BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0048.0089.p (226 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CC1203 [M] COG0845 Membrane-fusion protein Ccr Caulobacter vibri... 74 2e-13 aq_698 [M] COG0845 Membrane-fusion protein Aae Aquifex aeolicus 72 7e-13 VC0165 [M] COG0845 Membrane-fusion protein Vch Vibrio cholerae 72 9e-13 PA4374 [M] COG0845 Membrane-fusion protein Pae Pseudomonas aerug... 70 3e-12 HI0894 [M] COG0845 Membrane-fusion protein Hin Haemophilus influ... 68 2e-11 >CC1203 [M] COG0845 Membrane-fusion protein Ccr Caulobacter vibrioides Length = 354 Score = 74.3 bits (181), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 56/198 (28%), Positives = 96/198 (48%), Gaps = 5/198 (2%) Query: 3 DKREIRAQLAPVRYTTIAAEIGAVIARLPVTEGARFQRGQTLVQFDCAVQNAQLNKARAS 62 D+ E+ ++ TI + +I + T+G RGQ LV+ ++A + +ARA Sbjct: 39 DRIEVLGAAKGLQSVTITSNTAELITAVRFTDGQAVSRGQVLVELKAEAEDAGIAEARAR 98 Query: 63 LSAADKAWQANKRLAELNSVGRVELDSSEA--EVAKARADMAAQAALVGKCSIAAPFGGR 120 L+ A++ ++ K LA+ R + S A E AKA D A L I APF GR Sbjct: 99 LAQAERDYKRWKTLADQGIAPRATAEQSLAAYETAKAVVDSARANKL--DRVIRAPFAGR 156 Query: 121 VAEQKVREQQFAQPGQTLLEIIDDSALELEFIVPSKWLVWIKPGKVFQIRIDET-GKTYP 179 V V PG ++ + D S + ++F VP ++L ++ G + D G+T+ Sbjct: 157 VGISDVAPGMLISPGTAIVTLDDTSVIRVDFSVPDRYLETLRIGLPINAQPDALPGETFR 216 Query: 180 ARVQRLGARVDPVSQSVK 197 R+ +L R+D ++++K Sbjct: 217 GRIAQLDTRIDTTTRAIK 234 >aq_698 [M] COG0845 Membrane-fusion protein Aae Aquifex aeolicus Length = 374 Score = 72.4 bits (176), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 57/236 (24%), Positives = 104/236 (44%), Gaps = 31/236 (13%) Query: 19 IAAEIGAVIARLPVTEGARFQRGQTLVQFDCAVQNAQLN--------------KARASLS 64 I+ + + + V EG ++GQTL D AQ+N A+A Sbjct: 72 ISTRVMGYVVDVKVKEGDFVKKGQTLFVIDPRDVKAQINIMKQRIAQAQKNYEAAKAHYE 131 Query: 65 AADKAWQANKRLAELNSVGRVELDSSEA--------------EVAKARADMAAQAALVGK 110 A K ++ K+L + ++ + E D EA E+ AR + A + Sbjct: 132 AVKKTYERFKKLLKEGAITQHEFDQVEAQYLAAKAKLQAAKAEIRVAREAYNSAKAQLSY 191 Query: 111 CSIAAPFGGRVAEQKVREQQFAQPGQTLLEIIDDSALELEFIVPSKWLVWIKPGKVFQIR 170 + APF G V ++ V A PG L +++ ++E P K+ I G ++ Sbjct: 192 AEVKAPFDGYVIQKMVDRGDIANPGMPL-AVLETRPYKVEVSFPEKYFGEINIGDTLEVY 250 Query: 171 IDETGKTYPARVQRLGARVDPVSQSVKVVGVVDGKFNELMAGMSGAVMFGQQEQQP 226 +++ G+ +PA+V + VDPVS++ KV ++D N + +G+ V ++ ++P Sbjct: 251 VEKLGRVFPAKVVEVEPAVDPVSRTFKVKALIDD--NNVKSGLFVKVFKLEKIEEP 304 >VC0165 [M] COG0845 Membrane-fusion protein Vch Vibrio cholerae Length = 368 Score = 72.0 bits (175), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 47/167 (28%), Positives = 76/167 (45%) Query: 11 LAPVRYTTIAAEIGAVIARLPVTEGARFQRGQTLVQFDCAVQNAQLNKARASLSAADKAW 70 + P + T+ E VI ++ G + + Q LV D AV+ A L A L AA + Sbjct: 64 IEPNQGVTLTTETAGVIDQITFESGTQVAKDQPLVLLDSAVERANLKSTEARLPAAKAKY 123 Query: 71 QANKRLAELNSVGRVELDSSEAEVAKARADMAAQAALVGKCSIAAPFGGRVAEQKVREQQ 130 + K L S+ + D +EA AD+ + A + + I APF G + + V Q Sbjct: 124 ERYKGLFAKGSISKESYDEAEASYYALSADIESLKATIARREIKAPFAGVIGIRNVFLGQ 183 Query: 131 FAQPGQTLLEIIDDSALELEFIVPSKWLVWIKPGKVFQIRIDETGKT 177 + QPG ++ + D S + L F VP + + I + I +D +T Sbjct: 184 YLQPGTDIVRLEDTSVMRLRFTVPQRDISRISLDQEVDIFVDAYPQT 230 >PA4374 [M] COG0845 Membrane-fusion protein Pae Pseudomonas aeruginosa Length = 376 Score = 70.5 bits (171), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 51/211 (24%), Positives = 100/211 (47%), Gaps = 3/211 (1%) Query: 18 TIAAEIGAVIARLPVTEGARFQRGQTLVQFDCAVQNAQLNKARASLSAADKAWQANKRLA 77 T+ AE+ + + G + + Q L+Q + V+ A L A A L A +Q + L Sbjct: 71 TLTAEVSGTVRDVLFLSGDQVKLDQPLIQLESDVEEATLRTAEADLGLARAEYQRGRELI 130 Query: 78 ELNSVGRVELDSSEAEVAKARADMAAQAALVGKCSIAAPFGGRVAEQKVREQQFAQPGQT 137 ++ + E D A+ AK A +A A + K + APF G + ++V + PG Sbjct: 131 GSKAISKSEFDRLAAQWAKTSATVAELKAALAKKRVLAPFAGTIGIRQVDVGDYVSPGTP 190 Query: 138 LLEIIDDSALELEFIVPSKWLVWIKPGKVFQIRIDET-GKTYPARVQRLGARVDPVSQSV 196 + + D S L L+F +P + + G++ ++R+ + + A + + +VD ++++ Sbjct: 191 IATLQDLSTLLLDFHLPEQDFPLLSRGQLVKVRVAAYPAQVFDAEIAAINPKVDNETRNL 250 Query: 197 KVVGVVDGKFNELMAGMSG--AVMFGQQEQQ 225 +V ++ +L+ GM VM +EQ+ Sbjct: 251 QVRAALENPDGKLLPGMFANLEVMLPGEEQR 281 >HI0894 [M] COG0845 Membrane-fusion protein Hin Haemophilus influenzae Length = 382 Score = 67.8 bits (164), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 48/189 (25%), Positives = 96/189 (50%), Gaps = 2/189 (1%) Query: 27 IARLPVTEGARFQRGQTLVQFDCAVQNAQLNKARASLSAADKAWQANKRLAELNSVGRVE 86 ++++ V G ++G+ LV+ D +V+ A L A+A LSA + +Q L N+V R E Sbjct: 76 VSQVLVQNGQNVKKGEVLVELDSSVERANLQAAQAQLSALRQTYQRYVGLLNSNAVSRQE 135 Query: 87 LDSSEAEVAKARADMAAQAALVGKCSIAAPFGGRVAEQKVREQQFAQPGQTLLEIIDDSA 146 +D+++A A + + A + + I APF G+ K+ Q+ G ++ + D S+ Sbjct: 136 MDNAKAAYDAQVASIESLKAAIERRKIVAPFDGKAGIVKINVGQYVNVGTEIVRVEDTSS 195 Query: 147 LELEFIVPSKWLVWIKPGKVFQIRID-ETGKTYPARVQRLGARVDPVSQSVKVVGVVDGK 205 ++++F + L + G+ D G+T+ AR+ + ++ + V V D + Sbjct: 196 MKVDFALSQNDLDKLHIGQRVTATTDARLGETFSARITAIEPAINSSTGLVDVQATFDPE 255 Query: 206 -FNELMAGM 213 ++L++GM Sbjct: 256 DGHKLLSGM 264