BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0050.0067.p (405 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1010 [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase... 526 e-149 PA3139 [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase ... 495 e-140 tyrB [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase Ec... 432 e-121 ZtyrB [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase E... 431 e-120 ECs5036 [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase... 431 e-120 >RSc1010 [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase Rso Ralstonia solanacearum Length = 398 Score = 526 bits (1354), Expect = e-149, Method: Compositional matrix adjust. Identities = 265/398 (66%), Positives = 309/398 (77%), Gaps = 1/398 (0%) Query: 8 SLFSAIEMAPRDPILGVTEAYNADQNPAKTNLGVGVYYDDNGKVPLLECVKKAEAELAAK 67 SLFSA+E+APRDPILG+ EA+NAD K NLGVGVY+ D GK+P+L V++AE A Sbjct: 2 SLFSAVELAPRDPILGLNEAFNADARSTKVNLGVGVYFTDEGKIPVLRAVQEAEKARLAM 61 Query: 68 LAPRTYLPIDGLATYDRAVQELVFGAGSAVVTEKRAITVQALGGTGALKLGADFLKHFSP 127 APR YLPI+G+A YD+AVQ+L+FGA S ++ E R +T QALGGTGALK+GADFLK P Sbjct: 62 AAPRGYLPIEGIAAYDQAVQKLLFGADSPLLAEGRVVTAQALGGTGALKIGADFLKRLYP 121 Query: 128 AGTEVWISDPSWENHRALFEMAGFKVNAYPYYDPATRGVNFAGMLDALKTMKSGSVVLLH 187 +V ISDPSWENHRALFE AGF V YPYYD T G+NFA ML+AL ++V+LH Sbjct: 122 -DAKVAISDPSWENHRALFEAAGFPVVNYPYYDAPTHGLNFAAMLEALNGYAPNTIVVLH 180 Query: 188 ACCHNPTGADLTDDQWTQVIEVVTSRGLVPFLDMAYQGFGDGIAEDGQVVRRFAEAGGPL 247 ACCHNPTG DLT +QW QV+EV+ ++ L+PFLDMAYQGF DGIA+DG V FAE+G Sbjct: 181 ACCHNPTGVDLTTEQWKQVVEVIKAKQLIPFLDMAYQGFADGIAQDGLAVSLFAESGLQF 240 Query: 248 FVSNSFSKSFSLYGERVGALSIAAASAEEAARVLSQLKRVVRTNYSNPPIHGGQVVATAL 307 FVS+SFSKSFSLYGERVGALSI S +EAARV+SQ+KRV+RTNYSNPP HGG VVA+ L Sbjct: 241 FVSSSFSKSFSLYGERVGALSIVTTSKDEAARVMSQVKRVIRTNYSNPPTHGGTVVASVL 300 Query: 308 ASPELRKLWEDELAEMRVRIREMRQLLVAKLKEKAPGHDFDFVIKQRGMFSYSGLTKAQV 367 SPELR +WE EL EMR RI+ MR LV KL K DF FV QRGMFSYSGL+ AQV Sbjct: 301 TSPELRAMWEQELGEMRDRIKSMRHALVDKLAAKGVKTDFSFVKAQRGMFSYSGLSAAQV 360 Query: 368 DRLRNEFSIYAVDTGRICVAALNTKNIDVVVDAIAKVL 405 DRLRNE IYAV TGRICVAALN+ NID VV+AIA+VL Sbjct: 361 DRLRNEHGIYAVSTGRICVAALNSHNIDAVVNAIAEVL 398 >PA3139 [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase Pae Pseudomonas aeruginosa Length = 398 Score = 495 bits (1274), Expect = e-140, Method: Compositional matrix adjust. Identities = 250/398 (62%), Positives = 300/398 (75%), Gaps = 1/398 (0%) Query: 8 SLFSAIEMAPRDPILGVTEAYNADQNPAKTNLGVGVYYDDNGKVPLLECVKKAEAELAAK 67 SLFSA+EMAPRDPILG+ EA+NAD P K NLGVGVYY++ G++PLL V+ AE Sbjct: 2 SLFSAVEMAPRDPILGLNEAFNADTRPGKINLGVGVYYNEEGRIPLLRAVQAAEKARIEA 61 Query: 68 LAPRTYLPIDGLATYDRAVQELVFGAGSAVVTEKRAITVQALGGTGALKLGADFLKHFSP 127 APR YLPI+G+A YD+ VQ+L+FG S ++ R +T QA+GGTGALKLGADFLK P Sbjct: 62 HAPRGYLPIEGIAAYDQGVQKLLFGNESELLAAGRVVTTQAVGGTGALKLGADFLKRLLP 121 Query: 128 AGTEVWISDPSWENHRALFEMAGFKVNAYPYYDPATRGVNFAGMLDALKTMKSGSVVLLH 187 T V ISDPSWENHRALFE AGF V Y YYD A+ GVN AG+L+ L + + S+V+LH Sbjct: 122 DAT-VAISDPSWENHRALFEAAGFPVQNYRYYDAASNGVNRAGLLEDLNALPARSIVVLH 180 Query: 188 ACCHNPTGADLTDDQWTQVIEVVTSRGLVPFLDMAYQGFGDGIAEDGQVVRRFAEAGGPL 247 ACCHNPTG DL D W QV++V+ ++G VPFLD+AYQGFG+GI ED VR FA++G Sbjct: 181 ACCHNPTGVDLELDDWKQVLDVLKAKGHVPFLDIAYQGFGNGIEEDAAAVRLFAQSGLSF 240 Query: 248 FVSNSFSKSFSLYGERVGALSIAAASAEEAARVLSQLKRVVRTNYSNPPIHGGQVVATAL 307 FVS+SFSKSFSLYGERVGALSI S +E+ARVLSQ+KRV+RTNYSNPP HG VV++ L Sbjct: 241 FVSSSFSKSFSLYGERVGALSIVTESRDESARVLSQVKRVIRTNYSNPPTHGASVVSSVL 300 Query: 308 ASPELRKLWEDELAEMRVRIREMRQLLVAKLKEKAPGHDFDFVIKQRGMFSYSGLTKAQV 367 SPELR LWE EL EMR RIR+MR +V +L DF FV +QRGMFSYSGLT QV Sbjct: 301 NSPELRALWEQELGEMRDRIRDMRLAMVEQLAAHGAKRDFSFVGRQRGMFSYSGLTADQV 360 Query: 368 DRLRNEFSIYAVDTGRICVAALNTKNIDVVVDAIAKVL 405 +RL+ EF IYAV TGRICVAALN N++ + AI +VL Sbjct: 361 ERLKTEFGIYAVSTGRICVAALNKSNLETITKAIVQVL 398 >tyrB [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase Eco Escherichia coli K12 Length = 397 Score = 432 bits (1111), Expect = e-121, Method: Compositional matrix adjust. Identities = 210/398 (52%), Positives = 271/398 (68%), Gaps = 2/398 (0%) Query: 9 LFSAIEMAPRDPILGVTEAYNADQNPAKTNLGVGVYYDDNGKVPLLECVKKAEAELAAK- 67 +F ++ DPIL + E + D K NL +G+YY+++G +P L+ V +AEA L A+ Sbjct: 1 MFQKVDAYAGDPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIPQLQAVAEAEARLNAQP 60 Query: 68 LAPRTYLPIDGLATYDRAVQELVFGAGSAVVTEKRAITVQALGGTGALKLGADFLKHFSP 127 YLP++GL Y A+ L+FGA V+ ++R T+Q LGG+GALK+GADFLK + P Sbjct: 61 HGASLYLPMEGLNCYRHAIAPLLFGADHPVLKQQRVATIQTLGGSGALKVGADFLKRYFP 120 Query: 128 AGTEVWISDPSWENHRALFEMAGFKVNAYPYYDPATRGVNFAGMLDALKTMKSGSVVLLH 187 + VW+SDP+WENH A+F AGF+V+ YP+YD AT GV F +L LKT+ + S+VLLH Sbjct: 121 E-SGVWVSDPTWENHVAIFAGAGFEVSTYPWYDEATNGVRFNDLLATLKTLPARSIVLLH 179 Query: 188 ACCHNPTGADLTDDQWTQVIEVVTSRGLVPFLDMAYQGFGDGIAEDGQVVRRFAEAGGPL 247 CCHNPTGADLT+DQW VIE++ +R L+PFLD+AYQGFG G+ ED +R A AG P Sbjct: 180 PCCHNPTGADLTNDQWDAVIEILKARELIPFLDIAYQGFGAGMEEDAYAIRAIASAGLPA 239 Query: 248 FVSNSFSKSFSLYGERVGALSIAAASAEEAARVLSQLKRVVRTNYSNPPIHGGQVVATAL 307 VSNSFSK FSLYGERVG LS+ AE A RVL QLK VR NYS+PP G QVVA L Sbjct: 240 LVSNSFSKIFSLYGERVGGLSVMCEDAEAAGRVLGQLKATVRRNYSSPPNFGAQVVAAVL 299 Query: 308 ASPELRKLWEDELAEMRVRIREMRQLLVAKLKEKAPGHDFDFVIKQRGMFSYSGLTKAQV 367 L+ W E+ EMR RI MRQ LV L + P +FD+++ QRGMFSY+GL+ AQV Sbjct: 300 NDEALKASWLAEVEEMRTRILAMRQELVKVLSTEMPERNFDYLLNQRGMFSYTGLSAAQV 359 Query: 368 DRLRNEFSIYAVDTGRICVAALNTKNIDVVVDAIAKVL 405 DRLR EF +Y + +GR+CVA LNT N+ V A A V+ Sbjct: 360 DRLREEFGVYLIASGRMCVAGLNTANVQRVAKAFAAVM 397 >ZtyrB [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase EcZ Escherichia coli O157:H7 EDL933 Length = 397 Score = 431 bits (1108), Expect = e-120, Method: Compositional matrix adjust. Identities = 210/398 (52%), Positives = 271/398 (68%), Gaps = 2/398 (0%) Query: 9 LFSAIEMAPRDPILGVTEAYNADQNPAKTNLGVGVYYDDNGKVPLLECVKKAEAEL-AAK 67 +F ++ DPIL + E + D K NL +G+YY+++G +P L+ V +AEA L A Sbjct: 1 MFQKVDAYAGDPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIPQLKAVAEAEARLNAVP 60 Query: 68 LAPRTYLPIDGLATYDRAVQELVFGAGSAVVTEKRAITVQALGGTGALKLGADFLKHFSP 127 YLP++GL +Y A+ L+FGA V+ ++R T+Q LGG+GALK+GADFLK + P Sbjct: 61 HGASLYLPMEGLNSYRHAIAPLLFGADHPVLQQQRVATIQTLGGSGALKVGADFLKRYFP 120 Query: 128 AGTEVWISDPSWENHRALFEMAGFKVNAYPYYDPATRGVNFAGMLDALKTMKSGSVVLLH 187 + VW+SDP+WENH A+F AGF+V+ YP+YD AT GV F +L LKT+ + S+VLLH Sbjct: 121 E-SGVWVSDPTWENHVAIFAGAGFEVSTYPWYDEATNGVRFNDLLAMLKTLPARSIVLLH 179 Query: 188 ACCHNPTGADLTDDQWTQVIEVVTSRGLVPFLDMAYQGFGDGIAEDGQVVRRFAEAGGPL 247 CCHNPTGADLT+DQW VIE++ +R L+PFLD+AYQGFG G+ ED +R A AG P Sbjct: 180 PCCHNPTGADLTNDQWDAVIEILKARELIPFLDIAYQGFGAGMEEDAYAIRAIASAGLPA 239 Query: 248 FVSNSFSKSFSLYGERVGALSIAAASAEEAARVLSQLKRVVRTNYSNPPIHGGQVVATAL 307 VSNSFSK FSLYGERVG LS+ AE A RVL QLK VR NYS+PP G QVVA L Sbjct: 240 LVSNSFSKIFSLYGERVGGLSVLCEDAEAAGRVLGQLKATVRRNYSSPPNFGAQVVAAVL 299 Query: 308 ASPELRKLWEDELAEMRVRIREMRQLLVAKLKEKAPGHDFDFVIKQRGMFSYSGLTKAQV 367 L+ W E+ EMR RI MRQ LV L + P +FD+++ QRGMFSY+GL+ AQV Sbjct: 300 NDEALKASWLAEVEEMRTRILAMRQELVKVLSTEMPERNFDYLLNQRGMFSYTGLSAAQV 359 Query: 368 DRLRNEFSIYAVDTGRICVAALNTKNIDVVVDAIAKVL 405 DRLR EF +Y + +GR+CVA LNT N+ V A A V+ Sbjct: 360 DRLREEFGVYLIASGRMCVAGLNTANVQRVAKAFAAVM 397 >ECs5036 [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase Ecs Escherichia coli O157:H7 Length = 397 Score = 431 bits (1108), Expect = e-120, Method: Compositional matrix adjust. Identities = 210/398 (52%), Positives = 271/398 (68%), Gaps = 2/398 (0%) Query: 9 LFSAIEMAPRDPILGVTEAYNADQNPAKTNLGVGVYYDDNGKVPLLECVKKAEAEL-AAK 67 +F ++ DPIL + E + D K NL +G+YY+++G +P L+ V +AEA L A Sbjct: 1 MFQKVDAYAGDPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIPQLKAVAEAEARLNAVP 60 Query: 68 LAPRTYLPIDGLATYDRAVQELVFGAGSAVVTEKRAITVQALGGTGALKLGADFLKHFSP 127 YLP++GL +Y A+ L+FGA V+ ++R T+Q LGG+GALK+GADFLK + P Sbjct: 61 HGASLYLPMEGLNSYRHAIAPLLFGADHPVLQQQRVATIQTLGGSGALKVGADFLKRYFP 120 Query: 128 AGTEVWISDPSWENHRALFEMAGFKVNAYPYYDPATRGVNFAGMLDALKTMKSGSVVLLH 187 + VW+SDP+WENH A+F AGF+V+ YP+YD AT GV F +L LKT+ + S+VLLH Sbjct: 121 E-SGVWVSDPTWENHVAIFAGAGFEVSTYPWYDEATNGVRFNDLLAMLKTLPARSIVLLH 179 Query: 188 ACCHNPTGADLTDDQWTQVIEVVTSRGLVPFLDMAYQGFGDGIAEDGQVVRRFAEAGGPL 247 CCHNPTGADLT+DQW VIE++ +R L+PFLD+AYQGFG G+ ED +R A AG P Sbjct: 180 PCCHNPTGADLTNDQWDAVIEILKARELIPFLDIAYQGFGAGMEEDAYAIRAIASAGLPA 239 Query: 248 FVSNSFSKSFSLYGERVGALSIAAASAEEAARVLSQLKRVVRTNYSNPPIHGGQVVATAL 307 VSNSFSK FSLYGERVG LS+ AE A RVL QLK VR NYS+PP G QVVA L Sbjct: 240 LVSNSFSKIFSLYGERVGGLSVLCEDAEAAGRVLGQLKATVRRNYSSPPNFGAQVVAAVL 299 Query: 308 ASPELRKLWEDELAEMRVRIREMRQLLVAKLKEKAPGHDFDFVIKQRGMFSYSGLTKAQV 367 L+ W E+ EMR RI MRQ LV L + P +FD+++ QRGMFSY+GL+ AQV Sbjct: 300 NDEALKASWLAEVEEMRTRILAMRQELVKVLSTEMPERNFDYLLNQRGMFSYTGLSAAQV 359 Query: 368 DRLRNEFSIYAVDTGRICVAALNTKNIDVVVDAIAKVL 405 DRLR EF +Y + +GR+CVA LNT N+ V A A V+ Sbjct: 360 DRLREEFGVYLIASGRMCVAGLNTANVQRVAKAFAAVM 397