BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0050.0123.p (307 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2109 [GER] COG0697 Permeases of the drug/metabolite transport... 403 e-112 yddG [GER] COG0697 Permeases of the drug/metabolite transporter ... 340 3e-93 ZyddG [GER] COG0697 Permeases of the drug/metabolite transporter... 340 3e-93 ECs2077 [GER] COG0697 Permeases of the drug/metabolite transport... 340 3e-93 STM1571 [GER] COG0697 Permeases of the drug/metabolite transport... 290 2e-78 >RSc2109 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 316 Score = 403 bits (1036), Expect = e-112, Method: Compositional matrix adjust. Identities = 208/313 (66%), Positives = 249/313 (79%), Gaps = 7/313 (2%) Query: 1 MNSKKATLVGLTAVVLWSAIVGLIRGVSEHLGATGGAAAIYTVASAILLVTVGMPRLRSF 60 + +KATL+GL AVVLWS+IVGL+RGVS LGA GGAA +YTV S LL +VG ++ +F Sbjct: 2 QSKRKATLIGLIAVVLWSSIVGLLRGVSASLGAVGGAAMMYTVVSIFLLFSVGFIKVNAF 61 Query: 61 PRRYLFWGSLLFVSYELCLSLSIGYANTARQAIEVGMVNYLWPTFTLTAAILFSKQRATW 120 PRRYL WGS+LFVSYELCLSLSIGYAN+ RQAIEVGMVNYLWPTFT+ AI F++Q + Sbjct: 62 PRRYLVWGSILFVSYELCLSLSIGYANSDRQAIEVGMVNYLWPTFTMLFAIAFNRQPSNL 121 Query: 121 LMAPGFVLSMLGICWVLGGDQGLDVAGMLENIRDNPLSYGLAFAGALIWAAYCTVTTRMA 180 L+ PG ++++LGIC VLGGDQGLD AGM NI+DNPLSYGLA +GALIWAAYC VT+RMA Sbjct: 122 LIIPGVLVAILGICQVLGGDQGLDFAGMAANIQDNPLSYGLALSGALIWAAYCAVTSRMA 181 Query: 181 AGMNGVTPFFMMVAVVLWGKVLAGGHLAELSMSLPALVYLLLAAAAMGLGYAAWNVGILH 240 G NG+T FFM+ A+ LW K LA G A + S A++YL++AA AMG GYAAWNVGILH Sbjct: 182 EGKNGITLFFMLTALALWIKYLATGGGA-MHFSYQAILYLVMAACAMGFGYAAWNVGILH 240 Query: 241 GNVTVLAGASYFIPVFSSALSALLLRSPLPSAFWIGAGLVCAGSILCWIATR------KA 294 GNVTVLAGASYFIPVFS+AL+A LLR+PL SAFW GA +VCAGSILCW+ATR + Sbjct: 241 GNVTVLAGASYFIPVFSAALAATLLRTPLSSAFWKGASMVCAGSILCWLATRGQRSTAPS 300 Query: 295 APGSARADAVQNL 307 +P AR A + + Sbjct: 301 SPERARWHAHERI 313 >yddG [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Eco Escherichia coli K12 Length = 293 Score = 340 bits (872), Expect = 3e-93, Method: Compositional matrix adjust. Identities = 169/293 (57%), Positives = 215/293 (73%), Gaps = 1/293 (0%) Query: 1 MNSKKATLVGLTAVVLWSAIVGLIRGVSEHLGATGGAAAIYTVASAILLVTVGMPRLRSF 60 M +KATL+GL A+VLWS +VGLIRGVSE LG GGAAAIY+++ +L+ TVG PR+R Sbjct: 1 MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLSGLLLIFTVGFPRIRQI 60 Query: 61 PRRYLFWGSLLFVSYELCLSLSIGYANTARQAIEVGMVNYLWPTFTLTAAILFSKQRATW 120 P+ YL GSLLFVSYE+CL+LS+GYA T QAIEVGMVNYLWP+ T+ AILF+ Q+ W Sbjct: 61 PKGYLLAGSLLFVSYEICLALSLGYAATHHQAIEVGMVNYLWPSLTILFAILFNGQKTNW 120 Query: 121 LMAPGFVLSMLGICWVLGGDQGLDVAGMLENIRDNPLSYGLAFAGALIWAAYCTVTTRMA 180 L+ PG +L+++G+CWVLGGD GL ++ NI +PLSY LAF GA IWAAYCTVT + A Sbjct: 121 LIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYFLAFIGAFIWAAYCTVTNKYA 180 Query: 181 AGMNGVTPFFMMVAVVLWGKVLAGGHLAELSMSLPALVYLLLAAAAMGLGYAAWNVGILH 240 G NG+T F ++ LW E+ S P ++ L+ AA +G YAAWNVGILH Sbjct: 181 RGFNGITVFVLLTGASLWVYYFLTPQ-PEMIFSTPVMIKLISAAFTLGFAYAAWNVGILH 239 Query: 241 GNVTVLAGASYFIPVFSSALSALLLRSPLPSAFWIGAGLVCAGSILCWIATRK 293 GNVT++A SYF PV SSAL+A+LL +PL +FW GA +VC GS+LCW+ATR+ Sbjct: 240 GNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGALMVCGGSLLCWLATRR 292 >ZyddG [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 293 Score = 340 bits (872), Expect = 3e-93, Method: Compositional matrix adjust. Identities = 169/293 (57%), Positives = 215/293 (73%), Gaps = 1/293 (0%) Query: 1 MNSKKATLVGLTAVVLWSAIVGLIRGVSEHLGATGGAAAIYTVASAILLVTVGMPRLRSF 60 M +KATL+GL A+VLWS +VGLIRGVSE LG GGAAAIY+++ +L+ TVG PR+R Sbjct: 1 MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLSGLLLIFTVGFPRIRQI 60 Query: 61 PRRYLFWGSLLFVSYELCLSLSIGYANTARQAIEVGMVNYLWPTFTLTAAILFSKQRATW 120 P+ YL GSLLFVSYE+CL+LS+GYA T QAIEVGMVNYLWP+ T+ AILF+ Q+ W Sbjct: 61 PKGYLLAGSLLFVSYEICLALSLGYAATRHQAIEVGMVNYLWPSLTILFAILFNGQKTNW 120 Query: 121 LMAPGFVLSMLGICWVLGGDQGLDVAGMLENIRDNPLSYGLAFAGALIWAAYCTVTTRMA 180 L+ PG +L+++G+CWVLGGD GL ++ NI +PLSY LAF GA IWAAYCTVT + A Sbjct: 121 LIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYFLAFIGAFIWAAYCTVTNKYA 180 Query: 181 AGMNGVTPFFMMVAVVLWGKVLAGGHLAELSMSLPALVYLLLAAAAMGLGYAAWNVGILH 240 G NG+T F ++ LW E+ S P ++ L+ AA +G YAAWNVGILH Sbjct: 181 RGFNGITVFVLLTGASLWVYYFLTPQ-PEMVFSTPVMIKLISAAFTLGFAYAAWNVGILH 239 Query: 241 GNVTVLAGASYFIPVFSSALSALLLRSPLPSAFWIGAGLVCAGSILCWIATRK 293 GNVT++A SYF PV SSAL+A+LL +PL +FW GA +VC GS+LCW+ATR+ Sbjct: 240 GNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGALMVCGGSLLCWLATRR 292 >ECs2077 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Ecs Escherichia coli O157:H7 Length = 293 Score = 340 bits (872), Expect = 3e-93, Method: Compositional matrix adjust. Identities = 169/293 (57%), Positives = 215/293 (73%), Gaps = 1/293 (0%) Query: 1 MNSKKATLVGLTAVVLWSAIVGLIRGVSEHLGATGGAAAIYTVASAILLVTVGMPRLRSF 60 M +KATL+GL A+VLWS +VGLIRGVSE LG GGAAAIY+++ +L+ TVG PR+R Sbjct: 1 MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLSGLLLIFTVGFPRIRQI 60 Query: 61 PRRYLFWGSLLFVSYELCLSLSIGYANTARQAIEVGMVNYLWPTFTLTAAILFSKQRATW 120 P+ YL GSLLFVSYE+CL+LS+GYA T QAIEVGMVNYLWP+ T+ AILF+ Q+ W Sbjct: 61 PKGYLLAGSLLFVSYEICLALSLGYAATRHQAIEVGMVNYLWPSLTILFAILFNGQKTNW 120 Query: 121 LMAPGFVLSMLGICWVLGGDQGLDVAGMLENIRDNPLSYGLAFAGALIWAAYCTVTTRMA 180 L+ PG +L+++G+CWVLGGD GL ++ NI +PLSY LAF GA IWAAYCTVT + A Sbjct: 121 LIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYFLAFIGAFIWAAYCTVTNKYA 180 Query: 181 AGMNGVTPFFMMVAVVLWGKVLAGGHLAELSMSLPALVYLLLAAAAMGLGYAAWNVGILH 240 G NG+T F ++ LW E+ S P ++ L+ AA +G YAAWNVGILH Sbjct: 181 RGFNGITVFVLLTGASLWVYYFLTPQ-PEMVFSTPVMIKLISAAFTLGFAYAAWNVGILH 239 Query: 241 GNVTVLAGASYFIPVFSSALSALLLRSPLPSAFWIGAGLVCAGSILCWIATRK 293 GNVT++A SYF PV SSAL+A+LL +PL +FW GA +VC GS+LCW+ATR+ Sbjct: 240 GNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGALMVCGGSLLCWLATRR 292 >STM1571 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sty Salmonella typhimurium LT2 Length = 274 Score = 290 bits (743), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 157/274 (57%), Positives = 200/274 (72%), Gaps = 1/274 (0%) Query: 20 IVGLIRGVSEHLGATGGAAAIYTVASAILLVTVGMPRLRSFPRRYLFWGSLLFVSYELCL 79 +VGLIRGVSE LG GGAA IY+++ +L+ TVG+P +R FP RYL GS+LFVSYE+CL Sbjct: 1 MVGLIRGVSEGLGPVGGAAMIYSLSGLLLIFTVGLPDIRRFPGRYLIAGSVLFVSYEICL 60 Query: 80 SLSIGYANTARQAIEVGMVNYLWPTFTLTAAILFSKQRATWLMAPGFVLSMLGICWVLGG 139 +LS+GYA T QAIEVGMVNYLWP+ T+ AILF+ Q+ WL+ PG ++++ G+CWVLGG Sbjct: 61 ALSLGYAATRHQAIEVGMVNYLWPSLTILFAILFNGQKTNWLIVPGLLIALTGVCWVLGG 120 Query: 140 DQGLDVAGMLENIRDNPLSYGLAFAGALIWAAYCTVTTRMAAGMNGVTPFFMMVAVVLWG 199 + GL+ ++ N+ +PLSY LAF GA IWA YCTVT + A G NG+T F ++ AV LW Sbjct: 121 ENGLNPGEIISNVATSPLSYLLAFLGAFIWATYCTVTNKYARGFNGITVFVLLTAVALWL 180 Query: 200 KVLAGGHLAELSMSLPALVYLLLAAAAMGLGYAAWNVGILHGNVTVLAGASYFIPVFSSA 259 A + SLP + L AA +G YAAWNVGILHGNVT++A SYF PV SSA Sbjct: 181 HYFLTPQPAMI-FSLPVIAKLFTAALTLGFAYAAWNVGILHGNVTIMAVGSYFTPVMSSA 239 Query: 260 LSALLLRSPLPSAFWIGAGLVCAGSILCWIATRK 293 L+ALLL SPL +FW GA +VC GS+LCW+ATR+ Sbjct: 240 LAALLLSSPLSFSFWQGAVMVCVGSLLCWLATRR 273