BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0048.0164.p         (210 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SMc01175 [IQR] COG1028 Dehydrogenases with different specificiti...   125   5e-29
VC1119 [IQR] COG1028 Dehydrogenases with different specificities...    92   6e-19
mll0352 [IQR] COG1028 Dehydrogenases with different specificitie...    90   3e-18
FN0216 [IQR] COG1028 Dehydrogenases with different specificities...    84   2e-16
SA1074 [IQR] COG1028 Dehydrogenases with different specificities...    83   5e-16

>SMc01175 [IQR] COG1028 Dehydrogenases with different specificities (related
           to short-chain alcohol dehydrogenases) Sme Sinorhizobium
           meliloti
          Length = 282

 Score =  125 bits (315), Expect = 5e-29,   Method: Compositional matrix adjust.
 Identities = 74/179 (41%), Positives = 100/179 (55%)

Query: 30  ARIVEAFGGVDLLIFCAARYRPERSWEVQEDEAEHTIRTNLASVYSALGAALPDMLARGS 89
           A+I    G V L +  A    P R  +++ +  + +   NL  V + L   +  M  +G 
Sbjct: 79  AKIEYEHGQVALAVLNAGVALPVRGDDLRREPFDRSFAVNLNGVVNCLVPLVEHMKTKGH 138

Query: 90  GGIALVASVAGYVGLPGATVYGPGKAALINLAEILYSDLRPKGVNVYLVNPGFVKTDLTD 149
           G IA+++SVAGY GLP +  YG  KAALIN+AE L  DL   G+ + ++ PGFV T    
Sbjct: 139 GQIAIMSSVAGYGGLPMSAAYGASKAALINMAESLKFDLDRIGIRLQVICPGFVDTQAAP 198

Query: 150 KNDFTMPALQTPQQAASAIWRGIGEGRFEIHFPLRFTAWLKLLRILPFRLRFMLFQRFL 208
           K  F  PAL + Q+AA  I  G+   RFEI FP RFT  +KLLRILP+ L F L  R +
Sbjct: 199 KGGFPRPALVSTQEAADRICAGLKSSRFEITFPKRFTYLVKLLRILPYGLYFALLDRLV 257


>VC1119 [IQR] COG1028 Dehydrogenases with different specificities (related
           to short-chain alcohol dehydrogenases) Vch Vibrio
           cholerae
          Length = 241

 Score = 92.4 bits (228), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 50/117 (42%), Positives = 70/117 (59%)

Query: 92  IALVASVAGYVGLPGATVYGPGKAALINLAEILYSDLRPKGVNVYLVNPGFVKTDLTDKN 151
           +A+V S+A  + LP A  YG  KAA+  LA  L  D RP G+ V  + PGFV T LTD+N
Sbjct: 123 VAIVGSIASELALPRAEAYGASKAAVAYLARTLQLDWRPLGIEVTTIFPGFVATPLTDRN 182

Query: 152 DFTMPALQTPQQAASAIWRGIGEGRFEIHFPLRFTAWLKLLRILPFRLRFMLFQRFL 208
            F MP + T ++AA  I  G+  G  +++FP RFT  ++LL  LP+  +  L +R L
Sbjct: 183 TFAMPMIITVERAAQEIKAGLARGVSQLYFPKRFTWLIRLLGALPYAWQGRLVRRLL 239


>mll0352 [IQR] COG1028 Dehydrogenases with different specificities (related
           to short-chain alcohol dehydrogenases) Mlo Mesorhizobium
           loti
          Length = 273

 Score = 90.1 bits (222), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 60/181 (33%), Positives = 80/181 (44%)

Query: 16  PLDVLCHDAWRDQHARIVEAFGGVDLLIFCAARYRPERSWEVQEDEAEHTIRTNLASVYS 75
           P DV          A I +  G + L +F A  Y       +   +   T   N   + +
Sbjct: 65  PCDVTDEPRMARTVAAIEKELGPIVLAVFNAGNYISTPGEALVVKDFRRTFEVNYFGIIN 124

Query: 76  ALGAALPDMLARGSGGIALVASVAGYVGLPGATVYGPGKAALINLAEILYSDLRPKGVNV 135
            L   +  M  R  G + LV SV  Y G P    YG  KAA+  LAE L  D     + V
Sbjct: 125 GLVPVVEYMRVRSRGHVVLVGSVTAYFGWPTTAAYGGTKAAINILAESLKYDFDKMNIRV 184

Query: 136 YLVNPGFVKTDLTDKNDFTMPALQTPQQAASAIWRGIGEGRFEIHFPLRFTAWLKLLRIL 195
            ++NPGFV T LT+KN   MP L    +A   + + I  G FE+ FP R +  LK L +L
Sbjct: 185 QVINPGFVDTPLTEKNMLPMPGLMPVTRATRRMIKAIKSGGFEVTFPYRTSWPLKFLALL 244

Query: 196 P 196
           P
Sbjct: 245 P 245


>FN0216 [IQR] COG1028 Dehydrogenases with different specificities (related
           to short-chain alcohol dehydrogenases) Fnu Fusobacterium
           nucleatum
          Length = 250

 Score = 84.3 bits (207), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 47/167 (28%), Positives = 85/167 (50%), Gaps = 4/167 (2%)

Query: 37  GGVDLLIFCAARYRPERSWEVQEDEAEHTIRTNLASVYSALGAALPDMLARGSGGIALVA 96
           G +DL+I  A  Y   R+ ++ + EA   I  NL  V +   A    M     G IA+++
Sbjct: 70  GNLDLIINSAGIYTNNRTTKLTDKEAYAMIDINLTGVLNTFEAVRDVMFKNNRGHIAIIS 129

Query: 97  SVAGYVGLPGATVYGPGKAALINLAEILYSDLRPKGVNVYLVNPGFVKTD----LTDKND 152
           SVAG +  P A+VY   K  ++ + E   S  R   +N+  + PG++ TD    L++++ 
Sbjct: 130 SVAGLLDYPKASVYARTKMTIMGVCETYRSFFRNYNINITTIVPGYIATDKLKSLSEEDI 189

Query: 153 FTMPALQTPQQAASAIWRGIGEGRFEIHFPLRFTAWLKLLRILPFRL 199
              P + + +++ + I + I E + +I +PL     + ++R LP +L
Sbjct: 190 TKKPTVLSEEESTNIIIKAIEEKKEKIIYPLSMKILISVIRKLPKKL 236


>SA1074 [IQR] COG1028 Dehydrogenases with different specificities (related
           to short-chain alcohol dehydrogenases) Sau
           Staphylococcus aureus N315
          Length = 246

 Score = 82.8 bits (203), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 49/149 (32%), Positives = 76/149 (51%)

Query: 1   VLEEVAGAHPEAFIAPLDVLCHDAWRDQHARIVEAFGGVDLLIFCAARYRPERSWEVQED 60
           V+EE+     ++F    +V   D  +     +V  FG +D+L+  A   R      ++E 
Sbjct: 45  VVEEIKAKGVDSFAIQANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQ 104

Query: 61  EAEHTIRTNLASVYSALGAALPDMLARGSGGIALVASVAGYVGLPGATVYGPGKAALINL 120
           E +  I TNL  V++ +  A P ML + SG I  ++SV G VG PG   Y   KA +I L
Sbjct: 105 EWDDVIDTNLKGVFNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGL 164

Query: 121 AEILYSDLRPKGVNVYLVNPGFVKTDLTD 149
            +    +L  +G+ V  V PGF+ +D+TD
Sbjct: 165 TKSAARELASRGITVNAVAPGFIVSDMTD 193