BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0048.0120.p (277 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGc468 [GER] COG0697 Permeases of the drug/metabolite transporte... 212 8e-55 SMc00381 [GER] COG0697 Permeases of the drug/metabolite transpor... 209 4e-54 RSc0151 [GER] COG0697 Permeases of the drug/metabolite transport... 134 2e-31 BH0396 [GER] COG0697 Permeases of the drug/metabolite transporte... 59 9e-09 SMc01844 [GER] COG0697 Permeases of the drug/metabolite transpor... 59 1e-08 >AGc468 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 287 Score = 212 bits (539), Expect = 8e-55, Method: Compositional matrix adjust. Identities = 129/276 (46%), Positives = 179/276 (64%) Query: 1 MLTAIAPAIWGSTYIVTSQLLPPDRPFTAALIRCLPAGLLLLLMTRRLPARADWWRLLVL 60 ++TA+APAIWG+TY VT++ LP P A++R LPAG+LLLL+ R+LP W R +L Sbjct: 12 LVTALAPAIWGTTYFVTTEFLPQGYPLHVAMLRALPAGILLLLLVRKLPQGIWWPRSFIL 71 Query: 61 SAFNIGLFQALLFVAAYRLPGGLAAVLGAIQPLLVMVLAWAVDGRAPAQITLWAAVAGVA 120 A N F A+LFV+AYRLPGG+AA +GA+QPL+V+ L+ + + A G+A Sbjct: 72 GALNFSFFWAMLFVSAYRLPGGVAATVGAVQPLIVIGLSRLFLSTPVRPLAIGAGFLGIA 131 Query: 121 GMAVLLLSPQTRIEPIGVAAALAGAGCMAAGVWLTRRWQLRLPVLALTGWQLTIGGLMLA 180 G+A+L+L+P ++ IGVAA LAGA MA G LTR+W+ + L T WQLT GG++L Sbjct: 132 GVALLVLTPGAALDGIGVAAGLAGAVSMAFGTVLTRKWRPPVSNLTFTAWQLTAGGILLL 191 Query: 181 PAAWLVDAPLPSLGLTQELAYAYLSLAGALLAYALWFRGIARLPTVAVASLGLLSPLTAV 240 P A+ ++ LP+ + AYL L GA L Y LWFRG+AR+ A ASLG LSP+ A Sbjct: 192 PVAYALEPALPAPTAVNVMGMAYLGLIGAALTYLLWFRGLARIEPSAAASLGFLSPVVAT 251 Query: 241 VLGWVILSQSISGIALAGLVVVLGSVFAVQWSATRR 276 +LGW+ L QS++ +AG + VL S++ Q S R Sbjct: 252 LLGWLALGQSLAPAQIAGFIAVLFSIWLSQRSQLPR 287 >SMc00381 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 290 Score = 209 bits (533), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 129/274 (47%), Positives = 182/274 (66%) Query: 1 MLTAIAPAIWGSTYIVTSQLLPPDRPFTAALIRCLPAGLLLLLMTRRLPARADWWRLLVL 60 +LTAIAPAIWGSTY+VT++ LP P T A++R LPAGLLLLL+ R++P R VL Sbjct: 9 LLTAIAPAIWGSTYLVTTEFLPAGYPVTVAMLRALPAGLLLLLVVRQMPTGVWLARSFVL 68 Query: 61 SAFNIGLFQALLFVAAYRLPGGLAAVLGAIQPLLVMVLAWAVDGRAPAQITLWAAVAGVA 120 A N FQ +LFV+AYRLPGG+AA +GAIQPL+V+VL+ V G +++ A +AG+A Sbjct: 69 GALNFSFFQTMLFVSAYRLPGGVAATVGAIQPLIVIVLSRIVLGSPARALSVVAGIAGMA 128 Query: 121 GMAVLLLSPQTRIEPIGVAAALAGAGCMAAGVWLTRRWQLRLPVLALTGWQLTIGGLMLA 180 G+A+L+L+P+ ++P+GVAA LAGA MA G L+R W + L T WQL GGL+L Sbjct: 129 GVALLVLTPKAALDPVGVAAGLAGAVSMAFGTVLSRHWTPPVSPLTFTAWQLAAGGLLLV 188 Query: 181 PAAWLVDAPLPSLGLTQELAYAYLSLAGALLAYALWFRGIARLPTVAVASLGLLSPLTAV 240 P +L++ LP L + + YL L G Y LWFRG++RL V+ LG LSP+ A+ Sbjct: 189 PVTFLLEPSLPPLTAANIMGFTYLGLIGTAFTYLLWFRGLSRLEPSQVSPLGFLSPVVAI 248 Query: 241 VLGWVILSQSISGIALAGLVVVLGSVFAVQWSAT 274 ++GW +L Q ++ + + G+ V SV+ Q++ T Sbjct: 249 LIGWGVLDQQLTAVQVLGIATVFASVWMSQYAQT 282 >RSc0151 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 309 Score = 134 bits (337), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 121/247 (48%), Positives = 152/247 (61%), Gaps = 1/247 (0%) Query: 3 TAIAPAIWGSTYIVTSQLLPPDRPFTAALIRCLPAGLLLLLMTRRLPARADWWRLLVLSA 62 TA+AP +WG+TYIV +Q LP P +R LPAG+LL+L+ LP R RL ++ Sbjct: 12 TALAPCLWGTTYIVFTQTLPVSHPLLVGALRALPAGILLMLLGPGLPPRDKLGRLALVGL 71 Query: 63 FNIGLFQALLFVAAYRLPGGLAAVLGAIQPLLVMVLAWAVDGRAPAQITLWAAVAGVAGM 122 NIG+F ALLFVAA RLPGG+AA + ++QPLLV +LAW V R P + L AA+AG G+ Sbjct: 72 ANIGVFFALLFVAAARLPGGVAATVMSVQPLLVGLLAWPVLRRRPRPVQLPAALAGSLGV 131 Query: 123 AVLLLSPQTRIEPIGVAAALAGAGCMAAGVWLTRRWQLRLPVLALTGWQLTIGGLMLAPA 182 +L+L P R++ IGVAAAL A MA G L RW LAL WQL +GGL+L P Sbjct: 132 GLLILGPAARLDAIGVAAALGAAASMATGTVLIERWGRVGTPLALAAWQLALGGLVLLPV 191 Query: 183 AWLVDAPLPSLGLTQELAYAYLSLAGALLAYALWFRGIARLPTVAVASLGLLSPLTAVVL 242 A V+ P L +AYL + G L Y LW RGI RL V L LLSPLTA VL Sbjct: 192 ALAVEGLPPVPTLRNAAGFAYLIVIGTALGYWLWVRGIGRL-GADVTFLSLLSPLTATVL 250 Query: 243 GWVILSQ 249 G ++L + Sbjct: 251 GALLLGE 257 >BH0396 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bha Bacillus halodurans Length = 305 Score = 59.3 bits (142), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 67/284 (23%), Positives = 133/284 (46%), Gaps = 21/284 (7%) Query: 9 IWGSTYIVTSQLLPPDRPFTAALIRCLPAGLLLL---LMTRRLPAR-ADWWRLLVLSAFN 64 IWG +++ LL + ++RC ++LL LM R+L R A W L+++ FN Sbjct: 13 IWGFSFVFIEHLLGIVGVWGTVVVRCFAGAIILLPILLMRRKLFYRPAPWKALMIVGIFN 72 Query: 65 IGLFQALLFVAAYRLPGGLAAVLGAIQPLLVMVLAWAVDGRAPAQITLWAAVAGVAGMAV 124 GL L+ ++ + AAVL A+ PL ++ + + A ++ V G +G+ V Sbjct: 73 AGLPWGLIALSQTEIYSSTAAVLNALTPLFTGLIGFLLYSNALSRQQWGGIVLGFSGVVV 132 Query: 125 L------LLSPQTRIEPIGVAAALAGAGCMAAGVWLTRRWQLRLPVLALTGWQLTIGGLM 178 L LL+P+ +GV + C +R V+ +T + L GGL+ Sbjct: 133 LTGFQLQLLAPE---HFVGVGTMILATICYGFASQYVKRHLHDTDVVLITTFSLLFGGLV 189 Query: 179 LAPAAWLVDA-PLPSLGLTQE----LAYAYLSLAGALLAYALWFRGIARLPTVAVASLGL 233 W+ D+ + + LT + ++ L G+ +A+ L++ + + ++ Sbjct: 190 GLIGMWITDSLHVVRVPLTIDWLSLISIIGLGCLGSGMAHLLYYDLMKKGGPEFATTVTY 249 Query: 234 LSPLTAVVLGWVILSQSISGIALAGLVVVLGSVFAVQWSATRRT 277 L P+TA++ G + L + I+ + G++++L V+ +++ +R Sbjct: 250 LIPMTAIIWGKLFLDELITKNIVIGMLMILMGVY---FTSRKRN 290 >SMc01844 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 314 Score = 59.3 bits (142), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 78/259 (30%), Positives = 116/259 (44%), Gaps = 46/259 (17%) Query: 49 PARADWWR-LLVLSAFNIGLFQALLFVAAYRLPGGLAAVLGAIQPL-LVMVLAWAVDGRA 106 PA A WR L++ N + A +F+ + GLAA+L A P+ V++ A + Sbjct: 70 PALAGRWREFLLMGLINNAIPHAFIFLGQTHIGAGLAAILNATTPVWTVLIANVATEDEK 129 Query: 107 PAQITLWAAVAGVAGMAVLLLSPQTRIEPIGVAAALAGAGCMAAGVWLTRRWQLRLPVLA 166 + + G+AG V+L+ P +ALAG A V L W L LPVLA Sbjct: 130 LSTAKFSGCLLGLAG-TVVLIGP----------SALAGLFGTAGDVPL---WALVLPVLA 175 Query: 167 LTGW---------------------QLTIGGLMLAPAAWLVDAP--LPSLGLTQELAYAY 203 + QLT L++ P A LVD P +P LT LA Sbjct: 176 AVSYGFSATYGKRFRDLAPPVTAAGQLTASTLIMLPVAVLVDMPWTMPMPPLTTVLAILG 235 Query: 204 LSLAGALLAYALWFRGIARLPTVAVASLGLLSPLTAVVLGWVILSQ-----SISGIAL-- 256 L+L AY L+FR +A + + LL P +A++LG++ L + + G+ L Sbjct: 236 LALVSTAYAYILFFRIMAEAGATNTSLVTLLVPPSAILLGYLFLGEMLQATDVGGMLLIA 295 Query: 257 AGLVVVLGSVFAVQWSATR 275 AGL ++ G V + +SA R Sbjct: 296 AGLAILDGRVLKLGYSAGR 314