BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0049.0008.p (260 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0312 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 354 9e-98 SMc02867 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizob... 325 5e-89 YPO3043 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pe... 313 3e-85 RSc0010 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 311 6e-85 PA2018 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas ... 311 7e-85 >RSp0312 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1049 Score = 354 bits (909), Expect = 9e-98, Method: Compositional matrix adjust. Identities = 206/255 (80%), Positives = 228/255 (89%) Query: 1 MQLEDVMKLYVRNQSGGMVPLAELVKASWREAPTQLQRYQGFPAVRISGSAAPGVASGEA 60 MQ++DV+KLYVRN GGMVPL+E+V+ W E P QL R+QGFPA RISG+AAPG +SG A Sbjct: 774 MQIDDVLKLYVRNAGGGMVPLSEVVRPVWSETPLQLVRFQGFPAARISGNAAPGASSGAA 833 Query: 61 MAEMERLAQQLPPGFAVAWTGQSLQERLSAAQAPMLMALSMLVVFLVLAALYESWSIPLS 120 MAEMERLA QLPPGFA+AWTGQSLQER SAAQAPMLMALSMLVVFLVLAALYESW+IPLS Sbjct: 834 MAEMERLAAQLPPGFAIAWTGQSLQERQSAAQAPMLMALSMLVVFLVLAALYESWAIPLS 893 Query: 121 VMLVVPLGLVGAVAAVILRDMPNDVFFKVGMITVIGLSAKNAILIVEFARQLRSEGMGLV 180 VMLVVPLGL+GAV AV+LR MPNDVFFKVGMITVIGLSAKNAILIVEFA+QLR +G GLV Sbjct: 894 VMLVVPLGLLGAVLAVLLRGMPNDVFFKVGMITVIGLSAKNAILIVEFAKQLREQGKGLV 953 Query: 181 EAAIKASVLRLRPILMTSLAFALGVVPLMLASGASAETQRAIGTGVFGGMVSATVLAVLF 240 E+A+ A+ LRLRPILMTSLAF LGVVPLM+A GASAETQ AIGTGVFGGMVSATVLA+ F Sbjct: 954 ESAVTAARLRLRPILMTSLAFGLGVVPLMIAMGASAETQHAIGTGVFGGMVSATVLAIFF 1013 Query: 241 VPVFFVLVLGCAQRL 255 VPVFFV V+G +R Sbjct: 1014 VPVFFVFVMGLQERF 1028 >SMc02867 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizobium meliloti Length = 1048 Score = 325 bits (834), Expect = 5e-89, Method: Compositional matrix adjust. Identities = 156/238 (65%), Positives = 196/238 (82%) Query: 1 MQLEDVMKLYVRNQSGGMVPLAELVKASWREAPTQLQRYQGFPAVRISGSAAPGVASGEA 60 MQ D++ L VRN +GGMVPL+ W +APTQ Y G+PAVRISG AAPG +SG+A Sbjct: 776 MQTADLLNLNVRNSNGGMVPLSAFADVEWVKAPTQTVGYNGYPAVRISGEAAPGYSSGDA 835 Query: 61 MAEMERLAQQLPPGFAVAWTGQSLQERLSAAQAPMLMALSMLVVFLVLAALYESWSIPLS 120 +AEMERL +LP GF WTGQSLQE S +QAP+L+ALS L+VFL LAALYESWSIP+S Sbjct: 836 IAEMERLVAELPAGFGYEWTGQSLQEIQSGSQAPLLIALSCLLVFLCLAALYESWSIPVS 895 Query: 121 VMLVVPLGLVGAVAAVILRDMPNDVFFKVGMITVIGLSAKNAILIVEFARQLRSEGMGLV 180 V++VVPLG++GAV AV +RDMPNDV+FKVG+I +IGLSAKNAILI+EFA++LR +G L+ Sbjct: 896 VIMVVPLGVIGAVLAVTMRDMPNDVYFKVGLIAIIGLSAKNAILIIEFAKELREQGKSLI 955 Query: 181 EAAIKASVLRLRPILMTSLAFALGVVPLMLASGASAETQRAIGTGVFGGMVSATVLAV 238 ++ ++A+ LR RPILMTSLAF LGV+PL +A+GAS+ +QRAIGTGV GGM+SATVLA+ Sbjct: 956 DSTLEAAHLRFRPILMTSLAFTLGVLPLAIATGASSGSQRAIGTGVMGGMISATVLAI 1013 >YPO3043 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pestis Length = 1043 Score = 313 bits (801), Expect = 3e-85, Method: Compositional matrix adjust. Identities = 152/245 (62%), Positives = 189/245 (77%) Query: 4 EDVMKLYVRNQSGGMVPLAELVKASWREAPTQLQRYQGFPAVRISGSAAPGVASGEAMAE 63 EDV K YVRN++GGMVP + W +L+RY G+ A+ I G AA GV++G AM Sbjct: 782 EDVNKWYVRNKNGGMVPFSAFSTTRWEYGSPRLERYNGYSALEIVGEAASGVSTGTAMDV 841 Query: 64 MERLAQQLPPGFAVAWTGQSLQERLSAAQAPMLMALSMLVVFLVLAALYESWSIPLSVML 123 ME+L QLP GF + WTG S QERLS +QAP L A+S+LVVFL LAALYESWSIP SVML Sbjct: 842 MEKLVSQLPNGFGLEWTGMSYQERLSGSQAPALYAISLLVVFLCLAALYESWSIPFSVML 901 Query: 124 VVPLGLVGAVAAVILRDMPNDVFFKVGMITVIGLSAKNAILIVEFARQLRSEGMGLVEAA 183 VVPLG++GAVAA +R + NDV+F+VG++T+IGLSAKNAILIVEFA +L + G LVEA Sbjct: 902 VVPLGVIGAVAATWMRGLENDVYFQVGLLTIIGLSAKNAILIVEFANELNNRGKDLVEAT 961 Query: 184 IKASVLRLRPILMTSLAFALGVVPLMLASGASAETQRAIGTGVFGGMVSATVLAVLFVPV 243 ++AS RLRPILMTSLAF GV+P+ ++ GA + +Q A+GTGV GGM+SATVLA+ FVP+ Sbjct: 962 LEASRQRLRPILMTSLAFIFGVLPMAISQGAGSGSQHAVGTGVMGGMISATVLAIFFVPL 1021 Query: 244 FFVLV 248 FFVLV Sbjct: 1022 FFVLV 1026 >RSc0010 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1049 Score = 311 bits (798), Expect = 6e-85, Method: Compositional matrix adjust. Identities = 151/237 (63%), Positives = 188/237 (79%) Query: 1 MQLEDVMKLYVRNQSGGMVPLAELVKASWREAPTQLQRYQGFPAVRISGSAAPGVASGEA 60 MQ ED+M LYVRN G MVP++ K W P QL RY G+P+VRISG AA G ++G+A Sbjct: 778 MQPEDIMNLYVRNTQGSMVPMSAFAKGHWVVGPVQLVRYNGYPSVRISGDAATGASTGDA 837 Query: 61 MAEMERLAQQLPPGFAVAWTGQSLQERLSAAQAPMLMALSMLVVFLVLAALYESWSIPLS 120 M EME LA +LP G WTGQSLQE+ S +QAP L ALS+L VFLVLAALYESWSIP + Sbjct: 838 MDEMEHLASRLPAGIGFEWTGQSLQEKSSGSQAPALYALSLLAVFLVLAALYESWSIPAA 897 Query: 121 VMLVVPLGLVGAVAAVILRDMPNDVFFKVGMITVIGLSAKNAILIVEFARQLRSEGMGLV 180 V+LVVPLG++GA+ V LR MP+DV+FKVG+I V+GLSAKNAILI+EFA+ L+++G GL+ Sbjct: 898 VILVVPLGVLGALLGVTLRFMPDDVYFKVGLIAVVGLSAKNAILIIEFAKDLQAQGKGLI 957 Query: 181 EAAIKASVLRLRPILMTSLAFALGVVPLMLASGASAETQRAIGTGVFGGMVSATVLA 237 EA ++A LR RPI+MTS AF LGV+PL +A+GAS+ +QRAIGTGV GGM++ATVLA Sbjct: 958 EATLEAVHLRFRPIIMTSFAFILGVLPLAIATGASSASQRAIGTGVMGGMITATVLA 1014 >PA2018 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas aeruginosa Length = 1045 Score = 311 bits (798), Expect = 7e-85, Method: Compositional matrix adjust. Identities = 158/258 (61%), Positives = 199/258 (77%), Gaps = 1/258 (0%) Query: 3 LEDVMKLYVRNQSGGMVPLAELVKASWREAPTQLQRYQGFPAVRISGSAAPGVASGEAMA 62 ++D+ +L+VRN+ G MVPLA KA+W P QL RY G+P+ + G AAPG +SGEAM Sbjct: 777 IDDIGRLHVRNEQGEMVPLATFAKAAWTLGPPQLTRYNGYPSFNLEGQAAPGYSSGEAMQ 836 Query: 63 EMERLAQQLPPGFAVAWTGQSLQERLSAAQAPMLMALSMLVVFLVLAALYESWSIPLSVM 122 ME+L Q LP G A W+GQS +ERLS AQAP L ALS+L+VFL LAALYESWSIPL+V+ Sbjct: 837 AMEQLMQGLPEGIAHEWSGQSFEERLSGAQAPALFALSVLIVFLALAALYESWSIPLAVI 896 Query: 123 LVVPLGLVGAVAAVILRDMPNDVFFKVGMITVIGLSAKNAILIVEFARQLRSEGMGLVEA 182 LVVPLG++GA+ V LR +PND++FKVG+IT+IGLSAKNAILI+E A+ EGM L++A Sbjct: 897 LVVPLGVLGALLGVSLRGLPNDIYFKVGLITIIGLSAKNAILIIEVAKDHYQEGMSLLQA 956 Query: 183 AIKASVLRLRPILMTSLAFALGVVPLMLASGASAETQRAIGTGVFGGMVSATVLAVLFVP 242 ++A+ LRLRPI+MTSLAF GVVPL L+SGA + Q AIGTGV GG+V+ATVLAV VP Sbjct: 957 TLEAARLRLRPIVMTSLAFGFGVVPLALSSGAGSGAQVAIGTGVLGGIVTATVLAVFLVP 1016 Query: 243 VFFVLVLGCAQRLARKGR 260 +FF LV+G RL + R Sbjct: 1017 LFF-LVVGRLFRLRKAPR 1033