BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0049.0044.p (412 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0805 [GEPR] COG0477 Permeases of the major facilitator superf... 367 e-101 YPO1504 [GEPR] COG0477 Permeases of the major facilitator superf... 177 5e-44 mlr7399 [GEPR] COG0477 Permeases of the major facilitator superf... 159 1e-38 SMb21000 [GEPR] COG0477 Permeases of the major facilitator super... 157 5e-38 PA1412 [GEPR] COG0477 Permeases of the major facilitator superfa... 153 6e-37 >RSc0805 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 409 Score = 367 bits (943), Expect = e-101, Method: Compositional matrix adjust. Identities = 226/394 (57%), Positives = 277/394 (70%), Gaps = 7/394 (1%) Query: 13 PRSPAQRNRLSWKVCLAGMVALSVAMGIGRFAFTPLLPLMLHEGSLNLQMGGWLATANYL 72 P + A R +W+V +AGMVALSVAMGIGRFAFTP+LP+MLH+GS+ L G WLAT NYL Sbjct: 16 PAAHATRTA-AWRVAIAGMVALSVAMGIGRFAFTPILPMMLHDGSVTLGQGSWLATLNYL 74 Query: 73 GYFVGAMACAVHRSKRGVRMLRIGLVATILLTLGMGLLQWNWLWLLMRFLSGVASAYVFV 132 GYFVGA+AC R R++RIGLVAT+LLT GMG+LQ WL++RF +GV SA VFV Sbjct: 75 GYFVGALACMALRGD-AARLIRIGLVATVLLTAGMGVLQGQPAWLVLRFAAGVVSALVFV 133 Query: 133 YTAGWCLHQLTQLQRPELGGVIFCGPGLGIALTGLLTGPMISAGWVAAGGWIAYGIIALG 192 +TAGWCLH+LT+L LGG+IFCGPGLGIA+ GL+ M++ GW A+ WIA+G+++ Sbjct: 134 FTAGWCLHRLTELGHAALGGIIFCGPGLGIAVPGLVASGMVALGWHASSAWIAFGVLSAV 193 Query: 193 LTALVWQTFRFDAGQGQASATTTTPDASAQESPRQKREVTVQVIAYGIAGFGYIITATFL 252 L+A VW T R + + A + P S +P + +AYG+AGFGYI+TATFL Sbjct: 194 LSAAVWPTVRPER---RPHAAASAPGISG-AAPGLGLPTVIITLAYGLAGFGYIVTATFL 249 Query: 253 PVIARQALP-GSAWPDYFWPIFGLSVAAGAFSATRFSVHTDQRLLLTAAYLMQAAGVLLS 311 PVIAR+ LP GS WPD FWPIFG+ VA GA +TR S+ D R LL AAY MQA V S Sbjct: 250 PVIARRVLPAGSIWPDLFWPIFGVGVALGALLSTRISLARDNRTLLAAAYAMQAVAVAAS 309 Query: 312 ILFPNAWGFALSCLLLGLPFTAITLFGMREARRLRREQASSLMALMTAAYGIGQIAGPPL 371 I++P G ALS LLLGLPFTAITLF MREARRL LM LMTA YGIGQIAGPPL Sbjct: 310 IVWPTVGGLALSSLLLGLPFTAITLFAMREARRLWPHAVPRLMGLMTAVYGIGQIAGPPL 369 Query: 372 ATSLVHASGSFTPSLCVAAITLLIGAALYYRLTR 405 A L A+G F SL AA +L++G A++ + R Sbjct: 370 ANRLFAATGGFDASLAAAAASLVLGMAMFLAVRR 403 >YPO1504 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 383 Score = 177 bits (448), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 138/385 (35%), Positives = 190/385 (49%), Gaps = 23/385 (5%) Query: 25 KVCLAGMVALSVAMGIGRFAFTPLLPLMLHEGSLNLQMGGWLATANYLGYFVGAMACAVH 84 +V L+G +AL VAMGIGRFAFTP +PLM+ E L G +A NYLGY GA A+ Sbjct: 4 RVALSGFLALVVAMGIGRFAFTPQVPLMIAEHQFTLTSAGLVAAFNYLGYLFGAFD-AMR 62 Query: 85 RSKRGVRMLRIGLVATILLTLGMGLLQWNWLWLLMRFLSGVASAYVFVYTAGWCLHQLTQ 144 S+ R L +GL LLTL ++ W L+RF G AS + V A W +L Sbjct: 63 ASRHVERRLWLGLWGAALLTLLSAVVVGPWWHGLVRFAIGWASGWSMVLIAAWTNERLAH 122 Query: 145 LQRPELGGVIFCGPGLGIALTGLLTGPMISAGWVAAGGWIAYGIIALGLTALVWQTFRFD 204 RP L +F GPG GI ++G+L + S AA W YG++AL + A + + Sbjct: 123 FGRPALSAAVFAGPGAGIFISGMLAVAIHSYDLSAAEAWWVYGVLALVIIA----SISIN 178 Query: 205 AGQGQASATTTTPDASAQESPRQKREVTVQVIAYGIAGFGYIITATFLPVIARQALPGSA 264 +G +P KR V +Y +AGFGYI+ ATFL +A P S Sbjct: 179 LPRGGELHRPQVVAVPLTLTPALKR----LVWSYSLAGFGYILPATFLSQMASARFPDSL 234 Query: 265 WPDYFWPIFG----LSVAAGAFSATRFSVHTDQRLLLTAAYLMQAAGVLLSILFPNAWGF 320 + + WP+FG + +A G TR + + RL LT +QA GVL + P G Sbjct: 235 FAQFVWPVFGGAAVIGIALGIL--TRHCLTSQTRLALT--LWVQALGVLCAEWVPGVSGL 290 Query: 321 ALSCLLLGLPFTAITLFGMREARRLRREQASSLMALMTAAYGIGQIAGPPL---ATSLVH 377 AL LL G F ++ ++ R L E + L+T Y IGQ+ GP L +T+L H Sbjct: 291 ALGALLTGGGFLSVVQLSLQHGRELAPEHTRYMAGLLTTGYAIGQLVGPILSAISTTLTH 350 Query: 378 ASGSFTPSLCVAAITLLIGAALYYR 402 P+L VA + L+I L + Sbjct: 351 ---RLEPALYVAVVALIIAGGLVIK 372 >mlr7399 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 401 Score = 159 bits (401), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 141/379 (37%), Positives = 200/379 (52%), Gaps = 23/379 (6%) Query: 25 KVCLAGMVALSVAMGIGRFAFTPLLPLMLHEGSLNLQMGGWLATANYLGYFVGAMACAVH 84 + +AGM+A++VAMGIGRF +TP+LP M+ E L+ GW+A+ANYLGY VGA A A Sbjct: 25 RFSVAGMIAMAVAMGIGRFVYTPILPGMMEELHLSPANAGWIASANYLGYLVGAFAAAGG 84 Query: 85 RSKRGVRMLRI-GLVATILLTLGMGLLQWNWLWLLMRFLSGVASAYVFVYTAGWCLHQLT 143 + R+L + GL A+ +L MGL +LL+RFL+G+ASA+V V+ A + Sbjct: 85 WAHGRERLLMLGGLGASTILAALMGLTDAMAAFLLIRFLAGLASAFVMVFMASIVFSHIN 144 Query: 144 QLQRPELGGVIFCGPGLGIALTGLLTGPMIS--AGWVAAGGWI-AYGIIALGLTALVWQT 200 R +L F G GLGIA++ ++ +++ AGW A GW+ + I A G + Sbjct: 145 AAGRGDLQAWHFGGVGLGIAISAVMMAVLVTEHAGW--AAGWLWSAAISACGFVVVALLA 202 Query: 201 FRFDAGQGQASATTTTPDASAQESPRQKREVTVQVIAYGIAGFGYIITATFLPVIARQAL 260 GQA P + R +T +IAYG+ GFGY++TATFL I RQ Sbjct: 203 NEGPLANGQAVREPALP---------KDRSLTKIIIAYGLFGFGYVVTATFLVAIVRQGG 253 Query: 261 PGSAWPDYFWPIFGLSVAAGAFSATRFSVHTDQRLLLTAAY----LMQAAGVLLSILFPN 316 + W + GL+ F +T R+ L AAY L++ GV S+ Sbjct: 254 GSRVFEAMVWLVAGLA----GFPSTWLWQKIAGRVGLNAAYALACLIEVIGVTASVALGG 309 Query: 317 AWGFALSCLLLGLPFTAITLFGMREARRLRREQASSLMALMTAAYGIGQIAGPPLATSLV 376 G L LLLG F AIT G++ AR+ + + ALMTA++G+GQI GP A L Sbjct: 310 YSGPLLGGLLLGGTFIAITALGLQAARQQAPQAPRRIFALMTASFGLGQIIGPIAAGLLA 369 Query: 377 HASGSFTPSLCVAAITLLI 395 SG F + VAA L++ Sbjct: 370 QMSGDFFLASIVAAAMLVV 388 >SMb21000 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 377 Score = 157 bits (397), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 127/388 (32%), Positives = 199/388 (51%), Gaps = 28/388 (7%) Query: 34 LSVAMGIGRFAFTPLLPLMLHEGSLNLQMGGWLATANYLGYFVGAMACA---VHRSKRGV 90 ++VAMG GRF++TP+LP M+ + L+ G +A+AN++GY GA+ H +RGV Sbjct: 1 MAVAMGFGRFSYTPILPAMMTDTGLSPADAGLVASANFIGYLAGAVLAGYRWAHGRERGV 60 Query: 91 RMLRIGLVATILLTLGMGLLQWNWLWLLMRFLSGVASAYVFVYTAGWCLHQLTQLQRPEL 150 + LVAT LL MGL + ++RFL+G+ASA+ ++ +G L Q + + Sbjct: 61 GL--AALVATTLLLAAMGLTSSVLAYSIIRFLAGLASAFAMIFISGIVLGQGLAARSEHV 118 Query: 151 GGVIFCGPGLGIALTGLLT--GPM--ISAGWVAAGGWIAYGIIALGLTALVWQTFRFDAG 206 V F G G GIAL+ + P+ ++ ++ W ++AL T LV Sbjct: 119 PSVHFGGVGFGIALSSIAVWVAPLAGVAGLSMSQADWFVGALVALAGTVLVAALL----- 173 Query: 207 QGQASATTTTPDASAQESP-RQKREVTVQVIAYGIAGFGYIITATFLPVIARQALPGSAW 265 A+ + E P + R + + YG GFGY+ITATFL +AR A G + Sbjct: 174 ----PASRHAANGGRPEVPLVRSRPLMAMTLTYGFFGFGYVITATFLVAMARDASGGHSV 229 Query: 266 PDYFWPIFGLSVAAGAFSATRFSVHTDQRLLLTAAY----LMQAAGVLLSILFPNAWGFA 321 W I G+S A + RF+V R L Y L++A G++L++ P+ + Sbjct: 230 EFLAWLITGVSAALSVY-LWRFAV---PRFGLAGVYAIGLLVEAVGLVLTVSLPSPYAPL 285 Query: 322 LSCLLLGLPFTAITLFGMREARRLRREQASSLMALMTAAYGIGQIAGPPLATSLVHASGS 381 + L+LG F +T +G++ R+L E +A MTAA+GIGQI GP +A L +GS Sbjct: 286 VGGLMLGATFMMVTAYGLQIGRQLAPESPRRALAFMTAAFGIGQIVGPLVAGWLAERTGS 345 Query: 382 FT-PSLCVAAITLLIGAALYYRLTRTHR 408 + P+L A + ++ G + L RT+ Sbjct: 346 YALPTLVAAVVLMICGIVVLAELRRTNE 373 >PA1412 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 397 Score = 153 bits (387), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 135/374 (36%), Positives = 179/374 (47%), Gaps = 14/374 (3%) Query: 38 MGIGRFAFTPLLPLMLHEGSLNLQMGGWLATANYLGYFVGAMACAVHRSKRGVRM-LRIG 96 MG+GRF+ TP LP ++ EG L+L G LA ANYLGY VGA+ R R R+ L +G Sbjct: 24 MGVGRFSLTPQLPHLIREGQLDLTGAGLLAAANYLGYLVGALDALFAREARQARLRLLVG 83 Query: 97 LVATILLTLGMGLLQWNWLWLLMRFLSGVASAYVFVYTAGWCLHQLTQLQRPELGGVIFC 156 L A LTL + W L+RF GVASA+V + + R LG ++F Sbjct: 84 LWACFGLTLASVWAEGFWPHALLRFGLGVASAWVLIMVTALSQRLAAESGRARLGALVFA 143 Query: 157 GPGLGIALTGLLTGPMISAGWVAAGGWIAYGIIALGLTALVWQTFRFDAGQGQASATTTT 216 GPG+G+ +TGLL + G + W + +AL L ++ A +G A Sbjct: 144 GPGIGVMVTGLLAALGNALGQDSVFIWKLFADLALVLILMLLPLLPRPAARG---AGHDA 200 Query: 217 PDASAQESPRQKREVTVQVIAYGIAGFGYIITATFLPVIARQALPGSAWPDYFWPIFGLS 276 P A+A E+ R AYG+ G GYII ATFL +A G D FWP FGL+ Sbjct: 201 P-ATASENAGLGR----LTWAYGLVGLGYIIPATFLSQMAAARFHGQWQADLFWPCFGLA 255 Query: 277 VAAG-AFSATRFSVHTDQRLLLTAAYLMQAAGVLLSILFPNAWGFALSCLLLGLPFTAIT 335 A G + R R L A +QA GV L+ L P G AL +L GLPF A Sbjct: 256 SATGVVLISLRRQRPDGTRRWLVGALWLQALGV-LACLLPGIGGLALGVVLTGLPFLAGM 314 Query: 336 LFGMREARRLRREQASSLMALMTAAYGIGQIAGPPLATSLVHASGSFTPSLCVAAITLLI 395 M+ AR L +T + +GQ+ GP LA H +G P+L +A + L+ Sbjct: 315 QLVMQYARELAPHTPQRNAGQLTTGFALGQLLGPLLAALSTHFAGGLQPALALAGLGLVF 374 Query: 396 GAALYYRLTRTHRL 409 L L R H L Sbjct: 375 AGLL---LRRPHSL 385