BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0050.0061.p (421 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0828 [GEPR] COG0477 Permeases of the major facilitator superf... 593 e-169 Z4105 [GEPR] COG0477 Permeases of the major facilitator superfam... 590 e-168 ECs3649 [GEPR] COG0477 Permeases of the major facilitator superf... 590 e-168 BS_ycbE [GEPR] COG0477 Permeases of the major facilitator superf... 589 e-168 ygcZ [GEPR] COG0477 Permeases of the major facilitator superfami... 587 e-167 >RSp0828 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 450 Score = 593 bits (1530), Expect = e-169, Method: Compositional matrix adjust. Identities = 289/419 (68%), Positives = 353/419 (84%) Query: 1 LFVVTTVNYADRATLSIAGSAMKTELSLDPVMMGYIFSAFSWAYVLAQLPGGWLLDRFGS 60 LF+VTT+NYADRAT+S+AGSAM+ +L +D V +GYIFSAF WAYV+AQ+PGGWLLDRFGS Sbjct: 30 LFIVTTINYADRATISMAGSAMQKDLGIDAVSLGYIFSAFGWAYVIAQIPGGWLLDRFGS 89 Query: 61 KKIYMWSIALWSVFTFLQAGVTWMSTAAAVASLFLLRFMVGLAEAPSFPANGRIVAAWFP 120 +++Y +SI LWS+FT +Q + + + AA+ +F LRFMVG+AEAPSFPAN RIVAAWFP Sbjct: 90 RRVYSFSILLWSLFTLMQGTIGFFTGMAAIVLVFFLRFMVGVAEAPSFPANSRIVAAWFP 149 Query: 121 TKERGTASAIFNSAQYFAAVLFTPLMAWIVHTYSWHHVFTVMGVVGIALALIWGRIIYSP 180 ERGTASAIFNSAQY A V+F PLMAW+VH + WH+VF VMGV+GI +AL W R ++ P Sbjct: 150 ANERGTASAIFNSAQYAATVIFAPLMAWLVHAFGWHYVFIVMGVIGIVMALAWKRFMHDP 209 Query: 181 KDHPRINQAELAHIESGGGLVDMDNRKVAAPSTKGRGYIRQLLSNRMLLGVYIGQYCINV 240 KDHPRI +AE+ +IE+GGGLV+MD VA GYI+QLL NRML+GVYI QYCIN Sbjct: 210 KDHPRITRAEIEYIEAGGGLVNMDRAGVAKTEGPDMGYIKQLLRNRMLMGVYIAQYCINA 269 Query: 241 ITYFFLTWFPVYLVQERGMSILKAGFVASIPAVCGFIGGVVGGLISDRLIKRGLSVTWAR 300 +TYFF+TWFPVYLVQ RGMSILKAGFVASIPAVCGF+GG++GGL+SD L++RG S++ AR Sbjct: 270 LTYFFITWFPVYLVQARGMSILKAGFVASIPAVCGFLGGILGGLVSDALLRRGASLSVAR 329 Query: 301 KIPIVGGMLLSMTMILCNYVEAQWMVVGIMALAFFGKGVGALGWAVVADTAPKQIVGLSG 360 K+PIV GMLLSM+M++CNYV+AQ +VV +MAL+FFGKG+GALGWAV +DTAPKQI GLSG Sbjct: 330 KVPIVLGMLLSMSMVICNYVDAQGIVVALMALSFFGKGLGALGWAVNSDTAPKQIAGLSG 389 Query: 361 GLFNMFGNVAGITTPIVIGYIVKETGSFSGALVFVGINALVTVISYLVIVKEIKRVELK 419 L N FGN++ ITTPI IGYIV TGSF+GALV+VGI+ALV + YLV+V EIKRVELK Sbjct: 390 ALMNTFGNLSSITTPIAIGYIVNTTGSFNGALVYVGIHALVACLCYLVMVGEIKRVELK 448 >Z4105 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 450 Score = 590 bits (1521), Expect = e-168, Method: Compositional matrix adjust. Identities = 280/421 (66%), Positives = 342/421 (81%), Gaps = 2/421 (0%) Query: 1 LFVVTTVNYADRATLSIAGSAMKTELSLDPVMMGYIFSAFSWAYVLAQLPGGWLLDRFGS 60 LF+VT+ NY DRATLSIAGS M ++ LDPV MGY+FSAFSWAYV+ Q+PGGWLLDRFGS Sbjct: 25 LFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDRFGS 84 Query: 61 KKIYMWSIALWSVFTFLQAGVTWMSTAAAVASLFLLRFMVGLAEAPSFPANGRIVAAWFP 120 K++Y WSI +WS+FT LQ V S + +LF LRF+VGLAEAPSFP N RIVAAWFP Sbjct: 85 KRVYFWSIFIWSMFTLLQGFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWFP 144 Query: 121 TKERGTASAIFNSAQYFAAVLFTPLMAWIVHTYSWHHVFTVMGVVGIALALIWGRIIYSP 180 +ERGTA +IFNSAQYFA V+F P+M W+ H W HVF MG +GIA++ IW ++I+ P Sbjct: 145 AQERGTAVSIFNSAQYFATVIFAPIMGWLTHEVGWSHVFFFMGGLGIAISFIWLKVIHEP 204 Query: 181 KDHPRINQAELAHIESGGGLVDMD--NRKVAAPSTKGRGYIRQLLSNRMLLGVYIGQYCI 238 HP +NQ EL +I +GG L++MD N KV P + G I+QLL +RM++GVYIGQYCI Sbjct: 205 NQHPGVNQKELEYIAAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMIGVYIGQYCI 264 Query: 239 NVITYFFLTWFPVYLVQERGMSILKAGFVASIPAVCGFIGGVVGGLISDRLIKRGLSVTW 298 N +TYFF+TWFPVYLVQ RGMSILKAGFVAS+PAVCGFIGGV+GG+ISD L++R S+ Sbjct: 265 NALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRTGSLNI 324 Query: 299 ARKIPIVGGMLLSMTMILCNYVEAQWMVVGIMALAFFGKGVGALGWAVVADTAPKQIVGL 358 ARK PIV GMLLSM M+ CNYV +WM++G MALAFFGKG+GALGWAV+ADTAPK+I GL Sbjct: 325 ARKTPIVMGMLLSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMADTAPKEISGL 384 Query: 359 SGGLFNMFGNVAGITTPIVIGYIVKETGSFSGALVFVGINALVTVISYLVIVKEIKRVEL 418 SGGLFNMFGN++GI TPI IGYIV TGSF+GAL++VG++AL+ V+SYLV+V +IKR+EL Sbjct: 385 SGGLFNMFGNISGIVTPIAIGYIVGTTGSFNGALIYVGVHALIAVLSYLVLVGDIKRIEL 444 Query: 419 K 419 K Sbjct: 445 K 445 >ECs3649 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 450 Score = 590 bits (1521), Expect = e-168, Method: Compositional matrix adjust. Identities = 280/421 (66%), Positives = 342/421 (81%), Gaps = 2/421 (0%) Query: 1 LFVVTTVNYADRATLSIAGSAMKTELSLDPVMMGYIFSAFSWAYVLAQLPGGWLLDRFGS 60 LF+VT+ NY DRATLSIAGS M ++ LDPV MGY+FSAFSWAYV+ Q+PGGWLLDRFGS Sbjct: 25 LFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDRFGS 84 Query: 61 KKIYMWSIALWSVFTFLQAGVTWMSTAAAVASLFLLRFMVGLAEAPSFPANGRIVAAWFP 120 K++Y WSI +WS+FT LQ V S + +LF LRF+VGLAEAPSFP N RIVAAWFP Sbjct: 85 KRVYFWSIFIWSMFTLLQGFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWFP 144 Query: 121 TKERGTASAIFNSAQYFAAVLFTPLMAWIVHTYSWHHVFTVMGVVGIALALIWGRIIYSP 180 +ERGTA +IFNSAQYFA V+F P+M W+ H W HVF MG +GIA++ IW ++I+ P Sbjct: 145 AQERGTAVSIFNSAQYFATVIFAPIMGWLTHEVGWSHVFFFMGGLGIAISFIWLKVIHEP 204 Query: 181 KDHPRINQAELAHIESGGGLVDMD--NRKVAAPSTKGRGYIRQLLSNRMLLGVYIGQYCI 238 HP +NQ EL +I +GG L++MD N KV P + G I+QLL +RM++GVYIGQYCI Sbjct: 205 NQHPGVNQKELEYIAAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMIGVYIGQYCI 264 Query: 239 NVITYFFLTWFPVYLVQERGMSILKAGFVASIPAVCGFIGGVVGGLISDRLIKRGLSVTW 298 N +TYFF+TWFPVYLVQ RGMSILKAGFVAS+PAVCGFIGGV+GG+ISD L++R S+ Sbjct: 265 NALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRTGSLNI 324 Query: 299 ARKIPIVGGMLLSMTMILCNYVEAQWMVVGIMALAFFGKGVGALGWAVVADTAPKQIVGL 358 ARK PIV GMLLSM M+ CNYV +WM++G MALAFFGKG+GALGWAV+ADTAPK+I GL Sbjct: 325 ARKTPIVMGMLLSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMADTAPKEISGL 384 Query: 359 SGGLFNMFGNVAGITTPIVIGYIVKETGSFSGALVFVGINALVTVISYLVIVKEIKRVEL 418 SGGLFNMFGN++GI TPI IGYIV TGSF+GAL++VG++AL+ V+SYLV+V +IKR+EL Sbjct: 385 SGGLFNMFGNISGIVTPIAIGYIVGTTGSFNGALIYVGVHALIAVLSYLVLVGDIKRIEL 444 Query: 419 K 419 K Sbjct: 445 K 445 >BS_ycbE [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 455 Score = 589 bits (1519), Expect = e-168, Method: Compositional matrix adjust. Identities = 275/420 (65%), Positives = 340/420 (80%) Query: 1 LFVVTTVNYADRATLSIAGSAMKTELSLDPVMMGYIFSAFSWAYVLAQLPGGWLLDRFGS 60 LF+VT++NYADRATLSI G +++ +L LD V MGY+FSAF WAYV+ QLPGGWLLDRFGS Sbjct: 25 LFLVTSINYADRATLSITGDSVQHDLGLDSVAMGYVFSAFGWAYVIGQLPGGWLLDRFGS 84 Query: 61 KKIYMWSIALWSVFTFLQAGVTWMSTAAAVASLFLLRFMVGLAEAPSFPANGRIVAAWFP 120 K I SI WS FT LQ + + S A+ LF LRF+VGL+EAPSFP NGR+VA+WFP Sbjct: 85 KTIIALSIFFWSFFTLLQGAIGFFSAGTAIILLFALRFLVGLSEAPSFPGNGRVVASWFP 144 Query: 121 TKERGTASAIFNSAQYFAAVLFTPLMAWIVHTYSWHHVFTVMGVVGIALALIWGRIIYSP 180 + ERGTASA FNSAQYFA V+F PLM W+ H++ WH VF VMG+ GI LA+IW + +Y P Sbjct: 145 SSERGTASAFFNSAQYFAIVIFPPLMGWLTHSFGWHSVFVVMGIAGILLAVIWLKTVYEP 204 Query: 181 KDHPRINQAELAHIESGGGLVDMDNRKVAAPSTKGRGYIRQLLSNRMLLGVYIGQYCINV 240 K HP++N+AELA+IE GGGL+ MD+ K + YI+QLL+NRML+GVYI QYCI Sbjct: 205 KKHPKVNEAELAYIEQGGGLISMDDSKSKQETESKWPYIKQLLTNRMLIGVYIAQYCITT 264 Query: 241 ITYFFLTWFPVYLVQERGMSILKAGFVASIPAVCGFIGGVVGGLISDRLIKRGLSVTWAR 300 +TYFFLTWFPVYLVQ RGMSIL+AGFVAS+PA+CGF GGV+GG++SD L+K+G S+T+AR Sbjct: 265 LTYFFLTWFPVYLVQARGMSILEAGFVASLPALCGFAGGVLGGIVSDILLKKGRSLTFAR 324 Query: 301 KIPIVGGMLLSMTMILCNYVEAQWMVVGIMALAFFGKGVGALGWAVVADTAPKQIVGLSG 360 K+PI+ GMLLS +MI+CNY ++ W+VV IM+LAFFGKG GALGWAVV+DT+PK+ GLSG Sbjct: 325 KVPIIAGMLLSCSMIVCNYTDSAWLVVVIMSLAFFGKGFGALGWAVVSDTSPKECAGLSG 384 Query: 361 GLFNMFGNVAGITTPIVIGYIVKETGSFSGALVFVGINALVTVISYLVIVKEIKRVELKD 420 GLFN FGN+A ITTPI+IGYIV TGSF+GALVFVG NA+ ++SYL++V IKRV LK Sbjct: 385 GLFNTFGNIASITTPIIIGYIVNATGSFNGALVFVGANAIAAILSYLLLVGPIKRVVLKK 444 >ygcZ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 450 Score = 587 bits (1512), Expect = e-167, Method: Compositional matrix adjust. Identities = 278/421 (66%), Positives = 341/421 (80%), Gaps = 2/421 (0%) Query: 1 LFVVTTVNYADRATLSIAGSAMKTELSLDPVMMGYIFSAFSWAYVLAQLPGGWLLDRFGS 60 LF+VT+ NY DRATLSIAGS M ++ LDPV MGY+FSAFSWAYV+ Q+PGGWLLDRFGS Sbjct: 25 LFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDRFGS 84 Query: 61 KKIYMWSIALWSVFTFLQAGVTWMSTAAAVASLFLLRFMVGLAEAPSFPANGRIVAAWFP 120 K++Y WSI +WS+FT LQ V S + +LF LRF+VGLAEAPSFP N RIVAAWFP Sbjct: 85 KRVYFWSIFIWSMFTLLQGFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWFP 144 Query: 121 TKERGTASAIFNSAQYFAAVLFTPLMAWIVHTYSWHHVFTVMGVVGIALALIWGRIIYSP 180 +ERGTA +IFNSAQYFA V+F P+M W+ H W HVF MG +GI ++ IW ++I+ P Sbjct: 145 AQERGTAVSIFNSAQYFATVIFAPIMGWLTHEVGWSHVFFFMGGLGIVISFIWLKVIHEP 204 Query: 181 KDHPRINQAELAHIESGGGLVDMD--NRKVAAPSTKGRGYIRQLLSNRMLLGVYIGQYCI 238 HP +N+ EL +I +GG L++MD N KV P + G I+QLL +RM++GVYIGQYCI Sbjct: 205 NQHPGVNKKELEYIAAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMIGVYIGQYCI 264 Query: 239 NVITYFFLTWFPVYLVQERGMSILKAGFVASIPAVCGFIGGVVGGLISDRLIKRGLSVTW 298 N +TYFF+TWFPVYLVQ RGMSILKAGFVAS+PAVCGFIGGV+GG+ISD L++R S+ Sbjct: 265 NALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRTGSLNI 324 Query: 299 ARKIPIVGGMLLSMTMILCNYVEAQWMVVGIMALAFFGKGVGALGWAVVADTAPKQIVGL 358 ARK PIV GMLLSM M+ CNYV +WM++G MALAFFGKG+GALGWAV+ADTAPK+I GL Sbjct: 325 ARKTPIVMGMLLSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMADTAPKEISGL 384 Query: 359 SGGLFNMFGNVAGITTPIVIGYIVKETGSFSGALVFVGINALVTVISYLVIVKEIKRVEL 418 SGGLFNMFGN++GI TPI IGYIV TGSF+GAL++VG++AL+ V+SYLV+V +IKR+EL Sbjct: 385 SGGLFNMFGNISGIVTPIAIGYIVGTTGSFNGALIYVGVHALIAVLSYLVLVGDIKRIEL 444 Query: 419 K 419 K Sbjct: 445 K 445