BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0050.0097.p (1027 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3535_1 [O] COG1404 Subtilisin-like serine proteases Pae Pseudo... 334 7e-91 NMA0478_1 [O] COG1404 Subtilisin-like serine proteases NmA Neiss... 119 4e-26 NMB1969_1 [O] COG1404 Subtilisin-like serine proteases Nme Neiss... 111 1e-23 XF0267_1 [O] COG1404 Subtilisin-like serine proteases Xfa Xylell... 106 3e-22 XF1026_1 [O] COG1404 Subtilisin-like serine proteases Xfa Xylell... 105 5e-22 >PA3535_1 [O] COG1404 Subtilisin-like serine proteases Pae Pseudomonas aeruginosa Length = 453 Score = 334 bits (856), Expect = 7e-91, Method: Compositional matrix adjust. Identities = 177/388 (45%), Positives = 248/388 (63%), Gaps = 21/388 (5%) Query: 44 AEFKADWGLGAMNAQYAYVAGYTGQGIKLGAVDSGLLLTHNEFARRNVKALAVTGAYAND 103 AE++ DWGL M A AY AG GQG+K+G +DSG +H + + + +G Y + Sbjct: 47 AEYQQDWGLERMRADQAYAAGIDGQGVKIGEMDSGFDPSHPDTPASRYQPVTASGTYVD- 105 Query: 104 GYQYQDGSQAWKAGDAFNIPGALSPLNDKHGSHVSGTIAAAKNGDGIMGVAFASDYYITN 163 G F++ GA++ ND HG+HV GT+ A+++G G+ GVA+A+ Y+ N Sbjct: 106 -------------GTPFSVSGAMNGNNDSHGTHVGGTLGASRDGVGMHGVAYAAQVYVAN 152 Query: 164 TNGTDSSVYGVNMDYNYFKAAYGNLASAGVRAINSSWGNPDSRDDFGSISGVAAAYQRLQ 223 TN DS ++G D NYFKAAY LA AGVRAIN+SWG+ + ++ G+ AAY Q Sbjct: 153 TNQNDSFLFGPTPDPNYFKAAYQALADAGVRAINNSWGSQPKDVSYETLDGLHAAY--AQ 210 Query: 224 GGGKKSWLDAAADVAQASNTLLVWAAGNASKANVNIRSALPYFRPELEQNWIAVAALNTS 283 G+ +WLDAAA V++ + V++AGN+ AN ++RSALPYF+P+LE +W+AV+ L+ Sbjct: 211 HYGRSTWLDAAAGVSR-QGVINVFSAGNSGYANASVRSALPYFQPDLEGHWLAVSGLDQQ 269 Query: 284 SMLPSFSNQCGLAKYWCVSAPGSGITSLNITSDTALVNASGTSMAAPHVTGALGVLMQRY 343 + N+CG+AKYWC++ PG I S N SGTSMAAPH TGAL ++MQRY Sbjct: 270 NG--QRYNRCGIAKYWCITTPGRLINS--TMPGGGYANKSGTSMAAPHATGALALVMQRY 325 Query: 344 PDLDNQAIRTILLSTAKHLGTGAADVPNTMFGWGLPDLNKALYGPGQLLGVFKANIAAGS 403 P L+N+ +LL+TA L P GWG+PDL +A++GPGQLLG F+AN+ AG Sbjct: 326 PYLNNEQALQVLLTTATQLDGTPTGAPTDTVGWGVPDLGRAMHGPGQLLGRFEANLPAGL 385 Query: 404 TDTWSNDISEAALVQRKSEDKAQLAAWQ 431 D WSN IS++AL+QR++ED A+ AAWQ Sbjct: 386 RDEWSNPISDSALLQRQAEDAAEHAAWQ 413 >NMA0478_1 [O] COG1404 Subtilisin-like serine proteases NmA Neisseria meningitidis Z2491 Length = 604 Score = 119 bits (298), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 119/434 (27%), Positives = 198/434 (45%), Gaps = 76/434 (17%) Query: 55 MNAQYAYVAGYTGQGIKLGAVDSGLLLTHNEFARRNVKALAVTGAYANDGYQYQDGSQAW 114 +N + A AGYTG+G+++G VD+G +V +++ Y + Y + + + Sbjct: 117 INLKPAIEAGYTGRGVEVGIVDTG----------ESVGSISFPELYGRKEHGYNENYKNY 166 Query: 115 KA---------GDAFNIPGAL----------SPLNDKHGSHVSGT-----IAAAKNGDG- 149 A GD +I + P + +H + I ++ DG Sbjct: 167 TAYMRKEAPEDGDGKDIEASFDDEAVIETEAKPTDIRHVKEIGHIDVVSHIIGGRSVDGR 226 Query: 150 -IMGVAFASDYYITNT-NGTDSSVYGVNMDYNYFKAAYGNLASAGVRAINSSWGNPDSR- 206 G+A + +I NT +GT + + + + A+ L GVR +N+S+G SR Sbjct: 227 PAGGIAPDATLHIMNTHDGTKNEIMSAAI-----RNAWVKLGERGVRIVNNSFGTT-SRA 280 Query: 207 ---DDFGSISGVAAAYQR---LQGGGKKSWLDAAADVAQAS------------NTLLVWA 248 D F I+ Y++ GG K+ D + Q S N L +++ Sbjct: 281 GTADHF-QIANSEEQYRQALLAYSGGDKT--DEGIRLMQQSDYGNLSYHIRNKNMLFIFS 337 Query: 249 AGNASKANVNIRSALPYFRPELEQNWIAVAALNTSSMLPSFSNQCGLAKYWCVSAPGSGI 308 A N ++A N + LP++ + ++ I VA ++ S + SN CG+ WC+SAP Sbjct: 338 ASNDAQAQPNTLTLLPFYEKDAQKGIITVAGVDRSGEKFNGSNHCGITAMWCLSAPYE-- 395 Query: 309 TSLNITSDTALVNASGTSMAAPHVTGALGVLMQRYPDLDNQAIRTILLSTAKHLGTGAAD 368 S+ T T + +GTS +AP VTG +L+Q+YP + N +RT LL+TA+ +G D Sbjct: 396 ASVRFTR-TNPIQIAGTSFSAPIVTGTAALLLQKYPWMSNDNLRTTLLTTAQDIGAVGVD 454 Query: 369 VPNTMFGWGLPDLNKALYGPGQL-LGVFKANIAAGSTD---TWSNDISEAALVQRKSEDK 424 + FGWGL D KA+ GP G F A+ G++D ++ NDIS + +K + Sbjct: 455 ---SKFGWGLLDTGKAMNGPASFPFGDFTAD-TKGTSDIAYSFRNDISGTGGLIKKGGSQ 510 Query: 425 AQLAAWQALSASTL 438 QL + T+ Sbjct: 511 LQLHGNNTYTGKTV 524 >NMB1969_1 [O] COG1404 Subtilisin-like serine proteases Nme Neisseria meningitidis MC58 Length = 618 Score = 111 bits (277), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 116/446 (26%), Positives = 192/446 (43%), Gaps = 86/446 (19%) Query: 55 MNAQYAYVAGYTGQGIKLGAVDSGLLLTHNEFARRNVKALAVTGAYANDGYQYQDGSQAW 114 +N + A AGYTG+G+++G VD+G +V +++ Y + Y + + + Sbjct: 117 INLKPAIEAGYTGRGVEVGIVDTG----------ESVGSISFPELYGRKEHGYNENYKNY 166 Query: 115 KA-------------------GDAFNIPGALSPLNDKHGSHVSGT-----IAAAKNGDG- 149 A D I P + +H + I ++ DG Sbjct: 167 TAYMRKEAPEDGGGKDIEASFDDEAVIETEAKPTDIRHVKEIGHIDLVSHIIGGRSVDGR 226 Query: 150 -IMGVAFASDYYITNTNGTDSSVYGVNMDYNYFKAAYGNLASAGVRAINSSWGNPDSRDD 208 G+A + +I NTN + M + A+ L GVR +N+S+G SR Sbjct: 227 PAGGIAPDATLHIMNTNDETKN----EMMVAAIRNAWVKLGERGVRIVNNSFGTT-SRAG 281 Query: 209 FGSISGVAAAYQRLQ------GGGKKSWLDAAADVAQAS------------NTLLVWAAG 250 + +A + ++ + GG K+ D + Q S N L +++ G Sbjct: 282 TADLFQIANSEEQYRQALLDYSGGDKT--DEGIRLMQQSDYGNLSYHIRNKNMLFIFSTG 339 Query: 251 NASKANVNIRSALPYFRPELEQNWIAVAALNTSSM--------------LPSFSNQCGLA 296 N ++A N + LP++ + ++ I VA ++ S L SN CG+ Sbjct: 340 NDAQAQPNTYALLPFYEKDAQKGIITVAGVDRSGEKFKREMYGEPGTEPLEYGSNHCGIT 399 Query: 297 KYWCVSAPGSGITSLNITSDTALVNASGTSMAAPHVTGALGVLMQRYPDLDNQAIRTILL 356 WC+SAP S+ T T + +GTS +AP VTG +L+Q+YP + N +RT LL Sbjct: 400 AMWCLSAPYE--ASVRFTR-TNPIQIAGTSFSAPIVTGTAALLLQKYPWMSNDNLRTTLL 456 Query: 357 STAKHLGTGAADVPNTMFGWGLPDLNKALYGPGQL-LGVFKANIAAGSTD---TWSNDIS 412 +TA+ +G D + FGWGL D KA+ GP G F A+ G++D ++ NDIS Sbjct: 457 TTAQDIGAVGVD---SKFGWGLLDAGKAMNGPASFPFGDFTAD-TKGTSDIAYSFRNDIS 512 Query: 413 EAALVQRKSEDKAQLAAWQALSASTL 438 + +K + QL + T+ Sbjct: 513 GTGGLIKKGGSQLQLHGNNTYTGKTI 538 >XF0267_1 [O] COG1404 Subtilisin-like serine proteases Xfa Xylella fastidiosa 9a5c Length = 471 Score = 106 bits (265), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 115/416 (27%), Positives = 178/416 (42%), Gaps = 85/416 (20%) Query: 44 AEFKADWGLGAMNAQYAYVAGYTGQGIKLGAVDSGL----LLTHNEFARRNVKALAVTGA 99 A+F+ L N + A+ G+TG+G +G VDSG+ + H++ NV A Sbjct: 10 AKFRVH--LDGTNTEPAHTLGFTGKGYMIGVVDSGVNRNHVTLHDKVVHNNVYVDYQDPA 67 Query: 100 YANDGYQYQDGSQAWKAGDAFNI-PGALSPLNDKHGSHVSGTIAAAKNGDGIMGVAFASD 158 +D + AG PG ++P + V + AA G +G F Sbjct: 68 SPDDVSGHGTNVAQLIAGQPVEYWPGGIAPGATIFSARVFSS-AAENAKQGPIGGNFFE- 125 Query: 159 YYITNTNGTDSSVYGVNMDYNYFKAAYGNLASAGVRAINSSWGNPDSRDDFGSISGVAAA 218 G + + VN D + +AGVR N+SWG Sbjct: 126 -------GEAAQLKRVNAD----------MIAAGVRIQNNSWG----------------- 151 Query: 219 YQRLQGGGKKSWLDAAA---------DVAQASNTLLVWAAGNASKANVNIRSALPYFRP- 268 Y+ G K+ W+D A D +N L+++A+GN S+ S LP Sbjct: 152 YENQNTGDKQVWIDPAVTDAFVNVYRDFVLNNNGLVIFASGNYSQQQPGRLSRLPSLPTV 211 Query: 269 -------ELEQNWIAVAALNTSS---MLPSFSNQCGLAKYWCVSAPGS------GITSLN 312 +LE+ W+ VAAL++ L S+SN CG+A ++C++APG +T+ Sbjct: 212 EGGASPADLERGWLVVAALDSFDHPDQLTSYSNHCGIAMHYCLAAPGDLIEIDPNVTTSP 271 Query: 313 ITSDTALVNA----SGTSMAAPHVTGALGVLMQRYPDLDNQAIRTILLSTAKHLGTGAAD 368 + D +N +GTS AAP V+GA ++ + +P N +R LL TA LG D Sbjct: 272 VDGDKGYLNGYLIQNGTSFAAPLVSGAAALVWEAFPYFSNDLVRQTLLGTATDLGAPGVD 331 Query: 369 VPNTMFGWGLPDLNKALYGPGQLLGVFKANIAAGSTD----TWSNDIS-EAALVQR 419 +FG+G ++ KA+ GP + F S D TW NDI+ L++R Sbjct: 332 ---EVFGYGALNVGKAVLGPAK----FDWGDVQVSFDDRRSTWGNDITGSGGLIKR 380 >XF1026_1 [O] COG1404 Subtilisin-like serine proteases Xfa Xylella fastidiosa 9a5c Length = 466 Score = 105 bits (263), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 111/411 (27%), Positives = 177/411 (43%), Gaps = 80/411 (19%) Query: 44 AEFKADWGLGAMNAQYAYVAGYTGQGIKLGAVDSGL----LLTHNEFARRNVKALAVTGA 99 A+F+ L N + A G+TG+G +G VDSG+ + HN+ NV A Sbjct: 10 AKFRVH--LDGTNTEPARTLGFTGKGYMIGVVDSGVNRNHVTLHNQVIHNNVYVDYQDPA 67 Query: 100 YANDGYQYQDGSQAWKAGDAFNI-PGALSPLNDKHGSHVSGTIAAAKNGDGIMGVAFASD 158 ++D + AG PG ++P + V + A + I G F + Sbjct: 68 SSDDVSGHGTNVAQLIAGQPVEYWPGGIAPGATIFSARVFSSAAESAKEGSISGNFFERE 127 Query: 159 YYITNTNGTDSSVYGVNMDYNYFKAAYGNLASAGVRAINSSWGNPDSRDDFGSISGVAAA 218 + + VN D + +AGVR N+SWG Sbjct: 128 ---------TAQLKRVNAD----------MIAAGVRIQNNSWG----------------- 151 Query: 219 YQRLQGGGKKSW---------LDAAADVAQASNTLLVWAAGNASKANVNIRSALPYFRP- 268 Y+ GG+ W ++A D +N L+V+A+GN ++ + LP Sbjct: 152 YESEDTGGEPVWRSPITTGLFVNAYRDFVLNNNGLVVFASGNEAQPQPGQLARLPSLPTV 211 Query: 269 -------ELEQNWIAVAALNTSS---MLPSFSNQCGLAKYWCVSAPGSGITSLNITSDTA 318 +LE+ W+ VAAL++ L S+SN CG+A ++C++APG + N ++++ Sbjct: 212 EGGASPADLERGWLVVAALDSFDHPDQLTSYSNHCGIAMHYCLAAPGDVVVIHNSVTNSS 271 Query: 319 LVNAS-----GTSMAAPHVTGALGVLMQRYPDLDNQAIRTILLSTAKHLGTGAADVPNTM 373 V+ GTS AAP V+GA ++ + +P N +R LL TA LG D + Sbjct: 272 SVDDEYYELQGTSFAAPLVSGAAALVWEAFPYFSNDLVRQTLLGTATDLGVPGVD---EV 328 Query: 374 FGWGLPDLNKALYGPGQLLGVFKANIAAGSTD----TWSNDIS-EAALVQR 419 FG+G ++ KA+ GP + F S D TW NDI+ L++R Sbjct: 329 FGYGALNVGKAVLGPAK----FDWGDVQVSFDDRRSTWGNDITGSGGLIKR 375