BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0048.0122.p (365 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0585 [GEPR] COG0477 Permeases of the major facilitator superf... 270 3e-72 DR2502 [GEPR] COG0477 Permeases of the major facilitator superfa... 169 7e-42 mlr3825 [GEPR] COG0477 Permeases of the major facilitator superf... 152 9e-37 SMc03889 [GEPR] COG0477 Permeases of the major facilitator super... 149 7e-36 BMEI0267 [GEPR] COG0477 Permeases of the major facilitator super... 145 2e-34 >RSc0585 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 408 Score = 270 bits (691), Expect = 3e-72, Method: Compositional matrix adjust. Identities = 182/367 (49%), Positives = 229/367 (62%), Gaps = 8/367 (2%) Query: 1 MAQFFVNGATFATWGVLIPSVKERFALSDAVLSLAMLAVAGGALLTMGQSGKWIARVGSA 60 MA FFVNGAT ATWGV IP+VK RF LS+A LSLAM VA GA+ M +G W ARV + Sbjct: 42 MALFFVNGATIATWGVHIPTVKARFGLSEASLSLAMFMVAAGAIAAMKFAGGWAARVSTR 101 Query: 61 RALRQVGILYAATLRLIPLAPQFWMLVLLLLVFGSAMAAFDVAMSVQAALVEGQRTRPIM 120 RA Q G+++ L+ L P + +L+ LL++FG A A FDVA++ QA VE +PI+ Sbjct: 102 RASVQAGVVFGLMTGLLMLMPSYALLLGLLVLFGIANAGFDVAINAQATTVEAHSHKPII 161 Query: 121 STLHAMFSIGGIAGAALGAV---PGLSPLAHAALVGVVTLAVSLSIGPFALPDEVRDSAA 177 S+LH MFS+GG+ GAA G V G+ H A +G++T ++L GPF LPD V Sbjct: 162 SSLHGMFSLGGMVGAAAGGVLLDLGVPAAVHCAGMGLITAGMALCAGPFMLPDHVHAPGE 221 Query: 178 TPHGADKRARRMVLVLGGIAFLALMCEGGMYDWAAVYMRDVAQSPLAWVSYSYAAFSTGM 237 H R ++ + +AFL L+ EG MYDW VYMR+VAQSP A S YAAFS GM Sbjct: 222 PAHPTTGRTLLVLGL---LAFLGLVGEGAMYDWTTVYMREVAQSPEAQASAGYAAFSGGM 278 Query: 238 AAGRLTGDRIRARIGGLRTLAXRRPHPRSHRRSA--WPSPLATLGGLLLSGLGIANLMPI 295 A R GD RAR G R L A WP P A L G L G+G AN++PI Sbjct: 279 ALARFGGDAARARWGNTRVLGVSGVLATGGILLALLWPDPAAVLAGFALMGVGAANMVPI 338 Query: 296 FFLAAARVPGMAAAESIAAVARFAYVGMLLGPVFIGGVAEHLGLRLSFVGVALVMTVVAL 355 FF+ A+R+PG+ AAE IAAVARFAYVGML+GPVFIG +A H LR VAL M ++A+ Sbjct: 339 FFVTASRMPGVPAAEGIAAVARFAYVGMLIGPVFIGMIAHHSNLRWGLSLVALTMMLIAV 398 Query: 356 FGGKAVR 362 G +A+R Sbjct: 399 AGPRAIR 405 >DR2502 [GEPR] COG0477 Permeases of the major facilitator superfamily Dra Deinococcus radiodurans Length = 471 Score = 169 bits (429), Expect = 7e-42, Method: Compositional matrix adjust. Identities = 147/381 (38%), Positives = 190/381 (49%), Gaps = 36/381 (9%) Query: 2 AQFFVNGATFATWGVLIPSVKERFALSDAVLSLAMLAVAGGALLTMGQSGKWIARVGSAR 61 A F +NGA FATW V IP V+ L++A + A+LAV G+LL+M +G W+AR GS R Sbjct: 98 AVFLINGALFATWAVNIPGVRTALHLTEAQVGAALLAVGLGSLLSMPLTGGWVARWGSGR 157 Query: 62 ALRQVGILYAATLRLIP--LAPQFWMLVLLLLVFGSAMAAFDVAMSVQAALVEGQRTRPI 119 + L L L+P P W L L + G A DVAM+ Q VE RP+ Sbjct: 158 VTALLAPL--TMLSLLPPFFMPSLWWLTAALGLLGVLNGALDVAMNAQGVTVEKALGRPV 215 Query: 120 MSTLHAMFSIGGIAGAALG-AVPGLSP-LAHAALVGVVTLAVSLSIGPFAL------PDE 171 MS LHA FS+GG+ GA LG A+ G P LAH V +++ +L G F L P+ Sbjct: 216 MSRLHAYFSLGGVVGALLGTALVGRVPMLAHVGGVALLSTLTALVAGRFLLADAPTEPET 275 Query: 172 VRDSAATPHGADKRARRMVLVLGGIAFLALMCEGGMYDWAAVYMRDVAQSPLAWVSYSYA 231 + A TP A ++ + FL ++ EG YDWAA+Y RDV P YA Sbjct: 276 AQADAPTPRSGLSPAALLLGG---LCFLGMLSEGAHYDWAALYCRDVLGLPGGQAGVGYA 332 Query: 232 AFSTGMAAGRLTGDRIRARIGGLRTL------AXRRPHPRSHRRSAWPSPLATLGGLLLS 285 AF T M GR GDR RAR G + + + R WP+ L G LS Sbjct: 333 AFVTTMTLGRWFGDRARARFGDVAMVRAGALLSALGLGLALLVREPWPATL----GFALS 388 Query: 286 GLGIANLMPIFFLAAARVPGMAAAESIAAVARFAYVGMLLGPVFIGGVAEHLGLR----L 341 GLG++N++P+ + AA IA VA Y G LLGP IG +A+H GL L Sbjct: 389 GLGLSNVVPVMYGAAGHA---LHGRGIAQVATIGYGGFLLGPPLIGFLAQHSGLPAALGL 445 Query: 342 SFVGVALVMTVVALFGGKAVR 362 + G AL VA GG A R Sbjct: 446 AVAGSAL----VAGLGGVAFR 462 >mlr3825 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 391 Score = 152 bits (385), Expect = 9e-37, Method: Compositional matrix adjust. Identities = 119/366 (32%), Positives = 179/366 (48%), Gaps = 7/366 (1%) Query: 2 AQFFVNGATFATWGVLIPSVKERFALSDAVLSLAMLAVAGGALLTMGQSGKWIARVGSAR 61 A F NG +W IP R +S L L +L GA+ M G I++ GS Sbjct: 19 AIFLANGFLTGSWAPQIPVFLTRLDISKFTLGLLILLFGAGAVTAMTWCGHLISKHGSRT 78 Query: 62 ALRQVGILYAATLRLIPLAPQFWMLVLLLLVFGSAMAAFDVAMSVQAALVEGQRTRPIMS 121 LR G+ + L ++ LAP + + + +FG ++ DVAM+ A +VE + +R IMS Sbjct: 79 VLRWFGLCGSLGLLVVALAPNLPLAAIAMFIFGGSIGGMDVAMNANAVVVERKMSRAIMS 138 Query: 122 TLHAMFS--IGGIAGAALGAVPGLSPLAHAALVGVVTL-AVSLSIGPFALPDEVRDSAAT 178 + H +S G A+ LAHAA+V V+ A+++++G D + AA Sbjct: 139 SSHGFWSLGGFAGGGLGGFAIQHYGHLAHAAVVTVLAFAAIAMAVGYLVAED--KPQAAE 196 Query: 179 PHGADKRARRMVLVLGGIAFLALMCEGGMYDWAAVYMRDVAQSPLAWVSYSYAAFSTGMA 238 H A +V ++G +A L ++ EG + DWAA+Y+R + LA +YAAFS MA Sbjct: 197 HHKFALPANPLVYLIGLMALLTMVSEGAVLDWAALYLRQELGADLAIAGLAYAAFSGVMA 256 Query: 239 AGRLTGDRIRARIGGLRTLAXRRPHPRSHRRSA--WPSPLATLGGLLLSGLGIANLMPIF 296 R GD +R R G + TL + A PSP + G GIAN++PI Sbjct: 257 IMRFFGDGVRNRFGAVTTLRGSAVVAATGMLVAGLSPSPWFAIAAFATCGFGIANMVPII 316 Query: 297 FLAAARVPGMAAAESIAAVARFAYVGMLLGPVFIGGVAEHLGLRLSFVGVALVMTVVALF 356 F A GM++ ++ V Y G+L+ P IG VAEH F+ +++++ VV L Sbjct: 317 FSAGGNQEGMSSGTGMSVVTTMGYSGILVAPSAIGFVAEHSSFGPIFIAMSVLLIVVLLM 376 Query: 357 GGKAVR 362 G A R Sbjct: 377 AGLAHR 382 >SMc03889 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 379 Score = 149 bits (377), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 123/375 (32%), Positives = 186/375 (49%), Gaps = 29/375 (7%) Query: 4 FFVNGATFATWGVLIPSVKERFALSDAVLSLAMLAVAGGALLTMGQSGKWIARVGSARAL 63 F +NG +W IP KER + ++VL L +L G+L+ M +G +IAR+GS + + Sbjct: 12 FLMNGFVTGSWAPKIPEFKERLGIGESVLGLLILGFGIGSLVLMPIAGGFIARLGSQKVV 71 Query: 64 RQVGILYAATLRLIPLAPQFWMLVLLLLVFGSAMAAFDVAMSVQAALVEGQRTRPIMSTL 123 + I+ + L L+ L P W L + + G + A DVAM+ A VE R IMS+ Sbjct: 72 KVTAIILSPLLLLLTLLPNLWTAALGMFLLGGFVGAMDVAMNANAVEVEKSMRRAIMSSC 131 Query: 124 HAMFSIGGIAG--------AALGAVPGLSPLAHAALVGVVTLAVSLSIGPFALPDEVRDS 175 HA +S+GG+ G A G +P HA +V + LA+ P L D Sbjct: 132 HAYWSLGGLIGAGIGGFLMARFGVLP------HAIVVTCLCLAILAVAWPMILADR---- 181 Query: 176 AATPHGADKRAR-RMVL-----VLGGIAFLALMCEGGMYDWAAVYMRDVAQSPLAWVSYS 229 PH A R + R+ + ++G +A +++ EG + DW A+Y++D + + + Sbjct: 182 ---PHPAATREKLRLPMTPLPWLIGIMALFSMVPEGAVLDWGALYLKDELGASVELSGFG 238 Query: 230 YAAFSTGMAAGRLTGDRIRARIGGLRTLAXRRPHPRSHRRSAWPSPLATLG--GLLLSGL 287 +AAFS MAA R GD +R R+G TL + A +P A L G L+G+ Sbjct: 239 FAAFSATMAAMRFAGDHVRDRLGATLTLRICTVTALAGMVLAGLAPNAVLAILGFALAGI 298 Query: 288 GIANLMPIFFLAAARVPGMAAAESIAAVARFAYVGMLLGPVFIGGVAEHLGLRLSFVGVA 347 GI+N++PI F AA +PG+ ++ Y GML P IG +AEH G + F V Sbjct: 299 GISNMVPIAFSAAGNMPGLQPGIGLSVATTMGYSGMLFAPSLIGFIAEHSGFAIIFACVP 358 Query: 348 LVMTVVALFGGKAVR 362 ++ VV L AV Sbjct: 359 VLFIVVLLLSHHAVH 373 >BMEI0267 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 397 Score = 145 bits (365), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 107/354 (30%), Positives = 164/354 (46%), Gaps = 31/354 (8%) Query: 4 FFVNGATFATWGVLIPSVKERFALSDAVLSLAMLAVAGGALLTMGQSGKWIARVGSARAL 63 F +NG F W IP ER L A + L +L G+L M +G A GS + Sbjct: 29 FLMNGYIFGGWAPKIPEFAERLGLDSAGMGLMILVCGLGSLAMMPVAGALSAHRGSGIVV 88 Query: 64 RQVGILYAATLRLIPLAPQFWMLVLLLLVFGSAMAAFDVAMSVQAALVEGQRTRPIMSTL 123 R + + L +I L P V+++L FG MAA DV+M+ A VE + R IMS+ Sbjct: 89 RIFALAFIPALLIITLVPNVVTAVIVMLYFGGTMAAMDVSMNANAVAVEKKMRRAIMSSC 148 Query: 124 HAMFSIGGIAGAALGA--VPGLSPLAHAALVGVVTLAVSLSIGPFALPDEVRDSAATPHG 181 HA +S+GG+ GAA G + + HA + + + + P +PD H Sbjct: 149 HAFWSLGGLIGAATGGFLIAQFGSIVHALVTMIAATILIIVAWPSIIPDTEH------HH 202 Query: 182 ADKRARRMVL-------VLGGIAFLALMCEGGMYDWAAVYMRDVAQSPLAWVSYSYAAFS 234 D +++ L ++G +A +++ EG + DW A +MR + + + +AAFS Sbjct: 203 PDGEKQKLALPRNPLPWLVGVMALFSMVPEGAILDWGAYHMRQDLGASVTVAGFGFAAFS 262 Query: 235 TGMAAGRLTGDRIRARIGGLRTLAXRRPHPRSHRRSAW---------PSPLATLGGLLLS 285 MA R GD +R R G ++TL R+ A S + G + Sbjct: 263 GSMAVMRFAGDLVRDRFGAVKTL-------RACTAIAIIGMLIVGFGNSSATAIIGFAIC 315 Query: 286 GLGIANLMPIFFLAAARVPGMAAAESIAAVARFAYVGMLLGPVFIGGVAEHLGL 339 G+GI+N++PI F A +PG+ + ++ Y GML+ P IG VA H G Sbjct: 316 GIGISNMVPIAFSMAGNMPGVNPSVGLSIATTLGYSGMLVAPSLIGFVARHSGF 369