;
DR   Q2G7E9, ILVD_NOVAD ;  Q8EN63, ILVD_OCEIH ;  A6WV39, ILVD_OCHA4 ;
DR   A6LDP0, ILVD_PARD8 ;  A1B673, ILVD_PARDP ;  A7HXI4, ILVD_PARL1 ;
DR   P57957, ILVD_PASMU ;  C6DHH1, ILVD_PECCP ;  Q3A3A5, ILVD_PELCD ;
DR   Q3B589, ILVD_PELLD ;  B4SDK2, ILVD_PELPB ;  A1AS43, ILVD_PELPD ;
DR   Q4FM19, ILVD_PELUB ;  C0QUI2, ILVD_PERMH ;  Q7MYJ5, ILVD_PHOLL ;
DR   Q6LLH7, ILVD_PHOPR ;  Q6KZ30, ILVD_PICTO ;  A1VR98, ILVD_POLNA ;
DR   B1XVE9, ILVD_POLNS ;  Q12BW0, ILVD_POLSJ ;  A4SWN4, ILVD_POLSQ ;
DR   A3PCI2, ILVD_PROM0 ;  A8G4F2, ILVD_PROM2 ;  A2CAC6, ILVD_PROM3 ;
DR   A9BAQ7, ILVD_PROM4 ;  A2BW57, ILVD_PROM5 ;  Q31BA3, ILVD_PROM9 ;
DR   Q7VC95, ILVD_PROMA ;  B4F1U3, ILVD_PROMH ;  Q7TV16, ILVD_PROMM ;
DR   Q7V1T1, ILVD_PROMP ;  A2BQQ9, ILVD_PROMS ;  Q46LF6, ILVD_PROMT ;
DR   A4SFC2, ILVD_PROVI ;  Q48PA6, ILVD_PSE14 ;  Q15MY9, ILVD_PSEA6 ;
DR   A6UYF6, ILVD_PSEA7 ;  B7V2R6, ILVD_PSEA8 ;  Q02U62, ILVD_PSEAB ;
DR   Q9I6E0, ILVD_PSEAE ;  Q1IGF7, ILVD_PSEE4 ;  Q4K498, ILVD_PSEF5 ;
DR   C3K3P0, ILVD_PSEFS ;  A4Y036, ILVD_PSEMY ;  A5WAG2, ILVD_PSEP1 ;
DR   Q3K559, ILVD_PSEPF ;  B0KN82, ILVD_PSEPG ;  Q88CQ2, ILVD_PSEPK ;
DR   B1J2M0, ILVD_PSEPW ;  Q87V83, ILVD_PSESM ;  Q4ZZ83, ILVD_PSEU2 ;
DR   A4VRN4, ILVD_PSEU5 ;  Q4FS54, ILVD_PSYA2 ;  A1SRU7, ILVD_PSYIN ;
DR   Q9UZ03, ILVD_PYRAB ;  Q8ZYU6, ILVD_PYRAE ;  A4WN46, ILVD_PYRAR ;
DR   A3MUK8, ILVD_PYRCJ ;  Q8U297, ILVD_PYRFU ;  A1RSI5, ILVD_PYRIL ;
DR   Q8XWR1, ILVD_RALSO ;  A9WP05, ILVD_RENSM ;  B3PWV1, ILVD_RHIE6 ;
DR   Q2K9I7, ILVD_RHIEC ;  Q1MIB2, ILVD_RHIL3 ;  B5ZZ62, ILVD_RHILW ;
DR   Q92M28, ILVD_RHIME ;  C3MIR3, ILVD_RHISN ;  Q7UJ69, ILVD_RHOBA ;
DR   P31874, ILVD_RHOCA ;  Q21X56, ILVD_RHOFD ;  Q2ISQ1, ILVD_RHOP2 ;
DR   Q07IE7, ILVD_RHOP5 ;  Q6N9S5, ILVD_RHOPA ;  B3Q6A0, ILVD_RHOPT ;
DR   Q2RTF9, ILVD_RHORT ;  A3PRB5, ILVD_RHOS1 ;  Q3IXP4, ILVD_RHOS4 ;
DR   A7NNA3, ILVD_ROSCS ;  A5UY13, ILVD_ROSS1 ;  A1AWH6, ILVD_RUTMC ;
DR   Q21NV7, ILVD_SACD2 ;  B5EZ28, ILVD_SALA4 ;  A8M5F5, ILVD_SALAI ;
DR   Q57HU7, ILVD_SALCH ;  B5FN65, ILVD_SALDC ;  B5QVG2, ILVD_SALEP ;
DR   B5RFT3, ILVD_SALG2 ;  B4TB04, ILVD_SALHS ;  B4SZ17, ILVD_SALNS ;
DR   Q5PK00, ILVD_SALPA ;  A9MXE2, ILVD_SALPB ;  C0Q2U8, ILVD_SALPC ;
DR   B5BIR7, ILVD_SALPK ;  B4TNS1, ILVD_SALSV ;  Q8Z377, ILVD_SALTI ;
DR   P40810, ILVD_SALTY ;  A8GL60, ILVD_SERP5 ;  A1SAS5, ILVD_SHEAM ;
DR   B8E8A9, ILVD_SHEB2 ;  A3D9T2, ILVD_SHEB5 ;  A6WTI9, ILVD_SHEB8 ;
DR   A9L621, ILVD_SHEB9 ;  Q12IN9, ILVD_SHEDO ;  Q088M9, ILVD_SHEFN ;
DR   B0TJR3, ILVD_SHEHH ;  A3Q9L6, ILVD_SHELP ;  Q8E9D9, ILVD_SHEON ;
DR   A8GZD9, ILVD_SHEPA ;  A4YBI7, ILVD_SHEPC ;  B8CHS0, ILVD_SHEPW ;
DR   A0KS32, ILVD_SHESA ;  A8G0Z3, ILVD_SHESH ;  Q0HNC3, ILVD_SHESM ;
DR   Q0HQG3, ILVD_SHESR ;  A1RPG2, ILVD_SHESW ;  B1KQ88, ILVD_SHEWM ;
DR   B2TU20, ILVD_SHIB3 ;  Q31UL3, ILVD_SHIBS ;  Q329V0, ILVD_SHIDS ;
DR   Q0SYW3, ILVD_SHIF8 ;  Q83PI6, ILVD_SHIFL ;  Q3YVJ3, ILVD_SHISS ;
DR   Q5LN98, ILVD_SILPO ;  Q1GDP8, ILVD_SILST ;  A6UD23, ILVD_SINMW ;
DR   Q2NQA6, ILVD_SODGM ;  Q1GTW7, ILVD_SPHAL ;  A7X4M5, ILVD_STAA1 ;
DR   A6U3D8, ILVD_STAA2 ;  Q2FF71, ILVD_STAA3 ;  Q2FWK7, ILVD_STAA8 ;
DR   A5IUJ9, ILVD_STAA9 ;  Q2YUF6, ILVD_STAAB ;  Q5HEE8, ILVD_STAAC ;
DR   A6QIQ0, ILVD_STAAE ;  P65156, ILVD_STAAM ;  P65157, ILVD_STAAN ;
DR   Q6GF19, ILVD_STAAR ;  Q6G7Q4, ILVD_STAAS ;  A8Z4V6, ILVD_STAAT ;
DR   P65158, ILVD_STAAW ;  B9DMJ2, ILVD_STACT ;  Q5HMG3, ILVD_STAEQ ;
DR   Q8CNL6, ILVD_STAES ;  Q4L7T6, ILVD_STAHJ ;  Q82E99, ILVD_STRAW ;
DR   O69198, ILVD_STRCO ;  B1VSL0, ILVD_STRGG ;  B4SMU1, ILVD_STRM5 ;
DR   B2FMH4, ILVD_STRMK ;  Q8DRT7, ILVD_STRMU ;  Q04I44, ILVD_STRP2 ;
DR   B5E3D3, ILVD_STRP4 ;  C1CAX1, ILVD_STRP7 ;  B1I9U2, ILVD_STRPI ;
DR   B8ZPQ2, ILVD_STRPJ ;  P65159, ILVD_STRPN ;  B2IN52, ILVD_STRPS ;
DR   P65160, ILVD_STRR6 ;  A4W3W3, ILVD_STRS2 ;  A3CR42, ILVD_STRSV ;
DR   A4VXL9, ILVD_STRSY ;  Q5LYH1, ILVD_STRT1 ;  Q5M334, ILVD_STRT2 ;
DR   C1CH59, ILVD_STRZJ ;  C1CNA5, ILVD_STRZP ;  C1CU32, ILVD_STRZT ;
DR   Q4J860, ILVD_SULAC ;  Q30UI5, ILVD_SULDN ;  C3N1G8, ILVD_SULIA ;
DR   C4KKJ8, ILVD_SULIK ;  C3MKM4, ILVD_SULIL ;  C3MS47, ILVD_SULIM ;
DR   C3NLR8, ILVD_SULIN ;  C3N9R7, ILVD_SULIY ;  A6QD02, ILVD_SULNB ;
DR   Q97UB2, ILVD_SULSO ;  B2VAB3, ILVD_SULSY ;  Q96YK0, ILVD_SULTO ;
DR   Q67KX6, ILVD_SYMTH ;  Q2LXP6, ILVD_SYNAS ;  Q31QL1, ILVD_SYNE7 ;
DR   A0LF54, ILVD_SYNFM ;  Q2JTX6, ILVD_SYNJA ;  Q2JK60, ILVD_SYNJB ;
DR   Q5N3N2, ILVD_SYNP6 ;  Q7U763, ILVD_SYNPX ;  A5GTE2, ILVD_SYNR3 ;
DR   Q3AXL0, ILVD_SYNS9 ;  Q3AK67, ILVD_SYNSC ;  P74689, ILVD_SYNY3 ;
DR   C5BMB1, ILVD_TERTT ;  Q8DK13, ILVD_THEEB ;  Q47MS7, ILVD_THEFY ;
DR   Q9WZ21, ILVD_THEMA ;  B1YBN8, ILVD_THENV ;  A5IJM4, ILVD_THEP1 ;
DR   B1L8U4, ILVD_THESQ ;  Q72JA8, ILVD_THET2 ;  Q5SIY0, ILVD_THET8 ;
DR   Q8RDJ9, ILVD_THETN ;  B5YKD5, ILVD_THEYD ;  Q31I28, ILVD_THICR ;
DR   C4LDS1, ILVD_TOLAT ;  Q8KTS9, ILVD_TREPR ;  Q11AD1, ILVD_TRIEI ;
DR   Q83HI6, ILVD_TROW8 ;  Q83GP9, ILVD_TROWT ;  B1GYS7, ILVD_UNCTG ;
DR   A1WMU5, ILVD_VEREI ;  A5CWQ3, ILVD_VESOH ;  A5F497, ILVD_VIBC3 ;
DR   Q9KVW0, ILVD_VIBCH ;  C3LPA1, ILVD_VIBCM ;  Q5E1P2, ILVD_VIBF1 ;
DR   B5FCY6, ILVD_VIBFM ;  Q87KB6, ILVD_VIBPA ;  B7VMZ0, ILVD_VIBSL ;
DR   Q8DDG1, ILVD_VIBVU ;  Q7MGI8, ILVD_VIBVY ;  Q7MAN4, ILVD_WOLSU ;
DR   Q8PQI0, ILVD_XANAC ;  Q3BYS5, ILVD_XANC5 ;  Q4UZT2, ILVD_XANC8 ;
DR   B0RMB4, ILVD_XANCB ;  Q8PDJ3, ILVD_XANCP ;  Q2NY76, ILVD_XANOM ;
DR   B2SK80, ILVD_XANOP ;  Q5GUY8, ILVD_XANOR ;  A7IBD6, ILVD_XANP2 ;
DR   B2I699, ILVD_XYLF2 ;  Q9PH47, ILVD_XYLFA ;  B0U281, ILVD_XYLFM ;
DR   Q87F63, ILVD_XYLFT ;  A1JI53, ILVD_YERE8 ;  A7FD26, ILVD_YERP3 ;
DR   Q1CBS9, ILVD_YERPA ;  B2JZH0, ILVD_YERPB ;  Q8ZAB3, ILVD_YERPE ;
DR   A9R8F3, ILVD_YERPG ;  Q1CNM8, ILVD_YERPN ;  A4TRE8, ILVD_YERPP ;
DR   Q66G45, ILVD_YERPS ;  B1JQ32, ILVD_YERPY ;  Q5NLJ4, ILVD_ZYMMO ;
//
ID   4.2.1.10
DE   3-dehydroquinate dehydratase.
CA   3-dehydroquinate = 3-dehydroshikimate + H(2)O.
PR   PROSITE; PDOC00788;
PR   PROSITE; PDOC00789;
DR   B0XQT1, 3DHQ1_ASPFC;  B8NIM4, 3DHQ1_ASPFN;  Q6MYX3, 3DHQ1_ASPFU;
DR   Q0D131, 3DHQ1_ASPTN;  C7ZKL6, 3DHQ1_NECH7;  A1D2R0, 3DHQ1_NEOFI;
DR   B0XZU3, 3DHQ2_ASPFC;  B8NXI4, 3DHQ2_ASPFN;  Q4WZ01, 3DHQ2_ASPFU;
DR   P0CI63, 3DHQ2_ASPTN;  C7Z622, 3DHQ2_NECH7;  A1D5T7, 3DHQ2_NEOFI;
DR   Q59087, 3DHQ_ACIAD ;  A1CPW7, 3DHQ_ASPCL ;  Q2U2Z2, 3DHQ_ASPOR ;
DR   A6S694, 3DHQ_BOTFB ;  Q59Z17, 3DHQ_CANAL ;  B9WC12, 3DHQ_CANDC ;
DR   C5M799, 3DHQ_CANTT ;  C4YCH0, 3DHQ_CLAL4 ;  Q6BKA3, 3DHQ_DEBHA ;
DR   P05147, 3DHQ_EMENI ;  A4QYU7, 3DHQ_MAGO7 ;  Q58HK4, 3DHQ_NEUAF ;
DR   P05195, 3DHQ_NEUCR ;  B6H4C6, 3DHQ_PENCW ;  B6Q3C6, 3DHQ_PENMQ ;
DR   Q0U9X3, 3DHQ_PHANO ;  A5DAY6, 3DHQ_PICGU ;  A3LYE4, 3DHQ_PICST ;
DR   Q86ZM3, 3DHQ_PODAN ;  B2WGR9, 3DHQ_PYRTR ;  A7F996, 3DHQ_SCLS1 ;
DR   D1ZR99, 3DHQ_SORMK ;  P0CI61, 3DHQ_TALSN ;  Q4PIL0, 3DHQ_USTMA ;
DR   C9SU87, 3DHQ_VERA1 ;  A5H2Q8, ARO11_LODEL;  B6QWH9, ARO11_PENMQ;
DR   A5H2P4, ARO12_LODEL;  B6QCA7, ARO12_PENMQ;  C0NL63, ARO1_AJECG ;
DR   C6HCG7, ARO1_AJECH ;  A6R8Q8, ARO1_AJECN ;  C5G8R4, ARO1_AJEDR ;
DR   C5JKE6, ARO1_AJEDS ;  C5FQ73, ARO1_ARTOC ;  Q74ZZ1, ARO1_ASHGO ;
DR   A1CP85, ARO1_ASPCL ;  B0XRM8, ARO1_ASPFC ;  B8N4Q9, ARO1_ASPFN ;
DR   Q4WS76, ARO1_ASPFU ;  Q2UCP6, ARO1_ASPOR ;  Q0D0F3, ARO1_ASPTN ;
DR   Q5AME2, ARO1_CANAL ;  B9WFG1, ARO1_CANDC ;  Q6FIV4, ARO1_CANGA ;
DR   C5M1X2, ARO1_CANTT ;  C4Y9D5, ARO1_CLAL4 ;  C5PA86, ARO1_COCP7 ;
DR   A8NMB4, ARO1_COPC7 ;  P0CM23, ARO1_CRYNB ;  P0CM22, ARO1_CRYNJ ;
DR   P07547, ARO1_EMENI ;  Q6CJC4, ARO1_KLULA ;  B0D6H2, ARO1_LACBS ;
DR   C5DN02, ARO1_LACTC ;  A4RD09, ARO1_MAGO7 ;  A8QCB2, ARO1_MALGO ;
DR   C7YZ74, ARO1_NECH7 ;  A1D244, ARO1_NEOFI ;  Q8X071, ARO1_NEUCR ;
DR   C1H8L1, ARO1_PARBA ;  C1FYJ9, ARO1_PARBD ;  C0S433, ARO1_PARBP ;
DR   B6HAA7, ARO1_PENCW ;  Q0V3H0, ARO1_PHANO ;  C4R4R8, ARO1_PICPG ;
DR   A3LSZ2, ARO1_PICST ;  Q12659, ARO1_PNECA ;  B2B223, ARO1_PODAN ;
DR   B6JVD0, ARO1_SCHJY ;  Q9P7R0, ARO1_SCHPO ;  A7F7H0, ARO1_SCLS1 ;
DR   Q5XNP0, ARO1_SCLSC ;  D1ZA70, ARO1_SORMK ;  B8M0U4, ARO1_TALSN ;
DR   Q8J294, ARO1_THACU ;  C4JYG6, ARO1_UNCRE ;  Q4P8F6, ARO1_USTMA ;
DR   C9SE96, ARO1_VERA1 ;  Q6C1X5, ARO1_YARLI ;  B3LGE9, ARO1_YEAS1 ;
DR   C7GIN5, ARO1_YEAS2 ;  A6ZY89, ARO1_YEAS7 ;  C8Z543, ARO1_YEAS8 ;
DR   P08566, ARO1_YEAST ;  C5DVG6, ARO1_ZYGRC ;  P56961, ARODE_CHLMU;
DR   Q9Z6M4, ARODE_CHLPN;  O84375, ARODE_CHLTR;  Q9YEK1, AROD_AERPE ;
DR   A8MJ87, AROD_ALKOO ;  O66440, AROD_AQUAE ;  O30011, AROD_ARCFU ;
DR   Q5P8W0, AROD_AROAE ;  A7Z2G6, AROD_BACA2 ;  Q65M66, AROD_BACLD ;
DR   Q5WKM9, AROD_BACSK ;  P35146, AROD_BACSU ;  B2TQ57, AROD_CLOBB ;
DR   Q186A6, AROD_CLOD6 ;  B9E0D7, AROD_CLOK1 ;  A5N6W8, AROD_CLOK5 ;
DR   A0PYE7, AROD_CLONN ;  B6J6K1, AROD_COXB1 ;  B6J3T7, AROD_COXB2 ;
DR   A9KDC5, AROD_COXBN ;  A9N909, AROD_COXBR ;  Q83A36, AROD_COXBU ;
DR   Q3Z989, AROD_DEHE1 ;  A5FRZ6, AROD_DEHSB ;  Q3ZZN2, AROD_DEHSC ;
DR   Q6AIT8, AROD_DESPS ;  A7ZMF8, AROD_ECO24 ;  B7US32, AROD_ECO27 ;
DR   B7MAQ3, AROD_ECO45 ;  B7L5P5, AROD_ECO55 ;  Q8X5X7, AROD_ECO57 ;
DR   B5YPY0, AROD_ECO5E ;  B7NTU3, AROD_ECO7I ;  B7MVG9, AROD_ECO81 ;
DR   B7M0P9, AROD_ECO8A ;  C4ZYF5, AROD_ECOBW ;  B1XG01, AROD_ECODH ;
DR   A8A0N9, AROD_ECOHS ;  A1ABN0, AROD_ECOK1 ;  Q0THD6, AROD_ECOL5 ;
DR   Q8FH42, AROD_ECOL6 ;  B1IQ63, AROD_ECOLC ;  P05194, AROD_ECOLI ;
DR   B7N529, AROD_ECOLU ;  B6IBD3, AROD_ECOSE ;  B1LE43, AROD_ECOSM ;
DR   Q1RBA3, AROD_ECOUT ;  P36923, AROD_ENTFA ;  Q5KY94, AROD_GEOKA ;
DR   C5D2V7, AROD_GEOSW ;  A4IPP2, AROD_GEOTN ;  Q5V145, AROD_HALMA ;
DR   B0R338, AROD_HALS3 ;  Q9HSB4, AROD_HALSA ;  Q18DY7, AROD_HALWD ;
DR   B4U701, AROD_HYDS0 ;  A8A962, AROD_IGNH4 ;  B5Y1W9, AROD_KLEP3 ;
DR   A6T4L2, AROD_KLEP7 ;  Q9CF39, AROD_LACLA ;  A2RJD1, AROD_LACLM ;
DR   Q02XM4, AROD_LACLS ;  Q88SD8, AROD_LACPL ;  Q38X91, AROD_LACSS ;
DR   Q92EG6, AROD_LISIN ;  C1L005, AROD_LISMC ;  Q723F8, AROD_LISMF ;
DR   B8DCI1, AROD_LISMH ;  Q8Y9N4, AROD_LISMO ;  A0AFU8, AROD_LISW6 ;
DR   A6UTA2, AROD_META3 ;  Q8THC4, AROD_METAC ;  A7I8M6, AROD_METB6 ;
DR   Q46DZ7, AROD_METBF ;  Q12UJ8, AROD_METBU ;  Q2FQV3, AROD_METHJ ;
DR   Q58849, AROD_METJA ;  Q8TY76, AROD_METKA ;  A4FWC6, AROD_METM5 ;
DR   A9A9R9, AROD_METM6 ;  A6VGY0, AROD_METM7 ;  Q8PXE7, AROD_METMA ;
DR   A3CV25, AROD_METMJ ;  Q6LXF7, AROD_METMP ;  A5UJQ8, AROD_METS3 ;
DR   A4YHV8, AROD_METS5 ;  Q2NGS8, AROD_METST ;  O26666, AROD_METTH ;
DR   A0B6K7, AROD_METTP ;  A6UQ39, AROD_METVS ;  Q5F8N0, AROD_NEIG1 ;
DR   B4RLX9, AROD_NEIG2 ;  Q9JTR9, AROD_NEIMA ;  Q9JYT0, AROD_NEIMB ;
DR   A1KUQ1, AROD_NEIMF ;  Q3A2I0, AROD_PELCD ;  Q9V1H8, AROD_PYRAB ;
DR   Q8ZW59, AROD_PYRAE ;  Q8U0A7, AROD_PYRFU ;  Q5JFV1, AROD_PYRKO ;
DR   Q21VV5, AROD_RHOFD ;  B5F7D7, AROD_SALA4 ;  Q57PS8, AROD_SALCH ;
DR   B5FJ82, AROD_SALDC ;  Q9RN77, AROD_SALEN ;  B5QVU3, AROD_SALEP ;
DR   B5RAU8, AROD_SALG2 ;  B4TGJ6, AROD_SALHS ;  Q5PH79, AROD_SALPA ;
DR   A9N159, AROD_SALPB ;  B4TUS2, AROD_SALSV ;  P24670, AROD_SALTI ;
DR   P58687, AROD_SALTY ;  B2U2J7, AROD_SHIB3 ;  Q321F0, AROD_SHIBS ;
DR   Q32GE2, AROD_SHIDS ;  O87007, AROD_SHIDY ;  Q0T478, AROD_SHIF8 ;
DR   Q83RA1, AROD_SHIFL ;  Q3Z247, AROD_SHISS ;  A7X013, AROD_STAA1 ;
DR   A6TZT3, AROD_STAA2 ;  Q2FIJ1, AROD_STAA3 ;  Q2G002, AROD_STAA8 ;
DR   A5IR07, AROD_STAA9 ;  Q2YWJ9, AROD_STAAB ;  Q5HHL2, AROD_STAAC ;
DR   A6QFB2, AROD_STAAE ;  P63586, AROD_STAAM ;  P63587, AROD_STAAN ;
DR   Q6GII7, AROD_STAAR ;  Q6GB27, AROD_STAAS ;  A8Z1D4, AROD_STAAT ;
DR   Q8NXI0, AROD_STAAW ;  B9DJG9, AROD_STACT ;  Q5HQR7, AROD_STAEQ ;
DR   Q8CPX1, AROD_STAES ;  Q4L4R1, AROD_STAHJ ;  Q49W41, AROD_STAS1 ;
DR   Q3K0D3, AROD_STRA1 ;  Q8E4F2, AROD_STRA3 ;  Q8DYU4, AROD_STRA5 ;
DR   C0M8T8, AROD_STRE4 ;  B4U2K6, AROD_STREM ;  A8AXZ6, AROD_STRGC ;
DR   Q8DUW4, AROD_STRMU ;  P63590, AROD_STRP1 ;  Q04JX0, AROD_STRP2 ;
DR   P0CZ74, AROD_STRP3 ;  B5E5N5, AROD_STRP4 ;  Q5XCT7, AROD_STRP6 ;
DR   C1C7X8, AROD_STRP7 ;  P63592, AROD_STRP8 ;  Q1JCG7, AROD_STRPB ;
DR   Q1JME5, AROD_STRPC ;  Q1JHJ2, AROD_STRPD ;  Q1J7B3, AROD_STRPF ;
DR   A2RF79, AROD_STRPG ;  B1ICH8, AROD_STRPI ;  B8ZKM6, AROD_STRPJ ;
DR   Q48U89, AROD_STRPM ;  P63588, AROD_STRPN ;  P0CZ75, AROD_STRPQ ;
DR   B2IQJ5, AROD_STRPS ;  B5XKU3, AROD_STRPZ ;  P63589, AROD_STRR6 ;
DR   A4W247, AROD_STRS2 ;  C0MGL4, AROD_STRS7 ;  A3CNV9, AROD_STRSV ;
DR   A4VVU0, AROD_STRSY ;  Q5M0M2, AROD_STRT1 ;  Q5M558, AROD_STRT2 ;
DR   Q03LH6, AROD_STRTD ;  C1CEW6, AROD_STRZJ ;  C1CL86, AROD_STRZP ;
DR   C1CQX8, AROD_STRZT ;  Q4JC71, AROD_SULAC ;  Q980I4, AROD_SULSO ;
DR   Q96Y90, AROD_SULTO ;  A0LLU8, AROD_SYNFM ;  Q9HLV9, AROD_THEAC ;
DR   C5A786, AROD_THEGJ ;  B6YX10, AROD_THEON ;  Q97CA8, AROD_THEVO ;
DR   B5YH80, AROD_THEYD ;  Q0W4B8, AROD_UNCMA ;  Q8UFR5, AROQ1_AGRT5;
DR   Q89MA1, AROQ1_BRAJA;  Q8FSF1, AROQ1_COREF;  O30557, AROQ1_PSEAE;
DR   Q88QD4, AROQ1_PSEPK;  Q8XVP5, AROQ1_RALSO;  Q8U7B8, AROQ2_AGRT5;
DR   Q89GF9, AROQ2_BRAJA;  Q8FT32, AROQ2_COREF;  Q9I6P3, AROQ2_PSEAE;
DR   Q88K84, AROQ2_PSEPK;  Q8XQ89, AROQ2_RALSO;  B0CEJ4, AROQ_ACAM1 ;
DR   Q6FBI3, AROQ_ACIAD ;  B7H1C7, AROQ_ACIB3 ;  B7I9Y9, AROQ_ACIB5 ;
DR   B2I3H4, AROQ_ACIBC ;  B0VR94, AROQ_ACIBS ;  A3M692, AROQ_ACIBT ;
DR   B0V732, AROQ_ACIBY ;  B9MAV8, AROQ_ACIET ;  A1W6C8, AROQ_ACISJ ;
DR   A3N3F8, AROQ_ACTP2 ;  B3GZB8, AROQ_ACTP7 ;  B0BTE1, AROQ_ACTPJ ;
DR   P43877, AROQ_ACTPL ;  A0KNI3, AROQ_AERHH ;  A4SJM5, AROQ_AERS4 ;
DR   Q0ACQ4, AROQ_ALHEH ;  B6ENA0, AROQ_ALISL ;  P46380, AROQ_AMYME ;
DR   B9MKD4, AROQ_ANATD ;  B7GHE3, AROQ_ANOFW ;  A8ES39, AROQ_ARCB4 ;
DR   A8IBI0, AROQ_AZOC5 ;  C3P7X7, AROQ_BACAA ;  C3LKM7, AROQ_BACAC ;
DR   Q81M32, AROQ_BACAN ;  B7JM50, AROQ_BACC0 ;  Q730Z4, AROQ_BACC1 ;
DR   B7IXJ0, AROQ_BACC2 ;  C1ERS1, AROQ_BACC3 ;  B7HB70, AROQ_BACC4 ;
DR   B7HNW2, AROQ_BACC7 ;  A7GSL7, AROQ_BACCN ;  B9IXJ3, AROQ_BACCQ ;
DR   Q818P8, AROQ_BACCR ;  Q634Y5, AROQ_BACCZ ;  Q9K949, AROQ_BACHD ;
DR   Q6HDW6, AROQ_BACHK ;  Q65HH2, AROQ_BACLD ;  A8FF31, AROQ_BACP2 ;
DR   P54517, AROQ_BACSU ;  A9VGY2, AROQ_BACWK ;  A1UU72, AROQ_BARBK ;
DR   Q6G523, AROQ_BARHE ;  A9IM00, AROQ_BART1 ;  Q7VRC5, AROQ_BLOFL ;
DR   Q493B0, AROQ_BLOPB ;  Q2KUV4, AROQ_BORA1 ;  Q7WF89, AROQ_BORBR ;
DR   Q7W3V9, AROQ_BORPA ;  A9I1W8, AROQ_BORPD ;  Q7VUS7, AROQ_BORPE ;
DR   A5EJC6, AROQ_BRASB ;  B2S5E0, AROQ_BRUA1 ;  Q2YNP1, AROQ_BRUA2 ;
DR   P0C101, AROQ_BRUAB ;  A9MAS9, AROQ_BRUC2 ;  C0RIP1, AROQ_BRUMB ;
DR   Q8YGU6, AROQ_BRUME ;  B0CLN2, AROQ_BRUSI ;  Q8G120, AROQ_BRUSU ;
DR   B8D9I2, AROQ_BUCA5 ;  P57479, AROQ_BUCAI ;  Q8K9F1, AROQ_BUCAP ;
DR   B8D7T4, AROQ_BUCAT ;  Q89AE0, AROQ_BUCBP ;  Q057I1, AROQ_BUCCC ;
DR   A4XLN1, AROQ_CALS8 ;  A7I2M4, AROQ_CAMHC ;  A8FJM2, AROQ_CAMJ8 ;
DR   A7H1F1, AROQ_CAMJD ;  Q9PJ53, AROQ_CAMJE ;  A1VXF1, AROQ_CAMJJ ;
DR   Q5HX97, AROQ_CAMJR ;  B9KEV8, AROQ_CAMLR ;  Q3AAZ0, AROQ_CARHZ ;
DR   B8GWN2, AROQ_CAUCN ;  Q9A744, AROQ_CAUCR ;  B0SXA8, AROQ_CAUSK ;
DR   B3PBH2, AROQ_CELJU ;  Q8KD64, AROQ_CHLTE ;  Q7NZD5, AROQ_CHRVO ;
DR   A8AQF2, AROQ_CITK8 ;  Q97KL8, AROQ_CLOAB ;  A7FUV3, AROQ_CLOB1 ;
DR   C3KXD9, AROQ_CLOB6 ;  A6M249, AROQ_CLOB8 ;  A5I322, AROQ_CLOBH ;
DR   C1FPC5, AROQ_CLOBJ ;  B1IMQ1, AROQ_CLOBK ;  A7GEL0, AROQ_CLOBL ;
DR   B1KT66, AROQ_CLOBM ;  Q0TT93, AROQ_CLOP1 ;  Q8XMI6, AROQ_CLOPE ;
DR   A9KMD8, AROQ_CLOPH ;  Q0SV29, AROQ_CLOPS ;  Q487R8, AROQ_COLP3 ;
DR   Q6NH05, AROQ_CORDI ;  A4QB64, AROQ_CORGB ;  O52377, AROQ_CORGL ;
DR   P96750, AROQ_CORP2 ;  B7KFE6, AROQ_CYAP7 ;  Q9RW91, AROQ_DEIRA ;
DR   B1I3B8, AROQ_DESAP ;  B8FQ77, AROQ_DESHD ;  Q24UX5, AROQ_DESHY ;
DR   A4J3D2, AROQ_DESRM ;  B8E0Z3, AROQ_DICTD ;  A8LKS9, AROQ_DINSH ;
DR   C5BEW3, AROQ_EDWI9 ;  A4WF69, AROQ_ENT38 ;  Q6DAJ1, AROQ_ERWCT ;
DR   B2VGX5, AROQ_ERWT9 ;  C4Z158, AROQ_EUBE2 ;  C4L3G2, AROQ_EXISA ;
DR   B0TZ52, AROQ_FRAP2 ;  Q14IY5, AROQ_FRAT1 ;  A7NDV1, AROQ_FRATF ;
DR   Q2A220, AROQ_FRATH ;  B2SDP9, AROQ_FRATM ;  A0Q5E2, AROQ_FRATN ;
DR   Q0BKP9, AROQ_FRATO ;  Q5NHI3, AROQ_FRATT ;  A4IZE9, AROQ_FRATW ;
DR   Q8RH64, AROQ_FUSNN ;  C1A4E4, AROQ_GEMAT ;  B3E9N5, AROQ_GEOLS ;
DR   Q39X01, AROQ_GEOMG ;  B9M3I1, AROQ_GEOSF ;  Q74BL9, AROQ_GEOSL ;
DR   A5GF08, AROQ_GEOUR ;  Q7NHU3, AROQ_GLOVI ;  Q7VNC2, AROQ_HAEDU ;
DR   Q4QLT8, AROQ_HAEI8 ;  A5UDA0, AROQ_HAEIE ;  A5UIB2, AROQ_HAEIG ;
DR   P43878, AROQ_HAEIN ;  B8F6C8, AROQ_HAEPS ;  Q0I1Y1, AROQ_HAES1 ;
DR   B0UV80, AROQ_HAES2 ;  Q2S9M0, AROQ_HAHCH ;  A1WZI8, AROQ_HALHL ;
DR   B8D2E3, AROQ_HALOH ;  Q17WS3, AROQ_HELAH ;  Q7VHM1, AROQ_HELHP ;
DR   B6JKY5, AROQ_HELP2 ;  B5Z6F6, AROQ_HELPG ;  Q1CU96, AROQ_HELPH ;
DR   Q9ZM37, AROQ_HELPJ ;  B2USP3, AROQ_HELPS ;  Q48255, AROQ_HELPY ;
DR   A9B3N9, AROQ_HERA2 ;  A4G8P1, AROQ_HERAR ;  Q0C000, AROQ_HYPNA ;
DR   Q5QVU2, AROQ_IDILO ;  A6T2B3, AROQ_JANMA ;  Q28PZ5, AROQ_JANSC ;
DR   A6W6P9, AROQ_KINRD ;  B5XNE4, AROQ_KLEP3 ;  C1DCV6, AROQ_LARHH ;
DR   Q5X7S5, AROQ_LEGPA ;  A5IHD0, AROQ_LEGPC ;  Q5ZYA8, AROQ_LEGPH ;
DR   Q5WZ76, AROQ_LEGPL ;  B1XX46, AROQ_LEPCP ;  Q65RL3, AROQ_MANSM ;
DR   A1U695, AROQ_MARAV ;  Q0AQ78, AROQ_MARMM ;  A6W284, AROQ_MARMS ;
DR   Q11HL6, AROQ_MESSB ;  Q60A28, AROQ_METCA ;  B1LXE5, AROQ_METRJ ;
DR   Q2RI90, AROQ_MOOTA ;  A0QI58, AROQ_MYCA1 ;  B1MCE8, AROQ_MYCA9 ;
DR   P0A4Z7, AROQ_MYCBO ;  A1KLN4, AROQ_MYCBP ;  C1AF05, AROQ_MYCBT ;
DR   B8ZUK3, AROQ_MYCLB ;  Q9CCS3, AROQ_MYCLE ;  Q741J6, AROQ_MYCPA ;
DR   A5U5N6, AROQ_MYCTA ;  P0A4Z6, AROQ_MYCTU ;  B9L5V9, AROQ_NAUPA ;
DR   Q0AEU9, AROQ_NITEC ;  Q82WL9, AROQ_NITEU ;  Q1QLB8, AROQ_NITHX ;
DR   Q3JC85, AROQ_NITOC ;  A6Q235, AROQ_NITSB ;  Q3SRS9, AROQ_NITWN ;
DR   Q8YTE0, AROQ_NOSS1 ;  B6JHG1, AROQ_OLICO ;  P57903, AROQ_PASMU ;
DR   C6DIK5, AROQ_PECCP ;  Q3A2J0, AROQ_PELCD ;  B4SGR9, AROQ_PELPB ;
DR   A1ARJ7, AROQ_PELPD ;  A5D337, AROQ_PELTS ;  B4RCS3, AROQ_PHEZH ;
DR   Q7N030, AROQ_PHOLL ;  Q6LLZ0, AROQ_PHOPR ;  B1XT51, AROQ_POLNS ;
DR   A4SVB8, AROQ_POLSQ ;  A3PBA5, AROQ_PROM0 ;  A2C0J2, AROQ_PROM1 ;
DR   A8G399, AROQ_PROM2 ;  A9BE04, AROQ_PROM4 ;  A2BV47, AROQ_PROM5 ;
DR   Q7VDJ2, AROQ_PROMA ;  B4EX28, AROQ_PROMH ;  Q7V8X7, AROQ_PROMM ;
DR   Q7V2S9, AROQ_PROMP ;  A2BPL5, AROQ_PROMS ;  Q46H25, AROQ_PROMT ;
DR   Q48DI3, AROQ_PSE14 ;  Q3IDT2, AROQ_PSEHT ;  A4XQ67, AROQ_PSEMY ;
DR   Q87VS6, AROQ_PSESM ;  Q4ZN43, AROQ_PSEU2 ;  A4VPK2, AROQ_PSEU5 ;
DR   A1SZA3, AROQ_PSYIN ;  B2UCE8, AROQ_RALPJ ;  B3PXY7, AROQ_RHIE6 ;
DR   Q1MHI1, AROQ_RHIL3 ;  Q98NC1, AROQ_RHILO ;  Q92QJ9, AROQ_RHIME ;
DR   Q2IVP0, AROQ_RHOP2 ;  Q07MB1, AROQ_RHOP5 ;  Q6N726, AROQ_RHOPA ;
DR   Q213M1, AROQ_RHOPB ;  B3QH35, AROQ_RHOPT ;  A3PP56, AROQ_RHOS1 ;
DR   Q3IWV4, AROQ_RHOS4 ;  B9KTM3, AROQ_RHOSK ;  A7NQC5, AROQ_ROSCS ;
DR   A5UYA1, AROQ_ROSS1 ;  Q21MK4, AROQ_SACD2 ;  A4FBE9, AROQ_SACEN ;
DR   A8LY09, AROQ_SALAI ;  A4X610, AROQ_SALTO ;  B8ECJ0, AROQ_SHEB2 ;
DR   A3CZT7, AROQ_SHEB5 ;  A6WT39, AROQ_SHEB8 ;  A9L4M4, AROQ_SHEB9 ;
DR   Q12J15, AROQ_SHEDO ;  Q07X44, AROQ_SHEFN ;  B0TS36, AROQ_SHEHH ;
DR   A3QID1, AROQ_SHELP ;  Q8EJF5, AROQ_SHEON ;  A4YAS7, AROQ_SHEPC ;
DR   B8CTL3, AROQ_SHEPW ;  A0KSI2, AROQ_SHESA ;  A8G0R9, AROQ_SHESH ;
DR   Q0HMX6, AROQ_SHESM ;  Q0HQV5, AROQ_SHESR ;  A1RFJ9, AROQ_SHESW ;
DR   B1KR25, AROQ_SHEWM ;  Q5LRZ7, AROQ_SILPO ;  Q1GJU6, AROQ_SILST ;
DR   A6U828, AROQ_SINMW ;  Q2NWP6, AROQ_SODGM ;  Q829X9, AROQ_STRAW ;
DR   P15474, AROQ_STRCO ;  B4SKN8, AROQ_STRM5 ;  B2FJN5, AROQ_STRMK ;
DR   Q30SR5, AROQ_SULDN ;  A6Q936, AROQ_SULNB ;  A5GJ60, AROQ_SYNPW ;
DR   Q7U4X5, AROQ_SYNPX ;  A5GR50, AROQ_SYNR3 ;  Q3AWG6, AROQ_SYNS9 ;
DR   Q3AMA6, AROQ_SYNSC ;  P73367, AROQ_SYNY3 ;  C5BP61, AROQ_TERTT ;
DR   Q8DLJ7, AROQ_THEEB ;  Q9WYI4, AROQ_THEMA ;  B9KBV1, AROQ_THENN ;
DR   A5IK69, AROQ_THEP1 ;  B0K9C6, AROQ_THEP3 ;  B0K0T3, AROQ_THEPX ;
DR   B1L9E1, AROQ_THESQ ;  Q72IZ2, AROQ_THET2 ;  Q5SIL5, AROQ_THET8 ;
DR   Q8RAE4, AROQ_THETN ;  Q31II2, AROQ_THICR ;  B8GUV7, AROQ_THISH ;
DR   C4LAE7, AROQ_TOLAT ;  Q111G7, AROQ_TRIEI ;  B1GZJ3, AROQ_UNCTG ;
DR   C5CU07, AROQ_VARPS ;  A5CVG7, AROQ_VESOH ;  A5F3S6, AROQ_VIBC3 ;
DR   Q9KV60, AROQ_VIBCH ;  C3LQQ3, AROQ_VIBCM ;  B5FC62, AROQ_VIBFM ;
DR   Q87KU6, AROQ_VIBPA ;  Q8DD00, AROQ_VIBVU ;  Q7MGU2, AROQ_VIBVY ;
DR   Q7M8I1, AROQ_WOLSU ;  Q8PPZ9, AROQ_XANAC ;  Q3BY66, AROQ_XANC5 ;
DR   Q4UZB2, AROQ_XANC8 ;  B0RN47, AROQ_XANCB ;  Q8PD27, AROQ_XANCP ;
DR   Q2P849, AROQ_XANOM ;  B2SR68, AROQ_XANOP ;  B2I663, AROQ_XYLF2 ;
DR   Q9PH97, AROQ_XYLFA ;  Q87F94, AROQ_XYLFT ;  A1JRK0, AROQ_YERE8 ;
DR   A7FDQ8, AROQ_YERP3 ;  Q1C1N7, AROQ_YERPA ;  B2K461, AROQ_YERPB ;
DR   Q8ZAX1, AROQ_YERPE ;  A9R1Y4, AROQ_YERPG ;  Q1CDU2, AROQ_YERPN ;
DR   A4THC4, AROQ_YERPP ;  Q665E8, AROQ_YERPS ;  B1JKF8, AROQ_YERPY ;
DR   Q9SQT8, DHQSD_ARATH;
//
ID   4.2.1.11
DE   Phosphopyruvate hydratase.
AN   2-phosphoglycerate dehydratase.
AN   Enolase.
CA   2-phospho-D-glycerate = phosphoenolpyruvate + H(2)O.
CF   Magnesium.
CC   -!- Also acts on 3-phospho-D-erythronate.
PR   PROSITE; PDOC00148;
DR   P40370, ENO11_SCHPO;  Q8NKC2, ENO12_SCHPO;  Q9C9C4, ENO1_ARATH ;
DR   P30575, ENO1_CANAL ;  Q6FTW6, ENO1_CANGA ;  Q8KB35, ENO1_CHLTE ;
DR   Q6BTB1, ENO1_DEBHA ;  Q24YW4, ENO1_DESHY ;  P51555, ENO1_ENTHI ;
DR   Q9LEJ0, ENO1_HEVBR ;  Q043Z5, ENO1_LACGA ;  Q74K78, ENO1_LACJO ;
DR   Q9CHS7, ENO1_LACLA ;  Q032H8, ENO1_LACLS ;  Q88YH3, ENO1_LACPL ;
DR   P26301, ENO1_MAIZE ;  Q606T2, ENO1_METCA ;  Q2FQL9, ENO1_METHJ ;
DR   Q886M3, ENO1_PSESM ;  Q4ZWQ8, ENO1_PSEU2 ;  Q1LPI5, ENO1_RALME ;
DR   Q9F2Q3, ENO1_STRCO ;  Q9UAE6, ENO1_TOXGO ;  P00924, ENO1_YEAST ;
DR   P25696, ENO2_ARATH ;  Q6FQY4, ENO2_CANGA ;  Q8KG25, ENO2_CHLTE ;
DR   Q6BI20, ENO2_DEBHA ;  Q24MW5, ENO2_DESHY ;  Q9LEI9, ENO2_HEVBR ;
DR   Q042F4, ENO2_LACGA ;  Q74J64, ENO2_LACJO ;  Q9CIT0, ENO2_LACLA ;
DR   Q030Y9, ENO2_LACLS ;  Q88VW2, ENO2_LACPL ;  P42895, ENO2_MAIZE ;
DR   Q604M4, ENO2_METCA ;  Q2FLB5, ENO2_METHJ ;  Q87WD5, ENO2_PSESM ;
DR   Q4ZWE0, ENO2_PSEU2 ;  Q1LP64, ENO2_RALME ;  Q9F3P9, ENO2_STRCO ;
DR   Q9BPL7, ENO2_TOXGO ;  P00925, ENO2_YEAST ;  Q9ZW34, ENO3_ARATH ;
DR   Q74IV0, ENO3_LACJO ;  Q2FTN3, ENO3_METHJ ;  Q9PVK2, ENOA_ALLMI ;
DR   P19140, ENOA_ANAPL ;  Q9XSJ4, ENOA_BOVIN ;  P51913, ENOA_CHICK ;
DR   Q54RK5, ENOA_DICDI ;  P06733, ENOA_HUMAN ;  Q4R5L2, ENOA_MACFA ;
DR   P86210, ENOA_MESAU ;  P17182, ENOA_MOUSE ;  Q5R6Y1, ENOA_PONAB ;
DR   Q9W7L0, ENOA_PYTRG ;  P04764, ENOA_RAT   ;  Q9W7L2, ENOA_SCEUN ;
DR   Q9W7L1, ENOA_TRASC ;  P08734, ENOA_XENLA ;  Q3ZC09, ENOB_BOVIN ;
DR   P07322, ENOB_CHICK ;  Q55F83, ENOB_DICDI ;  P13929, ENOB_HUMAN ;
DR   P21550, ENOB_MOUSE ;  Q1KYT0, ENOB_PIG   ;  P25704, ENOB_RABIT ;
DR   P15429, ENOB_RAT   ;  O57391, ENOG_CHICK ;  P09104, ENOG_HUMAN ;
DR   P17183, ENOG_MOUSE ;  P07323, ENOG_RAT   ;  B0C9F0, ENO_ACAM1  ;
DR   A9NF93, ENO_ACHLI  ;  A1TLS5, ENO_ACIAC  ;  Q6FAT9, ENO_ACIAD  ;
DR   B7H227, ENO_ACIB3  ;  B7I918, ENO_ACIB5  ;  B2I2A5, ENO_ACIBC  ;
DR   Q1ISS7, ENO_ACIBL  ;  B0VQI4, ENO_ACIBS  ;  A3M5Y1, ENO_ACIBT  ;
DR   B0V677, ENO_ACIBY  ;  A0LW71, ENO_ACIC1  ;  C1F9E6, ENO_ACIC5  ;
DR   A5FUW3, ENO_ACICJ  ;  B9MEQ4, ENO_ACIET  ;  B7J6R4, ENO_ACIF2  ;
DR   B5EPM7, ENO_ACIF5  ;  A1W4R1, ENO_ACISJ  ;  A3N1B9, ENO_ACTP2  ;
DR   B3GY00, ENO_ACTP7  ;  B0BQ53, ENO_ACTPJ  ;  A6VR00, ENO_ACTSZ  ;
DR   A0KGH3, ENO_AERHH  ;  Q8GE63, ENO_AERHY  ;  Q9Y927, ENO_AERPE  ;
DR   A4SRC1, ENO_AERS4  ;  B9JEY7, ENO_AGRRK  ;  Q8UFH1, ENO_AGRT5  ;
DR   B9JW75, ENO_AGRVS  ;  Q0VQD6, ENO_ALCBS  ;  Q0A7K4, ENO_ALHEH  ;
DR   B6EKL8, ENO_ALISL  ;  A6TU30, ENO_ALKMQ  ;  A8MFY2, ENO_ALKOO  ;
DR   P42897, ENO_ALLMI  ;  Q43321, ENO_ALNGL  ;  Q9HDT3, ENO_ALTAL  ;
DR   B4RVU5, ENO_ALTMD  ;  B3EUH8, ENO_AMOA5  ;  B8JAC4, ENO_ANAD2  ;
DR   Q2IID9, ENO_ANADE  ;  A7HCC4, ENO_ANADF  ;  Q5PAS6, ENO_ANAMM  ;
DR   Q2GK24, ENO_ANAPZ  ;  B4UDM8, ENO_ANASK  ;  B9MS47, ENO_ANATD  ;
DR   Q3M7B2, ENO_ANAVT  ;  O66778, ENO_AQUAE  ;  A8EWY0, ENO_ARCB4  ;
DR   O29133, ENO_ARCFU  ;  Q5NZ69, ENO_AROAE  ;  A1R485, ENO_ARTAT  ;
DR   B8HEU5, ENO_ARTCA  ;  A0JU21, ENO_ARTS2  ;  Q756H2, ENO_ASHGO  ;
DR   Q96X30, ENO_ASPFU  ;  Q12560, ENO_ASPOR  ;  Q2NJ39, ENO_AYWBP  ;
DR   A8IBF3, ENO_AZOC5  ;  B6YQN5, ENO_AZOPC  ;  A1K7F6, ENO_AZOSB  ;
DR   A7Z8Y1, ENO_BACA2  ;  C3P0A3, ENO_BACAA  ;  C3LDI0, ENO_BACAC  ;
DR   A0RKS3, ENO_BACAH  ;  Q81X78, ENO_BACAN  ;  B7JFG3, ENO_BACC0  ;
DR   Q72XY5, ENO_BACC1  ;  B7IP20, ENO_BACC2  ;  C1EZA0, ENO_BACC3  ;
DR   B7HED2, ENO_BACC4  ;  B7HW52, ENO_BACC7  ;  A7GUR7, ENO_BACCN  ;
DR   B9J4M4, ENO_BACCQ  ;  Q815K8, ENO_BACCR  ;  Q631M2, ENO_BACCZ  ;
DR   Q5LG64, ENO_BACFN  ;  Q8KNX9, ENO_BACFR  ;  Q9K717, ENO_BACHD  ;
DR   Q6HBF3, ENO_BACHK  ;  Q65EN2, ENO_BACLD  ;  A8FHJ0, ENO_BACP2  ;
DR   Q5WDK9, ENO_BACSK  ;  P37869, ENO_BACSU  ;  Q89Z05, ENO_BACTN  ;
DR   A6L3M9, ENO_BACV8  ;  A9VQ48, ENO_BACWK  ;  A1US94, ENO_BARBK  ;
DR   Q8L202, ENO_BARHE  ;  Q6G173, ENO_BARQU  ;  A9IS50, ENO_BART1  ;
DR   Q1LTN8, ENO_BAUCH  ;  Q6MPQ2, ENO_BDEBA  ;  B2IKR4, ENO_BEII9  ;
DR   C5C093, ENO_BEUC1  ;  B8DTI9, ENO_BIFA0  ;  A1A143, ENO_BIFAA  ;
DR   B3DSV2, ENO_BIFLD  ;  Q8G5I9, ENO_BIFLO  ;  B7GTK2, ENO_BIFLS  ;
DR   Q7VQH3, ENO_BLOFL  ;  Q493N5, ENO_BLOPB  ;  Q2L088, ENO_BORA1  ;
DR   Q0SNH5, ENO_BORAP  ;  Q7WD75, ENO_BORBR  ;  O51312, ENO_BORBU  ;
DR   B7J1R2, ENO_BORBZ  ;  B5RLS2, ENO_BORDL  ;  Q661T0, ENO_BORGA  ;
DR   B2S044, ENO_BORHD  ;  Q7W5N9, ENO_BORPA  ;  A9IIP8, ENO_BORPD  ;
DR   Q7VW79, ENO_BORPE  ;  B5RRF1, ENO_BORRA  ;  Q89KV6, ENO_BRAJA  ;
DR   A5EK13, ENO_BRASB  ;  A4YVC0, ENO_BRASO  ;  C0Z6L3, ENO_BREBN  ;
DR   B2S5Y3, ENO_BRUA1  ;  Q2YPV0, ENO_BRUA2  ;  Q57D07, ENO_BRUAB  ;
DR   A9M5E5, ENO_BRUC2  ;  C0RJA3, ENO_BRUMB  ;  Q8YHF0, ENO_BRUME  ;
DR   A5VQQ7, ENO_BRUO2  ;  B0CGT2, ENO_BRUSI  ;  Q8G0G3, ENO_BRUSU  ;
DR   B8D9J5, ENO_BUCA5  ;  P57492, ENO_BUCAI  ;  Q8K9E0, ENO_BUCAP  ;
DR   B8D7U7, ENO_BUCAT  ;  P59566, ENO_BUCBP  ;  Q057H3, ENO_BUCCC  ;
DR   B1YT09, ENO_BURA4  ;  Q1BHS0, ENO_BURCA  ;  B1JUY6, ENO_BURCC  ;
DR   A0K8N1, ENO_BURCH  ;  B4EDA1, ENO_BURCJ  ;  Q0BDS3, ENO_BURCM  ;
DR   A9AGW2, ENO_BURM1  ;  A3ML77, ENO_BURM7  ;  A2SAU7, ENO_BURM9  ;
DR   Q62J10, ENO_BURMA  ;  A1V5K2, ENO_BURMS  ;  A3NX13, ENO_BURP0  ;
DR   Q3JQQ6, ENO_BURP1  ;  A3NB82, ENO_BURP6  ;  B2JIX0, ENO_BURP8  ;
DR   B2SXU9, ENO_BURPP  ;  Q63SQ0, ENO_BURPS  ;  Q39EV9, ENO_BURS3  ;
DR   Q2SXC5, ENO_BURTA  ;  A4JFY5, ENO_BURVG  ;  Q13X07, ENO_BURXL  ;
DR   Q27527, ENO_CAEEL  ;  A4XKV0, ENO_CALS8  ;  A7ZFN1, ENO_CAMC1  ;
DR   A7H0M5, ENO_CAMC5  ;  O30885, ENO_CAMFE  ;  A0RMH2, ENO_CAMFF  ;
DR   A7I455, ENO_CAMHC  ;  A8FNY3, ENO_CAMJ8  ;  A7H622, ENO_CAMJD  ;
DR   P42448, ENO_CAMJE  ;  A1W1S4, ENO_CAMJJ  ;  Q5HSC1, ENO_CAMJR  ;
DR   B9KEN0, ENO_CAMLR  ;  Q3AFC8, ENO_CARHZ  ;  B8GW68, ENO_CAUCN  ;
DR   Q9A7J9, ENO_CAUCR  ;  B0SYX8, ENO_CAUSK  ;  B3PJB3, ENO_CELJU  ;
DR   A9WCM4, ENO_CHLAA  ;  Q5L4S5, ENO_CHLAB  ;  B8GAX5, ENO_CHLAD  ;
DR   Q3ATQ5, ENO_CHLCH  ;  Q821H7, ENO_CHLCV  ;  Q256G5, ENO_CHLFF  ;
DR   B3EEQ2, ENO_CHLL2  ;  Q9PJF3, ENO_CHLMU  ;  B3QQT2, ENO_CHLP8  ;
DR   B3EL51, ENO_CHLPB  ;  A1BD13, ENO_CHLPD  ;  Q9Z7A6, ENO_CHLPN  ;
DR   P31683, ENO_CHLRE  ;  B0B8G1, ENO_CHLT2  ;  B3QXY4, ENO_CHLT3  ;
DR   Q3KLB0, ENO_CHLTA  ;  B0BA40, ENO_CHLTB  ;  O84591, ENO_CHLTR  ;
DR   Q1QZX7, ENO_CHRSD  ;  A5CTA8, ENO_CLAM3  ;  B0RH60, ENO_CLAMS  ;
DR   Q97L52, ENO_CLOAB  ;  A7FQP0, ENO_CLOB1  ;  C3KZ49, ENO_CLOB6  ;
DR   A6LR09, ENO_CLOB8  ;  B2UY16, ENO_CLOBA  ;  B2TPW4, ENO_CLOBB  ;
DR   C1FQW6, ENO_CLOBJ  ;  B1IDB9, ENO_CLOBK  ;  A7G9Y3, ENO_CLOBL  ;
DR   B1KTJ8, ENO_CLOBM  ;  B8I4U1, ENO_CLOCE  ;  Q181T5, ENO_CLOD6  ;
DR   Q7M0V7, ENO_CLODI  ;  B9E6B1, ENO_CLOK1  ;  A5N2N5, ENO_CLOK5  ;
DR   A0PYP4, ENO_CLONN  ;  Q0TQZ2, ENO_CLOP1  ;  Q8XKU4, ENO_CLOPE  ;
DR   A9KQ46, ENO_CLOPH  ;  Q0STE0, ENO_CLOPS  ;  Q898R0, ENO_CLOTE  ;
DR   A3DBQ5, ENO_CLOTH  ;  Q47WR1, ENO_COLP3  ;  C3PFA7, ENO_CORA7  ;
DR   Q6NI61, ENO_CORDI  ;  Q8FQS7, ENO_COREF  ;  A4QCV0, ENO_CORGB  ;
DR   Q8NRS1, ENO_CORGL  ;  Q4JU51, ENO_CORJK  ;  C4LHL7, ENO_CORK4  ;
DR   B1VFL0, ENO_CORU7  ;  B6J4X4, ENO_COXB1  ;  B6J3X4, ENO_COXB2  ;
DR   A9KDH7, ENO_COXBN  ;  A9N9U9, ENO_COXBR  ;  Q83B44, ENO_COXBU  ;
DR   Q6RG04, ENO_CRYPA  ;  O74286, ENO_CUNEL  ;  Q0KCE2, ENO_CUPNH  ;
DR   Q473G4, ENO_CUPPJ  ;  B3R499, ENO_CUPTR  ;  Q96VP4, ENO_CURLU  ;
DR   B8HQY9, ENO_CYAP4  ;  B7KL24, ENO_CYAP7  ;  B7JW48, ENO_CYAP8  ;
DR   Q11QE1, ENO_CYTH3  ;  P42040, ENO_DAVTA  ;  Q47DI1, ENO_DECAR  ;
DR   Q3Z8W4, ENO_DEHE1  ;  A5FRM5, ENO_DEHSB  ;  Q3ZX11, ENO_DEHSC  ;
DR   C1CXJ3, ENO_DEIDV  ;  Q1J2H6, ENO_DEIGD  ;  Q9RR60, ENO_DEIRA  ;
DR   B8FKT4, ENO_DESAA  ;  C6BSL8, ENO_DESAD  ;  C0QI43, ENO_DESAH  ;
DR   B8J467, ENO_DESDA  ;  Q316Q0, ENO_DESDG  ;  C4XLR9, ENO_DESMR  ;
DR   A8ZSY5, ENO_DESOH  ;  Q6AM97, ENO_DESPS  ;  Q72F92, ENO_DESVH  ;
DR   O32513, ENO_DESVM  ;  A1VGV5, ENO_DESVV  ;  A5EW24, ENO_DICNV  ;
DR   B5YF30, ENO_DICT6  ;  B8E0W1, ENO_DICTD  ;  A8LQL4, ENO_DINSH  ;
DR   P15007, ENO_DROME  ;  A7ZQM2, ENO_ECO24  ;  B7UHJ5, ENO_ECO27  ;
DR   B7MLA0, ENO_ECO45  ;  B7LEJ8, ENO_ECO55  ;  P0A6Q1, ENO_ECO57  ;
DR   B5Z3E3, ENO_ECO5E  ;  B7NV69, ENO_ECO7I  ;  B7MZ75, ENO_ECO81  ;
DR   B7LXJ5, ENO_ECO8A  ;  C4ZZT2, ENO_ECOBW  ;  B1XDI9, ENO_ECODH  ;
DR   A8A3R4, ENO_ECOHS  ;  A1AEW7, ENO_ECOK1  ;  Q0TE80, ENO_ECOL5  ;
DR   P0A6Q0, ENO_ECOL6  ;  B1IU62, ENO_ECOLC  ;  P0A6P9, ENO_ECOLI  ;
DR   B7N715, ENO_ECOLU  ;  B6I6H5, ENO_ECOSE  ;  B1LQB2, ENO_ECOSM  ;
DR   Q1R7R4, ENO_ECOUT  ;  C5B8X2, ENO_EDWI9  ;  Q3YRX9, ENO_EHRCJ  ;
DR   Q2GGS6, ENO_EHRCR  ;  Q5FH95, ENO_EHRRG  ;  Q5HB46, ENO_EHRRW  ;
DR   Q967Y8, ENO_EIMTE  ;  B2KBA5, ENO_ELUMP  ;  Q5B135, ENO_EMENI  ;
DR   A4WDW7, ENO_ENT38  ;  Q9K596, ENO_ENTFA  ;  Q8GR70, ENO_ENTHR  ;
DR   A7MQZ0, ENO_ENTS8  ;  Q6D182, ENO_ERWCT  ;  B2VFY8, ENO_ERWT9  ;
DR   Q2NAQ1, ENO_ERYLH  ;  B7LWP5, ENO_ESCF3  ;  C4Z1M9, ENO_EUBE2  ;
DR   B1YLD8, ENO_EXIS2  ;  C4L5H4, ENO_EXISA  ;  Q27655, ENO_FASHE  ;
DR   A7HNS8, ENO_FERNB  ;  B0S1G7, ENO_FINM2  ;  A5FN12, ENO_FLAJ1  ;
DR   A6GZ69, ENO_FLAPJ  ;  Q0RCG8, ENO_FRAAA  ;  Q2J619, ENO_FRASC  ;
DR   A8L149, ENO_FRASN  ;  Q14IC0, ENO_FRAT1  ;  Q2A278, ENO_FRATH  ;
DR   A0Q5J9, ENO_FRATN  ;  Q0BKV1, ENO_FRATO  ;  Q5NGW8, ENO_FRATT  ;
DR   Q8RI55, ENO_FUSNN  ;  C1A7Y3, ENO_GEMAT  ;  B5EGF2, ENO_GEOBB  ;
DR   Q5KVE7, ENO_GEOKA  ;  B3E2S8, ENO_GEOLS  ;  Q39T27, ENO_GEOMG  ;
DR   B9M3M1, ENO_GEOSF  ;  Q74AR6, ENO_GEOSL  ;  C6E471, ENO_GEOSM  ;
DR   C5D7M1, ENO_GEOSW  ;  A4ISP4, ENO_GEOTN  ;  A5GEW5, ENO_GEOUR  ;
DR   Q7NIR1, ENO_GLOVI  ;  A9HJ75, ENO_GLUDA  ;  Q5FNN5, ENO_GLUOX  ;
DR   Q0BSX3, ENO_GRABC  ;  A0M568, ENO_GRAFK  ;  Q7VNM6, ENO_HAEDU  ;
DR   Q4QLX6, ENO_HAEI8  ;  A5UDD6, ENO_HAEIE  ;  A5UI73, ENO_HAEIG  ;
DR   P43806, ENO_HAEIN  ;  B8F8L5, ENO_HAEPS  ;  Q0I1Z1, ENO_HAES1  ;
DR   B0UV89, ENO_HAES2  ;  Q2SKX0, ENO_HAHCH  ;  A1WWZ2, ENO_HALHL  ;
DR   B9LPW6, ENO_HALLT  ;  P29201, ENO_HALMA  ;  B0R4Y8, ENO_HALS3  ;
DR   Q9HQI9, ENO_HALSA  ;  Q18G62, ENO_HALWD  ;  C4K4K1, ENO_HAMD5  ;
DR   Q17YV0, ENO_HELAH  ;  Q7VIH4, ENO_HELHP  ;  B6JPQ2, ENO_HELP2  ;
DR   B5Z9S9, ENO_HELPG  ;  Q1CV03, ENO_HELPH  ;  Q9ZMS6, ENO_HELPJ  ;
DR   B2URY4, ENO_HELPS  ;  P48285, ENO_HELPY  ;  A4G737, ENO_HERAR  ;
DR   P56252, ENO_HOMGA  ;  B4U9X7, ENO_HYDS0  ;  Q0C0R3, ENO_HYPNA  ;
DR   Q5R143, ENO_IDILO  ;  P84208, ENO_IMPCY  ;  A6SXG3, ENO_JANMA  ;
DR   Q28RE8, ENO_JANSC  ;  A6W6X2, ENO_KINRD  ;  B5XV19, ENO_KLEP3  ;
DR   A6TD53, ENO_KLEP7  ;  Q70CP7, ENO_KLULA  ;  B2GM13, ENO_KOCRD  ;
DR   Q5FKM6, ENO_LACAC  ;  Q03SL5, ENO_LACBA  ;  Q03AK4, ENO_LACC3  ;
DR   B3WCW7, ENO_LACCB  ;  Q1G9S9, ENO_LACDA  ;  Q049Y3, ENO_LACDB  ;
DR   B2GAM0, ENO_LACF3  ;  A8YUV4, ENO_LACH4  ;  A2RIX1, ENO_LACLM  ;
DR   Q1WSY0, ENO_LACS1  ;  Q38Y18, ENO_LACSS  ;  C1DCC3, ENO_LARHH  ;
DR   Q1MS78, ENO_LAWIP  ;  Q5X3L4, ENO_LEGPA  ;  A5IDM2, ENO_LEGPC  ;
DR   Q5ZTX1, ENO_LEGPH  ;  Q5WV02, ENO_LEGPL  ;  Q6ADR6, ENO_LEIXX  ;
DR   B0S8S8, ENO_LEPBA  ;  Q04SI9, ENO_LEPBJ  ;  Q050L5, ENO_LEPBL  ;
DR   B0SRL5, ENO_LEPBP  ;  B1Y4K4, ENO_LEPCP  ;  Q72QZ8, ENO_LEPIC  ;
DR   Q8F4T8, ENO_LEPIN  ;  B1MVW3, ENO_LEUCK  ;  Q03ZK4, ENO_LEUMM  ;
DR   P64075, ENO_LISIN  ;  C1KY94, ENO_LISMC  ;  Q71WX1, ENO_LISMF  ;
DR   B8DDA1, ENO_LISMH  ;  P64074, ENO_LISMO  ;  A0ALD9, ENO_LISW6  ;
DR   O02654, ENO_LOLPE  ;  B1HVS4, ENO_LYSSC  ;  B9EAH1, ENO_MACCJ  ;
DR   Q2W698, ENO_MAGSA  ;  A0L7X8, ENO_MAGSM  ;  Q65VZ7, ENO_MANSM  ;
DR   A1TZ48, ENO_MARAV  ;  Q0APT2, ENO_MARMM  ;  A6VUU9, ENO_MARMS  ;
DR   Q9U615, ENO_MASBA  ;  Q43130, ENO_MESCR  ;  Q6F0Z7, ENO_MESFL  ;
DR   Q11HU8, ENO_MESSB  ;  A6UUM2, ENO_META3  ;  Q8TQ79, ENO_METAC  ;
DR   Q468E2, ENO_METBF  ;  Q12VE5, ENO_METBU  ;  B7KRB4, ENO_METC4  ;
DR   A9W6G9, ENO_METEP  ;  Q1H011, ENO_METFK  ;  Q60173, ENO_METJA  ;
DR   Q8TUV6, ENO_METKA  ;  A2SSV1, ENO_METLZ  ;  A4FZA6, ENO_METM5  ;
DR   A6VJ31, ENO_METM7  ;  Q8PT81, ENO_METMA  ;  Q6M075, ENO_METMP  ;
DR   B1ZEJ8, ENO_METPB  ;  A2SJR2, ENO_METPP  ;  B1LZU6, ENO_METRJ  ;
DR   A4YHC1, ENO_METS5  ;  B8EJT3, ENO_METSB  ;  Q2NG02, ENO_METST  ;
DR   O26149, ENO_METTH  ;  A0B7E8, ENO_METTP  ;  A6US08, ENO_METVS  ;
DR   B0JMP6, ENO_MICAN  ;  C5C987, ENO_MICLC  ;  Q2RLT8, ENO_MOOTA  ;
DR   A0QBX4, ENO_MYCA1  ;  B3PNH6, ENO_MYCA5  ;  B1MKG1, ENO_MYCA9  ;
DR   A5IYA8, ENO_MYCAP  ;  Q7U0U6, ENO_MYCBO  ;  A1KHG1, ENO_MYCBP  ;
DR   C1AM14, ENO_MYCBT  ;  Q2SSR3, ENO_MYCCT  ;  Q7NAY0, ENO_MYCGA  ;
DR   P47647, ENO_MYCGE  ;  A4T6L5, ENO_MYCGI  ;  Q601S2, ENO_MYCH2  ;
DR   Q4A8B5, ENO_MYCH7  ;  Q4AA88, ENO_MYCHJ  ;  Q9CD42, ENO_MYCLE  ;
DR   B2HDI5, ENO_MYCMM  ;  Q6KIB0, ENO_MYCMO  ;  Q6MTZ2, ENO_MYCMS  ;
DR   Q741U7, ENO_MYCPA  ;  Q8EW32, ENO_MYCPE  ;  P75189, ENO_MYCPN  ;
DR   Q98Q50, ENO_MYCPU  ;  A0R3B8, ENO_MYCS2  ;  Q4A740, ENO_MYCS5  ;
DR   A3Q5F7, ENO_MYCSJ  ;  A1UL09, ENO_MYCSK  ;  Q1B439, ENO_MYCSS  ;
DR   A5U166, ENO_MYCTA  ;  A1QQ97, ENO_MYCTF  ;  P96377, ENO_MYCTU  ;
DR   A0PW55, ENO_MYCUA  ;  A1TEE4, ENO_MYCVP  ;  Q1D401, ENO_MYXXD  ;
DR   Q3IQT0, ENO_NATPD  ;  B2A6Z1, ENO_NATTJ  ;  B9L7U3, ENO_NAUPA  ;
DR   Q5F8Z2, ENO_NEIG1  ;  B4RMD8, ENO_NEIG2  ;  A9LZL4, ENO_NEIM0  ;
DR   Q9JU46, ENO_NEIMA  ;  Q9JZ53, ENO_NEIMB  ;  A1KUB6, ENO_NEIMF  ;
DR   P42894, ENO_NEOFR  ;  Q2GD37, ENO_NEOSM  ;  Q7RV85, ENO_NEUCR  ;
DR   Q0AD93, ENO_NITEC  ;  O85348, ENO_NITEU  ;  Q1QMI9, ENO_NITHX  ;
DR   Q2Y9P0, ENO_NITMU  ;  Q3JCT1, ENO_NITOC  ;  A6Q5K4, ENO_NITSB  ;
DR   Q3SRK4, ENO_NITWN  ;  Q5YQ30, ENO_NOCFA  ;  A1SF66, ENO_NOCSJ  ;
DR   B2J1R2, ENO_NOSP7  ;  Q8YRB0, ENO_NOSS1  ;  Q2G662, ENO_NOVAD  ;
DR   Q8ENP5, ENO_OCEIH  ;  A6X0L8, ENO_OCHA4  ;  Q04DH2, ENO_OENOB  ;
DR   B6JFY2, ENO_OLICO  ;  Q6YQT9, ENO_ONYPE  ;  Q42971, ENO_ORYSJ  ;
DR   A1B9D2, ENO_PARDP  ;  A7HXW7, ENO_PARL1  ;  Q6MEY2, ENO_PARUW  ;
DR   P57975, ENO_PASMU  ;  C6DDJ5, ENO_PECCP  ;  Q03GW5, ENO_PEDPA  ;
DR   Q3A578, ENO_PELCD  ;  Q3B1G7, ENO_PELLD  ;  B4SGB2, ENO_PELPB  ;
DR   A1APJ8, ENO_PELPD  ;  Q4FM37, ENO_PELUB  ;  Q76KF9, ENO_PENCH  ;
DR   Q96X46, ENO_PENCI  ;  C0QRV6, ENO_PERMH  ;  A9BIS7, ENO_PETMO  ;
DR   B4RBW1, ENO_PHEZH  ;  Q7N835, ENO_PHOLL  ;  Q6LMT1, ENO_PHOPR  ;
DR   B1V8R6, ENO_PHYAS  ;  Q6KZN3, ENO_PICTO  ;  Q8IJN7, ENO_PLAF7  ;
DR   Q27727, ENO_PLAFA  ;  Q9UAL5, ENO_PLAFG  ;  Q7RA60, ENO_PLAYO  ;
DR   A1VLH1, ENO_POLNA  ;  B1XUR8, ENO_POLNS  ;  Q128E4, ENO_POLSJ  ;
DR   A4SXE9, ENO_POLSQ  ;  P84541, ENO_POPEU  ;  B2RLL7, ENO_PORG3  ;
DR   Q7MTV8, ENO_PORGI  ;  B4S487, ENO_PROA2  ;  Q6AAB8, ENO_PROAC  ;
DR   A3PAS6, ENO_PROM0  ;  A2C038, ENO_PROM1  ;  A8G2L5, ENO_PROM2  ;
DR   A2CDE2, ENO_PROM3  ;  A9BDH2, ENO_PROM4  ;  A2BUI5, ENO_PROM5  ;
DR   Q31CX3, ENO_PROM9  ;  Q7VDY0, ENO_PROMA  ;  B4EUF7, ENO_PROMH  ;
DR   Q7V483, ENO_PROMM  ;  Q7V377, ENO_PROMP  ;  A2BP03, ENO_PROMS  ;
DR   Q46HG5, ENO_PROMT  ;  A4SGL6, ENO_PROVI  ;  Q48F79, ENO_PSE14  ;
DR   Q15QR6, ENO_PSEA6  ;  A6V1F3, ENO_PSEA7  ;  B7V7V4, ENO_PSEA8  ;
DR   Q02RA7, ENO_PSEAB  ;  Q9HXZ5, ENO_PSEAE  ;  Q1I646, ENO_PSEE4  ;
DR   Q4KHF6, ENO_PSEF5  ;  Q3IDM2, ENO_PSEHT  ;  A4XWS1, ENO_PSEMY  ;
DR   Q3KH92, ENO_PSEPF  ;  B0KSB9, ENO_PSEPG  ;  Q88MF9, ENO_PSEPK  ;
DR   B1JB38, ENO_PSEPW  ;  Q4FR74, ENO_PSYA2  ;  Q1Q9K6, ENO_PSYCK  ;
DR   A1SSQ7, ENO_PSYIN  ;  A5WG13, ENO_PSYWF  ;  Q9UXZ0, ENO_PYRAB  ;
DR   Q8ZYE7, ENO_PYRAE  ;  Q8U477, ENO_PYRFU  ;  O59605, ENO_PYRHO  ;
DR   Q5JEV6, ENO_PYRKO  ;  B2U9C3, ENO_RALPJ  ;  Q8Y0B5, ENO_RALSO  ;
DR   Q2K8W9, ENO_RHIEC  ;  Q1MH36, ENO_RHIL3  ;  Q98MZ3, ENO_RHILO  ;
DR   B5ZNA1, ENO_RHILW  ;  Q92Q98, ENO_RHIME  ;  C3MBJ9, ENO_RHISN  ;
DR   Q7UIR2, ENO_RHOBA  ;  B6IQ30, ENO_RHOCS  ;  C1A306, ENO_RHOE4  ;
DR   Q21V37, ENO_RHOFD  ;  C1AY93, ENO_RHOOB  ;  Q2IWD0, ENO_RHOP2  ;
DR   Q07ND9, ENO_RHOP5  ;  Q6N5U6, ENO_RHOPA  ;  Q215A2, ENO_RHOPB  ;
DR   Q136E5, ENO_RHOPS  ;  B3Q6L0, ENO_RHOPT  ;  Q870B9, ENO_RHORB  ;
DR   Q2RT60, ENO_RHORT  ;  A3PIV3, ENO_RHOS1  ;  Q3J3H9, ENO_RHOS4  ;
DR   A4WR18, ENO_RHOS5  ;  B9KQU4, ENO_RHOSK  ;  Q0S4I1, ENO_RHOSR  ;
DR   P42896, ENO_RICCO  ;  A7NFI9, ENO_ROSCS  ;  Q164E3, ENO_ROSDO  ;
DR   A5V1W0, ENO_ROSS1  ;  Q1AXJ9, ENO_RUBXD  ;  A1AW20, ENO_RUTMC  ;
DR   Q21LC2, ENO_SACD2  ;  A4F804, ENO_SACEN  ;  B5F4N9, ENO_SALA4  ;
DR   A8M2Y3, ENO_SALAI  ;  A9MF11, ENO_SALAR  ;  Q57KH0, ENO_SALCH  ;
DR   B5FTU9, ENO_SALDC  ;  B5QW40, ENO_SALEP  ;  B5RDS5, ENO_SALG2  ;
DR   B4TFZ1, ENO_SALHS  ;  B4T483, ENO_SALNS  ;  Q5PEH4, ENO_SALPA  ;
DR   A9N2F4, ENO_SALPB  ;  C0PXD5, ENO_SALPC  ;  B5BF02, ENO_SALPK  ;
DR   Q2S4F8, ENO_SALRD  ;  B4TTY5, ENO_SALSV  ;  P64077, ENO_SALTI  ;
DR   A4X3B7, ENO_SALTO  ;  P64076, ENO_SALTY  ;  P33676, ENO_SCHJA  ;
DR   Q27877, ENO_SCHMA  ;  A8G9W1, ENO_SERP5  ;  A1S4D7, ENO_SHEAM  ;
DR   B8E8T1, ENO_SHEB2  ;  A3D795, ENO_SHEB5  ;  A6WR28, ENO_SHEB8  ;
DR   A9KYH0, ENO_SHEB9  ;  Q12PZ4, ENO_SHEDO  ;  Q086B0, ENO_SHEFN  ;
DR   B0TK04, ENO_SHEHH  ;  A3QC77, ENO_SHELP  ;  Q8EBR0, ENO_SHEON  ;
DR   A8H1S5, ENO_SHEPA  ;  A4Y943, ENO_SHEPC  ;  B8CJP6, ENO_SHEPW  ;
DR   A0KU82, ENO_SHESA  ;  A8FSS8, ENO_SHESH  ;  Q0HL72, ENO_SHESM  ;
DR   Q0HXH0, ENO_SHESR  ;  A1RHF3, ENO_SHESW  ;  B1KPT6, ENO_SHEWM  ;
DR   B2TZF4, ENO_SHIB3  ;  Q31XL1, ENO_SHIBS  ;  Q32CD6, ENO_SHIDS  ;
DR   Q0T1P7, ENO_SHIF8  ;  P0A6Q2, ENO_SHIFL  ;  Q3YY77, ENO_SHISS  ;
DR   Q5LQL4, ENO_SILPO  ;  Q1GI52, ENO_SILST  ;  A6U8E5, ENO_SINMW  ;
DR   Q2NVN7, ENO_SODGM  ;  P26300, ENO_SOLLC  ;  Q01YD1, ENO_SOLUE  ;
DR   A9FA52, ENO_SORC5  ;  Q1GVS8, ENO_SPHAL  ;  A5V3E8, ENO_SPHWW  ;
DR   A7WZT2, ENO_STAA1  ;  A6TZQ5, ENO_STAA2  ;  Q2FIL7, ENO_STAA3  ;
DR   Q2G028, ENO_STAA8  ;  A5IQY0, ENO_STAA9  ;  Q2YSE8, ENO_STAAB  ;
DR   Q5HHP1, ENO_STAAC  ;  A6QF85, ENO_STAAE  ;  P64078, ENO_STAAM  ;
DR   P99088, ENO_STAAN  ;  Q6GIL4, ENO_STAAR  ;  Q6GB54, ENO_STAAS  ;
DR   A8Z1A4, ENO_STAAT  ;  O69174, ENO_STAAU  ;  P64079, ENO_STAAW  ;
DR   B9DJJ9, ENO_STACT  ;  Q5HQV0, ENO_STAEQ  ;  Q8CPY3, ENO_STAES  ;
DR   Q4L4K7, ENO_STAHJ  ;  Q49W03, ENO_STAS1  ;  Q3K2B2, ENO_STRA1  ;
DR   P64080, ENO_STRA3  ;  P64081, ENO_STRA5  ;  Q8RP81, ENO_STRAG  ;
DR   Q82HH5, ENO_STRAW  ;  C0M6K5, ENO_STRE4  ;  B4U2B8, ENO_STREM  ;
DR   A8AY46, ENO_STRGC  ;  Q9XDS7, ENO_STRIT  ;  B4SR86, ENO_STRM5  ;
DR   B2FK88, ENO_STRMK  ;  Q8DTS9, ENO_STRMU  ;  P69949, ENO_STRP1  ;
DR   Q04KG2, ENO_STRP2  ;  P0DA94, ENO_STRP3  ;  B5E4P1, ENO_STRP4  ;
DR   Q5XD01, ENO_STRP6  ;  C1C7C0, ENO_STRP7  ;  P69951, ENO_STRP8  ;
DR   Q1JCN8, ENO_STRPB  ;  Q1JML5, ENO_STRPC  ;  Q1JHQ6, ENO_STRPD  ;
DR   Q1J7I5, ENO_STRPF  ;  A2RFE3, ENO_STRPG  ;  B1IBR3, ENO_STRPI  ;
DR   B8ZPW9, ENO_STRPJ  ;  Q48UF7, ENO_STRPM  ;  Q97QS2, ENO_STRPN  ;
DR   P0DA95, ENO_STRPQ  ;  B2IPX8, ENO_STRPS  ;  B5XKM7, ENO_STRPZ  ;
DR   Q8DPS0, ENO_STRR6  ;  A4W2T1, ENO_STRS2  ;  C0MH89, ENO_STRS7  ;
DR   A3CMA7, ENO_STRSV  ;  Q5M0M5, ENO_STRT1  ;  Q5M561, ENO_STRT2  ;
DR   Q03LI0, ENO_STRTD  ;  O52191, ENO_STRTR  ;  B9DRR9, ENO_STRU0  ;
DR   C1CEB3, ENO_STRZJ  ;  C1CKJ0, ENO_STRZP  ;  C1CRM6, ENO_STRZT  ;
DR   Q4J920, ENO_SULAC  ;  Q30P06, ENO_SULDN  ;  C3N5G6, ENO_SULIA  ;
DR   C4KH32, ENO_SULIK  ;  C3MPU0, ENO_SULIL  ;  C3MUV2, ENO_SULIM  ;
DR   C3NHN3, ENO_SULIN  ;  C3NE30, ENO_SULIY  ;  Q97ZJ3, ENO_SULSO  ;
DR   B2V9N8, ENO_SULSY  ;  Q972B6, ENO_SULTO  ;  Q67SV9, ENO_SYMTH  ;
DR   Q2LR33, ENO_SYNAS  ;  Q31QJ8, ENO_SYNE7  ;  A0LEC9, ENO_SYNFM  ;
DR   Q2JRS2, ENO_SYNJA  ;  Q2JIT3, ENO_SYNJB  ;  B1XLD0, ENO_SYNP2  ;
DR   Q5N3P4, ENO_SYNP6  ;  A5GPE0, ENO_SYNPW  ;  Q7U3T1, ENO_SYNPX  ;
DR   Q0I6K2, ENO_SYNS3  ;  Q3AVW5, ENO_SYNS9  ;  Q3AGS4, ENO_SYNSC  ;
DR   Q0B080, ENO_SYNWW  ;  P77972, ENO_SYNY3  ;  B7IFN4, ENO_THEAB  ;
DR   Q9HJT1, ENO_THEAC  ;  Q8DL40, ENO_THEEB  ;  Q47SV1, ENO_THEFY  ;
DR   C5A2S7, ENO_THEGJ  ;  A6LJF0, ENO_THEM4  ;  P42848, ENO_THEMA  ;
DR   B9KA91, ENO_THENN  ;  B6YUB8, ENO_THEON  ;  A5IIQ6, ENO_THEP1  ;
DR   B0K882, ENO_THEP3  ;  B0K6X6, ENO_THEPX  ;  B1LCF4, ENO_THESQ  ;
DR   Q72H85, ENO_THET2  ;  Q5SME1, ENO_THET8  ;  Q8R967, ENO_THETN  ;
DR   Q979Z9, ENO_THEVO  ;  Q31G68, ENO_THICR  ;  Q3SL43, ENO_THIDA  ;
DR   B8GQ75, ENO_THISH  ;  C4LBR1, ENO_TOLAT  ;  Q73P50, ENO_TREDE  ;
DR   P74934, ENO_TREPA  ;  B2S455, ENO_TREPS  ;  Q110V4, ENO_TRIEI  ;
DR   Q83H73, ENO_TROW8  ;  Q83FF7, ENO_TROWT  ;  Q6W3C0, ENO_TUBBO  ;
DR   Q0W8C9, ENO_UNCMA  ;  B1GYL7, ENO_UNCTG  ;  B1AIH2, ENO_UREP2  ;
DR   Q9PQV9, ENO_UREPA  ;  B5ZAZ0, ENO_UREU1  ;  C5CSV6, ENO_VARPS  ;
DR   A1WL86, ENO_VEREI  ;  A5CX71, ENO_VESOH  ;  A5F5I3, ENO_VIBC3  ;
DR   Q9KPC5, ENO_VIBCH  ;  C3LQZ0, ENO_VIBCM  ;  Q5E326, ENO_VIBF1  ;
DR   B5FAF9, ENO_VIBFM  ;  Q87LQ0, ENO_VIBPA  ;  Q8DC62, ENO_VIBVU  ;
DR   Q7MHQ1, ENO_VIBVY  ;  Q8D2K1, ENO_WIGBR  ;  Q73HQ2, ENO_WOLPM  ;
DR   B3CNP3, ENO_WOLPP  ;  Q7M8Q0, ENO_WOLSU  ;  Q5GTG4, ENO_WOLTR  ;
DR   C0R5N4, ENO_WOLWR  ;  Q8PLS0, ENO_XANAC  ;  Q3BUT0, ENO_XANC5  ;
DR   Q4UTP2, ENO_XANC8  ;  B0RU05, ENO_XANCB  ;  Q8P9Z3, ENO_XANCP  ;
DR   Q2P1K8, ENO_XANOM  ;  B2SUA6, ENO_XANOP  ;  Q5GYK4, ENO_XANOR  ;
DR   A7INB6, ENO_XANP2  ;  B2I937, ENO_XYLF2  ;  Q9PDT8, ENO_XYLFA  ;
DR   Q87DY6, ENO_XYLFT  ;  Q6C1F3, ENO_YARLI  ;  A1JJR4, ENO_YERE8  ;
DR   A7FLZ5, ENO_YERP3  ;  Q1C3Y6, ENO_YERPA  ;  B2K561, ENO_YERPB  ;
DR   Q8ZBN2, ENO_YERPE  ;  A9R1D1, ENO_YERPG  ;  Q1CLT2, ENO_YERPN  ;
DR   A4TPY1, ENO_YERPP  ;  Q66ED8, ENO_YERPS  ;  B1JK09, ENO_YERPY  ;
DR   P33675, ENO_ZYMMO  ;  P0CX10, ERR1_YEAST ;  P0CX11, ERR2_YEAST ;
DR   P42222, ERR3_YEAST ;
//
ID   4.2.1.12
DE   Phosphogluconate dehydratase.
CA   6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H(2)O.
PR   PROSITE; PDOC00690;
DR   P0ADF7, EDD_ECO57  ;  P0ADF6, EDD_ECOLI  ;  Q9ZKB3, EDD_HELPJ  ;
DR   P56111, EDD_HELPY  ;  P31961, EDD_PSEAE  ;  Q9Z3S0, EDD_RHIME  ;
DR   P21909, EDD_ZYMMO  ;
//
ID   4.2.1.13
DE   Transferred entry: 4.3.1.17.
//
ID   4.2.1.14
DE   Transferred entry: 4.3.1.18.
//
ID   4.2.1.15
DE   Transferred entry: 4.4.1.1.
//
ID   4.2.1.16
DE   Transferred entry: 4.3.1.19.
//
ID   4.2.1.17
DE   Enoyl-CoA hydratase.
AN   Enoyl hydrase.
AN   Unsaturated acyl-CoA hydratase.
CA   (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O.
CC   -!- Acts in the reverse direction.
CC   -!- With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74).
PR   PROSITE; PDOC00150;
DR   Q9ZPI6, AIM1_ARATH ;  Q7U004, ECH12_MYCBO;  P53526, ECH12_MYCLE;
DR   O53163, ECH12_MYCTU;  P64019, ECH14_MYCBO;  P64018, ECH14_MYCTU;
DR   A0QJH8, ECH17_MYCA1;  Q7TXE1, ECH17_MYCBO;  A1KN36, ECH17_MYCBP;
DR   Q73VC7, ECH17_MYCPA;  A5U753, ECH17_MYCTA;  O53286, ECH17_MYCTU;
DR   Q7U2S5, ECH1_MYCBO ;  P96807, ECH1_MYCTU ;  P64015, ECHA6_MYCBO;
DR   Q50130, ECHA6_MYCLE;  P64014, ECHA6_MYCTU;  P64017, ECHA8_MYCBO;
DR   O07137, ECHA8_MYCLE;  P64016, ECHA8_MYCTU;  P40939, ECHA_HUMAN ;
DR   Q8BMS1, ECHA_MOUSE ;  Q29554, ECHA_PIG   ;  Q64428, ECHA_RAT   ;
DR   Q52995, ECHH_RHIME ;  P24162, ECHH_RHOCB ;  Q58DM8, ECHM_BOVIN ;
DR   P34559, ECHM_CAEEL ;  Q1ZXF1, ECHM_DICDI ;  P30084, ECHM_HUMAN ;
DR   Q8BH95, ECHM_MOUSE ;  Q5R646, ECHM_PONAB ;  P14604, ECHM_RAT   ;
DR   P55100, ECHP_CAVPO ;  Q6NYL3, ECHP_DANRE ;  Q08426, ECHP_HUMAN ;
DR   Q9DBM2, ECHP_MOUSE ;  Q5R5M8, ECHP_PONAB ;  P07896, ECHP_RAT   ;
DR   Q4UL32, FAD3_RICFE ;  Q9ZCZ1, FAD3_RICPR ;  Q68WH7, FAD3_RICTY ;
DR   Q6FF68, FADB_ACIAD ;  B7H1I0, FADB_ACIB3 ;  B7I3P1, FADB_ACIB5 ;
DR   B2I2J9, FADB_ACIBC ;  B0VLX4, FADB_ACIBS ;  B0VE45, FADB_ACIBY ;
DR   A0KEL1, FADB_AERHH ;  A4STF2, FADB_AERS4 ;  B6EGU2, FADB_ALISL ;
DR   P94549, FADB_BACSU ;  A8ACZ4, FADB_CITK8 ;  Q489W3, FADB_COLP3 ;
DR   A7ZU51, FADB_ECO24 ;  B7UNH4, FADB_ECO27 ;  B7MHD1, FADB_ECO45 ;
DR   B7L9A7, FADB_ECO55 ;  Q8X8I2, FADB_ECO57 ;  B5YY93, FADB_ECO5E ;
DR   B7NV20, FADB_ECO7I ;  B7N2F2, FADB_ECO81 ;  B7M649, FADB_ECO8A ;
DR   C5A020, FADB_ECOBW ;  B1XAK8, FADB_ECODH ;  A8A6V1, FADB_ECOHS ;
DR   Q0TAL0, FADB_ECOL5 ;  Q8FBI2, FADB_ECOL6 ;  B1IW61, FADB_ECOLC ;
DR   P21177, FADB_ECOLI ;  B7NFE7, FADB_ECOLU ;  B6I4I6, FADB_ECOSE ;
DR   B1LM32, FADB_ECOSM ;  Q1R466, FADB_ECOUT ;  A4WFX4, FADB_ENT38 ;
DR   Q9F0Y7, FADB_ENTCL ;  A7MQP0, FADB_ENTS8 ;  Q6DAP5, FADB_ERWCT ;
DR   B7LTY9, FADB_ESCF3 ;  Q5QXH7, FADB_IDILO ;  B5XYH0, FADB_KLEP3 ;
DR   A6TGM4, FADB_KLEP7 ;  Q7MZ92, FADB_PHOLL ;  Q6LW06, FADB_PHOPR ;
DR   Q48GW3, FADB_PSE14 ;  A6V382, FADB_PSEA7 ;  B7UYR6, FADB_PSEA8 ;
DR   Q02PH8, FADB_PSEAB ;  Q9HZJ2, FADB_PSEAE ;  Q1I7D4, FADB_PSEE4 ;
DR   Q4KFC4, FADB_PSEF5 ;  P28793, FADB_PSEFR ;  C3K613, FADB_PSEFS ;
DR   A4XSM8, FADB_PSEMY ;  Q93Q12, FADB_PSEOL ;  A5W6H0, FADB_PSEP1 ;
DR   Q3K9D8, FADB_PSEPF ;  B0KH74, FADB_PSEPG ;  Q88L02, FADB_PSEPK ;
DR   Q9AHY3, FADB_PSEPU ;  B1J5A5, FADB_PSEPW ;  Q87ZB2, FADB_PSESM ;
DR   Q4ZRA0, FADB_PSEU2 ;  A4VKA3, FADB_PSEU5 ;  Q4FQC6, FADB_PSYA2 ;
DR   Q1Q8J9, FADB_PSYCK ;  A5WH99, FADB_PSYWF ;  B5EZW0, FADB_SALA4 ;
DR   Q57HM6, FADB_SALCH ;  B5QW85, FADB_SALEP ;  B5RFL6, FADB_SALG2 ;
DR   B4SZ85, FADB_SALNS ;  Q5PKQ2, FADB_SALPA ;  A9MYB0, FADB_SALPB ;
DR   B5BIZ0, FADB_SALPK ;  B4TNZ1, FADB_SALSV ;  Q8Z3C6, FADB_SALTI ;
DR   Q9L6L5, FADB_SALTY ;  A8G8D1, FADB_SERP5 ;  A1S1I8, FADB_SHEAM ;
DR   B8E3R3, FADB_SHEB2 ;  A3CYJ4, FADB_SHEB5 ;  A6WHA0, FADB_SHEB8 ;
DR   A9KU91, FADB_SHEB9 ;  Q08A39, FADB_SHEFN ;  B0TLB9, FADB_SHEHH ;
DR   A3Q8U4, FADB_SHELP ;  Q8EKR9, FADB_SHEON ;  A8GYG0, FADB_SHEPA ;
DR   A4Y1B6, FADB_SHEPC ;  B8CH91, FADB_SHEPW ;  A0KR50, FADB_SHESA ;
DR   A8FP63, FADB_SHESH ;  Q0HPB7, FADB_SHESM ;  Q0I0T3, FADB_SHESR ;
DR   A1RDW6, FADB_SHESW ;  B1KCZ3, FADB_SHEWM ;  B2TVJ5, FADB_SHIB3 ;
DR   Q32A21, FADB_SHIDS ;  Q0SZ36, FADB_SHIF8 ;  Q83PG1, FADB_SHIFL ;
DR   Q3YVC1, FADB_SHISS ;  A5F465, FADB_VIBC3 ;  Q9KNI1, FADB_VIBCH ;
DR   C3LSI3, FADB_VIBCM ;  Q5E8X6, FADB_VIBF1 ;  B5FEW8, FADB_VIBFM ;
DR   A7N1D2, FADB_VIBHB ;  Q87TN9, FADB_VIBPA ;  B7VGL4, FADB_VIBSL ;
DR   Q8DDK6, FADB_VIBVU ;  Q7MQH9, FADB_VIBVY ;  A1JIG4, FADB_YERE8 ;
DR   A7FDF2, FADB_YERP3 ;  Q1C2C4, FADB_YERPA ;  B2K0Z6, FADB_YERPB ;
DR   Q8ZAN0, FADB_YERPE ;  A9R754, FADB_YERPG ;  Q1CN99, FADB_YERPN ;
DR   A4TR27, FADB_YERPP ;  Q66FR8, FADB_YERPS ;  B1JP63, FADB_YERPY ;
DR   A8ADP2, FADJ_CITK8 ;  A7ZPF8, FADJ_ECO24 ;  B7UFZ8, FADJ_ECO27 ;
DR   B7MGV7, FADJ_ECO45 ;  B7LBJ5, FADJ_ECO55 ;  Q8XCP2, FADJ_ECO57 ;
DR   B5YXY4, FADJ_ECO5E ;  B7NP24, FADJ_ECO7I ;  B7MY16, FADJ_ECO81 ;
DR   B7M6M2, FADJ_ECO8A ;  C4ZVN2, FADJ_ECOBW ;  B1X9L4, FADJ_ECODH ;
DR   A8A2L0, FADJ_ECOHS ;  A1ADI8, FADJ_ECOK1 ;  Q0TFA6, FADJ_ECOL5 ;
DR   Q8FFG4, FADJ_ECOL6 ;  B1IXA5, FADJ_ECOLC ;  P77399, FADJ_ECOLI ;
DR   B7N5V2, FADJ_ECOLU ;  B6I6Q4, FADJ_ECOSE ;  B1LME7, FADJ_ECOSM ;
DR   Q1R972, FADJ_ECOUT ;  A4WCW6, FADJ_ENT38 ;  A7MH81, FADJ_ENTS8 ;
DR   Q6D2L7, FADJ_ERWCT ;  B7LLD0, FADJ_ESCF3 ;  Q5QXM1, FADJ_IDILO ;
DR   B5XVW2, FADJ_KLEP3 ;  A6TC19, FADJ_KLEP7 ;  C6DAL7, FADJ_PECCP ;
DR   Q7N288, FADJ_PHOLL ;  Q6LTK3, FADJ_PHOPR ;  B5EZR9, FADJ_SALA4 ;
DR   Q57LW6, FADJ_SALCH ;  B5FPN1, FADJ_SALDC ;  B5R3R9, FADJ_SALEP ;
DR   B5RCL3, FADJ_SALG2 ;  B4TCA8, FADJ_SALHS ;  B4SZR0, FADJ_SALNS ;
DR   Q5PCX6, FADJ_SALPA ;  A9N453, FADJ_SALPB ;  B5BBA1, FADJ_SALPK ;
DR   B4TQC2, FADJ_SALSV ;  Q8Z4Z0, FADJ_SALTI ;  Q8ZNA7, FADJ_SALTY ;
DR   A8GH86, FADJ_SERP5 ;  A1S7L6, FADJ_SHEAM ;  A3D684, FADJ_SHEB5 ;
DR   A6WQ25, FADJ_SHEB8 ;  Q07ZP8, FADJ_SHEFN ;  B0TL21, FADJ_SHEHH ;
DR   A3QFP3, FADJ_SHELP ;  Q8ECP7, FADJ_SHEON ;  A4Y897, FADJ_SHEPC ;
DR   A0KV76, FADJ_SHESA ;  Q0HKD1, FADJ_SHESM ;  Q0HWN3, FADJ_SHESR ;
DR   A1RI92, FADJ_SHESW ;  B2TWV4, FADJ_SHIB3 ;  Q31YB7, FADJ_SHIBS ;
DR   Q32DJ4, FADJ_SHIDS ;  Q0T2E6, FADJ_SHIF8 ;  Q83QQ0, FADJ_SHIFL ;
DR   Q3YZM2, FADJ_SHISS ;  A5F2P2, FADJ_VIBC3 ;  Q9KT58, FADJ_VIBCH ;
DR   Q5E3U1, FADJ_VIBF1 ;  A7MS61, FADJ_VIBHB ;  Q87MM3, FADJ_VIBPA ;
DR   Q8DB47, FADJ_VIBVU ;  Q7MIS5, FADJ_VIBVY ;  A1JK30, FADJ_YERE8 ;
DR   A7FGK1, FADJ_YERP3 ;  Q1C660, FADJ_YERPA ;  Q8ZD45, FADJ_YERPE ;
DR   Q1CHK2, FADJ_YERPN ;  A4TM82, FADJ_YERPP ;  Q668V1, FADJ_YERPS ;
DR   Q9ZPI5, MFP2_ARATH ;  O49809, MFPA_BRANA ;  Q39659, MFPA_CUCSA ;
DR   Q8W1L6, MFP_ORYSJ  ;  P76082, PAAF_ECOLI ;  P77467, PAAG_ECOLI ;
//
ID   4.2.1.18
DE   Methylglutaconyl-CoA hydratase.
CA   (S)-3-hydroxy-3-methylglutaryl-CoA = trans-3-methylglutaconyl-CoA +
CA   H(2)O.
PR   PROSITE; PDOC00150;
DR   Q54HG7, AUHM_DICDI ;  Q13825, AUHM_HUMAN ;  Q9JLZ3, AUHM_MOUSE ;
//
ID   4.2.1.19
DE   Imidazoleglycerol-phosphate dehydratase.
CA   D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-
CA   oxopropyl phosphate + H(2)O.
PR   PROSITE; PDOC00738;
DR   P34047, HIS7A_ARATH;  O23346, HIS7B_ARATH;  A1TKZ1, HIS7_ACIAC ;
DR   Q6F7A8, HIS7_ACIAD ;  Q1IKB4, HIS7_ACIBL ;  B0VPC2, HIS7_ACIBS ;
DR   B0V8S1, HIS7_ACIBY ;  A0LTS3, HIS7_ACIC1 ;  A5FYE1, HIS7_ACICJ ;
DR   B9MDV5, HIS7_ACIET ;  B7JA16, HIS7_ACIF2 ;  B5EQE9, HIS7_ACIF5 ;
DR   A1W432, HIS7_ACISJ ;  A3N3W1, HIS7_ACTP2 ;  B3GZG9, HIS7_ACTP7 ;
DR   B0BU51, HIS7_ACTPJ ;  A6VM11, HIS7_ACTSZ ;  Q8UJ89, HIS7_AGRT5 ;
DR   B2UL23, HIS7_AKKM8 ;  Q0VM69, HIS7_ALCBS ;  Q0A5D0, HIS7_ALHEH ;
DR   A6TKT3, HIS7_ALKMQ ;  Q8KY27, HIS7_AMIAM ;  B8JDL0, HIS7_ANAD2 ;
DR   Q2INV5, HIS7_ANADE ;  A7H8C1, HIS7_ANADF ;  B4UDJ7, HIS7_ANASK ;
DR   B9MJR6, HIS7_ANATD ;  O66455, HIS7_AQUAE ;  A8ETG3, HIS7_ARCB4 ;
DR   O29277, HIS7_ARCFU ;  Q5P792, HIS7_AROAE ;  A1R559, HIS7_ARTAT ;
DR   B8HGA0, HIS7_ARTCA ;  A0JUZ5, HIS7_ARTS2 ;  Q75B47, HIS7_ASHGO ;
DR   P18787, HIS7_AZOBR ;  A8HYU9, HIS7_AZOC5 ;  A1KAV7, HIS7_AZOSB ;
DR   C1DJC9, HIS7_AZOVD ;  A7Z965, HIS7_BACA2 ;  C3P503, HIS7_BACAA ;
DR   C3L9Q0, HIS7_BACAC ;  A0RBL9, HIS7_BACAH ;  Q81T61, HIS7_BACAN ;
DR   B7JFZ2, HIS7_BACC0 ;  P61658, HIS7_BACC1 ;  B7INA0, HIS7_BACC2 ;
DR   C1EMQ4, HIS7_BACC3 ;  B7HHG2, HIS7_BACC4 ;  B7HKD1, HIS7_BACC7 ;
DR   A7GMU7, HIS7_BACCN ;  B9IUZ7, HIS7_BACCQ ;  Q81G05, HIS7_BACCR ;
DR   Q63DX1, HIS7_BACCZ ;  Q5LB00, HIS7_BACFN ;  Q64RE9, HIS7_BACFR ;
DR   Q9K6Z3, HIS7_BACHD ;  Q6HLE6, HIS7_BACHK ;  Q65EG0, HIS7_BACLD ;
DR   A8FHR2, HIS7_BACP2 ;  Q5WDH9, HIS7_BACSK ;  O34683, HIS7_BACSU ;
DR   Q8ABA7, HIS7_BACTN ;  A9VLH4, HIS7_BACWK ;  Q1LT69, HIS7_BAUCH ;
DR   B2ICL6, HIS7_BEII9 ;  B8DSW4, HIS7_BIFA0 ;  A1A2H5, HIS7_BIFAA ;
DR   B3DQA1, HIS7_BIFLD ;  Q8G4S7, HIS7_BIFLO ;  B7GQ48, HIS7_BIFLS ;
DR   Q7VQW8, HIS7_BLOFL ;  Q2KTT4, HIS7_BORA1 ;  Q7WDY2, HIS7_BORBR ;
DR   Q7W2Y2, HIS7_BORPA ;  A9HWC8, HIS7_BORPD ;  Q7VSY9, HIS7_BORPE ;
DR   Q89WM8, HIS7_BRAJA ;  A5E8F1, HIS7_BRASB ;  A4YJV1, HIS7_BRASO ;
DR   B2S980, HIS7_BRUA1 ;  Q2YQZ2, HIS7_BRUA2 ;  Q57AH7, HIS7_BRUAB ;
DR   A9M9R5, HIS7_BRUC2 ;  C0RFW9, HIS7_BRUMB ;  P64366, HIS7_BRUME ;
DR   A5VT39, HIS7_BRUO2 ;  B0CJI2, HIS7_BRUSI ;  P64367, HIS7_BRUSU ;
DR   B8D8Q4, HIS7_BUCA5 ;  P57203, HIS7_BUCAI ;  Q9ZHE4, HIS7_BUCAP ;
DR   B8D708, HIS7_BUCAT ;  P59454, HIS7_BUCBP ;  B1YRV7, HIS7_BURA4 ;
DR   Q1BS27, HIS7_BURCA ;  B1JUA1, HIS7_BURCC ;  A0K3V4, HIS7_BURCH ;
DR   B4E637, HIS7_BURCJ ;  Q0BIW8, HIS7_BURCM ;  Q845V1, HIS7_BURM1 ;
DR   A3MPU8, HIS7_BURM7 ;  A2S750, HIS7_BURM9 ;  Q62GE1, HIS7_BURMA ;
DR   A1V8H1, HIS7_BURMS ;  A3P031, HIS7_BURP0 ;  Q3JMZ8, HIS7_BURP1 ;
DR   A3NE97, HIS7_BURP6 ;  B2JHY3, HIS7_BURP8 ;  B2SZ63, HIS7_BURPP ;
DR   Q63Q88, HIS7_BURPS ;  Q39K89, HIS7_BURS3 ;  Q2SUA4, HIS7_BURTA ;
DR   A4JAW5, HIS7_BURVG ;  Q13TQ6, HIS7_BURXL ;  A8M909, HIS7_CALMQ ;
DR   A4XL23, HIS7_CALS8 ;  A7ZEG5, HIS7_CAMC1 ;  A7GXG2, HIS7_CAMC5 ;
DR   A0RQ64, HIS7_CAMFF ;  A7I064, HIS7_CAMHC ;  A8FNR1, HIS7_CAMJ8 ;
DR   A7H5U9, HIS7_CAMJD ;  Q9PM76, HIS7_CAMJE ;  A1W1K1, HIS7_CAMJJ ;
DR   Q5HSJ2, HIS7_CAMJR ;  P56090, HIS7_CANAL ;  Q12578, HIS7_CANGA ;
DR   Q3AD51, HIS7_CARHZ ;  B8GW12, HIS7_CAUCN ;  Q9A232, HIS7_CAUCR ;
DR   B0T7A1, HIS7_CAUSK ;  B3PGA1, HIS7_CELJU ;  A0RZ75, HIS7_CENSY ;
DR   A9WDZ1, HIS7_CHLAA ;  B8G451, HIS7_CHLAD ;  Q3AQD7, HIS7_CHLCH ;
DR   B3EDX3, HIS7_CHLL2 ;  B3QMG8, HIS7_CHLP8 ;  B3EKC2, HIS7_CHLPB ;
DR   A1BF00, HIS7_CHLPD ;  B3QTX2, HIS7_CHLT3 ;  Q8KEF4, HIS7_CHLTE ;
DR   Q1R077, HIS7_CHRSD ;  Q7P0F3, HIS7_CHRVO ;  A5CSK8, HIS7_CLAM3 ;
DR   B0RHB5, HIS7_CLAMS ;  Q97KI1, HIS7_CLOAB ;  A7FU78, HIS7_CLOB1 ;
DR   C3KVX2, HIS7_CLOB6 ;  A6LT19, HIS7_CLOB8 ;  B2UX23, HIS7_CLOBA ;
DR   A5I242, HIS7_CLOBH ;  C1FN38, HIS7_CLOBJ ;  B1ILA6, HIS7_CLOBK ;
DR   A7GDQ3, HIS7_CLOBL ;  B8I5V2, HIS7_CLOCE ;  Q18C69, HIS7_CLOD6 ;
DR   B9E169, HIS7_CLOK1 ;  A5N7Q8, HIS7_CLOK5 ;  A0PXP6, HIS7_CLONN ;
DR   A9KNX4, HIS7_CLOPH ;  A3DJF3, HIS7_CLOTH ;  Q47XB6, HIS7_COLP3 ;
DR   P60884, HIS7_CORDI ;  Q8FNZ2, HIS7_COREF ;  A4QFG5, HIS7_CORGB ;
DR   Q9KJU3, HIS7_CORGL ;  Q4JW57, HIS7_CORJK ;  B1VH93, HIS7_CORU7 ;
DR   P0CO23, HIS7_CRYNB ;  P0CO22, HIS7_CRYNJ ;  Q0K689, HIS7_CUPNH ;
DR   Q46WL4, HIS7_CUPPJ ;  B3R798, HIS7_CUPTR ;  O94126, HIS7_CYBJA ;
DR   Q47AM0, HIS7_DECAR ;  Q3Z880, HIS7_DEHE1 ;  A5FR28, HIS7_DEHSB ;
DR   Q3ZXL9, HIS7_DEHSC ;  C1D1S1, HIS7_DEIDV ;  Q1IZQ5, HIS7_DEIGD ;
DR   Q9RX91, HIS7_DEIRA ;  C6BSE1, HIS7_DESAD ;  B1I559, HIS7_DESAP ;
DR   Q311Y0, HIS7_DESDG ;  Q24QJ2, HIS7_DESHY ;  C4XSN6, HIS7_DESMR ;
DR   A8ZUC7, HIS7_DESOH ;  Q6ANL7, HIS7_DESPS ;  A4J710, HIS7_DESRM ;
DR   P61659, HIS7_DESVH ;  B8DNB6, HIS7_DESVM ;  A1VEV3, HIS7_DESVV ;
DR   B5YE87, HIS7_DICT6 ;  B8E2C5, HIS7_DICTD ;  A8LQZ6, HIS7_DINSH ;
DR   Q9S5G5, HIS7_ECO57 ;  Q8FG50, HIS7_ECOL6 ;  P06987, HIS7_ECOLI ;
DR   Q6D409, HIS7_ERWCT ;  Q2N8I5, HIS7_ERYLH ;  C4L173, HIS7_EXISA ;
DR   Q2J8L0, HIS7_FRASC ;  A8LGQ5, HIS7_FRASN ;  B5EDR7, HIS7_GEOBB ;
DR   Q5KVC7, HIS7_GEOKA ;  B3E4Y5, HIS7_GEOLS ;  Q39YP5, HIS7_GEOMG ;
DR   B9M0L7, HIS7_GEOSF ;  P60885, HIS7_GEOSL ;  C6E7F7, HIS7_GEOSM ;
DR   C5D7P1, HIS7_GEOSW ;  A4ISR5, HIS7_GEOTN ;  A5G8T2, HIS7_GEOUR ;
DR   Q7NMJ6, HIS7_GLOVI ;  A9GZY1, HIS7_GLUDA ;  Q5FTN7, HIS7_GLUOX ;
DR   Q0BPW9, HIS7_GRABC ;  Q4QN72, HIS7_HAEI8 ;  A5UA18, HIS7_HAEIE ;
DR   A5UGY3, HIS7_HAEIG ;  P44327, HIS7_HAEIN ;  Q2SMB5, HIS7_HAHCH ;
DR   A1WW08, HIS7_HALHL ;  Q5UZF0, HIS7_HALMA ;  B0R7J1, HIS7_HALS3 ;
DR   Q9HN13, HIS7_HALSA ;  Q18DL1, HIS7_HALWD ;  Q7VGJ6, HIS7_HELHP ;
DR   B0TDN0, HIS7_HELMI ;  A4G9I9, HIS7_HERAR ;  B4U7F2, HIS7_HYDS0 ;
DR   Q0C636, HIS7_HYPNA ;  A6T379, HIS7_JANMA ;  Q28NK7, HIS7_JANSC ;
DR   A6WCV0, HIS7_KINRD ;  A6TBC5, HIS7_KLEP7 ;  Q6CLR6, HIS7_KLULA ;
DR   Q6JV40, HIS7_KLUMA ;  Q039B2, HIS7_LACC3 ;  B3WED4, HIS7_LACCB ;
DR   B2GBR2, HIS7_LACF3 ;  Q02134, HIS7_LACLA ;  A2RKS1, HIS7_LACLM ;
DR   Q02YW7, HIS7_LACLS ;  Q88UE0, HIS7_LACPL ;  C1DAK1, HIS7_LARHH ;
DR   Q5X5X1, HIS7_LEGPA ;  Q5ZW89, HIS7_LEGPH ;  Q5WX93, HIS7_LEGPL ;
DR   Q6AE13, HIS7_LEIXX ;  B0SDS4, HIS7_LEPBA ;  Q04W74, HIS7_LEPBJ ;
DR   Q056S6, HIS7_LEPBL ;  B0SLU7, HIS7_LEPBP ;  P61660, HIS7_LEPIC ;
DR   Q8F9R6, HIS7_LEPIN ;  Q03VX7, HIS7_LEUMM ;  Q92E85, HIS7_LISIN ;
DR   C1L0J5, HIS7_LISMC ;  Q722Y4, HIS7_LISMF ;  B8DA59, HIS7_LISMH ;
DR   Q8Y9G2, HIS7_LISMO ;  A0AG18, HIS7_LISW6 ;  O42621, HIS7_MAGO7 ;
DR   Q2VYI7, HIS7_MAGSA ;  A0LBT6, HIS7_MAGSM ;  Q65RB3, HIS7_MANSM ;
DR   A1U5H8, HIS7_MARAV ;  A6VTA8, HIS7_MARMS ;  Q11CL1, HIS7_MESSB ;
DR   A6UTB1, HIS7_META3 ;  P58878, HIS7_METAC ;  A7I774, HIS7_METB6 ;
DR   Q46CW9, HIS7_METBF ;  Q12WC5, HIS7_METBU ;  B7KPM4, HIS7_METC4 ;
DR   Q603K0, HIS7_METCA ;  A9W5T6, HIS7_METEP ;  Q1H4R5, HIS7_METFK ;
DR   Q2FN13, HIS7_METHJ ;  Q58109, HIS7_METJA ;  P58879, HIS7_METKA ;
DR   A4FYS8, HIS7_METM5 ;  A9A756, HIS7_METM6 ;  A6VJJ9, HIS7_METM7 ;
DR   Q8PWS1, HIS7_METMA ;  A3CTR8, HIS7_METMJ ;  P60888, HIS7_METMP ;
DR   B1ZAD1, HIS7_METPB ;  B8GJY3, HIS7_METPE ;  A2SE06, HIS7_METPP ;
DR   B1LU98, HIS7_METRJ ;  A5UMI3, HIS7_METS3 ;  A4YI33, HIS7_METS5 ;
DR   B8EM89, HIS7_METSB ;  Q2NHQ1, HIS7_METST ;  Q50504, HIS7_METTH ;
DR   A6UN45, HIS7_METVS ;  B0JJ52, HIS7_MICAN ;  Q2RGV9, HIS7_MOOTA ;
DR   A0QHI0, HIS7_MYCA1 ;  P64369, HIS7_MYCBO ;  A1KJ17, HIS7_MYCBP ;
DR   C1ANM3, HIS7_MYCBT ;  A4T9M6, HIS7_MYCGI ;  B8ZRB1, HIS7_MYCLB ;
DR   Q9X7B9, HIS7_MYCLE ;  B2HQA4, HIS7_MYCMM ;  P60886, HIS7_MYCPA ;
DR   A0QX83, HIS7_MYCS2 ;  A3Q129, HIS7_MYCSJ ;  A1UHK6, HIS7_MYCSK ;
DR   Q1B7G6, HIS7_MYCSS ;  A5U2V7, HIS7_MYCTA ;  P64368, HIS7_MYCTU ;
DR   A0PP16, HIS7_MYCUA ;  A1T8W3, HIS7_MYCVP ;  Q3IRM3, HIS7_NATPD ;
DR   B9LAD4, HIS7_NAUPA ;  Q5F7D6, HIS7_NEIG1 ;  A9M186, HIS7_NEIM0 ;
DR   P64370, HIS7_NEIMA ;  P64371, HIS7_NEIMB ;  A1KV07, HIS7_NEIMF ;
DR   Q9HEG3, HIS7_NEUCR ;  Q0AEU4, HIS7_NITEC ;  Q82WM4, HIS7_NITEU ;
DR   Q1QRX4, HIS7_NITHX ;  Q2YAU7, HIS7_NITMU ;  Q3J6Q4, HIS7_NITOC ;
DR   A6Q330, HIS7_NITSB ;  Q3SWE7, HIS7_NITWN ;  Q5YYP8, HIS7_NOCFA ;
DR   A1SL60, HIS7_NOCSJ ;  Q05068, HIS7_NOSS1 ;  Q2G9M2, HIS7_NOVAD ;
DR   Q8ESR9, HIS7_OCEIH ;  A6WX56, HIS7_OCHA4 ;  B6JAL6, HIS7_OLICO ;
DR   A1B384, HIS7_PARDP ;  A7HSH4, HIS7_PARL1 ;  P57920, HIS7_PASMU ;
DR   Q43072, HIS7_PEA   ;  Q3A134, HIS7_PELCD ;  Q3B4Y6, HIS7_PELLD ;
DR   B4SD35, HIS7_PELPB ;  A1ATG7, HIS7_PELPD ;  A5CZ77, HIS7_PELTS ;
DR   Q4FNT4, HIS7_PELUB ;  C0QUG8, HIS7_PERMH ;  O94153, HIS7_PHARH ;
DR   B4RBJ4, HIS7_PHEZH ;  Q7N6I2, HIS7_PHOLL ;  P62455, HIS7_PHOPR ;
DR   P28624, HIS7_PHYPR ;  Q92447, HIS7_PICPA ;  Q9C1D4, HIS7_PICST ;
DR   A1VK39, HIS7_POLNA ;  B1XSV0, HIS7_POLNS ;  Q12FD0, HIS7_POLSJ ;
DR   A4SV17, HIS7_POLSQ ;  B4S729, HIS7_PROA2 ;  Q6A8L3, HIS7_PROAC ;
DR   A3PB03, HIS7_PROM0 ;  A2C0B5, HIS7_PROM1 ;  A8G2U2, HIS7_PROM2 ;
DR   A2CCN3, HIS7_PROM3 ;  A9BDS9, HIS7_PROM4 ;  A2BUR2, HIS7_PROM5 ;
DR   Q31CQ1, HIS7_PROM9 ;  Q7VDQ5, HIS7_PROMA ;  Q7V4R6, HIS7_PROMM ;
DR   Q7V314, HIS7_PROMP ;  A2BP81, HIS7_PROMS ;  Q46H93, HIS7_PROMT ;
DR   A4SF66, HIS7_PROVI ;  Q48C77, HIS7_PSE14 ;  Q15RU7, HIS7_PSEA6 ;
DR   A6VDR3, HIS7_PSEA7 ;  B7V3N7, HIS7_PSEA8 ;  Q02EM2, HIS7_PSEAB ;
DR   Q9HU41, HIS7_PSEAE ;  Q1I3G4, HIS7_PSEE4 ;  Q4KJS8, HIS7_PSEF5 ;
DR   C3K6U9, HIS7_PSEFS ;  A4Y087, HIS7_PSEMY ;  A5VX72, HIS7_PSEP1 ;
DR   Q3KJI9, HIS7_PSEPF ;  B0KI41, HIS7_PSEPG ;  Q88R45, HIS7_PSEPK ;
DR   B1JED5, HIS7_PSEPW ;  Q87UG0, HIS7_PSESM ;  Q4ZLP8, HIS7_PSEU2 ;
DR   A4VRW2, HIS7_PSEU5 ;  A5WBH9, HIS7_PSYWF ;  Q8ZY15, HIS7_PYRAE ;
DR   A4WHB8, HIS7_PYRAR ;  A3MSG0, HIS7_PYRCJ ;  P58880, HIS7_PYRFU ;
DR   Q1LIA8, HIS7_RALME ;  B2UEE9, HIS7_RALPJ ;  Q8XV81, HIS7_RALSO ;
DR   A9WQ57, HIS7_RENSM ;  B3PWI5, HIS7_RHIE6 ;  Q2KE56, HIS7_RHIEC ;
DR   Q1MNB6, HIS7_RHIL3 ;  Q98CT7, HIS7_RHILO ;  B5ZV97, HIS7_RHILW ;
DR   Q92TB0, HIS7_RHIME ;  C3MBC5, HIS7_RHISN ;  Q7UNC2, HIS7_RHOBA ;
DR   C1A0M3, HIS7_RHOE4 ;  Q21U94, HIS7_RHOFD ;  C1ATZ4, HIS7_RHOOB ;
DR   Q2J344, HIS7_RHOP2 ;  Q07UQ5, HIS7_RHOP5 ;  P60887, HIS7_RHOPA ;
DR   Q21CK7, HIS7_RHOPB ;  Q13E36, HIS7_RHOPS ;  B3Q8C2, HIS7_RHOPT ;
DR   Q2RNA4, HIS7_RHORT ;  A3PI66, HIS7_RHOS1 ;  O33564, HIS7_RHOS4 ;
DR   A4WUS5, HIS7_RHOS5 ;  B9KPD2, HIS7_RHOSK ;  Q0SHY0, HIS7_RHOSR ;
DR   A7NQZ5, HIS7_ROSCS ;  Q162Q6, HIS7_ROSDO ;  A5USC4, HIS7_ROSS1 ;
DR   Q1AX09, HIS7_RUBXD ;  Q21NH8, HIS7_SACD2 ;  A4FLN6, HIS7_SACEN ;
DR   Q02986, HIS7_SACKL ;  A8LX62, HIS7_SALAI ;  Q5PDP5, HIS7_SALPA ;
DR   Q2S2A1, HIS7_SALRD ;  Q8Z5J8, HIS7_SALTI ;  A4X9Q4, HIS7_SALTO ;
DR   P10368, HIS7_SALTY ;  P40374, HIS7_SCHPO ;  Q8EFB3, HIS7_SHEON ;
DR   Q83R05, HIS7_SHIFL ;  Q5LU92, HIS7_SILPO ;  Q1GF01, HIS7_SILST ;
DR   A6UEK7, HIS7_SINMW ;  Q2NTX3, HIS7_SODGM ;  Q01ZU4, HIS7_SOLUE ;
DR   Q1GNC0, HIS7_SPHAL ;  A5V9V7, HIS7_SPHWW ;  A7X766, HIS7_STAA1 ;
DR   A6U561, HIS7_STAA2 ;  Q2FDI5, HIS7_STAA3 ;  Q2FUU0, HIS7_STAA8 ;
DR   A5IWA3, HIS7_STAA9 ;  Q2YZ91, HIS7_STAAB ;  Q5HCM1, HIS7_STAAC ;
DR   A6QKG4, HIS7_STAAE ;  P64372, HIS7_STAAM ;  P64373, HIS7_STAAN ;
DR   Q6GDC8, HIS7_STAAR ;  Q6G5Z9, HIS7_STAAS ;  A8Z5H6, HIS7_STAAT ;
DR   P64374, HIS7_STAAW ;  B9DQ86, HIS7_STACT ;  Q5HKN9, HIS7_STAEQ ;
DR   Q8CQ94, HIS7_STAES ;  Q4A046, HIS7_STAS1 ;  Q82AA4, HIS7_STRAW ;
DR   P16247, HIS7_STRCO ;  A8AY27, HIS7_STRGC ;  B1W0M1, HIS7_STRGG ;
DR   B4STN9, HIS7_STRM5 ;  B2FPM1, HIS7_STRMK ;  Q8DTQ9, HIS7_STRMU ;
DR   A3CNT3, HIS7_STRSV ;  Q03K79, HIS7_STRTD ;  Q4J8J1, HIS7_SULAC ;
DR   Q30RM3, HIS7_SULDN ;  C3N6A7, HIS7_SULIA ;  C4KHS1, HIS7_SULIK ;
DR   C3MQI6, HIS7_SULIL ;  C3MW64, HIS7_SULIM ;  C3NGY0, HIS7_SULIN ;
DR   C3NER4, HIS7_SULIY ;  A6Q9M2, HIS7_SULNB ;  O33773, HIS7_SULSO ;
DR   Q970Z1, HIS7_SULTO ;  Q67KH7, HIS7_SYMTH ;  Q2LVF5, HIS7_SYNAS ;
DR   Q31S12, HIS7_SYNE7 ;  A0LQG8, HIS7_SYNFM ;  Q2JRL0, HIS7_SYNJA ;
DR   Q2JNK3, HIS7_SYNJB ;  Q5N2A1, HIS7_SYNP6 ;  A5GID0, HIS7_SYNPW ;
DR   Q7U9M8, HIS7_SYNPX ;  A5GWD4, HIS7_SYNR3 ;  Q0IDH6, HIS7_SYNS3 ;
DR   Q3B0A6, HIS7_SYNS9 ;  Q3AN36, HIS7_SYNSC ;  Q0AW39, HIS7_SYNWW ;
DR   P48054, HIS7_SYNY3 ;  C5BMF2, HIS7_TERTT ;  Q8DMI3, HIS7_THEEB ;
DR   Q47QS7, HIS7_THEFY ;  Q9X0C9, HIS7_THEMA ;  B9K9S0, HIS7_THENN ;
DR   A5INE3, HIS7_THEP1 ;  B0K736, HIS7_THEP3 ;  B0K626, HIS7_THEPX ;
DR   B1L870, HIS7_THESQ ;  P61661, HIS7_THET2 ;  Q5SL64, HIS7_THET8 ;
DR   P58877, HIS7_THETN ;  B5YKN8, HIS7_THEYD ;  Q31E67, HIS7_THICR ;
DR   Q3SEU5, HIS7_THIDA ;  B8GU29, HIS7_THISH ;  Q6XD66, HIS7_TORDE ;
DR   Q93DQ9, HIS7_TRIEI ;  P34041, HIS7_TRIHA ;  Q0W0J2, HIS7_UNCMA ;
DR   B1H0E9, HIS7_UNCTG ;  A1WR21, HIS7_VEREI ;  A5CVR1, HIS7_VESOH ;
DR   Q9KSX1, HIS7_VIBCH ;  Q87QK9, HIS7_VIBPA ;  Q8D8Q2, HIS7_VIBVU ;
DR   Q7MLS4, HIS7_VIBVY ;  P34048, HIS7_WHEAT ;  Q7M7V2, HIS7_WOLSU ;
DR   P58881, HIS7_XANAC ;  Q3BUF5, HIS7_XANC5 ;  Q4UU42, HIS7_XANC8 ;
DR   B0RSL6, HIS7_XANCB ;  P58882, HIS7_XANCP ;  Q2P3K1, HIS7_XANOM ;
DR   B2SKN6, HIS7_XANOP ;  Q5H0K9, HIS7_XANOR ;  A7IHP3, HIS7_XANP2 ;
DR   B2I5X9, HIS7_XYLF2 ;  Q9PBC7, HIS7_XYLFA ;  B0U3B1, HIS7_XYLFM ;
DR   Q87C31, HIS7_XYLFT ;  P06633, HIS7_YEAST ;  Q8ZFX7, HIS7_YERPE ;
DR   Q66C51, HIS7_YERPS ;  Q96UK2, HIS7_ZYGBA ;  Q9UVE1, HIS7_ZYGRC ;
DR   Q5NMD3, HIS7_ZYMMO ;
//
ID   4.2.1.20
DE   Tryptophan synthase.
AN   Indoleglycerol phosphate aldolase.
AN   L-tryptophan synthetase.
AN   Tryptophan desmolase.
AN   Tryptophan synthetase.
CA   L-serine + 1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan +
CA   glyceraldehyde 3-phosphate + H(2)O.
CF   Pyridoxal 5'-phosphate.
CC   -!- The alpha-subunit catalyzes the conversion of 1-C-(indol-3-
CC       yl)glycerol 3-phosphate to indole and glyceraldehyde 3-phosphate.
CC   -!- The indole then migrates to the beta-subunit where, with serine in
CC       the presence of pyridoxal 5'-phosphate, it is converted to
CC       tryptophan.
CC   -!- Also catalyzes the conversion of serine and indole into tryptophan
CC       and water, and of 1-C-(indol-3-yl)glycerol 3-phosphate into indole
CC       and glyceraldehyde phosphate (the latter reaction was listed formerly
CC       as EC 4.1.2.8).
CC   -!- In some organisms, this enzyme is part of a multifunctional protein,
CC       together with one or more other components of the system for the
CC       biosynthesis of tryptophan (EC 2.4.2.18, EC 4.1.1.48, EC 4.1.3.27 and
CC       EC 5.3.1.24).
PR   PROSITE; PDOC00151;
PR   PROSITE; PDOC00152;
DR   P25269, TRBP2_ARATH;  Q9TLW8, TRPA1_CYACA;  P34793, TRPA2_CYACA;
DR   B0C6F8, TRPA_ACAM1 ;  Q6FEE6, TRPA_ACIAD ;  B7GWQ5, TRPA_ACIB3 ;
DR   B7I8K2, TRPA_ACIB5 ;  B2HYJ0, TRPA_ACIBC ;  B0VRF8, TRPA_ACIBS ;
DR   A3M8N2, TRPA_ACIBT ;  B0V529, TRPA_ACIBY ;  A0LTT7, TRPA_ACIC1 ;
DR   A5FY58, TRPA_ACICJ ;  B9MDL9, TRPA_ACIET ;  B7J4S8, TRPA_ACIF2 ;
DR   B5EK17, TRPA_ACIF5 ;  A1WAT8, TRPA_ACISJ ;  A3MZI8, TRPA_ACTP2 ;
DR   B3GX47, TRPA_ACTP7 ;  B0BU73, TRPA_ACTPJ ;  A6VPE0, TRPA_ACTSZ ;
DR   A0KMD1, TRPA_AERHH ;  Q9Y8T3, TRPA_AERPE ;  A4SKT0, TRPA_AERS4 ;
DR   B9JG44, TRPA_AGRRK ;  Q8UJA9, TRPA_AGRT5 ;  B9JXV7, TRPA_AGRVS ;
DR   Q0VPJ0, TRPA_ALCBS ;  Q0A9A1, TRPA_ALHEH ;  B6EJA2, TRPA_ALISL ;
DR   A6TM77, TRPA_ALKMQ ;  B9MKC6, TRPA_ANATD ;  Q3MBD2, TRPA_ANAVT ;
DR   P31204, TRPA_ANTSP ;  O67502, TRPA_AQUAE ;  O28673, TRPA_ARCFU ;
DR   Q5P1I9, TRPA_AROAE ;  Q9LAG8, TRPA_AZOBR ;  A8HQ60, TRPA_AZOC5 ;
DR   B6YR34, TRPA_AZOPC ;  A1K4B0, TRPA_AZOSB ;  C1DH67, TRPA_AZOVD ;
DR   A7Z615, TRPA_BACA2 ;  C3P3U1, TRPA_BACAA ;  C3LAV7, TRPA_BACAC ;
DR   A0RB65, TRPA_BACAH ;  Q81TL7, TRPA_BACAN ;  B7JET1, TRPA_BACC0 ;
DR   Q73BQ6, TRPA_BACC1 ;  B7IM77, TRPA_BACC2 ;  C1ELF1, TRPA_BACC3 ;
DR   B7HH02, TRPA_BACC4 ;  B7I0F3, TRPA_BACC7 ;  Q81GG4, TRPA_BACCR ;
DR   Q63EC6, TRPA_BACCZ ;  Q5LBZ2, TRPA_BACFN ;  Q64SX3, TRPA_BACFR ;
DR   Q9KCA9, TRPA_BACHD ;  Q6HLU3, TRPA_BACHK ;  Q65I36, TRPA_BACLD ;
DR   Q8KZ93, TRPA_BACNA ;  A8FEJ7, TRPA_BACP2 ;  Q5WGS0, TRPA_BACSK ;
DR   P07601, TRPA_BACSU ;  Q8AAD8, TRPA_BACTN ;  A6L7N1, TRPA_BACV8 ;
DR   A9VJW3, TRPA_BACWK ;  B2IF46, TRPA_BEII9 ;  Q8G691, TRPA_BIFLO ;
DR   Q7VQZ9, TRPA_BLOFL ;  Q7WD05, TRPA_BORBR ;  Q7W5G9, TRPA_BORPA ;
DR   Q7VTF0, TRPA_BORPE ;  Q89WE4, TRPA_BRAJA ;  A4YJI5, TRPA_BRASO ;
DR   B2S9A3, TRPA_BRUA1 ;  Q2YQW7, TRPA_BRUA2 ;  Q57AF2, TRPA_BRUAB ;
DR   A9M9U0, TRPA_BRUC2 ;  C0RFZ2, TRPA_BRUMB ;  Q8YE59, TRPA_BRUME ;
DR   A5VT61, TRPA_BRUO2 ;  B0CJK6, TRPA_BRUSI ;  Q8FXY6, TRPA_BRUSU ;
DR   B8D970, TRPA_BUCA5 ;  P57365, TRPA_BUCAI ;  P42389, TRPA_BUCAP ;
DR   B8D7H4, TRPA_BUCAT ;  P59457, TRPA_BUCBP ;  O68429, TRPA_BUCDN ;
DR   Q9RQ33, TRPA_BUCMH ;  Q44604, TRPA_BUCSC ;  B1Z1P1, TRPA_BURA4 ;
DR   Q1BM66, TRPA_BURCA ;  B1K366, TRPA_BURCC ;  A0AZ71, TRPA_BURCH ;
DR   B4EFK2, TRPA_BURCJ ;  A9AMA5, TRPA_BURM1 ;  A3MBU6, TRPA_BURM7 ;
DR   A2S138, TRPA_BURM9 ;  Q62AJ6, TRPA_BURMA ;  A1UZ42, TRPA_BURMS ;
DR   A3P7M8, TRPA_BURP0 ;  A3NM66, TRPA_BURP6 ;  B2JQF0, TRPA_BURP8 ;
DR   B2T9N0, TRPA_BURPP ;  Q63JM0, TRPA_BURPS ;  Q393Y2, TRPA_BURS3 ;
DR   Q2T7G9, TRPA_BURTA ;  A4XLM3, TRPA_CALS8 ;  A8FKD8, TRPA_CAMJ8 ;
DR   A7H522, TRPA_CAMJD ;  Q9PIF1, TRPA_CAMJE ;  A1VY70, TRPA_CAMJJ ;
DR   Q5HWB8, TRPA_CAMJR ;  Q3ABS4, TRPA_CARHZ ;  B8H661, TRPA_CAUCN ;
DR   P12291, TRPA_CAUCR ;  B0T694, TRPA_CAUSK ;  A9WFI5, TRPA_CHLAA ;
DR   B8G5G4, TRPA_CHLAD ;  Q3AR00, TRPA_CHLCH ;  Q822W2, TRPA_CHLCV ;
DR   Q254T1, TRPA_CHLFF ;  B3EGF7, TRPA_CHLL2 ;  B3QPB1, TRPA_CHLP8 ;
DR   B3ENW0, TRPA_CHLPB ;  A1BHS2, TRPA_CHLPD ;  B9LKB2, TRPA_CHLSY ;
DR   Q8KEZ7, TRPA_CHLTE ;  O84173, TRPA_CHLTR ;  Q1QY41, TRPA_CHRSD ;
DR   Q7NUD9, TRPA_CHRVO ;  A8AG60, TRPA_CITK8 ;  Q97EF6, TRPA_CLOAB ;
DR   A6LU97, TRPA_CLOB8 ;  B9E152, TRPA_CLOK1 ;  A5N7P1, TRPA_CLOK5 ;
DR   C3PKY7, TRPA_CORA7 ;  Q6NEB5, TRPA_CORDI ;  Q8FLJ5, TRPA_COREF ;
DR   A4QI77, TRPA_CORGB ;  P06562, TRPA_CORGL ;  B1VH82, TRPA_CORU7 ;
DR   B6J7I2, TRPA_COXB1 ;  A9KE95, TRPA_COXBN ;  A9NDN6, TRPA_COXBR ;
DR   Q83CG2, TRPA_COXBU ;  Q46YW7, TRPA_CUPPJ ;  B3R113, TRPA_CUPTR ;
DR   B1WNQ1, TRPA_CYAA5 ;  O22018, TRPA_CYAME ;  B8HPH2, TRPA_CYAP4 ;
DR   B7JUK2, TRPA_CYAP8 ;  Q47HQ4, TRPA_DECAR ;  Q3Z6G1, TRPA_DEHE1 ;
DR   A5FPL3, TRPA_DEHSB ;  Q3ZZ10, TRPA_DEHSC ;  Q9RVT0, TRPA_DEIRA ;
DR   A9BNH8, TRPA_DELAS ;  B8FA37, TRPA_DESAA ;  C6C1D1, TRPA_DESAD ;
DR   C0QMA1, TRPA_DESAH ;  B8J160, TRPA_DESDA ;  C4XI54, TRPA_DESMR ;
DR   A8ZZW7, TRPA_DESOH ;  Q6AMR6, TRPA_DESPS ;  Q72EU7, TRPA_DESVH ;
DR   A1VGB6, TRPA_DESVV ;  B5YD09, TRPA_DICT6 ;  B8DZP8, TRPA_DICTD ;
DR   A7ZL78, TRPA_ECO24 ;  B7UR66, TRPA_ECO27 ;  B7ML76, TRPA_ECO45 ;
DR   B7L492, TRPA_ECO55 ;  Q8X7B5, TRPA_ECO57 ;  B5YZP0, TRPA_ECO5E ;
DR   B7NVN0, TRPA_ECO7I ;  B7MU99, TRPA_ECO81 ;  B7LY16, TRPA_ECO8A ;
DR   C4ZTV3, TRPA_ECOBW ;  B1XBK9, TRPA_ECODH ;  A7ZZJ6, TRPA_ECOHS ;
DR   A1AAN0, TRPA_ECOK1 ;  Q0TIB0, TRPA_ECOL5 ;  Q8FHW0, TRPA_ECOL6 ;
DR   B1ITJ5, TRPA_ECOLC ;  P0A877, TRPA_ECOLI ;  B7N473, TRPA_ECOLU ;
DR   B6I9X4, TRPA_ECOSE ;  B1LH32, TRPA_ECOSM ;  Q1RCA7, TRPA_ECOUT ;
DR   C5BDB6, TRPA_EDWI9 ;  A4WB03, TRPA_ENT38 ;  P00930, TRPA_ENTAE ;
DR   A7MMG7, TRPA_ENTS8 ;  Q6D4T9, TRPA_ERWCT ;  B2VKT1, TRPA_ERWT9 ;
DR   Q2N9N0, TRPA_ERYLH ;  B7LS20, TRPA_ESCF3 ;  C4Z135, TRPA_EUBE2 ;
DR   A5FA76, TRPA_FLAJ1 ;  A6GWZ0, TRPA_FLAPJ ;  Q14FN3, TRPA_FRAT1 ;
DR   A7N9D1, TRPA_FRATF ;  Q2A5V4, TRPA_FRATH ;  B2SEK8, TRPA_FRATM ;
DR   Q0BP46, TRPA_FRATO ;  Q5NE80, TRPA_FRATT ;  A4IVS5, TRPA_FRATW ;
DR   B5EAK6, TRPA_GEOBB ;  Q5KXV2, TRPA_GEOKA ;  Q39SS2, TRPA_GEOMG ;
DR   P19867, TRPA_GEOSE ;  B9M7D5, TRPA_GEOSF ;  Q74AI3, TRPA_GEOSL ;
DR   C6E1P3, TRPA_GEOSM ;  C5D3D3, TRPA_GEOSW ;  A4IQ81, TRPA_GEOTN ;
DR   A5G6M1, TRPA_GEOUR ;  Q7NHC5, TRPA_GLOVI ;  A9HE84, TRPA_GLUDA ;
DR   Q5FRN3, TRPA_GLUOX ;  Q0BQJ0, TRPA_GRABC ;  A0M4T5, TRPA_GRAFK ;
DR   Q6B8L2, TRPA_GRATL ;  Q4QKF6, TRPA_HAEI8 ;  A5UC41, TRPA_HAEIE ;
DR   A5UEU6, TRPA_HAEIG ;  P43759, TRPA_HAEIN ;  B0UU33, TRPA_HAES2 ;
DR   A1WY05, TRPA_HALHL ;  Q5V140, TRPA_HALMA ;  B0R333, TRPA_HALS3 ;
DR   Q9HSB9, TRPA_HALSA ;  P18284, TRPA_HALVD ;  Q7VGA8, TRPA_HELHP ;
DR   B6JNB7, TRPA_HELP2 ;  B5Z8S2, TRPA_HELPG ;  Q1CRX0, TRPA_HELPH ;
DR   Q9ZJV0, TRPA_HELPJ ;  B2UV41, TRPA_HELPS ;  P56141, TRPA_HELPY ;
DR   A9B6M7, TRPA_HERA2 ;  A4G4G3, TRPA_HERAR ;  Q5QX79, TRPA_IDILO ;
DR   A6T006, TRPA_JANMA ;  Q28LB1, TRPA_JANSC ;  B5XT03, TRPA_KLEP3 ;
DR   A6T7W5, TRPA_KLEP7 ;  P17166, TRPA_LACCA ;  Q01997, TRPA_LACLA ;
DR   A2RK25, TRPA_LACLM ;  Q02YB8, TRPA_LACLS ;  Q88WH9, TRPA_LACPL ;
DR   C1D702, TRPA_LARHH ;  Q5X5Q1, TRPA_LEGPA ;  A5IBF8, TRPA_LEGPC ;
DR   Q5ZVY3, TRPA_LEGPH ;  Q5WX31, TRPA_LEGPL ;  Q6AF66, TRPA_LEIXX ;
DR   B0SDM7, TRPA_LEPBA ;  Q04U62, TRPA_LEPBJ ;  Q053M5, TRPA_LEPBL ;
DR   Q5MI53, TRPA_LEPBP ;  B1XY49, TRPA_LEPCP ;  Q72U04, TRPA_LEPIC ;
DR   Q8F150, TRPA_LEPIN ;  Q92B82, TRPA_LISIN ;  C1KVS4, TRPA_LISMC ;
DR   Q71Z41, TRPA_LISMF ;  B8DHB5, TRPA_LISMH ;  Q8Y6Q7, TRPA_LISMO ;
DR   A0AJ79, TRPA_LISW6 ;  Q2W010, TRPA_MAGSA ;  P42390, TRPA_MAIZE ;
DR   Q65TE9, TRPA_MANSM ;  A1U0X2, TRPA_MARAV ;  Q8TLP4, TRPA_METAC ;
DR   A7I4T3, TRPA_METB6 ;  Q465F4, TRPA_METBF ;  B7KSK7, TRPA_METC4 ;
DR   Q604P4, TRPA_METCA ;  A9VWE9, TRPA_METEP ;  Q60180, TRPA_METJA ;
DR   Q8TYA2, TRPA_METKA ;  A4FXH7, TRPA_METM5 ;  A9AAU6, TRPA_METM6 ;
DR   A6VFT8, TRPA_METM7 ;  Q8PT96, TRPA_METMA ;  Q6LYI9, TRPA_METMP ;
DR   B8IPW1, TRPA_METNO ;  B1ZLY7, TRPA_METPB ;  A2SHS3, TRPA_METPP ;
DR   B1LSQ8, TRPA_METRJ ;  B0UKV2, TRPA_METS4 ;  O27697, TRPA_METTH ;
DR   P26920, TRPA_METTM ;  P14637, TRPA_METVO ;  A6UP14, TRPA_METVS ;
DR   B0JXU3, TRPA_MICAN ;  A0QHG8, TRPA_MYCA1 ;  B1MBV2, TRPA_MYCA9 ;
DR   P66981, TRPA_MYCBO ;  A1KJ29, TRPA_MYCBP ;  C1ANN5, TRPA_MYCBT ;
DR   O68906, TRPA_MYCIT ;  B8ZRC1, TRPA_MYCLB ;  Q9CC53, TRPA_MYCLE ;
DR   B2HQX9, TRPA_MYCMM ;  Q740P2, TRPA_MYCPA ;  A5U2W9, TRPA_MYCTA ;
DR   P66980, TRPA_MYCTU ;  A0PP30, TRPA_MYCUA ;  Q3IQC4, TRPA_NATPD ;
DR   Q5F9Y6, TRPA_NEIG1 ;  Q9JVE0, TRPA_NEIMA ;  Q9K0D4, TRPA_NEIMB ;
DR   Q82WI1, TRPA_NITEU ;  Q1QS34, TRPA_NITHX ;  Q2Y7R5, TRPA_NITMU ;
DR   Q3JCB7, TRPA_NITOC ;  Q3SWL9, TRPA_NITWN ;  Q5YYN3, TRPA_NOCFA ;
DR   Q2G8S8, TRPA_NOVAD ;  Q8ESU5, TRPA_OCEIH ;  A6WX30, TRPA_OCHA4 ;
DR   B6JCP3, TRPA_OLICO ;  B1ZT49, TRPA_OPITP ;  A6L9J8, TRPA_PARD8 ;
DR   A1AYV3, TRPA_PARDP ;  P57854, TRPA_PASMU ;  C6DGZ4, TRPA_PECCP ;
DR   Q3A2C7, TRPA_PELCD ;  Q3B5F2, TRPA_PELLD ;  B4SEN7, TRPA_PELPB ;
DR   A1AN65, TRPA_PELPD ;  Q4FND0, TRPA_PELUB ;  A9BHQ2, TRPA_PETMO ;
DR   B4RCL1, TRPA_PHEZH ;  Q7N485, TRPA_PHOLL ;  Q6LPA3, TRPA_PHOPR ;
DR   A1VRR8, TRPA_POLNA ;  B1XV46, TRPA_POLNS ;  Q126M0, TRPA_POLSJ ;
DR   A4SWX7, TRPA_POLSQ ;  P51382, TRPA_PORPU ;  Q1XDA5, TRPA_PORYE ;
DR   B4S6H5, TRPA_PROA2 ;  A2C129, TRPA_PROM1 ;  Q7VD15, TRPA_PROMA ;
DR   B4EWH8, TRPA_PROMH ;  Q7TV26, TRPA_PROMM ;  Q7TUC8, TRPA_PROMP ;
DR   Q46LX8, TRPA_PROMT ;  A4SDQ2, TRPA_PROVI ;  Q48QG7, TRPA_PSE14 ;
DR   A6UX98, TRPA_PSEA7 ;  B7V0S0, TRPA_PSEA8 ;  Q02V45, TRPA_PSEAB ;
DR   P07344, TRPA_PSEAE ;  Q1IH21, TRPA_PSEE4 ;  Q4KKP5, TRPA_PSEF5 ;
DR   C3K568, TRPA_PSEFS ;  A4XNC8, TRPA_PSEMY ;  A5VWL2, TRPA_PSEP1 ;
DR   Q3KK58, TRPA_PSEPF ;  B0KFW2, TRPA_PSEPG ;  Q88RP7, TRPA_PSEPK ;
DR   P11081, TRPA_PSEPU ;  B1J4B0, TRPA_PSEPW ;  Q88B60, TRPA_PSESM ;
DR   P34816, TRPA_PSESY ;  Q500R5, TRPA_PSEU2 ;  A4VNJ1, TRPA_PSEU5 ;
DR   Q4FUL2, TRPA_PSYA2 ;  Q1QDK2, TRPA_PSYCK ;  A5WDG7, TRPA_PSYWF ;
DR   Q9V1G9, TRPA_PYRAB ;  Q8U094, TRPA_PYRFU ;  Q9YGA9, TRPA_PYRKO ;
DR   Q1LKI4, TRPA_RALME ;  B2U6Y7, TRPA_RALPJ ;  Q8XXY2, TRPA_RALSO ;
DR   B3PVV3, TRPA_RHIE6 ;  Q2KE81, TRPA_RHIEC ;  Q1MND5, TRPA_RHIL3 ;
DR   Q98CN6, TRPA_RHILO ;  B5ZV71, TRPA_RHILW ;  Q92TC8, TRPA_RHIME ;
DR   C3MBA0, TRPA_RHISN ;  Q7URN0, TRPA_RHOBA ;  Q21XI7, TRPA_RHOFD ;
DR   Q2J2G5, TRPA_RHOP2 ;  Q07UH0, TRPA_RHOP5 ;  Q6NDN5, TRPA_RHOPA ;
DR   Q13EQ1, TRPA_RHOPS ;  B3Q606, TRPA_RHOPT ;  A3PMM5, TRPA_RHOS1 ;
DR   Q9X4E8, TRPA_RHOS4 ;  A4WPE1, TRPA_RHOS5 ;  B9KMG7, TRPA_RHOSK ;
DR   A7NKL7, TRPA_ROSCS ;  Q161I8, TRPA_ROSDO ;  A5UXG2, TRPA_ROSS1 ;
DR   A1AXS3, TRPA_RUTMC ;  B5F4M3, TRPA_SALA4 ;  A8LX37, TRPA_SALAI ;
DR   A9MPY6, TRPA_SALAR ;  Q57NT2, TRPA_SALCH ;  B5FU65, TRPA_SALDC ;
DR   B5R3P3, TRPA_SALEP ;  B5R6M4, TRPA_SALG2 ;  B4TJK9, TRPA_SALHS ;
DR   B4T6X2, TRPA_SALNS ;  Q5PNM0, TRPA_SALPA ;  A9MWR3, TRPA_SALPB ;
DR   C0Q3N3, TRPA_SALPC ;  B5BIC0, TRPA_SALPK ;  Q2S1Z2, TRPA_SALRD ;
DR   B4TX39, TRPA_SALSV ;  Q8Z7E0, TRPA_SALTI ;  A4X9N0, TRPA_SALTO ;
DR   P00929, TRPA_SALTY ;  A8GF83, TRPA_SERP5 ;  A1S7I3, TRPA_SHEAM ;
DR   A3D631, TRPA_SHEB5 ;  A6WPX2, TRPA_SHEB8 ;  A9KTR8, TRPA_SHEB9 ;
DR   Q8ECU9, TRPA_SHEON ;  B2U0F1, TRPA_SHIB3 ;  Q31ZV3, TRPA_SHIBS ;
DR   Q32GT0, TRPA_SHIDS ;  Q0T5D6, TRPA_SHIF8 ;  P0A878, TRPA_SHIFL ;
DR   Q3Z108, TRPA_SHISS ;  Q5LV87, TRPA_SILPO ;  A6UEI2, TRPA_SINMW ;
DR   Q2NT53, TRPA_SODGM ;  Q01NI9, TRPA_SOLUE ;  A5V9W7, TRPA_SPHWW ;
DR   A7X240, TRPA_STAA1 ;  A6U1J5, TRPA_STAA2 ;  Q2FH63, TRPA_STAA3 ;
DR   Q2FYR3, TRPA_STAA8 ;  A5ISQ5, TRPA_STAA9 ;  Q2YXZ6, TRPA_STAAB ;
DR   Q5HG46, TRPA_STAAC ;  A6QGS5, TRPA_STAAE ;  P66982, TRPA_STAAM ;
DR   P66983, TRPA_STAAN ;  Q6GH32, TRPA_STAAR ;  Q6G9I6, TRPA_STAAS ;
DR   A8Z245, TRPA_STAAT ;  Q8NWU1, TRPA_STAAW ;  B9DP27, TRPA_STACT ;
DR   Q5HPG9, TRPA_STAEQ ;  Q8CPB0, TRPA_STAES ;  Q4L680, TRPA_STAHJ ;
DR   Q49XH9, TRPA_STAS1 ;  Q82A81, TRPA_STRAW ;  O68816, TRPA_STRCO ;
DR   A8AW06, TRPA_STRGC ;  Q8DVF2, TRPA_STRMU ;  Q04IZ0, TRPA_STRP2 ;
DR   B5E7M2, TRPA_STRP4 ;  C1C965, TRPA_STRP7 ;  B1I7S6, TRPA_STRPI ;
DR   B8ZN58, TRPA_STRPJ ;  Q97P33, TRPA_STRPN ;  Q8DNM9, TRPA_STRR6 ;
DR   A3CLM2, TRPA_STRSV ;  Q5LYI8, TRPA_STRT1 ;  Q5M351, TRPA_STRT2 ;
DR   Q03JC2, TRPA_STRTD ;  C1CG41, TRPA_STRZJ ;  C1CMD2, TRPA_STRZP ;
DR   C1CT50, TRPA_STRZT ;  Q4J8X8, TRPA_SULAC ;  A8Z5Y2, TRPA_SULMW ;
DR   P50382, TRPA_SULSO ;  Q971Z6, TRPA_SULTO ;  Q67PJ3, TRPA_SYMTH ;
DR   Q2LUE0, TRPA_SYNAS ;  Q31R76, TRPA_SYNE7 ;  A0LJ55, TRPA_SYNFM ;
DR   Q8KX32, TRPA_SYNP2 ;  Q5N324, TRPA_SYNP6 ;  Q7TTU8, TRPA_SYNPX ;
DR   Q3AYG5, TRPA_SYNS9 ;  Q0B002, TRPA_SYNWW ;  P77960, TRPA_SYNY3 ;
DR   Q8DLN9, TRPA_THEEB ;  Q47QR3, TRPA_THEFY ;  P50908, TRPA_THEMA ;
DR   B9K6Z6, TRPA_THENN ;  A5IKT4, TRPA_THEP1 ;  B0K8T7, TRPA_THEP3 ;
DR   B0K2T8, TRPA_THEPX ;  B1LA15, TRPA_THESQ ;  P16608, TRPA_THET2 ;
DR   Q5SJC0, TRPA_THET8 ;  Q8R9N0, TRPA_THETN ;  Q31HH3, TRPA_THICR ;
DR   Q3SHM0, TRPA_THIDA ;  B8GQE5, TRPA_THISH ;  C4LC88, TRPA_TOLAT ;
DR   Q10W95, TRPA_TRIEI ;  A1WSF0, TRPA_VEREI ;  A5CVK4, TRPA_VESOH ;
DR   A5F207, TRPA_VIBC3 ;  Q9KST7, TRPA_VIBCH ;  C3LLL5, TRPA_VIBCM ;
DR   Q5E624, TRPA_VIBF1 ;  B5FDB6, TRPA_VIBFM ;  Q9RCE7, TRPA_VIBME ;
DR   P22095, TRPA_VIBPA ;  B7VGU8, TRPA_VIBSL ;  Q8D8B1, TRPA_VIBVU ;
DR   Q7MM57, TRPA_VIBVY ;  Q7M877, TRPA_WOLSU ;  Q8PJ29, TRPA_XANAC ;
DR   Q3BRL7, TRPA_XANC5 ;  Q4UWD0, TRPA_XANC8 ;  B0RR86, TRPA_XANCB ;
DR   Q8P7S0, TRPA_XANCP ;  Q2P0U3, TRPA_XANOM ;  B2SVN5, TRPA_XANOP ;
DR   Q5GXR6, TRPA_XANOR ;  B2I9J3, TRPA_XYLF2 ;  Q9PDK3, TRPA_XYLFA ;
DR   B0U6K7, TRPA_XYLFM ;  Q87DR8, TRPA_XYLFT ;  A1JPY2, TRPA_YERE8 ;
DR   A7FI34, TRPA_YERP3 ;  Q1C7P3, TRPA_YERPA ;  B2K3W1, TRPA_YERPB ;
DR   Q8ZEH0, TRPA_YERPE ;  A9R995, TRPA_YERPG ;  Q1CJ29, TRPA_YERPN ;
DR   A4TJ68, TRPA_YERPP ;  Q66AK5, TRPA_YERPS ;  B1JKS3, TRPA_YERPY ;
DR   Q5NPZ7, TRPA_ZYMMO ;  Q9Y8T5, TRPB1_AERPE;  O66923, TRPB1_AQUAE;
DR   P14671, TRPB1_ARATH;  O28672, TRPB1_ARCFU;  Q822W9, TRPB1_CHLCV;
DR   Q8FLJ6, TRPB1_COREF;  P43283, TRPB1_MAIZE;  Q8TLP3, TRPB1_METAC;
DR   Q8PT95, TRPB1_METMA;  O27696, TRPB1_METTH;  Q8YZP7, TRPB1_NOSS1;
DR   Q9V1G8, TRPB1_PYRAB;  Q8U093, TRPB1_PYRFU;  Q9YGB0, TRPB1_PYRKO;
DR   P50383, TRPB1_SULSO;  Q971Z5, TRPB1_SULTO;  P50909, TRPB1_THEMA;
DR   P22097, TRPB1_VIBPA;  Q7M9S1, TRPB1_WOLSU;  Q9Y9H2, TRPB2_AERPE;
DR   O67409, TRPB2_AQUAE;  O29028, TRPB2_ARCFU;  Q822W3, TRPB2_CHLCV;
DR   Q8FT12, TRPB2_COREF;  P43284, TRPB2_MAIZE;  Q8TL44, TRPB2_METAC;
DR   Q8Q001, TRPB2_METMA;  O27520, TRPB2_METTH;  P26921, TRPB2_METTM;
DR   Q8YQM6, TRPB2_NOSS1;  Q9V150, TRPB2_PYRAB;  Q8U0J5, TRPB2_PYRFU;
DR   Q5JDJ1, TRPB2_PYRKO;  Q97TX6, TRPB2_SULSO;  Q970N1, TRPB2_SULTO;
DR   Q9WZ09, TRPB2_THEMA;  Q87IM1, TRPB2_VIBPA;  Q7M8W7, TRPB2_WOLSU;
DR   A1TLG8, TRPB_ACIAC ;  Q6FEF1, TRPB_ACIAD ;  Q1ISI9, TRPB_ACIBL ;
DR   P16706, TRPB_ACICA ;  A5FY57, TRPB_ACICJ ;  B7J4S9, TRPB_ACIF2 ;
DR   B5EK18, TRPB_ACIF5 ;  A3MZI7, TRPB_ACTP2 ;  B3GX46, TRPB_ACTP7 ;
DR   B0BU72, TRPB_ACTPJ ;  A6VPD9, TRPB_ACTSZ ;  A0KMD0, TRPB_AERHH ;
DR   A4SKT1, TRPB_AERS4 ;  B9JG43, TRPB_AGRRK ;  Q8UJB0, TRPB_AGRT5 ;
DR   B9JXV6, TRPB_AGRVS ;  B6EJA3, TRPB_ALISL ;  A6TM76, TRPB_ALKMQ ;
DR   B4S1J4, TRPB_ALTMD ;  Q3MBV3, TRPB_ANAVT ;  B7GHQ9, TRPB_ANOFW ;
DR   B6YQ32, TRPB_AZOPC ;  C1DH66, TRPB_AZOVD ;  A7Z616, TRPB_BACA2 ;
DR   C3P3U0, TRPB_BACAA ;  C3LAV8, TRPB_BACAC ;  A0RB64, TRPB_BACAH ;
DR   Q81TL8, TRPB_BACAN ;  Q73BQ7, TRPB_BACC1 ;  B7IM76, TRPB_BACC2 ;
DR   C1ELF0, TRPB_BACC3 ;  B7HH01, TRPB_BACC4 ;  B7I0F2, TRPB_BACC7 ;
DR   B9IU38, TRPB_BACCQ ;  Q81GG5, TRPB_BACCR ;  Q63EC7, TRPB_BACCZ ;
DR   Q5LBZ8, TRPB_BACFN ;  Q64SX9, TRPB_BACFR ;  Q9KCB0, TRPB_BACHD ;
DR   Q6HLU4, TRPB_BACHK ;  Q65I35, TRPB_BACLD ;  A8FEJ8, TRPB_BACP2 ;
DR   Q5WGS1, TRPB_BACSK ;  P07600, TRPB_BACSU ;  Q8AAD2, TRPB_BACTN ;
DR   A6L7M5, TRPB_BACV8 ;  A9VJW2, TRPB_BACWK ;  B2IF48, TRPB_BEII9 ;
DR   Q7VR00, TRPB_BLOFL ;  Q492N6, TRPB_BLOPB ;  Q7WD04, TRPB_BORBR ;
DR   Q7W5G8, TRPB_BORPA ;  A9IIE0, TRPB_BORPD ;  Q7VTF1, TRPB_BORPE ;
DR   Q89WE5, TRPB_BRAJA ;  A5E8A4, TRPB_BRASB ;  A4YJI6, TRPB_BRASO ;
DR   B2S9A5, TRPB_BRUA1 ;  Q2YQW5, TRPB_BRUA2 ;  Q57AF0, TRPB_BRUAB ;
DR   A9M9U2, TRPB_BRUC2 ;  C0RFZ4, TRPB_BRUMB ;  Q8YE60, TRPB_BRUME ;
DR   B0CJK8, TRPB_BRUSI ;  Q8FXY4, TRPB_BRUSU ;  Q44685, TRPB_BUCAI ;
DR   P42391, TRPB_BUCAP ;  P59458, TRPB_BUCBP ;  O68428, TRPB_BUCDN ;
DR   Q44687, TRPB_BUCMH ;  Q44686, TRPB_BUCRM ;  Q44688, TRPB_BUCRP ;
DR   Q59169, TRPB_BUCSC ;  O50046, TRPB_CAMAC ;  A8FKD7, TRPB_CAMJ8 ;
DR   A7H523, TRPB_CAMJD ;  Q9PIF2, TRPB_CAMJE ;  A1VY69, TRPB_CAMJJ ;
DR   Q5HWB9, TRPB_CAMJR ;  P12290, TRPB_CAUCR ;  Q8KF11, TRPB_CHLTE ;
DR   O84172, TRPB_CHLTR ;  Q7NUD8, TRPB_CHRVO ;  A8AG61, TRPB_CITK8 ;
DR   A5CRV6, TRPB_CLAM3 ;  B0REU1, TRPB_CLAMS ;  Q97EF5, TRPB_CLOAB ;
DR   A6LU96, TRPB_CLOB8 ;  B2V2T4, TRPB_CLOBA ;  B2TM49, TRPB_CLOBB ;
DR   B9E151, TRPB_CLOK1 ;  A5N7P0, TRPB_CLOK5 ;  A0PYH3, TRPB_CLONN ;
DR   A4QI76, TRPB_CORGB ;  P06561, TRPB_CORGL ;  Q47HQ5, TRPB_DECAR ;
DR   Q9RVT1, TRPB_DEIRA ;  B8D4P0, TRPB_DESK1 ;  A8LSF9, TRPB_DINSH ;
DR   A7ZL79, TRPB_ECO24 ;  B7UR67, TRPB_ECO27 ;  B7ML77, TRPB_ECO45 ;
DR   B7L493, TRPB_ECO55 ;  Q8X7B6, TRPB_ECO57 ;  B5YZP1, TRPB_ECO5E ;
DR   B7NVN1, TRPB_ECO7I ;  B7MUA0, TRPB_ECO81 ;  B7LY17, TRPB_ECO8A ;
DR   B1XBL0, TRPB_ECODH ;  A7ZZJ7, TRPB_ECOHS ;  A1AAN1, TRPB_ECOK1 ;
DR   Q0TIA9, TRPB_ECOL5 ;  Q8FHV9, TRPB_ECOL6 ;  B1ITJ4, TRPB_ECOLC ;
DR   P0A879, TRPB_ECOLI ;  B7N474, TRPB_ECOLU ;  B6I9X5, TRPB_ECOSE ;
DR   B1LH31, TRPB_ECOSM ;  Q1RCA6, TRPB_ECOUT ;  C5BDB7, TRPB_EDWI9 ;
DR   B2KCI5, TRPB_ELUMP ;  A4WB02, TRPB_ENT38 ;  P14552, TRPB_ENTAE ;
DR   A7MMG1, TRPB_ENTS8 ;  Q6D4U0, TRPB_ERWCT ;  B2VKT2, TRPB_ERWT9 ;
DR   B7LS19, TRPB_ESCF3 ;  B1YLS4, TRPB_EXIS2 ;  A7HMG8, TRPB_FERNB ;
DR   B0TWI3, TRPB_FRAP2 ;  Q14FN2, TRPB_FRAT1 ;  A7N9D2, TRPB_FRATF ;
DR   Q2A5V3, TRPB_FRATH ;  B2SEK7, TRPB_FRATM ;  A0Q8M6, TRPB_FRATN ;
DR   Q0BP45, TRPB_FRATO ;  Q5NE79, TRPB_FRATT ;  A4IVS4, TRPB_FRATW ;
DR   Q8RGH8, TRPB_FUSNN ;  P19868, TRPB_GEOSE ;  A4IQ82, TRPB_GEOTN ;
DR   Q7NGX9, TRPB_GLOVI ;  Q4QKF5, TRPB_HAEI8 ;  A5UC40, TRPB_HAEIE ;
DR   A5UEU5, TRPB_HAEIG ;  P43760, TRPB_HAEIN ;  B0UU34, TRPB_HAES2 ;
DR   B0R332, TRPB_HALS3 ;  Q9HSC0, TRPB_HALSA ;  P18285, TRPB_HALVD ;
DR   Q7VGA7, TRPB_HELHP ;  Q9ZJU9, TRPB_HELPJ ;  P56142, TRPB_HELPY ;
DR   Q28LA6, TRPB_JANSC ;  B5XT02, TRPB_KLEP3 ;  A6T7W6, TRPB_KLEP7 ;
DR   Q03CY3, TRPB_LACC3 ;  P17167, TRPB_LACCA ;  B3W6W6, TRPB_LACCB ;
DR   Q01998, TRPB_LACLA ;  A2RK24, TRPB_LACLM ;  Q02YB7, TRPB_LACLS ;
DR   Q88WI0, TRPB_LACPL ;  Q5X5Q2, TRPB_LEGPA ;  A5IBF7, TRPB_LEGPC ;
DR   Q5ZVY4, TRPB_LEGPH ;  Q5WX32, TRPB_LEGPL ;  Q6AF67, TRPB_LEIXX ;
DR   B0SDM8, TRPB_LEPBA ;  Q04U63, TRPB_LEPBJ ;  Q053M6, TRPB_LEPBL ;
DR   B0SM57, TRPB_LEPBP ;  B1XY48, TRPB_LEPCP ;  Q72U05, TRPB_LEPIC ;
DR   Q8F149, TRPB_LEPIN ;  Q92B81, TRPB_LISIN ;  C1KVS5, TRPB_LISMC ;
DR   Q71Z40, TRPB_LISMF ;  B8DHB4, TRPB_LISMH ;  Q8Y6Q6, TRPB_LISMO ;
DR   A0AJ80, TRPB_LISW6 ;  Q65TF0, TRPB_MANSM ;  Q11KK9, TRPB_MESSB ;
DR   A6UW25, TRPB_META3 ;  B7L1H4, TRPB_METC4 ;  Q604P3, TRPB_METCA ;
DR   Q1H0M1, TRPB_METFK ;  Q60179, TRPB_METJA ;  Q8TX91, TRPB_METKA ;
DR   A2STA4, TRPB_METLZ ;  B8I9V8, TRPB_METNO ;  B1ZG57, TRPB_METPB ;
DR   A2SHS4, TRPB_METPP ;  B1LSI6, TRPB_METRJ ;  B0UIA8, TRPB_METS4 ;
DR   P14638, TRPB_METVO ;  P66985, TRPB_MYCBO ;  O68905, TRPB_MYCIT ;
DR   Q9CC54, TRPB_MYCLE ;  P66984, TRPB_MYCTU ;  Q5F9W3, TRPB_NEIG1 ;
DR   B4RJV8, TRPB_NEIG2 ;  Q84GJ9, TRPB_NEIGO ;  A9M354, TRPB_NEIM0 ;
DR   Q9JVC0, TRPB_NEIMA ;  Q9K0B5, TRPB_NEIMB ;  A1KSW2, TRPB_NEIMF ;
DR   Q0AGX5, TRPB_NITEC ;  Q82WI2, TRPB_NITEU ;  Q2Y7R4, TRPB_NITMU ;
DR   Q2G8S7, TRPB_NOVAD ;  Q8ESU4, TRPB_OCEIH ;  A6WX28, TRPB_OCHA4 ;
DR   B6JCP2, TRPB_OLICO ;  A6L9K4, TRPB_PARD8 ;  A1B8L3, TRPB_PARDP ;
DR   A7HPD3, TRPB_PARL1 ;  P54203, TRPB_PASMU ;  C6DGZ5, TRPB_PECCP ;
DR   B4RCL0, TRPB_PHEZH ;  Q7N486, TRPB_PHOLL ;  Q6LPA4, TRPB_PHOPR ;
DR   Q6L271, TRPB_PICTO ;  A1VRR7, TRPB_POLNA ;  Q126M1, TRPB_POLSJ ;
DR   A3PAN2, TRPB_PROM0 ;  A2BZZ2, TRPB_PROM1 ;  A8G2H0, TRPB_PROM2 ;
DR   A9BD24, TRPB_PROM4 ;  A2BUE1, TRPB_PROM5 ;  Q31D17, TRPB_PROM9 ;
DR   Q7VE26, TRPB_PROMA ;  B4EWH7, TRPB_PROMH ;  Q7TUL2, TRPB_PROMM ;
DR   Q7TUH0, TRPB_PROMP ;  A2BNV9, TRPB_PROMS ;  Q46HK9, TRPB_PROMT ;
DR   Q48QG6, TRPB_PSE14 ;  Q15RZ5, TRPB_PSEA6 ;  P07345, TRPB_PSEAE ;
DR   Q1IH20, TRPB_PSEE4 ;  Q4KKP4, TRPB_PSEF5 ;  A5VWL3, TRPB_PSEP1 ;
DR   Q3KK59, TRPB_PSEPF ;  B0KFW3, TRPB_PSEPG ;  Q88RP6, TRPB_PSEPK ;
DR   P11080, TRPB_PSEPU ;  B1J4B1, TRPB_PSEPW ;  Q849P2, TRPB_PSESH ;
DR   Q88B61, TRPB_PSESM ;  P34817, TRPB_PSESY ;  Q500R4, TRPB_PSEU2 ;
DR   A1STT0, TRPB_PSYIN ;  Q8ZV44, TRPB_PYRAE ;  A4WKQ9, TRPB_PYRAR ;
DR   O59265, TRPB_PYRHO ;  A1RVT1, TRPB_PYRIL ;  Q8XXY0, TRPB_RALSO ;
DR   B3PVV2, TRPB_RHIE6 ;  Q2KE82, TRPB_RHIEC ;  Q1MND6, TRPB_RHIL3 ;
DR   Q98CN7, TRPB_RHILO ;  B5ZV70, TRPB_RHILW ;  Q92TC9, TRPB_RHIME ;
DR   C3MB99, TRPB_RHISN ;  Q7UKG9, TRPB_RHOBA ;  Q21XI6, TRPB_RHOFD ;
DR   Q2J2G4, TRPB_RHOP2 ;  Q07UH1, TRPB_RHOP5 ;  Q6NDN6, TRPB_RHOPA ;
DR   Q21CB9, TRPB_RHOPB ;  Q13EQ2, TRPB_RHOPS ;  B3Q605, TRPB_RHOPT ;
DR   Q9X4E5, TRPB_RHOS4 ;  Q161H9, TRPB_ROSDO ;  A1AXS9, TRPB_RUTMC ;
DR   B5F4M4, TRPB_SALA4 ;  A9MPY7, TRPB_SALAR ;  Q57NT3, TRPB_SALCH ;
DR   B5FU66, TRPB_SALDC ;  B5R3P4, TRPB_SALEP ;  B5R6M5, TRPB_SALG2 ;
DR   B4TJK8, TRPB_SALHS ;  B4T6X1, TRPB_SALNS ;  Q5PD17, TRPB_SALPA ;
DR   A9MWR4, TRPB_SALPB ;  C0Q3N4, TRPB_SALPC ;  B5BIC1, TRPB_SALPK ;
DR   B4TX38, TRPB_SALSV ;  P0A2K2, TRPB_SALTI ;  P0A2K1, TRPB_SALTY ;
DR   A8GF82, TRPB_SERP5 ;  A1S7I2, TRPB_SHEAM ;  A3D630, TRPB_SHEB5 ;
DR   A6WPX1, TRPB_SHEB8 ;  A9KTR7, TRPB_SHEB9 ;  Q12LE2, TRPB_SHEDO ;
DR   Q084N8, TRPB_SHEFN ;  B0TP63, TRPB_SHEHH ;  A3QF73, TRPB_SHELP ;
DR   Q8ECV0, TRPB_SHEON ;  A8H2X4, TRPB_SHEPA ;  A4Y845, TRPB_SHEPC ;
DR   B8CLM6, TRPB_SHEPW ;  A0KVD1, TRPB_SHESA ;  Q0HK81, TRPB_SHESM ;
DR   Q0HWI3, TRPB_SHESR ;  A1RIE3, TRPB_SHESW ;  B1KK02, TRPB_SHEWM ;
DR   B2U0F2, TRPB_SHIB3 ;  Q31ZV4, TRPB_SHIBS ;  Q32GS9, TRPB_SHIDS ;
DR   Q0T5D5, TRPB_SHIF8 ;  P0A880, TRPB_SHIFL ;  Q3Z109, TRPB_SHISS ;
DR   Q5LV94, TRPB_SILPO ;  Q1GK77, TRPB_SILST ;  A6UEI1, TRPB_SINMW ;
DR   Q2NT52, TRPB_SODGM ;  A7X238, TRPB_STAA1 ;  A6U1J4, TRPB_STAA2 ;
DR   Q2FH64, TRPB_STAA3 ;  Q2FYR4, TRPB_STAA8 ;  A5ISQ4, TRPB_STAA9 ;
DR   Q2YXX2, TRPB_STAAB ;  Q5HG47, TRPB_STAAC ;  A6QGS4, TRPB_STAAE ;
DR   P66986, TRPB_STAAM ;  P66987, TRPB_STAAN ;  Q6GH33, TRPB_STAAR ;
DR   Q6G9I7, TRPB_STAAS ;  A8Z244, TRPB_STAAT ;  Q8NWU2, TRPB_STAAW ;
DR   Q5HPH0, TRPB_STAEQ ;  Q8CPB1, TRPB_STAES ;  Q49XH8, TRPB_STAS1 ;
DR   Q82A82, TRPB_STRAW ;  O05625, TRPB_STRCO ;  B1W0P0, TRPB_STRGG ;
DR   B4SQU8, TRPB_STRM5 ;  B2FNZ1, TRPB_STRMK ;  Q8DVF3, TRPB_STRMU ;
DR   Q04IY9, TRPB_STRP2 ;  B5E7M3, TRPB_STRP4 ;  C1C966, TRPB_STRP7 ;
DR   B1I7S7, TRPB_STRPI ;  B8ZN59, TRPB_STRPJ ;  Q97P32, TRPB_STRPN ;
DR   B2ISS1, TRPB_STRPS ;  Q8DNM8, TRPB_STRR6 ;  Q5LYI7, TRPB_STRT1 ;
DR   Q5M350, TRPB_STRT2 ;  Q03JC1, TRPB_STRTD ;  C1CG42, TRPB_STRZJ ;
DR   C1CMD3, TRPB_STRZP ;  C1CT51, TRPB_STRZT ;  B2V8W5, TRPB_SULSY ;
DR   Q2JLD7, TRPB_SYNJB ;  A5GP60, TRPB_SYNPW ;  Q7TTS6, TRPB_SYNPX ;
DR   Q0I6V1, TRPB_SYNS3 ;  Q3AW11, TRPB_SYNS9 ;  Q3AGY2, TRPB_SYNSC ;
DR   Q59992, TRPB_SYNY3 ;  B7IHA8, TRPB_THEAB ;  Q9HKD2, TRPB_THEAC ;
DR   Q8DG49, TRPB_THEEB ;  C5A1P4, TRPB_THEGJ ;  A8F8F7, TRPB_THELT ;
DR   B6YSU5, TRPB_THEON ;  B0K8T6, TRPB_THEP3 ;  B0K2T9, TRPB_THEPX ;
DR   P16609, TRPB_THET2 ;  Q5SJB9, TRPB_THET8 ;  Q8R9M9, TRPB_THETN ;
DR   Q97A51, TRPB_THEVO ;  Q3SHL9, TRPB_THIDA ;  C4LC89, TRPB_TOLAT ;
DR   Q118P8, TRPB_TRIEI ;  A1WSF1, TRPB_VEREI ;  A5CVH4, TRPB_VESOH ;
DR   A5F208, TRPB_VIBC3 ;  Q9KST6, TRPB_VIBCH ;  C3LLL6, TRPB_VIBCM ;
DR   Q5E623, TRPB_VIBF1 ;  B5FDB7, TRPB_VIBFM ;  A7MRY0, TRPB_VIBHB ;
DR   Q9RCE8, TRPB_VIBME ;  B7VGU7, TRPB_VIBSL ;  Q8D8B2, TRPB_VIBVU ;
DR   Q7MM56, TRPB_VIBVY ;  Q8PJ28, TRPB_XANAC ;  Q3BRL3, TRPB_XANC5 ;
DR   Q4UWD2, TRPB_XANC8 ;  B0RR84, TRPB_XANCB ;  Q8P7R8, TRPB_XANCP ;
DR   Q2P0U2, TRPB_XANOM ;  B2SVN7, TRPB_XANOP ;  B2I9J2, TRPB_XYLF2 ;
DR   Q9PDK4, TRPB_XYLFA ;  B0U6K6, TRPB_XYLFM ;  Q87DR9, TRPB_XYLFT ;
DR   A1JPX6, TRPB_YERE8 ;  A7FI33, TRPB_YERP3 ;  Q1C7P2, TRPB_YERPA ;
DR   B2K3W2, TRPB_YERPB ;  Q8ZEG9, TRPB_YERPE ;  Q1CJ28, TRPB_YERPN ;
DR   A4TJ67, TRPB_YERPP ;  Q66AK4, TRPB_YERPS ;  B1JKS2, TRPB_YERPY ;
DR   A8NEP3, TRP_COPC7  ;  P16578, TRP_COPCI  ;  P13228, TRP_NEUCR  ;
DR   O13831, TRP_SCHPO  ;  P00931, TRP_YEAST  ;
//
ID   4.2.1.21
DE   Transferred entry: 4.2.1.22.
//
ID   4.2.1.22
DE   Cystathionine beta-synthase.
AN   Beta-thionase.
AN   Methylcysteine synthase.
AN   Serine sulfhydrase.
CA   L-serine + L-homocysteine = L-cystathionine + H(2)O.
CF   Pyridoxal 5'-phosphate.
CC   -!- A multifunctional enzyme: catalyzes beta-replacement reaction between
CC       L-serine, L-cysteine, cysteine thioethers or some other beta-
CC       substituted alpha-L-amino acids and a variety of mercaptans.
CC   -!- Formerly EC 4.2.1.21.
PR   PROSITE; PDOC00700;
DR   P46794, CBS_DICDI  ;  P35520, CBS_HUMAN  ;  Q58H57, CBS_MACFA  ;
DR   Q91WT9, CBS_MOUSE  ;  Q9N0V7, CBS_RABIT  ;  P32232, CBS_RAT    ;
DR   P32582, CBS_YEAST  ;  Q9YBL2, CYSO_AERPE ;  Q7D8W0, Y1077_MYCTU;
//
ID   4.2.1.23
DE   Deleted entry.
//
ID   4.2.1.24
DE   Porphobilinogen synthase.
AN   Aminolevulinate dehydratase.
AN   Delta-aminolevulinic acid dehydratase.
CA   2 5-aminolevulinate = porphobilinogen + 2 H(2)O.
CF   Zinc.
PR   PROSITE; PDOC00153;
DR   O67876, HEM2_AQUAE ;  Q9SFH9, HEM2_ARATH ;  O28305, HEM2_ARCFU ;
DR   Q750E0, HEM2_ASHGO ;  Q9K8G2, HEM2_BACHD ;  P30950, HEM2_BACSU ;
DR   Q58DK5, HEM2_BOVIN ;  P45622, HEM2_BRAJA ;  O42768, HEM2_CANGA ;
DR   Q9PLU4, HEM2_CHLMU ;  Q59334, HEM2_CHLP8 ;  Q9Z7G1, HEM2_CHLPN ;
DR   Q42682, HEM2_CHLRE ;  Q8KCJ0, HEM2_CHLTE ;  O84638, HEM2_CHLTR ;
DR   Q59295, HEM2_CLOJO ;  Q55E06, HEM2_DICDI ;  P0ACB2, HEM2_ECOLI ;
DR   Q9ZMR8, HEM2_HELPJ ;  P56074, HEM2_HELPY ;  Q42836, HEM2_HORVU ;
DR   P13716, HEM2_HUMAN ;  Q60HH9, HEM2_MACFA ;  Q60178, HEM2_METJA ;
DR   Q02250, HEM2_METSC ;  O26839, HEM2_METTH ;  P10518, HEM2_MOUSE ;
DR   P46723, HEM2_MYCLE ;  O33357, HEM2_MYCTU ;  Q5Z8V9, HEM2_ORYSJ ;
DR   P30124, HEM2_PEA   ;  Q43058, HEM2_PHYPA ;  Q5R971, HEM2_PONAB ;
DR   P77923, HEM2_PROFF ;  Q59643, HEM2_PSEAE ;  P06214, HEM2_RAT   ;
DR   P42504, HEM2_RHOCA ;  P78974, HEM2_SCHPO ;  P45623, HEM2_SELMA ;
DR   P0ACB3, HEM2_SHIFL ;  P43210, HEM2_SOYBN ;  P24493, HEM2_SPIOL ;
DR   Q2FXR3, HEM2_STAA8 ;  Q5HFA4, HEM2_STAAC ;  P64333, HEM2_STAAM ;
DR   P64334, HEM2_STAAN ;  Q6GG37, HEM2_STAAR ;  Q6G8Q7, HEM2_STAAS ;
DR   P0C1R9, HEM2_STAAU ;  P64335, HEM2_STAAW ;  Q5HNN5, HEM2_STAEQ ;
DR   Q8CNZ0, HEM2_STAES ;  P54919, HEM2_STRCO ;  P43087, HEM2_SYNE7 ;
DR   P77969, HEM2_SYNY3 ;  P05373, HEM2_YEAST ;
//
ID   4.2.1.25
DE   L-arabinonate dehydratase.
AN   L-arabinonate hydro-lyase.
CA   L-arabinonate = 2-dehydro-3-deoxy-L-arabinonate + H(2)O.
//
ID   4.2.1.26
DE   Transferred entry: 4.3.1.9.
//
ID   4.2.1.27
DE   Acetylenecarboxylate hydratase.
AN   Acetylenemonocarboxylate hydratase.
AN   Alkynoate hydratase.
AN   Malonate-semialdehyde dehydratase.
CA   3-oxopropanoate = propynoate + H(2)O.
CC   -!- The reaction is effectively irreversible, favoring oxopropanoate
CC       (malonic semialdehyde) and its tautomers.
CC   -!- Also acts on but-3-ynoate forming acetoacetate.
CC   -!- The mechanism appears to involve hydration of the acetylene to
CC       3-hydroxypropenoate, which will spontaneously tautomerize to
CC       3-oxopropanoate.
CC   -!- It is thus analogous to EC 4.1.1.78 in its mechanism.
CC   -!- Formerly EC 4.2.1.71.
//
ID   4.2.1.28
DE   Propanediol dehydratase.
CA   Propane-1,2-diol = propanal + H(2)O.
CF   Cobalamin.
CC   -!- Also dehydrates ethylene glycol to acetaldehyde.
DR   P37450, PDUC_SALTY ;  O31041, PDUD_SALTY ;  O31042, PDUE_SALTY ;
//
ID   4.2.1.29
DE   Transferred entry: 4.99.1.6.
//
ID   4.2.1.30
DE   Glycerol dehydratase.
CA   Glycerol = 3-hydroxypropanal + H(2)O.
CF   Cobalamin.
DR   P45514, DHAB_CITFR ;
//
ID   4.2.1.31
DE   Maleate hydratase.
CA   (R)-malate = maleate + H(2)O.
DR   P81291, LEUC_METJA ;  Q58673, LEUD_METJA ;
//
ID   4.2.1.32
DE   L(+)-tartrate dehydratase.
CA   (R,R)-tartrate = oxaloacetate + H(2)O.
CF   Iron.
CC   -!- Exists in an inactive low-molecular form, which is converted into
CC       active enzyme in the presence of Fe(2+) and thiol (cf. EC 4.2.1.81).
DR   Q8XBK7, TTDA_ECO57 ;  Q0TD45, TTDA_ECOL5 ;  Q8FDG8, TTDA_ECOL6 ;
DR   P05847, TTDA_ECOLI ;  Q1R6S0, TTDA_ECOUT ;  Q31WX3, TTDA_SHIBS ;
DR   Q83Q43, TTDA_SHIFL ;  Q3YXI2, TTDA_SHISS ;  Q8XBK5, TTDB_ECO57 ;
DR   Q0TD44, TTDB_ECOL5 ;  P0AC36, TTDB_ECOL6 ;  P0AC35, TTDB_ECOLI ;
DR   Q1R6R9, TTDB_ECOUT ;  Q31WX2, TTDB_SHIBS ;  P0AC37, TTDB_SHIFL ;
DR   Q3YXI1, TTDB_SHISS ;
//
ID   4.2.1.33
DE   3-isopropylmalate dehydratase.
AN   (2R,3S)-3-isopropylmalate hydro-lyase.
AN   3-isopropylmalate hydro-lyase.
AN   Alpha-IPM isomerase.
AN   Isopropylmalate isomerase.
CA   (1) (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmaleate + H(2)O.
CA   (2) (2S)-2-isopropylmaleate + H(2)O = (2S)-2-isopropylmalate.
CC   -!- Forms part of the leucine-biosynthesis pathway.
CC   -!- Brings about the interconversion of the two isomers of
CC       isopropylmalate.
PR   PROSITE; PDOC00423;
DR   O28316, LEUC1_ARCFU;  Q89X98, LEUC1_BRAJA;  Q9RTY9, LEUC1_DEIRA;
DR   Q65VS0, LEUC1_MANSM;  Q8TLF1, LEUC1_METAC;  Q8TVF2, LEUC1_METKA;
DR   Q8PZT3, LEUC1_METMA;  O27439, LEUC1_METTH;  Q9UZ07, LEUC1_PYRAB;
DR   Q8U2A1, LEUC1_PYRFU;  Q1AZC4, LEUC1_RUBXD;  Q57TE8, LEUC1_SALCH;
DR   P15717, LEUC1_SALTY;  Q9WYC7, LEUC1_THEMA;  O28084, LEUC2_ARCFU;
DR   Q89X34, LEUC2_BRAJA;  Q9RTI6, LEUC2_DEIRA;  Q65V07, LEUC2_MANSM;
DR   Q8TQZ3, LEUC2_METAC;  Q8TW29, LEUC2_METKA;  Q8PUG1, LEUC2_METMA;
DR   O27668, LEUC2_METTH;  Q9V1J0, LEUC2_PYRAB;  Q8U0C0, LEUC2_PYRFU;
DR   Q1AVC5, LEUC2_RUBXD;  Q57SN1, LEUC2_SALCH;  Q8ZRJ0, LEUC2_SALTY;
DR   Q9WZ24, LEUC2_THEMA;  B0CG35, LEUC_ACAM1 ;  A1TLH6, LEUC_ACIAC ;
DR   Q6FEW0, LEUC_ACIAD ;  B7H0T7, LEUC_ACIB3 ;  B7I4E1, LEUC_ACIB5 ;
DR   B2I359, LEUC_ACIBC ;  Q1IMI3, LEUC_ACIBL ;  A3M1S8, LEUC_ACIBT ;
DR   A0LVA3, LEUC_ACIC1 ;  C1F700, LEUC_ACIC5 ;  A5G0G6, LEUC_ACICJ ;
DR   B9MDK8, LEUC_ACIET ;  B7J5E0, LEUC_ACIF2 ;  B5ENJ1, LEUC_ACIF5 ;
DR   A1WAS7, LEUC_ACISJ ;  A3MYL1, LEUC_ACTP2 ;  B3GZY1, LEUC_ACTP7 ;
DR   B0BS44, LEUC_ACTPJ ;  A6VQL0, LEUC_ACTSZ ;  Q44427, LEUC_ACTTI ;
DR   A0KGM7, LEUC_AERHH ;  A4SR64, LEUC_AERS4 ;  B9JCN5, LEUC_AGRRK ;
DR   Q8UBY9, LEUC_AGRT5 ;  B9JUD6, LEUC_AGRVS ;  B2UPW8, LEUC_AKKM8 ;
DR   Q0VPI0, LEUC_ALCBS ;  Q0A9B0, LEUC_ALHEH ;  B6ELJ8, LEUC_ALISL ;
DR   B4RVU9, LEUC_ALTMD ;  B8J825, LEUC_ANAD2 ;  Q2IJC2, LEUC_ANADE ;
DR   A7HBI2, LEUC_ANADF ;  B4UAN0, LEUC_ANASK ;  B9MLV4, LEUC_ANATD ;
DR   Q3M614, LEUC_ANAVT ;  B7GH21, LEUC_ANOFW ;  O67078, LEUC_AQUAE ;
DR   Q94AR8, LEUC_ARATH ;  A8EQZ0, LEUC_ARCB4 ;  Q5P1J8, LEUC_AROAE ;
DR   A1R7K0, LEUC_ARTAT ;  B8HAC9, LEUC_ARTCA ;  A0JXX8, LEUC_ARTS2 ;
DR   Q74ZM9, LEUC_ASHGO ;  A1K4A1, LEUC_AZOSB ;  P96195, LEUC_AZOVI ;
DR   A7Z7B6, LEUC_BACA2 ;  C3P4Z8, LEUC_BACAA ;  C3L9Q5, LEUC_BACAC ;
DR   A0RBL4, LEUC_BACAH ;  Q81T66, LEUC_BACAN ;  B7JFY7, LEUC_BACC0 ;
DR   Q73B98, LEUC_BACC1 ;  B7IN95, LEUC_BACC2 ;  C1EMB1, LEUC_BACC3 ;
DR   B7HHF7, LEUC_BACC4 ;  B7HKC6, LEUC_BACC7 ;  A7GMU3, LEUC_BACCN ;
DR   B9IUZ2, LEUC_BACCQ ;  Q81G10, LEUC_BACCR ;  Q63DX6, LEUC_BACCZ ;
DR   Q5LAB1, LEUC_BACFN ;  Q64QP1, LEUC_BACFR ;  Q9K8F0, LEUC_BACHD ;
DR   Q6HLF1, LEUC_BACHK ;  Q65GJ0, LEUC_BACLD ;  A8FFW3, LEUC_BACP2 ;
DR   Q5WEN5, LEUC_BACSK ;  P80858, LEUC_BACSU ;  Q8A6L7, LEUC_BACTN ;
DR   A6L1V8, LEUC_BACV8 ;  A9VLG9, LEUC_BACWK ;  B8DVN0, LEUC_BIFA0 ;
DR   A0ZZS7, LEUC_BIFAA ;  B3DPI2, LEUC_BIFLD ;  Q8G4W2, LEUC_BIFLO ;
DR   B7GNM7, LEUC_BIFLS ;  Q7VQJ8, LEUC_BLOFL ;  Q493R2, LEUC_BLOPB ;
DR   Q7WKH6, LEUC_BORBR ;  Q7W931, LEUC_BORPA ;  Q7VY75, LEUC_BORPE ;
DR   B2S860, LEUC_BRUA1 ;  Q2YLP7, LEUC_BRUA2 ;  Q57AZ0, LEUC_BRUAB ;
DR   A9M8P2, LEUC_BRUC2 ;  C0RFF1, LEUC_BRUMB ;  Q8YJC9, LEUC_BRUME ;
DR   A5VSN3, LEUC_BRUO2 ;  B0CIF7, LEUC_BRUSI ;  Q8FYG9, LEUC_BRUSU ;
DR   P56934, LEUC_BUCAI ;  O85065, LEUC_BUCAP ;  P59519, LEUC_BUCBP ;
DR   Q5WPZ8, LEUC_BUCCC ;  O85072, LEUC_BUCDN ;  Q9EVG2, LEUC_BUCML ;
DR   P58945, LEUC_BUCPS ;  P48573, LEUC_BUCRP ;  O31293, LEUC_BUCTS ;
DR   Q9EVG5, LEUC_BUCUA ;  Q9EVE0, LEUC_BUCUD ;  Q9EVH4, LEUC_BUCUE ;
DR   Q9EVH7, LEUC_BUCUH ;  Q9AQC6, LEUC_BUCUL ;  Q9EVG8, LEUC_BUCUM ;
DR   Q9EVI6, LEUC_BUCUN ;  Q9EVI0, LEUC_BUCUO ;  Q9EVI3, LEUC_BUCUS ;
DR   B1Z1N0, LEUC_BURA4 ;  Q1BM55, LEUC_BURCA ;  B1K377, LEUC_BURCC ;
DR   A0AZ60, LEUC_BURCH ;  Q0BAC8, LEUC_BURCM ;  A3MBT5, LEUC_BURM7 ;
DR   A2S127, LEUC_BURM9 ;  Q62AI6, LEUC_BURMA ;  A1UZ32, LEUC_BURMS ;
DR   A3P7N9, LEUC_BURP0 ;  Q3JKG6, LEUC_BURP1 ;  A3NM77, LEUC_BURP6 ;
DR   B2JQE1, LEUC_BURP8 ;  Q63JK9, LEUC_BURPS ;  Q393X2, LEUC_BURS3 ;
DR   Q2T7H8, LEUC_BURTA ;  A4JMB6, LEUC_BURVG ;  A8MDY8, LEUC_CALMQ ;
DR   A4XJ48, LEUC_CALS8 ;  A7ZFP0, LEUC_CAMC1 ;  A7H0L8, LEUC_CAMC5 ;
DR   A0RMG7, LEUC_CAMFF ;  A7HZP6, LEUC_CAMHC ;  A8FP33, LEUC_CAMJ8 ;
DR   A7H665, LEUC_CAMJD ;  Q9PLW1, LEUC_CAMJE ;  A1W1X0, LEUC_CAMJJ ;
DR   Q5HS78, LEUC_CAMJR ;  Q00464, LEUC_CANMA ;  B8GY66, LEUC_CAUCN ;
DR   Q9ABN0, LEUC_CAUCR ;  B3PFN2, LEUC_CELJU ;  Q7NUB6, LEUC_CHRVO ;
DR   A8ALM7, LEUC_CITK8 ;  Q97EE0, LEUC_CLOAB ;  A6LPX4, LEUC_CLOB8 ;
DR   B2UYH6, LEUC_CLOBA ;  B2TIQ9, LEUC_CLOBB ;  Q18AJ2, LEUC_CLOD6 ;
DR   A5MZ75, LEUC_CLOK5 ;  A9KT79, LEUC_CLOPH ;  A3DHI4, LEUC_CLOTH ;
DR   Q47WG2, LEUC_COLP3 ;  Q6NHL0, LEUC_CORDI ;  Q8FPR3, LEUC_COREF ;
DR   A4QDS8, LEUC_CORGB ;  P58946, LEUC_CORGL ;  Q4JUX2, LEUC_CORJK ;
DR   Q44023, LEUC_CUPNE ;  Q46YV7, LEUC_CUPPJ ;  B1WZV3, LEUC_CYAA5 ;
DR   B8HLN1, LEUC_CYAP4 ;  B7KH96, LEUC_CYAP7 ;  B7K213, LEUC_CYAP8 ;
DR   Q11NN8, LEUC_CYTH3 ;  Q47HR4, LEUC_DECAR ;  B8FMM4, LEUC_DESAA ;
DR   B8J4F9, LEUC_DESDA ;  Q30WD3, LEUC_DESDG ;  Q24XT4, LEUC_DESHY ;
DR   A9A043, LEUC_DESOH ;  Q726X4, LEUC_DESVH ;  B8DM92, LEUC_DESVM ;
DR   A1VAE7, LEUC_DESVV ;  A8LKJ1, LEUC_DINSH ;  A7ZHG4, LEUC_ECO24 ;
DR   B7UIC2, LEUC_ECO27 ;  B7MAJ7, LEUC_ECO45 ;  B7L4J3, LEUC_ECO55 ;
DR   Q8XA00, LEUC_ECO57 ;  B5YZA8, LEUC_ECO5E ;  B7NHI0, LEUC_ECO7I ;
DR   B7MNT0, LEUC_ECO81 ;  B7M117, LEUC_ECO8A ;  C4ZPZ5, LEUC_ECOBW ;
DR   A7ZW23, LEUC_ECOHS ;  A1A7C0, LEUC_ECOK1 ;  Q0TLR7, LEUC_ECOL5 ;
DR   P0A6A7, LEUC_ECOL6 ;  B1IRA6, LEUC_ECOLC ;  P0A6A6, LEUC_ECOLI ;
DR   B7N7U7, LEUC_ECOLU ;  B6HZ52, LEUC_ECOSE ;  B1LG09, LEUC_ECOSM ;
DR   Q1RGC5, LEUC_ECOUT ;  C5B7R2, LEUC_EDWI9 ;  B2KBD7, LEUC_ELUMP ;
DR   A4W6H7, LEUC_ENT38 ;  A7MIC7, LEUC_ENTS8 ;  Q6D0G6, LEUC_ERWCT ;
DR   B7LWE0, LEUC_ESCF3 ;  A5FKC6, LEUC_FLAJ1 ;  Q0RDK7, LEUC_FRAAA ;
DR   Q2J6W9, LEUC_FRASC ;  A8L567, LEUC_FRASN ;  B5EHU2, LEUC_GEOBB ;
DR   Q5KWJ5, LEUC_GEOKA ;  Q39W70, LEUC_GEOMG ;  Q74BX5, LEUC_GEOSL ;
DR   C5D5L8, LEUC_GEOSW ;  A4IRH6, LEUC_GEOTN ;  A5G7U4, LEUC_GEOUR ;
DR   Q7NFV7, LEUC_GLOVI ;  Q5FUG3, LEUC_GLUOX ;  Q0BRH4, LEUC_GRABC ;
DR   Q4QLS2, LEUC_HAEI8 ;  A5UD83, LEUC_HAEIE ;  P44968, LEUC_HAEIN ;
DR   B8F3W8, LEUC_HAEPS ;  Q0I2G3, LEUC_HAES1 ;  B0USF4, LEUC_HAES2 ;
DR   Q2SJD8, LEUC_HAHCH ;  A1WY14, LEUC_HALHL ;  B9LUZ3, LEUC_HALLT ;
DR   Q5V518, LEUC_HALMA ;  B8CX22, LEUC_HALOH ;  Q7ZAG7, LEUC_HALVD ;
DR   Q7VH31, LEUC_HELHP ;  B0TCR2, LEUC_HELMI ;  A9B805, LEUC_HERA2 ;
DR   A4G4F5, LEUC_HERAR ;  B4U7U5, LEUC_HYDS0 ;  A6T015, LEUC_JANMA ;
DR   Q28W60, LEUC_JANSC ;  A6W7Q7, LEUC_KINRD ;  B5Y1W4, LEUC_KLEP3 ;
DR   A6T4L7, LEUC_KLEP7 ;  B2GCB8, LEUC_LACF3 ;  Q02142, LEUC_LACLA ;
DR   A2RKR3, LEUC_LACLM ;  Q02YY1, LEUC_LACLS ;  C1DD59, LEUC_LARHH ;
DR   Q6AFK7, LEUC_LEIXX ;  Q72RC4, LEUC_LEPIC ;  Q8F4E6, LEUC_LEPIN ;
DR   B1MVR0, LEUC_LEUCK ;  Q03UM2, LEUC_LEUMM ;  Q92A26, LEUC_LISIN ;
DR   C1KWT3, LEUC_LISMC ;  Q71Y33, LEUC_LISMF ;  B8DBU2, LEUC_LISMH ;
DR   Q8Y5R7, LEUC_LISMO ;  A0AK94, LEUC_LISW6 ;  B1HR96, LEUC_LYSSC ;
DR   Q2VZV4, LEUC_MAGSA ;  A0L8J4, LEUC_MAGSM ;  A1U0Y0, LEUC_MARAV ;
DR   Q0AT09, LEUC_MARMM ;  A6VX34, LEUC_MARMS ;  Q11CQ6, LEUC_MESSB ;
DR   A7IA28, LEUC_METB6 ;  B7KRK4, LEUC_METC4 ;  Q606F2, LEUC_METCA ;
DR   Q1H0L4, LEUC_METFK ;  P81291, LEUC_METJA ;  B1ZKX6, LEUC_METPB ;
DR   B1LXK9, LEUC_METRJ ;  A4YF03, LEUC_METS5 ;  B8EN95, LEUC_METSB ;
DR   B0JY97, LEUC_MICAN ;  Q2RG98, LEUC_MOOTA ;  A0QJB7, LEUC_MYCA1 ;
DR   B1MDQ1, LEUC_MYCA9 ;  Q7TXH6, LEUC_MYCBO ;  A1KMY2, LEUC_MYCBP ;
DR   C1AGA3, LEUC_MYCBT ;  A4TE23, LEUC_MYCGI ;  O33123, LEUC_MYCLE ;
DR   B2HII1, LEUC_MYCMM ;  Q73VI7, LEUC_MYCPA ;  Q938C9, LEUC_MYCS2 ;
DR   A3PXR2, LEUC_MYCSJ ;  A1UEA8, LEUC_MYCSK ;  Q1BAQ4, LEUC_MYCSS ;
DR   A5U6Z9, LEUC_MYCTA ;  O53237, LEUC_MYCTU ;  A0PPZ6, LEUC_MYCUA ;
DR   A1T700, LEUC_MYCVP ;  Q3IRQ4, LEUC_NATPD ;  B9L6Y8, LEUC_NAUPA ;
DR   Q5F8T1, LEUC_NEIG1 ;  B4RM67, LEUC_NEIG2 ;  A9LZF7, LEUC_NEIM0 ;
DR   Q9JU82, LEUC_NEIMA ;  Q9JZI5, LEUC_NEIMB ;  A1KU80, LEUC_NEIMF ;
DR   Q82WI9, LEUC_NITEU ;  Q1QHI4, LEUC_NITHX ;  Q3J716, LEUC_NITOC ;
DR   A6Q5L6, LEUC_NITSB ;  Q3SNV3, LEUC_NITWN ;  Q5YRY0, LEUC_NOCFA ;
DR   A1SLW5, LEUC_NOCSJ ;  B2J3M9, LEUC_NOSP7 ;  Q8YX02, LEUC_NOSS1 ;
DR   Q2G958, LEUC_NOVAD ;  Q8EN69, LEUC_OCEIH ;  A6WXG4, LEUC_OCHA4 ;
DR   Q04DA3, LEUC_OENOB ;  B6JAQ9, LEUC_OLICO ;  B1ZUZ1, LEUC_OPITP ;
DR   A1B513, LEUC_PARDP ;  A7HT10, LEUC_PARL1 ;  Q9CJN7, LEUC_PASMU ;
DR   C6DEW0, LEUC_PECCP ;  Q4FP15, LEUC_PELUB ;  B4RCC2, LEUC_PHEZH ;
DR   Q7N127, LEUC_PHOLL ;  Q6LV26, LEUC_PHOPR ;  P18250, LEUC_PHYBL ;
DR   Q6L0K5, LEUC_PICTO ;  A1VRR0, LEUC_POLNA ;  B1XV55, LEUC_POLNS ;
DR   Q126M9, LEUC_POLSJ ;  A4SWW8, LEUC_POLSQ ;  A3PAX7, LEUC_PROM0 ;
DR   A2C088, LEUC_PROM1 ;  A8G2R6, LEUC_PROM2 ;  A2CCJ0, LEUC_PROM3 ;
DR   A9BDM7, LEUC_PROM4 ;  A2BUN7, LEUC_PROM5 ;  Q31CS6, LEUC_PROM9 ;
DR   Q7VDT0, LEUC_PROMA ;  B4F196, LEUC_PROMH ;  Q7V4U5, LEUC_PROMM ;
DR   Q7V336, LEUC_PROMP ;  A2BP55, LEUC_PROMS ;  Q46HB8, LEUC_PROMT ;
DR   Q48K99, LEUC_PSE14 ;  Q15QR2, LEUC_PSEA6 ;  A6V2V3, LEUC_PSEA7 ;
DR   B7VBP9, LEUC_PSEA8 ;  Q02PT4, LEUC_PSEAB ;  Q9HZA3, LEUC_PSEAE ;
DR   Q1ICW0, LEUC_PSEE4 ;  Q4KF08, LEUC_PSEF5 ;  Q3IJS4, LEUC_PSEHT ;
DR   A4XVW2, LEUC_PSEMY ;  B0KF81, LEUC_PSEPG ;  Q88LE8, LEUC_PSEPK ;
DR   B1J530, LEUC_PSEPW ;  Q884C2, LEUC_PSESM ;  Q4ZUZ6, LEUC_PSEU2 ;
DR   A4VKE7, LEUC_PSEU5 ;  Q4FRU7, LEUC_PSYA2 ;  Q1QAF2, LEUC_PSYCK ;
DR   A1SVE7, LEUC_PSYIN ;  A5WGT5, LEUC_PSYWF ;  Q8ZW41, LEUC_PYRAE ;
DR   A4WMI6, LEUC_PYRAR ;  A3MWJ4, LEUC_PYRCJ ;  O59391, LEUC_PYRHO ;
DR   A1RVH3, LEUC_PYRIL ;  Q5JFV6, LEUC_PYRKO ;  Q8XXX3, LEUC_RALSO ;
DR   B3PR22, LEUC_RHIE6 ;  Q2K376, LEUC_RHIEC ;  Q1MAJ9, LEUC_RHIL3 ;
DR   Q98EF1, LEUC_RHILO ;  B5ZTI5, LEUC_RHILW ;  Q92L76, LEUC_RHIME ;
DR   P55811, LEUC_RHINI ;  P55251, LEUC_RHIPU ;  P17279, LEUC_RHIRA ;
DR   C3M9V0, LEUC_RHISN ;  Q7UIA7, LEUC_RHOBA ;  Q2J3A1, LEUC_RHOP2 ;
DR   Q07UU3, LEUC_RHOP5 ;  Q6ND69, LEUC_RHOPA ;  Q21CT4, LEUC_RHOPB ;
DR   Q13DU7, LEUC_RHOPS ;  B3Q851, LEUC_RHOPT ;  Q2RV55, LEUC_RHORT ;
DR   A3PMQ9, LEUC_RHOS1 ;  Q3IZI8, LEUC_RHOS4 ;  A4WNV5, LEUC_RHOS5 ;
DR   B9KMK4, LEUC_RHOSK ;  A7NJH2, LEUC_ROSCS ;  Q16CH7, LEUC_ROSDO ;
DR   A5UUP5, LEUC_ROSS1 ;  A1AW36, LEUC_RUTMC ;  Q21IY3, LEUC_SACD2 ;
DR   A4FMP2, LEUC_SACEN ;  B5F7U7, LEUC_SALA4 ;  A8M5I3, LEUC_SALAI ;
DR   A9MQE0, LEUC_SALAR ;  Q5PDG3, LEUC_SALPA ;  B5BLB3, LEUC_SALPK ;
DR   Q2S0M6, LEUC_SALRD ;  B4TWV9, LEUC_SALSV ;  Q8Z9I2, LEUC_SALTI ;
DR   A4X4C8, LEUC_SALTO ;  O14289, LEUC_SCHPO ;  A8G9Q9, LEUC_SERP5 ;
DR   A1S2E2, LEUC_SHEAM ;  B8E4K6, LEUC_SHEB2 ;  A3CZK7, LEUC_SHEB5 ;
DR   A6WIB7, LEUC_SHEB8 ;  A9KY15, LEUC_SHEB9 ;  Q07WH1, LEUC_SHEFN ;
DR   B0TQM2, LEUC_SHEHH ;  A3QIN8, LEUC_SHELP ;  Q8E9N4, LEUC_SHEON ;
DR   A8H999, LEUC_SHEPA ;  A4Y2M2, LEUC_SHEPC ;  B8CM41, LEUC_SHEPW ;
DR   A0L1Q8, LEUC_SHESA ;  A8FQ85, LEUC_SHESH ;  Q0HE67, LEUC_SHESM ;
DR   Q0HZT2, LEUC_SHESR ;  A1REY2, LEUC_SHESW ;  B1KKZ2, LEUC_SHEWM ;
DR   B2U279, LEUC_SHIB3 ;  Q326G3, LEUC_SHIBS ;  Q32K22, LEUC_SHIDS ;
DR   Q0T8C6, LEUC_SHIF8 ;  Q821C2, LEUC_SHIFL ;  Q3Z5T8, LEUC_SHISS ;
DR   Q5LX06, LEUC_SILPO ;  Q1GDM6, LEUC_SILST ;  A6UE05, LEUC_SINMW ;
DR   Q2NVW5, LEUC_SODGM ;  Q01Z81, LEUC_SOLUE ;  A9GL99, LEUC_SORC5 ;
DR   Q1GR84, LEUC_SPHAL ;  A7X4N3, LEUC_STAA1 ;  A6U3E4, LEUC_STAA2 ;
DR   Q2FF65, LEUC_STAA3 ;  Q2FWK1, LEUC_STAA8 ;  A5IUK5, LEUC_STAA9 ;
DR   Q2YUF0, LEUC_STAAB ;  Q5HEE2, LEUC_STAAC ;  A6QIQ5, LEUC_STAAE ;
DR   P63435, LEUC_STAAM ;  P63436, LEUC_STAAN ;  Q6GF14, LEUC_STAAR ;
DR   Q6G7P9, LEUC_STAAS ;  A8Z4W2, LEUC_STAAT ;  P58947, LEUC_STAAW ;
DR   B9DMJ8, LEUC_STACT ;  Q5HMF7, LEUC_STAEQ ;  Q8CNL1, LEUC_STAES ;
DR   Q4L7U2, LEUC_STAHJ ;  Q49Z14, LEUC_STAS1 ;  Q82JR8, LEUC_STRAW ;
DR   O86534, LEUC_STRCO ;  A8AWP5, LEUC_STRGC ;  B1VZ03, LEUC_STRGG ;
DR   Q9AIM3, LEUC_STRGN ;  Q8DTG4, LEUC_STRMU ;  A3CMJ2, LEUC_STRSV ;
DR   Q5LZF4, LEUC_STRT1 ;  Q5M406, LEUC_STRT2 ;  Q03KB3, LEUC_STRTD ;
DR   Q4JC09, LEUC_SULAC ;  Q30NZ0, LEUC_SULDN ;  A6Q6J8, LEUC_SULNB ;
DR   Q97VY2, LEUC_SULSO ;  B2V844, LEUC_SULSY ;  Q974R0, LEUC_SULTO ;
DR   Q67MJ2, LEUC_SYMTH ;  Q2LWJ2, LEUC_SYNAS ;  Q31LZ1, LEUC_SYNE7 ;
DR   Q2JQU3, LEUC_SYNJA ;  Q2JPG2, LEUC_SYNJB ;  B1XLQ6, LEUC_SYNP2 ;
DR   Q5MZY3, LEUC_SYNP6 ;  A5GIG7, LEUC_SYNPW ;  Q7U9J4, LEUC_SYNPX ;
DR   A5GWH5, LEUC_SYNR3 ;  Q0IDD5, LEUC_SYNS3 ;  Q3AW21, LEUC_SYNS9 ;
DR   Q3AN00, LEUC_SYNSC ;  P54384, LEUC_SYNY3 ;  C5BL66, LEUC_TERTT ;
DR   Q8DKF0, LEUC_THEEB ;  Q47SA3, LEUC_THEFY ;  B1YD98, LEUC_THENV ;
DR   B0KAH5, LEUC_THEP3 ;  B0K0Y2, LEUC_THEPX ;  Q72JB3, LEUC_THET2 ;
DR   Q9ZND5, LEUC_THET8 ;  Q8RDK2, LEUC_THETN ;  B5YKE0, LEUC_THEYD ;
DR   Q31HI2, LEUC_THICR ;  Q3SHL1, LEUC_THIDA ;  B8GQD6, LEUC_THISH ;
DR   C4LAV5, LEUC_TOLAT ;  B1H0A6, LEUC_UNCTG ;  P49601, LEUC_USTMA ;
DR   C5CSH5, LEUC_VARPS ;  A5CX27, LEUC_VESOH ;  A5F5E2, LEUC_VIBC3 ;
DR   Q9KP81, LEUC_VIBCH ;  C3LR34, LEUC_VIBCM ;  Q5E858, LEUC_VIBF1 ;
DR   B5FGH2, LEUC_VIBFM ;  A7MWC3, LEUC_VIBHB ;  Q87SS9, LEUC_VIBPA ;
DR   Q8DED9, LEUC_VIBVU ;  Q7MP79, LEUC_VIBVY ;  Q7M9Z9, LEUC_WOLSU ;
DR   P58948, LEUC_XANAC ;  Q3BPJ6, LEUC_XANC5 ;  Q4UYG5, LEUC_XANC8 ;
DR   P58949, LEUC_XANCP ;  Q2P765, LEUC_XANOM ;  B2SNH4, LEUC_XANOP ;
DR   Q5H4D1, LEUC_XANOR ;  B2I6I6, LEUC_XYLF2 ;  Q9PAX0, LEUC_XYLFA ;
DR   B0U3M6, LEUC_XYLFM ;  Q87BP9, LEUC_XYLFT ;  P07264, LEUC_YEAST ;
DR   A1JJH5, LEUC_YERE8 ;  A7FM86, LEUC_YERP3 ;  Q1C1Z4, LEUC_YERPA ;
DR   B2K4C7, LEUC_YERPB ;  Q8ZIH0, LEUC_YERPE ;  A9R144, LEUC_YERPG ;
DR   Q1CMP7, LEUC_YERPN ;  A4TQA4, LEUC_YERPP ;  Q66EM3, LEUC_YERPS ;
DR   B1JKA0, LEUC_YERPY ;  Q5NRC5, LEUC_ZYMMO ;  O29626, LEUD1_ARCFU;
DR   Q7WKH5, LEUD1_BORBR;  Q7W930, LEUD1_BORPA;  Q7VYI1, LEUD1_BORPE;
DR   Q7NW22, LEUD1_CHRVO;  Q9RTY5, LEUD1_DEIRA;  Q65VR9, LEUD1_MANSM;
DR   Q8TJM9, LEUD1_METAC;  Q8TX94, LEUD1_METKA;  Q8PZ49, LEUD1_METMA;
DR   O26917, LEUD1_METTH;  Q9UZ06, LEUD1_PYRAB;  Q8U2A0, LEUD1_PYRFU;
DR   Q57TE9, LEUD1_SALCH;  P04787, LEUD1_SALTY;  Q9WYC8, LEUD1_THEMA;
DR   O28513, LEUD2_ARCFU;  Q7WIN3, LEUD2_BORBR;  Q7W749, LEUD2_BORPA;
DR   Q7VY74, LEUD2_BORPE;  Q7NUB8, LEUD2_CHRVO;  Q9RTI0, LEUD2_DEIRA;
DR   Q65V08, LEUD2_MANSM;  Q8TU71, LEUD2_METAC;  Q8TW31, LEUD2_METKA;
DR   Q8PWT6, LEUD2_METMA;  O27440, LEUD2_METTH;  Q9V1I9, LEUD2_PYRAB;
DR   Q8U0B9, LEUD2_PYRFU;  Q57SN0, LEUD2_SALCH;  Q8ZRI9, LEUD2_SALTY;
DR   Q9WZ25, LEUD2_THEMA;  Q8TRF7, LEUD3_METAC;  A1TLH5, LEUD_ACIAC ;
DR   Q6FEV8, LEUD_ACIAD ;  B7H0T6, LEUD_ACIB3 ;  B7I4E2, LEUD_ACIB5 ;
DR   B2I360, LEUD_ACIBC ;  Q1IMI4, LEUD_ACIBL ;  B0VLB1, LEUD_ACIBS ;
DR   A3M1S9, LEUD_ACIBT ;  B0V4L7, LEUD_ACIBY ;  A0LVA2, LEUD_ACIC1 ;
DR   C1F6Z9, LEUD_ACIC5 ;  B9MDL1, LEUD_ACIET ;  B7J5S3, LEUD_ACIF2 ;
DR   B5ENJ2, LEUD_ACIF5 ;  A1WAT0, LEUD_ACISJ ;  A3MYL0, LEUD_ACTP2 ;
DR   B3GZY0, LEUD_ACTP7 ;  B0BS43, LEUD_ACTPJ ;  A6VQL1, LEUD_ACTSZ ;
DR   Q44428, LEUD_ACTTI ;  A0KGM6, LEUD_AERHH ;  A4SR65, LEUD_AERS4 ;
DR   B9JET5, LEUD_AGRRK ;  Q8UBR0, LEUD_AGRT5 ;  B9JV26, LEUD_AGRVS ;
DR   Q0VPI1, LEUD_ALCBS ;  Q0A9A9, LEUD_ALHEH ;  B6ELJ7, LEUD_ALISL ;
DR   B8J826, LEUD_ANAD2 ;  Q2IJC3, LEUD_ANADE ;  A7HBI3, LEUD_ANADF ;
DR   B4UAN1, LEUD_ANASK ;  B9MLV3, LEUD_ANATD ;  B7GH22, LEUD_ANOFW ;
DR   O67399, LEUD_AQUAE ;  A8ETJ8, LEUD_ARCB4 ;  Q5P1J7, LEUD_AROAE ;
DR   A1R7J9, LEUD_ARTAT ;  B8HAC8, LEUD_ARTCA ;  A0JXX7, LEUD_ARTS2 ;
DR   A8ILN3, LEUD_AZOC5 ;  B6YRN2, LEUD_AZOPC ;  A1K4A2, LEUD_AZOSB ;
DR   P96196, LEUD_AZOVI ;  A7Z7B5, LEUD_BACA2 ;  C3P4Z9, LEUD_BACAA ;
DR   C3L9Q4, LEUD_BACAC ;  Q81T65, LEUD_BACAN ;  B7JFY8, LEUD_BACC0 ;
DR   Q73B97, LEUD_BACC1 ;  C1EMB2, LEUD_BACC3 ;  B7HHF8, LEUD_BACC4 ;
DR   B7HKC7, LEUD_BACC7 ;  A7GMU4, LEUD_BACCN ;  B9IUZ3, LEUD_BACCQ ;
DR   Q81G09, LEUD_BACCR ;  Q63DX5, LEUD_BACCZ ;  Q9K8F1, LEUD_BACHD ;
DR   Q6HLF0, LEUD_BACHK ;  Q65GJ1, LEUD_BACLD ;  A8FFW2, LEUD_BACP2 ;
DR   Q5WEN6, LEUD_BACSK ;  P94568, LEUD_BACSU ;  C5C3D1, LEUD_BEUC1 ;
DR   B8DVN1, LEUD_BIFA0 ;  A0ZZS8, LEUD_BIFAA ;  B3DPI3, LEUD_BIFLD ;
DR   Q8G4W1, LEUD_BIFLO ;  B7GNM6, LEUD_BIFLS ;  Q7VQJ9, LEUD_BLOFL ;
DR   Q493R3, LEUD_BLOPB ;  Q2KYL4, LEUD_BORA1 ;  C0R087, LEUD_BRAHW ;
DR   Q89X27, LEUD_BRAJA ;  A5E8Z8, LEUD_BRASB ;  C0ZCK0, LEUD_BREBN ;
DR   B2SAF6, LEUD_BRUA1 ;  Q2YL51, LEUD_BRUA2 ;  Q579A4, LEUD_BRUAB ;
DR   A9MCG4, LEUD_BRUC2 ;  C0RM30, LEUD_BRUMB ;  P65275, LEUD_BRUME ;
DR   A9WVP8, LEUD_BRUSI ;  P65276, LEUD_BRUSU ;  P56935, LEUD_BUCAI ;
DR   O85066, LEUD_BUCAP ;  P59516, LEUD_BUCBP ;  O85073, LEUD_BUCDN ;
DR   Q9ZEZ5, LEUD_BUCPP ;  P59019, LEUD_BUCPS ;  P48574, LEUD_BUCRP ;
DR   O31294, LEUD_BUCTS ;  B1Z1N2, LEUD_BURA4 ;  B1K375, LEUD_BURCC ;
DR   Q0BAC6, LEUD_BURCM ;  A9AMB3, LEUD_BURM1 ;  A3MBT7, LEUD_BURM7 ;
DR   A2S129, LEUD_BURM9 ;  Q62AI8, LEUD_BURMA ;  A1UZ33, LEUD_BURMS ;
DR   A3P7N7, LEUD_BURP0 ;  Q3JKG8, LEUD_BURP1 ;  A3NM75, LEUD_BURP6 ;
DR   B2JQE2, LEUD_BURP8 ;  Q63JL1, LEUD_BURPS ;  Q2T7H7, LEUD_BURTA ;
DR   A4XJ49, LEUD_CALS8 ;  A8FP32, LEUD_CAMJ8 ;  A7H664, LEUD_CAMJD ;
DR   Q9PLW2, LEUD_CAMJE ;  A1W1W9, LEUD_CAMJJ ;  Q5HS79, LEUD_CAMJR ;
DR   B8GY65, LEUD_CAUCN ;  Q9ABN1, LEUD_CAUCR ;  B0T3B7, LEUD_CAUSK ;
DR   B3PFN3, LEUD_CELJU ;  A9WC30, LEUD_CHLAA ;  B8G7X5, LEUD_CHLAD ;
DR   B9LGN1, LEUD_CHLSY ;  Q1QUQ9, LEUD_CHRSD ;  A8ALM8, LEUD_CITK8 ;
DR   A5CQN3, LEUD_CLAM3 ;  B0REY1, LEUD_CLAMS ;  Q97EE1, LEUD_CLOAB ;
DR   A6LPX5, LEUD_CLOB8 ;  B2UYT4, LEUD_CLOBA ;  B2TIR0, LEUD_CLOBB ;
DR   B8I4G1, LEUD_CLOCE ;  Q18AJ1, LEUD_CLOD6 ;  P31960, LEUD_CLOPA ;
DR   A9KT78, LEUD_CLOPH ;  Q47WG1, LEUD_COLP3 ;  C3PFZ5, LEUD_CORA7 ;
DR   Q6NHK9, LEUD_CORDI ;  Q8FPR2, LEUD_COREF ;  A4QDS9, LEUD_CORGB ;
DR   Q8NQV7, LEUD_CORGL ;  Q4JUX3, LEUD_CORJK ;  C4LJF0, LEUD_CORK4 ;
DR   Q44022, LEUD_CUPNE ;  Q46YV9, LEUD_CUPPJ ;  Q11NN7, LEUD_CYTH3 ;
DR   Q47HR2, LEUD_DECAR ;  C1CVE0, LEUD_DEIDV ;  A9BNH1, LEUD_DELAS ;
DR   C6BSH0, LEUD_DESAD ;  C0QDY4, LEUD_DESAH ;  B8J4G0, LEUD_DESDA ;
DR   Q30WD2, LEUD_DESDG ;  Q726X3, LEUD_DESVH ;  A1VAE6, LEUD_DESVV ;
DR   A8LKI9, LEUD_DINSH ;  A7ZHG3, LEUD_ECO24 ;  B7UIC1, LEUD_ECO27 ;
DR   B7MAJ6, LEUD_ECO45 ;  B7L4J2, LEUD_ECO55 ;  Q8XA01, LEUD_ECO57 ;
DR   B5YZA7, LEUD_ECO5E ;  B7NHH9, LEUD_ECO7I ;  B7MNS9, LEUD_ECO81 ;
DR   B7M116, LEUD_ECO8A ;  C4ZPZ4, LEUD_ECOBW ;  A7ZW22, LEUD_ECOHS ;
DR   A1A7B9, LEUD_ECOK1 ;  Q0TLR8, LEUD_ECOL5 ;  Q8FL79, LEUD_ECOL6 ;
DR   B1IRA7, LEUD_ECOLC ;  P30126, LEUD_ECOLI ;  B7N7U6, LEUD_ECOLU ;
DR   B6HZ51, LEUD_ECOSE ;  B1LG08, LEUD_ECOSM ;  Q1RGC6, LEUD_ECOUT ;
DR   C5B7R1, LEUD_EDWI9 ;  A4W6H6, LEUD_ENT38 ;  A7MQ53, LEUD_ENTS8 ;
DR   Q6D0G5, LEUD_ERWCT ;  B2VDA2, LEUD_ERWT9 ;  Q2NC39, LEUD_ERYLH ;
DR   B7LWD9, LEUD_ESCF3 ;  C4Z1K1, LEUD_EUBE2 ;  Q0RDK8, LEUD_FRAAA ;
DR   B0TW84, LEUD_FRAP2 ;  Q2J6X0, LEUD_FRASC ;  A8L568, LEUD_FRASN ;
DR   A7NES0, LEUD_FRATF ;  Q2A1A1, LEUD_FRATH ;  A0Q406, LEUD_FRATN ;
DR   Q0BK19, LEUD_FRATO ;  Q5KWJ6, LEUD_GEOKA ;  C5D5L7, LEUD_GEOSW ;
DR   A9HS54, LEUD_GLUDA ;  Q5FUG4, LEUD_GLUOX ;  Q0BRH5, LEUD_GRABC ;
DR   A0M367, LEUD_GRAFK ;  Q4QLS1, LEUD_HAEI8 ;  A5UD82, LEUD_HAEIE ;
DR   A5UIC6, LEUD_HAEIG ;  P44438, LEUD_HAEIN ;  B8F3W7, LEUD_HAEPS ;
DR   Q0I2G4, LEUD_HAES1 ;  B0USF3, LEUD_HAES2 ;  Q2SJD7, LEUD_HAHCH ;
DR   B8CX23, LEUD_HALOH ;  Q7VH32, LEUD_HELHP ;  B0TCR3, LEUD_HELMI ;
DR   A9AZ32, LEUD_HERA2 ;  B4U7M0, LEUD_HYDS0 ;  Q28W72, LEUD_JANSC ;
DR   A6W7Q8, LEUD_KINRD ;  B5Y1W5, LEUD_KLEP3 ;  A6T4L6, LEUD_KLEP7 ;
DR   B2GFK7, LEUD_KOCRD ;  B2GCB7, LEUD_LACF3 ;  Q02144, LEUD_LACLA ;
DR   A2RKR1, LEUD_LACLM ;  C1DD62, LEUD_LARHH ;  Q6AFK6, LEUD_LEIXX ;
DR   Q04RN8, LEUD_LEPBJ ;  Q051Y3, LEUD_LEPBL ;  B1XY42, LEUD_LEPCP ;
DR   Q72RC5, LEUD_LEPIC ;  Q8F4E5, LEUD_LEPIN ;  B1MVQ9, LEUD_LEUCK ;
DR   Q03UM3, LEUD_LEUMM ;  Q92A25, LEUD_LISIN ;  C1KWT4, LEUD_LISMC ;
DR   Q71Y32, LEUD_LISMF ;  B8DBU1, LEUD_LISMH ;  Q8Y5R6, LEUD_LISMO ;
DR   A0AK95, LEUD_LISW6 ;  Q2VZV3, LEUD_MAGSA ;  A0L8J5, LEUD_MAGSM ;
DR   A1U0X9, LEUD_MARAV ;  A6VX35, LEUD_MARMS ;  B7KZ04, LEUD_METC4 ;
DR   Q606F3, LEUD_METCA ;  Q8RP98, LEUD_METEA ;  A9VZG4, LEUD_METEP ;
DR   Q1H0L5, LEUD_METFK ;  Q58673, LEUD_METJA ;  B1ZI64, LEUD_METPB ;
DR   A2SHT0, LEUD_METPP ;  B1LZS5, LEUD_METRJ ;  A4YF02, LEUD_METS5 ;
DR   B8ENI5, LEUD_METSB ;  C5CAC9, LEUD_MICLC ;  Q2RG99, LEUD_MOOTA ;
DR   A0QJB6, LEUD_MYCA1 ;  B1MDQ0, LEUD_MYCA9 ;  P65278, LEUD_MYCBO ;
DR   A1KMY1, LEUD_MYCBP ;  C1AGA2, LEUD_MYCBT ;  A4TE22, LEUD_MYCGI ;
DR   B8ZS11, LEUD_MYCLB ;  O33124, LEUD_MYCLE ;  B2HII2, LEUD_MYCMM ;
DR   Q73VI8, LEUD_MYCPA ;  Q938C8, LEUD_MYCS2 ;  A3PXR3, LEUD_MYCSJ ;
DR   A1UEA9, LEUD_MYCSK ;  Q1BAQ3, LEUD_MYCSS ;  A5U6Z8, LEUD_MYCTA ;
DR   P65277, LEUD_MYCTU ;  A0PPZ7, LEUD_MYCUA ;  A1T701, LEUD_MYCVP ;
DR   B9L5K2, LEUD_NAUPA ;  Q5F8T3, LEUD_NEIG1 ;  Q50974, LEUD_NEIGO ;
DR   P50181, LEUD_NEILA ;  A9LZF9, LEUD_NEIM0 ;  Q9JU81, LEUD_NEIMA ;
DR   Q9JZI6, LEUD_NEIMB ;  A1KU82, LEUD_NEIMF ;  Q0AGY1, LEUD_NITEC ;
DR   Q82WI7, LEUD_NITEU ;  Q1QHH8, LEUD_NITHX ;  Q3JCC5, LEUD_NITOC ;
DR   Q3SNU7, LEUD_NITWN ;  Q5YRY1, LEUD_NOCFA ;  A1SLW4, LEUD_NOCSJ ;
DR   Q8YX03, LEUD_NOSS1 ;  Q2G955, LEUD_NOVAD ;  Q8EN70, LEUD_OCEIH ;
DR   A6X449, LEUD_OCHA4 ;  Q04DA2, LEUD_OENOB ;  B6JAR2, LEUD_OLICO ;
DR   Q9LCR5, LEUD_PAEPO ;  A1B515, LEUD_PARDP ;  A7HT11, LEUD_PARL1 ;
DR   Q9CJN8, LEUD_PASMU ;  C6DEW1, LEUD_PECCP ;  Q4FP16, LEUD_PELUB ;
DR   B4RCC0, LEUD_PHEZH ;  Q7N126, LEUD_PHOLL ;  Q6LV27, LEUD_PHOPR ;
DR   A1VRR1, LEUD_POLNA ;  B1XV53, LEUD_POLNS ;  Q126M8, LEUD_POLSJ ;
DR   A4SWX0, LEUD_POLSQ ;  B4F197, LEUD_PROMH ;  Q48K98, LEUD_PSE14 ;
DR   A6V2V4, LEUD_PSEA7 ;  B7VBQ0, LEUD_PSEA8 ;  Q02PT3, LEUD_PSEAB ;
DR   Q9HZA4, LEUD_PSEAE ;  Q1ICV9, LEUD_PSEE4 ;  Q4KF07, LEUD_PSEF5 ;
DR   Q3IJS5, LEUD_PSEHT ;  A4XVW1, LEUD_PSEMY ;  B0KF82, LEUD_PSEPG ;
DR   Q88LE7, LEUD_PSEPK ;  B1J531, LEUD_PSEPW ;  Q884C1, LEUD_PSESM ;
DR   Q4ZUZ5, LEUD_PSEU2 ;  A4VKE8, LEUD_PSEU5 ;  Q4FRU8, LEUD_PSYA2 ;
DR   Q1QAF3, LEUD_PSYCK ;  A1SVE8, LEUD_PSYIN ;  A5WGT4, LEUD_PSYWF ;
DR   Q8ZW36, LEUD_PYRAE ;  A3MWK3, LEUD_PYRCJ ;  O59393, LEUD_PYRHO ;
DR   A1RVI0, LEUD_PYRIL ;  Q5JFV7, LEUD_PYRKO ;  Q8XXX4, LEUD_RALSO ;
DR   B3PS18, LEUD_RHIE6 ;  Q2K2V2, LEUD_RHIEC ;  Q1MA52, LEUD_RHIL3 ;
DR   Q98E51, LEUD_RHILO ;  B5ZV14, LEUD_RHILW ;  Q92LA1, LEUD_RHIME ;
DR   C3M9W6, LEUD_RHISN ;  Q7UIA6, LEUD_RHOBA ;  B6IYC9, LEUD_RHOCS ;
DR   C0ZXN2, LEUD_RHOE4 ;  Q21XI0, LEUD_RHOFD ;  Q2J3A7, LEUD_RHOP2 ;
DR   Q07UT6, LEUD_RHOP5 ;  Q6ND74, LEUD_RHOPA ;  Q21CT1, LEUD_RHOPB ;
DR   Q13DV3, LEUD_RHOPS ;  B3Q845, LEUD_RHOPT ;  Q2RV54, LEUD_RHORT ;
DR   A3PMQ7, LEUD_RHOS1 ;  Q3IZJ0, LEUD_RHOS4 ;  A4WNV6, LEUD_RHOS5 ;
DR   B9KMK2, LEUD_RHOSK ;  A7NJH1, LEUD_ROSCS ;  Q16DI8, LEUD_ROSDO ;
DR   A5UUP4, LEUD_ROSS1 ;  Q1AZC3, LEUD_RUBXD ;  A1AW35, LEUD_RUTMC ;
DR   Q21IY4, LEUD_SACD2 ;  A4FMP1, LEUD_SACEN ;  A8M5I4, LEUD_SALAI ;
DR   A9MQE1, LEUD_SALAR ;  Q5PDG4, LEUD_SALPA ;  B5BLB2, LEUD_SALPK ;
DR   B4TWV8, LEUD_SALSV ;  Q8Z9I3, LEUD_SALTI ;  A4X4C9, LEUD_SALTO ;
DR   A8G9Q8, LEUD_SERP5 ;  A1S2E3, LEUD_SHEAM ;  B8E4K7, LEUD_SHEB2 ;
DR   A3CZK8, LEUD_SHEB5 ;  A6WIB8, LEUD_SHEB8 ;  A9KY16, LEUD_SHEB9 ;
DR   Q12SE4, LEUD_SHEDO ;  Q07WH2, LEUD_SHEFN ;  B0TQM3, LEUD_SHEHH ;
DR   A3QIN7, LEUD_SHELP ;  Q8E9N5, LEUD_SHEON ;  A8H998, LEUD_SHEPA ;
DR   A4Y2M3, LEUD_SHEPC ;  B8CM42, LEUD_SHEPW ;  A0L1Q7, LEUD_SHESA ;
DR   A8FQ86, LEUD_SHESH ;  Q0HE68, LEUD_SHESM ;  Q0HZT1, LEUD_SHESR ;
DR   A1REY3, LEUD_SHESW ;  B1KKZ1, LEUD_SHEWM ;  B2U278, LEUD_SHIB3 ;
DR   Q326G4, LEUD_SHIBS ;  Q32K23, LEUD_SHIDS ;  Q0T8C7, LEUD_SHIF8 ;
DR   P59714, LEUD_SHIFL ;  Q3Z5T9, LEUD_SHISS ;  Q5LX07, LEUD_SILPO ;
DR   Q1GDM5, LEUD_SILST ;  A6UDX5, LEUD_SINMW ;  Q2NVW6, LEUD_SODGM ;
DR   Q01Z80, LEUD_SOLUE ;  Q1GR82, LEUD_SPHAL ;  A7X4N4, LEUD_STAA1 ;
DR   A6U3E5, LEUD_STAA2 ;  Q2FF64, LEUD_STAA3 ;  Q2FWK0, LEUD_STAA8 ;
DR   A5IUK6, LEUD_STAA9 ;  Q2YUE9, LEUD_STAAB ;  Q5HEE1, LEUD_STAAC ;
DR   A6QIQ6, LEUD_STAAE ;  P65279, LEUD_STAAM ;  P65280, LEUD_STAAN ;
DR   Q6GF13, LEUD_STAAR ;  Q6G7P8, LEUD_STAAS ;  A8Z4W3, LEUD_STAAT ;
DR   Q8NVI9, LEUD_STAAW ;  Q5HMF6, LEUD_STAEQ ;  Q4L7U3, LEUD_STAHJ ;
DR   Q49Z15, LEUD_STAS1 ;  Q82JR9, LEUD_STRAW ;  O86535, LEUD_STRCO ;
DR   A8AWP6, LEUD_STRGC ;  B1VZ02, LEUD_STRGG ;  Q9AIM2, LEUD_STRGN ;
DR   Q8DTG5, LEUD_STRMU ;  Q97QF9, LEUD_STRPN ;  A4W420, LEUD_STRS2 ;
DR   A3CMJ3, LEUD_STRSV ;  A4VXS3, LEUD_STRSY ;  Q5LZF5, LEUD_STRT1 ;
DR   Q5M407, LEUD_STRT2 ;  Q03KB4, LEUD_STRTD ;  Q4JC10, LEUD_SULAC ;
DR   Q30RK1, LEUD_SULDN ;  C3N1A2, LEUD_SULIA ;  C4KKU5, LEUD_SULIK ;
DR   C3MKR6, LEUD_SULIL ;  C3MUB4, LEUD_SULIM ;  C3NMW1, LEUD_SULIN ;
DR   C3N992, LEUD_SULIY ;  A8Z5R9, LEUD_SULMW ;  Q97VY3, LEUD_SULSO ;
DR   Q974Q9, LEUD_SULTO ;  Q67MJ3, LEUD_SYMTH ;  Q2LWJ1, LEUD_SYNAS ;
DR   P74207, LEUD_SYNY3 ;  C5BL65, LEUD_TERTT ;  Q47SA2, LEUD_THEFY ;
DR   B1YDA5, LEUD_THENV ;  Q72JB2, LEUD_THET2 ;  Q9ZND4, LEUD_THET8 ;
DR   Q8RDK1, LEUD_THETN ;  B5YHE5, LEUD_THEYD ;  Q3SHL2, LEUD_THIDA ;
DR   B8GQD7, LEUD_THISH ;  C4LAV4, LEUD_TOLAT ;  B1H0A5, LEUD_UNCTG ;
DR   C5CSH4, LEUD_VARPS ;  A5CX59, LEUD_VESOH ;  A5F5E3, LEUD_VIBC3 ;
DR   Q9KP80, LEUD_VIBCH ;  C3LR35, LEUD_VIBCM ;  Q5E859, LEUD_VIBF1 ;
DR   B5FGH1, LEUD_VIBFM ;  A7MWB9, LEUD_VIBHB ;  Q87ST0, LEUD_VIBPA ;
DR   B7VIE9, LEUD_VIBSL ;  Q8DED8, LEUD_VIBVU ;  Q7MP80, LEUD_VIBVY ;
DR   Q7M887, LEUD_WOLSU ;  Q8PH04, LEUD_XANAC ;  Q3BPJ7, LEUD_XANC5 ;
DR   Q4UYG4, LEUD_XANC8 ;  Q8P5K9, LEUD_XANCP ;  Q2P764, LEUD_XANOM ;
DR   B2SNH3, LEUD_XANOP ;  Q5H4D0, LEUD_XANOR ;  A7IEJ1, LEUD_XANP2 ;
DR   B2I6I5, LEUD_XYLF2 ;  Q9PAX1, LEUD_XYLFA ;  B0U3M5, LEUD_XYLFM ;
DR   Q87BQ0, LEUD_XYLFT ;  A7FM87, LEUD_YERP3 ;  Q1C1Z3, LEUD_YERPA ;
DR   B2K4C6, LEUD_YERPB ;  Q8ZIH1, LEUD_YERPE ;  A9R145, LEUD_YERPG ;
DR   Q1CMP8, LEUD_YERPN ;  A4TQA5, LEUD_YERPP ;  Q66EM4, LEUD_YERPS ;
DR   B1JKA1, LEUD_YERPY ;  Q5NRC4, LEUD_ZYMMO ;
//
ID   4.2.1.34
DE   (S)-2-methylmalate dehydratase.
AN   Mesaconate hydratase.
CA   (S)-2-methylmalate = 2-methylfumarate + H(2)O.
CC   -!- Also hydrates fumarate to (S)-malate.
//
ID   4.2.1.35
DE   (R)-2-methylmalate dehydratase.
AN   Citraconate hydratase.
CA   (R)-2-methylmalate = 2-methylmaleate + H(2)O.
CF   Iron.
DR   P81291, LEUC_METJA ;  Q58673, LEUD_METJA ;
//
ID   4.2.1.36
DE   Homoaconitate hydratase.
AN   2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase.
AN   Cis-homoaconitase.
AN   HACN.
AN   Homoaconitase.
CA   (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate = (Z)-but-1-ene-1,2,4-
CA   tricarboxylate + H(2)O.
CF   Iron-sulfur.
CC   -!- The enzyme from the hyperthermophilic eubacterium Thermus
CC       thermophilus can catalyze the reaction shown above but cannot
CC       catalyze the previously described reaction, i.e. formation of
CC       homocitrate by hydration of cis-homoaconitate.
CC   -!- The enzyme responsible for the conversion of cis-homoaconitate into
CC       homocitrate in T.thermophilus is unknown at present but the reaction
CC       can be catalyzed in vitro using EC 4.2.1.3 from pig.
PR   PROSITE; PDOC00423;
DR   Q58409, HACA_METJA ;  Q9ZNE0, HACA_THET2 ;  Q58667, HACB_METJA ;
DR   Q9ZND9, HACB_THET2 ;  Q75DX9, LYS4_ASHGO ;  Q4WUL6, LYS4_ASPFU ;
DR   Q58FL6, LYS4_ASPNC ;  Q2U9G3, LYS4_ASPOR ;  Q5A644, LYS4_CANAL ;
DR   Q6FM51, LYS4_CANGA ;  Q2HZ33, LYS4_CANPA ;  Q2GN26, LYS4_CHAGB ;
DR   P0CM03, LYS4_CRYNB ;  P0CM02, LYS4_CRYNJ ;  Q6BM98, LYS4_DEBHA ;
DR   Q92412, LYS4_EMENI ;  Q4HVQ9, LYS4_GIBZE ;  Q6CT61, LYS4_KLULA ;
DR   Q870W1, LYS4_NEUCR ;  Q9UT74, LYS4_SCHPO ;  Q4P521, LYS4_USTMA ;
DR   Q6C791, LYS4_YARLI ;  P49367, LYS4_YEAST ;
//
ID   4.2.1.37
DE   Transferred entry: 3.3.2.4.
//
ID   4.2.1.38
DE   Transferred entry: 4.3.1.20.
//
ID   4.2.1.39
DE   Gluconate dehydratase.
CA   D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H(2)O.
//
ID   4.2.1.40
DE   Glucarate dehydratase.
CA   D-glucarate = 5-dehydro-4-deoxy-D-glucarate + H(2)O.
DR   P42238, GUDH_BACSU ;  P0AES3, GUDH_ECO57 ;  P0AES2, GUDH_ECOLI ;
DR   P42206, GUDH_PSEPU ;  Q9RDE9, GUDH_STRCO ;
//
ID   4.2.1.41
DE   5-dehydro-4-deoxyglucarate dehydratase.
AN   5-keto-4-deoxy-glucarate dehydratase.
AN   D-4-deoxy-5-ketoglucarate hydro-lyase.
CA   5-dehydro-4-deoxy-D-glucarate = 2,5-dioxopentanoate + H(2)O + CO(2).
DR   Q829P9, KDGD1_STRAW;  Q9X9X7, KDGD1_STRCO;  Q82BX4, KDGD2_STRAW;
DR   Q9RDE8, KDGD2_STRCO;  A1TQC1, KDGD_ACIAC ;  Q6FFQ1, KDGD_ACIAD ;
DR   B7GX14, KDGD_ACIB3 ;  B7I9K0, KDGD_ACIB5 ;  B0VL04, KDGD_ACIBS ;
DR   A3M3N7, KDGD_ACIBT ;  B9MJB2, KDGD_ACIET ;  A1W7E4, KDGD_ACISJ ;
DR   B9JLF7, KDGD_AGRRK ;  Q8UB77, KDGD_AGRT5 ;  B9K1N4, KDGD_AGRVS ;
DR   B8H9W6, KDGD_ARTCA ;  A0JQW8, KDGD_ARTS2 ;  C1DJJ0, KDGD_AZOVD ;
DR   Q65NX1, KDGD_BACLD ;  P42235, KDGD_BACSU ;  A9I3W2, KDGD_BORPD ;
DR   Q89HW8, KDGD_BRAJA ;  A5EQF2, KDGD_BRASB ;  A4YNH1, KDGD_BRASO ;
DR   A4QB97, KDGD_CORGB ;  Q8NT57, KDGD_CORGL ;  A9BQU2, KDGD_DELAS ;
DR   B1Y3Z2, KDGD_LEPCP ;  Q11GY5, KDGD_MESSB ;  B1LW44, KDGD_METRJ ;
DR   Q5YTY9, KDGD_NOCFA ;  Q8EMK1, KDGD_OCEIH ;  A1VMN2, KDGD_POLNA ;
DR   Q48E20, KDGD_PSE14 ;  Q1IA73, KDGD_PSEE4 ;  A4XRL4, KDGD_PSEMY ;
DR   A5W516, KDGD_PSEP1 ;  Q3KI36, KDGD_PSEPF ;  B0KPL8, KDGD_PSEPG ;
DR   Q88GW8, KDGD_PSEPK ;  P42233, KDGD_PSEPU ;  B1J9C7, KDGD_PSEPW ;
DR   Q87WJ7, KDGD_PSESM ;  Q4ZNL5, KDGD_PSEU2 ;  B2UIZ4, KDGD_RALPJ ;
DR   Q8XRK5, KDGD_RALSO ;  Q92YS6, KDGD_RHIME ;  C1B5J0, KDGD_RHOOB ;
DR   A3PQ70, KDGD_RHOS1 ;  Q3IW19, KDGD_RHOS4 ;  B9KW45, KDGD_RHOSK ;
DR   Q0SBH9, KDGD_RHOSR ;  A4F6L9, KDGD_SACEN ;  B1W1P9, KDGD_STRGG ;
DR   C5CU29, KDGD_VARPS ;  Q4UY45, KDGD_XANC8 ;  B0RPA3, KDGD_XANCB ;
DR   Q8P5U0, KDGD_XANCP ;  A7IKQ7, KDGD_XANP2 ;
//
ID   4.2.1.42
DE   Galactarate dehydratase.
CA   D-galactarate = 5-dehydro-4-deoxy-D-glucarate + H(2)O.
DR   P42240, GARD_BACSU ;  P39829, GARD_ECOLI ;
//
ID   4.2.1.43
DE   2-dehydro-3-deoxy-L-arabinonate dehydratase.
AN   2-keto-3-deoxy-L-arabinonate dehydratase.
CA   2-dehydro-3-deoxy-L-arabinonate = 2,5-dioxopentanoate + H(2)O.
//
ID   4.2.1.44
DE   Myo-inosose-2 dehydratase.
CA   2,4,6/3,5-pentahydroxycyclohexanone = 3,5/4-trihydroxycyclohexa-1,2-dione
CA   + H(2)O.
CF   Manganese or cobalt.
DR   Q63B72, IOLE1_BACCZ;  Q4V1F4, IOLE2_BACCZ;  A7ZAH7, IOLE_BACA2 ;
DR   C3LHY0, IOLE_BACAC ;  A0REB7, IOLE_BACAH ;  Q6HYJ1, IOLE_BACAN ;
DR   B7JPM4, IOLE_BACC0 ;  C1EVJ4, IOLE_BACC3 ;  Q9KAH0, IOLE_BACHD ;
DR   Q6HIK1, IOLE_BACHK ;  Q65D04, IOLE_BACLD ;  Q5WKY7, IOLE_BACSK ;
DR   P42416, IOLE_BACSU ;  A6M225, IOLE_CLOB8 ;  B2V4K2, IOLE_CLOBA ;
DR   B2TJ88, IOLE_CLOBB ;  Q0TUZ0, IOLE_CLOP1 ;  Q8XP74, IOLE_CLOPE ;
DR   Q898E6, IOLE_CLOTE ;  B2VJP2, IOLE_ERWT9 ;  Q5KYR1, IOLE_GEOKA ;
DR   A4IPB5, IOLE_GEOTN ;  B8F6Y7, IOLE_HAEPS ;  Q0I5A5, IOLE_HAES1 ;
DR   B0URJ9, IOLE_HAES2 ;  B5Y2S3, IOLE_KLEP3 ;  A6THJ4, IOLE_KLEP7 ;
DR   A5YBJ9, IOLE_LACCA ;  B3W8L5, IOLE_LACCB ;  Q88S37, IOLE_LACPL ;
DR   Q601Q3, IOLE_MYCH2 ;  Q4A8D5, IOLE_MYCH7 ;  Q4AAA6, IOLE_MYCHJ ;
DR   B5F3F3, IOLE_SALA4 ;  A9N563, IOLE_SALPB ;  Q8ZK58, IOLE_SALTY ;
DR   A8GKV9, IOLE_SERP5 ;  A1JSK6, IOLE_YERE8 ;
//
ID   4.2.1.45
DE   CDP-glucose 4,6-dehydratase.
CA   CDP-glucose = CDP-4-dehydro-6-deoxy-D-glucose + H(2)O.
CF   NAD.
DR   P26397, RFBG_SALTY ;
//
ID   4.2.1.46
DE   dTDP-glucose 4,6-dehydratase.
CA   dTDP-glucose = dTDP-4-dehydro-6-deoxy-D-glucose + H(2)O.
CF   NAD.
DR   P55462, RFBB_RHISN ;  P37759, RMLB1_ECOLI;  P27830, RMLB2_ECOLI;
DR   Q9ZAE8, RMLB_ACTS5 ;  P55293, RMLB_ECOLX ;  P44914, RMLB_HAEIN ;
DR   A0QSK6, RMLB_MYCS2 ;  O06329, RMLB_MYCTU ;  P37761, RMLB_NEIGO ;
DR   Q9S642, RMLB_NEIMA ;  P55294, RMLB_NEIMB ;  P26391, RMLB_SALTY ;
DR   P37777, RMLB_SHIFL ;  P29782, RMLB_STRGR ;  P95780, RMLB_STRMU ;
DR   B0RVL0, RMLB_XANCB ;  P0C7J0, RMLB_XANCP ;  A6QLW2, TGDS_BOVIN ;
DR   Q54WS6, TGDS_DICDI ;  O95455, TGDS_HUMAN ;  Q5UR12, TGDS_MIMIV ;
DR   Q8VDR7, TGDS_MOUSE ;
//
ID   4.2.1.47
DE   GDP-mannose 4,6-dehydratase.
AN   GDP-D-mannose 4,6-dehydratase.
AN   GDP-D-mannose dehydratase.
AN   Guanosine 5'-diphosphate-D-mannose oxidoreductase.
AN   Guanosine diphosphomannose 4,6-dehydratase.
AN   Guanosine diphosphomannose oxidoreductase.
CA   GDP-mannose = GDP-4-dehydro-6-deoxy-D-mannose + H(2)O.
CF   NAD.
CC   -!- Forms the first step in the biosynthesis of GDP-D-rhamnose and GDP-L-
CC       fucose.
CC   -!- In Aneurinibacillus thermoaerophilus L420-91T, this enzyme acts as a
CC       bifunctional enzyme, catalyzing the above reaction as well as the
CC       reaction catalyzed by EC 1.1.1.281.
DR   Q06952, GM4D1_VIBCH;  Q56598, GM4D2_VIBCH;  P0AC90, GM4D_ECO57 ;
DR   P0AC89, GM4D_ECOL6 ;  P0AC88, GM4D_ECOLI ;  Q51366, GM4D_PSEAE ;
DR   P0AC91, GM4D_SHIFL ;  Q56872, GM4D_YERE8 ;  Q9SNY3, GMD1_ARATH ;
DR   A8Y0L5, GMD1_CAEBR ;  Q18801, GMD1_CAEEL ;  P93031, GMD2_ARATH ;
DR   O45583, GMD2_CAEEL ;  Q8K3X3, GMDS_CRIGR ;  Q1ZXF7, GMDS_DICDI ;
DR   Q9VMW9, GMDS_DROME ;  O60547, GMDS_HUMAN ;  Q8K0C9, GMDS_MOUSE ;
DR   O85713, NOEL_RHIFR ;  P55354, NOEL_RHISN ;
//
ID   4.2.1.48
DE   D-glutamate cyclase.
CA   D-glutamate = 5-oxo-D-proline + H(2)O.
CC   -!- Also acts on various derivatives of D-glutamate.
//
ID   4.2.1.49
DE   Urocanate hydratase.
AN   Imidazolonepropionate hydrolase.
AN   Urocanase.
CA   3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate = urocanate + H(2)O.
CF   NAD.
PR   PROSITE; PDOC00947;
DR   B7GUU5, HUTU_ACIB3 ;  B7I271, HUTU_ACIB5 ;  B2I2C4, HUTU_ACIBC ;
DR   B0VPV2, HUTU_ACIBS ;  B0V9X6, HUTU_ACIBY ;  A5FZC1, HUTU_ACICJ ;
DR   B9JDB9, HUTU_AGRRK ;  Q8U8Z9, HUTU_AGRT5 ;  B9K286, HUTU_AGRVS ;
DR   B6ERX7, HUTU_ALISL ;  C1DJM5, HUTU_AZOVD ;  A7ZAE5, HUTU_BACA2 ;
DR   C3P4M1, HUTU_BACAA ;  C3L983, HUTU_BACAC ;  A0RH38, HUTU_BACAH ;
DR   Q81Y46, HUTU_BACAN ;  B7JI79, HUTU_BACC0 ;  Q733H9, HUTU_BACC1 ;
DR   B7ISJ1, HUTU_BACC2 ;  C1EN92, HUTU_BACC3 ;  B7HCC9, HUTU_BACC4 ;
DR   B7HKJ0, HUTU_BACC7 ;  A7GQZ9, HUTU_BACCN ;  B9IUG9, HUTU_BACCQ ;
DR   Q81AC7, HUTU_BACCR ;  Q637H9, HUTU_BACCZ ;  Q9KBE5, HUTU_BACHD ;
DR   Q6HFF0, HUTU_BACHK ;  Q5WCP7, HUTU_BACSK ;  P25503, HUTU_BACSU ;
DR   A9VPT7, HUTU_BACWK ;  Q6MJM2, HUTU_BDEBA ;  C5C4W6, HUTU_BEUC1 ;
DR   Q89GV4, HUTU_BRAJA ;  A5EQB6, HUTU_BRASB ;  A4YNK8, HUTU_BRASO ;
DR   B2SD94, HUTU_BRUA1 ;  Q2YIL8, HUTU_BRUA2 ;  Q579F0, HUTU_BRUAB ;
DR   A9MCL2, HUTU_BRUC2 ;  C0RM77, HUTU_BRUMB ;  Q8YD12, HUTU_BRUME ;
DR   A5VVJ8, HUTU_BRUO2 ;  A9WVU5, HUTU_BRUSI ;  Q8FVB2, HUTU_BRUSU ;
DR   Q9NAE2, HUTU_CAEEL ;  B8H2R9, HUTU_CAUCN ;  Q9A9M1, HUTU_CAUCR ;
DR   B0SYU4, HUTU_CAUSK ;  Q7P190, HUTU_CHRVO ;  A8AJ16, HUTU_CITK8 ;
DR   Q9RZ02, HUTU_DEIRA ;  Q86AX3, HUTU_DICDI ;  A4W8B4, HUTU_ENT38 ;
DR   P12381, HUTU_ENTAE ;  A7HN21, HUTU_FERNB ;  Q5L084, HUTU_GEOKA ;
DR   C5DA19, HUTU_GEOSW ;  Q2SEP6, HUTU_HAHCH ;  B0R541, HUTU_HALS3 ;
DR   Q9HQD8, HUTU_HALSA ;  A9AW39, HUTU_HERA2 ;  Q96N76, HUTU_HUMAN ;
DR   Q0BZK0, HUTU_HYPNA ;  Q5QV29, HUTU_IDILO ;  B5XZ80, HUTU_KLEP3 ;
DR   A6T6L0, HUTU_KLEP7 ;  Q0AP94, HUTU_MARMM ;  Q11E20, HUTU_MESSB ;
DR   B8II06, HUTU_METNO ;  Q8VC12, HUTU_MOUSE ;  A0QRN3, HUTU_MYCS2 ;
DR   B2A3D8, HUTU_NATTJ ;  A1SQ09, HUTU_NOCSJ ;  A6WYU6, HUTU_OCHA4 ;
DR   B4REE0, HUTU_PHEZH ;  Q7N295, HUTU_PHOLL ;  Q6LQ57, HUTU_PHOPR ;
DR   Q48CE0, HUTU_PSE14 ;  A6VDL7, HUTU_PSEA7 ;  B7V3J3, HUTU_PSEA8 ;
DR   Q02ER6, HUTU_PSEAB ;  Q9HU83, HUTU_PSEAE ;  Q1I3Q8, HUTU_PSEE4 ;
DR   C3K803, HUTU_PSEFS ;  Q3IJC7, HUTU_PSEHT ;  A5WA67, HUTU_PSEP1 ;
DR   B0KM58, HUTU_PSEPG ;  Q88CZ6, HUTU_PSEPK ;  P25080, HUTU_PSEPU ;
DR   B1J2Q5, HUTU_PSEPW ;  Q87UM6, HUTU_PSESM ;  Q9AGU4, HUTU_PSESX ;
DR   Q4ZLW7, HUTU_PSEU2 ;  Q8XW28, HUTU_RALSO ;  Q983H8, HUTU_RHILO ;
DR   Q92V80, HUTU_RHIME ;  Q2RUU0, HUTU_RHORT ;  Q1AYH3, HUTU_RUBXD ;
DR   A4FNF1, HUTU_SACEN ;  B5F068, HUTU_SALA4 ;  A9MJF0, HUTU_SALAR ;
DR   Q57RG7, HUTU_SALCH ;  B5FP57, HUTU_SALDC ;  B5QX61, HUTU_SALEP ;
DR   B5R757, HUTU_SALG2 ;  B4TC44, HUTU_SALHS ;  B4SZJ3, HUTU_SALNS ;
DR   A9MTJ2, HUTU_SALPB ;  C0PWX8, HUTU_SALPC ;  B4TQT5, HUTU_SALSV ;
DR   Q8Z897, HUTU_SALTI ;  B8E3L7, HUTU_SHEB2 ;  A3DAF4, HUTU_SHEB5 ;
DR   A6WHI0, HUTU_SHEB8 ;  A9KV80, HUTU_SHEB9 ;  Q07W36, HUTU_SHEFN ;
DR   B0TM56, HUTU_SHEHH ;  Q8EKJ5, HUTU_SHEON ;  A8HA92, HUTU_SHEPA ;
DR   A4Y1I2, HUTU_SHEPC ;  B8CGY4, HUTU_SHEPW ;  A0KRC6, HUTU_SHESA ;
DR   A8G1S6, HUTU_SHESH ;  Q0HP37, HUTU_SHESM ;  Q0I0K5, HUTU_SHESR ;
DR   A1RQ57, HUTU_SHESW ;  B1KP56, HUTU_SHEWM ;  Q1GSG8, HUTU_SPHAL ;
DR   A5VFA2, HUTU_SPHWW ;  Q5HDM6, HUTU_STAAC ;  Q931G1, HUTU_STAAM ;
DR   P67417, HUTU_STAAN ;  Q6GEA4, HUTU_STAAR ;  Q6G6Y9, HUTU_STAAS ;
DR   P67418, HUTU_STAAW ;  Q49ZQ7, HUTU_STAS1 ;  Q82HL2, HUTU_STRAW ;
DR   Q9KZ75, HUTU_STRCO ;  B1VUR5, HUTU_STRGG ;  B4SP57, HUTU_STRM5 ;
DR   B2FKG1, HUTU_STRMK ;  Q67JH5, HUTU_SYMTH ;  B7IF30, HUTU_THEAB ;
DR   Q9HLI9, HUTU_THEAC ;  A6LP75, HUTU_THEM4 ;  B0KCB9, HUTU_THEP3 ;
DR   Q8RCH9, HUTU_THETN ;  Q978N4, HUTU_THEVO ;  P53385, HUTU_TRIRP ;
DR   A5F1X6, HUTU_VIBC3 ;  Q9KSQ3, HUTU_VIBCH ;  C3LLP9, HUTU_VIBCM ;
DR   A7MVK1, HUTU_VIBHB ;  Q87Q76, HUTU_VIBPA ;  B7VMU2, HUTU_VIBSL ;
DR   Q8DA20, HUTU_VIBVU ;  Q7MK59, HUTU_VIBVY ;  P58987, HUTU_XANAC ;
DR   Q3BV06, HUTU_XANC5 ;  P58988, HUTU_XANCP ;  A1JSW8, HUTU_YERE8 ;
DR   A7FP52, HUTU_YERP3 ;  Q1C0F6, HUTU_YERPA ;  B2K6P6, HUTU_YERPB ;
DR   Q8ZA09, HUTU_YERPE ;  Q1CDD8, HUTU_YERPN ;  A4TS44, HUTU_YERPP ;
DR   Q664B7, HUTU_YERPS ;  B1JH60, HUTU_YERPY ;
//
ID   4.2.1.50
DE   Pyrazolylalanine synthase.
CA   L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + H(2)O.
CF   Pyridoxal 5'-phosphate.
//
ID   4.2.1.51
DE   Prephenate dehydratase.
CA   Prephenate = phenylpyruvate + H(2)O + CO(2).
CC   -!- This enzyme in the enteric bacteria also possesses EC 5.4.99.5
CC       activity and converts chorismate into prephenate.
PR   PROSITE; PDOC00671;
DR   Q9SA96, AROD1_ARATH;  Q9SSE7, AROD2_ARATH;  Q9SGD6, AROD6_ARATH;
DR   O14361, PHA2_SCHPO ;  P32452, PHA2_YEAST ;  Q44104, PHEA_AMYME ;
DR   O67085, PHEA_AQUAE ;  P21203, PHEA_BACSU ;  P57472, PHEA_BUCAI ;
DR   Q8K9F8, PHEA_BUCAP ;  Q89AE5, PHEA_BUCBP ;  P10341, PHEA_CORGL ;
DR   P0A9J9, PHEA_ECO57 ;  P0A9J8, PHEA_ECOLI ;  Q02286, PHEA_ENTAG ;
DR   P43900, PHEA_HAEIN ;  Q9CEU2, PHEA_LACLA ;  P43909, PHEA_LACLM ;
DR   Q58054, PHEA_METJA ;  A0Q994, PHEA_MYCA1 ;  B1MEG8, PHEA_MYCA9 ;
DR   Q7TVJ6, PHEA_MYCBO ;  A1KQH3, PHEA_MYCBP ;  A4T6G3, PHEA_MYCGI ;
DR   B8ZTU2, PHEA_MYCLB ;  Q9CDC4, PHEA_MYCLE ;  B2HMM5, PHEA_MYCMM ;
DR   Q745J2, PHEA_MYCPA ;  A0R643, PHEA_MYCS2 ;  A3Q7Q1, PHEA_MYCSJ ;
DR   A1UNA3, PHEA_MYCSK ;  Q1B1U6, PHEA_MYCSS ;  A5U9G7, PHEA_MYCTA ;
DR   P96240, PHEA_MYCTU ;  A0PX17, PHEA_MYCUA ;  A1TGX7, PHEA_MYCVP ;
DR   Q9ZHY3, PHEA_NEIG1 ;  Q9HZ67, PHEA_PSEAE ;  P27603, PHEA_PSEST ;
DR   P0A9K0, PHEA_SHIFL ;  Q01269, PHEC_PSEAE ;
//
ID   4.2.1.52
DE   Dihydrodipicolinate synthase.
AN   DHDPS.
AN   Dihydrodipicolinate synthetase.
CA   L-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H(2)O.
PR   PROSITE; PDOC00569;
DR   Q9LZX6, DAPA1_ARATH;  Q9KC32, DAPA1_BACHD;  Q97GI9, DAPA1_CLOAB;
DR   Q92R55, DAPA1_RHIME;  O86841, DAPA1_STRCO;  P24846, DAPA1_WHEAT;
DR   Q9FVC8, DAPA2_ARATH;  Q9KA91, DAPA2_BACHD;  Q97D80, DAPA2_CLOAB;
DR   O69782, DAPA2_RHIME;  Q9X9W0, DAPA2_STRCO;  P24847, DAPA2_WHEAT;
DR   B0C142, DAPA_ACAM1 ;  A9NGC2, DAPA_ACHLI ;  Q1INQ6, DAPA_ACIBL ;
DR   A0LV15, DAPA_ACIC1 ;  C1F658, DAPA_ACIC5 ;  A5FZS7, DAPA_ACICJ ;
DR   B9MER6, DAPA_ACIET ;  B7J6C4, DAPA_ACIF2 ;  B5ELM5, DAPA_ACIF5 ;
DR   A1W4S3, DAPA_ACISJ ;  A3N0Q9, DAPA_ACTP2 ;  B3GXP5, DAPA_ACTP7 ;
DR   B0BPI4, DAPA_ACTPJ ;  Q8UGL3, DAPA_AGRT5 ;  Q0VRH4, DAPA_ALCBS ;
DR   Q0A5S1, DAPA_ALHEH ;  B6EJT2, DAPA_ALISL ;  A8MF40, DAPA_ALKOO ;
DR   B8JAN5, DAPA_ANAD2 ;  Q2IGX5, DAPA_ANADE ;  A7H773, DAPA_ANADF ;
DR   B9KI57, DAPA_ANAMF ;  Q5PB64, DAPA_ANAMM ;  B4UHY1, DAPA_ANASK ;
DR   B9MRD1, DAPA_ANATD ;  O67216, DAPA_AQUAE ;  A8ET60, DAPA_ARCB4 ;
DR   O29352, DAPA_ARCFU ;  Q5P838, DAPA_AROAE ;  B6YQ20, DAPA_AZOPC ;
DR   A1K4F8, DAPA_AZOSB ;  A7Z4U8, DAPA_BACA2 ;  Q04796, DAPA_BACSU ;
DR   A6L5G7, DAPA_BACV8 ;  A1US27, DAPA_BARBK ;  Q6G468, DAPA_BARHE ;
DR   Q6G091, DAPA_BARQU ;  A9IRK3, DAPA_BART1 ;  Q6MRM9, DAPA_BDEBA ;
DR   B8DWI2, DAPA_BIFA0 ;  B3DTC8, DAPA_BIFLD ;  Q8G527, DAPA_BIFLO ;
DR   Q7VRT1, DAPA_BLOFL ;  Q492F5, DAPA_BLOPB ;  Q7VXZ8, DAPA_BORPE ;
DR   C0R176, DAPA_BRAHW ;  Q9RH76, DAPA_BRAJA ;  Q57E96, DAPA_BRUAB ;
DR   Q8YG60, DAPA_BRUME ;  A5VPI5, DAPA_BRUO2 ;  Q8G1R0, DAPA_BRUSU ;
DR   B8D8P8, DAPA_BUCA5 ;  P57197, DAPA_BUCAI ;  Q8KA24, DAPA_BUCAP ;
DR   B8D702, DAPA_BUCAT ;  Q89AY0, DAPA_BUCBP ;  Q058B1, DAPA_BUCCC ;
DR   A4XJU0, DAPA_CALS8 ;  A7ZDQ5, DAPA_CAMC1 ;  A7GYB0, DAPA_CAMC5 ;
DR   A0RP26, DAPA_CAMFF ;  A7I0Y0, DAPA_CAMHC ;  A8FLL9, DAPA_CAMJ8 ;
DR   A7H443, DAPA_CAMJD ;  Q9PPB4, DAPA_CAMJE ;  A1VZF4, DAPA_CAMJJ ;
DR   Q5HUY6, DAPA_CAMJR ;  B9KFX0, DAPA_CAMLR ;  Q9A900, DAPA_CAUCR ;
DR   B3PC19, DAPA_CELJU ;  A9WE23, DAPA_CHLAA ;  Q5L5G7, DAPA_CHLAB ;
DR   Q3APU0, DAPA_CHLCH ;  Q822H0, DAPA_CHLCV ;  Q255G0, DAPA_CHLFF ;
DR   B3EH29, DAPA_CHLL2 ;  Q9PK33, DAPA_CHLMU ;  B3QM33, DAPA_CHLP8 ;
DR   B3EMS4, DAPA_CHLPB ;  A1BE04, DAPA_CHLPD ;  Q9Z6K9, DAPA_CHLPN ;
DR   B3QUT2, DAPA_CHLT3 ;  Q3KLZ5, DAPA_CHLTA ;  Q8KC06, DAPA_CHLTE ;
DR   O84366, DAPA_CHLTR ;  Q1QTP6, DAPA_CHRSD ;  A0PZM3, DAPA_CLONN ;
DR   Q0TP55, DAPA_CLOP1 ;  Q8XJ56, DAPA_CLOPE ;  A9KHY6, DAPA_CLOPH ;
DR   Q0SRS5, DAPA_CLOPS ;  Q891S3, DAPA_CLOTE ;  A3DE17, DAPA_CLOTH ;
DR   Q39535, DAPA_COILA ;  C3PH04, DAPA_CORA7 ;  Q6NGP4, DAPA_CORDI ;
DR   Q8RQM8, DAPA_COREF ;  P19808, DAPA_CORGL ;  Q4JV64, DAPA_CORJK ;
DR   B1VDC4, DAPA_CORU7 ;  A9KFS0, DAPA_COXBN ;  A9NDT3, DAPA_COXBR ;
DR   Q83CA6, DAPA_COXBU ;  B8HYL7, DAPA_CYAP4 ;  Q11VI2, DAPA_CYTH3 ;
DR   Q47HS9, DAPA_DECAR ;  Q3Z7V3, DAPA_DEHE1 ;  A5FQT5, DAPA_DEHSB ;
DR   Q3ZXV3, DAPA_DEHSC ;  C6BSH4, DAPA_DESAD ;  B1I383, DAPA_DESAP ;
DR   Q310Q2, DAPA_DESDG ;  Q6AR63, DAPA_DESPS ;  A4J5V5, DAPA_DESRM ;
DR   Q72AX2, DAPA_DESVH ;  B8DKU0, DAPA_DESVM ;  A1VCZ9, DAPA_DESVV ;
DR   A5EXM4, DAPA_DICNV ;  A8LKQ5, DAPA_DINSH ;  A7ZPS4, DAPA_ECO24 ;
DR   B7LCL6, DAPA_ECO55 ;  P63944, DAPA_ECO57 ;  B5Z015, DAPA_ECO5E ;
DR   B7NQL6, DAPA_ECO7I ;  B7MYB7, DAPA_ECO81 ;  B7M7I1, DAPA_ECO8A ;
DR   A8A2X1, DAPA_ECOHS ;  P63943, DAPA_ECOL6 ;  B1IWI1, DAPA_ECOLC ;
DR   P0A6L2, DAPA_ECOLI ;  B6I548, DAPA_ECOSE ;  B1LNC8, DAPA_ECOSM ;
DR   C5B7A2, DAPA_EDWI9 ;  Q3YSK1, DAPA_EHRCJ ;  Q2GG09, DAPA_EHRCR ;
DR   Q836D1, DAPA_ENTFA ;  A7MP70, DAPA_ENTS8 ;  B2VE56, DAPA_ERWT9 ;
DR   Q2N9J7, DAPA_ERYLH ;  B7LKG3, DAPA_ESCF3 ;  B1YJ39, DAPA_EXIS2 ;
DR   C4L2D2, DAPA_EXISA ;  A7HJ56, DAPA_FERNB ;  A5FE82, DAPA_FLAJ1 ;
DR   A6H0M8, DAPA_FLAPJ ;  B0TWJ4, DAPA_FRAP2 ;  A0Q8L5, DAPA_FRATN ;
DR   B5EGX4, DAPA_GEOBB ;  B3E936, DAPA_GEOLS ;  Q39Z67, DAPA_GEOMG ;
DR   B9M380, DAPA_GEOSF ;  Q74GT6, DAPA_GEOSL ;  C6E9Q9, DAPA_GEOSM ;
DR   A5GD89, DAPA_GEOUR ;  A9HIW2, DAPA_GLUDA ;  Q5FUW9, DAPA_GLUOX ;
DR   A0LZ30, DAPA_GRAFK ;  Q7VM87, DAPA_HAEDU ;  Q4QNT3, DAPA_HAEI8 ;
DR   A5UAN5, DAPA_HAEIE ;  A5UG62, DAPA_HAEIG ;  P43797, DAPA_HAEIN ;
DR   Q0I260, DAPA_HAES1 ;  B0UVZ8, DAPA_HAES2 ;  A1WZ50, DAPA_HALHL ;
DR   Q5V5D4, DAPA_HALMA ;  B0R3D6, DAPA_HALS3 ;  Q9HS19, DAPA_HALSA ;
DR   Q17WU7, DAPA_HELAH ;  Q7VFP9, DAPA_HELHP ;  B0THT2, DAPA_HELMI ;
DR   B6JL09, DAPA_HELP2 ;  B5Z6I0, DAPA_HELPG ;  Q1CU72, DAPA_HELPH ;
DR   Q9ZM13, DAPA_HELPJ ;  B2USR7, DAPA_HELPS ;  O25657, DAPA_HELPY ;
DR   A4G724, DAPA_HERAR ;  B4U7D7, DAPA_HYDS0 ;  Q0BYG4, DAPA_HYPNA ;
DR   Q5QU03, DAPA_IDILO ;  Q28WG2, DAPA_JANSC ;  A6W828, DAPA_KINRD ;
DR   A6TCA1, DAPA_KLEP7 ;  C5CHX9, DAPA_KOSOT ;  Q5FKQ9, DAPA_LACAC ;
DR   Q03CW3, DAPA_LACC3 ;  B3W7E5, DAPA_LACCB ;  B2GC11, DAPA_LACF3 ;
DR   A8YUT3, DAPA_LACH4 ;  Q9CF61, DAPA_LACLA ;  A2RJL6, DAPA_LACLM ;
DR   Q02XU7, DAPA_LACLS ;  A5VJ58, DAPA_LACRD ;  B2G6M9, DAPA_LACRJ ;
DR   Q1WU86, DAPA_LACS1 ;  C1DD55, DAPA_LARHH ;  Q1MPX7, DAPA_LAWIP ;
DR   A5IEB3, DAPA_LEGPC ;  Q5ZT51, DAPA_LEGPH ;  Q5WUD4, DAPA_LEGPL ;
DR   B0SCT0, DAPA_LEPBA ;  Q04U80, DAPA_LEPBJ ;  Q053P3, DAPA_LEPBL ;
DR   B0SL58, DAPA_LEPBP ;  B1Y7F0, DAPA_LEPCP ;  Q72U22, DAPA_LEPIC ;
DR   Q8F132, DAPA_LEPIN ;  B1MZM8, DAPA_LEUCK ;  Q03YE2, DAPA_LEUMM ;
DR   Q92BS0, DAPA_LISIN ;  C1L2Z1, DAPA_LISMC ;  Q71ZN5, DAPA_LISMF ;
DR   B8DE74, DAPA_LISMH ;  Q8Y766, DAPA_LISMO ;  A0AIN8, DAPA_LISW6 ;
DR   B9EBZ6, DAPA_MACCJ ;  A0LDB5, DAPA_MAGSM ;  P26259, DAPA_MAIZE ;
DR   A1U1A6, DAPA_MARAV ;  Q11JT7, DAPA_MESSB ;  A6UVG7, DAPA_META3 ;
DR   Q8THP1, DAPA_METAC ;  Q46DC4, DAPA_METBF ;  Q12ZG2, DAPA_METBU ;
DR   Q60B13, DAPA_METCA ;  Q2FNR0, DAPA_METHJ ;  Q57695, DAPA_METJA ;
DR   Q8TUZ4, DAPA_METKA ;  A2SQU8, DAPA_METLZ ;  A4FYQ3, DAPA_METM5 ;
DR   A9A656, DAPA_METM6 ;  A6VJM9, DAPA_METM7 ;  Q8PXL7, DAPA_METMA ;
DR   A3CVI7, DAPA_METMJ ;  Q6LZP8, DAPA_METMP ;  B8GKG7, DAPA_METPE ;
DR   A2SIX7, DAPA_METPP ;  B1LTD9, DAPA_METRJ ;  A5ULF8, DAPA_METS3 ;
DR   Q2NHW2, DAPA_METST ;  O26892, DAPA_METTH ;  A0B7E1, DAPA_METTP ;
DR   A6US71, DAPA_METVS ;  B0JL91, DAPA_MICAN ;  Q2RJK7, DAPA_MOOTA ;
DR   P63946, DAPA_MYCBO ;  A1KM94, DAPA_MYCBP ;  C1AFL5, DAPA_MYCBT ;
DR   A4TCJ3, DAPA_MYCGI ;  B8ZRR3, DAPA_MYCLB ;  Q9CBW4, DAPA_MYCLE ;
DR   Q73VZ7, DAPA_MYCPA ;  A5U6A6, DAPA_MYCTA ;  P63945, DAPA_MYCTU ;
DR   Q3ISQ0, DAPA_NATPD ;  B2A3B2, DAPA_NATTJ ;  Q5F849, DAPA_NEIG1 ;
DR   A9M4C8, DAPA_NEIM0 ;  Q9JUU9, DAPA_NEIMA ;  Q9JZR4, DAPA_NEIMB ;
DR   A1KTJ9, DAPA_NEIMF ;  Q0AI27, DAPA_NITEC ;  Q82SD7, DAPA_NITEU ;
DR   Q1QL43, DAPA_NITHX ;  Q2Y8S8, DAPA_NITMU ;  Q3J869, DAPA_NITOC ;
DR   A6Q2V4, DAPA_NITSB ;  B2IT87, DAPA_NOSP7 ;  Q8YQY1, DAPA_NOSS1 ;
DR   Q2G8D6, DAPA_NOVAD ;  Q8EQJ1, DAPA_OCEIH ;  Q04FS1, DAPA_OENOB ;
DR   B6JGA4, DAPA_OLICO ;  A6LA57, DAPA_PARD8 ;  A7HX36, DAPA_PARL1 ;
DR   Q6MDD9, DAPA_PARUW ;  Q9CLZ7, DAPA_PASMU ;  Q03HT2, DAPA_PEDPA ;
DR   Q3A1U7, DAPA_PELCD ;  Q3B2G4, DAPA_PELLD ;  B4SE03, DAPA_PELPB ;
DR   A1ATI8, DAPA_PELPD ;  A5D2Q5, DAPA_PELTS ;  Q4FLS1, DAPA_PELUB ;
DR   C0QT41, DAPA_PERMH ;  B4RCW4, DAPA_PHEZH ;  Q6LN85, DAPA_PHOPR ;
DR   A4SX51, DAPA_POLSQ ;  B2RMB9, DAPA_PORG3 ;  B4S5J5, DAPA_PROA2 ;
DR   Q6AA18, DAPA_PROAC ;  A3PFE1, DAPA_PROM0 ;  A8G7F8, DAPA_PROM2 ;
DR   A2C5R9, DAPA_PROM3 ;  A9BD97, DAPA_PROM4 ;  A2BZ39, DAPA_PROM5 ;
DR   Q317Y9, DAPA_PROM9 ;  P49423, DAPA_PROMA ;  Q7V990, DAPA_PROMM ;
DR   Q7UZK9, DAPA_PROMP ;  A2BTN4, DAPA_PROMS ;  Q46ID7, DAPA_PROMT ;
DR   A4SG05, DAPA_PROVI ;  Q48LD5, DAPA_PSE14 ;  Q15SZ4, DAPA_PSEA6 ;
DR   Q9I4W3, DAPA_PSEAE ;  A4XSW1, DAPA_PSEMY ;  B1JDB7, DAPA_PSEPW ;
DR   Q4ZW75, DAPA_PSEU2 ;  A4VN86, DAPA_PSEU5 ;  Q4FVD6, DAPA_PSYA2 ;
DR   A1SVX2, DAPA_PSYIN ;  A5WHC3, DAPA_PSYWF ;  Q9UZ94, DAPA_PYRAB ;
DR   Q8ZU75, DAPA_PYRAE ;  A4WJK5, DAPA_PYRAR ;  Q8U319, DAPA_PYRFU ;
DR   O58577, DAPA_PYRHO ;  A1RRA5, DAPA_PYRIL ;  Q5JGK8, DAPA_PYRKO ;
DR   Q8Y099, DAPA_RALSO ;  P58207, DAPA_RHILO ;  B6IN13, DAPA_RHOCS ;
DR   Q21WN2, DAPA_RHOFD ;  Q07M65, DAPA_RHOP5 ;  A4WNS1, DAPA_RHOS5 ;
DR   C3PNF5, DAPA_RICAE ;  A8GNF1, DAPA_RICAH ;  A8GWS1, DAPA_RICB8 ;
DR   Q1RIJ3, DAPA_RICBR ;  A8EYZ4, DAPA_RICCK ;  Q92I25, DAPA_RICCN ;
DR   Q4ULR2, DAPA_RICFE ;  A8F1K3, DAPA_RICM5 ;  Q9AKQ3, DAPA_RICMO ;
DR   O05969, DAPA_RICPR ;  C4K288, DAPA_RICPU ;  Q9AKJ9, DAPA_RICRI ;
DR   B0BXJ1, DAPA_RICRO ;  A8GS25, DAPA_RICRS ;  Q9AKE4, DAPA_RICTY ;
DR   Q16BK4, DAPA_ROSDO ;  A1AVV3, DAPA_RUTMC ;  Q21HE7, DAPA_SACD2 ;
DR   A9MHQ2, DAPA_SALAR ;  Q5PLS1, DAPA_SALPA ;  B5BB16, DAPA_SALPK ;
DR   Q2S3M1, DAPA_SALRD ;  B4TR62, DAPA_SALSV ;  Q8Z4R8, DAPA_SALTI ;
DR   Q8ZN71, DAPA_SALTY ;  B8E724, DAPA_SHEB2 ;  A3D5N2, DAPA_SHEB5 ;
DR   A6WPI6, DAPA_SHEB8 ;  A9L573, DAPA_SHEB9 ;  Q12NF7, DAPA_SHEDO ;
DR   Q082V3, DAPA_SHEFN ;  Q8EFT7, DAPA_SHEON ;  A8H415, DAPA_SHEPA ;
DR   A4Y644, DAPA_SHEPC ;  B8CMS5, DAPA_SHEPW ;  A0KVS0, DAPA_SHESA ;
DR   Q0HHQ6, DAPA_SHESM ;  Q0HU08, DAPA_SHESR ;  A1RKF2, DAPA_SHESW ;
DR   B2TXQ4, DAPA_SHIB3 ;  Q31Y13, DAPA_SHIBS ;  Q32D87, DAPA_SHIDS ;
DR   Q0T239, DAPA_SHIF8 ;  P0A6L3, DAPA_SHIFL ;  Q3YZ74, DAPA_SHISS ;
DR   Q5LMK7, DAPA_SILPO ;  Q2NS74, DAPA_SODGM ;  A9FHA5, DAPA_SORC5 ;
DR   Q42800, DAPA_SOYBN ;  Q1GSC8, DAPA_SPHAL ;  A5V3L9, DAPA_SPHWW ;
DR   A7X271, DAPA_STAA1 ;  A6U1L6, DAPA_STAA2 ;  Q2FH43, DAPA_STAA3 ;
DR   Q9EZ12, DAPA_STAA8 ;  A5ISS7, DAPA_STAA9 ;  Q2YXX4, DAPA_STAAB ;
DR   Q5HG25, DAPA_STAAC ;  A6QGU6, DAPA_STAAE ;  P63947, DAPA_STAAM ;
DR   P63948, DAPA_STAAN ;  Q6GH13, DAPA_STAAR ;  Q6G9G6, DAPA_STAAS ;
DR   A8Z3X3, DAPA_STAAT ;  Q8NWS5, DAPA_STAAW ;  B9DP23, DAPA_STACT ;
DR   Q5HPE7, DAPA_STAEQ ;  Q8CP96, DAPA_STAES ;  Q4L6A0, DAPA_STAHJ ;
DR   Q49XJ7, DAPA_STAS1 ;  A8AXI2, DAPA_STRGC ;  B4SRX7, DAPA_STRM5 ;
DR   B2FL61, DAPA_STRMK ;  Q8DUE5, DAPA_STRMU ;  Q04KR9, DAPA_STRP2 ;
DR   B5E4D5, DAPA_STRP4 ;  C1C6Z0, DAPA_STRP7 ;  B1IBH4, DAPA_STRPI ;
DR   B8ZPG7, DAPA_STRPJ ;  Q97R25, DAPA_STRPN ;  B2IPH2, DAPA_STRPS ;
DR   Q8DPZ9, DAPA_STRR6 ;  A4W0I7, DAPA_STRS2 ;  A3CN43, DAPA_STRSV ;
DR   A4VU96, DAPA_STRSY ;  Q03K16, DAPA_STRTD ;  B9DS79, DAPA_STRU0 ;
DR   C1CE08, DAPA_STRZJ ;  C1CK93, DAPA_STRZP ;  C1CRD6, DAPA_STRZT ;
DR   Q30R77, DAPA_SULDN ;  A8Z624, DAPA_SULMW ;  A6Q8F8, DAPA_SULNB ;
DR   B2V6F1, DAPA_SULSY ;  Q67P59, DAPA_SYMTH ;  Q2LTA1, DAPA_SYNAS ;
DR   Q31M42, DAPA_SYNE7 ;  A0LEA7, DAPA_SYNFM ;  Q2JWL7, DAPA_SYNJA ;
DR   Q2JQ67, DAPA_SYNJB ;  Q5MZT3, DAPA_SYNP6 ;  A5GHT4, DAPA_SYNPW ;
DR   Q7UA33, DAPA_SYNPX ;  A5GQ13, DAPA_SYNR3 ;  Q0IE16, DAPA_SYNS3 ;
DR   Q3B0T8, DAPA_SYNS9 ;  Q3ANI5, DAPA_SYNSC ;  Q55513, DAPA_SYNY3 ;
DR   C5BQD1, DAPA_TERTT ;  B7IF13, DAPA_THEAB ;  Q9HJ17, DAPA_THEAC ;
DR   Q8DJK4, DAPA_THEEB ;  A6LP58, DAPA_THEM4 ;  Q9X1K9, DAPA_THEMA ;
DR   B9K865, DAPA_THENN ;  B1YB29, DAPA_THENV ;  B6YU51, DAPA_THEON ;
DR   A5IM62, DAPA_THEP1 ;  B0KAL7, DAPA_THEP3 ;  A1S0T1, DAPA_THEPD ;
DR   B0K4I3, DAPA_THEPX ;  B9KY71, DAPA_THERP ;  B1LBR1, DAPA_THESQ ;
DR   Q72K27, DAPA_THET2 ;  Q5SJQ1, DAPA_THET8 ;  Q8RBI5, DAPA_THETN ;
DR   B5YKK4, DAPA_THEYD ;  Q3SJU8, DAPA_THIDA ;  B8GN57, DAPA_THISH ;
DR   Q42948, DAPA_TOBAC ;  B1GYN1, DAPA_UNCTG ;  A5F699, DAPA_VIBC3 ;
DR   Q9KQ47, DAPA_VIBCH ;  C3LPG2, DAPA_VIBCM ;  Q5E3I3, DAPA_VIBF1 ;
DR   B5FGX4, DAPA_VIBFM ;  Q8DBB0, DAPA_VIBVU ;  Q7MIL2, DAPA_VIBVY ;
DR   Q8D2M3, DAPA_WIGBR ;  Q73H02, DAPA_WOLPM ;  B3CM06, DAPA_WOLPP ;
DR   Q7M7L6, DAPA_WOLSU ;  Q8PLN5, DAPA_XANAC ;  Q8P9V6, DAPA_XANCP ;
DR   Q9PER5, DAPA_XYLFA ;  Q87AT3, DAPA_XYLFT ;  A1JL07, DAPA_YERE8 ;
DR   A7FG49, DAPA_YERP3 ;  Q8ZCD0, DAPA_YERPE ;  A4TMN2, DAPA_YERPP ;
DR   Q668F7, DAPA_YERPS ;  Q5NPL6, DAPA_ZYMMO ;
//
ID   4.2.1.53
DE   Oleate hydratase.
CA   (R)-10-hydroxystearate = oleate + H(2)O.
CC   -!- Acts on a number of 10-hydroxy acids.
//
ID   4.2.1.54
DE   Lactoyl-CoA dehydratase.
CA   Lactoyl-CoA = acryloyl-CoA + H(2)O.
//
ID   4.2.1.55
DE   3-hydroxybutyryl-CoA dehydratase.
AN   Crotonase.
CA   (3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H(2)O.
CC   -!- Also acts on crotonoyl thioesters of pantetheine and acyl-carrier
CC       protein.
PR   PROSITE; PDOC00150;
DR   P52046, CRT_CLOAB  ;  P45361, CRT_CLODI  ;  P81357, CRT_CLOPA  ;
//
ID   4.2.1.56
DE   Itaconyl-CoA hydratase.
CA   Citramalyl-CoA = itaconyl-CoA + H(2)O.
//
ID   4.2.1.57
DE   Isohexenylglutaconyl-CoA hydratase.
CA   3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = 3-(4-methylpent-3-
CA   en-1-yl)pent-2-enedioyl-CoA + H(2)O.
CC   -!- Also acts on dimethylacryloyl-CoA and farnesoyl-CoA.
//
ID   4.2.1.58
DE   Crotonoyl-[acyl-carrier-protein] hydratase.
AN   (3R)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase.
AN   3-hydroxybutyryl acyl carrier protein dehydratase.
AN   Beta-hydroxybutyryl acyl carrier protein (ACP) dehydrase.
AN   Beta-hydroxybutyryl acyl carrier protein dehydrase.
AN   Crotonyl acyl carrier protein hydratase.
AN   Enoyl acyl carrier protein hydrase.
CA   (3R)-3-hydroxybutanoyl-[acyl-carrier-protein] = but-2-enoyl-[acyl-
CA   carrier-protein] + H(2)O.
CC   -!- Specific for short-chain length 3-hydroxyacyl-[acyl-carrier-protein]
CC       derivatives C(4) to C(8).
//
ID   4.2.1.59
DE   3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase.
AN   (3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] hydro-lyase.
AN   Beta-hydroxyoctanoyl thioester dehydratase.
AN   Beta-hydroxyoctanoyl-ACP-dehydrase.
AN   Beta-hydroxyoctanoyl-acyl carrier protein dehydrase.
AN   D-3-hydroxyoctanoyl-[acyl carrier protein] dehydratase.
AN   D-3-hydroxyoctanoyl-acyl carrier protein dehydratase.
CA   (3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] = oct-2-enoyl-[acyl-
CA   carrier-protein] + H(2)O.
CC   -!- Specific for 3-hydroxyacyl-[acyl-carrier-protein] derivatives C(6) to
CC       C(12).
//
ID   4.2.1.60
DE   3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase.
AN   3-hydroxydecanoyl-acyl carrier protein dehydrase.
AN   3-hydroxydecanoyl-acyl carrier protein dehydratase.
AN   Beta-hydroxyacyl-ACP dehydrase.
AN   Beta-hydroxyacyl-acyl carrier protein dehydratase.
AN   Beta-hydroxydecanoate dehydrase.
AN   Beta-hydroxydecanoyl thioester dehydrase.
AN   Beta-hydroxydecanoyl thiol ester dehydrase.
AN   D-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase.
AN   HDDase.
CA   (1) (3R)-3-hydroxydecanoyl-[acyl-carrier-protein] = trans-dec-2-enoyl-
CA   [acyl-carrier-protein] + H(2)O.
CA   (2) (3R)-3-hydroxydecanoyl-[acyl-carrier-protein] = cis-dec-3-enoyl-
CA   [acyl-carrier-protein] + H(2)O.
CC   -!- Specific for C(10) chain length.
DR   A3N3I3, FABA_ACTP2 ;  B3H2V8, FABA_ACTP7 ;  B0BTG8, FABA_ACTPJ ;
DR   A6VPA5, FABA_ACTSZ ;  B9JGS3, FABA_AGRRK ;  Q7D235, FABA_AGRT5 ;
DR   B9JYL4, FABA_AGRVS ;  Q0VRB5, FABA_ALCBS ;  Q0A8W4, FABA_ALHEH ;
DR   B6ELS3, FABA_ALISL ;  C1DLY7, FABA_AZOVD ;  Q1LT61, FABA_BAUCH ;
DR   Q7U352, FABA_BLOFL ;  Q492P4, FABA_BLOPB ;  Q89WC3, FABA_BRAJA ;
DR   A5E877, FABA_BRASB ;  A4YJF9, FABA_BRASO ;  B2S9G5, FABA_BRUA1 ;
DR   Q2YQQ8, FABA_BRUA2 ;  Q57A93, FABA_BRUAB ;  A9MA02, FABA_BRUC2 ;
DR   C0RG54, FABA_BRUMB ;  P64103, FABA_BRUME ;  A5VTB9, FABA_BRUO2 ;
DR   B0CK19, FABA_BRUSI ;  P64104, FABA_BRUSU ;  B8GVZ8, FABA_CAUCN ;
DR   Q9A246, FABA_CAUCR ;  B0T7B6, FABA_CAUSK ;  B3PK88, FABA_CELJU ;
DR   Q1R0D9, FABA_CHRSD ;  A8AIC5, FABA_CITK8 ;  Q47Z14, FABA_COLP3 ;
DR   A7ZK57, FABA_ECO24 ;  B7UN33, FABA_ECO27 ;  B7MHQ6, FABA_ECO45 ;
DR   B7LE54, FABA_ECO55 ;  P0A6Q4, FABA_ECO57 ;  B5YT84, FABA_ECO5E ;
DR   B7NM20, FABA_ECO7I ;  B7MS65, FABA_ECO81 ;  B7M883, FABA_ECO8A ;
DR   C4ZQ80, FABA_ECOBW ;  B1X8Q8, FABA_ECODH ;  A7ZYQ6, FABA_ECOHS ;
DR   Q0TJA7, FABA_ECOL5 ;  Q8FJ83, FABA_ECOL6 ;  B1IVX8, FABA_ECOLC ;
DR   P0A6Q3, FABA_ECOLI ;  B7N3B6, FABA_ECOLU ;  B6I928, FABA_ECOSE ;
DR   B1LJQ9, FABA_ECOSM ;  Q1RDR0, FABA_ECOUT ;  C5BD83, FABA_EDWI9 ;
DR   A4W8W6, FABA_ENT38 ;  A7MEX0, FABA_ENTS8 ;  Q6D6D7, FABA_ERWCT ;
DR   B2VDE7, FABA_ERWT9 ;  B7LNW4, FABA_ESCF3 ;  Q7U343, FABA_HAEDU ;
DR   Q4QKK1, FABA_HAEI8 ;  A5UEY7, FABA_HAEIG ;  P45159, FABA_HAEIN ;
DR   B8F8M2, FABA_HAEPS ;  Q0I3F9, FABA_HAES1 ;  Q2S8H5, FABA_HAHCH ;
DR   A1WT00, FABA_HALHL ;  C4K8W9, FABA_HAMD5 ;  Q0BWN5, FABA_HYPNA ;
DR   Q5QYY0, FABA_IDILO ;  B5XY51, FABA_KLEP3 ;  A6T748, FABA_KLEP7 ;
DR   Q65TA9, FABA_MANSM ;  Q0AK52, FABA_MARMM ;  A6W357, FABA_MARMS ;
DR   Q11BB9, FABA_MESSB ;  Q603C9, FABA_METCA ;  Q1H026, FABA_METFK ;
DR   Q1QS54, FABA_NITHX ;  Q3J9C3, FABA_NITOC ;  Q3SWN9, FABA_NITWN ;
DR   A6WWV7, FABA_OCHA4 ;  B6JCR2, FABA_OLICO ;  Q9CNE8, FABA_PASMU ;
DR   C6DKY2, FABA_PECCP ;  Q7MB46, FABA_PHOLL ;  Q6LR96, FABA_PHOPR ;
DR   B4EVD3, FABA_PROMH ;  Q48K61, FABA_PSE14 ;  Q15UB1, FABA_PSEA6 ;
DR   A6V7I3, FABA_PSEA7 ;  B7UVB1, FABA_PSEA8 ;  Q02K95, FABA_PSEAB ;
DR   O33877, FABA_PSEAE ;  Q1I7M6, FABA_PSEE4 ;  Q4KFX0, FABA_PSEF5 ;
DR   C3K743, FABA_PSEFS ;  Q3IGG9, FABA_PSEHT ;  A4XV59, FABA_PSEMY ;
DR   A5W140, FABA_PSEP1 ;  Q3K8F5, FABA_PSEPF ;  B0KNV6, FABA_PSEPG ;
DR   Q88FC4, FABA_PSEPK ;  B1JAU1, FABA_PSEPW ;  Q883Y6, FABA_PSESM ;
DR   Q4ZUV9, FABA_PSEU2 ;  A4VKR6, FABA_PSEU5 ;  Q98BH8, FABA_RHILO ;
DR   Q92SV8, FABA_RHIME ;  C3MC75, FABA_RHISN ;  Q2J2I6, FABA_RHOP2 ;
DR   Q07V18, FABA_RHOP5 ;  P61450, FABA_RHOPA ;  Q21CG2, FABA_RHOPB ;
DR   Q13EM9, FABA_RHOPS ;  B3QAA3, FABA_RHOPT ;  Q21M18, FABA_SACD2 ;
DR   B5F1V1, FABA_SALA4 ;  A9MHT5, FABA_SALAR ;  Q57QT6, FABA_SALCH ;
DR   B5FQZ7, FABA_SALDC ;  B5QZF7, FABA_SALEP ;  B5R6C0, FABA_SALG2 ;
DR   B4TDZ4, FABA_SALHS ;  B4T1Z7, FABA_SALNS ;  Q5PGD2, FABA_SALPA ;
DR   A9N6X4, FABA_SALPB ;  C0Q8D8, FABA_SALPC ;  B5BBL3, FABA_SALPK ;
DR   B4TSI0, FABA_SALSV ;  P64106, FABA_SALTI ;  P64105, FABA_SALTY ;
DR   A8GCL5, FABA_SERP5 ;  A1S606, FABA_SHEAM ;  B8E711, FABA_SHEB2 ;
DR   A3D5P5, FABA_SHEB5 ;  A6WPK1, FABA_SHEB8 ;  A9L586, FABA_SHEB9 ;
DR   Q12LD1, FABA_SHEDO ;  Q07ZR8, FABA_SHEFN ;  B0TIX2, FABA_SHEHH ;
DR   A3QDY5, FABA_SHELP ;  Q8EFV9, FABA_SHEON ;  A8H3Y6, FABA_SHEPA ;
DR   A4Y5X9, FABA_SHEPC ;  B8CPF2, FABA_SHEPW ;  A0KVM1, FABA_SHESA ;
DR   A8FW54, FABA_SHESH ;  Q0HJZ4, FABA_SHESM ;  Q0HW95, FABA_SHESR ;
DR   A1RKL7, FABA_SHESW ;  B1KDN5, FABA_SHEWM ;  B2TTU1, FABA_SHIB3 ;
DR   Q31YL7, FABA_SHIBS ;  Q32HV2, FABA_SHIDS ;  P0A6Q5, FABA_SHIFL ;
DR   Q3Z3G7, FABA_SHISS ;  A6UF38, FABA_SINMW ;  Q2NU74, FABA_SODGM ;
DR   B4SIF4, FABA_STRM5 ;  B2FLR1, FABA_STRMK ;  C5BQA1, FABA_TERTT ;
DR   Q31E87, FABA_THICR ;  A5F850, FABA_VIBC3 ;  Q9KS00, FABA_VIBCH ;
DR   C3LMG6, FABA_VIBCM ;  Q5E5A9, FABA_VIBF1 ;  B5FE24, FABA_VIBFM ;
DR   A7N0M3, FABA_VIBHB ;  Q87PC5, FABA_VIBPA ;  Q8D9H3, FABA_VIBVU ;
DR   Q7M7J5, FABA_VIBVY ;  Q8D2Q4, FABA_WIGBR ;  Q8PGJ2, FABA_XANAC ;
DR   Q3BP41, FABA_XANC5 ;  Q4UQI1, FABA_XANC8 ;  B0RVP4, FABA_XANCB ;
DR   Q8PCW9, FABA_XANCP ;  Q2P7N0, FABA_XANOM ;  Q5H4V4, FABA_XANOR ;
DR   B2I7H0, FABA_XYLF2 ;  Q9PFT5, FABA_XYLFA ;  B0U452, FABA_XYLFM ;
DR   Q87B86, FABA_XYLFT ;  A1JMS5, FABA_YERE8 ;  A7FJT3, FABA_YERP3 ;
DR   Q1CA31, FABA_YERPA ;  Q8ZG80, FABA_YERPE ;  A9R7H1, FABA_YERPG ;
DR   Q1CGK4, FABA_YERPN ;  Q66CF3, FABA_YERPS ;
//
ID   4.2.1.61
DE   3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase.
AN   (3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase.
AN   Beta-hydroxypalmitoyl thioester dehydratase.
AN   Beta-hydroxypalmitoyl-acyl carrier protein dehydrase.
AN   Beta-hydroxypalmityl-ACP dehydrase.
AN   D-3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase.
CA   (3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] = hexadec-2-enoyl-[acyl-
CA   carrier-protein] + H(2)O.
CC   -!- Specific for 3-hydroxyacyl-[acyl-carrier-protein] derivatives C(12)
CC       to C(16) and has the highest activity on the C(16) derivative.
DR   P34731, FAS1_CANAL ;  Q9UUG0, FAS1_SCHPO ;  P34229, FAS1_YARLI ;
DR   P07149, FAS1_YEAST ;  Q71SP7, FAS_BOVIN  ;  P12276, FAS_CHICK  ;
DR   P49327, FAS_HUMAN  ;  P19096, FAS_MOUSE  ;  P12785, FAS_RAT    ;
DR   Q92215, TOXC_COCCA ;
//
ID   4.2.1.62
DE   5-alpha-hydroxysteroid dehydratase.
CA   5-alpha-ergosta-7,22-diene-3-beta,5-diol = ergosterol + H(2)O.
//
ID   4.2.1.63
DE   Transferred entry: 3.3.2.9 and 3.3.2.10.
//
ID   4.2.1.64
DE   Transferred entry: 3.3.2.9 and 3.3.2.10.
//
ID   4.2.1.65
DE   3-cyanoalanine hydratase.
CA   L-asparagine = 3-cyanoalanine + H(2)O.
//
ID   4.2.1.66
DE   Cyanide hydratase.
AN   Formamide hydro-lyase.
CA   Formamide = cyanide + H(2)O.
PR   PROSITE; PDOC00712;
PR   PROSITE; PDOC50263;
DR   P32963, CYHY_GIBBA ;  P32964, CYHY_GLOSO ;
//
ID   4.2.1.67
DE   D-fuconate dehydratase.
CA   D-fuconate = 2-dehydro-3-deoxy-D-fuconate + H(2)O.
CC   -!- Also acts on L-arabinonate.
//
ID   4.2.1.68
DE   L-fuconate dehydratase.
CA   L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H(2)O.
CC   -!- Also acts, slowly, on D-arabinonate.
//
ID   4.2.1.69
DE   Cyanamide hydratase.
CA   Urea = cyanamide + H(2)O.
DR   P22143, CYAH_MYRVE ;
//
ID   4.2.1.70
DE   Pseudouridylate synthase.
AN   Pseudouridine synthase.
AN   Uracil hydrolyase.
CA   Uracil + D-ribose 5-phosphate = pseudouridine 5'-phosphate + H(2)O.
CC   -!- Families of enzymes that forms pseudouridine in all kinds of RNA from
CC       eubacteria, archaea and eukaryotes.
PR   PROSITE; PDOC00869;
PR   PROSITE; PDOC00885;
//
ID   4.2.1.71
DE   Transferred entry: 4.2.1.27.
//
ID   4.2.1.72
DE   Transferred entry: 4.1.1.78.
//
ID   4.2.1.73
DE   Protoaphin-aglucone dehydratase (cyclizing).
CA   Protoaphin aglucone = xanthoaphin + H(2)O.
CC   -!- The product is converted non-enzymically to erythroaphin, an aphid
CC       pigment.
//
ID   4.2.1.74
DE   Long-chain-enoyl-CoA hydratase.
CA   (3S)-3-hydroxyacyl-CoA = trans-2-enoyl-CoA + H(2)O.
CC   -!- Acts in the reverse direction.
CC   -!- The best substrate is oct-3-enoyl-CoA.
CC   -!- Unlike EC 4.2.1.17 does not act on crotonoyl-CoA.
//
ID   4.2.1.75
DE   Uroporphyrinogen-III synthase.
AN   Hydroxymethylbilane hydro-lyase (cyclizing).
AN   Uroporphyrinogen-III cosynthase.
AN   Uroporphyrinogen-III cosynthetase.
CA   Hydroxymethylbilane = uroporphyrinogen III + H(2)O.
CC   -!- In the presence of EC 2.5.1.61, forms uroporphyrinogen III from
CC       porphobilinogen.
DR   O48721, HEM4_ARATH ;  O30120, HEM4_ARCFU ;  P21248, HEM4_BACSU ;
DR   Q59335, HEM4_CHLP8 ;  Q8KCJ3, HEM4_CHLTE ;  Q59294, HEM4_CLOJO ;
DR   P09126, HEM4_ECOLI ;  P10746, HEM4_HUMAN ;  Q58401, HEM4_METJA ;
DR   O26268, HEM4_METTH ;  P51163, HEM4_MOUSE ;  Q10QR9, HEM4_ORYSJ ;
DR   Q59683, HEM4_PROMI ;  P48246, HEM4_PSEAE ;  Q9L6Q3, HEM4_SALTY ;
DR   P87214, HEM4_SCHPO ;  P42452, HEM4_SYNE7 ;  P06174, HEM4_YEAST ;
//
ID   4.2.1.76
DE   UDP-glucose 4,6-dehydratase.
CA   UDP-glucose = UDP-4-dehydro-6-deoxy-D-glucose + H(2)O.
//
ID   4.2.1.77
DE   Trans-L-3-hydroxyproline dehydratase.
CA   Trans-L-3-hydroxyproline = Delta(1)-pyrroline 2-carboxylate + H(2)O.
CC   -!- Highly specific.
CC   -!- 2,3-dehydroproline is an intermediate.
//
ID   4.2.1.78
DE   (S)-norcoclaurine synthase.
AN   (S)-norlaudanosoline synthase.
CA   4-(2-aminoethyl)benzene-1,2-diol + 4-hydroxyphenylacetaldehyde = (S)-
CA   norcoclaurine + H(2)O.
CC   -!- The reaction makes a 6-membered ring by forming a bond between C-6 of
CC       the 3,4-dihydroxyphenyl group of the dopamine and C-1 of the aldehyde
CC       in the imine formed between the substrates.
CC   -!- The product is the precursor of the benzylisoquinoline alkaloids in
CC       plants.
CC   -!- Will also catalyze the reaction of 4-(2-aminoethyl)benzene-1,2-diol +
CC       (3,4-dihydroxyphenyl)acetaldehyde to form (S)-norlaudanosoline,
CC       but this alkaloid has not been found to occur in plants.
PR   PROSITE; PDOC51471;
DR   A2A1A0, NCS1_COPJA ;  A2A1A1, NCS2_COPJA ;  Q67A25, NCS_THLFG  ;
//
ID   4.2.1.79
DE   2-methylcitrate dehydratase.
AN   2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase.
AN   2-methylcitrate hydro-lyase.
CA   (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate = (Z)-but-2-ene-1,2,3-
CA   tricarboxylate + H(2)O.
CC   -!- Not identical with EC 4.2.1.4.
CC   -!- Specific for (2S,3S)-methylcitrate, showing no activity with (2R,3S)-
CC       methylcitrate.
CC   -!- Can also use cis-aconitate as a substrate but more slowly.
CC   -!- Both this enzyme and EC 4.2.1.3 are required to complete the
CC       isomerization of (2S,3S)-methylcitrate to (2R,3S)-2-methylisocitrate.
DR   Q8NSH9, PRPD1_CORGL;  Q8NSL3, PRPD2_CORGL;  P45859, PRPD_BACSU ;
DR   Q54IJ0, PRPD_DICDI ;  Q8X693, PRPD_ECO57 ;  P77243, PRPD_ECOLI ;
DR   Q8Z903, PRPD_SALTI ;  P74840, PRPD_SALTY ;  Q12428, PRPD_YEAST ;
//
ID   4.2.1.80
DE   2-oxopent-4-enoate hydratase.
AN   2-keto-4-pentenoate hydratase.
AN   OEH.
CA   4-hydroxy-2-oxopentanoate = 2-oxopent-4-enoate + H(2)O.
CC   -!- Also acts, more slowly, on cis-2-oxohex-4-enoate, but not on the
CC       trans-isomer.
DR   Q9KWS4, AMNF_PSESP ;  Q47HM0, MHPD1_DECAR;  Q400K2, MHPD1_PSEPU;
DR   Q47GC8, MHPD2_DECAR;  Q49KF9, MHPD2_PSEPU;  Q706S1, MHPD3_PSEPU;
DR   C1DRI8, MHPD_AZOVD ;  B2JQV8, MHPD_BURP8 ;  A4JPX9, MHPD_BURVG ;
DR   Q13VU0, MHPD_BURXL ;  Q9S156, MHPD_COMTE ;  A7ZI97, MHPD_ECO24 ;
DR   B7L506, MHPD_ECO55 ;  Q8XEC1, MHPD_ECO57 ;  B5Z2Q5, MHPD_ECO5E ;
DR   B7NK05, MHPD_ECO7I ;  B7MPB7, MHPD_ECO81 ;  B7M2Z8, MHPD_ECO8A ;
DR   A7ZWZ7, MHPD_ECOHS ;  P77608, MHPD_ECOLI ;  B7N8Q7, MHPD_ECOLU ;
DR   B1LIN5, MHPD_ECOSM ;  A6TAC6, MHPD_KLEP7 ;  Q3Z556, MHPD_SHISS ;
//
ID   4.2.1.81
DE   D(-)-tartrate dehydratase.
CA   (S,S)-tartrate = oxaloacetate + H(2)O.
CF   Iron.
//
ID   4.2.1.82
DE   Xylonate dehydratase.
AN   D-xylo-aldonate dehydratase.
CA   D-xylonate = 2-dehydro-3-deoxy-D-xylonate + H(2)O.
//
ID   4.2.1.83
DE   4-oxalmesaconate hydratase.
AN   4-carboxy-2-oxohexenedioate hydratase.
CA   2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = 2-hydroxy-4-carboxyhexa-2,4-
CA   dienedioate + H(2)O.
CC   -!- This enzyme participates in the degradation of protocatechuate (via
CC       the meta-cleavage pathway), syringate and gallate.
CC   -!- It accepts the enol-form of 4-oxalomesaconate, 2-hydroxy-4-carboxy-
CC       hexa-2,4-dienedioate.
//
ID   4.2.1.84
DE   Nitrile hydratase.
AN   Nitrilase.
AN   Nitrile hydro-lyase.
CA   An aliphatic amide = a nitrile + H(2)O.
CC   -!- Acts on short-chain aliphatic nitriles, converting them into the
CC       corresponding acid amides.
CC   -!- Does not act on these amides or on aromatic nitriles (cf.
CC       EC 3.5.5.1).
DR   P21219, NHA1_RHORH ;  P29378, NHA2_RHORH ;  A9V2C1, NHAAB_MONBE;
DR   P27764, NHAA_PSECL ;  P97051, NHAA_PSEPU ;  Q7SID2, NHAA_PSETH ;
DR   P13448, NHAA_RHOER ;  Q53118, NHAA_RHOSO ;  P27763, NHAB_PSECL ;
DR   P97052, NHAB_PSEPU ;  Q7SID3, NHAB_PSETH ;  P13449, NHAB_RHOER ;
DR   Q53117, NHAB_RHOSO ;  P21220, NHB1_RHORH ;  P29379, NHB2_RHORH ;
//
ID   4.2.1.85
DE   Dimethylmaleate hydratase.
CA   (2R,3S)-2,3-dimethylmalate = dimethylmaleate + H(2)O.
CF   Iron.
CC   -!- Inhibited by oxygen.
CC   -!- Forms part of the nicotinate-fermentation catabolism pathway in
CC       Eubacterium barkeri.
CC   -!- Other enzymes involved in this pathway are EC 1.17.5.1, EC 1.3.7.1,
CC       EC 3.5.2.18, EC 1.1.1.291, EC 5.4.99.4, EC 5.3.3.6 and EC 4.1.3.32.
DR   Q0QLE2, DMDA_EUBBA ;  Q0QLE1, DMDB_EUBBA ;
//
ID   4.2.1.86
DE   Transferred entry: 4.2.1.98.
//
ID   4.2.1.87
DE   Octopamine dehydratase.
CA   1-(4-hydroxyphenyl)-2-aminoethanol = (4-hydroxyphenyl)acetaldehyde +
CA   NH(3).
CC   -!- The enzyme-catalyzed reaction is believed to be dehydration to an
CC       enamine, which is spontaneously hydrolyzed to an aldehyde and
CC       ammonia.
//
ID   4.2.1.88
DE   Synephrine dehydratase.
CA   1-(4-hydroxyphenyl)-2-(methylamino)ethanol =
CA   (4-hydroxyphenyl)acetaldehyde + methylamine.
CC   -!- Removal of H(2)O from (+-)-synephrine produces a 2,3-enamine, which
CC       hydrolyzes to the products shown in the reaction above.
CC   -!- The enzyme from Arthrobacter synephrinum is highly specific.
//
ID   4.2.1.89
DE   Carnitine dehydratase.
AN   L-carnitine dehydratase.
CA   L-carnitine = 4-(trimethylammonio)but-2-enoate + H(2)O.
//
ID   4.2.1.90
DE   L-rhamnonate dehydratase.
CA   L-rhamnonate = 2-dehydro-3-deoxy-L-rhamnonate + H(2)O.
DR   A8I5F1, RHMD_AZOC5 ;  B1YMY4, RHMD_BURA4 ;  Q1BGJ0, RHMD_BURCA ;
DR   B1KAV6, RHMD_BURCC ;  A0KDV2, RHMD_BURCH ;  Q0BA70, RHMD_BURCM ;
DR   B2JLI8, RHMD_BURP8 ;  B2TFM7, RHMD_BURPP ;  Q13LW5, RHMD_BURXL ;
DR   A8MA91, RHMD_CALMQ ;  A9BQY2, RHMD_DELAS ;  B7UFQ9, RHMD_ECO27 ;
DR   B7MG14, RHMD_ECO45 ;  Q8XE07, RHMD_ECO57 ;  B7MXS8, RHMD_ECO81 ;
DR   C4ZU89, RHMD_ECOBW ;  B1X8W0, RHMD_ECODH ;  A8A2B3, RHMD_ECOHS ;
DR   A1AD99, RHMD_ECOK1 ;  Q0TFJ5, RHMD_ECOL5 ;  Q8FFM8, RHMD_ECOL6 ;
DR   B1IXU0, RHMD_ECOLC ;  P77215, RHMD_ECOLI ;  B1LLK1, RHMD_ECOSM ;
DR   Q1R9G8, RHMD_ECOUT ;  B5XNY1, RHMD_KLEP3 ;  A6TBU8, RHMD_KLEP7 ;
DR   Q12DF1, RHMD_POLSJ ;  A4FLW9, RHMD_SACEN ;  B5EZH0, RHMD_SALA4 ;
DR   Q57M62, RHMD_SALCH ;  B5FNT1, RHMD_SALDC ;  B5R264, RHMD_SALEP ;
DR   B5RCB6, RHMD_SALG2 ;  B4TBF8, RHMD_SALHS ;  B4SYW3, RHMD_SALNS ;
DR   Q5PIM9, RHMD_SALPA ;  A9N5C2, RHMD_SALPB ;  C0Q077, RHMD_SALPC ;
DR   B5BCQ4, RHMD_SALPK ;  B4TPH4, RHMD_SALSV ;  Q8Z548, RHMD_SALTI ;
DR   Q8ZNF9, RHMD_SALTY ;  Q31Z80, RHMD_SHIBS ;  Q3YZV9, RHMD_SHISS ;
DR   C4LDK0, RHMD_TOLAT ;  A1WFL2, RHMD_VEREI ;
//
ID   4.2.1.91
DE   Arogenate dehydratase.
AN   Carboxycyclohexadienyl dehydratase.
CA   L-arogenate = L-phenylalanine + H(2)O + CO(2).
CC   -!- Also acts on prephenate and D-prephenyllactate.
CC   -!- Cf. EC 4.2.1.51.
PR   PROSITE; PDOC00798;
DR   Q9SA96, AROD1_ARATH;  Q9SSE7, AROD2_ARATH;  Q9ZUY3, AROD3_ARATH;
DR   O22241, AROD4_ARATH;  Q9FNJ8, AROD5_ARATH;  Q9SGD6, AROD6_ARATH;
DR   Q01269, PHEC_PSEAE ;
//
ID   4.2.1.92
DE   Hydroperoxide dehydratase.
AN   Allene oxide synthase.
AN   AOS.
AN   Hydroperoxide isomerase.
CA   (9Z,11E,15Z)-(13S)-hydroperoxyoctadeca-9,11,15-trienoate = (9Z,15Z)-
CA   (13S)-12,13-epoxyoctadeca-9,11,15-trienoate + H(2)O.
CF   Heme-thiolate.
CC   -!- Acts on a number of unsaturated fatty-acid hydroperoxides, forming
CC       the corresponding allene oxides.
CC   -!- The product of the above reaction is unstable and is acted upon by
CC       EC 5.3.99.6 to form the cyclopentenone derivative (15Z)-12-oxophyto-
CC       10,15-dienoate (OPDA), which is the first cyclic and biologically
CC       active metabolite in the jasmonate biosynthesis pathway.
PR   PROSITE; PDOC00081;
DR   O16025, AOSL_PLEHO ;  Q7Y0C8, C74A1_ORYSJ;  Q7XYS3, C74A2_ORYSJ;
DR   Q40778, C74A2_PARAR;  Q6Z6L1, C74A3_ORYSJ;  Q6Z6K9, C74A4_ORYSJ;
DR   Q96242, CP74A_ARATH;  P48417, CP74_LINUS ;
//
ID   4.2.1.93
DE   ATP-dependent NAD(P)H-hydrate dehydratase.
AN   ATP-dependent H(4)NAD(P)OH dehydratase.
CA   ATP + (6S)-6-beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine
CA   dinucleotide = ADP + phosphate + NADH.
CC   -!- Also acts on hydrated NADPH.
CC   -!- NADH spontaneously hydrates to both (6S)- and (6R)- compounds,
CC       and these spontaneously interconvert.
CC   -!- Hence EC 4.2.1.93 can convert the whole mixture into NADH.
//
ID   4.2.1.94
DE   Scytalone dehydratase.
CA   Scytalone = 1,3,8-trihydroxynaphthalene + H(2)O.
CC   -!- Involved with EC 1.1.1.252 in the biosynthesis of melanin in
CC       pathogenic fungi.
DR   O14434, SCYD_ASPFU ;  Q00455, SCYD_GLOLA ;  P56221, SCYD_MAGO7 ;
//
ID   4.2.1.95
DE   Kievitone hydratase.
CA   Kievitone hydrate = kievitone + H(2)O.
CC   -!- The enzyme from Fusarium sp. hydrates the methylbutenyl side chain of
CC       the isoflavonoid phytoalexins, thus reducing their toxicity.
//
ID   4.2.1.96
DE   4a-hydroxytetrahydrobiopterin dehydratase.
AN   4-alpha-hydroxy-tetrahydropterin dehydratase.
AN   Pterin-4-alpha-carbinolamine dehydratase.
AN   Tetrahydrobiopterin dehydratase.
CA   (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-
CA   4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-
CA   6H-pterin + H(2)O.
CC   -!- Catalyzes the dehydration of 4a-hydroxytetrahydrobiopterins.
DR   Q475Y4, PHS1_CUPPJ ;  Q7NM43, PHS1_GLOVI ;  Q9DG45, PHS2_CHICK ;
DR   Q46VT8, PHS2_CUPPJ ;  Q7NK35, PHS2_GLOVI ;  Q9H0N5, PHS2_HUMAN ;
DR   Q9CZL5, PHS2_MOUSE ;  Q5R7K1, PHS2_PONAB ;  A1TND7, PHS_ACIAC  ;
DR   Q1IP68, PHS_ACIBL  ;  C1F425, PHS_ACIC5  ;  A5FWK8, PHS_ACICJ  ;
DR   A0KJG4, PHS_AERHH  ;  A4SNJ1, PHS_AERS4  ;  B9JCJ2, PHS_AGRRK  ;
DR   Q8UC22, PHS_AGRT5  ;  B9JUA0, PHS_AGRVS  ;  A6TVX6, PHS_ALKMQ  ;
DR   B4RXT2, PHS_ALTMD  ;  Q3MA60, PHS_ANAVT  ;  O66462, PHS_AQUAE  ;
DR   Q5P905, PHS_AROAE  ;  A1K7V8, PHS_AZOSB  ;  C1DQH9, PHS_AZOVD  ;
DR   P61732, PHS_BDEBA  ;  Q2KXB6, PHS_BORA1  ;  Q7WG14, PHS_BORBR  ;
DR   Q7W4J0, PHS_BORPA  ;  Q7VU17, PHS_BORPE  ;  Q3ZBD3, PHS_BOVIN  ;
DR   Q89WZ6, PHS_BRAJA  ;  A5E8P9, PHS_BRASB  ;  A4YJY8, PHS_BRASO  ;
DR   B2S7X9, PHS_BRUA1  ;  Q2YNV0, PHS_BRUA2  ;  Q57FT6, PHS_BRUAB  ;
DR   A9M6T4, PHS_BRUC2  ;  C0RGE2, PHS_BRUMB  ;  P65722, PHS_BRUME  ;
DR   A5VN26, PHS_BRUO2  ;  B0CIJ4, PHS_BRUSI  ;  P65723, PHS_BRUSU  ;
DR   B1YQ64, PHS_BURA4  ;  B1K1I7, PHS_BURCC  ;  A0K2V4, PHS_BURCH  ;
DR   B4E566, PHS_BURCJ  ;  Q0BJP4, PHS_BURCM  ;  A9AJD5, PHS_BURM1  ;
DR   Q62FU4, PHS_BURMA  ;  Q3JXT0, PHS_BURP1  ;  B2T7M8, PHS_BURPP  ;
DR   Q63PF1, PHS_BURPS  ;  Q39L06, PHS_BURS3  ;  A4JA07, PHS_BURVG  ;
DR   Q13SM2, PHS_BURXL  ;  Q9TZH6, PHS_CAEEL  ;  B8GYB5, PHS_CAUCN  ;
DR   Q9ABI2, PHS_CAUCR  ;  B0T207, PHS_CAUSK  ;  O73930, PHS_CHICK  ;
DR   A9WI69, PHS_CHLAA  ;  B8G3F7, PHS_CHLAD  ;  B3ECB9, PHS_CHLL2  ;
DR   B3QQ83, PHS_CHLP8  ;  B9LCC8, PHS_CHLSY  ;  Q8KFI4, PHS_CHLTE  ;
DR   Q1QXY2, PHS_CHRSD  ;  Q7NVH7, PHS_CHRVO  ;  Q47XN8, PHS_COLP3  ;
DR   B8HU56, PHS_CYAP4  ;  Q11PN9, PHS_CYTH3  ;  Q47IX1, PHS_DECAR  ;
DR   Q54RY8, PHS_DICDI  ;  A8LKP0, PHS_DINSH  ;  O76454, PHS_DROME  ;
DR   P58249, PHS_DROVI  ;  A0M1H4, PHS_GRAFK  ;  Q2SCE8, PHS_HAHCH  ;
DR   A1WWH9, PHS_HALHL  ;  B9LPE3, PHS_HALLT  ;  Q5V1I9, PHS_HALMA  ;
DR   B0R6B9, PHS_HALS3  ;  Q9HP73, PHS_HALSA  ;  A9AXS2, PHS_HERA2  ;
DR   P61457, PHS_HUMAN  ;  P0C8L6, PHS_HYPDU  ;  Q5QU19, PHS_IDILO  ;
DR   Q28VA7, PHS_JANSC  ;  Q5X3Q4, PHS_LEGPA  ;  A5IDI1, PHS_LEGPC  ;
DR   Q5ZU09, PHS_LEGPH  ;  Q5WV42, PHS_LEGPL  ;  A1TZA3, PHS_MARAV  ;
DR   A6VSD2, PHS_MARMS  ;  Q11D07, PHS_MESSB  ;  Q60BH8, PHS_METCA  ;
DR   A4YEM3, PHS_METS5  ;  B0JQV0, PHS_MICAN  ;  P61458, PHS_MOUSE  ;
DR   A0QCA6, PHS_MYCA1  ;  B1MLG8, PHS_MYCA9  ;  P0A5S3, PHS_MYCBO  ;
DR   A1KHV0, PHS_MYCBP  ;  C1AMF4, PHS_MYCBT  ;  B8ZRQ6, PHS_MYCLB  ;
DR   Q9CBX1, PHS_MYCLE  ;  P61733, PHS_MYCPA  ;  A0R2K7, PHS_MYCS2  ;
DR   A3Q4G7, PHS_MYCSJ  ;  A1UKF3, PHS_MYCSK  ;  Q1B4N5, PHS_MYCSS  ;
DR   A5U1K8, PHS_MYCTA  ;  P0A5S2, PHS_MYCTU  ;  A1TDS4, PHS_MYCVP  ;
DR   Q3ISB3, PHS_NATPD  ;  Q0ADS7, PHS_NITEC  ;  Q82Y13, PHS_NITEU  ;
DR   Q1QHE0, PHS_NITHX  ;  Q2YB52, PHS_NITMU  ;  Q3J910, PHS_NITOC  ;
DR   Q3SNS9, PHS_NITWN  ;  Q5YQC8, PHS_NOCFA  ;  B2IVV2, PHS_NOSP7  ;
DR   Q8YNL6, PHS_NOSS1  ;  Q2G9B0, PHS_NOVAD  ;  A6WV21, PHS_OCHA4  ;
DR   B6JAT9, PHS_OLICO  ;  B1ZY08, PHS_OPITP  ;  A1B3I3, PHS_PARDP  ;
DR   A7HSX5, PHS_PARL1  ;  Q3A282, PHS_PELCD  ;  Q3B6N5, PHS_PELLD  ;
DR   B4SAU0, PHS_PELPB  ;  B4RBN1, PHS_PHEZH  ;  Q6LI45, PHS_PHOPR  ;
DR   A3PBL6, PHS_PROM0  ;  A8G3K7, PHS_PROM2  ;  A2C7K4, PHS_PROM3  ;
DR   A2BVF3, PHS_PROM5  ;  Q31C42, PHS_PROM9  ;  Q7VD93, PHS_PROMA  ;
DR   Q7V689, PHS_PROMM  ;  Q7V2I5, PHS_PROMP  ;  A2BPX4, PHS_PROMS  ;
DR   Q46GT1, PHS_PROMT  ;  Q48G05, PHS_PSE14  ;  A6VAA4, PHS_PSEA7  ;
DR   B7UY63, PHS_PSEA8  ;  Q02I31, PHS_PSEAB  ;  P43335, PHS_PSEAE  ;
DR   Q1I6Y2, PHS_PSEE4  ;  Q4KG97, PHS_PSEF5  ;  C3K0W5, PHS_PSEFS  ;
DR   Q3IIZ3, PHS_PSEHT  ;  A5W0C1, PHS_PSEP1  ;  Q3KG65, PHS_PSEPF  ;
DR   B0KRW3, PHS_PSEPG  ;  Q88EH2, PHS_PSEPK  ;  B1JCI6, PHS_PSEPW  ;
DR   Q885L1, PHS_PSESM  ;  Q4ZQG4, PHS_PSEU2  ;  A4VQE0, PHS_PSEU5  ;
DR   Q4FVF3, PHS_PSYA2  ;  A1SSU3, PHS_PSYIN  ;  B2UGY6, PHS_RALPJ  ;
DR   Q8XU38, PHS_RALSO  ;  P61459, PHS_RAT    ;  Q2K3A7, PHS_RHIEC  ;
DR   Q1MAM8, PHS_RHIL3  ;  Q98E92, PHS_RHILO  ;  B5ZTF5, PHS_RHILW  ;
DR   Q92L66, PHS_RHIME  ;  C3MAI8, PHS_RHISN  ;  Q2J3Z9, PHS_RHOP2  ;
DR   Q07N39, PHS_RHOP5  ;  P61734, PHS_RHOPA  ;  Q214W1, PHS_RHOPB  ;
DR   Q13D98, PHS_RHOPS  ;  B3Q9E4, PHS_RHOPT  ;  Q2RNC0, PHS_RHORT  ;
DR   Q3IZF4, PHS_RHOS4  ;  A8GYB5, PHS_RICB8  ;  Q1RGM6, PHS_RICBR  ;
DR   A8EXY4, PHS_RICCK  ;  Q4UKS5, PHS_RICFE  ;  A7NS25, PHS_ROSCS  ;
DR   Q16BN1, PHS_ROSDO  ;  A5UPS5, PHS_ROSS1  ;  Q1AUE0, PHS_RUBXD  ;
DR   Q21MC6, PHS_SACD2  ;  O42658, PHS_SCHPO  ;  A1S7S0, PHS_SHEAM  ;
DR   B8E7N1, PHS_SHEB2  ;  A3D2P0, PHS_SHEB5  ;  A6WLE1, PHS_SHEB8  ;
DR   A9KVE9, PHS_SHEB9  ;  Q12L03, PHS_SHEDO  ;  Q084Y3, PHS_SHEFN  ;
DR   B0TNB2, PHS_SHEHH  ;  A3QCV5, PHS_SHELP  ;  Q8EGD7, PHS_SHEON  ;
DR   A8H2I7, PHS_SHEPA  ;  A4Y581, PHS_SHEPC  ;  B8CLA1, PHS_SHEPW  ;
DR   A0KYY8, PHS_SHESA  ;  Q0HGZ0, PHS_SHESM  ;  Q0HT97, PHS_SHESR  ;
DR   A1RLI8, PHS_SHESW  ;  B1KMK3, PHS_SHEWM  ;  Q5LM31, PHS_SILPO  ;
DR   Q1GDR0, PHS_SILST  ;  A6UE17, PHS_SINMW  ;  Q01VX3, PHS_SOLUE  ;
DR   A5V667, PHS_SPHWW  ;  Q82M02, PHS_STRAW  ;  O86722, PHS_STRCO  ;
DR   B4SPV4, PHS_STRM5  ;  B2FM88, PHS_STRMK  ;  Q4J6J6, PHS_SULAC  ;
DR   C3MZU9, PHS_SULIA  ;  C4KJC1, PHS_SULIK  ;  C3MTL3, PHS_SULIM  ;
DR   Q97WM6, PHS_SULSO  ;  Q96YL0, PHS_SULTO  ;  B1XN71, PHS_SYNP2  ;
DR   A5GMR6, PHS_SYNPW  ;  Q7U5B3, PHS_SYNPX  ;  Q0I8H5, PHS_SYNS3  ;
DR   P73790, PHS_SYNY3  ;  Q8DHW8, PHS_THEEB  ;  B9L1Y8, PHS_THERP  ;
DR   Q31HZ6, PHS_THICR  ;  Q3SHT9, PHS_THIDA  ;  Q116J2, PHS_TRIEI  ;
DR   A5F0J0, PHS_VIBC3  ;  Q9KLB9, PHS_VIBCH  ;  C3LW91, PHS_VIBCM  ;
DR   A7N3S9, PHS_VIBHB  ;  Q87IM9, PHS_VIBPA  ;  Q8D6S1, PHS_VIBVU  ;
DR   Q7MDN2, PHS_VIBVY  ;  Q8PKQ3, PHS_XANAC  ;  Q3BSV4, PHS_XANC5  ;
DR   Q4UUW5, PHS_XANC8  ;  B0RTH5, PHS_XANCB  ;  Q8P8Z8, PHS_XANCP  ;
DR   Q2P1A2, PHS_XANOM  ;  B2STN6, PHS_XANOP  ;  Q5GYA0, PHS_XANOR  ;
DR   Q91901, PHS_XENLA  ;  B2I9W6, PHS_XYLF2  ;  Q9PAB4, PHS_XYLFA  ;
DR   B0U5V4, PHS_XYLFM  ;  Q87A51, PHS_XYLFT  ;  P38744, PHS_YEAST  ;
//
ID   4.2.1.97
DE   Phaseollidin hydratase.
CA   Phaseollidin hydrate = phaseollidin + H(2)O.
CC   -!- The enzyme from Fusarium solani, which is distinct from EC 4.2.1.95,
CC       hydrates the methylbutenyl side-chain of the isoflavonoid
CC       phytoalexin, phaseollidin.
//
ID   4.2.1.98
DE   16-alpha-hydroxyprogesterone dehydratase.
AN   16-alpha-dehydroxylase.
AN   16-alpha-hydroxyprogesterone dehydroxylase.
AN   16-dehydroprogesterone hydratase.
AN   Hydroxyprogesterone dehydroxylase.
CA   16-alpha-hydroxyprogesterone = 16,17-didehydroprogesterone + H(2)O.
CC   -!- 16-alpha-hydroxypregnenolone is also a substrate.
CC   -!- Formerly EC 4.2.1.86.
//
ID   4.2.1.99
DE   2-methylisocitrate dehydratase.
AN   (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase.
CA   (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = (Z)-but-2-ene-1,2,3-
CA   tricarboxylate + H(2)O.
CC   -!- The enzyme from the fungus Yarrowia lipolytica does not act on
CC       isocitrate.
DR   P36683, ACON2_ECOLI;  Q9ZL64, ACON2_HELPJ;  P56418, ACON2_HELPY;
DR   Q9I2V5, ACON2_PSEAE;  P74582, ACON2_SYNY3;
//
ID   4.2.1.100
DE   Cyclohexa-1,5-dienecarbonyl-CoA hydratase.
AN   Cyclohexa-1,5-diene-1-carbonyl-CoA hydratase.
AN   Cyclohexa-1,5-diene-1-carboxyl-CoA hydratase.
AN   Dienoyl-CoA hydratase.
CA   6-hydroxycyclohex-1-enecarbonyl-CoA = cyclohexa-1,5-dienecarbonyl-CoA +
CA   H(2)O.
CC   -!- Forms part of the anaerobic benzoate degradation pathway, which also
CC       includes EC 1.3.99.7, EC 1.3.7.8 and EC 4.2.1.55.
CC   -!- Formerly EC 4.2.1.102.
DR   O87873, DCH_THAAR  ;
//
ID   4.2.1.101
DE   Trans-feruloyl-CoA hydratase.
AN   4-hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA hydro-lyase (trans-
AN   feruloyl-CoA-forming).
CA   4-hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA = feruloyl-CoA +
CA   H(2)O.
//
ID   4.2.1.102
DE   Transferred entry: 4.2.1.100.
//
ID   4.2.1.103
DE   Cyclohexyl-isocyanide hydratase.
AN   Isonitrile hydratase.
CA   N-cyclohexylformamide = cyclohexyl isocyanide + H(2)O.
CC   -!- The enzyme from Pseudomonas putida strain N19-2 can also catalyze the
CC       hydration of other isonitriles to the corresponding N-substituted
CC       formamides.
CC   -!- The enzyme has no metal requirements.
//
ID   4.2.1.104
DE   Cyanase.
AN   Cyanate aminohydrolase.
AN   Cyanate C-N-lyase.
AN   Cyanate hydratase.
AN   Cyanate hydrolase.
AN   Cyanate lyase.
CA   Cyanate + HCO(3)(-) + 2 H(+) = NH(3) + 2 CO(2).
CC   -!- This enzyme, which is found in bacteria and plants, is used to
CC       decompose cyanate, which can be used as the sole source of nitrogen.
CC   -!- The reaction can be considered as the reverse of 'carbamate = cyanate
CC       + H(2)O', where this is assisted by reaction with bicarbonate and
CC       carbon dioxide, and hence is classified in sub-subclass 4.2.1.
CC   -!- Bicarbonate functions as a recycling substrate.
CC   -!- Formerly EC 3.5.5.3 and EC 4.3.99.1.
DR   B9NJI2, CYNS1_POPTR;  B9HSR7, CYNS2_POPTR;  B0C8H2, CYNS_ACAM1 ;
DR   C0NWE3, CYNS_AJECG ;  C6HBW5, CYNS_AJECH ;  A6R853, CYNS_AJECN ;
DR   C5G6H8, CYNS_AJEDR ;  C5JJW0, CYNS_AJEDS ;  Q3M8R1, CYNS_ANAVT ;
DR   O66587, CYNS_AQUAE ;  O22683, CYNS_ARATH ;  C5FMD4, CYNS_ARTOC ;
DR   A1C7Y5, CYNS_ASPCL ;  B0XV83, CYNS_ASPFC ;  B8NQ08, CYNS_ASPFN ;
DR   Q4WZL3, CYNS_ASPFU ;  A2R692, CYNS_ASPNC ;  Q2UAX9, CYNS_ASPOR ;
DR   Q0CVK8, CYNS_ASPTN ;  A6S6V7, CYNS_BOTFB ;  B1Z5U9, CYNS_BURA4 ;
DR   Q1BL48, CYNS_BURCA ;  B1K759, CYNS_BURCC ;  A0AXK2, CYNS_BURCH ;
DR   B4EJC2, CYNS_BURCJ ;  Q0B2Y2, CYNS_BURCM ;  A3MRF1, CYNS_BURM7 ;
DR   A2S5L0, CYNS_BURM9 ;  Q62H08, CYNS_BURMA ;  A1V0I2, CYNS_BURMS ;
DR   A3NZD0, CYNS_BURP0 ;  A3NDL7, CYNS_BURP6 ;  Q63QS4, CYNS_BURPS ;
DR   Q391E0, CYNS_BURS3 ;  Q2SZA4, CYNS_BURTA ;  A4JRR6, CYNS_BURVG ;
DR   Q4JJB1, CYNS_CHAGS ;  Q7NWU9, CYNS_CHRVO ;  C5PDS9, CYNS_COCP7 ;
DR   A8NV38, CYNS_COPC7 ;  P0CN03, CYNS_CRYNB ;  P0CN02, CYNS_CRYNJ ;
DR   Q0K572, CYNS_CUPNH ;  Q47G40, CYNS_DECAR ;  A7ZI88, CYNS_ECO24 ;
DR   B7L4Z6, CYNS_ECO55 ;  P58704, CYNS_ECO57 ;  B5Z2P3, CYNS_ECO5E ;
DR   B7NK15, CYNS_ECO7I ;  B7M2Y9, CYNS_ECO8A ;  B1XBI8, CYNS_ECODH ;
DR   A7ZWY8, CYNS_ECOHS ;  B1J0T9, CYNS_ECOLC ;  P00816, CYNS_ECOLI ;
DR   B7N8P7, CYNS_ECOLU ;  B6HZW6, CYNS_ECOSE ;  B1LIM5, CYNS_ECOSM ;
DR   C8VCM2, CYNS_EMENI ;  B0DN41, CYNS_LACBS ;  A4R2S1, CYNS_MAGO7 ;
DR   B6TTW1, CYNS_MAIZE ;  A6W1Q1, CYNS_MARMS ;  B7FKW7, CYNS_MEDTR ;
DR   Q1GZA1, CYNS_METFK ;  A2SLJ8, CYNS_METPP ;  A0QL81, CYNS_MYCA1 ;
DR   B1ME90, CYNS_MYCA9 ;  P61192, CYNS_MYCPA ;  A1T8R2, CYNS_MYCVP ;
DR   C7YTF5, CYNS_NECH7 ;  A1DIL2, CYNS_NEOFI ;  Q871Z4, CYNS_NEUCR ;
DR   P58703, CYNS_NOSS1 ;  A2Z8F9, CYNS_ORYSI ;  Q9FWK4, CYNS_ORYSJ ;
DR   C1H765, CYNS_PARBA ;  C1FZ35, CYNS_PARBD ;  C0S4M2, CYNS_PARBP ;
DR   B6HIM5, CYNS_PENCW ;  B6Q2W9, CYNS_PENMQ ;  Q0UBT2, CYNS_PHANO ;
DR   B7FRE8, CYNS_PHATC ;  Q7NA33, CYNS_PHOLL ;  A9TND9, CYNS_PHYPA ;
DR   B2B4S6, CYNS_PODAN ;  Q12GT8, CYNS_POLSJ ;  A4SXJ6, CYNS_POLSQ ;
DR   A2BZH4, CYNS_PROM1 ;  Q7V2U0, CYNS_PROMP ;  Q46I00, CYNS_PROMT ;
DR   Q48GB5, CYNS_PSE14 ;  A6V6B1, CYNS_PSEA7 ;  B7VA51, CYNS_PSEA8 ;
DR   Q02LK0, CYNS_PSEAB ;  Q9I263, CYNS_PSEAE ;  Q1I7P9, CYNS_PSEE4 ;
DR   Q4KGL6, CYNS_PSEF5 ;  A5W5F5, CYNS_PSEP1 ;  B1JA05, CYNS_PSEPW ;
DR   Q885A6, CYNS_PSESM ;  Q4ZQQ7, CYNS_PSEU2 ;  B2WIX9, CYNS_PYRTR ;
DR   B2UK94, CYNS_RALPJ ;  Q21S14, CYNS_RHOFD ;  B9T3R0, CYNS_RICCO ;
DR   A7F1L5, CYNS_SCLS1 ;  A8GBZ7, CYNS_SERP5 ;  C5WYI7, CYNS_SORBI ;
DR   D1ZHN6, CYNS_SORMK ;  C6SXE1, CYNS_SOYBN ;  Q972W5, CYNS_SULTO ;
DR   Q59948, CYNS_SYNE7 ;  Q5N0J1, CYNS_SYNP6 ;  Q7U3E2, CYNS_SYNPX ;
DR   Q0I634, CYNS_SYNS3 ;  Q55367, CYNS_SYNY3 ;  B8MQZ4, CYNS_TALSN ;
DR   C5BUK2, CYNS_TERTT ;  B5YM03, CYNS_THAPS ;  Q3SHJ2, CYNS_THIDA ;
DR   C4JUN6, CYNS_UNCRE ;  Q4PD40, CYNS_USTMA ;  C5CRQ4, CYNS_VARPS ;
DR   C9S8A7, CYNS_VERA1 ;  A5BJL8, CYNS_VITVI ;
//
ID   4.2.1.105
DE   2-hydroxyisoflavanone dehydratase.
CA   2,7,4'-trihydroxyisoflavanone = daidzein + H(2)O.
CC   -!- Catalyzes the final step in the formation of the isoflavonoid
CC       skeleton.
CC   -!- The reaction also occurs spontaneously.
//
ID   4.2.1.106
DE   Bile-acid 7-alpha-dehydratase.
AN   BA7 alpha dehydratase.
CA   7-alpha,12-alpha-dihydroxy-3-oxochol-4-enoate = 12-alpha-hydroxy-3-
CA   oxochola-4,6-dienoate + H(2)O.
CC   -!- The enzyme from Eubacterium sp. strain VPI 12708 can also use
CC       7-alpha-hydroxy-3-oxochol-4-enoate as a substrate but not 7-alpha,12-
CC       alpha-dihydroxy-3-oxochol-5-beta-anoate, 3-alpha,7-alpha,12-alpha-
CC       trihydroxychol-5-beta-anoate or 7-beta-hydroxy-3-oxochol-4-enoate.
DR   P19412, BAIE_EUBSP ;
//
ID   4.2.1.107
DE   3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA
DE   hydratase.
AN   D-3-hydroxyacyl-CoA dehydratase.
CA   (24R,25R)-3-alpha,7-alpha,12-alpha,24-tetrahydroxy-5-beta-cholestanoyl-
CA   CoA = (24E)-3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-
CA   CoA + H(2)O.
CC   -!- Forms part of the rat peroxisomal multifunctional enzyme perMFE-2,
CC       which also exhibits a dehydrogenase activity.
CC   -!- Involved in the beta-oxidation of the cholesterol side chain in the
CC       cholic-acid biosynthesis pathway.
DR   P51659, DHB4_HUMAN ;  P51660, DHB4_MOUSE ;  P97852, DHB4_RAT   ;
//
ID   4.2.1.108
DE   Ectoine synthase.
AN   L-ectoine synthase.
AN   N-acetyldiaminobutanoate dehydratase.
AN   N-acetyldiaminobutyrate dehydratase.
CA   N(4)-acetyl-L-2,4-diaminobutanoate = L-ectoine + H(2)O.
CC   -!- Ectoine is an osmoprotectant that is found in halophilic eubacteria.
CC   -!- This is the third enzyme in the ectoine biosynthesis pathway,
CC       the other enzymes involved being EC 2.6.1.76 and EC 2.3.1.178.
DR   Q0A9E8, ECTC_ALHEH ;  Q9KED5, ECTC_BACHD ;  Q9AP33, ECTC_BACPA ;
DR   Q5WL77, ECTC_BACSK ;  Q2KY19, ECTC_BORA1 ;  Q7WHI9, ECTC_BORBR ;
DR   Q7W978, ECTC_BORPA ;  A9IJZ8, ECTC_BORPD ;  Q89TD1, ECTC_BRAJA ;
DR   Q9ZEU6, ECTC_CHRSD ;  B8F9C9, ECTC_DESAA ;  A8ZWG2, ECTC_DESOH ;
DR   Q2SLV8, ECTC_HAHCH ;  O52251, ECTC_HALED ;  Q0C1P4, ECTC_HYPNA ;
DR   O06061, ECTC_MARHA ;  A6VUG0, ECTC_MARMS ;  B1MAS5, ECTC_MYCA9 ;
DR   A4TEW9, ECTC_MYCGI ;  A1UKU2, ECTC_MYCSK ;  Q1B487, ECTC_MYCSS ;
DR   A1TFU3, ECTC_MYCVP ;  Q3JCB0, ECTC_NITOC ;  Q5YW76, ECTC_NOCFA ;
DR   Q8ESU7, ECTC_OCEIH ;  B4R981, ECTC_PHEZH ;  C1A1L0, ECTC_RHOE4 ;
DR   C1AVJ6, ECTC_RHOOB ;  Q0SH55, ECTC_RHOSR ;  Q21LH6, ECTC_SACD2 ;
DR   A4F710, ECTC_SACEN ;  Q1GNW6, ECTC_SPHAL ;  Q6QUY8, ECTC_STRAQ ;
DR   Q829L5, ECTC_STRAW ;  Q93RW0, ECTC_STRCO ;  B1W1R5, ECTC_STRGG ;
DR   C5BQN7, ECTC_TERTT ;  Q47T77, ECTC_THEFY ;  A5F0H9, ECTC_VIBC3 ;
DR   Q9KLC3, ECTC_VIBCH ;  C3LW87, ECTC_VIBCM ;  Q5DYF2, ECTC_VIBF1 ;
DR   B5EVR2, ECTC_VIBFM ;  A7MVY7, ECTC_VIBHB ;  Q87NZ8, ECTC_VIBPA ;
DR   B7VQ39, ECTC_VIBSL ;  Q6PR31, ECTC_VIRPA ;  Q7MS24, ECTC_WOLSU ;
//
ID   4.2.1.109
DE   Methylthioribulose 1-phosphate dehydratase.
AN   1-PMT-ribulose dehydratase.
CA   S-methyl-5-thio-D-ribulose 1-phosphate = 5-(methylthio)-2,3-dioxopentyl
CA   phosphate + H(2)O.
CC   -!- This enzyme forms part of the methionine salvage pathway.
DR   E0CSI1, MTBC1_VITVI;  E0CTF3, MTBC2_VITVI;  Q9FN41, MTBC_ARATH ;
DR   B4G0F3, MTBC_MAIZE ;  B8BKI7, MTBC_ORYSI ;  Q2R483, MTBC_ORYSJ ;
DR   A9RBS1, MTBC_PHYPA ;  B9N1F9, MTBC_POPTR ;  B9SQI7, MTBC_RICCO ;
DR   C6JS30, MTBC_SORBI ;  Q5YQZ6, MTNAB_NOCFA;  Q65KJ7, MTNBX_BACLD;
DR   A5FUG4, MTNB_ACICJ ;  C4WU37, MTNB_ACYPI ;  Q16NX0, MTNB_AEDAE ;
DR   C0NN25, MTNB_AJECG ;  C6H2R1, MTNB_AJECH ;  A6RAS3, MTNB_AJECN ;
DR   C5GGA4, MTNB_AJEDR ;  C5JIC2, MTNB_AJEDS ;  Q0VPK5, MTNB_ALCBS ;
DR   Q7PS09, MTNB_ANOGA ;  O67788, MTNB_AQUAE ;  C5FEJ4, MTNB_ARTOC ;
DR   Q75CP5, MTNB_ASHGO ;  A1CIK4, MTNB_ASPCL ;  B0Y4N9, MTNB_ASPFC ;
DR   B8NSW2, MTNB_ASPFN ;  Q4WQH4, MTNB_ASPFU ;  A2Q9M4, MTNB_ASPNC ;
DR   Q2UUH5, MTNB_ASPOR ;  Q0CT19, MTNB_ASPTN ;  C1DHH0, MTNB_AZOVD ;
DR   A7Z3X6, MTNB_BACA2 ;  C3P747, MTNB_BACAA ;  C3LIA8, MTNB_BACAC ;
DR   A0RI44, MTNB_BACAH ;  Q81MJ0, MTNB_BACAN ;  B7JL18, MTNB_BACC0 ;
DR   Q731R0, MTNB_BACC1 ;  B7IWF0, MTNB_BACC2 ;  C1EQR3, MTNB_BACC3 ;
DR   B7H929, MTNB_BACC4 ;  B7HN16, MTNB_BACC7 ;  A7GS62, MTNB_BACCN ;
DR   B9IWQ1, MTNB_BACCQ ;  Q819E6, MTNB_BACCR ;  Q635P1, MTNB_BACCZ ;
DR   Q6HEC7, MTNB_BACHK ;  A8FCH0, MTNB_BACP2 ;  O31668, MTNB_BACSU ;
DR   A9VFE1, MTNB_BACWK ;  A6RI12, MTNB_BOTFB ;  Q0VCJ2, MTNB_BOVIN ;
DR   A5EES6, MTNB_BRASB ;  A8WRP9, MTNB_CAEBR ;  Q23261, MTNB_CAEEL ;
DR   Q5AG73, MTNB_CANAL ;  C4YRG6, MTNB_CANAW ;  B9WHK1, MTNB_CANDC ;
DR   Q6FJA5, MTNB_CANGA ;  C5MHJ2, MTNB_CANTT ;  Q2HE69, MTNB_CHAGB ;
DR   Q5ZLP2, MTNB_CHICK ;  A8ANI0, MTNB_CITK8 ;  C4XXU2, MTNB_CLAL4 ;
DR   C5PIC1, MTNB_COCP7 ;  A8NQV9, MTNB_COPC7 ;  P0CM15, MTNB_CRYNB ;
DR   P0CM14, MTNB_CRYNJ ;  Q66I75, MTNB_DANRE ;  Q6BIX5, MTNB_DEBHA ;
DR   Q54NY7, MTNB_DICDI ;  B3MW09, MTNB_DROAN ;  B3NVZ7, MTNB_DROER ;
DR   B4JLL3, MTNB_DROGR ;  Q9VY93, MTNB_DROME ;  B4L8M2, MTNB_DROMO ;
DR   B4GY79, MTNB_DROPE ;  Q29HV4, MTNB_DROPS ;  B4IG61, MTNB_DROSE ;
DR   B4R4E9, MTNB_DROSI ;  B4M1W5, MTNB_DROVI ;  B4NEU3, MTNB_DROWI ;
DR   B4Q2F5, MTNB_DROYA ;  Q5B787, MTNB_EMENI ;  A4W7Z4, MTNB_ENT38 ;
DR   A7MK09, MTNB_ENTS8 ;  Q3ZUZ8, MTNB_ENTSA ;  Q6D1G1, MTNB_ERWCT ;
DR   C1BYA3, MTNB_ESOLU ;  B1YIY0, MTNB_EXIS2 ;  C4KZ52, MTNB_EXISA ;
DR   Q5L1E0, MTNB_GEOKA ;  C5D7V1, MTNB_GEOSW ;  A4ILL7, MTNB_GEOTN ;
DR   A9H8G1, MTNB_GLUDA ;  Q5FRJ3, MTNB_GLUOX ;  Q0BPT9, MTNB_GRABC ;
DR   Q2SKZ2, MTNB_HAHCH ;  Q96GX9, MTNB_HUMAN ;  B5XZV4, MTNB_KLEP3 ;
DR   A6T663, MTNB_KLEP7 ;  Q6CMZ9, MTNB_KLULA ;  B0CZ32, MTNB_LACBS ;
DR   C5DCA2, MTNB_LACTC ;  A4HGN7, MTNB_LEIBR ;  A4I3R0, MTNB_LEIIN ;
DR   Q4Q882, MTNB_LEIMA ;  B0SII1, MTNB_LEPBA ;  Q04NC3, MTNB_LEPBJ ;
DR   Q04WK2, MTNB_LEPBL ;  B0SU49, MTNB_LEPBP ;  Q75FG3, MTNB_LEPIC ;
DR   Q8EXC1, MTNB_LEPIN ;  A5E3E3, MTNB_LODEL ;  A4RK52, MTNB_MAGO7 ;
DR   A1TZ34, MTNB_MARAV ;  Q60AP7, MTNB_METCA ;  B0JVQ9, MTNB_MICAN ;
DR   A9VCQ2, MTNB_MONBE ;  Q9WVQ5, MTNB_MOUSE ;  D2VN51, MTNB_NAEGR ;
DR   C7YHA8, MTNB_NECH7 ;  A7RH72, MTNB_NEMVE ;  A1CW59, MTNB_NEOFI ;
DR   Q7SF46, MTNB_NEUCR ;  C1BJB1, MTNB_OSMMO ;  C1H861, MTNB_PARBA ;
DR   C1G3Q0, MTNB_PARBD ;  C0S4Z7, MTNB_PARBP ;  A7HU86, MTNB_PARL1 ;
DR   C6DCZ4, MTNB_PECCP ;  B6HNY8, MTNB_PENCW ;  B6QQ13, MTNB_PENMQ ;
DR   C0QSI8, MTNB_PERMH ;  Q0UUN6, MTNB_PHANO ;  A5DHV9, MTNB_PICGU ;
DR   C4R7D9, MTNB_PICPG ;  A3LVM9, MTNB_PICST ;  B2A8X1, MTNB_PODAN ;
DR   Q48KM8, MTNB_PSE14 ;  A6V7A8, MTNB_PSEA7 ;  B7UV38, MTNB_PSEA8 ;
DR   Q02KH3, MTNB_PSEAB ;  Q9I342, MTNB_PSEAE ;  Q3IJW1, MTNB_PSEHT ;
DR   Q3KFI9, MTNB_PSEPF ;  Q884P3, MTNB_PSESM ;  Q4ZVC0, MTNB_PSEU2 ;
DR   B2WCB2, MTNB_PYRTR ;  C1C4M8, MTNB_RANCA ;  B5X277, MTNB_SALSA ;
DR   B6K0X1, MTNB_SCHJY ;  Q9HE08, MTNB_SCHPO ;  A7EH92, MTNB_SCLS1 ;
DR   A8GAA8, MTNB_SERP5 ;  Q2NWC8, MTNB_SODGM ;  A9FCX7, MTNB_SORC5 ;
DR   D1ZJC1, MTNB_SORMK ;  B4STR2, MTNB_STRM5 ;  B2FPP4, MTNB_STRMK ;
DR   B2VAA6, MTNB_SULSY ;  B1XPT3, MTNB_SYNP2 ;  B8LXM1, MTNB_TALSN ;
DR   B3S866, MTNB_TRIAD ;  C4JKS2, MTNB_UNCRE ;  A7TET7, MTNB_VANPO ;
DR   Q8PLG0, MTNB_XANAC ;  Q3BUE6, MTNB_XANC5 ;  Q4UU51, MTNB_XANC8 ;
DR   B0RSM5, MTNB_XANCB ;  Q8P9N3, MTNB_XANCP ;  Q2P3W4, MTNB_XANOM ;
DR   B2SM82, MTNB_XANOP ;  Q5H0X8, MTNB_XANOR ;  Q6NU29, MTNB_XENLA ;
DR   Q5FW37, MTNB_XENTR ;  B2I5X2, MTNB_XYLF2 ;  Q9PBD5, MTNB_XYLFA ;
DR   B0U3A4, MTNB_XYLFM ;  Q87C38, MTNB_XYLFT ;  Q6CBB0, MTNB_YARLI ;
DR   B3LQB9, MTNB_YEAS1 ;  C7GKY0, MTNB_YEAS2 ;  B5VLI6, MTNB_YEAS6 ;
DR   A6ZPY9, MTNB_YEAS7 ;  P47095, MTNB_YEAST ;  A1JP13, MTNB_YERE8 ;
DR   A7FLL4, MTNB_YERP3 ;  B2K630, MTNB_YERPB ;  A9R2Z8, MTNB_YERPG ;
DR   A4TPN2, MTNB_YERPP ;  Q66E19, MTNB_YERPS ;  B1JIK6, MTNB_YERPY ;
DR   C5E0B9, MTNB_ZYGRC ;
//
ID   4.2.1.110
DE   Aldos-2-ulose dehydratase.
AN   1,5-anhydro-D-fructose dehydratase (microthecin-forming).
AN   AUDH.
AN   Pyranosone dehydratase.
CA   (1) 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-
CA   ulose + H(2)O.
CA   (2) 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 2-hydroxy-2-
CA   (hydroxymethyl)-2H-pyran-3(6H)-one.
CC   -!- Catalyzes two of the steps in the anhydrofructose pathway, which
CC       leads to the degradation of glycogen and starch via 1,5-anhydro-D-
CC       fructose.
CC   -!- The other enzymes involved in this pathway are EC 4.2.1.111,
CC       EC 4.2.2.13 and EC 5.3.3.15.
CC   -!- Aldose-2-uloses such as 2-dehydroglucose can also act as substrates,
CC       but more slowly.
CC   -!- A bifunctional enzyme that acts as both a lyase and as an isomerase.
CC   -!- Differs from EC 4.2.1.111, which can carry out only reaction 1 and
CC       requires a cofactor for activity.
DR   P84193, AUD_PHACH  ;
//
ID   4.2.1.111
DE   1,5-anhydro-D-fructose dehydratase.
AN   1,5-anhydro-D-arabino-hex-2-ulose dehydratase.
AN   1,5-anhydro-D-fructose 4-dehydratase.
AN   1,5-anhydro-D-fructose hydrolyase.
AN   AF dehydratase.
AN   AFDH.
CA   1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose +
CA   H(2)O.
CF   Calcium or sodium or magnesium.
CC   -!- Catalyzes one of the steps in the anhydrofructose pathway, which
CC       leads to the degradation of glycogen and starch via 1,5-anhydro-D-
CC       fructose.
CC   -!- The other enzymes involved in this pathway are EC 4.2.1.110,
CC       EC 4.2.2.13 and EC 5.3.3.15.
CC   -!- Unlike EC 4.2.1.110 the enzyme is specific for 1,5-anhydro-D-fructose
CC       as substrate and shows no activity toward aldose-2-uloses such as
CC       2-dehydroglucose; in addition, it is inhibited by its end-product
CC       ascopyrone M and it cannot convert the end-product ascopyrone M into
CC       microthecin, as can EC 4.2.1.110.
//
ID   4.2.1.112
DE   Acetylene hydratase.
AN   AHy.
CA   Acetaldehyde = acetylene + H(2)O.
CF   Bis(molybdopterin guanine dinucleotide)molybdenum cofactor; Iron-sulfur;
CF   Tungsten.
CC   -!- The tungsten center binds a water molecule that is activated by an
CC       adjacent aspartate residue, enabling it to attack acetylene bound in
CC       a distinct hydrophobic pocket.
CC   -!- Ethylene cannot act as a substrate.
//
ID   4.2.1.113
DE   o-succinylbenzoate synthase.
AN   2-succinylbenzoate synthase.
AN   o-succinylbenzoic acid synthase.
AN   OSB synthase.
AN   OSBS.
CA   (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate =
CA   2-succinylbenzoate + H(2)O.
CF   Manganese or magnesium.
CC   -!- Forms part of the vitamin-K biosynthesis pathway.
DR   B6EJ59, MENC_ALISL ;  O34514, MENC_BACSU ;  A8ADX2, MENC_CITK8 ;
DR   A7ZP80, MENC_ECO24 ;  B7UFS4, MENC_ECO27 ;  B7MG29, MENC_ECO45 ;
DR   B7LAS7, MENC_ECO55 ;  P58484, MENC_ECO57 ;  B5YXQ5, MENC_ECO5E ;
DR   B7NNU1, MENC_ECO7I ;  B7MXE4, MENC_ECO81 ;  B7M5U4, MENC_ECO8A ;
DR   C4ZUA4, MENC_ECOBW ;  B1X8X5, MENC_ECODH ;  A8A2C9, MENC_ECOHS ;
DR   A1ADB3, MENC_ECOK1 ;  Q0TFI0, MENC_ECOL5 ;  Q8FFL4, MENC_ECOL6 ;
DR   B1IXS5, MENC_ECOLC ;  P29208, MENC_ECOLI ;  B7N5M7, MENC_ECOLU ;
DR   B6I7K5, MENC_ECOSE ;  B1LLL6, MENC_ECOSM ;  Q1R9F3, MENC_ECOUT ;
DR   C5B7H9, MENC_EDWI9 ;  A4WCP6, MENC_ENT38 ;  Q6D7W1, MENC_ERWCT ;
DR   B7LM69, MENC_ESCF3 ;  P44961, MENC_HAEIN ;  B5XNX3, MENC_KLEP3 ;
DR   A6TBV5, MENC_KLEP7 ;  P65426, MENC_MYCBO ;  A1KG30, MENC_MYCBP ;
DR   C1AKN3, MENC_MYCBT ;  Q9CBB2, MENC_MYCLE ;  B2HRP4, MENC_MYCMM ;
DR   A0QRG0, MENC_MYCS2 ;  A5TZT3, MENC_MYCTA ;  P65425, MENC_MYCTU ;
DR   A0PLU7, MENC_MYCUA ;  Q9CLV7, MENC_PASMU ;  C6DBP5, MENC_PECCP ;
DR   Q7N2K6, MENC_PHOLL ;  B4EZ39, MENC_PROMH ;  B5EZI5, MENC_SALA4 ;
DR   A9MJB9, MENC_SALAR ;  Q57M50, MENC_SALCH ;  B5FPE5, MENC_SALDC ;
DR   B5R2Y7, MENC_SALEP ;  B5RCD1, MENC_SALG2 ;  B4TBH3, MENC_SALHS ;
DR   B4SYX8, MENC_SALNS ;  Q5PN73, MENC_SALPA ;  A9N5A5, MENC_SALPB ;
DR   C0Q062, MENC_SALPC ;  B5BCN9, MENC_SALPK ;  B4TPI9, MENC_SALSV ;
DR   P58485, MENC_SALTI ;  P58486, MENC_SALTY ;  B2TW47, MENC_SHIB3 ;
DR   Q31YJ6, MENC_SHIBS ;  Q32DS7, MENC_SHIDS ;  Q83QT6, MENC_SHIFL ;
DR   Q3YZU5, MENC_SHISS ;  Q55117, MENC_SYNY3 ;  Q9KQM6, MENC_VIBCH ;
DR   C3LNS3, MENC_VIBCM ;  Q5E484, MENC_VIBF1 ;  B5FFK8, MENC_VIBFM ;
DR   A1JKU9, MENC_YERE8 ;  A7FGT5, MENC_YERP3 ;  Q1C6E0, MENC_YERPA ;
DR   B2K7Z0, MENC_YERPB ;  P58487, MENC_YERPE ;  A9R6I7, MENC_YERPG ;
DR   Q1CHT2, MENC_YERPN ;  A4TM05, MENC_YERPP ;  Q669D0, MENC_YERPS ;
DR   B1JH91, MENC_YERPY ;  Q15KI9, PHYLO_ARATH;
//
ID   4.2.1.114
DE   Methanogen homoaconitase.
AN   Methanogen HACN.
CA   (R)-2-hydroxybutane-1,2,4-tricarboxylate = (1R,2S)-1-hydroxybutane-1,2,4-
CA   tricarboxylate.
CF   Iron-sulfur.
CC   -!- Catalyzes several reactions in the pathway of coenzyme-B biosynthesis
CC       in methanogenic archaea.
CC   -!- In contrast to EC 4.2.1.36, this enzyme can catalyze both the
CC       dehydration of (R)-homocitrate to form cis-homoaconitate and the
CC       subsequent hydration reaction that forms homoisocitrate.
CC   -!- In addition to cis-homoaconitate, the enzyme can also catalyze the
CC       hydration of the physiological substrates dihomocitrate and
CC       trihomocitrate as well as the non-physiological substrate
CC       tetrahomocitrate.
CC   -!- Cis-aconitate and threo-DL-isocitrate cannot act as substrates,
CC       and (S)-homocitrate and trans-homoaconitate act as inhibitors of the
CC       enzyme.
PR   PROSITE; PDOC00423;
//
ID   4.2.1.115
DE   UDP-N-acetylglucosamine 4,6-dehydratase (inverting).
CA   UDP-N-acetylglucosamine = UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-
CA   hex-4-ulose + H(2)O.
CF   NADPH.
CC   -!- The first enzyme in the biosynthetic pathway of pseudaminic acid,
CC       a sialic-acid-like sugar that is unique to bacteria and is used by
CC       Helicobacter pylori to modify its flagellin.
CC   -!- Plays a critical role in H.pylori's pathogenesis, being involved in
CC       the synthesis of both functional flagella and lipopolysaccharides.
CC   -!- Completely inhibited by UDP-galactose.
CC   -!- The reaction results in the chirality of the C-5 atom being inverted.
CC   -!- It is thought that Lys-133 acts sequentially as a catalytic acid,
CC       protonating the C-6 hydroxy group and as a catalytic base,
CC       abstracting the C-5 proton, resulting in the elimination of water.
//
ID   4.2.1.116
DE   3-hydroxypropionyl-CoA dehydratase.
CA   3-hydroxypropanoyl-CoA = acrylyl-CoA + H(2)O.
CC   -!- Catalyzes a step in the 3-hydroxypropanoate/4-hydroxybutyrate cycle,
CC       an autotrophic CO(2) fixation pathway found in some thermoacidophilic
CC       archaea.
CC   -!- The enzyme from Metallosphaera sedula acts nearly equally as well on
CC       (S)-3-hydroxybutanoyl-CoA but not (R)-3-hydroxybutanoyl-CoA.
PR   PROSITE; PDOC00150;
DR   A4YI89, HPCD_METS5 ;
//
ID   4.2.1.117
DE   2-methylcitrate dehydratase (2-methyl-trans-aconitate forming).
CA   (2S,3S)-2-methylcitrate = 2-methyl-trans-aconitate + H(2)O.
CF   Iron-sulfur.
CC   -!- Catalyzes the dehydration of (2S,3S)-2-methylcitrate, forming the
CC       trans isomer of 2-methyl-aconitate (unlike EC 4.2.1.79, which forms
CC       only the cis isomer).
CC   -!- Part of a propanoate degradation pathway.
CC   -!- The enzyme from Shewanella oneidensis can also accept citrate and
CC       cis-aconitate, but activity with (2S,3S)-2-methylcitrate was
CC       approximately 2.5-fold higher.
CC   -!- 2-methylisocitrate and isocitrate were not substrates.
//
ID   4.2.1.118
DE   3-dehydroshikimate dehydratase.
CA   3-dehydro-shikimate = protocatechuate + H(2)O.
CF   Manganese.
CC   -!- Catalyzes an early step in the biosynthesis of petrobactin,
CC       a siderophore produced by many bacteria, including the human pathogen
CC       Bacillus anthracis.
DR   Q81RQ4, ASBF_BACAN ;  Q43922, QUIC_ACIAD ;
//
ID   4.2.1.119
DE   Enoyl-CoA hydratase 2.
AN   2-enoyl-CoA hydratase 2.
AN   D-3-hydroxyacyl-CoA hydro-lyase.
AN   D-specific 2-trans-enoyl-CoA hydratase.
AN   ECH2.
CA   (3R)-3-hydroxyacyl-CoA = (2E)-2-enoyl-CoA + H(2)O.
CC   -!- This enzyme catalyzes a hydration step in peroxisomal beta-oxidation.
CC   -!- The human multifunctional enzyme type 2 (MFE-2) is a 79000 Da enzyme
CC       composed of three functional units: (3R)-hydroxyacyl-CoA
CC       dehydrogenase, 2-enoyl-CoA hydratase 2 and sterol carrier protein
CC       2-like units.
CC   -!- The enzymes from Aeromonas caviae and Arabidopsis thaliana are
CC       monofunctional enzymes.
CC   -!- 2-Enoyl-CoA hydratase 3 from Candida tropicalis is a part from
CC       multifunctional enzyme type 2.
DR   P51659, DHB4_HUMAN ;  P51660, DHB4_MOUSE ;  P97852, DHB4_RAT   ;
DR   Q8VYI3, ECH2_ARATH ;  P22414, FOX2_CANTR ;  Q01373, FOX2_NEUCR ;
DR   Q02207, FOX2_YEAST ;  Q54XZ0, MFEB_DICDI ;
//
ID   4.2.1.120
DE   4-hydroxybutanoyl-CoA dehydratase.
CA   4-hydroxybutanoyl-CoA = but-3-enoyl-CoA + H(2)O.
CF   Iron-sulfur and FAD.
CC   -!- The enzyme is often present as a bifunctional enzyme, catalyzing the
CC       dehydration of 4-hydroxybutanoyl-CoA to but-3-enoyl-CoA followed by
CC       isomerization of the later to crotonyl-CoA (EC 5.3.3.3).
CC   -!- The enzyme has been characterized from several microorganisms,
CC       including Clostridium kluyveri, where it participates in succinate
CC       fermentation, Clostridium aminobutyricum, where it participates in
CC       4-aminobutyrate degradation, and Metallosphaera sedula, where it
CC       participates in the 3-hydroxypropanoate/4-hydroxybutyrate cycle,
CC       an autotrophic CO(2) fixation pathway found in some thermoacidophilic
CC       archaea.
DR   P55792, HDVD_CLOAM ;
//
ID   4.2.1.121
DE   Colneleate synthase.
AN   9-DES.
AN   9-divinyl ether synthase.
CA   (9S,10E,12Z)-9-hydroperoxyoctadeca-10,12-dienoate = (8E)-9-((1E,3Z)-nona-
CA   1,3-dien-1-yloxy)non-8-enoate + H(2)O.
CF   Heme-thiolate.
CC   -!- It catalyzes the selective removal of pro-R hydrogen at C-8 in the
CC       biosynthesis of colneleic acid.
CC   -!- It forms also (8E)-9-((1E,3Z,6Z)-nona-1,3,6-trien-1-yloxy)non-8-enoic
CC       acid (i.e. colnelenate) from (9Z,10E,12Z,15Z)-9-hydroperoxy-10,12,15-
CC       octadecatrienoate.
CC   -!- The corresponding 13-hydroperoxides are poor substrates.
CC   -!- The divinyl ethers colneleate and colnelenate have antimicrobial
CC       activity.
//
ID   4.2.1.122
DE   Tryptophan synthase (indole-salvaging).
AN   Tryptophan synthase beta-2.
CA   L-serine + indole = L-tryptophan + H(2)O.
CC   -!- Most mesophilic bacteria have a multimeric tryptophan synthase
CC       complex (EC 4.2.1.20) that forms L-tryptophan from L-serine and 1-C-
CC       (indol-3-yl)glycerol 3-phosphate via an indole intermediate.
CC   -!- This intermediate, which is formed by the alpha subunits,
CC       is transferred in an internal tunnel to the beta units, which convert
CC       it to tryptophan.
CC   -!- In thermophilic organisms the high temperature enhances diffusion and
CC       causes the loss of indole.
CC   -!- This enzyme, which does not combine with the alpha unit to form a
CC       complex, salvages the lost indole back to L-tryptophan.
CC   -!- It has a much lower Km for indole than the beta subunit of
CC       EC 4.2.1.20.
//
ID   4.2.1.123
DE   Tetrahymanol synthase.
AN   Squalene--tetrahymanol cyclase.
CA   Tetrahymanol = squalene + H(2)O.
CC   -!- The reaction occurs in the reverse direction.
//
ID   4.2.1.124
DE   Arabidiol synthase.
CA   Arabidiol = (S)-squalene-2,3-epoxide + H(2)O.
CC   -!- The reaction occurs in the reverse direction.
DR   Q9FR95, PEN1_ARATH ;
//
ID   4.2.1.125
DE   Dammarenediol II synthase.
AN   2,3-oxidosqualene (20S)-dammarenediol cyclase.
AN   Dammarenediol synthase.
CA   Dammarenediol II = (S)-squalene-2,3-epoxide + H(2)O.
CC   -!- The reaction occurs in the reverse direction.
DR   Q08IT1, DADIS_PANGI;
//
ID   4.2.1.126
DE   N-acetylmuramic acid 6-phosphate etherase.
AN   MurNAc-6-P etherase.
CA   N-acetylmuramate 6-phosphate + H(2)O = N-acetyl-D-glucosamine 6-phosphate
CA   + D-lactate.
CC   -!- This enzyme, along with EC 2.7.1.170, is required for the utilization
CC       of anhydro-N-acetylmuramic acid in proteobacteria.
CC   -!- The substrate is either imported from the medium or derived from the
CC       bacterium's own cell wall murein during cell wall recycling.
CC   -!- Formerly EC 4.2.1.n1.
DR   Q65P54, MURQ1_BACLD;  Q838I8, MURQ1_ENTFA;  Q88SC3, MURQ1_LACPL;
DR   Q9KVE0, MURQ1_VIBCH;  Q87S81, MURQ1_VIBPA;  Q65CQ5, MURQ2_BACLD;
DR   Q831R4, MURQ2_ENTFA;  Q88SB0, MURQ2_LACPL;  Q9KU39, MURQ2_VIBCH;
DR   Q87FD6, MURQ2_VIBPA;  A3N2I4, MURQ_ACTP2 ;  B3GYL8, MURQ_ACTP7 ;
DR   B0BRD0, MURQ_ACTPJ ;  A6VKY9, MURQ_ACTSZ ;  A0KFC0, MURQ_AERHH ;
DR   B9JJJ9, MURQ_AGRRK ;  B6EJZ8, MURQ_ALISL ;  A6TVQ2, MURQ_ALKMQ ;
DR   Q3MGL8, MURQ_ANAVT ;  A7Z0U6, MURQ_BACA2 ;  C3P1J8, MURQ_BACAA ;
DR   C3LE93, MURQ_BACAC ;  Q81UP1, MURQ_BACAN ;  B7JSA1, MURQ_BACC0 ;
DR   Q73D01, MURQ_BACC1 ;  B7II82, MURQ_BACC2 ;  C1EYT0, MURQ_BACC3 ;
DR   B7HER4, MURQ_BACC4 ;  B7HXH0, MURQ_BACC7 ;  A7GLK9, MURQ_BACCN ;
DR   B9IR64, MURQ_BACCQ ;  Q81HH1, MURQ_BACCR ;  Q63FJ0, MURQ_BACCZ ;
DR   Q5LI89, MURQ_BACFN ;  Q64ZA1, MURQ_BACFR ;  Q9K6Z9, MURQ_BACHD ;
DR   Q6HMZ5, MURQ_BACHK ;  A8F9E0, MURQ_BACP2 ;  Q5WLA2, MURQ_BACSK ;
DR   Q45582, MURQ_BACSU ;  Q8ABH7, MURQ_BACTN ;  A9VGE7, MURQ_BACWK ;
DR   Q39MM8, MURQ_BURS3 ;  Q97MM1, MURQ_CLOAB ;  A7FTM1, MURQ_CLOB1 ;
DR   C3KUL4, MURQ_CLOB6 ;  A6LUQ7, MURQ_CLOB8 ;  B2TPW8, MURQ_CLOBB ;
DR   A5I1H8, MURQ_CLOBH ;  C1FLJ7, MURQ_CLOBJ ;  B1IK79, MURQ_CLOBK ;
DR   A7GD48, MURQ_CLOBL ;  B1L0G9, MURQ_CLOBM ;  Q184N3, MURQ_CLOD6 ;
DR   Q480D3, MURQ_COLP3 ;  B1WPP6, MURQ_CYAA5 ;  B7KFK5, MURQ_CYAP7 ;
DR   B7JYZ1, MURQ_CYAP8 ;  Q1J3J3, MURQ_DEIGD ;  Q9RYU5, MURQ_DEIRA ;
DR   A7ZPM8, MURQ_ECO24 ;  B7UGC8, MURQ_ECO27 ;  B7MHT0, MURQ_ECO45 ;
DR   B7LCH2, MURQ_ECO55 ;  Q8XBJ2, MURQ_ECO57 ;  B5YZX3, MURQ_ECO5E ;
DR   B7NPW4, MURQ_ECO7I ;  B7MY79, MURQ_ECO81 ;  B7M6T7, MURQ_ECO8A ;
DR   C4ZVV9, MURQ_ECOBW ;  B1XA99, MURQ_ECODH ;  A8A2S5, MURQ_ECOHS ;
DR   A1ADU3, MURQ_ECOK1 ;  Q0TF40, MURQ_ECOL5 ;  Q8FFB0, MURQ_ECOL6 ;
DR   B1IX44, MURQ_ECOLC ;  P76535, MURQ_ECOLI ;  B7N618, MURQ_ECOLU ;
DR   B6I504, MURQ_ECOSE ;  B1LMM2, MURQ_ECOSM ;  Q1R8U4, MURQ_ECOUT ;
DR   C5BBH3, MURQ_EDWI9 ;  A4WDD1, MURQ_ENT38 ;  Q8GC81, MURQ_ENTAE ;
DR   A7MGZ1, MURQ_ENTS8 ;  Q6D234, MURQ_ERWCT ;  B2VEB1, MURQ_ERWT9 ;
DR   B7LKK7, MURQ_ESCF3 ;  C4KZ07, MURQ_EXISA ;  B0TXA4, MURQ_FRAP2 ;
DR   Q2A5B0, MURQ_FRATH ;  A0Q804, MURQ_FRATN ;  Q5NEW3, MURQ_FRATT ;
DR   C5DAG6, MURQ_GEOSW ;  A4IPI2, MURQ_GEOTN ;  Q7NE68, MURQ_GLOVI ;
DR   A0M6M4, MURQ_GRAFK ;  P44862, MURQ_HAEIN ;  B8F4V1, MURQ_HAEPS ;
DR   Q0I1F8, MURQ_HAES1 ;  B0UW11, MURQ_HAES2 ;  Q28KP2, MURQ_JANSC ;
DR   Q5FIF8, MURQ_LACAC ;  Q03QK0, MURQ_LACBA ;  Q040J1, MURQ_LACGA ;
DR   Q74HC8, MURQ_LACJO ;  Q9CGG6, MURQ_LACLA ;  A2RL43, MURQ_LACLM ;
DR   Q02Z51, MURQ_LACLS ;  C1KVV7, MURQ_LISMC ;  Q71Z09, MURQ_LISMF ;
DR   A0AJB3, MURQ_LISW6 ;  Q65R16, MURQ_MANSM ;  B0JQG3, MURQ_MICAN ;
DR   Q6MTZ7, MURQ_MYCMS ;  A0QNX1, MURQ_MYCS2 ;  B2IU18, MURQ_NOSP7 ;
DR   Q8YUC0, MURQ_NOSS1 ;  Q8ESL3, MURQ_OCEIH ;  A6X3M9, MURQ_OCHA4 ;
DR   Q04HN0, MURQ_OENOB ;  P57951, MURQ_PASMU ;  A9BFQ1, MURQ_PETMO ;
DR   Q7N9D8, MURQ_PHOLL ;  Q6LL16, MURQ_PHOPR ;  B2RK20, MURQ_PORG3 ;
DR   Q7MVG5, MURQ_PORGI ;  Q6A8M7, MURQ_PROAC ;  A2C236, MURQ_PROM1 ;
DR   A2C9U9, MURQ_PROM3 ;  Q7VC01, MURQ_PROMA ;  Q7V7N4, MURQ_PROMM ;
DR   Q46L21, MURQ_PROMT ;  Q15N71, MURQ_PSEA6 ;  A1STT9, MURQ_PSYIN ;
DR   Q986Q8, MURQ_RHILO ;  Q7UNL6, MURQ_RHOBA ;  Q1AYD7, MURQ_RUBXD ;
DR   B5F1F1, MURQ_SALA4 ;  Q57LE0, MURQ_SALCH ;  B5FRB5, MURQ_SALDC ;
DR   B5QTT8, MURQ_SALEP ;  B5RD39, MURQ_SALG2 ;  B4TDE5, MURQ_SALHS ;
DR   B4T1E8, MURQ_SALNS ;  Q5PII8, MURQ_SALPA ;  A9N1U1, MURQ_SALPB ;
DR   B5BAU0, MURQ_SALPK ;  Q2S6G3, MURQ_SALRD ;  B4TS04, MURQ_SALSV ;
DR   Q8Z4L2, MURQ_SALTI ;  Q8ZN25, MURQ_SALTY ;  A8GI17, MURQ_SERP5 ;
DR   B2TX17, MURQ_SHIB3 ;  Q31Y51, MURQ_SHIBS ;  Q32DC6, MURQ_SHIDS ;
DR   Q0T280, MURQ_SHIF8 ;  Q83QN4, MURQ_SHIFL ;  Q3YZB4, MURQ_SHISS ;
DR   Q2FK71, MURQ_STAA3 ;  Q2G1G6, MURQ_STAA8 ;  Q2YUY9, MURQ_STAAB ;
DR   Q5HJI1, MURQ_STAAC ;  Q99X30, MURQ_STAAM ;  Q7A805, MURQ_STAAN ;
DR   Q6GKB5, MURQ_STAAR ;  Q6GCT5, MURQ_STAAS ;  Q7A1Y2, MURQ_STAAW ;
DR   Q5HLT3, MURQ_STAEQ ;  Q8CRD9, MURQ_STAES ;  Q4L8H4, MURQ_STAHJ ;
DR   Q49ZN6, MURQ_STAS1 ;  Q82GH3, MURQ_STRAW ;  Q9KXT4, MURQ_STRCO ;
DR   Q67RV4, MURQ_SYMTH ;  O33701, MURQ_SYNE7 ;  Q2JMP1, MURQ_SYNJB ;
DR   B1XMC7, MURQ_SYNP2 ;  Q5N1U7, MURQ_SYNP6 ;  Q7U6S0, MURQ_SYNPX ;
DR   Q3AXW8, MURQ_SYNS9 ;  Q3AJT5, MURQ_SYNSC ;  P73585, MURQ_SYNY3 ;
DR   Q8DJQ1, MURQ_THEEB ;  Q47U25, MURQ_THEFY ;  A8F7W0, MURQ_THELT ;
DR   B0K1N2, MURQ_THEPX ;  Q8RD35, MURQ_THETN ;  Q119L1, MURQ_TRIEI ;
DR   Q5E5T7, MURQ_VIBF1 ;  B5FDJ8, MURQ_VIBFM ;  A7MTC9, MURQ_VIBHB ;
DR   B7VJM5, MURQ_VIBSL ;  Q8D4Z4, MURQ_VIBVU ;  Q7MBS3, MURQ_VIBVY ;
DR   A7FFU6, MURQ_YERP3 ;  Q1C5E3, MURQ_YERPA ;  B2KA40, MURQ_YERPB ;
DR   Q8ZCP8, MURQ_YERPE ;  A9R410, MURQ_YERPG ;  Q1CKD6, MURQ_YERPN ;
DR   A4TMY1, MURQ_YERPP ;  Q667V7, MURQ_YERPS ;  B1JRW1, MURQ_YERPY ;
//
ID   4.2.1.n1
DE   Transferred entry: 4.2.1.126.
//
ID   4.2.2.1
DE   Hyaluronate lyase.
AN   Hyaluronidase.
AN   Mucinase.
AN   Spreading factor.
CA   Cleaves hyaluronate chains at a beta-D-GalNAc-(1->4)-beta-D-GlcA bond,
CA   ultimately breaking the polysaccharide down to 3-(4-deoxy-beta-D-gluc-4-
CA   enuronosyl)-N-acetyl-D-glucosamine.
CC   -!- Also acts on chondroitin.
CC   -!- The product is more systematically known as 3-(4-deoxy-alpha-L-threo-
CC       hex-4-enopyranosyluronic acid)-2-acetamido-2-deoxy-D-glucose.
CC   -!- Formerly EC 4.2.99.1.
DR   P0CZ00, HYSA_PROAA ;  P0CZ01, HYSA_PROAC ;  Q59801, HYSA_STAA8 ;
DR   Q53591, HYSA_STRA3 ;  Q54873, HYSA_STRPN ;
//
ID   4.2.2.2
DE   Pectate lyase.
AN   Alpha-1,4-D-endopolygalacturonic acid lyase.
AN   Endo-alpha-1,4-polygalacturonic acid lyase.
AN   Endogalacturonate transeliminase.
AN   Endopectin methyltranseliminase.
AN   Pectate transeliminase.
AN   Pectic acid lyase.
AN   Pectic acid transeliminase.
AN   Pectic lyase.
AN   Pectin trans-eliminase.
AN   PGA lyase.
AN   Polygalacturonate lyase.
AN   Polygalacturonic acid lyase.
AN   Polygalacturonic acid trans-eliminase.
AN   Polygalacturonic transeliminase.
AN   PPase-N.
CA   Eliminative cleavage of (1->4)-alpha-D-galacturonan to give
CA   oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their
CA   non-reducing ends.
CC   -!- Favors pectate, the anion, over pectin, the methyl ester (which is
CC       the preferred substrate of EC 4.2.2.10).
CC   -!- Formerly EC 4.2.99.3.
DR   Q9LJ42, PLY10_ARATH;  Q9LTZ0, PLY11_ARATH;  Q9SCP2, PLY12_ARATH;
DR   Q93Z04, PLY13_ARATH;  Q9SVQ6, PLY14_ARATH;  Q944R1, PLY15_ARATH;
DR   O65456, PLY16_ARATH;  O65457, PLY17_ARATH;  Q9C5M8, PLY18_ARATH;
DR   P24396, PLY18_SOLLC;  Q9LFP5, PLY19_ARATH;  Q940Q1, PLY1_ARATH ;
DR   P0C1C0, PLY1_ERWCA ;  Q6CZT4, PLY1_ERWCT ;  Q93WF1, PLY20_ARATH;
DR   Q9FM66, PLY21_ARATH;  Q93Z25, PLY22_ARATH;  O65388, PLY2_ARATH ;
DR   P0C1C1, PLY2_ERWCA ;  Q6CZT3, PLY2_ERWCT ;  Q9M9S2, PLY3_ARATH ;
DR   P0C1C2, PLY3_ERWCA ;  Q6CZT2, PLY3_ERWCT ;  P0C1C3, PLY3_PECCC ;
DR   Q9C8G4, PLY4_ARATH ;  P15721, PLY56_SOLLC;  P15722, PLY59_SOLLC;
DR   Q9FXD8, PLY5_ARATH ;  O64510, PLY6_ARATH ;  Q9SRH4, PLY7_ARATH ;
DR   Q9M8Z8, PLY8_ARATH ;  Q9LRM5, PLY9_ARATH ;  B0XT32, PLYA_ASPFC ;
DR   B8NE46, PLYA_ASPFN ;  Q4WIT0, PLYA_ASPFU ;  A2QV36, PLYA_ASPNC ;
DR   Q9C2Z0, PLYA_ASPNG ;  Q2U8R6, PLYA_ASPOR ;  P0C1A3, PLYA_DICD3 ;
DR   Q5AVN4, PLYA_EMENI ;  P0C1A2, PLYA_ERWCH ;  A1CYB8, PLYA_NEOFI ;
DR   Q9X6Z2, PLYA_PAEBA ;  B8NBC2, PLYB_ASPFN ;  Q2TZY0, PLYB_ASPOR ;
DR   Q0CBV0, PLYB_ASPTN ;  O59939, PLYB_COLGL ;  Q00645, PLYB_EMENI ;
DR   P04959, PLYB_ERWCH ;  B0XMA2, PLYC_ASPFC ;  B8NQQ7, PLYC_ASPFN ;
DR   Q4WL88, PLYC_ASPFU ;  Q2UB83, PLYC_ASPOR ;  Q0CLG7, PLYC_ASPTN ;
DR   Q65EF5, PLYC_BACLD ;  O34310, PLYC_BACSU ;  Q5B297, PLYC_EMENI ;
DR   P11073, PLYC_ERWCH ;  A1DPF0, PLYC_NEOFI ;  B0YB89, PLYD_ASPFC ;
DR   Q4WGV9, PLYD_ASPFU ;  Q0CJ49, PLYD_ASPTN ;  Q5BA88, PLYD_EMENI ;
DR   P18209, PLYD_ERWCH ;  A1DCY5, PLYD_NEOFI ;  P04960, PLYE1_ERWCH;
DR   P0C1A4, PLYE2_ERWCH;  A1C4B8, PLYE_ASPCL ;  B0Y9M8, PLYE_ASPFC ;
DR   B8NX10, PLYE_ASPFN ;  Q4WC29, PLYE_ASPFU ;  Q2TW49, PLYE_ASPOR ;
DR   P0C1A5, PLYE_DICD3 ;  Q5B7Z3, PLYE_EMENI ;  A1DBJ7, PLYE_NEOFI ;
DR   B0Y953, PLYF_ASPFC ;  B8NJZ7, PLYF_ASPFN ;  Q4WKV8, PLYF_ASPFU ;
DR   Q0CCF8, PLYF_ASPTN ;  Q5B024, PLYF_EMENI ;  A1D5E3, PLYF_NEOFI ;
DR   Q0CJ20, PLYG_ASPTN ;  Q5AY82, PLYG_EMENI ;  Q5ATC7, PLYH_EMENI ;
DR   P0C1A7, PLYL_DICD3 ;  P0C1A6, PLYL_ERWCH ;  P14005, PLYP_PECCC ;
DR   P11278, PLYP_YERPS ;  P16530, PLYX_ERWCA ;  P39116, PLY_BACSU  ;
DR   P40973, PLY_LILLO  ;  Q59671, PLY_PSEFL  ;  Q51915, PLY_PSEMA  ;
DR   P72242, PLY_PSESL  ;  Q60140, PLY_PSEVI  ;  P40972, PLY_TOBAC  ;
DR   Q56806, PLY_XANCM  ;  O24554, PLY_ZINEL  ;
//
ID   4.2.2.3
DE   Poly(beta-D-mannuronate) lyase.
AN   Alginate lyase I.
AN   Poly(mana) alginate lyase.
CA   Eliminative cleavage of polysaccharides containing beta-D-mannuronate
CA   residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-
CA   enopyranuronosyl groups at their ends.
CC   -!- Formerly EC 4.2.99.4.
DR   O50660, ALGL_AZOCH ;  C1DP89, ALGL_AZOVD ;  O52195, ALGL_AZOVI ;
DR   Q9ZNB7, ALGL_HALMR ;  A6V1P7, ALGL_PSEA7 ;  B7UUU9, ALGL_PSEA8 ;
DR   Q02R18, ALGL_PSEAB ;  Q06749, ALGL_PSEAE ;  Q1I563, ALGL_PSEE4 ;
DR   Q4KHY5, ALGL_PSEF5 ;  P59786, ALGL_PSEFL ;  C3KDZ3, ALGL_PSEFS ;
DR   A5W8V4, ALGL_PSEP1 ;  Q3KHR0, ALGL_PSEPF ;  B0KGQ9, ALGL_PSEPG ;
DR   Q88ND1, ALGL_PSEPK ;  B1J479, ALGL_PSEPW ;  Q887Q5, ALGL_PSESM ;
DR   Q9L7P2, ALGL_PSESY ;  Q4ZXL0, ALGL_PSEU2 ;  P39049, ALXM_PHOS4 ;
DR   Q59478, ALYA_KLEPN ;  Q59639, ALYA_PSEAL ;  Q06365, ALYP_PSESO ;
//
ID   4.2.2.4
DE   Transferred entry: 4.2.2.20 and 4.2.2.21.
//
ID   4.2.2.5
DE   Chondroitin AC lyase.
AN   Chondroitin AC eliminase.
AN   Chondroitin sulfate lyase.
AN   Chondroitinase.
CA   Eliminative degradation of polysaccharides containing 1,4-beta-D-
CA   hexosaminyl and 1,3-beta-D-glucuronosyl linkages to disaccharides
CA   containing 4-deoxy-beta-D-gluc-4-enuronosyl groups.
CC   -!- Acts on chondroitin 4-sulfate and chondroitin 6-sulfate, but less
CC       well on hyaluronate.
CC   -!- In general, chondroitin sulfate (CS) and dermatan sulfate (DS) chains
CC       comprise a linkage region, a chain cap and a repeat region.
CC   -!- The repeat region of CS is a repeating disaccharide of glucuronic
CC       acid (GlcA) and N-acetylgalactosamine (GalNAc) [-4)GlcA(beta-1-
CC       3)GalNAc(beta-1-](n), which may be O-sulfated on the C-4 and/or C-6
CC       of GalNAc and C-2 of GlcA.
CC   -!- GlcA residues of CS may be epimerized to iduronic acid (IdoA) forming
CC       the repeating disaccharide [-4)IdoA(alpha-1-3)GalNAc(beta-1-](n) of
CC       DS.
CC   -!- Both the concentrations and locations of sulfate-ester substituents
CC       vary with glucosaminoglycan source.
CC   -!- Formerly EC 4.2.99.6.
DR   Q59288, CSLA_PEDHD ;
//
ID   4.2.2.6
DE   Oligogalacturonide lyase.
CA   4-(4-deoxy-beta-D-galact-4-enuronosyl)-D-galacturonate = 2 5-dehydro-4-
CA   deoxy-D-glucuronate.
CC   -!- Also catalyzes eliminative removal of unsaturated terminal residues
CC       from oligosaccharides of D-galacturonate.
DR   P21258, OGL_DICD3  ;  Q59418, OGL_ERWCT  ;
//
ID   4.2.2.7
DE   Heparin lyase.
AN   Heparin eliminase.
AN   Heparinase.
CA   Eliminative cleavage of polysaccharides containing (1->4)-linked
CA   D-glucuronate or L-iduronate residues and (1->4)-alpha-linked
CA   2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides
CA   with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-
CA   reducing ends.
DR   P83054, HEP1_BACSE ;  Q05819, HEP1_PEDHE ;
//
ID   4.2.2.8
DE   Heparin-sulfate lyase.
AN   Heparin-sulfate eliminase.
AN   Heparitin-sulfate lyase.
CA   Elimination of sulfate; appears to act on linkages between N-acetyl-D-
CA   glucosamine and uronate. Product is an unsaturated sugar.
CC   -!- Does not act on N,O-desulfated glucosamine or N-acetyl-O-sulfated
CC       glucosamine linkages.
//
ID   4.2.2.9
DE   Pectate disaccharide-lyase.
AN   Exo-PATE.
AN   Exo-PGL.
AN   Exopectate lyase.
AN   Exopectic acid transeliminase.
AN   Exopolygalacturonate lyase.
AN   Exopolygalacturonic acid-trans-eliminase.
AN   PATE.
AN   Pectate exo-lyase.
CA   Eliminative cleavage of 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-
CA   galacturonate from the reducing end of pectate, i.e. de-esterified
CA   pectin.
DR   Q05526, PLYW_DICD3 ;  P22751, PLYX_ERWCH ;
//
ID   4.2.2.10
DE   Pectin lyase.
AN   Endo-pectin lyase.
AN   Pectin methyltranseliminase.
AN   Pectin trans-eliminase.
AN   Pectolyase.
AN   PL.
AN   PMGL.
AN   PNL.
AN   Polymethylgalacturonic transeliminase.
CA   Eliminative cleavage of (1->4)-alpha-D-galacturonan methyl ester to give
CA   oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl
CA   groups at their non-reducing ends.
CC   -!- Favors pectin, the methyl ester, over pectate, the anion (which is
CC       the preferred substrate of EC 4.2.2.2).
DR   O34819, PEL1_BACSU ;  P94449, PEL2_BACSU ;  A1CFS2, PELA_ASPCL ;
DR   B0XT36, PELA_ASPFC ;  B8N6W5, PELA_ASPFN ;  Q4WV10, PELA_ASPFU ;
DR   A2R3I1, PELA_ASPNC ;  Q01172, PELA_ASPNG ;  Q2TXM4, PELA_ASPOR ;
DR   Q0CYL8, PELA_ASPTN ;  Q00374, PELA_COLGL ;  Q5BAU9, PELA_EMENI ;
DR   Q12639, PELA_MYCPO ;  A1CYC2, PELA_NEOFI ;  B0YCL3, PELB_ASPFC ;
DR   Q4WIS6, PELB_ASPFU ;  A2QFN7, PELB_ASPNC ;  Q00205, PELB_ASPNG ;
DR   Q2TWM1, PELB_ASPOR ;  Q5BA61, PELB_EMENI ;  A2QW65, PELC_ASPNC ;
DR   Q5MBK3, PELC_ASPNG ;  Q2UCT7, PELC_ASPOR ;  Q5BEB9, PELC_EMENI ;
DR   B8NVB7, PELD_ASPFN ;  A2RBL2, PELD_ASPNC ;  P22864, PELD_ASPNG ;
DR   Q2TXS4, PELD_ASPOR ;  Q5AQJ1, PELD_EMENI ;  P24112, PELD_ERWCA ;
DR   P27027, PELD_PSEMA ;  B3GQR3, PELE_ASPNG ;  Q0CFF7, PELF1_ASPTN;
DR   Q0CZD4, PELF2_ASPTN;  B0Y0L8, PELF_ASPFC ;  B8N316, PELF_ASPFN ;
DR   A2R6A1, PELF_ASPNC ;  Q8NJK6, PELF_ASPNG ;  Q2UJA7, PELF_ASPOR ;
DR   Q5B3J8, PELF_EMENI ;  A1DEH0, PELF_NEOFI ;  Q9X6Z2, PLYA_PAEBA ;
DR   Q65EF5, PLYC_BACLD ;  O34310, PLYC_BACSU ;
//
ID   4.2.2.11
DE   Poly(alpha-L-guluronate) lyase.
AN   Alginase II.
CA   Eliminative cleavage of polysaccharides containing a terminal alpha-L-
CA   guluronate group, to give oligosaccharides with 4-deoxy-alpha-L-erythro-
CA   hex-4-enuronosyl groups at their non-reducing ends.
//
ID   4.2.2.12
DE   Xanthan lyase.
CA   Eliminative cleavage of the terminal beta-D-mannosyl-(1->4)-beta-D-
CA   glucuronosyl linkage of the side-chain of the polysaccharide xanthan,
CA   leaving a 4-deoxy-alpha-L-threo-hex-4-enuronosyl group at the terminus of
CA   the side-chain.
//
ID   4.2.2.13
DE   Exo-(1->4)-alpha-D-glucan lyase.
AN   Alpha-1,4-glucan 1,5-anhydro-D-fructose eliminase.
AN   Alpha-1,4-glucan exo-lyase.
AN   Alpha-1,4-glucan lyase.
AN   Exo-(1,4)-alpha-D-glucan lyase.
AN   Exo-alpha-1,4-glucan lyase.
CA   Linear alpha-glucan = (n-1) 1,5-anhydro-D-fructose + D-glucose.
CC   -!- Catalyzes the sequential degradation of (1->4)-alpha-D-glucans from
CC       the non-reducing end with the release of 1,5-anhydro-D-fructose.
CC   -!- Thus, for an alpha-glucan containing n (1->4)-linked glucose units,
CC       the final products are 1 glucose plus (n-1) 1,5-anhydro-D-fructose.
CC   -!- Maltose, maltosaccharides and amylose are all completely degraded.
CC   -!- Does not degrade (1->6)-alpha-gucosidic bonds and thus the
CC       degradation of a branched glucan, such as amylopectin or glycogen,
CC       will result in the formation of 1,5-anhydro-D-fructose plus a limit
CC       dextrin.
CC   -!- Other enzymes involved in the anhydrofructose pathway are
CC       EC 4.2.1.110, EC 4.2.1.111 and EC 5.3.3.15.
//
ID   4.2.2.14
DE   Glucuronan lyase.
CA   Eliminative cleavage of (1->4)-beta-D-glucuronans to give
CA   oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their
CA   non-reducing ends. Complete degradation of glucuronans results in the
CA   formation of tetrasaccharides.
//
ID   4.2.2.15
DE   Anhydrosialidase.
AN   Anhydroneuraminidase.
AN   Sialglycoconjugate N-acylneuraminylhydrolase (2,7-cyclizing).
AN   Sialidase L.
CA   Elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides,
CA   releasing 2,7-anhydro-alpha-N-acetylneuraminate.
CC   -!- Also acts on N-glycolylneuraminate glycosides.
CC   -!- Cf. EC 3.2.1.18 and EC 3.2.1.129.
CC   -!- Formerly EC 3.2.1.138.
DR   Q27701, NANL_MACDE ;
//
ID   4.2.2.16
DE   Levan fructotransferase (DFA-IV-forming).
AN   2,6-beta-D-fructan D-fructosyl-D-fructosyltransferase (forming di-beta-D-
AN   fructofuranose 2,6':2',6-dianhydride).
AN   Levan fructotransferase.
CA   Produces di-beta-D-fructofuranose 2,6':2',6-dianhydride (DFA IV) by
CA   successively eliminating the diminishing (2->6)-beta-D-fructan (levan)
CA   chain from the terminal D-fructosyl-D-fructosyl disaccharide.
CC   -!- This enzyme, like EC 4.2.2.17 and EC 4.2.2.18 eliminates the fructan
CC       chain from the terminal disaccharide leaving a difructose
CC       dianhydride.
CC   -!- These enzymes have long been known as fructotransferases, so this is
CC       retained in the description (official name).
CC   -!- Since the transfer is intramolecular, the reaction is an elimination
CC       and, hence, the enzyme is a lyase, belonging in enzyme class 4.-.-.-.
//
ID   4.2.2.17
DE   Inulin fructotransferase (DFA-I-forming).
AN   Inulin D-fructosyl-D-fructosyltransferase (1,2':1',2-dianhydride-
AN   forming).
AN   Inulin D-fructosyl-D-fructosyltransferase (forming alpha-D-fructofuranose
AN   beta-D-fructofuranose 1,2':1',2-dianhydride).
AN   Inulin fructotransferase (depolymerizing, difructofuranose-1,2':2',1-
AN   dianhydride-forming).
AN   Inulin fructotransferase (DFA-I-producing).
CA   Produces alpha-D-fructofuranose beta-D-fructofuranose
CA   1,2':2,1'-dianhydride (DFA I) by successively eliminating the diminishing
CA   (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-
CA   fructosyl disaccharide.
CC   -!- This enzyme, like EC 4.2.2.16 and EC 4.2.2.18 eliminates the fructan
CC       chain from the terminal disaccharide leaving a difructose
CC       dianhydride.
CC   -!- These enzymes have long been known as fructotransferases, so this is
CC       retained in the description (official name).
CC   -!- Since the transfer is intramolecular, the reaction is an elimination
CC       and, hence, the enzyme is a lyase, belonging in enzyme class 4.-.-.-.
CC   -!- Formerly EC 2.4.1.200.
DR   P19870, INU2_ARTGO ;
//
ID   4.2.2.18
DE   Inulin fructotransferase (DFA-III-forming).
AN   Inulase II.
AN   Inulin D-fructosyl-D-fructosyltransferase (1,2':2,3'-dianhydride-
AN   forming).
AN   Inulin D-fructosyl-D-fructosyltransferase (forming alpha-D-fructofuranose
AN   beta-D-fructofuranose 1,2':2,3'-dianhydride).
AN   Inulin fructotransferase (depolymerizing).
AN   Inulin fructotransferase (depolymerizing, difructofuranose-
AN   1,2':2,3'-dianhydride-forming).
AN   Inulin fructotransferase (DFA-III-producing).
AN   Inulinase II.
CA   Produces alpha-D-fructofuranose beta-D-fructofuranose
CA   1,2':2,3'-dianhydride (DFA III) by successively eliminating the
CA   diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal
CA   D-fructosyl-D-fructosyl disaccharide.
CC   -!- This enzyme, like EC 4.2.2.16 and EC 4.2.2.17 eliminates the fructan
CC       chain from the terminal disaccharide leaving a difructose
CC       dianhydride.
CC   -!- These enzymes have long been known as fructotransferases, so this is
CC       retained in the description (official name).
CC   -!- Since the transfer is intramolecular, the reaction is an elimination
CC       and, hence, the enzyme is a lyase, belonging in enzyme class 4.-.-.-.
CC   -!- Formerly EC 2.4.1.93.
//
ID   4.2.2.19
DE   Chondroitin B lyase.
AN   ChonB.
AN   Chondroitinase B.
CA   Eliminative cleavage of dermatan sulfate containing (1->4)-beta-D-
CA   hexosaminyl and (1->3)-beta-D-glucurosonyl or (1->3)-alpha-L-iduronosyl
CA   linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl
CA   groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (Delta-
CA   UA-GalNAc-4S).
CC   -!- This is the only lyase that is known to be specific for dermatan
CC       sulfate as substrate.
CC   -!- The minimum substrate length required for catalysis is a
CC       tetrasaccharide.
CC   -!- In general, chondroitin sulfate (CS) and dermatan sulfate (DS) chains
CC       comprise a linkage region, a chain cap and a repeat region.
CC   -!- The repeat region of CS is a repeating disaccharide of glucuronic
CC       acid (GlcA) and N-acetylgalactosamine (GalNAc) [-4)GlcA(beta-1-
CC       3)GalNAc(beta-1-](n), which may be O-sulfated on the C-4 and/or C-6
CC       of GalNAc and C-2 of GlcA.
CC   -!- GlcA residues of CS may be epimerized to iduronic acid (IdoA) forming
CC       the repeating disaccharide [-4)IdoA(alpha-1-3)GalNAc(beta-1-](n) of
CC       DS.
CC   -!- Both the concentrations and locations of sulfate-ester substituents
CC       vary with glucosaminoglycan source.
DR   Q46079, CSLB_PEDHD ;
//
ID   4.2.2.20
DE   Chondroitin-sulfate-ABC endolyase.
AN   Chondroitin ABC eliminase.
AN   Chondroitin ABC lyase.
AN   Chondroitin sulfate ABC endoeliminase.
AN   Chondroitin sulfate ABC endolyase.
AN   Chondroitin sulfate ABC lyase.
AN   Chondroitinase.
AN   Chondroitinase ABC.
AN   ChS ABC lyase.
AN   ChS ABC lyase I.
CA   Endolytic cleavage of (1->4)-beta-galactosaminic bonds between
CA   N-acetylgalactosamine and either D-glucuronic acid or L-iduronic acid to
CA   produce a mixture of Delta(4)-unsaturated oligosaccharides of different
CA   sizes that are ultimately degraded to Delta(4)-unsaturated tetra- and
CA   disaccharides.
CC   -!- Degrades a variety of glycosaminoglycans of the chondroitin-sulfate-
CC       and dermatan-sulfate type.
CC   -!- Chondroitin sulfate, chondroitin-sulfate proteoglycan and dermatan
CC       sulfate are the best substrates but the enzyme can also act on
CC       hyaluronan at a much lower rate.
CC   -!- Keratan sulfate, heparan sulfate and heparin are not substrates.
CC   -!- In general, chondroitin sulfate (CS) and dermatan sulfate (DS) chains
CC       comprise a linkage region, a chain cap and a repeat region.
CC   -!- The repeat region of CS is a repeating disaccharide of glucuronic
CC       acid (GlcA) and N-acetylgalactosamine (GalNAc) [-4)GlcA(beta-1-
CC       3)GalNAc(beta-1-](n), which may be O-sulfated on the C-4 and/or C-6
CC       of GalNAc and C-2 of GlcA.
CC   -!- GlcA residues of CS may be epimerized to iduronic acid (IdoA) forming
CC       the repeating disaccharide [-4)IdoA(alpha-1-3)GalNAc(beta-1-](n) of
CC       DS.
CC   -!- Both the concentrations and locations of sulfate-ester substituents
CC       vary with glucosaminoglycan source.
CC   -!- The related enzyme EC 4.2.2.21 has the same substrate specificity but
CC       removes disaccharide residues from the non-reducing ends of both
CC       polymeric chondroitin sulfates and their oligosaccharide fragments
CC       produced by EC 4.2.2.20.
CC   -!- Formerly EC 4.2.2.4 and EC 4.2.99.6.
DR   P59807, CABC_PROVU ;
//
ID   4.2.2.21
DE   Chondroitin-sulfate-ABC exolyase.
AN   Chondroitin ABC eliminase.
AN   Chondroitin ABC lyase.
AN   Chondroitin sulfate ABC exoeliminase.
AN   Chondroitin sulfate ABC exolyase.
AN   Chondroitin sulfate ABC lyase.
AN   Chondroitinase.
AN   Chondroitinase ABC.
AN   ChS ABC lyase.
AN   ChS ABC lyase II.
CA   Exolytic removal of Delta(4)-unsaturated disaccharide residues from the
CA   non-reducing ends of both polymeric chondroitin/dermatan sulfates and
CA   their oligosaccharide fragments.
CC   -!- Degrades a variety of glycosaminoglycans of the chondroitin-sulfate-
CC       and dermatan-sulfate type.
CC   -!- Chondroitin sulfate, chondroitin-sulfate proteoglycan and dermatan
CC       sulfate are the best substrates but the enzyme can also act on
CC       hyaluronan at a much lower rate.
CC   -!- The related enzyme EC 4.2.2.20 has the same substrate specificity but
CC       produces a mixture of oligosaccharides of different sizes that are
CC       ultimately degraded to tetra- and disaccharides.
CC   -!- Both enzymes act by the removal of a relatively acidic C-5 proton of
CC       the uronic acid followed by the elimination of a 4-linked hexosamine,
CC       resulting in the formation of an unsaturated C4-C5 bond on the
CC       hexuronic acid moiety of the products.
CC   -!- Formerly EC 4.2.2.4 and EC 4.2.99.6.
//
ID   4.2.2.22
DE   Pectate trisaccharide-lyase.
AN   Exopectate-lyase.
AN   Pectate lyase A.
CA   Eliminative cleavage of unsaturated trigalacturonate as the major product
CA   from the reducing end of polygalacturonic acid/pectate.
CC   -!- Differs in specificity from EC 4.2.2.9 as the predominant action is
CC       removal of a trisaccharide rather than a disaccharide from the
CC       reducing end.
CC   -!- Disaccharides and tetrasaccharides may also be removed.
DR   Q65DC2, PTLY_BACLD ;  Q8GCB2, PTLY_BACLI ;  B1B6T1, PTLY_BACSP ;
DR   Q9WYR4, PTLY_THEMA ;  B1L969, PTLY_THESQ ;
//
ID   4.2.2.n1
DE   Peptidoglycan lytic exotransglycosylase.
AN   Exomuramidase.
AN   Murein lyase F.
CA   Exolytic cleavage of the (1->4)-beta-glycosidic linkage between
CA   N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues
CA   in peptidoglycan, from either the reducing or the non-reducing ends of
CA   the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond
CA   in the MurNAc residue.
DR   P57531, MLTA_BUCAI ;  Q8K9A7, MLTA_BUCAP ;  P0A936, MLTA_ECO57 ;
DR   P0A935, MLTA_ECOLI ;  Q9KPQ4, MLTA_VIBCH ;  P41052, MLTB_ECOLI ;
DR   A3N339, MLTC_ACTP2 ;  A6VLS0, MLTC_ACTSZ ;  A8API2, MLTC_CITK8 ;
DR   A7ZR89, MLTC_ECO24 ;  Q8XCS6, MLTC_ECO57 ;  A8A4A6, MLTC_ECOHS ;
DR   A1AFE9, MLTC_ECOK1 ;  Q0TDN8, MLTC_ECOL5 ;  P0C067, MLTC_ECOL6 ;
DR   B1ISK6, MLTC_ECOLC ;  P0C066, MLTC_ECOLI ;  Q1R762, MLTC_ECOUT ;
DR   A4WEA0, MLTC_ENT38 ;  A7MLX9, MLTC_ENTS8 ;  Q6D8K0, MLTC_ERWCT ;
DR   Q7VKB7, MLTC_HAEDU ;  Q4QMD8, MLTC_HAEI8 ;  A5UDW4, MLTC_HAEIE ;
DR   A5UHR5, MLTC_HAEIG ;  P44049, MLTC_HAEIN ;  Q0I513, MLTC_HAES1 ;
DR   B0UWE6, MLTC_HAES2 ;  A6TDX1, MLTC_KLEP7 ;  Q65VT8, MLTC_MANSM ;
DR   Q9CLB8, MLTC_PASMU ;  Q7N7I2, MLTC_PHOLL ;  A9MQR3, MLTC_SALAR ;
DR   Q57K03, MLTC_SALCH ;  Q5PMM0, MLTC_SALPA ;  A9N4R0, MLTC_SALPB ;
DR   Q8Z3T9, MLTC_SALTI ;  Q8ZM39, MLTC_SALTY ;  A8GJ50, MLTC_SERP5 ;
DR   Q31WM5, MLTC_SHIBS ;  Q32C32, MLTC_SHIDS ;  Q0T0S4, MLTC_SHIF8 ;
DR   Q83Q83, MLTC_SHIFL ;  Q3YXF0, MLTC_SHISS ;  Q2NRB3, MLTC_SODGM ;
DR   A1JPV7, MLTC_YERE8 ;  A7FEX3, MLTC_YERP3 ;  Q1CB94, MLTC_YERPA ;
DR   Q8ZHE6, MLTC_YERPE ;  Q1CEV1, MLTC_YERPN ;  A4TI58, MLTC_YERPP ;
DR   Q666M2, MLTC_YERPS ;  P0AEZ8, MLTD_ECOL6 ;  P0AEZ7, MLTD_ECOLI ;
DR   P57352, MLTE_BUCAI ;  Q89AM2, MLTE_BUCBP ;  Q0A9W6, MLTF1_ALHEH;
DR   Q0A9T8, MLTF2_ALHEH;  A3N214, MLTF_ACTP2 ;  B3GYE5, MLTF_ACTP7 ;
DR   B0BQV5, MLTF_ACTPJ ;  A6VMD7, MLTF_ACTSZ ;  A0KJ50, MLTF_AERHH ;
DR   A4SNZ5, MLTF_AERS4 ;  Q0VRG6, MLTF_ALCBS ;  B4RVK5, MLTF_ALTMD ;
DR   B3PLH7, MLTF_CELJU ;  Q1QZB1, MLTF_CHRSD ;  A8AD27, MLTF_CITK8 ;
DR   Q47XX8, MLTF_COLP3 ;  A8ZWR8, MLTF_DESOH ;  B3Y154, MLTF_ECO11 ;
DR   A7ZQ01, MLTF_ECO24 ;  Q8XA45, MLTF_ECO57 ;  B1XB33, MLTF_ECODH ;
DR   A8A366, MLTF_ECOHS ;  A1AE89, MLTF_ECOK1 ;  Q0TET0, MLTF_ECOL5 ;
DR   Q8FF25, MLTF_ECOL6 ;  B1IVR9, MLTF_ECOLC ;  P0AGC5, MLTF_ECOLI ;
DR   B1LP71, MLTF_ECOSM ;  Q1R8H6, MLTF_ECOUT ;  A4WDC7, MLTF_ENT38 ;
DR   A7MGZ5, MLTF_ENTS8 ;  Q6D237, MLTF_ERWCT ;  B2VEB4, MLTF_ERWT9 ;
DR   Q7VN03, MLTF_HAEDU ;  Q4QNV4, MLTF_HAEI8 ;  A5UAQ3, MLTF_HAEIE ;
DR   A5UG36, MLTF_HAEIG ;  P44587, MLTF_HAEIN ;  Q0I361, MLTF_HAES1 ;
DR   B0UUK3, MLTF_HAES2 ;  Q2SK06, MLTF_HAHCH ;  Q5QWY4, MLTF_IDILO ;
DR   A6TCH2, MLTF_KLEP7 ;  A0L862, MLTF_MAGSM ;  Q65RJ5, MLTF_MANSM ;
DR   A1U3J1, MLTF_MARAV ;  Q0AQY9, MLTF_MARMM ;  Q1H288, MLTF_METFK ;
DR   Q2Y6L9, MLTF_NITMU ;  Q9CPJ2, MLTF_PASMU ;  Q6LU25, MLTF_PHOPR ;
DR   Q48LX4, MLTF_PSE14 ;  A6V102, MLTF_PSEA7 ;  Q02RN8, MLTF_PSEAB ;
DR   Q9HXN1, MLTF_PSEAE ;  Q1I5L3, MLTF_PSEE4 ;  Q4KHS7, MLTF_PSEF5 ;
DR   Q3IHZ1, MLTF_PSEHT ;  A4XXV1, MLTF_PSEMY ;  A5VZC8, MLTF_PSEP1 ;
DR   Q3KHL5, MLTF_PSEPF ;  B0KRE9, MLTF_PSEPG ;  Q88P17, MLTF_PSEPK ;
DR   B1JDH3, MLTF_PSEPW ;  Q886W7, MLTF_PSESM ;  Q4ZX03, MLTF_PSEU2 ;
DR   A4VP14, MLTF_PSEU5 ;  Q21KP0, MLTF_SACD2 ;  A9MGY7, MLTF_SALAR ;
DR   Q57LE4, MLTF_SALCH ;  Q5PIH0, MLTF_SALPA ;  A9N1U5, MLTF_SALPB ;
DR   Q8Z4L5, MLTF_SALTI ;  Q8ZN28, MLTF_SALTY ;  A8GI11, MLTF_SERP5 ;
DR   A1S850, MLTF_SHEAM ;  A3D6V0, MLTF_SHEB5 ;  A6WQN7, MLTF_SHEB8 ;
DR   A9KWW4, MLTF_SHEB9 ;  Q12PR8, MLTF_SHEDO ;  Q085S2, MLTF_SHEFN ;
DR   B0TLJ6, MLTF_SHEHH ;  A3QCH2, MLTF_SHELP ;  Q8EC56, MLTF_SHEON ;
DR   A8H256, MLTF_SHEPA ;  A4Y8T1, MLTF_SHEPC ;  A0KUK5, MLTF_SHESA ;
DR   A8FY01, MLTF_SHESH ;  Q0HKV0, MLTF_SHESM ;  Q0HX48, MLTF_SHESR ;
DR   A1RHR2, MLTF_SHESW ;  B1KLC4, MLTF_SHEWM ;  B2TXX1, MLTF_SHIB3 ;
DR   Q31XS9, MLTF_SHIBS ;  Q32D14, MLTF_SHIDS ;  Q0T1W2, MLTF_SHIF8 ;
DR   P0AGC6, MLTF_SHIFL ;  Q3YYZ7, MLTF_SHISS ;  Q2NS21, MLTF_SODGM ;
DR   Q30PQ0, MLTF_SULDN ;  Q3SJH8, MLTF_THIDA ;  A5F353, MLTF_VIBC3 ;
DR   Q9KTN5, MLTF_VIBCH ;  Q5E750, MLTF_VIBF1 ;  A7MSG2, MLTF_VIBHB ;
DR   Q87RW1, MLTF_VIBPA ;  Q8DF80, MLTF_VIBVU ;  Q7MN72, MLTF_VIBVY ;
DR   A1JKM2, MLTF_YERE8 ;  A7FFU9, MLTF_YERP3 ;  Q1C5E6, MLTF_YERPA ;
DR   B2KA37, MLTF_YERPB ;  Q74SQ6, MLTF_YERPE ;  A9R413, MLTF_YERPG ;
DR   Q1CKD3, MLTF_YERPN ;  A4TMX8, MLTF_YERPP ;  Q667W0, MLTF_YERPS ;
DR   B1JRW4, MLTF_YERPY ;  P0AGC4, SLT_ECO57  ;  P0AGC3, SLT_ECOLI  ;
DR   P39433, SLT_ENTCL  ;  P44888, SLT_HAEIN  ;  P39434, SLT_SALTY  ;
//
ID   4.2.2.n2
DE   Peptidoglycan lytic endotransglycosylase.
CA   Endolytic cleavage of the (1->4)-beta-glycosidic linkage between
CA   N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues
CA   in peptidoglycan with concomitant formation of a 1,6-anhydrobond in the
CA   MurNAc residue.
DR   Q83RQ0, EMTAL_SHIFL;  A8AFS5, EMTA_CITK8 ;  B7UQ77, EMTA_ECO27 ;
DR   B7MK90, EMTA_ECO45 ;  B7LGV3, EMTA_ECO55 ;  Q8XDJ7, EMTA_ECO57 ;
DR   B5YXL7, EMTA_ECO5E ;  B7NUV4, EMTA_ECO7I ;  B7MTX1, EMTA_ECO81 ;
DR   B7LXA7, EMTA_ECO8A ;  C4ZTN4, EMTA_ECOBW ;  B1XAN4, EMTA_ECODH ;
DR   A1AAB6, EMTA_ECOK1 ;  Q0TII2, EMTA_ECOL5 ;  P59243, EMTA_ECOL6 ;
DR   B1IU99, EMTA_ECOLC ;  P0C960, EMTA_ECOLI ;  B7N3Z9, EMTA_ECOLU ;
DR   B1LHX3, EMTA_ECOSM ;  Q1RCQ2, EMTA_ECOUT ;  A4WBE8, EMTA_ENT38 ;
DR   A7MKC3, EMTA_ENTS8 ;  B7LSJ1, EMTA_ESCF3 ;  B5XQ85, EMTA_KLEP3 ;
DR   A6TAW0, EMTA_KLEP7 ;  Q57NL3, EMTA_SALCH ;  B5R2X1, EMTA_SALEP ;
DR   B5R901, EMTA_SALG2 ;  Q5PN08, EMTA_SALPA ;  A9MVX1, EMTA_SALPB ;
DR   C0Q334, EMTA_SALPC ;  B5BI54, EMTA_SALPK ;  Q8XGT6, EMTA_SALTI ;
DR   Q7CQE4, EMTA_SALTY ;  Q31ZN3, EMTA_SHIBS ;  Q32H22, EMTA_SHIDS ;
DR   Q0T5K7, EMTA_SHIF8 ;  Q83RP9, EMTA_SHIFL ;  Q3Z2V5, EMTA_SHISS ;
//
ID   4.2.3.1
DE   Threonine synthase.
CA   O-phospho-L-homoserine + H(2)O = L-threonine + phosphate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Formerly EC 4.2.99.2.
PR   PROSITE; PDOC00149;
DR   Q9S7B5, THRC1_ARATH;  Q9SSP5, THRC2_ARATH;  Q00063, THRC_ASHGO ;
DR   Q9K7E3, THRC_BACHD ;  P09123, THRC_BACSL ;  P04990, THRC_BACSU ;
DR   P57289, THRC_BUCAI ;  Q8K9V1, THRC_BUCAP ;  Q89AR5, THRC_BUCBP ;
DR   P23669, THRC_CORGL ;  P00934, THRC_ECOLI ;  P44503, THRC_HAEIN ;
DR   Q9ZMX5, THRC_HELPJ ;  O24924, THRC_HELPY ;  Q8TQD4, THRC_METAC ;
DR   P37145, THRC_METGL ;  Q58860, THRC_METJA ;  P66903, THRC_MYCBO ;
DR   P45837, THRC_MYCLE ;  A0R220, THRC_MYCS2 ;  P66902, THRC_MYCTU ;
DR   P29363, THRC_PSEAE ;  Q42598, THRC_SCHPO ;  P27735, THRC_SERMA ;
DR   Q9MT28, THRC_SOLTU ;  P74193, THRC_SYNY3 ;  P16120, THRC_YEAST ;
//
ID   4.2.3.2
DE   Ethanolamine-phosphate phospho-lyase.
AN   Amino alcohol O-phosphate phospholyase.
AN   O-phosphoethanolamine-phospholyase.
AN   O-phosphorylethanol-amine phospho-lyase.
CA   Ethanolamine phosphate + H(2)O = acetaldehyde + NH(3) + phosphate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Also acts on D- (or L)-1-aminopropan-2-ol O-phosphate.
CC   -!- Formerly EC 4.2.99.7.
//
ID   4.2.3.3
DE   Methylglyoxal synthase.
CA   Glycerone phosphate = methylglyoxal + phosphate.
CC   -!- Does not act on D-glyceraldehyde 3-phosphate.
CC   -!- Formerly EC 4.2.99.11.
PR   PROSITE; PDOC01037;
DR   A9NF94, MGSA_ACHLI ;  A3N2E6, MGSA_ACTP2 ;  B3H2I5, MGSA_ACTP7 ;
DR   B0BR90, MGSA_ACTPJ ;  A4SIB9, MGSA_AERS4 ;  B9J6R7, MGSA_AGRRK ;
DR   Q8UIV6, MGSA_AGRT5 ;  B9JYQ6, MGSA_AGRVS ;  B6EI79, MGSA_ALISL ;
DR   A6TQI6, MGSA_ALKMQ ;  B9MRV5, MGSA_ANATD ;  A7Z5Z9, MGSA_BACA2 ;
DR   C3P5Q3, MGSA_BACAA ;  C3L8Q6, MGSA_BACAC ;  A0RBY7, MGSA_BACAH ;
DR   Q81ST9, MGSA_BACAN ;  B7JH18, MGSA_BACC0 ;  Q73AW0, MGSA_BACC1 ;
DR   B7IPB1, MGSA_BACC2 ;  C1EN30, MGSA_BACC3 ;  B7HHT7, MGSA_BACC4 ;
DR   B7HL47, MGSA_BACC7 ;  A7GN71, MGSA_BACCN ;  B9IVQ6, MGSA_BACCQ ;
DR   Q81FP3, MGSA_BACCR ;  Q63DJ9, MGSA_BACCZ ;  Q9KC92, MGSA_BACHD ;
DR   Q6HL22, MGSA_BACHK ;  Q65I51, MGSA_BACLD ;  A8FEI2, MGSA_BACP2 ;
DR   Q5WGQ3, MGSA_BACSK ;  P42980, MGSA_BACSU ;  A9VME4, MGSA_BACWK ;
DR   Q0SNF0, MGSA_BORAP ;  O51339, MGSA_BORBU ;  B7J1T7, MGSA_BORBZ ;
DR   Q661Q5, MGSA_BORGA ;  C0ZCG5, MGSA_BREBN ;  B2SC33, MGSA_BRUA1 ;
DR   Q2YJP0, MGSA_BRUA2 ;  P0CB36, MGSA_BRUAB ;  A9MCX4, MGSA_BRUC2 ;
DR   C0RMI7, MGSA_BRUMB ;  P0A3Q2, MGSA_BRUME ;  A5VVV1, MGSA_BRUO2 ;
DR   A9WW58, MGSA_BRUSI ;  P0A3Q3, MGSA_BRUSU ;  B1YU46, MGSA_BURA4 ;
DR   Q1BUX2, MGSA_BURCA ;  B1JW38, MGSA_BURCC ;  A0K965, MGSA_BURCH ;
DR   B4E5R3, MGSA_BURCJ ;  Q0BD88, MGSA_BURCM ;  A9AJK3, MGSA_BURM1 ;
DR   A3MI51, MGSA_BURM7 ;  A2S4A9, MGSA_BURM9 ;  Q62IJ3, MGSA_BURMA ;
DR   A1V2G6, MGSA_BURMS ;  A3NT52, MGSA_BURP0 ;  Q3JUF3, MGSA_BURP1 ;
DR   A3N7G3, MGSA_BURP6 ;  Q63VS6, MGSA_BURPS ;  Q39EA4, MGSA_BURS3 ;
DR   Q2SZS7, MGSA_BURTA ;  A4JGH2, MGSA_BURVG ;  A4XKM4, MGSA_CALS8 ;
DR   Q3AEV6, MGSA_CARHZ ;  B3PFP8, MGSA_CELJU ;  A8AIB5, MGSA_CITK8 ;
DR   Q97IN6, MGSA_CLOAB ;  A6LPD6, MGSA_CLOB8 ;  B2V099, MGSA_CLOBA ;
DR   B2TK64, MGSA_CLOBB ;  Q18B16, MGSA_CLOD6 ;  A0PZH3, MGSA_CLONN ;
DR   Q0TRM9, MGSA_CLOP1 ;  Q8XLN2, MGSA_CLOPE ;  Q0SU08, MGSA_CLOPS ;
DR   A9KFK7, MGSA_COXBN ;  A9ND61, MGSA_COXBR ;  Q83D86, MGSA_COXBU ;
DR   Q46YB8, MGSA_CUPPJ ;  B3R3G1, MGSA_CUPTR ;  C6BZQ4, MGSA_DESAD ;
DR   Q30ZX0, MGSA_DESDG ;  A7ZK67, MGSA_ECO24 ;  B7UN42, MGSA_ECO27 ;
DR   B7MIB7, MGSA_ECO45 ;  B7LE63, MGSA_ECO55 ;  P0A732, MGSA_ECO57 ;
DR   B5YT93, MGSA_ECO5E ;  B7NLF4, MGSA_ECO7I ;  B7MS74, MGSA_ECO81 ;
DR   B7M892, MGSA_ECO8A ;  C4ZQ89, MGSA_ECOBW ;  B1X8R7, MGSA_ECODH ;
DR   A7ZYR5, MGSA_ECOHS ;  Q8FJ74, MGSA_ECOL6 ;  B1IVW9, MGSA_ECOLC ;
DR   P0A731, MGSA_ECOLI ;  B7N3C6, MGSA_ECOLU ;  B6I938, MGSA_ECOSE ;
DR   B1LJ35, MGSA_ECOSM ;  C5BDP0, MGSA_EDWI9 ;  A4W8X5, MGSA_ENT38 ;
DR   Q837A4, MGSA_ENTFA ;  A7ME47, MGSA_ENTS8 ;  Q6D6C8, MGSA_ERWCT ;
DR   B2VDH0, MGSA_ERWT9 ;  B7LNX3, MGSA_ESCF3 ;  B1YKL9, MGSA_EXIS2 ;
DR   C4L0B0, MGSA_EXISA ;  Q5KXW7, MGSA_GEOKA ;  C5D3B8, MGSA_GEOSW ;
DR   A4IQ66, MGSA_GEOTN ;  Q4QJW2, MGSA_HAEI8 ;  A5UBP8, MGSA_HAEIE ;
DR   A5UF70, MGSA_HAEIG ;  P45120, MGSA_HAEIN ;  Q0I4N3, MGSA_HAES1 ;
DR   B0UW70, MGSA_HAES2 ;  Q2SK75, MGSA_HAHCH ;  B5XY41, MGSA_KLEP3 ;
DR   Q38WH3, MGSA_LACSS ;  Q04UA7, MGSA_LEPBJ ;  Q053R1, MGSA_LEPBL ;
DR   Q72NU6, MGSA_LEPIC ;  Q8F7N5, MGSA_LEPIN ;  Q92AA2, MGSA_LISIN ;
DR   C1KWK6, MGSA_LISMC ;  Q71YA9, MGSA_LISMF ;  B8DC20, MGSA_LISMH ;
DR   Q8Y5Z7, MGSA_LISMO ;  A0AK11, MGSA_LISW6 ;  B1HTF1, MGSA_LYSSC ;
DR   Q65UB4, MGSA_MANSM ;  Q2RJ00, MGSA_MOOTA ;  B2A7A5, MGSA_NATTJ ;
DR   Q8EQD4, MGSA_OCEIH ;  A6WYJ6, MGSA_OCHA4 ;  Q9CNN3, MGSA_PASMU ;
DR   C6DKX3, MGSA_PECCP ;  Q7N5Z7, MGSA_PHOLL ;  Q6LST5, MGSA_PHOPR ;
DR   B4EVE1, MGSA_PROMH ;  Q15X77, MGSA_PSEA6 ;  Q3IES7, MGSA_PSEHT ;
DR   A1SR75, MGSA_PSYIN ;  Q1LQ98, MGSA_RALME ;  Q8XXD0, MGSA_RALSO ;
DR   B3PXK7, MGSA_RHIE6 ;  Q2KDT8, MGSA_RHIEC ;  Q92T28, MGSA_RHIME ;
DR   C3MBY3, MGSA_RHISN ;  Q21L65, MGSA_SACD2 ;  B5F1W0, MGSA_SALA4 ;
DR   A9MHS6, MGSA_SALAR ;  Q57QS7, MGSA_SALCH ;  B5FR06, MGSA_SALDC ;
DR   B5QZG6, MGSA_SALEP ;  B5R6C9, MGSA_SALG2 ;  B4TE03, MGSA_SALHS ;
DR   B4T206, MGSA_SALNS ;  Q5PGC6, MGSA_SALPA ;  A9N6W4, MGSA_SALPB ;
DR   C0Q8C9, MGSA_SALPC ;  B5BBK4, MGSA_SALPK ;  B4TSI9, MGSA_SALSV ;
DR   P65351, MGSA_SALTI ;  P65350, MGSA_SALTY ;  A8GCM4, MGSA_SERP5 ;
DR   B2TTT1, MGSA_SHIB3 ;  P0A733, MGSA_SHIFL ;  Q2NU68, MGSA_SODGM ;
DR   Q67NW2, MGSA_SYMTH ;  C5BMN7, MGSA_TERTT ;  Q9X0R7, MGSA_THEMA ;
DR   B0KAD1, MGSA_THEP3 ;  B0K427, MGSA_THEPX ;  Q72HP3, MGSA_THET2 ;
DR   Q5SHD6, MGSA_THET8 ;  Q8RBB6, MGSA_THETN ;  Q9XCV1, MGSA_THETR ;
DR   P58761, MGSA_TRESO ;  A5EZV8, MGSA_VIBC3 ;  Q9KLN2, MGSA_VIBCH ;
DR   C3LVX6, MGSA_VIBCM ;  Q5E4D0, MGSA_VIBF1 ;  B5FF54, MGSA_VIBFM ;
DR   A7N2T8, MGSA_VIBHB ;  Q87ID3, MGSA_VIBPA ;  B7VS36, MGSA_VIBSL ;
DR   Q8D7M9, MGSA_VIBVU ;  Q7MEP0, MGSA_VIBVY ;  A1JMV3, MGSA_YERE8 ;
DR   A7FJS2, MGSA_YERP3 ;  Q1CA21, MGSA_YERPA ;  B2JYU0, MGSA_YERPB ;
DR   Q8ZG71, MGSA_YERPE ;  A9R2N5, MGSA_YERPG ;  Q1CGL4, MGSA_YERPN ;
DR   A4TKV8, MGSA_YERPP ;  Q66CE4, MGSA_YERPS ;  B1JQQ0, MGSA_YERPY ;
//
ID   4.2.3.4
DE   3-dehydroquinate synthase.
AN   3-dehydroquinate synthetase.
AN   5-dehydroquinate synthase.
AN   5-dehydroquinic acid synthetase.
AN   Dehydroquinate synthase.
CA   3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate +
CA   phosphate.
CF   Cobalt; NAD.
CC   -!- The hydrogen atoms on C-7 of the substrate are retained on C-2 of the
CC       products.
CC   -!- Formerly EC 4.6.1.3.
DR   A5H2Q8, ARO11_LODEL;  B6QWH9, ARO11_PENMQ;  A5H2P4, ARO12_LODEL;
DR   B6QCA7, ARO12_PENMQ;  C0NL63, ARO1_AJECG ;  C6HCG7, ARO1_AJECH ;
DR   A6R8Q8, ARO1_AJECN ;  C5G8R4, ARO1_AJEDR ;  C5JKE6, ARO1_AJEDS ;
DR   C5FQ73, ARO1_ARTOC ;  Q74ZZ1, ARO1_ASHGO ;  A1CP85, ARO1_ASPCL ;
DR   B0XRM8, ARO1_ASPFC ;  B8N4Q9, ARO1_ASPFN ;  Q4WS76, ARO1_ASPFU ;
DR   Q2UCP6, ARO1_ASPOR ;  Q0D0F3, ARO1_ASPTN ;  Q5AME2, ARO1_CANAL ;
DR   B9WFG1, ARO1_CANDC ;  Q6FIV4, ARO1_CANGA ;  C5M1X2, ARO1_CANTT ;
DR   C4Y9D5, ARO1_CLAL4 ;  C5PA86, ARO1_COCP7 ;  A8NMB4, ARO1_COPC7 ;
DR   P0CM23, ARO1_CRYNB ;  P0CM22, ARO1_CRYNJ ;  P07547, ARO1_EMENI ;
DR   Q6CJC4, ARO1_KLULA ;  B0D6H2, ARO1_LACBS ;  C5DN02, ARO1_LACTC ;
DR   A4RD09, ARO1_MAGO7 ;  A8QCB2, ARO1_MALGO ;  C7YZ74, ARO1_NECH7 ;
DR   A1D244, ARO1_NEOFI ;  Q8X071, ARO1_NEUCR ;  C1H8L1, ARO1_PARBA ;
DR   C1FYJ9, ARO1_PARBD ;  C0S433, ARO1_PARBP ;  B6HAA7, ARO1_PENCW ;
DR   Q0V3H0, ARO1_PHANO ;  C4R4R8, ARO1_PICPG ;  A3LSZ2, ARO1_PICST ;
DR   Q12659, ARO1_PNECA ;  B2B223, ARO1_PODAN ;  B6JVD0, ARO1_SCHJY ;
DR   Q9P7R0, ARO1_SCHPO ;  A7F7H0, ARO1_SCLS1 ;  Q5XNP0, ARO1_SCLSC ;
DR   D1ZA70, ARO1_SORMK ;  B8M0U4, ARO1_TALSN ;  Q8J294, ARO1_THACU ;
DR   C4JYG6, ARO1_UNCRE ;  Q4P8F6, ARO1_USTMA ;  C9SE96, ARO1_VERA1 ;
DR   Q6C1X5, ARO1_YARLI ;  B3LGE9, ARO1_YEAS1 ;  C7GIN5, ARO1_YEAS2 ;
DR   A6ZY89, ARO1_YEAS7 ;  C8Z543, ARO1_YEAS8 ;  P08566, ARO1_YEAST ;
DR   C5DVG6, ARO1_ZYGRC ;  B0CBS9, AROB_ACAM1 ;  Q6F7E5, AROB_ACIAD ;
DR   B7GVP5, AROB_ACIB3 ;  B7IAV6, AROB_ACIB5 ;  B2I0J2, AROB_ACIBC ;
DR   Q1IPF0, AROB_ACIBL ;  B0VQ34, AROB_ACIBS ;  A3M9I8, AROB_ACIBT ;
DR   B0V8M9, AROB_ACIBY ;  C1F548, AROB_ACIC5 ;  B7J629, AROB_ACIF2 ;
DR   B5EP40, AROB_ACIF5 ;  A3MYR5, AROB_ACTP2 ;  B3H035, AROB_ACTP7 ;
DR   A6VKZ5, AROB_ACTSZ ;  A0KN28, AROB_AERHH ;  Q9YEJ9, AROB_AERPE ;
DR   A4SK25, AROB_AERS4 ;  B9JBT6, AROB_AGRRK ;  Q8U9V0, AROB_AGRT5 ;
DR   B6EM44, AROB_ALISL ;  A6TL07, AROB_ALKMQ ;  A8MH15, AROB_ALKOO ;
DR   Q3M4V2, AROB_ANAVT ;  Q5P5P3, AROB_AROAE ;  A1R703, AROB_ARTAT ;
DR   B8H8V5, AROB_ARTCA ;  A0JX82, AROB_ARTS2 ;  A1KBQ4, AROB_AZOSB ;
DR   C1DHQ5, AROB_AZOVD ;  A7Z622, AROB_BACA2 ;  C3P5A4, AROB_BACAA ;
DR   C3L8S2, AROB_BACAC ;  A0RBX1, AROB_BACAH ;  Q81SV6, AROB_BACAN ;
DR   B7JH02, AROB_BACC0 ;  Q73AX8, AROB_BACC1 ;  B7IP95, AROB_BACC2 ;
DR   C1EN14, AROB_BACC3 ;  B7HHS1, AROB_BACC4 ;  B7HL27, AROB_BACC7 ;
DR   A7GN54, AROB_BACCN ;  B9IVN9, AROB_BACCQ ;  Q81FQ2, AROB_BACCR ;
DR   Q63DL5, AROB_BACCZ ;  Q9KCB6, AROB_BACHD ;  Q6HL38, AROB_BACHK ;
DR   Q65I29, AROB_BACLD ;  A8FEK4, AROB_BACP2 ;  Q5WGS7, AROB_BACSK ;
DR   P31102, AROB_BACSU ;  A9VMC6, AROB_BACWK ;  A1UQX3, AROB_BARBK ;
DR   Q6G1N8, AROB_BARHE ;  Q6G1H4, AROB_BARQU ;  A9IZS4, AROB_BART1 ;
DR   Q1LU62, AROB_BAUCH ;  Q7VRN3, AROB_BLOFL ;  Q492A5, AROB_BLOPB ;
DR   Q7WR84, AROB_BORBR ;  Q7W2B6, AROB_BORPA ;  Q7VT93, AROB_BORPE ;
DR   Q89XW8, AROB_BRAJA ;  A5ETC5, AROB_BRASB ;  Q2YR43, AROB_BRUA2 ;
DR   Q57AM9, AROB_BRUAB ;  A9M9B3, AROB_BRUC2 ;  C0RFR9, AROB_BRUMB ;
DR   P63615, AROB_BRUME ;  A5VSZ3, AROB_BRUO2 ;  B0CJD0, AROB_BRUSI ;
DR   P63616, AROB_BRUSU ;  P57604, AROB_BUCAI ;  Q8K939, AROB_BUCAP ;
DR   P59487, AROB_BUCBP ;  Q056Z3, AROB_BUCCC ;  B1YRS4, AROB_BURA4 ;
DR   Q1BRZ3, AROB_BURCA ;  B1JU67, AROB_BURCC ;  A0K3S0, AROB_BURCH ;
DR   B4E603, AROB_BURCJ ;  Q0BJ01, AROB_BURCM ;  A9ADP0, AROB_BURM1 ;
DR   A3MPY1, AROB_BURM7 ;  A2S718, AROB_BURM9 ;  Q62GB0, AROB_BURMA ;
DR   A1V8D7, AROB_BURMS ;  A3P066, AROB_BURP0 ;  Q3JMW1, AROB_BURP1 ;
DR   A3NED2, AROB_BURP6 ;  Q63Q57, AROB_BURPS ;  Q39KC4, AROB_BURS3 ;
DR   A4JAT5, AROB_BURVG ;  A7ZD95, AROB_CAMC1 ;  A7GYE1, AROB_CAMC5 ;
DR   A0RP96, AROB_CAMFF ;  A7I291, AROB_CAMHC ;  A8FM57, AROB_CAMJ8 ;
DR   A7H333, AROB_CAMJD ;  Q9PNT2, AROB_CAMJE ;  A1VZZ6, AROB_CAMJJ ;
DR   Q5HUF4, AROB_CAMJR ;  B9KG40, AROB_CAMLR ;  B8H332, AROB_CAUCN ;
DR   Q9A434, AROB_CAUCR ;  B0T8F3, AROB_CAUSK ;  Q5L5F1, AROB_CHLAB ;
DR   Q3AR94, AROB_CHLCH ;  Q822F7, AROB_CHLCV ;  Q255H6, AROB_CHLFF ;
DR   Q9PK25, AROB_CHLMU ;  B3QMM2, AROB_CHLP8 ;  Q9Z6M3, AROB_CHLPN ;
DR   B0B7T8, AROB_CHLT2 ;  Q3KLY7, AROB_CHLTA ;  B0BC03, AROB_CHLTB ;
DR   Q8KCK9, AROB_CHLTE ;  O84374, AROB_CHLTR ;  Q7NZU4, AROB_CHRVO ;
DR   A8AQU3, AROB_CITK8 ;  Q97KM3, AROB_CLOAB ;  A6M255, AROB_CLOB8 ;
DR   B2UYK8, AROB_CLOBA ;  B8I359, AROB_CLOCE ;  A5N6A8, AROB_CLOK5 ;
DR   Q0TTA0, AROB_CLOP1 ;  Q8XMJ3, AROB_CLOPE ;  Q0SV35, AROB_CLOPS ;
DR   Q894C9, AROB_CLOTE ;  A3DDJ2, AROB_CLOTH ;  Q489N3, AROB_COLP3 ;
DR   Q6NH04, AROB_CORDI ;  Q8FT31, AROB_COREF ;  A4QEJ6, AROB_CORGB ;
DR   Q9X5D2, AROB_CORGL ;  Q4JVG2, AROB_CORJK ;  P96749, AROB_CORP2 ;
DR   B6J4A4, AROB_COXB1 ;  B6J3I1, AROB_COXB2 ;  A9KBB1, AROB_COXBN ;
DR   A9NB81, AROB_COXBR ;  Q83AJ2, AROB_COXBU ;  Q0K669, AROB_CUPNH ;
DR   Q46WJ4, AROB_CUPPJ ;  B3R7B8, AROB_CUPTR ;  B1WUD4, AROB_CYAA5 ;
DR   B8HRK7, AROB_CYAP4 ;  B7KJH2, AROB_CYAP7 ;  B7K660, AROB_CYAP8 ;
DR   Q47JK6, AROB_DECAR ;  Q3Z988, AROB_DEHE1 ;  A5FRZ7, AROB_DEHSB ;
DR   Q3ZZN1, AROB_DEHSC ;  Q1IXK7, AROB_DEIGD ;  A4J3A3, AROB_DESRM ;
DR   A5EXS0, AROB_DICNV ;  B5YE18, AROB_DICT6 ;  B8E259, AROB_DICTD ;
DR   A7ZSR4, AROB_ECO24 ;  B7UK94, AROB_ECO27 ;  B7MD00, AROB_ECO45 ;
DR   B7L4R5, AROB_ECO55 ;  Q8X824, AROB_ECO57 ;  B5YTT8, AROB_ECO5E ;
DR   B7NMF2, AROB_ECO7I ;  B7N1G6, AROB_ECO81 ;  B7M1U1, AROB_ECO8A ;
DR   C4ZUP4, AROB_ECOBW ;  B1X736, AROB_ECODH ;  A8A5J6, AROB_ECOHS ;
DR   A1AGR6, AROB_ECOK1 ;  Q0TC78, AROB_ECOL5 ;  Q8FCV7, AROB_ECOL6 ;
DR   B1IP76, AROB_ECOLC ;  P07639, AROB_ECOLI ;  B7NDZ3, AROB_ECOLU ;
DR   B6I2U7, AROB_ECOSE ;  B1LHI4, AROB_ECOSM ;  Q1R5P8, AROB_ECOUT ;
DR   C5BGQ4, AROB_EDWI9 ;  A4WFH7, AROB_ENT38 ;  P0DH71, AROB_ENTFA ;
DR   F2MTI0, AROB_ENTFO ;  A7MKL4, AROB_ENTS8 ;  Q6CZQ9, AROB_ERWCT ;
DR   B2VJW7, AROB_ERWT9 ;  B7LS90, AROB_ESCF3 ;  B1YI19, AROB_EXIS2 ;
DR   C4L6N4, AROB_EXISA ;  Q14H73, AROB_FRAT1 ;  A7NBH0, AROB_FRATF ;
DR   Q2A418, AROB_FRATH ;  B2SGC9, AROB_FRATM ;  A0Q706, AROB_FRATN ;
DR   Q0BMF4, AROB_FRATO ;  Q5NFS1, AROB_FRATT ;  A4IYI9, AROB_FRATW ;
DR   Q8RF47, AROB_FUSNN ;  B5E8I9, AROB_GEOBB ;  Q5KXU5, AROB_GEOKA ;
DR   Q39X04, AROB_GEOMG ;  Q74BL6, AROB_GEOSL ;  C6E0S2, AROB_GEOSM ;
DR   C5D3E0, AROB_GEOSW ;  A4IQ88, AROB_GEOTN ;  A5GF05, AROB_GEOUR ;
DR   Q7NHM2, AROB_GLOVI ;  Q7VNR5, AROB_HAEDU ;  Q4QNY2, AROB_HAEI8 ;
DR   A5UAU8, AROB_HAEIE ;  A5UG10, AROB_HAEIG ;  P43879, AROB_HAEIN ;
DR   Q0I432, AROB_HAES1 ;  B0UTE6, AROB_HAES2 ;  A1WZA9, AROB_HALHL ;
DR   C4K6Q9, AROB_HAMD5 ;  Q7VHT1, AROB_HELHP ;  B6JKL2, AROB_HELP2 ;
DR   B5ZA49, AROB_HELPG ;  Q1CUM0, AROB_HELPH ;  Q9ZMF2, AROB_HELPJ ;
DR   B2USB4, AROB_HELPS ;  P56081, AROB_HELPY ;  Q0C627, AROB_HYPNA ;
DR   Q5QV59, AROB_IDILO ;  Q28PF8, AROB_JANSC ;  B5XTU7, AROB_KLEP3 ;
DR   A6TF13, AROB_KLEP7 ;  Q9CES8, AROB_LACLA ;  A2RMH5, AROB_LACLM ;
DR   Q02XB8, AROB_LACLS ;  Q88XU0, AROB_LACPL ;  Q38X86, AROB_LACSS ;
DR   C1D4Z4, AROB_LARHH ;  Q5X6H0, AROB_LEGPA ;  A5IFX9, AROB_LEGPC ;
DR   Q5ZX00, AROB_LEGPH ;  Q5WXX5, AROB_LEGPL ;  Q6AF95, AROB_LEIXX ;
DR   Q75FW3, AROB_LEPIC ;  Q8EXX1, AROB_LEPIN ;  B1MYC9, AROB_LEUCK ;
DR   Q03X08, AROB_LEUMM ;  Q92A81, AROB_LISIN ;  C1KWM7, AROB_LISMC ;
DR   Q71Y88, AROB_LISMF ;  B8DBZ9, AROB_LISMH ;  Q8Y5X6, AROB_LISMO ;
DR   A0AK39, AROB_LISW6 ;  B1HTD2, AROB_LYSSC ;  B9E6K7, AROB_MACCJ ;
DR   Q65R35, AROB_MANSM ;  A6W2T3, AROB_MARMS ;  Q60BY2, AROB_METCA ;
DR   B3DUF9, AROB_METI4 ;  B0JID6, AROB_MICAN ;  P0A4Z5, AROB_MYCBO ;
DR   A4TBX8, AROB_MYCGI ;  Q9CCS4, AROB_MYCLE ;  Q741J7, AROB_MYCPA ;
DR   P0A4Z4, AROB_MYCTU ;  A1T8F5, AROB_MYCVP ;  B2A259, AROB_NATTJ ;
DR   Q5FAD4, AROB_NEIG1 ;  B4RQ17, AROB_NEIG2 ;  O50468, AROB_NEIGO ;
DR   A9M1U4, AROB_NEIM0 ;  Q9JVW5, AROB_NEIMA ;  Q9JY01, AROB_NEIMB ;
DR   A1KS84, AROB_NEIMF ;  Q0AJ12, AROB_NITEC ;  Q82TB9, AROB_NITEU ;
DR   Q1QQW6, AROB_NITHX ;  Q2YB61, AROB_NITMU ;  Q3JEG3, AROB_NITOC ;
DR   A6Q3Y3, AROB_NITSB ;  Q3SVM8, AROB_NITWN ;  Q5YTK6, AROB_NOCFA ;
DR   B2J913, AROB_NOSP7 ;  Q8YVQ0, AROB_NOSS1 ;  Q8EQB7, AROB_OCEIH ;
DR   A6WXC7, AROB_OCHA4 ;  B1ZQS6, AROB_OPITP ;  A6LEZ7, AROB_PARD8 ;
DR   A1B1J4, AROB_PARDP ;  Q6MF52, AROB_PARUW ;  P57924, AROB_PASMU ;
DR   C6DGD4, AROB_PECCP ;  Q3A2N6, AROB_PELCD ;  Q3B315, AROB_PELLD ;
DR   A1AQL5, AROB_PELPD ;  A5D374, AROB_PELTS ;  Q4FNG5, AROB_PELUB ;
DR   B4RG33, AROB_PHEZH ;  Q7NA56, AROB_PHOLL ;  Q6LVF5, AROB_PHOPR ;
DR   Q6L1G8, AROB_PICTO ;  Q6A8I2, AROB_PROAC ;  A3PC83, AROB_PROM0 ;
DR   A2C1E0, AROB_PROM1 ;  A8G451, AROB_PROM2 ;  A2C9Z1, AROB_PROM3 ;
DR   A9BA66, AROB_PROM4 ;  A2BW03, AROB_PROM5 ;  Q31BK2, AROB_PROM9 ;
DR   Q7VBT3, AROB_PROMA ;  B4F0B1, AROB_PROMH ;  Q7V7S1, AROB_PROMM ;
DR   Q7V209, AROB_PROMP ;  A2BQG2, AROB_PROMS ;  Q46LM0, AROB_PROMT ;
DR   Q48PH0, AROB_PSE14 ;  Q15Y44, AROB_PSEA6 ;  A6VDF9, AROB_PSEA7 ;
DR   B7V3D1, AROB_PSEA8 ;  Q02EX9, AROB_PSEAB ;  P34002, AROB_PSEAE ;
DR   Q1IGA7, AROB_PSEE4 ;  Q4KJI8, AROB_PSEF5 ;  C3KAI3, AROB_PSEFS ;
DR   Q3IJA2, AROB_PSEHT ;  A4XPQ2, AROB_PSEMY ;  A5WAB1, AROB_PSEP1 ;
DR   Q3KJA1, AROB_PSEPF ;  Q88CV2, AROB_PSEPK ;  B1J2J5, AROB_PSEPW ;
DR   Q87V15, AROB_PSESM ;  Q4ZZE3, AROB_PSEU2 ;  A4VH14, AROB_PSEU5 ;
DR   Q4FQI3, AROB_PSYA2 ;  Q1Q8Q9, AROB_PSYCK ;  A1SRB7, AROB_PSYIN ;
DR   Q9V1H9, AROB_PYRAB ;  Q8ZW80, AROB_PYRAE ;  A3MUK4, AROB_PYRCJ ;
DR   Q8U0A8, AROB_PYRFU ;  A1RVE1, AROB_PYRIL ;  Q5JFX1, AROB_PYRKO ;
DR   Q1LI88, AROB_RALME ;  B2UEG9, AROB_RALPJ ;  Q8XV62, AROB_RALSO ;
DR   B3PPF1, AROB_RHIE6 ;  Q2K3L3, AROB_RHIEC ;  Q1MB46, AROB_RHIL3 ;
DR   Q98FY1, AROB_RHILO ;  B5ZSI4, AROB_RHILW ;  Q92ME7, AROB_RHIME ;
DR   Q7UWN8, AROB_RHOBA ;  C0ZZB6, AROB_RHOE4 ;  C1B4I1, AROB_RHOOB ;
DR   Q07VC9, AROB_RHOP5 ;  Q6NCG9, AROB_RHOPA ;  Q21BX8, AROB_RHOPB ;
DR   B3QAH7, AROB_RHOPT ;  Q2RMW0, AROB_RHORT ;  A3PJS2, AROB_RHOS1 ;
DR   Q3J2J0, AROB_RHOS4 ;  A4WSQ8, AROB_RHOS5 ;  B9KSJ9, AROB_RHOSK ;
DR   Q164J6, AROB_ROSDO ;  A1AW10, AROB_RUTMC ;  Q21H84, AROB_SACD2 ;
DR   A4FBE8, AROB_SACEN ;  B5F8K0, AROB_SALA4 ;  A9MMD9, AROB_SALAR ;
DR   Q57IY8, AROB_SALCH ;  B5FJQ9, AROB_SALDC ;  B5R2D5, AROB_SALEP ;
DR   B5R7M8, AROB_SALG2 ;  B4TKR2, AROB_SALHS ;  B4SVI8, AROB_SALNS ;
DR   Q5PLX2, AROB_SALPA ;  A9MT55, AROB_SALPB ;  C0Q0G1, AROB_SALPC ;
DR   B5BH29, AROB_SALPK ;  Q2S2D3, AROB_SALRD ;  B4TY46, AROB_SALSV ;
DR   Q8Z205, AROB_SALTI ;  P77980, AROB_SALTY ;  A8GKQ7, AROB_SERP5 ;
DR   A1SB13, AROB_SHEAM ;  B8EBF1, AROB_SHEB2 ;  A3DA14, AROB_SHEB5 ;
DR   A6WTR1, AROB_SHEB8 ;  A9L694, AROB_SHEB9 ;  Q12SL8, AROB_SHEDO ;
DR   Q088S6, AROB_SHEFN ;  B0TL76, AROB_SHEHH ;  A3Q9D8, AROB_SHELP ;
DR   Q8EK19, AROB_SHEON ;  A8GZ30, AROB_SHEPA ;  A4YBT0, AROB_SHEPC ;
DR   B8CNI9, AROB_SHEPW ;  A0L242, AROB_SHESA ;  A8G195, AROB_SHESH ;
DR   Q0HDV7, AROB_SHESM ;  Q0I052, AROB_SHESR ;  A1RPQ6, AROB_SHESW ;
DR   B1KP72, AROB_SHEWM ;  B2U3J5, AROB_SHIB3 ;  Q31VP5, AROB_SHIBS ;
DR   Q32AK1, AROB_SHIDS ;  Q0SZS9, AROB_SHIF8 ;  Q83PX0, AROB_SHIFL ;
DR   Q3YWN4, AROB_SHISS ;  Q5LSX9, AROB_SILPO ;  Q1GGQ1, AROB_SILST ;
DR   A6UCL4, AROB_SINMW ;  Q2NQJ2, AROB_SODGM ;  Q01Q15, AROB_SOLUE ;
DR   A7X2G6, AROB_STAA1 ;  A6U1T4, AROB_STAA2 ;  Q2FGX5, AROB_STAA3 ;
DR   Q2FYH0, AROB_STAA8 ;  A5ISZ5, AROB_STAA9 ;  Q2YY89, AROB_STAAB ;
DR   Q5HFV8, AROB_STAAC ;  A6QH16, AROB_STAAE ;  P63617, AROB_STAAM ;
DR   P63618, AROB_STAAN ;  Q6GGU4, AROB_STAAR ;  Q6G997, AROB_STAAS ;
DR   A8Z445, AROB_STAAT ;  Q8NWN4, AROB_STAAW ;  B9DNV1, AROB_STACT ;
DR   Q5HP78, AROB_STAEQ ;  Q8CP68, AROB_STAES ;  Q4L6G9, AROB_STAHJ ;
DR   Q49XS1, AROB_STAS1 ;  Q3K0D4, AROB_STRA1 ;  Q8E4F3, AROB_STRA3 ;
DR   Q8DYU5, AROB_STRA5 ;  Q827R8, AROB_STRAW ;  Q9KXQ6, AROB_STRCO ;
DR   C0MC29, AROB_STRE4 ;  A8AXZ4, AROB_STRGC ;  Q8DUW2, AROB_STRMU ;
DR   Q99YR3, AROB_STRP1 ;  Q04JX2, AROB_STRP2 ;  P0CZ80, AROB_STRP3 ;
DR   B5E5N3, AROB_STRP4 ;  Q5XAW2, AROB_STRP6 ;  C1C7X6, AROB_STRP7 ;
DR   Q8P036, AROB_STRP8 ;  A2RDH0, AROB_STRPG ;  B1ICH6, AROB_STRPI ;
DR   B8ZKM4, AROB_STRPJ ;  Q48S61, AROB_STRPM ;  Q97Q56, AROB_STRPN ;
DR   P0CZ81, AROB_STRPQ ;  B2IQJ3, AROB_STRPS ;  B5XME6, AROB_STRPZ ;
DR   Q8DPD1, AROB_STRR6 ;  A4W236, AROB_STRS2 ;  C0MHD7, AROB_STRS7 ;
DR   A3CNV7, AROB_STRSV ;  A4VVS9, AROB_STRSY ;  Q5M0M0, AROB_STRT1 ;
DR   Q5M556, AROB_STRT2 ;  Q03LH4, AROB_STRTD ;  C1CEW4, AROB_STRZJ ;
DR   C1CL84, AROB_STRZP ;  C1CQY0, AROB_STRZT ;  Q4JC76, AROB_SULAC ;
DR   Q30RT3, AROB_SULDN ;  A6Q908, AROB_SULNB ;  Q980I9, AROB_SULSO ;
DR   Q96Y96, AROB_SULTO ;  Q67N10, AROB_SYMTH ;  B1XKA0, AROB_SYNP2 ;
DR   Q5N3D4, AROB_SYNP6 ;  Q7U6M8, AROB_SYNPX ;  Q3AJM8, AROB_SYNSC ;
DR   P73997, AROB_SYNY3 ;  C5BRJ7, AROB_TERTT ;  Q9HLE3, AROB_THEAC ;
DR   Q8DKS3, AROB_THEEB ;  Q47QY7, AROB_THEFY ;  B1YD64, AROB_THENV ;
DR   B0K924, AROB_THEP3 ;  B0K0I7, AROB_THEPX ;  Q8RB14, AROB_THETN ;
DR   Q978S6, AROB_THEVO ;  B5YHI4, AROB_THEYD ;  Q31DP9, AROB_THICR ;
DR   Q3SLY4, AROB_THIDA ;  B8GPV3, AROB_THISH ;  C4LB07, AROB_TOLAT ;
DR   Q83HU4, AROB_TROW8 ;  Q83GD7, AROB_TROWT ;  B1GZJ4, AROB_UNCTG ;
DR   A5CX62, AROB_VESOH ;  Q9KNV2, AROB_VIBCH ;  Q5E2G0, AROB_VIBF1 ;
DR   B5FBN1, AROB_VIBFM ;  A7MSY2, AROB_VIBHB ;  Q87L68, AROB_VIBPA ;
DR   B7VLJ6, AROB_VIBSL ;  Q8DCM0, AROB_VIBVU ;  Q7MH84, AROB_VIBVY ;
DR   Q7M8N9, AROB_WOLSU ;  Q8PI87, AROB_XANAC ;  Q3BQS1, AROB_XANC5 ;
DR   Q4UX86, AROB_XANC8 ;  Q8P6X3, AROB_XANCP ;  Q2P6C9, AROB_XANOM ;
DR   B2SKP5, AROB_XANOP ;  Q5H3H4, AROB_XANOR ;  B2I9G0, AROB_XYLF2 ;
DR   Q9PDP5, AROB_XYLFA ;  B0U6C7, AROB_XYLFM ;  Q87DU9, AROB_XYLFT ;
DR   A7FNT5, AROB_YERP3 ;  Q1C2P3, AROB_YERPA ;  B2K5T4, AROB_YERPB ;
DR   Q8ZJF6, AROB_YERPE ;  A9R4A9, AROB_YERPG ;  Q1CCP0, AROB_YERPN ;
DR   A4TGU2, AROB_YERPP ;  Q664M0, AROB_YERPS ;  B1JIQ4, AROB_YERPY ;
DR   Q5NPY8, AROB_ZYMMO ;  Q8G5X4, AROKB_BIFLO;  Q9WYI3, AROKB_THEMA;
//
ID   4.2.3.5
DE   Chorismate synthase.
AN   5-enolpyruvylshikimate-3-phosphate phospholyase.
CA   5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate.
CF   FMN.
CC   -!- The reaction goes via a radical mechanism that involves reduced FMN
CC       and its semiquinone (FMNH.).
CC   -!- Shikimate is numbered so that the double-bond is between C-1 and C-2,
CC       but some earlier papers numbered the ring in the reverse direction.
CC   -!- Formerly EC 4.6.1.4.
PR   PROSITE; PDOC00628;
DR   A0RBX0, AROC1_BACAH;  Q81SV7, AROC1_BACAN;  Q73AX9, AROC1_BACC1;
DR   Q81FQ3, AROC1_BACCR;  Q63DL6, AROC1_BACCZ;  Q6HL39, AROC1_BACHK;
DR   Q42884, AROC1_SOLLC;  A0RFD4, AROC2_BACAH;  Q81P61, AROC2_BACAN;
DR   Q736A4, AROC2_BACC1;  Q81C42, AROC2_BACCR;  Q63A04, AROC2_BACCZ;
DR   Q6HHF5, AROC2_BACHK;  Q42885, AROC2_SOLLC;  B0C2W2, AROC_ACAM1 ;
DR   A1TRH4, AROC_ACIAC ;  Q6FAR2, AROC_ACIAD ;  B7H3A6, AROC_ACIB3 ;
DR   B7I5W6, AROC_ACIB5 ;  B2I0B7, AROC_ACIBC ;  Q1IIL2, AROC_ACIBL ;
DR   B0VPN2, AROC_ACIBS ;  A3M5C7, AROC_ACIBT ;  B0VDX7, AROC_ACIBY ;
DR   A0LUH1, AROC_ACIC1 ;  C1F540, AROC_ACIC5 ;  A5FY49, AROC_ACICJ ;
DR   B9MAD0, AROC_ACIET ;  B7JC67, AROC_ACIF2 ;  B5EJT1, AROC_ACIF5 ;
DR   A1W6H4, AROC_ACISJ ;  A3N0B0, AROC_ACTP2 ;  B3GXI4, AROC_ACTP7 ;
DR   B0BP27, AROC_ACTPJ ;  A6VMY7, AROC_ACTSZ ;  A0KKS7, AROC_AERHH ;
DR   Q9YEL4, AROC_AERPE ;  A4SM83, AROC_AERS4 ;  Q7D0R6, AROC_AGRT5 ;
DR   B9JSM6, AROC_AGRVS ;  B2UNJ5, AROC_AKKM8 ;  Q0VPH7, AROC_ALCBS ;
DR   Q0A9B2, AROC_ALHEH ;  A6TL06, AROC_ALKMQ ;  A8MH14, AROC_ALKOO ;
DR   B4RU03, AROC_ALTMD ;  B8J8W9, AROC_ANAD2 ;  Q2IMD4, AROC_ANADE ;
DR   A7H6S8, AROC_ANADF ;  B4ULJ3, AROC_ANASK ;  B9MRS5, AROC_ANATD ;
DR   Q3MFM3, AROC_ANAVT ;  O66493, AROC_AQUAE ;  P57720, AROC_ARATH ;
DR   A8EV89, AROC_ARCB4 ;  O29587, AROC_ARCFU ;  Q5P1K1, AROC_AROAE ;
DR   A1R705, AROC_ARTAT ;  B8H8V7, AROC_ARTCA ;  A0JX84, AROC_ARTS2 ;
DR   C8WAF3, AROC_ATOPD ;  A8I4M5, AROC_AZOC5 ;  B6YRU6, AROC_AZOPC ;
DR   A1K498, AROC_AZOSB ;  A7Z623, AROC_BACA2 ;  A7GN53, AROC_BACCN ;
DR   Q5L9G0, AROC_BACFN ;  Q64PP7, AROC_BACFR ;  Q9KCB7, AROC_BACHD ;
DR   Q65I28, AROC_BACLD ;  A8FEK5, AROC_BACP2 ;  Q5WGS8, AROC_BACSK ;
DR   P31104, AROC_BACSU ;  Q8A602, AROC_BACTN ;  A6L3D0, AROC_BACV8 ;
DR   A1URW3, AROC_BARBK ;  Q6G4D4, AROC_BARHE ;  Q6G0D7, AROC_BARQU ;
DR   A9IQN4, AROC_BART1 ;  Q1LTA9, AROC_BAUCH ;  Q6MHP7, AROC_BDEBA ;
DR   B2IDQ8, AROC_BEII9 ;  C5C5T3, AROC_BEUC1 ;  B8DUQ4, AROC_BIFA0 ;
DR   A1A1A2, AROC_BIFAA ;  B3DSD9, AROC_BIFLD ;  Q8G5X3, AROC_BIFLO ;
DR   B7GS97, AROC_BIFLS ;  Q7VRU6, AROC_BLOFL ;  Q492G9, AROC_BLOPB ;
DR   Q2KYK7, AROC_BORA1 ;  Q7WKJ5, AROC_BORBR ;  Q7W950, AROC_BORPA ;
DR   A9IT47, AROC_BORPD ;  Q7VY92, AROC_BORPE ;  Q89RY1, AROC_BRAJA ;
DR   A5EEP1, AROC_BRASB ;  A4YQ28, AROC_BRASO ;  C0ZCD8, AROC_BREBN ;
DR   B2S9R7, AROC_BRUA1 ;  Q2YMF8, AROC_BRUA2 ;  Q57ET8, AROC_BRUAB ;
DR   A9M8V2, AROC_BRUC2 ;  C0RHD5, AROC_BRUMB ;  P63607, AROC_BRUME ;
DR   A5VP02, AROC_BRUO2 ;  B0CKB2, AROC_BRUSI ;  P63608, AROC_BRUSU ;
DR   B8D8P9, AROC_BUCA5 ;  P57198, AROC_BUCAI ;  Q9ZHE9, AROC_BUCAP ;
DR   B8D703, AROC_BUCAT ;  Q89AX9, AROC_BUCBP ;  Q058B0, AROC_BUCCC ;
DR   B1YNZ5, AROC_BURA4 ;  Q1BWW8, AROC_BURCA ;  B1K077, AROC_BURCC ;
DR   A0K6T5, AROC_BURCH ;  B4E7H2, AROC_BURCJ ;  Q0BG24, AROC_BURCM ;
DR   A9ABG9, AROC_BURM1 ;  A3MJ92, AROC_BURM7 ;  A2S381, AROC_BURM9 ;
DR   Q62KU7, AROC_BURMA ;  A1V3K9, AROC_BURMS ;  A3NUG3, AROC_BURP0 ;
DR   Q3JT35, AROC_BURP1 ;  A3N8Q9, AROC_BURP6 ;  B2JK28, AROC_BURP8 ;
DR   B2SZH3, AROC_BURPP ;  Q63TK6, AROC_BURPS ;  Q39H65, AROC_BURS3 ;
DR   Q2SVC0, AROC_BURTA ;  A4JDS6, AROC_BURVG ;  Q13WE6, AROC_BURXL ;
DR   A8MC69, AROC_CALMQ ;  A4XKJ4, AROC_CALS8 ;  A8Z6F5, AROC_CAMC1 ;
DR   A7H187, AROC_CAMC5 ;  A0RRM6, AROC_CAMFF ;  A7HZN6, AROC_CAMHC ;
DR   A8FNU6, AROC_CAMJ8 ;  A7H5Y1, AROC_CAMJD ;  Q9PM41, AROC_CAMJE ;
DR   A1W1N6, AROC_CAMJJ ;  Q5HSF9, AROC_CAMJR ;  B9KE09, AROC_CAMLR ;
DR   Q3AEF4, AROC_CARHZ ;  Q05FR1, AROC_CARRP ;  B8H3W7, AROC_CAUCN ;
DR   Q9A3P8, AROC_CAUCR ;  B3PHF4, AROC_CELJU ;  C7PC56, AROC_CHIPD ;
DR   A9WI34, AROC_CHLAA ;  Q5L5F2, AROC_CHLAB ;  B8GB37, AROC_CHLAD ;
DR   Q3AQF1, AROC_CHLCH ;  Q822F8, AROC_CHLCV ;  Q255H5, AROC_CHLFF ;
DR   B3EID0, AROC_CHLL2 ;  Q9PK26, AROC_CHLMU ;  B3QMJ7, AROC_CHLP8 ;
DR   B3EPI9, AROC_CHLPB ;  A1BHE5, AROC_CHLPD ;  Q9Z6M2, AROC_CHLPN ;
DR   B9LK59, AROC_CHLSY ;  B0B7T7, AROC_CHLT2 ;  B3QWJ0, AROC_CHLT3 ;
DR   Q3KLY8, AROC_CHLTA ;  B0BC02, AROC_CHLTB ;  Q8KCI9, AROC_CHLTE ;
DR   O84373, AROC_CHLTR ;  Q1QUP5, AROC_CHRSD ;  Q7NYT5, AROC_CHRVO ;
DR   A8ADP9, AROC_CITK8 ;  A5CRZ1, AROC_CLAM3 ;  A9KQX0, AROC_CLOPH ;
DR   E3PV41, AROC_CLOSD ;  Q892J3, AROC_CLOTE ;  A3DDD8, AROC_CLOTH ;
DR   Q47ZC3, AROC_COLP3 ;  C3PGM7, AROC_CORA7 ;  Q6NH02, AROC_CORDI ;
DR   Q8FT29, AROC_COREF ;  A4QEJ8, AROC_CORGB ;  Q9X5D0, AROC_CORGL ;
DR   Q4JVG0, AROC_CORJK ;  P27793, AROC_CORSE ;  Q83D67, AROC_COXBU ;
DR   Q0KC14, AROC_CUPNH ;  Q472Q5, AROC_CUPPJ ;  B1WRV7, AROC_CYAA5 ;
DR   B8HNK4, AROC_CYAP4 ;  B7KIU0, AROC_CYAP7 ;  B7JVZ9, AROC_CYAP8 ;
DR   Q11Y57, AROC_CYTH3 ;  Q47HR7, AROC_DECAR ;  Q3Z993, AROC_DEHE1 ;
DR   A5FS06, AROC_DEHSB ;  Q3ZZI6, AROC_DEHSC ;  Q1IXK9, AROC_DEIGD ;
DR   Q9RW94, AROC_DEIRA ;  B8FFQ6, AROC_DESAA ;  C6C0I6, AROC_DESAD ;
DR   B1I3D5, AROC_DESAP ;  B8J4Q3, AROC_DESDA ;  Q30XS4, AROC_DESDG ;
DR   B8FQ92, AROC_DESHD ;  Q24UW1, AROC_DESHY ;  A8ZT68, AROC_DESOH ;
DR   Q6AIP3, AROC_DESPS ;  A4J3A1, AROC_DESRM ;  Q72DN5, AROC_DESVH ;
DR   B8DRR9, AROC_DESVM ;  A1VF90, AROC_DESVV ;  A5EXT0, AROC_DICNV ;
DR   A8LMT3, AROC_DINSH ;  A7ZPE5, AROC_ECO24 ;  B7UFY7, AROC_ECO27 ;
DR   B7MG93, AROC_ECO45 ;  B7LBI3, AROC_ECO55 ;  P63610, AROC_ECO57 ;
DR   B5YXX0, AROC_ECO5E ;  B7NP10, AROC_ECO7I ;  B7MY06, AROC_ECO81 ;
DR   B7M6L0, AROC_ECO8A ;  C4ZVM2, AROC_ECOBW ;  B1X9K2, AROC_ECODH ;
DR   A8A2J9, AROC_ECOHS ;  A1ADH8, AROC_ECOK1 ;  Q0TFB7, AROC_ECOL5 ;
DR   P63609, AROC_ECOL6 ;  B1IXB6, AROC_ECOLC ;  P12008, AROC_ECOLI ;
DR   B7N5U1, AROC_ECOLU ;  B6I4X6, AROC_ECOSE ;  B1LLT5, AROC_ECOSM ;
DR   Q1R983, AROC_ECOUT ;  C5BAF2, AROC_EDWI9 ;  A4WCW2, AROC_ENT38 ;
DR   Q834S2, AROC_ENTFA ;  A7MH70, AROC_ENTS8 ;  Q6D2M6, AROC_ERWCT ;
DR   B2VIY1, AROC_ERWT9 ;  Q2N810, AROC_ERYLH ;  B7LLE1, AROC_ESCF3 ;
DR   C4Z562, AROC_EUBE2 ;  C4ZAX1, AROC_EUBR3 ;  B1YI20, AROC_EXIS2 ;
DR   C4L6N3, AROC_EXISA ;  A5FB38, AROC_FLAJ1 ;  A6GXP5, AROC_FLAPJ ;
DR   Q0RF70, AROC_FRAAA ;  Q2J826, AROC_FRASC ;  A8LE02, AROC_FRASN ;
DR   Q14HW8, AROC_FRAT1 ;  A7NA74, AROC_FRATF ;  Q2A549, AROC_FRATH ;
DR   B2SF54, AROC_FRATM ;  A0Q4Z0, AROC_FRATN ;  Q0BNG4, AROC_FRATO ;
DR   Q5NGG6, AROC_FRATT ;  A4IYS7, AROC_FRATW ;  Q5KXU4, AROC_GEOKA ;
DR   B3E9N0, AROC_GEOLS ;  Q39X06, AROC_GEOMG ;  B9M3I5, AROC_GEOSF ;
DR   Q74BL4, AROC_GEOSL ;  C5D3E1, AROC_GEOSW ;  A4IQ89, AROC_GEOTN ;
DR   A5GF03, AROC_GEOUR ;  Q7NFY1, AROC_GLOVI ;  A9H0U2, AROC_GLUDA ;
DR   Q5FPG9, AROC_GLUOX ;  Q0BVN0, AROC_GRABC ;  A0M1V5, AROC_GRAFK ;
DR   Q7VLX2, AROC_HAEDU ;  Q4QNZ4, AROC_HAEI8 ;  A5UAV8, AROC_HAEIE ;
DR   A5UFZ9, AROC_HAEIG ;  P43875, AROC_HAEIN ;  B8F415, AROC_HAEPS ;
DR   Q0I3U1, AROC_HAES1 ;  B0UWQ4, AROC_HAES2 ;  Q2SJE4, AROC_HAHCH ;
DR   A1WY16, AROC_HALHL ;  B9LMX0, AROC_HALLT ;  Q5V5K5, AROC_HALMA ;
DR   C7NZH8, AROC_HALMD ;  Q9HQC2, AROC_HALSA ;  Q18F10, AROC_HALWD ;
DR   C4K3S0, AROC_HAMD5 ;  Q17XJ5, AROC_HELAH ;  Q7VIA8, AROC_HELHP ;
DR   B6JLQ1, AROC_HELP2 ;  B5Z736, AROC_HELPG ;  Q1CTK7, AROC_HELPH ;
DR   Q9ZLH1, AROC_HELPJ ;  B2UTG3, AROC_HELPS ;  P56122, AROC_HELPY ;
DR   A9AWF4, AROC_HERA2 ;  A4G4F3, AROC_HERAR ;  Q0C3Z3, AROC_HYPNA ;
DR   Q5QW40, AROC_IDILO ;  A8A9W1, AROC_IGNH4 ;  A6T017, AROC_JANMA ;
DR   Q28VL4, AROC_JANSC ;  B5XVW6, AROC_KLEP3 ;  A6TC15, AROC_KLEP7 ;
DR   B2GI97, AROC_KOCRD ;  B1L5G9, AROC_KORCO ;  B2GCR2, AROC_LACF3 ;
DR   Q9CET2, AROC_LACLA ;  A2RMH2, AROC_LACLM ;  Q02XC2, AROC_LACLS ;
DR   Q88VL0, AROC_LACPL ;  C1DBU8, AROC_LARHH ;  Q5X2Y6, AROC_LEGPA ;
DR   A5IEA1, AROC_LEGPC ;  Q5ZT62, AROC_LEGPH ;  Q5WUE6, AROC_LEGPL ;
DR   Q6AF97, AROC_LEIXX ;  B0SHV8, AROC_LEPBA ;  Q04W40, AROC_LEPBJ ;
DR   Q04XD2, AROC_LEPBL ;  B0SRH8, AROC_LEPBP ;  B1XWC5, AROC_LEPCP ;
DR   Q72W01, AROC_LEPIC ;  Q8F9N4, AROC_LEPIN ;  B1MYD0, AROC_LEUCK ;
DR   Q03X09, AROC_LEUMM ;  Q92A80, AROC_LISIN ;  C1KWM8, AROC_LISMC ;
DR   Q71Y87, AROC_LISMF ;  B8DBZ8, AROC_LISMH ;  Q8Y5X5, AROC_LISMO ;
DR   A0AK40, AROC_LISW6 ;  B1HTD1, AROC_LYSSC ;  Q2W6Y1, AROC_MAGSA ;
DR   A0LDR1, AROC_MAGSM ;  Q65U87, AROC_MANSM ;  A1U0Y3, AROC_MARAV ;
DR   Q0ARD9, AROC_MARMM ;  A6VXI7, AROC_MARMS ;  Q11KE5, AROC_MESSB ;
DR   A6UUV1, AROC_META3 ;  Q8TT87, AROC_METAC ;  Q46CJ6, AROC_METBF ;
DR   Q12X75, AROC_METBU ;  B7KT24, AROC_METC4 ;  Q60AY5, AROC_METCA ;
DR   A9W6U7, AROC_METEP ;  Q1GZD3, AROC_METFK ;  B3DXL0, AROC_METI4 ;
DR   Q58575, AROC_METJA ;  Q8TXN1, AROC_METKA ;  A4FWK1, AROC_METM5 ;
DR   A6VGS0, AROC_METM7 ;  Q8PW84, AROC_METMA ;  Q6LXL7, AROC_METMP ;
DR   B8IS51, AROC_METNO ;  B1ZHL0, AROC_METPB ;  A2SFP8, AROC_METPP ;
DR   B1M325, AROC_METRJ ;  A5UNA1, AROC_METS3 ;  B0UJB1, AROC_METS4 ;
DR   A4YHW1, AROC_METS5 ;  B8ESC6, AROC_METSB ;  Q2NGS6, AROC_METST ;
DR   O26843, AROC_METTH ;  A0B5I7, AROC_METTP ;  A6UPX8, AROC_METVS ;
DR   B0JWQ2, AROC_MICAN ;  C5CCG1, AROC_MICLC ;  Q2RI73, AROC_MOOTA ;
DR   A0QI61, AROC_MYCA1 ;  B1MCF1, AROC_MYCA9 ;  P63612, AROC_MYCBO ;
DR   A1KLN7, AROC_MYCBP ;  C1AF08, AROC_MYCBT ;  B8ZUK0, AROC_MYCLB ;
DR   Q9CCS6, AROC_MYCLE ;  B2HNC6, AROC_MYCMM ;  Q741J9, AROC_MYCPA ;
DR   A0QWQ9, AROC_MYCS2 ;  A3PZ50, AROC_MYCSJ ;  A1UFI9, AROC_MYCSK ;
DR   Q1B9H4, AROC_MYCSS ;  A5U5N9, AROC_MYCTA ;  P63611, AROC_MYCTU ;
DR   A0PPH0, AROC_MYCUA ;  A1T8F3, AROC_MYCVP ;  Q5F756, AROC_NEIG1 ;
DR   B4RN46, AROC_NEIG2 ;  A9M1Q2, AROC_NEIM0 ;  Q9JT81, AROC_NEIMA ;
DR   Q9JY99, AROC_NEIMB ;  A1KV89, AROC_NEIMF ;  Q12640, AROC_NEUCR ;
DR   Q0AEP5, AROC_NITEC ;  Q82TK9, AROC_NITEU ;  Q1QQ46, AROC_NITHX ;
DR   Q2Y7L8, AROC_NITMU ;  Q3J713, AROC_NITOC ;  A6Q1H1, AROC_NITSB ;
DR   Q3SUZ5, AROC_NITWN ;  Q5YTK8, AROC_NOCFA ;  A1SJD2, AROC_NOCSJ ;
DR   B2J1W7, AROC_NOSP7 ;  Q8YYP9, AROC_NOSS1 ;  Q2GCF2, AROC_NOVAD ;
DR   Q8EQB6, AROC_OCEIH ;  A6WWB6, AROC_OCHA4 ;  B6JFJ0, AROC_OLICO ;
DR   B1ZUM3, AROC_OPITP ;  A6LDP9, AROC_PARD8 ;  A1BA52, AROC_PARDP ;
DR   A7HR75, AROC_PARL1 ;  Q6MCU1, AROC_PARUW ;  P57840, AROC_PASMU ;
DR   C6DA85, AROC_PECCP ;  Q3A2N5, AROC_PELCD ;  Q3B2Y6, AROC_PELLD ;
DR   B4SFH4, AROC_PELPB ;  A1AQL6, AROC_PELPD ;  A5D372, AROC_PELTS ;
DR   Q4FN06, AROC_PELUB ;  B4RHV8, AROC_PHEZH ;  Q7N299, AROC_PHOLL ;
DR   Q6LNN4, AROC_PHOPR ;  A1VQW9, AROC_POLNA ;  B1XUP3, AROC_POLNS ;
DR   Q12CG7, AROC_POLSJ ;  A4SXH9, AROC_POLSQ ;  Q7MV04, AROC_PORGI ;
DR   B4S930, AROC_PROA2 ;  Q6A8I4, AROC_PROAC ;  A3PAU4, AROC_PROM0 ;
DR   A2C058, AROC_PROM1 ;  A8G2N2, AROC_PROM2 ;  A2CCA2, AROC_PROM3 ;
DR   A9BDJ2, AROC_PROM4 ;  A2BUK4, AROC_PROM5 ;  Q31CV7, AROC_PROM9 ;
DR   P46894, AROC_PROMA ;  B4EZG9, AROC_PROMH ;  Q7V4Y9, AROC_PROMM ;
DR   Q7V364, AROC_PROMP ;  A2BP22, AROC_PROMS ;  Q46HE7, AROC_PROMT ;
DR   A4SFK6, AROC_PROVI ;  Q48KN0, AROC_PSE14 ;  Q15VM5, AROC_PSEA6 ;
DR   A6V7B0, AROC_PSEA7 ;  B7UV40, AROC_PSEA8 ;  Q02KH1, AROC_PSEAB ;
DR   Q9I344, AROC_PSEAE ;  Q1ID65, AROC_PSEE4 ;  Q4K8J3, AROC_PSEF5 ;
DR   C3K084, AROC_PSEFS ;  Q3IJ50, AROC_PSEHT ;  A4XTH9, AROC_PSEMY ;
DR   A5W794, AROC_PSEP1 ;  Q3KFJ1, AROC_PSEPF ;  B0KUL0, AROC_PSEPG ;
DR   Q88LU7, AROC_PSEPK ;  B1J4S1, AROC_PSEPW ;  Q884P5, AROC_PSESM ;
DR   Q4ZVC2, AROC_PSEU2 ;  A4VM84, AROC_PSEU5 ;  Q4FRQ5, AROC_PSYA2 ;
DR   Q1QA91, AROC_PSYCK ;  A1STP2, AROC_PSYIN ;  A5WDY8, AROC_PSYWF ;
DR   Q9V1H0, AROC_PYRAB ;  Q8ZW90, AROC_PYRAE ;  A4WMP8, AROC_PYRAR ;
DR   A3MUI8, AROC_PYRCJ ;  A1RVD1, AROC_PYRIL ;  Q5JFT4, AROC_PYRKO ;
DR   Q1LPA2, AROC_RALME ;  B2UGK8, AROC_RALPJ ;  Q8XZ40, AROC_RALSO ;
DR   B3PS94, AROC_RHIE6 ;  Q2KBP0, AROC_RHIEC ;  Q1MKK1, AROC_RHIL3 ;
DR   Q985Z4, AROC_RHILO ;  B5ZST4, AROC_RHILW ;  Q92RH3, AROC_RHIME ;
DR   C3MHI8, AROC_RHISN ;  Q7UPN5, AROC_RHOBA ;  B6IRC6, AROC_RHOCS ;
DR   Q21TN3, AROC_RHOFD ;  C1B4H9, AROC_RHOOB ;  Q2J0T8, AROC_RHOP2 ;
DR   Q07HS5, AROC_RHOP5 ;  Q6NAI4, AROC_RHOPA ;  Q21A81, AROC_RHOPB ;
DR   Q13BI7, AROC_RHOPS ;  B3QIL0, AROC_RHOPT ;  Q2RR25, AROC_RHORT ;
DR   A3PFR1, AROC_RHOS1 ;  Q3IY15, AROC_RHOS4 ;  A4WWC0, AROC_RHOS5 ;
DR   B9KQP8, AROC_RHOSK ;  Q0S0N2, AROC_RHOSR ;  A7NQM2, AROC_ROSCS ;
DR   Q16CN2, AROC_ROSDO ;  A5UUN7, AROC_ROSS1 ;  Q1AW05, AROC_RUBXD ;
DR   A1AW83, AROC_RUTMC ;  Q21IX8, AROC_SACD2 ;  A4FBE6, AROC_SACEN ;
DR   B5EZR6, AROC_SALA4 ;  A9MJ42, AROC_SALAR ;  Q57LX0, AROC_SALCH ;
DR   B5FPM7, AROC_SALDC ;  B5R3R5, AROC_SALEP ;  B5RCK9, AROC_SALG2 ;
DR   B4TCA5, AROC_SALHS ;  B4SZQ7, AROC_SALNS ;  Q5PCX2, AROC_SALPA ;
DR   A9N460, AROC_SALPB ;  B5BBA5, AROC_SALPK ;  Q2S0W2, AROC_SALRD ;
DR   B4TQB9, AROC_SALSV ;  P16280, AROC_SALTI ;  A4X607, AROC_SALTO ;
DR   P58729, AROC_SALTY ;  O74413, AROC_SCHPO ;  A8GH82, AROC_SERP5 ;
DR   A1S7K8, AROC_SHEAM ;  B8EEA7, AROC_SHEB2 ;  A3D676, AROC_SHEB5 ;
DR   A6WQ14, AROC_SHEB8 ;  A9KTV7, AROC_SHEB9 ;  Q12P04, AROC_SHEDO ;
DR   Q07ZQ7, AROC_SHEFN ;  A3QFN4, AROC_SHELP ;  A4Y889, AROC_SHEPC ;
DR   A0KV84, AROC_SHESA ;  A8FTS6, AROC_SHESH ;  Q0HKC3, AROC_SHESM ;
DR   Q0HWM5, AROC_SHESR ;  A1RIA0, AROC_SHESW ;  B1KKS1, AROC_SHEWM ;
DR   B2TWB1, AROC_SHIB3 ;  Q31YC9, AROC_SHIBS ;  Q32DK8, AROC_SHIDS ;
DR   Q0T2F6, AROC_SHIF8 ;  Q83QQ5, AROC_SHIFL ;  Q3YZN2, AROC_SHISS ;
DR   Q5LX60, AROC_SILPO ;  Q1GCR5, AROC_SILST ;  A6U6U1, AROC_SINMW ;
DR   Q2NSH3, AROC_SODGM ;  Q023V7, AROC_SOLUE ;  Q1GVE2, AROC_SPHAL ;
DR   A5VFP1, AROC_SPHWW ;  A7X2G8, AROC_STAA1 ;  A6U1T5, AROC_STAA2 ;
DR   Q2FGX4, AROC_STAA3 ;  Q2FYG9, AROC_STAA8 ;  A5ISZ6, AROC_STAA9 ;
DR   Q2YY88, AROC_STAAB ;  Q5HFV7, AROC_STAAC ;  A6QH17, AROC_STAAE ;
DR   P63613, AROC_STAAM ;  P63614, AROC_STAAN ;  Q6GGU3, AROC_STAAR ;
DR   Q6G996, AROC_STAAS ;  A8Z446, AROC_STAAT ;  Q59803, AROC_STAAU ;
DR   Q8NWN3, AROC_STAAW ;  B9DNV2, AROC_STACT ;  Q5HP77, AROC_STAEQ ;
DR   Q8CP67, AROC_STAES ;  Q4L6H0, AROC_STAHJ ;  Q49XS2, AROC_STAS1 ;
DR   Q3K0D5, AROC_STRA1 ;  Q8E4F4, AROC_STRA3 ;  Q8DYU6, AROC_STRA5 ;
DR   Q827S0, AROC_STRAW ;  Q9KXQ4, AROC_STRCO ;  C0M8T9, AROC_STRE4 ;
DR   B4U2K7, AROC_STREM ;  B4SQW1, AROC_STRM5 ;  B2FP01, AROC_STRMK ;
DR   Q8DUW1, AROC_STRMU ;  Q9A0E4, AROC_STRP1 ;  Q04JX3, AROC_STRP2 ;
DR   P0CZ78, AROC_STRP3 ;  B5E5N2, AROC_STRP4 ;  Q5XCT6, AROC_STRP6 ;
DR   C1C7X5, AROC_STRP7 ;  Q8P1H5, AROC_STRP8 ;  Q1JCG6, AROC_STRPB ;
DR   Q1JME4, AROC_STRPC ;  Q1JHJ1, AROC_STRPD ;  Q1J7B2, AROC_STRPF ;
DR   A2RF78, AROC_STRPG ;  B1ICH5, AROC_STRPI ;  B8ZKM3, AROC_STRPJ ;
DR   Q48U88, AROC_STRPM ;  P0A2Y6, AROC_STRPN ;  P0CZ79, AROC_STRPQ ;
DR   B2IQJ2, AROC_STRPS ;  B5XKU4, AROC_STRPZ ;  P0A2Y7, AROC_STRR6 ;
DR   A4W246, AROC_STRS2 ;  C0MGL3, AROC_STRS7 ;  A3CNV6, AROC_STRSV ;
DR   A4VVT9, AROC_STRSY ;  Q5M0L9, AROC_STRT1 ;  Q5M555, AROC_STRT2 ;
DR   Q03LH3, AROC_STRTD ;  B9DU46, AROC_STRU0 ;  C1CEW3, AROC_STRZJ ;
DR   C1CL83, AROC_STRZP ;  C1CQY1, AROC_STRZT ;  Q4JC74, AROC_SULAC ;
DR   Q30NY4, AROC_SULDN ;  C3MZF2, AROC_SULIA ;  C4KIN2, AROC_SULIK ;
DR   C3MRB7, AROC_SULIL ;  C3MXK6, AROC_SULIM ;  C3NG02, AROC_SULIN ;
DR   C3N7H4, AROC_SULIY ;  A8Z5Z2, AROC_SULMW ;  A6QCJ1, AROC_SULNB ;
DR   Q980I7, AROC_SULSO ;  B2V7C0, AROC_SULSY ;  Q96Y94, AROC_SULTO ;
DR   Q67N08, AROC_SYMTH ;  Q2LUC8, AROC_SYNAS ;  Q31RS5, AROC_SYNE7 ;
DR   A0LE92, AROC_SYNFM ;  Q2JXD0, AROC_SYNJA ;  Q2JLD4, AROC_SYNJB ;
DR   B1XIM6, AROC_SYNP2 ;  Q5N2I0, AROC_SYNP6 ;  A5GIL9, AROC_SYNPW ;
DR   Q7U9F0, AROC_SYNPX ;  A5GW34, AROC_SYNR3 ;  Q0ID82, AROC_SYNS3 ;
DR   Q3AUR6, AROC_SYNS9 ;  Q3AMV2, AROC_SYNSC ;  Q0AZJ3, AROC_SYNWW ;
DR   P23353, AROC_SYNY3 ;  C5BL71, AROC_TERTT ;  Q9HJY7, AROC_THEAC ;
DR   Q8DLM1, AROC_THEEB ;  Q47QY9, AROC_THEFY ;  C5A782, AROC_THEGJ ;
DR   Q9WYI2, AROC_THEMA ;  B1YD56, AROC_THENV ;  B0K8B2, AROC_THEP3 ;
DR   B0K3V6, AROC_THEPX ;  B1L9E3, AROC_THESQ ;  Q72IW3, AROC_THET2 ;
DR   Q5SII5, AROC_THET8 ;  Q8R9A6, AROC_THETN ;  Q97AR9, AROC_THEVO ;
DR   Q31FE3, AROC_THICR ;  Q3SL02, AROC_THIDA ;  C4L8D2, AROC_TOLAT ;
DR   O02607, AROC_TOXGO ;  Q73NM0, AROC_TREDE ;  Q110N5, AROC_TRIEI ;
DR   Q83HU6, AROC_TROW8 ;  Q83GD5, AROC_TROWT ;  Q0W6Q8, AROC_UNCMA ;
DR   B1GZT3, AROC_UNCTG ;  C5CS25, AROC_VARPS ;  A1WL18, AROC_VEREI ;
DR   A5CX05, AROC_VESOH ;  P39198, AROC_VIBAN ;  A5F6F4, AROC_VIBC3 ;
DR   Q9KQ85, AROC_VIBCH ;  C3LP65, AROC_VIBCM ;  Q5E3U6, AROC_VIBF1 ;
DR   B5FGA8, AROC_VIBFM ;  A7MS71, AROC_VIBHB ;  Q87MM9, AROC_VIBPA ;
DR   Q8DB42, AROC_VIBVU ;  Q7MIT1, AROC_VIBVY ;  Q7M841, AROC_WOLSU ;
DR   Q8PJ20, AROC_XANAC ;  Q3BRK5, AROC_XANC5 ;  Q4UWE0, AROC_XANC8 ;
DR   B0RR76, AROC_XANCB ;  Q8P7R0, AROC_XANCP ;  Q2P0T3, AROC_XANOM ;
DR   B2SVP7, AROC_XANOP ;  Q5GXQ6, AROC_XANOR ;  A7IMW7, AROC_XANP2 ;
DR   B2I9I6, AROC_XYLF2 ;  Q9PDL0, AROC_XYLFA ;  B0U6K0, AROC_XYLFM ;
DR   Q87DS4, AROC_XYLFT ;  P28777, AROC_YEAST ;  A1JK48, AROC_YERE8 ;
DR   A7FGK6, AROC_YERP3 ;  Q1C664, AROC_YERPA ;  B2K8I9, AROC_YERPB ;
DR   Q8ZD41, AROC_YERPE ;  A9R7W3, AROC_YERPG ;  Q1CHK6, AROC_YERPN ;
DR   A4TM78, AROC_YERPP ;  Q668V5, AROC_YERPS ;  B1JGG7, AROC_YERPY ;
DR   E0TIQ1, AROC_ZINIC ;  Q5NLU3, AROC_ZYMMO ;
//
ID   4.2.3.6
DE   Trichodiene synthase.
AN   Sesquiterpene cyclase.
AN   Trichodiene synthetase.
CA   Trans,trans-farnesyl diphosphate = trichodiene + diphosphate.
CC   -!- Formerly EC 4.1.99.6.
DR   Q7LJR6, TRI5_FUSAC ;  Q8NIH6, TRI5_FUSAS ;  Q8NIH0, TRI5_FUSAU ;
DR   Q8NIH3, TRI5_FUSBO ;  Q8NIC1, TRI5_FUSCE ;  Q7LJF8, TRI5_FUSCO ;
DR   Q8NIG9, TRI5_FUSCU ;  Q8NIC8, TRI5_FUSME ;  Q8NJA1, TRI5_FUSMI ;
DR   Q00835, TRI5_FUSPO ;  Q8NID7, TRI5_FUSPS ;  P13513, TRI5_FUSSP ;
DR   P27679, TRI5_GIBPU ;  Q00909, TRI5_GIBZE ;  O13489, TRI5_MYRRO ;
DR   O59947, TRI5_STACH ;  Q6A1B7, TRI5_TRIHA ;
//
ID   4.2.3.7
DE   Pentalenene synthase.
AN   Pentalenene synthetase.
CA   2-trans,6-trans-farnesyl diphosphate = pentalenene + diphosphate.
CC   -!- The initial step in the reaction is probably a cyclization of
CC       farnesyl diphosphate to form humulene.
CC   -!- Involved in the biosynthesis of pentalenolactone and related
CC       antibiotics.
CC   -!- Formerly EC 4.6.1.5.
DR   Q55012, PTLS_STRS3 ;
//
ID   4.2.3.8
DE   Casbene synthase.
AN   Casbene synthetase.
CA   Geranylgeranyl diphosphate = casbene + diphosphate.
CC   -!- The enzyme from castor bean (Ricinus communis) produces the
CC       antifungal diterpene casbene.
CC   -!- Formerly EC 4.6.1.7.
DR   P59287, CASS_RICCO ;
//
ID   4.2.3.9
DE   Aristolochene synthase.
AN   Sesquiterpene cyclase.
AN   Trans,trans-farnesyl diphosphate aristolochene-lyase.
CA   2-trans,6-trans-farnesyl diphosphate = aristolochene + diphosphate.
CF   Magnesium; Manganese.
CC   -!- The initial internal cyclization produces the monocyclic intermediate
CC       germacrene A; further cyclization and methyl transfer converts the
CC       intermediate into aristolochene.
CC   -!- While in some species germacrene A remains as an enzyme-bound
CC       intermediate, it has been shown to be a minor product of the reaction
CC       in Penicillium roqueforti (see also EC 4.2.3.23).
CC   -!- Aristolochene is the likely parent compound for a number of
CC       sesquiterpenes produced by filamentous fungi.
CC   -!- Formerly EC 2.5.1.40 and EC 4.1.99.7.
DR   Q03471, ARIS_PENRO ;
//
ID   4.2.3.10
DE   (-)-endo-fenchol synthase.
CA   Geranyl diphosphate = (-)-endo-fenchol + diphosphate.
CC   -!- (3R)-linalyl diphosphate is an intermediate in the reaction.
CC   -!- Formerly EC 4.6.1.8.
DR   Q5SBP2, FES_OCIBA  ;
//
ID   4.2.3.11
DE   Sabinene-hydrate synthase.
AN   Sabinene hydrate cyclase.
CA   Geranyl diphosphate + H(2)O = sabinene hydrate + diphosphate.
CC   -!- Both cis- and trans- isomers of sabinene hydrate are formed.
CC   -!- (3R)-linalyl diphosphate is an intermediate in the reaction.
CC   -!- Formerly EC 4.6.1.9.
DR   O81193, SSS_SALOF  ;
//
ID   4.2.3.12
DE   6-pyruvoyltetrahydropterin synthase.
AN   6-pyruvoyl tetrahydrobiopterin synthase.
AN   PTPS.
CA   7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-
CA   tetrahydropterin + triphosphate.
CF   Magnesium.
CC   -!- Catalyzes triphosphate elimination and an intramolecular redox
CC       reaction.
CC   -!- The product is 6-pyruvoyltetrahydrobiopterin.
CC   -!- Involved in the de novo synthesis of tetrahydrobiopterin from GTP,
CC       with the other enzymes involved being EC 1.1.1.153 and EC 3.5.4.16.
CC   -!- Formerly EC 4.6.1.10.
PR   PROSITE; PDOC00759;
DR   O02058, PTPS_CAEEL ;  Q1ZXI0, PTPS_DICDI ;  P48611, PTPS_DROME ;
DR   Q03393, PTPS_HUMAN ;  Q9R1Z7, PTPS_MOUSE ;  Q90W95, PTPS_POERE ;
DR   Q5REZ5, PTPS_PONAB ;  P27213, PTPS_RAT   ;  P80081, PTPS_SALSA ;
//
ID   4.2.3.13
DE   (+)-delta-cadinene synthase.
AN   D-cadinene synthase.
CA   2-trans,6-trans-farnesyl diphosphate = (+)-delta-cadinene + diphosphate.
CF   Magnesium.
CC   -!- The sesquiterpenoid (+)-delta-cadinene is an intermediate in
CC       phytoalexin biosynthesis.
CC   -!- Formerly EC 4.6.1.11.
DR   Q39761, DCS1_GOSAR ;  P93665, DCS1_GOSHI ;  Q39760, DCS2_GOSAR ;
DR   Q43714, DCS3_GOSAR ;  O49853, DCS4_GOSAR ;
//
ID   4.2.3.14
DE   Pinene synthase.
AN   (-)-(1S,5S)-pinene synthase.
AN   Beta-geraniolene synthase.
CA   (1) Geranyl diphosphate = alpha-pinene + diphosphate.
CA   (2) Geranyl diphosphate = beta-pinene + diphosphate.
CF   Manganese; Potassium.
CC   -!- Mg(2+) is essentially ineffective as the divalent metal ion cofactor.
CC   -!- A mixture of alpha and beta-pinene is produced.
CC   -!- Formerly EC 4.1.99.8.
DR   O23945, PINS_FRAVE ;  A7IZZ2, TPS2_CANSA ;  Q6XDB5, TPSD2_PICSI;
DR   O24475, TPSD3_ABIGR;
//
ID   4.2.3.15
DE   Myrcene synthase.
CA   Geranyl diphosphate = myrcene + diphosphate.
CF   Manganese; Potassium.
CC   -!- Mg(2+) is essentially ineffective as the divalent metal ion cofactor.
CC   -!- Formerly EC 4.1.99.9.
DR   Q9ZUH4, MYRS1_ARATH;  Q9LRZ6, MYRS2_ARATH;  Q5SBP1, MYRS_OCIBA ;
DR   Q93X23, MYRS_QUEIL ;  O24474, TPSD2_ABIGR;
//
ID   4.2.3.16
DE   (4S)-limonene synthase.
AN   (-)-(4S)-limonene synthase.
AN   4S-(-)-limonene synthase.
CA   Geranyl diphosphate = (-)-(4S)-limonene + diphosphate.
CF   Manganese; Potassium.
CC   -!- Mg(2+) is essentially ineffective as the divalent metal ion cofactor.
CC   -!- Formerly EC 4.1.99.10.
DR   A7IZZ1, TPS1_CANSA ;  O22340, TPSDA_ABIGR;
//
ID   4.2.3.17
DE   Taxadiene synthase.
AN   Taxa-4(5),11(12)-diene synthase.
AN   Taxadiene cyclase.
CA   Geranylgeranyl diphosphate = taxa-4,11-diene + diphosphate.
CC   -!- This is the committed step in the biosynthesis of the diterpenoid
CC       antineoplastic drug Taxol (paclitaxel).
CC   -!- The cyclization involves a 1,5-hydride shift.
DR   Q93YA3, TASY_TAXBA ;  Q41594, TASY_TAXBR ;  Q9FT37, TASY_TAXWC ;
//
ID   4.2.3.18
DE   Abietadiene synthase.
AN   Abietadiene cyclase.
CA   (+)-copalyl diphosphate = (-)-abietadiene + diphosphate.
CF   Magnesium.
CC   -!- Part of a bifunctional enzyme involved in the biosynthesis of
CC       abietadiene.
CC   -!- See also EC 5.5.1.12.
DR   Q38710, TPSDV_ABIGR;
//
ID   4.2.3.19
DE   Ent-kaurene synthase.
AN   Ent-kaurene synthase B.
AN   Ent-kaurene synthetase B.
CA   Ent-copalyl diphosphate = ent-kaurene + diphosphate.
CC   -!- Part of a bifunctional enzyme involved in the biosynthesis of ent-
CC       kaurene.
CC   -!- See also EC 5.5.1.13.
DR   Q9UVY5, CPSKS_GIBFU;  O13284, CPSKS_PHASA;  Q0JA82, KS1_ORYSJ  ;
DR   Q9SAK2, KSB_ARATH  ;  Q39548, KSB_CUCMA  ;
//
ID   4.2.3.20
DE   (R)-limonene synthase.
AN   (+)-limonene synthase.
CA   Geranyl diphosphate = (+)-(4R)-limonene + diphosphate.
CF   Manganese.
CC   -!- Forms the first step of carvone biosynthesis in caraway.
DR   Q8L5K3, RLC1_CITLI ;
//
ID   4.2.3.21
DE   Vetispiradiene synthase.
AN   HVS.
AN   Pemnaspirodiene synthase.
AN   Vetispiradiene cyclase.
AN   Vetispiradiene-forming farnesyl pyrophosphate cyclase.
CA   Trans,trans-farnesyl diphosphate = vetispiradiene + diphosphate.
CC   -!- The initial internal cyclization produces the monocyclic intermediate
CC       germacrene A.
DR   Q39978, VTSS1_HYOMU;  Q9XJ32, VTSS1_SOLTU;  Q39979, VTSS2_HYOMU;
DR   Q39980, VTSS3_HYOMU;
//
ID   4.2.3.22
DE   Germacradienol synthase.
AN   Germacradienol/germacrene-D synthase.
CA   (1) (2E,6E)-farnesyl diphosphate + H(2)O = (1E,4S,5E,7R)-germacra-
CA   1(10),5-dien-11-ol + diphosphate.
CA   (2) (2E,6E)-farnesyl diphosphate = (-)-(7S)-germacrene D + diphosphate.
CF   Magnesium.
CC   -!- H-1si of farnesyl diphosphate is lost in the formation of
CC       (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol.
CC   -!- Formation of (-)-germacrene D involves a stereospecific 1,3-hydride
CC       shift of H-1si of farnesyl diphosphate.
CC   -!- Both products are formed from a common intermediate.
CC   -!- The enzyme mediates a key step in the biosynthesis of geosmin (see
CC       EC 4.1.99.16), a widely occurring metabolite of many streptomycetes,
CC       bacteria and fungi.
DR   Q9X839, CYC2_STRCO ;  Q6Q3H3, TPSGD_VITVI;
//
ID   4.2.3.23
DE   Germacrene-A synthase.
AN   (+)-(10R)-germacrene A synthase.
AN   (+)-germacrene A synthase.
AN   GAS.
AN   Germacrene A synthase.
CA   2-trans,6-trans-farnesyl diphosphate = (+)-(R)-germacrene A +
CA   diphosphate.
CF   Magnesium.
CC   -!- While germacrene A is an enzyme-bound intermediate in the
CC       biosynthesis of a number of phytoalexins, e.g. EC 4.2.3.9 from some
CC       species and EC 4.2.3.21, it is the sole sesquiterpenoid product
CC       formed in chicory.
DR   Q8LSC3, GASL_CICIN ;  Q8LSC2, GASS_CICIN ;
//
ID   4.2.3.24
DE   Amorpha-4,11-diene synthase.
AN   Amorphadiene synthase.
CA   2-trans,6-trans-farnesyl diphosphate = amorpha-4,11-diene + diphosphate.
CF   Magnesium; Manganese.
CC   -!- A key enzyme in the biosynthesis of the antimalarial endoperoxide
CC       artemisinin.
CC   -!- Catalyzes the formation of both olefinic and oxygenated
CC       sesquiterpenes, with amorpha-4,11-diene being the major product.
CC   -!- When geranyl diphosphate is used as a substrate, no monoterpenes are
CC       produced.
DR   Q9AR04, AMS1_ARTAN ;
//
ID   4.2.3.25
DE   S-linalool synthase.
AN   3S-linalool synthase.
AN   LIS.
CA   Geranyl diphosphate + H(2)O = (3S)-linalool + diphosphate.
CF   Manganese or magnesium.
CC   -!- Neither (S)- nor (R)-linalyl diphosphate can act as substrate for the
CC       enzyme from Clarkia breweri.
CC   -!- Unlike many other monoterpene synthases, only a single product, (3S)-
CC       linalool, is formed.
DR   Q84UV0, LINS_ARATH ;  Q96376, LIS_CLABR  ;
//
ID   4.2.3.26
DE   R-linalool synthase.
AN   (-)-3R-linalool synthase.
AN   (3R)-linalool synthase.
CA   Geranyl diphosphate + H(2)O = (3R)-linalool + diphosphate.
CF   Manganese or magnesium.
CC   -!- Geranyl diphosphate cannot be replaced by isopentenyl diphosphate,
CC       dimethylallyl diphosphate, farnesyl diphosphate or geranylgeranyl
CC       diphosphate as substrate.
CC   -!- Unlike many other monoterpene synthases, only a single product, (3R)-
CC       linalool, is formed.
DR   Q9SPN0, LLOS1_ARTAN;  Q9SPN1, LLOS5_ARTAN;  Q8H2B4, LLOS_MENAQ ;
DR   Q5SBP3, LLOS_OCIBA ;
//
ID   4.2.3.27
DE   Isoprene synthase.
AN   ISPC.
AN   ISPS.
CA   Dimethylallyl diphosphate = isoprene + diphosphate.
CF   Manganese or magnesium.
CC   -!- Located in the chloroplast of isoprene-emitting plants, such as
CC       poplar and aspen, and may be activitated by light-dependent changes
CC       in chloroplast pH and Mg(2+) concentration.
DR   Q50L36, ISPS_POPAL ;  Q9AR86, ISPS_POPCN ;  Q7XAS7, ISPS_POPTM ;
DR   Q6EJ97, ISPS_PUEML ;
//
ID   4.2.3.28
DE   Ent-cassa-12,15-diene synthase.
CA   Ent-copalyl diphosphate = ent-cassa-12,15-diene + diphosphate.
CC   -!- This class I diterpene cyclase produces ent-cassa-12,15-diene,
CC       a precursor of the rice phytoalexins (-)-phytocassanes A-E.
CC       Phytoalexins are diterpenoid secondary metabolites that are involved
CC       in the defense mechanism of the plant, and are produced in response
CC       to pathogen attack through the perception of elicitor signal
CC       molecules such as chitin oligosaccharide, or after exposure to UV
CC       irradiation.
DR   Q00G37, KSL7_ORYSI ;  Q0E088, KSL7_ORYSJ ;
//
ID   4.2.3.29
DE   Ent-sandaracopimaradiene synthase.
AN   Ent-sandaracopimara-8(14),15-diene synthase.
CA   Ent-copalyl diphosphate = ent-sandaracopimara-8(14),15-diene +
CA   diphosphate.
CC   -!- Ent-sandaracopimaradiene is a precursor of the rice oryzalexins A-F.
CC   -!- Phytoalexins are diterpenoid secondary metabolites that are involved
CC       in the defense mechanism of the plant, and are produced in response
CC       to pathogen attack through the perception of elicitor signal
CC       molecules such as chitin oligosaccharide, or after exposure to UV
CC       irradiation.
CC   -!- As a minor product, this enzyme also forms ent-pimara-8(14),15-diene,
CC       which is the sole product of EC 4.2.3.30.
CC   -!- Ent-pimara-8(14),15-diene is not a precursor in the biosynthesis of
CC       either gibberellins or phytoalexins.
DR   Q2QQJ5, KSL10_ORYSJ;
//
ID   4.2.3.30
DE   Ent-pimara-8(14),15-diene synthase.
CA   Ent-copalyl diphosphate = ent-pimara-8(14),15-diene + diphosphate.
CC   -!- Unlike EC 4.2.3.29 which can produce both ent-sandaracopimaradiene
CC       and ent-pimara-8(14),15-diene, this diterpene cyclase produces only
CC       ent-pimara-8(14),15-diene.
CC   -!- Ent-pimara-8(14),15-diene is not a precursor in the biosynthesis of
CC       either gibberellins or phytoalexins.
DR   Q6Z5J6, KSL5_ORYSJ ;
//
ID   4.2.3.31
DE   Ent-pimara-9(11),15-diene synthase.
AN   PMD synthase.
CA   Ent-copalyl diphosphate = ent-pimara-9(11),15-diene + diphosphate.
CF   Divalent cation.
CC   -!- Involved in the biosynthesis of the diterpenoid viguiepinol.
//
ID   4.2.3.32
DE   Levopimaradiene synthase.
CA   Copalyl diphosphate = abieta-8(14),12-diene + diphosphate.
CC   -!- Levopimaradiene is widely distributed in higher plants.
CC   -!- In Ginkgo, it catalyzes the initial cyclization step in the
CC       biosynthesis of ginkgolides, a structurally unique family of
CC       diterpenoids that are highly specific platelet-activating-factor
CC       receptor antagonists.
CC   -!- In some species the enzyme also forms abietadiene, palustradiene,
CC       and neoabietadiene.
DR   Q947C4, TPSD1_GINBI;  Q675L4, TPSD1_PICAB;  Q50EK2, TPSD1_PINTA;
//
ID   4.2.3.33
DE   Stemar-13-ene synthase.
AN   Stemarene synthase.
AN   Syn-stemar-13-ene synthase.
CA   9-alpha-copalyl diphosphate = stemar-13-ene + diphosphate.
CC   -!- This diterpene cyclase produces stemar-13-ene, a putative precursor
CC       of the rice phytoalexin oryzalexin S.
CC   -!- Phytoalexins are diterpenoid secondary metabolites that are involved
CC       in the defense mechanism of the plant, and are produced in response
CC       to pathogen attack through the perception of elicitor signal
CC       molecules such as chitin oligosaccharide, or after exposure to UV
CC       irradiation.
DR   Q6BDZ9, KSL8_ORYSJ ;
//
ID   4.2.3.34
DE   Stemod-13(17)-ene synthase.
AN   Stemodene synthase.
CA   9-alpha-copalyl diphosphate = stemod-13(17)-ene + diphosphate.
CC   -!- Catalyzes the committed step in the biosynthesis of the stemodane
CC       family of diterpenoid secondary metabolites, some of which possess
CC       mild antiviral activity.
CC   -!- Also produces stemod-12-ene and stemar-13-ene as minor products.
DR   Q1AHB2, KSL11_ORYSI;
//
ID   4.2.3.35
DE   Syn-pimara-7,15-diene synthase.
AN   9-beta-pimara-7,15-diene synthase.
CA   9-alpha-copalyl diphosphate = 9-beta-pimara-7,15-diene + diphosphate.
CC   -!- A class I terpene synthase.
CC   -!- 9-beta-pimara-7,15-diene is a precursor of momilactones A and B, rice
CC       diterpenoid phytoalexins that are produced in response to attack (by
CC       a pathogen, elicitor or UV irradiation) and are involved in the
CC       defense mechanism of the plant.
CC   -!- Momilactone B can also act as an allochemical, being constitutively
CC       produced in the root of the plant and secreted to the rhizosphere
CC       where it suppresses the growth of neighboring plants and soil
CC       microorganisms.
DR   Q66QH3, KSL4_ORYSI ;  Q0JEZ8, KSL4_ORYSJ ;
//
ID   4.2.3.36
DE   Terpentetriene synthase.
CA   Terpentedienyl diphosphate = terpentetriene + diphosphate.
CF   Magnesium.
CC   -!- Following on from EC 5.5.1.15, this enzyme completes the
CC       transformation of geranylgeranyl diphosphate (GGDP) into
CC       terpentetriene, which is a precursor of the diterpenoid antibiotic
CC       terpentecin.
CC   -!- Farnesyl diphosphate can also act as a substrate.
//
ID   4.2.3.37
DE   Epi-isozizaene synthase.
CA   (2E,6E)-farnesyl diphosphate = (+)-epi-isozizaene + diphosphate.
CF   Magnesium.
CC   -!- The displacement of the diphosphate group of farnesyl diphosphate
CC       occurs with retention of configuration.
CC   -!- In the soil-dwelling bacterium Streptomyces coelicolor A3(2),
CC       the product of this reaction is used by EC 1.14.13.106 to produce the
CC       sesquiterpene antibiotic albaflavenone.
DR   Q9K499, CYC1_STRCO ;
//
ID   4.2.3.38
DE   Alpha-bisabolene synthase.
CA   (2E,6E)-farnesyl diphosphate = (E)-alpha-bisabolene + diphosphate.
CF   Magnesium.
CC   -!- While unlikely to encounter geranyl diphosphate (GDP) in vivo as it
CC       is localized to plastids, the enzyme can use GDP as a substrate in
CC       vitro to produce (+)-(4R)-limonene (cf. EC 4.2.3.20).
CC   -!- Induced as part of a defense mechanism in the grand fir Abies grandis
CC       as a response to stem wounding.
CC   -!- Formerly EC 4.2.3.n1.
DR   O81086, TPSD1_ABIGR;  P85964, TPSD1_PSEMZ;
//
ID   4.2.3.39
DE   Epi-cedrol synthase.
AN   8-epicedrol synthase.
AN   Epicedrol synthase.
CA   (2E,6E)-farnesyl diphosphate + H(2)O = 8-epi-cedrol + diphosphate.
CF   Magnesium.
CC   -!- Similar to many other plant terpenoid synthases, this enzyme produces
CC       many products from a single substrate.
CC   -!- The predominant product is the cyclic sesquiterpenoid alcohol, 8-epi-
CC       cedrol, with minor products including cedrol and the olefins alpha-
CC       cedrene, beta-cedrene, (E)-beta-farnesene and (E)-alpha-bisabolene.
DR   Q9LLR9, ECS1_ARTAN ;
//
ID   4.2.3.40
DE   (Z)-gamma-bisabolene synthase.
CA   (2E,6E)-farnesyl diphosphate = (Z)-gamma-bisabolene + diphosphate.
CC   -!- This sesquiterpenoid enzyme is constitutively expressed in the root,
CC       hydathodes and stigma of the plant Arabidopsis thaliana.
CC   -!- If the leaves of the plant are wounded, e.g. by cutting, the enzyme
CC       is also induced close to the wound site.
CC   -!- The sesquiterpenoids (E)-nerolidol and alpha-bisabolol are also
CC       produced by this enzyme as minor products.
DR   Q9T0J9, GBIS1_ARATH;  Q9T0K1, GBIS2_ARATH;
//
ID   4.2.3.41
DE   Elisabethatriene synthase.
AN   Elisabethatriene cyclase.
CA   Geranylgeranyl diphosphate = elisabethatriene + diphosphate.
CF   Magnesium.
CC   -!- Also able to use farnesyl diphosphate and geranyl diphosphate.
//
ID   4.2.3.42
DE   Aphidicolan-16-beta-ol synthase.
AN   ACS.
CA   9-alpha-copalyl diphosphate + H(2) = aphidicolan-16-beta-ol +
CA   diphosphate.
CC   -!- A bifunctional enzyme which also has EC 5.5.1.14 activity.
CC   -!- Aphidicolan-16-beta-ol is a precursor of aphidicolin, a specific
CC       inhibitor of EC 2.7.7.7.
//
ID   4.2.3.43
DE   Fusicocca-2,10(14)-diene synthase.
AN   Fusicoccadiene synthase.
CA   Geranylgeranyl diphosphate = fusicocca-2,10(14)-diene + diphosphate.
CC   -!- A multifunctional enzyme with EC 2.5.1.29 activity.
PR   PROSITE; PDOC00407;
//
ID   4.2.3.44
DE   Isopimara-7,15-diene synthase.
CA   Copalyl diphosphate = isopimara-7,15-diene + diphosphate.
CC   -!- The enzyme only gave isopimara-7,15-diene.
CC   -!- Formerly EC 4.2.3.n9.
DR   Q675L5, TPSD2_PICAB;
//
ID   4.2.3.45
DE   Phyllocladan-16-alpha-ol synthase.
AN   PaDC1.
CA   (+)-copalyl diphosphate + H(2)O = phyllocladan-16-alpha-ol + diphosphate.
//
ID   4.2.3.46
DE   Alpha-farnesene synthase.
AN   (E,E)-alpha-farnesene synthase.
AN   AFS1.
CA   (2E,6E)-farnesyl diphosphate = (3E,6E)-alpha-farnesene + diphosphate.
DR   Q84LB2, AFS1_MALDO ;  A4FVP2, AFS_ARATH  ;  P0CJ43, OCISB_ARATH;
//
ID   4.2.3.47
DE   Beta-farnesene synthase.
AN   Farnesene synthase.
AN   TPS10.
CA   (2E,6E)-farnesyl diphosphate = (E)-beta-farnesene + diphosphate.
DR   Q84ZW8, ACSS_MAIZE ;  Q9FXY7, FARS_ARTAN ;  Q94JS8, FARS_CITJU ;
DR   Q2NM15, FARS_MAIZE ;  C7E5V9, FARS_ZEADI ;  C7E5V8, FARS_ZEAMH ;
DR   C7E5V7, FARS_ZEAMM ;  C7E5W0, FARS_ZEAPE ;  O48935, TPSBF_MENPI;
//
ID   4.2.3.48
DE   (3S,6E)-nerolidol synthase.
AN   (3S)-(E)-nerolidol synthase.
AN   (E)-nerolidol synthase.
AN   Nerolidol synthase.
CA   (2E,6E)-farnesyl diphosphate + H(2)O = (3S,6E)-nerolidol + diphosphate.
CC   -!- The enzyme catalyzes a step in the formation of 4,8-dimethyl-
CC       1,3(E),7-nonatriene, a key signal molecule in induced plant defense
CC       mediated by the attraction of enemies of herbivores (2).
CC   -!- Nerolidol is a naturally occurring sesquiterpene found in the
CC       essential oils of many types of plants.
DR   P0CV94, NES1_FRAAN ;  P0CV96, NES1_FRAVE ;  P0CV95, NES2_FRAAN ;
//
ID   4.2.3.49
DE   (3R,6E)-nerolidol synthase.
CA   (2E,6E)-farnesyl diphosphate + H(2)O = (3R,6E)-nerolidol + diphosphate.
CC   -!- The enzyme catalyzes a step in the formation of (3E)-4,8-dimethyl-
CC       1,3,7-nonatriene, a key signal molecule in induced plant defense
CC       mediated by the attraction of enemies of herbivores (1).
CC   -!- Nerolidol is a naturally occurring sesquiterpene found in the
CC       essential oils of many types of plants.
DR   Q84ZW8, ACSS_MAIZE ;
//
ID   4.2.3.50
DE   (+)-alpha-santalene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing).
CA   (2Z,6Z)-farnesyl diphosphate = (+)-alpha-santalene.
CC   -!- The enzyme synthesizes a mixture of sesquiterpenoids from (2Z,6Z)-
CC       farnesyl diphosphate.
CC   -!- Following dephosphorylation of (2Z,6Z)-farnesyl diphosphate,
CC       the (2Z,6Z)-farnesyl carbocation is converted to either the (6R)- or
CC       the (6S)-bisabolyl cations depending on the stereochemistry of the
CC       6,1 closure.
CC   -!- The (6R)-bisabolyl cation will then lead to the formation of (+)-
CC       alpha-santalene (EC 4.2.3.50), while the (6S)-bisabolyl cation will
CC       give rise to (+)-endo-beta-bergamotene (see EC 4.2.3.53) as well as
CC       (-)-endo-alpha-bergamotene (see EC 4.2.3.54).
CC   -!- Small amounts of (-)-epi-beta-santalene are also formed from the
CC       (6R)-bisabolyl cation and small amounts of (-)-exo-alpha-bergamotene
CC       are formed from the (6S)-bisabolyl cation.
DR   B8XA41, SBS_SOLHA  ;
//
ID   4.2.3.51
DE   Beta-phellandrene synthase (neryl-diphosphate-cyclizing).
AN   Phellandrene synthase 1.
CA   Neryl diphosphate = beta-phellandrene + diphosphate.
CC   -!- The enzyme from Solanum lycopersicum has very poor affinity with
CC       geranyl diphosphate as substrate.
CC   -!- Catalyzes the formation of the acyclic myrcene and ocimene as major
CC       products in addition to beta-phellandrene.
DR   C1K5M3, PHS1_SOLLC ;
//
ID   4.2.3.52
DE   (4S)-beta-phellandrene synthase (geranyl-diphosphate-cyclizing).
AN   (-)-(4S)-beta-phellandrene synthase.
AN   (-)-beta-phellandrene synthase.
CA   Geranyl diphosphate = (4S)-beta-phellandrene + diphosphate.
CF   Manganese.
CC   -!- Mg(2+) is not effective.
CC   -!- Some (-)-alpha-phellandrene is also formed.
CC   -!- The reaction involves a 1,3-hydride shift.
CC   -!- Formerly EC 4.2.3.n5.
DR   Q9M7D1, TPSD8_ABIGR;
//
ID   4.2.3.53
DE   (+)-endo-beta-bergamotene synthase ((2Z,6Z)-farnesyl diphosphate
DE   cyclizing).
CA   (2Z,6Z)-farnesyl diphosphate = (+)-endo-beta-bergamotene.
CC   -!- The enzyme synthesizes a mixture of sesquiterpenoids from (2Z,6Z)-
CC       farnesyl diphosphate.
CC   -!- Following dephosphorylation of (2Z,6Z)-farnesyl diphosphate,
CC       the (2Z,6Z)-farnesyl carbocation is converted to either the (6R)- or
CC       the (6S)-bisabolyl cations depending on the stereochemistry of the
CC       6,1 closure.
CC   -!- The (6R)-bisabolyl cation will then lead to the formation of (+)-
CC       alpha-santalene (see EC 4.2.3.50), while the (6S)-bisabolyl cation
CC       will give rise to (-)-endo-alpha-bergamotene (see EC 4.2.3.54),
CC       as well as (+)-endo-beta-bergamotene.
CC   -!- Small amounts of (-)-epi-beta-santalene are also formed from the
CC       (6R)-bisabolyl cation and small amounts of (-)-exo-alpha-bergamotene
CC       are formed from the (6S)-bisabolyl cation.
DR   B8XA41, SBS_SOLHA  ;
//
ID   4.2.3.54
DE   (-)-endo-alpha-bergamotene synthase ((2Z,6Z)-farnesyl diphosphate
DE   cyclizing).
CA   (2Z,6Z)-farnesyl diphosphate = (-)-endo-alpha-bergamotene.
CC   -!- The enzyme synthesizes a mixture of sesquiterpenoids from (2Z,6Z)-
CC       farnesyl diphosphate.
CC   -!- Following dephosphorylation of (2Z,6Z)-farnesyl diphosphate,
CC       the (2Z,6Z)-farnesyl carbocation is converted to either the (6R)- or
CC       the (6S)-bisabolyl cations depending on the stereochemistry of the
CC       6,1 closure.
CC   -!- The (6R)-bisabolyl cation will then lead to the formation of (+)-
CC       alpha-santalene (see EC 4.2.3.50), while the (6S)-bisabolyl cation
CC       will give rise to (+)-endo-beta-bergamotene (EC 4.2.3.53) as well as
CC       (-)-endo-alpha-bergamotene.
CC   -!- Small amounts of (-)-epi-beta-santalene are also formed from the
CC       (6R)-bisabolyl cation and small amounts of (-)-exo-alpha-bergamotene
CC       are formed from the (6S)-bisabolyl cation (1).
DR   B8XA41, SBS_SOLHA  ;
//
ID   4.2.3.55
DE   (S)-beta-bisabolene synthase.
CA   (2E,6E)-farnesyl diphosphate = (S)-beta-bisabolene + diphosphate.
CF   Manganese or magnesium.
CC   -!- The synthesis of (S)-beta-macrocarpene from (2E,6E)-farnesyl
CC       diphosphate proceeds in two steps.
CC   -!- The first step is the cyclization to (S)-beta-bisabolene.
CC   -!- The second step is the isomerization to (S)-beta-macrocarpene (cf.
CC       EC 5.5.1.17, (S)-beta-macrocarpene synthase).
DR   D2YZP9, BISS_ZINOF ;
//
ID   4.2.3.56
DE   Gamma-humulene synthase.
CA   Farnesyl-diphosphate = gamma-humulene + diphosphate.
CF   Manganese or magnesium.
CC   -!- Has a broad product range.
CC   -!- While gamma-humulene is the major product, sibirene, longifolene,
CC       beta-himachalene, gamma-himachalene and alpha-himachalene are
CC       produced in appreciable amounts and further 47 other minor products
CC       can also be detected.
CC   -!- The enzyme can use geranyl diphosphate as a substrate, producing
CC       mainly limonene and terpinolene as the major products.
CC   -!- Formerly EC 4.2.3.n3.
DR   O64405, TPSD5_ABIGR;
//
ID   4.2.3.57
DE   Beta-caryophyllene synthase.
CA   (2E,6E)-farnesyl diphosphate = beta-caryophyllene + diphosphate.
DR   Q8SA63, CARS_ARTAN ;
//
ID   4.2.3.58
DE   Longifolene synthase.
CA   (2E,6E)-farnesyl diphosphate = longifolene + diphosphate.
CC   -!- As well as 61% longifolene the enzyme gives 15% of alpha-longipinene,
CC       6% longicyclene and traces of other sesquiterpenoids.
DR   Q675L0, TPSLS_PICAB;
//
ID   4.2.3.59
DE   (E)-gamma-bisabolene synthase.
CA   (2E,6E)-farnesyl diphosphate = (E)-gamma-bisabolene + diphosphate.
DR   Q4QSN4, TPSBS_PSEMZ;
//
ID   4.2.3.60
DE   Germacrene C synthase.
CA   (2E,6E)-farnesyl diphosphate = germacrene C + diphosphate.
DR   O64961, TPSGC_SOLLC;
//
ID   4.2.3.61
DE   5-epiaristolochene synthase.
AN   5-epi-aristolochene synthase.
AN   Farnesyl pyrophosphate cyclase.
CA   (2E,6E)-farnesyl diphosphate = (+)-5-epiaristolochene + diphosphate.
CC   -!- Initial cyclization gives (+)-germacrene A in an enzyme bound form
CC       which is not released to the medium.
DR   Q84LF1, 5EAS1_NICAT;  Q84LF0, 5EAS2_NICAT;  Q84LF2, 5EAS3_NICAT;
DR   Q84LG0, 5EAS4_NICAT;  O65323, 5EAS_CAPAN ;  Q40577, 5EAS_TOBAC ;
//
ID   4.2.3.62
DE   (-)-gamma-cadinene synthase.
AN   (-)-gamma-cadinene cyclase.
CA   (2Z,6E)-farnesyl diphosphate = (-)-gamma-cadinene + diphosphate.
//
ID   4.2.3.63
DE   (+)-cubenene synthase.
CA   (2E,6E)-farnesyl diphosphate = (+)-cubenene + diphosphate.
CF   Magnesium.
//
ID   4.2.3.64
DE   (+)-epicubenol synthase.
AN   Farnesyl pyrophosphate cyclase.
CA   (2E,6E)-farnesyl diphosphate + H(2)O = (+)-epicubenol + diphosphate.
CF   Magnesium.
CC   -!- In the bacteria Streptomyces and the liverwort Heteroscyphus the (+)-
CC       isomer is formed in contrast to higher plants where the (-)-isomer is
CC       formed.
//
ID   4.2.3.65
DE   Zingiberene synthase.
AN   Alpha-zingiberene synthase.
AN   ZIS.
CA   (2E,6E)-farnesyl diphosphate = zingiberene + diphosphate.
CC   -!- Formerly EC 4.2.3.n12.
DR   Q5SBP4, AZIS_OCIBA ;
//
ID   4.2.3.66
DE   Beta-selinene cyclase.
CA   (2E,6E)-farnesyl diphosphate = beta-selinene + diphosphate.
//
ID   4.2.3.67
DE   Cis-muuroladiene synthase.
CA   (1) (2E,6E)-farnesyl diphosphate = cis-muurola-3,5-diene + diphosphate.
CA   (2) (2E,6E)-farnesyl diphosphate = cis-muurola-4(14),5-diene +
CA   diphosphate.
CC   -!- The recombinant enzyme from black peppermint (Mentha x piperita) gave
CC       a mixture of cis-muurola-3,5-diene (45%) and cis-muurola-4(14),5-
CC       diene (43%).
DR   Q5W283, TPSCM_MENPI;
//
ID   4.2.3.68
DE   Beta-eudesmol synthase.
CA   (1) (2E,6E)-farnesyl diphosphate + H(2)O = beta-eudesmol + diphosphate.
CA   (2) (2E,6E)-farnesyl diphosphate + H(2)O = 10-epi-gamma-eudesmol +
CA   diphosphate.
CA   (3) (2E,6E)-farnesyl diphosphate + H(2)O = alpha-eudesmol + diphosphate.
CC   -!- The recombinant enzyme from ginger (Zingiber zerumbet) gives 62.6%
CC       beta-eudesmol, 16.8% 10-epi-gamma-eudesmol, 10% alpha-eudesmol,
CC       and 5.6% aristolene.
DR   B1B1U4, TPSBE_ZINZE;
//
ID   4.2.3.69
DE   (+)-alpha-barbatene synthase.
CA   (1) (2E,6E)-farnesyl diphosphate = (+)-alpha-barbatene + diphosphate.
CA   (2) (2E,6E)-farnesyl diphosphate = (+)-thujopsene + diphosphate.
CA   (3) (2E,6E)-farnesyl diphosphate = (+)-beta-chamigrene + diphosphate.
CC   -!- The recombinant enzyme from the plant Arabidopsis thaliana produces
CC       27.3% alpha-barbatene, 17.8% thujopsene and 9.9% beta-chamigrene plus
CC       traces of other sesquiterpenoids.
DR   Q4KSH9, BARS_ARATH ;
//
ID   4.2.3.70
DE   Patchoulol synthase.
CA   (2E,6E)-farnesyl diphosphate + H(2)O = patchoulol + diphosphate.
DR   Q49SP3, TPSPS_POGCB;
//
ID   4.2.3.71
DE   (E,E)-germacrene B synthase.
CA   (2E,6E)-farnesyl diphosphate = (E,E)-germacrene B + diphosphate.
DR   Q9FQ27, TPSGB_SOLHA;
//
ID   4.2.3.72
DE   Alpha-gurjunene synthase.
CA   (2E,6E)-farnesyl diphosphate = (-)-alpha-gurjunene + diphosphate.
CC   -!- Initial cyclization probably gives biyclogermacrene in an enzyme
CC       bound form which is not released to the medium.
CC   -!- The enzyme from Solidago canadensis also forms a small amount of (+)-
CC       gamma-gurjunene.
//
ID   4.2.3.73
DE   Valencene synthase.
CA   (1) (2E,6E)-farnesyl diphosphate = (+)-valencene + diphosphate.
CA   (2) (2E,6E)-farnesyl diphosphate = (-)-7-epi-alpha-selinene +
CA   diphosphate.
CC   -!- The recombinant enzyme from Vitis vinifera gave 49.5% (+)-valencene
CC       and 35.5% (-)-7-epi-alpha-selinene.
CC   -!- Initial cyclization gives (+)-germacrene A in an enzyme bound form
CC       which is not released to the medium.
DR   Q6Q3H2, TPSVS_VITVI;
//
ID   4.2.3.74
DE   Presilphiperfolanol synthase.
CA   (2E,6E)-farnesyl diphosphate + H(2)O = presilphiperfolan-8-beta-ol +
CA   diphosphate.
CF   Magnesium.
CC   -!- Presilphiperfolan-8-beta-ol is the precursor of botrydial,
CC       a phytotoxic sesquiterpene metabolite secreted by the fungus
CC       Botryotinia fuckeliana (Botrytis cinerea), the causal agent of gray
CC       mold disease in plants.
DR   Q6WP50, BOT2_BOTFU ;
//
ID   4.2.3.n1
DE   Transferred entry: 4.2.3.38.
//
ID   4.2.3.n2
DE   Delta-selinene synthase.
CA   (1) Farnesyl-diphosphate = delta-selinene + diphosphate.
CA   (2) Farnesyl-diphosphate = (E,E)-germacrene B + diphosphate.
CA   (3) Farnesyl-diphosphate = guaia-6,9-diene + diphosphate.
CA   (4) Farnesyl-diphosphate = germacrene A + diphosphate.
CA   (5) Farnesyl-diphosphate = (+)-delta-cadinene + diphosphate.
CF   Magnesium.
CC   -!- Has a broad product range.
CC   -!- While delta-selinene is the major product, (E,E)-germacrene B, guaia-
CC       6,9-diene, germacrene A and delta-cadinene are produced in
CC       appreciable amounts and further 29 other minor products can also be
CC       detected.
CC   -!- The enzyme can use geranyl diphosphate as a substrate, producing
CC       mainly limonene, (Z)-ocimene and myrcene as the major products.
DR   O64404, TPSD4_ABIGR;
//
ID   4.2.3.n3
DE   Transferred entry: 4.2.3.56.
//
ID   4.2.3.n4
DE   (-)-camphene synthase.
AN   (-)-(1S,4R)-camphene synthase.
CA   (1) Geranyl-diphosphate = (-)-camphene + diphosphate.
CA   (2) Geranyl-diphosphate = (-)-alpha-pinene + diphosphate.
CA   (3) Geranyl-diphosphate = (-)-(S)-limonene + diphosphate.
CC   -!- The three main products are (-)-camphene (54%), (-)-alpha-pinene
CC       (32%) and (-)-(S)-limonene (7%).
CC   -!- The protein is not stereoselective as (-)-alpha-pinene and (+)-alpha-
CC       pinene is produced in a ratio of 95:5.
DR   Q948Z0, TPSD6_ABIGR;
//
ID   4.2.3.n5
DE   Transferred entry: 4.2.3.52.
//
ID   4.2.3.n6
DE   Terpinolene synthase.
CA   (1) Geranyl-diphosphate = terpinolene + diphosphate.
CA   (2) Geranyl-diphosphate = (-)-beta-pinene + diphosphate.
CA   (3) Geranyl-diphosphate = (-)-(S)-limonene + diphosphate.
CA   (4) Geranyl-diphosphate = (-)-alpha-pinene + diphosphate.
CC   -!- The four main products are terpinolene (42%), (-)-alpha-pinene (18%),
CC       (-)-(S)-limonene (11%) and (-)-beta-pinene (10%).
DR   Q9M7D0, TPSD9_ABIGR;  Q5SBP0, TPSD_OCIBA ;
//
ID   4.2.3.n7
DE   (-)-(S)-limonene/(-)-alpha-pinene synthase.
AN   (-)-camphene synthase.
CA   (1) Geranyl-diphosphate = (-)-(S)-limonene + diphosphate.
CA   (2) Geranyl-diphosphate = (-)-alpha-pinene + diphosphate.
CA   (3) Geranyl-diphosphate = (-)-beta-pinene + diphosphate.
CA   (4) Geranyl-diphosphate = beta-phellandrene + diphosphate.
CA   (5) Geranyl-diphosphate = (-)-sabinene + diphosphate.
CC   -!- The five main products are (-)-(S)-limonene (35%), (-)-alpha-pinene
CC       (24%), beta-phellandrene (20%), (-)-beta-pinene (11%) and (-)-
CC       sabinene (10%).
DR   Q9M7C9, TPSDB_ABIGR;
//
ID   4.2.3.n8
DE   Ent-isokaurene synthase.
AN   Ent-isokaur-15-ene synthase.
CA   Ent-copalyl diphosphate = ent-isokaur-15-ene + diphosphate.
DR   A4KAG7, KSL5_ORYSI ;  A4KAG8, KSL6_ORYSJ ;
//
ID   4.2.3.n9
DE   Transferred entry: 4.2.3.44.
//
ID   4.2.3.n12
DE   Transferred entry: 4.2.3.65.
//
ID   4.2.3.n14
DE   2-methylisoborneol synthase.
AN   2-MIB synthase.
CA   (E)-2-methylgeranyl diphosphate + H(2)O = 2-methylisoborneol +
CA   diphosphate.
CF   Magnesium.
CC   -!- The enzyme from Streptomyces coelicolor is involved in the
CC       biosynthesis of the earthy odorant methylisoborneol.
DR   A4FG19, MIBS_SACEN ;  A3KI17, MIBS_STRAM ;  Q9F1Y6, MIBS_STRCO ;
DR   Q9F1V8, MIBS_STRGR ;  D3KYU2, MIBS_STRLS ;
//
ID   4.2.99.1
DE   Transferred entry: 4.2.2.1.
//
ID   4.2.99.2
DE   Transferred entry: 4.2.3.1.
//
ID   4.2.99.3
DE   Transferred entry: 4.2.2.2.
//
ID   4.2.99.4
DE   Transferred entry: 4.2.2.3.
//
ID   4.2.99.5
DE   Deleted entry.
//
ID   4.2.99.6
DE   Transferred entry: 4.2.2.5, 4.2.2.20 and 4.2.2.21.
//
ID   4.2.99.7
DE   Transferred entry: 4.2.3.2.
//
ID   4.2.99.8
DE   Transferred entry: 2.5.1.47.
//
ID   4.2.99.9
DE   Transferred entry: 2.5.1.48.
//
ID   4.2.99.10
DE   Transferred entry: 2.5.1.49.
//
ID   4.2.99.11
DE   Transferred entry: 4.2.3.3.
//
ID   4.2.99.12
DE   Carboxymethyloxysuccinate lyase.
CA   Carboxymethyloxysuccinate = fumarate + glycolate.
//
ID   4.2.99.13
DE   Transferred entry: 2.5.1.50.
//
ID   4.2.99.14
DE   Transferred entry: 2.5.1.51.
//
ID   4.2.99.15
DE   Transferred entry: 2.5.1.52.
//
ID   4.2.99.16
DE   Transferred entry: 2.5.1.53.
//
ID   4.2.99.17
DE   Transferred entry: 2.5.1.51.
//
ID   4.2.99.18
DE   DNA-(apurinic or apyrimidinic site) lyase.
AN   AP endonuclease class I.
AN   AP lyase.
AN   Deoxyribonuclease (apurinic or apyrimidinic).
AN   E.coli endonuclease III.
AN   Endodeoxyribonuclease (apurinic or apyrimidinic).
AN   Micrococcus luteus UV endonuclease.
AN   Phage-T(4) UV endonuclease.
AN   Phage-T4 UV endonuclease.
CA   The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken
CA   by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar
CA   and a product with a terminal 5'-phosphate.
CC   -!- 'Nicking' of the phosphodiester bond is due to a lyase-type reaction,
CC       not hydrolysis.
CC   -!- This group of enzymes was previously listed as endonucleases, under
CC       the number EC 3.1.25.2.
PR   PROSITE; PDOC00598;
PR   PROSITE; PDOC00599;
PR   PROSITE; PDOC00615;
DR   Q9YE60, AGOG_AERPE ;  Q8TXW8, AGOG_METKA ;  Q6M0G7, AGOG_METMP ;
DR   Q74MX2, AGOG_NANEQ ;  Q9UZY0, AGOG_PYRAB ;  Q8ZVK6, AGOG_PYRAE ;
DR   Q8U2D5, AGOG_PYRFU ;  O58954, AGOG_PYRHO ;  Q5JI79, AGOG_PYRKO ;
DR   Q13686, ALKB1_HUMAN;  P0CB42, ALKB1_MOUSE;  P51173, APEA_DICDI ;
DR   P23196, APEX1_BOVIN;  A0MTA1, APEX1_DANRE;  A1YES6, APEX1_GORGO;
DR   P27695, APEX1_HUMAN;  P28352, APEX1_MOUSE;  A1YFZ3, APEX1_PANPA;
DR   A2T6Y4, APEX1_PANTR;  A2T7I6, APEX1_PONPY;  P43138, APEX1_RAT  ;
DR   Q5E9N9, APEX2_BOVIN;  Q9UBZ4, APEX2_HUMAN;  Q68G58, APEX2_MOUSE;
DR   A0JNH9, APLF_BOVIN ;  A8JR14, APLF_DROME ;  Q8IW19, APLF_HUMAN ;
DR   Q9D842, APLF_MOUSE ;  Q10002, APN1_CAEEL ;  P50525, APN1_SCHPO ;
DR   P22936, APN1_YEAST ;  P87175, APN2_SCHPO ;  P38207, APN2_YEAST ;
DR   P45951, ARP_ARATH  ;  P39788, END3_BACSU ;  P57219, END3_BUCAI ;
DR   Q8KA16, END3_BUCAP ;  Q89AW4, END3_BUCBP ;  P0AB84, END3_ECOL6 ;
DR   P0AB83, END3_ECOLI ;  P44319, END3_HAEIN ;  P63541, END3_MYCBO ;
DR   Q9CB92, END3_MYCLE ;  P63540, END3_MYCTU ;  Q92GH4, END3_RICCN ;
DR   Q4UK93, END3_RICFE ;  O05956, END3_RICPR ;  Q68W04, END3_RICTY ;
DR   P73715, END3_SYNY3 ;  Q9WYK0, END3_THEMA ;  O83754, END3_TREPA ;
DR   A8AJA5, END8_CITK8 ;  A7ZJ95, END8_ECO24 ;  B7ULJ5, END8_ECO27 ;
DR   B7MFX3, END8_ECO45 ;  B7LAC0, END8_ECO55 ;  Q8X9C6, END8_ECO57 ;
DR   B7NMR0, END8_ECO7I ;  B7MPL0, END8_ECO81 ;  B7M5M8, END8_ECO8A ;
DR   C4ZWI9, END8_ECOBW ;  B1X6P5, END8_ECODH ;  A7ZXX5, END8_ECOHS ;
DR   A1A8X0, END8_ECOK1 ;  Q0TJX8, END8_ECOL5 ;  Q8FJU5, END8_ECOL6 ;
DR   B1IY15, END8_ECOLC ;  P50465, END8_ECOLI ;  B7N9V3, END8_ECOLU ;
DR   B6I7Y5, END8_ECOSE ;  B1LLF1, END8_ECOSM ;  Q1REK9, END8_ECOUT ;
DR   A4W871, END8_ENT38 ;  A7MQW6, END8_ENTS8 ;  Q6D7H0, END8_ERWCT ;
DR   B5XZD9, END8_KLEP3 ;  A6T6E8, END8_KLEP7 ;  C6DCC8, END8_PECCP ;
DR   B5EZF2, END8_SALA4 ;  A9MJM8, END8_SALAR ;  Q57RM1, END8_SALCH ;
DR   B5FNF0, END8_SALDC ;  B5QWF8, END8_SALEP ;  B5R679, END8_SALG2 ;
DR   B4TBC8, END8_SALHS ;  B4SZD3, END8_SALNS ;  Q5PCL7, END8_SALPA ;
DR   A9MTR2, END8_SALPB ;  C0PWD7, END8_SALPC ;  B5BC82, END8_SALPK ;
DR   B4TQ44, END8_SALSV ;  Q8Z8D2, END8_SALTI ;  E1W9M1, END8_SALTS ;
DR   P0CL05, END8_SALTY ;  B2TU97, END8_SHIB3 ;  Q324J6, END8_SHIBS ;
DR   Q32IL9, END8_SHIDS ;  Q0T6V4, END8_SHIF8 ;  Q83LZ7, END8_SHIFL ;
DR   Q3Z489, END8_SHISS ;  B0C5D4, FPG_ACAM1  ;  Q6FE90, FPG_ACIAD  ;
DR   B0VRV3, FPG_ACIBS  ;  A0LV85, FPG_ACIC1  ;  A5FZ95, FPG_ACICJ  ;
DR   B9ME52, FPG_ACIET  ;  B7J8I7, FPG_ACIF2  ;  B5ENT6, FPG_ACIF5  ;
DR   A1W4G6, FPG_ACISJ  ;  A3N3S8, FPG_ACTP2  ;  B3GZD6, FPG_ACTP7  ;
DR   B0BU16, FPG_ACTPJ  ;  A6VKA1, FPG_ACTSZ  ;  A0KEN2, FPG_AERHH  ;
DR   A4STD1, FPG_AERS4  ;  Q8UIH4, FPG_AGRT5  ;  B9JZF5, FPG_AGRVS  ;
DR   Q0VLB7, FPG_ALCBS  ;  Q0A598, FPG_ALHEH  ;  B4S2C6, FPG_ALTMD  ;
DR   Q3MDP1, FPG_ANAVT  ;  Q5P728, FPG_AROAE  ;  A8IQM5, FPG_AZOC5  ;
DR   Q81L04, FPG_BACAN  ;  Q72ZF1, FPG_BACC1  ;  Q817G5, FPG_BACCR  ;
DR   Q633L1, FPG_BACCZ  ;  P19210, FPG_BACFI  ;  Q9K855, FPG_BACHD  ;
DR   Q6HCU5, FPG_BACHK  ;  Q65G93, FPG_BACLD  ;  Q5WEG7, FPG_BACSK  ;
DR   O34403, FPG_BACSU  ;  A1UU20, FPG_BARBK  ;  Q6G4T2, FPG_BARHE  ;
DR   Q6G0L3, FPG_BARQU  ;  A9IN26, FPG_BART1  ;  Q1LTS6, FPG_BAUCH  ;
DR   Q6ML45, FPG_BDEBA  ;  B2IE81, FPG_BEII9  ;  Q2KYB7, FPG_BORA1  ;
DR   Q7W185, FPG_BORPA  ;  A9I6Y3, FPG_BORPD  ;  Q7VUG7, FPG_BORPE  ;
DR   Q89WC9, FPG_BRAJA  ;  A5E887, FPG_BRASB  ;  A4YJG9, FPG_BRASO  ;
DR   C0Z7Z0, FPG_BREBN  ;  B2S9T2, FPG_BRUA1  ;  Q2YQP8, FPG_BRUA2  ;
DR   Q57A83, FPG_BRUAB  ;  A9MAB2, FPG_BRUC2  ;  C0RG65, FPG_BRUMB  ;
DR   Q8YED2, FPG_BRUME  ;  A5VTD0, FPG_BRUO2  ;  Q8FXR6, FPG_BRUSU  ;
DR   B1YN48, FPG_BURA4  ;  Q1BTH0, FPG_BURCA  ;  A0KAM1, FPG_BURCH  ;
DR   B4EAR7, FPG_BURCJ  ;  A9AEZ2, FPG_BURM1  ;  A2S6C0, FPG_BURM9  ;
DR   Q62FC7, FPG_BURMA  ;  A1UZN2, FPG_BURMS  ;  A3NRA1, FPG_BURP0  ;
DR   Q3JW82, FPG_BURP1  ;  A3N5K5, FPG_BURP6  ;  B2JCP3, FPG_BURP8  ;
DR   B2SXG9, FPG_BURPP  ;  Q63XL4, FPG_BURPS  ;  Q39CU4, FPG_BURS3  ;
DR   Q2T1B3, FPG_BURTA  ;  A4JHZ1, FPG_BURVG  ;  Q145W8, FPG_BURXL  ;
DR   Q3ABL4, FPG_CARHZ  ;  B8GVY4, FPG_CAUCN  ;  Q9A259, FPG_CAUCR  ;
DR   B0T7D1, FPG_CAUSK  ;  B3PG51, FPG_CELJU  ;  A9WDC2, FPG_CHLAA  ;
DR   B8G9X1, FPG_CHLAD  ;  Q7NQS5, FPG_CHRVO  ;  A8ARM2, FPG_CITK8  ;
DR   Q48AD4, FPG_COLP3  ;  C3PH91, FPG_CORA7  ;  Q6NGH4, FPG_CORDI  ;
DR   Q8FP17, FPG_COREF  ;  A4QFD9, FPG_CORGB  ;  Q8NNV7, FPG_CORGL  ;
DR   Q4JUY8, FPG_CORJK  ;  B1VG60, FPG_CORU7  ;  Q0KEP4, FPG_CUPNH  ;
DR   Q476F5, FPG_CUPPJ  ;  B2AGU2, FPG_CUPTR  ;  B1WTF7, FPG_CYAA5  ;
DR   B7K1T1, FPG_CYAP8  ;  Q479M6, FPG_DECAR  ;  Q9RX22, FPG_DEIRA  ;
DR   C6BUX8, FPG_DESAD  ;  B8FU83, FPG_DESHD  ;  Q24XW2, FPG_DESHY  ;
DR   Q6APT2, FPG_DESPS  ;  A4J4X3, FPG_DESRM  ;  Q726D5, FPG_DESVH  ;
DR   A5EXK6, FPG_DICNV  ;  A8LNK8, FPG_DINSH  ;  A7ZTI6, FPG_ECO24  ;
DR   B7ULJ0, FPG_ECO27  ;  B7MFJ6, FPG_ECO45  ;  B7L758, FPG_ECO55  ;
DR   P64148, FPG_ECO57  ;  B5YWD3, FPG_ECO5E  ;  B7NPE1, FPG_ECO7I  ;
DR   B7N2X1, FPG_ECO81  ;  B7M4B9, FPG_ECO8A  ;  C4ZXM7, FPG_ECOBW  ;
DR   B1X969, FPG_ECODH  ;  A8A697, FPG_ECOHS  ;  A1AHG8, FPG_ECOK1  ;
DR   Q0TBH4, FPG_ECOL5  ;  Q8FC87, FPG_ECOL6  ;  B1IZF8, FPG_ECOLC  ;
DR   P05523, FPG_ECOLI  ;  B7NET9, FPG_ECOLU  ;  B6I3L2, FPG_ECOSE  ;
DR   B1LK72, FPG_ECOSM  ;  Q1R4V8, FPG_ECOUT  ;  C5B9D8, FPG_EDWI9  ;
DR   A4W514, FPG_ENT38  ;  Q837G3, FPG_ENTFA  ;  A7MQ97, FPG_ENTS8  ;
DR   Q6DAV4, FPG_ERWCT  ;  B2VF70, FPG_ERWT9  ;  Q2N7Y8, FPG_ERYLH  ;
DR   B7LVJ6, FPG_ESCF3  ;  B1YKA0, FPG_EXIS2  ;  C4L470, FPG_EXISA  ;
DR   A8L594, FPG_FRASN  ;  Q5NGY3, FPG_FRATT  ;  Q5KWC3, FPG_GEOKA  ;
DR   Q39WD1, FPG_GEOMG  ;  B9M5V2, FPG_GEOSF  ;  Q74EG5, FPG_GEOSL  ;
DR   A5G7Q9, FPG_GEOUR  ;  Q7NFW7, FPG_GLOVI  ;  A9HI30, FPG_GLUDA  ;
DR   Q5FN17, FPG_GLUOX  ;  Q7VN67, FPG_HAEDU  ;  Q4QLW2, FPG_HAEI8  ;
DR   A5UDC3, FPG_HAEIE  ;  A5UI87, FPG_HAEIG  ;  P44948, FPG_HAEIN  ;
DR   B8F586, FPG_HAEPS  ;  Q0I0X6, FPG_HAES1  ;  B0UUX0, FPG_HAES2  ;
DR   Q2SPF3, FPG_HAHCH  ;  A1WZG2, FPG_HALHL  ;  B0TER7, FPG_HELMI  ;
DR   A9B0X2, FPG_HERA2  ;  A4G916, FPG_HERAR  ;  Q5QZC1, FPG_IDILO  ;
DR   A6T2R7, FPG_JANMA  ;  Q28JI5, FPG_JANSC  ;  A6W7S6, FPG_KINRD  ;
DR   B5XTG8, FPG_KLEP3  ;  A6TFM6, FPG_KLEP7  ;  Q5FIV8, FPG_LACAC  ;
DR   Q1G9A3, FPG_LACDA  ;  Q049F3, FPG_LACDB  ;  Q041U1, FPG_LACGA  ;
DR   A8YWE6, FPG_LACH4  ;  Q74IB5, FPG_LACJO  ;  Q9CIK4, FPG_LACLA  ;
DR   P42371, FPG_LACLC  ;  Q88WV4, FPG_LACPL  ;  Q1WUN7, FPG_LACS1  ;
DR   Q38VS5, FPG_LACSS  ;  C1DBB4, FPG_LARHH  ;  Q5X7I9, FPG_LEGPA  ;
DR   Q5ZY18, FPG_LEGPH  ;  Q5WYY6, FPG_LEGPL  ;  Q6AFJ3, FPG_LEIXX  ;
DR   B1Y3P5, FPG_LEPCP  ;  Q92BF1, FPG_LISIN  ;  Q71ZA3, FPG_LISMF  ;
DR   Q8Y6W7, FPG_LISMO  ;  A0L837, FPG_MAGSM  ;  Q65R59, FPG_MANSM  ;
DR   A1U749, FPG_MARAV  ;  A6VSY6, FPG_MARMS  ;  Q11AV8, FPG_MESSB  ;
DR   B7KN75, FPG_METC4  ;  Q602J1, FPG_METCA  ;  A9W8R7, FPG_METEP  ;
DR   Q1H3I3, FPG_METFK  ;  B8IIZ9, FPG_METNO  ;  B1ZGU8, FPG_METPB  ;
DR   B1LWY6, FPG_METRJ  ;  B0UR68, FPG_METS4  ;  B8EKR5, FPG_METSB  ;
DR   Q5UQ00, FPG_MIMIV  ;  Q2RHE9, FPG_MOOTA  ;  A0QJ66, FPG_MYCA1  ;
DR   B1MDL2, FPG_MYCA9  ;  P64151, FPG_MYCBO  ;  A1KMR9, FPG_MYCBP  ;
DR   C1AG40, FPG_MYCBT  ;  P55825, FPG_MYCGE  ;  A4TE57, FPG_MYCGI  ;
DR   B8ZRZ2, FPG_MYCLB  ;  O69470, FPG_MYCLE  ;  B2HJJ6, FPG_MYCMM  ;
DR   Q6KHS0, FPG_MYCMO  ;  Q73VL9, FPG_MYCPA  ;  P75402, FPG_MYCPN  ;
DR   Q98QQ1, FPG_MYCPU  ;  A0QV21, FPG_MYCS2  ;  A3PXU1, FPG_MYCSJ  ;
DR   A1UED7, FPG_MYCSK  ;  Q1BAM5, FPG_MYCSS  ;  A5U6T0, FPG_MYCTA  ;
DR   P64150, FPG_MYCTU  ;  A0PQ49, FPG_MYCUA  ;  A1T737, FPG_MYCVP  ;
DR   Q5F8Z9, FPG_NEIG1  ;  P57014, FPG_NEIMA  ;  P55044, FPG_NEIMB  ;
DR   Q0AD66, FPG_NITEC  ;  Q82S12, FPG_NITEU  ;  Q2YBI1, FPG_NITMU  ;
DR   Q3J7U5, FPG_NITOC  ;  Q3SWN3, FPG_NITWN  ;  Q5YS09, FPG_NOCFA  ;
DR   A1SLU7, FPG_NOCSJ  ;  B2J5G0, FPG_NOSP7  ;  Q8YP80, FPG_NOSS1  ;
DR   Q2GAT0, FPG_NOVAD  ;  Q8EPE6, FPG_OCEIH  ;  B6JCQ7, FPG_OLICO  ;
DR   A1BAN2, FPG_PARDP  ;  A7HZC4, FPG_PARL1  ;  Q6MCT3, FPG_PARUW  ;
DR   P57910, FPG_PASMU  ;  Q8VW76, FPG_PASPI  ;  C6DIB8, FPG_PECCP  ;
DR   Q03GC2, FPG_PEDPA  ;  Q3A3F2, FPG_PELCD  ;  A1AV29, FPG_PELPD  ;
DR   A5D0T6, FPG_PELTS  ;  B4RC43, FPG_PHEZH  ;  Q7MY36, FPG_PHOLL  ;
DR   Q6LVN0, FPG_PHOPR  ;  A1VKP2, FPG_POLNA  ;  B1XS61, FPG_POLNS  ;
DR   Q12DZ5, FPG_POLSJ  ;  A3PB53, FPG_PROM0  ;  A2C0H4, FPG_PROM1  ;
DR   A8G2Y9, FPG_PROM2  ;  A9BDY5, FPG_PROM4  ;  A2BUV8, FPG_PROM5  ;
DR   Q31CK0, FPG_PROM9  ;  Q7VDK6, FPG_PROMA  ;  B4F0X6, FPG_PROMH  ;
DR   Q7V8Y5, FPG_PROMM  ;  Q7V2X4, FPG_PROMP  ;  A2BPD1, FPG_PROMS  ;
DR   Q46H41, FPG_PROMT  ;  Q48CK1, FPG_PSE14  ;  Q15ZV5, FPG_PSEA6  ;
DR   A6UYG0, FPG_PSEA7  ;  B7V2S0, FPG_PSEA8  ;  Q02U58, FPG_PSEAB  ;
DR   Q9L7T2, FPG_PSEAE  ;  Q1IGF3, FPG_PSEE4  ;  Q4K4A5, FPG_PSEF5  ;
DR   C3K3N6, FPG_PSEFS  ;  A4Y028, FPG_PSEMY  ;  A5WAF9, FPG_PSEP1  ;
DR   Q3K566, FPG_PSEPF  ;  B0KN79, FPG_PSEPG  ;  Q88CQ5, FPG_PSEPK  ;
DR   B1J2M4, FPG_PSEPW  ;  Q88AH6, FPG_PSESM  ;  Q4ZM34, FPG_PSEU2  ;
DR   A4VRM9, FPG_PSEU5  ;  Q4FUU7, FPG_PSYA2  ;  A1SR12, FPG_PSYIN  ;
DR   Q1LRP7, FPG_RALME  ;  B2UES0, FPG_RALPJ  ;  Q8Y2D7, FPG_RALSO  ;
DR   B3PZ93, FPG_RHIE6  ;  Q2KDA9, FPG_RHIEC  ;  Q1MMD9, FPG_RHIL3  ;
DR   Q98BG6, FPG_RHILO  ;  B5ZYK9, FPG_RHILW  ;  Q59752, FPG_RHIME  ;
DR   C3MCY7, FPG_RHISN  ;  B6IVU4, FPG_RHOCS  ;  C0ZXQ5, FPG_RHOE4  ;
DR   Q21XW7, FPG_RHOFD  ;  C1B2Q5, FPG_RHOOB  ;  Q2J2I0, FPG_RHOP2  ;
DR   Q07UF4, FPG_RHOP5  ;  Q6NDM1, FPG_RHOPA  ;  Q21CD4, FPG_RHOPB  ;
DR   Q13EN7, FPG_RHOPS  ;  B3Q620, FPG_RHOPT  ;  Q2RMQ2, FPG_RHORT  ;
DR   A3PFL2, FPG_RHOS1  ;  Q3IY64, FPG_RHOS4  ;  A4WVR6, FPG_RHOS5  ;
DR   B9KQJ9, FPG_RHOSK  ;  Q0S2E0, FPG_RHOSR  ;  C3PLF5, FPG_RICAE  ;
DR   A8GXR0, FPG_RICB8  ;  Q1RJY6, FPG_RICBR  ;  A8EZP5, FPG_RICCK  ;
DR   Q92GT4, FPG_RICCN  ;  Q4UMW5, FPG_RICFE  ;  A8F2H0, FPG_RICM5  ;
DR   C4K2K4, FPG_RICPU  ;  B0BUU0, FPG_RICRO  ;  A8GTA0, FPG_RICRS  ;
DR   A7NQM8, FPG_ROSCS  ;  Q16DL0, FPG_ROSDO  ;  A5UUN1, FPG_ROSS1  ;
DR   A1AW02, FPG_RUTMC  ;  Q21EE3, FPG_SACD2  ;  A4FMJ7, FPG_SACEN  ;
DR   B5EXE0, FPG_SALA4  ;  A8M661, FPG_SALAI  ;  A9MKN9, FPG_SALAR  ;
DR   Q57IA7, FPG_SALCH  ;  B5FM59, FPG_SALDC  ;  B5R5F9, FPG_SALEP  ;
DR   B5RGF2, FPG_SALG2  ;  B4T9C0, FPG_SALHS  ;  B4SXD7, FPG_SALNS  ;
DR   Q5PC09, FPG_SALPA  ;  A9MVN0, FPG_SALPB  ;  C0Q1W8, FPG_SALPC  ;
DR   B5BI09, FPG_SALPK  ;  B4TZX7, FPG_SALSV  ;  Q8Z2H2, FPG_SALTI  ;
DR   A4X4F8, FPG_SALTO  ;  O54326, FPG_SALTY  ;  Q9X981, FPG_SERMA  ;
DR   A8GLE2, FPG_SERP5  ;  A1S1S3, FPG_SHEAM  ;  B8EDQ9, FPG_SHEB2  ;
DR   A3CYP7, FPG_SHEB5  ;  A6WUE9, FPG_SHEB8  ;  A9KW47, FPG_SHEB9  ;
DR   Q12SR9, FPG_SHEDO  ;  B0TN04, FPG_SHEHH  ;  A3QJA8, FPG_SHELP  ;
DR   Q8E8D9, FPG_SHEON  ;  A8HA27, FPG_SHEPA  ;  B8CVD1, FPG_SHEPW  ;
DR   A0L2N2, FPG_SHESA  ;  Q0HDC3, FPG_SHESM  ;  Q0HPK4, FPG_SHESR  ;
DR   A1RE25, FPG_SHESW  ;  B1KL38, FPG_SHEWM  ;  B2TTU9, FPG_SHIB3  ;
DR   Q31UZ1, FPG_SHIBS  ;  Q329M2, FPG_SHIDS  ;  Q0SYG3, FPG_SHIF8  ;
DR   P64149, FPG_SHIFL  ;  Q3YVZ7, FPG_SHISS  ;  Q5LWT9, FPG_SILPO  ;
DR   Q1GC55, FPG_SILST  ;  A6UFF8, FPG_SINMW  ;  Q2NQU4, FPG_SODGM  ;
DR   Q01RU9, FPG_SOLUE  ;  Q1GN82, FPG_SPHAL  ;  A5VG06, FPG_SPHWW  ;
DR   Q3K028, FPG_STRA1  ;  P64152, FPG_STRA3  ;  P64153, FPG_STRA5  ;
DR   Q82JU0, FPG_STRAW  ;  Q9ZBQ6, FPG_STRCO  ;  B1VYY1, FPG_STRGG  ;
DR   B4SRN0, FPG_STRM5  ;  B2FU49, FPG_STRMK  ;  P55045, FPG_STRMU  ;
DR   Q9A131, FPG_STRP1  ;  P0DB14, FPG_STRP3  ;  Q5XDE4, FPG_STRP6  ;
DR   Q8P250, FPG_STRP8  ;  Q48UU6, FPG_STRPM  ;  Q97R61, FPG_STRPN  ;
DR   P0DB15, FPG_STRPQ  ;  Q8DQ33, FPG_STRR6  ;  Q5M0P0, FPG_STRT1  ;
DR   Q5M576, FPG_STRT2  ;  Q67R59, FPG_SYMTH  ;  P95744, FPG_SYNEN  ;
DR   Q08079, FPG_SYNP6  ;  Q7U4V2, FPG_SYNPX  ;  Q0AVE3, FPG_SYNWW  ;
DR   P74290, FPG_SYNY3  ;  C5BLG1, FPG_TERTT  ;  P59065, FPG_THEEB  ;
DR   Q47S77, FPG_THEFY  ;  B9L1Z5, FPG_THERP  ;  Q72HN2, FPG_THET2  ;
DR   O50606, FPG_THET8  ;  Q31EB2, FPG_THICR  ;  Q3SLR9, FPG_THIDA  ;
DR   B8GUQ6, FPG_THISH  ;  Q117D2, FPG_TRIEI  ;  Q9PQ76, FPG_UREPA  ;
DR   C5CYZ1, FPG_VARPS  ;  A5CX90, FPG_VESOH  ;  A5F407, FPG_VIBC3  ;
DR   Q9KVC5, FPG_VIBCH  ;  C3LQI3, FPG_VIBCM  ;  Q5E8M1, FPG_VIBF1  ;
DR   B5FFG1, FPG_VIBFM  ;  A7MSN3, FPG_VIBHB  ;  Q87T81, FPG_VIBPA  ;
DR   B7VHK6, FPG_VIBSL  ;  Q8DDY4, FPG_VIBVU  ;  Q7MPS3, FPG_VIBVY  ;
DR   Q73G10, FPG_WOLPM  ;  B3CM71, FPG_WOLPP  ;  Q5GS47, FPG_WOLTR  ;
DR   C0R4I6, FPG_WOLWR  ;  Q8PEQ4, FPG_XANAC  ;  Q3BM92, FPG_XANC5  ;
DR   Q4UNU6, FPG_XANC8  ;  B0RZ50, FPG_XANCB  ;  Q8P3C4, FPG_XANCP  ;
DR   Q2P8V2, FPG_XANOM  ;  B2STU3, FPG_XANOP  ;  Q5H667, FPG_XANOR  ;
DR   A7IKJ3, FPG_XANP2  ;  P64154, FPG_XYLFA  ;  P64155, FPG_XYLFT  ;
DR   A1JHR7, FPG_YERE8  ;  A7FCT7, FPG_YERP3  ;  Q1C270, FPG_YERPA  ;
DR   B2JYN6, FPG_YERPB  ;  Q8ZJP0, FPG_YERPE  ;  A9R677, FPG_YERPG  ;
DR   Q1CD05, FPG_YERPN  ;  A4TSD4, FPG_YERPP  ;  Q66GD3, FPG_YERPS  ;
DR   B1JQX0, FPG_YERPY  ;  Q9X3X1, FPG_ZYMMO  ;  Q96FI4, NEIL1_HUMAN;
DR   Q8K4Q6, NEIL1_MOUSE;  Q6IE77, NEIL2_BOVIN;  Q969S2, NEIL2_HUMAN;
DR   Q6R2P8, NEIL2_MOUSE;  Q5RAJ7, NEIL2_PONAB;  Q3MHN7, NEIL3_BOVIN;
DR   Q8TAT5, NEIL3_HUMAN;  Q8K203, NEIL3_MOUSE;  P54137, NTH1_CAEEL ;
DR   Q8SRB8, NTH1_ENCCU ;  Q09907, NTH1_SCHPO ;  Q2KID2, NTHL1_BOVIN;
DR   P78549, NTHL1_HUMAN;  O35980, NTHL1_MOUSE;  O66612, OGG1_AQUAE ;
DR   O29876, OGG1_ARCFU ;  Q9V3I8, OGG1_DROME ;  Q8R689, OGG1_FUSNN ;
DR   O15527, OGG1_HUMAN ;  B1L640, OGG1_KORCO ;  Q58134, OGG1_METJA ;
DR   A4YHC9, OGG1_METS5 ;  O27397, OGG1_METTH ;  O08760, OGG1_MOUSE ;
DR   Q6L1T6, OGG1_PICTO ;  O70249, OGG1_RAT   ;  Q4J929, OGG1_SULAC ;
DR   C3N5H5, OGG1_SULIA ;  C4KH41, OGG1_SULIK ;  C3MPU9, OGG1_SULIL ;
DR   C3MUW1, OGG1_SULIM ;  C3NHM4, OGG1_SULIN ;  C3NE39, OGG1_SULIY ;
DR   Q97ZK2, OGG1_SULSO ;  Q972A8, OGG1_SULTO ;  Q9HM55, OGG1_THEAC ;
DR   Q9X2E1, OGG1_THEMA ;  B9K7J6, OGG1_THENN ;  A5ILP7, OGG1_THEP1 ;
DR   B1LAK2, OGG1_THESQ ;  Q97CP1, OGG1_THEVO ;  P53397, OGG1_YEAST ;
DR   P19889, RLA0_DROME ;  P27864, RRP1_DROME ;  P64158, Y2464_MYCTU;
DR   P64159, Y2491_MYCBO;  P64156, Y3297_MYCTU;  P64157, Y3325_MYCBO;
DR   O86820, Y5760_STRCO;
//
ID   4.2.99.19
DE   Transferred entry: 4.4.1.23.
//
ID   4.2.99.20
DE   2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase.
AN   2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase.
AN   6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase.
AN   SHCHC synthase.
CA   5-enolpyruvoyl-6-hydroxy-2-succinylcyclohex-3-ene-1-carboxylate =
CA   (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate + pyruvate.
CC   -!- Involved in the biosynthesis of vitamin K2 (menaquinone).
CC   -!- In most anaerobes and all Gram-positive aerobes, menaquinone is the
CC       sole electron transporter in the respiratory chain and is essential
CC       for their survival.
CC   -!- It had previously been thought that the reactions carried out by this
CC       enzyme and EC 2.2.1.9 were carried out by a single enzyme but this
CC       has since been disproved.
CC   -!- Formerly EC 2.5.1.64 and EC 4.2.99.n1.
DR   A8ADX0, MENH_CITK8 ;  A7ZP82, MENH_ECO24 ;  B7UFS6, MENH_ECO27 ;
DR   B7MG31, MENH_ECO45 ;  B7LAS9, MENH_ECO55 ;  Q8XDX9, MENH_ECO57 ;
DR   B5YXQ7, MENH_ECO5E ;  B7NNU3, MENH_ECO7I ;  B7MXU6, MENH_ECO81 ;
DR   B7M5U6, MENH_ECO8A ;  C4ZUA6, MENH_ECOBW ;  B1X8X7, MENH_ECODH ;
DR   A8A2D1, MENH_ECOHS ;  A1ADB5, MENH_ECOK1 ;  Q0TFH8, MENH_ECOL5 ;
DR   Q8FFL2, MENH_ECOL6 ;  B1IXS3, MENH_ECOLC ;  P37355, MENH_ECOLI ;
DR   B7N5M9, MENH_ECOLU ;  B6I7K7, MENH_ECOSE ;  B1LLL8, MENH_ECOSM ;
DR   Q1R9F0, MENH_ECOUT ;  A4WCP8, MENH_ENT38 ;  A7MHU5, MENH_ENTS8 ;
DR   Q6D7W3, MENH_ERWCT ;  B7LM67, MENH_ESCF3 ;  B5XNX1, MENH_KLEP3 ;
DR   A6TBV7, MENH_KLEP7 ;  Q7N2K4, MENH_PHOLL ;  B5EZI7, MENH_SALA4 ;
DR   A9MJB7, MENH_SALAR ;  Q57M48, MENH_SALCH ;  B5FPE7, MENH_SALDC ;
DR   B5R2Y9, MENH_SALEP ;  B5RCD3, MENH_SALG2 ;  B4TBH5, MENH_SALHS ;
DR   B4SYY0, MENH_SALNS ;  Q5PN75, MENH_SALPA ;  A9N5A3, MENH_SALPB ;
DR   C0Q060, MENH_SALPC ;  B5BCN7, MENH_SALPK ;  B4TPJ1, MENH_SALSV ;
DR   Q8Z534, MENH_SALTI ;  Q8ZNE9, MENH_SALTY ;  A8GGZ0, MENH_SERP5 ;
DR   B2TW49, MENH_SHIB3 ;  Q31YJ4, MENH_SHIBS ;  Q32DS5, MENH_SHIDS ;
DR   Q0T2M0, MENH_SHIF8 ;  Q83QT4, MENH_SHIFL ;  Q3YZU3, MENH_SHISS ;
DR   A1JKU0, MENH_YERE8 ;  A7FGT3, MENH_YERP3 ;  Q1C6D8, MENH_YERPA ;
DR   B2K7Z2, MENH_YERPB ;  Q7CJ75, MENH_YERPE ;  A9R6I9, MENH_YERPG ;
DR   Q1CHT0, MENH_YERPN ;  A4TM07, MENH_YERPP ;  Q669C8, MENH_YERPS ;
DR   B1JH89, MENH_YERPY ;  Q15KI9, PHYLO_ARATH;
//
ID   4.2.99.21
DE   Isochorismate lyase.
AN   Isochorismate pyruvate lyase.
CA   Isochorismate = salicylate + pyruvate.
CC   -!- This enzyme is part of the pathway of salicylate formation from
CC       chorismate, and forms an integral part of pathways that produce
CC       salicylate-derived siderophores, such as pyochelin and
CC       yersiniabactin.
//
ID   4.2.99.n1
DE   Transferred entry: 4.2.99.20.
//
ID   4.3.1.1
DE   Aspartate ammonia-lyase.
AN   Aspartase.
AN   Fumaric aminase.
CA   L-aspartate = fumarate + NH(3).
PR   PROSITE; PDOC00147;
DR   P26899, ASPA_BACSU ;  Q59200, ASPA_CORGL ;  Q8XDS0, ASPA_ECO57 ;
DR   P0AC39, ASPA_ECOL6 ;  P0AC38, ASPA_ECOLI ;  P44324, ASPA_HAEIN ;
DR   Q9ZLI5, ASPA_HELPJ ;  P56149, ASPA_HELPY ;  Q9HTD7, ASPA_PSEAE ;
DR   P07346, ASPA_PSEFL ;  P33109, ASPA_SERMA ;  P0AC40, ASPA_SHIFL ;
//
ID   4.3.1.2
DE   Methylaspartate ammonia-lyase.
AN   Beta-methylaspartase.
CA   L-threo-3-methylaspartate = mesaconate + NH(3).
CF   Cobalamin.
DR   Q05514, MAAL_CLOTT ;
//
ID   4.3.1.3
DE   Histidine ammonia-lyase.
AN   Histidase.
AN   Histidinase.
AN   Histidine alpha-deaminase.
CA   L-histidine = urocanate + NH(3).
CC   -!- Member of the aromatic amino acid lyase family, other members of
CC       which are EC 4.3.1.23, EC 4.3.1.24 and EC 4.3.1.25.
CC   -!- Catalyzes the first step in the degradation of histidine and the
CC       product, urocanic acid, is further metabolized to glutamate.
PR   PROSITE; PDOC00424;
DR   Q556V9, HALL_DICDI ;  Q8RFC2, HUTH1_FUSNN;  Q8RDU4, HUTH2_FUSNN;
DR   A1TRE4, HUTH_ACIAC ;  Q1IRT8, HUTH_ACIBL ;  A5FZB9, HUTH_ACICJ ;
DR   Q9KWE4, HUTH_AGRRH ;  B9JDC0, HUTH_AGRRK ;  Q8U8Z7, HUTH_AGRT5 ;
DR   B9K288, HUTH_AGRVS ;  A6TSX0, HUTH_ALKMQ ;  A8MF64, HUTH_ALKOO ;
DR   B8J950, HUTH_ANAD2 ;  Q2IIV4, HUTH_ANADE ;  B4UC43, HUTH_ANASK ;
DR   Q5NZX8, HUTH_AROAE ;  A7ZAE4, HUTH_BACA2 ;  C3P4M2, HUTH_BACAA ;
DR   C3L982, HUTH_BACAC ;  A0RH39, HUTH_BACAH ;  Q81Y45, HUTH_BACAN ;
DR   B7JI80, HUTH_BACC0 ;  Q733H8, HUTH_BACC1 ;  B7ISJ2, HUTH_BACC2 ;
DR   C1EN93, HUTH_BACC3 ;  B7HCD0, HUTH_BACC4 ;  B7HKJ1, HUTH_BACC7 ;
DR   A7GR00, HUTH_BACCN ;  B9IUH0, HUTH_BACCQ ;  Q81AC6, HUTH_BACCR ;
DR   Q637H8, HUTH_BACCZ ;  Q9KBE6, HUTH_BACHD ;  Q6HFE9, HUTH_BACHK ;
DR   Q5WAZ6, HUTH_BACSK ;  P10944, HUTH_BACSU ;  A9VPT8, HUTH_BACWK ;
DR   Q6G3U8, HUTH_BARHE ;  Q6FZP9, HUTH_BARQU ;  A9IVW5, HUTH_BART1 ;
DR   A7YWP4, HUTH_BOVIN ;  Q89GV3, HUTH_BRAJA ;  A5EQB7, HUTH_BRASB ;
DR   A4YNK7, HUTH_BRASO ;  B2SD96, HUTH_BRUA1 ;  Q2YIL6, HUTH_BRUA2 ;
DR   Q579E8, HUTH_BRUAB ;  A9MCL0, HUTH_BRUC2 ;  A5VVJ6, HUTH_BRUO2 ;
DR   A9WVU3, HUTH_BRUSI ;  Q8FVB4, HUTH_BRUSU ;  B1YT80, HUTH_BURA4 ;
DR   Q1BHY5, HUTH_BURCA ;  B1JV50, HUTH_BURCC ;  A0K8U6, HUTH_BURCH ;
DR   B4EDX5, HUTH_BURCJ ;  Q0BDK6, HUTH_BURCM ;  A9AGP7, HUTH_BURM1 ;
DR   A3MLT7, HUTH_BURM7 ;  A2SA96, HUTH_BURM9 ;  Q62LJ6, HUTH_BURMA ;
DR   A3NXA3, HUTH_BURP0 ;  A3NBH0, HUTH_BURP6 ;  B2T2Y2, HUTH_BURPP ;
DR   Q63SH6, HUTH_BURPS ;  Q39EP0, HUTH_BURS3 ;  A4JG46, HUTH_BURVG ;
DR   Q20502, HUTH_CAEEL ;  B8H2S1, HUTH_CAUCN ;  P58082, HUTH_CAUCR ;
DR   B0SYU6, HUTH_CAUSK ;  A9WHT8, HUTH_CHLAA ;  B9LLY0, HUTH_CHLSY ;
DR   Q7P188, HUTH_CHRVO ;  A8AJ15, HUTH_CITK8 ;  Q891Q1, HUTH_CLOTE ;
DR   C1CWB4, HUTH_DEIDV ;  Q9RZ06, HUTH_DEIRA ;  Q6AKP3, HUTH_DESPS ;
DR   Q54JI7, HUTH_DICDI ;  A4W8B5, HUTH_ENT38 ;  Q5L310, HUTH_GEOKA ;
DR   C5D4K1, HUTH_GEOSW ;  A4IK90, HUTH_GEOTN ;  Q7NCB3, HUTH_GLOVI ;
DR   A9H863, HUTH_GLUDA ;  Q5FRR8, HUTH_GLUOX ;  B0R544, HUTH_HALS3 ;
DR   Q9HQD5, HUTH_HALSA ;  P42357, HUTH_HUMAN ;  Q0BZK2, HUTH_HYPNA ;
DR   Q5QV30, HUTH_IDILO ;  B5XZ79, HUTH_KLEP3 ;  A6T6L1, HUTH_KLEP7 ;
DR   Q5X5I5, HUTH_LEGPA ;  A5IBM2, HUTH_LEGPC ;  Q5ZVR0, HUTH_LEGPH ;
DR   Q5WWW8, HUTH_LEGPL ;  B9E7E0, HUTH_MACCJ ;  Q0AP92, HUTH_MARMM ;
DR   Q11E18, HUTH_MESSB ;  B8II08, HUTH_METNO ;  B0UQ15, HUTH_METS4 ;
DR   P35492, HUTH_MOUSE ;  Q1D6R1, HUTH_MYXXD ;  B2A3D9, HUTH_NATTJ ;
DR   A6WYU8, HUTH_OCHA4 ;  A1AZX9, HUTH_PARDP ;  B4RED8, HUTH_PHEZH ;
DR   Q7N296, HUTH_PHOLL ;  Q6LQ56, HUTH_PHOPR ;  Q15X40, HUTH_PSEA6 ;
DR   B7V3J1, HUTH_PSEA8 ;  Q02ER8, HUTH_PSEAB ;  Q9HU85, HUTH_PSEAE ;
DR   Q8VMR3, HUTH_PSEFS ;  Q3KJE6, HUTH_PSEPF ;  Q88CZ7, HUTH_PSEPK ;
DR   P21310, HUTH_PSEPU ;  Q87UM1, HUTH_PSESM ;  Q1Q9E4, HUTH_PSYCK ;
DR   A1STQ3, HUTH_PSYIN ;  A5WDR1, HUTH_PSYWF ;  Q8XW29, HUTH_RALSO ;
DR   P21213, HUTH_RAT   ;  Q983I0, HUTH_RHILO ;  O31197, HUTH_RHIME ;
DR   B6IWC6, HUTH_RHOCS ;  Q2RUU3, HUTH_RHORT ;  A3PK23, HUTH_RHOS1 ;
DR   Q3J289, HUTH_RHOS4 ;  B9KSW6, HUTH_RHOSK ;  Q162E2, HUTH_ROSDO ;
DR   B5F069, HUTH_SALA4 ;  A9MJE9, HUTH_SALAR ;  Q57RG6, HUTH_SALCH ;
DR   B5FP58, HUTH_SALDC ;  B5QX62, HUTH_SALEP ;  B5R758, HUTH_SALG2 ;
DR   B4TC45, HUTH_SALHS ;  B4SZJ4, HUTH_SALNS ;  Q5PG61, HUTH_SALPA ;
DR   A9MTJ1, HUTH_SALPB ;  C0PWX9, HUTH_SALPC ;  B5BC34, HUTH_SALPK ;
DR   B4TQT6, HUTH_SALSV ;  Q8Z896, HUTH_SALTI ;  Q8ZQQ9, HUTH_SALTY ;
DR   Q8EKJ4, HUTH_SHEON ;  A8HA91, HUTH_SHEPA ;  B8CGY5, HUTH_SHEPW ;
DR   A8G1S5, HUTH_SHESH ;  B1KP55, HUTH_SHEWM ;  Q5LRD8, HUTH_SILPO ;
DR   A9GFW6, HUTH_SORC5 ;  Q1GSH0, HUTH_SPHAL ;  A6TXF8, HUTH_STAA2 ;
DR   Q2FKP8, HUTH_STAA3 ;  Q2G2P7, HUTH_STAA8 ;  A5INP9, HUTH_STAA9 ;
DR   Q2YUR3, HUTH_STAAB ;  Q5HJY8, HUTH_STAAC ;  A6QD47, HUTH_STAAE ;
DR   P64415, HUTH_STAAM ;  P64416, HUTH_STAAN ;  Q6GKT7, HUTH_STAAR ;
DR   Q6GD82, HUTH_STAAS ;  A8YYT1, HUTH_STAAT ;  Q8NYY3, HUTH_STAAW ;
DR   Q4A173, HUTH_STAS1 ;  Q93TX3, HUTH_STIAU ;  Q82I33, HUTH_STRAW ;
DR   Q9EWW1, HUTH_STRCO ;  A8AZ70, HUTH_STRGC ;  P24221, HUTH_STRGR ;
DR   P58083, HUTH_STRP1 ;  P0DB74, HUTH_STRP3 ;  Q5X9K4, HUTH_STRP6 ;
DR   Q8NZ46, HUTH_STRP8 ;  A2RGS5, HUTH_STRPG ;  P0DB75, HUTH_STRPQ ;
DR   B5XIY2, HUTH_STRPZ ;  A3CL24, HUTH_STRSV ;  Q67JH4, HUTH_SYMTH ;
DR   Q9HLI6, HUTH_THEAC ;  Q8RBH4, HUTH_THETN ;  Q978N8, HUTH_THEVO ;
DR   Q73Q56, HUTH_TREDE ;  Q9KSQ4, HUTH_VIBCH ;  Q5E0C6, HUTH_VIBF1 ;
DR   B5ETN1, HUTH_VIBFM ;  Q87Q77, HUTH_VIBPA ;  Q8DA21, HUTH_VIBVU ;
DR   Q7MK58, HUTH_VIBVY ;  Q8PLZ8, HUTH_XANAC ;  Q4UTB9, HUTH_XANC8 ;
DR   B0RUX3, HUTH_XANCB ;  Q8PAA7, HUTH_XANCP ;  A1JSW6, HUTH_YERE8 ;
DR   Q8ZA10, HUTH_YERPE ;  Q664B8, HUTH_YERPS ;  Q8YD09, HUTIH_BRUME;
//
ID   4.3.1.4
DE   Formimidoyltetrahydrofolate cyclodeaminase.
AN   Formiminotetrahydrofolate cyclodeaminase.
CA   5-formimidoyltetrahydrofolate = 5,10-methenyltetrahydrofolate + NH(3).
CC   -!- In eukaroytes, occurs as a bifunctional enzyme that also has
CC       EC 2.1.2.5 activity.
DR   Q9YH58, FTCD_CHICK ;  Q54JL3, FTCD_DICDI ;  O95954, FTCD_HUMAN ;
DR   Q91XD4, FTCD_MOUSE ;  P53603, FTCD_PIG   ;  O88618, FTCD_RAT   ;
//
ID   4.3.1.5
DE   Transferred entry: 4.3.1.23, 4.3.1.24 and 4.3.1.25.
//
ID   4.3.1.6
DE   Beta-alanyl-CoA ammonia-lyase.
CA   Beta-alanyl-CoA = acryloyl-CoA + NH(3).
//
ID   4.3.1.7
DE   Ethanolamine ammonia-lyase.
CA   Ethanolamine = acetaldehyde + NH(3).
CF   Cobalamin.
DR   P0AEJ7, EUTB_ECO57 ;  P0AEJ6, EUTB_ECOLI ;  P19264, EUTB_SALTY ;
DR   C1DNK9, EUTC_AZOVD ;  Q89QX6, EUTC_BRAJA ;  Q97FL9, EUTC_CLOAB ;
DR   Q187M6, EUTC_CLOD6 ;  Q0TSP9, EUTC_CLOP1 ;  Q8XLZ1, EUTC_CLOPE ;
DR   A9KMZ5, EUTC_CLOPH ;  Q892D0, EUTC_CLOTE ;  A7ZPP0, EUTC_ECO24 ;
DR   B7MHU1, EUTC_ECO45 ;  B7LCI4, EUTC_ECO55 ;  Q8XEH3, EUTC_ECO57 ;
DR   B5YZY5, EUTC_ECO5E ;  B7NPX6, EUTC_ECO7I ;  B7MXU7, EUTC_ECO81 ;
DR   B7M7E9, EUTC_ECO8A ;  C4ZX13, EUTC_ECOBW ;  B1XAB1, EUTC_ECODH ;
DR   A8A2T8, EUTC_ECOHS ;  A1ADV4, EUTC_ECOK1 ;  Q0TF29, EUTC_ECOL5 ;
DR   Q8FFA1, EUTC_ECOL6 ;  B1IWM2, EUTC_ECOLC ;  P19636, EUTC_ECOLI ;
DR   B7N630, EUTC_ECOLU ;  B6I516, EUTC_ECOSE ;  B1LMN4, EUTC_ECOSM ;
DR   Q1R8T1, EUTC_ECOUT ;  Q834L8, EUTC_ENTFA ;  B7LKJ3, EUTC_ESCF3 ;
DR   Q8RH35, EUTC_FUSNN ;  Q92CN1, EUTC_LISIN ;  C1L282, EUTC_LISMC ;
DR   Q720Q2, EUTC_LISMF ;  B8DC56, EUTC_LISMH ;  Q8Y7U4, EUTC_LISMO ;
DR   A0AHS0, EUTC_LISW6 ;  Q7N2V3, EUTC_PHOLL ;  A6V082, EUTC_PSEA7 ;
DR   B7V7T3, EUTC_PSEA8 ;  Q02SJ2, EUTC_PSEAB ;  Q9HX02, EUTC_PSEAE ;
DR   Q1IFI3, EUTC_PSEE4 ;  Q4K5E1, EUTC_PSEF5 ;  C3K2P6, EUTC_PSEFS ;
DR   A5VXY9, EUTC_PSEP1 ;  Q3K675, EUTC_PSEPF ;  B0KL94, EUTC_PSEPG ;
DR   Q88QF2, EUTC_PSEPK ;  B1J153, EUTC_PSEPW ;  Q889M3, EUTC_PSESM ;
DR   Q8XUR0, EUTC_RALSO ;  Q59782, EUTC_RHOER ;  Q07QM9, EUTC_RHOP5 ;
DR   B3QHD0, EUTC_RHOPT ;  B5F0I6, EUTC_SALA4 ;  A9MIC6, EUTC_SALAR ;
DR   B5FQF0, EUTC_SALDC ;  B5R4G5, EUTC_SALEP ;  B5RCS8, EUTC_SALG2 ;
DR   B4TCI7, EUTC_SALHS ;  B4T0I5, EUTC_SALNS ;  Q5PI32, EUTC_SALPA ;
DR   A9N329, EUTC_SALPB ;  C0PZ83, EUTC_SALPC ;  B5BB46, EUTC_SALPK ;
DR   B4TR32, EUTC_SALSV ;  Q8Z4U3, EUTC_SALTI ;  P19265, EUTC_SALTY ;
DR   Q32DB3, EUTC_SHIDS ;  Q3YZA3, EUTC_SHISS ;  Q8PK11, EUTC_XANAC ;
DR   Q4UVK6, EUTC_XANC8 ;  B0RS35, EUTC_XANCB ;  Q8P8I0, EUTC_XANCP ;
//
ID   4.3.1.8
DE   Transferred entry: 2.5.1.61.
//
ID   4.3.1.9
DE   Glucosaminate ammonia-lyase.
AN   2-amino-2-deoxy-D-gluconate ammonia-lyase.
AN   2-amino-2-deoxy-D-gluconate hydro-lyase (deaminating).
AN   Acetylenemonocarboxylic acid hydrase.
AN   Aminodeoxygluconate ammonia-lyase.
AN   Aminodeoxygluconate dehydratase.
AN   D-glucosaminate dehydratase.
AN   D-glucosaminic acid dehydrase.
AN   Glucosaminic dehydrase.
CA   D-glucosaminate = 2-dehydro-3-deoxy-D-gluconate + NH(3).
CF   Pyridoxal 5'-phosphate.
CC   -!- Formerly EC 4.2.1.26 and EC 4.3.1.21.
//
ID   4.3.1.10
DE   Serine-sulfate ammonia-lyase.
CA   L-serine O-sulfate + H(2)O = pyruvate + NH(3) + sulfate.
//
ID   4.3.1.11
DE   Deleted entry.
//
ID   4.3.1.12
DE   Ornithine cyclodeaminase.
AN   OCD.
AN   Ornithine cyclase.
AN   Ornithine cyclase (deaminating).
CA   L-ornithine = L-proline + NH(3).
CF   NAD.
CC   -!- The enzyme is a member of the mu-crystallin protein family.
CC   -!- The reaction is stimulated by the presence of ADP or ATP and is
CC       inhibited by O(2).
DR   P58338, OCD1_RHIME ;  P58339, OCD2_RHIME ;  Q59701, OCD_AGRT4  ;
DR   P09773, OCD_AGRT5  ;  Q59175, OCD_BRUAB  ;  Q8YCY1, OCD_BRUME  ;
DR   Q8FVE4, OCD_BRUSU  ;  P33728, OCD_RHIME  ;
//
ID   4.3.1.13
DE   Carbamoyl-serine ammonia-lyase.
AN   O-carbamoyl-L-serine deaminase.
CA   O-carbamoyl-L-serine + H(2)O = pyruvate + 2 NH(3) + CO(2).
CF   Pyridoxal 5'-phosphate.
//
ID   4.3.1.14
DE   3-aminobutyryl-CoA ammonia-lyase.
AN   L-3-aminobutyryl-CoA deaminase.
CA   L-3-aminobutyryl-CoA = crotonoyl-CoA + NH(3).
CC   -!- Hydroxylamine can replace ammonia as a substrate.
CC   -!- Crotonoyl-pantetheine can replace crotonoyl-CoA but it is a poorer
CC       substrate.
//
ID   4.3.1.15
DE   Diaminopropionate ammonia-lyase.
AN   2,3-diaminopropanoate ammonia-lyase.
AN   Alpha,beta-diaminopropionate ammonia-lyase.
AN   Diaminopropionatase.
CA   2,3-diaminopropionate + H(2)O = pyruvate + 2 NH(3).
CF   Pyridoxal 5'-phosphate.
CC   -!- Active toward both D- and L-diaminopropionate.
CC   -!- D- and L-serine are poor substrates.
DR   P66901, DPAL_ECO57 ;  P66900, DPAL_ECOL6 ;  P66899, DPAL_ECOLI ;
DR   P40817, DPAL_SALTY ;
//
ID   4.3.1.16
DE   Threo-3-hydroxy-L-aspartate ammonia-lyase.
AN   L-threo-3-hydroxyaspartate dehydratase.
AN   Threo-3-hydroxyaspartate dehydratase.
CA   Threo-3-hydroxy-L-aspartate = oxaloacetate + NH(3).
CF   Pyridoxal 5'-phosphate.
CC   -!- The enzyme, purified from the bacterium Pseudomonas sp. T62,
CC       is highly specific, and does not accept any other stereoisomer of
CC       3-hydroxyaspartate.
CC   -!- Different from EC 4.3.1.20 and EC 4.3.1.27.
CC   -!- Requires a divalent cation such as Mn(2+), Mg(2+), or Ca(2+).
DR   P36007, SRY1_YEAST ;
//
ID   4.3.1.17
DE   L-serine ammonia-lyase.
AN   L-hydroxyaminoacid dehydratase.
AN   L-serine deaminase.
AN   L-serine dehydratase.
AN   L-serine hydro-lyase (deaminating).
AN   Serine deaminase.
CA   L-serine = pyruvate + NH(3).
CF   Pyridoxal 5'-phosphate.
CC   -!- This reaction is also carried out by EC 4.3.1.19 from a number of
CC       sources.
CC   -!- The reaction catalyzed probably involves initial elimination of water
CC       (hence the enzyme's original classification as EC 4.2.1.13), followed
CC       by isomerization and hydrolysis of the product with C-N bond
CC       breakage.
CC   -!- Formerly EC 4.2.1.13.
PR   PROSITE; PDOC00149;
DR   P0CF21, SDH1_YEAST ;  P0CF23, SDH1_YEASX ;  O34607, SDHA_BACSU ;
DR   P80212, SDHA_CLOPR ;  Q48838, SDHA_LACSK ;  P33073, SDHA_PEPAS ;
DR   O34635, SDHB_BACSU ;  P80213, SDHB_CLOPR ;  P33074, SDHB_PEPAS ;
DR   Q0VCW4, SDHL_BOVIN ;  Q86B06, SDHL_DICDI ;  P16095, SDHL_ECOLI ;
DR   P71349, SDHL_HAEIN ;  Q9ZMU7, SDHL_HELPJ ;  P56072, SDHL_HELPY ;
DR   P20132, SDHL_HUMAN ;  Q8VBT2, SDHL_MOUSE ;  P66774, SDHL_MYCBO ;
DR   P66773, SDHL_MYCTU ;  P09367, SDHL_RAT   ;  O86564, SDHL_STRCO ;
DR   B3LU13, SDHL_YEAS1 ;  B5VKE8, SDHL_YEAS6 ;  A6ZVB1, SDHL_YEAS7 ;
DR   C8ZAU6, SDHL_YEAS8 ;  P30744, SDHM_ECOLI ;  Q96GA7, SDSL_HUMAN ;
DR   Q8R238, SDSL_MOUSE ;  A0JNI4, SRR_BOVIN  ;  Q54HH2, SRR_DICDI  ;
DR   Q9GZT4, SRR_HUMAN  ;  Q9QZX7, SRR_MOUSE  ;  Q76EQ0, SRR_RAT    ;
DR   O59791, SRR_SCHPO  ;  P25379, STDH_YEAST ;  P42630, TDCG_ECOLI ;
//
ID   4.3.1.18
DE   D-serine ammonia-lyase.
AN   D-hydroxy amino acid dehydratase.
AN   D-serine deaminase.
AN   D-serine dehydrase.
AN   D-serine dehydratase.
AN   D-serine dehydratase (deaminating).
AN   D-serine hydro-lyase (deaminating).
AN   D-serine hydrolase.
CA   D-serine = pyruvate + NH(3).
CF   Pyridoxal 5'-phosphate.
CC   -!- Also acts, slowly, on D-threonine.
CC   -!- The reaction catalyzed probably involves initial elimination of water
CC       (hence the enzyme's original classification as EC 4.2.1.14), followed
CC       by isomerization and hydrolysis of the product with C-N bond
CC       breakage.
CC   -!- Formerly EC 4.2.1.14.
DR   Q9US35, DSD1_SCHPO ;  P53095, DSD1_YEAST ;  Q0TF95, SDHD1_ECOL5;
DR   Q1R901, SDHD1_ECOUT;  Q0T953, SDHD2_ECOL5;  Q1R2Q6, SDHD2_ECOUT;
DR   A1TPW5, SDHD_ACIAC ;  Q6FDC1, SDHD_ACIAD ;  B7I8P7, SDHD_ACIB5 ;
DR   B2HVC6, SDHD_ACIBC ;  A3M3B1, SDHD_ACIBT ;  B9MIR7, SDHD_ACIET ;
DR   A1W838, SDHD_ACISJ ;  A0KI76, SDHD_AERHH ;  A4SPX2, SDHD_AERS4 ;
DR   C3L7G5, SDHD_BACAC ;  A0RCF8, SDHD_BACAH ;  Q81S85, SDHD_BACAN ;
DR   Q73AC5, SDHD_BACC1 ;  B7IR88, SDHD_BACC2 ;  C1EPF1, SDHD_BACC3 ;
DR   B7HID8, SDHD_BACC4 ;  B7HMG6, SDHD_BACC7 ;  Q81F73, SDHD_BACCR ;
DR   Q63D23, SDHD_BACCZ ;  Q9KC12, SDHD_BACHD ;  Q6HKG3, SDHD_BACHK ;
DR   Q5WGL6, SDHD_BACSK ;  P54555, SDHD_BACSU ;  A9VPH9, SDHD_BACWK ;
DR   A3P975, SDHD_BURP0 ;  Q3JJ76, SDHD_BURP1 ;  A3NNQ0, SDHD_BURP6 ;
DR   Q63IF8, SDHD_BURPS ;  Q396Y3, SDHD_BURS3 ;  Q2T8Q2, SDHD_BURTA ;
DR   Q3AFZ5, SDHD_CARHZ ;  Q7NUP9, SDHD_CHRVO ;  A8ACI7, SDHD_CITK8 ;
DR   Q47V69, SDHD_COLP3 ;  Q46X58, SDHD_CUPPJ ;  Q24WR0, SDHD_DESHY ;
DR   A7ZPH2, SDHD_ECO24 ;  B7MH26, SDHD_ECO45 ;  B7LBR9, SDHD_ECO55 ;
DR   Q8XCK5, SDHD_ECO57 ;  B5YYW7, SDHD_ECO5E ;  B7MY25, SDHD_ECO81 ;
DR   B7M6N5, SDHD_ECO8A ;  C4ZVQ3, SDHD_ECOBW ;  B1X9N9, SDHD_ECODH ;
DR   A8A2M0, SDHD_ECOHS ;  A1ADP3, SDHD_ECOK1 ;  Q8FFF4, SDHD_ECOL6 ;
DR   B1IX96, SDHD_ECOLC ;  P00926, SDHD_ECOLI ;  B7N5W6, SDHD_ECOLU ;
DR   B6I6R7, SDHD_ECOSE ;  B7LK20, SDHD_ESCF3 ;  Q8RFX6, SDHD_FUSNN ;
DR   Q75TC9, SDHD_GEOKA ;  Q75TH5, SDHD_GEOSE ;  Q0I5V1, SDHD_HAES1 ;
DR   B0UWV3, SDHD_HAES2 ;  Q2SHX7, SDHD_HAHCH ;  B2GBP8, SDHD_LACF3 ;
DR   Q88TY1, SDHD_LACPL ;  Q04G28, SDHD_OENOB ;  Q03DF6, SDHD_PEDPA ;
DR   Q7N5H9, SDHD_PHOLL ;  Q6LHF5, SDHD_PHOPR ;  A1VWK8, SDHD_POLNA ;
DR   A6V271, SDHD_PSEA7 ;  B7V2Y0, SDHD_PSEA8 ;  Q02QJ1, SDHD_PSEAB ;
DR   Q9HYN9, SDHD_PSEAE ;  A4XXF3, SDHD_PSEMY ;  A5W4Y8, SDHD_PSEP1 ;
DR   B0KGK3, SDHD_PSEPG ;  B3PYT5, SDHD_RHIE6 ;  B5ZNC1, SDHD_RHILW ;
DR   B5EY75, SDHD_SALA4 ;  A9MKH2, SDHD_SALAR ;  Q57I32, SDHD_SALCH ;
DR   B5FMC1, SDHD_SALDC ;  B5QU31, SDHD_SALEP ;  B5RG23, SDHD_SALG2 ;
DR   B4TA53, SDHD_SALHS ;  B4SY68, SDHD_SALNS ;  Q5PKR3, SDHD_SALPA ;
DR   A9MWI4, SDHD_SALPB ;  C0Q241, SDHD_SALPC ;  B5BII6, SDHD_SALPK ;
DR   B4TMW9, SDHD_SALSV ;  Q8Z2L4, SDHD_SALTI ;  Q8ZL08, SDHD_SALTY ;
DR   A8GES6, SDHD_SERP5 ;  Q31YA5, SDHD_SHIBS ;  Q32DH8, SDHD_SHIDS ;
DR   Q0T2D1, SDHD_SHIF8 ;  Q83MK8, SDHD_SHIFL ;  Q3YZG4, SDHD_SHISS ;
DR   A6UB95, SDHD_SINMW ;  Q4A041, SDHD_STAS1 ;  A5F0M6, SDHD_VIBC3 ;
DR   Q9KL72, SDHD_VIBCH ;  C3LWD9, SDHD_VIBCM ;  A7MYG2, SDHD_VIBHB ;
DR   Q87QA2, SDHD_VIBPA ;  A1JJW5, SDHD_YERE8 ;  A0JNI4, SRR_BOVIN  ;
DR   Q54HH2, SRR_DICDI  ;  Q9GZT4, SRR_HUMAN  ;  Q9QZX7, SRR_MOUSE  ;
DR   Q76EQ0, SRR_RAT    ;  O59791, SRR_SCHPO  ;
//
ID   4.3.1.19
DE   Threonine ammonia-lyase.
AN   L-serine dehydratase.
AN   L-threonine deaminase.
AN   L-threonine dehydratase.
AN   L-threonine hydro-lyase (deaminating).
AN   Serine deaminase.
AN   Threonine deaminase.
AN   Threonine dehydrase.
AN   Threonine dehydratase.
CA   L-threonine = 2-oxobutanoate + NH(3).
CF   Pyridoxal 5'-phosphate.
CC   -!- The protein from Pseudomonas putida does not require pyridoxal-
CC       phosphate.
CC   -!- The enzyme from a number of sources also acts on L-serine,
CC       cf. EC 4.3.1.17.
CC   -!- The reaction catalyzed probably involves initial elimination of water
CC       (hence the enzyme's original classification as EC 4.2.1.16), followed
CC       by isomerization and hydrolysis of the product with C-N bond
CC       breakage.
CC   -!- Formerly EC 4.2.1.16.
PR   PROSITE; PDOC00149;
DR   Q0VCW4, SDHL_BOVIN ;  P20132, SDHL_HUMAN ;  Q8VBT2, SDHL_MOUSE ;
DR   P09367, SDHL_RAT   ;  Q96GA7, SDSL_HUMAN ;  Q8R238, SDSL_MOUSE ;
DR   P25379, STDH_YEAST ;  Q9ZSS6, THD1_ARATH ;  Q9KC63, THD1_BACHD ;
DR   P37946, THD1_BACSU ;  P53607, THD1_BURM1 ;  Q39469, THD1_CICAR ;
DR   Q04513, THD1_CORGL ;  P04968, THD1_ECOLI ;  P46493, THD1_HAEIN ;
DR   Q02145, THD1_LACLA ;  P66898, THD1_MYCBO ;  Q9X7F1, THD1_MYCLE ;
DR   P66897, THD1_MYCTU ;  Q9CKJ2, THD1_PASMU ;  P20506, THD1_SALTY ;
DR   P25306, THD1_SOLLC ;  P31212, THD1_SOLTU ;  Q2FF63, THD1_STAA3 ;
DR   Q2FWJ9, THD1_STAA8 ;  Q2YUE8, THD1_STAAB ;  Q5HEE0, THD1_STAAC ;
DR   Q99SJ1, THD1_STAAM ;  Q7A4H2, THD1_STAAN ;  Q3V7T5, THD1_STAAR ;
DR   Q3V7T4, THD1_STAAS ;  Q8NVI8, THD1_STAAW ;  Q5HMF5, THD1_STAEQ ;
DR   Q8CNK9, THD1_STAES ;  Q4L7U4, THD1_STAHJ ;  Q49Z16, THD1_STAS1 ;
DR   P0AGF8, THD2_ECO57 ;  P0AGF7, THD2_ECOL6 ;  P0AGF6, THD2_ECOLI ;
DR   P11954, THD2_SALTY ;  P0AGF9, THD2_SHIFL ;  Q2FH01, THD2_STAA3 ;
DR   Q2FYJ3, THD2_STAA8 ;  Q2YY67, THD2_STAAB ;  Q5HFY5, THD2_STAAC ;
DR   Q99U50, THD2_STAAM ;  Q7A5L8, THD2_STAAN ;  Q6GGX0, THD2_STAAR ;
DR   Q6G9C4, THD2_STAAS ;  Q8NWQ4, THD2_STAAW ;  O42615, THDH_BLAAD ;
DR   O94634, THDH_SCHPO ;  P00927, THDH_YEAST ;  P55664, Y4TJ_RHISN ;
//
ID   4.3.1.20
DE   Erythro-3-hydroxy-L-aspartate ammonia-lyase.
AN   3-hydroxyaspartate dehydratase.
AN   Erythro-3-hydroxy-L(s)-aspartate hydro-lyase (deaminating).
AN   Erythro-3-hydroxyaspartate dehydratase.
AN   Erythro-beta-hydroxyaspartate dehydratase.
CA   Erythro-3-hydroxy-L-aspartate = oxaloacetate + NH(3).
CF   Pyridoxal 5'-phosphate.
CC   -!- The enzyme, which was characterized from the bacterium Paracoccus
CC       denitrificans NCIMB 8944, is highly specific for the L-isomer of
CC       erythro-3-hydroxyaspartate.
CC   -!- Different from EC 4.3.1.16 and EC 4.3.1.27.
CC   -!- Requires a divalent cation such as Mn(2+), Mg(2+), or Ca(2+).
CC   -!- Formerly EC 4.2.1.38.
//
ID   4.3.1.21
DE   Transferred entry: 4.3.1.9.
//
ID   4.3.1.22
DE   3,4-dihydroxyphenylalanine reductive deaminase.
AN   DOPA-reductive deaminase.
AN   DOPARDA.
AN   Reductive deaminase.
CA   3,4-dihydroxy-L-phenylalanine + NADH = 3,4-dihydroxyphenylpropanoate +
CA   NAD(+) + NH(3).
CC   -!- Forms part of the L-phenylalanine-catabolism pathway in the
CC       anoxygenic phototrophic bacterium Rhodobacter sphaeroides OU5.
CC   -!- NADPH is oxidized more slowly than NADH.
//
ID   4.3.1.23
DE   Tyrosine ammonia-lyase.
AN   L-tyrosine ammonia-lyase.
AN   TAL.
AN   Tyrase.
CA   L-tyrosine = trans-p-hydroxycinnamate + ammonia.
CF   MIO.
CC   -!- Member of the aromatic amino acid lyase family, other members of
CC       which are EC 4.3.1.3, EC 4.3.1.24 and EC 4.3.1.25.
CC   -!- Far more active with tyrosine than with phenylalanine as substrate,
CC       but the substrate specificity can be switched by mutation of a single
CC       amino acid (H89F) in the enzyme from the bacterium Rhodobacter
CC       sphaeroides.
CC   -!- Formerly EC 4.3.1.5.
PR   PROSITE; PDOC00424;
DR   Q1LRV9, TALY_RALME ;  Q0VZ68, TAM_CHOCO  ;  B8ZV93, TAM_MYXFU  ;
DR   B8ZV94, TAM_MYXSM  ;
//
ID   4.3.1.24
DE   Phenylalanine ammonia-lyase.
CA   L-phenylalanine = trans-cinnamate + ammonia.
CF   MIO.
CC   -!- Member of the aromatic amino acid lyase family, other members of
CC       which are EC 4.3.1.3 and EC 4.3.1.23 and EC 4.3.1.25.
CC   -!- The enzyme from some species is highly specific for phenylalanine.
CC   -!- Formerly EC 4.3.1.5.
PR   PROSITE; PDOC00424;
DR   P35510, PAL1_ARATH ;  O23865, PAL1_DAUCA ;  P14166, PAL1_IPOBA ;
DR   O49835, PAL1_LITER ;  P14717, PAL1_ORYSJ ;  Q01861, PAL1_PEA   ;
DR   P24481, PAL1_PETCR ;  P07218, PAL1_PHAVU ;  P45731, PAL1_POPKI ;
DR   O64963, PAL1_PRUAV ;  Q9M568, PAL1_RUBID ;  P35511, PAL1_SOLLC ;
DR   P31425, PAL1_SOLTU ;  P27991, PAL1_SOYBN ;  P25872, PAL1_TOBAC ;
DR   P45724, PAL2_ARATH ;  Q9SMK9, PAL2_CICAR ;  Q42858, PAL2_IPOBA ;
DR   O49836, PAL2_LITER ;  A2X7F7, PAL2_ORYSI ;  Q0DZE0, PAL2_ORYSJ ;
DR   Q04593, PAL2_PEA   ;  P45728, PAL2_PETCR ;  P19142, PAL2_PHAVU ;
DR   Q43052, PAL2_POPKI ;  P31426, PAL2_SOLTU ;  P35513, PAL2_TOBAC ;
DR   P45725, PAL3_ARATH ;  P45729, PAL3_PETCR ;  P19143, PAL3_PHAVU ;
DR   P45733, PAL3_TOBAC ;  Q9SS45, PAL4_ARATH ;  Q40910, PAL4_POPKI ;
DR   P26600, PAL5_SOLLC ;  Q92195, PALY_AGABI ;  O93967, PALY_AMAMU ;
DR   Q42609, PALY_BROFI ;  P45726, PALY_CAMSI ;  Q42667, PALY_CITLI ;
DR   O23924, PALY_DIGLA ;  O04058, PALY_HELAN ;  P35512, PALY_MALDO ;
DR   P27990, PALY_MEDSA ;  P45727, PALY_PERAE ;  P52777, PALY_PINTA ;
DR   P45730, PALY_POPTR ;  P10248, PALY_RHORB ;  P11544, PALY_RHOTO ;
DR   P45732, PALY_STYHU ;  P45734, PALY_TRISU ;  Q96V77, PALY_USTMA ;
DR   P45735, PALY_VITVI ;  Q43210, PALY_WHEAT ;
//
ID   4.3.1.25
DE   Phenylalanine/tyrosine ammonia-lyase.
AN   Bifunctional PAL.
AN   PTAL.
CA   (1) L-phenylalanine = trans-cinnamate + ammonia.
CA   (2) L-tyrosine = trans-p-hydroxycinnamate + ammonia.
CF   MIO.
CC   -!- Member of the aromatic amino acid lyase family, other members of
CC       which are EC 4.3.1.3, EC 4.3.1.23 and EC 4.3.1.24.
CC   -!- The enzyme from some monocots, including maize, and from the yeast
CC       Rhodosporidium toruloides, deaminate L-phenylalanine and L-tyrosine
CC       with similar catalytic efficiency.
CC   -!- Formerly EC 4.3.1.5.
PR   PROSITE; PDOC00424;
//
ID   4.3.1.26
DE   Chromopyrrolate synthase.
CA   2 2-imino-3-(7-chloroindol-3-yl)propanoate = dichlorochromopyrrolate +
CA   ammonium.
CF   Heme; Iron.
CC   -!- This enzyme catalyzes a step in the biosynthesis of rebeccamycin,
CC       an indolocarbazole alkaloid produced by the actinobacterium
CC       Lechevalieria aerocolonigenes.
CC   -!- The enzyme is a dimeric heme-protein oxidase that catalyzes the
CC       oxidative dimerization of two L-tryptophan-derived molecules to form
CC       dichlorochromopyrrolic acid, the precursor for the fused six-ring
CC       indolocarbazole scaffold of rebeccamycin.
//
ID   4.3.1.27
DE   Threo-3-hydroxy-D-aspartate ammonia-lyase.
AN   D-threo-3-hydroxyaspartate dehydratase.
CA   Threo-3-hydroxy-D-aspartate = oxaloacetate + NH(3).
CF   Pyridoxal 5'-phosphate.
CC   -!- The enzyme, purified from the bacterium Delftia sp. HT23, also has
CC       activity against L-threo-3-hydroxyaspartate, L-erythro-3-
CC       hydroxyaspartate, and D-serine.
CC   -!- Different from EC 4.3.1.20 and EC 4.3.1.16.
CC   -!- Requires a divalent cation such as Mn(2+), Co(2+) or Ni(2+).
//
ID   4.3.2.1
DE   Argininosuccinate lyase.
AN   Arginosuccinase.
AN   N-(L-argininosuccinate) arginine-lyase.
AN   Omega-N-(L-arginino)succinate arginine-lyase.
CA   2-(N(omega)-L-arginino)succinate = fumarate + L-arginine.
PR   PROSITE; PDOC00147;
DR   Q9K3D6, ARGHA_MORAB;  Q9K3D7, ARGHA_MORPR;  Q8U9X6, ARLY1_AGRT5;
DR   Q5WHY3, ARLY1_BACSK;  Q3KCB2, ARLY1_PSEPF;  Q98G36, ARLY1_RHILO;
DR   Q92MH1, ARLY1_RHIME;  Q8U705, ARLY2_AGRT5;  P24058, ARLY2_ANAPL;
DR   Q5WED9, ARLY2_BACSK;  P05083, ARLY2_CHICK;  Q3K4S8, ARLY2_PSEPF;
DR   Q981V0, ARLY2_RHILO;  Q92VM6, ARLY2_RHIME;  B0CEZ5, ARLY_ACAM1 ;
DR   A1TNJ5, ARLY_ACIAC ;  Q6FFB2, ARLY_ACIAD ;  B7H1L9, ARLY_ACIB3 ;
DR   B7I338, ARLY_ACIB5 ;  B2I1W9, ARLY_ACIBC ;  Q1IIZ3, ARLY_ACIBL ;
DR   B0VMC7, ARLY_ACIBS ;  B0VDE4, ARLY_ACIBY ;  A0LUB8, ARLY_ACIC1 ;
DR   C1F4E8, ARLY_ACIC5 ;  A5FWI3, ARLY_ACICJ ;  B9MDU0, ARLY_ACIET ;
DR   A1WB09, ARLY_ACISJ ;  A3N1I1, ARLY_ACTP2 ;  B3GY67, ARLY_ACTP7 ;
DR   B0BQC2, ARLY_ACTPJ ;  A6VKY5, ARLY_ACTSZ ;  A0KFV4, ARLY_AERHH ;
DR   A4SIM6, ARLY_AERS4 ;  B9JTJ2, ARLY_AGRVS ;  Q0VM25, ARLY_ALCBS ;
DR   Q0A574, ARLY_ALHEH ;  A6TL09, ARLY_ALKMQ ;  B4S0H4, ARLY_ALTMD ;
DR   B8JAN8, ARLY_ANAD2 ;  Q2IGX8, ARLY_ANADE ;  A7H771, ARLY_ANADF ;
DR   B4UHY4, ARLY_ANASK ;  B9MRP4, ARLY_ANATD ;  Q3MC57, ARLY_ANAVT ;
DR   B7GGR5, ARLY_ANOFW ;  P33110, ARLY_ANSAN ;  O67383, ARLY_AQUAE ;
DR   A8ESF7, ARLY_ARCB4 ;  O29379, ARLY_ARCFU ;  Q5P7H3, ARLY_AROAE ;
DR   A1K451, ARLY_AZOSB ;  C1DJ48, ARLY_AZOVD ;  A7Z7L9, ARLY_BACA2 ;
DR   C3PB96, ARLY_BACAA ;  C3L913, ARLY_BACAC ;  A0RJM3, ARLY_BACAH ;
DR   Q81KV8, ARLY_BACAN ;  B7JS05, ARLY_BACC0 ;  Q72ZA4, ARLY_BACC1 ;
DR   B7IK28, ARLY_BACC2 ;  B7H6Y4, ARLY_BACC4 ;  B7HRS6, ARLY_BACC7 ;
DR   A7GTR4, ARLY_BACCN ;  Q817C7, ARLY_BACCR ;  Q633G5, ARLY_BACCZ ;
DR   Q5LI10, ARLY_BACFN ;  Q64Z15, ARLY_BACFR ;  Q9K821, ARLY_BACHD ;
DR   Q6HCP8, ARLY_BACHK ;  Q65G68, ARLY_BACLD ;  A8FG69, ARLY_BACP2 ;
DR   O34858, ARLY_BACSU ;  Q8A1D3, ARLY_BACTN ;  A6KYN9, ARLY_BACV8 ;
DR   A9VKE0, ARLY_BACWK ;  A1UQY9, ARLY_BARBK ;  A9IZG7, ARLY_BART1 ;
DR   B3DSY6, ARLY_BIFLD ;  Q8G5F3, ARLY_BIFLO ;  B7GTN9, ARLY_BIFLS ;
DR   Q2L1J6, ARLY_BORA1 ;  Q7WJI7, ARLY_BORBR ;  Q7WAE4, ARLY_BORPA ;
DR   Q7VVG6, ARLY_BORPE ;  Q3SZJ0, ARLY_BOVIN ;  P59613, ARLY_BRAJA ;
DR   A5EB50, ARLY_BRASB ;  A4Z1S4, ARLY_BRASO ;  B2S8N8, ARLY_BRUA1 ;
DR   Q2YR87, ARLY_BRUA2 ;  Q57AS3, ARLY_BRUAB ;  A9M968, ARLY_BRUC2 ;
DR   C0RFM4, ARLY_BRUMB ;  Q8YJJ7, ARLY_BRUME ;  B0CIY4, ARLY_BRUSI ;
DR   Q8FYA4, ARLY_BRUSU ;  P57159, ARLY_BUCAI ;  Q8KA59, ARLY_BUCAP ;
DR   P59614, ARLY_BUCBP ;  Q058D5, ARLY_BUCCC ;  Q1BUI4, ARLY_BURCA ;
DR   B1JWR5, ARLY_BURCC ;  A0K9K2, ARLY_BURCH ;  B4E8D2, ARLY_BURCJ ;
DR   P59615, ARLY_BURM1 ;  A3MLL6, ARLY_BURM7 ;  A2SAG6, ARLY_BURM9 ;
DR   Q62LD1, ARLY_BURMA ;  A1V5V1, ARLY_BURMS ;  B2JEP3, ARLY_BURP8 ;
DR   B2T1C7, ARLY_BURPP ;  Q39DW2, ARLY_BURS3 ;  Q2T079, ARLY_BURTA ;
DR   A4JGV8, ARLY_BURVG ;  Q143B9, ARLY_BURXL ;  A4XKG3, ARLY_CALS8 ;
DR   A7ZC90, ARLY_CAMC1 ;  A7GXA8, ARLY_CAMC5 ;  A7I3C8, ARLY_CAMHC ;
DR   A8FLY0, ARLY_CAMJ8 ;  A7H3C0, ARLY_CAMJD ;  Q46104, ARLY_CAMJE ;
DR   A1VZR4, ARLY_CAMJJ ;  Q5HUM8, ARLY_CAMJR ;  P43061, ARLY_CANAL ;
DR   Q3A9W6, ARLY_CARHZ ;  Q9A683, ARLY_CAUCR ;  B0T2T7, ARLY_CAUSK ;
DR   A9WJR8, ARLY_CHLAA ;  B8GD12, ARLY_CHLAD ;  Q3ASM4, ARLY_CHLCH ;
DR   B3ECP3, ARLY_CHLL2 ;  B3QN90, ARLY_CHLP8 ;  A1BG31, ARLY_CHLPD ;
DR   P22675, ARLY_CHLRE ;  B9LD91, ARLY_CHLSY ;  Q8KDJ5, ARLY_CHLTE ;
DR   Q1QSV4, ARLY_CHRSD ;  Q7P1U7, ARLY_CHRVO ;  A8AKW2, ARLY_CITK8 ;
DR   A5CSI8, ARLY_CLAM3 ;  B0RHD6, ARLY_CLAMS ;  Q97KE5, ARLY_CLOAB ;
DR   A7FWU5, ARLY_CLOB1 ;  C3L1U2, ARLY_CLOB6 ;  A6M1Z5, ARLY_CLOB8 ;
DR   B2UYI1, ARLY_CLOBA ;  B2TQ24, ARLY_CLOBB ;  A5I5A3, ARLY_CLOBH ;
DR   C1FU67, ARLY_CLOBJ ;  B1IK07, ARLY_CLOBK ;  A7GGQ8, ARLY_CLOBL ;
DR   B1KXY0, ARLY_CLOBM ;  B8I1A0, ARLY_CLOCE ;  Q182I5, ARLY_CLOD6 ;
DR   B9E0B2, ARLY_CLOK1 ;  A5N6U3, ARLY_CLOK5 ;  A0Q1Z1, ARLY_CLONN ;
DR   Q0TTA6, ARLY_CLOP1 ;  Q8XMJ8, ARLY_CLOPE ;  A9KQ51, ARLY_CLOPH ;
DR   P59616, ARLY_CLOTE ;  A3DBU0, ARLY_CLOTH ;  Q01592, ARLY_COLLI ;
DR   Q6NHG4, ARLY_CORDI ;  Q8FTM8, ARLY_COREF ;  A4QDZ5, ARLY_CORGB ;
DR   O88101, ARLY_CORGL ;  Q4JVZ7, ARLY_CORJK ;  Q0K7M0, ARLY_CUPNH ;
DR   Q474V6, ARLY_CUPPJ ;  B1X082, ARLY_CYAA5 ;  B7K8U6, ARLY_CYAP7 ;
DR   B7K2S1, ARLY_CYAP8 ;  Q479S1, ARLY_DECAR ;  Q3Z726, ARLY_DEHE1 ;
DR   A5FQ74, ARLY_DEHSB ;  Q3ZYF9, ARLY_DEHSC ;  C1CXS0, ARLY_DEIDV ;
DR   Q1IWM5, ARLY_DEIGD ;  Q9RWJ0, ARLY_DEIRA ;  B8FH31, ARLY_DESAA ;
DR   C6BTR8, ARLY_DESAD ;  B1I1D1, ARLY_DESAP ;  B8IZS3, ARLY_DESDA ;
DR   Q30YB9, ARLY_DESDG ;  B8FWX3, ARLY_DESHD ;  Q24ZG7, ARLY_DESHY ;
DR   Q6AR60, ARLY_DESPS ;  A4J174, ARLY_DESRM ;  Q72D36, ARLY_DESVH ;
DR   B8DN65, ARLY_DESVM ;  A1VEQ1, ARLY_DESVV ;  A8LL46, ARLY_DINSH ;
DR   A7ZUH8, ARLY_ECO24 ;  B7UNT6, ARLY_ECO27 ;  B7MI96, ARLY_ECO45 ;
DR   B7LA60, ARLY_ECO55 ;  Q8X730, ARLY_ECO57 ;  B5Z062, ARLY_ECO5E ;
DR   B7NU40, ARLY_ECO7I ;  B7MR51, ARLY_ECO81 ;  B7M714, ARLY_ECO8A ;
DR   C5A0Q9, ARLY_ECOBW ;  B1XBC5, ARLY_ECODH ;  A8A768, ARLY_ECOHS ;
DR   A1AID8, ARLY_ECOK1 ;  Q0TAA0, ARLY_ECOL5 ;  Q8FB96, ARLY_ECOL6 ;
DR   B1IVB8, ARLY_ECOLC ;  P11447, ARLY_ECOLI ;  B7NFR0, ARLY_ECOLU ;
DR   B6I5H6, ARLY_ECOSE ;  Q1R3V1, ARLY_ECOUT ;  C5BC57, ARLY_EDWI9 ;
DR   Q3YSS4, ARLY_EHRCJ ;  Q2GFQ7, ARLY_EHRCR ;  Q5FH83, ARLY_EHRRG ;
DR   Q5HBZ4, ARLY_EHRRW ;  A4WG51, ARLY_ENT38 ;  A7ML84, ARLY_ENTS8 ;
DR   Q6DAQ9, ARLY_ERWCT ;  B2VGA9, ARLY_ERWT9 ;  B7LUN5, ARLY_ESCF3 ;
DR   C4Z0V2, ARLY_EUBE2 ;  B1YJ36, ARLY_EXIS2 ;  C4L2P3, ARLY_EXISA ;
DR   Q2J867, ARLY_FRASC ;  B5ED16, ARLY_GEOBB ;  Q5KW95, ARLY_GEOKA ;
DR   B3E9X6, ARLY_GEOLS ;  Q39Z69, ARLY_GEOMG ;  B9M377, ARLY_GEOSF ;
DR   Q74GT9, ARLY_GEOSL ;  C6E6Y9, ARLY_GEOSM ;  C5D678, ARLY_GEOSW ;
DR   A4IRS2, ARLY_GEOTN ;  A5GDA7, ARLY_GEOUR ;  Q7NLS0, ARLY_GLOVI ;
DR   A9HRH6, ARLY_GLUDA ;  Q5FPK5, ARLY_GLUOX ;  Q7VME5, ARLY_HAEDU ;
DR   Q4QM89, ARLY_HAEI8 ;  A5UDR3, ARLY_HAEIE ;  A5UHW3, ARLY_HAEIG ;
DR   P44314, ARLY_HAEIN ;  B8F531, ARLY_HAEPS ;  Q0I2U1, ARLY_HAES1 ;
DR   B0UTI4, ARLY_HAES2 ;  Q2SQ67, ARLY_HAHCH ;  A1WVT8, ARLY_HALHL ;
DR   Q5UZ47, ARLY_HALMA ;  B0R7V5, ARLY_HALS3 ;  Q9HMQ3, ARLY_HALSA ;
DR   Q7VFF8, ARLY_HELHP ;  Q8GDU5, ARLY_HELMO ;  A9AWL1, ARLY_HERA2 ;
DR   A4G3U8, ARLY_HERAR ;  P04424, ARLY_HUMAN ;  B4U6T9, ARLY_HYDS0 ;
DR   Q0BWK6, ARLY_HYPNA ;  A6SX31, ARLY_JANMA ;  Q28V48, ARLY_JANSC ;
DR   A6WCT0, ARLY_KINRD ;  B5XZ16, ARLY_KLEP3 ;  A6TGE4, ARLY_KLEP7 ;
DR   Q033U6, ARLY_LACC3 ;  B2GE78, ARLY_LACF3 ;  Q9CJ76, ARLY_LACLA ;
DR   A2RHL0, ARLY_LACLM ;  Q032X5, ARLY_LACLS ;  P59617, ARLY_LACPL ;
DR   A5VJH2, ARLY_LACRD ;  B2G6Y7, ARLY_LACRJ ;  Q1WV66, ARLY_LACS1 ;
DR   C1D665, ARLY_LARHH ;  Q1MQL6, ARLY_LAWIP ;  Q5X7P8, ARLY_LEGPA ;
DR   A5IHA2, ARLY_LEGPC ;  Q5ZY77, ARLY_LEGPH ;  Q5WZ49, ARLY_LEGPL ;
DR   Q6AGC8, ARLY_LEIXX ;  B0SHK4, ARLY_LEPBA ;  Q04RM0, ARLY_LEPBJ ;
DR   Q052A1, ARLY_LEPBL ;  B0SR12, ARLY_LEPBP ;  B1Y070, ARLY_LEPCP ;
DR   Q72RA8, ARLY_LEPIC ;  Q8F4G5, ARLY_LEPIN ;  B1MZP3, ARLY_LEUCK ;
DR   Q03W71, ARLY_LEUMM ;  Q929S8, ARLY_LISIN ;  C1KX44, ARLY_LISMC ;
DR   Q71XS3, ARLY_LISMF ;  B8DH27, ARLY_LISMH ;  Q8Y5H1, ARLY_LISMO ;
DR   A0AKJ8, ARLY_LISW6 ;  B9EAN2, ARLY_MACCJ ;  Q60HH3, ARLY_MACFA ;
DR   Q2VYN2, ARLY_MAGSA ;  A0LE33, ARLY_MAGSM ;  Q65W16, ARLY_MANSM ;
DR   Q0AM30, ARLY_MARMM ;  Q11DW5, ARLY_MESSB ;  A6UW73, ARLY_META3 ;
DR   Q8TR65, ARLY_METAC ;  Q46GJ5, ARLY_METBF ;  Q12X66, ARLY_METBU ;
DR   B7KW75, ARLY_METC4 ;  Q609I6, ARLY_METCA ;  A9W714, ARLY_METEP ;
DR   Q1GXA9, ARLY_METFK ;  Q2FR16, ARLY_METHJ ;  Q58201, ARLY_METJA ;
DR   Q8TXN9, ARLY_METKA ;  A2SQZ4, ARLY_METLZ ;  A4G0I4, ARLY_METM5 ;
DR   A9A8S8, ARLY_METM6 ;  A6VI01, ARLY_METM7 ;  Q8PUM6, ARLY_METMA ;
DR   A3CTT5, ARLY_METMJ ;  O74026, ARLY_METMP ;  B8ILR2, ARLY_METNO ;
DR   B1ZKR9, ARLY_METPB ;  B8GH19, ARLY_METPE ;  A2SET3, ARLY_METPP ;
DR   B1M509, ARLY_METRJ ;  B0UJ26, ARLY_METS4 ;  B8EPF2, ARLY_METSB ;
DR   Q2NGN7, ARLY_METST ;  O26369, ARLY_METTH ;  A0B6F9, ARLY_METTP ;
DR   A6URI4, ARLY_METVS ;  B0JXI2, ARLY_MICAN ;  Q2RG68, ARLY_MOOTA ;
DR   Q91YI0, ARLY_MOUSE ;  A0QHA7, ARLY_MYCA1 ;  B1MB03, ARLY_MYCA9 ;
DR   P0A4Z1, ARLY_MYCBO ;  A1KJ76, ARLY_MYCBP ;  C1ANT2, ARLY_MYCBT ;
DR   A4T9W3, ARLY_MYCGI ;  B8ZRK9, ARLY_MYCLB ;  Q9CC09, ARLY_MYCLE ;
DR   B2HR33, ARLY_MYCMM ;  Q740I3, ARLY_MYCPA ;  A0QYS5, ARLY_MYCS2 ;
DR   A3Q0T2, ARLY_MYCSJ ;  A1UH95, ARLY_MYCSK ;  Q1B7R2, ARLY_MYCSS ;
DR   A5U316, ARLY_MYCTA ;  P0A4Z0, ARLY_MYCTU ;  A0PP80, ARLY_MYCUA ;
DR   A1TAA5, ARLY_MYCVP ;  Q3IME1, ARLY_NATPD ;  B2A8E3, ARLY_NATTJ ;
DR   Q5FA15, ARLY_NEIG1 ;  A9M2R4, ARLY_NEIM0 ;  Q9JVG7, ARLY_NEIMA ;
DR   Q9K0G8, ARLY_NEIMB ;  A1KSP4, ARLY_NEIMF ;  Q0AGL1, ARLY_NITEC ;
DR   Q82TN0, ARLY_NITEU ;  Q1QHU1, ARLY_NITHX ;  A9A331, ARLY_NITMS ;
DR   Q2Y6K2, ARLY_NITMU ;  Q3JDS2, ARLY_NITOC ;  A6Q2R2, ARLY_NITSB ;
DR   Q3SUR0, ARLY_NITWN ;  Q5YYD2, ARLY_NOCFA ;  A1SJJ4, ARLY_NOCSJ ;
DR   Q9LAE5, ARLY_NOSP7 ;  Q8YQE6, ARLY_NOSS1 ;  Q2G4W0, ARLY_NOVAD ;
DR   Q8ELT9, ARLY_OCEIH ;  A6WXL6, ARLY_OCHA4 ;  A6LI67, ARLY_PARD8 ;
DR   A1B3M0, ARLY_PARDP ;  A7HTI8, ARLY_PARL1 ;  P57909, ARLY_PASMU ;
DR   C6DI79, ARLY_PECCP ;  Q3A1V0, ARLY_PELCD ;  Q3B426, ARLY_PELLD ;
DR   B4S9T4, ARLY_PELPB ;  A1ATU1, ARLY_PELPD ;  A5D4Y2, ARLY_PELTS ;
DR   Q4FNK3, ARLY_PELUB ;  A9BIA3, ARLY_PETMO ;  Q7MYD9, ARLY_PHOLL ;
DR   A1VRW9, ARLY_POLNA ;  B1XVG9, ARLY_POLNS ;  A4SWK9, ARLY_POLSQ ;
DR   B4S7P9, ARLY_PROA2 ;  Q6A816, ARLY_PROAC ;  A3PA59, ARLY_PROM0 ;
DR   A2BZB5, ARLY_PROM1 ;  A8G1Z9, ARLY_PROM2 ;  A2C5K9, ARLY_PROM3 ;
DR   A9B9L0, ARLY_PROM4 ;  A2BTV0, ARLY_PROM5 ;  Q31DH2, ARLY_PROM9 ;
DR   Q7VEK0, ARLY_PROMA ;  B4F1G9, ARLY_PROMH ;  Q7TV86, ARLY_PROMM ;
DR   Q7TUI1, ARLY_PROMP ;  A2BND8, ARLY_PROMS ;  Q46I50, ARLY_PROMT ;
DR   Q48QD3, ARLY_PSE14 ;  Q15X84, ARLY_PSEA6 ;  A6VE40, ARLY_PSEA7 ;
DR   B7V5F3, ARLY_PSEA8 ;  Q02EA0, ARLY_PSEAB ;  P50987, ARLY_PSEAE ;
DR   Q1I314, ARLY_PSEE4 ;  Q4K3X1, ARLY_PSEF5 ;  C3K426, ARLY_PSEFS ;
DR   A4XNY5, ARLY_PSEMY ;  B0KH03, ARLY_PSEPG ;  P59618, ARLY_PSEPK ;
DR   B1J1V0, ARLY_PSEPW ;  Q88B94, ARLY_PSESM ;  Q500N3, ARLY_PSEU2 ;
DR   A4VGX6, ARLY_PSEU5 ;  Q4FVJ6, ARLY_PSYA2 ;  Q1QEM4, ARLY_PSYCK ;
DR   Q8ZU95, ARLY_PYRAE ;  A4WJI4, ARLY_PYRAR ;  A3MT36, ARLY_PYRCJ ;
DR   Q8U483, ARLY_PYRFU ;  A1RR78, ARLY_PYRIL ;  Q1LJQ2, ARLY_RALME ;
DR   B2UA10, ARLY_RALPJ ;  Q8XWV7, ARLY_RALSO ;  P51464, ARLY_RANCA ;
DR   P20673, ARLY_RAT   ;  A9WQ91, ARLY_RENSM ;  B3PPC1, ARLY_RHIE6 ;
DR   Q2K3P2, ARLY_RHIEC ;  Q1MB73, ARLY_RHIL3 ;  C3MHU1, ARLY_RHISN ;
DR   Q7UK64, ARLY_RHOBA ;  Q93JQ9, ARLY_RHOFA ;  Q21XR4, ARLY_RHOFD ;
DR   C1ASZ5, ARLY_RHOOB ;  Q2J1X2, ARLY_RHOP2 ;  Q6N0L9, ARLY_RHOPA ;
DR   Q20WT9, ARLY_RHOPB ;  Q13CL5, ARLY_RHOPS ;  B3QCB2, ARLY_RHOPT ;
DR   Q2RXE3, ARLY_RHORT ;  A3PMB7, ARLY_RHOS1 ;  Q3IZY2, ARLY_RHOS4 ;
DR   A4WVB9, ARLY_RHOS5 ;  Q0SI59, ARLY_RHOSR ;  A7NF38, ARLY_ROSCS ;
DR   Q169X5, ARLY_ROSDO ;  A5UVX7, ARLY_ROSS1 ;  A1AX52, ARLY_RUTMC ;
DR   Q21EF4, ARLY_SACD2 ;  P41906, ARLY_SACDO ;  A4FKC1, ARLY_SACEN ;
DR   B5F0U9, ARLY_SALA4 ;  A9MHH3, ARLY_SALAR ;  Q57H93, ARLY_SALCH ;
DR   B5FPX5, ARLY_SALDC ;  B5QXQ5, ARLY_SALEP ;  B5RF45, ARLY_SALG2 ;
DR   B4TCQ6, ARLY_SALHS ;  B4T0X1, ARLY_SALNS ;  Q5PK73, ARLY_SALPA ;
DR   A9N0H0, ARLY_SALPB ;  C0Q476, ARLY_SALPC ;  B5BJN4, ARLY_SALPK ;
DR   B4TQH6, ARLY_SALSV ;  Q8Z311, ARLY_SALTI ;  Q8ZKL6, ARLY_SALTY ;
DR   P40369, ARLY_SCHPO ;  A8GL81, ARLY_SERP5 ;  A1S265, ARLY_SHEAM ;
DR   B8EBF9, ARLY_SHEB2 ;  A3DA22, ARLY_SHEB5 ;  A6WTR9, ARLY_SHEB8 ;
DR   A9KTY6, ARLY_SHEB9 ;  Q12SM6, ARLY_SHEDO ;  B0TL84, ARLY_SHEHH ;
DR   A3Q9D0, ARLY_SHELP ;  Q8EK27, ARLY_SHEON ;  A8GZ22, ARLY_SHEPA ;
DR   A4YBT8, ARLY_SHEPC ;  B8CNI1, ARLY_SHEPW ;  A0L250, ARLY_SHESA ;
DR   A8G1A3, ARLY_SHESH ;  Q0HDU9, ARLY_SHESM ;  Q0I060, ARLY_SHESR ;
DR   A1RPR5, ARLY_SHESW ;  B1KP64, ARLY_SHEWM ;  B2TWF5, ARLY_SHIB3 ;
DR   Q31U28, ARLY_SHIBS ;  Q32AB5, ARLY_SHIDS ;  Q0SY34, ARLY_SHIF8 ;
DR   P59619, ARLY_SHIFL ;  Q3YV16, ARLY_SHISS ;  Q5LXC0, ARLY_SILPO ;
DR   Q2NQZ1, ARLY_SODGM ;  Q024T3, ARLY_SOLUE ;  A9FJ48, ARLY_SORC5 ;
DR   Q1GWP7, ARLY_SPHAL ;  A5VAA0, ARLY_SPHWW ;  A7X0H4, ARLY_STAA1 ;
DR   A6U067, ARLY_STAA2 ;  Q2FIB5, ARLY_STAA3 ;  Q2FZU2, ARLY_STAA8 ;
DR   A5IRD8, ARLY_STAA9 ;  Q2YWS5, ARLY_STAAB ;  Q5HHC5, ARLY_STAAC ;
DR   A6QFH1, ARLY_STAAE ;  P63582, ARLY_STAAM ;  P63583, ARLY_STAAN ;
DR   Q6GIC8, ARLY_STAAR ;  Q6GAW6, ARLY_STAAS ;  A8Z066, ARLY_STAAT ;
DR   Q8NXF3, ARLY_STAAW ;  B9DIU3, ARLY_STACT ;  Q5HQK1, ARLY_STAEQ ;
DR   Q8CT81, ARLY_STAES ;  Q4L4X6, ARLY_STAHJ ;  Q49W99, ARLY_STAS1 ;
DR   Q3K3Q3, ARLY_STRA1 ;  Q8E7N0, ARLY_STRA3 ;  Q8E271, ARLY_STRA5 ;
DR   Q827Z0, ARLY_STRAW ;  P50988, ARLY_STRCL ;  Q9L1B1, ARLY_STRCO ;
DR   A8AUN7, ARLY_STRGC ;  B1W3B4, ARLY_STRGG ;  B4SQ92, ARLY_STRM5 ;
DR   B2FMD6, ARLY_STRMK ;  Q8DVX5, ARLY_STRMU ;  Q04MW6, ARLY_STRP2 ;
DR   C1CAC7, ARLY_STRP7 ;  B1I815, ARLY_STRPI ;  Q8DRI4, ARLY_STRR6 ;
DR   A4W487, ARLY_STRS2 ;  A3CQQ3, ARLY_STRSV ;  A4VXZ3, ARLY_STRSY ;
DR   Q5LXZ9, ARLY_STRT1 ;  Q5M2K3, ARLY_STRT2 ;  Q03IP9, ARLY_STRTD ;
DR   B9DVV8, ARLY_STRU0 ;  C1CBS9, ARLY_STRZJ ;  Q4J8F0, ARLY_SULAC ;
DR   Q30S87, ARLY_SULDN ;  A6Q7P5, ARLY_SULNB ;  Q9UX32, ARLY_SULSO ;
DR   B2V6Y7, ARLY_SULSY ;  Q970U9, ARLY_SULTO ;  Q67S72, ARLY_SYMTH ;
DR   Q2LT96, ARLY_SYNAS ;  Q8GIS1, ARLY_SYNE7 ;  A0LEB1, ARLY_SYNFM ;
DR   Q2JXY9, ARLY_SYNJA ;  Q2JJY4, ARLY_SYNJB ;  Q5N1K1, ARLY_SYNP6 ;
DR   A5GHM4, ARLY_SYNPW ;  Q7TTY1, ARLY_SYNPX ;  Q0IE70, ARLY_SYNS3 ;
DR   Q3B0Z0, ARLY_SYNS9 ;  Q3ANN7, ARLY_SYNSC ;  P73257, ARLY_SYNY3 ;
DR   Q8DLW0, ARLY_THEEB ;  Q47N85, ARLY_THEFY ;  Q9Z4S3, ARLY_THENN ;
DR   B1YB49, ARLY_THENV ;  B0KBW6, ARLY_THEP3 ;  B0K4D9, ARLY_THEPX ;
DR   Q72GZ4, ARLY_THET2 ;  Q5SLL0, ARLY_THET8 ;  Q8R7C3, ARLY_THETN ;
DR   Q31JG7, ARLY_THICR ;  Q3SM68, ARLY_THIDA ;  B8GSV2, ARLY_THISH ;
DR   C4L7S8, ARLY_TOLAT ;  Q8KTQ9, ARLY_TREPR ;  Q0W7A4, ARLY_UNCMA ;
DR   C5CRT0, ARLY_VARPS ;  A5F4Z3, ARLY_VIBC3 ;  Q9KNT9, ARLY_VIBCH ;
DR   C3LRV2, ARLY_VIBCM ;  Q5E2E8, ARLY_VIBF1 ;  P59620, ARLY_VIBPA ;
DR   Q8DCM9, ARLY_VIBVU ;  Q7MH73, ARLY_VIBVY ;  Q7M938, ARLY_WOLSU ;
DR   Q8PK32, ARLY_XANAC ;  Q3BSI8, ARLY_XANC5 ;  Q4UVI4, ARLY_XANC8 ;
DR   B0RS55, ARLY_XANCB ;  Q8P8J9, ARLY_XANCP ;  Q2P2F7, ARLY_XANOM ;
DR   B2SHW2, ARLY_XANOP ;  A7IG40, ARLY_XANP2 ;  Q9PEM5, ARLY_XYLFA ;
DR   P59621, ARLY_XYLFT ;  P04076, ARLY_YEAST ;  A1JI24, ARLY_YERE8 ;
DR   A7FD01, ARLY_YERP3 ;  Q1CBV4, ARLY_YERPA ;  B2JZE4, ARLY_YERPB ;
DR   Q8ZA88, ARLY_YERPE ;  A9R514, ARLY_YERPG ;  Q1CNQ3, ARLY_YERPN ;
DR   A4TRH3, ARLY_YERPP ;  Q66G70, ARLY_YERPS ;  B1JQ59, ARLY_YERPY ;
DR   Q9Z660, ARLY_ZYMMO ;  P50514, ARLZ_SCHPO ;
//
ID   4.3.2.2
DE   Adenylosuccinate lyase.
AN   Adenylosuccinase.
AN   Succino AMP-lyase.
CA   (1) N(6)-(1,2-dicarboxyethyl)AMP = fumarate + AMP.
CA   (2) (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-
CA   carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-
CA   ribosyl)imidazole-4-carboxamide.
CC   -!- Also acts on 1-(5-phosphoribosyl)-4-(N-succinocarboxamide)-5-
CC       aminoimidazole.
PR   PROSITE; PDOC00147;
DR   O66856, PUR8_AQUAE ;  O28041, PUR8_ARCFU ;  P12047, PUR8_BACSU ;
DR   A3KN12, PUR8_BOVIN ;  P57351, PUR8_BUCAI ;  Q8K9Q7, PUR8_BUCAP ;
DR   Q89AM3, PUR8_BUCBP ;  Q60Q90, PUR8_CAEBR ;  Q21774, PUR8_CAEEL ;
DR   P21265, PUR8_CHICK ;  Q9RSE6, PUR8_DEIRA ;  Q54J34, PUR8_DICDI ;
DR   P0AB90, PUR8_ECOL6 ;  P0AB89, PUR8_ECOLI ;  P44797, PUR8_HAEIN ;
DR   Q9ZKA2, PUR8_HELPJ ;  P56468, PUR8_HELPY ;  P30566, PUR8_HUMAN ;
DR   A5IGB3, PUR8_LEGPC ;  Q5ZXD1, PUR8_LEGPH ;  Q8HXY5, PUR8_MACFA ;
DR   Q58339, PUR8_METJA ;  O27580, PUR8_METTH ;  P54822, PUR8_MOUSE ;
DR   Q9I0K9, PUR8_PSEAE ;  Q9UZ99, PUR8_PYRAB ;  O58582, PUR8_PYRHO ;
DR   O60105, PUR8_SCHPO ;  P52201, PUR8_SPICI ;  Q2FFI7, PUR8_STAA3 ;
DR   Q2G2S0, PUR8_STAA8 ;  Q2YU66, PUR8_STAAB ;  Q5HEL4, PUR8_STAAC ;
DR   Q99SX9, PUR8_STAAM ;  Q7A4Q3, PUR8_STAAN ;  Q6GFE9, PUR8_STAAR ;
DR   Q6G825, PUR8_STAAS ;  Q7A0G9, PUR8_STAAW ;  Q5HN26, PUR8_STAEQ ;
DR   Q8CRT6, PUR8_STAES ;  Q4L7M3, PUR8_STAHJ ;  Q49YV3, PUR8_STAS1 ;
DR   P72478, PUR8_STRMU ;  P74384, PUR8_SYNY3 ;  Q9X0I0, PUR8_THEMA ;
DR   Q05911, PUR8_YEAST ;
//
ID   4.3.2.3
DE   Ureidoglycolate lyase.
AN   Ureidoglycolase.
AN   Ureidoglycolatase.
AN   Ureidoglycolate hydrolase.
CA   (S)-ureidoglycolate = glyoxylate + urea.
DR   B1Z1Y2, UGL_BURA4  ;  Q1BJJ1, UGL_BURCA  ;  B1K3Y3, UGL_BURCC  ;
DR   A0B3M8, UGL_BURCH  ;  B4EKX6, UGL_BURCJ  ;  Q0B628, UGL_BURCM  ;
DR   A9ALD1, UGL_BURM1  ;  Q39BA7, UGL_BURS3  ;
//
ID   4.3.2.4
DE   Purine imidazole-ring cyclase.
CA   DNA 4,6-diamino-5-formamidopyrimidine = DNA adenine + H(2)O.
CC   -!- Also acts on 2,6-diamino-5-formamido-3,4-dihydro-4-oxopyrimidine
CC       residues.
CC   -!- Brings about the reclosure of the imidazole rings of purine residues
CC       damaged by gamma-rays.
//
ID   4.3.2.5
DE   Peptidylamidoglycolate lyase.
AN   Alpha-hydroxyglycine amidating dealkylase.
CA   Peptidylamidoglycolate = peptidyl amide + glyoxylate.
CC   -!- Acts on the product of the reaction catalyzed by EC 1.14.17.3, thus
CC       removing a terminal glycine residue and leaving a des-glycine peptide
CC       amide.
DR   P08478, AMDA_XENLA ;  P12890, AMDB_XENLA ;  P83388, AMDL_CAEEL ;
DR   P10731, AMD_BOVIN  ;  P19021, AMD_HUMAN  ;  P97467, AMD_MOUSE  ;
DR   P14925, AMD_RAT    ;  Q9V5E1, PAL1_DROME ;  Q9W1L5, PAL2_DROME ;
DR   P91268, PAL_CAEEL  ;
//
ID   4.3.3.1
DE   3-ketovalidoxylamine C-N-lyase.
CA   4-nitrophenyl-3-ketovalidamine = 4-nitroaniline + 5-D-(5/6)-5-
CA   C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one.
CF   Calcium.
CC   -!- Eliminates 4-nitroaniline from 4-nitrophenyl-3-ketovalidamine or
CC       4-nitrophenol from 4-nitrophenyl-alpha-D-3-dehydroglucoside.
CC   -!- Involved in the degradation of the fungicide validamycin A by
CC       Flavobacterium saccharophilum.
//
ID   4.3.3.2
DE   Strictosidine synthase.
AN   STR.
AN   Strictosidine synthetase.
CA   3-alpha-(S)-strictosidine + H(2)O = tryptamine + secologanin.
CC   -!- Catalyzes a a Pictet-Spengler reaction between the aldehyde group of
CC       secologanin and the amino group of tryptamine.
CC   -!- Involved in the biosynthesis of the monoterpenoid indole alkaloids.
DR   P94111, STS1_ARATH ;  P92976, STS3_ARATH ;  P18417, STSY_CATRO ;
DR   P68174, STSY_RAUMA ;  P68175, STSY_RAUSE ;
//
ID   4.3.3.3
DE   Deacetylisoipecoside synthase.
CA   Deacetylisoipecoside + H(2)O = dopamine + secologanin.
CC   -!- The enzyme from the leaves of Alangium lamarckii differs in
CC       enantiomeric specificity from EC 4.3.3.4.
CC   -!- The product is rapidly converted to demethylisoalangiside.
//
ID   4.3.3.4
DE   Deacetylipecoside synthase.
CA   Deacetylipecoside + H(2)O = dopamine + secologanin.
CC   -!- The enzyme from the leaves of Alangium lamarckii differs in
CC       enantiomeric specificity from EC 4.3.3.3.
CC   -!- The product is rapidly converted to demethylalangiside.
//
ID   4.3.3.5
DE   4'-demethylrebeccamycin synthase.
AN   Arcyriaflavin A N-glycosyltransferase.
CA   4'-O-demethylrebeccamycin + H(2)O = dichloro-arcyriaflavin A + beta-D-
CA   glucose.
CC   -!- This enzyme catalyzes a step in the biosynthesis of rebeccamycin,
CC       an indolocarbazole alkaloid produced by the actinobacterium
CC       Lechevalieria aerocolonigenes.
CC   -!- The enzyme is a glycosylase, and acts in the reverse direction to
CC       that shown.
CC   -!- It has a wide substrate range, and was shown to glycosylate several
CC       substrates, including the staurosporine aglycone, EJG-III-108A,
CC       J-104303, 6-N-methyl-arcyriaflavin C and indolo-[2,3-a]-carbazole.
//
ID   4.3.99.1
DE   Transferred entry: 4.2.1.104.
//
ID   4.3.99.2
DE   Carboxybiotin decarboxylase.
AN   Carboxybiotin protein decarboxylase.
CA   A carboxybiotinyl-[protein] + 1-2 Na(+)(In) + H(+)(Out) = CO(2) +
CA   a biotinyl-[protein] + 1-2 Na(+)(Out).
CC   -!- The integral membrane protein MadB from the anaerobic bacterium
CC       Malonomonas rubra is a component of the multienzyme complex
CC       EC 4.1.1.89.
CC   -!- The free energy of the decarboxylation reaction is used to pump Na(+)
CC       out of the cell.
//
ID   4.4.1.1
DE   Cystathionine gamma-lyase.
AN   Cystathionase.
AN   Cystathioninase.
AN   Cysteine desulfhydrase.
AN   Cystine desulfhydrase.
AN   Gamma-cystathionase.
AN   Homoserine deaminase.
AN   Homoserine dehydratase.
CA   L-cystathionine + H(2)O = L-cysteine + NH(3) + 2-oxobutanoate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Also catalyzes elimination reactions of L-homoserine to form H(2)O,
CC       NH(3) and 2-oxobutanoate, of L-cystine, producing thiocysteine,
CC       pyruvate and NH(3), and of L-cysteine producing pyruvate, NH(3) and
CC       H(2)S.
CC   -!- Formerly EC 4.2.1.15.
PR   PROSITE; PDOC00677;
DR   P55216, CGL2_CAEEL ;  Q58DW2, CGL_BOVIN  ;  Q55DV9, CGL_DICDI  ;
DR   P32929, CGL_HUMAN  ;  Q60HG7, CGL_MACFA  ;  Q8VCN5, CGL_MOUSE  ;
DR   Q19QT7, CGL_PIG    ;  P18757, CGL_RAT    ;  P31373, CYS3_YEAST ;
DR   Q59829, CYSA_STRCO ;  O05394, MCCB_BACSU ;
//
ID   4.4.1.2
DE   Homocysteine desulfhydrase.
AN   Homocysteine desulfurase.
CA   L-homocysteine + H(2)O = H(2)S + NH(3) + 2-oxobutanoate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Formerly EC 1.2.1.1.
DR   O05394, MCCB_BACSU ;
//
ID   4.4.1.3
DE   Dimethylpropiothetin dethiomethylase.
CA   S,S-dimethyl-beta-propiothetin = dimethyl sulfide + acrylate.
//
ID   4.4.1.4
DE   Alliin lyase.
AN   Alliinase.
AN   Cysteine sulfoxide lyase.
AN   Cysteine sulphoxide lyase.
AN   L-cysteine sulfoxide lyase.
CA   An S-alkyl-L-cysteine S-oxide = an alkyl sulfenate + 2-aminoacrylate.
CF   Pyridoxal 5'-phosphate.
DR   Q01594, ALLN1_ALLSA;  Q41233, ALLN2_ALLSA;  P31757, ALLN_ALLCE ;
DR   P31756, ALLN_ALLCG ;
//
ID   4.4.1.5
DE   Lactoylglutathione lyase.
AN   (R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing).
AN   Aldoketomutase.
AN   Glyoxalase I.
AN   Ketone-aldehyde mutase.
AN   Methylglyoxalase.
CA   (R)-S-lactoylglutathione = glutathione + methylglyoxal.
CC   -!- Also acts on 3-phosphoglycerol-glutathione.
PR   PROSITE; PDOC00720;
DR   Q8W593, LGUC_ARATH ;  Q8H0V3, LGUL_ARATH ;  O04885, LGUL_BRAJU ;
DR   Q39366, LGUL_BRAOG ;  O49818, LGUL_CICAR ;  P0AC82, LGUL_ECO57 ;
DR   P0AC81, LGUL_ECOLI ;  P44638, LGUL_HAEIN ;  Q04760, LGUL_HUMAN ;
DR   Q4R5F2, LGUL_MACFA ;  Q9CPU0, LGUL_MOUSE ;  P0A0T2, LGUL_NEIMA ;
DR   P0A0T3, LGUL_NEIMB ;  Q948T6, LGUL_ORYSJ ;  P84719, LGUL_PINST ;
DR   Q9HU72, LGUL_PSEAE ;  P16635, LGUL_PSEPU ;  Q6P7Q4, LGUL_RAT   ;
DR   P0A1Q3, LGUL_SALTI ;  P0A1Q2, LGUL_SALTY ;  Q09751, LGUL_SCHPO ;
DR   P0AC83, LGUL_SHIFL ;  Q42891, LGUL_SOLLC ;  Q9ZS21, LGUL_SOYBN ;
DR   Q55595, LGUL_SYNY3 ;  Q9KT93, LGUL_VIBCH ;  P46235, LGUL_VIBPA ;
DR   P50107, LGUL_YEAST ;
//
ID   4.4.1.6
DE   S-alkylcysteine lyase.
AN   S-alkyl-L-cysteinase.
AN   S-alkyl-L-cysteine alkylthiol-lyase (deaminating).
AN   S-alkyl-L-cysteine lyase.
AN   S-alkyl-L-cysteine sulfoxide lyase.
CA   An S-alkyl-L-cysteine + H(2)O = an alkyl thiol + NH(3) + pyruvate.
CF   Pyridoxal 5'-phosphate.
CC   -!- Decomposes S-alkyl-L-cysteines by alpha,beta-elimination.
CC   -!- Possibly identical, in Saccharomyces cerevisiae, with EC 4.4.1.8.
//
ID   4.4.1.7
DE   Transferred entry: 2.5.1.18.
//
ID   4.4.1.8
DE   Cystathionine beta-lyase.
AN   Beta C-S lyase.
AN   Beta-cystathionase.
AN   Cysteine lyase.
AN   Cystine lyase.
CA   L-cystathionine + H(2)O = L-homocysteine + NH(3) + pyruvate.
CF   Pyridoxal 5'-phosphate.
CC   -!- The enzyme from some sources also acts on L-cystine, forming
CC       pyruvate, ammonia and cysteine persulfide, and a number of related
CC       compounds.
CC   -!- Possibly identical, in Saccharomyces cerevisiae, with EC 4.4.1.6.
PR   PROSITE; PDOC00518;
PR   PROSITE; PDOC00677;
DR   Q08432, CBL_BACSU  ;  P63503, CBL_MYCBO  ;  Q9CBM9, CBL_MYCLE  ;
DR   P63502, CBL_MYCTU  ;  O94350, CBL_SCHPO  ;  P23256, MALY_ECOLI ;
DR   P53780, METC_ARATH ;  O31632, METC_BACSU ;  Q07703, METC_BORAV ;
DR   Q83A83, METC_COXBU ;  P85217, METC_CRYLA ;  P06721, METC_ECOLI ;
DR   P44527, METC_HAEIN ;  P0A4K2, METC_LACLA ;  P0C2T9, METC_LACLC ;
DR   A2RM21, METC_LACLM ;  Q52811, METC_RHIL3 ;  P18949, METC_SALTY ;
DR   P43623, METC_YEAST ;  P53101, STR3_YEAST ;
//
ID   4.4.1.9
DE   L-3-cyanoalanine synthase.
AN   Beta-cyano-L-alanine synthase.
AN   Beta-cyanoalanine synthase.
CA   L-cysteine + hydrogen cyanide = L-3-cyanoalanine + hydrogen sulfide.
CF   Pyridoxal 5'-phosphate.
//
ID   4.4.1.10
DE   Cysteine lyase.
CA   L-cysteine + sulfite = L-cysteate + H(2)S.
CF   Pyridoxal 5'-phosphate.
CC   -!- Can use a second molecule of cysteine (producing lanthionine) or
CC       other alkyl thiols as replacing agents.
//
ID   4.4.1.11
DE   Methionine gamma-lyase.
AN   L-methioninase.
AN   Methionine lyase.
CA   L-methionine + H(2)O = methanethiol + NH(3) + 2-oxobutanoate.
CF   Pyridoxal 5'-phosphate.
PR   PROSITE; PDOC00677;
DR   P13254, MEGL_PSEPU ;
//
ID   4.4.1.12
DE   Deleted entry.
//
ID   4.4.1.13
DE   Cysteine-S-conjugate beta-lyase.
AN   L-cysteine-S-conjugate thiol-lyase (deaminating).
CA   RS-CH(2)-CH(NH(3)(+))COO(-) = RSH + NH(3) + pyruvate.
CF   Pyridoxal 5'-phosphate.
CC   -!- R may represent aromatic compounds such as 4-bromobenzene and 2,4-
CC       dinitrobenzene.
DR   Q16773, KAT1_HUMAN ;  Q8BTY1, KAT1_MOUSE ;  Q08415, KAT1_RAT   ;
DR   Q0P5G4, KAT3_BOVIN ;  Q7T3E5, KAT3_DANRE ;  Q6YP21, KAT3_HUMAN ;
DR   Q71RI9, KAT3_MOUSE ;  Q58FK9, KAT3_RAT   ;  Q54KM6, KAT_DICDI  ;
//
ID   4.4.1.14
DE   1-aminocyclopropane-1-carboxylate synthase.
AN   1-aminocyclopropane-1-carboxylic acid synthase.
AN   ACC synthase.
AN   Aminocyclopropanecarboxylate synthase.
AN   S-adenosyl-L-methionine methylthioadenosine-lyase.
CA   S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate +
CA   methylthioadenosine.
CF   Pyridoxal 5'-phosphate.
CC   -!- Catalyzes an alpha,gamma-elimination.
PR   PROSITE; PDOC00098;
DR   Q9S9U6, 1A111_ARATH;  P23599, 1A11_CUCMA ;  P23279, 1A11_CUCPE ;
DR   A2XLL2, 1A11_ORYSI ;  Q10DK7, 1A11_ORYSJ ;  Q9MB95, 1A11_PRUMU ;
DR   Q06402, 1A12_ARATH ;  Q00257, 1A12_CUCMA ;  Q00379, 1A12_CUCPE ;
DR   P18485, 1A12_SOLLC ;  Q42881, 1A13_SOLLC ;  Q43309, 1A14_ARATH ;
DR   P29535, 1A14_SOLLC ;  Q37001, 1A15_ARATH ;  Q9SAR0, 1A16_ARATH ;
DR   Q9STR4, 1A17_ARATH ;  Q9T065, 1A18_ARATH ;  Q9M2Y8, 1A19_ARATH ;
DR   P27486, 1A1C_DIACA ;  P37821, 1A1C_MALDO ;  P31531, 1A1C_SOYBN ;
DR   Q07262, 1A1C_TOBAC ;  Q01912, 1A1C_VIGRR ;
//
ID   4.4.1.15
DE   D-cysteine desulfhydrase.
CA   D-cysteine + H(2)O = H(2)S + NH(3) + pyruvate.
DR   B7UST8, DCYD_ECO27 ;  B7MCH6, DCYD_ECO45 ;  B7L8T2, DCYD_ECO55 ;
DR   Q8XBC7, DCYD_ECO57 ;  B5YRU5, DCYD_ECO5E ;  B7NRG1, DCYD_ECO7I ;
DR   B7MWA6, DCYD_ECO81 ;  B7M363, DCYD_ECO8A ;  C4ZQJ7, DCYD_ECOBW ;
DR   B1X677, DCYD_ECODH ;  A8A1C2, DCYD_ECOHS ;  P59329, DCYD_ECOL6 ;
DR   B1IZY5, DCYD_ECOLC ;  P76316, DCYD_ECOLI ;  B7NBR4, DCYD_ECOLU ;
DR   B1LQT7, DCYD_ECOSM ;  Q1RAM1, DCYD_ECOUT ;  B7LP46, DCYD_ESCF3 ;
DR   B5XPW3, DCYD_KLEP3 ;  A6TB69, DCYD_KLEP7 ;  B5F2T4, DCYD_SALA4 ;
DR   Q57N48, DCYD_SALCH ;  B5FRX8, DCYD_SALDC ;  B5R104, DCYD_SALEP ;
DR   B5R890, DCYD_SALG2 ;  B4T849, DCYD_SALHS ;  B4SW60, DCYD_SALNS ;
DR   Q5PI07, DCYD_SALPA ;  A9MU62, DCYD_SALPB ;  C0Q2A0, DCYD_SALPC ;
DR   B5BGB4, DCYD_SALPK ;  B4TYX4, DCYD_SALSV ;  Q8Z5S9, DCYD_SALTI ;
DR   Q8ZNT7, DCYD_SALTY ;  A8GFZ8, DCYD_SERP5 ;  B2TXG4, DCYD_SHIB3 ;
DR   Q0T3K8, DCYD_SHIF8 ;  P59330, DCYD_SHIFL ;  Q3Z2U3, DCYD_SHISS ;
DR   A1JSN4, DCYD_YERE8 ;  A7FJ17, DCYD_YERP3 ;  Q8ZF73, DCYD_YERPE ;
DR   Q1CHC4, DCYD_YERPN ;  A4TK60, DCYD_YERPP ;  Q66BQ4, DCYD_YERPS ;
//
ID   4.4.1.16
DE   Selenocysteine lyase.
AN   Selenocysteine beta-lyase.
AN   Selenocysteine reductase.
CA   L-selenocysteine + reduced acceptor = selenide + L-alanine + acceptor.
CF   Pyridoxal 5'-phosphate.
CC   -!- Dithiothreitol or 2-mercaptoethanol can act as reducing agent in the
CC       reaction.
CC   -!- Does not act on cysteine, serine or chloroalanine.
DR   Q93WX6, NFS2_ARATH ;  A2VDS1, SCLY_BOVIN ;  Q96I15, SCLY_HUMAN ;
DR   Q9JLI6, SCLY_MOUSE ;  Q68FT9, SCLY_RAT   ;  Q66IQ6, SCLY_XENLA ;
DR   Q5U4Q9, SCLY_XENTR ;  A8AH80, SUFS_CITK8 ;  Q9EXP2, SUFS_DICD3 ;
DR   A7ZME5, SUFS_ECO24 ;  B7US19, SUFS_ECO27 ;  B7MA32, SUFS_ECO45 ;
DR   B7L5N2, SUFS_ECO55 ;  Q7ADI4, SUFS_ECO57 ;  B5Z4B3, SUFS_ECO5E ;
DR   B7NTV6, SUFS_ECO7I ;  B7MV59, SUFS_ECO81 ;  B7M0N5, SUFS_ECO8A ;
DR   C4ZYE2, SUFS_ECOBW ;  B1XFY8, SUFS_ECODH ;  A8A0M6, SUFS_ECOHS ;
DR   A1ABL8, SUFS_ECOK1 ;  Q0THE9, SUFS_ECOL5 ;  Q8FH54, SUFS_ECOL6 ;
DR   B1IQ76, SUFS_ECOLC ;  P77444, SUFS_ECOLI ;  B7N516, SUFS_ECOLU ;
DR   B6IBB9, SUFS_ECOSE ;  B1LE56, SUFS_ECOSM ;  Q1RBB6, SUFS_ECOUT ;
DR   A4W9R3, SUFS_ENT38 ;  A7MF59, SUFS_ENTS8 ;  Q6D625, SUFS_ERWCT ;
DR   B7LQ96, SUFS_ESCF3 ;  B5XQH2, SUFS_KLEP3 ;  A6TAE4, SUFS_KLEP7 ;
DR   C6DKM6, SUFS_PECCP ;  Q7N3U5, SUFS_PHOLL ;  B5F7C4, SUFS_SALA4 ;
DR   A9MEP3, SUFS_SALAR ;  Q57PR2, SUFS_SALCH ;  B5FIM3, SUFS_SALDC ;
DR   B5QVS9, SUFS_SALEP ;  B5RAT4, SUFS_SALG2 ;  B4TGK9, SUFS_SALHS ;
DR   B4T4R6, SUFS_SALNS ;  A9N142, SUFS_SALPB ;  B4TUT5, SUFS_SALSV ;
DR   Q8XF77, SUFS_SALTI ;  Q7CQN5, SUFS_SALTY ;  A8GDU4, SUFS_SERP5 ;
DR   B2U2I4, SUFS_SHIB3 ;  Q321D9, SUFS_SHIBS ;  Q7UAH4, SUFS_SHIFL ;
DR   Q3Z233, SUFS_SHISS ;  Q8D2J7, SUFS_WIGBR ;  A7FHJ2, SUFS_YERP3 ;
DR   Q1C761, SUFS_YERPA ;  B2K5J4, SUFS_YERPB ;  Q8D0M6, SUFS_YERPE ;
DR   A9QZC9, SUFS_YERPG ;  Q1CIJ6, SUFS_YERPN ;  A4TIP2, SUFS_YERPP ;
DR   Q66A22, SUFS_YERPS ;  B1JJ48, SUFS_YERPY ;
//
ID   4.4.1.17
DE   Holocytochrome-c synthase.
AN   Cytochrome c heme-lyase.
AN   Cytochrome c synthase.
CA   Holocytochrome c = apocytochrome c + heme.
CC   -!- In the reverse direction, the enzyme catalyzes the attachment of heme
CC       to two cysteine residues in the protein, forming thioether links.
PR   PROSITE; PDOC00647;
DR   A5PJG7, CCHL_BOVIN ;  P53703, CCHL_CAEEL ;  P53700, CCHL_CANAL ;
DR   Q5F339, CCHL_CHICK ;  Q552W5, CCHL_DICDI ;  P53701, CCHL_HUMAN ;
DR   P53702, CCHL_MOUSE ;  P14187, CCHL_NEUCR ;  O74794, CCHL_SCHPO ;
DR   P06182, CCHL_YEAST ;
//
ID   4.4.1.18
DE   Transferred entry: 1.8.3.5.
//
ID   4.4.1.19
DE   Phosphosulfolactate synthase.
AN   (2R)-phospho-3-sulfolactate synthase.
AN   PSL synthase.
CA   (2R)-2-O-phospho-3-sulfolactate = phosphoenolpyruvate + hydrogen sulfite.
CF   Magnesium.
CC   -!- The enzyme from Methanococcus jannaschii catalyzes the Michael
CC       addition of sulfite to phosphoenolpyruvate.
CC   -!- It specifically requires phosphoenolpyruvate and its broad alkaline
CC       pH optimum suggests that it uses sulfite rather than bisulfite.
DR   O06739, PSLS_BACSU ;  Q57703, PSLS_METJA ;  O27710, PSLS_METTH ;
DR   Q9AF21, PSLS_XANP2 ;
//
ID   4.4.1.20
DE   Leukotriene-C(4) synthase.
AN   Leukotriene A(4):glutathione S-leukotrienyltransferase.
AN   Leukotriene C(4) synthetase.
AN   LTC(4) synthase.
AN   LTC(4) synthetase.
CA   Leukotriene C(4) = leukotriene A(4) + glutathione.
CC   -!- The reaction proceeds in the direction of addition.
CC   -!- Not identical with EC 2.5.1.18.
CC   -!- Formerly EC 2.5.1.37.
PR   PROSITE; PDOC00999;
DR   Q2NKS0, LTC4S_BOVIN;  A6XA80, LTC4S_CAVPO;  Q16873, LTC4S_HUMAN;
DR   Q60860, LTC4S_MOUSE;  Q925U2, LTC4S_RAT  ;
//
ID   4.4.1.21
DE   S-ribosylhomocysteine lyase.
AN   S-ribosylhomocysteinase.
CA   S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = L-homocysteine + (4S)-4,5-
CA   dihydroxypentan-2,3-dione.
CF   Fe(2+).
CC   -!- The 4,5-dihydroxypentan-2,3-dione formed spontaneously cyclizes and
CC       combines with borate to form an autoinducer (AI-2) in the bacterial
CC       quorum-sensing mechanism, which is used by many bacteria to control
CC       gene expression in response to cell density.
CC   -!- Formerly EC 3.2.1.148 and EC 3.3.1.3.
DR   Q04CP9, LUXS1_LACDB;  Q049W0, LUXS2_LACDB;  A3N1L8, LUXS_ACTP2 ;
DR   B3H1Y9, LUXS_ACTP7 ;  B0BQF0, LUXS_ACTPJ ;  A6VM61, LUXS_ACTSZ ;
DR   A0KG57, LUXS_AERHH ;  A4SIY8, LUXS_AERS4 ;  B6EGB5, LUXS_ALISL ;
DR   A8ER22, LUXS_ARCB4 ;  A7Z800, LUXS_BACA2 ;  C3PCE7, LUXS_BACAA ;
DR   C3LB27, LUXS_BACAC ;  A0RK18, LUXS_BACAH ;  Q81KF3, LUXS_BACAN ;
DR   B7JT57, LUXS_BACC0 ;  Q72YS4, LUXS_BACC1 ;  B7ILV4, LUXS_BACC2 ;
DR   C1EW66, LUXS_BACC3 ;  B7H9G6, LUXS_BACC4 ;  B7HTQ2, LUXS_BACC7 ;
DR   A7GU63, LUXS_BACCN ;  B9J289, LUXS_BACCQ ;  Q816N5, LUXS_BACCR ;
DR   Q632P8, LUXS_BACCZ ;  Q9K7K8, LUXS_BACHD ;  Q6HC89, LUXS_BACHK ;
DR   Q65FU5, LUXS_BACLD ;  A8FGJ6, LUXS_BACP2 ;  Q5WDW1, LUXS_BACSK ;
DR   O34667, LUXS_BACSU ;  A6KYS6, LUXS_BACV8 ;  A9VLF6, LUXS_BACWK ;
DR   A1A0P1, LUXS_BIFAA ;  B3DT87, LUXS_BIFLD ;  Q8G568, LUXS_BIFLO ;
DR   B7GUC1, LUXS_BIFLS ;  Q0SND6, LUXS_BORAP ;  O50164, LUXS_BORBU ;
DR   B7J1U9, LUXS_BORBZ ;  Q661P2, LUXS_BORGA ;  A7ZGE2, LUXS_CAMC1 ;
DR   A7GWQ0, LUXS_CAMC5 ;  A0RM88, LUXS_CAMFF ;  A7I0U3, LUXS_CAMHC ;
DR   A8FMQ4, LUXS_CAMJ8 ;  A7H2H9, LUXS_CAMJD ;  Q9PN97, LUXS_CAMJE ;
DR   Q3I354, LUXS_CAMJJ ;  Q5HTR6, LUXS_CAMJR ;  Q1QVV8, LUXS_CHRSD ;
DR   A8ANP5, LUXS_CITK8 ;  Q97F13, LUXS_CLOAB ;  A6LST9, LUXS_CLOB8 ;
DR   B2UWX8, LUXS_CLOBA ;  Q181K1, LUXS_CLOD6 ;  Q0TUQ5, LUXS_CLOP1 ;
DR   Q9XDU6, LUXS_CLOPE ;  Q0SWJ6, LUXS_CLOPS ;  C1CYB4, LUXS_DEIDV ;
DR   Q1IW42, LUXS_DEIGD ;  Q9RRU8, LUXS_DEIRA ;  C6BU86, LUXS_DESAD ;
DR   Q6AQW6, LUXS_DESPS ;  A5EVY3, LUXS_DICNV ;  A7ZQC0, LUXS_ECO24 ;
DR   B7UHB0, LUXS_ECO27 ;  B7MKG1, LUXS_ECO45 ;  B7LEA1, LUXS_ECO55 ;
DR   Q8X902, LUXS_ECO57 ;  B5Z2A2, LUXS_ECO5E ;  B7NSH2, LUXS_ECO7I ;
DR   B7MYZ0, LUXS_ECO81 ;  B7M9C9, LUXS_ECO8A ;  C4ZYT7, LUXS_ECOBW ;
DR   B1XCM0, LUXS_ECODH ;  A8A3G9, LUXS_ECOHS ;  A1AEN2, LUXS_ECOK1 ;
DR   Q0TEI8, LUXS_ECOL5 ;  Q8FEP8, LUXS_ECOL6 ;  B1IUY7, LUXS_ECOLC ;
DR   P45578, LUXS_ECOLI ;  B7N6S2, LUXS_ECOLU ;  B6I678, LUXS_ECOSE ;
DR   B1LPG2, LUXS_ECOSM ;  Q1R809, LUXS_ECOUT ;  C5BGG6, LUXS_EDWI9 ;
DR   A4WDQ1, LUXS_ENT38 ;  Q836D3, LUXS_ENTFA ;  A7MJ28, LUXS_ENTS8 ;
DR   Q6D1T5, LUXS_ERWCT ;  B7LVZ2, LUXS_ESCF3 ;  B1YKZ3, LUXS_EXIS2 ;
DR   B0S194, LUXS_FINM2 ;  Q5KVY8, LUXS_GEOKA ;  C5D6T8, LUXS_GEOSW ;
DR   A4IS03, LUXS_GEOTN ;  Q7VNV8, LUXS_HAEDU ;  Q4QN52, LUXS_HAEI8 ;
DR   A5U9Z9, LUXS_HAEIE ;  A5UH01, LUXS_HAEIG ;  P44007, LUXS_HAEIN ;
DR   B8F365, LUXS_HAEPS ;  Q0I202, LUXS_HAES1 ;  B0UVD9, LUXS_HAES2 ;
DR   Q17VY9, LUXS_HELAH ;  Q7VJR7, LUXS_HELHP ;  B6JPK6, LUXS_HELP2 ;
DR   B5Z9N6, LUXS_HELPG ;  Q1CV50, LUXS_HELPH ;  Q9ZMW8, LUXS_HELPJ ;
DR   B2URT5, LUXS_HELPS ;  O24931, LUXS_HELPY ;  B5XVC4, LUXS_KLEP3 ;
DR   Q5FK48, LUXS_LACAC ;  Q03TG6, LUXS_LACBA ;  Q03B21, LUXS_LACC3 ;
DR   B3WC53, LUXS_LACCB ;  Q1GC51, LUXS_LACDA ;  B2GE54, LUXS_LACF3 ;
DR   Q041B8, LUXS_LACGA ;  A8YXQ1, LUXS_LACH4 ;  Q74HV0, LUXS_LACJO ;
DR   Q9CIU0, LUXS_LACLA ;  A2RHY8, LUXS_LACLM ;  Q032J0, LUXS_LACLS ;
DR   Q88YI6, LUXS_LACPL ;  A5VLV3, LUXS_LACRD ;  Q5QHW1, LUXS_LACRE ;
DR   B2G970, LUXS_LACRJ ;  Q1WT73, LUXS_LACS1 ;  B1MVP6, LUXS_LEUCK ;
DR   Q03V83, LUXS_LEUMM ;  Q92C64, LUXS_LISIN ;  C1L2J6, LUXS_LISMC ;
DR   Q720D3, LUXS_LISMF ;  B8DG43, LUXS_LISMH ;  Q8Y7I9, LUXS_LISMO ;
DR   A0AI91, LUXS_LISW6 ;  B9E8I0, LUXS_MACCJ ;  Q65VI4, LUXS_MANSM ;
DR   A6VUX4, LUXS_MARMS ;  Q5F534, LUXS_NEIG1 ;  B4RRB0, LUXS_NEIG2 ;
DR   A9M0P7, LUXS_NEIM0 ;  Q9JWB0, LUXS_NEIMA ;  Q9JXL8, LUXS_NEIMB ;
DR   A1KW60, LUXS_NEIMF ;  Q8CUK0, LUXS_OCEIH ;  Q04DQ5, LUXS_OENOB ;
DR   P57901, LUXS_PASMU ;  C6DCQ4, LUXS_PECCP ;  Q03DR3, LUXS_PEDPA ;
DR   Q8KM01, LUXS_PHOLL ;  Q6LMV3, LUXS_PHOPR ;  B2RKU8, LUXS_PORG3 ;
DR   Q7MWT9, LUXS_PORGI ;  Q6AAL4, LUXS_PROAC ;  B4EUW0, LUXS_PROMH ;
DR   Q93LC7, LUXS_PROMI ;  A1SZZ2, LUXS_PSYIN ;  B5F345, LUXS_SALA4 ;
DR   A9MFZ6, LUXS_SALAR ;  Q57KV4, LUXS_SALCH ;  B5FSX3, LUXS_SALDC ;
DR   B5QV71, LUXS_SALEP ;  B5RDE7, LUXS_SALG2 ;  B4TF05, LUXS_SALHS ;
DR   B4T393, LUXS_SALNS ;  Q5PF11, LUXS_SALPA ;  C0PWL6, LUXS_SALPC ;
DR   B5BEN0, LUXS_SALPK ;  B4TSZ9, LUXS_SALSV ;  Q8Z4D7, LUXS_SALTI ;
DR   Q9L4T0, LUXS_SALTY ;  Q684Q1, LUXS_SERMA ;  A8GA14, LUXS_SERP5 ;
DR   A1S8N7, LUXS_SHEAM ;  B8EC51, LUXS_SHEB2 ;  A3D134, LUXS_SHEB5 ;
DR   A6WRX8, LUXS_SHEB8 ;  A9L0U6, LUXS_SHEB9 ;  Q12QK7, LUXS_SHEDO ;
DR   Q086L5, LUXS_SHEFN ;  B0TR04, LUXS_SHEHH ;  A3QH00, LUXS_SHELP ;
DR   Q8EHW1, LUXS_SHEON ;  A8H783, LUXS_SHEPA ;  A4Y3Y4, LUXS_SHEPC ;
DR   B8CKC3, LUXS_SHEPW ;  A0KTQ2, LUXS_SHESA ;  A8FYW3, LUXS_SHESH ;
DR   Q0HLQ3, LUXS_SHESM ;  Q0HY34, LUXS_SHESR ;  A1RN08, LUXS_SHESW ;
DR   B1KD47, LUXS_SHEWM ;  B2U054, LUXS_SHIB3 ;  Q31X57, LUXS_SHIBS ;
DR   Q32CN6, LUXS_SHIDS ;  Q0T1B8, LUXS_SHIF8 ;  Q83JZ4, LUXS_SHIFL ;
DR   Q3YYH1, LUXS_SHISS ;  Q2NVK8, LUXS_SODGM ;  A7X4Y8, LUXS_STAA1 ;
DR   A6U3L9, LUXS_STAA2 ;  Q2FEZ4, LUXS_STAA3 ;  Q2FWC3, LUXS_STAA8 ;
DR   A5IUS9, LUXS_STAA9 ;  Q2YUL9, LUXS_STAAB ;  Q5HE66, LUXS_STAAC ;
DR   A6QIX8, LUXS_STAAE ;  P65329, LUXS_STAAM ;  P65330, LUXS_STAAN ;
DR   Q6GEU1, LUXS_STAAR ;  Q6G7H6, LUXS_STAAS ;  A8YYA0, LUXS_STAAT ;
DR   P65331, LUXS_STAAW ;  B9DMC0, LUXS_STACT ;  Q5HM88, LUXS_STAEQ ;
DR   Q8CNI0, LUXS_STAES ;  Q4L815, LUXS_STAHJ ;  Q49Z80, LUXS_STAS1 ;
DR   Q3K375, LUXS_STRA1 ;  P65332, LUXS_STRA3 ;  P65333, LUXS_STRA5 ;
DR   C0M785, LUXS_STRE4 ;  Q8KQK6, LUXS_STRGC ;  Q8DVK8, LUXS_STRMU ;
DR   P0C0C8, LUXS_STRP1 ;  Q04MC2, LUXS_STRP2 ;  P0DC26, LUXS_STRP3 ;
DR   B5E784, LUXS_STRP4 ;  Q5XAN3, LUXS_STRP6 ;  C1CBB9, LUXS_STRP7 ;
DR   P0A3P9, LUXS_STRP8 ;  Q1JAI5, LUXS_STRPB ;  Q1JKN7, LUXS_STRPC ;
DR   Q1JFM8, LUXS_STRPD ;  Q1J5H8, LUXS_STRPF ;  A2RD59, LUXS_STRPG ;
DR   B1I959, LUXS_STRPI ;  B8ZL57, LUXS_STRPJ ;  Q48S10, LUXS_STRPM ;
DR   P65334, LUXS_STRPN ;  P0DC27, LUXS_STRPQ ;  B2ISQ8, LUXS_STRPS ;
DR   P0C0C7, LUXS_STRPY ;  B5XMJ4, LUXS_STRPZ ;  P65335, LUXS_STRR6 ;
DR   A4VZM6, LUXS_STRS2 ;  C0MH25, LUXS_STRS7 ;  A3CPX9, LUXS_STRSV ;
DR   A4VTE8, LUXS_STRSY ;  Q5M173, LUXS_STRT1 ;  Q5M5R0, LUXS_STRT2 ;
DR   Q03M44, LUXS_STRTD ;  B9DV56, LUXS_STRU0 ;  C1CCB3, LUXS_STRZJ ;
DR   C1CIK5, LUXS_STRZP ;  C1CPL5, LUXS_STRZT ;  Q30P69, LUXS_SULDN ;
DR   A6Q6Q3, LUXS_SULNB ;  Q72IE6, LUXS_THET2 ;  Q5SI29, LUXS_THET8 ;
DR   Q31DQ6, LUXS_THICR ;  C4LCK3, LUXS_TOLAT ;  Q6TP45, LUXS_VIBAL ;
DR   A5F9A3, LUXS_VIBC3 ;  Q9KUG4, LUXS_VIBCH ;  C3LS47, LUXS_VIBCM ;
DR   B5FAE1, LUXS_VIBFM ;  Q9Z5X1, LUXS_VIBHB ;  Q87LS4, LUXS_VIBPA ;
DR   B7VK33, LUXS_VIBSL ;  Q9AHK1, LUXS_VIBVU ;  Q7MHS7, LUXS_VIBVY ;
DR   Q7MQP3, LUXS_WOLSU ;  A1JK16, LUXS_YERE8 ;  A7FLR2, LUXS_YERP3 ;
DR   Q1C416, LUXS_YERPA ;  B2K5Y4, LUXS_YERPB ;  Q8ZBU3, LUXS_YERPE ;
DR   A9R0V3, LUXS_YERPG ;  Q1CLK4, LUXS_YERPN ;  A4TQ57, LUXS_YERPP ;
DR   Q66E63, LUXS_YERPS ;  B1JJ95, LUXS_YERPY ;
//
ID   4.4.1.22
DE   S-(hydroxymethyl)glutathione synthase.
AN   Glutathione-dependent formaldehyde-activating enzyme.
CA   S-(hydroxymethyl)glutathione = glutathione + formaldehyde.
CC   -!- The enzyme from Paracoccus denitrificans accelerates the spontaneous
CC       reaction in which the adduct of formaldehyde and glutathione is
CC       formed, i.e. the substrate for EC 1.1.1.284, in the formaldehyde-
CC       detoxification pathway.
CC   -!- Formerly EC 1.2.1.1.
DR   B8NDP1, GFA_ASPFN  ;  A2QBH6, GFA_ASPNC  ;  P0CL54, GFA_ASPOR  ;
DR   Q0CMY6, GFA_ASPTN  ;  Q89GX9, GFA_BRAJA  ;  A5EP16, GFA_BRASB  ;
DR   A4YZ37, GFA_BRASO  ;  E3QRY8, GFA_COLGM  ;  C8VDQ3, GFA_EMENI  ;
DR   C7Z147, GFA_NECH7  ;  Q51669, GFA_PARDE  ;  A1AXY8, GFA_PARDP  ;
DR   B6HE56, GFA_PENCW  ;  B6QNA1, GFA_PENMQ  ;  Q0V314, GFA_PHANO  ;
DR   B2ACV0, GFA_PODAN  ;  B2W9N9, GFA_PYRTR  ;  E3S405, GFA_PYRTT  ;
DR   Q98LU4, GFA_RHILO  ;  Q92WX6, GFA_RHIME  ;  Q07HI5, GFA_RHOP5  ;
DR   Q21D57, GFA_RHOPB  ;  D1ZK87, GFA_SORMK  ;  C9S7Z6, GFA_VERA1  ;
DR   Q8PPF1, GFA_XANAC  ;  Q3BXJ3, GFA_XANC5  ;  Q4UYL9, GFA_XANC8  ;
DR   B0RNW7, GFA_XANCB  ;  Q8P5F3, GFA_XANCP  ;
//
ID   4.4.1.23
DE   2-hydroxypropyl-CoM lyase.
AN   Coenzyme M-epoxyalkane ligase.
AN   EaCoMT.
CA   (1) (R)-2-hydroxypropyl-CoM = (R)-1,2-epoxypropane + HS-CoM.
CA   (2) (S)-2-hydroxypropyl-CoM = (S)-1,2-epoxypropane + HS-CoM.
CF   Zinc.
CC   -!- Acts on both enantiomers of chiral epoxyalkanes to form the
CC       corresponding (R)- and (S)-2-hydroxyalkyl-CoM adducts.
CC   -!- The enzyme will function with some other thiols (e.g.,
CC       2-sulfanylethanol) as the nucleophile.
CC   -!- Uses short-chain epoxyalkanes from C(2) (epoxyethane) to C(6) (1,2-
CC       epoxyhexane).
CC   -!- This enzyme forms component I of a four-component enzyme system
CC       (comprising EC 4.4.1.23 (component I), EC 1.8.1.5 (component II),
CC       EC 1.1.1.268 (component III) and EC 1.1.1.269 (component IV)) that is
CC       involved in epoxyalkane carboxylation in Xanthobacter sp. strain Py2.
CC   -!- Formerly EC 4.2.99.19.
DR   Q56837, XECA_XANP2 ;
//
ID   4.4.1.24
DE   Sulfolactate sulfo-lyase.
CA   3-sulfolactate = pyruvate + bisulfite.
CF   Fe(2+).
CC   -!- The inducible enzyme from Paracoccus pantotrophus NKNCYSA forms part
CC       of the cysteate-degradation pathway.
CC   -!- L-cysteate ((2S)2-amino-3-sulfopropanoate) serves as a sole source of
CC       carbon and energy for the aerobic growth of P.pantotrophus, as an
CC       electron acceptor for several sulfate-reducing bacteria, as an
CC       electron donor for some nitrate-reducing bacteria and as a substrate
CC       for a fermentation in a sulfate-reducing baterium.
//
ID   4.4.1.25
DE   L-cysteate sulfo-lyase.
CA   L-cysteate + H(2)O = pyruvate + bisulfite + NH(3).
CF   Pyridoxal 5'-phosphate.
CC   -!- D-cysteine can also act as a substrate, but more slowly.
CC   -!- It is converted into pyruvate, sulfide and NH(3).
CC   -!- The inducible enzyme from Silicibacter pomeroyi DSS-3 forms part of
CC       the cysteate-degradation pathway.
//
ID   4.5.1.1
DE   DDT-dehydrochlorinase.
CA   1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-
CA   bis(4-chlorophenyl)ethylene + chloride.
DR   Q93112, GST1C_ANOGA;  Q93113, GST1D_ANOGA;  P30104, GSTT1_DROER;
DR   P67804, GSTT1_DROMA;  P20432, GSTT1_DROME;  P30106, GSTT1_DROSE;
DR   P67805, GSTT1_DROSI;  P30107, GSTT1_DROTE;
//
ID   4.5.1.2
DE   3-chloro-D-alanine dehydrochlorinase.
CA   3-chloro-D-alanine + H(2)O = pyruvate + HCl + NH(3).
CF   Pyridoxal 5'-phosphate.
CC   -!- Also catalyzes beta-replacement reactions, e.g. converts 3-chloro-D-
CC       alanine and H(2)S into D-cysteine and HCl.
//
ID   4.5.1.3
DE   Dichloromethane dehalogenase.
CA   Dichloromethane + H(2)O = formaldehyde + 2 HCl.
CF   Glutathione.
DR   P21161, DCMA_METED ;  P43387, DCMA_METS1 ;
//
ID   4.5.1.4
DE   L-2-amino-4-chloropent-4-enoate dehydrochlorinase.
CA   L-2-amino-4-chloropent-4-enoate + H(2)O = 2-oxopent-4-enoate + HCl +
CA   NH(3).
//
ID   4.5.1.5
DE   S-carboxymethylcysteine synthase.
CA   3-chloro-L-alanine + thioglycolate = S-carboxymethyl-L-cysteine +
CA   chloride.
CF   Pyridoxal 5'-phosphate.
//
ID   4.6.1.1
DE   Adenylate cyclase.
AN   3',5'-cyclic AMP synthetase.
AN   Adenyl cyclase.
AN   Adenylyl cyclase.
AN   ATP pyrophosphate-lyase.
CA   ATP = 3',5'-cyclic AMP + diphosphate.
CC   -!- Also acts on dATP to form 3',5'-cyclic dAMP.
CC   -!- Requires pyruvate.
CC   -!- Activated by NAD(+) in presence of EC 2.4.2.31.
PR   PROSITE; PDOC00425;
PR   PROSITE; PDOC00837;
DR   P83855, ACLP_MOUSE ;  P19754, ADCY1_BOVIN;  Q08828, ADCY1_HUMAN;
DR   O88444, ADCY1_MOUSE;  Q9VW60, ADCY2_DROME;  Q08462, ADCY2_HUMAN;
DR   Q80TL1, ADCY2_MOUSE;  P26769, ADCY2_RAT  ;  O60266, ADCY3_HUMAN;
DR   Q8VHH7, ADCY3_MOUSE;  P21932, ADCY3_RAT  ;  Q8NFM4, ADCY4_HUMAN;
DR   Q91WF3, ADCY4_MOUSE;  P26770, ADCY4_RAT  ;  P30803, ADCY5_CANFA;
DR   O95622, ADCY5_HUMAN;  P84309, ADCY5_MOUSE;  P40144, ADCY5_RABIT;
DR   Q04400, ADCY5_RAT  ;  P30804, ADCY6_CANFA;  O43306, ADCY6_HUMAN;
DR   Q01341, ADCY6_MOUSE;  Q03343, ADCY6_RAT  ;  Q29450, ADCY7_BOVIN;
DR   P51828, ADCY7_HUMAN;  P51829, ADCY7_MOUSE;  P40145, ADCY8_HUMAN;
DR   P97490, ADCY8_MOUSE;  P40146, ADCY8_RAT  ;  Q9DGG6, ADCY9_CHICK;
DR   O60503, ADCY9_HUMAN;  P51830, ADCY9_MOUSE;  P98999, ADCY9_XENLA;
DR   Q96PN6, ADCYA_HUMAN;  Q8C0T9, ADCYA_MOUSE;  Q866F4, ADCYA_RABIT;
DR   Q9Z286, ADCYA_RAT  ;  Q99279, CY41_TRYBB ;  Q99396, CY42_TRYBB ;
DR   Q99280, CY43_TRYBB ;  P32870, CYA1_DROME ;  P0A4Y1, CYA1_MYCBO ;
DR   P0A4Y0, CYA1_MYCTU ;  P19485, CYA1_RHIME ;  Q52915, CYA2_RHIME ;
DR   Q9Z3Q0, CYA3_RHIME ;  Q26721, CYA4_TRYBB ;  Q59119, CYAA_AERHY ;
DR   P43524, CYAA_ANACY ;  P40136, CYAA_BACAN ;  Q57506, CYAA_BORBR ;
DR   P15318, CYAA_BORPE ;  P27580, CYAA_BRELI ;  Q03100, CYAA_DICDI ;
DR   Q8XAP1, CYAA_ECO57 ;  Q8FBP0, CYAA_ECOL6 ;  P00936, CYAA_ECOLI ;
DR   P40130, CYAA_ERWCH ;  P40134, CYAA_HAEIN ;  Q27675, CYAA_LEIDO ;
DR   Q01631, CYAA_NEUCR ;  Q05766, CYAA_PASMU ;  Q01513, CYAA_PODAS ;
DR   Q59685, CYAA_PROMI ;  P23466, CYAA_SACKL ;  P0A1A8, CYAA_SALTI ;
DR   P0A1A7, CYAA_SALTY ;  P14605, CYAA_SCHPO ;  P59739, CYAA_SHIFL ;
DR   P40137, CYAA_STIAU ;  P40135, CYAA_STRCO ;  Q9WXC3, CYAA_STRGR ;
DR   Q26896, CYAA_TRYCO ;  P26338, CYAA_TRYEQ ;  P49606, CYAA_USTMA ;
DR   P08678, CYAA_YEAST ;  P30528, CYAA_YERIN ;  P40127, CYAA_YERPE ;
DR   Q25263, CYAB_LEIDO ;  P40138, CYAB_STIAU ;  Q55F68, CYAD_DICDI ;
DR   Q03101, CYAG_DICDI ;  Q76L34, PCYAA_ASTLO;  Q8S9F2, PCYAA_EUGGR;
DR   Q76L33, PCYAB_ASTLO;  Q8S9F1, PCYAB_EUGGR;  Q11055, Y1264_MYCTU;
//
ID   4.6.1.2
DE   Guanylate cyclase.
AN   Guanyl cyclase.
AN   Guanylyl cyclase.
CA   GTP = 3',5'-cyclic GMP + diphosphate.
CC   -!- Also acts on ITP and dGTP.
PR   PROSITE; PDOC00425;
DR   P16066, ANPRA_HUMAN;  P18293, ANPRA_MOUSE;  P18910, ANPRA_RAT  ;
DR   P55202, ANPRB_ANGJA;  P46197, ANPRB_BOVIN;  P20594, ANPRB_HUMAN;
DR   Q6VVW5, ANPRB_MOUSE;  P16067, ANPRB_RAT  ;  Q553Y7, GCA_DICDI  ;
DR   Q09435, GCY1_CAEEL ;  Q86C56, GCY31_CAEEL;  Q6DNF7, GCY32_CAEEL;
DR   P90895, GCY33_CAEEL;  P92006, GCY34_CAEEL;  O02298, GCY35_CAEEL;
DR   Q6DNF4, GCY36_CAEEL;  Q6DNF3, GCY37_CAEEL;  Q07553, GCY3E_DROME;
DR   Q8INF0, GCY8E_DROME;  P19687, GCYA1_BOVIN;  P33402, GCYA2_HUMAN;
DR   Q9WVI4, GCYA2_RAT  ;  Q4ZHS0, GCYA3_CANFA;  Q02108, GCYA3_HUMAN;
DR   Q9ERL9, GCYA3_MOUSE;  P19686, GCYA3_RAT  ;  P16068, GCYB1_BOVIN;
DR   Q4ZHR9, GCYB1_CANFA;  Q02153, GCYB1_HUMAN;  O54865, GCYB1_MOUSE;
DR   P20595, GCYB1_RAT  ;  O75343, GCYB2_HUMAN;  P22717, GCYB2_RAT  ;
DR   Q9VEU6, GCYDA_DROME;  Q9VEU5, GCYDB_DROME;  Q07093, GCYH_DROME ;
DR   P11528, GCY_ARBPU  ;  P16065, GCY_STRPU  ;  P70106, GUC2C_CAVPO;
DR   P25092, GUC2C_HUMAN;  Q3UWA6, GUC2C_MOUSE;  P55204, GUC2C_PIG  ;
DR   P23897, GUC2C_RAT  ;  P55203, GUC2D_BOVIN;  O19179, GUC2D_CANFA;
DR   Q02846, GUC2D_HUMAN;  P51839, GUC2D_RAT  ;  P52785, GUC2E_MOUSE;
DR   P51840, GUC2E_RAT  ;  O02740, GUC2F_BOVIN;  P51841, GUC2F_HUMAN;
DR   Q5SDA5, GUC2F_MOUSE;  P51842, GUC2F_RAT  ;  Q6TL19, GUC2G_MOUSE;
DR   P55205, GUC2G_RAT  ;
//
ID   4.6.1.3
DE   Transferred entry: 4.2.3.4.
//
ID   4.6.1.4
DE   Transferred entry: 4.2.3.5.
//
ID   4.6.1.5
DE   Transferred entry: 4.2.3.7.
//
ID   4.6.1.6
DE   Cytidylate cyclase.
AN   3'5'-cyclic-CMP synthase.
AN   Cytidyl cyclase.
AN   Cytidylyl cyclase.
CA   CTP = 3',5'-cyclic CMP + diphosphate.
//
ID   4.6.1.7
DE   Transferred entry: 4.2.3.8.
//
ID   4.6.1.8
DE   Transferred entry: 4.2.3.10.
//
ID   4.6.1.9
DE   Transferred entry: 4.2.3.11.
//
ID   4.6.1.10
DE   Transferred entry: 4.2.3.12.
//
ID   4.6.1.11
DE   Transferred entry: 4.2.3.13.
//
ID   4.6.1.12
DE   2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase.
AN   MECDP-synthase.
CA   2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl-
CA   D-erythritol 2,4-cyclodiphosphate + CMP.
CF   Manganese or magnesium.
CC   -!- Forms part of an alternative nonmevalonate pathway for terpenoid
CC       biosynthesis.
PR   PROSITE; PDOC01048;
DR   B9JF01, ISPDF_AGRRK;  Q8UFF4, ISPDF_AGRT5;  B9JW91, ISPDF_AGRVS;
DR   Q2IQG8, ISPDF_ANADE;  A7HDA2, ISPDF_ANADF;  A8ER37, ISPDF_ARCB4;
DR   A8IBL6, ISPDF_AZOC5;  A1USA2, ISPDF_BARBK;  Q6G3Z8, ISPDF_BARHE;
DR   Q6G164, ISPDF_BARQU;  A9IS87, ISPDF_BART1;  Q89LQ8, ISPDF_BRAJA;
DR   A5EIY9, ISPDF_BRASB;  A4YUQ7, ISPDF_BRASO;  Q2YPW1, ISPDF_BRUA2;
DR   Q57D18, ISPDF_BRUAB;  Q8YHD8, ISPDF_BRUME;  A5VQP4, ISPDF_BRUO2;
DR   Q8G0H4, ISPDF_BRUSU;  A7ZCQ2, ISPDF_CAMC1;  A7GZI1, ISPDF_CAMC5;
DR   A0RN28, ISPDF_CAMFF;  A7I1V2, ISPDF_CAMHC;  A8FNR8, ISPDF_CAMJ8;
DR   A7H5V8, ISPDF_CAMJD;  Q9PM68, ISPDF_CAMJE;  A1W1K9, ISPDF_CAMJJ;
DR   Q5HSI4, ISPDF_CAMJR;  B9KEX3, ISPDF_CAMLR;  B8GW85, ISPDF_CAUCN;
DR   Q9A7I5, ISPDF_CAUCR;  A5CTY4, ISPDF_CLAM3;  B1I0S9, ISPDF_DESAP;
DR   Q310X3, ISPDF_DESDG;  C4XSW4, ISPDF_DESMR;  Q6ARN9, ISPDF_DESPS;
DR   Q72C30, ISPDF_DESVH;  A1VDX6, ISPDF_DESVV;  A8LKV5, ISPDF_DINSH;
DR   Q2NAE1, ISPDF_ERYLH;  Q5FQD6, ISPDF_GLUOX;  Q0BTD5, ISPDF_GRABC;
DR   Q17WU1, ISPDF_HELAH;  Q7VFU3, ISPDF_HELHP;  B6JL03, ISPDF_HELP2;
DR   B5Z6H4, ISPDF_HELPG;  Q1CU78, ISPDF_HELPH;  Q9ZM19, ISPDF_HELPJ;
DR   B2USR1, ISPDF_HELPS;  O25664, ISPDF_HELPY;  Q0C0N0, ISPDF_HYPNA;
DR   Q28Q60, ISPDF_JANSC;  Q1MR76, ISPDF_LAWIP;  Q6ADI0, ISPDF_LEIXX;
DR   Q2W4Q8, ISPDF_MAGSA;  Q0APQ6, ISPDF_MARMM;  Q11HV9, ISPDF_MESSB;
DR   Q1QM99, ISPDF_NITHX;  A6Q2K0, ISPDF_NITSB;  Q3SSN8, ISPDF_NITWN;
DR   Q2G708, ISPDF_NOVAD;  A6X0N1, ISPDF_OCHA4;  A1B890, ISPDF_PARDP;
DR   A7HXV6, ISPDF_PARL1;  Q4FM31, ISPDF_PELUB;  B3PYS4, ISPDF_RHIE6;
DR   Q2K8V5, ISPDF_RHIEC;  Q1MH21, ISPDF_RHIL3;  Q98MX9, ISPDF_RHILO;
DR   B5ZNB6, ISPDF_RHILW;  Q92Q90, ISPDF_RHIME;  Q08113, ISPDF_RHOCB;
DR   Q21YT7, ISPDF_RHOFD;  Q2IW23, ISPDF_RHOP2;  Q07MZ2, ISPDF_RHOP5;
DR   Q6N6M5, ISPDF_RHOPA;  Q214R1, ISPDF_RHOPB;  Q137C3, ISPDF_RHOPS;
DR   B3QIL5, ISPDF_RHOPT;  Q2RTS1, ISPDF_RHORT;  Q5LRN5, ISPDF_SILPO;
DR   Q1GGW9, ISPDF_SILST;  A6U8F8, ISPDF_SINMW;  Q1GTN0, ISPDF_SPHAL;
DR   A5V2U9, ISPDF_SPHWW;  Q30QG7, ISPDF_SULDN;  A6Q7M3, ISPDF_SULNB;
DR   O83525, ISPDF_TREPA;  Q83NK3, ISPDF_TROW8;  Q83MX3, ISPDF_TROWT;
DR   Q73G24, ISPDF_WOLPM;  Q7MQW9, ISPDF_WOLSU;  Q5GSM7, ISPDF_WOLTR;
DR   Q9RNZ1, ISPDF_ZYMMO;  B0CBC9, ISPF_ACAM1 ;  Q6FAU4, ISPF_ACIAD ;
DR   B7H1F3, ISPF_ACIB3 ;  B7I9W0, ISPF_ACIB5 ;  B2I336, ISPF_ACIBC ;
DR   Q1IVA8, ISPF_ACIBL ;  B0VMT6, ISPF_ACIBS ;  A3M665, ISPF_ACIBT ;
DR   B0V6G3, ISPF_ACIBY ;  A0LQZ7, ISPF_ACIC1 ;  A3N0G3, ISPF_ACTP2 ;
DR   B3H1E2, ISPF_ACTP7 ;  B0BP83, ISPF_ACTPJ ;  A6VQY0, ISPF_ACTSZ ;
DR   B2URI3, ISPF_AKKM8 ;  Q0VQD3, ISPF_ALCBS ;  Q0A7K7, ISPF_ALHEH ;
DR   B6EKL5, ISPF_ALISL ;  A6TWK9, ISPF_ALKMQ ;  A8MLB2, ISPF_ALKOO ;
DR   Q5P993, ISPF_ANAMM ;  Q2GIK8, ISPF_ANAPZ ;  B9MRD4, ISPF_ANATD ;
DR   Q3MC53, ISPF_ANAVT ;  O67089, ISPF_AQUAE ;  Q9CAK8, ISPF_ARATH ;
DR   Q5NYK0, ISPF_AROAE ;  B8HCR6, ISPF_ARTCA ;  B6YRV8, ISPF_AZOPC ;
DR   A1K645, ISPF_AZOSB ;  C1DSS0, ISPF_AZOVD ;  A7Z0L3, ISPF_BACA2 ;
DR   C3P9N2, ISPF_BACAA ;  C3LJ59, ISPF_BACAC ;  A0R8F8, ISPF_BACAH ;
DR   Q81VV4, ISPF_BACAN ;  B7JK94, ISPF_BACC0 ;  Q73FC0, ISPF_BACC1 ;
DR   B7ISZ6, ISPF_BACC2 ;  C1ET16, ISPF_BACC3 ;  B7HJ25, ISPF_BACC4 ;
DR   B7HQS1, ISPF_BACC7 ;  A7GJZ8, ISPF_BACCN ;  B9IZH1, ISPF_BACCQ ;
DR   Q81J62, ISPF_BACCR ;  Q63HB3, ISPF_BACCZ ;  Q5L8X2, ISPF_BACFN ;
DR   Q64P34, ISPF_BACFR ;  Q9KGF7, ISPF_BACHD ;  Q6HPT1, ISPF_BACHK ;
DR   Q65PD1, ISPF_BACLD ;  A8F959, ISPF_BACP2 ;  Q5WLT6, ISPF_BACSK ;
DR   Q06756, ISPF_BACSU ;  Q8A0Y7, ISPF_BACTN ;  A6L0V6, ISPF_BACV8 ;
DR   A9VN99, ISPF_BACWK ;  Q8G5L2, ISPF_BIFLO ;  B7GT04, ISPF_BIFLS ;
DR   Q493M8, ISPF_BLOPB ;  Q2KUX6, ISPF_BORA1 ;  Q7WCW4, ISPF_BORBR ;
DR   Q7W5D0, ISPF_BORPA ;  A9II47, ISPF_BORPD ;  Q7VZN1, ISPF_BORPE ;
DR   C0R0Y4, ISPF_BRAHW ;  B8D9J7, ISPF_BUCA5 ;  P57494, ISPF_BUCAI ;
DR   Q8K9D7, ISPF_BUCAP ;  B8D7U9, ISPF_BUCAT ;  B1YS10, ISPF_BURA4 ;
DR   Q1BHA4, ISPF_BURCA ;  B1JTX0, ISPF_BURCC ;  A0K866, ISPF_BURCH ;
DR   B4EC22, ISPF_BURCJ ;  Q0BED7, ISPF_BURCM ;  A9AIT6, ISPF_BURM1 ;
DR   A3MKM3, ISPF_BURM7 ;  A2SBD7, ISPF_BURM9 ;  Q62JI6, ISPF_BURMA ;
DR   A1V4Z9, ISPF_BURMS ;  A3NWD9, ISPF_BURP0 ;  Q3JRA0, ISPF_BURP1 ;
DR   A3NAL8, ISPF_BURP6 ;  B2JGK3, ISPF_BURP8 ;  B2T3X3, ISPF_BURPP ;
DR   Q63T71, ISPF_BURPS ;  Q39FB9, ISPF_BURS3 ;  Q2SWT5, ISPF_BURTA ;
DR   A4JF19, ISPF_BURVG ;  Q13Z30, ISPF_BURXL ;  A4XJU4, ISPF_CALS8 ;
DR   Q3A9N8, ISPF_CARHZ ;  Q9M4W3, ISPF_CATRO ;  B3PJB0, ISPF_CELJU ;
DR   Q5L6S2, ISPF_CHLAB ;  Q3APP2, ISPF_CHLCH ;  Q824F7, ISPF_CHLCV ;
DR   Q253F4, ISPF_CHLFF ;  Q9PJV8, ISPF_CHLMU ;  B3QPS3, ISPF_CHLP8 ;
DR   B3EMU1, ISPF_CHLPB ;  A1BE20, ISPF_CHLPD ;  Q9Z805, ISPF_CHLPN ;
DR   B0B806, ISPF_CHLT2 ;  B3QV82, ISPF_CHLT3 ;  Q3KLR6, ISPF_CHLTA ;
DR   B0BC71, ISPF_CHLTB ;  Q8KC25, ISPF_CHLTE ;  O84441, ISPF_CHLTR ;
DR   Q1QU74, ISPF_CHRSD ;  Q7NYL5, ISPF_CHRVO ;  A8ANW0, ISPF_CITK8 ;
DR   Q97LX0, ISPF_CLOAB ;  A7FQ95, ISPF_CLOB1 ;  C3KXW6, ISPF_CLOB6 ;
DR   A6LQ55, ISPF_CLOB8 ;  B2UYW8, ISPF_CLOBA ;  B2TIU0, ISPF_CLOBB ;
DR   A5HXW3, ISPF_CLOBH ;  C1FQ26, ISPF_CLOBJ ;  B1ID41, ISPF_CLOBK ;
DR   A7G9H1, ISPF_CLOBL ;  B1KRX5, ISPF_CLOBM ;  Q18CD3, ISPF_CLOD6 ;
DR   B9DXE4, ISPF_CLOK1 ;  A5N3R3, ISPF_CLOK5 ;  A0Q3K0, ISPF_CLONN ;
DR   Q0TMY4, ISPF_CLOP1 ;  Q8XI08, ISPF_CLOPE ;  Q0SQN0, ISPF_CLOPS ;
DR   Q899E9, ISPF_CLOTE ;  Q487E8, ISPF_COLP3 ;  Q6NFC2, ISPF_CORDI ;
DR   Q8FMI4, ISPF_COREF ;  A4QH59, ISPF_CORGB ;  Q8NMB9, ISPF_CORGL ;
DR   Q4JXJ6, ISPF_CORJK ;  B1VIQ0, ISPF_CORU7 ;  Q0KBM9, ISPF_CUPNH ;
DR   Q472F1, ISPF_CUPPJ ;  B3R4U4, ISPF_CUPTR ;  B8HVI5, ISPF_CYAP4 ;
DR   Q11Q93, ISPF_CYTH3 ;  Q47EL1, ISPF_DECAR ;  Q3ZAD6, ISPF_DEHE1 ;
DR   Q3ZWG5, ISPF_DEHSC ;  Q9RXS6, ISPF_DEIRA ;  B8FHQ6, ISPF_DESAA ;
DR   B8G1T9, ISPF_DESHD ;  Q250Q9, ISPF_DESHY ;  A9A0H0, ISPF_DESOH ;
DR   A4J0Y4, ISPF_DESRM ;  A7ZQJ0, ISPF_ECO24 ;  B7UHG5, ISPF_ECO27 ;
DR   B7MKM0, ISPF_ECO45 ;  B7LEG4, ISPF_ECO55 ;  P62618, ISPF_ECO57 ;
DR   B5Z3A8, ISPF_ECO5E ;  B7NT90, ISPF_ECO7I ;  B7MZ47, ISPF_ECO81 ;
DR   B7LXF8, ISPF_ECO8A ;  C4ZZQ0, ISPF_ECOBW ;  B1XCS2, ISPF_ECODH ;
DR   A8A3M5, ISPF_ECOHS ;  A1AEU0, ISPF_ECOK1 ;  Q0TEB2, ISPF_ECOL5 ;
DR   Q8FEJ6, ISPF_ECOL6 ;  B1IUT3, ISPF_ECOLC ;  P62617, ISPF_ECOLI ;
DR   B7N6X6, ISPF_ECOLU ;  B6I6D6, ISPF_ECOSE ;  B1LQ66, ISPF_ECOSM ;
DR   Q1R7U5, ISPF_ECOUT ;  C5BGJ0, ISPF_EDWI9 ;  Q3YT02, ISPF_EHRCJ ;
DR   Q2GHV0, ISPF_EHRCR ;  Q5FF92, ISPF_EHRRG ;  Q5HC74, ISPF_EHRRW ;
DR   A4WDV1, ISPF_ENT38 ;  Q839V8, ISPF_ENTFA ;  A7MJ58, ISPF_ENTS8 ;
DR   Q6D1B4, ISPF_ERWCT ;  B2VFZ6, ISPF_ERWT9 ;  B7LWK9, ISPF_ESCF3 ;
DR   C4Z3N3, ISPF_EUBE2 ;  C4Z8W9, ISPF_EUBR3 ;  B0S2Q7, ISPF_FINM2 ;
DR   Q0RBN8, ISPF_FRAAA ;  B0TYX5, ISPF_FRAP2 ;  Q2J543, ISPF_FRASC ;
DR   A8LF85, ISPF_FRASN ;  Q14H93, ISPF_FRAT1 ;  A7NBK5, ISPF_FRATF ;
DR   Q2A3Z7, ISPF_FRATH ;  B2SDD4, ISPF_FRATM ;  A0Q6Y1, ISPF_FRATN ;
DR   Q0BMD2, ISPF_FRATO ;  Q5NFU1, ISPF_FRATT ;  A4IYG6, ISPF_FRATW ;
DR   Q8R6E7, ISPF_FUSNN ;  C1A8W3, ISPF_GEMAT ;  Q5L432, ISPF_GEOKA ;
DR   B3E280, ISPF_GEOLS ;  Q39ZL6, ISPF_GEOMG ;  B9LZW2, ISPF_GEOSF ;
DR   Q747A0, ISPF_GEOSL ;  C5D3P3, ISPF_GEOSW ;  A4IJG5, ISPF_GEOTN ;
DR   A5G939, ISPF_GEOUR ;  Q7NFH8, ISPF_GLOVI ;  Q47956, ISPF_HAEDU ;
DR   Q4QMP5, ISPF_HAEI8 ;  A5UE60, ISPF_HAEIE ;  A5UHG0, ISPF_HAEIG ;
DR   P44815, ISPF_HAEIN ;  B8F4V8, ISPF_HAEPS ;  Q0I5H9, ISPF_HAES1 ;
DR   B0URU8, ISPF_HAES2 ;  Q2SKW6, ISPF_HAHCH ;  A1WWY9, ISPF_HALHL ;
DR   B8D0A0, ISPF_HALOH ;  B4U9N6, ISPF_HYDS0 ;  Q5QUC4, ISPF_IDILO ;
DR   A6W6E9, ISPF_KINRD ;  B5XV35, ISPF_KLEP3 ;  A6TD38, ISPF_KLEP7 ;
DR   C5CGG7, ISPF_KOSOT ;  C1D559, ISPF_LARHH ;  B0SAT2, ISPF_LEPBA ;
DR   Q04VM3, ISPF_LEPBJ ;  Q04XV1, ISPF_LEPBL ;  B0SJL7, ISPF_LEPBP ;
DR   Q72UP7, ISPF_LEPIC ;  Q8F0A5, ISPF_LEPIN ;  Q92F39, ISPF_LISIN ;
DR   C1KYG9, ISPF_LISMC ;  Q724H6, ISPF_LISMF ;  B8DF19, ISPF_LISMH ;
DR   Q8YAB4, ISPF_LISMO ;  B1HNM6, ISPF_LYSSC ;  Q65Q79, ISPF_MANSM ;
DR   A1TZ51, ISPF_MARAV ;  Q604M1, ISPF_METCA ;  Q1H2A2, ISPF_METFK ;
DR   Q2RFM1, ISPF_MOOTA ;  A0QAB4, ISPF_MYCA1 ;  B1MGY4, ISPF_MYCA9 ;
DR   P65184, ISPF_MYCBO ;  A1KPR7, ISPF_MYCBP ;  C1AI40, ISPF_MYCBT ;
DR   Q7NC56, ISPF_MYCGA ;  B8ZUA8, ISPF_MYCLB ;  Q9CCW5, ISPF_MYCLE ;
DR   B2HJ22, ISPF_MYCMM ;  Q743W4, ISPF_MYCPA ;  A5U8Q6, ISPF_MYCTA ;
DR   P65183, ISPF_MYCTU ;  A1TG10, ISPF_MYCVP ;  B2A4B2, ISPF_NATTJ ;
DR   Q5F830, ISPF_NEIG1 ;  A9M0U6, ISPF_NEIM0 ;  Q9JTM4, ISPF_NEIMA ;
DR   Q9JYM5, ISPF_NEIMB ;  A1KUU9, ISPF_NEIMF ;  Q2GER2, ISPF_NEOSM ;
DR   Q0AGI1, ISPF_NITEC ;  Q82US7, ISPF_NITEU ;  Q2Y752, ISPF_NITMU ;
DR   Q3JCS8, ISPF_NITOC ;  Q5Z2R2, ISPF_NOCFA ;  A1SNY6, ISPF_NOCSJ ;
DR   B2JA49, ISPF_NOSP7 ;  Q8YQF0, ISPF_NOSS1 ;  A6LF29, ISPF_PARD8 ;
DR   P57954, ISPF_PASMU ;  C6DDG1, ISPF_PECCP ;  Q3A8C7, ISPF_PELCD ;
DR   Q3B2H9, ISPF_PELLD ;  B4SE23, ISPF_PELPB ;  A1AJY3, ISPF_PELPD ;
DR   A5D5L5, ISPF_PELTS ;  A9BHL8, ISPF_PETMO ;  Q7N8K6, ISPF_PHOLL ;
DR   Q6LMT4, ISPF_PHOPR ;  P62368, ISPF_PLAF7 ;  P62369, ISPF_PLAFX ;
DR   B2RGP8, ISPF_PORG3 ;  Q7MXX0, ISPF_PORGI ;  B4S5L1, ISPF_PROA2 ;
DR   Q6AAV7, ISPF_PROAC ;  A8G687, ISPF_PROM2 ;  Q319L1, ISPF_PROM9 ;
DR   B4F226, ISPF_PROMH ;  A4SFZ0, ISPF_PROVI ;  Q48F85, ISPF_PSE14 ;
DR   Q15P30, ISPF_PSEA6 ;  A6V1G1, ISPF_PSEA7 ;  B7V8C1, ISPF_PSEA8 ;
DR   Q02R99, ISPF_PSEAB ;  P57708, ISPF_PSEAE ;  Q1I652, ISPF_PSEE4 ;
DR   Q4KHF0, ISPF_PSEF5 ;  C3K703, ISPF_PSEFS ;  Q3IDQ5, ISPF_PSEHT ;
DR   A4XWR4, ISPF_PSEMY ;  A5W823, ISPF_PSEP1 ;  Q3KH86, ISPF_PSEPF ;
DR   B0KSC5, ISPF_PSEPG ;  Q88MF3, ISPF_PSEPK ;  B1JB32, ISPF_PSEPW ;
DR   Q886L7, ISPF_PSESM ;  Q4ZWQ2, ISPF_PSEU2 ;  A4VJV0, ISPF_PSEU5 ;
DR   Q4FSB5, ISPF_PSYA2 ;  Q1QBM3, ISPF_PSYCK ;  Q1LLZ4, ISPF_RALME ;
DR   B2UFT6, ISPF_RALPJ ;  Q8XYW2, ISPF_RALSO ;  Q7UU80, ISPF_RHOBA ;
DR   C0ZPR8, ISPF_RHOE4 ;  C1BAC3, ISPF_RHOOB ;  A3PJQ4, ISPF_RHOS1 ;
DR   Q3J2K8, ISPF_RHOS4 ;  A4WSL4, ISPF_RHOS5 ;  B9KSH9, ISPF_RHOSK ;
DR   Q0S889, ISPF_RHOSR ;  Q165P5, ISPF_ROSDO ;  Q1AU09, ISPF_RUBXD ;
DR   Q21LB9, ISPF_SACD2 ;  B5F410, ISPF_SALA4 ;  A8M7S7, ISPF_SALAI ;
DR   A9MF29, ISPF_SALAR ;  Q57KJ5, ISPF_SALCH ;  B5FTS4, ISPF_SALDC ;
DR   B5QW17, ISPF_SALEP ;  B5RDQ2, ISPF_SALG2 ;  B4TFW6, ISPF_SALHS ;
DR   B4T456, ISPF_SALNS ;  Q5PEG2, ISPF_SALPA ;  A9N2D2, ISPF_SALPB ;
DR   C0PXA6, ISPF_SALPC ;  B5BEY3, ISPF_SALPK ;  Q2S211, ISPF_SALRD ;
DR   B4TTW0, ISPF_SALSV ;  Q8Z472, ISPF_SALTI ;  A4XCN1, ISPF_SALTO ;
DR   Q8ZMF7, ISPF_SALTY ;  A8G9Z3, ISPF_SERP5 ;  A1S4E0, ISPF_SHEAM ;
DR   B8E8T4, ISPF_SHEB2 ;  A3D792, ISPF_SHEB5 ;  A6WR25, ISPF_SHEB8 ;
DR   A9KYG7, ISPF_SHEB9 ;  Q12PZ1, ISPF_SHEDO ;  Q086A7, ISPF_SHEFN ;
DR   B0TK07, ISPF_SHEHH ;  A3QC80, ISPF_SHELP ;  Q8EBR3, ISPF_SHEON ;
DR   A8H1S8, ISPF_SHEPA ;  A4Y940, ISPF_SHEPC ;  B8CJP9, ISPF_SHEPW ;
DR   A0KU85, ISPF_SHESA ;  A8FST1, ISPF_SHESH ;  Q0HL69, ISPF_SHESM ;
DR   Q0HXG7, ISPF_SHESR ;  A1RHF6, ISPF_SHESW ;  B1KPT3, ISPF_SHEWM ;
DR   B2TZI5, ISPF_SHIB3 ;  Q31XA8, ISPF_SHIBS ;  Q32CI4, ISPF_SHIDS ;
DR   Q0T1H7, ISPF_SHIF8 ;  P62619, ISPF_SHIFL ;  Q3YYB6, ISPF_SHISS ;
DR   Q2NVM3, ISPF_SODGM ;  Q027G2, ISPF_SOLUE ;  Q82GC9, ISPF_STRAW ;
DR   Q9L0Q7, ISPF_STRCO ;  B1VS88, ISPF_STRGG ;  Q67JP6, ISPF_SYMTH ;
DR   Q2LUT1, ISPF_SYNAS ;  Q31P19, ISPF_SYNE7 ;  A0LIS1, ISPF_SYNFM ;
DR   Q2JXJ4, ISPF_SYNJA ;  Q2JNA9, ISPF_SYNJB ;  Q5N549, ISPF_SYNP6 ;
DR   Q0IC27, ISPF_SYNS3 ;  Q0AUF5, ISPF_SYNWW ;  P73426, ISPF_SYNY3 ;
DR   Q8DHC4, ISPF_THEEB ;  Q47KT3, ISPF_THEFY ;  Q9WZB5, ISPF_THEMA ;
DR   B9KAZ0, ISPF_THENN ;  Q72HP8, ISPF_THET2 ;  Q8RQP5, ISPF_THET8 ;
DR   Q8R7S8, ISPF_THETN ;  Q3SK37, ISPF_THIDA ;  B8GQ78, ISPF_THISH ;
DR   Q73KC6, ISPF_TREDE ;  B1GYT3, ISPF_UNCTG ;  A1WR07, ISPF_VEREI ;
DR   A5F9D7, ISPF_VIBC3 ;  Q9KUJ1, ISPF_VIBCH ;  C3LS19, ISPF_VIBCM ;
DR   Q5E329, ISPF_VIBF1 ;  B5FAF6, ISPF_VIBFM ;  A7MTS5, ISPF_VIBHB ;
DR   Q87LQ3, ISPF_VIBPA ;  Q8DC59, ISPF_VIBVU ;  Q7MHQ5, ISPF_VIBVY ;
DR   Q8D224, ISPF_WIGBR ;  Q8PLR7, ISPF_XANAC ;  Q3BUS7, ISPF_XANC5 ;
DR   Q4UTP5, ISPF_XANC8 ;  B0RU02, ISPF_XANCB ;  Q8P9Z0, ISPF_XANCP ;
DR   Q2P1L1, ISPF_XANOM ;  B2SUA9, ISPF_XANOP ;  Q5GYK7, ISPF_XANOR ;
DR   Q9PDT5, ISPF_XYLFA ;  Q87DY3, ISPF_XYLFT ;  A1JJT5, ISPF_YERE8 ;
DR   A7FLX7, ISPF_YERP3 ;  Q1C477, ISPF_YERPA ;  B2K578, ISPF_YERPB ;
DR   Q8ZBP7, ISPF_YERPE ;  A9R118, ISPF_YERPG ;  Q1CLR5, ISPF_YERPN ;
DR   A4TPZ8, ISPF_YERPP ;  Q66EC2, ISPF_YERPS ;  B1JJF7, ISPF_YERPY ;
//
ID   4.6.1.13
DE   Phosphatidylinositol diacylglycerol-lyase.
AN   1-phosphatidylinositol phosphodiesterase.
AN   Monophosphatidylinositol phosphodiesterase.
AN   Phosphatidylinositol phospholipase C.
CA   1-phosphatidyl-1D-myo-inositol = 1D-myo-inositol 1,2-cyclic phosphate +
CA   1,2-diacyl-sn-glycerol.
CC   -!- This enzyme is bacterial.
CC   -!- Activity is also found in animals, but this activity is due to the
CC       presence of EC 3.1.4.11.
CC   -!- Formerly EC 3.1.4.10.
DR   P14262, PLC_BACCE  ;  P08954, PLC_BACTU  ;  P34024, PLC_LISMO  ;
DR   P45723, PLC_STAAE  ;
//
ID   4.6.1.14
DE   Glycosylphosphatidylinositol diacylglycerol-lyase.
AN   (Glycosyl)phosphatidylinositol-specific phospholipase C.
AN   6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol diacylglycerol-
AN   lyase (1,2-cyclic-phosphate-forming).
AN   Glycosyl inositol phospholipid anchor-hydrolyzing enzyme.
AN   Glycosylphosphatidylinositol-phospholipase C.
AN   Glycosylphosphatidylinositol-specific phospholipase C.
AN   GPI-PLC.
AN   GPI-specific phospholipase C.
AN   Variant-surface-glycoprotein phospholipase C.
AN   VSG-lipase.
CA   6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol = 6-(alpha-D-
CA   glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate + 1,2-diacyl-
CA   sn-glycerol.
CC   -!- This enzyme is also active when O-4 of the glucosamine is substituted
CC       by carrying the oligosaccharide that can link a protein to the
CC       structure.
CC   -!- It therefore cleaves proteins from the lipid part of the
CC       glycosylphostphatidylinositol (GPI) anchors.
CC   -!- In some cases, the long-chain acyl group at the sn-1 position of
CC       glycerol is replaced by an alkyl or alk-1-enyl group.
CC   -!- In other cases, the diacylglycerol is replaced by ceramide.
CC   -!- The only characterized enzyme with this specificity is from
CC       Trypanosoma brucei, where the acyl groups are myristoyl, but the
CC       function of the trypanosome enzyme is unknown.
CC   -!- Substitution on O-2 of the inositol blocks action of this enzyme.
CC   -!- It is not identical with EC 3.1.4.50.
CC   -!- Formerly EC 3.1.4.47.
DR   P09194, PHLC_TRYBB ;  O15886, PHLC_TRYCR ;
//
ID   4.6.1.15
DE   FAD-AMP lyase (cyclizing).
AN   FMN cyclase.
CA   FAD = AMP + riboflavin cyclic-4',5'-phosphate.
CF   Manganese or cobalt.
CC   -!- While FAD was the best substrate tested the enzyme also splits
CC       ribonucleoside diphosphate-X compounds in which X is an acyclic or
CC       cyclic monosaccharide or derivative bearing an X-OH group that is
CC       able to attack internally the proximal phosphorus with the geometry
CC       necessary to form a P=X product; either a five-atom monocyclic
CC       phosphodiester or a cis-bicyclic phosphodiester-pyranose fusion.
CC   -!- The reaction is strongly inhibited by ADP or ATP but is unaffected by
CC       the presence of the product, cFMN.
DR   Q58DK4, DHAK_BOVIN ;  Q3LXA3, DHAK_HUMAN ;  Q8VC30, DHAK_MOUSE ;
DR   Q4KLZ6, DHAK_RAT   ;
//
ID   4.99.1.1
DE   Ferrochelatase.
AN   Heme synthase.
AN   Heme synthetase.
AN   Iron chelatase.
AN   Protoheme ferro-lyase.
CA   Protoheme + 2 H(+) = protoporphyrin + Fe(2+).
PR   PROSITE; PDOC00462;
DR   P42043, HEMH1_ARATH;  Q81U22, HEMH1_BACAN;  Q73C98, HEMH1_BACC1;
DR   Q81GW5, HEMH1_BACCR;  Q63ES4, HEMH1_BACCZ;  Q6HM97, HEMH1_BACHK;
DR   Q69TB1, HEMH1_ORYSJ;  Q8EFF4, HEMH1_SHEON;  O04921, HEMH2_ARATH;
DR   Q81TU9, HEMH2_BACAN;  Q73C08, HEMH2_BACC1;  Q81GN7, HEMH2_BACCR;
DR   Q63EK7, HEMH2_BACCZ;  Q6HM28, HEMH2_BACHK;  Q0DIV0, HEMH2_ORYSJ;
DR   Q8EBZ7, HEMH2_SHEON;  Q6F7N0, HEMH_ACIAD ;  B7H0X1, HEMH_ACIB3 ;
DR   B7I4A8, HEMH_ACIB5 ;  B2I2R9, HEMH_ACIBC ;  B0VLE0, HEMH_ACIBS ;
DR   A3M1P7, HEMH_ACIBT ;  B0VEC9, HEMH_ACIBY ;  C1F1C7, HEMH_ACIC5 ;
DR   A3N3M9, HEMH_ACTP2 ;  B3H307, HEMH_ACTP7 ;  B0BTL7, HEMH_ACTPJ ;
DR   A0KL51, HEMH_AERHH ;  Q8U9F7, HEMH_AGRT5 ;  B9JS40, HEMH_AGRVS ;
DR   Q0VSV6, HEMH_ALCBS ;  B6EHK1, HEMH_ALISL ;  B4S1G4, HEMH_ALTMD ;
DR   Q3MCT9, HEMH_ANAVT ;  B7GF12, HEMH_ANOFW ;  O67083, HEMH_AQUAE ;
DR   Q5P1H1, HEMH_AROAE ;  A1K8P4, HEMH_AZOSB ;  C1DEU1, HEMH_AZOVD ;
DR   Q9KDK9, HEMH_BACHD ;  A8FBM6, HEMH_BACP2 ;  Q5WHT1, HEMH_BACSK ;
DR   P32396, HEMH_BACSU ;  A9VI99, HEMH_BACWK ;  Q6MHT3, HEMH_BDEBA ;
DR   Q7WGI0, HEMH_BORBR ;  Q7W515, HEMH_BORPA ;  Q7VVX8, HEMH_BORPE ;
DR   P22600, HEMH_BOVIN ;  P28602, HEMH_BRAJA ;  A5EBP8, HEMH_BRASB ;
DR   B2SCP3, HEMH_BRUA1 ;  Q2YIS9, HEMH_BRUA2 ;  P0A3D8, HEMH_BRUAB ;
DR   A9MDJ3, HEMH_BRUC2 ;  C0RK28, HEMH_BRUMB ;  P0A3D6, HEMH_BRUME ;
DR   A5VTJ7, HEMH_BRUO2 ;  A9WXE2, HEMH_BRUSI ;  P0A3D7, HEMH_BRUSU ;
DR   B1YTJ5, HEMH_BURA4 ;  Q1BYX9, HEMH_BURCA ;  B1JW14, HEMH_BURCC ;
DR   A0K4S2, HEMH_BURCH ;  Q0BI24, HEMH_BURCM ;  A3MNA4, HEMH_BURM7 ;
DR   A2S570, HEMH_BURM9 ;  Q62HD1, HEMH_BURMA ;  A1V0U1, HEMH_BURMS ;
DR   A3NYY2, HEMH_BURP0 ;  Q3JP06, HEMH_BURP1 ;  A3ND73, HEMH_BURP6 ;
DR   B2JGE7, HEMH_BURP8 ;  B2SXB8, HEMH_BURPP ;  Q63R43, HEMH_BURPS ;
DR   Q39JD2, HEMH_BURS3 ;  Q2SYZ9, HEMH_BURTA ;  A4JBR6, HEMH_BURVG ;
DR   Q145F5, HEMH_BURXL ;  A7ZE60, HEMH_CAMC1 ;  A0RNU4, HEMH_CAMFF ;
DR   A8FKS9, HEMH_CAMJ8 ;  A7H4N6, HEMH_CAMJD ;  Q9PI08, HEMH_CAMJE ;
DR   A1VYL5, HEMH_CAMJJ ;  Q5HVR0, HEMH_CAMJR ;  B8GW40, HEMH_CAUCN ;
DR   P57777, HEMH_CAUCR ;  O42479, HEMH_CHICK ;  Q5L6X6, HEMH_CHLAB ;
DR   Q824K8, HEMH_CHLCV ;  Q252Z7, HEMH_CHLFF ;  Q9PJQ6, HEMH_CHLMU ;
DR   Q9Z7V1, HEMH_CHLPN ;  B0B858, HEMH_CHLT2 ;  Q3KLL2, HEMH_CHLTA ;
DR   B0BCC3, HEMH_CHLTB ;  O84492, HEMH_CHLTR ;  Q7NV65, HEMH_CHRVO ;
DR   Q6NH66, HEMH_CORDI ;  Q8FTB1, HEMH_COREF ;  A4QEC1, HEMH_CORGB ;
DR   Q8NQA1, HEMH_CORGL ;  B6J5R6, HEMH_COXB1 ;  B6J386, HEMH_COXB2 ;
DR   A9KGX9, HEMH_COXBN ;  Q83FA4, HEMH_COXBU ;  P42044, HEMH_CUCSA ;
DR   Q0KCJ6, HEMH_CUPNH ;  Q473L7, HEMH_CUPPJ ;  B3R447, HEMH_CUPTR ;
DR   B8HK77, HEMH_CYAP4 ;  B7KGB9, HEMH_CYAP7 ;  B7K399, HEMH_CYAP8 ;
DR   Q47HJ6, HEMH_DECAR ;  Q9RV98, HEMH_DEIRA ;  Q6APB0, HEMH_DESPS ;
DR   Q54IA8, HEMH_DICDI ;  Q9V9S8, HEMH_DROME ;  A7ZIN5, HEMH_ECO24 ;
DR   B7UKF5, HEMH_ECO27 ;  B7MDZ7, HEMH_ECO45 ;  B7L7A0, HEMH_ECO55 ;
DR   Q8XD39, HEMH_ECO57 ;  B5Z3Y6, HEMH_ECO5E ;  B7NIF5, HEMH_ECO7I ;
DR   B7MQJ0, HEMH_ECO81 ;  B7M3W7, HEMH_ECO8A ;  C4ZUS9, HEMH_ECOBW ;
DR   B1XFR2, HEMH_ECODH ;  A7ZXD3, HEMH_ECOHS ;  A1A8E1, HEMH_ECOK1 ;
DR   Q0TKG6, HEMH_ECOL5 ;  Q8FK83, HEMH_ECOL6 ;  B1IZB9, HEMH_ECOLC ;
DR   P23871, HEMH_ECOLI ;  B7N928, HEMH_ECOLU ;  B6I0C7, HEMH_ECOSE ;
DR   B1LJN3, HEMH_ECOSM ;  Q1RF60, HEMH_ECOUT ;  C5BD17, HEMH_EDWI9 ;
DR   A4W7F9, HEMH_ENT38 ;  Q833G5, HEMH_ENTFA ;  A7MNM8, HEMH_ENTS8 ;
DR   Q6D7Z4, HEMH_ERWCT ;  B2VHX1, HEMH_ERWT9 ;  B7LV14, HEMH_ESCF3 ;
DR   Q0RH75, HEMH_FRAAA ;  Q14H85, HEMH_FRAT1 ;  A7NBJ3, HEMH_FRATF ;
DR   Q2A406, HEMH_FRATH ;  B2SDE2, HEMH_FRATM ;  A0Q6Z1, HEMH_FRATN ;
DR   Q0BME1, HEMH_FRATO ;  Q5NFT3, HEMH_FRATT ;  A4IYH5, HEMH_FRATW ;
DR   B5EJ44, HEMH_GEOBB ;  Q5L283, HEMH_GEOKA ;  Q39ZQ5, HEMH_GEOMG ;
DR   B9M326, HEMH_GEOSF ;  Q747F5, HEMH_GEOSL ;  C6E7U2, HEMH_GEOSM ;
DR   C5D6M6, HEMH_GEOSW ;  A4IKU8, HEMH_GEOTN ;  A5GDG7, HEMH_GEOUR ;
DR   Q7NMC7, HEMH_GLOVI ;  Q5FSJ9, HEMH_GLUOX ;  Q4QLD6, HEMH_HAEI8 ;
DR   A5UCU6, HEMH_HAEIE ;  P43868, HEMH_HAEIN ;  C4K332, HEMH_HAMD5 ;
DR   Q17YG0, HEMH_HELAH ;  Q7VHH1, HEMH_HELHP ;  B6JMR9, HEMH_HELP2 ;
DR   B5Z875, HEMH_HELPG ;  Q1CSI9, HEMH_HELPH ;  Q9ZKD4, HEMH_HELPJ ;
DR   B2UUI4, HEMH_HELPS ;  P56107, HEMH_HELPY ;  A9B546, HEMH_HERA2 ;
DR   A4G8D5, HEMH_HERAR ;  P42045, HEMH_HORVU ;  P22830, HEMH_HUMAN ;
DR   Q0BWA5, HEMH_HYPNA ;  Q5QVZ8, HEMH_IDILO ;  A6T228, HEMH_JANMA ;
DR   B5Y0N2, HEMH_KLEP3 ;  Q036X3, HEMH_LACC3 ;  B3W963, HEMH_LACCB ;
DR   Q9CFB4, HEMH_LACLA ;  A2RJS3, HEMH_LACLM ;  Q02Y14, HEMH_LACLS ;
DR   Q88XC3, HEMH_LACPL ;  A5VLS3, HEMH_LACRD ;  B2G944, HEMH_LACRJ ;
DR   Q5X7W3, HEMH_LEGPA ;  A5IHG9, HEMH_LEGPC ;  Q5ZYE7, HEMH_LEGPH ;
DR   Q5WZB4, HEMH_LEGPL ;  Q6AHF2, HEMH_LEIXX ;  B0SF60, HEMH_LEPBA ;
DR   Q8GCV0, HEMH_LEPBI ;  Q04NU7, HEMH_LEPBJ ;  Q04X34, HEMH_LEPBL ;
DR   B0SNJ9, HEMH_LEPBP ;  Q03Z41, HEMH_LEUMM ;  Q929G2, HEMH_LISIN ;
DR   Q71XF4, HEMH_LISMF ;  Q8Y565, HEMH_LISMO ;  Q65SV7, HEMH_MANSM ;
DR   A1U0R2, HEMH_MARAV ;  A6VXF8, HEMH_MARMS ;  Q11ES4, HEMH_MESSB ;
DR   Q607T4, HEMH_METCA ;  Q1H397, HEMH_METFK ;  A2SIR1, HEMH_METPP ;
DR   B8EJ84, HEMH_METSB ;  B0JRN7, HEMH_MICAN ;  P22315, HEMH_MOUSE ;
DR   A0QHT7, HEMH_MYCA1 ;  B1MC29, HEMH_MYCA9 ;  O07401, HEMH_MYCAV ;
DR   P0A577, HEMH_MYCBO ;  A1KIS5, HEMH_MYCBP ;  C1AND1, HEMH_MYCBT ;
DR   A4T9I1, HEMH_MYCGI ;  B8ZS79, HEMH_MYCLB ;  Q9CBM2, HEMH_MYCLE ;
DR   B2HPD6, HEMH_MYCMM ;  Q740Y1, HEMH_MYCPA ;  A0QX29, HEMH_MYCS2 ;
DR   A3PZF2, HEMH_MYCSJ ;  A1UFU2, HEMH_MYCSK ;  Q1B968, HEMH_MYCSS ;
DR   A5U2I9, HEMH_MYCTA ;  P0A576, HEMH_MYCTU ;  A0PNU6, HEMH_MYCUA ;
DR   A1T8R1, HEMH_MYCVP ;  Q5F9U6, HEMH_NEIG1 ;  Q9JVA5, HEMH_NEIMA ;
DR   Q9K097, HEMH_NEIMB ;  A1KSY0, HEMH_NEIMF ;  Q82UK8, HEMH_NITEU ;
DR   Q1QI02, HEMH_NITHX ;  Q3JAW7, HEMH_NITOC ;  A6Q2Y9, HEMH_NITSB ;
DR   Q5YU18, HEMH_NOCFA ;  B2J9P0, HEMH_NOSP7 ;  Q8YQR8, HEMH_NOSS1 ;
DR   Q8ERX9, HEMH_OCEIH ;  A6X6W2, HEMH_OCHA4 ;  B1ZSW3, HEMH_OPITP ;
DR   A2Y3Q5, HEMH_ORYSI ;  Q3YA36, HEMH_PANTR ;  Q6MAW8, HEMH_PARUW ;
DR   P57874, HEMH_PASMU ;  A1ASJ7, HEMH_PELPD ;  Q4FNS1, HEMH_PELUB ;
DR   B4RD10, HEMH_PHEZH ;  Q7N0P6, HEMH_PHOLL ;  Q6LTE0, HEMH_PHOPR ;
DR   Q12BZ9, HEMH_POLSJ ;  B2RHB4, HEMH_PORG3 ;  Q7MXP4, HEMH_PORGI ;
DR   P72183, HEMH_PROFF ;  A3PBP9, HEMH_PROM0 ;  A2C0Y4, HEMH_PROM1 ;
DR   A8G3P0, HEMH_PROM2 ;  A2C7Q7, HEMH_PROM3 ;  A9BEE9, HEMH_PROM4 ;
DR   A2BVI7, HEMH_PROM5 ;  Q31C09, HEMH_PROM9 ;  Q7VD58, HEMH_PROMA ;
DR   B4F1Q1, HEMH_PROMH ;  Q7V6C6, HEMH_PROMM ;  Q7V2F5, HEMH_PROMP ;
DR   A2BQ06, HEMH_PROMS ;  Q46GQ1, HEMH_PROMT ;  Q48MT5, HEMH_PSE14 ;
DR   Q15NQ1, HEMH_PSEA6 ;  A6VC51, HEMH_PSEA7 ;  B7V0K1, HEMH_PSEA8 ;
DR   Q02G19, HEMH_PSEAB ;  Q9HVD7, HEMH_PSEAE ;  Q1IEW1, HEMH_PSEE4 ;
DR   Q4K6B3, HEMH_PSEF5 ;  P57778, HEMH_PSEFC ;  C3KDN7, HEMH_PSEFS ;
DR   A4XR78, HEMH_PSEMY ;  A5VYH6, HEMH_PSEP1 ;  Q3K6Y7, HEMH_PSEPF ;
DR   B0KNF5, HEMH_PSEPG ;  Q88PV4, HEMH_PSEPK ;  B1JER5, HEMH_PSEPW ;
DR   Q888A2, HEMH_PSESM ;  Q4ZXU9, HEMH_PSEU2 ;  A4VKZ1, HEMH_PSEU5 ;
DR   Q4FUR3, HEMH_PSYA2 ;  Q1QDQ5, HEMH_PSYCK ;  A5WH56, HEMH_PSYWF ;
DR   Q1LPN9, HEMH_RALME ;  B2UBQ0, HEMH_RALPJ ;  Q8XW32, HEMH_RALSO ;
DR   B3PZU8, HEMH_RHIE6 ;  Q2K4C4, HEMH_RHIEC ;  Q1MBW8, HEMH_RHIL3 ;
DR   Q98H61, HEMH_RHILO ;  B5ZPG3, HEMH_RHILW ;  Q92M52, HEMH_RHIME ;
DR   Q7UFZ7, HEMH_RHOBA ;  Q59735, HEMH_RHOCA ;  Q2IRD5, HEMH_RHOP2 ;
DR   Q07H58, HEMH_RHOP5 ;  Q6NBF3, HEMH_RHOPA ;  Q13CU0, HEMH_RHOPS ;
DR   B3QF66, HEMH_RHOPT ;  A8GYD7, HEMH_RICB8 ;  Q1RGK5, HEMH_RICBR ;
DR   A8F0B2, HEMH_RICCK ;  Q92FV4, HEMH_RICCN ;  Q4UJN9, HEMH_RICFE ;
DR   Q9ZC84, HEMH_RICPR ;  Q68VM9, HEMH_RICTY ;  B5EXN2, HEMH_SALA4 ;
DR   A9MLY4, HEMH_SALAR ;  Q57S74, HEMH_SALCH ;  B5FLJ9, HEMH_SALDC ;
DR   B5QU78, HEMH_SALEP ;  B5R613, HEMH_SALG2 ;  B4T9I3, HEMH_SALHS ;
DR   B4SWY3, HEMH_SALNS ;  Q5PFJ1, HEMH_SALPA ;  A9MW82, HEMH_SALPB ;
DR   C0PVE1, HEMH_SALPC ;  B5BD43, HEMH_SALPK ;  B4TMG7, HEMH_SALSV ;
DR   Q8Z8T2, HEMH_SALTI ;  P37408, HEMH_SALTY ;  O59786, HEMH_SCHPO ;
DR   A8GAV7, HEMH_SERP5 ;  Q12KR9, HEMH_SHEDO ;  B2U4S8, HEMH_SHIB3 ;
DR   Q325C1, HEMH_SHIBS ;  Q32J55, HEMH_SHIDS ;  Q0T7B0, HEMH_SHIF8 ;
DR   Q83SE5, HEMH_SHIFL ;  Q3Z4S4, HEMH_SHISS ;  Q2NV56, HEMH_SODGM ;
DR   Q5HEU3, HEMH_STAAC ;  P64124, HEMH_STAAM ;  P64125, HEMH_STAAN ;
DR   Q6GFM4, HEMH_STAAR ;  Q6G8A3, HEMH_STAAS ;  P64126, HEMH_STAAW ;
DR   Q5HNA5, HEMH_STAEQ ;  Q8CNS1, HEMH_STAES ;  Q49YM6, HEMH_STAS1 ;
DR   Q82KJ6, HEMH_STRAW ;  O50533, HEMH_STRCO ;  B1VXN6, HEMH_STRGG ;
DR   B4SNS0, HEMH_STRM5 ;  Q8CWW4, HEMH_STRMU ;  Q04KS4, HEMH_STRP2 ;
DR   C1C6Y5, HEMH_STRP7 ;  B1IBG8, HEMH_STRPI ;  B8ZPG2, HEMH_STRPJ ;
DR   Q97R30, HEMH_STRPN ;  B2IPG3, HEMH_STRPS ;  Q8DQ04, HEMH_STRR6 ;
DR   C1CE03, HEMH_STRZJ ;  C1CRD1, HEMH_STRZT ;  Q30S35, HEMH_SULDN ;
DR   B2V955, HEMH_SULSY ;  Q67T48, HEMH_SYMTH ;  Q31S00, HEMH_SYNE7 ;
DR   Q2JVK5, HEMH_SYNJA ;  Q2JHZ4, HEMH_SYNJB ;  B1XL79, HEMH_SYNP2 ;
DR   Q5N2B2, HEMH_SYNP6 ;  A5GJF5, HEMH_SYNPW ;  Q7U5G0, HEMH_SYNPX ;
DR   A5GS98, HEMH_SYNR3 ;  Q0I8L9, HEMH_SYNS3 ;  Q3ALP2, HEMH_SYNSC ;
DR   P54225, HEMH_SYNY3 ;  C5BIF4, HEMH_TERTT ;  Q9HLB8, HEMH_THEAC ;
DR   Q8DGU6, HEMH_THEEB ;  Q72L32, HEMH_THET2 ;  Q978U9, HEMH_THEVO ;
DR   Q31EG9, HEMH_THICR ;  Q3SHA3, HEMH_THIDA ;  B8GU82, HEMH_THISH ;
DR   Q10WR6, HEMH_TRIEI ;  Q83H94, HEMH_TROW8 ;  Q83FJ2, HEMH_TROWT ;
DR   Q9KTB6, HEMH_VIBCH ;  Q5E6Q7, HEMH_VIBF1 ;  B5FBZ6, HEMH_VIBFM ;
DR   Q87RH3, HEMH_VIBPA ;  B7VII4, HEMH_VIBSL ;  Q8DFM2, HEMH_VIBVU ;
DR   Q7MMR4, HEMH_VIBVY ;  Q8D226, HEMH_WIGBR ;  Q73FY6, HEMH_WOLPM ;
DR   B3CLU1, HEMH_WOLPP ;  Q7M7P9, HEMH_WOLSU ;  Q5GRR7, HEMH_WOLTR ;
DR   C0R4L0, HEMH_WOLWR ;  Q8PEX0, HEMH_XANAC ;  Q8P3H6, HEMH_XANCP ;
DR   O57478, HEMH_XENLA ;  B2I7H7, HEMH_XYLF2 ;  Q9PFU1, HEMH_XYLFA ;
DR   B0U456, HEMH_XYLFM ;  Q87B82, HEMH_XYLFT ;  P16622, HEMH_YEAST ;
DR   A1JNA4, HEMH_YERE8 ;  P43413, HEMH_YEREN ;  A7FL85, HEMH_YERP3 ;
DR   Q1C4Q0, HEMH_YERPA ;  B2K6Z7, HEMH_YERPB ;  Q8ZC98, HEMH_YERPE ;
DR   A9R0Q8, HEMH_YERPG ;  Q1CL26, HEMH_YERPN ;  A4TPA3, HEMH_YERPP ;
DR   Q05338, HEMH_YERPS ;  B1JHN0, HEMH_YERPY ;  P57779, HEMH_ZYMMO ;
//
ID   4.99.1.2
DE   Alkylmercury lyase.
AN   Organomercurial lyase.
AN   Organomercury lyase.
CA   An alkylmercury + H(+) = an alkane + Hg(2+).
CC   -!- Acts on CH(3)Hg(+) and a number of other alkylmercury compounds,
CC       in the presence of cysteine or other thiols, liberating mercury as a
CC       mercaptide.
CC   -!- Some arylmercury compounds can also act as substrates.
DR   P16172, MERB_BACCE ;  P62224, MERB_CLOBU ;  P77072, MERB_ECOLX ;
DR   P62225, MERB_KLEPN ;  Q8G9P0, MERB_PSEPU ;  Q91UN2, MERB_RHIME ;
DR   P08664, MERB_SERMA ;  P08653, MERB_STAAU ;  Q8CU52, MERB_STAES ;
DR   P30342, MERB_STRLI ;
//
ID   4.99.1.3
DE   Sirohydrochlorin cobaltochelatase.
AN   Anaerobic cobalt chelatase.
AN   Cobaltochelatase.
CA   Cobalt-sirohydrochlorin + 2 H(+) = sirohydrochlorin + Co(2+).
CC   -!- This enzyme is a type II chelatase, being either a monomer (CbiX) or
CC       a homodimer (CibK) and being ATP-independent.
CC   -!- CbiK from Salmonella enterica uses precorrin-2 as the substrate to
CC       yield cobalt-precorrin-2.
CC   -!- The enzyme contains two histidines at the active site that are
CC       thought to be involved in the deprotonation of the tetrapyrrole
CC       substrate as well as in metal binding.
CC   -!- CbiX from Bacillus megaterium inserts cobalt at the level of
CC       sirohydrochlorin (factor-II) rather than precorrin-2.
DR   Q72CB8, CBIKC_DESVH;  Q72EC8, CBIKP_DESVH;  Q05592, CBIK_SALTY ;
DR   O29537, CBIX_ARCFU ;  O87690, CBIX_BACME ;  Q9HQM3, CBIX_HALSA ;
DR   A6UWT5, CBIX_META3 ;  Q8TJZ5, CBIX_METAC ;  P61816, CBIX_METBF ;
DR   Q12X56, CBIX_METBU ;  Q58380, CBIX_METJA ;  Q8TY77, CBIX_METKA ;
DR   Q8PZH6, CBIX_METMA ;  P61819, CBIX_METMP ;  O27448, CBIX_METTH ;
DR   Q4JAI2, CBIX_SULAC ;  C3MZ53, CBIX_SULIA ;  C4KID1, CBIX_SULIK ;
DR   C3MR05, CBIX_SULIL ;  C3MWZ3, CBIX_SULIM ;  C3NGG2, CBIX_SULIN ;
DR   C3N773, CBIX_SULIY ;  Q980A7, CBIX_SULSO ;  Q975N6, CBIX_SULTO ;
DR   Q55451, CBIX_SYNY3 ;
//
ID   4.99.1.4
DE   Sirohydrochlorin ferrochelatase.
CA   Siroheme + 2 H(+) = sirohydrochlorin + Fe(2+).
CC   -!- This enzyme catalyzes the third of three steps leading to the
CC       formation of siroheme from uroporphyrinogen III.
CC   -!- The first step involves the donation of two S-adenosyl-L-methionine-
CC       derived methyl groups to carbons 2 and 7 of uroporphyrinogen III to
CC       form precorrin-2 (EC 2.1.1.107) and the second step involves an
CC       NAD(+)-dependent dehydrogenation to form sirohydrochlorin from
CC       precorrin-2 (EC 1.3.1.76).
CC   -!- In Saccharomyces cerevisiae, the last two steps are carried out by a
CC       single bifunctional enzyme, Met8p.
CC   -!- In some bacteria, steps 1-3 are catalyzed by a single multifunctional
CC       protein called CysG, whereas in Bacillus megaterium, three separate
CC       enzymes carry out each of the steps, with SirB being responsible for
CC       the above reaction.
DR   Q72CB8, CBIKC_DESVH;  Q72EC8, CBIKP_DESVH;  A0KLD7, CYSG1_AERHH;
DR   A4SHL4, CYSG1_AERS4;  A7MJ67, CYSG1_ENTS8;  Q6D1A4, CYSG1_ERWCT;
DR   A1WWP8, CYSG1_HALHL;  A6TD45, CYSG1_KLEP7;  A8G9Y3, CYSG1_SERP5;
DR   A1JJS8, CYSG1_YERE8;  A7FLY4, CYSG1_YERP3;  Q1CLS2, CYSG1_YERPN;
DR   A4TGU8, CYSG1_YERPP;  Q66EC9, CYSG1_YERPS;  A0KP37, CYSG2_AERHH;
DR   A4SRH0, CYSG2_AERS4;  A7MKK9, CYSG2_ENTS8;  Q6CZS0, CYSG2_ERWCT;
DR   A1WYD5, CYSG2_HALHL;  A6TF07, CYSG2_KLEP7;  A8GKQ1, CYSG2_SERP5;
DR   A1JSB7, CYSG2_YERE8;  A7FNS9, CYSG2_YERP3;  Q1CCP6, CYSG2_YERPN;
DR   A4TPZ1, CYSG2_YERPP;  Q664M6, CYSG2_YERPS;  A0KQJ4, CYSG3_AERHH;
DR   Q6F8G6, CYSG_ACIAD ;  B3GZA0, CYSG_ACTP7 ;  B0BTC2, CYSG_ACTPJ ;
DR   A6VPZ6, CYSG_ACTSZ ;  Q0VQ05, CYSG_ALCBS ;  Q0A812, CYSG_ALHEH ;
DR   C1DKY7, CYSG_AZOVD ;  Q1LTP4, CYSG_BAUCH ;  Q7VQG9, CYSG_BLOFL ;
DR   Q493N1, CYSG_BLOPB ;  Q2KWB0, CYSG_BORA1 ;  Q7WMM4, CYSG_BORBR ;
DR   Q7WB57, CYSG_BORPA ;  A9HZV6, CYSG_BORPD ;  Q7VZ77, CYSG_BORPE ;
DR   P57500, CYSG_BUCAI ;  Q7NZV7, CYSG_CHRVO ;  A8AQS4, CYSG_CITK8 ;
DR   A7ZSP4, CYSG_ECO24 ;  B7UK79, CYSG_ECO27 ;  B7MCY5, CYSG_ECO45 ;
DR   B7L4P2, CYSG_ECO55 ;  P0AEA9, CYSG_ECO57 ;  B5YTS6, CYSG_ECO5E ;
DR   B7NMD7, CYSG_ECO7I ;  B7N1F1, CYSG_ECO81 ;  B7M1S1, CYSG_ECO8A ;
DR   C4ZUM4, CYSG_ECOBW ;  B1X716, CYSG_ECODH ;  A8A5H5, CYSG_ECOHS ;
DR   A1AGQ2, CYSG_ECOK1 ;  Q0TC92, CYSG_ECOL5 ;  Q8FCW8, CYSG_ECOL6 ;
DR   B1IP96, CYSG_ECOLC ;  P0AEA8, CYSG_ECOLI ;  B7NDX8, CYSG_ECOLU ;
DR   B6I2S7, CYSG_ECOSE ;  B1LHG9, CYSG_ECOSM ;  Q1R5R3, CYSG_ECOUT ;
DR   C5BGP8, CYSG_EDWI9 ;  A4WFH1, CYSG_ENT38 ;  B7LS75, CYSG_ESCF3 ;
DR   A9H259, CYSG_GLUDA ;  Q5FP95, CYSG_GLUOX ;  Q2SJB7, CYSG_HAHCH ;
DR   Q65T49, CYSG_MANSM ;  Q606C9, CYSG_METCA ;  Q1H3L5, CYSG_METFK ;
DR   A9LZ77, CYSG_NEIM0 ;  P57001, CYSG_NEIMA ;  P95370, CYSG_NEIMB ;
DR   A1KU10, CYSG_NEIMF ;  Q0AHC1, CYSG_NITEC ;  Q820Q4, CYSG_NITEU ;
DR   Q2Y6L7, CYSG_NITMU ;  Q3JCS0, CYSG_NITOC ;  Q7N8L2, CYSG_PHOLL ;
DR   Q6LM67, CYSG_PHOPR ;  Q48H75, CYSG_PSE14 ;  Q15YU1, CYSG_PSEA6 ;
DR   A6V4H6, CYSG_PSEA7 ;  B7UW11, CYSG_PSEA8 ;  Q02NA3, CYSG_PSEAB ;
DR   Q9I0M7, CYSG_PSEAE ;  Q1IBC9, CYSG_PSEE4 ;  Q4K9V8, CYSG_PSEF5 ;
DR   C3JY53, CYSG_PSEFS ;  Q3ILQ9, CYSG_PSEHT ;  A4XUX3, CYSG_PSEMY ;
DR   A5W1H7, CYSG_PSEP1 ;  Q3KA85, CYSG_PSEPF ;  Q88FT3, CYSG_PSEPK ;
DR   B1JBD9, CYSG_PSEPW ;  Q87ZT0, CYSG_PSESM ;  Q4ZRL6, CYSG_PSEU2 ;
DR   A4VLU6, CYSG_PSEU5 ;  Q4FSU1, CYSG_PSYA2 ;  Q1QAX7, CYSG_PSYCK ;
DR   A1SRP9, CYSG_PSYIN ;  A5WEG6, CYSG_PSYWF ;  A1AVU5, CYSG_RUTMC ;
DR   Q21K21, CYSG_SACD2 ;  B5F8J0, CYSG_SALA4 ;  A9MME5, CYSG_SALAR ;
DR   Q57IZ5, CYSG_SALCH ;  B5FJQ1, CYSG_SALDC ;  B5R2C7, CYSG_SALEP ;
DR   B5R7N6, CYSG_SALG2 ;  B4TKQ4, CYSG_SALHS ;  B4SVI1, CYSG_SALNS ;
DR   Q5PLV8, CYSG_SALPA ;  A9MT45, CYSG_SALPB ;  C0Q0F3, CYSG_SALPC ;
DR   B5BH22, CYSG_SALPK ;  B4TY38, CYSG_SALSV ;  Q8Z201, CYSG_SALTI ;
DR   P25924, CYSG_SALTY ;  B2U3H4, CYSG_SHIB3 ;  Q31VS0, CYSG_SHIBS ;
DR   Q32AZ8, CYSG_SHIDS ;  Q0SZU8, CYSG_SHIF8 ;  Q83JB3, CYSG_SHIFL ;
DR   Q3YWQ3, CYSG_SHISS ;  Q2NVN0, CYSG_SODGM ;  Q31GG8, CYSG_THICR ;
DR   Q3SG32, CYSG_THIDA ;  B8GUD3, CYSG_THISH ;  C4LAG5, CYSG_TOLAT ;
DR   A5CXE4, CYSG_VESOH ;  B2I985, CYSG_XYLF2 ;  Q9PF46, CYSG_XYLFA ;
DR   B0U4X0, CYSG_XYLFM ;  Q87AI5, CYSG_XYLFT ;  Q1C2P9, CYSG_YERPA ;
DR   Q74Y23, CYSG_YERPE ;  Q5NRM4, CYSG_ZYMMO ;  O14172, MET8_SCHPO ;
DR   P15807, MET8_YEAST ;  P61817, SIRB_BACME ;  O34632, SIRB_BACSU ;
//
ID   4.99.1.5
DE   Aliphatic aldoxime dehydratase.
CA   An aliphatic aldoxime = an aliphatic nitrile + H(2)O.
CF   Calcium; Protoheme IX.
CC   -!- Exhibits a strong preference for aliphatic aldoximes, such as
CC       butyraldoxime and acetaldoxime, over aromatic aldoximes, such as
CC       pyridine-2-aldoxime, which is a poor substrate.
CC   -!- No activity was found with the aromatic aldoximes benzaldoxime and
CC       pyridine-4-aldoxime.
//
ID   4.99.1.6
DE   Indoleacetaldoxime dehydratase.
AN   3-indoleacetaldoxime hydro-lyase.
AN   Indole-3-acetaldehyde-oxime hydro-lyase.
AN   Indoleacetaldoxime hydro-lyase.
CA   (Indol-3-yl)acetaldehyde oxime = (indol-3-yl)acetonitrile + H(2)O.
CC   -!- Formerly EC 4.2.1.29.
DR   O49342, C71AD_ARATH;
//
ID   4.99.1.7
DE   Phenylacetaldoxime dehydratase.
AN   Arylacetaldoxime dehydratase.
AN   PAOx dehydratase.
CA   (Z)-phenylacetaldehyde oxime = phenylacetonitrile + H(2)O.
CF   Heme.
CC   -!- The enzyme from Bacillus sp. OxB-1 contains protoheme IX, the iron of
CC       which must be in the form Fe(2+) for activity.
CC   -!- (Z)-phenylacetaldoxime binds to ferric heme (the Fe(3+) form) via the
CC       oxygen atom whereas it binds to the active ferrous form via the
CC       nitrogen atom.
CC   -!- In this way, the oxidation state of the heme controls the
CC       coordination stucture of the substrate--heme complex, which regulates
CC       enzyme activity.
CC   -!- The enzyme is active toward several (Z)-arylacetaldoximes and (E/Z)-
CC       alkylaldoximes as well as toward arylalkylaldoximes such as
CC       3-phenylpropionaldoxime and 4-phenylbutyraldoxime.
CC   -!- However, it is inactive with phenylacetaldoximes that have a
CC       substituent group at an alpha-site of an oxime group, for example,
CC       with (E/Z)-2-phenylpropionaldoxime and (E/Z)-mandelaldoxime.
CC   -!- The activity of the enzyme is inhibited completely by the heavy-metal
CC       cations Cu(+), Cu(2+), Ag(+) and Hg(+) whereas Fe(2+) and Sn(2+) have
CC       an activatory effect.
DR   P82604, OXD_BACSX  ;
//
ID   4.99.1.8
DE   Heme ligase.
AN   Hemozoin synthase.
CA   2 ferriprotoporphyrin IX = beta-hematin.
CC   -!- This heme detoxifying enzyme is found in Plasmodium parasites and
CC       converts toxic heme to crystalline hemozoin.
CC   -!- These organisms lack the mammalian heme oxygenase for elimination of
CC       heme.
//
ID   5.1.1.1
DE   Alanine racemase.
CA   L-alanine = D-alanine.
CF   Pyridoxal 5'-phosphate.
PR   PROSITE; PDOC00332;
DR   P58736, ALR1_AGRT5 ;  P10725, ALR1_BACSU ;  Q97LR2, ALR1_CLOAB ;
DR   Q8X5V2, ALR1_ECO57 ;  Q8FB20, ALR1_ECOL6 ;  P0A6B4, ALR1_ECOLI ;
DR   Q8ELR9, ALR1_OCEIH ;  Q9HUN4, ALR1_PSEAE ;  Q98A05, ALR1_RHILO ;
DR   P0A1A4, ALR1_SALTI ;  P0A1A3, ALR1_SALTY ;  O59828, ALR1_SCHPO ;
DR   P0A6B6, ALR1_SHIBO ;  Q932V0, ALR1_SHIDY ;  P0A6B5, ALR1_SHIFL ;
DR   Q93HP9, ALR1_SHISO ;  Q9ZAH5, ALR1_STAA8 ;  Q5HED1, ALR1_STAAC ;
DR   P63479, ALR1_STAAM ;  P63480, ALR1_STAAN ;  Q6GF03, ALR1_STAAR ;
DR   Q6G7N9, ALR1_STAAS ;  P63481, ALR1_STAAW ;  Q8RAK6, ALR1_THETN ;
DR   Q9KUY6, ALR1_VIBCH ;  Q87L78, ALR1_VIBPA ;  Q8DCL0, ALR1_VIBVU ;
DR   Q8ZJ10, ALR1_YERPE ;  P58737, ALR2_AGRT5 ;  P94494, ALR2_BACSU ;
DR   Q97DY9, ALR2_CLOAB ;  Q8X4I9, ALR2_ECO57 ;  P59237, ALR2_ECOL6 ;
DR   P29012, ALR2_ECOLI ;  O30746, ALR2_ENTAE ;  Q8ELK1, ALR2_OCEIH ;
DR   Q9HTQ2, ALR2_PSEAE ;  Q9RAE7, ALR2_RHIL3 ;  Q98F05, ALR2_RHILO ;
DR   Q8Z688, ALR2_SALTI ;  P06191, ALR2_SALTY ;  Q9P5N3, ALR2_SCHPO ;
DR   Q9EZ08, ALR2_STAA8 ;  Q5HG21, ALR2_STAAC ;  P63482, ALR2_STAAM ;
DR   P63483, ALR2_STAAN ;  Q8R860, ALR2_THETN ;  Q9KSE5, ALR2_VIBCH ;
DR   Q87HG4, ALR2_VIBPA ;  Q8D6Q0, ALR2_VIBVU ;  Q8ZFL4, ALR2_YERPE ;
DR   Q981H7, ALR3_RHILO ;  Q8Z300, ALR3_SALTI ;  A1TIS2, ALR_ACIAC  ;
DR   B0VNF6, ALR_ACIBS  ;  A5G2H9, ALR_ACICJ  ;  B9MAN2, ALR_ACIET  ;
DR   B7J911, ALR_ACIF2  ;  B5EP95, ALR_ACIF5  ;  A1W2F6, ALR_ACISJ  ;
DR   A3MYX4, ALR_ACTP2  ;  A6VP88, ALR_ACTSZ  ;  Q0VMG4, ALR_ALCBS  ;
DR   B6ELK6, ALR_ALISL  ;  B4S1A6, ALR_ALTMD  ;  B7GFP5, ALR_ANOFW  ;
DR   O67687, ALR_AQUAE  ;  Q9RER4, ALR_AQUPY  ;  A8ESX7, ALR_ARCB4  ;
DR   Q5P3K0, ALR_AROAE  ;  A1KCI5, ALR_AZOSB  ;  Q9KFF9, ALR_BACHD  ;
DR   Q9S5V6, ALR_BACPS  ;  C5BZY7, ALR_BEUC1  ;  Q2KXU7, ALR_BORA1  ;
DR   O51182, ALR_BORBU  ;  B7J192, ALR_BORBZ  ;  A9IU63, ALR_BORPD  ;
DR   Q2YIU9, ALR_BRUA2  ;  A9MCK3, ALR_BRUC2  ;  Q8YD03, ALR_BRUME  ;
DR   A5VVI9, ALR_BRUO2  ;  A9WVT5, ALR_BRUSI  ;  Q8FVC1, ALR_BRUSU  ;
DR   A3MKW5, ALR_BURM7  ;  A2SB51, ALR_BURM9  ;  Q62JA4, ALR_BURMA  ;
DR   A1V591, ALR_BURMS  ;  B2T5L6, ALR_BURPP  ;  A7ZCL1, ALR_CAMC1  ;
DR   A7GZM8, ALR_CAMC5  ;  A8FLV4, ALR_CAMJ8  ;  A7H3E3, ALR_CAMJD  ;
DR   Q9PP26, ALR_CAMJE  ;  A1VZN9, ALR_CAMJJ  ;  Q5HUQ3, ALR_CAMJR  ;
DR   Q9F8I0, ALR_CARHZ  ;  Q9A7Q9, ALR_CAUCR  ;  Q8KB67, ALR_CHLTE  ;
DR   Q1QU82, ALR_CHRSD  ;  A5N376, ALR_CLOK5  ;  A0PY95, ALR_CLONN  ;
DR   Q0TSS9, ALR_CLOP1  ;  Q8XM22, ALR_CLOPE  ;  Q0SUN0, ALR_CLOPS  ;
DR   Q890X1, ALR_CLOTE  ;  B5Y9T8, ALR_COPPD  ;  Q8FS13, ALR_COREF  ;
DR   A4QBT0, ALR_CORGB  ;  Q8RSU9, ALR_CORGL  ;  B6J6U2, ALR_COXB1  ;
DR   B6J0J1, ALR_COXB2  ;  A9KFM0, ALR_COXBN  ;  A9ND48, ALR_COXBR  ;
DR   Q83D71, ALR_COXBU  ;  Q0K9V9, ALR_CUPNH  ;  B3R2F9, ALR_CUPTR  ;
DR   C1CVP5, ALR_DEIDV  ;  Q1IYK9, ALR_DEIGD  ;  Q9RVE3, ALR_DEIRA  ;
DR   A9BR02, ALR_DELAS  ;  B8J2K3, ALR_DESDA  ;  A8ZRV0, ALR_DESOH  ;
DR   A4J8G6, ALR_DESRM  ;  Q72DH4, ALR_DESVH  ;  B8DRL1, ALR_DESVM  ;
DR   A1VF31, ALR_DESVV  ;  A5EW54, ALR_DICNV  ;  A8LRT3, ALR_DINSH  ;
DR   C5BCC5, ALR_EDWI9  ;  Q3V7N2, ALR_ERWCT  ;  B2VJ52, ALR_ERWT9  ;
DR   B0TYB0, ALR_FRAP2  ;  Q2JFD6, ALR_FRASC  ;  Q14IP6, ALR_FRAT1  ;
DR   A7ND36, ALR_FRATF  ;  Q2A2P9, ALR_FRATH  ;  B2SHB9, ALR_FRATM  ;
DR   A0Q5X2, ALR_FRATN  ;  Q0BL88, ALR_FRATO  ;  Q5NH94, ALR_FRATT  ;
DR   A4IZ25, ALR_FRATW  ;  Q8RGA2, ALR_FUSNN  ;  B5EBG2, ALR_GEOBB  ;
DR   Q5L3G4, ALR_GEOKA  ;  Q39RJ8, ALR_GEOMG  ;  P10724, ALR_GEOSE  ;
DR   Q74FK2, ALR_GEOSL  ;  C6E5Z6, ALR_GEOSM  ;  Q7VNC9, ALR_HAEDU  ;
DR   P45257, ALR_HAEIN  ;  Q2SLB1, ALR_HAHCH  ;  A1WUS2, ALR_HALHL  ;
DR   B8D0W1, ALR_HALOH  ;  C4K4C4, ALR_HAMD5  ;  Q17WC4, ALR_HELAH  ;
DR   B6JMG2, ALR_HELP2  ;  B5Z7U5, ALR_HELPG  ;  Q1CST1, ALR_HELPH  ;
DR   Q9ZKQ9, ALR_HELPJ  ;  B2UU89, ALR_HELPS  ;  O25595, ALR_HELPY  ;
DR   A6SY68, ALR_JANMA  ;  Q28RK6, ALR_JANSC  ;  Q5FMB2, ALR_LACAC  ;
DR   Q03T06, ALR_LACBA  ;  Q034T9, ALR_LACC3  ;  B3WAR0, ALR_LACCB  ;
DR   Q1GBP6, ALR_LACDA  ;  Q04C45, ALR_LACDB  ;  B2GA65, ALR_LACF3  ;
DR   Q046E7, ALR_LACGA  ;  A8YXI3, ALR_LACH4  ;  Q9CH94, ALR_LACLA  ;
DR   Q9RLU5, ALR_LACLM  ;  Q030B4, ALR_LACLS  ;  O08445, ALR_LACPL  ;
DR   A5VI51, ALR_LACRD  ;  Q9FCV2, ALR_LACRE  ;  B2G5M9, ALR_LACRJ  ;
DR   Q1WV14, ALR_LACS1  ;  Q38V64, ALR_LACSS  ;  C1DBE8, ALR_LARHH  ;
DR   Q1MSD5, ALR_LAWIP  ;  Q5X709, ALR_LEGPA  ;  A5IGG9, ALR_LEGPC  ;
DR   Q5ZXJ2, ALR_LEGPH  ;  Q5WYG1, ALR_LEGPL  ;  B1Y2H6, ALR_LEPCP  ;
DR   Q75FF2, ALR_LEPIC  ;  Q8EX97, ALR_LEPIN  ;  Q92DC9, ALR_LISIN  ;
DR   C1L1F6, ALR_LISMC  ;  Q721S9, ALR_LISMF  ;  B8DG73, ALR_LISMH  ;
DR   O85045, ALR_LISMO  ;  A0AH04, ALR_LISW6  ;  B9E8C3, ALR_MACCJ  ;
DR   Q65TC1, ALR_MANSM  ;  A1U388, ALR_MARAV  ;  A6W1F2, ALR_MARMS  ;
DR   Q607M5, ALR_METCA  ;  Q1H1N8, ALR_METFK  ;  B3DWZ0, ALR_METI4  ;
DR   B8IEC7, ALR_METNO  ;  A2SLS6, ALR_METPP  ;  B0UL34, ALR_METS4  ;
DR   A0QKR9, ALR_MYCA1  ;  Q9L888, ALR_MYCAV  ;  P0A4X3, ALR_MYCBO  ;
DR   P38056, ALR_MYCLE  ;  A0QSR6, ALR_MYCS2  ;  P94967, ALR_MYCSM  ;
DR   P0A4X2, ALR_MYCTU  ;  A0PME2, ALR_MYCUA  ;  A1T566, ALR_MYCVP  ;
DR   Q5F788, ALR_NEIG1  ;  Q9JTA6, ALR_NEIMA  ;  Q9JYC4, ALR_NEIMB  ;
DR   A1KV59, ALR_NEIMF  ;  Q0AFV7, ALR_NITEC  ;  Q82UR4, ALR_NITEU  ;
DR   Q2Y763, ALR_NITMU  ;  Q3JEJ2, ALR_NITOC  ;  A6Q1W0, ALR_NITSB  ;
DR   Q8YU96, ALR_NOSS1  ;  Q9CNL5, ALR_PASMU  ;  C6DE79, ALR_PECCP  ;
DR   Q03DZ2, ALR_PEDPA  ;  A5D4I1, ALR_PELTS  ;  P83944, ALR_PENMO  ;
DR   Q3V7I5, ALR_PHOPR  ;  Q9F9L1, ALR_PISSA  ;  A1VIH8, ALR_POLNA  ;
DR   Q12H34, ALR_POLSJ  ;  Q6A5H2, ALR_PROAC  ;  Q7V9Z2, ALR_PROMA  ;
DR   Q48PY9, ALR_PSE14  ;  Q15NL4, ALR_PSEA6  ;  Q1I2V7, ALR_PSEE4  ;
DR   Q4K3T9, ALR_PSEF5  ;  P33162, ALR_PSEFL  ;  Q4ZZW2, ALR_PSEU2  ;
DR   A4VQM5, ALR_PSEU5  ;  A5WDJ3, ALR_PSYWF  ;  Q1LNJ3, ALR_RALME  ;
DR   B2UAX2, ALR_RALPJ  ;  Q8XZM4, ALR_RALSO  ;  Q92R07, ALR_RHIME  ;
DR   Q221R3, ALR_RHOFD  ;  Q2RXD1, ALR_RHORT  ;  A3PIR7, ALR_RHOS1  ;
DR   Q3J3L4, ALR_RHOS4  ;  A4WRF5, ALR_RHOS5  ;  B9KQC8, ALR_RHOSK  ;
DR   C3PMD1, ALR_RICAE  ;  A8GM54, ALR_RICAH  ;  Q1RGU4, ALR_RICBR  ;
DR   A8EXF8, ALR_RICCK  ;  Q92JD9, ALR_RICCN  ;  Q4UNC8, ALR_RICFE  ;
DR   Q9ZE52, ALR_RICPR  ;  C4K1B0, ALR_RICPU  ;  B0BW55, ALR_RICRO  ;
DR   A8GQR1, ALR_RICRS  ;  Q68XW3, ALR_RICTY  ;  Q163V1, ALR_ROSDO  ;
DR   A8M4B3, ALR_SALAI  ;  A4XBI0, ALR_SALTO  ;  A1SA53, ALR_SHEAM  ;
DR   B8E9P2, ALR_SHEB2  ;  A3D8P9, ALR_SHEB5  ;  A6WJ85, ALR_SHEB8  ;
DR   A9L126, ALR_SHEB9  ;  Q12RW2, ALR_SHEDO  ;  Q07XT3, ALR_SHEFN  ;
DR   A3QI45, ALR_SHELP  ;  Q8EAI6, ALR_SHEON  ;  A8H8K6, ALR_SHEPA  ;
DR   A4Y3F6, ALR_SHEPC  ;  B8CIQ9, ALR_SHEPW  ;  A0KT33, ALR_SHESA  ;
DR   A8FRA1, ALR_SHESH  ;  Q0HF52, ALR_SHESM  ;  Q0HYW0, ALR_SHESR  ;
DR   A1RNI3, ALR_SHESW  ;  B1KHY4, ALR_SHEWM  ;  B2TX62, ALR_SHIB3  ;
DR   Q31TW1, ALR_SHIBS  ;  Q327W0, ALR_SHIDS  ;  Q1GFQ4, ALR_SILST  ;
DR   Q2NTA8, ALR_SODGM  ;  A9ESU7, ALR_SORC5  ;  Q2FF55, ALR_STAA3  ;
DR   A6QIR5, ALR_STAAE  ;  B9DMI9, ALR_STACT  ;  Q5HME5, ALR_STAEQ  ;
DR   Q8CNK7, ALR_STAES  ;  Q49Z24, ALR_STAS1  ;  Q3JZK5, ALR_STRA1  ;
DR   Q8E3M9, ALR_STRA3  ;  Q8DY10, ALR_STRA5  ;  O86786, ALR_STRCO  ;
DR   C0M6I5, ALR_STRE4  ;  B4U178, ALR_STREM  ;  A8AVC4, ALR_STRGC  ;
DR   Q8DSF4, ALR_STRMU  ;  Q99Y98, ALR_STRP1  ;  Q04J74, ALR_STRP2  ;
DR   P0CZ56, ALR_STRP3  ;  B5E745, ALR_STRP4  ;  Q5XAA4, ALR_STRP6  ;
DR   C1C8T6, ALR_STRP7  ;  Q8NZK4, ALR_STRP8  ;  Q1JA50, ALR_STRPB  ;
DR   Q1JKA0, ALR_STRPC  ;  Q1JF94, ALR_STRPD  ;  Q1J545, ALR_STRPF  ;
DR   A2RCT3, ALR_STRPG  ;  B1I755, ALR_STRPI  ;  B8ZMG1, ALR_STRPJ  ;
DR   Q48RM8, ALR_STRPM  ;  P0A2W8, ALR_STRPN  ;  P0CZ57, ALR_STRPQ  ;
DR   B5XI21, ALR_STRPZ  ;  P0A2W9, ALR_STRR6  ;  A4W3N5, ALR_STRS2  ;
DR   C0MEB7, ALR_STRS7  ;  A4VXD9, ALR_STRSY  ;  Q5LY71, ALR_STRT1  ;
DR   Q5M2S7, ALR_STRT2  ;  Q03IX8, ALR_STRTD  ;  B9DVI3, ALR_STRU0  ;
DR   C1CFR7, ALR_STRZJ  ;  C1CM34, ALR_STRZP  ;  C1CSV9, ALR_STRZT  ;
DR   A6QC54, ALR_SULNB  ;  Q67K79, ALR_SYMTH  ;  A0LFQ9, ALR_SYNFM  ;
DR   P54918, ALR_SYNY3  ;  Q47LN3, ALR_THEFY  ;  B5YIM9, ALR_THEYD  ;
DR   Q3SH36, ALR_THIDA  ;  B8GNS7, ALR_THISH  ;  Q73NQ7, ALR_TREDE  ;
DR   Q56346, ALR_TREPA  ;  B2S3S0, ALR_TREPS  ;  C5CX88, ALR_VARPS  ;
DR   A1WQY3, ALR_VEREI  ;  A5CWE3, ALR_VESOH  ;  B7VI70, ALR_VIBSL  ;
DR   Q7MH94, ALR_VIBVY  ;  Q8D2H8, ALR_WIGBR  ;  Q8PGD0, ALR_XANAC  ;
DR   Q3BNX4, ALR_XANC5  ;  Q4UQB5, ALR_XANC8  ;  Q8P4R0, ALR_XANCP  ;
DR   Q2P7U1, ALR_XANOM  ;  Q5H522, ALR_XANOR  ;  Q9PF26, ALR_XYLFA  ;
DR   Q87AK1, ALR_XYLFT  ;  A9QYT2, ALR_YERPG  ;  Q9UW18, TOXG_COCCA ;
DR   Q9X3P3, VANT_ENTGA ;
//
ID   5.1.1.2
DE   Methionine racemase.
CA   L-methionine = D-methionine.
CF   Pyridoxal 5'-phosphate.
//
ID   5.1.1.3
DE   Glutamate racemase.
CA   L-glutamate = D-glutamate.
CF   Pyridoxal 5'-phosphate.
PR   PROSITE; PDOC00714;
DR   O68006, BACA_BACLI ;  P94556, MURI1_BACSU;  Q8RD38, MURI1_THETN;
DR   O05412, MURI2_BACSU;  Q8RC52, MURI2_THETN;  Q8RAJ0, MURI3_THETN;
DR   Q1INP0, MURI_ACIBL ;  A0LVJ8, MURI_ACIC1 ;  A3N3D7, MURI_ACTP2 ;
DR   B3GZ94, MURI_ACTP7 ;  B0BT16, MURI_ACTPJ ;  Q8UE93, MURI_AGRT5 ;
DR   B6ENT1, MURI_ALISL ;  Q3MD46, MURI_ANAVT ;  O66662, MURI_AQUAE ;
DR   P56868, MURI_AQUPY ;  A8ERI7, MURI_ARCB4 ;  A7Z7C8, MURI_BACA2 ;
DR   O31332, MURI_BACC1 ;  B7IIZ3, MURI_BACC2 ;  C1ETT1, MURI_BACC3 ;
DR   B7HEB5, MURI_BACC4 ;  Q633V2, MURI_BACCZ ;  A8FFY8, MURI_BACP2 ;
DR   Q5WEL9, MURI_BACSK ;  A1UT12, MURI_BARBK ;  Q6G3D5, MURI_BARHE ;
DR   Q6FZU3, MURI_BARQU ;  A9IU96, MURI_BART1 ;  C5BY82, MURI_BEUC1 ;
DR   B8DT03, MURI_BIFA0 ;  A1A2L6, MURI_BIFAA ;  B3DQ51, MURI_BIFLD ;
DR   Q8G7Z8, MURI_BIFLO ;  B7GPZ1, MURI_BIFLS ;  O51127, MURI_BORBU ;
DR   B2S641, MURI_BRUA1 ;  Q2YRV4, MURI_BRUA2 ;  Q57CU6, MURI_BRUAB ;
DR   A9M5L1, MURI_BRUC2 ;  C0RJG2, MURI_BRUMB ;  P63631, MURI_BRUME ;
DR   A5VQW7, MURI_BRUO2 ;  B0CGZ3, MURI_BRUSI ;  P63632, MURI_BRUSU ;
DR   B8D9X6, MURI_BUCA5 ;  P57619, MURI_BUCAI ;  Q8K924, MURI_BUCAP ;
DR   B8D878, MURI_BUCAT ;  P59574, MURI_BUCBP ;  A7ZDH6, MURI_CAMC1 ;
DR   A7GYL9, MURI_CAMC5 ;  A0RNJ6, MURI_CAMFF ;  Q9PM24, MURI_CAMJE ;
DR   Q3AFA8, MURI_CARHZ ;  Q9L4V5, MURI_CARST ;  B0T549, MURI_CAUSK ;
DR   B3QQD9, MURI_CHLP8 ;  A1BDJ6, MURI_CHLPD ;  Q8KFN8, MURI_CHLTE ;
DR   Q97E66, MURI_CLOAB ;  A7FZC4, MURI_CLOB1 ;  C3KWB8, MURI_CLOB6 ;
DR   B2UX89, MURI_CLOBA ;  B2THT3, MURI_CLOBB ;  A5I7T7, MURI_CLOBH ;
DR   C1FNG8, MURI_CLOBJ ;  B1IH18, MURI_CLOBK ;  A7GJF6, MURI_CLOBL ;
DR   B1KTG4, MURI_CLOBM ;  B9DY32, MURI_CLOK1 ;  A5N4H0, MURI_CLOK5 ;
DR   A0Q3B8, MURI_CLONN ;  Q0TM83, MURI_CLOP1 ;  Q8XHB7, MURI_CLOPE ;
DR   Q0SPY8, MURI_CLOPS ;  Q6NFN4, MURI_CORDI ;  Q8FMU6, MURI_COREF ;
DR   Q9XDZ7, MURI_CORGL ;  C4LJY7, MURI_CORK4 ;  Q46Z37, MURI_CUPPJ ;
DR   B7KCC4, MURI_CYAP7 ;  B7JWN0, MURI_CYAP8 ;  Q9RU10, MURI_DEIRA ;
DR   B1I4X2, MURI_DESAP ;  A8LMF7, MURI_DINSH ;  A7ZUI7, MURI_ECO24 ;
DR   B7MIA7, MURI_ECO45 ;  B7LA65, MURI_ECO55 ;  P63633, MURI_ECO57 ;
DR   B7NU33, MURI_ECO7I ;  B7MR95, MURI_ECO81 ;  B7M723, MURI_ECO8A ;
DR   C5A0R6, MURI_ECOBW ;  B1XBX8, MURI_ECODH ;  A8A775, MURI_ECOHS ;
DR   Q8FB89, MURI_ECOL6 ;  P22634, MURI_ECOLI ;  B6I5I5, MURI_ECOSE ;
DR   Q1R3U0, MURI_ECOUT ;  Q836J0, MURI_ENTFA ;  Q6CZB6, MURI_ERWCT ;
DR   B2VGA6, MURI_ERWT9 ;  B7LUM6, MURI_ESCF3 ;  C4Z114, MURI_EUBE2 ;
DR   B1YJW7, MURI_EXIS2 ;  A8L764, MURI_FRASN ;  Q8REE6, MURI_FUSNN ;
DR   Q5KWI3, MURI_GEOKA ;  Q39Y84, MURI_GEOMG ;  C5D5M9, MURI_GEOSW ;
DR   Q7NKI2, MURI_GLOVI ;  Q0BTT2, MURI_GRABC ;  Q7VKJ3, MURI_HAEDU ;
DR   Q4QJK7, MURI_HAEI8 ;  A5UBE2, MURI_HAEIE ;  A5UFH0, MURI_HAEIG ;
DR   P52973, MURI_HAEIN ;  B8F7R8, MURI_HAEPS ;  Q0I5M2, MURI_HAES1 ;
DR   B0URZ3, MURI_HAES2 ;  B8D151, MURI_HALOH ;  Q17XG8, MURI_HELAH ;
DR   B6JLD2, MURI_HELP2 ;  B5Z6S2, MURI_HELPG ;  Q1CTX8, MURI_HELPH ;
DR   Q9ZLT0, MURI_HELPJ ;  B2UTT1, MURI_HELPS ;  P56068, MURI_HELPY ;
DR   A9AXC6, MURI_HERA2 ;  B4UA20, MURI_HYDS0 ;  Q28PV7, MURI_JANSC ;
DR   B5XZ09, MURI_KLEP3 ;  Q5FLV8, MURI_LACAC ;  Q03R52, MURI_LACBA ;
DR   P48797, MURI_LACBR ;  B2GB35, MURI_LACF3 ;  Q03469, MURI_LACFE ;
DR   A8YTR6, MURI_LACH4 ;  Q74KU5, MURI_LACJO ;  Q9CG28, MURI_LACLA ;
DR   A2RKH0, MURI_LACLM ;  Q02YQ3, MURI_LACLS ;  Q88V19, MURI_LACPL ;
DR   A5VIY5, MURI_LACRD ;  B2G6G1, MURI_LACRJ ;  Q38YM1, MURI_LACSS ;
DR   Q6AEK8, MURI_LEIXX ;  Q04QQ5, MURI_LEPBJ ;  Q053X4, MURI_LEPBL ;
DR   Q72TI2, MURI_LEPIC ;  Q8F1S7, MURI_LEPIN ;  Q92CH2, MURI_LISIN ;
DR   C1L2E2, MURI_LISMC ;  Q720J2, MURI_LISMF ;  B8DHZ5, MURI_LISMH ;
DR   Q8Y7N7, MURI_LISMO ;  A0AHX8, MURI_LISW6 ;  B1HW77, MURI_LYSSC ;
DR   P52972, MURI_LYSSH ;  A6VX99, MURI_MARMS ;  Q609F9, MURI_METCA ;
DR   B0JGW5, MURI_MICAN ;  A0QD02, MURI_MYCA1 ;  P63636, MURI_MYCBO ;
DR   A1KIC8, MURI_MYCBP ;  C1AMY3, MURI_MYCBT ;  B8ZR57, MURI_MYCLB ;
DR   P46705, MURI_MYCLE ;  B2HQH3, MURI_MYCMM ;  Q73X85, MURI_MYCPA ;
DR   A0R1X0, MURI_MYCS2 ;  A5U238, MURI_MYCTA ;  P63635, MURI_MYCTU ;
DR   A0PUH6, MURI_MYCUA ;  Q5F6P9, MURI_NEIG1 ;  P0A0Q9, MURI_NEIMA ;
DR   P0A0R0, MURI_NEIMB ;  Q9RMM3, MURI_NEIMC ;  A1KVG8, MURI_NEIMF ;
DR   A6Q504, MURI_NITSB ;  Q9L870, MURI_NOSS1 ;  Q8EPJ4, MURI_OCEIH ;
DR   A6X0F8, MURI_OCHA4 ;  Q04G05, MURI_OENOB ;  A1B945, MURI_PARDP ;
DR   P57887, MURI_PASMU ;  C6DHQ3, MURI_PECCP ;  Q03ES4, MURI_PEDPA ;
DR   Q08783, MURI_PEDPE ;  C0QQ35, MURI_PERMH ;  B4RCD6, MURI_PHEZH ;
DR   Q7MYE4, MURI_PHOLL ;  B4S417, MURI_PROA2 ;  A2C175, MURI_PROM1 ;
DR   B4F1H6, MURI_PROMH ;  Q46LT2, MURI_PROMT ;  A6VC58, MURI_PSEA7 ;
DR   B7V0K8, MURI_PSEA8 ;  Q02G12, MURI_PSEAB ;  Q9HVD0, MURI_PSEAE ;
DR   Q1IEW8, MURI_PSEE4 ;  A4XR64, MURI_PSEMY ;  A5VYG8, MURI_PSEP1 ;
DR   B0KNE7, MURI_PSEPG ;  Q88PW2, MURI_PSEPK ;  B1JEP3, MURI_PSEPW ;
DR   Q888B8, MURI_PSESM ;  A4VPB6, MURI_PSEU5 ;  B2U6V5, MURI_RALPJ ;
DR   Q8XY07, MURI_RALSO ;  Q98NP9, MURI_RHILO ;  Q92PG8, MURI_RHIME ;
DR   C3MD87, MURI_RHISN ;  A3PK37, MURI_RHOS1 ;  Q3J276, MURI_RHOS4 ;
DR   A4WQY6, MURI_RHOS5 ;  Q163W3, MURI_ROSDO ;  A5UTG1, MURI_ROSS1 ;
DR   A4F910, MURI_SACEN ;  Q57H86, MURI_SALCH ;  B5QXR2, MURI_SALEP ;
DR   B5REZ1, MURI_SALG2 ;  Q5PK79, MURI_SALPA ;  B5BJP1, MURI_SALPK ;
DR   Q8Z315, MURI_SALTI ;  P40723, MURI_SALTY ;  A8GL72, MURI_SERP5 ;
DR   B8EBM4, MURI_SHEB2 ;  A3DA79, MURI_SHEB5 ;  A6WHQ9, MURI_SHEB8 ;
DR   A9KW83, MURI_SHEB9 ;  Q12SP7, MURI_SHEDO ;  Q089S6, MURI_SHEFN ;
DR   B0TMV5, MURI_SHEHH ;  A3Q963, MURI_SHELP ;  Q8EK90, MURI_SHEON ;
DR   A8GYV7, MURI_SHEPA ;  B8CH57, MURI_SHEPW ;  A0KRK5, MURI_SHESA ;
DR   Q0HNV7, MURI_SHESM ;  Q0I0C5, MURI_SHESR ;  B1KN02, MURI_SHEWM ;
DR   Q0SY24, MURI_SHIF8 ;  P63634, MURI_SHIFL ;  Q5LS93, MURI_SILPO ;
DR   Q1GHL1, MURI_SILST ;  A6U9N0, MURI_SINMW ;  Q2NQZ7, MURI_SODGM ;
DR   Q1GTU9, MURI_SPHAL ;  A7X179, MURI_STAA1 ;  A6U0W7, MURI_STAA2 ;
DR   Q2FHT1, MURI_STAA3 ;  Q2FZC6, MURI_STAA8 ;  A5IS36, MURI_STAA9 ;
DR   Q2YXC5, MURI_STAAB ;  Q5HGT3, MURI_STAAC ;  A6QG53, MURI_STAAE ;
DR   P63637, MURI_STAAM ;  P63638, MURI_STAAN ;  Q6GHT5, MURI_STAAR ;
DR   Q6GA64, MURI_STAAS ;  A8Z1T2, MURI_STAAT ;  P63639, MURI_STAAW ;
DR   B9DPT7, MURI_STACT ;  Q5HQ24, MURI_STAEQ ;  Q8CPL0, MURI_STAES ;
DR   P52974, MURI_STAHA ;  Q4L5F5, MURI_STAHJ ;  Q49WR7, MURI_STAS1 ;
DR   Q3JZT5, MURI_STRA1 ;  Q8E3V7, MURI_STRA3 ;  Q8DY92, MURI_STRA5 ;
DR   C0M7R0, MURI_STRE4 ;  A8AYU3, MURI_STRGC ;  Q8DSQ5, MURI_STRMU ;
DR   Q9A1B7, MURI_STRP1 ;  Q04IS7, MURI_STRP2 ;  P0CZ88, MURI_STRP3 ;
DR   B5E1Z3, MURI_STRP4 ;  Q5XDP9, MURI_STRP6 ;  C1C9E7, MURI_STRP7 ;
DR   Q8P2D3, MURI_STRP8 ;  Q1JDD6, MURI_STRPB ;  Q1JNA9, MURI_STRPC ;
DR   Q1JIG0, MURI_STRPD ;  Q1J8B4, MURI_STRPF ;  A2RG97, MURI_STRPG ;
DR   B1I891, MURI_STRPI ;  B8ZNI5, MURI_STRPJ ;  Q48V50, MURI_STRPM ;
DR   P63640, MURI_STRPN ;  P0CZ89, MURI_STRPQ ;  B2ISX9, MURI_STRPS ;
DR   B5XJX3, MURI_STRPZ ;  P63641, MURI_STRR6 ;  A4W3D7, MURI_STRS2 ;
DR   C0MGG5, MURI_STRS7 ;  A3CPR2, MURI_STRSV ;  A4VX33, MURI_STRSY ;
DR   Q5M1I5, MURI_STRT1 ;  Q5M627, MURI_STRT2 ;  Q03MG1, MURI_STRTD ;
DR   B9DTR9, MURI_STRU0 ;  C1CGA5, MURI_STRZJ ;  C1CMJ1, MURI_STRZP ;
DR   C1CTB1, MURI_STRZT ;  A6QBL4, MURI_SULNB ;  B2V9I5, MURI_SULSY ;
DR   Q67SL6, MURI_SYMTH ;  Q2LXZ9, MURI_SYNAS ;  B1XPV8, MURI_SYNP2 ;
DR   Q3AKJ1, MURI_SYNSC ;  P73737, MURI_SYNY3 ;  B0KBP8, MURI_THEP3 ;
DR   B0K3R0, MURI_THEPX ;  Q72I52, MURI_THET2 ;  Q5SHT7, MURI_THET8 ;
DR   O83421, MURI_TREPA ;  B2S303, MURI_TREPS ;  Q11A19, MURI_TRIEI ;
DR   A5F4P4, MURI_VIBC3 ;  Q9KVI7, MURI_VIBCH ;  C3LPZ8, MURI_VIBCM ;
DR   Q5E218, MURI_VIBF1 ;  B5FCA3, MURI_VIBFM ;  A7MXD3, MURI_VIBHB ;
DR   Q87KP1, MURI_VIBPA ;  Q8DD39, MURI_VIBVU ;  Q7MQ40, MURI_VIBVY ;
DR   Q8D368, MURI_WIGBR ;  A1JI42, MURI_YERE8 ;  A7FD15, MURI_YERP3 ;
DR   B2JZF9, MURI_YERPB ;  Q8ZAA2, MURI_YERPE ;  Q66G56, MURI_YERPS ;
DR   B1JQ44, MURI_YERPY ;
//
ID   5.1.1.4
DE   Proline racemase.
CA   L-proline = D-proline.
DR   Q17ZY4, PRAC_CLOD6 ;  A8DEZ8, PRAC_CLODI ;  Q4DA80, PRCMA_TRYCR;
DR   Q868H8, PRCMB_TRYCR;  Q3SX04, PRCM_BOVIN ;  Q96EM0, PRCM_HUMAN ;
DR   Q9CXA2, PRCM_MOUSE ;  Q5RC28, PRCM_PONAB ;  Q66II5, PRCM_XENTR ;
//
ID   5.1.1.5
DE   Lysine racemase.
CA   L-lysine = D-lysine.
//
ID   5.1.1.6
DE   Threonine racemase.
CA   L-threonine = D-threonine.
CC   -!- Inverts both chiral centers.
//
ID   5.1.1.7
DE   Diaminopimelate epimerase.
CA   LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate.
PR   PROSITE; PDOC01029;
DR   P54897, DAPF1_NOSS1;  Q8YVD0, DAPF2_NOSS1;  B0C312, DAPF_ACAM1 ;
DR   A1TKA9, DAPF_ACIAC ;  Q6F950, DAPF_ACIAD ;  B7GY71, DAPF_ACIB3 ;
DR   B7I5Y5, DAPF_ACIB5 ;  B2HX82, DAPF_ACIBC ;  B0VT30, DAPF_ACIBS ;
DR   A3M804, DAPF_ACIBT ;  B0VDN4, DAPF_ACIBY ;  A0LUZ5, DAPF_ACIC1 ;
DR   A5G1F7, DAPF_ACICJ ;  B9MFT0, DAPF_ACIET ;  A3N2H9, DAPF_ACTP2 ;
DR   B3GYL3, DAPF_ACTP7 ;  B0BRC5, DAPF_ACTPJ ;  A6VQR8, DAPF_ACTSZ ;
DR   A0KFI1, DAPF_AERHH ;  A4SRW9, DAPF_AERS4 ;  B9JCL3, DAPF_AGRRK ;
DR   Q8UC03, DAPF_AGRT5 ;  B9JUB9, DAPF_AGRVS ;  Q0VM18, DAPF_ALCBS ;
DR   Q0ACL9, DAPF_ALHEH ;  B6EP85, DAPF_ALISL ;  A6TRX5, DAPF_ALKMQ ;
DR   A8MH77, DAPF_ALKOO ;  O67693, DAPF_AQUAE ;  Q9LFG2, DAPF_ARATH ;
DR   O29511, DAPF_ARCFU ;  Q5P2V2, DAPF_AROAE ;  B6YS11, DAPF_AZOPC ;
DR   A1K306, DAPF_AZOSB ;  C1DJ56, DAPF_AZOVD ;  A7Z8D3, DAPF_BACA2 ;
DR   C3PDH0, DAPF_BACAA ;  C3LC72, DAPF_BACAC ;  A0RKC7, DAPF_BACAH ;
DR   Q81XR2, DAPF_BACAN ;  B7JDJ2, DAPF_BACC0 ;  Q72YE7, DAPF_BACC1 ;
DR   B7IMV5, DAPF_BACC2 ;  C1EX98, DAPF_BACC3 ;  B7HBI0, DAPF_BACC4 ;
DR   B7HUS8, DAPF_BACC7 ;  A7GUE1, DAPF_BACCN ;  Q816D1, DAPF_BACCR ;
DR   Q632C7, DAPF_BACCZ ;  Q64SY7, DAPF_BACFR ;  Q9K7F0, DAPF_BACHD ;
DR   Q6HBW8, DAPF_BACHK ;  Q65FD6, DAPF_BACLD ;  A8FH15, DAPF_BACP2 ;
DR   O32114, DAPF_BACSU ;  Q8AAB7, DAPF_BACTN ;  A6L7E5, DAPF_BACV8 ;
DR   A9VN01, DAPF_BACWK ;  A1UQV5, DAPF_BARBK ;  Q6G1L7, DAPF_BARHE ;
DR   Q6FYC7, DAPF_BARQU ;  A9IZW1, DAPF_BART1 ;  Q1LTX0, DAPF_BAUCH ;
DR   B2IEM1, DAPF_BEII9 ;  Q7VRM5, DAPF_BLOFL ;  Q491Z7, DAPF_BLOPB ;
DR   C0QZX1, DAPF_BRAHW ;  Q89X45, DAPF_BRAJA ;  A5E915, DAPF_BRASB ;
DR   A4YKA5, DAPF_BRASO ;  B2S885, DAPF_BRUA1 ;  Q2YLR4, DAPF_BRUA2 ;
DR   Q57AW6, DAPF_BRUAB ;  A9M8R8, DAPF_BRUC2 ;  C0RFH7, DAPF_BRUMB ;
DR   Q8YJF0, DAPF_BRUME ;  A5VSQ7, DAPF_BRUO2 ;  B0CIT6, DAPF_BRUSI ;
DR   Q8FYF0, DAPF_BRUSU ;  B8D8F1, DAPF_BUCA5 ;  P57649, DAPF_BUCAI ;
DR   Q8K901, DAPF_BUCAP ;  B8D8A8, DAPF_BUCAT ;  P59582, DAPF_BUCBP ;
DR   Q0BAY6, DAPF_BURCM ;  A3MRQ6, DAPF_BURM7 ;  A2S862, DAPF_BURM9 ;
DR   Q62EZ3, DAPF_BURMA ;  A1V7L3, DAPF_BURMS ;  A3NQ71, DAPF_BURP0 ;
DR   A3N4H9, DAPF_BURP6 ;  B2JJY4, DAPF_BURP8 ;  B2T1P5, DAPF_BURPP ;
DR   Q63YH7, DAPF_BURPS ;  Q2T269, DAPF_BURTA ;  A4JIQ6, DAPF_BURVG ;
DR   Q146W2, DAPF_BURXL ;  A8FNJ1, DAPF_CAMJ8 ;  A7H5P5, DAPF_CAMJD ;
DR   Q9PMD8, DAPF_CAMJE ;  A1W1D0, DAPF_CAMJJ ;  Q5HSQ5, DAPF_CAMJR ;
DR   B9KED6, DAPF_CAMLR ;  Q3AC09, DAPF_CARHZ ;  B8GVW2, DAPF_CAUCN ;
DR   Q9A280, DAPF_CAUCR ;  B0T542, DAPF_CAUSK ;  B3PEI8, DAPF_CELJU ;
DR   Q9PJW2, DAPF_CHLMU ;  Q9Z833, DAPF_CHLPN ;  B0B802, DAPF_CHLT2 ;
DR   Q3KLS0, DAPF_CHLTA ;  B0BC67, DAPF_CHLTB ;  Q8KAX9, DAPF_CHLTE ;
DR   O84437, DAPF_CHLTR ;  Q1QSV1, DAPF_CHRSD ;  Q7NV18, DAPF_CHRVO ;
DR   A5CSL3, DAPF_CLAM3 ;  B0RHB0, DAPF_CLAMS ;  Q97FV2, DAPF_CLOAB ;
DR   Q46185, DAPF_CLOPE ;  A3DK16, DAPF_CLOTH ;  Q48AR8, DAPF_COLP3 ;
DR   C3PGX6, DAPF_CORA7 ;  Q8FPE1, DAPF_COREF ;  A4QEV1, DAPF_CORGB ;
DR   Q8NP73, DAPF_CORGL ;  B6J630, DAPF_COXB1 ;  B6J395, DAPF_COXB2 ;
DR   A9KGY8, DAPF_COXBN ;  A9N9J6, DAPF_COXBR ;  Q83AD4, DAPF_COXBU ;
DR   Q0KF42, DAPF_CUPNH ;  Q476V3, DAPF_CUPPJ ;  B2AGE5, DAPF_CUPTR ;
DR   B8HU20, DAPF_CYAP4 ;  B7KH06, DAPF_CYAP7 ;  B7K1E7, DAPF_CYAP8 ;
DR   Q47JN0, DAPF_DECAR ;  C0QAP3, DAPF_DESAH ;  B1I545, DAPF_DESAP ;
DR   B8IZX7, DAPF_DESDA ;  B8FSD4, DAPF_DESHD ;  A4J568, DAPF_DESRM ;
DR   A7ZU14, DAPF_ECO24 ;  B7UNC6, DAPF_ECO27 ;  B7MH73, DAPF_ECO45 ;
DR   B7L969, DAPF_ECO55 ;  P0A6K2, DAPF_ECO57 ;  B5YY56, DAPF_ECO5E ;
DR   B7NTD3, DAPF_ECO7I ;  B7MR29, DAPF_ECO81 ;  B7M611, DAPF_ECO8A ;
DR   C4ZZ73, DAPF_ECOBW ;  B1XAH6, DAPF_ECODH ;  A8A6R7, DAPF_ECOHS ;
DR   Q0TAR6, DAPF_ECOL5 ;  Q8FBN6, DAPF_ECOL6 ;  B1IW95, DAPF_ECOLC ;
DR   P0A6K1, DAPF_ECOLI ;  B7NFB1, DAPF_ECOLU ;  B1LLY0, DAPF_ECOSM ;
DR   C5BBD4, DAPF_EDWI9 ;  B2KDH2, DAPF_ELUMP ;  A4WG08, DAPF_ENT38 ;
DR   Q838I3, DAPF_ENTFA ;  A7MQK2, DAPF_ENTS8 ;  Q6CZG8, DAPF_ERWCT ;
DR   B2VI49, DAPF_ERWT9 ;  Q2NBR6, DAPF_ERYLH ;  B7LU47, DAPF_ESCF3 ;
DR   C4Z900, DAPF_EUBR3 ;  A6GYX5, DAPF_FLAPJ ;  C1A8U3, DAPF_GEMAT ;
DR   Q5KVP4, DAPF_GEOKA ;  C5D729, DAPF_GEOSW ;  A4ISE8, DAPF_GEOTN ;
DR   Q5FQZ4, DAPF_GLUOX ;  Q0BS04, DAPF_GRABC ;  Q7VPN0, DAPF_HAEDU ;
DR   Q4QME8, DAPF_HAEI8 ;  A5UDX5, DAPF_HAEIE ;  A5UHQ4, DAPF_HAEIG ;
DR   P44859, DAPF_HAEIN ;  B8F878, DAPF_HAEPS ;  Q0I572, DAPF_HAES1 ;
DR   B0UWU6, DAPF_HAES2 ;  Q2SQ64, DAPF_HAHCH ;  A1WWB3, DAPF_HALHL ;
DR   B8CX90, DAPF_HALOH ;  B0TGR9, DAPF_HELMI ;  B6JLE8, DAPF_HELP2 ;
DR   B5Z6T7, DAPF_HELPG ;  Q1CTW0, DAPF_HELPH ;  Q9ZLR5, DAPF_HELPJ ;
DR   B2UTR2, DAPF_HELPS ;  O25290, DAPF_HELPY ;  A4G980, DAPF_HERAR ;
DR   B4U9P0, DAPF_HYDS0 ;  Q5QUS6, DAPF_IDILO ;  Q88V90, DAPF_LACPL ;
DR   Q1WTU5, DAPF_LACS1 ;  C1D8Q0, DAPF_LARHH ;  Q5X822, DAPF_LEGPA ;
DR   A5IHM9, DAPF_LEGPC ;  Q5ZYK6, DAPF_LEGPH ;  Q5WZH5, DAPF_LEGPL ;
DR   Q6AE05, DAPF_LEIXX ;  B0SC36, DAPF_LEPBA ;  Q04W97, DAPF_LEPBJ ;
DR   Q04X60, DAPF_LEPBL ;  B1Y6S6, DAPF_LEPCP ;  Q72W63, DAPF_LEPIC ;
DR   Q8F9V5, DAPF_LEPIN ;  Q929Z7, DAPF_LISIN ;  C1KWW2, DAPF_LISMC ;
DR   Q71Y02, DAPF_LISMF ;  B8DBR3, DAPF_LISMH ;  Q8Y5N9, DAPF_LISMO ;
DR   A0AKC4, DAPF_LISW6 ;  A0LE31, DAPF_MAGSM ;  Q65RL9, DAPF_MANSM ;
DR   Q11CW3, DAPF_MESSB ;  A6UTH4, DAPF_META3 ;  B7KQM2, DAPF_METC4 ;
DR   A9W6A5, DAPF_METEP ;  Q58519, DAPF_METJA ;  Q8TY71, DAPF_METKA ;
DR   A4FXV0, DAPF_METM5 ;  A9AB27, DAPF_METM6 ;  A6VFK8, DAPF_METM7 ;
DR   Q6LYS1, DAPF_METMP ;  B8I9H6, DAPF_METNO ;  B1ZDT1, DAPF_METPB ;
DR   A2SKV9, DAPF_METPP ;  B0UCI8, DAPF_METS4 ;  B8EM14, DAPF_METSB ;
DR   O27389, DAPF_METTH ;  A0B6C1, DAPF_METTP ;  B0JJ58, DAPF_MICAN ;
DR   Q2RK34, DAPF_MOOTA ;  A0QIQ8, DAPF_MYCA1 ;  B1MD00, DAPF_MYCA9 ;
DR   P63898, DAPF_MYCBO ;  A1KM64, DAPF_MYCBP ;  C1AFI5, DAPF_MYCBT ;
DR   A4TCN3, DAPF_MYCGI ;  B8ZQU1, DAPF_MYCLB ;  P46814, DAPF_MYCLE ;
DR   B2HL16, DAPF_MYCMM ;  Q73W21, DAPF_MYCPA ;  A0QVY0, DAPF_MYCS2 ;
DR   A3PYF9, DAPF_MYCSJ ;  A1UEZ9, DAPF_MYCSK ;  A5U678, DAPF_MYCTA ;
DR   P63897, DAPF_MYCTU ;  A0PT80, DAPF_MYCUA ;  A1T7U8, DAPF_MYCVP ;
DR   B2A663, DAPF_NATTJ ;  Q9JV69, DAPF_NEIMA ;  Q9K060, DAPF_NEIMB ;
DR   Q0AIP0, DAPF_NITEC ;  Q82U84, DAPF_NITEU ;  Q1QHJ3, DAPF_NITHX ;
DR   Q2Y5Z0, DAPF_NITMU ;  Q3JEA2, DAPF_NITOC ;  A6Q160, DAPF_NITSB ;
DR   B2J3A7, DAPF_NOSP7 ;  Q8ENX2, DAPF_OCEIH ;  A6WXE4, DAPF_OCHA4 ;
DR   B6JAP3, DAPF_OLICO ;  A2ZLS4, DAPF_ORYSI ;  Q2QNF7, DAPF_ORYSJ ;
DR   A6L8U3, DAPF_PARD8 ;  P57962, DAPF_PASMU ;  C6DHB7, DAPF_PECCP ;
DR   A5D193, DAPF_PELTS ;  Q4FP10, DAPF_PELUB ;  B4RCE2, DAPF_PHEZH ;
DR   Q7MYN5, DAPF_PHOLL ;  Q6LLN5, DAPF_PHOPR ;  A2C243, DAPF_PROM1 ;
DR   B4F1X7, DAPF_PROMH ;  Q7V7M5, DAPF_PROMM ;  Q46L14, DAPF_PROMT ;
DR   Q48C02, DAPF_PSE14 ;  Q15NG5, DAPF_PSEA6 ;  A6VE52, DAPF_PSEA7 ;
DR   B7V5G9, DAPF_PSEA8 ;  Q02E84, DAPF_PSEAB ;  Q51564, DAPF_PSEAE ;
DR   Q1I303, DAPF_PSEE4 ;  O05322, DAPF_PSEFL ;  Q3IEW3, DAPF_PSEHT ;
DR   A4XNX4, DAPF_PSEMY ;  Q3K4R8, DAPF_PSEPF ;  B0KQ41, DAPF_PSEPG ;
DR   Q88CF3, DAPF_PSEPK ;  B1J1W0, DAPF_PSEPW ;  Q88B09, DAPF_PSESM ;
DR   Q500B6, DAPF_PSEU2 ;  A4VGW5, DAPF_PSEU5 ;  Q4FV85, DAPF_PSYA2 ;
DR   Q1QE99, DAPF_PSYCK ;  A1SQZ9, DAPF_PSYIN ;  A5WCB3, DAPF_PSYWF ;
DR   Q1LS37, DAPF_RALME ;  B2UD25, DAPF_RALPJ ;  Q8Y344, DAPF_RALSO ;
DR   Q2K386, DAPF_RHIEC ;  Q98EB6, DAPF_RHILO ;  B5ZTH4, DAPF_RHILW ;
DR   Q92L46, DAPF_RHIME ;  B6IP82, DAPF_RHOCS ;  C0ZYN8, DAPF_RHOE4 ;
DR   Q21SV0, DAPF_RHOFD ;  C1B393, DAPF_RHOOB ;  Q2J390, DAPF_RHOP2 ;
DR   Q07UV4, DAPF_RHOP5 ;  Q6ND59, DAPF_RHOPA ;  Q21CU6, DAPF_RHOPB ;
DR   Q13DT7, DAPF_RHOPS ;  B3Q862, DAPF_RHOPT ;  Q3IZB6, DAPF_RHOS4 ;
DR   Q0S1N7, DAPF_RHOSR ;  C3PNE1, DAPF_RICAE ;  A8GND7, DAPF_RICAH ;
DR   A8GWH4, DAPF_RICB8 ;  Q1RIT1, DAPF_RICBR ;  A8EZ08, DAPF_RICCK ;
DR   Q92I41, DAPF_RICCN ;  Q4ULS7, DAPF_RICFE ;  A8F1I9, DAPF_RICM5 ;
DR   Q9ZDB7, DAPF_RICPR ;  C4K2A3, DAPF_RICPU ;  B0BXH3, DAPF_RICRO ;
DR   A8GS10, DAPF_RICRS ;  Q68WW4, DAPF_RICTY ;  A1AWJ5, DAPF_RUTMC ;
DR   Q21P78, DAPF_SACD2 ;  B5EZS3, DAPF_SALA4 ;  B5FNU5, DAPF_SALDC ;
DR   B4TB37, DAPF_SALHS ;  B4SZ51, DAPF_SALNS ;  Q5PKM6, DAPF_SALPA ;
DR   A9MY70, DAPF_SALPB ;  B5BIV6, DAPF_SALPK ;  B4TNV9, DAPF_SALSV ;
DR   P0A1F3, DAPF_SALTI ;  P0A1F2, DAPF_SALTY ;  A8G852, DAPF_SERP5 ;
DR   A1SAP5, DAPF_SHEAM ;  B8E690, DAPF_SHEB2 ;  A3D9Q0, DAPF_SHEB5 ;
DR   A6WTF5, DAPF_SHEB8 ;  A9L5F5, DAPF_SHEB9 ;  Q12S90, DAPF_SHEDO ;
DR   Q088K8, DAPF_SHEFN ;  A3Q9P7, DAPF_SHELP ;  Q8E9H5, DAPF_SHEON ;
DR   A4YBF7, DAPF_SHEPC ;  A0KS65, DAPF_SHESA ;  A8G0W0, DAPF_SHESH ;
DR   Q0HN95, DAPF_SHESM ;  Q0HQJ2, DAPF_SHESR ;  A1RPD2, DAPF_SHESW ;
DR   B1KQD0, DAPF_SHEWM ;  B2TUW5, DAPF_SHIB3 ;  Q0SZ00, DAPF_SHIF8 ;
DR   Q2NQF4, DAPF_SODGM ;  Q1GPI7, DAPF_SPHAL ;  A5VAG4, DAPF_SPHWW ;
DR   O69969, DAPF_STRCO ;  Q31LW2, DAPF_SYNE7 ;  Q2JUV6, DAPF_SYNJA ;
DR   Q2JLR0, DAPF_SYNJB ;  B1XP39, DAPF_SYNP2 ;  Q5N013, DAPF_SYNP6 ;
DR   P74667, DAPF_SYNY3 ;  C5BUL6, DAPF_TERTT ;  Q8DGM2, DAPF_THEEB ;
DR   Q47RR3, DAPF_THEFY ;  Q8R9S4, DAPF_THETN ;  B8GT89, DAPF_THISH ;
DR   C4LDU8, DAPF_TOLAT ;  Q116P1, DAPF_TRIEI ;  Q0W3B6, DAPF_UNCMA ;
DR   C5CND4, DAPF_VARPS ;  A5CWN5, DAPF_VESOH ;  A5F4I6, DAPF_VIBC3 ;
DR   Q9KVL6, DAPF_VIBCH ;  Q5E1W7, DAPF_VIBF1 ;  A7N0W0, DAPF_VIBHB ;
DR   Q87KJ4, DAPF_VIBPA ;  B7VMD4, DAPF_VIBSL ;  Q8DD81, DAPF_VIBVU ;
DR   Q7MQC1, DAPF_VIBVY ;  Q8D2T4, DAPF_WIGBR ;  Q5GSB8, DAPF_WOLTR ;
DR   C0R4N2, DAPF_WOLWR ;  Q8PPQ1, DAPF_XANAC ;  Q3BXU3, DAPF_XANC5 ;
DR   Q4UYY2, DAPF_XANC8 ;  B0RNK1, DAPF_XANCB ;  Q8P548, DAPF_XANCP ;
DR   Q2NYV5, DAPF_XANOM ;  B2IA16, DAPF_XYLF2 ;  Q9PD98, DAPF_XYLFA ;
DR   B0U6U5, DAPF_XYLFM ;  Q87DI4, DAPF_XYLFT ;  A1JI90, DAPF_YERE8 ;
DR   A7FD74, DAPF_YERP3 ;  Q1CBM6, DAPF_YERPA ;  B2K072, DAPF_YERPB ;
DR   P46357, DAPF_YERPE ;  A9R8K5, DAPF_YERPG ;  Q1CNH8, DAPF_YERPN ;
DR   A4TRA3, DAPF_YERPP ;  Q66FZ5, DAPF_YERPS ;  B1JPE1, DAPF_YERPY ;
DR   Q5NNL4, DAPF_ZYMMO ;
//
ID   5.1.1.8
DE   4-hydroxyproline epimerase.
AN   Hydroxyproline 2-epimerase.
AN   Hydroxyproline epimerase.
CA   Trans-4-hydroxy-L-proline = cis-4-hydroxy-D-proline.
CC   -!- Also interconverts trans-4-hydroxy-D-proline and cis-4-hydroxy-L-
CC       proline.
DR   B2S7L7, HYPRE_BRUA1;  Q2YLF3, HYPRE_BRUA2;  Q57B94, HYPRE_BRUAB;
DR   A9M832, HYPRE_BRUC2;  Q8YJ29, HYPRE_BRUME;  A5VSD5, HYPRE_BRUO2;
DR   A9WWR5, HYPRE_BRUSI;  Q8FYS0, HYPRE_BRUSU;  A0AZQ0, HYPRE_BURCH;
DR   Q63NG7, HYPRE_BURPS;  Q9I476, HYPRE_PSEAE;
//
ID   5.1.1.9
DE   Arginine racemase.
CA   L-arginine = D-arginine.
CF   Pyridoxal 5'-phosphate.
//
ID   5.1.1.10
DE   Amino-acid racemase.
CA   An L-amino acid = a D-amino acid.
CF   Pyridoxal 5'-phosphate.
//
ID   5.1.1.11
DE   Phenylalanine racemase (ATP-hydrolyzing).
CA   ATP + L-phenylalanine + H(2)O = AMP + diphosphate + D-phenylalanine.
PR   PROSITE; PDOC00427;
DR   O68008, BACC_BACLI ;  P0C061, GRSA_ANEMI ;  P0C062, GRSA_BREBE ;
DR   P09095, TYCA_BREPA ;  O30408, TYCB_BREPA ;
//
ID   5.1.1.12
DE   Ornithine racemase.
CA   L-ornithine = D-ornithine.
DR   O68007, BACB_BACLI ;
//
ID   5.1.1.13
DE   Aspartate racemase.
CA   L-aspartate = D-aspartate.
CC   -!- Also acts, at half the rate, on L-alanine.
PR   PROSITE; PDOC00714;
DR   O68008, BACC_BACLI ;  P83989, RACD_ANABR ;  P29079, RACD_ENTFC ;
//
ID   5.1.1.14
DE   Nocardicin-A epimerase.
CA   Isonocardicin A = nocardicin A.
CC   -!- The (9'S) configuration of isonocardicin A is converted into the
CC       (9'R) configuration.
//
ID   5.1.1.15
DE   2-aminohexano-6-lactam racemase.
AN   2-amino-hexano-6-lactam racemase.
AN   Alpha-amino-epsilon-caprolactam racemase.
CA   L-2-aminohexano-6-lactam = D-2-aminohexano-6-lactam.
CF   Pyridoxal 5'-phosphate.
CC   -!- Also interconverts 2-aminopentano-5-lactam (alpha-amino-delta-
CC       valerolactam) and 2-amino-4-thiahexano-6-lactam (where S replaces
CC       CH(2) of C-4).
CC   -!- It does not catalyze the racemisation of alpha-amino acids but has
CC       some transaminase activity with them.
//
ID   5.1.1.16
DE   Protein-serine epimerase.
AN   Protein-serine racemase.
CA   [Protein]-L-serine = [protein]-D-serine.
CC   -!- The enzyme specifically interconverts the configuration of Ser-46 of
CC       the peptide omega-agatoxin-KT, found in the venom of the funnel web
CC       spider, Agelenopsis aperta, but not that of the other serine residue,
CC       Ser-28.
//
ID   5.1.1.17
DE   Isopenicillin-N epimerase.
CA   Isopenicillin N = penicillin N.
CF   Pyridoxal 5'-phosphate.
CC   -!- Epimerization at C-5 of the 5-amino-5-carboxypentanoyl group to form
CC       penicillin N is required to make a substrate for EC 1.14.20.1,
CC       to produce cephalosporins.
CC   -!- Forms part of the penicillin biosynthesis pathway.
DR   Q03046, CEFD_NOCLA ;  P18549, CEFD_STRCL ;
//
ID   5.1.1.18
DE   Serine racemase.
CA   L-serine = D-serine.
CF   Pyridoxal 5'-phosphate.
CC   -!- Highly selective for L-serine as substrate.
CC   -!- D-serine is found in type-II astrocytes in mammalian brain, where it
CC       appears to be an endogenous ligand of the glycine site of N-methyl-D-
CC       aspartate (NMDA) receptors.
CC   -!- The reaction can also occur in the reverse direction but does so more
CC       slowly at physiological serine concentrations.
PR   PROSITE; PDOC00149;
DR   A0JNI4, SRR_BOVIN  ;  Q54HH2, SRR_DICDI  ;  Q9GZT4, SRR_HUMAN  ;
DR   Q9QZX7, SRR_MOUSE  ;  Q76EQ0, SRR_RAT    ;  O59791, SRR_SCHPO  ;
//
ID   5.1.2.1
DE   Lactate racemase.
AN   Hydroxyacid racemase.
AN   Lactic acid racemase.
AN   Lacticoracemase.
CA   (S)-lactate = (R)-lactate.
//
ID   5.1.2.2
DE   Mandelate racemase.
CA   (S)-mandelate = (R)-mandelate.
PR   PROSITE; PDOC00706;
DR   P11444, MANR_PSEPU ;
//
ID   5.1.2.3
DE   3-hydroxybutyryl-CoA epimerase.
CA   (S)-3-hydroxybutanoyl-CoA = (R)-3-hydroxybutanoyl-CoA.
DR   Q9ZPI6, AIM1_ARATH ;  Q6FF68, FADB_ACIAD ;  B7H1I0, FADB_ACIB3 ;
DR   B7I3P1, FADB_ACIB5 ;  B2I2J9, FADB_ACIBC ;  B0VLX4, FADB_ACIBS ;
DR   B0VE45, FADB_ACIBY ;  A0KEL1, FADB_AERHH ;  A4STF2, FADB_AERS4 ;
DR   B6EGU2, FADB_ALISL ;  A8ACZ4, FADB_CITK8 ;  Q489W3, FADB_COLP3 ;
DR   A7ZU51, FADB_ECO24 ;  B7UNH4, FADB_ECO27 ;  B7MHD1, FADB_ECO45 ;
DR   B7L9A7, FADB_ECO55 ;  Q8X8I2, FADB_ECO57 ;  B5YY93, FADB_ECO5E ;
DR   B7NV20, FADB_ECO7I ;  B7N2F2, FADB_ECO81 ;  B7M649, FADB_ECO8A ;
DR   C5A020, FADB_ECOBW ;  B1XAK8, FADB_ECODH ;  A8A6V1, FADB_ECOHS ;
DR   Q0TAL0, FADB_ECOL5 ;  Q8FBI2, FADB_ECOL6 ;  B1IW61, FADB_ECOLC ;
DR   P21177, FADB_ECOLI ;  B7NFE7, FADB_ECOLU ;  B6I4I6, FADB_ECOSE ;
DR   B1LM32, FADB_ECOSM ;  Q1R466, FADB_ECOUT ;  A4WFX4, FADB_ENT38 ;
DR   Q9F0Y7, FADB_ENTCL ;  A7MQP0, FADB_ENTS8 ;  Q6DAP5, FADB_ERWCT ;
DR   B7LTY9, FADB_ESCF3 ;  Q5QXH7, FADB_IDILO ;  B5XYH0, FADB_KLEP3 ;
DR   A6TGM4, FADB_KLEP7 ;  Q7MZ92, FADB_PHOLL ;  Q6LW06, FADB_PHOPR ;
DR   Q48GW3, FADB_PSE14 ;  A6V382, FADB_PSEA7 ;  B7UYR6, FADB_PSEA8 ;
DR   Q02PH8, FADB_PSEAB ;  Q9HZJ2, FADB_PSEAE ;  Q1I7D4, FADB_PSEE4 ;
DR   Q4KFC4, FADB_PSEF5 ;  P28793, FADB_PSEFR ;  C3K613, FADB_PSEFS ;
DR   A4XSM8, FADB_PSEMY ;  Q93Q12, FADB_PSEOL ;  A5W6H0, FADB_PSEP1 ;
DR   Q3K9D8, FADB_PSEPF ;  B0KH74, FADB_PSEPG ;  Q88L02, FADB_PSEPK ;
DR   Q9AHY3, FADB_PSEPU ;  B1J5A5, FADB_PSEPW ;  Q87ZB2, FADB_PSESM ;
DR   Q4ZRA0, FADB_PSEU2 ;  A4VKA3, FADB_PSEU5 ;  Q4FQC6, FADB_PSYA2 ;
DR   Q1Q8J9, FADB_PSYCK ;  A5WH99, FADB_PSYWF ;  B5EZW0, FADB_SALA4 ;
DR   Q57HM6, FADB_SALCH ;  B5QW85, FADB_SALEP ;  B5RFL6, FADB_SALG2 ;
DR   B4SZ85, FADB_SALNS ;  Q5PKQ2, FADB_SALPA ;  A9MYB0, FADB_SALPB ;
DR   B5BIZ0, FADB_SALPK ;  B4TNZ1, FADB_SALSV ;  Q8Z3C6, FADB_SALTI ;
DR   Q9L6L5, FADB_SALTY ;  A8G8D1, FADB_SERP5 ;  A1S1I8, FADB_SHEAM ;
DR   B8E3R3, FADB_SHEB2 ;  A3CYJ4, FADB_SHEB5 ;  A6WHA0, FADB_SHEB8 ;
DR   A9KU91, FADB_SHEB9 ;  Q08A39, FADB_SHEFN ;  B0TLB9, FADB_SHEHH ;
DR   A3Q8U4, FADB_SHELP ;  Q8EKR9, FADB_SHEON ;  A8GYG0, FADB_SHEPA ;
DR   A4Y1B6, FADB_SHEPC ;  B8CH91, FADB_SHEPW ;  A0KR50, FADB_SHESA ;
DR   A8FP63, FADB_SHESH ;  Q0HPB7, FADB_SHESM ;  Q0I0T3, FADB_SHESR ;
DR   A1RDW6, FADB_SHESW ;  B1KCZ3, FADB_SHEWM ;  B2TVJ5, FADB_SHIB3 ;
DR   Q32A21, FADB_SHIDS ;  Q0SZ36, FADB_SHIF8 ;  Q83PG1, FADB_SHIFL ;
DR   Q3YVC1, FADB_SHISS ;  A5F465, FADB_VIBC3 ;  Q9KNI1, FADB_VIBCH ;
DR   C3LSI3, FADB_VIBCM ;  Q5E8X6, FADB_VIBF1 ;  B5FEW8, FADB_VIBFM ;
DR   A7N1D2, FADB_VIBHB ;  Q87TN9, FADB_VIBPA ;  B7VGL4, FADB_VIBSL ;
DR   Q8DDK6, FADB_VIBVU ;  Q7MQH9, FADB_VIBVY ;  A1JIG4, FADB_YERE8 ;
DR   A7FDF2, FADB_YERP3 ;  Q1C2C4, FADB_YERPA ;  B2K0Z6, FADB_YERPB ;
DR   Q8ZAN0, FADB_YERPE ;  A9R754, FADB_YERPG ;  Q1CN99, FADB_YERPN ;
DR   A4TR27, FADB_YERPP ;  Q66FR8, FADB_YERPS ;  B1JP63, FADB_YERPY ;
DR   A8ADP2, FADJ_CITK8 ;  A7ZPF8, FADJ_ECO24 ;  B7UFZ8, FADJ_ECO27 ;
DR   B7MGV7, FADJ_ECO45 ;  B7LBJ5, FADJ_ECO55 ;  Q8XCP2, FADJ_ECO57 ;
DR   B5YXY4, FADJ_ECO5E ;  B7NP24, FADJ_ECO7I ;  B7MY16, FADJ_ECO81 ;
DR   B7M6M2, FADJ_ECO8A ;  C4ZVN2, FADJ_ECOBW ;  B1X9L4, FADJ_ECODH ;
DR   A8A2L0, FADJ_ECOHS ;  A1ADI8, FADJ_ECOK1 ;  Q0TFA6, FADJ_ECOL5 ;
DR   Q8FFG4, FADJ_ECOL6 ;  B1IXA5, FADJ_ECOLC ;  P77399, FADJ_ECOLI ;
DR   B7N5V2, FADJ_ECOLU ;  B6I6Q4, FADJ_ECOSE ;  B1LME7, FADJ_ECOSM ;
DR   Q1R972, FADJ_ECOUT ;  A4WCW6, FADJ_ENT38 ;  A7MH81, FADJ_ENTS8 ;
DR   Q6D2L7, FADJ_ERWCT ;  B7LLD0, FADJ_ESCF3 ;  Q5QXM1, FADJ_IDILO ;
DR   B5XVW2, FADJ_KLEP3 ;  A6TC19, FADJ_KLEP7 ;  C6DAL7, FADJ_PECCP ;
DR   Q7N288, FADJ_PHOLL ;  Q6LTK3, FADJ_PHOPR ;  B5EZR9, FADJ_SALA4 ;
DR   Q57LW6, FADJ_SALCH ;  B5FPN1, FADJ_SALDC ;  B5R3R9, FADJ_SALEP ;
DR   B5RCL3, FADJ_SALG2 ;  B4TCA8, FADJ_SALHS ;  B4SZR0, FADJ_SALNS ;
DR   Q5PCX6, FADJ_SALPA ;  A9N453, FADJ_SALPB ;  B5BBA1, FADJ_SALPK ;
DR   B4TQC2, FADJ_SALSV ;  Q8Z4Z0, FADJ_SALTI ;  Q8ZNA7, FADJ_SALTY ;
DR   A8GH86, FADJ_SERP5 ;  A1S7L6, FADJ_SHEAM ;  A3D684, FADJ_SHEB5 ;
DR   A6WQ25, FADJ_SHEB8 ;  Q07ZP8, FADJ_SHEFN ;  B0TL21, FADJ_SHEHH ;
DR   A3QFP3, FADJ_SHELP ;  Q8ECP7, FADJ_SHEON ;  A4Y897, FADJ_SHEPC ;
DR   A0KV76, FADJ_SHESA ;  Q0HKD1, FADJ_SHESM ;  Q0HWN3, FADJ_SHESR ;
DR   A1RI92, FADJ_SHESW ;  B2TWV4, FADJ_SHIB3 ;  Q31YB7, FADJ_SHIBS ;
DR   Q32DJ4, FADJ_SHIDS ;  Q0T2E6, FADJ_SHIF8 ;  Q83QQ0, FADJ_SHIFL ;
DR   Q3YZM2, FADJ_SHISS ;  A5F2P2, FADJ_VIBC3 ;  Q9KT58, FADJ_VIBCH ;
DR   Q5E3U1, FADJ_VIBF1 ;  A7MS61, FADJ_VIBHB ;  Q87MM3, FADJ_VIBPA ;
DR   Q8DB47, FADJ_VIBVU ;  Q7MIS5, FADJ_VIBVY ;  A1JK30, FADJ_YERE8 ;
DR   A7FGK1, FADJ_YERP3 ;  Q1C660, FADJ_YERPA ;  Q8ZD45, FADJ_YERPE ;
DR   Q1CHK2, FADJ_YERPN ;  A4TM82, FADJ_YERPP ;  Q668V1, FADJ_YERPS ;
DR   Q9ZPI5, MFP2_ARATH ;  O49809, MFPA_BRANA ;  Q39659, MFPA_CUCSA ;
DR   Q8W1L6, MFP_ORYSJ  ;
//
ID   5.1.2.4
DE   Acetoin racemase.
AN   Acetylmethylcarbinol racemase.
CA   (S)-acetoin = (R)-acetoin.
//
ID   5.1.2.5
DE   Tartrate epimerase.
CA   (R,R)-tartrate = meso-tartrate.
//
ID   5.1.2.6
DE   Isocitrate epimerase.
CA   (1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate = (1S,2S)-1-hydroxypropane-
CA   1,2,3-tricarboxylate.
CC   -!- (1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate is the commonly
CC       occurring isomer of isocitrate.
//
ID   5.1.3.1
DE   Ribulose-phosphate 3-epimerase.
AN   D-ribulose phosphate-3-epimerase.
AN   D-ribulose-5-phosphate epimerase.
AN   D-xylulose-5-phosphate 3-epimerase.
AN   Erythrose-4-phosphate epimerase.
AN   Pentose-5-phosphate 3-epimerase.
AN   Phosphoribulose epimerase.
AN   Xylulose phosphate 3-epimerase.
CA   D-ribulose 5-phosphate = D-xylulose 5-phosphate.
CC   -!- Also converts D-erythrose 4-phosphate into D-erythrulose 4-phosphate
CC       and D-threose 4-phosphate.
PR   PROSITE; PDOC00833;
DR   Q9SE42, RPE1_ORYSJ ;  P40117, RPEC_CUPNH ;  Q04539, RPEP_CUPNH ;
DR   O67098, RPE_AQUAE  ;  Q755M2, RPE_ASHGO  ;  O34557, RPE_BACSU  ;
DR   P57603, RPE_BUCAI  ;  Q8K940, RPE_BUCAP  ;  Q89A59, RPE_BUCBP  ;
DR   Q6FL81, RPE_CANGA  ;  Q9PKR7, RPE_CHLMU  ;  Q9Z8Z9, RPE_CHLPN  ;
DR   O84123, RPE_CHLTR  ;  P0AG09, RPE_ECO57  ;  P0AG08, RPE_ECOL6  ;
DR   P0AG07, RPE_ECOLI  ;  Q8SRP6, RPE_ENCCU  ;  P44756, RPE_HAEIN  ;
DR   Q9ZJ75, RPE_HELPJ  ;  P56188, RPE_HELPY  ;  Q96AT9, RPE_HUMAN  ;
DR   Q58093, RPE_METJA  ;  Q8VEE0, RPE_MOUSE  ;  P65761, RPE_MYCBO  ;
DR   P47358, RPE_MYCGE  ;  Q9CCP9, RPE_MYCLE  ;  P75522, RPE_MYCPN  ;
DR   P65760, RPE_MYCTU  ;  Q9ZTP5, RPE_ORYSJ  ;  Q5R5Y2, RPE_PONAB  ;
DR   P51012, RPE_RHOCA  ;  P51013, RPE_RHORU  ;  O14105, RPE_SCHPO  ;
DR   P45455, RPE_SERMA  ;  P0AG10, RPE_SHIFL  ;  Q43843, RPE_SOLTU  ;
DR   Q43157, RPE_SPIOL  ;  Q9L0Z5, RPE_STRCO  ;  P74061, RPE_SYNY3  ;
DR   O66107, RPE_TREPA  ;  P46969, RPE_YEAST  ;
//
ID   5.1.3.2
DE   UDP-glucose 4-epimerase.
AN   Galactowaldenase.
AN   UDP-galactose 4-epimerase.
AN   Uridine diphosphate galactose 4-epimerase.
AN   Uridine diphospho-galactose-4-epimerase.
CA   UDP-glucose = UDP-galactose.
CF   NAD.
CC   -!- Also acts on UDP-2-deoxyglucose.
DR   A8GN21, CAPD_RICAH ;  A8GWP0, CAPD_RICB8 ;  Q1RIM4, CAPD_RICBR ;
DR   A8EZA9, CAPD_RICCK ;  Q92IG3, CAPD_RICCN ;  Q4UM33, CAPD_RICFE ;
DR   A8F1A5, CAPD_RICM5 ;  Q9ZDJ5, CAPD_RICPR ;  A8GRN9, CAPD_RICRS ;
DR   Q8L2J6, CAPD_RICTY ;  Q59083, EXOB_AZOBR ;  Q59745, EXOB_RHILT ;
DR   P26503, EXOB_RHIME ;  P56600, GAL10_CANMA;  P09609, GAL10_KLULA;
DR   P40801, GAL10_PACTA;  Q9HDU3, GAL10_SCHPO;  P04397, GAL10_YEAST;
DR   Q42605, GALE1_ARATH;  O65780, GALE1_CYATE;  Q43070, GALE1_PEA  ;
DR   Q9SN58, GALE2_ARATH;  O65781, GALE2_CYATE;  Q9T0A7, GALE3_ARATH;
DR   Q9KDV3, GALE_BACHD ;  P55180, GALE_BACSU ;  P33119, GALE_CORDI ;
DR   Q45291, GALE_CORGL ;  Q553X7, GALE_DICDI ;  Q9W0P5, GALE_DROME ;
DR   P09147, GALE_ECOLI ;  P35673, GALE_ERWAM ;  P24325, GALE_HAEIN ;
DR   Q14376, GALE_HUMAN ;  P45602, GALE_KLEPN ;  O84903, GALE_LACCA ;
DR   Q7WTB1, GALE_LACHE ;  Q57664, GALE_METJA ;  Q8R059, GALE_MOUSE ;
DR   P47364, GALE_MYCGE ;  P75517, GALE_MYCPN ;  Q05026, GALE_NEIGO ;
DR   P56997, GALE_NEIMA ;  P56985, GALE_NEIMB ;  P56986, GALE_NEIMC ;
DR   Q59678, GALE_PASHA ;  Q9CNY5, GALE_PASMU ;  Q5R8D0, GALE_PONAB ;
DR   P18645, GALE_RAT   ;  Q56093, GALE_SALTI ;  P22715, GALE_SALTY ;
DR   P13226, GALE_STRLI ;  P96995, GALE_STRMU ;  P21977, GALE_STRTR ;
DR   Q56623, GALE_VIBCH ;  Q57301, GALE_YEREN ;  Q9F7D4, GALE_YERPE ;
//
ID   5.1.3.3
DE   Aldose 1-epimerase.
AN   Aldose mutarotase.
AN   Mutarotase.
CA   Alpha-D-glucose = beta-D-glucose.
CC   -!- Also acts on L-arabinose, D-xylose, D-galactose, maltose and lactose.
PR   PROSITE; PDOC00471;
DR   P56600, GAL10_CANMA;  P09609, GAL10_KLULA;  P40801, GAL10_PACTA;
DR   Q9HDU3, GAL10_SCHPO;  P04397, GAL10_YEAST;  P05149, GALM_ACICA ;
DR   P39840, GALM_BACSU ;  Q5EA79, GALM_BOVIN ;  P0A9C3, GALM_ECOLI ;
DR   P31765, GALM_HAEIN ;  Q96C23, GALM_HUMAN ;  Q00053, GALM_LACHE ;
DR   Q8K157, GALM_MOUSE ;  Q9GKX6, GALM_PIG   ;  Q5R8U1, GALM_PONAB ;
DR   Q66HG4, GALM_RAT   ;  P0A9C4, GALM_SHIFL ;  P21955, GALM_STRTR ;
//
ID   5.1.3.4
DE   L-ribulose-5-phosphate 4-epimerase.
AN   L-ribulose 5-phosphate 4-epimerase.
AN   L-ribulose-phosphate 4-epimerase.
AN   L-ru5P.
AN   Phosphoribulose isomerase.
AN   Ribulose phosphate 4-epimerase.
CA   L-ribulose 5-phosphate = D-xylulose 5-phosphate.
CF   Divalent cation.
DR   Q9KBQ4, ARAD_BACHD ;  P94525, ARAD_BACSU ;  P08203, ARAD_ECOLI ;
DR   Q9S469, ARAD_GEOSE ;  P06190, ARAD_SALTY ;  P37680, SGBE_ECOLI ;
DR   A7ZV69, ULAF_ECO24 ;  B7MLK3, ULAF_ECO45 ;  B7LCQ8, ULAF_ECO55 ;
DR   Q8XDI4, ULAF_ECO57 ;  B5Z2K4, ULAF_ECO5E ;  B7NTQ4, ULAF_ECO7I ;
DR   B7MSS8, ULAF_ECO81 ;  B7M9G0, ULAF_ECO8A ;  C4ZR75, ULAF_ECOBW ;
DR   B1XDU9, ULAF_ECODH ;  A8A7U4, ULAF_ECOHS ;  A1AJA3, ULAF_ECOK1 ;
DR   Q0T9J5, ULAF_ECOL5 ;  Q8FAI6, ULAF_ECOL6 ;  B1IT08, ULAF_ECOLC ;
DR   P39306, ULAF_ECOLI ;  B7NGD2, ULAF_ECOLU ;  B6I2A3, ULAF_ECOSE ;
DR   B1LQL8, ULAF_ECOSM ;  B7LLY0, ULAF_ESCF3 ;  P75289, ULAF_MYCPN ;
DR   B5F3B4, ULAF_SALA4 ;  Q57GJ4, ULAF_SALCH ;  Q5PJ61, ULAF_SALPA ;
DR   A9N514, ULAF_SALPB ;  C0Q6F5, ULAF_SALPC ;  B5BKK6, ULAF_SALPK ;
DR   Q8Z167, ULAF_SALTI ;  Q8ZK85, ULAF_SALTY ;  B2TY70, ULAF_SHIB3 ;
DR   P0C1B9, ULAF_SHIBS ;  Q328K0, ULAF_SHIDS ;  Q0SX87, ULAF_SHIF8 ;
DR   Q83P26, ULAF_SHIFL ;  Q3YUF0, ULAF_SHISS ;
//
ID   5.1.3.5
DE   UDP-arabinose 4-epimerase.
CA   UDP-L-arabinose = UDP-D-xylose.
DR   Q9SA77, ARAE1_ARATH;  Q8H930, ARAE1_ORYSJ;  O64749, ARAE2_ARATH;
DR   Q8H0B6, ARAE2_ORYSJ;  Q9SUN3, ARAE3_ARATH;  Q8H0B2, ARAE3_ORYSJ;
DR   Q9FI17, ARAE4_ARATH;
//
ID   5.1.3.6
DE   UDP-glucuronate 4-epimerase.
AN   UDP glucuronic epimerase.
AN   UDP-galacturonate 4-epimerase.
AN   Uridine diphosphoglucuronate epimerase.
CA   UDP-glucuronate = UDP-D-galacturonate.
DR   Q9M0B6, GAE1_ARATH ;  Q9LPC1, GAE2_ARATH ;  O81312, GAE3_ARATH ;
DR   O22141, GAE4_ARATH ;  Q9STI6, GAE5_ARATH ;  Q9LIS3, GAE6_ARATH ;
//
ID   5.1.3.7
DE   UDP-N-acetylglucosamine 4-epimerase.
AN   UDP-GlcNAc 4-epimerase.
AN   Uridine diphosphoacetylglucosamine epimerase.
CA   UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-galactosamine.
DR   Q8X7P7, GNE_ECO57  ;
//
ID   5.1.3.8
DE   N-acylglucosamine 2-epimerase.
AN   GlcNAc 2-epimerase.
AN   N-acetyl-D-glucosamine 2-epimerase.
CA   N-acyl-D-glucosamine = N-acyl-D-mannosamine.
CC   -!- Requires catalytic amounts of ATP.
DR   Q2KIS1, RENBP_BOVIN;  O18921, RENBP_CANFA;  P51606, RENBP_HUMAN;
DR   P82343, RENBP_MOUSE;  P17560, RENBP_PIG  ;  P51607, RENBP_RAT  ;
//
ID   5.1.3.9
DE   N-acylglucosamine-6-phosphate 2-epimerase.
AN   Acylglucosamine phosphate 2-epimerase.
AN   Acylglucosamine-6-phosphate 2-epimerase.
AN   Acylmannosamine phosphate 2-epimerase.
AN   N-acetylglucosmamine 6-phosphate 2-epimerase.
AN   N-acetylmannosamine-6-phosphate 2-epimerase.
CA   N-acyl-D-glucosamine 6-phosphate = N-acyl-D-mannosamine 6-phosphate.
DR   Q5PG85, NANE1_SALPA;  P60631, NANE1_SALTY;  Q97Q95, NANE1_STRPN;
DR   Q8DPF0, NANE1_STRR6;  Q5PLF1, NANE2_SALPA;  Q8ZLQ7, NANE2_SALTY;
DR   P65520, NANE2_STRPN;  P65521, NANE2_STRR6;  Q8YBP2, NANEK_BRUME;
DR   Q8FWN5, NANEK_BRUSU;  A3N350, NANE_ACTP2 ;  B3GZ03, NANE_ACTP7 ;
DR   B0BSI0, NANE_ACTPJ ;  Q5WK54, NANE_BACSK ;  Q0SMK9, NANE_BORAP ;
DR   O51589, NANE_BORBU ;  B7J2K0, NANE_BORBZ ;  Q660M6, NANE_BORGA ;
DR   Q185B2, NANE_CLOD6 ;  Q0TUP9, NANE_CLOP1 ;  Q8XNZ3, NANE_CLOPE ;
DR   Q0SWI9, NANE_CLOPS ;  A4QH48, NANE_CORGB ;  Q8NMD0, NANE_CORGL ;
DR   A7ZSB6, NANE_ECO24 ;  B7UJV6, NANE_ECO27 ;  B7MBY5, NANE_ECO45 ;
DR   Q8X9G9, NANE_ECO57 ;  B5YSV0, NANE_ECO5E ;  B7NKT4, NANE_ECO7I ;
DR   B7M0T5, NANE_ECO8A ;  C4ZSW1, NANE_ECOBW ;  B1XHJ6, NANE_ECODH ;
DR   A8A533, NANE_ECOHS ;  A1AGB7, NANE_ECOK1 ;  Q0TCP3, NANE_ECOL5 ;
DR   P0A762, NANE_ECOL6 ;  B1IQQ6, NANE_ECOLC ;  P0A761, NANE_ECOLI ;
DR   B7NDK1, NANE_ECOLU ;  B6I1U1, NANE_ECOSE ;  B1LGI8, NANE_ECOSM ;
DR   C5B754, NANE_EDWI9 ;  A4WDW4, NANE_ENT38 ;  Q939I2, NANE_ENTAE ;
DR   Q8KU93, NANE_ENTFA ;  B7LRJ1, NANE_ESCF3 ;  Q8RDN5, NANE_FUSNN ;
DR   Q7VKN0, NANE_HAEDU ;  P71340, NANE_HAEIN ;  B8F667, NANE_HAEPS ;
DR   B5XSS5, NANE_KLEP3 ;  A6TEN5, NANE_KLEP7 ;  Q040Z7, NANE_LACGA ;
DR   Q74HT0, NANE_LACJO ;  Q9CGC2, NANE_LACLA ;  A2RKU2, NANE_LACLM ;
DR   Q02YU5, NANE_LACLS ;  P59441, NANE_LACPL ;  Q38V36, NANE_LACSS ;
DR   Q926V7, NANE_LISIN ;  C1L0D5, NANE_LISMC ;  Q71VW2, NANE_LISMF ;
DR   B8DD13, NANE_LISMH ;  Q8Y3N4, NANE_LISMO ;  A0AMC4, NANE_LISW6 ;
DR   Q2SS69, NANE_MYCCT ;  Q6MT55, NANE_MYCMS ;  Q8EWM9, NANE_MYCPE ;
DR   Q98QJ8, NANE_MYCPU ;  Q8EMP6, NANE_OCEIH ;  Q9L6B4, NANE_PASMU ;
DR   Q03HR3, NANE_PEDPA ;  Q6LPV5, NANE_PHOPR ;  Q6A6A0, NANE_PROAC ;
DR   B4EZY9, NANE_PROMH ;  B5F7J7, NANE_SALA4 ;  A9MNY8, NANE_SALAR ;
DR   A9N831, NANE_SALPB ;  P60668, NANE_SALTI ;  B2U1W1, NANE_SHIB3 ;
DR   Q31W92, NANE_SHIBS ;  Q32BB6, NANE_SHIDS ;  Q0T067, NANE_SHIF8 ;
DR   P59442, NANE_SHIFL ;  Q3YX25, NANE_SHISS ;  A7WXZ6, NANE_STAA1 ;
DR   A6TYA2, NANE_STAA2 ;  Q2FJU6, NANE_STAA3 ;  Q2G157, NANE_STAA8 ;
DR   A5IPI5, NANE_STAA9 ;  Q2YVA8, NANE_STAAB ;  Q5HJ50, NANE_STAAC ;
DR   A6QDV0, NANE_STAAE ;  P65516, NANE_STAAM ;  P65517, NANE_STAAN ;
DR   Q6GJZ8, NANE_STAAR ;  Q6GCF3, NANE_STAAS ;  A8YZE2, NANE_STAAT ;
DR   Q8NYC4, NANE_STAAW ;  B9DIJ5, NANE_STACT ;  Q4L9T7, NANE_STAHJ ;
DR   Q4A094, NANE_STAS1 ;  Q3K3Z4, NANE_STRA1 ;  P65518, NANE_STRA3 ;
DR   P65519, NANE_STRA5 ;  A8AUI0, NANE_STRGC ;  P65522, NANE_STRP1 ;
DR   P0DC68, NANE_STRP3 ;  Q5XDY5, NANE_STRP6 ;  C1C8S3, NANE_STRP7 ;
DR   P65523, NANE_STRP8 ;  Q1JDM7, NANE_STRPB ;  Q1JNJ8, NANE_STRPC ;
DR   Q1JIP7, NANE_STRPD ;  Q1J8K5, NANE_STRPF ;  A2RCG2, NANE_STRPG ;
DR   Q48VD6, NANE_STRPM ;  P0DC69, NANE_STRPQ ;  B5XJP1, NANE_STRPZ ;
DR   C5VXY0, NANE_STRSE ;  P0CB52, NANE_STRSU ;  A3CK30, NANE_STRSV ;
DR   A4VW79, NANE_STRSY ;  B9DVU8, NANE_STRU0 ;  C1CSU8, NANE_STRZT ;
DR   Q31KC5, NANE_SYNE7 ;  Q5N1J0, NANE_SYNP6 ;  Q8DGQ5, NANE_THEEB ;
DR   Q8R7I7, NANE_THETN ;  A5F7B9, NANE_VIBC3 ;  Q9KR62, NANE_VIBCH ;
DR   C3LNA0, NANE_VIBCM ;  Q5E735, NANE_VIBF1 ;  Q8D613, NANE_VIBVU ;
DR   Q7MD32, NANE_VIBVY ;  A7FG95, NANE_YERP3 ;  Q1C5U6, NANE_YERPA ;
DR   B2K948, NANE_YERPB ;  Q8ZCG8, NANE_YERPE ;  Q1CJY8, NANE_YERPN ;
DR   A4TMJ5, NANE_YERPP ;  Q668J7, NANE_YERPS ;  B1JFV9, NANE_YERPY ;
//
ID   5.1.3.10
DE   CDP-paratose 2-epimerase.
AN   CDP-abequose epimerase.
AN   CDP-D-abequose 2-epimerase.
AN   CDP-paratose epimerase.
AN   CDP-tyvelose 2-epimerase.
AN   Cytidine diphosphate paratose-2-epimerase.
AN   Cytidine diphosphoabequose epimerase.
AN   Cytidine diphosphodideoxyglucose epimerase.
AN   Cytidine diphosphoparatose epimerase.
CA   CDP-3,6-dideoxy-D-glucose = CDP-3,6-dideoxy-D-mannose.
CF   NAD.
CC   -!- CDP-paratose (CDP-3,6-dideoxy-D-glucose), is more systematically
CC       called CDP-alpha-3,6-dideoxy-D-ribo-hexose.
CC   -!- CDP-tyvelose (CDP-3,6-dideoxy-D-mannose) is systematically called
CC       CDP-3,6-dideoxy-D-arabino-hexose.
DR   P14169, RFBE_SALTI ;
//
ID   5.1.3.11
DE   Cellobiose epimerase.
CA   Cellobiose = D-glucosyl-D-mannose.
//
ID   5.1.3.12
DE   UDP-glucuronate 5'-epimerase.
AN   UDP-glucuronic acid 5'-epimerase.
AN   UDP-glucuronic acid epimerase.
CA   UDP-glucuronate = UDP-L-iduronate.
CF   NAD.
DR   O54067, LPSL_RHIME ;
//
ID   5.1.3.13
DE   dTDP-4-dehydrorhamnose 3,5-epimerase.
AN   dTDP-4-keto-6-deoxyglucose 3,5-epimerase.
AN   dTDP-L-rhamnose synthetase.
AN   Thymidine diphospho-4-ketorhamnose 3,5-epimerase.
CA   dTDP-4-dehydro-6-deoxy-D-glucose = dTDP-4-dehydro-6-deoxy-L-mannose.
CC   -!- Occurs in a complex with EC 1.1.1.133.
DR   P37745, RMLC_ECOLI ;  O27818, RMLC_METTH ;  A0QSK5, RMLC_MYCS2 ;
DR   O06330, RMLC_MYCTU ;  P37763, RMLC_NEIGO ;  Q9HU21, RMLC_PSEAE ;
DR   P55468, RMLC_RHISN ;  P26394, RMLC_SALTY ;  P37780, RMLC_SHIFL ;
DR   P29783, RMLC_STRGR ;  Q5XCG7, RMLC_STRP6 ;
//
ID   5.1.3.14
DE   UDP-N-acetylglucosamine 2-epimerase.
AN   UDP-GlcNAc-2-epimerase.
AN   Uridine diphosphate-N-acetylglucosamine-2'-epimerase.
AN   Uridine diphospho-N-acetylglucosamine 2'-epimerase.
AN   Uridine diphosphoacetylglucosamine 2'-epimerase.
CA   UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine.
CC   -!- Hydrolyzes the product to UDP and N-acetyl-D-mannosamine.
DR   P58600, EPSC1_RALSO;  P52641, EPSC2_RALSO;  Q7TQ49, GLCNE_CRIGR;
DR   Q9Y223, GLCNE_HUMAN;  Q91WG8, GLCNE_MOUSE;  O35826, GLCNE_RAT  ;
DR   P39131, MNAA_BACSU ;  P52642, RFBC_SALBO ;  Q8XAR8, WECB_ECO57 ;
DR   P27828, WECB_ECOLI ;  Q58899, WECB_METJA ;  Q6LZC4, WECB_METMP ;
DR   Q8Z388, WECB_SALTI ;  Q9L6R5, WECB_SALTY ;  Q8ZAE3, WECB_YERPE ;
DR   Q9X0C4, Y1034_THEMA;  P45360, Y2874_CLOAB;
//
ID   5.1.3.15
DE   Glucose-6-phosphate 1-epimerase.
CA   Alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate.
DR   Q40784, AAPC_CENCI ;  P44160, Y1317_HAEIN;  P39173, YEAD_ECOLI ;
DR   Q03161, YMY9_YEAST ;
//
ID   5.1.3.16
DE   UDP-glucosamine 4-epimerase.
CA   UDP-glucosamine = UDP-galactosamine.
//
ID   5.1.3.17
DE   Heparosan-N-sulfate-glucuronate 5-epimerase.
CA   Heparosan-N-sulfate D-glucuronate = heparosan-N-sulfate L-iduronate.
CC   -!- Acts on D-glucuronosyl residues adjacent to sulfated D-glucosamine
CC       units in the heparin precursor.
CC   -!- Not identical with EC 5.1.3.19.
//
ID   5.1.3.18
DE   GDP-mannose 3,5-epimerase.
CA   GDP-mannose = GDP-L-galactose.
DR   A2Z7B3, GME1_ORYSI ;  A3C4S4, GME1_ORYSJ ;  Q2R1V8, GME2_ORYSJ ;
DR   Q93VR3, GME_ARATH  ;
//
ID   5.1.3.19
DE   Chondroitin-glucuronate 5-epimerase.
AN   Dermatan-sulfate 5-epimerase.
AN   Polyglucuronate 5-epimerase.
CA   Chondroitin D-glucuronate = dermatan L-iduronate.
CC   -!- Not identical with EC 5.1.3.17.
DR   P0C2H4, DSE_BOVIN  ;  Q9UL01, DSE_HUMAN  ;  Q8BLI4, DSE_MOUSE  ;
//
ID   5.1.3.20
DE   ADP-glyceromanno-heptose 6-epimerase.
AN   ADP-L-glycero-D-manno-heptose 6-epimerase.
CA   ADP-D-glycero-D-manno-heptose = ADP-L-glycero-D-manno-heptose.
CF   NAD.
DR   A3N308, HLDD_ACTP2 ;  B3GYT6, HLDD_ACTP7 ;  B0BSD7, HLDD_ACTPJ ;
DR   A6VLD2, HLDD_ACTSZ ;  A0KQV3, HLDD_AERHH ;  A4SHC0, HLDD_AERS4 ;
DR   Q0A4T8, HLDD_ALHEH ;  Q5P2S1, HLDD_AROAE ;  A1KBH4, HLDD_AZOSB ;
DR   Q2L2R8, HLDD_BORA1 ;  Q7WGU9, HLDD_BORBR ;  Q7W609, HLDD_BORPA ;
DR   A9IJJ7, HLDD_BORPD ;  Q7VZF5, HLDD_BORPE ;  C0QZ84, HLDD_BRAHW ;
DR   B1YV41, HLDD_BURA4 ;  Q1BY20, HLDD_BURCA ;  B1JXS7, HLDD_BURCC ;
DR   A0K5M9, HLDD_BURCH ;  B4EB34, HLDD_BURCJ ;  Q0BH85, HLDD_BURCM ;
DR   A9ADU8, HLDD_BURM1 ;  A3MHP7, HLDD_BURM7 ;  A2S4R1, HLDD_BURM9 ;
DR   Q62M34, HLDD_BURMA ;  A1V6L4, HLDD_BURMS ;  A3NXW3, HLDD_BURP0 ;
DR   Q3JPY8, HLDD_BURP1 ;  A3NC24, HLDD_BURP6 ;  B2JF12, HLDD_BURP8 ;
DR   B2T625, HLDD_BURPP ;  Q9WWX6, HLDD_BURPS ;  Q39IF3, HLDD_BURS3 ;
DR   Q2SY18, HLDD_BURTA ;  A4JCI2, HLDD_BURVG ;  Q13VD0, HLDD_BURXL ;
DR   Q1R1N5, HLDD_CHRSD ;  Q7NTL6, HLDD_CHRVO ;  A8ARK8, HLDD_CITK8 ;
DR   Q0KDH0, HLDD_CUPNH ;  Q46Y59, HLDD_CUPPJ ;  B3R3C0, HLDD_CUPTR ;
DR   Q47GJ3, HLDD_DECAR ;  Q72ET7, HLDD_DESVH ;  A1VGB0, HLDD_DESVV ;
DR   A7ZTH2, HLDD_ECO24 ;  B7ULH4, HLDD_ECO27 ;  B7MFI2, HLDD_ECO45 ;
DR   B7L745, HLDD_ECO55 ;  P67911, HLDD_ECO57 ;  B5YWC0, HLDD_ECO5E ;
DR   B7NPC7, HLDD_ECO7I ;  B7N1S3, HLDD_ECO81 ;  B7M4A5, HLDD_ECO8A ;
DR   C4ZXL1, HLDD_ECOBW ;  B1X953, HLDD_ECODH ;  A8A683, HLDD_ECOHS ;
DR   A1AHF5, HLDD_ECOK1 ;  Q0TBI8, HLDD_ECOL5 ;  Q8FCA0, HLDD_ECOL6 ;
DR   B1IZH2, HLDD_ECOLC ;  P67910, HLDD_ECOLI ;  B7NES6, HLDD_ECOLU ;
DR   B6I3J9, HLDD_ECOSE ;  B1LK58, HLDD_ECOSM ;  Q1R4X2, HLDD_ECOUT ;
DR   C5BB97, HLDD_EDWI9 ;  A4W527, HLDD_ENT38 ;  A7MQ91, HLDD_ENTS8 ;
DR   Q6DAT7, HLDD_ERWCT ;  B2VL47, HLDD_ERWT9 ;  B7LVH8, HLDD_ESCF3 ;
DR   Q8RIA5, HLDD_FUSNN ;  Q7VKK8, HLDD_HAEDU ;  Q4QLI0, HLDD_HAEI8 ;
DR   A5UIN9, HLDD_HAEIG ;  P45048, HLDD_HAEIN ;  B8F727, HLDD_HAEPS ;
DR   Q0I569, HLDD_HAES1 ;  B0UWU3, HLDD_HAES2 ;  C4K8I6, HLDD_HAMD5 ;
DR   B5XTI2, HLDD_KLEP3 ;  A6TFL4, HLDD_KLEP7 ;  Q9XCA1, HLDD_KLEPN ;
DR   Q65WA7, HLDD_MANSM ;  A1TYR6, HLDD_MARAV ;  Q5F9J0, HLDD_NEIG1 ;
DR   Q51061, HLDD_NEIGO ;  A9M3Q7, HLDD_NEIM0 ;  Q9JQX8, HLDD_NEIMA ;
DR   Q9K002, HLDD_NEIMB ;  A1KT78, HLDD_NEIMF ;  Q3J7X9, HLDD_NITOC ;
DR   Q9CL97, HLDD_PASMU ;  C6DIA9, HLDD_PECCP ;  Q3A8K5, HLDD_PELCD ;
DR   Q7MY46, HLDD_PHOLL ;  A1VR25, HLDD_POLNA ;  B1XVP6, HLDD_POLNS ;
DR   Q12CM2, HLDD_POLSJ ;  B4F132, HLDD_PROMH ;  A6V291, HLDD_PSEA7 ;
DR   Q02QH1, HLDD_PSEAB ;  Q9HYQ8, HLDD_PSEAE ;  A1SRT6, HLDD_PSYIN ;
DR   Q1LQG2, HLDD_RALME ;  B2U894, HLDD_RALPJ ;  Q8Y0X8, HLDD_RALSO ;
DR   Q98I52, HLDD_RHILO ;  Q21Y60, HLDD_RHOFD ;  B5EXC5, HLDD_SALA4 ;
DR   A9MKQ6, HLDD_SALAR ;  Q57IC3, HLDD_SALCH ;  B5FLI8, HLDD_SALDC ;
DR   B5R5E3, HLDD_SALEP ;  B5RGG8, HLDD_SALG2 ;  B4T9A3, HLDD_SALHS ;
DR   B4SXC1, HLDD_SALNS ;  Q5PC05, HLDD_SALPA ;  A9MVL2, HLDD_SALPB ;
DR   C0Q1V2, HLDD_SALPC ;  B5BHZ3, HLDD_SALPK ;  B4TZW1, HLDD_SALSV ;
DR   P67913, HLDD_SALTI ;  P67912, HLDD_SALTY ;  A8GLC8, HLDD_SERP5 ;
DR   Q07W60, HLDD_SHEFN ;  A3QJB2, HLDD_SHELP ;  B8CVJ3, HLDD_SHEPW ;
DR   B2U5D7, HLDD_SHIB3 ;  Q31V04, HLDD_SHIBS ;  Q329N6, HLDD_SHIDS ;
DR   Q0SYE8, HLDD_SHIF8 ;  Q83PP2, HLDD_SHIFL ;  Q3YVY3, HLDD_SHISS ;
DR   Q2NQV7, HLDD_SODGM ;  Q31FG4, HLDD_THICR ;  Q3SK74, HLDD_THIDA ;
DR   A5F3Z4, HLDD_VIBC3 ;  Q06963, HLDD_VIBCH ;  C3LQK1, HLDD_VIBCM ;
DR   Q5E8J9, HLDD_VIBF1 ;  B5FFS9, HLDD_VIBFM ;  A7MSM1, HLDD_VIBHB ;
DR   Q87T56, HLDD_VIBPA ;  Q8DE09, HLDD_VIBVU ;  Q7MPN6, HLDD_VIBVY ;
DR   A1JHX6, HLDD_YERE8 ;  A7FCU3, HLDD_YERP3 ;  Q1C276, HLDD_YERPA ;
DR   B2JYP2, HLDD_YERPB ;  Q8ZJN4, HLDD_YERPE ;  A9R683, HLDD_YERPG ;
DR   Q1CD11, HLDD_YERPN ;  A4TSC8, HLDD_YERPP ;  Q66GC7, HLDD_YERPS ;
DR   B1JQW4, HLDD_YERPY ;
//
ID   5.1.3.21
DE   Maltose epimerase.
CA   Alpha-maltose = beta-maltose.
CC   -!- The enzyme catalyzes the interconversion of alpha and beta anomers of
CC       maltose more effectively than those of disaccharides such as lactose
CC       and cellobiose.
//
ID   5.1.3.22
DE   L-ribulose-5-phosphate 3-epimerase.
AN   L-xylulose 5-phosphate 3-epimerase.
CA   L-ribulose 5-phosphate = L-xylulose 5-phosphate.
CC   -!- Along with EC 4.1.1.85, this enzyme is involved in a pathway for the
CC       utilization of L-ascorbate by Escherichia coli.
DR   P37679, SGBU_ECOLI ;  A7ZV68, ULAE_ECO24 ;  B7UQK6, ULAE_ECO27 ;
DR   B7MLK2, ULAE_ECO45 ;  B7LCQ7, ULAE_ECO55 ;  Q8XDI5, ULAE_ECO57 ;
DR   B5Z2K3, ULAE_ECO5E ;  B7NTQ3, ULAE_ECO7I ;  B7M9F9, ULAE_ECO8A ;
DR   C4ZR74, ULAE_ECOBW ;  B1XDU8, ULAE_ECODH ;  A8A7U3, ULAE_ECOHS ;
DR   A1AJA2, ULAE_ECOK1 ;  Q0T9J6, ULAE_ECOL5 ;  Q8FAI7, ULAE_ECOL6 ;
DR   B1IT09, ULAE_ECOLC ;  P39305, ULAE_ECOLI ;  B7NGD1, ULAE_ECOLU ;
DR   B6I2A2, ULAE_ECOSE ;  B1LQL7, ULAE_ECOSM ;  Q1R363, ULAE_ECOUT ;
DR   B7LLX9, ULAE_ESCF3 ;  P75294, ULAE_MYCPN ;  B5F3B3, ULAE_SALA4 ;
DR   Q57GJ5, ULAE_SALCH ;  B5FS98, ULAE_SALDC ;  B5R0R4, ULAE_SALEP ;
DR   B5R9E4, ULAE_SALG2 ;  B4TFD1, ULAE_SALHS ;  Q5PJ62, ULAE_SALPA ;
DR   A9N513, ULAE_SALPB ;  C0Q6F4, ULAE_SALPC ;  B5BKK5, ULAE_SALPK ;
DR   B4TT29, ULAE_SALSV ;  Q8Z168, ULAE_SALTI ;  Q8ZK86, ULAE_SALTY ;
DR   B2TY69, ULAE_SHIB3 ;  Q31TC8, ULAE_SHIBS ;  P0C1B2, ULAE_SHIDS ;
DR   Q0SX88, ULAE_SHIF8 ;  Q83II8, ULAE_SHIFL ;  Q3YUF1, ULAE_SHISS ;
//
ID   5.1.3.23
DE   UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase.
AN   2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronic acid 2-epimerase.
AN   UDP-alpha-D-GlcNAc3NAcA 2-epimerase.
AN   UDP-GlcNAc3NAcA 2-epimerase.
CA   UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate = UDP-2,3-
CA   diacetamido-2,3-dideoxy-alpha-D-mannuronate.
CC   -!- Participates in the biosynthetic pathway for UDP-alpha-D-ManNAc3NAcA
CC       (UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronic acid),
CC       an important precursor of the B-band lipopolysaccharide of
CC       Pseudomonas aeroginosa serotype O5 and of the band-A trisaccharide of
CC       Bordetella pertussis, both important respiratory pathogens.
CC   -!- Highly specific as UDP-alpha-D-GlcNAc, UDP-alpha-D-GlcNAcA (UDP-2-
CC       acetamido-2-deoxy-alpha-D-glucuronic acid) and UDP-alpha-D-GlcNAc3NAc
CC       (UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucose) cannot act as
CC       substrates.
//
ID   5.1.3.n1
DE   Sialic acid epimerase.
AN   Alpha-N-acetylneuraminic acid epimerase.
AN   Sialic acid mutarotase.
CA   N-acetyl-alpha-neuraminate = N-acetyl-beta-neuraminate.
DR   Q8CVR2, NANM1_ECOL6;  Q8CVG5, NANM2_ECOL6;  Q2YK69, NANM_BRUA2 ;
DR   Q577K1, NANM_BRUAB ;  Q8YBP3, NANM_BRUME ;  A5VU94, NANM_BRUO2 ;
DR   A9WYA0, NANM_BRUSI ;  A7ZVK8, NANM_ECO24 ;  Q8X554, NANM_ECO57 ;
DR   A8A834, NANM_ECOHS ;  A1AJH6, NANM_ECOK1 ;  Q0T900, NANM_ECOL5 ;
DR   P39371, NANM_ECOLI ;  Q1R2K5, NANM_ECOUT ;  Q4QP39, NANM_HAEI8 ;
DR   A5UB03, NANM_HAEIE ;  A5UFV3, NANM_HAEIG ;  P44544, NANM_HAEIN ;
DR   Q9CKB7, NANM_PASMU ;  A9MH34, NANM_SALAR ;  Q57QM5, NANM_SALCH ;
DR   B5R066, NANM_SALEP ;  B4T2W1, NANM_SALNS ;  A9N6P2, NANM_SALPB ;
DR   B4TSP0, NANM_SALSV ;  Q8Z7N0, NANM_SALTI ;  Q8ZQ34, NANM_SALTY ;
DR   Q31T32, NANM_SHIBS ;  Q0SXL5, NANM_SHIF8 ;  Q83IN1, NANM_SHIFL ;
DR   Q3YU63, NANM_SHISS ;  A5F7B3, NANM_VIBC3 ;  Q9KR69, NANM_VIBCH ;
DR   Q7MD39, NANM_VIBVY ;  A1JMV0, NANM_YERE8 ;  A7FJ01, NANM_YERP3 ;
DR   Q1C8L8, NANM_YERPA ;  Q7CI10, NANM_YERPE ;  Q1CHD7, NANM_YERPN ;
DR   A4TK48, NANM_YERPP ;  Q66BP2, NANM_YERPS ;
//
ID   5.1.3.n2
DE   L-fucose mutarotase.
AN   Fucose 1-epimerase.
AN   Type-2 mutarotase.
CA   Alpha-L-fucose = beta-L-fucose.
DR   A3N2Y4, FUCM_ACTP2 ;  B3H2T2, FUCM_ACTP7 ;  B0BSB3, FUCM_ACTPJ ;
DR   Q0P563, FUCM_BOVIN ;  A8AP17, FUCM_CITK8 ;  Q7ZZ03, FUCM_DANRE ;
DR   A7ZQP8, FUCM_ECO24 ;  B7UHM0, FUCM_ECO27 ;  B7MLC5, FUCM_ECO45 ;
DR   B7LEY4, FUCM_ECO55 ;  P0AEP0, FUCM_ECO57 ;  B5Z4C4, FUCM_ECO5E ;
DR   B7NVV2, FUCM_ECO7I ;  B7MZA0, FUCM_ECO81 ;  B7LXM0, FUCM_ECO8A ;
DR   C4ZZV9, FUCM_ECOBW ;  B1XDL3, FUCM_ECODH ;  A8A3T9, FUCM_ECOHS ;
DR   A1AEZ1, FUCM_ECOK1 ;  Q0TE55, FUCM_ECOL5 ;  P0AEN9, FUCM_ECOL6 ;
DR   B1IU37, FUCM_ECOLC ;  P0AEN8, FUCM_ECOLI ;  B7N738, FUCM_ECOLU ;
DR   B6I6K2, FUCM_ECOSE ;  B1LQZ8, FUCM_ECOSM ;  Q1R7N6, FUCM_ECOUT ;
DR   Q4QMI4, FUCM_HAEI8 ;  A5UAS6, FUCM_HAEIE ;  A5UHL6, FUCM_HAEIG ;
DR   P44778, FUCM_HAEIN ;  B8F6Y2, FUCM_HAEPS ;  Q0I5M5, FUCM_HAES1 ;
DR   B0US22, FUCM_HAES2 ;  A2VDF0, FUCM_HUMAN ;  B5XUY2, FUCM_KLEP3 ;
DR   A6TD85, FUCM_KLEP7 ;  Q8R2K1, FUCM_MOUSE ;  B5F4S5, FUCM_SALA4 ;
DR   A9MSA4, FUCM_SALAR ;  Q57KD8, FUCM_SALCH ;  B5FTY3, FUCM_SALDC ;
DR   B5QWR2, FUCM_SALEP ;  B5RDV6, FUCM_SALG2 ;  B4TGN5, FUCM_SALHS ;
DR   B4T4X3, FUCM_SALNS ;  Q5PEK7, FUCM_SALPA ;  A9N2J4, FUCM_SALPB ;
DR   C0PXG7, FUCM_SALPC ;  B5BF33, FUCM_SALPK ;  B4TUJ9, FUCM_SALSV ;
DR   Q8Z427, FUCM_SALTI ;  Q8ZMC4, FUCM_SALTY ;  B2TZD0, FUCM_SHIB3 ;
DR   Q31XI7, FUCM_SHIBS ;  Q32CB4, FUCM_SHIDS ;  Q0T156, FUCM_SHIF8 ;
DR   Q83QC7, FUCM_SHIFL ;  Q3YY53, FUCM_SHISS ;
//
ID   5.1.3.n3
DE   L-rhamnose mutarotase.
AN   Rhamnose 1-epimerase.
AN   Type-3 mutarotase.
CA   Alpha-L-rhamnose = beta-L-rhamnose.
DR   A5G2T9, RHAM_ACICJ ;  A9CFA8, RHAM_AGRT5 ;  B9K2Z2, RHAM_AGRVS ;
DR   Q5WL37, RHAM_BACSK ;  O05263, RHAM_BACSU ;  Q8A044, RHAM_BACTN ;
DR   A6KWR4, RHAM_BACV8 ;  B1YMY7, RHAM_BURA4 ;  Q1BGJ2, RHAM_BURCA ;
DR   B1KAV4, RHAM_BURCC ;  A0KDV0, RHAM_BURCH ;  Q0BA68, RHAM_BURCM ;
DR   B2JLI5, RHAM_BURP8 ;  B2TFM4, RHAM_BURPP ;  Q13LW8, RHAM_BURXL ;
DR   A8AL34, RHAM_CITK8 ;  A6LQL0, RHAM_CLOB8 ;  A9KN28, RHAM_CLOPH ;
DR   A8LS71, RHAM_DINSH ;  A7ZUB2, RHAM_ECO24 ;  B7UNM2, RHAM_ECO27 ;
DR   B7MI33, RHAM_ECO45 ;  B7L9F7, RHAM_ECO55 ;  Q8X8A2, RHAM_ECO57 ;
DR   B5YZ38, RHAM_ECO5E ;  B7NUA7, RHAM_ECO7I ;  B7MQZ1, RHAM_ECO81 ;
DR   B7M6V3, RHAM_ECO8A ;  C5A069, RHAM_ECOBW ;  B1XB68, RHAM_ECODH ;
DR   A8A704, RHAM_ECOHS ;  A1AI78, RHAM_ECOK1 ;  Q0TAG2, RHAM_ECOL5 ;
DR   Q8FBE2, RHAM_ECOL6 ;  B1IVH7, RHAM_ECOLC ;  P32156, RHAM_ECOLI ;
DR   B7NFJ9, RHAM_ECOLU ;  B6I4P3, RHAM_ECOSE ;  B1LMU1, RHAM_ECOSM ;
DR   Q1R418, RHAM_ECOUT ;  A4WGA0, RHAM_ENT38 ;  Q838L0, RHAM_ENTFA ;
DR   A7ML65, RHAM_ENTS8 ;  Q6DA26, RHAM_ERWCT ;  B7LVE3, RHAM_ESCF3 ;
DR   A5FC30, RHAM_FLAJ1 ;  Q28P47, RHAM_JANSC ;  B5XZ60, RHAM_KLEP3 ;
DR   A6TGA0, RHAM_KLEP7 ;  Q88S50, RHAM_LACPL ;  Q1WRE3, RHAM_LACS1 ;
DR   B1Y3E6, RHAM_LEPCP ;  Q926R3, RHAM_LISIN ;  Q71VR6, RHAM_LISMF ;
DR   Q8Y3I9, RHAM_LISMO ;  Q65Q29, RHAM_MANSM ;  Q8ESX3, RHAM_OCEIH ;
DR   A6X4W8, RHAM_OCHA4 ;  B1ZR75, RHAM_OPITP ;  C6DJR0, RHAM_PECCP ;
DR   Q2K0S6, RHAM_RHIEC ;  Q1M5X7, RHAM_RHIL3 ;  Q98B72, RHAM_RHILO ;
DR   Q7BSH1, RHAM_RHILT ;  Q92S07, RHAM_RHIME ;  C3MFZ6, RHAM_RHISN ;
DR   Q164K6, RHAM_ROSDO ;  B5F0M4, RHAM_SALA4 ;  A9MI70, RHAM_SALAR ;
DR   Q57HH3, RHAM_SALCH ;  B5FP36, RHAM_SALDC ;  B5QWX9, RHAM_SALEP ;
DR   B5RFC8, RHAM_SALG2 ;  B4TBX8, RHAM_SALHS ;  B4SZY8, RHAM_SALNS ;
DR   Q5PKG7, RHAM_SALPA ;  A9MZC2, RHAM_SALPB ;  B5BJG3, RHAM_SALPK ;
DR   B4TPQ4, RHAM_SALSV ;  Q8XF56, RHAM_SALTI ;  Q7CPC4, RHAM_SALTY ;
DR   B2TVP4, RHAM_SHIB3 ;  Q31U88, RHAM_SHIBS ;  Q32A67, RHAM_SHIDS ;
DR   Q0SZ91, RHAM_SHIF8 ;  Q83IU5, RHAM_SHIFL ;  Q3YV75, RHAM_SHISS ;
DR   A6U608, RHAM_SINMW ;  C4LCV3, RHAM_TOLAT ;  A1WJR4, RHAM_VEREI ;
DR   A7FN85, RHAM_YERP3 ;  Q1C0V2, RHAM_YERPA ;  B2K1V8, RHAM_YERPB ;
DR   Q0WJY2, RHAM_YERPE ;  A9QYS5, RHAM_YERPG ;  Q1CEA9, RHAM_YERPN ;
DR   A4TRT4, RHAM_YERPP ;  Q66FF7, RHAM_YERPS ;  B1JND2, RHAM_YERPY ;
//
ID   5.1.99.1
DE   Methylmalonyl-CoA epimerase.
AN   2-methyl-3-oxopropanoyl-CoA 2-epimerase.
AN   DL-methylmalonyl-CoA racemase.
AN   Methylmalonyl coenzyme A racemase.
AN   Methylmalonyl-CoA racemase.
CA   (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA.
DR   Q2KIZ3, MCEE_BOVIN ;  Q553V2, MCEE_DICDI ;  Q96PE7, MCEE_HUMAN ;
DR   Q9D1I5, MCEE_MOUSE ;
//
ID   5.1.99.2
DE   16-hydroxysteroid epimerase.
CA   16-alpha-hydroxysteroid = 16-beta-hydroxysteroid.
//
ID   5.1.99.3
DE   Allantoin racemase.
CA   (S)(+)-allantoin = (R)(-)-allantoin.
//
ID   5.1.99.4
DE   Alpha-methylacyl-CoA racemase.
CA   (2S)-2-methylacyl-CoA = (2R)-2-methylacyl-CoA.
CC   -!- Alpha-methyl-branched acyl-CoA derivatives with chain lengths of more
CC       than C(10) are substrates.
CC   -!- Also active toward some aromatic compounds (e.g. ibuprofen) and bile
CC       acid intermediates, such as trihydroxycoprostanoyl-CoA.
CC   -!- Not active toward free acids.
DR   Q9UHK6, AMACR_HUMAN;  O09174, AMACR_MOUSE;  P70473, AMACR_RAT  ;
//
ID   5.1.99.5
DE   Hydantoin racemase.
AN   5'-monosubstituted-hydantoin racemase.
CA   D-5-monosubstituted hydantoin = L-5-monosubstituted hydantoin.
CC   -!- This enzyme, along with EC 3.5.1.77, EC 3.5.1.87 and EC 3.5.2.2,
CC       forms part of the reaction cascade known as the 'hydantoinase
CC       process', which allows the total conversion of D,L-5-monosubstituted
CC       hydantoins into optically pure D- or L-amino acids.
CC   -!- The enzyme from Pseudomonas sp. (HyuE) has a preference for
CC       hydantoins with aliphatic substituents, e.g. D- and L-5-
CC       (2-methylthioethyl)hydantoin, whereas that from Arthrobacter
CC       aurescens shows highest activity with arylalkyl substituents,
CC       especially 5-benzylhydantoin, at the 5-position.
CC   -!- In the enzyme from Sinorhizobium meliloti, Cys-76 is responsible for
CC       recognition and proton retrieval of D-isomers, while Cys-181 is
CC       responsible for L-isomer recognition and racemization.
DR   Q00924, HYUE_PSESN ;
//
ID   5.2.1.1
DE   Maleate isomerase.
CA   Maleate = fumarate.
//
ID   5.2.1.2
DE   Maleylacetoacetate isomerase.
AN   Maleylacetone isomerase.
CA   4-maleylacetoacetate = 4-fumarylacetoacetate.
CC   -!- Also acts on maleylpyruvate.
DR   Q9VHD3, MAAI1_DROME;  Q9VHD2, MAAI2_DROME;  Q18938, MAAI_CAEEL ;
DR   Q54YN2, MAAI_DICDI ;  O43123, MAAI_EMENI ;  O43708, MAAI_HUMAN ;
DR   Q9WVL0, MAAI_MOUSE ;  P57109, MAAI_PSEAE ;  P57113, MAAI_RAT   ;
DR   Q9X4F7, MAAI_RHIME ;  Q9KSB2, MAAI_VIBCH ;
//
ID   5.2.1.3
DE   Retinal isomerase.
AN   Retinene isomerase.
AN   Retinoid isomerase.
CA   All-trans-retinal = 11-cis-retinal.
CC   -!- Light shifts the reaction toward the cis-isomer.
//
ID   5.2.1.4
DE   Maleylpyruvate isomerase.
CA   3-maleylpyruvate = 3-fumarylpyruvate.
DR   P80580, MHBI_KLEPN ;
//
ID   5.2.1.5
DE   Linoleate isomerase.
CA   9-cis,12-cis-octadecadienoate = 9-cis,11-trans-octadecadienoate.
//
ID   5.2.1.6
DE   Furylfuramide isomerase.
CA   (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide = (Z)-2-(2-furyl)-3-
CA   (5-nitro-2-furyl)acrylamide.
CF   NAD.
//
ID   5.2.1.7
DE   Retinol isomerase.
AN   All-trans-retinol isomerase.
CA   All-trans-retinol = 11-cis-retinol.
CC   -!- Converts all-trans-retinol to 11-cis-retinol in the dark, thus
CC       reversing the effect of EC 5.2.1.3.
DR   Q9YI25, RPE65_AMBTI;  Q28175, RPE65_BOVIN;  Q9TVB8, RPE65_CANFA;
DR   Q9YGX2, RPE65_CHICK;  Q9XT71, RPE65_CHLAE;  Q8AXN9, RPE65_CYNPY;
DR   Q16518, RPE65_HUMAN;  Q91ZQ5, RPE65_MOUSE;  O70276, RPE65_RAT  ;
//
ID   5.2.1.8
DE   Peptidylprolyl isomerase.
AN   Cyclophilin.
AN   Peptidyl-prolyl cis-trans isomerase.
AN   Peptidylprolyl cis-trans isomerase.
AN   PPIase.
AN   Rotamase.
CA   Peptidylproline (omega=180) = peptidylproline (omega=0).
CC   -!- The first type of this enzyme found proved to be the protein
CC       cyclophilin, which binds the immunosuppressant cyclosporin A.
CC   -!- Other distinct families of the enzyme exist, one being FK-506 binding
CC       proteins (FKBP) and another that includes parvulin from Escherichia
CC       coli.
CC   -!- The three families are structurally unrelated and can be
CC       distinguished by being inhibited by cyclosporin A, FK-506 and
CC       5-hydroxy-1,4-naphthoquinone, respectively.
PR   PROSITE; PDOC00154;
PR   PROSITE; PDOC00426;
PR   PROSITE; PDOC00840;
DR   Q5XAQ1, BPPI_STRP6 ;  P34790, CP18C_ARATH;  Q42406, CP18D_ARATH;
DR   Q38900, CP19A_ARATH;  Q9SKQ0, CP19B_ARATH;  Q38867, CP19C_ARATH;
DR   Q8LDP4, CP19D_ARATH;  Q9SP02, CP20A_ARATH;  Q9ASS6, CP20B_ARATH;
DR   P34791, CP20C_ARATH;  Q94A16, CP21C_ARATH;  Q75A74, CWC27_ASHGO;
DR   Q4WE62, CWC27_ASPFU;  Q17QX9, CWC27_BOVIN;  P0CP93, CWC27_CRYNB;
DR   P0CP92, CWC27_CRYNJ;  Q7ZW86, CWC27_DANRE;  Q6BWH6, CWC27_DEBHA;
DR   Q5AUG9, CWC27_EMENI;  Q4IPB3, CWC27_GIBZE;  Q6UX04, CWC27_HUMAN;
DR   Q4R713, CWC27_MACFA;  Q3TKY6, CWC27_MOUSE;  Q7SBX8, CWC27_NEUCR;
DR   Q5R7W3, CWC27_PONAB;  Q5XIB2, CWC27_RAT  ;  P0C1J2, CWC27_RHIOR;
DR   Q4P7H2, CWC27_USTMA;  Q6GLX7, CWC27_XENLA;  Q6CGK4, CWC27_YARLI;
DR   Q02770, CWC27_YEAST;  P52017, CYP10_CAEEL;  P52018, CYP11_CAEEL;
DR   P0C1I9, CYP11_RHIOR;  P0C1J0, CYP15_RHIOR;  Q27450, CYP1_BRUMA ;
DR   P52009, CYP1_CAEEL ;  Q8W171, CYP1_SOYBN ;  P52010, CYP2_CAEEL ;
DR   P82869, CYP37_ARATH;  Q9SSA5, CYP38_ARATH;  P52011, CYP3_CAEEL ;
DR   Q9C566, CYP40_ARATH;  P52012, CYP4_CAEEL ;  P52013, CYP5_CAEEL ;
DR   P0C1I7, CYP5_RHIOR ;  P52014, CYP6_CAEEL ;  P0C1I8, CYP6_RHIOR ;
DR   P52015, CYP7_CAEEL ;  O42941, CYP7_SCHPO ;  P47103, CYP7_YEAST ;
DR   P52016, CYP8_CAEEL ;  P53728, CYP8_YEAST ;  A8X8D0, CYP9_CAEBR ;
DR   Q09637, CYP9_CAEEL ;  O74942, CYP9_SCHPO ;  Q41651, CYPB_VICFA ;
DR   P23285, CYPB_YEAST ;  P25719, CYPC_YEAST ;  P35176, CYPD_YEAST ;
DR   Q9NI62, CYPE_DICDI ;  P34887, CYPH_ALLCE ;  P81531, CYPH_BETPN ;
DR   P24525, CYPH_BRANA ;  Q39613, CYPH_CATRO ;  Q8SRE1, CYPH_ENCCU ;
DR   O49886, CYPH_LUPLU ;  P21569, CYPH_MAIZE ;  P10255, CYPH_NEUCR ;
DR   P18253, CYPH_SCHPO ;  P21568, CYPH_SOLLC ;  O00060, CYPH_UROFA ;
DR   P14832, CYPH_YEAST ;  P28517, CYPR_CALVI ;  P15425, CYPR_DROME ;
DR   P25334, CYPR_YEAST ;  P35627, CYPX_USEUD ;  P22696, ESS1_YEAST ;
DR   Q2HJ89, FKB10_BOVIN;  Q96AY3, FKB10_HUMAN;  Q61576, FKB10_MOUSE;
DR   Q2YDL5, FKB11_BOVIN;  Q9NYL4, FKB11_HUMAN;  Q9D1M7, FKB11_MOUSE;
DR   Q8LGG0, FKB12_ARATH;  P48375, FKB12_DROME;  O04287, FKB12_VICFA;
DR   Q9NWM8, FKB14_HUMAN;  P59024, FKB14_MOUSE;  Q5R941, FKB14_PONAB;
DR   Q41649, FKB15_VICFA;  Q4WLV6, FKB1A_ASPFU;  P18203, FKB1A_BOVIN;
DR   Q6KBA8, FKB1A_EMENI;  P62942, FKB1A_HUMAN;  P26883, FKB1A_MOUSE;
DR   P20080, FKB1A_NEUCR;  P62943, FKB1A_RABIT;  Q62658, FKB1A_RAT  ;
DR   O42123, FKB1A_XENLA;  Q4W9R2, FKB1B_ASPFU;  P68107, FKB1B_BOVIN;
DR   Q5AXD5, FKB1B_EMENI;  P68106, FKB1B_HUMAN;  Q9Z2I2, FKB1B_MOUSE;
DR   Q6M981, FKB1B_NEUCR;  Q8HYX6, FKB1B_RABIT;  P97534, FKB1B_RAT  ;
DR   Q38935, FKB21_ARATH;  Q38936, FKB22_ARATH;  P0C1J4, FKB2A_RHIOR;
DR   P0C1J5, FKB2B_RHIOR;  P54397, FKB39_DROME;  Q9LDC0, FKB42_ARATH;
DR   Q9VL78, FKB59_DROME;  Q38931, FKB70_ARATH;  P81104, FKB70_PINPS;
DR   Q43207, FKB70_WHEAT;  O08437, FKBA_AERHY ;  P57599, FKBA_BUCAI ;
DR   Q8K943, FKBA_BUCAP ;  Q89A61, FKBA_BUCBP ;  P65765, FKBA_ECO57 ;
DR   P65764, FKBA_ECOL6 ;  P45523, FKBA_ECOLI ;  Q9JYI8, FKBA_NEIMB ;
DR   P0A9L3, FKBB_ECOLI ;  P0A9L4, FKBB_SHIFL ;  Q9LM71, FKBP1_ARATH;
DR   Q554J3, FKBP1_DICDI;  Q57726, FKBP1_METJA;  P0C1J3, FKBP1_RHIOR;
DR   O22870, FKBP2_ARATH;  Q4WHX4, FKBP2_ASPFU;  Q2UPT7, FKBP2_ASPOR;
DR   Q32PA9, FKBP2_BOVIN;  Q6FSC1, FKBP2_CANGA;  P0CP97, FKBP2_CRYNB;
DR   P0CP96, FKBP2_CRYNJ;  Q6BP84, FKBP2_DEBHA;  Q54SR7, FKBP2_DICDI;
DR   Q5ATN7, FKBP2_EMENI;  Q4IN00, FKBP2_GIBZE;  P26885, FKBP2_HUMAN;
DR   Q6CUZ8, FKBP2_KLULA;  Q58235, FKBP2_METJA;  P45878, FKBP2_MOUSE;
DR   O60046, FKBP2_NEUCR;  Q86ZF2, FKBP2_PODAS;  P83061, FKBP2_SPIOL;
DR   Q6CGG3, FKBP2_YARLI;  P32472, FKBP2_YEAST;  Q9SCY2, FKBP3_ARATH;
DR   Q756V1, FKBP3_ASHGO;  P26884, FKBP3_BOVIN;  Q59VR3, FKBP3_CANAL;
DR   Q6FKH7, FKBP3_CANGA;  Q6BSE7, FKBP3_DEBHA;  Q54N80, FKBP3_DICDI;
DR   Q00688, FKBP3_HUMAN;  Q6CWE8, FKBP3_KLULA;  Q62446, FKBP3_MOUSE;
DR   O46638, FKBP3_RABIT;  P59724, FKBP3_VICFA;  Q6C4C9, FKBP3_YARLI;
DR   P38911, FKBP3_YEAST;  Q9SCY3, FKBP4_ARATH;  Q4WMV5, FKBP4_ASPFU;
DR   Q2UN37, FKBP4_ASPOR;  Q9TRY0, FKBP4_BOVIN;  Q6FK71, FKBP4_CANGA;
DR   P0CP99, FKBP4_CRYNB;  P0CP98, FKBP4_CRYNJ;  Q54NB6, FKBP4_DICDI;
DR   P0C1B0, FKBP4_EMENI;  Q4INZ9, FKBP4_GIBZE;  Q02790, FKBP4_HUMAN;
DR   P30416, FKBP4_MOUSE;  Q7SCN0, FKBP4_NEUCR;  P27124, FKBP4_RABIT;
DR   Q9QVC8, FKBP4_RAT  ;  P0C1J6, FKBP4_RHIOR;  O74191, FKBP4_SCHPO;
DR   Q26486, FKBP4_SPOFR;  Q4PIN7, FKBP4_USTMA;  Q06205, FKBP4_YEAST;
DR   Q9XT11, FKBP5_AOTNA;  Q9LDY5, FKBP5_ARATH;  Q95L05, FKBP5_CHLAE;
DR   Q54G21, FKBP5_DICDI;  Q13451, FKBP5_HUMAN;  Q64378, FKBP5_MOUSE;
DR   Q5RF88, FKBP5_PONAB;  P0C1J7, FKBP5_RHIOR;  Q9XSI2, FKBP5_SAGOE;
DR   Q9XSH5, FKBP5_SAIBB;  Q0WRJ7, FKBP6_ARATH;  A6QQ71, FKBP6_BOVIN;
DR   Q54Y27, FKBP6_DICDI;  O75344, FKBP6_HUMAN;  Q91XW8, FKBP6_MOUSE;
DR   Q9LYR5, FKBP7_ARATH;  Q9Y680, FKBP7_HUMAN;  O54998, FKBP7_MOUSE;
DR   Q5RET2, FKBP7_PONAB;  Q14318, FKBP8_HUMAN;  O35465, FKBP8_MOUSE;
DR   Q3B7U9, FKBP8_RAT  ;  Q2KJC8, FKBP9_BOVIN;  O95302, FKBP9_HUMAN;
DR   Q9Z247, FKBP9_MOUSE;  Q66H94, FKBP9_RAT  ;  Q10175, FKBPH_SCHPO;
DR   Q754K8, FKBP_ASHGO ;  Q2U316, FKBP_ASPOR ;  P28870, FKBP_CANAL ;
DR   Q6FMA3, FKBP_CANGA ;  P42458, FKBP_CORGL ;  P0CP95, FKBP_CRYNB ;
DR   P0CP94, FKBP_CRYNJ ;  O94746, FKBP_CRYNV ;  Q6BX45, FKBP_DEBHA ;
DR   Q4HZB8, FKBP_GIBZE ;  Q6CX30, FKBP_KLULA ;  O52980, FKBP_METTL ;
DR   P56989, FKBP_NEIMA ;  P0A0W2, FKBP_NEIMB ;  P0A0W3, FKBP_NEIMC ;
DR   O42993, FKBP_SCHPO ;  P28725, FKBP_STRAQ ;  Q6CF41, FKBP_YARLI ;
DR   P20081, FKBP_YEAST ;  P0AEM2, FKBX_ECO57 ;  P0AEM1, FKBX_ECOL6 ;
DR   P0AEM0, FKBX_ECOLI ;  P21863, FKBX_PSEFL ;  P0AEM3, FKBX_SHIFL ;
DR   P44760, FKBY_HAEIN ;  P30417, FKBZ_PSEAE ;  Q9PJK1, MIP_CHLMU  ;
DR   Q9Z7P3, MIP_CHLPN  ;  P26623, MIP_CHLTR  ;  P51752, MIP_COXBU  ;
DR   P53605, MIP_LEGLO  ;  P31106, MIP_LEGMI  ;  A5IGB8, MIP_LEGPC  ;
DR   Q5ZXE0, MIP_LEGPH  ;  Q70YI1, MIP_LEGPN  ;  Q09734, MIP_TRYCR  ;
DR   Q9Y536, PAL4A_HUMAN;  A2BFH1, PAL4G_HUMAN;  Q7DMA9, PAS1_ARATH ;
DR   Q9SL42, PIN1_ARATH ;  Q5BIN5, PIN1_BOVIN ;  Q9LEK8, PIN1_DIGLA ;
DR   Q13526, PIN1_HUMAN ;  Q4R383, PIN1_MACFA ;  Q94G00, PIN1_MALDO ;
DR   Q9QUR7, PIN1_MOUSE ;  P0C1J8, PIN1_RHIOR ;  O74448, PIN1_SCHPO ;
DR   Q4WJM6, PIN4_ASPFU ;  A6QPY8, PIN4_BOVIN ;  Q503Y7, PIN4_DANRE ;
DR   Q5B5W1, PIN4_EMENI ;  Q4I665, PIN4_GIBZE ;  Q9Y237, PIN4_HUMAN ;
DR   Q9CWW6, PIN4_MOUSE ;  Q7RYY4, PIN4_NEUCR ;  B5KFL3, PIN4_TAEGU ;
DR   Q6P4K8, PIN4_XENTR ;  Q7WCX5, PLP1_BORBR ;  Q7W5E0, PLP1_BORPA ;
DR   P40415, PLP1_BORPE ;  Q1RI35, PLP_RICBR  ;  Q92H91, PLP_RICCN  ;
DR   Q4UKY0, PLP_RICFE  ;  Q9ZCX6, PLP_RICPR  ;  Q68WG0, PLP_RICTY  ;
DR   Q2YPY5, PPI1_BRUA2 ;  Q57D43, PPI1_BRUAB ;  Q8YHB5, PPI1_BRUME ;
DR   Q8G0J9, PPI1_BRUSU ;  Q2FIC1, PPI1_STAA3 ;  Q2FZU9, PPI1_STAA8 ;
DR   Q2YWT2, PPI1_STAAB ;  Q5HHD1, PPI1_STAAC ;  Q99VD4, PPI1_STAAM ;
DR   Q7A6I1, PPI1_STAAN ;  Q6GID4, PPI1_STAAR ;  Q6GAX2, PPI1_STAAS ;
DR   Q7A1C0, PPI1_STAAW ;  Q5HQK8, PPI1_STAEQ ;  Q8CT84, PPI1_STAES ;
DR   Q4L4W9, PPI1_STAHJ ;  Q49W93, PPI1_STAS1 ;  P72704, PPI1_SYNY3 ;
DR   P73789, PPI2_SYNY3 ;  Q55118, PPI3_SYNY3 ;  P0C1H7, PPIA1_RHIOR;
DR   P0C1H8, PPIA2_RHIOR;  P42693, PPIA_ACIAD ;  Q6DTV9, PPIA_AOTTR ;
DR   P54985, PPIA_BLAGE ;  P62935, PPIA_BOVIN ;  P22011, PPIA_CANAL ;
DR   P62938, PPIA_CHLAE ;  P14851, PPIA_CRIGR ;  O53021, PPIA_DICD3 ;
DR   Q54SM3, PPIA_DICDI ;  P25007, PPIA_DROME ;  P14088, PPIA_ECHGR ;
DR   P0AFL5, PPIA_ECO57 ;  P0AFL4, PPIA_ECOL6 ;  P0AFL3, PPIA_ECOLI ;
DR   Q8HXS3, PPIA_FELCA ;  Q0ZQL0, PPIA_GORGO ;  Q9ZJH5, PPIA_HELPJ ;
DR   O25982, PPIA_HELPY ;  P91791, PPIA_HEMPU ;  P62937, PPIA_HUMAN ;
DR   Q0ZQK8, PPIA_HYLLA ;  Q0ZQK6, PPIA_HYLSY ;  P62940, PPIA_MACMU ;
DR   P17742, PPIA_MOUSE ;  P65763, PPIA_MYCBO ;  Q9CDE9, PPIA_MYCLE ;
DR   P65762, PPIA_MYCTU ;  P84342, PPIA_NAEFO ;  P84343, PPIA_NEOCA ;
DR   Q0ZQK7, PPIA_NOMLE ;  Q0ZQL2, PPIA_PANPA ;  Q0ZQL1, PPIA_PANTR ;
DR   P62941, PPIA_PAPAN ;  O00845, PPIA_PARPR ;  P85444, PPIA_PENGL ;
DR   P62936, PPIA_PIG   ;  Q5R8S7, PPIA_PONPY ;  Q59641, PPIA_PSEAE ;
DR   Q9TTC6, PPIA_RABIT ;  P10111, PPIA_RAT   ;  Q0ZQK3, PPIA_SAGOE ;
DR   P20753, PPIA_SALTY ;  Q26565, PPIA_SCHMA ;  Q06118, PPIA_STRAQ ;
DR   P0C1H9, PPIB1_RHIOR;  P0C1I0, PPIB2_RHIOR;  O93826, PPIB_ARTBE ;
DR   Q4WP12, PPIB_ASPFU ;  Q8X166, PPIB_ASPNG ;  Q2UGK2, PPIB_ASPOR ;
DR   P35137, PPIB_BACSU ;  P80311, PPIB_BOVIN ;  P24367, PPIB_CHICK ;
DR   P0CP79, PPIB_CRYNB ;  P0CP78, PPIB_CRYNJ ;  Q9TW32, PPIB_DICDI ;
DR   P23869, PPIB_ECOLI ;  Q5B4R3, PPIB_EMENI ;  Q4I5R9, PPIB_GIBZE ;
DR   P44499, PPIB_HAEIN ;  P23284, PPIB_HUMAN ;  P24369, PPIB_MOUSE ;
DR   P46697, PPIB_MYCLE ;  Q50639, PPIB_MYCTU ;  Q7S7Z6, PPIB_NEUCR ;
DR   Q01490, PPIB_ORPSP ;  P24368, PPIB_RAT   ;  Q27774, PPIB_SCHJA ;
DR   Q26551, PPIB_SCHMA ;  O94273, PPIB_SCHPO ;  P77949, PPIB_STRAQ ;
DR   P83221, PPIB_STRAT ;  O66105, PPIB_TREPA ;  Q6C4W6, PPIB_YARLI ;
DR   Q08E11, PPIC_BOVIN ;  P0A9L7, PPIC_ECO57 ;  P0A9L6, PPIC_ECOL6 ;
DR   P0A9L5, PPIC_ECOLI ;  P45877, PPIC_HUMAN ;  P30412, PPIC_MOUSE ;
DR   P0A266, PPIC_SALTI ;  P0A265, PPIC_SALTY ;  Q5U8Z7, PPID_AMAMU ;
DR   Q75A33, PPID_ASHGO ;  Q4WIF3, PPID_ASPFU ;  Q2U0E0, PPID_ASPOR ;
DR   P26882, PPID_BOVIN ;  P57550, PPID_BUCAI ;  Q8K987, PPID_BUCAP ;
DR   Q89A98, PPID_BUCBP ;  Q5ACI8, PPID_CANAL ;  Q6FNU6, PPID_CANGA ;
DR   P0CP81, PPID_CRYNB ;  P0CP80, PPID_CRYNJ ;  Q6BXZ7, PPID_DEBHA ;
DR   Q9UA41, PPID_DICDI ;  P0ADY2, PPID_ECOL6 ;  P0ADY1, PPID_ECOLI ;
DR   Q5B4E7, PPID_EMENI ;  Q4HXF6, PPID_GIBZE ;  Q7VKX4, PPID_HAEDU ;
DR   P44092, PPID_HAEIN ;  Q08752, PPID_HUMAN ;  Q6CL78, PPID_KLULA ;
DR   Q9CR16, PPID_MOUSE ;  Q9P3X9, PPID_NEUCR ;  Q6DGG0, PPID_RAT   ;
DR   P0C1I1, PPID_RHIOR ;  Q11004, PPID_SCHPO ;  Q4P0V4, PPID_USTMA ;
DR   Q6CBP4, PPID_YARLI ;  P53691, PPID_YEAST ;  A4FV72, PPIE_BOVIN ;
DR   Q9V3G3, PPIE_DROME ;  Q9UNP9, PPIE_HUMAN ;  Q9QZH3, PPIE_MOUSE ;
DR   Q5R723, PPIE_PONAB ;  P0C1I2, PPIE_RHIOR ;  Q26516, PPIE_SCHJA ;
DR   Q26548, PPIE_SCHMA ;  P30404, PPIF_BOVIN ;  P30405, PPIF_HUMAN ;
DR   Q99KR7, PPIF_MOUSE ;  P29117, PPIF_RAT   ;  Q13427, PPIG_HUMAN ;
DR   A2AR02, PPIG_MOUSE ;  O55035, PPIG_RAT   ;  Q4WCM6, PPIH_ASPFU ;
DR   Q2TZ33, PPIH_ASPOR ;  Q0P5D0, PPIH_BOVIN ;  P0CP83, PPIH_CRYNB ;
DR   P0CP82, PPIH_CRYNJ ;  Q5AQL0, PPIH_EMENI ;  Q4IPH4, PPIH_GIBZE ;
DR   O43447, PPIH_HUMAN ;  Q9D868, PPIH_MOUSE ;  Q7SG06, PPIH_NEUCR ;
DR   P0C1I3, PPIH_RHIOR ;  O74729, PPIH_SCHPO ;  Q4P6X6, PPIH_USTMA ;
DR   Q4WCR3, PPIL1_ASPFU;  Q8X191, PPIL1_ASPNG;  Q2U6U0, PPIL1_ASPOR;
DR   Q5E992, PPIL1_BOVIN;  P0CP85, PPIL1_CRYNB;  P0CP84, PPIL1_CRYNJ;
DR   Q5ASQ0, PPIL1_EMENI;  Q4I1Y1, PPIL1_GIBZE;  Q9Y3C6, PPIL1_HUMAN;
DR   Q9D0W5, PPIL1_MOUSE;  Q7SF72, PPIL1_NEUCR;  P0C1I4, PPIL1_RHIOR;
DR   P87051, PPIL1_SCHPO;  Q9FJX0, PPIL2_ARATH;  Q4WVU5, PPIL2_ASPFU;
DR   Q2U5W8, PPIL2_ASPOR;  P0CP91, PPIL2_CRYNB;  P0CP90, PPIL2_CRYNJ;
DR   Q5AXT6, PPIL2_EMENI;  Q4IBK5, PPIL2_GIBZE;  Q13356, PPIL2_HUMAN;
DR   Q9D787, PPIL2_MOUSE;  Q7RXA6, PPIL2_NEUCR;  P0C1J1, PPIL2_RHIOR;
DR   Q09928, PPIL2_SCHPO;  Q4P555, PPIL2_USTMA;  Q4WMB6, PPIL3_ASPFU;
DR   Q5ZLV2, PPIL3_CHICK;  P0CP87, PPIL3_CRYNB;  P0CP86, PPIL3_CRYNJ;
DR   Q54E95, PPIL3_DICDI;  Q5BAH7, PPIL3_EMENI;  Q4IPB8, PPIL3_GIBZE;
DR   Q9H2H8, PPIL3_HUMAN;  Q9D6L8, PPIL3_MOUSE;  Q6MWS8, PPIL3_NEUCR;
DR   Q812D3, PPIL3_RAT  ;  P0C1I5, PPIL3_RHIOR;  Q4PCH8, PPIL3_USTMA;
DR   Q4WAQ9, PPIL4_ASPFU;  Q2U256, PPIL4_ASPOR;  P0CP89, PPIL4_CRYNB;
DR   P0CP88, PPIL4_CRYNJ;  Q5ARI5, PPIL4_EMENI;  Q4IE79, PPIL4_GIBZE;
DR   Q8WUA2, PPIL4_HUMAN;  Q9CXG3, PPIL4_MOUSE;  Q871A4, PPIL4_NEUCR;
DR   P0C1I6, PPIL4_RHIOR;  Q9UUE4, PPIL4_SCHPO;  P0C196, PPIL4_USTMA;
DR   Q1RMP7, PPIL6_BOVIN;  Q8IXY8, PPIL6_HUMAN;  Q9D6D8, PPIL6_MOUSE;
DR   Q10724, PPIM_MAIZE ;  P29820, PPI_SYNE7  ;  Q29RZ2, PPWD1_BOVIN;
DR   Q96BP3, PPWD1_HUMAN;  Q8CEC6, PPWD1_MOUSE;  Q5NVL7, PPWD1_PONAB;
DR   Q81U45, PRSA1_BACAN;  Q81GY5, PRSA1_BACCR;  P60750, PRSA1_LACJO;
DR   Q88X05, PRSA1_LACPL;  Q92BR2, PRSA1_LISIN;  Q71ZM6, PRSA1_LISMF;
DR   Q8Y759, PRSA1_LISMO;  P60811, PRSA1_STRP1;  P0DD42, PRSA1_STRP3;
DR   Q5XBH0, PRSA1_STRP6;  Q8P0E5, PRSA1_STRP8;  P0DD43, PRSA1_STRPQ;
DR   Q81TU1, PRSA2_BACAN;  Q81GN0, PRSA2_BACCR;  P60810, PRSA2_LACJO;
DR   Q88T16, PRSA2_LACPL;  Q929F4, PRSA2_LISIN;  Q71XE6, PRSA2_LISMF;
DR   Q8Y557, PRSA2_LISMO;  P60812, PRSA2_STRP1;  P0DD44, PRSA2_STRP3;
DR   Q5X9P6, PRSA2_STRP6;  P60813, PRSA2_STRP8;  P0DD45, PRSA2_STRPQ;
DR   Q81QT1, PRSA3_BACAN;  Q81DT1, PRSA3_BACCR;  Q81CB1, PRSA4_BACCR;
DR   Q9KDN4, PRSA_BACHD ;  P24327, PRSA_BACSU ;  Q97E99, PRSA_CLOAB ;
DR   A7FPK5, PRSA_CLOB1 ;  C3KW94, PRSA_CLOB6 ;  A5I7R3, PRSA_CLOBH ;
DR   C1FNE4, PRSA_CLOBJ ;  B1IGZ5, PRSA_CLOBK ;  A7GJD2, PRSA_CLOBL ;
DR   B1KTE0, PRSA_CLOBM ;  B9DY54, PRSA_CLOK1 ;  A5N4J2, PRSA_CLOK5 ;
DR   Q0TMG9, PRSA_CLOP1 ;  Q8XHK0, PRSA_CLOPE ;  Q0SQ68, PRSA_CLOPS ;
DR   Q899I2, PRSA_CLOTE ;  Q837Y9, PRSA_ENTFA ;  B1YK87, PRSA_EXIS2 ;
DR   Q5L289, PRSA_GEOKA ;  C5D6L9, PRSA_GEOSW ;  A4IKU2, PRSA_GEOTN ;
DR   Q03QE1, PRSA_LACBA ;  Q9CEV9, PRSA_LACLA ;  P0C2B5, PRSA_LACLC ;
DR   Q02VE3, PRSA_LACLS ;  Q02473, PRSA_LACPA ;  Q1WUQ1, PRSA_LACS1 ;
DR   Q38XZ9, PRSA_LACSS ;  Q8CXK4, PRSA_OCEIH ;  Q03GD4, PRSA_PEDPA ;
DR   A7X3U8, PRSA_STAA1 ;  A6U2U4, PRSA_STAA2 ;  Q2FFQ5, PRSA_STAA3 ;
DR   Q2G2S6, PRSA_STAA8 ;  Q2YTZ6, PRSA_STAAB ;  Q5HET4, PRSA_STAAC ;
DR   A6QI23, PRSA_STAAE ;  P60747, PRSA_STAAM ;  P60748, PRSA_STAAN ;
DR   Q6GFL5, PRSA_STAAR ;  Q6G894, PRSA_STAAS ;  A8YY10, PRSA_STAAT ;
DR   P60749, PRSA_STAAW ;  Q5HN96, PRSA_STAEQ ;  Q8CNR4, PRSA_STAES ;
DR   Q3K1P9, PRSA_STRA1 ;  Q8E602, PRSA_STRA3 ;  Q8E0C6, PRSA_STRA5 ;
DR   C0M9L5, PRSA_STRE4 ;  B4U214, PRSA_STREM ;  A8AYJ0, PRSA_STRGC ;
DR   Q8CVC6, PRSA_STRMU ;  Q04KU8, PRSA_STRP2 ;  C1C6V8, PRSA_STRP7 ;
DR   B1IBE1, PRSA_STRPI ;  B8ZPD9, PRSA_STRPJ ;  Q97R51, PRSA_STRPN ;
DR   B2IPD4, PRSA_STRPS ;  Q8DQ24, PRSA_STRR6 ;  C0MCT3, PRSA_STRS7 ;
DR   A3CLY1, PRSA_STRSV ;  C1CDX6, PRSA_STRZJ ;  C1CK62, PRSA_STRZP ;
DR   C1CRR9, PRSA_STRZT ;  Q8R760, PRSA_THETN ;  Q753L9, PTPA1_ASHGO;
DR   Q4WMU5, PTPA1_ASPFU;  Q2UN27, PTPA1_ASPOR;  Q5ADP9, PTPA1_CANAL;
DR   Q6FRQ9, PTPA1_CANGA;  P0CQ01, PTPA1_CRYNB;  P0CQ00, PTPA1_CRYNJ;
DR   Q6BNW4, PTPA1_DEBHA;  Q55CJ3, PTPA1_DICDI;  Q5B6C5, PTPA1_EMENI;
DR   Q4I0M9, PTPA1_GIBZE;  Q6CYH1, PTPA1_KLULA;  Q7S6M5, PTPA1_NEUCR;
DR   O36016, PTPA1_SCHPO;  Q4P4W3, PTPA1_USTMA;  Q6CFX5, PTPA1_YARLI;
DR   P40454, PTPA1_YEAST;  Q75BY1, PTPA2_ASHGO;  Q4WSA8, PTPA2_ASPFU;
DR   Q2UCL6, PTPA2_ASPOR;  Q59ST6, PTPA2_CANAL;  Q6FK00, PTPA2_CANGA;
DR   P0CQ03, PTPA2_CRYNB;  P0CQ02, PTPA2_CRYNJ;  Q6BU97, PTPA2_DEBHA;
DR   Q54WH6, PTPA2_DICDI;  P0C153, PTPA2_EMENI;  Q4INW6, PTPA2_GIBZE;
DR   Q6CKF0, PTPA2_KLULA;  Q7SEF9, PTPA2_NEUCR;  Q9P7H4, PTPA2_SCHPO;
DR   Q4PCR0, PTPA2_USTMA;  Q6C712, PTPA2_YARLI;  Q12461, PTPA2_YEAST;
DR   Q2KJ44, PTPA_BOVIN ;  Q8SVB5, PTPA_ENCCU ;  Q15257, PTPA_HUMAN ;
DR   P58389, PTPA_MOUSE ;  Q28717, PTPA_RABIT ;  O07046, SLYD_AERHY ;
DR   P0A9L1, SLYD_ECO57 ;  P0A9L0, SLYD_ECOL6 ;  P0A9K9, SLYD_ECOLI ;
DR   P44830, SLYD_HAEIN ;  Q9ZK89, SLYD_HELPJ ;  O25748, SLYD_HELPY ;
DR   Q9CKP2, SLYD_PASMU ;  P0A9L2, SLYD_SHIFL ;  O83369, SLYD_TREPA ;
DR   Q9KNX6, SLYD_VIBCH ;  Q7CFU4, SLYD_YERPE ;  O60045, SSP1_NEUCR ;
DR   Q0VMV4, SURA_ALCBS ;  Q0AC82, SURA_ALHEH ;  Q5P7I9, SURA_AROAE ;
DR   Q1LSS0, SURA_BAUCH ;  Q493R5, SURA_BLOPB ;  Q2KXA6, SURA_BORA1 ;
DR   Q7WG19, SURA_BORBR ;  Q7W4J5, SURA_BORPA ;  Q7VU12, SURA_BORPE ;
DR   Q1BTQ6, SURA_BURCA ;  Q62MM4, SURA_BURMA ;  Q3JVW8, SURA_BURP1 ;
DR   Q63X78, SURA_BURPS ;  Q39D35, SURA_BURS3 ;  Q2T116, SURA_BURTA ;
DR   Q145L3, SURA_BURXL ;  Q1QZ33, SURA_CHRSD ;  Q7NQB0, SURA_CHRVO ;
DR   Q47VK0, SURA_COLP3 ;  Q475Q3, SURA_CUPPJ ;  Q479U4, SURA_DECAR ;
DR   P0ABZ8, SURA_ECO57 ;  P0ABZ7, SURA_ECOL6 ;  P0ABZ6, SURA_ECOLI ;
DR   Q1RGE4, SURA_ECOUT ;  Q6D0E2, SURA_ERWCT ;  Q2S9C1, SURA_HAHCH ;
DR   Q5QVN9, SURA_IDILO ;  Q5X877, SURA_LEGPA ;  Q5ZYR3, SURA_LEGPH ;
DR   Q5WZN0, SURA_LEGPL ;  Q60B78, SURA_METCA ;  Q1GZC0, SURA_METFK ;
DR   Q82W17, SURA_NITEU ;  Q2YBP3, SURA_NITMU ;  Q3JAF1, SURA_NITOC ;
DR   Q7N8V5, SURA_PHOLL ;  Q6LV39, SURA_PHOPR ;  Q121Q4, SURA_POLSJ ;
DR   Q48NT5, SURA_PSE14 ;  Q15QB3, SURA_PSEA6 ;  Q9I5U3, SURA_PSEAE ;
DR   Q4K4X7, SURA_PSEF5 ;  Q3IFD3, SURA_PSEHT ;  Q3K5T4, SURA_PSEPF ;
DR   Q88QT4, SURA_PSEPK ;  Q88A44, SURA_PSESM ;  Q4ZMG7, SURA_PSEU2 ;
DR   Q1LRA3, SURA_RALME ;  Q8Y220, SURA_RALSO ;  Q223E5, SURA_RHOFD ;
DR   Q21MS8, SURA_SACD2 ;  Q57TG8, SURA_SALCH ;  Q5PDE6, SURA_SALPA ;
DR   Q8XEV3, SURA_SALTI ;  Q7CR87, SURA_SALTY ;  Q12K61, SURA_SHEDO ;
DR   Q07YK0, SURA_SHEFN ;  Q8EB95, SURA_SHEON ;  Q0HLT0, SURA_SHESM ;
DR   Q0HS08, SURA_SHESR ;  Q326I0, SURA_SHIBS ;  Q32K41, SURA_SHIDS ;
DR   P0ABZ9, SURA_SHIFL ;  Q3Z5V6, SURA_SHISS ;  Q2NVX4, SURA_SODGM ;
DR   Q31F26, SURA_THICR ;  Q3SGF9, SURA_THIDA ;  Q9KUS0, SURA_VIBCH ;
DR   Q5E863, SURA_VIBF1 ;  Q87ST4, SURA_VIBPA ;  Q8DED4, SURA_VIBVU ;
DR   Q7MP84, SURA_VIBVY ;  Q8PP23, SURA_XANAC ;  Q3BX80, SURA_XANC5 ;
DR   Q4UR41, SURA_XANC8 ;  Q8PCE1, SURA_XANCP ;  Q2NZI6, SURA_XANOM ;
DR   Q5GWC1, SURA_XANOR ;  Q9PF40, SURA_XYLFA ;  Q87AJ0, SURA_XYLFT ;
DR   Q1C0H3, SURA_YERPA ;  Q7CG87, SURA_YERPE ;  Q1CMT0, SURA_YERPN ;
DR   Q66EQ7, SURA_YERPS ;  P82536, TLP20_SPIOL;  O49939, TLP40_SPIOL;
//
ID   5.2.1.9
DE   Farnesol 2-isomerase.
CA   2-trans,6-trans-farnesol = 2-cis,6-trans-farnesol.
//
ID   5.2.1.10
DE   2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase.
AN   2-chlorocarboxymethylenebutenolide isomerase.
AN   Chlorodienelactone isomerase.
CA   Cis-2-chloro-4-carboxymethylenebut-2-en-1,4-olide = trans-2-chloro-4-
CA   carboxymethylenebut-2-en-1,4-olide.
//
ID   5.2.1.11
DE   Deleted entry.
//
ID   5.3.1.1
DE   Triose-phosphate isomerase.
AN   Phosphotriose isomerase.
AN   Triose phosphoisomerase.
AN   Triosephosphate isomerase.
AN   Triosephosphate mutase.
CA   D-glyceraldehyde 3-phosphate = glycerone phosphate.
PR   PROSITE; PDOC00155;
DR   P36204, PGKT_THEMA ;  P36186, TPI1_GIAIN ;  P36187, TPI2_GIAIN ;
DR   Q9SKP6, TPIC_ARATH ;  Q9M4S8, TPIC_FRAAN ;  P46225, TPIC_SECCE ;
DR   P48496, TPIC_SPIOL ;  Q57D01, TPIS1_BRUAB;  Q8YHF5, TPIS1_BRUME;
DR   Q8G0F7, TPIS1_BRUSU;  Q928I1, TPIS1_LISIN;  Q71WW9, TPIS1_LISMF;
DR   Q8Y4I3, TPIS1_LISMO;  Q2K869, TPIS1_RHIEC;  Q98ME7, TPIS1_RHILO;
DR   Q92QA1, TPIS1_RHIME;  Q2YIQ6, TPIS2_BRUA2;  P0C119, TPIS2_BRUAB;
DR   Q8YCV3, TPIS2_BRUME;  Q8FVH2, TPIS2_BRUSU;  Q92EU4, TPIS2_LISIN;
DR   Q723V9, TPIS2_LISMF;  Q8YA20, TPIS2_LISMO;  Q2JZQ2, TPIS2_RHIEC;
DR   Q986N6, TPIS2_RHILO;  Q92NH8, TPIS2_RHIME;  P96985, TPIS3_RHIEC;
DR   Q1MTI4, TPISA_DANRE;  Q90XG0, TPISB_DANRE;  B0CEX1, TPIS_ACAM1 ;
DR   A1TLL4, TPIS_ACIAC ;  Q6FF44, TPIS_ACIAD ;  B7H1F6, TPIS_ACIB3 ;
DR   B7I3R5, TPIS_ACIB5 ;  B2I2M3, TPIS_ACIBC ;  B0VLU6, TPIS_ACIBS ;
DR   A3M1K0, TPIS_ACIBT ;  B0VE65, TPIS_ACIBY ;  A5FXW5, TPIS_ACICJ ;
DR   B7J7U7, TPIS_ACIF2 ;  A3N3L9, TPIS_ACTP2 ;  B3H2Z6, TPIS_ACTP7 ;
DR   B0BTK6, TPIS_ACTPJ ;  P92119, TPIS_AEDTO ;  Q9YBR1, TPIS_AERPE ;
DR   Q8UEY3, TPIS_AGRT5 ;  Q0VSS5, TPIS_ALCBS ;  Q0A773, TPIS_ALHEH ;
DR   B6EPI8, TPIS_ALISL ;  A6TU32, TPIS_ALKMQ ;  A8MFY0, TPIS_ALKOO ;
DR   B3ER35, TPIS_AMOA5 ;  Q3M7Y8, TPIS_ANAVT ;  B7GL26, TPIS_ANOFW ;
DR   P91895, TPIS_ANOME ;  O66686, TPIS_AQUAE ;  P48491, TPIS_ARATH ;
DR   O28965, TPIS_ARCFU ;  Q750Y8, TPIS_ASHGO ;  Q9HGY8, TPIS_ASPOR ;
DR   Q2NIS7, TPIS_AYWBP ;  B6YRU5, TPIS_AZOPC ;  A1K5A6, TPIS_AZOSB ;
DR   A7Z8Y3, TPIS_BACA2 ;  Q81X76, TPIS_BACAN ;  B7JFG5, TPIS_BACC0 ;
DR   Q72XY3, TPIS_BACC1 ;  B7IP22, TPIS_BACC2 ;  B7HED4, TPIS_BACC4 ;
DR   B7HW54, TPIS_BACC7 ;  Q4MQ55, TPIS_BACCE ;  A7GUR9, TPIS_BACCN ;
DR   P60180, TPIS_BACCR ;  Q631M0, TPIS_BACCZ ;  Q5L923, TPIS_BACFN ;
DR   Q64P83, TPIS_BACFR ;  Q9K715, TPIS_BACHD ;  Q6HBF1, TPIS_BACHK ;
DR   Q65EN0, TPIS_BACLD ;  P35144, TPIS_BACMD ;  A8FHJ2, TPIS_BACP2 ;
DR   Q5WDK7, TPIS_BACSK ;  P27876, TPIS_BACSU ;  Q8A0U2, TPIS_BACTN ;
DR   A6KXL2, TPIS_BACV8 ;  A9VQ50, TPIS_BACWK ;  A1US90, TPIS_BARBK ;
DR   Q8L1Z5, TPIS_BARHE ;  Q6G029, TPIS_BARQU ;  A9IS38, TPIS_BART1 ;
DR   Q1LTT4, TPIS_BAUCH ;  Q6MP18, TPIS_BDEBA ;  A1A1N2, TPIS_BIFAA ;
DR   B3DRW0, TPIS_BIFLD ;  Q8G6D5, TPIS_BIFLO ;  Q7VRL0, TPIS_BLOFL ;
DR   Q491Y3, TPIS_BLOPB ;  P82204, TPIS_BOMMO ;  Q0SPB0, TPIS_BORAP ;
DR   Q7WCQ5, TPIS_BORBR ;  Q59182, TPIS_BORBU ;  B7J0Z1, TPIS_BORBZ ;
DR   B5RKV4, TPIS_BORDL ;  Q662V9, TPIS_BORGA ;  B2S1P0, TPIS_BORHD ;
DR   Q7W575, TPIS_BORPA ;  Q7VZT5, TPIS_BORPE ;  B5RQN4, TPIS_BORRA ;
DR   Q5E956, TPIS_BOVIN ;  Q89KU3, TPIS_BRAJA ;  A5EK22, TPIS_BRASB ;
DR   A4YVD3, TPIS_BRASO ;  P57393, TPIS_BUCAI ;  Q59179, TPIS_BUCAP ;
DR   P59462, TPIS_BUCBP ;  Q057N9, TPIS_BUCCC ;  Q10657, TPIS_CAEEL ;
DR   A8MCN3, TPIS_CALMQ ;  A7ZEZ4, TPIS_CAMC1 ;  A7GWT2, TPIS_CAMC5 ;
DR   A7I1G2, TPIS_CAMHC ;  A7H5C4, TPIS_CAMJD ;  Q9PMQ6, TPIS_CAMJE ;
DR   Q5HT16, TPIS_CAMJR ;  Q9P940, TPIS_CANAL ;  P54714, TPIS_CANFA ;
DR   Q6FRI3, TPIS_CANGA ;  Q3AFD0, TPIS_CARHZ ;  Q9A733, TPIS_CAUCR ;
DR   O74067, TPIS_CENSM ;  O74044, TPIS_CENSY ;  P00940, TPIS_CHICK ;
DR   P96744, TPIS_CHLAA ;  Q5L6H0, TPIS_CHLAB ;  Q3ATA5, TPIS_CHLCH ;
DR   Q823U7, TPIS_CHLCV ;  Q253S1, TPIS_CHLFF ;  Q9PK66, TPIS_CHLMU ;
DR   B3QPT6, TPIS_CHLP8 ;  B3EPH5, TPIS_CHLPB ;  A1BHJ1, TPIS_CHLPD ;
DR   Q9Z6J6, TPIS_CHLPN ;  B0B7P5, TPIS_CHLT2 ;  B3QV54, TPIS_CHLT3 ;
DR   Q3KM32, TPIS_CHLTA ;  B0BBW0, TPIS_CHLTB ;  Q8KCH7, TPIS_CHLTE ;
DR   O84332, TPIS_CHLTR ;  Q1QSY6, TPIS_CHRSD ;  Q7NZI3, TPIS_CHRVO ;
DR   O52633, TPIS_CLOAB ;  A7FQN8, TPIS_CLOB1 ;  A6LR06, TPIS_CLOB8 ;
DR   B2UY22, TPIS_CLOBA ;  B2TPX3, TPIS_CLOBB ;  B1IDB7, TPIS_CLOBK ;
DR   A7G9Y1, TPIS_CLOBL ;  B1KTJ6, TPIS_CLOBM ;  A5N2N7, TPIS_CLOK5 ;
DR   A0PYP2, TPIS_CLONN ;  Q0TQY8, TPIS_CLOP1 ;  P81348, TPIS_CLOPA ;
DR   Q8XKU1, TPIS_CLOPE ;  A9KPF8, TPIS_CLOPH ;  Q0STD6, TPIS_CLOPS ;
DR   Q898R2, TPIS_CLOTE ;  A3DBQ1, TPIS_CLOTH ;  P0CL22, TPIS_COCIM ;
DR   Q47YJ8, TPIS_COLP3 ;  Q12574, TPIS_COPC7 ;  P21820, TPIS_COPJA ;
DR   Q6NH37, TPIS_CORDI ;  Q8FT67, TPIS_COREF ;  A4QEG0, TPIS_CORGB ;
DR   P19583, TPIS_CORGL ;  A9KBK2, TPIS_COXBN ;  A9N8X5, TPIS_COXBR ;
DR   Q83BQ3, TPIS_COXBU ;  P91919, TPIS_CULPI ;  P30741, TPIS_CULTA ;
DR   Q0KCT2, TPIS_CUPNH ;  Q473U5, TPIS_CUPPJ ;  B3R3W5, TPIS_CUPTR ;
DR   B7KL10, TPIS_CYAP7 ;  Q11PZ7, TPIS_CYTH3 ;  Q6BMB8, TPIS_DEBHA ;
DR   Q47HH8, TPIS_DECAR ;  Q3Z8H2, TPIS_DEHE1 ;  A5FRB6, TPIS_DEHSB ;
DR   Q3ZXC5, TPIS_DEHSC ;  Q1IZA2, TPIS_DEIGD ;  Q9RUP5, TPIS_DEIRA ;
DR   A9BNB6, TPIS_DELAS ;  Q30ZW0, TPIS_DESDG ;  Q72BF9, TPIS_DESVH ;
DR   B8DJI3, TPIS_DESVM ;  A1VDB2, TPIS_DESVV ;  Q869R8, TPIS_DICDI ;
DR   A5EUT5, TPIS_DICNV ;  B5YE97, TPIS_DICT6 ;  B8E2R2, TPIS_DICTD ;
DR   A8LPW1, TPIS_DINSH ;  P29613, TPIS_DROME ;  Q7JNS1, TPIS_DROSI ;
DR   O77458, TPIS_DROYA ;  A7ZUD3, TPIS_ECO24 ;  B7MI51, TPIS_ECO45 ;
DR   P0A860, TPIS_ECO57 ;  B5YZ57, TPIS_ECO5E ;  B7NU88, TPIS_ECO7I ;
DR   B7M6X0, TPIS_ECO8A ;  B1XB85, TPIS_ECODH ;  A8A724, TPIS_ECOHS ;
DR   A1AI95, TPIS_ECOK1 ;  Q0TAE5, TPIS_ECOL5 ;  P0A859, TPIS_ECOL6 ;
DR   B1IVG0, TPIS_ECOLC ;  P0A858, TPIS_ECOLI ;  B7NFL6, TPIS_ECOLU ;
DR   B6I4R2, TPIS_ECOSE ;  B1LNM2, TPIS_ECOSM ;  Q1R3Z9, TPIS_ECOUT ;
DR   Q2GGH7, TPIS_EHRCR ;  P04828, TPIS_EMENI ;  A4WG77, TPIS_ENT38 ;
DR   Q9Z6B9, TPIS_ENTCL ;  Q833J0, TPIS_ENTFA ;  O02611, TPIS_ENTHI ;
DR   Q6CZ81, TPIS_ERWCT ;  B2VF53, TPIS_ERWT9 ;  B7LVC6, TPIS_ESCF3 ;
DR   B1YLE0, TPIS_EXIS2 ;  B0S1G9, TPIS_FINM2 ;  A5FE44, TPIS_FLAJ1 ;
DR   A6GZI2, TPIS_FLAPJ ;  B0TWU2, TPIS_FRAP2 ;  Q14JZ0, TPIS_FRAT1 ;
DR   A7NEF8, TPIS_FRATF ;  P96763, TPIS_FRATH ;  B2SEZ7, TPIS_FRATM ;
DR   A0Q8C4, TPIS_FRATN ;  Q0BKA0, TPIS_FRATO ;  Q5NII7, TPIS_FRATT ;
DR   Q8RDX7, TPIS_FUSNN ;  B5EF41, TPIS_GEOBB ;  Q5KVE5, TPIS_GEOKA ;
DR   B3E9Q8, TPIS_GEOLS ;  Q39U97, TPIS_GEOMG ;  P00943, TPIS_GEOSE ;
DR   A4ISP6, TPIS_GEOTN ;  A5G381, TPIS_GEOUR ;  Q7NLT1, TPIS_GLOVI ;
DR   A9HJ86, TPIS_GLUDA ;  Q2QD07, TPIS_GORGO ;  Q0BTX8, TPIS_GRABC ;
DR   P48492, TPIS_GRAVE ;  Q7VN27, TPIS_HAEDU ;  Q4QMN8, TPIS_HAEI8 ;
DR   A5UE39, TPIS_HAEIE ;  A5UHG7, TPIS_HAEIG ;  P43727, TPIS_HAEIN ;
DR   Q0I591, TPIS_HAES1 ;  B0URI5, TPIS_HAES2 ;  Q2SML7, TPIS_HAHCH ;
DR   A1WXW9, TPIS_HALHL ;  Q5V4J7, TPIS_HALMA ;  Q9HQS4, TPIS_HALSA ;
DR   Q17YR0, TPIS_HELAH ;  Q7VGK6, TPIS_HELHP ;  B6JPU4, TPIS_HELP2 ;
DR   B5Z9W5, TPIS_HELPG ;  Q1CUW7, TPIS_HELPH ;  Q9ZMN8, TPIS_HELPJ ;
DR   B2US24, TPIS_HELPS ;  P56076, TPIS_HELPY ;  P55275, TPIS_HELVI ;
DR   A9AUN9, TPIS_HERA2 ;  A4G646, TPIS_HERAR ;  P34937, TPIS_HORVU ;
DR   P60174, TPIS_HUMAN ;  Q0C197, TPIS_HYPNA ;  Q5R0R3, TPIS_IDILO ;
DR   A6SY03, TPIS_JANMA ;  Q28RL2, TPIS_JANSC ;  A6WC54, TPIS_KINRD ;
DR   Q7X222, TPIS_KLEPN ;  Q6CJG5, TPIS_KLULA ;  Q70JN8, TPIS_KLUMA ;
DR   Q5FL49, TPIS_LACAC ;  Q03SL6, TPIS_LACBA ;  Q03AK5, TPIS_LACC3 ;
DR   B3WCW6, TPIS_LACCB ;  Q1GB25, TPIS_LACDA ;  Q04BH0, TPIS_LACDB ;
DR   O32757, TPIS_LACDE ;  Q93GB7, TPIS_LACDL ;  Q042F3, TPIS_LACGA ;
DR   A8YUE4, TPIS_LACH4 ;  Q74K79, TPIS_LACJO ;  P50918, TPIS_LACLA ;
DR   A2RL40, TPIS_LACLM ;  Q02Z48, TPIS_LACLS ;  Q88YH4, TPIS_LACPL ;
DR   Q1WSX9, TPIS_LACS1 ;  P48493, TPIS_LACSA ;  Q38Y19, TPIS_LACSS ;
DR   P00941, TPIS_LATCH ;  Q1MP91, TPIS_LAWIP ;  Q5X1A5, TPIS_LEGPA ;
DR   A5IHW5, TPIS_LEGPC ;  Q5ZRT6, TPIS_LEGPH ;  Q5WT18, TPIS_LEGPL ;
DR   P48499, TPIS_LEIME ;  Q6AF43, TPIS_LEIXX ;  B0SB22, TPIS_LEPBA ;
DR   Q04TF0, TPIS_LEPBJ ;  Q052H8, TPIS_LEPBL ;  B0SSU4, TPIS_LEPBP ;
DR   Q72QL9, TPIS_LEPIC ;  Q8F5I5, TPIS_LEPIN ;  B1HVS2, TPIS_LYSSC ;
DR   Q60HC9, TPIS_MACFA ;  P15426, TPIS_MACMU ;  A0L8V0, TPIS_MAGSM ;
DR   P12863, TPIS_MAIZE ;  A1U604, TPIS_MARAV ;  P86216, TPIS_MESAU ;
DR   Q11HU4, TPIS_MESSB ;  Q8THB0, TPIS_METAC ;  Q46DY6, TPIS_METBF ;
DR   O74025, TPIS_METBR ;  Q12UK2, TPIS_METBU ;  Q60B10, TPIS_METCA ;
DR   Q1GZK6, TPIS_METFK ;  Q9UWN5, TPIS_METFV ;  Q58923, TPIS_METJA ;
DR   Q8TUT9, TPIS_METKA ;  A2SSN5, TPIS_METLZ ;  Q8PXE2, TPIS_METMA ;
DR   A3CV22, TPIS_METMJ ;  A5ULP6, TPIS_METS3 ;  A4YGQ6, TPIS_METS5 ;
DR   O27120, TPIS_METTH ;  Q2RLU0, TPIS_MOOTA ;  Q01893, TPIS_MORSP ;
DR   P17751, TPIS_MOUSE ;  A0QHY3, TPIS_MYCA1 ;  B1MC85, TPIS_MYCA9 ;
DR   A5IYV3, TPIS_MYCAP ;  P66941, TPIS_MYCBO ;  A1KIM7, TPIS_MYCBP ;
DR   Q2SRB2, TPIS_MYCCT ;  P48779, TPIS_MYCFL ;  Q7NAQ4, TPIS_MYCGA ;
DR   P47670, TPIS_MYCGE ;  A4TC25, TPIS_MYCGI ;  P0C0J6, TPIS_MYCH2 ;
DR   Q4A8R0, TPIS_MYCH7 ;  Q4AAM8, TPIS_MYCHJ ;  P50919, TPIS_MYCHR ;
DR   P0C0J5, TPIS_MYCHY ;  P46711, TPIS_MYCLE ;  B2HP86, TPIS_MYCMM ;
DR   Q6KHM5, TPIS_MYCMO ;  Q6MSF2, TPIS_MYCMS ;  Q741C5, TPIS_MYCPA ;
DR   Q8EW34, TPIS_MYCPE ;  P47721, TPIS_MYCPI ;  P78010, TPIS_MYCPN ;
DR   Q98QA8, TPIS_MYCPU ;  Q4A5S6, TPIS_MYCS5 ;  A3PZA3, TPIS_MYCSJ ;
DR   A1UFP1, TPIS_MYCSK ;  Q1B9C0, TPIS_MYCSS ;  A5U2E0, TPIS_MYCTA ;
DR   P66940, TPIS_MYCTU ;  A0PPN4, TPIS_MYCUA ;  A1T8L2, TPIS_MYCVP ;
DR   Q1D8I9, TPIS_MYXXD ;  B2A6Z3, TPIS_NATTJ ;  Q9JW31, TPIS_NEIMA ;
DR   Q9JXT8, TPIS_NEIMB ;  Q7S2Z9, TPIS_NEUCR ;  P19118, TPIS_NICPL ;
DR   Q0AHK2, TPIS_NITEC ;  Q82TU1, TPIS_NITEU ;  Q3J827, TPIS_NITOC ;
DR   A6Q538, TPIS_NITSB ;  Q5YTQ6, TPIS_NOCFA ;  B2JA20, TPIS_NOSP7 ;
DR   Q8YP17, TPIS_NOSS1 ;  Q8ENP4, TPIS_OCEIH ;  B6JFZ2, TPIS_OLICO ;
DR   Q6YR48, TPIS_ONYPE ;  A5CC41, TPIS_ORITB ;  B3CTU9, TPIS_ORITI ;
DR   Q589R5, TPIS_ORYLA ;  P48494, TPIS_ORYSJ ;  P60175, TPIS_PANTR ;
DR   Q96VN5, TPIS_PARBA ;  A6LFF0, TPIS_PARD8 ;  Q6MD24, TPIS_PARUW ;
DR   P57936, TPIS_PASMU ;  Q03GW6, TPIS_PEDPA ;  Q3A4X5, TPIS_PELCD ;
DR   Q3B2V8, TPIS_PELLD ;  B4SBF7, TPIS_PELPB ;  A1APN8, TPIS_PELPD ;
DR   P48495, TPIS_PETHY ;  Q7MYB3, TPIS_PHOLL ;  B1VA75, TPIS_PHYAS ;
DR   Q29371, TPIS_PIG   ;  P81666, TPIS_PINPS ;  Q7KQM0, TPIS_PLAF7 ;
DR   Q07412, TPIS_PLAFA ;  P85814, TPIS_PLAOI ;  B1XUJ6, TPIS_POLNS ;
DR   A4SXQ5, TPIS_POLSQ ;  Q5R928, TPIS_PONAB ;  B2RII9, TPIS_PORG3 ;
DR   Q7MWI7, TPIS_PORGI ;  B4S9B0, TPIS_PROA2 ;  Q6A9J2, TPIS_PROAC ;
DR   A3PD39, TPIS_PROM0 ;  A2C2B2, TPIS_PROM1 ;  A8G507, TPIS_PROM2 ;
DR   A2C9H8, TPIS_PROM3 ;  A9BAK7, TPIS_PROM4 ;  A2BWF0, TPIS_PROM5 ;
DR   Q31AR4, TPIS_PROM9 ;  Q7VC41, TPIS_PROMA ;  B4F161, TPIS_PROMH ;
DR   Q7V7D2, TPIS_PROMM ;  Q7V1N4, TPIS_PROMP ;  A2BRB4, TPIS_PROMS ;
DR   Q46KV4, TPIS_PROMT ;  A4SFM8, TPIS_PROVI ;  Q48E73, TPIS_PSE14 ;
DR   A6VCK5, TPIS_PSEA7 ;  B7V1G0, TPIS_PSEA8 ;  Q02FS4, TPIS_PSEAB ;
DR   Q9HV51, TPIS_PSEAE ;  Q1IF47, TPIS_PSEE4 ;  Q4KIF9, TPIS_PSEF5 ;
DR   Q3IE60, TPIS_PSEHT ;  A4XYE4, TPIS_PSEMY ;  A5W991, TPIS_PSEP1 ;
DR   Q3KI88, TPIS_PSEPF ;  B0KHY2, TPIS_PSEPG ;  Q88DV4, TPIS_PSEPK ;
DR   B1J266, TPIS_PSEPW ;  Q87WQ1, TPIS_PSESM ;  P95576, TPIS_PSEU2 ;
DR   A4VPP4, TPIS_PSEU5 ;  Q4FVL9, TPIS_PSYA2 ;  Q1QEP9, TPIS_PSYCK ;
DR   A1SWS5, TPIS_PSYIN ;  A5WBS1, TPIS_PSYWF ;  Q9UXX2, TPIS_PYRAB ;
DR   Q8ZX28, TPIS_PYRAE ;  A4WIJ6, TPIS_PYRAR ;  A3MUC6, TPIS_PYRCJ ;
DR   P62002, TPIS_PYRFU ;  O59536, TPIS_PYRHO ;  A1RUV7, TPIS_PYRIL ;
DR   Q5JHG3, TPIS_PYRKO ;  P62003, TPIS_PYRWO ;  P00939, TPIS_RABIT ;
DR   Q8XXP9, TPIS_RALSO ;  P48500, TPIS_RAT   ;  Q7UP89, TPIS_RHOBA ;
DR   Q21YC9, TPIS_RHOFD ;  Q07NF3, TPIS_RHOP5 ;  Q215B4, TPIS_RHOPB ;
DR   Q0S0J3, TPIS_RHOSR ;  A7NI03, TPIS_ROSCS ;  A5UZW4, TPIS_ROSS1 ;
DR   Q1AUH8, TPIS_RUBXD ;  A1AXX3, TPIS_RUTMC ;  A4FBM6, TPIS_SACEN ;
DR   B5F0R2, TPIS_SALA4 ;  Q57HD6, TPIS_SALCH ;  B5FPS9, TPIS_SALDC ;
DR   B5QX14, TPIS_SALEP ;  B5RF90, TPIS_SALG2 ;  B4TCL7, TPIS_SALHS ;
DR   B4T0S7, TPIS_SALNS ;  Q5PJE0, TPIS_SALPA ;  A9MZG8, TPIS_SALPB ;
DR   B5BJJ8, TPIS_SALPK ;  B4TPU2, TPIS_SALSV ;  Q8Z2Y2, TPIS_SALTI ;
DR   Q8ZKP7, TPIS_SALTY ;  Q27775, TPIS_SCHJA ;  P48501, TPIS_SCHMA ;
DR   P07669, TPIS_SCHPO ;  P46226, TPIS_SECCE ;  A8GLA8, TPIS_SERP5 ;
DR   A1S458, TPIS_SHEAM ;  A3D7L0, TPIS_SHEB5 ;  A6WRH2, TPIS_SHEB8 ;
DR   A9KZX5, TPIS_SHEB9 ;  Q12QI5, TPIS_SHEDO ;  Q086H6, TPIS_SHEFN ;
DR   B0TQA6, TPIS_SHEHH ;  A3QGU9, TPIS_SHELP ;  Q8EHL9, TPIS_SHEON ;
DR   A8H744, TPIS_SHEPA ;  A4Y9C4, TPIS_SHEPC ;  B8CKG9, TPIS_SHEPW ;
DR   A0KTZ2, TPIS_SHESA ;  A8FYS4, TPIS_SHESH ;  Q0HLG5, TPIS_SHESM ;
DR   Q0HXR9, TPIS_SHESR ;  A1RGX1, TPIS_SHESW ;  B1KRR4, TPIS_SHEWM ;
DR   B2TVR1, TPIS_SHIB3 ;  Q31U71, TPIS_SHIBS ;  Q32A84, TPIS_SHIDS ;
DR   Q0SZA9, TPIS_SHIF8 ;  P0A861, TPIS_SHIFL ;  Q3YV59, TPIS_SHISS ;
DR   Q5LQ75, TPIS_SILPO ;  Q1GIL9, TPIS_SILST ;  Q2NQX4, TPIS_SODGM ;
DR   Q01SE4, TPIS_SOLUE ;  A7WZS8, TPIS_STAA1 ;  A6TZQ3, TPIS_STAA2 ;
DR   Q2FIL9, TPIS_STAA3 ;  Q2G030, TPIS_STAA8 ;  A5IQX8, TPIS_STAA9 ;
DR   Q2YSF0, TPIS_STAAB ;  Q5HHP3, TPIS_STAAC ;  A6QF83, TPIS_STAAE ;
DR   P68822, TPIS_STAAM ;  P99133, TPIS_STAAN ;  Q6GIL6, TPIS_STAAR ;
DR   Q6GB56, TPIS_STAAS ;  A8Z1A2, TPIS_STAAT ;  P68823, TPIS_STAAU ;
DR   P68824, TPIS_STAAW ;  Q5HQV2, TPIS_STAEQ ;  Q8CTD5, TPIS_STAES ;
DR   Q4L4K5, TPIS_STAHJ ;  Q49W01, TPIS_STAS1 ;  P48497, TPIS_STELP ;
DR   Q3K1U3, TPIS_STRA1 ;  Q8E644, TPIS_STRA3 ;  Q8E0H0, TPIS_STRA5 ;
DR   Q829W1, TPIS_STRAW ;  Q9Z520, TPIS_STRCO ;  B4U3U0, TPIS_STREM ;
DR   A8AWA1, TPIS_STRGC ;  B4SQT8, TPIS_STRM5 ;  B2FNY1, TPIS_STRMK ;
DR   P72484, TPIS_STRMU ;  P69887, TPIS_STRP1 ;  Q04JH4, TPIS_STRP2 ;
DR   P0DG10, TPIS_STRP3 ;  B5E6L7, TPIS_STRP4 ;  Q5XD48, TPIS_STRP6 ;
DR   Q8P1W3, TPIS_STRP8 ;  Q1JCT5, TPIS_STRPB ;  Q1JMR2, TPIS_STRPC ;
DR   Q1JHV5, TPIS_STRPD ;  Q1J7N3, TPIS_STRPF ;  A2RFQ3, TPIS_STRPG ;
DR   B1ICZ4, TPIS_STRPI ;  Q48UK4, TPIS_STRPM ;  P66942, TPIS_STRPN ;
DR   P0DG11, TPIS_STRPQ ;  B5XKI2, TPIS_STRPZ ;  P66943, TPIS_STRR6 ;
DR   A4VZZ4, TPIS_STRS2 ;  A4VTQ8, TPIS_STRSY ;  Q5M100, TPIS_STRT1 ;
DR   Q8VVC1, TPIS_STRT2 ;  Q03LW9, TPIS_STRTD ;  Q4JCD8, TPIS_SULAC ;
DR   Q30PQ5, TPIS_SULDN ;  A6QCD3, TPIS_SULNB ;  Q97VM8, TPIS_SULSO ;
DR   Q96YZ9, TPIS_SULTO ;  Q67SW4, TPIS_SYMTH ;  Q2JX75, TPIS_SYNJA ;
DR   Q2JJQ9, TPIS_SYNJB ;  B1XPX4, TPIS_SYNP2 ;  A5GLP6, TPIS_SYNPW ;
DR   Q7U804, TPIS_SYNPX ;  A5GSL8, TPIS_SYNR3 ;  Q0IAV3, TPIS_SYNS3 ;
DR   Q3AYN1, TPIS_SYNS9 ;  Q59994, TPIS_SYNY3 ;  Q9GTX8, TPIS_TAESO ;
DR   Q9HLB6, TPIS_THEAC ;  Q8DKA0, TPIS_THEEB ;  B0K880, TPIS_THEP3 ;
DR   B0K6X4, TPIS_THEPX ;  Q72K37, TPIS_THET2 ;  Q5SJR1, TPIS_THET8 ;
DR   Q8NKN9, TPIS_THETE ;  Q8R966, TPIS_THETN ;  Q978V5, TPIS_THEVO ;
DR   B5YL53, TPIS_THEYD ;  Q31HG2, TPIS_THICR ;  Q3SJQ7, TPIS_THIDA ;
DR   Q73NB9, TPIS_TREDE ;  O83548, TPIS_TREPA ;  B2S3C9, TPIS_TREPS ;
DR   Q115Y7, TPIS_TRIEI ;  Q83HP9, TPIS_TROW8 ;  Q83GI1, TPIS_TROWT ;
DR   P04789, TPIS_TRYBB ;  P52270, TPIS_TRYCR ;  B1GZW3, TPIS_UNCTG ;
DR   B1AIG9, TPIS_UREP2 ;  Q9PQW2, TPIS_UREPA ;  A5CVF7, TPIS_VESOH ;
DR   Q9KNR1, TPIS_VIBCH ;  Q5E8E5, TPIS_VIBF1 ;  B5FFY1, TPIS_VIBFM ;
DR   P50921, TPIS_VIBMA ;  Q87T31, TPIS_VIBPA ;  Q56738, TPIS_VIBSA ;
DR   Q8DCQ3, TPIS_VIBVU ;  Q7MH47, TPIS_VIBVY ;  Q8D2T0, TPIS_WIGBR ;
DR   Q73IR2, TPIS_WOLPM ;  B3CPY7, TPIS_WOLPP ;  Q7MA77, TPIS_WOLSU ;
DR   Q5GSM8, TPIS_WOLTR ;  Q8PJ38, TPIS_XANAC ;  Q3BRM7, TPIS_XANC5 ;
DR   Q4UWC0, TPIS_XANC8 ;  Q8P7T0, TPIS_XANCP ;  P96190, TPIS_XANFL ;
DR   Q2P0V3, TPIS_XANOM ;  B2SVM1, TPIS_XANOP ;  A7INK7, TPIS_XANP2 ;
DR   Q7ZWN5, TPIS_XENLA ;  B0BM40, TPIS_XENTR ;  B2I782, TPIS_XYLF2 ;
DR   Q9PGJ7, TPIS_XYLFA ;  B0U1W3, TPIS_XYLFM ;  Q87EQ7, TPIS_XYLFT ;
DR   Q6C2T9, TPIS_YARLI ;  P00942, TPIS_YEAST ;  A1JHZ7, TPIS_YERE8 ;
DR   A7FCW8, TPIS_YERP3 ;  Q1C2A4, TPIS_YERPA ;  B2JZB1, TPIS_YERPB ;
DR   Q8ZJK9, TPIS_YERPE ;  A9R6B0, TPIS_YERPG ;  Q1CD40, TPIS_YERPN ;
DR   A4TSA1, TPIS_YERPP ;  Q66GA1, TPIS_YERPS ;  B1JQ90, TPIS_YERPY ;
DR   Q9C401, TPIS_ZYGBA ;
//
ID   5.3.1.2
DE   Deleted entry.
//
ID   5.3.1.3
DE   Arabinose isomerase.
AN   D-arabinose isomerase.
AN   L-fucose isomerase.
CA   D-arabinose = D-ribulose.
CC   -!- Also acts on L-fucose and, more slowly, on L-galactose and D-altrose.
//
ID   5.3.1.4
DE   L-arabinose isomerase.
CA   L-arabinose = L-ribulose.
DR   Q65GC0, ARAA1_BACLD;  Q97JE4, ARAA1_CLOAB;  Q65J10, ARAA2_BACLD;
DR   Q97JE0, ARAA2_CLOAB;  Q1IUW9, ARAA_ACIBL ;  A0LT86, ARAA_ACIC1 ;
DR   A6VLM2, ARAA_ACTSZ ;  A0KJI0, ARAA_AERHH ;  A4SNH3, ARAA_AERS4 ;
DR   B7GGW0, ARAA_ANOFW ;  A1RAY5, ARAA_ARTAT ;  A0JRF5, ARAA_ARTS2 ;
DR   Q9KBQ2, ARAA_BACHD ;  Q5WL05, ARAA_BACSK ;  P94523, ARAA_BACSU ;
DR   Q8AAW1, ARAA_BACTN ;  A6L2R5, ARAA_BACV8 ;  B8DV60, ARAA_BIFA0 ;
DR   A1A3A8, ARAA_BIFAA ;  B3DTJ5, ARAA_BIFLD ;  Q8G7J3, ARAA_BIFLO ;
DR   B3PD57, ARAA_CELJU ;  A8ALP0, ARAA_CITK8 ;  A5CPB7, ARAA_CLAM3 ;
DR   B0RIE3, ARAA_CLAMS ;  A6M1T6, ARAA_CLOB8 ;  A7ZHF3, ARAA_ECO24 ;
DR   B7UIA8, ARAA_ECO27 ;  B7MAI5, ARAA_ECO45 ;  B7L4I3, ARAA_ECO55 ;
DR   P58538, ARAA_ECO57 ;  B5YZ98, ARAA_ECO5E ;  B7NHG8, ARAA_ECO7I ;
DR   B7MNR9, ARAA_ECO81 ;  B7M0F7, ARAA_ECO8A ;  C4ZPY5, ARAA_ECOBW ;
DR   A7ZW12, ARAA_ECOHS ;  A1A7A9, ARAA_ECOK1 ;  Q0TLS8, ARAA_ECOL5 ;
DR   Q8FL89, ARAA_ECOL6 ;  B1IRB6, ARAA_ECOLC ;  P08202, ARAA_ECOLI ;
DR   B7N7T6, ARAA_ECOLU ;  B6HZ42, ARAA_ECOSE ;  B1LFZ6, ARAA_ECOSM ;
DR   Q1RGD7, ARAA_ECOUT ;  A4W6G6, ARAA_ENT38 ;  Q6D4W5, ARAA_ERWCT ;
DR   B2VER0, ARAA_ERWT9 ;  B7LVT3, ARAA_ESCF3 ;  A5FKW3, ARAA_FLAJ1 ;
DR   Q5KYP7, ARAA_GEOKA ;  Q9S467, ARAA_GEOSE ;  A4IPA1, ARAA_GEOTN ;
DR   A0LZ81, ARAA_GRAFK ;  A9B689, ARAA_HERA2 ;  B5Y1Y1, ARAA_KLEP3 ;
DR   A6T4K0, ARAA_KLEP7 ;  Q48433, ARAA_KLEPN ;  Q03PR5, ARAA_LACBA ;
DR   Q88S84, ARAA_LACPL ;  Q38UH2, ARAA_LACSS ;  B1Y1J9, ARAA_LEPCP ;
DR   Q03XW2, ARAA_LEUMM ;  Q65WJ5, ARAA_MANSM ;  A0QT53, ARAA_MYCS2 ;
DR   Q9RHG2, ARAA_MYCSM ;  A1SDP0, ARAA_NOCSJ ;  Q8EMP4, ARAA_OCEIH ;
DR   B1ZRZ1, ARAA_OPITP ;  C6DH19, ARAA_PECCP ;  Q03HQ0, ARAA_PEDPA ;
DR   Q21MP3, ARAA_SACD2 ;  B5F783, ARAA_SALA4 ;  A9MQF1, ARAA_SALAR ;
DR   Q57TF9, ARAA_SALCH ;  B5FI45, ARAA_SALDC ;  B5R1T9, ARAA_SALEP ;
DR   B5RGD3, ARAA_SALG2 ;  B4TJ59, ARAA_SALHS ;  B4SU23, ARAA_SALNS ;
DR   Q5PDF2, ARAA_SALPA ;  A9MYN8, ARAA_SALPB ;  B5BL43, ARAA_SALPK ;
DR   B4TWU8, ARAA_SALSV ;  P58539, ARAA_SALTI ;  P06189, ARAA_SALTY ;
DR   A8GE04, ARAA_SERP5 ;  B8EEN5, ARAA_SHEB2 ;  A0KWX7, ARAA_SHESA ;
DR   Q0HIR5, ARAA_SHESM ;  Q0HV71, ARAA_SHESR ;  A1RJD6, ARAA_SHESW ;
DR   B2U268, ARAA_SHIB3 ;  Q326H3, ARAA_SHIBS ;  Q32K31, ARAA_SHIDS ;
DR   Q0T8D5, ARAA_SHIF8 ;  Q7UDT4, ARAA_SHIFL ;  Q3Z5U9, ARAA_SHISS ;
DR   Q9WYB3, ARAA_THEMA ;  B9KC39, ARAA_THENN ;  A5IKE5, ARAA_THEP1 ;
DR   B1L9M7, ARAA_THESQ ;  C4L8B5, ARAA_TOLAT ;  Q87FK3, ARAA_VIBPA ;
DR   A1JMB6, ARAA_YERE8 ;  A7FHY4, ARAA_YERP3 ;  Q1C7J3, ARAA_YERPA ;
DR   B2K4K7, ARAA_YERPB ;  P58540, ARAA_YERPE ;  A9R8V1, ARAA_YERPG ;
DR   Q1CIX9, ARAA_YERPN ;  A4TJ19, ARAA_YERPP ;  Q66AF8, ARAA_YERPS ;
DR   B1JKM7, ARAA_YERPY ;
//
ID   5.3.1.5
DE   Xylose isomerase.
AN   D-xylose ketoisomerase.
CA   D-xylose = D-xylulose.
CF   Magnesium.
CC   -!- Some enzymes also convert D-glucose to D-fructose.
PR   PROSITE; PDOC00156;
DR   Q8PLL9, XYLA1_XANAC;  Q4UTU6, XYLA1_XANC8;  Q8P9T9, XYLA1_XANCP;
DR   Q5GYQ7, XYLA1_XANOR;  Q8PEW5, XYLA2_XANAC;  Q4UNZ4, XYLA2_XANC8;
DR   Q8P3H1, XYLA2_XANCP;  Q5GUF2, XYLA2_XANOR;  P12851, XYLA_ACTMI ;
DR   A3N3K2, XYLA_ACTP2 ;  B3H2X9, XYLA_ACTP7 ;  B0BTI9, XYLA_ACTPJ ;
DR   A6VLM8, XYLA_ACTSZ ;  B9JAF5, XYLA_AGRRK ;  Q8U7G6, XYLA_AGRT5 ;
DR   B9JSR6, XYLA_AGRVS ;  P10654, XYLA_AMPSP ;  B9MPG8, XYLA_ANATD ;
DR   Q9FKK7, XYLA_ARATH ;  B8HA51, XYLA_ARTCA ;  A0JXN9, XYLA_ARTS2 ;
DR   P12070, XYLA_ARTS7 ;  A7Z522, XYLA_BACA2 ;  Q739D2, XYLA_BACC1 ;
DR   Q5LCV9, XYLA_BACFN ;  Q64U20, XYLA_BACFR ;  Q9K993, XYLA_BACHD ;
DR   P77832, XYLA_BACLD ;  O08325, XYLA_BACMD ;  A8FE33, XYLA_BACP2 ;
DR   E0TVS5, XYLA_BACPZ ;  Q5WKJ3, XYLA_BACSK ;  P0CI80, XYLA_BACSU ;
DR   P54272, XYLA_BACSW ;  Q8A9M2, XYLA_BACTN ;  A6L792, XYLA_BACV8 ;
DR   A1A0H0, XYLA_BIFAA ;  B3DR33, XYLA_BIFLD ;  Q8G3Q1, XYLA_BIFLO ;
DR   Q89VC7, XYLA_BRAJA ;  B2SA37, XYLA_BRUA1 ;  Q2YMQ2, XYLA_BRUA2 ;
DR   Q57EI4, XYLA_BRUAB ;  A9M9H3, XYLA_BRUC2 ;  C0RHQ0, XYLA_BRUMB ;
DR   Q8YFX5, XYLA_BRUME ;  A5VPA1, XYLA_BRUO2 ;  B0CKM9, XYLA_BRUSI ;
DR   Q8G204, XYLA_BRUSU ;  B1Z405, XYLA_BURA4 ;  Q1BG90, XYLA_BURCA ;
DR   B1KB47, XYLA_BURCC ;  A0KE56, XYLA_BURCH ;  B4ENA5, XYLA_BURCJ ;
DR   Q0B1U7, XYLA_BURCM ;  A9ARG7, XYLA_BURM1 ;  B2JFE9, XYLA_BURP8 ;
DR   B2T929, XYLA_BURPP ;  Q2SW40, XYLA_BURTA ;  A4JSU5, XYLA_BURVG ;
DR   Q13RB8, XYLA_BURXL ;  A5CPC1, XYLA_CLAM3 ;  B0RIF1, XYLA_CLAMS ;
DR   A8LP53, XYLA_DINSH ;  A7ZTB2, XYLA_ECO24 ;  B7ULC6, XYLA_ECO27 ;
DR   B7MES1, XYLA_ECO45 ;  B7L6Y0, XYLA_ECO55 ;  Q7A9X4, XYLA_ECO57 ;
DR   B5YVL8, XYLA_ECO5E ;  B7NP65, XYLA_ECO7I ;  B7N1L9, XYLA_ECO81 ;
DR   B7M3I8, XYLA_ECO8A ;  C4ZXF6, XYLA_ECOBW ;  B1X8I1, XYLA_ECODH ;
DR   A8A623, XYLA_ECOHS ;  Q0TBN7, XYLA_ECOL5 ;  Q8FCE3, XYLA_ECOL6 ;
DR   B1IZM7, XYLA_ECOLC ;  P00944, XYLA_ECOLI ;  B7NEL7, XYLA_ECOLU ;
DR   B6I3D6, XYLA_ECOSE ;  B1LJC7, XYLA_ECOSM ;  A4W566, XYLA_ENT38 ;
DR   Q7C3R3, XYLA_ENTFA ;  A7MNI5, XYLA_ENTS8 ;  Q6DB05, XYLA_ERWCT ;
DR   B7LTH9, XYLA_ESCF3 ;  Q6T6K9, XYLA_FERGO ;  Q5KYS6, XYLA_GEOKA ;
DR   P54273, XYLA_GEOSE ;  A4IP67, XYLA_GEOTN ;  Q4QLI2, XYLA_HAEI8 ;
DR   A5UCZ3, XYLA_HAEIE ;  A5UIN7, XYLA_HAEIG ;  P44398, XYLA_HAEIN ;
DR   B0UT19, XYLA_HAES2 ;  Q40082, XYLA_HORVU ;  P29442, XYLA_KLEPN ;
DR   Q03TX3, XYLA_LACBA ;  P29443, XYLA_LACBR ;  Q9CFG7, XYLA_LACLA ;
DR   Q02Y75, XYLA_LACLS ;  P21938, XYLA_LACPE ;  A0AF79, XYLA_LISW6 ;
DR   Q65PY0, XYLA_MANSM ;  A6VWH1, XYLA_MARMS ;  Q11EH9, XYLA_MESSB ;
DR   Q2GAB9, XYLA_NOVAD ;  Q8ELU7, XYLA_OCEIH ;  A6X4G3, XYLA_OCHA4 ;
DR   C6DIH5, XYLA_PECCP ;  Q03HN1, XYLA_PEDPA ;  Q7N4P7, XYLA_PHOLL ;
DR   Q6LUY7, XYLA_PHOPR ;  Q48J73, XYLA_PSE14 ;  Q15PG0, XYLA_PSEA6 ;
DR   C3K8E3, XYLA_PSEFS ;  Q3KDW0, XYLA_PSEPF ;  Q880Z4, XYLA_PSESM ;
DR   Q4ZSF5, XYLA_PSEU2 ;  B3Q0R5, XYLA_RHIE6 ;  Q2K433, XYLA_RHIEC ;
DR   Q1MBL8, XYLA_RHIL3 ;  Q98CR8, XYLA_RHILO ;  B5ZQV6, XYLA_RHILW ;
DR   Q92LW9, XYLA_RHIME ;  C3M8Y0, XYLA_RHISN ;  Q7UVG2, XYLA_RHOBA ;
DR   A3PNM4, XYLA_RHOS1 ;  Q3IYM4, XYLA_RHOS4 ;  A4WVT8, XYLA_RHOS5 ;
DR   B9KPP8, XYLA_RHOSK ;  Q162B6, XYLA_ROSDO ;  Q9S306, XYLA_RUMFL ;
DR   B5EX72, XYLA_SALA4 ;  Q57IG0, XYLA_SALCH ;  B5FLD6, XYLA_SALDC ;
DR   B5R4P8, XYLA_SALEP ;  B5RGL6, XYLA_SALG2 ;  B4T952, XYLA_SALHS ;
DR   B4SWK9, XYLA_SALNS ;  Q5PLM6, XYLA_SALPA ;  A9MUV0, XYLA_SALPB ;
DR   C0Q1C2, XYLA_SALPC ;  B4TZ55, XYLA_SALSV ;  Q7C637, XYLA_SALTI ;
DR   Q8ZL90, XYLA_SALTY ;  A8G7W8, XYLA_SERP5 ;  B2U560, XYLA_SHIB3 ;
DR   Q31V53, XYLA_SHIBS ;  Q3YVV0, XYLA_SHISS ;  Q5LV46, XYLA_SILPO ;
DR   Q1GKQ4, XYLA_SILST ;  A6UD89, XYLA_SINMW ;  Q022S9, XYLA_SOLUE ;
DR   P27157, XYLA_STAXY ;  P24299, XYLA_STRAL ;  Q93HF3, XYLA_STRAW ;
DR   Q9S3Z4, XYLA_STRCK ;  Q9L0B8, XYLA_STRCO ;  P50910, XYLA_STRDI ;
DR   Q9RFM4, XYLA_STRLI ;  P37031, XYLA_STRMR ;  Q93RJ9, XYLA_STROI ;
DR   P15587, XYLA_STROL ;  P22857, XYLA_STRRO ;  P24300, XYLA_STRRU ;
DR   P19149, XYLA_STRS8 ;  Q9L558, XYLA_STRTM ;  P14405, XYLA_STRVN ;
DR   P09033, XYLA_STRVO ;  O82845, XYLA_TETHA ;  P56681, XYLA_THECA ;
DR   Q9X1Z5, XYLA_THEMA ;  P45687, XYLA_THENE ;  B9K7G3, XYLA_THENN ;
DR   A5ILR5, XYLA_THEP1 ;  P22842, XYLA_THEP3 ;  B0K1L3, XYLA_THEPX ;
DR   P30435, XYLA_THESA ;  B1LB08, XYLA_THESQ ;  P26997, XYLA_THET8 ;
DR   P29441, XYLA_THETC ;  P19148, XYLA_THETU ;  Q9KGU2, XYLA_THEYO ;
DR   Q3BMF2, XYLA_XANC5 ;  Q2NXR2, XYLA_XANOM ;  A1JT10, XYLA_YERE8 ;
DR   A7FP68, XYLA_YERP3 ;  Q1C0D3, XYLA_YERPA ;  B2K7D2, XYLA_YERPB ;
DR   Q8Z9Z1, XYLA_YERPE ;  A9R5Q1, XYLA_YERPG ;  Q1CDB8, XYLA_YERPN ;
DR   A4TS63, XYLA_YERPP ;  Q663Y3, XYLA_YERPS ;  B1JH40, XYLA_YERPY ;
//
ID   5.3.1.6
DE   Ribose-5-phosphate isomerase.
AN   5-phosphoribose isomerase.
AN   D-ribose-5-phosphate ketol-isomerase.
AN   Phosphopentoseisomerase.
AN   Phosphopentosisomerase.
AN   Phosphoriboisomerase.
AN   Ribose 5-phosphate epimerase.
AN   Ribose phosphate isomerase.
CA   D-ribose 5-phosphate = D-ribulose 5-phosphate.
CC   -!- Also acts on D-ribose 5-diphosphate and D-ribose 5-triphosphate.
DR   Q8EN78, RPIA1_OCEIH;  Q8ZHH8, RPIA1_YERPE;  Q666Q7, RPIA1_YERPS;
DR   Q8EMZ1, RPIA2_OCEIH;  Q8ZGJ9, RPIA2_YERPE;  Q66CS8, RPIA2_YERPS;
DR   Q6FCI6, RPIA_ACIAD ;  B7H207, RPIA_ACIB3 ;  B7I936, RPIA_ACIB5 ;
DR   B2I2V7, RPIA_ACIBC ;  B0VQK6, RPIA_ACIBS ;  A3M5Z8, RPIA_ACIBT ;
DR   B0V681, RPIA_ACIBY ;  B7J5S6, RPIA_ACIF2 ;  B5ENJ5, RPIA_ACIF5 ;
DR   A3N2A1, RPIA_ACTP2 ;  B3H285, RPIA_ACTP7 ;  B0BR42, RPIA_ACTPJ ;
DR   A6VQH4, RPIA_ACTSZ ;  A0KLT5, RPIA_AERHH ;  Q9YEA9, RPIA_AERPE ;
DR   A4SLF3, RPIA_AERS4 ;  B9JFX9, RPIA_AGRRK ;  Q8UEZ0, RPIA_AGRT5 ;
DR   B9JW57, RPIA_AGRVS ;  Q0VL94, RPIA_ALCBS ;  Q0ACJ4, RPIA_ALHEH ;
DR   B6EKP6, RPIA_ALISL ;  Q3M4J7, RPIA_ANAVT ;  Q9ZU38, RPIA_ARATH ;
DR   O29319, RPIA_ARCFU ;  Q5P7L9, RPIA_AROAE ;  Q75CJ6, RPIA_ASHGO ;
DR   A1K9D7, RPIA_AZOSB ;  Q81PL1, RPIA_BACAN ;  Q736S8, RPIA_BACC1 ;
DR   Q81CG8, RPIA_BACCR ;  Q63AF7, RPIA_BACCZ ;  Q6HHU6, RPIA_BACHK ;
DR   Q5WCM4, RPIA_BACSK ;  A9VID8, RPIA_BACWK ;  A1USF7, RPIA_BARBK ;
DR   Q6G3V6, RPIA_BARHE ;  Q6FZP1, RPIA_BARQU ;  Q1LSJ4, RPIA_BAUCH ;
DR   A1A0A9, RPIA_BIFAA ;  B3DQF7, RPIA_BIFLD ;  Q8G3X9, RPIA_BIFLO ;
DR   B7GN96, RPIA_BIFLS ;  Q7VRG1, RPIA_BLOFL ;  Q493E8, RPIA_BLOPB ;
DR   Q2KYQ1, RPIA_BORA1 ;  Q0SMJ6, RPIA_BORAP ;  Q7WH03, RPIA_BORBR ;
DR   O51601, RPIA_BORBU ;  B7J2L2, RPIA_BORBZ ;  B2S100, RPIA_BORHD ;
DR   Q7W9Q5, RPIA_BORPA ;  A9IJV4, RPIA_BORPD ;  Q7VWC1, RPIA_BORPE ;
DR   Q3T186, RPIA_BOVIN ;  Q89NS9, RPIA_BRAJA ;  Q8YH30, RPIA_BRUME ;
DR   Q8G0S7, RPIA_BRUSU ;  B8D9J2, RPIA_BUCA5 ;  P57489, RPIA_BUCAI ;
DR   Q8K9E2, RPIA_BUCAP ;  B8D7U4, RPIA_BUCAT ;  Q89AD5, RPIA_BUCBP ;
DR   B1YPI1, RPIA_BURA4 ;  Q1BWM9, RPIA_BURCA ;  B1K0R9, RPIA_BURCC ;
DR   A0K724, RPIA_BURCH ;  B4E852, RPIA_BURCJ ;  Q0BFR5, RPIA_BURCM ;
DR   A3MJY8, RPIA_BURM7 ;  A2S2I6, RPIA_BURM9 ;  Q62K38, RPIA_BURMA ;
DR   A1V4B2, RPIA_BURMS ;  A3NUR6, RPIA_BURP0 ;  Q3JST3, RPIA_BURP1 ;
DR   A3N919, RPIA_BURP6 ;  B2JKP8, RPIA_BURP8 ;  B2T3F4, RPIA_BURPP ;
DR   Q63TU6, RPIA_BURPS ;  Q39GY0, RPIA_BURS3 ;  A4JE17, RPIA_BURVG ;
DR   Q13ZQ5, RPIA_BURXL ;  P41994, RPIA_CAEEL ;  Q5AJ92, RPIA_CANAL ;
DR   Q6FLF8, RPIA_CANGA ;  B8GYT0, RPIA_CAUCN ;  Q9A5Z4, RPIA_CAUCR ;
DR   B0T734, RPIA_CAUSK ;  A9WIA0, RPIA_CHLAA ;  Q5L5N7, RPIA_CHLAB ;
DR   B8G2V0, RPIA_CHLAD ;  Q822P7, RPIA_CHLCV ;  Q254Z5, RPIA_CHLFF ;
DR   Q9PKI0, RPIA_CHLMU ;  Q9Z942, RPIA_CHLPN ;  B9LCG3, RPIA_CHLSY ;
DR   B0B9W3, RPIA_CHLT2 ;  Q3KME9, RPIA_CHLTA ;  B0BBJ3, RPIA_CHLTB ;
DR   O84215, RPIA_CHLTR ;  Q7NYL4, RPIA_CHRVO ;  Q485H8, RPIA_COLP3 ;
DR   B6J4C4, RPIA_COXB1 ;  B6J3K5, RPIA_COXB2 ;  A9KBD3, RPIA_COXBN ;
DR   A9NBF7, RPIA_COXBR ;  Q83FB4, RPIA_COXBU ;  P0CR19, RPIA_CRYNB ;
DR   P0CR18, RPIA_CRYNJ ;  Q0K980, RPIA_CUPNH ;  Q46ZK1, RPIA_CUPPJ ;
DR   B3R1I3, RPIA_CUPTR ;  B8HN58, RPIA_CYAP4 ;  B7KIR2, RPIA_CYAP7 ;
DR   B7K6D3, RPIA_CYAP8 ;  Q6BYI4, RPIA_DEBHA ;  Q9RW24, RPIA_DEIRA ;
DR   B8FL28, RPIA_DESAA ;  Q551C2, RPIA_DICDI ;  A5EVM0, RPIA_DICNV ;
DR   A8LIN0, RPIA_DINSH ;  A7ZR23, RPIA_ECO24 ;  B7UHW1, RPIA_ECO27 ;
DR   B7MM99, RPIA_ECO45 ;  B7LFH2, RPIA_ECO55 ;  P0A7Z2, RPIA_ECO57 ;
DR   B5YQA8, RPIA_ECO5E ;  B7NHX4, RPIA_ECO7I ;  B7MZL0, RPIA_ECO81 ;
DR   B7LYT1, RPIA_ECO8A ;  C5A0I5, RPIA_ECOBW ;  B1XEJ9, RPIA_ECODH ;
DR   A8A454, RPIA_ECOHS ;  A1AFA2, RPIA_ECOK1 ;  Q0TDT9, RPIA_ECOL5 ;
DR   P0A7Z1, RPIA_ECOL6 ;  B1IT89, RPIA_ECOLC ;  P0A7Z0, RPIA_ECOLI ;
DR   B7N7F6, RPIA_ECOLU ;  B6I746, RPIA_ECOSE ;  B1LDB5, RPIA_ECOSM ;
DR   O52398, RPIA_EDWI9 ;  Q8RLY6, RPIA_ENTCL ;  Q839H2, RPIA_ENTFA ;
DR   Q6D093, RPIA_ERWCT ;  B2VF17, RPIA_ERWT9 ;  B7LPC8, RPIA_ESCF3 ;
DR   B1YEE3, RPIA_EXIS2 ;  B0TY81, RPIA_FRAP2 ;  Q14H27, RPIA_FRAT1 ;
DR   A7NBA0, RPIA_FRATF ;  Q2A467, RPIA_FRATH ;  B2SG83, RPIA_FRATM ;
DR   A0Q756, RPIA_FRATN ;  Q5NFM5, RPIA_FRATT ;  A4IYN5, RPIA_FRATW ;
DR   Q7NPM5, RPIA_GLOVI ;  Q5FQ98, RPIA_GLUOX ;  Q7VP95, RPIA_HAEDU ;
DR   Q4QN79, RPIA_HAEI8 ;  A5UA25, RPIA_HAEIE ;  A5UGX5, RPIA_HAEIG ;
DR   P44725, RPIA_HAEIN ;  B8F5R1, RPIA_HAEPS ;  Q0I101, RPIA_HAES1 ;
DR   B0URT3, RPIA_HAES2 ;  Q2SN31, RPIA_HAHCH ;  B9LU09, RPIA_HALLT ;
DR   Q5UZD7, RPIA_HALMA ;  B0R7H0, RPIA_HALS3 ;  Q9HN33, RPIA_HALSA ;
DR   Q18E67, RPIA_HALWD ;  A4G433, RPIA_HERAR ;  P49247, RPIA_HUMAN ;
DR   Q5QVB3, RPIA_IDILO ;  A6T0F1, RPIA_JANMA ;  Q28MH0, RPIA_JANSC ;
DR   B5XUC4, RPIA_KLEP3 ;  A6TDS5, RPIA_KLEP7 ;  Q6CTD5, RPIA_KLULA ;
DR   B1L7D5, RPIA_KORCO ;  Q5FLF6, RPIA_LACAC ;  Q03SV2, RPIA_LACBA ;
DR   Q034H8, RPIA_LACC3 ;  Q1GBA8, RPIA_LACDA ;  Q04BQ8, RPIA_LACDB ;
DR   Q045B8, RPIA_LACGA ;  A8YU42, RPIA_LACH4 ;  Q74KF3, RPIA_LACJO ;
DR   Q9CDI7, RPIA_LACLA ;  A2RP28, RPIA_LACLM ;  Q02VQ6, RPIA_LACLS ;
DR   Q88YY5, RPIA_LACPL ;  A5VI94, RPIA_LACRD ;  B2G5S0, RPIA_LACRJ ;
DR   C1D560, RPIA_LARHH ;  Q5X8Y4, RPIA_LEGPA ;  A5I9R2, RPIA_LEGPC ;
DR   Q5ZZB7, RPIA_LEGPH ;  Q5X0C7, RPIA_LEGPL ;  B1Y3C2, RPIA_LEPCP ;
DR   Q92D46, RPIA_LISIN ;  C1L1P6, RPIA_LISMC ;  Q721J0, RPIA_LISMF ;
DR   Q8Y8D3, RPIA_LISMO ;  A5DXV6, RPIA_LODEL ;  Q65RQ9, RPIA_MANSM ;
DR   A1U689, RPIA_MARAV ;  Q0AR22, RPIA_MARMM ;  A6W2V3, RPIA_MARMS ;
DR   A6UUZ8, RPIA_META3 ;  Q8TQ69, RPIA_METAC ;  A7I6S5, RPIA_METB6 ;
DR   B7L2C9, RPIA_METC4 ;  Q60BV9, RPIA_METCA ;  A9W537, RPIA_METEP ;
DR   Q58998, RPIA_METJA ;  A4FWY7, RPIA_METM5 ;  A9AAC4, RPIA_METM6 ;
DR   A6VGC9, RPIA_METM7 ;  Q8Q0R3, RPIA_METMA ;  Q6LY04, RPIA_METMP ;
DR   B1Z896, RPIA_METPB ;  A2SHQ1, RPIA_METPP ;  B1M272, RPIA_METRJ ;
DR   P72012, RPIA_METTH ;  A6UPJ0, RPIA_METVS ;  P47968, RPIA_MOUSE ;
DR   Q3ITP9, RPIA_NATPD ;  Q5F831, RPIA_NEIG1 ;  B4RL16, RPIA_NEIG2 ;
DR   A9M0U5, RPIA_NEIM0 ;  Q9JTM5, RPIA_NEIMA ;  Q9JYM6, RPIA_NEIMB ;
DR   A1KUU8, RPIA_NEIMF ;  Q82TX6, RPIA_NITEU ;  Q1QN95, RPIA_NITHX ;
DR   Q2YBX7, RPIA_NITMU ;  Q3J7S6, RPIA_NITOC ;  Q3STA8, RPIA_NITWN ;
DR   Q8YYG2, RPIA_NOSS1 ;  B6JE08, RPIA_OLICO ;  A7HS32, RPIA_PARL1 ;
DR   Q6MC00, RPIA_PARUW ;  P57961, RPIA_PASMU ;  C6DF34, RPIA_PECCP ;
DR   Q03E35, RPIA_PEDPA ;  Q7N189, RPIA_PHOLL ;  Q6LMP0, RPIA_PHOPR ;
DR   A5DFH6, RPIA_PICGU ;  A3LP13, RPIA_PICST ;  Q6L1K2, RPIA_PICTO ;
DR   A2TLM1, RPIA_PIG   ;  B1XU95, RPIA_POLNS ;  Q129M0, RPIA_POLSJ ;
DR   A4SYB4, RPIA_POLSQ ;  A2C4N6, RPIA_PROM1 ;  A2C6S4, RPIA_PROM3 ;
DR   A9BCI0, RPIA_PROM4 ;  Q318Q3, RPIA_PROM9 ;  Q7VA25, RPIA_PROMA ;
DR   B4F0Q0, RPIA_PROMH ;  Q7V5N8, RPIA_PROMM ;  Q7V003, RPIA_PROMP ;
DR   Q46J18, RPIA_PROMT ;  Q48CC1, RPIA_PSE14 ;  Q15Q28, RPIA_PSEA6 ;
DR   A6UYD2, RPIA_PSEA7 ;  B7V2P3, RPIA_PSEA8 ;  Q02U86, RPIA_PSEAB ;
DR   Q9I6G1, RPIA_PSEAE ;  Q1I3B8, RPIA_PSEE4 ;  Q4K469, RPIA_PSEF5 ;
DR   C3K3R7, RPIA_PSEFS ;  A5WAL5, RPIA_PSEP1 ;  Q3K535, RPIA_PSEPF ;
DR   B0KP28, RPIA_PSEPG ;  Q88CN0, RPIA_PSEPK ;  B1J2A2, RPIA_PSEPW ;
DR   Q87UK7, RPIA_PSESM ;  Q4ZLU8, RPIA_PSEU2 ;  A4VGK9, RPIA_PSEU5 ;
DR   A1SSJ0, RPIA_PSYIN ;  Q9V0L6, RPIA_PYRAB ;  Q8U1F0, RPIA_PYRFU ;
DR   O50083, RPIA_PYRHO ;  Q5JH26, RPIA_PYRKO ;  B2U9W6, RPIA_RALPJ ;
DR   Q8Y013, RPIA_RALSO ;  B3PPZ4, RPIA_RHIE6 ;  Q2K7M6, RPIA_RHIEC ;
DR   Q1MFT6, RPIA_RHIL3 ;  Q98ML9, RPIA_RHILO ;  B5ZRL6, RPIA_RHILW ;
DR   Q92PB8, RPIA_RHIME ;  C3MDE7, RPIA_RHISN ;  Q21WC3, RPIA_RHOFD ;
DR   Q2IUM8, RPIA_RHOP2 ;  Q07Q53, RPIA_RHOP5 ;  Q6N8C3, RPIA_RHOPA ;
DR   Q216Q6, RPIA_RHOPB ;  Q139E9, RPIA_RHOPS ;  B3QCR0, RPIA_RHOPT ;
DR   A3PL91, RPIA_RHOS1 ;  Q3J101, RPIA_RHOS4 ;  A4WQX2, RPIA_RHOS5 ;
DR   B9KKA1, RPIA_RHOSK ;  A7NNA4, RPIA_ROSCS ;  Q168R5, RPIA_ROSDO ;
DR   A5UXC5, RPIA_ROSS1 ;  A1AVQ5, RPIA_RUTMC ;  Q21F87, RPIA_SACD2 ;
DR   A9MRG2, RPIA_SALAR ;  Q57K52, RPIA_SALCH ;  B5QXJ0, RPIA_SALEP ;
DR   B5RE24, RPIA_SALG2 ;  Q5PJH1, RPIA_SALPA ;  A9N3P6, RPIA_SALPB ;
DR   C0PY37, RPIA_SALPC ;  B5BFM8, RPIA_SALPK ;  P66693, RPIA_SALTI ;
DR   P66692, RPIA_SALTY ;  Q9UTL3, RPIA_SCHPO ;  A1S982, RPIA_SHEAM ;
DR   B8E4U3, RPIA_SHEB2 ;  A3D7R0, RPIA_SHEB5 ;  A6WRS7, RPIA_SHEB8 ;
DR   A9L0P5, RPIA_SHEB9 ;  Q12Q96, RPIA_SHEDO ;  Q086W4, RPIA_SHEFN ;
DR   A3QB49, RPIA_SHELP ;  Q8EHR7, RPIA_SHEON ;  A8H0Q6, RPIA_SHEPA ;
DR   A4Y9L3, RPIA_SHEPC ;  B8CJW7, RPIA_SHEPW ;  A0KTU4, RPIA_SHESA ;
DR   A8FRN6, RPIA_SHESH ;  Q0HLL3, RPIA_SHESM ;  Q0HXZ4, RPIA_SHESR ;
DR   A1RGR8, RPIA_SHESW ;  B1KFT2, RPIA_SHEWM ;  B2U0T0, RPIA_SHIB3 ;
DR   Q31WH4, RPIA_SHIBS ;  Q32BX5, RPIA_SHIDS ;  Q0T0Y5, RPIA_SHIF8 ;
DR   P0A7Z3, RPIA_SHIFL ;  Q3YXV7, RPIA_SHISS ;  Q5LTT5, RPIA_SILPO ;
DR   Q1GF74, RPIA_SILST ;  A6U9T4, RPIA_SINMW ;  Q2NRE0, RPIA_SODGM ;
DR   Q1GX07, RPIA_SPHAL ;  Q5HDM1, RPIA_STAAC ;  P66694, RPIA_STAAM ;
DR   P66695, RPIA_STAAN ;  Q6GE99, RPIA_STAAR ;  Q6G6Y5, RPIA_STAAS ;
DR   P66696, RPIA_STAAW ;  Q5HLQ9, RPIA_STAEQ ;  Q8CRC8, RPIA_STAES ;
DR   Q4L8J6, RPIA_STAHJ ;  Q3K0S0, RPIA_STRA1 ;  Q8E4Y6, RPIA_STRA3 ;
DR   Q8DZC6, RPIA_STRA5 ;  C0M7X6, RPIA_STRE4 ;  B4U3E7, RPIA_STREM ;
DR   A8AXN9, RPIA_STRGC ;  B4SI18, RPIA_STRM5 ;  B2FT30, RPIA_STRMK ;
DR   Q8DTT9, RPIA_STRMU ;  P66697, RPIA_STRP1 ;  Q04L82, RPIA_STRP2 ;
DR   P0DF26, RPIA_STRP3 ;  B5E3K1, RPIA_STRP4 ;  Q5XCL6, RPIA_STRP6 ;
DR   C1C6G3, RPIA_STRP7 ;  Q8P1C5, RPIA_STRP8 ;  Q1JC89, RPIA_STRPB ;
DR   Q1JM73, RPIA_STRPC ;  Q1JHB8, RPIA_STRPD ;  Q1J737, RPIA_STRPF ;
DR   A2RF13, RPIA_STRPG ;  B1IAZ7, RPIA_STRPI ;  B8ZNH8, RPIA_STRPJ ;
DR   Q48U18, RPIA_STRPM ;  Q97RI7, RPIA_STRPN ;  P0DF27, RPIA_STRPQ ;
DR   B5XL07, RPIA_STRPZ ;  Q8DQD1, RPIA_STRR6 ;  A4W2M7, RPIA_STRS2 ;
DR   C0ME44, RPIA_STRS7 ;  A3CNA9, RPIA_STRSV ;  A4VWC6, RPIA_STRSY ;
DR   Q5LZM5, RPIA_STRT1 ;  Q5M481, RPIA_STRT2 ;  Q03KJ8, RPIA_STRTD ;
DR   B9DUK4, RPIA_STRU0 ;  C1CDH6, RPIA_STRZJ ;  C1CJR7, RPIA_STRZP ;
DR   C1CS62, RPIA_STRZT ;  Q2JSC9, RPIA_SYNJA ;  B1XL11, RPIA_SYNP2 ;
DR   Q5N3J1, RPIA_SYNP6 ;  A5GNH7, RPIA_SYNPW ;  Q7U8K8, RPIA_SYNPX ;
DR   A5GVF8, RPIA_SYNR3 ;  Q0I7L2, RPIA_SYNS3 ;  Q3AZA8, RPIA_SYNS9 ;
DR   Q3AHX1, RPIA_SYNSC ;  Q55766, RPIA_SYNY3 ;  C5BMC8, RPIA_TERTT ;
DR   Q9HJT5, RPIA_THEAC ;  Q8DJF2, RPIA_THEEB ;  B9KYD3, RPIA_THERP ;
DR   Q72J47, RPIA_THET2 ;  Q5SIR5, RPIA_THET8 ;  Q97AU2, RPIA_THEVO ;
DR   Q31FB3, RPIA_THICR ;  Q3SGD3, RPIA_THIDA ;  B8GNF8, RPIA_THISH ;
DR   C4L7L6, RPIA_TOLAT ;  Q73M68, RPIA_TREDE ;  O83625, RPIA_TREPA ;
DR   B2S3K6, RPIA_TREPS ;  Q111U2, RPIA_TRIEI ;  Q4P6V4, RPIA_USTMA ;
DR   A7TLF7, RPIA_VANPO ;  A5CXI2, RPIA_VESOH ;  A5F5G0, RPIA_VIBC3 ;
DR   Q9KP93, RPIA_VIBCH ;  C3LR22, RPIA_VIBCM ;  Q5E2Z6, RPIA_VIBF1 ;
DR   B5FAI8, RPIA_VIBFM ;  A7MTQ9, RPIA_VIBHB ;  Q87LL9, RPIA_VIBPA ;
DR   B7VK98, RPIA_VIBSL ;  Q8DC93, RPIA_VIBVU ;  Q7MHL9, RPIA_VIBVY ;
DR   Q8D252, RPIA_WIGBR ;  Q8PH49, RPIA_XANAC ;  Q3BPQ4, RPIA_XANC5 ;
DR   Q4UYA0, RPIA_XANC8 ;  B0RP81, RPIA_XANCB ;  Q8P5S1, RPIA_XANCP ;
DR   Q2P6P9, RPIA_XANOM ;  B2SLM6, RPIA_XANOP ;  Q5H3U0, RPIA_XANOR ;
DR   Q9PBX0, RPIA_XYLFA ;  B0U767, RPIA_XYLFM ;  Q87D89, RPIA_XYLFT ;
DR   Q6CFH4, RPIA_YARLI ;  A6ZNU5, RPIA_YEAS7 ;  Q12189, RPIA_YEAST ;
DR   A1JPP4, RPIA_YERE8 ;  B2K0R4, RPIA_YERPB ;  P37351, RPIB_ECOLI ;
DR   Q7TYI9, RPIB_MYCBO ;  P47636, RPIB_MYCGE ;  Q9CBY1, RPIB_MYCLE ;
DR   Q73XM4, RPIB_MYCPA ;  P53527, RPIB_MYCPN ;  Q79FD7, RPIB_MYCTU ;
//
ID   5.3.1.7
DE   Mannose isomerase.
AN   D-mannose isomerase.
CA   D-mannose = D-fructose.
CC   -!- Also acts on D-lyxose and D-rhamnose.
//
ID   5.3.1.8
DE   Mannose-6-phosphate isomerase.
AN   Phosphohexoisomerase.
AN   Phosphohexomutase.
AN   Phosphomannoisomerase.
AN   Phosphomannose isomerase.
CA   D-mannose 6-phosphate = D-fructose 6-phosphate.
CF   Zinc.
PR   PROSITE; PDOC00746;
DR   P07874, ALGA_PSEAE ;  P59785, ALGA_PSEFL ;  Q88ND5, ALGA_PSEPK ;
DR   Q887Q9, ALGA_PSESM ;  O31646, MANA1_BACSU;  O05511, MANA2_BACSU;
DR   P39841, MANA3_BACSU;  P00946, MANA_ECOLI ;  P29954, MANA_RHIME ;
DR   P25081, MANA_SALTY ;  Q83KZ1, MANA_SHIFL ;  Q59935, MANA_STRMU ;
DR   Q75AB5, MPI_ASHGO  ;  Q66WM4, MPI_ASPFU  ;  Q3SZI0, MPI_BOVIN  ;
DR   P34650, MPI_CAEEL  ;  P34948, MPI_CANAL  ;  Q76IQ2, MPI_CANGA  ;
DR   Q9HFU4, MPI_CRYNJ  ;  Q54PA0, MPI_DICDI  ;  Q9GP38, MPI_ECHMU  ;
DR   P29951, MPI_EMENI  ;  P34949, MPI_HUMAN  ;  Q8HXX2, MPI_MACFA  ;
DR   Q924M7, MPI_MOUSE  ;  Q870Y1, MPI_NEUCR  ;  A5A6K3, MPI_PANTR  ;
DR   Q8J093, MPI_PICAD  ;  Q68FX1, MPI_RAT    ;  O43014, MPI_SCHPO  ;
DR   P29952, MPI_YEAST  ;  Q9YE01, PGMI_AERPE ;  Q44407, PGMI_ANATD ;
DR   O66954, PGMI_AQUAE ;  Q8ZWV0, PGMI_PYRAE ;  Q4JCA7, PGMI_SULAC ;
DR   Q97WE5, PGMI_SULSO ;  Q96YC2, PGMI_SULTO ;  Q9HIC2, PGMI_THEAC ;
DR   Q978F3, PGMI_THEVO ;  B0RVK6, XANB_XANCB ;  P0C7J3, XANB_XANCP ;
//
ID   5.3.1.9
DE   Glucose-6-phosphate isomerase.
AN   Hexose monophosphate isomerase.
AN   Hexosephosphate isomerase.
AN   Oxoisomerase.
AN   Phosphoglucoisomerase.
AN   Phosphoglucose isomerase.
AN   Phosphohexoisomerase.
AN   Phosphohexomutase.
AN   Phosphohexose isomerase.
AN   Phosphosaccharomutase.
CA   D-glucose 6-phosphate = D-fructose 6-phosphate.
CC   -!- Also catalyzes the anomerization of D-glucose 6-phosphate.
PR   PROSITE; PDOC00157;
DR   Q1QZ19, G6PI1_CHRSD;  Q7P1R4, G6PI1_CHRVO;  P54234, G6PI1_CLAAR;
DR   P54235, G6PI1_CLACO;  P54236, G6PI1_CLAFR;  P34796, G6PI1_CLALE;
DR   P54237, G6PI1_CLAMI;  P54238, G6PI1_CLARO;  P54239, G6PI1_CLAWI;
DR   P54240, G6PI1_CLAXA;  Q487J6, G6PI1_COLP3;  Q472C7, G6PI1_CUPPJ;
DR   Q5F8P8, G6PI1_NEIG1;  Q9JTW1, G6PI1_NEIMA;  Q9JYX3, G6PI1_NEIMB;
DR   Q88LW9, G6PI1_PSEPK;  Q92MQ8, G6PI1_RHIME;  Q0S539, G6PI1_RHOSR;
DR   Q82M90, G6PI1_STRAW;  O88015, G6PI1_STRCO;  Q3SK65, G6PI1_THIDA;
DR   Q1QUG5, G6PI2_CHRSD;  Q7NVH4, G6PI2_CHRVO;  P54241, G6PI2_CLACO;
DR   P29333, G6PI2_CLALE;  P54242, G6PI2_CLAXA;  Q483D3, G6PI2_COLP3;
DR   Q471B8, G6PI2_CUPPJ;  Q5F694, G6PI2_NEIG1;  Q9JSS6, G6PI2_NEIMA;
DR   Q9K153, G6PI2_NEIMB;  Q88DW7, G6PI2_PSEPK;  Q92UI1, G6PI2_RHIME;
DR   Q0RVH6, G6PI2_RHOSR;  Q829V7, G6PI2_STRAW;  Q9Z523, G6PI2_STRCO;
DR   Q3SH73, G6PI2_THIDA;  P34797, G6PI3_CLALE;  Q0RV72, G6PI3_RHOSR;
DR   Q0RUR2, G6PI4_RHOSR;  P13375, G6PIA_GEOSE;  P42862, G6PIA_ORYSJ;
DR   P13376, G6PIB_GEOSE;  P42863, G6PIB_ORYSJ;  B0CCT9, G6PI_ACAM1 ;
DR   A9NHX0, G6PI_ACHLI ;  Q59088, G6PI_ACIAD ;  B7H2H4, G6PI_ACIB3 ;
DR   B7IBR9, G6PI_ACIB5 ;  B2I056, G6PI_ACIBC ;  B0VMS2, G6PI_ACIBS ;
DR   A3M0W5, G6PI_ACIBT ;  B0V6J2, G6PI_ACIBY ;  Q9RMC1, G6PI_ACILW ;
DR   A3N1E1, G6PI_ACTP2 ;  B3GY24, G6PI_ACTP7 ;  B0BQ77, G6PI_ACTPJ ;
DR   A0KEM2, G6PI_AERHH ;  A4STE1, G6PI_AERS4 ;  Q711G1, G6PI_AGABI ;
DR   B9J8H9, G6PI_AGRRK ;  Q8UI94, G6PI_AGRT5 ;  B9JQW4, G6PI_AGRVS ;
DR   Q0VR14, G6PI_ALCBS ;  B6ELK8, G6PI_ALISL ;  A6TN07, G6PI_ALKMQ ;
DR   B4RX41, G6PI_ALTMD ;  B8JGW9, G6PI_ANAD2 ;  Q2IE39, G6PI_ANADE ;
DR   B4ULW4, G6PI_ANASK ;  Q3M6S3, G6PI_ANAVT ;  Q9FXM5, G6PI_ARAGE ;
DR   Q9FXM4, G6PI_ARALP ;  P34795, G6PI_ARATH ;  Q5P0T4, G6PI_AROAE ;
DR   Q758L0, G6PI_ASHGO ;  Q9HGZ2, G6PI_ASPOR ;  Q2NJ38, G6PI_AYWBP ;
DR   A7Z848, G6PI_BACA2 ;  A0RK94, G6PI_BACAH ;  Q81K75, G6PI_BACAN ;
DR   B7JDF6, G6PI_BACC0 ;  Q72YI4, G6PI_BACC1 ;  B7IMR7, G6PI_BACC2 ;
DR   B7HBD4, G6PI_BACC4 ;  B7HTY6, G6PI_BACC7 ;  A7GUA6, G6PI_BACCN ;
DR   Q816G0, G6PI_BACCR ;  Q632G4, G6PI_BACCZ ;  Q5L9E3, G6PI_BACFN ;
DR   Q64PM7, G6PI_BACFR ;  Q9K7L8, G6PI_BACHD ;  Q6HC08, G6PI_BACHK ;
DR   Q65FL6, G6PI_BACLD ;  A8FGU0, G6PI_BACP2 ;  Q5WDX0, G6PI_BACSK ;
DR   P80860, G6PI_BACSU ;  Q8A5W2, G6PI_BACTN ;  A6L7P7, G6PI_BACV8 ;
DR   A9VMW5, G6PI_BACWK ;  A1URM5, G6PI_BARBK ;  Q8L1Z9, G6PI_BARHE ;
DR   Q6G0T9, G6PI_BARQU ;  Q1LU73, G6PI_BAUCH ;  B2IJT2, G6PI_BEII9 ;
DR   Q8G7I6, G6PI_BIFLO ;  Q7VRI4, G6PI_BLOFL ;  Q491V0, G6PI_BLOPB ;
DR   Q2KYE9, G6PI_BORA1 ;  Q0SMC6, G6PI_BORAP ;  Q7WP01, G6PI_BORBR ;
DR   O51672, G6PI_BORBU ;  B7J0H6, G6PI_BORBZ ;  Q660E3, G6PI_BORGA ;
DR   Q7W197, G6PI_BORPA ;  A9I734, G6PI_BORPD ;  Q7VUF4, G6PI_BORPE ;
DR   Q3ZBD7, G6PI_BOVIN ;  B2S928, G6PI_BRUA1 ;  Q2YPF3, G6PI_BRUA2 ;
DR   Q57F73, G6PI_BRUAB ;  A9M7X1, G6PI_BRUC2 ;  C0RH03, G6PI_BRUMB ;
DR   Q8YF86, G6PI_BRUME ;  A5VNM7, G6PI_BRUO2 ;  B0CJR3, G6PI_BRUSI ;
DR   Q8G2N3, G6PI_BRUSU ;  B8D8D7, G6PI_BUCA5 ;  P57636, G6PI_BUCAI ;
DR   Q8K910, G6PI_BUCAP ;  B8D894, G6PI_BUCAT ;  Q89A35, G6PI_BUCBP ;
DR   Q056X6, G6PI_BUCCC ;  B1YRY9, G6PI_BURA4 ;  Q1BH79, G6PI_BURCA ;
DR   B1JTU4, G6PI_BURCC ;  B4EBL7, G6PI_BURCJ ;  A9AJR8, G6PI_BURM1 ;
DR   A3MKI3, G6PI_BURM7 ;  A2SBH6, G6PI_BURM9 ;  Q62JL8, G6PI_BURMA ;
DR   A1V4V8, G6PI_BURMS ;  A3NW90, G6PI_BURP0 ;  Q3JRE2, G6PI_BURP1 ;
DR   A3NAH2, G6PI_BURP6 ;  B2JGM3, G6PI_BURP8 ;  B2T411, G6PI_BURPP ;
DR   Q63V31, G6PI_BURPS ;  Q39FF4, G6PI_BURS3 ;  Q2SWP6, G6PI_BURTA ;
DR   Q13Z07, G6PI_BURXL ;  P46479, G6PI_CALFI ;  A7H491, G6PI_CAMJD ;
DR   Q9PMD4, G6PI_CAMJE ;  P83780, G6PI_CANAL ;  Q6FRW1, G6PI_CANGA ;
DR   Q3AFH3, G6PI_CARHZ ;  B8GY92, G6PI_CAUCN ;  Q9ABK5, G6PI_CAUCR ;
DR   B0T2Y6, G6PI_CAUSK ;  Q5L5E1, G6PI_CHLAB ;  Q3ASZ0, G6PI_CHLCH ;
DR   Q822E7, G6PI_CHLCV ;  Q255I6, G6PI_CHLFF ;  Q9PK16, G6PI_CHLMU ;
DR   A1BFF9, G6PI_CHLPD ;  Q9Z6N4, G6PI_CHLPN ;  B0B7U7, G6PI_CHLT2 ;
DR   Q3KLX6, G6PI_CHLTA ;  B0BC12, G6PI_CHLTB ;  Q8KDQ7, G6PI_CHLTE ;
DR   P0CD72, G6PI_CHLTR ;  A8ANA6, G6PI_CITK8 ;  Q97FP8, G6PI_CLOAB ;
DR   A7FYM5, G6PI_CLOB1 ;  A6LQ99, G6PI_CLOB8 ;  B2UZ17, G6PI_CLOBA ;
DR   B2TIZ1, G6PI_CLOBB ;  A5I705, G6PI_CLOBH ;  B1ING9, G6PI_CLOBK ;
DR   A7GIL4, G6PI_CLOBL ;  B1L1I1, G6PI_CLOBM ;  Q180C9, G6PI_CLOD6 ;
DR   A0Q2R0, G6PI_CLONN ;  Q0TN51, G6PI_CLOP1 ;  Q8XI54, G6PI_CLOPE ;
DR   A9KHD9, G6PI_CLOPH ;  Q0SQS9, G6PI_CLOPS ;  Q891H2, G6PI_CLOTE ;
DR   A3DBX9, G6PI_CLOTH ;  Q6NIE5, G6PI_CORDI ;  Q8FR39, G6PI_COREF ;
DR   A4QCJ4, G6PI_CORGB ;  Q8NS31, G6PI_CORGL ;  Q4JX51, G6PI_CORJK ;
DR   C4LHE0, G6PI_CORK4 ;  B6J6S3, G6PI_COXB1 ;  B6J0K9, G6PI_COXB2 ;
DR   A9KFK2, G6PI_COXBN ;  A9ND66, G6PI_COXBR ;  Q83D91, G6PI_COXBU ;
DR   P50309, G6PI_CRIGR ;  B3R508, G6PI_CUPTR ;  B8HVV6, G6PI_CYAP4 ;
DR   B7KJ74, G6PI_CYAP7 ;  B7JUF5, G6PI_CYAP8 ;  Q47IJ3, G6PI_DECAR ;
DR   C1CWW2, G6PI_DEIDV ;  Q1IYT4, G6PI_DEIGD ;  Q9RTL8, G6PI_DEIRA ;
DR   B8FK51, G6PI_DESAA ;  C0QL01, G6PI_DESAH ;  B8G1G1, G6PI_DESHD ;
DR   Q24VW9, G6PI_DESHY ;  C4XST3, G6PI_DESMR ;  A8ZSB6, G6PI_DESOH ;
DR   Q6AQ48, G6PI_DESPS ;  Q5V9E9, G6PI_DICDI ;  P52029, G6PI_DROME ;
DR   P52030, G6PI_DROSI ;  P52031, G6PI_DROYA ;  A7ZUP3, G6PI_ECO24 ;
DR   B7UPI6, G6PI_ECO27 ;  B7MJ15, G6PI_ECO45 ;  B7LAX0, G6PI_ECO55 ;
DR   P0A6T2, G6PI_ECO57 ;  B5Z0C4, G6PI_ECO5E ;  B7NRZ0, G6PI_ECO7I ;
DR   B7MRF7, G6PI_ECO81 ;  B7M7T4, G6PI_ECO8A ;  C5A0W2, G6PI_ECOBW ;
DR   B1XC24, G6PI_ECODH ;  A8A7C4, G6PI_ECOHS ;  A1AIK3, G6PI_ECOK1 ;
DR   Q0TA36, G6PI_ECOL5 ;  Q8FB44, G6PI_ECOL6 ;  B1IUM7, G6PI_ECOLC ;
DR   P0A6T1, G6PI_ECOLI ;  B7NFW8, G6PI_ECOLU ;  B6I5N7, G6PI_ECOSE ;
DR   B1LPI9, G6PI_ECOSM ;  Q1R3R3, G6PI_ECOUT ;  C5B6Z1, G6PI_EDWI9 ;
DR   Q8SRY1, G6PI_ENCCU ;  A4W5E0, G6PI_ENT38 ;  Q835G1, G6PI_ENTFA ;
DR   A7MPC2, G6PI_ENTS8 ;  Q6D022, G6PI_ERWCT ;  B2VKB1, G6PI_ERWT9 ;
DR   Q2NB79, G6PI_ERYLH ;  B7LKZ8, G6PI_ESCF3 ;  B1YKI7, G6PI_EXIS2 ;
DR   B0TYL4, G6PI_FRAP2 ;  Q2JH03, G6PI_FRASC ;  Q14GS7, G6PI_FRAT1 ;
DR   A7NDI3, G6PI_FRATF ;  Q2A2C5, G6PI_FRATH ;  B2SDF7, G6PI_FRATM ;
DR   A0Q5P0, G6PI_FRATN ;  Q0BKZ2, G6PI_FRATO ;  Q5NFC4, G6PI_FRATT ;
DR   A4IZ54, G6PI_FRATW ;  Q8RHH5, G6PI_FUSNN ;  B5EBB8, G6PI_GEOBB ;
DR   Q5KVS7, G6PI_GEOKA ;  Q39SU1, G6PI_GEOMG ;  B9M5A2, G6PI_GEOSF ;
DR   Q74DK5, G6PI_GEOSL ;  C6E5H7, G6PI_GEOSM ;  A4ISB8, G6PI_GEOTN ;
DR   A5G7Y7, G6PI_GEOUR ;  Q7NJY9, G6PI_GLOVI ;  A0M665, G6PI_GRAFK ;
DR   Q7VNR9, G6PI_HAEDU ;  Q4QL07, G6PI_HAEI8 ;  A5UCG6, G6PI_HAEIE ;
DR   A5UED2, G6PI_HAEIG ;  P44312, G6PI_HAEIN ;  B8F632, G6PI_HAEPS ;
DR   Q0I3C7, G6PI_HAES1 ;  B0UUD4, G6PI_HAES2 ;  Q2S8W1, G6PI_HAHCH ;
DR   Q5UXU0, G6PI_HALMA ;  Q9HNQ6, G6PI_HALSA ;  Q18FQ4, G6PI_HALWD ;
DR   C4K8I7, G6PI_HAMD5 ;  Q17W92, G6PI_HELAH ;  B0TGL6, G6PI_HELMI ;
DR   B6JN06, G6PI_HELP2 ;  B5Z8G1, G6PI_HELPG ;  Q1CSA0, G6PI_HELPH ;
DR   Q9ZK49, G6PI_HELPJ ;  B2UUS4, G6PI_HELPS ;  O25781, G6PI_HELPY ;
DR   P06744, G6PI_HUMAN ;  Q5QWW0, G6PI_IDILO ;  Q28QX4, G6PI_JANSC ;
DR   P77877, G6PI_KLEOX ;  B5XY03, G6PI_KLEP3 ;  A6TGT4, G6PI_KLEP7 ;
DR   P12341, G6PI_KLULA ;  Q5FL04, G6PI_LACAC ;  Q03QV7, G6PI_LACBA ;
DR   Q03A55, G6PI_LACC3 ;  B3WDC0, G6PI_LACCB ;  Q1GAY0, G6PI_LACDA ;
DR   Q83XM3, G6PI_LACFE ;  Q042K0, G6PI_LACGA ;  A8YUI5, G6PI_LACH4 ;
DR   Q74K31, G6PI_LACJO ;  P81181, G6PI_LACLA ;  A2RNW8, G6PI_LACLM ;
DR   Q02VW5, G6PI_LACLS ;  Q88UI4, G6PI_LACPL ;  A5VIL5, G6PI_LACRD ;
DR   B2G649, G6PI_LACRJ ;  Q1WUR2, G6PI_LACS1 ;  Q38WF1, G6PI_LACSS ;
DR   C1DAI5, G6PI_LARHH ;  Q5X6Y8, G6PI_LEGPA ;  Q5ZXH2, G6PI_LEGPH ;
DR   Q5WYE0, G6PI_LEGPL ;  Q9RDY2, G6PI_LEGPN ;  P42861, G6PI_LEIME ;
DR   B0S9I4, G6PI_LEPBA ;  Q04UY8, G6PI_LEPBJ ;  Q04YI9, G6PI_LEPBL ;
DR   B0SJQ8, G6PI_LEPBP ;  B1Y2Y7, G6PI_LEPCP ;  Q72MT7, G6PI_LEPIC ;
DR   Q8EZG6, G6PI_LEPIN ;  B1MX40, G6PI_LEUCK ;  Q03Z94, G6PI_LEUMM ;
DR   Q928R6, G6PI_LISIN ;  Q71X61, G6PI_LISMF ;  Q8Y4R7, G6PI_LISMO ;
DR   A0AL52, G6PI_LISW6 ;  Q4R591, G6PI_MACFA ;  Q2VYV7, G6PI_MAGSA ;
DR   A0L900, G6PI_MAGSM ;  P49105, G6PI_MAIZE ;  Q65TC2, G6PI_MANSM ;
DR   A6W2I5, G6PI_MARMS ;  Q6F1L2, G6PI_MESFL ;  Q11MA0, G6PI_MESSB ;
DR   Q609I7, G6PI_METCA ;  Q1H1P4, G6PI_METFK ;  Q59000, G6PI_METJA ;
DR   Q6LXQ4, G6PI_METMP ;  A2SKF8, G6PI_METPP ;  B8ENL8, G6PI_METSB ;
DR   B0JVE7, G6PI_MICAN ;  P06745, G6PI_MOUSE ;  A0QBN4, G6PI_MYCA1 ;
DR   P64193, G6PI_MYCBO ;  A1KH80, G6PI_MYCBP ;  C1ALT2, G6PI_MYCBT ;
DR   Q2SS24, G6PI_MYCCT ;  Q9KX58, G6PI_MYCGA ;  P47357, G6PI_MYCGE ;
DR   A4T6W8, G6PI_MYCGI ;  Q600A8, G6PI_MYCH2 ;  Q4A7J2, G6PI_MYCH7 ;
DR   Q4A9F3, G6PI_MYCHJ ;  B8ZTZ5, G6PI_MYCLB ;  Q9CD75, G6PI_MYCLE ;
DR   B2HED8, G6PI_MYCMM ;  Q6KH90, G6PI_MYCMO ;  Q6MTA3, G6PI_MYCMS ;
DR   Q742E4, G6PI_MYCPA ;  Q8EVU1, G6PI_MYCPE ;  P78033, G6PI_MYCPN ;
DR   Q98R79, G6PI_MYCPU ;  A0R3N9, G6PI_MYCS2 ;  Q4A5S9, G6PI_MYCS5 ;
DR   P96803, G6PI_MYCSM ;  A5U0Y6, G6PI_MYCTA ;  P64192, G6PI_MYCTU ;
DR   A0PVN7, G6PI_MYCUA ;  A1TEQ0, G6PI_MYCVP ;  Q1CX51, G6PI_MYXXD ;
DR   Q3IMS0, G6PI_NATPD ;  Q7S986, G6PI_NEUCR ;  Q82SP4, G6PI_NITEU ;
DR   Q2YBU4, G6PI_NITMU ;  Q3JCN1, G6PI_NITOC ;  Q5YPP1, G6PI_NOCFA ;
DR   B2J5F1, G6PI_NOSP7 ;  Q8YY05, G6PI_NOSS1 ;  Q2G7C4, G6PI_NOVAD ;
DR   Q8ENY8, G6PI_OCEIH ;  A6WVU6, G6PI_OCHA4 ;  P54243, G6PI_OENME ;
DR   Q04G44, G6PI_OENOB ;  Q6YQU0, G6PI_ONYPE ;  A6L8C4, G6PI_PARD8 ;
DR   Q6MD44, G6PI_PARUW ;  Q9CNL2, G6PI_PASMU ;  C6DFP4, G6PI_PECCP ;
DR   Q03EI3, G6PI_PEDPA ;  Q3A201, G6PI_PELCD ;  Q3B3Q8, G6PI_PELLD ;
DR   Q7MZB4, G6PI_PHOLL ;  Q6LM51, G6PI_PHOPR ;  P08059, G6PI_PIG   ;
DR   P18240, G6PI_PLAFA ;  A1VJZ6, G6PI_POLNA ;  Q5R4E3, G6PI_PONAB ;
DR   Q7MUV9, G6PI_PORGI ;  Q6A5X5, G6PI_PROAC ;  A3PCW7, G6PI_PROM0 ;
DR   A2C241, G6PI_PROM1 ;  A8G4T6, G6PI_PROM2 ;  A9BAE3, G6PI_PROM4 ;
DR   A2BWL8, G6PI_PROM5 ;  Q31AX5, G6PI_PROM9 ;  Q7VBZ6, G6PI_PROMA ;
DR   B4EYR8, G6PI_PROMH ;  Q7V7M6, G6PI_PROMM ;  Q7V1I1, G6PI_PROMP ;
DR   A2BR44, G6PI_PROMS ;  Q46L16, G6PI_PROMT ;  Q48N88, G6PI_PSE14 ;
DR   Q15PR3, G6PI_PSEA6 ;  A6VCI8, G6PI_PSEA7 ;  B7V1E4, G6PI_PSEA8 ;
DR   Q02FU0, G6PI_PSEAB ;  Q9HV67, G6PI_PSEAE ;  Q1I4P0, G6PI_PSEE4 ;
DR   Q4K5Y1, G6PI_PSEF5 ;  Q848I4, G6PI_PSEFL ;  C3K249, G6PI_PSEFS ;
DR   Q3IKH4, G6PI_PSEHT ;  A4XYC6, G6PI_PSEMY ;  A5W976, G6PI_PSEP1 ;
DR   Q3K6Q4, G6PI_PSEPF ;  B0KHW6, G6PI_PSEPG ;  B1J2C0, G6PI_PSEPW ;
DR   Q888Q7, G6PI_PSESM ;  Q4ZY88, G6PI_PSEU2 ;  A4VPM9, G6PI_PSEU5 ;
DR   Q4FVH5, G6PI_PSYA2 ;  Q1QEK1, G6PI_PSYCK ;  A1SRS5, G6PI_PSYIN ;
DR   Q9UXW3, G6PI_PYRAB ;  P83194, G6PI_PYRFU ;  O59618, G6PI_PYRHO ;
DR   Q9N1E2, G6PI_RABIT ;  Q1LM68, G6PI_RALME ;  B2UF65, G6PI_RALPJ ;
DR   Q8XYN9, G6PI_RALSO ;  Q6P6V0, G6PI_RAT   ;  B3Q0A9, G6PI_RHIE6 ;
DR   Q2KCY8, G6PI_RHIEC ;  Q1MM06, G6PI_RHIL3 ;  Q98BV5, G6PI_RHILO ;
DR   B5ZNS9, G6PI_RHILW ;  Q92SC4, G6PI_RHIME ;  Q21ZD5, G6PI_RHOFD ;
DR   C1AWW0, G6PI_RHOOB ;  Q2RQ51, G6PI_RHORT ;  A3PJI8, G6PI_RHOS1 ;
DR   Q3J2U4, G6PI_RHOS4 ;  A4WTF5, G6PI_RHOS5 ;  B9KRX7, G6PI_RHOSK ;
DR   A7NH85, G6PI_ROSCS ;  Q165T7, G6PI_ROSDO ;  A5V1D8, G6PI_ROSS1 ;
DR   Q1ASN4, G6PI_RUBXD ;  Q21M11, G6PI_SACD2 ;  B5F1P0, G6PI_SALA4 ;
DR   A9MHA7, G6PI_SALAR ;  Q57H06, G6PI_SALCH ;  B5FQP5, G6PI_SALDC ;
DR   B5QYI4, G6PI_SALEP ;  B5R7S0, G6PI_SALG2 ;  B4TDK4, G6PI_SALHS ;
DR   B4T1R5, G6PI_SALNS ;  Q5PL07, G6PI_SALPA ;  A9N1J6, G6PI_SALPB ;
DR   C0Q4C6, G6PI_SALPC ;  B5BJU4, G6PI_SALPK ;  B4TQN8, G6PI_SALSV ;
DR   Q8Z1U7, G6PI_SALTI ;  Q8ZKI4, G6PI_SALTY ;  P78917, G6PI_SCHPO ;
DR   A8GKD1, G6PI_SERP5 ;  A1S413, G6PI_SHEAM ;  B8EFD8, G6PI_SHEB2 ;
DR   A3D1F4, G6PI_SHEB5 ;  A6WKC3, G6PI_SHEB8 ;  A9L4T5, G6PI_SHEB9 ;
DR   Q12KL2, G6PI_SHEDO ;  Q07Z24, G6PI_SHEFN ;  B0TJ99, G6PI_SHEHH ;
DR   A3QBW1, G6PI_SHELP ;  Q8EBH1, G6PI_SHEON ;  A8H1G3, G6PI_SHEPA ;
DR   A4Y493, G6PI_SHEPC ;  B8CSD4, G6PI_SHEPW ;  A0L003, G6PI_SHESA ;
DR   A8FSH2, G6PI_SHESH ;  Q0HFX8, G6PI_SHESM ;  Q0HS71, G6PI_SHESR ;
DR   A1RMN7, G6PI_SHESW ;  B1KIS3, G6PI_SHEWM ;  B2TX50, G6PI_SHIB3 ;
DR   Q31TX1, G6PI_SHIBS ;  Q328X7, G6PI_SHIDS ;  Q0SXP3, G6PI_SHIF8 ;
DR   Q83IN9, G6PI_SHIFL ;  Q3YUW0, G6PI_SHISS ;  Q5LRS9, G6PI_SILPO ;
DR   Q1GJQ5, G6PI_SILST ;  A6U5N9, G6PI_SINMW ;  Q2NR04, G6PI_SODGM ;
DR   Q1GTU1, G6PI_SPHAL ;  A5V9W3, G6PI_SPHWW ;  O82059, G6PI_SPIOL ;
DR   A7X0H6, G6PI_STAA1 ;  Q2FIB3, G6PI_STAA3 ;  Q2FZU0, G6PI_STAA8 ;
DR   Q2YWS3, G6PI_STAAB ;  Q5HHC2, G6PI_STAAC ;  A6QFH3, G6PI_STAAE ;
DR   P64194, G6PI_STAAM ;  P99078, G6PI_STAAN ;  Q6GIC6, G6PI_STAAR ;
DR   Q6GAW4, G6PI_STAAS ;  Q8NXF1, G6PI_STAAW ;  Q5HQJ9, G6PI_STAEQ ;
DR   Q8CT80, G6PI_STAES ;  Q4L4X8, G6PI_STAHJ ;  Q49WA1, G6PI_STAS1 ;
DR   Q3K2Y2, G6PI_STRA1 ;  P64195, G6PI_STRA3 ;  P64196, G6PI_STRA5 ;
DR   B4U0D8, G6PI_STREM ;  A8AUL5, G6PI_STRGC ;  B1W0Z7, G6PI_STRGG ;
DR   B4SRY7, G6PI_STRM5 ;  B2FL71, G6PI_STRMK ;  Q9X670, G6PI_STRMU ;
DR   Q9A1L1, G6PI_STRP1 ;  Q04IA2, G6PI_STRP2 ;  P0DB24, G6PI_STRP3 ;
DR   B5E379, G6PI_STRP4 ;  Q5XE09, G6PI_STRP6 ;  Q8P2R3, G6PI_STRP8 ;
DR   Q1JDQ8, G6PI_STRPB ;  Q1JNM4, G6PI_STRPC ;  Q1JIS1, G6PI_STRPD ;
DR   Q1J8N2, G6PI_STRPF ;  A2RCD9, G6PI_STRPG ;  B1I9D8, G6PI_STRPI ;
DR   Q48VF9, G6PI_STRPM ;  Q97NG0, G6PI_STRPN ;  P0DB25, G6PI_STRPQ ;
DR   B2IMZ0, G6PI_STRPS ;  B5XJM0, G6PI_STRPZ ;  Q8DN74, G6PI_STRR6 ;
DR   Q5M1N9, G6PI_STRT1 ;  Q8VVB7, G6PI_STRT2 ;  Q03ML5, G6PI_STRTD ;
DR   Q67QQ0, G6PI_SYMTH ;  Q2LRD0, G6PI_SYNAS ;  Q31LL0, G6PI_SYNE7 ;
DR   A0LPA9, G6PI_SYNFM ;  Q2JX86, G6PI_SYNJA ;  Q2JHU0, G6PI_SYNJB ;
DR   Q5N0B4, G6PI_SYNP6 ;  Q7U6T0, G6PI_SYNPX ;  Q3AXV8, G6PI_SYNS9 ;
DR   Q3AJU7, G6PI_SYNSC ;  P52983, G6PI_SYNY3 ;  Q8DKY2, G6PI_THEEB ;
DR   P84140, G6PI_THELI ;  Q9X1A5, G6PI_THEMA ;  B0K7V7, G6PI_THEP3 ;
DR   B0K6M6, G6PI_THEPX ;  Q72GY6, G6PI_THET2 ;  Q5SLL6, G6PI_THET8 ;
DR   Q8R924, G6PI_THETN ;  Q31I19, G6PI_THICR ;  C4L8P1, G6PI_TOLAT ;
DR   Q73K18, G6PI_TREDE ;  O83488, G6PI_TREPA ;  B2S370, G6PI_TREPS ;
DR   P13377, G6PI_TRYBB ;  B1H069, G6PI_UNCTG ;  A5F3J3, G6PI_VIBC3 ;
DR   Q9KUY4, G6PI_VIBCH ;  C3LRA6, G6PI_VIBCM ;  Q5E847, G6PI_VIBF1 ;
DR   B5FGI2, G6PI_VIBFM ;  A7MSY9, G6PI_VIBHB ;  Q87L81, G6PI_VIBPA ;
DR   B7VI73, G6PI_VIBSL ;  Q8DCK7, G6PI_VIBVU ;  Q7MH97, G6PI_VIBVY ;
DR   Q8D1V8, G6PI_WIGBR ;  P0A0T0, G6PI_XANAC ;  Q3BUL3, G6PI_XANC5 ;
DR   Q4UTV8, G6PI_XANC8 ;  B0RTT8, G6PI_XANCB ;  P0A0T1, G6PI_XANCI ;
DR   Q8P9S7, G6PI_XANCP ;  Q2P380, G6PI_XANOM ;  B2SJM1, G6PI_XANOP ;
DR   Q5H0A7, G6PI_XANOR ;  A7IEQ6, G6PI_XANP2 ;  B2I723, G6PI_XYLF2 ;
DR   Q9PGR6, G6PI_XYLFA ;  B0U1Q5, G6PI_XYLFM ;  Q87EV7, G6PI_XYLFT ;
DR   P12709, G6PI_YEAST ;  A1JRV9, G6PI_YERE8 ;  A7FDG8, G6PI_YERP3 ;
DR   Q1CC27, G6PI_YERPA ;  B2K4Y6, G6PI_YERPB ;  Q8ZAS2, G6PI_YERPE ;
DR   A9R536, G6PI_YERPG ;  Q1CNS4, G6PI_YERPN ;  A4TH39, G6PI_YERPP ;
DR   Q664W9, G6PI_YERPS ;  B1JJM7, G6PI_YERPY ;  P28718, G6PI_ZYMMO ;
DR   Q5JE38, GPI_PYRKO  ;  A6UCB5, GPI_SINMW  ;  C5A5R8, GPI_THEGJ  ;
DR   B6YT45, GPI_THEON  ;  Q9YE01, PGMI_AERPE ;  Q44407, PGMI_ANATD ;
DR   O66954, PGMI_AQUAE ;  Q8ZWV0, PGMI_PYRAE ;  Q4JCA7, PGMI_SULAC ;
DR   Q97WE5, PGMI_SULSO ;  Q96YC2, PGMI_SULTO ;  Q9HIC2, PGMI_THEAC ;
DR   Q978F3, PGMI_THEVO ;
//
ID   5.3.1.10
DE   Transferred entry: 3.5.99.6.
//
ID   5.3.1.11
DE   Deleted entry.
//
ID   5.3.1.12
DE   Glucuronate isomerase.
AN   D-glucuronate isomerase.
AN   Uronate isomerase.
AN   Uronic acid isomerase.
AN   Uronic isomerase.
CA   D-glucuronate = D-fructuronate.
CC   -!- Also converts D-galacturonate to D-tagaturonate.
DR   A6VKM8, UXAC_ACTSZ ;  B9MS46, UXAC_ANATD ;  A7Z3M5, UXAC_BACA2 ;
DR   Q5LCT3, UXAC_BACFN ;  Q64TY9, UXAC_BACFR ;  Q9KEZ4, UXAC_BACHD ;
DR   Q65F21, UXAC_BACLD ;  A8FHC4, UXAC_BACP2 ;  Q5WJC1, UXAC_BACSK ;
DR   O34808, UXAC_BACSU ;  Q8A9J2, UXAC_BACTN ;  A6L4U4, UXAC_BACV8 ;
DR   C0QWA9, UXAC_BRAHW ;  A9MC99, UXAC_BRUC2 ;  Q8YCQ2, UXAC_BRUME ;
DR   A9WZA1, UXAC_BRUSI ;  Q8FVM4, UXAC_BRUSU ;  A4XKU9, UXAC_CALS8 ;
DR   B8H5V4, UXAC_CAUCN ;  Q9A874, UXAC_CAUCR ;  B3PBK5, UXAC_CELJU ;
DR   Q97L70, UXAC_CLOAB ;  Q8XP14, UXAC_CLOPE ;  A9KNI7, UXAC_CLOPH ;
DR   Q8FMX2, UXAC_COREF ;  Q8NMT1, UXAC_CORGL ;  A7ZRX6, UXAC_ECO24 ;
DR   B7UIZ9, UXAC_ECO27 ;  B7MB25, UXAC_ECO45 ;  B7LH20, UXAC_ECO55 ;
DR   Q8XAI7, UXAC_ECO57 ;  B5YRY4, UXAC_ECO5E ;  B7NJV5, UXAC_ECO7I ;
DR   B7N095, UXAC_ECO81 ;  B7LZZ6, UXAC_ECO8A ;  C4ZR08, UXAC_ECOBW ;
DR   B1XG96, UXAC_ECODH ;  A8A4Q0, UXAC_ECOHS ;  A1AG09, UXAC_ECOK1 ;
DR   Q0TD14, UXAC_ECOL5 ;  P0A8G4, UXAC_ECOL6 ;  B1IRM5, UXAC_ECOLC ;
DR   P0A8G3, UXAC_ECOLI ;  B7ND80, UXAC_ECOLU ;  B6I464, UXAC_ECOSE ;
DR   B1LFJ0, UXAC_ECOSM ;  C5BH54, UXAC_EDWI9 ;  A7MIR9, UXAC_ENTS8 ;
DR   Q6D9H0, UXAC_ERWCT ;  B7LMX3, UXAC_ESCF3 ;  C4Z5P8, UXAC_EUBE2 ;
DR   A5FC03, UXAC_FLAJ1 ;  Q9ZFL8, UXAC_GEOSE ;  A4IP75, UXAC_GEOTN ;
DR   Q4QPJ6, UXAC_HAEI8 ;  A5UFL7, UXAC_HAEIG ;  B0URH4, UXAC_HAES2 ;
DR   B5XTW7, UXAC_KLEP3 ;  Q9CF53, UXAC_LACLA ;  A2RJK5, UXAC_LACLM ;
DR   Q02XT4, UXAC_LACLS ;  Q38ZF1, UXAC_LACSS ;  Q65V59, UXAC_MANSM ;
DR   A6VZ14, UXAC_MARMS ;  Q9KHA1, UXAC_NOSP7 ;  Q8CXN4, UXAC_OCEIH ;
DR   B1ZP77, UXAC_OPITP ;  C6DKE7, UXAC_PECCP ;  B4RGF5, UXAC_PHEZH ;
DR   Q7N9X5, UXAC_PHOLL ;  Q6A5D0, UXAC_PROAC ;  Q98EW1, UXAC_RHILO ;
DR   Q92V04, UXAC_RHIME ;  B5F623, UXAC_SALA4 ;  A9MQL9, UXAC_SALAR ;
DR   Q57JX8, UXAC_SALCH ;  B5FV01, UXAC_SALDC ;  B5QYB2, UXAC_SALEP ;
DR   B5RE96, UXAC_SALG2 ;  B4THM8, UXAC_SALHS ;  B4T5P8, UXAC_SALNS ;
DR   Q5PMP8, UXAC_SALPA ;  A9N4U7, UXAC_SALPB ;  C0PYB6, UXAC_SALPC ;
DR   B5BFV0, UXAC_SALPK ;  B4TVB3, UXAC_SALSV ;  Q8Z3R7, UXAC_SALTI ;
DR   Q8ZM23, UXAC_SALTY ;  A8GJX5, UXAC_SERP5 ;  B2U1U1, UXAC_SHIB3 ;
DR   Q31WU2, UXAC_SHIBS ;  Q0T0H6, UXAC_SHIF8 ;  P0A8G5, UXAC_SHIFL ;
DR   Q3YXD9, UXAC_SHISS ;  Q01VN6, UXAC_SOLUE ;  Q1GNM2, UXAC_SPHAL ;
DR   A5V7I1, UXAC_SPHWW ;  Q4L320, UXAC_STAHJ ;  Q3K204, UXAC_STRA1 ;
DR   Q8E6A3, UXAC_STRA3 ;  Q8E0M9, UXAC_STRA5 ;  C0MA32, UXAC_STRE4 ;
DR   B4U237, UXAC_STREM ;  C1CAV7, UXAC_STRP7 ;  C0MCL4, UXAC_STRS7 ;
DR   B9DSL9, UXAC_STRU0 ;  Q9WXR9, UXAC_THEMA ;  B9K773, UXAC_THENN ;
DR   A5IL06, UXAC_THEP1 ;  B1LA87, UXAC_THESQ ;  Q8R8Q6, UXAC_THETN ;
DR   B1GZ68, UXAC_UNCTG ;  Q87FH3, UXAC_VIBPA ;  Q8D556, UXAC_VIBVU ;
DR   Q7MBZ3, UXAC_VIBVY ;  Q8PET9, UXAC_XANAC ;  Q3BMC5, UXAC_XANC5 ;
DR   Q4UNX6, UXAC_XANC8 ;  B0RZ13, UXAC_XANCB ;  Q8P3F4, UXAC_XANCP ;
DR   Q2NXQ2, UXAC_XANOM ;  Q9AM27, UXAC_XANOR ;  A1JR25, UXAC_YERE8 ;
DR   A7FE06, UXAC_YERP3 ;  Q1C300, UXAC_YERPA ;  B2K3C6, UXAC_YERPB ;
DR   Q8ZIC6, UXAC_YERPE ;  A9R1P0, UXAC_YERPG ;  Q1CMK0, UXAC_YERPN ;
DR   A4THL9, UXAC_YERPP ;  Q665N8, UXAC_YERPS ;  B1JL96, UXAC_YERPY ;
//
ID   5.3.1.13
DE   Arabinose-5-phosphate isomerase.
AN   Arabinose phosphate isomerase.
AN   Phosphoarabinoisomerase.
CA   D-arabinose 5-phosphate = D-ribulose 5-phosphate.
PR   PROSITE; PDOC51464;
DR   Q8X4S5, GUTQ_ECO57 ;  Q8FEN7, GUTQ_ECOL6 ;  P17115, GUTQ_ECOLI ;
DR   Q8Z4C7, GUTQ_SALTI ;  Q8ZMJ9, GUTQ_SALTY ;  Q83MK2, GUTQ_SHIFL ;
DR   Q8X9J0, KDSD_ECO57 ;  Q8FD73, KDSD_ECOL6 ;  P45395, KDSD_ECOLI ;
DR   Q8Z3G6, KDSD_SALTI ;  Q8ZLS1, KDSD_SALTY ;  Q83JF4, KDSD_SHIFL ;
DR   Q8D1Q8, KDSD_YERPE ;  P42502, KPSF1_ECOLX;  Q47334, KPSF5_ECOLX;
DR   Q8FDQ2, KPSF_ECOL6 ;  Q9M1T1, SETH3_ARATH;
//
ID   5.3.1.14
DE   L-rhamnose isomerase.
AN   Rhamnose isomerase.
CA   L-rhamnose = L-rhamnulose.
DR   Q5WL39, RHAAB_BACSK;  Q9KCL9, RHAA_BACHD ;  O05264, RHAA_BACSU ;
DR   Q8A1A2, RHAA_BACTN ;  A8AL30, RHAA_CITK8 ;  A6LQK4, RHAA_CLOB8 ;
DR   A7ZUB4, RHAA_ECO24 ;  B7UNM4, RHAA_ECO27 ;  B7MI35, RHAA_ECO45 ;
DR   B7L9F3, RHAA_ECO55 ;  P58506, RHAA_ECO57 ;  B5YZ40, RHAA_ECO5E ;
DR   B7NUA3, RHAA_ECO7I ;  B7MQZ3, RHAA_ECO81 ;  B7M6V5, RHAA_ECO8A ;
DR   C5A071, RHAA_ECOBW ;  B1XB70, RHAA_ECODH ;  A8A706, RHAA_ECOHS ;
DR   A1AI80, RHAA_ECOK1 ;  Q0TAG0, RHAA_ECOL5 ;  Q8FBE0, RHAA_ECOL6 ;
DR   B1IVH5, RHAA_ECOLC ;  P32170, RHAA_ECOLI ;  B7NFK1, RHAA_ECOLU ;
DR   B6I4P5, RHAA_ECOSE ;  B1LMU3, RHAA_ECOSM ;  A4WG93, RHAA_ENT38 ;
DR   Q838L2, RHAA_ENTFA ;  A7ML61, RHAA_ENTS8 ;  Q6DA24, RHAA_ERWCT ;
DR   B7LVE0, RHAA_ESCF3 ;  B5XZ52, RHAA_KLEP3 ;  A6TGA7, RHAA_KLEP7 ;
DR   Q88S51, RHAA_LACPL ;  Q926R1, RHAA_LISIN ;  C1L0I1, RHAA_LISMC ;
DR   Q71VR4, RHAA_LISMF ;  B8DCW2, RHAA_LISMH ;  Q8Y3I7, RHAA_LISMO ;
DR   Q65Q25, RHAA_MANSM ;  Q8ESX0, RHAA_OCEIH ;  C6DJR2, RHAA_PECCP ;
DR   Q7UYE5, RHAA_RHOBA ;  B5F0M7, RHAA_SALA4 ;  A9MI67, RHAA_SALAR ;
DR   Q57HH0, RHAA_SALCH ;  B5FPP3, RHAA_SALDC ;  B5QWY2, RHAA_SALEP ;
DR   B5RFC5, RHAA_SALG2 ;  B4TBY1, RHAA_SALHS ;  B4SZZ1, RHAA_SALNS ;
DR   Q5PKG4, RHAA_SALPA ;  A9MZC5, RHAA_SALPB ;  C0Q3L2, RHAA_SALPC ;
DR   B5BJG6, RHAA_SALPK ;  B4TPQ7, RHAA_SALSV ;  Q8Z2V3, RHAA_SALTI ;
DR   P27031, RHAA_SALTY ;  Q31U86, RHAA_SHIBS ;  Q0SZ93, RHAA_SHIF8 ;
DR   Q83IU4, RHAA_SHIFL ;  Q3YV73, RHAA_SHISS ;  C4LCV5, RHAA_TOLAT ;
DR   A7FN82, RHAA_YERP3 ;  Q1C0V8, RHAA_YERPA ;  B2K1W1, RHAA_YERPB ;
DR   P58507, RHAA_YERPE ;  A9QYS2, RHAA_YERPG ;  Q1CEB2, RHAA_YERPN ;
DR   A4TRT1, RHAA_YERPP ;  Q66FF4, RHAA_YERPS ;  B1JNC9, RHAA_YERPY ;
//
ID   5.3.1.15
DE   D-lyxose ketol-isomerase.
AN   D-lyxose isomerase.
CA   D-lyxose = D-xylulose.
DR   A3E7Z6, DLYKI_COHLA;
//
ID   5.3.1.16
DE   1-(5-phosphoribosyl)-5-
DE   ((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide
DE   isomerase.
AN   N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-
AN   imidazolecarboxamide isomerase.
AN   Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
CA   1-(5-phosphoribosyl)-5-
CA   ((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide =
CA   5-((5-phospho-1-deoxyribulos-1-ylamino)methylideneamino)-1-
CA   (5-phosphoribosyl)imidazole-4-carboxamide.
DR   Q7N6I4, HIS41_PHOLL;  Q5LU97, HIS41_SILPO;  Q1GHT0, HIS41_SILST;
DR   Q7N8D1, HIS42_PHOLL;  Q5LR59, HIS42_SILPO;  Q1GEZ5, HIS42_SILST;
DR   B0C904, HIS4_ACAM1 ;  A1TKZ3, HIS4_ACIAC ;  Q6F7A5, HIS4_ACIAD ;
DR   B7GVK1, HIS4_ACIB3 ;  B7IBD1, HIS4_ACIB5 ;  B2I0N7, HIS4_ACIBC ;
DR   B0VPB7, HIS4_ACIBS ;  A3M9N4, HIS4_ACIBT ;  B0V8R7, HIS4_ACIBY ;
DR   A0LTS5, HIS4_ACIC1 ;  A5FYE4, HIS4_ACICJ ;  B9MDV7, HIS4_ACIET ;
DR   B7JA18, HIS4_ACIF2 ;  B5EQF1, HIS4_ACIF5 ;  A1W434, HIS4_ACISJ ;
DR   A3N3W4, HIS4_ACTP2 ;  B3GZH2, HIS4_ACTP7 ;  B0BU54, HIS4_ACTPJ ;
DR   A6VQ73, HIS4_ACTSZ ;  A0KKB4, HIS4_AERHH ;  A4SMQ0, HIS4_AERS4 ;
DR   B9JG66, HIS4_AGRRK ;  P58790, HIS4_AGRT5 ;  B9JXW8, HIS4_AGRVS ;
DR   Q0VM71, HIS4_ALCBS ;  Q0A5D2, HIS4_ALHEH ;  B6EJ92, HIS4_ALISL ;
DR   A6TKT5, HIS4_ALKMQ ;  B4RU63, HIS4_ALTMD ;  B8JDL2, HIS4_ANAD2 ;
DR   Q2INW2, HIS4_ANADE ;  A7H8C3, HIS4_ANADF ;  B4UDJ9, HIS4_ANASK ;
DR   B9MJR4, HIS4_ANATD ;  Q3M7Q7, HIS4_ANAVT ;  O67328, HIS4_AQUAE ;
DR   O82782, HIS4_ARATH ;  A8ES24, HIS4_ARCB4 ;  O29276, HIS4_ARCFU ;
DR   Q5P794, HIS4_AROAE ;  A1R562, HIS4_ARTAT ;  A0JUZ7, HIS4_ARTS2 ;
DR   Q75AP1, HIS4_ASHGO ;  P26720, HIS4_AZOBR ;  A8HYT9, HIS4_AZOC5 ;
DR   B6YQ29, HIS4_AZOPC ;  A1KAV5, HIS4_AZOSB ;  C1DJD2, HIS4_AZOVD ;
DR   A7Z963, HIS4_BACA2 ;  C3P505, HIS4_BACAA ;  C3L9P8, HIS4_BACAC ;
DR   A0RBM1, HIS4_BACAH ;  Q81T59, HIS4_BACAN ;  B7JFZ4, HIS4_BACC0 ;
DR   P62352, HIS4_BACC1 ;  B7INA2, HIS4_BACC2 ;  C1EMQ6, HIS4_BACC3 ;
DR   B7HHG4, HIS4_BACC4 ;  B7HKD3, HIS4_BACC7 ;  A7GMU9, HIS4_BACCN ;
DR   B9IUZ9, HIS4_BACCQ ;  Q81G03, HIS4_BACCR ;  Q63DW9, HIS4_BACCZ ;
DR   Q5LBD6, HIS4_BACFN ;  Q64RT1, HIS4_BACFR ;  Q9K6Z5, HIS4_BACHD ;
DR   Q6HLE4, HIS4_BACHK ;  Q65EG2, HIS4_BACLD ;  A8FHR0, HIS4_BACP2 ;
DR   Q5WDI1, HIS4_BACSK ;  O35006, HIS4_BACSU ;  Q8A7Z5, HIS4_BACTN ;
DR   A6L6Z1, HIS4_BACV8 ;  A9VLH6, HIS4_BACWK ;  Q1LT71, HIS4_BAUCH ;
DR   B2ICL3, HIS4_BEII9 ;  B8DSW1, HIS4_BIFA0 ;  A1A2H2, HIS4_BIFAA ;
DR   B3DQA4, HIS4_BIFLD ;  Q8G4S5, HIS4_BIFLO ;  B7GQ51, HIS4_BIFLS ;
DR   Q7VQW6, HIS4_BLOFL ;  Q494D7, HIS4_BLOPB ;  Q2KTT2, HIS4_BORA1 ;
DR   Q7WDY0, HIS4_BORBR ;  Q7W2Y0, HIS4_BORPA ;  A9HWC3, HIS4_BORPD ;
DR   Q7VSY7, HIS4_BORPE ;  C0QWR6, HIS4_BRAHW ;  Q89WM5, HIS4_BRAJA ;
DR   A5E8E8, HIS4_BRASB ;  A4YJV4, HIS4_BRASO ;  C0Z6P5, HIS4_BREBN ;
DR   B2S983, HIS4_BRUA1 ;  Q2YQY9, HIS4_BRUA2 ;  Q57AH4, HIS4_BRUAB ;
DR   A9M9R8, HIS4_BRUC2 ;  C0RFX2, HIS4_BRUMB ;  Q8YE36, HIS4_BRUME ;
DR   A5VT42, HIS4_BRUO2 ;  B0CJI5, HIS4_BRUSI ;  Q8FY08, HIS4_BRUSU ;
DR   B8D8Q6, HIS4_BUCA5 ;  P57205, HIS4_BUCAI ;  Q9ZHE2, HIS4_BUCAP ;
DR   B8D710, HIS4_BUCAT ;  P59520, HIS4_BUCBP ;  Q058A3, HIS4_BUCCC ;
DR   B1YRW0, HIS4_BURA4 ;  Q1BS30, HIS4_BURCA ;  B1JUA4, HIS4_BURCC ;
DR   A0K3V7, HIS4_BURCH ;  B4E640, HIS4_BURCJ ;  Q0BIW5, HIS4_BURCM ;
DR   Q845U8, HIS4_BURM1 ;  A3MPU5, HIS4_BURM7 ;  A2S753, HIS4_BURM9 ;
DR   Q62GE4, HIS4_BURMA ;  A1V8H4, HIS4_BURMS ;  A3P028, HIS4_BURP0 ;
DR   Q3JN01, HIS4_BURP1 ;  A3NE94, HIS4_BURP6 ;  B2JHY0, HIS4_BURP8 ;
DR   B2SZ60, HIS4_BURPP ;  Q63Q91, HIS4_BURPS ;  Q39K86, HIS4_BURS3 ;
DR   Q2SUA7, HIS4_BURTA ;  A4JAW8, HIS4_BURVG ;  Q13TQ9, HIS4_BURXL ;
DR   A4XL21, HIS4_CALS8 ;  A7ZES8, HIS4_CAMC1 ;  A7GWX9, HIS4_CAMC5 ;
DR   A0RQL2, HIS4_CAMFF ;  A7I1W6, HIS4_CAMHC ;  A8FNR3, HIS4_CAMJ8 ;
DR   A7H5V3, HIS4_CAMJD ;  Q9PM74, HIS4_CAMJE ;  A1W1K3, HIS4_CAMJJ ;
DR   Q5HSJ0, HIS4_CAMJR ;  Q9HFV5, HIS4_CANAL ;  Q6FPN5, HIS4_CANGA ;
DR   Q3AD49, HIS4_CARHZ ;  Q9A230, HIS4_CAUCR ;  B0T799, HIS4_CAUSK ;
DR   B3PGA3, HIS4_CELJU ;  A0RZ77, HIS4_CENSY ;  A9WD26, HIS4_CHLAA ;
DR   B8G9S2, HIS4_CHLAD ;  Q3AT62, HIS4_CHLCH ;  B3QLK3, HIS4_CHLP8 ;
DR   B3EM61, HIS4_CHLPB ;  A1BDS2, HIS4_CHLPD ;  B9LI75, HIS4_CHLSY ;
DR   B3QRR1, HIS4_CHLT3 ;  Q8KF55, HIS4_CHLTE ;  Q1R079, HIS4_CHRSD ;
DR   Q7P0F0, HIS4_CHRVO ;  A8AEK0, HIS4_CITK8 ;  Q97KH9, HIS4_CLOAB ;
DR   A7FU80, HIS4_CLOB1 ;  C3KVX4, HIS4_CLOB6 ;  A6LT21, HIS4_CLOB8 ;
DR   B2UX21, HIS4_CLOBA ;  A5I244, HIS4_CLOBH ;  C1FN40, HIS4_CLOBJ ;
DR   B1ILA8, HIS4_CLOBK ;  A7GDQ5, HIS4_CLOBL ;  B8I5V5, HIS4_CLOCE ;
DR   Q18C71, HIS4_CLOD6 ;  B9E171, HIS4_CLOK1 ;  A5N7R0, HIS4_CLOK5 ;
DR   A0PXP7, HIS4_CLONN ;  A9KNX3, HIS4_CLOPH ;  A3DJF6, HIS4_CLOTH ;
DR   Q47XB4, HIS4_COLP3 ;  P60580, HIS4_CORDI ;  Q8FNZ7, HIS4_COREF ;
DR   O68602, HIS4_CORGL ;  Q4JW54, HIS4_CORJK ;  Q0K692, HIS4_CUPNH ;
DR   Q46WL7, HIS4_CUPPJ ;  B3R795, HIS4_CUPTR ;  B1WRP7, HIS4_CYAA5 ;
DR   B8HY50, HIS4_CYAP4 ;  B7KEI6, HIS4_CYAP7 ;  B7K3A9, HIS4_CYAP8 ;
DR   Q11VM2, HIS4_CYTH3 ;  Q6BUV9, HIS4_DEBHA ;  Q47AM2, HIS4_DECAR ;
DR   Q3Z6V7, HIS4_DEHE1 ;  Q3ZYM9, HIS4_DEHSC ;  Q1IWD2, HIS4_DEIGD ;
DR   Q9RRJ5, HIS4_DEIRA ;  A9BX71, HIS4_DELAS ;  B8FBL5, HIS4_DESAA ;
DR   C6BSE3, HIS4_DESAD ;  B1I557, HIS4_DESAP ;  B8J249, HIS4_DESDA ;
DR   Q311Y2, HIS4_DESDG ;  B8FP23, HIS4_DESHD ;  Q24QJ4, HIS4_DESHY ;
DR   C4XSN4, HIS4_DESMR ;  A8ZUC6, HIS4_DESOH ;  A4J708, HIS4_DESRM ;
DR   P62353, HIS4_DESVH ;  B8DNB4, HIS4_DESVM ;  A1VEV5, HIS4_DESVV ;
DR   B5YE89, HIS4_DICT6 ;  B8E2C7, HIS4_DICTD ;  A8LHX7, HIS4_DINSH ;
DR   A7ZNJ6, HIS4_ECO24 ;  B7UT61, HIS4_ECO27 ;  B7MDH8, HIS4_ECO45 ;
DR   B7L9Q1, HIS4_ECO55 ;  Q9S5G4, HIS4_ECO57 ;  B5YU80, HIS4_ECO5E ;
DR   B7NQG6, HIS4_ECO7I ;  B7MWU2, HIS4_ECO81 ;  B7M403, HIS4_ECO8A ;
DR   C4ZSB3, HIS4_ECOBW ;  B1X6W1, HIS4_ECODH ;  A8A1P8, HIS4_ECOHS ;
DR   A1ACN6, HIS4_ECOK1 ;  Q0TG63, HIS4_ECOL5 ;  Q8FG49, HIS4_ECOL6 ;
DR   B1IZ50, HIS4_ECOLC ;  P10371, HIS4_ECOLI ;  B7NC64, HIS4_ECOLU ;
DR   B6I851, HIS4_ECOSE ;  B1LP17, HIS4_ECOSM ;  Q1RA49, HIS4_ECOUT ;
DR   C5BG15, HIS4_EDWI9 ;  B2KCM6, HIS4_ELUMP ;  A4WC73, HIS4_ENT38 ;
DR   A7MHE2, HIS4_ENTS8 ;  Q6D407, HIS4_ERWCT ;  B2VFL2, HIS4_ERWT9 ;
DR   Q2N8I7, HIS4_ERYLH ;  B7LUF5, HIS4_ESCF3 ;  A5FFX7, HIS4_FLAJ1 ;
DR   A6GY76, HIS4_FLAPJ ;  Q0RFX1, HIS4_FRAAA ;  B0TY42, HIS4_FRAP2 ;
DR   Q2J8L2, HIS4_FRASC ;  A8LGR0, HIS4_FRASN ;  C1A4L9, HIS4_GEMAT ;
DR   B5EDR5, HIS4_GEOBB ;  Q5KVC9, HIS4_GEOKA ;  B3E618, HIS4_GEOLS ;
DR   Q39YP3, HIS4_GEOMG ;  B9M0L9, HIS4_GEOSF ;  P60581, HIS4_GEOSL ;
DR   C6E7F5, HIS4_GEOSM ;  A4ISR3, HIS4_GEOTN ;  A5G8T0, HIS4_GEOUR ;
DR   Q7NMQ9, HIS4_GLOVI ;  Q0BPX3, HIS4_GRABC ;  A0M284, HIS4_GRAFK ;
DR   Q4QN70, HIS4_HAEI8 ;  A5UA16, HIS4_HAEIE ;  A5UGY5, HIS4_HAEIG ;
DR   P44435, HIS4_HAEIN ;  Q2SMB3, HIS4_HAHCH ;  A1WW06, HIS4_HALHL ;
DR   Q5UZH1, HIS4_HALMA ;  B8D115, HIS4_HALOH ;  Q9HN14, HIS4_HALSA ;
DR   Q18DL2, HIS4_HALWD ;  Q7VHY5, HIS4_HELHP ;  B0TDM8, HIS4_HELMI ;
DR   A9B5I3, HIS4_HERA2 ;  A4G9I7, HIS4_HERAR ;  Q0C639, HIS4_HYPNA ;
DR   Q5QWQ6, HIS4_IDILO ;  A6T377, HIS4_JANMA ;  Q28NK3, HIS4_JANSC ;
DR   B5XPE3, HIS4_KLEP3 ;  A6TBC7, HIS4_KLEP7 ;  Q6CQL7, HIS4_KLULA ;
DR   Q039B4, HIS4_LACC3 ;  B3WED2, HIS4_LACCB ;  Q02131, HIS4_LACLA ;
DR   A2RKR8, HIS4_LACLM ;  Q02YX0, HIS4_LACLS ;  Q88UE2, HIS4_LACPL ;
DR   Q5X5X3, HIS4_LEGPA ;  A5IB92, HIS4_LEGPC ;  Q5ZW91, HIS4_LEGPH ;
DR   Q5WX95, HIS4_LEGPL ;  Q6AE15, HIS4_LEIXX ;  B0SDS6, HIS4_LEPBA ;
DR   Q04W72, HIS4_LEPBJ ;  Q056S8, HIS4_LEPBL ;  B0SLU9, HIS4_LEPBP ;
DR   B1XX77, HIS4_LEPCP ;  P62354, HIS4_LEPIC ;  Q8F9R5, HIS4_LEPIN ;
DR   Q03VX9, HIS4_LEUMM ;  Q92E87, HIS4_LISIN ;  C1L0J3, HIS4_LISMC ;
DR   Q722Y6, HIS4_LISMF ;  B8DA61, HIS4_LISMH ;  Q8Y9G4, HIS4_LISMO ;
DR   A0AG16, HIS4_LISW6 ;  Q2VYI9, HIS4_MAGSA ;  A0LCF2, HIS4_MAGSM ;
DR   Q65RC0, HIS4_MANSM ;  A1U5H6, HIS4_MARAV ;  Q0AP83, HIS4_MARMM ;
DR   Q11CK8, HIS4_MESSB ;  A6UWA5, HIS4_META3 ;  Q8TU55, HIS4_METAC ;
DR   A7I773, HIS4_METB6 ;  Q46CW8, HIS4_METBF ;  Q12WC6, HIS4_METBU ;
DR   Q603K2, HIS4_METCA ;  Q1H4R3, HIS4_METFK ;  Q2FN18, HIS4_METHJ ;
DR   Q58927, HIS4_METJA ;  Q8TYD6, HIS4_METKA ;  A2SQR0, HIS4_METLZ ;
DR   A4FZ85, HIS4_METM5 ;  A9A6L5, HIS4_METM6 ;  A6VJ52, HIS4_METM7 ;
DR   Q8PWS2, HIS4_METMA ;  A3CTR9, HIS4_METMJ ;  P62357, HIS4_METMP ;
DR   B8IPH4, HIS4_METNO ;  B8GJY2, HIS4_METPE ;  A2SE08, HIS4_METPP ;
DR   B0UHR6, HIS4_METS4 ;  B8EM86, HIS4_METSB ;  Q2NHB3, HIS4_METST ;
DR   O26931, HIS4_METTH ;  Q50757, HIS4_METTL ;  A0B7W4, HIS4_METTP ;
DR   P05324, HIS4_METVA ;  P05325, HIS4_METVO ;  A6US29, HIS4_METVS ;
DR   B0JGL3, HIS4_MICAN ;  Q2RGW1, HIS4_MOOTA ;  A0QHH8, HIS4_MYCA1 ;
DR   B1MBX5, HIS4_MYCA9 ;  P60579, HIS4_MYCBO ;  A1KJ19, HIS4_MYCBP ;
DR   C1ANM5, HIS4_MYCBT ;  Q9CC56, HIS4_MYCLE ;  P60583, HIS4_MYCPA ;
DR   A3Q127, HIS4_MYCSJ ;  A1UHK4, HIS4_MYCSK ;  Q1B7G8, HIS4_MYCSS ;
DR   A5U2V9, HIS4_MYCTA ;  P60578, HIS4_MYCTU ;  A0PP18, HIS4_MYCUA ;
DR   A1T8W5, HIS4_MYCVP ;  Q1D4M2, HIS4_MYXXD ;  Q3IT10, HIS4_NATPD ;
DR   B9L7G2, HIS4_NAUPA ;  Q5FA22, HIS4_NEIG1 ;  B4RJN4, HIS4_NEIG2 ;
DR   A9M2Q6, HIS4_NEIM0 ;  Q9JVH4, HIS4_NEIMA ;  Q9K0H3, HIS4_NEIMB ;
DR   A1KSN7, HIS4_NEIMF ;  Q7RXQ8, HIS4_NEUCR ;  Q0AEU2, HIS4_NITEC ;
DR   Q82WM5, HIS4_NITEU ;  Q1QRX1, HIS4_NITHX ;  A9A5X1, HIS4_NITMS ;
DR   Q2YAU9, HIS4_NITMU ;  Q3J6Q2, HIS4_NITOC ;  A6Q4V9, HIS4_NITSB ;
DR   Q3SWF0, HIS4_NITWN ;  Q5YYP5, HIS4_NOCFA ;  A1SL57, HIS4_NOCSJ ;
DR   B2J2G1, HIS4_NOSP7 ;  Q8YNQ6, HIS4_NOSS1 ;  Q2G9L9, HIS4_NOVAD ;
DR   Q8ESS1, HIS4_OCEIH ;  A6WX53, HIS4_OCHA4 ;  B6JCG4, HIS4_OLICO ;
DR   B1ZW12, HIS4_OPITP ;  A6LDI6, HIS4_PARD8 ;  A1B387, HIS4_PARDP ;
DR   A7HSH1, HIS4_PARL1 ;  Q9CLM1, HIS4_PASMU ;  C6DF72, HIS4_PECCP ;
DR   Q3A136, HIS4_PELCD ;  Q3B287, HIS4_PELLD ;  B4SCY8, HIS4_PELPB ;
DR   A1ATI1, HIS4_PELPD ;  A5CZ74, HIS4_PELTS ;  Q4FNT6, HIS4_PELUB ;
DR   C0QRW6, HIS4_PERMH ;  P62355, HIS4_PHOPR ;  A1VK41, HIS4_POLNA ;
DR   B1XSV2, HIS4_POLNS ;  Q12FC8, HIS4_POLSJ ;  A4SV19, HIS4_POLSQ ;
DR   B4S4Z8, HIS4_PROA2 ;  Q6A8L1, HIS4_PROAC ;  A3PCK5, HIS4_PROM0 ;
DR   A2C1N4, HIS4_PROM1 ;  A2CAH8, HIS4_PROM3 ;  A9BAN4, HIS4_PROM4 ;
DR   A2BW33, HIS4_PROM5 ;  Q31B81, HIS4_PROM9 ;  Q7VC70, HIS4_PROMA ;
DR   B4ESZ9, HIS4_PROMH ;  Q7TV18, HIS4_PROMM ;  Q7TUA7, HIS4_PROMP ;
DR   A2BQT3, HIS4_PROMS ;  Q46LD2, HIS4_PROMT ;  A4SG77, HIS4_PROVI ;
DR   Q48C80, HIS4_PSE14 ;  Q15RU5, HIS4_PSEA6 ;  A6VDR0, HIS4_PSEA7 ;
DR   B7V3N4, HIS4_PSEA8 ;  Q02EM5, HIS4_PSEAB ;  Q9HU43, HIS4_PSEAE ;
DR   Q1I3G7, HIS4_PSEE4 ;  Q4KJS5, HIS4_PSEF5 ;  C3K6V2, HIS4_PSEFS ;
DR   Q3ICF4, HIS4_PSEHT ;  A4Y084, HIS4_PSEMY ;  A5VX75, HIS4_PSEP1 ;
DR   Q3KJI6, HIS4_PSEPF ;  B0KI44, HIS4_PSEPG ;  Q88R42, HIS4_PSEPK ;
DR   B1JED2, HIS4_PSEPW ;  Q87UG3, HIS4_PSESM ;  Q4ZLQ1, HIS4_PSEU2 ;
DR   A4VRW0, HIS4_PSEU5 ;  Q4FPV8, HIS4_PSYA2 ;  Q1Q803, HIS4_PSYCK ;
DR   A1SVD0, HIS4_PSYIN ;  Q8ZY14, HIS4_PYRAE ;  P58791, HIS4_PYRFU ;
DR   Q5JFU9, HIS4_PYRKO ;  Q1LIB1, HIS4_RALME ;  B2UEE6, HIS4_RALPJ ;
DR   Q8XV84, HIS4_RALSO ;  A9WQA3, HIS4_RENSM ;  B3PWI0, HIS4_RHIE6 ;
DR   Q2KE60, HIS4_RHIEC ;  Q1MNC1, HIS4_RHIL3 ;  Q98CT3, HIS4_RHILO ;
DR   B5ZV92, HIS4_RHILW ;  Q92TB2, HIS4_RHIME ;  C3MBC2, HIS4_RHISN ;
DR   Q7UG70, HIS4_RHOBA ;  O30725, HIS4_RHOCB ;  B6IWI6, HIS4_RHOCS ;
DR   C1A0L8, HIS4_RHOE4 ;  Q21U92, HIS4_RHOFD ;  C1ATY9, HIS4_RHOOB ;
DR   Q2J341, HIS4_RHOP2 ;  Q07UQ8, HIS4_RHOP5 ;  P60582, HIS4_RHOPA ;
DR   Q21CK4, HIS4_RHOPB ;  Q13E39, HIS4_RHOPS ;  B3Q950, HIS4_RHOPT ;
DR   Q2RNA6, HIS4_RHORT ;  A3PI63, HIS4_RHOS1 ;  P50936, HIS4_RHOS4 ;
DR   A4WUS7, HIS4_RHOS5 ;  B9KPC9, HIS4_RHOSK ;  Q0SHY5, HIS4_RHOSR ;
DR   A7NN50, HIS4_ROSCS ;  Q162Q2, HIS4_ROSDO ;  A5UY50, HIS4_ROSS1 ;
DR   Q1AX07, HIS4_RUBXD ;  A1AXM7, HIS4_RUTMC ;  Q21NH6, HIS4_SACD2 ;
DR   A4FLL9, HIS4_SACEN ;  B5EX43, HIS4_SALA4 ;  A8LX58, HIS4_SALAI ;
DR   A9ML12, HIS4_SALAR ;  Q57MR9, HIS4_SALCH ;  B5FM45, HIS4_SALDC ;
DR   B5QZL6, HIS4_SALEP ;  B5RBR6, HIS4_SALG2 ;  B4T9N8, HIS4_SALHS ;
DR   B4SX45, HIS4_SALNS ;  Q5PDP7, HIS4_SALPA ;  A9N7S1, HIS4_SALPB ;
DR   C0Q1J8, HIS4_SALPC ;  B5BFB6, HIS4_SALPK ;  Q2S296, HIS4_SALRD ;
DR   B4TMR9, HIS4_SALSV ;  Q8Z5J7, HIS4_SALTI ;  A4X9Q0, HIS4_SALTO ;
DR   P10372, HIS4_SALTY ;  Q10184, HIS4_SCHPO ;  A8GC75, HIS4_SERP5 ;
DR   A1S6Z5, HIS4_SHEAM ;  B8E9A0, HIS4_SHEB2 ;  A3D5B0, HIS4_SHEB5 ;
DR   A6WP21, HIS4_SHEB8 ;  A9L4B9, HIS4_SHEB9 ;  Q12NS9, HIS4_SHEDO ;
DR   Q083K0, HIS4_SHEFN ;  B0TQY9, HIS4_SHEHH ;  A3QF20, HIS4_SHELP ;
DR   Q8EFB5, HIS4_SHEON ;  A8H5E4, HIS4_SHEPA ;  A4Y7H1, HIS4_SHEPC ;
DR   B8CR53, HIS4_SHEPW ;  A0KWB1, HIS4_SHESA ;  A8FWD0, HIS4_SHESH ;
DR   Q0HJ98, HIS4_SHESM ;  Q0HUN5, HIS4_SHESR ;  A1RJ17, HIS4_SHESW ;
DR   B1KRG4, HIS4_SHEWM ;  B2TYF6, HIS4_SHIB3 ;  Q323I8, HIS4_SHIBS ;
DR   Q32EF3, HIS4_SHIDS ;  Q0T3A3, HIS4_SHIF8 ;  Q83R04, HIS4_SHIFL ;
DR   Q3Z0G1, HIS4_SHISS ;  A6UEK4, HIS4_SINMW ;  Q2NTX5, HIS4_SODGM ;
DR   A9GB86, HIS4_SORC5 ;  Q1GNC2, HIS4_SPHAL ;  A5V9V9, HIS4_SPHWW ;
DR   A7X764, HIS4_STAA1 ;  A6U559, HIS4_STAA2 ;  Q2FDI7, HIS4_STAA3 ;
DR   Q2FUU2, HIS4_STAA8 ;  A5IWA1, HIS4_STAA9 ;  Q2YZ70, HIS4_STAAB ;
DR   Q5HCM3, HIS4_STAAC ;  A6QKG2, HIS4_STAAE ;  P64359, HIS4_STAAM ;
DR   P64360, HIS4_STAAN ;  Q6GDD0, HIS4_STAAR ;  Q6G601, HIS4_STAAS ;
DR   A8Z5H4, HIS4_STAAT ;  Q8NUI2, HIS4_STAAW ;  B9DIP2, HIS4_STACT ;
DR   Q5HKP1, HIS4_STAEQ ;  Q8CQ93, HIS4_STAES ;  Q4A048, HIS4_STAS1 ;
DR   Q82AA1, HIS4_STRAW ;  P16250, HIS4_STRCO ;  B1W0M4, HIS4_STRGG ;
DR   B4STP1, HIS4_STRM5 ;  B2FPM3, HIS4_STRMK ;  Q8DTR2, HIS4_STRMU ;
DR   A3CNT1, HIS4_STRSV ;  Q03K81, HIS4_STRTD ;  Q30PY1, HIS4_SULDN ;
DR   A6QBN6, HIS4_SULNB ;  O33772, HIS4_SULSO ;  B2V6T1, HIS4_SULSY ;
DR   Q970Z2, HIS4_SULTO ;  Q67KH9, HIS4_SYMTH ;  Q2LVE9, HIS4_SYNAS ;
DR   Q8GJM0, HIS4_SYNE7 ;  A0LHK5, HIS4_SYNFM ;  Q2JRV8, HIS4_SYNJA ;
DR   Q2JK82, HIS4_SYNJB ;  B1XQI2, HIS4_SYNP2 ;  Q5MZR5, HIS4_SYNP6 ;
DR   A5GKX4, HIS4_SYNPW ;  Q7U851, HIS4_SYNPX ;  A5GSQ4, HIS4_SYNR3 ;
DR   Q0I9E5, HIS4_SYNS3 ;  Q3AYT2, HIS4_SYNS9 ;  Q3AIG3, HIS4_SYNSC ;
DR   Q0AW40, HIS4_SYNWW ;  P74561, HIS4_SYNY3 ;  C5BMF4, HIS4_TERTT ;
DR   Q8DMA5, HIS4_THEEB ;  Q47QS4, HIS4_THEFY ;  Q9X0C7, HIS4_THEMA ;
DR   B9K9S2, HIS4_THENN ;  B6YWA8, HIS4_THEON ;  A5INE5, HIS4_THEP1 ;
DR   Q9RPQ5, HIS4_THEP3 ;  B0K628, HIS4_THEPX ;  B9KXJ4, HIS4_THERP ;
DR   B1L872, HIS4_THESQ ;  P62356, HIS4_THET2 ;  Q5SJ49, HIS4_THET8 ;
DR   Q8R884, HIS4_THETN ;  B5YIB4, HIS4_THEYD ;  Q31E65, HIS4_THICR ;
DR   Q3SEU7, HIS4_THIDA ;  B8GU31, HIS4_THISH ;  C4LFI3, HIS4_TOLAT ;
DR   Q10Y87, HIS4_TRIEI ;  Q0W0J3, HIS4_UNCMA ;  B1H0E7, HIS4_UNCTG ;
DR   C5CQJ5, HIS4_VARPS ;  A1WR23, HIS4_VEREI ;  A5CVQ5, HIS4_VESOH ;
DR   Q9KSW9, HIS4_VIBCH ;  Q5E634, HIS4_VIBF1 ;  B5FDA3, HIS4_VIBFM ;
DR   A7MX07, HIS4_VIBHB ;  Q87QK7, HIS4_VIBPA ;  Q8D8Q4, HIS4_VIBVU ;
DR   Q7MLS2, HIS4_VIBVY ;  Q7M9W9, HIS4_WOLSU ;  Q8PLG7, HIS4_XANAC ;
DR   Q3BUF3, HIS4_XANC5 ;  Q4UU44, HIS4_XANC8 ;  B0RSL8, HIS4_XANCB ;
DR   Q8P9P0, HIS4_XANCP ;  Q2P3J9, HIS4_XANOM ;  B2SKN4, HIS4_XANOP ;
DR   Q5H0K7, HIS4_XANOR ;  A7IHP0, HIS4_XANP2 ;  B2I5X7, HIS4_XYLF2 ;
DR   Q9PBC9, HIS4_XYLFA ;  B0U3A9, HIS4_XYLFM ;  Q87C33, HIS4_XYLFT ;
DR   Q6C2U0, HIS4_YARLI ;  P40545, HIS4_YEAST ;  A1JTW2, HIS4_YERE8 ;
DR   A7FJH4, HIS4_YERP3 ;  Q1C9R5, HIS4_YERPA ;  B2JZM5, HIS4_YERPB ;
DR   Q8ZFX9, HIS4_YERPE ;  A9R2K8, HIS4_YERPG ;  Q1CGW6, HIS4_YERPN ;
DR   A4TKK7, HIS4_YERPP ;  Q66C53, HIS4_YERPS ;  B1JPW4, HIS4_YERPY ;
DR   Q5NMD5, HIS4_ZYMMO ;
//
ID   5.3.1.17
DE   4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase.
AN   5-keto-4-deoxyuronate isomerase.
CA   4-deoxy-L-threo-5-hexosulose uronate = 3-deoxy-D-glycero-2,5-
CA   hexodiulosonate.
DR   Q8A2S4, KDUI1_BACTN;  Q838L9, KDUI1_ENTFA;  Q930T2, KDUI1_RHIME;
DR   Q8A0B5, KDUI2_BACTN;  Q832G5, KDUI2_ENTFA;  Q92V09, KDUI2_RHIME;
DR   Q8UB75, KDUI_AGRT5 ;  B9MNC2, KDUI_ANATD ;  Q5LJ16, KDUI_BACFN ;
DR   Q650K4, KDUI_BACFR ;  Q9KAX0, KDUI_BACHD ;  Q65E69, KDUI_BACLD ;
DR   A8FI32, KDUI_BACP2 ;  Q5WJC2, KDUI_BACSK ;  P50843, KDUI_BACSU ;
DR   B4EH54, KDUI_BURCJ ;  B2T4U5, KDUI_BURPP ;  B8H5V5, KDUI_CAUCN ;
DR   Q9A873, KDUI_CAUCR ;  A9KNI2, KDUI_CLOPH ;  Q05529, KDUI_DICD3 ;
DR   A7ZQV1, KDUI_ECO24 ;  B7UHR2, KDUI_ECO27 ;  B7MM49, KDUI_ECO45 ;
DR   B7LF20, KDUI_ECO55 ;  Q8X6I8, KDUI_ECO57 ;  B5Z4G1, KDUI_ECO5E ;
DR   B7NVY9, KDUI_ECO7I ;  B7MZE3, KDUI_ECO81 ;  B7LY99, KDUI_ECO8A ;
DR   C5A0C6, KDUI_ECOBW ;  B1XED7, KDUI_ECODH ;  A8A3X7, KDUI_ECOHS ;
DR   Q0TDY9, KDUI_ECOL5 ;  Q8FE97, KDUI_ECOL6 ;  B1IU01, KDUI_ECOLC ;
DR   Q46938, KDUI_ECOLI ;  B7N775, KDUI_ECOLU ;  B6I6W8, KDUI_ECOSE ;
DR   B1LR41, KDUI_ECOSM ;  Q1R7G9, KDUI_ECOUT ;  C5BFL5, KDUI_EDWI9 ;
DR   A4WE30, KDUI_ENT38 ;  A7MPJ5, KDUI_ENTS8 ;  C4Z0J8, KDUI_EUBE2 ;
DR   A6W4E9, KDUI_KINRD ;  Q03U25, KDUI_LACBA ;  Q034I2, KDUI_LACC3 ;
DR   B3WB42, KDUI_LACCB ;  Q8EMM9, KDUI_OCEIH ;  B1ZP50, KDUI_OPITP ;
DR   Q9XB53, KDUI_PECCC ;  B4RGF4, KDUI_PHEZH ;  A3PLM1, KDUI_RHOS1 ;
DR   Q3J0N0, KDUI_RHOS4 ;  A4WV81, KDUI_RHOS5 ;  B9KKM8, KDUI_RHOSK ;
DR   B5F4W4, KDUI_SALA4 ;  Q57K99, KDUI_SALCH ;  B5FUC8, KDUI_SALDC ;
DR   B5QWV0, KDUI_SALEP ;  B5RDZ4, KDUI_SALG2 ;  B4TGS4, KDUI_SALHS ;
DR   B4T512, KDUI_SALNS ;  Q5PEP3, KDUI_SALPA ;  A9N3I7, KDUI_SALPB ;
DR   C0PXK7, KDUI_SALPC ;  B5BFI4, KDUI_SALPK ;  B4TUN8, KDUI_SALSV ;
DR   Q8Z3Z9, KDUI_SALTI ;  Q8ZM98, KDUI_SALTY ;  B2TYP7, KDUI_SHIB3 ;
DR   Q31XE5, KDUI_SHIBS ;  Q0T121, KDUI_SHIF8 ;  Q83QB2, KDUI_SHIFL ;
DR   Q3YY15, KDUI_SHISS ;  C4LDM6, KDUI_TOLAT ;  Q8PR01, KDUI_XANAC ;
DR   Q3BZD0, KDUI_XANC5 ;  Q4V0C6, KDUI_XANC8 ;  B0RLD0, KDUI_XANCB ;
DR   Q8PE32, KDUI_XANCP ;  A1JMF5, KDUI_YERE8 ;  A7FHE3, KDUI_YERP3 ;
DR   Q1C713, KDUI_YERPA ;  B2K682, KDUI_YERPB ;  Q8ZFH8, KDUI_YERPE ;
DR   A9R0C4, KDUI_YERPG ;  Q1CIE6, KDUI_YERPN ;  A4TLE6, KDUI_YERPP ;
DR   Q669X6, KDUI_YERPS ;  B1JJ01, KDUI_YERPY ;
//
ID   5.3.1.18
DE   Deleted entry.
//
ID   5.3.1.19
DE   Transferred entry: 2.6.1.16.
//
ID   5.3.1.20
DE   Ribose isomerase.
AN   D-ribose isomerase.
CA   D-ribose = D-ribulose.
CC   -!- Also acts on L-lyxose and L-rhamnose.
//
ID   5.3.1.21
DE   Corticosteroid side-chain-isomerase.
CA   11-deoxycorticosterone = 20-hydroxy-3-oxopregn-4-en-21-al.
CC   -!- An epimerization at C-20 and C-21 is probably catalyzed by the same
CC       enzyme.
//
ID   5.3.1.22
DE   Hydroxypyruvate isomerase.
CA   Hydroxypyruvate = 2-hydroxy-3-oxopropanoate.
DR   Q11185, HYI_CAEEL  ;  Q7T3H9, HYI_DANRE  ;  P36951, HYI_DROME  ;
DR   P30147, HYI_ECOLI  ;  Q5T013, HYI_HUMAN  ;  Q8R1F5, HYI_MOUSE  ;
DR   Q6NUD4, HYI_XENLA  ;
//
ID   5.3.1.23
DE   S-methyl-5-thioribose-1-phosphate isomerase.
AN   1-phospho-5'-S-methylthioribose isomerase.
AN   1-PMTR isomerase.
AN   5-methylthio-5-deoxy-D-ribose-1-phosphate ketol-isomerase.
AN   5-methylthioribose-1-phosphate isomerase.
AN   Methylthioribose 1-phosphate isomerase.
AN   MTR-1-P isomerase.
AN   S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate aldose-ketose-isomerase.
AN   S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate ketol-isomerase.
AN   S-methyl-5-thio-D-ribose-1-phosphate aldose-ketose-isomerase.
CA   S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose
CA   1-phosphate.
DR   A0R946, MTNA1_BACAH;  Q81ZC2, MTNA1_BACAN;  Q81IK7, MTNA1_BACCR;
DR   Q63GN3, MTNA1_BACCZ;  Q6HP54, MTNA1_BACHK;  A9VRK3, MTNA1_BACWK;
DR   A9BJF6, MTNA1_PETMO;  A8F3A3, MTNA1_THELT;  Q4CY36, MTNA1_TRYCR;
DR   A0RI38, MTNA2_BACAH;  Q81MJ6, MTNA2_BACAN;  Q819F2, MTNA2_BACCR;
DR   Q635P7, MTNA2_BACCZ;  Q6HED3, MTNA2_BACHK;  A9VFD5, MTNA2_BACWK;
DR   A9BHC5, MTNA2_PETMO;  A8F7V1, MTNA2_THELT;  Q4D6B2, MTNA2_TRYCR;
DR   Q5YQZ6, MTNAB_NOCFA;  B0C8J2, MTNA_ACAM1 ;  Q1ISH2, MTNA_ACIBL ;
DR   A5FUV7, MTNA_ACICJ ;  Q16I17, MTNA_AEDAE ;  Q9YE84, MTNA_AERPE ;
DR   C0P108, MTNA_AJECG ;  A6R364, MTNA_AJECN ;  C5GGE5, MTNA_AJEDR ;
DR   C5JGS0, MTNA_AJEDS ;  Q0VPK6, MTNA_ALCBS ;  Q0AA70, MTNA_ALHEH ;
DR   Q2IH96, MTNA_ANADE ;  A7HIG6, MTNA_ANADF ;  B4UIU8, MTNA_ANASK ;
DR   Q3M785, MTNA_ANAVT ;  Q7PKS9, MTNA_ANOGA ;  O67879, MTNA_AQUAE ;
DR   Q9ZUG4, MTNA_ARATH ;  O29877, MTNA_ARCFU ;  C5FY68, MTNA_ARTOC ;
DR   Q75EI1, MTNA_ASHGO ;  A1CGN9, MTNA_ASPCL ;  B0Y5C3, MTNA_ASPFC ;
DR   Q4WNI1, MTNA_ASPFU ;  Q2UIM3, MTNA_ASPOR ;  Q0CFY3, MTNA_ASPTN ;
DR   C1DRQ7, MTNA_AZOVD ;  A7Z3X0, MTNA_BACA2 ;  Q731R7, MTNA_BACC1 ;
DR   A7GS56, MTNA_BACCN ;  Q65KK2, MTNA_BACLD ;  A8FCG5, MTNA_BACP2 ;
DR   O31662, MTNA_BACSU ;  Q0ZB81, MTNA_BOMMO ;  A6RHT9, MTNA_BOTFB ;
DR   Q2NL31, MTNA_BOVIN ;  A8XDI8, MTNA_CAEBR ;  Q93169, MTNA_CAEEL ;
DR   A4XKS3, MTNA_CALS8 ;  Q5AD59, MTNA_CANAL ;  C4YJ78, MTNA_CANAW ;
DR   B9WAG5, MTNA_CANDC ;  Q6FVY2, MTNA_CANGA ;  C5M614, MTNA_CANTT ;
DR   Q3ABU6, MTNA_CARHZ ;  Q2GM68, MTNA_CHAGB ;  A9WGQ8, MTNA_CHLAA ;
DR   B9LBK4, MTNA_CHLSY ;  Q8KBH1, MTNA_CHLTE ;  A8ANI3, MTNA_CITK8 ;
DR   C4YC37, MTNA_CLAL4 ;  A7FTE6, MTNA_CLOB1 ;  C3KTV5, MTNA_CLOB6 ;
DR   A5I1A6, MTNA_CLOBH ;  C1FKZ3, MTNA_CLOBJ ;  B1IJF0, MTNA_CLOBK ;
DR   A7GCV8, MTNA_CLOBL ;  B1KZY3, MTNA_CLOBM ;  A9KIE9, MTNA_CLOPH ;
DR   A3DD27, MTNA_CLOTH ;  C5PBM5, MTNA_COCP7 ;  P0CN41, MTNA_CRYNB ;
DR   P0CN40, MTNA_CRYNJ ;  B1WQH2, MTNA_CYAA5 ;  A9JRE2, MTNA_DANRE ;
DR   Q6BZH5, MTNA_DEBHA ;  Q47AR7, MTNA_DECAR ;  Q3Z937, MTNA_DEHE1 ;
DR   A5FRU8, MTNA_DEHSB ;  Q3ZZT1, MTNA_DEHSC ;  B8FLU0, MTNA_DESAA ;
DR   C6C0F7, MTNA_DESAD ;  B1I2P1, MTNA_DESAP ;  B8J4S7, MTNA_DESDA ;
DR   Q317L9, MTNA_DESDG ;  B8FRM1, MTNA_DESHD ;  Q24UA0, MTNA_DESHY ;
DR   A8ZYA5, MTNA_DESOH ;  A4J678, MTNA_DESRM ;  Q72FX9, MTNA_DESVH ;
DR   B8DQQ9, MTNA_DESVM ;  A1VHH2, MTNA_DESVV ;  B3M098, MTNA_DROAN ;
DR   B3P538, MTNA_DROER ;  B4JRX2, MTNA_DROGR ;  Q9V9X4, MTNA_DROME ;
DR   B4K8A4, MTNA_DROMO ;  B4GYU1, MTNA_DROPE ;  Q29BB3, MTNA_DROPS ;
DR   B4I029, MTNA_DROSE ;  B4QSM8, MTNA_DROSI ;  B4LWZ8, MTNA_DROVI ;
DR   B4NG41, MTNA_DROWI ;  B4PNE2, MTNA_DROYA ;  B7MMH6, MTNA_ECO45 ;
DR   B7NGT8, MTNA_ECOLU ;  Q5B590, MTNA_EMENI ;  A4W7Z1, MTNA_ENT38 ;
DR   A7MKX3, MTNA_ENTS8 ;  B1YIY4, MTNA_EXIS2 ;  A7HN79, MTNA_FERNB ;
DR   C1A6J9, MTNA_GEMAT ;  B5ED21, MTNA_GEOBB ;  Q5L1E6, MTNA_GEOKA ;
DR   B3E3M5, MTNA_GEOLS ;  Q39ZK3, MTNA_GEOMG ;  B9LZ20, MTNA_GEOSF ;
DR   Q746Y8, MTNA_GEOSL ;  C6E6Z4, MTNA_GEOSM ;  C5D7U5, MTNA_GEOSW ;
DR   A4ILL1, MTNA_GEOTN ;  A5G9J7, MTNA_GEOUR ;  Q7NP62, MTNA_GLOVI ;
DR   Q5FQK0, MTNA_GLUOX ;  Q2SE63, MTNA_HAHCH ;  A1WUJ7, MTNA_HALHL ;
DR   B0TH58, MTNA_HELMI ;  A9AYL1, MTNA_HERA2 ;  Q9AYT7, MTNA_HORVU ;
DR   Q9BV20, MTNA_HUMAN ;  B5XZW2, MTNA_KLEP3 ;  A6T656, MTNA_KLEP7 ;
DR   Q6CQP3, MTNA_KLULA ;  B0D0U4, MTNA_LACBS ;  C5DHL1, MTNA_LACTC ;
DR   A4HQ10, MTNA_LEIBR ;  A4ICE5, MTNA_LEIIN ;  Q4Q0R9, MTNA_LEIMA ;
DR   B0SFD6, MTNA_LEPBA ;  Q04RD6, MTNA_LEPBJ ;  Q053E2, MTNA_LEPBL ;
DR   B0SNY3, MTNA_LEPBP ;  Q72T46, MTNA_LEPIC ;  Q8F2A8, MTNA_LEPIN ;
DR   A5DUX4, MTNA_LODEL ;  Q2VZP8, MTNA_MAGSA ;  A0L909, MTNA_MAGSM ;
DR   B6TZD1, MTNA_MAIZE ;  A1U3J9, MTNA_MARAV ;  Q8TUJ1, MTNA_METAC ;
DR   B7KZ66, MTNA_METC4 ;  Q606P2, MTNA_METCA ;  Q57896, MTNA_METJA ;
DR   B8IEX1, MTNA_METNO ;  B1ZL76, MTNA_METPB ;  B8ES44, MTNA_METSB ;
DR   Q2NFJ6, MTNA_METST ;  O27900, MTNA_METTH ;  A8YD90, MTNA_MICAE ;
DR   B0JPT8, MTNA_MICAN ;  A9UQ62, MTNA_MONBE ;  Q2RKL8, MTNA_MOOTA ;
DR   Q9CQT1, MTNA_MOUSE ;  D2VAA9, MTNA_NAEGR ;  B2A5S2, MTNA_NATTJ ;
DR   C7Z638, MTNA_NECH7 ;  A7RF00, MTNA_NEMVE ;  A1CY38, MTNA_NEOFI ;
DR   Q7S4G7, MTNA_NEUCR ;  Q3J8U5, MTNA_NITOC ;  B2J5P6, MTNA_NOSP7 ;
DR   Q8YR82, MTNA_NOSS1 ;  A6X8E9, MTNA_OCHA4 ;  A2ZCP0, MTNA_ORYSI ;
DR   Q0ITU1, MTNA_ORYSJ ;  A4S068, MTNA_OSTLU ;  C1G9Q3, MTNA_PARBD ;
DR   C0S1C8, MTNA_PARBP ;  A6LE92, MTNA_PARD8 ;  C6DCZ1, MTNA_PECCP ;
DR   Q3A2J8, MTNA_PELCD ;  A1ALC1, MTNA_PELPD ;  A5D1G8, MTNA_PELTS ;
DR   B6H5R4, MTNA_PENCW ;  B6QRG1, MTNA_PENMQ ;  C0QUC0, MTNA_PERMH ;
DR   A5DNT0, MTNA_PICGU ;  C4QYS6, MTNA_PICPG ;  A3LN21, MTNA_PICST ;
DR   B2AML6, MTNA_PODAN ;  B9HCR2, MTNA_POPTR ;  B8PBR2, MTNA_POSPM ;
DR   Q48FM6, MTNA_PSE14 ;  A6V2Q6, MTNA_PSEA7 ;  B7V9J7, MTNA_PSEA8 ;
DR   Q02PX5, MTNA_PSEAB ;  Q9HZ65, MTNA_PSEAE ;  Q1IDA4, MTNA_PSEE4 ;
DR   Q4K8M6, MTNA_PSEF5 ;  A4XTE5, MTNA_PSEMY ;  A5W7G2, MTNA_PSEP1 ;
DR   Q3K8T8, MTNA_PSEPF ;  B0KTX5, MTNA_PSEPG ;  Q88M09, MTNA_PSEPK ;
DR   B1J5G5, MTNA_PSEPW ;  Q885T7, MTNA_PSESM ;  Q4ZQ92, MTNA_PSEU2 ;
DR   A4VLZ8, MTNA_PSEU5 ;  Q9UZ16, MTNA_PYRAB ;  Q8U178, MTNA_PYRFU ;
DR   O58433, MTNA_PYRHO ;  B2VZQ8, MTNA_PYRTR ;  Q5HZE4, MTNA_RAT   ;
DR   Q92TI2, MTNA_RHIME ;  Q7UF90, MTNA_RHOBA ;  B6IUC1, MTNA_RHOCS ;
DR   Q21S04, MTNA_RHOFD ;  B9KQ55, MTNA_RHOSK ;  B9RR88, MTNA_RICCO ;
DR   A7NFR2, MTNA_ROSCS ;  A5UQK6, MTNA_ROSS1 ;  B6K4Q2, MTNA_SCHJY ;
DR   O60185, MTNA_SCHPO ;  A7EGZ3, MTNA_SCLS1 ;  A8GAB1, MTNA_SERP5 ;
DR   A6ULQ4, MTNA_SINMW ;  Q028S4, MTNA_SOLUE ;  A9FD66, MTNA_SORC5 ;
DR   P0CI29, MTNA_SORMK ;  B4SP84, MTNA_STRM5 ;  B2FKI7, MTNA_STRMK ;
DR   Q4JB92, MTNA_SULAC ;  Q30P36, MTNA_SULDN ;  B2V8N9, MTNA_SULSY ;
DR   Q67MP0, MTNA_SYMTH ;  Q2LXN1, MTNA_SYNAS ;  Q31LP7, MTNA_SYNE7 ;
DR   A0LIZ1, MTNA_SYNFM ;  B1XJK0, MTNA_SYNP2 ;  Q5N076, MTNA_SYNP6 ;
DR   Q7U4V1, MTNA_SYNPX ;  Q3AWF5, MTNA_SYNS9 ;  Q3AMB7, MTNA_SYNSC ;
DR   Q0AYV4, MTNA_SYNWW ;  P74497, MTNA_SYNY3 ;  B8M7D2, MTNA_TALSN ;
DR   B8C6V3, MTNA_THAPS ;  B7IFW5, MTNA_THEAB ;  Q8DK09, MTNA_THEEB ;
DR   A6LJM7, MTNA_THEM4 ;  Q9X013, MTNA_THEMA ;  B9KA57, MTNA_THENN ;
DR   A5IIM2, MTNA_THEP1 ;  B0K8S2, MTNA_THEP3 ;  B0K2V6, MTNA_THEPX ;
DR   B1LC23, MTNA_THESQ ;  Q72JR1, MTNA_THET2 ;  Q5SJE2, MTNA_THET8 ;
DR   Q8R9L7, MTNA_THETN ;  B5YGA0, MTNA_THEYD ;  B8GRR4, MTNA_THISH ;
DR   Q948X8, MTNA_TOBAC ;  B3RLE6, MTNA_TRIAD ;  Q113K5, MTNA_TRIEI ;
DR   Q383H9, MTNA_TRYB2 ;  D0A8W2, MTNA_TRYB9 ;  C4JWQ7, MTNA_UNCRE ;
DR   A7TSA5, MTNA_VANPO ;  C9SB02, MTNA_VERA1 ;  D7TCD0, MTNA_VITVI ;
DR   Q8PM04, MTNA_XANAC ;  Q3BV11, MTNA_XANC5 ;  Q4UTB3, MTNA_XANC8 ;
DR   B0RUX9, MTNA_XANCB ;  Q8PAB2, MTNA_XANCP ;  Q2P337, MTNA_XANOM ;
DR   B2SIW1, MTNA_XANOP ;  Q5H060, MTNA_XANOR ;  Q4FZP2, MTNA_XENLA ;
DR   Q0VFN1, MTNA_XENTR ;  B2I9S0, MTNA_XYLF2 ;  Q9PAG5, MTNA_XYLFA ;
DR   B0U5G3, MTNA_XYLFM ;  Q87A92, MTNA_XYLFT ;  Q6CGS4, MTNA_YARLI ;
DR   B3LK82, MTNA_YEAS1 ;  C7GXT0, MTNA_YEAS2 ;  B5VTQ8, MTNA_YEAS6 ;
DR   A6ZWZ9, MTNA_YEAS7 ;  C8ZJE0, MTNA_YEAS8 ;  Q06489, MTNA_YEAST ;
DR   A1JP09, MTNA_YERE8 ;  A7FLL1, MTNA_YERP3 ;  B2K633, MTNA_YERPB ;
DR   A9R2Z5, MTNA_YERPG ;  A4TPM9, MTNA_YERPP ;  Q66E16, MTNA_YERPS ;
DR   B1JIK3, MTNA_YERPY ;  C5DU12, MTNA_ZYGRC ;
//
ID   5.3.1.24
DE   Phosphoribosylanthranilate isomerase.
AN   N-(5'-phosphoribosyl)anthranilate isomerase.
AN   PRAI.
CA   N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-
CA   deoxy-D-ribulose 5-phosphate.
CC   -!- In some organisms, this enzyme is part of a multifunctional protein
CC       together with one or more components of the system for biosynthesis
CC       of tryptophan (EC 2.4.2.18, EC 4.1.1.48, EC 4.1.3.27,
CC       and EC 4.2.1.20).
DR   A0QHH8, HIS4_MYCA1 ;  B1MBX5, HIS4_MYCA9 ;  P60579, HIS4_MYCBO ;
DR   A1KJ19, HIS4_MYCBP ;  C1ANM5, HIS4_MYCBT ;  Q9CC56, HIS4_MYCLE ;
DR   P60583, HIS4_MYCPA ;  A3Q127, HIS4_MYCSJ ;  A1UHK4, HIS4_MYCSK ;
DR   Q1B7G8, HIS4_MYCSS ;  A5U2V9, HIS4_MYCTA ;  P60578, HIS4_MYCTU ;
DR   A0PP18, HIS4_MYCUA ;  A1T8W5, HIS4_MYCVP ;  Q82AA1, HIS4_STRAW ;
DR   P16250, HIS4_STRCO ;  B1W0M4, HIS4_STRGG ;  P57366, TRPC_BUCAI ;
DR   P42393, TRPC_BUCAP ;  P59459, TRPC_BUCBP ;  O68427, TRPC_BUCDN ;
DR   Q44603, TRPC_BUCSC ;  P06560, TRPC_CORGL ;  Q8X7B7, TRPC_ECO57 ;
DR   P00909, TRPC_ECOLI ;  P46451, TRPC_HAEIN ;  Q9ZJU8, TRPC_HELPJ ;
DR   O25867, TRPC_HELPY ;  P57855, TRPC_PASMU ;  P24920, TRPC_PHYPR ;
DR   Q8Z7D9, TRPC_SALTI ;  P00910, TRPC_SALTY ;  Q9KST5, TRPC_VIBCH ;
DR   P22098, TRPC_VIBPA ;  Q8ZEG8, TRPC_YERPE ;  Q8PT98, TRPF1_METMA;
DR   Q8PRX4, TRPF2_METMA;  B0CA72, TRPF_ACAM1 ;  P16923, TRPF_ACICA ;
DR   A5FZ94, TRPF_ACICJ ;  B7J4T0, TRPF_ACIF2 ;  Q9Y8T6, TRPF_AERPE ;
DR   B9JG42, TRPF_AGRRK ;  Q8UJB1, TRPF_AGRT5 ;  B9JXV5, TRPF_AGRVS ;
DR   Q0VPI8, TRPF_ALCBS ;  Q3MA33, TRPF_ANAVT ;  O67853, TRPF_AQUAE ;
DR   O28671, TRPF_ARCFU ;  Q757J9, TRPF_ASHGO ;  A8HQ40, TRPF_AZOC5 ;
DR   C1DQD4, TRPF_AZOVD ;  A7Z617, TRPF_BACA2 ;  C3P3T9, TRPF_BACAA ;
DR   C3LAV9, TRPF_BACAC ;  A0RB63, TRPF_BACAH ;  Q81TL9, TRPF_BACAN ;
DR   B7JES9, TRPF_BACC0 ;  Q73BQ8, TRPF_BACC1 ;  B7IM75, TRPF_BACC2 ;
DR   C1ELE9, TRPF_BACC3 ;  B7HH00, TRPF_BACC4 ;  B7I0F1, TRPF_BACC7 ;
DR   B9IU37, TRPF_BACCQ ;  Q81GG6, TRPF_BACCR ;  Q63EC8, TRPF_BACCZ ;
DR   Q9KCB1, TRPF_BACHD ;  Q6HLU5, TRPF_BACHK ;  Q65I34, TRPF_BACLD ;
DR   P70938, TRPF_BACMQ ;  Q5WGS2, TRPF_BACSK ;  P20167, TRPF_BACSU ;
DR   A6L7N0, TRPF_BACV8 ;  A9VJW1, TRPF_BACWK ;  B2IKV4, TRPF_BEII9 ;
DR   Q2KYM1, TRPF_BORA1 ;  Q7WKG8, TRPF_BORBR ;  Q7W923, TRPF_BORPA ;
DR   A9IRJ9, TRPF_BORPD ;  Q7VY68, TRPF_BORPE ;  Q89WE6, TRPF_BRAJA ;
DR   A5E8A5, TRPF_BRASB ;  A4YJI7, TRPF_BRASO ;  C0ZCE4, TRPF_BREBN ;
DR   B2S9A6, TRPF_BRUA1 ;  Q2YQW4, TRPF_BRUA2 ;  Q57AE9, TRPF_BRUAB ;
DR   A9M9U3, TRPF_BRUC2 ;  C0RFZ5, TRPF_BRUMB ;  P67003, TRPF_BRUME ;
DR   B0CJK9, TRPF_BRUSI ;  P67004, TRPF_BRUSU ;  A8FKD6, TRPF_CAMJ8 ;
DR   Q9PIF3, TRPF_CAMJE ;  Q5HWC0, TRPF_CAMJR ;  P43073, TRPF_CANAL ;
DR   P50857, TRPF_CANGA ;  P12289, TRPF_CAUCR ;  B0T692, TRPF_CAUSK ;
DR   B3PFN8, TRPF_CELJU ;  Q3AQC1, TRPF_CHLCH ;  Q822W4, TRPF_CHLCV ;
DR   Q254S9, TRPF_CHLFF ;  Q9PK67, TRPF_CHLMU ;  B3QMF2, TRPF_CHLP8 ;
DR   B3EKM6, TRPF_CHLPB ;  A1BEZ1, TRPF_CHLPD ;  B0B7P4, TRPF_CHLT2 ;
DR   B3QS44, TRPF_CHLT3 ;  Q3KM33, TRPF_CHLTA ;  B0BBV9, TRPF_CHLTB ;
DR   Q8KEH1, TRPF_CHLTE ;  O84331, TRPF_CHLTR ;  Q1QY43, TRPF_CHRSD ;
DR   Q97EF4, TRPF_CLOAB ;  A6LU95, TRPF_CLOB8 ;  B9E150, TRPF_CLOK1 ;
DR   A5N7N9, TRPF_CLOK5 ;  A9KL42, TRPF_CLOPH ;  A3DDS6, TRPF_CLOTH ;
DR   B1WT19, TRPF_CYAA5 ;  B7KC08, TRPF_CYAP7 ;  B7JUH3, TRPF_CYAP8 ;
DR   Q47HQ6, TRPF_DECAR ;  Q3Z6G4, TRPF_DEHE1 ;  Q3ZZ13, TRPF_DEHSC ;
DR   Q9RY28, TRPF_DEIRA ;  B8FA39, TRPF_DESAA ;  C6C1D3, TRPF_DESAD ;
DR   B1I3Z6, TRPF_DESAP ;  B8J162, TRPF_DESDA ;  B8FVH4, TRPF_DESHD ;
DR   Q24SK5, TRPF_DESHY ;  A4J148, TRPF_DESRM ;  Q2N9N2, TRPF_ERYLH ;
DR   B5EBV0, TRPF_GEOBB ;  B3E754, TRPF_GEOLS ;  Q39SQ9, TRPF_GEOMG ;
DR   B9M5M0, TRPF_GEOSF ;  Q74AH7, TRPF_GEOSL ;  C6DYM2, TRPF_GEOSM ;
DR   A4IQ83, TRPF_GEOTN ;  A5GES5, TRPF_GEOUR ;  Q7NML1, TRPF_GLOVI ;
DR   Q0BQI7, TRPF_GRABC ;  Q2SJD2, TRPF_HAHCH ;  A1WY07, TRPF_HALHL ;
DR   B9LQ97, TRPF_HALLT ;  Q5V212, TRPF_HALMA ;  B0R621, TRPF_HALS3 ;
DR   Q9HPG4, TRPF_HALSA ;  P52563, TRPF_HALVD ;  Q875I3, TRPF_HANAN ;
DR   A4G4G1, TRPF_HERAR ;  Q0BWJ4, TRPF_HYPNA ;  Q28LA8, TRPF_JANSC ;
DR   P13997, TRPF_KLULA ;  Q03CY2, TRPF_LACC3 ;  P17218, TRPF_LACCA ;
DR   B3W6W7, TRPF_LACCB ;  Q02002, TRPF_LACLA ;  Q88WI1, TRPF_LACPL ;
DR   Q5X5Q3, TRPF_LEGPA ;  A5IBF6, TRPF_LEGPC ;  Q5ZVY5, TRPF_LEGPH ;
DR   Q5WX33, TRPF_LEGPL ;  Q04RT3, TRPF_LEPBJ ;  Q051T8, TRPF_LEPBL ;
DR   B1XY47, TRPF_LEPCP ;  Q72RH2, TRPF_LEPIC ;  Q8F495, TRPF_LEPIN ;
DR   Q01128, TRPF_LIPST ;  Q92B80, TRPF_LISIN ;  C1KVS6, TRPF_LISMC ;
DR   Q71Z39, TRPF_LISMF ;  B8DHB3, TRPF_LISMH ;  Q8Y6Q5, TRPF_LISMO ;
DR   A0AJ81, TRPF_LISW6 ;  Q2W020, TRPF_MAGSA ;  A0LA38, TRPF_MAGSM ;
DR   A1U0X4, TRPF_MARAV ;  Q0ATJ7, TRPF_MARMM ;  A6VWY4, TRPF_MARMS ;
DR   Q11KK8, TRPF_MESSB ;  A6UW24, TRPF_META3 ;  Q8TLP6, TRPF_METAC ;
DR   A7I4T5, TRPF_METB6 ;  Q57893, TRPF_METJA ;  Q8TXZ9, TRPF_METKA ;
DR   A4FXH5, TRPF_METM5 ;  A9AAU4, TRPF_METM6 ;  A6VFU0, TRPF_METM7 ;
DR   Q6LYI7, TRPF_METMP ;  A2SHS5, TRPF_METPP ;  O27695, TRPF_METTH ;
DR   P26941, TRPF_METTM ;  A0B9D8, TRPF_METTP ;  P14718, TRPF_METVO ;
DR   A6UP16, TRPF_METVS ;  B0JNJ4, TRPF_MICAN ;  Q2RIT8, TRPF_MOOTA ;
DR   Q1CZH4, TRPF_MYXXD ;  Q3IQ37, TRPF_NATPD ;  Q5F9X5, TRPF_NEIG1 ;
DR   B4RJU3, TRPF_NEIG2 ;  A9M342, TRPF_NEIM0 ;  Q9JVD1, TRPF_NEIMA ;
DR   Q9K0C6, TRPF_NEIMB ;  A1KSV1, TRPF_NEIMF ;  Q0AGX6, TRPF_NITEC ;
DR   Q82WI3, TRPF_NITEU ;  Q1QS32, TRPF_NITHX ;  Q2Y7R3, TRPF_NITMU ;
DR   Q3JCB9, TRPF_NITOC ;  A6Q1S6, TRPF_NITSB ;  Q3SWL7, TRPF_NITWN ;
DR   B2J1L6, TRPF_NOSP7 ;  Q8YLL0, TRPF_NOSS1 ;  Q8ESU3, TRPF_OCEIH ;
DR   B6JCP1, TRPF_OLICO ;  A6L9J9, TRPF_PARD8 ;  A1B8L1, TRPF_PARDP ;
DR   A7HPD4, TRPF_PARL1 ;  Q3B533, TRPF_PELLD ;  B4SD44, TRPF_PELPB ;
DR   A1ANJ2, TRPF_PELPD ;  A9BHQ4, TRPF_PETMO ;  O13504, TRPF_PICPA ;
DR   B4S715, TRPF_PROA2 ;  A4SF78, TRPF_PROVI ;  Q48L25, TRPF_PSE14 ;
DR   A6V2W1, TRPF_PSEA7 ;  B7VBQ7, TRPF_PSEA8 ;  Q02PS6, TRPF_PSEAB ;
DR   Q59649, TRPF_PSEAE ;  Q1ICS3, TRPF_PSEE4 ;  Q4KEZ9, TRPF_PSEF5 ;
DR   C3JZS5, TRPF_PSEFS ;  A5W6Y0, TRPF_PSEP1 ;  Q3KF16, TRPF_PSEPF ;
DR   B0KF94, TRPF_PSEPG ;  Q88LE0, TRPF_PSEPK ;  B1J538, TRPF_PSEPW ;
DR   Q87YI1, TRPF_PSESM ;  Q4ZVW1, TRPF_PSEU2 ;  A4VKF4, TRPF_PSEU5 ;
DR   Q9V1G7, TRPF_PYRAB ;  Q8ZV18, TRPF_PYRAE ;  A4WKQ6, TRPF_PYRAR ;
DR   Q8U092, TRPF_PYRFU ;  A1RVT3, TRPF_PYRIL ;  Q9YGB1, TRPF_PYRKO ;
DR   B2U6Z0, TRPF_RALPJ ;  Q8XXX9, TRPF_RALSO ;  B3PVV1, TRPF_RHIE6 ;
DR   Q2KE83, TRPF_RHIEC ;  Q1MND7, TRPF_RHIL3 ;  Q98CN8, TRPF_RHILO ;
DR   B5ZV69, TRPF_RHILW ;  Q92TD0, TRPF_RHIME ;  C3MB98, TRPF_RHISN ;
DR   B6IVY6, TRPF_RHOCS ;  Q2J2G3, TRPF_RHOP2 ;  Q07UH2, TRPF_RHOP5 ;
DR   Q6NDN7, TRPF_RHOPA ;  Q21CB8, TRPF_RHOPB ;  Q13EQ3, TRPF_RHOPS ;
DR   B3Q604, TRPF_RHOPT ;  Q2RNS6, TRPF_RHORT ;  A3PPV2, TRPF_RHOS1 ;
DR   Q9X4E3, TRPF_RHOS4 ;  A7NS83, TRPF_ROSCS ;  A5UYU9, TRPF_ROSS1 ;
DR   Q1AU93, TRPF_RUBXD ;  Q5XQP9, TRPF_SACKU ;  Q2S1Z4, TRPF_SALRD ;
DR   Q1GK79, TRPF_SILST ;  A6UEI0, TRPF_SINMW ;  Q01NI7, TRPF_SOLUE ;
DR   A7X235, TRPF_STAA1 ;  Q2FH65, TRPF_STAA3 ;  Q2FYR5, TRPF_STAA8 ;
DR   Q2YXU8, TRPF_STAAB ;  Q5HG48, TRPF_STAAC ;  P67005, TRPF_STAAM ;
DR   P67006, TRPF_STAAN ;  Q6GH34, TRPF_STAAR ;  Q6G9I8, TRPF_STAAS ;
DR   P67007, TRPF_STAAW ;  B9DP52, TRPF_STACT ;  Q5HPH1, TRPF_STAEQ ;
DR   Q8CSN5, TRPF_STAES ;  Q4L678, TRPF_STAHJ ;  A8AW04, TRPF_STRGC ;
DR   B4SQV5, TRPF_STRM5 ;  B2FNZ5, TRPF_STRMK ;  Q8DVF4, TRPF_STRMU ;
DR   Q04IY8, TRPF_STRP2 ;  B5E7M4, TRPF_STRP4 ;  C1C967, TRPF_STRP7 ;
DR   B1I7S8, TRPF_STRPI ;  B8ZN60, TRPF_STRPJ ;  Q97P31, TRPF_STRPN ;
DR   Q8DNM7, TRPF_STRR6 ;  C1CG43, TRPF_STRZJ ;  C1CMD4, TRPF_STRZP ;
DR   C1CT52, TRPF_STRZT ;  Q4J8X6, TRPF_SULAC ;  A6QC86, TRPF_SULNB ;
DR   P50386, TRPF_SULSO ;  B2V7Q4, TRPF_SULSY ;  Q67PJ5, TRPF_SYMTH ;
DR   Q2LUD8, TRPF_SYNAS ;  Q31R79, TRPF_SYNE7 ;  Q2JW90, TRPF_SYNJA ;
DR   Q2JPT2, TRPF_SYNJB ;  B1XNB2, TRPF_SYNP2 ;  Q5N322, TRPF_SYNP6 ;
DR   Q0B004, TRPF_SYNWW ;  P74435, TRPF_SYNY3 ;  Q8DGP3, TRPF_THEEB ;
DR   Q56320, TRPF_THEMA ;  B9K6Z3, TRPF_THENN ;  A5IKT2, TRPF_THEP1 ;
DR   B0K8T5, TRPF_THEP3 ;  B0K2U0, TRPF_THEPX ;  B1LA13, TRPF_THESQ ;
DR   Q8R9M8, TRPF_THETN ;  Q979V6, TRPF_THEVO ;  B5YKL4, TRPF_THEYD ;
DR   Q3SHL8, TRPF_THIDA ;  Q10XS2, TRPF_TRIEI ;  Q0W628, TRPF_UNCMA ;
DR   B1GZC1, TRPF_UNCTG ;  Q8PJ26, TRPF_XANAC ;  Q3BRL1, TRPF_XANC5 ;
DR   Q4UWD4, TRPF_XANC8 ;  B0RR82, TRPF_XANCB ;  Q8P7R6, TRPF_XANCP ;
DR   Q2P0U0, TRPF_XANOM ;  B2SVN9, TRPF_XANOP ;  Q5GXR3, TRPF_XANOR ;
DR   B2I9J1, TRPF_XYLF2 ;  Q9PDK5, TRPF_XYLFA ;  B0U6K5, TRPF_XYLFM ;
DR   Q87DS0, TRPF_XYLFT ;  P00912, TRPF_YEAST ;  Q9HFW8, TRPF_ZYGBA ;
DR   Q5NPZ5, TRPF_ZYMMO ;  Q9S3U4, TRPF_ZYMMP ;  P18483, TRPG_ASPAW ;
DR   P05328, TRPG_ASPNG ;  Q92411, TRPG_COCHE ;  P0CN87, TRPG_CRYNB ;
DR   P0CN86, TRPG_CRYNJ ;  P27710, TRPG_CRYNV ;  P06531, TRPG_EMENI ;
DR   P00908, TRPG_NEUCR ;  P24773, TRPG_PENCH ;  P25170, TRPG_PHACH ;
DR   P20409, TRPG_PHYBL ;  Q92370, TRPG_SCHPO ;
//
ID   5.3.1.25
DE   L-fucose isomerase.
CA   L-fucose = L-fuculose.
DR   Q5LIN8, FUCI_BACFN ;  Q64ZS4, FUCI_BACFR ;  Q9RQ13, FUCI_BACTN ;
DR   A6L048, FUCI_BACV8 ;  A8AP13, FUCI_CITK8 ;  Q8XNL5, FUCI_CLOPE ;
DR   A7ZQP6, FUCI_ECO24 ;  B7UHL8, FUCI_ECO27 ;  B7MLC3, FUCI_ECO45 ;
DR   B7LEY2, FUCI_ECO55 ;  Q8X6R5, FUCI_ECO57 ;  B5Z4C2, FUCI_ECO5E ;
DR   B7NVV0, FUCI_ECO7I ;  B7MZ98, FUCI_ECO81 ;  B7LXL8, FUCI_ECO8A ;
DR   C4ZZV7, FUCI_ECOBW ;  B1XDL1, FUCI_ECODH ;  A8A3T7, FUCI_ECOHS ;
DR   A1AEY9, FUCI_ECOK1 ;  Q0TE57, FUCI_ECOL5 ;  Q8FEE7, FUCI_ECOL6 ;
DR   B1IU39, FUCI_ECOLC ;  P69922, FUCI_ECOLI ;  B7N736, FUCI_ECOLU ;
DR   B6I6K0, FUCI_ECOSE ;  B1LQZ6, FUCI_ECOSM ;  Q1R7N8, FUCI_ECOUT ;
DR   A5UAS8, FUCI_HAEIE ;  P44779, FUCI_HAEIN ;  B5XUY5, FUCI_KLEP3 ;
DR   A6TD83, FUCI_KLEP7 ;  B5F4S3, FUCI_SALA4 ;  A9MSA6, FUCI_SALAR ;
DR   Q57KE0, FUCI_SALCH ;  B5FTY1, FUCI_SALDC ;  B5QWR0, FUCI_SALEP ;
DR   B5RDV4, FUCI_SALG2 ;  B4TGN3, FUCI_SALHS ;  B4T4X1, FUCI_SALNS ;
DR   Q5PEK9, FUCI_SALPA ;  A9N2J1, FUCI_SALPB ;  C0PXG5, FUCI_SALPC ;
DR   B5BF31, FUCI_SALPK ;  B4TUJ7, FUCI_SALSV ;  Q8Z429, FUCI_SALTI ;
DR   Q8ZMC6, FUCI_SALTY ;  Q32CB6, FUCI_SHIDS ;  Q0T157, FUCI_SHIF8 ;
DR   P69923, FUCI_SHIFL ;  Q04I16, FUCI_STRP2 ;  C1CB02, FUCI_STRP7 ;
DR   B1I9W8, FUCI_STRPI ;  B8ZPZ6, FUCI_STRPJ ;  Q97N97, FUCI_STRPN ;
DR   B2INH7, FUCI_STRPS ;  Q8DN24, FUCI_STRR6 ;  C1CHF7, FUCI_STRZJ ;
DR   C1CND0, FUCI_STRZP ;  C1CU77, FUCI_STRZT ;  Q7MJI2, FUCI_VIBVY ;
//
ID   5.3.1.26
DE   Galactose-6-phosphate isomerase.
CA   D-galactose 6-phosphate = D-tagatose 6-phosphate.
CC   -!- Involved in the tagatose 6-phosphate pathway of lactose catabolism in
CC       bacteria.
DR   Q8E4R5, LACA1_STRA3;  Q99YH1, LACA1_STRP1;  P0DC04, LACA1_STRP3;
DR   Q5XAI1, LACA1_STRP6;  Q8NZV6, LACA1_STRP8;  Q48RV9, LACA1_STRPM;
DR   P0DC05, LACA1_STRPQ;  Q8E344, LACA2_STRA3;  Q99Y12, LACA2_STRP1;
DR   P0DC06, LACA2_STRP3;  Q5X9Y1, LACA2_STRP6;  Q7CMS1, LACA2_STRP8;
DR   Q48RC2, LACA2_STRPM;  P0DC07, LACA2_STRPQ;  Q97F01, LACA_CLOAB ;
DR   Q8XNK7, LACA_CLOPE ;  Q833U3, LACA_ENTFA ;  P23494, LACA_LACLA ;
DR   A7X579, LACA_STAA1 ;  A6U3S5, LACA_STAA2 ;  Q2FET7, LACA_STAA3 ;
DR   Q2G2R4, LACA_STAA8 ;  A5IUY4, LACA_STAA9 ;  Q2YYJ3, LACA_STAAB ;
DR   Q5HE10, LACA_STAAC ;  A6QJ39, LACA_STAAE ;  P65250, LACA_STAAM ;
DR   P65251, LACA_STAAN ;  Q6GEN4, LACA_STAAR ;  Q6G7B9, LACA_STAAS ;
DR   A8Z305, LACA_STAAT ;  P0C1R5, LACA_STAAU ;  P65252, LACA_STAAW ;
DR   Q5HM35, LACA_STAEQ ;  Q8CRJ2, LACA_STAES ;  Q4L874, LACA_STAHJ ;
DR   Q3JZ18, LACA_STRA1 ;  Q8DXC0, LACA_STRA5 ;  C0M8Q6, LACA_STRE4 ;
DR   B4U1F8, LACA_STREM ;  P26423, LACA_STRMU ;  Q04KC1, LACA_STRP2 ;
DR   B5E4T2, LACA_STRP4 ;  C1C7G2, LACA_STRP7 ;  B1IBZ7, LACA_STRPI ;
DR   B8ZQ66, LACA_STRPJ ;  Q97QL0, LACA_STRPN ;  B2IPT5, LACA_STRPS ;
DR   Q8DPN9, LACA_STRR6 ;  C0MDX6, LACA_STRS7 ;  C1CEF4, LACA_STRZJ ;
DR   C1CKT9, LACA_STRZP ;  C1CRA4, LACA_STRZT ;  Q8E4R6, LACB1_STRA3;
DR   Q99YH2, LACB1_STRP1;  P0DC08, LACB1_STRP3;  Q5XAI2, LACB1_STRP6;
DR   Q8NZV7, LACB1_STRP8;  Q48RW0, LACB1_STRPM;  P0DC09, LACB1_STRPQ;
DR   Q8E345, LACB2_STRA3;  Q99Y13, LACB2_STRP1;  P0DC10, LACB2_STRP3;
DR   Q5X9Y2, LACB2_STRP6;  Q8NZD8, LACB2_STRP8;  Q48RC3, LACB2_STRPM;
DR   P0DC11, LACB2_STRPQ;  Q97F02, LACB_CLOAB ;  Q8XNK6, LACB_CLOPE ;
DR   Q833U4, LACB_ENTFA ;  P23495, LACB_LACLA ;  A7X578, LACB_STAA1 ;
DR   A6U3S4, LACB_STAA2 ;  Q2FET8, LACB_STAA3 ;  Q2G2R0, LACB_STAA8 ;
DR   A5IUY3, LACB_STAA9 ;  Q2YYJ4, LACB_STAAB ;  Q5HE11, LACB_STAAC ;
DR   A6QJ38, LACB_STAAE ;  P65646, LACB_STAAM ;  P65647, LACB_STAAN ;
DR   Q6GEN5, LACB_STAAR ;  Q6G7C0, LACB_STAAS ;  A8YYG1, LACB_STAAT ;
DR   P0C1R6, LACB_STAAU ;  P68797, LACB_STAAW ;  Q5HM36, LACB_STAEQ ;
DR   Q8CRJ3, LACB_STAES ;  Q4L873, LACB_STAHJ ;  Q3JZ19, LACB_STRA1 ;
DR   Q8DXC1, LACB_STRA5 ;  C0M8Q7, LACB_STRE4 ;  B4U1F9, LACB_STREM ;
DR   P26424, LACB_STRMU ;  Q04KC2, LACB_STRP2 ;  B5E4T1, LACB_STRP4 ;
DR   C1C7G1, LACB_STRP7 ;  Q1J9U7, LACB_STRPB ;  Q1JJZ6, LACB_STRPC ;
DR   A2RD12, LACB_STRPG ;  B1IBZ6, LACB_STRPI ;  B8ZQ65, LACB_STRPJ ;
DR   Q97QL1, LACB_STRPN ;  B2IPT6, LACB_STRPS ;  Q8DPP0, LACB_STRR6 ;
DR   A4W1H6, LACB_STRS2 ;  C0MDX5, LACB_STRS7 ;  A3CPH6, LACB_STRSV ;
DR   A4VV69, LACB_STRSY ;  C1CEF3, LACB_STRZJ ;  C1CKT8, LACB_STRZP ;
DR   C1CRA5, LACB_STRZT ;
//
ID   5.3.1.27
DE   6-phospho-3-hexuloisomerase.
AN   3-hexulose-6-phosphate isomerase.
AN   6-phospho-3-hexulose isomerase.
AN   PHI.
AN   Phospho-3-hexuloisomerase.
CA   D-arabino-hex-3-ulose 6-phosphate = D-fructose 6-phosphate.
CC   -!- This enzyme, along with EC 4.1.2.43, plays a key role in the
CC       ribulose-monophosphate cycle of formaldehyde fixation, which is
CC       present in many microorganisms that are capable of utilizing
CC       C1-compounds.
CC   -!- The hyperthermophilic and anaerobic archaeon Pyrococcus horikoshii
CC       OT3 constitutively produces a bifunctional enzyme that sequentially
CC       catalyzes the reactions of EC 4.1.2.43 and this enzyme.
PR   PROSITE; PDOC51464;
DR   P42404, PHI_BACSU  ;  Q9S0X3, PHI_METAM  ;  Q58644, PHI_METJA  ;
DR   Q9LBW5, PHI_MYCGS  ;
//
ID   5.3.1.28
DE   D-sedoheptulose 7-phosphate isomerase.
AN   Phosphoheptose isomerase.
AN   Sedoheptulose-7-phosphate isomerase.
CA   D-sedoheptulose 7-phosphate = D-glycero-D-manno-heptose 7-phosphate.
CC   -!- In Gram-negative bacteria the enzyme is involved in biosynthesis of
CC       ADP-L-glycero-beta-D-manno-heptose, which is utilized for assembly of
CC       the lipopolysaccharide inner core.
CC   -!- In Gram-positive bacteria the enzyme is involved in biosynthesis of
CC       GDP-D-glycero-alpha-D-manno-heptose, which is required for assembly
CC       of S-layer glycoprotein.
DR   Q9PNE6, GMHA1_CAMJE;  Q9PMN3, GMHA2_CAMJE;  A3N0F8, GMHA_ACTP2 ;
DR   B3H1D8, GMHA_ACTP7 ;  B0BP79, GMHA_ACTPJ ;  A6VLR0, GMHA_ACTSZ ;
DR   A0KIK9, GMHA_AERHH ;  A4SPH9, GMHA_AERS4 ;  B2UNE0, GMHA_AKKM8 ;
DR   Q0A6I9, GMHA_ALHEH ;  B4RXI5, GMHA_ALTMD ;  Q9AGY7, GMHA_ANETH ;
DR   O67054, GMHA_AQUAE ;  A8EVR5, GMHA_ARCB4 ;  Q5P6Y3, GMHA_AROAE ;
DR   A1K3T2, GMHA_AZOSB ;  C1DQ86, GMHA_AZOVD ;  Q2KU87, GMHA_BORA1 ;
DR   A5EN81, GMHA_BRASB ;  A4YYB9, GMHA_BRASO ;  B8D943, GMHA_BUCA5 ;
DR   P57338, GMHA_BUCAI ;  Q8K9R9, GMHA_BUCAP ;  B8D7E7, GMHA_BUCAT ;
DR   Q9AI36, GMHA_BURMA ;  Q3JP41, GMHA_BURP1 ;  Q93UJ2, GMHA_BURPS ;
DR   A7ZE25, GMHA_CAMC1 ;  A8FMK7, GMHA_CAMJ8 ;  B9KFJ1, GMHA_CAMLR ;
DR   Q3AUB6, GMHA_CHLCH ;  B3EHV1, GMHA_CHLL2 ;  B3QL68, GMHA_CHLP8 ;
DR   A1BJG0, GMHA_CHLPD ;  Q8KAW3, GMHA_CHLTE ;  Q1QVF5, GMHA_CHRSD ;
DR   Q97EQ4, GMHA_CLOAB ;  Q47VU0, GMHA_COLP3 ;  B6J4R0, GMHA_COXB1 ;
DR   B6J2U5, GMHA_COXB2 ;  A9KBY6, GMHA_COXBN ;  A9NAA5, GMHA_COXBR ;
DR   Q83AY4, GMHA_COXBU ;  B1WYG5, GMHA_CYAA5 ;  Q11Y71, GMHA_CYTH3 ;
DR   Q47IS3, GMHA_DECAR ;  C6C0L8, GMHA_DESAD ;  B8J0B1, GMHA_DESDA ;
DR   C4XJU6, GMHA_DESMR ;  Q72AV1, GMHA_DESVH ;  B8DKW0, GMHA_DESVM ;
DR   A7ZHY1, GMHA_ECO24 ;  B7UJB5, GMHA_ECO27 ;  B7MC74, GMHA_ECO45 ;
DR   B7LHF3, GMHA_ECO55 ;  P63225, GMHA_ECO57 ;  B5Z0M1, GMHA_ECO5E ;
DR   B7NKV9, GMHA_ECO7I ;  B7MQ59, GMHA_ECO81 ;  B7M252, GMHA_ECO8A ;
DR   C4ZRV8, GMHA_ECOBW ;  B1XD84, GMHA_ECODH ;  A7ZWI6, GMHA_ECOHS ;
DR   Q0TL93, GMHA_ECOL5 ;  P63226, GMHA_ECOL6 ;  B1IPP6, GMHA_ECOLC ;
DR   P63224, GMHA_ECOLI ;  B7N8A8, GMHA_ECOLU ;  B6HZW0, GMHA_ECOSE ;
DR   B1LHM8, GMHA_ECOSM ;  C5B7W2, GMHA_EDWI9 ;  A4W6W5, GMHA_ENT38 ;
DR   A7MI45, GMHA_ENTS8 ;  Q6D1H3, GMHA_ERWCT ;  B2VIQ7, GMHA_ERWT9 ;
DR   B7LW94, GMHA_ESCF3 ;  Q8R6A2, GMHA_FUSNN ;  B5EGN2, GMHA_GEOBB ;
DR   B3E5N0, GMHA_GEOLS ;  Q39X62, GMHA_GEOMG ;  B9M5R7, GMHA_GEOSF ;
DR   Q74BF4, GMHA_GEOSL ;  C6E6C5, GMHA_GEOSM ;  A5G5G9, GMHA_GEOUR ;
DR   Q0BRW8, GMHA_GRABC ;  O87340, GMHA_HAEDU ;  Q4QLB7, GMHA_HAEI8 ;
DR   A5UCS8, GMHA_HAEIE ;  A5UIU8, GMHA_HAEIG ;  P45093, GMHA_HAEIN ;
DR   B8F3D3, GMHA_HAEPS ;  B0USS3, GMHA_HAES2 ;  A1WYV6, GMHA_HALHL ;
DR   C4K7X8, GMHA_HAMD5 ;  Q7VFZ4, GMHA_HELHP ;  B6JM81, GMHA_HELP2 ;
DR   Q1CT15, GMHA_HELPH ;  Q9ZKZ1, GMHA_HELPJ ;  B2USX3, GMHA_HELPS ;
DR   O25528, GMHA_HELPY ;  B5Y1F4, GMHA_KLEP3 ;  A6T518, GMHA_KLEP7 ;
DR   C1D5I3, GMHA_LARHH ;  B0SHL8, GMHA_LEPBA ;  Q04RN4, GMHA_LEPBJ ;
DR   Q051Y7, GMHA_LEPBL ;  B0SR27, GMHA_LEPBP ;  Q72RC1, GMHA_LEPIC ;
DR   Q8F4E9, GMHA_LEPIN ;  Q2WBD9, GMHA_MAGSA ;  Q60CC5, GMHA_METCA ;
DR   Q58731, GMHA_METJA ;  A2SMC9, GMHA_METPP ;  P0A605, GMHA_MYCBO ;
DR   A1KET4, GMHA_MYCBP ;  C1AJD9, GMHA_MYCBT ;  A5TYI7, GMHA_MYCTA ;
DR   P0A604, GMHA_MYCTU ;  Q5F5E3, GMHA_NEIG1 ;  B4RQP9, GMHA_NEIG2 ;
DR   A9M479, GMHA_NEIM0 ;  P0A0Y5, GMHA_NEIMA ;  P0A0Y6, GMHA_NEIMB ;
DR   A1KWG6, GMHA_NEIMF ;  A6Q4Z5, GMHA_NITSB ;  P57814, GMHA_PASMU ;
DR   C6DCY7, GMHA_PECCP ;  Q3A538, GMHA_PELCD ;  B4SGD2, GMHA_PELPB ;
DR   A1AV13, GMHA_PELPD ;  Q7N7F7, GMHA_PHOLL ;  B4EUT1, GMHA_PROMH ;
DR   A4SGN4, GMHA_PROVI ;  Q15PJ1, GMHA_PSEA6 ;  A6VB98, GMHA_PSEA7 ;
DR   B7UZK3, GMHA_PSEA8 ;  Q02H15, GMHA_PSEAB ;  Q9HVZ0, GMHA_PSEAE ;
DR   Q1I5A5, GMHA_PSEE4 ;  C3KBY0, GMHA_PSEFS ;  A5W8R3, GMHA_PSEP1 ;
DR   Q3K731, GMHA_PSEPF ;  B0KFT9, GMHA_PSEPG ;  B1J1X7, GMHA_PSEPW ;
DR   Q4ZNX7, GMHA_PSEU2 ;  A1SUJ5, GMHA_PSYIN ;  Q2RR43, GMHA_RHORT ;
DR   A5UVV6, GMHA_ROSS1 ;  B5EWJ3, GMHA_SALA4 ;  Q57SU4, GMHA_SALCH ;
DR   B5FJW2, GMHA_SALDC ;  B5R470, GMHA_SALEP ;  B5R5Q7, GMHA_SALG2 ;
DR   B4T7P3, GMHA_SALHS ;  B4SVV2, GMHA_SALNS ;  Q5PF73, GMHA_SALPA ;
DR   A9MY16, GMHA_SALPB ;  B5BDQ9, GMHA_SALPK ;  B4TYM6, GMHA_SALSV ;
DR   P63222, GMHA_SALTI ;  P63223, GMHA_SALTY ;  A8GAB6, GMHA_SERP5 ;
DR   A1SB02, GMHA_SHEAM ;  B8EBE0, GMHA_SHEB2 ;  A3DA03, GMHA_SHEB5 ;
DR   A6WTQ0, GMHA_SHEB8 ;  A9L683, GMHA_SHEB9 ;  Q12SK9, GMHA_SHEDO ;
DR   Q088R5, GMHA_SHEFN ;  B0TL65, GMHA_SHEHH ;  A3Q9E9, GMHA_SHELP ;
DR   Q8EK08, GMHA_SHEON ;  A8GZ41, GMHA_SHEPA ;  A4YBR9, GMHA_SHEPC ;
DR   B8CNK0, GMHA_SHEPW ;  A0L231, GMHA_SHESA ;  A8G184, GMHA_SHESH ;
DR   Q0HDW8, GMHA_SHESM ;  Q0I041, GMHA_SHESR ;  A1RPP6, GMHA_SHESW ;
DR   B1KP81, GMHA_SHEWM ;  B2U3R4, GMHA_SHIB3 ;  Q325S4, GMHA_SHIBS ;
DR   Q32JN6, GMHA_SHIDS ;  P63227, GMHA_SHIFL ;  Q3Z5B4, GMHA_SHISS ;
DR   Q2NVF5, GMHA_SODGM ;  Q9Z5B6, GMHA_STRCO ;  Q30T29, GMHA_SULDN ;
DR   Q55797, GMHA_SYNY3 ;  Q9HJV9, GMHA_THEAC ;  Q97A25, GMHA_THEVO ;
DR   B5YJT7, GMHA_THEYD ;  Q3SMI5, GMHA_THIDA ;  C4LC62, GMHA_TOLAT ;
DR   Q9KPY2, GMHA_VIBCH ;  Q87MG7, GMHA_VIBPA ;  Q8DBC5, GMHA_VIBVU ;
DR   Q7M9U0, GMHA_WOLSU ;  A1JP02, GMHA_YERE8 ;  A7FLK2, GMHA_YERP3 ;
DR   Q1C4C6, GMHA_YERPA ;  Q8ZBY7, GMHA_YERPE ;  A9R2Y9, GMHA_YERPG ;
DR   Q1CLE7, GMHA_YERPN ;  A4TPM1, GMHA_YERPP ;  B1JIJ3, GMHA_YERPY ;
//
ID   5.3.1.n1
DE   5-deoxy-glucuronate isomerase.
AN   5DG isomerase.
CA   5-deoxy-glucuronic acid = 5-dehydro-2-deoxy-D-gluconic acid.
CC   -!- Part of the myo-inositol/D-chiro-inositol degradation pathway leading
CC       to acetyl-CoA together with EC 1.1.1.n6, EC 5.3.99.n1, EC 4.2.1.44,
CC       EC 3.7.1.n2, EC 2.7.1.92, EC 4.1.2.29 and EC 1.2.1.18.
DR   A7ZAI0, IOLB_BACA2 ;  Q9KAG7, IOLB_BACHD ;  Q65D01, IOLB_BACLD ;
DR   A7BJC5, IOLB_BACNA ;  Q5WKZ0, IOLB_BACSK ;  P42413, IOLB_BACSU ;
DR   Q5KYR2, IOLB_GEOKA ;  A4IPB4, IOLB_GEOTN ;  A5YBJ4, IOLB_LACCA ;
DR   Q92EQ6, IOLB_LISIN ;  C1KZA0, IOLB_LISMC ;  Q723T0, IOLB_LISMF ;
DR   B8DCT7, IOLB_LISMH ;  Q8Y9Y3, IOLB_LISMO ;
//
ID   5.3.2.1
DE   Phenylpyruvate tautomerase.
AN   Phenylpyruvate keto--enol tautomerase.
AN   Phenylpyruvic keto--enol isomerase.
CA   Keto-phenylpyruvate = enol-phenylpyruvate.
CC   -!- Also acts on other arylpyruvates.
DR   P91850, MIFH_BRUMA ;  P81529, MIFH_TRISP ;  P81748, MIFH_TRITR ;
DR   O44786, MIFH_WUCBA ;  P80177, MIF_BOVIN  ;  Q02960, MIF_CHICK  ;
DR   P14174, MIF_HUMAN  ;  Q4R549, MIF_MACFA  ;  Q6DN04, MIF_MACMU  ;
DR   O55052, MIF_MERUN  ;  P34884, MIF_MOUSE  ;  P80928, MIF_PIG    ;
DR   P30904, MIF_RAT    ;  Q1ZZU7, MIF_SHEEP  ;  Q76BK2, MIF_XENLA  ;
DR   A9JSE7, MIF_XENTR  ;
//
ID   5.3.2.2
DE   Oxaloacetate tautomerase.
AN   Oxalacetic keto--enol isomerase.
AN   Oxaloacetate keto--enol tautomerase.
CA   Keto-oxaloacetate = enol-oxaloacetate.
//
ID   5.3.2.n1
DE   2,3-diketo-5-methylthiopentyl-1-phosphate enolase.
AN   DK-MTP-1-P enolase.
AN   RuBisCO-like protein.
CA   5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-
CA   oxopent-1-enyl phosphate.
CC   -!- In some species, this reaction and the reaction catalyzed by
CC       EC 3.1.3.n4 are catalyzed by EC 3.1.3.77.
DR   A7Z3X4, MTNW_BACA2 ;  C3P745, MTNW_BACAA ;  C3LIA6, MTNW_BACAC ;
DR   A0RI42, MTNW_BACAH ;  Q81MJ2, MTNW_BACAN ;  B7JL16, MTNW_BACC0 ;
DR   Q731R2, MTNW_BACC1 ;  B7IWE8, MTNW_BACC2 ;  C1EQR1, MTNW_BACC3 ;
DR   B7H927, MTNW_BACC4 ;  B7HN14, MTNW_BACC7 ;  A7GS60, MTNW_BACCN ;
DR   B9IWP9, MTNW_BACCQ ;  Q819E8, MTNW_BACCR ;  Q635P3, MTNW_BACCZ ;
DR   Q6HEC9, MTNW_BACHK ;  Q65KJ8, MTNW_BACLD ;  A8FCG8, MTNW_BACP2 ;
DR   Q5WH45, MTNW_BACSK ;  O31666, MTNW_BACSU ;  A9VFD9, MTNW_BACWK ;
DR   B1YIY2, MTNW_EXIS2 ;  Q5L1E2, MTNW_GEOKA ;  C5D7U9, MTNW_GEOSW ;
DR   A4ILL5, MTNW_GEOTN ;  A8YER2, MTNW_MICAE ;  B0JTU1, MTNW_MICAN ;
//
ID   5.3.3.1
DE   Steroid Delta-isomerase.
AN   3-oxosteroid isomerase.
AN   Delta(5)-3-keto steroid isomerase.
AN   Delta(5)-3-ketosteroid isomerase.
AN   Delta(5)-3-oxosteroid isomerase.
AN   Delta(5)-steroid isomerase.
AN   Hydroxysteroid isomerase.
AN   Steroid isomerase.
CA   A 3-oxo-Delta(5)-steroid = a 3-oxo-Delta(4)-steroid.
DR   P14060, 3BHS1_HUMAN;  P27365, 3BHS1_MACMU;  Q60555, 3BHS1_MESAU;
DR   P24815, 3BHS1_MOUSE;  P22071, 3BHS1_RAT  ;  P26439, 3BHS2_HUMAN;
DR   Q64421, 3BHS2_MESAU;  P26149, 3BHS2_MOUSE;  P22072, 3BHS2_RAT  ;
DR   P26150, 3BHS3_MOUSE;  Q62878, 3BHS4_RAT  ;  O35469, 3BHS6_MOUSE;
DR   P14893, 3BHS_BOVIN ;  Q5IFP1, 3BHS_CANFA ;  Q67477, 3BHS_FOWPN ;
DR   O46516, 3BHS_HORSE ;  O53454, 3BHS_MYCTU ;  Q9N119, 3BHS_PIG   ;
DR   O57245, 3BHS_VACCA ;  P21097, 3BHS_VACCC ;  P26670, 3BHS_VACCW ;
DR   Q89187, 3BHS_VAR67 ;  P00947, SDIS_COMTE ;  P77816, SDIS_NOCSI ;
DR   P07445, SDIS_PSEPU ;
//
ID   5.3.3.2
DE   Isopentenyl-diphosphate Delta-isomerase.
AN   IPP isomerase.
AN   Isopentenylpyrophosphate Delta-isomerase.
AN   Isopentenylpyrophosphate isomerase.
AN   Methylbutenylpyrophosphate isomerase.
CA   Isopentenyl diphosphate = dimethylallyl diphosphate.
CF   FMN or FAD; Magnesium or manganese or calcium.
DR   Q38929, IDI1_ARATH ;  Q5P011, IDI1_AROAE ;  Q1LZ95, IDI1_BOVIN ;
DR   O48964, IDI1_CAMAC ;  Q39472, IDI1_CLABR ;  Q13907, IDI1_HUMAN ;
DR   Q4R4W5, IDI1_MACFA ;  O35586, IDI1_MESAU ;  P58044, IDI1_MOUSE ;
DR   O42641, IDI1_PHARH ;  Q7N1V4, IDI1_PHOLL ;  Q5R8R6, IDI1_PONAB ;
DR   O35760, IDI1_RAT   ;  Q10132, IDI1_SCHPO ;  P15496, IDI1_YEAST ;
DR   Q9YB30, IDI2_AERPE ;  Q3MAB0, IDI2_ANAVT ;  Q42553, IDI2_ARATH ;
DR   O27997, IDI2_ARCFU ;  Q5NWG5, IDI2_AROAE ;  A7Z638, IDI2_BACA2 ;
DR   C3P586, IDI2_BACAA ;  C3L9F9, IDI2_BACAC ;  A0RBV4, IDI2_BACAH ;
DR   Q81SX4, IDI2_BACAN ;  B7JGY4, IDI2_BACC0 ;  Q73AZ6, IDI2_BACC1 ;
DR   B7IP77, IDI2_BACC2 ;  C1EMZ6, IDI2_BACC3 ;  B7HHQ2, IDI2_BACC4 ;
DR   B7HL09, IDI2_BACC7 ;  A7GN36, IDI2_BACCN ;  B9IVM2, IDI2_BACCQ ;
DR   Q81FS0, IDI2_BACCR ;  Q63DN3, IDI2_BACCZ ;  Q6HL56, IDI2_BACHK ;
DR   Q65I10, IDI2_BACLD ;  A8FEM3, IDI2_BACP2 ;  P50740, IDI2_BACSU ;
DR   A9VMA7, IDI2_BACWK ;  Q6MMK2, IDI2_BDEBA ;  Q0SMG9, IDI2_BORAP ;
DR   O51627, IDI2_BORBU ;  Q660I6, IDI2_BORGA ;  O48965, IDI2_CAMAC ;
DR   Q3AQM4, IDI2_CHLCH ;  B3EFC7, IDI2_CHLL2 ;  B3QQG6, IDI2_CHLP8 ;
DR   A1BDG7, IDI2_CHLPD ;  Q8KFR5, IDI2_CHLTE ;  Q39471, IDI2_CLABR ;
DR   Q39664, IDI2_CLAXA ;  Q9RVE2, IDI2_DEIRA ;  Q837E2, IDI2_ENTFA ;
DR   A7MPA0, IDI2_ENTS8 ;  Q01335, IDI2_ESCVU ;  C5D3G3, IDI2_GEOSW ;
DR   Q9HHE4, IDI2_HALSA ;  Q9BXS1, IDI2_HUMAN ;  A8AAN4, IDI2_IGNH4 ;
DR   Q9KWF6, IDI2_KITGR ;  Q03S19, IDI2_LACBA ;  Q038V3, IDI2_LACC3 ;
DR   B3WEJ5, IDI2_LACCB ;  Q9CIF5, IDI2_LACLA ;  Q88WB6, IDI2_LACPL ;
DR   A5VK00, IDI2_LACRD ;  B2G7E3, IDI2_LACRJ ;  Q38X74, IDI2_LACSS ;
DR   Q5X3K0, IDI2_LEGPA ;  A5IDN6, IDI2_LEGPC ;  Q5ZTV7, IDI2_LEGPH ;
DR   Q5WUY8, IDI2_LEGPL ;  Q92BX2, IDI2_LISIN ;  C1L2T9, IDI2_LISMC ;
DR   Q71ZT7, IDI2_LISMF ;  B8DFU4, IDI2_LISMH ;  Q8Y7A5, IDI2_LISMO ;
DR   A0AII5, IDI2_LISW6 ;  A6UW89, IDI2_META3 ;  Q8TT35, IDI2_METAC ;
DR   A7IAG4, IDI2_METB6 ;  Q46CL4, IDI2_METBF ;  Q12TH8, IDI2_METBU ;
DR   Q58272, IDI2_METJA ;  Q8TX99, IDI2_METKA ;  Q8PW37, IDI2_METMA ;
DR   Q6M174, IDI2_METMP ;  A4YIM3, IDI2_METS5 ;  O26154, IDI2_METTH ;
DR   A0B6E1, IDI2_METTP ;  Q2RIU8, IDI2_MOOTA ;  A4TE63, IDI2_MYCGI ;
DR   B2HGA4, IDI2_MYCMM ;  A0PL81, IDI2_MYCUA ;  A1T741, IDI2_MYCVP ;
DR   Q3IUB0, IDI2_NATPD ;  Q5YXN4, IDI2_NOCFA ;  Q8YNH4, IDI2_NOSS1 ;
DR   Q8EST0, IDI2_OCEIH ;  Q8L1I4, IDI2_PARZE ;  Q3B213, IDI2_PELLD ;
DR   B4SCG2, IDI2_PELPB ;  Q7N0A6, IDI2_PHOLL ;  Q6L1S1, IDI2_PICTO ;
DR   A4SGE6, IDI2_PROVI ;  A4VR98, IDI2_PSEU5 ;  Q9UZS9, IDI2_PYRAB ;
DR   Q8ZYF6, IDI2_PYRAE ;  A4WH01, IDI2_PYRAR ;  Q8U2H9, IDI2_PYRFU ;
DR   O58893, IDI2_PYRHO ;  A1RTI3, IDI2_PYRIL ;  Q76CZ1, IDI2_PYRKO ;
DR   Q989L5, IDI2_RHILO ;  C3PNP9, IDI2_RICAE ;  A8GNY6, IDI2_RICAH ;
DR   A8GWR2, IDI2_RICB8 ;  Q1RIK2, IDI2_RICBR ;  A8EYM2, IDI2_RICCK ;
DR   Q92HM7, IDI2_RICCN ;  Q4ULD7, IDI2_RICFE ;  Q9ZD90, IDI2_RICPR ;
DR   C4K1D6, IDI2_RICPU ;  B0BXY6, IDI2_RICRO ;  A8GSH4, IDI2_RICRS ;
DR   Q68WS6, IDI2_RICTY ;  A7X5W0, IDI2_STAA1 ;  A6U473, IDI2_STAA2 ;
DR   Q2FEF1, IDI2_STAA3 ;  Q2FVR9, IDI2_STAA8 ;  A5IVC7, IDI2_STAA9 ;
DR   Q2YYY9, IDI2_STAAB ;  Q5HDL0, IDI2_STAAC ;  A6QJI7, IDI2_STAAE ;
DR   P65102, IDI2_STAAM ;  P99172, IDI2_STAAN ;  Q6GE88, IDI2_STAAR ;
DR   Q6G6X4, IDI2_STAAS ;  A8Z536, IDI2_STAAT ;  P58052, IDI2_STAAU ;
DR   Q8NV55, IDI2_STAAW ;  Q5HLP8, IDI2_STAEQ ;  Q8CRB6, IDI2_STAES ;
DR   Q4L8K4, IDI2_STAHJ ;  Q49ZS3, IDI2_STAS1 ;  Q9KWG2, IDI2_STRC1 ;
DR   A8AUV1, IDI2_STRGC ;  Q8DUI9, IDI2_STRMU ;  P65103, IDI2_STRP1 ;
DR   Q04M86, IDI2_STRP2 ;  P0DB80, IDI2_STRP3 ;  Q5XCM6, IDI2_STRP6 ;
DR   C1C5C3, IDI2_STRP7 ;  P65105, IDI2_STRP8 ;  B8ZLF5, IDI2_STRPJ ;
DR   Q48U28, IDI2_STRPM ;  Q97SH8, IDI2_STRPN ;  P0DB81, IDI2_STRPQ ;
DR   B2ILS5, IDI2_STRPS ;  Q8DR48, IDI2_STRR6 ;  C3N063, IDI2_SULIA ;
DR   C4KJA2, IDI2_SULIK ;  C3MJQ6, IDI2_SULIL ;  C3MZ14, IDI2_SULIM ;
DR   C3NMP1, IDI2_SULIN ;  C3N8S7, IDI2_SULIY ;  P61615, IDI2_SULSH ;
DR   P95997, IDI2_SULSO ;  Q96YW9, IDI2_SULTO ;  Q67NT4, IDI2_SYMTH ;
DR   Q5N019, IDI2_SYNP6 ;  P74287, IDI2_SYNY3 ;  Q9HLX2, IDI2_THEAC ;
DR   Q8DJ26, IDI2_THEEB ;  B1YA32, IDI2_THENV ;  B6YST3, IDI2_THEON ;
DR   C6A3U0, IDI2_THESM ;  Q97CC2, IDI2_THEVO ;  Q31EW3, IDI2_THICR ;
DR   A7N787, IDI2_VIBHB ;  Q87JH5, IDI2_VIBPA ;  A7IMW3, IDI2_XANP2 ;
DR   Q8KP37, IDI_AGRME  ;  Q9KWD1, IDI_AGRRH  ;  A1R1M6, IDI_ARTAT  ;
DR   Q9KK75, IDI_BRELN  ;  A9AST0, IDI_BURM1  ;  Q7X5H2, IDI_CITFR  ;
DR   A8AP95, IDI_CITK8  ;  A5CV36, IDI_CLAM3  ;  B0RIB7, IDI_CLAMS  ;
DR   P60923, IDI_CORDI  ;  Q8FND7, IDI_COREF  ;  A4QG13, IDI_CORGB  ;
DR   Q8NN99, IDI_CORGL  ;  Q9NH02, IDI_DICDI  ;  A8LQ20, IDI_DINSH  ;
DR   A7ZQZ8, IDI_ECO24  ;  B7UHT8, IDI_ECO27  ;  B7MM76, IDI_ECO45  ;
DR   Q8XD58, IDI_ECO57  ;  B5YQ81, IDI_ECO5E  ;  B7NW30, IDI_ECO7I  ;
DR   B7MZ42, IDI_ECO81  ;  B7LYF3, IDI_ECO8A  ;  C5A0G1, IDI_ECOBW  ;
DR   B1XEH6, IDI_ECODH  ;  A8A430, IDI_ECOHS  ;  A1AF79, IDI_ECOK1  ;
DR   Q0TDW3, IDI_ECOL5  ;  Q8FE75, IDI_ECOL6  ;  B1ITB3, IDI_ECOLC  ;
DR   Q46822, IDI_ECOLI  ;  B7N7D3, IDI_ECOLU  ;  B6I722, IDI_ECOSE  ;
DR   B1LR71, IDI_ECOSM  ;  Q1R7E2, IDI_ECOUT  ;  A4WE41, IDI_ENT38  ;
DR   Q6D3F5, IDI_ERWCT  ;  Q0RBQ7, IDI_FRAAA  ;  A1WXH5, IDI_HALHL  ;
DR   Q5UX45, IDI_HALMA  ;  Q9HP40, IDI_HALSA  ;  Q28W27, IDI_JANSC  ;
DR   B5XUF5, IDI_KLEP3  ;  A6TDP3, IDI_KLEP7  ;  B2GFH1, IDI_KOCRD  ;
DR   Q6AC73, IDI_LEIXX  ;  Q7VEU0, IDI_MYCBO  ;  A1KJG2, IDI_MYCBP  ;
DR   C1AP18, IDI_MYCBT  ;  A5U3A5, IDI_MYCTA  ;  P72002, IDI_MYCTU  ;
DR   A1T5G2, IDI_MYCVP  ;  Q5YYB6, IDI_NOCFA  ;  Q6LUX5, IDI_PHOPR  ;
DR   Q6A5Z1, IDI_PROAC  ;  P26173, IDI_RHOCB  ;  A3PL07, IDI_RHOS1  ;
DR   Q9Z5D3, IDI_RHOS4  ;  A4WRA6, IDI_RHOS5  ;  B9KK15, IDI_RHOSK  ;
DR   Q16DR2, IDI_ROSDO  ;  A4FK76, IDI_SACEN  ;  B5F5G3, IDI_SALA4  ;
DR   A9MRI5, IDI_SALAR  ;  Q57K77, IDI_SALCH  ;  B5FUF2, IDI_SALDC  ;
DR   B5QXG6, IDI_SALEP  ;  B5RE00, IDI_SALG2  ;  B4TGV9, IDI_SALHS  ;
DR   B4T534, IDI_SALNS  ;  Q5PL31, IDI_SALPA  ;  A9N3L5, IDI_SALPB  ;
DR   C0PY11, IDI_SALPC  ;  B5BFK4, IDI_SALPK  ;  B4TUQ7, IDI_SALSV  ;
DR   Q8Z3X9, IDI_SALTI  ;  Q8ZM82, IDI_SALTY  ;  A8GDW2, IDI_SERP5  ;
DR   B2U0Q6, IDI_SHIB3  ;  Q31WF1, IDI_SHIBS  ;  Q32BV2, IDI_SHIDS  ;
DR   Q0T107, IDI_SHIF8  ;  Q83MJ9, IDI_SHIFL  ;  Q3YXY0, IDI_SHISS  ;
DR   Q5LWT6, IDI_SILPO  ;  Q82MJ7, IDI_STRAW  ;  Q9X7Q6, IDI_STRCO  ;
DR   B1VTW2, IDI_STRGG  ;  Q5E7U8, IDI_VIBF1  ;  B5F9P6, IDI_VIBFM  ;
//
ID   5.3.3.3
DE   Vinylacetyl-CoA Delta-isomerase.
AN   Vinylacetyl coenzyme A isomerase.
CA   Vinylacetyl-CoA = (E)-but-2-enoyl-CoA.
CC   -!- Also acts on 3-methyl-vinylacetyl-CoA.
DR   P55792, HDVD_CLOAM ;
//
ID   5.3.3.4
DE   Muconolactone Delta-isomerase.
AN   Muconolactone isomerase.
CA   (S)-5-oxo-2,5-dihydrofuran-2-acetate = 5-oxo-4,5-dihydrofuran-2-acetate.
CC   -!- Formerly EC 3.1.1.16.
DR   O33947, CATC1_ACILW;  O33951, CATC2_ACILW;  Q43932, CATC_ACIAD ;
DR   P80573, CATC_CUPPJ ;  Q9I0X4, CATC_PSEAE ;  P00948, CATC_PSEPU ;
DR   P95609, CATC_RHOOP ;
//
ID   5.3.3.5
DE   Cholestenol Delta-isomerase.
CA   5-alpha-cholest-7-en-3-beta-ol = 5-alpha-cholest-8-en-3-beta-ol.
DR   O48962, EBP_ARATH  ;  Q60490, EBP_CAVPO  ;  Q55E32, EBP_DICDI  ;
DR   Q15125, EBP_HUMAN  ;  P70245, EBP_MOUSE  ;  Q9FTZ2, EBP_ORYSJ  ;
DR   Q9JJ46, EBP_RAT    ;
//
ID   5.3.3.6
DE   Methylitaconate Delta-isomerase.
CA   Methylitaconate = 2,3-dimethylmaleate.
CC   -!- Forms part of the nicotinate-fermentation catabolism pathway in
CC       Eubacterium barkeri.
CC   -!- Other enzymes involved in this pathway are EC 1.17.1.5, EC 1.3.7.1,
CC       EC 3.5.2.18, EC 1.1.1.291, EC 5.4.99.4, EC 4.2.1.85 and EC 4.1.3.32.
DR   Q0QLE6, MII_EUBBA  ;
//
ID   5.3.3.7
DE   Aconitate Delta-isomerase.
AN   Aconitate isomerase.
CA   Trans-aconitate = cis-aconitate.
CC   -!- Cis-aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3-
CC       tricarboxylate.
CC   -!- This isomerization could take place either in a direct cis-trans
CC       interconversion or by an allelic rearrangement; the enzyme has been
CC       shown to catalyze the latter change.
//
ID   5.3.3.8
DE   Dodecenoyl-CoA isomerase.
AN   3,2-trans-enoyl-CoA isomerase.
AN   Acetylene-allene isomerase.
AN   Delta(3),Delta(2)-enoyl-CoA isomerase.
AN   Delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase.
AN   Dodecenoyl-CoA Delta-isomerase.
CA   (3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl-CoA.
CC   -!- Also catalyzes the interconversion of 3-acetylenic fatty acyl
CC       thioesters and (+)-2,3-dienoyl fatty acyl thioesters, with fatty acid
CC       chain lengths C(6) to C(12).
DR   Q9ZPI6, AIM1_ARATH ;  P55100, ECHP_CAVPO ;  Q6NYL3, ECHP_DANRE ;
DR   Q08426, ECHP_HUMAN ;  Q9DBM2, ECHP_MOUSE ;  Q5R5M8, ECHP_PONAB ;
DR   P07896, ECHP_RAT   ;  P42126, ECI1_HUMAN ;  P42125, ECI1_MOUSE ;
DR   P23965, ECI1_RAT   ;  Q05871, ECI1_YEAST ;  O75521, ECI2_HUMAN ;
DR   Q9WUR2, ECI2_MOUSE ;  Q5XIC0, ECI2_RAT   ;  Q4UL32, FAD3_RICFE ;
DR   Q9ZCZ1, FAD3_RICPR ;  Q68WH7, FAD3_RICTY ;  Q6FF68, FADB_ACIAD ;
DR   B7H1I0, FADB_ACIB3 ;  B7I3P1, FADB_ACIB5 ;  B2I2J9, FADB_ACIBC ;
DR   B0VLX4, FADB_ACIBS ;  B0VE45, FADB_ACIBY ;  A0KEL1, FADB_AERHH ;
DR   A4STF2, FADB_AERS4 ;  B6EGU2, FADB_ALISL ;  A8ACZ4, FADB_CITK8 ;
DR   Q489W3, FADB_COLP3 ;  A7ZU51, FADB_ECO24 ;  B7UNH4, FADB_ECO27 ;
DR   B7MHD1, FADB_ECO45 ;  B7L9A7, FADB_ECO55 ;  Q8X8I2, FADB_ECO57 ;
DR   B5YY93, FADB_ECO5E ;  B7NV20, FADB_ECO7I ;  B7N2F2, FADB_ECO81 ;
DR   B7M649, FADB_ECO8A ;  C5A020, FADB_ECOBW ;  B1XAK8, FADB_ECODH ;
DR   A8A6V1, FADB_ECOHS ;  Q0TAL0, FADB_ECOL5 ;  Q8FBI2, FADB_ECOL6 ;
DR   B1IW61, FADB_ECOLC ;  P21177, FADB_ECOLI ;  B7NFE7, FADB_ECOLU ;
DR   B6I4I6, FADB_ECOSE ;  B1LM32, FADB_ECOSM ;  Q1R466, FADB_ECOUT ;
DR   A4WFX4, FADB_ENT38 ;  Q9F0Y7, FADB_ENTCL ;  A7MQP0, FADB_ENTS8 ;
DR   Q6DAP5, FADB_ERWCT ;  B7LTY9, FADB_ESCF3 ;  Q5QXH7, FADB_IDILO ;
DR   B5XYH0, FADB_KLEP3 ;  A6TGM4, FADB_KLEP7 ;  Q7MZ92, FADB_PHOLL ;
DR   Q6LW06, FADB_PHOPR ;  Q48GW3, FADB_PSE14 ;  A6V382, FADB_PSEA7 ;
DR   B7UYR6, FADB_PSEA8 ;  Q02PH8, FADB_PSEAB ;  Q9HZJ2, FADB_PSEAE ;
DR   Q1I7D4, FADB_PSEE4 ;  Q4KFC4, FADB_PSEF5 ;  P28793, FADB_PSEFR ;
DR   C3K613, FADB_PSEFS ;  A4XSM8, FADB_PSEMY ;  Q93Q12, FADB_PSEOL ;
DR   A5W6H0, FADB_PSEP1 ;  Q3K9D8, FADB_PSEPF ;  B0KH74, FADB_PSEPG ;
DR   Q88L02, FADB_PSEPK ;  Q9AHY3, FADB_PSEPU ;  B1J5A5, FADB_PSEPW ;
DR   Q87ZB2, FADB_PSESM ;  Q4ZRA0, FADB_PSEU2 ;  A4VKA3, FADB_PSEU5 ;
DR   Q4FQC6, FADB_PSYA2 ;  Q1Q8J9, FADB_PSYCK ;  A5WH99, FADB_PSYWF ;
DR   B5EZW0, FADB_SALA4 ;  Q57HM6, FADB_SALCH ;  B5QW85, FADB_SALEP ;
DR   B5RFL6, FADB_SALG2 ;  B4SZ85, FADB_SALNS ;  Q5PKQ2, FADB_SALPA ;
DR   A9MYB0, FADB_SALPB ;  B5BIZ0, FADB_SALPK ;  B4TNZ1, FADB_SALSV ;
DR   Q8Z3C6, FADB_SALTI ;  Q9L6L5, FADB_SALTY ;  A8G8D1, FADB_SERP5 ;
DR   A1S1I8, FADB_SHEAM ;  B8E3R3, FADB_SHEB2 ;  A3CYJ4, FADB_SHEB5 ;
DR   A6WHA0, FADB_SHEB8 ;  A9KU91, FADB_SHEB9 ;  Q08A39, FADB_SHEFN ;
DR   B0TLB9, FADB_SHEHH ;  A3Q8U4, FADB_SHELP ;  Q8EKR9, FADB_SHEON ;
DR   A8GYG0, FADB_SHEPA ;  A4Y1B6, FADB_SHEPC ;  B8CH91, FADB_SHEPW ;
DR   A0KR50, FADB_SHESA ;  A8FP63, FADB_SHESH ;  Q0HPB7, FADB_SHESM ;
DR   Q0I0T3, FADB_SHESR ;  A1RDW6, FADB_SHESW ;  B1KCZ3, FADB_SHEWM ;
DR   B2TVJ5, FADB_SHIB3 ;  Q32A21, FADB_SHIDS ;  Q0SZ36, FADB_SHIF8 ;
DR   Q83PG1, FADB_SHIFL ;  Q3YVC1, FADB_SHISS ;  A5F465, FADB_VIBC3 ;
DR   Q9KNI1, FADB_VIBCH ;  C3LSI3, FADB_VIBCM ;  Q5E8X6, FADB_VIBF1 ;
DR   B5FEW8, FADB_VIBFM ;  A7N1D2, FADB_VIBHB ;  Q87TN9, FADB_VIBPA ;
DR   B7VGL4, FADB_VIBSL ;  Q8DDK6, FADB_VIBVU ;  Q7MQH9, FADB_VIBVY ;
DR   A1JIG4, FADB_YERE8 ;  A7FDF2, FADB_YERP3 ;  Q1C2C4, FADB_YERPA ;
DR   B2K0Z6, FADB_YERPB ;  Q8ZAN0, FADB_YERPE ;  A9R754, FADB_YERPG ;
DR   Q1CN99, FADB_YERPN ;  A4TR27, FADB_YERPP ;  Q66FR8, FADB_YERPS ;
DR   B1JP63, FADB_YERPY ;  Q9ZPI5, MFP2_ARATH ;  O49809, MFPA_BRANA ;
DR   Q39659, MFPA_CUCSA ;  Q8W1L6, MFP_ORYSJ  ;
//
ID   5.3.3.9
DE   Prostaglandin-A(1) Delta-isomerase.
AN   Prostaglandin A isomerase.
CA   (13E)-(15S)-15-hydroxy-9-oxoprosta-10,13-dienoate = (13E)-(15S)-15-
CA   hydroxy-9-oxoprosta-11,13-dienoate.
CC   -!- Interconverts prostaglandin A(1) and prostaglandin C(1).
//
ID   5.3.3.10
DE   5-carboxymethyl-2-hydroxymuconate Delta-isomerase.
AN   5-carboxymethyl-2-hydroxymuconic acid isomerase.
AN   CHM isomerase.
CA   5-carboxymethyl-2-hydroxymuconate = 5-carboxy-2-oxohept-3-enedioate.
DR   Q46978, HPAG_ECOLX ;  Q9RPU5, HPAG_SALDU ;  Q05354, HPCD_ECOLX ;
DR   P37352, HPCE_ECOLX ;
//
ID   5.3.3.11
DE   Isopiperitenone Delta-isomerase.
CA   Isopiperitenone = piperitenone.
CC   -!- Involved in the biosynthesis of menthol and related monoterpenes in
CC       peppermint (Mentha piperita) leaves.
//
ID   5.3.3.12
DE   L-dopachrome isomerase.
AN   DCF.
AN   DCT.
AN   Dopachrome conversion factor.
AN   Dopachrome Delta(7),Delta(2)-isomerase.
AN   Dopachrome Delta-isomerase.
AN   Dopachrome isomerase.
AN   Dopachrome keto-enol isomerase.
AN   Dopachrome oxidoreductase.
AN   Dopachrome rearranging enzyme.
AN   Dopachrome tautomerase.
AN   L-dopachrome-methyl ester tautomerase.
AN   TRP.
AN   Tyrosinase-related protein 2.
CA   L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.
CF   Zinc.
CC   -!- Stereospecific for L-dopachrome (5,6-dioxo-2,3-5,6-tetrahydroindole-
CC       2-carboxylate).
CC   -!- Dopachrome methyl ester is a substrate, but dopaminochrome (2,3-
CC       dihydroxyindolyl-5,6-quinone) is not (see also EC 4.1.1.84).
PR   PROSITE; PDOC00398;
DR   P91850, MIFH_BRUMA ;  P81530, MIFH_TRIMR ;  P81529, MIFH_TRISP ;
DR   P81748, MIFH_TRITR ;  O44786, MIFH_WUCBA ;  P80177, MIF_BOVIN  ;
DR   Q02960, MIF_CHICK  ;  P14174, MIF_HUMAN  ;  Q4R549, MIF_MACFA  ;
DR   Q6DN04, MIF_MACMU  ;  O55052, MIF_MERUN  ;  P34884, MIF_MOUSE  ;
DR   P80928, MIF_PIG    ;  P30904, MIF_RAT    ;  Q1ZZU7, MIF_SHEEP  ;
DR   Q76BK2, MIF_XENLA  ;  A9JSE7, MIF_XENTR  ;  Q95119, TYRP2_BOVIN;
DR   O93505, TYRP2_CHICK;  P40126, TYRP2_HUMAN;  P29812, TYRP2_MOUSE;
DR   Q4R1H1, TYRP2_PIG  ;
//
ID   5.3.3.13
DE   Polyenoic fatty acid isomerase.
AN   Eicosapentaenoate cis-Delta(5,8,11,14,17)-eicosapentaenoate cis-Delta(5)-
AN   trans-Delta(7,9)-cis-Delta(14,17) isomerase.
AN   PFI.
CA   (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate = (5Z,7E,9E,14Z,17Z)-
CA   icosapentaenoate.
CC   -!- The enzyme from the red alga Ptilota filicina catalyzes the
CC       isomerization of skip dienes (methylene-interrupted double bonds) in
CC       a broad range of fatty acids and fatty-acid analogs, such as
CC       arachidonate and gamma-linolenate, to yield a conjugated triene.
//
ID   5.3.3.14
DE   Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
AN   Beta-hydroxydecanoyl thioester dehydrase.
AN   Trans-2,cis-3-decenoyl-ACP isomerase.
AN   Trans-2-decenoyl-ACP isomerase.
CA   Trans-dec-2-enoyl-[acyl-carrier-protein] = cis-dec-3-enoyl-[acyl-carrier-
CA   protein].
CC   -!- While the enzyme from Escherichia coli is highly specific for the
CC       10-carbon enoyl-ACP, the enzyme from Streptococcus pneumoniae can
CC       also use the 12-carbon enoyl-ACP as substrate in vitro but not 14- or
CC       16-carbon enoyl-ACPs.
CC   -!- ACP can be replaced by either CoA or N-acetylcysteamine thioesters.
CC   -!- The cis-3-enoyl product is required to form unsaturated fatty acids,
CC       such as palmitoleic acid and cis-vaccenic acid, in dissociated (or
CC       type II) fatty-acid biosynthesis.
//
ID   5.3.3.15
DE   Ascopyrone tautomerase.
AN   1,5-anhydro-D-glycero-hex-3-en-2-ulose tautomerase.
AN   APM tautomerase.
AN   APTM.
AN   Ascopyrone intramolecular oxidoreductase.
AN   Ascopyrone isomerase.
AN   Ascopyrone P tautomerase.
CA   1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 1,5-anhydro-4-deoxy-D-
CA   glycero-hex-1-en-3-ulose.
CC   -!- Catalyzes one of the steps in the anhydrofructose pathway, which
CC       leads to the degradation of glycogen and starch via 1,5-anhydro-D-
CC       fructose.
CC   -!- The other enzymes involved in this pathway are EC 4.2.1.110,
CC       EC 4.2.1.111 and EC 4.2.2.13.
CC   -!- Ascopyrone P is an anti-oxidant.
//
ID   5.3.3.16
DE   4-oxalomesaconate tautomerase.
CA   (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate = 2-hydroxy-4-carboxyhexa-2,4-
CA   dienedioate.
CC   -!- This enzyme has been characterized from the bacterium Pseudomonas
CC       putida KT2440 and is involved in the degradation pathway of syringate
CC       and gallate.
CC   -!- It catalyzes the interconversion of two of the tautomers of
CC       4-oxalomesaconate, a reaction that can also occur spontaneously.
//
ID   5.3.4.1
DE   Protein disulfide-isomerase.
AN   S-S rearrangase.
CA   Catalyzes the rearrangement of -S-S- bonds in proteins.
CC   -!- Needs reducing agents or partly reduced enzyme; the reaction depends
CC       on sulfhydryl-disulfide interchange.
PR   PROSITE; PDOC00172;
DR   P40557, EPS1_YEAST ;  Q92249, ERP38_NEUCR;  P38658, ERP60_SCHMA;
DR   P32474, EUG1_YEAST ;  Q12404, MPD1_YEAST ;  Q99316, MPD2_YEAST ;
DR   Q9XI01, PDI11_ARATH;  Q53LQ0, PDI11_ORYSJ;  Q9SRG3, PDI12_ARATH;
DR   Q7XRB5, PDI12_ORYSJ;  Q8VX13, PDI13_ARATH;  Q9FF55, PDI14_ARATH;
DR   Q67IX6, PDI14_ORYSJ;  A3KPF5, PDI15_ARATH;  Q5WA72, PDI15_ORYSJ;
DR   Q66GQ3, PDI16_ARATH;  Q17967, PDI1_CAEEL ;  Q86IA3, PDI1_DICDI ;
DR   Q10057, PDI1_SCHPO ;  O22263, PDI21_ARATH;  Q75M08, PDI21_ORYSJ;
DR   Q9MAU6, PDI22_ARATH;  Q942L2, PDI22_ORYSJ;  O48773, PDI23_ARATH;
DR   Q67UF5, PDI23_ORYSJ;  Q17770, PDI2_CAEEL ;  Q54EN4, PDI2_DICDI ;
DR   O13811, PDI2_SCHPO ;  P05307, PDIA1_BOVIN;  P09102, PDIA1_CHICK;
DR   Q8R4U2, PDIA1_CRIGR;  P07237, PDIA1_HUMAN;  Q2HWU2, PDIA1_MACFU;
DR   P09103, PDIA1_MOUSE;  Q5R5B6, PDIA1_PONAB;  P21195, PDIA1_RABIT;
DR   P04785, PDIA1_RAT  ;  Q13087, PDIA2_HUMAN;  D3Z6P0, PDIA2_MOUSE;
DR   Q5RCH2, PDIA2_PONAB;  P38657, PDIA3_BOVIN;  Q8JG64, PDIA3_CHICK;
DR   Q4VIT4, PDIA3_CHLAE;  P30101, PDIA3_HUMAN;  P86235, PDIA3_MESAU;
DR   P27773, PDIA3_MOUSE;  P81246, PDIA3_PAPHA;  Q5RDG4, PDIA3_PONAB;
DR   P11598, PDIA3_RAT  ;  Q29RV1, PDIA4_BOVIN;  P34329, PDIA4_CAEEL;
DR   P13667, PDIA4_HUMAN;  P08003, PDIA4_MOUSE;  P38659, PDIA4_RAT  ;
DR   Q2KIL5, PDIA5_BOVIN;  Q14554, PDIA5_HUMAN;  Q921X9, PDIA5_MOUSE;
DR   Q5I0H9, PDIA5_RAT  ;  Q11067, PDIA6_CAEEL;  Q15084, PDIA6_HUMAN;
DR   P38661, PDIA6_MEDSA;  P38660, PDIA6_MESAU;  Q922R8, PDIA6_MOUSE;
DR   Q5R6T1, PDIA6_PONAB;  Q63081, PDIA6_RAT  ;  Q00002, PDI_ALTAL  ;
DR   Q12730, PDI_ASPNG  ;  Q00248, PDI_ASPOR  ;  Q9XF61, PDI_DATGL  ;
DR   P54399, PDI_DROME  ;  P80284, PDI_HORVU  ;  P55059, PDI_HUMIN  ;
DR   P52588, PDI_MAIZE  ;  P29828, PDI_MEDSA  ;  Q43116, PDI_RICCO  ;
DR   P52589, PDI_WHEAT  ;  P17967, PDI_YEAST  ;  Q69ST6, PID13_ORYSJ;
DR   Q00216, TIGA_ASPNG ;  Q96JJ7, TMX3_HUMAN ;  Q8BXZ1, TMX3_MOUSE ;
DR   Q5R875, TMX3_PONAB ;  Q6GNG3, TMX3_XENLA ;  Q869Z0, Y5025_DICDI;
//
ID   5.3.99.1
DE   Deleted entry.
//
ID   5.3.99.2
DE   Prostaglandin-D synthase.
AN   PGD2 synthase.
AN   PGH-PGD isomerase.
AN   Prostaglandin D synthetase.
AN   Prostaglandin D2 synthase.
AN   Prostaglandin endoperoxide Delta-isomerase.
AN   Prostaglandin-H(2) Delta-isomerase.
CA   (5Z,13E,15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate =
CA   (5Z,13E,15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate.
CF   Glutathione.
CC   -!- Brings about the opening of the epidioxy bridge.
PR   PROSITE; PDOC00187;
DR   O73888, HPGDS_CHICK;  O60760, HPGDS_HUMAN;  Q9JHF7, HPGDS_MOUSE;
DR   O35543, HPGDS_RAT  ;  O02853, PTGDS_BOVIN;  Q9XS65, PTGDS_CANFA;
DR   Q29487, PTGDS_FELCA;  Q8WNM1, PTGDS_GORGO;  O97921, PTGDS_HORSE;
DR   P41222, PTGDS_HUMAN;  Q9TUI1, PTGDS_MACFU;  O09114, PTGDS_MOUSE;
DR   Q29095, PTGDS_PIG  ;  Q8WNM0, PTGDS_PONPY;  P22057, PTGDS_RAT  ;
DR   Q9XSM0, PTGDS_SHEEP;  Q29562, PTGDS_URSAR;
//
ID   5.3.99.3
DE   Prostaglandin-E synthase.
AN   Endoperoxide isomerase.
AN   PGE isomerase.
AN   PGH-PGE isomerase.
AN   Prostaglandin-H(2) E-isomerase.
CA   (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate =
CA   (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate.
CF   Glutathione.
CC   -!- Brings about the opening of the epidioxy bridge.
DR   Q66LN0, PGES2_BOVIN;  Q7ZUC7, PGES2_DANRE;  Q9H7Z7, PGES2_HUMAN;
DR   Q9N0A4, PGES2_MACFA;  Q8BWM0, PGES2_MOUSE;  Q95L14, PTGES_BOVIN;
DR   A0SYQ0, PTGES_CANFA;  Q8HZJ2, PTGES_HORSE;  O14684, PTGES_HUMAN;
DR   Q6PWL6, PTGES_MACFA;  Q9JM51, PTGES_MOUSE;  Q3ZBF7, TEBP_BOVIN ;
DR   Q90955, TEBP_CHICK ;  Q15185, TEBP_HUMAN ;  Q6PWL5, TEBP_MACFA ;
DR   Q9R0Q7, TEBP_MOUSE ;  Q5NVM4, TEBP_PONAB ;  P83868, TEBP_RAT   ;
//
ID   5.3.99.4
DE   Prostaglandin-I synthase.
AN   PGI(2) synthase.
AN   PGI(2) synthetase.
AN   Prostacyclin synthase.
CA   (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate =
CA   (5Z,13E)-(15S)-6,9-alpha-epoxy-11-alpha,15-dihydroxyprosta-5,13-dienoate.
CF   Heme-thiolate.
CC   -!- Converts prostaglandin H(2) into prostaglandin I(2) (prostacyclin).
PR   PROSITE; PDOC00081;
DR   Q29626, PTGIS_BOVIN;  Q16647, PTGIS_HUMAN;  O35074, PTGIS_MOUSE;
DR   Q62969, PTGIS_RAT  ;
//
ID   5.3.99.5
DE   Thromboxane-A synthase.
AN   Thromboxane synthase.
AN   Thromboxane synthetase.
CA   (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate =
CA   (5Z,13E)-(15S)-9-alpha,11-alpha-epoxy-15-hydroxythromboxa-5,13-dienoate.
CF   Heme-thiolate.
CC   -!- Converts prostaglandin H(2) into thromboxane A(2).
PR   PROSITE; PDOC00081;
DR   Q2KIG5, THAS_BOVIN ;  P24557, THAS_HUMAN ;  Q2PG45, THAS_MACFA ;
DR   P36423, THAS_MOUSE ;  P47787, THAS_PIG   ;  P49430, THAS_RAT   ;
//
ID   5.3.99.6
DE   Allene-oxide cyclase.
CA   (9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate = (15Z)-12-oxophyto-
CA   10,15-dienoate.
CC   -!- Allene oxides formed by the action of EC 4.2.1.92 are converted into
CC       cyclopentenone derivatives.
DR   Q9LS03, AOC1_ARATH ;  Q9LS02, AOC2_ARATH ;  Q9LS01, AOC3_ARATH ;
DR   Q93ZC5, AOC4_ARATH ;
//
ID   5.3.99.7
DE   Styrene-oxide isomerase.
AN   SOI.
CA   Styrene oxide = phenylacetaldehyde.
CC   -!- Highly specific.
//
ID   5.3.99.8
DE   Capsanthin/capsorubin synthase.
AN   Capsanthin-capsorubin synthase.
AN   CCS.
AN   Ketoxanthophyll synthase.
CA   (1) Violaxanthin = capsorubin.
CA   (2) Antheraxanthin = capsanthin.
CC   -!- Induced during chromoplast differentiation in plants.
CC   -!- Isomerization of the epoxide ring of violaxanthin gives the
CC       cyclopentyl-ketone of capsorubin or capsanthin.
DR   Q42435, CCS_CAPAN  ;  Q9SEA0, CCS_CITSI  ;
//
ID   5.3.99.9
DE   Neoxanthin synthase.
AN   NSY.
CA   Violaxanthin = neoxanthin.
CC   -!- The opening of the epoxide ring of violaxanthin generates a chiral
CC       allene.
CC   -!- Neoxanthin is a precursor of the plant hormone abscisic acid and the
CC       last product of carotenoid synthesis in green plants.
DR   Q9M424, NXS_SOLTU  ;
//
ID   5.3.99.n1
DE   2-keto-myo-inositol isomerase.
AN   2KMI isomerase.
AN   Inosose isomerase.
CA   2,4,6/3,5-pentahydroxycyclohexanone = 2,3,5/4,6-
CA   pentahydroxycyclohexanone.
CF   Divalent cation.
CC   -!- Part of the myo-inositol/D-chiro-inositol degradation pathway leading
CC       to acetyl-CoA together with EC 1.1.1.n6, EC 4.2.1.44, EC 3.7.1.n2,
CC       EC 5.3.1.n1, EC 2.7.1.92 EC 4.1.2.29 and EC 1.2.1.18.
DR   A7ZAH3, IOLI_BACA2 ;  Q9KAH2, IOLI_BACHD ;  Q65D08, IOLI_BACLD ;
DR   P42419, IOLI_BACSU ;
//
ID   5.4.1.1
DE   Lysolecithin acylmutase.
AN   Lysolecithin migratase.
CA   2-lysolecithin = 3-lysolecithin.
//
ID   5.4.1.2
DE   Precorrin-8X methylmutase.
AN   HBA synthase.
AN   Hydrogenobyrinic acid-binding protein.
AN   Precorrin isomerase.
CA   Precorrin-8X = hydrogenobyrinate.
DR   P63840, COBH_MYCBO ;  P63839, COBH_MYCTU ;  Q9HZU2, COBH_PSEAE ;
DR   P21638, COBH_PSEDE ;
//
ID   5.4.2.1
DE   Phosphoglycerate mutase.
AN   PGAM.
AN   Phosphoglycerate phosphomutase.
AN   Phosphoglyceromutase.
CA   2-phospho-D-glycerate = 3-phospho-D-glycerate.
CC   -!- The enzymes from mammals and from Saccharomyces cerevisiae are
CC       phosphorylated by (2R)-2,3-diphosphoglycerate, which is also an
CC       intermediate.
CC   -!- With the rabbit muscle enzyme, dissociation of bisphosphate from the
CC       enzyme is much slower that the overall isomerization.
CC   -!- Also catalyze, slowly, the reactions of EC 5.4.2.4.
CC   -!- Enzymes from wheat, rice, insects and some fungi, however, have
CC       maximum activity in the absence of 2,3-diphosphophosphoglycerate,
CC       and were formerly listed under the present number as phosphoglycerate
CC       phosphomutase.
CC   -!- Formerly EC 2.7.5.3.
PR   PROSITE; PDOC00158;
DR   O28523, APGM1_ARCFU;  Q59007, APGM1_METJA;  O27628, APGM1_METTH;
DR   O28847, APGM2_ARCFU;  Q60326, APGM2_METJA;  O26518, APGM2_METTH;
DR   Q9YBI2, APGM_AERPE ;  O66820, APGM_AQUAE ;  Q1IW58, APGM_DEIGD ;
DR   Q9RSA0, APGM_DEIRA ;  Q74C57, APGM_GEOSL ;  A8AC98, APGM_IGNH4 ;
DR   A6UTF2, APGM_META3 ;  P58812, APGM_METAC ;  Q46E58, APGM_METBF ;
DR   Q12UL5, APGM_METBU ;  P58813, APGM_METKA ;  A2SR62, APGM_METLZ ;
DR   A4FW85, APGM_METM5 ;  A9A9M4, APGM_METM6 ;  A6VH25, APGM_METM7 ;
DR   Q8PX04, APGM_METMA ;  A3CSK8, APGM_METMJ ;  Q6LXB3, APGM_METMP ;
DR   B8GFN7, APGM_METPE ;  A5UKY4, APGM_METS3 ;  A4YIX4, APGM_METS5 ;
DR   Q2NES7, APGM_METST ;  A0B6L2, APGM_METTP ;  A6UQ84, APGM_METVS ;
DR   Q6KZJ6, APGM_PICTO ;  Q9V2M6, APGM_PYRAB ;  Q8ZVE4, APGM_PYRAE ;
DR   A4WL27, APGM_PYRAR ;  A3MWR8, APGM_PYRCJ ;  P58814, APGM_PYRFU ;
DR   O57742, APGM_PYRHO ;  A1RTD5, APGM_PYRIL ;  Q5JI21, APGM_PYRKO ;
DR   Q4JAH5, APGM_SULAC ;  C3MZ46, APGM_SULIA ;  C4KIC4, APGM_SULIK ;
DR   C3MQZ8, APGM_SULIL ;  C3MWY6, APGM_SULIM ;  C3NGG9, APGM_SULIN ;
DR   C3N766, APGM_SULIY ;  Q980A0, APGM_SULSO ;  Q975P3, APGM_SULTO ;
DR   B7IDT4, APGM_THEAB ;  Q9HL27, APGM_THEAC ;  C5A4S1, APGM_THEGJ ;
DR   A6LMV5, APGM_THEM4 ;  Q9X295, APGM_THEMA ;  B9K857, APGM_THENN ;
DR   B1Y9H0, APGM_THENV ;  A5ILK6, APGM_THEP1 ;  B1LAP9, APGM_THESQ ;
DR   Q72GG0, APGM_THET2 ;  Q5SM27, APGM_THET8 ;  Q979H8, APGM_THEVO ;
DR   Q99288, DET1_YEAST ;  Q737X5, GPMA1_BACC1;  Q8A8R2, GPMA1_BACTN;
DR   Q7NK82, GPMA1_GLOVI;  Q74LL9, GPMA1_LACJO;  Q88YY8, GPMA1_LACPL;
DR   Q38ZH8, GPMA1_LACSS;  Q82XS4, GPMA1_NITEU;  Q2YBZ1, GPMA1_NITMU;
DR   Q732Z5, GPMA2_BACC1;  Q8A765, GPMA2_BACTN;  Q7NJF7, GPMA2_GLOVI;
DR   Q74L45, GPMA2_LACJO;  Q88T35, GPMA2_LACPL;  Q38Z74, GPMA2_LACSS;
DR   Q82TU0, GPMA2_NITEU;  Q2Y9Z7, GPMA2_NITMU;  A1TTW5, GPMA_ACIAC ;
DR   B9MEZ2, GPMA_ACIET ;  A1WBJ3, GPMA_ACISJ ;  A3N0J2, GPMA_ACTP2 ;
DR   B3H1G9, GPMA_ACTP7 ;  B0BPB3, GPMA_ACTPJ ;  A6VLV0, GPMA_ACTSZ ;
DR   B9J6R3, GPMA_AGRRK ;  B9JYQ2, GPMA_AGRVS ;  Q0A915, GPMA_ALHEH ;
DR   B4RZM6, GPMA_ALTMD ;  Q5P7N4, GPMA_AROAE ;  B8HCQ9, GPMA_ARTCA ;
DR   A0JSU9, GPMA_ARTS2 ;  A8IGZ9, GPMA_AZOC5 ;  A1K9B9, GPMA_AZOSB ;
DR   C3PAW8, GPMA_BACAA ;  C3LIE5, GPMA_BACAC ;  A0RE96, GPMA_BACAH ;
DR   Q6KSL4, GPMA_BACAN ;  B7JPK2, GPMA_BACC0 ;  B7IX37, GPMA_BACC2 ;
DR   C1EUQ5, GPMA_BACC3 ;  B7H7P4, GPMA_BACC4 ;  B7HS46, GPMA_BACC7 ;
DR   A7GPN5, GPMA_BACCN ;  B9J102, GPMA_BACCQ ;  Q81DD2, GPMA_BACCR ;
DR   Q63B92, GPMA_BACCZ ;  Q5LAT7, GPMA_BACFN ;  Q64R85, GPMA_BACFR ;
DR   Q6HIL9, GPMA_BACHK ;  A9VFW9, GPMA_BACWK ;  A1UTM4, GPMA_BARBK ;
DR   Q8L1Z7, GPMA_BARHE ;  Q6FZ12, GPMA_BARQU ;  A9IXE7, GPMA_BART1 ;
DR   Q1LTL3, GPMA_BAUCH ;  Q6MJP3, GPMA_BDEBA ;  B2IEV6, GPMA_BEII9 ;
DR   B3DQI6, GPMA_BIFLD ;  P59159, GPMA_BIFLO ;  B7GUR7, GPMA_BIFLS ;
DR   Q7VR80, GPMA_BLOFL ;  Q492W5, GPMA_BLOPB ;  Q2L0A6, GPMA_BORA1 ;
DR   Q0SMJ5, GPMA_BORAP ;  Q7WQN2, GPMA_BORBR ;  O51602, GPMA_BORBU ;
DR   B7J2L3, GPMA_BORBZ ;  B5RMK4, GPMA_BORDL ;  Q660L2, GPMA_BORGA ;
DR   B2S101, GPMA_BORHD ;  Q7W1Q6, GPMA_BORPA ;  A9IFJ0, GPMA_BORPD ;
DR   Q7VS43, GPMA_BORPE ;  B5RQ00, GPMA_BORRA ;  A1R083, GPMA_BORT9 ;
DR   C0QV47, GPMA_BRAHW ;  Q89WK1, GPMA_BRAJA ;  A5E8K1, GPMA_BRASB ;
DR   A4YJP8, GPMA_BRASO ;  B2SC37, GPMA_BRUA1 ;  Q2YJN6, GPMA_BRUA2 ;
DR   Q576R3, GPMA_BRUAB ;  A9MCX8, GPMA_BRUC2 ;  C0RMJ1, GPMA_BRUMB ;
DR   Q8YDC9, GPMA_BRUME ;  A5VVV5, GPMA_BRUO2 ;  A9WW62, GPMA_BRUSI ;
DR   P59160, GPMA_BRUSU ;  B8D995, GPMA_BUCA5 ;  P57390, GPMA_BUCAI ;
DR   Q8K9N1, GPMA_BUCAP ;  B8D7J7, GPMA_BUCAT ;  Q89AJ4, GPMA_BUCBP ;
DR   Q057P1, GPMA_BUCCC ;  B1YNA6, GPMA_BURA4 ;  B1JZ61, GPMA_BURCC ;
DR   B4EA64, GPMA_BURCJ ;  Q0BBK5, GPMA_BURCM ;  A3MQ23, GPMA_BURM7 ;
DR   A2S625, GPMA_BURM9 ;  Q62F43, GPMA_BURMA ;  A1UZX9, GPMA_BURMS ;
DR   A3NR09, GPMA_BURP0 ;  Q3JWH7, GPMA_BURP1 ;  A3N5B0, GPMA_BURP6 ;
DR   B2JC95, GPMA_BURP8 ;  B2SX15, GPMA_BURPP ;  Q63XU7, GPMA_BURPS ;
DR   Q39CN6, GPMA_BURS3 ;  Q2T1H5, GPMA_BURTA ;  A4JI45, GPMA_BURVG ;
DR   B8GYN6, GPMA_CAUCN ;  Q9A634, GPMA_CAUCR ;  B0SY17, GPMA_CAUSK ;
DR   Q5L4Y3, GPMA_CHLAB ;  Q3AU60, GPMA_CHLCH ;  Q821N6, GPMA_CHLCV ;
DR   Q256A6, GPMA_CHLFF ;  B3EFK8, GPMA_CHLL2 ;  Q9PLK4, GPMA_CHLMU ;
DR   B3QPN8, GPMA_CHLP8 ;  B3EN99, GPMA_CHLPB ;  A1BE55, GPMA_CHLPD ;
DR   Q9Z743, GPMA_CHLPN ;  B0B8U8, GPMA_CHLT2 ;  B3QVL0, GPMA_CHLT3 ;
DR   Q3KKX2, GPMA_CHLTA ;  B0BAH7, GPMA_CHLTB ;  Q8KFC8, GPMA_CHLTE ;
DR   O84727, GPMA_CHLTR ;  A8AJ40, GPMA_CITK8 ;  A5CTZ0, GPMA_CLAM3 ;
DR   B0RAW4, GPMA_CLAMS ;  Q97FJ6, GPMA_CLOAB ;  A6LUA1, GPMA_CLOB8 ;
DR   A9KN01, GPMA_CLOPH ;  B5Y7Q7, GPMA_COPPD ;  Q6NJL2, GPMA_CORDI ;
DR   Q8FSH0, GPMA_COREF ;  A4QB41, GPMA_CORGB ;  Q8NTA5, GPMA_CORGL ;
DR   Q4JSW4, GPMA_CORJK ;  C4LLD4, GPMA_CORK4 ;  Q0KET8, GPMA_CUPNH ;
DR   Q476J7, GPMA_CUPPJ ;  B2AGP7, GPMA_CUPTR ;  B7KIT8, GPMA_CYAP7 ;
DR   Q11SV1, GPMA_CYTH3 ;  A9BUZ3, GPMA_DELAS ;  Q30WZ8, GPMA_DESDG ;
DR   C4XIQ5, GPMA_DESMR ;  Q727C0, GPMA_DESVH ;  B8DLN4, GPMA_DESVM ;
DR   A1VAI9, GPMA_DESVV ;  A5EV29, GPMA_DICNV ;  A7ZJD0, GPMA_ECO24 ;
DR   B7ULM8, GPMA_ECO27 ;  B7MGL2, GPMA_ECO45 ;  B7LAF6, GPMA_ECO55 ;
DR   P62709, GPMA_ECO57 ;  B5YRF2, GPMA_ECO5E ;  B7NNH7, GPMA_ECO7I ;
DR   B7MPN9, GPMA_ECO81 ;  B7M6B8, GPMA_ECO8A ;  C4ZXS6, GPMA_ECOBW ;
DR   B1X786, GPMA_ECODH ;  A7ZY11, GPMA_ECOHS ;  A1A8Z8, GPMA_ECOK1 ;
DR   Q0TJU6, GPMA_ECOL5 ;  P62708, GPMA_ECOL6 ;  B1IXY1, GPMA_ECOLC ;
DR   P62707, GPMA_ECOLI ;  B7N9Z7, GPMA_ECOLU ;  B6I7Q9, GPMA_ECOSE ;
DR   B1LM46, GPMA_ECOSM ;  C5BEL3, GPMA_EDWI9 ;  B2KBU4, GPMA_ELUMP ;
DR   A4W897, GPMA_ENT38 ;  Q839H4, GPMA_ENTFA ;  A7MIX7, GPMA_ENTS8 ;
DR   Q6D7E3, GPMA_ERWCT ;  B2VBS6, GPMA_ERWT9 ;  Q2N682, GPMA_ERYLH ;
DR   B7LK04, GPMA_ESCF3 ;  Q0RS35, GPMA_FRAAA ;  Q8RFG9, GPMA_FUSNN ;
DR   B5EC38, GPMA_GEOBB ;  Q39V40, GPMA_GEOMG ;  Q74CR0, GPMA_GEOSL ;
DR   C6E639, GPMA_GEOSM ;  Q7VL28, GPMA_HAEDU ;  Q4QME2, GPMA_HAEI8 ;
DR   A5UDW8, GPMA_HAEIE ;  A5UHR1, GPMA_HAEIG ;  P44865, GPMA_HAEIN ;
DR   B8F5J4, GPMA_HAEPS ;  Q0I4D8, GPMA_HAES1 ;  B0US27, GPMA_HAES2 ;
DR   A1WWH7, GPMA_HALHL ;  C4K389, GPMA_HAMD5 ;  B4U616, GPMA_HYDS0 ;
DR   Q0C678, GPMA_HYPNA ;  B5XZB2, GPMA_KLEP3 ;  A6T6I3, GPMA_KLEP7 ;
DR   Q5FMJ3, GPMA_LACAC ;  Q9CIM0, GPMA_LACLA ;  A2RI67, GPMA_LACLM ;
DR   Q031Y3, GPMA_LACLS ;  Q6ADH3, GPMA_LEIXX ;  B1Y3R5, GPMA_LEPCP ;
DR   Q929G8, GPMA_LISIN ;  C1KXG0, GPMA_LISMC ;  Q71XG0, GPMA_LISMF ;
DR   B8DFA5, GPMA_LISMH ;  Q8Y571, GPMA_LISMO ;  A0AKV8, GPMA_LISW6 ;
DR   Q65Q32, GPMA_MANSM ;  Q0ALQ9, GPMA_MARMM ;  Q11CB5, GPMA_MESSB ;
DR   Q8TN93, GPMA_METAC ;  A7I8A7, GPMA_METB6 ;  B7KNX9, GPMA_METC4 ;
DR   A9W5P5, GPMA_METEP ;  Q2FTH0, GPMA_METHJ ;  B3DZZ7, GPMA_METI4 ;
DR   Q8PST3, GPMA_METMA ;  B1ZA86, GPMA_METPB ;  B8GFF8, GPMA_METPE ;
DR   A2SDN6, GPMA_METPP ;  B1M6A7, GPMA_METRJ ;  B0UBD4, GPMA_METS4 ;
DR   B8EML2, GPMA_METSB ;  A6US15, GPMA_METVS ;  A0QLK3, GPMA_MYCA1 ;
DR   P0A5R7, GPMA_MYCBO ;  A1KFW3, GPMA_MYCBP ;  C1AKG7, GPMA_MYCBT ;
DR   B8ZT86, GPMA_MYCLB ;  P53531, GPMA_MYCLE ;  B2HQV4, GPMA_MYCMM ;
DR   Q73SU2, GPMA_MYCPA ;  A5TZL7, GPMA_MYCTA ;  P0A5R6, GPMA_MYCTU ;
DR   A0PVZ3, GPMA_MYCUA ;  B9L9H5, GPMA_NAUPA ;  Q5F7C0, GPMA_NEIG1 ;
DR   B4RIY7, GPMA_NEIG2 ;  A9M1A2, GPMA_NEIM0 ;  Q9JTF2, GPMA_NEIMA ;
DR   Q9JYF7, GPMA_NEIMB ;  A1KV25, GPMA_NEIMF ;  Q1QRT7, GPMA_NITHX ;
DR   Q3JBA8, GPMA_NITOC ;  Q3SW71, GPMA_NITWN ;  Q5YP50, GPMA_NOCFA ;
DR   A1SP05, GPMA_NOCSJ ;  Q2G373, GPMA_NOVAD ;  A6WYJ2, GPMA_OCHA4 ;
DR   B6JCI9, GPMA_OLICO ;  A6L9K8, GPMA_PARD8 ;  A7HZ35, GPMA_PARL1 ;
DR   Q6MEW4, GPMA_PARUW ;  Q9CKU9, GPMA_PASMU ;  C6DCF6, GPMA_PECCP ;
DR   Q3B5J2, GPMA_PELLD ;  B4SEI0, GPMA_PELPB ;  Q4FP74, GPMA_PELUB ;
DR   Q7N6S0, GPMA_PHOLL ;  A1VKR6, GPMA_POLNA ;  B1XS92, GPMA_POLNS ;
DR   A4T096, GPMA_POLSQ ;  B2RHB7, GPMA_PORG3 ;  Q7MXP1, GPMA_PORGI ;
DR   B4S616, GPMA_PROA2 ;  Q6AAU8, GPMA_PROAC ;  B4EST0, GPMA_PROMH ;
DR   A4SDM0, GPMA_PROVI ;  Q15SN0, GPMA_PSEA6 ;  Q8Y2I3, GPMA_RALSO ;
DR   B3PXK3, GPMA_RHIE6 ;  Q8KL44, GPMA_RHIEC ;  Q1MMY4, GPMA_RHIL3 ;
DR   Q98DM0, GPMA_RHILO ;  B5ZWT2, GPMA_RHILW ;  Q92T25, GPMA_RHIME ;
DR   C3MBY8, GPMA_RHISN ;  B6IYD3, GPMA_RHOCS ;  Q21YW0, GPMA_RHOFD ;
DR   C1AZ61, GPMA_RHOOB ;  Q07UT3, GPMA_RHOP5 ;  Q21CH5, GPMA_RHOPB ;
DR   Q0SF09, GPMA_RHOSR ;  B5F050, GPMA_SALA4 ;  Q57RI5, GPMA_SALCH ;
DR   B5FP39, GPMA_SALDC ;  B5QX43, GPMA_SALEP ;  B5R739, GPMA_SALG2 ;
DR   B4TC26, GPMA_SALHS ;  B4SZH5, GPMA_SALNS ;  Q5PG75, GPMA_SALPA ;
DR   A9MTL3, GPMA_SALPB ;  C0PWW0, GPMA_SALPC ;  B5BC52, GPMA_SALPK ;
DR   B4TQR7, GPMA_SALSV ;  Q8Z8B2, GPMA_SALTI ;  Q8ZQS2, GPMA_SALTY ;
DR   A8GBA2, GPMA_SERP5 ;  B2TUY6, GPMA_SHIB3 ;  Q324G4, GPMA_SHIBS ;
DR   Q32IH0, GPMA_SHIDS ;  Q0T6Y5, GPMA_SHIF8 ;  P62710, GPMA_SHIFL ;
DR   Q3Z455, GPMA_SHISS ;  A6UEW3, GPMA_SINMW ;  Q2NUK6, GPMA_SODGM ;
DR   Q01YD0, GPMA_SOLUE ;  Q1GP88, GPMA_SPHAL ;  A5VB15, GPMA_SPHWW ;
DR   A7X656, GPMA_STAA1 ;  A6U4E6, GPMA_STAA2 ;  Q2FE81, GPMA_STAA3 ;
DR   Q2FVK8, GPMA_STAA8 ;  A5IVJ6, GPMA_STAA9 ;  Q2YVZ6, GPMA_STAAB ;
DR   Q5HDD9, GPMA_STAAC ;  A6QJQ5, GPMA_STAAE ;  P65708, GPMA_STAAM ;
DR   P99153, GPMA_STAAN ;  Q6GE17, GPMA_STAAR ;  Q6G6Q5, GPMA_STAAS ;
DR   A8YYG4, GPMA_STAAT ;  P65709, GPMA_STAAW ;  B9DL85, GPMA_STACT ;
DR   Q5HLI0, GPMA_STAEQ ;  Q8CN61, GPMA_STAES ;  Q4L8T0, GPMA_STAHJ ;
DR   Q49ZZ2, GPMA_STAS1 ;  Q3K1U2, GPMA_STRA1 ;  Q8E643, GPMA_STRA3 ;
DR   Q8E0G9, GPMA_STRA5 ;  Q82GB8, GPMA_STRAW ;  P33158, GPMA_STRCO ;
DR   C0M8R8, GPMA_STRE4 ;  B4U1Y5, GPMA_STREM ;  A8AW46, GPMA_STRGC ;
DR   B1VS80, GPMA_STRGG ;  B4SPL6, GPMA_STRM5 ;  B2FHH6, GPMA_STRMK ;
DR   P59161, GPMA_STRMU ;  Q99Z29, GPMA_STRP1 ;  Q04JB4, GPMA_STRP2 ;
DR   P0DD06, GPMA_STRP3 ;  B5E706, GPMA_STRP4 ;  Q5XB88, GPMA_STRP6 ;
DR   C1C8P5, GPMA_STRP7 ;  P65711, GPMA_STRP8 ;  Q1JAX0, GPMA_STRPB ;
DR   Q1JL20, GPMA_STRPC ;  Q1JG44, GPMA_STRPD ;  Q1J5W1, GPMA_STRPF ;
DR   A2RDV4, GPMA_STRPG ;  B1I720, GPMA_STRPI ;  B8ZM52, GPMA_STRPJ ;
DR   Q48SP2, GPMA_STRPM ;  P0A3Y3, GPMA_STRPN ;  P0DD07, GPMA_STRPQ ;
DR   B2IRR1, GPMA_STRPS ;  B5XM69, GPMA_STRPZ ;  P0A3Y4, GPMA_STRR6 ;
DR   A4W369, GPMA_STRS2 ;  C0MCW5, GPMA_STRS7 ;  A3CLS0, GPMA_STRSV ;
DR   Q5LZF1, GPMA_STRT1 ;  Q8VVB5, GPMA_STRT2 ;  Q03KA9, GPMA_STRTD ;
DR   B9DUS6, GPMA_STRU0 ;  C1CFM7, GPMA_STRZJ ;  C1CLZ5, GPMA_STRZP ;
DR   C1CSS1, GPMA_STRZT ;  C5BJ25, GPMA_TERTT ;  Q47KS8, GPMA_THEFY ;
DR   B0KBW9, GPMA_THEP3 ;  B0K4E2, GPMA_THEPX ;  Q8R7C8, GPMA_THETN ;
DR   Q73M14, GPMA_TREDE ;  P96121, GPMA_TREPA ;  B2S2B5, GPMA_TREPS ;
DR   Q83HD5, GPMA_TROW8 ;  Q83FQ7, GPMA_TROWT ;  B1GZZ1, GPMA_UNCTG ;
DR   C5CWV9, GPMA_VARPS ;  A1WDX2, GPMA_VEREI ;  Q8D2Y4, GPMA_WIGBR ;
DR   Q8PIM1, GPMA_XANAC ;  Q3BR53, GPMA_XANC5 ;  Q4UWV1, GPMA_XANC8 ;
DR   B0RQR7, GPMA_XANCB ;  Q8P7A1, GPMA_XANCP ;  Q2P5R0, GPMA_XANOM ;
DR   B2SRM8, GPMA_XANOP ;  Q5H2V7, GPMA_XANOR ;  A7IC75, GPMA_XANP2 ;
DR   B2I4U0, GPMA_XYLF2 ;  Q9PC88, GPMA_XYLFA ;  B0U2F2, GPMA_XYLFM ;
DR   Q87CZ1, GPMA_XYLFT ;  A1JRT1, GPMA_YERE8 ;  A7FKP6, GPMA_YERP3 ;
DR   Q1C964, GPMA_YERPA ;  B2K8R3, GPMA_YERPB ;  Q8ZGY5, GPMA_YERPE ;
DR   A9R3B3, GPMA_YERPG ;  Q1CFN6, GPMA_YERPN ;  A4TNS2, GPMA_YERPP ;
DR   Q66D83, GPMA_YERPS ;  B1JSU1, GPMA_YERPY ;  P30798, GPMA_ZYMMO ;
DR   A8ALW1, GPMB_CITK8 ;  A7ZVT7, GPMB_ECO24 ;  B7MNK4, GPMB_ECO45 ;
DR   B7LEP1, GPMB_ECO55 ;  P0A7A3, GPMB_ECO57 ;  B5Z4S7, GPMB_ECO5E ;
DR   B7NW76, GPMB_ECO7I ;  B7MTE3, GPMB_ECO81 ;  B7LXV9, GPMB_ECO8A ;
DR   C4ZT77, GPMB_ECOBW ;  B1XFK5, GPMB_ECODH ;  A8A8C4, GPMB_ECOHS ;
DR   A1AJW4, GPMB_ECOK1 ;  Q0T8R6, GPMB_ECOL5 ;  Q8FA40, GPMB_ECOL6 ;
DR   B1IS24, GPMB_ECOLC ;  P0A7A2, GPMB_ECOLI ;  B7NH70, GPMB_ECOLU ;
DR   B6I6P3, GPMB_ECOSE ;  B1LEK2, GPMB_ECOSM ;  Q1R246, GPMB_ECOUT ;
DR   A4W6B3, GPMB_ENT38 ;  A7MIJ0, GPMB_ENTS8 ;  B2VH13, GPMB_ERWT9 ;
DR   B7LNT7, GPMB_ESCF3 ;  B5Y264, GPMB_KLEP3 ;  A6TI09, GPMB_KLEP7 ;
DR   Q7N900, GPMB_PHOLL ;  B4EY52, GPMB_PROMH ;  B5F543, GPMB_SALA4 ;
DR   A9MR94, GPMB_SALAR ;  Q57G26, GPMB_SALCH ;  B5FTD9, GPMB_SALDC ;
DR   B5R3B7, GPMB_SALEP ;  B5R9W3, GPMB_SALG2 ;  B4TH18, GPMB_SALHS ;
DR   B4T4I9, GPMB_SALNS ;  Q5PK44, GPMB_SALPA ;  A9N7F5, GPMB_SALPB ;
DR   C0Q8F5, GPMB_SALPC ;  B5BAL1, GPMB_SALPK ;  B4TU55, GPMB_SALSV ;
DR   Q8Z0T4, GPMB_SALTI ;  Q8ZJU8, GPMB_SALTY ;  A8G9J4, GPMB_SERP5 ;
DR   B2TZS8, GPMB_SHIB3 ;  Q31SU3, GPMB_SHIBS ;  Q327K0, GPMB_SHIDS ;
DR   Q0SX17, GPMB_SHIF8 ;  P0A7A4, GPMB_SHIFL ;  Q3YTZ9, GPMB_SHISS ;
DR   A1JJB8, GPMB_YERE8 ;  A7FMF8, GPMB_YERP3 ;  Q1C0L5, GPMB_YERPA ;
DR   B2K3K5, GPMB_YERPB ;  Q8ZIP0, GPMB_YERPE ;  A9R032, GPMB_YERPG ;
DR   Q1CMX2, GPMB_YERPN ;  A4TQH5, GPMB_YERPP ;  Q66EU3, GPMB_YERPS ;
DR   B1JL20, GPMB_YERPY ;  Q8TMI6, GPMI1_METAC;  Q46D52, GPMI1_METBF;
DR   Q8TIY2, GPMI2_METAC;  Q46AE4, GPMI2_METBF;  B0CA77, GPMI_ACAM1 ;
DR   A9NF91, GPMI_ACHLI ;  Q6FFD5, GPMI_ACIAD ;  Q1ISS4, GPMI_ACIBL ;
DR   A4ST23, GPMI_AERS4 ;  Q8UAA5, GPMI_AGRT5 ;  B2UMU5, GPMI_AKKM8 ;
DR   Q5PAE9, GPMI_ANAMM ;  Q2GKV7, GPMI_ANAPZ ;  Q3MF89, GPMI_ANAVT ;
DR   Q06464, GPMI_ANTSP ;  A8EW05, GPMI_ARCB4 ;  Q2NJ40, GPMI_AYWBP ;
DR   A7Z8Y2, GPMI_BACA2 ;  A0RKS4, GPMI_BACAH ;  Q81X77, GPMI_BACAN ;
DR   Q72XY4, GPMI_BACC1 ;  A7GUR8, GPMI_BACCN ;  Q815K7, GPMI_BACCR ;
DR   Q631M1, GPMI_BACCZ ;  Q5LIL0, GPMI_BACFN ;  Q64ZN5, GPMI_BACFR ;
DR   Q9K716, GPMI_BACHD ;  Q6HBF2, GPMI_BACHK ;  Q65EN1, GPMI_BACLD ;
DR   D5DNA8, GPMI_BACMD ;  D5DVF4, GPMI_BACMQ ;  A8FHJ1, GPMI_BACP2 ;
DR   Q5WDK8, GPMI_BACSK ;  P39773, GPMI_BACSU ;  Q8A287, GPMI_BACTN ;
DR   A6L050, GPMI_BACV8 ;  A8FKM1, GPMI_CAMJ8 ;  A7H4U3, GPMI_CAMJD ;
DR   Q9PI71, GPMI_CAMJE ;  A1VYF1, GPMI_CAMJJ ;  Q5HW32, GPMI_CAMJR ;
DR   B3PGV8, GPMI_CELJU ;  A9WJ95, GPMI_CHLAA ;  B8GBF7, GPMI_CHLAD ;
DR   B9LBA2, GPMI_CHLSY ;  Q1R1J7, GPMI_CHRSD ;  Q7NSR8, GPMI_CHRVO ;
DR   Q97L53, GPMI_CLOAB ;  A7FQN9, GPMI_CLOB1 ;  A6LR07, GPMI_CLOB8 ;
DR   A7G9Y2, GPMI_CLOBL ;  Q181T7, GPMI_CLOD6 ;  A5N2N6, GPMI_CLOK5 ;
DR   A0PYP3, GPMI_CLONN ;  Q0TQY9, GPMI_CLOP1 ;  Q8XKU2, GPMI_CLOPE ;
DR   A9KPF4, GPMI_CLOPH ;  Q0STD7, GPMI_CLOPS ;  Q898R1, GPMI_CLOTE ;
DR   A3DBQ2, GPMI_CLOTH ;  Q47VY2, GPMI_COLP3 ;  A9KF70, GPMI_COXBN ;
DR   A9N970, GPMI_COXBR ;  Q83BH2, GPMI_COXBU ;  B8HVP2, GPMI_CYAP4 ;
DR   B7KGG1, GPMI_CYAP7 ;  B7K189, GPMI_CYAP8 ;  B1I0X9, GPMI_DESAP ;
DR   Q72BL6, GPMI_DESVH ;  A8LKJ5, GPMI_DINSH ;  A7ZTG6, GPMI_ECO24 ;
DR   Q8XDE9, GPMI_ECO57 ;  A8A677, GPMI_ECOHS ;  A1AHE9, GPMI_ECOK1 ;
DR   Q0TBJ4, GPMI_ECOL5 ;  Q8FCA6, GPMI_ECOL6 ;  B1IZH8, GPMI_ECOLC ;
DR   P37689, GPMI_ECOLI ;  Q3YRU6, GPMI_EHRCJ ;  Q2GGW3, GPMI_EHRCR ;
DR   Q5FFL8, GPMI_EHRRG ;  Q5HB16, GPMI_EHRRW ;  A4W533, GPMI_ENT38 ;
DR   A7MID1, GPMI_ENTS8 ;  A5FJ26, GPMI_FLAJ1 ;  A6H1H2, GPMI_FLAPJ ;
DR   B0TYM8, GPMI_FRAP2 ;  Q14GR4, GPMI_FRAT1 ;  A7NDJ7, GPMI_FRATF ;
DR   Q2A2B1, GPMI_FRATH ;  A0Q5M6, GPMI_FRATN ;  Q0BKX8, GPMI_FRATO ;
DR   Q5NFB1, GPMI_FRATT ;  A4IZ68, GPMI_FRATW ;  Q5KVE6, GPMI_GEOKA ;
DR   Q9X519, GPMI_GEOSE ;  Q747Q8, GPMI_GEOSL ;  A4ISP5, GPMI_GEOTN ;
DR   Q7NMK9, GPMI_GLOVI ;  Q5FU33, GPMI_GLUOX ;  Q6B8L5, GPMI_GRATL ;
DR   Q2SMA7, GPMI_HAHCH ;  Q5UXB9, GPMI_HALMA ;  B8CYG0, GPMI_HALOH ;
DR   Q9HNY7, GPMI_HALSA ;  Q18GK9, GPMI_HALWD ;  Q17X03, GPMI_HELAH ;
DR   Q7VGZ8, GPMI_HELHP ;  Q1CSQ0, GPMI_HELPH ;  Q9ZKM7, GPMI_HELPJ ;
DR   P56196, GPMI_HELPY ;  A9AYE8, GPMI_HERA2 ;  Q5QZA9, GPMI_IDILO ;
DR   C1DDB1, GPMI_LARHH ;  Q1MPK8, GPMI_LAWIP ;  Q5X7P2, GPMI_LEGPA ;
DR   A5IH96, GPMI_LEGPC ;  Q5ZY71, GPMI_LEGPH ;  Q5WZ43, GPMI_LEGPL ;
DR   Q72VB8, GPMI_LEPIC ;  P59173, GPMI_LEPIN ;  Q928I2, GPMI_LISIN ;
DR   Q71WX0, GPMI_LISMF ;  Q8Y4I4, GPMI_LISMO ;  A0ALE0, GPMI_LISW6 ;
DR   A0LDF3, GPMI_MAGSM ;  Q6F0W3, GPMI_MESFL ;  Q12UT0, GPMI_METBU ;
DR   Q1GZ82, GPMI_METFK ;  Q8PYF8, GPMI_METMA ;  B0JLN5, GPMI_MICAN ;
DR   Q2RLT9, GPMI_MOOTA ;  Q49006, GPMI_MYCCT ;  Q7NAQ5, GPMI_MYCGA ;
DR   P47669, GPMI_MYCGE ;  Q5ZZU2, GPMI_MYCH2 ;  Q4A7D1, GPMI_MYCH7 ;
DR   Q4A992, GPMI_MYCHJ ;  Q6Y8Q8, GPMI_MYCHP ;  Q6KHV9, GPMI_MYCMO ;
DR   Q6MSF0, GPMI_MYCMS ;  Q8EW33, GPMI_MYCPE ;  P75167, GPMI_MYCPN ;
DR   Q98QA7, GPMI_MYCPU ;  Q4A5A8, GPMI_MYCS5 ;  Q1DCX8, GPMI_MYXXD ;
DR   Q3IS17, GPMI_NATPD ;  Q3JF23, GPMI_NITOC ;  B2ITL6, GPMI_NOSP7 ;
DR   Q8YPL2, GPMI_NOSS1 ;  P59174, GPMI_OCEIH ;  Q6YQT8, GPMI_ONYPE ;
DR   A6LFB1, GPMI_PARD8 ;  A1B4Z9, GPMI_PARDP ;  Q3A1E5, GPMI_PELCD ;
DR   Q6LVL2, GPMI_PHOPR ;  P51379, GPMI_PORPU ;  Q1XDA8, GPMI_PORYE ;
DR   A2C4I0, GPMI_PROM1 ;  A2C700, GPMI_PROM3 ;  Q7VA78, GPMI_PROMA ;
DR   Q7V5U5, GPMI_PROMM ;  Q7V051, GPMI_PROMP ;  Q46J72, GPMI_PROMT ;
DR   Q48C87, GPMI_PSE14 ;  Q15PS5, GPMI_PSEA6 ;  A6VDP9, GPMI_PSEA7 ;
DR   Q02EN5, GPMI_PSEAB ;  Q9HU53, GPMI_PSEAE ;  Q1IG62, GPMI_PSEE4 ;
DR   Q4KJR8, GPMI_PSEF5 ;  Q3IIE4, GPMI_PSEHT ;  A4Y077, GPMI_PSEMY ;
DR   A5WA89, GPMI_PSEP1 ;  Q3KJH9, GPMI_PSEPF ;  B0KN11, GPMI_PSEPG ;
DR   Q88CX4, GPMI_PSEPK ;  P52832, GPMI_PSESM ;  Q4ZLR0, GPMI_PSEU2 ;
DR   Q4FTU8, GPMI_PSYA2 ;  A1SZI3, GPMI_PSYIN ;  Q7UFG7, GPMI_RHOBA ;
DR   Q6NCX7, GPMI_RHOPA ;  A3PMX9, GPMI_RHOS1 ;  Q3IZB8, GPMI_RHOS4 ;
DR   A4WWV3, GPMI_RHOS5 ;  B9KN62, GPMI_RHOSK ;  Q16D84, GPMI_ROSDO ;
DR   A1AXW7, GPMI_RUTMC ;  Q21NH1, GPMI_SACD2 ;  Q57IC9, GPMI_SALCH ;
DR   Q5PBZ2, GPMI_SALPA ;  A9MVK6, GPMI_SALPB ;  Q2S026, GPMI_SALRD ;
DR   Q8Z2F0, GPMI_SALTI ;  Q8ZL56, GPMI_SALTY ;  A8GLC2, GPMI_SERP5 ;
DR   A1S1L6, GPMI_SHEAM ;  A3DAN0, GPMI_SHEB5 ;  A6WHC7, GPMI_SHEB8 ;
DR   A9KUB8, GPMI_SHEB9 ;  Q12HV5, GPMI_SHEDO ;  Q07VW8, GPMI_SHEFN ;
DR   B0TLE6, GPMI_SHEHH ;  A3QJM4, GPMI_SHELP ;  P59175, GPMI_SHEON ;
DR   A8HAE0, GPMI_SHEPA ;  A4Y1E3, GPMI_SHEPC ;  A0KR77, GPMI_SHESA ;
DR   A8G1U9, GPMI_SHESH ;  Q0HP91, GPMI_SHESM ;  Q0I0Q6, GPMI_SHESR ;
DR   A1RQ95, GPMI_SHESW ;  Q31V09, GPMI_SHIBS ;  Q329P2, GPMI_SHIDS ;
DR   P59176, GPMI_SHIFL ;  Q3YVX7, GPMI_SHISS ;  Q5LLW1, GPMI_SILPO ;
DR   Q1GCX7, GPMI_SILST ;  Q5HHP2, GPMI_STAAC ;  P64269, GPMI_STAAM ;
DR   P64270, GPMI_STAAN ;  Q6GIL5, GPMI_STAAR ;  Q6GB55, GPMI_STAAS ;
DR   Q8NXL5, GPMI_STAAW ;  Q5HQV1, GPMI_STAEQ ;  Q8CPY4, GPMI_STAES ;
DR   Q4L4K6, GPMI_STAHJ ;  Q49W02, GPMI_STAS1 ;  Q9L214, GPMI_STRCO ;
DR   Q30Q40, GPMI_SULDN ;  Q67SW0, GPMI_SYMTH ;  Q31R18, GPMI_SYNE7 ;
DR   Q2JSV1, GPMI_SYNJA ;  Q2JIE9, GPMI_SYNJB ;  B1XJ47, GPMI_SYNP2 ;
DR   Q5N381, GPMI_SYNP6 ;  Q7U8U2, GPMI_SYNPX ;  P74507, GPMI_SYNY3 ;
DR   P59177, GPMI_THEEB ;  B9KYT9, GPMI_THERP ;  Q31E77, GPMI_THICR ;
DR   Q3SGA3, GPMI_THIDA ;  Q8L2S1, GPMI_TOBBP ;  Q117D6, GPMI_TRIEI ;
DR   B1AIH0, GPMI_UREP2 ;  Q9PQW1, GPMI_UREPA ;  B5ZAY8, GPMI_UREU1 ;
DR   A5CVF0, GPMI_VESOH ;  A5F3N4, GPMI_VIBC3 ;  Q9KV22, GPMI_VIBCH ;
DR   C3LR68, GPMI_VIBCM ;  Q5E8E9, GPMI_VIBF1 ;  B5FFX7, GPMI_VIBFM ;
DR   A7MX70, GPMI_VIBHB ;  Q87KZ5, GPMI_VIBPA ;  B7VHQ4, GPMI_VIBSL ;
DR   Q8DCW1, GPMI_VIBVU ;  Q7MGZ2, GPMI_VIBVY ;  Q73GR4, GPMI_WOLPM ;
DR   Q7M7W9, GPMI_WOLSU ;  Q5GSN3, GPMI_WOLTR ;  A1JHY1, GPMI_YERE8 ;
DR   A7FCU8, GPMI_YERP3 ;  Q1C282, GPMI_YERPA ;  Q8ZJN0, GPMI_YERPE ;
DR   Q1CD17, GPMI_YERPN ;  A4TSC2, GPMI_YERPP ;  Q66GC2, GPMI_YERPS ;
DR   Q9HIJ2, GPM_THEAC  ;  Q3SZ62, PGAM1_BOVIN;  Q5ZLN1, PGAM1_CHICK;
DR   P18669, PGAM1_HUMAN;  Q9DBJ1, PGAM1_MOUSE;  Q5RFB8, PGAM1_PONAB;
DR   P25113, PGAM1_RAT  ;  Q32KV0, PGAM2_BOVIN;  P15259, PGAM2_HUMAN;
DR   O70250, PGAM2_MOUSE;  P16290, PGAM2_RAT  ;  Q8N0Y7, PGAM4_HUMAN;
DR   Q8MKE8, PGAM4_PANTR;  Q54NE6, PGAM_DICDI ;  O04499, PMG1_ARATH ;
DR   P00950, PMG1_YEAST ;  Q9M9K1, PMG2_ARATH ;  Q12008, PMG2_YEAST ;
DR   Q12326, PMG3_YEAST ;  Q3T014, PMGE_BOVIN ;  P07738, PMGE_HUMAN ;
DR   Q4R6L7, PMGE_MACFA ;  P15327, PMGE_MOUSE ;  P07952, PMGE_RABIT ;
DR   P30792, PMGI_MAIZE ;  Q42908, PMGI_MESCR ;  O24246, PMGI_PRUDU ;
DR   P35493, PMGI_RICCO ;  P35494, PMGI_TOBAC ;  P82612, PMGY_CANAL ;
DR   P36623, PMGY_SCHPO ;  O94461, YFFL_SCHPO ;  Q9UT63, YKJ2_SCHPO ;
DR   Q12040, YO283_YEAST;  O94420, YQGD_SCHPO ;
//
ID   5.4.2.2
DE   Phosphoglucomutase.
AN   Glucose phosphomutase.
AN   Phosphoglucose mutase.
CA   Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.
CC   -!- Maximum activity is only obtained in the presence of alpha-D-glucose
CC       1,6-bisphosphate.
CC   -!- This bisphosphate is an intermediate in the reaction, being formed by
CC       transfer of a phosphate residue from the enzyme to the substrate,
CC       but the dissociation of bisphosphate from the enzyme complex is much
CC       slower than the overall isomerization.
CC   -!- Also, more slowly, catalyzes the interconversion of 1-phosphate and
CC       6-phosphate isomers of many other alpha-D-hexoses, and the
CC       interconversion of alpha-D-ribose 1-phosphate and 5-phosphate.
CC   -!- Formerly EC 2.7.5.1.
PR   PROSITE; PDOC00589;
DR   P26276, ALGC_PSEAE ;  Q88C93, ALGC_PSEPK ;  Q88BD4, ALGC_PSESM ;
DR   P18159, PGCA_BACSU ;  Q2FE11, PGCA_STAA3 ;  Q2FVC1, PGCA_STAA8 ;
DR   Q2YW66, PGCA_STAAB ;  Q5HD61, PGCA_STAAC ;  Q99RE2, PGCA_STAAM ;
DR   Q7A3K7, PGCA_STAAN ;  Q6GDU9, PGCA_STAAR ;  Q6G6I3, PGCA_STAAS ;
DR   Q8NUV4, PGCA_STAAW ;  Q5HLD2, PGCA_STAEQ ;  Q8CN38, PGCA_STAES ;
DR   Q4L9R5, PGCA_STAHJ ;  Q49WH7, PGCA_STAS1 ;  Q08DP0, PGM1_BOVIN ;
DR   Q23919, PGM1_DICDI ;  P36871, PGM1_HUMAN ;  Q4R5E4, PGM1_MACFA ;
DR   Q9D0F9, PGM1_MOUSE ;  P47244, PGM1_PARTE ;  P00949, PGM1_RABIT ;
DR   P38652, PGM1_RAT   ;  P33401, PGM1_YEAST ;  Q54UQ2, PGM2_DICDI ;
DR   Q96G03, PGM2_HUMAN ;  Q7TSV4, PGM2_MOUSE ;  O02606, PGM2_PARTE ;
DR   Q5RFI8, PGM2_PONAB ;  O74478, PGM2_SCHPO ;  P37012, PGM2_YEAST ;
DR   Q03262, PGM3_YEAST ;  O49299, PGMC1_ARATH;  P93804, PGMC1_MAIZE;
DR   Q9SGC1, PGMC2_ARATH;  P93805, PGMC2_MAIZE;  Q9SNX2, PGMC_BROIN ;
DR   P93262, PGMC_MESCR ;  Q9SM60, PGMC_PEA   ;  Q9ZSQ4, PGMC_POPTN ;
DR   Q9M4G4, PGMC_SOLTU ;  Q9SCY0, PGMP_ARATH ;  Q9SMM0, PGMP_BRANA ;
DR   Q9SM59, PGMP_PEA   ;  Q9M4G5, PGMP_SOLTU ;  Q4WY53, PGM_ASPFU  ;
DR   P57749, PGM_ASPOR  ;  Q9VUY9, PGM_DROME  ;  Q7KHA1, PGM_DROSI  ;
DR   P36938, PGM_ECOLI  ;  Q9P931, PGM_EMENI  ;  O18719, PGM_ENTDI  ;
DR   O15820, PGM_ENTHI  ;  P38569, PGM_GLUXY  ;  P40390, PGM_NEIGO  ;
DR   P57002, PGM_NEIMA  ;  P40391, PGM_NEIMB  ;  P39671, PGM_RHIRD  ;
DR   O74374, PGM_SCHPO  ;  B0RVK5, XANA_XANCB ;  P0C7J2, XANA_XANCP ;
//
ID   5.4.2.3
DE   Phosphoacetylglucosamine mutase.
AN   Acetylglucosamine phosphomutase.
AN   N-acetylglucosamine-phosphate mutase.
CA   N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine
CA   6-phosphate.
CC   -!- Activated by N-acetyl-alpha-D-glucosamine 1,6-bisphosphate.
CC   -!- Formerly EC 2.7.5.2.
PR   PROSITE; PDOC00589;
DR   P57750, AGM1_ARATH ;  Q9P4V2, AGM1_CANAL ;  Q8SSL7, AGM1_ENCCU ;
DR   O95394, AGM1_HUMAN ;  Q9CYR6, AGM1_MOUSE ;  Q6ZDQ1, AGM1_ORYSJ ;
DR   Q09687, AGM1_SCHPO ;  P38628, AGM1_YEAST ;  Q09770, AGM2_SCHPO ;
//
ID   5.4.2.4
DE   Bisphosphoglycerate mutase.
AN   2,3-bisphosphoglycerate mutase.
AN   2,3-bisphosphoglycerate synthase.
AN   2,3-diphosphoglycerate mutase.
AN   Bisphosphoglycerate synthase.
AN   BPGM.
AN   Diphosphoglycerate mutase.
AN   Diphosphoglyceromutase.
AN   Glycerate phosphomutase.
CA   3-phospho-D-glyceroyl phosphate = 2,3-bisphospho-D-glycerate.
CC   -!- In the direction shown, the enzyme is phosphorylated by
CC       3-phosphoglyceroyl phosphate to give phosphoenzyme and
CC       3-phosphoglycerate.
CC   -!- The latter is rephosphorylated by the enzyme to yield 2,3-
CC       diphosphoglycerate, but this reaction is slowed down by dissociation
CC       of 3-phosphoglycerate from the enzyme, which is therefore more active
CC       in the presence of added 3-phosphoglycerate.
CC   -!- Also catalyzes, slowly, the reactions of EC 3.1.3.13 and EC 5.4.2.1.
CC   -!- Formerly EC 2.7.5.4.
PR   PROSITE; PDOC00158;
DR   Q3SZ62, PGAM1_BOVIN;  Q5ZLN1, PGAM1_CHICK;  P18669, PGAM1_HUMAN;
DR   Q9DBJ1, PGAM1_MOUSE;  Q5RFB8, PGAM1_PONAB;  P25113, PGAM1_RAT  ;
DR   Q32KV0, PGAM2_BOVIN;  P15259, PGAM2_HUMAN;  O70250, PGAM2_MOUSE;
DR   P16290, PGAM2_RAT  ;  Q8N0Y7, PGAM4_HUMAN;  Q8MKE8, PGAM4_PANTR;
DR   Q54NE6, PGAM_DICDI ;  Q3T014, PMGE_BOVIN ;  P07738, PMGE_HUMAN ;
DR   Q4R6L7, PMGE_MACFA ;  P15327, PMGE_MOUSE ;  P07952, PMGE_RABIT ;
//
ID   5.4.2.5
DE   Phosphoglucomutase (glucose-cofactor).
AN   Glucose phosphomutase.
AN   Glucose-1-phosphate phosphotransferase.
CA   Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.
CC   -!- Activated by D-glucose, which probably acts as an acceptor for a
CC       phosphate residue from the substrate, thus being itself converted
CC       into the product.
CC   -!- Formerly EC 2.7.5.5.
//
ID   5.4.2.6
DE   Beta-phosphoglucomutase.
CA   Beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate.
DR   O06995, PGMB_BACSU ;  P77366, PGMB_ECOLI ;  P71447, PGMB_LACLA ;
//
ID   5.4.2.7
DE   Phosphopentomutase.
AN   Deoxyribomutase.
AN   Deoxyribose phosphomutase.
AN   Phosphodeoxyribomutase.
CA   Alpha-D-ribose 1-phosphate = D-ribose 5-phosphate.
CC   -!- Also converts 2-deoxy-alpha-D-ribose 1-phosphate into 2-deoxy-alpha-
CC       D-ribose 5-phosphate.
CC   -!- Alpha-D-ribose 1,5-bisphosphate, 2-deoxy-alpha-D-ribose 1,5-
CC       bisphosphate, or alpha-D-glucose 1,6-bisphosphate can act as
CC       cofactor.
CC   -!- Formerly EC 2.7.5.6.
DR   Q3K0S1, DEOB1_STRA1;  Q3JYQ5, DEOB2_STRA1;  A9NG16, DEOB_ACHLI ;
DR   A6VM02, DEOB_ACTSZ ;  A0KPE2, DEOB_AERHH ;  A4SRU2, DEOB_AERS4 ;
DR   B9J6V9, DEOB_AGRRK ;  Q8UJ04, DEOB_AGRT5 ;  B9JYP7, DEOB_AGRVS ;
DR   B6ENG5, DEOB_ALISL ;  A6TR59, DEOB_ALKMQ ;  A8MFH2, DEOB_ALKOO ;
DR   B8JEI1, DEOB_ANAD2 ;  Q2IPF0, DEOB_ANADE ;  A7H8W4, DEOB_ANADF ;
DR   B4UF79, DEOB_ANASK ;  C3P7M3, DEOB_BACAA ;  C3LIV3, DEOB_BACAC ;
DR   A0RI91, DEOB_BACAH ;  Q81ME0, DEOB_BACAN ;  B7JLU2, DEOB_BACC0 ;
DR   Q731L0, DEOB_BACC1 ;  B7IWK1, DEOB_BACC2 ;  C1EQW1, DEOB_BACC3 ;
DR   B7H979, DEOB_BACC4 ;  B7HN67, DEOB_BACC7 ;  B9IWV1, DEOB_BACCQ ;
DR   Q818Z9, DEOB_BACCR ;  Q635J3, DEOB_BACCZ ;  Q9KCN9, DEOB_BACHD ;
DR   Q6HE79, DEOB_BACHK ;  Q65HT9, DEOB_BACLD ;  A8FET4, DEOB_BACP2 ;
DR   Q5WH37, DEOB_BACSK ;  P46353, DEOB_BACSU ;  A9VFJ2, DEOB_BACWK ;
DR   A4YPV1, DEOB_BRASO ;  C0ZC50, DEOB_BREBN ;  B8D9W4, DEOB_BUCA5 ;
DR   P57607, DEOB_BUCAI ;  Q8K936, DEOB_BUCAP ;  B8D866, DEOB_BUCAT ;
DR   Q89A57, DEOB_BUCBP ;  Q3AAQ2, DEOB_CARHZ ;  Q1QZC2, DEOB_CHRSD ;
DR   Q7NRT1, DEOB_CHRVO ;  Q97HE6, DEOB_CLOAB ;  A6LY33, DEOB_CLOB8 ;
DR   B2V0J5, DEOB_CLOBA ;  B2TKE1, DEOB_CLOBB ;  Q18B86, DEOB_CLOD6 ;
DR   B9E115, DEOB_CLOK1 ;  A5N7K3, DEOB_CLOK5 ;  A0PYX6, DEOB_CLONN ;
DR   Q0TU57, DEOB_CLOP1 ;  Q8XNE7, DEOB_CLOPE ;  A9KK75, DEOB_CLOPH ;
DR   Q0SW00, DEOB_CLOPS ;  Q894Z2, DEOB_CLOTE ;  A3DD83, DEOB_CLOTH ;
DR   Q483R0, DEOB_COLP3 ;  Q9RSI9, DEOB_DEIRA ;  B8FPN5, DEOB_DESHD ;
DR   Q24V41, DEOB_DESHY ;  B5YF73, DEOB_DICT6 ;  B8E109, DEOB_DICTD ;
DR   A7ZVS6, DEOB_ECO24 ;  B7UR11, DEOB_ECO27 ;  B7MNJ0, DEOB_ECO45 ;
DR   B7LEM9, DEOB_ECO55 ;  P0A6K8, DEOB_ECO57 ;  B5Z4R5, DEOB_ECO5E ;
DR   B7NW63, DEOB_ECO7I ;  B7MTC9, DEOB_ECO81 ;  B7LXU5, DEOB_ECO8A ;
DR   C4ZT65, DEOB_ECOBW ;  B1XFJ3, DEOB_ECODH ;  A8A8B2, DEOB_ECOHS ;
DR   A1AJV0, DEOB_ECOK1 ;  Q0T8T0, DEOB_ECOL5 ;  P0A6K7, DEOB_ECOL6 ;
DR   B1IS36, DEOB_ECOLC ;  P0A6K6, DEOB_ECOLI ;  B7NH51, DEOB_ECOLU ;
DR   B6I6N0, DEOB_ECOSE ;  B1LEI8, DEOB_ECOSM ;  Q1R260, DEOB_ECOUT ;
DR   C5BHJ4, DEOB_EDWI9 ;  B2KBT7, DEOB_ELUMP ;  A4W6A0, DEOB_ENT38 ;
DR   Q839I2, DEOB_ENTFA ;  A7MGA8, DEOB_ENTS8 ;  Q6D990, DEOB_ERWCT ;
DR   B2VH52, DEOB_ERWT9 ;  B7LNS3, DEOB_ESCF3 ;  C4ZB25, DEOB_EUBR3 ;
DR   B1YM95, DEOB_EXIS2 ;  Q5KXI7, DEOB_GEOKA ;  O24821, DEOB_GEOSE ;
DR   Q2SHN3, DEOB_HAHCH ;  Q17YP1, DEOB_HELAH ;  B6JN18, DEOB_HELP2 ;
DR   B5Z8H3, DEOB_HELPG ;  Q1CS87, DEOB_HELPH ;  Q9ZK37, DEOB_HELPJ ;
DR   B2UUU2, DEOB_HELPS ;  P56195, DEOB_HELPY ;  A9B2N4, DEOB_HERA2 ;
DR   Q5QXT9, DEOB_IDILO ;  B5Y275, DEOB_KLEP3 ;  C5CHD5, DEOB_KOSOT ;
DR   Q03Q51, DEOB_LACBA ;  Q9CH12, DEOB_LACLA ;  O32808, DEOB_LACLM ;
DR   Q02ZT2, DEOB_LACLS ;  A5VHR0, DEOB_LACRD ;  B2G590, DEOB_LACRJ ;
DR   Q38XI1, DEOB_LACSS ;  Q5X7B2, DEOB_LEGPA ;  A5IGR8, DEOB_LEGPC ;
DR   Q5ZXU2, DEOB_LEGPH ;  Q5WYR0, DEOB_LEGPL ;  Q92A54, DEOB_LISIN ;
DR   C1KWQ5, DEOB_LISMC ;  Q71Y60, DEOB_LISMF ;  B8DBX2, DEOB_LISMH ;
DR   Q8Y5V1, DEOB_LISMO ;  A0AK66, DEOB_LISW6 ;  B9E8I3, DEOB_MACCJ ;
DR   Q11AV9, DEOB_MESSB ;  B7KXI3, DEOB_METC4 ;  A9W427, DEOB_METEP ;
DR   B8IJW7, DEOB_METNO ;  B1ZIG8, DEOB_METPB ;  B1LYJ9, DEOB_METRJ ;
DR   B0UPC1, DEOB_METS4 ;  Q2RID0, DEOB_MOOTA ;  Q98QT4, DEOB_MYCPU ;
DR   Q8EQ67, DEOB_OCEIH ;  C6DKL9, DEOB_PECCP ;  Q3A248, DEOB_PELCD ;
DR   Q7N931, DEOB_PHOLL ;  Q6LUH2, DEOB_PHOPR ;  B4EWA2, DEOB_PROMH ;
DR   Q3ICU9, DEOB_PSEHT ;  A1SYK3, DEOB_PSYIN ;  Q2KDR4, DEOB_RHIEC ;
DR   Q1MMV6, DEOB_RHIL3 ;  Q98BG5, DEOB_RHILO ;  B5ZXI4, DEOB_RHILW ;
DR   Q92T47, DEOB_RHIME ;  C3MBH5, DEOB_RHISN ;  B5F526, DEOB_SALA4 ;
DR   A9MRA5, DEOB_SALAR ;  Q57G39, DEOB_SALCH ;  B5FTC7, DEOB_SALDC ;
DR   B5R2J8, DEOB_SALEP ;  B5R9V1, DEOB_SALG2 ;  B4TH01, DEOB_SALHS ;
DR   B4T4H2, DEOB_SALNS ;  Q5PK21, DEOB_SALPA ;  A9N7E1, DEOB_SALPB ;
DR   C0Q7M5, DEOB_SALPC ;  B5BAJ9, DEOB_SALPK ;  B4TU43, DEOB_SALSV ;
DR   P63924, DEOB_SALTI ;  P63923, DEOB_SALTY ;  A8G9H8, DEOB_SERP5 ;
DR   A1S476, DEOB_SHEAM ;  B8E6P6, DEOB_SHEB2 ;  A3D7J2, DEOB_SHEB5 ;
DR   A6WRB6, DEOB_SHEB8 ;  A9KZ78, DEOB_SHEB9 ;  Q12QG1, DEOB_SHEDO ;
DR   Q086F8, DEOB_SHEFN ;  B0TQ89, DEOB_SHEHH ;  A3QGT1, DEOB_SHELP ;
DR   Q8EHK2, DEOB_SHEON ;  A8H726, DEOB_SHEPA ;  A4Y9A6, DEOB_SHEPC ;
DR   A0KU09, DEOB_SHESA ;  A8FYQ7, DEOB_SHESH ;  Q0HLE8, DEOB_SHESM ;
DR   Q0HXQ2, DEOB_SHESR ;  A1RH89, DEOB_SHESW ;  B1KRP6, DEOB_SHEWM ;
DR   B2TZR6, DEOB_SHIB3 ;  Q31SV6, DEOB_SHIBS ;  Q327L3, DEOB_SHIDS ;
DR   Q0SX28, DEOB_SHIF8 ;  P0A6K9, DEOB_SHIFL ;  Q3YU10, DEOB_SHISS ;
DR   A6UET6, DEOB_SINMW ;  Q2NW04, DEOB_SODGM ;  A7WXA5, DEOB_STAA1 ;
DR   A6TXS4, DEOB_STAA2 ;  Q2FKC0, DEOB_STAA3 ;  Q2G227, DEOB_STAA8 ;
DR   A5IP09, DEOB_STAA9 ;  Q2YUU3, DEOB_STAAB ;  Q5HJM9, DEOB_STAAC ;
DR   A6QDC3, DEOB_STAAE ;  P63925, DEOB_STAAM ;  P99100, DEOB_STAAN ;
DR   Q6GKG6, DEOB_STAAR ;  Q6GCY5, DEOB_STAAS ;  A8YZ65, DEOB_STAAT ;
DR   P63926, DEOB_STAAW ;  B9DKM0, DEOB_STACT ;  Q5HM86, DEOB_STAEQ ;
DR   Q8CNH9, DEOB_STAES ;  Q4L817, DEOB_STAHJ ;  Q49Z82, DEOB_STAS1 ;
DR   Q8CMH7, DEOB_STRA3 ;  Q8CMH6, DEOB_STRA5 ;  C0M7X5, DEOB_STRE4 ;
DR   B4U3E6, DEOB_STREM ;  A8AXN8, DEOB_STRGC ;  Q8DTU0, DEOB_STRMU ;
DR   P63927, DEOB_STRP1 ;  Q04L81, DEOB_STRP2 ;  P0DA60, DEOB_STRP3 ;
DR   B5E3K2, DEOB_STRP4 ;  Q5XCL5, DEOB_STRP6 ;  C1C6G4, DEOB_STRP7 ;
DR   Q8P1C4, DEOB_STRP8 ;  Q1JC88, DEOB_STRPB ;  Q1JM72, DEOB_STRPC ;
DR   Q1JHB7, DEOB_STRPD ;  Q1J736, DEOB_STRPF ;  A2RF12, DEOB_STRPG ;
DR   B1IAZ8, DEOB_STRPI ;  B8ZNH9, DEOB_STRPJ ;  Q48U17, DEOB_STRPM ;
DR   Q97RI6, DEOB_STRPN ;  P0DA61, DEOB_STRPQ ;  B5XL08, DEOB_STRPZ ;
DR   Q8DQD0, DEOB_STRR6 ;  C0ME45, DEOB_STRS7 ;  A3CNA8, DEOB_STRSV ;
DR   A4VWC5, DEOB_STRSY ;  Q5LZM6, DEOB_STRT1 ;  Q5M482, DEOB_STRT2 ;
DR   Q03KJ9, DEOB_STRTD ;  Q9EUQ2, DEOB_STRTR ;  B9DUK3, DEOB_STRU0 ;
DR   C1CDH7, DEOB_STRZJ ;  C1CJR8, DEOB_STRZP ;  C1CS61, DEOB_STRZT ;
DR   Q67ND8, DEOB_SYMTH ;  A8F670, DEOB_THELT ;  Q9WY14, DEOB_THEMA ;
DR   A5IKQ4, DEOB_THEP1 ;  B0KCA9, DEOB_THEP3 ;  B0K346, DEOB_THEPX ;
DR   Q8RCG6, DEOB_THETN ;  C4LAY9, DEOB_TOLAT ;  A5F5U0, DEOB_VIBC3 ;
DR   Q9KPL9, DEOB_VIBCH ;  C3LQC0, DEOB_VIBCM ;  Q5E7J5, DEOB_VIBF1 ;
DR   B5FAA0, DEOB_VIBFM ;  A7MUW4, DEOB_VIBHB ;  Q87M24, DEOB_VIBPA ;
DR   Q8DBT0, DEOB_VIBVU ;  Q7MI40, DEOB_VIBVY ;  A1JJ99, DEOB_YERE8 ;
DR   A7FMH3, DEOB_YERP3 ;  Q1C165, DEOB_YERPA ;  B2K3J0, DEOB_YERPB ;
DR   Q8ZIQ3, DEOB_YERPE ;  A9R047, DEOB_YERPG ;  Q1CMY8, DEOB_YERPN ;
DR   A4TQJ1, DEOB_YERPP ;  Q66EV8, DEOB_YERPS ;  B1JL35, DEOB_YERPY ;
DR   Q96G03, PGM2_HUMAN ;  Q7TSV4, PGM2_MOUSE ;  Q5RFI8, PGM2_PONAB ;
//
ID   5.4.2.8
DE   Phosphomannomutase.
AN   Phosphomannose mutase.
CA   Alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.
CC   -!- Alpha-D-mannose 1,6-bisphosphate or alpha-D-glucose 1,6-bisphosphate
CC       can act as cofactor.
CC   -!- Formerly EC 2.7.5.7.
PR   PROSITE; PDOC00589;
DR   P26276, ALGC_PSEAE ;  Q88C93, ALGC_PSEPK ;  Q88BD4, ALGC_PSESM ;
DR   P45632, EXOC_AZOBR ;  O85343, MANB_ECO57 ;  P24175, MANB_ECOLI ;
DR   Q48463, MANB_KLEPN ;  Q57842, MANB_METJA ;  P47299, MANB_MYCGE ;
DR   P47723, MANB_MYCPI ;  P75050, MANB_MYCPN ;  Q01411, MANB_SALMO ;
DR   P26341, MANB_SALTY ;  P55356, NOEK_RHISN ;  Q54X03, PMM1_DICDI ;
DR   Q92871, PMM1_HUMAN ;  O35621, PMM1_MOUSE ;  Q3SZJ9, PMM2_BOVIN ;
DR   Q86B09, PMM2_DICDI ;  O15305, PMM2_HUMAN ;  Q60HD6, PMM2_MACFA ;
DR   Q9Z2M7, PMM2_MOUSE ;  O80840, PMM_ARATH  ;  O43976, PMM_BABBO  ;
DR   Q9XUE6, PMM_CAEEL  ;  P31353, PMM_CANAL  ;  Q9VTZ6, PMM_DROME  ;
DR   Q8SVM5, PMM_ENCCU  ;  Q259G4, PMM_ORYSI  ;  Q7XPW5, PMM_ORYSJ  ;
DR   Q9UTJ2, PMM_SCHPO  ;  Q1W377, PMM_SOLLC  ;  Q1W376, PMM_SOYBN  ;
DR   Q1W375, PMM_TOBAC  ;  Q1W374, PMM_WHEAT  ;  P07283, PMM_YEAST  ;
DR   Q06951, RFBB_VIBCH ;  P37742, RFBK7_ECOLX;  P37755, RFBK9_ECOLX;
DR   Q00330, RFBK_SALMU ;  P26405, RFBK_SALTY ;  B0RVK5, XANA_XANCB ;
DR   P0C7J2, XANA_XANCP ;  Q57290, Y740_HAEIN ;
//
ID   5.4.2.9
DE   Phosphoenolpyruvate mutase.
AN   PEP mutase.
AN   PEP phosphomutase.
AN   Phosphoenolpyruvate phosphomutase.
CA   Phosphoenolpyruvate = 3-phosphonopyruvate.
CC   -!- Involved in the biosynthesis of the C-P bond, although the
CC       equilibrium greatly favors phosphoenolpyruvate.
DR   P56839, PEPM_MYTED ;  P29247, PEPM_STRHY ;  O86937, PEPM_STRVR ;
DR   P33182, PEPM_TETPY ;
//
ID   5.4.2.10
DE   Phosphoglucosamine mutase.
CA   Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate.
CC   -!- The enzyme is involved in the pathway for bacterial cell-wall
CC       peptidoglycan and lipopolysaccharide biosyntheses, being an essential
CC       step in the pathway for UDP-N-acetylglucosamine biosynthesis.
CC   -!- The enzyme from Escherichia coli is activated by phosphorylation and
CC       can be autophosphorylated in vitro by alpha-D-glucosamine 1,6-
CC       bisphosphate, which is an intermediate in the reaction, alpha-D-
CC       glucose 1,6-bisphosphate or ATP.
CC   -!- It can also catalyze the interconversion of alpha-D-glucose
CC       1-phosphate and alpha-D-glucose 6-phosphate, although at a much lower
CC       rate.
DR   A1S457, GLMM1_SHEAM;  A6WRH3, GLMM1_SHEB8;  A9KZX6, GLMM1_SHEB9;
DR   Q086H7, GLMM1_SHEFN;  Q0HLG6, GLMM1_SHESM;  Q0HXS0, GLMM1_SHESR;
DR   A1S7U2, GLMM2_SHEAM;  A6WQD3, GLMM2_SHEB8;  A9KVT4, GLMM2_SHEB9;
DR   Q07ZA3, GLMM2_SHEFN;  Q0HKK5, GLMM2_SHESM;  Q0HWV8, GLMM2_SHESR;
DR   B0C132, GLMM_ACAM1 ;  A1TQF3, GLMM_ACIAC ;  Q6F717, GLMM_ACIAD ;
DR   B7GV90, GLMM_ACIB3 ;  B7ICC7, GLMM_ACIB5 ;  B2I1H8, GLMM_ACIBC ;
DR   Q1IV19, GLMM_ACIBL ;  B0VNX9, GLMM_ACIBS ;  A3M9W5, GLMM_ACIBT ;
DR   B0V9C8, GLMM_ACIBY ;  A0LRQ7, GLMM_ACIC1 ;  A5FWQ4, GLMM_ACICJ ;
DR   B9MI07, GLMM_ACIET ;  A1W8G7, GLMM_ACISJ ;  A3N2A2, GLMM_ACTP2 ;
DR   B3H286, GLMM_ACTP7 ;  B0BR43, GLMM_ACTPJ ;  A6VP84, GLMM_ACTSZ ;
DR   A0KNE8, GLMM_AERHH ;  A4SJR0, GLMM_AERS4 ;  B9J9H0, GLMM_AGRRK ;
DR   Q8U9L9, GLMM_AGRT5 ;  B9JRY5, GLMM_AGRVS ;  Q0VSS6, GLMM_ALCBS ;
DR   Q0A772, GLMM_ALHEH ;  B6END8, GLMM_ALISL ;  A6TW06, GLMM_ALKMQ ;
DR   A8MJD2, GLMM_ALKOO ;  B4RXA8, GLMM_ALTMD ;  Q2IHZ5, GLMM_ANADE ;
DR   A7HCU0, GLMM_ANADF ;  B9KJ94, GLMM_ANAMF ;  Q5PA34, GLMM_ANAMM ;
DR   B9MMU5, GLMM_ANATD ;  Q3M6L2, GLMM_ANAVT ;  B7GIY9, GLMM_ANOFW ;
DR   A8EQZ2, GLMM_ARCB4 ;  Q5P1F7, GLMM_AROAE ;  A1R8Q0, GLMM_ARTAT ;
DR   B8HCH4, GLMM_ARTCA ;  A0JZ25, GLMM_ARTS2 ;  A8HUR7, GLMM_AZOC5 ;
DR   A1K5A1, GLMM_AZOSB ;  C1DFL3, GLMM_AZOVD ;  A7Z0V3, GLMM_BACA2 ;
DR   C3PAL5, GLMM_BACAA ;  C3LJZ1, GLMM_BACAC ;  A0R8M4, GLMM_BACAH ;
DR   Q81VN7, GLMM_BACAN ;  B7JL64, GLMM_BACC0 ;  Q73F50, GLMM_BACC1 ;
DR   B7ITV9, GLMM_BACC2 ;  C1EU11, GLMM_BACC3 ;  B7HJK3, GLMM_BACC4 ;
DR   B7HQZ0, GLMM_BACC7 ;  A7GK66, GLMM_BACCN ;  B9J0F1, GLMM_BACCQ ;
DR   Q81J03, GLMM_BACCR ;  Q63H45, GLMM_BACCZ ;  Q9KG46, GLMM_BACHD ;
DR   Q6HPL3, GLMM_BACHK ;  Q65P47, GLMM_BACLD ;  A8F9E6, GLMM_BACP2 ;
DR   Q5WLG9, GLMM_BACSK ;  O34824, GLMM_BACSU ;  A9VPC3, GLMM_BACWK ;
DR   A1URA6, GLMM_BARBK ;  Q6G5P7, GLMM_BARHE ;  Q6FYQ7, GLMM_BARQU ;
DR   A9IYI0, GLMM_BART1 ;  Q1LSK5, GLMM_BAUCH ;  Q6MLS4, GLMM_BDEBA ;
DR   B2IGB3, GLMM_BEII9 ;  B8DWH9, GLMM_BIFA0 ;  A1A2Z2, GLMM_BIFAA ;
DR   B3DTC2, GLMM_BIFLD ;  Q8G533, GLMM_BIFLO ;  B7GUF2, GLMM_BIFLS ;
DR   Q7VQM5, GLMM_BLOFL ;  Q493U0, GLMM_BLOPB ;  Q2KVQ6, GLMM_BORA1 ;
DR   Q7WMD0, GLMM_BORBR ;  Q7W8R3, GLMM_BORPA ;  A9HYU0, GLMM_BORPD ;
DR   Q7VZ59, GLMM_BORPE ;  Q89DN1, GLMM_BRAJA ;  A5ECX6, GLMM_BRASB ;
DR   A4Z0D8, GLMM_BRASO ;  C0ZIM8, GLMM_BREBN ;  Q2YQH8, GLMM_BRUA2 ;
DR   Q57BJ0, GLMM_BRUAB ;  A9M7I9, GLMM_BRUC2 ;  Q8YIU8, GLMM_BRUME ;
DR   A5VS47, GLMM_BRUO2 ;  A9WWG7, GLMM_BRUSI ;  Q8FZ13, GLMM_BRUSU ;
DR   B8D9G5, GLMM_BUCA5 ;  P57461, GLMM_BUCAI ;  B8D7R7, GLMM_BUCAT ;
DR   Q89AF3, GLMM_BUCBP ;  B1YMW5, GLMM_BURA4 ;  Q1BXC7, GLMM_BURCA ;
DR   B1JZF2, GLMM_BURCC ;  A0K6C4, GLMM_BURCH ;  B4E5F6, GLMM_BURCJ ;
DR   Q0BGI9, GLMM_BURCM ;  A9ACL5, GLMM_BURM1 ;  A3MIQ6, GLMM_BURM7 ;
DR   A2S3Q4, GLMM_BURM9 ;  Q62L77, GLMM_BURMA ;  A1V322, GLMM_BURMS ;
DR   A3NTW6, GLMM_BURP0 ;  Q3JTT2, GLMM_BURP1 ;  A3N856, GLMM_BURP6 ;
DR   B2JFP2, GLMM_BURP8 ;  B2SZR6, GLMM_BURPP ;  Q63V83, GLMM_BURPS ;
DR   Q39HM9, GLMM_BURS3 ;  Q2SUW3, GLMM_BURTA ;  A4JDA9, GLMM_BURVG ;
DR   Q13W50, GLMM_BURXL ;  A4XH45, GLMM_CALS8 ;  A7ZB08, GLMM_CAMC1 ;
DR   A7GW10, GLMM_CAMC5 ;  A0RRK2, GLMM_CAMFF ;  A7I458, GLMM_CAMHC ;
DR   A8FKE8, GLMM_CAMJ8 ;  A7H514, GLMM_CAMJD ;  Q9PIE2, GLMM_CAMJE ;
DR   A1VY80, GLMM_CAMJJ ;  Q5HWA7, GLMM_CAMJR ;  B9KE78, GLMM_CAMLR ;
DR   Q3AAK3, GLMM_CARHZ ;  B8GXK7, GLMM_CAUCN ;  Q9ABV3, GLMM_CAUCR ;
DR   B0T1V6, GLMM_CAUSK ;  B3PLQ1, GLMM_CELJU ;  Q5L588, GLMM_CHLAB ;
DR   Q821Z6, GLMM_CHLCV ;  Q255P2, GLMM_CHLFF ;  Q9PLA5, GLMM_CHLMU ;
DR   Q9Z6U1, GLMM_CHLPN ;  B0B944, GLMM_CHLT2 ;  Q3KKM5, GLMM_CHLTA ;
DR   B0BAS3, GLMM_CHLTB ;  O84822, GLMM_CHLTR ;  Q1QSY5, GLMM_CHRSD ;
DR   Q7NRI6, GLMM_CHRVO ;  A8AQ65, GLMM_CITK8 ;  A5CU74, GLMM_CLAM3 ;
DR   B0RB78, GLMM_CLAMS ;  Q97LS0, GLMM_CLOAB ;  A7FZ14, GLMM_CLOB1 ;
DR   C3KVJ0, GLMM_CLOB6 ;  A6LPX0, GLMM_CLOB8 ;  B2UYH3, GLMM_CLOBA ;
DR   B2TIN7, GLMM_CLOBB ;  A5I7E5, GLMM_CLOBH ;  C1FMP0, GLMM_CLOBJ ;
DR   B1IG08, GLMM_CLOBK ;  A7GJ15, GLMM_CLOBL ;  B1KSG4, GLMM_CLOBM ;
DR   B8I0I6, GLMM_CLOCE ;  Q18CL0, GLMM_CLOD6 ;  B9DYJ3, GLMM_CLOK1 ;
DR   A5N4Y9, GLMM_CLOK5 ;  A0PXZ6, GLMM_CLONN ;  Q0TMX1, GLMM_CLOP1 ;
DR   Q8XHZ5, GLMM_CLOPE ;  A9KSW8, GLMM_CLOPH ;  Q0SQL7, GLMM_CLOPS ;
DR   Q890U1, GLMM_CLOTE ;  A3DEL6, GLMM_CLOTH ;  Q47YJ7, GLMM_COLP3 ;
DR   C3PL50, GLMM_CORA7 ;  Q6NJ50, GLMM_CORDI ;  Q8FS18, GLMM_COREF ;
DR   A4QBS5, GLMM_CORGB ;  Q8NST4, GLMM_CORGL ;  Q4JTD7, GLMM_CORJK ;
DR   B1VEZ9, GLMM_CORU7 ;  B6J7Z9, GLMM_COXB1 ;  B6IZD8, GLMM_COXB2 ;
DR   A9KGE3, GLMM_COXBN ;  A9N8M1, GLMM_COXBR ;  Q83BY7, GLMM_COXBU ;
DR   Q0K8Y7, GLMM_CUPNH ;  Q46ZA1, GLMM_CUPPJ ;  B3R1R9, GLMM_CUPTR ;
DR   B1WR00, GLMM_CYAA5 ;  B7KL75, GLMM_CYAP7 ;  B7JYN0, GLMM_CYAP8 ;
DR   Q47HH9, GLMM_DECAR ;  C1CWA3, GLMM_DEIDV ;  Q1IXS5, GLMM_DEIGD ;
DR   Q9RSQ3, GLMM_DEIRA ;  A9BMK7, GLMM_DELAS ;  C6BTS9, GLMM_DESAD ;
DR   C0QGV9, GLMM_DESAH ;  B1I1Y5, GLMM_DESAP ;  B8J1K3, GLMM_DESDA ;
DR   Q311T0, GLMM_DESDG ;  Q24NW7, GLMM_DESHY ;  C4XU39, GLMM_DESMR ;
DR   Q6AMQ5, GLMM_DESPS ;  A4J190, GLMM_DESRM ;  Q72CK1, GLMM_DESVH ;
DR   B8DN76, GLMM_DESVM ;  A1VED4, GLMM_DESVV ;  A5EUT6, GLMM_DICNV ;
DR   B5YDY1, GLMM_DICT6 ;  B8E222, GLMM_DICTD ;  A8LS40, GLMM_DINSH ;
DR   A7ZS72, GLMM_ECO24 ;  B7UJ69, GLMM_ECO27 ;  B7MB95, GLMM_ECO45 ;
DR   B7LHN9, GLMM_ECO55 ;  Q8X9L2, GLMM_ECO57 ;  B5YS65, GLMM_ECO5E ;
DR   B7NKP3, GLMM_ECO7I ;  B7N0V9, GLMM_ECO81 ;  B7M082, GLMM_ECO8A ;
DR   C4ZSR5, GLMM_ECOBW ;  B1XGY6, GLMM_ECODH ;  A8A4Z0, GLMM_ECOHS ;
DR   A1AG79, GLMM_ECOK1 ;  Q0TCT4, GLMM_ECOL5 ;  Q8FD84, GLMM_ECOL6 ;
DR   B1IQU7, GLMM_ECOLC ;  P31120, GLMM_ECOLI ;  B7NDG0, GLMM_ECOLU ;
DR   B6I1P9, GLMM_ECOSE ;  B1LFS6, GLMM_ECOSM ;  Q1R6G2, GLMM_ECOUT ;
DR   C5BFB3, GLMM_EDWI9 ;  A4WEY7, GLMM_ENT38 ;  A7MIM5, GLMM_ENTS8 ;
DR   Q6D9B6, GLMM_ERWCT ;  B2VGT8, GLMM_ERWT9 ;  Q2N850, GLMM_ERYLH ;
DR   B7LR43, GLMM_ESCF3 ;  C4Z1Z8, GLMM_EUBE2 ;  B1YH95, GLMM_EXIS2 ;
DR   C4KZK4, GLMM_EXISA ;  B0S2Q1, GLMM_FINM2 ;  Q0RRN7, GLMM_FRAAA ;
DR   B0TWU1, GLMM_FRAP2 ;  Q2JFE2, GLMM_FRASC ;  A8LAZ9, GLMM_FRASN ;
DR   Q14JZ1, GLMM_FRAT1 ;  A7NEF9, GLMM_FRATF ;  Q2A1J6, GLMM_FRATH ;
DR   B2SEZ6, GLMM_FRATM ;  A0Q8C5, GLMM_FRATN ;  Q0BK99, GLMM_FRATO ;
DR   Q5NII8, GLMM_FRATT ;  A4IW39, GLMM_FRATW ;  Q8R6A7, GLMM_FUSNN ;
DR   B5EHA7, GLMM_GEOBB ;  Q5L3P1, GLMM_GEOKA ;  B3E692, GLMM_GEOLS ;
DR   Q39UF9, GLMM_GEOMG ;  B9M5K3, GLMM_GEOSF ;  Q74C70, GLMM_GEOSL ;
DR   C6E5P5, GLMM_GEOSM ;  A4IJN4, GLMM_GEOTN ;  A5G536, GLMM_GEOUR ;
DR   A9HB20, GLMM_GLUDA ;  Q5FQB4, GLMM_GLUOX ;  Q0BT42, GLMM_GRABC ;
DR   Q7VP94, GLMM_HAEDU ;  Q4QKI9, GLMM_HAEI8 ;  A5UC76, GLMM_HAEIE ;
DR   P45164, GLMM_HAEIN ;  B8F5R2, GLMM_HAEPS ;  Q0I2Q5, GLMM_HAES1 ;
DR   B0UTS2, GLMM_HAES2 ;  Q2SML8, GLMM_HAHCH ;  A1WXX0, GLMM_HALHL ;
DR   B8D0U9, GLMM_HALOH ;  C4K7K5, GLMM_HAMD5 ;  Q17VS9, GLMM_HELAH ;
DR   Q7VF98, GLMM_HELHP ;  B0TCS1, GLMM_HELMI ;  B6JPH8, GLMM_HELP2 ;
DR   B5Z677, GLMM_HELPG ;  Q1CV79, GLMM_HELPH ;  Q9ZMZ2, GLMM_HELPJ ;
DR   B2UW73, GLMM_HELPS ;  P25177, GLMM_HELPY ;  A4G4B3, GLMM_HERAR ;
DR   Q0C5U1, GLMM_HYPNA ;  Q5R0R2, GLMM_IDILO ;  A6T078, GLMM_JANMA ;
DR   Q28NS0, GLMM_JANSC ;  A6W5X2, GLMM_KINRD ;  B5XSW5, GLMM_KLEP3 ;
DR   A6TEJ5, GLMM_KLEP7 ;  B2GJ26, GLMM_KOCRD ;  Q5FL35, GLMM_LACAC ;
DR   Q03SJ3, GLMM_LACBA ;  Q03AF8, GLMM_LACC3 ;  B3WD16, GLMM_LACCB ;
DR   Q1GB12, GLMM_LACDA ;  Q04BF6, GLMM_LACDB ;  B2GAN5, GLMM_LACF3 ;
DR   Q042H3, GLMM_LACGA ;  A8YUF8, GLMM_LACH4 ;  Q74K59, GLMM_LACJO ;
DR   Q9CID9, GLMM_LACLA ;  A2RIG0, GLMM_LACLM ;  Q031P2, GLMM_LACLS ;
DR   Q88YE8, GLMM_LACPL ;  A5VIK4, GLMM_LACRD ;  B2G638, GLMM_LACRJ ;
DR   Q1WSZ9, GLMM_LACS1 ;  Q38VX2, GLMM_LACSS ;  Q1MRX8, GLMM_LAWIP ;
DR   Q5X1A3, GLMM_LEGPA ;  A5IHW7, GLMM_LEGPC ;  Q5ZRT4, GLMM_LEGPH ;
DR   Q5WT16, GLMM_LEGPL ;  Q6AD28, GLMM_LEIXX ;  B1XXG0, GLMM_LEPCP ;
DR   B1N017, GLMM_LEUCK ;  Q03VW4, GLMM_LEUMM ;  Q929Q1, GLMM_LISIN ;
DR   Q71XP5, GLMM_LISMF ;  Q8Y5E6, GLMM_LISMO ;  A0AKM3, GLMM_LISW6 ;
DR   B1HMT3, GLMM_LYSSC ;  B9E9W9, GLMM_MACCJ ;  Q2W2C2, GLMM_MAGSA ;
DR   A0L4J3, GLMM_MAGSM ;  Q65TY6, GLMM_MANSM ;  A1U605, GLMM_MARAV ;
DR   Q0ALR7, GLMM_MARMM ;  A6VU24, GLMM_MARMS ;  Q11DI7, GLMM_MESSB ;
DR   A6UU47, GLMM_META3 ;  Q8TLL2, GLMM_METAC ;  Q46AY7, GLMM_METBF ;
DR   Q12TN0, GLMM_METBU ;  B7KWJ1, GLMM_METC4 ;  Q607B4, GLMM_METCA ;
DR   A9W9G7, GLMM_METEP ;  Q1H384, GLMM_METFK ;  Q58500, GLMM_METJA ;
DR   Q8TWY8, GLMM_METKA ;  A4FX97, GLMM_METM5 ;  A6VG24, GLMM_METM7 ;
DR   Q8Q037, GLMM_METMA ;  Q6LYB4, GLMM_METMP ;  B8ID24, GLMM_METNO ;
DR   B1ZBR8, GLMM_METPB ;  A2SF93, GLMM_METPP ;  B1M3G3, GLMM_METRJ ;
DR   A5UKY3, GLMM_METS3 ;  B0ULF6, GLMM_METS4 ;  B8ER03, GLMM_METSB ;
DR   Q2NES6, GLMM_METST ;  O27627, GLMM_METTH ;  A6UP86, GLMM_METVS ;
DR   B0JVZ6, GLMM_MICAN ;  Q2RGA6, GLMM_MOOTA ;  A0QKT1, GLMM_MYCA1 ;
DR   Q7TWH9, GLMM_MYCBO ;  A1KPC8, GLMM_MYCBP ;  C1AHQ0, GLMM_MYCBT ;
DR   A4TEL0, GLMM_MYCGI ;  B8ZUC1, GLMM_MYCLB ;  Q49869, GLMM_MYCLE ;
DR   B2HCZ2, GLMM_MYCMM ;  Q73S29, GLMM_MYCPA ;  A0QSQ1, GLMM_MYCS2 ;
DR   A3PVN7, GLMM_MYCSJ ;  A1UC06, GLMM_MYCSK ;  Q1BCY7, GLMM_MYCSS ;
DR   A5U8B7, GLMM_MYCTA ;  O06258, GLMM_MYCTU ;  A0PMD3, GLMM_MYCUA ;
DR   A1T554, GLMM_MYCVP ;  Q1D498, GLMM_MYXXD ;  B2A4R9, GLMM_NATTJ ;
DR   B9L5Z7, GLMM_NAUPA ;  Q5F746, GLMM_NEIG1 ;  A9M1R2, GLMM_NEIM0 ;
DR   Q9JT71, GLMM_NEIMA ;  Q9JY89, GLMM_NEIMB ;  A1KV99, GLMM_NEIMF ;
DR   Q70GH6, GLMM_NEISU ;  Q0AHC3, GLMM_NITEC ;  Q82WX6, GLMM_NITEU ;
DR   Q1QP86, GLMM_NITHX ;  Q2YBS8, GLMM_NITMU ;  Q3J826, GLMM_NITOC ;
DR   A6Q164, GLMM_NITSB ;  Q3SNB8, GLMM_NITWN ;  Q5Z1H8, GLMM_NOCFA ;
DR   A1SF29, GLMM_NOCSJ ;  B2J997, GLMM_NOSP7 ;  Q8YVS4, GLMM_NOSS1 ;
DR   Q2GB44, GLMM_NOVAD ;  Q8ETM7, GLMM_OCEIH ;  A6WY87, GLMM_OCHA4 ;
DR   B6JIL2, GLMM_OLICO ;  A1AZG3, GLMM_PARDP ;  A7HV12, GLMM_PARL1 ;
DR   Q6MBL8, GLMM_PARUW ;  Q9CNJ0, GLMM_PASMU ;  C6DKI6, GLMM_PECCP ;
DR   Q03GV0, GLMM_PEDPA ;  Q3A5V5, GLMM_PELCD ;  A1AR93, GLMM_PELPD ;
DR   A5D4W7, GLMM_PELTS ;  Q4FN15, GLMM_PELUB ;  B4R906, GLMM_PHEZH ;
DR   Q7MYY3, GLMM_PHOLL ;  Q6LUJ6, GLMM_PHOPR ;  A1VQI3, GLMM_POLNA ;
DR   Q129M7, GLMM_POLSJ ;  A4SXL3, GLMM_POLSQ ;  Q6A6T5, GLMM_PROAC ;
DR   A3PAW2, GLMM_PROM0 ;  A8G2Q0, GLMM_PROM2 ;  A2CCG3, GLMM_PROM3 ;
DR   A2BUM2, GLMM_PROM5 ;  Q31CU1, GLMM_PROM9 ;  Q7VDU7, GLMM_PROMA ;
DR   B4F2B5, GLMM_PROMH ;  Q7V4W4, GLMM_PROMM ;  Q7V349, GLMM_PROMP ;
DR   A2BP40, GLMM_PROMS ;  Q48E72, GLMM_PSE14 ;  Q15VJ3, GLMM_PSEA6 ;
DR   A6VCK6, GLMM_PSEA7 ;  B7V1G1, GLMM_PSEA8 ;  Q02FS3, GLMM_PSEAB ;
DR   Q9HV50, GLMM_PSEAE ;  Q1IF48, GLMM_PSEE4 ;  Q4KIG0, GLMM_PSEF5 ;
DR   C3K264, GLMM_PSEFS ;  Q3IE61, GLMM_PSEHT ;  A4XYE5, GLMM_PSEMY ;
DR   A5W992, GLMM_PSEP1 ;  Q3KI89, GLMM_PSEPF ;  B0KHY3, GLMM_PSEPG ;
DR   Q88DV3, GLMM_PSEPK ;  B1J265, GLMM_PSEPW ;  Q87WQ0, GLMM_PSESM ;
DR   P95575, GLMM_PSEU2 ;  A4VPP5, GLMM_PSEU5 ;  Q4FS01, GLMM_PSYA2 ;
DR   Q1QC16, GLMM_PSYCK ;  A1ST41, GLMM_PSYIN ;  A5WEW6, GLMM_PSYWF ;
DR   Q9UZT5, GLMM_PYRAB ;  Q8U2H4, GLMM_PYRFU ;  O58973, GLMM_PYRHO ;
DR   Q68BJ7, GLMM_PYRKO ;  Q1LLB1, GLMM_RALME ;  B2UGP7, GLMM_RALPJ ;
DR   Q8XZ76, GLMM_RALSO ;  A9WMF8, GLMM_RENSM ;  B3PYX0, GLMM_RHIE6 ;
DR   Q2K4M3, GLMM_RHIEC ;  Q1MC77, GLMM_RHIL3 ;  Q98F91, GLMM_RHILO ;
DR   B5ZNL4, GLMM_RHILW ;  Q92M99, GLMM_RHIME ;  B6ITH3, GLMM_RHOCS ;
DR   C0ZW79, GLMM_RHOE4 ;  Q21WW5, GLMM_RHOFD ;  C1B058, GLMM_RHOOB ;
DR   Q2J0J3, GLMM_RHOP2 ;  Q07IZ1, GLMM_RHOP5 ;  Q6N1T6, GLMM_RHOPA ;
DR   Q20YZ7, GLMM_RHOPB ;  Q131V4, GLMM_RHOPS ;  B3Q6Y9, GLMM_RHOPT ;
DR   Q2RVE4, GLMM_RHORT ;  A3PH12, GLMM_RHOS1 ;  Q3J5C2, GLMM_RHOS4 ;
DR   A4WQ91, GLMM_RHOS5 ;  B9KM35, GLMM_RHOSK ;  Q0S3D6, GLMM_RHOSR ;
DR   Q168N3, GLMM_ROSDO ;  Q1AU65, GLMM_RUBXD ;  A1AVH5, GLMM_RUTMC ;
DR   Q21H51, GLMM_SACD2 ;  A4FPG9, GLMM_SACEN ;  B5F6U4, GLMM_SALA4 ;
DR   A8M4B8, GLMM_SALAI ;  A9MP31, GLMM_SALAR ;  Q57JH3, GLMM_SALCH ;
DR   B5FI19, GLMM_SALDC ;  B5QZW4, GLMM_SALEP ;  B5REP2, GLMM_SALG2 ;
DR   B4TJ12, GLMM_SALHS ;  B4T705, GLMM_SALNS ;  Q5PLC4, GLMM_SALPA ;
DR   A9N740, GLMM_SALPB ;  C0PZ59, GLMM_SALPC ;  B5BGK0, GLMM_SALPK ;
DR   B4TWE3, GLMM_SALSV ;  Q8XF81, GLMM_SALTI ;  A4XBI5, GLMM_SALTO ;
DR   Q7CPP9, GLMM_SALTY ;  A8G903, GLMM_SERP5 ;  A3D7L1, GLMM_SHEB5 ;
DR   Q12QI6, GLMM_SHEDO ;  B0TQA7, GLMM_SHEHH ;  A3QGV0, GLMM_SHELP ;
DR   Q8EHM0, GLMM_SHEON ;  A8H745, GLMM_SHEPA ;  A4Y9C5, GLMM_SHEPC ;
DR   B8CKG8, GLMM_SHEPW ;  A0KTZ1, GLMM_SHESA ;  A8FYS5, GLMM_SHESH ;
DR   A1RGX0, GLMM_SHESW ;  B2U201, GLMM_SHIB3 ;  Q31W53, GLMM_SHIBS ;
DR   Q32BF7, GLMM_SHIDS ;  Q0T0A8, GLMM_SHIF8 ;  Q83Q15, GLMM_SHIFL ;
DR   Q3YX65, GLMM_SHISS ;  Q5LTP9, GLMM_SILPO ;  Q1GE79, GLMM_SILST ;
DR   A6UCS2, GLMM_SINMW ;  Q2NW27, GLMM_SODGM ;  Q027B2, GLMM_SOLUE ;
DR   A9G862, GLMM_SORC5 ;  Q1GUJ4, GLMM_SPHAL ;  A5V2D8, GLMM_SPHWW ;
DR   A7X524, GLMM_STAA1 ;  A6U3P1, GLMM_STAA2 ;  Q2FEX1, GLMM_STAA3 ;
DR   P0C0V7, GLMM_STAA8 ;  A5IUV1, GLMM_STAA9 ;  Q2YYE6, GLMM_STAAB ;
DR   Q5HE43, GLMM_STAAC ;  A6QJ02, GLMM_STAAE ;  P65704, GLMM_STAAM ;
DR   P99087, GLMM_STAAN ;  Q6GER6, GLMM_STAAR ;  Q6G7F2, GLMM_STAAS ;
DR   A8YYC6, GLMM_STAAT ;  P65705, GLMM_STAAW ;  B9DM98, GLMM_STACT ;
DR   Q5HM67, GLMM_STAEQ ;  Q8CNH0, GLMM_STAES ;  Q4L837, GLMM_STAHJ ;
DR   Q49ZA7, GLMM_STAS1 ;  Q3K1H1, GLMM_STRA1 ;  Q8E5S6, GLMM_STRA3 ;
DR   Q8E049, GLMM_STRA5 ;  Q82DL7, GLMM_STRAW ;  Q53876, GLMM_STRCO ;
DR   C0M9C4, GLMM_STRE4 ;  B4U3I6, GLMM_STREM ;  A8AWM5, GLMM_STRGC ;
DR   B1W3X3, GLMM_STRGG ;  B4SQU4, GLMM_STRM5 ;  B2FNY7, GLMM_STRMK ;
DR   Q8DTC6, GLMM_STRMU ;  Q99ZW8, GLMM_STRP1 ;  Q04JI8, GLMM_STRP2 ;
DR   P0DB38, GLMM_STRP3 ;  B5E6K3, GLMM_STRP4 ;  Q5XCE0, GLMM_STRP6 ;
DR   C1C8F1, GLMM_STRP7 ;  Q8P179, GLMM_STRP8 ;  Q1JC19, GLMM_STRPB ;
DR   Q1JM03, GLMM_STRPC ;  Q1JH49, GLMM_STRPD ;  Q1J6W8, GLMM_STRPF ;
DR   A2REP8, GLMM_STRPG ;  B1ICY0, GLMM_STRPI ;  B8ZLM2, GLMM_STRPJ ;
DR   Q48TV1, GLMM_STRPM ;  Q97PP4, GLMM_STRPN ;  P0DB39, GLMM_STRPQ ;
DR   B2IR78, GLMM_STRPS ;  Q8DP16, GLMM_STRR6 ;  A4W2Q0, GLMM_STRS2 ;
DR   C0MDT1, GLMM_STRS7 ;  A3CM30, GLMM_STRSV ;  A4VWE5, GLMM_STRSY ;
DR   Q5LZA7, GLMM_STRT1 ;  Q5M3V8, GLMM_STRT2 ;  Q03K54, GLMM_STRTD ;
DR   B9DSE8, GLMM_STRU0 ;  C1CFE3, GLMM_STRZJ ;  C1CLQ9, GLMM_STRZP ;
DR   C1CSI0, GLMM_STRZT ;  Q30NW8, GLMM_SULDN ;  A6Q6B6, GLMM_SULNB ;
DR   Q67T14, GLMM_SYMTH ;  Q2LRC1, GLMM_SYNAS ;  Q31LA7, GLMM_SYNE7 ;
DR   A0LMD8, GLMM_SYNFM ;  B1XP15, GLMM_SYNP2 ;  Q5N0M0, GLMM_SYNP6 ;
DR   A5GII9, GLMM_SYNPW ;  Q7U9H6, GLMM_SYNPX ;  A5GW63, GLMM_SYNR3 ;
DR   Q0IDB3, GLMM_SYNS3 ;  Q3AW32, GLMM_SYNS9 ;  Q3AMX9, GLMM_SYNSC ;
DR   Q0AV62, GLMM_SYNWW ;  P73648, GLMM_SYNY3 ;  C5BQ00, GLMM_TERTT ;
DR   B7IDU4, GLMM_THEAB ;  Q8DI20, GLMM_THEEB ;  Q47LM7, GLMM_THEFY ;
DR   C5A2H8, GLMM_THEGJ ;  A6LMW5, GLMM_THEM4 ;  Q9WY28, GLMM_THEMA ;
DR   B9K6U6, GLMM_THENN ;  B6YXX2, GLMM_THEON ;  A5IKN6, GLMM_THEP1 ;
DR   B0KD39, GLMM_THEP3 ;  B0K5X4, GLMM_THEPX ;  B1L9W8, GLMM_THESQ ;
DR   Q72JS7, GLMM_THET2 ;  Q5SMH2, GLMM_THET8 ;  Q8R840, GLMM_THETN ;
DR   B5YGX0, GLMM_THEYD ;  Q31HG3, GLMM_THICR ;  Q3SJR2, GLMM_THIDA ;
DR   B8GNY2, GLMM_THISH ;  Q116W4, GLMM_TRIEI ;  Q83NS5, GLMM_TROW8 ;
DR   Q83GU5, GLMM_TROWT ;  Q0W4I8, GLMM_UNCMA ;  C5CKU7, GLMM_VARPS ;
DR   A1WEE4, GLMM_VEREI ;  A5CXP9, GLMM_VESOH ;  A5F930, GLMM_VIBC3 ;
DR   Q9KU84, GLMM_VIBCH ;  C3LSP4, GLMM_VIBCM ;  Q5E7M0, GLMM_VIBF1 ;
DR   B5FA75, GLMM_VIBFM ;  A7MUV2, GLMM_VIBHB ;  Q87LZ7, GLMM_VIBPA ;
DR   B7VJI1, GLMM_VIBSL ;  Q8DBW4, GLMM_VIBVU ;  Q7MI04, GLMM_VIBVY ;
DR   Q8D2X3, GLMM_WIGBR ;  Q7M9M2, GLMM_WOLSU ;  Q8PJ31, GLMM_XANAC ;
DR   Q3BRL9, GLMM_XANC5 ;  Q4UWC8, GLMM_XANC8 ;  B0RR88, GLMM_XANCB ;
DR   Q8P7S2, GLMM_XANCP ;  Q2P0U5, GLMM_XANOM ;  B2SVN3, GLMM_XANOP ;
DR   Q5GXR8, GLMM_XANOR ;  A7IIG5, GLMM_XANP2 ;  B2IA03, GLMM_XYLF2 ;
DR   Q9PDB1, GLMM_XYLFA ;  B0U6T2, GLMM_XYLFM ;  Q87DJ6, GLMM_XYLFT ;
DR   A1JIW5, GLMM_YERE8 ;  A7FMS6, GLMM_YERP3 ;  Q1CC03, GLMM_YERPA ;
DR   B2K2Q1, GLMM_YERPB ;  Q8ZBB8, GLMM_YERPE ;  A9R599, GLMM_YERPG ;
DR   Q1CEK9, GLMM_YERPN ;  A4TRI7, GLMM_YERPP ;  Q66F64, GLMM_YERPS ;
DR   B1JMH4, GLMM_YERPY ;  Q5NNT4, GLMM_ZYMMO ;
//
ID   5.4.3.1
DE   Deleted entry.
//
ID   5.4.3.2
DE   Lysine 2,3-aminomutase.
CA   L-lysine = (3S)-3,6-diaminohexanoate.
CC   -!- Activity is stimulated by S-adenosyl-L-methionine and pyridoxal
CC       phosphate.
DR   O34676, KAMA_BACSU ;  Q9XBQ8, KAMA_CLOSU ;
//
ID   5.4.3.3
DE   Beta-lysine 5,6-aminomutase.
AN   Beta-lysine mutase.
CA   (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate.
CF   Cobalamin.
//
ID   5.4.3.4
DE   D-lysine 5,6-aminomutase.
AN   Adenosylcobalamin-dependent D-lysine 5,6-aminomutase.
AN   D-alpha-lysine mutase.
CA   D-lysine = 2,5-diaminohexanoate.
CF   Cobalamin.
//
ID   5.4.3.5
DE   D-ornithine 4,5-aminomutase.
AN   D-alpha-ornithine 5,4-aminomutase.
AN   D-ornithine aminomutase.
CA   D-ornithine = (2R,4S)-2,4-diaminopentanoate.
CF   Cobalamin; Pyridoxal 5'-phosphate.
//
ID   5.4.3.6
DE   Tyrosine 2,3-aminomutase.
AN   Tyrosine alpha,beta-mutase.
CA   L-tyrosine = 3-amino-3-(4-hydroxyphenyl)propanoate.
CF   MIO.
DR   Q1LRV9, TALY_RALME ;  Q0VZ68, TAM_CHOCO  ;  B8ZV93, TAM_MYXFU  ;
DR   B8ZV94, TAM_MYXSM  ;
//
ID   5.4.3.7
DE   Leucine 2,3-aminomutase.
CA   (2S)-alpha-leucine = (3R)-beta-leucine.
CF   Cobalamin.
//
ID   5.4.3.8
DE   Glutamate-1-semialdehyde 2,1-aminomutase.
AN   Glutamate-1-semialdehyde aminotransferase.
CA   (S)-4-amino-5-oxopentanoate = 5-aminolevulinate.
PR   PROSITE; PDOC00519;
DR   B7GIK0, GSA1_ANOFW ;  P42799, GSA1_ARATH ;  A7Z2N8, GSA1_BACA2 ;
DR   C3PCZ3, GSA1_BACAA ;  C3LHA0, GSA1_BACAC ;  A0R9G6, GSA1_BACAH ;
DR   Q81YV0, GSA1_BACAN ;  B7JNG6, GSA1_BACC0 ;  Q73DX4, GSA1_BACC1 ;
DR   B7IIX2, GSA1_BACC2 ;  C1EWG6, GSA1_BACC3 ;  B7H9S6, GSA1_BACC4 ;
DR   B7HU66, GSA1_BACC7 ;  A7GL00, GSA1_BACCN ;  B9J3N2, GSA1_BACCQ ;
DR   Q81I85, GSA1_BACCR ;  Q63GB4, GSA1_BACCZ ;  Q9KEB0, GSA1_BACHD ;
DR   Q6HNS8, GSA1_BACHK ;  Q65M82, GSA1_BACLD ;  A8FB92, GSA1_BACP2 ;
DR   Q5WIE9, GSA1_BACSK ;  A9VSS7, GSA1_BACWK ;  C0Z671, GSA1_BREBN ;
DR   A0RXB3, GSA1_CENSY ;  A9KP86, GSA1_CLOPH ;  B1YK58, GSA1_EXIS2 ;
DR   C4L367, GSA1_EXISA ;  Q5L2S4, GSA1_GEOKA ;  A4IKL1, GSA1_GEOTN ;
DR   Q92BG1, GSA1_LISIN ;  C1KVK0, GSA1_LISMC ;  Q71ZB5, GSA1_LISMF ;
DR   B8DFN7, GSA1_LISMH ;  Q8Y6X8, GSA1_LISMO ;  A0AJ02, GSA1_LISW6 ;
DR   B1HUT1, GSA1_LYSSC ;  B9E740, GSA1_MACCJ ;  Q8CV56, GSA1_OCEIH ;
DR   A7X388, GSA1_STAA1 ;  A6U2D5, GSA1_STAA2 ;  Q2FG69, GSA1_STAA3 ;
DR   Q2FXR4, GSA1_STAA8 ;  A5ITJ2, GSA1_STAA9 ;  Q2YTC2, GSA1_STAAB ;
DR   Q5HFA5, GSA1_STAAC ;  A6QHK1, GSA1_STAAE ;  P63508, GSA1_STAAM ;
DR   P99096, GSA1_STAAN ;  Q6GG38, GSA1_STAAR ;  Q6G8Q8, GSA1_STAAS ;
DR   A8Z2I8, GSA1_STAAT ;  P0C1P8, GSA1_STAAU ;  Q8NW75, GSA1_STAAW ;
DR   B9DND8, GSA1_STACT ;  Q5HNN6, GSA1_STAEQ ;  Q8CNZ1, GSA1_STAES ;
DR   Q4L7G9, GSA1_STAHJ ;  Q49YQ9, GSA1_STAS1 ;  B7GH35, GSA2_ANOFW ;
DR   Q42522, GSA2_ARATH ;  A7Z7A2, GSA2_BACA2 ;  C3P9E6, GSA2_BACAA ;
DR   C3L6Z2, GSA2_BACAC ;  A0RJ78, GSA2_BACAH ;  Q81LD0, GSA2_BACAN ;
DR   B7JQ54, GSA2_BACC0 ;  Q72ZW5, GSA2_BACC1 ;  B7IW22, GSA2_BACC2 ;
DR   C1ETQ7, GSA2_BACC3 ;  B7HE93, GSA2_BACC4 ;  B7HQM1, GSA2_BACC7 ;
DR   A7GTE2, GSA2_BACCN ;  B9IZ36, GSA2_BACCQ ;  Q817R3, GSA2_BACCR ;
DR   Q633Y3, GSA2_BACCZ ;  Q9K8G3, GSA2_BACHD ;  Q6HD65, GSA2_BACHK ;
DR   Q65GK4, GSA2_BACLD ;  A8FFU9, GSA2_BACP2 ;  Q5WEP8, GSA2_BACSK ;
DR   A9VIT5, GSA2_BACWK ;  C0ZAH4, GSA2_BREBN ;  O74038, GSA2_CENSY ;
DR   A9KSC7, GSA2_CLOPH ;  B1YJU8, GSA2_EXIS2 ;  C4L4J9, GSA2_EXISA ;
DR   Q5KWK9, GSA2_GEOKA ;  A4IRG2, GSA2_GEOTN ;  Q92AX5, GSA2_LISIN ;
DR   C1KVY4, GSA2_LISMC ;  Q71YY2, GSA2_LISMF ;  B8DHJ5, GSA2_LISMH ;
DR   Q8Y6J9, GSA2_LISMO ;  A0AJD9, GSA2_LISW6 ;  B1HVD3, GSA2_LYSSC ;
DR   B9E7Y3, GSA2_MACCJ ;  Q8CZE3, GSA2_OCEIH ;  A7X3X9, GSA2_STAA1 ;
DR   A6U2W8, GSA2_STAA2 ;  Q2FFN1, GSA2_STAA3 ;  Q2G283, GSA2_STAA8 ;
DR   A5IU30, GSA2_STAA9 ;  Q2YU22, GSA2_STAAB ;  Q5HER0, GSA2_STAAC ;
DR   A6QI46, GSA2_STAAE ;  Q99T15, GSA2_STAAM ;  Q7A4T5, GSA2_STAAN ;
DR   Q6GFJ3, GSA2_STAAR ;  Q6G870, GSA2_STAAS ;  A8YY36, GSA2_STAAT ;
DR   Q8NVU6, GSA2_STAAW ;  B9DMX3, GSA2_STACT ;  Q5HN71, GSA2_STAEQ ;
DR   Q8CRW7, GSA2_STAES ;  Q4L706, GSA2_STAHJ ;  Q49Y99, GSA2_STAS1 ;
DR   P71084, GSAB_BACSU ;  B0CC57, GSA_ACAM1  ;  A1TKK8, GSA_ACIAC  ;
DR   Q6FCY1, GSA_ACIAD  ;  B7GYZ5, GSA_ACIB3  ;  B7I4N4, GSA_ACIB5  ;
DR   B2HW19, GSA_ACIBC  ;  Q1IHV2, GSA_ACIBL  ;  B0VU92, GSA_ACIBS  ;
DR   A3M7I8, GSA_ACIBT  ;  B0VCN6, GSA_ACIBY  ;  A0LRE5, GSA_ACIC1  ;
DR   C1F911, GSA_ACIC5  ;  B9MF68, GSA_ACIET  ;  B7JBI1, GSA_ACIF2  ;
DR   B5ERN9, GSA_ACIF5  ;  A1WBR8, GSA_ACISJ  ;  A3N2K3, GSA_ACTP2  ;
DR   B3GYN8, GSA_ACTP7  ;  B0BRF0, GSA_ACTPJ  ;  A6VQ66, GSA_ACTSZ  ;
DR   A0KNY9, GSA_AERHH  ;  Q9Y9I9, GSA_AERPE  ;  A4SJ79, GSA_AERS4  ;
DR   B2UNE3, GSA_AKKM8  ;  Q0VSP6, GSA_ALCBS  ;  Q0AAH7, GSA_ALHEH  ;
DR   B6EL04, GSA_ALISL  ;  A6TJD8, GSA_ALKMQ  ;  A8MGY8, GSA_ALKOO  ;
DR   B4S0D0, GSA_ALTMD  ;  B8JCU6, GSA_ANAD2  ;  Q2IHP8, GSA_ANADE  ;
DR   A7HIX3, GSA_ANADF  ;  B4UKE6, GSA_ANASK  ;  B9MRJ7, GSA_ANATD  ;
DR   Q3M3B9, GSA_ANAVT  ;  O66998, GSA_AQUAE  ;  A8ETJ2, GSA_ARCB4  ;
DR   O29027, GSA_ARCFU  ;  Q5P6J6, GSA_AROAE  ;  A1R898, GSA_ARTAT  ;
DR   B8HBR2, GSA_ARTCA  ;  A0JYM2, GSA_ARTS2  ;  A1KB59, GSA_AZOSB  ;
DR   C1DMY5, GSA_AZOVD  ;  P30949, GSA_BACSU  ;  Q6MHT9, GSA_BDEBA  ;
DR   Q2KUS4, GSA_BORA1  ;  Q7WF71, GSA_BORBR  ;  Q7W3U1, GSA_BORPA  ;
DR   A9I1R3, GSA_BORPD  ;  Q7W050, GSA_BORPE  ;  Q85WB7, GSA_BRANA  ;
DR   B1YUJ7, GSA_BURA4  ;  Q1BYB1, GSA_BURCA  ;  B1JX81, GSA_BURCC  ;
DR   A0K5D7, GSA_BURCH  ;  B4EBT3, GSA_BURCJ  ;  Q0BHJ2, GSA_BURCM  ;
DR   A9AEU0, GSA_BURM1  ;  A3MMQ8, GSA_BURM7  ;  A2S9D9, GSA_BURM9  ;
DR   Q62HV8, GSA_BURMA  ;  A1V1L0, GSA_BURMS  ;  A3NY82, GSA_BURP0  ;
DR   Q3JPN1, GSA_BURP1  ;  A3NCF3, GSA_BURP6  ;  B2JED5, GSA_BURP8  ;
DR   B2T6C2, GSA_BURPP  ;  Q63RP8, GSA_BURPS  ;  Q39IQ4, GSA_BURS3  ;
DR   Q2SYB2, GSA_BURTA  ;  A4JC86, GSA_BURVG  ;  Q13V40, GSA_BURXL  ;
DR   A8M919, GSA_CALMQ  ;  A4XK09, GSA_CALS8  ;  A7ZCH5, GSA_CAMC1  ;
DR   A7GXK4, GSA_CAMC5  ;  A0RQ51, GSA_CAMFF  ;  A7I252, GSA_CAMHC  ;
DR   A8FLR2, GSA_CAMJ8  ;  A7H3N1, GSA_CAMJD  ;  Q9PP70, GSA_CAMJE  ;
DR   A1VZJ6, GSA_CAMJJ  ;  Q5HUU3, GSA_CAMJR  ;  B9KFS8, GSA_CAMLR  ;
DR   Q3ACS9, GSA_CARHZ  ;  B3PL68, GSA_CELJU  ;  A9WIS7, GSA_CHLAA  ;
DR   Q5L5P0, GSA_CHLAB  ;  B8G822, GSA_CHLAD  ;  Q3AP59, GSA_CHLCH  ;
DR   Q822Q0, GSA_CHLCV  ;  Q254Z2, GSA_CHLFF  ;  B3EI07, GSA_CHLL2  ;
DR   Q9PKI3, GSA_CHLMU  ;  B3QRD2, GSA_CHLP8  ;  B3EKJ7, GSA_CHLPB  ;
DR   A1BJG8, GSA_CHLPD  ;  Q9JRW9, GSA_CHLPN  ;  Q39566, GSA_CHLRE  ;
DR   B9LKS0, GSA_CHLSY  ;  B0B9W0, GSA_CHLT2  ;  B3QSA6, GSA_CHLT3  ;
DR   Q3KMF2, GSA_CHLTA  ;  B0BBJ0, GSA_CHLTB  ;  Q8KAQ7, GSA_CHLTE  ;
DR   O84212, GSA_CHLTR  ;  Q1QSB0, GSA_CHRSD  ;  Q7P1Z5, GSA_CHRVO  ;
DR   A8ALD5, GSA_CITK8  ;  A5CNI7, GSA_CLAM3  ;  B0RBL3, GSA_CLAMS  ;
DR   Q97MU2, GSA_CLOAB  ;  A6LSY8, GSA_CLOB8  ;  B2UX41, GSA_CLOBA  ;
DR   B2TPD4, GSA_CLOBB  ;  B8I0R1, GSA_CLOCE  ;  B9DZG0, GSA_CLOK1  ;
DR   A5N5Y1, GSA_CLOK5  ;  A0Q2A8, GSA_CLONN  ;  Q0TQG7, GSA_CLOP1  ;
DR   P0C2D9, GSA_CLOPE  ;  Q0ST19, GSA_CLOPS  ;  Q897K4, GSA_CLOTE  ;
DR   A3DIF3, GSA_CLOTH  ;  Q47V96, GSA_COLP3  ;  C3PKI4, GSA_CORA7  ;
DR   Q6NJJ2, GSA_CORDI  ;  Q8FSD4, GSA_COREF  ;  A4QB78, GSA_CORGB  ;
DR   Q8NT73, GSA_CORGL  ;  Q4JSY1, GSA_CORJK  ;  B1VEK3, GSA_CORU7  ;
DR   B6J495, GSA_COXB1  ;  B6J3H2, GSA_COXB2  ;  A9KBA0, GSA_COXBN  ;
DR   A9NAX3, GSA_COXBR  ;  Q83AK3, GSA_COXBU  ;  Q0KDN9, GSA_CUPNH  ;
DR   Q46XZ7, GSA_CUPPJ  ;  B3R312, GSA_CUPTR  ;  B1X023, GSA_CYAA5  ;
DR   B8HYK1, GSA_CYAP4  ;  B7KA18, GSA_CYAP7  ;  B7K2I1, GSA_CYAP8  ;
DR   Q11WK1, GSA_CYTH3  ;  Q478V1, GSA_DECAR  ;  C1CWI8, GSA_DEIDV  ;
DR   Q1IWZ8, GSA_DEIGD  ;  Q9RWW0, GSA_DEIRA  ;  A9BY74, GSA_DELAS  ;
DR   B8FBA1, GSA_DESAA  ;  C0QCR9, GSA_DESAH  ;  B1I4L1, GSA_DESAP  ;
DR   B8J3A3, GSA_DESDA  ;  Q30WH2, GSA_DESDG  ;  B8G2L6, GSA_DESHD  ;
DR   Q24VD4, GSA_DESHY  ;  A8ZZU9, GSA_DESOH  ;  Q6AQ32, GSA_DESPS  ;
DR   A4J6H0, GSA_DESRM  ;  Q725I1, GSA_DESVH  ;  B8DN02, GSA_DESVM  ;
DR   A1V9X6, GSA_DESVV  ;  A5EXX1, GSA_DICNV  ;  A7ZHP6, GSA_ECO24  ;
DR   B7UIK1, GSA_ECO27  ;  B7MBD7, GSA_ECO45  ;  B7LGL6, GSA_ECO55  ;
DR   Q8X4V5, GSA_ECO57  ;  B5Z0D4, GSA_ECO5E  ;  B7NIB7, GSA_ECO7I  ;
DR   B7MP16, GSA_ECO81  ;  B7M195, GSA_ECO8A  ;  C4ZRP7, GSA_ECOBW  ;
DR   B1XD24, GSA_ECODH  ;  A7ZWA2, GSA_ECOHS  ;  A1A7K0, GSA_ECOK1  ;
DR   Q0TLH7, GSA_ECOL5  ;  Q8FL16, GSA_ECOL6  ;  B1IQI6, GSA_ECOLC  ;
DR   P23893, GSA_ECOLI  ;  B7N823, GSA_ECOLU  ;  B6HZD0, GSA_ECOSE  ;
DR   B1LGV7, GSA_ECOSM  ;  Q1RG34, GSA_ECOUT  ;  C5BAP9, GSA_EDWI9  ;
DR   A4W6Q1, GSA_ENT38  ;  A7MGR5, GSA_ENTS8  ;  Q6D1Z0, GSA_ERWCT  ;
DR   B2VE25, GSA_ERWT9  ;  B7LWB5, GSA_ESCF3  ;  A5FIM3, GSA_FLAJ1  ;
DR   A6GYW4, GSA_FLAPJ  ;  Q0RS03, GSA_FRAAA  ;  B0U0T6, GSA_FRAP2  ;
DR   Q2JFQ1, GSA_FRASC  ;  A8LCD0, GSA_FRASN  ;  Q14HS1, GSA_FRAT1  ;
DR   A7NCX8, GSA_FRATF  ;  Q2A2U8, GSA_FRATH  ;  B2SGG7, GSA_FRATM  ;
DR   A0Q628, GSA_FRATN  ;  Q0BLC7, GSA_FRATO  ;  Q5NGB9, GSA_FRATT  ;
DR   A4IXN8, GSA_FRATW  ;  Q8RFY7, GSA_FUSNN  ;  C1A7K7, GSA_GEMAT  ;
DR   B5EFG4, GSA_GEOBB  ;  B3E9X0, GSA_GEOLS  ;  Q39QA6, GSA_GEOMG  ;
DR   B9LZL6, GSA_GEOSF  ;  Q74GA9, GSA_GEOSL  ;  A5G9C0, GSA_GEOUR  ;
DR   Q7NPI4, GSA_GLOVI  ;  A0LXY3, GSA_GRAFK  ;  B8F7H5, GSA_HAEPS  ;
DR   Q0I3R7, GSA_HAES1  ;  B0UST3, GSA_HAES2  ;  Q2S8X9, GSA_HAHCH  ;
DR   A1WYL3, GSA_HALHL  ;  B9LTZ9, GSA_HALLT  ;  Q5UZ90, GSA_HALMA  ;
DR   B0R7L9, GSA_HALS3  ;  Q9HMY8, GSA_HALSA  ;  Q18ES5, GSA_HALWD  ;
DR   C4K6Y5, GSA_HAMD5  ;  Q17X40, GSA_HELAH  ;  Q7VHK3, GSA_HELHP  ;
DR   B0TFV0, GSA_HELMI  ;  B6JKN5, GSA_HELP2  ;  B5ZA72, GSA_HELPG  ;
DR   Q1CUJ7, GSA_HELPH  ;  Q9ZMD0, GSA_HELPJ  ;  B2USD7, GSA_HELPS  ;
DR   P56115, GSA_HELPY  ;  A9B550, GSA_HERA2  ;  A4G8N0, GSA_HERAR  ;
DR   P18492, GSA_HORVU  ;  B4U8M6, GSA_HYDS0  ;  A2BL27, GSA_HYPBU  ;
DR   Q5QVP9, GSA_IDILO  ;  A8AAB3, GSA_IGNH4  ;  A6T2A2, GSA_JANMA  ;
DR   A6W5M6, GSA_KINRD  ;  B5Y1L5, GSA_KLEP3  ;  A6T4V8, GSA_KLEP7  ;
DR   B2GL27, GSA_KOCRD  ;  A5VM65, GSA_LACRD  ;  B2G9H2, GSA_LACRJ  ;
DR   C1D9B6, GSA_LARHH  ;  Q1MPW7, GSA_LAWIP  ;  Q5X529, GSA_LEGPA  ;
DR   A5IC29, GSA_LEGPC  ;  Q5ZVA6, GSA_LEGPH  ;  Q5WWG1, GSA_LEGPL  ;
DR   Q6AHE8, GSA_LEIXX  ;  B0SF64, GSA_LEPBA  ;  Q04NV4, GSA_LEPBJ  ;
DR   Q04X52, GSA_LEPBL  ;  B0SNK3, GSA_LEPBP  ;  B1Y8G2, GSA_LEPCP  ;
DR   Q75G04, GSA_LEPIC  ;  Q8EY44, GSA_LEPIN  ;  A0L3S9, GSA_MAGSM  ;
DR   Q65U43, GSA_MANSM  ;  A1TYG5, GSA_MARAV  ;  A6VUX8, GSA_MARMS  ;
DR   A6UWB3, GSA_META3  ;  Q8TT57, GSA_METAC  ;  A7I7P2, GSA_METB6  ;
DR   Q46CH1, GSA_METBF  ;  Q12WM7, GSA_METBU  ;  Q60CV0, GSA_METCA  ;
DR   Q1GXW0, GSA_METFK  ;  Q2FTK5, GSA_METHJ  ;  B3DY05, GSA_METI4  ;
DR   Q58020, GSA_METJA  ;  Q8TYL6, GSA_METKA  ;  A2SQU3, GSA_METLZ  ;
DR   A4FZY1, GSA_METM5  ;  A9A875, GSA_METM6  ;  A6VIL1, GSA_METM7  ;
DR   Q8PW58, GSA_METMA  ;  A3CU65, GSA_METMJ  ;  Q6M0P5, GSA_METMP  ;
DR   B8GJJ2, GSA_METPE  ;  A2SKQ7, GSA_METPP  ;  A5UML0, GSA_METS3  ;
DR   A4YD91, GSA_METS5  ;  Q2NF42, GSA_METST  ;  O26330, GSA_METTH  ;
DR   A0B885, GSA_METTP  ;  A6URL2, GSA_METVS  ;  B0JPW6, GSA_MICAN  ;
DR   Q2RJ31, GSA_MOOTA  ;  A0QLG2, GSA_MYCA1  ;  B1MHH1, GSA_MYCA9  ;
DR   P63507, GSA_MYCBO  ;  A1KG00, GSA_MYCBP  ;  C1AKK4, GSA_MYCBT  ;
DR   A4T358, GSA_MYCGI  ;  B8ZT67, GSA_MYCLB  ;  P46716, GSA_MYCLE  ;
DR   B2HRL5, GSA_MYCMM  ;  Q73SQ3, GSA_MYCPA  ;  A0QR33, GSA_MYCS2  ;
DR   A3PUB7, GSA_MYCSJ  ;  A1UAR1, GSA_MYCSK  ;  Q1BE73, GSA_MYCSS  ;
DR   A5TZQ4, GSA_MYCTA  ;  P63506, GSA_MYCTU  ;  A0PLS0, GSA_MYCUA  ;
DR   A1T3F2, GSA_MYCVP  ;  Q1DFA7, GSA_MYXXD  ;  Q3IT20, GSA_NATPD  ;
DR   B2A1H4, GSA_NATTJ  ;  B9LA83, GSA_NAUPA  ;  Q5FAH9, GSA_NEIG1  ;
DR   B4RNX2, GSA_NEIG2  ;  A9M1G6, GSA_NEIM0  ;  Q9JW10, GSA_NEIMA  ;
DR   Q9JXW0, GSA_NEIMB  ;  A1KS34, GSA_NEIMF  ;  Q0AFV1, GSA_NITEC  ;
DR   Q82UQ8, GSA_NITEU  ;  A9A1A0, GSA_NITMS  ;  Q2Y5Q5, GSA_NITMU  ;
DR   Q3JDH7, GSA_NITOC  ;  A6Q2X6, GSA_NITSB  ;  Q5YP79, GSA_NOCFA  ;
DR   A1SE06, GSA_NOCSJ  ;  B2J7M9, GSA_NOSP7  ;  Q8YS26, GSA_NOSS1  ;
DR   B1ZVF7, GSA_OPITP  ;  Q6YZE2, GSA_ORYSJ  ;  Q6MAC7, GSA_PARUW  ;
DR   Q9CNG9, GSA_PASMU  ;  C6DC32, GSA_PECCP  ;  Q3A7W5, GSA_PELCD  ;
DR   Q3B1A1, GSA_PELLD  ;  B4SGW1, GSA_PELPB  ;  A1ASE9, GSA_PELPD  ;
DR   A5D3M2, GSA_PELTS  ;  C0QQ98, GSA_PERMH  ;  Q7N845, GSA_PHOLL  ;
DR   Q6LUS3, GSA_PHOPR  ;  Q6L2G9, GSA_PICTO  ;  A1VSM6, GSA_POLNA  ;
DR   B1XT79, GSA_POLNS  ;  Q12EF7, GSA_POLSJ  ;  A4SVE6, GSA_POLSQ  ;
DR   B4S3Q6, GSA_PROA2  ;  Q6AB08, GSA_PROAC  ;  Q06774, GSA_PROFF  ;
DR   A3PBK8, GSA_PROM0  ;  A2C0U2, GSA_PROM1  ;  A8G3J9, GSA_PROM2  ;
DR   A2C7I7, GSA_PROM3  ;  A9BEA5, GSA_PROM4  ;  A2BVE5, GSA_PROM5  ;
DR   Q31C50, GSA_PROM9  ;  Q7VDA1, GSA_PROMA  ;  B4EUE1, GSA_PROMH  ;
DR   Q7V677, GSA_PROMM  ;  Q7V2J3, GSA_PROMP  ;  A2BPW6, GSA_PROMS  ;
DR   Q46GT9, GSA_PROMT  ;  A4SGT2, GSA_PROVI  ;  Q48DP1, GSA_PSE14  ;
DR   Q15YL3, GSA_PSEA6  ;  A6V0D2, GSA_PSEA7  ;  B7V9D9, GSA_PSEA8  ;
DR   Q02SE5, GSA_PSEAB  ;  P48247, GSA_PSEAE  ;  Q1I4H5, GSA_PSEE4  ;
DR   Q4K5I6, GSA_PSEF5  ;  C3K2K3, GSA_PSEFS  ;  Q3IHS1, GSA_PSEHT  ;
DR   A4XYV6, GSA_PSEMY  ;  A5W9H0, GSA_PSEP1  ;  Q3K6C0, GSA_PSEPF  ;
DR   B0KJV9, GSA_PSEPG  ;  Q88DP0, GSA_PSEPK  ;  B1J1Y6, GSA_PSEPW  ;
DR   Q87VY5, GSA_PSESM  ;  Q4ZNA0, GSA_PSEU2  ;  A4VQY0, GSA_PSEU5  ;
DR   Q4FVC4, GSA_PSYA2  ;  Q1QEE8, GSA_PSYCK  ;  A1ST92, GSA_PSYIN  ;
DR   A5WC94, GSA_PSYWF  ;  Q8ZYW1, GSA_PYRAE  ;  A4WN33, GSA_PYRAR  ;
DR   A3MWW7, GSA_PYRCJ  ;  A1RQR5, GSA_PYRIL  ;  Q1LQM3, GSA_RALME  ;
DR   B2U6Q7, GSA_RALPJ  ;  Q8Y1M4, GSA_RALSO  ;  A9WPI0, GSA_RENSM  ;
DR   Q7UPM9, GSA_RHOBA  ;  C0ZUX9, GSA_RHOE4  ;  Q21YQ0, GSA_RHOFD  ;
DR   C1AZ30, GSA_RHOOB  ;  Q0SF42, GSA_RHOSR  ;  A7NKV1, GSA_ROSCS  ;
DR   A5UU40, GSA_ROSS1  ;  Q1AUK6, GSA_RUBXD  ;  A1AVQ1, GSA_RUTMC  ;
DR   Q21MJ0, GSA_SACD2  ;  A4FPX3, GSA_SACEN  ;  B5F8R5, GSA_SALA4  ;
DR   A8M6S5, GSA_SALAI  ;  A9MPK7, GSA_SALAR  ;  Q57T53, GSA_SALCH  ;
DR   B5FJ01, GSA_SALDC  ;  B5R3G6, GSA_SALEP  ;  B5RHE0, GSA_SALG2  ;
DR   B4TK30, GSA_SALHS  ;  B4SUY4, GSA_SALNS  ;  Q5PD43, GSA_SALPA  ;
DR   A9N0P9, GSA_SALPB  ;  C0Q5R5, GSA_SALPC  ;  B5BL82, GSA_SALPK  ;
DR   Q2S1S3, GSA_SALRD  ;  B4TXQ6, GSA_SALSV  ;  Q8Z9B4, GSA_SALTI  ;
DR   A4XC73, GSA_SALTO  ;  E1W874, GSA_SALTS  ;  P0CL07, GSA_SALTY  ;
DR   A8G9U7, GSA_SERP5  ;  A1S3U0, GSA_SHEAM  ;  B8EBU3, GSA_SHEB2  ;
DR   A3D1R5, GSA_SHEB5  ;  A6WKL6, GSA_SHEB8  ;  A9L5J5, GSA_SHEB9  ;
DR   Q12KC8, GSA_SHEDO  ;  Q07YU5, GSA_SHEFN  ;  B0TIQ0, GSA_SHEHH  ;
DR   A3QBN5, GSA_SHELP  ;  Q8EHC8, GSA_SHEON  ;  A8H164, GSA_SHEPA  ;
DR   A4Y4G4, GSA_SHEPC  ;  B8CJG4, GSA_SHEPW  ;  A0KZS6, GSA_SHESA  ;
DR   A8FS76, GSA_SHESH  ;  Q0HG53, GSA_SHESM  ;  Q0HSE6, GSA_SHESR  ;
DR   A1RMG7, GSA_SHESW  ;  B1KHF6, GSA_SHEWM  ;  B2U2Z9, GSA_SHIB3  ;
DR   Q325Y5, GSA_SHIBS  ;  Q32JV4, GSA_SHIDS  ;  Q0T852, GSA_SHIF8  ;
DR   Q821C1, GSA_SHIFL  ;  Q3Z5K3, GSA_SHISS  ;  Q2NVQ0, GSA_SODGM  ;
DR   Q40147, GSA_SOLLC  ;  Q01YQ2, GSA_SOLUE  ;  A9GDD3, GSA_SORC5  ;
DR   P45621, GSA_SOYBN  ;  Q82E21, GSA_STRAW  ;  Q9F2S0, GSA_STRCO  ;
DR   B1VTD1, GSA_STRGG  ;  B4SI23, GSA_STRM5  ;  B2FT35, GSA_STRMK  ;
DR   A3CL81, GSA_STRSV  ;  C1DUY4, GSA_SULAA  ;  Q4JAM7, GSA_SULAC  ;
DR   Q30RJ4, GSA_SULDN  ;  C3MZR9, GSA_SULIA  ;  C4KJ00, GSA_SULIK  ;
DR   C3MJ22, GSA_SULIL  ;  C3MYE0, GSA_SULIM  ;  C3NF69, GSA_SULIN  ;
DR   C3N842, GSA_SULIY  ;  A6Q9P9, GSA_SULNB  ;  Q980U5, GSA_SULSO  ;
DR   B2V5U0, GSA_SULSY  ;  Q976H2, GSA_SULTO  ;  Q67KM3, GSA_SYMTH  ;
DR   Q2LVW6, GSA_SYNAS  ;  Q31QJ2, GSA_SYNE7  ;  A0LIP3, GSA_SYNFM  ;
DR   Q2JS70, GSA_SYNJA  ;  Q2JMP7, GSA_SYNJB  ;  B1XIT5, GSA_SYNP2  ;
DR   P24630, GSA_SYNP6  ;  A5GMT2, GSA_SYNPW  ;  Q7U598, GSA_SYNPX  ;
DR   A5GUJ2, GSA_SYNR3  ;  Q0I8G1, GSA_SYNS3  ;  Q3AWP4, GSA_SYNS9  ;
DR   Q3ALU9, GSA_SYNSC  ;  Q0AZ36, GSA_SYNWW  ;  Q55665, GSA_SYNY3  ;
DR   C6AR33, GSA_TERTT  ;  B7IHH3, GSA_THEAB  ;  Q9HKM6, GSA_THEAC  ;
DR   Q8DLK8, GSA_THEEB  ;  Q47LB3, GSA_THEFY  ;  A6LKX4, GSA_THEM4  ;
DR   B1YBL3, GSA_THENV  ;  B9L0Q2, GSA_THERP  ;  Q72K83, GSA_THET2  ;
DR   Q5SJS4, GSA_THET8  ;  Q97B25, GSA_THEVO  ;  B5YHH6, GSA_THEYD  ;
DR   Q31FB1, GSA_THICR  ;  Q3SFU6, GSA_THIDA  ;  B8GLE4, GSA_THISH  ;
DR   P31593, GSA_TOBAC  ;  C4LAK4, GSA_TOLAT  ;  Q110Z9, GSA_TRIEI  ;
DR   Q83H98, GSA_TROW8  ;  Q83FJ5, GSA_TROWT  ;  Q0W5T3, GSA_UNCMA  ;
DR   A1WMA0, GSA_VEREI  ;  A5CXH8, GSA_VESOH  ;  A5F945, GSA_VIBC3  ;
DR   Q9KU97, GSA_VIBCH  ;  C3LSN1, GSA_VIBCM  ;  Q5E2W6, GSA_VIBF1  ;
DR   B5FAL8, GSA_VIBFM  ;  A7MUU9, GSA_VIBHB  ;  Q87LY3, GSA_VIBPA  ;
DR   B7VJJ5, GSA_VIBSL  ;  Q8DBX8, GSA_VIBVU  ;  Q7MHY9, GSA_VIBVY  ;
DR   Q8D3C8, GSA_WIGBR  ;  Q7M847, GSA_WOLSU  ;  Q8PH40, GSA_XANAC  ;
DR   Q3BPP7, GSA_XANC5  ;  Q4UYA7, GSA_XANC8  ;  B0RP74, GSA_XANCB  ;
DR   Q06741, GSA_XANCH  ;  Q8P5R4, GSA_XANCP  ;  Q2P6E4, GSA_XANOM  ;
DR   B2SKS0, GSA_XANOP  ;  Q5H3I5, GSA_XANOR  ;  B2I6C2, GSA_XYLF2  ;
DR   Q9PB43, GSA_XYLFA  ;  B0U328, GSA_XYLFM  ;  Q87BW3, GSA_XYLFT  ;
DR   A1JJQ1, GSA_YERE8  ;  A7FM09, GSA_YERP3  ;  Q1C3X1, GSA_YERPA  ;
DR   B2K547, GSA_YERPB  ;  Q8ZBL9, GSA_YERPE  ;  A9R1E6, GSA_YERPG  ;
DR   Q1CLU7, GSA_YERPN  ;  A4TPW6, GSA_YERPP  ;  Q66EF1, GSA_YERPS  ;
DR   B1JK22, GSA_YERPY  ;
//
ID   5.4.4.1
DE   (Hydroxyamino)benzene mutase.
AN   HAB mutase.
AN   Hydroxylaminobenzene hydroxymutase.
AN   Hydroxylaminobenzene mutase.
CA   (Hydroxyamino)benzene = 2-aminophenol.
//
ID   5.4.4.2
DE   Isochorismate synthase.
AN   Isochorismate mutase.
AN   Isochorismate synthetase.
CA   Chorismate = isochorismate.
CF   Magnesium.
CC   -!- The reaction is reversible.
CC   -!- Formerly EC 5.4.99.6.
DR   P23300, AMOA_AERHY ;  P45744, DHBC_BACSU ;  P0AEJ3, ENTC_ECO57 ;
DR   P0AEJ2, ENTC_ECOLI ;  Q9S7H8, ICS1_ARATH ;  Q9M9V6, ICS2_ARATH ;
DR   Q9ZPC0, ICS_CATRO  ;  Q7TYQ1, MBTI_MYCBO ;  Q73XV3, MBTI_MYCPA ;
DR   Q7D785, MBTI_MYCTU ;  P23973, MENF_BACSU ;  P38051, MENF_ECOLI ;
DR   P44613, MENF_HAEIN ;  O05851, MENF_MYCTU ;  Q9CPI5, MENF_PASMU ;
DR   Q51508, PCHA_PSEAE ;  O07898, VIBC_VIBCH ;
//
ID   5.4.4.3
DE   3-(hydroxyamino)phenol mutase.
AN   3-hydroxylaminophenol mutase.
AN   3HAP mutase.
CA   3-hydroxyaminophenol = aminohydroquinone.
//
ID   5.4.99.1
DE   Methylaspartate mutase.
AN   Beta-methylaspartate-glutamate mutase.
AN   Glutamate isomerase.
AN   Glutamate mutase.
AN   Glutamic isomerase.
AN   Glutamic mutase.
AN   Methylaspartic acid mutase.
CA   L-threo-3-methylaspartate = L-glutamate.
CF   Cobalamin.
DR   P80077, GLME_CLOCO ;  Q05509, GLME_CLOTT ;  Q5V467, MAMA1_HALMA;
DR   Q5V3F0, MAMA2_HALMA;  Q3AFA7, MAMA_CARHZ ;  P80078, MAMA_CLOCO ;
DR   Q890S0, MAMA_CLOTE ;  Q05488, MAMA_CLOTT ;  Q24SG7, MAMA_DESHY ;
DR   P58620, MAMA_ECO57 ;  Q8RHY7, MAMA_FUSNN ;  Q9HN21, MAMA_HALSA ;
DR   Q32IJ3, MAMA_SHIDS ;  P61191, MAMA_TREDE ;  A1JSN5, MAMA_YERE8 ;
//
ID   5.4.99.2
DE   Methylmalonyl-CoA mutase.
AN   (R)-2-methyl-3-oxopropanoyl-CoA CoA-carbonylmutase.
AN   (S)-methylmalonyl-CoA mutase.
AN   Methylmalonyl coenzyme A carbonylmutase.
AN   Methylmalonyl coenzyme A mutase.
AN   Methylmalonyl-CoA CoA-carbonyl mutase.
CA   (R)-methylmalonyl-CoA = succinyl-CoA.
CF   Cobalamin.
PR   PROSITE; PDOC00470;
DR   Q9GK13, MUTA_BOVIN ;  Q23381, MUTA_CAEEL ;  P22033, MUTA_HUMAN ;
DR   Q8HXX1, MUTA_MACFA ;  P16332, MUTA_MOUSE ;  P65486, MUTA_MYCBO ;
DR   P65485, MUTA_MYCTU ;  Q8MI68, MUTA_PIG   ;  Q5RFN2, MUTA_PONAB ;
DR   Q59676, MUTA_PORGI ;  P11652, MUTA_PROFR ;  Q05064, MUTA_STRCM ;
DR   P65488, MUTB_MYCBO ;  P65487, MUTB_MYCTU ;  Q59677, MUTB_PORGI ;
DR   P11653, MUTB_PROFR ;  O86028, MUTB_RHIME ;  Q05065, MUTB_STRCM ;
//
ID   5.4.99.3
DE   2-acetolactate mutase.
AN   Acetohydroxy acid isomerase.
CA   2-acetolactate = 3-hydroxy-3-methyl-2-oxobutanoate.
CF   L-ascorbate.
CC   -!- Also converts 2-aceto-2-hydroxybutanoate to 3-hydroxy-3-methyl-2-
CC       oxopentanoate.
//
ID   5.4.99.4
DE   2-methyleneglutarate mutase.
AN   Alpha-methyleneglutarate mutase.
CA   2-methyleneglutarate = 2-methylene-3-methylsuccinate.
CF   Cobalamin.
CC   -!- Forms part of the nicotinate-fermentation catabolism pathway in
CC       Eubacterium barkeri.
CC   -!- Other enzymes involved in this pathway are EC 1.17.1.5, EC 1.3.7.1,
CC       EC 3.5.2.18, EC 1.1.1.291, EC 5.3.3.6, EC 4.2.1.85 and EC 4.1.3.32.
DR   Q59268, MGM_EUBBA  ;
//
ID   5.4.99.5
DE   Chorismate mutase.
AN   Hydroxyphenylpyruvate synthase.
CA   Chorismate = prephenate.
PR   PROSITE; PDOC51167;
DR   P39912, AROG_BACSU ;  P42738, CHMU_ARATH ;  P19080, CHMU_BACSU ;
DR   P42517, CHMU_ENTAG ;  O13739, CHMU_SCHPO ;  P32178, CHMU_YEAST ;
DR   O67085, PHEA_AQUAE ;  P57472, PHEA_BUCAI ;  Q8K9F8, PHEA_BUCAP ;
DR   Q89AE5, PHEA_BUCBP ;  P0A9J9, PHEA_ECO57 ;  P0A9J8, PHEA_ECOLI ;
DR   Q02286, PHEA_ENTAG ;  P43900, PHEA_HAEIN ;  Q9ZHY3, PHEA_NEIG1 ;
DR   Q9HZ67, PHEA_PSEAE ;  P27603, PHEA_PSEST ;  P0A9K0, PHEA_SHIFL ;
DR   P07023, TYRA_ECOLI ;  Q02287, TYRA_ENTAG ;  P43902, TYRA_HAEIN ;
DR   Q8EH68, TYRA_SHEON ;
//
ID   5.4.99.6
DE   Transferred entry: 5.4.4.2.
//
ID   5.4.99.7
DE   Lanosterol synthase.
AN   2,3-epoxysqualene--lanosterol cyclase.
AN   Oxidosqualene--lanosterol cyclase.
AN   Squalene-2,3-oxide-lanosterol cyclase.
CA   (S)-2,3-epoxysqualene = lanosterol.
CC   -!- Formerly EC 1.14.1.3 and EC 1.99.1.13.
PR   PROSITE; PDOC00825;
DR   P84466, ERG7_BOVIN ;  Q04782, ERG7_CANAL ;  P48449, ERG7_HUMAN ;
DR   Q8BLN5, ERG7_MOUSE ;  Q96WJ0, ERG7_PNECA ;  P48450, ERG7_RAT   ;
DR   Q10231, ERG7_SCHPO ;  P38604, ERG7_YEAST ;  Q1G1A4, LAS1_ARATH ;
//
ID   5.4.99.8
DE   Cycloartenol synthase.
AN   2,3-epoxysqualene--cycloartenol cyclase.
CA   (S)-2,3-epoxysqualene = cycloartenol.
PR   PROSITE; PDOC00825;
DR   P38605, CAS1_ARATH ;  Q55D85, CAS1_DICDI ;
//
ID   5.4.99.9
DE   UDP-galactopyranose mutase.
CA   UDP-D-galactopyranose = UDP-D-galacto-1,4-furanose.
DR   Q48485, GLF1_KLEPN ;  Q48481, GLF8_KLEPN ;  P37747, GLF_ECOLI  ;
DR   Q49398, GLF_MYCGE  ;  P75499, GLF_MYCPN  ;
//
ID   5.4.99.10
DE   Transferred entry: 5.4.99.11.
//
ID   5.4.99.11
DE   Isomaltulose synthase.
AN   Isomaltulose synthetase.
AN   Sucrose glucosylmutase.
CA   Sucrose = 6-O-alpha-D-glucopyranosyl-D-fructofuranose.
CC   -!- Simultaneously produces isomaltulose (6-O-alpha-D-glucopyranosyl-D-
CC       fructose) and smaller amounts of trehalulose (1-O-alpha-D-
CC       glucopyranosyl-beta-D-fructose) from sucrose.
CC   -!- Formerly EC 5.4.99.10.
//
ID   5.4.99.12
DE   tRNA pseudouridine(38-40) synthase.
AN   PSUI.
AN   tRNA pseudouridylate synthase I.
CA   tRNA uridine(38-40) = tRNA pseudouridine(38-40).
CC   -!- The uridylate residues at positions 38, 39 and 40 of nearly all tRNAs
CC       are isomerized to pseudouridine.
CC   -!- TruA specifically modifies uridines at positions 38, 39, and/or 40 in
CC       the anticodon stem loop of tRNAs with highly divergent sequences and
CC       structures.
DR   Q6I4Q2, TRUA1_BACAN;  Q73F64, TRUA1_BACC1;  Q814C2, TRUA1_BACCR;
DR   Q63H59, TRUA1_BACCZ;  Q6HPM7, TRUA1_BACHK;  Q8XLQ0, TRUA1_CLOPE;
DR   Q893H3, TRUA1_CLOTE;  Q6ANM1, TRUA1_DESPS;  Q6MEE7, TRUA1_PARUW;
DR   Q6I3T8, TRUA2_BACAN;  Q73E17, TRUA2_BACC1;  Q813Z9, TRUA2_BACCR;
DR   Q63GF1, TRUA2_BACCZ;  Q6HNW5, TRUA2_BACHK;  Q8XHV5, TRUA2_CLOPE;
DR   Q890R5, TRUA2_CLOTE;  Q6AKP0, TRUA2_DESPS;  Q6MDE3, TRUA2_PARUW;
DR   A1TLH0, TRUA_ACIAC ;  Q6FEV2, TRUA_ACIAD ;  B7H0S9, TRUA_ACIB3 ;
DR   B7I4E8, TRUA_ACIB5 ;  B2I367, TRUA_ACIBC ;  B0VLA5, TRUA_ACIBS ;
DR   A3M1T4, TRUA_ACIBT ;  B0V4L0, TRUA_ACIBY ;  A5FVK4, TRUA_ACICJ ;
DR   B9MDL6, TRUA_ACIET ;  A1WAT5, TRUA_ACISJ ;  A3N0R2, TRUA_ACTP2 ;
DR   B3GXP8, TRUA_ACTP7 ;  B0BPI7, TRUA_ACTPJ ;  A6VQ16, TRUA_ACTSZ ;
DR   A0KLN7, TRUA_AERHH ;  A4SNT8, TRUA_AERS4 ;  Q8UIC9, TRUA_AGRT5 ;
DR   B9JQX0, TRUA_AGRVS ;  B2UNB6, TRUA_AKKM8 ;  Q0VPI7, TRUA_ALCBS ;
DR   B6EIW6, TRUA_ALISL ;  B9KIN8, TRUA_ANAMF ;  Q5PAN6, TRUA_ANAMM ;
DR   Q2GKK4, TRUA_ANAPZ ;  B9MKC1, TRUA_ANATD ;  B7GJ99, TRUA_ANOFW ;
DR   O66953, TRUA_AQUAE ;  O28544, TRUA_ARCFU ;  Q5P1J2, TRUA_AROAE ;
DR   Q2NIY3, TRUA_AYWBP ;  A8IQL3, TRUA_AZOC5 ;  B6YQE4, TRUA_AZOPC ;
DR   A7Z0S0, TRUA_BACA2 ;  Q5LGZ6, TRUA_BACFN ;  Q64XV0, TRUA_BACFR ;
DR   Q9Z9J0, TRUA_BACHD ;  Q65P74, TRUA_BACLD ;  A8F9B7, TRUA_BACP2 ;
DR   Q5WLN0, TRUA_BACSK ;  P70973, TRUA_BACSU ;  Q45557, TRUA_BACSV ;
DR   Q89ZY4, TRUA_BACTN ;  A1UUB6, TRUA_BARBK ;  Q6G547, TRUA_BARHE ;
DR   Q6G1G9, TRUA_BARQU ;  A9ILJ7, TRUA_BART1 ;  Q6MQH6, TRUA_BDEBA ;
DR   B2IEW0, TRUA_BEII9 ;  B8DW40, TRUA_BIFA0 ;  B3DQE2, TRUA_BIFLD ;
DR   Q8CY46, TRUA_BIFLO ;  Q7U356, TRUA_BLOFL ;  Q492H3, TRUA_BLOPB ;
DR   Q2KYM0, TRUA_BORA1 ;  Q0SPF2, TRUA_BORAP ;  Q7U386, TRUA_BORBR ;
DR   P70830, TRUA_BORBU ;  B7J0V1, TRUA_BORBZ ;  B5RLM0, TRUA_BORDL ;
DR   Q663A0, TRUA_BORGA ;  B2S1K1, TRUA_BORHD ;  Q7U376, TRUA_BORPA ;
DR   A9IRL0, TRUA_BORPD ;  Q7U363, TRUA_BORPE ;  B5RQJ5, TRUA_BORRA ;
DR   A1QYG5, TRUA_BORT9 ;  C0QZT8, TRUA_BRAHW ;  Q89BP1, TRUA_BRAJA ;
DR   A5ESQ5, TRUA_BRASB ;  A4YLC1, TRUA_BRASO ;  C0ZIL2, TRUA_BREBN ;
DR   Q2YJQ4, TRUA_BRUA2 ;  Q576T1, TRUA_BRUAB ;  A9MCV8, TRUA_BRUC2 ;
DR   C0RMH2, TRUA_BRUMB ;  Q8YDB2, TRUA_BRUME ;  A5VVT9, TRUA_BRUO2 ;
DR   A9WW43, TRUA_BRUSI ;  Q60CV4, TRUA_BRUSU ;  B8D8Z8, TRUA_BUCA5 ;
DR   P57295, TRUA_BUCAI ;  Q8K9U4, TRUA_BUCAP ;  B8D7A3, TRUA_BUCAT ;
DR   P59508, TRUA_BUCBP ;  B1Z1N7, TRUA_BURA4 ;  Q1BM62, TRUA_BURCA ;
DR   B1K370, TRUA_BURCC ;  A0AZ67, TRUA_BURCH ;  Q0BAC2, TRUA_BURCM ;
DR   Q83WJ5, TRUA_BURM1 ;  A3MBU2, TRUA_BURM7 ;  A2S134, TRUA_BURM9 ;
DR   Q62AJ2, TRUA_BURMA ;  A1UZ38, TRUA_BURMS ;  A3P7N2, TRUA_BURP0 ;
DR   Q3JKH3, TRUA_BURP1 ;  A3NM70, TRUA_BURP6 ;  B2JQE6, TRUA_BURP8 ;
DR   B2T9N4, TRUA_BURPP ;  Q63JL6, TRUA_BURPS ;  Q393X8, TRUA_BURS3 ;
DR   Q2T7H3, TRUA_BURTA ;  A4JMC2, TRUA_BURVG ;  Q13S27, TRUA_BURXL ;
DR   A4XKB7, TRUA_CALS8 ;  A0RNY9, TRUA_CAMFF ;  A8FLN6, TRUA_CAMJ8 ;
DR   A7H426, TRUA_CAMJD ;  Q9PP96, TRUA_CAMJE ;  A1VZH1, TRUA_CAMJJ ;
DR   Q5HUW9, TRUA_CAMJR ;  B8GYF0, TRUA_CAUCN ;  Q9ABF0, TRUA_CAUCR ;
DR   B0T1S6, TRUA_CAUSK ;  A9WH95, TRUA_CHLAA ;  Q5L6V3, TRUA_CHLAB ;
DR   B8G6P6, TRUA_CHLAD ;  Q3AQT7, TRUA_CHLCH ;  Q253C0, TRUA_CHLFF ;
DR   B3EIU9, TRUA_CHLL2 ;  Q9PJT0, TRUA_CHLMU ;  A1BFF0, TRUA_CHLPD ;
DR   Q9Z7X4, TRUA_CHLPN ;  B9LJG1, TRUA_CHLSY ;  B0B836, TRUA_CHLT2 ;
DR   Q3KLN5, TRUA_CHLTA ;  B0BCA1, TRUA_CHLTB ;  Q8KDR7, TRUA_CHLTE ;
DR   O84469, TRUA_CHLTR ;  Q7NUD6, TRUA_CHRVO ;  A8ADR1, TRUA_CITK8 ;
DR   Q97EL1, TRUA_CLOAB ;  A6LPU5, TRUA_CLOB8 ;  B2UYE4, TRUA_CLOBA ;
DR   B2TIK9, TRUA_CLOBB ;  B8I814, TRUA_CLOCE ;  A5N4T0, TRUA_CLOK5 ;
DR   A3DJK8, TRUA_CLOTH ;  Q47XK4, TRUA_COLP3 ;  B5Y955, TRUA_COPPD ;
DR   P60349, TRUA_CORDI ;  Q8FS31, TRUA_COREF ;  Q8NSV0, TRUA_CORGL ;
DR   B6J6W3, TRUA_COXB1 ;  B6J0H0, TRUA_COXB2 ;  A9KFZ5, TRUA_COXBN ;
DR   A9ND24, TRUA_COXBR ;  Q0K8H3, TRUA_CUPNH ;  Q46YW3, TRUA_CUPPJ ;
DR   B3R117, TRUA_CUPTR ;  B7K222, TRUA_CYAP8 ;  Q47HQ7, TRUA_DECAR ;
DR   Q9RS37, TRUA_DEIRA ;  A9BNH5, TRUA_DELAS ;  C6BW69, TRUA_DESAD ;
DR   B1I1B5, TRUA_DESAP ;  Q30XU3, TRUA_DESDG ;  C4XPZ9, TRUA_DESMR ;
DR   A4J151, TRUA_DESRM ;  Q72DL8, TRUA_DESVH ;  B8DRQ6, TRUA_DESVM ;
DR   A1VF73, TRUA_DESVV ;  B5YDX5, TRUA_DICT6 ;  B8E1G5, TRUA_DICTD ;
DR   A8LNZ7, TRUA_DINSH ;  A7ZPD3, TRUA_ECO24 ;  B7UFX6, TRUA_ECO27 ;
DR   B7MG82, TRUA_ECO45 ;  B7LBH2, TRUA_ECO55 ;  P65845, TRUA_ECO57 ;
DR   B5YXV8, TRUA_ECO5E ;  B7NNZ9, TRUA_ECO7I ;  B7MXZ5, TRUA_ECO81 ;
DR   B7M6J9, TRUA_ECO8A ;  C4ZVL1, TRUA_ECOBW ;  B1X929, TRUA_ECODH ;
DR   A8A2I7, TRUA_ECOHS ;  A1ADG7, TRUA_ECOK1 ;  Q0TFC8, TRUA_ECOL5 ;
DR   P65844, TRUA_ECOL6 ;  B1IXM4, TRUA_ECOLC ;  P07649, TRUA_ECOLI ;
DR   B7N5T0, TRUA_ECOLU ;  B6I4U6, TRUA_ECOSE ;  B1LLS3, TRUA_ECOSM ;
DR   Q1R994, TRUA_ECOUT ;  Q3YS43, TRUA_EHRCJ ;  Q2GGK1, TRUA_EHRCR ;
DR   Q5FGS1, TRUA_EHRRG ;  Q5HBA4, TRUA_EHRRW ;  A4WCV2, TRUA_ENT38 ;
DR   A7MH65, TRUA_ENTS8 ;  Q6D2N7, TRUA_ERWCT ;  Q2NCT7, TRUA_ERYLH ;
DR   B7LLF2, TRUA_ESCF3 ;  B1YH83, TRUA_EXIS2 ;  C4KZL4, TRUA_EXISA ;
DR   A7HKV8, TRUA_FERNB ;  B0S2E1, TRUA_FINM2 ;  B0U0B1, TRUA_FRAP2 ;
DR   Q2JFE6, TRUA_FRASC ;  Q14HI8, TRUA_FRAT1 ;  A7NCA0, TRUA_FRATF ;
DR   Q2A3D7, TRUA_FRATH ;  B2SGK2, TRUA_FRATM ;  A0Q6C2, TRUA_FRATN ;
DR   Q0BLV1, TRUA_FRATO ;  Q5NG36, TRUA_FRATT ;  A4IXW8, TRUA_FRATW ;
DR   Q8R601, TRUA_FUSNN ;  B5EFM8, TRUA_GEOBB ;  Q5L3Q7, TRUA_GEOKA ;
DR   B9M6W5, TRUA_GEOSF ;  P60350, TRUA_GEOSL ;  C6E4S9, TRUA_GEOSM ;
DR   C5D3U9, TRUA_GEOSW ;  A4IJL9, TRUA_GEOTN ;  A5GB00, TRUA_GEOUR ;
DR   Q7MBB9, TRUA_GLOVI ;  Q5FPX3, TRUA_GLUOX ;  Q7U335, TRUA_HAEDU ;
DR   Q4QL79, TRUA_HAEI8 ;  A5UIY2, TRUA_HAEIG ;  P45291, TRUA_HAEIN ;
DR   B8F382, TRUA_HAEPS ;  Q0I4X5, TRUA_HAES1 ;  B0USP1, TRUA_HAES2 ;
DR   Q5UXW0, TRUA_HALMA ;  B0R6V1, TRUA_HALS3 ;  Q9HNP6, TRUA_HALSA ;
DR   Q17YM7, TRUA_HELAH ;  Q7U328, TRUA_HELHP ;  B6JMT3, TRUA_HELP2 ;
DR   B5Z889, TRUA_HELPG ;  Q1CSH3, TRUA_HELPH ;  Q9ZKC0, TRUA_HELPJ ;
DR   B2UUJ8, TRUA_HELPS ;  P56144, TRUA_HELPY ;  A4G4G0, TRUA_HERAR ;
DR   Q9Y606, TRUA_HUMAN ;  B4U9D9, TRUA_HYDS0 ;  Q0C4U8, TRUA_HYPNA ;
DR   Q5QUE5, TRUA_IDILO ;  A6T009, TRUA_JANMA ;  Q28LN3, TRUA_JANSC ;
DR   B5XNR9, TRUA_KLEP3 ;  A6TC04, TRUA_KLEP7 ;  C5CGS8, TRUA_KOSOT ;
DR   Q5FM60, TRUA_LACAC ;  Q03PY8, TRUA_LACBA ;  Q035B5, TRUA_LACC3 ;
DR   B3WAI6, TRUA_LACCB ;  Q04BY4, TRUA_LACDB ;  B2GDT8, TRUA_LACF3 ;
DR   A8YTB0, TRUA_LACH4 ;  Q74L59, TRUA_LACJO ;  Q9CI80, TRUA_LACLA ;
DR   A2RIH1, TRUA_LACLM ;  Q031N1, TRUA_LACLS ;  Q88XU9, TRUA_LACPL ;
DR   A5VLH4, TRUA_LACRD ;  B2G8U7, TRUA_LACRJ ;  Q1WSC1, TRUA_LACS1 ;
DR   Q38UV3, TRUA_LACSS ;  Q1MPG1, TRUA_LAWIP ;  Q5X5Q4, TRUA_LEGPA ;
DR   A5IBF5, TRUA_LEGPC ;  Q5ZVY6, TRUA_LEGPH ;  Q5WX34, TRUA_LEGPL ;
DR   Q6AD25, TRUA_LEIXX ;  B0SC03, TRUA_LEPBA ;  B0SJC4, TRUA_LEPBP ;
DR   Q8CXS6, TRUA_LEPIN ;  B1MVY3, TRUA_LEUCK ;  Q03ZL3, TRUA_LEUMM ;
DR   Q927P1, TRUA_LISIN ;  C1KZ13, TRUA_LISMC ;  Q71WI0, TRUA_LISMF ;
DR   B8DB42, TRUA_LISMH ;  Q8Y457, TRUA_LISMO ;  A0ALT4, TRUA_LISW6 ;
DR   B1HMV0, TRUA_LYSSC ;  Q2WAT0, TRUA_MAGSA ;  Q65TC8, TRUA_MANSM ;
DR   Q0ASJ7, TRUA_MARMM ;  Q6F1W2, TRUA_MESFL ;  Q11LD0, TRUA_MESSB ;
DR   Q8TU65, TRUA_METAC ;  Q46CU8, TRUA_METBF ;  Q12VJ7, TRUA_METBU ;
DR   B7KVW3, TRUA_METC4 ;  Q604P1, TRUA_METCA ;  A9W377, TRUA_METEP ;
DR   Q1H0L9, TRUA_METFK ;  B3E0A0, TRUA_METI4 ;  Q59069, TRUA_METJA ;
DR   Q8TWZ3, TRUA_METKA ;  A2SU30, TRUA_METLZ ;  A9A828, TRUA_METM6 ;
DR   Q8PWT1, TRUA_METMA ;  A3CXX4, TRUA_METMJ ;  Q6M0K2, TRUA_METMP ;
DR   B8IFQ2, TRUA_METNO ;  B1ZGA6, TRUA_METPB ;  B8GFU5, TRUA_METPE ;
DR   A2SHS6, TRUA_METPP ;  B1M6N9, TRUA_METRJ ;  A5ULI2, TRUA_METS3 ;
DR   B0UP40, TRUA_METS4 ;  B8ENG8, TRUA_METSB ;  Q2NHB4, TRUA_METST ;
DR   O26928, TRUA_METTH ;  A0B7V0, TRUA_METTP ;  Q2RFT1, TRUA_MOOTA ;
DR   Q9WU56, TRUA_MOUSE ;  P65847, TRUA_MYCBO ;  Q2SRI4, TRUA_MYCCT ;
DR   Q7NAQ9, TRUA_MYCGA ;  P47428, TRUA_MYCGE ;  Q9X796, TRUA_MYCLE ;
DR   Q6MSQ4, TRUA_MYCMS ;  Q73S41, TRUA_MYCPA ;  Q8CXQ1, TRUA_MYCPE ;
DR   Q50291, TRUA_MYCPN ;  P65846, TRUA_MYCTU ;  Q93NE2, TRUA_MYXXA ;
DR   P60354, TRUA_NANEQ ;  Q3IMP6, TRUA_NATPD ;  B2A4Q5, TRUA_NATTJ ;
DR   Q5F5V8, TRUA_NEIG1 ;  B4RR02, TRUA_NEIG2 ;  A9M0B8, TRUA_NEIM0 ;
DR   Q9JWF1, TRUA_NEIMA ;  Q9JXI2, TRUA_NEIMB ;  A1KWB6, TRUA_NEIMF ;
DR   Q2GF33, TRUA_NEOSM ;  Q0AGX7, TRUA_NITEC ;  Q820P8, TRUA_NITEU ;
DR   Q1QH76, TRUA_NITHX ;  Q3JCC0, TRUA_NITOC ;  Q3SN27, TRUA_NITWN ;
DR   Q5Z1K7, TRUA_NOCFA ;  Q8YPK5, TRUA_NOSS1 ;  Q8CXP1, TRUA_OCEIH ;
DR   A6WYK9, TRUA_OCHA4 ;  Q04G54, TRUA_OENOB ;  B6JJP6, TRUA_OLICO ;
DR   P60351, TRUA_ONYPE ;  A5CET3, TRUA_ORITB ;  B3CSN9, TRUA_ORITI ;
DR   A6LDA7, TRUA_PARD8 ;  A1AZF2, TRUA_PARDP ;  A7HPQ3, TRUA_PARL1 ;
DR   P57861, TRUA_PASMU ;  Q3A3B5, TRUA_PELCD ;  Q3B3P4, TRUA_PELLD ;
DR   B4SA76, TRUA_PELPB ;  A1AUF4, TRUA_PELPD ;  Q4FNF9, TRUA_PELUB ;
DR   A9BGW7, TRUA_PETMO ;  Q7MB17, TRUA_PHOLL ;  Q6LNU5, TRUA_PHOPR ;
DR   B3R022, TRUA_PHYMT ;  Q6L0Y7, TRUA_PICTO ;  A1VRR5, TRUA_POLNA ;
DR   B1XV49, TRUA_POLNS ;  Q126M3, TRUA_POLSJ ;  A4SWX4, TRUA_POLSQ ;
DR   B2RIV6, TRUA_PORG3 ;  Q6A6S8, TRUA_PROAC ;  A3PF23, TRUA_PROM0 ;
DR   A8G737, TRUA_PROM2 ;  A2CC53, TRUA_PROM3 ;  A9BCM2, TRUA_PROM4 ;
DR   A2BYR1, TRUA_PROM5 ;  Q318K9, TRUA_PROM9 ;  Q7V9Y7, TRUA_PROMA ;
DR   Q7TUP1, TRUA_PROMM ;  Q7TU31, TRUA_PROMP ;  A2BTB3, TRUA_PROMS ;
DR   A4SE87, TRUA_PROVI ;  Q15VG2, TRUA_PSEA6 ;  O87016, TRUA_PSEAE ;
DR   Q3IF40, TRUA_PSEHT ;  A1SW72, TRUA_PSYIN ;  Q9UZZ3, TRUA_PYRAB ;
DR   Q8ZXR6, TRUA_PYRAE ;  A4WHI1, TRUA_PYRAR ;  A3MU09, TRUA_PYRCJ ;
DR   Q8U2C1, TRUA_PYRFU ;  O58941, TRUA_PYRHO ;  A1RU12, TRUA_PYRIL ;
DR   Q5JI92, TRUA_PYRKO ;  B2U6Z1, TRUA_RALPJ ;  Q8XXX8, TRUA_RALSO ;
DR   Q4KM92, TRUA_RAT   ;  Q98D55, TRUA_RHILO ;  B5ZN21, TRUA_RHILW ;
DR   Q92SH4, TRUA_RHIME ;  C3MF26, TRUA_RHISN ;  Q7TU07, TRUA_RHOBA ;
DR   B6IPI0, TRUA_RHOCS ;  Q21XI4, TRUA_RHOFD ;  Q2J2C4, TRUA_RHOP2 ;
DR   Q07TX2, TRUA_RHOP5 ;  P60352, TRUA_RHOPA ;  Q21B58, TRUA_RHOPB ;
DR   Q13F20, TRUA_RHOPS ;  Q2RNZ9, TRUA_RHORT ;  A3PLW1, TRUA_RHOS1 ;
DR   Q3J0D9, TRUA_RHOS4 ;  A4WPU4, TRUA_RHOS5 ;  B9KKX4, TRUA_RHOSK ;
DR   C3PLZ3, TRUA_RICAE ;  A8GQ80, TRUA_RICAH ;  A8GUM4, TRUA_RICB8 ;
DR   Q1RKH3, TRUA_RICBR ;  A8F079, TRUA_RICCK ;  Q92FZ9, TRUA_RICCN ;
DR   Q4UJT2, TRUA_RICFE ;  Q9ZCA3, TRUA_RICPR ;  C4K2W2, TRUA_RICPU ;
DR   B0BVL0, TRUA_RICRO ;  A8GU17, TRUA_RICRS ;  Q68VQ6, TRUA_RICTY ;
DR   A7NR34, TRUA_ROSCS ;  Q168C1, TRUA_ROSDO ;  A5USG0, TRUA_ROSS1 ;
DR   B5EZQ2, TRUA_SALA4 ;  A9MJ57, TRUA_SALAR ;  Q57LY6, TRUA_SALCH ;
DR   B5FPL2, TRUA_SALDC ;  B5R349, TRUA_SALEP ;  B5RCJ3, TRUA_SALG2 ;
DR   B4TBN7, TRUA_SALHS ;  B4SZP0, TRUA_SALNS ;  Q5PCV6, TRUA_SALPA ;
DR   A9N476, TRUA_SALPB ;  C0PZZ5, TRUA_SALPC ;  B5BCH8, TRUA_SALPK ;
DR   Q2S4S9, TRUA_SALRD ;  B4TQA4, TRUA_SALSV ;  Q8Z500, TRUA_SALTI ;
DR   Q8ZNB9, TRUA_SALTY ;  A1S7J9, TRUA_SHEAM ;  B8EEB7, TRUA_SHEB2 ;
DR   A3D666, TRUA_SHEB5 ;  A6WQ04, TRUA_SHEB8 ;  A9KTU7, TRUA_SHEB9 ;
DR   Q12P55, TRUA_SHEDO ;  Q084R8, TRUA_SHEFN ;  B0TKZ4, TRUA_SHEHH ;
DR   A3QFC4, TRUA_SHELP ;  A8H305, TRUA_SHEPA ;  A4Y879, TRUA_SHEPC ;
DR   B8CPW5, TRUA_SHEPW ;  A0KV94, TRUA_SHESA ;  A8FTU0, TRUA_SHESH ;
DR   Q0HKB3, TRUA_SHESM ;  Q0HWL5, TRUA_SHESR ;  A1RIB0, TRUA_SHESW ;
DR   B1KKN8, TRUA_SHEWM ;  B2TWA0, TRUA_SHIB3 ;  Q31YE0, TRUA_SHIBS ;
DR   Q32DL8, TRUA_SHIDS ;  Q0T2G7, TRUA_SHIF8 ;  Q83QR3, TRUA_SHIFL ;
DR   Q3YZP3, TRUA_SHISS ;  Q5LNR0, TRUA_SILPO ;  Q1GE00, TRUA_SILST ;
DR   A6U5I6, TRUA_SINMW ;  Q01WL4, TRUA_SOLUE ;  Q1GWK1, TRUA_SPHAL ;
DR   A5VDL9, TRUA_SPHWW ;  P60353, TRUA_SPIKU ;  A7X5B5, TRUA_STAA1 ;
DR   A6U3U4, TRUA_STAA2 ;  Q2FES0, TRUA_STAA3 ;  Q2FW37, TRUA_STAA8 ;
DR   A5IV03, TRUA_STAA9 ;  Q2YYM7, TRUA_STAAB ;  Q5HDY9, TRUA_STAAC ;
DR   A6QJ61, TRUA_STAAE ;  P65848, TRUA_STAAM ;  P65849, TRUA_STAAN ;
DR   Q6GEL6, TRUA_STAAR ;  Q6G7A2, TRUA_STAAS ;  A8Z326, TRUA_STAAT ;
DR   Q8NVB7, TRUA_STAAW ;  B9DM46, TRUA_STACT ;  Q5HM30, TRUA_STAEQ ;
DR   Q8CML6, TRUA_STAES ;  Q4L882, TRUA_STAHJ ;  Q49ZD7, TRUA_STAS1 ;
DR   Q3K3S9, TRUA_STRA1 ;  Q8E7Q5, TRUA_STRA3 ;  Q8CX20, TRUA_STRA5 ;
DR   Q82DM1, TRUA_STRAW ;  O86776, TRUA_STRCO ;  C0M8L4, TRUA_STRE4 ;
DR   B4U545, TRUA_STREM ;  A8AVB3, TRUA_STRGC ;  B1W3X8, TRUA_STRGG ;
DR   B4SQV6, TRUA_STRM5 ;  B2FNZ6, TRUA_STRMK ;  Q8DWH1, TRUA_STRMU ;
DR   P65850, TRUA_STRP1 ;  Q04JF7, TRUA_STRP2 ;  P0DD46, TRUA_STRP3 ;
DR   B5E6N8, TRUA_STRP4 ;  Q5XA03, TRUA_STRP6 ;  C1C8I7, TRUA_STRP7 ;
DR   P65851, TRUA_STRP8 ;  Q1J9W8, TRUA_STRPB ;  Q1JK16, TRUA_STRPC ;
DR   Q1JF09, TRUA_STRPD ;  Q1J4W4, TRUA_STRPF ;  A2RCK6, TRUA_STRPG ;
DR   B1ID11, TRUA_STRPI ;  B8ZM12, TRUA_STRPJ ;  Q48RE4, TRUA_STRPM ;
DR   Q97PL0, TRUA_STRPN ;  P0DD47, TRUA_STRPQ ;  B2IRB1, TRUA_STRPS ;
DR   B5XIG6, TRUA_STRPZ ;  Q8CWQ1, TRUA_STRR6 ;  A4VZC6, TRUA_STRS2 ;
DR   C0MFQ1, TRUA_STRS7 ;  A3CQB8, TRUA_STRSV ;  A4VT40, TRUA_STRSY ;
DR   Q5M1T6, TRUA_STRT1 ;  Q5M6C9, TRUA_STRT2 ;  Q03MR4, TRUA_STRTD ;
DR   B9DTJ0, TRUA_STRU0 ;  C1CFH9, TRUA_STRZJ ;  C1CLU3, TRUA_STRZP ;
DR   C1CSL6, TRUA_STRZT ;  B1XJI2, TRUA_SYNP2 ;  O24712, TRUA_SYNP6 ;
DR   Q7TTT1, TRUA_SYNPX ;  Q3AW68, TRUA_SYNS9 ;  Q3AMQ5, TRUA_SYNSC ;
DR   Q0AUL4, TRUA_SYNWW ;  P73295, TRUA_SYNY3 ;  B7IHS2, TRUA_THEAB ;
DR   Q9HJN5, TRUA_THEAC ;  Q8CWM6, TRUA_THEEB ;  C5A7E9, TRUA_THEGJ ;
DR   A8F526, TRUA_THELT ;  A6LLJ7, TRUA_THEM4 ;  Q9X1R0, TRUA_THEMA ;
DR   B9K8Q0, TRUA_THENN ;  B1YAT9, TRUA_THENV ;  B6YTJ2, TRUA_THEON ;
DR   A5IM09, TRUA_THEP1 ;  B0KCN3, TRUA_THEP3 ;  B0K5S6, TRUA_THEPX ;
DR   C6A238, TRUA_THESM ;  B1LB83, TRUA_THESQ ;  Q72I65, TRUA_THET2 ;
DR   Q5SHU9, TRUA_THET8 ;  Q8R7Y7, TRUA_THETN ;  Q979R4, TRUA_THEVO ;
DR   B5YGE4, TRUA_THEYD ;  Q31HH6, TRUA_THICR ;  Q3SHL7, TRUA_THIDA ;
DR   C4LF13, TRUA_TOLAT ;  Q73KE3, TRUA_TREDE ;  O83802, TRUA_TREPA ;
DR   B2S468, TRUA_TREPS ;  Q820Z2, TRUA_TROW8 ;  Q83G11, TRUA_TROWT ;
DR   Q0W2P8, TRUA_UNCMA ;  B1AJH7, TRUA_UREP2 ;  Q9PPV4, TRUA_UREPA ;
DR   B5ZC44, TRUA_UREU1 ;  C5CSH0, TRUA_VARPS ;  A1WSF3, TRUA_VEREI ;
DR   A5F2T4, TRUA_VIBC3 ;  Q9KTA4, TRUA_VIBCH ;  C3LTP7, TRUA_VIBCM ;
DR   Q5E455, TRUA_VIBF1 ;  B5FFN7, TRUA_VIBFM ;  A7MS76, TRUA_VIBHB ;
DR   Q87MP1, TRUA_VIBPA ;  B7VL84, TRUA_VIBSL ;  Q8CWK3, TRUA_VIBVU ;
DR   Q7M7J4, TRUA_VIBVY ;  Q8D2P5, TRUA_WIGBR ;  Q73G93, TRUA_WOLPM ;
DR   B3CMC1, TRUA_WOLPP ;  Q7M9U3, TRUA_WOLSU ;  C0R4F9, TRUA_WOLWR ;
DR   Q8PJ25, TRUA_XANAC ;  Q3BRL0, TRUA_XANC5 ;  Q4UWD5, TRUA_XANC8 ;
DR   B0RR81, TRUA_XANCB ;  Q8P7R5, TRUA_XANCP ;  Q2P0T9, TRUA_XANOM ;
DR   B2SVP0, TRUA_XANOP ;  Q5GXR2, TRUA_XANOR ;  A7IKI9, TRUA_XANP2 ;
DR   B2I9J0, TRUA_XYLF2 ;  Q9PDK6, TRUA_XYLFA ;  B0U6K4, TRUA_XYLFM ;
DR   Q87DS1, TRUA_XYLFT ;  A7FGM1, TRUA_YERP3 ;  Q8ZD27, TRUA_YERPE ;
DR   Q668W9, TRUA_YERPS ;  Q9REQ0, TRUA_ZYMMO ;
//
ID   5.4.99.13
DE   Isobutyryl-CoA mutase.
CA   2-methylpropanoyl-CoA = butanoyl-CoA.
CF   Cobalt.
//
ID   5.4.99.14
DE   4-carboxymethyl-4-methylbutenolide mutase.
AN   4-methyl-2-enelactone methyl-isomerase.
AN   4-methyl-3-enelactone methyl isomerase.
AN   4-methylmuconolactone methylisomerase.
CA   4-carboxymethyl-4-methylbut-2-en-1,4-olide = 4-carboxymethyl-3-methylbut-
CA   2-en-1,4-olide.
//
ID   5.4.99.15
DE   (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase.
AN   (1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase.
AN   Malto-oligosyltrehalose synthase.
AN   Maltodextrin alpha-D-glucosyltransferase.
CA   4-((1->4)-alpha-D-glucosyl)(n-1)-D-glucose = 1-alpha-D-((1->4)-alpha-D-
CA   glucosyl)(n-1)-alpha-D-glucopyranoside.
CC   -!- Acts on (1->4)-alpha-D-glucans containing three or more (1->4)-alpha-
CC       linked D-glucose units.
CC   -!- Not active toward maltose.
DR   Q44315, TREY_ARTSQ ;  Q10768, TREY_MYCTU ;
//
ID   5.4.99.16
DE   Maltose alpha-D-glucosyltransferase.
AN   Maltose glucosylmutase.
AN   Trehalose synthase.
CA   Maltose = alpha,alpha-trehalose.
DR   A0R6E0, TRES_MYCS2 ;  O07176, TRES_MYCTU ;  P72235, TRES_PIMSR ;
DR   O06458, TRES_THETH ;
//
ID   5.4.99.17
DE   Squalene--hopene cyclase.
CA   (1) Squalene = hop-22(29)-ene.
CA   (2) Squalene + H(2)O = hopan-22-ol.
CC   -!- The enzyme produces a constant ratio of about 5:1 hopene:hopanol.
PR   PROSITE; PDOC00825;
DR   P33247, SQHC_ALIAD ;  Q796C3, SQHC_BACSU ;  P54924, SQHC_BRAJA ;
DR   P55348, SQHC_RHISN ;  P33990, SQHC_ZYMMO ;
//
ID   5.4.99.18
DE   5-(carboxyamino)imidazole ribonucleotide mutase.
AN   N(5)-CAIR mutase.
AN   N(5)-carboxyaminoimidazole ribonucleotide mutase.
CA   5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-
CA   ribosyl)imidazole-4-carboxylate.
CC   -!- In eubacteria, fungi and plants, this enzyme, along with EC 6.3.4.18,
CC       is required to carry out the single reaction catalyzed by EC 4.1.1.21
CC       in vertebrates.
CC   -!- In the absence of EC 6.3.2.6, the reaction is reversible.
CC   -!- The substrate is readily converted into 5-amino-1-(5-phospho-D-
CC       ribosyl)imidazole by non-enzymic decarboxylation.
DR   O67239, PURE_AQUAE ;  O28997, PURE_ARCFU ;  P12044, PURE_BACSU ;
DR   P52558, PURE_BRUME ;  Q8FYW3, PURE_BRUSU ;  Q44679, PURE_CORAM ;
DR   P0AG19, PURE_ECO57 ;  P0AG18, PURE_ECOLI ;  P43849, PURE_HAEIN ;
DR   Q58033, PURE_METJA ;  P22348, PURE_METSM ;  P41654, PURE_METTH ;
DR   P46702, PURE_MYCLE ;  P96880, PURE_MYCTU ;  P72157, PURE_PSEAE ;
DR   Q9UY68, PURE_PYRAB ;  O58058, PURE_PYRHO ;  O06456, PURE_SULSO ;
DR   Q55498, PURE_SYNY3 ;  Q9WYS7, PURE_THEMA ;  Q9KVT7, PURE_VIBCH ;
DR   Q5E1R4, PURE_VIBF1 ;  Q87KE1, PURE_VIBPA ;  Q8DDD7, PURE_VIBVU ;
DR   Q7MGL2, PURE_VIBVY ;
//
ID   5.4.99.19
DE   16S rRNA pseudouridine(516) synthase.
AN   16S RNA pseudouridine 516 synthase.
AN   16S RNA pseudouridine(516) synthase.
AN   16S RNA Psi(516) synthase.
CA   16S rRNA uridine(516) = 16S rRNA pseudouridine(516).
CC   -!- The enzyme is specific for uridine(516) in 16S rRNA.
CC   -!- In vitro, the enzyme does not modify free 16S rRNA.
CC   -!- The preferred substrate is a 5'-terminal fragment of 16S rRNA
CC       complexed with 30S ribosomal proteins.
DR   P0AA45, RSUA_ECO57 ;  P0AA44, RSUA_ECOL6 ;  P0AA43, RSUA_ECOLI ;
DR   P45124, RSUA_HAEIN ;  Q9CPN4, RSUA_PASMU ;  Q9I5J6, RSUA_PSEAE ;
DR   P65841, RSUA_SALTI ;  P65840, RSUA_SALTY ;  P0AA46, RSUA_SHIFL ;
DR   Q9KRK5, RSUA_VIBCH ;  Q87QD4, RSUA_VIBPA ;  Q8D8X2, RSUA_VIBVU ;
DR   Q8ZGM2, RSUA_YERPE ;
//
ID   5.4.99.20
DE   23S rRNA pseudouridine(2457) synthase.
CA   23S rRNA uridine(2457) = 23S rRNA pseudouridine(2457).
CC   -!- The enzyme modifies uridine(2457) in a stem of 23S RNA in Escherichia
CC       coli.
DR   Q8X724, RLUE_ECO57 ;  Q8FIB6, RLUE_ECOL6 ;  P75966, RLUE_ECOLI ;
DR   P44827, RLUE_HAEIN ;  Q9CKK7, RLUE_PASMU ;  Q9HX48, RLUE_PSEAE ;
DR   Q8Z7G6, RLUE_SALTI ;  Q8ZPZ1, RLUE_SALTY ;  Q83LF6, RLUE_SHIFL ;
DR   Q9F855, RLUE_VIBCH ;  Q87QY8, RLUE_VIBPA ;  Q8DAS3, RLUE_VIBVU ;
DR   Q8PQN3, RLUE_XANAC ;  Q8PDR2, RLUE_XANCP ;  Q8ZFQ3, RLUE_YERPE ;
//
ID   5.4.99.21
DE   23S rRNA pseudouridine(2604) synthase.
CA   23S rRNA uridine(2604) = 23S rRNA pseudouridine(2604).
CC   -!- The enzyme is not completely specific for uridine(2604) and can, to a
CC       small extent, also react with uridine(2605).
DR   P32684, RLUF_ECOLI ;
//
ID   5.4.99.22
DE   23S rRNA pseudouridine(2605) synthase.
CA   23S rRNA uridine(2605) = 23S rRNA pseudouridine(2605).
CC   -!- Pseudouridine synthase RluB converts uridine(2605) of 23S rRNA to
CC       pseudouridine.
DR   P35159, RLUB_BACSU ;  P57369, RLUB_BUCAI ;  P42395, RLUB_BUCAP ;
DR   Q89AL1, RLUB_BUCBP ;  Q8X4Q8, RLUB_ECO57 ;  Q8FHV4, RLUB_ECOL6 ;
DR   P37765, RLUB_ECOLI ;  P45104, RLUB_HAEIN ;  Q9CMY9, RLUB_PASMU ;
DR   Q9HZ55, RLUB_PSEAE ;  Q8Z7D5, RLUB_SALTI ;  Q8ZP51, RLUB_SALTY ;
DR   P59815, RLUB_SHIFL ;  Q9KSS7, RLUB_VIBCH ;  Q87NB7, RLUB_VIBPA ;
DR   Q8D8C0, RLUB_VIBVU ;  Q8PK58, RLUB_XANAC ;  Q8P8M6, RLUB_XANCP ;
DR   Q9PAP2, RLUB_XYLFA ;  Q87BI2, RLUB_XYLFT ;  Q8ZEG0, RLUB_YERPE ;
//
ID   5.4.99.23
DE   23S rRNA pseudouridine(1911/1915/1917) synthase.
CA   23S rRNA uridine(1911)/uridine(1915)/uridine(1917) = 23S rRNA
CA   pseudouridine(1911)/pseudouridine(1915)/pseudouridine(1917).
CC   -!- Pseudouridine synthase RluD converts uridines at positions 1911,
CC       1915, and 1917 of 23S rRNA to pseudouridines.
CC   -!- These nucleotides are located in the functionally important helix-
CC       loop 69 of 23S rRNA.
DR   P59838, RLUD_BLOFL ;  P70870, RLUD_BORBU ;  P57481, RLUD_BUCAI ;
DR   Q8K9E9, RLUD_BUCAP ;  Q89AD9, RLUD_BUCBP ;  Q8X9F0, RLUD_ECO57 ;
DR   P65834, RLUD_ECOL6 ;  P33643, RLUD_ECOLI ;  Q9L7A7, RLUD_HAEDU ;
DR   P44445, RLUD_HAEIN ;  Q9JVB6, RLUD_NEIMA ;  Q9K0B0, RLUD_NEIMB ;
DR   Q82WZ5, RLUD_NITEU ;  Q9CKA6, RLUD_PASMU ;  P33640, RLUD_PSEAE ;
DR   Q8XYX8, RLUD_RALSO ;  P65837, RLUD_SALTI ;  P65836, RLUD_SALTY ;
DR   P65835, RLUD_SHIFL ;  Q9KU20, RLUD_VIBCH ;  Q87S65, RLUD_VIBPA ;
DR   Q8DEV0, RLUD_VIBVU ;  Q8PHN2, RLUD_XANAC ;  Q8P682, RLUD_XANCP ;
DR   Q9PET9, RLUD_XYLFA ;  Q87AR7, RLUD_XYLFT ;  Q8ZBV7, RLUD_YERPE ;
DR   P50513, RLUD_ZYMMO ;
//
ID   5.4.99.24
DE   23S rRNA pseudouridine(955/2504/2580) synthase.
CA   23S rRNA uridine(955)/uridine(2504)/uridine(2580) = 23S rRNA
CA   pseudouridine(955)/pseudouridine(2504)/pseudouridine(2580).
CC   -!- The enzyme converts uridines at position 955, 2504 and 2580 of 23S
CC       rRNA to pseudouridines.
DR   P57430, RLUC_BUCAI ;  Q8K9J8, RLUC_BUCAP ;  Q89AH2, RLUC_BUCBP ;
DR   Q8X8J3, RLUC_ECO57 ;  Q8FIP7, RLUC_ECOL6 ;  P0AA39, RLUC_ECOLI ;
DR   P59835, RLUC_HAEDU ;  P44433, RLUC_HAEIN ;  Q9CM51, RLUC_PASMU ;
DR   Q9HZM9, RLUC_PSEAE ;  Q1RJX7, RLUC_RICBR ;  Q92IS6, RLUC_RICCN ;
DR   Q4UKQ3, RLUC_RICFE ;  Q9ZDR7, RLUC_RICPR ;  Q68XB2, RLUC_RICTY ;
DR   Q8Z7J7, RLUC_SALTI ;  Q8ZQ16, RLUC_SALTY ;  P0AA40, RLUC_SHIFL ;
DR   Q9KQH0, RLUC_VIBCH ;  Q87N15, RLUC_VIBPA ;  Q8D8G1, RLUC_VIBVU ;
DR   Q8ZFU1, RLUC_YERPE ;
//
ID   5.4.99.25
DE   tRNA pseudouridine(55) synthase.
AN   Psi(55) synthase.
AN   Psi(55) tRNA pseudouridine synthase.
AN   tRNA pseudouridine 55 synthase.
AN   tRNA Psi(55) synthase.
CA   tRNA uridine(55) = tRNA pseudouridine(55).
CC   -!- Pseudourine synthase TruB from Escherichia coli specifically modifies
CC       uridine tRNA pseudouridine 55 synthase in tRNA molecules.
DR   O59721, PUS4_SCHPO ;  P48567, PUS4_YEAST ;  B0CCH1, TRUB_ACAM1 ;
DR   A9NGE6, TRUB_ACHLI ;  Q6F7I5, TRUB_ACIAD ;  A3N007, TRUB_ACTP2 ;
DR   A6VNE2, TRUB_ACTSZ ;  Q9YDC3, TRUB_AERPE ;  A4SJR7, TRUB_AERS4 ;
DR   Q8UJ53, TRUB_AGRT5 ;  B6ENE4, TRUB_ALISL ;  A8MFB1, TRUB_ALKOO ;
DR   Q5PAY2, TRUB_ANAMM ;  Q2GJV3, TRUB_ANAPZ ;  Q3M356, TRUB_ANAVT ;
DR   O66922, TRUB_AQUAE ;  O30001, TRUB_ARCFU ;  Q5NZR9, TRUB_AROAE ;
DR   A1R520, TRUB_ARTAT ;  A0JUU8, TRUB_ARTS2 ;  Q2NIZ2, TRUB_AYWBP ;
DR   A1K7B7, TRUB_AZOSB ;  A7Z4T7, TRUB_BACA2 ;  A0RHI1, TRUB_BACAH ;
DR   P59873, TRUB_BACAN ;  Q732R2, TRUB_BACC1 ;  A7GRE0, TRUB_BACCN ;
DR   Q812X9, TRUB_BACCR ;  Q636L6, TRUB_BACCZ ;  Q5LJ29, TRUB_BACFN ;
DR   Q650L8, TRUB_BACFR ;  Q9KA80, TRUB_BACHD ;  Q6HF05, TRUB_BACHK ;
DR   Q65JH8, TRUB_BACLD ;  A8FDD4, TRUB_BACP2 ;  Q5WFU5, TRUB_BACSK ;
DR   P32732, TRUB_BACSU ;  Q8A2U2, TRUB_BACTN ;  A6KZJ9, TRUB_BACV8 ;
DR   A1UU52, TRUB_BARBK ;  Q6G5F5, TRUB_BARHE ;  Q6G0P4, TRUB_BARQU ;
DR   A9IMS8, TRUB_BART1 ;  Q1LSL0, TRUB_BAUCH ;  Q6MMS4, TRUB_BDEBA ;
DR   B3DQF2, TRUB_BIFLD ;  Q8CY45, TRUB_BIFLO ;  B7GNA1, TRUB_BIFLS ;
DR   P59877, TRUB_BLOFL ;  Q493T5, TRUB_BLOPB ;  Q2KXZ0, TRUB_BORA1 ;
DR   Q0SM48, TRUB_BORAP ;  P65853, TRUB_BORBR ;  O51743, TRUB_BORBU ;
DR   B7J0P9, TRUB_BORBZ ;  Q65ZX0, TRUB_BORGA ;  P59874, TRUB_BORPA ;
DR   P65852, TRUB_BORPE ;  Q89WB1, TRUB_BRAJA ;  Q2YQR5, TRUB_BRUA2 ;
DR   Q57A98, TRUB_BRUAB ;  A9M9Z6, TRUB_BRUC2 ;  Q8YEB5, TRUB_BRUME ;
DR   A5VTB4, TRUB_BRUO2 ;  B0CK13, TRUB_BRUSI ;  P59876, TRUB_BRUSU ;
DR   P57456, TRUB_BUCAI ;  Q8K9H3, TRUB_BUCAP ;  Q89AF6, TRUB_BUCBP ;
DR   A3MJW6, TRUB_BURM7 ;  Q62KL1, TRUB_BURMA ;  A3NUL2, TRUB_BURP0 ;
DR   Q3JSY7, TRUB_BURP1 ;  A3N8W0, TRUB_BURP6 ;  Q63TQ0, TRUB_BURPS ;
DR   Q39H28, TRUB_BURS3 ;  A4XL67, TRUB_CALS8 ;  A7ZE50, TRUB_CAMC1 ;
DR   A7GZ93, TRUB_CAMC5 ;  A8FMF5, TRUB_CAMJ8 ;  A7H2Q5, TRUB_CAMJD ;
DR   Q9PNJ2, TRUB_CAMJE ;  A1W089, TRUB_CAMJJ ;  Q5HU02, TRUB_CAMJR ;
DR   Q3ABA1, TRUB_CARHZ ;  P58063, TRUB_CAUCR ;  B0T173, TRUB_CAUSK ;
DR   Q5L629, TRUB_CHLAB ;  Q3AQK9, TRUB_CHLCH ;  Q254H2, TRUB_CHLFF ;
DR   Q9PKU2, TRUB_CHLMU ;  Q9Z8L9, TRUB_CHLPN ;  B0B9K2, TRUB_CHLT2 ;
DR   B3QZ05, TRUB_CHLT3 ;  B0BB81, TRUB_CHLTB ;  Q8KFS9, TRUB_CHLTE ;
DR   O84096, TRUB_CHLTR ;  Q1QSZ2, TRUB_CHRSD ;  Q7MBF7, TRUB_CHRVO ;
DR   A8AQ55, TRUB_CITK8 ;  Q97I48, TRUB_CLOAB ;  A7GG03, TRUB_CLOBL ;
DR   Q18BH7, TRUB_CLOD6 ;  A5N845, TRUB_CLOK5 ;  A0Q0Q4, TRUB_CLONN ;
DR   Q0TPS0, TRUB_CLOP1 ;  Q8XJS1, TRUB_CLOPE ;  A9KNW1, TRUB_CLOPH ;
DR   Q0SSD7, TRUB_CLOPS ;  Q895J5, TRUB_CLOTE ;  Q482T7, TRUB_COLP3 ;
DR   C3PH13, TRUB_CORA7 ;  P60343, TRUB_CORDI ;  Q8FPB3, TRUB_COREF ;
DR   A4QEY6, TRUB_CORGB ;  Q8NP46, TRUB_CORGL ;  Q4JV56, TRUB_CORJK ;
DR   A9KBM3, TRUB_COXBN ;  A9N8V4, TRUB_COXBR ;  Q4AAX7, TRUB_COXBU ;
DR   Q46ZP3, TRUB_CUPPJ ;  B3R1E2, TRUB_CUPTR ;  B7KGX7, TRUB_CYAP7 ;
DR   Q47D96, TRUB_DECAR ;  Q3Z7U5, TRUB_DEHE1 ;  A5FQR4, TRUB_DEHSB ;
DR   Q3ZXU5, TRUB_DEHSC ;  C1D1L3, TRUB_DEIDV ;  Q1J0C1, TRUB_DEIGD ;
DR   Q9RUQ9, TRUB_DEIRA ;  Q30WI7, TRUB_DESDG ;  Q6AJY7, TRUB_DESPS ;
DR   Q72ER4, TRUB_DESVH ;  B8DN09, TRUB_DESVM ;  A8LL26, TRUB_DINSH ;
DR   A7ZS63, TRUB_ECO24 ;  P60342, TRUB_ECO57 ;  A8A4Y2, TRUB_ECOHS ;
DR   A1AG71, TRUB_ECOK1 ;  Q0TCU3, TRUB_ECOL5 ;  P60341, TRUB_ECOL6 ;
DR   B1IQV5, TRUB_ECOLC ;  P60340, TRUB_ECOLI ;  Q1R6H2, TRUB_ECOUT ;
DR   Q3YSC6, TRUB_EHRCJ ;  Q2GGA2, TRUB_EHRCR ;  Q5FHK7, TRUB_EHRRG ;
DR   Q5HBH8, TRUB_EHRRW ;  A4WEY1, TRUB_ENT38 ;  A7MQD9, TRUB_ENTS8 ;
DR   Q6D9A3, TRUB_ERWCT ;  Q9RB36, TRUB_FLAJ1 ;  B0TXH9, TRUB_FRAP2 ;
DR   Q14G67, TRUB_FRAT1 ;  A7NAR1, TRUB_FRATF ;  Q2A4N1, TRUB_FRATH ;
DR   A0Q7W5, TRUB_FRATN ;  Q0BN06, TRUB_FRATO ;  Q5NER4, TRUB_FRATT ;
DR   A4IWL0, TRUB_FRATW ;  Q8R5X8, TRUB_FUSNN ;  Q5L0I5, TRUB_GEOKA ;
DR   Q39VA3, TRUB_GEOMG ;  P60344, TRUB_GEOSL ;  A4IME0, TRUB_GEOTN ;
DR   A5GF89, TRUB_GEOUR ;  Q7MBB8, TRUB_GLOVI ;  A9HF26, TRUB_GLUDA ;
DR   Q5FQM1, TRUB_GLUOX ;  P59878, TRUB_HAEDU ;  Q4QK43, TRUB_HAEI8 ;
DR   A5UBU2, TRUB_HAEIE ;  A5UF28, TRUB_HAEIG ;  P45142, TRUB_HAEIN ;
DR   Q0I3P3, TRUB_HAES1 ;  B0UU15, TRUB_HAES2 ;  Q2SML1, TRUB_HAHCH ;
DR   A1WXU9, TRUB_HALHL ;  Q5UXH1, TRUB_HALMA ;  B0R686, TRUB_HALS3 ;
DR   Q9HPA4, TRUB_HALSA ;  C4K3E8, TRUB_HAMD5 ;  Q7U330, TRUB_HELHP ;
DR   B0THR7, TRUB_HELMI ;  Q8GB99, TRUB_HELMO ;  Q5QTZ0, TRUB_IDILO ;
DR   Q28K11, TRUB_JANSC ;  A6TEI5, TRUB_KLEP7 ;  B1L793, TRUB_KORCO ;
DR   Q5FJN8, TRUB_LACAC ;  Q03QT7, TRUB_LACBA ;  Q038M8, TRUB_LACC3 ;
DR   B3WER2, TRUB_LACCB ;  Q1G9Q1, TRUB_LACDA ;  Q049V7, TRUB_LACDB ;
DR   Q044B5, TRUB_LACGA ;  Q74IT0, TRUB_LACJO ;  Q9CGH0, TRUB_LACLA ;
DR   A2RL47, TRUB_LACLM ;  Q02Z55, TRUB_LACLS ;  Q88VL5, TRUB_LACPL ;
DR   A5VJE2, TRUB_LACRD ;  Q1WUF2, TRUB_LACS1 ;  Q38W87, TRUB_LACSS ;
DR   Q5X1C5, TRUB_LEGPA ;  A5IHU5, TRUB_LEGPC ;  Q5ZRV6, TRUB_LEGPH ;
DR   Q5WT38, TRUB_LEGPL ;  Q6AG41, TRUB_LEIXX ;  Q72NX5, TRUB_LEPIC ;
DR   Q8CXU1, TRUB_LEPIN ;  Q92C26, TRUB_LISIN ;  Q71ZZ4, TRUB_LISMF ;
DR   Q8Y7F3, TRUB_LISMO ;  A0AIC9, TRUB_LISW6 ;  Q65SL2, TRUB_MANSM ;
DR   A1U5Z8, TRUB_MARAV ;  Q0AK64, TRUB_MARMM ;  A6VU31, TRUB_MARMS ;
DR   Q6F1I4, TRUB_MESFL ;  Q11BC6, TRUB_MESSB ;  A6UWC6, TRUB_META3 ;
DR   Q8TRR5, TRUB_METAC ;  Q46GC3, TRUB_METBF ;  Q609C2, TRUB_METCA ;
DR   Q1GXD4, TRUB_METFK ;  Q57612, TRUB_METJA ;  Q8TZ08, TRUB_METKA ;
DR   A4G0N3, TRUB_METM5 ;  A9A8X7, TRUB_METM6 ;  A6VHV2, TRUB_METM7 ;
DR   Q8PV20, TRUB_METMA ;  Q6LWM3, TRUB_METMP ;  O26140, TRUB_METTH ;
DR   B0JJJ5, TRUB_MICAN ;  Q2RJM2, TRUB_MOOTA ;  A0QIX1, TRUB_MYCA1 ;
DR   B1MD72, TRUB_MYCA9 ;  P62189, TRUB_MYCBO ;  A1KMD6, TRUB_MYCBP ;
DR   Q2SSF2, TRUB_MYCCT ;  P59879, TRUB_MYCGA ;  Q601U7, TRUB_MYCH2 ;
DR   Q9Z5I4, TRUB_MYCLE ;  Q6KHH8, TRUB_MYCMO ;  Q6MTR0, TRUB_MYCMS ;
DR   Q73VW3, TRUB_MYCPA ;  Q8CXQ2, TRUB_MYCPE ;  Q98Q19, TRUB_MYCPU ;
DR   A3PY88, TRUB_MYCSJ ;  A1UET1, TRUB_MYCSK ;  Q1BA81, TRUB_MYCSS ;
DR   A5U6E6, TRUB_MYCTA ;  P62190, TRUB_MYCTU ;  A0PQD9, TRUB_MYCUA ;
DR   P60346, TRUB_NANEQ ;  Q5F8W8, TRUB_NEIG1 ;  B4RMB1, TRUB_NEIG2 ;
DR   Q9JTX5, TRUB_NEIMA ;  Q9JYY1, TRUB_NEIMB ;  Q820P2, TRUB_NITEU ;
DR   Q2Y7W4, TRUB_NITMU ;  Q3J9B8, TRUB_NITOC ;  A6Q522, TRUB_NITSB ;
DR   Q3SWP7, TRUB_NITWN ;  Q5YSE0, TRUB_NOCFA ;  Q8YWR1, TRUB_NOSS1 ;
DR   Q2G5F3, TRUB_NOVAD ;  Q8CXG9, TRUB_OCEIH ;  A6WWW3, TRUB_OCHA4 ;
DR   Q04ED7, TRUB_OENOB ;  Q6YQY6, TRUB_ONYPE ;  B1ZX46, TRUB_OPITP ;
DR   A6LEL7, TRUB_PARD8 ;  A1B5U1, TRUB_PARDP ;  Q6MD66, TRUB_PARUW ;
DR   Q9CMQ7, TRUB_PASMU ;  Q03FS1, TRUB_PEDPA ;  Q3A4A3, TRUB_PELCD ;
DR   Q3B200, TRUB_PELLD ;  A5D2S3, TRUB_PELTS ;  Q7MAY1, TRUB_PHOLL ;
DR   Q6LUJ0, TRUB_PHOPR ;  Q6L1A0, TRUB_PICTO ;  Q6A7P0, TRUB_PROAC ;
DR   A3PEI1, TRUB_PROM0 ;  A2C4C0, TRUB_PROM1 ;  A8G6F8, TRUB_PROM2 ;
DR   A2BY54, TRUB_PROM5 ;  Q319E0, TRUB_PROM9 ;  P59880, TRUB_PROMA ;
DR   P59881, TRUB_PROMM ;  P59882, TRUB_PROMP ;  A2BSS0, TRUB_PROMS ;
DR   Q46JB9, TRUB_PROMT ;  A4SGG0, TRUB_PROVI ;  Q48E79, TRUB_PSE14 ;
DR   Q15V70, TRUB_PSEA6 ;  A6VCJ9, TRUB_PSEA7 ;  Q02FT0, TRUB_PSEAB ;
DR   P72154, TRUB_PSEAE ;  Q1IF41, TRUB_PSEE4 ;  Q4KIF4, TRUB_PSEF5 ;
DR   Q3IJ75, TRUB_PSEHT ;  A4XYD8, TRUB_PSEMY ;  A5W985, TRUB_PSEP1 ;
DR   Q3KI82, TRUB_PSEPF ;  B0KHX6, TRUB_PSEPG ;  Q4ZNR4, TRUB_PSEU2 ;
DR   A4VPN8, TRUB_PSEU5 ;  Q4FVL3, TRUB_PSYA2 ;  Q1QEP3, TRUB_PSYCK ;
DR   A1ST47, TRUB_PSYIN ;  Q9V1A5, TRUB_PYRAB ;  Q8ZYB3, TRUB_PYRAE ;
DR   A4WH37, TRUB_PYRAR ;  A3MS77, TRUB_PYRCJ ;  Q7LWY0, TRUB_PYRFU ;
DR   O59357, TRUB_PYRHO ;  A1RTL7, TRUB_PYRIL ;  Q5JJE8, TRUB_PYRKO ;
DR   Q1LLR8, TRUB_RALME ;  B2UAA5, TRUB_RALPJ ;  Q8XZV4, TRUB_RALSO ;
DR   Q2KDZ7, TRUB_RHIEC ;  Q1MN41, TRUB_RHIL3 ;  Q98BI6, TRUB_RHILO ;
DR   Q92SW2, TRUB_RHIME ;  P59883, TRUB_RHOBA ;  P60345, TRUB_RHOPA ;
DR   Q2RMR8, TRUB_RHORT ;  A3PNF6, TRUB_RHOS1 ;  Q3IYU1, TRUB_RHOS4 ;
DR   A4WWP4, TRUB_RHOS5 ;  Q0S212, TRUB_RHOSR ;  C3PNK4, TRUB_RICAE ;
DR   A8GNM0, TRUB_RICAH ;  A8GWV0, TRUB_RICB8 ;  Q1RIG2, TRUB_RICBR ;
DR   A8EYU0, TRUB_RICCK ;  Q92HV5, TRUB_RICCN ;  Q4ULJ9, TRUB_RICFE ;
DR   Q9ZD46, TRUB_RICPR ;  C4K0F2, TRUB_RICPU ;  B0BXR2, TRUB_RICRO ;
DR   A8GS98, TRUB_RICRS ;  Q68WN3, TRUB_RICTY ;  Q16CE8, TRUB_ROSDO ;
DR   Q21H63, TRUB_SACD2 ;  A9MP38, TRUB_SALAR ;  Q57JI1, TRUB_SALCH ;
DR   Q5PLB2, TRUB_SALPA ;  A9N730, TRUB_SALPB ;  Q8Z3H9, TRUB_SALTI ;
DR   Q8ZLT2, TRUB_SALTY ;  A8G909, TRUB_SERP5 ;  A1S464, TRUB_SHEAM ;
DR   B8E6N4, TRUB_SHEB2 ;  A3D7K4, TRUB_SHEB5 ;  A6WRG6, TRUB_SHEB8 ;
DR   A9KZW9, TRUB_SHEB9 ;  Q12QH9, TRUB_SHEDO ;  Q086H0, TRUB_SHEFN ;
DR   B0TQA0, TRUB_SHEHH ;  A3QGU3, TRUB_SHELP ;  A8H738, TRUB_SHEPA ;
DR   A4Y9B8, TRUB_SHEPC ;  B8CKH5, TRUB_SHEPW ;  A0KTZ8, TRUB_SHESA ;
DR   Q0HLF9, TRUB_SHESM ;  Q0HXR3, TRUB_SHESR ;  A1RGX7, TRUB_SHESW ;
DR   B1KRQ8, TRUB_SHEWM ;  Q31W45, TRUB_SHIBS ;  Q32BG7, TRUB_SHIDS ;
DR   Q0T0B5, TRUB_SHIF8 ;  Q83MJ8, TRUB_SHIFL ;  Q3YX75, TRUB_SHISS ;
DR   Q5LLT4, TRUB_SILPO ;  Q1GKJ9, TRUB_SILST ;  A6UF31, TRUB_SINMW ;
DR   Q2NW21, TRUB_SODGM ;  Q01SZ5, TRUB_SOLUE ;  A7X1Q5, TRUB_STAA1 ;
DR   A6U190, TRUB_STAA2 ;  Q2FHG7, TRUB_STAA3 ;  Q2G2Q3, TRUB_STAA8 ;
DR   A5ISF5, TRUB_STAA9 ;  Q2YXP5, TRUB_STAAB ;  Q5HGG0, TRUB_STAAC ;
DR   A6QGH0, TRUB_STAAE ;  P65854, TRUB_STAAM ;  P65855, TRUB_STAAN ;
DR   Q6GHG4, TRUB_STAAR ;  Q6G9U2, TRUB_STAAS ;  A8Z3V1, TRUB_STAAT ;
DR   Q8NWZ0, TRUB_STAAW ;  Q5HPS0, TRUB_STAEQ ;  Q8CMM6, TRUB_STAES ;
DR   Q4L5X4, TRUB_STAHJ ;  Q49X59, TRUB_STAS1 ;  Q3K189, TRUB_STRA1 ;
DR   P65856, TRUB_STRA3 ;  P65857, TRUB_STRA5 ;  Q82K56, TRUB_STRAW ;
DR   Q9Z528, TRUB_STRCO ;  A8AX28, TRUB_STRGC ;  B1VYN2, TRUB_STRGG ;
DR   Q8DU15, TRUB_STRMU ;  P65858, TRUB_STRP1 ;  Q04KA7, TRUB_STRP2 ;
DR   P0DD48, TRUB_STRP3 ;  Q5XBX7, TRUB_STRP6 ;  P65859, TRUB_STRP8 ;
DR   Q1JBI5, TRUB_STRPB ;  Q1JLG7, TRUB_STRPC ;  Q1JGK3, TRUB_STRPD ;
DR   Q1J6C1, TRUB_STRPF ;  A2RE90, TRUB_STRPG ;  Q48TB3, TRUB_STRPM ;
DR   Q97QJ3, TRUB_STRPN ;  P0DD49, TRUB_STRPQ ;  Q8CWR2, TRUB_STRR6 ;
DR   A3CMF2, TRUB_STRSV ;  Q5LZV2, TRUB_STRT1 ;  Q5M4G2, TRUB_STRT2 ;
DR   Q30TG2, TRUB_SULDN ;  A6Q784, TRUB_SULNB ;  Q980C3, TRUB_SULSO ;
DR   Q975L5, TRUB_SULTO ;  Q67P83, TRUB_SYMTH ;  Q2LWU1, TRUB_SYNAS ;
DR   Q8KIY0, TRUB_SYNE7 ;  A0LHM2, TRUB_SYNFM ;  Q5N5A0, TRUB_SYNP6 ;
DR   A5GN82, TRUB_SYNPW ;  P59884, TRUB_SYNPX ;  Q0I7Z1, TRUB_SYNS3 ;
DR   Q0AYI5, TRUB_SYNWW ;  P74696, TRUB_SYNY3 ;  Q9HIT4, TRUB_THEAC ;
DR   Q8CWM3, TRUB_THEEB ;  Q47RU8, TRUB_THEFY ;  C5A255, TRUB_THEGJ ;
DR   A6LLV6, TRUB_THEM4 ;  Q9WZW0, TRUB_THEMA ;  B1YA64, TRUB_THENV ;
DR   B6YSP4, TRUB_THEON ;  A5IIS7, TRUB_THEP1 ;  Q72GS9, TRUB_THET2 ;
DR   Q5SLS6, TRUB_THET8 ;  Q8RA40, TRUB_THETN ;  Q97BU9, TRUB_THEVO ;
DR   Q31GK3, TRUB_THICR ;  Q3SKX3, TRUB_THIDA ;  C4L8X2, TRUB_TOLAT ;
DR   Q73NP8, TRUB_TREDE ;  O83859, TRUB_TREPA ;  B2S4C6, TRUB_TREPS ;
DR   Q112N2, TRUB_TRIEI ;  Q820Z5, TRUB_TROW8 ;  Q820Y5, TRUB_TROWT ;
DR   B1GZN9, TRUB_UNCTG ;  B1AIZ3, TRUB_UREP2 ;  Q9PQD7, TRUB_UREPA ;
DR   B5ZBG4, TRUB_UREU1 ;  A1WLI1, TRUB_VEREI ;  A5F928, TRUB_VIBC3 ;
DR   Q9KU78, TRUB_VIBCH ;  C3LSQ0, TRUB_VIBCM ;  Q5E7L3, TRUB_VIBF1 ;
DR   B5FA81, TRUB_VIBFM ;  A7MZI3, TRUB_VIBHB ;  Q87M04, TRUB_VIBPA ;
DR   B7VJH5, TRUB_VIBSL ;  Q8DBV8, TRUB_VIBVU ;  Q7MI11, TRUB_VIBVY ;
DR   Q8D2X8, TRUB_WIGBR ;  B3CM19, TRUB_WOLPP ;  Q7M9J1, TRUB_WOLSU ;
DR   Q8PJ57, TRUB_XANAC ;  Q3BRP7, TRUB_XANC5 ;  Q4UWA0, TRUB_XANC8 ;
DR   B0RRB6, TRUB_XANCB ;  Q8P7U9, TRUB_XANCP ;  Q2P0X3, TRUB_XANOM ;
DR   Q5GXV1, TRUB_XANOR ;  Q9PGR1, TRUB_XYLFA ;  Q87EV2, TRUB_XYLFT ;
DR   A1JIX1, TRUB_YERE8 ;  O34273, TRUB_YEREN ;  A7FMS0, TRUB_YERP3 ;
DR   Q1CC09, TRUB_YERPA ;  Q8ZBC4, TRUB_YERPE ;  Q1CEL5, TRUB_YERPN ;
DR   A4TRI1, TRUB_YERPP ;  Q66F58, TRUB_YERPS ;  Q5NQ30, TRUB_ZYMMO ;
//
ID   5.4.99.26
DE   tRNA pseudouridine(65) synthase.
CA   tRNA uridine(65) = tRNA pseudouridine(65).
CC   -!- TruC specifically modifies uridines at positions 65 in tRNA.
DR   Q8X6T6, TRUC_ECO57 ;  Q8FEF9, TRUC_ECOL6 ;  P0AA41, TRUC_ECOLI ;
DR   P59840, TRUC_HAEDU ;  P44197, TRUC_HAEIN ;  Q9CNF3, TRUC_PASMU ;
DR   Q47417, TRUC_PECCC ;  Q8Z439, TRUC_SALTI ;  Q8ZMD5, TRUC_SALTY ;
DR   P0AA42, TRUC_SHIFL ;  Q9KTL4, TRUC_VIBCH ;  Q87MD4, TRUC_VIBPA ;
DR   Q8DBG5, TRUC_VIBVU ;  Q8ZH72, TRUC_YERPE ;
//
ID   5.4.99.27
DE   tRNA pseudouridine(13) synthase.
AN   tRNA Psi(13) synthase.
CA   tRNA uridine(13) = tRNA pseudouridine(13).
CC   -!- Pseudouridine synthase PusS from Escherichia coli specifically acts
CC       on uridine(13) in tRNA.
CC   -!- The Pus7 protein from Saccharomyces cerevisiae is a multisite-
CC       multisubstrate pseudouridine synthase that is able to modify
CC       uridine(13) in several yeast tRNAs, uridine(35) in the pre-tRNA(Tyr),
CC       uridine(35) in U2 small nuclear RNA, and uridine(50) in 5S rRNA.
DR   Q08647, PUS7_YEAST ;  Q58008, TRUD1_METJA;  Q6M1A3, TRUD1_METMP;
DR   Q58759, TRUD2_METJA;  Q6LZL0, TRUD2_METMP;  A6VR02, TRUD_ACTSZ ;
DR   A0KGH7, TRUD_AERHH ;  A4SRB7, TRUD_AERS4 ;  B6EKL4, TRUD_ALISL ;
DR   B8J7C8, TRUD_ANAD2 ;  Q2IFQ4, TRUD_ANADE ;  A7HGV2, TRUD_ANADF ;
DR   O67616, TRUD_AQUAE ;  O28596, TRUD_ARCFU ;  C1DSR9, TRUD_AZOVD ;
DR   A8FNC4, TRUD_CAMJ8 ;  A7H5G6, TRUD_CAMJD ;  Q9PMK3, TRUD_CAMJE ;
DR   A1W165, TRUD_CAMJJ ;  Q5HSX3, TRUD_CAMJR ;  B3PJA9, TRUD_CELJU ;
DR   Q1QU75, TRUD_CHRSD ;  A8ANV9, TRUD_CITK8 ;  Q487E7, TRUD_COLP3 ;
DR   Q9RSX8, TRUD_DEIRA ;  A7ZQI9, TRUD_ECO24 ;  B7UHG4, TRUD_ECO27 ;
DR   B7MKL9, TRUD_ECO45 ;  B7LEG3, TRUD_ECO55 ;  Q8X7Y6, TRUD_ECO57 ;
DR   B5Z3A7, TRUD_ECO5E ;  B7NT89, TRUD_ECO7I ;  B7MZ46, TRUD_ECO81 ;
DR   B7LXF7, TRUD_ECO8A ;  C4ZZP9, TRUD_ECOBW ;  B1XCS1, TRUD_ECODH ;
DR   A8A3M4, TRUD_ECOHS ;  A1AET9, TRUD_ECOK1 ;  Q0TEB3, TRUD_ECOL5 ;
DR   Q8FEJ7, TRUD_ECOL6 ;  B1IUT4, TRUD_ECOLC ;  Q57261, TRUD_ECOLI ;
DR   B7N6X5, TRUD_ECOLU ;  B6I6D5, TRUD_ECOSE ;  B1LQ65, TRUD_ECOSM ;
DR   Q1R7U6, TRUD_ECOUT ;  C5BGI9, TRUD_EDWI9 ;  A4WDV0, TRUD_ENT38 ;
DR   A7MJ59, TRUD_ENTS8 ;  Q6D1B5, TRUD_ERWCT ;  B2VFZ5, TRUD_ERWT9 ;
DR   B7LWL0, TRUD_ESCF3 ;  Q39R76, TRUD_GEOMG ;  B9M644, TRUD_GEOSF ;
DR   P60347, TRUD_GEOSL ;  C6E4K4, TRUD_GEOSM ;  Q4QML9, TRUD_HAEI8 ;
DR   A5UE25, TRUD_HAEIE ;  P44039, TRUD_HAEIN ;  Q0I5H8, TRUD_HAES1 ;
DR   B0URU7, TRUD_HAES2 ;  Q5V1E6, TRUD_HALMA ;  B0R2Y4, TRUD_HALS3 ;
DR   Q9HSG5, TRUD_HALSA ;  Q17WX3, TRUD_HELAH ;  P59892, TRUD_HELHP ;
DR   B6JME7, TRUD_HELP2 ;  B5Z7T0, TRUD_HELPG ;  Q1CSU8, TRUD_HELPH ;
DR   Q9ZKS5, TRUD_HELPJ ;  B2UU74, TRUD_HELPS ;  P55985, TRUD_HELPY ;
DR   Q5QUC5, TRUD_IDILO ;  B5XV36, TRUD_KLEP3 ;  A6TD37, TRUD_KLEP7 ;
DR   Q5X4T2, TRUD_LEGPA ;  A5ICB9, TRUD_LEGPC ;  Q5ZV19, TRUD_LEGPH ;
DR   Q5WWQ2, TRUD_LEGPL ;  Q72N01, TRUD_LEPIC ;  Q8F8N2, TRUD_LEPIN ;
DR   Q65Q80, TRUD_MANSM ;  A1TZ52, TRUD_MARAV ;  A6UV17, TRUD_META3 ;
DR   Q8TKX2, TRUD_METAC ;  Q466V2, TRUD_METBF ;  Q12WH6, TRUD_METBU ;
DR   Q604M0, TRUD_METCA ;  Q8TXJ7, TRUD_METKA ;  A4FYL2, TRUD_METM5 ;
DR   Q8Q0M2, TRUD_METMA ;  O27572, TRUD_METTH ;  A6USB0, TRUD_METVS ;
DR   P60348, TRUD_NANEQ ;  Q3IMF3, TRUD_NATPD ;  Q3JCS7, TRUD_NITOC ;
DR   A6Q2U7, TRUD_NITSB ;  Q9CKK4, TRUD_PASMU ;  C6DDG0, TRUD_PECCP ;
DR   Q3A6I8, TRUD_PELCD ;  Q7N8K5, TRUD_PHOLL ;  Q6LMT5, TRUD_PHOPR ;
DR   Q6L1R2, TRUD_PICTO ;  B4F225, TRUD_PROMH ;  Q48F86, TRUD_PSE14 ;
DR   Q15P29, TRUD_PSEA6 ;  A6V1G2, TRUD_PSEA7 ;  B7V8C2, TRUD_PSEA8 ;
DR   Q02R98, TRUD_PSEAB ;  Q9HY04, TRUD_PSEAE ;  Q1I653, TRUD_PSEE4 ;
DR   Q4KHE9, TRUD_PSEF5 ;  C3K704, TRUD_PSEFS ;  Q3IDQ4, TRUD_PSEHT ;
DR   A4XWR3, TRUD_PSEMY ;  A5W822, TRUD_PSEP1 ;  Q3KH85, TRUD_PSEPF ;
DR   B0KSC6, TRUD_PSEPG ;  Q88MF2, TRUD_PSEPK ;  B1JB31, TRUD_PSEPW ;
DR   Q886L6, TRUD_PSESM ;  Q4ZWQ1, TRUD_PSEU2 ;  A4VJV1, TRUD_PSEU5 ;
DR   Q4FR14, TRUD_PSYA2 ;  Q9V107, TRUD_PYRAB ;  Q8ZTR2, TRUD_PYRAE ;
DR   A4WLG8, TRUD_PYRAR ;  Q8U0N1, TRUD_PYRFU ;  O59207, TRUD_PYRHO ;
DR   A1RRV7, TRUD_PYRIL ;  Q5JDB6, TRUD_PYRKO ;  B5F409, TRUD_SALA4 ;
DR   A9MF30, TRUD_SALAR ;  Q57KJ6, TRUD_SALCH ;  B5FTS3, TRUD_SALDC ;
DR   B5QW16, TRUD_SALEP ;  B5RDQ1, TRUD_SALG2 ;  B4TFW5, TRUD_SALHS ;
DR   B4T455, TRUD_SALNS ;  Q5PEG3, TRUD_SALPA ;  A9N2D1, TRUD_SALPB ;
DR   C0PXA5, TRUD_SALPC ;  B5BEY2, TRUD_SALPK ;  B4TTV9, TRUD_SALSV ;
DR   Q8Z473, TRUD_SALTI ;  Q8ZMF8, TRUD_SALTY ;  A8G9Z4, TRUD_SERP5 ;
DR   Q8EBR4, TRUD_SHEON ;  B2TZI6, TRUD_SHIB3 ;  Q31XA7, TRUD_SHIBS ;
DR   Q32CI5, TRUD_SHIDS ;  Q0T1H6, TRUD_SHIF8 ;  Q83QE3, TRUD_SHIFL ;
DR   Q3YYB7, TRUD_SHISS ;  Q30RS1, TRUD_SULDN ;  Q980V2, TRUD_SULSO ;
DR   Q976I1, TRUD_SULTO ;  Q9HLL3, TRUD_THEAC ;  C5A1W0, TRUD_THEGJ ;
DR   B1Y9W7, TRUD_THENV ;  B6YTE4, TRUD_THEON ;  C6A1K9, TRUD_THESM ;
DR   Q72IG5, TRUD_THET2 ;  Q5SI49, TRUD_THET8 ;  Q978K9, TRUD_THEVO ;
DR   Q31J61, TRUD_THICR ;  A5F9D8, TRUD_VIBC3 ;  Q9KUJ0, TRUD_VIBCH ;
DR   C3LS20, TRUD_VIBCM ;  Q5E330, TRUD_VIBF1 ;  B5FAF5, TRUD_VIBFM ;
DR   A7MTT9, TRUD_VIBHB ;  Q87LQ4, TRUD_VIBPA ;  Q8DC58, TRUD_VIBVU ;
DR   Q7MHQ6, TRUD_VIBVY ;  P59893, TRUD_WOLSU ;  Q8PLR6, TRUD_XANAC ;
DR   Q3BUS6, TRUD_XANC5 ;  Q4UTP6, TRUD_XANC8 ;  B0RU01, TRUD_XANCB ;
DR   Q8P9Y9, TRUD_XANCP ;  Q2P1L2, TRUD_XANOM ;  Q5GYK8, TRUD_XANOR ;
DR   A1JJT6, TRUD_YERE8 ;  A7FLX6, TRUD_YERP3 ;  Q1C476, TRUD_YERPA ;
DR   B2K579, TRUD_YERPB ;  Q8ZBP8, TRUD_YERPE ;  A9R117, TRUD_YERPG ;
DR   Q1CLR4, TRUD_YERPN ;  A4TPZ9, TRUD_YERPP ;  Q66EC1, TRUD_YERPS ;
DR   B1JJF6, TRUD_YERPY ;
//
ID   5.4.99.28
DE   tRNA pseudouridine(32) synthase.
AN   Pseudouridine synthase RluA.
CA   tRNA uridine(32) = tRNA pseudouridine(32).
CC   -!- The dual-specificity enzyme also catalyzes the formation of
CC       pseudouridine(746) in 23S rRNA.
CC   -!- cf. EC 5.4.99.29.
DR   Q8XA10, RLUA_ECO57 ;  Q8FL93, RLUA_ECOL6 ;  P0AA37, RLUA_ECOLI ;
DR   P59831, RLUA_HAEDU ;  P44782, RLUA_HAEIN ;  Q9CK02, RLUA_PASMU ;
DR   Q8Z9J5, RLUA_SALTI ;  Q8ZRV9, RLUA_SALTY ;  P0AA38, RLUA_SHIFL ;
DR   Q9KP71, RLUA_VIBCH ;  Q87LD3, RLUA_VIBPA ;  Q8DCG0, RLUA_VIBVU ;
DR   Q8ZIK1, RLUA_YERPE ;
//
ID   5.4.99.29
DE   23S rRNA pseudouridine(746) synthase.
AN   23S RNA Psi(746) synthase.
CA   23S rRNA uridine(746) = 23S rRNA pseudouridine(746).
CC   -!- RluA is the sole protein responsible for the in vivo formation of 23S
CC       RNA pseudouridine(746).
CC   -!- The dual-specificity enzyme also catalyzes the formation of
CC       uridine(32) in tRNA.
CC   -!- cf. EC 5.4.99.28.
DR   Q8XA10, RLUA_ECO57 ;  Q8FL93, RLUA_ECOL6 ;  P0AA37, RLUA_ECOLI ;
DR   P59831, RLUA_HAEDU ;  P44782, RLUA_HAEIN ;  Q9CK02, RLUA_PASMU ;
DR   Q8Z9J5, RLUA_SALTI ;  Q8ZRV9, RLUA_SALTY ;  P0AA38, RLUA_SHIFL ;
DR   Q9KP71, RLUA_VIBCH ;  Q87LD3, RLUA_VIBPA ;  Q8DCG0, RLUA_VIBVU ;
DR   Q8ZIK1, RLUA_YERPE ;
//
ID   5.4.99.30
DE   UDP-arabinopyranose mutase.
CA   UDP-beta-L-arabinofuranose = UDP-beta-L-arabinopyranose.
CC   -!- The reaction is reversible and at thermodynamic equilibrium the
CC       pyranose form is favored over the furanose form (90:10).
DR   Q9SRT9, RGP1_ARATH ;  Q8H8T0, RGP1_ORYSJ ;  Q9LFW1, RGP2_ARATH ;
DR   Q7FAY6, RGP2_ORYSJ ;  O22666, RGP3_ARATH ;  Q6Z4G3, RGP3_ORYSJ ;
DR   Q9LUE6, RGP4_ARATH ;  Q9FFD2, RGP5_ARATH ;
//
ID   5.4.99.31
DE   Thalianol synthase.
CA   (S)-squalene-2,3-epoxide = thalianol.
DR   Q9FI37, PEN4_ARATH ;
//
ID   5.4.99.32
DE   Protostadienol synthase.
CA   (S)-squalene-2,3-epoxide = (17Z)-protosta-17(20),24-dien-3-beta-ol.
CC   -!- (17Z)-protosta-17(20),24-dien-3-beta-ol is a precursor of the
CC       steroidal antibiotic helvolic acid.
//
ID   5.4.99.33
DE   Cucurbitadienol synthase.
CA   (S)-squalene-2,3-epoxide = cucurbitadienol.
//
ID   5.4.99.34
DE   Germanicol synthase.
CA   (S)-squalene-2,3-epoxide = germanicol.
CC   -!- The enzyme produces germanicol, beta-amyrin and lupeol in the ratio
CC       63:33:4.
//
ID   5.4.99.35
DE   Taraxerol synthase.
CA   (S)-squalene-2,3-epoxide = taraxerol.
CC   -!- The enzyme gives taraxerol, beta-amyrin and lupeol in the ratio
CC       70:17:13.
//
ID   5.4.99.36
DE   Isomultiflorenol synthase.
CA   (S)-squalene-2,3-epoxide = isomultiflorenol.
//
ID   5.5.1.1
DE   Muconate cycloisomerase.
AN   Cis,cis-muconate lactonizing enzyme I.
AN   Muconate cycloisomerase I.
AN   Muconate lactonizing enzyme.
CA   2,5-dihydro-5-oxofuran-2-acetate = cis,cis-hexadienedioate.
CF   Manganese.
CC   -!- Also acts, in the reverse reaction, on 3-methyl-cis,cis-hexa-
CC       dienedioate and, very slowly, on cis,trans-hexadienedioate.
CC   -!- Not identical with EC 5.5.1.7 or EC 5.5.1.11.
PR   PROSITE; PDOC00706;
DR   O33946, CATB1_ACILW;  O33949, CATB2_ACILW;  Q43931, CATB_ACIAD ;
DR   P08310, CATB_PSEPU ;  P95608, CATB_RHOOP ;  P46057, MLE_TRICU  ;
//
ID   5.5.1.2
DE   3-carboxy-cis,cis-muconate cycloisomerase.
AN   3-carboxymuconate lactonizing enzyme.
AN   Beta-carboxymuconate lactonizing enzyme.
AN   CMLE.
CA   2-carboxy-2,5-dihydro-5-oxofuran-2-acetate = cis,cis-butadiene-1,2,4-
CA   tricarboxylate.
PR   PROSITE; PDOC00147;
DR   Q59092, PCAB_ACIAD ;  O31385, PCAB_BRAJA ;  Q9I6Q8, PCAB_PSEAE ;
DR   P32427, PCAB_PSEPU ;
//
ID   5.5.1.3
DE   Tetrahydroxypteridine cycloisomerase.
CA   Tetrahydroxypteridine = xanthine-8-carboxylate.
//
ID   5.5.1.4
DE   Inositol-3-phosphate synthase.
AN   1L-myo-inositol-1-phosphate lyase (isomerizing).
AN   D-glucose 6-phosphate cycloaldolase.
AN   Glucocycloaldolase.
AN   Glucose 6-phosphate cyclase.
AN   Inositol 1-phosphate synthetase.
AN   Myo-inositol-1-phosphate synthase.
CA   D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate.
CF   NAD.
CC   -!- The NAD(+) dehydrogenates the -CHOH- group to -CO- at C-5 of the
CC       glucose 6-phosphate, making C-6 into an active methylene, able to
CC       condense with the -CHO at C-1; finally, the enzyme-bound NADH
CC       reconverts C-5 into the -CHOH- form.
DR   Q7ZXY0, INO1A_XENLA;  Q6DDT1, INO1B_XENLA;  P42801, INO1_ARATH ;
DR   Q2NL29, INO1_BOVIN ;  Q96348, INO1_BRANA ;  P42800, INO1_CANAL ;
DR   Q6FQI1, INO1_CANGA ;  P42802, INO1_CITPA ;  Q54N49, INO1_DICDI ;
DR   O97477, INO1_DROME ;  O65195, INO1_HORVU ;  Q9NPH2, INO1_HUMAN ;
DR   Q4R6E3, INO1_MACFA ;  Q9FPK7, INO1_MAIZE ;  Q40271, INO1_MESCR ;
DR   Q9JHU9, INO1_MOUSE ;  A0R7G6, INO1_MYCS2 ;  P71703, INO1_MYCTU ;
DR   Q9SSV4, INO1_NICPA ;  O64437, INO1_ORYSJ ;  Q41107, INO1_PHAVU ;
DR   Q6AYK3, INO1_RAT   ;  Q9FYV1, INO1_SESIN ;  P42803, INO1_SPIPO ;
DR   Q9LW96, INO1_TOBAC ;  Q9S7U0, INO1_WHEAT ;  P11986, INO1_YEAST ;
DR   Q38862, INO2_ARATH ;  Q9LX12, INO3_ARATH ;
//
ID   5.5.1.5
DE   Carboxy-cis,cis-muconate cyclase.
AN   3-carboxy-cis,cis-muconate lactonizing enzyme.
AN   3-carboxymuconate cyclase.
CA   3-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 3-carboxy-cis,cis-muconate.
DR   P38677, CMLE_NEUCR ;
//
ID   5.5.1.6
DE   Chalcone isomerase.
AN   Chalcone--flavonone isomerase.
CA   A chalcone = a flavanone.
DR   Q53B75, CF1B1_SOYBN;  Q53B70, CF1B2_SOYBN;  Q93XE6, CFI1A_SOYBN;
DR   P41088, CFI1_ARATH ;  A1E260, CFI1_CHRMO ;  Q4AE11, CFI1_FRAAN ;
DR   Q8H0G2, CFI1_LOTJA ;  P28012, CFI1_MEDSA ;  P11650, CFI1_PETHY ;
DR   O81980, CFI1_SOYBN ;  P51117, CFI1_VITVI ;  Q53B74, CFI2A_SOYBN;
DR   A7ISP5, CFI2B_SOYBN;  Q9FKW3, CFI2_ARATH ;  A1E261, CFI2_CHRMO ;
DR   Q4AE12, CFI2_FRAAN ;  Q8H0G1, CFI2_LOTJA ;  P28013, CFI2_MEDSA ;
DR   P11651, CFI2_PETHY ;  A5ANT9, CFI2_VITVI ;  Q8H0F6, CFI3_LOTJA ;
DR   Q9M5B3, CFI3_PETHY ;  A7ISP6, CFI3_SOYBN ;  Q6QHK0, CFI_ALLCE  ;
DR   Q9LKC3, CFI_ARALP  ;  Q42663, CFI_CALCH  ;  Q45QI7, CFI_CAMSI  ;
DR   Q3Y4F4, CFI_CANGE  ;  Q9ZWR1, CFI_CITSI  ;  A4F1Q8, CFI_CLITE  ;
DR   Q43754, CFI_DIACA  ;  O65333, CFI_ELAUM  ;  Q6BEH3, CFI_EUSGR  ;
DR   Q565D8, CFI_GENTR  ;  A2IBF8, CFI_GOSHI  ;  Q8S3X0, CFI_HORVU  ;
DR   Q8S911, CFI_IPOBA  ;  O22604, CFI_IPOPU  ;  Q08704, CFI_MAIZE  ;
DR   A2XNF0, CFI_ORYSI  ;  Q84T92, CFI_ORYSJ  ;  P41089, CFI_PEA    ;
DR   P14298, CFI_PHAVU  ;  Q43056, CFI_PUEML  ;  A5HBK6, CFI_PYRCO  ;
DR   O22651, CFI_RAPSA  ;  Q8LKP9, CFI_SAUME  ;  Q33DL3, CFI_TOBAC  ;
DR   Q2PF16, CFI_VERHY  ;
//
ID   5.5.1.7
DE   Chloromuconate cycloisomerase.
AN   Muconate cycloisomerase II.
CA   2-chloro-2,5-dihydro-5-oxofuran-2-acetate = 3-chloro-cis,cis-muconate.
CF   Manganese.
CC   -!- Spontaneous elimination of HCl produces cis-4-carboxymethylenebut-2-
CC       en-4-olide.
CC   -!- Also acts in reverse direction on 2-chloro-cis,cis-muconate.
CC   -!- Not identical with EC 5.5.1.1 or EC 5.5.1.11.
PR   PROSITE; PDOC00706;
DR   P83763, CBNB_CUPNE ;  P11452, CLCB_PSEPU ;  P27099, TCBD_PSESQ ;
DR   P05404, TFDD1_CUPPJ;  P42428, TFDD2_CUPPJ;  Q9RNZ9, TFDD_DELAC ;
//
ID   5.5.1.8
DE   Bornyl diphosphate synthase.
AN   Bornyl pyrophosphate synthase.
AN   Bornyl pyrophosphate synthetase.
AN   Geranyl-diphosphate cyclase.
CA   Geranyl diphosphate = (+)-bornyl diphosphate.
DR   O81192, BPPS_SALOF ;
//
ID   5.5.1.9
DE   Cycloeucalenol cycloisomerase.
AN   Cycloeucalenol--obtusifoliol isomerase.
CA   Cycloeucalenol = obtusifoliol.
CC   -!- Opens the cyclopropane ring of a number of related 4-alpha-methyl-9-
CC       beta-19-cyclosterols, but not those with a 4-beta-methyl group, with
CC       formation of an 8(9) double bond.
CC   -!- Involved in the synthesis of plant sterols.
DR   Q9M643, CCI1_ARATH ;
//
ID   5.5.1.10
DE   Alpha-pinene-oxide decyclase.
AN   Alpha-pinene oxide lyase.
CA   Alpha-pinene oxide = (Z)-2-methyl-5-isopropylhexa-2,5-dienal.
CC   -!- Both rings of pinene are cleaved in the reaction.
//
ID   5.5.1.11
DE   Dichloromuconate cycloisomerase.
CA   2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate = 2,4-dichloro-cis,cis-
CA   muconate.
CF   Manganese.
CC   -!- The product of cyclisomerization of dichloro-cis,cis-muconate
CC       spontaneously eliminates chloride to produce cis-4-carboxymethylene-
CC       3-chlorobut-2-en-4-olide.
CC   -!- Also acts, in the reverse direction, on cis,cis-muconate and its
CC       monochloro-derivatives, but with lower affinity.
CC   -!- Not identical with EC 5.5.1.1 or EC 5.5.1.7.
//
ID   5.5.1.12
DE   Copalyl diphosphate synthase.
CA   Geranylgeranyl diphosphate = (+)-copalyl diphosphate.
CC   -!- Part of a bifunctional enzyme involved in the biosynthesis of
CC       abietadiene.
CC   -!- See also EC 4.2.3.18.
DR   Q947C4, TPSD1_GINBI;  Q675L4, TPSD1_PICAB;  Q50EK2, TPSD1_PINTA;
DR   Q675L5, TPSD2_PICAB;  Q38710, TPSDV_ABIGR;
//
ID   5.5.1.13
DE   Ent-copalyl diphosphate synthase.
AN   Ent-CDP synthase.
AN   Ent-kaurene synthase A.
AN   Ent-kaurene synthetase A.
CA   Geranylgeranyl diphosphate = ent-copalyl diphosphate.
CC   -!- Part of a bifunctional enzyme involved in the biosynthesis of
CC       kaurene.
CC   -!- See also EC 4.2.3.19.
DR   Q6ET36, CPS1_ORYSJ ;  Q5MQ85, CPS2_ORYSI ;  Q6Z5I0, CPS2_ORYSJ ;
DR   Q9UVY5, CPSKS_GIBFU;  O13284, CPSKS_PHASA;  Q38802, KSA_ARATH  ;
DR   O04408, KSA_PEA    ;
//
ID   5.5.1.14
DE   Syn-copalyl-diphosphate synthase.
AN   Syn-copalyl diphosphate synthase.
AN   Syn-CPP synthase.
CA   Geranylgeranyl diphosphate = 9-alpha-copalyl diphosphate.
CF   Magnesium.
CC   -!- This class II terpene synthase produces syn-copalyl diphosphate,
CC       a precursor of several rice phytoalexins, including oryzalexin S and
CC       momilactones A and B.
CC   -!- Phytoalexins are diterpenoid secondary metabolites that are involved
CC       in the defense mechanism of the plant, and are produced in response
CC       to pathogen attack through the perception of elicitor signal
CC       molecules such as chitin oligosaccharide, or after exposure to UV
CC       irradiation.
CC   -!- Constitutively expressed in the roots of plants where one of its
CC       products, momilactone B, acts as an allelochemical (a molecule
CC       released into the environment to suppress the growth of neighboring
CC       plants).
CC   -!- In other tissues the enzyme is up-regulated by conditions that
CC       stimulate the biosynthesis of phytoalexins.
DR   Q6E7D7, CPS4_ORYSI ;  Q0JF02, CPS4_ORYSJ ;
//
ID   5.5.1.15
DE   Terpentedienyl-diphosphate synthase.
AN   Clerodadienyl diphosphate synthase.
AN   Terpentedienol diphosphate synthase.
CA   Geranylgeranyl diphosphate = terpentedienyl diphosphate.
CF   Magnesium.
CC   -!- Contains a DXDD motif, which is a characteristic of diterpene cylases
CC       whose reactions are initiated by protonation at the 14,15-double bond
CC       of geranylgeranyl diphosphate (GGDP).
CC   -!- The triggering proton is lost at the end of the cyclization reaction.
CC   -!- The product of the reaction, terpentedienyl diphosphate, is the
CC       substrate for EC 4.2.3.36 and is a precursor of the diterpenoid
CC       antibiotic terpentecin.
//
ID   5.5.1.16
DE   Halimadienyl-diphosphate synthase.
AN   Tuberculosinol diphosphate synthase.
CA   Geranylgeranyl diphosphate = halima-5(6),13-dien-15-yl diphosphate.
CF   Magnesium.
CC   -!- Found in pathogenic prokaryotes such as Mycobacterium tuberculosis
CC       but not in non-pathogens such as Mycobacterium smegmatis so may play
CC       a role in pathogenicity.
CC   -!- The product of the reaction is subsequently dephosphorylated yielding
CC       tuberculosinol (halima-5(6),13-dien-15-ol).
//
ID   5.5.1.17
DE   (S)-beta-macrocarpene synthase.
CA   (S)-beta-bisabolene = (S)-beta-macrocarpene.
DR   Q1EG72, TPS11_MAIZE;  Q5GJ60, TPS6_MAIZE ;
//
ID   5.5.1.n1
DE   D-ribose pyranase.
CA   Beta-D-ribopyranose = beta-D-ribofuranose.
CC   -!- The enzyme also catalyzes the conversion between beta-allofuranose
CC       and beta-allopyranose.
DR   Q1AXG1, RBSD1_RUBXD;  B1VNF2, RBSD1_STRGG;  Q1AUT6, RBSD2_RUBXD;
DR   B1VU78, RBSD2_STRGG;  A1TUV3, RBSD_ACIAC ;  A3N2W7, RBSD_ACTP2 ;
DR   B3H2R4, RBSD_ACTP7 ;  B0BS95, RBSD_ACTPJ ;  A6VKS7, RBSD_ACTSZ ;
DR   A0KKN1, RBSD_AERHH ;  A4SMC0, RBSD_AERS4 ;  B6EKH2, RBSD_ALISL ;
DR   A7Z9G4, RBSD_BACA2 ;  C3P0E9, RBSD_BACAA ;  C3LG97, RBSD_BACAC ;
DR   A0R9V2, RBSD_BACAH ;  Q81V37, RBSD_BACAN ;  B7JQF1, RBSD_BACC0 ;
DR   Q73DH8, RBSD_BACC1 ;  B7IXT0, RBSD_BACC2 ;  C1EXK2, RBSD_BACC3 ;
DR   B7HBU7, RBSD_BACC4 ;  B7HW89, RBSD_BACC7 ;  A7GLA2, RBSD_BACCN ;
DR   B9J4V7, RBSD_BACCQ ;  Q81HW9, RBSD_BACCR ;  Q63FY0, RBSD_BACCZ ;
DR   Q9K6K0, RBSD_BACHD ;  Q6HNE8, RBSD_BACHK ;  Q65E56, RBSD_BACLD ;
DR   A8FI51, RBSD_BACP2 ;  Q5WC30, RBSD_BACSK ;  P36946, RBSD_BACSU ;
DR   A9VEU6, RBSD_BACWK ;  B8G635, RBSD_CHLAD ;  Q7NTN5, RBSD_CHRVO ;
DR   A8ACQ4, RBSD_CITK8 ;  B2UZT8, RBSD_CLOBA ;  B2TK87, RBSD_CLOBB ;
DR   A0Q217, RBSD_CLONN ;  Q0TPX4, RBSD_CLOP1 ;  Q8XJX2, RBSD_CLOPE ;
DR   Q0SSI9, RBSD_CLOPS ;  Q891M0, RBSD_CLOTE ;  B5Y646, RBSD_COPPD ;
DR   A4QDL6, RBSD_CORGB ;  Q8NR09, RBSD_CORGL ;  C6BY79, RBSD_DESAD ;
DR   A4J7I2, RBSD_DESRM ;  A7ZTV9, RBSD_ECO24 ;  B7UML3, RBSD_ECO27 ;
DR   B7MGG8, RBSD_ECO45 ;  B7L894, RBSD_ECO55 ;  Q8XAW8, RBSD_ECO57 ;
DR   B5YY06, RBSD_ECO5E ;  B7NR51, RBSD_ECO7I ;  B7N2I7, RBSD_ECO81 ;
DR   B7M5A4, RBSD_ECO8A ;  C4ZZ26, RBSD_ECOBW ;  B1X9X5, RBSD_ECODH ;
DR   A8A6L1, RBSD_ECOHS ;  A1AHS8, RBSD_ECOK1 ;  Q0TAW1, RBSD_ECOL5 ;
DR   Q8FBS4, RBSD_ECOL6 ;  B1IWZ0, RBSD_ECOLC ;  P04982, RBSD_ECOLI ;
DR   B7NF64, RBSD_ECOLU ;  B6I3Y5, RBSD_ECOSE ;  B1LL75, RBSD_ECOSM ;
DR   Q1R4I4, RBSD_ECOUT ;  C5BDG5, RBSD_EDWI9 ;  A4WGD9, RBSD_ENT38 ;
DR   Q82ZT7, RBSD_ENTFA ;  A7MMV4, RBSD_ENTS8 ;  Q6DB88, RBSD_ERWCT ;
DR   B7LK93, RBSD_ESCF3 ;  B1YL34, RBSD_EXIS2 ;  C4KZD1, RBSD_EXISA ;
DR   Q5KUX2, RBSD_GEOKA ;  A4IT64, RBSD_GEOTN ;  Q4QN45, RBSD_HAEI8 ;
DR   A5U9Z0, RBSD_HAEIE ;  A5UH08, RBSD_HAEIG ;  P44734, RBSD_HAEIN ;
DR   B8F777, RBSD_HAEPS ;  Q0I1S1, RBSD_HAES1 ;  B0UV47, RBSD_HAES2 ;
DR   B0TIM6, RBSD_HELMI ;  B5XZK8, RBSD_KLEP3 ;  A6TG52, RBSD_KLEP7 ;
DR   C5CEY9, RBSD_KOSOT ;  Q5FJ20, RBSD_LACAC ;  Q03Q56, RBSD_LACBA ;
DR   Q03CA5, RBSD_LACC3 ;  B3W789, RBSD_LACCB ;  B2GEJ1, RBSD_LACF3 ;
DR   Q043F6, RBSD_LACGA ;  Q74J96, RBSD_LACJO ;  Q9CF43, RBSD_LACLA ;
DR   A2RJD5, RBSD_LACLM ;  Q02XM8, RBSD_LACLS ;  Q88RZ2, RBSD_LACPL ;
DR   A5VIK0, RBSD_LACRD ;  B2G634, RBSD_LACRJ ;  Q38Z79, RBSD_LACSS ;
DR   C1D8A6, RBSD_LARHH ;  B2A2D7, RBSD_NATTJ ;  Q8ENB2, RBSD_OCEIH ;
DR   Q04DK7, RBSD_OENOB ;  Q9CP97, RBSD_PASMU ;  C6DJF3, RBSD_PECCP ;
DR   Q03DK3, RBSD_PEDPA ;  A9BJQ0, RBSD_PETMO ;  Q7NA80, RBSD_PHOLL ;
DR   Q6LH12, RBSD_PHOPR ;  Q6ABP6, RBSD_PROAC ;  B4EU30, RBSD_PROMH ;
DR   Q48JS8, RBSD_PSE14 ;  Q1IC21, RBSD_PSEE4 ;  Q4KEW9, RBSD_PSEF5 ;
DR   C3JZP4, RBSD_PSEFS ;  A5W5E7, RBSD_PSEP1 ;  Q3KEY9, RBSD_PSEPF ;
DR   B0KKS4, RBSD_PSEPG ;  Q88K33, RBSD_PSEPK ;  B1J6T8, RBSD_PSEPW ;
DR   Q883I5, RBSD_PSESM ;  Q4ZUH3, RBSD_PSEU2 ;  A1SRU1, RBSD_PSYIN ;
DR   Q7UU60, RBSD_RHOBA ;  B5EZ14, RBSD_SALA4 ;  A9MJQ1, RBSD_SALAR ;
DR   Q57HW2, RBSD_SALCH ;  B5FN51, RBSD_SALDC ;  B5QVE8, RBSD_SALEP ;
DR   B5RFU7, RBSD_SALG2 ;  B4TAZ0, RBSD_SALHS ;  B4SYE9, RBSD_SALNS ;
DR   Q5PJX6, RBSD_SALPA ;  A9MXC5, RBSD_SALPB ;  C0Q2P8, RBSD_SALPC ;
DR   B5BIQ2, RBSD_SALPK ;  B4TN49, RBSD_SALSV ;  Q8Z2R3, RBSD_SALTI ;
DR   Q8ZKW0, RBSD_SALTY ;  A8GLK3, RBSD_SERP5 ;  B0TS18, RBSD_SHEHH ;
DR   A8GZV5, RBSD_SHEPA ;  B2TU31, RBSD_SHIB3 ;  Q31UM5, RBSD_SHIBS ;
DR   Q0SYV0, RBSD_SHIF8 ;  Q83PJ1, RBSD_SHIFL ;  Q3YVK9, RBSD_SHISS ;
DR   A7WXT5, RBSD_STAA1 ;  A6TY54, RBSD_STAA2 ;  Q2FK01, RBSD_STAA3 ;
DR   Q2G1A5, RBSD_STAA8 ;  A5IPD8, RBSD_STAA9 ;  Q2YVA4, RBSD_STAAB ;
DR   Q5HJA7, RBSD_STAAC ;  A6QDP3, RBSD_STAAE ;  Q99WV6, RBSD_STAAM ;
DR   Q7A7T6, RBSD_STAAN ;  Q6GK42, RBSD_STAAR ;  Q6GCK3, RBSD_STAAS ;
DR   A8Z0N3, RBSD_STAAT ;  Q7A1V6, RBSD_STAAW ;  B9DIF1, RBSD_STACT ;
DR   Q5HL86, RBSD_STAEQ ;  Q8CN17, RBSD_STAES ;  Q4LA40, RBSD_STAHJ ;
DR   Q49XF7, RBSD_STAS1 ;  Q3K3R1, RBSD_STRA1 ;  Q8E7N8, RBSD_STRA3 ;
DR   Q8E280, RBSD_STRA5 ;  Q82CM8, RBSD_STRAW ;  Q9RDH8, RBSD_STRCO ;
DR   B9DUX3, RBSD_STRU0 ;  Q67RD6, RBSD_SYMTH ;  B7IGD0, RBSD_THEAB ;
DR   A8F3M5, RBSD_THELT ;  Q9X054, RBSD_THEMA ;  B9KA10, RBSD_THENN ;
DR   A5INL8, RBSD_THEP1 ;  B0KDE7, RBSD_THEP3 ;  B0K1M3, RBSD_THEPX ;
DR   Q8RD44, RBSD_THETN ;  C5CL95, RBSD_VARPS ;  A5F1C1, RBSD_VIBC3 ;
DR   Q9KN38, RBSD_VIBCH ;  Q5E4V7, RBSD_VIBF1 ;  B5FEJ4, RBSD_VIBFM ;
DR   A7N2S3, RBSD_VIBHB ;  Q87H78, RBSD_VIBPA ;  Q8D7T8, RBSD_VIBVU ;
DR   Q7MEV2, RBSD_VIBVY ;  A1JHR8, RBSD_YERE8 ;  A7FCN3, RBSD_YERP3 ;
DR   Q1CC43, RBSD_YERPA ;  B2K7I5, RBSD_YERPB ;  Q7CLE5, RBSD_YERPE ;
DR   A9QYG7, RBSD_YERPG ;  Q1CNU0, RBSD_YERPN ;  A4TSH7, RBSD_YERPP ;
DR   Q66GH4, RBSD_YERPS ;  B1JR25, RBSD_YERPY ;
//
ID   5.99.1.1
DE   Thiocyanate isomerase.
AN   Isothiocyanate isomerase.
CA   Benzyl isothiocyanate = benzyl thiocyanate.
//
ID   5.99.1.2
DE   DNA topoisomerase.
AN   DNA topoisomerase I.
AN   Nicking-closing enzyme.
AN   Omega-protein.
AN   Relaxing enzyme.
AN   Swivelase.
AN   Type I DNA topoisomerase.
AN   Untwisting enzyme.
CA   ATP-independent breakage of single-stranded DNA, followed by passage and
CA   rejoining.
CC   -!- Brings about the conversion of one topological isomer of DNA into
CC       another, e.g. the relaxation of superhelical turns in DNA,
CC       the interconversion of simple and knotted rings of single-stranded
CC       DNA, and the intertwisting of single-stranded rings of complementary
CC       sequences (cf. EC 5.99.1.3).
PR   PROSITE; PDOC00159;
PR   PROSITE; PDOC00333;
DR   P13658, MBEA_ECOLX ;  P07112, MOBA2_ECOLX;  Q7T6X9, TOP1E_MIMIV;
DR   Q969P6, TOP1M_HUMAN;  Q8R4U6, TOP1M_MOUSE;  A9Q1D5, TOP1M_PANTR;
DR   Q6IM78, TOP1M_RAT  ;  Q5UQB5, TOP1P_MIMIV;  Q9PHK2, TOP1P_XYLFA;
DR   Q9YB01, TOP1_AERPE ;  O66893, TOP1_AQUAE ;  P30181, TOP1_ARATH ;
DR   O28469, TOP1_ARCFU ;  P40114, TOP1_BACAN ;  Q9KA23, TOP1_BACHD ;
DR   P34184, TOP1_BACPE ;  P39814, TOP1_BACSU ;  O51768, TOP1_BORBU ;
DR   P57371, TOP1_BUCAI ;  Q8K9P7, TOP1_BUCAP ;  O17966, TOP1_CAEEL ;
DR   Q9PLZ2, TOP1_CAMJE ;  Q00313, TOP1_CANAL ;  Q7YR26, TOP1_CHLAE ;
DR   Q07050, TOP1_CRIGR ;  P93119, TOP1_DAUCA ;  Q54RC3, TOP1_DICDI ;
DR   P30189, TOP1_DROME ;  P06612, TOP1_ECOLI ;  P46155, TOP1_ENTAE ;
DR   O34204, TOP1_FERIS ;  P43012, TOP1_HAEIN ;  Q9ZMV7, TOP1_HELPJ ;
DR   P55991, TOP1_HELPY ;  P11387, TOP1_HUMAN ;  Q9CG80, TOP1_LACLA ;
DR   Q59046, TOP1_METJA ;  O27661, TOP1_METTH ;  Q04750, TOP1_MOUSE ;
DR   P0A621, TOP1_MYCBO ;  Q9JN65, TOP1_MYCGA ;  P47368, TOP1_MYCGE ;
DR   O69548, TOP1_MYCLE ;  P78032, TOP1_MYCPN ;  P0A620, TOP1_MYCTU ;
DR   Q9CN30, TOP1_PASMU ;  Q9HZJ5, TOP1_PSEAE ;  Q9UYS8, TOP1_PYRAB ;
DR   O73954, TOP1_PYRFU ;  O58356, TOP1_PYRHO ;  Q9WUL0, TOP1_RAT   ;
DR   P16472, TOP1_RFVKA ;  Q1RIM1, TOP1_RICBR ;  Q92IH1, TOP1_RICCN ;
DR   Q4UM42, TOP1_RICFE ;  Q9ZDK2, TOP1_RICPR ;  Q68X45, TOP1_RICTY ;
DR   P0A2I2, TOP1_SALTI ;  P0A2I1, TOP1_SALTY ;  P07799, TOP1_SCHPO ;
DR   Q2FHI8, TOP1_STAA3 ;  Q2FZ32, TOP1_STAA8 ;  Q2YXL8, TOP1_STAAB ;
DR   Q5HGI2, TOP1_STAAC ;  Q99UM1, TOP1_STAAM ;  Q7A5Y5, TOP1_STAAN ;
DR   Q6GHI5, TOP1_STAAR ;  Q6G9W3, TOP1_STAAS ;  Q06AK7, TOP1_STAAU ;
DR   Q8NWZ9, TOP1_STAAW ;  Q5HPU2, TOP1_STAEQ ;  Q8CSU3, TOP1_STAES ;
DR   Q4L5V2, TOP1_STAHJ ;  Q49X35, TOP1_STAS1 ;  Q9X909, TOP1_STRCO ;
DR   P34185, TOP1_SYNE7 ;  P73810, TOP1_SYNY3 ;  Q9HM08, TOP1_THEAC ;
DR   P46799, TOP1_THEMA ;  O83409, TOP1_TREPA ;  P41511, TOP1_USTMA ;
DR   Q76ZS7, TOP1_VACCA ;  P68697, TOP1_VACCC ;  P68698, TOP1_VACCW ;
DR   P32989, TOP1_VAR67 ;  Q9KRB2, TOP1_VIBCH ;  P41512, TOP1_XENLA ;
DR   Q9PEV8, TOP1_XYLFA ;  Q87AQ6, TOP1_XYLFT ;  P04786, TOP1_YEAST ;
DR   Q9X3X7, TOP1_ZYMMO ;  Q9NG98, TOP3A_DROME;  Q13472, TOP3A_HUMAN;
DR   O70157, TOP3A_MOUSE;  O96651, TOP3B_DROME;  O95985, TOP3B_HUMAN;
DR   Q9Z321, TOP3B_MOUSE;  A0R979, TOP3_BACAH ;  Q81Z97, TOP3_BACAN ;
DR   Q73E74, TOP3_BACC1 ;  Q81IH1, TOP3_BACCR ;  Q63GK5, TOP3_BACCZ ;
DR   Q6HP19, TOP3_BACHK ;  Q65N90, TOP3_BACLD ;  Q5WAX6, TOP3_BACSK ;
DR   P96583, TOP3_BACSU ;  O61660, TOP3_CAEEL ;  Q8T2T7, TOP3_DICDI ;
DR   P14294, TOP3_ECOLI ;  P43704, TOP3_HAEIN ;  Q9CP53, TOP3_PASMU ;
DR   Q8Z6F5, TOP3_SALTI ;  P40687, TOP3_SALTY ;  O60126, TOP3_SCHPO ;
DR   Q2FEN5, TOP3_STAA3 ;  Q2FW03, TOP3_STAA8 ;  P0C2W6, TOP3_STAAB ;
DR   Q5HDV4, TOP3_STAAC ;  Q99S17, TOP3_STAAM ;  Q7A455, TOP3_STAAN ;
DR   Q6GEH9, TOP3_STAAR ;  Q6G767, TOP3_STAAS ;  Q7A075, TOP3_STAAW ;
DR   Q5HLZ4, TOP3_STAEQ ;  Q8CRF7, TOP3_STAES ;  Q4L8B8, TOP3_STAHJ ;
DR   Q49ZH2, TOP3_STAS1 ;  Q9KQF5, TOP3_VIBCH ;  P13099, TOP3_YEAST ;
//
ID   5.99.1.3
DE   DNA topoisomerase (ATP-hydrolyzing).
AN   DNA gyrase.
AN   DNA topoisomerase II.
AN   Type II DNA topoisomerase.
CA   ATP-dependent breakage, passage and rejoining of double-stranded DNA.
CC   -!- Can introduce negative superhelical turns into double-stranded
CC       circular DNA.
CC   -!- One unit has nicking-closing activity, and another catalyzes super-
CC       twisting and hydrolysis of ATP (cf. EC 5.99.1.2).
PR   PROSITE; PDOC00160;
DR   P48369, GYRA_AERSA ;  D5ECW5, GYRA_AMICL ;  O67108, GYRA_AQUAE ;
DR   Q9CAF6, GYRA_ARATH ;  O50628, GYRA_BACHD ;  P05653, GYRA_BACSU ;
DR   O51396, GYRA_BORBU ;  B2S0D7, GYRA_BORHD ;  C0R046, GYRA_BRAHW ;
DR   P57277, GYRA_BUCAI ;  Q8K9W2, GYRA_BUCAP ;  Q89AS3, GYRA_BUCBP ;
DR   P47235, GYRA_CAMFE ;  Q03470, GYRA_CAMJE ;  Q9PKK4, GYRA_CHLMU ;
DR   Q9Z8R4, GYRA_CHLPN ;  O84192, GYRA_CHLTR ;  P94605, GYRA_CLOAB ;
DR   D8K235, GYRA_DEHLB ;  C1CVF4, GYRA_DEIDV ;  P0AES4, GYRA_ECOLI ;
DR   P41513, GYRA_ERWCA ;  P35810, GYRA_FIBSS ;  Q0BST5, GYRA_GRABC ;
DR   P43700, GYRA_HAEIN ;  P21557, GYRA_HALL2 ;  Q18GY3, GYRA_HALWD ;
DR   Q9ZLD9, GYRA_HELPJ ;  P48370, GYRA_HELPY ;  P14829, GYRA_KLEOX ;
DR   C5CHA8, GYRA_KOSOT ;  Q1MQ89, GYRA_LAWIP ;  B0S912, GYRA_LEPBA ;
DR   B3PN30, GYRA_MYCA5 ;  Q49166, GYRA_MYCFV ;  P47719, GYRA_MYCGA ;
DR   P47250, GYRA_MYCGE ;  Q49467, GYRA_MYCGO ;  Q49608, GYRA_MYCKA ;
DR   Q57532, GYRA_MYCLE ;  O33149, GYRA_MYCMA ;  P22446, GYRA_MYCPN ;
DR   P48354, GYRA_MYCS2 ;  Q07702, GYRA_MYCTU ;  P72065, GYRA_MYCXE ;
DR   P48371, GYRA_NEIGO ;  Q5YLB5, GYRA_NICBE ;  A1SCM2, GYRA_NOCSJ ;
DR   Q7XZF7, GYRA_ORYSJ ;  P48372, GYRA_PSEAE ;  Q1RID9, GYRA_RICBR ;
DR   Q92IZ6, GYRA_RICCN ;  Q4UKM1, GYRA_RICFE ;  P41080, GYRA_RICPR ;
DR   Q68XG2, GYRA_RICTY ;  P37411, GYRA_SALTY ;  P0AES5, GYRA_SHIFL ;
DR   P34030, GYRA_SPICI ;  Q2FKQ0, GYRA_STAA3 ;  Q2G2Q0, GYRA_STAA8 ;
DR   Q5HJZ0, GYRA_STAAC ;  Q932M0, GYRA_STAAM ;  Q99XG5, GYRA_STAAN ;
DR   Q6GKT9, GYRA_STAAR ;  Q6GD84, GYRA_STAAS ;  P20831, GYRA_STAAU ;
DR   Q8NKW8, GYRA_STAAW ;  P0C0Q9, GYRA_STAEP ;  Q5HK04, GYRA_STAEQ ;
DR   P0C0R0, GYRA_STAES ;  P35885, GYRA_STRCO ;  Q9L7Q5, GYRA_STRP1 ;
DR   P0DG02, GYRA_STRP3 ;  Q5XC58, GYRA_STRP6 ;  Q8P116, GYRA_STRP8 ;
DR   P72524, GYRA_STRPN ;  P0DG03, GYRA_STRPQ ;  Q8DPM2, GYRA_STRR6 ;
DR   P50071, GYRA_STRSH ;  Q55738, GYRA_SYNY3 ;  O33926, GYRA_THEMA ;
DR   O83051, GYRA_TREPA ;  Q9PR63, GYRA_UREPA ;  Q94BZ7, GYRBM_ARATH;
DR   Q9SS38, GYRBP_ARATH;  P50074, GYRBR_STRSH;  P50075, GYRBS_STRSH;
DR   Q43907, GYRB_ACIBA ;  Q43947, GYRB_ACICA ;  Q44270, GYRB_ACIG3 ;
DR   Q44271, GYRB_ACIG6 ;  Q44272, GYRB_ACIG9 ;  Q44273, GYRB_ACIGA ;
DR   Q44274, GYRB_ACIGB ;  Q44065, GYRB_ACIHA ;  Q44081, GYRB_ACIJO ;
DR   Q44080, GYRB_ACIJU ;  Q44088, GYRB_ACILW ;  Q44277, GYRB_ACIS6 ;
DR   Q44278, GYRB_ACIS7 ;  Q44275, GYRB_ACIS8 ;  Q44276, GYRB_ACIS9 ;
DR   O67137, GYRB_AQUAE ;  O29720, GYRB_ARCFU ;  Q9X3Y6, GYRB_BACAN ;
DR   Q9X3Y3, GYRB_BACCE ;  O50627, GYRB_BACHD ;  Q9X3Y5, GYRB_BACMY ;
DR   P05652, GYRB_BACSU ;  P94281, GYRB_BARBK ;  P33769, GYRB_BORBU ;
DR   Q9ZFK1, GYRB_BORHE ;  P57126, GYRB_BUCAI ;  P29435, GYRB_BUCAP ;
DR   Q89B37, GYRB_BUCBP ;  O87667, GYRB_CAMJE ;  B8GXQ0, GYRB_CAUCN ;
DR   P0CAX1, GYRB_CAUCR ;  Q9FAX2, GYRB_CHIJA ;  Q9PKK3, GYRB_CHLMU ;
DR   Q9Z8R3, GYRB_CHLPN ;  O84193, GYRB_CHLTR ;  P94604, GYRB_CLOAB ;
DR   Q9LCK0, GYRB_CYTAU ;  Q9LCK1, GYRB_CYTHU ;  P0AES7, GYRB_ECO57 ;
DR   P0AES6, GYRB_ECOLI ;  Q9FAX1, GYRB_FLEEL ;  P43701, GYRB_HAEIN ;
DR   P21558, GYRB_HALL2 ;  D4GZ01, GYRB_HALVD ;  Q9ZLX3, GYRB_HELPJ ;
DR   P55992, GYRB_HELPY ;  Q9ZAQ6, GYRB_MYCAT ;  P50028, GYRB_MYCCT ;
DR   P47720, GYRB_MYCGA ;  P47249, GYRB_MYCGE ;  P43053, GYRB_MYCHP ;
DR   Q59533, GYRB_MYCLE ;  Q9L7L3, GYRB_MYCPA ;  P22447, GYRB_MYCPN ;
DR   A0QNE0, GYRB_MYCS2 ;  P0C559, GYRB_MYCSM ;  A5TY73, GYRB_MYCTA ;
DR   P0C5C5, GYRB_MYCTU ;  O33367, GYRB_MYXXA ;  P22118, GYRB_NEIGO ;
DR   Q5YLB4, GYRB_NICBE ;  Q5NBJ3, GYRB_ORYSJ ;  P22840, GYRB_PROMI ;
DR   Q9I7C2, GYRB_PSEAE ;  P13364, GYRB_PSEPU ;  P31860, GYRB_RHOCA ;
DR   Q1RHT8, GYRB_RICBR ;  Q92H87, GYRB_RICCN ;  Q4UKX5, GYRB_RICFE ;
DR   Q9ZCX2, GYRB_RICPR ;  Q68WF6, GYRB_RICTY ;  P0A2I4, GYRB_SALTI ;
DR   P0A2I3, GYRB_SALTY ;  P0AES8, GYRB_SHIFL ;  P34031, GYRB_SPICI ;
DR   Q2FKQ1, GYRB_STAA3 ;  Q5HJZ1, GYRB_STAAC ;  P66936, GYRB_STAAM ;
DR   P66937, GYRB_STAAN ;  Q6GKU0, GYRB_STAAR ;  Q6GD85, GYRB_STAAS ;
DR   P0A0K8, GYRB_STAAU ;  P0A0K7, GYRB_STAAW ;  Q5HK03, GYRB_STAEQ ;
DR   Q8CQK4, GYRB_STAES ;  P35886, GYRB_STRCO ;  Q9A0L0, GYRB_STRP1 ;
DR   P0DG04, GYRB_STRP3 ;  Q5XD05, GYRB_STRP6 ;  Q8P1M4, GYRB_STRP8 ;
DR   P0A4L9, GYRB_STRPN ;  P0DG05, GYRB_STRPQ ;  P0A4M0, GYRB_STRR6 ;
DR   P77966, GYRB_SYNY3 ;  P77993, GYRB_THEMA ;  O87545, GYRB_TREDE ;
DR   O08399, GYRB_TREPA ;  Q9KVX3, GYRB_VIBCH ;  O51859, GYRB_VIBPA ;
DR   Q9YCB6, RGYR1_AERPE;  O67037, RGYR1_AQUAE;  Q97ZZ8, RGYR1_SULSO;
DR   Q971T7, RGYR1_SULTO;  Q9YC75, RGYR2_AERPE;  O67226, RGYR2_AQUAE;
DR   Q97ZF5, RGYR2_SULSO;  Q975P6, RGYR2_SULTO;  O29238, RGYR_ARCFU ;
DR   Q58907, RGYR_METJA ;  Q9UZ86, RGYR_PYRAB ;  Q8ZXT5, RGYR_PYRAE ;
DR   P95479, RGYR_PYRFU ;  O58530, RGYR_PYRHO ;  Q6F598, RGYR_PYRKO ;
DR   Q08582, RGYR_SULAC ;  P74759, RGYR_SULSH ;  O51934, RGYR_THEMA ;
DR   Q8R979, RGYR_THETN ;  O42130, TOP2A_CHICK;  P41515, TOP2A_CRIGR;
DR   P11388, TOP2A_HUMAN;  Q01320, TOP2A_MOUSE;  O46374, TOP2A_PIG  ;
DR   P41516, TOP2A_RAT  ;  O42131, TOP2B_CHICK;  Q64399, TOP2B_CRILO;
DR   Q02880, TOP2B_HUMAN;  Q64511, TOP2B_MOUSE;  P34534, TOP2M_CAEEL;
DR   P90520, TOP2M_DICDI;  P30182, TOP2_ARATH ;  Q00942, TOP2_ASFB7 ;
DR   P0C9C2, TOP2_ASFK5 ;  P34203, TOP2_ASFM2 ;  P0C9C0, TOP2_ASFP4 ;
DR   P0C9C1, TOP2_ASFWA ;  O16140, TOP2_BOMMO ;  Q23670, TOP2_CAEEL ;
DR   P87078, TOP2_CANAL ;  O93794, TOP2_CANGA ;  P27570, TOP2_CRIFA ;
DR   Q55BP5, TOP2_DICDI ;  P15348, TOP2_DROME ;  Q196X4, TOP2_IIV3  ;
DR   Q9QSK1, TOP2_IIV6  ;  O61078, TOP2_LEICH ;  Q5UQE6, TOP2_MIMIV ;
DR   O24308, TOP2_PEA   ;  Q9Y8G8, TOP2_PENCH ;  Q01879, TOP2_PICGU ;
DR   P41001, TOP2_PLAFK ;  P08096, TOP2_SCHPO ;  P12531, TOP2_TRYBB ;
DR   P30190, TOP2_TRYCR ;  P06786, TOP2_YEAST ;  P07065, TOP5_BPT4  ;
DR   Q9YE67, TOP6A_AERPE;  O29322, TOP6A_ARCFU;  Q5V4R4, TOP6A_HALMA;
DR   B0R4D2, TOP6A_HALS3;  Q9HR32, TOP6A_HALSA;  A2BLE8, TOP6A_HYPBU;
DR   Q8TQF8, TOP6A_METAC;  Q468I6, TOP6A_METBF;  Q57815, TOP6A_METJA;
DR   Q8PUB7, TOP6A_METMA;  O27089, TOP6A_METTH;  Q3IPW7, TOP6A_NATPD;
DR   Q9V134, TOP6A_PYRAB;  Q8U0K9, TOP6A_PYRFU;  O59209, TOP6A_PYRHO;
DR   Q5JH82, TOP6A_PYRKO;  O05208, TOP6A_SULSH;  Q971T1, TOP6A_SULTO;
DR   Q9YE64, TOP6B_AERPE;  Q9C5V6, TOP6B_ARATH;  O29605, TOP6B_ARCFU;
DR   Q5V4R5, TOP6B_HALMA;  B0R4D3, TOP6B_HALS3;  Q9HR31, TOP6B_HALSA;
DR   Q8TQF7, TOP6B_METAC;  Q468I5, TOP6B_METBF;  Q12WQ0, TOP6B_METBU;
DR   Q58434, TOP6B_METJA;  Q8PUB8, TOP6B_METMA;  A4YHK7, TOP6B_METS5;
DR   O27088, TOP6B_METTH;  Q3IPW6, TOP6B_NATPD;  Q9V135, TOP6B_PYRAB;
DR   Q8ZVM0, TOP6B_PYRAE;  Q8U0K8, TOP6B_PYRFU;  O74020, TOP6B_PYRHO;
DR   Q5JH81, TOP6B_PYRKO;  C3N5B3, TOP6B_SULIA;  C4KGX9, TOP6B_SULIK;
DR   C3MPN7, TOP6B_SULIL;  C3MYN1, TOP6B_SULIM;  C3NHT6, TOP6B_SULIN;
DR   C3NDW7, TOP6B_SULIY;  O05207, TOP6B_SULSH;  Q97ZF0, TOP6B_SULSO;
DR   Q971T2, TOP6B_SULTO;  C5A6R5, TOP6B_THEGJ;  B6YVS9, TOP6B_THEON;
DR   C6A3G4, TOP6B_THESM;  P09176, TOPL_BPT4  ;  P23992, TOPS_BPT4  ;
//
ID   5.99.1.4
DE   2-hydroxychromene-2-carboxylate isomerase.
AN   2HC2CA isomerase.
AN   HCCA isomerase.
CA   2-hydroxy-2H-chromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-
CA   3-enoate.
CC   -!- This enzyme is involved in naphthalene degradation.
//
ID   6.1.1.1
DE   Tyrosine--tRNA ligase.
AN   L-tyrosine-tRNA(Tyr) ligase (AMP-forming).
AN   Tyrosine translase.
AN   Tyrosine tRNA synthetase.
AN   Tyrosine-transfer ribonucleate synthetase.
AN   Tyrosine-transfer RNA ligase.
AN   Tyrosyl-transfer ribonucleate synthetase.
AN   Tyrosyl-transfer ribonucleic acid synthetase.
AN   Tyrosyl-transfer RNA synthetase.
AN   Tyrosyl-tRNA ligase.
AN   Tyrosyl-tRNA synthetase.
CA   ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + L-tyrosyl-tRNA(Tyr).
PR   PROSITE; PDOC00161;
DR   Q81KS9, SYY1_BACAN ;  Q72Z73, SYY1_BACC1 ;  Q817A2, SYY1_BACCR ;
DR   Q633D2, SYY1_BACCZ ;  Q6HCM0, SYY1_BACHK ;  Q65G35, SYY1_BACLD ;
DR   P22326, SYY1_BACSU ;  Q97LC5, SYY1_CLOAB ;  Q838D7, SYY1_ENTFA ;
DR   Q7N3W6, SYY1_PHOLL ;  Q9HWP3, SYY1_PSEAE ;  Q3II62, SYY1_PSEHT ;
DR   Q8ZYT7, SYY1_PYRAE ;  Q5LXV1, SYY1_STRT1 ;  Q5M2F3, SYY1_STRT2 ;
DR   Q9KUQ0, SYY1_VIBCH ;  Q87J85, SYY1_VIBPA ;  Q8D5N2, SYY1_VIBVU ;
DR   Q7MCN7, SYY1_VIBVY ;  Q81XC6, SYY2_BACAN ;  Q72Y10, SYY2_BACC1 ;
DR   Q815S0, SYY2_BACCR ;  Q631P9, SYY2_BACCZ ;  Q6HBJ0, SYY2_BACHK ;
DR   Q65MW0, SYY2_BACLD ;  P25151, SYY2_BACSU ;  Q97KY6, SYY2_CLOAB ;
DR   Q834C7, SYY2_ENTFA ;  Q7N9W0, SYY2_PHOLL ;  Q9I5Q3, SYY2_PSEAE ;
DR   Q3ILJ9, SYY2_PSEHT ;  Q8ZW77, SYY2_PYRAE ;  Q5LZR6, SYY2_STRT1 ;
DR   Q5M4D1, SYY2_STRT2 ;  Q9KU92, SYY2_VIBCH ;  Q87LY8, SYY2_VIBPA ;
DR   Q8DBX3, SYY2_VIBVU ;  Q7MHZ4, SYY2_VIBVY ;  Q29465, SYYC_BOVIN ;
DR   Q5ZJ08, SYYC_CHICK ;  Q6TGS6, SYYC_DANRE ;  Q8SRV7, SYYC_ENCCU ;
DR   B7XHC1, SYYC_ENTBH ;  P54577, SYYC_HUMAN ;  Q91WQ3, SYYC_MOUSE ;
DR   C4V6W1, SYYC_NOSCE ;  Q5R8T5, SYYC_PONAB ;  Q4KM49, SYYC_RAT   ;
DR   O14055, SYYC_SCHPO ;  Q7ZX51, SYYC_XENLA ;  Q6DIJ1, SYYC_XENTR ;
DR   P36421, SYYC_YEAST ;  Q54WD9, SYYM_DICDI ;  Q9W107, SYYM_DROME ;
DR   Q9Y2Z4, SYYM_HUMAN ;  Q8BYL4, SYYM_MOUSE ;  P12063, SYYM_NEUCR ;
DR   P28669, SYYM_PODAS ;  Q5I0L3, SYYM_RAT   ;  O74890, SYYM_SCHPO ;
DR   P48527, SYYM_YEAST ;  A9NHF4, SYY_ACHLI  ;  Q6FG10, SYY_ACIAD  ;
DR   A0LUB6, SYY_ACIC1  ;  A0KFT8, SYY_AERHH  ;  Q9YA64, SYY_AERPE  ;
DR   Q8UED2, SYY_AGRT5  ;  B6EHW3, SYY_ALISL  ;  B3ERY6, SYY_AMOA5  ;
DR   B8JFS8, SYY_ANAD2  ;  Q2IPT7, SYY_ANADE  ;  Q5P9K5, SYY_ANAMM  ;
DR   Q2GIN1, SYY_ANAPZ  ;  B4UGQ8, SYY_ANASK  ;  Q3MEN7, SYY_ANAVT  ;
DR   O67632, SYY_AQUAE  ;  O29482, SYY_ARCFU  ;  Q5P7U2, SYY_AROAE  ;
DR   Q2NJG7, SYY_AYWBP  ;  A7Z7R1, SYY_BACA2  ;  P04077, SYY_BACCA  ;
DR   Q5LJ19, SYY_BACFN  ;  Q650K7, SYY_BACFR  ;  Q9K7X9, SYY_BACHD  ;
DR   A8FGA6, SYY_BACP2  ;  Q5WEB8, SYY_BACSK  ;  Q8A2S5, SYY_BACTN  ;
DR   A6KZL8, SYY_BACV8  ;  Q6G3B6, SYY_BARHE  ;  Q6FZW4, SYY_BARQU  ;
DR   Q6MNQ2, SYY_BDEBA  ;  B2IAX9, SYY_BEII9  ;  B8DU64, SYY_BIFA0  ;
DR   A1A1W2, SYY_BIFAA  ;  B3DSX9, SYY_BIFLD  ;  Q8G5G1, SYY_BIFLO  ;
DR   B7GTN2, SYY_BIFLS  ;  Q7VR52, SYY_BLOFL  ;  Q492T7, SYY_BLOPB  ;
DR   Q2KV13, SYY_BORA1  ;  Q0SNE3, SYY_BORAP  ;  Q7WFD0, SYY_BORBR  ;
DR   O51343, SYY_BORBU  ;  B7J1U2, SYY_BORBZ  ;  B5RLQ9, SYY_BORDL  ;
DR   Q661P9, SYY_BORGA  ;  B2S074, SYY_BORHD  ;  Q7W3Z8, SYY_BORPA  ;
DR   Q7VUW5, SYY_BORPE  ;  B5RRH9, SYY_BORRA  ;  A1QZF9, SYY_BORT9  ;
DR   Q89M63, SYY_BRAJA  ;  Q2YNR0, SYY_BRUA2  ;  Q57DI5, SYY_BRUAB  ;
DR   Q8YGV8, SYY_BRUME  ;  Q8G105, SYY_BRUSU  ;  B8D8S2, SYY_BUCA5  ;
DR   P57221, SYY_BUCAI  ;  Q8KA14, SYY_BUCAP  ;  B8D726, SYY_BUCAT  ;
DR   Q89AW3, SYY_BUCBP  ;  Q62HB4, SYY_BURMA  ;  Q3JNS0, SYY_BURP1  ;
DR   Q63QX0, SYY_BURPS  ;  Q39JJ6, SYY_BURS3  ;  Q2SZ62, SYY_BURTA  ;
DR   Q9PN27, SYY_CAMJE  ;  Q5HTJ2, SYY_CAMJR  ;  Q3ABU4, SYY_CARHZ  ;
DR   B8GWL9, SYY_CAUCN  ;  Q9A756, SYY_CAUCR  ;  B0SXC3, SYY_CAUSK  ;
DR   Q5L661, SYY_CHLAB  ;  Q3ARF2, SYY_CHLCH  ;  Q823H9, SYY_CHLCV  ;
DR   Q9PKX8, SYY_CHLMU  ;  Q9Z8I2, SYY_CHLPN  ;  B0B9H0, SYY_CHLT2  ;
DR   Q3KMV9, SYY_CHLTA  ;  B0BB49, SYY_CHLTB  ;  Q8KEW9, SYY_CHLTE  ;
DR   O84065, SYY_CHLTR  ;  Q7NTI2, SYY_CHRVO  ;  A8AH18, SYY_CITK8  ;
DR   A7FYR9, SYY_CLOB1  ;  C3KUT7, SYY_CLOB6  ;  A6M293, SYY_CLOB8  ;
DR   B2UYM8, SYY_CLOBA  ;  B2TQ95, SYY_CLOBB  ;  A5I748, SYY_CLOBH  ;
DR   C1FLY1, SYY_CLOBJ  ;  B1IFG0, SYY_CLOBK  ;  A7GIQ9, SYY_CLOBL  ;
DR   B1L203, SYY_CLOBM  ;  B9DZQ6, SYY_CLOK1  ;  A5N680, SYY_CLOK5  ;
DR   Q0TTF4, SYY_CLOP1  ;  Q8XMN6, SYY_CLOPE  ;  A9KMS8, SYY_CLOPH  ;
DR   Q0SVA4, SYY_CLOPS  ;  Q891D3, SYY_CLOTE  ;  A3DDC9, SYY_CLOTH  ;
DR   Q47V01, SYY_COLP3  ;  Q6NHG2, SYY_CORDI  ;  Q8FTM1, SYY_COREF  ;
DR   Q8NQM8, SYY_CORGL  ;  Q4JVY5, SYY_CORJK  ;  Q83EX7, SYY_COXBU  ;
DR   Q475S5, SYY_CUPPJ  ;  Q11UV9, SYY_CYTH3  ;  Q47B76, SYY_DECAR  ;
DR   Q3Z8V6, SYY_DEHE1  ;  Q3ZX03, SYY_DEHSC  ;  Q9RR63, SYY_DEIRA  ;
DR   B8FGS9, SYY_DESAA  ;  Q316W7, SYY_DESDG  ;  B8G0N6, SYY_DESHD  ;
DR   Q251G4, SYY_DESHY  ;  A8ZUK6, SYY_DESOH  ;  Q6AJ82, SYY_DESPS  ;
DR   Q72DH6, SYY_DESVH  ;  A8LQM0, SYY_DINSH  ;  A7ZM99, SYY_ECO24  ;
DR   B7URX8, SYY_ECO27  ;  B7M9Z1, SYY_ECO45  ;  B7L5J0, SYY_ECO55  ;
DR   P0AGK0, SYY_ECO57  ;  B5Z471, SYY_ECO5E  ;  B7NTZ5, SYY_ECO7I  ;
DR   B7MVB5, SYY_ECO81  ;  B7M0J4, SYY_ECO8A  ;  C4ZYA0, SYY_ECOBW  ;
DR   B1XFU9, SYY_ECODH  ;  A8A0I0, SYY_ECOHS  ;  A1ABI2, SYY_ECOK1  ;
DR   Q8FH88, SYY_ECOL6  ;  B1IQB7, SYY_ECOLC  ;  P0AGJ9, SYY_ECOLI  ;
DR   B7NB91, SYY_ECOLU  ;  B6IB76, SYY_ECOSE  ;  B1LEP9, SYY_ECOSM  ;
DR   Q1RBF8, SYY_ECOUT  ;  Q3YT49, SYY_EHRCJ  ;  Q2GI13, SYY_EHRCR  ;
DR   Q5FF40, SYY_EHRRG  ;  Q5HCB5, SYY_EHRRW  ;  A4W9W0, SYY_ENT38  ;
DR   A7MMK1, SYY_ENTS8  ;  Q6D5V2, SYY_ERWCT  ;  B2VEN3, SYY_ERWT9  ;
DR   B7LQN3, SYY_ESCF3  ;  A5FMI1, SYY_FLAJ1  ;  A6GW04, SYY_FLAPJ  ;
DR   Q5NGY5, SYY_FRATT  ;  Q8RH57, SYY_FUSNN  ;  Q5KW48, SYY_GEOKA  ;
DR   Q39WF4, SYY_GEOMG  ;  P00952, SYY_GEOSE  ;  Q74E25, SYY_GEOSL  ;
DR   Q7ND21, SYY_GLOVI  ;  Q5FR80, SYY_GLUOX  ;  Q7VN81, SYY_HAEDU  ;
DR   Q4QL45, SYY_HAEI8  ;  P43836, SYY_HAEIN  ;  Q2S8Y9, SYY_HAHCH  ;
DR   B9LTA6, SYY_HALLT  ;  Q5V4J1, SYY_HALMA  ;  B0R7E0, SYY_HALS3  ;
DR   Q9HN62, SYY_HALSA  ;  C4K4B6, SYY_HAMD5  ;  Q7VHY1, SYY_HELHP  ;
DR   Q9ZL69, SYY_HELPJ  ;  P56417, SYY_HELPY  ;  Q5QVP5, SYY_IDILO  ;
DR   A6WCS8, SYY_KINRD  ;  B5XWP0, SYY_KLEP3  ;  A6T9Y5, SYY_KLEP7  ;
DR   Q5FMI6, SYY_LACAC  ;  Q7B9Y9, SYY_LACBR  ;  Q1GBW9, SYY_LACDA  ;
DR   Q04CC7, SYY_LACDB  ;  B2GF15, SYY_LACF3  ;  A8YX30, SYY_LACH4  ;
DR   Q74LL0, SYY_LACJO  ;  Q9CIH5, SYY_LACLA  ;  A2RIB1, SYY_LACLM  ;
DR   Q031T7, SYY_LACLS  ;  Q88TV5, SYY_LACPL  ;  A5VHU6, SYY_LACRD  ;
DR   Q1WSF8, SYY_LACS1  ;  Q38XK7, SYY_LACSS  ;  C1DCW5, SYY_LARHH  ;
DR   Q5X7H7, SYY_LEGPA  ;  Q5ZY07, SYY_LEGPH  ;  Q5WYX4, SYY_LEGPL  ;
DR   Q6AGC2, SYY_LEIXX  ;  Q72RP6, SYY_LEPIC  ;  Q8F411, SYY_LEPIN  ;
DR   B1MW54, SYY_LEUCK  ;  Q03UK8, SYY_LEUMM  ;  Q92BB1, SYY_LISIN  ;
DR   C1KVP5, SYY_LISMC  ;  Q71Z70, SYY_LISMF  ;  B8DHE4, SYY_LISMH  ;
DR   Q8Y6T4, SYY_LISMO  ;  A0AJ48, SYY_LISW6  ;  B9E7E5, SYY_MACCJ  ;
DR   Q2W2T6, SYY_MAGSA  ;  Q65T71, SYY_MANSM  ;  Q6F0M8, SYY_MESFL  ;
DR   Q8TSI1, SYY_METAC  ;  Q46BQ5, SYY_METBF  ;  Q12W06, SYY_METBU  ;
DR   Q60AU5, SYY_METCA  ;  Q2FNA1, SYY_METHJ  ;  Q57834, SYY_METJA  ;
DR   Q8TXZ2, SYY_METKA  ;  A2SU89, SYY_METLZ  ;  Q8PVK0, SYY_METMA  ;
DR   A3CYG9, SYY_METMJ  ;  Q6M0K7, SYY_METMP  ;  A5UKJ0, SYY_METS3  ;
DR   B8EI82, SYY_METSB  ;  Q2NHE1, SYY_METST  ;  O27795, SYY_METTH  ;
DR   A6URQ1, SYY_METVS  ;  Q5UPJ7, SYY_MIMIV  ;  Q2RHS8, SYY_MOOTA  ;
DR   A5IZH1, SYY_MYCAP  ;  P67612, SYY_MYCBO  ;  Q2SRK6, SYY_MYCCT  ;
DR   Q9EUU8, SYY_MYCFO  ;  Q7NBH9, SYY_MYCGA  ;  P47693, SYY_MYCGE  ;
DR   Q601Y5, SYY_MYCH2  ;  Q4A8U9, SYY_MYCH7  ;  Q4AAX3, SYY_MYCHJ  ;
DR   Q49900, SYY_MYCLE  ;  Q6KH97, SYY_MYCMO  ;  Q6MST3, SYY_MYCMS  ;
DR   Q740F5, SYY_MYCPA  ;  Q8EUX2, SYY_MYCPE  ;  P75122, SYY_MYCPN  ;
DR   Q98Q81, SYY_MYCPU  ;  Q4A5E2, SYY_MYCS5  ;  A3Q0S2, SYY_MYCSJ  ;
DR   A1UH85, SYY_MYCSK  ;  Q1B7S2, SYY_MYCSS  ;  P67611, SYY_MYCTU  ;
DR   Q74MD3, SYY_NANEQ  ;  Q3IQU8, SYY_NATPD  ;  Q5FAF7, SYY_NEIG1  ;
DR   B4RP13, SYY_NEIG2  ;  A9M1J5, SYY_NEIM0  ;  Q9JVY6, SYY_NEIMA  ;
DR   Q9JXY5, SYY_NEIMB  ;  A1KS60, SYY_NEIMF  ;  Q82UQ1, SYY_NITEU  ;
DR   Q2YBR1, SYY_NITMU  ;  Q3JCM3, SYY_NITOC  ;  Q3SS12, SYY_NITWN  ;
DR   Q5YYA4, SYY_NOCFA  ;  Q8YSU9, SYY_NOSS1  ;  Q2G6I4, SYY_NOVAD  ;
DR   Q8CXA5, SYY_OCEIH  ;  Q04D20, SYY_OENOB  ;  Q6YQA6, SYY_ONYPE  ;
DR   B1ZUZ4, SYY_OPITP  ;  A5CC73, SYY_ORITB  ;  B3CV32, SYY_ORITI  ;
DR   A6LGF1, SYY_PARD8  ;  A1B3B3, SYY_PARDP  ;  Q6MC06, SYY_PARUW  ;
DR   Q9CMQ8, SYY_PASMU  ;  C6DK25, SYY_PECCP  ;  Q03HI6, SYY_PEDPA  ;
DR   Q3A220, SYY_PELCD  ;  Q3B5D0, SYY_PELLD  ;  Q4FMN5, SYY_PELUB  ;
DR   Q6LUR9, SYY_PHOPR  ;  B1VAA7, SYY_PHYAS  ;  B3R0D7, SYY_PHYMT  ;
DR   Q6L2J1, SYY_PICTO  ;  B2RHN4, SYY_PORG3  ;  Q7MXD8, SYY_PORGI  ;
DR   Q6A7W0, SYY_PROAC  ;  Q319F8, SYY_PROM9  ;  Q7VAP7, SYY_PROMA  ;
DR   Q7TUT0, SYY_PROMM  ;  Q7V0D7, SYY_PROMP  ;  Q46JD7, SYY_PROMT  ;
DR   Q48NN3, SYY_PSE14  ;  A6UZV3, SYY_PSEA7  ;  B7V6L2, SYY_PSEA8  ;
DR   Q02SV2, SYY_PSEAB  ;  Q4K517, SYY_PSEF5  ;  Q3K5W9, SYY_PSEPF  ;
DR   Q88QQ2, SYY_PSEPK  ;  Q889Y8, SYY_PSESM  ;  Q4ZMM7, SYY_PSEU2  ;
DR   Q4FQ91, SYY_PSYA2  ;  Q9V027, SYY_PYRAB  ;  A4WN67, SYY_PYRAR  ;
DR   A3MXW0, SYY_PYRCJ  ;  Q8U2H3, SYY_PYRFU  ;  O58739, SYY_PYRHO  ;
DR   A1RSH9, SYY_PYRIL  ;  Q5JF63, SYY_PYRKO  ;  Q8Y240, SYY_RALSO  ;
DR   Q98NS5, SYY_RHILO  ;  Q92PK5, SYY_RHIME  ;  Q7UM14, SYY_RHOBA  ;
DR   Q6N703, SYY_RHOPA  ;  Q2RSR3, SYY_RHORT  ;  A3PIU9, SYY_RHOS1  ;
DR   Q3J3I3, SYY_RHOS4  ;  A4WR15, SYY_RHOS5  ;  B9KQU0, SYY_RHOSK  ;
DR   C3PNX7, SYY_RICAE  ;  A8GNW7, SYY_RICAH  ;  Q1RI22, SYY_RICBR  ;
DR   A8EYE9, SYY_RICCK  ;  Q92HE8, SYY_RICCN  ;  Q4UL45, SYY_RICFE  ;
DR   A8F228, SYY_RICM5  ;  Q9ZCZ4, SYY_RICPR  ;  C4K0N9, SYY_RICPU  ;
DR   B0BY69, SYY_RICRO  ;  A8GSQ1, SYY_RICRS  ;  Q68WH9, SYY_RICTY  ;
DR   A7NK64, SYY_ROSCS  ;  Q164D9, SYY_ROSDO  ;  A5UUZ9, SYY_ROSS1  ;
DR   B5F6J8, SYY_SALA4  ;  A9MEH2, SYY_SALAR  ;  Q57PI8, SYY_SALCH  ;
DR   B5FIF4, SYY_SALDC  ;  B5QV10, SYY_SALEP  ;  B5RAL0, SYY_SALG2  ;
DR   B4THC6, SYY_SALHS  ;  B4T586, SYY_SALNS  ;  Q5PIK7, SYY_SALPA  ;
DR   A9N034, SYY_SALPB  ;  C0Q5T3, SYY_SALPC  ;  B5BKC0, SYY_SALPK  ;
DR   Q2S238, SYY_SALRD  ;  B4TV08, SYY_SALSV  ;  Q8XG70, SYY_SALTI  ;
DR   Q7CQK7, SYY_SALTY  ;  A8GDY0, SYY_SERP5  ;  Q8EHB3, SYY_SHEON  ;
DR   B2U2D7, SYY_SHIB3  ;  Q320Z4, SYY_SHIBS  ;  Q32FD6, SYY_SHIDS  ;
DR   Q0T4E0, SYY_SHIF8  ;  Q83KY0, SYY_SHIFL  ;  Q3Z1Z3, SYY_SHISS  ;
DR   Q5LQK5, SYY_SILPO  ;  Q1GI60, SYY_SILST  ;  Q2NT02, SYY_SODGM  ;
DR   A7X3G2, SYY_STAA1  ;  A6U2J5, SYY_STAA2  ;  Q2FG09, SYY_STAA3  ;
DR   Q2FXJ5, SYY_STAA8  ;  A5ITQ1, SYY_STAA9  ;  Q2YTG1, SYY_STAAB  ;
DR   Q5HF45, SYY_STAAC  ;  A6QHR2, SYY_STAAE  ;  Q99TD5, SYY_STAAM  ;
DR   Q7A537, SYY_STAAN  ;  Q6GFX9, SYY_STAAR  ;  Q6G8J9, SYY_STAAS  ;
DR   A8Z2P6, SYY_STAAT  ;  Q7A0M7, SYY_STAAW  ;  B9DN75, SYY_STACT  ;
DR   Q5HNH6, SYY_STAEQ  ;  Q8CS48, SYY_STAES  ;  Q4L774, SYY_STAHJ  ;
DR   Q49YG2, SYY_STAS1  ;  Q3K3L4, SYY_STRA1  ;  Q8E7K0, SYY_STRA3  ;
DR   Q8E241, SYY_STRA5  ;  Q829F2, SYY_STRAW  ;  Q9RJ50, SYY_STRCO  ;
DR   C0M6G7, SYY_STRE4  ;  B4U045, SYY_STREM  ;  A8AZI5, SYY_STRGC  ;
DR   B1W1W0, SYY_STRGG  ;  Q8DS44, SYY_STRMU  ;  Q9A1U3, SYY_STRP1  ;
DR   Q04I74, SYY_STRP2  ;  P0DG62, SYY_STRP3  ;  B5E3A7, SYY_STRP4  ;
DR   Q5XE99, SYY_STRP6  ;  C1CAS7, SYY_STRP7  ;  Q8P2Y5, SYY_STRP8  ;
DR   Q1JE22, SYY_STRPB  ;  Q1JNY0, SYY_STRPC  ;  Q1JJ25, SYY_STRPD  ;
DR   Q1J8X3, SYY_STRPF  ;  A2RC49, SYY_STRPG  ;  B1I9G6, SYY_STRPI  ;
DR   B8ZPM2, SYY_STRPJ  ;  Q48VR3, SYY_STRPM  ;  Q97NE3, SYY_STRPN  ;
DR   P0DG63, SYY_STRPQ  ;  B2IN18, SYY_STRPS  ;  B5XJ70, SYY_STRPZ  ;
DR   Q8DN52, SYY_STRR6  ;  A4VYU1, SYY_STRS2  ;  C0MEE0, SYY_STRS7  ;
DR   Q03IK0, SYY_STRTD  ;  B9DSZ3, SYY_STRU0  ;  C1CH28, SYY_STRZJ  ;
DR   C1CN46, SYY_STRZP  ;  C1CU03, SYY_STRZT  ;  Q4JCH6, SYY_SULAC  ;
DR   Q30SN2, SYY_SULDN  ;  C3N048, SYY_SULIA  ;  C4KJ87, SYY_SULIK  ;
DR   C3MJP1, SYY_SULIL  ;  C3MYZ9, SYY_SULIM  ;  C3NMQ6, SYY_SULIN  ;
DR   C3N8R2, SYY_SULIY  ;  P95982, SYY_SULSO  ;  Q96YV3, SYY_SULTO  ;
DR   Q67QD6, SYY_SYMTH  ;  Q2LR98, SYY_SYNAS  ;  Q31K19, SYY_SYNE7  ;
DR   Q2JSX8, SYY_SYNJA  ;  Q2JIV0, SYY_SYNJB  ;  Q5N1U0, SYY_SYNP6  ;
DR   Q7TTW9, SYY_SYNPX  ;  Q3AZE2, SYY_SYNS9  ;  Q3AHU0, SYY_SYNSC  ;
DR   P73141, SYY_SYNY3  ;  Q9HKT3, SYY_THEAC  ;  Q8DMR1, SYY_THEEB  ;
DR   Q47N93, SYY_THEFY  ;  C5A5R0, SYY_THEGJ  ;  Q9WYU8, SYY_THEMA  ;
DR   B6YWK6, SYY_THEON  ;  C6A0Z6, SYY_THESM  ;  P83453, SYY_THET2  ;
DR   Q5SIH0, SYY_THET8  ;  Q8R6V5, SYY_THETN  ;  Q979Z1, SYY_THEVO  ;
DR   Q31E84, SYY_THICR  ;  Q3SLJ8, SYY_THIDA  ;  P41256, SYY_THIFE  ;
DR   Q73PD8, SYY_TREDE  ;  O83806, SYY_TREPA  ;  Q83HH5, SYY_TROW8  ;
DR   Q83GS7, SYY_TROWT  ;  B1AIA6, SYY_UREP2  ;  Q9PR27, SYY_UREPA  ;
DR   B5ZAU9, SYY_UREU1  ;  Q5E424, SYY_VIBF1  ;  B5FFR9, SYY_VIBFM  ;
DR   Q8D2L6, SYY_WIGBR  ;  Q73G50, SYY_WOLPM  ;  B3CM50, SYY_WOLPP  ;
DR   Q7MAH6, SYY_WOLSU  ;  Q5GT37, SYY_WOLTR  ;  C0R4X5, SYY_WOLWR  ;
DR   Q8PFT1, SYY_XANAC  ;  Q3BNC2, SYY_XANC5  ;  Q4UPQ9, SYY_XANC8  ;
DR   Q8P475, SYY_XANCP  ;  Q2P892, SYY_XANOM  ;  Q5H5K1, SYY_XANOR  ;
DR   A7INU9, SYY_XANP2  ;  Q9PGX7, SYY_XYLFA  ;  Q87F06, SYY_XYLFT  ;
DR   A1JNV3, SYY_YERE8  ;  A7FHM0, SYY_YERP3  ;  Q1C791, SYY_YERPA  ;
DR   B2K5H0, SYY_YERPB  ;  Q8ZE20, SYY_YERPE  ;  A9QZ95, SYY_YERPG  ;
DR   Q1CIM5, SYY_YERPN  ;  A4TIS1, SYY_YERPP  ;  Q66A49, SYY_YERPS  ;
DR   B1JJR1, SYY_YERPY  ;  Q5NLZ3, SYY_ZYMMO  ;
//
ID   6.1.1.2
DE   Tryptophan--tRNA ligase.
AN   L-tryptophan-tRNA(Trp) ligase (AMP-forming).
AN   TrpRS.
AN   Tryptophan translase.
AN   Tryptophanyl ribonucleic synthetase.
AN   Tryptophanyl-transfer ribonucleate synthetase.
AN   Tryptophanyl-transfer ribonucleic acid synthetase.
AN   Tryptophanyl-transfer ribonucleic synthetase.
AN   Tryptophanyl-transfer RNA synthetase.
AN   Tryptophanyl-tRNA synthase.
AN   Tryptophanyl-tRNA synthetase.
CA   ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl-
CA   tRNA(Trp).
PR   PROSITE; PDOC00161;
DR   Q9HN83, SYW1_HALSA ;  Q82HU1, SYW1_STRAW ;  Q8CJX0, SYW1_STRCO ;
DR   Q9RVD6, SYW2_DEIRA ;  Q9HN66, SYW2_HALSA ;  Q82E91, SYW2_STRAW ;
DR   Q9KZA7, SYW2_STRCO ;  P17248, SYWC_BOVIN ;  Q55DZ8, SYWC_DICDI ;
DR   P23381, SYWC_HUMAN ;  P32921, SYWC_MOUSE ;  Q5R4J1, SYWC_PONAB ;
DR   P23612, SYWC_RABIT ;  Q6P7B0, SYWC_RAT   ;  Q09692, SYWC_SCHPO ;
DR   Q12109, SYWC_YEAST ;  Q3T099, SYWM_BOVIN ;  P46579, SYWM_CAEEL ;
DR   Q86A90, SYWM_DICDI ;  Q9UGM6, SYWM_HUMAN ;  Q9CYK1, SYWM_MOUSE ;
DR   O42875, SYWM_SCHPO ;  P04803, SYWM_YEAST ;  Q9Y924, SYW_AERPE  ;
DR   Q8UIE8, SYW_AGRT5  ;  O67115, SYW_AQUAE  ;  O28579, SYW_ARCFU  ;
DR   Q81TS6, SYW_BACAN  ;  Q9K8Y2, SYW_BACHD  ;  P21656, SYW_BACSU  ;
DR   Q7VRN5, SYW_BLOFL  ;  Q7WGI7, SYW_BORBR  ;  O51038, SYW_BORBU  ;
DR   Q7W5T6, SYW_BORPA  ;  Q7VZ05, SYW_BORPE  ;  Q89W91, SYW_BRAJA  ;
DR   P67586, SYW_BRUME  ;  P67587, SYW_BRUSU  ;  P57602, SYW_BUCAI  ;
DR   Q8K941, SYW_BUCAP  ;  P59466, SYW_BUCBP  ;  Q9PIB4, SYW_CAMJE  ;
DR   Q5HW79, SYW_CAMJR  ;  Q9AC05, SYW_CAUCR  ;  Q821H9, SYW_CHLCV  ;
DR   Q9PJF5, SYW_CHLMU  ;  Q9Z7A4, SYW_CHLPN  ;  O84589, SYW_CHLTR  ;
DR   Q97LD6, SYW_CLOAB  ;  Q46127, SYW_CLOLO  ;  Q8XMQ5, SYW_CLOPE  ;
DR   Q891C7, SYW_CLOTE  ;  Q8FRR3, SYW_COREF  ;  Q8NSJ4, SYW_CORGL  ;
DR   Q9RWV7, SYW_DEIRA  ;  P67589, SYW_ECO57  ;  P67588, SYW_ECOL6  ;
DR   P00954, SYW_ECOLI  ;  O96771, SYW_ENCCU  ;  Q9EYY6, SYW_ENTAE  ;
DR   Q830U2, SYW_ENTFA  ;  Q8RGA3, SYW_FUSNN  ;  P00953, SYW_GEOSE  ;
DR   Q7NCG8, SYW_GLOVI  ;  Q7VPB2, SYW_HAEDU  ;  P43835, SYW_HAEIN  ;
DR   Q7VIP6, SYW_HELHP  ;  Q9ZJX4, SYW_HELPJ  ;  P56396, SYW_HELPY  ;
DR   A2BLD4, SYW_HYPBU  ;  Q9CJD1, SYW_LACLA  ;  Q6AGQ7, SYW_LEIXX  ;
DR   Q929H5, SYW_LISIN  ;  Q71XG7, SYW_LISMF  ;  Q8Y577, SYW_LISMO  ;
DR   Q8TUA1, SYW_METAC  ;  Q58810, SYW_METJA  ;  Q8TYF7, SYW_METKA  ;
DR   Q8PWV5, SYW_METMA  ;  O26352, SYW_METTH  ;  P67591, SYW_MYCBO  ;
DR   Q7NAT8, SYW_MYCGA  ;  P47372, SYW_MYCGE  ;  Q49901, SYW_MYCLE  ;
DR   Q8EVV1, SYW_MYCPE  ;  P75510, SYW_MYCPN  ;  Q98PH7, SYW_MYCPU  ;
DR   P67590, SYW_MYCTU  ;  Q9JTQ0, SYW_NEIMA  ;  Q9JYQ9, SYW_NEIMB  ;
DR   Q8YXE4, SYW_NOSS1  ;  Q8ERU2, SYW_OCEIH  ;  P57956, SYW_PASMU  ;
DR   Q7NA61, SYW_PHOLL  ;  Q7MT94, SYW_PORGI  ;  Q7VBM9, SYW_PROMA  ;
DR   Q7TV34, SYW_PROMM  ;  Q7V286, SYW_PROMP  ;  Q9HVX6, SYW_PSEAE  ;
DR   Q88NA1, SYW_PSEPK  ;  Q87WW4, SYW_PSESM  ;  Q9UY11, SYW_PYRAB  ;
DR   Q8ZTU5, SYW_PYRAE  ;  A4WL99, SYW_PYRAR  ;  A3MX72, SYW_PYRCJ  ;
DR   Q8U453, SYW_PYRFU  ;  O59584, SYW_PYRHO  ;  Q5JEP3, SYW_PYRKO  ;
DR   Q8Y0A1, SYW_RALSO  ;  Q98C31, SYW_RHILO  ;  Q92SI9, SYW_RHIME  ;
DR   Q7UQA4, SYW_RHOBA  ;  Q1RIE3, SYW_RICBR  ;  Q92HR1, SYW_RICCN  ;
DR   Q4UL98, SYW_RICFE  ;  Q9ZD76, SYW_RICPR  ;  Q68WR2, SYW_RICTY  ;
DR   P0A2P3, SYW_SALTI  ;  P0A2P2, SYW_SALTY  ;  Q8EK12, SYW_SHEON  ;
DR   Q83JA5, SYW_SHIFL  ;  Q5HH88, SYW_STAAC  ;  P67592, SYW_STAAM  ;
DR   P67593, SYW_STAAN  ;  Q6GI89, SYW_STAAR  ;  Q6GAT0, SYW_STAAS  ;
DR   P67594, SYW_STAAW  ;  Q5HQH4, SYW_STAEQ  ;  Q8CT69, SYW_STAES  ;
DR   Q8E2J5, SYW_STRA3  ;  Q8DWP7, SYW_STRA5  ;  Q8DRR1, SYW_STRMU  ;
DR   Q99XH4, SYW_STRP1  ;  P0DG60, SYW_STRP3  ;  Q5X9A2, SYW_STRP6  ;
DR   P67598, SYW_STRP8  ;  P67595, SYW_STRPN  ;  P0DG61, SYW_STRPQ  ;
DR   P67596, SYW_STRR6  ;  Q4JBG7, SYW_SULAC  ;  Q97ZX0, SYW_SULSO  ;
DR   Q976M1, SYW_SULTO  ;  Q7TTU9, SYW_SYNPX  ;  P73655, SYW_SYNY3  ;
DR   Q9HIW5, SYW_THEAC  ;  Q8DHG3, SYW_THEEB  ;  Q9WYW2, SYW_THEMA  ;
DR   B6YUH1, SYW_THEON  ;  C6A032, SYW_THESM  ;  Q8R9X8, SYW_THETN  ;
DR   Q978Y8, SYW_THEVO  ;  O83640, SYW_TREPA  ;  Q83HC3, SYW_TROW8  ;
DR   Q83FN1, SYW_TROWT  ;  Q9PQW8, SYW_UREPA  ;  Q9KNV7, SYW_VIBCH  ;
DR   Q5E2G5, SYW_VIBF1  ;  Q87L13, SYW_VIBPA  ;  Q8DCT6, SYW_VIBVU  ;
DR   Q7MH15, SYW_VIBVY  ;  Q8D1X5, SYW_WIGBR  ;  Q7MAE0, SYW_WOLSU  ;
DR   Q8PFH5, SYW_XANAC  ;  Q8P3Z4, SYW_XANCP  ;  Q9PG74, SYW_XYLFA  ;
DR   Q87B10, SYW_XYLFT  ;  Q8ZJF2, SYW_YERPE  ;
//
ID   6.1.1.3
DE   Threonine--tRNA ligase.
AN   Threonine translase.
AN   Threonyl-tRNA synthetase.
CA   ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr).
PR   PROSITE; PDOC00363;
DR   Q9YDW0, SYT1_AERPE ;  P18255, SYT1_BACSU ;  Q9YFY3, SYT2_AERPE ;
DR   P18256, SYT2_BACSU ;  Q54J66, SYTC1_DICDI;  A6QNM8, SYTC2_BOVIN;
DR   Q8MP20, SYTC2_DICDI;  A2RTX5, SYTC2_HUMAN;  Q8BLY2, SYTC2_MOUSE;
DR   Q0V9S0, SYTC2_XENTR;  Q8GZ45, SYTC_ARATH ;  Q3ZBV8, SYTC_BOVIN ;
DR   P52709, SYTC_CAEEL ;  Q8SRH2, SYTC_ENCCU ;  B7XIA1, SYTC_ENTBH ;
DR   P26639, SYTC_HUMAN ;  Q9D0R2, SYTC_MOUSE ;  Q5XHY5, SYTC_RAT   ;
DR   P87144, SYTC_SCHPO ;  P04801, SYTC_YEAST ;  O04630, SYTM_ARATH ;
DR   Q9BW92, SYTM_HUMAN ;  Q3UQ84, SYTM_MOUSE ;  Q68FW7, SYTM_RAT   ;
DR   O13969, SYTM_SCHPO ;  P07236, SYTM_YEAST ;  A9NF46, SYT_ACHLI  ;
DR   A1TR39, SYT_ACIAC  ;  Q6F860, SYT_ACIAD  ;  B7H005, SYT_ACIB3  ;
DR   B7I688, SYT_ACIB5  ;  B2HTH0, SYT_ACIBC  ;  B0VKJ4, SYT_ACIBS  ;
DR   A3M299, SYT_ACIBT  ;  B0V5P2, SYT_ACIBY  ;  C1F9K5, SYT_ACIC5  ;
DR   A5G0L2, SYT_ACICJ  ;  B9MHX8, SYT_ACIET  ;  B7J7T0, SYT_ACIF2  ;
DR   B5EN57, SYT_ACIF5  ;  A1W8I6, SYT_ACISJ  ;  A3MYU1, SYT_ACTP2  ;
DR   B3H061, SYT_ACTP7  ;  B0BSM2, SYT_ACTPJ  ;  A6VNZ2, SYT_ACTSZ  ;
DR   A0KKP9, SYT_AERHH  ;  A4SMA4, SYT_AERS4  ;  B9JFG4, SYT_AGRRK  ;
DR   Q8UEL1, SYT_AGRT5  ;  B9JWF4, SYT_AGRVS  ;  Q0AAL5, SYT_ALHEH  ;
DR   B4RSL8, SYT_ALTMD  ;  B8J823, SYT_ANAD2  ;  Q2IJC0, SYT_ANADE  ;
DR   B9KH76, SYT_ANAMF  ;  Q5P9F6, SYT_ANAMM  ;  B4UAM8, SYT_ANASK  ;
DR   B7GGN9, SYT_ANOFW  ;  O67583, SYT_AQUAE  ;  O29703, SYT_ARCFU  ;
DR   Q5P7X5, SYT_AROAE  ;  A1R735, SYT_ARTAT  ;  B8H9E8, SYT_ARTCA  ;
DR   A0JXC7, SYT_ARTS2  ;  Q2NIG3, SYT_AYWBP  ;  B6YQ95, SYT_AZOPC  ;
DR   A1K4E1, SYT_AZOSB  ;  C1DF42, SYT_AZOVD  ;  A7Z7I1, SYT_BACA2  ;
DR   Q5LEQ6, SYT_BACFN  ;  Q64VP2, SYT_BACFR  ;  Q9K866, SYT_BACHD  ;
DR   Q8AAP2, SYT_BACTN  ;  A6L7J7, SYT_BACV8  ;  A1USJ2, SYT_BARBK  ;
DR   Q6G3K1, SYT_BARHE  ;  Q6FZZ7, SYT_BARQU  ;  A9IVB0, SYT_BART1  ;
DR   Q1LT04, SYT_BAUCH  ;  Q6MML0, SYT_BDEBA  ;  B8DUF4, SYT_BIFA0  ;
DR   B3DRX5, SYT_BIFLD  ;  Q8G6C2, SYT_BIFLO  ;  B7GR13, SYT_BIFLS  ;
DR   Q2L2M5, SYT_BORA1  ;  Q0SMD6, SYT_BORAP  ;  Q7WKF7, SYT_BORBR  ;
DR   O51662, SYT_BORBU  ;  B7J0G5, SYT_BORBZ  ;  B5RMR3, SYT_BORDL  ;
DR   Q660F3, SYT_BORGA  ;  B2S162, SYT_BORHD  ;  Q7W912, SYT_BORPA  ;
DR   A9IRH6, SYT_BORPD  ;  Q7VY64, SYT_BORPE  ;  B5RQ59, SYT_BORRA  ;
DR   A1R0E4, SYT_BORT9  ;  B2S5S6, SYT_BRUA1  ;  Q2YQ07, SYT_BRUA2  ;
DR   Q57D65, SYT_BRUAB  ;  A9M582, SYT_BRUC2  ;  C0RJ44, SYT_BRUMB  ;
DR   Q8YH89, SYT_BRUME  ;  B0CGM0, SYT_BRUSI  ;  Q8G0L8, SYT_BRUSU  ;
DR   B8D8S6, SYT_BUCA5  ;  P57225, SYT_BUCAI  ;  P46244, SYT_BUCAP  ;
DR   B8D730, SYT_BUCAT  ;  P59554, SYT_BUCBP  ;  B1YP13, SYT_BURA4  ;
DR   B1K091, SYT_BURCC  ;  B4E7I6, SYT_BURCJ  ;  Q0BG06, SYT_BURCM  ;
DR   A9ABF9, SYT_BURM1  ;  A3MJT8, SYT_BURM7  ;  A2S2N6, SYT_BURM9  ;
DR   Q62KI2, SYT_BURMA  ;  A1V3R3, SYT_BURMS  ;  A3NUI4, SYT_BURP0  ;
DR   Q3JT13, SYT_BURP1  ;  A3N8T1, SYT_BURP6  ;  B2JJJ7, SYT_BURP8  ;
DR   B2SZG2, SYT_BURPP  ;  Q63TM2, SYT_BURPS  ;  Q39H55, SYT_BURS3  ;
DR   Q2SVD8, SYT_BURTA  ;  A4JDU4, SYT_BURVG  ;  Q13WF7, SYT_BURXL  ;
DR   A8MBZ5, SYT_CALMQ  ;  A7ZAZ7, SYT_CAMC1  ;  A7GVZ2, SYT_CAMC5  ;
DR   A7I107, SYT_CAMHC  ;  A8FK07, SYT_CAMJ8  ;  A7H1S0, SYT_CAMJD  ;
DR   Q9PIS3, SYT_CAMJE  ;  A1VXT5, SYT_CAMJJ  ;  Q5HWW3, SYT_CAMJR  ;
DR   B9KEB1, SYT_CAMLR  ;  Q3ABS6, SYT_CARHZ  ;  B8GZS7, SYT_CAUCN  ;
DR   Q9AAX8, SYT_CAUCR  ;  B0T0Z7, SYT_CAUSK  ;  B3PL16, SYT_CELJU  ;
DR   A0RU76, SYT_CENSY  ;  Q5L4T1, SYT_CHLAB  ;  Q3APV9, SYT_CHLCH  ;
DR   Q821I3, SYT_CHLCV  ;  Q256F9, SYT_CHLFF  ;  B3EEC1, SYT_CHLL2  ;
DR   Q9PJF9, SYT_CHLMU  ;  B3EKG9, SYT_CHLPB  ;  Q9Z7A0, SYT_CHLPN  ;
DR   B0B8F5, SYT_CHLT2  ;  B3QUU7, SYT_CHLT3  ;  Q3KLB6, SYT_CHLTA  ;
DR   B0BA34, SYT_CHLTB  ;  Q8KAN0, SYT_CHLTE  ;  O84585, SYT_CHLTR  ;
DR   Q1QWK7, SYT_CHRSD  ;  Q7NYC6, SYT_CHRVO  ;  Q97GK4, SYT_CLOAB  ;
DR   A7FY87, SYT_CLOB1  ;  C3KTK0, SYT_CLOB6  ;  B2UYW3, SYT_CLOBA  ;
DR   B2TIT5, SYT_CLOBB  ;  A5I6L8, SYT_CLOBH  ;  C1FKN0, SYT_CLOBJ  ;
DR   B1IMV3, SYT_CLOBK  ;  A7GI05, SYT_CLOBL  ;  B1L0T7, SYT_CLOBM  ;
DR   Q189B8, SYT_CLOD6  ;  B9E5W0, SYT_CLOK1  ;  A5N258, SYT_CLOK5  ;
DR   A0PZN1, SYT_CLONN  ;  Q0TMX8, SYT_CLOP1  ;  Q8XI02, SYT_CLOPE  ;
DR   Q0SQM4, SYT_CLOPS  ;  Q891T0, SYT_CLOTE  ;  A3DET1, SYT_CLOTH  ;
DR   Q480A9, SYT_COLP3  ;  C3PGS1, SYT_CORA7  ;  Q6NGW2, SYT_CORDI  ;
DR   Q8FPJ3, SYT_COREF  ;  Q8NPZ0, SYT_CORGL  ;  Q4JVC7, SYT_CORJK  ;
DR   Q83C10, SYT_COXBU  ;  Q0KBZ3, SYT_CUPNH  ;  Q472N7, SYT_CUPPJ  ;
DR   B3R4J1, SYT_CUPTR  ;  Q11UK3, SYT_CYTH3  ;  Q47CM4, SYT_DECAR  ;
DR   Q3Z8G2, SYT_DEHE1  ;  A5FRB3, SYT_DEHSB  ;  Q3ZXB5, SYT_DEHSC  ;
DR   C1D0W2, SYT_DEIDV  ;  Q1IY82, SYT_DEIGD  ;  Q9RSP3, SYT_DEIRA  ;
DR   A9C3D4, SYT_DELAS  ;  B8FN26, SYT_DESAA  ;  C6BRH1, SYT_DESAD  ;
DR   C0QAP1, SYT_DESAH  ;  B8J4E4, SYT_DESDA  ;  Q30Y11, SYT_DESDG  ;
DR   C4XL11, SYT_DESMR  ;  A9A078, SYT_DESOH  ;  A4J4Y7, SYT_DESRM  ;
DR   Q728R5, SYT_DESVH  ;  B8DPN2, SYT_DESVM  ;  A1VBB4, SYT_DESVV  ;
DR   A5EVK6, SYT_DICNV  ;  A8LQX9, SYT_DINSH  ;  A7ZMI6, SYT_ECO24  ;
DR   B7USA2, SYT_ECO27  ;  B7MAS9, SYT_ECO45  ;  B7L6J2, SYT_ECO55  ;
DR   Q8XE27, SYT_ECO57  ;  B5YQ07, SYT_ECO5E  ;  B7NT58, SYT_ECO7I  ;
DR   B7MVJ7, SYT_ECO81  ;  B7M1C7, SYT_ECO8A  ;  C4ZYI1, SYT_ECOBW  ;
DR   B1XGI1, SYT_ECODH  ;  A8A0R2, SYT_ECOHS  ;  A1ABQ2, SYT_ECOK1  ;
DR   Q0THB0, SYT_ECOL5  ;  P0A8M4, SYT_ECOL6  ;  B1IPK9, SYT_ECOLC  ;
DR   P0A8M3, SYT_ECOLI  ;  B7N556, SYT_ECOLU  ;  B6IBD7, SYT_ECOSE  ;
DR   B1LE12, SYT_ECOSM  ;  Q1RB76, SYT_ECOUT  ;  C5B846, SYT_EDWI9  ;
DR   Q3YQP0, SYT_EHRCJ  ;  Q2GI92, SYT_EHRCR  ;  Q5FGP1, SYT_EHRRG  ;
DR   Q5H9Z4, SYT_EHRRW  ;  A4W9M3, SYT_ENT38  ;  Q830D0, SYT_ENTFA  ;
DR   Q6D4G8, SYT_ERWCT  ;  B2VEM1, SYT_ERWT9  ;  Q2N6X5, SYT_ERYLH  ;
DR   B7LQ71, SYT_ESCF3  ;  C4L461, SYT_EXISA  ;  B0S169, SYT_FINM2  ;
DR   A5FP01, SYT_FLAJ1  ;  A6GY22, SYT_FLAPJ  ;  B0TY89, SYT_FRAP2  ;
DR   A8LE67, SYT_FRASN  ;  Q14I20, SYT_FRAT1  ;  A7NDB6, SYT_FRATF  ;
DR   Q2A2J0, SYT_FRATH  ;  B2SGS3, SYT_FRATM  ;  A0Q762, SYT_FRATN  ;
DR   Q0BL41, SYT_FRATO  ;  Q5NGL8, SYT_FRATT  ;  A4IX68, SYT_FRATW  ;
DR   Q8RFS6, SYT_FUSNN  ;  B5EBX9, SYT_GEOBB  ;  Q5KWD2, SYT_GEOKA  ;
DR   Q74D04, SYT_GEOSL  ;  C6DYJ5, SYT_GEOSM  ;  C5D639, SYT_GEOSW  ;
DR   Q7NCU0, SYT_GLOVI  ;  A9HFP5, SYT_GLUDA  ;  Q5FSP9, SYT_GLUOX  ;
DR   Q0BRP0, SYT_GRABC  ;  Q7VKR9, SYT_HAEDU  ;  Q4QK77, SYT_HAEI8  ;
DR   A5UBX5, SYT_HAEIE  ;  A5UEK1, SYT_HAEIG  ;  P43014, SYT_HAEIN  ;
DR   B8F5H9, SYT_HAEPS  ;  Q0I3M2, SYT_HAES1  ;  B0UU42, SYT_HAES2  ;
DR   Q2SDJ2, SYT_HAHCH  ;  A1WU53, SYT_HALHL  ;  Q5UX65, SYT_HALMA  ;
DR   B0R6G6, SYT_HALS3  ;  Q9HP27, SYT_HALSA  ;  Q18H54, SYT_HALWD  ;
DR   C4K776, SYT_HAMD5  ;  Q17VZ5, SYT_HELAH  ;  Q7VJ09, SYT_HELHP  ;
DR   B6JPM2, SYT_HELP2  ;  B5Z9Q1, SYT_HELPG  ;  Q1CV33, SYT_HELPH  ;
DR   Q9ZMV3, SYT_HELPJ  ;  B2URV1, SYT_HELPS  ;  P56071, SYT_HELPY  ;
DR   A4G619, SYT_HERAR  ;  A2BLF3, SYT_HYPBU  ;  Q0BXC2, SYT_HYPNA  ;
DR   Q5QYN4, SYT_IDILO  ;  A6SY30, SYT_JANMA  ;  B5XQC6, SYT_KLEP3  ;
DR   C5CI64, SYT_KOSOT  ;  Q5FIW3, SYT_LACAC  ;  Q03RK3, SYT_LACBA  ;
DR   Q037Z6, SYT_LACC3  ;  B3WF49, SYT_LACCB  ;  Q041U6, SYT_LACGA  ;
DR   A8YWE1, SYT_LACH4  ;  Q74IC0, SYT_LACJO  ;  Q9CED2, SYT_LACLA  ;
DR   A2RN48, SYT_LACLM  ;  Q02WN1, SYT_LACLS  ;  Q88WU9, SYT_LACPL  ;
DR   Q1WUN2, SYT_LACS1  ;  Q38VT0, SYT_LACSS  ;  C1DDA6, SYT_LARHH  ;
DR   Q1MRV8, SYT_LAWIP  ;  Q5X1H3, SYT_LEGPA  ;  A5IAK9, SYT_LEGPC  ;
DR   Q5ZS05, SYT_LEGPH  ;  Q5WT82, SYT_LEGPL  ;  Q6AFC3, SYT_LEIXX  ;
DR   Q04R58, SYT_LEPBJ  ;  Q04ZG7, SYT_LEPBL  ;  B1XYZ3, SYT_LEPCP  ;
DR   Q72PK6, SYT_LEPIC  ;  Q8F6R1, SYT_LEPIN  ;  B1MXZ5, SYT_LEUCK  ;
DR   Q03YF0, SYT_LEUMM  ;  Q92BF5, SYT_LISIN  ;  C1KVK6, SYT_LISMC  ;
DR   Q71ZA9, SYT_LISMF  ;  B8DHI9, SYT_LISMH  ;  Q8Y6X2, SYT_LISMO  ;
DR   A0AJ08, SYT_LISW6  ;  Q2WAI1, SYT_MAGSA  ;  A0L4J6, SYT_MAGSM  ;
DR   Q65TQ0, SYT_MANSM  ;  A1U2C3, SYT_MARAV  ;  Q0AM08, SYT_MARMM  ;
DR   A6VYI1, SYT_MARMS  ;  Q11JM1, SYT_MESSB  ;  A6UW94, SYT_META3  ;
DR   Q8TLX7, SYT_METAC  ;  A7I6P0, SYT_METB6  ;  Q467V2, SYT_METBF  ;
DR   Q12WD4, SYT_METBU  ;  Q60AZ3, SYT_METCA  ;  Q1GZR7, SYT_METFK  ;
DR   Q2FPK3, SYT_METHJ  ;  Q58597, SYT_METJA  ;  Q8TXW5, SYT_METKA  ;
DR   A4FZ87, SYT_METM5  ;  A9A6L7, SYT_METM6  ;  A6VJ50, SYT_METM7  ;
DR   Q8PRY4, SYT_METMA  ;  A3CTJ9, SYT_METMJ  ;  Q6M057, SYT_METMP  ;
DR   B8GHN2, SYT_METPE  ;  A2SH07, SYT_METPP  ;  A5UMJ1, SYT_METS3  ;
DR   A4YH38, SYT_METS5  ;  Q2NE13, SYT_METST  ;  O27504, SYT_METTH  ;
DR   A0B8D4, SYT_METTP  ;  A6US27, SYT_METVS  ;  C5CBI2, SYT_MICLC  ;
DR   A0QID4, SYT_MYCA1  ;  B1MCK6, SYT_MYCA9  ;  P67583, SYT_MYCBO  ;
DR   A1KLW4, SYT_MYCBP  ;  C1AF85, SYT_MYCBT  ;  Q7NBT5, SYT_MYCGA  ;
DR   P47615, SYT_MYCGE  ;  A4TD09, SYT_MYCGI  ;  B8ZUG9, SYT_MYCLB  ;
DR   O07151, SYT_MYCLE  ;  B2HM74, SYT_MYCMM  ;  Q73WE4, SYT_MYCPA  ;
DR   P75225, SYT_MYCPN  ;  Q98PH6, SYT_MYCPU  ;  A0QWG2, SYT_MYCS2  ;
DR   A3PYU0, SYT_MYCSJ  ;  A1UF79, SYT_MYCSK  ;  Q1B9T4, SYT_MYCSS  ;
DR   A5U5W5, SYT_MYCTA  ;  P67582, SYT_MYCTU  ;  A0PSZ4, SYT_MYCUA  ;
DR   A1T868, SYT_MYCVP  ;  Q1D6E3, SYT_MYXXD  ;  Q74MP3, SYT_NANEQ  ;
DR   Q3IRE7, SYT_NATPD  ;  B2A5P2, SYT_NATTJ  ;  B9L5U7, SYT_NAUPA  ;
DR   Q5F9U4, SYT_NEIG1  ;  A9M375, SYT_NEIM0  ;  Q9JVA3, SYT_NEIMA  ;
DR   Q9K095, SYT_NEIMB  ;  Q2GEB1, SYT_NEOSM  ;  Q0ADN4, SYT_NITEC  ;
DR   Q82VV1, SYT_NITEU  ;  A9A2B1, SYT_NITMS  ;  Q2YBS6, SYT_NITMU  ;
DR   Q3JC02, SYT_NITOC  ;  A1SJ90, SYT_NOCSJ  ;  Q2GBX1, SYT_NOVAD  ;
DR   Q8EPF3, SYT_OCEIH  ;  A5CD12, SYT_ORITB  ;  B3CSS5, SYT_ORITI  ;
DR   A6L9S2, SYT_PARD8  ;  A1B0M2, SYT_PARDP  ;  A7HWJ3, SYT_PARL1  ;
DR   Q6M9L0, SYT_PARUW  ;  P57857, SYT_PASMU  ;  C6DFY6, SYT_PECCP  ;
DR   Q03GB7, SYT_PEDPA  ;  Q3A4P3, SYT_PELCD  ;  B4SB93, SYT_PELPB  ;
DR   A1ARE5, SYT_PELPD  ;  Q4FNH9, SYT_PELUB  ;  A9BHF0, SYT_PETMO  ;
DR   B4RE95, SYT_PHEZH  ;  Q7N3P6, SYT_PHOLL  ;  B1V8W6, SYT_PHYAS  ;
DR   B3R0I8, SYT_PHYMT  ;  A1VR77, SYT_POLNA  ;  B1XV14, SYT_POLNS  ;
DR   Q12BR3, SYT_POLSJ  ;  A4SX33, SYT_POLSQ  ;  B2RJD6, SYT_PORG3  ;
DR   Q7MVQ5, SYT_PORGI  ;  B4S3D2, SYT_PROA2  ;  Q6A8U3, SYT_PROAC  ;
DR   A3PBX1, SYT_PROM0  ;  A2C155, SYT_PROM1  ;  A8G3W3, SYT_PROM2  ;
DR   A2CAU4, SYT_PROM3  ;  A9BAX2, SYT_PROM4  ;  A2BVR0, SYT_PROM5  ;
DR   Q31BT7, SYT_PROM9  ;  Q7VBM8, SYT_PROMA  ;  B4ETK6, SYT_PROMH  ;
DR   Q7V8D2, SYT_PROMM  ;  Q7V287, SYT_PROMP  ;  A2BQ78, SYT_PROMS  ;
DR   Q46LV3, SYT_PROMT  ;  A4SCK4, SYT_PROVI  ;  Q48JS3, SYT_PSE14  ;
DR   A6V485, SYT_PSEA7  ;  B7V188, SYT_PSEA8  ;  Q02NP1, SYT_PSEAB  ;
DR   Q9I099, SYT_PSEAE  ;  Q1IC15, SYT_PSEE4  ;  C3JZN7, SYT_PSEFS  ;
DR   A4XTS1, SYT_PSEMY  ;  A5W5E1, SYT_PSEP1  ;  Q3KEY2, SYT_PSEPF  ;
DR   B0KKR8, SYT_PSEPG  ;  Q88K27, SYT_PSEPK  ;  B1J6U4, SYT_PSEPW  ;
DR   Q883H9, SYT_PSESM  ;  P52833, SYT_PSESY  ;  Q4ZUG7, SYT_PSEU2  ;
DR   A4VM22, SYT_PSEU5  ;  Q4FPW3, SYT_PSYA2  ;  Q1Q809, SYT_PSYCK  ;
DR   A1SWU5, SYT_PSYIN  ;  A5WHD5, SYT_PSYWF  ;  Q9UZ14, SYT_PYRAB  ;
DR   Q8ZWK4, SYT_PYRAE  ;  A4WIW5, SYT_PYRAR  ;  A3MTU4, SYT_PYRCJ  ;
DR   Q8U176, SYT_PYRFU  ;  O58430, SYT_PYRHO  ;  A1RV82, SYT_PYRIL  ;
DR   Q5JGC8, SYT_PYRKO  ;  B2UGJ8, SYT_RALPJ  ;  Q8XZ29, SYT_RALSO  ;
DR   B3PNV4, SYT_RHIE6  ;  Q2K859, SYT_RHIEC  ;  Q1MGA7, SYT_RHIL3  ;
DR   Q98LR2, SYT_RHILO  ;  B5ZQK2, SYT_RHILW  ;  Q92QB0, SYT_RHIME  ;
DR   C3MB49, SYT_RHISN  ;  Q7UJ52, SYT_RHOBA  ;  B6IV67, SYT_RHOCS  ;
DR   C0ZZ26, SYT_RHOE4  ;  C1B4B5, SYT_RHOOB  ;  Q6N4D3, SYT_RHOPA  ;
DR   Q2RNL4, SYT_RHORT  ;  A3PLC6, SYT_RHOS1  ;  Q3J0X4, SYT_RHOS4  ;
DR   A4WQU1, SYT_RHOS5  ;  B9KKC7, SYT_RHOSK  ;  Q0S1E2, SYT_RHOSR  ;
DR   C3PMR6, SYT_RICAE  ;  A8GML4, SYT_RICAH  ;  A8GVV1, SYT_RICB8  ;
DR   Q1RJ48, SYT_RICBR  ;  A8EXW5, SYT_RICCK  ;  Q92IX4, SYT_RICCN  ;
DR   Q4UKU3, SYT_RICFE  ;  O05947, SYT_RICPR  ;  C4K0X3, SYT_RICPU  ;
DR   A8GR83, SYT_RICRS  ;  Q68XE8, SYT_RICTY  ;  Q168U9, SYT_ROSDO  ;
DR   Q1AWG4, SYT_RUBXD  ;  A1AWT6, SYT_RUTMC  ;  Q21KE0, SYT_SACD2  ;
DR   B5F7G2, SYT_SALA4  ;  Q57PV3, SYT_SALCH  ;  B5FJA8, SYT_SALDC  ;
DR   B5QVW8, SYT_SALEP  ;  B5RAX3, SYT_SALG2  ;  B4TGH1, SYT_SALHS  ;
DR   B4T4M8, SYT_SALNS  ;  Q5PH96, SYT_SALPA  ;  A9N243, SYT_SALPB  ;
DR   C0Q647, SYT_SALPC  ;  B5BA42, SYT_SALPK  ;  B4TUF0, SYT_SALSV  ;
DR   Q8Z6I2, SYT_SALTI  ;  Q8ZPS9, SYT_SALTY  ;  A8GDQ5, SYT_SERP5  ;
DR   A1S6G4, SYT_SHEAM  ;  B8EES6, SYT_SHEB2  ;  A3D4I2, SYT_SHEB5  ;
DR   A6WNH2, SYT_SHEB8  ;  A9L2Q9, SYT_SHEB9  ;  Q12NI7, SYT_SHEDO  ;
DR   Q082E1, SYT_SHEFN  ;  B0TT20, SYT_SHEHH  ;  A3QEK0, SYT_SHELP  ;
DR   Q8EER9, SYT_SHEON  ;  A8H4U6, SYT_SHEPA  ;  A4Y706, SYT_SHEPC  ;
DR   B8CME8, SYT_SHEPW  ;  A0KWV4, SYT_SHESA  ;  A8FV56, SYT_SHESH  ;
DR   Q0HIT9, SYT_SHESM  ;  Q0HV45, SYT_SHESR  ;  A1RJI3, SYT_SHESW  ;
DR   B1KG61, SYT_SHEWM  ;  B2U397, SYT_SHIB3  ;  Q321L0, SYT_SHIBS  ;
DR   Q32FI0, SYT_SHIDS  ;  Q0T4S9, SYT_SHIF8  ;  P0A8M5, SYT_SHIFL  ;
DR   Q3Z267, SYT_SHISS  ;  Q5LTX8, SYT_SILPO  ;  Q1GFW2, SYT_SILST  ;
DR   A6U8C7, SYT_SINMW  ;  Q2NT31, SYT_SODGM  ;  Q1GVA9, SYT_SPHAL  ;
DR   A7X3A6, SYT_STAA1  ;  A6U2F0, SYT_STAA2  ;  Q2FG54, SYT_STAA3  ;
DR   Q2FXP7, SYT_STAA8  ;  A5ITK7, SYT_STAA9  ;  Q2YTA7, SYT_STAAB  ;
DR   Q5HF90, SYT_STAAC  ;  A6QHL6, SYT_STAAE  ;  P67584, SYT_STAAM  ;
DR   P67585, SYT_STAAN  ;  Q6GG23, SYT_STAAR  ;  Q6G8P3, SYT_STAAS  ;
DR   A8Z2J8, SYT_STAAT  ;  Q8NW68, SYT_STAAW  ;  B9DNC9, SYT_STACT  ;
DR   Q5HNM1, SYT_STAEQ  ;  Q8CS74, SYT_STAES  ;  A3DN67, SYT_STAMF  ;
DR   Q49YB4, SYT_STAS1  ;  Q3K1Z4, SYT_STRA1  ;  Q8E693, SYT_STRA3  ;
DR   Q8E0L9, SYT_STRA5  ;  Q827U8, SYT_STRAW  ;  Q9L278, SYT_STRCO  ;
DR   A8AWB7, SYT_STRGC  ;  B1W3F0, SYT_STRGG  ;  B4SQH4, SYT_STRM5  ;
DR   B2FN79, SYT_STRMK  ;  Q8DT12, SYT_STRMU  ;  Q9A115, SYT_STRP1  ;
DR   Q04JD7, SYT_STRP2  ;  P0DG58, SYT_STRP3  ;  B5E6Q8, SYT_STRP4  ;
DR   Q5XDC4, SYT_STRP6  ;  C1C8M1, SYT_STRP7  ;  Q8P234, SYT_STRP8  ;
DR   Q1JD10, SYT_STRPB  ;  Q1JMY5, SYT_STRPC  ;  Q1JI30, SYT_STRPD  ;
DR   Q1J7X1, SYT_STRPF  ;  A2RFY5, SYT_STRPG  ;  B1I703, SYT_STRPI  ;
DR   B8ZM32, SYT_STRPJ  ;  Q48US7, SYT_STRPM  ;  Q97PI4, SYT_STRPN  ;
DR   P0DG59, SYT_STRPQ  ;  B5XKA6, SYT_STRPZ  ;  Q8DNX8, SYT_STRR6  ;
DR   A4W2F0, SYT_STRS2  ;  C0MCN7, SYT_STRS7  ;  A3CP56, SYT_STRSV  ;
DR   A4VW43, SYT_STRSY  ;  Q5M0T3, SYT_STRT1  ;  Q5M5B9, SYT_STRT2  ;
DR   Q03LP1, SYT_STRTD  ;  B9DU13, SYT_STRU0  ;  C1CFK0, SYT_STRZJ  ;
DR   C1CLX1, SYT_STRZP  ;  C1CSP6, SYT_STRZT  ;  Q4J9C4, SYT_SULAC  ;
DR   C3N1B5, SYT_SULIA  ;  C4KKV9, SYT_SULIK  ;  C3MKT5, SYT_SULIL  ;
DR   C3MUC7, SYT_SULIM  ;  C3NMY1, SYT_SULIN  ;  C3N9B3, SYT_SULIY  ;
DR   A6QD00, SYT_SULNB  ;  Q97VW8, SYT_SULSO  ;  B2V6M2, SYT_SULSY  ;
DR   Q973C8, SYT_SULTO  ;  Q67LA3, SYT_SYMTH  ;  Q31JY3, SYT_SYNE7  ;
DR   Q5N1X6, SYT_SYNP6  ;  A5GJT7, SYT_SYNPW  ;  Q7U662, SYT_SYNPX  ;
DR   Q0I902, SYT_SYNS3  ;  Q3AYC6, SYT_SYNS9  ;  Q3AKU0, SYT_SYNSC  ;
DR   Q0AY05, SYT_SYNWW  ;  Q55806, SYT_SYNY3  ;  C5BSQ1, SYT_TERTT  ;
DR   Q9HL99, SYT_THEAC  ;  Q8DGW0, SYT_THEEB  ;  Q47N28, SYT_THEFY  ;
DR   C5A5J8, SYT_THEGJ  ;  A8F8Q8, SYT_THELT  ;  Q9WZJ9, SYT_THEMA  ;
DR   B9KAN7, SYT_THENN  ;  B1YD09, SYT_THENV  ;  B6YTH4, SYT_THEON  ;
DR   A5IJ45, SYT_THEP1  ;  A1RY76, SYT_THEPD  ;  C6A1R1, SYT_THESM  ;
DR   B1L7W6, SYT_THESQ  ;  Q72HH1, SYT_THET2  ;  P56881, SYT_THET8  ;
DR   Q8R9A4, SYT_THETN  ;  Q978W0, SYT_THEVO  ;  Q31F14, SYT_THICR  ;
DR   Q3SK34, SYT_THIDA  ;  B8GRI1, SYT_THISH  ;  C4LFH3, SYT_TOLAT  ;
DR   Q73NR2, SYT_TREDE  ;  O83809, SYT_TREPA  ;  B2S475, SYT_TREPS  ;
DR   Q83HM3, SYT_TROW8  ;  Q83GK5, SYT_TROWT  ;  Q0W3X9, SYT_UNCMA  ;
DR   B1AJH5, SYT_UREP2  ;  Q9PPV6, SYT_UREPA  ;  B5ZC42, SYT_UREU1  ;
DR   C5CUU2, SYT_VARPS  ;  A1WMG5, SYT_VEREI  ;  A5CWF9, SYT_VESOH  ;
DR   A5EZ18, SYT_VIBC3  ;  Q9KMN7, SYT_VIBCH  ;  C3LUV8, SYT_VIBCM  ;
DR   A7N009, SYT_VIBHB  ;  Q87Q70, SYT_VIBPA  ;  Q8DA13, SYT_VIBVU  ;
DR   Q7MK65, SYT_VIBVY  ;  Q8D3C0, SYT_WIGBR  ;  Q73GH6, SYT_WOLPM  ;
DR   B3CMJ4, SYT_WOLPP  ;  Q5GSG4, SYT_WOLTR  ;  C0R403, SYT_WOLWR  ;
DR   Q8PJE1, SYT_XANAC  ;  Q3BRT7, SYT_XANC5  ;  Q4UW57, SYT_XANC8  ;
DR   B0RRG9, SYT_XANCB  ;  Q8P7Z2, SYT_XANCP  ;  Q2P0Z5, SYT_XANOM  ;
DR   Q5GXY0, SYT_XANOR  ;  B2I9P8, SYT_XYLF2  ;  Q9PFE2, SYT_XYLFA  ;
DR   B0U5E3, SYT_XYLFM  ;  Q87AB2, SYT_XYLFT  ;  A1JMJ9, SYT_YERE8  ;
DR   A7FHG1, SYT_YERP3  ;  Q1C728, SYT_YERPA  ;  B2K668, SYT_YERPB  ;
DR   Q8ZDW5, SYT_YERPE  ;  A9R0A8, SYT_YERPG  ;  Q1CIG3, SYT_YERPN  ;
DR   A4TIL1, SYT_YERPP  ;  Q669Z0, SYT_YERPS  ;  B1JJ17, SYT_YERPY  ;
DR   Q5NPH1, SYT_ZYMMO  ;
//
ID   6.1.1.4
DE   Leucine--tRNA ligase.
AN   Leucine translase.
AN   Leucyl-tRNA synthetase.
CA   ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).
PR   PROSITE; PDOC00161;
DR   A4YE96, SYL1_METS5 ;  Q1MFI6, SYL1_RHIL3 ;  Q4JBP0, SYL1_SULAC ;
DR   P58176, SYL1_SULSO ;  Q974N4, SYL1_SULTO ;  A4YI28, SYL2_METS5 ;
DR   Q1MA25, SYL2_RHIL3 ;  Q4J8J7, SYL2_SULAC ;  O33768, SYL2_SULSO ;
DR   Q970Z6, SYL2_SULTO ;  O66680, SYLA_AQUAE ;  O67646, SYLB_AQUAE ;
DR   Q09996, SYLC_CAEEL ;  Q54N83, SYLC_DICDI ;  Q8SRS8, SYLC_ENCCU ;
DR   B7XHP6, SYLC_ENTBH ;  Q9P2J5, SYLC_HUMAN ;  Q8BMJ2, SYLC_MOUSE ;
DR   P10857, SYLC_NEUCR ;  C4V8L1, SYLC_NOSCE ;  Q5R614, SYLC_PONAB ;
DR   Q10490, SYLC_SCHPO ;  P26637, SYLC_YEAST ;  Q54ET5, SYLM_DICDI ;
DR   Q15031, SYLM_HUMAN ;  Q8VDC0, SYLM_MOUSE ;  P15181, SYLM_NEUCR ;
DR   Q5RDP4, SYLM_PONAB ;  P13503, SYLM_SACDO ;  Q09828, SYLM_SCHPO ;
DR   P11325, SYLM_YEAST ;  B0C1R1, SYL_ACAM1  ;  A9NET8, SYL_ACHLI  ;
DR   A1TVU7, SYL_ACIAC  ;  Q6F817, SYL_ACIAD  ;  B7H051, SYL_ACIB3  ;
DR   B7I5I5, SYL_ACIB5  ;  B2HTC4, SYL_ACIBC  ;  B0VKP9, SYL_ACIBS  ;
DR   B0V5H2, SYL_ACIBY  ;  A0LSY4, SYL_ACIC1  ;  A5G068, SYL_ACICJ  ;
DR   B9MH67, SYL_ACIET  ;  A1WCP8, SYL_ACISJ  ;  A3N0N2, SYL_ACTP2  ;
DR   B3H1L1, SYL_ACTP7  ;  B0BPF7, SYL_ACTPJ  ;  A6VMB8, SYL_ACTSZ  ;
DR   A0KN87, SYL_AERHH  ;  Q9YD97, SYL_AERPE  ;  A4SJW8, SYL_AERS4  ;
DR   Q8UBV2, SYL_AGRT5  ;  B9JV46, SYL_AGRVS  ;  Q0VN53, SYL_ALCBS  ;
DR   Q0ABN3, SYL_ALHEH  ;  B6EIN2, SYL_ALISL  ;  A6TQK3, SYL_ALKMQ  ;
DR   A8MJY6, SYL_ALKOO  ;  B4RX92, SYL_ALTMD  ;  B3ETW5, SYL_AMOA5  ;
DR   Q5PB38, SYL_ANAMM  ;  Q3M3A3, SYL_ANAVT  ;  B7GK53, SYL_ANOFW  ;
DR   A8ERV3, SYL_ARCB4  ;  O30250, SYL_ARCFU  ;  Q5P252, SYL_AROAE  ;
DR   A1R6X5, SYL_ARTAT  ;  A0JX57, SYL_ARTS2  ;  A8IMK0, SYL_AZOC5  ;
DR   B6YRS4, SYL_AZOPC  ;  A1KAH5, SYL_AZOSB  ;  C1DMV9, SYL_AZOVD  ;
DR   A7Z7V7, SYL_BACA2  ;  C3PBK0, SYL_BACAA  ;  C3LAX2, SYL_BACAC  ;
DR   A0RJX2, SYL_BACAH  ;  Q81KK6, SYL_BACAN  ;  B7JT07, SYL_BACC0  ;
DR   Q72YY8, SYL_BACC1  ;  B7IL05, SYL_BACC2  ;  C1EW09, SYL_BACC3  ;
DR   B7H798, SYL_BACC4  ;  B7HSS7, SYL_BACC7  ;  A7GU19, SYL_BACCN  ;
DR   B9J1E1, SYL_BACCQ  ;  Q816T0, SYL_BACCR  ;  Q632V2, SYL_BACCZ  ;
DR   Q5L7B4, SYL_BACFN  ;  Q64MG4, SYL_BACFR  ;  Q9K7S8, SYL_BACHD  ;
DR   Q6HCE2, SYL_BACHK  ;  Q65FX8, SYL_BACLD  ;  A8FGG0, SYL_BACP2  ;
DR   Q5WE05, SYL_BACSK  ;  P36430, SYL_BACSU  ;  Q8A329, SYL_BACTN  ;
DR   A6KZH6, SYL_BACV8  ;  A9VLA2, SYL_BACWK  ;  A1UR39, SYL_BARBK  ;
DR   Q6G1W2, SYL_BARHE  ;  Q6FYL6, SYL_BARQU  ;  A9IYY8, SYL_BART1  ;
DR   Q1LTM9, SYL_BAUCH  ;  Q6MQU3, SYL_BDEBA  ;  A1A1R2, SYL_BIFAA  ;
DR   B3DRD0, SYL_BIFLD  ;  Q8G4D8, SYL_BIFLO  ;  Q7VRA6, SYL_BLOFL  ;
DR   Q492Z3, SYL_BLOPB  ;  Q2KXE5, SYL_BORA1  ;  Q0SNR0, SYL_BORAP  ;
DR   Q7WH33, SYL_BORBR  ;  O51267, SYL_BORBU  ;  B7J1H9, SYL_BORBZ  ;
DR   B5RL76, SYL_BORDL  ;  Q662B4, SYL_BORGA  ;  B2RZW1, SYL_BORHD  ;
DR   Q7W9M4, SYL_BORPA  ;  A9HWW6, SYL_BORPD  ;  Q7VWY7, SYL_BORPE  ;
DR   B5RR67, SYL_BORRA  ;  A1QZ46, SYL_BORT9  ;  C0QWR3, SYL_BRAHW  ;
DR   Q89WQ1, SYL_BRAJA  ;  A5E8H4, SYL_BRASB  ;  A4YJS8, SYL_BRASO  ;
DR   C0ZB13, SYL_BREBN  ;  B2S7N1, SYL_BRUA1  ;  Q2YLH9, SYL_BRUA2  ;
DR   Q57B80, SYL_BRUAB  ;  A9M845, SYL_BRUC2  ;  C0RF58, SYL_BRUMB  ;
DR   Q8YJ44, SYL_BRUME  ;  A5VSE9, SYL_BRUO2  ;  A9WWT1, SYL_BRUSI  ;
DR   Q8FYQ7, SYL_BRUSU  ;  P57519, SYL_BUCAI  ;  Q8K9B9, SYL_BUCAP  ;
DR   P59433, SYL_BUCBP  ;  Q057G3, SYL_BUCCC  ;  B1YTA7, SYL_BURA4  ;
DR   Q1BZ70, SYL_BURCA  ;  B1JVG9, SYL_BURCC  ;  A0K4I0, SYL_BURCH  ;
DR   B4EEW1, SYL_BURCJ  ;  Q0BIB5, SYL_BURCM  ;  A9AHA9, SYL_BURM1  ;
DR   A3MPH9, SYL_BURM7  ;  A2S5J4, SYL_BURM9  ;  Q62H20, SYL_BURMA  ;
DR   A1V0G7, SYL_BURMS  ;  A3NZB6, SYL_BURP0  ;  Q3JNN1, SYL_BURP1  ;
DR   A3NDK5, SYL_BURP6  ;  B2JGX6, SYL_BURP8  ;  Q63QT6, SYL_BURPS  ;
DR   Q39JM5, SYL_BURS3  ;  Q2SZ91, SYL_BURTA  ;  A4JBI1, SYL_BURVG  ;
DR   Q13U82, SYL_BURXL  ;  A4XKG9, SYL_CALS8  ;  A7ZE39, SYL_CAMC1  ;
DR   A7GZ81, SYL_CAMC5  ;  A0RNX3, SYL_CAMFF  ;  A7I0M0, SYL_CAMHC  ;
DR   A8FME4, SYL_CAMJ8  ;  A7H2R6, SYL_CAMJD  ;  Q9PNK3, SYL_CAMJE  ;
DR   A1W078, SYL_CAMJJ  ;  Q5HU13, SYL_CAMJR  ;  B9KCS8, SYL_CAMLR  ;
DR   Q3AF30, SYL_CARHZ  ;  B8GW27, SYL_CAUCN  ;  Q9A217, SYL_CAUCR  ;
DR   B0T6E7, SYL_CAUSK  ;  B3PIB4, SYL_CELJU  ;  Q5L5Q6, SYL_CHLAB  ;
DR   Q3APY5, SYL_CHLCH  ;  Q822R7, SYL_CHLCV  ;  Q254X5, SYL_CHLFF  ;
DR   B3EH05, SYL_CHLL2  ;  Q9PKI4, SYL_CHLMU  ;  B3QM08, SYL_CHLP8  ;
DR   B3EMN5, SYL_CHLPB  ;  A1BDY0, SYL_CHLPD  ;  Q9Z930, SYL_CHLPN  ;
DR   B0B9V9, SYL_CHLT2  ;  B3QRU2, SYL_CHLT3  ;  Q3KMF3, SYL_CHLTA  ;
DR   B0BBI9, SYL_CHLTB  ;  Q8KBY2, SYL_CHLTE  ;  O84211, SYL_CHLTR  ;
DR   Q1QV15, SYL_CHRSD  ;  Q7P0R1, SYL_CHRVO  ;  A8AJG0, SYL_CITK8  ;
DR   A5CR89, SYL_CLAM3  ;  B0RDA6, SYL_CLAMS  ;  Q97LB6, SYL_CLOAB  ;
DR   A7FPP5, SYL_CLOB1  ;  A6M268, SYL_CLOB8  ;  A5HY79, SYL_CLOBH  ;
DR   A7G9T9, SYL_CLOBL  ;  Q182K8, SYL_CLOD6  ;  A5N399, SYL_CLOK5  ;
DR   A0PYK3, SYL_CLONN  ;  Q0TTD0, SYL_CLOP1  ;  Q8XML8, SYL_CLOPE  ;
DR   Q0SV78, SYL_CLOPS  ;  Q898V2, SYL_CLOTE  ;  A3DEU0, SYL_CLOTH  ;
DR   Q484Q5, SYL_COLP3  ;  C3PKU4, SYL_CORA7  ;  Q6NEF5, SYL_CORDI  ;
DR   Q8FLM0, SYL_COREF  ;  A4QI59, SYL_CORGB  ;  Q8NLC4, SYL_CORGL  ;
DR   Q4JSF0, SYL_CORJK  ;  B6J863, SYL_COXB1  ;  B6J1B2, SYL_COXB2  ;
DR   A9KCQ4, SYL_COXBN  ;  A9NC49, SYL_COXBR  ;  Q83DY1, SYL_COXBU  ;
DR   Q46XD8, SYL_CUPPJ  ;  B1WSK6, SYL_CYAA5  ;  B8HM05, SYL_CYAP4  ;
DR   B7KCI7, SYL_CYAP7  ;  B7JYA9, SYL_CYAP8  ;  Q11VK7, SYL_CYTH3  ;
DR   Q47IN0, SYL_DECAR  ;  Q3ZA07, SYL_DEHE1  ;  A5FP73, SYL_DEHSB  ;
DR   Q3ZWQ1, SYL_DEHSC  ;  Q1J0W5, SYL_DEIGD  ;  Q9RSF0, SYL_DEIRA  ;
DR   A9C1G8, SYL_DELAS  ;  B8F9F0, SYL_DESAA  ;  C0QI75, SYL_DESAH  ;
DR   B1I5R7, SYL_DESAP  ;  Q30YL0, SYL_DESDG  ;  B8FUR3, SYL_DESHD  ;
DR   Q24SP5, SYL_DESHY  ;  Q6AJZ7, SYL_DESPS  ;  A4J7H2, SYL_DESRM  ;
DR   Q72CT7, SYL_DESVH  ;  B8DJF0, SYL_DESVM  ;  A1VEL2, SYL_DESVV  ;
DR   A5EWD6, SYL_DICNV  ;  A8LJY0, SYL_DINSH  ;  A7ZJ31, SYL_ECO24  ;
DR   B7UKT2, SYL_ECO27  ;  B7MFR5, SYL_ECO45  ;  B7L9I6, SYL_ECO55  ;
DR   Q8XBN8, SYL_ECO57  ;  B5YQJ4, SYL_ECO5E  ;  B7NM01, SYL_ECO7I  ;
DR   B7MRS9, SYL_ECO81  ;  B7M5G9, SYL_ECO8A  ;  C4ZWC9, SYL_ECOBW  ;
DR   A7ZXR8, SYL_ECOHS  ;  A1A8R7, SYL_ECOK1  ;  Q0TK31, SYL_ECOL5  ;
DR   Q8FJY9, SYL_ECOL6  ;  B1IYG6, SYL_ECOLC  ;  P07813, SYL_ECOLI  ;
DR   B7N9P8, SYL_ECOLU  ;  B6I153, SYL_ECOSE  ;  B1LL91, SYL_ECOSM  ;
DR   Q1RER9, SYL_ECOUT  ;  C5BGC7, SYL_EDWI9  ;  Q3YSH6, SYL_EHRCJ  ;
DR   Q2GG41, SYL_EHRCR  ;  Q5FHG5, SYL_EHRRG  ;  Q5HBM8, SYL_EHRRW  ;
DR   B2KB05, SYL_ELUMP  ;  A4W827, SYL_ENT38  ;  Q837N5, SYL_ENTFA  ;
DR   A7MQS0, SYL_ENTS8  ;  Q6D7L6, SYL_ERWCT  ;  B2VBM4, SYL_ERWT9  ;
DR   B7LLH1, SYL_ESCF3  ;  B1YKH4, SYL_EXIS2  ;  A7HN82, SYL_FERNB  ;
DR   B0S101, SYL_FINM2  ;  A5FMG2, SYL_FLAJ1  ;  A6H244, SYL_FLAPJ  ;
DR   Q0RCJ1, SYL_FRAAA  ;  B0U0E8, SYL_FRAP2  ;  Q2J641, SYL_FRASC  ;
DR   Q14HL6, SYL_FRAT1  ;  A7NCQ3, SYL_FRATF  ;  Q2A307, SYL_FRATH  ;
DR   B2SGM9, SYL_FRATM  ;  A0Q693, SYL_FRATN  ;  Q0BLI7, SYL_FRATO  ;
DR   Q5NG64, SYL_FRATT  ;  A4IXU1, SYL_FRATW  ;  Q8RIQ3, SYL_FUSNN  ;
DR   B5EE39, SYL_GEOBB  ;  Q5KW09, SYL_GEOKA  ;  Q39T99, SYL_GEOMG  ;
DR   B9M9F3, SYL_GEOSF  ;  Q74AZ0, SYL_GEOSL  ;  C6E100, SYL_GEOSM  ;
DR   C5D6D7, SYL_GEOSW  ;  A4IRY3, SYL_GEOTN  ;  A5G677, SYL_GEOUR  ;
DR   Q7NE01, SYL_GLOVI  ;  Q5FTV3, SYL_GLUOX  ;  Q0BW99, SYL_GRABC  ;
DR   A0M5T1, SYL_GRAFK  ;  Q7VM66, SYL_HAEDU  ;  Q4QLY8, SYL_HAEI8  ;
DR   A5UDF4, SYL_HAEIE  ;  A5UI62, SYL_HAEIG  ;  P43827, SYL_HAEIN  ;
DR   Q0I5C5, SYL_HAES1  ;  B0URM9, SYL_HAES2  ;  Q2SBE7, SYL_HAHCH  ;
DR   A1WYZ7, SYL_HALHL  ;  B8CXR8, SYL_HALOH  ;  Q9HN72, SYL_HALSA  ;
DR   C4K7R7, SYL_HAMD5  ;  Q17YZ0, SYL_HELAH  ;  Q7VIY7, SYL_HELHP  ;
DR   B0TBJ3, SYL_HELMI  ;  Q1CR59, SYL_HELPH  ;  Q9ZJ63, SYL_HELPJ  ;
DR   P56457, SYL_HELPY  ;  A9AZ11, SYL_HERA2  ;  A4G8E6, SYL_HERAR  ;
DR   Q0BWB5, SYL_HYPNA  ;  Q5QYD1, SYL_IDILO  ;  A8A8T2, SYL_IGNH4  ;
DR   A6T239, SYL_JANMA  ;  Q28VD4, SYL_JANSC  ;  A6WDL7, SYL_KINRD  ;
DR   B5XZR2, SYL_KLEP3  ;  A6T6A3, SYL_KLEP7  ;  Q5FIP3, SYL_LACAC  ;
DR   Q03RH7, SYL_LACBA  ;  Q03AT8, SYL_LACC3  ;  B3WCD5, SYL_LACCB  ;
DR   Q1G971, SYL_LACDA  ;  Q049B7, SYL_LACDB  ;  B2GDF8, SYL_LACF3  ;
DR   Q045L5, SYL_LACGA  ;  A8YWU4, SYL_LACH4  ;  Q74KS1, SYL_LACJO  ;
DR   Q9CHB6, SYL_LACLA  ;  A2RLY6, SYL_LACLM  ;  Q030E7, SYL_LACLS  ;
DR   Q88XA9, SYL_LACPL  ;  A5VL28, SYL_LACRD  ;  B2G8G2, SYL_LACRJ  ;
DR   Q1WUT3, SYL_LACS1  ;  Q38VP5, SYL_LACSS  ;  C1DA02, SYL_LARHH  ;
DR   Q1MS17, SYL_LAWIP  ;  Q5X5L8, SYL_LEGPA  ;  A5IBJ1, SYL_LEGPC  ;
DR   Q5ZVU2, SYL_LEGPH  ;  Q5WWZ8, SYL_LEGPL  ;  Q6AEW2, SYL_LEIXX  ;
DR   B0SAB8, SYL_LEPBA  ;  Q04Q48, SYL_LEPBJ  ;  Q054T5, SYL_LEPBL  ;
DR   B0STJ3, SYL_LEPBP  ;  B1XXY5, SYL_LEPCP  ;  Q72UY6, SYL_LEPIC  ;
DR   Q8EZY7, SYL_LEPIN  ;  B1MY11, SYL_LEUCK  ;  Q03YH4, SYL_LEUMM  ;
DR   Q92AZ9, SYL_LISIN  ;  C1KVV9, SYL_LISMC  ;  Q71Z07, SYL_LISMF  ;
DR   B8DFR1, SYL_LISMH  ;  Q8Y6M4, SYL_LISMO  ;  A0AJB5, SYL_LISW6  ;
DR   B1HXY7, SYL_LYSSC  ;  B9E7H4, SYL_MACCJ  ;  Q2WBE4, SYL_MAGSA  ;
DR   A0L4R4, SYL_MAGSM  ;  Q65VR5, SYL_MANSM  ;  A1U4A0, SYL_MARAV  ;
DR   Q0AKF5, SYL_MARMM  ;  A6VZE7, SYL_MARMS  ;  Q6F0X5, SYL_MESFL  ;
DR   Q11DE4, SYL_MESSB  ;  A6UTK3, SYL_META3  ;  Q8TQD3, SYL_METAC  ;
DR   Q46AW0, SYL_METBF  ;  Q12WA2, SYL_METBU  ;  Q608N7, SYL_METCA  ;
DR   Q1GZB5, SYL_METFK  ;  Q58050, SYL_METJA  ;  Q8TVM4, SYL_METKA  ;
DR   A4FYA3, SYL_METM5  ;  A6VK04, SYL_METM7  ;  Q8Q054, SYL_METMA  ;
DR   Q6LZD2, SYL_METMP  ;  A2SC91, SYL_METPP  ;  B8EQP4, SYL_METSB  ;
DR   O27552, SYL_METTH  ;  A0B7B7, SYL_METTP  ;  A6USJ5, SYL_METVS  ;
DR   Q2RKZ1, SYL_MOOTA  ;  A0Q8W7, SYL_MYCA1  ;  P67511, SYL_MYCBO  ;
DR   A1KEK9, SYL_MYCBP  ;  C1AJ38, SYL_MYCBT  ;  Q2SRI9, SYL_MYCCT  ;
DR   Q7NB47, SYL_MYCGA  ;  P47508, SYL_MYCGE  ;  A4T4R2, SYL_MYCGI  ;
DR   B8ZTR5, SYL_MYCLB  ;  Q50192, SYL_MYCLE  ;  B2HIA2, SYL_MYCMM  ;
DR   Q6MSR0, SYL_MYCMS  ;  Q744V3, SYL_MYCPA  ;  Q8EW18, SYL_MYCPE  ;
DR   P75398, SYL_MYCPN  ;  Q98RB6, SYL_MYCPU  ;  A0R7H5, SYL_MYCS2  ;
DR   A3Q8Q1, SYL_MYCSJ  ;  A1UPA5, SYL_MYCSK  ;  Q1B0U5, SYL_MYCSS  ;
DR   A5TYB2, SYL_MYCTA  ;  P67510, SYL_MYCTU  ;  A0PKG2, SYL_MYCUA  ;
DR   A1TI06, SYL_MYCVP  ;  P61760, SYL_NANEQ  ;  B2A6C2, SYL_NATTJ  ;
DR   Q5FAJ3, SYL_NEIG1  ;  B4RNT1, SYL_NEIG2  ;  A9M162, SYL_NEIM0  ;
DR   Q9JW39, SYL_NEIMA  ;  Q9JXT2, SYL_NEIMB  ;  A1KS07, SYL_NEIMF  ;
DR   Q2GDQ6, SYL_NEOSM  ;  Q0AG57, SYL_NITEC  ;  Q820M7, SYL_NITEU  ;
DR   Q1QRZ8, SYL_NITHX  ;  Q2YBQ2, SYL_NITMU  ;  Q3J7S8, SYL_NITOC  ;
DR   A6Q512, SYL_NITSB  ;  Q3SWI2, SYL_NITWN  ;  Q5YN65, SYL_NOCFA  ;
DR   A1SHV9, SYL_NOCSJ  ;  B2J7T9, SYL_NOSP7  ;  Q8YS09, SYL_NOSS1  ;
DR   Q2G3C3, SYL_NOVAD  ;  Q8EP12, SYL_OCEIH  ;  A6WXW1, SYL_OCHA4  ;
DR   Q04FL2, SYL_OENOB  ;  B6JAI4, SYL_OLICO  ;  A5CCT4, SYL_ORITB  ;
DR   A6LGA2, SYL_PARD8  ;  A1B5Q5, SYL_PARDP  ;  A7HSL7, SYL_PARL1  ;
DR   Q6MCC8, SYL_PARUW  ;  P57923, SYL_PASMU  ;  C6DBW8, SYL_PECCP  ;
DR   Q03GG4, SYL_PEDPA  ;  Q3A4P8, SYL_PELCD  ;  Q3B2E1, SYL_PELLD  ;
DR   B4SDX3, SYL_PELPB  ;  A1APS3, SYL_PELPD  ;  A5D416, SYL_PELTS  ;
DR   A9BF22, SYL_PETMO  ;  B4RCZ4, SYL_PHEZH  ;  Q7N755, SYL_PHOLL  ;
DR   Q6LN98, SYL_PHOPR  ;  A1VTV4, SYL_POLNA  ;  B1XT72, SYL_POLNS  ;
DR   Q122Q4, SYL_POLSJ  ;  A4SVD9, SYL_POLSQ  ;  B2RIZ3, SYL_PORG3  ;
DR   Q7MW49, SYL_PORGI  ;  B4S5G4, SYL_PROA2  ;  A3PCW8, SYL_PROM0  ;
DR   A2C242, SYL_PROM1  ;  A8G4T7, SYL_PROM2  ;  A2C9U0, SYL_PROM3  ;
DR   A9BAE4, SYL_PROM4  ;  A2BWL7, SYL_PROM5  ;  Q31AX4, SYL_PROM9  ;
DR   Q7VBZ5, SYL_PROMA  ;  B4EV14, SYL_PROMH  ;  Q7TV01, SYL_PROMM  ;
DR   Q7V1I2, SYL_PROMP  ;  A2BR45, SYL_PROMS  ;  Q46L15, SYL_PROMT  ;
DR   A4SG27, SYL_PROVI  ;  Q48DN1, SYL_PSE14  ;  Q15VK0, SYL_PSEA6  ;
DR   A6V0C2, SYL_PSEA7  ;  B7V9C9, SYL_PSEA8  ;  Q02SF5, SYL_PSEAB  ;
DR   Q9HX33, SYL_PSEAE  ;  Q1I4G7, SYL_PSEE4  ;  Q4K5H6, SYL_PSEF5  ;
DR   C3K2L2, SYL_PSEFS  ;  Q3IJ93, SYL_PSEHT  ;  A4XYW8, SYL_PSEMY  ;
DR   A5W9H9, SYL_PSEP1  ;  Q3K6B0, SYL_PSEPF  ;  B0KJW8, SYL_PSEPG  ;
DR   Q88DN1, SYL_PSEPK  ;  B1J150, SYL_PSEPW  ;  Q87VX3, SYL_PSESM  ;
DR   Q4ZN90, SYL_PSEU2  ;  A4VQZ0, SYL_PSEU5  ;  Q4FU71, SYL_PSYA2  ;
DR   Q1QDA4, SYL_PSYCK  ;  A1SU60, SYL_PSYIN  ;  A5WGH9, SYL_PSYWF  ;
DR   Q9V0B9, SYL_PYRAB  ;  Q8ZXT6, SYL_PYRAE  ;  A4WHK6, SYL_PYRAR  ;
DR   A3MU00, SYL_PYRCJ  ;  Q8U2E6, SYL_PYRFU  ;  O58698, SYL_PYRHO  ;
DR   A1RTX9, SYL_PYRIL  ;  Q8NKR7, SYL_PYRKO  ;  Q1LJ30, SYL_RALME  ;
DR   B2UCA1, SYL_RALPJ  ;  Q8XVT3, SYL_RALSO  ;  A9WS85, SYL_RENSM  ;
DR   B3PS46, SYL_RHIE6  ;  Q2K2S7, SYL_RHIEC  ;  Q98EU7, SYL_RHILO  ;
DR   B5ZV40, SYL_RHILW  ;  Q92KW8, SYL_RHIME  ;  C3MB60, SYL_RHISN  ;
DR   Q7UMC0, SYL_RHOBA  ;  B6IU54, SYL_RHOCS  ;  Q220P5, SYL_RHOFD  ;
DR   Q2J364, SYL_RHOP2  ;  Q07UN5, SYL_RHOP5  ;  Q6ND22, SYL_RHOPA  ;
DR   Q21CM7, SYL_RHOPB  ;  Q13E15, SYL_RHOPS  ;  B3Q8A1, SYL_RHOPT  ;
DR   Q2RN70, SYL_RHORT  ;  A3PMN4, SYL_RHOS1  ;  Q3IZL4, SYL_RHOS4  ;
DR   A4WXA5, SYL_RHOS5  ;  B9KMH8, SYL_RHOSK  ;  Q0SAL1, SYL_RHOSR  ;
DR   C3PNE7, SYL_RICAE  ;  A8GNE3, SYL_RICAH  ;  Q1RJS2, SYL_RICBR  ;
DR   A8EZ02, SYL_RICCK  ;  Q92I35, SYL_RICCN  ;  Q4ULS1, SYL_RICFE  ;
DR   A8F1J5, SYL_RICM5  ;  Q9ZDB1, SYL_RICPR  ;  C4K297, SYL_RICPU  ;
DR   B0BXI2, SYL_RICRO  ;  A8GS16, SYL_RICRS  ;  Q68WV8, SYL_RICTY  ;
DR   A7NFJ2, SYL_ROSCS  ;  Q16E06, SYL_ROSDO  ;  A5V1W3, SYL_ROSS1  ;
DR   Q1AR71, SYL_RUBXD  ;  A1AV52, SYL_RUTMC  ;  Q21FG6, SYL_SACD2  ;
DR   A4FR54, SYL_SACEN  ;  B5EZ89, SYL_SALA4  ;  A8LX93, SYL_SALAI  ;
DR   A9MKC8, SYL_SALAR  ;  Q57RS7, SYL_SALCH  ;  B5FMP4, SYL_SALDC  ;
DR   B5QVP9, SYL_SALEP  ;  B5R7Z6, SYL_SALG2  ;  B4TB51, SYL_SALHS  ;
DR   B4SYK7, SYL_SALNS  ;  Q5PM88, SYL_SALPA  ;  A9MUK3, SYL_SALPB  ;
DR   C0PW78, SYL_SALPC  ;  B5BCE6, SYL_SALPK  ;  Q2S415, SYL_SALRD  ;
DR   B4TPX5, SYL_SALSV  ;  Q8Z8H5, SYL_SALTI  ;  A4X9S8, SYL_SALTO  ;
DR   Q8ZQZ6, SYL_SALTY  ;  A8GB21, SYL_SERP5  ;  A1S8S8, SYL_SHEAM  ;
DR   B8E4X7, SYL_SHEB2  ;  A3D7N6, SYL_SHEB5  ;  A6WRJ9, SYL_SHEB8  ;
DR   A9L001, SYL_SHEB9  ;  Q12R39, SYL_SHEDO  ;  Q087K2, SYL_SHEFN  ;
DR   B0TR44, SYL_SHEHH  ;  A3QH47, SYL_SHELP  ;  Q8EHP4, SYL_SHEON  ;
DR   A8H7C2, SYL_SHEPA  ;  A4Y9E9, SYL_SHEPC  ;  A0KTW7, SYL_SHESA  ;
DR   A8FZ10, SYL_SHESH  ;  Q0HLJ0, SYL_SHESM  ;  Q0HXU4, SYL_SHESR  ;
DR   A1RGU5, SYL_SHESW  ;  B1KDW0, SYL_SHEWM  ;  B2TU77, SYL_SHIB3  ;
DR   Q324Q2, SYL_SHIBS  ;  Q32IT9, SYL_SHIDS  ;  Q0T6Q2, SYL_SHIF8  ;
DR   Q83LX5, SYL_SHIFL  ;  Q3Z4F0, SYL_SHISS  ;  Q5LMY0, SYL_SILPO  ;
DR   Q1GKN8, SYL_SILST  ;  A6UEE2, SYL_SINMW  ;  Q2NUU7, SYL_SODGM  ;
DR   Q01U81, SYL_SOLUE  ;  A9EYY7, SYL_SORC5  ;  Q1GNP7, SYL_SPHAL  ;
DR   A5VA89, SYL_SPHWW  ;  A7X3J9, SYL_STAA1  ;  A6U2M4, SYL_STAA2  ;
DR   Q2FFY0, SYL_STAA3  ;  Q2FXH2, SYL_STAA8  ;  A5ITT0, SYL_STAA9  ;
DR   Q2YTH9, SYL_STAAB  ;  Q5HF16, SYL_STAAC  ;  A6QHU1, SYL_STAAE  ;
DR   P67512, SYL_STAAM  ;  P67513, SYL_STAAN  ;  Q6GFU3, SYL_STAAR  ;
DR   Q6G8G9, SYL_STAAS  ;  A8Z4I6, SYL_STAAT  ;  Q8NW17, SYL_STAAW  ;
DR   Q5HNF1, SYL_STAEQ  ;  Q8CNU8, SYL_STAES  ;  Q4L7A3, SYL_STAHJ  ;
DR   A3DKS1, SYL_STAMF  ;  Q49YI8, SYL_STAS1  ;  Q3JYR6, SYL_STRA1  ;
DR   P67514, SYL_STRA3  ;  P67515, SYL_STRA5  ;  Q82C66, SYL_STRAW  ;
DR   Q9RDL5, SYL_STRCO  ;  C0M8N3, SYL_STRE4  ;  B4U0A1, SYL_STREM  ;
DR   A8AZ43, SYL_STRGC  ;  B1VXF6, SYL_STRGG  ;  B4SRE7, SYL_STRM5  ;
DR   B2FPR7, SYL_STRMK  ;  Q8DS85, SYL_STRMU  ;  Q9A1P0, SYL_STRP1  ;
DR   Q04MJ2, SYL_STRP2  ;  P0DG44, SYL_STRP3  ;  B5E6T0, SYL_STRP4  ;
DR   Q5XE35, SYL_STRP6  ;  C1CB31, SYL_STRP7  ;  Q8P2T2, SYL_STRP8  ;
DR   Q1JDV2, SYL_STRPB  ;  Q1JNR2, SYL_STRPC  ;  Q1JIV9, SYL_STRPD  ;
DR   Q1J8Q8, SYL_STRPF  ;  A2RCB2, SYL_STRPG  ;  B1I8Y2, SYL_STRPI  ;
DR   B8ZKS5, SYL_STRPJ  ;  Q48VJ7, SYL_STRPM  ;  Q97SS0, SYL_STRPN  ;
DR   P0DG45, SYL_STRPQ  ;  B2ISI0, SYL_STRPS  ;  B5XJI9, SYL_STRPZ  ;
DR   Q8DRB6, SYL_STRR6  ;  A4W4F3, SYL_STRS2  ;  C0MET9, SYL_STRS7  ;
DR   A3CKP1, SYL_STRSV  ;  A4VY58, SYL_STRSY  ;  Q5M1L6, SYL_STRT1  ;
DR   Q5M657, SYL_STRT2  ;  Q03MJ2, SYL_STRTD  ;  B9DW16, SYL_STRU0  ;
DR   C1CC47, SYL_STRZJ  ;  C1CID7, SYL_STRZP  ;  C1CPD0, SYL_STRZT  ;
DR   Q30Q82, SYL_SULDN  ;  Q67SB4, SYL_SYMTH  ;  Q2LQK5, SYL_SYNAS  ;
DR   Q31LW9, SYL_SYNE7  ;  A0LK15, SYL_SYNFM  ;  Q2JV13, SYL_SYNJA  ;
DR   Q2JHX0, SYL_SYNJB  ;  B1XP90, SYL_SYNP2  ;  Q5N006, SYL_SYNP6  ;
DR   A5GL71, SYL_SYNPW  ;  Q7U6T1, SYL_SYNPX  ;  A5GT82, SYL_SYNR3  ;
DR   Q0IAE0, SYL_SYNS3  ;  Q3AXV7, SYL_SYNS9  ;  Q3AJU8, SYL_SYNSC  ;
DR   Q0AWK4, SYL_SYNWW  ;  P73274, SYL_SYNY3  ;  Q9HK31, SYL_THEAC  ;
DR   Q8DH61, SYL_THEEB  ;  Q47MY0, SYL_THEFY  ;  A8F8B7, SYL_THELT  ;
DR   A6LJM9, SYL_THEM4  ;  Q9WY15, SYL_THEMA  ;  B1YAS9, SYL_THENV  ;
DR   B6YST9, SYL_THEON  ;  A5IKQ3, SYL_THEP1  ;  Q8RCT6, SYL_THETN  ;
DR   Q97AN8, SYL_THEVO  ;  Q31IE8, SYL_THICR  ;  Q3SG58, SYL_THIDA  ;
DR   B8GV13, SYL_THISH  ;  Q73K81, SYL_TREDE  ;  O83595, SYL_TREPA  ;
DR   B2S3H7, SYL_TREPS  ;  Q114V5, SYL_TRIEI  ;  Q83HV5, SYL_TROW8  ;
DR   Q83GC6, SYL_TROWT  ;  B1AJ10, SYL_UREP2  ;  Q9PQC0, SYL_UREPA  ;
DR   B5ZBI3, SYL_UREU1  ;  C5CJ85, SYL_VARPS  ;  A1WGU0, SYL_VEREI  ;
DR   A5CY09, SYL_VESOH  ;  A5F2X0, SYL_VIBC3  ;  Q9KTE6, SYL_VIBCH  ;
DR   Q5E6U8, SYL_VIBF1  ;  B5FBK7, SYL_VIBFM  ;  A7MY86, SYL_VIBHB  ;
DR   Q87RQ0, SYL_VIBPA  ;  B7VKF7, SYL_VIBSL  ;  Q8DFE2, SYL_VIBVU  ;
DR   Q7MN06, SYL_VIBVY  ;  Q8D333, SYL_WIGBR  ;  Q73IT7, SYL_WOLPM  ;
DR   B3CLT1, SYL_WOLPP  ;  Q7M926, SYL_WOLSU  ;  Q5GS31, SYL_WOLTR  ;
DR   C0R573, SYL_WOLWR  ;  Q8PIW4, SYL_XANAC  ;  Q3BRE4, SYL_XANC5  ;
DR   Q4UWK8, SYL_XANC8  ;  B0RR06, SYL_XANCB  ;  Q8P7J1, SYL_XANCP  ;
DR   Q2P0N0, SYL_XANOM  ;  B2SWH2, SYL_XANOP  ;  Q5GXI8, SYL_XANOR  ;
DR   B2I5T5, SYL_XYLF2  ;  Q9PBG8, SYL_XYLFA  ;  B0U376, SYL_XYLFM  ;
DR   Q87C65, SYL_XYLFT  ;  A1JQ25, SYL_YERE8  ;  A7FKW0, SYL_YERP3  ;
DR   Q1C521, SYL_YERPA  ;  B2K886, SYL_YERPB  ;  Q8ZDF8, SYL_YERPE  ;
DR   A9R6Z0, SYL_YERPG  ;  Q1CKQ4, SYL_YERPN  ;  A4TNZ7, SYL_YERPP  ;
DR   Q66DE3, SYL_YERPS  ;  B1JGA5, SYL_YERPY  ;  Q5NMK1, SYL_ZYMMO  ;
//
ID   6.1.1.5
DE   Isoleucine--tRNA ligase.
AN   Isoleucine translase.
AN   Isoleucyl-tRNA synthetase.
CA   ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-
CA   tRNA(Ile).
PR   PROSITE; PDOC00161;
DR   P84178, SY1_PHYPO  ;  Q81WE4, SYI1_BACAN ;  Q732H4, SYI1_BACC1 ;
DR   Q819R4, SYI1_BACCR ;  Q636D1, SYI1_BACCZ ;  Q6HER9, SYI1_BACHK ;
DR   Q62HL4, SYI1_BURMA ;  Q63WI3, SYI1_BURPS ;  Q8ER41, SYI1_OCEIH ;
DR   P18330, SYI1_PSEFL ;  P41972, SYI1_STAAU ;  Q81R75, SYI2_BACAN ;
DR   Q739A1, SYI2_BACC1 ;  Q81E30, SYI2_BACCR ;  Q63BZ8, SYI2_BACCZ ;
DR   Q6HJF2, SYI2_BACHK ;  Q62CD5, SYI2_BURMA ;  Q63KP6, SYI2_BURPS ;
DR   Q8ET99, SYI2_OCEIH ;  Q8L1B1, SYI2_PSEFL ;  P41368, SYI2_STAAU ;
DR   Q21926, SYIC_CAEEL ;  Q54YD4, SYIC_DICDI ;  Q8SQV6, SYIC_ENCCU ;
DR   B7XK16, SYIC_ENTBH ;  P41252, SYIC_HUMAN ;  Q8BU30, SYIC_MOUSE ;
DR   C4V8Q1, SYIC_NOSCE ;  O13651, SYIC_SCHPO ;  P09436, SYIC_YEAST ;
DR   Q5ZKA2, SYIM_CHICK ;  Q94425, SYIM_CIOIN ;  Q54CE4, SYIM_DICDI ;
DR   Q9NSE4, SYIM_HUMAN ;  Q4R646, SYIM_MACFA ;  Q8BIJ6, SYIM_MOUSE ;
DR   Q9USL3, SYIM_SCHPO ;  P48526, SYIM_YEAST ;  B0C872, SYI_ACAM1  ;
DR   A9NG38, SYI_ACHLI  ;  Q6FG02, SYI_ACIAD  ;  A3MYB6, SYI_ACTP2  ;
DR   B3GZN4, SYI_ACTP7  ;  A0KG39, SYI_AERHH  ;  Q9YF67, SYI_AERPE  ;
DR   A4SIX5, SYI_AERS4  ;  Q8UHJ6, SYI_AGRT5  ;  Q0VSE1, SYI_ALCBS  ;
DR   Q0AAD1, SYI_ALHEH  ;  B6EMY6, SYI_ALISL  ;  Q5PAL9, SYI_ANAMM  ;
DR   B9MRZ5, SYI_ANATD  ;  Q27707, SYI_ANTLO  ;  O66651, SYI_AQUAE  ;
DR   P46207, SYI_AQUPY  ;  A8ES62, SYI_ARCB4  ;  O29622, SYI_ARCFU  ;
DR   Q5P221, SYI_AROAE  ;  A1K4R7, SYI_AZOSB  ;  C1DPH5, SYI_AZOVD  ;
DR   C3P665, SYI_BACAA  ;  C3L730, SYI_BACAC  ;  A0RDG3, SYI_BACAH  ;
DR   B7JJY2, SYI_BACC0  ;  B7IUQ5, SYI_BACC2  ;  C1EPQ9, SYI_BACC3  ;
DR   B7H6N1, SYI_BACC4  ;  B7HLM9, SYI_BACC7  ;  A7GRM0, SYI_BACCN  ;
DR   B9IVX2, SYI_BACCQ  ;  Q5LCU8, SYI_BACFN  ;  Q64U07, SYI_BACFR  ;
DR   Q9K9V0, SYI_BACHD  ;  Q65JV7, SYI_BACLD  ;  Q5WFI3, SYI_BACSK  ;
DR   Q45477, SYI_BACSU  ;  Q8A9K9, SYI_BACTN  ;  A9VTD5, SYI_BACWK  ;
DR   Q6G4S5, SYI_BARHE  ;  Q6G0K6, SYI_BARQU  ;  Q1LSS9, SYI_BAUCH  ;
DR   Q6MKX0, SYI_BDEBA  ;  Q8G3I2, SYI_BIFLO  ;  Q7VQL0, SYI_BLOFL  ;
DR   Q493S3, SYI_BLOPB  ;  Q2L2K5, SYI_BORA1  ;  Q0SM18, SYI_BORAP  ;
DR   Q7WKD5, SYI_BORBR  ;  O51773, SYI_BORBU  ;  B7J0S6, SYI_BORBZ  ;
DR   B5RN32, SYI_BORDL  ;  Q65ZU1, SYI_BORGA  ;  B2S1H8, SYI_BORHD  ;
DR   Q7W8Z2, SYI_BORPA  ;  A9IRC2, SYI_BORPD  ;  Q7VXK3, SYI_BORPE  ;
DR   B5RQH0, SYI_BORRA  ;  A1R0Q9, SYI_BORT9  ;  C0R112, SYI_BRAHW  ;
DR   Q89DF8, SYI_BRAJA  ;  C0ZG86, SYI_BREBN  ;  P0C124, SYI_BRUA2  ;
DR   P0C123, SYI_BRUAB  ;  Q8YB57, SYI_BRUME  ;  Q8FX81, SYI_BRUSU  ;
DR   B8D8V0, SYI_BUCA5  ;  P57249, SYI_BUCAI  ;  Q8K9Z2, SYI_BUCAP  ;
DR   B8D754, SYI_BUCAT  ;  Q89AU9, SYI_BUCBP  ;  Q057X9, SYI_BUCCC  ;
DR   B1YVA4, SYI_BURA4  ;  Q1BUA1, SYI_BURCA  ;  B1JXC3, SYI_BURCC  ;
DR   A0K9T5, SYI_BURCH  ;  B4E8Z7, SYI_BURCJ  ;  Q0BCK8, SYI_BURCM  ;
DR   A9AGN6, SYI_BURM1  ;  B2JDY9, SYI_BURP8  ;  B2T6I7, SYI_BURPP  ;
DR   Q39DM8, SYI_BURS3  ;  Q2T0H3, SYI_BURTA  ;  A4JH32, SYI_BURVG  ;
DR   Q13UW2, SYI_BURXL  ;  A4XKR2, SYI_CALS8  ;  A8Z6P6, SYI_CAMC1  ;
DR   A7GX26, SYI_CAMC5  ;  A0RNK3, SYI_CAMFF  ;  A7I1S7, SYI_CAMHC  ;
DR   P41257, SYI_CAMJE  ;  Q5HU41, SYI_CAMJR  ;  B9KD44, SYI_CAMLR  ;
DR   Q3AEP2, SYI_CARHZ  ;  Q9AAA5, SYI_CAUCR  ;  Q5L5L0, SYI_CHLAB  ;
DR   Q822L8, SYI_CHLCV  ;  Q9PL20, SYI_CHLMU  ;  Q9Z972, SYI_CHLPN  ;
DR   B0B9C6, SYI_CHLT2  ;  Q3KN03, SYI_CHLTA  ;  B0BB05, SYI_CHLTB  ;
DR   Q8KFL5, SYI_CHLTE  ;  O84022, SYI_CHLTR  ;  Q1R0B5, SYI_CHRSD  ;
DR   Q7NS57, SYI_CHRVO  ;  A8ALT6, SYI_CITK8  ;  Q97ES0, SYI_CLOAB  ;
DR   A5N3P1, SYI_CLOK5  ;  A0Q3B0, SYI_CLONN  ;  Q8XHE4, SYI_CLOPE  ;
DR   Q899C3, SYI_CLOTE  ;  Q486U0, SYI_COLP3  ;  Q6NGD7, SYI_CORDI  ;
DR   Q8FNV0, SYI_COREF  ;  Q8NNP0, SYI_CORGL  ;  Q4JW85, SYI_CORJK  ;
DR   B6J9J5, SYI_COXB1  ;  B6J1S2, SYI_COXB2  ;  A9KEI8, SYI_COXBN  ;
DR   A9NBM5, SYI_COXBR  ;  Q83EC9, SYI_COXBU  ;  Q0K7A0, SYI_CUPNH  ;
DR   Q46XM7, SYI_CUPPJ  ;  B3R6E8, SYI_CUPTR  ;  B1WVA3, SYI_CYAA5  ;
DR   B8HMX3, SYI_CYAP4  ;  B7KFT1, SYI_CYAP7  ;  B7K5H5, SYI_CYAP8  ;
DR   Q11NV4, SYI_CYTH3  ;  Q47BK5, SYI_DECAR  ;  Q3Z7P5, SYI_DEHE1  ;
DR   Q3ZY20, SYI_DEHSC  ;  Q9RUP8, SYI_DEIRA  ;  C6BV89, SYI_DESAD  ;
DR   B1I4A3, SYI_DESAP  ;  B8J3R3, SYI_DESDA  ;  Q30ZF7, SYI_DESDG  ;
DR   B8FT35, SYI_DESHD  ;  Q24TH1, SYI_DESHY  ;  Q6AK45, SYI_DESPS  ;
DR   A4J2F4, SYI_DESRM  ;  Q72AR5, SYI_DESVH  ;  B8DPD6, SYI_DESVM  ;
DR   A1VCU3, SYI_DESVV  ;  A5EWT0, SYI_DICNV  ;  A7ZHB5, SYI_ECO24  ;
DR   B7UI71, SYI_ECO27  ;  B7MAE6, SYI_ECO45  ;  B7L4E8, SYI_ECO55  ;
DR   Q8XA49, SYI_ECO57  ;  B5YYB8, SYI_ECO5E  ;  B7NHD0, SYI_ECO7I  ;
DR   B7MNN1, SYI_ECO81  ;  B7M0C2, SYI_ECO8A  ;  C4ZPV2, SYI_ECOBW  ;
DR   B1XBF1, SYI_ECODH  ;  A7ZVX4, SYI_ECOHS  ;  A1A774, SYI_ECOK1  ;
DR   Q0TLW5, SYI_ECOL5  ;  Q8FLB7, SYI_ECOL6  ;  B1IRE9, SYI_ECOLC  ;
DR   P00956, SYI_ECOLI  ;  B7N7Q0, SYI_ECOLU  ;  B6HZ21, SYI_ECOSE  ;
DR   B1LFV6, SYI_ECOSM  ;  Q1RGH6, SYI_ECOUT  ;  C5B7M4, SYI_EDWI9  ;
DR   Q3YRX3, SYI_EHRCJ  ;  Q5FH91, SYI_EHRRG  ;  Q5HB43, SYI_EHRRW  ;
DR   P13502, SYI_ENTAE  ;  Q836V1, SYI_ENTFA  ;  A7MIM3, SYI_ENTS8  ;
DR   Q6D0C3, SYI_ERWCT  ;  B2VGR6, SYI_ERWT9  ;  B7LVN2, SYI_ESCF3  ;
DR   B1YIS7, SYI_EXIS2  ;  A7HMY6, SYI_FERNB  ;  Q9XDB4, SYI_FERPE  ;
DR   B0TZQ5, SYI_FRAP2  ;  Q14HT2, SYI_FRAT1  ;  A7NAD2, SYI_FRATF  ;
DR   Q2A4Z4, SYI_FRATH  ;  B2SF88, SYI_FRATM  ;  A0Q529, SYI_FRATN  ;
DR   Q0BNB5, SYI_FRATO  ;  Q5NGD0, SYI_FRATT  ;  A4IYP1, SYI_FRATW  ;
DR   Q8RH47, SYI_FUSNN  ;  Q5L0V9, SYI_GEOKA  ;  Q747X9, SYI_GEOSL  ;
DR   C5D8P2, SYI_GEOSW  ;  A4IM25, SYI_GEOTN  ;  Q7NF75, SYI_GLOVI  ;
DR   Q5FRI6, SYI_GLUOX  ;  Q7VP34, SYI_HAEDU  ;  Q4QLU5, SYI_HAEI8  ;
DR   A5UDA6, SYI_HAEIE  ;  A5UIA3, SYI_HAEIG  ;  P43824, SYI_HAEIN  ;
DR   B8F5E2, SYI_HAEPS  ;  Q0I1V8, SYI_HAES1  ;  B0UV12, SYI_HAES2  ;
DR   Q2S9T9, SYI_HAHCH  ;  A1WY38, SYI_HALHL  ;  Q5UZ84, SYI_HALMA  ;
DR   B8CWL4, SYI_HALOH  ;  Q9HN97, SYI_HALSA  ;  Q18GW3, SYI_HALWD  ;
DR   Q17ZG3, SYI_HELAH  ;  Q7VGX8, SYI_HELHP  ;  B6JNR5, SYI_HELP2  ;
DR   B5Z943, SYI_HELPG  ;  Q1CRK7, SYI_HELPH  ;  Q9ZJJ1, SYI_HELPJ  ;
DR   B2UVG2, SYI_HELPS  ;  P56456, SYI_HELPY  ;  A4G3E6, SYI_HERAR  ;
DR   B4U8K1, SYI_HYDS0  ;  Q5QZS6, SYI_IDILO  ;  A6SW71, SYI_JANMA  ;
DR   B5Y235, SYI_KLEP3  ;  C5CHA1, SYI_KOSOT  ;  Q5FKU5, SYI_LACAC  ;
DR   Q03QI3, SYI_LACBA  ;  Q039Q9, SYI_LACC3  ;  B3WDZ1, SYI_LACCB  ;
DR   Q1GAS8, SYI_LACDA  ;  Q04B65, SYI_LACDB  ;  B2GB86, SYI_LACF3  ;
DR   A8YUP7, SYI_LACH4  ;  Q74JX6, SYI_LACJO  ;  Q9CEH8, SYI_LACLA  ;
DR   Q88V89, SYI_LACPL  ;  B2G6L2, SYI_LACRJ  ;  Q1WTA9, SYI_LACS1  ;
DR   Q38XM0, SYI_LACSS  ;  C1DCX2, SYI_LARHH  ;  Q1MPH2, SYI_LAWIP  ;
DR   Q5X6G6, SYI_LEGPA  ;  A5IFX5, SYI_LEGPC  ;  Q5ZWZ6, SYI_LEGPH  ;
DR   Q5WXX1, SYI_LEGPL  ;  Q6AFZ0, SYI_LEIXX  ;  B0SBW4, SYI_LEPBA  ;
DR   Q04QS6, SYI_LEPBJ  ;  Q053V3, SYI_LEPBL  ;  B0STE5, SYI_LEPBP  ;
DR   Q72PR7, SYI_LEPIC  ;  Q8F6I1, SYI_LEPIN  ;  Q929Z6, SYI_LISIN  ;
DR   C1KWW3, SYI_LISMC  ;  Q71Y01, SYI_LISMF  ;  B8DBR2, SYI_LISMH  ;
DR   Q8Y5N8, SYI_LISMO  ;  A0AKC5, SYI_LISW6  ;  B9EB60, SYI_MACCJ  ;
DR   Q65RQ2, SYI_MANSM  ;  A1TYY9, SYI_MARAV  ;  A6W346, SYI_MARMS  ;
DR   Q6F175, SYI_MESFL  ;  A6UVK2, SYI_META3  ;  Q8TN62, SYI_METAC  ;
DR   A7IAM2, SYI_METB6  ;  Q465G4, SYI_METBF  ;  Q12ZD1, SYI_METBU  ;
DR   Q605M7, SYI_METCA  ;  Q2FPJ4, SYI_METHJ  ;  B3DYQ6, SYI_METI4  ;
DR   Q58357, SYI_METJA  ;  Q8TWY2, SYI_METKA  ;  A2SPV6, SYI_METLZ  ;
DR   Q8PSV9, SYI_METMA  ;  A3CSI6, SYI_METMJ  ;  Q6LX78, SYI_METMP  ;
DR   O27428, SYI_METTH  ;  P26499, SYI_METTM  ;  A0B7P3, SYI_METTP  ;
DR   B0JSP4, SYI_MICAN  ;  Q2RK59, SYI_MOOTA  ;  A5IY09, SYI_MYCAP  ;
DR   Q7VEZ0, SYI_MYCBO  ;  Q7NBG0, SYI_MYCGA  ;  P47587, SYI_MYCGE  ;
DR   Q602B7, SYI_MYCH2  ;  Q4A8Y0, SYI_MYCH7  ;  Q4AAS1, SYI_MYCHJ  ;
DR   Q9X7E5, SYI_MYCLE  ;  Q6KHN7, SYI_MYCMO  ;  Q6MT28, SYI_MYCMS  ;
DR   Q740U6, SYI_MYCPA  ;  Q8EUN9, SYI_MYCPE  ;  P75258, SYI_MYCPN  ;
DR   Q98PQ2, SYI_MYCPU  ;  Q4A5K5, SYI_MYCS5  ;  Q10765, SYI_MYCTU  ;
DR   Q3ITY7, SYI_NATPD  ;  B2A2I8, SYI_NATTJ  ;  B9L8Z9, SYI_NAUPA  ;
DR   Q5FAF5, SYI_NEIG1  ;  B4RPY6, SYI_NEIG2  ;  A9M1J7, SYI_NEIM0  ;
DR   Q9JVY4, SYI_NEIMA  ;  Q9JXY7, SYI_NEIMB  ;  A1KS62, SYI_NEIMF  ;
DR   Q820M6, SYI_NITEU  ;  Q3J8W1, SYI_NITOC  ;  A6Q4I1, SYI_NITSB  ;
DR   Q3SPJ6, SYI_NITWN  ;  Q5YYW9, SYI_NOCFA  ;  B2IZP5, SYI_NOSP7  ;
DR   Q8YXY3, SYI_NOSS1  ;  Q6YR34, SYI_ONYPE  ;  Q6MDY1, SYI_PARUW  ;
DR   Q9CKF7, SYI_PASMU  ;  C6DF04, SYI_PECCP  ;  Q03EY9, SYI_PEDPA  ;
DR   Q3A1R3, SYI_PELCD  ;  Q4FPA9, SYI_PELUB  ;  C0QP76, SYI_PERMH  ;
DR   A9BI29, SYI_PETMO  ;  Q7N8X2, SYI_PHOLL  ;  Q6LUL1, SYI_PHOPR  ;
DR   Q6L206, SYI_PICTO  ;  Q7MUD3, SYI_PORGI  ;  Q6AB89, SYI_PROAC  ;
DR   A3PAV8, SYI_PROM0  ;  A2C071, SYI_PROM1  ;  A8G2P6, SYI_PROM2  ;
DR   A9BDK6, SYI_PROM4  ;  A2BUL8, SYI_PROM5  ;  Q31CU4, SYI_PROM9  ;
DR   Q7VDV0, SYI_PROMA  ;  B4F2T5, SYI_PROMH  ;  Q7TUN3, SYI_PROMM  ;
DR   Q7V352, SYI_PROMP  ;  A2BP36, SYI_PROMS  ;  Q46HD5, SYI_PROMT  ;
DR   Q48NK6, SYI_PSE14  ;  Q15R04, SYI_PSEA6  ;  A6VBU7, SYI_PSEA7  ;
DR   B7V0A3, SYI_PSEA8  ;  Q02GB7, SYI_PSEAB  ;  Q9HVM4, SYI_PSEAE  ;
DR   Q1I4S5, SYI_PSEE4  ;  Q4K5U4, SYI_PSEF5  ;  C3KDX4, SYI_PSEFS  ;
DR   Q3IEA2, SYI_PSEHT  ;  A4XQV5, SYI_PSEMY  ;  A5VY52, SYI_PSEP1  ;
DR   Q3K6L5, SYI_PSEPF  ;  B0KM84, SYI_PSEPG  ;  Q88Q92, SYI_PSEPK  ;
DR   B1JF83, SYI_PSEPW  ;  Q889E4, SYI_PSESM  ;  Q4ZYJ4, SYI_PSEU2  ;
DR   A4VI60, SYI_PSEU5  ;  Q4FUS5, SYI_PSYA2  ;  A1SZP3, SYI_PSYIN  ;
DR   Q9V072, SYI_PYRAB  ;  Q8ZWU4, SYI_PYRAE  ;  P46214, SYI_PYRFU  ;
DR   O58792, SYI_PYRHO  ;  Q5JJ31, SYI_PYRKO  ;  Q1LJB8, SYI_RALME  ;
DR   B2UAQ4, SYI_RALPJ  ;  Q983N4, SYI_RHILO  ;  Q7UNZ2, SYI_RHOBA  ;
DR   Q6N1M8, SYI_RHOPA  ;  C3PP60, SYI_RICAE  ;  A8GPA1, SYI_RICAH  ;
DR   A8GW18, SYI_RICB8  ;  Q1RIY1, SYI_RICBR  ;  A8EY49, SYI_RICCK  ;
DR   Q92H19, SYI_RICCN  ;  Q4UMD8, SYI_RICFE  ;  Q9ZCU4, SYI_RICPR  ;
DR   C4K2T0, SYI_RICPU  ;  Q68WC2, SYI_RICTY  ;  A1AW09, SYI_RUTMC  ;
DR   Q21HK3, SYI_SACD2  ;  Q57TL5, SYI_SALCH  ;  B5R1N6, SYI_SALEP  ;
DR   B5RF43, SYI_SALG2  ;  Q5PDL9, SYI_SALPA  ;  B5BLL0, SYI_SALPK  ;
DR   Q8Z9N2, SYI_SALTI  ;  Q8ZRZ0, SYI_SALTY  ;  A8G9L4, SYI_SERP5  ;
DR   A1S425, SYI_SHEAM  ;  B8EFC7, SYI_SHEB2  ;  A3D1G5, SYI_SHEB5  ;
DR   A6WKD4, SYI_SHEB8  ;  A9L4U7, SYI_SHEB9  ;  B0TJA9, SYI_SHEHH  ;
DR   A3QBX2, SYI_SHELP  ;  Q8EBI4, SYI_SHEON  ;  A8H1H3, SYI_SHEPA  ;
DR   A4Y4A4, SYI_SHEPC  ;  B8CSC1, SYI_SHEPW  ;  A0KZZ1, SYI_SHESA  ;
DR   A8FSI2, SYI_SHESH  ;  Q0HFY9, SYI_SHESM  ;  Q0HS82, SYI_SHESR  ;
DR   A1RMM6, SYI_SHESW  ;  B1KIT5, SYI_SHEWM  ;  B2U245, SYI_SHIB3  ;
DR   Q326J7, SYI_SHIBS  ;  Q32K71, SYI_SHIDS  ;  Q83MH2, SYI_SHIFL  ;
DR   Q3Z5Y4, SYI_SHISS  ;  Q5LNR7, SYI_SILPO  ;  Q2NVY6, SYI_SODGM  ;
DR   A7X1D8, SYI_STAA1  ;  A6U113, SYI_STAA2  ;  Q2FHP4, SYI_STAA3  ;
DR   Q2FZ82, SYI_STAA8  ;  A5IS79, SYI_STAA9  ;  Q2YXH4, SYI_STAAB  ;
DR   Q5HGN8, SYI_STAAC  ;  A6QG93, SYI_STAAE  ;  P67508, SYI_STAAM  ;
DR   P67509, SYI_STAAN  ;  Q6GHP2, SYI_STAAR  ;  Q6GA19, SYI_STAAS  ;
DR   A8Z3N1, SYI_STAAT  ;  Q8NX29, SYI_STAAW  ;  B9DPP7, SYI_STACT  ;
DR   Q846V6, SYI_STAEP  ;  Q5HPZ9, SYI_STAEQ  ;  Q8CSX1, SYI_STAES  ;
DR   Q4L5P4, SYI_STAHJ  ;  Q49WX5, SYI_STAS1  ;  Q3K2N4, SYI_STRA1  ;
DR   Q8E6N1, SYI_STRA3  ;  Q8E177, SYI_STRA5  ;  Q82AC9, SYI_STRAW  ;
DR   Q9S2X5, SYI_STRCO  ;  A8AW24, SYI_STRGC  ;  B4SP18, SYI_STRM5  ;
DR   B2FTJ0, SYI_STRMK  ;  Q8DVD3, SYI_STRMU  ;  Q99YW3, SYI_STRP1  ;
DR   Q04JB0, SYI_STRP2  ;  P0DG42, SYI_STRP3  ;  B5E709, SYI_STRP4  ;
DR   Q5XB14, SYI_STRP6  ;  C1C8P8, SYI_STRP7  ;  Q8P068, SYI_STRP8  ;
DR   B1I721, SYI_STRPI  ;  B8ZM55, SYI_STRPJ  ;  Q48SL8, SYI_STRPM  ;
DR   P0CB61, SYI_STRPN  ;  P0DG43, SYI_STRPQ  ;  B2IRR4, SYI_STRPS  ;
DR   Q8DNW4, SYI_STRR6  ;  A3CLP4, SYI_STRSV  ;  Q5M0C5, SYI_STRT1  ;
DR   Q5M4X2, SYI_STRT2  ;  Q03L88, SYI_STRTD  ;  C1CFN0, SYI_STRZJ  ;
DR   C1CLZ8, SYI_STRZP  ;  C1CSS4, SYI_STRZT  ;  P46215, SYI_SULAC  ;
DR   Q30SH2, SYI_SULDN  ;  C3N5S5, SYI_SULIA  ;  C3MVH6, SYI_SULIM  ;
DR   A6QB84, SYI_SULNB  ;  Q9UXB1, SYI_SULSO  ;  B2V9T1, SYI_SULSY  ;
DR   Q975H9, SYI_SULTO  ;  Q67Q27, SYI_SYMTH  ;  Q5N1G1, SYI_SYNP6  ;
DR   Q7U9G9, SYI_SYNPX  ;  Q0IDA5, SYI_SYNS3  ;  Q0AYC7, SYI_SYNWW  ;
DR   P73505, SYI_SYNY3  ;  C5BQX2, SYI_TERTT  ;  P36422, SYI_TETTH  ;
DR   B7IGT1, SYI_THEAB  ;  Q9HJT4, SYI_THEAC  ;  Q8DGI7, SYI_THEEB  ;
DR   Q47QV9, SYI_THEFY  ;  A8F465, SYI_THELT  ;  A6LK77, SYI_THEM4  ;
DR   P46213, SYI_THEMA  ;  B9K8X3, SYI_THENN  ;  A5IML2, SYI_THEP1  ;
DR   B0K8R7, SYI_THEP3  ;  B0K2W1, SYI_THEPX  ;  Q72JR6, SYI_THET2  ;
DR   P56690, SYI_THET8  ;  Q8R9L3, SYI_THETN  ;  Q97AG7, SYI_THEVO  ;
DR   Q3SHS3, SYI_THIDA  ;  B8GQR1, SYI_THISH  ;  Q73JB2, SYI_TREDE  ;
DR   O83466, SYI_TREPA  ;  B2S348, SYI_TREPS  ;  Q83I16, SYI_TROW8  ;
DR   Q83G52, SYI_TROWT  ;  Q0W720, SYI_UNCMA  ;  Q9PQ79, SYI_UREPA  ;
DR   A5CX61, SYI_VESOH  ;  A5F8Z3, SYI_VIBC3  ;  Q9KU47, SYI_VIBCH  ;
DR   C3LST7, SYI_VIBCM  ;  Q5E7N4, SYI_VIBF1  ;  B5FA60, SYI_VIBFM  ;
DR   A7MTD6, SYI_VIBHB  ;  Q87S90, SYI_VIBPA  ;  B7VJ87, SYI_VIBSL  ;
DR   Q8DES7, SYI_VIBVU  ;  Q7MNM8, SYI_VIBVY  ;  Q8D2R0, SYI_WIGBR  ;
DR   Q73HW7, SYI_WOLPM  ;  Q7MAL0, SYI_WOLSU  ;  Q5GSS3, SYI_WOLTR  ;
DR   Q8PN19, SYI_XANAC  ;  Q3BW42, SYI_XANC5  ;  Q4US40, SYI_XANC8  ;
DR   B0RY28, SYI_XANCB  ;  Q8PBG6, SYI_XANCP  ;  Q2P5B0, SYI_XANOM  ;
DR   Q5H2E1, SYI_XANOR  ;  B2I6V2, SYI_XYLF2  ;  Q9PAS7, SYI_XYLFA  ;
DR   B0U3Q9, SYI_XYLFM  ;  Q87BL5, SYI_XYLFT  ;  A1JJE1, SYI_YERE8  ;
DR   A7FMD7, SYI_YERP3  ;  Q1C0J3, SYI_YERPA  ;  B2K3M6, SYI_YERPB  ;
DR   Q8ZIM0, SYI_YERPE  ;  A9R008, SYI_YERPG  ;  Q1CMV1, SYI_YERPN  ;
DR   A4TQF3, SYI_YERPP  ;  Q66ES4, SYI_YERPS  ;  B1JKZ8, SYI_YERPY  ;
DR   Q5NQQ7, SYI_ZYMMO  ;
//
ID   6.1.1.6
DE   Lysine--tRNA ligase.
AN   Lysine translase.
AN   Lysyl-tRNA synthetase.
CA   ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys).
PR   PROSITE; PDOC00363;
DR   D0LB45, LYSX_GORB4 ;  A0QHC4, LYSX_MYCA1 ;  B1MAX9, LYSX_MYCA9 ;
DR   Q7VEV7, LYSX_MYCBO ;  A1KJ57, LYSX_MYCBP ;  C1ANR3, LYSX_MYCBT ;
DR   A4T9U2, LYSX_MYCGI ;  B8ZRJ4, LYSX_MYCLB ;  Q9CC23, LYSX_MYCLE ;
DR   B2HR11, LYSX_MYCMM ;  Q740J9, LYSX_MYCPA ;  A0QYV1, LYSX_MYCS2 ;
DR   A3Q0V0, LYSX_MYCSJ ;  A1UHB3, LYSX_MYCSK ;  Q1B7P4, LYSX_MYCSS ;
DR   A5U2Z7, LYSX_MYCTA ;  A5WMW1, LYSX_MYCTF ;  C6DS31, LYSX_MYCTK ;
DR   P94974, LYSX_MYCTU ;  A0PP57, LYSX_MYCUA ;  A1TAC7, LYSX_MYCVP ;
DR   Q5Z3P6, LYSX_NOCFA ;  C0ZL89, LYSX_RHOE4 ;  C1B7Z5, LYSX_RHOOB ;
DR   Q0SAA3, LYSX_RHOSR ;  Q8XD57, SYK1_ECO57 ;  P0A8N4, SYK1_ECOL6 ;
DR   P0A8N3, SYK1_ECOLI ;  Q8TTA3, SYK1_METAC ;  Q8PWA0, SYK1_METMA ;
DR   P67608, SYK1_MYCBO ;  Q98QH1, SYK1_MYCPU ;  P67607, SYK1_MYCTU ;
DR   Q8Z3X8, SYK1_SALTI ;  P28354, SYK1_SALTY ;  Q83JU6, SYK1_SHIFL ;
DR   P0A8N6, SYK2_ECO57 ;  Q8FAT5, SYK2_ECOL6 ;  P0A8N5, SYK2_ECOLI ;
DR   Q8TSN5, SYK2_METAC ;  Q8PVP6, SYK2_METMA ;  Q98QG4, SYK2_MYCPU ;
DR   Q8SS56, SYKC_ENCCU ;  A9CS74, SYKC_ENTBH ;  C4V8R9, SYKC_NOSCE ;
DR   Q9UUE6, SYKC_SCHPO ;  P15180, SYKC_YEAST ;  O74858, SYKM_SCHPO ;
DR   P32048, SYKM_YEAST ;  Q43990, SYK_ACIAD  ;  B7GXW0, SYK_ACIB3  ;
DR   B0VSE0, SYK_ACIBS  ;  A3M3D6, SYK_ACIBT  ;  B0V9L5, SYK_ACIBY  ;
DR   A3N0G9, SYK_ACTP2  ;  B3H1E8, SYK_ACTP7  ;  B0BP90, SYK_ACTPJ  ;
DR   A6VPH6, SYK_ACTSZ  ;  A0KNK7, SYK_AERHH  ;  Q9YFT9, SYK_AERPE  ;
DR   A4SJK0, SYK_AERS4  ;  Q8U7H6, SYK_AGRT5  ;  B6EMX2, SYK_ALISL  ;
DR   B8JFW2, SYK_ANAD2  ;  Q2IPX5, SYK_ANADE  ;  B4UGU5, SYK_ANASK  ;
DR   Q3M8C8, SYK_ANAVT  ;  O67258, SYK_AQUAE  ;  Q9ZPI1, SYK_ARATH  ;
DR   A8ESJ5, SYK_ARCB4  ;  O29052, SYK_ARCFU  ;  Q5NY31, SYK_AROAE  ;
DR   Q2NJZ8, SYK_AYWBP  ;  B6YRR7, SYK_AZOPC  ;  A1K5J9, SYK_AZOSB  ;
DR   A0R8E9, SYK_BACAH  ;  Q81VW3, SYK_BACAN  ;  B7JK84, SYK_BACC0  ;
DR   Q73FD1, SYK_BACC1  ;  B7ISY7, SYK_BACC2  ;  B7HJ16, SYK_BACC4  ;
DR   B7HPY8, SYK_BACC7  ;  A7GJY9, SYK_BACCN  ;  Q81J70, SYK_BACCR  ;
DR   Q63HC2, SYK_BACCZ  ;  Q5L9E5, SYK_BACFN  ;  Q64PM9, SYK_BACFR  ;
DR   Q9KGG4, SYK_BACHD  ;  Q6HPU0, SYK_BACHK  ;  Q5WLU5, SYK_BACSK  ;
DR   P37477, SYK_BACSU  ;  Q8A5W4, SYK_BACTN  ;  A6L7P5, SYK_BACV8  ;
DR   A9VN90, SYK_BACWK  ;  Q1LTU4, SYK_BAUCH  ;  Q7VRF5, SYK_BLOFL  ;
DR   Q493E1, SYK_BLOPB  ;  Q937W6, SYK_BORAF  ;  Q7WK46, SYK_BORBR  ;
DR   O51603, SYK_BORBU  ;  Q937U7, SYK_BORGA  ;  Q7W8T6, SYK_BORPA  ;
DR   A9IQY2, SYK_BORPD  ;  Q7VZ37, SYK_BORPE  ;  Q8YCM8, SYK_BRUME  ;
DR   P59225, SYK_BRUSU  ;  P57512, SYK_BUCAI  ;  Q8K9C5, SYK_BUCAP  ;
DR   Q89AC5, SYK_BUCBP  ;  Q057G7, SYK_BUCCC  ;  B1YT20, SYK_BURA4  ;
DR   Q1BHT1, SYK_BURCA  ;  B1JUZ7, SYK_BURCC  ;  A0K8P2, SYK_BURCH  ;
DR   B4EDB2, SYK_BURCJ  ;  Q0BDR2, SYK_BURCM  ;  A9AGV1, SYK_BURM1  ;
DR   A3ML91, SYK_BURM7  ;  A2SAT3, SYK_BURM9  ;  Q62IZ9, SYK_BURMA  ;
DR   A1V5L6, SYK_BURMS  ;  A3NX27, SYK_BURP0  ;  Q3JQP3, SYK_BURP1  ;
DR   A3NB96, SYK_BURP6  ;  B2JIY1, SYK_BURP8  ;  B2SXV7, SYK_BURPP  ;
DR   Q63SN9, SYK_BURPS  ;  Q2SXD6, SYK_BURTA  ;  A4JFZ6, SYK_BURVG  ;
DR   Q13WZ5, SYK_BURXL  ;  Q22099, SYK_CAEEL  ;  A7I3S8, SYK_CAMHC  ;
DR   A8FKI8, SYK_CAMJ8  ;  A7H4X7, SYK_CAMJD  ;  P41258, SYK_CAMJE  ;
DR   A1VYC1, SYK_CAMJJ  ;  Q5HW66, SYK_CAMJR  ;  Q46464, SYK_CAMUP  ;
DR   Q3A9M2, SYK_CARHZ  ;  B8GXH3, SYK_CAUCN  ;  Q9ABY6, SYK_CAUCR  ;
DR   B0T2A6, SYK_CAUSK  ;  P0CW89, SYK_CENSM  ;  P0CW90, SYK_CENSY  ;
DR   A9WK04, SYK_CHLAA  ;  Q5L545, SYK_CHLAB  ;  Q3ARD7, SYK_CHLCH  ;
DR   Q821U6, SYK_CHLCV  ;  Q255U2, SYK_CHLFF  ;  Q9PLE1, SYK_CHLMU  ;
DR   B3QMN9, SYK_CHLP8  ;  Q9Z6X5, SYK_CHLPN  ;  B0B907, SYK_CHLT2  ;
DR   Q3KKR1, SYK_CHLTA  ;  B0BAN6, SYK_CHLTB  ;  Q8KCM7, SYK_CHLTE  ;
DR   O84786, SYK_CHLTR  ;  Q1QT66, SYK_CHRSD  ;  Q7NZ62, SYK_CHRVO  ;
DR   A8AP96, SYK_CITK8  ;  Q97EB7, SYK_CLOAB  ;  A7FZA5, SYK_CLOB1  ;
DR   A5I7P4, SYK_CLOBH  ;  B1IGJ2, SYK_CLOBK  ;  A7GJB3, SYK_CLOBL  ;
DR   B1KTC1, SYK_CLOBM  ;  A5N4L1, SYK_CLOK5  ;  A0PXN4, SYK_CLONN  ;
DR   Q0TMI7, SYK_CLOP1  ;  Q8XHL8, SYK_CLOPE  ;  Q0SQ86, SYK_CLOPS  ;
DR   Q899G7, SYK_CLOTE  ;  Q47WT5, SYK_COLP3  ;  B6J8K2, SYK_COXB1  ;
DR   B6J1P6, SYK_COXB2  ;  A9KEG1, SYK_COXBN  ;  A9NBP7, SYK_COXBR  ;
DR   Q83E97, SYK_COXBU  ;  P37879, SYK_CRIGR  ;  Q0KCG3, SYK_CUPNH  ;
DR   Q473I5, SYK_CUPPJ  ;  B3R478, SYK_CUPTR  ;  Q47C53, SYK_DECAR  ;
DR   Q3Z8X9, SYK_DEHE1  ;  A5FRN5, SYK_DEHSB  ;  Q3ZWX9, SYK_DEHSC  ;
DR   Q9RXE1, SYK_DEIRA  ;  A5EY50, SYK_DICNV  ;  C5BAR6, SYK_EDWI9  ;
DR   A4WE42, SYK_ENT38  ;  Q839A8, SYK_ENTFA  ;  A7MR65, SYK_ENTS8  ;
DR   Q6D945, SYK_ERWCT  ;  B2VF45, SYK_ERWT9  ;  A7HM68, SYK_FERNB  ;
DR   Q8RG52, SYK_FUSNN  ;  Q9RHV9, SYK_GEOSE  ;  Q7NG18, SYK_GLOVI  ;
DR   A0M5H8, SYK_GRAFK  ;  Q7VLU5, SYK_HAEDU  ;  Q4QL88, SYK_HAEI8  ;
DR   A5UCQ0, SYK_HAEIE  ;  A5UIX4, SYK_HAEIG  ;  P43825, SYK_HAEIN  ;
DR   B0URW9, SYK_HAES2  ;  Q2SL47, SYK_HAHCH  ;  Q5UXX4, SYK_HALMA  ;
DR   Q9HNN7, SYK_HALSA  ;  Q17YS1, SYK_HELAH  ;  Q7VFL0, SYK_HELHP  ;
DR   B6JPT1, SYK_HELP2  ;  B5Z9V6, SYK_HELPG  ;  Q1CUX6, SYK_HELPH  ;
DR   Q9ZMP8, SYK_HELPJ  ;  B2US13, SYK_HELPS  ;  P56126, SYK_HELPY  ;
DR   A9B5T5, SYK_HERA2  ;  A4G778, SYK_HERAR  ;  Q15046, SYK_HUMAN  ;
DR   Q5QYV9, SYK_IDILO  ;  A6SXF3, SYK_JANMA  ;  A6W5H6, SYK_KINRD  ;
DR   B2GA78, SYK_LACF3  ;  Q9CII7, SYK_LACLA  ;  A2RIA0, SYK_LACLM  ;
DR   Q031U8, SYK_LACLS  ;  Q88Z28, SYK_LACPL  ;  Q38V83, SYK_LACSS  ;
DR   C1DB68, SYK_LARHH  ;  Q5X4D5, SYK_LEGPA  ;  A5ICT2, SYK_LEGPC  ;
DR   Q5ZUL6, SYK_LEGPH  ;  Q5WVS0, SYK_LEGPL  ;  Q04SM4, SYK_LEPBJ  ;
DR   Q050Q1, SYK_LEPBL  ;  Q72R38, SYK_LEPIC  ;  Q8F4P5, SYK_LEPIN  ;
DR   B1MVJ0, SYK_LEUCK  ;  Q03Z44, SYK_LEUMM  ;  Q92F47, SYK_LISIN  ;
DR   Q724I4, SYK_LISMF  ;  Q8YAB8, SYK_LISMO  ;  A0AF28, SYK_LISW6  ;
DR   B1HSY5, SYK_LYSSC  ;  A0L6F7, SYK_MAGSM  ;  Q65SB0, SYK_MANSM  ;
DR   Q9C4B7, SYK_METBA  ;  Q46CD2, SYK_METBF  ;  Q1H372, SYK_METFK  ;
DR   Q2FSN8, SYK_METHJ  ;  Q57959, SYK_METJA  ;  Q8TWP6, SYK_METKA  ;
DR   P0CW66, SYK_METMI  ;  A3CY14, SYK_METMJ  ;  P0CW67, SYK_METMP  ;
DR   A2SDC3, SYK_METPP  ;  Q2NHG8, SYK_METST  ;  O27585, SYK_METTH  ;
DR   Q2RM49, SYK_MOOTA  ;  Q99MN1, SYK_MOUSE  ;  B3PNH7, SYK_MYCA5  ;
DR   A1KPT4, SYK_MYCBP  ;  C1AI57, SYK_MYCBT  ;  Q2SR35, SYK_MYCCT  ;
DR   Q49158, SYK_MYCFE  ;  Q7NC34, SYK_MYCGA  ;  P47382, SYK_MYCGE  ;
DR   A4T5M9, SYK_MYCGI  ;  Q4A8F8, SYK_MYCH7  ;  Q4AAC7, SYK_MYCHJ  ;
DR   P46191, SYK_MYCHP  ;  P46861, SYK_MYCLE  ;  Q6KIP6, SYK_MYCMO  ;
DR   Q6MUG2, SYK_MYCMS  ;  Q8EUS8, SYK_MYCPE  ;  P75500, SYK_MYCPN  ;
DR   Q4A5F3, SYK_MYCS5  ;  A5U8S4, SYK_MYCTA  ;  Q3IRL7, SYK_NATPD  ;
DR   Q5F6U2, SYK_NEIG1  ;  B4RP57, SYK_NEIG2  ;  Q9JTT7, SYK_NEIMA  ;
DR   Q9JYU6, SYK_NEIMB  ;  A1KUN1, SYK_NEIMF  ;  Q82SH1, SYK_NITEU  ;
DR   B2J384, SYK_NOSP7  ;  Q8YPW9, SYK_NOSS1  ;  Q8EU10, SYK_OCEIH  ;
DR   Q6YPY6, SYK_ONYPE  ;  Q6F2U9, SYK_ORYSJ  ;  A6L8C6, SYK_PARD8  ;
DR   P57822, SYK_PASMU  ;  C6D8Z6, SYK_PECCP  ;  Q03E09, SYK_PEDPA  ;
DR   Q3B365, SYK_PELLD  ;  B4SB22, SYK_PELPB  ;  A5D5Q4, SYK_PELTS  ;
DR   Q7N1C8, SYK_PHOLL  ;  Q6LUN2, SYK_PHOPR  ;  B1VA97, SYK_PHYAS  ;
DR   Q6L1V1, SYK_PICTO  ;  B1XTS4, SYK_POLNS  ;  A4SYX2, SYK_POLSQ  ;
DR   B2RJY1, SYK_PORG3  ;  Q7MUV7, SYK_PORGI  ;  A3PFA8, SYK_PROM0  ;
DR   A8G7C4, SYK_PROM2  ;  A2C629, SYK_PROM3  ;  A9BD62, SYK_PROM4  ;
DR   A2BZ03, SYK_PROM5  ;  Q318C3, SYK_PROM9  ;  Q7V9Q0, SYK_PROMA  ;
DR   B4F0M6, SYK_PROMH  ;  Q7U3A4, SYK_PROMM  ;  Q7UZP0, SYK_PROMP  ;
DR   Q48F26, SYK_PSE14  ;  A6V187, SYK_PSEA7  ;  B7V0Z5, SYK_PSEA8  ;
DR   Q02RH2, SYK_PSEAB  ;  Q9HXU0, SYK_PSEAE  ;  Q1IDW1, SYK_PSEE4  ;
DR   Q4KHL4, SYK_PSEF5  ;  A4XXQ6, SYK_PSEMY  ;  A5W890, SYK_PSEP1  ;
DR   Q3KHF3, SYK_PSEPF  ;  B0KRL5, SYK_PSEPG  ;  Q88MS3, SYK_PSEPK  ;
DR   B1JD39, SYK_PSEPW  ;  Q886S6, SYK_PSESM  ;  Q4ZWW0, SYK_PSEU2  ;
DR   Q4FSV2, SYK_PSYA2  ;  Q1QAW5, SYK_PSYCK  ;  A1T047, SYK_PSYIN  ;
DR   A5WFG0, SYK_PSYWF  ;  Q9V270, SYK_PYRAB  ;  Q8U4F3, SYK_PYRFU  ;
DR   O57963, SYK_PYRHO  ;  Q5JHQ3, SYK_PYRKO  ;  Q1LPK6, SYK_RALME  ;
DR   B2U8U9, SYK_RALPJ  ;  Q8Y0L5, SYK_RALSO  ;  B3Q0S4, SYK_RHIE6  ;
DR   Q2K424, SYK_RHIEC  ;  Q1MBK9, SYK_RHIL3  ;  Q98BC8, SYK_RHILO  ;
DR   B5ZQW5, SYK_RHILW  ;  O87821, SYK_RHIME  ;  C3PN86, SYK_RICAE  ;
DR   A8GN71, SYK_RICAH  ;  A8GVK6, SYK_RICB8  ;  Q1RI62, SYK_RICBR  ;
DR   A8EZ69, SYK_RICCK  ;  Q92IB5, SYK_RICCN  ;  Q4ULZ0, SYK_RICFE  ;
DR   A8F1D8, SYK_RICM5  ;  Q9ZDF8, SYK_RICPR  ;  C4K2E4, SYK_RICPU  ;
DR   B0BX92, SYK_RICRO  ;  A8GRT7, SYK_RICRS  ;  Q68X04, SYK_RICTY  ;
DR   A7NFC6, SYK_ROSCS  ;  Q16AV0, SYK_ROSDO  ;  A5UPG6, SYK_ROSS1  ;
DR   A1AWN8, SYK_RUTMC  ;  B5F5G4, SYK_SALA4  ;  A9MRI4, SYK_SALAR  ;
DR   Q57K76, SYK_SALCH  ;  B5FUF3, SYK_SALDC  ;  B5QXG7, SYK_SALEP  ;
DR   B5RE01, SYK_SALG2  ;  B4TGW0, SYK_SALHS  ;  B4T535, SYK_SALNS  ;
DR   Q5PL30, SYK_SALPA  ;  A9N3L6, SYK_SALPB  ;  C0PY12, SYK_SALPC  ;
DR   B5BFK5, SYK_SALPK  ;  B4TUQ8, SYK_SALSV  ;  A8GIP4, SYK_SERP5  ;
DR   A1S9M3, SYK_SHEAM  ;  A3D0Y5, SYK_SHEB5  ;  A6WS29, SYK_SHEB8  ;
DR   A9L1I0, SYK_SHEB9  ;  Q12JH2, SYK_SHEDO  ;  Q087X1, SYK_SHEFN  ;
DR   B0TTP2, SYK_SHEHH  ;  A3QB36, SYK_SHELP  ;  Q8EI58, SYK_SHEON  ;
DR   A8H0J7, SYK_SHEPA  ;  A4Y9X9, SYK_SHEPC  ;  B8CU98, SYK_SHEPW  ;
DR   A0L0F1, SYK_SHESA  ;  A8FRH9, SYK_SHESH  ;  Q0HM10, SYK_SHESM  ;
DR   Q0HRS5, SYK_SHESR  ;  A1RGF1, SYK_SHESW  ;  B1KFR7, SYK_SHEWM  ;
DR   B2U0Q7, SYK_SHIB3  ;  Q31WF2, SYK_SHIBS  ;  Q32BV3, SYK_SHIDS  ;
DR   Q0T106, SYK_SHIF8  ;  A6UDA0, SYK_SINMW  ;  Q2NRG1, SYK_SODGM  ;
DR   Q43776, SYK_SOLLC  ;  A7WYS8, SYK_STAA1  ;  Q2FJC3, SYK_STAA3  ;
DR   Q2G0Q3, SYK_STAA8  ;  Q2YVW8, SYK_STAAB  ;  Q5HIF7, SYK_STAAC  ;
DR   P67609, SYK_STAAM  ;  P67610, SYK_STAAN  ;  Q6GJF4, SYK_STAAR  ;
DR   Q6GBX1, SYK_STAAS  ;  Q53638, SYK_STAAU  ;  Q8NXZ0, SYK_STAAW  ;
DR   Q5HRN7, SYK_STAEQ  ;  Q8CQV5, SYK_STAES  ;  Q4L3H5, SYK_STAHJ  ;
DR   Q49V26, SYK_STAS1  ;  Q3K1V5, SYK_STRA1  ;  Q8E656, SYK_STRA3  ;
DR   Q8E0I1, SYK_STRA5  ;  Q9X895, SYK_STRCO  ;  A8AW92, SYK_STRGC  ;
DR   Q8DUW8, SYK_STRMU  ;  Q9A0V7, SYK_STRP1  ;  Q04LI2, SYK_STRP2  ;
DR   P0DG46, SYK_STRP3  ;  B5E317, SYK_STRP4  ;  Q5XD62, SYK_STRP6  ;
DR   Q8P1X6, SYK_STRP8  ;  A2RFR7, SYK_STRPG  ;  B1IAN6, SYK_STRPI  ;
DR   Q97RS9, SYK_STRPN  ;  P0DG47, SYK_STRPQ  ;  B2IN95, SYK_STRPS  ;
DR   B5XKG9, SYK_STRPZ  ;  Q8CWS5, SYK_STRR6  ;  A4VZY0, SYK_STRS2  ;
DR   A3CP17, SYK_STRSV  ;  A4VTP6, SYK_STRSY  ;  Q03LD3, SYK_STRTD  ;
DR   Q4JCI5, SYK_SULAC  ;  P95970, SYK_SULSO  ;  Q31KH4, SYK_SYNE7  ;
DR   Q5N1D9, SYK_SYNP6  ;  A5GI38, SYK_SYNPW  ;  Q7U9X5, SYK_SYNPX  ;
DR   A5GQ58, SYK_SYNR3  ;  Q0IDW9, SYK_SYNS3  ;  Q3B0J9, SYK_SYNS9  ;
DR   Q3ANE6, SYK_SYNSC  ;  Q0B0N3, SYK_SYNWW  ;  P73443, SYK_SYNY3  ;
DR   C5BRM0, SYK_TERTT  ;  B7ID87, SYK_THEAB  ;  P57677, SYK_THEAC  ;
DR   Q8DMA9, SYK_THEEB  ;  A8F4K1, SYK_THELT  ;  A6LMS4, SYK_THEM4  ;
DR   Q9X231, SYK_THEMA  ;  A5ILE6, SYK_THEP1  ;  B0KCE4, SYK_THEP3  ;
DR   B0K5C0, SYK_THEPX  ;  B1LAX6, SYK_THESQ  ;  Q72JT9, SYK_THET2  ;
DR   Q5SJG7, SYK_THET8  ;  P41255, SYK_THETH  ;  Q8R7N1, SYK_THETN  ;
DR   Q979B8, SYK_THEVO  ;  Q3SKD9, SYK_THIDA  ;  B8GRJ2, SYK_THISH  ;
DR   C4LCP0, SYK_TOLAT  ;  O83650, SYK_TREPA  ;  B1AI47, SYK_UREP2  ;
DR   Q9PR83, SYK_UREPA  ;  B5ZAP2, SYK_UREU1  ;  C5CSG3, SYK_VARPS  ;
DR   A5CWL4, SYK_VESOH  ;  Q9KU60, SYK_VIBCH  ;  Q5E7P8, SYK_VIBF1  ;
DR   B5F9U5, SYK_VIBFM  ;  A7MXL2, SYK_VIBHB  ;  Q87SB1, SYK_VIBPA  ;
DR   Q8DEQ9, SYK_VIBVU  ;  Q7MNP6, SYK_VIBVY  ;  Q8D2B3, SYK_WIGBR  ;
DR   Q7MAR1, SYK_WOLSU  ;  Q8PLC6, SYK_XANAC  ;  Q3BUB6, SYK_XANC5  ;
DR   Q4UU84, SYK_XANC8  ;  B0RSQ8, SYK_XANCB  ;  Q9L3G6, SYK_XANCP  ;
DR   Q2P1U6, SYK_XANOM  ;  B2SV97, SYK_XANOP  ;  B2I848, SYK_XYLF2  ;
DR   Q9PEB6, SYK_XYLFA  ;  B0U572, SYK_XYLFM  ;  Q87EB3, SYK_XYLFT  ;
DR   A1JPL4, SYK_YERE8  ;  A7FF39, SYK_YERP3  ;  Q1CB23, SYK_YERPA  ;
DR   B2K0N6, SYK_YERPB  ;  Q8ZHK5, SYK_YERPE  ;  A9R4M4, SYK_YERPG  ;
DR   Q1CF16, SYK_YERPN  ;  A4TIC5, SYK_YERPP  ;  Q666T3, SYK_YERPS  ;
DR   B1JPH6, SYK_YERPY  ;
//
ID   6.1.1.7
DE   Alanine--tRNA ligase.
AN   Alanine translase.
AN   Alanyl-tRNA synthetase.
CA   ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).
PR   PROSITE; PDOC00363;
DR   A9KMW7, SYA1_CLOPH ;  A9KLZ5, SYA2_CLOPH ;  P21894, SYAC_BOMMO ;
DR   O01541, SYAC_CAEEL ;  Q54Y20, SYAC_DICDI ;  Q9VLM8, SYAC_DROME ;
DR   P49588, SYAC_HUMAN ;  Q8CFX8, SYAC_MESAU ;  Q8BGQ7, SYAC_MOUSE ;
DR   Q5RC02, SYAC_PONAB ;  P50475, SYAC_RAT   ;  Q23122, SYAM_CAEEL ;
DR   Q86H43, SYAM_DICDI ;  Q9VRJ1, SYAM_DROME ;  Q5JTZ9, SYAM_HUMAN ;
DR   Q14CH7, SYAM_MOUSE ;  D3ZX08, SYAM_RAT   ;  Q9FFC7, SYAP_ARATH ;
DR   C1MR42, SYAP_MICPC ;  B8B4H5, SYAP_ORYSI ;  B9FSH5, SYAP_ORYSJ ;
DR   A4S051, SYAP_OSTLU ;  Q015G2, SYAP_OSTTA ;  B9HQZ6, SYAP_POPTR ;
DR   C5Z7K4, SYAP_SORBI ;  B0CFX4, SYA_ACAM1  ;  A9NGN9, SYA_ACHLI  ;
DR   A1TRL4, SYA_ACIAC  ;  Q6FCT2, SYA_ACIAD  ;  B2HWK7, SYA_ACIBC  ;
DR   Q1IJG7, SYA_ACIBL  ;  A3M3W2, SYA_ACIBT  ;  B0VAI3, SYA_ACIBY  ;
DR   A0LUJ2, SYA_ACIC1  ;  A5FXC2, SYA_ACICJ  ;  A1W7D0, SYA_ACISJ  ;
DR   A3N018, SYA_ACTP2  ;  B3H177, SYA_ACTP7  ;  B0BNS8, SYA_ACTPJ  ;
DR   A6VKD6, SYA_ACTSZ  ;  A0KPG1, SYA_AERHH  ;  Q9Y9X3, SYA_AERPE  ;
DR   A4SS99, SYA_AERS4  ;  Q8UE87, SYA_AGRT5  ;  B2UKT4, SYA_AKKM8  ;
DR   Q0VNK2, SYA_ALCBS  ;  Q0A8K7, SYA_ALHEH  ;  A6TQZ4, SYA_ALKMQ  ;
DR   A8MGI3, SYA_ALKOO  ;  Q2IG40, SYA_ANADE  ;  A7HH87, SYA_ANADF  ;
DR   Q5PBJ0, SYA_ANAMM  ;  Q2GJ36, SYA_ANAPZ  ;  Q3MGN4, SYA_ANAVT  ;
DR   O67323, SYA_AQUAE  ;  Q9XDM3, SYA_AQUPY  ;  P36428, SYA_ARATH  ;
DR   A8EWI6, SYA_ARCB4  ;  O28029, SYA_ARCFU  ;  Q5P7Q3, SYA_AROAE  ;
DR   A1R709, SYA_ARTAT  ;  A0JX88, SYA_ARTS2  ;  Q2NJ60, SYA_AYWBP  ;
DR   A8ICW8, SYA_AZOC5  ;  A1K991, SYA_AZOSB  ;  A7Z735, SYA_BACA2  ;
DR   A0RJ00, SYA_BACAH  ;  Q81LK0, SYA_BACAN  ;  P61697, SYA_BACC1  ;
DR   A7GT67, SYA_BACCN  ;  Q817Z0, SYA_BACCR  ;  Q634F6, SYA_BACCZ  ;
DR   Q5LHE6, SYA_BACFN  ;  Q64YB4, SYA_BACFR  ;  Q9KDE6, SYA_BACHD  ;
DR   Q6HDD7, SYA_BACHK  ;  Q65GS5, SYA_BACLD  ;  A8FFM9, SYA_BACP2  ;
DR   Q5WHM8, SYA_BACSK  ;  O34526, SYA_BACSU  ;  Q8A0M6, SYA_BACTN  ;
DR   A6L1L8, SYA_BACV8  ;  A9VI09, SYA_BACWK  ;  P70865, SYA_BARBA  ;
DR   A1USS4, SYA_BARBK  ;  Q6G2Z4, SYA_BARHE  ;  Q6FZF1, SYA_BARQU  ;
DR   A9IVY8, SYA_BART1  ;  Q1LTQ4, SYA_BAUCH  ;  P61698, SYA_BDEBA  ;
DR   B2IHX3, SYA_BEII9  ;  A1A198, SYA_BIFAA  ;  Q8G5W9, SYA_BIFLO  ;
DR   Q7VQG3, SYA_BLOFL  ;  Q493M6, SYA_BLOPB  ;  Q2KY72, SYA_BORA1  ;
DR   Q0SNU2, SYA_BORAP  ;  Q7WHL6, SYA_BORBR  ;  O51238, SYA_BORBU  ;
DR   Q662E4, SYA_BORGA  ;  B2RZT0, SYA_BORHD  ;  Q7W6N4, SYA_BORPA  ;
DR   A9IK31, SYA_BORPD  ;  Q7VXE1, SYA_BORPE  ;  Q89I89, SYA_BRAJA  ;
DR   A5EML9, SYA_BRASB  ;  A4YXQ6, SYA_BRASO  ;  Q2YRU8, SYA_BRUA2  ;
DR   Q57CU0, SYA_BRUAB  ;  A9M5L7, SYA_BRUC2  ;  P67008, SYA_BRUME  ;
DR   A5VQX4, SYA_BRUO2  ;  B0CGZ9, SYA_BRUSI  ;  P67009, SYA_BRUSU  ;
DR   P57483, SYA_BUCAI  ;  Q8K9E7, SYA_BUCAP  ;  P59420, SYA_BUCBP  ;
DR   Q057H8, SYA_BUCCC  ;  B1YNJ6, SYA_BURA4  ;  Q1BX19, SYA_BURCA  ;
DR   B1K026, SYA_BURCC  ;  A0K6N4, SYA_BURCH  ;  Q0BG79, SYA_BURCM  ;
DR   A9AC16, SYA_BURM1  ;  A3MJ36, SYA_BURM7  ;  A2S3D4, SYA_BURM9  ;
DR   Q62KZ3, SYA_BURMA  ;  A1V3F2, SYA_BURMS  ;  A3NUB0, SYA_BURP0  ;
DR   Q3JT87, SYA_BURP1  ;  A3N8K7, SYA_BURP6  ;  B2JK72, SYA_BURP8  ;
DR   B2SZN0, SYA_BURPP  ;  Q63TF9, SYA_BURPS  ;  Q39HB7, SYA_BURS3  ;
DR   Q2SV73, SYA_BURTA  ;  A4JDM9, SYA_BURVG  ;  Q13W97, SYA_BURXL  ;
DR   A8MBI2, SYA_CALMQ  ;  A4XKP4, SYA_CALS8  ;  A7ZE62, SYA_CAMC1  ;
DR   A7GZA4, SYA_CAMC5  ;  A0RPR0, SYA_CAMFF  ;  A7I206, SYA_CAMHC  ;
DR   A8FKT2, SYA_CAMJ8  ;  A7H4N3, SYA_CAMJD  ;  Q9PI05, SYA_CAMJE  ;
DR   A1VYL8, SYA_CAMJJ  ;  Q5HVQ7, SYA_CAMJR  ;  Q5A8K2, SYA_CANAL  ;
DR   Q3AEN8, SYA_CARHZ  ;  Q9A5C1, SYA_CAUCR  ;  B0SZN4, SYA_CAUSK  ;
DR   A0RX10, SYA_CENSY  ;  A9WCR2, SYA_CHLAA  ;  Q5L512, SYA_CHLAB  ;
DR   Q3ATN3, SYA_CHLCH  ;  Q821R2, SYA_CHLCV  ;  Q255X6, SYA_CHLFF  ;
DR   Q9PLH5, SYA_CHLMU  ;  A1BD33, SYA_CHLPD  ;  Q9Z714, SYA_CHLPN  ;
DR   B0B8X5, SYA_CHLT2  ;  Q3KKU4, SYA_CHLTA  ;  B0BAK4, SYA_CHLTB  ;
DR   Q8KG04, SYA_CHLTE  ;  O84754, SYA_CHLTR  ;  Q1QZX1, SYA_CHRSD  ;
DR   Q7NXM2, SYA_CHRVO  ;  A8ANQ1, SYA_CITK8  ;  A5CRZ5, SYA_CLAM3  ;
DR   B0REK2, SYA_CLAMS  ;  Q97IG3, SYA_CLOAB  ;  A7FWJ5, SYA_CLOB1  ;
DR   A6LSF6, SYA_CLOB8  ;  B2V3W2, SYA_CLOBA  ;  B2THN0, SYA_CLOBB  ;
DR   A5I4Z5, SYA_CLOBH  ;  B1IJG7, SYA_CLOBK  ;  A7GGF1, SYA_CLOBL  ;
DR   B1KXB7, SYA_CLOBM  ;  Q18BE7, SYA_CLOD6  ;  A5N7T5, SYA_CLOK5  ;
DR   A0Q151, SYA_CLONN  ;  Q0TPH4, SYA_CLOP1  ;  Q8XJH6, SYA_CLOPE  ;
DR   Q0SS42, SYA_CLOPS  ;  Q896F2, SYA_CLOTE  ;  A3DKB6, SYA_CLOTH  ;
DR   Q487H5, SYA_COLP3  ;  P61699, SYA_CORDI  ;  Q8FT23, SYA_COREF  ;
DR   A4QEK7, SYA_CORGB  ;  Q8NQ22, SYA_CORGL  ;  Q4JVF5, SYA_CORJK  ;
DR   B1VDL4, SYA_CORU7  ;  A9KG28, SYA_COXBN  ;  A9NCN7, SYA_COXBR  ;
DR   Q83CQ6, SYA_COXBU  ;  Q0K823, SYA_CUPNH  ;  Q474F4, SYA_CUPPJ  ;
DR   B1WYQ5, SYA_CYAA5  ;  Q11V49, SYA_CYTH3  ;  Q47AU8, SYA_DECAR  ;
DR   Q3ZAE4, SYA_DEHE1  ;  A5FSU1, SYA_DEHSB  ;  Q3ZWC3, SYA_DEHSC  ;
DR   Q1IW89, SYA_DEIGD  ;  Q9RS27, SYA_DEIRA  ;  A9C0B9, SYA_DELAS  ;
DR   B1I370, SYA_DESAP  ;  Q30YS5, SYA_DESDG  ;  Q24UT2, SYA_DESHY  ;
DR   A8ZY67, SYA_DESOH  ;  Q6AQ16, SYA_DESPS  ;  A4J2K4, SYA_DESRM  ;
DR   P61700, SYA_DESVH  ;  A1VEQ6, SYA_DESVV  ;  A5EW88, SYA_DICNV  ;
DR   A8LL20, SYA_DINSH  ;  A7ZQC5, SYA_ECO24  ;  Q8X3W8, SYA_ECO57  ;
DR   B1XCM5, SYA_ECODH  ;  A8A3H4, SYA_ECOHS  ;  A1AEN7, SYA_ECOK1  ;
DR   Q0TEI3, SYA_ECOL5  ;  B1IUY2, SYA_ECOLC  ;  P00957, SYA_ECOLI  ;
DR   B1LQ15, SYA_ECOSM  ;  Q1R804, SYA_ECOUT  ;  Q3YSV8, SYA_EHRCJ  ;
DR   Q2GFL5, SYA_EHRCR  ;  Q5FH56, SYA_EHRRG  ;  Q5HC27, SYA_EHRRW  ;
DR   B2KAQ0, SYA_ELUMP  ;  Q5AQL1, SYA_EMENI  ;  A4WDQ6, SYA_ENT38  ;
DR   Q835J8, SYA_ENTFA  ;  A7MJ41, SYA_ENTS8  ;  Q6D1T0, SYA_ERWCT  ;
DR   Q2N9K5, SYA_ERYLH  ;  B1YJE5, SYA_EXIS2  ;  A7HN59, SYA_FERNB  ;
DR   B0S104, SYA_FINM2  ;  A5FIP9, SYA_FLAJ1  ;  A6H0Y3, SYA_FLAPJ  ;
DR   Q0RF65, SYA_FRAAA  ;  B0TZY8, SYA_FRAP2  ;  Q2J821, SYA_FRASC  ;
DR   A8LCW4, SYA_FRASN  ;  Q14HB9, SYA_FRAT1  ;  A7NCD9, SYA_FRATF  ;
DR   Q2A3A9, SYA_FRATH  ;  B2SH99, SYA_FRATM  ;  A0Q604, SYA_FRATN  ;
DR   Q0BLS9, SYA_FRATO  ;  Q5NFW7, SYA_FRATT  ;  A4IZ01, SYA_FRATW  ;
DR   Q8RFJ8, SYA_FUSNN  ;  Q5KWU5, SYA_GEOKA  ;  Q39Z77, SYA_GEOMG  ;
DR   P61701, SYA_GEOSL  ;  A4IR80, SYA_GEOTN  ;  A5GD98, SYA_GEOUR  ;
DR   Q7NI36, SYA_GLOVI  ;  Q5FQ21, SYA_GLUOX  ;  Q0BSD5, SYA_GRABC  ;
DR   A0LXX3, SYA_GRAFK  ;  Q7VLK0, SYA_HAEDU  ;  Q4QM86, SYA_HAEI8  ;
DR   A5UDR0, SYA_HAEIE  ;  A5UHW6, SYA_HAEIG  ;  P43815, SYA_HAEIN  ;
DR   Q0I426, SYA_HAES1  ;  B0UTE1, SYA_HAES2  ;  Q2SBT9, SYA_HAHCH  ;
DR   A1WXK5, SYA_HALHL  ;  B9LUG4, SYA_HALLT  ;  Q5UZE6, SYA_HALMA  ;
DR   B0R7I0, SYA_HALS3  ;  Q9HN24, SYA_HALSA  ;  Q18E76, SYA_HALWD  ;
DR   Q17ZF3, SYA_HELAH  ;  Q7VHV4, SYA_HELHP  ;  B0TFY7, SYA_HELMI  ;
DR   Q1CS22, SYA_HELPH  ;  Q9ZJY5, SYA_HELPJ  ;  B2UV04, SYA_HELPS  ;
DR   P56452, SYA_HELPY  ;  A9B660, SYA_HERA2  ;  A4G2S9, SYA_HERAR  ;
DR   A2BN65, SYA_HYPBU  ;  Q0BYM3, SYA_HYPNA  ;  Q5QUV7, SYA_IDILO  ;
DR   A8A8X8, SYA_IGNH4  ;  A6SVH6, SYA_JANMA  ;  Q28QV8, SYA_JANSC  ;
DR   A6WCF7, SYA_KINRD  ;  A6TCV9, SYA_KLEP7  ;  B2GIA1, SYA_KOCRD  ;
DR   B1L762, SYA_KORCO  ;  Q5FLW6, SYA_LACAC  ;  Q03R43, SYA_LACBA  ;
DR   Q03B02, SYA_LACC3  ;  Q1G947, SYA_LACDA  ;  Q048Z3, SYA_LACDB  ;
DR   Q045P6, SYA_LACGA  ;  A8YTJ0, SYA_LACH4  ;  P61702, SYA_LACJO  ;
DR   Q9CEW0, SYA_LACLA  ;  A2RME6, SYA_LACLM  ;  Q02XE9, SYA_LACLS  ;
DR   Q88V10, SYA_LACPL  ;  Q1WT32, SYA_LACS1  ;  Q38YN9, SYA_LACSS  ;
DR   Q1MP42, SYA_LAWIP  ;  Q5X4B7, SYA_LEGPA  ;  A5ICV6, SYA_LEGPC  ;
DR   Q5ZUJ9, SYA_LEGPH  ;  Q5WVQ2, SYA_LEGPL  ;  Q6AFA1, SYA_LEIXX  ;
DR   B0SGD3, SYA_LEPBA  ;  Q04QG6, SYA_LEPBJ  ;  Q054G6, SYA_LEPBL  ;
DR   B0SPT4, SYA_LEPBP  ;  B1Y1G9, SYA_LEPCP  ;  P61703, SYA_LEPIC  ;
DR   Q8F0T4, SYA_LEPIN  ;  B1MXP8, SYA_LEUCK  ;  Q03YQ2, SYA_LEUMM  ;
DR   Q92BK9, SYA_LISIN  ;  Q71ZG6, SYA_LISMF  ;  Q8Y722, SYA_LISMO  ;
DR   A0AIV3, SYA_LISW6  ;  B1HUK4, SYA_LYSSC  ;  Q2W1D9, SYA_MAGSA  ;
DR   A0L3J9, SYA_MAGSM  ;  Q65VQ5, SYA_MANSM  ;  A1TZ92, SYA_MARAV  ;
DR   Q0AQY6, SYA_MARMM  ;  A6W1F1, SYA_MARMS  ;  Q6F0K3, SYA_MESFL  ;
DR   Q11IW3, SYA_MESSB  ;  A6UUN3, SYA_META3  ;  Q8TU79, SYA_METAC  ;
DR   A7I7S4, SYA_METB6  ;  Q46CS0, SYA_METBF  ;  Q12U25, SYA_METBU  ;
DR   Q60BS6, SYA_METCA  ;  A9W5Y4, SYA_METEP  ;  Q1H3U9, SYA_METFK  ;
DR   Q2FQD6, SYA_METHJ  ;  B3E044, SYA_METI4  ;  Q57984, SYA_METJA  ;
DR   Q8TWY1, SYA_METKA  ;  A2ST90, SYA_METLZ  ;  A4FZA5, SYA_METM5  ;
DR   A9A6Q2, SYA_METM6  ;  A6VJ32, SYA_METM7  ;  Q8PWU0, SYA_METMA  ;
DR   A3CVP2, SYA_METMJ  ;  P61710, SYA_METMP  ;  B1ZC90, SYA_METPB  ;
DR   A2SI90, SYA_METPP  ;  B1M0N0, SYA_METRJ  ;  A5UKU6, SYA_METS3  ;
DR   B0UGC4, SYA_METS4  ;  A4YH91, SYA_METS5  ;  Q2NEW4, SYA_METST  ;
DR   O27718, SYA_METTH  ;  A0B6X3, SYA_METTP  ;  A6US09, SYA_METVS  ;
DR   B0JI84, SYA_MICAN  ;  Q2RHZ3, SYA_MOOTA  ;  A0QI75, SYA_MYCA1  ;
DR   A5IYK5, SYA_MYCAP  ;  Q7TYB1, SYA_MYCBO  ;  A1KLQ3, SYA_MYCBP  ;
DR   Q2SSW4, SYA_MYCCT  ;  Q7NBY8, SYA_MYCGA  ;  P47534, SYA_MYCGE  ;
DR   A4TBW4, SYA_MYCGI  ;  Q601M2, SYA_MYCH2  ;  Q4A8G4, SYA_MYCH7  ;
DR   Q4AAD3, SYA_MYCHJ  ;  Q9CCT0, SYA_MYCLE  ;  B2HNC1, SYA_MYCMM  ;
DR   Q6KHK5, SYA_MYCMO  ;  P61704, SYA_MYCMS  ;  P61705, SYA_MYCPA  ;
DR   Q8EUR6, SYA_MYCPE  ;  P75368, SYA_MYCPN  ;  Q98Q12, SYA_MYCPU  ;
DR   A0QWQ4, SYA_MYCS2  ;  Q4A633, SYA_MYCS5  ;  A3PZ44, SYA_MYCSJ  ;
DR   A1UFI3, SYA_MYCSK  ;  Q1B9I0, SYA_MYCSS  ;  A5U5Q5, SYA_MYCTA  ;
DR   O07438, SYA_MYCTU  ;  A0PPG6, SYA_MYCUA  ;  A1T8E8, SYA_MYCVP  ;
DR   Q1D084, SYA_MYXXD  ;  Q3ITT7, SYA_NATPD  ;  B2A5J7, SYA_NATTJ  ;
DR   Q5F7C4, SYA_NEIG1  ;  A9M198, SYA_NEIM0  ;  Q9JTG4, SYA_NEIMA  ;
DR   Q9JYG6, SYA_NEIMB  ;  A1KV20, SYA_NEIMF  ;  Q2GEP2, SYA_NEOSM  ;
DR   Q0AHX2, SYA_NITEC  ;  Q82TF8, SYA_NITEU  ;  Q1QMV7, SYA_NITHX  ;
DR   A9A565, SYA_NITMS  ;  Q2YD40, SYA_NITMU  ;  Q3JCK8, SYA_NITOC  ;
DR   A6Q576, SYA_NITSB  ;  Q3ST43, SYA_NITWN  ;  Q5YTJ9, SYA_NOCFA  ;
DR   A1SJC7, SYA_NOCSJ  ;  B2J876, SYA_NOSP7  ;  Q8YUD4, SYA_NOSS1  ;
DR   Q2G8V0, SYA_NOVAD  ;  Q8EPS9, SYA_OCEIH  ;  A6X0E9, SYA_OCHA4  ;
DR   Q04EQ9, SYA_OENOB  ;  Q6YQR8, SYA_ONYPE  ;  B1ZZ40, SYA_OPITP  ;
DR   A5CD03, SYA_ORITB  ;  B3CST3, SYA_ORITI  ;  A6LEZ8, SYA_PARD8  ;
DR   A1AZL6, SYA_PARDP  ;  A7HWA5, SYA_PARL1  ;  Q6MB06, SYA_PARUW  ;
DR   P57933, SYA_PASMU  ;  Q03ER8, SYA_PEDPA  ;  Q3A1W0, SYA_PELCD  ;
DR   Q3B1I7, SYA_PELLD  ;  A1ATU9, SYA_PELPD  ;  A5D3F4, SYA_PELTS  ;
DR   Q4FMX6, SYA_PELUB  ;  A9BJE0, SYA_PETMO  ;  Q7N7A5, SYA_PHOLL  ;
DR   Q6LMU3, SYA_PHOPR  ;  Q6L1Z4, SYA_PICTO  ;  A1VQK2, SYA_POLNA  ;
DR   Q129G8, SYA_POLSJ  ;  A4SZL8, SYA_POLSQ  ;  Q7MV54, SYA_PORGI  ;
DR   Q6A8I8, SYA_PROAC  ;  A3PA95, SYA_PROM0  ;  A2BZG2, SYA_PROM1  ;
DR   A8G242, SYA_PROM2  ;  A2CDK7, SYA_PROM3  ;  A9B9E5, SYA_PROM4  ;
DR   A2BTZ9, SYA_PROM5  ;  Q31DD9, SYA_PROM9  ;  Q7VEG5, SYA_PROMA  ;
DR   Q7V419, SYA_PROMM  ;  Q7V3N0, SYA_PROMP  ;  A2BNH2, SYA_PROMS  ;
DR   Q46I13, SYA_PROMT  ;  A4SGJ6, SYA_PROVI  ;  Q48G25, SYA_PSE14  ;
DR   Q15RG5, SYA_PSEA6  ;  A6VA71, SYA_PSEA7  ;  Q02I63, SYA_PSEAB  ;
DR   Q9I553, SYA_PSEAE  ;  Q1I6Z8, SYA_PSEE4  ;  Q4K843, SYA_PSEF5  ;
DR   Q3ILF3, SYA_PSEHT  ;  A4XWE2, SYA_PSEMY  ;  A5W0D9, SYA_PSEP1  ;
DR   Q3K892, SYA_PSEPF  ;  B0KR43, SYA_PSEPG  ;  Q88EI8, SYA_PSEPK  ;
DR   B1JCG9, SYA_PSEPW  ;  Q885J0, SYA_PSESM  ;  Q4ZQI4, SYA_PSEU2  ;
DR   A4VJB3, SYA_PSEU5  ;  Q4FRQ0, SYA_PSYA2  ;  Q1QA88, SYA_PSYCK  ;
DR   A1T001, SYA_PSYIN  ;  A5WFW1, SYA_PSYWF  ;  Q9UY36, SYA_PYRAB  ;
DR   Q8ZSV6, SYA_PYRAE  ;  A4WN07, SYA_PYRAR  ;  A3MXP1, SYA_PYRCJ  ;
DR   Q8U425, SYA_PYRFU  ;  O58035, SYA_PYRHO  ;  A1RT13, SYA_PYRIL  ;
DR   Q5JIL7, SYA_PYRKO  ;  Q1LQ59, SYA_RALME  ;  Q8Y193, SYA_RALSO  ;
DR   A9WSC4, SYA_RENSM  ;  Q2K7T4, SYA_RHIEC  ;  Q1MFZ9, SYA_RHIL3  ;
DR   Q98NQ5, SYA_RHILO  ;  P24075, SYA_RHILV  ;  P27866, SYA_RHIME  ;
DR   Q7UFH9, SYA_RHOBA  ;  Q221G2, SYA_RHOFD  ;  Q2ITM9, SYA_RHOP2  ;
DR   Q07R87, SYA_RHOP5  ;  P61706, SYA_RHOPA  ;  Q218Q3, SYA_RHOPB  ;
DR   Q13AB9, SYA_RHOPS  ;  Q2RQI0, SYA_RHORT  ;  A3PLJ1, SYA_RHOS1  ;
DR   Q3J0R1, SYA_RHOS4  ;  A4WV47, SYA_RHOS5  ;  Q0S0N7, SYA_RHOSR  ;
DR   A8GQ73, SYA_RICAH  ;  Q1RKG2, SYA_RICBR  ;  A8F078, SYA_RICCK  ;
DR   Q92G00, SYA_RICCN  ;  Q4UJT5, SYA_RICFE  ;  A8F323, SYA_RICM5  ;
DR   Q9ZCA4, SYA_RICPR  ;  B0BVK9, SYA_RICRO  ;  A8GU16, SYA_RICRS  ;
DR   Q68VQ7, SYA_RICTY  ;  A7NQA5, SYA_ROSCS  ;  Q165U5, SYA_ROSDO  ;
DR   A5UY81, SYA_ROSS1  ;  Q1AWA6, SYA_RUBXD  ;  A1AXE0, SYA_RUTMC  ;
DR   Q21L68, SYA_SACD2  ;  A4FBD3, SYA_SACEN  ;  A8LXY8, SYA_SALAI  ;
DR   A9MFZ1, SYA_SALAR  ;  Q57KU6, SYA_SALCH  ;  Q5PF17, SYA_SALPA  ;
DR   A9N0C1, SYA_SALPB  ;  Q2S2B6, SYA_SALRD  ;  Q8Z4D5, SYA_SALTI  ;
DR   A4X5Z0, SYA_SALTO  ;  Q8ZMK6, SYA_SALTY  ;  O13914, SYA_SCHPO  ;
DR   A8GA09, SYA_SERP5  ;  A1S4E9, SYA_SHEAM  ;  A3D783, SYA_SHEB5  ;
DR   A6WR16, SYA_SHEB8  ;  A9KYF8, SYA_SHEB9  ;  Q12PX7, SYA_SHEDO  ;
DR   Q085Z9, SYA_SHEFN  ;  B0TK15, SYA_SHEHH  ;  A3QC89, SYA_SHELP  ;
DR   Q8EBS1, SYA_SHEON  ;  A8H1T6, SYA_SHEPA  ;  A4Y931, SYA_SHEPC  ;
DR   A0KU94, SYA_SHESA  ;  A8FSV6, SYA_SHESH  ;  Q0HL60, SYA_SHESM  ;
DR   Q0HXF8, SYA_SHESR  ;  A1RHG5, SYA_SHESW  ;  B1KPS5, SYA_SHEWM  ;
DR   B2U049, SYA_SHIB3  ;  Q31X62, SYA_SHIBS  ;  Q32CN1, SYA_SHIDS  ;
DR   Q0T1C3, SYA_SHIF8  ;  Q7UBU3, SYA_SHIFL  ;  Q3YYG6, SYA_SHISS  ;
DR   Q5LRU1, SYA_SILPO  ;  Q1GHA1, SYA_SILST  ;  A6U9N4, SYA_SINMW  ;
DR   Q2NVL2, SYA_SODGM  ;  Q01XA0, SYA_SOLUE  ;  A9FRF5, SYA_SORC5  ;
DR   Q1GSD9, SYA_SPHAL  ;  A5V3L0, SYA_SPHWW  ;  A7X328, SYA_STAA1  ;
DR   A6U287, SYA_STAA2  ;  Q2FGA8, SYA_STAA3  ;  Q2FXV9, SYA_STAA8  ;
DR   A5ITE3, SYA_STAA9  ;  Q2YT60, SYA_STAAB  ;  Q5HFE4, SYA_STAAC  ;
DR   A6QHF9, SYA_STAAE  ;  P67010, SYA_STAAM  ;  P67011, SYA_STAAN  ;
DR   Q6GG85, SYA_STAAR  ;  Q6G8V1, SYA_STAAS  ;  A8Z4F6, SYA_STAAT  ;
DR   Q8NW87, SYA_STAAW  ;  Q5HNT2, SYA_STAEQ  ;  Q8CSA7, SYA_STAES  ;
DR   Q4L6W5, SYA_STAHJ  ;  A3DNI3, SYA_STAMF  ;  Q49Y56, SYA_STAS1  ;
DR   Q3K1P7, SYA_STRA1  ;  Q8E600, SYA_STRA3  ;  Q8E0C4, SYA_STRA5  ;
DR   Q827S4, SYA_STRAW  ;  Q9KXP9, SYA_STRCO  ;  A8AYI8, SYA_STRGC  ;
DR   B1W3I1, SYA_STRGG  ;  B2FL33, SYA_STRMK  ;  Q8CWY0, SYA_STRMU  ;
DR   Q99Z57, SYA_STRP1  ;  Q04JW5, SYA_STRP2  ;  P0DG24, SYA_STRP3  ;
DR   Q5XBH1, SYA_STRP6  ;  Q8P0E6, SYA_STRP8  ;  Q1JB08, SYA_STRPB  ;
DR   Q1JL53, SYA_STRPC  ;  Q1JG77, SYA_STRPD  ;  Q1J5Z4, SYA_STRPF  ;
DR   A2RDY3, SYA_STRPG  ;  B1ICI3, SYA_STRPI  ;  Q48SS4, SYA_STRPM  ;
DR   Q97Q48, SYA_STRPN  ;  P0DG25, SYA_STRPQ  ;  B2IQK0, SYA_STRPS  ;
DR   Q8DPC7, SYA_STRR6  ;  A4W221, SYA_STRS2  ;  A3CLY3, SYA_STRSV  ;
DR   A4VVR3, SYA_STRSY  ;  Q5M126, SYA_STRT1  ;  Q5M5L5, SYA_STRT2  ;
DR   Q03LZ8, SYA_STRTD  ;  P35029, SYA_SULAC  ;  Q30PA9, SYA_SULDN  ;
DR   C3MZC2, SYA_SULIA  ;  C4KIK1, SYA_SULIK  ;  C3MR87, SYA_SULIL  ;
DR   C3MXH6, SYA_SULIM  ;  C3NG91, SYA_SULIN  ;  C3N7E3, SYA_SULIY  ;
DR   A6Q747, SYA_SULNB  ;  P96041, SYA_SULSO  ;  B2V709, SYA_SULSY  ;
DR   Q971J4, SYA_SULTO  ;  Q67MV8, SYA_SYMTH  ;  Q2LPL7, SYA_SYNAS  ;
DR   Q31PW3, SYA_SYNE7  ;  A0LLA3, SYA_SYNFM  ;  Q2JTG8, SYA_SYNJA  ;
DR   Q2JLC4, SYA_SYNJB  ;  B1XP68, SYA_SYNP2  ;  Q5N4B5, SYA_SYNP6  ;
DR   A5GPF9, SYA_SYNPW  ;  Q7U3R9, SYA_SYNPX  ;  A5GWM4, SYA_SYNR3  ;
DR   Q0I6G6, SYA_SYNS3  ;  Q3AVV3, SYA_SYNS9  ;  Q3AGN4, SYA_SYNSC  ;
DR   Q0AZQ1, SYA_SYNWW  ;  P74423, SYA_SYNY3  ;  Q9HJW4, SYA_THEAC  ;
DR   Q8DH56, SYA_THEEB  ;  Q47N66, SYA_THEFY  ;  A8F866, SYA_THELT  ;
DR   A6LMH9, SYA_THEM4  ;  Q9X1B6, SYA_THEMA  ;  B1YDH4, SYA_THENV  ;
DR   A5IMH8, SYA_THEP1  ;  B0K994, SYA_THEP3  ;  A1RWQ1, SYA_THEPD  ;
DR   B0K0Q1, SYA_THEPX  ;  B1LBS9, SYA_THESQ  ;  P61707, SYA_THET2  ;
DR   P74941, SYA_THET8  ;  Q8RAH4, SYA_THETN  ;  Q97AH7, SYA_THEVO  ;
DR   Q31F91, SYA_THICR  ;  Q3SLA9, SYA_THIDA  ;  Q56273, SYA_THIFE  ;
DR   P61708, SYA_TREDE  ;  O83980, SYA_TREPA  ;  Q10VG8, SYA_TRIEI  ;
DR   Q83HV0, SYA_TROW8  ;  Q83GD1, SYA_TROWT  ;  Q0W5Q9, SYA_UNCMA  ;
DR   B1GZ43, SYA_UNCTG  ;  B1AJ08, SYA_UREP2  ;  Q9PQC2, SYA_UREPA  ;
DR   A1WIG8, SYA_VEREI  ;  A5CVU0, SYA_VESOH  ;  A5F9B7, SYA_VIBC3  ;
DR   Q56648, SYA_VIBCH  ;  Q5E7G5, SYA_VIBF1  ;  A7MYT5, SYA_VIBHB  ;
DR   Q87LR3, SYA_VIBPA  ;  Q8DC49, SYA_VIBVU  ;  Q7MHR6, SYA_VIBVY  ;
DR   Q8D2W8, SYA_WIGBR  ;  P61709, SYA_WOLPM  ;  Q7MAD3, SYA_WOLSU  ;
DR   Q5GSS5, SYA_WOLTR  ;  Q8PLQ0, SYA_XANAC  ;  Q3BUQ7, SYA_XANC5  ;
DR   Q4UTR6, SYA_XANC8  ;  B0RTY1, SYA_XANCB  ;  Q8P9X0, SYA_XANCP  ;
DR   Q2P1N1, SYA_XANOM  ;  B2SUD0, SYA_XANOP  ;  Q5GYM8, SYA_XANOR  ;
DR   A7IMR0, SYA_XANP2  ;  B2I6K2, SYA_XYLF2  ;  Q9PH22, SYA_XYLFA  ;
DR   B0U1K9, SYA_XYLFM  ;  Q87F43, SYA_XYLFT  ;  P40825, SYA_YEAST  ;
DR   A1JK09, SYA_YERE8  ;  A7FLR7, SYA_YERP3  ;  Q1C420, SYA_YERPA  ;
DR   B2K5X9, SYA_YERPB  ;  Q8ZBT8, SYA_YERPE  ;  A9R0V7, SYA_YERPG  ;
DR   Q1CLK9, SYA_YERPN  ;  A4TQ52, SYA_YERPP  ;  Q66E68, SYA_YERPS  ;
DR   B1JJA0, SYA_YERPY  ;  Q9RNN8, SYA_ZYMMO  ;
//
ID   6.1.1.8
DE   Deleted entry.
//
ID   6.1.1.9
DE   Valine--tRNA ligase.
AN   Valine translase.
AN   Valyl-tRNA synthetase.
CA   ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val).
PR   PROSITE; PDOC00161;
DR   Q86KU2, SYVC_DICDI ;  Q8SS27, SYVC_ENCCU ;  P26640, SYVC_HUMAN ;
DR   Q9Z1Q9, SYVC_MOUSE ;  C4V924, SYVC_NOSCE ;  Q04462, SYVC_RAT   ;
DR   P49696, SYVC_TAKRU ;  Q54I78, SYVM_DICDI ;  Q5ST30, SYVM_HUMAN ;
DR   Q5TM74, SYVM_MACMU ;  Q3U2A8, SYVM_MOUSE ;  Q767M3, SYVM_PIG   ;
DR   Q6MG21, SYVM_RAT   ;  O14160, SYVM_SCHPO ;  Q6F8F0, SYV_ACIAD  ;
DR   A3N2F0, SYV_ACTP2  ;  B3GYI3, SYV_ACTP7  ;  B0BR94, SYV_ACTPJ  ;
DR   Q9YAZ0, SYV_AERPE  ;  Q8UEN6, SYV_AGRT5  ;  Q0VSA8, SYV_ALCBS  ;
DR   B3ETM6, SYV_AMOA5  ;  Q5P9M8, SYV_ANAMM  ;  B7GH39, SYV_ANOFW  ;
DR   O67411, SYV_AQUAE  ;  P93736, SYV_ARATH  ;  O28059, SYV_ARCFU  ;
DR   Q5NXL5, SYV_AROAE  ;  A1K9L8, SYV_AZOSB  ;  Q81LD3, SYV_BACAN  ;
DR   Q72ZW8, SYV_BACC1  ;  Q817R6, SYV_BACCR  ;  Q633Y6, SYV_BACCZ  ;
DR   Q5LGN1, SYV_BACFN  ;  Q64XH6, SYV_BACFR  ;  Q9K8G8, SYV_BACHD  ;
DR   Q6HD68, SYV_BACHK  ;  Q65GK8, SYV_BACLD  ;  Q5WEQ4, SYV_BACSK  ;
DR   Q05873, SYV_BACSU  ;  Q89ZM4, SYV_BACTN  ;  A6L3G7, SYV_BACV8  ;
DR   Q6G2V3, SYV_BARHE  ;  Q6FZB1, SYV_BARQU  ;  Q6MQK8, SYV_BDEBA  ;
DR   B3DU23, SYV_BIFLD  ;  Q8G777, SYV_BIFLO  ;  B7GTW0, SYV_BIFLS  ;
DR   Q7VQT2, SYV_BLOFL  ;  Q493Z9, SYV_BLOPB  ;  Q7WHM6, SYV_BORBR  ;
DR   O51680, SYV_BORBU  ;  Q660D6, SYV_BORGA  ;  Q7W6P3, SYV_BORPA  ;
DR   Q7VWK6, SYV_BORPE  ;  Q89LR8, SYV_BRAJA  ;  Q8YGX8, SYV_BRUME  ;
DR   Q8G0Y3, SYV_BRUSU  ;  P57447, SYV_BUCAI  ;  Q8K9I1, SYV_BUCAP  ;
DR   Q89AG3, SYV_BUCBP  ;  Q62KW5, SYV_BURMA  ;  Q63TI8, SYV_BURPS  ;
DR   Q9U1Q4, SYV_CAEEL  ;  Q9PPE4, SYV_CAMJE  ;  Q5HV17, SYV_CAMJR  ;
DR   Q3AF87, SYV_CARHZ  ;  Q9A8N3, SYV_CAUCR  ;  Q5L5J6, SYV_CHLAB  ;
DR   Q822K4, SYV_CHLCV  ;  Q255D3, SYV_CHLFF  ;  Q9PK91, SYV_CHLMU  ;
DR   Q9Z987, SYV_CHLPN  ;  B0B7L8, SYV_CHLT2  ;  Q3KM60, SYV_CHLTA  ;
DR   B0BBT3, SYV_CHLTB  ;  Q8KC74, SYV_CHLTE  ;  O84304, SYV_CHLTR  ;
DR   Q7NUM8, SYV_CHRVO  ;  Q97GG8, SYV_CLOAB  ;  Q8XJ42, SYV_CLOPE  ;
DR   Q891R5, SYV_CLOTE  ;  Q488M6, SYV_COLP3  ;  Q6NFV0, SYV_CORDI  ;
DR   Q8FN65, SYV_COREF  ;  Q8NN37, SYV_CORGL  ;  Q4JWU8, SYV_CORJK  ;
DR   Q83DD0, SYV_COXBU  ;  Q474E1, SYV_CUPPJ  ;  Q47BG6, SYV_DECAR  ;
DR   Q3Z9C5, SYV_DEHE1  ;  Q3ZZG9, SYV_DEHSC  ;  Q9RY06, SYV_DEIRA  ;
DR   Q6AMA0, SYV_DESPS  ;  Q72E47, SYV_DESVH  ;  Q8XCB3, SYV_ECO57  ;
DR   Q8FAD1, SYV_ECOL6  ;  P07118, SYV_ECOLI  ;  Q3YT16, SYV_EHRCJ  ;
DR   Q5FF72, SYV_EHRRG  ;  Q5HC99, SYV_EHRRW  ;  Q82ZW6, SYV_ENTFA  ;
DR   Q6DA54, SYV_ERWCT  ;  A7HJX5, SYV_FERNB  ;  Q5NHZ4, SYV_FRATT  ;
DR   Q8RHK3, SYV_FUSNN  ;  Q5KWL3, SYV_GEOKA  ;  P11931, SYV_GEOSE  ;
DR   Q74BJ6, SYV_GEOSL  ;  Q7NCQ9, SYV_GLOVI  ;  Q5FN28, SYV_GLUOX  ;
DR   Q0BTM1, SYV_GRABC  ;  A0M5I5, SYV_GRAFK  ;  Q7VN93, SYV_HAEDU  ;
DR   Q4QKA4, SYV_HAEI8  ;  A5UBZ9, SYV_HAEIE  ;  A5UEN9, SYV_HAEIG  ;
DR   P43834, SYV_HAEIN  ;  P36432, SYV_HAEPA  ;  B0USP0, SYV_HAES2  ;
DR   Q5V1H0, SYV_HALMA  ;  B0R841, SYV_HALS3  ;  Q9HMG9, SYV_HALSA  ;
DR   Q7VHN2, SYV_HELHP  ;  Q9ZK61, SYV_HELPJ  ;  P56000, SYV_HELPY  ;
DR   A4G1V2, SYV_HERAR  ;  Q5QY15, SYV_IDILO  ;  A6SUQ8, SYV_JANMA  ;
DR   Q5FKW5, SYV_LACAC  ;  P36420, SYV_LACCA  ;  Q74JZ8, SYV_LACJO  ;
DR   Q9CDP6, SYV_LACLA  ;  Q88UX7, SYV_LACPL  ;  Q38XD1, SYV_LACSS  ;
DR   C1D6J9, SYV_LARHH  ;  Q5X728, SYV_LEGPA  ;  Q5ZXL2, SYV_LEGPH  ;
DR   Q5WYI0, SYV_LEGPL  ;  Q6AFZ2, SYV_LEIXX  ;  Q72V30, SYV_LEPIC  ;
DR   Q8EZT8, SYV_LEPIN  ;  Q92BG2, SYV_LISIN  ;  Q71ZB6, SYV_LISMF  ;
DR   Q8Y6X9, SYV_LISMO  ;  Q65S97, SYV_MANSM  ;  Q6F1B1, SYV_MESFL  ;
DR   Q8TLI4, SYV_METAC  ;  Q46B32, SYV_METBF  ;  Q606C1, SYV_METCA  ;
DR   Q58413, SYV_METJA  ;  Q8TVG5, SYV_METKA  ;  Q8Q024, SYV_METMA  ;
DR   Q6LZP0, SYV_METMP  ;  O26861, SYV_METTH  ;  A0B7C2, SYV_METTP  ;
DR   P67600, SYV_MYCBO  ;  Q7NAR7, SYV_MYCGA  ;  P47576, SYV_MYCGE  ;
DR   Q5ZZL4, SYV_MYCH2  ;  Q4A755, SYV_MYCH7  ;  Q4A917, SYV_MYCHJ  ;
DR   Q9CBY7, SYV_MYCLE  ;  Q6KID2, SYV_MYCMO  ;  Q6MTU2, SYV_MYCMS  ;
DR   Q73XN8, SYV_MYCPA  ;  Q8EX08, SYV_MYCPE  ;  P75304, SYV_MYCPN  ;
DR   Q98QV4, SYV_MYCPU  ;  Q4A6B0, SYV_MYCS5  ;  P67599, SYV_MYCTU  ;
DR   Q74NF3, SYV_NANEQ  ;  Q3IUE5, SYV_NATPD  ;  Q5F5W0, SYV_NEIG1  ;
DR   Q9JX22, SYV_NEIMA  ;  Q9K1H7, SYV_NEIMB  ;  P28350, SYV_NEUCR  ;
DR   Q0AIF2, SYV_NITEC  ;  Q82X51, SYV_NITEU  ;  Q2YB22, SYV_NITMU  ;
DR   Q3JC50, SYV_NITOC  ;  A6Q3R4, SYV_NITSB  ;  Q3SSP4, SYV_NITWN  ;
DR   Q5Z048, SYV_NOCFA  ;  Q8YX97, SYV_NOSS1  ;  Q8EPN2, SYV_OCEIH  ;
DR   Q6YRJ6, SYV_ONYPE  ;  A5CCE0, SYV_ORITB  ;  A6LIG7, SYV_PARD8  ;
DR   Q6MAM1, SYV_PARUW  ;  Q9CMK5, SYV_PASMU  ;  Q3A253, SYV_PELCD  ;
DR   Q4FM20, SYV_PELUB  ;  A9BIJ7, SYV_PETMO  ;  Q7MZ25, SYV_PHOLL  ;
DR   Q6LUW1, SYV_PHOPR  ;  Q6L1N5, SYV_PICTO  ;  B2RK53, SYV_PORG3  ;
DR   Q7MVD7, SYV_PORGI  ;  Q6A7F4, SYV_PROAC  ;  Q7V9I9, SYV_PROMA  ;
DR   Q7TUI9, SYV_PROMM  ;  Q7UZI3, SYV_PROMP  ;  Q46IA7, SYV_PROMT  ;
DR   Q48MF2, SYV_PSE14  ;  Q9HXH0, SYV_PSEAE  ;  Q4KHT9, SYV_PSEF5  ;
DR   Q3II73, SYV_PSEHT  ;  Q88P76, SYV_PSEPK  ;  Q887M3, SYV_PSESM  ;
DR   Q4ZXI0, SYV_PSEU2  ;  Q4FQL0, SYV_PSYA2  ;  Q9UY55, SYV_PYRAB  ;
DR   Q8ZVG2, SYV_PYRAE  ;  Q8U409, SYV_PYRFU  ;  O58052, SYV_PYRHO  ;
DR   Q5JGN7, SYV_PYRKO  ;  Q8XX80, SYV_RALSO  ;  Q98LB1, SYV_RHILO  ;
DR   Q92Q37, SYV_RHIME  ;  Q7UXH9, SYV_RHOBA  ;  Q6N6N1, SYV_RHOPA  ;
DR   A3PHJ6, SYV_RHOS1  ;  Q3J4Z5, SYV_RHOS4  ;  B9KMT9, SYV_RHOSK  ;
DR   C3PLG3, SYV_RICAE  ;  A8GPJ3, SYV_RICAH  ;  A8GVS7, SYV_RICB8  ;
DR   Q1RJ74, SYV_RICBR  ;  A8EZQ5, SYV_RICCK  ;  Q92GR9, SYV_RICCN  ;
DR   Q4UMX8, SYV_RICFE  ;  Q9ZCN6, SYV_RICPR  ;  C4K2L1, SYV_RICPU  ;
DR   B0BUV1, SYV_RICRO  ;  A8GTB4, SYV_RICRS  ;  Q68W50, SYV_RICTY  ;
DR   A8LVI6, SYV_SALAI  ;  Q57GC5, SYV_SALCH  ;  Q5PJB8, SYV_SALPA  ;
DR   Q8Z118, SYV_SALTI  ;  A4X0V0, SYV_SALTO  ;  Q8ZK31, SYV_SALTY  ;
DR   O75005, SYV_SCHPO  ;  Q8EBS5, SYV_SHEON  ;  Q31TK0, SYV_SHIBS  ;
DR   Q328S3, SYV_SHIDS  ;  Q83IM5, SYV_SHIFL  ;  Q3YU91, SYV_SHISS  ;
DR   Q5LP30, SYV_SILPO  ;  Q01PF1, SYV_SOLUE  ;  Q1GUM2, SYV_SPHAL  ;
DR   Q7X2N3, SYV_SPHEL  ;  A5V592, SYV_SPHWW  ;  A7X383, SYV_STAA1  ;
DR   A6U2D1, SYV_STAA2  ;  Q2FG72, SYV_STAA3  ;  Q2FXR8, SYV_STAA8  ;
DR   A5ITI8, SYV_STAA9  ;  Q2YTA0, SYV_STAAB  ;  Q5HFA8, SYV_STAAC  ;
DR   A6QHJ8, SYV_STAAE  ;  Q931Q1, SYV_STAAM  ;  Q99TJ8, SYV_STAAN  ;
DR   Q6GG42, SYV_STAAR  ;  Q6G8R2, SYV_STAAS  ;  A8Z2I4, SYV_STAAT  ;
DR   Q7A0P4, SYV_STAAW  ;  B9DND4, SYV_STACT  ;  Q5HNN9, SYV_STAEQ  ;
DR   Q8CS83, SYV_STAES  ;  Q4L703, SYV_STAHJ  ;  Q49Y96, SYV_STAS1  ;
DR   Q3K2S4, SYV_STRA1  ;  Q8E6S0, SYV_STRA3  ;  Q8E1B5, SYV_STRA5  ;
DR   Q82CA3, SYV_STRAW  ;  O06851, SYV_STRCO  ;  B4SJ70, SYV_STRM5  ;
DR   B2FMS2, SYV_STRMK  ;  Q8DSL1, SYV_STRMU  ;  Q99YS1, SYV_STRP1  ;
DR   P0DG64, SYV_STRP3  ;  Q5XAW8, SYV_STRP6  ;  Q8P040, SYV_STRP8  ;
DR   Q48SA4, SYV_STRPM  ;  Q97S45, SYV_STRPN  ;  P0DG65, SYV_STRPQ  ;
DR   Q8DQU7, SYV_STRR6  ;  Q5M111, SYV_STRT1  ;  Q5M5J8, SYV_STRT2  ;
DR   Q4J8X1, SYV_SULAC  ;  Q97ZK9, SYV_SULSO  ;  Q972A3, SYV_SULTO  ;
DR   Q67SJ2, SYV_SYMTH  ;  Q5N3J4, SYV_SYNP6  ;  Q7U3N4, SYV_SYNPX  ;
DR   Q55522, SYV_SYNY3  ;  Q9HM29, SYV_THEAC  ;  Q8DIS8, SYV_THEEB  ;
DR   Q47NK0, SYV_THEFY  ;  A8F8Q3, SYV_THELT  ;  Q9X2D7, SYV_THEMA  ;
DR   Q72JG7, SYV_THET2  ;  Q5SJ45, SYV_THET8  ;  P96142, SYV_THETH  ;
DR   Q8RBN5, SYV_THETN  ;  Q97CR9, SYV_THEVO  ;  Q3SL86, SYV_THIDA  ;
DR   Q73MZ2, SYV_TREDE  ;  O83998, SYV_TREPA  ;  P46216, SYV_TRIVA  ;
DR   Q83I17, SYV_TROW8  ;  Q83G51, SYV_TROWT  ;  Q9PQM4, SYV_UREPA  ;
DR   Q9KP73, SYV_VIBCH  ;  Q5E7U0, SYV_VIBF1  ;  Q87LG6, SYV_VIBPA  ;
DR   Q8DCE7, SYV_VIBVU  ;  Q7MHG1, SYV_VIBVY  ;  Q8D294, SYV_WIGBR  ;
DR   Q73HS9, SYV_WOLPM  ;  Q7M8H7, SYV_WOLSU  ;  Q5GRK0, SYV_WOLTR  ;
DR   Q8PGQ7, SYV_XANAC  ;  Q3BP98, SYV_XANC5  ;  Q4UQP3, SYV_XANC8  ;
DR   B0RVI4, SYV_XANCB  ;  Q8PCR7, SYV_XANCP  ;  Q2P7G5, SYV_XANOM  ;
DR   B2SPF0, SYV_XANOP  ;  Q5H4N5, SYV_XANOR  ;  B2I6K9, SYV_XYLF2  ;
DR   Q9PH12, SYV_XYLFA  ;  B0U1L1, SYV_XYLFM  ;  Q87F36, SYV_XYLFT  ;
DR   P07806, SYV_YEAST  ;  Q8ZBH1, SYV_YERPE  ;  Q66F11, SYV_YERPS  ;
DR   Q5NLA8, SYV_ZYMMO  ;
//
ID   6.1.1.10
DE   Methionine--tRNA ligase.
AN   Methionine translase.
AN   Methionyl-transfer ribonucleate synthetase.
AN   Methionyl-transfer ribonucleic acid synthetase.
AN   Methionyl-transfer RNA synthetase.
AN   Methionyl-tRNA synthetase.
AN   MetRS.
CA   ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-
CA   tRNA(Met).
CC   -!- In those organisms producing N-formylmethionyl-tRNA(fMet) for
CC       translation initiation, this enzyme also recognizes the initiator
CC       tRNA(fMet) and catalyzes the formation of L-methionyl-tRNA(fMet),
CC       the substrate for EC 2.1.2.9.
PR   PROSITE; PDOC00161;
DR   A8ZQ66, SYM1_ACAM1 ;  A8MG12, SYM1_ALKOO ;  A0RKM3, SYM1_BACAH ;
DR   Q81W03, SYM1_BACAN ;  Q72Y44, SYM1_BACC1 ;  Q81JA8, SYM1_BACCR ;
DR   Q6HBM0, SYM1_BACHK ;  A9FBU8, SYM1_SORC5 ;  Q81XF9, SYM2_BACAN ;
DR   Q815U6, SYM2_BACCR ;  Q2T9L8, SYMC_BOVIN ;  Q20970, SYMC_CAEEL ;
DR   Q54X95, SYMC_DICDI ;  Q8SQW5, SYMC_ENCCU ;  P56192, SYMC_HUMAN ;
DR   Q68FL6, SYMC_MOUSE ;  C4V943, SYMC_NOSCE ;  Q9UUF2, SYMC_SCHPO ;
DR   Q6PF21, SYMC_XENLA ;  P00958, SYMC_YEAST ;  A6H7E1, SYMM_BOVIN ;
DR   O74634, SYMM_CANAL ;  Q54MZ8, SYMM_DICDI ;  Q9VFL5, SYMM_DROME ;
DR   Q96GW9, SYMM_HUMAN ;  Q499X9, SYMM_MOUSE ;  Q9C2H9, SYMM_NEUCR ;
DR   O14000, SYMM_SCHPO ;  Q90YI3, SYMM_TAKRU ;  Q7T0Z0, SYMM_XENLA ;
DR   P22438, SYMM_YEAST ;  A1TTU1, SYM_ACIAC  ;  Q6FE36, SYM_ACIAD  ;
DR   B9MEX0, SYM_ACIET  ;  B7J7Y5, SYM_ACIF2  ;  B5ENA8, SYM_ACIF5  ;
DR   A1WBH1, SYM_ACISJ  ;  A3MZ70, SYM_ACTP2  ;  B3H0J7, SYM_ACTP7  ;
DR   B0BTA2, SYM_ACTPJ  ;  A6VQD5, SYM_ACTSZ  ;  A0KKF6, SYM_AERHH  ;
DR   Q9YCY3, SYM_AERPE  ;  Q8UFA2, SYM_AGRT5  ;  Q0VP51, SYM_ALCBS  ;
DR   Q0AAG6, SYM_ALHEH  ;  B6EIY5, SYM_ALISL  ;  O67298, SYM_AQUAE  ;
DR   Q9SVN5, SYM_ARATH  ;  O28819, SYM_ARCFU  ;  Q5P239, SYM_AROAE  ;
DR   A1KAG3, SYM_AZOSB  ;  C1DEF4, SYM_AZOVD  ;  C3P025, SYM_BACAA  ;
DR   C3LD96, SYM_BACAC  ;  B7JEJ3, SYM_BACC0  ;  B7INU9, SYM_BACC2  ;
DR   C1EYD5, SYM_BACC3  ;  B7HD62, SYM_BACC4  ;  B7HVW2, SYM_BACC7  ;
DR   B9J4E0, SYM_BACCQ  ;  Q5L7I8, SYM_BACFN  ;  Q64MP7, SYM_BACFR  ;
DR   Q9KGK8, SYM_BACHD  ;  P37465, SYM_BACSU  ;  Q8A3M1, SYM_BACTN  ;
DR   A6KYR3, SYM_BACV8  ;  A9VP41, SYM_BACWK  ;  Q1LT75, SYM_BAUCH  ;
DR   Q6MMA3, SYM_BDEBA  ;  C5C046, SYM_BEUC1  ;  B8DT48, SYM_BIFA0  ;
DR   A1A3N3, SYM_BIFAA  ;  P59076, SYM_BIFLO  ;  B7GP85, SYM_BIFLS  ;
DR   Q7VRX4, SYM_BLOFL  ;  Q492J8, SYM_BLOPB  ;  Q2KYS4, SYM_BORA1  ;
DR   Q0SMS1, SYM_BORAP  ;  Q7WP45, SYM_BORBR  ;  Q44951, SYM_BORBU  ;
DR   B7J2F0, SYM_BORBZ  ;  B5RME0, SYM_BORDL  ;  Q660T5, SYM_BORGA  ;
DR   B2S0T6, SYM_BORHD  ;  Q7W1D8, SYM_BORPA  ;  Q7W0F7, SYM_BORPE  ;
DR   B5RPT6, SYM_BORRA  ;  A1R019, SYM_BORT9  ;  Q8YH17, SYM_BRUME  ;
DR   P59078, SYM_BRUSU  ;  B8D8R1, SYM_BUCA5  ;  P57210, SYM_BUCAI  ;
DR   Q9ZHD7, SYM_BUCAP  ;  B8D715, SYM_BUCAT  ;  Q89AX4, SYM_BUCBP  ;
DR   B1YUT2, SYM_BURA4  ;  Q1BUH6, SYM_BURCA  ;  B1JWS3, SYM_BURCC  ;
DR   A0K9L0, SYM_BURCH  ;  B4E8E0, SYM_BURCJ  ;  Q0BCT3, SYM_BURCM  ;
DR   A9AHJ8, SYM_BURM1  ;  A3MLM5, SYM_BURM7  ;  A2SAF7, SYM_BURM9  ;
DR   Q62LE0, SYM_BURMA  ;  A1V5W0, SYM_BURMS  ;  A3NSL6, SYM_BURP0  ;
DR   Q3JUY1, SYM_BURP1  ;  A3N6Y1, SYM_BURP6  ;  Q63W90, SYM_BURPS  ;
DR   Q39DV4, SYM_BURS3  ;  Q2T087, SYM_BURTA  ;  A4JGW6, SYM_BURVG  ;
DR   Q143I7, SYM_BURXL  ;  A8MA54, SYM_CALMQ  ;  Q9PP85, SYM_CAMJE  ;
DR   B8H5U4, SYM_CAUCN  ;  Q9A884, SYM_CAUCR  ;  B0T3J0, SYM_CAUSK  ;
DR   A9WKM1, SYM_CHLAA  ;  Q5L5M3, SYM_CHLAB  ;  B8G6F7, SYM_CHLAD  ;
DR   Q3AQR4, SYM_CHLCH  ;  Q822N0, SYM_CHLCV  ;  Q255A6, SYM_CHLFF  ;
DR   B3ECI3, SYM_CHLL2  ;  Q9PL07, SYM_CHLMU  ;  A1BF81, SYM_CHLPD  ;
DR   Q9Z959, SYM_CHLPN  ;  B9LDY3, SYM_CHLSY  ;  B0B9D9, SYM_CHLT2  ;
DR   B3QT85, SYM_CHLT3  ;  Q3KMZ0, SYM_CHLTA  ;  B0BB18, SYM_CHLTB  ;
DR   P59077, SYM_CHLTE  ;  O84035, SYM_CHLTR  ;  Q1QVN7, SYM_CHRSD  ;
DR   Q7NYR7, SYM_CHRVO  ;  A8AEB2, SYM_CITK8  ;  Q97EW5, SYM_CLOAB  ;
DR   Q8XHG1, SYM_CLOPE  ;  Q899D9, SYM_CLOTE  ;  Q480H5, SYM_COLP3  ;
DR   Q6NIA5, SYM_CORDI  ;  Q8FR00, SYM_COREF  ;  A4QCN5, SYM_CORGB  ;
DR   Q8NRZ4, SYM_CORGL  ;  Q4JU18, SYM_CORJK  ;  C4LHI6, SYM_CORK4  ;
DR   B1VFI1, SYM_CORU7  ;  B6J4V8, SYM_COXB1  ;  B6J3N7, SYM_COXB2  ;
DR   A9KDF8, SYM_COXBN  ;  A9NA60, SYM_COXBR  ;  Q83B24, SYM_COXBU  ;
DR   Q0K7K0, SYM_CUPNH  ;  Q474X7, SYM_CUPPJ  ;  B3R678, SYM_CUPTR  ;
DR   Q11RM3, SYM_CYTH3  ;  Q47IK0, SYM_DECAR  ;  Q3Z9G6, SYM_DEHE1  ;
DR   A5FS74, SYM_DEHSB  ;  Q3ZZB2, SYM_DEHSC  ;  Q9RUF3, SYM_DEIRA  ;
DR   A5EY62, SYM_DICNV  ;  A8LIJ9, SYM_DINSH  ;  A7ZNT3, SYM_ECO24  ;
DR   B7UFD1, SYM_ECO27  ;  B7MEG9, SYM_ECO45  ;  B7L9Y6, SYM_ECO55  ;
DR   Q8X7E7, SYM_ECO57  ;  B5YV64, SYM_ECO5E  ;  B7NPL8, SYM_ECO7I  ;
DR   B7MX36, SYM_ECO81  ;  B7M4V9, SYM_ECO8A  ;  C4ZSJ8, SYM_ECOBW  ;
DR   B1X7K4, SYM_ECODH  ;  A8A1X8, SYM_ECOHS  ;  A1ACX8, SYM_ECOK1  ;
DR   Q0TFX8, SYM_ECOL5  ;  Q8FFX8, SYM_ECOL6  ;  B1IYW7, SYM_ECOLC  ;
DR   P00959, SYM_ECOLI  ;  B7NCE4, SYM_ECOLU  ;  B6HYV5, SYM_ECOSE  ;
DR   B1LN54, SYM_ECOSM  ;  Q1R9V8, SYM_ECOUT  ;  A4WCF6, SYM_ENT38  ;
DR   Q837B3, SYM_ENTFA  ;  A7MHL3, SYM_ENTS8  ;  Q6D7B6, SYM_ERWCT  ;
DR   B2VIF6, SYM_ERWT9  ;  B7LV75, SYM_ESCF3  ;  A5FLM7, SYM_FLAJ1  ;
DR   A6GVQ2, SYM_FLAPJ  ;  Q14GV0, SYM_FRAT1  ;  A7NAE2, SYM_FRATF  ;
DR   Q2A4Y6, SYM_FRATH  ;  A0Q556, SYM_FRATN  ;  Q0BNA8, SYM_FRATO  ;
DR   Q5NFE7, SYM_FRATT  ;  A4IXI6, SYM_FRATW  ;  Q8RE57, SYM_FUSNN  ;
DR   P23920, SYM_GEOSE  ;  A0M5Z9, SYM_GRAFK  ;  Q7VMC9, SYM_HAEDU  ;
DR   Q4QJZ5, SYM_HAEI8  ;  A5UBS8, SYM_HAEIE  ;  A5UF42, SYM_HAEIG  ;
DR   P43828, SYM_HAEIN  ;  B8F3E3, SYM_HAEPS  ;  Q0I3W7, SYM_HAES1  ;
DR   B0UV72, SYM_HAES2  ;  Q2SKU2, SYM_HAHCH  ;  A1WUY7, SYM_HALHL  ;
DR   Q5V1B3, SYM_HALMA  ;  B8D274, SYM_HALOH  ;  Q9HSA4, SYM_HALSA  ;
DR   Q18JV4, SYM_HALWD  ;  C4K759, SYM_HAMD5  ;  Q9ZKG9, SYM_HELPJ  ;
DR   P56127, SYM_HELPY  ;  A4G3S6, SYM_HERAR  ;  A2BLU2, SYM_HYPBU  ;
DR   Q0C161, SYM_HYPNA  ;  Q5R0G6, SYM_IDILO  ;  A8ABN0, SYM_IGNH4  ;
DR   A6SX05, SYM_JANMA  ;  Q28MK0, SYM_JANSC  ;  A6W6U1, SYM_KINRD  ;
DR   B5XP89, SYM_KLEP3  ;  A6TBK7, SYM_KLEP7  ;  B1L7J9, SYM_KORCO  ;
DR   Q9CHE0, SYM_LACLA  ;  Q88Z97, SYM_LACPL  ;  Q5X105, SYM_LEGPA  ;
DR   A5II55, SYM_LEGPC  ;  Q5ZRJ9, SYM_LEGPH  ;  Q5WST1, SYM_LEGPL  ;
DR   B0SHA8, SYM_LEPBA  ;  Q04Q66, SYM_LEPBJ  ;  Q054R6, SYM_LEPBL  ;
DR   B0SQX5, SYM_LEPBP  ;  B1XWM2, SYM_LEPCP  ;  Q72MR4, SYM_LEPIC  ;
DR   Q8EZD6, SYM_LEPIN  ;  Q92F90, SYM_LISIN  ;  Q724N6, SYM_LISMF  ;
DR   Q8YAF2, SYM_LISMO  ;  A0L8S1, SYM_MAGSM  ;  Q65S22, SYM_MANSM  ;
DR   A1TZ66, SYM_MARAV  ;  Q0ANL8, SYM_MARMM  ;  A6UUN1, SYM_META3  ;
DR   Q8TIU5, SYM_METAC  ;  A7I6H7, SYM_METB6  ;  Q46F18, SYM_METBF  ;
DR   Q12UQ9, SYM_METBU  ;  Q60CR0, SYM_METCA  ;  Q1H2F4, SYM_METFK  ;
DR   Q2FU77, SYM_METHJ  ;  Q58659, SYM_METJA  ;  Q8TX28, SYM_METKA  ;
DR   A2SRE2, SYM_METLZ  ;  A4FZL1, SYM_METM5  ;  A6VIW5, SYM_METM7  ;
DR   Q8PYJ4, SYM_METMA  ;  A3CX39, SYM_METMJ  ;  Q6M0E5, SYM_METMP  ;
DR   B8GFL4, SYM_METPE  ;  A2SEY3, SYM_METPP  ;  A5UJ98, SYM_METS3  ;
DR   A4YI01, SYM_METS5  ;  Q2NI31, SYM_METST  ;  O26687, SYM_METTH  ;
DR   A0B7K2, SYM_METTP  ;  A6URW2, SYM_METVS  ;  Q5UR82, SYM_MIMIV  ;
DR   P59952, SYM_MYCBO  ;  P47267, SYM_MYCGE  ;  Q9CD55, SYM_MYCLE  ;
DR   P75091, SYM_MYCPN  ;  Q50319, SYM_MYCPU  ;  O05593, SYM_MYCTU  ;
DR   Q1D8K2, SYM_MYXXD  ;  Q74MZ1, SYM_NANEQ  ;  Q3IT47, SYM_NATPD  ;
DR   Q5F585, SYM_NEIG1  ;  A9LZS9, SYM_NEIM0  ;  Q9JWP0, SYM_NEIMA  ;
DR   Q9K1Q0, SYM_NEIMB  ;  A1KR57, SYM_NEIMF  ;  Q0AES9, SYM_NITEC  ;
DR   Q82WP0, SYM_NITEU  ;  Q2Y7P0, SYM_NITMU  ;  Q3JCG5, SYM_NITOC  ;
DR   A1SGG5, SYM_NOCSJ  ;  Q8Z068, SYM_NOSS1  ;  P59079, SYM_OCEIH  ;
DR   Q9ZTS1, SYM_ORYSJ  ;  A6LFP0, SYM_PARD8  ;  A1B3P3, SYM_PARDP  ;
DR   Q6MDG0, SYM_PARUW  ;  P57838, SYM_PASMU  ;  C6DCI4, SYM_PECCP  ;
DR   Q3B3N3, SYM_PELLD  ;  B4SGQ6, SYM_PELPB  ;  Q7N6J6, SYM_PHOLL  ;
DR   Q6LSZ7, SYM_PHOPR  ;  Q6L1M5, SYM_PICTO  ;  A1VKF9, SYM_POLNA  ;
DR   Q12F12, SYM_POLSJ  ;  B2RHF5, SYM_PORG3  ;  Q7MXK7, SYM_PORGI  ;
DR   Q6A707, SYM_PROAC  ;  B4ESY6, SYM_PROMH  ;  A4SE77, SYM_PROVI  ;
DR   Q48LT7, SYM_PSE14  ;  Q15UM1, SYM_PSEA6  ;  A6V1U3, SYM_PSEA7  ;
DR   B7UWJ8, SYM_PSEA8  ;  Q02QX1, SYM_PSEAB  ;  Q9HYC7, SYM_PSEAE  ;
DR   Q1IDZ3, SYM_PSEE4  ;  Q4K758, SYM_PSEF5  ;  C3KBZ7, SYM_PSEFS  ;
DR   Q3IL10, SYM_PSEHT  ;  A4XS54, SYM_PSEMY  ;  A5VZI8, SYM_PSEP1  ;
DR   Q3K7L0, SYM_PSEPF  ;  B0KUD8, SYM_PSEPG  ;  Q88NV7, SYM_PSEPK  ;
DR   B1J1D1, SYM_PSEPW  ;  Q87XN0, SYM_PSESM  ;  Q4ZPK6, SYM_PSEU2  ;
DR   A4VJ05, SYM_PSEU5  ;  Q4FRS8, SYM_PSYA2  ;  Q1QAD0, SYM_PSYCK  ;
DR   A1SVA5, SYM_PSYIN  ;  A5WG58, SYM_PSYWF  ;  Q9V011, SYM_PYRAB  ;
DR   Q8ZU56, SYM_PYRAE  ;  A4WKG3, SYM_PYRAR  ;  A3MVB7, SYM_PYRCJ  ;
DR   Q8U221, SYM_PYRFU  ;  O58721, SYM_PYRHO  ;  A1RRE2, SYM_PYRIL  ;
DR   Q5JDZ7, SYM_PYRKO  ;  Q1LJN4, SYM_RALME  ;  Q8XWT9, SYM_RALSO  ;
DR   Q98MV8, SYM_RHILO  ;  Q92PX0, SYM_RHIME  ;  Q7URP3, SYM_RHOBA  ;
DR   Q21TB9, SYM_RHOFD  ;  A3PLG8, SYM_RHOS1  ;  Q3J0T3, SYM_RHOS4  ;
DR   A4WV24, SYM_RHOS5  ;  B9KKH3, SYM_RHOSK  ;  Q1RJZ5, SYM_RICBR  ;
DR   Q92GS6, SYM_RICCN  ;  Q4UMX2, SYM_RICFE  ;  Q9ZCP0, SYM_RICPR  ;
DR   Q68W54, SYM_RICTY  ;  A7NND5, SYM_ROSCS  ;  Q166L9, SYM_ROSDO  ;
DR   A5UUW9, SYM_ROSS1  ;  Q1AST1, SYM_RUBXD  ;  A1AWL4, SYM_RUTMC  ;
DR   Q21I21, SYM_SACD2  ;  A4F7W6, SYM_SACEN  ;  B5EXZ5, SYM_SALA4  ;
DR   A8M218, SYM_SALAI  ;  A9MKV0, SYM_SALAR  ;  Q57MI5, SYM_SALCH  ;
DR   B5FMX1, SYM_SALDC  ;  B5R0E7, SYM_SALEP  ;  B5RBZ5, SYM_SALG2  ;
DR   B4T9X0, SYM_SALHS  ;  B4SXY7, SYM_SALNS  ;  Q5PJ43, SYM_SALPA  ;
DR   A9N7I2, SYM_SALPB  ;  C0Q0Y1, SYM_SALPC  ;  B5BE81, SYM_SALPK  ;
DR   Q2S2A3, SYM_SALRD  ;  B4TNL2, SYM_SALSV  ;  Q8Z5C3, SYM_SALTI  ;
DR   A4X307, SYM_SALTO  ;  Q8ZNN4, SYM_SALTY  ;  A8GC37, SYM_SERP5  ;
DR   A1S798, SYM_SHEAM  ;  B8E958, SYM_SHEB2  ;  A3D5E5, SYM_SHEB5  ;
DR   A6WP56, SYM_SHEB8  ;  A9L4F6, SYM_SHEB9  ;  Q12MI8, SYM_SHEDO  ;
DR   Q081H3, SYM_SHEFN  ;  B0TJ05, SYM_SHEHH  ;  A3QD92, SYM_SHELP  ;
DR   Q8EDX2, SYM_SHEON  ;  A8H3V2, SYM_SHEPA  ;  A4Y7K8, SYM_SHEPC  ;
DR   A0KW24, SYM_SHESA  ;  A8FWN7, SYM_SHESH  ;  Q0HJN6, SYM_SHESM  ;
DR   Q0HVY2, SYM_SHESR  ;  A1RIY0, SYM_SHESW  ;  B1KQM2, SYM_SHEWM  ;
DR   B2TVX7, SYM_SHIB3  ;  Q323B4, SYM_SHIBS  ;  Q32EI8, SYM_SHIDS  ;
DR   Q0T324, SYM_SHIF8  ;  Q83KH0, SYM_SHIFL  ;  Q3Z096, SYM_SHISS  ;
DR   Q5LTL1, SYM_SILPO  ;  Q1GEI7, SYM_SILST  ;  Q2NUD0, SYM_SODGM  ;
DR   Q5HII6, SYM_STAAC  ;  P67578, SYM_STAAM  ;  P67579, SYM_STAAN  ;
DR   Q6GJI1, SYM_STAAR  ;  Q6GBZ8, SYM_STAAS  ;  Q8NY00, SYM_STAAW  ;
DR   Q5HRR5, SYM_STAEQ  ;  Q8CQU3, SYM_STAES  ;  Q4L3E7, SYM_STAHJ  ;
DR   Q49UZ9, SYM_STAS1  ;  Q82F60, SYM_STRAW  ;  Q9F2I9, SYM_STRCO  ;
DR   B4SRG1, SYM_STRM5  ;  B2FPT0, SYM_STRMK  ;  Q9A178, SYM_STRP1  ;
DR   P0DG48, SYM_STRP3  ;  Q5XDK8, SYM_STRP6  ;  C1C727, SYM_STRP7  ;
DR   Q8P298, SYM_STRP8  ;  P67580, SYM_STRPN  ;  P0DG49, SYM_STRPQ  ;
DR   B2IQ55, SYM_STRPS  ;  P67581, SYM_STRR6  ;  Q4J8M3, SYM_SULAC  ;
DR   C3MW97, SYM_SULIM  ;  Q9UWW2, SYM_SULSO  ;  Q971C1, SYM_SULTO  ;
DR   Q55729, SYM_SYNY3  ;  Q9HJ12, SYM_THEAC  ;  P59081, SYM_THEEB  ;
DR   Q47SZ0, SYM_THEFY  ;  O33925, SYM_THEMA  ;  B1YAZ7, SYM_THENV  ;
DR   B6YUN0, SYM_THEON  ;  A1RXT9, SYM_THEPD  ;  B9KZR0, SYM_THERP  ;
DR   P23395, SYM_THET8  ;  Q8RDD1, SYM_THETN  ;  Q979B7, SYM_THEVO  ;
DR   Q31GU1, SYM_THICR  ;  Q3SKG8, SYM_THIDA  ;  C4LEX5, SYM_TOLAT  ;
DR   Q73NT9, SYM_TREDE  ;  O83776, SYM_TREPA  ;  Q0W0H2, SYM_UNCMA  ;
DR   Q9PQU6, SYM_UREPA  ;  A1WRC4, SYM_VEREI  ;  A5CWL9, SYM_VESOH  ;
DR   A5F2P8, SYM_VIBC3  ;  Q9KT69, SYM_VIBCH  ;  Q5E3Z7, SYM_VIBF1  ;
DR   B5FG53, SYM_VIBFM  ;  A7MZT3, SYM_VIBHB  ;  Q87N07, SYM_VIBPA  ;
DR   B7VLW8, SYM_VIBSL  ;  Q8D8F2, SYM_VIBVU  ;  Q7MM14, SYM_VIBVY  ;
DR   Q8D219, SYM_WIGBR  ;  Q8PMP0, SYM_XANAC  ;  Q3BVP1, SYM_XANC5  ;
DR   Q4USM5, SYM_XANC8  ;  B0RWA1, SYM_XANCB  ;  Q8PAY7, SYM_XANCP  ;
DR   Q2P4E9, SYM_XANOM  ;  B2SRQ4, SYM_XANOP  ;  Q5H1J3, SYM_XANOR  ;
DR   B2I7S0, SYM_XYLF2  ;  Q9PFV8, SYM_XYLFA  ;  B0U472, SYM_XYLFM  ;
DR   Q87B68, SYM_XYLFT  ;  A1JTX6, SYM_YERE8  ;  A7FJJ6, SYM_YERP3  ;
DR   Q1C9T8, SYM_YERPA  ;  B2JZK3, SYM_YERPB  ;  Q8ZG01, SYM_YERPE  ;
DR   A9R2M7, SYM_YERPG  ;  Q1CGU4, SYM_YERPN  ;  A4TKM9, SYM_YERPP  ;
DR   Q66C72, SYM_YERPS  ;  B1JPY8, SYM_YERPY  ;
//
ID   6.1.1.11
DE   Serine--tRNA ligase.
AN   Serine translase.
AN   SerRS.
AN   Seryl-transfer ribonucleate synthetase.
AN   Seryl-transfer ribonucleic acid synthetase.
AN   Seryl-transfer RNA synthetase.
AN   Seryl-tRNA synthetase.
CA   ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser).
CC   -!- This enzyme also recognizes tRNA(Sec), the special tRNA for
CC       selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec),
CC       the substrate for EC 2.9.1.1.
PR   PROSITE; PDOC00363;
DR   Q97N17, SYS1_CLOAB ;  Q839Q8, SYS1_ENTFA ;  Q88Z60, SYS1_LACPL ;
DR   Q82FK8, SYS1_STRAW ;  Q97N21, SYS2_CLOAB ;  Q82YY9, SYS2_ENTFA ;
DR   Q88XZ7, SYS2_LACPL ;  A6UX37, SYS2_META3 ;  Q46AN5, SYS2_METBF ;
DR   Q12TN5, SYS2_METBU ;  Q58477, SYS2_METJA ;  Q8TVD2, SYS2_METKA ;
DR   A4FXR4, SYS2_METM5 ;  A9AB64, SYS2_METM6 ;  A6VFH1, SYS2_METM7 ;
DR   O30520, SYS2_METMP ;  O27194, SYS2_METTH ;  A0B5E9, SYS2_METTP ;
DR   A6UN84, SYS2_METVS ;  Q82KS8, SYS2_STRAW ;  Q9GMB8, SYSC_BOVIN ;
DR   Q18678, SYSC_CAEEL ;  Q9HGT6, SYSC_CANAL ;  P26636, SYSC_CRIGR ;
DR   Q7KWQ2, SYSC_DICDI ;  P49591, SYSC_HUMAN ;  Q4R4U9, SYSC_MACFA ;
DR   P26638, SYSC_MOUSE ;  Q8I5P7, SYSC_PLAF7 ;  Q5R9K9, SYSC_PONAB ;
DR   P13642, SYSC_RABIT ;  Q6P799, SYSC_RAT   ;  O14018, SYSC_SCHPO ;
DR   P07284, SYSC_YEAST ;  Q9N0F3, SYSM_BOVIN ;  Q9NP81, SYSM_HUMAN ;
DR   Q9JJL8, SYSM_MOUSE ;  Q9UTB2, SYSM_SCHPO ;  P38705, SYSM_YEAST ;
DR   B0BYR8, SYS_ACAM1  ;  A9NE72, SYS_ACHLI  ;  A1TTM6, SYS_ACIAC  ;
DR   Q6F8G5, SYS_ACIAD  ;  B7GXI2, SYS_ACIB3  ;  B7I6V5, SYS_ACIB5  ;
DR   B2HXU5, SYS_ACIBC  ;  A0LWR6, SYS_ACIC1  ;  C1F4G5, SYS_ACIC5  ;
DR   A5FX43, SYS_ACICJ  ;  B9MEG7, SYS_ACIET  ;  B7J4C9, SYS_ACIF2  ;
DR   B5EMC5, SYS_ACIF5  ;  A1WBD4, SYS_ACISJ  ;  A3N0M8, SYS_ACTP2  ;
DR   B3H1K7, SYS_ACTP7  ;  B0BPF3, SYS_ACTPJ  ;  A6VNC3, SYS_ACTSZ  ;
DR   A0KJE8, SYS_AERHH  ;  Q9YAG3, SYS_AERPE  ;  A4SNK6, SYS_AERS4  ;
DR   B9JEH1, SYS_AGRRK  ;  Q8UEQ2, SYS_AGRT5  ;  B9JXD8, SYS_AGRVS  ;
DR   B2UPP6, SYS_AKKM8  ;  Q0VQ06, SYS_ALCBS  ;  Q0A7Z2, SYS_ALHEH  ;
DR   B6ENN5, SYS_ALISL  ;  A6TJ99, SYS_ALKMQ  ;  A8MEB3, SYS_ALKOO  ;
DR   B4RZU0, SYS_ALTMD  ;  B8J8M9, SYS_ANAD2  ;  Q2IGB1, SYS_ANADE  ;
DR   Q5PAH7, SYS_ANAMM  ;  Q2GKS1, SYS_ANAPZ  ;  B4UFJ8, SYS_ANASK  ;
DR   B9MQM8, SYS_ANATD  ;  Q3MCE0, SYS_ANAVT  ;  O66647, SYS_AQUAE  ;
DR   Q39230, SYS_ARATH  ;  A8ERP6, SYS_ARCB4  ;  O28244, SYS_ARCFU  ;
DR   Q5NXU8, SYS_AROAE  ;  A1R120, SYS_ARTAT  ;  B8H9Q1, SYS_ARTCA  ;
DR   A0JR71, SYS_ARTS2  ;  Q2NIJ4, SYS_AYWBP  ;  A8I4J4, SYS_AZOC5  ;
DR   A1K581, SYS_AZOSB  ;  C1DKY8, SYS_AZOVD  ;  A7Z0D5, SYS_BACA2  ;
DR   C3P9G2, SYS_BACAA  ;  C3LIY9, SYS_BACAC  ;  A0R891, SYS_BACAH  ;
DR   Q81W25, SYS_BACAN  ;  B7JJC8, SYS_BACC0  ;  Q73FJ3, SYS_BACC1  ;
DR   B7IS31, SYS_BACC2  ;  C1ES19, SYS_BACC3  ;  B7HII5, SYS_BACC4  ;
DR   B7HPS8, SYS_BACC7  ;  A7GJT0, SYS_BACCN  ;  B9IYI0, SYS_BACCQ  ;
DR   Q81JC4, SYS_BACCR  ;  Q63HF6, SYS_BACCZ  ;  Q9KGN4, SYS_BACHD  ;
DR   Q6HPZ8, SYS_BACHK  ;  Q65PL0, SYS_BACLD  ;  A8FAD7, SYS_BACP2  ;
DR   Q5WM19, SYS_BACSK  ;  P37464, SYS_BACSU  ;  A1US81, SYS_BARBK  ;
DR   Q6G419, SYS_BARHE  ;  Q6G036, SYS_BARQU  ;  A9IS21, SYS_BART1  ;
DR   Q1LTE8, SYS_BAUCH  ;  Q6MRK1, SYS_BDEBA  ;  B2IJG1, SYS_BEII9  ;
DR   C5BWI5, SYS_BEUC1  ;  B8DW52, SYS_BIFA0  ;  A1A0B7, SYS_BIFAA  ;
DR   B3DQG7, SYS_BIFLD  ;  Q8G3W7, SYS_BIFLO  ;  B7GN83, SYS_BIFLS  ;
DR   Q7VR39, SYS_BLOFL  ;  Q492S4, SYS_BLOPB  ;  Q2KWF5, SYS_BORA1  ;
DR   Q0SNT6, SYS_BORAP  ;  Q7WCM7, SYS_BORBR  ;  O51244, SYS_BORBU  ;
DR   B7J1F4, SYS_BORBZ  ;  B5RL50, SYS_BORDL  ;  Q662D8, SYS_BORGA  ;
DR   Q7W545, SYS_BORPA  ;  A9IGG4, SYS_BORPD  ;  Q7VW08, SYS_BORPE  ;
DR   B5RR43, SYS_BORRA  ;  C0R1U9, SYS_BRAHW  ;  Q89L00, SYS_BRAJA  ;
DR   A5EJV9, SYS_BRASB  ;  A4YV70, SYS_BRASO  ;  C0ZH54, SYS_BREBN  ;
DR   B2S5B8, SYS_BRUA1  ;  Q2YNM6, SYS_BRUA2  ;  Q57DM2, SYS_BRUAB  ;
DR   A9MAQ8, SYS_BRUC2  ;  C0RIL8, SYS_BRUMB  ;  Q8YGS6, SYS_BRUME  ;
DR   B0CLL0, SYS_BRUSI  ;  Q8G139, SYS_BRUSU  ;  B8D9A3, SYS_BUCA5  ;
DR   P57398, SYS_BUCAI  ;  P81434, SYS_BUCAP  ;  B8D7K5, SYS_BUCAT  ;
DR   P59553, SYS_BUCBP  ;  B1YUL5, SYS_BURA4  ;  B1JX98, SYS_BURCC  ;
DR   Q9AEN2, SYS_BURCE  ;  A0K5F5, SYS_BURCH  ;  B4EBR4, SYS_BURCJ  ;
DR   Q0BHH5, SYS_BURCM  ;  A9AES3, SYS_BURM1  ;  A3MMN2, SYS_BURM7  ;
DR   A2S9G4, SYS_BURM9  ;  Q62HY1, SYS_BURMA  ;  A1V1N6, SYS_BURMS  ;
DR   A3NY56, SYS_BURP0  ;  Q3JPQ8, SYS_BURP1  ;  A3NCC8, SYS_BURP6  ;
DR   B2JEF5, SYS_BURP8  ;  B2T1A6, SYS_BURPP  ;  Q63RS1, SYS_BURPS  ;
DR   Q39IN7, SYS_BURS3  ;  Q2SY90, SYS_BURTA  ;  A4JCA3, SYS_BURVG  ;
DR   Q143D9, SYS_BURXL  ;  A4XJH1, SYS_CALS8  ;  A7ZBR7, SYS_CAMC1  ;
DR   A7GWY9, SYS_CAMC5  ;  A0RQK5, SYS_CAMFF  ;  A7HZX6, SYS_CAMHC  ;
DR   A8FKH6, SYS_CAMJ8  ;  A7H4Y8, SYS_CAMJD  ;  Q9PIB3, SYS_CAMJE  ;
DR   A1VYA9, SYS_CAMJJ  ;  Q5HW78, SYS_CAMJR  ;  B9KFN2, SYS_CAMLR  ;
DR   Q3A8Q5, SYS_CARHZ  ;  B8GX53, SYS_CAUCN  ;  Q9A6T4, SYS_CAUCR  ;
DR   B0T1Q3, SYS_CAUSK  ;  B3PL38, SYS_CELJU  ;  A0RTS8, SYS_CENSY  ;
DR   A9WE34, SYS_CHLAA  ;  Q5L4Z0, SYS_CHLAB  ;  B8G8S1, SYS_CHLAD  ;
DR   Q3ASQ9, SYS_CHLCH  ;  Q821P2, SYS_CHLCV  ;  Q255Z9, SYS_CHLFF  ;
DR   B3EF00, SYS_CHLL2  ;  Q9PLJ7, SYS_CHLMU  ;  B3QM90, SYS_CHLP8  ;
DR   B3ENZ9, SYS_CHLPB  ;  A1BHA5, SYS_CHLPD  ;  Q9Z736, SYS_CHLPN  ;
DR   B9LIV1, SYS_CHLSY  ;  B0B8V5, SYS_CHLT2  ;  B3QV79, SYS_CHLT3  ;
DR   Q3KKW5, SYS_CHLTA  ;  B0BAI4, SYS_CHLTB  ;  Q8KES6, SYS_CHLTE  ;
DR   O84734, SYS_CHLTR  ;  Q1QV43, SYS_CHRSD  ;  Q7NY99, SYS_CHRVO  ;
DR   A8AII9, SYS_CITK8  ;  A5CNA2, SYS_CLAM3  ;  B0RCF1, SYS_CLAMS  ;
DR   A7FQ53, SYS_CLOB1  ;  C3KXS1, SYS_CLOB6  ;  B2UX54, SYS_CLOBA  ;
DR   B2THC5, SYS_CLOBB  ;  A5HXR1, SYS_CLOBH  ;  C1FPI7, SYS_CLOBJ  ;
DR   B1IDV4, SYS_CLOBK  ;  A7G9C5, SYS_CLOBL  ;  B1L1M0, SYS_CLOBM  ;
DR   B9DXT9, SYS_CLOK1  ;  A5N469, SYS_CLOK5  ;  A0Q3T2, SYS_CLONN  ;
DR   Q0TV53, SYS_CLOP1  ;  Q8XPE9, SYS_CLOPE  ;  Q0SWW9, SYS_CLOPS  ;
DR   Q899T6, SYS_CLOTE  ;  A3DI04, SYS_CLOTH  ;  Q480Q2, SYS_COLP3  ;
DR   B5Y8D8, SYS_COPPD  ;  Q6NEN2, SYS_CORDI  ;  Q8FLY5, SYS_COREF  ;
DR   Q8NLP6, SYS_CORGL  ;  C4LGQ1, SYS_CORK4  ;  B6J7K7, SYS_COXB1  ;
DR   B6IZT4, SYS_COXB2  ;  A9KFP4, SYS_COXBN  ;  A9NDR1, SYS_COXBR  ;
DR   P39919, SYS_COXBU  ;  Q0KDK9, SYS_CUPNH  ;  B3R376, SYS_CUPTR  ;
DR   B8HL86, SYS_CYAP4  ;  B7KCF5, SYS_CYAP7  ;  B7JY63, SYS_CYAP8  ;
DR   Q47GH9, SYS_DECAR  ;  Q3Z8Y0, SYS_DEHE1  ;  A5FRN4, SYS_DEHSB  ;
DR   Q3ZWY0, SYS_DEHSC  ;  Q1IZU9, SYS_DEIGD  ;  Q9RUV5, SYS_DEIRA  ;
DR   A9BYK5, SYS_DELAS  ;  B8FNA6, SYS_DESAA  ;  C6BS43, SYS_DESAD  ;
DR   C0QLD3, SYS_DESAH  ;  B1I161, SYS_DESAP  ;  B8J4S2, SYS_DESDA  ;
DR   Q316Z9, SYS_DESDG  ;  B8FXX3, SYS_DESHD  ;  Q252J5, SYS_DESHY  ;
DR   B8D3V1, SYS_DESK1  ;  C4XHA0, SYS_DESMR  ;  A8ZXS1, SYS_DESOH  ;
DR   Q6AMD2, SYS_DESPS  ;  A4J0G4, SYS_DESRM  ;  Q72FH6, SYS_DESVH  ;
DR   B8DQP8, SYS_DESVM  ;  A1VH35, SYS_DESVV  ;  A5EXS3, SYS_DICNV  ;
DR   B5YEY8, SYS_DICT6  ;  B8E0R9, SYS_DICTD  ;  A7ZJW2, SYS_ECO24  ;
DR   B7UMY4, SYS_ECO27  ;  B7MHK5, SYS_ECO45  ;  B7LD85, SYS_ECO55  ;
DR   P0A8L3, SYS_ECO57  ;  B5YT28, SYS_ECO5E  ;  B7NM82, SYS_ECO7I  ;
DR   B7MRV6, SYS_ECO81  ;  B7M821, SYS_ECO8A  ;  C4ZQ19, SYS_ECOBW  ;
DR   B1X833, SYS_ECODH  ;  A7ZYJ7, SYS_ECOHS  ;  A1A9D6, SYS_ECOK1  ;
DR   Q0TJF7, SYS_ECOL5  ;  P0A8L2, SYS_ECOL6  ;  B1IWN0, SYS_ECOLC  ;
DR   P0A8L1, SYS_ECOLI  ;  B7NAP4, SYS_ECOLU  ;  B6I8W4, SYS_ECOSE  ;
DR   B1LJX0, SYS_ECOSM  ;  Q1RE21, SYS_ECOUT  ;  C5BE90, SYS_EDWI9  ;
DR   Q3YS14, SYS_EHRCJ  ;  Q5FGY8, SYS_EHRRG  ;  Q5HB76, SYS_EHRRW  ;
DR   B2KEV5, SYS_ELUMP  ;  Q8SS48, SYS_ENCCU  ;  A4W8R7, SYS_ENT38  ;
DR   A7MER7, SYS_ENTS8  ;  Q6D3V0, SYS_ERWCT  ;  B2VC55, SYS_ERWT9  ;
DR   Q2NDM7, SYS_ERYLH  ;  B7LN61, SYS_ESCF3  ;  B1YGC4, SYS_EXIS2  ;
DR   C4KZX8, SYS_EXISA  ;  A7HN78, SYS_FERNB  ;  B0RZY8, SYS_FINM2  ;
DR   B0TYM9, SYS_FRAP2  ;  Q14GR3, SYS_FRAT1  ;  A7NDJ8, SYS_FRATF  ;
DR   Q2A2B0, SYS_FRATH  ;  B2SDH2, SYS_FRATM  ;  A0Q5M5, SYS_FRATN  ;
DR   Q0BKX7, SYS_FRATO  ;  Q5NFB0, SYS_FRATT  ;  A4IZ69, SYS_FRATW  ;
DR   Q8RH11, SYS_FUSNN  ;  C1A8M5, SYS_GEMAT  ;  B5E8F6, SYS_GEOBB  ;
DR   Q5L3Y0, SYS_GEOKA  ;  B3EAQ9, SYS_GEOLS  ;  Q39PU1, SYS_GEOMG  ;
DR   B9M3Q9, SYS_GEOSF  ;  Q74H55, SYS_GEOSL  ;  C6E7Z3, SYS_GEOSM  ;
DR   C5D340, SYS_GEOSW  ;  A4IJ96, SYS_GEOTN  ;  A5GD47, SYS_GEOUR  ;
DR   Q7NMP9, SYS_GLOVI  ;  A9HLG2, SYS_GLUDA  ;  Q5FQ48, SYS_GLUOX  ;
DR   Q0BSQ2, SYS_GRABC  ;  Q7VM65, SYS_HAEDU  ;  Q4QP70, SYS_HAEI8  ;
DR   A5UB32, SYS_HAEIE  ;  A5UFR9, SYS_HAEIG  ;  P43833, SYS_HAEIN  ;
DR   B8F4Q5, SYS_HAEPS  ;  Q0I471, SYS_HAES1  ;  B0UUT7, SYS_HAES2  ;
DR   Q2SJB8, SYS_HAHCH  ;  A1WWU7, SYS_HALHL  ;  B9LQZ7, SYS_HALLT  ;
DR   P54221, SYS_HALMA  ;  B8CZZ9, SYS_HALOH  ;  B0R6Z8, SYS_HALS3  ;
DR   Q9HNJ8, SYS_HALSA  ;  Q18FL9, SYS_HALWD  ;  C4K5T8, SYS_HAMD5  ;
DR   Q17V90, SYS_HELAH  ;  O81983, SYS_HELAN  ;  Q7VG34, SYS_HELHP  ;
DR   B0TAQ9, SYS_HELMI  ;  B6JNX8, SYS_HELP2  ;  B5Z999, SYS_HELPG  ;
DR   Q1CRC2, SYS_HELPH  ;  Q9ZJD9, SYS_HELPJ  ;  B2UVM6, SYS_HELPS  ;
DR   P56458, SYS_HELPY  ;  A9AY92, SYS_HERA2  ;  A4G3W7, SYS_HERAR  ;
DR   B4U7F1, SYS_HYDS0  ;  A2BM70, SYS_HYPBU  ;  Q0C0W2, SYS_HYPNA  ;
DR   Q5R0B0, SYS_IDILO  ;  A8AB67, SYS_IGNH4  ;  A6SX50, SYS_JANMA  ;
DR   Q28TH5, SYS_JANSC  ;  B5XY99, SYS_KLEP3  ;  A6T6Z0, SYS_KLEP7  ;
DR   B2GGG9, SYS_KOCRD  ;  B1L5G0, SYS_KORCO  ;  C5CGC3, SYS_KOSOT  ;
DR   Q5FIN5, SYS_LACAC  ;  Q03PU5, SYS_LACBA  ;  Q037M7, SYS_LACC3  ;
DR   B3W8V7, SYS_LACCB  ;  Q1G8N2, SYS_LACDA  ;  Q048F6, SYS_LACDB  ;
DR   B2GF13, SYS_LACF3  ;  Q041F5, SYS_LACGA  ;  A8YWU9, SYS_LACH4  ;
DR   Q74HZ5, SYS_LACJO  ;  Q9CEX2, SYS_LACLA  ;  A2RJ76, SYS_LACLM  ;
DR   Q02XG6, SYS_LACLS  ;  A5VHP5, SYS_LACRD  ;  B2G575, SYS_LACRJ  ;
DR   Q1WVB3, SYS_LACS1  ;  Q38UM4, SYS_LACSS  ;  C1DBY7, SYS_LARHH  ;
DR   Q5X7N0, SYS_LEGPA  ;  A5IH84, SYS_LEGPC  ;  Q5ZY59, SYS_LEGPH  ;
DR   Q5WZ31, SYS_LEGPL  ;  Q6AH61, SYS_LEIXX  ;  B0S8Z4, SYS_LEPBA  ;
DR   Q04WE1, SYS_LEPBJ  ;  Q04XA4, SYS_LEPBL  ;  B0SRZ1, SYS_LEPBP  ;
DR   B1Y0I6, SYS_LEPCP  ;  Q72LS1, SYS_LEPIC  ;  Q8EY78, SYS_LEPIN  ;
DR   B1MW28, SYS_LEUCK  ;  Q03ZQ9, SYS_LEUMM  ;  Q926Z9, SYS_LISIN  ;
DR   C1L082, SYS_LISMC  ;  Q71W17, SYS_LISMF  ;  B8DD73, SYS_LISMH  ;
DR   Q8Y3T4, SYS_LISMO  ;  A0AM81, SYS_LISW6  ;  B1HS47, SYS_LYSSC  ;
DR   B9E909, SYS_MACCJ  ;  Q2W4A0, SYS_MAGSA  ;  A0L6J8, SYS_MAGSM  ;
DR   Q65SK3, SYS_MANSM  ;  A1U0W2, SYS_MARAV  ;  Q0AND9, SYS_MARMM  ;
DR   A6W0C9, SYS_MARMS  ;  Q6F2A0, SYS_MESFL  ;  Q11HC8, SYS_MESSB  ;
DR   Q8TIU3, SYS_METAC  ;  A7I890, SYS_METB6  ;  Q46F20, SYS_METBF  ;
DR   B7KPY5, SYS_METC4  ;  Q606P5, SYS_METCA  ;  A9VY49, SYS_METEP  ;
DR   Q1H290, SYS_METFK  ;  Q2FS27, SYS_METHJ  ;  B3DX68, SYS_METI4  ;
DR   A2SRC6, SYS_METLZ  ;  Q8PYJ6, SYS_METMA  ;  A3CTP4, SYS_METMJ  ;
DR   B8IN20, SYS_METNO  ;  B1ZJ12, SYS_METPB  ;  A2SJA7, SYS_METPP  ;
DR   B0UD12, SYS_METS4  ;  A4YI40, SYS_METS5  ;  B8ELG9, SYS_METSB  ;
DR   Q2NEU9, SYS_METST  ;  B0JTT9, SYS_MICAN  ;  C5C878, SYS_MICLC  ;
DR   Q2RMH8, SYS_MOOTA  ;  A0Q999, SYS_MYCA1  ;  B3PNG9, SYS_MYCA5  ;
DR   B1MEI9, SYS_MYCA9  ;  A5IXJ4, SYS_MYCAP  ;  P67562, SYS_MYCBO  ;
DR   A1KQG9, SYS_MYCBP  ;  C1AIU0, SYS_MYCBT  ;  Q2SR32, SYS_MYCCT  ;
DR   Q7NAD6, SYS_MYCGA  ;  P47251, SYS_MYCGE  ;  B8ZTU5, SYS_MYCLB  ;
DR   Q9CDC1, SYS_MYCLE  ;  B2HMM1, SYS_MYCMM  ;  Q6KIJ8, SYS_MYCMO  ;
DR   Q6MUG5, SYS_MYCMS  ;  Q745I8, SYS_MYCPA  ;  Q8EW01, SYS_MYCPE  ;
DR   P75107, SYS_MYCPN  ;  Q98RH5, SYS_MYCPU  ;  A0R638, SYS_MYCS2  ;
DR   A3Q7P6, SYS_MYCSJ  ;  A1UN98, SYS_MYCSK  ;  Q1B1V1, SYS_MYCSS  ;
DR   A5U9G3, SYS_MYCTA  ;  P67561, SYS_MYCTU  ;  A0PX13, SYS_MYCUA  ;
DR   A1TGX4, SYS_MYCVP  ;  Q1DAZ4, SYS_MYXXD  ;  B2A2Z8, SYS_NATTJ  ;
DR   B9L7B0, SYS_NAUPA  ;  Q5F752, SYS_NEIG1  ;  B4RN50, SYS_NEIG2  ;
DR   A9M1Q6, SYS_NEIM0  ;  Q9JT77, SYS_NEIMA  ;  Q9JY95, SYS_NEIMB  ;
DR   A1KV93, SYS_NEIMF  ;  Q0AJC4, SYS_NITEC  ;  Q820S5, SYS_NITEU  ;
DR   Q1QME2, SYS_NITHX  ;  A9A4V3, SYS_NITMS  ;  Q2YCN3, SYS_NITMU  ;
DR   Q3JCA2, SYS_NITOC  ;  A6Q4S8, SYS_NITSB  ;  Q5Z3K9, SYS_NOCFA  ;
DR   A1SD34, SYS_NOCSJ  ;  B2J6K8, SYS_NOSP7  ;  Q8YQ59, SYS_NOSS1  ;
DR   Q2GA28, SYS_NOVAD  ;  Q8EU77, SYS_OCEIH  ;  Q04GM3, SYS_OENOB  ;
DR   B6JFP3, SYS_OLICO  ;  Q6YRD2, SYS_ONYPE  ;  A5CDU5, SYS_ORITB  ;
DR   B3CQX9, SYS_ORITI  ;  A1B4S2, SYS_PARDP  ;  A7HXK4, SYS_PARL1  ;
DR   P57836, SYS_PASMU  ;  C6DF54, SYS_PECCP  ;  Q03EA5, SYS_PEDPA  ;
DR   Q3A7Q8, SYS_PELCD  ;  Q3B5A4, SYS_PELLD  ;  B4SF71, SYS_PELPB  ;
DR   A1ALM7, SYS_PELPD  ;  A5D6D5, SYS_PELTS  ;  Q4FM02, SYS_PELUB  ;
DR   A9BEX3, SYS_PETMO  ;  B4RDI1, SYS_PHEZH  ;  Q7N6E7, SYS_PHOLL  ;
DR   Q6LT00, SYS_PHOPR  ;  B3R0F5, SYS_PHYMT  ;  Q6KZN5, SYS_PICTO  ;
DR   A1VSK4, SYS_POLNA  ;  B1XVE1, SYS_POLNS  ;  A4SWP6, SYS_POLSQ  ;
DR   B4S6M3, SYS_PROA2  ;  Q6A5P0, SYS_PROAC  ;  A3PE37, SYS_PROM0  ;
DR   A2C409, SYS_PROM1  ;  A8G5Y6, SYS_PROM2  ;  A2C798, SYS_PROM3  ;
DR   A2BXQ6, SYS_PROM5  ;  Q7VAZ8, SYS_PROMA  ;  B4EV93, SYS_PROMH  ;
DR   Q7V608, SYS_PROMM  ;  Q7V0R7, SYS_PROMP  ;  A2BSA4, SYS_PROMS  ;
DR   Q46JN0, SYS_PROMT  ;  A4SFD5, SYS_PROVI  ;  Q48H74, SYS_PSE14  ;
DR   Q15T16, SYS_PSEA6  ;  A6V4H5, SYS_PSEA7  ;  B7UW10, SYS_PSEA8  ;
DR   Q02NA4, SYS_PSEAB  ;  Q9I0M6, SYS_PSEAE  ;  Q1IBD0, SYS_PSEE4  ;
DR   Q4K9V7, SYS_PSEF5  ;  C3JY54, SYS_PSEFS  ;  Q3IH21, SYS_PSEHT  ;
DR   A4XUX4, SYS_PSEMY  ;  A5W1H6, SYS_PSEP1  ;  Q3KA84, SYS_PSEPF  ;
DR   B0KLW8, SYS_PSEPG  ;  Q88FT2, SYS_PSEPK  ;  B1JBE0, SYS_PSEPW  ;
DR   Q87ZS9, SYS_PSESM  ;  Q4ZRL5, SYS_PSEU2  ;  A4VLU7, SYS_PSEU5  ;
DR   Q4FR92, SYS_PSYA2  ;  Q1Q9M6, SYS_PSYCK  ;  A1SVE4, SYS_PSYIN  ;
DR   A5WFN9, SYS_PSYWF  ;  Q9UZ21, SYS_PYRAB  ;  Q8ZTP4, SYS_PYRAE  ;
DR   A3MX52, SYS_PYRCJ  ;  Q8U1K2, SYS_PYRFU  ;  O58441, SYS_PYRHO  ;
DR   A1RRX4, SYS_PYRIL  ;  Q5JE75, SYS_PYRKO  ;  Q1LQJ5, SYS_RALME  ;
DR   B2U9Y5, SYS_RALPJ  ;  Q8XWY3, SYS_RALSO  ;  B3PXU3, SYS_RHIE6  ;
DR   Q2K967, SYS_RHIEC  ;  Q1MHM2, SYS_RHIL3  ;  Q98LC8, SYS_RHILO  ;
DR   B5ZMG0, SYS_RHILW  ;  Q92Q22, SYS_RHIME  ;  C3MBU2, SYS_RHISN  ;
DR   Q7UXX6, SYS_RHOBA  ;  B6ISM1, SYS_RHOCS  ;  Q21TF1, SYS_RHOFD  ;
DR   C1B914, SYS_RHOOB  ;  Q2IWG6, SYS_RHOP2  ;  Q07N47, SYS_RHOP5  ;
DR   Q6N5X5, SYS_RHOPA  ;  Q214W8, SYS_RHOPB  ;  Q136H4, SYS_RHOPS  ;
DR   B3Q6H9, SYS_RHOPT  ;  Q2RTH5, SYS_RHORT  ;  Q0S9E8, SYS_RHOSR  ;
DR   C3PLR3, SYS_RICAE  ;  A8GPX3, SYS_RICAH  ;  A8GY58, SYS_RICB8  ;
DR   Q1RKF4, SYS_RICBR  ;  A8EZY3, SYS_RICCK  ;  Q92GA7, SYS_RICCN  ;
DR   Q4UK35, SYS_RICFE  ;  A8F2S3, SYS_RICM5  ;  Q9ZCG5, SYS_RICPR  ;
DR   C4K208, SYS_RICPU  ;  B0BV96, SYS_RICRO  ;  A8GTQ7, SYS_RICRS  ;
DR   Q68VW6, SYS_RICTY  ;  A7NJB8, SYS_ROSCS  ;  Q166J5, SYS_ROSDO  ;
DR   A5UYX1, SYS_ROSS1  ;  Q1AX26, SYS_RUBXD  ;  Q21K22, SYS_SACD2  ;
DR   B5F146, SYS_SALA4  ;  A9MHZ1, SYS_SALAR  ;  Q57R38, SYS_SALCH  ;
DR   B5FQ36, SYS_SALDC  ;  B5QYP4, SYS_SALEP  ;  B5R8I1, SYS_SALG2  ;
DR   B4TD24, SYS_SALHS  ;  B4T128, SYS_SALNS  ;  Q5PGI6, SYS_SALPA  ;
DR   A9N7X6, SYS_SALPB  ;  C0PXT0, SYS_SALPC  ;  B5BBR2, SYS_SALPK  ;
DR   Q2S1G4, SYS_SALRD  ;  B4TRS5, SYS_SALSV  ;  P67564, SYS_SALTI  ;
DR   P67563, SYS_SALTY  ;  A8GCF0, SYS_SERP5  ;  A1S6H5, SYS_SHEAM  ;
DR   B8EET7, SYS_SHEB2  ;  A3D4J4, SYS_SHEB5  ;  A6WNG1, SYS_SHEB8  ;
DR   A9L269, SYS_SHEB9  ;  Q12NE5, SYS_SHEDO  ;  Q083B6, SYS_SHEFN  ;
DR   B0TUP4, SYS_SHEHH  ;  A3QEI8, SYS_SHELP  ;  Q8EEQ9, SYS_SHEON  ;
DR   A8H4R2, SYS_SHEPA  ;  A4Y6Z5, SYS_SHEPC  ;  B8CP82, SYS_SHEPW  ;
DR   A0KWW5, SYS_SHESA  ;  A8FV67, SYS_SHESH  ;  Q0HIS7, SYS_SHESM  ;
DR   Q0HV57, SYS_SHESR  ;  A1RJJ4, SYS_SHESW  ;  B1KG49, SYS_SHEWM  ;
DR   B2TUI5, SYS_SHIB3  ;  Q323L0, SYS_SHIBS  ;  Q32E12, SYS_SHIDS  ;
DR   Q0T8M9, SYS_SHIF8  ;  P0A8L4, SYS_SHIFL  ;  Q3Z3M7, SYS_SHISS  ;
DR   Q5LR07, SYS_SILPO  ;  Q1GHY9, SYS_SILST  ;  A6U8N8, SYS_SINMW  ;
DR   Q2NTY9, SYS_SODGM  ;  Q024V4, SYS_SOLUE  ;  A9FM88, SYS_SORC5  ;
DR   Q1GV79, SYS_SPHAL  ;  A5V3Y9, SYS_SPHWW  ;  A7WWP0, SYS_STAA1  ;
DR   A6TXF9, SYS_STAA2  ;  Q2FKP7, SYS_STAA3  ;  P95689, SYS_STAA8  ;
DR   A5INQ0, SYS_STAA9  ;  Q2YUR2, SYS_STAAB  ;  Q5HJY7, SYS_STAAC  ;
DR   A6QD48, SYS_STAAE  ;  P61083, SYS_STAAM  ;  P99178, SYS_STAAN  ;
DR   Q6GKT6, SYS_STAAR  ;  Q6GD81, SYS_STAAS  ;  A8YYT2, SYS_STAAT  ;
DR   Q8NYY2, SYS_STAAW  ;  B9DPW5, SYS_STACT  ;  Q5HK07, SYS_STAEQ  ;
DR   Q8CU95, SYS_STAES  ;  Q4LAK8, SYS_STAHJ  ;  A3DP85, SYS_STAMF  ;
DR   Q4A172, SYS_STAS1  ;  Q3K326, SYS_STRA1  ;  P67565, SYS_STRA3  ;
DR   P67566, SYS_STRA5  ;  Q9ZBX1, SYS_STRCO  ;  C0M858, SYS_STRE4  ;
DR   B4U1C3, SYS_STREM  ;  A8AYV0, SYS_STRGC  ;  B1VP80, SYS_STRGG  ;
DR   B4SP40, SYS_STRM5  ;  B2FKE4, SYS_STRMK  ;  Q8DSB7, SYS_STRMU  ;
DR   Q99YE2, SYS_STRP1  ;  Q04M63, SYS_STRP2  ;  P0DG56, SYS_STRP3  ;
DR   B5E7F2, SYS_STRP4  ;  Q5XAF1, SYS_STRP6  ;  C1C5E8, SYS_STRP7  ;
DR   Q8NZN7, SYS_STRP8  ;  Q1JA99, SYS_STRPB  ;  Q1JKF1, SYS_STRPC  ;
DR   Q1JFE4, SYS_STRPD  ;  Q1J594, SYS_STRPF  ;  A2RCY1, SYS_STRPG  ;
DR   B1I9K5, SYS_STRPI  ;  B8ZLH8, SYS_STRPJ  ;  Q48RS8, SYS_STRPM  ;
DR   Q97SG0, SYS_STRPN  ;  P0DG57, SYS_STRPQ  ;  B5XHX4, SYS_STRPZ  ;
DR   Q8DR22, SYS_STRR6  ;  C0ME07, SYS_STRS7  ;  A3CQ45, SYS_STRSV  ;
DR   Q03MA3, SYS_STRTD  ;  B9DVD8, SYS_STRU0  ;  C1CCH7, SYS_STRZJ  ;
DR   C1CIR2, SYS_STRZP  ;  C1CPS1, SYS_STRZT  ;  Q4J8I4, SYS_SULAC  ;
DR   Q30PY7, SYS_SULDN  ;  C3N6A0, SYS_SULIA  ;  C4KHR4, SYS_SULIK  ;
DR   C3MQH9, SYS_SULIL  ;  C3MW57, SYS_SULIM  ;  C3NGY7, SYS_SULIN  ;
DR   C3NEQ7, SYS_SULIY  ;  A6QBP2, SYS_SULNB  ;  O33780, SYS_SULSO  ;
DR   B2VA33, SYS_SULSY  ;  Q970Y4, SYS_SULTO  ;  Q67TJ8, SYS_SYMTH  ;
DR   Q8GMR7, SYS_SYNE7  ;  A0LI63, SYS_SYNFM  ;  Q2JXL1, SYS_SYNJA  ;
DR   Q2JKN4, SYS_SYNJB  ;  B1XJM0, SYS_SYNP2  ;  A5GN16, SYS_SYNPW  ;
DR   Q7U518, SYS_SYNPX  ;  A5GRE1, SYS_SYNR3  ;  Q0I8C9, SYS_SYNS3  ;
DR   Q3AV47, SYS_SYNS9  ;  Q3AM35, SYS_SYNSC  ;  Q0B0Y5, SYS_SYNWW  ;
DR   P73201, SYS_SYNY3  ;  C5BIK4, SYS_TERTT  ;  B7IFW4, SYS_THEAB  ;
DR   Q9HKX5, SYS_THEAC  ;  Q8DIN0, SYS_THEEB  ;  Q47TZ5, SYS_THEFY  ;
DR   C5A226, SYS_THEGJ  ;  A8F3R6, SYS_THELT  ;  A6LJM6, SYS_THEM4  ;
DR   Q9X199, SYS_THEMA  ;  B9K8V5, SYS_THENN  ;  B1Y9Y4, SYS_THENV  ;
DR   B6YWW5, SYS_THEON  ;  A5IMJ4, SYS_THEP1  ;  B0KAI8, SYS_THEP3  ;
DR   B0K0Z5, SYS_THEPX  ;  B9L131, SYS_THERP  ;  C6A4A3, SYS_THESM  ;
DR   B1LBU6, SYS_THESQ  ;  P34945, SYS_THET2  ;  Q5SJX7, SYS_THET8  ;
DR   Q8RDJ5, SYS_THETN  ;  Q979Z3, SYS_THEVO  ;  B5YGU2, SYS_THEYD  ;
DR   Q31HK9, SYS_THICR  ;  Q3SJH9, SYS_THIDA  ;  B8GQ80, SYS_THISH  ;
DR   C4L937, SYS_TOLAT  ;  Q73KB2, SYS_TREDE  ;  O83653, SYS_TREPA  ;
DR   B2S3N6, SYS_TREPS  ;  Q10YR2, SYS_TRIEI  ;  Q83HA1, SYS_TROW8  ;
DR   Q83FJ7, SYS_TROWT  ;  Q0W8S5, SYS_UNCMA  ;  B1GZ25, SYS_UNCTG  ;
DR   B1AI95, SYS_UREP2  ;  Q9PR38, SYS_UREPA  ;  B5ZAT6, SYS_UREU1  ;
DR   C5CWN5, SYS_VARPS  ;  A1WP10, SYS_VEREI  ;  A5CVL9, SYS_VESOH  ;
DR   A5F2H1, SYS_VIBC3  ;  Q9KSZ6, SYS_VIBCH  ;  C3LU07, SYS_VIBCM  ;
DR   Q5E6E3, SYS_VIBF1  ;  B5FCK7, SYS_VIBFM  ;  A7MSW8, SYS_VIBHB  ;
DR   Q87QP1, SYS_VIBPA  ;  B7VH19, SYS_VIBSL  ;  Q8D8M6, SYS_VIBVU  ;
DR   Q7MLV2, SYS_VIBVY  ;  Q8D265, SYS_WIGBR  ;  Q73IW5, SYS_WOLPM  ;
DR   B3CQ06, SYS_WOLPP  ;  Q7M9J5, SYS_WOLSU  ;  Q5GSH2, SYS_WOLTR  ;
DR   Q8PLY2, SYS_XANAC  ;  Q3BUY8, SYS_XANC5  ;  Q4UTD4, SYS_XANC8  ;
DR   B0RUV8, SYS_XANCB  ;  Q8PA92, SYS_XANCP  ;  Q2P3Y4, SYS_XANOM  ;
DR   A7INN1, SYS_XANP2  ;  B2I631, SYS_XYLF2  ;  Q9PB58, SYS_XYLFA  ;
DR   B0U3G5, SYS_XYLFM  ;  Q87BX8, SYS_XYLFT  ;  A1JMG0, SYS_YERE8  ;
DR   A7FJY0, SYS_YERP3  ;  Q1CA85, SYS_YERPA  ;  B2KA12, SYS_YERPB  ;
DR   Q8ZGC4, SYS_YERPE  ;  A9R5V2, SYS_YERPG  ;  Q1CGF1, SYS_YERPN  ;
DR   A4TN29, SYS_YERPP  ;  Q66CJ9, SYS_YERPS  ;  B1JRF0, SYS_YERPY  ;
DR   Q5NNV0, SYS_ZYMMO  ;
//
ID   6.1.1.12
DE   Aspartate--tRNA ligase.
AN   Aspartic acid translase.
AN   Aspartyl-tRNA synthetase.
CA   ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp).
PR   PROSITE; PDOC00363;
DR   Q8DSG3, SYD1_STRMU ;  Q2LPW5, SYD1_SYNAS ;  Q8DRV9, SYD2_STRMU ;
DR   Q2LTE0, SYD2_SYNAS ;  Q75JQ1, SYDC1_DICDI;  Q559M9, SYDC2_DICDI;
DR   Q3SYZ4, SYDC_BOVIN ;  Q03577, SYDC_CAEEL ;  Q8SRQ8, SYDC_ENCCU ;
DR   B7XHQ4, SYDC_ENTBH ;  P14868, SYDC_HUMAN ;  Q922B2, SYDC_MOUSE ;
DR   Q5R9I5, SYDC_PONAB ;  P15178, SYDC_RAT   ;  O74407, SYDC_SCHPO ;
DR   P04802, SYDC_YEAST ;  A6QPU5, SYDM_BOVIN ;  Q55C99, SYDM_DICDI ;
DR   Q6PI48, SYDM_HUMAN ;  Q8BIP0, SYDM_MOUSE ;  Q3KRD0, SYDM_RAT   ;
DR   O94242, SYDM_SCHPO ;  P15179, SYDM_YEAST ;  B0CF01, SYD_ACAM1  ;
DR   A1TT99, SYD_ACIAC  ;  Q6FEH6, SYD_ACIAD  ;  B7GWN1, SYD_ACIB3  ;
DR   B7I8M5, SYD_ACIB5  ;  B2HYL7, SYD_ACIBC  ;  B0VRC7, SYD_ACIBS  ;
DR   A3M8Q6, SYD_ACIBT  ;  B0V550, SYD_ACIBY  ;  A0LUJ6, SYD_ACIC1  ;
DR   C1FAE8, SYD_ACIC5  ;  A5G126, SYD_ACICJ  ;  B9ME28, SYD_ACIET  ;
DR   B7J3F7, SYD_ACIF2  ;  B5EJL3, SYD_ACIF5  ;  A1W4E1, SYD_ACISJ  ;
DR   A3N1F3, SYD_ACTP2  ;  B3GY37, SYD_ACTP7  ;  B0BQ90, SYD_ACTPJ  ;
DR   A6VQA9, SYD_ACTSZ  ;  Q9Y9U7, SYD_AERPE  ;  A4SPN5, SYD_AERS4  ;
DR   B9JCV9, SYD_AGRRK  ;  Q8UG87, SYD_AGRT5  ;  B9JV61, SYD_AGRVS  ;
DR   Q0VRK1, SYD_ALCBS  ;  Q0A582, SYD_ALHEH  ;  B6EGJ1, SYD_ALISL  ;
DR   B4RXE7, SYD_ALTMD  ;  B3EUH5, SYD_AMOA5  ;  B8JH60, SYD_ANAD2  ;
DR   Q2IKX7, SYD_ANADE  ;  B9KHS0, SYD_ANAMF  ;  Q2GLD8, SYD_ANAPZ  ;
DR   B4UIE3, SYD_ANASK  ;  Q3MGL3, SYD_ANAVT  ;  B7GFR1, SYD_ANOFW  ;
DR   O67589, SYD_AQUAE  ;  A8ESW7, SYD_ARCB4  ;  O29342, SYD_ARCFU  ;
DR   Q5P280, SYD_AROAE  ;  B8H9C7, SYD_ARTCA  ;  A0JXA1, SYD_ARTS2  ;
DR   Q2NIN3, SYD_AYWBP  ;  A8IFX1, SYD_AZOC5  ;  B6YS49, SYD_AZOPC  ;
DR   A1KAJ9, SYD_AZOSB  ;  C1DRG2, SYD_AZOVD  ;  A7Z750, SYD_BACA2  ;
DR   C3P990, SYD_BACAA  ;  C3L608, SYD_BACAC  ;  A0RJ11, SYD_BACAH  ;
DR   Q81LI7, SYD_BACAN  ;  B7JPY8, SYD_BACC0  ;  Q730D1, SYD_BACC1  ;
DR   B7IIR4, SYD_BACC2  ;  C1ESU7, SYD_BACC3  ;  B7HE37, SYD_BACC4  ;
DR   B7HQG0, SYD_BACC7  ;  A7GT84, SYD_BACCN  ;  B9IYX5, SYD_BACCQ  ;
DR   Q817X8, SYD_BACCR  ;  Q634E3, SYD_BACCZ  ;  Q5LCK2, SYD_BACFN  ;
DR   Q64TQ1, SYD_BACFR  ;  Q9KDG1, SYD_BACHD  ;  Q6HDC3, SYD_BACHK  ;
DR   Q65GR4, SYD_BACLD  ;  Q5WHP3, SYD_BACSK  ;  O32038, SYD_BACSU  ;
DR   Q8A9E3, SYD_BACTN  ;  A6L585, SYD_BACV8  ;  A9VIM8, SYD_BACWK  ;
DR   A1UT52, SYD_BARBK  ;  Q6G330, SYD_BARHE  ;  Q6FZI4, SYD_BARQU  ;
DR   A9IVI2, SYD_BART1  ;  Q1LTF0, SYD_BAUCH  ;  Q6MI59, SYD_BDEBA  ;
DR   B2IKA4, SYD_BEII9  ;  C5C5S1, SYD_BEUC1  ;  B3DPM0, SYD_BIFLD  ;
DR   Q8G863, SYD_BIFLO  ;  B7GPT0, SYD_BIFLS  ;  Q7VQX8, SYD_BLOFL  ;
DR   Q492L1, SYD_BLOPB  ;  Q2L1K6, SYD_BORA1  ;  Q0SN63, SYD_BORAP  ;
DR   Q7WR42, SYD_BORBR  ;  O51402, SYD_BORBU  ;  B7J213, SYD_BORBZ  ;
DR   B5RM04, SYD_BORDL  ;  Q661H4, SYD_BORGA  ;  B2S0F0, SYD_BORHD  ;
DR   Q7W275, SYD_BORPA  ;  A9IHE2, SYD_BORPD  ;  Q7W001, SYD_BORPE  ;
DR   B5RRQ0, SYD_BORRA  ;  A1QZN3, SYD_BORT9  ;  C0R2C9, SYD_BRAHW  ;
DR   Q89MP9, SYD_BRAJA  ;  A5EIE6, SYD_BRASB  ;  A4YTC4, SYD_BRASO  ;
DR   B2S501, SYD_BRUA1  ;  Q2YNA7, SYD_BRUA2  ;  Q57DZ8, SYD_BRUAB  ;
DR   A9MAD3, SYD_BRUC2  ;  C0RI89, SYD_BRUMB  ;  P67012, SYD_BRUME  ;
DR   A5VPT5, SYD_BRUO2  ;  B0CL77, SYD_BRUSI  ;  P67013, SYD_BRUSU  ;
DR   B8D9A6, SYD_BUCA5  ;  P57401, SYD_BUCAI  ;  P81432, SYD_BUCAP  ;
DR   B8D7K8, SYD_BUCAT  ;  P59422, SYD_BUCBP  ;  B1YWF2, SYD_BURA4  ;
DR   Q1BTP1, SYD_BURCA  ;  B1JYI9, SYD_BURCC  ;  A0KAE8, SYD_BURCH  ;
DR   B4EBD1, SYD_BURCJ  ;  Q0BBZ1, SYD_BURCM  ;  A9AFC7, SYD_BURM1  ;
DR   A3MNU6, SYD_BURM7  ;  A2S8L9, SYD_BURM9  ;  Q62MP0, SYD_BURMA  ;
DR   A1V745, SYD_BURMS  ;  A3NRK2, SYD_BURP0  ;  Q3JVY8, SYD_BURP1  ;
DR   A3N5V6, SYD_BURP6  ;  B2JCV5, SYD_BURP8  ;  B2SX42, SYD_BURPP  ;
DR   Q63X93, SYD_BURPS  ;  Q39D20, SYD_BURS3  ;  Q2T132, SYD_BURTA  ;
DR   A4JHR9, SYD_BURVG  ;  Q145N3, SYD_BURXL  ;  A7ZEH3, SYD_CAMC1  ;
DR   A0RQ71, SYD_CAMFF  ;  A7I058, SYD_CAMHC  ;  A8FL61, SYD_CAMJ8  ;
DR   A7H4H2, SYD_CAMJD  ;  Q9PHM7, SYD_CAMJE  ;  A1VZ00, SYD_CAMJJ  ;
DR   Q5HVD1, SYD_CAMJR  ;  Q3AA17, SYD_CARHZ  ;  Q9A734, SYD_CAUCR  ;
DR   B0SWQ6, SYD_CAUSK  ;  B3PB55, SYD_CELJU  ;  A9WGJ7, SYD_CHLAA  ;
DR   Q5L734, SYD_CHLAB  ;  B8G6W9, SYD_CHLAD  ;  Q3AS30, SYD_CHLCH  ;
DR   Q46175, SYD_CHLCV  ;  B3EDE5, SYD_CHLL2  ;  Q9PJK0, SYD_CHLMU  ;
DR   B3QP90, SYD_CHLP8  ;  B3EQ26, SYD_CHLPB  ;  A1BGZ4, SYD_CHLPD  ;
DR   Q9Z7P2, SYD_CHLPN  ;  B9LJ78, SYD_CHLSY  ;  B0B8B6, SYD_CHLT2  ;
DR   Q3KLF5, SYD_CHLTA  ;  B0B9Z5, SYD_CHLTB  ;  Q8KCT7, SYD_CHLTE  ;
DR   O84546, SYD_CHLTR  ;  Q1QWG2, SYD_CHRSD  ;  Q7NRP0, SYD_CHRVO  ;
DR   A8AFH5, SYD_CITK8  ;  Q97GU6, SYD_CLOAB  ;  A7FY03, SYD_CLOB1  ;
DR   C3KTB6, SYD_CLOB6  ;  A6LTP1, SYD_CLOB8  ;  B2V351, SYD_CLOBA  ;
DR   B2TN05, SYD_CLOBB  ;  A5I6D5, SYD_CLOBH  ;  C1FKE5, SYD_CLOBJ  ;
DR   B1IMD7, SYD_CLOBK  ;  A7GHS2, SYD_CLOBL  ;  B1L096, SYD_CLOBM  ;
DR   B8I3F1, SYD_CLOCE  ;  B9E5P2, SYD_CLOK1  ;  A5N1Y8, SYD_CLOK5  ;
DR   A0PZX0, SYD_CLONN  ;  Q0TP28, SYD_CLOP1  ;  Q8XJ28, SYD_CLOPE  ;
DR   A9KIA6, SYD_CLOPH  ;  Q0SRP8, SYD_CLOPS  ;  Q892B2, SYD_CLOTE  ;
DR   Q483C7, SYD_COLP3  ;  C3PGN5, SYD_CORA7  ;  Q6NGZ4, SYD_CORDI  ;
DR   Q8FT19, SYD_COREF  ;  A4QEL0, SYD_CORGB  ;  Q8NQ19, SYD_CORGL  ;
DR   Q4JVF2, SYD_CORJK  ;  C4LIW2, SYD_CORK4  ;  B1VDL1, SYD_CORU7  ;
DR   A9KF44, SYD_COXBN  ;  A9N999, SYD_COXBR  ;  Q83BE5, SYD_COXBU  ;
DR   Q0KEG8, SYD_CUPNH  ;  Q475W2, SYD_CUPPJ  ;  B2AH15, SYD_CUPTR  ;
DR   B1WRQ9, SYD_CYAA5  ;  B8HXQ8, SYD_CYAP4  ;  B7KB89, SYD_CYAP7  ;
DR   B7JX16, SYD_CYAP8  ;  Q11YW2, SYD_CYTH3  ;  Q47IE0, SYD_DECAR  ;
DR   Q3Z8K0, SYD_DEHE1  ;  A5FRE3, SYD_DEHSB  ;  Q3ZX84, SYD_DEHSC  ;
DR   C1CV34, SYD_DEIDV  ;  Q1IZB4, SYD_DEIGD  ;  Q9RUN7, SYD_DEIRA  ;
DR   A9BP37, SYD_DELAS  ;  B8FKS6, SYD_DESAA  ;  C0QFI1, SYD_DESAH  ;
DR   Q317R3, SYD_DESDG  ;  A8ZUR7, SYD_DESOH  ;  Q6AQS4, SYD_DESPS  ;
DR   A4J2J2, SYD_DESRM  ;  Q725Q7, SYD_DESVH  ;  B5YDT0, SYD_DICT6  ;
DR   B8E1C0, SYD_DICTD  ;  A8LI32, SYD_DINSH  ;  A7ZMZ0, SYD_ECO24  ;
DR   B7USP3, SYD_ECO27  ;  B7MBS5, SYD_ECO45  ;  B7L7R9, SYD_ECO55  ;
DR   Q8XCI7, SYD_ECO57  ;  B5YR11, SYD_ECO5E  ;  B7NS52, SYD_ECO7I  ;
DR   B7MVZ7, SYD_ECO81  ;  B7M2F7, SYD_ECO8A  ;  C4ZQF0, SYD_ECOBW  ;
DR   B1XHD4, SYD_ECODH  ;  A8A166, SYD_ECOHS  ;  A1AC27, SYD_ECOK1  ;
DR   Q0TGW6, SYD_ECOL5  ;  Q8FGQ9, SYD_ECOL6  ;  B1J0M2, SYD_ECOLC  ;
DR   P21889, SYD_ECOLI  ;  B7NBL7, SYD_ECOLU  ;  B6IBU5, SYD_ECOSE  ;
DR   B1LD05, SYD_ECOSM  ;  Q1RAR8, SYD_ECOUT  ;  C5B9S7, SYD_EDWI9  ;
DR   Q3YRF1, SYD_EHRCJ  ;  Q2GHC9, SYD_EHRCR  ;  Q5FG09, SYD_EHRRG  ;
DR   Q5HAL5, SYD_EHRRW  ;  B2KBB9, SYD_ELUMP  ;  A4WBM3, SYD_ENT38  ;
DR   Q833I2, SYD_ENTFA  ;  A7MEB6, SYD_ENTS8  ;  Q6D497, SYD_ERWCT  ;
DR   B2VJ90, SYD_ERWT9  ;  Q2NBQ6, SYD_ERYLH  ;  B7LPH8, SYD_ESCF3  ;
DR   C4ZI12, SYD_EUBR3  ;  B1YJF7, SYD_EXIS2  ;  C4L535, SYD_EXISA  ;
DR   A7HME4, SYD_FERNB  ;  A5FKJ2, SYD_FLAJ1  ;  A6GWB6, SYD_FLAPJ  ;
DR   B0TW08, SYD_FRAP2  ;  A7N949, SYD_FRATF  ;  Q2A622, SYD_FRATH  ;
DR   Q0BPA2, SYD_FRATO  ;  Q5NIQ4, SYD_FRATT  ;  A4J0C7, SYD_FRATW  ;
DR   Q8RGJ4, SYD_FUSNN  ;  B5EIV1, SYD_GEOBB  ;  Q5KWS9, SYD_GEOKA  ;
DR   Q39VY3, SYD_GEOMG  ;  B9M1C9, SYD_GEOSF  ;  Q74D56, SYD_GEOSL  ;
DR   C6E3W7, SYD_GEOSM  ;  C5D509, SYD_GEOSW  ;  A5G3L5, SYD_GEOUR  ;
DR   Q7NJA4, SYD_GLOVI  ;  Q5FQ60, SYD_GLUOX  ;  Q7VNF0, SYD_HAEDU  ;
DR   Q4QNM1, SYD_HAEI8  ;  A5UAG7, SYD_HAEIE  ;  A5UGD3, SYD_HAEIG  ;
DR   P43817, SYD_HAEIN  ;  B8F789, SYD_HAEPS  ;  Q0I3S3, SYD_HAES1  ;
DR   B0USU0, SYD_HAES2  ;  Q2SCK8, SYD_HAHCH  ;  Q5V1N2, SYD_HALMA  ;
DR   B8CXE5, SYD_HALOH  ;  O07683, SYD_HALSA  ;  O24822, SYD_HALVO  ;
DR   Q18KP5, SYD_HALWD  ;  C4K4U5, SYD_HAMD5  ;  Q17XK9, SYD_HELAH  ;
DR   Q7VF76, SYD_HELHP  ;  B0TF89, SYD_HELMI  ;  B6JLK1, SYD_HELP2  ;
DR   B5Z6Y8, SYD_HELPG  ;  Q1CTQ7, SYD_HELPH  ;  Q9ZLL9, SYD_HELPJ  ;
DR   B2UTL0, SYD_HELPS  ;  P56459, SYD_HELPY  ;  A9B392, SYD_HERA2  ;
DR   A4G8X1, SYD_HERAR  ;  B4U7P3, SYD_HYDS0  ;  Q0BZZ1, SYD_HYPNA  ;
DR   Q5QYV2, SYD_IDILO  ;  Q28MH9, SYD_JANSC  ;  A6WCG5, SYD_KINRD  ;
DR   B5XQ00, SYD_KLEP3  ;  A6TB35, SYD_KLEP7  ;  Q5FKI4, SYD_LACAC  ;
DR   Q038S1, SYD_LACC3  ;  B3WEM2, SYD_LACCB  ;  B2GBY7, SYD_LACF3  ;
DR   Q74IX4, SYD_LACJO  ;  Q9CE80, SYD_LACLA  ;  A2RN94, SYD_LACLM  ;
DR   Q02WJ0, SYD_LACLS  ;  Q88VQ8, SYD_LACPL  ;  A5VJG4, SYD_LACRD  ;
DR   B2G6X9, SYD_LACRJ  ;  Q1WTU9, SYD_LACS1  ;  Q38XB6, SYD_LACSS  ;
DR   C1DB91, SYD_LARHH  ;  Q5X586, SYD_LEGPA  ;  A5IBW8, SYD_LEGPC  ;
DR   Q5ZVG2, SYD_LEGPH  ;  Q5WWA3, SYD_LEGPL  ;  B0SB35, SYD_LEPBA  ;
DR   B0SSV7, SYD_LEPBP  ;  B1XWR8, SYD_LEPCP  ;  Q72QK5, SYD_LEPIC  ;
DR   Q8F5K1, SYD_LEPIN  ;  B1MY98, SYD_LEUCK  ;  Q03WL7, SYD_LEUMM  ;
DR   Q92BJ4, SYD_LISIN  ;  C1KVG6, SYD_LISMC  ;  Q71ZF1, SYD_LISMF  ;
DR   B8DHM9, SYD_LISMH  ;  Q8Y709, SYD_LISMO  ;  A0AIW8, SYD_LISW6  ;
DR   B1HV71, SYD_LYSSC  ;  B9E706, SYD_MACCJ  ;  Q2W3D5, SYD_MAGSA  ;
DR   A0L667, SYD_MAGSM  ;  Q65UP5, SYD_MANSM  ;  A1U1C2, SYD_MARAV  ;
DR   Q0AQ87, SYD_MARMM  ;  A6VXD0, SYD_MARMS  ;  Q6F1A0, SYD_MESFL  ;
DR   Q11JA7, SYD_MESSB  ;  A6USZ9, SYD_META3  ;  Q8TQ68, SYD_METAC  ;
DR   Q466Y5, SYD_METBF  ;  Q12XU7, SYD_METBU  ;  B7KN33, SYD_METC4  ;
DR   Q607I4, SYD_METCA  ;  Q1GYN8, SYD_METFK  ;  Q2FRU5, SYD_METHJ  ;
DR   B3DX01, SYD_METI4  ;  Q58950, SYD_METJA  ;  Q8TXG4, SYD_METKA  ;
DR   A2SPG1, SYD_METLZ  ;  A4G0V5, SYD_METM5  ;  A9A945, SYD_METM6  ;
DR   A6VHK5, SYD_METM7  ;  Q8Q0R2, SYD_METMA  ;  A3CXH4, SYD_METMJ  ;
DR   Q6LWU0, SYD_METMP  ;  B8IUT2, SYD_METNO  ;  B1ZFX6, SYD_METPB  ;
DR   A2SEP2, SYD_METPP  ;  B0UI66, SYD_METS4  ;  B8EN55, SYD_METSB  ;
DR   Q2NHT0, SYD_METST  ;  O26328, SYD_METTH  ;  A6UQQ8, SYD_METVS  ;
DR   B0JNW9, SYD_MICAN  ;  C5CCH2, SYD_MICLC  ;  Q2RHW1, SYD_MOOTA  ;
DR   A0QI91, SYD_MYCA1  ;  B1MCH3, SYD_MYCA9  ;  Q7TYA6, SYD_MYCBO  ;
DR   Q48979, SYD_MYCCT  ;  P47282, SYD_MYCGE  ;  A4TBU4, SYD_MYCGI  ;
DR   B8ZUJ3, SYD_MYCLB  ;  P36429, SYD_MYCLE  ;  Q6MTR3, SYD_MYCMS  ;
DR   Q741M7, SYD_MYCPA  ;  Q8EWB7, SYD_MYCPE  ;  P75068, SYD_MYCPN  ;
DR   A0QWN3, SYD_MYCS2  ;  A3PZ05, SYD_MYCSJ  ;  A1UFE5, SYD_MYCSK  ;
DR   Q50649, SYD_MYCTU  ;  Q3IT59, SYD_NATPD  ;  B2A2G0, SYD_NATTJ  ;
DR   B4RPA1, SYD_NEIG2  ;  A9M257, SYD_NEIM0  ;  Q9JT23, SYD_NEIMA  ;
DR   Q9K0U5, SYD_NEIMB  ;  A1KVG2, SYD_NEIMF  ;  Q0AIE4, SYD_NITEC  ;
DR   Q82SQ5, SYD_NITEU  ;  Q1QLI9, SYD_NITHX  ;  Q2YBG1, SYD_NITMU  ;
DR   Q3JEB6, SYD_NITOC  ;  Q3SS92, SYD_NITWN  ;  Q5YTJ4, SYD_NOCFA  ;
DR   A1SJB8, SYD_NOCSJ  ;  B2J116, SYD_NOSP7  ;  Q8YUB6, SYD_NOSS1  ;
DR   Q2G8P1, SYD_NOVAD  ;  Q8EPS0, SYD_OCEIH  ;  A6X200, SYD_OCHA4  ;
DR   B6JGJ7, SYD_OLICO  ;  Q6YR88, SYD_ONYPE  ;  B1ZSW8, SYD_OPITP  ;
DR   A5CC91, SYD_ORITB  ;  B3CV53, SYD_ORITI  ;  A6LBU6, SYD_PARD8  ;
DR   A1B431, SYD_PARDP  ;  A7HYC4, SYD_PARL1  ;  Q6ME91, SYD_PARUW  ;
DR   P57895, SYD_PASMU  ;  C6DFE7, SYD_PECCP  ;  Q03F52, SYD_PEDPA  ;
DR   Q3A5R7, SYD_PELCD  ;  Q3B3A1, SYD_PELLD  ;  B4SAH1, SYD_PELPB  ;
DR   A5D3E3, SYD_PELTS  ;  Q4FMP8, SYD_PELUB  ;  C0QT74, SYD_PERMH  ;
DR   B4RCT1, SYD_PHEZH  ;  Q7MB41, SYD_PHOLL  ;  Q6LT53, SYD_PHOPR  ;
DR   Q6KZQ3, SYD_PICTO  ;  B2RHE0, SYD_PORG3  ;  Q7MXM0, SYD_PORGI  ;
DR   B4S8V2, SYD_PROA2  ;  Q6A8J1, SYD_PROAC  ;  A3PFH7, SYD_PROM0  ;
DR   A8G7J3, SYD_PROM2  ;  A2CDX5, SYD_PROM3  ;  A9BDD8, SYD_PROM4  ;
DR   A2BZ75, SYD_PROM5  ;  Q317V3, SYD_PROM9  ;  Q7V9I1, SYD_PROMA  ;
DR   B4ETP3, SYD_PROMH  ;  Q7V3X1, SYD_PROMM  ;  Q7UZH8, SYD_PROMP  ;
DR   A2BTS0, SYD_PROMS  ;  Q46I98, SYD_PROMT  ;  A4SF07, SYD_PROVI  ;
DR   Q48FC1, SYD_PSE14  ;  Q15RN2, SYD_PSEA6  ;  B7UXW9, SYD_PSEA8  ;
DR   Q02IC5, SYD_PSEAB  ;  Q51422, SYD_PSEAE  ;  Q1I6E5, SYD_PSEE4  ;
DR   Q4K7D5, SYD_PSEF5  ;  C3JYT1, SYD_PSEFS  ;  Q3IIN7, SYD_PSEHT  ;
DR   A4XRR7, SYD_PSEMY  ;  A5VZU3, SYD_PSEP1  ;  Q3K7V6, SYD_PSEPF  ;
DR   B0KTJ6, SYD_PSEPG  ;  Q88NJ4, SYD_PSEPK  ;  B1JD74, SYD_PSEPW  ;
DR   Q87Y31, SYD_PSESM  ;  Q4ZWL5, SYD_PSEU2  ;  Q4FSF4, SYD_PSYA2  ;
DR   Q1QBI9, SYD_PSYCK  ;  A1SST6, SYD_PSYIN  ;  A5WE50, SYD_PSYWF  ;
DR   Q9V036, SYD_PYRAB  ;  Q8ZYM8, SYD_PYRAE  ;  Q8U2G6, SYD_PYRFU  ;
DR   O58776, SYD_PYRHO  ;  Q52428, SYD_PYRKO  ;  Q1LRG2, SYD_RALME  ;
DR   Q8Y270, SYD_RALSO  ;  Q1MIW0, SYD_RHIL3  ;  Q983E9, SYD_RHILO  ;
DR   B5ZX21, SYD_RHILW  ;  Q92QV4, SYD_RHIME  ;  C3M9G8, SYD_RHISN  ;
DR   Q7UFY6, SYD_RHOBA  ;  B6IN46, SYD_RHOCS  ;  C0ZZA3, SYD_RHOE4  ;
DR   Q21YX2, SYD_RHOFD  ;  C1B4G8, SYD_RHOOB  ;  Q2IX59, SYD_RHOP2  ;
DR   Q07LH5, SYD_RHOP5  ;  Q6N5D6, SYD_RHOPA  ;  Q215P7, SYD_RHOPB  ;
DR   Q135R5, SYD_RHOPS  ;  B3Q9Q1, SYD_RHOPT  ;  Q2RSM3, SYD_RHORT  ;
DR   A3PMK8, SYD_RHOS1  ;  Q3IZP1, SYD_RHOS4  ;  A4WPF7, SYD_RHOS5  ;
DR   B9KME7, SYD_RHOSK  ;  Q0S0P3, SYD_RHOSR  ;  C3PMI3, SYD_RICAE  ;
DR   A8GMB3, SYD_RICAH  ;  A8GXC5, SYD_RICB8  ;  Q1RJN4, SYD_RICBR  ;
DR   A8EXL4, SYD_RICCK  ;  Q92J82, SYD_RICCN  ;  Q4UKE2, SYD_RICFE  ;
DR   Q9ZE17, SYD_RICPR  ;  Q68XM3, SYD_RICTY  ;  A7NQH9, SYD_ROSCS  ;
DR   Q16B16, SYD_ROSDO  ;  A5UUR3, SYD_ROSS1  ;  Q1AWB4, SYD_RUBXD  ;
DR   A1AW56, SYD_RUTMC  ;  Q21MA4, SYD_SACD2  ;  A4FBC3, SYD_SACEN  ;
DR   B5F3I9, SYD_SALA4  ;  A8LXY1, SYD_SALAI  ;  A9MND2, SYD_SALAR  ;
DR   Q57N96, SYD_SALCH  ;  B5FSN0, SYD_SALDC  ;  B5R1V2, SYD_SALEP  ;
DR   B5R8D6, SYD_SALG2  ;  B4T7Z9, SYD_SALHS  ;  B4SVF1, SYD_SALNS  ;
DR   Q5PMZ6, SYD_SALPA  ;  A9MUB9, SYD_SALPB  ;  C0Q2E8, SYD_SALPC  ;
DR   B5BH54, SYD_SALPK  ;  Q2S158, SYD_SALRD  ;  B4TYS4, SYD_SALSV  ;
DR   Q8Z5W1, SYD_SALTI  ;  A4X5Y3, SYD_SALTO  ;  Q8ZNV2, SYD_SALTY  ;
DR   A8GFJ2, SYD_SERP5  ;  A1S6P2, SYD_SHEAM  ;  B8EA71, SYD_SHEB2  ;
DR   A3D477, SYD_SHEB5  ;  A6WNQ6, SYD_SHEB8  ;  A9L3I1, SYD_SHEB9  ;
DR   Q12N06, SYD_SHEDO  ;  Q081N5, SYD_SHEFN  ;  B0TSA3, SYD_SHEHH  ;
DR   A3QEP7, SYD_SHELP  ;  Q8EEE9, SYD_SHEON  ;  A8H549, SYD_SHEPA  ;
DR   A4Y6S5, SYD_SHEPC  ;  B8CNX7, SYD_SHEPW  ;  A0KWL5, SYD_SHESA  ;
DR   A8FUW6, SYD_SHESH  ;  Q0HIZ5, SYD_SHESM  ;  Q0HUY7, SYD_SHESR  ;
DR   A1RJQ6, SYD_SHESW  ;  B1KHG7, SYD_SHEWM  ;  B2TXL2, SYD_SHIB3  ;
DR   Q322D4, SYD_SHIBS  ;  Q32H95, SYD_SHIDS  ;  Q0T3U0, SYD_SHIF8  ;
DR   Q7UAE6, SYD_SHIFL  ;  Q3Z2M4, SYD_SHISS  ;  Q5LUX6, SYD_SILPO  ;
DR   Q1GIZ8, SYD_SILST  ;  A6U7M8, SYD_SINMW  ;  Q2NTJ3, SYD_SODGM  ;
DR   A7X344, SYD_STAA1  ;  A6U298, SYD_STAA2  ;  Q2FG97, SYD_STAA3  ;
DR   Q2FXU5, SYD_STAA8  ;  A5ITF4, SYD_STAA9  ;  Q2YT75, SYD_STAAB  ;
DR   Q5HFD3, SYD_STAAC  ;  A6QHH2, SYD_STAAE  ;  P67014, SYD_STAAM  ;
DR   P67015, SYD_STAAN  ;  Q6GG73, SYD_STAAR  ;  Q6G8T9, SYD_STAAS  ;
DR   A8Z2F7, SYD_STAAT  ;  P67016, SYD_STAAW  ;  B9DNF8, SYD_STACT  ;
DR   Q5HNS2, SYD_STAEQ  ;  Q8CS99, SYD_STAES  ;  Q4L6X5, SYD_STAHJ  ;
DR   Q49Y68, SYD_STAS1  ;  Q3JYL7, SYD_STRA1  ;  Q8E2Q7, SYD_STRA3  ;
DR   Q8DWV5, SYD_STRA5  ;  Q82F68, SYD_STRAW  ;  Q9F323, SYD_STRCO  ;
DR   C0MB16, SYD_STRE4  ;  B4U0K5, SYD_STREM  ;  B1VQW8, SYD_STRGG  ;
DR   B4ST40, SYD_STRM5  ;  B2FRP1, SYD_STRMK  ;  Q99XL0, SYD_STRP1  ;
DR   Q04I59, SYD_STRP2  ;  P0DG30, SYD_STRP3  ;  B5E3C1, SYD_STRP4  ;
DR   Q5X9E6, SYD_STRP6  ;  C1CAU1, SYD_STRP7  ;  Q8NZ20, SYD_STRP8  ;
DR   A2RGY0, SYD_STRPG  ;  B1I9S9, SYD_STRPI  ;  B8ZPN7, SYD_STRPJ  ;
DR   Q48QS8, SYD_STRPM  ;  Q97ND6, SYD_STRPN  ;  P0DG31, SYD_STRPQ  ;
DR   B2IN32, SYD_STRPS  ;  B5XJ82, SYD_STRPZ  ;  Q8CWN4, SYD_STRR6  ;
DR   A4W4L2, SYD_STRS2  ;  C0MGD3, SYD_STRS7  ;  A4VYB8, SYD_STRSY  ;
DR   Q5LXN1, SYD_STRT1  ;  Q5M283, SYD_STRT2  ;  Q03IB4, SYD_STRTD  ;
DR   B9DW80, SYD_STRU0  ;  C1CH44, SYD_STRZJ  ;  C1CN60, SYD_STRZP  ;
DR   C1CU16, SYD_STRZT  ;  Q30RL7, SYD_SULDN  ;  A6QAE8, SYD_SULNB  ;
DR   Q980V3, SYD_SULSO  ;  B2V713, SYD_SULSY  ;  Q976I3, SYD_SULTO  ;
DR   Q67LP0, SYD_SYMTH  ;  Q31NM6, SYD_SYNE7  ;  Q2JTZ2, SYD_SYNJA  ;
DR   Q2JMA8, SYD_SYNJB  ;  B1XNY9, SYD_SYNP2  ;  Q5N5I8, SYD_SYNP6  ;
DR   A5GPL9, SYD_SYNPW  ;  Q7U3K6, SYD_SYNPX  ;  A5GWT2, SYD_SYNR3  ;
DR   Q3AVS9, SYD_SYNS9  ;  Q3AGF9, SYD_SYNSC  ;  Q0AYS1, SYD_SYNWW  ;
DR   P73851, SYD_SYNY3  ;  C5BPP4, SYD_TERTT  ;  B7IE30, SYD_THEAB  ;
DR   Q9HJM1, SYD_THEAC  ;  Q8DJS8, SYD_THEEB  ;  Q47N50, SYD_THEFY  ;
DR   A8F7R7, SYD_THELT  ;  A6LNG3, SYD_THEM4  ;  Q9X1F4, SYD_THEMA  ;
DR   B9K8E5, SYD_THENN  ;  B0K978, SYD_THEP3  ;  B0K0N5, SYD_THEPX  ;
DR   B1LBH9, SYD_THESQ  ;  Q72KH6, SYD_THET2  ;  Q5SKD2, SYD_THET8  ;
DR   P36419, SYD_THETH  ;  Q8RAI7, SYD_THETN  ;  Q979P6, SYD_THEVO  ;
DR   B5YJP5, SYD_THEYD  ;  Q31H87, SYD_THICR  ;  Q3SLL2, SYD_THIDA  ;
DR   B8GUK0, SYD_THISH  ;  C4LBN4, SYD_TOLAT  ;  Q73MC2, SYD_TREDE  ;
DR   O83950, SYD_TREPA  ;  B2S4M2, SYD_TREPS  ;  Q112K0, SYD_TRIEI  ;
DR   B1GZY6, SYD_UNCTG  ;  Q9PQK5, SYD_UREPA  ;  C5CWX8, SYD_VARPS  ;
DR   A1WHI6, SYD_VEREI  ;  A5F263, SYD_VIBC3  ;  Q9KSU0, SYD_VIBCH  ;
DR   C3LLL2, SYD_VIBCM  ;  Q5E6A2, SYD_VIBF1  ;  B5FCP9, SYD_VIBFM  ;
DR   A7N1J1, SYD_VIBHB  ;  Q87QV2, SYD_VIBPA  ;  B7VMI0, SYD_VIBSL  ;
DR   Q8DAN7, SYD_VIBVU  ;  Q7MJ74, SYD_VIBVY  ;  Q73HX6, SYD_WOLPM  ;
DR   B3CPJ5, SYD_WOLPP  ;  Q7M8A6, SYD_WOLSU  ;  Q5GTS0, SYD_WOLTR  ;
DR   C0R2K4, SYD_WOLWR  ;  Q8PHU5, SYD_XANAC  ;  Q3BQE6, SYD_XANC5  ;
DR   Q4UXM5, SYD_XANC8  ;  B0RPX9, SYD_XANCB  ;  Q8P6E0, SYD_XANCP  ;
DR   Q2P582, SYD_XANOM  ;  B2STK7, SYD_XANOP  ;  Q5H2B1, SYD_XANOR  ;
DR   A7IK27, SYD_XANP2  ;  B2I4Y5, SYD_XYLF2  ;  Q9PCC5, SYD_XYLFA  ;
DR   B0U2I5, SYD_XYLFM  ;  Q87CW0, SYD_XYLFT  ;  A1JRL1, SYD_YERE8  ;
DR   A7FID0, SYD_YERP3  ;  Q1C820, SYD_YERPA  ;  B2K319, SYD_YERPB  ;
DR   Q8ZEV0, SYD_YERPE  ;  A9QYX8, SYD_YERPG  ;  Q1CJH0, SYD_YERPN  ;
DR   A4TJK5, SYD_YERPP  ;  Q66AU4, SYD_YERPS  ;  B1JLL5, SYD_YERPY  ;
DR   Q5NPM1, SYD_ZYMMO  ;
//
ID   6.1.1.13
DE   D-alanine--poly(phosphoribitol) ligase.
AN   D-alanine-activating enzyme.
AN   D-alanine-D-alanyl carrier protein ligase.
AN   D-alanine-membrane acceptor ligase.
AN   D-alanine: membrane acceptor ligase.
AN   D-alanyl-poly(phosphoribitol) synthetase.
CA   ATP + D-alanine + poly(ribitol phosphate) = AMP + diphosphate + O-D-
CA   alanyl-poly(ribitol phosphate).
CC   -!- A thioester bond is formed transiently between D-alanine and the
CC       sulfhydryl group of the 4'-phosphopantetheine prosthetic group of
CC       D-alanyl carrier protein during the activation of the alanine.
CC   -!- Involved in the synthesis of teichoic acids.
DR   A7ZA74, DLTA_BACA2 ;  C3P4I7, DLTA_BACAA ;  C3LAH8, DLTA_BACAC ;
DR   A0RBJ0, DLTA_BACAH ;  Q81T97, DLTA_BACAN ;  B7JFV5, DLTA_BACC0 ;
DR   Q73BD2, DLTA_BACC1 ;  B7IN64, DLTA_BACC2 ;  C1EM80, DLTA_BACC3 ;
DR   B7HHC6, DLTA_BACC4 ;  B7HK95, DLTA_BACC7 ;  A7GMR0, DLTA_BACCN ;
DR   B9IUW2, DLTA_BACCQ ;  Q81G39, DLTA_BACCR ;  Q63E02, DLTA_BACCZ ;
DR   Q6HLH7, DLTA_BACHK ;  Q65DH1, DLTA_BACLD ;  P39581, DLTA_BACSU ;
DR   A9VKV6, DLTA_BACWK ;  Q03AZ2, DLTA_LACC3 ;  B3WC77, DLTA_LACCB ;
DR   Q9CG49, DLTA_LACLA ;  Q88VM6, DLTA_LACPL ;  P35854, DLTA_LACRH ;
DR   Q92D47, DLTA_LISIN ;  C1L1P5, DLTA_LISMC ;  Q721J2, DLTA_LISMF ;
DR   B8DEG2, DLTA_LISMH ;  Q8Y8D4, DLTA_LISMO ;  A0AH92, DLTA_LISW6 ;
DR   A7X0D6, DLTA_STAA1 ;  A6U039, DLTA_STAA2 ;  Q2FIE3, DLTA_STAA3 ;
DR   Q2FZW6, DLTA_STAA8 ;  A5IRB0, DLTA_STAA9 ;  Q2YWQ8, DLTA_STAAB ;
DR   Q5HHF2, DLTA_STAAC ;  A6QFE3, DLTA_STAAE ;  P68876, DLTA_STAAM ;
DR   P99107, DLTA_STAAN ;  Q6GIF6, DLTA_STAAR ;  Q6GAZ4, DLTA_STAAS ;
DR   A8Z1J1, DLTA_STAAT ;  P0C397, DLTA_STAAU ;  P68878, DLTA_STAAW ;
DR   Q5HQN0, DLTA_STAEQ ;  Q8CT93, DLTA_STAES ;  Q4L4U5, DLTA_STAHJ ;
DR   Q9X2N4, DLTA_STAXY ;  Q3JZ94, DLTA_STRA1 ;  Q8VM67, DLTA_STRA3 ;
DR   P59591, DLTA_STRA5 ;  C0MBD6, DLTA_STRE4 ;  Q53526, DLTA_STRMU ;
DR   Q99ZA6, DLTA_STRP1 ;  Q04HZ7, DLTA_STRP2 ;  P0DA64, DLTA_STRP3 ;
DR   Q5XBN5, DLTA_STRP6 ;  C1CB20, DLTA_STRP7 ;  Q8P0J9, DLTA_STRP8 ;
DR   Q1JLB7, DLTA_STRPC ;  Q1JGF0, DLTA_STRPD ;  Q1J667, DLTA_STRPF ;
DR   A2RE45, DLTA_STRPG ;  B8ZQ14, DLTA_STRPJ ;  Q48SZ3, DLTA_STRPM ;
DR   P0A398, DLTA_STRPN ;  P0DA65, DLTA_STRPQ ;  B5XLX5, DLTA_STRPZ ;
DR   P0A399, DLTA_STRR6 ;  C1CNE9, DLTA_STRZP ;  C1CU95, DLTA_STRZT ;
DR   Q88VM8, DLTC1_LACPL;  Q88X40, DLTC2_LACPL;  Q8GR69, DLTC_ABIDE ;
DR   A7ZA76, DLTC_BACA2 ;  C3P4I5, DLTC_BACAA ;  C3LAI0, DLTC_BACAC ;
DR   Q81T99, DLTC_BACAN ;  B7JFV3, DLTC_BACC0 ;  P61398, DLTC_BACC1 ;
DR   B7IN62, DLTC_BACC2 ;  C1EM78, DLTC_BACC3 ;  B7HHC4, DLTC_BACC4 ;
DR   B7HK93, DLTC_BACC7 ;  B9IUW0, DLTC_BACCQ ;  Q81G41, DLTC_BACCR ;
DR   Q63E04, DLTC_BACCZ ;  Q6HLH9, DLTC_BACHK ;  Q65DG9, DLTC_BACLD ;
DR   A8FFX3, DLTC_BACP2 ;  P39579, DLTC_BACSU ;  A9VKV4, DLTC_BACWK ;
DR   Q830N2, DLTC_ENTFA ;  Q5FHV3, DLTC_LACAC ;  Q03AZ0, DLTC_LACC3 ;
DR   B3WC79, DLTC_LACCB ;  Q1G852, DLTC_LACDA ;  Q047K9, DLTC_LACDB ;
DR   Q040N1, DLTC_LACGA ;  A8YTM4, DLTC_LACH4 ;  P61399, DLTC_LACJO ;
DR   Q9CG51, DLTC_LACLA ;  A2RKK0, DLTC_LACLM ;  Q02YS9, DLTC_LACLS ;
DR   P55153, DLTC_LACRH ;  Q38YM9, DLTC_LACSS ;  B1MZW0, DLTC_LEUCK ;
DR   Q03V70, DLTC_LEUMM ;  Q92D49, DLTC_LISIN ;  C1L1P3, DLTC_LISMC ;
DR   Q721J4, DLTC_LISMF ;  B8DEG4, DLTC_LISMH ;  Q9S389, DLTC_LISMO ;
DR   A0AH90, DLTC_LISW6 ;  A7X0D9, DLTC_STAA1 ;  A6U041, DLTC_STAA2 ;
DR   Q2FIE1, DLTC_STAA3 ;  Q2FZW4, DLTC_STAA8 ;  A5IRB2, DLTC_STAA9 ;
DR   Q2YWQ6, DLTC_STAAB ;  Q5HHF0, DLTC_STAAC ;  A6QFE5, DLTC_STAAE ;
DR   P0A018, DLTC_STAAM ;  P0A019, DLTC_STAAN ;  Q6GIF4, DLTC_STAAR ;
DR   Q6GAZ2, DLTC_STAAS ;  A8Z1J3, DLTC_STAAT ;  P0C426, DLTC_STAAU ;
DR   P0A020, DLTC_STAAW ;  B9DIY6, DLTC_STACT ;  Q5HQM8, DLTC_STAEQ ;
DR   Q8CPW0, DLTC_STAES ;  Q4L4U7, DLTC_STAHJ ;  Q49W73, DLTC_STAS1 ;
DR   Q9X2N6, DLTC_STAXY ;  Q3JZ96, DLTC_STRA1 ;  P0A3A0, DLTC_STRA3 ;
DR   P0A3A1, DLTC_STRA5 ;  C0MBD4, DLTC_STRE4 ;  B4U3P0, DLTC_STREM ;
DR   A8AUB8, DLTC_STRGC ;  O70055, DLTC_STRMU ;  P63959, DLTC_STRP1 ;
DR   Q04HZ9, DLTC_STRP2 ;  P0DA66, DLTC_STRP3 ;  B5E3R6, DLTC_STRP4 ;
DR   Q5XBN7, DLTC_STRP6 ;  C1CB19, DLTC_STRP7 ;  P63961, DLTC_STRP8 ;
DR   Q1JBD6, DLTC_STRPB ;  Q1JLB9, DLTC_STRPC ;  Q1JGF2, DLTC_STRPD ;
DR   Q1J669, DLTC_STRPF ;  A2RE47, DLTC_STRPG ;  B1I9Y6, DLTC_STRPI ;
DR   B8ZQ12, DLTC_STRPJ ;  Q48SZ5, DLTC_STRPM ;  P63957, DLTC_STRPN ;
DR   P0DA67, DLTC_STRPQ ;  B2INJ3, DLTC_STRPS ;  B5XLX3, DLTC_STRPZ ;
DR   P63958, DLTC_STRR6 ;  A4W0A9, DLTC_STRS2 ;  C0MDC9, DLTC_STRS7 ;
DR   A3CR85, DLTC_STRSV ;  A4VU17, DLTC_STRSY ;  Q5M0A6, DLTC_STRT1 ;
DR   Q5M4V3, DLTC_STRT2 ;  Q03L69, DLTC_STRTD ;  B9DSG7, DLTC_STRU0 ;
DR   C1CHH5, DLTC_STRZJ ;  C1CNE7, DLTC_STRZP ;  C1CU93, DLTC_STRZT ;
//
ID   6.1.1.14
DE   Glycine--tRNA ligase.
AN   Glycyl translase.
AN   Glycyl-tRNA synthetase.
CA   ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).
PR   PROSITE; PDOC00363;
DR   Q06817, SYG2_YEAST ;  B0CEQ4, SYGA_ACAM1 ;  A1TUT1, SYGA_ACIAC ;
DR   B9MCM3, SYGA_ACIET ;  A1W3F2, SYGA_ACISJ ;  A3N398, SYGA_ACTP2 ;
DR   B3GZ52, SYGA_ACTP7 ;  B0BSX2, SYGA_ACTPJ ;  A6VLE0, SYGA_ACTSZ ;
DR   A0KEK0, SYGA_AERHH ;  A4STG2, SYGA_AERS4 ;  Q8UHP1, SYGA_AGRT5 ;
DR   B6EGT2, SYGA_ALISL ;  B4S278, SYGA_ALTMD ;  B8JDD9, SYGA_ANAD2 ;
DR   Q2IQJ6, SYGA_ANADE ;  B4UG88, SYGA_ANASK ;  Q3M502, SYGA_ANAVT ;
DR   O67081, SYGA_AQUAE ;  A8EW78, SYGA_ARCB4 ;  A7Z6U1, SYGA_BACA2 ;
DR   Q9KD49, SYGA_BACHD ;  Q65H75, SYGA_BACLD ;  A8FFB1, SYGA_BACP2 ;
DR   Q5WHD6, SYGA_BACSK ;  P54380, SYGA_BACSU ;  Q1LTU1, SYGA_BAUCH ;
DR   Q2KX74, SYGA_BORA1 ;  Q7W0Q6, SYGA_BORPE ;  C0R0J6, SYGA_BRAHW ;
DR   Q89S70, SYGA_BRAJA ;  C0ZB87, SYGA_BREBN ;  Q2YME4, SYGA_BRUA2 ;
DR   Q57EW2, SYGA_BRUAB ;  A9M8H7, SYGA_BRUC2 ;  C0RHB0, SYGA_BRUMB ;
DR   Q8YFJ0, SYGA_BRUME ;  B0CK89, SYGA_BRUSI ;  Q8G2C1, SYGA_BRUSU ;
DR   B8D8T7, SYGA_BUCA5 ;  P57236, SYGA_BUCAI ;  Q8KA06, SYGA_BUCAP ;
DR   B8D741, SYGA_BUCAT ;  Q89AV6, SYGA_BUCBP ;  A7ZDY6, SYGA_CAMC1 ;
DR   A7GZB9, SYGA_CAMC5 ;  A0RPS8, SYGA_CAMFF ;  A7I198, SYGA_CAMHC ;
DR   A8FLD3, SYGA_CAMJ8 ;  A7H4C1, SYGA_CAMJD ;  Q9PPK3, SYGA_CAMJE ;
DR   A1VZ59, SYGA_CAMJJ ;  Q5HV77, SYGA_CAMJR ;  B9KCN6, SYGA_CAMLR ;
DR   B8H516, SYGA_CAUCN ;  Q9A8L2, SYGA_CAUCR ;  A8ARE6, SYGA_CITK8 ;
DR   Q182B9, SYGA_CLOD6 ;  B5Y7V5, SYGA_COPPD ;  B6J8U0, SYGA_COXB1 ;
DR   B6J2A7, SYGA_COXB2 ;  A9KBT8, SYGA_COXBN ;  A9NB98, SYGA_COXBR ;
DR   P94616, SYGA_COXBU ;  B2AH98, SYGA_CUPTR ;  B1WQ23, SYGA_CYAA5 ;
DR   B8HU74, SYGA_CYAP4 ;  B7KHU5, SYGA_CYAP7 ;  B7K0B0, SYGA_CYAP8 ;
DR   A9BXZ7, SYGA_DELAS ;  B8FKD9, SYGA_DESAA ;  C6BV68, SYGA_DESAD ;
DR   C0QJ90, SYGA_DESAH ;  B1I1S8, SYGA_DESAP ;  B8IZ95, SYGA_DESDA ;
DR   Q30ZR5, SYGA_DESDG ;  B8FUJ1, SYGA_DESHD ;  Q24SW9, SYGA_DESHY ;
DR   C4XS53, SYGA_DESMR ;  A9A0L5, SYGA_DESOH ;  Q6AS28, SYGA_DESPS ;
DR   A4J7D0, SYGA_DESRM ;  Q72AU2, SYGA_DESVH ;  B8DPG0, SYGA_DESVM ;
DR   A1VCW8, SYGA_DESVV ;  A5EV42, SYGA_DICNV ;  B5YES5, SYGA_DICT6 ;
DR   B8E0E9, SYGA_DICTD ;  A7ZTA6, SYGA_ECO24 ;  B7ULC0, SYGA_ECO27 ;
DR   B7MER5, SYGA_ECO45 ;  B7L6X1, SYGA_ECO55 ;  P67026, SYGA_ECO57 ;
DR   B5YVL2, SYGA_ECO5E ;  B7NP56, SYGA_ECO7I ;  B7N203, SYGA_ECO81 ;
DR   B7M3I2, SYGA_ECO8A ;  C4ZXF0, SYGA_ECOBW ;  A8A617, SYGA_ECOHS ;
DR   A1AHA1, SYGA_ECOK1 ;  Q0TBP3, SYGA_ECOL5 ;  P67025, SYGA_ECOL6 ;
DR   B1IZN3, SYGA_ECOLC ;  P00960, SYGA_ECOLI ;  B7NEL1, SYGA_ECOLU ;
DR   B6I3D0, SYGA_ECOSE ;  B1LJC1, SYGA_ECOSM ;  Q1R536, SYGA_ECOUT ;
DR   C5B996, SYGA_EDWI9 ;  A4W572, SYGA_ENT38 ;  Q831U2, SYGA_ENTFA ;
DR   A7MKR9, SYGA_ENTS8 ;  Q6DB18, SYGA_ERWCT ;  B2VCH0, SYGA_ERWT9 ;
DR   B7LTH4, SYGA_ESCF3 ;  B1YL75, SYGA_EXIS2 ;  A7HLW9, SYGA_FERNB ;
DR   B0TZH7, SYGA_FRAP2 ;  A7NAI8, SYGA_FRATF ;  Q2A4U1, SYGA_FRATH ;
DR   B2SFN3, SYGA_FRATM ;  A0Q599, SYGA_FRATN ;  A4IZJ6, SYGA_FRATW ;
DR   Q8RH45, SYGA_FUSNN ;  B5ED83, SYGA_GEOBB ;  B3E622, SYGA_GEOLS ;
DR   Q39RG4, SYGA_GEOMG ;  Q74FM8, SYGA_GEOSL ;  A5G7Q8, SYGA_GEOUR ;
DR   Q7NKN1, SYGA_GLOVI ;  Q0BQA2, SYGA_GRABC ;  Q7VKG5, SYGA_HAEDU ;
DR   Q4QLY1, SYGA_HAEI8 ;  A5UDE0, SYGA_HAEIE ;  A5UI68, SYGA_HAEIG ;
DR   P43821, SYGA_HAEIN ;  B8F706, SYGA_HAEPS ;  C4K459, SYGA_HAMD5 ;
DR   Q17X26, SYGA_HELAH ;  Q7VIS3, SYGA_HELHP ;  B0TAF7, SYGA_HELMI ;
DR   B6JMI0, SYGA_HELP2 ;  B5Z7W3, SYGA_HELPG ;  Q1CSR1, SYGA_HELPH ;
DR   Q9ZKP1, SYGA_HELPJ ;  B2UUA6, SYGA_HELPS ;  P56453, SYGA_HELPY ;
DR   A4G262, SYGA_HERAR ;  A6SV19, SYGA_JANMA ;  B5XMY6, SYGA_KLEP3 ;
DR   A6TFH5, SYGA_KLEP7 ;  Q03SC6, SYGA_LACBA ;  Q038U2, SYGA_LACC3 ;
DR   Q9CGK1, SYGA_LACLA ;  Q02Z94, SYGA_LACLS ;  Q88VS2, SYGA_LACPL ;
DR   Q1WTP0, SYGA_LACS1 ;  Q38XA0, SYGA_LACSS ;  C1D4E5, SYGA_LARHH ;
DR   Q1MRM0, SYGA_LAWIP ;  B1Y7P3, SYGA_LEPCP ;  B1MZ61, SYGA_LEUCK ;
DR   Q03WY0, SYGA_LEUMM ;  Q92BQ1, SYGA_LISIN ;  C1KVA6, SYGA_LISMC ;
DR   Q71ZL1, SYGA_LISMF ;  B8DE52, SYGA_LISMH ;  Q8Y753, SYGA_LISMO ;
DR   A0AIR0, SYGA_LISW6 ;  Q65R50, SYGA_MANSM ;  Q0AML4, SYGA_MARMM ;
DR   Q11KG2, SYGA_MESSB ;  Q1H3M2, SYGA_METFK ;  A2SL95, SYGA_METPP ;
DR   B1M1W4, SYGA_METRJ ;  B0JSD7, SYGA_MICAN ;  Q2RKV6, SYGA_MOOTA ;
DR   P77892, SYGA_MORCA ;  B2A1Y5, SYGA_NATTJ ;  Q5F4Y8, SYGA_NEIG1 ;
DR   B4RJG2, SYGA_NEIG2 ;  A9M125, SYGA_NEIM0 ;  P67028, SYGA_NEIMA ;
DR   P67029, SYGA_NEIMB ;  A1KW09, SYGA_NEIMF ;  Q2YBL2, SYGA_NITMU ;
DR   A6Q559, SYGA_NITSB ;  B2J0V5, SYGA_NOSP7 ;  Q8YVJ2, SYGA_NOSS1 ;
DR   Q8EPY1, SYGA_OCEIH ;  A6WW98, SYGA_OCHA4 ;  Q04F71, SYGA_OENOB ;
DR   B6JEV8, SYGA_OLICO ;  A1AZF6, SYGA_PARDP ;  P57904, SYGA_PASMU ;
DR   C6DII8, SYGA_PECCP ;  Q03F65, SYGA_PEDPA ;  Q3A8N6, SYGA_PELCD ;
DR   A1ATI5, SYGA_PELPD ;  A5D3W9, SYGA_PELTS ;  A9BG54, SYGA_PETMO ;
DR   Q7N9M7, SYGA_PHOLL ;  A1VJD7, SYGA_POLNA ;  B1XS10, SYGA_POLNS ;
DR   Q124E7, SYGA_POLSJ ;  A4T011, SYGA_POLSQ ;  A2C3W9, SYGA_PROM1 ;
DR   A8G5W1, SYGA_PROM2 ;  A9BBH9, SYGA_PROM4 ;  A2BXN1, SYGA_PROM5 ;
DR   Q7VB32, SYGA_PROMA ;  B4EZ94, SYGA_PROMH ;  Q7V8Q1, SYGA_PROMM ;
DR   Q7V0T8, SYGA_PROMP ;  Q46JQ9, SYGA_PROMT ;  Q15ZY9, SYGA_PSEA6 ;
DR   A6UX70, SYGA_PSEA7 ;  B7V0P4, SYGA_PSEA8 ;  Q02V72, SYGA_PSEAB ;
DR   Q9I7B7, SYGA_PSEAE ;  Q1IH41, SYGA_PSEE4 ;  Q4KKR7, SYGA_PSEF5 ;
DR   C3KE41, SYGA_PSEFS ;  Q3IDE6, SYGA_PSEHT ;  A4XN73, SYGA_PSEMY ;
DR   A5VWJ2, SYGA_PSEP1 ;  Q3KKF2, SYGA_PSEPF ;  B0KF23, SYGA_PSEPG ;
DR   Q88RR8, SYGA_PSEPK ;  B1J426, SYGA_PSEPW ;  Q88B36, SYGA_PSESM ;
DR   A1T0Y6, SYGA_PSYIN ;  Q1LR92, SYGA_RALME ;  Q8Y211, SYGA_RALSO ;
DR   Q986B6, SYGA_RHILO ;  B5ZS33, SYGA_RHILW ;  Q92RL5, SYGA_RHIME ;
DR   Q20YB4, SYGA_RHOPB ;  Q2RQ44, SYGA_RHORT ;  C3PLY5, SYGA_RICAE ;
DR   A8GQ65, SYGA_RICAH ;  A8GUQ3, SYGA_RICB8 ;  Q1RGS3, SYGA_RICBR ;
DR   A8F072, SYGA_RICCK ;  Q92G10, SYGA_RICCN ;  Q4UJU1, SYGA_RICFE ;
DR   A8F2Z1, SYGA_RICM5 ;  Q9ZCB0, SYGA_RICPR ;  C4K2V4, SYGA_RICPU ;
DR   B0BVK1, SYGA_RICRO ;  A8GU09, SYGA_RICRS ;  Q68VR3, SYGA_RICTY ;
DR   Q21PU3, SYGA_SACD2 ;  B5EX66, SYGA_SALA4 ;  A9MLF6, SYGA_SALAR ;
DR   Q57IG5, SYGA_SALCH ;  B5FLD0, SYGA_SALDC ;  B5R4P3, SYGA_SALEP ;
DR   B5RGM1, SYGA_SALG2 ;  B4T946, SYGA_SALHS ;  B4SWK2, SYGA_SALNS ;
DR   Q5PLN1, SYGA_SALPA ;  C0Q1B7, SYGA_SALPC ;  B5BHU2, SYGA_SALPK ;
DR   B4TZ50, SYGA_SALSV ;  Q8Z2B4, SYGA_SALTI ;  Q8ZL95, SYGA_SALTY ;
DR   A8G7T9, SYGA_SERP5 ;  A1S1I2, SYGA_SHEAM ;  B8E3Q6, SYGA_SHEB2 ;
DR   A3CYI7, SYGA_SHEB5 ;  A6WH93, SYGA_SHEB8 ;  A9KU84, SYGA_SHEB9 ;
DR   Q12TC0, SYGA_SHEDO ;  Q08A45, SYGA_SHEFN ;  B0TLB0, SYGA_SHEHH ;
DR   A3Q8T5, SYGA_SHELP ;  Q8EKS5, SYGA_SHEON ;  A4Y1B0, SYGA_SHEPC ;
DR   B8CH77, SYGA_SHEPW ;  A0KR43, SYGA_SHESA ;  Q0HPC6, SYGA_SHESM ;
DR   Q0I0U0, SYGA_SHESR ;  A1RDW5, SYGA_SHESW ;  B2U565, SYGA_SHIB3 ;
DR   Q31V61, SYGA_SHIBS ;  Q328M0, SYGA_SHIDS ;  Q0SY79, SYGA_SHIF8 ;
DR   P67027, SYGA_SHIFL ;  Q3YVU1, SYGA_SHISS ;  Q2NX39, SYGA_SODGM ;
DR   A9GUD0, SYGA_SORC5 ;  A5VFX8, SYGA_SPHWW ;  Q3K3B1, SYGA_STRA1 ;
DR   Q8CX31, SYGA_STRA3 ;  Q8E1T5, SYGA_STRA5 ;  C0M953, SYGA_STRE4 ;
DR   B4U1J1, SYGA_STREM ;  A8AVS4, SYGA_STRGC ;  B4SNR2, SYGA_STRM5 ;
DR   B2FP48, SYGA_STRMK ;  Q8CWY6, SYGA_STRMU ;  Q99YI3, SYGA_STRP1 ;
DR   Q04JM7, SYGA_STRP2 ;  P0DG36, SYGA_STRP3 ;  B5E643, SYGA_STRP4 ;
DR   Q5XAJ5, SYGA_STRP6 ;  C1C871, SYGA_STRP7 ;  Q8NZW6, SYGA_STRP8 ;
DR   Q1JAE8, SYGA_STRPB ;  Q1JKJ9, SYGA_STRPC ;  Q1JFJ0, SYGA_STRPD ;
DR   Q1J5E0, SYGA_STRPF ;  A2RD23, SYGA_STRPG ;  B1ICQ6, SYGA_STRPI ;
DR   B8ZL21, SYGA_STRPJ ;  Q48RX2, SYGA_STRPM ;  Q97PW5, SYGA_STRPN ;
DR   P0DG37, SYGA_STRPQ ;  B2IQU2, SYGA_STRPS ;  B5XMN0, SYGA_STRPZ ;
DR   Q8DP65, SYGA_STRR6 ;  A4W3J5, SYGA_STRS2 ;  C0MDQ4, SYGA_STRS7 ;
DR   A3CQ06, SYGA_STRSV ;  A4VX92, SYGA_STRSY ;  Q5M0Y6, SYGA_STRT1 ;
DR   Q5M5H3, SYGA_STRT2 ;  Q03LV7, SYGA_STRTD ;  B9DV93, SYGA_STRU0 ;
DR   C1CF58, SYGA_STRZJ ;  C1CLH5, SYGA_STRZP ;  C1CQP3, SYGA_STRZT ;
DR   Q30PF0, SYGA_SULDN ;  A6Q760, SYGA_SULNB ;  B2V9P8, SYGA_SULSY ;
DR   Q2LVI0, SYGA_SYNAS ;  Q31KD2, SYGA_SYNE7 ;  A0LL24, SYGA_SYNFM ;
DR   B1XNV4, SYGA_SYNP2 ;  Q5N1I3, SYGA_SYNP6 ;  A5GMN1, SYGA_SYNPW ;
DR   Q7U5N2, SYGA_SYNPX ;  Q3AWZ4, SYGA_SYNS9 ;  Q3ALF2, SYGA_SYNSC ;
DR   Q0AWT5, SYGA_SYNWW ;  Q55716, SYGA_SYNY3 ;  C5BKP0, SYGA_TERTT ;
DR   Q8DK36, SYGA_THEEB ;  Q9WY59, SYGA_THEMA ;  B9K6R2, SYGA_THENN ;
DR   A5IKK5, SYGA_THEP1 ;  B1L9T6, SYGA_THESQ ;  B5YJ13, SYGA_THEYD ;
DR   Q3SGE9, SYGA_THIDA ;  C4L763, SYGA_TOLAT ;  Q10XW9, SYGA_TRIEI ;
DR   C5CM90, SYGA_VARPS ;  Q9KVW7, SYGA_VIBCH ;  Q5E8Y6, SYGA_VIBF1 ;
DR   B5FEV9, SYGA_VIBFM ;  A7N1D9, SYGA_VIBHB ;  Q87TP7, SYGA_VIBPA ;
DR   B7VGK7, SYGA_VIBSL ;  Q8DDJ8, SYGA_VIBVU ;  Q7MQI7, SYGA_VIBVY ;
DR   Q8D1W3, SYGA_WIGBR ;  Q7M7S2, SYGA_WOLSU ;  Q8PEX9, SYGA_XANAC ;
DR   Q3BMH1, SYGA_XANC5 ;  Q4UP07, SYGA_XANC8 ;  B0RYX4, SYGA_XANCB ;
DR   Q8P3I4, SYGA_XANCP ;  Q2NXS9, SYGA_XANOM ;  B2SII2, SYGA_XANOP ;
DR   B2I4M8, SYGA_XYLF2 ;  Q9PC25, SYGA_XYLFA ;  B0U7B1, SYGA_XYLFM ;
DR   Q87D46, SYGA_XYLFT ;  A1JT51, SYGA_YERE8 ;  A7FP96, SYGA_YERP3 ;
DR   Q1C3J9, SYGA_YERPA ;  B2K7F7, SYGA_YERPB ;  Q8Z9W6, SYGA_YERPE ;
DR   A9R4G0, SYGA_YERPG ;  Q1CD85, SYGA_YERPN ;  A4TGN6, SYGA_YERPP ;
DR   Q663V9, SYGA_YERPS ;  B1JH06, SYGA_YERPY ;  Q5NMJ1, SYGA_ZYMMO ;
DR   B0CD57, SYGB_ACAM1 ;  A1TUT0, SYGB_ACIAC ;  Q6F7L8, SYGB_ACIAD ;
DR   B7GVW2, SYGB_ACIB3 ;  B7IA77, SYGB_ACIB5 ;  B2HZR3, SYGB_ACIBC ;
DR   B0VQA1, SYGB_ACIBS ;  A3M9C2, SYGB_ACIBT ;  B0V7W2, SYGB_ACIBY ;
DR   C1F1J0, SYGB_ACIC5 ;  B9MCM4, SYGB_ACIET ;  B7J7P8, SYGB_ACIF2 ;
DR   B5EMS4, SYGB_ACIF5 ;  A1W3F3, SYGB_ACISJ ;  A3N3A1, SYGB_ACTP2 ;
DR   B3GZ55, SYGB_ACTP7 ;  B0BSX5, SYGB_ACTPJ ;  A6VLE1, SYGB_ACTSZ ;
DR   A0KEJ9, SYGB_AERHH ;  A4STG3, SYGB_AERS4 ;  A9CK39, SYGB_AGRT5 ;
DR   B6EGT3, SYGB_ALISL ;  B4S277, SYGB_ALTMD ;  B8JDD8, SYGB_ANAD2 ;
DR   Q2IQJ5, SYGB_ANADE ;  B4UG87, SYGB_ANASK ;  O67898, SYGB_AQUAE ;
DR   Q5P766, SYGB_AROAE ;  A1K3J8, SYGB_AZOSB ;  C1DFV1, SYGB_AZOVD ;
DR   Q9KD48, SYGB_BACHD ;  Q5WHD5, SYGB_BACSK ;  P54381, SYGB_BACSU ;
DR   Q1LTU2, SYGB_BAUCH ;  Q89S69, SYGB_BRAJA ;  A5EED4, SYGB_BRASB ;
DR   B8D8T6, SYGB_BUCA5 ;  P57235, SYGB_BUCAI ;  Q8KA07, SYGB_BUCAP ;
DR   B8D740, SYGB_BUCAT ;  P59573, SYGB_BUCBP ;  Q1R1N7, SYGB_CHRSD ;
DR   A8ARE4, SYGB_CITK8 ;  Q182B8, SYGB_CLOD6 ;  Q48AS2, SYGB_COLP3 ;
DR   A9KBT7, SYGB_COXBN ;  A9NB99, SYGB_COXBR ;  P45651, SYGB_COXBU ;
DR   B7KD52, SYGB_CYAP7 ;  Q47A67, SYGB_DECAR ;  A9BXZ8, SYGB_DELAS ;
DR   B8FKD8, SYGB_DESAA ;  C0QJ89, SYGB_DESAH ;  B1I1T4, SYGB_DESAP ;
DR   Q30ZR6, SYGB_DESDG ;  B8FUJ0, SYGB_DESHD ;  Q24SX0, SYGB_DESHY ;
DR   C4XS54, SYGB_DESMR ;  A4J7C9, SYGB_DESRM ;  Q72AU3, SYGB_DESVH ;
DR   B8DPG1, SYGB_DESVM ;  A1VCW9, SYGB_DESVV ;  A5EV43, SYGB_DICNV ;
DR   B5YES4, SYGB_DICT6 ;  B8E0E8, SYGB_DICTD ;  A8LS45, SYGB_DINSH ;
DR   A7ZTA5, SYGB_ECO24 ;  B7ULB9, SYGB_ECO27 ;  B7MER4, SYGB_ECO45 ;
DR   B7L6X3, SYGB_ECO55 ;  P67031, SYGB_ECO57 ;  B5YVL1, SYGB_ECO5E ;
DR   B7NP55, SYGB_ECO7I ;  B7N1L1, SYGB_ECO81 ;  B7M3I1, SYGB_ECO8A ;
DR   C4ZXE9, SYGB_ECOBW ;  B1X8H5, SYGB_ECODH ;  A8A616, SYGB_ECOHS ;
DR   A1AHA0, SYGB_ECOK1 ;  Q0TBP4, SYGB_ECOL5 ;  P67030, SYGB_ECOL6 ;
DR   B1IZN4, SYGB_ECOLC ;  P00961, SYGB_ECOLI ;  B7NEL0, SYGB_ECOLU ;
DR   B6I3C9, SYGB_ECOSE ;  B1LJC0, SYGB_ECOSM ;  Q1R537, SYGB_ECOUT ;
DR   C5B995, SYGB_EDWI9 ;  A4W573, SYGB_ENT38 ;  Q831U3, SYGB_ENTFA ;
DR   A7MKS3, SYGB_ENTS8 ;  Q6DB17, SYGB_ERWCT ;  B2VCH1, SYGB_ERWT9 ;
DR   B7LTH3, SYGB_ESCF3 ;  Q8RH44, SYGB_FUSNN ;  B5ED84, SYGB_GEOBB ;
DR   B3E621, SYGB_GEOLS ;  Q39RG5, SYGB_GEOMG ;  B9M5V4, SYGB_GEOSF ;
DR   Q74FM7, SYGB_GEOSL ;  C6E0B4, SYGB_GEOSM ;  A5G7Q7, SYGB_GEOUR ;
DR   O30836, SYGB_HAEAE ;  Q7VKG6, SYGB_HAEDU ;  Q4QLY5, SYGB_HAEI8 ;
DR   A5UDE3, SYGB_HAEIE ;  A5UI65, SYGB_HAEIG ;  P43822, SYGB_HAEIN ;
DR   B8F711, SYGB_HAEPS ;  Q0I273, SYGB_HAES1 ;  B0UWA9, SYGB_HAES2 ;
DR   Q2SQY0, SYGB_HAHCH ;  B8CXH5, SYGB_HALOH ;  C4K460, SYGB_HAMD5 ;
DR   B6JMJ2, SYGB_HELP2 ;  B5Z7X4, SYGB_HELPG ;  Q1CSQ2, SYGB_HELPH ;
DR   Q9ZKM9, SYGB_HELPJ ;  B2UUB6, SYGB_HELPS ;  P56454, SYGB_HELPY ;
DR   Q0C4C9, SYGB_HYPNA ;  Q5QY35, SYGB_IDILO ;  A6SV18, SYGB_JANMA ;
DR   B5XMY7, SYGB_KLEP3 ;  A6TFH4, SYGB_KLEP7 ;  Q5FJU0, SYGB_LACAC ;
DR   Q03SC5, SYGB_LACBA ;  Q038U3, SYGB_LACC3 ;  B3WEK6, SYGB_LACCB ;
DR   Q04A23, SYGB_LACDB ;  B2GBZ7, SYGB_LACF3 ;  Q042Y5, SYGB_LACGA ;
DR   A8YVM4, SYGB_LACH4 ;  Q74IZ2, SYGB_LACJO ;  Q9CGK0, SYGB_LACLA ;
DR   A2RL88, SYGB_LACLM ;  Q02Z93, SYGB_LACLS ;  Q88VS3, SYGB_LACPL ;
DR   A5VJI1, SYGB_LACRD ;  B2G6Z6, SYGB_LACRJ ;  Q1WTP1, SYGB_LACS1 ;
DR   Q38X99, SYGB_LACSS ;  Q1MRM1, SYGB_LAWIP ;  B1Y7P2, SYGB_LEPCP ;
DR   B1MZ60, SYGB_LEUCK ;  Q03WY1, SYGB_LEUMM ;  Q92BQ2, SYGB_LISIN ;
DR   C1KVA5, SYGB_LISMC ;  Q71ZL2, SYGB_LISMF ;  B8DE53, SYGB_LISMH ;
DR   Q8Y754, SYGB_LISMO ;  A0AIQ9, SYGB_LISW6 ;  Q2W3X1, SYGB_MAGSA ;
DR   A0L7K9, SYGB_MAGSM ;  Q65R47, SYGB_MANSM ;  A1TWM6, SYGB_MARAV ;
DR   B7KUK7, SYGB_METC4 ;  Q1H3M3, SYGB_METFK ;  B8IBI6, SYGB_METNO ;
DR   B1M1W2, SYGB_METRJ ;  B0UNU2, SYGB_METS4 ;  Q2RKV5, SYGB_MOOTA ;
DR   P77891, SYGB_MORCA ;  Q1D7R9, SYGB_MYXXD ;  B2A1Y6, SYGB_NATTJ ;
DR   Q5F4Y7, SYGB_NEIG1 ;  B4RJG3, SYGB_NEIG2 ;  Q50945, SYGB_NEIGO ;
DR   A9M127, SYGB_NEIM0 ;  Q9JW67, SYGB_NEIMA ;  Q9JXQ5, SYGB_NEIMB ;
DR   A1KW08, SYGB_NEIMF ;  Q0AEY2, SYGB_NITEC ;  Q82VB0, SYGB_NITEU ;
DR   Q8YPT0, SYGB_NOSS1 ;  Q8EPY2, SYGB_OCEIH ;  Q04F69, SYGB_OENOB ;
DR   A1AZF8, SYGB_PARDP ;  P57905, SYGB_PASMU ;  C6DII7, SYGB_PECCP ;
DR   Q03F66, SYGB_PEDPA ;  Q3A8N5, SYGB_PELCD ;  C0QUJ3, SYGB_PERMH ;
DR   B4R9A9, SYGB_PHEZH ;  Q7MB99, SYGB_PHOLL ;  Q6LW15, SYGB_PHOPR ;
DR   A1VJD8, SYGB_POLNA ;  B4EZ95, SYGB_PROMH ;  Q48QJ1, SYGB_PSE14 ;
DR   Q15ZZ0, SYGB_PSEA6 ;  B7V0P3, SYGB_PSEA8 ;  Q02V73, SYGB_PSEAB ;
DR   Q9I7B8, SYGB_PSEAE ;  Q1IH28, SYGB_PSEE4 ;  Q4KKR8, SYGB_PSEF5 ;
DR   C3KE40, SYGB_PSEFS ;  Q3IJ28, SYGB_PSEHT ;  A4XN72, SYGB_PSEMY ;
DR   A5VWJ1, SYGB_PSEP1 ;  Q3KKF3, SYGB_PSEPF ;  B0KF22, SYGB_PSEPG ;
DR   Q88RR9, SYGB_PSEPK ;  B1J425, SYGB_PSEPW ;  Q88B35, SYGB_PSESM ;
DR   Q500T7, SYGB_PSEU2 ;  A4VFG6, SYGB_PSEU5 ;  A1T0Y5, SYGB_PSYIN ;
DR   B2UFN5, SYGB_RALPJ ;  Q8Y213, SYGB_RALSO ;  B3PRI2, SYGB_RHIE6 ;
DR   Q2KBT5, SYGB_RHIEC ;  Q1MKQ6, SYGB_RHIL3 ;  Q986B5, SYGB_RHILO ;
DR   Q92RL2, SYGB_RHIME ;  C3MHD5, SYGB_RHISN ;  B6INH0, SYGB_RHOCS ;
DR   Q2RQ43, SYGB_RHORT ;  A3PH07, SYGB_RHOS1 ;  Q3J5C7, SYGB_RHOS4 ;
DR   C3PLY4, SYGB_RICAE ;  A8GQ64, SYGB_RICAH ;  A8GUQ4, SYGB_RICB8 ;
DR   Q1RGS4, SYGB_RICBR ;  A8F071, SYGB_RICCK ;  Q92G11, SYGB_RICCN ;
DR   Q4UJU2, SYGB_RICFE ;  Q9ZCB1, SYGB_RICPR ;  C4K2V3, SYGB_RICPU ;
DR   Q68VR4, SYGB_RICTY ;  A1AWZ5, SYGB_RUTMC ;  B5EX65, SYGB_SALA4 ;
DR   A9MLF8, SYGB_SALAR ;  Q57IG6, SYGB_SALCH ;  B5FLC9, SYGB_SALDC ;
DR   B5R4P2, SYGB_SALEP ;  B5RGM2, SYGB_SALG2 ;  B4T945, SYGB_SALHS ;
DR   B4SWK1, SYGB_SALNS ;  Q5PLN2, SYGB_SALPA ;  A9MUU1, SYGB_SALPB ;
DR   C0Q1B6, SYGB_SALPC ;  B5BHU1, SYGB_SALPK ;  B4TZ49, SYGB_SALSV ;
DR   Q8Z2B3, SYGB_SALTI ;  Q8ZL96, SYGB_SALTY ;  A8G7U0, SYGB_SERP5 ;
DR   A1S1I1, SYGB_SHEAM ;  B8E3Q5, SYGB_SHEB2 ;  A3CYI6, SYGB_SHEB5 ;
DR   A6WH92, SYGB_SHEB8 ;  A9KU83, SYGB_SHEB9 ;  Q12TC1, SYGB_SHEDO ;
DR   Q08A46, SYGB_SHEFN ;  B0TLA9, SYGB_SHEHH ;  A3Q8T4, SYGB_SHELP ;
DR   Q8EKS6, SYGB_SHEON ;  A8GYE8, SYGB_SHEPA ;  A4Y1A9, SYGB_SHEPC ;
DR   B8CH76, SYGB_SHEPW ;  A0KR42, SYGB_SHESA ;  A8FP54, SYGB_SHESH ;
DR   Q0HPC7, SYGB_SHESM ;  Q0I0U1, SYGB_SHESR ;  A1RDW4, SYGB_SHESW ;
DR   B1KCY4, SYGB_SHEWM ;  B2U566, SYGB_SHIB3 ;  Q31V62, SYGB_SHIBS ;
DR   Q328L9, SYGB_SHIDS ;  Q0SY78, SYGB_SHIF8 ;  Q83J38, SYGB_SHIFL ;
DR   Q3YVU0, SYGB_SHISS ;  Q1GE74, SYGB_SILST ;  A6U6P3, SYGB_SINMW ;
DR   Q2NX38, SYGB_SODGM ;  Q3K3A9, SYGB_STRA1 ;  Q8CX30, SYGB_STRA3 ;
DR   Q8E1T3, SYGB_STRA5 ;  C0M9J7, SYGB_STRE4 ;  A8AVS5, SYGB_STRGC ;
DR   Q8CWY5, SYGB_STRMU ;  Q99YI4, SYGB_STRP1 ;  Q04JM8, SYGB_STRP2 ;
DR   P0DG38, SYGB_STRP3 ;  B5E642, SYGB_STRP4 ;  Q5XAJ6, SYGB_STRP6 ;
DR   C1C870, SYGB_STRP7 ;  Q8NZW7, SYGB_STRP8 ;  Q1JKK0, SYGB_STRPC ;
DR   Q1JFJ1, SYGB_STRPD ;  Q1J5E1, SYGB_STRPF ;  A2RD24, SYGB_STRPG ;
DR   B1ICQ5, SYGB_STRPI ;  B8ZL20, SYGB_STRPJ ;  Q48RX3, SYGB_STRPM ;
DR   Q97PW6, SYGB_STRPN ;  P0DG39, SYGB_STRPQ ;  B2IQU1, SYGB_STRPS ;
DR   B5XMM9, SYGB_STRPZ ;  Q8DP66, SYGB_STRR6 ;  A4W3J4, SYGB_STRS2 ;
DR   C0MDQ3, SYGB_STRS7 ;  A3CQ05, SYGB_STRSV ;  A4VX91, SYGB_STRSY ;
DR   Q03LV6, SYGB_STRTD ;  B9DV92, SYGB_STRU0 ;  C1CF57, SYGB_STRZJ ;
DR   C1CLH4, SYGB_STRZP ;  C1CQP4, SYGB_STRZT ;  B2V9P9, SYGB_SULSY ;
DR   Q2LVI9, SYGB_SYNAS ;  B1XK79, SYGB_SYNP2 ;  Q0AWT6, SYGB_SYNWW ;
DR   Q55690, SYGB_SYNY3 ;  Q9WY60, SYGB_THEMA ;  B9K6R1, SYGB_THENN ;
DR   A5IKK4, SYGB_THEP1 ;  B1L9T5, SYGB_THESQ ;  B5YJ12, SYGB_THEYD ;
DR   Q3SGF0, SYGB_THIDA ;  C4L762, SYGB_TOLAT ;  Q10WA6, SYGB_TRIEI ;
DR   A5CW91, SYGB_VESOH ;  A5F487, SYGB_VIBC3 ;  Q9KVW8, SYGB_VIBCH ;
DR   C3LP93, SYGB_VIBCM ;  Q5E8Y5, SYGB_VIBF1 ;  B5FEW0, SYGB_VIBFM ;
DR   A7N1D8, SYGB_VIBHB ;  Q87TP8, SYGB_VIBPA ;  B7VGK6, SYGB_VIBSL ;
DR   Q8DDJ7, SYGB_VIBVU ;  Q7MQI8, SYGB_VIBVY ;  Q4UP08, SYGB_XANC8 ;
DR   B0RYX3, SYGB_XANCB ;  Q8P3I5, SYGB_XANCP ;  B2I4M9, SYGB_XYLF2 ;
DR   Q9PC26, SYGB_XYLFA ;  B0U7B2, SYGB_XYLFM ;  Q87D45, SYGB_XYLFT ;
DR   A1JT50, SYGB_YERE8 ;  A7FP95, SYGB_YERP3 ;  Q1C3J8, SYGB_YERPA ;
DR   B2K7F8, SYGB_YERPB ;  Q8Z9W7, SYGB_YERPE ;  A9R4F9, SYGB_YERPG ;
DR   Q1CD86, SYGB_YERPN ;  A4TGN7, SYGB_YERPP ;  Q663V8, SYGB_YERPS ;
DR   B1JH07, SYGB_YERPY ;  Q9FXG2, SYGC_ARATH ;  O23627, SYGM1_ARATH;
DR   Q8L785, SYGM2_ARATH;  Q9YBF8, SYG_AERPE  ;  A6TSJ4, SYG_ALKMQ  ;
DR   A8MG73, SYG_ALKOO  ;  O29346, SYG_ARCFU  ;  Q81XT3, SYG_BACAN  ;
DR   Q72YG8, SYG_BACC1  ;  Q632E8, SYG_BACCZ  ;  Q6HBZ1, SYG_BACHK  ;
DR   Q6MNT9, SYG_BDEBA  ;  Q8G7W9, SYG_BIFLO  ;  Q04451, SYG_BOMMO  ;
DR   Q0SNE2, SYG_BORAP  ;  O51344, SYG_BORBU  ;  B7J1U3, SYG_BORBZ  ;
DR   Q661P8, SYG_BORGA  ;  B2S075, SYG_BORHD  ;  Q10039, SYG_CAEEL  ;
DR   Q9PLC6, SYG_CHLMU  ;  Q9Z6W0, SYG_CHLPN  ;  B0B923, SYG_CHLT2  ;
DR   Q8KAB1, SYG_CHLTE  ;  P0CE22, SYG_CHLTR  ;  Q97EB8, SYG_CLOAB  ;
DR   A6LPL6, SYG_CLOB8  ;  B8I2Z6, SYG_CLOCE  ;  B9DY74, SYG_CLOK1  ;
DR   A5N4L2, SYG_CLOK5  ;  Q8XHL9, SYG_CLOPE  ;  A9KJ36, SYG_CLOPH  ;
DR   Q899G6, SYG_CLOTE  ;  A3DF15, SYG_CLOTH  ;  Q8FNG6, SYG_COREF  ;
DR   Q8NNC6, SYG_CORGL  ;  Q1IXM3, SYG_DEIGD  ;  Q9RSR5, SYG_DEIRA  ;
DR   Q8SQZ6, SYG_ENCCU  ;  C4Z1I4, SYG_EUBE2  ;  C4ZAV7, SYG_EUBR3  ;
DR   Q5KUC1, SYG_GEOKA  ;  A4ITQ8, SYG_GEOTN  ;  P41250, SYG_HUMAN  ;
DR   Q6AHF7, SYG_LEIXX  ;  Q04QV5, SYG_LEPBJ  ;  Q04Z62, SYG_LEPBL  ;
DR   Q72PW7, SYG_LEPIC  ;  Q8F6C0, SYG_LEPIN  ;  B1HTI6, SYG_LYSSC  ;
DR   B9E6V6, SYG_MACCJ  ;  Q6F1J8, SYG_MESFL  ;  Q57681, SYG_METJA  ;
DR   Q8TYY9, SYG_METKA  ;  A4FZX1, SYG_METM5  ;  A9A885, SYG_METM6  ;
DR   A6VIK1, SYG_METM7  ;  Q6M0Q7, SYG_METMP  ;  O27874, SYG_METTH  ;
DR   A0B5U4, SYG_METTP  ;  A6URK3, SYG_METVS  ;  Q9CZD3, SYG_MOUSE  ;
DR   P67033, SYG_MYCBO  ;  Q2SRY5, SYG_MYCCT  ;  Q7NB88, SYG_MYCGA  ;
DR   P47493, SYG_MYCGE  ;  Q6MTE4, SYG_MYCMS  ;  Q73Y21, SYG_MYCPA  ;
DR   Q8EW64, SYG_MYCPE  ;  P75425, SYG_MYCPN  ;  Q4A5V9, SYG_MYCS5  ;
DR   P67032, SYG_MYCTU  ;  A1TBP9, SYG_MYCVP  ;  Q5YZT7, SYG_NOCFA  ;
DR   Q5RBL1, SYG_PONAB  ;  Q6A964, SYG_PROAC  ;  Q9V176, SYG_PYRAB  ;
DR   Q8U0G2, SYG_PYRFU  ;  O59235, SYG_PYRHO  ;  Q5JID8, SYG_PYRKO  ;
DR   Q5I0G4, SYG_RAT    ;  Q7UEU9, SYG_RHOBA  ;  Q10179, SYG_SCHPO  ;
DR   A7X2W2, SYG_STAA1  ;  A6U237, SYG_STAA2  ;  Q2FGF8, SYG_STAA3  ;
DR   Q2FY08, SYG_STAA8  ;  A5IT93, SYG_STAA9  ;  Q2YT14, SYG_STAAB  ;
DR   Q5HFJ5, SYG_STAAC  ;  A6QHA8, SYG_STAAE  ;  P67034, SYG_STAAM  ;
DR   P99129, SYG_STAAN  ;  Q6GGD5, SYG_STAAR  ;  Q6G902, SYG_STAAS  ;
DR   A8Z4A4, SYG_STAAT  ;  P67035, SYG_STAAW  ;  B9DNL1, SYG_STACT  ;
DR   Q5HNY2, SYG_STAEQ  ;  Q8CSD5, SYG_STAES  ;  Q4L6R5, SYG_STAHJ  ;
DR   Q49Y08, SYG_STAS1  ;  Q82BR9, SYG_STRAW  ;  Q9L2H9, SYG_STRCO  ;
DR   Q47RL8, SYG_THEFY  ;  C5A1H0, SYG_THEGJ  ;  B9L0I4, SYG_THERP  ;
DR   C6A317, SYG_THESM  ;  Q72L85, SYG_THET2  ;  P56206, SYG_THET8  ;
DR   Q8RB46, SYG_THETN  ;  Q73RR5, SYG_TREDE  ;  O83678, SYG_TREPA  ;
DR   B2S3R1, SYG_TREPS  ;  B1AJD3, SYG_UREP2  ;  Q9PPZ7, SYG_UREPA  ;
DR   B5ZC00, SYG_UREU1  ;  P38088, SYG_YEAST  ;
//
ID   6.1.1.15
DE   Proline--tRNA ligase.
AN   Proline translase.
AN   Prolyl-tRNA synthetase.
CA   ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro).
PR   PROSITE; PDOC00363;
DR   Q7SIA2, SYEP_CRIGR ;  P28668, SYEP_DROME ;  P07814, SYEP_HUMAN ;
DR   Q8CGC7, SYEP_MOUSE ;  Q2IGK6, SYP1_ANADE ;  A0RHJ2, SYP1_BACAH ;
DR   Q81WL6, SYP1_BACAN ;  Q732Q0, SYP1_BACC1 ;  Q819Y4, SYP1_BACCR ;
DR   Q636K7, SYP1_BACCZ ;  Q6HEZ6, SYP1_BACHK ;  Q18CD2, SYP1_CLOD6 ;
DR   Q0S235, SYP1_RHOSR ;  Q82K46, SYP1_STRAW ;  Q2ILX2, SYP2_ANADE ;
DR   A0R9A0, SYP2_BACAH ;  Q81Z76, SYP2_BACAN ;  Q73E50, SYP2_BACC1 ;
DR   Q81IE9, SYP2_BACCR ;  Q63GI2, SYP2_BACCZ ;  Q6HNZ7, SYP2_BACHK ;
DR   Q18CD7, SYP2_CLOD6 ;  Q0SAY4, SYP2_RHOSR ;  Q82JV8, SYP2_STRAW ;
DR   P78600, SYPC_CANAL ;  Q7L3T8, SYPM_HUMAN ;  Q8CFI5, SYPM_MOUSE ;
DR   Q5M7W7, SYPM_RAT   ;  O74765, SYPM_SCHPO ;  P39965, SYPM_YEAST ;
DR   B0C230, SYP_ACAM1  ;  A1TTD0, SYP_ACIAC  ;  Q6FE23, SYP_ACIAD  ;
DR   B7GWV6, SYP_ACIB3  ;  B7I854, SYP_ACIB5  ;  B2HY33, SYP_ACIBC  ;
DR   Q1IST4, SYP_ACIBL  ;  B0VRW9, SYP_ACIBS  ;  A3M8I1, SYP_ACIBT  ;
DR   B0V4Y6, SYP_ACIBY  ;  A0LV31, SYP_ACIC1  ;  C1F3P3, SYP_ACIC5  ;
DR   A5FX26, SYP_ACICJ  ;  B9ME00, SYP_ACIET  ;  B7J4Y9, SYP_ACIF2  ;
DR   B5EKH7, SYP_ACIF5  ;  A1W4B3, SYP_ACISJ  ;  A3N3C6, SYP_ACTP2  ;
DR   B3GZ82, SYP_ACTP7  ;  B0BT03, SYP_ACTPJ  ;  A6VKR5, SYP_ACTSZ  ;
DR   A0KPA5, SYP_AERHH  ;  Q9Y9G0, SYP_AERPE  ;  A4SJ23, SYP_AERS4  ;
DR   Q8UFV9, SYP_AGRT5  ;  B2UL92, SYP_AKKM8  ;  Q0VRL1, SYP_ALCBS  ;
DR   Q0AB94, SYP_ALHEH  ;  B6EHZ8, SYP_ALISL  ;  A6TL31, SYP_ALKMQ  ;
DR   A8MLB3, SYP_ALKOO  ;  B4RV73, SYP_ALTMD  ;  B3ER64, SYP_AMOA5  ;
DR   B8J9M0, SYP_ANAD2  ;  A7H7J7, SYP_ANADF  ;  Q5PAZ5, SYP_ANAMM  ;
DR   Q2GK70, SYP_ANAPZ  ;  B4UGI0, SYP_ANASK  ;  B9MPD7, SYP_ANATD  ;
DR   Q3MAQ7, SYP_ANAVT  ;  O66690, SYP_AQUAE  ;  A8ERT9, SYP_ARCB4  ;
DR   O28664, SYP_ARCFU  ;  Q5P7T1, SYP_AROAE  ;  A1R508, SYP_ARTAT  ;
DR   A0JUT1, SYP_ARTS2  ;  Q2NJ01, SYP_AYWBP  ;  A8I438, SYP_AZOC5  ;
DR   B6YQ92, SYP_AZOPC  ;  A1K976, SYP_AZOSB  ;  C1DRG4, SYP_AZOVD  ;
DR   A7Z4S8, SYP_BACA2  ;  C3P5M1, SYP_BACAA  ;  C3L7A8, SYP_BACAC  ;
DR   B7JJ97, SYP_BACC0  ;  B7IUH7, SYP_BACC2  ;  C1EP43, SYP_BACC3  ;
DR   B7HDU2, SYP_BACC4  ;  B7HLF2, SYP_BACC7  ;  A7GRE9, SYP_BACCN  ;
DR   B9IVA8, SYP_BACCQ  ;  Q5LCF0, SYP_BACFN  ;  Q64TJ6, SYP_BACFR  ;
DR   Q9KA71, SYP_BACHD  ;  Q65JJ1, SYP_BACLD  ;  A8FDC1, SYP_BACP2  ;
DR   Q5WFT6, SYP_BACSK  ;  O31755, SYP_BACSU  ;  Q8A988, SYP_BACTN  ;
DR   A6L5I2, SYP_BACV8  ;  A9VT57, SYP_BACWK  ;  A1USY3, SYP_BARBK  ;
DR   Q6G3A4, SYP_BARHE  ;  Q6FZX5, SYP_BARQU  ;  A9IUL1, SYP_BART1  ;
DR   Q1LSM8, SYP_BAUCH  ;  Q6MIW2, SYP_BDEBA  ;  B2IDI9, SYP_BEII9  ;
DR   B8DTM3, SYP_BIFA0  ;  A1A0K4, SYP_BIFAA  ;  Q8G3N0, SYP_BIFLO  ;
DR   Q7VRC8, SYP_BLOFL  ;  Q493B4, SYP_BLOPB  ;  Q2KVA0, SYP_BORA1  ;
DR   Q0SNA5, SYP_BORAP  ;  Q7WFN9, SYP_BORBR  ;  O51363, SYP_BORBU  ;
DR   B7J1X2, SYP_BORBZ  ;  Q661L6, SYP_BORGA  ;  Q7W481, SYP_BORPA  ;
DR   A9I4I5, SYP_BORPD  ;  Q7VTZ8, SYP_BORPE  ;  C0QY98, SYP_BRAHW  ;
DR   Q89KM8, SYP_BRAJA  ;  A5EK68, SYP_BRASB  ;  A4YVI0, SYP_BRASO  ;
DR   C0ZF57, SYP_BREBN  ;  B2S561, SYP_BRUA1  ;  Q2YNE3, SYP_BRUA2  ;
DR   Q57DT1, SYP_BRUAB  ;  A9MAJ9, SYP_BRUC2  ;  C0RIF7, SYP_BRUMB  ;
DR   Q8YGL8, SYP_BRUME  ;  A5VQ02, SYP_BRUO2  ;  B0CLE9, SYP_BRUSI  ;
DR   Q8G197, SYP_BRUSU  ;  B8D937, SYP_BUCA5  ;  P57333, SYP_BUCAI  ;
DR   Q8K9S2, SYP_BUCAP  ;  B8D7E1, SYP_BUCAT  ;  Q89AN7, SYP_BUCBP  ;
DR   B1YSV1, SYP_BURA4  ;  Q1BZD6, SYP_BURCA  ;  B1JVA5, SYP_BURCC  ;
DR   A0K4B4, SYP_BURCH  ;  B4E5W6, SYP_BURCJ  ;  Q0BIH4, SYP_BURCM  ;
DR   A9AI56, SYP_BURM1  ;  A3MR95, SYP_BURM7  ;  A2S5R3, SYP_BURM9  ;
DR   Q62GV8, SYP_BURMA  ;  A1V0N6, SYP_BURMS  ;  A3NZI6, SYP_BURP0  ;
DR   Q3JNG4, SYP_BURP1  ;  A3NDS2, SYP_BURP6  ;  B2JHD3, SYP_BURP8  ;
DR   B2SYU8, SYP_BURPP  ;  Q63QM5, SYP_BURPS  ;  Q39JU3, SYP_BURS3  ;
DR   Q2SZF6, SYP_BURTA  ;  A4JBC2, SYP_BURVG  ;  Q13U19, SYP_BURXL  ;
DR   A8MC04, SYP_CALMQ  ;  A4XHN7, SYP_CALS8  ;  A7ZD35, SYP_CAMC1  ;
DR   A7GYU6, SYP_CAMC5  ;  A0RNT1, SYP_CAMFF  ;  A7I1R8, SYP_CAMHC  ;
DR   A8FKW6, SYP_CAMJ8  ;  A7H4J9, SYP_CAMJD  ;  Q9PHX1, SYP_CAMJE  ;
DR   A1VYQ2, SYP_CAMJJ  ;  Q5HVM3, SYP_CAMJR  ;  B9KGB1, SYP_CAMLR  ;
DR   Q3AB89, SYP_CARHZ  ;  B8GWT1, SYP_CAUCN  ;  Q9A6Z5, SYP_CAUCR  ;
DR   B0SZ28, SYP_CAUSK  ;  A0RUI8, SYP_CENSY  ;  A9W9Q2, SYP_CHLAA  ;
DR   Q5L6M5, SYP_CHLAB  ;  B8G3V5, SYP_CHLAD  ;  Q3ASP3, SYP_CHLCH  ;
DR   Q824A9, SYP_CHLCV  ;  Q253K4, SYP_CHLFF  ;  B3EE36, SYP_CHLL2  ;
DR   Q9PK01, SYP_CHLMU  ;  B3QPX3, SYP_CHLP8  ;  B3EP23, SYP_CHLPB  ;
DR   A1BHL6, SYP_CHLPD  ;  Q9Z851, SYP_CHLPN  ;  B9LC55, SYP_CHLSY  ;
DR   B0B7W3, SYP_CHLT2  ;  B3QYP1, SYP_CHLT3  ;  Q3KLW0, SYP_CHLTA  ;
DR   B0BC28, SYP_CHLTB  ;  Q8KCD1, SYP_CHLTE  ;  P36431, SYP_CHLTR  ;
DR   Q1QVL8, SYP_CHRSD  ;  Q7P0J3, SYP_CHRVO  ;  A8AL94, SYP_CITK8  ;
DR   A5CSZ7, SYP_CLAM3  ;  B0RDZ1, SYP_CLAMS  ;  Q97ED5, SYP_CLOAB  ;
DR   A7FYU0, SYP_CLOB1  ;  C3KUV8, SYP_CLOB6  ;  A6LPP0, SYP_CLOB8  ;
DR   B2UY89, SYP_CLOBA  ;  B2TIF5, SYP_CLOBB  ;  A5I768, SYP_CLOBH  ;
DR   C1FM10, SYP_CLOBJ  ;  B1IFI2, SYP_CLOBK  ;  A7GIT0, SYP_CLOBL  ;
DR   B1L224, SYP_CLOBM  ;  B8I5R4, SYP_CLOCE  ;  A0Q2I3, SYP_CLONN  ;
DR   Q0TMM3, SYP_CLOP1  ;  Q8XHQ4, SYP_CLOPE  ;  A9KL35, SYP_CLOPH  ;
DR   Q0SQC0, SYP_CLOPS  ;  Q9L4Q8, SYP_CLOSD  ;  Q890M2, SYP_CLOTE  ;
DR   A3DJL6, SYP_CLOTH  ;  Q47Z50, SYP_COLP3  ;  B5Y8J7, SYP_COPPD  ;
DR   C3PH25, SYP_CORA7  ;  Q6NGM7, SYP_CORDI  ;  Q8FP97, SYP_COREF  ;
DR   A4QF01, SYP_CORGB  ;  Q8NP31, SYP_CORGL  ;  Q4JV46, SYP_CORJK  ;
DR   B1VGB6, SYP_CORU7  ;  A9KGU5, SYP_COXBN  ;  A9N9Z2, SYP_COXBR  ;
DR   Q83F67, SYP_COXBU  ;  Q0K6Q0, SYP_CUPNH  ;  Q46X21, SYP_CUPPJ  ;
DR   B3R894, SYP_CUPTR  ;  B8HNJ7, SYP_CYAP4  ;  B7K9K1, SYP_CYAP7  ;
DR   B7K1H5, SYP_CYAP8  ;  Q11Q45, SYP_CYTH3  ;  Q47ID0, SYP_DECAR  ;
DR   Q3Z9I5, SYP_DEHE1  ;  A5FS84, SYP_DEHSB  ;  Q3ZZD0, SYP_DEHSC  ;
DR   Q1J0W2, SYP_DEIGD  ;  Q9RUW4, SYP_DEIRA  ;  A9BP65, SYP_DELAS  ;
DR   C6BYX7, SYP_DESAD  ;  B1I2J1, SYP_DESAP  ;  B8IZD1, SYP_DESDA  ;
DR   Q30Z93, SYP_DESDG  ;  B8FR28, SYP_DESHD  ;  Q24UG7, SYP_DESHY  ;
DR   C4XTD0, SYP_DESMR  ;  Q6AP31, SYP_DESPS  ;  A4J5Y2, SYP_DESRM  ;
DR   Q72CD8, SYP_DESVH  ;  B8DNM5, SYP_DESVM  ;  A1VE74, SYP_DESVV  ;
DR   A5EXK9, SYP_DICNV  ;  A8LQU6, SYP_DINSH  ;  A7ZHT6, SYP_ECO24  ;
DR   B7UJ96, SYP_ECO27  ;  B7MBH6, SYP_ECO45  ;  B7LHA4, SYP_ECO55  ;
DR   Q8X8W2, SYP_ECO57  ;  B5Z0H4, SYP_ECO5E  ;  B7NKX8, SYP_ECO7I  ;
DR   B7MP55, SYP_ECO81  ;  B7M1Z9, SYP_ECO8A  ;  C4ZRT7, SYP_ECOBW  ;
DR   B1XD64, SYP_ECODH  ;  A7ZWE2, SYP_ECOHS  ;  A1A7N8, SYP_ECOK1  ;
DR   Q0TLD7, SYP_ECOL5  ;  Q8FKZ4, SYP_ECOL6  ;  B1IQE6, SYP_ECOLC  ;
DR   P16659, SYP_ECOLI  ;  B7N862, SYP_ECOLU  ;  B6HZR3, SYP_ECOSE  ;
DR   B1LGZ7, SYP_ECOSM  ;  Q1RFZ4, SYP_ECOUT  ;  C5B780, SYP_EDWI9  ;
DR   Q3YSD4, SYP_EHRCJ  ;  Q2GG92, SYP_EHRCR  ;  Q5FHL5, SYP_EHRRG  ;
DR   Q5HBI6, SYP_EHRRW  ;  B2KCB2, SYP_ELUMP  ;  Q8SSD7, SYP_ENCCU  ;
DR   A4W6T9, SYP_ENT38  ;  Q831W7, SYP_ENTFA  ;  A7MI22, SYP_ENTS8  ;
DR   Q6D1B9, SYP_ERWCT  ;  B2VDZ9, SYP_ERWT9  ;  Q2NAH8, SYP_ERYLH  ;
DR   B7LW79, SYP_ESCF3  ;  C4Z1D7, SYP_EUBE2  ;  C4ZC24, SYP_EUBR3  ;
DR   B1YI68, SYP_EXIS2  ;  A7HKV2, SYP_FERNB  ;  B0RZJ0, SYP_FINM2  ;
DR   A5FA31, SYP_FLAJ1  ;  A6GZF3, SYP_FLAPJ  ;  Q0RBM4, SYP_FRAAA  ;
DR   B0TXX4, SYP_FRAP2  ;  Q2J529, SYP_FRASC  ;  Q14GJ0, SYP_FRAT1  ;
DR   A7NB07, SYP_FRATF  ;  Q2A4E9, SYP_FRATH  ;  B2SFQ6, SYP_FRATM  ;
DR   A0Q7N3, SYP_FRATN  ;  Q0BMT1, SYP_FRATO  ;  Q5NF37, SYP_FRATT  ;
DR   A4IWT9, SYP_FRATW  ;  Q8RIE2, SYP_FUSNN  ;  B5EIT9, SYP_GEOBB  ;
DR   Q5L0J4, SYP_GEOKA  ;  B3E1X5, SYP_GEOLS  ;  Q39VY6, SYP_GEOMG  ;
DR   B9LZK1, SYP_GEOSF  ;  Q74D59, SYP_GEOSL  ;  C6E496, SYP_GEOSM  ;
DR   C5D9C3, SYP_GEOSW  ;  A4IMD1, SYP_GEOTN  ;  Q7NHL0, SYP_GLOVI  ;
DR   Q5FUU9, SYP_GLUOX  ;  Q0BSM0, SYP_GRABC  ;  A0M4Z3, SYP_GRAFK  ;
DR   Q7VKI5, SYP_HAEDU  ;  Q4QMG5, SYP_HAEI8  ;  A5UDZ4, SYP_HAEIE  ;
DR   A5UHN3, SYP_HAEIG  ;  P43830, SYP_HAEIN  ;  B8F7C2, SYP_HAEPS  ;
DR   Q0I4S8, SYP_HAES1  ;  B0UWK9, SYP_HAES2  ;  Q2SD07, SYP_HAHCH  ;
DR   A1WUX1, SYP_HALHL  ;  B9LUM0, SYP_HALLT  ;  Q5V5H0, SYP_HALMA  ;
DR   B8CW65, SYP_HALOH  ;  B0R3A3, SYP_HALS3  ;  Q9HS52, SYP_HALSA  ;
DR   Q18JG3, SYP_HALWD  ;  C4K3K4, SYP_HAMD5  ;  Q17W62, SYP_HELAH  ;
DR   Q7VFF0, SYP_HELHP  ;  B0THP0, SYP_HELMI  ;  B6JKG9, SYP_HELP2  ;
DR   B5ZA05, SYP_HELPG  ;  Q1CUR4, SYP_HELPH  ;  Q9ZMJ6, SYP_HELPJ  ;
DR   B2US70, SYP_HELPS  ;  P56124, SYP_HELPY  ;  A9B562, SYP_HERA2  ;
DR   A4G8R0, SYP_HERAR  ;  B4U8B2, SYP_HYDS0  ;  Q0C1C5, SYP_HYPNA  ;
DR   Q5QW31, SYP_IDILO  ;  A8A9E3, SYP_IGNH4  ;  A6T2D1, SYP_JANMA  ;
DR   Q28TI5, SYP_JANSC  ;  A6W7Y5, SYP_KINRD  ;  B5Y1H7, SYP_KLEP3  ;
DR   A6T4Z7, SYP_KLEP7  ;  B2GKS1, SYP_KOCRD  ;  C5CFP9, SYP_KOSOT  ;
DR   Q5FJN0, SYP_LACAC  ;  Q03QS8, SYP_LACBA  ;  Q038L9, SYP_LACC3  ;
DR   Q1G9P3, SYP_LACDA  ;  Q049U9, SYP_LACDB  ;  B2GBM5, SYP_LACF3  ;
DR   Q044C3, SYP_LACGA  ;  A8YVR3, SYP_LACH4  ;  Q74IS2, SYP_LACJO  ;
DR   Q9CDT4, SYP_LACLA  ;  A2RNT2, SYP_LACLM  ;  Q02VZ7, SYP_LACLS  ;
DR   Q88VK1, SYP_LACPL  ;  A5VJD4, SYP_LACRD  ;  B2G6V0, SYP_LACRJ  ;
DR   Q1WUG0, SYP_LACS1  ;  Q38W72, SYP_LACSS  ;  Q1MRD0, SYP_LAWIP  ;
DR   Q5X756, SYP_LEGPA  ;  A5IGL5, SYP_LEGPC  ;  Q5ZXN7, SYP_LEGPH  ;
DR   Q5WYK5, SYP_LEGPL  ;  Q6AEX8, SYP_LEIXX  ;  B0SDM9, SYP_LEPBA  ;
DR   Q04U64, SYP_LEPBJ  ;  Q053M7, SYP_LEPBL  ;  B0SM58, SYP_LEPBP  ;
DR   B1XYW5, SYP_LEPCP  ;  Q72U06, SYP_LEPIC  ;  Q8F148, SYP_LEPIN  ;
DR   B1MY62, SYP_LEUCK  ;  Q03YC4, SYP_LEUMM  ;  Q92C35, SYP_LISIN  ;
DR   C1L2M5, SYP_LISMC  ;  Q720A3, SYP_LISMF  ;  B8DG08, SYP_LISMH  ;
DR   Q8Y7G2, SYP_LISMO  ;  A0AIC0, SYP_LISW6  ;  B1HQZ9, SYP_LYSSC  ;
DR   B9EBE4, SYP_MACCJ  ;  Q2W136, SYP_MAGSA  ;  A0L8I2, SYP_MAGSM  ;
DR   Q65QU0, SYP_MANSM  ;  A1U1F0, SYP_MARAV  ;  Q0APX0, SYP_MARMM  ;
DR   A6VXT1, SYP_MARMS  ;  Q6F0Y9, SYP_MESFL  ;  Q11JI8, SYP_MESSB  ;
DR   A6UTK4, SYP_META3  ;  Q8TJA2, SYP_METAC  ;  A7I9R7, SYP_METB6  ;
DR   Q46G28, SYP_METBF  ;  Q12ZC6, SYP_METBU  ;  B7KPK1, SYP_METC4  ;
DR   Q606K3, SYP_METCA  ;  A9W1L5, SYP_METEP  ;  Q1H497, SYP_METFK  ;
DR   Q2FLY5, SYP_METHJ  ;  Q58635, SYP_METJA  ;  Q8TW09, SYP_METKA  ;
DR   A2ST96, SYP_METLZ  ;  A4FYA4, SYP_METM5  ;  A9A787, SYP_METM6  ;
DR   A6VK03, SYP_METM7  ;  Q8PYZ1, SYP_METMA  ;  A3CX68, SYP_METMJ  ;
DR   Q6LZD3, SYP_METMP  ;  B8IUW4, SYP_METNO  ;  B1ZA28, SYP_METPB  ;
DR   A2SD40, SYP_METPP  ;  B1LUL8, SYP_METRJ  ;  A5UJW4, SYP_METS3  ;
DR   B0ULM2, SYP_METS4  ;  A4YI09, SYP_METS5  ;  B8EP84, SYP_METSB  ;
DR   Q2NFL1, SYP_METST  ;  O26708, SYP_METTH  ;  A0B9N3, SYP_METTP  ;
DR   A6USJ4, SYP_METVS  ;  B0JTD7, SYP_MICAN  ;  C5C9S6, SYP_MICLC  ;
DR   Q2RJN1, SYP_MOOTA  ;  A0QIY9, SYP_MYCA1  ;  B1MD96, SYP_MYCA9  ;
DR   Q7TXQ5, SYP_MYCBO  ;  A1KMI8, SYP_MYCBP  ;  Q2SSG0, SYP_MYCCT  ;
DR   Q7NBP5, SYP_MYCGA  ;  P47525, SYP_MYCGE  ;  Q600Q7, SYP_MYCH2  ;
DR   Q4A7Y3, SYP_MYCH7  ;  Q4A9V2, SYP_MYCHJ  ;  B8ZRT2, SYP_MYCLB  ;
DR   Q9Z5I7, SYP_MYCLE  ;  Q6KIE6, SYP_MYCMO  ;  Q6MTR9, SYP_MYCMS  ;
DR   Q73VU8, SYP_MYCPA  ;  Q8EUW7, SYP_MYCPE  ;  P75382, SYP_MYCPN  ;
DR   Q98R27, SYP_MYCPU  ;  A0QVM0, SYP_MYCS2  ;  Q4A5S0, SYP_MYCS5  ;
DR   A1UER2, SYP_MYCSK  ;  Q1BAA0, SYP_MYCSS  ;  O05814, SYP_MYCTU  ;
DR   A0PQB8, SYP_MYCUA  ;  A1T7H2, SYP_MYCVP  ;  Q1CXV1, SYP_MYXXD  ;
DR   Q74ND5, SYP_NANEQ  ;  Q3IS99, SYP_NATPD  ;  B2A5T8, SYP_NATTJ  ;
DR   B9LA07, SYP_NAUPA  ;  Q5F938, SYP_NEIG1  ;  Q9JU09, SYP_NEIMA  ;
DR   Q9JZ14, SYP_NEIMB  ;  A1KUG4, SYP_NEIMF  ;  Q2GE40, SYP_NEOSM  ;
DR   Q0AGN2, SYP_NITEC  ;  Q82UZ8, SYP_NITEU  ;  Q1QLA8, SYP_NITHX  ;
DR   Q2YBW3, SYP_NITMU  ;  Q3JCN7, SYP_NITOC  ;  A6Q3S4, SYP_NITSB  ;
DR   Q3SRG6, SYP_NITWN  ;  Q5YSB9, SYP_NOCFA  ;  A1SLL4, SYP_NOCSJ  ;
DR   B2J707, SYP_NOSP7  ;  Q8YM83, SYP_NOSS1  ;  Q2G6Y3, SYP_NOVAD  ;
DR   Q8ESQ5, SYP_OCEIH  ;  A6X1L5, SYP_OCHA4  ;  Q04F81, SYP_OENOB  ;
DR   B6JH58, SYP_OLICO  ;  Q6YQX7, SYP_ONYPE  ;  A6LAP3, SYP_PARD8  ;
DR   A1B1L0, SYP_PARDP  ;  A7HY28, SYP_PARL1  ;  Q6MBK1, SYP_PARUW  ;
DR   Q9CL72, SYP_PASMU  ;  C6DDF6, SYP_PECCP  ;  Q03FS9, SYP_PEDPA  ;
DR   Q3A6R6, SYP_PELCD  ;  Q3B2T0, SYP_PELLD  ;  B4SG51, SYP_PELPB  ;
DR   A1APU5, SYP_PELPD  ;  A5D2U6, SYP_PELTS  ;  Q4FM73, SYP_PELUB  ;
DR   C0QTI8, SYP_PERMH  ;  A9BGA8, SYP_PETMO  ;  B4RBZ9, SYP_PHEZH  ;
DR   Q7N8M7, SYP_PHOLL  ;  Q6LN48, SYP_PHOPR  ;  B1VAN9, SYP_PHYAS  ;
DR   Q6KZA3, SYP_PICTO  ;  Q8I5R7, SYP_PLAF7  ;  A1VK86, SYP_POLNA  ;
DR   B1XT38, SYP_POLNS  ;  Q12FA3, SYP_POLSJ  ;  A4SVA7, SYP_POLSQ  ;
DR   B2RJG1, SYP_PORG3  ;  Q7MVS7, SYP_PORGI  ;  B4S9D5, SYP_PROA2  ;
DR   Q6A7L9, SYP_PROAC  ;  A3PBN3, SYP_PROM0  ;  A2C0W8, SYP_PROM1  ;
DR   A8G3M4, SYP_PROM2  ;  A2C7N5, SYP_PROM3  ;  A9BED0, SYP_PROM4  ;
DR   A2BVH0, SYP_PROM5  ;  Q31C25, SYP_PROM9  ;  Q7VD75, SYP_PROMA  ;
DR   B4F249, SYP_PROMH  ;  Q7TUU4, SYP_PROMM  ;  Q7V2H0, SYP_PROMP  ;
DR   A2BPZ0, SYP_PROMS  ;  Q46GR7, SYP_PROMT  ;  A4SFS0, SYP_PROVI  ;
DR   Q48FB4, SYP_PSE14  ;  Q15WD6, SYP_PSEA6  ;  A6VA16, SYP_PSEA7  ;
DR   B7UXX6, SYP_PSEA8  ;  Q02IB8, SYP_PSEAB  ;  Q9I502, SYP_PSEAE  ;
DR   Q1I6D7, SYP_PSEE4  ;  Q4KH98, SYP_PSEF5  ;  Q3IGT7, SYP_PSEHT  ;
DR   A4XRQ7, SYP_PSEMY  ;  A5VZT5, SYP_PSEP1  ;  Q3KH16, SYP_PSEPF  ;
DR   B0KTK4, SYP_PSEPG  ;  Q88NK2, SYP_PSEPK  ;  B1JD82, SYP_PSEPW  ;
DR   Q87Y24, SYP_PSESM  ;  Q4ZWM2, SYP_PSEU2  ;  A4VNB4, SYP_PSEU5  ;
DR   Q4FUL6, SYP_PSYA2  ;  Q1QDK7, SYP_PSYCK  ;  A1SZR1, SYP_PSYIN  ;
DR   A5WDG2, SYP_PSYWF  ;  Q9V022, SYP_PYRAB  ;  Q8ZVQ9, SYP_PYRAE  ;
DR   A4WJ22, SYP_PYRAR  ;  A3MV50, SYP_PYRCJ  ;  Q8U1C4, SYP_PYRFU  ;
DR   O58734, SYP_PYRHO  ;  A1RSR6, SYP_PYRIL  ;  Q5JF49, SYP_PYRKO  ;
DR   Q1LIQ4, SYP_RALME  ;  B2UCU9, SYP_RALPJ  ;  Q8XVL4, SYP_RALSO  ;
DR   B3PW17, SYP_RHIE6  ;  Q2K9R4, SYP_RHIEC  ;  Q1MIJ6, SYP_RHIL3  ;
DR   Q98KS5, SYP_RHILO  ;  B5ZYN2, SYP_RHILW  ;  Q92QN2, SYP_RHIME  ;
DR   Q7UGJ7, SYP_RHOBA  ;  C0ZY88, SYP_RHOE4  ;  Q21YZ5, SYP_RHOFD  ;
DR   C1B2Z4, SYP_RHOOB  ;  Q2IWW0, SYP_RHOP2  ;  Q07NK2, SYP_RHOP5  ;
DR   Q6N5P6, SYP_RHOPA  ;  Q215F8, SYP_RHOPB  ;  Q135Z6, SYP_RHOPS  ;
DR   B3Q7L2, SYP_RHOPT  ;  Q2RU19, SYP_RHORT  ;  A3PMH0, SYP_RHOS1  ;
DR   Q3IZS9, SYP_RHOS4  ;  A4WPJ3, SYP_RHOS5  ;  B9KLX3, SYP_RHOSK  ;
DR   C3PNA1, SYP_RICAE  ;  A8GN90, SYP_RICAH  ;  A8GU77, SYP_RICB8  ;
DR   Q1RIC9, SYP_RICBR  ;  A8EZ51, SYP_RICCK  ;  Q92I92, SYP_RICCN  ;
DR   Q4ULX2, SYP_RICFE  ;  Q9ZDE7, SYP_RICPR  ;  C4K2D7, SYP_RICPU  ;
DR   B0BXB9, SYP_RICRO  ;  A8GRW1, SYP_RICRS  ;  Q68WZ3, SYP_RICTY  ;
DR   A7NKX0, SYP_ROSCS  ;  Q168E6, SYP_ROSDO  ;  A5UU62, SYP_ROSS1  ;
DR   Q1AX25, SYP_RUBXD  ;  A1AW17, SYP_RUTMC  ;  Q21MA8, SYP_SACD2  ;
DR   B5F8V6, SYP_SALA4  ;  A8LYE7, SYP_SALAI  ;  A9MPG5, SYP_SALAR  ;
DR   Q57T14, SYP_SALCH  ;  B5FJ42, SYP_SALDC  ;  B5R434, SYP_SALEP  ;
DR   B5R5J8, SYP_SALG2  ;  B4TK70, SYP_SALHS  ;  B4SV24, SYP_SALNS  ;
DR   Q5PD80, SYP_SALPA  ;  A9N0U7, SYP_SALPB  ;  C0Q6L7, SYP_SALPC  ;
DR   B5BAQ2, SYP_SALPK  ;  Q2RZJ2, SYP_SALRD  ;  B4TYF5, SYP_SALSV  ;
DR   Q8XEY9, SYP_SALTI  ;  A4X5V6, SYP_SALTO  ;  Q7CR62, SYP_SALTY  ;
DR   A8GIB4, SYP_SERP5  ;  A1S4R2, SYP_SHEAM  ;  B8EDD0, SYP_SHEB2  ;
DR   A3D6H7, SYP_SHEB5  ;  A6WQB8, SYP_SHEB8  ;  A9KVR8, SYP_SHEB9  ;
DR   Q12L53, SYP_SHEDO  ;  Q07ZH1, SYP_SHEFN  ;  B0TNJ5, SYP_SHEHH  ;
DR   A3QG64, SYP_SHELP  ;  Q8ECI8, SYP_SHEON  ;  A8H6J5, SYP_SHEPA  ;
DR   A4Y8F6, SYP_SHEPC  ;  A0KV13, SYP_SHESA  ;  Q0HKJ4, SYP_SHESM  ;
DR   Q0HWU6, SYP_SHESR  ;  A1RI33, SYP_SHESW  ;  B1KNR3, SYP_SHEWM  ;
DR   B2U338, SYP_SHIB3  ;  Q325U6, SYP_SHIBS  ;  Q32JR3, SYP_SHIDS  ;
DR   Q0T815, SYP_SHIF8  ;  Q83MC8, SYP_SHIFL  ;  Q3Z5G3, SYP_SHISS  ;
DR   Q5LUD3, SYP_SILPO  ;  Q1GFI1, SYP_SILST  ;  A6U7Z3, SYP_SINMW  ;
DR   Q2NRN0, SYP_SODGM  ;  Q027I0, SYP_SOLUE  ;  Q1GTS7, SYP_SPHAL  ;
DR   Q7X2P1, SYP_SPHEL  ;  A5V8U0, SYP_SPHWW  ;  A7X1P3, SYP_STAA1  ;
DR   A6U182, SYP_STAA2  ;  Q2FHH5, SYP_STAA3  ;  Q2G1Z4, SYP_STAA8  ;
DR   A5ISE7, SYP_STAA9  ;  Q2YXK5, SYP_STAAB  ;  Q5HGG8, SYP_STAAC  ;
DR   A6QGG3, SYP_STAAE  ;  Q99UK9, SYP_STAAM  ;  Q7A5Y3, SYP_STAAN  ;
DR   Q6GHH2, SYP_STAAR  ;  Q6G9V0, SYP_STAAS  ;  A8Z3U3, SYP_STAAT  ;
DR   Q7A120, SYP_STAAW  ;  Q5HPS8, SYP_STAEQ  ;  Q8CST7, SYP_STAES  ;
DR   Q4L5W5, SYP_STAHJ  ;  Q49X48, SYP_STAS1  ;  Q3JZ37, SYP_STRA1  ;
DR   Q8E362, SYP_STRA3  ;  Q8DXD8, SYP_STRA5  ;  Q9KYR6, SYP_STRCO  ;
DR   C0M9E6, SYP_STRE4  ;  A8AZA7, SYP_STRGC  ;  B1VYP2, SYP_STRGG  ;
DR   B4SJ64, SYP_STRM5  ;  B2FMR5, SYP_STRMK  ;  Q8DSJ9, SYP_STRMU  ;
DR   Q99XY4, SYP_STRP1  ;  Q04MI4, SYP_STRP2  ;  P0DG54, SYP_STRP3  ;
DR   B5E6T8, SYP_STRP4  ;  Q5X9U7, SYP_STRP6  ;  C1CB39, SYP_STRP7  ;
DR   Q8NZB4, SYP_STRP8  ;  Q1J9R3, SYP_STRPB  ;  Q1JJW2, SYP_STRPC  ;
DR   Q1JEV3, SYP_STRPD  ;  Q1J4L9, SYP_STRPF  ;  A2RGI4, SYP_STRPG  ;
DR   B1I8Z1, SYP_STRPI  ;  B8ZKT3, SYP_STRPJ  ;  Q48R89, SYP_STRPM  ;
DR   Q97SR1, SYP_STRPN  ;  P0DG55, SYP_STRPQ  ;  B2ISI9, SYP_STRPS  ;
DR   B5XIL5, SYP_STRPZ  ;  Q8DRB0, SYP_STRR6  ;  A4W435, SYP_STRS2  ;
DR   C0MFA1, SYP_STRS7  ;  A3CQI5, SYP_STRSV  ;  A4VXT8, SYP_STRSY  ;
DR   Q5M1N3, SYP_STRT1  ;  Q5M674, SYP_STRT2  ;  Q03MK9, SYP_STRTD  ;
DR   B9DTD1, SYP_STRU0  ;  C1CC55, SYP_STRZJ  ;  C1CIE5, SYP_STRZP  ;
DR   C1CPD8, SYP_STRZT  ;  Q4J8L4, SYP_SULAC  ;  Q30S93, SYP_SULDN  ;
DR   C3N6D0, SYP_SULIA  ;  C4KHU5, SYP_SULIK  ;  C3MQL0, SYP_SULIL  ;
DR   C3MW88, SYP_SULIM  ;  C3NGV6, SYP_SULIN  ;  C3NET8, SYP_SULIY  ;
DR   A6Q7Y7, SYP_SULNB  ;  Q9UWX2, SYP_SULSO  ;  B2V6W5, SYP_SULSY  ;
DR   Q971B5, SYP_SULTO  ;  Q67PA6, SYP_SYMTH  ;  Q2LTR7, SYP_SYNAS  ;
DR   Q31LT0, SYP_SYNE7  ;  A0LHQ7, SYP_SYNFM  ;  Q2JSB6, SYP_SYNJA  ;
DR   Q2JMD8, SYP_SYNJB  ;  B1XP53, SYP_SYNP2  ;  Q5N044, SYP_SYNP6  ;
DR   A5GJD3, SYP_SYNPW  ;  Q7U5D6, SYP_SYNPX  ;  A5GSC0, SYP_SYNR3  ;
DR   Q0I8J8, SYP_SYNS3  ;  Q3AWR9, SYP_SYNS9  ;  Q3ALR5, SYP_SYNSC  ;
DR   Q0AYJ4, SYP_SYNWW  ;  P73942, SYP_SYNY3  ;  C5BPN9, SYP_TERTT  ;
DR   B7IFB6, SYP_THEAB  ;  Q9HJN0, SYP_THEAC  ;  Q8DKT0, SYP_THEEB  ;
DR   Q47RV7, SYP_THEFY  ;  A8F3T2, SYP_THELT  ;  A6LJ40, SYP_THEM4  ;
DR   Q9WYY4, SYP_THEMA  ;  B9KBD7, SYP_THENN  ;  B1Y963, SYP_THENV  ;
DR   A5IJQ9, SYP_THEP1  ;  B0KCH5, SYP_THEP3  ;  A1RYD8, SYP_THEPD  ;
DR   B0K5F2, SYP_THEPX  ;  B1L8Y1, SYP_THESQ  ;  Q72GF9, SYP_THET2  ;
DR   Q5SM28, SYP_THET8  ;  Q8R7S9, SYP_THETN  ;  Q979Q5, SYP_THEVO  ;
DR   B5YKW0, SYP_THEYD  ;  Q31GQ3, SYP_THICR  ;  Q3SH24, SYP_THIDA  ;
DR   B8GPP4, SYP_THISH  ;  C4LBX6, SYP_TOLAT  ;  Q73KJ8, SYP_TREDE  ;
DR   O83195, SYP_TREPA  ;  B2S2A7, SYP_TREPS  ;  Q116D3, SYP_TRIEI  ;
DR   Q83HI1, SYP_TROW8  ;  Q83GR4, SYP_TROWT  ;  Q0W0C9, SYP_UNCMA  ;
DR   B1H063, SYP_UNCTG  ;  B1AJ93, SYP_UREP2  ;  Q9PQ38, SYP_UREPA  ;
DR   B5ZBT9, SYP_UREU1  ;  C5CXW9, SYP_VARPS  ;  A1WKI1, SYP_VEREI  ;
DR   A5CX68, SYP_VESOH  ;  A5F340, SYP_VIBC3  ;  Q9KTM7, SYP_VIBCH  ;
DR   C3LTC5, SYP_VIBCM  ;  Q5E719, SYP_VIBF1  ;  B5FBD6, SYP_VIBFM  ;
DR   A7N1W0, SYP_VIBHB  ;  Q87MC3, SYP_VIBPA  ;  B7VIT2, SYP_VIBSL  ;
DR   Q8DBH9, SYP_VIBVU  ;  Q7MIE5, SYP_VIBVY  ;  Q8D1V9, SYP_WIGBR  ;
DR   Q73GW6, SYP_WOLPM  ;  Q7M8L1, SYP_WOLSU  ;  Q5GTK5, SYP_WOLTR  ;
DR   C0R3N5, SYP_WOLWR  ;  Q8PGP9, SYP_XANAC  ;  Q3BP90, SYP_XANC5  ;
DR   Q4UQN5, SYP_XANC8  ;  B0RVJ2, SYP_XANCB  ;  Q8PCS4, SYP_XANCP  ;
DR   Q2P7I5, SYP_XANOM  ;  B2SPG9, SYP_XANOP  ;  Q5H4Q7, SYP_XANOR  ;
DR   A7INT8, SYP_XANP2  ;  B2I7W6, SYP_XYLF2  ;  Q9PG57, SYP_XYLFA  ;
DR   B0U4A7, SYP_XYLFM  ;  Q87B25, SYP_XYLFT  ;  A1JP53, SYP_YERE8  ;
DR   A7FFJ4, SYP_YERP3  ;  Q1CAK9, SYP_YERPA  ;  B2JZ09, SYP_YERPB  ;
DR   Q7CH25, SYP_YERPE  ;  A9R371, SYP_YERPG  ;  Q1CFH2, SYP_YERPN  ;
DR   A4TL66, SYP_YERPP  ;  Q667L4, SYP_YERPS  ;  B1JQI5, SYP_YERPY  ;
DR   P75000, SYP_ZYMMO  ;  P38708, YHI0_YEAST ;  O60155, YHY6_SCHPO ;
//
ID   6.1.1.16
DE   Cysteine--tRNA ligase.
AN   Cysteine translase.
AN   Cysteinyl-tRNA synthetase.
CA   ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).
PR   PROSITE; PDOC00161;
DR   Q39A07, SYC1_BURS3 ;  Q6LT67, SYC1_PHOPR ;  Q83HS8, SYC1_TROW8 ;
DR   Q83GF1, SYC1_TROWT ;  Q39EY8, SYC2_BURS3 ;  Q6LHY2, SYC2_PHOPR ;
DR   Q83HQ8, SYC2_TROW8 ;  Q83GH3, SYC2_TROWT ;  Q5F408, SYCC_CHICK ;
DR   Q54KR1, SYCC_DICDI ;  Q7KN90, SYCC_DROME ;  Q291L4, SYCC_DROPS ;
DR   P49589, SYCC_HUMAN ;  Q4R550, SYCC_MACFA ;  Q9ER72, SYCC_MOUSE ;
DR   Q7ZWR2, SYCC_XENLA ;  Q5M7N8, SYCC_XENTR ;  Q2KIF8, SYCM_BOVIN ;
DR   Q54ZY3, SYCM_DICDI ;  Q9HA77, SYCM_HUMAN ;  Q8BYM8, SYCM_MOUSE ;
DR   Q6PA41, SYCM_XENLA ;  Q6DJ95, SYCM_XENTR ;  A9NEI9, SYC_ACHLI  ;
DR   A1TPK8, SYC_ACIAC  ;  Q6FC71, SYC_ACIAD  ;  B7GWA1, SYC_ACIB3  ;
DR   B7IBU3, SYC_ACIB5  ;  B2HX34, SYC_ACIBC  ;  Q1IJF8, SYC_ACIBL  ;
DR   B0VS71, SYC_ACIBS  ;  A3M419, SYC_ACIBT  ;  B0VAU1, SYC_ACIBY  ;
DR   A0LQZ8, SYC_ACIC1  ;  A5FYD2, SYC_ACICJ  ;  B9MAU5, SYC_ACIET  ;
DR   A1W6E1, SYC_ACISJ  ;  A3N0S3, SYC_ACTP2  ;  B3GXR0, SYC_ACTP7  ;
DR   B0BPJ8, SYC_ACTPJ  ;  A6VQ79, SYC_ACTSZ  ;  Q9YBK6, SYC_AERPE  ;
DR   B9JCA5, SYC_AGRRK  ;  Q8UGG4, SYC_AGRT5  ;  Q0VML5, SYC_ALCBS  ;
DR   Q0A7N3, SYC_ALHEH  ;  B6EH43, SYC_ALISL  ;  A6TWK5, SYC_ALKMQ  ;
DR   A8MLB7, SYC_ALKOO  ;  B8JDH1, SYC_ANAD2  ;  Q2IQG7, SYC_ANADE  ;
DR   A7HDA1, SYC_ANADF  ;  Q5PB14, SYC_ANAMM  ;  Q2GKF4, SYC_ANAPZ  ;
DR   B4UGC3, SYC_ANASK  ;  B9MMM6, SYC_ANATD  ;  Q3M6R3, SYC_ANAVT  ;
DR   B7GJ46, SYC_ANOFW  ;  O67163, SYC_AQUAE  ;  A8ERE6, SYC_ARCB4  ;
DR   O29836, SYC_ARCFU  ;  Q5P1H8, SYC_AROAE  ;  A1R383, SYC_ARTAT  ;
DR   B8HCR7, SYC_ARTCA  ;  A0JSV8, SYC_ARTS2  ;  Q2NIP7, SYC_AYWBP  ;
DR   O07045, SYC_AZOBR  ;  A8I4X6, SYC_AZOC5  ;  B6YQU1, SYC_AZOPC  ;
DR   C1DHE6, SYC_AZOVD  ;  A7Z0L6, SYC_BACA2  ;  C3P9N5, SYC_BACAA  ;
DR   C3LJ62, SYC_BACAC  ;  A0R8G1, SYC_BACAH  ;  Q81VV1, SYC_BACAN  ;
DR   B7JK97, SYC_BACC0  ;  Q73FB7, SYC_BACC1  ;  B7ISZ9, SYC_BACC2  ;
DR   C1ET19, SYC_BACC3  ;  B7HJ28, SYC_BACC4  ;  B7HQS4, SYC_BACC7  ;
DR   A7GK01, SYC_BACCN  ;  B9IZH4, SYC_BACCQ  ;  Q81J59, SYC_BACCR  ;
DR   Q63HB0, SYC_BACCZ  ;  Q5LIT7, SYC_BACFN  ;  Q64ZY1, SYC_BACFR  ;
DR   Q9KGF4, SYC_BACHD  ;  Q6HPS8, SYC_BACHK  ;  Q65PC8, SYC_BACLD  ;
DR   A8F962, SYC_BACP2  ;  Q5WLT3, SYC_BACSK  ;  Q06752, SYC_BACSU  ;
DR   Q8A2F4, SYC_BACTN  ;  A6KZ38, SYC_BACV8  ;  A9VNA2, SYC_BACWK  ;
DR   A1US43, SYC_BARBK  ;  Q6G5G9, SYC_BARHE  ;  Q6G073, SYC_BARQU  ;
DR   A9IRQ9, SYC_BART1  ;  Q1LTX2, SYC_BAUCH  ;  Q6MKR7, SYC_BDEBA  ;
DR   B2IEE1, SYC_BEII9  ;  C5BYT3, SYC_BEUC1  ;  Q8G7G5, SYC_BIFLO  ;
DR   Q7VRB4, SYC_BLOFL  ;  Q493A1, SYC_BLOPB  ;  Q2KX38, SYC_BORA1  ;
DR   Q0SMQ8, SYC_BORAP  ;  Q7WLL0, SYC_BORBR  ;  O51545, SYC_BORBU  ;
DR   B7J2G1, SYC_BORBZ  ;  Q660S3, SYC_BORGA  ;  B2S0U7, SYC_BORHD  ;
DR   Q7W862, SYC_BORPA  ;  Q7VX96, SYC_BORPE  ;  A1R030, SYC_BORT9  ;
DR   C0R1J9, SYC_BRAHW  ;  Q89NP8, SYC_BRAJA  ;  A5EHE7, SYC_BRASB  ;
DR   C0ZIF7, SYC_BREBN  ;  B2S4T7, SYC_BRUA1  ;  Q2YN22, SYC_BRUA2  ;
DR   Q57E65, SYC_BRUAB  ;  A9MA50, SYC_BRUC2  ;  C0RI19, SYC_BRUMB  ;
DR   Q8YG89, SYC_BRUME  ;  A5VPL3, SYC_BRUO2  ;  B0CL02, SYC_BRUSI  ;
DR   Q8G1N5, SYC_BRUSU  ;  B8D9R3, SYC_BUCA5  ;  P57558, SYC_BUCAI  ;
DR   P46241, SYC_BUCAP  ;  B8D815, SYC_BUCAT  ;  P59421, SYC_BUCBP  ;
DR   Q057D6, SYC_BUCCC  ;  B1YSM8, SYC_BURA4  ;  Q1BHP1, SYC_BURCA  ;
DR   B1JUK8, SYC_BURCC  ;  A0K8K2, SYC_BURCH  ;  B4ED73, SYC_BURCJ  ;
DR   Q0BDV4, SYC_BURCM  ;  A9AHN6, SYC_BURM1  ;  A3ML43, SYC_BURM7  ;
DR   A2SAX8, SYC_BURM9  ;  Q62J37, SYC_BURMA  ;  A1V5G8, SYC_BURMS  ;
DR   A3NWX8, SYC_BURP0  ;  Q3JQT6, SYC_BURP1  ;  A3NB50, SYC_BURP6  ;
DR   Q63SS8, SYC_BURPS  ;  Q2SX78, SYC_BURTA  ;  A4JFD0, SYC_BURVG  ;
DR   Q13X60, SYC_BURXL  ;  A4XHE2, SYC_CALS8  ;  A7ZDQ1, SYC_CAMC1  ;
DR   A7GYB4, SYC_CAMC5  ;  A0RP30, SYC_CAMFF  ;  A7I0X6, SYC_CAMHC  ;
DR   A8FLL5, SYC_CAMJ8  ;  A7H447, SYC_CAMJD  ;  Q9PPB8, SYC_CAMJE  ;
DR   A1VZF0, SYC_CAMJJ  ;  Q5HUZ0, SYC_CAMJR  ;  B9KFX4, SYC_CAMLR  ;
DR   Q3A9P1, SYC_CARHZ  ;  B8GZS3, SYC_CAUCN  ;  Q9AAY2, SYC_CAUCR  ;
DR   B0T101, SYC_CAUSK  ;  Q5L546, SYC_CHLAB  ;  Q3APK6, SYC_CHLCH  ;
DR   Q821U7, SYC_CHLCV  ;  Q255U1, SYC_CHLFF  ;  Q9PLE0, SYC_CHLMU  ;
DR   Q9Z6X4, SYC_CHLPN  ;  Q3KKR0, SYC_CHLTA  ;  Q8KAK2, SYC_CHLTE  ;
DR   O84787, SYC_CHLTR  ;  Q1QVV6, SYC_CHRSD  ;  Q7NX82, SYC_CHRVO  ;
DR   A5CTY3, SYC_CLAM3  ;  B0RAX1, SYC_CLAMS  ;  Q97ED6, SYC_CLOAB  ;
DR   A7FZ91, SYC_CLOB1  ;  C3KVS3, SYC_CLOB6  ;  A6LPP1, SYC_CLOB8  ;
DR   B2UY90, SYC_CLOBA  ;  B2TIF6, SYC_CLOBB  ;  A5I7M8, SYC_CLOBH  ;
DR   C1FMX3, SYC_CLOBJ  ;  B1IGH6, SYC_CLOBK  ;  A7GJ96, SYC_CLOBL  ;
DR   B1KTA5, SYC_CLOBM  ;  Q18CD5, SYC_CLOD6  ;  B9DY88, SYC_CLOK1  ;
DR   A5N4M6, SYC_CLOK5  ;  A0PXS5, SYC_CLONN  ;  Q0TMM4, SYC_CLOP1  ;
DR   Q8XHQ5, SYC_CLOPE  ;  A9KSM5, SYC_CLOPH  ;  Q0SQC1, SYC_CLOPS  ;
DR   Q890M4, SYC_CLOTE  ;  A3DH43, SYC_CLOTH  ;  Q47XL5, SYC_COLP3  ;
DR   Q6NFC3, SYC_CORDI  ;  Q8FMI8, SYC_COREF  ;  A4QH41, SYC_CORGB  ;
DR   Q8NMD7, SYC_CORGL  ;  Q4JXJ2, SYC_CORJK  ;  C4LH17, SYC_CORK4  ;
DR   A9KBJ2, SYC_COXBN  ;  A9N924, SYC_COXBR  ;  Q83BL7, SYC_COXBU  ;
DR   Q0KCA9, SYC_CUPNH  ;  Q473D3, SYC_CUPPJ  ;  B3R4D1, SYC_CUPTR  ;
DR   B8HQA4, SYC_CYAP4  ;  B7K7T8, SYC_CYAP7  ;  B7JUH4, SYC_CYAP8  ;
DR   Q11PK9, SYC_CYTH3  ;  Q47HK6, SYC_DECAR  ;  Q3ZAD5, SYC_DEHE1  ;
DR   A5FP90, SYC_DEHSB  ;  Q3ZWG4, SYC_DEHSC  ;  Q1IXM5, SYC_DEIGD  ;
DR   Q9RTT6, SYC_DEIRA  ;  A9BZ45, SYC_DELAS  ;  C6BS23, SYC_DESAD  ;
DR   B1I0T1, SYC_DESAP  ;  B8J0S2, SYC_DESDA  ;  Q30ZH8, SYC_DESDG  ;
DR   B8G1U2, SYC_DESHD  ;  Q250Q6, SYC_DESHY  ;  C4XSW5, SYC_DESMR  ;
DR   Q6AJ23, SYC_DESPS  ;  A4J0Y9, SYC_DESRM  ;  Q72BQ5, SYC_DESVH  ;
DR   B8DKL0, SYC_DESVM  ;  A1VDQ5, SYC_DESVV  ;  A5EWG6, SYC_DICNV  ;
DR   B5YAD0, SYC_DICT6  ;  B8E391, SYC_DICTD  ;  A8LLR2, SYC_DINSH  ;
DR   A7ZIT5, SYC_ECO24  ;  B7UKK3, SYC_ECO27  ;  B7ME49, SYC_ECO45  ;
DR   B7L7F3, SYC_ECO55  ;  Q8XCT9, SYC_ECO57  ;  B5YPP1, SYC_ECO5E  ;
DR   B7NL20, SYC_ECO7I  ;  B7MRI9, SYC_ECO81  ;  B7M4M9, SYC_ECO8A  ;
DR   C4ZUX4, SYC_ECOBW  ;  B1XGC4, SYC_ECODH  ;  A7ZXI1, SYC_ECOHS  ;
DR   A1A8J2, SYC_ECOK1  ;  Q0TKB5, SYC_ECOL5  ;  Q8FK44, SYC_ECOL6  ;
DR   B1IZ75, SYC_ECOLC  ;  P21888, SYC_ECOLI  ;  B7N980, SYC_ECOLU  ;
DR   B6I0H1, SYC_ECOSE  ;  B1LKE5, SYC_ECOSM  ;  Q1RF08, SYC_ECOUT  ;
DR   C5B8V6, SYC_EDWI9  ;  Q3YSF3, SYC_EHRCJ  ;  Q2GG67, SYC_EHRCR  ;
DR   Q5FHI9, SYC_EHRRG  ;  Q5HBK5, SYC_EHRRW  ;  Q8SRE0, SYC_ENCCU  ;
DR   A4W7I4, SYC_ENT38  ;  Q839V5, SYC_ENTFA  ;  A7MK00, SYC_ENTS8  ;
DR   Q6D2E4, SYC_ERWCT  ;  B2VBD5, SYC_ERWT9  ;  B7LJI4, SYC_ESCF3  ;
DR   C4Z3N5, SYC_EUBE2  ;  B1YGS9, SYC_EXIS2  ;  C4KZR7, SYC_EXISA  ;
DR   A7HKV1, SYC_FERNB  ;  B0S0W3, SYC_FINM2  ;  A5FHM5, SYC_FLAJ1  ;
DR   A6GX80, SYC_FLAPJ  ;  B0U0I3, SYC_FRAP2  ;  Q2J545, SYC_FRASC  ;
DR   Q14G14, SYC_FRAT1  ;  A7NE53, SYC_FRATF  ;  Q2A1T7, SYC_FRATH  ;
DR   B2SFH9, SYC_FRATM  ;  A0Q4Q1, SYC_FRATN  ;  Q0BKI3, SYC_FRATO  ;
DR   Q5NEL1, SYC_FRATT  ;  A4IWF2, SYC_FRATW  ;  Q8RIK9, SYC_FUSNN  ;
DR   B5EEK6, SYC_GEOBB  ;  Q5L429, SYC_GEOKA  ;  B3E1P0, SYC_GEOLS  ;
DR   Q39ZL8, SYC_GEOMG  ;  B9LZV4, SYC_GEOSF  ;  Q747A2, SYC_GEOSL  ;
DR   C6E7P0, SYC_GEOSM  ;  C5D3P6, SYC_GEOSW  ;  A4IJG8, SYC_GEOTN  ;
DR   A5G949, SYC_GEOUR  ;  Q7NMB5, SYC_GLOVI  ;  Q5FQ31, SYC_GLUOX  ;
DR   Q0BT18, SYC_GRABC  ;  A0M500, SYC_GRAFK  ;  Q7VMA0, SYC_HAEDU  ;
DR   Q4QPG7, SYC_HAEI8  ;  A5UFP3, SYC_HAEIG  ;  P43816, SYC_HAEIN  ;
DR   B8F392, SYC_HAEPS  ;  Q0I1Q1, SYC_HAES1  ;  B0UVH6, SYC_HAES2  ;
DR   Q2SK40, SYC_HAHCH  ;  A1WT89, SYC_HALHL  ;  Q5V2M3, SYC_HALMA  ;
DR   Q9HQL9, SYC_HALSA  ;  C4K6G8, SYC_HAMD5  ;  Q17WH3, SYC_HELAH  ;
DR   Q7VIT7, SYC_HELHP  ;  B0TC35, SYC_HELMI  ;  B6JMA7, SYC_HELP2  ;
DR   B5Z7P5, SYC_HELPG  ;  Q1CSY9, SYC_HELPH  ;  Q9ZKW6, SYC_HELPJ  ;
DR   B2UU37, SYC_HELPS  ;  P41259, SYC_HELPY  ;  A4G4M2, SYC_HERAR  ;
DR   B4U9I4, SYC_HYDS0  ;  Q0BXB7, SYC_HYPNA  ;  Q5QYP3, SYC_IDILO  ;
DR   A8AB68, SYC_IGNH4  ;  A6SZV1, SYC_JANMA  ;  Q28QY7, SYC_JANSC  ;
DR   A6W6G0, SYC_KINRD  ;  B5Y0K6, SYC_KLEP3  ;  A6T5R2, SYC_KLEP7  ;
DR   B2GFS8, SYC_KOCRD  ;  Q5FM34, SYC_LACAC  ;  Q03SU6, SYC_LACBA  ;
DR   Q035S0, SYC_LACC3  ;  B3WA35, SYC_LACCB  ;  Q1G8Z0, SYC_LACDA  ;
DR   Q048S9, SYC_LACDB  ;  B2GAB5, SYC_LACF3  ;  Q045X8, SYC_LACGA  ;
DR   A8YTD3, SYC_LACH4  ;  Q74L26, SYC_LACJO  ;  Q9CEJ0, SYC_LACLA  ;
DR   A2RMS1, SYC_LACLM  ;  Q02WZ9, SYC_LACLS  ;  Q88YX9, SYC_LACPL  ;
DR   A5VI99, SYC_LACRD  ;  B2G5S5, SYC_LACRJ  ;  Q1WSS5, SYC_LACS1  ;
DR   Q38UZ6, SYC_LACSS  ;  C1D7F5, SYC_LARHH  ;  Q1MQR5, SYC_LAWIP  ;
DR   Q5X5P9, SYC_LEGPA  ;  A5IBG0, SYC_LEGPC  ;  Q5ZVY1, SYC_LEGPH  ;
DR   Q5WX29, SYC_LEGPL  ;  Q6ADI1, SYC_LEIXX  ;  Q04SB0, SYC_LEPBJ  ;
DR   Q050D6, SYC_LEPBL  ;  Q72QT1, SYC_LEPIC  ;  Q8F525, SYC_LEPIN  ;
DR   B1MW68, SYC_LEUCK  ;  Q03ZR0, SYC_LEUMM  ;  Q92F36, SYC_LISIN  ;
DR   C1KYH2, SYC_LISMC  ;  Q724H3, SYC_LISMF  ;  B8DF15, SYC_LISMH  ;
DR   Q8YAB1, SYC_LISMO  ;  A0AF38, SYC_LISW6  ;  B1HNM3, SYC_LYSSC  ;
DR   Q2W7Y5, SYC_MAGSA  ;  A0L4P8, SYC_MAGSM  ;  Q65UY1, SYC_MANSM  ;
DR   A1U1Q7, SYC_MARAV  ;  Q0AM03, SYC_MARMM  ;  A6VX53, SYC_MARMS  ;
DR   Q6F230, SYC_MESFL  ;  Q11JR3, SYC_MESSB  ;  A6UWT0, SYC_META3  ;
DR   Q8TSP6, SYC_METAC  ;  Q46BZ5, SYC_METBF  ;  Q60BG8, SYC_METCA  ;
DR   Q1H417, SYC_METFK  ;  A9AAN8, SYC_METM6  ;  A6VG07, SYC_METM7  ;
DR   Q8PVQ1, SYC_METMA  ;  Q6LYD1, SYC_METMP  ;  A2SIM2, SYC_METPP  ;
DR   A4YIG5, SYC_METS5  ;  B8EMY2, SYC_METSB  ;  A6UP68, SYC_METVS  ;
DR   B0JJL5, SYC_MICAN  ;  C5C8X5, SYC_MICLC  ;  Q5UP36, SYC_MIMIV  ;
DR   Q2RFM3, SYC_MOOTA  ;  A0QAB5, SYC_MYCA1  ;  P0A635, SYC_MYCBO  ;
DR   A1KPR6, SYC_MYCBP  ;  C1AI39, SYC_MYCBT  ;  Q2ST11, SYC_MYCCT  ;
DR   Q7NAH7, SYC_MYCGA  ;  P47495, SYC_MYCGE  ;  A4T5K9, SYC_MYCGI  ;
DR   Q5ZZP6, SYC_MYCH2  ;  Q4A786, SYC_MYCH7  ;  Q4A947, SYC_MYCHJ  ;
DR   B8ZUA9, SYC_MYCLB  ;  P57990, SYC_MYCLE  ;  B2HJ21, SYC_MYCMM  ;
DR   Q6KIE2, SYC_MYCMO  ;  Q6MS23, SYC_MYCMS  ;  Q743W3, SYC_MYCPA  ;
DR   Q8EX28, SYC_MYCPE  ;  P75423, SYC_MYCPN  ;  Q98R33, SYC_MYCPU  ;
DR   A0R558, SYC_MYCS2  ;  A3Q6W0, SYC_MYCSJ  ;  A1UMF5, SYC_MYCSK  ;
DR   Q1B2P3, SYC_MYCSS  ;  A5U8Q5, SYC_MYCTA  ;  P0A634, SYC_MYCTU  ;
DR   A0PV27, SYC_MYCUA  ;  A1TG09, SYC_MYCVP  ;  Q74MI1, SYC_NANEQ  ;
DR   Q5F5D6, SYC_NEIG1  ;  Q9JWJ3, SYC_NEIMA  ;  Q9JXE6, SYC_NEIMB  ;
DR   Q2GE74, SYC_NEOSM  ;  Q0AJJ4, SYC_NITEC  ;  Q82Y45, SYC_NITEU  ;
DR   Q1QN87, SYC_NITHX  ;  Q2Y7U5, SYC_NITMU  ;  Q3J8Y9, SYC_NITOC  ;
DR   A6Q401, SYC_NITSB  ;  Q3STA1, SYC_NITWN  ;  Q5Z2R1, SYC_NOCFA  ;
DR   A1SNY3, SYC_NOCSJ  ;  Q8YXW5, SYC_NOSS1  ;  Q2G5Q6, SYC_NOVAD  ;
DR   Q8ETZ9, SYC_OCEIH  ;  A6X270, SYC_OCHA4  ;  Q04DQ8, SYC_OENOB  ;
DR   B6JHT8, SYC_OLICO  ;  Q6YR75, SYC_ONYPE  ;  B1ZSX8, SYC_OPITP  ;
DR   A5CFB8, SYC_ORITB  ;  B3CRX9, SYC_ORITI  ;  A6LFT6, SYC_PARD8  ;
DR   A1B9D5, SYC_PARDP  ;  A7HWJ0, SYC_PARL1  ;  Q6MBU0, SYC_PARUW  ;
DR   P57890, SYC_PASMU  ;  C6DAX2, SYC_PECCP  ;  Q03E41, SYC_PEDPA  ;
DR   Q3A8C9, SYC_PELCD  ;  Q3B6D2, SYC_PELLD  ;  A1AK01, SYC_PELPD  ;
DR   A5D5M0, SYC_PELTS  ;  Q4FLI7, SYC_PELUB  ;  C0QRE6, SYC_PERMH  ;
DR   A9BGT9, SYC_PETMO  ;  B4RE90, SYC_PHEZH  ;  Q7N0S5, SYC_PHOLL  ;
DR   A1VRB4, SYC_POLNA  ;  B1XUY8, SYC_POLNS  ;  Q129L2, SYC_POLSJ  ;
DR   A4SX62, SYC_POLSQ  ;  Q7MTR6, SYC_PORGI  ;  Q6AAT0, SYC_PROAC  ;
DR   A3PDX8, SYC_PROM0  ;  A2C3T6, SYC_PROM1  ;  A8G5S9, SYC_PROM2  ;
DR   A2C808, SYC_PROM3  ;  A2BXK1, SYC_PROM5  ;  Q319Z9, SYC_PROM9  ;
DR   Q7VB63, SYC_PROMA  ;  B4F1M6, SYC_PROMH  ;  Q7V6K0, SYC_PROMM  ;
DR   Q7V0W1, SYC_PROMP  ;  A2BS39, SYC_PROMS  ;  Q46JT8, SYC_PROMT  ;
DR   Q48L06, SYC_PSE14  ;  A6V727, SYC_PSEA7  ;  B7VB84, SYC_PSEA8  ;
DR   Q02KT6, SYC_PSEAB  ;  Q9I2U7, SYC_PSEAE  ;  Q1IBP9, SYC_PSEE4  ;
DR   Q4K9S1, SYC_PSEF5  ;  C3JYD3, SYC_PSEFS  ;  Q3IF51, SYC_PSEHT  ;
DR   A4XVG1, SYC_PSEMY  ;  A5W458, SYC_PSEP1  ;  Q3KA28, SYC_PSEPF  ;
DR   B0KUU0, SYC_PSEPG  ;  Q88IU4, SYC_PSEPK  ;  B1J805, SYC_PSEPW  ;
DR   Q87YQ2, SYC_PSESM  ;  Q4ZVN9, SYC_PSEU2  ;  A4VL73, SYC_PSEU5  ;
DR   Q4FRZ9, SYC_PSYA2  ;  Q1QC19, SYC_PSYCK  ;  A5WEW9, SYC_PSYWF  ;
DR   Q9UYV2, SYC_PYRAB  ;  Q8ZYD8, SYC_PYRAE  ;  A4WH15, SYC_PYRAR  ;
DR   A3MS54, SYC_PYRCJ  ;  Q8U227, SYC_PYRFU  ;  O58370, SYC_PYRHO  ;
DR   A1RTJ7, SYC_PYRIL  ;  Q5JD45, SYC_PYRKO  ;  B2U9P8, SYC_RALPJ  ;
DR   Q8Y077, SYC_RALSO  ;  A9WLY4, SYC_RENSM  ;  B3PUS4, SYC_RHIE6  ;
DR   Q2KAA8, SYC_RHIEC  ;  Q1MJ22, SYC_RHIL3  ;  Q984X8, SYC_RHILO  ;
DR   B5ZWB3, SYC_RHILW  ;  Q92R20, SYC_RHIME  ;  Q7US70, SYC_RHOBA  ;
DR   B6ISG4, SYC_RHOCS  ;  Q21YS0, SYC_RHOFD  ;  C1BAC4, SYC_RHOOB  ;
DR   Q2IUP0, SYC_RHOP2  ;  Q07Q42, SYC_RHOP5  ;  Q6N8A7, SYC_RHOPA  ;
DR   Q216P6, SYC_RHOPB  ;  Q139D9, SYC_RHOPS  ;  B3QCS4, SYC_RHOPT  ;
DR   Q2RWK2, SYC_RHORT  ;  A3PJH4, SYC_RHOS1  ;  Q3J2V7, SYC_RHOS4  ;
DR   A4WU98, SYC_RHOS5  ;  B9KRV8, SYC_RHOSK  ;  Q0S888, SYC_RHOSR  ;
DR   C3PMC1, SYC_RICAE  ;  A8GM31, SYC_RICAH  ;  A8GUK2, SYC_RICB8  ;
DR   Q1RH02, SYC_RICBR  ;  A8EXE9, SYC_RICCK  ;  Q92JF6, SYC_RICCN  ;
DR   Q4UND9, SYC_RICFE  ;  A8F0I8, SYC_RICM5  ;  Q9ZE62, SYC_RICPR  ;
DR   C4K199, SYC_RICPU  ;  B0BW37, SYC_RICRO  ;  A8GQP6, SYC_RICRS  ;
DR   Q68XV4, SYC_RICTY  ;  Q164A4, SYC_ROSDO  ;  Q1AU11, SYC_RUBXD  ;
DR   Q21JG6, SYC_SACD2  ;  A4F6W7, SYC_SACEN  ;  B5EYD7, SYC_SALA4  ;
DR   A9MLA7, SYC_SALAR  ;  Q57S29, SYC_SALCH  ;  B5FLP7, SYC_SALDC  ;
DR   B5QUV0, SYC_SALEP  ;  B5R6X0, SYC_SALG2  ;  B4TA89, SYC_SALHS  ;
DR   B4SXP2, SYC_SALNS  ;  Q5PCE2, SYC_SALPA  ;  A9MW31, SYC_SALPB  ;
DR   C0PVI8, SYC_SALPC  ;  B5BCZ8, SYC_SALPK  ;  Q2S3T5, SYC_SALRD  ;
DR   B4TN59, SYC_SALSV  ;  Q8Z8P6, SYC_SALTI  ;  Q8ZR68, SYC_SALTY  ;
DR   Q09860, SYC_SCHPO  ;  A8GAY0, SYC_SERP5  ;  A1S4X2, SYC_SHEAM  ;
DR   B8E5F2, SYC_SHEB2  ;  A3D302, SYC_SHEB5  ;  A6WLP8, SYC_SHEB8  ;
DR   A9KWH4, SYC_SHEB9  ;  Q12L98, SYC_SHEDO  ;  Q07ZX5, SYC_SHEFN  ;
DR   B0TLV2, SYC_SHEHH  ;  A3QFX9, SYC_SHELP  ;  Q8EG22, SYC_SHEON  ;
DR   A8H617, SYC_SHEPA  ;  A4Y5H9, SYC_SHEPC  ;  B8CRG0, SYC_SHEPW  ;
DR   A0KYM2, SYC_SHESA  ;  A8FTH6, SYC_SHESH  ;  Q0HH98, SYC_SHESM  ;
DR   Q0HTK4, SYC_SHESR  ;  A1RL92, SYC_SHESW  ;  B1KLU0, SYC_SHEWM  ;
DR   B2TTB3, SYC_SHIB3  ;  Q324Y3, SYC_SHIBS  ;  Q32JL0, SYC_SHIDS  ;
DR   Q0T776, SYC_SHIF8  ;  Q83M27, SYC_SHIFL  ;  Q3Z4P5, SYC_SHISS  ;
DR   Q5LRJ6, SYC_SILPO  ;  Q1GHI0, SYC_SILST  ;  A6U7D9, SYC_SINMW  ;
DR   Q2NV45, SYC_SODGM  ;  Q021Y7, SYC_SOLUE  ;  A7WYU7, SYC_STAA1  ;
DR   A6TZ06, SYC_STAA2  ;  Q2FJB0, SYC_STAA3  ;  Q2G2M6, SYC_STAA8  ;
DR   A5IQ83, SYC_STAA9  ;  Q2YSD1, SYC_STAAB  ;  Q5HIE5, SYC_STAAC  ;
DR   A6QEI2, SYC_STAAE  ;  Q932G0, SYC_STAAM  ;  Q99W73, SYC_STAAN  ;
DR   Q6GJD9, SYC_STAAR  ;  Q6GBV8, SYC_STAAS  ;  A8YZM7, SYC_STAAT  ;
DR   Q8NXY7, SYC_STAAW  ;  B9DKW3, SYC_STACT  ;  Q5HRM3, SYC_STAEQ  ;
DR   Q8CTU1, SYC_STAES  ;  Q4L3I9, SYC_STAHJ  ;  A3DLW5, SYC_STAMF  ;
DR   Q49V39, SYC_STAS1  ;  P77986, SYC_STAXY  ;  Q3K3G5, SYC_STRA1  ;
DR   Q8E7F2, SYC_STRA3  ;  Q8E1Z4, SYC_STRA5  ;  Q82GD0, SYC_STRAW  ;
DR   Q9L0Q6, SYC_STRCO  ;  B4U570, SYC_STREM  ;  B1VS94, SYC_STRGG  ;
DR   Q8DWA9, SYC_STRMU  ;  Q99XZ9, SYC_STRP1  ;  P0DG32, SYC_STRP3  ;
DR   Q5X9W5, SYC_STRP6  ;  Q8NZD1, SYC_STRP8  ;  Q48RA7, SYC_STRPM  ;
DR   Q97S25, SYC_STRPN  ;  P0DG33, SYC_STRPQ  ;  Q8DQS8, SYC_STRR6  ;
DR   Q5M1W6, SYC_STRT1  ;  Q5M6F6, SYC_STRT2  ;  Q4JCA6, SYC_SULAC  ;
DR   Q30R91, SYC_SULDN  ;  A6Q8G9, SYC_SULNB  ;  Q97WE6, SYC_SULSO  ;
DR   B2V6B4, SYC_SULSY  ;  Q96YC3, SYC_SULTO  ;  Q67JP9, SYC_SYMTH  ;
DR   Q31MM7, SYC_SYNE7  ;  A0LIR9, SYC_SYNFM  ;  Q2JTF4, SYC_SYNJA  ;
DR   Q2JKL2, SYC_SYNJB  ;  B1XND1, SYC_SYNP2  ;  Q5MZA4, SYC_SYNP6  ;
DR   A5GM79, SYC_SYNPW  ;  Q7U8C0, SYC_SYNPX  ;  Q3AZ17, SYC_SYNS9  ;
DR   Q3AI74, SYC_SYNSC  ;  P74330, SYC_SYNY3  ;  C5BI15, SYC_TERTT  ;
DR   B7IFB7, SYC_THEAB  ;  Q9HJ27, SYC_THEAC  ;  Q8DHW6, SYC_THEEB  ;
DR   Q47TG4, SYC_THEFY  ;  C5A739, SYC_THEGJ  ;  A8F596, SYC_THELT  ;
DR   A6LJ41, SYC_THEM4  ;  Q9WZH8, SYC_THEMA  ;  B9KAQ8, SYC_THENN  ;
DR   B1YA45, SYC_THENV  ;  B6YUQ3, SYC_THEON  ;  A5IJ66, SYC_THEP1  ;
DR   B0KCH9, SYC_THEP3  ;  A1RYM3, SYC_THEPD  ;  B0K5F6, SYC_THEPX  ;
DR   B1L7Y7, SYC_THESQ  ;  Q72KB0, SYC_THET2  ;  Q5SJV9, SYC_THET8  ;
DR   Q8R7T3, SYC_THETN  ;  Q978Z5, SYC_THEVO  ;  B5YID4, SYC_THEYD  ;
DR   Q31H54, SYC_THICR  ;  Q3SHN1, SYC_THIDA  ;  B8GNT5, SYC_THISH  ;
DR   C4LG04, SYC_TOLAT  ;  Q73RJ6, SYC_TREDE  ;  O83129, SYC_TREPA  ;
DR   B2S239, SYC_TREPS  ;  Q10XJ9, SYC_TRIEI  ;  B1GYT2, SYC_UNCTG  ;
DR   Q9PR21, SYC_UREPA  ;  C5CPX0, SYC_VARPS  ;  A1WSL6, SYC_VEREI  ;
DR   A5F763, SYC_VIBC3  ;  Q9KQZ9, SYC_VIBCH  ;  C3LNF1, SYC_VIBCM  ;
DR   Q5E4F1, SYC_VIBF1  ;  Q87QJ9, SYC_VIBPA  ;  B7VGZ1, SYC_VIBSL  ;
DR   Q8D8R1, SYC_VIBVU  ;  Q7MLR5, SYC_VIBVY  ;  Q8D2V9, SYC_WIGBR  ;
DR   Q73IL1, SYC_WOLPM  ;  B3CN54, SYC_WOLPP  ;  Q7MA68, SYC_WOLSU  ;
DR   Q5GRV6, SYC_WOLTR  ;  C0R5B6, SYC_WOLWR  ;  Q8PK23, SYC_XANAC  ;
DR   Q3BSH9, SYC_XANC5  ;  Q4UVJ3, SYC_XANC8  ;  Q8P8J0, SYC_XANCP  ;
DR   Q2P2E8, SYC_XANOM  ;  Q5GZD9, SYC_XANOR  ;  A7IPJ0, SYC_XANP2  ;
DR   Q9PEN3, SYC_XYLFA  ;  Q87EL7, SYC_XYLFT  ;  P53852, SYC_YEAST  ;
DR   A1JNP9, SYC_YERE8  ;  A7FL46, SYC_YERP3  ;  Q1C4U1, SYC_YERPA  ;
DR   B2K7N2, SYC_YERPB  ;  Q8ZCC0, SYC_YERPE  ;  A9R253, SYC_YERPG  ;
DR   Q1CKY1, SYC_YERPN  ;  A4TP63, SYC_YERPP  ;  Q66DK9, SYC_YERPS  ;
DR   B1JHJ1, SYC_YERPY  ;  Q5NR44, SYC_ZYMMO  ;
//
ID   6.1.1.17
DE   Glutamate--tRNA ligase.
AN   Glutamic acid translase.
AN   Glutamyl-tRNA synthetase.
CA   ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).
PR   PROSITE; PDOC00161;
DR   Q1IVP4, SYE1_ACIBL ;  A5FZX8, SYE1_ACICJ ;  B5EMF9, SYE1_ACIF5 ;
DR   Q0A936, SYE1_ALHEH ;  Q5PBW1, SYE1_ANAMM ;  Q2GLP6, SYE1_ANAPZ ;
DR   A8EQW9, SYE1_ARCB4 ;  A1USF5, SYE1_BARBK ;  Q6G3V8, SYE1_BARHE ;
DR   Q6FZP6, SYE1_BARQU ;  A9ISQ6, SYE1_BART1 ;  B2IKL1, SYE1_BEII9 ;
DR   B2S5M8, SYE1_BRUA1 ;  Q2YQ56, SYE1_BRUA2 ;  Q57DB3, SYE1_BRUAB ;
DR   A9MB31, SYE1_BRUC2 ;  Q8YHG4, SYE1_BRUME ;  A5VQF9, SYE1_BRUO2 ;
DR   B0CGG7, SYE1_BRUSI ;  Q8G0S1, SYE1_BRUSU ;  A4XHE0, SYE1_CALS8 ;
DR   A7ZCB6, SYE1_CAMC1 ;  A7GXI1, SYE1_CAMC5 ;  A0RM82, SYE1_CAMFF ;
DR   A7HZN3, SYE1_CAMHC ;  A8FLQ4, SYE1_CAMJ8 ;  A7H295, SYE1_CAMJD ;
DR   Q9PP78, SYE1_CAMJE ;  A1VZI8, SYE1_CAMJJ ;  Q5HUV1, SYE1_CAMJR ;
DR   B6J5A0, SYE1_COXB1 ;  B6IZ09, SYE1_COXB2 ;  A9KBJ3, SYE1_COXBN ;
DR   A9NAJ6, SYE1_COXBR ;  Q83EV3, SYE1_COXBU ;  A8LMK2, SYE1_DINSH ;
DR   Q3YS31, SYE1_EHRCJ ;  Q2GHQ1, SYE1_EHRCR ;  Q5FGB6, SYE1_EHRRG ;
DR   Q5HAC1, SYE1_EHRRW ;  Q2NA91, SYE1_ERYLH ;  A7HKV0, SYE1_FERNB ;
DR   A9GZS1, SYE1_GLUDA ;  Q5FRG7, SYE1_GLUOX ;  Q0BTZ0, SYE1_GRABC ;
DR   A1WT90, SYE1_HALHL ;  Q17WZ1, SYE1_HELAH ;  Q7VHN8, SYE1_HELHP ;
DR   B6JL62, SYE1_HELP2 ;  B5Z6J9, SYE1_HELPG ;  Q1CU52, SYE1_HELPH ;
DR   Q9ZLZ7, SYE1_HELPJ ;  B2UST7, SYE1_HELPS ;  P96551, SYE1_HELPY ;
DR   Q0C1A6, SYE1_HYPNA ;  Q28RA3, SYE1_JANSC ;  Q03U68, SYE1_LACBA ;
DR   Q2W7Y6, SYE1_MAGSA ;  Q0AR08, SYE1_MARMM ;  Q11I44, SYE1_MESSB ;
DR   Q60BG7, SYE1_METCA ;  A9W910, SYE1_METEP ;  B1Z9T1, SYE1_METPB ;
DR   B1LUJ9, SYE1_METRJ ;  B0UQ09, SYE1_METS4 ;  Q2GDP4, SYE1_NEOSM ;
DR   Q3JEF2, SYE1_NITOC ;  A6Q354, SYE1_NITSB ;  Q2G9R1, SYE1_NOVAD ;
DR   A6X0K5, SYE1_OCHA4 ;  A5CD02, SYE1_ORITB ;  B3CRX8, SYE1_ORITI ;
DR   A1B0F1, SYE1_PARDP ;  A7HS42, SYE1_PARL1 ;  A9BJB2, SYE1_PETMO ;
DR   Q98MD0, SYE1_RHILO ;  B6ISG3, SYE1_RHOCS ;  Q2RWK3, SYE1_RHORT ;
DR   A3PHK2, SYE1_RHOS1 ;  Q9ZFA3, SYE1_RHOS4 ;  A4WPH4, SYE1_RHOS5 ;
DR   A8GN11, SYE1_RICAH ;  A8GWP2, SYE1_RICB8 ;  Q1RIM2, SYE1_RICBR ;
DR   A8EY39, SYE1_RICCK ;  Q92IH2, SYE1_RICCN ;  Q4UM43, SYE1_RICFE ;
DR   A8F197, SYE1_RICM5 ;  Q9ZDK3, SYE1_RICPR ;  B0BX35, SYE1_RICRO ;
DR   A8GRM9, SYE1_RICRS ;  Q68X46, SYE1_RICTY ;  Q16AX5, SYE1_ROSDO ;
DR   Q1AU10, SYE1_RUBXD ;  Q5LWB2, SYE1_SILPO ;  Q1GHK0, SYE1_SILST ;
DR   Q1GUX4, SYE1_SPHAL ;  A5V932, SYE1_SPHWW ;  Q30UA5, SYE1_SULDN ;
DR   A6Q6F9, SYE1_SULNB ;  Q2LQN4, SYE1_SYNAS ;  Q0AYF8, SYE1_SYNWW ;
DR   A8F597, SYE1_THELT ;  A6LJ42, SYE1_THEM4 ;  Q9X172, SYE1_THEMA ;
DR   A5IL67, SYE1_THEP1 ;  B0KCH7, SYE1_THEP3 ;  B0K5F4, SYE1_THEPX ;
DR   B1LAE7, SYE1_THESQ ;  Q8RB93, SYE1_THETN ;  Q73HV5, SYE1_WOLPM ;
DR   B3CNK5, SYE1_WOLPP ;  Q7M7L9, SYE1_WOLSU ;  Q5GSJ1, SYE1_WOLTR ;
DR   A7INJ6, SYE1_XANP2 ;  Q5NP36, SYE1_ZYMMO ;  Q1IVB1, SYE2_ACIBL ;
DR   A5G1Y4, SYE2_ACICJ ;  B5EL11, SYE2_ACIF5 ;  Q0A7N2, SYE2_ALHEH ;
DR   Q5PAG8, SYE2_ANAMM ;  Q2GKT8, SYE2_ANAPZ ;  A8EU50, SYE2_ARCB4 ;
DR   A1USG2, SYE2_BARBK ;  Q6G3V1, SYE2_BARHE ;  Q6FZN9, SYE2_BARQU ;
DR   A9ISS8, SYE2_BART1 ;  B2IGY0, SYE2_BEII9 ;  B2S5Z7, SYE2_BRUA1 ;
DR   Q2YRQ9, SYE2_BRUA2 ;  Q57CZ2, SYE2_BRUAB ;  A9M5G0, SYE2_BRUC2 ;
DR   Q8YH36, SYE2_BRUME ;  A5VQR9, SYE2_BRUO2 ;  B0CGU5, SYE2_BRUSI ;
DR   Q8G0E8, SYE2_BRUSU ;  A4XLI3, SYE2_CALS8 ;  A7ZFB9, SYE2_CAMC1 ;
DR   A7H0G1, SYE2_CAMC5 ;  A0RR62, SYE2_CAMFF ;  A7I338, SYE2_CAMHC ;
DR   A8FMZ3, SYE2_CAMJ8 ;  A7H3M3, SYE2_CAMJD ;  O52914, SYE2_CAMJE ;
DR   A1W0S2, SYE2_CAMJJ ;  Q5HTB9, SYE2_CAMJR ;  B6J4I8, SYE2_COXB1 ;
DR   B6J2J3, SYE2_COXB2 ;  A9KD63, SYE2_COXBN ;  A9N925, SYE2_COXBR ;
DR   Q83BL6, SYE2_COXBU ;  A8LIP0, SYE2_DINSH ;  Q3YR29, SYE2_EHRCJ ;
DR   Q2GGL8, SYE2_EHRCR ;  Q5FGW4, SYE2_EHRRG ;  Q5HB98, SYE2_EHRRW ;
DR   Q2N5Q3, SYE2_ERYLH ;  A7HL47, SYE2_FERNB ;  A9HLD9, SYE2_GLUDA ;
DR   Q5FQ35, SYE2_GLUOX ;  Q0BS88, SYE2_GRABC ;  A1WWI7, SYE2_HALHL ;
DR   Q17WW9, SYE2_HELAH ;  Q7VIM2, SYE2_HELHP ;  B6JLN1, SYE2_HELP2 ;
DR   B5Z716, SYE2_HELPG ;  Q1CTM7, SYE2_HELPH ;  B2UTI4, SYE2_HELPS ;
DR   Q0BZ24, SYE2_HYPNA ;  Q28L59, SYE2_JANSC ;  Q03SU7, SYE2_LACBA ;
DR   Q2W3G8, SYE2_MAGSA ;  Q0APU9, SYE2_MARMM ;  Q11HT5, SYE2_MESSB ;
DR   Q609J9, SYE2_METCA ;  A9W982, SYE2_METEP ;  B1ZAR5, SYE2_METPB ;
DR   B1M0I6, SYE2_METRJ ;  B0UL61, SYE2_METS4 ;  Q2GD33, SYE2_NEOSM ;
DR   Q3J8Y8, SYE2_NITOC ;  A6Q5I8, SYE2_NITSB ;  Q2G6Q3, SYE2_NOVAD ;
DR   A6X0R0, SYE2_OCHA4 ;  A5CFB7, SYE2_ORITB ;  B3CST4, SYE2_ORITI ;
DR   A1B8E0, SYE2_PARDP ;  A7HY03, SYE2_PARL1 ;  A9BGT8, SYE2_PETMO ;
DR   Q98LZ1, SYE2_RHILO ;  B6IST4, SYE2_RHOCS ;  Q2RTZ4, SYE2_RHORT ;
DR   A3PMJ1, SYE2_RHOS1 ;  Q3IZQ8, SYE2_RHOS4 ;  A4WX62, SYE2_RHOS5 ;
DR   A8GPB2, SYE2_RICAH ;  A8GX08, SYE2_RICB8 ;  Q1RJC6, SYE2_RICBR ;
DR   A8EZB8, SYE2_RICCK ;  Q92H06, SYE2_RICCN ;  Q4UME8, SYE2_RICFE ;
DR   A8F2B0, SYE2_RICM5 ;  Q9ZCT8, SYE2_RICPR ;  B0BUL7, SYE2_RICRO ;
DR   A8GT27, SYE2_RICRS ;  Q68WB4, SYE2_RICTY ;  Q163X3, SYE2_ROSDO ;
DR   Q1AS60, SYE2_RUBXD ;  Q5LRH2, SYE2_SILPO ;  Q1GEA9, SYE2_SILST ;
DR   Q1GNX2, SYE2_SPHAL ;  A5VB94, SYE2_SPHWW ;  Q30RP4, SYE2_SULDN ;
DR   A6Q9D4, SYE2_SULNB ;  Q2LUT2, SYE2_SYNAS ;  Q0AUF7, SYE2_SYNWW ;
DR   A8F791, SYE2_THELT ;  A6LM79, SYE2_THEM4 ;  Q9X2I8, SYE2_THEMA ;
DR   A5IMM2, SYE2_THEP1 ;  B0KAA6, SYE2_THEP3 ;  B0K403, SYE2_THEPX ;
DR   B1LBX4, SYE2_THESQ ;  Q8R7T1, SYE2_THETN ;  Q73H00, SYE2_WOLPM ;
DR   B3CLF5, SYE2_WOLPP ;  Q7MAG3, SYE2_WOLSU ;  Q5GSI3, SYE2_WOLTR ;
DR   A7IPJ5, SYE2_XANP2 ;  Q5NL22, SYE2_ZYMMO ;  Q54KB8, SYEC_DICDI ;
DR   Q8SSE4, SYEC_ENCCU ;  A9CSZ1, SYEC_ENTBH ;  C4VBI7, SYEC_NOSCE ;
DR   O13775, SYEC_SCHPO ;  P46655, SYEC_YEAST ;  Q5ZJ66, SYEM_CHICK ;
DR   Q0P499, SYEM_DANRE ;  Q5JPH6, SYEM_HUMAN ;  Q4R4F1, SYEM_MACFA ;
DR   Q9CXJ1, SYEM_MOUSE ;  Q9HDX9, SYEM_SCHPO ;  Q66JG3, SYEM_XENTR ;
DR   P48525, SYEM_YEAST ;  Q7SIA2, SYEP_CRIGR ;  P28668, SYEP_DROME ;
DR   P07814, SYEP_HUMAN ;  Q8CGC7, SYEP_MOUSE ;  B0C8D6, SYE_ACAM1  ;
DR   A9NEI5, SYE_ACHLI  ;  A1TNB1, SYE_ACIAC  ;  Q6F7C8, SYE_ACIAD  ;
DR   B2I0L0, SYE_ACIBC  ;  B0VPF6, SYE_ACIBS  ;  B0V8Q3, SYE_ACIBY  ;
DR   A0LSS7, SYE_ACIC1  ;  A1W9F0, SYE_ACISJ  ;  A3N1S5, SYE_ACTP2  ;
DR   B3H248, SYE_ACTP7  ;  B0BQK7, SYE_ACTPJ  ;  A6VLT3, SYE_ACTSZ  ;
DR   A0KNT0, SYE_AERHH  ;  Q9Y9H1, SYE_AERPE  ;  A4SJD4, SYE_AERS4  ;
DR   Q8U7H5, SYE_AGRT5  ;  B2UN91, SYE_AKKM8  ;  Q0VPE1, SYE_ALCBS  ;
DR   B6EJQ3, SYE_ALISL  ;  A6TWK7, SYE_ALKMQ  ;  A8MLB5, SYE_ALKOO  ;
DR   B3ERQ7, SYE_AMOA5  ;  Q2IL38, SYE_ANADE  ;  A7H9S6, SYE_ANADF  ;
DR   B4UI79, SYE_ANASK  ;  Q3M3H8, SYE_ANAVT  ;  O67271, SYE_AQUAE  ;
DR   Q9FEA2, SYE_ARATH  ;  O29979, SYE_ARCFU  ;  Q5NY25, SYE_AROAE  ;
DR   A1R7K6, SYE_ARTAT  ;  A0JXY5, SYE_ARTS2  ;  Q2NIP6, SYE_AYWBP  ;
DR   P45631, SYE_AZOBR  ;  A8I819, SYE_AZOC5  ;  B6YQF6, SYE_AZOPC  ;
DR   A1K5J1, SYE_AZOSB  ;  A7Z0L4, SYE_BACA2  ;  A0R8F9, SYE_BACAH  ;
DR   Q81VV3, SYE_BACAN  ;  Q73FB9, SYE_BACC1  ;  A7GJZ9, SYE_BACCN  ;
DR   Q81J61, SYE_BACCR  ;  Q63HB2, SYE_BACCZ  ;  Q5L883, SYE_BACFN  ;
DR   Q64NI3, SYE_BACFR  ;  Q9KGF6, SYE_BACHD  ;  Q6HPT0, SYE_BACHK  ;
DR   Q65PD0, SYE_BACLD  ;  A8F960, SYE_BACP2  ;  Q5WLT5, SYE_BACSK  ;
DR   P22250, SYE_BACSU  ;  Q8A455, SYE_BACTN  ;  A6L0E8, SYE_BACV8  ;
DR   A9VNA0, SYE_BACWK  ;  Q1LT18, SYE_BAUCH  ;  Q6MKR6, SYE_BDEBA  ;
DR   A0ZZS4, SYE_BIFAA  ;  B3DU87, SYE_BIFLD  ;  Q8G709, SYE_BIFLO  ;
DR   Q7VRU3, SYE_BLOFL  ;  Q492G6, SYE_BLOPB  ;  Q2KUY9, SYE_BORA1  ;
DR   Q0SNE1, SYE_BORAP  ;  Q7WFA9, SYE_BORBR  ;  O51345, SYE_BORBU  ;
DR   B5RLR1, SYE_BORDL  ;  Q661P7, SYE_BORGA  ;  B2S076, SYE_BORHD  ;
DR   Q7W3X9, SYE_BORPA  ;  A9I219, SYE_BORPD  ;  Q7VUU5, SYE_BORPE  ;
DR   B5RRI1, SYE_BORRA  ;  Q89KR5, SYE_BRAJA  ;  A5EK39, SYE_BRASB  ;
DR   A4YVF1, SYE_BRASO  ;  P57173, SYE_BUCAI  ;  Q8KA47, SYE_BUCAP  ;
DR   P59423, SYE_BUCBP  ;  Q058C8, SYE_BUCCC  ;  B1YSK3, SYE_BURA4  ;
DR   Q1BHL9, SYE_BURCA  ;  B1JUI6, SYE_BURCC  ;  A0K8I0, SYE_BURCH  ;
DR   B4ECR7, SYE_BURCJ  ;  Q0BDX9, SYE_BURCM  ;  A9AHQ3, SYE_BURM1  ;
DR   A3MKY8, SYE_BURM7  ;  A2SB31, SYE_BURM9  ;  Q62J82, SYE_BURMA  ;
DR   A1V5B3, SYE_BURMS  ;  A3NWS4, SYE_BURP0  ;  Q3JQY8, SYE_BURP1  ;
DR   A3NAZ3, SYE_BURP6  ;  B2JIQ8, SYE_BURP8  ;  B2SXN5, SYE_BURPP  ;
DR   Q63SX4, SYE_BURPS  ;  Q39F07, SYE_BURS3  ;  Q2SX36, SYE_BURTA  ;
DR   A4JFB2, SYE_BURVG  ;  Q13X76, SYE_BURXL  ;  A8M9D7, SYE_CALMQ  ;
DR   Q3A9N9, SYE_CARHZ  ;  Q9A721, SYE_CAUCR  ;  B0SZ02, SYE_CAUSK  ;
DR   B3PD15, SYE_CELJU  ;  A0RY20, SYE_CENSY  ;  A9WAX3, SYE_CHLAA  ;
DR   Q5L6T4, SYE_CHLAB  ;  Q3ATL0, SYE_CHLCH  ;  P59690, SYE_CHLCV  ;
DR   Q253E2, SYE_CHLFF  ;  B3EFG9, SYE_CHLL2  ;  Q9PJU7, SYE_CHLMU  ;
DR   P59691, SYE_CHLP6  ;  B3QQC6, SYE_CHLP8  ;  B3EMG1, SYE_CHLPB  ;
DR   A1BDK8, SYE_CHLPD  ;  Q9Z7Z3, SYE_CHLPN  ;  B0B818, SYE_CHLT2  ;
DR   B3QYR1, SYE_CHLT3  ;  Q3KLQ4, SYE_CHLTA  ;  B0BC83, SYE_CHLTB  ;
DR   Q9F724, SYE_CHLTE  ;  O84451, SYE_CHLTR  ;  Q1QY92, SYE_CHRSD  ;
DR   Q7NWP4, SYE_CHRVO  ;  A8ADJ2, SYE_CITK8  ;  A5CPZ8, SYE_CLAM3  ;
DR   B0RIP8, SYE_CLAMS  ;  Q97KC9, SYE_CLOAB  ;  A7FSY9, SYE_CLOB1  ;
DR   A6LTC5, SYE_CLOB8  ;  B2V5H4, SYE_CLOBA  ;  B2TND7, SYE_CLOBB  ;
DR   A5I0T6, SYE_CLOBH  ;  B1IIG7, SYE_CLOBK  ;  A7GCD9, SYE_CLOBL  ;
DR   B1KYV1, SYE_CLOBM  ;  Q18CD6, SYE_CLOD6  ;  A5N867, SYE_CLOK5  ;
DR   A0PZ93, SYE_CLONN  ;  Q0TRN9, SYE_CLOP1  ;  Q8XLP3, SYE_CLOPE  ;
DR   A9KRX7, SYE_CLOPH  ;  Q0SU18, SYE_CLOPS  ;  Q896M5, SYE_CLOTE  ;
DR   A3DD54, SYE_CLOTH  ;  Q47Z58, SYE_COLP3  ;  B5Y7R0, SYE_COPPD  ;
DR   Q6NHM1, SYE_CORDI  ;  Q8FPU9, SYE_COREF  ;  A4QDQ6, SYE_CORGB  ;
DR   Q8NQX9, SYE_CORGL  ;  Q4JUQ7, SYE_CORJK  ;  B1VG41, SYE_CORU7  ;
DR   Q0K926, SYE_CUPNH  ;  Q46ZE6, SYE_CUPPJ  ;  B3R1N9, SYE_CUPTR  ;
DR   B1WYU1, SYE_CYAA5  ;  Q11PQ4, SYE_CYTH3  ;  Q47GG0, SYE_DECAR  ;
DR   Q3Z6S3, SYE_DEHE1  ;  A5FPX2, SYE_DEHSB  ;  Q3ZYP4, SYE_DEHSC  ;
DR   Q1IY50, SYE_DEIGD  ;  Q9RX30, SYE_DEIRA  ;  A9BM51, SYE_DELAS  ;
DR   B1I4Z1, SYE_DESAP  ;  Q30Y02, SYE_DESDG  ;  Q250Q8, SYE_DESHY  ;
DR   A8ZWA3, SYE_DESOH  ;  Q6AJL4, SYE_DESPS  ;  A4J0Y7, SYE_DESRM  ;
DR   Q728Q1, SYE_DESVH  ;  A1VBA3, SYE_DESVV  ;  A5EV06, SYE_DICNV  ;
DR   B5YEP5, SYE_DICT6  ;  A7ZPK7, SYE_ECO24  ;  Q8XBN2, SYE_ECO57  ;
DR   B5YZV2, SYE_ECO5E  ;  B1X9R9, SYE_ECODH  ;  A8A2Q2, SYE_ECOHS  ;
DR   A1ADS2, SYE_ECOK1  ;  Q0TF64, SYE_ECOL5  ;  Q8FFC9, SYE_ECOL6  ;
DR   B1IX65, SYE_ECOLC  ;  P04805, SYE_ECOLI  ;  B6I6U7, SYE_ECOSE  ;
DR   B1LMJ5, SYE_ECOSM  ;  Q1R8W9, SYE_ECOUT  ;  B2KAV3, SYE_ELUMP  ;
DR   A4WD15, SYE_ENT38  ;  Q839V7, SYE_ENTFA  ;  A7MKV5, SYE_ENTS8  ;
DR   Q6D206, SYE_ERWCT  ;  B2VDY5, SYE_ERWT9  ;  B1YGS7, SYE_EXIS2  ;
DR   B0S0W2, SYE_FINM2  ;  A5FL73, SYE_FLAJ1  ;  A6H2H7, SYE_FLAPJ  ;
DR   Q0RF57, SYE_FRAAA  ;  B0U106, SYE_FRAP2  ;  Q2J816, SYE_FRASC  ;
DR   A8LCV4, SYE_FRASN  ;  Q14JD8, SYE_FRAT1  ;  A7N9Q8, SYE_FRATF  ;
DR   Q2A5I8, SYE_FRATH  ;  B2SE01, SYE_FRATM  ;  A0Q4G6, SYE_FRATN  ;
DR   Q0BNU3, SYE_FRATO  ;  Q5NHY6, SYE_FRATT  ;  A4IZU9, SYE_FRATW  ;
DR   Q8RDZ8, SYE_FUSNN  ;  B5EEE6, SYE_GEOBB  ;  Q5L431, SYE_GEOKA  ;
DR   B3E399, SYE_GEOLS  ;  Q39UV7, SYE_GEOMG  ;  P22249, SYE_GEOSE  ;
DR   Q74DU6, SYE_GEOSL  ;  A4IJG6, SYE_GEOTN  ;  A5G3W1, SYE_GEOUR  ;
DR   Q7NI06, SYE_GLOVI  ;  A0M6K0, SYE_GRAFK  ;  Q7VNZ3, SYE_HAEDU  ;
DR   Q4QNR5, SYE_HAEI8  ;  A5UAL5, SYE_HAEIE  ;  A5UG92, SYE_HAEIG  ;
DR   P43818, SYE_HAEIN  ;  Q0I297, SYE_HAES1  ;  B0USJ3, SYE_HAES2  ;
DR   Q2SK84, SYE_HAHCH  ;  Q5V5N9, SYE_HALMA  ;  B0R4Z6, SYE_HALS3  ;
DR   Q9HQI1, SYE_HALSA  ;  Q18GA5, SYE_HALWD  ;  B0TBU3, SYE_HELMI  ;
DR   A9AXJ1, SYE_HERA2  ;  A4G3S7, SYE_HERAR  ;  Q43768, SYE_HORVU  ;
DR   B4U896, SYE_HYDS0  ;  A2BK91, SYE_HYPBU  ;  Q5QX98, SYE_IDILO  ;
DR   A8ABI5, SYE_IGNH4  ;  A6SX06, SYE_JANMA  ;  A6W7Q5, SYE_KINRD  ;
DR   B5XVT8, SYE_KLEP3  ;  A6TC43, SYE_KLEP7  ;  B2GFK2, SYE_KOCRD  ;
DR   B1L5U2, SYE_KORCO  ;  Q5FM35, SYE_LACAC  ;  Q035R5, SYE_LACC3  ;
DR   B3WA39, SYE_LACCB  ;  Q1G8Y5, SYE_LACDA  ;  Q048S3, SYE_LACDB  ;
DR   O86083, SYE_LACDE  ;  B2GAB3, SYE_LACF3  ;  Q045X9, SYE_LACGA  ;
DR   A8YTD2, SYE_LACH4  ;  Q74L27, SYE_LACJO  ;  Q9CDZ7, SYE_LACLA  ;
DR   A2RNK5, SYE_LACLM  ;  Q02W76, SYE_LACLS  ;  Q88YY0, SYE_LACPL  ;
DR   A5VKT4, SYE_LACRD  ;  B2G868, SYE_LACRJ  ;  Q1WSS4, SYE_LACS1  ;
DR   Q38YY5, SYE_LACSS  ;  Q1MR60, SYE_LAWIP  ;  Q5X3Z5, SYE_LEGPA  ;
DR   A5ID69, SYE_LEGPC  ;  Q5ZU96, SYE_LEGPH  ;  Q5WVE0, SYE_LEGPL  ;
DR   Q6AEQ1, SYE_LEIXX  ;  B0SCM4, SYE_LEPBA  ;  Q04PF0, SYE_LEPBJ  ;
DR   Q055X5, SYE_LEPBL  ;  B0SKQ2, SYE_LEPBP  ;  B1XY56, SYE_LEPCP  ;
DR   Q72M46, SYE_LEPIC  ;  Q8EYM3, SYE_LEPIN  ;  B1MWU1, SYE_LEUCK  ;
DR   Q03ZR1, SYE_LEUMM  ;  Q92F38, SYE_LISIN  ;  Q724H5, SYE_LISMF  ;
DR   Q8YAB3, SYE_LISMO  ;  A0AF36, SYE_LISW6  ;  B1HNM5, SYE_LYSSC  ;
DR   A0L669, SYE_MAGSM  ;  Q65VB3, SYE_MANSM  ;  A1U1V3, SYE_MARAV  ;
DR   A6VZB3, SYE_MARMS  ;  Q6F0G6, SYE_MESFL  ;  A6UW15, SYE_META3  ;
DR   Q8TT52, SYE_METAC  ;  A7IAG1, SYE_METB6  ;  Q46CG5, SYE_METBF  ;
DR   Q12TN7, SYE_METBU  ;  Q1H0X9, SYE_METFK  ;  Q2FTH6, SYE_METHJ  ;
DR   B3DXK4, SYE_METI4  ;  Q58772, SYE_METJA  ;  Q8TXB7, SYE_METKA  ;
DR   A2SRG2, SYE_METLZ  ;  A4FXG8, SYE_METM5  ;  A9AAT7, SYE_METM6  ;
DR   A6VFU7, SYE_METM7  ;  Q8PW52, SYE_METMA  ;  A3CWJ3, SYE_METMJ  ;
DR   Q6LYI0, SYE_METMP  ;  A5UN79, SYE_METS3  ;  A4YIL8, SYE_METS5  ;
DR   Q2NFU2, SYE_METST  ;  O26157, SYE_METTH  ;  Q50543, SYE_METTM  ;
DR   A0B966, SYE_METTP  ;  A6UP25, SYE_METVS  ;  B0JY53, SYE_MICAN  ;
DR   Q2RJE3, SYE_MOOTA  ;  B3PN19, SYE_MYCA5  ;  B1MDQ5, SYE_MYCA9  ;
DR   A5IZ19, SYE_MYCAP  ;  P0A637, SYE_MYCBO  ;  A1KMY6, SYE_MYCBP  ;
DR   Q2SSZ1, SYE_MYCCT  ;  Q7NAE5, SYE_MYCGA  ;  P47700, SYE_MYCGE  ;
DR   A4TE16, SYE_MYCGI  ;  Q601G1, SYE_MYCH2  ;  Q4A8M4, SYE_MYCH7  ;
DR   Q4AAJ3, SYE_MYCHJ  ;  O33120, SYE_MYCLE  ;  B2HIH4, SYE_MYCMM  ;
DR   Q6KIT3, SYE_MYCMO  ;  Q6MUA6, SYE_MYCMS  ;  Q73VI4, SYE_MYCPA  ;
DR   Q8EU94, SYE_MYCPE  ;  P75114, SYE_MYCPN  ;  P53662, SYE_MYCPU  ;
DR   A0QUY7, SYE_MYCS2  ;  Q4A6V0, SYE_MYCS5  ;  A3PXR0, SYE_MYCSJ  ;
DR   A1UEA6, SYE_MYCSK  ;  Q1BAQ6, SYE_MYCSS  ;  A5U703, SYE_MYCTA  ;
DR   P0A636, SYE_MYCTU  ;  A0PPY8, SYE_MYCUA  ;  A1T6Z8, SYE_MYCVP  ;
DR   Q1D8Y1, SYE_MYXXD  ;  Q74MU5, SYE_NANEQ  ;  Q3IPL2, SYE_NATPD  ;
DR   B2A4B3, SYE_NATTJ  ;  Q5F5J8, SYE_NEIG1  ;  B4RPQ3, SYE_NEIG2  ;
DR   A9LZH6, SYE_NEIM0  ;  Q9JWT4, SYE_NEIMA  ;  Q9K1R6, SYE_NEIMB  ;
DR   A1KWM9, SYE_NEIMF  ;  Q0AIP6, SYE_NITEC  ;  Q82U77, SYE_NITEU  ;
DR   Q1QMM2, SYE_NITHX  ;  A9A423, SYE_NITMS  ;  Q2Y8L6, SYE_NITMU  ;
DR   Q3SRI7, SYE_NITWN  ;  Q5YRX6, SYE_NOCFA  ;  A1SM03, SYE_NOCSJ  ;
DR   B2IYI1, SYE_NOSP7  ;  Q8YS86, SYE_NOSS1  ;  Q8EU02, SYE_OCEIH  ;
DR   Q04GX5, SYE_OENOB  ;  B6JH82, SYE_OLICO  ;  Q6YR76, SYE_ONYPE  ;
DR   B1ZUV7, SYE_OPITP  ;  A6LEA1, SYE_PARD8  ;  Q6MEN1, SYE_PARUW  ;
DR   P57906, SYE_PASMU  ;  Q03E40, SYE_PEDPA  ;  Q3A413, SYE_PELCD  ;
DR   Q3B256, SYE_PELLD  ;  B4SCV6, SYE_PELPB  ;  A1AUQ6, SYE_PELPD  ;
DR   A5D5L8, SYE_PELTS  ;  Q4FM56, SYE_PELUB  ;  B4RBX8, SYE_PHEZH  ;
DR   Q7N6Y2, SYE_PHOLL  ;  Q6LTT8, SYE_PHOPR  ;  B1VA59, SYE_PHYAS  ;
DR   Q6L0N9, SYE_PICTO  ;  A1VL83, SYE_POLNA  ;  B1XUR6, SYE_POLNS  ;
DR   Q12D45, SYE_POLSJ  ;  A4SXF2, SYE_POLSQ  ;  B2RI67, SYE_PORG3  ;
DR   Q7MUF7, SYE_PORGI  ;  B4S404, SYE_PROA2  ;  Q6A6M1, SYE_PROAC  ;
DR   A3PBJ6, SYE_PROM0  ;  A2C0T1, SYE_PROM1  ;  A8G3I8, SYE_PROM2  ;
DR   A2C7H0, SYE_PROM3  ;  A9BE95, SYE_PROM4  ;  A2BVD5, SYE_PROM5  ;
DR   Q31C61, SYE_PROM9  ;  Q7VDB2, SYE_PROMA  ;  B4EZQ7, SYE_PROMH  ;
DR   Q7TUT7, SYE_PROMM  ;  Q7V2K3, SYE_PROMP  ;  A2BPV5, SYE_PROMS  ;
DR   Q46GU9, SYE_PROMT  ;  A4SGA5, SYE_PROVI  ;  Q48KA5, SYE_PSE14  ;
DR   Q15RR1, SYE_PSEA6  ;  A6V2T9, SYE_PSEA7  ;  Q02PU7, SYE_PSEAB  ;
DR   Q9XCL6, SYE_PSEAE  ;  Q1ICW8, SYE_PSEE4  ;  Q4KF16, SYE_PSEF5  ;
DR   Q3IHK6, SYE_PSEHT  ;  A4XVX2, SYE_PSEMY  ;  A5W6Z7, SYE_PSEP1  ;
DR   Q3KF35, SYE_PSEPF  ;  B0KF73, SYE_PSEPG  ;  Q88LF6, SYE_PSEPK  ;
DR   B1J522, SYE_PSEPW  ;  Q884C8, SYE_PSESM  ;  Q4ZV02, SYE_PSEU2  ;
DR   A4VNT7, SYE_PSEU5  ;  Q4FQ04, SYE_PSYA2  ;  Q1Q845, SYE_PSYCK  ;
DR   A1SVA7, SYE_PSYIN  ;  A5WBQ0, SYE_PSYWF  ;  Q9V1E3, SYE_PYRAB  ;
DR   Q8ZU33, SYE_PYRAE  ;  A4WKI4, SYE_PYRAR  ;  A3MV95, SYE_PYRCJ  ;
DR   Q8U064, SYE_PYRFU  ;  O59314, SYE_PYRHO  ;  A1RRG7, SYE_PYRIL  ;
DR   Q5JH16, SYE_PYRKO  ;  Q1LLF7, SYE_RALME  ;  B2U9R2, SYE_RALPJ  ;
DR   Q8Y065, SYE_RALSO  ;  A9WP26, SYE_RENSM  ;  B3Q0S3, SYE_RHIE6  ;
DR   Q2K425, SYE_RHIEC  ;  Q1MBL0, SYE_RHIL3  ;  B5ZQW4, SYE_RHILW  ;
DR   P15189, SYE_RHIME  ;  Q7UNF9, SYE_RHOBA  ;  Q21V06, SYE_RHOFD  ;
DR   Q2IW96, SYE_RHOP2  ;  Q07NH8, SYE_RHOP5  ;  Q6N5R5, SYE_RHOPA  ;
DR   Q215D4, SYE_RHOPB  ;  Q136B9, SYE_RHOPS  ;  B3Q6P5, SYE_RHOPT  ;
DR   Q0S2G8, SYE_RHOSR  ;  A7NLL2, SYE_ROSCS  ;  A5UTY2, SYE_ROSS1  ;
DR   A1AWC3, SYE_RUTMC  ;  Q21KM1, SYE_SACD2  ;  A4FMP6, SYE_SACEN  ;
DR   B5F0E6, SYE_SALA4  ;  A8LZ53, SYE_SALAI  ;  A9MIG3, SYE_SALAR  ;
DR   Q57LU0, SYE_SALCH  ;  B5FQB0, SYE_SALDC  ;  B5R3U6, SYE_SALEP  ;
DR   B5RCP1, SYE_SALG2  ;  B4TCE7, SYE_SALHS  ;  B4SZT6, SYE_SALNS  ;
DR   Q5PNE5, SYE_SALPA  ;  A9N372, SYE_SALPB  ;  B5BB76, SYE_SALPK  ;
DR   Q2S1L8, SYE_SALRD  ;  B4TQE9, SYE_SALSV  ;  P0A2K4, SYE_SALTI  ;
DR   A4XA62, SYE_SALTO  ;  P0A2K3, SYE_SALTY  ;  A8GHC5, SYE_SERP5  ;
DR   A1S7Q6, SYE_SHEAM  ;  A3D6C6, SYE_SHEB5  ;  A6WQ67, SYE_SHEB8  ;
DR   A9KUU5, SYE_SHEB9  ;  Q12L63, SYE_SHEDO  ;  Q07ZL0, SYE_SHEFN  ;
DR   B0TNB9, SYE_SHEHH  ;  A3QCW8, SYE_SHELP  ;  A8H2J4, SYE_SHEPA  ;
DR   A4Y8D7, SYE_SHEPC  ;  A0KV33, SYE_SHESA  ;  A8FXE0, SYE_SHESH  ;
DR   Q0HKH4, SYE_SHESM  ;  Q0HWS6, SYE_SHESR  ;  A1RI52, SYE_SHESW  ;
DR   B1KML5, SYE_SHEWM  ;  B2TX02, SYE_SHIB3  ;  Q31Y73, SYE_SHIBS  ;
DR   Q32DE6, SYE_SHIDS  ;  Q0T2A3, SYE_SHIF8  ;  Q83K84, SYE_SHIFL  ;
DR   Q3YZD6, SYE_SHISS  ;  A6UD99, SYE_SINMW  ;  Q2NSC4, SYE_SODGM  ;
DR   Q01WJ8, SYE_SOLUE  ;  A9GVA4, SYE_SORC5  ;  A7WYU4, SYE_STAA1  ;
DR   A6TZ04, SYE_STAA2  ;  Q2FJB2, SYE_STAA3  ;  Q2G241, SYE_STAA8  ;
DR   A5IQ81, SYE_STAA9  ;  Q2YSD3, SYE_STAAB  ;  Q5HIE7, SYE_STAAC  ;
DR   A6QEI0, SYE_STAAE  ;  P67021, SYE_STAAM  ;  P99170, SYE_STAAN  ;
DR   Q6GJE1, SYE_STAAR  ;  Q6GBW0, SYE_STAAS  ;  A8YZM5, SYE_STAAT  ;
DR   P67022, SYE_STAAW  ;  Q5HRM5, SYE_STAEQ  ;  Q8CTU3, SYE_STAES  ;
DR   Q4L3I7, SYE_STAHJ  ;  A3DMR5, SYE_STAMF  ;  Q49V37, SYE_STAS1  ;
DR   P77984, SYE_STAXY  ;  Q3K3R5, SYE_STRA1  ;  Q8E7P2, SYE_STRA3  ;
DR   Q8E284, SYE_STRA5  ;  Q82JR3, SYE_STRAW  ;  O86528, SYE_STRCO  ;
DR   B4U0R8, SYE_STREM  ;  A8AUN5, SYE_STRGC  ;  B1VZ06, SYE_STRGG  ;
DR   B4SPM7, SYE_STRM5  ;  B2FHI7, SYE_STRMK  ;  Q8DVX9, SYE_STRMU  ;
DR   P67023, SYE_STRP1  ;  Q04IA3, SYE_STRP2  ;  P0DG34, SYE_STRP3  ;
DR   B5E378, SYE_STRP4  ;  Q5XDZ4, SYE_STRP6  ;  P67024, SYE_STRP8  ;
DR   Q1JNK7, SYE_STRPC  ;  Q1JIQ6, SYE_STRPD  ;  Q1J8L3, SYE_STRPF  ;
DR   A2RCF4, SYE_STRPG  ;  B1I9D7, SYE_STRPI  ;  Q48VE5, SYE_STRPM  ;
DR   Q97NG1, SYE_STRPN  ;  P0DG35, SYE_STRPQ  ;  B2IMY9, SYE_STRPS  ;
DR   B5XJN3, SYE_STRPZ  ;  Q8CWN5, SYE_STRR6  ;  A4W496, SYE_STRS2  ;
DR   A3CQQ6, SYE_STRSV  ;  A4VY04, SYE_STRSY  ;  Q5LXZ7, SYE_STRT1  ;
DR   Q5M2K1, SYE_STRT2  ;  Q03IP7, SYE_STRTD  ;  Q4J8P2, SYE_SULAC  ;
DR   P95968, SYE_SULSO  ;  B2V5J1, SYE_SULSY  ;  Q971D0, SYE_SULTO  ;
DR   Q67TJ2, SYE_SYMTH  ;  Q8L1E5, SYE_SYNE7  ;  A0LI05, SYE_SYNFM  ;
DR   Q2JRD6, SYE_SYNJA  ;  Q2JKY3, SYE_SYNJB  ;  P31970, SYE_SYNP2  ;
DR   Q5N1B8, SYE_SYNP6  ;  A5GMU7, SYE_SYNPW  ;  Q7U581, SYE_SYNPX  ;
DR   A5GUL0, SYE_SYNR3  ;  Q0I858, SYE_SYNS3  ;  Q3AWM6, SYE_SYNS9  ;
DR   Q3ALW7, SYE_SYNSC  ;  Q55778, SYE_SYNY3  ;  Q9HJM5, SYE_THEAC  ;
DR   Q8DLI5, SYE_THEEB  ;  Q47SA6, SYE_THEFY  ;  B1YAX4, SYE_THENV  ;
DR   B6YSY7, SYE_THEON  ;  A1RYD7, SYE_THEPD  ;  Q72LI9, SYE_THET2  ;
DR   P27000, SYE_THET8  ;  Q979Q0, SYE_THEVO  ;  B5YIG1, SYE_THEYD  ;
DR   Q31GB2, SYE_THICR  ;  Q3SI46, SYE_THIDA  ;  Q43794, SYE_TOBAC  ;
DR   Q73R87, SYE_TREDE  ;  O83679, SYE_TREPA  ;  B2S3R2, SYE_TREPS  ;
DR   Q119Z5, SYE_TRIEI  ;  Q83HJ1, SYE_TROW8  ;  Q83GP4, SYE_TROWT  ;
DR   Q0W8L2, SYE_UNCMA  ;  B1H0J3, SYE_UNCTG  ;  B1AJP0, SYE_UREP2  ;
DR   Q9PPP0, SYE_UREPA  ;  B5ZCB4, SYE_UREU1  ;  A1WN86, SYE_VEREI  ;
DR   A5CWX9, SYE_VESOH  ;  A5F649, SYE_VIBC3  ;  P0C6Q1, SYE_VIBCH  ;
DR   Q5E3L4, SYE_VIBF1  ;  B5FGU2, SYE_VIBFM  ;  A7MY61, SYE_VIBHB  ;
DR   Q87RL6, SYE_VIBPA  ;  Q8DFH5, SYE_VIBVU  ;  Q7MMW8, SYE_VIBVY  ;
DR   Q8D375, SYE_WIGBR  ;  Q8PIP8, SYE_XANAC  ;  Q3BR75, SYE_XANC5  ;
DR   Q4UWS6, SYE_XANC8  ;  B0RQU0, SYE_XANCB  ;  Q8P7C5, SYE_XANCP  ;
DR   Q2P5M8, SYE_XANOM  ;  B2SSC6, SYE_XANOP  ;  Q5H2R3, SYE_XANOR  ;
DR   B2I994, SYE_XYLF2  ;  Q9PF56, SYE_XYLFA  ;  B0U4X9, SYE_XYLFM  ;
DR   Q87AH7, SYE_XYLFT  ;  A1JLB3, SYE_YERE8  ;  A7FGC6, SYE_YERP3  ;
DR   Q1C5Y4, SYE_YERPA  ;  B2K913, SYE_YERPB  ;  Q8ZCK0, SYE_YERPE  ;
DR   A9QZG6, SYE_YERPG  ;  Q1CJV2, SYE_YERPN  ;  A4TMF9, SYE_YERPP  ;
DR   Q668N0, SYE_YERPS  ;  B1JFZ4, SYE_YERPY  ;
//
ID   6.1.1.18
DE   Glutamine--tRNA ligase.
AN   Glutamine translase.
AN   Glutaminyl-tRNA synthetase.
CA   ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-
CA   tRNA(Gln).
PR   PROSITE; PDOC00161;
DR   A6VP11, SYQ_ACTSZ  ;  B6EHL7, SYQ_ALISL  ;  B4RYH7, SYQ_ALTMD  ;
DR   C1DHE5, SYQ_AZOVD  ;  Q2KVX0, SYQ_BORA1  ;  Q7WGA6, SYQ_BORBR  ;
DR   Q7W4T0, SYQ_BORPA  ;  Q7VU94, SYQ_BORPE  ;  Q3MHH4, SYQ_BOVIN  ;
DR   Q89KR6, SYQ_BRAJA  ;  B8D9J3, SYQ_BUCA5  ;  P57490, SYQ_BUCAI  ;
DR   Q8K9E1, SYQ_BUCAP  ;  B8D7U5, SYQ_BUCAT  ;  Q89AD4, SYQ_BUCBP  ;
DR   O62431, SYQ_CAEEL  ;  Q7NX86, SYQ_CHRVO  ;  A8AJD6, SYQ_CITK8  ;
DR   Q188C8, SYQ_CLOD6  ;  A5N6Y3, SYQ_CLOK5  ;  Q0TTG1, SYQ_CLOP1  ;
DR   Q8XMP3, SYQ_CLOPE  ;  Q0SVB1, SYQ_CLOPS  ;  Q47Z40, SYQ_COLP3  ;
DR   Q0K808, SYQ_CUPNH  ;  B3R5N3, SYQ_CUPTR  ;  P56926, SYQ_DEIRA  ;
DR   P14325, SYQ_DICDI  ;  Q9Y105, SYQ_DROME  ;  A7ZJ63, SYQ_ECO24  ;
DR   B7UKW1, SYQ_ECO27  ;  B7MFU7, SYQ_ECO45  ;  B7L9L7, SYQ_ECO55  ;
DR   Q8X9H8, SYQ_ECO57  ;  B5YQM4, SYQ_ECO5E  ;  B7NMN1, SYQ_ECO7I  ;
DR   B7MPI5, SYQ_ECO81  ;  B7M5J8, SYQ_ECO8A  ;  C4ZWF6, SYQ_ECOBW  ;
DR   B1X6L3, SYQ_ECODH  ;  A7ZXU0, SYQ_ECOHS  ;  A1A8U7, SYQ_ECOK1  ;
DR   Q0TK03, SYQ_ECOL5  ;  Q8FJW4, SYQ_ECOL6  ;  B1IY48, SYQ_ECOLC  ;
DR   P00962, SYQ_ECOLI  ;  B7N9S6, SYQ_ECOLU  ;  B6HYN9, SYQ_ECOSE  ;
DR   B1LLC4, SYQ_ECOSM  ;  Q1REN7, SYQ_ECOUT  ;  C5BGA4, SYQ_EDWI9  ;
DR   Q8SR10, SYQ_ENCCU  ;  A4W846, SYQ_ENT38  ;  A9CSU5, SYQ_ENTBH  ;
DR   A7MQT2, SYQ_ENTS8  ;  Q6D7J7, SYQ_ERWCT  ;  B2VBN3, SYQ_ERWT9  ;
DR   B7LKT3, SYQ_ESCF3  ;  Q7VLM3, SYQ_HAEDU  ;  Q4QK64, SYQ_HAEI8  ;
DR   P43831, SYQ_HAEIN  ;  C4K4J9, SYQ_HAMD5  ;  P47897, SYQ_HUMAN  ;
DR   Q5QXQ2, SYQ_IDILO  ;  B5XZG7, SYQ_KLEP3  ;  A6T6C3, SYQ_KLEP7  ;
DR   P52780, SYQ_LUPLU  ;  Q5F7G0, SYQ_NEIG1  ;  P57000, SYQ_NEIMA  ;
DR   P56927, SYQ_NEIMB  ;  Q81ZS7, SYQ_NITEU  ;  Q1QMM1, SYQ_NITHX  ;
DR   Q3SRI8, SYQ_NITWN  ;  C4V819, SYQ_NOSCE  ;  P57847, SYQ_PASMU  ;
DR   C6DBY6, SYQ_PECCP  ;  Q7N743, SYQ_PHOLL  ;  Q6LTD1, SYQ_PHOPR  ;
DR   B1XW11, SYQ_POLNS  ;  A4SZM1, SYQ_POLSQ  ;  B4EV71, SYQ_PROMH  ;
DR   Q15TT6, SYQ_PSEA6  ;  B7VB85, SYQ_PSEA8  ;  Q02KT5, SYQ_PSEAB  ;
DR   Q9I2U8, SYQ_PSEAE  ;  Q3IGW8, SYQ_PSEHT  ;  A4XVG2, SYQ_PSEMY  ;
DR   Q88IU5, SYQ_PSEPK  ;  Q87YQ1, SYQ_PSESM  ;  A4VL72, SYQ_PSEU5  ;
DR   A1SS83, SYQ_PSYIN  ;  Q1LQ72, SYQ_RALME  ;  B2U846, SYQ_RALPJ  ;
DR   Q8Y199, SYQ_RALSO  ;  Q7UX42, SYQ_RHOBA  ;  B5EZC3, SYQ_SALA4  ;
DR   A9MKA7, SYQ_SALAR  ;  Q57RP8, SYQ_SALCH  ;  B5FNC1, SYQ_SALDC  ;
DR   B5QWD0, SYQ_SALEP  ;  B5R651, SYQ_SALG2  ;  B4TB84, SYQ_SALHS  ;
DR   B4SYN9, SYQ_SALNS  ;  Q5PCH8, SYQ_SALPA  ;  A9MUG5, SYQ_SALPB  ;
DR   C0PWA7, SYQ_SALPC  ;  B5BCC3, SYQ_SALPK  ;  B4TQ00, SYQ_SALSV  ;
DR   Q8Z8F8, SYQ_SALTI  ;  Q8ZQX5, SYQ_SALTY  ;  Q9Y7Y8, SYQ_SCHPO  ;
DR   A8GB43, SYQ_SERP5  ;  Q8EG26, SYQ_SHEON  ;  B2TU51, SYQ_SHIB3  ;
DR   Q324M4, SYQ_SHIBS  ;  Q32IQ0, SYQ_SHIDS  ;  Q0T6S8, SYQ_SHIF8  ;
DR   Q83LY4, SYQ_SHIFL  ;  Q3Z4C0, SYQ_SHISS  ;  Q2NUP0, SYQ_SODGM  ;
DR   C4L887, SYQ_TOLAT  ;  A5F2T1, SYQ_VIBC3  ;  Q9KTA6, SYQ_VIBCH  ;
DR   C3LTP5, SYQ_VIBCM  ;  Q5E6P2, SYQ_VIBF1  ;  B5FC12, SYQ_VIBFM  ;
DR   A7MT45, SYQ_VIBHB  ;  Q87RG4, SYQ_VIBPA  ;  B7VIH6, SYQ_VIBSL  ;
DR   Q7MMQ4, SYQ_VIBVY  ;  Q8PNZ5, SYQ_XANAC  ;  Q3BX52, SYQ_XANC5  ;
DR   Q4UR70, SYQ_XANC8  ;  Q8PCB3, SYQ_XANCP  ;  Q2NZL7, SYQ_XANOM  ;
DR   Q5GWF4, SYQ_XANOR  ;  Q9PDP1, SYQ_XYLFA  ;  B0U6D0, SYQ_XYLFM  ;
DR   Q87DU6, SYQ_XYLFT  ;  P13188, SYQ_YEAST  ;  A1JQH0, SYQ_YERE8  ;
DR   A7FKU1, SYQ_YERP3  ;  Q1C540, SYQ_YERPA  ;  B2K8A4, SYQ_YERPB  ;
DR   Q8ZDD9, SYQ_YERPE  ;  A9R7G5, SYQ_YERPG  ;  Q1CKN4, SYQ_YERPN  ;
DR   A4TNX8, SYQ_YERPP  ;  Q66DC5, SYQ_YERPS  ;  B1JG85, SYQ_YERPY  ;
//
ID   6.1.1.19
DE   Arginine--tRNA ligase.
AN   Arginine translase.
AN   Arginyl-tRNA synthetase.
CA   ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).
PR   PROSITE; PDOC00161;
DR   Q81JT7, SYR1_BACAN ;  Q63C01, SYR1_BACCZ ;  Q9K6C1, SYR1_BACHD ;
DR   Q6HJF5, SYR1_BACHK ;  Q81R81, SYR2_BACAN ;  Q630N6, SYR2_BACCZ ;
DR   Q9KEL8, SYR2_BACHD ;  Q6HAS1, SYR2_BACHK ;  A7YW98, SYRC_BOVIN ;
DR   Q19825, SYRC_CAEEL ;  Q5ZM11, SYRC_CHICK ;  P37880, SYRC_CRIGR ;
DR   Q558Z0, SYRC_DICDI ;  Q9VXN4, SYRC_DROME ;  P54136, SYRC_HUMAN ;
DR   Q9D0I9, SYRC_MOUSE ;  Q5RA20, SYRC_PONAB ;  P40329, SYRC_RAT   ;
DR   O74781, SYRC_SCHPO ;  Q6P1S4, SYRC_XENTR ;  Q05506, SYRC_YEAST ;
DR   Q0P5H7, SYRM_BOVIN ;  Q5T160, SYRM_HUMAN ;  Q3U186, SYRM_MOUSE ;
DR   Q5REH3, SYRM_PONAB ;  Q6GQJ7, SYRM_XENLA ;  P38714, SYRM_YEAST ;
DR   A1TJ83, SYR_ACIAC  ;  Q6FFM0, SYR_ACIAD  ;  B7H2A9, SYR_ACIB3  ;
DR   B7I1U9, SYR_ACIB5  ;  B2I0Y7, SYR_ACIBC  ;  B0VNJ1, SYR_ACIBS  ;
DR   B0VBN5, SYR_ACIBY  ;  B9MBD2, SYR_ACIET  ;  B7J3R6, SYR_ACIF2  ;
DR   B5EL87, SYR_ACIF5  ;  A6VNB3, SYR_ACTSZ  ;  Q9YB39, SYR_AERPE  ;
DR   B9JEG3, SYR_AGRRK  ;  Q8UEP4, SYR_AGRT5  ;  B9JXE6, SYR_AGRVS  ;
DR   Q0VMA8, SYR_ALCBS  ;  B6EI57, SYR_ALISL  ;  A6TNX2, SYR_ALKMQ  ;
DR   A8MKD9, SYR_ALKOO  ;  B4RU34, SYR_ALTMD  ;  B3ERZ8, SYR_AMOA5  ;
DR   B8JBE2, SYR_ANAD2  ;  Q2II14, SYR_ANADE  ;  A7HCP4, SYR_ANADF  ;
DR   Q5PAM4, SYR_ANAMM  ;  Q2GK20, SYR_ANAPZ  ;  B4UEJ9, SYR_ANASK  ;
DR   Q3M769, SYR_ANAVT  ;  B7GMJ3, SYR_ANOFW  ;  O67068, SYR_AQUAE  ;
DR   A8EWM0, SYR_ARCB4  ;  O29368, SYR_ARCFU  ;  Q5P3E7, SYR_AROAE  ;
DR   A1R7X2, SYR_ARTAT  ;  B8HB09, SYR_ARTCA  ;  A8I9L7, SYR_AZOC5  ;
DR   A1K2E2, SYR_AZOSB  ;  C1DHR7, SYR_AZOVD  ;  A7Z9V1, SYR_BACA2  ;
DR   Q72X85, SYR_BACC1  ;  Q814Q8, SYR_BACCR  ;  Q5L7Q8, SYR_BACFN  ;
DR   Q64MX8, SYR_BACFR  ;  Q65DS9, SYR_BACLD  ;  A8FIG8, SYR_BACP2  ;
DR   Q5WB34, SYR_BACSK  ;  P46906, SYR_BACSU  ;  Q8A3X5, SYR_BACTN  ;
DR   A6KZA8, SYR_BACV8  ;  A1USU3, SYR_BARBK  ;  Q6G316, SYR_BARHE  ;
DR   Q6FZH0, SYR_BARQU  ;  A9IVK4, SYR_BART1  ;  Q1LTI8, SYR_BAUCH  ;
DR   Q6MLI2, SYR_BDEBA  ;  B2IJG9, SYR_BEII9  ;  B8DWR0, SYR_BIFA0  ;
DR   A1A3B6, SYR_BIFAA  ;  B3DPJ1, SYR_BIFLD  ;  Q8G4V2, SYR_BIFLO  ;
DR   B7GNM0, SYR_BIFLS  ;  Q7VQX7, SYR_BLOFL  ;  Q492L0, SYR_BLOPB  ;
DR   Q2KTN9, SYR_BORA1  ;  Q0SMR4, SYR_BORAP  ;  Q7WDQ0, SYR_BORBR  ;
DR   O51540, SYR_BORBU  ;  B5RME6, SYR_BORDL  ;  Q660S8, SYR_BORGA  ;
DR   B2S0U2, SYR_BORHD  ;  Q7W2Q2, SYR_BORPA  ;  A9HVX4, SYR_BORPD  ;
DR   Q7W0K0, SYR_BORPE  ;  B5RPU2, SYR_BORRA  ;  A1R025, SYR_BORT9  ;
DR   C0R2B0, SYR_BRAHW  ;  A5EJW7, SYR_BRASB  ;  A4YV78, SYR_BRASO  ;
DR   B2S5B0, SYR_BRUA1  ;  Q2YNJ9, SYR_BRUA2  ;  Q57DN0, SYR_BRUAB  ;
DR   A9MAQ0, SYR_BRUC2  ;  C0RIL0, SYR_BRUMB  ;  Q8YGR9, SYR_BRUME  ;
DR   A5VQ54, SYR_BRUO2  ;  B0CLK2, SYR_BRUSI  ;  Q8G146, SYR_BRUSU  ;
DR   B8D940, SYR_BUCA5  ;  Q44683, SYR_BUCAI  ;  Q08888, SYR_BUCAP  ;
DR   B8D7E4, SYR_BUCAT  ;  P59483, SYR_BUCBP  ;  Q057S1, SYR_BUCCC  ;
DR   B1YNQ7, SYR_BURA4  ;  Q1BT49, SYR_BURCA  ;  B1JZC6, SYR_BURCC  ;
DR   A0KAZ0, SYR_BURCH  ;  B4E9M9, SYR_BURCJ  ;  Q0BBE9, SYR_BURCM  ;
DR   A9AE58, SYR_BURM1  ;  A3MNI3, SYR_BURM7  ;  A2S7P3, SYR_BURM9  ;
DR   Q62MY7, SYR_BURMA  ;  A1V839, SYR_BURMS  ;  A3NQU2, SYR_BURP0  ;
DR   Q3JWP7, SYR_BURP1  ;  A3N542, SYR_BURP6  ;  B2JKJ2, SYR_BURP8  ;
DR   B2SWV4, SYR_BURPP  ;  Q63Y06, SYR_BURPS  ;  Q39CG0, SYR_BURS3  ;
DR   Q2T1N6, SYR_BURTA  ;  A4JIA2, SYR_BURVG  ;  Q146I4, SYR_BURXL  ;
DR   A7ZF21, SYR_CAMC1  ;  A7GWS5, SYR_CAMC5  ;  A0RQU0, SYR_CAMFF  ;
DR   A8FMN1, SYR_CAMJ8  ;  A7H2J9, SYR_CAMJD  ;  Q9PNC0, SYR_CAMJE  ;
DR   A1W0F9, SYR_CAMJJ  ;  Q5HTT9, SYR_CAMJR  ;  B9KCX0, SYR_CAMLR  ;
DR   Q3AFT8, SYR_CARHZ  ;  B8H4W0, SYR_CAUCN  ;  Q9A347, SYR_CAUCR  ;
DR   B0T019, SYR_CAUSK  ;  B3PKE3, SYR_CELJU  ;  A9WEH7, SYR_CHLAA  ;
DR   Q5L6U4, SYR_CHLAB  ;  B8G4J9, SYR_CHLAD  ;  Q3ANY2, SYR_CHLCH  ;
DR   Q824H4, SYR_CHLCV  ;  Q253D1, SYR_CHLFF  ;  B3EIJ1, SYR_CHLL2  ;
DR   Q9PJT8, SYR_CHLMU  ;  B3QLU7, SYR_CHLP8  ;  B3EQ83, SYR_CHLPB  ;
DR   A1BJV9, SYR_CHLPD  ;  Q9Z7Y3, SYR_CHLPN  ;  B9LGY2, SYR_CHLSY  ;
DR   Q3KLP4, SYR_CHLTA  ;  Q8KGF3, SYR_CHLTE  ;  O84460, SYR_CHLTR  ;
DR   Q1QZZ4, SYR_CHRSD  ;  Q7NWM1, SYR_CHRVO  ;  A8AFG5, SYR_CITK8  ;
DR   B0RAP7, SYR_CLAMS  ;  Q97K78, SYR_CLOAB  ;  A7FSW7, SYR_CLOB1  ;
DR   C3KSZ0, SYR_CLOB6  ;  A6LS73, SYR_CLOB8  ;  B2UW74, SYR_CLOBA  ;
DR   A5I0R5, SYR_CLOBH  ;  C1FK28, SYR_CLOBJ  ;  B1IIE6, SYR_CLOBK  ;
DR   A7GCB9, SYR_CLOBL  ;  B1KYT1, SYR_CLOBM  ;  B8I592, SYR_CLOCE  ;
DR   Q189Q7, SYR_CLOD6  ;  B9E1W5, SYR_CLOK1  ;  A5N8F9, SYR_CLOK5  ;
DR   Q8XJU2, SYR_CLOPE  ;  Q896N5, SYR_CLOTE  ;  A3DGS4, SYR_CLOTH  ;
DR   Q487B1, SYR_COLP3  ;  C3PFN8, SYR_CORA7  ;  Q6NHU6, SYR_CORDI  ;
DR   Q8FQ57, SYR_COREF  ;  A4QDE1, SYR_CORGB  ;  P35868, SYR_CORGL  ;
DR   Q4JUI1, SYR_CORJK  ;  B6J667, SYR_COXB1  ;  B6J3D4, SYR_COXB2  ;
DR   A9KH27, SYR_COXBN  ;  A9N9G2, SYR_COXBR  ;  Q83A98, SYR_COXBU  ;
DR   Q0KFB0, SYR_CUPNH  ;  Q477C4, SYR_CUPPJ  ;  B2AG76, SYR_CUPTR  ;
DR   B1X0N5, SYR_CYAA5  ;  B8HSK8, SYR_CYAP4  ;  B7KCT7, SYR_CYAP7  ;
DR   B7JVP5, SYR_CYAP8  ;  Q478Y7, SYR_DECAR  ;  Q3Z717, SYR_DEHE1  ;
DR   A5FQ65, SYR_DEHSB  ;  Q3ZYF0, SYR_DEHSC  ;  Q9RRC4, SYR_DEIRA  ;
DR   A9BRF4, SYR_DELAS  ;  B8FCL2, SYR_DESAA  ;  C6BU27, SYR_DESAD  ;
DR   C0QKZ8, SYR_DESAH  ;  B1I6Q5, SYR_DESAP  ;  B8IYS4, SYR_DESDA  ;
DR   Q30Z04, SYR_DESDG  ;  B8FZ89, SYR_DESHD  ;  Q24MK7, SYR_DESHY  ;
DR   C4XSX9, SYR_DESMR  ;  A9A099, SYR_DESOH  ;  Q6AJJ9, SYR_DESPS  ;
DR   A4J9D2, SYR_DESRM  ;  Q72CN5, SYR_DESVH  ;  B8DNX4, SYR_DESVM  ;
DR   A1VEG5, SYR_DESVV  ;  A5EXU4, SYR_DICNV  ;  A7ZN02, SYR_ECO24  ;
DR   B7USQ3, SYR_ECO27  ;  B7MBT5, SYR_ECO45  ;  B7L7S9, SYR_ECO55  ;
DR   Q8XCH2, SYR_ECO57  ;  B5YR22, SYR_ECO5E  ;  B7NS42, SYR_ECO7I  ;
DR   B7MW70, SYR_ECO81  ;  B7M2G7, SYR_ECO8A  ;  C4ZQG0, SYR_ECOBW  ;
DR   B1XHE4, SYR_ECODH  ;  A8A178, SYR_ECOHS  ;  A1AC37, SYR_ECOK1  ;
DR   Q0TGV6, SYR_ECOL5  ;  Q8FGQ0, SYR_ECOL6  ;  B1J0L2, SYR_ECOLC  ;
DR   P11875, SYR_ECOLI  ;  B7NBM7, SYR_ECOLU  ;  B6I0S7, SYR_ECOSE  ;
DR   B1LCZ5, SYR_ECOSM  ;  Q1RAQ8, SYR_ECOUT  ;  C5B832, SYR_EDWI9  ;
DR   Q3YRX1, SYR_EHRCJ  ;  Q2GGT3, SYR_EHRCR  ;  Q5FH87, SYR_EHRRG  ;
DR   Q5HB39, SYR_EHRRW  ;  B2KD56, SYR_ELUMP  ;  Q8SRD8, SYR_ENCCU  ;
DR   A4WBN1, SYR_ENT38  ;  Q831N1, SYR_ENTFA  ;  A7MEC0, SYR_ENTS8  ;
DR   Q6D474, SYR_ERWCT  ;  B2VJB6, SYR_ERWT9  ;  B7LPH0, SYR_ESCF3  ;
DR   C4ZD15, SYR_EUBR3  ;  B1YFI1, SYR_EXIS2  ;  C4L0Z5, SYR_EXISA  ;
DR   A5FND6, SYR_FLAJ1  ;  A6GZP8, SYR_FLAPJ  ;  Q0RD93, SYR_FRAAA  ;
DR   Q2J9H6, SYR_FRASC  ;  A8L3U5, SYR_FRASN  ;  Q14IZ0, SYR_FRAT1  ;
DR   A7NDV6, SYR_FRATF  ;  Q2A215, SYR_FRATH  ;  B2SDQ4, SYR_FRATM  ;
DR   A0Q5D7, SYR_FRATN  ;  Q0BKP4, SYR_FRATO  ;  Q5NHI8, SYR_FRATT  ;
DR   A4IZF4, SYR_FRATW  ;  Q8RG14, SYR_FUSNN  ;  B5EEF0, SYR_GEOBB  ;
DR   Q5KUF0, SYR_GEOKA  ;  Q39VQ6, SYR_GEOMG  ;  B9M2S2, SYR_GEOSF  ;
DR   Q74C63, SYR_GEOSL  ;  C6E805, SYR_GEOSM  ;  C5D9R0, SYR_GEOSW  ;
DR   A4ITM9, SYR_GEOTN  ;  A5G3W5, SYR_GEOUR  ;  Q7NDF6, SYR_GLOVI  ;
DR   Q5FQ54, SYR_GLUOX  ;  Q7VP38, SYR_HAEDU  ;  Q4QL12, SYR_HAEI8  ;
DR   A5UCH1, SYR_HAEIE  ;  A5UJ40, SYR_HAEIG  ;  P43832, SYR_HAEIN  ;
DR   Q0I3B0, SYR_HAES1  ;  B0UUF1, SYR_HAES2  ;  Q2SMY0, SYR_HAHCH  ;
DR   A1WZR7, SYR_HALHL  ;  B9LRF1, SYR_HALLT  ;  Q5UXX8, SYR_HALMA  ;
DR   B8CWA9, SYR_HALOH  ;  Q9HHN2, SYR_HALSA  ;  Q18FC1, SYR_HALWD  ;
DR   C4K487, SYR_HAMD5  ;  Q17X54, SYR_HELAH  ;  Q7VI99, SYR_HELHP  ;
DR   B0TI89, SYR_HELMI  ;  B6JKP5, SYR_HELP2  ;  B5ZA86, SYR_HELPG  ;
DR   Q1CUI3, SYR_HELPH  ;  Q9ZMB9, SYR_HELPJ  ;  B2USE8, SYR_HELPS  ;
DR   P56128, SYR_HELPY  ;  A4G1E2, SYR_HERAR  ;  Q0BYP8, SYR_HYPNA  ;
DR   Q5QV46, SYR_IDILO  ;  A8AB06, SYR_IGNH4  ;  A6SU56, SYR_JANMA  ;
DR   Q28S88, SYR_JANSC  ;  A6W7E9, SYR_KINRD  ;  B5XPZ2, SYR_KLEP3  ;
DR   A6TB43, SYR_KLEP7  ;  B2GLW8, SYR_KOCRD  ;  B1L3E4, SYR_KORCO  ;
DR   Q5FIQ9, SYR_LACAC  ;  Q03QD4, SYR_LACBA  ;  Q1GAN1, SYR_LACDA  ;
DR   Q04B18, SYR_LACDB  ;  B2GDD7, SYR_LACF3  ;  Q74KR5, SYR_LACJO  ;
DR   Q9CE12, SYR_LACLA  ;  A2RNI8, SYR_LACLM  ;  Q02W95, SYR_LACLS  ;
DR   Q88X53, SYR_LACPL  ;  A5VL03, SYR_LACRD  ;  B2G8D8, SYR_LACRJ  ;
DR   Q1WU48, SYR_LACS1  ;  Q38VQ9, SYR_LACSS  ;  C1D5W4, SYR_LARHH  ;
DR   Q1MRU1, SYR_LAWIP  ;  Q5X3M1, SYR_LEGPA  ;  A5IDL4, SYR_LEGPC  ;
DR   Q5ZTX7, SYR_LEGPH  ;  Q5WV09, SYR_LEGPL  ;  Q6AG81, SYR_LEIXX  ;
DR   B0SB29, SYR_LEPBA  ;  Q04TG2, SYR_LEPBJ  ;  Q052J1, SYR_LEPBL  ;
DR   B0SSV1, SYR_LEPBP  ;  B1XYP5, SYR_LEPCP  ;  Q72QL1, SYR_LEPIC  ;
DR   Q8F5J3, SYR_LEPIN  ;  B1MZ82, SYR_LEUCK  ;  Q03WV9, SYR_LEUMM  ;
DR   Q927T2, SYR_LISIN  ;  C1KYX7, SYR_LISMC  ;  Q71WL8, SYR_LISMF  ;
DR   B8DBE8, SYR_LISMH  ;  Q8Y493, SYR_LISMO  ;  A0ALP7, SYR_LISW6  ;
DR   Q2W492, SYR_MAGSA  ;  A0L5I2, SYR_MAGSM  ;  Q65SX3, SYR_MANSM  ;
DR   A1TYU8, SYR_MARAV  ;  Q0AMI8, SYR_MARMM  ;  A6W2V1, SYR_MARMS  ;
DR   Q6F0R1, SYR_MESFL  ;  Q11HB8, SYR_MESSB  ;  A6UW07, SYR_META3  ;
DR   Q8TUM3, SYR_METAC  ;  A7I4Y2, SYR_METB6  ;  Q46DR6, SYR_METBF  ;
DR   Q12V97, SYR_METBU  ;  B7KWG7, SYR_METC4  ;  Q602H4, SYR_METCA  ;
DR   A9W7L3, SYR_METEP  ;  Q2FS66, SYR_METHJ  ;  Q57689, SYR_METJA  ;
DR   Q8TXB6, SYR_METKA  ;  A2STL6, SYR_METLZ  ;  A4FXF3, SYR_METM5  ;
DR   A9AAS2, SYR_METM6  ;  A6VFW2, SYR_METM7  ;  Q8PX74, SYR_METMA  ;
DR   Q6LYG5, SYR_METMP  ;  B8I9T2, SYR_METNO  ;  B8GJL7, SYR_METPE  ;
DR   A2SC26, SYR_METPP  ;  B1M335, SYR_METRJ  ;  A5UMK8, SYR_METS3  ;
DR   B0UI81, SYR_METS4  ;  Q2NE12, SYR_METST  ;  O27496, SYR_METTH  ;
DR   A0B5P0, SYR_METTP  ;  A6UP37, SYR_METVS  ;  B0JLI8, SYR_MICAN  ;
DR   C5CA60, SYR_MICLC  ;  Q5UQ59, SYR_MIMIV  ;  Q2RFU7, SYR_MOOTA  ;
DR   B3PM19, SYR_MYCA5  ;  B1MLU2, SYR_MYCA9  ;  P67570, SYR_MYCBO  ;
DR   A1KI80, SYR_MYCBP  ;  C1AMT6, SYR_MYCBT  ;  Q2SSA3, SYR_MYCCT  ;
DR   Q7NC67, SYR_MYCGA  ;  P47618, SYR_MYCGE  ;  A4T8M4, SYR_MYCGI  ;
DR   Q602D8, SYR_MYCH2  ;  Q4A900, SYR_MYCH7  ;  Q4AAT7, SYR_MYCHJ  ;
DR   B8ZR24, SYR_MYCLB  ;  P45840, SYR_MYCLE  ;  B2HR81, SYR_MYCMM  ;
DR   Q6KIG6, SYR_MYCMO  ;  Q6MT14, SYR_MYCMS  ;  Q73X40, SYR_MYCPA  ;
DR   Q8EVF2, SYR_MYCPE  ;  P75222, SYR_MYCPN  ;  Q9X5M0, SYR_MYCS2  ;
DR   A3Q3D3, SYR_MYCSJ  ;  A1UK06, SYR_MYCSK  ;  Q1B531, SYR_MYCSS  ;
DR   A5U1Z1, SYR_MYCTA  ;  P67569, SYR_MYCTU  ;  A0PUL8, SYR_MYCUA  ;
DR   A1TD77, SYR_MYCVP  ;  Q3IUQ6, SYR_NATPD  ;  B9L8B8, SYR_NAUPA  ;
DR   Q5F835, SYR_NEIG1  ;  B4RL22, SYR_NEIG2  ;  Q9JTM7, SYR_NEIMA  ;
DR   Q9JYM8, SYR_NEIMB  ;  A1KUU4, SYR_NEIMF  ;  Q2GEZ6, SYR_NEOSM  ;
DR   Q0AFN4, SYR_NITEC  ;  Q82XC1, SYR_NITEU  ;  Q1QMH5, SYR_NITHX  ;
DR   Q2Y676, SYR_NITMU  ;  Q3JF27, SYR_NITOC  ;  A6Q543, SYR_NITSB  ;
DR   Q3SRM3, SYR_NITWN  ;  Q5Z0Z9, SYR_NOCFA  ;  B2J6I0, SYR_NOSP7  ;
DR   Q8YQU9, SYR_NOSS1  ;  Q2G9D9, SYR_NOVAD  ;  Q8EM45, SYR_OCEIH  ;
DR   A6X1G1, SYR_OCHA4  ;  Q04FF6, SYR_OENOB  ;  A5CD00, SYR_ORITB  ;
DR   B3CST6, SYR_ORITI  ;  A6LHY5, SYR_PARD8  ;  A1B373, SYR_PARDP  ;
DR   A7HXJ6, SYR_PARL1  ;  Q6MEP4, SYR_PARUW  ;  P57851, SYR_PASMU  ;
DR   C6DFD9, SYR_PECCP  ;  Q03GE2, SYR_PEDPA  ;  Q3A6K6, SYR_PELCD  ;
DR   Q3B147, SYR_PELLD  ;  B4SH34, SYR_PELPB  ;  Q4FM10, SYR_PELUB  ;
DR   B4R8T9, SYR_PHEZH  ;  Q7N565, SYR_PHOLL  ;  Q6LTA1, SYR_PHOPR  ;
DR   A1VTL9, SYR_POLNA  ;  B1XSF4, SYR_POLNS  ;  Q123B6, SYR_POLSJ  ;
DR   B2RHN9, SYR_PORG3  ;  Q7MXD5, SYR_PORGI  ;  B4S6D8, SYR_PROA2  ;
DR   Q6A5X8, SYR_PROAC  ;  A2C016, SYR_PROM1  ;  A2CDB7, SYR_PROM3  ;
DR   A9BDF0, SYR_PROM4  ;  Q31CZ4, SYR_PROM9  ;  Q7VE03, SYR_PROMA  ;
DR   B4ETN5, SYR_PROMH  ;  Q7V493, SYR_PROMM  ;  Q7V396, SYR_PROMP  ;
DR   Q46HI6, SYR_PROMT  ;  A4SGY3, SYR_PROVI  ;  Q48PI2, SYR_PSE14  ;
DR   Q15W53, SYR_PSEA6  ;  A6VDH2, SYR_PSEA7  ;  B7V3E4, SYR_PSEA8  ;
DR   Q02EW6, SYR_PSEAB  ;  Q9HUC8, SYR_PSEAE  ;  Q1IGB8, SYR_PSEE4  ;
DR   Q4KJK0, SYR_PSEF5  ;  C3KAH3, SYR_PSEFS  ;  Q3IHI4, SYR_PSEHT  ;
DR   A4XPN9, SYR_PSEMY  ;  A5WAC2, SYR_PSEP1  ;  Q3KJB3, SYR_PSEPF  ;
DR   B0KN43, SYR_PSEPG  ;  Q88CU1, SYR_PSEPK  ;  B1J2I3, SYR_PSEPW  ;
DR   Q87V03, SYR_PSESM  ;  Q4ZZF5, SYR_PSEU2  ;  A4VH02, SYR_PSEU5  ;
DR   Q4FQB4, SYR_PSYA2  ;  Q1Q8I7, SYR_PSYCK  ;  A1SQW6, SYR_PSYIN  ;
DR   A5WC58, SYR_PSYWF  ;  Q9V0V2, SYR_PYRAB  ;  Q8ZTA8, SYR_PYRAE  ;
DR   A4WLP0, SYR_PYRAR  ;  Q8U149, SYR_PYRFU  ;  O59147, SYR_PYRHO  ;
DR   A1RS32, SYR_PYRIL  ;  Q5JGH7, SYR_PYRKO  ;  Q1LS94, SYR_RALME  ;
DR   B2UDW0, SYR_RALPJ  ;  Q8Y2P8, SYR_RALSO  ;  A9WNA7, SYR_RENSM  ;
DR   B3PXT5, SYR_RHIE6  ;  Q2K975, SYR_RHIEC  ;  Q98LC0, SYR_RHILO  ;
DR   B5ZMF2, SYR_RHILW  ;  Q92Q31, SYR_RHIME  ;  Q7URC7, SYR_RHOBA  ;
DR   C1A1Z7, SYR_RHOE4  ;  Q220N0, SYR_RHOFD  ;  C1AW17, SYR_RHOOB  ;
DR   Q2IWF8, SYR_RHOP2  ;  Q6N5W6, SYR_RHOPA  ;  Q214X7, SYR_RHOPB  ;
DR   Q2RTG6, SYR_RHORT  ;  A3PK32, SYR_RHOS1  ;  Q3J281, SYR_RHOS4  ;
DR   A4WQZ1, SYR_RHOS5  ;  B9KSX6, SYR_RHOSK  ;  Q0SGN1, SYR_RHOSR  ;
DR   C3PMA4, SYR_RICAE  ;  A8GM09, SYR_RICAH  ;  A8GUI1, SYR_RICB8  ;
DR   Q1RGY1, SYR_RICBR  ;  A8EXD2, SYR_RICCK  ;  Q92JH2, SYR_RICCN  ;
DR   Q4UN98, SYR_RICFE  ;  Q9ZE81, SYR_RICPR  ;  C4K184, SYR_RICPU  ;
DR   B0BW17, SYR_RICRO  ;  A8GQM8, SYR_RICRS  ;  Q68XT9, SYR_RICTY  ;
DR   Q164C1, SYR_ROSDO  ;  A1AVC2, SYR_RUTMC  ;  Q21I40, SYR_SACD2  ;
DR   A4FN47, SYR_SACEN  ;  B5F3I0, SYR_SALA4  ;  A9MNC4, SYR_SALAR  ;
DR   Q57N89, SYR_SALCH  ;  B5FSM1, SYR_SALDC  ;  B5R142, SYR_SALEP  ;
DR   B5R8C8, SYR_SALG2  ;  B4T808, SYR_SALHS  ;  B4SVG0, SYR_SALNS  ;
DR   Q5PMZ2, SYR_SALPA  ;  A9MUA9, SYR_SALPB  ;  B5BH46, SYR_SALPK  ;
DR   Q2S3W3, SYR_SALRD  ;  B4TYT3, SYR_SALSV  ;  Q8Z5V7, SYR_SALTI  ;
DR   E1WGF0, SYR_SALTS  ;  P0CL51, SYR_SALTY  ;  A8GFK2, SYR_SERP5  ;
DR   A1S2P7, SYR_SHEAM  ;  B8E6G9, SYR_SHEB2  ;  A3D9A3, SYR_SHEB5  ;
DR   A6WIK3, SYR_SHEB8  ;  A9KYS9, SYR_SHEB9  ;  Q12IU3, SYR_SHEDO  ;
DR   Q07WM5, SYR_SHEFN  ;  B0TVV1, SYR_SHEHH  ;  A3Q9V2, SYR_SHELP  ;
DR   Q8E9Y7, SYR_SHEON  ;  A8H953, SYR_SHEPA  ;  A4Y2U9, SYR_SHEPC  ;
DR   B8CI29, SYR_SHEPW  ;  A0L1H3, SYR_SHESA  ;  A8FQM2, SYR_SHESH  ;
DR   Q0HEF5, SYR_SHESM  ;  Q0HZJ6, SYR_SHESR  ;  A1RP36, SYR_SHESW  ;
DR   B1KK48, SYR_SHEWM  ;  B2U4X7, SYR_SHIB3  ;  Q322J5, SYR_SHIBS  ;
DR   Q32H69, SYR_SHIDS  ;  Q0T3Q1, SYR_SHIF8  ;  Q83KQ3, SYR_SHIFL  ;
DR   Q3Z2Q4, SYR_SHISS  ;  Q5LQI6, SYR_SILPO  ;  Q1GI80, SYR_SILST  ;
DR   A6U8M9, SYR_SINMW  ;  Q2NTK2, SYR_SODGM  ;  A7WZ56, SYR_STAA1  ;
DR   A6TZ85, SYR_STAA2  ;  Q2FJ29, SYR_STAA3  ;  Q2G0F8, SYR_STAA8  ;
DR   A5IQG1, SYR_STAA9  ;  Q2YSW8, SYR_STAAB  ;  Q5HI60, SYR_STAAC  ;
DR   A6QER9, SYR_STAAE  ;  Q932F6, SYR_STAAM  ;  Q99W05, SYR_STAAN  ;
DR   Q6GJ61, SYR_STAAR  ;  Q6GBM1, SYR_STAAS  ;  A8Z117, SYR_STAAT  ;
DR   Q8NXT8, SYR_STAAW  ;  B9DKQ7, SYR_STACT  ;  Q5HRD1, SYR_STAEQ  ;
DR   Q8CTN9, SYR_STAES  ;  Q4L425, SYR_STAHJ  ;  Q49VF3, SYR_STAS1  ;
DR   Q3JYM1, SYR_STRA1  ;  Q8E2R1, SYR_STRA3  ;  Q8DWV9, SYR_STRA5  ;
DR   Q82E68, SYR_STRAW  ;  Q9WX29, SYR_STRCO  ;  C0MAS8, SYR_STRE4  ;
DR   B1VTB7, SYR_STRGG  ;  B4STE2, SYR_STRM5  ;  B2FJW0, SYR_STRMK  ;
DR   Q8DRW2, SYR_STRMU  ;  Q99XL5, SYR_STRP1  ;  Q04I94, SYR_STRP2  ;
DR   P0DG26, SYR_STRP3  ;  B5E387, SYR_STRP4  ;  Q5X9F1, SYR_STRP6  ;
DR   C1CAQ7, SYR_STRP7  ;  Q8NZ22, SYR_STRP8  ;  Q1J9B9, SYR_STRPB  ;
DR   Q1JJG7, SYR_STRPC  ;  Q1JEG8, SYR_STRPD  ;  Q1J486, SYR_STRPF  ;
DR   A2RGX5, SYR_STRPG  ;  B1I9E7, SYR_STRPI  ;  B8ZPK2, SYR_STRPJ  ;
DR   Q48QT3, SYR_STRPM  ;  Q54869, SYR_STRPN  ;  P0DG27, SYR_STRPQ  ;
DR   B2IMZ8, SYR_STRPS  ;  B5XJ77, SYR_STRPZ  ;  Q8DN69, SYR_STRR6  ;
DR   A4W4J9, SYR_STRS2  ;  C0MGC8, SYR_STRS7  ;  A4VYA3, SYR_STRSY  ;
DR   Q5M1Z3, SYR_STRT1  ;  Q5M6I4, SYR_STRT2  ;  Q03MY7, SYR_STRTD  ;
DR   B9DW76, SYR_STRU0  ;  C1CH08, SYR_STRZJ  ;  C1CN25, SYR_STRZP  ;
DR   C1CTY4, SYR_STRZT  ;  Q4J904, SYR_SULAC  ;  Q30PL3, SYR_SULDN  ;
DR   Q97ZN1, SYR_SULSO  ;  Q971X1, SYR_SULTO  ;  Q67TI9, SYR_SYMTH  ;
DR   Q2LVV5, SYR_SYNAS  ;  Q8KPU9, SYR_SYNE7  ;  Q2JRC3, SYR_SYNJA  ;
DR   Q2JK96, SYR_SYNJB  ;  B1XPX8, SYR_SYNP2  ;  Q5N643, SYR_SYNP6  ;
DR   A5GP97, SYR_SYNPW  ;  Q7U3V8, SYR_SYNPX  ;  A5GW85, SYR_SYNR3  ;
DR   Q0I6R7, SYR_SYNS3  ;  Q3AVY5, SYR_SYNS9  ;  Q3AGU9, SYR_SYNSC  ;
DR   Q0AU94, SYR_SYNWW  ;  Q55486, SYR_SYNY3  ;  C5BNG6, SYR_TERTT  ;
DR   Q9HLE7, SYR_THEAC  ;  Q8DKN4, SYR_THEEB  ;  Q47TB0, SYR_THEFY  ;
DR   Q9X0H8, SYR_THEMA  ;  A5IN82, SYR_THEP1  ;  C5ZZZ3, SYR_THESM  ;
DR   B1L826, SYR_THESQ  ;  Q72GE2, SYR_THET2  ;  Q5SM45, SYR_THET8  ;
DR   Q8R786, SYR_THETN  ;  Q31J79, SYR_THICR  ;  Q3SF80, SYR_THIDA  ;
DR   B8GU79, SYR_THISH  ;  Q73P28, SYR_TREDE  ;  O83803, SYR_TREPA  ;
DR   B2S469, SYR_TREPS  ;  Q10XL4, SYR_TRIEI  ;  Q83HT0, SYR_TROW8  ;
DR   Q83GE9, SYR_TROWT  ;  Q0W6L7, SYR_UNCMA  ;  B1AIR8, SYR_UREP2  ;
DR   Q9PQL3, SYR_UREPA  ;  A5CXW2, SYR_VESOH  ;  Q9KQC6, SYR_VIBCH  ;
DR   Q5E6L2, SYR_VIBF1  ;  B5FC42, SYR_VIBFM  ;  A7MT26, SYR_VIBHB  ;
DR   Q87RD6, SYR_VIBPA  ;  B7VI24, SYR_VIBSL  ;  Q8DFR1, SYR_VIBVU  ;
DR   Q7MMM3, SYR_VIBVY  ;  Q8D372, SYR_WIGBR  ;  Q73HY6, SYR_WOLPM  ;
DR   B3CNF3, SYR_WOLPP  ;  Q7MAK6, SYR_WOLSU  ;  Q5GT78, SYR_WOLTR  ;
DR   Q8PFR2, SYR_XANAC  ;  Q3BNA3, SYR_XANC5  ;  Q4UPN9, SYR_XANC8  ;
DR   B0RXM6, SYR_XANCB  ;  Q8P455, SYR_XANCP  ;  Q2P8B1, SYR_XANOM  ;
DR   B2SS22, SYR_XANOP  ;  Q5H5M2, SYR_XANOR  ;  A7IN73, SYR_XANP2  ;
DR   B2I6M4, SYR_XYLF2  ;  Q9PGZ9, SYR_XYLFA  ;  B0U1H9, SYR_XYLFM  ;
DR   Q87F22, SYR_XYLFT  ;  A1JRM9, SYR_YERE8  ;  A7FID8, SYR_YERP3  ;
DR   Q1C827, SYR_YERPA  ;  B2K312, SYR_YERPB  ;  Q8ZEV7, SYR_YERPE  ;
DR   A9QYY6, SYR_YERPG  ;  Q1CJH7, SYR_YERPN  ;  A4TJL3, SYR_YERPP  ;
DR   Q66AV1, SYR_YERPS  ;  B1JLM2, SYR_YERPY  ;
//
ID   6.1.1.20
DE   Phenylalanine--tRNA ligase.
AN   Phenylalanine translase.
AN   Phenylalanyl-tRNA synthetase.
CA   ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-
CA   tRNA(Phe).
PR   PROSITE; PDOC00363;
DR   Q6AZG6, SYFAA_XENLA;  Q7SYV0, SYFAB_XENLA;  B0C6I2, SYFA_ACAM1 ;
DR   A9NEU5, SYFA_ACHLI ;  A1TR35, SYFA_ACIAC ;  Q6F872, SYFA_ACIAD ;
DR   B0VV85, SYFA_ACIBS ;  B0V5Q6, SYFA_ACIBY ;  B9MHY2, SYFA_ACIET ;
DR   B7J7S6, SYFA_ACIF2 ;  B5EN53, SYFA_ACIF5 ;  A1W8I2, SYFA_ACISJ ;
DR   A3MZX4, SYFA_ACTP2 ;  B3H137, SYFA_ACTP7 ;  B0BUG7, SYFA_ACTPJ ;
DR   A6VP83, SYFA_ACTSZ ;  A0KKP5, SYFA_AERHH ;  Q9Y9I6, SYFA_AERPE ;
DR   A4SMA8, SYFA_AERS4 ;  B9J7G4, SYFA_AGRRK ;  Q8UIN5, SYFA_AGRT5 ;
DR   B9JYN0, SYFA_AGRVS ;  Q0VNG2, SYFA_ALCBS ;  B6EN08, SYFA_ALISL ;
DR   A6TNP8, SYFA_ALKMQ ;  A8MI78, SYFA_ALKOO ;  B4RS43, SYFA_ALTMD ;
DR   B3ERN3, SYFA_AMOA5 ;  Q5PBV2, SYFA_ANAMM ;  B9MRS9, SYFA_ANATD ;
DR   Q3MB99, SYFA_ANAVT ;  B7GGW8, SYFA_ANOFW ;  O67087, SYFA_AQUAE ;
DR   Q9T034, SYFA_ARATH ;  O28324, SYFA_ARCFU ;  Q5P7X9, SYFA_AROAE ;
DR   Q2NJZ3, SYFA_AYWBP ;  B6YQ38, SYFA_AZOPC ;  A1K4E5, SYFA_AZOSB ;
DR   C1DF46, SYFA_AZOVD ;  C3PAE9, SYFA_BACAA ;  C3L8T8, SYFA_BACAC ;
DR   Q81L30, SYFA_BACAN ;  B7JR67, SYFA_BACC0 ;  Q72ZI1, SYFA_BACC1 ;
DR   B7IJW0, SYFA_BACC2 ;  C1EU00, SYFA_BACC3 ;  B7HF77, SYFA_BACC4 ;
DR   B7HRK2, SYFA_BACC7 ;  A7GTL0, SYFA_BACCN ;  B9J063, SYFA_BACCQ ;
DR   Q817I6, SYFA_BACCR ;  Q633N4, SYFA_BACCZ ;  Q5LAS4, SYFA_BACFN ;
DR   Q64R71, SYFA_BACFR ;  Q9K895, SYFA_BACHD ;  Q6HCW7, SYFA_BACHK ;
DR   Q65GD2, SYFA_BACLD ;  A8FG17, SYFA_BACP2 ;  Q5WEJ5, SYFA_BACSK ;
DR   P17921, SYFA_BACSU ;  Q8A756, SYFA_BACTN ;  A6L2I3, SYFA_BACV8 ;
DR   A9VJM4, SYFA_BACWK ;  A1UUA8, SYFA_BARBK ;  Q6G5E3, SYFA_BARHE ;
DR   Q6G0Y4, SYFA_BARQU ;  A9ILQ3, SYFA_BART1 ;  Q6MMJ2, SYFA_BDEBA ;
DR   B2IGL6, SYFA_BEII9 ;  B8DU51, SYFA_BIFA0 ;  A1A1X6, SYFA_BIFAA ;
DR   Q8G5E7, SYFA_BIFLO ;  B7GTP9, SYFA_BIFLS ;  Q7VR67, SYFA_BLOFL ;
DR   Q492V1, SYFA_BLOPB ;  Q7WKR5, SYFA_BORBR ;  P94282, SYFA_BORBU ;
DR   Q7W7C7, SYFA_BORPA ;  Q7VVR4, SYFA_BORPE ;  Q89WI1, SYFA_BRAJA ;
DR   A5E8L7, SYFA_BRASB ;  A4YJN0, SYFA_BRASO ;  B2S9B8, SYFA_BRUA1 ;
DR   Q2YQV5, SYFA_BRUA2 ;  Q57AE0, SYFA_BRUAB ;  A9M9V4, SYFA_BRUC2 ;
DR   C0RG06, SYFA_BRUMB ;  Q8YE73, SYFA_BRUME ;  A5VT73, SYFA_BRUO2 ;
DR   B0CJX0, SYFA_BRUSI ;  Q8FXX5, SYFA_BRUSU ;  P57229, SYFA_BUCAI ;
DR   P59056, SYFA_BUCAP ;  P59504, SYFA_BUCBP ;  B4E7I9, SYFA_BURCJ ;
DR   A3MJU2, SYFA_BURM7 ;  Q62KI6, SYFA_BURMA ;  A3NUI8, SYFA_BURP0 ;
DR   Q3JT08, SYFA_BURP1 ;  B2SZF8, SYFA_BURPP ;  Q63TM6, SYFA_BURPS ;
DR   Q39H51, SYFA_BURS3 ;  Q2SVE2, SYFA_BURTA ;  A4JDU8, SYFA_BURVG ;
DR   A4XKJ8, SYFA_CALS8 ;  A8FLU6, SYFA_CAMJ8 ;  A7H3F0, SYFA_CAMJD ;
DR   Q9PP34, SYFA_CAMJE ;  A1VZN1, SYFA_CAMJJ ;  Q5HUR1, SYFA_CAMJR ;
DR   B9KD77, SYFA_CAMLR ;  Q3ABT4, SYFA_CARHZ ;  B8H307, SYFA_CAUCN ;
DR   Q9A9E4, SYFA_CAUCR ;  B0SXZ7, SYFA_CAUSK ;  B3PL12, SYFA_CELJU ;
DR   Q5ZJQ2, SYFA_CHICK ;  Q5L5A8, SYFA_CHLAB ;  Q3APW3, SYFA_CHLCH ;
DR   Q822B5, SYFA_CHLCV ;  Q255M0, SYFA_CHLFF ;  B3EEB7, SYFA_CHLL2 ;
DR   Q9PL83, SYFA_CHLMU ;  B3QRM0, SYFA_CHLP8 ;  B3EKG5, SYFA_CHLPB ;
DR   A1BJB6, SYFA_CHLPD ;  Q9Z6R6, SYFA_CHLPN ;  B3QUV1, SYFA_CHLT3 ;
DR   Q3KKK3, SYFA_CHLTA ;  Q8KAM6, SYFA_CHLTE ;  O84843, SYFA_CHLTR ;
DR   Q1QWK3, SYFA_CHRSD ;  Q7NYC2, SYFA_CHRVO ;  Q97GK9, SYFA_CLOAB ;
DR   A7FY80, SYFA_CLOB1 ;  C3KTJ3, SYFA_CLOB6 ;  A6LTR7, SYFA_CLOB8 ;
DR   B2V594, SYFA_CLOBA ;  B2TS55, SYFA_CLOBB ;  A5I6L1, SYFA_CLOBH ;
DR   C1FKM3, SYFA_CLOBJ ;  B1IML3, SYFA_CLOBK ;  A7GHZ8, SYFA_CLOBL ;
DR   B1L0T0, SYFA_CLOBM ;  A5N254, SYFA_CLOK5 ;  A0PZN8, SYFA_CLONN ;
DR   Q0TP72, SYFA_CLOP1 ;  Q8XJ75, SYFA_CLOPE ;  A9KHY1, SYFA_CLOPH ;
DR   Q0SRU1, SYFA_CLOPS ;  Q891T7, SYFA_CLOTE ;  A3DBX6, SYFA_CLOTH ;
DR   Q47ZS4, SYFA_COLP3 ;  Q6NHH2, SYFA_CORDI ;  Q8FTP1, SYFA_COREF ;
DR   Q8NQN7, SYFA_CORGL ;  Q4JW06, SYFA_CORJK ;  B6J7X7, SYFA_COXB1 ;
DR   B6IZG0, SYFA_COXB2 ;  A9KGB7, SYFA_COXBN ;  A9N8K1, SYFA_COXBR ;
DR   Q83C14, SYFA_COXBU ;  Q0KBY9, SYFA_CUPNH ;  Q472N4, SYFA_CUPPJ ;
DR   B3R4J5, SYFA_CUPTR ;  Q11Q26, SYFA_CYTH3 ;  Q1JPX3, SYFA_DANRE ;
DR   Q47CM8, SYFA_DECAR ;  Q3Z9I8, SYFA_DEHE1 ;  A5FS95, SYFA_DEHSB ;
DR   Q3ZZD3, SYFA_DEHSC ;  C1CYT5, SYFA_DEIDV ;  Q1J1V8, SYFA_DEIGD ;
DR   Q9RRX8, SYFA_DEIRA ;  A9C3D0, SYFA_DELAS ;  B8FFU3, SYFA_DESAA ;
DR   B1I4I5, SYFA_DESAP ;  B8J4E0, SYFA_DESDA ;  Q30Y15, SYFA_DESDG ;
DR   B8G0L8, SYFA_DESHD ;  Q251I2, SYFA_DESHY ;  A8ZZ70, SYFA_DESOH ;
DR   Q6ANC1, SYFA_DESPS ;  A4J4Z4, SYFA_DESRM ;  Q728R9, SYFA_DESVH ;
DR   B8DPM8, SYFA_DESVM ;  A1VBB8, SYFA_DESVV ;  Q54KS8, SYFA_DICDI ;
DR   B5YER5, SYFA_DICT6 ;  B8E0D9, SYFA_DICTD ;  A8LLH4, SYFA_DINSH ;
DR   Q9W3J5, SYFA_DROME ;  A7ZMI2, SYFA_ECO24 ;  B7US97, SYFA_ECO27 ;
DR   B7MAS5, SYFA_ECO45 ;  B7L6I7, SYFA_ECO55 ;  P67037, SYFA_ECO57 ;
DR   B5YQ02, SYFA_ECO5E ;  B7NT62, SYFA_ECO7I ;  B7MVJ3, SYFA_ECO81 ;
DR   B7M1C3, SYFA_ECO8A ;  C4ZYH6, SYFA_ECOBW ;  B1XG21, SYFA_ECODH ;
DR   A8A0Q6, SYFA_ECOHS ;  Q0THB4, SYFA_ECOL5 ;  P67036, SYFA_ECOL6 ;
DR   B1IPL3, SYFA_ECOLC ;  P08312, SYFA_ECOLI ;  B7N552, SYFA_ECOLU ;
DR   B6I8Q7, SYFA_ECOSE ;  B1LE16, SYFA_ECOSM ;  C5B850, SYFA_EDWI9 ;
DR   Q3YSX1, SYFA_EHRCJ ;  Q2GHR3, SYFA_EHRCR ;  Q5FH45, SYFA_EHRRG ;
DR   Q5HC40, SYFA_EHRRW ;  Q8SRG9, SYFA_ENCCU ;  A4W9M7, SYFA_ENT38 ;
DR   B7XI98, SYFA_ENTBH ;  Q836J6, SYFA_ENTFA ;  A7MNY9, SYFA_ENTS8 ;
DR   Q6D4H2, SYFA_ERWCT ;  B2VEL4, SYFA_ERWT9 ;  Q2N631, SYFA_ERYLH ;
DR   B7LQ75, SYFA_ESCF3 ;  C4ZBJ4, SYFA_EUBR3 ;  B1YJZ8, SYFA_EXIS2 ;
DR   C4L450, SYFA_EXISA ;  A7HLU6, SYFA_FERNB ;  A5FLW1, SYFA_FLAJ1 ;
DR   A6GVW9, SYFA_FLAPJ ;  B0U0C4, SYFA_FRAP2 ;  Q14HK5, SYFA_FRAT1 ;
DR   A7NCN7, SYFA_FRATF ;  Q2A322, SYFA_FRATH ;  B2SGL8, SYFA_FRATM ;
DR   A0Q6A6, SYFA_FRATN ;  Q0BLJ8, SYFA_FRATO ;  Q5NG53, SYFA_FRATT ;
DR   A4IXV3, SYFA_FRATW ;  Q8RHB4, SYFA_FUSNN ;  C1A492, SYFA_GEMAT ;
DR   B5EBY3, SYFA_GEOBB ;  Q5KWE4, SYFA_GEOKA ;  B3E1T9, SYFA_GEOLS ;
DR   Q39VS5, SYFA_GEOMG ;  B9M520, SYFA_GEOSF ;  Q74D00, SYFA_GEOSL ;
DR   C6DYJ1, SYFA_GEOSM ;  C5D627, SYFA_GEOSW ;  A4IRM4, SYFA_GEOTN ;
DR   A5G4T3, SYFA_GEOUR ;  Q7NGP0, SYFA_GLOVI ;  A9H167, SYFA_GLUDA ;
DR   Q5FUA1, SYFA_GLUOX ;  A0M6W9, SYFA_GRAFK ;  Q7VLG2, SYFA_HAEDU ;
DR   Q4QKM4, SYFA_HAEI8 ;  A5UCB0, SYFA_HAEIE ;  P43819, SYFA_HAEIN ;
DR   B8F4T5, SYFA_HAEPS ;  Q0I3K7, SYFA_HAES1 ;  B0UU57, SYFA_HAES2 ;
DR   Q2SDJ6, SYFA_HAHCH ;  B0R806, SYFA_HALS3 ;  Q9HMK4, SYFA_HALSA ;
DR   C4K781, SYFA_HAMD5 ;  Q17YI4, SYFA_HELAH ;  Q7VK64, SYFA_HELHP ;
DR   B0TEV9, SYFA_HELMI ;  B6JMP1, SYFA_HELP2 ;  B5Z848, SYFA_HELPG ;
DR   Q1CSL6, SYFA_HELPH ;  Q9ZKF9, SYFA_HELPJ ;  B2UUF7, SYFA_HELPS ;
DR   P56146, SYFA_HELPY ;  A9B8B9, SYFA_HERA2 ;  A4G615, SYFA_HERAR ;
DR   Q9Y285, SYFA_HUMAN ;  Q0C530, SYFA_HYPNA ;  Q5QXL7, SYFA_IDILO ;
DR   A6SY34, SYFA_JANMA ;  Q28V93, SYFA_JANSC ;  B5XQD0, SYFA_KLEP3 ;
DR   A6TAI3, SYFA_KLEP7 ;  Q5FIY6, SYFA_LACAC ;  Q03RM9, SYFA_LACBA ;
DR   Q038C7, SYFA_LACC3 ;  B3WF19, SYFA_LACCB ;  Q1G9C7, SYFA_LACDA ;
DR   Q041W8, SYFA_LACGA ;  A8YWB7, SYFA_LACH4 ;  Q74IE1, SYFA_LACJO ;
DR   Q9CEB4, SYFA_LACLA ;  A2RN75, SYFA_LACLM ;  Q02WL3, SYFA_LACLS ;
DR   Q88WR3, SYFA_LACPL ;  A5VKV1, SYFA_LACRD ;  B2G885, SYFA_LACRJ ;
DR   Q1WTY9, SYFA_LACS1 ;  Q38VV3, SYFA_LACSS ;  C1DDA2, SYFA_LARHH ;
DR   Q1MRV5, SYFA_LAWIP ;  Q5X1H7, SYFA_LEGPA ;  A5IAL3, SYFA_LEGPC ;
DR   Q5ZS08, SYFA_LEGPH ;  Q5WT86, SYFA_LEGPL ;  Q6AGD7, SYFA_LEIXX ;
DR   B0SBK8, SYFA_LEPBA ;  Q04P74, SYFA_LEPBJ ;  Q056G0, SYFA_LEPBL ;
DR   B0SJ52, SYFA_LEPBP ;  B1XYZ7, SYFA_LEPCP ;  Q72M80, SYFA_LEPIC ;
DR   Q8EYR3, SYFA_LEPIN ;  B1MXE0, SYFA_LEUCK ;  Q92CI7, SYFA_LISIN ;
DR   C1L2C6, SYFA_LISMC ;  Q720K8, SYFA_LISMF ;  B8DI11, SYFA_LISMH ;
DR   Q8Y7Q2, SYFA_LISMO ;  A0AHW2, SYFA_LISW6 ;  B1HWA2, SYFA_LYSSC ;
DR   B9E766, SYFA_MACCJ ;  A0L4K0, SYFA_MAGSM ;  Q65TL2, SYFA_MANSM ;
DR   A1U2B9, SYFA_MARAV ;  A6VYH7, SYFA_MARMS ;  Q6F165, SYFA_MESFL ;
DR   Q11KJ9, SYFA_MESSB ;  Q8TUA2, SYFA_METAC ;  Q46CQ6, SYFA_METBF ;
DR   Q60AZ0, SYFA_METCA ;  Q1GZS1, SYFA_METFK ;  Q2FLL0, SYFA_METHJ ;
DR   Q57911, SYFA_METJA ;  Q8TYM5, SYFA_METKA ;  A2ST81, SYFA_METLZ ;
DR   A4FW27, SYFA_METM5 ;  A6VH81, SYFA_METM7 ;  Q8PWV6, SYFA_METMA ;
DR   A3CT76, SYFA_METMJ ;  Q6LX56, SYFA_METMP ;  B8IP76, SYFA_METNO ;
DR   A2SH03, SYFA_METPP ;  B1M6P5, SYFA_METRJ ;  B0UPJ5, SYFA_METS4 ;
DR   A4YIL1, SYFA_METS5 ;  B8ESQ6, SYFA_METSB ;  O26837, SYFA_METTH ;
DR   A6UQD9, SYFA_METVS ;  Q2RHN7, SYFA_MOOTA ;  Q8C0C7, SYFA_MOUSE ;
DR   A0QHB6, SYFA_MYCA1 ;  Q7VEV4, SYFA_MYCBO ;  A1KJ66, SYFA_MYCBP ;
DR   C1ANS2, SYFA_MYCBT ;  Q2SSA0, SYFA_MYCCT ;  Q7NBB8, SYFA_MYCGA ;
DR   P47436, SYFA_MYCGE ;  A4T9V2, SYFA_MYCGI ;  Q9CC17, SYFA_MYCLE ;
DR   Q6MT17, SYFA_MYCMS ;  Q740J1, SYFA_MYCPA ;  Q8EUJ8, SYFA_MYCPE ;
DR   P75564, SYFA_MYCPN ;  A5U306, SYFA_MYCTA ;  P94984, SYFA_MYCTU ;
DR   A1TAB5, SYFA_MYCVP ;  Q1D6E0, SYFA_MYXXD ;  B2A5N5, SYFA_NATTJ ;
DR   Q5F9U0, SYFA_NEIG1 ;  Q9JR76, SYFA_NEIMA ;  Q9K092, SYFA_NEIMB ;
DR   Q82VV5, SYFA_NITEU ;  Q1QS22, SYFA_NITHX ;  Q2YBS2, SYFA_NITMU ;
DR   Q3JBZ8, SYFA_NITOC ;  Q3SWK7, SYFA_NITWN ;  Q5YYH7, SYFA_NOCFA ;
DR   C4V6K5, SYFA_NOSCE ;  B2IUA1, SYFA_NOSP7 ;  Q8YMT4, SYFA_NOSS1 ;
DR   Q2GAI8, SYFA_NOVAD ;  Q8EPH4, SYFA_OCEIH ;  A6WX16, SYFA_OCHA4 ;
DR   Q04FD8, SYFA_OENOB ;  B6JCK5, SYFA_OLICO ;  Q6YPX9, SYFA_ONYPE ;
DR   A6LA92, SYFA_PARD8 ;  A1B4B8, SYFA_PARDP ;  Q6MDC0, SYFA_PARUW ;
DR   P57860, SYFA_PASMU ;  C6DFZ0, SYFA_PECCP ;  Q3A4N9, SYFA_PELCD ;
DR   Q3B6M2, SYFA_PELLD ;  B4SB89, SYFA_PELPB ;  A1ARE1, SYFA_PELPD ;
DR   A5D0U1, SYFA_PELTS ;  Q4FNH5, SYFA_PELUB ;  C0QT55, SYFA_PERMH ;
DR   A9BFH2, SYFA_PETMO ;  B4R9C6, SYFA_PHEZH ;  Q7N3Q0, SYFA_PHOLL ;
DR   Q6LQ72, SYFA_PHOPR ;  B1VA93, SYFA_PHYAS ;  Q5RFA2, SYFA_PONAB ;
DR   B2RLI5, SYFA_PORG3 ;  Q7MU04, SYFA_PORGI ;  B4S3C8, SYFA_PROA2 ;
DR   Q6A7V5, SYFA_PROAC ;  Q319M1, SYFA_PROM9 ;  Q7VAV9, SYFA_PROMA ;
DR   B4ETL0, SYFA_PROMH ;  Q7TV42, SYFA_PROMM ;  Q7V0I7, SYFA_PROMP ;
DR   Q46JK1, SYFA_PROMT ;  A4SCK0, SYFA_PROVI ;  Q48JR9, SYFA_PSE14 ;
DR   Q15SX7, SYFA_PSEA6 ;  A6V489, SYFA_PSEA7 ;  B7V310, SYFA_PSEA8 ;
DR   Q02NN7, SYFA_PSEAB ;  Q9I0A3, SYFA_PSEAE ;  Q1IC11, SYFA_PSEE4 ;
DR   Q4KEW0, SYFA_PSEF5 ;  C3JZN3, SYFA_PSEFS ;  A4XTS5, SYFA_PSEMY ;
DR   A5W5D7, SYFA_PSEP1 ;  Q3KEX8, SYFA_PSEPF ;  B0KKR4, SYFA_PSEPG ;
DR   Q88K23, SYFA_PSEPK ;  B1J6U8, SYFA_PSEPW ;  Q883H8, SYFA_PSESM ;
DR   Q4ZUG3, SYFA_PSEU2 ;  Q4FQ65, SYFA_PSYA2 ;  Q9UYX3, SYFA_PYRAB ;
DR   Q8ZX61, SYFA_PYRAE ;  A4WHY5, SYFA_PYRAR ;  A3MUA4, SYFA_PYRCJ ;
DR   Q8U261, SYFA_PYRFU ;  O58391, SYFA_PYRHO ;  Q76KA8, SYFA_PYRKO ;
DR   Q1LP76, SYFA_RALME ;  B2UGJ4, SYFA_RALPJ ;  Q8XZ25, SYFA_RALSO ;
DR   Q505J8, SYFA_RAT   ;  B3PYE2, SYFA_RHIE6 ;  Q2KDK0, SYFA_RHIEC ;
DR   Q1MMP3, SYFA_RHIL3 ;  Q98CP9, SYFA_RHILO ;  B5ZXS0, SYFA_RHILW ;
DR   Q92ST0, SYFA_RHIME ;  C3MCQ0, SYFA_RHISN ;  Q7UP75, SYFA_RHOBA ;
DR   B6IPK0, SYFA_RHOCS ;  Q21YS9, SYFA_RHOFD ;  Q6NDR7, SYFA_RHOPA ;
DR   Q21C64, SYFA_RHOPB ;  Q13ET5, SYFA_RHOPS ;  B3Q5X1, SYFA_RHOPT ;
DR   Q2RNH8, SYFA_RHORT ;  A3PGQ9, SYFA_RHOS1 ;  Q3J5M4, SYFA_RHOS4 ;
DR   B9KLE0, SYFA_RHOSK ;  C3PNE3, SYFA_RICAE ;  A8GND9, SYFA_RICAH ;
DR   A8GWH2, SYFA_RICB8 ;  Q1RIS9, SYFA_RICBR ;  A8EZ06, SYFA_RICCK ;
DR   Q92I39, SYFA_RICCN ;  Q4ULS5, SYFA_RICFE ;  Q9ZDB5, SYFA_RICPR ;
DR   C4K2A1, SYFA_RICPU ;  A8GS12, SYFA_RICRS ;  Q68WW2, SYFA_RICTY ;
DR   A7NJ67, SYFA_ROSCS ;  Q16BG6, SYFA_ROSDO ;  A5US42, SYFA_ROSS1 ;
DR   A1AWT1, SYFA_RUTMC ;  Q21KD6, SYFA_SACD2 ;  B5F7F8, SYFA_SALA4 ;
DR   Q57PU9, SYFA_SALCH ;  B5FJA4, SYFA_SALDC ;  B5QVW4, SYFA_SALEP ;
DR   B5RAW9, SYFA_SALG2 ;  B4TGH5, SYFA_SALHS ;  B4T4N2, SYFA_SALNS ;
DR   Q5PH92, SYFA_SALPA ;  A9N238, SYFA_SALPB ;  C0Q642, SYFA_SALPC ;
DR   B5BA38, SYFA_SALPK ;  Q2RYT4, SYFA_SALRD ;  B4TUF4, SYFA_SALSV ;
DR   P67039, SYFA_SALTI ;  P67038, SYFA_SALTY ;  O42870, SYFA_SCHPO ;
DR   A8GDQ9, SYFA_SERP5 ;  A1S702, SYFA_SHEAM ;  B8E7F5, SYFA_SHEB2 ;
DR   A6WMK4, SYFA_SHEB8 ;  Q12NU0, SYFA_SHEDO ;  Q083K7, SYFA_SHEFN ;
DR   Q8EFA0, SYFA_SHEON ;  A4Y6G8, SYFA_SHEPC ;  A8FWI2, SYFA_SHESH ;
DR   Q0HUP8, SYFA_SHESR ;  A1RK14, SYFA_SHESW ;  B1KRE3, SYFA_SHEWM ;
DR   B2U392, SYFA_SHIB3 ;  Q321K6, SYFA_SHIBS ;  Q32FI5, SYFA_SHIDS ;
DR   Q0T4S4, SYFA_SHIF8 ;  Q83L37, SYFA_SHIFL ;  Q3Z262, SYFA_SHISS ;
DR   Q5LMG9, SYFA_SILPO ;  Q1GDM3, SYFA_SILST ;  A6UF74, SYFA_SINMW ;
DR   Q2NT28, SYFA_SODGM ;  A9GN91, SYFA_SORC5 ;  A5V922, SYFA_SPHWW ;
DR   A7X160, SYFA_STAA1 ;  A6U0V5, SYFA_STAA2 ;  Q2FHU3, SYFA_STAA3 ;
DR   Q2FZD9, SYFA_STAA8 ;  A5IS24, SYFA_STAA9 ;  Q2YX87, SYFA_STAAB ;
DR   Q5HGU6, SYFA_STAAC ;  A6QG39, SYFA_STAAE ;  P68847, SYFA_STAAM ;
DR   P68848, SYFA_STAAN ;  Q6GHU7, SYFA_STAAR ;  Q6GA76, SYFA_STAAS ;
DR   A8Z1R9, SYFA_STAAT ;  P68849, SYFA_STAAU ;  P68850, SYFA_STAAW ;
DR   B9DPU8, SYFA_STACT ;  Q5HQ36, SYFA_STAEQ ;  Q8CSY9, SYFA_STAES ;
DR   Q4L5E3, SYFA_STAHJ ;  Q49WQ5, SYFA_STAS1 ;  Q3K1I9, SYFA_STRA1 ;
DR   Q8E5U3, SYFA_STRA3 ;  Q8E066, SYFA_STRA5 ;  Q828C7, SYFA_STRAW ;
DR   O88055, SYFA_STRCO ;  C0M7G8, SYFA_STRE4 ;  B4U2E8, SYFA_STREM ;
DR   B4SQH0, SYFA_STRM5 ;  B2FN75, SYFA_STRMK ;  Q8CWX1, SYFA_STRMU ;
DR   Q9A0I1, SYFA_STRP1 ;  Q04LU1, SYFA_STRP2 ;  P0DG50, SYFA_STRP3 ;
DR   Q5XCX4, SYFA_STRP6 ;  C1C5V0, SYFA_STRP7 ;  Q8P1K1, SYFA_STRP8 ;
DR   B1IAA1, SYFA_STRPI ;  Q97S36, SYFA_STRPN ;  P0DG51, SYFA_STRPQ ;
DR   B5XKQ6, SYFA_STRPZ ;  Q8DQT8, SYFA_STRR6 ;  C0MH11, SYFA_STRS7 ;
DR   Q5LZ70, SYFA_STRT1 ;  Q5M3S5, SYFA_STRT2 ;  Q03K19, SYFA_STRTD ;
DR   B9DRU2, SYFA_STRU0 ;  C1CCV6, SYFA_STRZJ ;  Q4J8P9, SYFA_SULAC ;
DR   Q30S84, SYFA_SULDN ;  A8Z6A5, SYFA_SULMW ;  A6Q7P7, SYFA_SULNB ;
DR   P95961, SYFA_SULSO ;  B2V6V0, SYFA_SULSY ;  Q971D7, SYFA_SULTO ;
DR   Q67QF3, SYFA_SYMTH ;  Q2LR28, SYFA_SYNAS ;  A0LFC6, SYFA_SYNFM ;
DR   Q7TTU6, SYFA_SYNPX ;  Q0AY00, SYFA_SYNWW ;  Q55187, SYFA_SYNY3 ;
DR   C5BSQ6, SYFA_TERTT ;  P57693, SYFA_THEAC ;  Q8DL09, SYFA_THEEB ;
DR   Q47N75, SYFA_THEFY ;  C5A5Y9, SYFA_THEGJ ;  Q9WZS8, SYFA_THEMA ;
DR   B9KAE8, SYFA_THENN ;  B6YTJ4, SYFA_THEON ;  A5IIW2, SYFA_THEP1 ;
DR   C6A236, SYFA_THESM ;  B1LCK9, SYFA_THESQ ;  Q72HA1, SYFA_THET2 ;
DR   Q5SGX2, SYFA_THET8 ;  P27001, SYFA_THETH ;  Q8R9C6, SYFA_THETN ;
DR   Q979U4, SYFA_THEVO ;  Q31F18, SYFA_THICR ;  Q3SK30, SYFA_THIDA ;
DR   B8GRI4, SYFA_THISH ;  C4LFG9, SYFA_TOLAT ;  O83938, SYFA_TREPA ;
DR   B2S4L0, SYFA_TREPS ;  Q83HH3, SYFA_TROW8 ;  Q83GS9, SYFA_TROWT ;
DR   Q0W0X9, SYFA_UNCMA ;  B1AJ99, SYFA_UREP2 ;  Q9PQ32, SYFA_UREPA ;
DR   B5ZBV3, SYFA_UREU1 ;  C5CUU6, SYFA_VARPS ;  A1WMG9, SYFA_VEREI ;
DR   A5F1W4, SYFA_VIBC3 ;  Q9KSN7, SYFA_VIBCH ;  C3LLR5, SYFA_VIBCM ;
DR   Q5E5G6, SYFA_VIBF1 ;  B5FDX4, SYFA_VIBFM ;  A7MVJ5, SYFA_VIBHB ;
DR   Q87Q60, SYFA_VIBPA ;  B7VPK0, SYFA_VIBSL ;  Q8DA40, SYFA_VIBVU ;
DR   Q7MK39, SYFA_VIBVY ;  Q8D3B6, SYFA_WIGBR ;  Q73IM5, SYFA_WOLPM ;
DR   B3CMZ6, SYFA_WOLPP ;  Q7M8Y9, SYFA_WOLSU ;  Q5GTJ5, SYFA_WOLTR ;
DR   C0R5D1, SYFA_WOLWR ;  Q8PJE4, SYFA_XANAC ;  Q3BRU1, SYFA_XANC5 ;
DR   Q4UW53, SYFA_XANC8 ;  B0RRH3, SYFA_XANCB ;  Q8P7Z5, SYFA_XANCP ;
DR   Q2P0Z9, SYFA_XANOM ;  B2SUL9, SYFA_XANOP ;  Q5GXY4, SYFA_XANOR ;
DR   B2I9P4, SYFA_XYLF2 ;  Q9PFD7, SYFA_XYLFA ;  B0U5D9, SYFA_XYLFM ;
DR   Q87AB5, SYFA_XYLFT ;  P15625, SYFA_YEAST ;  A1JML2, SYFA_YERE8 ;
DR   A7FHG5, SYFA_YERP3 ;  Q1C733, SYFA_YERPA ;  B2K664, SYFA_YERPB ;
DR   Q8ZDX0, SYFA_YERPE ;  A9R0A4, SYFA_YERPG ;  Q1CIG8, SYFA_YERPN ;
DR   A4TIL5, SYFA_YERPP ;  Q669Z5, SYFA_YERPS ;  B1JJ21, SYFA_YERPY ;
DR   Q5NMC2, SYFA_ZYMMO ;  Q6F873, SYFB_ACIAD ;  Q9Y9I3, SYFB_AERPE ;
DR   Q8UIN4, SYFB_AGRT5 ;  Q2IJB3, SYFB_ANADE ;  Q5PA83, SYFB_ANAMM ;
DR   Q3MAZ7, SYFB_ANAVT ;  O67620, SYFB_AQUAE ;  Q9SGE9, SYFB_ARATH ;
DR   O28848, SYFB_ARCFU ;  Q5P7Y0, SYFB_AROAE ;  Q2NJZ2, SYFB_AYWBP ;
DR   Q81L31, SYFB_BACAN ;  Q72ZI2, SYFB_BACC1 ;  Q817I7, SYFB_BACCR ;
DR   Q633N5, SYFB_BACCZ ;  Q5LC76, SYFB_BACFN ;  Q64T65, SYFB_BACFR ;
DR   Q9K896, SYFB_BACHD ;  Q6HCW8, SYFB_BACHK ;  Q65GD3, SYFB_BACLD ;
DR   Q5WEJ6, SYFB_BACSK ;  P17922, SYFB_BACSU ;  Q8AA39, SYFB_BACTN ;
DR   Q6G5I2, SYFB_BARHE ;  Q6G0Y3, SYFB_BARQU ;  Q6MMJ1, SYFB_BDEBA ;
DR   Q8G5E8, SYFB_BIFLO ;  Q7VR66, SYFB_BLOFL ;  Q492V0, SYFB_BLOPB ;
DR   Q0SMZ4, SYFB_BORAP ;  Q7WKR4, SYFB_BORBR ;  P94283, SYFB_BORBU ;
DR   B7J278, SYFB_BORBZ ;  B5RM71, SYFB_BORDL ;  Q661A7, SYFB_BORGA ;
DR   B2S0L6, SYFB_BORHD ;  Q7W7C6, SYFB_BORPA ;  Q7VVR5, SYFB_BORPE ;
DR   B5RPL7, SYFB_BORRA ;  A1QZU9, SYFB_BORT9 ;  Q89WI2, SYFB_BRAJA ;
DR   Q2YQV4, SYFB_BRUA2 ;  Q57AD9, SYFB_BRUAB ;  Q8YE74, SYFB_BRUME ;
DR   Q8FXX4, SYFB_BRUSU ;  P57230, SYFB_BUCAI ;  P59057, SYFB_BUCAP ;
DR   P59505, SYFB_BUCBP ;  Q62KI7, SYFB_BURMA ;  Q3JT07, SYFB_BURP1 ;
DR   Q63TM7, SYFB_BURPS ;  Q39H50, SYFB_BURS3 ;  Q2SVE3, SYFB_BURTA ;
DR   Q19713, SYFB_CAEEL ;  Q9PP35, SYFB_CAMJE ;  Q5HUR2, SYFB_CAMJR ;
DR   O13432, SYFB_CANAL ;  Q3ABT5, SYFB_CARHZ ;  Q9A9E5, SYFB_CAUCR ;
DR   Q5L6W7, SYFB_CHLAB ;  Q3AQC6, SYFB_CHLCH ;  Q824J8, SYFB_CHLCV ;
DR   Q9PJR8, SYFB_CHLMU ;  Q9Z7W0, SYFB_CHLPN ;  Q3KLM3, SYFB_CHLTA ;
DR   Q8KEF9, SYFB_CHLTE ;  O84481, SYFB_CHLTR ;  Q7NYC1, SYFB_CHRVO ;
DR   Q97GL0, SYFB_CLOAB ;  Q8XJ76, SYFB_CLOPE ;  Q891T8, SYFB_CLOTE ;
DR   Q47ZS5, SYFB_COLP3 ;  Q6NHH1, SYFB_CORDI ;  Q8FTP0, SYFB_COREF ;
DR   Q8NQN6, SYFB_CORGL ;  Q4JW05, SYFB_CORJK ;  Q83C15, SYFB_COXBU ;
DR   Q472N3, SYFB_CUPPJ ;  Q47CM9, SYFB_DECAR ;  Q3Z9I7, SYFB_DEHE1 ;
DR   Q3ZZD2, SYFB_DEHSC ;  Q9RRX5, SYFB_DEIRA ;  Q30Y16, SYFB_DESDG ;
DR   Q6ANC2, SYFB_DESPS ;  Q728S0, SYFB_DESVH ;  P37984, SYFB_DICD3 ;
DR   Q550D2, SYFB_DICDI ;  Q9VCA5, SYFB_DROME ;  Q8XE32, SYFB_ECO57 ;
DR   P59664, SYFB_ECOL6 ;  P07395, SYFB_ECOLI ;  Q3YRN4, SYFB_EHRCJ ;
DR   Q5FFS3, SYFB_EHRRG ;  Q5HAU7, SYFB_EHRRW ;  Q8SS40, SYFB_ENCCU ;
DR   A9CS50, SYFB_ENTBH ;  Q836J5, SYFB_ENTFA ;  Q6D4H3, SYFB_ERWCT ;
DR   Q5NG54, SYFB_FRATT ;  Q8RHB5, SYFB_FUSNN ;  Q5KWE5, SYFB_GEOKA ;
DR   Q39VS4, SYFB_GEOMG ;  Q74CZ9, SYFB_GEOSL ;  Q7NCQ2, SYFB_GLOVI ;
DR   Q5FUA2, SYFB_GLUOX ;  Q6B8Z8, SYFB_GRATL ;  Q7VLG3, SYFB_HAEDU ;
DR   Q4QKM3, SYFB_HAEI8 ;  P43820, SYFB_HAEIN ;  Q2SDJ7, SYFB_HAHCH ;
DR   B9LU47, SYFB_HALLT ;  Q5UYF3, SYFB_HALMA ;  B0R807, SYFB_HALS3 ;
DR   Q9HMK3, SYFB_HALSA ;  Q7VK65, SYFB_HELHP ;  Q9ZKF8, SYFB_HELPJ ;
DR   P56145, SYFB_HELPY ;  Q9NSD9, SYFB_HUMAN ;  Q5QXL8, SYFB_IDILO ;
DR   B1L7C0, SYFB_KORCO ;  Q5FIY7, SYFB_LACAC ;  Q74IE2, SYFB_LACJO ;
DR   Q9CEB5, SYFB_LACLA ;  Q88WR2, SYFB_LACPL ;  Q38VV4, SYFB_LACSS ;
DR   Q5X1H8, SYFB_LEGPA ;  Q5ZS09, SYFB_LEGPH ;  Q5WT87, SYFB_LEGPL ;
DR   Q6AGD6, SYFB_LEIXX ;  B0SAR6, SYFB_LEPBA ;  Q04VV0, SYFB_LEPBJ ;
DR   Q04XL9, SYFB_LEPBL ;  B0SJF2, SYFB_LEPBP ;  Q72MG8, SYFB_LEPIC ;
DR   Q8EZ26, SYFB_LEPIN ;  Q92CI6, SYFB_LISIN ;  Q720K7, SYFB_LISMF ;
DR   Q8Y7Q1, SYFB_LISMO ;  Q2VYZ1, SYFB_MAGSA ;  Q65TL3, SYFB_MANSM ;
DR   Q6F166, SYFB_MESFL ;  A6UWT1, SYFB_META3 ;  Q8TPF7, SYFB_METAC ;
DR   A7I615, SYFB_METB6 ;  Q468N7, SYFB_METBF ;  Q12YP2, SYFB_METBU ;
DR   Q60AY9, SYFB_METCA ;  Q2FLL1, SYFB_METHJ ;  Q58508, SYFB_METJA ;
DR   Q8TX56, SYFB_METKA ;  A2ST82, SYFB_METLZ ;  A4FWS3, SYFB_METM5 ;
DR   A9AA58, SYFB_METM6 ;  A6VGJ4, SYFB_METM7 ;  Q8PTA5, SYFB_METMA ;
DR   A3CT77, SYFB_METMJ ;  Q6LXU2, SYFB_METMP ;  B8GEX4, SYFB_METPE ;
DR   A4YIL0, SYFB_METS5 ;  Q2NGX9, SYFB_METST ;  O26864, SYFB_METTH ;
DR   A0B993, SYFB_METTP ;  A6UPQ4, SYFB_METVS ;  Q2RHN8, SYFB_MOOTA ;
DR   Q9WUA2, SYFB_MOUSE ;  Q7VEV3, SYFB_MYCBO ;  Q2SS99, SYFB_MYCCT ;
DR   Q7NBB7, SYFB_MYCGA ;  P47437, SYFB_MYCGE ;  Q601U6, SYFB_MYCH2 ;
DR   Q4A891, SYFB_MYCH7 ;  Q4AA64, SYFB_MYCHJ ;  Q9CC16, SYFB_MYCLE ;
DR   Q6KHC8, SYFB_MYCMO ;  Q6MT18, SYFB_MYCMS ;  Q740J0, SYFB_MYCPA ;
DR   Q8EUJ9, SYFB_MYCPE ;  P75563, SYFB_MYCPN ;  Q98QL4, SYFB_MYCPU ;
DR   Q4A6A2, SYFB_MYCS5 ;  P94985, SYFB_MYCTU ;  Q3ITU5, SYFB_NATPD ;
DR   Q5F9T6, SYFB_NEIG1 ;  Q9JVA0, SYFB_NEIMA ;  Q9K089, SYFB_NEIMB ;
DR   Q82VV6, SYFB_NITEU ;  Q2YBS1, SYFB_NITMU ;  Q3JBZ7, SYFB_NITOC ;
DR   Q3SWK8, SYFB_NITWN ;  Q5YYH6, SYFB_NOCFA ;  C4VA52, SYFB_NOSCE ;
DR   Q8YMH5, SYFB_NOSS1 ;  Q2GAI7, SYFB_NOVAD ;  Q8EPH5, SYFB_OCEIH ;
DR   Q6YPX7, SYFB_ONYPE ;  Q6MEA6, SYFB_PARUW ;  P57859, SYFB_PASMU ;
DR   Q3A4N8, SYFB_PELCD ;  Q3B4Z2, SYFB_PELLD ;  Q4FNH4, SYFB_PELUB ;
DR   A0T0H4, SYFB_PHATC ;  Q7N3Q1, SYFB_PHOLL ;  Q6LQ73, SYFB_PHOPR ;
DR   Q5R7F7, SYFB_PONAB ;  Q7MXR4, SYFB_PORGI ;  P51346, SYFB_PORPU ;
DR   Q1XDE1, SYFB_PORYE ;  Q6A7V6, SYFB_PROAC ;  Q31AV5, SYFB_PROM9 ;
DR   Q7VBX6, SYFB_PROMA ;  Q7V7K5, SYFB_PROMM ;  Q7V1J8, SYFB_PROMP ;
DR   Q46KZ8, SYFB_PROMT ;  Q48JR8, SYFB_PSE14 ;  Q9I0A4, SYFB_PSEAE ;
DR   Q4KEV9, SYFB_PSEF5 ;  Q3IIL2, SYFB_PSEHT ;  Q3KEX7, SYFB_PSEPF ;
DR   Q88K22, SYFB_PSEPK ;  Q883H7, SYFB_PSESM ;  Q4ZUG2, SYFB_PSEU2 ;
DR   Q4FQ66, SYFB_PSYA2 ;  Q9UYX2, SYFB_PYRAB ;  Q8ZWQ7, SYFB_PYRAE ;
DR   Q8U260, SYFB_PYRFU ;  O73984, SYFB_PYRHO ;  Q76KA7, SYFB_PYRKO ;
DR   Q8XZ24, SYFB_RALSO ;  Q98CQ1, SYFB_RHILO ;  Q92SS9, SYFB_RHIME ;
DR   Q7UP77, SYFB_RHOBA ;  Q6NDR9, SYFB_RHOPA ;  Q2RNH7, SYFB_RHORT ;
DR   Q3J5M6, SYFB_RHOS4 ;  Q1RIS8, SYFB_RICBR ;  Q92I38, SYFB_RICCN ;
DR   Q4ULS4, SYFB_RICFE ;  Q9ZDB4, SYFB_RICPR ;  Q68WW1, SYFB_RICTY ;
DR   Q57PU8, SYFB_SALCH ;  Q5PH85, SYFB_SALPA ;  Q2RYT3, SYFB_SALRD ;
DR   Q8Z6I4, SYFB_SALTI ;  P15434, SYFB_SALTY ;  O42849, SYFB_SCHPO ;
DR   Q8EF99, SYFB_SHEON ;  Q321K5, SYFB_SHIBS ;  Q32FI6, SYFB_SHIDS ;
DR   Q83L36, SYFB_SHIFL ;  Q3Z261, SYFB_SHISS ;  Q5LMS3, SYFB_SILPO ;
DR   Q2NT27, SYFB_SODGM ;  Q01SP7, SYFB_SOLUE ;  Q2FHU2, SYFB_STAA3 ;
DR   Q2YX86, SYFB_STAAB ;  Q5HGU5, SYFB_STAAC ;  P67040, SYFB_STAAM ;
DR   P67041, SYFB_STAAN ;  Q6GHU6, SYFB_STAAR ;  Q6GA75, SYFB_STAAS ;
DR   Q9AGR3, SYFB_STAAU ;  Q8NX60, SYFB_STAAW ;  Q5HQ35, SYFB_STAEQ ;
DR   Q8CSY8, SYFB_STAES ;  Q4L5E4, SYFB_STAHJ ;  Q49WQ6, SYFB_STAS1 ;
DR   Q3K1I7, SYFB_STRA1 ;  Q8E5U1, SYFB_STRA3 ;  Q8E064, SYFB_STRA5 ;
DR   Q828C6, SYFB_STRAW ;  O88054, SYFB_STRCO ;  Q8CWX2, SYFB_STRMU ;
DR   Q9A0I0, SYFB_STRP1 ;  P0DG52, SYFB_STRP3 ;  Q5XCX3, SYFB_STRP6 ;
DR   Q8P1K0, SYFB_STRP8 ;  Q48UC5, SYFB_STRPM ;  Q97S34, SYFB_STRPN ;
DR   P0DG53, SYFB_STRPQ ;  Q8DQT6, SYFB_STRR6 ;  Q5LZ72, SYFB_STRT1 ;
DR   Q5M3S7, SYFB_STRT2 ;  Q4J8Q0, SYFB_SULAC ;  Q30S83, SYFB_SULDN ;
DR   C3N028, SYFB_SULIA ;  C4KJ68, SYFB_SULIK ;  C3MJ88, SYFB_SULIL ;
DR   C3MYY0, SYFB_SULIM ;  C3NMS5, SYFB_SULIN ;  C3N8B1, SYFB_SULIY ;
DR   P95960, SYFB_SULSO ;  Q971D8, SYFB_SULTO ;  Q67QF2, SYFB_SYMTH ;
DR   Q2LR26, SYFB_SYNAS ;  P74764, SYFB_SYNE7 ;  Q2JXF6, SYFB_SYNJA ;
DR   Q2JHU3, SYFB_SYNJB ;  Q5N5G8, SYFB_SYNP6 ;  Q7U6V9, SYFB_SYNPX ;
DR   Q3AVJ1, SYFB_SYNS9 ;  Q3AJY9, SYFB_SYNSC ;  P74296, SYFB_SYNY3 ;
DR   P57694, SYFB_THEAC ;  Q8DL37, SYFB_THEEB ;  Q47N76, SYFB_THEFY ;
DR   C5A5Z0, SYFB_THEGJ ;  Q9WZS9, SYFB_THEMA ;  B6YTJ3, SYFB_THEON ;
DR   A1RYS1, SYFB_THEPD ;  C6A237, SYFB_THESM ;  Q72HA0, SYFB_THET2 ;
DR   Q5SGX1, SYFB_THET8 ;  P27002, SYFB_THETH ;  Q8R9C7, SYFB_THETN ;
DR   Q97B53, SYFB_THEVO ;  Q31F19, SYFB_THICR ;  Q3SK29, SYFB_THIDA ;
DR   O83059, SYFB_TREPA ;  B2S1W3, SYFB_TREPS ;  Q83HH4, SYFB_TROW8 ;
DR   Q83GS8, SYFB_TROWT ;  Q0W0X4, SYFB_UNCMA ;  Q9PQ33, SYFB_UREPA ;
DR   Q9KSN6, SYFB_VIBCH ;  Q5E5G5, SYFB_VIBF1 ;  Q87Q59, SYFB_VIBPA ;
DR   Q8DA39, SYFB_VIBVU ;  Q7MK40, SYFB_VIBVY ;  Q8D3B5, SYFB_WIGBR ;
DR   Q73HW5, SYFB_WOLPM ;  Q7M8Y8, SYFB_WOLSU ;  Q5GSH5, SYFB_WOLTR ;
DR   Q8PJE5, SYFB_XANAC ;  Q3BRU2, SYFB_XANC5 ;  Q4UW52, SYFB_XANC8 ;
DR   Q8P7Z6, SYFB_XANCP ;  Q2P100, SYFB_XANOM ;  Q5GXY5, SYFB_XANOR ;
DR   Q9PFD6, SYFB_XYLFA ;  Q87AB6, SYFB_XYLFT ;  P15624, SYFB_YEAST ;
DR   Q8ZDX1, SYFB_YERPE ;  Q669Z6, SYFB_YERPS ;  Q5NMC3, SYFB_ZYMMO ;
DR   Q94K73, SYFM_ARATH ;  Q86A68, SYFM_DICDI ;  O16129, SYFM_DROME ;
DR   O95363, SYFM_HUMAN ;  Q99M01, SYFM_MOUSE ;  Q6AYQ3, SYFM_RAT   ;
DR   O74952, SYFM_SCHPO ;  P08425, SYFM_YEAST ;
//
ID   6.1.1.21
DE   Histidine--tRNA ligase.
AN   Histidine translase.
AN   Histidyl-tRNA synthetase.
CA   ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His).
PR   PROSITE; PDOC00363;
DR   Q81N41, SYH1_BACAN ;  P62367, SYH1_BACC1 ;  Q81B71, SYH1_BACCR ;
DR   Q638Q6, SYH1_BACCZ ;  Q6HG86, SYH1_BACHK ;  Q5WHP4, SYH1_BACSK ;
DR   Q81LI6, SYH2_BACAN ;  P62370, SYH2_BACC1 ;  Q817X7, SYH2_BACCR ;
DR   Q634E2, SYH2_BACCZ ;  Q6HDC2, SYH2_BACHK ;  Q5WCR7, SYH2_BACSK ;
DR   Q6E6B4, SYHC_ANTLO ;  Q2KI84, SYHC_BOVIN ;  Q86AS6, SYHC_DICDI ;
DR   Q8SRR3, SYHC_ENCCU ;  P12081, SYHC_HUMAN ;  P07178, SYHC_MESAU ;
DR   Q61035, SYHC_MOUSE ;  C4V9J0, SYHC_NOSCE ;  Q5R4R2, SYHC_PONAB ;
DR   P70076, SYHC_TAKRU ;  A5D7V9, SYHM_BOVIN ;  Q55D12, SYHM_DICDI ;
DR   P49590, SYHM_HUMAN ;  Q99KK9, SYHM_MOUSE ;  Q5R5E5, SYHM_PONAB ;
DR   B0CDA0, SYH_ACAM1  ;  A9NGF8, SYH_ACHLI  ;  Q6FEM2, SYH_ACIAD  ;
DR   B7H068, SYH_ACIB3  ;  B7I5G8, SYH_ACIB5  ;  B2I3E6, SYH_ACIBC  ;
DR   Q1ISE2, SYH_ACIBL  ;  B0VKR7, SYH_ACIBS  ;  A3M212, SYH_ACIBT  ;
DR   B0V5G6, SYH_ACIBY  ;  A5FX98, SYH_ACICJ  ;  B9MFX7, SYH_ACIET  ;
DR   A1W578, SYH_ACISJ  ;  B3GY63, SYH_ACTP7  ;  A6VQX5, SYH_ACTSZ  ;
DR   A0KJ45, SYH_AERHH  ;  Q9YEB2, SYH_AERPE  ;  A4SP01, SYH_AERS4  ;
DR   B9J9Y1, SYH_AGRRK  ;  Q8UHK4, SYH_AGRT5  ;  Q0VNE1, SYH_ALCBS  ;
DR   Q0A986, SYH_ALHEH  ;  A8MGM7, SYH_ALKOO  ;  B4RV88, SYH_ALTMD  ;
DR   B8JBF6, SYH_ANAD2  ;  B9KHM7, SYH_ANAMF  ;  Q5PBP9, SYH_ANAMM  ;
DR   Q2GLK4, SYH_ANAPZ  ;  B4UEL3, SYH_ANASK  ;  B9MPF7, SYH_ANATD  ;
DR   Q3MAV8, SYH_ANAVT  ;  B7GFR0, SYH_ANOFW  ;  O66522, SYH_AQUAE  ;
DR   O28631, SYH_ARCFU  ;  Q5P7B4, SYH_AROAE  ;  Q2NIN2, SYH_AYWBP  ;
DR   B6YS23, SYH_AZOPC  ;  A1K3Z0, SYH_AZOSB  ;  C1DE56, SYH_AZOVD  ;
DR   A7Z751, SYH_BACA2  ;  A7GT85, SYH_BACCN  ;  Q5LAE0, SYH_BACFN  ;
DR   Q64QS2, SYH_BACFR  ;  Q9KDG2, SYH_BACHD  ;  Q65GR3, SYH_BACLD  ;
DR   O32039, SYH_BACSU  ;  Q8A6N7, SYH_BACTN  ;  A6KXA6, SYH_BACV8  ;
DR   A1UTY3, SYH_BARBK  ;  Q6G289, SYH_BARHE  ;  Q6FYU5, SYH_BARQU  ;
DR   P60913, SYH_BDEBA  ;  B8DU04, SYH_BIFA0  ;  Q8G864, SYH_BIFLO  ;
DR   B7GPS9, SYH_BIFLS  ;  Q7VRR8, SYH_BLOFL  ;  Q492E1, SYH_BLOPB  ;
DR   Q2KY92, SYH_BORA1  ;  Q0SP28, SYH_BORAP  ;  Q7WHN1, SYH_BORBR  ;
DR   O51160, SYH_BORBU  ;  B7J168, SYH_BORBZ  ;  Q662M6, SYH_BORGA  ;
DR   Q7W6P7, SYH_BORPA  ;  Q7VWL1, SYH_BORPE  ;  Q89DI2, SYH_BRAJA  ;
DR   B2SCY7, SYH_BRUA1  ;  Q2YIH9, SYH_BRUA2  ;  Q579Q8, SYH_BRUAB  ;
DR   A9MDU4, SYH_BRUC2  ;  C0RKC7, SYH_BRUMB  ;  Q8YB45, SYH_BRUME  ;
DR   A5VTT4, SYH_BRUO2  ;  A9WXP3, SYH_BRUSI  ;  Q8FX93, SYH_BRUSU  ;
DR   P57375, SYH_BUCAI  ;  Q8K9P3, SYH_BUCAP  ;  P59482, SYH_BUCBP  ;
DR   B1YR43, SYH_BURA4  ;  Q1BGX3, SYH_BURCA  ;  B1JT91, SYH_BURCC  ;
DR   A0K7T5, SYH_BURCH  ;  B4EAW8, SYH_BURCJ  ;  Q0BEW8, SYH_BURCM  ;
DR   A9AGZ7, SYH_BURM1  ;  A3MK74, SYH_BURM7  ;  A2S2A3, SYH_BURM9  ;
DR   Q62JW5, SYH_BURMA  ;  A1V4K0, SYH_BURMS  ;  A3NVX0, SYH_BURP0  ;
DR   Q3JRQ5, SYH_BURP1  ;  A3NA53, SYH_BURP6  ;  B2JIV0, SYH_BURP8  ;
DR   B2SXS9, SYH_BURPP  ;  Q63UT2, SYH_BURPS  ;  Q39FR0, SYH_BURS3  ;
DR   Q2SWE3, SYH_BURTA  ;  A4JEN9, SYH_BURVG  ;  Q13X29, SYH_BURXL  ;
DR   P34183, SYH_CAEEL  ;  A4XHB0, SYH_CALS8  ;  A7ZDK1, SYH_CAMC1  ;
DR   A0RPD3, SYH_CAMFF  ;  A7I1U5, SYH_CAMHC  ;  A8FLH8, SYH_CAMJ8  ;
DR   A7H477, SYH_CAMJD  ;  Q9PPF4, SYH_CAMJE  ;  A1VZB3, SYH_CAMJJ  ;
DR   Q5HV27, SYH_CAMJR  ;  B9KG88, SYH_CAMLR  ;  Q3AA16, SYH_CARHZ  ;
DR   Q9A2P3, SYH_CAUCR  ;  Q5L735, SYH_CHLAB  ;  Q3AQK2, SYH_CHLCH  ;
DR   Q824R3, SYH_CHLCV  ;  Q252T8, SYH_CHLFF  ;  B3EFA6, SYH_CHLL2  ;
DR   Q9PJJ9, SYH_CHLMU  ;  B3QQI7, SYH_CHLP8  ;  B3ELN3, SYH_CHLPB  ;
DR   A1BDE6, SYH_CHLPD  ;  Q9Z7P1, SYH_CHLPN  ;  B0B8B7, SYH_CHLT2  ;
DR   B3QS95, SYH_CHLT3  ;  Q3KLF4, SYH_CHLTA  ;  B0B9Z6, SYH_CHLTB  ;
DR   Q8KFT6, SYH_CHLTE  ;  O84547, SYH_CHLTR  ;  Q1QTK7, SYH_CHRSD  ;
DR   Q7NS89, SYH_CHRVO  ;  Q97FJ7, SYH_CLOAB  ;  A7FY04, SYH_CLOB1  ;
DR   C3KTB7, SYH_CLOB6  ;  A5I6D6, SYH_CLOBH  ;  C1FKE6, SYH_CLOBJ  ;
DR   B1IMD8, SYH_CLOBK  ;  A7GHS3, SYH_CLOBL  ;  B1L097, SYH_CLOBM  ;
DR   Q183H5, SYH_CLOD6  ;  B9E5P3, SYH_CLOK1  ;  A5N1Y9, SYH_CLOK5  ;
DR   A0PZW9, SYH_CLONN  ;  Q0TP27, SYH_CLOP1  ;  Q8XJ27, SYH_CLOPE  ;
DR   A9KIA5, SYH_CLOPH  ;  Q0SRP7, SYH_CLOPS  ;  Q892X7, SYH_CLOTE  ;
DR   A3DF35, SYH_CLOTH  ;  Q47WC1, SYH_COLP3  ;  P60914, SYH_CORDI  ;
DR   Q8FPL5, SYH_COREF  ;  Q8NQ07, SYH_CORGL  ;  Q4JVE8, SYH_CORJK  ;
DR   C4LIW5, SYH_CORK4  ;  B1VDK9, SYH_CORU7  ;  B6J7Q5, SYH_COXB1  ;
DR   B6IZN1, SYH_COXB2  ;  A9KFU6, SYH_COXBN  ;  A9NDV9, SYH_COXBR  ;
DR   Q83C80, SYH_COXBU  ;  Q0K963, SYH_CUPNH  ;  Q46ZI4, SYH_CUPPJ  ;
DR   B3R1K1, SYH_CUPTR  ;  B1WVZ0, SYH_CYAA5  ;  B8HMM0, SYH_CYAP4  ;
DR   B7KFP0, SYH_CYAP7  ;  B7K2B6, SYH_CYAP8  ;  Q11RN9, SYH_CYTH3  ;
DR   Q47BR7, SYH_DECAR  ;  Q3ZAI8, SYH_DEHE1  ;  A5FSR7, SYH_DEHSB  ;
DR   Q3ZWB6, SYH_DEHSC  ;  C1CV35, SYH_DEIDV  ;  Q1IZB5, SYH_DEIGD  ;
DR   Q9RUN5, SYH_DEIRA  ;  B8FKS7, SYH_DESAA  ;  C6BVJ9, SYH_DESAD  ;
DR   C0QFI0, SYH_DESAH  ;  B1I363, SYH_DESAP  ;  Q317R4, SYH_DESDG  ;
DR   B8FQR7, SYH_DESHD  ;  Q24US1, SYH_DESHY  ;  C4XT36, SYH_DESMR  ;
DR   A8ZUR6, SYH_DESOH  ;  Q6AQS3, SYH_DESPS  ;  A4J2J1, SYH_DESRM  ;
DR   P62379, SYH_DESVH  ;  A1V9B1, SYH_DESVV  ;  B5YDT1, SYH_DICT6  ;
DR   B8E1C1, SYH_DICTD  ;  A8LKA5, SYH_DINSH  ;  A7ZPV7, SYH_ECO24  ;
DR   B7UGW0, SYH_ECO27  ;  B7MHZ9, SYH_ECO45  ;  B7LCQ4, SYH_ECO55  ;
DR   P60908, SYH_ECO57  ;  B5Z0Y3, SYH_ECO5E  ;  B7NRG4, SYH_ECO7I  ;
DR   B7MYE9, SYH_ECO81  ;  B7M7L8, SYH_ECO8A  ;  C4ZX89, SYH_ECOBW  ;
DR   B1XAY9, SYH_ECODH  ;  A8A320, SYH_ECOHS  ;  A1AE52, SYH_ECOK1  ;
DR   Q0TEX1, SYH_ECOL5  ;  P60907, SYH_ECOL6  ;  B1IWE7, SYH_ECOLC  ;
DR   P60906, SYH_ECOLI  ;  B7N6A2, SYH_ECOLU  ;  B6I586, SYH_ECOSE  ;
DR   B1LNG9, SYH_ECOSM  ;  Q1R8L9, SYH_ECOUT  ;  C5BET0, SYH_EDWI9  ;
DR   Q3YRB1, SYH_EHRCJ  ;  Q2GHH1, SYH_EHRCR  ;  Q5FG57, SYH_EHRRG  ;
DR   Q5HAI0, SYH_EHRRW  ;  B2KBC0, SYH_ELUMP  ;  A4WD92, SYH_ENT38  ;
DR   Q833I1, SYH_ENTFA  ;  Q6D277, SYH_ERWCT  ;  B2VE90, SYH_ERWT9  ;
DR   Q2N5U7, SYH_ERYLH  ;  B7LKC4, SYH_ESCF3  ;  C4L534, SYH_EXISA  ;
DR   A7HN13, SYH_FERNB  ;  B0S168, SYH_FINM2  ;  A5F9R5, SYH_FLAJ1  ;
DR   B0TWR5, SYH_FRAP2  ;  Q14K18, SYH_FRAT1  ;  A7NEI6, SYH_FRATF  ;
DR   Q2A1H0, SYH_FRATH  ;  B2SEW9, SYH_FRATM  ;  A0Q8F1, SYH_FRATN  ;
DR   Q0BK72, SYH_FRATO  ;  Q5NIL5, SYH_FRATT  ;  A4IW12, SYH_FRATW  ;
DR   Q8RGJ5, SYH_FUSNN  ;  Q5KWS8, SYH_GEOKA  ;  B3EB83, SYH_GEOLS  ;
DR   Q39UD2, SYH_GEOMG  ;  P60915, SYH_GEOSL  ;  C5D510, SYH_GEOSW  ;
DR   A4IR95, SYH_GEOTN  ;  Q7NHH9, SYH_GLOVI  ;  A9HJ49, SYH_GLUDA  ;
DR   Q5FUR8, SYH_GLUOX  ;  A0M0E2, SYH_GRAFK  ;  Q6B910, SYH_GRATL  ;
DR   Q7VME1, SYH_HAEDU  ;  Q4QNH3, SYH_HAEI8  ;  A5UAB7, SYH_HAEIE  ;
DR   A5UGH2, SYH_HAEIG  ;  P43823, SYH_HAEIN  ;  Q0I2E8, SYH_HAES1  ;
DR   B0USG9, SYH_HAES2  ;  A1WXZ0, SYH_HALHL  ;  B9LRS2, SYH_HALLT  ;
DR   Q5UXW4, SYH_HALMA  ;  B8CXE6, SYH_HALOH  ;  B0R6V2, SYH_HALS3  ;
DR   Q9HNP5, SYH_HALSA  ;  Q18DQ2, SYH_HALWD  ;  Q17VP5, SYH_HELAH  ;
DR   Q7VF68, SYH_HELHP  ;  B0TF88, SYH_HELMI  ;  B6JN30, SYH_HELP2  ;
DR   B5Z8I6, SYH_HELPG  ;  Q1CS74, SYH_HELPH  ;  Q9ZK27, SYH_HELPJ  ;
DR   B2UUV2, SYH_HELPS  ;  P56455, SYH_HELPY  ;  Q5QYB0, SYH_IDILO  ;
DR   Q28TV0, SYH_JANSC  ;  B5XNL6, SYH_KLEP3  ;  B1L6B4, SYH_KORCO  ;
DR   Q5FKI5, SYH_LACAC  ;  Q03SE4, SYH_LACBA  ;  Q038S0, SYH_LACC3  ;
DR   B3WEM3, SYH_LACCB  ;  Q1GAG8, SYH_LACDA  ;  Q04AV4, SYH_LACDB  ;
DR   B2GBY6, SYH_LACF3  ;  Q043X4, SYH_LACGA  ;  A8YUZ9, SYH_LACH4  ;
DR   P60916, SYH_LACJO  ;  Q9CE78, SYH_LACLA  ;  A2RN96, SYH_LACLM  ;
DR   Q02WI8, SYH_LACLS  ;  Q88VQ7, SYH_LACPL  ;  Q1WTV0, SYH_LACS1  ;
DR   Q38XB7, SYH_LACSS  ;  C1DD44, SYH_LARHH  ;  Q5X519, SYH_LEGPA  ;
DR   Q5ZV96, SYH_LEGPH  ;  Q5WWH1, SYH_LEGPL  ;  Q6ADR4, SYH_LEIXX  ;
DR   B0SH39, SYH_LEPBA  ;  Q04WC4, SYH_LEPBJ  ;  Q04X87, SYH_LEPBL  ;
DR   B0SQQ4, SYH_LEPBP  ;  P62371, SYH_LEPIC  ;  Q8F9Y3, SYH_LEPIN  ;
DR   Q92BJ3, SYH_LISIN  ;  Q71ZF0, SYH_LISMF  ;  Q8Y708, SYH_LISMO  ;
DR   B1HV72, SYH_LYSSC  ;  B9E707, SYH_MACCJ  ;  Q65R83, SYH_MANSM  ;
DR   A6VV07, SYH_MARMS  ;  Q6F199, SYH_MESFL  ;  A6UT01, SYH_META3  ;
DR   Q8TS62, SYH_METAC  ;  A7I940, SYH_METB6  ;  Q603B8, SYH_METCA  ;
DR   Q1H0V0, SYH_METFK  ;  Q2FTC5, SYH_METHJ  ;  Q58406, SYH_METJA  ;
DR   Q8TV61, SYH_METKA  ;  A2SQI5, SYH_METLZ  ;  A4G0V7, SYH_METM5  ;
DR   A9A947, SYH_METM6  ;  A6VHK3, SYH_METM7  ;  Q8PVB0, SYH_METMA  ;
DR   A3CVW4, SYH_METMJ  ;  P60921, SYH_METMP  ;  B8GDZ3, SYH_METPE  ;
DR   A4YJ03, SYH_METS5  ;  B8ER30, SYH_METSB  ;  O26346, SYH_METTH  ;
DR   A6UQQ6, SYH_METVS  ;  B0JRF1, SYH_MICAN  ;  C5CCH4, SYH_MICLC  ;
DR   Q2RHW0, SYH_MOOTA  ;  P67484, SYH_MYCBO  ;  A1KLS8, SYH_MYCBP  ;
DR   C1AF49, SYH_MYCBT  ;  Q2SSF4, SYH_MYCCT  ;  Q7NBS9, SYH_MYCGA  ;
DR   P47281, SYH_MYCGE  ;  Q601R3, SYH_MYCH2  ;  Q4A8C3, SYH_MYCH7  ;
DR   Q4AA96, SYH_MYCHJ  ;  P46696, SYH_MYCLE  ;  B2HN79, SYH_MYCMM  ;
DR   Q6KI17, SYH_MYCMO  ;  P62372, SYH_MYCMS  ;  P60917, SYH_MYCPA  ;
DR   Q8EWB8, SYH_MYCPE  ;  P75069, SYH_MYCPN  ;  Q98QM8, SYH_MYCPU  ;
DR   Q4A5X2, SYH_MYCS5  ;  A5U5T0, SYH_MYCTA  ;  P67483, SYH_MYCTU  ;
DR   A0PPE8, SYH_MYCUA  ;  A1T898, SYH_MYCVP  ;  P60922, SYH_NANEQ  ;
DR   Q3IMP5, SYH_NATPD  ;  B2A2F9, SYH_NATTJ  ;  Q5F9G8, SYH_NEIG1  ;
DR   A9M402, SYH_NEIM0  ;  Q9JUZ9, SYH_NEIMA  ;  Q9JZX9, SYH_NEIMB  ;
DR   A1KT95, SYH_NEIMF  ;  Q2GCZ0, SYH_NEOSM  ;  Q0AE43, SYH_NITEC  ;
DR   Q82XU9, SYH_NITEU  ;  A6Q371, SYH_NITSB  ;  Q5YTH9, SYH_NOCFA  ;
DR   B2J5J5, SYH_NOSP7  ;  Q8YMC2, SYH_NOSS1  ;  Q2GBN6, SYH_NOVAD  ;
DR   Q8EPR9, SYH_OCEIH  ;  P60918, SYH_ONYPE  ;  B1ZUW6, SYH_OPITP  ;
DR   A5CEP8, SYH_ORITB  ;  B3CTK8, SYH_ORITI  ;  P93422, SYH_ORYSJ  ;
DR   A6LIF7, SYH_PARD8  ;  A1B3C5, SYH_PARDP  ;  Q6ME90, SYH_PARUW  ;
DR   P57988, SYH_PASMU  ;  C6DBH3, SYH_PECCP  ;  Q03F51, SYH_PEDPA  ;
DR   Q3A5R6, SYH_PELCD  ;  Q3B1Z1, SYH_PELLD  ;  B4SCE2, SYH_PELPB  ;
DR   A1ANS7, SYH_PELPD  ;  A5D3E2, SYH_PELTS  ;  Q4FND9, SYH_PELUB  ;
DR   Q7N705, SYH_PHOLL  ;  P62373, SYH_PHOPR  ;  B1VA46, SYH_PHYAS  ;
DR   B3QZS0, SYH_PHYMT  ;  Q6L1Q5, SYH_PICTO  ;  Q7MTB3, SYH_PORGI  ;
DR   P51348, SYH_PORPU  ;  Q1XDD9, SYH_PORYE  ;  B4S4H1, SYH_PROA2  ;
DR   Q6A8J7, SYH_PROAC  ;  A3PBZ7, SYH_PROM0  ;  A2C182, SYH_PROM1  ;
DR   A2CCR1, SYH_PROM3  ;  A9B9Z7, SYH_PROM4  ;  A2BVT6, SYH_PROM5  ;
DR   Q31BR1, SYH_PROM9  ;  Q7VCG1, SYH_PROMA  ;  B4EZT2, SYH_PROMH  ;
DR   Q7V4P3, SYH_PROMM  ;  Q7V263, SYH_PROMP  ;  A2BQA4, SYH_PROMS  ;
DR   Q46LS5, SYH_PROMT  ;  A4SE02, SYH_PROVI  ;  Q48LZ3, SYH_PSE14  ;
DR   Q15R57, SYH_PSEA6  ;  A6V0W1, SYH_PSEA7  ;  B7UWI9, SYH_PSEA8  ;
DR   Q02RV6, SYH_PSEAB  ;  Q9HXJ5, SYH_PSEAE  ;  Q1IEI0, SYH_PSEE4  ;
DR   Q4K6V0, SYH_PSEF5  ;  C3K1L3, SYH_PSEFS  ;  Q3ICZ6, SYH_PSEHT  ;
DR   A4XY31, SYH_PSEMY  ;  A5VYT6, SYH_PSEP1  ;  Q3K7B7, SYH_PSEPF  ;
DR   B0KPI8, SYH_PSEPG  ;  Q88PJ6, SYH_PSEPK  ;  B1JDV7, SYH_PSEPW  ;
DR   Q886Y9, SYH_PSESM  ;  Q4ZX22, SYH_PSEU2  ;  A4VNX0, SYH_PSEU5  ;
DR   Q4FTW6, SYH_PSYA2  ;  Q1QD17, SYH_PSYCK  ;  A5WGQ0, SYH_PSYWF  ;
DR   Q9UY31, SYH_PYRAB  ;  Q8ZWZ1, SYH_PYRAE  ;  A4WIN2, SYH_PYRAR  ;
DR   A3MTI8, SYH_PYRCJ  ;  Q8U431, SYH_PYRFU  ;  O58028, SYH_PYRHO  ;
DR   A1RUZ2, SYH_PYRIL  ;  Q5JIM2, SYH_PYRKO  ;  Q8Y029, SYH_RALSO  ;
DR   Q1MKY0, SYH_RHIL3  ;  Q987T0, SYH_RHILO  ;  B5ZRD0, SYH_RHILW  ;
DR   Q92RR7, SYH_RHIME  ;  Q7UZ20, SYH_RHOBA  ;  C0ZZ58, SYH_RHOE4  ;
DR   C1B4E1, SYH_RHOOB  ;  P60919, SYH_RHOPA  ;  Q21AX3, SYH_RHOPB  ;
DR   B3QII5, SYH_RHOPT  ;  Q2RWE3, SYH_RHORT  ;  Q3IWD2, SYH_RHOS4  ;
DR   B9KU51, SYH_RHOSK  ;  Q0S1B6, SYH_RHOSR  ;  C3PN13, SYH_RICAE  ;
DR   A8GMY5, SYH_RICAH  ;  A8GVU9, SYH_RICB8  ;  Q1RJ50, SYH_RICBR  ;
DR   A8EZE6, SYH_RICCK  ;  Q92IK8, SYH_RICCN  ;  Q4UM71, SYH_RICFE  ;
DR   Q9ZDL9, SYH_RICPR  ;  C4K1W2, SYH_RICPU  ;  B0BWZ9, SYH_RICRO  ;
DR   Q68X64, SYH_RICTY  ;  Q160T4, SYH_ROSDO  ;  Q1AWC4, SYH_RUBXD  ;
DR   A1AWV6, SYH_RUTMC  ;  A4FBB7, SYH_SACEN  ;  B5F197, SYH_SALA4  ;
DR   A9MHL6, SYH_SALAR  ;  Q57LI7, SYH_SALCH  ;  B5FR62, SYH_SALDC  ;
DR   B5R581, SYH_SALEP  ;  B5RCZ1, SYH_SALG2  ;  B4TD92, SYH_SALHS  ;
DR   B4T0P8, SYH_SALNS  ;  Q5PNI1, SYH_SALPA  ;  A9N202, SYH_SALPB  ;
DR   C0PYN1, SYH_SALPC  ;  B5BAY6, SYH_SALPK  ;  B4TR94, SYH_SALSV  ;
DR   Q8Z4P4, SYH_SALTI  ;  O52765, SYH_SALTY  ;  O43011, SYH_SCHPO  ;
DR   A8GHW4, SYH_SERP5  ;  A1S862, SYH_SHEAM  ;  B8E9S8, SYH_SHEB2  ;
DR   A3D6V8, SYH_SHEB5  ;  A6WQP6, SYH_SHEB8  ;  A9KXK7, SYH_SHEB9  ;
DR   Q12PT3, SYH_SHEDO  ;  Q085U5, SYH_SHEFN  ;  B0TLI5, SYH_SHEHH  ;
DR   A3QCG3, SYH_SHELP  ;  Q8EC33, SYH_SHEON  ;  A8H246, SYH_SHEPA  ;
DR   A4Y8T9, SYH_SHEPC  ;  B8CKR2, SYH_SHEPW  ;  A0KUJ6, SYH_SHESA  ;
DR   A8FT71, SYH_SHESH  ;  Q0HKV8, SYH_SHESM  ;  Q0HX56, SYH_SHESR  ;
DR   A1RHQ4, SYH_SHESW  ;  B1KKJ3, SYH_SHEWM  ;  B2TXT9, SYH_SHIB3  ;
DR   Q31XX6, SYH_SHIBS  ;  Q32D48, SYH_SHIDS  ;  Q83K44, SYH_SHIFL  ;
DR   Q3YZ38, SYH_SHISS  ;  Q5LVN3, SYH_SILPO  ;  Q1GJD0, SYH_SILST  ;
DR   Q2NS41, SYH_SODGM  ;  Q028M4, SYH_SOLUE  ;  A9F907, SYH_SORC5  ;
DR   A7X345, SYH_STAA1  ;  A6U299, SYH_STAA2  ;  Q2FG96, SYH_STAA3  ;
DR   Q2FXU4, SYH_STAA8  ;  A5ITF5, SYH_STAA9  ;  Q2YT99, SYH_STAAB  ;
DR   Q5HFD2, SYH_STAAC  ;  A6QHH3, SYH_STAAE  ;  P60909, SYH_STAAM  ;
DR   P60910, SYH_STAAN  ;  Q6GG72, SYH_STAAR  ;  Q6G8T8, SYH_STAAS  ;
DR   A8Z2F8, SYH_STAAT  ;  P60911, SYH_STAAU  ;  P60912, SYH_STAAW  ;
DR   B9DNF9, SYH_STACT  ;  Q5HNS1, SYH_STAEQ  ;  Q8CS98, SYH_STAES  ;
DR   Q4L6X6, SYH_STAHJ  ;  Q49Y69, SYH_STAS1  ;  Q3JYL6, SYH_STRA1  ;
DR   P67485, SYH_STRA3  ;  P67486, SYH_STRA5  ;  Q827T0, SYH_STRAW  ;
DR   Q9KXP2, SYH_STRCO  ;  C0MB21, SYH_STRE4  ;  B4U0K6, SYH_STREM  ;
DR   P30053, SYH_STREQ  ;  A8AZV0, SYH_STRGC  ;  B1W3H3, SYH_STRGG  ;
DR   B4STN3, SYH_STRM5  ;  B2FPL6, SYH_STRMK  ;  Q8CWW2, SYH_STRMU  ;
DR   Q99XK9, SYH_STRP1  ;  Q04I50, SYH_STRP2  ;  P0DG40, SYH_STRP3  ;
DR   B5E3C8, SYH_STRP4  ;  Q5X9E5, SYH_STRP6  ;  C1CAV1, SYH_STRP7  ;
DR   Q8NZ19, SYH_STRP8  ;  A2RGY1, SYH_STRPG  ;  B1I9T7, SYH_STRPI  ;
DR   B8ZPP6, SYH_STRPJ  ;  Q48QS7, SYH_STRPM  ;  Q97NC9, SYH_STRPN  ;
DR   P0DG41, SYH_STRPQ  ;  B2IN41, SYH_STRPS  ;  B5XJ83, SYH_STRPZ  ;
DR   Q8DN46, SYH_STRR6  ;  A4VZ92, SYH_STRS2  ;  C0MGD4, SYH_STRS7  ;
DR   A3CR40, SYH_STRSV  ;  A4VT07, SYH_STRSY  ;  Q5LXM9, SYH_STRT1  ;
DR   Q5M281, SYH_STRT2  ;  Q03IB2, SYH_STRTD  ;  B9DW81, SYH_STRU0  ;
DR   C1CH52, SYH_STRZJ  ;  C1CNA0, SYH_STRZP  ;  C1CU26, SYH_STRZT  ;
DR   Q4JAY2, SYH_SULAC  ;  Q30RH3, SYH_SULDN  ;  C3MZH9, SYH_SULIA  ;
DR   C4KIQ9, SYH_SULIK  ;  C3MRE4, SYH_SULIL  ;  C3MY40, SYH_SULIM  ;
DR   C3NFX3, SYH_SULIN  ;  C3N7K1, SYH_SULIY  ;  A6Q9Z9, SYH_SULNB  ;
DR   P46220, SYH_SULSH  ;  Q980L3, SYH_SULSO  ;  Q975U9, SYH_SULTO  ;
DR   Q67LN9, SYH_SYMTH  ;  Q31KX6, SYH_SYNE7  ;  Q2JRX6, SYH_SYNJA  ;
DR   B1XJ88, SYH_SYNP2  ;  Q5N0Z5, SYH_SYNP6  ;  A5GIA4, SYH_SYNPW  ;
DR   Q7U9Q6, SYH_SYNPX  ;  A5GQA2, SYH_SYNR3  ;  Q0IDK4, SYH_SYNS3  ;
DR   Q3B0D3, SYH_SYNS9  ;  Q0AYS2, SYH_SYNWW  ;  Q55653, SYH_SYNY3  ;
DR   B7IHK5, SYH_THEAB  ;  Q9HLX5, SYH_THEAC  ;  Q8DHP7, SYH_THEEB  ;
DR   Q47RX0, SYH_THEFY  ;  A8F593, SYH_THELT  ;  A6LL06, SYH_THEM4  ;
DR   Q9X0H5, SYH_THEMA  ;  B1YCS2, SYH_THENV  ;  A5IN85, SYH_THEP1  ;
DR   B0K977, SYH_THEP3  ;  B0K0N4, SYH_THEPX  ;  B1L829, SYH_THESQ  ;
DR   P62374, SYH_THET2  ;  P56194, SYH_THET8  ;  Q8RAI8, SYH_THETN  ;
DR   Q97CE6, SYH_THEVO  ;  B5YHK1, SYH_THEYD  ;  Q31I05, SYH_THICR  ;
DR   Q3SL69, SYH_THIDA  ;  B8GTN4, SYH_THISH  ;  C4LC38, SYH_TOLAT  ;
DR   P60920, SYH_TREDE  ;  O83647, SYH_TREPA  ;  B2S3N0, SYH_TREPS  ;
DR   Q83H72, SYH_TROW8  ;  Q83FF5, SYH_TROWT  ;  B1H0I8, SYH_UNCTG  ;
DR   B1AIS5, SYH_UREP2  ;  Q9PQK6, SYH_UREPA  ;  B5ZB96, SYH_UREU1  ;
DR   A5CWE8, SYH_VESOH  ;  A5F3G1, SYH_VIBC3  ;  Q9KTX0, SYH_VIBCH  ;
DR   C3LT13, SYH_VIBCM  ;  Q5E771, SYH_VIBF1  ;  B5FAX3, SYH_VIBFM  ;
DR   A7MZE2, SYH_VIBHB  ;  Q87S15, SYH_VIBPA  ;  B7VJT9, SYH_VIBSL  ;
DR   Q8DEZ9, SYH_VIBVU  ;  Q7MNF0, SYH_VIBVY  ;  Q8D1Y2, SYH_WIGBR  ;
DR   P62351, SYH_WOLPM  ;  B3CLR6, SYH_WOLPP  ;  Q7M8S6, SYH_WOLSU  ;
DR   Q5GSM4, SYH_WOLTR  ;  C0R4G6, SYH_WOLWR  ;  Q8PLH2, SYH_XANAC  ;
DR   Q3BUG0, SYH_XANC5  ;  Q4UU37, SYH_XANC8  ;  Q8P9P5, SYH_XANCP  ;
DR   Q2P3K8, SYH_XANOM  ;  B2SKP3, SYH_XANOP  ;  Q5H0L6, SYH_XANOR  ;
DR   B2I5Y4, SYH_XYLF2  ;  Q9PBC2, SYH_XYLFA  ;  B0U3B6, SYH_XYLFM  ;
DR   Q87C26, SYH_XYLFT  ;  P07263, SYH_YEAST  ;  A1JKS3, SYH_YERE8  ;
DR   A7FFZ0, SYH_YERP3  ;  Q1C5I9, SYH_YERPA  ;  B2K9P9, SYH_YERPB  ;
DR   Q8ZCT6, SYH_YERPE  ;  A9R801, SYH_YERPG  ;  Q1CK90, SYH_YERPN  ;
DR   A4TMT6, SYH_YERPP  ;  Q668A0, SYH_YERPS  ;  B1JS06, SYH_YERPY  ;
//
ID   6.1.1.22
DE   Asparagine--tRNA ligase.
AN   Asparagine translase.
AN   Asparaginyl-tRNA synthetase.
CA   ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + L-asparaginyl-
CA   tRNA(Asn).
PR   PROSITE; PDOC00363;
DR   Q88Y40, SYN1_LACPL ;  Q88WA8, SYN2_LACPL ;  Q9SW96, SYNC1_ARATH;
DR   Q9SW95, SYNC2_ARATH;  Q9SSK1, SYNC3_ARATH;  Q2KJG3, SYNC_BOVIN ;
DR   P10723, SYNC_BRUMA ;  Q19722, SYNC_CAEEL ;  Q6BU46, SYNC_DEBHA ;
DR   Q554D9, SYNC_DICDI ;  Q8SQK8, SYNC_ENCCU ;  A9CTP8, SYNC_ENTBH ;
DR   O43776, SYNC_HUMAN ;  Q4R4Z1, SYNC_MACFA ;  Q8BP47, SYNC_MOUSE ;
DR   C4V847, SYNC_NOSCE ;  P41908, SYNC_SACDO ;  O94567, SYNC_SCHPO ;
DR   P38707, SYNC_YEAST ;  Q55FI3, SYNM_DICDI ;  Q96I59, SYNM_HUMAN ;
DR   Q8BGV0, SYNM_MOUSE ;  Q9P6I0, SYNM_SCHPO ;  P25345, SYNM_YEAST ;
DR   O48593, SYNO_ARATH ;  A9NE58, SYN_ACHLI  ;  Q1IHQ3, SYN_ACIBL  ;
DR   A3N039, SYN_ACTP2  ;  B3H198, SYN_ACTP7  ;  B0BNV4, SYN_ACTPJ  ;
DR   A6VNV7, SYN_ACTSZ  ;  A0KIC3, SYN_AERHH  ;  A6TVS9, SYN_ALKMQ  ;
DR   A8MJ91, SYN_ALKOO  ;  Q2NIF5, SYN_AYWBP  ;  B6YRL1, SYN_AZOPC  ;
DR   A7Z5Y7, SYN_BACA2  ;  Q81L32, SYN_BACAN  ;  Q72ZI3, SYN_BACC1  ;
DR   A7GTK8, SYN_BACCN  ;  Q817I8, SYN_BACCR  ;  Q633N6, SYN_BACCZ  ;
DR   Q5L8W2, SYN_BACFN  ;  Q64P24, SYN_BACFR  ;  Q9KC78, SYN_BACHD  ;
DR   Q6HCW9, SYN_BACHK  ;  Q65I63, SYN_BACLD  ;  Q5WGB1, SYN_BACSK  ;
DR   P39772, SYN_BACSU  ;  Q8A0Z8, SYN_BACTN  ;  A6L0U5, SYN_BACV8  ;
DR   Q1LT63, SYN_BAUCH  ;  Q7VR09, SYN_BLOFL  ;  Q492P3, SYN_BLOPB  ;
DR   Q0SP63, SYN_BORAP  ;  O51128, SYN_BORBU  ;  Q662R1, SYN_BORGA  ;
DR   P57441, SYN_BUCAI  ;  Q8K9I7, SYN_BUCAP  ;  P59517, SYN_BUCBP  ;
DR   A9WA97, SYN_CHLAA  ;  B8GBG7, SYN_CHLAD  ;  B9LCU8, SYN_CHLSY  ;
DR   Q97E56, SYN_CLOAB  ;  A7FRK8, SYN_CLOB1  ;  A6LPI6, SYN_CLOB8  ;
DR   B2UXS0, SYN_CLOBA  ;  B2TI01, SYN_CLOBB  ;  A5HZE1, SYN_CLOBH  ;
DR   A7GB01, SYN_CLOBL  ;  A5N4F7, SYN_CLOK5  ;  A0PY64, SYN_CLONN  ;
DR   Q0TMF3, SYN_CLOP1  ;  P58693, SYN_CLOPE  ;  Q0SQ51, SYN_CLOPS  ;
DR   Q899M9, SYN_CLOTE  ;  A3DBI2, SYN_CLOTH  ;  Q481G3, SYN_COLP3  ;
DR   Q11Q97, SYN_CYTH3  ;  C1CV26, SYN_DEIDV  ;  Q1IZA1, SYN_DEIGD  ;
DR   Q317J6, SYN_DESDG  ;  Q24MK1, SYN_DESHY  ;  Q6ANL4, SYN_DESPS  ;
DR   A4J412, SYN_DESRM  ;  Q72G53, SYN_DESVH  ;  A1V9B8, SYN_DESVV  ;
DR   A7ZK21, SYN_ECO24  ;  P58694, SYN_ECO57  ;  A7ZYN3, SYN_ECOHS  ;
DR   Q0TJC3, SYN_ECOL5  ;  P0A8M1, SYN_ECOL6  ;  B1IW01, SYN_ECOLC  ;
DR   P0A8M0, SYN_ECOLI  ;  Q1RDS7, SYN_ECOUT  ;  A4W8U9, SYN_ENT38  ;
DR   Q831X4, SYN_ENTFA  ;  Q6D453, SYN_ERWCT  ;  Q8RH70, SYN_FUSNN  ;
DR   Q39SY7, SYN_GEOMG  ;  Q74E08, SYN_GEOSL  ;  A4IQ54, SYN_GEOTN  ;
DR   A5G5R2, SYN_GEOUR  ;  Q7VLL7, SYN_HAEDU  ;  A5UCB9, SYN_HAEIE  ;
DR   A5UF16, SYN_HAEIG  ;  P43829, SYN_HAEIN  ;  B8F3Y5, SYN_HAEPS  ;
DR   Q0I2M9, SYN_HAES1  ;  B0UTU8, SYN_HAES2  ;  Q2SJV9, SYN_HAHCH  ;
DR   A9AYM5, SYN_HERA2  ;  Q5QZ13, SYN_IDILO  ;  A6T726, SYN_KLEP7  ;
DR   Q038W1, SYN_LACC3  ;  P54262, SYN_LACDA  ;  Q043G9, SYN_LACGA  ;
DR   A8YVJ7, SYN_LACH4  ;  Q74JA9, SYN_LACJO  ;  Q9CEK9, SYN_LACLA  ;
DR   A2RMQ1, SYN_LACLM  ;  Q02X21, SYN_LACLS  ;  A5VMP9, SYN_LACRD  ;
DR   B2GA02, SYN_LACRJ  ;  Q1WU36, SYN_LACS1  ;  Q38X65, SYN_LACSS  ;
DR   Q1MQG9, SYN_LAWIP  ;  Q5X300, SYN_LEGPA  ;  A5IE87, SYN_LEGPC  ;
DR   Q5WUG0, SYN_LEGPL  ;  Q04SB3, SYN_LEPBJ  ;  Q050D9, SYN_LEPBL  ;
DR   Q72QT4, SYN_LEPIC  ;  Q8F522, SYN_LEPIN  ;  Q92AB2, SYN_LISIN  ;
DR   Q71YB9, SYN_LISMF  ;  P58695, SYN_LISMO  ;  A0AK01, SYN_LISW6  ;
DR   Q65TR1, SYN_MANSM  ;  Q6F0Y5, SYN_MESFL  ;  B0JN99, SYN_MICAN  ;
DR   B3PNG8, SYN_MYCA5  ;  Q2SR42, SYN_MYCCT  ;  Q7NBM9, SYN_MYCGA  ;
DR   P47359, SYN_MYCGE  ;  Q600N9, SYN_MYCH2  ;  Q4A7W9, SYN_MYCH7  ;
DR   Q4A9S1, SYN_MYCHJ  ;  Q6KHD7, SYN_MYCMO  ;  Q6MUF2, SYN_MYCMS  ;
DR   Q8EW03, SYN_MYCPE  ;  P75521, SYN_MYCPN  ;  Q98PF2, SYN_MYCPU  ;
DR   Q1DA04, SYN_MYXXD  ;  P58692, SYN_NOSS1  ;  Q8EQE2, SYN_OCEIH  ;
DR   Q04EX6, SYN_OENOB  ;  Q6YPH3, SYN_ONYPE  ;  A6LIA1, SYN_PARD8  ;
DR   Q6MEC9, SYN_PARUW  ;  Q9CN06, SYN_PASMU  ;  A1APP8, SYN_PELPD  ;
DR   A5D2C2, SYN_PELTS  ;  Q7N622, SYN_PHOLL  ;  Q6LPQ6, SYN_PHOPR  ;
DR   B1V8X4, SYN_PHYAS  ;  B3R0I1, SYN_PHYMT  ;  B2RK42, SYN_PORG3  ;
DR   Q7MVE5, SYN_PORGI  ;  Q15UN9, SYN_PSEA6  ;  Q3IGU4, SYN_PSEHT  ;
DR   A1SW33, SYN_PSYIN  ;  Q9V251, SYN_PYRAB  ;  Q8U4D3, SYN_PYRFU  ;
DR   O57980, SYN_PYRHO  ;  Q5JHC1, SYN_PYRKO  ;  Q7UHE1, SYN_RHOBA  ;
DR   A7NHQ4, SYN_ROSCS  ;  A5UPW5, SYN_ROSS1  ;  Q57QZ8, SYN_SALCH  ;
DR   Q5PGF0, SYN_SALPA  ;  Q56112, SYN_SALTI  ;  P58696, SYN_SALTY  ;
DR   A8GCJ5, SYN_SERP5  ;  A1S684, SYN_SHEAM  ;  A3D3V7, SYN_SHEB5  ;
DR   A6WMP4, SYN_SHEB8  ;  A9KZ30, SYN_SHEB9  ;  Q12MT5, SYN_SHEDO  ;
DR   Q081Q0, SYN_SHEFN  ;  B0TUU1, SYN_SHEHH  ;  A3QE68, SYN_SHELP  ;
DR   Q8EEZ1, SYN_SHEON  ;  A8H467, SYN_SHEPA  ;  A4Y6E4, SYN_SHEPC  ;
DR   A0KXL6, SYN_SHESA  ;  A8FVU8, SYN_SHESH  ;  Q0HIB6, SYN_SHESM  ;
DR   Q0HUL3, SYN_SHESR  ;  A1RK52, SYN_SHESW  ;  Q31YR7, SYN_SHIBS  ;
DR   Q32E51, SYN_SHIDS  ;  Q0T6B1, SYN_SHIF8  ;  P0A8M2, SYN_SHIFL  ;
DR   Q3Z3J0, SYN_SHISS  ;  Q2NU85, SYN_SODGM  ;  Q023P9, SYN_SOLUE  ;
DR   A9GBR2, SYN_SORC5  ;  A7X2E9, SYN_STAA1  ;  A6U1S3, SYN_STAA2  ;
DR   Q2FGY6, SYN_STAA3  ;  Q2FYH6, SYN_STAA8  ;  A5ISY4, SYN_STAA9  ;
DR   Q2YY52, SYN_STAAB  ;  Q5HFW9, SYN_STAAC  ;  A6QH05, SYN_STAAE  ;
DR   P67571, SYN_STAAM  ;  P67572, SYN_STAAN  ;  Q6GGV5, SYN_STAAR  ;
DR   Q6G9A8, SYN_STAAS  ;  A8Z434, SYN_STAAT  ;  Q8NWP3, SYN_STAAW  ;
DR   Q5HP89, SYN_STAEQ  ;  Q8CSI9, SYN_STAES  ;  Q4L6F8, SYN_STAHJ  ;
DR   Q49XR0, SYN_STAS1  ;  Q3K2E5, SYN_STRA1  ;  P67573, SYN_STRA3  ;
DR   P67574, SYN_STRA5  ;  Q8DTM2, SYN_STRMU  ;  P67575, SYN_STRP1  ;
DR   Q04JK7, SYN_STRP2  ;  P0DG28, SYN_STRP3  ;  Q5XD20, SYN_STRP6  ;
DR   P67577, SYN_STRP8  ;  Q1JCQ7, SYN_STRPB  ;  Q1JMN3, SYN_STRPC  ;
DR   Q1JHS6, SYN_STRPD  ;  Q1J7K5, SYN_STRPF  ;  A2RFM5, SYN_STRPG  ;
DR   Q48UH6, SYN_STRPM  ;  Q97PR0, SYN_STRPN  ;  P0DG29, SYN_STRPQ  ;
DR   Q8CWQ4, SYN_STRR6  ;  A4W083, SYN_STRS2  ;  A3CNM0, SYN_STRSV  ;
DR   A4VTZ1, SYN_STRSY  ;  Q5M067, SYN_STRT1  ;  Q5M4S8, SYN_STRT2  ;
DR   Q03L20, SYN_STRTD  ;  Q67P26, SYN_SYMTH  ;  A0LL53, SYN_SYNFM  ;
DR   B1XKH1, SYN_SYNP2  ;  P52276, SYN_SYNY3  ;  Q9HKS7, SYN_THEAC  ;
DR   Q8DG51, SYN_THEEB  ;  C5A4R8, SYN_THEGJ  ;  Q72KF7, SYN_THET2  ;
DR   P54263, SYN_THET8  ;  Q979Y4, SYN_THEVO  ;  Q73P19, SYN_TREDE  ;
DR   O83618, SYN_TREPA  ;  B2S3J9, SYN_TREPS  ;  B1AJ04, SYN_UREP2  ;
DR   Q9PQC6, SYN_UREPA  ;  B5ZBH7, SYN_UREU1  ;  Q9KSF9, SYN_VIBCH  ;
DR   Q5E5P2, SYN_VIBF1  ;  Q87NH5, SYN_VIBPA  ;  Q8DAF0, SYN_VIBVU  ;
DR   Q7MJS0, SYN_VIBVY  ;  Q8D2U1, SYN_WIGBR  ;  Q8PM16, SYN_XANAC  ;
DR   Q3BV23, SYN_XANC5  ;  Q4UTA1, SYN_XANC8  ;  Q8PAC4, SYN_XANCP  ;
DR   Q2P326, SYN_XANOM  ;  Q5H049, SYN_XANOR  ;  Q9PAF5, SYN_XYLFA  ;
DR   Q87A82, SYN_XYLFT  ;  A1JMN8, SYN_YERE8  ;  A7FJU5, SYN_YERP3  ;
DR   Q1CA47, SYN_YERPA  ;  P58697, SYN_YERPE  ;  Q1CGI7, SYN_YERPN  ;
DR   A4TMZ6, SYN_YERPP  ;  Q66CG7, SYN_YERPS  ;
//
ID   6.1.1.23
DE   Aspartate--tRNA(Asn) ligase.
AN   Nondiscriminating aspartyl-tRNA synthetase.
CA   ATP + L-aspartate + tRNA(Asx) = AMP + diphosphate + aspartyl-tRNA(Asx).
CC   -!- When this enzyme acts on tRNA(Asp), it catalyzes the same reaction as
CC       EC 6.1.1.12.
CC   -!- It has, however, diminished discrimination, so that it can also form
CC       aspartyl-tRNA(Asn).
CC   -!- This relaxation of specificity has been found to result from the
CC       absence of a loop in the tRNA that specifically recognizes the third
CC       position of the anticodon.
CC   -!- This accounts for the ability of this enzyme in, for example, Thermus
CC       thermophilus, to recognize both tRNA(Asp) (GUC anticodon) and
CC       tRNA(Asn) (GUU anticodon).
CC   -!- The aspartate-tRNA(Asn) is not used in protein synthesis until it is
CC       converted by EC 6.3.5.6 into asparaginyl-tRNA(Asn).
//
ID   6.1.1.24
DE   Glutamate--tRNA(Gln) ligase.
AN   Nondiscriminating glutamyl-tRNA synthetase.
CA   ATP + L-glutamate + tRNA(Glx) = AMP + diphosphate + glutamyl-tRNA(Glx).
CC   -!- When this enzyme acts on tRNA(Glu), it catalyzes the same reaction as
CC       EC 6.1.1.17.
CC   -!- It has, however, diminished discrimination, so that it can also form
CC       glutamate-tRNA(Gln).
CC   -!- This relaxation of specificity has been found to result from the
CC       absence of a loop in the tRNA that specifically recognizes the third
CC       position of the anticodon.
CC   -!- This accounts for the ability of this enzyme in, for example,
CC       Bacillus subtilis, to recognize both tRNA(1)(Gln) (UUG anticodon) and
CC       tRNA(Glu) (UUC anticodon) but not tRNA(2)(Gln) (CUG anticodon).
CC   -!- The ability of this enzyme to recognize both tRNA(Glu) and one of the
CC       tRNA(Gln) isoacceptors derives from their sharing a major identity
CC       element, a hypermodified derivative of U34 (5-methylaminomethyl-2-
CC       thiouridine).
CC   -!- The glutamyl-tRNA(Gln) is not used in protein synthesis until it is
CC       converted by EC 6.3.5.7 into glutaminyl-tRNA(Gln).
//
ID   6.1.1.25
DE   Lysine--tRNA(Pyl) ligase.
CA   ATP + L-lysine + tRNA(Pyl) = AMP + diphosphate + L-lysyl-tRNA(Pyl).
CC   -!- In organisms such as Methanosarcina barkeri that incorporate the
CC       modified amino acid pyrrolysine (Pyl) into certain methylamine
CC       methyltransferases, an unusual tRNA(Pyl), with a CUA anticodon,
CC       is charged directly with pyrrolysine by this class II aminoacyl--tRNA
CC       ligase.
CC   -!- The tRNA and the ligase are encoded within the same gene cluster,
CC       and the ligase does not appear to be closely related to EC 6.1.1.6.
//
ID   6.1.1.26
DE   Pyrrolysine--tRNA(Pyl) ligase.
AN   PylRS.
AN   Pyrrolysyl-tRNA synthetase.
CA   ATP + L-pyrrolysine + tRNA(Pyl) = AMP + diphosphate + L-pyrrolysyl-
CA   tRNA(Pyl).
CC   -!- In organisms such as Methanosarcina barkeri that incorporate the
CC       modified amino acid pyrrolysine (Pyl) into certain methylamine
CC       methyltransferases, an unusual tRNA(Pyl), with a CUA anticodon,
CC       can be charged directly with pyrrolysine by this class II aminoacyl-
CC       -tRNA ligase.
CC   -!- Specific for pyrrolysine as substrate as it cannot be replaced by
CC       lysine or any of the other natural amino acids.
DR   Q8TUB8, PYLS_METAC ;  Q6WRH6, PYLS_METBA ;  Q46E77, PYLS_METBF ;
DR   Q12UB6, PYLS_METBU ;  Q8PWY1, PYLS_METMA ;  Q1L6A3, PYLS_METTE ;
//
ID   6.1.1.27
DE   O-phosphoserine--tRNA ligase.
AN   O-phosphoseryl-tRNA ligase.
AN   SepRS.
CA   ATP + O-phospho-L-serine + tRNA(Cys) = AMP + diphosphate + O-phospho-L-
CA   seryl-tRNA(Cys).
CC   -!- In organisms like Archaeoglobus fulgidus lacking EC 6.1.1.16 for the
CC       direct Cys-tRNA(Cys) formation, Cys-tRNA(Cys) is produced by an
CC       indirect pathway, in which EC 6.1.1.27 ligates O-phosphoserine to
CC       tRNA(Cys), and EC 2.5.1.73 converts the produced O-phospho-L-seryl-
CC       tRNA(Cys) to Cys-tRNA(Cys).
CC   -!- The SepRS/SepCysS pathway is the sole route for cysteine biosynthesis
CC       in the organism.
CC   -!- Methanosarcina mazei can use both pathways, the direct route using
CC       EC 6.1.1.16 and the indirect pathway with EC 6.1.1.27 and
CC       EC 2.5.1.73.
CC   -!- Formerly EC 6.1.1.n2.
PR   PROSITE; PDOC00363;
DR   O30126, SEPS_ARCFU ;  A6UVW6, SEPS_META3 ;  Q8TUH7, SEPS_METAC ;
DR   A7I4Y4, SEPS_METB6 ;  Q46D71, SEPS_METBF ;  Q12XG0, SEPS_METBU ;
DR   Q2FSR2, SEPS_METHJ ;  Q59054, SEPS_METJA ;  Q8TY66, SEPS_METKA ;
DR   A2SQV5, SEPS_METLZ ;  A4FYB1, SEPS_METM5 ;  A9A794, SEPS_METM6 ;
DR   A6VJZ5, SEPS_METM7 ;  Q8PX39, SEPS_METMA ;  A3CXN8, SEPS_METMJ ;
DR   Q6LZE1, SEPS_METMP ;  B8GJL9, SEPS_METPE ;  O27545, SEPS_METTH ;
DR   A0B632, SEPS_METTP ;  A6USJ0, SEPS_METVS ;  Q0W0T4, SEPS_UNCMA ;
//
ID   6.1.1.n1
DE   Transferred entry: 6.3.1.13.
//
ID   6.1.1.n2
DE   Transferred entry: 6.1.1.27.
//
ID   6.1.2.1
DE   D-alanine--(R)-lactate ligase.
CA   D-alanine + (R)-lactate + ATP = D-alanyl-(R)-lactate + ADP + phosphate.
CC   -!- The product of this enzyme, the depsipeptide D-alanyl-(R)-lactate,
CC       can be incorporated into the peptidoglycan pentapeptide instead of
CC       the usual D-alanyl-D-alanine dipeptide, which is formed by
CC       EC 6.3.2.4.
CC   -!- The resulting peptidoglycan does not bind the glycopeptide
CC       antibiotics vancomycin and teicoplanin, conferring resistance on the
CC       bacteria.
DR   P25051, VANA_ENTFC ;  Q06893, VANB_ENTFA ;
//
ID   6.2.1.1
DE   Acetate--CoA ligase.
AN   Acetate thiokinase.
AN   Acetyl-activating enzyme.
AN   Acetyl-CoA synthase.
AN   Acetyl-CoA synthetase.
AN   Acyl-activating enzyme.
CA   ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.
CC   -!- Also acts on propanoate and propenoate.
PR   PROSITE; PDOC00427;
DR   Q758X0, ACS1_ASHGO ;  O94049, ACS1_CANAL ;  Q6FLU2, ACS1_CANGA ;
DR   Q6BQF2, ACS1_DEBHA ;  O60011, ACS1_KLULA ;  Q01574, ACS1_YEAST ;
DR   Q9NUB1, ACS2L_HUMAN;  Q99NB1, ACS2L_MOUSE;  Q750T7, ACS2_ASHGO ;
DR   Q8NJN3, ACS2_CANAL ;  Q6FXI2, ACS2_CANGA ;  Q6BS00, ACS2_DEBHA ;
DR   Q9Y7B5, ACS2_KLULA ;  P52910, ACS2_YEAST ;  Q96VC7, ACS2_ZYGBA ;
DR   Q9I558, ACSA1_PSEAE;  Q88EH6, ACSA1_PSEPK;  Q9HV66, ACSA2_PSEAE;
DR   Q88DW6, ACSA2_PSEPK;  Q92KX2, ACSA2_RHIME;  A0KNI2, ACSA_AERHH ;
DR   A4SJM6, ACSA_AERS4 ;  Q9KWA3, ACSA_AGRRH ;  B9JEV4, ACSA_AGRRK ;
DR   Q8UBV5, ACSA_AGRT5 ;  B9JV43, ACSA_AGRVS ;  Q0VSR6, ACSA_ALCBS ;
DR   Q0AAW0, ACSA_ALHEH ;  P39062, ACSA_BACSU ;  A1UR36, ACSA_BARBK ;
DR   Q6G1W0, ACSA_BARHE ;  Q6FYL4, ACSA_BARQU ;  A9IYZ3, ACSA_BART1 ;
DR   Q6MNF1, ACSA_BDEBA ;  B2IB12, ACSA_BEII9 ;  Q89WV5, ACSA_BRAJA ;
DR   A4YK73, ACSA_BRASO ;  B2S7N5, ACSA_BRUA1 ;  Q2YLH5, ACSA_BRUA2 ;
DR   Q57B76, ACSA_BRUAB ;  A9M849, ACSA_BRUC2 ;  C0RF62, ACSA_BRUMB ;
DR   Q8YJ48, ACSA_BRUME ;  A5VSF3, ACSA_BRUO2 ;  A9WWT6, ACSA_BRUSI ;
DR   Q8FYQ3, ACSA_BRUSU ;  A3MG40, ACSA_BURM7 ;  A2RYW5, ACSA_BURM9 ;
DR   Q62AD1, ACSA_BURMA ;  A1UWN5, ACSA_BURMS ;  A3P2K7, ACSA_BURP0 ;
DR   Q3JH62, ACSA_BURP1 ;  A3NH07, ACSA_BURP6 ;  B2JD61, ACSA_BURP8 ;
DR   Q63NC4, ACSA_BURPS ;  Q39EK2, ACSA_BURS3 ;  Q2T3N9, ACSA_BURTA ;
DR   A8FNJ7, ACSA_CAMJ8 ;  Q9PMD2, ACSA_CAMJE ;  A1W1D6, ACSA_CAMJJ ;
DR   Q9A2I0, ACSA_CAUCR ;  Q8KBY0, ACSA_CHLTE ;  Q7NSY7, ACSA_CHRVO ;
DR   A8AN29, ACSA_CITK8 ;  A8PDE3, ACSA_COPC7 ;  O13440, ACSA_COPCI ;
DR   Q27549, ACSA_CRYPV ;  P31638, ACSA_CUPNH ;  Q46Z41, ACSA_CUPPJ ;
DR   B3R1X2, ACSA_CUPTR ;  Q9RRL7, ACSA_DEIRA ;  B8FIN2, ACSA_DESAA ;
DR   Q54Z60, ACSA_DICDI ;  Q9VP61, ACSA_DROME ;  Q8X5T5, ACSA_ECO57 ;
DR   Q8FAY8, ACSA_ECOL6 ;  P27550, ACSA_ECOLI ;  P16928, ACSA_EMENI ;
DR   A7MPJ7, ACSA_ENTS8 ;  C1AA44, ACSA_GEMAT ;  A1WY97, ACSA_HALHL ;
DR   Q17WR1, ACSA_HELAH ;  B6JKX8, ACSA_HELP2 ;  B5Z6E9, ACSA_HELPG ;
DR   Q1CUA3, ACSA_HELPH ;  O25686, ACSA_HELPY ;  A4G3L8, ACSA_HERAR ;
DR   Q9NR19, ACSA_HUMAN ;  C1D6V9, ACSA_LARHH ;  B0S8X7, ACSA_LEPBA ;
DR   Q04P35, ACSA_LEPBJ ;  Q056J9, ACSA_LEPBL ;  B0SRX5, ACSA_LEPBP ;
DR   Q72LY9, ACSA_LEPIC ;  Q8EYG2, ACSA_LEPIN ;  A0L576, ACSA_MAGSM ;
DR   A1U2S9, ACSA_MARAV ;  A6VZN8, ACSA_MARMS ;  B7KPN8, ACSA_METC4 ;
DR   A9W5V0, ACSA_METEP ;  Q1H0J2, ACSA_METFK ;  B1ZB59, ACSA_METPB ;
DR   B1M0M1, ACSA_METRJ ;  B8EPJ0, ACSA_METSB ;  P27095, ACSA_METSO ;
DR   Q9QXG4, ACSA_MOUSE ;  P59871, ACSA_MYCBO ;  O69635, ACSA_MYCTU ;
DR   P16929, ACSA_NEUCR ;  Q0AFF1, ACSA_NITEC ;  Q82SI5, ACSA_NITEU ;
DR   Q93LL2, ACSA_NOSLI ;  Q2G512, ACSA_NOVAD ;  A6WXV8, ACSA_OCHA4 ;
DR   A7HSR8, ACSA_PARL1 ;  Q9CMW1, ACSA_PASMU ;  P36333, ACSA_PENCH ;
DR   Q7MBA6, ACSA_PHOLL ;  Q6LLZ1, ACSA_PHOPR ;  Q01576, ACSA_PHYBL ;
DR   Q9F7R5, ACSA_PRB01 ;  Q48G09, ACSA_PSE14 ;  Q15YI8, ACSA_PSEA6 ;
DR   Q3IFM6, ACSA_PSEHT ;  Q885K7, ACSA_PSESM ;  Q4ZQG8, ACSA_PSEU2 ;
DR   A4VKA0, ACSA_PSEU5 ;  Q4FVA1, ACSA_PSYA2 ;  Q1QEB6, ACSA_PSYCK ;
DR   A1SZA2, ACSA_PSYIN ;  O93730, ACSA_PYRAE ;  A4WJG1, ACSA_PYRAR ;
DR   Q1LL27, ACSA_RALME ;  B2U6V1, ACSA_RALPJ ;  Q8XY11, ACSA_RALSO ;
DR   B3PS41, ACSA_RHIE6 ;  Q2K2T1, ACSA_RHIEC ;  Q98ET8, ACSA_RHILO ;
DR   B5ZV36, ACSA_RHILW ;  C3MAS0, ACSA_RHISN ;  P59872, ACSA_RHOBA ;
DR   O68040, ACSA_RHOCB ;  Q07VK4, ACSA_RHOP5 ;  Q1AXQ5, ACSA_RUBXD ;
DR   Q21LV0, ACSA_SACD2 ;  Q8Z1R0, ACSA_SALTI ;  Q8ZKF6, ACSA_SALTY ;
DR   P78773, ACSA_SCHPO ;  A8G8G7, ACSA_SERP5 ;  A1S7C8, ACSA_SHEAM ;
DR   A3D3E8, ACSA_SHEB5 ;  A6WM52, ACSA_SHEB8 ;  A9KY56, ACSA_SHEB9 ;
DR   Q12MK0, ACSA_SHEDO ;  Q084J4, ACSA_SHEFN ;  B0TPY4, ACSA_SHEHH ;
DR   A3QD52, ACSA_SHELP ;  Q8EDK3, ACSA_SHEON ;  A8H5P1, ACSA_SHEPA ;
DR   A4Y7Y7, ACSA_SHEPC ;  A0KY83, ACSA_SHESA ;  A8FUF1, ACSA_SHESH ;
DR   Q0HHN4, ACSA_SHESM ;  Q0HTY6, ACSA_SHESR ;  A1RIK1, ACSA_SHESW ;
DR   A6UED8, ACSA_SINMW ;  Q2NR28, ACSA_SODGM ;  Q82EL5, ACSA_STRAW ;
DR   Q9X928, ACSA_STRCO ;  Q2LW77, ACSA_SYNAS ;  A0LG91, ACSA_SYNFM ;
DR   Q55404, ACSA_SYNY3 ;  Q8DKH2, ACSA_THEEB ;  Q72J95, ACSA_THET2 ;
DR   Q5SIW6, ACSA_THET8 ;  Q3SLF4, ACSA_THIDA ;  Q9KV59, ACSA_VIBCH ;
DR   Q87KU7, ACSA_VIBPA ;  Q8DCZ9, ACSA_VIBVU ;  Q7MGU3, ACSA_VIBVY ;
DR   Q7M9Y2, ACSA_WOLSU ;  Q8PF09, ACSA_XANAC ;  Q4UP35, ACSA_XANC8 ;
DR   Q8P3L1, ACSA_XANCP ;  Q2NXE2, ACSA_XANOM ;  A7IFD4, ACSA_XANP2 ;
DR   Q9PB89, ACSA_XYLFA ;  Q87C00, ACSA_XYLFT ;  A1JIK3, ACSA_YERE8 ;
DR   A7FNG1, ACSA_YERP3 ;  Q1C0N0, ACSA_YERPA ;  Q8D1G8, ACSA_YERPE ;
DR   Q1CE37, ACSA_YERPN ;  A4TS06, ACSA_YERPP ;  Q66FM8, ACSA_YERPS ;
DR   Q554Z5, ACSB_DICDI ;  A7MB45, ACSS3_BOVIN;  Q9H6R3, ACSS3_HUMAN;
DR   Q14DH7, ACSS3_MOUSE;  Q5REB8, ACSS3_PONAB;
//
ID   6.2.1.2
DE   Butyrate--CoA ligase.
AN   Acyl-activating enzyme.
AN   Butyryl-CoA synthetase.
AN   Fatty acid thiokinase (medium chain).
CA   ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA.
CC   -!- Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy-
CC       and 2,3- or 3,4-unsaturated acids.
DR   Q08AH3, ACS2A_HUMAN;  Q68CK6, ACS2B_HUMAN;  Q9BEA2, ACSM1_BOVIN;
DR   Q08AH1, ACSM1_HUMAN;  Q91VA0, ACSM1_MOUSE;  Q8K0L3, ACSM2_MOUSE;
DR   O70490, ACSM2_RAT  ;  Q53FZ2, ACSM3_HUMAN;  Q3UNX5, ACSM3_MOUSE;
DR   Q5REV5, ACSM3_PONAB;  Q6SKG1, ACSM3_RAT  ;  P0C7M7, ACSM4_HUMAN;
DR   Q80W40, ACSM4_MOUSE;  Q7TN78, ACSM4_RAT  ;  Q6NUN0, ACSM5_HUMAN;
DR   Q8BGA8, ACSM5_MOUSE;  Q6AYT9, ACSM5_RAT  ;  Q6P461, ACSM6_HUMAN;
//
ID   6.2.1.3
DE   Long-chain-fatty-acid--CoA ligase.
AN   Acyl-activating enzyme.
AN   Acyl-CoA synthetase.
AN   Fatty acid thiokinase (long chain).
AN   Lignoceroyl-CoA synthase.
CA   ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-
CA   CoA.
CC   -!- Acts on a wide range of long-chain saturated and unsaturated fatty
CC       acids, but the enzymes from different tissues show some variation in
CC       specificity.
CC   -!- The liver enzyme acts on acids from C(6) to C(20); that from brain
CC       shows high activity up to C(24).
PR   PROSITE; PDOC00427;
DR   Q2KHW5, ACBG1_BOVIN;  Q96GR2, ACBG1_HUMAN;  Q4R4P9, ACBG1_MACFA;
DR   Q99PU5, ACBG1_MOUSE;  Q924N5, ACBG1_RAT  ;  Q5ZKR7, ACBG2_CHICK;
DR   Q5FVE4, ACBG2_HUMAN;  Q2XU92, ACBG2_MOUSE;  A1L1K7, ACBG2_RAT  ;
DR   Q7ZYC4, ACBG2_XENLA;  Q9JID6, ACSL1_CAVPO;  P33121, ACSL1_HUMAN;
DR   P41216, ACSL1_MOUSE;  P18163, ACSL1_RAT  ;  O95573, ACSL3_HUMAN;
DR   Q9CZW4, ACSL3_MOUSE;  Q5R668, ACSL3_PONAB;  Q63151, ACSL3_RAT  ;
DR   O60488, ACSL4_HUMAN;  Q9QUJ7, ACSL4_MOUSE;  O35547, ACSL4_RAT  ;
DR   Q9ULC5, ACSL5_HUMAN;  Q8JZR0, ACSL5_MOUSE;  O88813, ACSL5_RAT  ;
DR   Q9UKU0, ACSL6_HUMAN;  Q91WC3, ACSL6_MOUSE;  P33124, ACSL6_RAT  ;
DR   Q9V3U0, BGML_DROME ;  Q9V3S9, BGM_DROME  ;  Q7TYX8, FAC15_MYCBO;
DR   B2HGV4, FAC15_MYCMM;  O53521, FAC15_MYCTU;  Q7TWC5, FAC17_MYCBO;
DR   B2HHZ8, FAC17_MYCMM;  O53551, FAC17_MYCTU;  Q7TWB7, FAC19_MYCBO;
DR   B2HI05, FAC19_MYCMM;  Q7D5D8, FAC19_MYCTU;  Q7TVK7, FAC23_MYCBO;
DR   O07797, FAC23_MYCTU;  Q55DR6, FCSA_DICDI ;  Q1ZXQ4, FCSB_DICDI ;
DR   O22898, LACS1_ARATH;  Q9XIA9, LACS2_ARATH;  Q9C7W4, LACS3_ARATH;
DR   Q9T0A0, LACS4_ARATH;  Q9T009, LACS5_ARATH;  Q8LPS1, LACS6_ARATH;
DR   Q8LKS5, LACS7_ARATH;  Q9SJD4, LACS8_ARATH;  Q9CAP8, LACS9_ARATH;
DR   O60135, LCF1_SCHPO ;  P30624, LCF1_YEAST ;  Q9P7D7, LCF2_SCHPO ;
DR   P39518, LCF2_YEAST ;  P39002, LCF3_YEAST ;  P47912, LCF4_YEAST ;
DR   P94547, LCFA_BACSU ;  Q8XDR6, LCFA_ECO57 ;  P69452, LCFA_ECOL6 ;
DR   P69451, LCFA_ECOLI ;  P46450, LCFA_HAEIN ;  P63522, LCFA_SALTI ;
DR   P63521, LCFA_SALTY ;  Q8ZES9, LCFA_YERPE ;  O07610, LCFB_BACSU ;
DR   P44446, LCFH_HAEIN ;  O14975, S27A2_HUMAN;  O35488, S27A2_MOUSE;
DR   P97524, S27A2_RAT  ;
//
ID   6.2.1.4
DE   Succinate--CoA ligase (GDP-forming).
AN   Succinyl-CoA synthetase (GDP-forming).
CA   GTP + succinate + CoA = GDP + phosphate + succinyl-CoA.
CC   -!- Itaconate can act instead of succinate and ITP instead of GTP.
PR   PROSITE; PDOC00335;
DR   P53399, SUCA1_TRIVA;  P53400, SUCA2_TRIVA;  P53401, SUCA3_TRIVA;
DR   Q58DR8, SUCA_BOVIN ;  P53596, SUCA_CAEEL ;  P36967, SUCA_DICDI ;
DR   Q94522, SUCA_DROME ;  P53597, SUCA_HUMAN ;  Q9WUM5, SUCA_MOUSE ;
DR   Q9P727, SUCA_NEUCR ;  O19069, SUCA_PIG   ;  P13086, SUCA_RAT   ;
DR   O13750, SUCA_SCHPO ;  Q3MHX5, SUCB2_BOVIN;  P53589, SUCB2_CAEEL;
DR   Q869S7, SUCB2_DICDI;  Q96I99, SUCB2_HUMAN;  Q9Z2I8, SUCB2_MOUSE;
DR   P53590, SUCB2_PIG  ;  P53587, SUCB_NEOFR ;  Q9P567, SUCB_NEUCR ;
DR   O94415, SUCB_SCHPO ;  Q03184, SUCB_TRIVA ;
//
ID   6.2.1.5
DE   Succinate--CoA ligase (ADP-forming).
AN   Succinate thiokinase.
AN   Succinyl-CoA synthetase (ADP-forming).
CA   ATP + succinate + CoA = ADP + phosphate + succinyl-CoA.
PR   PROSITE; PDOC00335;
PR   PROSITE; PDOC50975;
DR   P68209, SUCA1_ARATH;  Q8GTQ9, SUCA1_SOLLC;  Q8LAD2, SUCA2_ARATH;
DR   Q6DQL1, SUCA2_SOLLC;  Q6ZL94, SUCA_ORYSJ ;  P53598, SUCA_YEAST ;
DR   Q148D5, SUCB1_BOVIN;  P53588, SUCB1_CAEEL;  P99507, SUCB1_CANFA;
DR   Q55AI5, SUCB1_DICDI;  Q9P2R7, SUCB1_HUMAN;  Q4R517, SUCB1_MACFA;
DR   P86226, SUCB1_MESAU;  Q9Z2I9, SUCB1_MOUSE;  O97580, SUCB1_PIG  ;
DR   O82662, SUCB_ARATH ;  Q6K9N6, SUCB_ORYSJ ;  Q84LB6, SUCB_SOLLC ;
DR   P53312, SUCB_YEAST ;  O28732, SUCC1_ARCFU;  Q9KY56, SUCC1_STRCO;
DR   O28097, SUCC2_ARCFU;  O87840, SUCC2_STRCO;  A1TW81, SUCC_ACIAC ;
DR   Q6F8L4, SUCC_ACIAD ;  B7GXK7, SUCC_ACIB3 ;  B7I6T2, SUCC_ACIB5 ;
DR   B2HXG0, SUCC_ACIBC ;  Q1IJS5, SUCC_ACIBL ;  B0VSL0, SUCC_ACIBS ;
DR   A3M887, SUCC_ACIBT ;  B0VEF2, SUCC_ACIBY ;  A0LRU4, SUCC_ACIC1 ;
DR   C1F2F2, SUCC_ACIC5 ;  A5FYZ9, SUCC_ACICJ ;  B9MHW0, SUCC_ACIET ;
DR   B7J4G8, SUCC_ACIF2 ;  B5EMG2, SUCC_ACIF5 ;  A1WD26, SUCC_ACISJ ;
DR   A3MZH0, SUCC_ACTP2 ;  B3GX29, SUCC_ACTP7 ;  B0BTV5, SUCC_ACTPJ ;
DR   A6VPM2, SUCC_ACTSZ ;  A0KJK9, SUCC_AERHH ;  A4SND2, SUCC_AERS4 ;
DR   B9JCF4, SUCC_AGRRK ;  Q8UC60, SUCC_AGRT5 ;  B9JTS8, SUCC_AGRVS ;
DR   B2UMH5, SUCC_AKKM8 ;  Q0VPF7, SUCC_ALCBS ;  Q0A5K0, SUCC_ALHEH ;
DR   B6EHV6, SUCC_ALISL ;  A6TKJ3, SUCC_ALKMQ ;  A8MM16, SUCC_ALKOO ;
DR   B4RYG2, SUCC_ALTMD ;  B8JAE0, SUCC_ANAD2 ;  Q2IIC1, SUCC_ANADE ;
DR   Q5PBI8, SUCC_ANAMM ;  Q2GJ42, SUCC_ANAPZ ;  B4UDP4, SUCC_ANASK ;
DR   O67546, SUCC_AQUAE ;  Q5P7A7, SUCC_AROAE ;  A1R3M0, SUCC_ARTAT ;
DR   B8HDC2, SUCC_ARTCA ;  A0JT43, SUCC_ARTS2 ;  A1KAU3, SUCC_AZOSB ;
DR   C1DM53, SUCC_AZOVD ;  A7Z4M9, SUCC_BACA2 ;  C3P5N7, SUCC_BACAA ;
DR   C3L791, SUCC_BACAC ;  A0RHK9, SUCC_BACAH ;  Q81WK0, SUCC_BACAN ;
DR   Q732N4, SUCC_BACC1 ;  B7IUJ5, SUCC_BACC2 ;  C1EP60, SUCC_BACC3 ;
DR   B7HDV9, SUCC_BACC4 ;  B7HLG9, SUCC_BACC7 ;  A7GRG6, SUCC_BACCN ;
DR   B9IVC5, SUCC_BACCQ ;  Q819X0, SUCC_BACCR ;  Q636J0, SUCC_BACCZ ;
DR   Q5LCW4, SUCC_BACFN ;  Q64U25, SUCC_BACFR ;  Q9KA20, SUCC_BACHD ;
DR   Q6HEX9, SUCC_BACHK ;  Q65JP0, SUCC_BACLD ;  A8FD73, SUCC_BACP2 ;
DR   Q5WFP4, SUCC_BACSK ;  P80886, SUCC_BACSU ;  Q8A9M7, SUCC_BACTN ;
DR   A9VT74, SUCC_BACWK ;  A1UQV9, SUCC_BARBK ;  Q6G1M1, SUCC_BARHE ;
DR   Q6FYD1, SUCC_BARQU ;  A9IZV3, SUCC_BART1 ;  Q1LTZ4, SUCC_BAUCH ;
DR   Q6MGW1, SUCC_BDEBA ;  C5BZT2, SUCC_BEUC1 ;  Q2KYF7, SUCC_BORA1 ;
DR   Q7WKM5, SUCC_BORBR ;  Q7W789, SUCC_BORPA ;  A9IKE3, SUCC_BORPD ;
DR   Q7VVU5, SUCC_BORPE ;  Q89X60, SUCC_BRAJA ;  A5E936, SUCC_BRASB ;
DR   A4YKC6, SUCC_BRASO ;  C0ZFB3, SUCC_BREBN ;  B2S880, SUCC_BRUA1 ;
DR   Q57AX2, SUCC_BRUAB ;  A9M8R2, SUCC_BRUC2 ;  C0RFH1, SUCC_BRUMB ;
DR   P66867, SUCC_BRUME ;  A5VSQ3, SUCC_BRUO2 ;  B0CIT0, SUCC_BRUSI ;
DR   P66868, SUCC_BRUSU ;  B1YVY6, SUCC_BURA4 ;  Q1BTW6, SUCC_BURCA ;
DR   B1JY14, SUCC_BURCC ;  A0KA72, SUCC_BURCH ;  B4EBY6, SUCC_BURCJ ;
DR   Q0BC71, SUCC_BURCM ;  A9AFT3, SUCC_BURM1 ;  A3MH60, SUCC_BURM7 ;
DR   A2S8U3, SUCC_BURM9 ;  Q62MG7, SUCC_BURMA ;  A1V6W8, SUCC_BURMS ;
DR   A3NRX7, SUCC_BURP0 ;  Q3JVL5, SUCC_BURP1 ;  A3N693, SUCC_BURP6 ;
DR   B2SYE8, SUCC_BURPP ;  Q63WW2, SUCC_BURPS ;  Q39D96, SUCC_BURS3 ;
DR   Q2T0U7, SUCC_BURTA ;  A4JHJ8, SUCC_BURVG ;  Q13UH9, SUCC_BURXL ;
DR   A7GYI5, SUCC_CAMC5 ;  A0RPE8, SUCC_CAMFF ;  A7I2F2, SUCC_CAMHC ;
DR   A8FKV6, SUCC_CAMJ8 ;  A7H4K9, SUCC_CAMJD ;  Q9PHY1, SUCC_CAMJE ;
DR   A1VYP2, SUCC_CAMJJ ;  Q5HVN3, SUCC_CAMJR ;  B8GYZ1, SUCC_CAUCN ;
DR   Q9AB94, SUCC_CAUCR ;  B0T3D1, SUCC_CAUSK ;  A9WJ74, SUCC_CHLAA ;
DR   Q5L593, SUCC_CHLAB ;  B8GCC9, SUCC_CHLAD ;  Q3ATR4, SUCC_CHLCH ;
DR   Q822A1, SUCC_CHLCV ;  Q255N7, SUCC_CHLFF ;  B3EFL3, SUCC_CHLL2 ;
DR   Q9PL99, SUCC_CHLMU ;  B3QPP2, SUCC_CHLP8 ;  B3EN95, SUCC_CHLPB ;
DR   A1BE51, SUCC_CHLPD ;  Q9Z6T6, SUCC_CHLPN ;  B9LB77, SUCC_CHLSY ;
DR   B0B950, SUCC_CHLT2 ;  B3QWF8, SUCC_CHLT3 ;  Q3KKL8, SUCC_CHLTA ;
DR   B0BAS9, SUCC_CHLTB ;  Q8KFE7, SUCC_CHLTE ;  O84828, SUCC_CHLTR ;
DR   Q7NZ47, SUCC_CHRVO ;  A5CU44, SUCC_CLAM3 ;  Q482S1, SUCC_COLP3 ;
DR   Q8NMK7, SUCC_CORGL ;  B6J8N7, SUCC_COXB1 ;  B6IZ97, SUCC_COXB2 ;
DR   A9KBQ4, SUCC_COXBN ;  A9N8R8, SUCC_COXBR ;  P53592, SUCC_COXBU ;
DR   Q0KE75, SUCC_CUPNH ;  Q475M1, SUCC_CUPPJ ;  B2AHC1, SUCC_CUPTR ;
DR   Q47AN8, SUCC_DECAR ;  C1CV60, SUCC_DEIDV ;  Q1IZE7, SUCC_DEIGD ;
DR   Q9RUY3, SUCC_DEIRA ;  A9BQA5, SUCC_DELAS ;  B8FLW6, SUCC_DESAA ;
DR   C0QLM0, SUCC_DESAH ;  B8D5I6, SUCC_DESK1 ;  A8ZRW7, SUCC_DESOH ;
DR   Q6ARL2, SUCC_DESPS ;  A5EX54, SUCC_DICNV ;  A7ZJA8, SUCC_ECO24 ;
DR   B7LAD4, SUCC_ECO55 ;  P0A838, SUCC_ECO57 ;  B5YQR7, SUCC_ECO5E ;
DR   B7NMS9, SUCC_ECO7I ;  B7M5P1, SUCC_ECO8A ;  C4ZWK2, SUCC_ECOBW ;
DR   B1X6Q8, SUCC_ECODH ;  A7ZXY8, SUCC_ECOHS ;  P0A837, SUCC_ECOL6 ;
DR   B1IY02, SUCC_ECOLC ;  P0A836, SUCC_ECOLI ;  B7N9W6, SUCC_ECOLU ;
DR   B6I7Z9, SUCC_ECOSE ;  B1LLG1, SUCC_ECOSM ;  C5BEM7, SUCC_EDWI9 ;
DR   Q3YSV6, SUCC_EHRCJ ;  Q2GFL7, SUCC_EHRCR ;  Q5FH54, SUCC_EHRRG ;
DR   Q5HC25, SUCC_EHRRW ;  A4W879, SUCC_ENT38 ;  A7MQX5, SUCC_ENTS8 ;
DR   Q6D7G2, SUCC_ERWCT ;  B2VBR6, SUCC_ERWT9 ;  Q2N695, SUCC_ERYLH ;
DR   B1YIL7, SUCC_EXIS2 ;  C4L610, SUCC_EXISA ;  A5FHX8, SUCC_FLAJ1 ;
DR   A6GY30, SUCC_FLAPJ ;  B0TZ23, SUCC_FRAP2 ;  Q2JFA7, SUCC_FRASC ;
DR   A8LAW3, SUCC_FRASN ;  Q14IV5, SUCC_FRAT1 ;  A7NDR1, SUCC_FRATF ;
DR   Q2A253, SUCC_FRATH ;  B2SDM1, SUCC_FRATM ;  A0Q5H4, SUCC_FRATN ;
DR   Q0BKS4, SUCC_FRATO ;  Q5NHF3, SUCC_FRATT ;  A4IZC2, SUCC_FRATW ;
DR   C1A8X8, SUCC_GEMAT ;  Q5L0N7, SUCC_GEOKA ;  B3E7B3, SUCC_GEOLS ;
DR   Q74EA5, SUCC_GEOSL ;  C5D8V2, SUCC_GEOSW ;  A4IM83, SUCC_GEOTN ;
DR   A0LZD4, SUCC_GRAFK ;  Q4QLA3, SUCC_HAEI8 ;  A5UCR4, SUCC_HAEIE ;
DR   A5UIW0, SUCC_HAEIG ;  P45101, SUCC_HAEIN ;  B8F4Q2, SUCC_HAEPS ;
DR   Q0I3A8, SUCC_HAES1 ;  B0UUF3, SUCC_HAES2 ;  Q2SD35, SUCC_HAHCH ;
DR   A1WZ92, SUCC_HALHL ;  B9LRR0, SUCC_HALLT ;  Q5V4Q4, SUCC_HALMA ;
DR   B0R5U5, SUCC_HALS3 ;  Q9HPP1, SUCC_HALSA ;  C4K7D7, SUCC_HAMD5 ;
DR   A9B0I2, SUCC_HERA2 ;  A4G230, SUCC_HERAR ;  B4U901, SUCC_HYDS0 ;
DR   Q0C5F3, SUCC_HYPNA ;  Q5QU21, SUCC_IDILO ;  A8A8L8, SUCC_IGNH4 ;
DR   A6SUY3, SUCC_JANMA ;  Q28U74, SUCC_JANSC ;  B5XZD1, SUCC_KLEP3 ;
DR   A6T6F6, SUCC_KLEP7 ;  B2GM49, SUCC_KOCRD ;  C1DB55, SUCC_LARHH ;
DR   Q5X7K6, SUCC_LEGPA ;  A5IH21, SUCC_LEGPC ;  Q5WZ04, SUCC_LEGPL ;
DR   Q6AD57, SUCC_LEIXX ;  B0SAP0, SUCC_LEPBA ;  Q04QS3, SUCC_LEPBJ ;
DR   Q053V6, SUCC_LEPBL ;  Q72PA2, SUCC_LEPIC ;  Q8F746, SUCC_LEPIN ;
DR   B9EBC7, SUCC_MACCJ ;  Q2W063, SUCC_MAGSA ;  Q65SV1, SUCC_MANSM ;
DR   A1TZS9, SUCC_MARAV ;  Q0AKU3, SUCC_MARMM ;  A6VZ30, SUCC_MARMS ;
DR   Q11CV8, SUCC_MESSB ;  Q1H031, SUCC_METFK ;  Q57663, SUCC_METJA ;
DR   O27115, SUCC_METTH ;  C5C916, SUCC_MICLC ;  A0QBP0, SUCC_MYCA1 ;
DR   B1MJJ0, SUCC_MYCA9 ;  Q7U0Z1, SUCC_MYCBO ;  A1KH85, SUCC_MYCBP ;
DR   C1ALT7, SUCC_MYCBT ;  A4T6V7, SUCC_MYCGI ;  B8ZU00, SUCC_MYCLB ;
DR   Q9Z5H8, SUCC_MYCLE ;  B2HED1, SUCC_MYCMM ;  A0R3M4, SUCC_MYCS2 ;
DR   A3Q5P5, SUCC_MYCSJ ;  A1UL96, SUCC_MYCSK ;  Q1B3V2, SUCC_MYCSS ;
DR   A5U0Z1, SUCC_MYCTA ;  P71559, SUCC_MYCTU ;  A0PWD1, SUCC_MYCUA ;
DR   A1TEP3, SUCC_MYCVP ;  Q1D6I9, SUCC_MYXXD ;  Q3INN3, SUCC_NATPD ;
DR   B9L5I6, SUCC_NAUPA ;  Q5F878, SUCC_NEIG1 ;  B4RL77, SUCC_NEIG2 ;
DR   A9M4F8, SUCC_NEIM0 ;  Q9JUT0, SUCC_NEIMA ;  Q9JZP4, SUCC_NEIMB ;
DR   A1KTM6, SUCC_NEIMF ;  Q2GEF1, SUCC_NEOSM ;  Q1QQR3, SUCC_NITHX ;
DR   A6Q391, SUCC_NITSB ;  Q3SVK4, SUCC_NITWN ;  Q5YPP8, SUCC_NOCFA ;
DR   A1SMQ5, SUCC_NOCSJ ;  Q2G3G8, SUCC_NOVAD ;  A6WXE8, SUCC_OCHA4 ;
DR   B6JE33, SUCC_OLICO ;  B1ZP17, SUCC_OPITP ;  A5CC52, SUCC_ORITB ;
DR   B3CTW0, SUCC_ORITI ;  A1AZH7, SUCC_PARDP ;  A7HT39, SUCC_PARL1 ;
DR   Q6MBM7, SUCC_PARUW ;  Q9CNZ0, SUCC_PASMU ;  C6DCD6, SUCC_PECCP ;
DR   Q3A7Y4, SUCC_PELCD ;  Q3B5J6, SUCC_PELLD ;  B4SEH6, SUCC_PELPB ;
DR   A1APQ8, SUCC_PELPD ;  Q4FP29, SUCC_PELUB ;  C0QQH3, SUCC_PERMH ;
DR   B4RCH3, SUCC_PHEZH ;  Q7N6V5, SUCC_PHOLL ;  Q6LTB5, SUCC_PHOPR ;
DR   A1VUC0, SUCC_POLNA ;  B1XRZ4, SUCC_POLNS ;  Q122H7, SUCC_POLSJ ;
DR   A4SZY0, SUCC_POLSQ ;  B4S612, SUCC_PROA2 ;  Q6A6Y0, SUCC_PROAC ;
DR   B4ESR1, SUCC_PROMH ;  A4SDL6, SUCC_PROVI ;  Q48K68, SUCC_PSE14 ;
DR   Q15UW6, SUCC_PSEA6 ;  A6V7K5, SUCC_PSEA7 ;  B7UVD3, SUCC_PSEA8 ;
DR   Q02K73, SUCC_PSEAB ;  P53593, SUCC_PSEAE ;  Q1I7L3, SUCC_PSEE4 ;
DR   Q4KFY6, SUCC_PSEF5 ;  C3K6N0, SUCC_PSEFS ;  Q3IGW5, SUCC_PSEHT ;
DR   A4XV90, SUCC_PSEMY ;  A5W114, SUCC_PSEP1 ;  Q3KFU6, SUCC_PSEPF ;
DR   B0KNW8, SUCC_PSEPG ;  Q88FB2, SUCC_PSEPK ;  B1JAV3, SUCC_PSEPW ;
DR   Q883Z4, SUCC_PSESM ;  Q4ZUW7, SUCC_PSEU2 ;  A4VKQ1, SUCC_PSEU5 ;
DR   Q4FVH9, SUCC_PSYA2 ;  Q1QEK5, SUCC_PSYCK ;  A1SWX6, SUCC_PSYIN ;
DR   A5WC33, SUCC_PSYWF ;  Q8ZVF3, SUCC_PYRAE ;  A4WL16, SUCC_PYRAR ;
DR   A3MWQ7, SUCC_PYRCJ ;  A1RTB8, SUCC_PYRIL ;  B2UGE2, SUCC_RALPJ ;
DR   Q8Y1Y3, SUCC_RALSO ;  A9WKU9, SUCC_RENSM ;  B3PQ90, SUCC_RHIE6 ;
DR   Q2K3F0, SUCC_RHIEC ;  Q1MAW1, SUCC_RHIL3 ;  Q98EC5, SUCC_RHILO ;
DR   B5ZSR9, SUCC_RHILW ;  Q9EYG9, SUCC_RHIME ;  Q7UKI3, SUCC_RHOBA ;
DR   B6IP72, SUCC_RHOCS ;  C1A3F2, SUCC_RHOE4 ;  Q21RF9, SUCC_RHOFD ;
DR   C1AWW6, SUCC_RHOOB ;  Q2J3G9, SUCC_RHOP2 ;  Q07UX6, SUCC_RHOP5 ;
DR   Q6NDB7, SUCC_RHOPA ;  Q21CW8, SUCC_RHOPB ;  Q13DR5, SUCC_RHOPS ;
DR   B3Q760, SUCC_RHOPT ;  Q2RV33, SUCC_RHORT ;  A3PN13, SUCC_RHOS1 ;
DR   Q3IZ84, SUCC_RHOS4 ;  A4WNM6, SUCC_RHOS5 ;  B9KNB3, SUCC_RHOSK ;
DR   Q0S533, SUCC_RHOSR ;  C3PNF9, SUCC_RICAE ;  A8GNF5, SUCC_RICAH ;
DR   A8GUV0, SUCC_RICB8 ;  Q1RH55, SUCC_RICBR ;  A8EYY8, SUCC_RICCK ;
DR   Q92I21, SUCC_RICCN ;  Q4ULQ7, SUCC_RICFE ;  A8F1K7, SUCC_RICM5 ;
DR   O05966, SUCC_RICPR ;  C4K0K1, SUCC_RICPU ;  B0BXJ5, SUCC_RICRO ;
DR   A8GS29, SUCC_RICRS ;  Q68WU5, SUCC_RICTY ;  A7NNW3, SUCC_ROSCS ;
DR   A5V080, SUCC_ROSS1 ;  Q1AWI8, SUCC_RUBXD ;  A1AVI3, SUCC_RUTMC ;
DR   Q21IW6, SUCC_SACD2 ;  A4FP60, SUCC_SACEN ;  B5EZG1, SUCC_SALA4 ;
DR   A8M469, SUCC_SALAI ;  A9MJL9, SUCC_SALAR ;  Q57RL3, SUCC_SALCH ;
DR   B5FNF9, SUCC_SALDC ;  B5QWG8, SUCC_SALEP ;  B5R689, SUCC_SALG2 ;
DR   B4TBD7, SUCC_SALHS ;  B4SZE2, SUCC_SALNS ;  Q5PCM7, SUCC_SALPA ;
DR   A9MTQ2, SUCC_SALPB ;  C0PWE7, SUCC_SALPC ;  B5BC72, SUCC_SALPK ;
DR   Q2S3H9, SUCC_SALRD ;  B4TQ53, SUCC_SALSV ;  P66870, SUCC_SALTI ;
DR   A4XBE5, SUCC_SALTO ;  P66869, SUCC_SALTY ;  A8GB83, SUCC_SERP5 ;
DR   A1S5I0, SUCC_SHEAM ;  B8E770, SUCC_SHEB2 ;  A3D5J3, SUCC_SHEB5 ;
DR   A6WPA4, SUCC_SHEB8 ;  A9L532, SUCC_SHEB9 ;  Q12M63, SUCC_SHEDO ;
DR   Q080X8, SUCC_SHEFN ;  B0TJP8, SUCC_SHEHH ;  A3QDH6, SUCC_SHELP ;
DR   Q8EFN8, SUCC_SHEON ;  A8H3H6, SUCC_SHEPA ;  A4Y7Q5, SUCC_SHEPC ;
DR   B8CR00, SUCC_SHEPW ;  A0KVX6, SUCC_SHESA ;  A8FX46, SUCC_SHESH ;
DR   Q0HJQ4, SUCC_SHESM ;  Q0HW00, SUCC_SHESR ;  A1RIT3, SUCC_SHESW ;
DR   B1KPH0, SUCC_SHEWM ;  B2TUB2, SUCC_SHIB3 ;  Q324I4, SUCC_SHIBS ;
DR   Q32IK3, SUCC_SHIDS ;  Q0T6W6, SUCC_SHIF8 ;  P0A839, SUCC_SHIFL ;
DR   Q3Z476, SUCC_SHISS ;  A6UDP2, SUCC_SINMW ;  Q2NUM2, SUCC_SODGM ;
DR   Q021N6, SUCC_SOLUE ;  A9GD65, SUCC_SORC5 ;  A5VB78, SUCC_SPHWW ;
DR   A7X1L8, SUCC_STAA1 ;  A6U164, SUCC_STAA2 ;  Q2FHJ3, SUCC_STAA3 ;
DR   Q2FZ37, SUCC_STAA8 ;  A5ISD0, SUCC_STAA9 ;  Q2YXM1, SUCC_STAAB ;
DR   Q5HGI7, SUCC_STAAC ;  A6QGE5, SUCC_STAAE ;  P66871, SUCC_STAAM ;
DR   P99071, SUCC_STAAN ;  Q6GHJ0, SUCC_STAAR ;  Q6G9W8, SUCC_STAAS ;
DR   A8Z3S5, SUCC_STAAT ;  P66872, SUCC_STAAW ;  B9DPG0, SUCC_STACT ;
DR   Q5HPU5, SUCC_STAEQ ;  Q8CPH5, SUCC_STAES ;  Q4L5U8, SUCC_STAHJ ;
DR   A3DLR9, SUCC_STAMF ;  Q49X32, SUCC_STAS1 ;  B1W3P6, SUCC_STRGG ;
DR   B4ST72, SUCC_STRM5 ;  B2FRS3, SUCC_STRMK ;  Q30RQ3, SUCC_SULDN ;
DR   A6Q7S7, SUCC_SULNB ;  B2V8I4, SUCC_SULSY ;  A0LIY8, SUCC_SYNFM ;
DR   C5BL83, SUCC_TERTT ;  P25126, SUCC_THETH ;  Q31FV4, SUCC_THICR ;
DR   Q3SKM1, SUCC_THIDA ;  B8GN38, SUCC_THISH ;  C4L8V5, SUCC_TOLAT ;
DR   A1WLG5, SUCC_VEREI ;  A5F6G6, SUCC_VIBC3 ;  Q9KQB5, SUCC_VIBCH ;
DR   C3LP35, SUCC_VIBCM ;  Q5E6M6, SUCC_VIBF1 ;  B5FC28, SUCC_VIBFM ;
DR   A7N158, SUCC_VIBHB ;  Q87RE8, SUCC_VIBPA ;  B7VI35, SUCC_VIBSL ;
DR   Q8DFQ1, SUCC_VIBVU ;  Q7MMN3, SUCC_VIBVY ;  Q73FW3, SUCC_WOLPM ;
DR   B3CME9, SUCC_WOLPP ;  Q7M9A6, SUCC_WOLSU ;  Q5GSB6, SUCC_WOLTR ;
DR   C0R4N4, SUCC_WOLWR ;  Q8PHL5, SUCC_XANAC ;  Q3BQ83, SUCC_XANC5 ;
DR   Q4UXU0, SUCC_XANC8 ;  B0RPQ9, SUCC_XANCB ;  Q8P676, SUCC_XANCP ;
DR   Q2P5E6, SUCC_XANOM ;  B2ST87, SUCC_XANOP ;  Q5H2H4, SUCC_XANOR ;
DR   B2I9R4, SUCC_XYLF2 ;  Q9PAH1, SUCC_XYLFA ;  B0U5F8, SUCC_XYLFM ;
DR   Q87A98, SUCC_XYLFT ;  A1JRB6, SUCC_YERE8 ;  A7FKR4, SUCC_YERP3 ;
DR   Q1CAG1, SUCC_YERPA ;  B2K8F1, SUCC_YERPB ;  Q8ZH00, SUCC_YERPE ;
DR   A9R2F2, SUCC_YERPG ;  Q1CFM0, SUCC_YERPN ;  A4TNT8, SUCC_YERPP ;
DR   Q66DA0, SUCC_YERPS ;  B1JG57, SUCC_YERPY ;  Q5NMF5, SUCC_ZYMMO ;
DR   O28733, SUCD1_ARCFU;  O28098, SUCD2_ARCFU;  O67547, SUCD_AQUAE ;
DR   P80865, SUCD_BACSU ;  P53591, SUCD_COXBU ;  P0AGF1, SUCD_ECO57 ;
DR   P0AGF0, SUCD_ECOL6 ;  P0AGE9, SUCD_ECOLI ;  P45102, SUCD_HAEIN ;
DR   Q58643, SUCD_METJA ;  O26663, SUCD_METTH ;  Q7U0Z0, SUCD_MYCBO ;
DR   P71558, SUCD_MYCTU ;  Q51567, SUCD_PSEAE ;  Q1RH56, SUCD_RICBR ;
DR   Q92I22, SUCD_RICCN ;  Q4ULQ8, SUCD_RICFE ;  O08371, SUCD_RICPR ;
DR   Q9AKE1, SUCD_RICTY ;  Q5HGI6, SUCD_STAAC ;  P66866, SUCD_STAAM ;
DR   P99070, SUCD_STAAN ;  Q6GHI9, SUCD_STAAR ;  Q6G9W7, SUCD_STAAS ;
DR   Q8NX01, SUCD_STAAW ;  Q5HPU4, SUCD_STAEQ ;  Q8CPH4, SUCD_STAES ;
DR   P09143, SUCD_THETH ;
//
ID   6.2.1.6
DE   Glutarate--CoA ligase.
AN   Glutaryl-CoA synthetase.
CA   ATP + glutarate + CoA = ADP + phosphate + glutaryl-CoA.
CC   -!- GTP or ITP can act instead of ATP.
//
ID   6.2.1.7
DE   Cholate--CoA ligase.
AN   3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate--CoA ligase.
AN   3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate:CoA ligase (AMP-
AN   forming).
AN   3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoate-CoA ligase.
AN   3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoate-CoA synthetase.
AN   3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl coenzyme A
AN   synthetase.
AN   BAL.
AN   Bile acid CoA ligase.
AN   Bile acid coenzyme A ligase.
AN   Cholate thiokinase.
AN   Cholic acid:CoA ligase.
AN   Cholic thiokinase.
AN   Choloyl coenzyme A synthetase.
AN   Choloyl-CoA synthetase.
AN   Cholyl-CoA synthetase.
AN   THCA-CoA ligase.
AN   Trihydroxycoprostanoyl-CoA synthetase.
CA   (1) ATP + cholate + CoA = AMP + diphosphate + choloyl-CoA.
CA   (2) ATP + (25R)-3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-
CA   oate + CoA = AMP + diphosphate + (25R)-3-alpha,7-alpha,12-alpha-
CA   trihydroxy-5-beta-cholestanoyl-CoA.
CF   Magnesium.
CC   -!- This membrane-bound enzyme catalyzes the first step in the
CC       conjugation of bile acids with amino acids, converting bile acids
CC       into their acyl-CoA thioesters.
CC   -!- The second step involves EC 2.3.1.65 and converts the acyl-CoA
CC       thioester into the corresponding N-acyl amidate by conjugation with
CC       glycine or taurine.
CC   -!- Chenodeoxycholate, deoxycholate, lithocholate and
CC       trihydroxycoprostanoate can also act as substrates.
CC   -!- Formerly EC 6.2.1.29.
DR   Q9Y2P5, S27A5_HUMAN;  Q4LDG0, S27A5_MOUSE;  Q9ES38, S27A5_RAT  ;
//
ID   6.2.1.8
DE   Oxalate--CoA ligase.
AN   Oxalyl-CoA synthetase.
CA   ATP + oxalate + CoA = AMP + diphosphate + oxalyl-CoA.
//
ID   6.2.1.9
DE   Malate--CoA ligase.
AN   Malate thiokinase.
AN   Malyl-CoA synthetase.
CA   ATP + malate + CoA = ADP + phosphate + malyl-CoA.
DR   P53594, MTKA_METEA ;  Q98KT9, MTKA_RHILO ;  P53595, MTKB_METEA ;
//
ID   6.2.1.10
DE   Acid--CoA ligase (GDP-forming).
AN   Acyl-CoA synthetase (GDP-forming).
CA   GTP + an acid + CoA = GDP + phosphate + acyl-CoA.
//
ID   6.2.1.11
DE   Biotin--CoA ligase.
AN   Biotinyl-CoA synthetase.
CA   ATP + biotin + CoA = AMP + diphosphate + biotinyl-CoA.
//
ID   6.2.1.12
DE   4-coumarate--CoA ligase.
AN   4-coumaroyl-CoA synthase.
AN   4-coumaryl-CoA synthetase.
CA   ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA.
PR   PROSITE; PDOC00427;
DR   Q42524, 4CL1_ARATH ;  Q54P77, 4CL1_DICDI ;  P17814, 4CL1_ORYSJ ;
DR   P14912, 4CL1_PETCR ;  P31684, 4CL1_SOLTU ;  P31686, 4CL1_SOYBN ;
DR   O24145, 4CL1_TOBAC ;  Q9S725, 4CL2_ARATH ;  Q54P78, 4CL2_DICDI ;
DR   Q42982, 4CL2_ORYSJ ;  P14913, 4CL2_PETCR ;  P31685, 4CL2_SOLTU ;
DR   P31687, 4CL2_SOYBN ;  O24146, 4CL2_TOBAC ;  Q9S777, 4CL3_ARATH ;
DR   Q54P79, 4CL3_DICDI ;  Q6ETN3, 4CL3_ORYSJ ;  Q9LU36, 4CL4_ARATH ;
DR   Q67W82, 4CL4_ORYSJ ;  Q6ZAC1, 4CL5_ORYSJ ;  P41636, 4CL_PINTA  ;
DR   O24540, 4CL_VANPL  ;  P42516, PCL_HALHA  ;  O69140, PCL_RHOCB  ;
DR   O54075, PCL_RHOS4  ;
//
ID   6.2.1.13
DE   Acetate--CoA ligase (ADP-forming).
AN   Acetate thiokinase.
AN   Acetyl-CoA synthetase (ADP-forming).
CA   ATP + acetate + CoA = ADP + phosphate + acetyl-CoA.
CC   -!- Also acts on propanoate and, very slowly, on butanoate.
//
ID   6.2.1.14
DE   6-carboxyhexanoate--CoA ligase.
AN   6-carboxyhexanoyl-CoA synthetase.
AN   Pimeloyl-CoA synthetase.
CA   ATP + 6-carboxyhexanoate + CoA = AMP + diphosphate + 6-carboxyhexanoyl-
CA   CoA.
DR   C4LK80, BIOWF_CORK4;  Q6A6M4, BIOWF_PROAC;  D4H9Y2, BIOWF_PROAS;
DR   O67575, BIOW_AQUAE ;  E3E2E2, BIOW_BACA1 ;  A7Z5B6, BIOW_BACA2 ;
DR   Q70JY7, BIOW_BACAM ;  E1UV19, BIOW_BACAS ;  Q65ML3, BIOW_BACLD ;
DR   D3G0V0, BIOW_BACPE ;  E0TXE1, BIOW_BACPZ ;  E8VHU4, BIOW_BACST ;
DR   P53559, BIOW_BACSU ;  Q6NGW9, BIOW_CORDI ;  D8KN09, BIOW_CORPF ;
DR   B8J3V1, BIOW_DESDA ;  C9RPK4, BIOW_FIBSS ;  D3DK66, BIOW_HYDTT ;
DR   P22822, BIOW_LYSSH ;  A6UWX4, BIOW_META3 ;  D5VQA3, BIOW_METIM ;
DR   Q58693, BIOW_METJA ;  A4FVV0, BIOW_METM5 ;  A9A986, BIOW_METM6 ;
DR   A6VHG3, BIOW_METM7 ;  Q6LWX9, BIOW_METMP ;  D3E0R7, BIOW_METRM ;
DR   D3S7P2, BIOW_METSF ;  C9REY1, BIOW_METVM ;  A6UQM0, BIOW_METVS ;
DR   Q3A3Z7, BIOW_PELCD ;  C0QSH0, BIOW_PERMH ;  A7X666, BIOW_STAA1 ;
DR   A6U4F3, BIOW_STAA2 ;  Q2FE74, BIOW_STAA3 ;  Q2FVJ9, BIOW_STAA8 ;
DR   A5IVK3, BIOW_STAA9 ;  Q2YVY8, BIOW_STAAB ;  Q5HDD1, BIOW_STAAC ;
DR   A6QJR2, BIOW_STAAE ;  P67549, BIOW_STAAM ;  P67550, BIOW_STAAN ;
DR   Q6GE10, BIOW_STAAR ;  Q6G6P8, BIOW_STAAS ;  Q8NV07, BIOW_STAAW ;
DR   Q5HKF3, BIOW_STAEQ ;  Q8CTZ3, BIOW_STAES ;  C1DW75, BIOW_SULAA ;
DR   B2V6W9, BIOW_SULSY ;  D3SN37, BIOW_THEAH ;  B5YK86, BIOW_THEYD ;
DR   D1BMT0, BIOW_VEIPT ;
//
ID   6.2.1.15
DE   Arachidonate--CoA ligase.
AN   Arachidonoyl-CoA synthetase.
CA   ATP + arachidonate + CoA = AMP + diphosphate + arachidonoyl-CoA.
CC   -!- 8,11,14-icosatrienoate, but not the other long-chain fatty acids,
CC       can act in place of arachidonate.
CC   -!- Not identical with EC 6.2.1.3.
//
ID   6.2.1.16
DE   Acetoacetate--CoA ligase.
AN   Acetoacetyl-CoA synthetase.
CA   ATP + acetoacetate + CoA = AMP + diphosphate + acetoacetyl-CoA.
CC   -!- Also acts, more slowly, on L-3-hydroxybutanoate.
PR   PROSITE; PDOC00427;
DR   Q5ZLG0, AACS_CHICK ;  A3QK15, AACS_DANRE ;  Q86V21, AACS_HUMAN ;
DR   Q9N0E1, AACS_MACFA ;  Q9D2R0, AACS_MOUSE ;  Q9JMI1, AACS_RAT   ;
DR   Q28BL6, AACS_XENTR ;  Q9Z3R3, ACSA1_RHIME;  Q21166, SUR5_CAEEL ;
//
ID   6.2.1.17
DE   Propionate--CoA ligase.
AN   Propionyl-CoA synthetase.
CA   ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA.
CC   -!- Propenoate can act instead of propanoate.
CC   -!- Not identical with EC 6.2.1.1 or EC 6.2.1.2.
DR   P77495, PRPE_ECOLI ;  P55912, PRPE_SALTY ;
//
ID   6.2.1.18
DE   Citrate--CoA ligase.
CA   ATP + citrate + CoA = ADP + phosphate + (3S)-citryl-CoA.
CC   -!- Component of EC 4.1.3.8.
//
ID   6.2.1.19
DE   Long-chain-fatty-acid--luciferin-component ligase.
AN   Acyl-protein synthetase.
CA   ATP + an acid + protein = AMP + diphosphate + an acyl-protein thioester.
CC   -!- Together with EC 1.2.1.50 forms a fatty acid reductase system which
CC       produces the substrate of EC 1.14.14.3, thus being a component of the
CC       bacterial luciferase system.
DR   P29334, LUXE_PHOLE ;  P19842, LUXE_PHOLU ;  P24272, LUXE_VIBFI ;
DR   P14286, LUXE_VIBHA ;
//
ID   6.2.1.20
DE   Long-chain-fatty-acid--[acyl-carrier-protein] ligase.
AN   Acyl-[acyl-carrier-protein] synthetase.
CA   ATP + an acid + [acyl-carrier-protein] = AMP + diphosphate + acyl-[acyl-
CA   carrier-protein].
CC   -!- Not identical with EC 6.2.1.3.
DR   A8AP56, AAS_CITK8  ;  A7ZQU2, AAS_ECO24  ;  B7UHQ4, AAS_ECO27  ;
DR   B7MLI2, AAS_ECO45  ;  B7LF13, AAS_ECO55  ;  Q8X6J8, AAS_ECO57  ;
DR   B5Z4F4, AAS_ECO5E  ;  B7NVY2, AAS_ECO7I  ;  C4ZZY9, AAS_ECOBW  ;
DR   B1XDP2, AAS_ECODH  ;  A8A3X0, AAS_ECOHS  ;  A1AF47, AAS_ECOK1  ;
DR   Q0TDZ6, AAS_ECOL5  ;  Q8FEA6, AAS_ECOL6  ;  B1IU08, AAS_ECOLC  ;
DR   P31119, AAS_ECOLI  ;  B7N768, AAS_ECOLU  ;  B6I6W1, AAS_ECOSE  ;
DR   B1LR34, AAS_ECOSM  ;  Q1R7H5, AAS_ECOUT  ;  A4WE11, AAS_ENT38  ;
DR   A7MR36, AAS_ENTS8  ;  Q6D107, AAS_ERWCT  ;  B2VFS7, AAS_ERWT9  ;
DR   B7LNJ2, AAS_ESCF3  ;  B5XUP2, AAS_KLEP3  ;  A6TDH2, AAS_KLEP7  ;
DR   C6DE43, AAS_PECCP  ;  Q7N7A9, AAS_PHOLL  ;  B5F4V4, AAS_SALA4  ;
DR   Q57KA7, AAS_SALCH  ;  B5FUB9, AAS_SALDC  ;  B5QWU2, AAS_SALEP  ;
DR   B5RDY6, AAS_SALG2  ;  B4TGR5, AAS_SALHS  ;  B4T503, AAS_SALNS  ;
DR   Q5PEN7, AAS_SALPA  ;  A9N3H8, AAS_SALPB  ;  C0PXJ8, AAS_SALPC  ;
DR   B5BFH6, AAS_SALPK  ;  B4TUM9, AAS_SALSV  ;  Q8Z406, AAS_SALTI  ;
DR   Q8ZMA4, AAS_SALTY  ;  B2TYQ5, AAS_SHIB3  ;  Q0T128, AAS_SHIF8  ;
DR   Q83JV7, AAS_SHIFL  ;  Q3YY21, AAS_SHISS  ;  A1JPF0, AAS_YERE8  ;
DR   A7FFD1, AAS_YERP3  ;  Q1CAS8, AAS_YERPA  ;  B2JZ75, AAS_YERPB  ;
DR   Q74RZ6, AAS_YERPE  ;  A9R2S1, AAS_YERPG  ;  A4TLD3, AAS_YERPP  ;
DR   Q667F1, AAS_YERPS  ;  B1JQC1, AAS_YERPY  ;  P0A4X9, MBTM_MYCBO ;
DR   Q73ZP7, MBTM_MYCPA ;  Q1BBA2, MBTM_MYCSS ;  P0A4X8, MBTM_MYCTU ;
//
ID   6.2.1.21
DE   Transferred entry: 6.2.1.30.
//
ID   6.2.1.22
DE   [Citrate (pro-3S)-lyase] ligase.
AN   Citrate lyase ligase.
AN   Citrate lyase synthetase.
CA   ATP + acetate + [citrate (pro-3S)-lyase](thiol form) = AMP + diphosphate
CA   + [citrate (pro-3S)-lyase](acetyl form).
CC   -!- Converts the inactive thiol form of EC 4.1.3.6 into the active form.
DR   P77390, CITC_ECOLI ;  P44462, CITC_HAEIN ;  P45410, CITC_KLEPN ;
DR   O53076, CITC_LEUMC ;
//
ID   6.2.1.23
DE   Dicarboxylate--CoA ligase.
CA   ATP + an alpha-omega-dicarboxylic acid + CoA = AMP + diphosphate +
CA   an omega-carboxyacyl-CoA.
CC   -!- Acts on dicarboxylic acids of chain length C(5) to C(16); the best
CC       substrate is dodecanedioic acid.
//
ID   6.2.1.24
DE   Phytanate--CoA ligase.
CA   ATP + phytanate + CoA = AMP + diphosphate + phytanoyl-CoA.
CC   -!- Not identical with EC 6.2.1.20.
//
ID   6.2.1.25
DE   Benzoate--CoA ligase.
CA   ATP + benzoate + CoA = AMP + diphosphate + benzoyl-CoA.
CC   -!- Also acts on 2-, 3- and 4-fluorobenzoate, but only very slowly on the
CC       corresponding chlorobenzoates.
DR   Q53005, 4HBCL_RHOPA;  Q8GQN9, BCLA_THAAR ;
//
ID   6.2.1.26
DE   o-succinylbenzoate--CoA ligase.
AN   o-succinylbenzoyl-CoA synthetase.
AN   OSB-CoA synthetase.
CA   ATP + 2-succinylbenzoate + CoA = AMP + diphosphate + 2-succinylbenzoyl-
CA   CoA.
PR   PROSITE; PDOC00427;
DR   Q8VYJ1, MENE_ARATH ;  A7Z809, MENE_BACA2 ;  C3PCK3, MENE_BACAA ;
DR   C3LB87, MENE_BACAC ;  A0RK73, MENE_BACAH ;  Q81K97, MENE_BACAN ;
DR   B7JDD6, MENE_BACC0 ;  Q72YK9, MENE_BACC1 ;  B7HTW3, MENE_BACC7 ;
DR   A7GU88, MENE_BACCN ;  B9J2F2, MENE_BACCQ ;  Q816I1, MENE_BACCR ;
DR   Q632I5, MENE_BACCZ ;  Q6HC29, MENE_BACHK ;  Q65FT5, MENE_BACLD ;
DR   A8FGK6, MENE_BACP2 ;  P23971, MENE_BACSU ;  A9VM74, MENE_BACWK ;
DR   P37353, MENE_ECOLI ;  Q838K1, MENE_ENTFA ;  Q5KVX9, MENE_GEOKA ;
DR   C5D6U5, MENE_GEOSW ;  P44565, MENE_HAEIN ;  Q9CHK3, MENE_LACLA ;
DR   Q92AY8, MENE_LISIN ;  Q71YZ5, MENE_LISMF ;  P58730, MENE_LISMO ;
DR   O06408, MENE_MYCTU ;  Q8ENZ7, MENE_OCEIH ;  P37418, MENE_SALTY ;
DR   A7X3P0, MENE_STAA1 ;  A6U2Q7, MENE_STAA2 ;  Q2FFU9, MENE_STAA3 ;
DR   Q2G2V3, MENE_STAA8 ;  A5ITW2, MENE_STAA9 ;  Q2YTP0, MENE_STAAB ;
DR   Q5HEY2, MENE_STAAC ;  A6QHX6, MENE_STAAE ;  P63525, MENE_STAAM ;
DR   P63526, MENE_STAAN ;  Q6GFR0, MENE_STAAR ;  Q6G8D6, MENE_STAAS ;
DR   A8Z4L9, MENE_STAAT ;  Q53634, MENE_STAAU ;  Q8NVZ4, MENE_STAAW ;
DR   Q5HNB2, MENE_STAEQ ;  Q8CS21, MENE_STAES ;
//
ID   6.2.1.27
DE   4-hydroxybenzoate--CoA ligase.
AN   4-hydroxybenzoate-CoA synthetase.
AN   4-hydroxybenzoyl-CoA ligase.
CA   ATP + 4-hydroxybenzoate + CoA = AMP + diphosphate + 4-hydroxybenzoyl-CoA.
DR   Q9AJS8, 3HBCL_THAAR;  Q53005, 4HBCL_RHOPA;
//
ID   6.2.1.28
DE   3-alpha,7-alpha-dihydroxy-5-beta-cholestanate--CoA ligase.
AN   DHCA-CoA ligase.
CA   ATP + 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate + CoA = AMP +
CA   diphosphate + 3-alpha,7-alpha-dihydroxy-5-beta-cholestanoyl-CoA.
//
ID   6.2.1.29
DE   Transferred entry: 6.2.1.7.
//
ID   6.2.1.30
DE   Phenylacetate--CoA ligase.
CA   ATP + phenylacetate + CoA = AMP + diphosphate + phenylacetyl-CoA.
CC   -!- Also acts, more slowly, on acetate, propanoate and butanoate, but not
CC       on hydroxy derivatives of phenylacetate and related compounds.
CC   -!- Formerly EC 6.2.1.21.
DR   P76085, PAAK_ECOLI ;
//
ID   6.2.1.31
DE   2-furoate--CoA ligase.
CA   ATP + 2-furoate + CoA = AMP + diphosphate + 2-furoyl-CoA.
//
ID   6.2.1.32
DE   Anthranilate--CoA ligase.
CA   ATP + anthranilate + CoA = AMP + diphosphate + anthranilyl-CoA.
//
ID   6.2.1.33
DE   4-chlorobenzoate--CoA ligase.
CA   4-chlorobenzoate + CoA + ATP = 4-chlorobenzoyl-CoA + AMP + diphosphate.
CF   Magnesium.
CC   -!- Part of the bacterial 2,4-dichlorobenzoate degradation pathway.
DR   A5JTM6, CBACL_PSEUC;  P86831, CBCL1_ARTSP;  P86832, CBCL2_ARTSP;
//
ID   6.2.1.34
DE   Trans-feruloyl-CoA synthase.
AN   Trans-feruloyl-CoA synthetase.
CA   Ferulic acid + CoA + ATP = feruloyl-CoA + products of ATP breakdown.
CF   Magnesium.
CC   -!- It has not yet been established whether AMP + diphosphate or ADP +
CC       phosphate are formed in this reaction.
//
ID   6.2.1.35
DE   ACP-SH:acetate ligase.
AN   [Acyl-carrier protein]:acetate ligase.
CA   ATP + acetate + an [acyl-carrier protein] = AMP + diphosphate +
CA   an acetyl-[acyl-carrier protein].
CC   -!- This enzyme, from the anaerobic bacterium Malonomonas rubra, is a
CC       component of the multienzyme complex EC 4.1.1.89.
CC   -!- The enzyme uses the energy from hydrolysis of ATP to convert the
CC       thiol group of the acyl-carrier-protein-bound 2'-(5-phosphoribosyl)-
CC       3'-dephospho-CoA prosthetic group into its acetyl thioester.
//
ID   6.2.1.36
DE   3-hydroxypropionyl-CoA synthase.
AN   3-hydroxypropionate--CoA ligase.
AN   3-hydroxypropionyl-CoA synthetase (AMP-forming).
CA   3-hydroxypropanoate + ATP + coenzyme A = 3-hydroxypropionyl-CoA + AMP +
CA   diphosphate.
CC   -!- Catalyzes a step in the 3-hydroxypropanoate/4-hydroxybutyrate cycle,
CC       an autotrophic CO(2) fixation pathway found in some thermoacidophilic
CC       archaea.
CC   -!- The enzymes from Metallosphaera sedula and Sulfolobus tokodaii can
CC       also use propanoate, acrylate, acetate, and butanoate as substrates,
CC       and are thus different from EC 6.2.1.17, which does not accept
CC       acetate or butanoate.
DR   A4YGR1, HPCAS_METS5;  Q973W5, HPCAS_SULTO;
//
ID   6.2.1.n1
DE   3-hydroxybenzoate--CoA ligase.
AN   3-hydroxybenzoate--coenzyme A ligase (AMP-forming).
AN   3-hydroxybenzoyl coenzyme A synthetase.
AN   3-hydroxybenzyl-CoA synthetase.
CA   ATP + 3-hydroxybenzoate + CoA = AMP + diphosphate + 3-hydroxybenzoyl-CoA.
CC   -!- The enzyme works equally well with 4-hydroxybenzoate but shows low
CC       activity toward benzoate, 4-aminobenzoate, 3-aminobenzoate,
CC       3-fluorobenzoate, 4-fluorobenzoate, 3-chlorobenzoate,
CC       and 4-chlorobenzoate.
CC   -!- There is no activity with 3,4-dihydroxybenzoate, 2,3-
CC       dihydroxybenzoate, and 2-hydroxybenzoate as substrates.
DR   Q9AJS8, 3HBCL_THAAR;
//
ID   6.3.1.1
DE   Aspartate--ammonia ligase.
AN   Asparagine synthetase.
CA   ATP + L-aspartate + NH(3) = AMP + diphosphate + L-asparagine.
DR   A3N3D3, ASNA_ACTP2 ;  B3GZ90, ASNA_ACTP7 ;  B0BT12, ASNA_ACTPJ ;
DR   A6VLN1, ASNA_ACTSZ ;  A4SHR6, ASNA_AERS4 ;  C3P6N8, ASNA_BACAA ;
DR   C3L6U1, ASNA_BACAC ;  A0RCH7, ASNA_BACAH ;  Q81S64, ASNA_BACAN ;
DR   B7JIX2, ASNA_BACC0 ;  P61397, ASNA_BACC1 ;  B7IRB0, ASNA_BACC2 ;
DR   C1EPH2, ASNA_BACC3 ;  B7HIG1, ASNA_BACC4 ;  B7HMI7, ASNA_BACC7 ;
DR   A7GNN8, ASNA_BACCN ;  B9IX36, ASNA_BACCQ ;  Q81F55, ASNA_BACCR ;
DR   Q63D03, ASNA_BACCZ ;  Q5L9E0, ASNA_BACFN ;  Q64PM4, ASNA_BACFR ;
DR   Q6HKD8, ASNA_BACHK ;  Q8A5V7, ASNA_BACTN ;  A9VPK1, ASNA_BACWK ;
DR   B8I6R1, ASNA_CLOCE ;  Q0TNY3, ASNA_CLOP1 ;  Q8XIY5, ASNA_CLOPE ;
DR   Q0SRK2, ASNA_CLOPS ;  Q897F7, ASNA_CLOTE ;  A7ZTV5, ASNA_ECO24 ;
DR   B7UMK9, ASNA_ECO27 ;  B7MGG4, ASNA_ECO45 ;  B7L891, ASNA_ECO55 ;
DR   P63624, ASNA_ECO57 ;  B5YY02, ASNA_ECO5E ;  B7NR46, ASNA_ECO7I ;
DR   B7N247, ASNA_ECO81 ;  B7M5A0, ASNA_ECO8A ;  C4ZZ22, ASNA_ECOBW ;
DR   B1X9X2, ASNA_ECODH ;  A8A6K7, ASNA_ECOHS ;  A1AHS4, ASNA_ECOK1 ;
DR   Q0TAW5, ASNA_ECOL5 ;  P63623, ASNA_ECOL6 ;  B1IWZ4, ASNA_ECOLC ;
DR   P00963, ASNA_ECOLI ;  B7NF60, ASNA_ECOLU ;  B6I3Y1, ASNA_ECOSE ;
DR   B1LL71, ASNA_ECOSM ;  Q1R4I8, ASNA_ECOUT ;  C5BDG9, ASNA_EDWI9 ;
DR   A4WGE3, ASNA_ENT38 ;  A7MMW6, ASNA_ENTS8 ;  Q6DB95, ASNA_ERWCT ;
DR   B7LK89, ASNA_ESCF3 ;  P58824, ASNA_FUSNN ;  Q7VKJ0, ASNA_HAEDU ;
DR   Q4QMY5, ASNA_HAEI8 ;  A5U9S9, ASNA_HAEIE ;  A5UH70, ASNA_HAEIG ;
DR   P44338, ASNA_HAEIN ;  B8F7Y7, ASNA_HAEPS ;  B0US32, ASNA_HAES2 ;
DR   B5XZL2, ASNA_KLEP3 ;  A6TG48, ASNA_KLEP7 ;  Q5FHY0, ASNA_LACAC ;
DR   Q03PZ8, ASNA_LACBA ;  P54264, ASNA_LACDA ;  Q04A69, ASNA_LACDB ;
DR   B2GE56, ASNA_LACF3 ;  A8YTK7, ASNA_LACH4 ;  P61190, ASNA_LACJO ;
DR   Q88Y39, ASNA_LACPL ;  A5VMP8, ASNA_LACRD ;  Q1WTD6, ASNA_LACS1 ;
DR   Q65WL7, ASNA_MANSM ;  Q7NAM0, ASNA_MYCGA ;  Q8EWQ5, ASNA_MYCPE ;
DR   A6LI95, ASNA_PARD8 ;  Q9CKN6, ASNA_PASMU ;  C6DJG0, ASNA_PECCP ;
DR   Q03E72, ASNA_PEDPA ;  Q7NA83, ASNA_PHOLL ;  B4F0D5, ASNA_PROMH ;
DR   B5EZ10, ASNA_SALA4 ;  Q57HW6, ASNA_SALCH ;  B5FN47, ASNA_SALDC ;
DR   B5QVE4, ASNA_SALEP ;  B4TAY6, ASNA_SALHS ;  B4SYE5, ASNA_SALNS ;
DR   Q5PJY0, ASNA_SALPA ;  A9MXC1, ASNA_SALPB ;  C0Q2P4, ASNA_SALPC ;
DR   B5BIP8, ASNA_SALPK ;  B4TN45, ASNA_SALSV ;  Q8Z2Q9, ASNA_SALTI ;
DR   Q8ZKW4, ASNA_SALTY ;  A8GLK7, ASNA_SERP5 ;  B2TUN1, ASNA_SHIB3 ;
DR   Q31UP3, ASNA_SHIBS ;  Q329T3, ASNA_SHIDS ;  Q0SYT2, ASNA_SHIF8 ;
DR   Q83PJ4, ASNA_SHIFL ;  Q3YVP8, ASNA_SHISS ;  Q3K2R9, ASNA_STRA1 ;
DR   Q8E6R5, ASNA_STRA3 ;  Q8E1B0, ASNA_STRA5 ;  C0MBY9, ASNA_STRE4 ;
DR   B4U1S6, ASNA_STREM ;  Q99YU0, ASNA_STRP1 ;  Q04IJ8, ASNA_STRP2 ;
DR   P0CZ84, ASNA_STRP3 ;  B5E2G2, ASNA_STRP4 ;  Q5XAY8, ASNA_STRP6 ;
DR   C1CA16, ASNA_STRP7 ;  P63626, ASNA_STRP8 ;  Q1JAR8, ASNA_STRPB ;
DR   Q1JKW9, ASNA_STRPC ;  Q1JFZ5, ASNA_STRPD ;  Q1J5R0, ASNA_STRPF ;
DR   A2RDJ5, ASNA_STRPG ;  B1I8S4, ASNA_STRPI ;  B8ZNX6, ASNA_STRPJ ;
DR   Q48SJ3, ASNA_STRPM ;  Q97NQ0, ASNA_STRPN ;  P0CZ85, ASNA_STRPQ ;
DR   B2IM49, ASNA_STRPS ;  B5XMB7, ASNA_STRPZ ;  Q8CWN8, ASNA_STRR6 ;
DR   C0MD73, ASNA_STRS7 ;  Q5M189, ASNA_STRT1 ;  Q5M5S6, ASNA_STRT2 ;
DR   Q03M60, ASNA_STRTD ;  B9DUY5, ASNA_STRU0 ;  C1CGQ3, ASNA_STRZJ ;
DR   C1CMR7, ASNA_STRZP ;  C1CTM5, ASNA_STRZT ;  O83567, ASNA_TREPA ;
DR   B2S3E8, ASNA_TREPS ;  B1AJ02, ASNA_UREP2 ;  Q9PQC8, ASNA_UREPA ;
DR   B5ZBH5, ASNA_UREU1 ;  A1JHR0, ASNA_YERE8 ;  A7FCM9, ASNA_YERP3 ;
DR   Q1CC50, ASNA_YERPA ;  B2K7I9, ASNA_YERPB ;  Q8ZJT3, ASNA_YERPE ;
DR   A9QYG3, ASNA_YERPG ;  Q1CNU4, ASNA_YERPN ;  A4TSI1, ASNA_YERPP ;
DR   Q66GH8, ASNA_YERPS ;  B1JR29, ASNA_YERPY ;
//
ID   6.3.1.2
DE   Glutamate--ammonia ligase.
AN   Glutamine synthetase.
CA   ATP + L-glutamate + NH(3) = ADP + phosphate + L-glutamine.
CC   -!- Also acts, more slowly, on 4-methylene-L-glutamate (cf. EC 6.3.1.7).
PR   PROSITE; PDOC00162;
DR   Q56WN1, GLN11_ARATH;  P14656, GLN11_ORYSJ;  Q8LCE1, GLN12_ARATH;
DR   P14654, GLN12_ORYSJ;  Q9LVI8, GLN13_ARATH;  Q4W8D0, GLN13_ORYSJ;
DR   Q9FMD9, GLN14_ARATH;  Q8GXW5, GLN15_ARATH;  O04867, GLNA1_ALNGL;
DR   P05457, GLNA1_BRAJA;  Q42688, GLNA1_CHLRE;  O22504, GLNA1_DAUCA;
DR   Q86B00, GLNA1_DICDI;  P20477, GLNA1_DROME;  P46033, GLNA1_FRAAL;
DR   Q42899, GLNA1_LOTJA;  P38559, GLNA1_MAIZE;  P04078, GLNA1_MEDSA;
DR   P0A591, GLNA1_MYCBO;  A0R079, GLNA1_MYCS2;  P0A590, GLNA1_MYCTU;
DR   P08282, GLNA1_PEA  ;  P04770, GLNA1_PHAVU;  P09826, GLNA1_RHILV;
DR   Q59747, GLNA1_RHIME;  P24099, GLNA1_SOYBN;  P77958, GLNA1_STRFL;
DR   Q05542, GLNA1_STRVR;  P51118, GLNA1_VITVI;  Q43127, GLNA2_ARATH;
DR   P04772, GLNA2_BRAJA;  Q42689, GLNA2_CHLRE;  O22506, GLNA2_DAUCA;
DR   P0C7B6, GLNA2_DICDI;  P20478, GLNA2_DROME;  P81643, GLNA2_EMIHU;
DR   P20805, GLNA2_FRAAL;  P13564, GLNA2_HORVU;  P38560, GLNA2_MAIZE;
DR   Q9XQ94, GLNA2_MEDSA;  P64246, GLNA2_MYCBO;  A0R083, GLNA2_MYCS2;
DR   P64245, GLNA2_MYCTU;  P14655, GLNA2_ORYSJ;  P08281, GLNA2_PEA  ;
DR   P04771, GLNA2_PHAVU;  P81107, GLNA2_PINPS;  Q02154, GLNA2_RHILP;
DR   P45626, GLNA2_RHIME;  O82560, GLNA2_SOYBN;  P22878, GLNA2_STRHY;
DR   P19432, GLNA2_STRVR;  P51119, GLNA2_VITVI;  Q54WR9, GLNA3_DICDI;
DR   Q06378, GLNA3_HORVU;  P14636, GLNA3_LUPAN;  P38561, GLNA3_MAIZE;
DR   Q43785, GLNA3_MEDSA;  P07694, GLNA3_PEA  ;  P00965, GLNA3_PHAVU;
DR   P31592, GLNA3_RHILP;  O87393, GLNA3_RHIME;  P38562, GLNA4_MAIZE;
DR   Q43066, GLNA4_PEA  ;  P15102, GLNA4_PHAVU;  P38563, GLNA5_MAIZE;
DR   Q42624, GLNAC_BRANA;  P25462, GLNAC_MAIZE;  Q9QY94, GLNA_ACOCA ;
DR   O00088, GLNA_AGABI ;  Q8X169, GLNA_AMAMU ;  O66514, GLNA_AQUAE ;
DR   O29313, GLNA_ARCFU ;  Q75BT9, GLNA_ASHGO ;  P10583, GLNA_AZOBR ;
DR   P94126, GLNA_AZOC5 ;  P22248, GLNA_AZOVI ;  P19064, GLNA_BACCE ;
DR   P15623, GLNA_BACFR ;  P12425, GLNA_BACSU ;  P15103, GLNA_BOVIN ;
DR   Q05650, GLNA_BUTFI ;  P34497, GLNA_CAEEL ;  Q8HZM5, GLNA_CANFA ;
DR   Q6FMT6, GLNA_CANGA ;  P16580, GLNA_CHICK ;  P10656, GLNA_CLOSA ;
DR   Q12613, GLNA_COLGL ;  P04773, GLNA_CRIGR ;  P0CN85, GLNA_CRYNB ;
DR   P0CN84, GLNA_CRYNJ ;  Q6B4U7, GLNA_DEBHA ;  P11600, GLNA_DUNSA ;
DR   P0A9C7, GLNA_ECO57 ;  P0A9C6, GLNA_ECOL6 ;  P0A9C5, GLNA_ECOLI ;
DR   Q96V52, GLNA_EMENI ;  P33035, GLNA_FREDI ;  Q9UUN6, GLNA_FUSSH ;
DR   Q9C2U9, GLNA_GIBFU ;  P43794, GLNA_HAEIN ;  Q9HNI2, GLNA_HALSA ;
DR   P43386, GLNA_HALVD ;  Q96UV5, GLNA_HEBCY ;  Q9ZLW5, GLNA_HELPJ ;
DR   P94845, GLNA_HELPY ;  P15104, GLNA_HUMAN ;  Q874T6, GLNA_KLULA ;
DR   P45627, GLNA_LACDE ;  Q9CDL9, GLNA_LACLA ;  P23712, GLNA_LACSA ;
DR   P52782, GLNA_LUPLU ;  Q4R7U3, GLNA_MACFA ;  P15124, GLNA_METCA ;
DR   Q60182, GLNA_METJA ;  O59648, GLNA_METMP ;  O27612, GLNA_METTH ;
DR   P21154, GLNA_METVO ;  Q5UR44, GLNA_MIMIV ;  P15105, GLNA_MOUSE ;
DR   P25821, GLNA_NEIGO ;  Q86ZF9, GLNA_NEUCR ;  P12424, GLNA_NICPL ;
DR   P00964, GLNA_NOSS1 ;  Q04831, GLNA_PANAR ;  Q9CLP2, GLNA_PASMU ;
DR   P20479, GLNA_PHOLP ;  P46410, GLNA_PIG   ;  P52783, GLNA_PINSY ;
DR   P28786, GLNA_PROHU ;  Q9HU65, GLNA_PSEAE ;  Q9UY99, GLNA_PYRAB ;
DR   Q05907, GLNA_PYRFU ;  O58097, GLNA_PYRHO ;  O08467, GLNA_PYRKO ;
DR   P36687, GLNA_PYRWO ;  P09606, GLNA_RAT   ;  P13499, GLNA_RHOCA ;
DR   P43518, GLNA_RHOSH ;  P0A1P7, GLNA_SALTI ;  P0A1P6, GLNA_SALTY ;
DR   Q09179, GLNA_SCHPO ;  P0A9C8, GLNA_SHIFL ;  P41320, GLNA_SQUAC ;
DR   Q5HGC3, GLNA_STAAC ;  P60890, GLNA_STAAM ;  P99095, GLNA_STAAN ;
DR   Q6GHC6, GLNA_STAAR ;  Q6G9Q4, GLNA_STAAS ;  P0A040, GLNA_STAAU ;
DR   P0A039, GLNA_STAAW ;  Q5HPN2, GLNA_STAEQ ;  Q8CSR8, GLNA_STAES ;
DR   P15106, GLNA_STRCO ;  Q8J1R3, GLNA_SUIBO ;  Q9HH09, GLNA_SULAC ;
DR   P23794, GLNA_SULSO ;  P28605, GLNA_SYNP2 ;  P77961, GLNA_SYNY3 ;
DR   P36205, GLNA_THEMA ;  P07804, GLNA_THIFE ;  P51120, GLNA_TRITH ;
DR   Q86ZU6, GLNA_TUBBO ;  P19904, GLNA_VIBAL ;  Q9KNJ2, GLNA_VIBCH ;
DR   P32289, GLNA_VIGAC ;  P85087, GLNA_VITSX ;  P51121, GLNA_XENLA ;
DR   Q6C3E0, GLNA_YARLI ;  P32288, GLNA_YEAST ;
//
ID   6.3.1.3
DE   Transferred entry: 6.3.4.13.
//
ID   6.3.1.4
DE   Aspartate--ammonia ligase (ADP-forming).
AN   Asparagine synthetase (ADP-forming).
CA   ATP + L-aspartate + NH(3) = ADP + phosphate + L-asparagine.
//
ID   6.3.1.5
DE   NAD(+) synthase.
AN   NAD(+) synthetase.
CA   ATP + deamido-NAD(+) + NH(3) = AMP + diphosphate + NAD(+).
CC   -!- L-glutamine also acts, more slowly, as amido-donor (cf. EC 6.3.5.1).
DR   Q9WZB3, NADE1_THEMA;  Q9YAI1, NADE_AERPE ;  B9JNG1, NADE_AGRRK ;
DR   B6ERM8, NADE_ALISL ;  A6TQC4, NADE_ALKMQ ;  A8MHN7, NADE_ALKOO ;
DR   O29262, NADE_ARCFU ;  A7Z159, NADE_BACA2 ;  C3P7H9, NADE_BACAA ;
DR   C3L5J1, NADE_BACAC ;  A0RCZ8, NADE_BACAH ;  Q81RP3, NADE_BACAN ;
DR   B7JKI8, NADE_BACC0 ;  Q739R5, NADE_BACC1 ;  B7ITB1, NADE_BACC2 ;
DR   C1ERC2, NADE_BACC3 ;  B7HJC1, NADE_BACC4 ;  B7HND7, NADE_BACC7 ;
DR   A7GNW5, NADE_BACCN ;  B9IXY1, NADE_BACCQ ;  Q81EI2, NADE_BACCR ;
DR   Q63CG2, NADE_BACCZ ;  Q9KAK2, NADE_BACHD ;  Q6HJW8, NADE_BACHK ;
DR   Q65NN6, NADE_BACLD ;  A8F9S0, NADE_BACP2 ;  P08164, NADE_BACSU ;
DR   A9VRQ8, NADE_BACWK ;  B8D8X4, NADE_BUCA5 ;  P57271, NADE_BUCAI ;
DR   Q8K9W7, NADE_BUCAP ;  B8D778, NADE_BUCAT ;  B1Z0R0, NADE_BURA4 ;
DR   Q1BQX0, NADE_BURCA ;  B1K5T6, NADE_BURCC ;  A0B2Y5, NADE_BURCH ;
DR   B4EIP2, NADE_BURCJ ;  A3MF00, NADE_BURM7 ;  A2RXU4, NADE_BURM9 ;
DR   Q62CU8, NADE_BURMA ;  A1UW43, NADE_BURMS ;  A3P6S9, NADE_BURP0 ;
DR   Q3JL79, NADE_BURP1 ;  B2TDV9, NADE_BURPP ;  Q63K83, NADE_BURPS ;
DR   Q39AM3, NADE_BURS3 ;  A7I243, NADE_CAMHC ;  A8FLM3, NADE_CAMJ8 ;
DR   A7H439, NADE_CAMJD ;  Q9PPB0, NADE_CAMJE ;  A1VZF8, NADE_CAMJJ ;
DR   Q5HUY2, NADE_CAMJR ;  Q3ABX6, NADE_CARHZ ;  B3QM51, NADE_CHLP8 ;
DR   B3ELE3, NADE_CHLPB ;  A1BEN4, NADE_CHLPD ;  Q8KEX2, NADE_CHLTE ;
DR   A8AHD1, NADE_CITK8 ;  B5Y8Q4, NADE_COPPD ;  Q8FMS2, NADE_COREF ;
DR   A4QGT5, NADE_CORGB ;  Q8NMN7, NADE_CORGL ;  Q1IYR1, NADE_DEIGD ;
DR   Q9RYV5, NADE_DEIRA ;  A7ZMK7, NADE_ECO24 ;  B7USC1, NADE_ECO27 ;
DR   B7MAV1, NADE_ECO45 ;  B7L6L4, NADE_ECO55 ;  Q8XDZ9, NADE_ECO57 ;
DR   B5YQ27, NADE_ECO5E ;  B7NT37, NADE_ECO7I ;  B7MVL9, NADE_ECO81 ;
DR   B7M1F2, NADE_ECO8A ;  C4ZZ96, NADE_ECOBW ;  B1XGK1, NADE_ECODH ;
DR   A8A0T1, NADE_ECOHS ;  A1ABS1, NADE_ECOK1 ;  Q0TH90, NADE_ECOL5 ;
DR   Q8FH06, NADE_ECOL6 ;  B1IPJ0, NADE_ECOLC ;  P18843, NADE_ECOLI ;
DR   B7N576, NADE_ECOLU ;  B6IBG0, NADE_ECOSE ;  B1LDZ1, NADE_ECOSM ;
DR   Q1RB54, NADE_ECOUT ;  A4W9K3, NADE_ENT38 ;  Q830Y9, NADE_ENTFA ;
DR   A7MNW9, NADE_ENTS8 ;  Q6D4H8, NADE_ERWCT ;  B2VEK0, NADE_ERWT9 ;
DR   B7LQ52, NADE_ESCF3 ;  B1YJ94, NADE_EXIS2 ;  C4L5A2, NADE_EXISA ;
DR   B0S1S2, NADE_FINM2 ;  Q8REA7, NADE_FUSNN ;  B3E4K8, NADE_GEOLS ;
DR   A5G7Y9, NADE_GEOUR ;  B0R6W9, NADE_HALS3 ;  Q9HNM7, NADE_HALSA ;
DR   Q17X65, NADE_HELAH ;  Q7VHF9, NADE_HELHP ;  B6JKQ6, NADE_HELP2 ;
DR   B5ZA97, NADE_HELPG ;  Q1CUH2, NADE_HELPH ;  Q9ZMB0, NADE_HELPJ ;
DR   B2USG0, NADE_HELPS ;  O25096, NADE_HELPY ;  A2BLB9, NADE_HYPBU ;
DR   Q03SX9, NADE_LACBA ;  Q037P8, NADE_LACC3 ;  B3W8T2, NADE_LACCB ;
DR   B2GA98, NADE_LACF3 ;  Q041J1, NADE_LACGA ;  Q74I36, NADE_LACJO ;
DR   Q9CGJ4, NADE_LACLA ;  A2RL82, NADE_LACLM ;  Q02Z86, NADE_LACLS ;
DR   Q88Z14, NADE_LACPL ;  A5VI81, NADE_LACRD ;  B2G5Q7, NADE_LACRJ ;
DR   Q1WSR2, NADE_LACS1 ;  Q38VA7, NADE_LACSS ;  Q6AER9, NADE_LEIXX ;
DR   Q92CU3, NADE_LISIN ;  C1L207, NADE_LISMC ;  Q720Y0, NADE_LISMF ;
DR   B8DCC1, NADE_LISMH ;  Q8Y825, NADE_LISMO ;  A0AHK4, NADE_LISW6 ;
DR   B1HTT1, NADE_LYSSC ;  Q65RB5, NADE_MANSM ;  Q6F0U4, NADE_MESFL ;
DR   A6UUS4, NADE_META3 ;  Q8TK88, NADE_METAC ;  A7IAS7, NADE_METB6 ;
DR   Q12V31, NADE_METBU ;  Q58747, NADE_METJA ;  Q8TVH1, NADE_METKA ;
DR   Q8PZP6, NADE_METMA ;  O27554, NADE_METTH ;  B1ME26, NADE_MYCA9 ;
DR   P47623, NADE_MYCGE ;  Q8EWK9, NADE_MYCPE ;  P75216, NADE_MYCPN ;
DR   Q98PU6, NADE_MYCPU ;  Q5YRN0, NADE_NOCFA ;  Q8ET75, NADE_OCEIH ;
DR   C6DFZ6, NADE_PECCP ;  Q3B5D4, NADE_PELLD ;  B4SEZ8, NADE_PELPB ;
DR   Q6LIU7, NADE_PHOPR ;  Q6L0D1, NADE_PICTO ;  A4SFG4, NADE_PROVI ;
DR   Q48NY2, NADE_PSE14 ;  A6VD32, NADE_PSEA7 ;  B7V1Y3, NADE_PSEA8 ;
DR   Q02F98, NADE_PSEAB ;  Q9HUP3, NADE_PSEAE ;  Q1I469, NADE_PSEE4 ;
DR   Q3IF87, NADE_PSEHT ;  A4XS59, NADE_PSEMY ;  A5W9Q7, NADE_PSEP1 ;
DR   Q3KIW5, NADE_PSEPF ;  B0KKX4, NADE_PSEPG ;  Q88DF6, NADE_PSEPK ;
DR   B1J649, NADE_PSEPW ;  Q87VL4, NADE_PSESM ;  Q4ZYV8, NADE_PSEU2 ;
DR   A4VKK4, NADE_PSEU5 ;  A1SZH7, NADE_PSYIN ;  Q9V2A9, NADE_PYRAB ;
DR   Q8ZXL4, NADE_PYRAE ;  Q8U4I9, NADE_PYRFU ;  O57921, NADE_PYRHO ;
DR   Q5JJ65, NADE_PYRKO ;  Q988H0, NADE_RHILO ;  Q92TY6, NADE_RHIME ;
DR   C0ZXG7, NADE_RHOE4 ;  C1B1N8, NADE_RHOOB ;  Q0S2M9, NADE_RHOSR ;
DR   B5F7I4, NADE_SALA4 ;  A9MFF4, NADE_SALAR ;  Q57PX4, NADE_SALCH ;
DR   B5FJD0, NADE_SALDC ;  B5QWI3, NADE_SALEP ;  B5RAZ4, NADE_SALG2 ;
DR   B4TGE8, NADE_SALHS ;  B4T4K7, NADE_SALNS ;  Q5PHB6, NADE_SALPA ;
DR   A9N269, NADE_SALPB ;  C0Q6X4, NADE_SALPC ;  B5BA65, NADE_SALPK ;
DR   B4TUC9, NADE_SALSV ;  Q8Z6G6, NADE_SALTI ;  Q8ZPU5, NADE_SALTY ;
DR   A1S5V3, NADE_SHEAM ;  B8E735, NADE_SHEB2 ;  A3D5M3, NADE_SHEB5 ;
DR   A6WPH7, NADE_SHEB8 ;  A9L564, NADE_SHEB9 ;  Q12PA8, NADE_SHEDO ;
DR   Q084C2, NADE_SHEFN ;  B0TK55, NADE_SHEHH ;  Q8EFF2, NADE_SHEON ;
DR   A8H3E4, NADE_SHEPA ;  A4Y7T2, NADE_SHEPC ;  B8CNP2, NADE_SHEPW ;
DR   A8FU90, NADE_SHESH ;  A1RIQ6, NADE_SHESW ;  B1KJ47, NADE_SHEWM ;
DR   B2U3C0, NADE_SHIB3 ;  Q321N2, NADE_SHIBS ;  Q32G79, NADE_SHIDS ;
DR   Q0T4U8, NADE_SHIF8 ;  Q83RG5, NADE_SHIFL ;  Q3Z287, NADE_SHISS ;
DR   Q2NRT4, NADE_SODGM ;  A7X442, NADE_STAA1 ;  A6U318, NADE_STAA2 ;
DR   Q2FFI3, NADE_STAA3 ;  Q2G236, NADE_STAA8 ;  A5IU80, NADE_STAA9 ;
DR   Q2YU60, NADE_STAAB ;  Q5HEK9, NADE_STAAC ;  A6QIE0, NADE_STAAE ;
DR   P65506, NADE_STAAM ;  P99150, NADE_STAAN ;  Q6GFE4, NADE_STAAR ;
DR   Q6G820, NADE_STAAS ;  A8Z2S7, NADE_STAAT ;  P65507, NADE_STAAW ;
DR   Q5HN23, NADE_STAEQ ;  Q8CNP1, NADE_STAES ;  Q4L7M6, NADE_STAHJ ;
DR   A3DP41, NADE_STAMF ;  Q49YV6, NADE_STAS1 ;  Q3K383, NADE_STRA1 ;
DR   Q8E771, NADE_STRA3 ;  Q8E1Q7, NADE_STRA5 ;  Q9RJM5, NADE_STRCO ;
DR   C0M795, NADE_STRE4 ;  B4U4I9, NADE_STREM ;  A8AVT9, NADE_STRGC ;
DR   Q8CWY4, NADE_STRMU ;  Q99YK9, NADE_STRP1 ;  Q04JT1, NADE_STRP2 ;
DR   P0DC64, NADE_STRP3 ;  B5E5S7, NADE_STRP4 ;  Q5XAM5, NADE_STRP6 ;
DR   C1C818, NADE_STRP7 ;  Q8NZY8, NADE_STRP8 ;  Q1JFM0, NADE_STRPD ;
DR   A2RD51, NADE_STRPG ;  B1ICL9, NADE_STRPI ;  B8ZKX7, NADE_STRPJ ;
DR   P65508, NADE_STRPN ;  P0DC65, NADE_STRPQ ;  B2IQN8, NADE_STRPS ;
DR   P65509, NADE_STRR6 ;  A4W3A3, NADE_STRS2 ;  C0MGX1, NADE_STRS7 ;
DR   A3CPY9, NADE_STRSV ;  A4VX00, NADE_STRSY ;  Q5M1L1, NADE_STRT1 ;
DR   Q5M652, NADE_STRT2 ;  Q03MI7, NADE_STRTD ;  B9DV66, NADE_STRU0 ;
DR   C1CF07, NADE_STRZJ ;  C1CLC7, NADE_STRZP ;  C1CQT7, NADE_STRZT ;
DR   Q4JCP0, NADE_SULAC ;  Q97WN9, NADE_SULSO ;  Q96YL5, NADE_SULTO ;
DR   Q0AX10, NADE_SYNWW ;  Q9HJR8, NADE_THEAC ;  B9KAZ2, NADE_THENN ;
DR   C6A5B5, NADE_THESM ;  Q979W4, NADE_THEVO ;  Q83HW8, NADE_TROW8 ;
DR   Q83GA8, NADE_TROWT ;  A5EYT7, NADE_VIBC3 ;  Q9KMW1, NADE_VIBCH ;
DR   C3LUM7, NADE_VIBCM ;  Q5DZX4, NADE_VIBF1 ;  B5ETZ2, NADE_VIBFM ;
DR   A7N654, NADE_VIBHB ;  Q87J41, NADE_VIBPA ;  B7VQP3, NADE_VIBSL ;
DR   Q8D3T7, NADE_VIBVU ;  Q7MFB0, NADE_VIBVY ;  Q7MAJ5, NADE_WOLSU ;
//
ID   6.3.1.6
DE   Glutamate--ethylamine ligase.
AN   N(5)-ethyl-L-glutamine synthetase.
AN   Theanine synthetase.
CA   ATP + L-glutamate + ethylamine = ADP + phosphate + N(5)-ethyl-L-
CA   glutamine.
//
ID   6.3.1.7
DE   4-methyleneglutamate--ammonia ligase.
AN   4-methyleneglutamine synthetase.
CA   ATP + 4-methylene-L-glutamate + NH(3) = AMP + diphosphate + 4-methylene-
CA   L-glutamine.
CC   -!- Glutamine can act instead of NH(3), more slowly.
//
ID   6.3.1.8
DE   Glutathionylspermidine synthase.
AN   Gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming).
AN   Glutathione:spermidine ligase (ADP-forming).
AN   Glutathionylspermidine synthetase.
AN   GSP synthetase.
CA   Gamma-L-glutamyl-L-cysteinyl-glycine + spermidine + ATP = N(1)-(gamma-L-
CA   glutamyl-L-cysteinyl-glycyl)-spermidine + ADP + phosphate.
CF   Magnesium.
CC   -!- Involved in the synthesis of trypanothione in trypanosomatids.
CC   -!- The enzyme from Escherichia coli is bifunctional and also catalyzes
CC       the EC 3.5.1.78 reaction, resulting in a net hydrolysis of ATP.
DR   P90518, GSP_CRIFA  ;  P0AES0, GSP_ECOLI  ;  P0AES1, GSP_SHIFL  ;
DR   Q9GT49, TRYS_TRYCR ;
//
ID   6.3.1.9
DE   Trypanothione synthase.
AN   TSR synthetase.
CA   Gamma-L-glutamyl-L-cysteinyl-glycine + N(1)-(gamma-L-glutamyl-L-
CA   cysteinyl-glycyl)-spermidine + ATP = N(1),N(8)-bis-(gamma-L-glutamyl-L-
CA   cysteinyl-glycyl)-spermidine + ADP + phosphate.
CF   Magnesium.
CC   -!- Involved in the synthesis of trypanothione in trypanosomatids.
PR   PROSITE; PDOC50975;
DR   O60993, TRYS_CRIFA ;  Q9GT49, TRYS_TRYCR ;
//
ID   6.3.1.10
DE   Adenosylcobinamide-phosphate synthase.
CA   (1) ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP +
CA   phosphate + adenosylcobinamide phosphate.
CA   (2) ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol = ADP + phosphate
CA   + adenosylcobinamide.
CC   -!- This enzyme forms part of the anaerobic cobalamin biosynthesis
CC       pathway.
CC   -!- One of the substrates for this reaction, (R)-1-aminopropan-2-yl
CC       phosphate, is produced by CobD (EC 4.1.1.81).
//
ID   6.3.1.11
DE   Glutamate--putrescine ligase.
AN   Gamma-glutamylputrescine synthetase.
CA   ATP + L-glutamate + putrescine = ADP + phosphate + gamma-L-
CA   glutamylputrescine.
CC   -!- Forms part of a bacterial putrescine utilization pathway.
PR   PROSITE; PDOC00162;
DR   P78061, PUUA_ECOLI ;
//
ID   6.3.1.12
DE   D-aspartate ligase.
AN   Asl(fm).
AN   D-aspartic acid-activating enzyme.
CA   ATP + D-aspartate + (beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-
CA   Lys-D-Ala-D-Ala))(n) = (beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-
CA   6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala))(n) + ADP + phosphate.
CC   -!- Forms part of the peptidoglycan assembly pathway of Gram-positive
CC       bacteria grown in medium containing D-Asp.
CC   -!- Normally, the side chains the acylate the 6-amino group of the
CC       L-lysine residue contain L-Ala-L-Ala but these amino acids are
CC       replaced by D-Asp when D-Asp is included in the medium.
CC   -!- Hybrid chains containing L-Ala-D-Asp, L-Ala-L-Ala-D-Asp or D-Asp-L-
CC       Ala are not formed.
CC   -!- Highly specific for D-aspartate, as L-aspartate, D-glutamate,
CC       D-alanine, D-iso-asparagine and D-malic acid are not substrates.
CC   -!- In Enterococcus faecium, the substrate D-aspartate is produced by
CC       EC 5.1.1.13.
PR   PROSITE; PDOC50975;
//
ID   6.3.1.13
DE   L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside
DE   ligase.
AN   MshC ligase.
AN   Mycothiol ligase.
CA   1-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + L-cysteine
CA   + ATP = 1-O-(2-(L-cysteinamido)-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-
CA   inositol + AMP + diphosphate.
CC   -!- This enzyme is a key enzyme in the biosynthesis of mycothiol, a small
CC       molecular weight thiol found in Mycobacteria spp. and other
CC       actinomycetes.
CC   -!- Mycothiol plays a fundamental role in these organisms by helping to
CC       provide protection from the effects of reactive oxygen species and
CC       electrophiles, including many antibiotics.
CC   -!- The enzyme may represent a novel target for new classes of
CC       antituberculars.
CC   -!- Formerly EC 6.1.1.n1.
DR   Q4JXD7, MSHC1_CORJK;  B1VEQ2, MSHC1_CORU7;  Q4JVN7, MSHC2_CORJK;
DR   B1VDU4, MSHC2_CORU7;  A0LU34, MSHC_ACIC1 ;  C6WIA0, MSHC_ACTMD ;
DR   A1R6P9, MSHC_ARTAT ;  B8H8K8, MSHC_ARTCA ;  A0JWX8, MSHC_ARTS2 ;
DR   C5BVB1, MSHC_BEUC1 ;  C7MCZ4, MSHC_BRAFD ;  C7Q9B2, MSHC_CATAD ;
DR   D5UFA8, MSHC_CELFN ;  A5CRN7, MSHC_CLAM3 ;  B0RC50, MSHC_CLAMS ;
DR   C3PG89, MSHC_CORA7 ;  Q6NH81, MSHC_CORDI ;  Q8FTD0, MSHC_COREF ;
DR   A4QEA0, MSHC_CORGB ;  Q8NQC4, MSHC_CORGL ;  C4LIL9, MSHC_CORK4 ;
DR   Q9FB57, MSHC_CORST ;  Q0RLV2, MSHC_FRAAA ;  Q2J9N8, MSHC_FRASC ;
DR   A8LH67, MSHC_FRASN ;  D2S6C9, MSHC_GEOOG ;  D0LDR0, MSHC_GORB4 ;
DR   C7R3Z4, MSHC_JONDD ;  A6W933, MSHC_KINRD ;  B2GIP6, MSHC_KOCRD ;
DR   D2PPT3, MSHC_KRIFD ;  C7NHQ9, MSHC_KYTSD ;  C5CBT9, MSHC_MICLC ;
DR   A0QF76, MSHC_MYCA1 ;  B1MPE6, MSHC_MYCA9 ;  P67018, MSHC_MYCBO ;
DR   A1KKH3, MSHC_MYCBP ;  C1AQ46, MSHC_MYCBT ;  A4TB85, MSHC_MYCGI ;
DR   B8ZRD9, MSHC_MYCLB ;  Q49784, MSHC_MYCLE ;  B2HFY1, MSHC_MYCMM ;
DR   Q73YS9, MSHC_MYCPA ;  A0QZY0, MSHC_MYCS2 ;  A3Q1B7, MSHC_MYCSJ ;
DR   A1UHV1, MSHC_MYCSK ;  Q1B774, MSHC_MYCSS ;  A5U4F6, MSHC_MYCTA ;
DR   A5WPA3, MSHC_MYCTF ;  C6DPT0, MSHC_MYCTK ;  P67017, MSHC_MYCTU ;
DR   A0PQV5, MSHC_MYCUA ;  A1TAS3, MSHC_MYCVP ;  C8X8S1, MSHC_NAKMY ;
DR   D7B412, MSHC_NOCDD ;  Q5YVL0, MSHC_NOCFA ;  A1SJZ6, MSHC_NOCSJ ;
DR   A9WSI9, MSHC_RENSM ;  C0ZZW9, MSHC_RHOE4 ;  C1ASS8, MSHC_RHOOB ;
DR   Q0SIC6, MSHC_RHOSR ;  D2NT85, MSHC_ROTMD ;  A4FBV6, MSHC_SACEN ;
DR   C7MWX8, MSHC_SACVD ;  A8M264, MSHC_SALAI ;  A4X6W9, MSHC_SALTO ;
DR   D1BHU9, MSHC_SANKS ;  D6ZFG9, MSHC_SEGRD ;  D3Q598, MSHC_STANL ;
DR   Q828M2, MSHC_STRAW ;  D7BSS4, MSHC_STRBB ;  Q9ADA4, MSHC_STRCO ;
DR   B1W2Y7, MSHC_STRGG ;  D2AU10, MSHC_STRRD ;  C9Z2Z3, MSHC_STRSW ;
DR   D6Y1N8, MSHC_THEBD ;  D1A2Q5, MSHC_THECD ;  Q47NV4, MSHC_THEFY ;
DR   D5UPJ5, MSHC_TSUPD ;  D1BS17, MSHC_XYLCX ;
//
ID   6.3.1.14
DE   Diphthine--ammonia ligase.
AN   Diphthamide synthase.
AN   Diphthamide synthetase.
CA   ATP + diphthine + NH(3) = ADP + phosphate + diphthamide.
CC   -!- This amidase catalyzes the last step in the conversion of an
CC       L-histidine residue in the translation elongation factor eEF-2 to
CC       diphthamide.
CC   -!- This factor is found in all archaebacteria and eukaryotes, but not in
CC       eubacteria, and is the target of bacterial toxins such as the
CC       diphtheria toxin and the Pseudomonas exotoxin A (see EC 2.4.2.36).
CC   -!- The substrate of the enzyme, diphthine, is produced by EC 2.1.1.98.
CC   -!- The nature of the ammonia donor is not known.
CC   -!- Formerly EC 6.3.2.22.
//
ID   6.3.2.1
DE   Pantoate--beta-alanine ligase.
AN   Pantoate-activating enzyme.
AN   Pantoic-activating enzyme.
AN   Pantothenate synthetase.
CA   ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate.
DR   Q9AMR9, PANC1_BRAJA;  Q0RK33, PANC1_FRAAA;  Q89JV7, PANC2_BRAJA;
DR   Q0REL2, PANC2_FRAAA;  Q0RC35, PANC3_FRAAA;  Q0RB94, PANC4_FRAAA;
DR   B0C6S1, PANCY_ACAM1;  Q3MEJ8, PANCY_ANAVT;  Q7NJM6, PANCY_GLOVI;
DR   Q8YSZ3, PANCY_NOSS1;  A3PF80, PANCY_PROM0;  A2C536, PANCY_PROM1;
DR   A8G795, PANCY_PROM2;  A2CBX2, PANCY_PROM3;  Q318F2, PANCY_PROM9;
DR   Q7V9S8, PANCY_PROMA;  Q7V583, PANCY_PROMM;  Q7UZR6, PANCY_PROMP;
DR   A2BTH1, PANCY_PROMS;  Q46IM3, PANCY_PROMT;  Q31P38, PANCY_SYNE7;
DR   Q2JRH9, PANCY_SYNJA;  Q2JJ30, PANCY_SYNJB;  Q5N530, PANCY_SYNP6;
DR   A5GIY5, PANCY_SYNPW;  Q7U4P0, PANCY_SYNPX;  A5GVR3, PANCY_SYNR3;
DR   Q0ICW2, PANCY_SYNS3;  Q3AUV1, PANCY_SYNS9;  Q3AMJ0, PANCY_SYNSC;
DR   Q55074, PANCY_SYNY3;  Q8DG73, PANCY_THEEB;  Q110U9, PANCY_TRIEI;
DR   A1TTW0, PANC_ACIAC ;  Q6F855, PANC_ACIAD ;  B7H010, PANC_ACIB3 ;
DR   B7I683, PANC_ACIB5 ;  B2HTG5, PANC_ACIBC ;  Q1IHA8, PANC_ACIBL ;
DR   B0VKK3, PANC_ACIBS ;  A3M294, PANC_ACIBT ;  B0V5P7, PANC_ACIBY ;
DR   A0LRC5, PANC_ACIC1 ;  C1F8U3, PANC_ACIC5 ;  A5FVZ7, PANC_ACICJ ;
DR   B9MEY7, PANC_ACIET ;  B7JBM7, PANC_ACIF2 ;  B5ES06, PANC_ACIF5 ;
DR   A1WBI8, PANC_ACISJ ;  A0KP08, PANC_AERHH ;  A4SJ60, PANC_AERS4 ;
DR   B9JH26, PANC_AGRRK ;  Q8UA92, PANC_AGRT5 ;  B9JXS2, PANC_AGRVS ;
DR   B2UND0, PANC_AKKM8 ;  Q0VSR4, PANC_ALCBS ;  Q0AB68, PANC_ALHEH ;
DR   B6ELE2, PANC_ALISL ;  B4RYN9, PANC_ALTMD ;  Q2IFU3, PANC_ANADE ;
DR   Q5P9T3, PANC_ANAMM ;  B9ML77, PANC_ANATD ;  O67891, PANC_AQUAE ;
DR   Q9FKB3, PANC_ARATH ;  A8ERB8, PANC_ARCB4 ;  Q5NXQ2, PANC_AROAE ;
DR   A1R163, PANC_ARTAT ;  A0JR91, PANC_ARTS2 ;  B6YS28, PANC_AZOPC ;
DR   A1KAA6, PANC_AZOSB ;  C1DFJ9, PANC_AZOVD ;  A7Z5Z3, PANC_BACA2 ;
DR   C3P5R0, PANC_BACAA ;  C3L8P9, PANC_BACAC ;  A0RBZ3, PANC_BACAH ;
DR   Q81ST2, PANC_BACAN ;  B7JHQ7, PANC_BACC0 ;  Q73AV3, PANC_BACC1 ;
DR   B7IPB8, PANC_BACC2 ;  C1EN37, PANC_BACC3 ;  B7HHU4, PANC_BACC4 ;
DR   B7HL54, PANC_BACC7 ;  A7GN77, PANC_BACCN ;  B9IVR2, PANC_BACCQ ;
DR   Q81FN6, PANC_BACCR ;  Q63DJ2, PANC_BACCZ ;  Q5LGS1, PANC_BACFN ;
DR   Q64XM3, PANC_BACFR ;  Q9KC86, PANC_BACHD ;  Q6HL15, PANC_BACHK ;
DR   Q65I57, PANC_BACLD ;  A8FEH6, PANC_BACP2 ;  Q5WGA4, PANC_BACSK ;
DR   P52998, PANC_BACSU ;  Q89ZR8, PANC_BACTN ;  A6L4C3, PANC_BACV8 ;
DR   A9VMF0, PANC_BACWK ;  A1US39, PANC_BARBK ;  Q6G456, PANC_BARHE ;
DR   Q6G079, PANC_BARQU ;  A9IRN9, PANC_BART1 ;  Q1LTN0, PANC_BAUCH ;
DR   Q6MHI2, PANC_BDEBA ;  Q2KUK2, PANC_BORA1 ;  Q7WF42, PANC_BORBR ;
DR   Q7W3R4, PANC_BORPA ;  A9I1G8, PANC_BORPD ;  Q7VSV1, PANC_BORPE ;
DR   A5EKW3, PANC_BRASB ;  B2S9H8, PANC_BRUA1 ;  Q2YPI2, PANC_BRUA2 ;
DR   Q57F30, PANC_BRUAB ;  A9M8B2, PANC_BRUC2 ;  C0RH45, PANC_BRUMB ;
DR   Q8YFC9, PANC_BRUME ;  A5VNS0, PANC_BRUO2 ;  B0CJW0, PANC_BRUSI ;
DR   Q8G2J0, PANC_BRUSU ;  B8D8Z5, PANC_BUCA5 ;  P57292, PANC_BUCAI ;
DR   Q8K9U7, PANC_BUCAP ;  B8D7A0, PANC_BUCAT ;  B1YUT9, PANC_BURA4 ;
DR   Q1BUH1, PANC_BURCA ;  B1JWS8, PANC_BURCC ;  A0K9L5, PANC_BURCH ;
DR   B4E8E5, PANC_BURCJ ;  Q0BCS8, PANC_BURCM ;  A9AHJ3, PANC_BURM1 ;
DR   A3MLN2, PANC_BURM7 ;  A2SAF0, PANC_BURM9 ;  Q62LE7, PANC_BURMA ;
DR   A1V5W8, PANC_BURMS ;  A3NSK8, PANC_BURP0 ;  Q3JUY8, PANC_BURP1 ;
DR   A3N6X2, PANC_BURP6 ;  B2JEQ7, PANC_BURP8 ;  B2T172, PANC_BURPP ;
DR   Q63W97, PANC_BURPS ;  Q39DU9, PANC_BURS3 ;  Q2T095, PANC_BURTA ;
DR   A4JGX1, PANC_BURVG ;  Q143J2, PANC_BURXL ;  A4XMZ3, PANC_CALS8 ;
DR   A7ZE20, PANC_CAMC1 ;  A7GZE9, PANC_CAMC5 ;  A0RQM8, PANC_CAMFF ;
DR   A7I0P8, PANC_CAMHC ;  A8FK86, PANC_CAMJ8 ;  A7H575, PANC_CAMJD ;
DR   Q9PIK2, PANC_CAMJE ;  A1VY17, PANC_CAMJJ ;  Q5HWH4, PANC_CAMJR ;
DR   Q3A9L1, PANC_CARHZ ;  Q9A6C8, PANC_CAUCR ;  B3PCR5, PANC_CELJU ;
DR   A9WFR6, PANC_CHLAA ;  B8G643, PANC_CHLAD ;  Q3APW7, PANC_CHLCH ;
DR   B3EH07, PANC_CHLL2 ;  B3QM10, PANC_CHLP8 ;  B3EMN7, PANC_CHLPB ;
DR   A1BDY2, PANC_CHLPD ;  B9LIH9, PANC_CHLSY ;  B3QSB4, PANC_CHLT3 ;
DR   Q8KBY5, PANC_CHLTE ;  Q1QSZ8, PANC_CHRSD ;  Q7NXJ0, PANC_CHRVO ;
DR   Q97F38, PANC_CLOAB ;  A7FR59, PANC_CLOB1 ;  C3L034, PANC_CLOB6 ;
DR   C1FS96, PANC_CLOBJ ;  B1IEL5, PANC_CLOBK ;  A7GAI5, PANC_CLOBL ;
DR   B1KUY6, PANC_CLOBM ;  B8I2Z3, PANC_CLOCE ;  Q18C33, PANC_CLOD6 ;
DR   A0PXQ4, PANC_CLONN ;  A3DDV6, PANC_CLOTH ;  Q47W59, PANC_COLP3 ;
DR   B5Y863, PANC_COPPD ;  Q6NEB8, PANC_CORDI ;  Q8FUA6, PANC_COREF ;
DR   A4QAA5, PANC_CORGB ;  Q9X713, PANC_CORGL ;  Q4JXL9, PANC_CORJK ;
DR   B6J9H9, PANC_COXB1 ;  B6J1Q4, PANC_COXB2 ;  A9KEG8, PANC_COXBN ;
DR   A9NBP1, PANC_COXBR ;  Q83EA3, PANC_COXBU ;  Q0K7I6, PANC_CUPNH ;
DR   Q474Y3, PANC_CUPPJ ;  B3R684, PANC_CUPTR ;  Q11NE6, PANC_CYTH3 ;
DR   Q47B65, PANC_DECAR ;  Q3Z8B3, PANC_DEHE1 ;  A5FR69, PANC_DEHSB ;
DR   Q3ZXF9, PANC_DEHSC ;  Q1J0L2, PANC_DEIGD ;  Q9RV66, PANC_DEIRA ;
DR   A9BV01, PANC_DELAS ;  B8FJ17, PANC_DESAA ;  C6C1U6, PANC_DESAD ;
DR   C0QHN3, PANC_DESAH ;  B8J4Q1, PANC_DESDA ;  Q311U9, PANC_DESDG ;
DR   B8FZE0, PANC_DESHD ;  Q251P2, PANC_DESHY ;  C4XPZ7, PANC_DESMR ;
DR   Q6ALV3, PANC_DESPS ;  Q729A4, PANC_DESVH ;  B8DSC4, PANC_DESVM ;
DR   A1VBJ2, PANC_DESVV ;  Q54I80, PANC_DICDI ;  A8LKA2, PANC_DINSH ;
DR   A7ZHM3, PANC_ECO24 ;  B7UII1, PANC_ECO27 ;  B7MBB6, PANC_ECO45 ;
DR   B7LGJ5, PANC_ECO55 ;  Q8X930, PANC_ECO57 ;  B5YZH0, PANC_ECO5E ;
DR   B7NI93, PANC_ECO7I ;  B7MNZ5, PANC_ECO81 ;  B7M174, PANC_ECO8A ;
DR   C4ZRM6, PANC_ECOBW ;  B1XCA8, PANC_ECODH ;  A7ZW82, PANC_ECOHS ;
DR   A1A7H9, PANC_ECOK1 ;  Q0TLJ9, PANC_ECOL5 ;  Q8FL31, PANC_ECOL6 ;
DR   B1IQK7, PANC_ECOLC ;  P31663, PANC_ECOLI ;  B7N803, PANC_ECOLU ;
DR   B6HZA8, PANC_ECOSE ;  B1LGT5, PANC_ECOSM ;  Q1RG57, PANC_ECOUT ;
DR   C5B9K5, PANC_EDWI9 ;  A4W6N7, PANC_ENT38 ;  Q833S6, PANC_ENTFA ;
DR   A7MGP7, PANC_ENTS8 ;  Q6D1X5, PANC_ERWCT ;  B2VD18, PANC_ERWT9 ;
DR   Q2N659, PANC_ERYLH ;  B7LW40, PANC_ESCF3 ;  B1YHQ8, PANC_EXIS2 ;
DR   C4L6Q1, PANC_EXISA ;  A7HND1, PANC_FERNB ;  A6GVV3, PANC_FLAPJ ;
DR   B0TXZ9, PANC_FRAP2 ;  Q14GL0, PANC_FRAT1 ;  A7NB31, PANC_FRATF ;
DR   Q2A4C7, PANC_FRATH ;  B2SFS8, PANC_FRATM ;  A0Q7L3, PANC_FRATN ;
DR   Q0BMQ6, PANC_FRATO ;  Q5NF57, PANC_FRATT ;  A4IWW5, PANC_FRATW ;
DR   B5E845, PANC_GEOBB ;  Q5KXX3, PANC_GEOKA ;  B3E5L0, PANC_GEOLS ;
DR   Q39V50, PANC_GEOMG ;  B9M2A2, PANC_GEOSF ;  Q74CG7, PANC_GEOSL ;
DR   C6E3N5, PANC_GEOSM ;  C5D3B2, PANC_GEOSW ;  A4IQ60, PANC_GEOTN ;
DR   A5G3A1, PANC_GEOUR ;  Q5FQ88, PANC_GLUOX ;  Q0BU46, PANC_GRABC ;
DR   A0M787, PANC_GRAFK ;  Q2S8W2, PANC_HAHCH ;  A1WUU4, PANC_HALHL ;
DR   Q17Z21, PANC_HELAH ;  Q7VK57, PANC_HELHP ;  B0TBP5, PANC_HELMI ;
DR   B6JPA5, PANC_HELP2 ;  B5Z6E3, PANC_HELPG ;  Q1CVE9, PANC_HELPH ;
DR   Q9ZN52, PANC_HELPJ ;  B2UW10, PANC_HELPS ;  P56061, PANC_HELPY ;
DR   A9B3W0, PANC_HERA2 ;  A4G3S0, PANC_HERAR ;  Q0C347, PANC_HYPNA ;
DR   Q5QVR4, PANC_IDILO ;  A6SWZ8, PANC_JANMA ;  B5Y1P6, PANC_KLEP3 ;
DR   A6T4S9, PANC_KLEP7 ;  C1D7E9, PANC_LARHH ;  Q5X1M7, PANC_LEGPA ;
DR   A5IAR4, PANC_LEGPC ;  Q5ZS57, PANC_LEGPH ;  Q5WTD6, PANC_LEGPL ;
DR   Q6ACQ8, PANC_LEIXX ;  B0S9F1, PANC_LEPBA ;  Q04S98, PANC_LEPBJ ;
DR   Q050C4, PANC_LEPBL ;  B0SS40, PANC_LEPBP ;  B1Y4K7, PANC_LEPCP ;
DR   Q72SD0, PANC_LEPIC ;  Q8F394, PANC_LEPIN ;  Q92AA7, PANC_LISIN ;
DR   C1KWK1, PANC_LISMC ;  Q71YB4, PANC_LISMF ;  B8DC25, PANC_LISMH ;
DR   Q8Y602, PANC_LISMO ;  A0AK06, PANC_LISW6 ;  O24035, PANC_LOTJA ;
DR   B1HU20, PANC_LYSSC ;  Q2VZ00, PANC_MAGSA ;  A0L3M5, PANC_MAGSM ;
DR   A1TYE5, PANC_MARAV ;  Q0ANX4, PANC_MARMM ;  A6W2I4, PANC_MARMS ;
DR   Q11F81, PANC_MESSB ;  Q605G9, PANC_METCA ;  Q1H3S1, PANC_METFK ;
DR   A2SEX7, PANC_METPP ;  Q2RM60, PANC_MOOTA ;  A0QA93, PANC_MYCA1 ;
DR   P0A5R1, PANC_MYCBO ;  A1KPT7, PANC_MYCBP ;  O69524, PANC_MYCLE ;
DR   Q743Y5, PANC_MYCPA ;  A0R580, PANC_MYCS2 ;  A3Q6Y5, PANC_MYCSJ ;
DR   A1UMI0, PANC_MYCSK ;  Q1B2L8, PANC_MYCSS ;  A5U8S7, PANC_MYCTA ;
DR   P0A5R0, PANC_MYCTU ;  A0PV50, PANC_MYCUA ;  A1TG35, PANC_MYCVP ;
DR   Q1DAN8, PANC_MYXXD ;  B9L5Y8, PANC_NAUPA ;  Q5F9F8, PANC_NEIG1 ;
DR   P57035, PANC_NEIMA ;  P57036, PANC_NEIMB ;  A1KTB2, PANC_NEIMF ;
DR   Q0ADS3, PANC_NITEC ;  Q82Y17, PANC_NITEU ;  Q1QKN4, PANC_NITHX ;
DR   Q2YAP0, PANC_NITMU ;  Q3JCP8, PANC_NITOC ;  A6Q581, PANC_NITSB ;
DR   Q3SRX8, PANC_NITWN ;  Q5Z2U3, PANC_NOCFA ;  A1SDW7, PANC_NOCSJ ;
DR   Q2G319, PANC_NOVAD ;  Q8CX59, PANC_OCEIH ;  A6WW03, PANC_OCHA4 ;
DR   O24210, PANC_ORYSJ ;  A6L8I6, PANC_PARD8 ;  A1B2L1, PANC_PARDP ;
DR   C6DC48, PANC_PECCP ;  Q3A3I7, PANC_PELCD ;  Q3B2E3, PANC_PELLD ;
DR   B4SDX5, PANC_PELPB ;  A1AUV7, PANC_PELPD ;  A5D5T5, PANC_PELTS ;
DR   Q4FLP6, PANC_PELUB ;  Q7N870, PANC_PHOLL ;  Q6LMJ5, PANC_PHOPR ;
DR   A1VKS2, PANC_POLNA ;  B1XVH8, PANC_POLNS ;  Q12F41, PANC_POLSJ ;
DR   A4SWJ8, PANC_POLSQ ;  B2RKW6, PANC_PORG3 ;  Q7MWV8, PANC_PORGI ;
DR   B4S5G6, PANC_PROA2 ;  B4EUD2, PANC_PROMH ;  A4SG25, PANC_PROVI ;
DR   Q48N87, PANC_PSE14 ;  Q15NV6, PANC_PSEA6 ;  A6VCI6, PANC_PSEA7 ;
DR   B7V1E2, PANC_PSEA8 ;  Q02FU2, PANC_PSEAB ;  Q9HV69, PANC_PSEAE ;
DR   Q1I4P1, PANC_PSEE4 ;  Q4K5Y3, PANC_PSEF5 ;  Q9ZEP7, PANC_PSEFS ;
DR   Q3ILL1, PANC_PSEHT ;  A4XYC5, PANC_PSEMY ;  A5W975, PANC_PSEP1 ;
DR   Q3K6Q5, PANC_PSEPF ;  B0KHW5, PANC_PSEPG ;  Q88DW8, PANC_PSEPK ;
DR   B1J2C1, PANC_PSEPW ;  Q888Q6, PANC_PSESM ;  Q4ZY87, PANC_PSEU2 ;
DR   A4VPM7, PANC_PSEU5 ;  Q4FVG7, PANC_PSYA2 ;  Q1QEJ3, PANC_PSYCK ;
DR   A1SSG8, PANC_PSYIN ;  A5WHC9, PANC_PSYWF ;  Q1LJM9, PANC_RALME ;
DR   B2UA33, PANC_RALPJ ;  Q8XWT3, PANC_RALSO ;  Q2JZU1, PANC_RHIEC ;
DR   Q1M4A1, PANC_RHIL3 ;  Q98ND0, PANC_RHILO ;  Q92NN0, PANC_RHIME ;
DR   C3MEL7, PANC_RHISN ;  Q7UTQ8, PANC_RHOBA ;  Q21U08, PANC_RHOFD ;
DR   Q2IXG7, PANC_RHOP2 ;  Q07L39, PANC_RHOP5 ;  Q6N528, PANC_RHOPA ;
DR   Q211R2, PANC_RHOPB ;  Q135F0, PANC_RHOPS ;  Q2RP31, PANC_RHORT ;
DR   A3PGQ3, PANC_RHOS1 ;  Q3J5N0, PANC_RHOS4 ;  B9KLD3, PANC_RHOSK ;
DR   Q0S8D5, PANC_RHOSR ;  A7NG78, PANC_ROSCS ;  Q16DW6, PANC_ROSDO ;
DR   A5URA7, PANC_ROSS1 ;  Q1AT82, PANC_RUBXD ;  A1AW71, PANC_RUTMC ;
DR   Q21LV6, PANC_SACD2 ;  A4F6T0, PANC_SACEN ;  B5F832, PANC_SALA4 ;
DR   A8M8F3, PANC_SALAI ;  A9MPM2, PANC_SALAR ;  Q57T74, PANC_SALCH ;
DR   B5FIX7, PANC_SALDC ;  B5R3E5, PANC_SALEP ;  B5RHC0, PANC_SALG2 ;
DR   B4TK04, PANC_SALHS ;  B4SUA7, PANC_SALNS ;  Q5PDB8, PANC_SALPA ;
DR   A9MZT0, PANC_SALPB ;  C0Q5P3, PANC_SALPC ;  B5BL64, PANC_SALPK ;
DR   Q2S2P6, PANC_SALRD ;  B4TXN3, PANC_SALSV ;  Q8Z9D3, PANC_SALTI ;
DR   A4XCQ4, PANC_SALTO ;  Q8ZRR1, PANC_SALTY ;  Q09673, PANC_SCHPO ;
DR   A8GIZ7, PANC_SERP5 ;  A1S3M6, PANC_SHEAM ;  B8EDX3, PANC_SHEB2 ;
DR   A3D8A9, PANC_SHEB5 ;  A6WJK9, PANC_SHEB8 ;  A9L2H4, PANC_SHEB9 ;
DR   Q12JC5, PANC_SHEDO ;  Q07XZ7, PANC_SHEFN ;  B0TTI1, PANC_SHEHH ;
DR   A3QHQ2, PANC_SHELP ;  Q8EIH0, PANC_SHEON ;  A8H0D3, PANC_SHEPA ;
DR   A4YA62, PANC_SHEPC ;  B8CTC7, PANC_SHEPW ;  A0L0R3, PANC_SHESA ;
DR   A8G085, PANC_SHESH ;  Q0HMB2, PANC_SHESM ;  Q0HRH5, PANC_SHESR ;
DR   A1RG66, PANC_SHESW ;  B1KEP7, PANC_SHEWM ;  B2U2Y0, PANC_SHIB3 ;
DR   Q326A4, PANC_SHIBS ;  Q32JW8, PANC_SHIDS ;  Q0T868, PANC_SHIF8 ;
DR   Q83SM0, PANC_SHIFL ;  Q3Z5M7, PANC_SHISS ;  Q5LWR2, PANC_SILPO ;
DR   Q1GLQ5, PANC_SILST ;  A6UB63, PANC_SINMW ;  Q2NVR3, PANC_SODGM ;
DR   A9ETA6, PANC_SORC5 ;  Q1GNR4, PANC_SPHAL ;  A5VA26, PANC_SPHWW ;
DR   A7X6X6, PANC_STAA1 ;  A6U4X8, PANC_STAA2 ;  Q2FDR1, PANC_STAA3 ;
DR   Q2FV22, PANC_STAA8 ;  A5IW23, PANC_STAA9 ;  Q2YWG0, PANC_STAAB ;
DR   Q5HCV4, PANC_STAAC ;  A6QK85, PANC_STAAE ;  P65658, PANC_STAAM ;
DR   P65659, PANC_STAAN ;  Q6GDK5, PANC_STAAR ;  Q6G678, PANC_STAAS ;
DR   A8Z3J8, PANC_STAAT ;  Q8NUN2, PANC_STAAW ;  B9DKF5, PANC_STACT ;
DR   Q5HL36, PANC_STAEQ ;  Q8CR21, PANC_STAES ;  Q4LA34, PANC_STAHJ ;
DR   Q4A0T9, PANC_STAS1 ;  Q82EC8, PANC_STRAW ;  Q9X844, PANC_STRCO ;
DR   B4SRY4, PANC_STRM5 ;  B2FL68, PANC_STRMK ;  Q30TN9, PANC_SULDN ;
DR   A6Q719, PANC_SULNB ;  B2V652, PANC_SULSY ;  Q2LSQ5, PANC_SYNAS ;
DR   A0LF67, PANC_SYNFM ;  Q0B0P5, PANC_SYNWW ;  C5BN51, PANC_TERTT ;
DR   B7IE21, PANC_THEAB ;  Q47KV5, PANC_THEFY ;  A8F7T6, PANC_THELT ;
DR   A6LNF3, PANC_THEM4 ;  Q9X0G6, PANC_THEMA ;  O86953, PANC_THENE ;
DR   A5IN99, PANC_THEP1 ;  B0KC91, PANC_THEP3 ;  B0K364, PANC_THEPX ;
DR   B1L843, PANC_THESQ ;  Q72HS0, PANC_THET2 ;  Q5SHF5, PANC_THET8 ;
DR   B5YJ91, PANC_THEYD ;  Q31FF6, PANC_THICR ;  Q3SH82, PANC_THIDA ;
DR   B8GNA8, PANC_THISH ;  C4L930, PANC_TOLAT ;  Q83ID9, PANC_TROW8 ;
DR   Q83H08, PANC_TROWT ;  B1GZJ9, PANC_UNCTG ;  C5CWV0, PANC_VARPS ;
DR   A1WDW5, PANC_VEREI ;  A5CX21, PANC_VESOH ;  A5F974, PANC_VIBC3 ;
DR   Q9KUD1, PANC_VIBCH ;  C3LS81, PANC_VIBCM ;  Q5E2T1, PANC_VIBF1 ;
DR   B5FB06, PANC_VIBFM ;  A7MYX3, PANC_VIBHB ;  Q87LV1, PANC_VIBPA ;
DR   B7VK04, PANC_VIBSL ;  Q8DC12, PANC_VIBVU ;  Q7MHV3, PANC_VIBVY ;
DR   Q8D2A6, PANC_WIGBR ;  Q7MAP3, PANC_WOLSU ;  Q8PLL0, PANC_XANAC ;
DR   Q3BUL5, PANC_XANC5 ;  Q4UTV6, PANC_XANC8 ;  B0RTU0, PANC_XANCB ;
DR   Q8P9S9, PANC_XANCP ;  Q2P378, PANC_XANOM ;  B2SJL9, PANC_XANOP ;
DR   Q5H0A4, PANC_XANOR ;  B2I721, PANC_XYLF2 ;  Q9PGR8, PANC_XYLFA ;
DR   B0U1Q3, PANC_XYLFM ;  Q87EV9, PANC_XYLFT ;  P40459, PANC_YEAST ;
DR   A1JJN7, PANC_YERE8 ;  A7FM23, PANC_YERP3 ;  Q1C3V7, PANC_YERPA ;
DR   B2K533, PANC_YERPB ;  Q8ZBK7, PANC_YERPE ;  A9R1G3, PANC_YERPG ;
DR   Q1CLW1, PANC_YERPN ;  A4TPV4, PANC_YERPP ;  Q66EG4, PANC_YERPS ;
DR   B1JK36, PANC_YERPY ;  Q5NL15, PANC_ZYMMO ;
//
ID   6.3.2.2
DE   Glutamate--cysteine ligase.
AN   Gamma-glutamyl-L-cysteine synthetase.
AN   Gamma-glutamylcysteine synthetase.
CA   ATP + L-glutamate + L-cysteine = ADP + phosphate + gamma-L-glutamyl-L-
CA   cysteine.
CC   -!- Can use L-aminohexanoate in place of glutamate.
DR   Q8GU95, GSH1A_ORYSI;  Q688Q9, GSH1A_ORYSJ;  A2YL07, GSH1B_ORYSI;
DR   Q6Z3A3, GSH1B_ORYSJ;  Q0VSY7, GSH1_ALCBS ;  B6EGB3, GSH1_ALISL ;
DR   P46309, GSH1_ARATH ;  C1DJH1, GSH1_AZOVD ;  Q1LTQ6, GSH1_BAUCH ;
DR   Q7WES2, GSH1_BORBR ;  Q7W3F2, GSH1_BORPA ;  A9HYE0, GSH1_BORPD ;
DR   O23736, GSH1_BRAJU ;  B8D9I8, GSH1_BUCA5 ;  P57485, GSH1_BUCAI ;
DR   P58994, GSH1_BUCAP ;  B8D7U0, GSH1_BUCAT ;  Q89AD8, GSH1_BUCBP ;
DR   Q20117, GSH1_CAEEL ;  Q9HF78, GSH1_CANAL ;  A8ANP6, GSH1_CITK8 ;
DR   Q97IV1, GSH1_CLOAB ;  Q54PC2, GSH1_DICDI ;  Q9W3K5, GSH1_DROME ;
DR   A7ZQC1, GSH1_ECO24 ;  B7UHB1, GSH1_ECO27 ;  B7MKG2, GSH1_ECO45 ;
DR   B7LEA4, GSH1_ECO55 ;  Q8X900, GSH1_ECO57 ;  B5Z2A3, GSH1_ECO5E ;
DR   B7NSH3, GSH1_ECO7I ;  B7MYJ3, GSH1_ECO81 ;  B7M9D0, GSH1_ECO8A ;
DR   C4ZYT8, GSH1_ECOBW ;  B1XCM1, GSH1_ECODH ;  A8A3H0, GSH1_ECOHS ;
DR   Q0TEI7, GSH1_ECOL5 ;  P0A6X0, GSH1_ECOL6 ;  B1IUY6, GSH1_ECOLC ;
DR   P0A6W9, GSH1_ECOLI ;  B7N6S3, GSH1_ECOLU ;  B6I679, GSH1_ECOSE ;
DR   B1LPG3, GSH1_ECOSM ;  Q1R808, GSH1_ECOUT ;  C5BGG7, GSH1_EDWI9 ;
DR   A4WDQ2, GSH1_ENT38 ;  A7MJ27, GSH1_ENTS8 ;  Q6D1T4, GSH1_ERWCT ;
DR   B2VHD0, GSH1_ERWT9 ;  B7LVZ1, GSH1_ESCF3 ;  Q2S8F7, GSH1_HAHCH ;
DR   P48506, GSH1_HUMAN ;  A6SX59, GSH1_JANMA ;  B5XVC3, GSH1_KLEP3 ;
DR   A6TCV4, GSH1_KLEP7 ;  Q72RD4, GSH1_LEPIC ;  Q8F4D5, GSH1_LEPIN ;
DR   Q9ZNX6, GSH1_MEDTR ;  P97494, GSH1_MOUSE ;  Q8X0X0, GSH1_NEUCR ;
DR   Q9NFN6, GSH1_ONCVO ;  C6DCQ5, GSH1_PECCP ;  Q7N7A4, GSH1_PHOLL ;
DR   Q6LMV1, GSH1_PHOPR ;  B4EUV9, GSH1_PROMH ;  Q48PX1, GSH1_PSE14 ;
DR   A6VDX9, GSH1_PSEA7 ;  B7V3V0, GSH1_PSEA8 ;  Q02EG1, GSH1_PSEAB ;
DR   Q9HTY6, GSH1_PSEAE ;  Q1IGL1, GSH1_PSEE4 ;  Q4KK14, GSH1_PSEF5 ;
DR   Q3IEB7, GSH1_PSEHT ;  A4XP63, GSH1_PSEMY ;  Q3KJQ5, GSH1_PSEPF ;
DR   Q88R90, GSH1_PSEPK ;  B1JET4, GSH1_PSEPW ;  Q88AR1, GSH1_PSESM ;
DR   P61379, GSH1_PSESY ;  Q4ZZU4, GSH1_PSEU2 ;  A4VG81, GSH1_PSEU5 ;
DR   P19468, GSH1_RAT   ;  Q21EP1, GSH1_SACD2 ;  B5F346, GSH1_SALA4 ;
DR   A9MFZ5, GSH1_SALAR ;  Q57KV3, GSH1_SALCH ;  B5FSX4, GSH1_SALDC ;
DR   B5QV72, GSH1_SALEP ;  B5RDE8, GSH1_SALG2 ;  B4TF06, GSH1_SALHS ;
DR   B4T394, GSH1_SALNS ;  Q5PF10, GSH1_SALPA ;  A9N0B5, GSH1_SALPB ;
DR   C0PWL7, GSH1_SALPC ;  B5BEN1, GSH1_SALPK ;  B4TT00, GSH1_SALSV ;
DR   Q8Z4D6, GSH1_SALTI ;  O68838, GSH1_SALTY ;  Q09768, GSH1_SCHPO ;
DR   A8GA13, GSH1_SERP5 ;  A1S4F9, GSH1_SHEAM ;  B0TK23, GSH1_SHEHH ;
DR   Q8EBF9, GSH1_SHEON ;  A8H1U8, GSH1_SHEPA ;  B2U053, GSH1_SHIB3 ;
DR   Q31X58, GSH1_SHIBS ;  Q32CN5, GSH1_SHIDS ;  Q0T1B9, GSH1_SHIF8 ;
DR   Q3YYH0, GSH1_SHISS ;  Q2NVK9, GSH1_SODGM ;  O22493, GSH1_SOLLC ;
DR   Q1W2L8, GSH1_TOBAC ;  Q9KUG5, GSH1_VIBCH ;  Q5E7F8, GSH1_VIBF1 ;
DR   B5FAD9, GSH1_VIBFM ;  A7MZY1, GSH1_VIBHB ;  Q87LS2, GSH1_VIBPA ;
DR   Q8DC38, GSH1_VIBVU ;  Q7MHS5, GSH1_VIBVY ;  Q8D2V5, GSH1_WIGBR ;
DR   P32477, GSH1_YEAST ;  A1JK14, GSH1_YERE8 ;  Q8ZBU2, GSH1_YERPE ;
DR   Q66E64, GSH1_YERPS ;  Q8XK30, GSHAB_CLOPE;  Q6ANW2, GSHAB_DESPS;
DR   Q82ZG8, GSHAB_ENTFA;  Q88UW5, GSHAB_LACPL;  Q926X7, GSHAB_LISIN;
DR   Q71VZ1, GSHAB_LISMF;  Q8Y3R3, GSHAB_LISMO;  A0AMA3, GSHAB_LISW6;
DR   Q65RX0, GSHAB_MANSM;  Q9CM00, GSHAB_PASMU;  Q8E399, GSHAB_STRA3;
DR   Q8DXM9, GSHAB_STRA5;  Q8DW15, GSHAB_STRMU;  Q5LYY5, GSHAB_STRT1;
DR   Q5M3J8, GSHAB_STRT2;
//
ID   6.3.2.3
DE   Glutathione synthase.
AN   Glutathione synthetase.
AN   GSH synthetase.
CA   ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate +
CA   glutathione.
PR   PROSITE; PDOC50975;
DR   Q8XK30, GSHAB_CLOPE;  Q6ANW2, GSHAB_DESPS;  Q82ZG8, GSHAB_ENTFA;
DR   Q88UW5, GSHAB_LACPL;  Q926X7, GSHAB_LISIN;  Q71VZ1, GSHAB_LISMF;
DR   Q8Y3R3, GSHAB_LISMO;  A0AMA3, GSHAB_LISW6;  Q65RX0, GSHAB_MANSM;
DR   Q9CM00, GSHAB_PASMU;  Q8E399, GSHAB_STRA3;  Q8DXM9, GSHAB_STRA5;
DR   Q8DW15, GSHAB_STRMU;  Q5LYY5, GSHAB_STRT1;  Q5M3J8, GSHAB_STRT2;
DR   Q8UII5, GSHB_AGRT5 ;  P35667, GSHB_ANACE ;  P46416, GSHB_ARATH ;
DR   Q7WKF5, GSHB_BORBR ;  Q7W910, GSHB_BORPA ;  Q7VY62, GSHB_BORPE ;
DR   Q5EAC2, GSHB_BOVIN ;  Q89WL0, GSHB_BRAJA ;  O23732, GSHB_BRAJU ;
DR   Q8YE82, GSHB_BRUME ;  Q8FXW6, GSHB_BRUSU ;  P57612, GSHB_BUCAI ;
DR   Q8K931, GSHB_BUCAP ;  P59495, GSHB_BUCBP ;  Q9ABS9, GSHB_CAUCR ;
DR   Q7NQ65, GSHB_CHRVO ;  Q83AL0, GSHB_COXBU ;  Q54E83, GSHB_DICDI ;
DR   P58578, GSHB_ECO57 ;  Q8FE30, GSHB_ECOL6 ;  P04425, GSHB_ECOLI ;
DR   Q7NF44, GSHB_GLOVI ;  P48637, GSHB_HUMAN ;  Q8HXX5, GSHB_MACFA ;
DR   P51855, GSHB_MOUSE ;  Q9JTJ6, GSHB_NEIMA ;  Q9JYJ3, GSHB_NEIMB ;
DR   Q82V16, GSHB_NITEU ;  P45480, GSHB_NOSS1 ;  Q7M7H8, GSHB_PHOLL ;
DR   Q7TVB0, GSHB_PROMA ;  Q7TUK9, GSHB_PROMM ;  Q7TUG9, GSHB_PROMP ;
DR   Q9I697, GSHB_PSEAE ;  Q88D35, GSHB_PSEPK ;  Q87VA4, GSHB_PSESM ;
DR   P58579, GSHB_RALSO ;  P46413, GSHB_RAT   ;  Q98DE8, GSHB_RHILO ;
DR   Q92SN3, GSHB_RHIME ;  P61396, GSHB_RHOPA ;  P58581, GSHB_SALTI ;
DR   P58580, GSHB_SALTY ;  P35669, GSHB_SCHPO ;  Q8EIK8, GSHB_SHEON ;
DR   Q83Q91, GSHB_SHIFL ;  O22494, GSHB_SOLLC ;  O32463, GSHB_SYNE7 ;
DR   Q7U3W8, GSHB_SYNPX ;  P73493, GSHB_SYNY3 ;  Q8DKF1, GSHB_THEEB ;
DR   Q9KUP7, GSHB_VIBCH ;  Q87LK1, GSHB_VIBPA ;  Q8DCA9, GSHB_VIBVU ;
DR   Q7MHK1, GSHB_VIBVY ;  Q8D335, GSHB_WIGBR ;  Q8PHZ5, GSHB_XANAC ;
DR   Q8P6P1, GSHB_XANCP ;  P35668, GSHB_XENLA ;  Q9PC29, GSHB_XYLFA ;
DR   Q87D42, GSHB_XYLFT ;  Q08220, GSHB_YEAST ;  P58582, GSHB_YERPE ;
//
ID   6.3.2.4
DE   D-alanine--D-alanine ligase.
AN   Alanine:alanine ligase (ADP-forming).
AN   Alanylalanine synthetase.
AN   D-Ala-D-Ala synthetase.
AN   D-alanyl-D-alanine synthetase.
AN   D-alanylalanine synthetase.
CA   ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.
CC   -!- Involved with EC 6.3.2.7 or EC 6.3.2.13, EC 6.3.2.8, EC 6.3.2.9 and
CC       EC 6.3.2.10 in the synthesis of a cell-wall peptide.
PR   PROSITE; PDOC00659;
PR   PROSITE; PDOC50975;
DR   Q81D33, DDLA_BACCR ;  Q89GA7, DDLA_BRAJA ;  Q8YHR9, DDLA_BRUME ;
DR   Q8G044, DDLA_BRUSU ;  Q7NV72, DDLA_CHRVO ;  Q8XKS9, DDLA_CLOPE ;
DR   Q897P8, DDLA_CLOTE ;  P0A6J9, DDLA_ECO57 ;  Q8FKE3, DDLA_ECOL6 ;
DR   P0A6J8, DDLA_ECOLI ;  Q9HWI0, DDLA_PSEAE ;  Q88EV6, DDLA_PSEPK ;
DR   Q87XJ6, DDLA_PSESM ;  Q98JS0, DDLA_RHILO ;  P0A1F1, DDLA_SALTI ;
DR   P0A1F0, DDLA_SALTY ;  P0A6K0, DDLA_SHIFL ;  Q8PDW3, DDLA_XANCP ;
DR   Q81IU1, DDLB_BACCR ;  Q89PS5, DDLB_BRAJA ;  Q8YI63, DDLB_BRUME ;
DR   Q8FZP5, DDLB_BRUSU ;  Q7NQ01, DDLB_CHRVO ;  Q8XM71, DDLB_CLOPE ;
DR   Q898Z5, DDLB_CLOTE ;  Q8X9Y6, DDLB_ECO57 ;  Q8FL63, DDLB_ECOL6 ;
DR   P07862, DDLB_ECOLI ;  Q9LCT6, DDLB_PSEAE ;  Q88N74, DDLB_PSEPK ;
DR   Q87WY7, DDLB_PSESM ;  Q98KB6, DDLB_RHILO ;  Q8Z9G7, DDLB_SALTI ;
DR   Q8ZRU1, DDLB_SALTY ;  Q83MF7, DDLB_SHIFL ;  Q8PCJ8, DDLB_XANCP ;
DR   B0CEL5, DDL_ACAM1  ;  A1TKD3, DDL_ACIAC  ;  Q6F705, DDL_ACIAD  ;
DR   B7GV75, DDL_ACIB3  ;  B7ICE3, DDL_ACIB5  ;  B2I1J3, DDL_ACIBC  ;
DR   B0VNZ7, DDL_ACIBS  ;  A3M9X9, DDL_ACIBT  ;  B0V9F7, DDL_ACIBY  ;
DR   A5FUL3, DDL_ACICJ  ;  B9MFR0, DDL_ACIET  ;  A1WC04, DDL_ACISJ  ;
DR   A3MY92, DDL_ACTP2  ;  B3GZL0, DDL_ACTP7  ;  B0BRH9, DDL_ACTPJ  ;
DR   A6VQN1, DDL_ACTSZ  ;  A0KKW8, DDL_AERHH  ;  A4SN40, DDL_AERS4  ;
DR   Q8UDN3, DDL_AGRT5  ;  Q0VS00, DDL_ALCBS  ;  Q0A6K5, DDL_ALHEH  ;
DR   P35660, DDL_ANACE  ;  B8J8F1, DDL_ANAD2  ;  Q2IG33, DDL_ANADE  ;
DR   A7HH70, DDL_ANADF  ;  B9KHS3, DDL_ANAMF  ;  Q5PBK2, DDL_ANAMM  ;
DR   B4UES4, DDL_ANASK  ;  B9MLC6, DDL_ANATD  ;  Q3MGA0, DDL_ANAVT  ;
DR   O66806, DDL_AQUAE  ;  Q5P6Z8, DDL_AROAE  ;  A1R7J5, DDL_ARTAT  ;
DR   B8HAC4, DDL_ARTCA  ;  A0JXX3, DDL_ARTS2  ;  A8HZA8, DDL_AZOC5  ;
DR   B6YQA7, DDL_AZOPC  ;  A1K3U8, DDL_AZOSB  ;  A7Z1L3, DDL_BACA2  ;
DR   C3PB71, DDL_BACAA  ;  C3LHM9, DDL_BACAC  ;  Q81Q29, DDL_BACAN  ;
DR   A7GKE0, DDL_BACCN  ;  Q5LI31, DDL_BACFN  ;  Q64Z37, DDL_BACFR  ;
DR   Q9KCF0, DDL_BACHD  ;  Q65N65, DDL_BACLD  ;  A8FA55, DDL_BACP2  ;
DR   Q5WDW9, DDL_BACSK  ;  P96612, DDL_BACSU  ;  Q8A1F3, DDL_BACTN  ;
DR   A6KXU3, DDL_BACV8  ;  A1UTC2, DDL_BARBK  ;  Q6G2Q8, DDL_BARHE  ;
DR   Q6FZ74, DDL_BARQU  ;  A9IWA2, DDL_BART1  ;  Q1LT82, DDL_BAUCH  ;
DR   Q6MQ94, DDL_BDEBA  ;  B2IGG3, DDL_BEII9  ;  B8DVN7, DDL_BIFA0  ;
DR   A0ZZT4, DDL_BIFAA  ;  B3DTT9, DDL_BIFLD  ;  Q8G7C4, DDL_BIFLO  ;
DR   B7GU04, DDL_BIFLS  ;  Q7VRX1, DDL_BLOFL  ;  Q492J5, DDL_BLOPB  ;
DR   Q2KVG4, DDL_BORA1  ;  Q0SNW3, DDL_BORAP  ;  Q7WFS4, DDL_BORBR  ;
DR   O51218, DDL_BORBU  ;  B7J1D2, DDL_BORBZ  ;  B5RL25, DDL_BORDL  ;
DR   Q662G4, DDL_BORGA  ;  B2RZR0, DDL_BORHD  ;  Q7W4B6, DDL_BORPA  ;
DR   A9I4V9, DDL_BORPD  ;  Q7VUQ5, DDL_BORPE  ;  B5RR18, DDL_BORRA  ;
DR   A1QYZ4, DDL_BORT9  ;  A5EMF5, DDL_BRASB  ;  A4YRU4, DDL_BRASO  ;
DR   O51927, DDL_BUCAP  ;  P59435, DDL_BUCBP  ;  B1YSS6, DDL_BURA4  ;
DR   Q1BZG1, DDL_BURCA  ;  B1JV80, DDL_BURCC  ;  A0K488, DDL_BURCH  ;
DR   B4E6J0, DDL_BURCJ  ;  Q0BIJ9, DDL_BURCM  ;  A9AI94, DDL_BURM1  ;
DR   A3MR65, DDL_BURM7  ;  A2S5U3, DDL_BURM9  ;  Q62GS9, DDL_BURMA  ;
DR   A1V0R6, DDL_BURMS  ;  A3NZL3, DDL_BURP0  ;  Q3JNE1, DDL_BURP1  ;
DR   A3NDW2, DDL_BURP6  ;  B2JHF8, DDL_BURP8  ;  B2SYX3, DDL_BURPP  ;
DR   Q63QJ9, DDL_BURPS  ;  Q2SZI1, DDL_BURTA  ;  A4JB96, DDL_BURVG  ;
DR   Q13TZ4, DDL_BURXL  ;  A4XJ89, DDL_CALS8  ;  A8Z6L3, DDL_CAMC1  ;
DR   A8FLL1, DDL_CAMJ8  ;  A7H451, DDL_CAMJD  ;  Q9PPC2, DDL_CAMJE  ;
DR   A1VZE6, DDL_CAMJJ  ;  Q5HUZ4, DDL_CAMJR  ;  B9KFX8, DDL_CAMLR  ;
DR   Q3ACF5, DDL_CARHZ  ;  Q9A5A9, DDL_CAUCR  ;  B0T824, DDL_CAUSK  ;
DR   Q3AS55, DDL_CHLCH  ;  B3EDF4, DDL_CHLL2  ;  B3QMS4, DDL_CHLP8  ;
DR   B3EQ14, DDL_CHLPB  ;  A1BH06, DDL_CHLPD  ;  B3QU24, DDL_CHLT3  ;
DR   Q8KCR8, DDL_CHLTE  ;  Q1QVG9, DDL_CHRSD  ;  Q97F58, DDL_CLOAB  ;
DR   A7FPH8, DDL_CLOB1  ;  C3L065, DDL_CLOB6  ;  A6LQY8, DDL_CLOB8  ;
DR   B2UY33, DDL_CLOBA  ;  B2TPY4, DDL_CLOBB  ;  A5HYZ6, DDL_CLOBH  ;
DR   C1FSC4, DDL_CLOBJ  ;  B1IEG9, DDL_CLOBK  ;  A7GAL4, DDL_CLOBL  ;
DR   B1KV16, DDL_CLOBM  ;  B8I590, DDL_CLOCE  ;  B9E560, DDL_CLOK1  ;
DR   A5N1C9, DDL_CLOK5  ;  A0Q323, DDL_CLONN  ;  Q0STC3, DDL_CLOPS  ;
DR   A3DGS7, DDL_CLOTH  ;  Q47VR1, DDL_COLP3  ;  B5Y8C8, DDL_COPPD  ;
DR   C3PFZ9, DDL_CORA7  ;  Q6NHK6, DDL_CORDI  ;  Q8FPQ9, DDL_COREF  ;
DR   A4QDT4, DDL_CORGB  ;  Q8NQV2, DDL_CORGL  ;  Q4JUX6, DDL_CORJK  ;
DR   B1VG49, DDL_CORU7  ;  B6J7Z1, DDL_COXB1  ;  A9KGD2, DDL_COXBN  ;
DR   A9N8L3, DDL_COXBR  ;  Q83BZ9, DDL_COXBU  ;  Q0K6M6, DDL_CUPNH  ;
DR   Q46WZ6, DDL_CUPPJ  ;  B3R6V7, DDL_CUPTR  ;  B7K991, DDL_CYAP7  ;
DR   B7JZB2, DDL_CYAP8  ;  Q47AA6, DDL_DECAR  ;  Q1IWG9, DDL_DEIGD  ;
DR   Q9RXF1, DDL_DEIRA  ;  A9BUK8, DDL_DELAS  ;  C6C0B2, DDL_DESAD  ;
DR   B1I3W6, DDL_DESAP  ;  B8IZ52, DDL_DESDA  ;  Q316H9, DDL_DESDG  ;
DR   C4XRH9, DDL_DESMR  ;  Q6ASD8, DDL_DESPS  ;  A4J5G8, DDL_DESRM  ;
DR   Q72F80, DDL_DESVH  ;  A1VGU5, DDL_DESVV  ;  A5EY21, DDL_DICNV  ;
DR   A8LS60, DDL_DINSH  ;  Q47758, DDL_ENTFA  ;  Q47823, DDL_ENTGA  ;
DR   Q47827, DDL_ENTHR  ;  Q6D0I5, DDL_ERWCT  ;  B2VD93, DDL_ERWT9  ;
DR   Q2NCY7, DDL_ERYLH  ;  A7HNE8, DDL_FERNB  ;  B0S093, DDL_FINM2  ;
DR   A5FGN3, DDL_FLAJ1  ;  A6GXD5, DDL_FLAPJ  ;  B0TVX5, DDL_FRAP2  ;
DR   Q2J6Y1, DDL_FRASC  ;  Q14JP9, DDL_FRAT1  ;  A7NET9, DDL_FRATF  ;
DR   Q2A182, DDL_FRATH  ;  A0Q4A6, DDL_FRATN  ;  Q0BK01, DDL_FRATO  ;
DR   Q5NI96, DDL_FRATT  ;  A4J053, DDL_FRATW  ;  Q8RDQ4, DDL_FUSNN  ;
DR   B5EBQ4, DDL_GEOBB  ;  Q5L3H2, DDL_GEOKA  ;  B3E3X9, DDL_GEOLS  ;
DR   Q748D8, DDL_GEOSL  ;  C6DZK9, DDL_GEOSM  ;  A4IJS8, DDL_GEOTN  ;
DR   A5G8J7, DDL_GEOUR  ;  Q7NNW1, DDL_GLOVI  ;  Q5FUJ2, DDL_GLUOX  ;
DR   Q0BV28, DDL_GRABC  ;  A0M4U5, DDL_GRAFK  ;  Q7VMY2, DDL_HAEDU  ;
DR   Q4QLF6, DDL_HAEI8  ;  A5UCW6, DDL_HAEIE  ;  A5UIR4, DDL_HAEIG  ;
DR   P44405, DDL_HAEIN  ;  B8F3B8, DDL_HAEPS  ;  Q0I1D1, DDL_HAES1  ;
DR   B0US69, DDL_HAES2  ;  A1WYU0, DDL_HALHL  ;  B8CWI5, DDL_HALOH  ;
DR   C4K734, DDL_HAMD5  ;  Q17XZ1, DDL_HELAH  ;  Q7VJW2, DDL_HELHP  ;
DR   B0TAZ6, DDL_HELMI  ;  B6JLX1, DDL_HELP2  ;  Q1CTD3, DDL_HELPH  ;
DR   Q9ZLA5, DDL_HELPJ  ;  B2UT94, DDL_HELPS  ;  P56191, DDL_HELPY  ;
DR   A9B406, DDL_HERA2  ;  A4G8T6, DDL_HERAR  ;  Q0C570, DDL_HYPNA  ;
DR   Q5R0N1, DDL_IDILO  ;  A6T2F6, DDL_JANMA  ;  Q28NP2, DDL_JANSC  ;
DR   A6W7R2, DDL_KINRD  ;  B2GFL1, DDL_KOCRD  ;  Q5FMN6, DDL_LACAC  ;
DR   Q03QZ9, DDL_LACBA  ;  Q03CR5, DDL_LACC3  ;  B3W7C1, DDL_LACCB  ;
DR   Q1G7Q5, DDL_LACDA  ;  Q04CI2, DDL_LACDB  ;  B2GAV5, DDL_LACF3  ;
DR   Q046V3, DDL_LACGA  ;  A8YWP6, DDL_LACH4  ;  Q74LS5, DDL_LACJO  ;
DR   Q9CIL5, DDL_LACLA  ;  A2RI72, DDL_LACLM  ;  Q031X8, DDL_LACLS  ;
DR   Q88UV8, DDL_LACPL  ;  A5VIS1, DDL_LACRD  ;  Q1WT60, DDL_LACS1  ;
DR   Q38ZM8, DDL_LACSS  ;  C1D5L4, DDL_LARHH  ;  Q1MQJ1, DDL_LAWIP  ;
DR   Q5X1S8, DDL_LEGPA  ;  A5IAW4, DDL_LEGPC  ;  Q5ZSA7, DDL_LEGPH  ;
DR   Q5WTI9, DDL_LEGPL  ;  B0S9U5, DDL_LEPBA  ;  Q04RK6, DDL_LEPBJ  ;
DR   Q052B5, DDL_LEPBL  ;  B0SS77, DDL_LEPBP  ;  Q72R93, DDL_LEPIC  ;
DR   Q8F4I2, DDL_LEPIN  ;  B1MWZ3, DDL_LEUCK  ;  Q48745, DDL_LEUME  ;
DR   Q03ZI1, DDL_LEUMM  ;  Q92DG5, DDL_LISIN  ;  Q721W2, DDL_LISMF  ;
DR   Q8Y8P1, DDL_LISMO  ;  A0AGY4, DDL_LISW6  ;  B9E8D0, DDL_MACCJ  ;
DR   Q2W0H0, DDL_MAGSA  ;  A0L5M8, DDL_MAGSM  ;  Q65RY9, DDL_MANSM  ;
DR   A1U3F6, DDL_MARAV  ;  Q0AMX1, DDL_MARMM  ;  A6VYJ6, DDL_MARMS  ;
DR   Q11GS8, DDL_MESSB  ;  B7KSC6, DDL_METC4  ;  Q604W0, DDL_METCA  ;
DR   A9VWV8, DDL_METEP  ;  Q1GZ04, DDL_METFK  ;  B3DVV9, DDL_METI4  ;
DR   B1ZGP9, DDL_METPB  ;  A2SCY7, DDL_METPP  ;  B1LXZ1, DDL_METRJ  ;
DR   B0UB90, DDL_METS4  ;  B8ETM9, DDL_METSB  ;  B0JHC1, DDL_MICAN  ;
DR   Q2RJD5, DDL_MOOTA  ;  A0QJB2, DDL_MYCA1  ;  Q7TXH9, DDL_MYCBO  ;
DR   A1KMX5, DDL_MYCBP  ;  A4TE25, DDL_MYCGI  ;  Q9CBS0, DDL_MYCLE  ;
DR   Q73VJ4, DDL_MYCPA  ;  A0QUZ7, DDL_MYCS2  ;  A3PXS0, DDL_MYCSJ  ;
DR   A1UEB6, DDL_MYCSK  ;  Q9ZGN0, DDL_MYCSM  ;  Q1BAP6, DDL_MYCSS  ;
DR   A5U6Z2, DDL_MYCTA  ;  P95114, DDL_MYCTU  ;  A0PQ03, DDL_MYCUA  ;
DR   A1T708, DDL_MYCVP  ;  B2A2Z6, DDL_NATTJ  ;  Q5F6M0, DDL_NEIG1  ;
DR   B4RQC3, DDL_NEIG2  ;  Q9JSZ9, DDL_NEIMA  ;  Q9K0Y0, DDL_NEIMB  ;
DR   A1KVL1, DDL_NEIMF  ;  Q0AJE4, DDL_NITEC  ;  Q82VS0, DDL_NITEU  ;
DR   Q2Y641, DDL_NITMU  ;  Q3J792, DDL_NITOC  ;  A6Q3Z7, DDL_NITSB  ;
DR   Q5YRY7, DDL_NOCFA  ;  B2J0J6, DDL_NOSP7  ;  Q8YY71, DDL_NOSS1  ;
DR   Q2G992, DDL_NOVAD  ;  Q8ERJ6, DDL_OCEIH  ;  A6WZQ9, DDL_OCHA4  ;
DR   Q04G13, DDL_OENOB  ;  B6JB38, DDL_OLICO  ;  A6LFD0, DDL_PARD8  ;
DR   A7HVV0, DDL_PARL1  ;  P57819, DDL_PASMU  ;  C6DEU1, DDL_PECCP  ;
DR   Q03EM9, DDL_PEDPA  ;  Q3A2G9, DDL_PELCD  ;  Q3B391, DDL_PELLD  ;
DR   B4SAI2, DDL_PELPB  ;  A1AU58, DDL_PELPD  ;  A5D2F9, DDL_PELTS  ;
DR   Q4FPK8, DDL_PELUB  ;  A9BI46, DDL_PETMO  ;  Q7N149, DDL_PHOLL  ;
DR   A1VST4, DDL_POLNA  ;  B1XT11, DDL_POLNS  ;  Q12EL3, DDL_POLSJ  ;
DR   A4SV76, DDL_POLSQ  ;  B2RIT4, DDL_PORG3  ;  Q7MWA2, DDL_PORGI  ;
DR   B4S8W3, DDL_PROA2  ;  A3PEE0, DDL_PROM0  ;  A2C472, DDL_PROM1  ;
DR   A8G6B7, DDL_PROM2  ;  A2CB75, DDL_PROM3  ;  A2BY13, DDL_PROM5  ;
DR   Q319I3, DDL_PROM9  ;  Q7VAS4, DDL_PROMA  ;  B4ETX3, DDL_PROMH  ;
DR   Q7V8L9, DDL_PROMM  ;  Q7V0F6, DDL_PROMP  ;  A2BSM7, DDL_PROMS  ;
DR   Q46JG5, DDL_PROMT  ;  A4SE28, DDL_PROVI  ;  Q15Q19, DDL_PSEA6  ;
DR   Q1I5C0, DDL_PSEE4  ;  Q3IFY2, DDL_PSEHT  ;  A4XQS6, DDL_PSEMY  ;
DR   Q3K746, DDL_PSEPF  ;  B0KFS4, DDL_PSEPG  ;  A4VII0, DDL_PSEU5  ;
DR   A5WCU0, DDL_PSYWF  ;  Q1LIM8, DDL_RALME  ;  B2UCX5, DDL_RALPJ  ;
DR   Q8XVI9, DDL_RALSO  ;  Q92NM4, DDL_RHIME  ;  C3MEM6, DDL_RHISN  ;
DR   C0ZXN9, DDL_RHOE4  ;  Q21SX1, DDL_RHOFD  ;  C1B2N8, DDL_RHOOB  ;
DR   Q07PS7, DDL_RHOP5  ;  Q211U3, DDL_RHOPB  ;  Q2RVU7, DDL_RHORT  ;
DR   A3PHT2, DDL_RHOS1  ;  Q3J4L8, DDL_RHOS4  ;  A4WQD9, DDL_RHOS5  ;
DR   Q0S2F6, DDL_RHOSR  ;  C3PMU6, DDL_RICAE  ;  A8GMP8, DDL_RICAH  ;
DR   A8GW96, DDL_RICB8  ;  Q1RHX2, DDL_RICBR  ;  A8EXZ8, DDL_RICCK  ;
DR   Q92IT7, DDL_RICCN  ;  Q4UKP1, DDL_RICFE  ;  A8F110, DDL_RICM5  ;
DR   Q9ZDS6, DDL_RICPR  ;  C4K126, DDL_RICPU  ;  B0BWS2, DDL_RICRO  ;
DR   A8GRC1, DDL_RICRS  ;  Q68XC0, DDL_RICTY  ;  Q163J4, DDL_ROSDO  ;
DR   A1AX29, DDL_RUTMC  ;  Q21MG7, DDL_SACD2  ;  Q5PDC6, DDL_SALPA  ;
DR   B5BLC4, DDL_SALPK  ;  A1S6V2, DDL_SHEAM  ;  B8E569, DDL_SHEB2  ;
DR   A6WMZ6, DDL_SHEB8  ;  A9L0H9, DDL_SHEB9  ;  Q12LP2, DDL_SHEDO  ;
DR   Q080C3, DDL_SHEFN  ;  B0TRK1, DDL_SHEHH  ;  A3QEV1, DDL_SHELP  ;
DR   Q8EEZ2, DDL_SHEON  ;  A8H5A5, DDL_SHEPA  ;  A4Y6E2, DDL_SHEPC  ;
DR   B8CMV8, DDL_SHEPW  ;  A0KXL7, DDL_SHESA  ;  A8FUK8, DDL_SHESH  ;
DR   Q0HIB5, DDL_SHESM  ;  Q0HUL2, DDL_SHESR  ;  A1RK54, DDL_SHESW  ;
DR   B1KI99, DDL_SHEWM  ;  Q5LU57, DDL_SILPO  ;  Q1GIU7, DDL_SILST  ;
DR   A6UB80, DDL_SINMW  ;  Q2NUK1, DDL_SODGM  ;  Q023Q5, DDL_SOLUE  ;
DR   Q1GRY2, DDL_SPHAL  ;  A5VDC2, DDL_SPHWW  ;  A7X4R6, DDL_STAA1  ;
DR   A6U3G9, DDL_STAA2  ;  Q2FF43, DDL_STAA3  ;  Q2FWH3, DDL_STAA8  ;
DR   A5IUM9, DDL_STAA9  ;  Q2YUH1, DDL_STAAB  ;  Q5HEB7, DDL_STAAC  ;
DR   A6QIS7, DDL_STAAE  ;  P63891, DDL_STAAM  ;  P63892, DDL_STAAN  ;
DR   Q6GEZ1, DDL_STAAR  ;  Q6G7M7, DDL_STAAS  ;  A8Z4Y6, DDL_STAAT  ;
DR   Q8NVH8, DDL_STAAW  ;  B9DMH1, DDL_STACT  ;  Q5HMD8, DDL_STAEQ  ;
DR   Q8CRP5, DDL_STAES  ;  Q4L7W2, DDL_STAHJ  ;  Q49Z31, DDL_STAS1  ;
DR   Q3K1T9, DDL_STRA1  ;  Q8E640, DDL_STRA3  ;  Q8E0G6, DDL_STRA5  ;
DR   Q82JS5, DDL_STRAW  ;  Q9ZBR9, DDL_STRCO  ;  C0M8S4, DDL_STRE4  ;
DR   B4U1Z2, DDL_STREM  ;  A8AY66, DDL_STRGC  ;  B1VYZ5, DDL_STRGG  ;
DR   P95803, DDL_STRMU  ;  Q99Z34, DDL_STRP1  ;  Q04J98, DDL_STRP2  ;
DR   P0DA50, DDL_STRP3  ;  B5E721, DDL_STRP4  ;  Q5XB93, DDL_STRP6  ;
DR   Q8P0C4, DDL_STRP8  ;  Q1JAX7, DDL_STRPB  ;  Q1JL27, DDL_STRPC  ;
DR   Q1JG50, DDL_STRPD  ;  Q1J5W7, DDL_STRPF  ;  A2RDW0, DDL_STRPG  ;
DR   B1I733, DDL_STRPI  ;  B8ZM66, DDL_STRPJ  ;  Q48SP8, DDL_STRPM  ;
DR   P0CB57, DDL_STRPN  ;  P0DA51, DDL_STRPQ  ;  B2IRS6, DDL_STRPS  ;
DR   B5XM63, DDL_STRPZ  ;  Q8DNV5, DDL_STRR6  ;  C0MCV8, DDL_STRS7  ;
DR   A3CLS3, DDL_STRSV  ;  Q5LYJ2, DDL_STRT1  ;  Q5M355, DDL_STRT2  ;
DR   Q03JC6, DDL_STRTD  ;  B9DUS0, DDL_STRU0  ;  C1CFP2, DDL_STRZJ  ;
DR   C1CM10, DDL_STRZP  ;  C1CST6, DDL_STRZT  ;  Q30R95, DDL_SULDN  ;
DR   A6Q6M8, DDL_SULNB  ;  Q31KL4, DDL_SYNE7  ;  A0LQR5, DDL_SYNFM  ;
DR   Q2JXY2, DDL_SYNJA  ;  Q2JJV2, DDL_SYNJB  ;  B1XNQ0, DDL_SYNP2  ;
DR   Q5N1A0, DDL_SYNP6  ;  A5GML7, DDL_SYNPW  ;  Q7U5Q9, DDL_SYNPX  ;
DR   A5GRJ7, DDL_SYNR3  ;  Q0IC71, DDL_SYNS3  ;  Q3AV89, DDL_SYNS9  ;
DR   Q3ALB5, DDL_SYNSC  ;  Q0AXT9, DDL_SYNWW  ;  P73632, DDL_SYNY3  ;
DR   B7IGP0, DDL_THEAB  ;  Q8DLH0, DDL_THEEB  ;  A8F8C8, DDL_THELT  ;
DR   A6LKA2, DDL_THEM4  ;  P46805, DDL_THEMA  ;  A5IKG2, DDL_THEP1  ;
DR   B0KBI1, DDL_THEP3  ;  B0K485, DDL_THEPX  ;  B1L9P4, DDL_THESQ  ;
DR   Q72IA9, DDL_THET2  ;  Q5SHZ3, DDL_THET8  ;  Q8R778, DDL_THETN  ;
DR   B5YFT1, DDL_THEYD  ;  Q31I42, DDL_THICR  ;  Q3SMH0, DDL_THIDA  ;
DR   C4L8J2, DDL_TOLAT  ;  Q73JN2, DDL_TREDE  ;  O83676, DDL_TREPA  ;
DR   B2S3Q9, DDL_TREPS  ;  Q10X06, DDL_TRIEI  ;  Q83I36, DDL_TROW8  ;
DR   Q83G28, DDL_TROWT  ;  A1WRL3, DDL_VEREI  ;  A5CW55, DDL_VESOH  ;
DR   A5F083, DDL_VIBC3  ;  Q9KM17, DDL_VIBCH  ;  C3LVI8, DDL_VIBCM  ;
DR   Q5E006, DDL_VIBF1  ;  B5ETW5, DDL_VIBFM  ;  A7N512, DDL_VIBHB  ;
DR   Q87HS0, DDL_VIBPA  ;  B7VRZ7, DDL_VIBSL  ;  Q8D781, DDL_VIBVU  ;
DR   Q7ME85, DDL_VIBVY  ;  Q8D2Y5, DDL_WIGBR  ;  Q73IQ8, DDL_WOLPM  ;
DR   B3CPK8, DDL_WOLPP  ;  Q7MA71, DDL_WOLSU  ;  Q5GS66, DDL_WOLTR  ;
DR   C0R5F9, DDL_WOLWR  ;  Q8PPA6, DDL_XANAC  ;  A7IC40, DDL_XANP2  ;
DR   Q9PF79, DDL_XYLFA  ;  Q87AG1, DDL_XYLFT  ;  A7FM64, DDL_YERP3  ;
DR   Q1C216, DDL_YERPA  ;  B2K4E8, DDL_YERPB  ;  Q8ZIE7, DDL_YERPE  ;
DR   A9R122, DDL_YERPG  ;  Q1CMM5, DDL_YERPN  ;  A4TQ81, DDL_YERPP  ;
DR   Q66EK3, DDL_YERPS  ;  B1JK79, DDL_YERPY  ;  Q9RNM9, DDL_ZYMMO  ;
DR   Q821S4, MUDD_CHLCV ;  Q9PLG1, MUDD_CHLMU ;  Q9Z701, MUDD_CHLPN ;
DR   O84767, MUDD_CHLTR ;
//
ID   6.3.2.5
DE   Phosphopantothenate--cysteine ligase.
AN   Phosphopantothenoylcysteine synthetase.
CA   CTP + (R)-4'-phosphopantothenate + L-cysteine = CMP + PPi + N-((R)-
CA   4'-phosphopantothenoyl)-L-cysteine.
CC   -!- Cysteine can be replaced by some of its derivatives.
DR   O35033, COABC_BACSU;  O51752, COABC_BORBU;  P0ABQ1, COABC_ECOL6;
DR   P0ABQ0, COABC_ECOLI;  P44953, COABC_HAEIN;  Q58323, COABC_METJA;
DR   P67734, COABC_MYCBO;  P67733, COABC_MYCTU;  P73881, COABC_SYNY3;
DR   Q9KVD1, COABC_VIBCH;  Q5E8M6, COABC_VIBF1;  Q87T89, COABC_VIBPA;
DR   Q8DDX8, COABC_VIBVU;  Q7MPS9, COABC_VIBVY;  Q8GXR5, PPCS1_ARATH;
DR   Q9LZM3, PPCS2_ARATH;  Q9HAB8, PPCS_HUMAN ;  Q8VDG5, PPCS_MOUSE ;
DR   P40506, PPCS_YEAST ;
//
ID   6.3.2.6
DE   Phosphoribosylaminoimidazolesuccinocarboxamide synthase.
AN   4-((N-succinylamino)carbonyl)-5-aminoimidazole ribonucleotide synthetase.
AN   4-(N-succinocarboxamide)-5-aminoimidazole synthetase.
AN   5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase.
AN   Phosphoribosylaminoimidazole-succinocarboxamide synthase.
AN   Phosphoribosylaminoimidazole-succinocarboxamide synthetase.
AN   Phosphoribosylaminoimidazolesuccinocarboxamide synthetase.
AN   SAICAR synthase.
AN   SAICAR synthetase.
AN   SAICARs.
CA   ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate +
CA   L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-
CA   ribosyl)imidazole-4-carboxamido)succinate.
CC   -!- Forms part of the purine biosynthesis pathway.
PR   PROSITE; PDOC00810;
DR   Q10457, PUR6_CAEEL ;  P38024, PUR6_CHICK ;  Q9I7S8, PUR6_DROME ;
DR   P22234, PUR6_HUMAN ;  Q9DCL9, PUR6_MOUSE ;  Q5RB59, PUR6_PONAB ;
DR   P51583, PUR6_RAT   ;  Q8UEB7, PUR71_AGRT5;  Q89IB0, PUR71_BRAJA;
DR   Q9A5F9, PUR71_CAUCR;  Q98NM8, PUR71_RHILO;  Q8UCE7, PUR72_AGRT5;
DR   Q89W81, PUR72_BRAJA;  Q9A3G2, PUR72_CAUCR;  Q98I23, PUR72_RHILO;
DR   B0CD47, PUR7_ACAM1 ;  Q6F6U0, PUR7_ACIAD ;  B7GV30, PUR7_ACIB3 ;
DR   B7I289, PUR7_ACIB5 ;  B2I2E3, PUR7_ACIBC ;  B0VPX5, PUR7_ACIBS ;
DR   A3MA70, PUR7_ACIBT ;  B0VA00, PUR7_ACIBY ;  A5FVI6, PUR7_ACICJ ;
DR   B7J6C1, PUR7_ACIF2 ;  B5ELM2, PUR7_ACIF5 ;  A6VN04, PUR7_ACTSZ ;
DR   A4SR47, PUR7_AERS4 ;  B2UP00, PUR7_AKKM8 ;  Q0VRH1, PUR7_ALCBS ;
DR   B6EMJ7, PUR7_ALISL ;  B4RZW3, PUR7_ALTMD ;  Q3MH17, PUR7_ANAVT ;
DR   B7GFT5, PUR7_ANOFW ;  O67881, PUR7_AQUAE ;  P38025, PUR7_ARATH ;
DR   O28996, PUR7_ARCFU ;  Q5P7J7, PUR7_AROAE ;  B6YRK7, PUR7_AZOPC ;
DR   A1K9I4, PUR7_AZOSB ;  C3PBM7, PUR7_BACAA ;  C3L529, PUR7_BACAC ;
DR   Q81ZH5, PUR7_BACAN ;  B7JM82, PUR7_BACC0 ;  Q73EN8, PUR7_BACC1 ;
DR   B7IUV0, PUR7_BACC2 ;  C1EV60, PUR7_BACC3 ;  B7H4T3, PUR7_BACC4 ;
DR   B7HS29, PUR7_BACC7 ;  A7GKH5, PUR7_BACCN ;  B9J1K2, PUR7_BACCQ ;
DR   Q81IQ6, PUR7_BACCR ;  Q63GT6, PUR7_BACCZ ;  Q5LH03, PUR7_BACFN ;
DR   Q64XV7, PUR7_BACFR ;  Q9KF60, PUR7_BACHD ;  Q6HPA7, PUR7_BACHK ;
DR   Q5WJ89, PUR7_BACSK ;  P12046, PUR7_BACSU ;  Q8A004, PUR7_BACTN ;
DR   A9VRE8, PUR7_BACWK ;  Q6G338, PUR7_BARHE ;  Q6FZJ2, PUR7_BARQU ;
DR   A9IVH1, PUR7_BART1 ;  Q1LU15, PUR7_BAUCH ;  B8DTV0, PUR7_BIFA0 ;
DR   A1A0S2, PUR7_BIFAA ;  B3DT37, PUR7_BIFLD ;  Q8G5A9, PUR7_BIFLO ;
DR   B7GU64, PUR7_BIFLS ;  Q7WMI1, PUR7_BORBR ;  Q7WB15, PUR7_BORPA ;
DR   A9HZF7, PUR7_BORPD ;  Q7VY42, PUR7_BORPE ;  C0ZKC3, PUR7_BREBN ;
DR   B2S578, PUR7_BRUA1 ;  Q2YNG1, PUR7_BRUA2 ;  Q57DR3, PUR7_BRUAB ;
DR   A9MAL9, PUR7_BRUC2 ;  C0RIH6, PUR7_BRUMB ;  Q8YGN6, PUR7_BRUME ;
DR   A5VQ20, PUR7_BRUO2 ;  B0CLG9, PUR7_BRUSI ;  Q8G178, PUR7_BRUSU ;
DR   A8MCJ8, PUR7_CALMQ ;  A7ZD85, PUR7_CAMC1 ;  A7GYK7, PUR7_CAMC5 ;
DR   A0RPI2, PUR7_CAMFF ;  A7I1M0, PUR7_CAMHC ;  A8FKT8, PUR7_CAMJ8 ;
DR   A7H4M4, PUR7_CAMJD ;  Q9PHZ9, PUR7_CAMJE ;  A1VYM4, PUR7_CAMJJ ;
DR   Q5HVQ1, PUR7_CAMJR ;  P43060, PUR7_CANAL ;  P27602, PUR7_CANMA ;
DR   B3PC16, PUR7_CELJU ;  A0RW02, PUR7_CENSY ;  A9WK38, PUR7_CHLAA ;
DR   B8GCM2, PUR7_CHLAD ;  Q3AQN3, PUR7_CHLCH ;  B3ECH5, PUR7_CHLL2 ;
DR   B3QP02, PUR7_CHLP8 ;  B3EQL0, PUR7_CHLPB ;  A1BF89, PUR7_CHLPD ;
DR   B9LC05, PUR7_CHLSY ;  B3QYX5, PUR7_CHLT3 ;  Q8KDT4, PUR7_CHLTE ;
DR   Q1QTP9, PUR7_CHRSD ;  Q7P1P8, PUR7_CHRVO ;  A8ADB1, PUR7_CITK8 ;
DR   Q97J95, PUR7_CLOAB ;  A7FXD7, PUR7_CLOB1 ;  C3L2V3, PUR7_CLOB6 ;
DR   A6LSA9, PUR7_CLOB8 ;  B2V3B9, PUR7_CLOBA ;  B2TN72, PUR7_CLOBB ;
DR   A5I5W3, PUR7_CLOBH ;  C1FV80, PUR7_CLOBJ ;  B1IL61, PUR7_CLOBK ;
DR   A7GHA0, PUR7_CLOBL ;  B1KZ59, PUR7_CLOBM ;  B9E4L0, PUR7_CLOK1 ;
DR   A5N0Q4, PUR7_CLOK5 ;  A0Q1J4, PUR7_CLONN ;  Q0TTB4, PUR7_CLOP1 ;
DR   Q8XMK6, PUR7_CLOPE ;  A9KQ90, PUR7_CLOPH ;  Q0SV52, PUR7_CLOPS ;
DR   Q895U7, PUR7_CLOTE ;  Q480B3, PUR7_COLP3 ;  B5Y714, PUR7_COPPD ;
DR   Q9RHX2, PUR7_CORAM ;  Q6NFG4, PUR7_CORDI ;  Q8FML6, PUR7_COREF ;
DR   A4QGZ4, PUR7_CORGB ;  Q8NMH6, PUR7_CORGL ;  B1VIK2, PUR7_CORU7 ;
DR   Q83CA8, PUR7_COXBU ;  Q0KE53, PUR7_CUPNH ;  Q475J5, PUR7_CUPPJ ;
DR   B2AHE3, PUR7_CUPTR ;  B8HK56, PUR7_CYAP4 ;  P50124, PUR7_CYBJA ;
DR   Q11TT6, PUR7_CYTH3 ;  Q479W2, PUR7_DECAR ;  C1CYX1, PUR7_DEIDV ;
DR   Q1J2B4, PUR7_DEIGD ;  Q9RXT0, PUR7_DEIRA ;  B8FI50, PUR7_DESAA ;
DR   C6BVA6, PUR7_DESAD ;  C0QH22, PUR7_DESAH ;  B8FP01, PUR7_DESHD ;
DR   Q24QH2, PUR7_DESHY ;  A8ZVI6, PUR7_DESOH ;  Q6AK95, PUR7_DESPS ;
DR   A4J726, PUR7_DESRM ;  A5EXP1, PUR7_DICNV ;  A8LSK4, PUR7_DINSH ;
DR   A7ZPS1, PUR7_ECO24 ;  B7UGM6, PUR7_ECO27 ;  B7MHW9, PUR7_ECO45 ;
DR   B7LCL4, PUR7_ECO55 ;  P0A7D9, PUR7_ECO57 ;  B5Z013, PUR7_ECO5E ;
DR   B7NQL4, PUR7_ECO7I ;  B7MYB5, PUR7_ECO81 ;  B7M7H9, PUR7_ECO8A ;
DR   C4ZX51, PUR7_ECOBW ;  B1XAE8, PUR7_ECODH ;  A8A2W8, PUR7_ECOHS ;
DR   Q0TF00, PUR7_ECOL5 ;  P0A7D8, PUR7_ECOL6 ;  B1IWI3, PUR7_ECOLC ;
DR   P0A7D7, PUR7_ECOLI ;  B7N658, PUR7_ECOLU ;  B6I546, PUR7_ECOSE ;
DR   B1LNC6, PUR7_ECOSM ;  C5B7A4, PUR7_EDWI9 ;  Q2GHH2, PUR7_EHRCR ;
DR   B2KCE9, PUR7_ELUMP ;  A4WD56, PUR7_ENT38 ;  Q833Y6, PUR7_ENTFA ;
DR   A7ML04, PUR7_ENTS8 ;  Q6D7R1, PUR7_ERWCT ;  B2VE61, PUR7_ERWT9 ;
DR   Q2NCK7, PUR7_ERYLH ;  B7LKG5, PUR7_ESCF3 ;  C4Z3J8, PUR7_EUBE2 ;
DR   B1YJ02, PUR7_EXIS2 ;  C4L296, PUR7_EXISA ;  B0S341, PUR7_FINM2 ;
DR   A6GYJ4, PUR7_FLAPJ ;  Q8REV1, PUR7_FUSNN ;  B5EGN6, PUR7_GEOBB ;
DR   B3E940, PUR7_GEOLS ;  Q39X66, PUR7_GEOMG ;  B9M5S1, PUR7_GEOSF ;
DR   Q74BF0, PUR7_GEOSL ;  C6E6C1, PUR7_GEOSM ;  A5G5H3, PUR7_GEOUR ;
DR   Q7NJB6, PUR7_GLOVI ;  A9HJF3, PUR7_GLUDA ;  Q5FNL4, PUR7_GLUOX ;
DR   A5UBF4, PUR7_HAEIE ;  A5UFF7, PUR7_HAEIG ;  P43851, PUR7_HAEIN ;
DR   B0UW56, PUR7_HAES2 ;  Q2SCM9, PUR7_HAHCH ;  A1WVI0, PUR7_HALHL ;
DR   Q9HNU7, PUR7_HALSA ;  C4K789, PUR7_HAMD5 ;  Q7VFQ6, PUR7_HELHP ;
DR   A9B302, PUR7_HERA2 ;  Q0BYZ9, PUR7_HYPNA ;  Q5QU05, PUR7_IDILO ;
DR   Q28PA0, PUR7_JANSC ;  B5XVM9, PUR7_KLEP3 ;  A6TC99, PUR7_KLEP7 ;
DR   Q037U6, PUR7_LACC3 ;  B3WFA0, PUR7_LACCB ;  B2GF71, PUR7_LACF3 ;
DR   O68830, PUR7_LACLA ;  Q9R7D5, PUR7_LACLC ;  Q02Y52, PUR7_LACLS ;
DR   Q88U22, PUR7_LACPL ;  Q38XX0, PUR7_LACSS ;  Q5X4M9, PUR7_LEGPA ;
DR   Q5WW20, PUR7_LEGPL ;  Q6ACE5, PUR7_LEIXX ;  B1XWZ1, PUR7_LEPCP ;
DR   Q72UH8, PUR7_LEPIC ;  Q8F0I0, PUR7_LEPIN ;  Q92AN6, PUR7_LISIN ;
DR   C1KW71, PUR7_LISMC ;  Q71YP6, PUR7_LISMF ;  B8DDY5, PUR7_LISMH ;
DR   Q8Y6B9, PUR7_LISMO ;  A0AJM6, PUR7_LISW6 ;  B1HTV1, PUR7_LYSSC ;
DR   B9EAY5, PUR7_MACCJ ;  A0L4X9, PUR7_MAGSM ;  Q65SH2, PUR7_MANSM ;
DR   A1U1A4, PUR7_MARAV ;  Q0AQW2, PUR7_MARMM ;  A6VX88, PUR7_MARMS ;
DR   Q11IU8, PUR7_MESSB ;  Q8TIS9, PUR7_METAC ;  A7IAF5, PUR7_METB6 ;
DR   Q46F30, PUR7_METBF ;  Q12UF8, PUR7_METBU ;  Q60CQ5, PUR7_METCA ;
DR   Q1GZ28, PUR7_METFK ;  Q58987, PUR7_METJA ;  Q8TX83, PUR7_METKA ;
DR   Q8PYK6, PUR7_METMA ;  A3CWL5, PUR7_METMJ ;  A2SCG5, PUR7_METPP ;
DR   A5UNH4, PUR7_METS3 ;  O26272, PUR7_METTH ;  B1MHW4, PUR7_MYCA9 ;
DR   P0A5T5, PUR7_MYCBO ;  A1KGR3, PUR7_MYCBP ;  C1ALB6, PUR7_MYCBT ;
DR   A4T7K2, PUR7_MYCGI ;  B8ZSW0, PUR7_MYCLB ;  O08361, PUR7_MYCLE ;
DR   B2HH58, PUR7_MYCMM ;  A0R4I0, PUR7_MYCS2 ;  A3Q6D1, PUR7_MYCSJ ;
DR   A1ULY1, PUR7_MYCSK ;  Q1B370, PUR7_MYCSS ;  A5U0G8, PUR7_MYCTA ;
DR   P0A5T4, PUR7_MYCTU ;  A0PLI0, PUR7_MYCUA ;  A1TFF9, PUR7_MYCVP ;
DR   B9L8V5, PUR7_NAUPA ;  A9M3I9, PUR7_NEIM0 ;  Q9JV73, PUR7_NEIMA ;
DR   Q9K063, PUR7_NEIMB ;  Q2GCS7, PUR7_NEOSM ;  Q82W32, PUR7_NITEU ;
DR   A9A5G9, PUR7_NITMS ;  Q3J871, PUR7_NITOC ;  A6Q3C7, PUR7_NITSB ;
DR   B2IWK4, PUR7_NOSP7 ;  Q8YUR7, PUR7_NOSS1 ;  Q2G9I7, PUR7_NOVAD ;
DR   Q8ES99, PUR7_OCEIH ;  A6X1J2, PUR7_OCHA4 ;  Q04EU0, PUR7_OENOB ;
DR   A7HWB4, PUR7_PARL1 ;  P57878, PUR7_PASMU ;  C6DBS2, PUR7_PECCP ;
DR   Q03E76, PUR7_PEDPA ;  Q3A5Q6, PUR7_PELCD ;  Q3B3M5, PUR7_PELLD ;
DR   B4SGP8, PUR7_PELPB ;  A1ATJ1, PUR7_PELPD ;  Q4FLJ7, PUR7_PELUB ;
DR   C0QUE7, PUR7_PERMH ;  B4RHH0, PUR7_PHEZH ;  Q7N3H3, PUR7_PHOLL ;
DR   Q96VP6, PUR7_PICAN ;  Q9C1J4, PUR7_PICPA ;  A1VU36, PUR7_POLNA ;
DR   Q122N0, PUR7_POLSJ ;  Q7MVR8, PUR7_PORGI ;  B4S8K9, PUR7_PROA2 ;
DR   A2C4B2, PUR7_PROM1 ;  A2C740, PUR7_PROM3 ;  A9BBW2, PUR7_PROM4 ;
DR   Q7VAN8, PUR7_PROMA ;  B4EY76, PUR7_PROMH ;  Q7V5X1, PUR7_PROMM ;
DR   Q7V0C7, PUR7_PROMP ;  Q46JC7, PUR7_PROMT ;  A4SE69, PUR7_PROVI ;
DR   Q48LD2, PUR7_PSE14 ;  Q15SZ6, PUR7_PSEA6 ;  A6V9K1, PUR7_PSEA7 ;
DR   B7UXT0, PUR7_PSEA8 ;  Q02IH8, PUR7_PSEAB ;  Q9I4W0, PUR7_PSEAE ;
DR   Q1I6H8, PUR7_PSEE4 ;  Q4KGP5, PUR7_PSEF5 ;  C3KED7, PUR7_PSEFS ;
DR   A5VZX1, PUR7_PSEP1 ;  Q3KGI9, PUR7_PSEPF ;  B0KSY0, PUR7_PSEPG ;
DR   Q88NG9, PUR7_PSEPK ;  B1JDB4, PUR7_PSEPW ;  Q87Y59, PUR7_PSESM ;
DR   Q4ZW72, PUR7_PSEU2 ;  Q4FVD4, PUR7_PSYA2 ;  Q1QEF9, PUR7_PSYCK ;
DR   A1SVX4, PUR7_PSYIN ;  A5WHC5, PUR7_PSYWF ;  Q9V254, PUR7_PYRAB ;
DR   Q8ZZK5, PUR7_PYRAE ;  A3MXE4, PUR7_PYRCJ ;  Q8U4D5, PUR7_PYRFU ;
DR   O57978, PUR7_PYRHO ;  Q5JFN5, PUR7_PYRKO ;  Q1LR36, PUR7_RALME ;
DR   Q8Y1W3, PUR7_RALSO ;  Q92PI3, PUR7_RHIME ;  C3MD65, PUR7_RHISN ;
DR   Q7UJ19, PUR7_RHOBA ;  B6IWP6, PUR7_RHOCS ;  C0ZRJ1, PUR7_RHOE4 ;
DR   Q222U2, PUR7_RHOFD ;  C1AT85, PUR7_RHOOB ;  Q0S784, PUR7_RHOSR ;
DR   C3PMR4, PUR7_RICAE ;  A8GML2, PUR7_RICAH ;  A8GVV0, PUR7_RICB8 ;
DR   Q1RJ49, PUR7_RICBR ;  A8EXW3, PUR7_RICCK ;  Q92IX6, PUR7_RICCN ;
DR   Q4UML8, PUR7_RICFE ;  A8F0X7, PUR7_RICM5 ;  O05946, PUR7_RICPR ;
DR   C4K0X5, PUR7_RICPU ;  B0BWM7, PUR7_RICRO ;  A8GR81, PUR7_RICRS ;
DR   Q68XE9, PUR7_RICTY ;  A7NKB4, PUR7_ROSCS ;  Q167J5, PUR7_ROSDO ;
DR   A5UWC5, PUR7_ROSS1 ;  Q21MZ8, PUR7_SACD2 ;  A4FQI3, PUR7_SACEN ;
DR   B5F0L3, PUR7_SALA4 ;  A8M3D4, PUR7_SALAI ;  A9MHQ4, PUR7_SALAR ;
DR   Q57LM4, PUR7_SALCH ;  B5FQH7, PUR7_SALDC ;  B5R4J4, PUR7_SALEP ;
DR   B5RCV7, PUR7_SALG2 ;  B4TD62, PUR7_SALHS ;  B4T0L4, PUR7_SALNS ;
DR   Q5PLR9, PUR7_SALPA ;  A9N2Z5, PUR7_SALPB ;  C0PYS1, PUR7_SALPC ;
DR   B5BB18, PUR7_SALPK ;  B4TR59, PUR7_SALSV ;  P65890, PUR7_SALTI ;
DR   A4XB58, PUR7_SALTO ;  P65889, PUR7_SALTY ;  Q9UUB4, PUR7_SCHPO ;
DR   A8GHL5, PUR7_SERP5 ;  A1S2U5, PUR7_SHEAM ;  B8E8I2, PUR7_SHEB2 ;
DR   A3D944, PUR7_SHEB5 ;  A6WIQ6, PUR7_SHEB8 ;  A9KZH0, PUR7_SHEB9 ;
DR   Q12JN5, PUR7_SHEDO ;  Q07WS1, PUR7_SHEFN ;  B0TQY6, PUR7_SHEHH ;
DR   Q8EA43, PUR7_SHEON ;  A8H5E7, PUR7_SHEPA ;  A4Y307, PUR7_SHEPC ;
DR   B8CR57, PUR7_SHEPW ;  A0L1C5, PUR7_SHESA ;  Q0HEK4, PUR7_SHESM ;
DR   Q0HZE8, PUR7_SHESR ;  A1RNX8, PUR7_SHESW ;  B2TXQ2, PUR7_SHIB3 ;
DR   Q31Y15, PUR7_SHIBS ;  Q32D90, PUR7_SHIDS ;  Q0T241, PUR7_SHIF8 ;
DR   P0A7E0, PUR7_SHIFL ;  Q3YZ76, PUR7_SHISS ;  Q5LS81, PUR7_SILPO ;
DR   A6U9L2, PUR7_SINMW ;  Q2NS76, PUR7_SODGM ;  Q1GVL7, PUR7_SPHAL ;
DR   A5V2F8, PUR7_SPHWW ;  A7X0V7, PUR7_STAA1 ;  A6U0N4, PUR7_STAA2 ;
DR   Q2FI12, PUR7_STAA3 ;  Q2FZJ3, PUR7_STAA8 ;  A5IRV3, PUR7_STAA9 ;
DR   Q2YX57, PUR7_STAAB ;  Q5HH18, PUR7_STAAC ;  A6QFS5, PUR7_STAAE ;
DR   P65891, PUR7_STAAM ;  P99064, PUR7_STAAN ;  Q6GI18, PUR7_STAAR ;
DR   Q6GAE7, PUR7_STAAS ;  A8Z1K8, PUR7_STAAT ;  P65892, PUR7_STAAW ;
DR   B9DQ35, PUR7_STACT ;  Q5HQA4, PUR7_STAEQ ;  Q8CPP1, PUR7_STAES ;
DR   Q4L575, PUR7_STAHJ ;  Q49WJ0, PUR7_STAS1 ;  Q3K403, PUR7_STRA1 ;
DR   Q8E7X2, PUR7_STRA3 ;  Q8E2G4, PUR7_STRA5 ;  Q82FV6, PUR7_STRAW ;
DR   Q9RKL1, PUR7_STRCO ;  C0MAG2, PUR7_STRE4 ;  B4U5E5, PUR7_STREM ;
DR   A8AU96, PUR7_STRGC ;  B1VR40, PUR7_STRGG ;  B4SLF7, PUR7_STRM5 ;
DR   B2FKM0, PUR7_STRMK ;  Q8DWL6, PUR7_STRMU ;  Q9A1Z3, PUR7_STRP1 ;
DR   Q04N25, PUR7_STRP2 ;  P0DD56, PUR7_STRP3 ;  B5E5J3, PUR7_STRP4 ;
DR   Q5XEF7, PUR7_STRP6 ;  C1C9U8, PUR7_STRP7 ;  Q8P315, PUR7_STRP8 ;
DR   B1I7V1, PUR7_STRPI ;  B8ZJM7, PUR7_STRPJ ;  Q07296, PUR7_STRPN ;
DR   P0DD57, PUR7_STRPQ ;  Q8DRM7, PUR7_STRR6 ;  C0MCA1, PUR7_STRS7 ;
DR   A3CJZ1, PUR7_STRSV ;  Q5M206, PUR7_STRT1 ;  Q5M6J8, PUR7_STRT2 ;
DR   Q03N01, PUR7_STRTD ;  B9DSR1, PUR7_STRU0 ;  C1CBM0, PUR7_STRZJ ;
DR   C1CHV6, PUR7_STRZP ;  C1CNS2, PUR7_STRZT ;  Q4J8G0, PUR7_SULAC ;
DR   Q30TB0, PUR7_SULDN ;  Q9UX20, PUR7_SULSO ;  Q970V9, PUR7_SULTO ;
DR   A0LHQ3, PUR7_SYNFM ;  Q2JXL8, PUR7_SYNJA ;  Q2JKP0, PUR7_SYNJB ;
DR   B1XNE9, PUR7_SYNP2 ;  A5GN71, PUR7_SYNPW ;  Q7U8Q9, PUR7_SYNPX ;
DR   Q0I808, PUR7_SYNS3 ;  Q3AZF6, PUR7_SYNS9 ;  Q3AHS3, PUR7_SYNSC ;
DR   P73471, PUR7_SYNY3 ;  Q9HLC0, PUR7_THEAC ;  Q8DIT5, PUR7_THEEB ;
DR   Q47KH4, PUR7_THEFY ;  Q9X0X0, PUR7_THEMA ;  A5IMW3, PUR7_THEP1 ;
DR   B0KBQ8, PUR7_THEP3 ;  B0K3Q1, PUR7_THEPX ;  C6A0I8, PUR7_THESM ;
DR   B1LCA5, PUR7_THESQ ;  Q8RC58, PUR7_THETN ;  Q978V1, PUR7_THEVO ;
DR   B5YFN3, PUR7_THEYD ;  B8GP39, PUR7_THISH ;  Q10VV0, PUR7_TRIEI ;
DR   Q83IB9, PUR7_TROW8 ;  Q83GX1, PUR7_TROWT ;  Q9KSR6, PUR7_VIBCH ;
DR   Q5E4Q3, PUR7_VIBF1 ;  B5FEP5, PUR7_VIBFM ;  A7MVN0, PUR7_VIBHB ;
DR   Q87Q87, PUR7_VIBPA ;  B7VMT0, PUR7_VIBSL ;  Q8D915, PUR7_VIBVU ;
DR   Q7MLF9, PUR7_VIBVY ;  Q07463, PUR7_VIGAC ;  Q8D2M4, PUR7_WIGBR ;
DR   Q73GD4, PUR7_WOLPM ;  B3CM64, PUR7_WOLPP ;  Q7M9X5, PUR7_WOLSU ;
DR   Q5GT56, PUR7_WOLTR ;  C0R444, PUR7_WOLWR ;  Q8PQ58, PUR7_XANAC ;
DR   Q3BYD2, PUR7_XANC5 ;  Q4UZH5, PUR7_XANC8 ;  B0RMY6, PUR7_XANCB ;
DR   Q8PD87, PUR7_XANCP ;  Q2NYP3, PUR7_XANOM ;  B2SM33, PUR7_XANOP ;
DR   Q5GVG5, PUR7_XANOR ;  B2I6R9, PUR7_XYLF2 ;  Q9PGU3, PUR7_XYLFA ;
DR   B0U1N3, PUR7_XYLFM ;  Q87EX9, PUR7_XYLFT ;  P27616, PUR7_YEAST ;
DR   A1JL09, PUR7_YERE8 ;  A7FG51, PUR7_YERP3 ;  Q1C5Q7, PUR7_YERPA ;
DR   B2K993, PUR7_YERPB ;  Q8ZCD2, PUR7_YERPE ;  A9R2H1, PUR7_YERPG ;
DR   Q1CK24, PUR7_YERPN ;  A4TMM9, PUR7_YERPP ;  Q668F9, PUR7_YERPS ;
DR   B1JSG7, PUR7_YERPY ;  Q5NNN4, PUR7_ZYMMO ;  Q54QE4, PURCE_DICDI;
//
ID   6.3.2.7
DE   UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase.
AN   L-lysine-adding enzyme.
AN   MurE synthetase.
AN   UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine synthetase.
AN   UPD-MurNAc-L-Ala-D-Glu:L-Lys ligase.
AN   Uridine diphospho-N-acetylmuramoylalanyl-D-glutamyllysine synthetase.
CA   ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + L-lysine = ADP +
CA   phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine.
CC   -!- Involved with EC 6.3.2.4, EC 6.3.2.8, EC 6.3.2.9 and EC 6.3.2.10 in
CC       the synthesis of a cell-wall peptide.
CC   -!- This enzyme adds lysine in some Gram-positive organisms; in others
CC       and in Gram-negative organisms EC 6.3.2.13 adds 2,6-diaminopimelate
CC       instead.
DR   Q838A4, MURE_ENTFA ;  A7X0P6, MURE_STAA1 ;  Q2FI59, MURE_STAA3 ;
DR   Q2FZP6, MURE_STAA8 ;  Q2YWY9, MURE_STAAB ;  O86491, MURE_STAAC ;
DR   P65479, MURE_STAAM ;  P65480, MURE_STAAN ;  Q6GI66, MURE_STAAR ;
DR   Q6GAQ9, MURE_STAAS ;  Q8NXC2, MURE_STAAW ;  Q5HQE6, MURE_STAEQ ;
DR   Q8CPR2, MURE_STAES ;  Q4L525, MURE_STAHJ ;  Q3K0C1, MURE_STRA1 ;
DR   Q8E4E0, MURE_STRA3 ;  Q8DYT2, MURE_STRA5 ;  Q8DST2, MURE_STRMU ;
DR   Q9A196, MURE_STRP1 ;  Q04JL8, MURE_STRP2 ;  P0DC54, MURE_STRP3 ;
DR   Q5XDM7, MURE_STRP6 ;  Q8P2B4, MURE_STRP8 ;  Q1JN87, MURE_STRPC ;
DR   Q1JID8, MURE_STRPD ;  Q1J890, MURE_STRPF ;  A2RG75, MURE_STRPG ;
DR   Q48V28, MURE_STRPM ;  Q97PS1, MURE_STRPN ;  P0DC55, MURE_STRPQ ;
DR   Q8CWQ5, MURE_STRR6 ;  A4W0C1, MURE_STRS2 ;  A3CPL6, MURE_STRSV ;
DR   A4VU28, MURE_STRSY ;  Q5M1B4, MURE_STRT1 ;  Q5M5V0, MURE_STRT2 ;
DR   Q03M85, MURE_STRTD ;  Q9WY79, MURE_THEMA ;
//
ID   6.3.2.8
DE   UDP-N-acetylmuramate--L-alanine ligase.
AN   Alanine-adding enzyme.
AN   L-Ala ligase.
AN   L-alanine-adding enzyme.
AN   MurC synthetase.
AN   UDP-acetylmuramyl-L-alanine synthetase.
AN   UDP-MurNAc:L-alanine ligase.
AN   UDP-N-acetylmuramoyl-L-alanine synthetase.
AN   UDP-N-acetylmuramoylalanine synthetase.
AN   UDP-N-acetylmuramyl:L-alanine ligase.
AN   UDPMurNAc-L-alanine synthetase.
AN   Uridine 5'-diphosphate-N-acetylmuramyl-L-alanine synthetase.
AN   Uridine diphosphate N-acetylmuramate:L-alanine ligase.
AN   Uridine diphospho-N-acetylmuramoylalanine synthetase.
AN   Uridine-diphosphate-N-acetylmuramate:L-alanine ligase.
CA   ATP + UDP-N-acetylmuramate + L-alanine = ADP + phosphate + UDP-N-
CA   acetylmuramoyl-L-alanine.
CC   -!- Involved with EC 6.3.2.4, EC 6.3.2.7 or EC 6.3.2.13, EC 6.3.2.9 and
CC       EC 6.3.2.10 in the synthesis of a cell-wall peptide.
PR   PROSITE; PDOC50975;
DR   Q821S4, MUDD_CHLCV ;  Q9PLG1, MUDD_CHLMU ;  Q9Z701, MUDD_CHLPN ;
DR   O84767, MUDD_CHLTR ;  B0CCD6, MURC_ACAM1 ;  A1TKD2, MURC_ACIAC ;
DR   Q6F704, MURC_ACIAD ;  B7GV74, MURC_ACIB3 ;  B7ICE4, MURC_ACIB5 ;
DR   B2I1J4, MURC_ACIBC ;  Q1IKH1, MURC_ACIBL ;  B0VNZ8, MURC_ACIBS ;
DR   A3M9Y0, MURC_ACIBT ;  B0V9F6, MURC_ACIBY ;  A0LTM4, MURC_ACIC1 ;
DR   C1F455, MURC_ACIC5 ;  A5FUL1, MURC_ACICJ ;  B9MFR1, MURC_ACIET ;
DR   B7J3V1, MURC_ACIF2 ;  B5ELC2, MURC_ACIF5 ;  A1WC05, MURC_ACISJ ;
DR   A3MY91, MURC_ACTP2 ;  B3GZK9, MURC_ACTP7 ;  B0BRH8, MURC_ACTPJ ;
DR   A6VQN2, MURC_ACTSZ ;  A0KPX1, MURC_AERHH ;  A4SI57, MURC_AERS4 ;
DR   Q8UDM9, MURC_AGRT5 ;  B9JY53, MURC_AGRVS ;  Q0VS01, MURC_ALCBS ;
DR   Q0A6K3, MURC_ALHEH ;  B6ELH4, MURC_ALISL ;  A6TJM2, MURC_ALKMQ ;
DR   A8MK48, MURC_ALKOO ;  B8J8E9, MURC_ANAD2 ;  Q2IG30, MURC_ANADE ;
DR   A7HH68, MURC_ANADF ;  B4UES2, MURC_ANASK ;  B9MND8, MURC_ANATD ;
DR   Q3MAP8, MURC_ANAVT ;  B7GK78, MURC_ANOFW ;  O67373, MURC_AQUAE ;
DR   Q5P6Z7, MURC_AROAE ;  A1R5F9, MURC_ARTAT ;  A0JV95, MURC_ARTS2 ;
DR   A8HZ95, MURC_AZOC5 ;  A1K3U7, MURC_AZOSB ;  C1DQA0, MURC_AZOVD ;
DR   A7Z7S3, MURC_BACA2 ;  C3PBF0, MURC_BACAA ;  C3L9Z3, MURC_BACAC ;
DR   A0RJS6, MURC_BACAH ;  Q81KQ2, MURC_BACAN ;  B7JS63, MURC_BACC0 ;
DR   P61675, MURC_BACC1 ;  B7IKV4, MURC_BACC2 ;  C1EV43, MURC_BACC3 ;
DR   B7H746, MURC_BACC4 ;  B7HSM3, MURC_BACC7 ;  A7GTV6, MURC_BACCN ;
DR   B9J189, MURC_BACCQ ;  Q816X6, MURC_BACCR ;  Q633A2, MURC_BACCZ ;
DR   Q9K7W1, MURC_BACHD ;  Q6HCJ2, MURC_BACHK ;  Q65G22, MURC_BACLD ;
DR   A8FGB7, MURC_BACP2 ;  Q5WEA8, MURC_BACSK ;  P40778, MURC_BACSU ;
DR   A6L070, MURC_BACV8 ;  A9VKJ7, MURC_BACWK ;  A1UTC4, MURC_BARBK ;
DR   Q6G2Q6, MURC_BARHE ;  Q6G125, MURC_BARQU ;  A9IWA4, MURC_BART1 ;
DR   Q1LSW6, MURC_BAUCH ;  P61676, MURC_BDEBA ;  B2IGG1, MURC_BEII9 ;
DR   A1A2E8, MURC_BIFAA ;  B3DQN2, MURC_BIFLD ;  Q8G4Q4, MURC_BIFLO ;
DR   B7GQ79, MURC_BIFLS ;  Q7VQI7, MURC_BLOFL ;  Q493Q0, MURC_BLOPB ;
DR   Q2KVG1, MURC_BORA1 ;  Q0SM34, MURC_BORAP ;  Q7WFS3, MURC_BORBR ;
DR   O51757, MURC_BORBU ;  Q65ZV7, MURC_BORGA ;  Q7W4B5, MURC_BORPA ;
DR   A9I4V6, MURC_BORPD ;  Q7VUQ4, MURC_BORPE ;  C0QXF2, MURC_BRAHW ;
DR   Q89FU8, MURC_BRAJA ;  A5EPK1, MURC_BRASB ;  A4YZK2, MURC_BRASO ;
DR   C0ZAJ4, MURC_BREBN ;  B2S6Q3, MURC_BRUA1 ;  Q2YLY6, MURC_BRUA2 ;
DR   Q57C79, MURC_BRUAB ;  A9M689, MURC_BRUC2 ;  C0RE69, MURC_BRUMB ;
DR   P65468, MURC_BRUME ;  A5VRH6, MURC_BRUO2 ;  B0CHL9, MURC_BRUSI ;
DR   P65469, MURC_BRUSU ;  B8D913, MURC_BUCA5 ;  P57310, MURC_BUCAI ;
DR   O51926, MURC_BUCAP ;  B8D7B8, MURC_BUCAT ;  P59418, MURC_BUCBP ;
DR   B1YSS5, MURC_BURA4 ;  Q1BZG2, MURC_BURCA ;  B1JV79, MURC_BURCC ;
DR   A0K487, MURC_BURCH ;  B4E6J1, MURC_BURCJ ;  Q0BIK0, MURC_BURCM ;
DR   A9AI95, MURC_BURM1 ;  A3MR64, MURC_BURM7 ;  A2S5U4, MURC_BURM9 ;
DR   Q62GS8, MURC_BURMA ;  A1V0R7, MURC_BURMS ;  A3NZL4, MURC_BURP0 ;
DR   Q3JND9, MURC_BURP1 ;  A3NDW3, MURC_BURP6 ;  B2JHF9, MURC_BURP8 ;
DR   B2SYX4, MURC_BURPP ;  Q63QJ8, MURC_BURPS ;  Q39JW9, MURC_BURS3 ;
DR   Q2SZI2, MURC_BURTA ;  A4JB95, MURC_BURVG ;  Q13TZ3, MURC_BURXL ;
DR   A4XGE5, MURC_CALS8 ;  A7GX33, MURC_CAMC5 ;  A8FMA8, MURC_CAMJ8 ;
DR   A7H2V3, MURC_CAMJD ;  Q9PNN7, MURC_CAMJE ;  A1W043, MURC_CAMJJ ;
DR   Q5HU47, MURC_CAMJR ;  Q3AAE7, MURC_CARHZ ;  B8H086, MURC_CAUCN ;
DR   Q9A5A6, MURC_CAUCR ;  B0T827, MURC_CAUSK ;  A9WG70, MURC_CHLAA ;
DR   B8G5Y3, MURC_CHLAD ;  Q3ANV2, MURC_CHLCH ;  B3EIK7, MURC_CHLL2 ;
DR   B3QLW3, MURC_CHLP8 ;  B3EQB7, MURC_CHLPB ;  A1BJX7, MURC_CHLPD ;
DR   Q8KGD5, MURC_CHLTE ;  Q1QVG8, MURC_CHRSD ;  Q7NQ00, MURC_CHRVO ;
DR   A8ALK5, MURC_CITK8 ;  A5CS50, MURC_CLAM3 ;  B0RIJ4, MURC_CLAMS ;
DR   Q97E89, MURC_CLOAB ;  A7FPH5, MURC_CLOB1 ;  C3KWA4, MURC_CLOB6 ;
DR   A6LPI8, MURC_CLOB8 ;  B2UXS3, MURC_CLOBA ;  B2TI04, MURC_CLOBB ;
DR   A5I7S3, MURC_CLOBH ;  C1FNF4, MURC_CLOBJ ;  B1IH05, MURC_CLOBK ;
DR   A7GJE2, MURC_CLOBL ;  B1KTF0, MURC_CLOBM ;  Q181B7, MURC_CLOD6 ;
DR   B9DY44, MURC_CLOK1 ;  A5N4I2, MURC_CLOK5 ;  A0PXK5, MURC_CLONN ;
DR   Q0TMG0, MURC_CLOP1 ;  Q8XHJ0, MURC_CLOPE ;  A9KQI8, MURC_CLOPH ;
DR   Q0SQ58, MURC_CLOPS ;  Q899J1, MURC_CLOTE ;  A3DIP6, MURC_CLOTH ;
DR   Q47VR0, MURC_COLP3 ;  C3PHF5, MURC_CORA7 ;  P61677, MURC_CORDI ;
DR   Q8FNU1, MURC_COREF ;  A4QFM2, MURC_CORGB ;  P94335, MURC_CORGL ;
DR   Q4JW94, MURC_CORJK ;  B1VHC3, MURC_CORU7 ;  B6J5K2, MURC_COXB1 ;
DR   B6J2Q2, MURC_COXB2 ;  A9KER2, MURC_COXBN ;  A9NA45, MURC_COXBR ;
DR   Q83F17, MURC_COXBU ;  Q0K6M5, MURC_CUPNH ;  Q46WZ5, MURC_CUPPJ ;
DR   B3R6V8, MURC_CUPTR ;  B1WQL2, MURC_CYAA5 ;  B8HWY0, MURC_CYAP4 ;
DR   B7KHE9, MURC_CYAP7 ;  Q11RH6, MURC_CYTH3 ;  Q47AA5, MURC_DECAR ;
DR   Q1IXV8, MURC_DEIGD ;  Q9RWN9, MURC_DEIRA ;  A9BUK7, MURC_DELAS ;
DR   B8FBR7, MURC_DESAA ;  C6BYG5, MURC_DESAD ;  C0Q8P4, MURC_DESAH ;
DR   B8IZU2, MURC_DESDA ;  Q313Q2, MURC_DESDG ;  Q24ZG1, MURC_DESHY ;
DR   C4XK68, MURC_DESMR ;  A8ZXW2, MURC_DESOH ;  Q6AJ54, MURC_DESPS ;
DR   A4J2B2, MURC_DESRM ;  P61678, MURC_DESVH ;  A1VBE9, MURC_DESVV ;
DR   A5EY22, MURC_DICNV ;  B5YEL2, MURC_DICT6 ;  B8E324, MURC_DICTD ;
DR   A8LS63, MURC_DINSH ;  A7ZHI2, MURC_ECO24 ;  B7UIE1, MURC_ECO27 ;
DR   B7MAL4, MURC_ECO45 ;  B7LFW1, MURC_ECO55 ;  P65471, MURC_ECO57 ;
DR   B5YZC7, MURC_ECO5E ;  B7NHJ7, MURC_ECO7I ;  B7MNV0, MURC_ECO81 ;
DR   B7M134, MURC_ECO8A ;  C4ZRI6, MURC_ECOBW ;  B1XC68, MURC_ECODH ;
DR   A7ZW43, MURC_ECOHS ;  A1A7D6, MURC_ECOK1 ;  Q0TLP8, MURC_ECOL5 ;
DR   P65470, MURC_ECOL6 ;  B1IR87, MURC_ECOLC ;  P17952, MURC_ECOLI ;
DR   B7N7W4, MURC_ECOLU ;  B6HZ68, MURC_ECOSE ;  B1LG28, MURC_ECOSM ;
DR   Q1RGA4, MURC_ECOUT ;  A4W6J4, MURC_ENT38 ;  Q833N6, MURC_ENTFA ;
DR   A7MIF0, MURC_ENTS8 ;  Q6D0I4, MURC_ERWCT ;  Q2NCY9, MURC_ERYLH ;
DR   B7LWF7, MURC_ESCF3 ;  C4Z4L9, MURC_EUBE2 ;  C4ZBV1, MURC_EUBR3 ;
DR   B1YKE8, MURC_EXIS2 ;  C4L4P1, MURC_EXISA ;  A5FIY4, MURC_FLAJ1 ;
DR   A6H194, MURC_FLAPJ ;  Q0RNN9, MURC_FRAAA ;  B0TW67, MURC_FRAP2 ;
DR   Q2JD48, MURC_FRASC ;  Q14JK2, MURC_FRAT1 ;  A7N9L2, MURC_FRATF ;
DR   Q2A5N4, MURC_FRATH ;  B2SE51, MURC_FRATM ;  A0Q425, MURC_FRATN ;
DR   Q5NI50, MURC_FRATT ;  A4J011, MURC_FRATW ;  Q8RDQ2, MURC_FUSNN ;
DR   B5EBQ2, MURC_GEOBB ;  Q5KW36, MURC_GEOKA ;  B3E3Y1, MURC_GEOLS ;
DR   Q39YL8, MURC_GEOMG ;  B9M173, MURC_GEOSF ;  P61679, MURC_GEOSL ;
DR   C6DZK7, MURC_GEOSM ;  C5D6B2, MURC_GEOSW ;  A4IRW1, MURC_GEOTN ;
DR   A5G8J9, MURC_GEOUR ;  Q7NI67, MURC_GLOVI ;  A9H0J3, MURC_GLUDA ;
DR   Q5FUJ4, MURC_GLUOX ;  Q0BV26, MURC_GRABC ;  A0M526, MURC_GRAFK ;
DR   Q7VMY1, MURC_HAEDU ;  Q4QLF7, MURC_HAEI8 ;  A5UCW7, MURC_HAEIE ;
DR   A5UIR3, MURC_HAEIG ;  P45066, MURC_HAEIN ;  B8F3B7, MURC_HAEPS ;
DR   Q0I1D2, MURC_HAES1 ;  B0US68, MURC_HAES2 ;  Q2S9Z3, MURC_HAHCH ;
DR   A1WYU2, MURC_HALHL ;  C4K735, MURC_HAMD5 ;  B6JLL1, MURC_HELP2 ;
DR   Q1CTP9, MURC_HELPH ;  Q9ZLL2, MURC_HELPJ ;  B2UTK2, MURC_HELPS ;
DR   O25340, MURC_HELPY ;  A4G8T7, MURC_HERAR ;  B4U813, MURC_HYDS0 ;
DR   Q0BXU4, MURC_HYPNA ;  Q5R0M0, MURC_IDILO ;  A6T2F7, MURC_JANMA ;
DR   Q28NN6, MURC_JANSC ;  A6WCX3, MURC_KINRD ;  B5Y1U6, MURC_KLEP3 ;
DR   A6T4N4, MURC_KLEP7 ;  Q5FIS8, MURC_LACAC ;  Q03RJ2, MURC_LACBA ;
DR   Q037Y8, MURC_LACC3 ;  B3WF58, MURC_LACCB ;  Q1G9A0, MURC_LACDA ;
DR   Q049E9, MURC_LACDB ;  B2GDC4, MURC_LACF3 ;  Q041T4, MURC_LACGA ;
DR   A8YWG1, MURC_LACH4 ;  P61680, MURC_LACJO ;  Q9CE10, MURC_LACLA ;
DR   A2RNJ0, MURC_LACLM ;  Q02W92, MURC_LACLS ;  Q88WZ5, MURC_LACPL ;
DR   A5VKY3, MURC_LACRD ;  Q1WUP1, MURC_LACS1 ;  Q38XY8, MURC_LACSS ;
DR   C1D5L5, MURC_LARHH ;  Q1MPB8, MURC_LAWIP ;  Q5X1S6, MURC_LEGPA ;
DR   A5IAW2, MURC_LEGPC ;  Q5ZSA5, MURC_LEGPH ;  Q5WTI7, MURC_LEGPL ;
DR   Q6AE65, MURC_LEIXX ;  B1XYR4, MURC_LEPCP ;  B1MZK4, MURC_LEUCK ;
DR   Q03YA3, MURC_LEUMM ;  Q92BA4, MURC_LISIN ;  C1KVQ2, MURC_LISMC ;
DR   Q71Z62, MURC_LISMF ;  B8DHD7, MURC_LISMH ;  Q8Y6S8, MURC_LISMO ;
DR   A0AJ57, MURC_LISW6 ;  B1HX90, MURC_LYSSC ;  B9E7F6, MURC_MACCJ ;
DR   Q2W0H2, MURC_MAGSA ;  A0L5N0, MURC_MAGSM ;  Q65RY7, MURC_MANSM ;
DR   A1U3F7, MURC_MARAV ;  Q0AMW8, MURC_MARMM ;  A6VYJ7, MURC_MARMS ;
DR   Q11GS6, MURC_MESSB ;  B7KSC2, MURC_METC4 ;  Q604V8, MURC_METCA ;
DR   A9VWV4, MURC_METEP ;  Q1GZ02, MURC_METFK ;  B8IN63, MURC_METNO ;
DR   B1ZGP5, MURC_METPB ;  A2SCY6, MURC_METPP ;  B1LXZ3, MURC_METRJ ;
DR   B0UFC6, MURC_METS4 ;  B8ETM5, MURC_METSB ;  B0JHH4, MURC_MICAN ;
DR   Q2RK78, MURC_MOOTA ;  A0QF53, MURC_MYCA1 ;  B1MP38, MURC_MYCA9 ;
DR   P65473, MURC_MYCBO ;  A1KKJ5, MURC_MYCBP ;  C1AQ68, MURC_MYCBT ;
DR   A4TBE7, MURC_MYCGI ;  B8ZQQ1, MURC_MYCLB ;  P57994, MURC_MYCLE ;
DR   B2HGR5, MURC_MYCMM ;  P61681, MURC_MYCPA ;  A0R015, MURC_MYCS2 ;
DR   A3Q1L7, MURC_MYCSJ ;  A1UI53, MURC_MYCSK ;  Q1B6X2, MURC_MYCSS ;
DR   A5U4H9, MURC_MYCTA ;  P65472, MURC_MYCTU ;  A0PTI6, MURC_MYCUA ;
DR   A1TAW7, MURC_MYCVP ;  Q1D0T1, MURC_MYXXD ;  Q5F6L9, MURC_NEIG1 ;
DR   A9M2H2, MURC_NEIM0 ;  Q9JSZ8, MURC_NEIMA ;  Q9K0Y1, MURC_NEIMB ;
DR   A1KVL2, MURC_NEIMF ;  Q0AJE2, MURC_NITEC ;  Q82VS2, MURC_NITEU ;
DR   Q1QNU2, MURC_NITHX ;  Q2Y639, MURC_NITMU ;  Q3J790, MURC_NITOC ;
DR   Q3STS7, MURC_NITWN ;  Q5YYX8, MURC_NOCFA ;  A1SL79, MURC_NOCSJ ;
DR   B2J717, MURC_NOSP7 ;  Q8YM75, MURC_NOSS1 ;  Q2G994, MURC_NOVAD ;
DR   Q8EP84, MURC_OCEIH ;  A6WZQ7, MURC_OCHA4 ;  Q04EI0, MURC_OENOB ;
DR   A5CD22, MURC_ORITB ;  A6LEU2, MURC_PARD8 ;  A1BAL4, MURC_PARDP ;
DR   A7HVU8, MURC_PARL1 ;  Q6MBS8, MURC_PARUW ;  P57818, MURC_PASMU ;
DR   C6DEU2, MURC_PECCP ;  Q03GC5, MURC_PEDPA ;  Q3A2G7, MURC_PELCD ;
DR   Q3B130, MURC_PELLD ;  B4SH48, MURC_PELPB ;  A1AU60, MURC_PELPD ;
DR   A5D144, MURC_PELTS ;  Q4FPK6, MURC_PELUB ;  C0QPY2, MURC_PERMH ;
DR   B4RFG2, MURC_PHEZH ;  Q7N148, MURC_PHOLL ;  Q6LMF7, MURC_PHOPR ;
DR   A1VST5, MURC_POLNA ;  B1XT10, MURC_POLNS ;  Q12EL4, MURC_POLSJ ;
DR   A4SV75, MURC_POLSQ ;  B2RIF2, MURC_PORG3 ;  Q51831, MURC_PORGI ;
DR   B4S6Q8, MURC_PROA2 ;  Q6A9Q1, MURC_PROAC ;  A2BZC5, MURC_PROM1 ;
DR   A2C5M3, MURC_PROM3 ;  Q7VEJ1, MURC_PROMA ;  B4F110, MURC_PROMH ;
DR   Q7V9C3, MURC_PROMM ;  Q7V3P8, MURC_PROMP ;  Q46I40, MURC_PROMT ;
DR   A4SH01, MURC_PROVI ;  Q48EF9, MURC_PSE14 ;  Q15Q18, MURC_PSEA6 ;
DR   A6VB84, MURC_PSEA7 ;  B7UZI9, MURC_PSEA8 ;  Q02H29, MURC_PSEAB ;
DR   Q9HW02, MURC_PSEAE ;  Q1I5B9, MURC_PSEE4 ;  Q4K6J4, MURC_PSEF5 ;
DR   C3KCT1, MURC_PSEFS ;  Q3IFY1, MURC_PSEHT ;  A4XQS5, MURC_PSEMY ;
DR   A5W8P9, MURC_PSEP1 ;  Q3K745, MURC_PSEPF ;  B0KFS5, MURC_PSEPG ;
DR   Q88N75, MURC_PSEPK ;  B1J3L3, MURC_PSEPW ;  Q87WY6, MURC_PSESM ;
DR   Q4ZNZ1, MURC_PSEU2 ;  A4VIH9, MURC_PSEU5 ;  Q4FQW0, MURC_PSYA2 ;
DR   Q1Q945, MURC_PSYCK ;  A1SU20, MURC_PSYIN ;  A5WCT9, MURC_PSYWF ;
DR   Q1LIM7, MURC_RALME ;  B2UCX6, MURC_RALPJ ;  Q8XVI8, MURC_RALSO ;
DR   A9WRD7, MURC_RENSM ;  Q2K6C2, MURC_RHIEC ;  Q1ME34, MURC_RHIL3 ;
DR   Q98KB4, MURC_RHILO ;  Q92NM0, MURC_RHIME ;  C3MEM8, MURC_RHISN ;
DR   B6IRG1, MURC_RHOCS ;  C1A0X4, MURC_RHOE4 ;  Q21SX0, MURC_RHOFD ;
DR   C1AU54, MURC_RHOOB ;  Q2IYK6, MURC_RHOP2 ;  Q07PT2, MURC_RHOP5 ;
DR   P61682, MURC_RHOPA ;  Q211T9, MURC_RHOPB ;  Q133X2, MURC_RHOPS ;
DR   B3QFN0, MURC_RHOPT ;  Q2RVU5, MURC_RHORT ;  A3PHS9, MURC_RHOS1 ;
DR   Q3J4M1, MURC_RHOS4 ;  A4WQD6, MURC_RHOS5 ;  B9KNK0, MURC_RHOSK ;
DR   Q0SHS2, MURC_RHOSR ;  C3PMU4, MURC_RICAE ;  A8GMP6, MURC_RICAH ;
DR   A8GW94, MURC_RICB8 ;  Q1RHX0, MURC_RICBR ;  A8EXZ6, MURC_RICCK ;
DR   Q92IT9, MURC_RICCN ;  Q4UKN9, MURC_RICFE ;  A8F108, MURC_RICM5 ;
DR   Q9ZDS8, MURC_RICPR ;  C4K124, MURC_RICPU ;  B0BWS0, MURC_RICRO ;
DR   A8GRB9, MURC_RICRS ;  Q68XC2, MURC_RICTY ;  A7NI92, MURC_ROSCS ;
DR   Q163J1, MURC_ROSDO ;  A5UZT9, MURC_ROSS1 ;  Q1AVX4, MURC_RUBXD ;
DR   A1AX27, MURC_RUTMC ;  Q21MG8, MURC_SACD2 ;  A4FLV9, MURC_SACEN ;
DR   B5F7W5, MURC_SALA4 ;  A8LX80, MURC_SALAI ;  A9MQC1, MURC_SALAR ;
DR   Q57TC9, MURC_SALCH ;  B5FI73, MURC_SALDC ;  B5R2M5, MURC_SALEP ;
DR   B5RH65, MURC_SALG2 ;  B4TJ88, MURC_SALHS ;  B4SU51, MURC_SALNS ;
DR   Q5PDC7, MURC_SALPA ;  A9MZM0, MURC_SALPB ;  C0Q5I7, MURC_SALPC ;
DR   B5BLC3, MURC_SALPK ;  Q2S527, MURC_SALRD ;  B4TXH9, MURC_SALSV ;
DR   Q8Z9G8, MURC_SALTI ;  A4X9R5, MURC_SALTO ;  Q8ZRU2, MURC_SALTY ;
DR   A8G9S8, MURC_SERP5 ;  A1S2G0, MURC_SHEAM ;  B8E699, MURC_SHEB2 ;
DR   A3CZM2, MURC_SHEB5 ;  A6WID2, MURC_SHEB8 ;  A9KY30, MURC_SHEB9 ;
DR   Q12SC5, MURC_SHEDO ;  Q07WI6, MURC_SHEFN ;  B0TQN8, MURC_SHEHH ;
DR   A3QIM0, MURC_SHELP ;  Q8E9P8, MURC_SHEON ;  A8H983, MURC_SHEPA ;
DR   A4Y2N7, MURC_SHEPC ;  B8CNL2, MURC_SHEPW ;  A0L1P1, MURC_SHESA ;
DR   A8FQA1, MURC_SHESH ;  Q0HE84, MURC_SHESM ;  Q0HZR5, MURC_SHESR ;
DR   A1REZ7, MURC_SHESW ;  Q9F1M9, MURC_SHEVD ;  B1KKX6, MURC_SHEWM ;
DR   B2U296, MURC_SHIB3 ;  Q326E4, MURC_SHIBS ;  Q32K01, MURC_SHIDS ;
DR   Q0T8A6, MURC_SHIF8 ;  Q83MF8, MURC_SHIFL ;  Q3Z5R8, MURC_SHISS ;
DR   Q5LU62, MURC_SILPO ;  Q1GIV0, MURC_SILST ;  A6UB84, MURC_SINMW ;
DR   Q2NVV0, MURC_SODGM ;  Q01Q49, MURC_SOLUE ;  A9FI59, MURC_SORC5 ;
DR   Q1GRY0, MURC_SPHAL ;  A5VDC5, MURC_SPHWW ;  A7X3H5, MURC_STAA1 ;
DR   A6U2K6, MURC_STAA2 ;  Q2FFZ8, MURC_STAA3 ;  Q2FXJ0, MURC_STAA8 ;
DR   A5ITR2, MURC_STAA9 ;  Q5HF34, MURC_STAAC ;  A6QHS3, MURC_STAAE ;
DR   P65474, MURC_STAAM ;  P65475, MURC_STAAN ;  Q6GFW8, MURC_STAAR ;
DR   Q6G8I7, MURC_STAAS ;  A8Z4G7, MURC_STAAT ;  O31211, MURC_STAAU ;
DR   P65476, MURC_STAAW ;  B9DN57, MURC_STACT ;  Q5HNG9, MURC_STAEQ ;
DR   Q8CS47, MURC_STAES ;  Q4L784, MURC_STAHJ ;  Q49YH1, MURC_STAS1 ;
DR   Q3JZS0, MURC_STRA1 ;  Q8E3U2, MURC_STRA3 ;  Q8DY77, MURC_STRA5 ;
DR   Q82L07, MURC_STRAW ;  Q9X827, MURC_STRCO ;  C0M809, MURC_STRE4 ;
DR   B4U4S2, MURC_STREM ;  A8AVM1, MURC_STRGC ;  B1VWF9, MURC_STRGG ;
DR   B4SJX6, MURC_STRM5 ;  B2FNN8, MURC_STRMK ;  Q8DSP4, MURC_STRMU ;
DR   Q9A1C7, MURC_STRP1 ;  Q04HS5, MURC_STRP2 ;  P0DC50, MURC_STRP3 ;
DR   B5E685, MURC_STRP4 ;  Q5XDR0, MURC_STRP6 ;  C1C8B2, MURC_STRP7 ;
DR   Q8P2E1, MURC_STRP8 ;  Q1JDE8, MURC_STRPB ;  Q1JNC1, MURC_STRPC ;
DR   Q1JIH1, MURC_STRPD ;  Q1J8C6, MURC_STRPF ;  A2RGA7, MURC_STRPG ;
DR   B1ICU3, MURC_STRPI ;  B8ZLC2, MURC_STRPJ ;  Q48V60, MURC_STRPM ;
DR   Q97PS8, MURC_STRPN ;  P0DC51, MURC_STRPQ ;  B2IQY8, MURC_STRPS ;
DR   B5XJW3, MURC_STRPZ ;  Q8DP40, MURC_STRR6 ;  A4W3F1, MURC_STRS2 ;
DR   C0MGF5, MURC_STRS7 ;  A3CPS7, MURC_STRSV ;  A4VX47, MURC_STRSY ;
DR   Q5M1J9, MURC_STRT1 ;  Q5M641, MURC_STRT2 ;  Q03MH6, MURC_STRTD ;
DR   C1CFA5, MURC_STRZJ ;  C1CLL9, MURC_STRZP ;  C1CSE1, MURC_STRZT ;
DR   B2VA52, MURC_SULSY ;  Q67K97, MURC_SYMTH ;  Q2LR47, MURC_SYNAS ;
DR   P95836, MURC_SYNE7 ;  A0LNY9, MURC_SYNFM ;  Q2JTH3, MURC_SYNJA ;
DR   Q2JL88, MURC_SYNJB ;  Q5MZI0, MURC_SYNP6 ;  A5GHN9, MURC_SYNPW ;
DR   Q7UA71, MURC_SYNPX ;  A5GPX1, MURC_SYNR3 ;  Q0IE55, MURC_SYNS3 ;
DR   Q3B0X8, MURC_SYNS9 ;  Q3ANM4, MURC_SYNSC ;  Q0AYQ7, MURC_SYNWW ;
DR   P74528, MURC_SYNY3 ;  C5BP33, MURC_TERTT ;  Q8DLV5, MURC_THEEB ;
DR   Q47QW8, MURC_THEFY ;  A8F4X2, MURC_THELT ;  Q9WY73, MURC_THEMA ;
DR   B9K6P8, MURC_THENN ;  A5IKJ0, MURC_THEP1 ;  B1L9S2, MURC_THESQ ;
DR   Q8R749, MURC_THETN ;  Q31I43, MURC_THICR ;  Q3SMH2, MURC_THIDA ;
DR   C4LA26, MURC_TOLAT ;  O83361, MURC_TREPA ;  B2S2T8, MURC_TREPS ;
DR   Q10XH7, MURC_TRIEI ;  B1GYM8, MURC_UNCTG ;  C5CNF5, MURC_VARPS ;
DR   A1WRL2, MURC_VEREI ;  A5CW53, MURC_VESOH ;  A5F5M8, MURC_VIBC3 ;
DR   Q9KPG8, MURC_VIBCH ;  Q5E2Q1, MURC_VIBF1 ;  B5FB34, MURC_VIBFM ;
DR   A7MXR2, MURC_VIBHB ;  Q87SG3, MURC_VIBPA ;  B7VJ04, MURC_VIBSL ;
DR   Q8DEL1, MURC_VIBVU ;  Q7MNV0, MURC_VIBVY ;  Q8D2Z7, MURC_WIGBR ;
DR   P61683, MURC_WOLPM ;  Q5GTG5, MURC_WOLTR ;  C0R5N3, MURC_WOLWR ;
DR   Q8PPA7, MURC_XANAC ;  Q3BXF1, MURC_XANC5 ;  Q4UQX1, MURC_XANC8 ;
DR   B0RVA4, MURC_XANCB ;  Q8PCJ9, MURC_XANCP ;  Q2NZB9, MURC_XANOM ;
DR   B2SNZ4, MURC_XANOP ;  Q5GW42, MURC_XANOR ;  A7IEJ8, MURC_XANP2 ;
DR   B2I9B2, MURC_XYLF2 ;  Q9PF80, MURC_XYLFA ;  B0U4Z6, MURC_XYLFM ;
DR   Q87AG0, MURC_XYLFT ;  A1JJJ4, MURC_YERE8 ;  A7FM65, MURC_YERP3 ;
DR   Q1C215, MURC_YERPA ;  Q8ZIE8, MURC_YERPE ;  Q1CMM6, MURC_YERPN ;
DR   A4TQ82, MURC_YERPP ;  Q66EK4, MURC_YERPS ;  Q9RNM7, MURC_ZYMMO ;
//
ID   6.3.2.9
DE   UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase.
AN   D-glutamate ligase.
AN   D-glutamate-adding enzyme.
AN   MurD synthetase.
AN   UDP-Mur-NAC-L-Ala:D-Glu ligase.
AN   UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
AN   UDP-N-acetylmuramoylalanine--D-glutamate ligase.
AN   Uridine diphospho-N-acetylmuramoylalanyl-D-glutamate synthetase.
CA   ATP + UDP-N-acetylmuramoyl-L-alanine + glutamate = ADP + phosphate + UDP-
CA   N-acetylmuramoyl-L-alanyl-D-glutamate.
CC   -!- Involved with EC 6.3.2.4, EC 6.3.2.7 or EC 6.3.2.13, EC 6.3.2.8 and
CC       EC 6.3.2.10 in the synthesis of a cell-wall peptide.
DR   B0C915, MURD_ACAM1 ;  Q6FFC2, MURD_ACIAD ;  B7H1N2, MURD_ACIB3 ;
DR   B7I325, MURD_ACIB5 ;  B2I1V6, MURD_ACIBC ;  Q1IKG8, MURD_ACIBL ;
DR   A3M1C6, MURD_ACIBT ;  C1F460, MURD_ACIC5 ;  Q8UDM6, MURD_AGRT5 ;
DR   Q0VS04, MURD_ALCBS ;  B6ELH7, MURD_ALISL ;  A6TS63, MURD_ALKMQ ;
DR   A8MH34, MURD_ALKOO ;  Q2IG29, MURD_ANADE ;  Q5PBH9, MURD_ANAMM ;
DR   B9MQ99, MURD_ANATD ;  Q3MF19, MURD_ANAVT ;  O67852, MURD_AQUAE ;
DR   Q5P6Z4, MURD_AROAE ;  A7Z4E3, MURD_BACA2 ;  C3P682, MURD_BACAA ;
DR   C3L713, MURD_BACAC ;  A0RHT3, MURD_BACAH ;  Q81WC9, MURD_BACAN ;
DR   B7JK00, MURD_BACC0 ;  Q732F6, MURD_BACC1 ;  B7IUS2, MURD_BACC2 ;
DR   C1EPS6, MURD_BACC3 ;  B7H6P8, MURD_BACC4 ;  B7HM33, MURD_BACC7 ;
DR   A7GRN8, MURD_BACCN ;  B9IVY9, MURD_BACCQ ;  Q819Q2, MURD_BACCR ;
DR   Q636B4, MURD_BACCZ ;  Q5LIJ5, MURD_BACFN ;  Q64ZL9, MURD_BACFR ;
DR   Q9K9S8, MURD_BACHD ;  Q6HEQ2, MURD_BACHK ;  Q65JY2, MURD_BACLD ;
DR   A8FCX9, MURD_BACP2 ;  Q5WFG8, MURD_BACSK ;  Q03522, MURD_BACSU ;
DR   Q8A256, MURD_BACTN ;  A9VU74, MURD_BACWK ;  Q6G2Q3, MURD_BARHE ;
DR   Q6G122, MURD_BARQU ;  Q1LSW4, MURD_BAUCH ;  Q6MIF8, MURD_BDEBA ;
DR   A1A2F1, MURD_BIFAA ;  B3DQM9, MURD_BIFLD ;  Q8G4Q6, MURD_BIFLO ;
DR   B7GQ76, MURD_BIFLS ;  Q7VQI9, MURD_BLOFL ;  Q493Q3, MURD_BLOPB ;
DR   Q2KVF5, MURD_BORA1 ;  Q0SMS3, MURD_BORAP ;  Q7WFS0, MURD_BORBR ;
DR   O51532, MURD_BORBU ;  B7J2E8, MURD_BORBZ ;  Q7W4B2, MURD_BORPA ;
DR   Q7VUQ1, MURD_BORPE ;  Q89FU5, MURD_BRAJA ;  Q2YM69, MURD_BRUA2 ;
DR   Q57C76, MURD_BRUAB ;  Q8YI68, MURD_BRUME ;  Q8FZP2, MURD_BRUSU ;
DR   B8D916, MURD_BUCA5 ;  P57313, MURD_BUCAI ;  Q8K9T2, MURD_BUCAP ;
DR   B8D7C1, MURD_BUCAT ;  Q89AQ2, MURD_BUCBP ;  B1YSS2, MURD_BURA4 ;
DR   Q1BZG5, MURD_BURCA ;  B1JV76, MURD_BURCC ;  A0K484, MURD_BURCH ;
DR   Q0BIK3, MURD_BURCM ;  A9AJ18, MURD_BURM1 ;  A3MR61, MURD_BURM7 ;
DR   A2S5U7, MURD_BURM9 ;  Q62GS5, MURD_BURMA ;  A1V0S0, MURD_BURMS ;
DR   A3NZL7, MURD_BURP0 ;  Q3JND6, MURD_BURP1 ;  A3NDW6, MURD_BURP6 ;
DR   B2JHG2, MURD_BURP8 ;  B2SYX8, MURD_BURPP ;  Q63QJ5, MURD_BURPS ;
DR   Q39JX2, MURD_BURS3 ;  Q2SZI5, MURD_BURTA ;  A4JB92, MURD_BURVG ;
DR   Q13TZ0, MURD_BURXL ;  A4XI02, MURD_CALS8 ;  A8FKL9, MURD_CAMJ8 ;
DR   A7H4U5, MURD_CAMJD ;  Q9PI73, MURD_CAMJE ;  A1VYE9, MURD_CAMJJ ;
DR   Q5HW34, MURD_CAMJR ;  Q3AAE4, MURD_CARHZ ;  B8H096, MURD_CAUCN ;
DR   Q9A597, MURD_CAUCR ;  B0T833, MURD_CAUSK ;  Q5L521, MURD_CHLAB ;
DR   Q3ANV5, MURD_CHLCH ;  Q821S1, MURD_CHLCV ;  Q255W7, MURD_CHLFF ;
DR   B3EIL0, MURD_CHLL2 ;  Q9PLG5, MURD_CHLMU ;  B3QLW6, MURD_CHLP8 ;
DR   B3EQC0, MURD_CHLPB ;  A1BJY0, MURD_CHLPD ;  Q9Z705, MURD_CHLPN ;
DR   B0B8Y4, MURD_CHLT2 ;  B3QWT5, MURD_CHLT3 ;  Q3KKT4, MURD_CHLTA ;
DR   B0BAL3, MURD_CHLTB ;  Q8KGD2, MURD_CHLTE ;  O84763, MURD_CHLTR ;
DR   Q1QVG5, MURD_CHRSD ;  Q7NPZ7, MURD_CHRVO ;  Q97EB9, MURD_CLOAB ;
DR   A7FZA3, MURD_CLOB1 ;  C3KVT7, MURD_CLOB6 ;  A6LPL7, MURD_CLOB8 ;
DR   B2UXV7, MURD_CLOBA ;  B2TIC9, MURD_CLOBB ;  A5I7P2, MURD_CLOBH ;
DR   C1FNC3, MURD_CLOBJ ;  B1IGJ0, MURD_CLOBK ;  A7GJB0, MURD_CLOBL ;
DR   B1KTB9, MURD_CLOBM ;  B8I2T4, MURD_CLOCE ;  Q182Y7, MURD_CLOD6 ;
DR   B9DY75, MURD_CLOK1 ;  A5N4L3, MURD_CLOK5 ;  A0PXN6, MURD_CLONN ;
DR   Q0TMJ3, MURD_CLOP1 ;  Q8XHM4, MURD_CLOPE ;  A9KLU2, MURD_CLOPH ;
DR   Q0SQ91, MURD_CLOPS ;  Q899G5, MURD_CLOTE ;  A3DE94, MURD_CLOTH ;
DR   Q47VQ7, MURD_COLP3 ;  Q6NGC6, MURD_CORDI ;  Q8FNT8, MURD_COREF ;
DR   Q4JW97, MURD_CORJK ;  B1VHC6, MURD_CORU7 ;  B6J5K6, MURD_COXB1 ;
DR   B6J2Q5, MURD_COXB2 ;  A9KER6, MURD_COXBN ;  A9NA40, MURD_COXBR ;
DR   Q83F20, MURD_COXBU ;  Q46WZ2, MURD_CUPPJ ;  B1X090, MURD_CYAA5 ;
DR   B8HW13, MURD_CYAP4 ;  B7KH28, MURD_CYAP7 ;  B7K318, MURD_CYAP8 ;
DR   Q11RH3, MURD_CYTH3 ;  Q47AA2, MURD_DECAR ;  Q1J147, MURD_DEIGD ;
DR   Q9RRJ4, MURD_DEIRA ;  B8FBS0, MURD_DESAA ;  B8IZT9, MURD_DESDA ;
DR   Q313Q5, MURD_DESDG ;  B8FT58, MURD_DESHD ;  Q24TE4, MURD_DESHY ;
DR   A8ZXW5, MURD_DESOH ;  Q6AJ52, MURD_DESPS ;  A4J2A9, MURD_DESRM ;
DR   Q728U6, MURD_DESVH ;  B8DP81, MURD_DESVM ;  A1VBE6, MURD_DESVV ;
DR   A8LS92, MURD_DINSH ;  Q8X9Y9, MURD_ECO57 ;  Q0TLQ1, MURD_ECOL5 ;
DR   Q8FL65, MURD_ECOL6 ;  P14900, MURD_ECOLI ;  Q1RGA7, MURD_ECOUT ;
DR   B2KEW4, MURD_ELUMP ;  O07108, MURD_ENTFA ;  O07669, MURD_ENTHR ;
DR   Q6D0I1, MURD_ERWCT ;  C4Z534, MURD_EUBE2 ;  B1YIT8, MURD_EXIS2 ;
DR   A7HNT0, MURD_FERNB ;  B0TZ72, MURD_FRAP2 ;  Q2JD52, MURD_FRASC ;
DR   Q14J05, MURD_FRAT1 ;  A7NDX4, MURD_FRATF ;  Q2A1Z9, MURD_FRATH ;
DR   B2SDR8, MURD_FRATM ;  A0Q5C2, MURD_FRATN ;  Q0BKM8, MURD_FRATO ;
DR   Q5NHK3, MURD_FRATT ;  A4IZG9, MURD_FRATW ;  Q8RDQ1, MURD_FUSNN ;
DR   B5EBP9, MURD_GEOBB ;  Q5L0X7, MURD_GEOKA ;  B3E3Y4, MURD_GEOLS ;
DR   Q39YM1, MURD_GEOMG ;  B9M170, MURD_GEOSF ;  Q748D4, MURD_GEOSL ;
DR   C6DZK4, MURD_GEOSM ;  C5D8M2, MURD_GEOSW ;  A5G8K2, MURD_GEOUR ;
DR   Q7NEZ5, MURD_GLOVI ;  Q5FUJ7, MURD_GLUOX ;  A0M529, MURD_GRAFK ;
DR   Q7VP56, MURD_HAEDU ;  Q4QLG0, MURD_HAEI8 ;  A5UCX0, MURD_HAEIE ;
DR   A5UIR0, MURD_HAEIG ;  P45063, MURD_HAEIN ;  Q2S9Z0, MURD_HAHCH ;
DR   B5Z6L9, MURD_HELPG ;  Q1CU35, MURD_HELPH ;  Q9ZLY0, MURD_HELPJ ;
DR   O25236, MURD_HELPY ;  B4U609, MURD_HYDS0 ;  Q5R0M3, MURD_IDILO ;
DR   Q28NN2, MURD_JANSC ;  Q5FKV3, MURD_LACAC ;  Q039R8, MURD_LACC3 ;
DR   B3WDY1, MURD_LACCB ;  Q1GAT6, MURD_LACDA ;  Q04B73, MURD_LACDB ;
DR   B2GB77, MURD_LACF3 ;  Q042P8, MURD_LACGA ;  A8YUN8, MURD_LACH4 ;
DR   Q74JY5, MURD_LACJO ;  Q9CF91, MURD_LACLA ;  A2RJQ3, MURD_LACLM ;
DR   Q02XX9, MURD_LACLS ;  Q88V80, MURD_LACPL ;  A5VJ32, MURD_LACRD ;
DR   B2G6K4, MURD_LACRJ ;  Q1WT99, MURD_LACS1 ;  Q38XM9, MURD_LACSS ;
DR   Q1MPC1, MURD_LAWIP ;  Q5X1S4, MURD_LEGPA ;  Q5ZSA3, MURD_LEGPH ;
DR   Q5WTI5, MURD_LEGPL ;  Q6AE62, MURD_LEIXX ;  Q04UG6, MURD_LEPBJ ;
DR   Q04Z09, MURD_LEPBL ;  Q72NP4, MURD_LEPIC ;  Q8F7V4, MURD_LEPIN ;
DR   B1MXV9, MURD_LEUCK ;  Q03W34, MURD_LEUMM ;  Q929Y1, MURD_LISIN ;
DR   Q71XX7, MURD_LISMF ;  Q8Y5M1, MURD_LISMO ;  B9EB51, MURD_MACCJ ;
DR   Q2W0H5, MURD_MAGSA ;  Q65RY4, MURD_MANSM ;  A1U3G0, MURD_MARAV ;
DR   Q11GS3, MURD_MESSB ;  Q604V5, MURD_METCA ;  Q1GYZ9, MURD_METFK ;
DR   B0JRM9, MURD_MICAN ;  Q2RK81, MURD_MOOTA ;  A0QF50, MURD_MYCA1 ;
DR   Q7VEP7, MURD_MYCBO ;  A1KKJ8, MURD_MYCBP ;  C1AQ71, MURD_MYCBT ;
DR   B8ZQP8, MURD_MYCLB ;  P57995, MURD_MYCLE ;  Q73YQ6, MURD_MYCPA ;
DR   A0R018, MURD_MYCS2 ;  A5U4I2, MURD_MYCTA ;  O06222, MURD_MYCTU ;
DR   A1TAX0, MURD_MYCVP ;  Q1D0S8, MURD_MYXXD ;  B2A2H0, MURD_NATTJ ;
DR   Q5F6L6, MURD_NEIG1 ;  B4RQC7, MURD_NEIG2 ;  A9M2H5, MURD_NEIM0 ;
DR   Q9JSZ5, MURD_NEIMA ;  Q9K0Y4, MURD_NEIMB ;  A1KVL5, MURD_NEIMF ;
DR   Q0AJD9, MURD_NITEC ;  Q82VS5, MURD_NITEU ;  Q1QNU5, MURD_NITHX ;
DR   Q2Y636, MURD_NITMU ;  Q3J787, MURD_NITOC ;  Q3STT0, MURD_NITWN ;
DR   Q5YYY1, MURD_NOCFA ;  B2J6I3, MURD_NOSP7 ;  Q8YPS9, MURD_NOSS1 ;
DR   Q2G997, MURD_NOVAD ;  Q8ER50, MURD_OCEIH ;  Q04ES9, MURD_OENOB ;
DR   A1AZK7, MURD_PARDP ;  Q6MBS4, MURD_PARUW ;  Q9CPB0, MURD_PASMU ;
DR   Q03EY1, MURD_PEDPA ;  Q3A2G4, MURD_PELCD ;  Q3B127, MURD_PELLD ;
DR   B4SHE6, MURD_PELPB ;  A1AU63, MURD_PELPD ;  A5D147, MURD_PELTS ;
DR   A9BGS7, MURD_PETMO ;  B4RFS2, MURD_PHEZH ;  Q7N145, MURD_PHOLL ;
DR   Q6LMF4, MURD_PHOPR ;  Q12EL7, MURD_POLSJ ;  B2RIE9, MURD_PORG3 ;
DR   Q7MWM5, MURD_PORGI ;  Q6A9Q4, MURD_PROAC ;  A2BY75, MURD_PROM5 ;
DR   Q319C4, MURD_PROM9 ;  Q7VAM1, MURD_PROMA ;  Q7V5V5, MURD_PROMM ;
DR   Q7V0A5, MURD_PROMP ;  Q46JA8, MURD_PROMT ;  A4SH04, MURD_PROVI ;
DR   Q48EF6, MURD_PSE14 ;  Q9HVZ9, MURD_PSEAE ;  Q4K6J1, MURD_PSEF5 ;
DR   Q3IG02, MURD_PSEHT ;  Q3K742, MURD_PSEPF ;  Q88N78, MURD_PSEPK ;
DR   Q87WY3, MURD_PSESM ;  Q4ZNY8, MURD_PSEU2 ;  Q4FQ21, MURD_PSYA2 ;
DR   Q1Q883, MURD_PSYCK ;  Q1LIM4, MURD_RALME ;  Q8XVI5, MURD_RALSO ;
DR   Q2K6B9, MURD_RHIEC ;  Q1ME31, MURD_RHIL3 ;  Q98KB1, MURD_RHILO ;
DR   Q52953, MURD_RHIME ;  Q21SW7, MURD_RHOFD ;  Q2IYL0, MURD_RHOP2 ;
DR   Q6N409, MURD_RHOPA ;  Q216E0, MURD_RHOPB ;  Q2RVU2, MURD_RHORT ;
DR   A3PHS4, MURD_RHOS1 ;  Q3J4M6, MURD_RHOS4 ;  A4WQD2, MURD_RHOS5 ;
DR   B9KNJ5, MURD_RHOSK ;  Q0SHR9, MURD_RHOSR ;  Q1RI52, MURD_RICBR ;
DR   Q92I60, MURD_RICCN ;  Q4ULT8, MURD_RICFE ;  Q9ZDC2, MURD_RICPR ;
DR   Q68WW9, MURD_RICTY ;  A7NI97, MURD_ROSCS ;  Q163I6, MURD_ROSDO ;
DR   A5UZT4, MURD_ROSS1 ;  Q1AVX1, MURD_RUBXD ;  Q21MH1, MURD_SACD2 ;
DR   Q57TD2, MURD_SALCH ;  Q5PDC2, MURD_SALPA ;  Q2S530, MURD_SALRD ;
DR   Q8Z9H0, MURD_SALTI ;  Q8ZRU4, MURD_SALTY ;  Q8E9P6, MURD_SHEON ;
DR   Q9F1N2, MURD_SHEVD ;  Q326E7, MURD_SHIBS ;  Q32K04, MURD_SHIDS ;
DR   Q83MF9, MURD_SHIFL ;  Q3Z5S1, MURD_SHISS ;  Q5LU71, MURD_SILPO ;
DR   Q1GIV4, MURD_SILST ;  Q2NVV3, MURD_SODGM ;  Q01Q46, MURD_SOLUE ;
DR   Q1GRX7, MURD_SPHAL ;  A7X1C4, MURD_STAA1 ;  A6U103, MURD_STAA2 ;
DR   Q2FHQ4, MURD_STAA3 ;  Q2FZ92, MURD_STAA8 ;  A5IS69, MURD_STAA9 ;
DR   Q2YXD9, MURD_STAAB ;  Q5HGP8, MURD_STAAC ;  A6QG83, MURD_STAAE ;
DR   P0A089, MURD_STAAM ;  P0A090, MURD_STAAN ;  Q6GHQ2, MURD_STAAR ;
DR   Q6GA29, MURD_STAAS ;  A8Z3M4, MURD_STAAT ;  P0A091, MURD_STAAU ;
DR   Q8NX35, MURD_STAAW ;  B9DPR3, MURD_STACT ;  Q5HQ09, MURD_STAEQ ;
DR   Q8CSX6, MURD_STAES ;  Q4L5N4, MURD_STAHJ ;  Q49WW5, MURD_STAS1 ;
DR   Q3K2P4, MURD_STRA1 ;  Q8E6P1, MURD_STRA3 ;  Q8E186, MURD_STRA5 ;
DR   Q82AD8, MURD_STRAW ;  Q9S2W9, MURD_STRCO ;  B4U1U3, MURD_STREM ;
DR   A8AW14, MURD_STRGC ;  Q8DVE3, MURD_STRMU ;  P0C0D8, MURD_STRP1 ;
DR   Q04LK1, MURD_STRP2 ;  P0DC52, MURD_STRP3 ;  B5E2Z8, MURD_STRP4 ;
DR   Q5XB04, MURD_STRP6 ;  C1C648, MURD_STRP7 ;  Q8P063, MURD_STRP8 ;
DR   Q1JAT4, MURD_STRPB ;  Q1JKY4, MURD_STRPC ;  Q1JG10, MURD_STRPD ;
DR   Q1J5S5, MURD_STRPF ;  A2RDK9, MURD_STRPG ;  B1IAM3, MURD_STRPI ;
DR   B8ZMZ6, MURD_STRPJ ;  Q48SK8, MURD_STRPM ;  Q97RU8, MURD_STRPN ;
DR   P0DC53, MURD_STRPQ ;  B2IN76, MURD_STRPS ;  P0C0D7, MURD_STRPY ;
DR   B5XMA3, MURD_STRPZ ;  Q8DQM2, MURD_STRR6 ;  A4VZT8, MURD_STRS2 ;
DR   A3CLN5, MURD_STRSV ;  A4VTK3, MURD_STRSY ;  Q5M0D5, MURD_STRT1 ;
DR   Q5M4Y2, MURD_STRT2 ;  Q03L98, MURD_STRTD ;  B9DUV7, MURD_STRU0 ;
DR   C1CD51, MURD_STRZJ ;  C1CJF2, MURD_STRZP ;  C1CQG4, MURD_STRZT ;
DR   Q67QM7, MURD_SYMTH ;  Q2LR50, MURD_SYNAS ;  Q31MM2, MURD_SYNE7 ;
DR   Q2JVR9, MURD_SYNJA ;  Q2JHP5, MURD_SYNJB ;  Q5MZA8, MURD_SYNP6 ;
DR   Q7U8T1, MURD_SYNPX ;  Q3AZI5, MURD_SYNS9 ;  Q3AHP0, MURD_SYNSC ;
DR   P73668, MURD_SYNY3 ;  C5BP36, MURD_TERTT ;  B7IFU5, MURD_THEAB ;
DR   Q8DMN8, MURD_THEEB ;  Q47QX1, MURD_THEFY ;  A8F4W9, MURD_THELT ;
DR   A6LJK7, MURD_THEM4 ;  Q9WY76, MURD_THEMA ;  B9K6P5, MURD_THENN ;
DR   A5IKI7, MURD_THEP1 ;  B0K8K5, MURD_THEP3 ;  B0K3H2, MURD_THEPX ;
DR   B1L9R9, MURD_THESQ ;  Q72JQ1, MURD_THET2 ;  Q5SJD2, MURD_THET8 ;
DR   Q8R9G4, MURD_THETN ;  Q31I61, MURD_THICR ;  Q3SMH5, MURD_THIDA ;
DR   O83873, MURD_TREPA ;  Q10WA5, MURD_TRIEI ;  Q83HK0, MURD_TROW8 ;
DR   Q83GN2, MURD_TROWT ;  A5F5N1, MURD_VIBC3 ;  Q9KPG5, MURD_VIBCH ;
DR   Q5E2P8, MURD_VIBF1 ;  B5FB37, MURD_VIBFM ;  A7MXR3, MURD_VIBHB ;
DR   Q87SG6, MURD_VIBPA ;  B7VJ01, MURD_VIBSL ;  Q8DEK8, MURD_VIBVU ;
DR   Q7MNV3, MURD_VIBVY ;  Q8D2Z4, MURD_WIGBR ;  Q73GT3, MURD_WOLPM ;
DR   Q5GSC8, MURD_WOLTR ;  Q8PII9, MURD_XANAC ;  Q3BR29, MURD_XANC5 ;
DR   Q4UWX9, MURD_XANC8 ;  Q8P775, MURD_XANCP ;  Q2P5V2, MURD_XANOM ;
DR   Q5H2Y1, MURD_XANOR ;  Q9PEB0, MURD_XYLFA ;  Q87EA7, MURD_XYLFT ;
DR   Q1C212, MURD_YERPA ;  Q8ZIF1, MURD_YERPE ;  Q1CMM9, MURD_YERPN ;
DR   Q66EK7, MURD_YERPS ;  Q5NPA7, MURD_ZYMMO ;
//
ID   6.3.2.10
DE   UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.
AN   MurF synthetase.
AN   UDP-MurNAc-L-Ala-D-Glu-L-Lys:D-Ala-D-Ala ligase.
AN   UDP-MurNAc-pentapeptide synthetase.
AN   UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine
AN   synthetase.
AN   UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-
AN   alanyl-D-alanine synthetase.
AN   UDP-N-acetylmuramoylalanine-D-glutamyl-lysine--D-alanyl-D-alanine ligase.
AN   UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-
AN   alanine ligase.
AN   UDP-N-acetylmuramoylalanyl-D-glutamyl-lysine-D-alanyl-D-alanine ligase.
AN   UDPacetylmuramoylpentapeptide synthetase.
AN   Uridine diphosphoacetylmuramoylpentapeptide synthetase.
CA   ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + D-alanyl-
CA   D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-
CA   glutamyl-L-lysyl-D-alanyl-D-alanine.
CC   -!- Involved with EC 6.3.2.4, EC 6.3.2.7 or EC 6.3.2.13, EC 6.3.2.8 and
CC       EC 6.3.2.9 in the synthesis of a cell-wall peptide.
CC   -!- Also catalyzes the reaction when the C-terminal residue of the
CC       tripeptide is meso-2,4-diaminoheptanedioate (acylated at its
CC       L-center), linking the D-Ala--D-Ala to the carboxy group of the
CC       L-center.
CC   -!- Formerly EC 6.3.2.15.
DR   P96613, MURF_BACSU ;  Q44777, MURF_BORBU ;  P57315, MURF_BUCAI ;
DR   Q89AQ1, MURF_BUCBP ;  P11880, MURF_ECOLI ;  P45061, MURF_HAEIN ;
DR   P0A5L5, MURF_MYCBO ;  O69556, MURF_MYCLE ;  P0A5L4, MURF_MYCTU ;
DR   Q92H60, MURF_RICCN ;  Q9AKP1, MURF_RICMO ;  O05953, MURF_RICPR ;
DR   O33804, MURF_STRTO ;  P45450, MURF_SYNY3 ;  O83401, MURF_TREPA ;
//
ID   6.3.2.11
DE   Carnosine synthase.
AN   Carnosine synthetase.
CA   ATP + L-histidine + beta-alanine = ADP + phosphate + carnosine.
CC   -!- This enzyme was thought to form AMP, but studies with highly purified
CC       enzyme proved that it forms ADP.
CC   -!- Carnosine is a dipeptide that is present at high concentrations in
CC       skeletal muscle and the olfactory bulb of vertebrates.
CC   -!- It is also found in the skeletal muscle of some invertebrates.
CC   -!- The enzyme can also catalyze the formation of homocarnosine from
CC       4-aminobutyrate and L-histidine, with much lower activity.
DR   D3KCC4, CRNS1_CHICK;  A5YM72, CRNS1_HUMAN;  Q6ZPS2, CRNS1_MOUSE;
//
ID   6.3.2.12
DE   Dihydrofolate synthase.
AN   7,8-dihydrofolate synthetase.
AN   7,8-dihydropteroate:L-glutamate ligase (ADP).
AN   DHFS.
AN   Dihydrofolate synthetase.
AN   Dihydrofolate synthetase-folylpolyglutamate synthetase.
AN   Dihydropteroate:L-glutamate ligase (ADP-forming).
AN   FHFS.
AN   FHFS/FPGS.
AN   Folylpoly-(gamma-glutamate) synthetase-dihydrofolate synthase.
AN   H(2)-folate synthetase.
CA   ATP + 7,8-dihydropteroate + L-glutamate = ADP + phosphate + 7,8-
CA   dihydropteroylglutamate.
CC   -!- In some bacteria, a single protein catalyzes both this activity and
CC       that of EC 6.3.2.17, the combined activity of which leads to the
CC       formation of the coenzyme polyglutamated tetrahydropteroate
CC       (H(4)PteGlu(n)), i.e. various tetrahydrofolates.
CC   -!- In contrast, the activities are located on separate proteins in most
CC       eukaryotes studied to date.
CC   -!- This enzyme is reponsible for attaching the first glutamate residue
CC       to dihydropteroate to form dihydrofolate and is present only in those
CC       organisms that have the ability to synthesize tetrahydrofolate de
CC       novo, e.g. plants, most bacteria, fungi and protozoa.
DR   P57265, FOLC_BUCAI ;  Q8K9X3, FOLC_BUCAP ;  Q89AT2, FOLC_BUCBP ;
DR   P08192, FOLC_ECOLI ;
//
ID   6.3.2.13
DE   UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase.
AN   MurE synthetase.
AN   UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diamino-heptanedioate
AN   ligase (ADP-forming).
AN   UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate
AN   synthetase.
AN   UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase.
AN   UDP-N-acetylmuramyl-tripeptide synthetase.
CA   ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + meso-2,6-
CA   diaminoheptanedioate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-
CA   gamma-glutamyl-meso-2,6-diamino-heptanedioate.
CC   -!- Involved with EC 6.3.2.4, EC 6.3.2.8, EC 6.3.2.9 and EC 6.3.2.10 in
CC       the synthesis of a cell-wall peptide.
CC   -!- This enzyme adds diaminopimelate in Gram-negative organisms and in
CC       some Gram-positive organisms; in others EC 6.3.2.7 adds lysine
CC       instead.
CC   -!- It is the amino group of the L-center of the diaminopimelate that is
CC       acylated.
DR   Q97H84, MURE1_CLOAB;  Q8CZE6, MURE1_OCEIH;  Q97FC1, MURE2_CLOAB;
DR   A1WC11, MURE_ACISJ ;  A3MY85, MURE_ACTP2 ;  Q8UDM3, MURE_AGRT5 ;
DR   Q0VS07, MURE_ALCBS ;  Q0A6J7, MURE_ALHEH ;  A6TS66, MURE_ALKMQ ;
DR   A8MH31, MURE_ALKOO ;  Q5PBF1, MURE_ANAMM ;  Q3ME15, MURE_ANAVT ;
DR   O67631, MURE_AQUAE ;  A7Z4E1, MURE_BACA2 ;  Q81WC7, MURE_BACAN ;
DR   Q819Q0, MURE_BACCR ;  Q5LIJ3, MURE_BACFN ;  Q64ZL7, MURE_BACFR ;
DR   Q9K9S4, MURE_BACHD ;  Q65JY4, MURE_BACLD ;  Q03523, MURE_BACSU ;
DR   Q8A254, MURE_BACTN ;  A6L075, MURE_BACV8 ;  Q7VQJ2, MURE_BLOFL ;
DR   Q89FU2, MURE_BRAJA ;  Q8YI71, MURE_BRUME ;  Q8FZP0, MURE_BRUSU ;
DR   P57316, MURE_BUCAI ;  O85298, MURE_BUCAP ;  P59419, MURE_BUCBP ;
DR   O69290, MURE_CAMJE ;  Q9A595, MURE_CAUCR ;  Q5L6B2, MURE_CHLAB ;
DR   Q823N2, MURE_CHLCV ;  Q253Y4, MURE_CHLFF ;  Q9PKC6, MURE_CHLMU ;
DR   A1BJY3, MURE_CHLPD ;  Q9Z8C5, MURE_CHLPN ;  Q3KM93, MURE_CHLTA ;
DR   Q8KGC9, MURE_CHLTE ;  O84271, MURE_CHLTR ;  Q7NPZ4, MURE_CHRVO ;
DR   A7FTY1, MURE_CLOB1 ;  A5I1T6, MURE_CLOBH ;  Q182Z8, MURE_CLOD6 ;
DR   Q8XJ99, MURE_CLOPE ;  Q894B7, MURE_CLOTE ;  Q8FNT5, MURE_COREF ;
DR   Q8NNN0, MURE_CORGL ;  Q83F28, MURE_COXBU ;  Q11RG9, MURE_CYTH3 ;
DR   Q8X9Z2, MURE_ECO57 ;  Q8FL67, MURE_ECOL6 ;  P22188, MURE_ECOLI ;
DR   A4W6I8, MURE_ENT38 ;  Q6D0H8, MURE_ERWCT ;  Q8R635, MURE_FUSNN ;
DR   Q5L0Y0, MURE_GEOKA ;  Q39YM4, MURE_GEOMG ;  Q748D2, MURE_GEOSL ;
DR   A4IM04, MURE_GEOTN ;  Q7NFN2, MURE_GLOVI ;  Q7VP59, MURE_HAEDU ;
DR   Q4QLG3, MURE_HAEI8 ;  A5UCX3, MURE_HAEIE ;  A5UIQ7, MURE_HAEIG ;
DR   P45060, MURE_HAEIN ;  Q0I1D8, MURE_HAES1 ;  Q7VF14, MURE_HELHP ;
DR   Q9ZJC6, MURE_HELPJ ;  O26027, MURE_HELPY ;  A6T2G3, MURE_JANMA ;
DR   Q88Y23, MURE_LACPL ;  Q1MPC4, MURE_LAWIP ;  Q04V91, MURE_LEPBJ ;
DR   Q04Y85, MURE_LEPBL ;  Q72R81, MURE_LEPIC ;  Q8F4J4, MURE_LEPIN ;
DR   Q929X9, MURE_LISIN ;  Q71XX5, MURE_LISMF ;  Q8Y5L9, MURE_LISMO ;
DR   Q11GS0, MURE_MESSB ;  A0QF47, MURE_MYCA1 ;  P65478, MURE_MYCBO ;
DR   O69557, MURE_MYCLE ;  Q73YQ3, MURE_MYCPA ;  P65477, MURE_MYCTU ;
DR   Q9JSZ0, MURE_NEIMA ;  Q9K0Y9, MURE_NEIMB ;  Q82VS8, MURE_NITEU ;
DR   Q8YWF0, MURE_NOSS1 ;  A6LEU7, MURE_PARD8 ;  P57815, MURE_PASMU ;
DR   Q7N142, MURE_PHOLL ;  Q7MWM7, MURE_PORGI ;  A2C0L8, MURE_PROM1 ;
DR   Q7VDG4, MURE_PROMA ;  Q7V8U6, MURE_PROMM ;  Q7V2Q8, MURE_PROMP ;
DR   Q46LZ6, MURE_PROMT ;  Q59650, MURE_PSEAE ;  A4XQR9, MURE_PSEMY ;
DR   Q88N81, MURE_PSEPK ;  Q87WY0, MURE_PSESM ;  Q8XVI2, MURE_RALSO ;
DR   Q98KA8, MURE_RHILO ;  Q92NL6, MURE_RHIME ;  Q1RI81, MURE_RICBR ;
DR   Q92H59, MURE_RICCN ;  Q4UMI9, MURE_RICFE ;  Q9AKP0, MURE_RICMO ;
DR   O05954, MURE_RICPR ;  Q9AKI7, MURE_RICRI ;  Q68WE2, MURE_RICTY ;
DR   Q57TD5, MURE_SALCH ;  Q5PDH1, MURE_SALPA ;  Q8Z9H3, MURE_SALTI ;
DR   Q8ZRU7, MURE_SALTY ;  Q83MG0, MURE_SHIFL ;  Q2NVV6, MURE_SODGM ;
DR   Q01Q43, MURE_SOLUE ;  Q82AE1, MURE_STRAW ;  Q9S2W7, MURE_STRCO ;
DR   Q31N55, MURE_SYNE7 ;  A5GJA5, MURE_SYNPW ;  Q7U5L3, MURE_SYNPX ;
DR   Q0ICH2, MURE_SYNS3 ;  Q0AYR3, MURE_SYNWW ;  Q55469, MURE_SYNY3 ;
DR   Q8DJI4, MURE_THEEB ;  Q8R9G2, MURE_THETN ;  Q9X6N4, MURE_VIBCH ;
DR   Q87SG9, MURE_VIBPA ;  Q8DEK5, MURE_VIBVU ;  Q7MNV6, MURE_VIBVY ;
DR   Q8D2Z1, MURE_WIGBR ;  Q7M8F9, MURE_WOLSU ;  Q8PPB2, MURE_XANAC ;
DR   Q4UQW6, MURE_XANC8 ;  Q8PCK4, MURE_XANCP ;  Q2NZB4, MURE_XANOM ;
DR   Q5GW37, MURE_XANOR ;  Q9PF85, MURE_XYLFA ;  Q87AF5, MURE_XYLFT ;
DR   Q8ZIF4, MURE_YERPE ;  Q9RNM2, MURE_ZYMMO ;
//
ID   6.3.2.14
DE   2,3-dihydroxybenzoate--serine ligase.
AN   N-(2,3-dihydroxybenzoyl)-serine synthetase.
CA   ATP + 2,3-dihydroxybenzoate + L-serine = products of ATP breakdown +
CA   N-(2,3-dihydroxybenzoyl)-L-serine.
//
ID   6.3.2.15
DE   Transferred entry: 6.3.2.10.
//
ID   6.3.2.16
DE   D-alanine--alanyl-poly(glycerolphosphate) ligase.
AN   D-alanine:membrane-acceptor ligase.
AN   D-alanyl-alanyl-poly(glycerolphosphate) synthetase.
CA   ATP + D-alanine + alanyl-poly(glycerolphosphate) = ADP + phosphate +
CA   D-alanyl-alanyl-poly(glycerolphosphate).
CC   -!- Involved in the synthesis of teichoic acids.
//
ID   6.3.2.17
DE   Tetrahydrofolate synthase.
AN   Folate polyglutamate synthetase.
AN   Folylpoly(gamma-glutamate) synthase.
AN   Folylpoly-gamma-glutamate synthase.
AN   Folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase.
AN   Folylpolyglutamate synthase.
AN   Folylpolyglutamate synthetase.
AN   Folylpolyglutamyl synthetase.
AN   Formyltetrahydropteroyldiglutamate synthetase.
AN   FPGS.
AN   N(10)-formyltetrahydropteroyldiglutamate synthetase.
AN   Tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming).
AN   Tetrahydrofolylpolyglutamate synthase.
CA   ATP + tetrahydropteroyl-(gamma-Glu)(n) + L-glutamate = ADP + phosphate +
CA   tetrahydropteroyl-(gamma-Glu)(n+1).
CC   -!- In some bacteria, a single protein catalyzes both this activity and
CC       that of EC 6.3.2.12, the combined activity of which leads to the
CC       formation of the coenzyme polyglutamated tetrahydropteroate
CC       (H(4)PteGlu(n)), i.e. various tetrahydrofolates (H(4)folate).
CC   -!- In contrast, the activities are located on separate proteins in most
CC       eukaryotes studied to date.
CC   -!- In Arabidopsis thaliana, this enzyme is present as distinct isoforms
CC       in the mitochondria, the cytosol and the chloroplast.
CC   -!- Each isoform is encoded by a separate gene, a situation that is
CC       unique among eukaryotes.
CC   -!- As the affinity of folate-dependent enzymes increases markedly with
CC       the number of glutamic residues, the tetrahydropteroyl polyglutamates
CC       are the preferred coenzymes of C(1) metabolism.
CC   -!- The enzymes from different sources (particularly eukaryotes versus
CC       prokaryotes) have different substrate specificities with regard to
CC       one-carbon substituents and the number of glutamate residues present
CC       on the tetrahydrofolates.
PR   PROSITE; PDOC00773;
DR   Q05865, FOLC_BACSU ;  A6H751, FOLC_BOVIN ;  P57265, FOLC_BUCAI ;
DR   Q8K9X3, FOLC_BUCAP ;  Q89AT2, FOLC_BUCBP ;  Q09509, FOLC_CAEEL ;
DR   Q924L9, FOLC_CRIGR ;  Q54CY5, FOLC_DICDI ;  P08192, FOLC_ECOLI ;
DR   P43775, FOLC_HAEIN ;  Q05932, FOLC_HUMAN ;  P15925, FOLC_LACCA ;
DR   P48760, FOLC_MOUSE ;  P36001, FOLC_YEAST ;  Q9UTD0, FOLD_SCHPO ;
DR   Q12676, FOLD_YEAST ;  Q9Y893, FOLE_CANAL ;  O13492, FOLE_NEUCR ;
DR   O74742, FOLE_SCHPO ;  Q08645, FOLE_YEAST ;  P13337, VG29_BPT4  ;
//
ID   6.3.2.18
DE   Gamma-glutamylhistamine synthase.
AN   Gamma-GHA synthetase.
CA   ATP + L-glutamate + histamine = products of ATP breakdown + N(alpha)-
CA   gamma-L-glutamylhistamine.
//
ID   6.3.2.19
DE   Ubiquitin--protein ligase.
AN   Ubiquitin-activating enzyme.
AN   Ubiquitin-conjugating enzyme.
CA   ATP + ubiquitin + protein lysine = AMP + diphosphate + protein
CA   N-ubiquityllysine.
CC   -!- Ubiquitin is coupled to protein by a peptide bond between the
CC       C-terminal glycine of ubiquitin and epsilon-amino groups of lysine
CC       residues in the protein.
CC   -!- An intermediate in the reaction contains one ubiquitin residue bound
CC       as a thioester to the enzyme, and a residue of ubiquitin adenylate
CC       non-covalently bound to the enzyme.
PR   PROSITE; PDOC00163;
DR   Q8LGF7, PEX4_ARATH ;  Q14258, TRI25_HUMAN;  Q61510, TRI25_MOUSE;
DR   Q6ZWY6, U2D2B_MOUSE;  P70711, U2D2B_RAT  ;  Q9VM35, U2QL1_DROME;
DR   A1L167, U2QL1_HUMAN;  A0PJN4, U2QL1_MOUSE;  Q2TA10, UB2D1_BOVIN;
DR   P51668, UB2D1_HUMAN;  P61080, UB2D1_MOUSE;  D3ZDK2, UB2D1_RAT  ;
DR   Q1RMX2, UB2D2_BOVIN;  P62837, UB2D2_HUMAN;  P62838, UB2D2_MOUSE;
DR   Q06AA9, UB2D2_PIG  ;  P62839, UB2D2_RAT  ;  P62840, UB2D2_XENLA;
DR   Q3ZCF7, UB2D3_BOVIN;  P61077, UB2D3_HUMAN;  Q4R5N4, UB2D3_MACFA;
DR   P61079, UB2D3_MOUSE;  Q5R4V7, UB2D3_PONAB;  P61078, UB2D3_RAT  ;
DR   Q9Y2X8, UB2D4_HUMAN;  A5PKP9, UB2D4_XENLA;  P51965, UB2E1_HUMAN;
DR   P52482, UB2E1_MOUSE;  Q96LR5, UB2E2_HUMAN;  Q91W82, UB2E2_MOUSE;
DR   Q2T9X7, UB2E3_BOVIN;  Q969T4, UB2E3_HUMAN;  P52483, UB2E3_MOUSE;
DR   P62253, UB2G1_HUMAN;  Q4R5Y8, UB2G1_MACFA;  P62254, UB2G1_MOUSE;
DR   P62255, UB2G1_RAT  ;  Q17QG5, UB2G2_BOVIN;  P60604, UB2G2_HUMAN;
DR   P60605, UB2G2_MOUSE;  Q5RF84, UB2G2_PONAB;  Q9Y385, UB2J1_HUMAN;
DR   Q9JJZ4, UB2J1_MOUSE;  Q2TA03, UB2J2_BOVIN;  Q54LP7, UB2J2_DICDI;
DR   Q8N2K1, UB2J2_HUMAN;  Q6P073, UB2J2_MOUSE;  Q54AK6, UB2JL_DICDI;
DR   Q3MHP1, UB2L3_BOVIN;  P68036, UB2L3_HUMAN;  P68037, UB2L3_MOUSE;
DR   Q5R5I4, UB2L3_PONAB;  A5PJC4, UB2L6_BOVIN;  O14933, UB2L6_HUMAN;
DR   Q9QZU9, UB2L6_MOUSE;  Q4V8J2, UB2L6_RAT  ;  Q7Z7E8, UB2Q1_HUMAN;
DR   Q7TSS2, UB2Q1_MOUSE;  Q32L27, UB2Q2_BOVIN;  Q8WVN8, UB2Q2_HUMAN;
DR   Q8K2Z8, UB2Q2_MOUSE;  Q7YQJ9, UB2Q2_RABIT;  P49427, UB2R1_HUMAN;
DR   Q8CFI2, UB2R1_MOUSE;  Q712K3, UB2R2_HUMAN;  Q6ZWZ2, UB2R2_MOUSE;
DR   Q29503, UB2R2_RABIT;  A1L3K1, UB2SA_XENLA;  Q8AVU2, UB2SB_XENLA;
DR   Q76EZ2, UB2SC_XENLA;  P35133, UBC10_ARATH;  P35134, UBC11_ARATH;
DR   O00103, UBC11_SCHPO;  P52492, UBC11_YEAST;  Q9C9Y7, UBC12_ARATH;
DR   Q42541, UBC13_ARATH;  O13685, UBC13_SCHPO;  P52490, UBC13_YEAST;
DR   P42747, UBC14_ARATH;  Q9UTN8, UBC14_SCHPO;  P42743, UBC15_ARATH;
DR   Q9Y818, UBC15_SCHPO;  Q9FWT2, UBC16_ARATH;  Q9P6I1, UBC16_SCHPO;
DR   O23239, UBC17_ARATH;  Q9FMM0, UBC18_ARATH;  Q9LJZ5, UBC19_ARATH;
DR   P25865, UBC1_ARATH ;  P52478, UBC1_CAEEL ;  O74196, UBC1_COLGL ;
DR   Q9UVR2, UBC1_MAGO7 ;  Q5UQC9, UBC1_MIMIV ;  O74810, UBC1_SCHPO ;
DR   P21734, UBC1_YEAST ;  Q8L7T3, UBC20_ARATH;  P52484, UBC21_CAEEL;
DR   Q9FF66, UBC22_ARATH;  Q9ZVX1, UBC23_ARATH;  Q8VY10, UBC24_ARATH;
DR   Q9LUQ5, UBC25_ARATH;  Q8GY87, UBC26_ARATH;  Q9FI61, UBC27_ARATH;
DR   Q94F47, UBC28_ARATH;  Q9SLE4, UBC29_ARATH;  P42745, UBC2_ARATH ;
DR   Q75EB8, UBC2_ASHGO ;  Q4WLA7, UBC2_ASPFU ;  P35129, UBC2_CAEEL ;
DR   O74201, UBC2_CANAL ;  Q6FR76, UBC2_CANGA ;  P0CS17, UBC2_CRYNB ;
DR   P0CS16, UBC2_CRYNJ ;  Q6BU36, UBC2_DEBHA ;  Q553F3, UBC2_DICDI ;
DR   Q96UP5, UBC2_EMENI ;  Q6CUD9, UBC2_KLULA ;  P35130, UBC2_MEDSA ;
DR   Q5UQ57, UBC2_MIMIV ;  P78717, UBC2_NECHA ;  P52493, UBC2_NEUCR ;
DR   P23566, UBC2_SCHPO ;  Q58FS2, UBC2_TRIHA ;  Q4PFA5, UBC2_USTMA ;
DR   P25866, UBC2_WHEAT ;  Q6C093, UBC2_YARLI ;  P06104, UBC2_YEAST ;
DR   Q9FKT3, UBC30_ARATH;  Q9C8X7, UBC31_ARATH;  Q9LSP7, UBC32_ARATH;
DR   Q9FK29, UBC33_ARATH;  Q9SHI7, UBC34_ARATH;  Q94A97, UBC35_ARATH;
DR   Q9FZ48, UBC36_ARATH;  Q941B6, UBC37_ARATH;  P42746, UBC3_ARATH ;
DR   Q5UQ88, UBC3_MIMIV ;  P14682, UBC3_YEAST ;  P42748, UBC4_ARATH ;
DR   P43102, UBC4_CANAL ;  Q5UQ40, UBC4_MIMIV ;  P46595, UBC4_SCHPO ;
DR   P35135, UBC4_SOLLC ;  P16577, UBC4_WHEAT ;  P15731, UBC4_YEAST ;
DR   Q8S920, UBC5A_ORYSJ;  Q8S919, UBC5B_ORYSJ;  P42749, UBC5_ARATH ;
DR   P15732, UBC5_YEAST ;  P42750, UBC6_ARATH ;  Q74Z34, UBC6_ASHGO ;
DR   Q6FQK7, UBC6_CANGA ;  Q6BYG4, UBC6_DEBHA ;  Q6CMG6, UBC6_KLULA ;
DR   O42646, UBC6_SCHPO ;  P33296, UBC6_YEAST ;  Q42540, UBC7_ARATH ;
DR   P34477, UBC7_CAEEL ;  O00102, UBC7_SCHPO ;  P25868, UBC7_WHEAT ;
DR   Q02159, UBC7_YEAST ;  P52487, UBC84_DROME;  P35131, UBC8_ARATH ;
DR   Q9P7R4, UBC8_SCHPO ;  P28263, UBC8_YEAST ;  Q94490, UBCB_DICDI ;
DR   P25867, UBCD1_DROME;  P52485, UBCD2_DROME;  P52486, UBCD4_DROME;
DR   P25153, UBCD6_DROME;  Q86IZ3, UBCX_DICDI ;  O60015, UBCX_PICAN ;
DR   P49428, UBCX_PICPA ;  P29340, UBCX_YEAST ;  P27949, UBC_ASFB7  ;
DR   P0C8G3, UBC_ASFK5  ;  P25869, UBC_ASFM2  ;  P0C8G4, UBC_ASFP4  ;
DR   P0C8G5, UBC_ASFWA  ;  P49459, UBE2A_HUMAN;  Q9Z255, UBE2A_MOUSE;
DR   Q32P99, UBE2B_BOVIN;  P63146, UBE2B_HUMAN;  P63147, UBE2B_MOUSE;
DR   P63148, UBE2B_RABIT;  P63149, UBE2B_RAT  ;  Q32PA5, UBE2C_BOVIN;
DR   Q54XS6, UBE2C_DICDI;  Q9VTY6, UBE2C_DROME;  O00762, UBE2C_HUMAN;
DR   Q4R9D1, UBE2C_MACFA;  Q9D1C1, UBE2C_MOUSE;  Q95044, UBE2C_SPISO;
DR   P56616, UBE2C_XENLA;  Q32LN1, UBE2H_BOVIN;  P62256, UBE2H_HUMAN;
DR   P62257, UBE2H_MOUSE;  P61085, UBE2K_BOVIN;  P61086, UBE2K_HUMAN;
DR   P61087, UBE2K_MOUSE;  Q0P5K3, UBE2N_BOVIN;  Q86K32, UBE2N_DICDI;
DR   P35128, UBE2N_DROME;  P61088, UBE2N_HUMAN;  Q4R4I1, UBE2N_MACFA;
DR   P61089, UBE2N_MOUSE;  Q5R7J6, UBE2N_PONAB;  Q9EQX9, UBE2N_RAT  ;
DR   Q9C0C9, UBE2O_HUMAN;  Q6ZPJ3, UBE2O_MOUSE;  Q1RML1, UBE2S_BOVIN;
DR   C3Z724, UBE2S_BRAFL;  Q4V908, UBE2S_DANRE;  Q54I43, UBE2S_DICDI;
DR   B3MQV3, UBE2S_DROAN;  B3NWW9, UBE2S_DROER;  B4JKB7, UBE2S_DROGR;
DR   Q9VX25, UBE2S_DROME;  B4L7V4, UBE2S_DROMO;  B4H9W2, UBE2S_DROPE;
DR   B5DKM4, UBE2S_DROPS;  B4IF39, UBE2S_DROSE;  B4R6G1, UBE2S_DROSI;
DR   B4MA02, UBE2S_DROVI;  B4N208, UBE2S_DROWI;  B4Q2J2, UBE2S_DROYA;
DR   Q16763, UBE2S_HUMAN;  Q921J4, UBE2S_MOUSE;  A7SE05, UBE2S_NEMVE;
DR   C1C3R6, UBE2S_RANCA;  B5DFI8, UBE2S_RAT  ;  Q28F89, UBE2S_XENTR;
DR   Q32LD2, UBE2T_BOVIN;  Q9NPD8, UBE2T_HUMAN;  Q9CQ37, UBE2T_MOUSE;
DR   Q7ZY08, UBE2T_XENLA;  Q5VVX9, UBE2U_HUMAN;  Q95LM1, UBE2U_MACFA;
DR   Q4VBH4, UBE2W_DANRE;  Q55EY8, UBE2W_DICDI;  Q96B02, UBE2W_HUMAN;
DR   Q8VDW4, UBE2W_MOUSE;  Q6DG60, UBE2Z_DANRE;  Q9H832, UBE2Z_HUMAN;
DR   Q3UE37, UBE2Z_MOUSE;  Q3B7D1, UBE2Z_RAT  ;  Q6PCF7, UBE2Z_XENLA;
DR   Q66KB0, UBE2Z_XENTR;  Q8SSK3, Y1A1_ENCCU ;
//
ID   6.3.2.20
DE   Indoleacetate--lysine synthetase.
AN   IAA-lysine synthetase.
AN   N-(indole-3-acetyl)-L-lysine synthetase.
CA   ATP + (indol-3-yl)acetate + L-lysine = ADP + phosphate + N(6)-((indol-3-
CA   yl)acetyl)-L-lysine.
PR   PROSITE; PDOC00427;
DR   P18204, IAAL_PSESS ;
//
ID   6.3.2.21
DE   Ubiquitin--calmodulin ligase.
AN   Ubiquityl-calmodulin synthase.
AN   Ubiquityl-calmodulin synthetase.
CA   n ATP + calmodulin + n ubiquitin = n AMP + n diphosphate +
CA   (ubiquitin)(n)-calmodulin.
CC   -!- Specific for Ca(2+)-calmodulin from vertebrates.
CC   -!- At least 3 ubiquitin molecules can be coupled to lysine residues in
CC       calmodulin.
//
ID   6.3.2.22
DE   Transferred entry: 6.3.1.14.
//
ID   6.3.2.23
DE   Homoglutathione synthase.
AN   Beta-alanine specific hGSH synthetase.
AN   Homoglutathione synthetase.
CA   ATP + gamma-L-glutamyl-L-cysteine + beta-alanine = ADP + phosphate +
CA   gamma-L-glutamyl-L-cysteinyl-beta-alanine.
CC   -!- Not identical with EC 6.3.2.3.
//
ID   6.3.2.24
DE   Tyrosine--arginine ligase.
AN   Kyotorphin synthase.
AN   Kyotorphin-synthesizing enzyme.
AN   Tyrosyl-arginine synthase.
CA   ATP + L-tyrosine + L-arginine = AMP + diphosphate + L-tyrosyl-L-arginine.
//
ID   6.3.2.25
DE   Tubulin--tyrosine ligase.
AN   TTL.
CA   ATP + detyrosinated alpha-tubulin + L-tyrosine = alpha-tubulin + ADP +
CA   phosphate.
CC   -!- L-tyrosine is linked via a peptide bond to the C-terminus of
CC       de-tyrosinated alpha-tubulin (des-Tyr(omega)-alpha-tubulin).
CC   -!- The enzyme is highly specific for alpha-tubulin and moderately
CC       specific for ATP and L-tyrosine.
CC   -!- L-phenylalanine and 3,4-dihydroxy-L-phenylalanine are transferred but
CC       with higher Km values.
PR   PROSITE; PDOC51221;
DR   P38584, TTL_BOVIN  ;  Q8NG68, TTL_HUMAN  ;  P38585, TTL_MOUSE  ;
DR   P38160, TTL_PIG    ;  Q9QXJ0, TTL_RAT    ;  Q10438, TTL_SCHPO  ;
DR   P38254, TTL_YEAST  ;
//
ID   6.3.2.26
DE   N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase.
AN   ACV synthetase.
AN   L-alpha-aminoadipyl-cysteinyl-valine synthetase.
AN   L-delta-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase.
CA   L-2-aminohexanedioate + L-cysteine + L-valine + 3 ATP + H(2)O = N-(L-5-
CA   amino-5-carboxypentanoyl)-L-cysteinyl-D-valine + 3 AMP + 3 diphosphate.
CF   Magnesium.
CC   -!- The enzyme contains 4'-phosphopantetheine, which may be involved in
CC       the mechanism of the reaction.
CC   -!- Forms part of the penicillin biosynthesis pathway.
PR   PROSITE; PDOC00427;
DR   P19787, ACVS1_PENCH;  P26046, ACVS2_PENCH;  P25464, ACVS_CEPAC ;
DR   P27742, ACVS_EMENI ;  P27743, ACVS_NOCLA ;  Q01757, ACVS_STRCL ;
//
ID   6.3.2.27
DE   Aerobactin synthase.
CA   4 ATP + citrate + 2 N(6)-acetyl-N(6)-hydroxy-L-lysine + 2 H(2)O = 4 ADP +
CA   4 phosphate + aerobactin.
CF   Magnesium.
CC   -!- Aerobactin is one of a group of high-affinity iron chelators known as
CC       siderophores and is produced under conditions of iron deprivation.
CC   -!- It is a dihydroxamate comprising two molecules of N(6)-acetyl-N(6)-
CC       hydroxylysine and one molecule of citric acid.
CC   -!- This is the last of the three enzymes involved in its synthesis,
CC       the others being EC 1.14.13.59 and EC 2.3.1.102.
//
ID   6.3.2.28
DE   L-amino-acid alpha-ligase.
AN   Bacilysin synthetase.
AN   L-amino acid alpha-ligase.
AN   L-amino acid ligase.
CA   ATP + an L-amino acid + an L-amino acid = ADP + phosphate + L-aminoacyl-
CA   L-amino acid.
CF   Manganese or magnesium.
CC   -!- While the enzyme has extremely broad substrate specificity, it does
CC       not accept highly charged amino acids, such as Lys, Arg, Glu and Asp,
CC       nor does it react with secondary amines such as Pro.
CC   -!- The N-terminal residue of the alpha-dipeptide formed seems to be
CC       limited to Ala, Gly, Ser, Thr and Met (with Ala and Ser being the
CC       most preferred), whereas the C-terminal residue seems to allow for a
CC       wider variety of amino acids (but with a preference for Met and Phe).
CC   -!- However, not all combinations or dipeptides are formed; for example,
CC       while Ser is acceptable for the N-terminus and Thr for the
CC       C-terminus, a Ser-Thr dipeptide is not formed.
CC   -!- D-Ala, D-Ser and D-Phe are not substrates.
DR   Q8KWT3, BACD2_BACSU;  Q8KWS8, BACD_BACAM ;  P39641, BACD_BACSU ;
//
ID   6.3.2.29
DE   Cyanophycin synthase (L-aspartate-adding).
AN   Cyanophycin synthetase.
AN   Multi-L-arginyl-poly-L-aspartate synthase.
CA   ATP + (L-Asp(4-L-Arg))(n) + L-Asp = ADP + phosphate + (L-Asp(4-L-
CA   Arg))(n)-L-Asp.
CF   Magnesium.
CC   -!- Both this enzyme and EC 6.3.2.30 are required for the elongation of
CC       cyanophycin, which is a protein-like cell inclusion that is unique to
CC       cyanobacteria and acts as a temporary nitrogen store.
CC   -!- Both enzymes are found in the same protein but have different active
CC       sites.
CC   -!- Both L-Asp and L-Arg must be present before either enzyme will
CC       display significant activity.
PR   PROSITE; PDOC50975;
DR   O86109, CPHA_ANAVT ;  Q9KGY4, CPHA_CYAA5 ;  P58572, CPHA_NOSS1 ;
DR   P73833, CPHA_SYNY3 ;  P56947, CPHA_SYNY8 ;
//
ID   6.3.2.30
DE   Cyanophycin synthase (L-arginine-adding).
AN   Cyanophycin synthetase.
AN   Multi-L-arginyl-poly-L-aspartate synthase.
CA   ATP + (L-Asp(4-L-Arg))(n)-L-Asp + L-Arg = ADP + phosphate + (L-Asp(4-L-
CA   Arg))(n+1).
CF   Magnesium.
CC   -!- Both this enzyme and EC 6.3.2.29 are required for the elongation of
CC       cyanophycin, which is a protein-like cell inclusion that is unique to
CC       cyanobacteria and acts as a temporary nitrogen store.
CC   -!- Both enzymes are found in the same protein but have different active
CC       sites.
CC   -!- Both L-Asp and L-Arg must be present before either enzyme will
CC       display significant activity.
CC   -!- Canavanine and lysine can be incoporated into the polymer instead of
CC       arginine.
PR   PROSITE; PDOC50975;
DR   O86109, CPHA_ANAVT ;  Q9KGY4, CPHA_CYAA5 ;  P58572, CPHA_NOSS1 ;
DR   P73833, CPHA_SYNY3 ;  P56947, CPHA_SYNY8 ;
//
ID   6.3.2.31
DE   Coenzyme F420-0:L-glutamate ligase.
CA   GTP + coenzyme F420-0 + L-glutamate = GDP + phosphate + coenzyme F420-1.
CC   -!- This protein catalyzes the successive addition of two glutamate
CC       residues to cofactor F420 by two distinct and independent reactions.
CC   -!- In the reaction described here the enzyme attaches a glutamate via
CC       its alpha-amine group to F420-0.
CC   -!- In the second reaction (EC 6.3.2.34) it catalyzes the addition of a
CC       second L-glutamate residue to the gamma-carboxyl of the first
CC       glutamate.
//
ID   6.3.2.32
DE   Coenzyme gamma-F420-2:alpha-L-glutamate ligase.
CA   ATP + coenzyme gamma-F420-2 + L-glutamate = ADP + phosphate + coenzyme
CA   alpha-F420-3.
CC   -!- The enzyme caps the gamma-glutamyl tail of the hydride carrier
CC       coenzyme F420.
PR   PROSITE; PDOC50975;
//
ID   6.3.2.33
DE   Tetrahydrosarcinapterin synthase.
CA   ATP + tetrahydromethanopterin + L-glutamate = ADP + phosphate + 5,6,7,8-
CA   tetrahydrosarcinapterin.
CC   -!- This enzyme catalyzes the biosynthesis of 5,6,7,8-
CC       tetrahydrosarcinapterin, a modified form of tetrahydromethanopterin
CC       found in the Methanosarcinales.
CC   -!- It does not require K(+), and does not discriminate between ATP and
CC       GTP.
PR   PROSITE; PDOC50975;
DR   Q8TKX5, MPTN_METAC ;  Q58037, MPTN_METJA ;  Q8Q0M5, MPTN_METMA ;
DR   Q6LZC7, MPTN_METMP ;
//
ID   6.3.2.34
DE   Coenzyme F420-1:gamma-L-glutamate ligase.
CA   GTP + coenzyme F420-1 + L-glutamate = GDP + phosphate + coenzyme gamma-
CA   F420-2.
CC   -!- This protein catalyzes the successive addition of two glutamate
CC       residues to cofactor F420 by two distinct and independent reactions.
CC   -!- In the first reaction (EC 6.3.2.31) the enzyme attaches a glutamate
CC       via its alpha-amine group to F420-0.
CC   -!- In the second reaction, which is described here, the enzyme catalyzes
CC       the addition of a second L-glutamate residue to the gamma-carboxyl of
CC       the first glutamate.
//
ID   6.3.2.35
DE   D-alanine--D-serine ligase.
CA   D-alanine + D-serine + ATP = D-alanyl-D-serine + ADP + phosphate.
CC   -!- The product of this enzyme, D-alanyl-D-serine, can be incorporated
CC       into the peptidoglycan pentapeptide instead of the usual D-alanyl-D-
CC       alanine dipeptide, which is formed by EC 6.3.2.4, D-alanine--D-
CC       alanine ligase.
CC   -!- The resulting peptidoglycan does not bind the glycopeptide
CC       antibiotics vancomycin and teicoplanin, conferring resistance on the
CC       bacteria.
//
ID   6.3.2.36
DE   4-phosphopantoate--beta-alanine ligase.
AN   Phosphopantothenate synthetase.
CA   ATP + (R)-4-phosphopantoate + beta-alanine = AMP + diphosphate + (R)-
CA   4'-phosphopantothenate.
CC   -!- The conversion of (R)-pantoate to (R)-4'-phosphopantothenate is part
CC       of the pathway leading to biosynthesis of 4'-phosphopantetheine,
CC       an essential cofactor of coenzyme A and acyl-carrier protein.
CC   -!- In bacteria and eukaryotes this conversion is performed by
CC       condensation with beta-alanine, followed by phosphorylation
CC       (EC 6.3.2.1 and EC 2.7.1.33, respectively).
CC   -!- In archaea the order of these two steps is reversed,
CC       and phosphorylation precedes condensation with beta-alanine.
CC   -!- The two archaeal enzymes that catalyze this conversion are
CC       EC 2.7.1.169 and this enzyme.
DR   Q5JIZ8, PPS_PYRKO  ;
//
ID   6.3.2.37
DE   UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--D-lysine ligase.
AN   D-lysine-adding enzyme.
AN   UDP-MurNAc-L-Ala-D-Glu:D-Lys ligase.
CA   ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + D-lysine = ADP +
CA   phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-D-lysine.
CC   -!- The enzyme from Thermotoga maritima also performs the reaction of
CC       EC 6.3.2.7.
CC   -!- Involved in the synthesis of cell-wall peptidoglycan.
CC   -!- Formerly EC 6.3.2.n1.
DR   Q9WY79, MURE_THEMA ;
//
ID   6.3.2.n1
DE   Transferred entry: 6.3.2.37.
//
ID   6.3.2.n2
DE   Pup--protein ligase.
AN   Pup-conjugating enzyme.
CA   ATP + [Pup] + [protein]-lysine = ADP + phosphate + [protein]-N-
CA   pupyllysine.
CC   -!- The enzyme catalyzes the covalent attachment of the prokaryotic
CC       ubiquitin-like protein modifier Pup to the proteasomal substrate
CC       proteins, thereby targeting them for proteasomal degradation.
CC   -!- This tagging system is termed pupylation.
CC   -!- The ligation reaction involves the side-chain carboxylate of the
CC       C-terminal glutamate of Pup and the side-chain amino group of a
CC       substrate lysine.
CC   -!- PafA is required to confer resistance against the lethal effects of
CC       reactive nitrogen intermediates (RNI), antimicrobial molecules
CC       produced by activated macrophages and other cell types.
DR   P72263, PAFA1_RHOER;  P72270, PAFA2_RHOER;  A0LU53, PAFA_ACIC1 ;
DR   C7LYP9, PAFA_ACIFD ;  C6WIE4, PAFA_ACTMD ;  A1R6Q9, PAFA_ARTAT ;
DR   B8H8L8, PAFA_ARTCA ;  A0JWY8, PAFA_ARTS2 ;  B8DTX8, PAFA_BIFA0 ;
DR   A1A0U7, PAFA_BIFAA ;  C6AHX4, PAFA_BIFAS ;  D2Q9D0, PAFA_BIFDB ;
DR   C6A7B6, PAFA_BIFLB ;  B3DRN8, PAFA_BIFLD ;  Q8G3G3, PAFA_BIFLO ;
DR   B7GUN9, PAFA_BIFLS ;  C7MCY7, PAFA_BRAFD ;  C7PVV4, PAFA_CATAD ;
DR   C3PGA3, PAFA_CORA7 ;  Q6NH95, PAFA_CORDI ;  Q8FTE6, PAFA_COREF ;
DR   A4QE80, PAFA_CORGB ;  Q8NQE1, PAFA_CORGL ;  Q4JVP8, PAFA_CORJK ;
DR   C4LIK9, PAFA_CORK4 ;  B1VDV5, PAFA_CORU7 ;  Q0RLT2, PAFA_FRAAA ;
DR   Q2J9R8, PAFA_FRASC ;  A8LH49, PAFA_FRASN ;  D2S6E4, PAFA_GEOOG ;
DR   D0LDT3, PAFA_GORB4 ;  C7R405, PAFA_JONDD ;  A6W972, PAFA_KINRD ;
DR   B2GIN9, PAFA_KOCRD ;  D2Q3K3, PAFA_KRIFD ;  C5CBV0, PAFA_MICLC ;
DR   A0QFB7, PAFA_MYCA1 ;  B1MAJ3, PAFA_MYCA9 ;  P64944, PAFA_MYCBO ;
DR   A1KKE3, PAFA_MYCBP ;  C1AQ16, PAFA_MYCBT ;  A4TB47, PAFA_MYCGI ;
DR   B8ZRF5, PAFA_MYCLB ;  P54077, PAFA_MYCLE ;  B2HFV4, PAFA_MYCMM ;
DR   Q73YX0, PAFA_MYCPA ;  A0QZ42, PAFA_MYCS2 ;  A3PZG1, PAFA_MYCSJ ;
DR   A1UFV1, PAFA_MYCSK ;  Q1B959, PAFA_MYCSS ;  A5U4C3, PAFA_MYCTA ;
DR   A5WP74, PAFA_MYCTF ;  C6DPW7, PAFA_MYCTK ;  P64943, PAFA_MYCTU ;
DR   A0PQT1, PAFA_MYCUA ;  A1TAP0, PAFA_MYCVP ;  C8XAP5, PAFA_NAKMY ;
DR   Q5YUX4, PAFA_NOCFA ;  A1SK16, PAFA_NOCSJ ;  A9WSH9, PAFA_RENSM ;
DR   C0ZZU4, PAFA_RHOE4 ;  C1ASP4, PAFA_RHOOB ;  Q0SIG2, PAFA_RHOSR ;
DR   D2NT93, PAFA_ROTMD ;  A4FBY4, PAFA_SACEN ;  C7MWV3, PAFA_SACVD ;
DR   A8M2A6, PAFA_SALAI ;  A4X747, PAFA_SALTO ;  D1BHT7, PAFA_SANKS ;
DR   Q828I4, PAFA_STRAW ;  Q9RJ61, PAFA_STRCO ;  B1W310, PAFA_STRGG ;
DR   D2ATU8, PAFA_STRRD ;  C9Z4D4, PAFA_STRSW ;  D1A2T1, PAFA_THECD ;
DR   Q47NZ6, PAFA_THEFY ;  D1BS28, PAFA_XYLCX ;
//
ID   6.3.2.n3
DE   ISG15--protein ligase.
AN   ISG15-conjugating enzyme.
CA   ATP + [ISG15] + [protein]-lysine = AMP + diphosphate + [protein]-N-
CA   ISGyllysine.
CC   -!- The enzyme from human also functions as ubiquitin--protein ligase
CC       (EC 6.3.2.19).
DR   Q14258, TRI25_HUMAN;  Q61510, TRI25_MOUSE;
//
ID   6.3.2.n4
DE   Alpha-aminoadipate--LysW ligase.
AN   AAA--LysW ligase.
CA   ATP + [lysW] + L-2-aminoadipate = ADP + phosphate + [lysW]-L-2-
CA   aminoadipate.
CC   -!- The enzyme ligates the L-2-aminoadipate to the C-terminal glutamate
CC       residue of LysW.
CC   -!- This is the first step in the AAA pathway of L-lysine biosynthesis.
DR   Q7SI95, LYSX_SULSO ;  Q976J9, LYSX_SULTO ;  Q5SH23, LYSX_THET8 ;
//
ID   6.3.2.n5
DE   Pantoate--beta-alanine ligase (ADP-forming).
AN   Pantothenate synthetase.
CA   ATP + (R)-pantoate + beta-alanine = ADP + phosphate + (R)-pantothenate.
CC   -!- The enzyme is found in Archaea.
DR   Q57662, PASYA_METJA;  Q8PUQ1, PASYA_METMA;
//
ID   6.3.3.1
DE   Phosphoribosylformylglycinamidine cyclo-ligase.
AN   AIR synthase.
AN   AIR synthetase.
AN   AIRS.
AN   Phosphoribosyl-aminoimidazole synthetase.
AN   Phosphoribosylaminoimidazole synthetase.
CA   ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP +
CA   phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.
DR   Q59A32, PUR2_BOVIN ;  P21872, PUR2_CHICK ;  Q26255, PUR2_CHITE ;
DR   Q54GJ2, PUR2_DICDI ;  P00967, PUR2_DROME ;  P16340, PUR2_DROPS ;
DR   P22102, PUR2_HUMAN ;  Q64737, PUR2_MOUSE ;  P20772, PUR2_SCHPO ;
DR   Q99148, PUR2_YARLI ;  P07244, PUR2_YEAST ;  Q6F973, PUR5_ACIAD ;
DR   B7GY98, PUR5_ACIB3 ;  B7I5C6, PUR5_ACIB5 ;  B2HWV2, PUR5_ACIBC ;
DR   B0VT70, PUR5_ACIBS ;  A3M7X8, PUR5_ACIBT ;  B0VDJ1, PUR5_ACIBY ;
DR   A3N1A1, PUR5_ACTP2 ;  B0BQ30, PUR5_ACTPJ ;  A6VMA4, PUR5_ACTSZ ;
DR   A0KM24, PUR5_AERHH ;  A4SL28, PUR5_AERS4 ;  B9JCV0, PUR5_AGRRK ;
DR   Q8UG98, PUR5_AGRT5 ;  B9JUY3, PUR5_AGRVS ;  Q0VP77, PUR5_ALCBS ;
DR   Q0ABB7, PUR5_ALHEH ;  B6EJU3, PUR5_ALISL ;  A6TLS5, PUR5_ALKMQ ;
DR   A8MLI7, PUR5_ALKOO ;  B4RZX7, PUR5_ALTMD ;  B8JDJ0, PUR5_ANAD2 ;
DR   Q2IQE7, PUR5_ANADE ;  A7HDB7, PUR5_ANADF ;  B4UGX9, PUR5_ANASK ;
DR   B9MS91, PUR5_ANATD ;  Q05728, PUR5_ARATH ;  O28580, PUR5_ARCFU ;
DR   Q5NXR0, PUR5_AROAE ;  A1KA97, PUR5_AZOSB ;  C1DRW0, PUR5_AZOVD ;
DR   A7Z251, PUR5_BACA2 ;  C3PBN2, PUR5_BACAA ;  C3L534, PUR5_BACAC ;
DR   A0R8Z8, PUR5_BACAH ;  Q81ZH0, PUR5_BACAN ;  B7JM87, PUR5_BACC0 ;
DR   Q73EN3, PUR5_BACC1 ;  B7IUV5, PUR5_BACC2 ;  C1EV65, PUR5_BACC3 ;
DR   B7H4T8, PUR5_BACC4 ;  B7HS34, PUR5_BACC7 ;  A7GKI0, PUR5_BACCN ;
DR   B9J1K7, PUR5_BACCQ ;  Q81IQ1, PUR5_BACCR ;  Q63GT1, PUR5_BACCZ ;
DR   Q9KF55, PUR5_BACHD ;  Q6HPA2, PUR5_BACHK ;  Q65MS6, PUR5_BACLD ;
DR   A8FAM9, PUR5_BACP2 ;  Q5WJ84, PUR5_BACSK ;  P12043, PUR5_BACSU ;
DR   A9VRF3, PUR5_BACWK ;  Q6G5R9, PUR5_BARHE ;  Q6FZK1, PUR5_BARQU ;
DR   A9IVF6, PUR5_BART1 ;  B2IJR2, PUR5_BEII9 ;  B8DTT6, PUR5_BIFA0 ;
DR   A1A0R8, PUR5_BIFAA ;  B3DT56, PUR5_BIFLD ;  Q8G595, PUR5_BIFLO ;
DR   B7GU81, PUR5_BIFLS ;  Q2KX26, PUR5_BORA1 ;  Q7WG60, PUR5_BORBR ;
DR   Q7W4N4, PUR5_BORPA ;  A9I602, PUR5_BORPD ;  Q7W0A7, PUR5_BORPE ;
DR   C0ZKC8, PUR5_BREBN ;  B2S4W8, PUR5_BRUA1 ;  Q2YN59, PUR5_BRUA2 ;
DR   Q57E30, PUR5_BRUAB ;  A9MA84, PUR5_BRUC2 ;  C0RI52, PUR5_BRUMB ;
DR   Q8YGB9, PUR5_BRUME ;  A5VPP4, PUR5_BRUO2 ;  B0CL36, PUR5_BRUSI ;
DR   Q8G1K5, PUR5_BRUSU ;  B1YTV3, PUR5_BURA4 ;  Q1BYW4, PUR5_BURCA ;
DR   B1JW28, PUR5_BURCC ;  A0K4T7, PUR5_BURCH ;  B4EDH7, PUR5_BURCJ ;
DR   Q0BI09, PUR5_BURCM ;  A9AGA9, PUR5_BURM1 ;  A3MN88, PUR5_BURM7 ;
DR   A2S554, PUR5_BURM9 ;  Q62HE4, PUR5_BURMA ;  A1V0V7, PUR5_BURMS ;
DR   A3NYW6, PUR5_BURP0 ;  Q3JP21, PUR5_BURP1 ;  A3ND57, PUR5_BURP6 ;
DR   B2JGD2, PUR5_BURP8 ;  B2T067, PUR5_BURPP ;  Q63R55, PUR5_BURPS ;
DR   Q39JB9, PUR5_BURS3 ;  Q2SYY5, PUR5_BURTA ;  A4JBT0, PUR5_BURVG ;
DR   Q145C6, PUR5_BURXL ;  A4XKZ4, PUR5_CALS8 ;  Q3AD62, PUR5_CARHZ ;
DR   Q1QVP5, PUR5_CHRSD ;  Q7NS12, PUR5_CHRVO ;  Q97J93, PUR5_CLOAB ;
DR   A7FXD5, PUR5_CLOB1 ;  C3L2V1, PUR5_CLOB6 ;  C1FV78, PUR5_CLOBJ ;
DR   B1IL59, PUR5_CLOBK ;  A7GH98, PUR5_CLOBL ;  B1KZ57, PUR5_CLOBM ;
DR   B8I492, PUR5_CLOCE ;  B9E4K8, PUR5_CLOK1 ;  A5N0Q2, PUR5_CLOK5 ;
DR   A0Q1J2, PUR5_CLONN ;  Q0TTB2, PUR5_CLOP1 ;  Q8XMK4, PUR5_CLOPE ;
DR   A9KHX3, PUR5_CLOPH ;  Q892X1, PUR5_CLOTE ;  A3DEV1, PUR5_CLOTH ;
DR   Q47Z78, PUR5_COLP3 ;  A9KBZ3, PUR5_COXBN ;  A9NA98, PUR5_COXBR ;
DR   Q83AZ0, PUR5_COXBU ;  Q0K769, PUR5_CUPNH ;  Q46XJ9, PUR5_CUPPJ ;
DR   B3R6D1, PUR5_CUPTR ;  B1WPZ0, PUR5_CYAA5 ;  B8HPV7, PUR5_CYAP4 ;
DR   B7KJK8, PUR5_CYAP7 ;  B7K0I0, PUR5_CYAP8 ;  Q47B77, PUR5_DECAR ;
DR   B8FJY6, PUR5_DESAA ;  Q311C7, PUR5_DESDG ;  B8FP03, PUR5_DESHD ;
DR   Q24QH4, PUR5_DESHY ;  Q6AK63, PUR5_DESPS ;  B8DNV5, PUR5_DESVM ;
DR   A8LNB8, PUR5_DINSH ;  A7ZPU2, PUR5_ECO24 ;  B7UGN7, PUR5_ECO27 ;
DR   B7MHY0, PUR5_ECO45 ;  B7LCN9, PUR5_ECO55 ;  Q8XAC5, PUR5_ECO57 ;
DR   B5Z036, PUR5_ECO5E ;  B7NQN8, PUR5_ECO7I ;  B7MYC7, PUR5_ECO81 ;
DR   B7M7K3, PUR5_ECO8A ;  C4ZX74, PUR5_ECOBW ;  B1XAX4, PUR5_ECODH ;
DR   A8A2Z1, PUR5_ECOHS ;  Q0TEY9, PUR5_ECOL5 ;  Q8FF72, PUR5_ECOL6 ;
DR   B1IWG1, PUR5_ECOLC ;  P08178, PUR5_ECOLI ;  B7N681, PUR5_ECOLU ;
DR   B6I571, PUR5_ECOSE ;  B1LNF0, PUR5_ECOSM ;  Q1R8N9, PUR5_ECOUT ;
DR   C5BHQ4, PUR5_EDWI9 ;  A4WD72, PUR5_ENT38 ;  Q833Z1, PUR5_ENTFA ;
DR   A7ML12, PUR5_ENTS8 ;  Q6D7S1, PUR5_ERWCT ;  B2VE71, PUR5_ERWT9 ;
DR   Q2N8X9, PUR5_ERYLH ;  B7LKE3, PUR5_ESCF3 ;  C4Z478, PUR5_EUBE2 ;
DR   C4ZH75, PUR5_EUBR3 ;  B1YJ07, PUR5_EXIS2 ;  C4L2A1, PUR5_EXISA ;
DR   B0S0R2, PUR5_FINM2 ;  Q8REV3, PUR5_FUSNN ;  B5EFU7, PUR5_GEOBB ;
DR   Q5L3D0, PUR5_GEOKA ;  B3E3K3, PUR5_GEOLS ;  Q39UK1, PUR5_GEOMG ;
DR   B9M1P4, PUR5_GEOSF ;  Q74CB6, PUR5_GEOSL ;  C6E6M9, PUR5_GEOSM ;
DR   C5D4I2, PUR5_GEOSW ;  A4IJX5, PUR5_GEOTN ;  A5G3H3, PUR5_GEOUR ;
DR   Q7NMP5, PUR5_GLOVI ;  Q4QKF3, PUR5_HAEI8 ;  A5UC39, PUR5_HAEIE ;
DR   A5UEU3, PUR5_HAEIG ;  P43848, PUR5_HAEIN ;  B8F5E6, PUR5_HAEPS ;
DR   Q0I5D1, PUR5_HAES1 ;  B0URN5, PUR5_HAES2 ;  Q2SKT3, PUR5_HAHCH ;
DR   C4K4D1, PUR5_HAMD5 ;  Q5QUP9, PUR5_IDILO ;  Q28RA9, PUR5_JANSC ;
DR   B5XNQ0, PUR5_KLEP3 ;  A6TCB3, PUR5_KLEP7 ;  Q5FIV3, PUR5_LACAC ;
DR   Q1G9G0, PUR5_LACDA ;  Q049L9, PUR5_LACDB ;  B2GF76, PUR5_LACF3 ;
DR   A8YW83, PUR5_LACH4 ;  Q9CFF4, PUR5_LACLA ;  O68186, PUR5_LACLM ;
DR   A5VHU0, PUR5_LACRD ;  B2G5C0, PUR5_LACRJ ;  Q1WU57, PUR5_LACS1 ;
DR   Q93MM7, PUR5_LACSS ;  C1DC84, PUR5_LARHH ;  Q1MRM4, PUR5_LAWIP ;
DR   Q72T98, PUR5_LEPIC ;  Q8F242, PUR5_LEPIN ;  Q92AP1, PUR5_LISIN ;
DR   C1KW66, PUR5_LISMC ;  Q71YQ1, PUR5_LISMF ;  B8DDZ0, PUR5_LISMH ;
DR   Q8Y6C3, PUR5_LISMO ;  A0AJM1, PUR5_LISW6 ;  B1HTV6, PUR5_LYSSC ;
DR   B9EAZ0, PUR5_MACCJ ;  A0LA23, PUR5_MAGSM ;  Q65UX7, PUR5_MANSM ;
DR   A1TZ73, PUR5_MARAV ;  Q11GW6, PUR5_MESSB ;  Q8TUD7, PUR5_METAC ;
DR   Q46E56, PUR5_METBF ;  Q12UL8, PUR5_METBU ;  Q60BU2, PUR5_METCA ;
DR   Q1H4W1, PUR5_METFK ;  Q57656, PUR5_METJA ;  Q8TW12, PUR5_METKA ;
DR   A4FWS4, PUR5_METM5 ;  A9AA59, PUR5_METM6 ;  A6VGJ3, PUR5_METM7 ;
DR   Q8PX06, PUR5_METMA ;  Q6LXU3, PUR5_METMP ;  B8IP71, PUR5_METNO ;
DR   A5UM16, PUR5_METS3 ;  B0UKC4, PUR5_METS4 ;  B8EJY5, PUR5_METSB ;
DR   O27272, PUR5_METTH ;  A6UPQ3, PUR5_METVS ;  B0JTF5, PUR5_MICAN ;
DR   Q2RGU7, PUR5_MOOTA ;  Q1D8V5, PUR5_MYXXD ;  Q5F973, PUR5_NEIG1 ;
DR   A9LZD2, PUR5_NEIM0 ;  Q9JUA2, PUR5_NEIMA ;  Q9JZ80, PUR5_NEIMB ;
DR   A1KU60, PUR5_NEIMF ;  Q0ADT8, PUR5_NITEC ;  Q82Y02, PUR5_NITEU ;
DR   Q1QLI2, PUR5_NITHX ;  Q2Y5R7, PUR5_NITMU ;  Q3JBW2, PUR5_NITOC ;
DR   Q3SS83, PUR5_NITWN ;  Q2G9X9, PUR5_NOVAD ;  Q8ES94, PUR5_OCEIH ;
DR   A6X235, PUR5_OCHA4 ;  A7HYF2, PUR5_PARL1 ;  Q9CPL6, PUR5_PASMU ;
DR   C6DBR0, PUR5_PECCP ;  Q3A515, PUR5_PELCD ;  Q7N3F7, PUR5_PHOLL ;
DR   Q6LN73, PUR5_PHOPR ;  Q126R8, PUR5_POLSJ ;  A3PF79, PUR5_PROM0 ;
DR   A2C535, PUR5_PROM1 ;  A8G794, PUR5_PROM2 ;  A2CBX4, PUR5_PROM3 ;
DR   A9BCS9, PUR5_PROM4 ;  Q318F3, PUR5_PROM9 ;  Q7V9S9, PUR5_PROMA ;
DR   B4EY89, PUR5_PROMH ;  Q7V581, PUR5_PROMM ;  Q7UZR7, PUR5_PROMP ;
DR   A2BTH0, PUR5_PROMS ;  Q46IM4, PUR5_PROMT ;  Q48FI4, PUR5_PSE14 ;
DR   Q15SY3, PUR5_PSEA6 ;  B7UXY9, PUR5_PSEA8 ;  Q02IA6, PUR5_PSEAB ;
DR   Q9I513, PUR5_PSEAE ;  Q1IDL2, PUR5_PSEE4 ;  Q4K8A5, PUR5_PSEF5 ;
DR   C3K102, PUR5_PSEFS ;  Q3IIQ2, PUR5_PSEHT ;  A4XWN5, PUR5_PSEMY ;
DR   A5W7R7, PUR5_PSEP1 ;  Q3KFT0, PUR5_PSEPF ;  B0KT52, PUR5_PSEPG ;
DR   Q88MA9, PUR5_PSEPK ;  B1J1M3, PUR5_PSEPW ;  Q885Y1, PUR5_PSESM ;
DR   Q4ZQ51, PUR5_PSEU2 ;  Q4FR86, PUR5_PSYA2 ;  Q1Q9M0, PUR5_PSYCK ;
DR   Q9UY56, PUR5_PYRAB ;  Q8U3M6, PUR5_PYRFU ;  O58054, PUR5_PYRHO ;
DR   Q5JFN7, PUR5_PYRKO ;  Q1LJ92, PUR5_RALME ;  Q8XW52, PUR5_RALSO ;
DR   B3PV93, PUR5_RHIE6 ;  Q2KA45, PUR5_RHIEC ;  Q1MIW9, PUR5_RHIL3 ;
DR   Q9XAT2, PUR5_RHILE ;  Q984K6, PUR5_RHILO ;  B5ZX12, PUR5_RHILW ;
DR   Q92QW2, PUR5_RHIME ;  C3M9F7, PUR5_RHISN ;  Q7UI59, PUR5_RHOBA ;
DR   Q21VH4, PUR5_RHOFD ;  Q6N5C8, PUR5_RHOPA ;  Q215Q6, PUR5_RHOPB ;
DR   Q2RSC8, PUR5_RHORT ;  A3PHH4, PUR5_RHOS1 ;  Q3J517, PUR5_RHOS4 ;
DR   A4WX36, PUR5_RHOS5 ;  B9KMR6, PUR5_RHOSK ;  Q167K4, PUR5_ROSDO ;
DR   Q21MC3, PUR5_SACD2 ;  Q57LL0, PUR5_SALCH ;  B5FQJ2, PUR5_SALDC ;
DR   B4TD75, PUR5_SALHS ;  Q5PNJ8, PUR5_SALPA ;  C0PYQ6, PUR5_SALPC ;
DR   B5BB05, PUR5_SALPK ;  B4TR76, PUR5_SALSV ;  Q8Z4R2, PUR5_SALTI ;
DR   P74883, PUR5_SALTY ;  A1S7E6, PUR5_SHEAM ;  B8EAL4, PUR5_SHEB2 ;
DR   A3D3D1, PUR5_SHEB5 ;  A6WM34, PUR5_SHEB8 ;  A9KY38, PUR5_SHEB9 ;
DR   Q12MF0, PUR5_SHEDO ;  Q084L1, PUR5_SHEFN ;  B0TPW7, PUR5_SHEHH ;
DR   A3QD32, PUR5_SHELP ;  Q8EDI8, PUR5_SHEON ;  A8H5R0, PUR5_SHEPA ;
DR   A4Y5T8, PUR5_SHEPC ;  B8CN80, PUR5_SHEPW ;  A0KYA3, PUR5_SHESA ;
DR   A8FUD3, PUR5_SHESH ;  Q0HHL6, PUR5_SHESM ;  Q0HTW8, PUR5_SHESR ;
DR   A1RKQ5, PUR5_SHESW ;  B1KIG9, PUR5_SHEWM ;  B2TXS4, PUR5_SHIB3 ;
DR   Q31XZ3, PUR5_SHIBS ;  Q32D69, PUR5_SHIDS ;  Q0T221, PUR5_SHIF8 ;
DR   Q83QL4, PUR5_SHIFL ;  Q3YZ53, PUR5_SHISS ;  Q5LRF9, PUR5_SILPO ;
DR   Q1GGK7, PUR5_SILST ;  A6U7L8, PUR5_SINMW ;  Q2NS68, PUR5_SODGM ;
DR   A9FYZ4, PUR5_SORC5 ;  Q1GSA2, PUR5_SPHAL ;  A7X0W4, PUR5_STAA1 ;
DR   A6U0N9, PUR5_STAA2 ;  Q2FI07, PUR5_STAA3 ;  Q2FZI8, PUR5_STAA8 ;
DR   A5IRV8, PUR5_STAA9 ;  Q2YX52, PUR5_STAAB ;  Q5HH13, PUR5_STAAC ;
DR   A6QFS9, PUR5_STAAE ;  P67721, PUR5_STAAM ;  P99163, PUR5_STAAN ;
DR   Q6GI13, PUR5_STAAR ;  Q6GAE2, PUR5_STAAS ;  A8Z1L3, PUR5_STAAT ;
DR   Q8NX90, PUR5_STAAW ;  B9DQ40, PUR5_STACT ;  Q5HQ99, PUR5_STAEQ ;
DR   Q8CT29, PUR5_STAES ;  Q4L580, PUR5_STAHJ ;  Q49WJ5, PUR5_STAS1 ;
DR   Q3K400, PUR5_STRA1 ;  Q8E7W9, PUR5_STRA3 ;  Q8E2G1, PUR5_STRA5 ;
DR   P40178, PUR5_STRFR ;  A8AU99, PUR5_STRGC ;  B4SN29, PUR5_STRM5 ;
DR   B2FRX8, PUR5_STRMK ;  Q8DWL1, PUR5_STRMU ;  Q9A1Z0, PUR5_STRP1 ;
DR   Q04N22, PUR5_STRP2 ;  P0DD62, PUR5_STRP3 ;  B5E5J6, PUR5_STRP4 ;
DR   Q5XEF4, PUR5_STRP6 ;  C1C9V1, PUR5_STRP7 ;  Q8P312, PUR5_STRP8 ;
DR   Q1JE80, PUR5_STRPB ;  Q1JP36, PUR5_STRPC ;  Q1JJ82, PUR5_STRPD ;
DR   Q1J936, PUR5_STRPF ;  A2RBZ5, PUR5_STRPG ;  B1I7V5, PUR5_STRPI ;
DR   B8ZJN0, PUR5_STRPJ ;  Q48VX3, PUR5_STRPM ;  Q97TA2, PUR5_STRPN ;
DR   P0DD63, PUR5_STRPQ ;  B2IR37, PUR5_STRPS ;  B5XJ18, PUR5_STRPZ ;
DR   Q8DRM4, PUR5_STRR6 ;  Q9F1T6, PUR5_STRSU ;  A3CJZ4, PUR5_STRSV ;
DR   Q5M203, PUR5_STRT1 ;  Q5M6J5, PUR5_STRT2 ;  Q03MZ8, PUR5_STRTD ;
DR   B9DSR4, PUR5_STRU0 ;  C1CBM4, PUR5_STRZJ ;  C1CHV9, PUR5_STRZP ;
DR   C1CNS6, PUR5_STRZT ;  Q9UX29, PUR5_SULSO ;  Q970V2, PUR5_SULTO ;
DR   Q67KG0, PUR5_SYMTH ;  Q2LTT5, PUR5_SYNAS ;  Q31PY7, PUR5_SYNE7 ;
DR   Q2JQY9, PUR5_SYNJA ;  Q2JL07, PUR5_SYNJB ;  B1XNH7, PUR5_SYNP2 ;
DR   Q5N490, PUR5_SYNP6 ;  A5GIY3, PUR5_SYNPW ;  Q7U4N8, PUR5_SYNPX ;
DR   A5GVR5, PUR5_SYNR3 ;  Q0ICW4, PUR5_SYNS3 ;  Q3AUU9, PUR5_SYNS9 ;
DR   Q3AMJ2, PUR5_SYNSC ;  Q0AW29, PUR5_SYNWW ;  Q55422, PUR5_SYNY3 ;
DR   C5BP01, PUR5_TERTT ;  Q9HLY3, PUR5_THEAC ;  Q8DHY2, PUR5_THEEB ;
DR   C5A4H7, PUR5_THEGJ ;  A8F8I1, PUR5_THELT ;  B0KBQ3, PUR5_THEP3 ;
DR   B0K3Q6, PUR5_THEPX ;  Q8RC57, PUR5_THETN ;  Q97CD7, PUR5_THEVO ;
DR   B5YKG0, PUR5_THEYD ;  Q31GT2, PUR5_THICR ;  C4LC65, PUR5_TOLAT ;
DR   A5F643, PUR5_VIBC3 ;  Q9KPY6, PUR5_VIBCH ;  C3LPN0, PUR5_VIBCM ;
DR   Q5E3H3, PUR5_VIBF1 ;  B5FGY5, PUR5_VIBFM ;  A7MY25, PUR5_VIBHB ;
DR   Q87MH0, PUR5_VIBPA ;  B7VIN4, PUR5_VIBSL ;  Q8DBC2, PUR5_VIBVU ;
DR   Q7MIK1, PUR5_VIBVY ;  P52424, PUR5_VIGUN ;  Q8PID9, PUR5_XANAC ;
DR   Q3BQX8, PUR5_XANC5 ;  Q4UX30, PUR5_XANC8 ;  B0RQI6, PUR5_XANCB ;
DR   Q8P725, PUR5_XANCP ;  Q2P674, PUR5_XANOM ;  B2SJY0, PUR5_XANOP ;
DR   Q5H3C0, PUR5_XANOR ;  Q9PFS0, PUR5_XYLFA ;  Q87B94, PUR5_XYLFT ;
DR   A1JKZ7, PUR5_YERE8 ;  A7FG37, PUR5_YERP3 ;  Q1C5P2, PUR5_YERPA ;
DR   B2K9K0, PUR5_YERPB ;  Q8ZCX8, PUR5_YERPE ;  A9QZW5, PUR5_YERPG ;
DR   Q1CK40, PUR5_YERPN ;  A4TMP3, PUR5_YERPP ;  Q668E5, PUR5_YERPS ;
DR   B1JSF4, PUR5_YERPY ;
//
ID   6.3.3.2
DE   5-formyltetrahydrofolate cyclo-ligase.
AN   5,10-methenyltetrahydrofolate synthetase.
AN   5-Formyltetrahydrofolate cyclodehydrase.
AN   Methenyl-THF synthetase.
CA   ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-
CA   methenyltetrahydrofolate.
DR   Q9P7W2, FTHC_SCHPO ;  P40099, FTHC_YEAST ;  Q9XWE6, MTHFS_CAEEL;
DR   P49914, MTHFS_HUMAN;  Q9D110, MTHFS_MOUSE;  P47487, MTHFS_MYCGE;
DR   P75430, MTHFS_MYCPN;  P80405, MTHFS_RABIT;
//
ID   6.3.3.3
DE   Dethiobiotin synthase.
AN   DTB synthetase.
CA   ATP + 7,8-diaminononanoate + CO(2) = ADP + phosphate + dethiobiotin.
CC   -!- CTP has half the activity of ATP.
DR   Q2KXN6, BIOCD_BORA1;  Q8X821, BIOD1_ECO57;  P13000, BIOD1_ECOLI;
DR   Q7VLG6, BIOD1_HAEDU;  P45209, BIOD1_HAEIN;  Q9CN08, BIOD1_PASMU;
DR   Q8Z890, BIOD1_SALTI;  Q8ZQQ5, BIOD1_SALTY;  Q8ZGW9, BIOD1_YERPE;
DR   P0A6F0, BIOD2_ECO57;  P0A6E9, BIOD2_ECOLI;  Q7VL12, BIOD2_HAEDU;
DR   P45248, BIOD2_HAEIN;  Q9CJT7, BIOD2_PASMU;  Q8Z6X9, BIOD2_SALTI;
DR   Q8ZPK6, BIOD2_SALTY;  P69953, BIOD2_YERPE;  A5FZN7, BIOD_ACICJ ;
DR   A6VND6, BIOD_ACTSZ ;  A0KIC9, BIOD_AERHH ;  A4SPR4, BIOD_AERS4 ;
DR   Q8U8T9, BIOD_AGRT5 ;  B2UNC5, BIOD_AKKM8 ;  B6ESC4, BIOD_ALISL ;
DR   B4S0P6, BIOD_ALTMD ;  B8J7V5, BIOD_ANAD2 ;  Q2IM14, BIOD_ANADE ;
DR   A7H6E5, BIOD_ANADF ;  B4UKM8, BIOD_ANASK ;  B9MP52, BIOD_ANATD ;
DR   B7GHM4, BIOD_ANOFW ;  O66832, BIOD_AQUAE ;  Q5NZF8, BIOD_AROAE ;
DR   A7Z5B3, BIOD_BACA2 ;  C3P7Q4, BIOD_BACAA ;  C3LJP5, BIOD_BACAC ;
DR   A0RIC0, BIOD_BACAH ;  Q81MA9, BIOD_BACAN ;  B7JLX3, BIOD_BACC0 ;
DR   B7IWN2, BIOD_BACC2 ;  C1EQZ2, BIOD_BACC3 ;  B7HAZ1, BIOD_BACC4 ;
DR   Q818W9, BIOD_BACCR ;  Q635G3, BIOD_BACCZ ;  Q9KER6, BIOD_BACHD ;
DR   Q6HE47, BIOD_BACHK ;  Q65ML0, BIOD_BACLD ;  Q8KZM8, BIOD_BACNA ;
DR   P53558, BIOD_BACSU ;  Q1LTL5, BIOD_BAUCH ;  C0QVL9, BIOD_BRAHW ;
DR   Q9AMS4, BIOD_BRAJA ;  A5EFG7, BIOD_BRASB ;  B2SBF2, BIOD_BRUA1 ;
DR   Q2YKB6, BIOD_BRUA2 ;  Q577P6, BIOD_BRUAB ;  A9MBD4, BIOD_BRUC2 ;
DR   C0RL24, BIOD_BRUMB ;  Q8YBV9, BIOD_BRUME ;  A5VUF9, BIOD_BRUO2 ;
DR   A9WYH0, BIOD_BRUSI ;  Q8FWG5, BIOD_BRUSU ;  B8D982, BIOD_BUCA5 ;
DR   P57377, BIOD_BUCAI ;  P59564, BIOD_BUCBP ;  B1YNS1, BIOD_BURA4 ;
DR   Q1BT35, BIOD_BURCA ;  B1JZE0, BIOD_BURCC ;  A0KB04, BIOD_BURCH ;
DR   B4E9L5, BIOD_BURCJ ;  Q0BBD5, BIOD_BURCM ;  A9AE45, BIOD_BURM1 ;
DR   A3MNG2, BIOD_BURM7 ;  A2S7R2, BIOD_BURM9 ;  Q62MX0, BIOD_BURMA ;
DR   A1V818, BIOD_BURMS ;  A3NQS2, BIOD_BURP0 ;  Q3JWR7, BIOD_BURP1 ;
DR   A3N521, BIOD_BURP6 ;  B2JKH5, BIOD_BURP8 ;  Q63Y24, BIOD_BURPS ;
DR   Q39CE5, BIOD_BURS3 ;  Q2T1Q3, BIOD_BURTA ;  A4JIB6, BIOD_BURVG ;
DR   A4XGB6, BIOD_CALS8 ;  A8FK97, BIOD_CAMJ8 ;  Q9PIJ1, BIOD_CAMJE ;
DR   A1VY27, BIOD_CAMJJ ;  Q5HWG3, BIOD_CAMJR ;  B8GVE1, BIOD_CAUCN ;
DR   Q9A7Z2, BIOD_CAUCR ;  B0SZT0, BIOD_CAUSK ;  B3PI90, BIOD_CELJU ;
DR   Q5L5F7, BIOD_CHLAB ;  Q255H0, BIOD_CHLFF ;  Q9Z6L7, BIOD_CHLPN ;
DR   Q8KGC0, BIOD_CHLTE ;  Q1QYD9, BIOD_CHRSD ;  Q97JC5, BIOD_CLOAB ;
DR   A7FVS5, BIOD_CLOB1 ;  C3KZ35, BIOD_CLOB6 ;  B2V168, BIOD_CLOBA ;
DR   B2TL74, BIOD_CLOBB ;  A5I426, BIOD_CLOBH ;  C1FR34, BIOD_CLOBJ ;
DR   B1IHH8, BIOD_CLOBK ;  A7GFJ8, BIOD_CLOBL ;  B1KW07, BIOD_CLOBM ;
DR   B9E076, BIOD_CLOK1 ;  A5N6Q7, BIOD_CLOK5 ;  A0PYU7, BIOD_CLONN ;
DR   Q0TQ60, BIOD_CLOP1 ;  Q8XK60, BIOD_CLOPE ;  Q893G4, BIOD_CLOTE ;
DR   Q6NHE6, BIOD_CORDI ;  Q8FPS0, BIOD_COREF ;  A4QH04, BIOD_CORGB ;
DR   P46397, BIOD_CORGL ;  C4LIG1, BIOD_CORK4 ;  B1WZW5, BIOD_CYAA5 ;
DR   B8HNL6, BIOD_CYAP4 ;  B7KBS1, BIOD_CYAP7 ;  B7K5E6, BIOD_CYAP8 ;
DR   Q11QU6, BIOD_CYTH3 ;  O06899, BIOD_ESCVU ;  B0U0S6, BIOD_FRAP2 ;
DR   Q2J6H9, BIOD_FRASC ;  A8L2N1, BIOD_FRASN ;  Q14HR7, BIOD_FRAT1 ;
DR   A7NCX0, BIOD_FRATF ;  Q2A2V6, BIOD_FRATH ;  B2SGE0, BIOD_FRATM ;
DR   A0Q635, BIOD_FRATN ;  Q0BLD2, BIOD_FRATO ;  Q5NGB5, BIOD_FRATT ;
DR   A4IXP2, BIOD_FRATW ;  Q8RET9, BIOD_FUSNN ;  Q5KVI4, BIOD_GEOKA ;
DR   C5D7L1, BIOD_GEOSW ;  Q7NFL5, BIOD_GLOVI ;  A0M7A5, BIOD_GRAFK ;
DR   Q9ZN34, BIOD_HELPJ ;  B2UW31, BIOD_HELPS ;  O24872, BIOD_HELPY ;
DR   B4U7U3, BIOD_HYDS0 ;  Q5QZ19, BIOD_IDILO ;  A6SU65, BIOD_JANMA ;
DR   Q1MR97, BIOD_LAWIP ;  Q5X589, BIOD_LEGPA ;  A5IBW5, BIOD_LEGPC ;
DR   Q5ZVG5, BIOD_LEGPH ;  Q5WWA0, BIOD_LEGPL ;  Q04RS7, BIOD_LEPBJ ;
DR   Q051U4, BIOD_LEPBL ;  Q72RG6, BIOD_LEPIC ;  Q8F4A0, BIOD_LEPIN ;
DR   B1HRT5, BIOD_LYSSC ;  P22818, BIOD_LYSSH ;  Q2W3K9, BIOD_MAGSA ;
DR   Q65TU7, BIOD_MANSM ;  A1U4A9, BIOD_MARAV ;  A6UVE3, BIOD_META3 ;
DR   Q58695, BIOD_METJA ;  B8IBW1, BIOD_METNO ;  A6UQL8, BIOD_METVS ;
DR   B0JX07, BIOD_MICAN ;  A0QHJ8, BIOD_MYCA1 ;  B1MBZ5, BIOD_MYCA9 ;
DR   O52587, BIOD_MYCBO ;  A1KJ01, BIOD_MYCBP ;  C1ANK7, BIOD_MYCBT ;
DR   A4T9L2, BIOD_MYCGI ;  B8ZR85, BIOD_MYCLB ;  P45486, BIOD_MYCLE ;
DR   B2HQ91, BIOD_MYCMM ;  A0QX66, BIOD_MYCS2 ;  A3Q145, BIOD_MYCSJ ;
DR   A1UHM2, BIOD_MYCSK ;  Q1B7F1, BIOD_MYCSS ;  A5U2S7, BIOD_MYCTA ;
DR   O06620, BIOD_MYCTU ;  A0PP03, BIOD_MYCUA ;  A1T8U7, BIOD_MYCVP ;
DR   Q5F9T1, BIOD_NEIG1 ;  B4RJZ8, BIOD_NEIG2 ;  A9M388, BIOD_NEIM0 ;
DR   Q9JV95, BIOD_NEIMA ;  Q9K085, BIOD_NEIMB ;  A1KSZ5, BIOD_NEIMF ;
DR   Q2GDE9, BIOD_NEOSM ;  Q1QJL1, BIOD_NITHX ;  A9A5K8, BIOD_NITMS ;
DR   Q2Y9Y5, BIOD_NITMU ;  Q3SPW7, BIOD_NITWN ;  Q5YYS5, BIOD_NOCFA ;
DR   Q2GAF9, BIOD_NOVAD ;  A6X2S6, BIOD_OCHA4 ;  B6JGN8, BIOD_OLICO ;
DR   B4RFX6, BIOD_PHEZH ;  Q6LPR5, BIOD_PHOPR ;  A6UYW4, BIOD_PSEA7 ;
DR   B7V489, BIOD_PSEA8 ;  Q02TR2, BIOD_PSEAB ;  Q9I614, BIOD_PSEAE ;
DR   Q3IGS9, BIOD_PSEHT ;  B2UBJ4, BIOD_RALPJ ;  Q8XZC2, BIOD_RALSO ;
DR   Q7URG0, BIOD_RHOBA ;  C1A0S6, BIOD_RHOE4 ;  Q2IRY0, BIOD_RHOP2 ;
DR   Q07L51, BIOD_RHOP5 ;  Q6N5K3, BIOD_RHOPA ;  Q216N4, BIOD_RHOPB ;
DR   Q130N3, BIOD_RHOPS ;  B3Q7Q5, BIOD_RHOPT ;  Q0SHV6, BIOD_RHOSR ;
DR   A1AV54, BIOD_RUTMC ;  A4F8D5, BIOD_SACEN ;  P36572, BIOD_SERMA ;
DR   Q1GT35, BIOD_SPHAL ;  A5V5Q4, BIOD_SPHWW ;  Q5HKF0, BIOD_STAEQ ;
DR   Q8CQD8, BIOD_STAES ;  Q826T4, BIOD_STRAW ;  Q9FCC1, BIOD_STRCO ;
DR   A6QBZ9, BIOD_SULNB ;  Q55849, BIOD_SYNY3 ;  B5YHS9, BIOD_THEYD ;
DR   C4LDD0, BIOD_TOLAT ;  B1H0L0, BIOD_UNCTG ;  A5CY11, BIOD_VESOH ;
DR   Q9KSZ1, BIOD_VIBCH ;  Q5DZI1, BIOD_VIBF1 ;  B5EUP7, BIOD_VIBFM ;
DR   A7MX33, BIOD_VIBHB ;  Q87QN3, BIOD_VIBPA ;  Q8D8N2, BIOD_VIBVU ;
DR   Q7MLU7, BIOD_VIBVY ;  Q8D298, BIOD_WIGBR ;  Q7MAC6, BIOD_WOLSU ;
DR   Q8PGK0, BIOD_XANAC ;  Q3BP46, BIOD_XANC5 ;  Q4UQI6, BIOD_XANC8 ;
DR   B0RVN9, BIOD_XANCB ;  Q8PCW4, BIOD_XANCP ;  Q2P7M5, BIOD_XANOM ;
DR   B2SQ77, BIOD_XANOP ;  Q9PAL9, BIOD_XYLFA ;  B0U3W7, BIOD_XYLFM ;
DR   Q87BG0, BIOD_XYLFT ;  P53630, BIOD_YEAST ;  A9R3D1, BIOD_YERPG ;
DR   P69954, BIOD_YERPS ;
//
ID   6.3.3.4
DE   (Carboxyethyl)arginine beta-lactam-synthase.
AN   Beta-lactam synthetase.
CA   ATP + L-N(2)-(2-carboxyethyl)arginine = AMP + diphosphate +
CA   deoxyamidinoproclavaminate.
CC   -!- Forms part of the pathway for the biosythesis of the beta-lactamase
CC       inhibitor clavulanate in Streptomyces clavuligerus.
CC   -!- It has been proposed that L-N(2)-(2-carboxyethyl)arginine is first
CC       converted into an acyl-AMP by reaction with ATP and loss of
CC       diphosphate, and that the beta-lactam ring is then formed by the
CC       intramolecular attack of the beta-nitrogen on the activated carboxy
CC       group.
DR   Q9R8E3, BLS_STRCL  ;
//
ID   6.3.4.1
DE   GMP synthase.
AN   Xanthosine-5'-phosphate--ammonia ligase.
AN   XMP aminase.
CA   ATP + xanthosine 5'-phosphate + NH(3) = AMP + diphosphate + GMP.
//
ID   6.3.4.2
DE   CTP synthase.
AN   CTP synthetase.
AN   UTP--ammonia ligase.
CA   ATP + UTP + NH(3) = ADP + phosphate + CTP.
CC   -!- Glutamine can replace NH(3).
PR   PROSITE; PDOC00405;
DR   Q5XHA8, PYG1A_XENLA;  Q7ZXP9, PYG1B_XENLA;  P50547, PYRG1_CRIGR;
DR   Q6PEI7, PYRG1_DANRE;  P17812, PYRG1_HUMAN;  P70698, PYRG1_MOUSE;
DR   Q1RMS2, PYRG2_BOVIN;  Q5F3Z1, PYRG2_CHICK;  Q9NRF8, PYRG2_HUMAN;
DR   P70303, PYRG2_MOUSE;  Q5U2N0, PYRG2_RAT  ;  Q6GME1, PYRG2_XENLA;
DR   B0CBC7, PYRG_ACAM1 ;  A1TLT0, PYRG_ACIAC ;  Q6FAT7, PYRG_ACIAD ;
DR   B7H225, PYRG_ACIB3 ;  B7I920, PYRG_ACIB5 ;  B2I2A7, PYRG_ACIBC ;
DR   Q1IKC9, PYRG_ACIBL ;  B0VQI6, PYRG_ACIBS ;  A3M5Y3, PYRG_ACIBT ;
DR   B0V675, PYRG_ACIBY ;  A0LUA5, PYRG_ACIC1 ;  C1F1E7, PYRG_ACIC5 ;
DR   A5FXW7, PYRG_ACICJ ;  B9MEQ7, PYRG_ACIET ;  B7J6R2, PYRG_ACIF2 ;
DR   B5EPM5, PYRG_ACIF5 ;  A1W4R3, PYRG_ACISJ ;  A3MYK8, PYRG_ACTP2 ;
DR   B3GZX8, PYRG_ACTP7 ;  B0BS41, PYRG_ACTPJ ;  A6VR01, PYRG_ACTSZ ;
DR   A0KGH2, PYRG_AERHH ;  Q9YBJ4, PYRG_AERPE ;  A4SRC2, PYRG_AERS4 ;
DR   Q8UEY5, PYRG_AGRT5 ;  Q0VQD8, PYRG_ALCBS ;  Q0A7K2, PYRG_ALHEH ;
DR   B6EKL9, PYRG_ALISL ;  B4RVU4, PYRG_ALTMD ;  B8JBN6, PYRG_ANAD2 ;
DR   Q2IH81, PYRG_ANADE ;  A7HIF0, PYRG_ANADF ;  B9KHF1, PYRG_ANAMF ;
DR   Q5PBX6, PYRG_ANAMM ;  Q2GLS9, PYRG_ANAPZ ;  B4UIT6, PYRG_ANASK ;
DR   Q3MAV1, PYRG_ANAVT ;  O67353, PYRG_AQUAE ;  O29987, PYRG_ARCFU ;
DR   Q5NZ71, PYRG_AROAE ;  Q751L7, PYRG_ASHGO ;  Q2NK04, PYRG_AYWBP ;
DR   P28595, PYRG_AZOBR ;  A1K7F8, PYRG_AZOSB ;  C1DSS8, PYRG_AZOVD ;
DR   A7Z9T4, PYRG_BACA2 ;  C3P2A0, PYRG_BACAA ;  C3LFL2, PYRG_BACAC ;
DR   A0RLC3, PYRG_BACAH ;  Q81JW1, PYRG_BACAN ;  B7JHG1, PYRG_BACC0 ;
DR   Q72XB0, PYRG_BACC1 ;  B7IQZ1, PYRG_BACC2 ;  C1F0R6, PYRG_BACC3 ;
DR   B7HFN6, PYRG_BACC4 ;  B7HY98, PYRG_BACC7 ;  A7GV88, PYRG_BACCN ;
DR   B9IRX1, PYRG_BACCQ ;  Q814T2, PYRG_BACCR ;  Q630R0, PYRG_BACCZ ;
DR   Q5LC42, PYRG_BACFN ;  Q64T27, PYRG_BACFR ;  Q9K6D7, PYRG_BACHD ;
DR   Q6HAU5, PYRG_BACHK ;  Q65DT7, PYRG_BACLD ;  A8FIE5, PYRG_BACP2 ;
DR   Q5WB43, PYRG_BACSK ;  P13242, PYRG_BACSU ;  Q8AA75, PYRG_BACTN ;
DR   A9VSD6, PYRG_BACWK ;  A1US92, PYRG_BARBK ;  Q6G410, PYRG_BARHE ;
DR   Q6G027, PYRG_BARQU ;  A9IS43, PYRG_BART1 ;  Q1LTN7, PYRG_BAUCH ;
DR   Q6MPP0, PYRG_BDEBA ;  B2IKQ2, PYRG_BEII9 ;  Q8G5X7, PYRG_BIFLO ;
DR   Q7VQH4, PYRG_BLOFL ;  Q493N6, PYRG_BLOPB ;  Q2KZF8, PYRG_BORA1 ;
DR   Q0SMT3, PYRG_BORAP ;  Q7WD72, PYRG_BORBR ;  O51522, PYRG_BORBU ;
DR   Q660U9, PYRG_BORGA ;  Q7W5N6, PYRG_BORPA ;  A9IIP5, PYRG_BORPD ;
DR   Q7VW76, PYRG_BORPE ;  Q89KU5, PYRG_BRAJA ;  A5EK18, PYRG_BRASB ;
DR   A4YVC9, PYRG_BRASO ;  B2S5Y5, PYRG_BRUA1 ;  Q2YPU8, PYRG_BRUA2 ;
DR   Q57D05, PYRG_BRUAB ;  A9M5E7, PYRG_BRUC2 ;  C0RJA5, PYRG_BRUMB ;
DR   Q8YHF2, PYRG_BRUME ;  A5VQQ9, PYRG_BRUO2 ;  B0CGT4, PYRG_BRUSI ;
DR   Q8G0G1, PYRG_BRUSU ;  B8D9J4, PYRG_BUCA5 ;  P57491, PYRG_BUCAI ;
DR   P59039, PYRG_BUCAP ;  B8D7U6, PYRG_BUCAT ;  P59577, PYRG_BUCBP ;
DR   B1YT11, PYRG_BURA4 ;  Q1BHS2, PYRG_BURCA ;  B1JUY8, PYRG_BURCC ;
DR   A0K8N3, PYRG_BURCH ;  B4EDA3, PYRG_BURCJ ;  Q0BDS1, PYRG_BURCM ;
DR   A9AGW0, PYRG_BURM1 ;  A3ML79, PYRG_BURM7 ;  A2SAU5, PYRG_BURM9 ;
DR   Q62J08, PYRG_BURMA ;  A1V5K4, PYRG_BURMS ;  Q3JQQ4, PYRG_BURP1 ;
DR   B2JIX2, PYRG_BURP8 ;  B2SXV1, PYRG_BURPP ;  Q63SP8, PYRG_BURPS ;
DR   Q39EV7, PYRG_BURS3 ;  Q2SXC7, PYRG_BURTA ;  A4JFY7, PYRG_BURVG ;
DR   Q13X05, PYRG_BURXL ;  A8MB89, PYRG_CALMQ ;  A8FJJ0, PYRG_CAMJ8 ;
DR   A7H1B7, PYRG_CAMJD ;  Q9PJ84, PYRG_CAMJE ;  A1VXA6, PYRG_CAMJJ ;
DR   Q5HXD1, PYRG_CAMJR ;  Q6FUD0, PYRG_CANGA ;  Q3AFT7, PYRG_CARHZ ;
DR   B8GW64, PYRG_CAUCN ;  Q9A7K3, PYRG_CAUCR ;  B0SYY1, PYRG_CAUSK ;
DR   A9WJ75, PYRG_CHLAA ;  Q5L5S1, PYRG_CHLAB ;  B8GAQ5, PYRG_CHLAD ;
DR   Q3ANY4, PYRG_CHLCH ;  Q822T2, PYRG_CHLCV ;  Q254V9, PYRG_CHLFF ;
DR   B3EE77, PYRG_CHLL2 ;  Q9PKL0, PYRG_CHLMU ;  B3QRL0, PYRG_CHLP8 ;
DR   B3EK39, PYRG_CHLPB ;  A1BJR8, PYRG_CHLPD ;  Q9Z8U8, PYRG_CHLPN ;
DR   B9LB79, PYRG_CHLSY ;  B0B9T3, PYRG_CHLT2 ;  B3QWC0, PYRG_CHLT3 ;
DR   Q3KMH9, PYRG_CHLTA ;  B0BBG3, PYRG_CHLTB ;  P59040, PYRG_CHLTE ;
DR   Q59321, PYRG_CHLTR ;  Q1QZX9, PYRG_CHRSD ;  Q7NSG9, PYRG_CHRVO ;
DR   A8ANY8, PYRG_CITK8 ;  Q97F61, PYRG_CLOAB ;  A6LQF6, PYRG_CLOB8 ;
DR   B8I598, PYRG_CLOCE ;  A5N3K4, PYRG_CLOK5 ;  Q0TNA4, PYRG_CLOP1 ;
DR   Q8XIB3, PYRG_CLOPE ;  Q0SQX5, PYRG_CLOPS ;  A3DGR3, PYRG_CLOTH ;
DR   Q47WQ9, PYRG_COLP3 ;  B5Y8A3, PYRG_COPPD ;  Q8FTL2, PYRG_COREF ;
DR   A4QE10, PYRG_CORGB ;  Q8NQL7, PYRG_CORGL ;  Q4JVX2, PYRG_CORJK ;
DR   C4LIF4, PYRG_CORK4 ;  B6J4W8, PYRG_COXB1 ;  B6J3W7, PYRG_COXB2 ;
DR   A9KDH0, PYRG_COXBN ;  A9N9V5, PYRG_COXBR ;  Q83B36, PYRG_COXBU ;
DR   Q0KCE5, PYRG_CUPNH ;  Q473G7, PYRG_CUPPJ ;  B3R496, PYRG_CUPTR ;
DR   B1WV74, PYRG_CYAA5 ;  B8HNM9, PYRG_CYAP4 ;  B7KF08, PYRG_CYAP7 ;
DR   B7JVR6, PYRG_CYAP8 ;  Q11S24, PYRG_CYTH3 ;  Q47DH9, PYRG_DECAR ;
DR   Q3Z6N1, PYRG_DEHE1 ;  A5FPS8, PYRG_DEHSB ;  Q3ZYU1, PYRG_DEHSC ;
DR   C1CWM4, PYRG_DEIDV ;  Q1J055, PYRG_DEIGD ;  Q9RU23, PYRG_DEIRA ;
DR   A9BN39, PYRG_DELAS ;  C6BWN7, PYRG_DESAD ;  B8IZF5, PYRG_DESDA ;
DR   Q310T4, PYRG_DESDG ;  Q24MK9, PYRG_DESHY ;  Q6AQ78, PYRG_DESPS ;
DR   Q72BL2, PYRG_DESVH ;  B8DJR8, PYRG_DESVM ;  A1VDL2, PYRG_DESVV ;
DR   Q54V77, PYRG_DICDI ;  A5EW22, PYRG_DICNV ;  A8LIN6, PYRG_DINSH ;
DR   Q9VUL1, PYRG_DROME ;  Q2M197, PYRG_DROPS ;  A7ZQM3, PYRG_ECO24 ;
DR   B7UHJ6, PYRG_ECO27 ;  B7MLA1, PYRG_ECO45 ;  B7LEK0, PYRG_ECO55 ;
DR   P0A7E7, PYRG_ECO57 ;  B5Z3E4, PYRG_ECO5E ;  B7NV70, PYRG_ECO7I ;
DR   B7MZ76, PYRG_ECO81 ;  B7LXJ6, PYRG_ECO8A ;  C4ZZT3, PYRG_ECOBW ;
DR   B1XDJ0, PYRG_ECODH ;  A8A3R5, PYRG_ECOHS ;  A1AEW8, PYRG_ECOK1 ;
DR   Q0TE79, PYRG_ECOL5 ;  P0A7E6, PYRG_ECOL6 ;  B1IU61, PYRG_ECOLC ;
DR   P0A7E5, PYRG_ECOLI ;  B7N716, PYRG_ECOLU ;  B6I6H6, PYRG_ECOSE ;
DR   B1LQB3, PYRG_ECOSM ;  Q1R7R3, PYRG_ECOUT ;  C5B8X3, PYRG_EDWI9 ;
DR   Q3YSZ0, PYRG_EHRCJ ;  Q2GHT7, PYRG_EHRCR ;  Q5FFC3, PYRG_EHRRG ;
DR   Q5HC60, PYRG_EHRRW ;  Q8SQI7, PYRG_ENCCU ;  A4WDW8, PYRG_ENT38 ;
DR   Q836G5, PYRG_ENTFA ;  A7MQY9, PYRG_ENTS8 ;  Q6D181, PYRG_ERWCT ;
DR   B2VFY9, PYRG_ERWT9 ;  Q2NAA7, PYRG_ERYLH ;  B7LWP4, PYRG_ESCF3 ;
DR   Q939R0, PYRG_FIBSS ;  A5FHA4, PYRG_FLAJ1 ;  A6H0U1, PYRG_FLAPJ ;
DR   B0U0L7, PYRG_FRAP2 ;  Q2J878, PYRG_FRASC ;  Q14J73, PYRG_FRAT1 ;
DR   A7ND08, PYRG_FRATF ;  Q2A2S0, PYRG_FRATH ;  B2SFK1, PYRG_FRATM ;
DR   A0Q4L3, PYRG_FRATN ;  Q0BLA3, PYRG_FRATO ;  Q5NHS1, PYRG_FRATT ;
DR   A4IZP3, PYRG_FRATW ;  Q5KUG2, PYRG_GEOKA ;  B3EAK5, PYRG_GEOLS ;
DR   Q39W62, PYRG_GEOMG ;  B9M9Q5, PYRG_GEOSF ;  Q74BY3, PYRG_GEOSL ;
DR   A5G5T3, PYRG_GEOUR ;  O74638, PYRG_GIBZE ;  Q7NKF4, PYRG_GLOVI ;
DR   A9HJ81, PYRG_GLUDA ;  Q5FNN2, PYRG_GLUOX ;  Q0BTX6, PYRG_GRABC ;
DR   A0M3I8, PYRG_GRAFK ;  Q7VNV5, PYRG_HAEDU ;  Q4QLL2, PYRG_HAEI8 ;
DR   A5UD28, PYRG_HAEIE ;  A5UIK2, PYRG_HAEIG ;  P44341, PYRG_HAEIN ;
DR   B8F5Q9, PYRG_HAEPS ;  Q0I200, PYRG_HAES1 ;  Q2SKX2, PYRG_HAHCH ;
DR   A1WWZ4, PYRG_HALHL ;  Q5UX57, PYRG_HALMA ;  B0R6G2, PYRG_HALS3 ;
DR   Q9HP32, PYRG_HALSA ;  Q18FG3, PYRG_HALWD ;  C4K4K0, PYRG_HAMD5 ;
DR   Q7VGH1, PYRG_HELHP ;  Q1CUG1, PYRG_HELPH ;  Q9ZM99, PYRG_HELPJ ;
DR   O25116, PYRG_HELPY ;  A9B6S7, PYRG_HERA2 ;  A4G738, PYRG_HERAR ;
DR   B4U6A9, PYRG_HYDS0 ;  Q0C195, PYRG_HYPNA ;  Q5R142, PYRG_IDILO ;
DR   A6SXG2, PYRG_JANMA ;  Q28MG4, PYRG_JANSC ;  B5XV18, PYRG_KLEP3 ;
DR   A6TD54, PYRG_KLEP7 ;  Q5FME6, PYRG_LACAC ;  Q03T27, PYRG_LACBA ;
DR   Q1GBQ2, PYRG_LACDA ;  Q04C51, PYRG_LACDB ;  A8YXF8, PYRG_LACH4 ;
DR   Q74LG2, PYRG_LACJO ;  Q9CI75, PYRG_LACLA ;  O87761, PYRG_LACLM ;
DR   Q88Z76, PYRG_LACPL ;  Q1WV30, PYRG_LACS1 ;  Q38V48, PYRG_LACSS ;
DR   C1DCC1, PYRG_LARHH ;  Q1MR71, PYRG_LAWIP ;  Q5X5Y6, PYRG_LEGPA ;
DR   A5IB79, PYRG_LEGPC ;  Q5ZWA4, PYRG_LEGPH ;  Q5WXA8, PYRG_LEGPL ;
DR   Q6AGG5, PYRG_LEIXX ;  B1Y4K6, PYRG_LEPCP ;  Q72S46, PYRG_LEPIC ;
DR   Q8F3J3, PYRG_LEPIN ;  Q927T4, PYRG_LISIN ;  Q71WM0, PYRG_LISMF ;
DR   Q8Y495, PYRG_LISMO ;  Q2W6A0, PYRG_MAGSA ;  Q65VZ8, PYRG_MANSM ;
DR   A1TZ46, PYRG_MARAV ;  Q0APT7, PYRG_MARMM ;  Q6F0G9, PYRG_MESFL ;
DR   Q11HU6, PYRG_MESSB ;  A6UTE4, PYRG_META3 ;  Q8TKW5, PYRG_METAC ;
DR   A7IA93, PYRG_METB6 ;  Q465Q4, PYRG_METBF ;  Q12WH5, PYRG_METBU ;
DR   B7KUU9, PYRG_METC4 ;  Q604M6, PYRG_METCA ;  Q1H009, PYRG_METFK ;
DR   Q2FSE6, PYRG_METHJ ;  Q58574, PYRG_METJA ;  Q8TYT7, PYRG_METKA ;
DR   A2SSJ7, PYRG_METLZ ;  Q8Q0L8, PYRG_METMA ;  A3CWS5, PYRG_METMJ ;
DR   Q6LYU4, PYRG_METMP ;  B8IP92, PYRG_METNO ;  B1Z9R0, PYRG_METPB ;
DR   B8GIB3, PYRG_METPE ;  B1M5Q9, PYRG_METRJ ;  B0U802, PYRG_METS4 ;
DR   B8EJS8, PYRG_METSB ;  Q2NH50, PYRG_METST ;  O26519, PYRG_METTH ;
DR   A0B7H6, PYRG_METTP ;  B0JU82, PYRG_MICAN ;  Q2RFU8, PYRG_MOOTA ;
DR   A0QH68, PYRG_MYCA1 ;  P0A5U3, PYRG_MYCBO ;  A1KJB5, PYRG_MYCBP ;
DR   C1ANX1, PYRG_MYCBT ;  Q93DW6, PYRG_MYCCC ;  Q48965, PYRG_MYCCT ;
DR   A4T9Y6, PYRG_MYCGI ;  B8ZRH6, PYRG_MYCLB ;  P53529, PYRG_MYCLE ;
DR   B2HR69, PYRG_MYCMM ;  Q6MUA3, PYRG_MYCMS ;  Q740E5, PYRG_MYCPA ;
DR   Q98PQ3, PYRG_MYCPU ;  A0QYQ7, PYRG_MYCS2 ;  A3Q0R1, PYRG_MYCSJ ;
DR   A1UH74, PYRG_MYCSK ;  Q1B7T3, PYRG_MYCSS ;  A5U357, PYRG_MYCTA ;
DR   P0A5U2, PYRG_MYCTU ;  A0PPA8, PYRG_MYCUA ;  A1TA81, PYRG_MYCVP ;
DR   Q1DDB7, PYRG_MYXXD ;  Q3IS15, PYRG_NATPD ;  B2A3K5, PYRG_NATTJ ;
DR   B9L7R9, PYRG_NAUPA ;  Q5F7G6, PYRG_NEIG1 ;  B4RJ40, PYRG_NEIG2 ;
DR   A9M0Y3, PYRG_NEIM0 ;  Q9JTK1, PYRG_NEIMA ;  Q9JYJ8, PYRG_NEIMB ;
DR   A1KUX8, PYRG_NEIMF ;  Q2GCQ2, PYRG_NEOSM ;  Q7RZV2, PYRG_NEUCR ;
DR   Q0AD92, PYRG_NITEC ;  O85347, PYRG_NITEU ;  Q1QMJ4, PYRG_NITHX ;
DR   Q2Y9P1, PYRG_NITMU ;  Q3JCT3, PYRG_NITOC ;  Q3SRJ8, PYRG_NITWN ;
DR   Q5YY90, PYRG_NOCFA ;  A1SJK4, PYRG_NOCSJ ;  B2IUT0, PYRG_NOSP7 ;
DR   Q8YMD4, PYRG_NOSS1 ;  Q2G6R7, PYRG_NOVAD ;  Q8EM53, PYRG_OCEIH ;
DR   A6X0L6, PYRG_OCHA4 ;  Q6YPW4, PYRG_ONYPE ;  A1B8D4, PYRG_PARDP ;
DR   A7HXX9, PYRG_PARL1 ;  Q6MD01, PYRG_PARUW ;  Q9CJW9, PYRG_PASMU ;
DR   C6DDJ6, PYRG_PECCP ;  Q3A371, PYRG_PELCD ;  Q3B6P1, PYRG_PELLD ;
DR   B4SAT4, PYRG_PELPB ;  A1APF9, PYRG_PELPD ;  A5CYA0, PYRG_PELTS ;
DR   Q4FM39, PYRG_PELUB ;  B4RBW5, PYRG_PHEZH ;  Q7N836, PYRG_PHOLL ;
DR   Q6LMT0, PYRG_PHOPR ;  B1VAI9, PYRG_PHYAS ;  Q6L1K7, PYRG_PICTO ;
DR   A1VLH3, PYRG_POLNA ;  B1XUS0, PYRG_POLNS ;  Q128E7, PYRG_POLSJ ;
DR   A4SXE7, PYRG_POLSQ ;  B2RKS1, PYRG_PORG3 ;  Q7MWR7, PYRG_PORGI ;
DR   B4S3A5, PYRG_PROA2 ;  Q6A7X4, PYRG_PROAC ;  A3PFH8, PYRG_PROM0 ;
DR   A2C5F9, PYRG_PROM1 ;  A8G7J4, PYRG_PROM2 ;  A2CDX8, PYRG_PROM3 ;
DR   A9BDD9, PYRG_PROM4 ;  A2BZ76, PYRG_PROM5 ;  Q317V2, PYRG_PROM9 ;
DR   Q7V9I0, PYRG_PROMA ;  B4EUF6, PYRG_PROMH ;  Q7V3W8, PYRG_PROMM ;
DR   Q7UZH7, PYRG_PROMP ;  A2BTS1, PYRG_PROMS ;  Q46I97, PYRG_PROMT ;
DR   A4SCI7, PYRG_PROVI ;  Q48F77, PYRG_PSE14 ;  Q15QR7, PYRG_PSEA6 ;
DR   A6V1F1, PYRG_PSEA7 ;  B7V7V1, PYRG_PSEA8 ;  Q02RA9, PYRG_PSEAB ;
DR   Q9HXZ4, PYRG_PSEAE ;  Q1I644, PYRG_PSEE4 ;  Q4KHF8, PYRG_PSEF5 ;
DR   C3K6H4, PYRG_PSEFS ;  Q3IDM3, PYRG_PSEHT ;  A4XWS3, PYRG_PSEMY ;
DR   A5W831, PYRG_PSEP1 ;  Q3KH94, PYRG_PSEPF ;  B0KSB7, PYRG_PSEPG ;
DR   Q88MG1, PYRG_PSEPK ;  B1JBP2, PYRG_PSEPW ;  Q886M5, PYRG_PSESM ;
DR   Q4ZWR0, PYRG_PSEU2 ;  A4VJT9, PYRG_PSEU5 ;  Q4FR69, PYRG_PSYA2 ;
DR   Q1Q9K1, PYRG_PSYCK ;  A1SSQ6, PYRG_PSYIN ;  A5WG19, PYRG_PSYWF ;
DR   Q9V1S2, PYRG_PYRAB ;  Q8ZSY7, PYRG_PYRAE ;  A3MXN2, PYRG_PYRCJ ;
DR   Q8TZY6, PYRG_PYRFU ;  O59456, PYRG_PYRHO ;  Q5JGF1, PYRG_PYRKO ;
DR   Q1LPI8, PYRG_RALME ;  B2U9C0, PYRG_RALPJ ;  Q8Y0B8, PYRG_RALSO ;
DR   B3Q0M2, PYRG_RHIE6 ;  Q2K871, PYRG_RHIEC ;  Q1MGC4, PYRG_RHIL3 ;
DR   Q98MF0, PYRG_RHILO ;  B5ZPZ7, PYRG_RHILW ;  Q92QA0, PYRG_RHIME ;
DR   Q7UJ86, PYRG_RHOBA ;  B6IQ27, PYRG_RHOCS ;  Q21V39, PYRG_RHOFD ;
DR   C1ASX9, PYRG_RHOOB ;  Q2IWB8, PYRG_RHOP2 ;  Q07NF1, PYRG_RHOP5 ;
DR   Q6N5T4, PYRG_RHOPA ;  Q215B2, PYRG_RHOPB ;  Q136D7, PYRG_RHOPS ;
DR   B3Q6M4, PYRG_RHOPT ;  Q2RT58, PYRG_RHORT ;  A3PLA0, PYRG_RHOS1 ;
DR   Q3J0Z1, PYRG_RHOS4 ;  A4WQW2, PYRG_RHOS5 ;  B9KKB0, PYRG_RHOSK ;
DR   Q0SI74, PYRG_RHOSR ;  Q1RHU4, PYRG_RICBR ;  Q92I97, PYRG_RICCN ;
DR   Q4ULX9, PYRG_RICFE ;  Q9ZDF1, PYRG_RICPR ;  C4K2E0, PYRG_RICPU ;
DR   B0BXB3, PYRG_RICRO ;  A8GRV6, PYRG_RICRS ;  Q68WZ6, PYRG_RICTY ;
DR   A7NN90, PYRG_ROSCS ;  Q168S7, PYRG_ROSDO ;  A5UXX5, PYRG_ROSS1 ;
DR   Q1AW18, PYRG_RUBXD ;  Q21LC4, PYRG_SACD2 ;  A4FKA9, PYRG_SACEN ;
DR   B5F4P0, PYRG_SALA4 ;  A9MF10, PYRG_SALAR ;  Q57KG9, PYRG_SALCH ;
DR   B5FTV0, PYRG_SALDC ;  B5QW41, PYRG_SALEP ;  B5RDS6, PYRG_SALG2 ;
DR   B4TFZ2, PYRG_SALHS ;  B4T484, PYRG_SALNS ;  Q5PEJ0, PYRG_SALPA ;
DR   A9N2F5, PYRG_SALPB ;  C0PXD6, PYRG_SALPC ;  B5BF03, PYRG_SALPK ;
DR   Q2S538, PYRG_SALRD ;  B4TTY6, PYRG_SALSV ;  P65922, PYRG_SALTI ;
DR   P65921, PYRG_SALTY ;  O42644, PYRG_SCHPO ;  A8G9W0, PYRG_SERP5 ;
DR   A1S4D6, PYRG_SHEAM ;  B8E8T0, PYRG_SHEB2 ;  A3D796, PYRG_SHEB5 ;
DR   A6WR29, PYRG_SHEB8 ;  A9KYH1, PYRG_SHEB9 ;  Q12PZ5, PYRG_SHEDO ;
DR   Q086B1, PYRG_SHEFN ;  B0TK03, PYRG_SHEHH ;  A3QC76, PYRG_SHELP ;
DR   Q8EBQ9, PYRG_SHEON ;  A8H1S4, PYRG_SHEPA ;  A4Y944, PYRG_SHEPC ;
DR   A0KU81, PYRG_SHESA ;  A8FSS7, PYRG_SHESH ;  Q0HL73, PYRG_SHESM ;
DR   Q0HXH1, PYRG_SHESR ;  A1RHF2, PYRG_SHESW ;  B1KPT7, PYRG_SHEWM ;
DR   B2TZF3, PYRG_SHIB3 ;  Q31XL0, PYRG_SHIBS ;  Q32CD5, PYRG_SHIDS ;
DR   Q0T1P8, PYRG_SHIF8 ;  P0A7E8, PYRG_SHIFL ;  Q3YY76, PYRG_SHISS ;
DR   Q5LTV0, PYRG_SILPO ;  Q1GF61, PYRG_SILST ;  A6U8E2, PYRG_SINMW ;
DR   Q2NVN8, PYRG_SODGM ;  Q1GTY6, PYRG_SPHAL ;  A5V8U1, PYRG_SPHWW ;
DR   P52200, PYRG_SPICI ;  A7X4X7, PYRG_STAA1 ;  A6U3L2, PYRG_STAA2 ;
DR   Q2FF01, PYRG_STAA3 ;  Q2FWD1, PYRG_STAA8 ;  A5IUS2, PYRG_STAA9 ;
DR   Q2YUM6, PYRG_STAAB ;  Q5HE73, PYRG_STAAC ;  A6QIX1, PYRG_STAAE ;
DR   P65923, PYRG_STAAM ;  P99072, PYRG_STAAN ;  Q6GEU8, PYRG_STAAR ;
DR   Q6G7I3, PYRG_STAAS ;  A8YY92, PYRG_STAAT ;  P65924, PYRG_STAAW ;
DR   B9DME0, PYRG_STACT ;  Q5HM95, PYRG_STAEQ ;  Q8CNI2, PYRG_STAES ;
DR   Q4L808, PYRG_STAHJ ;  Q49Z73, PYRG_STAS1 ;  Q3K3S2, PYRG_STRA1 ;
DR   Q8E7P8, PYRG_STRA3 ;  Q8E290, PYRG_STRA5 ;  Q829A7, PYRG_STRAW ;
DR   Q9S224, PYRG_STRCO ;  C0M8K6, PYRG_STRE4 ;  A8AZ08, PYRG_STRGC ;
DR   B1W203, PYRG_STRGG ;  B4SR82, PYRG_STRM5 ;  B2FK84, PYRG_STRMK ;
DR   Q8DWG1, PYRG_STRMU ;  P65925, PYRG_STRP1 ;  P0DD70, PYRG_STRP3 ;
DR   Q5XA10, PYRG_STRP6 ;  Q8NZF8, PYRG_STRP8 ;  Q1J9X6, PYRG_STRPB ;
DR   Q1JK23, PYRG_STRPC ;  Q1JF16, PYRG_STRPD ;  Q1J4X1, PYRG_STRPF ;
DR   Q48RF1, PYRG_STRPM ;  Q97S93, PYRG_STRPN ;  P0DD71, PYRG_STRPQ ;
DR   Q8DQY0, PYRG_STRR6 ;  C0MFQ9, PYRG_STRS7 ;  A3CQB0, PYRG_STRSV ;
DR   Q5M1S7, PYRG_STRT1 ;  Q5M6C0, PYRG_STRT2 ;  Q4JAK8, PYRG_SULAC ;
DR   Q30NS7, PYRG_SULDN ;  Q980S6, PYRG_SULSO ;  Q976E9, PYRG_SULTO ;
DR   Q67TG8, PYRG_SYMTH ;  Q2LRK2, PYRG_SYNAS ;  Q54775, PYRG_SYNE7 ;
DR   Q2JUH1, PYRG_SYNJA ;  Q2JLG7, PYRG_SYNJB ;  B1XMC5, PYRG_SYNP2 ;
DR   Q5N040, PYRG_SYNP6 ;  A5GPM2, PYRG_SYNPW ;  Q7U3K4, PYRG_SYNPX ;
DR   A5GWT6, PYRG_SYNR3 ;  Q0I677, PYRG_SYNS3 ;  Q3AUG4, PYRG_SYNS9 ;
DR   Q3AGF7, PYRG_SYNSC ;  Q0AU97, PYRG_SYNWW ;  P74208, PYRG_SYNY3 ;
DR   B7IH88, PYRG_THEAB ;  Q9HM27, PYRG_THEAC ;  Q8DKT7, PYRG_THEEB ;
DR   Q47QN2, PYRG_THEFY ;  C5A7F1, PYRG_THEGJ ;  Q9WZR0, PYRG_THEMA ;
DR   B6YTF0, PYRG_THEON ;  B9L1H7, PYRG_THERP ;  Q72IN0, PYRG_THET2 ;
DR   Q5SIA8, PYRG_THET8 ;  Q8R720, PYRG_THETN ;  Q97CR8, PYRG_THEVO ;
DR   Q31G66, PYRG_THICR ;  Q3SL45, PYRG_THIDA ;  B8GQ73, PYRG_THISH ;
DR   C4LBR2, PYRG_TOLAT ;  Q73J84, PYRG_TREDE ;  O83327, PYRG_TREPA ;
DR   B2S2Q3, PYRG_TREPS ;  Q110M9, PYRG_TRIEI ;  Q83IC4, PYRG_TROW8 ;
DR   Q83GX8, PYRG_TROWT ;  Q9PQK7, PYRG_UREPA ;  C5CSV3, PYRG_VARPS ;
DR   A1WL89, PYRG_VEREI ;  A5F5I4, PYRG_VIBC3 ;  Q9KPC4, PYRG_VIBCH ;
DR   C3LQZ1, PYRG_VIBCM ;  Q5E325, PYRG_VIBF1 ;  B5FAG0, PYRG_VIBFM ;
DR   A7MTS6, PYRG_VIBHB ;  Q87LP9, PYRG_VIBPA ;  B7VK69, PYRG_VIBSL ;
DR   Q8DC63, PYRG_VIBVU ;  Q7MHQ0, PYRG_VIBVY ;  Q8D2K0, PYRG_WIGBR ;
DR   Q73HS5, PYRG_WOLPM ;  Q7MAI3, PYRG_WOLSU ;  Q5GTB4, PYRG_WOLTR ;
DR   Q8PLS3, PYRG_XANAC ;  Q3BUT3, PYRG_XANC5 ;  Q4UTN9, PYRG_XANC8 ;
DR   B0RUK3, PYRG_XANCB ;  Q8P9Z6, PYRG_XANCP ;  Q2P1K5, PYRG_XANOM ;
DR   B2SUA3, PYRG_XANOP ;  Q5GYK0, PYRG_XANOR ;  B2I935, PYRG_XYLF2 ;
DR   Q9PDU1, PYRG_XYLFA ;  B0U656, PYRG_XYLFM ;  Q87DY8, PYRG_XYLFT ;
DR   A1JJR3, PYRG_YERE8 ;  A7FLZ6, PYRG_YERP3 ;  Q1C3Y5, PYRG_YERPA ;
DR   B2K560, PYRG_YERPB ;  Q8ZBN1, PYRG_YERPE ;  A9R1D2, PYRG_YERPG ;
DR   Q1CLT3, PYRG_YERPN ;  A4TPY0, PYRG_YERPP ;  Q66ED9, PYRG_YERPS ;
DR   B1JK10, PYRG_YERPY ;  Q5NQB9, PYRG_ZYMMO ;  P28274, URA7_YEAST ;
DR   A6ZQ59, URA8_YEAS7 ;  P38627, URA8_YEAST ;
//
ID   6.3.4.3
DE   Formate--tetrahydrofolate ligase.
AN   Formyltetrahydrofolate synthetase.
AN   Tetrahydrofolate formylase.
AN   Tetrahydrofolic formylase.
CA   ATP + formate + tetrahydrofolate = ADP + phosphate +
CA   10-formyltetrahydrofolate.
CC   -!- In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5
CC       and EC 3.5.4.9 activity.
PR   PROSITE; PDOC00595;
DR   O96553, C1TC_DROME ;  P11586, C1TC_HUMAN ;  Q922D8, C1TC_MOUSE ;
DR   Q5R8P0, C1TC_PONAB ;  P27653, C1TC_RAT   ;  Q8WZJ7, C1TC_SCHPO ;
DR   Q27772, C1TC_SPOFR ;  P07245, C1TC_YEAST ;  Q0VCR7, C1TM_BOVIN ;
DR   Q6UB35, C1TM_HUMAN ;  Q3V3R1, C1TM_MOUSE ;  O43007, C1TM_SCHPO ;
DR   P09440, C1TM_YEAST ;  Q251P8, FTHS1_DESHY;  Q5FJY2, FTHS1_LACAC;
DR   Q1AXZ4, FTHS1_RUBXD;  Q99ZI9, FTHS1_STRP1;  P0DF90, FTHS1_STRP3;
DR   Q5XC12, FTHS1_STRP6;  Q8P0X5, FTHS1_STRP8;  Q1JBM0, FTHS1_STRPB;
DR   Q1JLK2, FTHS1_STRPC;  Q1JGN8, FTHS1_STRPD;  Q1J6F7, FTHS1_STRPF;
DR   A2REC4, FTHS1_STRPG;  Q48TE8, FTHS1_STRPM;  P0DF91, FTHS1_STRPQ;
DR   A3CL27, FTHS1_STRSV;  Q24ZZ8, FTHS2_DESHY;  Q5FIU5, FTHS2_LACAC;
DR   Q1AVP8, FTHS2_RUBXD;  Q99XR2, FTHS2_STRP1;  P0DF92, FTHS2_STRP3;
DR   Q5X9K7, FTHS2_STRP6;  Q8NZ49, FTHS2_STRP8;  Q1J9F2, FTHS2_STRPB;
DR   Q1JJK1, FTHS2_STRPC;  Q1JEK4, FTHS2_STRPD;  Q1J4C0, FTHS2_STRPF;
DR   A2RGS2, FTHS2_STRPG;  Q48QZ2, FTHS2_STRPM;  P0DF93, FTHS2_STRPQ;
DR   A3CN49, FTHS2_STRSV;  Q1AT39, FTHS3_RUBXD;  A9NE95, FTHS_ACHLI ;
DR   A5G276, FTHS_ACICJ ;  A3MZI4, FTHS_ACTP2 ;  B3GX43, FTHS_ACTP7 ;
DR   A0KIN9, FTHS_AERHH ;  A4SPE5, FTHS_AERS4 ;  B9J7E8, FTHS_AGRRK ;
DR   B9JZN5, FTHS_AGRVS ;  B6EIJ9, FTHS_ALISL ;  A8MIN1, FTHS_ALKOO ;
DR   B9MM59, FTHS_ANATD ;  Q9SPK5, FTHS_ARATH ;  A1R8N9, FTHS_ARTAT ;
DR   A0JZ10, FTHS_ARTS2 ;  C3P858, FTHS_BACAA ;  C3LKJ6, FTHS_BACAC ;
DR   A0RD97, FTHS_BACAH ;  Q81RE1, FTHS_BACAN ;  B7JLG8, FTHS_BACC0 ;
DR   Q739F4, FTHS_BACC1 ;  B7IUA4, FTHS_BACC2 ;  C1ES77, FTHS_BACC3 ;
DR   B7HP29, FTHS_BACC7 ;  B9IYP4, FTHS_BACCQ ;  Q81E87, FTHS_BACCR ;
DR   Q63C61, FTHS_BACCZ ;  Q5LD60, FTHS_BACFN ;  Q64U80, FTHS_BACFR ;
DR   Q6HJK9, FTHS_BACHK ;  Q65IA6, FTHS_BACLD ;  A8FEC9, FTHS_BACP2 ;
DR   Q8A9S8, FTHS_BACTN ;  A6L4P0, FTHS_BACV8 ;  A9IM41, FTHS_BART1 ;
DR   B2IC30, FTHS_BEII9 ;  Q8G700, FTHS_BIFLO ;  C0QX38, FTHS_BRAHW ;
DR   A4XIU2, FTHS_CALS8 ;  A8Z6G1, FTHS_CAMC1 ;  A7GZZ0, FTHS_CAMC5 ;
DR   Q3A9K2, FTHS_CARHZ ;  A9WIW3, FTHS_CHLAA ;  B8GC03, FTHS_CHLAD ;
DR   B9LKW0, FTHS_CHLSY ;  Q97EB3, FTHS_CLOAB ;  P13419, FTHS_CLOAC ;
DR   A7FZB0, FTHS_CLOB1 ;  C3KVU4, FTHS_CLOB6 ;  A6LPL1, FTHS_CLOB8 ;
DR   B2UXU5, FTHS_CLOBA ;  B2TI29, FTHS_CLOBB ;  A5I7P9, FTHS_CLOBH ;
DR   C1FND0, FTHS_CLOBJ ;  B1IGY1, FTHS_CLOBK ;  A7GJB8, FTHS_CLOBL ;
DR   B1KTC6, FTHS_CLOBM ;  B8I3S9, FTHS_CLOCE ;  Q07064, FTHS_CLOCY ;
DR   Q189R2, FTHS_CLOD6 ;  B9DYW1, FTHS_CLOK1 ;  A5N5B3, FTHS_CLOK5 ;
DR   A0PXN0, FTHS_CLONN ;  Q0TMI3, FTHS_CLOP1 ;  Q8XHL4, FTHS_CLOPE ;
DR   A9KNJ5, FTHS_CLOPH ;  Q0SQ82, FTHS_CLOPS ;  Q891R3, FTHS_CLOTE ;
DR   A3DI22, FTHS_CLOTH ;  Q6NH87, FTHS_CORDI ;  Q4JVW2, FTHS_CORJK ;
DR   Q3Z8K3, FTHS_DEHE1 ;  Q3ZX40, FTHS_DEHSC ;  B8FGU7, FTHS_DESAA ;
DR   C0QAX9, FTHS_DESAH ;  B8J0C2, FTHS_DESDA ;  A8ZZJ0, FTHS_DESOH ;
DR   Q6AL19, FTHS_DESPS ;  A4J0S6, FTHS_DESRM ;  A8LIR1, FTHS_DINSH ;
DR   B2KDK9, FTHS_ELUMP ;  Q834D6, FTHS_ENTFA ;  Q5XZD9, FTHS_EUBAC ;
DR   C4Z1V6, FTHS_EUBE2 ;  C4ZBG8, FTHS_EUBR3 ;  A7HLZ4, FTHS_FERNB ;
DR   B0S0G1, FTHS_FINM2 ;  Q8RHF4, FTHS_FUSNN ;  Q0BW57, FTHS_GRABC ;
DR   Q7VLW6, FTHS_HAEDU ;  Q5V5Y2, FTHS_HALMA ;  B8D067, FTHS_HALOH ;
DR   Q18JB5, FTHS_HALWD ;  B0TBP1, FTHS_HELMI ;  A9B4H8, FTHS_HERA2 ;
DR   Q0BX04, FTHS_HYPNA ;  Q28TR4, FTHS_JANSC ;  C5CI89, FTHS_KOSOT ;
DR   Q03S45, FTHS_LACBA ;  Q038Y4, FTHS_LACC3 ;  B3WEG3, FTHS_LACCB ;
DR   Q1GA94, FTHS_LACDA ;  Q04AM0, FTHS_LACDB ;  B2GF64, FTHS_LACF3 ;
DR   Q043I0, FTHS_LACGA ;  Q74JC1, FTHS_LACJO ;  Q9CH07, FTHS_LACLA ;
DR   A2RLK1, FTHS_LACLM ;  Q02ZS7, FTHS_LACLS ;  Q88W76, FTHS_LACPL ;
DR   A5VHS9, FTHS_LACRD ;  B2G5A9, FTHS_LACRJ ;  Q1WTW0, FTHS_LACS1 ;
DR   Q38X32, FTHS_LACSS ;  Q1MPZ9, FTHS_LAWIP ;  B1MY45, FTHS_LEUCK ;
DR   Q03YB1, FTHS_LEUMM ;  Q92AD2, FTHS_LISIN ;  C1KWH6, FTHS_LISMC ;
DR   Q71YD9, FTHS_LISMF ;  B8DDM6, FTHS_LISMH ;  Q8Y624, FTHS_LISMO ;
DR   A0AJY2, FTHS_LISW6 ;  Q0APT3, FTHS_MARMM ;  Q11G79, FTHS_MESSB ;
DR   B7L0A5, FTHS_METC4 ;  Q605Q9, FTHS_METCA ;  Q83WS0, FTHS_METEA ;
DR   A9VZT0, FTHS_METEP ;  Q1GZ16, FTHS_METFK ;  A2SS72, FTHS_METLZ ;
DR   B8IBS4, FTHS_METNO ;  B1ZJ88, FTHS_METPB ;  A2SKX8, FTHS_METPP ;
DR   B1M0D1, FTHS_METRJ ;  B0UQF5, FTHS_METS4 ;  B8EKB9, FTHS_METSB ;
DR   Q2RM91, FTHS_MOOTA ;  P21164, FTHS_MOOTH ;  Q8EUQ1, FTHS_MYCPE ;
DR   Q1DFW5, FTHS_MYXXD ;  B2A3Q6, FTHS_NATTJ ;  Q5FAG1, FTHS_NEIG1 ;
DR   B4RP08, FTHS_NEIG2 ;  A9M1J1, FTHS_NEIM0 ;  Q9JVY8, FTHS_NEIMA ;
DR   Q9JXY2, FTHS_NEIMB ;  A1KS57, FTHS_NEIMF ;  A1SQH3, FTHS_NOCSJ ;
DR   Q04FS6, FTHS_OENOB ;  A6LAR6, FTHS_PARD8 ;  A1B1M8, FTHS_PARDP ;
DR   Q03FM6, FTHS_PEDPA ;  Q4FL49, FTHS_PELUB ;  A9BIV8, FTHS_PETMO ;
DR   Q6LNJ0, FTHS_PHOPR ;  Q6KZM3, FTHS_PICTO ;  Q7MUZ8, FTHS_PORGI ;
DR   Q6ABS5, FTHS_PROAC ;  B4ET09, FTHS_PROMH ;  O66164, FTHS_PSEPA ;
DR   A5WI04, FTHS_PSYWF ;  A9WMW3, FTHS_RENSM ;  B3PV59, FTHS_RHIE6 ;
DR   Q2K5P2, FTHS_RHIEC ;  Q1MDG4, FTHS_RHIL3 ;  Q98HQ4, FTHS_RHILO ;
DR   B5ZYA2, FTHS_RHILW ;  Q92N42, FTHS_RHIME ;  C3MFQ8, FTHS_RHISN ;
DR   A3PM52, FTHS_RHOS1 ;  Q3J047, FTHS_RHOS4 ;  A4WQ11, FTHS_RHOS5 ;
DR   B9KLK4, FTHS_RHOSK ;  A7NGQ9, FTHS_ROSCS ;  Q160C2, FTHS_ROSDO ;
DR   A5UPV2, FTHS_ROSS1 ;  A4FL80, FTHS_SACEN ;  A1SAE2, FTHS_SHEAM ;
DR   B8ECE1, FTHS_SHEB2 ;  A3CZY6, FTHS_SHEB5 ;  A6WSY9, FTHS_SHEB8 ;
DR   A9L3Z6, FTHS_SHEB9 ;  B0TVP3, FTHS_SHEHH ;  A3QA17, FTHS_SHELP ;
DR   Q8EJA7, FTHS_SHEON ;  A8H8Z4, FTHS_SHEPA ;  A4YAP3, FTHS_SHEPC ;
DR   B8CI99, FTHS_SHEPW ;  A0KSN0, FTHS_SHESA ;  A8FQV1, FTHS_SHESH ;
DR   Q0HMS6, FTHS_SHESM ;  Q0HR05, FTHS_SHESR ;  A1RFN3, FTHS_SHESW ;
DR   B1KJC0, FTHS_SHEWM ;  Q5LNV0, FTHS_SILPO ;  Q1GE26, FTHS_SILST ;
DR   A6UBV0, FTHS_SINMW ;  P28723, FTHS_SPIOL ;  A7X3G5, FTHS_STAA1 ;
DR   A6U2J8, FTHS_STAA2 ;  Q2FG06, FTHS_STAA3 ;  Q2G296, FTHS_STAA8 ;
DR   A5ITQ4, FTHS_STAA9 ;  Q2YTF6, FTHS_STAAB ;  Q5HF42, FTHS_STAAC ;
DR   A6QHR5, FTHS_STAAE ;  Q99TD2, FTHS_STAAM ;  Q7A535, FTHS_STAAN ;
DR   Q6GFX6, FTHS_STAAR ;  Q6G8J5, FTHS_STAAS ;  A8Z2Q0, FTHS_STAAT ;
DR   Q8NW37, FTHS_STAAW ;  B9DN77, FTHS_STACT ;  Q5HNH4, FTHS_STAEQ ;
DR   Q8CNV9, FTHS_STAES ;  Q4L776, FTHS_STAHJ ;  Q3K138, FTHS_STRA1 ;
DR   Q8E5E3, FTHS_STRA3 ;  Q8DZP5, FTHS_STRA5 ;  C0M9N3, FTHS_STRE4 ;
DR   B4U2T6, FTHS_STREM ;  Q59925, FTHS_STRMU ;  Q04K90, FTHS_STRP2 ;
DR   B5E4W4, FTHS_STRP4 ;  C1C7J4, FTHS_STRP7 ;  B1IC26, FTHS_STRPI ;
DR   B8ZJQ0, FTHS_STRPJ ;  Q97QI2, FTHS_STRPN ;  B2IPQ3, FTHS_STRPS ;
DR   Q8DPL5, FTHS_STRR6 ;  A4W0G0, FTHS_STRS2 ;  C0MFU5, FTHS_STRS7 ;
DR   A4VU67, FTHS_STRSY ;  Q5M083, FTHS_STRT1 ;  Q5M4U2, FTHS_STRT2 ;
DR   Q03L41, FTHS_STRTD ;  B9DS83, FTHS_STRU0 ;  C1CEI6, FTHS_STRZJ ;
DR   C1CKW9, FTHS_STRZP ;  C1CR74, FTHS_STRZT ;  Q67JH9, FTHS_SYMTH ;
DR   Q2LU82, FTHS_SYNAS ;  A0LLR3, FTHS_SYNFM ;  Q0AX38, FTHS_SYNWW ;
DR   B7IG29, FTHS_THEAB ;  Q9HI67, FTHS_THEAC ;  A8F7D5, FTHS_THELT ;
DR   A6LJS5, FTHS_THEM4 ;  Q9X287, FTHS_THEMA ;  A5ILJ8, FTHS_THEP1 ;
DR   B0KC36, FTHS_THEP3 ;  B0K5A5, FTHS_THEPX ;  B1LAQ7, FTHS_THESQ ;
DR   Q72GY9, FTHS_THET2 ;  Q8R7L3, FTHS_THETN ;  Q97CL3, FTHS_THEVO ;
DR   B5YJE1, FTHS_THEYD ;  Q73RR6, FTHS_TREDE ;  Q9PQS1, FTHS_UREPA ;
DR   Q9KLX7, FTHS_VIBCH ;  Q5E3V8, FTHS_VIBF1 ;  B5FG96, FTHS_VIBFM ;
DR   A7N5E9, FTHS_VIBHB ;  Q87HX2, FTHS_VIBPA ;  B7VSJ2, FTHS_VIBSL ;
DR   Q8D7D8, FTHS_VIBVU ;  Q7MEE8, FTHS_VIBVY ;  A1JMA3, FTHS_YERE8 ;
DR   Q5NQC7, FTHS_ZYMMO ;
//
ID   6.3.4.4
DE   Adenylosuccinate synthase.
AN   Adenylosuccinate synthetase.
AN   IMP--aspartate ligase.
AN   Succinoadenylic kinosynthetase.
CA   GTP + IMP + L-aspartate = GDP + phosphate + N(6)-(1,2-dicarboxyethyl)-
CA   AMP.
PR   PROSITE; PDOC00444;
DR   B5X2Z0, PUA1A_SALSA;  Q561L1, PUA1A_XENLA;  B5DGM3, PUA1B_SALSA;
DR   Q68F20, PUA1B_XENLA;  B5DGM4, PUA1C_SALSA;  Q6P875, PUA2A_XENTR;
DR   Q28GB0, PUA2B_XENTR;  A5PJR4, PURA1_BOVIN;  Q39FS0, PURA1_BURS3;
DR   A9XLE1, PURA1_CAPFR;  Q7P071, PURA1_CHRVO;  Q46ZJ3, PURA1_CUPPJ;
DR   Q6NSN5, PURA1_DANRE;  Q8N142, PURA1_HUMAN;  B0DQB9, PURA1_LACBS;
DR   Q8TPJ2, PURA1_METAC;  P28650, PURA1_MOUSE;  Q10R17, PURA1_ORYSJ;
DR   Q7N8D4, PURA1_PHOLL;  A9SCV9, PURA1_PHYPA;  A4Z6H0, PURA1_PIG  ;
DR   Q3IEZ3, PURA1_PSEHT;  B9TAD0, PURA1_RICCO;  C5WVW2, PURA1_SORBI;
DR   Q4DLT6, PURA1_TRYCR;  Q6DIW6, PURA1_XENTR;  A7MBG0, PURA2_BOVIN;
DR   Q39PN9, PURA2_BURS3;  A9XLE2, PURA2_CAPFR;  Q5ZJL5, PURA2_CHICK;
DR   Q7NS98, PURA2_CHRVO;  Q46QQ8, PURA2_CUPPJ;  Q568F6, PURA2_DANRE;
DR   P30520, PURA2_HUMAN;  B0DUI8, PURA2_LACBS;  Q8TIM8, PURA2_METAC;
DR   P46664, PURA2_MOUSE;  Q851S8, PURA2_ORYSJ;  Q7MAX9, PURA2_PHOLL;
DR   A9TIK2, PURA2_PHYPA;  A4Z6H1, PURA2_PIG  ;  Q3IIQ6, PURA2_PSEHT;
DR   B9SL58, PURA2_RICCO;  C5WNV2, PURA2_SORBI;  Q4CWX1, PURA2_TRYCR;
DR   Q7ZY87, PURA2_XENLA;  B0CBU2, PURA_ACAM1 ;  A1TM37, PURA_ACIAC ;
DR   Q6FCS7, PURA_ACIAD ;  Q1IJT2, PURA_ACIBL ;  A0LWT8, PURA_ACIC1 ;
DR   A5G293, PURA_ACICJ ;  B9MFY7, PURA_ACIET ;  A1W588, PURA_ACISJ ;
DR   A3N181, PURA_ACTP2 ;  B3H1V8, PURA_ACTP7 ;  B0BQ12, PURA_ACTPJ ;
DR   A6VQD4, PURA_ACTSZ ;  Q17G75, PURA_AEDAE ;  P96771, PURA_AGGAC ;
DR   B9J8Q9, PURA_AGRRK ;  Q8UCN6, PURA_AGRT5 ;  B9JRD7, PURA_AGRVS ;
DR   C0NL18, PURA_AJECG ;  C6HBB1, PURA_AJECH ;  A6R8V2, PURA_AJECN ;
DR   C5GA45, PURA_AJEDR ;  C5JKJ6, PURA_AJEDS ;  Q0VMF3, PURA_ALCBS ;
DR   Q0AB55, PURA_ALHEH ;  A6TXB3, PURA_ALKMQ ;  B4S195, PURA_ALTMD ;
DR   B8JDH9, PURA_ANAD2 ;  Q2IQF7, PURA_ANADE ;  A7HDA9, PURA_ANADF ;
DR   Q5PAA8, PURA_ANAMM ;  B4UGW9, PURA_ANASK ;  B9MLK0, PURA_ANATD ;
DR   Q3MBG1, PURA_ANAVT ;  O67321, PURA_AQUAE ;  Q96529, PURA_ARATH ;
DR   A8ER43, PURA_ARCB4 ;  O29417, PURA_ARCFU ;  Q5P7C4, PURA_AROAE ;
DR   A1R2A8, PURA_ARTAT ;  B8HBV4, PURA_ARTCA ;  C5FC83, PURA_ARTOC ;
DR   A0JSA1, PURA_ARTS2 ;  Q75E56, PURA_ASHGO ;  A1CNR3, PURA_ASPCL ;
DR   B0XNF8, PURA_ASPFC ;  B8MZA3, PURA_ASPFN ;  Q4WRQ7, PURA_ASPFU ;
DR   A2QB52, PURA_ASPNC ;  Q2UQQ2, PURA_ASPOR ;  Q0CM45, PURA_ASPTN ;
DR   A8I1V7, PURA_AZOC5 ;  B6YR45, PURA_AZOPC ;  A1K400, PURA_AZOSB ;
DR   C1DLQ8, PURA_AZOVD ;  A7AU38, PURA_BABBO ;  A7ZAP4, PURA_BACA2 ;
DR   A0RLP6, PURA_BACAH ;  Q81JI9, PURA_BACAN ;  Q72WW1, PURA_BACC1 ;
DR   A7GVN0, PURA_BACCN ;  Q814H1, PURA_BACCR ;  Q630D5, PURA_BACCZ ;
DR   Q5LAD5, PURA_BACFN ;  Q64QR7, PURA_BACFR ;  Q9K5R0, PURA_BACHD ;
DR   Q6HAG9, PURA_BACHK ;  Q65CR5, PURA_BACLD ;  A8FJC0, PURA_BACP2 ;
DR   Q5WAI0, PURA_BACSK ;  P29726, PURA_BACSU ;  Q8A6N4, PURA_BACTN ;
DR   A6L1X1, PURA_BACV8 ;  A1URK5, PURA_BARBK ;  Q6G4G5, PURA_BARHE ;
DR   Q6G1A4, PURA_BARQU ;  A9IQ57, PURA_BART1 ;  Q1LSQ9, PURA_BAUCH ;
DR   Q6MN06, PURA_BDEBA ;  B2ICM9, PURA_BEII9 ;  C5C333, PURA_BEUC1 ;
DR   B8DVC2, PURA_BIFA0 ;  A0ZZG5, PURA_BIFAA ;  B3DNT3, PURA_BIFLD ;
DR   Q8G6T9, PURA_BIFLO ;  B7GT29, PURA_BIFLS ;  Q7VQP1, PURA_BLOFL ;
DR   Q494F3, PURA_BLOPB ;  Q2KYA7, PURA_BORA1 ;  Q7WHP1, PURA_BORBR ;
DR   B5RLY1, PURA_BORDL ;  Q7W6Q7, PURA_BORPA ;  A9IK82, PURA_BORPD ;
DR   Q7VWM1, PURA_BORPE ;  B5RRM9, PURA_BORRA ;  A1QZK9, PURA_BORT9 ;
DR   C0R2E2, PURA_BRAHW ;  Q89EM1, PURA_BRAJA ;  A5ED09, PURA_BRASB ;
DR   A4Z0B8, PURA_BRASO ;  C0ZA40, PURA_BREBN ;  Q2YQI5, PURA_BRUA2 ;
DR   P0C115, PURA_BRUAB ;  A9M7I3, PURA_BRUC2 ;  A8QE42, PURA_BRUMA ;
DR   C0REU7, PURA_BRUMB ;  P65878, PURA_BRUME ;  A5VS40, PURA_BRUO2 ;
DR   A9WWG0, PURA_BRUSI ;  P65879, PURA_BRUSU ;  B8D8D0, PURA_BUCA5 ;
DR   P57629, PURA_BUCAI ;  Q8K916, PURA_BUCAP ;  B8D887, PURA_BUCAT ;
DR   P59428, PURA_BUCBP ;  A3MK63, PURA_BURM7 ;  A2S2B3, PURA_BURM9 ;
DR   Q62JX6, PURA_BURMA ;  A1V4I9, PURA_BURMS ;  A3NVV9, PURA_BURP0 ;
DR   Q3JRR4, PURA_BURP1 ;  A3NA42, PURA_BURP6 ;  B2JIU0, PURA_BURP8 ;
DR   B2SXR9, PURA_BURPP ;  Q63US2, PURA_BURPS ;  Q2SWD3, PURA_BURTA ;
DR   Q13X40, PURA_BURXL ;  A8X7H5, PURA_CAEBR ;  P91134, PURA_CAEEL ;
DR   A4XML6, PURA_CALS8 ;  A7ZFJ4, PURA_CAMC1 ;  A7H0A8, PURA_CAMC5 ;
DR   A0RMY9, PURA_CAMFF ;  A7I328, PURA_CAMHC ;  A8FNG4, PURA_CAMJ8 ;
DR   A7H5L7, PURA_CAMJD ;  Q9PMG4, PURA_CAMJE ;  A1W1A5, PURA_CAMJJ ;
DR   Q5HST3, PURA_CAMJR ;  B9KF91, PURA_CAMLR ;  P0CH96, PURA_CANAL ;
DR   P0CH97, PURA_CANAW ;  B9W8Y2, PURA_CANDC ;  Q6FMU9, PURA_CANGA ;
DR   C5MBF2, PURA_CANTT ;  Q3A8S5, PURA_CARHZ ;  B8H3C9, PURA_CAUCN ;
DR   Q9A3U9, PURA_CAUCR ;  B0T890, PURA_CAUSK ;  Q2H9E8, PURA_CHAGB ;
DR   Q3APK8, PURA_CHLCH ;  B3EGV7, PURA_CHLL2 ;  B3QQZ0, PURA_CHLP8 ;
DR   A1BJ01, PURA_CHLPD ;  A8IW34, PURA_CHLRE ;  Q8KAK6, PURA_CHLTE ;
DR   Q1QY21, PURA_CHRSD ;  A8AMM3, PURA_CITK8 ;  Q97D87, PURA_CLOAB ;
DR   A7FZF9, PURA_CLOB1 ;  C3KWG8, PURA_CLOB6 ;  A6M3K0, PURA_CLOB8 ;
DR   B2V1S6, PURA_CLOBA ;  B2TRE4, PURA_CLOBB ;  A5I7Y9, PURA_CLOBH ;
DR   C1FNL8, PURA_CLOBJ ;  B1IHP2, PURA_CLOBK ;  A7GJL2, PURA_CLOBL ;
DR   B1KU85, PURA_CLOBM ;  B8I5L3, PURA_CLOCE ;  Q181Q7, PURA_CLOD6 ;
DR   A5N4D3, PURA_CLOK5 ;  A0PXA8, PURA_CLONN ;  Q8XH63, PURA_CLOPE ;
DR   A3DK09, PURA_CLOTH ;  C5PAD0, PURA_COCP7 ;  Q48A17, PURA_COLP3 ;
DR   A8NDT2, PURA_COPC7 ;  C3PJK0, PURA_CORA7 ;  Q9RHX5, PURA_CORAM ;
DR   Q6NF38, PURA_CORDI ;  Q8FMB0, PURA_COREF ;  A4QHG2, PURA_CORGB ;
DR   Q8NM16, PURA_CORGL ;  Q4JXT3, PURA_CORJK ;  B1VHT9, PURA_CORU7 ;
DR   B6J734, PURA_COXB1 ;  B6J083, PURA_COXB2 ;  A9KCC7, PURA_COXBN ;
DR   A9NCS8, PURA_COXBR ;  Q83CV4, PURA_COXBU ;  P0CQ35, PURA_CRYNB ;
DR   P0CQ34, PURA_CRYNJ ;  B0W9B4, PURA_CULQU ;  B1WSJ0, PURA_CYAA5 ;
DR   B8HY86, PURA_CYAP4 ;  B7KCX9, PURA_CYAP7 ;  B7JXN4, PURA_CYAP8 ;
DR   Q11UE6, PURA_CYTH3 ;  Q6BUG5, PURA_DEBHA ;  Q47BS7, PURA_DECAR ;
DR   Q3Z7V0, PURA_DEHE1 ;  A5FQS4, PURA_DEHSB ;  Q3ZXV0, PURA_DEHSC ;
DR   C1CZ40, PURA_DEIDV ;  Q1J1X6, PURA_DEIGD ;  Q9RYB5, PURA_DEIRA ;
DR   A9BMU3, PURA_DELAS ;  B8FB83, PURA_DESAA ;  C6BRT2, PURA_DESAD ;
DR   C0QB49, PURA_DESAH ;  B1I6P8, PURA_DESAP ;  B8J4N1, PURA_DESDA ;
DR   Q317B9, PURA_DESDG ;  B8G0I5, PURA_DESHD ;  Q24MC6, PURA_DESHY ;
DR   A8ZTF0, PURA_DESOH ;  Q6AN65, PURA_DESPS ;  A4J9P7, PURA_DESRM ;
DR   Q725K9, PURA_DESVH ;  B8DQ18, PURA_DESVM ;  A1V9U1, PURA_DESVV ;
DR   P21900, PURA_DICDI ;  A5EVE1, PURA_DICNV ;  A8LIN4, PURA_DINSH ;
DR   B3M343, PURA_DROAN ;  B3P321, PURA_DROER ;  B4JUE4, PURA_DROGR ;
DR   Q9Y0Y2, PURA_DROME ;  B4K8W7, PURA_DROMO ;  B4G518, PURA_DROPE ;
DR   Q299D3, PURA_DROPS ;  B4II68, PURA_DROSE ;  B4LWK0, PURA_DROVI ;
DR   B4NFS5, PURA_DROWI ;  B4PPT4, PURA_DROYA ;  A7ZV47, PURA_ECO24 ;
DR   B7UQI6, PURA_ECO27 ;  B7MKY1, PURA_ECO45 ;  B7LC36, PURA_ECO55 ;
DR   P0A7D6, PURA_ECO57 ;  B5Z2I3, PURA_ECO5E ;  B7NTN3, PURA_ECO7I ;
DR   B7MSJ5, PURA_ECO81 ;  B7M8T7, PURA_ECO8A ;  C4ZR54, PURA_ECOBW ;
DR   B1XDS8, PURA_ECODH ;  A8A7S2, PURA_ECOHS ;  A1AJ82, PURA_ECOK1 ;
DR   Q0T9L6, PURA_ECOL5 ;  P0A7D5, PURA_ECOL6 ;  B1IT29, PURA_ECOLC ;
DR   P0A7D4, PURA_ECOLI ;  B7NGB1, PURA_ECOLU ;  B6I281, PURA_ECOSE ;
DR   B1LQJ7, PURA_ECOSM ;  Q1R383, PURA_ECOUT ;  O31047, PURA_EDWI9 ;
DR   Q3YRQ6, PURA_EHRCJ ;  Q2GH05, PURA_EHRCR ;  Q5FFQ3, PURA_EHRRG ;
DR   Q5HAW8, PURA_EHRRW ;  Q5BEY7, PURA_EMENI ;  A4W5R8, PURA_ENT38 ;
DR   Q839Y4, PURA_ENTFA ;  A7MM94, PURA_ENTS8 ;  Q6D072, PURA_ERWCT ;
DR   B2VCW8, PURA_ERWT9 ;  Q2NCV0, PURA_ERYLH ;  B7LLV9, PURA_ESCF3 ;
DR   B1YG93, PURA_EXIS2 ;  C4L014, PURA_EXISA ;  A7HMJ8, PURA_FERNB ;
DR   B0RZL3, PURA_FINM2 ;  A5FHR3, PURA_FLAJ1 ;  A6H0U4, PURA_FLAPJ ;
DR   Q0RBA3, PURA_FRAAA ;  B0TVV8, PURA_FRAP2 ;  Q2J4S8, PURA_FRASC ;
DR   A8LDR3, PURA_FRASN ;  Q14JN1, PURA_FRAT1 ;  A7NEW1, PURA_FRATF ;
DR   Q2A167, PURA_FRATH ;  B2SE78, PURA_FRATM ;  A0Q4C3, PURA_FRATN ;
DR   Q0BJY9, PURA_FRATO ;  Q5NI78, PURA_FRATT ;  A4J037, PURA_FRATW ;
DR   P58793, PURA_FUSNN ;  O68581, PURA_FUSNU ;  B5ECF3, PURA_GEOBB ;
DR   Q5KU76, PURA_GEOKA ;  B3EAS4, PURA_GEOLS ;  Q39QK1, PURA_GEOMG ;
DR   B9M1R2, PURA_GEOSF ;  Q747F9, PURA_GEOSL ;  C6DZQ7, PURA_GEOSM ;
DR   C5D9W9, PURA_GEOSW ;  A4ITU9, PURA_GEOTN ;  A5GC19, PURA_GEOUR ;
DR   Q7NG93, PURA_GLOVI ;  A9HLQ1, PURA_GLUDA ;  Q5FQZ9, PURA_GLUOX ;
DR   Q0BTV7, PURA_GRABC ;  A0LZF7, PURA_GRAFK ;  Q7VKR5, PURA_HAEDU ;
DR   Q4QL68, PURA_HAEI8 ;  A5UCM6, PURA_HAEIE ;  A5UIZ2, PURA_HAEIG ;
DR   P45283, PURA_HAEIN ;  B8F8E6, PURA_HAEPS ;  Q0I4Q5, PURA_HAES1 ;
DR   B0UW92, PURA_HAES2 ;  Q2SBC8, PURA_HAHCH ;  A1WUT0, PURA_HALHL ;
DR   Q5V2N1, PURA_HALMA ;  B8D1A3, PURA_HALOH ;  B0R4U8, PURA_HALS3 ;
DR   Q9HQM6, PURA_HALSA ;  C4K3C2, PURA_HAMD5 ;  Q17W85, PURA_HELAH ;
DR   Q7VHL2, PURA_HELHP ;  B0TA52, PURA_HELMI ;  B6JKI4, PURA_HELP2 ;
DR   B5ZA21, PURA_HELPG ;  Q1CUP8, PURA_HELPH ;  Q9ZMI1, PURA_HELPJ ;
DR   B2US87, PURA_HELPS ;  P56137, PURA_HELPY ;  A4G4L2, PURA_HERAR ;
DR   B4U9K9, PURA_HYDS0 ;  Q0BXJ3, PURA_HYPNA ;  Q5QW95, PURA_IDILO ;
DR   Q28MG6, PURA_JANSC ;  A6WFJ3, PURA_KINRD ;  B5Y325, PURA_KLEP3 ;
DR   A6TH93, PURA_KLEP7 ;  Q6CQ65, PURA_KLULA ;  B2GL12, PURA_KOCRD ;
DR   Q5FHY4, PURA_LACAC ;  Q03TS9, PURA_LACBA ;  Q03CT6, PURA_LACC3 ;
DR   B3W7G1, PURA_LACCB ;  Q1GBV4, PURA_LACDA ;  B2GEZ1, PURA_LACF3 ;
DR   Q045S7, PURA_LACGA ;  A8YTK4, PURA_LACH4 ;  Q74KY3, PURA_LACJO ;
DR   Q9CE93, PURA_LACLA ;  A2RN80, PURA_LACLM ;  Q02WK8, PURA_LACLS ;
DR   Q88SV6, PURA_LACPL ;  A5VHM0, PURA_LACRD ;  B2G550, PURA_LACRJ ;
DR   Q1WRH2, PURA_LACS1 ;  Q38ZL5, PURA_LACSS ;  C5DD42, PURA_LACTC ;
DR   Q1MRW8, PURA_LAWIP ;  Q5X7Q5, PURA_LEGPA ;  A5IHA9, PURA_LEGPC ;
DR   Q5ZY86, PURA_LEGPH ;  Q5WZ56, PURA_LEGPL ;  Q8RNM2, PURA_LEGPN ;
DR   A4H7A3, PURA_LEIBR ;  A7LBL2, PURA_LEIDO ;  A4HVP7, PURA_LEIIN ;
DR   Q4QG35, PURA_LEIMA ;  Q6ACB0, PURA_LEIXX ;  Q72PA7, PURA_LEPIC ;
DR   Q8F738, PURA_LEPIN ;  B1N002, PURA_LEUCK ;  Q03W69, PURA_LEUMM ;
DR   Q92FQ5, PURA_LISIN ;  C1KV62, PURA_LISMC ;  Q725A8, PURA_LISMF ;
DR   B8DAL0, PURA_LISMH ;  Q8YAR1, PURA_LISMO ;  A0AEN2, PURA_LISW6 ;
DR   A5DSZ3, PURA_LODEL ;  B1HPK4, PURA_LYSSC ;  A4QXV8, PURA_MAGO7 ;
DR   Q2W2D1, PURA_MAGSA ;  A0L7T9, PURA_MAGSM ;  O24578, PURA_MAIZE ;
DR   A8Q0E3, PURA_MALGO ;  Q65S32, PURA_MANSM ;  A1U4C0, PURA_MARAV ;
DR   Q0AS86, PURA_MARMM ;  A6VYL0, PURA_MARMS ;  Q6F243, PURA_MESFL ;
DR   Q11DJ4, PURA_MESSB ;  A6UT04, PURA_META3 ;  Q46FF6, PURA_METBF ;
DR   Q12ZI9, PURA_METBU ;  B7L289, PURA_METC4 ;  Q606N8, PURA_METCA ;
DR   Q1H0Y6, PURA_METFK ;  Q57981, PURA_METJA ;  A4FW92, PURA_METM5 ;
DR   A9A9N1, PURA_METM6 ;  A6VH18, PURA_METM7 ;  Q8PYQ9, PURA_METMA ;
DR   Q6LXC0, PURA_METMP ;  B8IPM5, PURA_METNO ;  B1Z962, PURA_METPB ;
DR   A2SHA4, PURA_METPP ;  B1M1K0, PURA_METRJ ;  A5UN95, PURA_METS3 ;
DR   B0UJ78, PURA_METS4 ;  B8EK29, PURA_METSB ;  Q2NFM9, PURA_METST ;
DR   O26712, PURA_METTH ;  A0B8Q8, PURA_METTP ;  A6UQ77, PURA_METVS ;
DR   B0JXF6, PURA_MICAN ;  C5C8H9, PURA_MICLC ;  A9UTP3, PURA_MONBE ;
DR   Q2RG43, PURA_MOOTA ;  A0QLW6, PURA_MYCA1 ;  B1MIV1, PURA_MYCA9 ;
DR   P65881, PURA_MYCBO ;  A1KFH8, PURA_MYCBP ;  C1AK32, PURA_MYCBT ;
DR   Q2SR96, PURA_MYCCT ;  A4T142, PURA_MYCGI ;  B8ZU80, PURA_MYCLB ;
DR   O69595, PURA_MYCLE ;  B2HPW4, PURA_MYCMM ;  Q6MSC7, PURA_MYCMS ;
DR   Q73T50, PURA_MYCPA ;  Q8EVI1, PURA_MYCPE ;  A0QQH7, PURA_MYCS2 ;
DR   A3PTT9, PURA_MYCSJ ;  A1UA84, PURA_MYCSK ;  Q1BEP8, PURA_MYCSS ;
DR   A5TZ84, PURA_MYCTA ;  P65880, PURA_MYCTU ;  A0PS01, PURA_MYCUA ;
DR   A1T2W5, PURA_MYCVP ;  Q1D936, PURA_MYXXD ;  Q3ISN0, PURA_NATPD ;
DR   B2A449, PURA_NATTJ ;  B9L6S4, PURA_NAUPA ;  C7Z193, PURA_NECH7 ;
DR   Q5F9J5, PURA_NEIG1 ;  B4RK98, PURA_NEIG2 ;  A9M3P7, PURA_NEIM0 ;
DR   Q9JV25, PURA_NEIMA ;  Q9K012, PURA_NEIMB ;  A1KT71, PURA_NEIMF ;
DR   A1D1M2, PURA_NEOFI ;  Q2GEH7, PURA_NEOSM ;  Q7S604, PURA_NEUCR ;
DR   Q0AHF5, PURA_NITEC ;  Q82V29, PURA_NITEU ;  Q1QP77, PURA_NITHX ;
DR   Q2YBX2, PURA_NITMU ;  Q3J808, PURA_NITOC ;  A6Q5H2, PURA_NITSB ;
DR   Q3SNC6, PURA_NITWN ;  Q5YNL6, PURA_NOCFA ;  A1SPV6, PURA_NOCSJ ;
DR   B2J8B7, PURA_NOSP7 ;  Q8YMZ0, PURA_NOSS1 ;  Q2G4V4, PURA_NOVAD ;
DR   Q8EKX9, PURA_OCEIH ;  A6WY94, PURA_OCHA4 ;  Q04EU8, PURA_OENOB ;
DR   A2XD35, PURA_ORYSI ;  A4RYD2, PURA_OSTLU ;  Q017T9, PURA_OSTTA ;
DR   C1GUH5, PURA_PARBA ;  C1FYF6, PURA_PARBD ;  C0S3Z3, PURA_PARBP ;
DR   A6LIF5, PURA_PARD8 ;  A1AZM1, PURA_PARDP ;  A7HV25, PURA_PARL1 ;
DR   A0BD92, PURA_PARTE ;  P57889, PURA_PASMU ;  B1X5S1, PURA_PAUCH ;
DR   C6DFJ2, PURA_PECCP ;  Q03ET4, PURA_PEDPA ;  Q3A828, PURA_PELCD ;
DR   Q3B6D0, PURA_PELLD ;  B4SC75, PURA_PELPB ;  A1ALC9, PURA_PELPD ;
DR   A5CY74, PURA_PELTS ;  Q4FN13, PURA_PELUB ;  B6GWE7, PURA_PENCW ;
DR   B6QB86, PURA_PENMQ ;  A9BHV4, PURA_PETMO ;  Q0TXG3, PURA_PHANO ;
DR   B7FUM7, PURA_PHATC ;  B4RDX2, PURA_PHEZH ;  Q6LM35, PURA_PHOPR ;
DR   D0NVH9, PURA_PHYIN ;  A5DIP4, PURA_PICGU ;  C4R8E8, PURA_PICPG ;
DR   A3LYS9, PURA_PICST ;  Q6L2M3, PURA_PICTO ;  Q4YU52, PURA_PLABA ;
DR   Q4X2S8, PURA_PLACH ;  Q8IDF6, PURA_PLAF7 ;  Q9U8D3, PURA_PLAFA ;
DR   B3L781, PURA_PLAKH ;  A5K2F3, PURA_PLAVI ;  Q7RJF9, PURA_PLAYO ;
DR   B2AWF0, PURA_PODAN ;  A1VNG5, PURA_POLNA ;  B1XU85, PURA_POLNS ;
DR   Q12AC9, PURA_POLSJ ;  A4SYD1, PURA_POLSQ ;  B9IJ21, PURA_POPTR ;
DR   Q7MWW8, PURA_PORGI ;  Q6A6A3, PURA_PROAC ;  A3PBN1, PURA_PROM0 ;
DR   A2C0W6, PURA_PROM1 ;  A8G3M2, PURA_PROM2 ;  A2C7N3, PURA_PROM3 ;
DR   A9BEC8, PURA_PROM4 ;  A2BVG8, PURA_PROM5 ;  Q31C27, PURA_PROM9 ;
DR   Q7VD77, PURA_PROMA ;  B4F271, PURA_PROMH ;  Q7V6A8, PURA_PROMM ;
DR   Q7V2H1, PURA_PROMP ;  A2BPY8, PURA_PROMS ;  Q46GR9, PURA_PROMT ;
DR   A4SCU2, PURA_PROVI ;  Q48NZ7, PURA_PSE14 ;  Q15ZE1, PURA_PSEA6 ;
DR   A6VD51, PURA_PSEA7 ;  B7V201, PURA_PSEA8 ;  Q02F80, PURA_PSEAB ;
DR   Q9HUM6, PURA_PSEAE ;  Q1I454, PURA_PSEE4 ;  Q4KJ68, PURA_PSEF5 ;
DR   C3KDW8, PURA_PSEFS ;  A4XPZ3, PURA_PSEMY ;  A5W9S5, PURA_PSEP1 ;
DR   Q3KIY4, PURA_PSEPF ;  B0KKZ0, PURA_PSEPG ;  Q88DD8, PURA_PSEPK ;
DR   B1JAI0, PURA_PSEPW ;  Q87VJ9, PURA_PSESM ;  O30549, PURA_PSEST ;
DR   Q4ZYX5, PURA_PSEU2 ;  Q4FTX2, PURA_PSYA2 ;  Q1QD25, PURA_PSYCK ;
DR   A1SZK6, PURA_PSYIN ;  A5WGF9, PURA_PSYWF ;  Q9UYB3, PURA_PYRAB ;
DR   Q8U3Z2, PURA_PYRFU ;  O58187, PURA_PYRHO ;  Q5JIE6, PURA_PYRKO ;
DR   Q59726, PURA_PYRSS ;  B2VXY5, PURA_PYRTR ;  Q1LLK1, PURA_RALME ;
DR   B2U9W0, PURA_RALPJ ;  Q8Y019, PURA_RALSO ;  A9WV79, PURA_RENSM ;
DR   B3PY13, PURA_RHIE6 ;  Q2K4X9, PURA_RHIEC ;  Q1MCS2, PURA_RHIL3 ;
DR   Q98F97, PURA_RHILO ;  B5ZMS8, PURA_RHILW ;  Q92MA5, PURA_RHIME ;
DR   C3MI14, PURA_RHISN ;  Q7UHW3, PURA_RHOBA ;  B6ITA0, PURA_RHOCS ;
DR   C0ZTG3, PURA_RHOE4 ;  Q21W39, PURA_RHOFD ;  C1AWU5, PURA_RHOOB ;
DR   Q2J0H0, PURA_RHOP2 ;  Q07J18, PURA_RHOP5 ;  Q6N1V9, PURA_RHOPA ;
DR   Q20Z24, PURA_RHOPB ;  Q131X4, PURA_RHOPS ;  B3Q6W6, PURA_RHOPT ;
DR   Q2RVD8, PURA_RHORT ;  A3PL98, PURA_RHOS1 ;  Q3J0Z3, PURA_RHOS4 ;
DR   A4WQW4, PURA_RHOS5 ;  B9KKA7, PURA_RHOSK ;  Q0S555, PURA_RHOSR ;
DR   Q168S1, PURA_ROSDO ;  A1AWH8, PURA_RUTMC ;  Q21HA8, PURA_SACD2 ;
DR   A4FQK6, PURA_SACEN ;  B5F392, PURA_SALA4 ;  A9MFN5, PURA_SALAR ;
DR   Q57GL4, PURA_SALCH ;  B5FRN3, PURA_SALDC ;  B5R0P3, PURA_SALEP ;
DR   B5R9C3, PURA_SALG2 ;  B4TFB1, PURA_SALHS ;  B4T2S2, PURA_SALNS ;
DR   Q5PL58, PURA_SALPA ;  A9N4Z1, PURA_SALPB ;  C0Q6D4, PURA_SALPC ;
DR   B5BKI5, PURA_SALPK ;  Q2S1J1, PURA_SALRD ;  B4TSF7, PURA_SALSV ;
DR   P65883, PURA_SALTI ;  P65882, PURA_SALTY ;  Q5D8V5, PURA_SCHJA ;
DR   B6JUV1, PURA_SCHJY ;  C4QCD2, PURA_SCHMA ;  Q02787, PURA_SCHPO ;
DR   A8G8V4, PURA_SERP5 ;  A1SA65, PURA_SHEAM ;  Q12RX5, PURA_SHEDO ;
DR   Q07XS1, PURA_SHEFN ;  B0TUV4, PURA_SHEHH ;  A3QI59, PURA_SHELP ;
DR   Q8EAG5, PURA_SHEON ;  A8H8L8, PURA_SHEPA ;  B8CIP5, PURA_SHEPW ;
DR   B1KIH9, PURA_SHEWM ;  B2TY52, PURA_SHIB3 ;  Q31TA7, PURA_SHIBS ;
DR   Q328F6, PURA_SHIDS ;  Q0SXA5, PURA_SHIF8 ;  Q83P33, PURA_SHIFL ;
DR   Q3YUG6, PURA_SHISS ;  Q5LTU4, PURA_SILPO ;  Q1GF65, PURA_SILST ;
DR   A6UCR6, PURA_SINMW ;  Q2NW58, PURA_SODGM ;  A9XLG1, PURA_SOLBU ;
DR   Q026Q7, PURA_SOLUE ;  A9G5S0, PURA_SORC5 ;  D1ZRH0, PURA_SORMK ;
DR   Q1GVU1, PURA_SPHAL ;  A5VFF3, PURA_SPHWW ;  P52150, PURA_SPICI ;
DR   Q5HJX8, PURA_STAAC ;  P65884, PURA_STAAM ;  P99099, PURA_STAAN ;
DR   Q6GKS8, PURA_STAAR ;  Q6GD73, PURA_STAAS ;  Q8NYX6, PURA_STAAW ;
DR   Q5HK16, PURA_STAEQ ;  Q8CQK1, PURA_STAES ;  Q4LAK0, PURA_STAHJ ;
DR   Q4A164, PURA_STAS1 ;  Q3JZ68, PURA_STRA1 ;  P65885, PURA_STRA3 ;
DR   P65886, PURA_STRA5 ;  Q82ER6, PURA_STRAW ;  Q9X8P6, PURA_STRCO ;
DR   C0MAE4, PURA_STRE4 ;  A8AZM9, PURA_STRGC ;  B1VMC3, PURA_STRGG ;
DR   B4SS80, PURA_STRM5 ;  Q8DW14, PURA_STRMU ;  Q9A1P8, PURA_STRP1 ;
DR   Q04N48, PURA_STRP2 ;  P0DD54, PURA_STRP3 ;  Q5XE45, PURA_STRP6 ;
DR   Q8P2U1, PURA_STRP8 ;  Q1JNS3, PURA_STRPC ;  Q1JIX0, PURA_STRPD ;
DR   Q1J8S0, PURA_STRPF ;  A2RCA2, PURA_STRPG ;  B8ZJJ5, PURA_STRPJ ;
DR   Q48VK8, PURA_STRPM ;  P65887, PURA_STRPN ;  P0DD55, PURA_STRPQ ;
DR   B5XJH8, PURA_STRPZ ;  P65888, PURA_STRR6 ;  A4W440, PURA_STRS2 ;
DR   C0MFY0, PURA_STRS7 ;  A3CQU5, PURA_STRSV ;  Q5LXQ5, PURA_STRT1 ;
DR   Q5M2A7, PURA_STRT2 ;  Q03IE5, PURA_STRTD ;  B9DT31, PURA_STRU0 ;
DR   Q30UH5, PURA_SULDN ;  A6Q6M5, PURA_SULNB ;  Q67J55, PURA_SYMTH ;
DR   Q2LSI8, PURA_SYNAS ;  Q31KI0, PURA_SYNE7 ;  A0LHR1, PURA_SYNFM ;
DR   Q2JQX5, PURA_SYNJA ;  Q2JQ36, PURA_SYNJB ;  B1XIL5, PURA_SYNP2 ;
DR   Q5N1D4, PURA_SYNP6 ;  A5GJD1, PURA_SYNPW ;  Q7U5D4, PURA_SYNPX ;
DR   A5GSC3, PURA_SYNR3 ;  Q0I8J6, PURA_SYNS3 ;  Q3AWR7, PURA_SYNS9 ;
DR   Q3ALR7, PURA_SYNSC ;  Q0ATY3, PURA_SYNWW ;  P73290, PURA_SYNY3 ;
DR   B8M3A8, PURA_TALSN ;  C5BRH0, PURA_TERTT ;  B7IG20, PURA_THEAB ;
DR   Q9HIH2, PURA_THEAC ;  Q4UAQ0, PURA_THEAN ;  Q8DLG2, PURA_THEEB ;
DR   Q47KH7, PURA_THEFY ;  C5A5E2, PURA_THEGJ ;  A8F801, PURA_THELT ;
DR   A6LJT4, PURA_THEM4 ;  Q9X0I1, PURA_THEMA ;  B6YWD6, PURA_THEON ;
DR   B0K8D7, PURA_THEP3 ;  Q4N3F4, PURA_THEPA ;  B0K5I0, PURA_THEPX ;
DR   B9KYV8, PURA_THERP ;  C6A270, PURA_THESM ;  Q72GT4, PURA_THET2 ;
DR   Q5SLS1, PURA_THET8 ;  Q8R6T8, PURA_THETN ;  Q97C15, PURA_THEVO ;
DR   B5YKK9, PURA_THEYD ;  Q31GN4, PURA_THICR ;  Q3SL57, PURA_THIDA ;
DR   P52151, PURA_THIFE ;  B8GND3, PURA_THISH ;  Q6T7E8, PURA_TOBAC ;
DR   C4L9M5, PURA_TOLAT ;  B3S0D3, PURA_TRIAD ;  Q10ZD0, PURA_TRIEI ;
DR   Q83H67, PURA_TROW8 ;  Q83FF0, PURA_TROWT ;  Q386E7, PURA_TRYB2 ;
DR   D0A6J7, PURA_TRYB9 ;  C4JYB4, PURA_UNCRE ;  B1H0H8, PURA_UNCTG ;
DR   Q4P7R2, PURA_USTMA ;  A7TID0, PURA_VANPO ;  C5CXH7, PURA_VARPS ;
DR   A1WMN5, PURA_VEREI ;  A5CWQ5, PURA_VESOH ;  A5F534, PURA_VIBC3 ;
DR   Q9KNX8, PURA_VIBCH ;  C3LRR4, PURA_VIBCM ;  Q5E2D3, PURA_VIBF1 ;
DR   P40607, PURA_VIBPA ;  Q8DCU4, PURA_VIBVU ;  Q7MH07, PURA_VIBVY ;
DR   O24396, PURA_WHEAT ;  Q8D322, PURA_WIGBR ;  Q73I44, PURA_WOLPM ;
DR   B3CL83, PURA_WOLPP ;  Q7M7V8, PURA_WOLSU ;  Q5GT12, PURA_WOLTR ;
DR   C0R2U5, PURA_WOLWR ;  Q8PNB5, PURA_XANAC ;  Q3BWF4, PURA_XANC5 ;
DR   Q4URT6, PURA_XANC8 ;  B0RYD5, PURA_XANCB ;  Q8PBR6, PURA_XANCP ;
DR   Q2P782, PURA_XANOM ;  B2SNJ3, PURA_XANOP ;  Q5H4F2, PURA_XANOR ;
DR   B2I7V8, PURA_XYLF2 ;  Q9PG47, PURA_XYLFA ;  B0U498, PURA_XYLFM ;
DR   Q87B33, PURA_XYLFT ;  Q6C482, PURA_YARLI ;  B3LP64, PURA_YEAS1 ;
DR   C7GPD7, PURA_YEAS2 ;  B5VQJ1, PURA_YEAS6 ;  A6ZRM0, PURA_YEAS7 ;
DR   C8ZG13, PURA_YEAS8 ;  P80210, PURA_YEAST ;  A1JIS0, PURA_YERE8 ;
DR   A7FMX4, PURA_YERP3 ;  Q1C105, PURA_YERPA ;  B2K2K4, PURA_YERPB ;
DR   Q8ZIV7, PURA_YERPE ;  A9QYM6, PURA_YERPG ;  Q1CEG0, PURA_YERPN ;
DR   A4TRN4, PURA_YERPP ;  Q66FB0, PURA_YERPS ;  B1JMN3, PURA_YERPY ;
DR   C5DYR7, PURA_ZYGRC ;  Q5NLU9, PURA_ZYMMO ;
//
ID   6.3.4.5
DE   Argininosuccinate synthase.
AN   Arginine succinate synthetase.
AN   Argininosuccinate synthetase.
AN   Citrulline--aspartate ligase.
CA   ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-
CA   (L-arginino)succinate.
PR   PROSITE; PDOC00488;
DR   Q1MEZ8, ASSY1_RHIL3;  Q1MAN9, ASSY2_RHIL3;  B0CCQ2, ASSY_ACAM1 ;
DR   A1TNA2, ASSY_ACIAC ;  Q1IIZ2, ASSY_ACIBL ;  A0LUB9, ASSY_ACIC1 ;
DR   C1F510, ASSY_ACIC5 ;  A5FWI5, ASSY_ACICJ ;  B9MBJ2, ASSY_ACIET ;
DR   A1W9F9, ASSY_ACISJ ;  A6VN06, ASSY_ACTSZ ;  Q0IFL5, ASSY_AEDAE ;
DR   A0KFV3, ASSY_AERHH ;  A4SIM5, ASSY_AERS4 ;  Q8UC31, ASSY_AGRT5 ;
DR   Q0VRM5, ASSY_ALCBS ;  Q0AB32, ASSY_ALHEH ;  B6EMN8, ASSY_ALISL ;
DR   A6TL10, ASSY_ALKMQ ;  B9MRP5, ASSY_ANATD ;  Q3MBE6, ASSY_ANAVT ;
DR   B7GGR4, ASSY_ANOFW ;  Q7PR38, ASSY_ANOGA ;  O67213, ASSY_AQUAE ;
DR   Q9SZX3, ASSY_ARATH ;  A8EUB2, ASSY_ARCB4 ;  O28032, ASSY_ARCFU ;
DR   Q5P0Z7, ASSY_AROAE ;  A1R591, ASSY_ARTAT ;  B8HGC9, ASSY_ARTCA ;
DR   A0JV26, ASSY_ARTS2 ;  A8IQ54, ASSY_AZOC5 ;  A1K7J8, ASSY_AZOSB ;
DR   C1DQV2, ASSY_AZOVD ;  A7Z7M0, ASSY_BACA2 ;  C3PB97, ASSY_BACAA ;
DR   C3L9T6, ASSY_BACAC ;  A0RJM4, ASSY_BACAH ;  Q81KV7, ASSY_BACAN ;
DR   B7JS06, ASSY_BACC0 ;  P61520, ASSY_BACC1 ;  B7IK29, ASSY_BACC2 ;
DR   C1EUX9, ASSY_BACC3 ;  B7H6Y5, ASSY_BACC4 ;  B7HRS7, ASSY_BACC7 ;
DR   A7GTR5, ASSY_BACCN ;  B9J0E1, ASSY_BACCQ ;  Q817C6, ASSY_BACCR ;
DR   Q633G4, ASSY_BACCZ ;  Q9K820, ASSY_BACHD ;  Q6HCP7, ASSY_BACHK ;
DR   Q65G67, ASSY_BACLD ;  A8FG70, ASSY_BACP2 ;  Q5WED8, ASSY_BACSK ;
DR   O34347, ASSY_BACSU ;  A9VKE1, ASSY_BACWK ;  A1UUF5, ASSY_BARBK ;
DR   A9IL50, ASSY_BART1 ;  A1A1W7, ASSY_BIFAA ;  B3DSY7, ASSY_BIFLD ;
DR   Q8G5F2, ASSY_BIFLO ;  B7GTP0, ASSY_BIFLS ;  Q7WKW7, ASSY_BORBR ;
DR   Q7W7H8, ASSY_BORPA ;  A9IQ90, ASSY_BORPD ;  Q7VTJ9, ASSY_BORPE ;
DR   P14568, ASSY_BOVIN ;  C0R1H5, ASSY_BRAHW ;  P59607, ASSY_BRAJA ;
DR   A5E8P0, ASSY_BRASB ;  A4YJX9, ASSY_BRASO ;  C0Z6S0, ASSY_BREBN ;
DR   B2S7X3, ASSY_BRUA1 ;  Q2YPQ8, ASSY_BRUA2 ;  Q57FU2, ASSY_BRUAB ;
DR   A9M6S7, ASSY_BRUC2 ;  C0RGD6, ASSY_BRUMB ;  Q8YEK8, ASSY_BRUME ;
DR   A5VN19, ASSY_BRUO2 ;  B0CII7, ASSY_BRUSI ;  Q8G376, ASSY_BRUSU ;
DR   B8D8K8, ASSY_BUCA5 ;  P57158, ASSY_BUCAI ;  Q8KA60, ASSY_BUCAP ;
DR   B8D6W2, ASSY_BUCAT ;  P59412, ASSY_BUCBP ;  Q058D6, ASSY_BUCCC ;
DR   B1Z0E2, ASSY_BURA4 ;  Q1BLH4, ASSY_BURCA ;  B1K5H3, ASSY_BURCC ;
DR   A0AYH4, ASSY_BURCH ;  B4EM48, ASSY_BURCJ ;  Q0B4C4, ASSY_BURCM ;
DR   P59608, ASSY_BURM1 ;  A3MNB7, ASSY_BURM7 ;  A2S7V6, ASSY_BURM9 ;
DR   Q62EQ4, ASSY_BURMA ;  A1V7X3, ASSY_BURMS ;  A3NQI1, ASSY_BURP0 ;
DR   Q3JWY8, ASSY_BURP1 ;  A3N4T7, ASSY_BURP6 ;  B2JP23, ASSY_BURP8 ;
DR   B2SY63, ASSY_BURPP ;  Q63U95, ASSY_BURPS ;  Q392V6, ASSY_BURS3 ;
DR   Q2T1W2, ASSY_BURTA ;  A4JLD9, ASSY_BURVG ;  Q13UR1, ASSY_BURXL ;
DR   A4XKG4, ASSY_CALS8 ;  A7ZDF2, ASSY_CAMC1 ;  A7GYN4, ASSY_CAMC5 ;
DR   A0RP84, ASSY_CAMFF ;  A7I281, ASSY_CAMHC ;  A8FL83, ASSY_CAMJ8 ;
DR   A7H4E9, ASSY_CAMJD ;  Q9PHK7, ASSY_CAMJE ;  A1VZ24, ASSY_CAMJJ ;
DR   Q5HVA9, ASSY_CAMJR ;  B9KG97, ASSY_CAMLR ;  Q3A9W5, ASSY_CARHZ ;
DR   Q05FN6, ASSY_CARRP ;  B8GXL9, ASSY_CAUCN ;  Q9ABU1, ASSY_CAUCR ;
DR   B0T3Z9, ASSY_CAUSK ;  Q5ZJ23, ASSY_CHICK ;  Q3ASI2, ASSY_CHLCH ;
DR   B3ECP2, ASSY_CHLL2 ;  B3QN91, ASSY_CHLP8 ;  B3EJ62, ASSY_CHLPB ;
DR   A1BG29, ASSY_CHLPD ;  Q8KDE0, ASSY_CHLTE ;  Q1QVN0, ASSY_CHRSD ;
DR   Q7NWJ5, ASSY_CHRVO ;  A8AQ63, ASSY_CITK8 ;  A5CSJ0, ASSY_CLAM3 ;
DR   B0RHD5, ASSY_CLAMS ;  Q97KE6, ASSY_CLOAB ;  A7FWU6, ASSY_CLOB1 ;
DR   C3L1U3, ASSY_CLOB6 ;  A6M1Z4, ASSY_CLOB8 ;  B2UYI0, ASSY_CLOBA ;
DR   B2TQ23, ASSY_CLOBB ;  A5I5A4, ASSY_CLOBH ;  C1FU68, ASSY_CLOBJ ;
DR   B1IK08, ASSY_CLOBK ;  A7GGQ9, ASSY_CLOBL ;  B1KXY1, ASSY_CLOBM ;
DR   Q186Z6, ASSY_CLOD6 ;  B9E0B1, ASSY_CLOK1 ;  A5N6U2, ASSY_CLOK5 ;
DR   A0Q1Z2, ASSY_CLONN ;  Q0TTA5, ASSY_CLOP1 ;  Q8XMJ7, ASSY_CLOPE ;
DR   A9KHL4, ASSY_CLOPH ;  P59602, ASSY_CLOTE ;  A3DBU1, ASSY_CLOTH ;
DR   Q489P3, ASSY_COLP3 ;  P61521, ASSY_CORDI ;  Q8FTM9, ASSY_COREF ;
DR   A4QDZ4, ASSY_CORGB ;  O85176, ASSY_CORGL ;  Q4JVZ8, ASSY_CORJK ;
DR   C4LIE1, ASSY_CORK4 ;  B1VH30, ASSY_CORU7 ;  B1WTK3, ASSY_CYAA5 ;
DR   B8HSA9, ASSY_CYAP4 ;  B7JVH4, ASSY_CYAP8 ;  Q66I24, ASSY_DANRE ;
DR   Q47BM0, ASSY_DECAR ;  Q3Z727, ASSY_DEHE1 ;  A5FQ73, ASSY_DEHSB ;
DR   Q3ZYG0, ASSY_DEHSC ;  C1CXR6, ASSY_DEIDV ;  Q1IWM3, ASSY_DEIGD ;
DR   Q9RWJ4, ASSY_DEIRA ;  A9BM60, ASSY_DELAS ;  B8FH30, ASSY_DESAA ;
DR   Q30YB8, ASSY_DESDG ;  B8FWX2, ASSY_DESHD ;  Q24ZG8, ASSY_DESHY ;
DR   Q6AR59, ASSY_DESPS ;  A4J173, ASSY_DESRM ;  P61522, ASSY_DESVH ;
DR   B8DN64, ASSY_DESVM ;  A1VEQ0, ASSY_DESVV ;  P0C1A1, ASSY_DICD3 ;
DR   B5YAL9, ASSY_DICT6 ;  B8E0N9, ASSY_DICTD ;  A8LPE0, ASSY_DINSH ;
DR   O97069, ASSY_DROME ;  A7ZS69, ASSY_ECO24 ;  B7UJ66, ASSY_ECO27 ;
DR   B7MB92, ASSY_ECO45 ;  B7LHN6, ASSY_ECO55 ;  Q8X9M0, ASSY_ECO57 ;
DR   B5YS62, ASSY_ECO5E ;  B7NKP0, ASSY_ECO7I ;  B7N0V6, ASSY_ECO81 ;
DR   B7M079, ASSY_ECO8A ;  C4ZSR2, ASSY_ECOBW ;  B1XGY3, ASSY_ECODH ;
DR   A8A4Y7, ASSY_ECOHS ;  A1AG76, ASSY_ECOK1 ;  Q0TCT8, ASSY_ECOL5 ;
DR   P0A6E5, ASSY_ECOL6 ;  B1IQV0, ASSY_ECOLC ;  P0A6E4, ASSY_ECOLI ;
DR   B7NDF7, ASSY_ECOLU ;  B6I1P6, ASSY_ECOSE ;  B1LFS3, ASSY_ECOSM ;
DR   Q1R6G5, ASSY_ECOUT ;  C5BC58, ASSY_EDWI9 ;  Q3YS95, ASSY_EHRCJ ;
DR   Q2GGE6, ASSY_EHRCR ;  Q5FH27, ASSY_EHRRG ;  Q5HBF2, ASSY_EHRRW ;
DR   A4WEY6, ASSY_ENT38 ;  A7ML85, ASSY_ENTS8 ;  P0C1A0, ASSY_ERWCH ;
DR   Q6DAZ8, ASSY_ERWCT ;  B2VGA8, ASSY_ERWT9 ;  Q2N9H9, ASSY_ERYLH ;
DR   B7LR40, ASSY_ESCF3 ;  C4Z4C1, ASSY_EUBE2 ;  C4Z9C9, ASSY_EUBR3 ;
DR   B1YJ35, ASSY_EXIS2 ;  Q0RFB2, ASSY_FRAAA ;  Q2J866, ASSY_FRASC ;
DR   A8LE46, ASSY_FRASN ;  C1A3S5, ASSY_GEMAT ;  B5ED13, ASSY_GEOBB ;
DR   Q5KW94, ASSY_GEOKA ;  Q39Z72, ASSY_GEOMG ;  B9M374, ASSY_GEOSF ;
DR   P61523, ASSY_GEOSL ;  C6E6Y6, ASSY_GEOSM ;  C5D679, ASSY_GEOSW ;
DR   A4IRS3, ASSY_GEOTN ;  A5GDA4, ASSY_GEOUR ;  Q7NCP5, ASSY_GLOVI ;
DR   A9HIQ4, ASSY_GLUDA ;  Q5FUA8, ASSY_GLUOX ;  Q0BVJ1, ASSY_GRABC ;
DR   Q4QJM0, ASSY_HAEI8 ;  A5UBF3, ASSY_HAEIE ;  A5UFF8, ASSY_HAEIG ;
DR   P44315, ASSY_HAEIN ;  Q0I4M1, ASSY_HAES1 ;  B0UW58, ASSY_HAES2 ;
DR   Q2SCE5, ASSY_HAHCH ;  A1WUZ5, ASSY_HALHL ;  Q5UZ46, ASSY_HALMA ;
DR   Q9HMQ2, ASSY_HALSA ;  Q18E36, ASSY_HALWD ;  Q7VGU9, ASSY_HELHP ;
DR   Q8GDU2, ASSY_HELMO ;  A4G3H1, ASSY_HERAR ;  P00966, ASSY_HUMAN ;
DR   A2BJL6, ASSY_HYPBU ;  Q0BWI1, ASSY_HYPNA ;  Q5QWZ9, ASSY_IDILO ;
DR   A8AA65, ASSY_IGNH4 ;  A6SW90, ASSY_JANMA ;  Q28WC8, ASSY_JANSC ;
DR   A6W614, ASSY_KINRD ;  B5XSX1, ASSY_KLEP3 ;  A6TEJ0, ASSY_KLEP7 ;
DR   B2GKD7, ASSY_KOCRD ;  Q033U7, ASSY_LACC3 ;  P57799, ASSY_LACLA ;
DR   Q59491, ASSY_LACLM ;  Q032X6, ASSY_LACLS ;  P59603, ASSY_LACPL ;
DR   A5VJH1, ASSY_LACRD ;  B2G6Y6, ASSY_LACRJ ;  Q1WV65, ASSY_LACS1 ;
DR   C1D9Q4, ASSY_LARHH ;  Q1MQL7, ASSY_LAWIP ;  Q5X7P9, ASSY_LEGPA ;
DR   A5IHA3, ASSY_LEGPC ;  Q5ZY78, ASSY_LEGPH ;  Q5WZ50, ASSY_LEGPL ;
DR   Q6ACL1, ASSY_LEIXX ;  B0S9J6, ASSY_LEPBA ;  Q04P84, ASSY_LEPBJ ;
DR   Q056F0, ASSY_LEPBL ;  B0SJR2, ASSY_LEPBP ;  P61524, ASSY_LEPIC ;
DR   Q8EYP7, ASSY_LEPIN ;  B1MZP4, ASSY_LEUCK ;  Q03W70, ASSY_LEUMM ;
DR   Q929S9, ASSY_LISIN ;  C1KX43, ASSY_LISMC ;  Q71XS4, ASSY_LISMF ;
DR   B8DH28, ASSY_LISMH ;  Q8Y5H2, ASSY_LISMO ;  A0AKJ7, ASSY_LISW6 ;
DR   Q2W896, ASSY_MAGSA ;  A0LE34, ASSY_MAGSM ;  Q65SH4, ASSY_MANSM ;
DR   A1U3U4, ASSY_MARAV ;  Q0AKJ6, ASSY_MARMM ;  A6VVI2, ASSY_MARMS ;
DR   Q11D10, ASSY_MESSB ;  Q8TNY5, ASSY_METAC ;  P13257, ASSY_METBA ;
DR   Q469Z8, ASSY_METBF ;  Q12XK3, ASSY_METBU ;  Q609X7, ASSY_METCA ;
DR   Q1H0L1, ASSY_METFK ;  Q2FLD8, ASSY_METHJ ;  Q60174, ASSY_METJA ;
DR   Q8TWU0, ASSY_METKA ;  Q8Q0U5, ASSY_METMA ;  P61527, ASSY_METMP ;
DR   A2SK99, ASSY_METPP ;  A4YI75, ASSY_METS5 ;  B8ESL2, ASSY_METSB ;
DR   Q2NEC4, ASSY_METST ;  O27322, ASSY_METTH ;  P13256, ASSY_METVA ;
DR   B0JM14, ASSY_MICAN ;  C5CAM5, ASSY_MICLC ;  Q2RG67, ASSY_MOOTA ;
DR   Q9K4Y8, ASSY_MORAB ;  Q9K4Z3, ASSY_MORPR ;  P16460, ASSY_MOUSE ;
DR   A0QHA8, ASSY_MYCA1 ;  P63643, ASSY_MYCBO ;  A1KJ75, ASSY_MYCBP ;
DR   C1ANT1, ASSY_MYCBT ;  A4T9W4, ASSY_MYCGI ;  Q9CC10, ASSY_MYCLE ;
DR   B2HR32, ASSY_MYCMM ;  P61525, ASSY_MYCPA ;  A0QYS6, ASSY_MYCS2 ;
DR   A3Q0T3, ASSY_MYCSJ ;  A1UH96, ASSY_MYCSK ;  Q1B7R1, ASSY_MYCSS ;
DR   A5U315, ASSY_MYCTA ;  P63642, ASSY_MYCTU ;  A0PP79, ASSY_MYCUA ;
DR   A1TAA6, ASSY_MYCVP ;  Q3IME2, ASSY_NATPD ;  Q5F5G5, ASSY_NEIG1 ;
DR   B4RQS8, ASSY_NEIG2 ;  A9M4B1, ASSY_NEIM0 ;  Q9JWM1, ASSY_NEIMA ;
DR   Q9JXC1, ASSY_NEIMB ;  A1KWJ8, ASSY_NEIMF ;  Q0AEE4, ASSY_NITEC ;
DR   Q82UP5, ASSY_NITEU ;  Q1QHE6, ASSY_NITHX ;  Q2YA75, ASSY_NITMU ;
DR   Q3J9C8, ASSY_NITOC ;  A6Q3P9, ASSY_NITSB ;  Q3SNT5, ASSY_NITWN ;
DR   Q5YYD3, ASSY_NOCFA ;  A1SJJ3, ASSY_NOCSJ ;  B2J6U2, ASSY_NOSP7 ;
DR   Q8YMX6, ASSY_NOSS1 ;  Q2G933, ASSY_NOVAD ;  Q8ELT8, ASSY_OCEIH ;
DR   A6WV13, ASSY_OCHA4 ;  Q04FC0, ASSY_OENOB ;  B6JAT0, ASSY_OLICO ;
DR   A1AZB7, ASSY_PARDP ;  A7HSW4, ASSY_PARL1 ;  P57877, ASSY_PASMU ;
DR   P55744, ASSY_PECCC ;  C6DIG9, ASSY_PECCP ;  Q3A1V1, ASSY_PELCD ;
DR   Q3B425, ASSY_PELLD ;  B4S9U5, ASSY_PELPB ;  A1ATU4, ASSY_PELPD ;
DR   A5D510, ASSY_PELTS ;  Q4FNX4, ASSY_PELUB ;  Q7MYD8, ASSY_PHOLL ;
DR   Q6LVG8, ASSY_PHOPR ;  Q6L1N7, ASSY_PICTO ;  A1VL71, ASSY_POLNA ;
DR   B1XRS6, ASSY_POLNS ;  Q12D55, ASSY_POLSJ ;  A4SZQ2, ASSY_POLSQ ;
DR   B4S7R9, ASSY_PROA2 ;  A3PFJ6, ASSY_PROM0 ;  A2C5I6, ASSY_PROM1 ;
DR   A8G7L2, ASSY_PROM2 ;  A2CE29, ASSY_PROM3 ;  A9BDR3, ASSY_PROM4 ;
DR   A2BZ94, ASSY_PROM5 ;  Q317T4, ASSY_PROM9 ;  Q7V9F8, ASSY_PROMA ;
DR   Q7V3S9, ASSY_PROMM ;  Q7UZG0, ASSY_PROMP ;  A2BTT9, ASSY_PROMS ;
DR   Q46I72, ASSY_PROMT ;  A4SEI8, ASSY_PROVI ;  Q48F14, ASSY_PSE14 ;
DR   Q15X83, ASSY_PSEA6 ;  A6V1S1, ASSY_PSEA7 ;  B7UVV5, ASSY_PSEA8 ;
DR   Q02QZ6, ASSY_PSEAB ;  Q9HY84, ASSY_PSEAE ;  Q1IE03, ASSY_PSEE4 ;
DR   Q4K749, ASSY_PSEF5 ;  C3KBZ2, ASSY_PSEFS ;  Q3IHT8, ASSY_PSEHT ;
DR   A4XS43, ASSY_PSEMY ;  P85910, ASSY_PSEMZ ;  A5VZI0, ASSY_PSEP1 ;
DR   Q3K7K0, ASSY_PSEPF ;  B0KUE7, ASSY_PSEPG ;  P59604, ASSY_PSEPK ;
DR   B1J4I4, ASSY_PSEPW ;  Q87XM3, ASSY_PSESM ;  Q4ZPK0, ASSY_PSEU2 ;
DR   A4VIU7, ASSY_PSEU5 ;  Q4FR79, ASSY_PSYA2 ;  Q1Q9L2, ASSY_PSYCK ;
DR   A1SRI3, ASSY_PSYIN ;  A5WG08, ASSY_PSYWF ;  Q8ZU97, ASSY_PYRAE ;
DR   Q8U484, ASSY_PYRFU ;  B2UBA3, ASSY_RALPJ ;  Q8XWC1, ASSY_RALSO ;
DR   P09034, ASSY_RAT   ;  A9WQ90, ASSY_RENSM ;  Q2K3B7, ASSY_RHIEC ;
DR   Q98E81, ASSY_RHILO ;  Q92L73, ASSY_RHIME ;  Q7UFW4, ASSY_RHOBA ;
DR   B6IVD0, ASSY_RHOCS ;  C1A051, ASSY_RHOE4 ;  Q93JQ8, ASSY_RHOFA ;
DR   C1ASZ6, ASSY_RHOOB ;  Q07VN9, ASSY_RHOP5 ;  Q6NCS7, ASSY_RHOPA ;
DR   Q21DC6, ASSY_RHOPB ;  Q13D88, ASSY_RHOPS ;  B3Q9D3, ASSY_RHOPT ;
DR   Q2RMV0, ASSY_RHORT ;  A3PNQ9, ASSY_RHOS1 ;  Q3IYJ1, ASSY_RHOS4 ;
DR   A4WVX3, ASSY_RHOS5 ;  B9KPT5, ASSY_RHOSK ;  Q0SI58, ASSY_RHOSR ;
DR   A7NPB0, ASSY_ROSCS ;  Q16D10, ASSY_ROSDO ;  A5V0J9, ASSY_ROSS1 ;
DR   Q1AS35, ASSY_RUBXD ;  A1AVI7, ASSY_RUTMC ;  Q21HZ6, ASSY_SACD2 ;
DR   A4FDS0, ASSY_SACEN ;  B5F6U1, ASSY_SALA4 ;  A8LYQ9, ASSY_SALAI ;
DR   A9MP33, ASSY_SALAR ;  B5FI16, ASSY_SALDC ;  B5QZW1, ASSY_SALEP ;
DR   B4TJ09, ASSY_SALHS ;  B4T702, ASSY_SALNS ;  A9N735, ASSY_SALPB ;
DR   B4TWE1, ASSY_SALSV ;  Q8Z3H5, ASSY_SALTI ;  Q8ZLT0, ASSY_SALTY ;
DR   O94354, ASSY_SCHPO ;  A8GL82, ASSY_SERP5 ;  A1S264, ASSY_SHEAM ;
DR   B8EBG0, ASSY_SHEB2 ;  A3DA23, ASSY_SHEB5 ;  A6WTS0, ASSY_SHEB8 ;
DR   A9KTY7, ASSY_SHEB9 ;  Q12SM7, ASSY_SHEDO ;  Q089K8, ASSY_SHEFN ;
DR   B0TL85, ASSY_SHEHH ;  A3Q9C9, ASSY_SHELP ;  Q8EK28, ASSY_SHEON ;
DR   A8GZ21, ASSY_SHEPA ;  A4YBT9, ASSY_SHEPC ;  B8CNI0, ASSY_SHEPW ;
DR   A0L251, ASSY_SHESA ;  A8G1A4, ASSY_SHESH ;  Q0HDU8, ASSY_SHESM ;
DR   Q0I061, ASSY_SHESR ;  A1RPR6, ASSY_SHESW ;  B1KND6, ASSY_SHEWM ;
DR   B2U204, ASSY_SHIB3 ;  Q31W50, ASSY_SHIBS ;  Q32BG2, ASSY_SHIDS ;
DR   Q0T0B0, ASSY_SHIF8 ;  P59609, ASSY_SHIFL ;  Q3YX68, ASSY_SHISS ;
DR   Q5LWG3, ASSY_SILPO ;  Q1GCK1, ASSY_SILST ;  A6UE09, ASSY_SINMW ;
DR   Q01Y56, ASSY_SOLUE ;  Q1GVV6, ASSY_SPHAL ;  A5VAK5, ASSY_SPHWW ;
DR   A7X0H5, ASSY_STAA1 ;  A6U068, ASSY_STAA2 ;  Q2FIB4, ASSY_STAA3 ;
DR   Q2FZU1, ASSY_STAA8 ;  A5IRD9, ASSY_STAA9 ;  Q2YWS4, ASSY_STAAB ;
DR   Q5HHC4, ASSY_STAAC ;  A6QFH2, ASSY_STAAE ;  P63644, ASSY_STAAM ;
DR   P63645, ASSY_STAAN ;  Q6GIC7, ASSY_STAAR ;  Q6GAW5, ASSY_STAAS ;
DR   A8Z067, ASSY_STAAT ;  Q8NXF2, ASSY_STAAW ;  B9DIU4, ASSY_STACT ;
DR   Q5HQK0, ASSY_STAEQ ;  Q8CPU3, ASSY_STAES ;  Q4L4X7, ASSY_STAHJ ;
DR   Q49WA0, ASSY_STAS1 ;  Q3K3Q4, ASSY_STRA1 ;  Q8E7N1, ASSY_STRA3 ;
DR   Q8E272, ASSY_STRA5 ;  Q827Z1, ASSY_STRAW ;  P50986, ASSY_STRCL ;
DR   P24532, ASSY_STRCO ;  A8AUN6, ASSY_STRGC ;  B1W3B3, ASSY_STRGG ;
DR   Q06734, ASSY_STRLA ;  Q8CWZ0, ASSY_STRMU ;  Q04MW7, ASSY_STRP2 ;
DR   B1I814, ASSY_STRPI ;  Q8DRI5, ASSY_STRR6 ;  A4W488, ASSY_STRS2 ;
DR   A3CQQ4, ASSY_STRSV ;  A4VXZ4, ASSY_STRSY ;  Q5LXZ8, ASSY_STRT1 ;
DR   Q5M2K2, ASSY_STRT2 ;  Q03IP8, ASSY_STRTD ;  B9DVV9, ASSY_STRU0 ;
DR   Q4J8F1, ASSY_SULAC ;  Q30QT1, ASSY_SULDN ;  A6QAX6, ASSY_SULNB ;
DR   Q9UX31, ASSY_SULSO ;  Q970V0, ASSY_SULTO ;  Q67KE1, ASSY_SYMTH ;
DR   Q2LT97, ASSY_SYNAS ;  Q31SC8, ASSY_SYNE7 ;  A0LEB2, ASSY_SYNFM ;
DR   Q2JWE1, ASSY_SYNJA ;  Q2JKS2, ASSY_SYNJB ;  B1XN65, ASSY_SYNP2 ;
DR   Q5N1Z2, ASSY_SYNP6 ;  A5GPT0, ASSY_SYNPW ;  Q7U3B9, ASSY_SYNPX ;
DR   A5GX16, ASSY_SYNR3 ;  Q0I607, ASSY_SYNS3 ;  Q3AVL9, ASSY_SYNS9 ;
DR   Q3AG78, ASSY_SYNSC ;  P77973, ASSY_SYNY3 ;  Q9HKF1, ASSY_THEAC ;
DR   Q8DKY7, ASSY_THEEB ;  Q47N84, ASSY_THEFY ;  A8F446, ASSY_THELT ;
DR   Q9X2A1, ASSY_THEMA ;  B9K8S7, ASSY_THENN ;  A5ILL1, ASSY_THEP1 ;
DR   B0KBW5, ASSY_THEP3 ;  B0K4D8, ASSY_THEPX ;  B1LAP4, ASSY_THESQ ;
DR   P61526, ASSY_THET2 ;  P59846, ASSY_THET8 ;  Q8R7C2, ASSY_THETN ;
DR   Q97A55, ASSY_THEVO ;  Q31H63, ASSY_THICR ;  Q3SHT1, ASSY_THIDA ;
DR   Q117P0, ASSY_TRIEI ;  B1H0L3, ASSY_UNCTG ;  C5CUG9, ASSY_VARPS ;
DR   A5CXM9, ASSY_VESOH ;  A5F4Z4, ASSY_VIBC3 ;  Q9KNT8, ASSY_VIBCH ;
DR   C3LRV3, ASSY_VIBCM ;  Q5E2E7, ASSY_VIBF1 ;  B5FBP4, ASSY_VIBFM ;
DR   A7MXB9, ASSY_VIBHB ;  P59605, ASSY_VIBPA ;  Q8DCN0, ASSY_VIBVU ;
DR   Q7MH72, ASSY_VIBVY ;  Q7M7P6, ASSY_WOLSU ;  Q8PK26, ASSY_XANAC ;
DR   Q8P8J4, ASSY_XANCP ;  A7IGW4, ASSY_XANP2 ;  Q7ZWM4, ASSY_XENLA ;
DR   Q5M8Z6, ASSY_XENTR ;  Q9PEM9, ASSY_XYLFA ;  P59606, ASSY_XYLFT ;
DR   P22768, ASSY_YEAST ;  A1JTL6, ASSY_YERE8 ;  A7FJE9, ASSY_YERP3 ;
DR   B2JZQ2, ASSY_YERPB ;  Q8ZFV7, ASSY_YERPE ;  A9R622, ASSY_YERPG ;
DR   Q1CGZ2, ASSY_YERPN ;  A4TKI3, ASSY_YERPP ;  Q66C31, ASSY_YERPS ;
DR   B1JPT9, ASSY_YERPY ;  Q5NNQ0, ASSY_ZYMMO ;
//
ID   6.3.4.6
DE   Urea carboxylase.
AN   ATP--urea amidolyase.
AN   UALase.
AN   UCA.
AN   Urea amidolyase.
AN   Urea carboxylase (hydrolyzing).
AN   Urease (ATP-hydrolyzing).
CA   ATP + urea + HCO(3)(-) = ADP + phosphate + urea-1-carboxylate.
CF   Biotin.
CC   -!- The Saccharomyces cerevisiae enzyme (but not that from green algae)
CC       also catalyzes the reaction of EC 3.5.1.54, thus bringing about the
CC       hydrolysis of urea to CO(2) and NH(3).
CC   -!- The enzyme from the prokaryotic bacterium Oleomonas sagaranensis can
CC       also use acetamide and formamide as substrates.
CC   -!- Formerly EC 3.5.1.45.
PR   PROSITE; PDOC00167;
PR   PROSITE; PDOC00676;
PR   PROSITE; PDOC50975;
PR   PROSITE; PDOC50979;
DR   A5H0J2, DUR1_SACKL ;  P32528, DUR1_YEAST ;  P38095, LAMA_EMENI ;
//
ID   6.3.4.7
DE   Ribose-5-phosphate--ammonia ligase.
AN   5-phosphoribosylamine synthetase.
AN   Ribose 5-phosphate aminotransferase.
CA   ATP + ribose 5-phosphate + NH(3) = ADP + phosphate +
CA   5-phosphoribosylamine.
//
ID   6.3.4.8
DE   Imidazoleacetate--phosphoribosyldiphosphate ligase.
AN   5-phosphoribosylimidazoleacetate synthetase.
CA   ATP + imidazole-4-acetate + 5-phosphoribosyl diphosphate = ADP +
CA   phosphate + 1-(5-phosphoribosyl)imidazole-4-acetate + diphosphate.
//
ID   6.3.4.9
DE   Biotin--[methylmalonyl-CoA-carboxytransferase] ligase.
AN   Biotin--[methylmalonyl-CoA-carboxyltransferase] ligase.
AN   Biotin--[methylmalonyl-CoA-carboxyltransferase] synthetase.
AN   Biotin--[methylmalonyl-CoA-carboxytransferase] synthetase.
AN   Biotin-transcarboxylase synthetase.
CA   ATP + biotin + apo-[methylmalonyl-CoA:pyruvate carboxytransferase] =
CA   AMP + diphosphate + [methylmalonyl-CoA:pyruvate carboxytransferase].
DR   P50747, BPL1_HUMAN ;  Q920N2, BPL1_MOUSE ;  O14353, BPL1_SCHPO ;
DR   P48445, BPL1_YEAST ;
//
ID   6.3.4.10
DE   Biotin--[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase.
AN   Biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] synthetase.
AN   Holocarboxylase synthetase.
AN   Propionyl-CoA holocarboxylase synthetase.
CA   ATP + biotin + apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] =
CA   AMP + diphosphate + [propionyl-CoA:carbon-dioxide ligase (ADP-forming)].
DR   P50747, BPL1_HUMAN ;  Q920N2, BPL1_MOUSE ;  O14353, BPL1_SCHPO ;
DR   P48445, BPL1_YEAST ;
//
ID   6.3.4.11
DE   Biotin--[methylcrotonoyl-CoA-carboxylase] ligase.
AN   Biotin--[methylcrotonoyl-CoA-carboxylase] synthetase.
CA   ATP + biotin + apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-
CA   forming)] = AMP + diphosphate + [3-methylcrotonoyl-CoA:carbon-dioxide
CA   ligase (ADP-forming)].
DR   P50747, BPL1_HUMAN ;  Q920N2, BPL1_MOUSE ;  O14353, BPL1_SCHPO ;
DR   P48445, BPL1_YEAST ;
//
ID   6.3.4.12
DE   Glutamate--methylamine ligase.
AN   Gamma-glutamylmethylamide synthetase.
CA   ATP + L-glutamate + methylamine = ADP + phosphate + N(5)-methyl-L-
CA   glutamine.
//
ID   6.3.4.13
DE   Phosphoribosylamine--glycine ligase.
AN   GAR synthetase.
AN   GARS.
AN   Glycinamide ribonucleotide synthetase.
AN   Phosphoribosylglycinamide synthetase.
CA   ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N(1)-
CA   (5-phospho-D-ribosyl)glycinamide.
CC   -!- Formerly EC 6.3.1.3.
PR   PROSITE; PDOC00164;
PR   PROSITE; PDOC50975;
DR   Q8UHN3, PUR2_AGRT5 ;  Q46482, PUR2_ALLVD ;  O66949, PUR2_AQUAE ;
DR   P52420, PUR2_ARATH ;  O29108, PUR2_ARCFU ;  Q9KF52, PUR2_BACHD ;
DR   P12039, PUR2_BACSU ;  Q59A32, PUR2_BOVIN ;  Q8YFK1, PUR2_BRUME ;
DR   Q8G2B1, PUR2_BRUSU ;  Q9PN47, PUR2_CAMJE ;  Q5HTL1, PUR2_CAMJR ;
DR   Q9ABD2, PUR2_CAUCR ;  P21872, PUR2_CHICK ;  Q26255, PUR2_CHITE ;
DR   Q8KBV8, PUR2_CHLTE ;  Q97J90, PUR2_CLOAB ;  Q9RHX4, PUR2_CORAM ;
DR   Q8NMH3, PUR2_CORGL ;  Q9RUF5, PUR2_DEIRA ;  Q54GJ2, PUR2_DICDI ;
DR   P00967, PUR2_DROME ;  P16340, PUR2_DROPS ;  Q8X612, PUR2_ECO57 ;
DR   Q8FB69, PUR2_ECOL6 ;  P15640, PUR2_ECOLI ;  Q8REV7, PUR2_FUSNN ;
DR   P43845, PUR2_HAEIN ;  Q9ZK07, PUR2_HELPJ ;  O25817, PUR2_HELPY ;
DR   P22102, PUR2_HUMAN ;  Q9ZF44, PUR2_LACLA ;  Q88U30, PUR2_LACPL ;
DR   Q6ACE6, PUR2_LEIXX ;  Q72V31, PUR2_LEPIC ;  Q8EZT7, PUR2_LEPIN ;
DR   Q92AP4, PUR2_LISIN ;  Q71YQ4, PUR2_LISMF ;  Q8Y6C6, PUR2_LISMO ;
DR   Q8TKT6, PUR2_METAC ;  A7I6J7, PUR2_METB6 ;  Q465Q9, PUR2_METBF ;
DR   Q12X37, PUR2_METBU ;  Q58347, PUR2_METJA ;  Q8TWG3, PUR2_METKA ;
DR   A2SQ86, PUR2_METLZ ;  A4FZB0, PUR2_METM5 ;  A9A6Q7, PUR2_METM6 ;
DR   A6VJ27, PUR2_METM7 ;  Q8Q0J2, PUR2_METMA ;  A3CU83, PUR2_METMJ ;
DR   Q6M079, PUR2_METMP ;  A5UMK4, PUR2_METS3 ;  Q2NI86, PUR2_METST ;
DR   O27494, PUR2_METTH ;  A6US04, PUR2_METVS ;  Q64737, PUR2_MOUSE ;
DR   P65894, PUR2_MYCBO ;  Q50144, PUR2_MYCLE ;  P65893, PUR2_MYCTU ;
DR   Q9JWU6, PUR2_NEIMA ;  Q9JXA3, PUR2_NEIMB ;  Q8YRD8, PUR2_NOSS1 ;
DR   P57829, PUR2_PASMU ;  B4REI0, PUR2_PHEZH ;  Q9HUV8, PUR2_PSEAE ;
DR   Q88DK2, PUR2_PSEPK ;  Q87VR8, PUR2_PSESM ;  Q9UY71, PUR2_PYRAB ;
DR   Q8U3N5, PUR2_PYRFU ;  O58061, PUR2_PYRHO ;  Q5JFP1, PUR2_PYRKO ;
DR   Q8XXC4, PUR2_RALSO ;  Q986A5, PUR2_RHILO ;  Q92RL0, PUR2_RHIME ;
DR   Q7UPZ8, PUR2_RHOBA ;  Q8Z334, PUR2_SALTI ;  P26977, PUR2_SALTY ;
DR   P20772, PUR2_SCHPO ;  Q5HH10, PUR2_STAAC ;  P65895, PUR2_STAAM ;
DR   P65896, PUR2_STAAN ;  Q6GI10, PUR2_STAAR ;  Q6GAD9, PUR2_STAAS ;
DR   Q8NX87, PUR2_STAAW ;  Q5HQ96, PUR2_STAEQ ;  Q8CT26, PUR2_STAES ;
DR   Q9RKL4, PUR2_STRCO ;  Q9A1Y7, PUR2_STRP1 ;  P0DD58, PUR2_STRP3 ;
DR   Q5XEF0, PUR2_STRP6 ;  Q8P308, PUR2_STRP8 ;  Q97T98, PUR2_STRPN ;
DR   P0DD59, PUR2_STRPQ ;  Q8DRM0, PUR2_STRR6 ;  Q9F1S9, PUR2_STRSU ;
DR   P74232, PUR2_SYNY3 ;  C5A4U0, PUR2_THEGJ ;  Q9X0X7, PUR2_THEMA ;
DR   Q8RC54, PUR2_THETN ;  Q0W6Q4, PUR2_UNCMA ;  Q9KV81, PUR2_VIBCH ;
DR   Q87KS8, PUR2_VIBPA ;  Q8DD07, PUR2_VIBVU ;  Q7MGT4, PUR2_VIBVY ;
DR   P52421, PUR2_VIGUN ;  Q8D245, PUR2_WIGBR ;  Q8PQ21, PUR2_XANAC ;
DR   Q8PD48, PUR2_XANCP ;  Q9PC09, PUR2_XYLFA ;  Q87D59, PUR2_XYLFT ;
DR   Q99148, PUR2_YARLI ;  P07244, PUR2_YEAST ;  Q8ZAR2, PUR2_YERPE ;
DR   Q9FDL5, PUR2_ZYMMO ;
//
ID   6.3.4.14
DE   Biotin carboxylase.
CA   ATP + biotin-[carboxyl-carrier-protein] + CO(2) = ADP + phosphate +
CA   carboxy-biotin-[carboxyl-carrier-protein].
PR   PROSITE; PDOC50975;
DR   Q9TTS3, ACACA_BOVIN;  Q13085, ACACA_HUMAN;  Q5SWU9, ACACA_MOUSE;
DR   P11497, ACACA_RAT  ;  Q28559, ACACA_SHEEP;  O00763, ACACB_HUMAN;
DR   P11029, ACAC_CHICK ;  Q54J08, ACAC_DICDI ;  P78820, ACAC_SCHPO ;
DR   Q00955, ACAC_YEAST ;  Q38970, ACC1_ARATH ;  Q8S6N5, ACC1_ORYSJ ;
DR   F4I1L3, ACC2_ARATH ;  B9FK36, ACC2_ORYSJ ;  P49787, ACCC1_BACSU;
DR   B9HBA8, ACCC1_POPTR;  O34544, ACCC2_BACSU;  B9N843, ACCC2_POPTR;
DR   O52058, ACCC_ALLVD ;  O04983, ACCC_ARATH ;  Q9KDS9, ACCC_BACHD ;
DR   Q8X9B6, ACCC_ECO57 ;  P24182, ACCC_ECOLI ;  P43873, ACCC_HAEIN ;
DR   Q06862, ACCC_NOSS1 ;  P84546, ACCC_POPEU ;  P37798, ACCC_PSEAE ;
DR   P0A509, BCCA_MYCBO ;  P46392, BCCA_MYCLE ;  P0A508, BCCA_MYCTU ;
DR   B3LM95, HFA1_YEAS1 ;  C7GRE4, HFA1_YEAS2 ;  A6ZMR9, HFA1_YEAS7 ;
DR   C8ZF72, HFA1_YEAS8 ;  P32874, HFA1_YEAST ;
//
ID   6.3.4.15
DE   Biotin--[acetyl-CoA-carboxylase] ligase.
AN   Acetyl-CoA carboxylase biotin holoenzyme synthetase.
AN   Biotin--[acetyl-CoA carboxylase] synthetase.
AN   Biotin--protein ligase.
CA   ATP + biotin + apo-[acetyl-CoA:carbon-dioxide ligase (ADP-forming)] =
CA   AMP + diphosphate + [acetyl-CoA:carbon-dioxide ligase (ADP-forming)].
DR   Q5F5C8, BICOA_NEIG1;  Q9JWI7, BICOA_NEIMA;  Q9JXF1, BICOA_NEIMB;
DR   E0U174, BIRA_BACPZ ;  P0CI75, BIRA_BACSU ;  P06709, BIRA_ECOLI ;
DR   P46363, BIRA_HAEIN ;  P29906, BIRA_PARDE ;  P37416, BIRA_SALTY ;
DR   P50747, BPL1_HUMAN ;  Q920N2, BPL1_MOUSE ;  O14353, BPL1_SCHPO ;
DR   P48445, BPL1_YEAST ;  Q59014, BPL_METJA  ;
//
ID   6.3.4.16
DE   Carbamoyl-phosphate synthase (ammonia).
AN   Carbamoyl-phosphate synthetase (ammonia).
AN   Carbamoyl-phosphate synthetase I.
AN   Carbamoylphosphate synthetase (ammonia).
AN   Carbon-dioxide--ammonia ligase.
AN   CPS I.
CA   2 ATP + NH(3) + CO(2) + H(2)O = 2 ADP + phosphate + carbamoyl phosphate.
CC   -!- Formerly EC 2.7.2.5.
PR   PROSITE; PDOC00676;
DR   P31327, CPSM_HUMAN ;  Q8C196, CPSM_MOUSE ;  Q91293, CPSM_RANCA ;
DR   P07756, CPSM_RAT   ;
//
ID   6.3.4.17
DE   Formate--dihydrofolate ligase.
AN   Dihydrofolate formyltransferase.
AN   Formyl dihydrofolate synthase.
CA   ATP + formate + dihydrofolate = ADP + phosphate + 10-formyldihydrofolate.
//
ID   6.3.4.18
DE   5-(carboxyamino)imidazole ribonucleotide synthase.
AN   N(5)-CAIR synthetase.
AN   N(5)-carboxyaminoimidazole ribonucleotide synthetase.
CA   ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole + HCO(3)(-) = ADP +
CA   phosphate + 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole.
CC   -!- In Escherichia coli, this enzyme, along with EC 5.4.99.18,
CC       is required to carry out the single reaction catalyzed by EC 4.1.1.21
CC       in vertebrates.
CC   -!- Carboxyphosphate is the putative acyl phosphate intermediate.
CC   -!- Involved in the late stages of purine biosynthesis.
DR   O66608, PURK_AQUAE ;  P12045, PURK_BACSU ;  P52559, PURK_BRUME ;
DR   Q44678, PURK_CORAM ;  P09029, PURK_ECOLI ;  P43850, PURK_HAEIN ;
DR   P65899, PURK_MYCBO ;  P46701, PURK_MYCLE ;  P65898, PURK_MYCTU ;
DR   P72158, PURK_PSEAE ;  Q5HH19, PURK_STAAC ;  Q99V32, PURK_STAAM ;
DR   Q7A695, PURK_STAAN ;  Q6GI19, PURK_STAAR ;  Q6GAE8, PURK_STAAS ;
DR   Q8NX94, PURK_STAAW ;  Q5HQA5, PURK_STAEQ ;  Q8CPP2, PURK_STAES ;
DR   Q4L574, PURK_STAHJ ;  Q49WI9, PURK_STAS1 ;  O06457, PURK_SULSO ;
DR   Q54975, PURK_SYNE7 ;  P74724, PURK_SYNY3 ;  Q9KVT8, PURK_VIBCH ;
DR   Q5E1R3, PURK_VIBF1 ;  Q87KE0, PURK_VIBPA ;  Q8DDD8, PURK_VIBVU ;
DR   Q7MGL1, PURK_VIBVY ;
//
ID   6.3.5.1
DE   NAD(+) synthase (glutamine-hydrolyzing).
AN   NAD(+) synthetase (glutamine-hydrolyzing).
AN   Nicotinamide adenine dinucleotide synthetase (glutamine).
CA   ATP + deamido-NAD(+) + L-glutamine + H(2)O = AMP + diphosphate + NAD(+) +
CA   L-glutamate.
CC   -!- NH(3) can act instead of glutamine (cf. EC 6.3.1.5).
PR   PROSITE; PDOC50263;
DR   Q9X0Y0, NADE2_THEMA;  O67091, NADE_AQUAE ;  Q3ZBF0, NADE_BOVIN ;
DR   Q5ZMA6, NADE_CHICK ;  Q54ML1, NADE_DICDI ;  Q9VYA0, NADE_DROME ;
DR   Q6IA69, NADE_HUMAN ;  Q4R5Y2, NADE_MACFA ;  Q711T7, NADE_MOUSE ;
DR   P0A5L7, NADE_MYCBO ;  Q9CBZ6, NADE_MYCLE ;  P0A5L6, NADE_MYCTU ;
DR   Q812E8, NADE_RAT   ;  Q03638, NADE_RHOCA ;  O74940, NADE_SCHPO ;
DR   P74292, NADE_SYNY3 ;  O83759, NADE_TREPA ;  Q9PC24, NADE_XYLFA ;
DR   Q87D47, NADE_XYLFT ;  P38795, NADE_YEAST ;
//
ID   6.3.5.2
DE   GMP synthase (glutamine-hydrolyzing).
AN   Glutamine amidotransferase.
AN   GMP synthetase (glutamine-hydrolyzing).
CA   ATP + xanthosine 5'-phosphate + L-glutamine + H(2)O = AMP + diphosphate +
CA   GMP + L-glutamate.
PR   PROSITE; PDOC00405;
DR   Q89ZV6, GUAA1_BACTN;  Q8A525, GUAA2_BACTN;  O28949, GUAAA_ARCFU;
DR   Q5V1K0, GUAAA_HALMA;  Q9HSH4, GUAAA_HALSA;  Q18KM8, GUAAA_HALWD;
DR   A8AC69, GUAAA_IGNH4;  A6UVC9, GUAAA_META3;  Q8THC7, GUAAA_METAC;
DR   A7I661, GUAAA_METB6;  Q46E00, GUAAA_METBF;  Q12UJ5, GUAAA_METBU;
DR   Q2FL30, GUAAA_METHJ;  Q58970, GUAAA_METJA;  Q8TXV8, GUAAA_METKA;
DR   A4FW79, GUAAA_METM5;  A9A9L8, GUAAA_METM6;  A6VH31, GUAAA_METM7;
DR   Q8PXF0, GUAAA_METMA;  A3CTG9, GUAAA_METMJ;  Q6LXA7, GUAAA_METMP;
DR   A5UK20, GUAAA_METS3;  Q2NER5, GUAAA_METST;  O26805, GUAAA_METTH;
DR   A0B5J1, GUAAA_METTP;  A6UQ90, GUAAA_METVS;  Q3ITY2, GUAAA_NATPD;
DR   Q6KZC5, GUAAA_PICTO;  Q9V0I6, GUAAA_PYRAB;  Q8U0R9, GUAAA_PYRFU;
DR   O59071, GUAAA_PYRHO;  Q5JFM4, GUAAA_PYRKO;  Q8X239, GUAAA_SULAC;
DR   Q97VZ9, GUAAA_SULSO;  Q974T4, GUAAA_SULTO;  Q9HJM3, GUAAA_THEAC;
DR   Q979P8, GUAAA_THEVO;  Q0W700, GUAAA_UNCMA;  O29986, GUAAB_ARCFU;
DR   B9LTX1, GUAAB_HALLT;  Q5UX56, GUAAB_HALMA;  B0R6G1, GUAAB_HALS3;
DR   Q9HP33, GUAAB_HALSA;  Q8THK3, GUAAB_METAC;  A7IA92, GUAAB_METB6;
DR   Q46D96, GUAAB_METBF;  Q12ZP6, GUAAB_METBU;  Q58531, GUAAB_METJA;
DR   Q8TYD7, GUAAB_METKA;  A6VFI6, GUAAB_METM7;  Q8PXK0, GUAAB_METMA;
DR   A3CWS6, GUAAB_METMJ;  Q6LYU3, GUAAB_METMP;  B8GIB2, GUAAB_METPE;
DR   O26806, GUAAB_METTH;  A6UN70, GUAAB_METVS;  Q3IS14, GUAAB_NATPD;
DR   Q6L1Q1, GUAAB_PICTO;  Q9V0I7, GUAAB_PYRAB;  Q8U0R8, GUAAB_PYRFU;
DR   O59072, GUAAB_PYRHO;  Q5JFM1, GUAAB_PYRKO;  C3N0R9, GUAAB_SULIA;
DR   C4KJU6, GUAAB_SULIK;  C3MJX9, GUAAB_SULIL;  C3MRT0, GUAAB_SULIM;
DR   C3NMG4, GUAAB_SULIN;  C3N905, GUAAB_SULIY;  Q97TZ8, GUAAB_SULSO;
DR   Q96Y23, GUAAB_SULTO;  Q9HIH8, GUAAB_THEAC;  Q97C09, GUAAB_THEVO;
DR   Q0W468, GUAAB_UNCMA;  Q6FFN2, GUAA_ACIAD ;  A3MZV8, GUAA_ACTP2 ;
DR   B3H120, GUAA_ACTP7 ;  B0BUF0, GUAA_ACTPJ ;  A6VMR9, GUAA_ACTSZ ;
DR   A0KJS0, GUAA_AERHH ;  Q9Y933, GUAA_AERPE ;  A4SM23, GUAA_AERS4 ;
DR   B9J7L1, GUAA_AGRRK ;  Q8UIL2, GUAA_AGRT5 ;  B9JZA3, GUAA_AGRVS ;
DR   Q0VNF0, GUAA_ALCBS ;  Q0A9W8, GUAA_ALHEH ;  B6EGZ6, GUAA_ALISL ;
DR   A6TLR3, GUAA_ALKMQ ;  B4RV80, GUAA_ALTMD ;  B9KH18, GUAA_ANAMF ;
DR   Q5P9L5, GUAA_ANAMM ;  B9MS76, GUAA_ANATD ;  Q3MEA8, GUAA_ANAVT ;
DR   O66601, GUAA_AQUAE ;  A8ETA7, GUAA_ARCB4 ;  Q5NYE5, GUAA_AROAE ;
DR   Q756B7, GUAA_ASHGO ;  Q4WFT3, GUAA_ASPFU ;  Q2UFN0, GUAA_ASPOR ;
DR   A1K5U3, GUAA_AZOSB ;  A7Z235, GUAA_BACA2 ;  C3PBL1, GUAA_BACAA ;
DR   C3L508, GUAA_BACAC ;  A0R8W7, GUAA_BACAH ;  Q81VE0, GUAA_BACAN ;
DR   B7JM61, GUAA_BACC0 ;  Q73ER7, GUAA_BACC1 ;  B7IUT1, GUAA_BACC2 ;
DR   C1EUB4, GUAA_BACC3 ;  B7H4Q8, GUAA_BACC4 ;  A7GKG1, GUAA_BACCN ;
DR   Q81IS3, GUAA_BACCR ;  Q63GV4, GUAA_BACCZ ;  Q5LGV6, GUAA_BACFN ;
DR   Q64XQ7, GUAA_BACFR ;  Q9KF78, GUAA_BACHD ;  Q6HPC6, GUAA_BACHK ;
DR   Q65MU0, GUAA_BACLD ;  A8FAH5, GUAA_BACP2 ;  Q5WJI0, GUAA_BACSK ;
DR   P29727, GUAA_BACSU ;  A6L686, GUAA_BACV8 ;  A9VQG9, GUAA_BACWK ;
DR   A1URR0, GUAA_BARBK ;  Q6G5J3, GUAA_BARHE ;  Q6G197, GUAA_BARQU ;
DR   Q1LSJ1, GUAA_BAUCH ;  Q6MLD2, GUAA_BDEBA ;  Q8G5P4, GUAA_BIFLO ;
DR   Q7VRS2, GUAA_BLOFL ;  Q492E5, GUAA_BLOPB ;  Q2L1U0, GUAA_BORA1 ;
DR   E4QHI6, GUAA_BORBN ;  Q7WK13, GUAA_BORBR ;  P0CL64, GUAA_BORBU ;
DR   Q6ASN4, GUAA_BORGA ;  Q7WAV6, GUAA_BORPA ;  A9IKK0, GUAA_BORPD ;
DR   Q7VVM4, GUAA_BORPE ;  C0QYF1, GUAA_BRAHW ;  Q89N53, GUAA_BRAJA ;
DR   A4YSU1, GUAA_BRASO ;  B2SBN5, GUAA_BRUA1 ;  Q2YK38, GUAA_BRUA2 ;
DR   Q577H0, GUAA_BRUAB ;  A9MEB0, GUAA_BRUC2 ;  C0RKS9, GUAA_BRUMB ;
DR   Q8YBL2, GUAA_BRUME ;  A5VU71, GUAA_BRUO2 ;  A9WY54, GUAA_BRUSI ;
DR   Q8FWT4, GUAA_BRUSU ;  B1YS44, GUAA_BURA4 ;  Q1BHF2, GUAA_BURCA ;
DR   B1JUC0, GUAA_BURCC ;  A0K8B3, GUAA_BURCH ;  B4EC68, GUAA_BURCJ ;
DR   Q0BE45, GUAA_BURCM ;  A9AIP4, GUAA_BURM1 ;  A3MKQ7, GUAA_BURM7 ;
DR   A2SBA7, GUAA_BURM9 ;  Q62JF6, GUAA_BURMA ;  A1V534, GUAA_BURMS ;
DR   A3NWJ3, GUAA_BURP0 ;  Q3JR65, GUAA_BURP1 ;  A3NAR3, GUAA_BURP6 ;
DR   B2JIA0, GUAA_BURP8 ;  B2T5G8, GUAA_BURPP ;  Q63T42, GUAA_BURPS ;
DR   Q39F73, GUAA_BURS3 ;  A4JF45, GUAA_BURVG ;  Q13XE2, GUAA_BURXL ;
DR   Q09580, GUAA_CAEEL ;  A4XKX8, GUAA_CALS8 ;  A0RQD7, GUAA_CAMFF ;
DR   A7I131, GUAA_CAMHC ;  A8FMV3, GUAA_CAMJ8 ;  A7H2D2, GUAA_CAMJD ;
DR   Q9PN49, GUAA_CAMJE ;  A1W0N3, GUAA_CAMJJ ;  Q5HTL3, GUAA_CAMJR ;
DR   B9KFL4, GUAA_CAMLR ;  Q5APF2, GUAA_CANAL ;  Q6FUF3, GUAA_CANGA ;
DR   Q3AD70, GUAA_CARHZ ;  B8GVI7, GUAA_CAUCN ;  Q9A7U9, GUAA_CAUCR ;
DR   B3PIG3, GUAA_CELJU ;  Q3AT13, GUAA_CHLCH ;  Q822V6, GUAA_CHLCV ;
DR   Q254T8, GUAA_CHLFF ;  B3EEV3, GUAA_CHLL2 ;  Q9PKM3, GUAA_CHLMU ;
DR   B3ELI1, GUAA_CHLPB ;  A1BD85, GUAA_CHLPD ;  Q9Z913, GUAA_CHLPN ;
DR   B3QYF4, GUAA_CHLT3 ;  Q8KFZ5, GUAA_CHLTE ;  Q7NSG1, GUAA_CHRVO ;
DR   A8AD80, GUAA_CITK8 ;  Q97FM9, GUAA_CLOAB ;  A7FYP0, GUAA_CLOB1 ;
DR   C3KUC5, GUAA_CLOB6 ;  A6LQ90, GUAA_CLOB8 ;  B2UZ05, GUAA_CLOBA ;
DR   B2TIX3, GUAA_CLOBB ;  A5I720, GUAA_CLOBH ;  C1FLV2, GUAA_CLOBJ ;
DR   B1IFD1, GUAA_CLOBK ;  A7GIN0, GUAA_CLOBL ;  B1L1J7, GUAA_CLOBM ;
DR   B8I4P0, GUAA_CLOCE ;  Q18CT8, GUAA_CLOD6 ;  B9DYY7, GUAA_CLOK1 ;
DR   A5N5D9, GUAA_CLOK5 ;  A0Q2S8, GUAA_CLONN ;  Q8XI46, GUAA_CLOPE ;
DR   Q891G7, GUAA_CLOTE ;  A3DCD4, GUAA_CLOTH ;  Q47WD1, GUAA_COLP3 ;
DR   O52831, GUAA_CORAM ;  P60499, GUAA_CORDI ;  Q8FRZ3, GUAA_COREF ;
DR   A4QBV0, GUAA_CORGB ;  Q8NSR1, GUAA_CORGL ;  Q4JTG0, GUAA_CORJK ;
DR   B6J7Z4, GUAA_COXB1 ;  B6IZE2, GUAA_COXB2 ;  A9KGD5, GUAA_COXBN ;
DR   A9N8L6, GUAA_COXBR ;  Q83BZ6, GUAA_COXBU ;  Q0KA43, GUAA_CUPNH ;
DR   Q470G4, GUAA_CUPPJ ;  B3R290, GUAA_CUPTR ;  B1WY30, GUAA_CYAA5 ;
DR   B7K8T7, GUAA_CYAP7 ;  B7JXM2, GUAA_CYAP8 ;  Q11WK3, GUAA_CYTH3 ;
DR   Q6BLS3, GUAA_DEBHA ;  Q47DK8, GUAA_DECAR ;  Q3Z886, GUAA_DEHE1 ;
DR   Q3ZXH7, GUAA_DEHSC ;  C1D0M2, GUAA_DEIDV ;  Q1J0T4, GUAA_DEIGD ;
DR   Q9RT91, GUAA_DEIRA ;  C6BSD8, GUAA_DESAD ;  Q311X7, GUAA_DESDG ;
DR   C4XSN8, GUAA_DESMR ;  Q6APU2, GUAA_DESPS ;  Q72D86, GUAA_DESVH ;
DR   B8DNB9, GUAA_DESVM ;  A1VEV0, GUAA_DESVV ;  P32073, GUAA_DICDI ;
DR   A8LKW5, GUAA_DINSH ;  A7ZPV1, GUAA_ECO24 ;  B7UGU5, GUAA_ECO27 ;
DR   B7MHY8, GUAA_ECO45 ;  B7LCP7, GUAA_ECO55 ;  P64295, GUAA_ECO57 ;
DR   B5Z0X6, GUAA_ECO5E ;  B7NQV3, GUAA_ECO7I ;  B7MYD5, GUAA_ECO81 ;
DR   B7M7L1, GUAA_ECO8A ;  C4ZX82, GUAA_ECOBW ;  B1XAY2, GUAA_ECODH ;
DR   A8A313, GUAA_ECOHS ;  A1AE43, GUAA_ECOK1 ;  Q0TEY1, GUAA_ECOL5 ;
DR   P64294, GUAA_ECOL6 ;  B1IWF4, GUAA_ECOLC ;  P04079, GUAA_ECOLI ;
DR   B7N691, GUAA_ECOLU ;  B6I579, GUAA_ECOSE ;  B1LNF9, GUAA_ECOSM ;
DR   Q1R8M9, GUAA_ECOUT ;  C5BER5, GUAA_EDWI9 ;  Q3YT30, GUAA_EHRCJ ;
DR   Q2GHY2, GUAA_EHRCR ;  Q5FF75, GUAA_EHRRG ;  Q5HCA2, GUAA_EHRRW ;
DR   B2KCS8, GUAA_ELUMP ;  Q5B1L4, GUAA_EMENI ;  A4WD82, GUAA_ENT38 ;
DR   Q839J8, GUAA_ENTFA ;  A7MGU1, GUAA_ENTS8 ;  Q6D288, GUAA_ERWCT ;
DR   B7LKD4, GUAA_ESCF3 ;  C4Z3X1, GUAA_EUBE2 ;  C4ZCQ4, GUAA_EUBR3 ;
DR   B1YIZ1, GUAA_EXIS2 ;  B0S0S7, GUAA_FINM2 ;  A5FHB4, GUAA_FLAJ1 ;
DR   A6H0T6, GUAA_FLAPJ ;  B0U0B2, GUAA_FRAP2 ;  A8LAX2, GUAA_FRASN ;
DR   Q14HJ0, GUAA_FRAT1 ;  A7NCA3, GUAA_FRATF ;  Q2A3D4, GUAA_FRATH ;
DR   B2SGK4, GUAA_FRATM ;  A0Q6C0, GUAA_FRATN ;  Q0BLV0, GUAA_FRATO ;
DR   Q5NG38, GUAA_FRATT ;  A4IXW6, GUAA_FRATW ;  Q8RDR4, GUAA_FUSNN ;
DR   C1A3W7, GUAA_GEMAT ;  Q5L3E1, GUAA_GEOKA ;  Q39TA7, GUAA_GEOMG ;
DR   B9M9G4, GUAA_GEOSF ;  P60500, GUAA_GEOSL ;  Q4HXF0, GUAA_GIBZE ;
DR   Q7NHC2, GUAA_GLOVI ;  Q5FPL0, GUAA_GLUOX ;  A0M3J8, GUAA_GRAFK ;
DR   Q7VLE9, GUAA_HAEDU ;  Q4QNW4, GUAA_HAEI8 ;  A5UAR3, GUAA_HAEIE ;
DR   A5UG27, GUAA_HAEIG ;  P44335, GUAA_HAEIN ;  B8F3T2, GUAA_HAEPS ;
DR   Q0I2D2, GUAA_HAES1 ;  B0USI5, GUAA_HAES2 ;  Q2SCJ3, GUAA_HAHCH ;
DR   B8D0Z5, GUAA_HALOH ;  C4K7H1, GUAA_HAMD5 ;  Q17YH9, GUAA_HELAH ;
DR   Q7VG78, GUAA_HELHP ;  B0TI09, GUAA_HELMI ;  B6JMN5, GUAA_HELP2 ;
DR   B5Z842, GUAA_HELPG ;  Q1CSM2, GUAA_HELPH ;  Q9ZKG4, GUAA_HELPJ ;
DR   B2UUF1, GUAA_HELPS ;  O25165, GUAA_HELPY ;  A4G4U7, GUAA_HERAR ;
DR   P49915, GUAA_HUMAN ;  Q5QWW5, GUAA_IDILO ;  A6SZM5, GUAA_JANMA ;
DR   B5XNM4, GUAA_KLEP3 ;  A6TCC2, GUAA_KLEP7 ;  Q6CU71, GUAA_KLULA ;
DR   Q5FMD6, GUAA_LACAC ;  Q036Y5, GUAA_LACC3 ;  B3W952, GUAA_LACCB ;
DR   Q1GBU7, GUAA_LACDA ;  Q04CA4, GUAA_LACDB ;  Q046I2, GUAA_LACGA ;
DR   Q74LF7, GUAA_LACJO ;  Q9CFJ0, GUAA_LACLA ;  Q9Z6H4, GUAA_LACLM ;
DR   Q02Y87, GUAA_LACLS ;  Q88Y74, GUAA_LACPL ;  A5VLY3, GUAA_LACRD ;
DR   O85192, GUAA_LACRH ;  B2G994, GUAA_LACRJ ;  Q1WRY8, GUAA_LACS1 ;
DR   P83540, GUAA_LACSN ;  Q38ZE1, GUAA_LACSS ;  Q5X4I9, GUAA_LEGPA ;
DR   A5ICM2, GUAA_LEGPC ;  Q5ZUS0, GUAA_LEGPH ;  Q5WVX4, GUAA_LEGPL ;
DR   Q6AD51, GUAA_LEIXX ;  Q72RB7, GUAA_LEPIC ;  Q8F4F4, GUAA_LEPIN ;
DR   Q92CU0, GUAA_LISIN ;  Q720X7, GUAA_LISMF ;  Q8Y822, GUAA_LISMO ;
DR   A0AHK7, GUAA_LISW6 ;  B9E8Y0, GUAA_MACCJ ;  Q65UI1, GUAA_MANSM ;
DR   A1U1E2, GUAA_MARAV ;  A6W2W4, GUAA_MARMS ;  Q6F1C4, GUAA_MESFL ;
DR   Q60C21, GUAA_METCA ;  Q1H280, GUAA_METFK ;  A2SG95, GUAA_METPP ;
DR   C5CBZ4, GUAA_MICLC ;  Q2RGP2, GUAA_MOOTA ;  Q3THK7, GUAA_MOUSE ;
DR   P0A5A2, GUAA_MYCBO ;  A1KP87, GUAA_MYCBP ;  C1AHL0, GUAA_MYCBT ;
DR   B8ZUE2, GUAA_MYCLB ;  P46810, GUAA_MYCLE ;  B2HDP0, GUAA_MYCMM ;
DR   Q73U79, GUAA_MYCPA ;  Q8EWS9, GUAA_MYCPE ;  A5U871, GUAA_MYCTA ;
DR   P0A5A1, GUAA_MYCTU ;  B2A5V5, GUAA_NATTJ ;  Q5F4X9, GUAA_NEIG1 ;
DR   B4RJH7, GUAA_NEIG2 ;  A9M138, GUAA_NEIM0 ;  Q9JW60, GUAA_NEIMA ;
DR   Q9JXR2, GUAA_NEIMB ;  A1KRY5, GUAA_NEIMF ;  Q0ADW4, GUAA_NITEC ;
DR   Q82XZ6, GUAA_NITEU ;  Q1QKC3, GUAA_NITHX ;  Q2Y9R9, GUAA_NITMU ;
DR   Q3JDG3, GUAA_NITOC ;  A6Q4N8, GUAA_NITSB ;  Q3SQP4, GUAA_NITWN ;
DR   Q5Z1E9, GUAA_NOCFA ;  B2J9G3, GUAA_NOSP7 ;  Q8YT80, GUAA_NOSS1 ;
DR   Q8CXK8, GUAA_OCEIH ;  B6JHM4, GUAA_OLICO ;  B1ZNB4, GUAA_OPITP ;
DR   A6LD04, GUAA_PARD8 ;  Q9CNX8, GUAA_PASMU ;  C6DBG3, GUAA_PECCP ;
DR   Q03H14, GUAA_PEDPA ;  Q3A590, GUAA_PELCD ;  Q3B1J3, GUAA_PELLD ;
DR   B4SFX7, GUAA_PELPB ;  A1AQJ8, GUAA_PELPD ;  Q4FMW8, GUAA_PELUB ;
DR   A9BER7, GUAA_PETMO ;  Q0UHC4, GUAA_PHANO ;  B4R9R7, GUAA_PHEZH ;
DR   Q7N3K4, GUAA_PHOLL ;  Q6LU31, GUAA_PHOPR ;  B1XTW6, GUAA_POLNS ;
DR   A4SYS2, GUAA_POLSQ ;  Q5RA96, GUAA_PONAB ;  B2RIF9, GUAA_PORG3 ;
DR   Q7MWL9, GUAA_PORGI ;  Q6A6X1, GUAA_PROAC ;  A3PA84, GUAA_PROM0 ;
DR   A2BZD9, GUAA_PROM1 ;  A8G223, GUAA_PROM2 ;  A2C5P2, GUAA_PROM3 ;
DR   A2BTY4, GUAA_PROM5 ;  Q31DE7, GUAA_PROM9 ;  Q7VEH5, GUAA_PROMA ;
DR   B4EY59, GUAA_PROMH ;  Q7V9A9, GUAA_PROMM ;  Q7V3N7, GUAA_PROMP ;
DR   A2BNG3, GUAA_PROMS ;  Q46I26, GUAA_PROMT ;  A4SGJ0, GUAA_PROVI ;
DR   Q48LY0, GUAA_PSE14 ;  Q15R63, GUAA_PSEA6 ;  B7UXJ9, GUAA_PSEA8 ;
DR   Q02RS2, GUAA_PSEAB ;  Q9HXM6, GUAA_PSEAE ;  Q1I5K9, GUAA_PSEE4 ;
DR   Q4K6W4, GUAA_PSEF5 ;  C3K1K0, GUAA_PSEFS ;  Q3IHJ1, GUAA_PSEHT ;
DR   A4XY17, GUAA_PSEMY ;  A5VZC3, GUAA_PSEP1 ;  Q3K7D0, GUAA_PSEPF ;
DR   B0KRE6, GUAA_PSEPG ;  Q88P21, GUAA_PSEPK ;  B1JDH6, GUAA_PSEPW ;
DR   Q886X5, GUAA_PSESM ;  Q4ZX09, GUAA_PSEU2 ;  Q4FVS5, GUAA_PSYA2 ;
DR   A1SYT6, GUAA_PSYIN ;  Q8ZT92, GUAA_PYRAE ;  Q1LND0, GUAA_RALME ;
DR   B2UBD1, GUAA_RALPJ ;  Q8XZG4, GUAA_RALSO ;  Q4V7C6, GUAA_RAT   ;
DR   B3PYH7, GUAA_RHIE6 ;  Q2KDG7, GUAA_RHIEC ;  Q1MMJ7, GUAA_RHIL3 ;
DR   Q987R3, GUAA_RHILO ;  B5ZYE9, GUAA_RHILW ;  Q92SQ3, GUAA_RHIME ;
DR   C3MCS5, GUAA_RHISN ;  Q7UFS3, GUAA_RHOBA ;  Q21W48, GUAA_RHOFD ;
DR   Q2IV75, GUAA_RHOP2 ;  P60501, GUAA_RHOPA ;  Q212S9, GUAA_RHOPB ;
DR   Q2RXI5, GUAA_RHORT ;  A3PK79, GUAA_RHOS1 ;  Q3J210, GUAA_RHOS4 ;
DR   A4WTP4, GUAA_RHOS5 ;  B9KT27, GUAA_RHOSK ;  Q165N4, GUAA_ROSDO ;
DR   A1AXH0, GUAA_RUTMC ;  B5F185, GUAA_SALA4 ;  A9MHM5, GUAA_SALAR ;
DR   Q57LJ8, GUAA_SALCH ;  B5FR52, GUAA_SALDC ;  B5R569, GUAA_SALEP ;
DR   B5RCX9, GUAA_SALG2 ;  B4TD82, GUAA_SALHS ;  B4T0N7, GUAA_SALNS ;
DR   Q5PI52, GUAA_SALPA ;  A9N218, GUAA_SALPB ;  C0PYP4, GUAA_SALPC ;
DR   B5BAZ5, GUAA_SALPK ;  Q2S0V0, GUAA_SALRD ;  B4TR83, GUAA_SALSV ;
DR   Q8Z4Q3, GUAA_SALTI ;  Q8ZN60, GUAA_SALTY ;  Q9P772, GUAA_SCHPO ;
DR   A8GHV1, GUAA_SERP5 ;  A1S856, GUAA_SHEAM ;  B8E9T4, GUAA_SHEB2 ;
DR   A3D6V2, GUAA_SHEB5 ;  A6WQP0, GUAA_SHEB8 ;  A9KWW6, GUAA_SHEB9 ;
DR   Q12PS0, GUAA_SHEDO ;  Q085S4, GUAA_SHEFN ;  B0TLJ4, GUAA_SHEHH ;
DR   A3QCH0, GUAA_SHELP ;  Q8EC52, GUAA_SHEON ;  A8H254, GUAA_SHEPA ;
DR   A4Y8T3, GUAA_SHEPC ;  B8CKS4, GUAA_SHEPW ;  A0KUK2, GUAA_SHESA ;
DR   A8FY04, GUAA_SHESH ;  Q0HKV2, GUAA_SHESM ;  Q0HX50, GUAA_SHESR ;
DR   A1RHR0, GUAA_SHESW ;  B1KLC1, GUAA_SHEWM ;  B2TXT2, GUAA_SHIB3 ;
DR   Q31XY3, GUAA_SHIBS ;  Q32D55, GUAA_SHIDS ;  Q0T212, GUAA_SHIF8 ;
DR   Q83QL1, GUAA_SHIFL ;  Q3YZ45, GUAA_SHISS ;  Q5LRL6, GUAA_SILPO ;
DR   Q1GGV8, GUAA_SILST ;  A6UFA3, GUAA_SINMW ;  Q2NS52, GUAA_SODGM ;
DR   P60502, GUAA_SPIKU ;  A7WY93, GUAA_STAA1 ;  A6TYP2, GUAA_STAA2 ;
DR   Q2FJM5, GUAA_STAA3 ;  Q2G0Y6, GUAA_STAA8 ;  A5IPX0, GUAA_STAA9 ;
DR   Q2YVL5, GUAA_STAAB ;  Q5HIQ6, GUAA_STAAC ;  A6QE71, GUAA_STAAE ;
DR   P64296, GUAA_STAAM ;  P99105, GUAA_STAAN ;  Q6GJQ6, GUAA_STAAR ;
DR   Q6GC81, GUAA_STAAS ;  A8Z0R1, GUAA_STAAT ;  Q8NY69, GUAA_STAAW ;
DR   B9DLM7, GUAA_STACT ;  Q5HRX1, GUAA_STAEQ ;  Q8CMQ8, GUAA_STAES ;
DR   Q4L386, GUAA_STAHJ ;  Q49UU9, GUAA_STAS1 ;  Q3K1C0, GUAA_STRA1 ;
DR   Q8E5M8, GUAA_STRA3 ;  Q8DZX7, GUAA_STRA5 ;  Q82HM9, GUAA_STRAW ;
DR   Q9L0H2, GUAA_STRCO ;  C0MAM2, GUAA_STRE4 ;  B4SSX7, GUAA_STRM5 ;
DR   B2FNS1, GUAA_STRMK ;  Q8DU81, GUAA_STRMU ;  P64299, GUAA_STRP1 ;
DR   Q04JQ8, GUAA_STRP2 ;  P0DB54, GUAA_STRP3 ;  B5E5U0, GUAA_STRP4 ;
DR   Q5XC20, GUAA_STRP6 ;  C1C842, GUAA_STRP7 ;  P64300, GUAA_STRP8 ;
DR   Q1JBM8, GUAA_STRPB ;  Q1JLL1, GUAA_STRPC ;  Q1JGP6, GUAA_STRPD ;
DR   Q1J6G5, GUAA_STRPF ;  A2RED2, GUAA_STRPG ;  B1ICM9, GUAA_STRPI ;
DR   B8ZKZ5, GUAA_STRPJ ;  Q48TF6, GUAA_STRPM ;  P64297, GUAA_STRPN ;
DR   P0DB55, GUAA_STRPQ ;  B2IQR1, GUAA_STRPS ;  B5XLN9, GUAA_STRPZ ;
DR   P64298, GUAA_STRR6 ;  C0MFC7, GUAA_STRS7 ;  Q5M029, GUAA_STRT1 ;
DR   Q5M4P4, GUAA_STRT2 ;  B9DUB2, GUAA_STRU0 ;  C1CF29, GUAA_STRZJ ;
DR   C1CLE8, GUAA_STRZP ;  C1CQS0, GUAA_STRZT ;  Q30TH8, GUAA_SULDN ;
DR   A6QBI5, GUAA_SULNB ;  Q67S57, GUAA_SYMTH ;  B1XLR5, GUAA_SYNP2 ;
DR   Q5N2F8, GUAA_SYNP6 ;  Q7UA53, GUAA_SYNPX ;  Q0IE37, GUAA_SYNS3 ;
DR   Q3B0W1, GUAA_SYNS9 ;  Q3ANK7, GUAA_SYNSC ;  Q0AW22, GUAA_SYNWW ;
DR   P49057, GUAA_SYNY3 ;  C5BLU3, GUAA_TERTT ;  B7IHI2, GUAA_THEAB ;
DR   Q8DGA5, GUAA_THEEB ;  Q47LQ0, GUAA_THEFY ;  A6LKY1, GUAA_THEM4 ;
DR   Q9X2E0, GUAA_THEMA ;  A5ILP6, GUAA_THEP1 ;  B9L0W3, GUAA_THERP ;
DR   B1LAK3, GUAA_THESQ ;  Q72IE5, GUAA_THET2 ;  Q5SI28, GUAA_THET8 ;
DR   Q8RC63, GUAA_THETN ;  Q31F66, GUAA_THICR ;  Q3SI29, GUAA_THIDA ;
DR   C4L8C4, GUAA_TOLAT ;  Q73LZ4, GUAA_TREDE ;  Q83ID3, GUAA_TROW8 ;
DR   Q83GZ6, GUAA_TROWT ;  Q4P763, GUAA_USTMA ;  A5CVV4, GUAA_VESOH ;
DR   A5F3F1, GUAA_VIBC3 ;  Q9KTW2, GUAA_VIBCH ;  C3LT21, GUAA_VIBCM ;
DR   Q5E763, GUAA_VIBF1 ;  B5FAY1, GUAA_VIBFM ;  A7MU26, GUAA_VIBHB ;
DR   Q87S07, GUAA_VIBPA ;  B7VJU8, GUAA_VIBSL ;  Q8DF07, GUAA_VIBVU ;
DR   Q7MNE1, GUAA_VIBVY ;  Q8D1V0, GUAA_WIGBR ;  Q73IH1, GUAA_WOLPM ;
DR   B3CPU7, GUAA_WOLPP ;  Q7M8K2, GUAA_WOLSU ;  Q5GSJ3, GUAA_WOLTR ;
DR   C0R5H8, GUAA_WOLWR ;  Q8PK88, GUAA_XANAC ;  Q3BSP7, GUAA_XANC5 ;
DR   Q4UVC5, GUAA_XANC8 ;  B0RSB6, GUAA_XANCB ;  Q8P8Q6, GUAA_XANCP ;
DR   Q2P3Q9, GUAA_XANOM ;  B2SLG1, GUAA_XANOP ;  Q5H0S2, GUAA_XANOR ;
DR   B2I6W2, GUAA_XYLF2 ;  Q9PAR6, GUAA_XYLFA ;  B0U3R8, GUAA_XYLFM ;
DR   Q87BK6, GUAA_XYLFT ;  Q6CEF3, GUAA_YARLI ;  P38625, GUAA_YEAST ;
DR   A1JKT2, GUAA_YERE8 ;  A7FFZ9, GUAA_YERP3 ;  Q1C5J6, GUAA_YERPA ;
DR   B2K9P0, GUAA_YERPB ;  Q8ZCU4, GUAA_YERPE ;  A9R7Z2, GUAA_YERPG ;
DR   Q1CK82, GUAA_YERPN ;  A4TMS8, GUAA_YERPP ;  Q668A8, GUAA_YERPS ;
DR   B1JSB0, GUAA_YERPY ;  Q5NN19, GUAA_ZYMMO ;
//
ID   6.3.5.3
DE   Phosphoribosylformylglycinamidine synthase.
AN   FGAM synthase.
AN   FGAM synthetase.
AN   FGAR amidotransferase.
AN   FGARAT.
AN   Formylglycinamide ribotide amidotransferase.
AN   Phosphoribosylformylglycinamidine synthetase.
CA   ATP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine +
CA   H(2)O = ADP + phosphate + 2-(formamido)-N(1)-(5-phospho-D-
CA   ribosyl)acetamidine + L-glutamate.
PR   PROSITE; PDOC00405;
DR   Q9M8D3, PUR4_ARATH ;  Q19311, PUR4_CAEEL ;  Q47XX7, PUR4_COLP3 ;
DR   Q54JC8, PUR4_DICDI ;  P35421, PUR4_DROME ;  Q8XA46, PUR4_ECO57 ;
DR   Q0TET1, PUR4_ECOL5 ;  Q8FF26, PUR4_ECOL6 ;  P15254, PUR4_ECOLI ;
DR   Q1R8H7, PUR4_ECOUT ;  Q6D238, PUR4_ERWCT ;  Q4QME6, PUR4_HAEI8 ;
DR   P43847, PUR4_HAEIN ;  Q0I5H4, PUR4_HAES1 ;  Q2SK05, PUR4_HAHCH ;
DR   O15067, PUR4_HUMAN ;  Q5QWY0, PUR4_IDILO ;  Q65RJ7, PUR4_MANSM ;
DR   Q1H2I8, PUR4_METFK ;  Q5SUR0, PUR4_MOUSE ;  Q1D9V4, PUR4_MYXXD ;
DR   Q5F7J4, PUR4_NEIG1 ;  Q9JWC5, PUR4_NEIMA ;  Q9JXK5, PUR4_NEIMB ;
DR   Q9CLW4, PUR4_PASMU ;  Q7N1Z4, PUR4_PHOLL ;  Q6LU24, PUR4_PHOPR ;
DR   Q48LX3, PUR4_PSE14 ;  Q15R69, PUR4_PSEA6 ;  Q9HXN2, PUR4_PSEAE ;
DR   Q4KHS6, PUR4_PSEF5 ;  Q3IHZ2, PUR4_PSEHT ;  Q3KHL4, PUR4_PSEPF ;
DR   Q88P16, PUR4_PSEPK ;  Q886W6, PUR4_PSESM ;  Q4ZX02, PUR4_PSEU2 ;
DR   Q8XYN6, PUR4_RALSO ;  Q57LE6, PUR4_SALCH ;  Q5PIG8, PUR4_SALPA ;
DR   Q8Z4L6, PUR4_SALTI ;  P74881, PUR4_SALTY ;  O14228, PUR4_SCHPO ;
DR   Q12PR7, PUR4_SHEDO ;  Q085S1, PUR4_SHEFN ;  Q8EC57, PUR4_SHEON ;
DR   Q0HKU9, PUR4_SHESM ;  Q0HX47, PUR4_SHESR ;  Q31XT0, PUR4_SHIBS ;
DR   Q32D15, PUR4_SHIDS ;  Q3YYZ8, PUR4_SHISS ;  Q2NS22, PUR4_SODGM ;
DR   Q9KTN2, PUR4_VIBCH ;  Q5E749, PUR4_VIBF1 ;  Q87RW0, PUR4_VIBPA ;
DR   Q8DF81, PUR4_VIBVU ;  Q7MN70, PUR4_VIBVY ;  Q8PGR7, PUR4_XANAC ;
DR   Q8PCQ7, PUR4_XANCP ;  Q9PDF6, PUR4_XYLFA ;  Q87DN2, PUR4_XYLFT ;
DR   P38972, PUR4_YEAST ;  Q1C5E7, PUR4_YERPA ;  Q8ZCQ2, PUR4_YERPE ;
DR   Q1CKD2, PUR4_YERPN ;  Q667W1, PUR4_YERPS ;  B0C6R3, PURL_ACAM1 ;
DR   A5G1X4, PURL_ACICJ ;  B9JFQ3, PURL_AGRRK ;  Q8UEB0, PURL_AGRT5 ;
DR   B9JVW2, PURL_AGRVS ;  A6TLS3, PURL_ALKMQ ;  B8JBS8, PURL_ANAD2 ;
DR   Q2IHC1, PURL_ANADE ;  A7HIJ4, PURL_ANADF ;  B4UIX7, PURL_ANASK ;
DR   Q3M6Z4, PURL_ANAVT ;  B7GFT8, PURL_ANOFW ;  O67691, PURL_AQUAE ;
DR   O28339, PURL_ARCFU ;  A8I8B0, PURL_AZOC5 ;  A7Z249, PURL_BACA2 ;
DR   C3PBN0, PURL_BACAA ;  C3L532, PURL_BACAC ;  A0R8Z6, PURL_BACAH ;
DR   Q81ZH2, PURL_BACAN ;  B7JM85, PURL_BACC0 ;  Q73EN5, PURL_BACC1 ;
DR   B7IUV3, PURL_BACC2 ;  C1EV63, PURL_BACC3 ;  B7H4T6, PURL_BACC4 ;
DR   B7HS32, PURL_BACC7 ;  A7GKH8, PURL_BACCN ;  B9J1K5, PURL_BACCQ ;
DR   Q81IQ3, PURL_BACCR ;  Q63GT3, PURL_BACCZ ;  Q9KF57, PURL_BACHD ;
DR   Q6HPA4, PURL_BACHK ;  Q65MS8, PURL_BACLD ;  A8FAM7, PURL_BACP2 ;
DR   Q5WJ86, PURL_BACSK ;  P12042, PURL_BACSU ;  A9VRF1, PURL_BACWK ;
DR   A1UT47, PURL_BARBK ;  Q6G335, PURL_BARHE ;  Q6FZI9, PURL_BARQU ;
DR   A9IVH5, PURL_BART1 ;  B2IC83, PURL_BEII9 ;  Q89IC0, PURL_BRAJA ;
DR   A5EMI1, PURL_BRASB ;  A4YRR9, PURL_BRASO ;  B2S573, PURL_BRUA1 ;
DR   Q2YNG6, PURL_BRUA2 ;  Q57DR8, PURL_BRUAB ;  A9MAL4, PURL_BRUC2 ;
DR   C0RIH1, PURL_BRUMB ;  Q8YGN1, PURL_BRUME ;  A5VQ15, PURL_BRUO2 ;
DR   B0CLG4, PURL_BRUSI ;  Q8G183, PURL_BRUSU ;  A8MCK2, PURL_CALMQ ;
DR   A8Z6J5, PURL_CAMC1 ;  A7GYY9, PURL_CAMC5 ;  A7I157, PURL_CAMHC ;
DR   A8FM09, PURL_CAMJ8 ;  A7H373, PURL_CAMJD ;  Q9PNY0, PURL_CAMJE ;
DR   A1VZU6, PURL_CAMJJ ;  Q5HUK4, PURL_CAMJR ;  B9KFP6, PURL_CAMLR ;
DR   Q3AD64, PURL_CARHZ ;  Q9A5F0, PURL_CAUCR ;  Q3ARU4, PURL_CHLCH ;
DR   Q8KD17, PURL_CHLTE ;  C3PIW7, PURL_CORA7 ;  Q9RHW9, PURL_CORAM ;
DR   Q8FMM3, PURL_COREF ;  A4QGY6, PURL_CORGB ;  Q8NMI5, PURL_CORGL ;
DR   Q4JXF0, PURL_CORJK ;  B8HRP1, PURL_CYAP4 ;  Q9RXT4, PURL_DEIRA ;
DR   Q833Y9, PURL_ENTFA ;  Q2NAT8, PURL_ERYLH ;  C4L299, PURL_EXISA ;
DR   Q2J4M9, PURL_FRASC ;  A8LCI3, PURL_FRASN ;  Q5L3D2, PURL_GEOKA ;
DR   C5D4I0, PURL_GEOSW ;  A4IJX3, PURL_GEOTN ;  Q7NIR9, PURL_GLOVI ;
DR   Q5FNL0, PURL_GLUOX ;  Q0BRI4, PURL_GRABC ;  B9LT08, PURL_HALLT ;
DR   Q5V2D3, PURL_HALMA ;  B0R4B5, PURL_HALS3 ;  Q9HR49, PURL_HALSA ;
DR   Q18JI5, PURL_HALWD ;  Q7VF52, PURL_HELHP ;  A8ABX6, PURL_IGNH4 ;
DR   Q28QC2, PURL_JANSC ;  Q5FIV1, PURL_LACAC ;  Q037U9, PURL_LACC3 ;
DR   P35852, PURL_LACCA ;  Q1G9F8, PURL_LACDA ;  Q049L7, PURL_LACDB ;
DR   B2GF74, PURL_LACF3 ;  A8YW85, PURL_LACH4 ;  Q9CFE8, PURL_LACLA ;
DR   Q9ZB06, PURL_LACLC ;  A2RJW3, PURL_LACLM ;  Q02Y55, PURL_LACLS ;
DR   Q88U25, PURL_LACPL ;  A5VHT8, PURL_LACRD ;  B2G5B8, PURL_LACRJ ;
DR   Q1WU59, PURL_LACS1 ;  Q38XW7, PURL_LACSS ;  Q6ACC3, PURL_LEIXX ;
DR   B0SB88, PURL_LEPBA ;  Q04QS4, PURL_LEPBJ ;  Q053V5, PURL_LEPBL ;
DR   B0ST16, PURL_LEPBP ;  Q72PR5, PURL_LEPIC ;  Q8F6I3, PURL_LEPIN ;
DR   Q03Y89, PURL_LEUMM ;  Q92AN9, PURL_LISIN ;  C1KW68, PURL_LISMC ;
DR   Q71YP9, PURL_LISMF ;  B8DDY8, PURL_LISMH ;  Q8Y6C1, PURL_LISMO ;
DR   A0AJM3, PURL_LISW6 ;  B9EAY8, PURL_MACCJ ;  Q11IV2, PURL_MESSB ;
DR   A6UX13, PURL_META3 ;  Q8TIT6, PURL_METAC ;  Q46F25, PURL_METBF ;
DR   Q58660, PURL_METJA ;  Q8TY09, PURL_METKA ;  Q8PYK1, PURL_METMA ;
DR   A5UMW9, PURL_METS3 ;  A4YI68, PURL_METS5 ;  B8EPE8, PURL_METSB ;
DR   Q2NEB6, PURL_METST ;  O27427, PURL_METTH ;  P26500, PURL_METTM ;
DR   A0B5C7, PURL_METTP ;  Q2RGU5, PURL_MOOTA ;  A0QAT1, PURL_MYCA1 ;
DR   B1MHY1, PURL_MYCA9 ;  P0A5T9, PURL_MYCBO ;  A1KGT6, PURL_MYCBP ;
DR   C1ALD8, PURL_MYCBT ;  A4T7J3, PURL_MYCGI ;  B8ZSV5, PURL_MYCLB ;
DR   Q50023, PURL_MYCLE ;  Q743F0, PURL_MYCPA ;  A5U0J2, PURL_MYCTA ;
DR   P0A5T8, PURL_MYCTU ;  A1TFE0, PURL_MYCVP ;  Q3IQL3, PURL_NATPD ;
DR   Q1QMU2, PURL_NITHX ;  A6Q3E8, PURL_NITSB ;  Q3ST22, PURL_NITWN ;
DR   Q5Z2C3, PURL_NOCFA ;  A1SPT8, PURL_NOCSJ ;  B2IU46, PURL_NOSP7 ;
DR   Q8YR06, PURL_NOSS1 ;  Q2G630, PURL_NOVAD ;  Q8ES96, PURL_OCEIH ;
DR   A6X1J9, PURL_OCHA4 ;  A1B943, PURL_PARDP ;  A7HWB1, PURL_PARL1 ;
DR   Q3B3Y0, PURL_PELLD ;  Q4FLJ4, PURL_PELUB ;  A9BIH4, PURL_PETMO ;
DR   Q6KZR2, PURL_PICTO ;  Q6A6C0, PURL_PROAC ;  A3PA50, PURL_PROM0 ;
DR   A2BZA6, PURL_PROM1 ;  A8G1Z0, PURL_PROM2 ;  A2C5J9, PURL_PROM3 ;
DR   A2BTV9, PURL_PROM5 ;  Q31DI1, PURL_PROM9 ;  Q7VEK9, PURL_PROMA ;
DR   Q7V9E5, PURL_PROMM ;  Q7V3R5, PURL_PROMP ;  A2BNC9, PURL_PROMS ;
DR   Q46I59, PURL_PROMT ;  Q9UXW6, PURL_PYRAB ;  Q8ZZJ7, PURL_PYRAE ;
DR   A4WMV7, PURL_PYRAR ;  A3MXD4, PURL_PYRCJ ;  Q8U491, PURL_PYRFU ;
DR   O59621, PURL_PYRHO ;  A1RQQ2, PURL_PYRIL ;  Q5JFL7, PURL_PYRKO ;
DR   A9WV65, PURL_RENSM ;  B3PPS1, PURL_RHIE6 ;  Q2K7X0, PURL_RHIEC ;
DR   Q9KH12, PURL_RHIFR ;  Q1MG23, PURL_RHIL3 ;  Q98NN7, PURL_RHILO ;
DR   B5ZQU1, PURL_RHILW ;  Q92PH7, PURL_RHIME ;  C3MD72, PURL_RHISN ;
DR   C0ZP44, PURL_RHOE4 ;  C1ATA2, PURL_RHOOB ;  Q2ITQ2, PURL_RHOP2 ;
DR   Q07R72, PURL_RHOP5 ;  Q6N9F2, PURL_RHOPA ;  Q218N3, PURL_RHOPB ;
DR   Q13AA1, PURL_RHOPS ;  B3Q7H9, PURL_RHOPT ;  Q2RWI3, PURL_RHORT ;
DR   Q3J273, PURL_RHOS4 ;  A4WQY3, PURL_RHOS5 ;  B9KSY5, PURL_RHOSK ;
DR   Q0S766, PURL_RHOSR ;  Q163V9, PURL_ROSDO ;  Q2RZ77, PURL_SALRD ;
DR   Q5LS98, PURL_SILPO ;  Q1GHL5, PURL_SILST ;  A6U9L9, PURL_SINMW ;
DR   A7X0W1, PURL_STAA1 ;  A6U0N7, PURL_STAA2 ;  Q2FI09, PURL_STAA3 ;
DR   Q2FZJ0, PURL_STAA8 ;  A5IRV6, PURL_STAA9 ;  Q2YX54, PURL_STAAB ;
DR   Q5HH15, PURL_STAAC ;  A6QFS7, PURL_STAAE ;  P65900, PURL_STAAM ;
DR   P65901, PURL_STAAN ;  Q6GI15, PURL_STAAR ;  Q6GAE4, PURL_STAAS ;
DR   A8Z1L1, PURL_STAAT ;  Q8NX92, PURL_STAAW ;  B9DQ38, PURL_STACT ;
DR   Q5HQA1, PURL_STAEQ ;  Q8CPN9, PURL_STAES ;  Q4L578, PURL_STAHJ ;
DR   Q49WJ3, PURL_STAS1 ;  Q82FW4, PURL_STRAW ;  Q9RKK5, PURL_STRCO ;
DR   Q4J8F8, PURL_SULAC ;  Q30T55, PURL_SULDN ;  C3N674, PURL_SULIA ;
DR   C4KHN7, PURL_SULIK ;  C3MQF3, PURL_SULIL ;  C3MW31, PURL_SULIM ;
DR   C3NH14, PURL_SULIN ;  C3NEN0, PURL_SULIY ;  A6QAK6, PURL_SULNB ;
DR   Q9UX24, PURL_SULSO ;  Q970V6, PURL_SULTO ;  Q67KF8, PURL_SYMTH ;
DR   Q55041, PURL_SYNE7 ;  Q2JQL7, PURL_SYNJA ;  Q2JI39, PURL_SYNJB ;
DR   Q5N1Y6, PURL_SYNP6 ;  A5GHL4, PURL_SYNPW ;  Q7UA92, PURL_SYNPX ;
DR   Q3B100, PURL_SYNS9 ;  Q3ANP7, PURL_SYNSC ;  P72644, PURL_SYNY3 ;
DR   Q9HJA4, PURL_THEAC ;  Q8DIA7, PURL_THEEB ;  Q47TL8, PURL_THEFY ;
DR   C5A4U6, PURL_THEGJ ;  A8F8I3, PURL_THELT ;  Q9X0X3, PURL_THEMA ;
DR   B1YBM5, PURL_THENV ;  B0KBQ5, PURL_THEP3 ;  B0K3Q4, PURL_THEPX ;
DR   B9KZ38, PURL_THERP ;  C6A0I0, PURL_THESM ;  Q72IH7, PURL_THET2 ;
DR   Q5SMH8, PURL_THET8 ;  Q8RBK5, PURL_THETN ;  Q97BD5, PURL_THEVO ;
DR   Q83H66, PURL_TROW8 ;  Q83FE8, PURL_TROWT ;  Q7M9L5, PURL_WOLSU ;
DR   Q9REQ6, PURL_ZYMMO ;  B0C7S1, PURQ_ACAM1 ;  Q1IPG4, PURQ_ACIBL ;
DR   A6TLS2, PURQ_ALKMQ ;  Q2IG97, PURQ_ANADE ;  Q3MG53, PURQ_ANAVT ;
DR   B7GFT7, PURQ_ANOFW ;  O67190, PURQ_AQUAE ;  O29008, PURQ_ARCFU ;
DR   A7Z248, PURQ_BACA2 ;  C3PBM9, PURQ_BACAA ;  C3L531, PURQ_BACAC ;
DR   A0R8Z5, PURQ_BACAH ;  Q81ZH3, PURQ_BACAN ;  B7JM84, PURQ_BACC0 ;
DR   Q73EN6, PURQ_BACC1 ;  B7IUV2, PURQ_BACC2 ;  C1EV62, PURQ_BACC3 ;
DR   B7H4T5, PURQ_BACC4 ;  B7HS31, PURQ_BACC7 ;  A7GKH7, PURQ_BACCN ;
DR   B9J1K4, PURQ_BACCQ ;  Q81IQ4, PURQ_BACCR ;  Q63GT4, PURQ_BACCZ ;
DR   Q9KF58, PURQ_BACHD ;  Q6HPA5, PURQ_BACHK ;  Q65MS9, PURQ_BACLD ;
DR   A8FAM6, PURQ_BACP2 ;  Q5WJ87, PURQ_BACSK ;  P12041, PURQ_BACSU ;
DR   A9VRF0, PURQ_BACWK ;  Q6G336, PURQ_BARHE ;  Q6FZJ0, PURQ_BARQU ;
DR   Q89IB6, PURQ_BRAJA ;  C0ZKC5, PURQ_BREBN ;  Q2YNG3, PURQ_BRUA2 ;
DR   Q57DR5, PURQ_BRUAB ;  Q8YGN4, PURQ_BRUME ;  Q8G180, PURQ_BRUSU ;
DR   Q9PHZ7, PURQ_CAMJE ;  Q3AD65, PURQ_CARHZ ;  Q9A5F3, PURQ_CAUCR ;
DR   Q3AS25, PURQ_CHLCH ;  B3QMT1, PURQ_CHLP8 ;  Q8KCS5, PURQ_CHLTE ;
DR   Q9RHX0, PURQ_CORAM ;  Q8FMM2, PURQ_COREF ;  Q8NMI4, PURQ_CORGL ;
DR   Q4JXF1, PURQ_CORJK ;  Q3Z9H5, PURQ_DEHE1 ;  Q1J2B6, PURQ_DEIGD ;
DR   Q9RXT3, PURQ_DEIRA ;  Q833Y8, PURQ_ENTFA ;  B1YJ04, PURQ_EXIS2 ;
DR   C4L298, PURQ_EXISA ;  Q2J4N0, PURQ_FRASC ;  Q5L3D3, PURQ_GEOKA ;
DR   C5D4H9, PURQ_GEOSW ;  A4IJX2, PURQ_GEOTN ;  Q7NL01, PURQ_GLOVI ;
DR   Q5FNL1, PURQ_GLUOX ;  Q9HNU2, PURQ_HALSA ;  Q18FM4, PURQ_HALWD ;
DR   Q7VFQ4, PURQ_HELHP ;  Q28PA2, PURQ_JANSC ;  Q5FIV0, PURQ_LACAC ;
DR   Q037U8, PURQ_LACC3 ;  P35851, PURQ_LACCA ;  B3WF98, PURQ_LACCB ;
DR   Q1G9F7, PURQ_LACDA ;  B2GF73, PURQ_LACF3 ;  Q9CFE7, PURQ_LACLA ;
DR   Q9ZB07, PURQ_LACLC ;  Q88U24, PURQ_LACPL ;  A5VHT7, PURQ_LACRD ;
DR   B2G5B7, PURQ_LACRJ ;  Q1WU60, PURQ_LACS1 ;  Q38XW8, PURQ_LACSS ;
DR   Q6ACD4, PURQ_LEIXX ;  Q72UH6, PURQ_LEPIC ;  Q8F0I2, PURQ_LEPIN ;
DR   Q92AN8, PURQ_LISIN ;  C1KW69, PURQ_LISMC ;  Q71YP8, PURQ_LISMF ;
DR   B8DDY7, PURQ_LISMH ;  Q8Y6C0, PURQ_LISMO ;  A0AJM4, PURQ_LISW6 ;
DR   B1HTV3, PURQ_LYSSC ;  Q11IV0, PURQ_MESSB ;  Q8TPF0, PURQ_METAC ;
DR   Q468N4, PURQ_METBF ;  Q59042, PURQ_METJA ;  Q8TX85, PURQ_METKA ;
DR   A4G010, PURQ_METM5 ;  A6VIG8, PURQ_METM7 ;  Q8PTB0, PURQ_METMA ;
DR   Q6M0U0, PURQ_METMP ;  Q2NF29, PURQ_METST ;  O26270, PURQ_METTH ;
DR   A0B5C6, PURQ_METTP ;  Q2RGU4, PURQ_MOOTA ;  P65903, PURQ_MYCBO ;
DR   O05756, PURQ_MYCLE ;  Q743F9, PURQ_MYCPA ;  P65902, PURQ_MYCTU ;
DR   Q3IMR2, PURQ_NATPD ;  Q1QMU3, PURQ_NITHX ;  Q3ST24, PURQ_NITWN ;
DR   Q5Z2C8, PURQ_NOCFA ;  Q8YU79, PURQ_NOSS1 ;  Q2G9J6, PURQ_NOVAD ;
DR   Q8ES97, PURQ_OCEIH ;  Q3B397, PURQ_PELLD ;  Q4FLJ5, PURQ_PELUB ;
DR   Q6L0V9, PURQ_PICTO ;  Q6A6B0, PURQ_PROAC ;  Q31B97, PURQ_PROM9 ;
DR   Q7VC88, PURQ_PROMA ;  Q7V834, PURQ_PROMM ;  Q7V1S5, PURQ_PROMP ;
DR   Q46LE9, PURQ_PROMT ;  Q9UXW5, PURQ_PYRAB ;  Q8ZZJ9, PURQ_PYRAE ;
DR   Q8U492, PURQ_PYRFU ;  O59619, PURQ_PYRHO ;  Q5JFP4, PURQ_PYRKO ;
DR   Q2K7X5, PURQ_RHIEC ;  Q1MG27, PURQ_RHIL3 ;  Q98NN0, PURQ_RHILO ;
DR   Q92PI1, PURQ_RHIME ;  Q2ITP9, PURQ_RHOP2 ;  Q6N376, PURQ_RHOPA ;
DR   Q218N7, PURQ_RHOPB ;  Q2RWI2, PURQ_RHORT ;  Q3J4K2, PURQ_RHOS4 ;
DR   Q0S774, PURQ_RHOSR ;  Q167J3, PURQ_ROSDO ;  Q1AXB7, PURQ_RUBXD ;
DR   Q2S567, PURQ_SALRD ;  Q5LS78, PURQ_SILPO ;  Q1GGM0, PURQ_SILST ;
DR   Q1GVL0, PURQ_SPHAL ;  Q2FI10, PURQ_STAA3 ;  Q2FZJ1, PURQ_STAA8 ;
DR   Q2YX55, PURQ_STAAB ;  Q5HH16, PURQ_STAAC ;  P65904, PURQ_STAAM ;
DR   P99166, PURQ_STAAN ;  Q6GI16, PURQ_STAAR ;  Q6GAE5, PURQ_STAAS ;
DR   Q8NX93, PURQ_STAAW ;  Q5HQA2, PURQ_STAEQ ;  Q8CPP0, PURQ_STAES ;
DR   Q4L577, PURQ_STAHJ ;  Q49WJ2, PURQ_STAS1 ;  Q82FW3, PURQ_STRAW ;
DR   Q9RKK6, PURQ_STRCO ;  Q30TB2, PURQ_SULDN ;  Q9UX21, PURQ_SULSO ;
DR   Q67KF7, PURQ_SYMTH ;  Q31Q18, PURQ_SYNE7 ;  Q2JWK2, PURQ_SYNJA ;
DR   Q2JPK0, PURQ_SYNJB ;  Q5N459, PURQ_SYNP6 ;  Q7U831, PURQ_SYNPX ;
DR   Q3AYR1, PURQ_SYNS9 ;  Q3AII4, PURQ_SYNSC ;  Q55843, PURQ_SYNY3 ;
DR   Q9HIM1, PURQ_THEAC ;  Q8DGX5, PURQ_THEEB ;  A8F8I4, PURQ_THELT ;
DR   Q9X0X2, PURQ_THEMA ;  B9KZ37, PURQ_THERP ;  Q72IH9, PURQ_THET2 ;
DR   Q5SI57, PURQ_THET8 ;  Q8RBK6, PURQ_THETN ;  Q97C36, PURQ_THEVO ;
DR   Q73MV2, PURQ_TREDE ;  Q7M9X7, PURQ_WOLSU ;  Q5NMA4, PURQ_ZYMMO ;
//
ID   6.3.5.4
DE   Asparagine synthase (glutamine-hydrolyzing).
AN   AS-B.
AN   Asparagine synthetase (glutamine-hydrolyzing).
AN   Asparagine synthetase B.
AN   Glutamine-dependent asparagine synthetase.
CA   ATP + L-aspartate + L-glutamine + H(2)O = AMP + diphosphate +
CA   L-asparagine + L-glutamate.
CC   -!- The enzyme from Escherichia coli has two active sites that are
CC       connected by an intramolecular ammonia tunnel.
CC   -!- The enzyme catalyzes three distinct chemical reactions: glutamine
CC       hydrolysis to yield ammonia takes place in the N-terminal domain.
CC   -!- The C-terminal active site mediates both the synthesis of a beta-
CC       aspartyl-AMP intermediate and its subsequent reaction with ammonia.
CC   -!- The ammonia released is channeled to the other active site to yield
CC       asparagine.
PR   PROSITE; PDOC00406;
DR   P54420, ASNB_BACSU ;  P22106, ASNB_ECOLI ;  Q58516, ASNH1_METJA;
DR   Q58456, ASNH2_METJA;  P42113, ASNH_BACSU ;  P64248, ASNH_MYCBO ;
DR   P64247, ASNH_MYCTU ;  O05272, ASNO_BACSU ;  P49092, ASNS1_LOTJA;
DR   P19251, ASNS1_PEA  ;  P49089, ASNS1_YEAST;  P49093, ASNS2_LOTJA;
DR   P19252, ASNS2_PEA  ;  P49090, ASNS2_YEAST;  P49078, ASNS_ARATH ;
DR   P31752, ASNS_ASPOF ;  Q1LZA3, ASNS_BOVIN ;  P49091, ASNS_BRAOL ;
DR   Q5ZJU3, ASNS_CHICK ;  P19891, ASNS_CRIGR ;  Q54MB4, ASNS_DICDI ;
DR   P08243, ASNS_HUMAN ;  P49094, ASNS_MAIZE ;  P17714, ASNS_MESAU ;
DR   Q5UQE1, ASNS_MIMIV ;  Q61024, ASNS_MOUSE ;  Q43011, ASNS_ORYSJ ;
DR   Q5R6W9, ASNS_PONAB ;  P49088, ASNS_RAT   ;  O24338, ASNS_SANAU ;
DR   P78753, ASNS_SCHPO ;  O24661, ASNS_TRIVS ;
//
ID   6.3.5.5
DE   Carbamoyl-phosphate synthase (glutamine-hydrolyzing).
AN   Carbamoyl phosphate synthetase.
AN   Carbamoyl-phosphate synthetase (glutamine-hydrolyzing).
AN   Carbamoylphosphate synthetase II.
AN   Carbamyl phosphate synthetase (glutamine).
AN   CPS.
AN   GD-CPSase.
AN   Glutamine-dependent carbamoyl-phosphate synthase.
AN   Glutamine-dependent carbamyl phosphate synthetase.
CA   2 ATP + L-glutamine + HCO(3)(-) + H(2)O = 2 ADP + phosphate + L-glutamate
CA   + carbamoyl phosphate.
CC   -!- The product carbamoyl phosphate is an intermediate in the
CC       biosynthesis of arginine and the pyrimidine nucleotides.
CC   -!- The enzyme from Escherichia coli has three separate active sites,
CC       which are connected by a molecular tunnel that is almost 100 A in
CC       length.
CC   -!- The amidotransferase domain within the small subunit of the enzyme
CC       hydrolyzes glutamine to ammonia via a thioester intermediate.
CC   -!- The ammonia migrates through the interior of the protein, where it
CC       reacts with carboxy phosphate to produce the carbamate intermediate.
CC   -!- The carboxy-phosphate intermediate is formed by the phosphorylation
CC       of bicarbonate by ATP at a site contained within the N-terminal half
CC       of the large subunit.
CC   -!- The carbamate intermediate is transported through the interior of the
CC       protein to a second site within the C-terminal half of the large
CC       subunit, where it is phosphorylated by another ATP to yield the final
CC       product, carbamoyl phosphate.
CC   -!- Formerly EC 2.7.2.9.
PR   PROSITE; PDOC00405;
PR   PROSITE; PDOC00676;
PR   PROSITE; PDOC50975;
DR   Q6F8M7, CARA_ACIAD ;  Q8UDF7, CARA_AGRT5 ;  B2URJ0, CARA_AKKM8 ;
DR   O66727, CARA_AQUAE ;  O28995, CARA_ARCFU ;  Q752N9, CARA_ASHGO ;
DR   A1CA18, CARA_ASPCL ;  Q4WU09, CARA_ASPFU ;  A2R9B9, CARA_ASPNC ;
DR   Q2U913, CARA_ASPOR ;  Q81WF1, CARA_BACAN ;  Q732I2, CARA_BACC1 ;
DR   P52557, CARA_BACCL ;  Q819S2, CARA_BACCR ;  Q636D9, CARA_BACCZ ;
DR   Q9K9V8, CARA_BACHD ;  Q6HES7, CARA_BACHK ;  P25993, CARA_BACSU ;
DR   A1UTE8, CARA_BARBK ;  Q6G5M0, CARA_BARHE ;  Q6FZ66, CARA_BARQU ;
DR   A9IWF8, CARA_BART1 ;  B3DQ31, CARA_BIFLD ;  Q8G816, CARA_BIFLO ;
DR   B7GPW1, CARA_BIFLS ;  Q89DR8, CARA_BRAJA ;  B2S6U9, CARA_BRUA1 ;
DR   Q2YM22, CARA_BRUA2 ;  Q57C28, CARA_BRUAB ;  A9M6F1, CARA_BRUC2 ;
DR   C0REC2, CARA_BRUMB ;  Q8YIB8, CARA_BRUME ;  A5VRM1, CARA_BRUO2 ;
DR   B0CHS0, CARA_BRUSI ;  Q8FZJ8, CARA_BRUSU ;  P57245, CARA_BUCAI ;
DR   Q8K9Z6, CARA_BUCAP ;  P59576, CARA_BUCBP ;  Q9PMG8, CARA_CAMJE ;
DR   Q5AML6, CARA_CANAL ;  Q6FQ30, CARA_CANGA ;  Q9A4J7, CARA_CAUCR ;
DR   Q2H132, CARA_CHAGB ;  Q8KGA2, CARA_CHLTE ;  Q97FT2, CARA_CLOAB ;
DR   Q8XHB2, CARA_CLOPE ;  Q1DUF5, CARA_COCIM ;  Q6NH15, CARA_CORDI ;
DR   Q8FT41, CARA_COREF ;  P58893, CARA_CORGL ;  O19886, CARA_CYACA ;
DR   Q6BJG4, CARA_DEBHA ;  Q1IWN0, CARA_DEIGD ;  Q9RWI4, CARA_DEIRA ;
DR   C6C0A9, CARA_DESAD ;  B8IZS6, CARA_DESDA ;  C4XRH8, CARA_DESMR ;
DR   Q726J4, CARA_DESVH ;  Q8KZA0, CARA_DESVM ;  A1VA26, CARA_DESVV ;
DR   P0A6F2, CARA_ECO57 ;  Q8FLB1, CARA_ECOL6 ;  P0A6F1, CARA_ECOLI ;
DR   Q5BB37, CARA_EMENI ;  Q6D0C8, CARA_ERWCT ;  Q8RG87, CARA_FUSNN ;
DR   Q6B940, CARA_GRATL ;  Q7VP66, CARA_HAEDU ;  Q8RSS4, CARA_HALER ;
DR   B0R6F1, CARA_HALS3 ;  Q9HP42, CARA_HALSA ;  Q17VI1, CARA_HELAH ;
DR   Q7VHS5, CARA_HELHP ;  Q9ZJY9, CARA_HELPJ ;  O25835, CARA_HELPY ;
DR   Q0BY73, CARA_HYPNA ;  P87183, CARA_HYPVI ;  Q6CIQ1, CARA_KLULA ;
DR   Q9CF80, CARA_LACLA ;  Q9L4N5, CARA_LACLM ;  P77885, CARA_LACPL ;
DR   Q1MPN3, CARA_LAWIP ;  Q04R57, CARA_LEPBJ ;  Q04ZG6, CARA_LEPBL ;
DR   Q72PK5, CARA_LEPIC ;  Q8F6R2, CARA_LEPIN ;  Q92AH2, CARA_LISIN ;
DR   Q71YI0, CARA_LISMF ;  Q8Y664, CARA_LISMO ;  Q0AMR3, CARA_MARMM ;
DR   Q8TNY3, CARA_METAC ;  Q58425, CARA_METJA ;  Q8TY15, CARA_METKA ;
DR   A4G0Y3, CARA_METM5 ;  A9A972, CARA_METM6 ;  A6VHH7, CARA_METM7 ;
DR   Q8Q0U4, CARA_METMA ;  Q6LWW5, CARA_METMP ;  A4YI77, CARA_METS5 ;
DR   O27079, CARA_METTH ;  A6UQN4, CARA_METVS ;  Q7U055, CARA_MYCBO ;
DR   Q9CCR3, CARA_MYCLE ;  Q741H2, CARA_MYCPA ;  P71811, CARA_MYCTU ;
DR   Q50983, CARA_NEIGO ;  Q9JVZ6, CARA_NEIMA ;  Q9JXX4, CARA_NEIMB ;
DR   A1CZ92, CARA_NEOFI ;  P22572, CARA_NEUCR ;  Q8YXQ7, CARA_NOSS1 ;
DR   Q8CXH8, CARA_OCEIH ;  A6WZJ5, CARA_OCHA4 ;  Q9CKV3, CARA_PASMU ;
DR   Q3A450, CARA_PELCD ;  Q0U5H7, CARA_PHANO ;  Q7N8W2, CARA_PHOLL ;
DR   Q6LUK6, CARA_PHOPR ;  B1XUM3, CARA_POLNS ;  A4SXM1, CARA_POLSQ ;
DR   P51201, CARA_PORPU ;  Q1XDT6, CARA_PORYE ;  B4S5S1, CARA_PROA2 ;
DR   P38098, CARA_PSEAE ;  Q88DU5, CARA_PSEPK ;  Q87WP3, CARA_PSESM ;
DR   P38099, CARA_PSEST ;  Q8ZY49, CARA_PYRAE ;  Q8U086, CARA_PYRFU ;
DR   Q8XZ85, CARA_RALSO ;  Q98IA7, CARA_RHILO ;  Q92N95, CARA_RHIME ;
DR   Q7UGJ6, CARA_RHOBA ;  Q9JP87, CARA_RUBGE ;  Q8Z9L8, CARA_SALTI ;
DR   P14845, CARA_SALTY ;  O60060, CARA_SCHPO ;  Q8EHS6, CARA_SHEON ;
DR   Q5LTN6, CARA_SILPO ;  Q5HGN0, CARA_STAAC ;  P63729, CARA_STAAM ;
DR   P99147, CARA_STAAN ;  Q6GHN3, CARA_STAAR ;  Q6GA11, CARA_STAAS ;
DR   P63730, CARA_STAAW ;  Q5HPY9, CARA_STAEQ ;  Q8CPJ5, CARA_STAES ;
DR   Q4L5Q4, CARA_STAHJ ;  Q49WY3, CARA_STAS1 ;  P63731, CARA_STRA3 ;
DR   P63732, CARA_STRA5 ;  Q827Q8, CARA_STRAW ;  Q9KXR5, CARA_STRCO ;
DR   Q8DUP4, CARA_STRMU ;  P63735, CARA_STRP1 ;  P0DA12, CARA_STRP3 ;
DR   Q5XCR8, CARA_STRP6 ;  P58894, CARA_STRP8 ;  P63733, CARA_STRPN ;
DR   P0DA13, CARA_STRPQ ;  P63734, CARA_STRR6 ;  Q4J8E9, CARA_SULAC ;
DR   Q59968, CARA_SULSO ;  Q970U8, CARA_SULTO ;  Q67Q55, CARA_SYMTH ;
DR   Q31LB7, CARA_SYNE7 ;  Q5N0L0, CARA_SYNP6 ;  Q7U7F9, CARA_SYNPX ;
DR   A5GTM5, CARA_SYNR3 ;  P74587, CARA_SYNY3 ;  C5BQ30, CARA_TERTT ;
DR   Q9HK16, CARA_THEAC ;  Q8DKU5, CARA_THEEB ;  Q9WZ28, CARA_THEMA ;
DR   Q72GZ0, CARA_THET2 ;  Q5SLL3, CARA_THET8 ;  Q8RBK1, CARA_THETN ;
DR   Q97AJ4, CARA_THEVO ;  B8GNX4, CARA_THISH ;  Q9KPH8, CARA_VIBCH ;
DR   Q87SF4, CARA_VIBPA ;  Q8DEM1, CARA_VIBVU ;  Q7MNU1, CARA_VIBVY ;
DR   Q8D3H7, CARA_WIGBR ;  P58895, CARA_XANAC ;  P58896, CARA_XANCP ;
DR   Q9PEC2, CARA_XYLFA ;  Q87EB9, CARA_XYLFT ;  Q6C9Y4, CARA_YARLI ;
DR   P07258, CARA_YEAST ;  Q8ZIL5, CARA_YERPE ;  Q66ER8, CARA_YERPS ;
DR   O50235, CARA_ZYMMO ;  O67869, CARB1_AQUAE;  Q58773, CARB1_METJA;
DR   Q8TWX0, CARB1_METKA;  O67233, CARB2_AQUAE;  Q58776, CARB2_METJA;
DR   Q8TUT7, CARB2_METKA;  Q1IPK2, CARB_ACIBL ;  C1F1S6, CARB_ACIC5 ;
DR   Q8UDE9, CARB_AGRT5 ;  O28994, CARB_ARCFU ;  A1R6Z3, CARB_ARTAT ;
DR   B8H8U5, CARB_ARTCA ;  A0JX72, CARB_ARTS2 ;  Q75D66, CARB_ASHGO ;
DR   C3P656, CARB_BACAA ;  C3L740, CARB_BACAC ;  A0RHQ8, CARB_BACAH ;
DR   Q81WF2, CARB_BACAN ;  B7JJX3, CARB_BACC0 ;  Q732I3, CARB_BACC1 ;
DR   B7IUP6, CARB_BACC2 ;  C1EPQ0, CARB_BACC3 ;  B7H6M2, CARB_BACC4 ;
DR   B7HLM0, CARB_BACC7 ;  P46537, CARB_BACCL ;  A7GRL1, CARB_BACCN ;
DR   B9IVW3, CARB_BACCQ ;  Q819S3, CARB_BACCR ;  Q636E0, CARB_BACCZ ;
DR   Q9K9V9, CARB_BACHD ;  Q6HES8, CARB_BACHK ;  P25994, CARB_BACSU ;
DR   A9VTC6, CARB_BACWK ;  C5C687, CARB_BEUC1 ;  B8DTW3, CARB_BIFA0 ;
DR   A1A0T4, CARB_BIFAA ;  B3DQ32, CARB_BIFLD ;  Q8G815, CARB_BIFLO ;
DR   B7GPW2, CARB_BIFLS ;  Q8YIC2, CARB_BRUME ;  Q8FZJ3, CARB_BRUSU ;
DR   P57244, CARB_BUCAI ;  Q8K9Z7, CARB_BUCAP ;  P59448, CARB_BUCBP ;
DR   Q9PIL7, CARB_CAMJE ;  Q9A4D6, CARB_CAUCR ;  A5CRX5, CARB_CLAM3 ;
DR   B0REV9, CARB_CLAMS ;  Q97FT3, CARB_CLOAB ;  A6LPD9, CARB_CLOB8 ;
DR   B2UX86, CARB_CLOBA ;  B2THH3, CARB_CLOBB ;  C1FNY3, CARB_CLOBJ ;
DR   A7GE89, CARB_CLOBL ;  B1KT07, CARB_CLOBM ;  Q0TM79, CARB_CLOP1 ;
DR   Q8XHB3, CARB_CLOPE ;  A9KI94, CARB_CLOPH ;  Q0SPY4, CARB_CLOPS ;
DR   Q8FT42, CARB_COREF ;  P58939, CARB_CORGL ;  C1CXR4, CARB_DEIDV ;
DR   Q1IWM0, CARB_DEIGD ;  Q9RWK0, CARB_DEIRA ;  B1I4M8, CARB_DESAP ;
DR   P63737, CARB_ECO57 ;  Q8FLB0, CARB_ECOL6 ;  P00968, CARB_ECOLI ;
DR   Q834E2, CARB_ENTFA ;  C4ZEK2, CARB_EUBR3 ;  B1YIR9, CARB_EXIS2 ;
DR   C4L5W3, CARB_EXISA ;  Q8RG86, CARB_FUSNN ;  C1A4I5, CARB_GEMAT ;
DR   O50302, CARB_GEOSE ;  Q7VP67, CARB_HAEDU ;  Q8RSS3, CARB_HALER ;
DR   B8D1H3, CARB_HALOH ;  Q9HP43, CARB_HALSA ;  Q9ZKT2, CARB_HELPJ ;
DR   O25577, CARB_HELPY ;  A2BJL3, CARB_HYPBU ;  A6WCC6, CARB_KINRD ;
DR   B2GI87, CARB_KOCRD ;  Q5FJC0, CARB_LACAC ;  Q038Z2, CARB_LACC3 ;
DR   B3WEF5, CARB_LACCB ;  Q047M8, CARB_LACDB ;  B2GD06, CARB_LACF3 ;
DR   A8YVZ3, CARB_LACH4 ;  Q74J34, CARB_LACJO ;  Q9CFV2, CARB_LACLA ;
DR   O32771, CARB_LACLM ;  Q02YG5, CARB_LACLS ;  P77886, CARB_LACPL ;
DR   A5VHN6, CARB_LACRD ;  B2G564, CARB_LACRJ ;  Q1WVA9, CARB_LACS1 ;
DR   Q38X24, CARB_LACSS ;  Q72NF1, CARB_LEPIC ;  Q8F832, CARB_LEPIN ;
DR   B1MZ74, CARB_LEUCK ;  Q03WW7, CARB_LEUMM ;  Q92AH3, CARB_LISIN ;
DR   C1KWD4, CARB_LISMC ;  Q71YI1, CARB_LISMF ;  B8DDR7, CARB_LISMH ;
DR   Q8Y665, CARB_LISMO ;  A0AJU0, CARB_LISW6 ;  B1HQC1, CARB_LYSSC ;
DR   B9EB69, CARB_MACCJ ;  Q8TNY4, CARB_METAC ;  A7I6J1, CARB_METB6 ;
DR   P13258, CARB_METBA ;  Q469Z7, CARB_METBF ;  Q2FLD9, CARB_METHJ ;
DR   A2SQ53, CARB_METLZ ;  P58944, CARB_METMA ;  A3CU73, CARB_METMJ ;
DR   B8GEA3, CARB_METPE ;  A5UKG5, CARB_METS3 ;  O27077, CARB_METTH ;
DR   A0B8K9, CARB_METTP ;  C5CCF1, CARB_MICLC ;  Q7U054, CARB_MYCBO ;
DR   A4TBY6, CARB_MYCGI ;  Q9CCR2, CARB_MYCLE ;  A3PZ65, CARB_MYCSJ ;
DR   A1UFK4, CARB_MYCSK ;  Q1B9F9, CARB_MYCSS ;  P57689, CARB_MYCTU ;
DR   A1T8H1, CARB_MYCVP ;  Q1D6Y8, CARB_MYXXD ;  B2A170, CARB_NATTJ ;
DR   Q59599, CARB_NEIGO ;  Q9JW02, CARB_NEIMA ;  Q9JXW8, CARB_NEIMB ;
DR   Q8YQL2, CARB_NOSS1 ;  Q04H29, CARB_OENOB ;  Q9CKV0, CARB_PASMU ;
DR   Q03HB0, CARB_PEDPA ;  A5D508, CARB_PELTS ;  Q6A914, CARB_PROAC ;
DR   P38100, CARB_PSEAE ;  Q88DU6, CARB_PSEPK ;  Q87WP4, CARB_PSESM ;
DR   Q8ZY48, CARB_PYRAE ;  Q8U085, CARB_PYRFU ;  Q8XZ83, CARB_RALSO ;
DR   A9WSA8, CARB_RENSM ;  Q98I87, CARB_RHILO ;  Q92PZ4, CARB_RHIME ;
DR   Q7UJ58, CARB_RHOBA ;  Q1AVY9, CARB_RUBXD ;  Q8Z9L7, CARB_SALTI ;
DR   P14846, CARB_SALTY ;  O94313, CARB_SCHPO ;  P63738, CARB_SHIFL ;
DR   A7X1F4, CARB_STAA1 ;  A6U122, CARB_STAA2 ;  Q2FHN5, CARB_STAA3 ;
DR   Q2FZ72, CARB_STAA8 ;  A5IS88, CARB_STAA9 ;  Q2YXG5, CARB_STAAB ;
DR   Q5HGM9, CARB_STAAC ;  A6QGA4, CARB_STAAE ;  P63739, CARB_STAAM ;
DR   P63740, CARB_STAAN ;  Q6GHN2, CARB_STAAR ;  Q6GA10, CARB_STAAS ;
DR   A8Z3P0, CARB_STAAT ;  P58940, CARB_STAAW ;  B9DPN2, CARB_STACT ;
DR   Q5HPY8, CARB_STAEQ ;  Q8CPJ4, CARB_STAES ;  Q4L5Q5, CARB_STAHJ ;
DR   Q49WY4, CARB_STAS1 ;  Q3K150, CARB_STRA1 ;  Q8E5F5, CARB_STRA3 ;
DR   Q8DZQ7, CARB_STRA5 ;  Q827Q7, CARB_STRAW ;  Q9KXR6, CARB_STRCO ;
DR   C0M756, CARB_STRE4 ;  A8AX83, CARB_STRGC ;  B1W463, CARB_STRGG ;
DR   Q8DUP3, CARB_STRMU ;  Q9A0C6, CARB_STRP1 ;  Q04K48, CARB_STRP2 ;
DR   P0DA14, CARB_STRP3 ;  B5E512, CARB_STRP4 ;  Q5XCR6, CARB_STRP6 ;
DR   C1C7Q3, CARB_STRP7 ;  P58941, CARB_STRP8 ;  A2RF60, CARB_STRPG ;
DR   B1IC65, CARB_STRPI ;  B8ZJT9, CARB_STRPJ ;  Q97QE4, CARB_STRPN ;
DR   P0DA15, CARB_STRPQ ;  B2IQ67, CARB_STRPS ;  B5XKW2, CARB_STRPZ ;
DR   Q8CWR0, CARB_STRR6 ;  C0MEH1, CARB_STRS7 ;  A3CNI5, CARB_STRSV ;
DR   Q5M0W9, CARB_STRT1 ;  Q5M5F6, CARB_STRT2 ;  Q03LT8, CARB_STRTD ;
DR   B9DRV7, CARB_STRU0 ;  C1CEM9, CARB_STRZJ ;  C1CL09, CARB_STRZP ;
DR   C1CR31, CARB_STRZT ;  Q4J8E8, CARB_SULAC ;  C3N664, CARB_SULIA ;
DR   C4KHM7, CARB_SULIK ;  C3MQE3, CARB_SULIL ;  C3MW21, CARB_SULIM ;
DR   C3NH23, CARB_SULIN ;  C3NEM0, CARB_SULIY ;  Q59969, CARB_SULSO ;
DR   Q970U7, CARB_SULTO ;  Q67Q54, CARB_SYMTH ;  Q55756, CARB_SYNY3 ;
DR   Q9HK17, CARB_THEAC ;  A8F453, CARB_THELT ;  Q9WZ27, CARB_THEMA ;
DR   B9KB91, CARB_THENN ;  A5IJL8, CARB_THEP1 ;  B0KBW4, CARB_THEP3 ;
DR   B0K4D7, CARB_THEPX ;  B9KXM5, CARB_THERP ;  B1L8T8, CARB_THESQ ;
DR   P96495, CARB_THET2 ;  Q5SKN1, CARB_THET8 ;  Q8RBK0, CARB_THETN ;
DR   Q97AJ3, CARB_THEVO ;  P46056, CARB_TRICU ;  Q9KPH9, CARB_VIBCH ;
DR   Q87SF3, CARB_VIBPA ;  Q8DEM2, CARB_VIBVU ;  Q7MNU0, CARB_VIBVY ;
DR   P58942, CARB_XANAC ;  P58943, CARB_XANCP ;  Q9PEC1, CARB_XYLFA ;
DR   Q87EB8, CARB_XYLFT ;  P03965, CARB_YEAST ;  Q8ZIL4, CARB_YERPE ;
DR   O50236, CARB_ZYMMO ;  Q9K8V6, CARX_BACHD ;  P36838, CARX_BACSU ;
DR   P54324, CARX_GEOSE ;  O08317, CARX_LACPL ;  Q9K8V7, CARY_BACHD ;
DR   P18185, CARY_BACSU ;  Q9ZB63, CARY_GEOSE ;  Q9RLS9, CARY_LACPL ;
DR   P20054, PYR1_DICDI ;  P05990, PYR1_DROME ;  O93937, PYR1_EMENI ;
DR   P27708, PYR1_HUMAN ;  P08955, PYR1_MESAU ;  Q09794, PYR1_SCHPO ;
DR   Q91437, PYR1_SQUAC ;  P07259, PYR1_YEAST ;
//
ID   6.3.5.6
DE   Asparaginyl-tRNA synthase (glutamine-hydrolyzing).
AN   Asp-AdT.
AN   Asp-tRNA(Asn) amidotransferase.
AN   Aspartyl-tRNA(Asn) amidotransferase.
CA   ATP + aspartyl-tRNA(Asn) + L-glutamine = ADP + phosphate + asparaginyl-
CA   tRNA(Asn) + L-glutamate.
CC   -!- This reaction forms part of a two-reaction system for producing
CC       asparaginyl-tRNA in Deinococcus radiodurans and other organisms
CC       lacking a specific enzyme for asparagine synthesis.
CC   -!- In the first step, a non-discriminating ligase (EC 6.1.1.23)
CC       mischarges tRNA(Asn) with aspartate, leading to the formation of
CC       aspartyl-tRNA(Asn).
CC   -!- The aspartyl-tRNA(Asn) is not used in protein synthesis until the
CC       present enzyme converts it into asparaginyl-tRNA(Asn) (aspartyl-
CC       tRNA(Asp) is not a substrate for this reaction).
CC   -!- Ammonia or asparagine can substitute for the preferred substrate
CC       glutamine.
//
ID   6.3.5.7
DE   Glutaminyl-tRNA synthase (glutamine-hydrolyzing).
AN   Glu-AdT.
AN   Glu-tRNA(Gln) amidotransferase.
AN   Glutamyl-tRNA(Gln) amidotransferase.
CA   ATP + glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + glutaminyl-
CA   tRNA(Gln) + L-glutamate.
CC   -!- In systems lacking discernible EC 6.1.1.18, glutaminyl-tRNA(Gln) is
CC       formed by a two-enzyme system.
CC   -!- In the first step, a nondiscriminating ligase (EC 6.1.1.24)
CC       mischarges tRNA(Gln) with glutamate, forming glutamyl-tRNA(Gln).
CC   -!- The glutamyl-tRNA(Gln) is not used in protein synthesis until the
CC       present enzyme converts it into glutaminyl-tRNA(Gln) (glutamyl-
CC       tRNA(Glu) is not a substrate for this reaction).
CC   -!- Ammonia or asparagine can substitute for the preferred substrate
CC       glutamine.
PR   PROSITE; PDOC00948;
//
ID   6.3.5.8
DE   Transferred entry: 2.6.1.85.
//
ID   6.3.5.9
DE   Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing).
CA   2 ATP + hydrogenobyrinic acid + 2 L-glutamine + 2 H(2)O = 2 ADP +
CA   2 phosphate + hydrogenobyrinic acid a,c-diamide + 2 L-glutamate.
CC   -!- This step in the aerobic biosynthesis of cobalamin generates
CC       hydrogenobyrinic acid a,c-diamide, the substrate required by
CC       EC 6.6.1.2, which adds cobalt to the macrocycle.
//
ID   6.3.5.10
DE   Adenosylcobyric acid synthase (glutamine-hydrolyzing).
AN   5'-deoxy-5'-adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase.
AN   Ado-cobyric acid synthase (glutamine hydrolyzing).
AN   Cobyric acid synthase.
CA   4 ATP + adenosylcobyrinic acid a,c-diamide + 4 L-glutamine + 4 H(2)O =
CA   4 ADP + 4 phosphate + adenosylcobyric acid + 4 L-glutamate.
CF   Magnesium.
CC   -!- NH(3) can act instead of glutamine.
CC   -!- This enzyme catalyzes the four-step amidation sequence from cobyrinic
CC       acid a,c-diamide to cobyric acid via the formation of cobyrinic acid
CC       triamide, tetraamide and pentaamide intermediates.
//
ID   6.3.5.11
DE   Cobyrinate a,c-diamide synthase (glutamine-hydrolyzing).
AN   Cobyrinic acid a,c-diamide synthetase.
CA   2 ATP + cobyrinate + 2 L-glutamine + 2 H(2)O = 2 ADP + 2 phosphate +
CA   cobyrinate a,c-diamide + 2 L-glutamate.
CC   -!- This enzyme is the first glutamine amidotransferase that participates
CC       in the anaerobic (early cobalt insertion) biosynthetic pathway of
CC       adenosylcobalamin, and catalyzes the ATP-dependent synthesis of
CC       cobyrinate a,c-diamide from cobyrinate using either L-glutamine or
CC       ammonia as the nitrogen source.
CC   -!- It is proposed that the enzyme first catalyzes the amidation of the
CC       c-carboxylate, and then the intermediate is released into solution
CC       and binds to the same catalytic site for the amidation of the
CC       a-carboxylate.
CC   -!- The Km for ammonia is substantially higher than that for L-glutamine.
//
ID   6.4.1.1
DE   Pyruvate carboxylase.
AN   Pyruvic carboxylase.
CA   ATP + pyruvate + HCO(3)(-) = ADP + phosphate + oxaloacetate.
CF   Biotin; Zinc or manganese.
CC   -!- The animal enzyme requires acetyl-CoA.
PR   PROSITE; PDOC00167;
PR   PROSITE; PDOC00676;
PR   PROSITE; PDOC50975;
PR   PROSITE; PDOC50979;
PR   PROSITE; PDOC50991;
DR   O17732, PYC1_CAEEL ;  P11154, PYC1_YEAST ;  P32327, PYC2_YEAST ;
DR   O30019, PYCA_ARCFU ;  Q58626, PYCA_METJA ;  O27939, PYCA_METTH ;
DR   Q58628, PYCB_METJA ;  O27179, PYCB_METTH ;  Q9HES8, PYC_ASPNG  ;
DR   O93918, PYC_ASPTE  ;  Q0CLK1, PYC_ASPTN  ;  Q9KWU4, PYC_BACSU  ;
DR   Q29RK2, PYC_BOVIN  ;  P11498, PYC_HUMAN  ;  Q05920, PYC_MOUSE  ;
DR   Q8X1T3, PYC_PICAN  ;  P78992, PYC_PICPA  ;  P52873, PYC_RAT    ;
DR   Q9UUE1, PYC_SCHPO  ;
//
ID   6.4.1.2
DE   Acetyl-CoA carboxylase.
CA   ATP + acetyl-CoA + HCO(3)(-) = ADP + phosphate + malonyl-CoA.
CF   Biotin.
CC   -!- Also catalyzes transcarboxylation; the plant enzyme also carboxylates
CC       propanoyl-CoA and butanoyl-CoA.
PR   PROSITE; PDOC00167;
PR   PROSITE; PDOC00676;
PR   PROSITE; PDOC50979;
PR   PROSITE; PDOC50980;
DR   Q9TTS3, ACACA_BOVIN;  Q13085, ACACA_HUMAN;  Q5SWU9, ACACA_MOUSE;
DR   P11497, ACACA_RAT  ;  Q28559, ACACA_SHEEP;  O00763, ACACB_HUMAN;
DR   P85438, ACAC_CATRO ;  P11029, ACAC_CHICK ;  Q54J08, ACAC_DICDI ;
DR   P78820, ACAC_SCHPO ;  Q00955, ACAC_YEAST ;  Q38970, ACC1_ARATH ;
DR   Q8S6N5, ACC1_ORYSJ ;  F4I1L3, ACC2_ARATH ;  B9FK36, ACC2_ORYSJ ;
DR   B0CF67, ACCA_ACAM1 ;  B7GZY9, ACCA_ACIB3 ;  B7I6A3, ACCA_ACIB5 ;
DR   B2HTI7, ACCA_ACIBC ;  B0VV78, ACCA_ACIBS ;  A3M2B3, ACCA_ACIBT ;
DR   B0V5P9, ACCA_ACIBY ;  A5G0K5, ACCA_ACICJ ;  B7JA39, ACCA_ACIF2 ;
DR   B5EQR6, ACCA_ACIF5 ;  A3N2D4, ACCA_ACTP2 ;  B3H2H3, ACCA_ACTP7 ;
DR   B0BR78, ACCA_ACTPJ ;  A6VNE6, ACCA_ACTSZ ;  B9JBU0, ACCA_AGRRK ;
DR   Q8U9U5, ACCA_AGRT5 ;  Q0VQE1, ACCA_ALCBS ;  Q0A7K0, ACCA_ALHEH ;
DR   B6EJW4, ACCA_ALISL ;  A8MLP2, ACCA_ALKOO ;  Q3MA36, ACCA_ANAVT ;
DR   B7GGT0, ACCA_ANOFW ;  P46316, ACCA_ANTSP ;  O67260, ACCA_AQUAE ;
DR   Q9LD43, ACCA_ARATH ;  A8EWE9, ACCA_ARCB4 ;  Q5P2J0, ACCA_AROAE ;
DR   A8IHS4, ACCA_AZOC5 ;  A1K3X7, ACCA_AZOSB ;  C1DST0, ACCA_AZOVD ;
DR   A7Z7K7, ACCA_BACA2 ;  C3PAI9, ACCA_BACAA ;  C3L8X9, ACCA_BACAC ;
DR   A0RJJ7, ACCA_BACAH ;  Q81KY9, ACCA_BACAN ;  B7JRX3, ACCA_BACC0 ;
DR   B7IJZ9, ACCA_BACC2 ;  C1EUU4, ACCA_BACC3 ;  B7HFB4, ACCA_BACC4 ;
DR   B7HRP0, ACCA_BACC7 ;  A7GTP5, ACCA_BACCN ;  B9J0A0, ACCA_BACCQ ;
DR   Q817F2, ACCA_BACCR ;  Q633J7, ACCA_BACCZ ;  Q9K842, ACCA_BACHD ;
DR   Q6HCT2, ACCA_BACHK ;  Q65G81, ACCA_BACLD ;  Q5WEF5, ACCA_BACSK ;
DR   O34847, ACCA_BACSU ;  A1UQX6, ACCA_BARBK ;  A9IZR9, ACCA_BART1 ;
DR   Q1LSU5, ACCA_BAUCH ;  B2IKU6, ACCA_BEII9 ;  Q7VRD0, ACCA_BLOFL ;
DR   Q493B6, ACCA_BLOPB ;  Q2KX40, ACCA_BORA1 ;  Q7WLK8, ACCA_BORBR ;
DR   Q7W860, ACCA_BORPA ;  Q7VX94, ACCA_BORPE ;  A5ETC9, ACCA_BRASB ;
DR   A4YKW6, ACCA_BRASO ;  B2S8T2, ACCA_BRUA1 ;  Q57AM5, ACCA_BRUAB ;
DR   A9M9B7, ACCA_BRUC2 ;  C0RFS3, ACCA_BRUMB ;  Q8YJP3, ACCA_BRUME ;
DR   A5VSZ7, ACCA_BRUO2 ;  B0CJD4, ACCA_BRUSI ;  Q8FY57, ACCA_BRUSU ;
DR   B1YSM6, ACCA_BURA4 ;  Q1BHN9, ACCA_BURCA ;  B1JUK6, ACCA_BURCC ;
DR   A0K8K0, ACCA_BURCH ;  B4ED71, ACCA_BURCJ ;  Q0BDV6, ACCA_BURCM ;
DR   A9AHN8, ACCA_BURM1 ;  A3ML41, ACCA_BURM7 ;  A2SAY0, ACCA_BURM9 ;
DR   Q62J39, ACCA_BURMA ;  A1V5G6, ACCA_BURMS ;  A3NWX6, ACCA_BURP0 ;
DR   Q3JQT8, ACCA_BURP1 ;  A3NB48, ACCA_BURP6 ;  B2JIR9, ACCA_BURP8 ;
DR   B2SXP7, ACCA_BURPP ;  Q63ST0, ACCA_BURPS ;  Q39EZ0, ACCA_BURS3 ;
DR   A4JFC8, ACCA_BURVG ;  Q13X62, ACCA_BURXL ;  A7ZF35, ACCA_CAMC1 ;
DR   A7GWR2, ACCA_CAMC5 ;  A0RQM4, ACCA_CAMFF ;  A7HZZ3, ACCA_CAMHC ;
DR   A8FKN0, ACCA_CAMJ8 ;  A7H4T6, ACCA_CAMJD ;  Q9PI62, ACCA_CAMJE ;
DR   A1VYG1, ACCA_CAMJJ ;  Q5HW21, ACCA_CAMJR ;  B9KF15, ACCA_CAMLR ;
DR   Q3ACZ7, ACCA_CARHZ ;  B8H2N7, ACCA_CAUCN ;  Q9A448, ACCA_CAUCR ;
DR   B0T8G4, ACCA_CAUSK ;  B3PBR5, ACCA_CELJU ;  Q5L6A8, ACCA_CHLAB ;
DR   Q3ATN9, ACCA_CHLCH ;  Q823M8, ACCA_CHLCV ;  Q253Y8, ACCA_CHLFF ;
DR   B3EER8, ACCA_CHLL2 ;  Q9PKC9, ACCA_CHLMU ;  B3QQR6, ACCA_CHLP8 ;
DR   B3EL67, ACCA_CHLPB ;  A1BD29, ACCA_CHLPD ;  Q9Z8C9, ACCA_CHLPN ;
DR   B0B7I1, ACCA_CHLT2 ;  Q3KM97, ACCA_CHLTA ;  B0BBP6, ACCA_CHLTB ;
DR   Q8KG09, ACCA_CHLTE ;  O84267, ACCA_CHLTR ;  Q1R017, ACCA_CHRSD ;
DR   Q7NT71, ACCA_CHRVO ;  A8ALA3, ACCA_CITK8 ;  Q97DB2, ACCA_CLOAB ;
DR   A6LSD1, ACCA_CLOB8 ;  B2V3S7, ACCA_CLOBA ;  B2THL2, ACCA_CLOBB ;
DR   B8I942, ACCA_CLOCE ;  Q0TRG2, ACCA_CLOP1 ;  Q8XLG5, ACCA_CLOPE ;
DR   Q0STU1, ACCA_CLOPS ;  Q485F2, ACCA_COLP3 ;  B6J4K5, ACCA_COXB1 ;
DR   B6IYZ2, ACCA_COXB2 ;  A9KF93, ACCA_COXBN ;  A9N949, ACCA_COXBR ;
DR   Q83BJ8, ACCA_COXBU ;  Q0KCA7, ACCA_CUPNH ;  Q473D1, ACCA_CUPPJ ;
DR   B3R4D3, ACCA_CUPTR ;  B1WPW6, ACCA_CYAA5 ;  O19903, ACCA_CYACA ;
DR   Q85G50, ACCA_CYAME ;  B8HSZ5, ACCA_CYAP4 ;  B7JZP4, ACCA_CYAP8 ;
DR   Q47HT1, ACCA_DECAR ;  Q9RV16, ACCA_DEIRA ;  B8FTK8, ACCA_DESHD ;
DR   Q24XY7, ACCA_DESHY ;  A5EXQ5, ACCA_DICNV ;  A7ZHS5, ACCA_ECO24 ;
DR   B7UJ86, ACCA_ECO27 ;  B7MBG6, ACCA_ECO45 ;  B7LGP7, ACCA_ECO55 ;
DR   P0ABD6, ACCA_ECO57 ;  B5Z0G4, ACCA_ECO5E ;  B7NIE7, ACCA_ECO7I ;
DR   B7MP45, ACCA_ECO81 ;  B7M1Y8, ACCA_ECO8A ;  C4ZRS7, ACCA_ECOBW ;
DR   B1XD54, ACCA_ECODH ;  A7ZWD1, ACCA_ECOHS ;  A1A7M9, ACCA_ECOK1 ;
DR   Q0TLE8, ACCA_ECOL5 ;  Q8FL03, ACCA_ECOL6 ;  B1IQF6, ACCA_ECOLC ;
DR   P0ABD5, ACCA_ECOLI ;  B7N852, ACCA_ECOLU ;  B6HZF9, ACCA_ECOSE ;
DR   B1LGY7, ACCA_ECOSM ;  Q1RG04, ACCA_ECOUT ;  C5B7S4, ACCA_EDWI9 ;
DR   A4W6T0, ACCA_ENT38 ;  Q830B5, ACCA_ENTFA ;  A7MEM7, ACCA_ENTS8 ;
DR   Q6D8C7, ACCA_ERWCT ;  B2VHY2, ACCA_ERWT9 ;  Q2NB51, ACCA_ERYLH ;
DR   B7LW64, ACCA_ESCF3 ;  B1YKB2, ACCA_EXIS2 ;  A5FNY7, ACCA_FLAJ1 ;
DR   A6GX95, ACCA_FLAPJ ;  B0TXA0, ACCA_FRAP2 ;  Q14GB2, ACCA_FRAT1 ;
DR   A7N9Y7, ACCA_FRATF ;  Q2A5B4, ACCA_FRATH ;  B2SEQ7, ACCA_FRATM ;
DR   A0Q808, ACCA_FRATN ;  Q0BNM6, ACCA_FRATO ;  Q5NEV9, ACCA_FRATT ;
DR   A4IXL3, ACCA_FRATW ;  Q8RG99, ACCA_FUSNN ;  C1A6B8, ACCA_GEMAT ;
DR   Q5KWB0, ACCA_GEOKA ;  Q39WC1, ACCA_GEOMG ;  Q74DB5, ACCA_GEOSL ;
DR   C5D664, ACCA_GEOSW ;  A4IRQ6, ACCA_GEOTN ;  Q7NCW2, ACCA_GLOVI ;
DR   A9HL57, ACCA_GLUDA ;  A0LYY6, ACCA_GRAFK ;  Q6B8M3, ACCA_GRATL ;
DR   Q7VPL3, ACCA_HAEDU ;  Q4QND7, ACCA_HAEI8 ;  A5UA82, ACCA_HAEIE ;
DR   P43872, ACCA_HAEIN ;  B8F892, ACCA_HAEPS ;  Q0I3D3, ACCA_HAES1 ;
DR   B0UUD1, ACCA_HAES2 ;  A1WWZ8, ACCA_HALHL ;  Q17XQ8, ACCA_HELAH ;
DR   Q7VI82, ACCA_HELHP ;  B0TI32, ACCA_HELMI ;  B6JLE0, ACCA_HELP2 ;
DR   B5Z6S9, ACCA_HELPG ;  Q1CTX0, ACCA_HELPH ;  Q9ZLS3, ACCA_HELPJ ;
DR   B2UTS1, ACCA_HELPS ;  O25283, ACCA_HELPY ;  Q5QZP1, ACCA_IDILO ;
DR   Q28V72, ACCA_JANSC ;  B5Y1I6, ACCA_KLEP3 ;  A6T4Y7, ACCA_KLEP7 ;
DR   C1D531, ACCA_LARHH ;  Q5X6W5, ACCA_LEGPA ;  A5IGC4, ACCA_LEGPC ;
DR   Q5ZXE6, ACCA_LEGPH ;  Q5WYB5, ACCA_LEGPL ;  Q92BE3, ACCA_LISIN ;
DR   C1KVL9, ACCA_LISMC ;  Q71Z95, ACCA_LISMF ;  B8DHH5, ACCA_LISMH ;
DR   Q8Y6V9, ACCA_LISMO ;  A0AJ21, ACCA_LISW6 ;  Q2VZG7, ACCA_MAGSA ;
DR   Q65UI5, ACCA_MANSM ;  A1TZ44, ACCA_MARAV ;  A6VUT8, ACCA_MARMS ;
DR   Q11DU2, ACCA_MESSB ;  Q607F6, ACCA_METCA ;  B8ID69, ACCA_METNO ;
DR   B0UBU9, ACCA_METS4 ;  Q5F8F5, ACCA_NEIG1 ;  B4RLH9, ACCA_NEIG2 ;
DR   A9LZ61, ACCA_NEIM0 ;  Q9JUF0, ACCA_NEIMA ;  Q9JRV8, ACCA_NEIMB ;
DR   A1KTZ4, ACCA_NEIMF ;  Q0ADH1, ACCA_NITEC ;  Q82VP5, ACCA_NITEU ;
DR   Q1QQX0, ACCA_NITHX ;  Q2Y814, ACCA_NITMU ;  A6Q1S1, ACCA_NITSB ;
DR   Q3SVN2, ACCA_NITWN ;  B2J1L9, ACCA_NOSP7 ;  Q8YLL3, ACCA_NOSS1 ;
DR   Q8EPD5, ACCA_OCEIH ;  A6WXC3, ACCA_OCHA4 ;  B6JAC0, ACCA_OLICO ;
DR   A1B4I6, ACCA_PARDP ;  A7HTW0, ACCA_PARL1 ;  Q6MC11, ACCA_PARUW ;
DR   Q9CNX9, ACCA_PASMU ;  Q41008, ACCA_PEA   ;  C6DAJ9, ACCA_PECCP ;
DR   Q3A585, ACCA_PELCD ;  Q3B1I3, ACCA_PELLD ;  B4SG04, ACCA_PELPB ;
DR   Q4FNA6, ACCA_PELUB ;  B4RG38, ACCA_PHEZH ;  Q7N8N1, ACCA_PHOLL ;
DR   Q6LN40, ACCA_PHOPR ;  B1XUY6, ACCA_POLNS ;  A4SX64, ACCA_POLSQ ;
DR   P51371, ACCA_PORPU ;  Q1XDB6, ACCA_PORYE ;  B4S4A3, ACCA_PROA2 ;
DR   A3PBQ8, ACCA_PROM0 ;  A2C0Z2, ACCA_PROM1 ;  A8G3P9, ACCA_PROM2 ;
DR   A2C7S3, ACCA_PROM3 ;  A9BEF8, ACCA_PROM4 ;  A2BVJ6, ACCA_PROM5 ;
DR   Q31C00, ACCA_PROM9 ;  Q7VD49, ACCA_PROMA ;  Q7V6D6, ACCA_PROMM ;
DR   Q7V2E6, ACCA_PROMP ;  A2BQ15, ACCA_PROMS ;  Q46GP3, ACCA_PROMT ;
DR   A4SGK0, ACCA_PROVI ;  Q48F75, ACCA_PSE14 ;  Q15WE7, ACCA_PSEA6 ;
DR   A6V1E9, ACCA_PSEA7 ;  B7V7U9, ACCA_PSEA8 ;  Q02RB1, ACCA_PSEAB ;
DR   Q9HXZ2, ACCA_PSEAE ;  Q1I642, ACCA_PSEE4 ;  Q4KHG0, ACCA_PSEF5 ;
DR   C3K6H2, ACCA_PSEFS ;  Q3IIX1, ACCA_PSEHT ;  Q3KH96, ACCA_PSEPF ;
DR   Q88MG4, ACCA_PSEPK ;  Q886M7, ACCA_PSESM ;  Q4ZWR2, ACCA_PSEU2 ;
DR   A4VJT7, ACCA_PSEU5 ;  Q1LPF3, ACCA_RALME ;  B2U9Q0, ACCA_RALPJ ;
DR   Q8Y075, ACCA_RALSO ;  B3PPF4, ACCA_RHIE6 ;  Q2K3L0, ACCA_RHIEC ;
DR   Q1MB43, ACCA_RHIL3 ;  Q98FX7, ACCA_RHILO ;  B5ZSI8, ACCA_RHILW ;
DR   Q92ME2, ACCA_RHIME ;  C3MHX3, ACCA_RHISN ;  Q7TTY7, ACCA_RHOBA ;
DR   B6IUW3, ACCA_RHOCS ;  Q2J2R7, ACCA_RHOP2 ;  Q07VD3, ACCA_RHOP5 ;
DR   Q6NCG4, ACCA_RHOPA ;  A3PGR9, ACCA_RHOS1 ;  Q3J5L4, ACCA_RHOS4 ;
DR   A4WVF3, ACCA_RHOS5 ;  Q16BI0, ACCA_ROSDO ;  Q1AU97, ACCA_RUBXD ;
DR   A1AVG1, ACCA_RUTMC ;  Q21LR0, ACCA_SACD2 ;  B5F8U6, ACCA_SALA4 ;
DR   A9MPH6, ACCA_SALAR ;  Q57T23, ACCA_SALCH ;  B5FJ32, ACCA_SALDC ;
DR   B5R424, ACCA_SALEP ;  B5R5I8, ACCA_SALG2 ;  B4TK60, ACCA_SALHS ;
DR   B4SV14, ACCA_SALNS ;  Q5PD69, ACCA_SALPA ;  A9N0T5, ACCA_SALPB ;
DR   C0Q6K8, ACCA_SALPC ;  B5BAP2, ACCA_SALPK ;  B4TYE5, ACCA_SALSV ;
DR   P0A1C4, ACCA_SALTI ;  P0A1C3, ACCA_SALTY ;  A8GID0, ACCA_SERP5 ;
DR   B2U328, ACCA_SHIB3 ;  Q325V5, ACCA_SHIBS ;  Q32JS4, ACCA_SHIDS ;
DR   Q0T824, ACCA_SHIF8 ;  P0ABD7, ACCA_SHIFL ;  Q3Z5H3, ACCA_SHISS ;
DR   Q5LME7, ACCA_SILPO ;  A6UCL8, ACCA_SINMW ;  Q2NRM3, ACCA_SODGM ;
DR   A9F596, ACCA_SORC5 ;  Q1GS64, ACCA_SPHAL ;  A5V3X0, ACCA_SPHWW ;
DR   A7X3C7, ACCA_STAA1 ;  A6U2G6, ACCA_STAA2 ;  Q2FG38, ACCA_STAA3 ;
DR   Q2FXM7, ACCA_STAA8 ;  A5ITM3, ACCA_STAA9 ;  Q2YTE1, ACCA_STAAB ;
DR   Q5HF74, ACCA_STAAC ;  A6QHN4, ACCA_STAAE ;  Q99TG3, ACCA_STAAM ;
DR   Q7A558, ACCA_STAAN ;  Q6GG07, ACCA_STAAR ;  Q6G8M7, ACCA_STAAS ;
DR   A8Z2L5, ACCA_STAAT ;  Q8NW60, ACCA_STAAW ;  B9DN95, ACCA_STACT ;
DR   Q5HNK5, ACCA_STAEQ ;  Q8CS67, ACCA_STAES ;  Q4L741, ACCA_STAHJ ;
DR   Q49YC9, ACCA_STAS1 ;  C0M857, ACCA_STRE4 ;  B4U1C2, ACCA_STREM ;
DR   A8AYV4, ACCA_STRGC ;  B4SQ06, ACCA_STRM5 ;  B2FHN1, ACCA_STRMK ;
DR   Q04M48, ACCA_STRP2 ;  B5E1P0, ACCA_STRP4 ;  C1C5G4, ACCA_STRP7 ;
DR   Q1JA98, ACCA_STRPB ;  Q1JKF0, ACCA_STRPC ;  Q1JFE3, ACCA_STRPD ;
DR   Q1J593, ACCA_STRPF ;  A2RCY0, ACCA_STRPG ;  B1I9M1, ACCA_STRPI ;
DR   B8ZLJ3, ACCA_STRPJ ;  Q9FBB7, ACCA_STRPN ;  B2ILX2, ACCA_STRPS ;
DR   B5XHX5, ACCA_STRPZ ;  Q8DR13, ACCA_STRR6 ;  C0ME08, ACCA_STRS7 ;
DR   A3CQ50, ACCA_STRSV ;  Q5M174, ACCA_STRT1 ;  Q5M5R1, ACCA_STRT2 ;
DR   Q03M45, ACCA_STRTD ;  B9DVD9, ACCA_STRU0 ;  C1CCJ2, ACCA_STRZJ ;
DR   C1CIS8, ACCA_STRZP ;  C1CPT7, ACCA_STRZT ;  Q30Q46, ACCA_SULDN ;
DR   A6QC95, ACCA_SULNB ;  Q54766, ACCA_SYNE7 ;  B1XK66, ACCA_SYNP2 ;
DR   Q5N625, ACCA_SYNP6 ;  A5GJG7, ACCA_SYNPW ;  Q7U5H1, ACCA_SYNPX ;
DR   Q0I8N1, ACCA_SYNS3 ;  Q3AV54, ACCA_SYNS9 ;  Q3ALN0, ACCA_SYNSC ;
DR   Q0AVW1, ACCA_SYNWW ;  P74638, ACCA_SYNY3 ;  C5BR01, ACCA_TERTT ;
DR   Q8DJB6, ACCA_THEEB ;  Q72HS8, ACCA_THET2 ;  Q5SHG3, ACCA_THET8 ;
DR   B5YIK7, ACCA_THEYD ;  Q31G64, ACCA_THICR ;  Q3SL76, ACCA_THIDA ;
DR   B8GQ68, ACCA_THISH ;  C4L848, ACCA_TOLAT ;  Q73Q55, ACCA_TREDE ;
DR   Q117H3, ACCA_TRIEI ;  B1GZT6, ACCA_UNCTG ;  A5CXS3, ACCA_VESOH ;
DR   A5F624, ACCA_VIBC3 ;  Q9KPW8, ACCA_VIBCH ;  C3LPP8, ACCA_VIBCM ;
DR   Q5E3F5, ACCA_VIBF1 ;  B5F9W0, ACCA_VIBFM ;  A7MXZ9, ACCA_VIBHB ;
DR   Q87MF3, ACCA_VIBPA ;  B7VIQ2, ACCA_VIBSL ;  Q8DBE5, ACCA_VIBVU ;
DR   Q7MIH6, ACCA_VIBVY ;  Q8D2H6, ACCA_WIGBR ;  Q7M9W3, ACCA_WOLSU ;
DR   Q8PMM1, ACCA_XANAC ;  Q3BVM0, ACCA_XANC5 ;  Q4USP4, ACCA_XANC8 ;
DR   B0RW82, ACCA_XANCB ;  Q8PAW9, ACCA_XANCP ;  Q2P4C1, ACCA_XANOM ;
DR   B2SR15, ACCA_XANOP ;  Q5H1F6, ACCA_XANOR ;  A7ICM4, ACCA_XANP2 ;
DR   B2I6R7, ACCA_XYLF2 ;  Q9PGU5, ACCA_XYLFA ;  B0U1N1, ACCA_XYLFM ;
DR   Q87EY1, ACCA_XYLFT ;  A1JP64, ACCA_YERE8 ;  A7FFI5, ACCA_YERP3 ;
DR   Q1CAL8, ACCA_YERPA ;  B2JZ18, ACCA_YERPB ;  Q8ZH52, ACCA_YERPE ;
DR   A9R380, ACCA_YERPG ;  Q1CFG3, ACCA_YERPN ;  A4TL75, ACCA_YERPP ;
DR   Q667K5, ACCA_YERPS ;  B1JQH6, ACCA_YERPY ;  Q5NPY2, ACCA_ZYMMO ;
DR   P49787, ACCC1_BACSU;  B9HBA8, ACCC1_POPTR;  O34544, ACCC2_BACSU;
DR   B9N843, ACCC2_POPTR;  O52058, ACCC_ALLVD ;  O04983, ACCC_ARATH ;
DR   Q9KDS9, ACCC_BACHD ;  Q8X9B6, ACCC_ECO57 ;  P24182, ACCC_ECOLI ;
DR   P43873, ACCC_HAEIN ;  Q06862, ACCC_NOSS1 ;  P84546, ACCC_POPEU ;
DR   P37798, ACCC_PSEAE ;  C4Z3C6, ACCD1_EUBE2;  C6VLJ0, ACCD1_LACPJ;
DR   Q88YZ2, ACCD1_LACPL;  B1HNE3, ACCD1_LYSSC;  A7NIE9, ACCD1_ROSCS;
DR   A5UQC0, ACCD1_ROSS1;  A7MS74, ACCD1_VIBHB;  Q87MP2, ACCD1_VIBPA;
DR   C4Z630, ACCD2_EUBE2;  C6VQ34, ACCD2_LACPJ;  Q88WG0, ACCD2_LACPL;
DR   B1HX17, ACCD2_LYSSC;  A7NN57, ACCD2_ROSCS;  A5UY57, ACCD2_ROSS1;
DR   A7N581, ACCD2_VIBHB;  Q87I11, ACCD2_VIBPA;  Q899N5, ACCDA_CLOTE;
DR   C4Z8P1, ACCDA_EUBR3;  Q0RKW5, ACCDA_FRAAA;  Q2J8V6, ACCDA_FRASC;
DR   A8L4H3, ACCDA_FRASN;  B2A865, ACCDA_NATTJ;  A4F5Q5, ACCDA_SACEN;
DR   A8M4V8, ACCDA_SALAI;  A4X7V1, ACCDA_SALTO;  B0C728, ACCD_ACAM1 ;
DR   A9NFE8, ACCD_ACHLI ;  Q6FEE5, ACCD_ACIAD ;  B7GWQ6, ACCD_ACIB3 ;
DR   B7I8K1, ACCD_ACIB5 ;  B2HYI9, ACCD_ACIBC ;  B0VRF9, ACCD_ACIBS ;
DR   A3M8N1, ACCD_ACIBT ;  B0V530, ACCD_ACIBY ;  A3MZZ7, ACCD_ACTP2 ;
DR   B3H159, ACCD_ACTP7 ;  B0BNR1, ACCD_ACTPJ ;  A6VP44, ACCD_ACTSZ ;
DR   Q85FL3, ACCD_ADICA ;  A0KLN6, ACCD_AERHH ;  A4SNT7, ACCD_AERS4 ;
DR   A4QJC4, ACCD_AETCO ;  A4QJK8, ACCD_AETGR ;  B9JG45, ACCD_AGRRK ;
DR   A9CKT0, ACCD_AGRT5 ;  B9JXV8, ACCD_AGRVS ;  Q0VPJ1, ACCD_ALCBS ;
DR   Q0A9A0, ACCD_ALHEH ;  A8MLP1, ACCD_ALKOO ;  B4RUR0, ACCD_ALTMD ;
DR   Q70XZ4, ACCD_AMBTC ;  B3EU20, ACCD_AMOA5 ;  Q3MGS5, ACCD_ANAVT ;
DR   P28252, ACCD_ANGLY ;  B7GGS9, ACCD_ANOFW ;  Q31796, ACCD_ANTFO ;
DR   A4QK27, ACCD_ARAHI ;  P56765, ACCD_ARATH ;  Q8S8W7, ACCD_ATRBE ;
DR   A8HQ90, ACCD_AZOC5 ;  A7Z7K8, ACCD_BACA2 ;  C3PAJ0, ACCD_BACAA ;
DR   C3L8Y0, ACCD_BACAC ;  A0RJJ8, ACCD_BACAH ;  Q81KY8, ACCD_BACAN ;
DR   B7JRX4, ACCD_BACC0 ;  Q72ZD6, ACCD_BACC1 ;  B7IK00, ACCD_BACC2 ;
DR   C1EUU5, ACCD_BACC3 ;  B7HFB5, ACCD_BACC4 ;  B7HRP1, ACCD_BACC7 ;
DR   A7GTP6, ACCD_BACCN ;  B9J0A1, ACCD_BACCQ ;  Q817F1, ACCD_BACCR ;
DR   Q633J6, ACCD_BACCZ ;  Q9K841, ACCD_BACHD ;  Q6HCT1, ACCD_BACHK ;
DR   Q65G80, ACCD_BACLD ;  A8FG57, ACCD_BACP2 ;  Q5WEF4, ACCD_BACSK ;
DR   C0SP93, ACCD_BACSU ;  A9VJR3, ACCD_BACWK ;  A1UUE5, ACCD_BARBK ;
DR   C6AB58, ACCD_BARGA ;  Q6G581, ACCD_BARHE ;  Q6G1D3, ACCD_BARQU ;
DR   A9IL94, ACCD_BART1 ;  A4QKB4, ACCD_BARVE ;  Q1LTA5, ACCD_BAUCH ;
DR   B2IF45, ACCD_BEII9 ;  Q7VRV0, ACCD_BLOFL ;  Q492H4, ACCD_BLOPB ;
DR   Q89WE3, ACCD_BRAJA ;  P48937, ACCD_BRANA ;  A5E8A2, ACCD_BRASB ;
DR   A4YJI4, ACCD_BRASO ;  C0Z7W5, ACCD_BREBN ;  B2S9A2, ACCD_BRUA1 ;
DR   Q2YQW8, ACCD_BRUA2 ;  Q57AF3, ACCD_BRUAB ;  A9M9T9, ACCD_BRUC2 ;
DR   C0RFZ1, ACCD_BRUMB ;  Q8YE58, ACCD_BRUME ;  A5VT60, ACCD_BRUO2 ;
DR   B0CJK5, ACCD_BRUSI ;  Q8FXY7, ACCD_BRUSU ;  Q1BM67, ACCD_BURCA ;
DR   B4EFK3, ACCD_BURCJ ;  A9AMA4, ACCD_BURM1 ;  B2JQF1, ACCD_BURP8 ;
DR   A6MM45, ACCD_BUXMI ;  Q7YIX5, ACCD_CALFG ;  A4QKK1, ACCD_CAPBU ;
DR   Q3ACZ8, ACCD_CARHZ ;  B1A944, ACCD_CARPA ;  B8H660, ACCD_CAUCN ;
DR   Q9A2L5, ACCD_CAUCR ;  B0T695, ACCD_CAUSK ;  B3PFP1, ACCD_CELJU ;
DR   A8SEB2, ACCD_CERDE ;  A9WBQ9, ACCD_CHLAA ;  B8G381, ACCD_CHLAD ;
DR   Q3ATW0, ACCD_CHLCH ;  B3EFW3, ACCD_CHLL2 ;  B3QL38, ACCD_CHLP8 ;
DR   A1BI17, ACCD_CHLPD ;  A6MMD1, ACCD_CHLSC ;  B9LE80, ACCD_CHLSY ;
DR   Q8KC71, ACCD_CHLTE ;  P56293, ACCD_CHLVU ;  Q1QY40, ACCD_CHRSD ;
DR   B5LMN4, ACCD_CICAR ;  A8ADR3, ACCD_CITK8 ;  Q09MG9, ACCD_CITSI ;
DR   Q97DB1, ACCD_CLOAB ;  A7FPN5, ACCD_CLOB1 ;  C3KWE8, ACCD_CLOB6 ;
DR   A6LSD0, ACCD_CLOB8 ;  B2V3S6, ACCD_CLOBA ;  B2THL1, ACCD_CLOBB ;
DR   A5I7W9, ACCD_CLOBH ;  C1FNJ8, ACCD_CLOBJ ;  B1IH48, ACCD_CLOBK ;
DR   A7GJJ0, ACCD_CLOBL ;  B1KU65, ACCD_CLOBM ;  B8I941, ACCD_CLOCE ;
DR   Q187P6, ACCD_CLOD6 ;  B9DY13, ACCD_CLOK1 ;  A5N4F0, ACCD_CLOK5 ;
DR   A0PXC5, ACCD_CLONN ;  Q0TRG3, ACCD_CLOP1 ;  Q8XLG6, ACCD_CLOPE ;
DR   Q0STU2, ACCD_CLOPS ;  A0A344, ACCD_COFAR ;  Q47XK5, ACCD_COLP3 ;
DR   A9KFZ6, ACCD_COXBN ;  A9ND23, ACCD_COXBR ;  Q83D51, ACCD_COXBU ;
DR   A4QKU0, ACCD_CRUWA ;  B1VKF0, ACCD_CRYJA ;  Q2QD80, ACCD_CUCSA ;
DR   B3R112, ACCD_CUPTR ;  A7M907, ACCD_CUSGR ;  P31562, ACCD_CUSRE ;
DR   B1WNK3, ACCD_CYAA5 ;  Q9TLW3, ACCD_CYACA ;  Q0G9V3, ACCD_DAUCA ;
DR   Q47HQ3, ACCD_DECAR ;  B1I3G7, ACCD_DESAP ;  B8FTK7, ACCD_DESHD ;
DR   Q24XY8, ACCD_DESHY ;  A4J6X2, ACCD_DESRM ;  A8LKN7, ACCD_DINSH ;
DR   A6MML6, ACCD_DIOEL ;  A4QL28, ACCD_DRANE ;  Q06GY8, ACCD_DRIGR ;
DR   A7ZPD1, ACCD_ECO24 ;  P0A9Q6, ACCD_ECO57 ;  B1X927, ACCD_ECODH ;
DR   A8A2I5, ACCD_ECOHS ;  A1ADG5, ACCD_ECOK1 ;  Q0TFD0, ACCD_ECOL5 ;
DR   Q8FFH5, ACCD_ECOL6 ;  B1IXM6, ACCD_ECOLC ;  P0A9Q5, ACCD_ECOLI ;
DR   B1LLS1, ACCD_ECOSM ;  Q1R996, ACCD_ECOUT ;  A4WCV0, ACCD_ENT38 ;
DR   Q830B4, ACCD_ENTFA ;  A7MH52, ACCD_ENTS8 ;  P30064, ACCD_EPIVI ;
DR   Q6D2N9, ACCD_ERWCT ;  B2VJ00, ACCD_ERWT9 ;  Q2N9M9, ACCD_ERYLH ;
DR   Q49KY9, ACCD_EUCGG ;  B1YKB3, ACCD_EXIS2 ;  C4L481, ACCD_EXISA ;
DR   B2XWL4, ACCD_FAGEA ;  C6X3B5, ACCD_FLAB3 ;  A5FJY2, ACCD_FLAJ1 ;
DR   A6GWG2, ACCD_FLAPJ ;  Q8RGA0, ACCD_FUSNN ;  B5EAK5, ACCD_GEOBB ;
DR   Q5KWA9, ACCD_GEOKA ;  C5D665, ACCD_GEOSW ;  A4IRQ7, ACCD_GEOTN ;
DR   Q7NK73, ACCD_GLOVI ;  A9HE81, ACCD_GLUDA ;  Q5FRN1, ACCD_GLUOX ;
DR   A0ZZ44, ACCD_GOSBA ;  Q2L915, ACCD_GOSHI ;  Q0BQJ1, ACCD_GRABC ;
DR   A0LYC3, ACCD_GRAFK ;  B2LMK2, ACCD_GUIAB ;  Q7VLH8, ACCD_HAEDU ;
DR   Q4QJY5, ACCD_HAEI8 ;  A5UBS0, ACCD_HAEIE ;  A5UF50, ACCD_HAEIG ;
DR   P43778, ACCD_HAEIN ;  Q0I3I5, ACCD_HAES1 ;  B0UU81, ACCD_HAES2 ;
DR   Q2SJC9, ACCD_HAHCH ;  A1WY04, ACCD_HALHL ;  B8D1K3, ACCD_HALOH ;
DR   Q1KXV0, ACCD_HELAN ;  B0TI33, ACCD_HELMI ;  Q2EEX4, ACCD_HELSJ ;
DR   A9B536, ACCD_HERA2 ;  C6XMV9, ACCD_HIRBI ;  B4U8Q5, ACCD_HYDS0 ;
DR   Q0BWJ8, ACCD_HYPNA ;  Q5QUD9, ACCD_IDILO ;  A6MMV3, ACCD_ILLOL ;
DR   A7Y3E9, ACCD_IPOPU ;  Q28WD5, ACCD_JANSC ;  A6TC02, ACCD_KLEP7 ;
DR   Q03RW0, ACCD_LACBA ;  Q036L2, ACCD_LACC3 ;  B3W9I9, ACCD_LACCB ;
DR   Q1GAF3, ACCD_LACDA ;  Q04AU0, ACCD_LACDB ;  B2GAH2, ACCD_LACF3 ;
DR   A8YXR2, ACCD_LACH4 ;  Q9CHF2, ACCD_LACLA ;  A2RM23, ACCD_LACLM ;
DR   Q030J0, ACCD_LACLS ;  A5VK70, ACCD_LACRD ;  B2G7K3, ACCD_LACRJ ;
DR   Q1WUR6, ACCD_LACS1 ;  Q332W9, ACCD_LACSA ;  Q38XF6, ACCD_LACSS ;
DR   A9L9A5, ACCD_LEMMI ;  A4QLB5, ACCD_LEPVR ;  B1MX91, ACCD_LEUCK ;
DR   Q03ZC9, ACCD_LEUMM ;  C6XFZ0, ACCD_LIBAP ;  Q0G9L0, ACCD_LIRTU ;
DR   Q92BE2, ACCD_LISIN ;  C1KVM0, ACCD_LISMC ;  Q71Z94, ACCD_LISMF ;
DR   B8DHH4, ACCD_LISMH ;  Q8Y6V8, ACCD_LISMO ;  A0AJ22, ACCD_LISW6 ;
DR   A4QLK3, ACCD_LOBMA ;  Q9BBS1, ACCD_LOTJA ;  B9E7A6, ACCD_MACCJ ;
DR   Q65TC9, ACCD_MANSM ;  A1U0X1, ACCD_MARAV ;  Q0ATK2, ACCD_MARMM ;
DR   A6VWY7, ACCD_MARMS ;  P12217, ACCD_MARPO ;  Q11KL2, ACCD_MESSB ;
DR   B7KSK6, ACCD_METC4 ;  Q604P5, ACCD_METCA ;  C5ASN5, ACCD_METEA ;
DR   C7CMU4, ACCD_METED ;  A9VWE8, ACCD_METEP ;  Q1H0M3, ACCD_METFK ;
DR   B3DWQ9, ACCD_METI4 ;  B8IPW2, ACCD_METNO ;  B1ZLY6, ACCD_METPB ;
DR   B1LSQ7, ACCD_METRJ ;  B0UKV1, ACCD_METS4 ;  B8ESN3, ACCD_METSB ;
DR   B0JI13, ACCD_MICAN ;  Q09X08, ACCD_MORIN ;  P63406, ACCD_MYCBO ;
DR   P63405, ACCD_MYCTU ;  Q09FV2, ACCD_NANDO ;  A4QLU2, ACCD_NASOF ;
DR   Q3C1J3, ACCD_NICSY ;  Q33C25, ACCD_NICTO ;  Q1QS35, ACCD_NITHX ;
DR   Q3SWM0, ACCD_NITWN ;  B2IVE7, ACCD_NOSP7 ;  Q8YUI2, ACCD_NOSS1 ;
DR   Q2G8S9, ACCD_NOVAD ;  A1XFW4, ACCD_NUPAD ;  Q6EW70, ACCD_NYMAL ;
DR   Q8EPD4, ACCD_OCEIH ;  A6WX31, ACCD_OCHA4 ;  Q9MTL3, ACCD_OENEH ;
DR   Q04DN6, ACCD_OENOB ;  B6JCP4, ACCD_OLICO ;  A4QJU2, ACCD_OLIPU ;
DR   B1ZVD6, ACCD_OPITP ;  C6D8C0, ACCD_PAESJ ;  Q68RZ7, ACCD_PANGI ;
DR   Q6MEK6, ACCD_PARUW ;  Q9CN12, ACCD_PASMU ;  P18823, ACCD_PEA   ;
DR   C6XT67, ACCD_PEDHD ;  Q03FV0, ACCD_PEDPA ;  Q3A6L1, ACCD_PELCD ;
DR   Q3B5Y0, ACCD_PELLD ;  B4SEP9, ACCD_PELPB ;  A1AN64, ACCD_PELPD ;
DR   A5D014, ACCD_PELTS ;  Q4FND1, ACCD_PELUB ;  Q3BAN3, ACCD_PHAAO ;
DR   B4RCL2, ACCD_PHEZH ;  Q7N2B5, ACCD_PHOLL ;  Q6LNU6, ACCD_PHOPR ;
DR   Q00761, ACCD_PHYPA ;  O47039, ACCD_PICAB ;  Q85X25, ACCD_PINKO ;
DR   P52769, ACCD_PINTH ;  Q06GQ1, ACCD_PIPCE ;  Q09G37, ACCD_PLAOC ;
DR   Q14FE8, ACCD_POPAL ;  A4GYS0, ACCD_POPTR ;  P51198, ACCD_PORPU ;
DR   Q1XDT9, ACCD_PORYE ;  B4S459, ACCD_PROA2 ;  A3PCJ3, ACCD_PROM0 ;
DR   A2C1M1, ACCD_PROM1 ;  A8G4G3, ACCD_PROM2 ;  A2CAG3, ACCD_PROM3 ;
DR   A9BAP6, ACCD_PROM4 ;  A2BW45, ACCD_PROM5 ;  Q31B93, ACCD_PROM9 ;
DR   Q7VC83, ACCD_PROMA ;  B4EZF5, ACCD_PROMH ;  Q7V839, ACCD_PROMM ;
DR   Q7V1S1, ACCD_PROMP ;  A2BQS1, ACCD_PROMS ;  Q46LE5, ACCD_PROMT ;
DR   A4SD85, ACCD_PROVI ;  Q48L24, ACCD_PSE14 ;  Q15VG1, ACCD_PSEA6 ;
DR   A6V2W2, ACCD_PSEA7 ;  Q02PS5, ACCD_PSEAB ;  Q9HZA7, ACCD_PSEAE ;
DR   Q1ICS2, ACCD_PSEE4 ;  Q4KEZ8, ACCD_PSEF5 ;  Q3IF41, ACCD_PSEHT ;
DR   A4XVV4, ACCD_PSEMY ;  A5W6X9, ACCD_PSEP1 ;  Q3KF15, ACCD_PSEPF ;
DR   B0KF95, ACCD_PSEPG ;  Q88LD9, ACCD_PSEPK ;  B1J539, ACCD_PSEPW ;
DR   Q87YI2, ACCD_PSESM ;  Q4ZVW0, ACCD_PSEU2 ;  A4VKF5, ACCD_PSEU5 ;
DR   Q4FUL1, ACCD_PSYA2 ;  Q1QDK1, ACCD_PSYCK ;  A5WDG8, ACCD_PSYWF ;
DR   A1XGP7, ACCD_RANMC ;  B3PVV4, ACCD_RHIE6 ;  Q2KE80, ACCD_RHIEC ;
DR   Q1MND4, ACCD_RHIL3 ;  Q98CN5, ACCD_RHILO ;  C6B119, ACCD_RHILS ;
DR   B5ZV72, ACCD_RHILW ;  Q92TC7, ACCD_RHIME ;  C3MBA1, ACCD_RHISN ;
DR   Q7UHX0, ACCD_RHOBA ;  Q2J2G6, ACCD_RHOP2 ;  Q07UG9, ACCD_RHOP5 ;
DR   Q6NDN4, ACCD_RHOPA ;  Q21CC1, ACCD_RHOPB ;  Q13EQ0, ACCD_RHOPS ;
DR   B3Q607, ACCD_RHOPT ;  Q1AU96, ACCD_RUBXD ;  B5EZQ0, ACCD_SALA4 ;
DR   A9MJ59, ACCD_SALAR ;  Q57LY8, ACCD_SALCH ;  B5FPL0, ACCD_SALDC ;
DR   B5R347, ACCD_SALEP ;  B5RCJ1, ACCD_SALG2 ;  B4TBN5, ACCD_SALHS ;
DR   B4SZN8, ACCD_SALNS ;  Q5PCV4, ACCD_SALPA ;  A9N478, ACCD_SALPB ;
DR   B5BCI0, ACCD_SALPK ;  Q2S3F0, ACCD_SALRD ;  B4TQA2, ACCD_SALSV ;
DR   Q8XFJ5, ACCD_SALTI ;  Q7CQ41, ACCD_SALTY ;  A8GH40, ACCD_SERP5 ;
DR   B2TW98, ACCD_SHIB3 ;  Q31YE2, ACCD_SHIBS ;  Q32DM0, ACCD_SHIDS ;
DR   Q0T2G9, ACCD_SHIF8 ;  Q83KA2, ACCD_SHIFL ;  Q3YZP5, ACCD_SHISS ;
DR   A6UEI3, ACCD_SINMW ;  Q2NSI3, ACCD_SODGM ;  Q2MIH8, ACCD_SOLBU ;
DR   Q2MI91, ACCD_SOLLC ;  Q2VEG8, ACCD_SOLTU ;  A9G853, ACCD_SORC5 ;
DR   P49158, ACCD_SOYBN ;  Q9M3L7, ACCD_SPIOL ;  A7X3C8, ACCD_STAA1 ;
DR   A6U2G7, ACCD_STAA2 ;  Q2FG37, ACCD_STAA3 ;  Q2FXM6, ACCD_STAA8 ;
DR   A5ITM4, ACCD_STAA9 ;  Q2YTE0, ACCD_STAAB ;  Q5HF73, ACCD_STAAC ;
DR   A6QHN5, ACCD_STAAE ;  Q99TG2, ACCD_STAAM ;  Q7A557, ACCD_STAAN ;
DR   Q6GG06, ACCD_STAAR ;  Q6G8M6, ACCD_STAAS ;  A8Z2L6, ACCD_STAAT ;
DR   Q8NW59, ACCD_STAAW ;  B9DN96, ACCD_STACT ;  Q5HNK4, ACCD_STAEQ ;
DR   Q8CS66, ACCD_STAES ;  Q4L742, ACCD_STAHJ ;  Q49YD0, ACCD_STAS1 ;
DR   C5WIT0, ACCD_STRDG ;  C0M856, ACCD_STRE4 ;  B4U1C1, ACCD_STREM ;
DR   B4SQU5, ACCD_STRM5 ;  B2FNY8, ACCD_STRMK ;  C6SNX2, ACCD_STRMN ;
DR   Q99YE0, ACCD_STRP1 ;  P0CZ44, ACCD_STRP3 ;  Q5XAE9, ACCD_STRP6 ;
DR   Q8NZN5, ACCD_STRP8 ;  Q1JA97, ACCD_STRPB ;  Q1JKE9, ACCD_STRPC ;
DR   Q1JFE2, ACCD_STRPD ;  Q1J592, ACCD_STRPF ;  A2RCX9, ACCD_STRPG ;
DR   Q48RS6, ACCD_STRPM ;  P0CC08, ACCD_STRPN ;  P0CZ45, ACCD_STRPQ ;
DR   B5XHX6, ACCD_STRPZ ;  Q7CRB7, ACCD_STRR6 ;  A4W3M1, ACCD_STRS2 ;
DR   C6GWM7, ACCD_STRS4 ;  C0ME09, ACCD_STRS7 ;  C5VZW3, ACCD_STRSE ;
DR   A3CQ51, ACCD_STRSV ;  C6GN01, ACCD_STRSX ;  Q5M175, ACCD_STRT1 ;
DR   Q5M5R2, ACCD_STRT2 ;  Q03M46, ACCD_STRTD ;  B2V5V9, ACCD_SULSY ;
DR   Q54776, ACCD_SYNE7 ;  Q2JSX0, ACCD_SYNJA ;  Q2JIG8, ACCD_SYNJB ;
DR   B1XKV6, ACCD_SYNP2 ;  Q5N041, ACCD_SYNP6 ;  A5GKV9, ACCD_SYNPW ;
DR   Q7U836, ACCD_SYNPX ;  A5GSN7, ACCD_SYNR3 ;  Q0I9G1, ACCD_SYNS3 ;
DR   Q3AYR8, ACCD_SYNS9 ;  Q3AIH7, ACCD_SYNSC ;  Q0AVW0, ACCD_SYNWW ;
DR   Q57417, ACCD_SYNY3 ;  Q72HS7, ACCD_THET2 ;  Q5SHG2, ACCD_THET8 ;
DR   Q31HH2, ACCD_THICR ;  P12219, ACCD_TOBAC ;  Q73Q54, ACCD_TREDE ;
DR   Q111F1, ACCD_TRIEI ;  B1H0E3, ACCD_UNCTG ;  A5F2T5, ACCD_VIBC3 ;
DR   Q9KTA3, ACCD_VIBCH ;  Q5E456, ACCD_VIBF1 ;  B5FFN5, ACCD_VIBFM ;
DR   Q8DB33, ACCD_VIBVU ;  Q7MIU0, ACCD_VIBVY ;  Q0ZJ11, ACCD_VITVI ;
DR   Q8D2P4, ACCD_WIGBR ;  Q7MAM0, ACCD_WOLSU ;  Q8PJ30, ACCD_XANAC ;
DR   Q3BRL8, ACCD_XANC5 ;  Q4UWC9, ACCD_XANC8 ;  B0RR87, ACCD_XANCB ;
DR   Q8P7S1, ACCD_XANCP ;  Q2P0U4, ACCD_XANOM ;  B2SVN4, ACCD_XANOP ;
DR   Q5GXR7, ACCD_XANOR ;  A7IFZ8, ACCD_XANP2 ;  A1JL77, ACCD_YERE8 ;
DR   A7FGM3, ACCD_YERP3 ;  Q1C680, ACCD_YERPA ;  B2K8H3, ACCD_YERPB ;
DR   Q0WDC3, ACCD_YERPE ;  A9R7U5, ACCD_YERPG ;  Q1CHM2, ACCD_YERPN ;
DR   A4TM62, ACCD_YERPP ;  Q668X1, ACCD_YERPS ;  B1JGI4, ACCD_YERPY ;
DR   B3LM95, HFA1_YEAS1 ;  C7GRE4, HFA1_YEAS2 ;  A6ZMR9, HFA1_YEAS7 ;
DR   C8ZF72, HFA1_YEAS8 ;  P32874, HFA1_YEAST ;
//
ID   6.4.1.3
DE   Propionyl-CoA carboxylase.
AN   PCCase.
CA   ATP + propanoyl-CoA + HCO(3)(-) = ADP + phosphate + (S)-methylmalonyl-
CA   CoA.
CF   Biotin.
CC   -!- Also carboxylates butanoyl-CoA and catalyzes transcarboxylation.
PR   PROSITE; PDOC00167;
PR   PROSITE; PDOC00676;
PR   PROSITE; PDOC50975;
PR   PROSITE; PDOC50979;
PR   PROSITE; PDOC50980;
DR   P96885, PCC5_MYCTU ;  P63408, PCC6_MYCBO ;  P63407, PCC6_MYCTU ;
DR   Q612F5, PCCA_CAEBR ;  Q19842, PCCA_CAEEL ;  P05165, PCCA_HUMAN ;
DR   Q91ZA3, PCCA_MOUSE ;  P81185, PCCA_MYXXA ;  P14882, PCCA_RAT   ;
DR   P54541, PCCB_BACSU ;  Q2TBR0, PCCB_BOVIN ;  P05166, PCCB_HUMAN ;
DR   Q99MN9, PCCB_MOUSE ;  P53002, PCCB_MYCLE ;  P79384, PCCB_PIG   ;
DR   P07633, PCCB_RAT   ;  Q06101, PCCB_RHOER ;  P53003, PCCB_SACEN ;
//
ID   6.4.1.4
DE   Methylcrotonoyl-CoA carboxylase.
AN   Beta-methylcrotonyl-CoA carboxylase.
AN   Methylcrotonyl-CoA carboxylase.
CA   ATP + 3-methylcrotonoyl-CoA + HCO(3)(-) = ADP + phosphate +
CA   3-methylglutaconyl-CoA.
CF   Biotin.
PR   PROSITE; PDOC00167;
PR   PROSITE; PDOC50975;
PR   PROSITE; PDOC50979;
PR   PROSITE; PDOC50980;
DR   Q42523, MCCA_ARATH ;  Q54KE6, MCCA_DICDI ;  Q96RQ3, MCCA_HUMAN ;
DR   Q99MR8, MCCA_MOUSE ;  Q2QMG2, MCCA_ORYSJ ;  Q5I0C3, MCCA_RAT   ;
DR   Q42777, MCCA_SOYBN ;  Q9LDD8, MCCB_ARATH ;  P34385, MCCB_CAEEL ;
DR   Q8T2J9, MCCB_DICDI ;  Q9V9A7, MCCB_DROME ;  Q9HCC0, MCCB_HUMAN ;
DR   Q3ULD5, MCCB_MOUSE ;  Q5XIT9, MCCB_RAT   ;
//
ID   6.4.1.5
DE   Geranoyl-CoA carboxylase.
AN   Geranyl-CoA carboxylase.
CA   ATP + geranoyl-CoA + HCO(3)(-) = ADP + phosphate + 3-(4-methylpent-3-
CA   en-1-yl)pent-2-enedioyl-CoA.
CF   Biotin.
CC   -!- Also carboxylates dimethylpropenoyl-CoA and farnesoyl-CoA.
PR   PROSITE; PDOC00167;
//
ID   6.4.1.6
DE   Acetone carboxylase.
CA   Acetone + CO(2) + ATP + 2 H(2)O = acetoacetate + AMP + 2 phosphate.
CF   Magnesium.
CC   -!- The enzyme from Xanthobacter sp. strain Py2 also carboxylates butan-
CC       2-one to 3-oxopentanoate.
DR   Q8RM04, ACXA_XANP2 ;  Q8RM03, ACXB_XANP2 ;  Q8RM02, ACXC_XANP2 ;
//
ID   6.4.1.7
DE   2-oxoglutarate carboxylase.
AN   Carboxylating factor for ICDH.
AN   CFI.
AN   OGC.
AN   Oxalosuccinate synthetase.
CA   ATP + 2-oxoglutarate + HCO(3)(-) = ADP + phosphate + oxalosuccinate.
CF   Biotin; Magnesium.
CC   -!- It was originally thought that this enzyme was a promoting factor for
CC       the carboxylation of 2-oxoglutarate by EC 1.1.1.41, but this has
CC       since been disproved.
CC   -!- The product of the reaction is unstable and is quickly converted into
CC       isocitrate by the action of EC 1.1.1.41.
PR   PROSITE; PDOC00676;
PR   PROSITE; PDOC50975;
DR   D3DJ41, 2OCL_HYDTT ;  D3DJ42, 2OCS_HYDTT ;
//
ID   6.4.1.8
DE   Acetophenone carboxylase.
CA   2 ATP + acetophenone + HCO(3)(-) + H(2)O + H(+) = 2 ADP + 2 phosphate +
CA   3-oxo-3-phenylpropanoate.
CC   -!- The enzyme is involved in anaerobic degradation of ethylbenzene.
CC   -!- No activity with acetone, butanone, 4-hydroxy-acetophenone or
CC       4-amino-acetophenone.
//
ID   6.5.1.1
DE   DNA ligase (ATP).
AN   DNA joinase.
AN   DNA repair enzyme.
AN   Polydeoxyribonucleotide synthase (ATP).
AN   Polynucleotide ligase (ATP).
AN   Sealase.
CA   ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP +
CA   diphosphate + (deoxyribonucleotide)(n+m).
CC   -!- Catalyzes the formation of a phosphodiester at the site of a single-
CC       strand break in duplex DNA.
CC   -!- RNA can also act as substrate, to some extent.
PR   PROSITE; PDOC00295;
DR   Q42572, DNLI1_ARATH;  Q27474, DNLI1_CAEEL;  Q869E1, DNLI1_DICDI;
DR   Q9W1H4, DNLI1_DROME;  Q18HT7, DNLI1_HALWD;  P18858, DNLI1_HUMAN;
DR   B1L3K8, DNLI1_KORCO;  Q8TSR7, DNLI1_METAC;  Q46C04, DNLI1_METBF;
DR   Q8PVR7, DNLI1_METMA;  P37913, DNLI1_MOUSE;  Q9JHY8, DNLI1_RAT  ;
DR   P12000, DNLI1_SCHPO;  A1RXA6, DNLI1_THEPD;  P51892, DNLI1_XENLA;
DR   P04819, DNLI1_YEAST;  Q18GX5, DNLI2_HALWD;  B1L3V2, DNLI2_KORCO;
DR   Q8TMT1, DNLI2_METAC;  Q46BA3, DNLI2_METBF;  Q8PTK1, DNLI2_METMA;
DR   A1RY72, DNLI2_THEPD;  Q54QM4, DNLI3_DICDI;  P49916, DNLI3_HUMAN;
DR   P97386, DNLI3_MOUSE;  Q9C1W9, DNLI3_SCHPO;  Q9LL84, DNLI4_ARATH;
DR   Q75CA4, DNLI4_ASHGO;  Q4WVG8, DNLI4_ASPFU;  Q2U6A1, DNLI4_ASPOR;
DR   P52496, DNLI4_CANAL;  Q6FVD8, DNLI4_CANGA;  Q90YB1, DNLI4_CHICK;
DR   Q1DKE7, DNLI4_COCIM;  A8N936, DNLI4_COPC7;  Q7Z7W5, DNLI4_COPCI;
DR   P0CN09, DNLI4_CRYNB;  P0CN08, DNLI4_CRYNJ;  Q54CR9, DNLI4_DICDI;
DR   Q5BH83, DNLI4_EMENI;  P49917, DNLI4_HUMAN;  Q6CSH0, DNLI4_KLULA;
DR   Q8BTF7, DNLI4_MOUSE;  Q7SB49, DNLI4_NEUCR;  Q7X7E9, DNLI4_ORYSJ;
DR   Q0UCI9, DNLI4_PHANO;  Q5R6L3, DNLI4_PONAB;  O74833, DNLI4_SCHPO;
DR   Q6C8A3, DNLI4_YARLI;  Q08387, DNLI4_YEAST;  Q02093, DNLI_ACIAM ;
DR   Q1II25, DNLI_ACIBL ;  Q9YD18, DNLI_AERPE ;  B8JBM1, DNLI_ANAD2 ;
DR   Q2IH69, DNLI_ANADE ;  A7HID3, DNLI_ANADF ;  B4UIS1, DNLI_ANASK ;
DR   O67398, DNLI_AQUAE ;  O29632, DNLI_ARCFU ;  B8HCE1, DNLI_ARTCA ;
DR   P35970, DNLI_ASFB7 ;  P0C992, DNLI_ASFK5 ;  P26813, DNLI_ASFM2 ;
DR   P0C990, DNLI_ASFP4 ;  P0C991, DNLI_ASFWA ;  C5BW79, DNLI_BEUC1 ;
DR   P07717, DNLI_BPT3  ;  P00970, DNLI_BPT4  ;  P19088, DNLI_BPT6  ;
DR   P00969, DNLI_BPT7  ;  A8MDU6, DNLI_CALMQ ;  A0RWD6, DNLI_CENSY ;
DR   B5YD88, DNLI_DICT6 ;  B8DZX8, DNLI_DICTD ;  Q67480, DNLI_FOWPN ;
DR   P44121, DNLI_HAEIN ;  B9LUZ9, DNLI_HALLT ;  Q5V4R0, DNLI_HALMA ;
DR   B0R4C9, DNLI_HALS3 ;  Q9HR35, DNLI_HALSA ;  A2BJX6, DNLI_HYPBU ;
DR   A8AB20, DNLI_IGNH4 ;  A6WG40, DNLI_KINRD ;  A6UVC4, DNLI_META3 ;
DR   A7IAA9, DNLI_METB6 ;  Q12X08, DNLI_METBU ;  Q2FTH4, DNLI_METHJ ;
DR   Q57635, DNLI_METJA ;  Q8TWN3, DNLI_METKA ;  A2SR38, DNLI_METLZ ;
DR   A4FY19, DNLI_METM5 ;  A9AAX4, DNLI_METM6 ;  A6VFQ9, DNLI_METM7 ;
DR   A3CWP1, DNLI_METMJ ;  Q6LYM1, DNLI_METMP ;  B8GGB8, DNLI_METPE ;
DR   A5UKX2, DNLI_METS3 ;  A4YD25, DNLI_METS5 ;  Q2NHF9, DNLI_METST ;
DR   P54875, DNLI_METTF ;  Q50566, DNLI_METTH ;  A0B7F9, DNLI_METTP ;
DR   A6UNY0, DNLI_METVS ;  A0QJL0, DNLI_MYCA1 ;  Q7TTR7, DNLI_MYCBO ;
DR   A1KN60, DNLI_MYCBP ;  C1AGI1, DNLI_MYCBT ;  A4TDS2, DNLI_MYCGI ;
DR   B2HHE1, DNLI_MYCMM ;  Q73V97, DNLI_MYCPA ;  A0QUP1, DNLI_MYCS2 ;
DR   A3PXE2, DNLI_MYCSJ ;  A1UDY9, DNLI_MYCSK ;  Q1BB26, DNLI_MYCSS ;
DR   A5U776, DNLI_MYCTA ;  P95096, DNLI_MYCTU ;  A0PTC0, DNLI_MYCUA ;
DR   A1T6P2, DNLI_MYCVP ;  Q74M64, DNLI_NANEQ ;  Q3IPX0, DNLI_NATPD ;
DR   A9A3K1, DNLI_NITMS ;  Q5YNY7, DNLI_NOCFA ;  A1SKL2, DNLI_NOCSJ ;
DR   Q9YMV2, DNLI_NPVLD ;  B1ZZL9, DNLI_OPITP ;  C0QSL7, DNLI_PERMH ;
DR   Q6L195, DNLI_PICTO ;  P0CL75, DNLI_PYRAB ;  O93723, DNLI_PYRAE ;
DR   A4WH24, DNLI_PYRAR ;  P0CL74, DNLI_PYRAY ;  A3MS62, DNLI_PYRCJ ;
DR   P56709, DNLI_PYRFU ;  O59288, DNLI_PYRHO ;  A1RTK4, DNLI_PYRIL ;
DR   Q9HHC4, DNLI_PYRKO ;  C1AX87, DNLI_RHOOB ;  Q0SG75, DNLI_RHOSR ;
DR   A4F870, DNLI_SACEN ;  A9GU24, DNLI_SORC5 ;  A3DP49, DNLI_STAMF ;
DR   Q826P6, DNLI_STRAW ;  Q9FCB1, DNLI_STRCO ;  B1W5J2, DNLI_STRGG ;
DR   Q4JAM1, DNLI_SULAC ;  C3MZR1, DNLI_SULIA ;  C4KIZ2, DNLI_SULIK ;
DR   C3MJ14, DNLI_SULIL ;  C3MYD2, DNLI_SULIM ;  C3NF77, DNLI_SULIN ;
DR   C3N834, DNLI_SULIY ;  Q9P9K9, DNLI_SULSH ;  Q980T8, DNLI_SULSO ;
DR   Q976G4, DNLI_SULTO ;  Q9HJ26, DNLI_THEAC ;  Q9HH07, DNLI_THEFM ;
DR   B1YA52, DNLI_THENV ;  Q979A1, DNLI_THEVO ;  Q0W0X1, DNLI_UNCMA ;
DR   O57250, DNLI_VACCA ;  P20492, DNLI_VACCC ;  P16272, DNLI_VACCW ;
DR   P33798, DNLI_VAR67 ;  P03631, REPA_BPPHX ;  P19189, REP_BPCHP  ;
DR   P69546, REP_BPF1   ;  P69545, REP_BPFD   ;  P15419, REP_BPI22  ;
DR   O80302, REP_BPIF1  ;  P03660, REP_BPIKE  ;  P69547, REP_BPM13  ;
DR   P03627, REP_BPPF3  ;  Q38617, REP_BPPHL  ;  Q9G050, REP_BPPHM  ;
DR   P11334, REP_SPV4   ;  O34398, YKOU_BACSU ;
//
ID   6.5.1.2
DE   DNA ligase (NAD(+)).
AN   DNA joinase.
AN   DNA repair enzyme.
AN   Polydeoxyribonucleotide synthase (NAD(+)).
AN   Polydeoxyribonucleotide synthase (NAD+).
AN   Polynucleotide ligase (NAD(+)).
AN   Polynucleotide ligase (NAD+).
CA   NAD(+) + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP +
CA   nicotinamide nucleotide + (deoxyribonucleotide)(n+m).
CC   -!- Catalyzes the formation of a phosphodiester at the site of a single-
CC       strand break in duplex DNA.
CC   -!- RNA can also act as substrate, to some extent.
PR   PROSITE; PDOC00809;
DR   B8HFJ3, DNLJ1_ARTCA;  Q97JS8, DNLJ1_CLOAB;  C1D1Y6, DNLJ1_DEIDV;
DR   A1VC99, DNLJ1_DESVV;  Q5YVN7, DNLJ1_NOCFA;  B1ZWH2, DNLJ1_OPITP;
DR   Q9Z585, DNLJ1_STRCO;  B1VUC2, DNLJ1_STRGG;  B8HIQ9, DNLJ2_ARTCA;
DR   Q97FQ5, DNLJ2_CLOAB;  C1CVC7, DNLJ2_DEIDV;  A1VDM7, DNLJ2_DESVV;
DR   Q5YRS7, DNLJ2_NOCFA;  B1ZMR3, DNLJ2_OPITP;  Q93IZ8, DNLJ2_STRCO;
DR   B1VZW1, DNLJ2_STRGG;  B0C308, DNLJ_ACAM1 ;  A9NHW0, DNLJ_ACHLI ;
DR   A1TR21, DNLJ_ACIAC ;  Q6FDW0, DNLJ_ACIAD ;  B7GZ71, DNLJ_ACIB3 ;
DR   B7I790, DNLJ_ACIB5 ;  B2HUJ5, DNLJ_ACIBC ;  Q1IHJ4, DNLJ_ACIBL ;
DR   B0VU02, DNLJ_ACIBS ;  A3M2U3, DNLJ_ACIBT ;  B0V8E4, DNLJ_ACIBY ;
DR   A0LSQ7, DNLJ_ACIC1 ;  C1F7S7, DNLJ_ACIC5 ;  A5FWJ5, DNLJ_ACICJ ;
DR   B9MIW4, DNLJ_ACIET ;  B7J653, DNLJ_ACIF2 ;  B5EP61, DNLJ_ACIF5 ;
DR   A1W7N4, DNLJ_ACISJ ;  A3N1V2, DNLJ_ACTP2 ;  B3H275, DNLJ_ACTP7 ;
DR   B0BQN6, DNLJ_ACTPJ ;  A6VR16, DNLJ_ACTSZ ;  A0KHL9, DNLJ_AERHH ;
DR   A4SKA6, DNLJ_AERS4 ;  B9JH39, DNLJ_AGRRK ;  A9CIB3, DNLJ_AGRT5 ;
DR   B9JY41, DNLJ_AGRVS ;  B2UL69, DNLJ_AKKM8 ;  Q0VR01, DNLJ_ALCBS ;
DR   Q0AAV2, DNLJ_ALHEH ;  B6EJQ6, DNLJ_ALISL ;  A6TLU4, DNLJ_ALKMQ ;
DR   A8MLJ8, DNLJ_ALKOO ;  C3L496, DNLJ_AMOA5 ;  B8JD56, DNLJ_ANAD2 ;
DR   Q2INT9, DNLJ_ANADE ;  A7H8A2, DNLJ_ANADF ;  B9KHN8, DNLJ_ANAMF ;
DR   Q5PBN8, DNLJ_ANAMM ;  Q2GLI8, DNLJ_ANAPZ ;  B4UDH6, DNLJ_ANASK ;
DR   B9MK54, DNLJ_ANATD ;  Q3MGE7, DNLJ_ANAVT ;  B7GFV1, DNLJ_ANOFW ;
DR   O66880, DNLJ_AQUAE ;  A8ETQ3, DNLJ_ARCB4 ;  Q5NYU3, DNLJ_AROAE ;
DR   A1R4P6, DNLJ_ARTAT ;  A0JUH2, DNLJ_ARTS2 ;  Q2NJF5, DNLJ_AYWBP ;
DR   A8IGY0, DNLJ_AZOC5 ;  B6YRR9, DNLJ_AZOPC ;  A1K713, DNLJ_AZOSB ;
DR   C1DN27, DNLJ_AZOVD ;  A7Z261, DNLJ_BACA2 ;  C3PBP1, DNLJ_BACAA ;
DR   C3L543, DNLJ_BACAC ;  A0R906, DNLJ_BACAH ;  Q81ZG1, DNLJ_BACAN ;
DR   B7JM96, DNLJ_BACC0 ;  Q73EM3, DNLJ_BACC1 ;  B7IUW5, DNLJ_BACC2 ;
DR   C1EV74, DNLJ_BACC3 ;  B7H4U8, DNLJ_BACC4 ;  B7HSW5, DNLJ_BACC7 ;
DR   A7GKJ1, DNLJ_BACCN ;  B9J1L6, DNLJ_BACCQ ;  Q81IP2, DNLJ_BACCR ;
DR   Q63GS3, DNLJ_BACCZ ;  Q5LCI0, DNLJ_BACFN ;  Q64TM7, DNLJ_BACFR ;
DR   Q9KF37, DNLJ_BACHD ;  Q6HP94, DNLJ_BACHK ;  Q65MR2, DNLJ_BACLD ;
DR   A8FAQ1, DNLJ_BACP2 ;  Q5WJ30, DNLJ_BACSK ;  O31498, DNLJ_BACSU ;
DR   Q8A9C1, DNLJ_BACTN ;  A6L5G8, DNLJ_BACV8 ;  A9VRG3, DNLJ_BACWK ;
DR   A1UTB5, DNLJ_BARBK ;  Q6G2R5, DNLJ_BARHE ;  Q6FZ81, DNLJ_BARQU ;
DR   A9IW95, DNLJ_BART1 ;  Q1LU20, DNLJ_BAUCH ;  Q6MRL9, DNLJ_BDEBA ;
DR   B2IGH4, DNLJ_BEII9 ;  B8DU32, DNLJ_BIFA0 ;  A1A200, DNLJ_BIFAA ;
DR   B3DPR8, DNLJ_BIFLD ;  Q8G830, DNLJ_BIFLO ;  B7GPV4, DNLJ_BIFLS ;
DR   Q7VRU2, DNLJ_BLOFL ;  Q492G5, DNLJ_BLOPB ;  Q2KUU5, DNLJ_BORA1 ;
DR   Q0SMV7, DNLJ_BORAP ;  Q7WCJ7, DNLJ_BORBR ;  O51502, DNLJ_BORBU ;
DR   B7J2B3, DNLJ_BORBZ ;  B5RMA6, DNLJ_BORDL ;  Q660X2, DNLJ_BORGA ;
DR   B2S0Q2, DNLJ_BORHD ;  Q7W0T4, DNLJ_BORPA ;  A9II69, DNLJ_BORPD ;
DR   Q7VRX7, DNLJ_BORPE ;  B5RPQ2, DNLJ_BORRA ;  A1QZY4, DNLJ_BORT9 ;
DR   C0QVE5, DNLJ_BRAHW ;  Q89FV8, DNLJ_BRAJA ;  A5EPJ2, DNLJ_BRASB ;
DR   A4YZJ3, DNLJ_BRASO ;  C0Z4D6, DNLJ_BREBN ;  B2S6P4, DNLJ_BRUA1 ;
DR   Q2YLZ6, DNLJ_BRUA2 ;  Q57C89, DNLJ_BRUAB ;  A9M679, DNLJ_BRUC2 ;
DR   C0RE59, DNLJ_BRUMB ;  Q8YI56, DNLJ_BRUME ;  A5VRG5, DNLJ_BRUO2 ;
DR   B0CHK8, DNLJ_BRUSI ;  Q8FZQ3, DNLJ_BRUSU ;  B8D8M5, DNLJ_BUCA5 ;
DR   P57172, DNLJ_BUCAI ;  B8D6X9, DNLJ_BUCAT ;  Q89B02, DNLJ_BUCBP ;
DR   Q058C9, DNLJ_BUCCC ;  B1YSH2, DNLJ_BURA4 ;  Q1BHI7, DNLJ_BURCA ;
DR   B1JUF5, DNLJ_BURCC ;  A0K8E8, DNLJ_BURCH ;  B4ECN6, DNLJ_BURCJ ;
DR   Q0BE10, DNLJ_BURCM ;  A9AIK9, DNLJ_BURM1 ;  A3MKU9, DNLJ_BURM7 ;
DR   A2SB66, DNLJ_BURM9 ;  Q62JB9, DNLJ_BURMA ;  A1V575, DNLJ_BURMS ;
DR   A3NWN7, DNLJ_BURP0 ;  Q3JR23, DNLJ_BURP1 ;  A3NAV3, DNLJ_BURP6 ;
DR   B2JID1, DNLJ_BURP8 ;  B2T5K0, DNLJ_BURPP ;  Q63T07, DNLJ_BURPS ;
DR   Q39F38, DNLJ_BURS3 ;  Q2SX03, DNLJ_BURTA ;  A4JF81, DNLJ_BURVG ;
DR   Q13XB0, DNLJ_BURXL ;  A4XK85, DNLJ_CALS8 ;  A7ZED8, DNLJ_CAMC1 ;
DR   A7GXS4, DNLJ_CAMC5 ;  A0RPY7, DNLJ_CAMFF ;  A7I236, DNLJ_CAMHC ;
DR   A8FL10, DNLJ_CAMJ8 ;  A7H3U4, DNLJ_CAMJD ;  Q0PAT1, DNLJ_CAMJE ;
DR   A1VYU6, DNLJ_CAMJJ ;  Q5HVI4, DNLJ_CAMJR ;  B9KG17, DNLJ_CAMLR ;
DR   Q3AD38, DNLJ_CARHZ ;  B8H5Y7, DNLJ_CAUCN ;  Q9A842, DNLJ_CAUCR ;
DR   B0T1N5, DNLJ_CAUSK ;  B3PGQ8, DNLJ_CELJU ;  A9WCA1, DNLJ_CHLAA ;
DR   Q5L5Q2, DNLJ_CHLAB ;  B8GAC1, DNLJ_CHLAD ;  Q3ATX4, DNLJ_CHLCH ;
DR   Q822R2, DNLJ_CHLCV ;  Q254X9, DNLJ_CHLFF ;  B3EFT6, DNLJ_CHLL2 ;
DR   Q9PKP2, DNLJ_CHLMU ;  B3QLI5, DNLJ_CHLP8 ;  B3EM49, DNLJ_CHLPB ;
DR   A1BDQ5, DNLJ_CHLPD ;  Q9Z934, DNLJ_CHLPN ;  B9LHI6, DNLJ_CHLSY ;
DR   B0B9Q4, DNLJ_CHLT2 ;  B3QSH0, DNLJ_CHLT3 ;  Q3KMM3, DNLJ_CHLTA ;
DR   B0BBD3, DNLJ_CHLTB ;  Q8KF74, DNLJ_CHLTE ;  O84148, DNLJ_CHLTR ;
DR   Q1QZP4, DNLJ_CHRSD ;  Q7NR81, DNLJ_CHRVO ;  A8ADI2, DNLJ_CITK8 ;
DR   A5CQU5, DNLJ_CLAM3 ;  B0RGA7, DNLJ_CLAMS ;  A7FYL7, DNLJ_CLOB1 ;
DR   C3KUA1, DNLJ_CLOB6 ;  A6LQB0, DNLJ_CLOB8 ;  B2UZ23, DNLJ_CLOBA ;
DR   B2TIZ7, DNLJ_CLOBB ;  A5I6Z7, DNLJ_CLOBH ;  C1FLS8, DNLJ_CLOBJ ;
DR   B1ING1, DNLJ_CLOBK ;  A7GIK6, DNLJ_CLOBL ;  B1L1H3, DNLJ_CLOBM ;
DR   B8I3I1, DNLJ_CLOCE ;  Q180F3, DNLJ_CLOD6 ;  B9DWM9, DNLJ_CLOK1 ;
DR   A5N2X7, DNLJ_CLOK5 ;  A0Q2Q3, DNLJ_CLONN ;  Q0TN59, DNLJ_CLOP1 ;
DR   Q8XI62, DNLJ_CLOPE ;  A9KPL0, DNLJ_CLOPH ;  Q0SQT6, DNLJ_CLOPS ;
DR   Q891I0, DNLJ_CLOTE ;  A3DE88, DNLJ_CLOTH ;  Q47YI0, DNLJ_COLP3 ;
DR   B5Y6V5, DNLJ_COPPD ;  C3PFU5, DNLJ_CORA7 ;  Q6NHQ4, DNLJ_CORDI ;
DR   Q8FPZ7, DNLJ_COREF ;  A4QDK5, DNLJ_CORGB ;  Q8NR20, DNLJ_CORGL ;
DR   Q4JUL8, DNLJ_CORJK ;  B1VG01, DNLJ_CORU7 ;  B6J878, DNLJ_COXB1 ;
DR   B6J1C6, DNLJ_COXB2 ;  A9KCS0, DNLJ_COXBN ;  A9NC33, DNLJ_COXBR ;
DR   Q83DZ6, DNLJ_COXBU ;  Q0KA11, DNLJ_CUPNH ;  Q470D2, DNLJ_CUPPJ ;
DR   B3R2C2, DNLJ_CUPTR ;  B1WZL6, DNLJ_CYAA5 ;  B8HV17, DNLJ_CYAP4 ;
DR   B7K8U0, DNLJ_CYAP7 ;  B7K0A2, DNLJ_CYAP8 ;  Q11VI1, DNLJ_CYTH3 ;
DR   Q47FA0, DNLJ_DECAR ;  Q3Z8W1, DNLJ_DEHE1 ;  A5FRL4, DNLJ_DEHSB ;
DR   Q3ZX08, DNLJ_DEHSC ;  Q1J0I6, DNLJ_DEIGD ;  Q9RSQ5, DNLJ_DEIRA ;
DR   A9BZW4, DNLJ_DELAS ;  B8FKD5, DNLJ_DESAA ;  C0QJ86, DNLJ_DESAH ;
DR   B1I551, DNLJ_DESAP ;  B8J0Q0, DNLJ_DESDA ;  Q30ZK6, DNLJ_DESDG ;
DR   B8FP44, DNLJ_DESHD ;  Q24QL5, DNLJ_DESHY ;  A9A0L9, DNLJ_DESOH ;
DR   Q6API9, DNLJ_DESPS ;  A4J703, DNLJ_DESRM ;  Q72BM7, DNLJ_DESVH ;
DR   B8DJT6, DNLJ_DESVM ;  A5EVZ5, DNLJ_DICNV ;  A8LK52, DNLJ_DINSH ;
DR   A7ZPL2, DNLJ_ECO24 ;  B7UGB2, DNLJ_ECO27 ;  B7MHR5, DNLJ_ECO45 ;
DR   B7LCF6, DNLJ_ECO55 ;  Q8XBL5, DNLJ_ECO57 ;  B5YZV8, DNLJ_ECO5E ;
DR   B7NPU7, DNLJ_ECO7I ;  B7MY64, DNLJ_ECO81 ;  B7M6S1, DNLJ_ECO8A ;
DR   B1XA82, DNLJ_ECODH ;  A8A2Q7, DNLJ_ECOHS ;  A1ADS8, DNLJ_ECOK1 ;
DR   Q0TF55, DNLJ_ECOL5 ;  Q8FFC1, DNLJ_ECOL6 ;  B1IX60, DNLJ_ECOLC ;
DR   P15042, DNLJ_ECOLI ;  B7N602, DNLJ_ECOLU ;  B6I4Y8, DNLJ_ECOSE ;
DR   B1LMK5, DNLJ_ECOSM ;  Q1R8W1, DNLJ_ECOUT ;  Q3YRC1, DNLJ_EHRCJ ;
DR   Q2GHG1, DNLJ_EHRCR ;  Q5FG20, DNLJ_EHRRG ;  Q5HAI7, DNLJ_EHRRW ;
DR   B2KE31, DNLJ_ELUMP ;  A4WD23, DNLJ_ENT38 ;  Q837V6, DNLJ_ENTFA ;
DR   A7MKW4, DNLJ_ENTS8 ;  Q6D165, DNLJ_ERWCT ;  B2VE40, DNLJ_ERWT9 ;
DR   Q2N9V6, DNLJ_ERYLH ;  B7LL73, DNLJ_ESCF3 ;  B1YJ17, DNLJ_EXIS2 ;
DR   A7HJG6, DNLJ_FERNB ;  B0RZW0, DNLJ_FINM2 ;  A5FE87, DNLJ_FLAJ1 ;
DR   A6H0N9, DNLJ_FLAPJ ;  Q0RDH8, DNLJ_FRAAA ;  B0TY02, DNLJ_FRAP2 ;
DR   Q2J6U3, DNLJ_FRASC ;  A8L538, DNLJ_FRASN ;  Q14GL3, DNLJ_FRAT1 ;
DR   A7NB34, DNLJ_FRATF ;  Q2A4C4, DNLJ_FRATH ;  B2SFT1, DNLJ_FRATM ;
DR   A0Q7L0, DNLJ_FRATN ;  Q0BMQ3, DNLJ_FRATO ;  Q5NF60, DNLJ_FRATT ;
DR   A4IWW8, DNLJ_FRATW ;  Q8RI94, DNLJ_FUSNN ;  C1A6H2, DNLJ_GEMAT ;
DR   B5EIJ0, DNLJ_GEOBB ;  Q5L3B9, DNLJ_GEOKA ;  B3E8F8, DNLJ_GEOLS ;
DR   Q39S28, DNLJ_GEOMG ;  O87703, DNLJ_GEOSE ;  B9M861, DNLJ_GEOSF ;
DR   Q74ER9, DNLJ_GEOSL ;  A4IJY6, DNLJ_GEOTN ;  A5GA98, DNLJ_GEOUR ;
DR   Q7NMN8, DNLJ_GLOVI ;  A9H0L6, DNLJ_GLUDA ;  Q5FUI5, DNLJ_GLUOX ;
DR   Q0BV35, DNLJ_GRABC ;  A0LZ23, DNLJ_GRAFK ;  Q7VMX7, DNLJ_HAEDU ;
DR   Q4QLJ0, DNLJ_HAEI8 ;  A5UD04, DNLJ_HAEIE ;  A5UIM6, DNLJ_HAEIG ;
DR   P43813, DNLJ_HAEIN ;  B8F314, DNLJ_HAEPS ;  Q0I2H6, DNLJ_HAES1 ;
DR   B0USD9, DNLJ_HAES2 ;  Q2SD47, DNLJ_HAHCH ;  A1WY80, DNLJ_HALHL ;
DR   B9LU22, DNLJ_HALLT ;  Q5UY84, DNLJ_HALMA ;  B8D122, DNLJ_HALOH ;
DR   Q18E49, DNLJ_HALWD ;  C4K4K4, DNLJ_HAMD5 ;  Q17XL1, DNLJ_HELAH ;
DR   Q7VF74, DNLJ_HELHP ;  B0TDL0, DNLJ_HELMI ;  B6JLJ9, DNLJ_HELP2 ;
DR   B5Z6Y6, DNLJ_HELPG ;  Q1CTQ9, DNLJ_HELPH ;  Q9ZLM1, DNLJ_HELPJ ;
DR   B2UTL2, DNLJ_HELPS ;  O25336, DNLJ_HELPY ;  A9AXP4, DNLJ_HERA2 ;
DR   A4G4R4, DNLJ_HERAR ;  B4U8X0, DNLJ_HYDS0 ;  Q0C577, DNLJ_HYPNA ;
DR   Q5QUK1, DNLJ_IDILO ;  A6SZQ8, DNLJ_JANMA ;  Q28PE1, DNLJ_JANSC ;
DR   A6W7L4, DNLJ_KINRD ;  B5XVT4, DNLJ_KLEP3 ;  A6TC47, DNLJ_KLEP7 ;
DR   B2GL64, DNLJ_KOCRD ;  Q5FLL4, DNLJ_LACAC ;  Q03Q13, DNLJ_LACBA ;
DR   Q03AC3, DNLJ_LACC3 ;  B3WD54, DNLJ_LACCB ;  Q1GBF7, DNLJ_LACDA ;
DR   Q04BW0, DNLJ_LACDB ;  B2GDS9, DNLJ_LACF3 ;  Q041K2, DNLJ_LACGA ;
DR   A8YTZ3, DNLJ_LACH4 ;  Q74I49, DNLJ_LACJO ;  Q9CIE4, DNLJ_LACLA ;
DR   A2RIF3, DNLJ_LACLM ;  Q031P9, DNLJ_LACLS ;  Q88XQ0, DNLJ_LACPL ;
DR   A5VLG6, DNLJ_LACRD ;  B2G8T9, DNLJ_LACRJ ;  Q1WSH6, DNLJ_LACS1 ;
DR   Q38VC5, DNLJ_LACSS ;  C1D4R5, DNLJ_LARHH ;  Q1MRS8, DNLJ_LAWIP ;
DR   Q5X6E6, DNLJ_LEGPA ;  A5IFV1, DNLJ_LEGPC ;  Q5ZWX6, DNLJ_LEGPH ;
DR   Q5WXV3, DNLJ_LEGPL ;  Q6AEE5, DNLJ_LEIXX ;  B0SA75, DNLJ_LEPBA ;
DR   Q04W02, DNLJ_LEPBJ ;  Q04XH0, DNLJ_LEPBL ;  B0SKC1, DNLJ_LEPBP ;
DR   B1Y6D4, DNLJ_LEPCP ;  Q72MA6, DNLJ_LEPIC ;  Q8EYU4, DNLJ_LEPIN ;
DR   B1MXQ8, DNLJ_LEUCK ;  Q03YP0, DNLJ_LEUMM ;  Q92AQ0, DNLJ_LISIN ;
DR   C1KW57, DNLJ_LISMC ;  Q71YR0, DNLJ_LISMF ;  B8DFG5, DNLJ_LISMH ;
DR   Q8Y6D0, DNLJ_LISMO ;  A0AJL1, DNLJ_LISW6 ;  B1HTW6, DNLJ_LYSSC ;
DR   B9E830, DNLJ_MACCJ ;  Q2W0G3, DNLJ_MAGSA ;  A0LDY1, DNLJ_MAGSM ;
DR   Q65RN7, DNLJ_MANSM ;  A1TZT9, DNLJ_MARAV ;  Q0AMX9, DNLJ_MARMM ;
DR   A6W0S9, DNLJ_MARMS ;  Q6F1V7, DNLJ_MESFL ;  Q11GT5, DNLJ_MESSB ;
DR   B7KU78, DNLJ_METC4 ;  Q604U8, DNLJ_METCA ;  A9VWA4, DNLJ_METEP ;
DR   Q1H1G6, DNLJ_METFK ;  B3DWU2, DNLJ_METI4 ;  B8ICE5, DNLJ_METNO ;
DR   B1Z9P1, DNLJ_METPB ;  A2SGT2, DNLJ_METPP ;  B1M575, DNLJ_METRJ ;
DR   B0UQ51, DNLJ_METS4 ;  B8ETN6, DNLJ_METSB ;  B0JTW2, DNLJ_MICAN ;
DR   Q5UPZ0, DNLJ_MIMIV ;  Q2RGY0, DNLJ_MOOTA ;  A0QJE3, DNLJ_MYCA1 ;
DR   B3PMJ0, DNLJ_MYCA5 ;  B1MDV2, DNLJ_MYCA9 ;  A5IY71, DNLJ_MYCAP ;
DR   P63974, DNLJ_MYCBO ;  A1KN09, DNLJ_MYCBP ;  C1AGD0, DNLJ_MYCBT ;
DR   Q2SRE1, DNLJ_MYCCT ;  Q7NAF8, DNLJ_MYCGA ;  P47496, DNLJ_MYCGE ;
DR   A4TDZ8, DNLJ_MYCGI ;  Q601T8, DNLJ_MYCH2 ;  Q4A899, DNLJ_MYCH7 ;
DR   Q4AA72, DNLJ_MYCHJ ;  B8ZS27, DNLJ_MYCLB ;  O33102, DNLJ_MYCLE ;
DR   B2HIF0, DNLJ_MYCMM ;  Q6KI95, DNLJ_MYCMO ;  Q6MSK8, DNLJ_MYCMS ;
DR   Q8EWL9, DNLJ_MYCPE ;  P78021, DNLJ_MYCPN ;  Q98QH2, DNLJ_MYCPU ;
DR   A0QUW7, DNLJ_MYCS2 ;  Q4A5J6, DNLJ_MYCS5 ;  A3PXM2, DNLJ_MYCSJ ;
DR   A1UE68, DNLJ_MYCSK ;  Q1BAU4, DNLJ_MYCSS ;  A5U726, DNLJ_MYCTA ;
DR   P63973, DNLJ_MYCTU ;  A0PPW9, DNLJ_MYCUA ;  A1T6X7, DNLJ_MYCVP ;
DR   Q1D0P7, DNLJ_MYXXD ;  Q3ITK1, DNLJ_NATPD ;  B2A5W5, DNLJ_NATTJ ;
DR   B9L8R4, DNLJ_NAUPA ;  Q5F9Z9, DNLJ_NEIG1 ;  B4RJQ9, DNLJ_NEIG2 ;
DR   A9M2U7, DNLJ_NEIM0 ;  A1IQR7, DNLJ_NEIMA ;  Q9K0E3, DNLJ_NEIMB ;
DR   A1KSS7, DNLJ_NEIMF ;  Q2GDR2, DNLJ_NEOSM ;  Q0AHH6, DNLJ_NITEC ;
DR   Q82TW6, DNLJ_NITEU ;  Q1QNT2, DNLJ_NITHX ;  Q2YBB7, DNLJ_NITMU ;
DR   Q3JAI1, DNLJ_NITOC ;  A6Q433, DNLJ_NITSB ;  Q3STR7, DNLJ_NITWN ;
DR   A1SMA5, DNLJ_NOCSJ ;  B2J3P0, DNLJ_NOSP7 ;  Q8YW98, DNLJ_NOSS1 ;
DR   Q2G7J5, DNLJ_NOVAD ;  Q8CXK6, DNLJ_OCEIH ;  A6WZR6, DNLJ_OCHA4 ;
DR   Q04GN6, DNLJ_OENOB ;  B6JB45, DNLJ_OLICO ;  Q6YQD6, DNLJ_ONYPE ;
DR   A5CEY0, DNLJ_ORITB ;  B3CVK1, DNLJ_ORITI ;  A6LA55, DNLJ_PARD8 ;
DR   A1B9F5, DNLJ_PARDP ;  A7HVV8, DNLJ_PARL1 ;  Q6MAB5, DNLJ_PARUW ;
DR   Q9CKA9, DNLJ_PASMU ;  Q03DT9, DNLJ_PEDPA ;  Q3A2F5, DNLJ_PELCD ;
DR   Q3B278, DNLJ_PELLD ;  B4SCX5, DNLJ_PELPB ;  A1ATJ6, DNLJ_PELPD ;
DR   A5CZ68, DNLJ_PELTS ;  Q4FPL3, DNLJ_PELUB ;  C0QSF6, DNLJ_PERMH ;
DR   A9BJX5, DNLJ_PETMO ;  B4RFE9, DNLJ_PHEZH ;  Q7MBH2, DNLJ_PHOLL ;
DR   Q6LTU5, DNLJ_PHOPR ;  B1VAY1, DNLJ_PHYAS ;  B3QZS5, DNLJ_PHYMT ;
DR   A1VN98, DNLJ_POLNA ;  B1XTU0, DNLJ_POLNS ;  Q12AD4, DNLJ_POLSJ ;
DR   A4SYV5, DNLJ_POLSQ ;  B2RKL2, DNLJ_PORG3 ;  Q7MV47, DNLJ_PORGI ;
DR   B4S4Y6, DNLJ_PROA2 ;  Q6A7A2, DNLJ_PROAC ;  A2C5E6, DNLJ_PROM1 ;
DR   A2CDS6, DNLJ_PROM3 ;  A9BDC5, DNLJ_PROM4 ;  Q7V9J2, DNLJ_PROMA ;
DR   B4EZR2, DNLJ_PROMH ;  Q7V3Z9, DNLJ_PROMM ;  Q46IA9, DNLJ_PROMT ;
DR   A4SG85, DNLJ_PROVI ;  Q48KR2, DNLJ_PSE14 ;  Q15UZ1, DNLJ_PSEA6 ;
DR   A6V7X3, DNLJ_PSEA7 ;  B7UVJ3, DNLJ_PSEA8 ;  Q02K12, DNLJ_PSEAB ;
DR   Q9I3I4, DNLJ_PSEAE ;  Q1ICK0, DNLJ_PSEE4 ;  Q4KFH1, DNLJ_PSEF5 ;
DR   C3JXX6, DNLJ_PSEFS ;  Q3IKB8, DNLJ_PSEHT ;  A4XVY5, DNLJ_PSEMY ;
DR   A5W0U0, DNLJ_PSEP1 ;  Q3KFB2, DNLJ_PSEPF ;  B0KPX3, DNLJ_PSEPG ;
DR   Q88F25, DNLJ_PSEPK ;  B1JC06, DNLJ_PSEPW ;  Q87YY6, DNLJ_PSESM ;
DR   Q4ZVF6, DNLJ_PSEU2 ;  A4VKN0, DNLJ_PSEU5 ;  Q4FUW9, DNLJ_PSYA2 ;
DR   Q1QDW8, DNLJ_PSYCK ;  A1SX61, DNLJ_PSYIN ;  A5WCN7, DNLJ_PSYWF ;
DR   Q1LNG5, DNLJ_RALME ;  B2UB00, DNLJ_RALPJ ;  Q8XZJ7, DNLJ_RALSO ;
DR   A9WTZ3, DNLJ_RENSM ;  B3PTU7, DNLJ_RHIE6 ;  Q2K6D3, DNLJ_RHIEC ;
DR   Q1ME47, DNLJ_RHIL3 ;  Q98KC4, DNLJ_RHILO ;  B5ZWH9, DNLJ_RHILW ;
DR   Q92NM8, DNLJ_RHIME ;  C3MEL9, DNLJ_RHISN ;  Q7UKD1, DNLJ_RHOBA ;
DR   B6IRF1, DNLJ_RHOCS ;  C0ZXK3, DNLJ_RHOE4 ;  Q21WC8, DNLJ_RHOFD ;
DR   P49421, DNLJ_RHOMR ;  C1B1S4, DNLJ_RHOOB ;  Q2IYJ4, DNLJ_RHOP2 ;
DR   Q07PR9, DNLJ_RHOP5 ;  Q6N423, DNLJ_RHOPA ;  Q211V0, DNLJ_RHOPB ;
DR   Q133Y4, DNLJ_RHOPS ;  B3QFL8, DNLJ_RHOPT ;  Q2RVV5, DNLJ_RHORT ;
DR   A3PJ74, DNLJ_RHOS1 ;  Q3J355, DNLJ_RHOS4 ;  A4WRP6, DNLJ_RHOS5 ;
DR   B9KRK2, DNLJ_RHOSK ;  Q0S2J2, DNLJ_RHOSR ;  C3PLJ2, DNLJ_RICAE ;
DR   A8GPM9, DNLJ_RICAH ;  A8GXT8, DNLJ_RICB8 ;  Q1RK40, DNLJ_RICBR ;
DR   A8EZT5, DNLJ_RICCK ;  Q92GM7, DNLJ_RICCN ;  Q4UN15, DNLJ_RICFE ;
DR   A8F2K5, DNLJ_RICM5 ;  Q9ZCK9, DNLJ_RICPR ;  C4K0T1, DNLJ_RICPU ;
DR   B0BUZ1, DNLJ_RICRO ;  A8GTF2, DNLJ_RICRS ;  Q68W27, DNLJ_RICTY ;
DR   A7NHP6, DNLJ_ROSCS ;  Q166E0, DNLJ_ROSDO ;  A5V1U3, DNLJ_ROSS1 ;
DR   Q1AZ75, DNLJ_RUBXD ;  A1AVV5, DNLJ_RUTMC ;  Q21JI8, DNLJ_SACD2 ;
DR   A4FMS5, DNLJ_SACEN ;  B5F0F5, DNLJ_SALA4 ;  A8M5E3, DNLJ_SALAI ;
DR   A9MIG0, DNLJ_SALAR ;  Q57LT1, DNLJ_SALCH ;  B5FQB9, DNLJ_SALDC ;
DR   B5R3V4, DNLJ_SALEP ;  B5RCP9, DNLJ_SALG2 ;  B4TCF6, DNLJ_SALHS ;
DR   B4SZU5, DNLJ_SALNS ;  Q5PNE2, DNLJ_SALPA ;  A9N362, DNLJ_SALPB ;
DR   C0PZB4, DNLJ_SALPC ;  B5BB72, DNLJ_SALPK ;  Q2S459, DNLJ_SALRD ;
DR   B4TQF8, DNLJ_SALSV ;  Q8Z4W4, DNLJ_SALTI ;  A4X487, DNLJ_SALTO ;
DR   Q8ZN89, DNLJ_SALTY ;  A8GHF2, DNLJ_SERP5 ;  A1S5R7, DNLJ_SHEAM ;
DR   B8EEK5, DNLJ_SHEB2 ;  A3D5Y2, DNLJ_SHEB5 ;  A6WPS5, DNLJ_SHEB8 ;
DR   A9L5Z1, DNLJ_SHEB9 ;  Q12L82, DNLJ_SHEDO ;  Q080K9, DNLJ_SHEFN ;
DR   B0TKB2, DNLJ_SHEHH ;  A3QFJ5, DNLJ_SHELP ;  Q8ED70, DNLJ_SHEON ;
DR   A8H376, DNLJ_SHEPA ;  A4Y802, DNLJ_SHEPC ;  B8CN91, DNLJ_SHEPW ;
DR   A0KVI4, DNLJ_SHESA ;  A8FU26, DNLJ_SHESH ;  Q0HK31, DNLJ_SHESM ;
DR   Q0HWD2, DNLJ_SHESR ;  A1RII7, DNLJ_SHESW ;  B1KJT5, DNLJ_SHEWM ;
DR   Q31Y68, DNLJ_SHIBS ;  Q32DE2, DNLJ_SHIDS ;  Q0T298, DNLJ_SHIF8 ;
DR   Q83K81, DNLJ_SHIFL ;  Q3YZD1, DNLJ_SHISS ;  Q5LST6, DNLJ_SILPO ;
DR   Q1GGT5, DNLJ_SILST ;  A6UB73, DNLJ_SINMW ;  Q2NSC2, DNLJ_SODGM ;
DR   Q01NV7, DNLJ_SOLUE ;  A9F3W3, DNLJ_SORC5 ;  Q1GVQ2, DNLJ_SPHAL ;
DR   A5VFJ8, DNLJ_SPHWW ;  Q14L37, DNLJ_SPICI ;  A7X432, DNLJ_STAA1 ;
DR   A6U309, DNLJ_STAA2 ;  Q2FFJ1, DNLJ_STAA3 ;  Q2G1Y0, DNLJ_STAA8 ;
DR   A5IU71, DNLJ_STAA9 ;  Q2YU70, DNLJ_STAAB ;  Q5HEL8, DNLJ_STAAC ;
DR   A6QID2, DNLJ_STAAE ;  Q99SY3, DNLJ_STAAM ;  Q7A4Q5, DNLJ_STAAN ;
DR   Q6GFF3, DNLJ_STAAR ;  Q6G829, DNLJ_STAAS ;  A8Z2R8, DNLJ_STAAT ;
DR   Q9AIU7, DNLJ_STAAU ;  Q7A0H1, DNLJ_STAAW ;  B9DMU3, DNLJ_STACT ;
DR   Q5HN30, DNLJ_STAEQ ;  Q8CRU0, DNLJ_STAES ;  Q4L7L9, DNLJ_STAHJ ;
DR   Q49YU8, DNLJ_STAS1 ;  Q3K1K8, DNLJ_STRA1 ;  Q8E5W1, DNLJ_STRA3 ;
DR   Q8E084, DNLJ_STRA5 ;  Q82JK7, DNLJ_STRAW ;  C0M6L2, DNLJ_STRE4 ;
DR   B4U2C7, DNLJ_STREM ;  A8AY10, DNLJ_STRGC ;  B4SP88, DNLJ_STRM5 ;
DR   B2FKJ1, DNLJ_STRMK ;  Q8DT49, DNLJ_STRMU ;  Q9A0J5, DNLJ_STRP1 ;
DR   Q04KH2, DNLJ_STRP2 ;  P0DA72, DNLJ_STRP3 ;  B5E4M9, DNLJ_STRP4 ;
DR   Q5XCY8, DNLJ_STRP6 ;  C1C7B1, DNLJ_STRP7 ;  Q8P1L1, DNLJ_STRP8 ;
DR   Q1JCM1, DNLJ_STRPB ;  Q1JMJ7, DNLJ_STRPC ;  Q1JHP3, DNLJ_STRPD ;
DR   Q1J7G9, DNLJ_STRPF ;  A2RFD0, DNLJ_STRPG ;  B1IBQ3, DNLJ_STRPI ;
DR   B8ZPV9, DNLJ_STRPJ ;  Q48UE1, DNLJ_STRPM ;  Q97QT2, DNLJ_STRPN ;
DR   P0DA73, DNLJ_STRPQ ;  B2IPZ1, DNLJ_STRPS ;  B5XKP3, DNLJ_STRPZ ;
DR   Q8DPS9, DNLJ_STRR6 ;  A4W1W6, DNLJ_STRS2 ;  A3CNX3, DNLJ_STRSV ;
DR   A4VVK7, DNLJ_STRSY ;  Q5LYL9, DNLJ_STRT1 ;  Q5M382, DNLJ_STRT2 ;
DR   Q03JF6, DNLJ_STRTD ;  B9DRS2, DNLJ_STRU0 ;  C1CEA4, DNLJ_STRZJ ;
DR   C1CKI0, DNLJ_STRZP ;  C1CRL7, DNLJ_STRZT ;  C1DW63, DNLJ_SULAA ;
DR   Q30QV9, DNLJ_SULDN ;  A6Q7G2, DNLJ_SULNB ;  B2V5U1, DNLJ_SULSY ;
DR   Q67KI8, DNLJ_SYMTH ;  Q2LTN8, DNLJ_SYNAS ;  Q31RL0, DNLJ_SYNE7 ;
DR   A0LI67, DNLJ_SYNFM ;  Q2JW63, DNLJ_SYNJA ;  Q2JLU3, DNLJ_SYNJB ;
DR   B1XLV0, DNLJ_SYNP2 ;  Q5N2P4, DNLJ_SYNP6 ;  A5GPI9, DNLJ_SYNPW ;
DR   Q7U3P1, DNLJ_SYNPX ;  A5GWQ3, DNLJ_SYNR3 ;  Q0I6C8, DNLJ_SYNS3 ;
DR   Q3AUH7, DNLJ_SYNS9 ;  Q3AGK2, DNLJ_SYNSC ;  Q0AZZ5, DNLJ_SYNWW ;
DR   P72588, DNLJ_SYNY3 ;  B7IDX6, DNLJ_THEAB ;  Q8DKK2, DNLJ_THEEB ;
DR   Q9ZHI0, DNLJ_THEFI ;  Q47SC6, DNLJ_THEFY ;  A8F541, DNLJ_THELT ;
DR   A6LN55, DNLJ_THEM4 ;  Q9WXV5, DNLJ_THEMA ;  B9K734, DNLJ_THENN ;
DR   A5IKX0, DNLJ_THEP1 ;  B0KBN6, DNLJ_THEP3 ;  B0K3S1, DNLJ_THEPX ;
DR   B9KXM2, DNLJ_THERP ;  P49422, DNLJ_THESC ;  Q9ZFY8, DNLJ_THESK ;
DR   B1LA51, DNLJ_THESQ ;  Q72JN8, DNLJ_THET2 ;  P26996, DNLJ_THET8 ;
DR   Q8RC42, DNLJ_THETN ;  B5YIF8, DNLJ_THEYD ;  Q31G89, DNLJ_THICR ;
DR   Q3SL40, DNLJ_THIDA ;  B8GTL0, DNLJ_THISH ;  Q73MH0, DNLJ_TREDE ;
DR   O83642, DNLJ_TREPA ;  B2S3M4, DNLJ_TREPS ;  Q112N5, DNLJ_TRIEI ;
DR   Q83HX4, DNLJ_TROW8 ;  Q83G99, DNLJ_TROWT ;  B1H072, DNLJ_UNCTG ;
DR   B1AIB0, DNLJ_UREP2 ;  Q9PR23, DNLJ_UREPA ;  B5ZAV3, DNLJ_UREU1 ;
DR   A1WRA7, DNLJ_VEREI ;  A5CXB8, DNLJ_VESOH ;  A5F2W3, DNLJ_VIBC3 ;
DR   Q9KTD1, DNLJ_VIBCH ;  C3LTL9, DNLJ_VIBCM ;  Q5E3L1, DNLJ_VIBF1 ;
DR   B5FGU7, DNLJ_VIBFM ;  A7MT54, DNLJ_VIBHB ;  Q87RJ4, DNLJ_VIBPA ;
DR   B7VIK3, DNLJ_VIBSL ;  Q8DFK5, DNLJ_VIBVU ;  Q7MMT5, DNLJ_VIBVY ;
DR   Q8D2B9, DNLJ_WIGBR ;  Q73H01, DNLJ_WOLPM ;  B3CPS1, DNLJ_WOLPP ;
DR   Q7M8A0, DNLJ_WOLSU ;  Q5GS88, DNLJ_WOLTR ;  C0R399, DNLJ_WOLWR ;
DR   Q8PM07, DNLJ_XANAC ;  Q3BV14, DNLJ_XANC5 ;  Q4UTB0, DNLJ_XANC8 ;
DR   B0RUY2, DNLJ_XANCB ;  Q8PAB5, DNLJ_XANCP ;  Q2P334, DNLJ_XANOM ;
DR   Q5H057, DNLJ_XANOR ;  A7IG64, DNLJ_XANP2 ;  B2I9S4, DNLJ_XYLF2 ;
DR   Q9PAG2, DNLJ_XYLFA ;  B0U5G7, DNLJ_XYLFM ;  Q87A88, DNLJ_XYLFT ;
DR   A1JLA4, DNLJ_YERE8 ;  A7FGC2, DNLJ_YERP3 ;  Q1C5X9, DNLJ_YERPA ;
DR   B2K917, DNLJ_YERPB ;  Q7CJF3, DNLJ_YERPE ;  A9QZH0, DNLJ_YERPG ;
DR   Q1CJV7, DNLJ_YERPN ;  A4TMG4, DNLJ_YERPP ;  Q668M6, DNLJ_YERPS ;
DR   B1JFZ0, DNLJ_YERPY ;  P28719, DNLJ_ZYMMO ;  C1DIC2, LIGB_AZOVD ;
DR   Q1QXD7, LIGB_CHRSD ;  A8ARN4, LIGB_CITK8 ;  A7ZTJ9, LIGB_ECO24 ;
DR   B7UM69, LIGB_ECO27 ;  B7MFK8, LIGB_ECO45 ;  B7L771, LIGB_ECO55 ;
DR   Q8XD89, LIGB_ECO57 ;  B5YWE6, LIGB_ECO5E ;  B7NQ11, LIGB_ECO7I ;
DR   B7N287, LIGB_ECO81 ;  B7M4D2, LIGB_ECO8A ;  C4ZXN9, LIGB_ECOBW ;
DR   B1X980, LIGB_ECODH ;  A8A6A9, LIGB_ECOHS ;  A1AHH8, LIGB_ECOK1 ;
DR   Q0TBG2, LIGB_ECOL5 ;  Q8FC83, LIGB_ECOL6 ;  B1IYV3, LIGB_ECOLC ;
DR   P25772, LIGB_ECOLI ;  B7NEV1, LIGB_ECOLU ;  B1LK84, LIGB_ECOSM ;
DR   Q1R4U5, LIGB_ECOUT ;  A4W502, LIGB_ENT38 ;  A7MQB5, LIGB_ENTS8 ;
DR   Q6DB58, LIGB_ERWCT ;  B5XTF0, LIGB_KLEP3 ;  A6TFP6, LIGB_KLEP7 ;
DR   C6DJC3, LIGB_PECCP ;  Q7N9N4, LIGB_PHOLL ;  Q1I3X5, LIGB_PSEE4 ;
DR   Q4K4I6, LIGB_PSEF5 ;  C3K3F7, LIGB_PSEFS ;  A4XPF7, LIGB_PSEMY ;
DR   A5WA01, LIGB_PSEP1 ;  Q3K5E7, LIGB_PSEPF ;  B0KLZ2, LIGB_PSEPG ;
DR   Q88D59, LIGB_PSEPK ;  B1J2Z7, LIGB_PSEPW ;  Q88AK8, LIGB_PSESM ;
DR   Q4ZLZ9, LIGB_PSEU2 ;  A4VRF3, LIGB_PSEU5 ;  B5EXF2, LIGB_SALA4 ;
DR   A9MKM6, LIGB_SALAR ;  Q57I94, LIGB_SALCH ;  B5FM71, LIGB_SALDC ;
DR   B5R5H2, LIGB_SALEP ;  B5RG75, LIGB_SALG2 ;  B4T9Z1, LIGB_SALHS ;
DR   B4SXE9, LIGB_SALNS ;  Q5PC41, LIGB_SALPA ;  A9MVP4, LIGB_SALPB ;
DR   C0Q1X9, LIGB_SALPC ;  B5BI22, LIGB_SALPK ;  B4TZZ8, LIGB_SALSV ;
DR   Q8ZL42, LIGB_SALTY ;  Q0SYH4, LIGB_SHIF8 ;  Q83PM9, LIGB_SHIFL ;
DR   Q3YW09, LIGB_SHISS ;  A1JHV9, LIGB_YERE8 ;  A7FCR5, LIGB_YERP3 ;
DR   Q1C259, LIGB_YERPA ;  B2JYM4, LIGB_YERPB ;  Q7CLB2, LIGB_YERPE ;
DR   A9R666, LIGB_YERPG ;  Q1CCZ4, LIGB_YERPN ;  A4TSE5, LIGB_YERPP ;
DR   Q66GE4, LIGB_YERPS ;  B1JQZ3, LIGB_YERPY ;  Q197A8, VF205_IIV3 ;
DR   Q91FW5, VF205_IIV6 ;
//
ID   6.5.1.3
DE   RNA ligase (ATP).
AN   Polyribonucleotide synthase (ATP).
AN   Ribonucleic ligase.
CA   ATP + (ribonucleotide)(n) + (ribonucleotide)(m) = AMP + diphosphate +
CA   (ribonucleotide)(n+m).
CC   -!- Converts linear RNA to a circular form by transfer of the
CC       5'-phosphate to the 3'-hydroxy terminus.
DR   P41476, PNKL_NPVAC ;  P86927, RLGM1_TRYB2;  P86926, RLGM1_TRYBB;
DR   P86925, RLGM2_TRYB2;  P86924, RLGM2_TRYBB;  P32277, RLIG2_BPT4 ;
DR   P00971, RLIG_BPT4  ;  B0WCT9, RTCB1_CULQU;  B0EAV2, RTCB1_ENTDI;
DR   C4M244, RTCB1_ENTHI;  B0XKF3, RTCB2_CULQU;  B0EIW5, RTCB2_ENTDI;
DR   C4M6T2, RTCB2_ENTHI;  Q17FP1, RTCB_AEDAE ;  Q7Q412, RTCB_ANOGA ;
DR   Q5E9T9, RTCB_BOVIN ;  C3YN79, RTCB_BRAFL ;  A8QC60, RTCB_BRUMA ;
DR   P90838, RTCB_CAEEL ;  A8JC00, RTCB_CHLRE ;  Q6NZS4, RTCB_DANRE ;
DR   Q54Y09, RTCB_DICDI ;  Q9VIW7, RTCB_DROME ;  Q9Y3I0, RTCB_HUMAN ;
DR   Q4R6X4, RTCB_MACFA ;  C1MI97, RTCB_MICPC ;  C1E9Y5, RTCB_MICSR ;
DR   A9UXG6, RTCB_MONBE ;  Q99LF4, RTCB_MOUSE ;  A7RKF6, RTCB_NEMVE ;
DR   A4S3S3, RTCB_OSTLU ;  Q00ZY2, RTCB_OSTTA ;  A9CB42, RTCB_PAPAN ;
DR   Q19PY3, RTCB_PIG   ;  Q4YUZ9, RTCB_PLABA ;  Q8IIU6, RTCB_PLAF7 ;
DR   B3L4K9, RTCB_PLAKH ;  Q7RI54, RTCB_PLAYO ;  Q6AYT3, RTCB_RAT   ;
DR   B8LBM8, RTCB_THAPS ;  Q4U923, RTCB_THEAN ;  Q4N1R8, RTCB_THEPA ;
DR   B3RID0, RTCB_TRIAD ;  Q561P3, RTCB_XENTR ;  P43075, TRNL_CANAL ;
DR   P09880, TRNL_YEAST ;
//
ID   6.5.1.4
DE   RNA-3'-phosphate cyclase.
AN   RNA 3'-terminal phosphate cyclase.
AN   RNA cyclase.
CA   ATP + RNA 3'-terminal-phosphate = AMP + diphosphate + RNA terminal-
CA   2',3'-cyclic-phosphate.
CC   -!- Adenosine 5'-(gamma-thio)triphosphate can act instead of ATP.
PR   PROSITE; PDOC00989;
DR   Q2HJ88, RTC1_BOVIN ;  O15746, RTC1_DICDI ;  O77264, RTC1_DROME ;
DR   O00442, RTC1_HUMAN ;  Q4R3J0, RTC1_MACFA ;  Q9D7H3, RTC1_MOUSE ;
DR   Q5R7P3, RTC1_PONAB ;  Q1IS76, RTCA_ACIBL ;  Q9YES0, RTCA_AERPE ;
DR   Q3M6L1, RTCA_ANAVT ;  O66884, RTCA_AQUAE ;  O28837, RTCA_ARCFU ;
DR   A8MAV7, RTCA_CALMQ ;  B7KCF3, RTCA_CYAP7 ;  B8D680, RTCA_DESK1 ;
DR   A7ZSU9, RTCA_ECO24 ;  B7UKC4, RTCA_ECO27 ;  B7MDP5, RTCA_ECO45 ;
DR   B7L4U9, RTCA_ECO55 ;  P58127, RTCA_ECO57 ;  B5YTX2, RTCA_ECO5E ;
DR   B7NMI4, RTCA_ECO7I ;  B7N1J7, RTCA_ECO81 ;  B7M2I0, RTCA_ECO8A ;
DR   C4ZVX1, RTCA_ECOBW ;  B1X765, RTCA_ECODH ;  A8A5M8, RTCA_ECOHS ;
DR   A1AGU3, RTCA_ECOK1 ;  Q0TC48, RTCA_ECOL5 ;  Q8FCS8, RTCA_ECOL6 ;
DR   B1IP46, RTCA_ECOLC ;  P46849, RTCA_ECOLI ;  B7NE24, RTCA_ECOLU ;
DR   B1LI80, RTCA_ECOSM ;  Q1R5L5, RTCA_ECOUT ;  B7LSC2, RTCA_ESCF3 ;
DR   B0R414, RTCA_HALS3 ;  Q9HRE8, RTCA_HALSA ;  A2BN21, RTCA_HYPBU ;
DR   A8A9W2, RTCA_IGNH4 ;  B1L6E9, RTCA_KORCO ;  Q8TH85, RTCA_METAC ;
DR   Q46DV9, RTCA_METBF ;  Q12V70, RTCA_METBU ;  Q609M1, RTCA_METCA ;
DR   Q60335, RTCA_METJA ;  Q8TZC9, RTCA_METKA ;  Q8PXC4, RTCA_METMA ;
DR   A4YEC3, RTCA_METS5 ;  O27937, RTCA_METTH ;  A0B532, RTCA_METTP ;
DR   Q2Y720, RTCA_NITMU ;  B2IWJ8, RTCA_NOSP7 ;  Q8YVS3, RTCA_NOSS1 ;
DR   B7V0C8, RTCA_PSEA8 ;  Q02G92, RTCA_PSEAB ;  Q9HVJ9, RTCA_PSEAE ;
DR   Q4KEB8, RTCA_PSEF5 ;  A4XRJ0, RTCA_PSEMY ;  Q9V0Z6, RTCA_PYRAB ;
DR   Q8ZST4, RTCA_PYRAE ;  A3MXQ7, RTCA_PYRCJ ;  Q8U0N7, RTCA_PYRFU ;
DR   O59198, RTCA_PYRHO ;  A1RSJ7, RTCA_PYRIL ;  Q5JIQ0, RTCA_PYRKO ;
DR   Q8Y2V6, RTCA_RALSO ;  B5F8N4, RTCA_SALA4 ;  B5R378, RTCA_SALEP ;
DR   B5R7J6, RTCA_SALG2 ;  B4TKU5, RTCA_SALHS ;  C0Q0J3, RTCA_SALPC ;
DR   Q8ZLI0, RTCA_SALTY ;  B2U3M8, RTCA_SHIB3 ;  Q31VL3, RTCA_SHIBS ;
DR   Q32AN4, RTCA_SHIDS ;  Q3YWK6, RTCA_SHISS ;  A3DN24, RTCA_STAMF ;
DR   Q4JB78, RTCA_SULAC ;  C3N179, RTCA_SULIA ;  C4KKE6, RTCA_SULIK ;
DR   C3MKC1, RTCA_SULIL ;  C3MU91, RTCA_SULIM ;  C3NMT8, RTCA_SULIN ;
DR   C3N969, RTCA_SULIY ;  Q97W04, RTCA_SULSO ;  Q974U1, RTCA_SULTO ;
DR   C5A2A3, RTCA_THEGJ ;  B1YDJ1, RTCA_THENV ;  B6YSJ5, RTCA_THEON ;
DR   C6A4N4, RTCA_THESM ;
//
ID   6.6.1.1
DE   Magnesium chelatase.
AN   Magnesium-chelatase.
AN   Magnesium-protoporphyrin chelatase.
AN   Magnesium-protoporphyrin IX chelatase.
AN   Mg-chelatase.
AN   Mg-protoporphyrin IX chelatase.
AN   Mg-protoporphyrin IX magnesio-lyase.
AN   Protoporphyrin IX magnesium-chelatase.
AN   Protoporphyrin IX Mg-chelatase.
CA   ATP + protoporphyrin IX + Mg(2+) + H(2)O = ADP + phosphate +
CA   Mg-protoporphyrin IX + 2 H(+).
CC   -!- This is the first committed step of chlorophyll biosynthesis and is a
CC       branchpoint of two major routes in the tetrapyrrole pathway.
DR   O50313, BCHD_CHLP8 ;  Q93SW0, BCHD_CHLTE ;  Q9ZGE6, BCHD_HELMO ;
DR   P26175, BCHD_RHOCB ;  O34845, BCHD_RHOS4 ;  O50314, BCHH_CHLP8 ;
DR   P26162, BCHH_RHOCB ;  Q9RFD5, BCHH_RHOS4 ;  Q9WXA9, BCHI_ACIRU ;
DR   O50312, BCHI_CHLP8 ;  Q93SW1, BCHI_CHLTE ;  P26239, BCHI_RHOCB ;
DR   O30819, BCHI_RHOS4 ;  P26174, BCHO_RHOCA ;  Q9SJE1, CHLD_ARATH ;
DR   O22437, CHLD_PEA   ;  O07345, CHLD_SYNE7 ;  P72772, CHLD_SYNY3 ;
DR   O24133, CHLD_TOBAC ;  Q44498, CHLI_ANAVA ;  P16127, CHLI_ARATH ;
DR   Q06J65, CHLI_BIGNA ;  Q94FT3, CHLI_CHLRE ;  P56304, CHLI_CHLVU ;
DR   Q9TLX7, CHLI_CYACA ;  P48101, CHLI_CYAPA ;  P31205, CHLI_EUGGR ;
DR   Q39516, CHLI_GUITH ;  Q9MUT3, CHLI_MESVI ;  Q9TL08, CHLI_NEPOL ;
DR   P58571, CHLI_NOSS1 ;  P49469, CHLI_ODOSI ;  Q32742, CHLI_OLILU ;
DR   P51394, CHLI_PORPU ;  Q1XD93, CHLI_PORYE ;  P93162, CHLI_SOYBN ;
DR   P51634, CHLI_SYNY3 ;  O22436, CHLI_TOBAC ;
//
ID   6.6.1.2
DE   Cobaltochelatase.
AN   Hydrogenobyrinic acid a,c-diamide cobaltochelatase.
CA   ATP + hydrogenobyrinic acid a,c-diamide + Co(2+) + H(2)O = ADP +
CA   phosphate + cob(II)yrinic acid a,c-diamide + H(2).
CC   -!- This enzyme, which forms part of the aerobic cobalamin biosynthesis
CC       pathway, is a type I chelatase, being heterotrimeric and ATP-
CC       dependent.
CC   -!- It comprises two components, one of which corresponds to CobN and the
CC       other is composed of two polypeptides, specified by cobS and cobT in
CC       Pseudomonas denitrificans, and named CobST.
CC   -!- Hydrogenobyrinic acid is a very poor substrate.
CC   -!- ATP can be replaced by dATP or CTP but the reaction proceeds more
CC       slowly.
CC   -!- CobN exhibits a high affinity for hydrogenobyrinic acid a,c-diamide.
CC   -!- The oligomeric protein CobST possesses at least one sulfhydryl group
CC       that is essential for ATP-binding.
CC   -!- Once the Co(2+) is inserted, the next step in the pathway ensures
CC       that the cobalt is ligated securely by reducing Co(II) to Co(I); this
CC       step is carried out by EC 1.16.8.1.
DR   Q9HZQ3, COBN_PSEAE ;  P29929, COBN_PSEDE ;  P29933, COBS_PSEDE ;
DR   P29934, COBT_PSEDE ;
//