BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0048.0002.p (556 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr2005 [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid... 731 0.0 BMEII0815 [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) ac... 705 0.0 PA2555 [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ... 630 e-180 BH3234 [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ... 336 7e-92 SSO2041 [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid... 315 2e-85 >mlr2005 [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Mlo Mesorhizobium loti Length = 559 Score = 731 bits (1888), Expect = 0.0, Method: Compositional matrix adjust. Identities = 351/544 (64%), Positives = 419/544 (77%) Query: 11 PDYADVYAGFRIETLRKQFQGDFETGINACVECCDRHVEGDNIALDFVSLHGEHQQYSFA 70 P Y D A FRIE + GD TGIN VECC RH + +AL +S GE + +SF Sbjct: 16 PRYEDAVARFRIEDEIARLDGDPLTGINGYVECCGRHTGQNRLALRAISAGGELRLFSFD 75 Query: 71 QVRSMAARVANLLRQQGIQPGQIVAGMLPRTPELLATVLGTLRAGAVYQPLFTAFGPKAI 130 + M+ RV NLL+ G+ PG +VAGMLPR PEL+A +LGT R GA+YQPLFTAFGPKAI Sbjct: 76 DLADMSGRVGNLLKDAGVGPGDVVAGMLPRIPELIALILGTWRIGAIYQPLFTAFGPKAI 135 Query: 131 EHRLALSGASLIVTNVANRDKLDEIANCPQVCTVRESNDPLRAGDIDFRAAVDAQSDDFA 190 EHRL SGA L+VTN ANR KLDE+ CP + T+ DPL AGDIDFRAA+ A S D Sbjct: 136 EHRLGYSGAKLVVTNPANRGKLDEMKTCPPIATILGPGDPLPAGDIDFRAALAAASPDCE 195 Query: 191 PVLRSGADLMLMMSTSGTTGAAKGVPVPLSALQAFSVYMREAVGLLPQDKFWNMADPGWA 250 PV+R G DL +MMSTSGTTG KGVPVPL+AL +F Y+R+A+GL P D FWN+ADPGWA Sbjct: 196 PVMRKGEDLFMMMSTSGTTGLPKGVPVPLNALLSFGAYIRDAIGLRPDDVFWNIADPGWA 255 Query: 251 YGLYYAIIGPLAIGQGITFNEAAFTVSGTYETIRRLGITSLAGAPTAYRMMMAAGEEAAA 310 YGLYYAI GPL +G TFNE AF TY+ I RLG+TSLAG+PTA+R+++A G EAAA Sbjct: 256 YGLYYAITGPLLLGIATTFNEGAFNAGNTYDVIERLGVTSLAGSPTAFRLLLAEGPEAAA 315 Query: 311 SVKGRLRAVSSAGEPLNAEVVRWFASALDVPIHDHYGQTELGMVVNNHHALRHEVVPGSA 370 +KGRLR VSSAGEPLN EV+RWF + L PIHDHYGQTE GM+VNNHH L H V GSA Sbjct: 316 RIKGRLRVVSSAGEPLNPEVIRWFDAHLAAPIHDHYGQTENGMMVNNHHGLAHAVRAGSA 375 Query: 371 GFAMPGYRVVVLDENHQELGANQPGELAIDIARSPLYWFSGYWKQDTPAIAHGYYSTGDN 430 GFAMPGYR+VVLD+ ELG NQPG LA+D+A SPL WF GY + +TPAIA GYY TGD Sbjct: 376 GFAMPGYRMVVLDDEGNELGLNQPGILAVDVANSPLRWFDGYHQAETPAIAGGYYRTGDT 435 Query: 431 VELEPNGSISFIGRSDDVITSAGYRIGPFDVESALLEHPAVADVAVIGLPDPERTEIVKA 490 VE EP+GS+SFIGR+DDVITS+GYRIGPFDVESAL+EHPAV + AV+G+PDP+RTEIVKA Sbjct: 436 VEYEPDGSVSFIGRADDVITSSGYRIGPFDVESALIEHPAVNEAAVVGVPDPQRTEIVKA 495 Query: 491 FVVLSDQFKASDALREQLAQHVKRRLSAHAYPRAIEFLDALPKTPSGKLQRFVLRKMEAD 550 FV+L+ ++ S L E+LAQHV++RLSAHAYPR I+F+ LPKTPSGK+QRF+LR+ E + Sbjct: 496 FVILAPAYQGSTELAEELAQHVRKRLSAHAYPREIDFVAELPKTPSGKIQRFLLRQAEVE 555 Query: 551 RRAG 554 +R G Sbjct: 556 KRKG 559 >BMEII0815 [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Bme Brucella melitensis Length = 568 Score = 705 bits (1819), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/552 (61%), Positives = 414/552 (75%), Gaps = 1/552 (0%) Query: 1 MPELIPAPRQPDYADVYAGFRIETLRKQFQGDFETGINACVECCDRHVEGDNIALDFVSL 60 M E + R Y D A F I G+ +TGINAC+ECCDR+ + +AL +S+ Sbjct: 14 MTESPASARLDRYDDAVAQFDIAKAIALLAGNPDTGINACIECCDRYTGENRVALHAISI 73 Query: 61 HGEHQQYSFAQVRSMAARVANLLRQQGIQPGQIVAGMLPRTPELLATVLGTLRAGAVYQP 120 + +F +R M+ARV N+L GI G +VAG+LPRTPEL+AT+LG R GA+YQP Sbjct: 74 DNTLTELTFEDLRDMSARVGNMLADAGISAGDVVAGLLPRTPELVATILGAWRIGAIYQP 133 Query: 121 LFTAFGPKAIEHRLALSGASLIVTNVANRDKLDEIANCPQVCTVRESNDPLRAGDIDFRA 180 LFTAFGPKAIE R SGA L+VTN+ANR KL E+ NCP+V T+ + L GDIDFRA Sbjct: 134 LFTAFGPKAIEQRFGTSGAKLVVTNLANRSKLAEVENCPRVATILAPGESLPEGDIDFRA 193 Query: 181 AVDAQSDDFAPVLRSGADLMLMMSTSGTTGAAKGVPVPLSALQAFSVYMREAVGLLPQDK 240 AV A S + PV+R G+DL +MMSTSGT G KGVPVPL AL AF YMR+A + Sbjct: 194 AVAAASTECEPVMRKGSDLFMMMSTSGTAGLPKGVPVPLRALMAFGAYMRDAWAA-QRRY 252 Query: 241 FWNMADPGWAYGLYYAIIGPLAIGQGITFNEAAFTVSGTYETIRRLGITSLAGAPTAYRM 300 FWN+ADPGWAYGLYYA+ GPL +G NE FT TY+ I RLG+TSLAG+PTA+R+ Sbjct: 253 FWNIADPGWAYGLYYAVTGPLLLGVPTILNEGGFTAENTYDIIERLGVTSLAGSPTAFRL 312 Query: 301 MMAAGEEAAASVKGRLRAVSSAGEPLNAEVVRWFASALDVPIHDHYGQTELGMVVNNHHA 360 +MAAG E+AA VKGRLR SSAGEPLN EV+RWF + L PIHDHYGQTELGMVVNNHH Sbjct: 313 LMAAGPESAARVKGRLRVASSAGEPLNPEVIRWFDACLGAPIHDHYGQTELGMVVNNHHG 372 Query: 361 LRHEVVPGSAGFAMPGYRVVVLDENHQELGANQPGELAIDIARSPLYWFSGYWKQDTPAI 420 L H V GSAG+AMPGYRV VLDE +E+G N+PG LAIDI SPL WF+GY+K+DTP+I Sbjct: 373 LEHPVRQGSAGYAMPGYRVAVLDEAGKEVGPNEPGVLAIDIDNSPLLWFTGYYKKDTPSI 432 Query: 421 AHGYYSTGDNVELEPNGSISFIGRSDDVITSAGYRIGPFDVESALLEHPAVADVAVIGLP 480 + GYY TGD VE EP+GSISFIGR+DDVITS+GYRIGPFDVESALLEHPAV + AV+G+P Sbjct: 433 SGGYYRTGDTVEFEPHGSISFIGRADDVITSSGYRIGPFDVESALLEHPAVNEAAVVGVP 492 Query: 481 DPERTEIVKAFVVLSDQFKASDALREQLAQHVKRRLSAHAYPRAIEFLDALPKTPSGKLQ 540 DP+RTEIVKAFV+L+ F+ + L E+LA HVK++LSAHAYPR I+F+ LPKTPSGK+Q Sbjct: 493 DPQRTEIVKAFVILAPGFEGTPELAEELALHVKKQLSAHAYPRQIDFVAELPKTPSGKIQ 552 Query: 541 RFVLRKMEADRR 552 RF+LRK E +++ Sbjct: 553 RFLLRKAEVEKQ 564 >PA2555 [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Pae Pseudomonas aeruginosa Length = 555 Score = 630 bits (1625), Expect = e-180, Method: Compositional matrix adjust. Identities = 321/539 (59%), Positives = 392/539 (72%), Gaps = 3/539 (0%) Query: 12 DYADVYAGFRIE-TLRKQFQGDFETGINACVECCDRHVEGDNIALDFVSLHGEHQQYSFA 70 DYA AGF ++ T G + +NACVECCDRH IAL + G Y+F+ Sbjct: 3 DYATTAAGFDLQRTAAATLSGTLQA-LNACVECCDRHALPGRIALFWEGKDGSRASYTFS 61 Query: 71 QVRSMAARVANLLRQQGIQPGQIVAGMLPRTPELLATVLGTLRAGAVYQPLFTAFGPKAI 130 ++++++ R AN L+ QG++PG VAG+LPRTPELL T+LG R GAVYQPLFTAFGPKAI Sbjct: 62 ELKALSGRFANFLQAQGVRPGDCVAGLLPRTPELLVTILGAWRLGAVYQPLFTAFGPKAI 121 Query: 131 EHRLALSGASLIVTNVANRDKLDEIANCPQVCTVR-ESNDPLRAGDIDFRAAVDAQSDDF 189 EHR+A +G+ ++VT+ ANRDKLDE+A+ P TV +R GD F A ++ +F Sbjct: 122 EHRVATAGSKVLVTDAANRDKLDELADPPLAVTVGGPKGQGIRRGDFSFWAELERYPAEF 181 Query: 190 APVLRSGADLMLMMSTSGTTGAAKGVPVPLSALQAFSVYMREAVGLLPQDKFWNMADPGW 249 PV RSG D LMM TSGTTG AK VPVPL A+ AF Y+REAV L P+D FWN+ADPGW Sbjct: 182 EPVPRSGEDPFLMMFTSGTTGLAKPVPVPLKAILAFVGYLREAVDLRPEDAFWNLADPGW 241 Query: 250 AYGLYYAIIGPLAIGQGITFNEAAFTVSGTYETIRRLGITSLAGAPTAYRMMMAAGEEAA 309 AYGLYYA+ GPLA+G TF E F+V T IR GIT+LAG+PTAYR++MAAG A Sbjct: 242 AYGLYYAVAGPLAMGHPTTFYEGPFSVESTCRIIRDYGITNLAGSPTAYRLLMAAGAAAE 301 Query: 310 ASVKGRLRAVSSAGEPLNAEVVRWFASALDVPIHDHYGQTELGMVVNNHHALRHEVVPGS 369 ++KGRLRAVSSAGEPL EV+RWFA L IHDHYGQTELGMV+ NHHAL H V G+ Sbjct: 302 TALKGRLRAVSSAGEPLTPEVIRWFADRLGTTIHDHYGQTELGMVLCNHHALAHPVRVGA 361 Query: 370 AGFAMPGYRVVVLDENHQELGANQPGELAIDIARSPLYWFSGYWKQDTPAIAHGYYSTGD 429 AGFA PG+RVVVLD++ EL QPG LA+D RSPL WF GY +T A YY +GD Sbjct: 362 AGFACPGHRVVVLDDDLNELPPGQPGILALDRRRSPLMWFPGYQGLETAAFVGDYYLSGD 421 Query: 430 NVELEPNGSISFIGRSDDVITSAGYRIGPFDVESALLEHPAVADVAVIGLPDPERTEIVK 489 VEL +GSISF+GR+DDVIT++GYR+GPFDVESAL+EHPAV + AVIG PDPERTE+VK Sbjct: 422 TVELNEDGSISFVGRADDVITTSGYRVGPFDVESALIEHPAVMEAAVIGKPDPERTELVK 481 Query: 490 AFVVLSDQFKASDALREQLAQHVKRRLSAHAYPRAIEFLDALPKTPSGKLQRFVLRKME 548 AFVVL + + L + L ++V++RLSAHAYPR IEFL+ LPKTPSGK+QRF+LR E Sbjct: 482 AFVVLCAGHRPTPELADALQRYVRQRLSAHAYPREIEFLEELPKTPSGKIQRFLLRNQE 540 >BH3234 [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Bha Bacillus halodurans Length = 571 Score = 336 bits (862), Expect = 7e-92, Method: Compositional matrix adjust. Identities = 206/558 (36%), Positives = 298/558 (53%), Gaps = 25/558 (4%) Query: 12 DYADVYAGFRIETLRKQFQGDFETG-INACVECCDRHVEG---DNIALDFVSLHGEHQQY 67 DY + + F ++ KQF +ETG +N E DRH E D +AL + S +QY Sbjct: 17 DYNEAVSTFDWSSVEKQFSW-YETGKVNLAYEAIDRHAESNRQDKVAL-YYSDATRDEQY 74 Query: 68 SFAQVRSMAARVANLLRQQGIQPGQIVAGMLPRTPELLATVLGTLRAGAVYQPLFTAFGP 127 +FA ++ + N+LR G+ G V +PR+PEL +LG ++ GA+ PLF AF Sbjct: 75 TFADMKKYTDKAGNVLRDAGVSKGDRVFIFMPRSPELYFALLGAVKVGAIVGPLFEAFME 134 Query: 128 KAIEHRLALSGASLIVT--NVANRDKLDEIANCPQVCTVR---ESNDPLRAGDIDFRAAV 182 A+ RL S A +++T ++ R +D++ + V V E P R DF + + Sbjct: 135 GAVRDRLEDSEAKVLITTPDLLQRVPVDQLPHLETVFIVGDHVEEEGPYR----DFLSRL 190 Query: 183 DAQSDDFAPVLRSGADLMLMMSTSGTTGAAKGVPVPLSALQAFSVYMREAVGLLPQDKFW 242 SDD D +++ TSG+TG KGV +A+ + + L D +W Sbjct: 191 TQASDDLEIEWVDREDGLILHYTSGSTGKPKGVLHVHNAMIQHYQTGKWVLDLKEDDVYW 250 Query: 243 NMADPGWAYGLYYAIIGPLAIGQGITFNEAAFTVSGTYETIRRLGITSLAGAPTAYRMMM 302 ADPGW G Y I P G F+ + YET+++ T APTA+RM+M Sbjct: 251 CTADPGWVTGTSYGIFAPWLCGATNVIRGGRFSPADWYETLQKYKATVWYSAPTAFRMLM 310 Query: 303 AAGEEAAASVK-GRLRAVSSAGEPLNAEVVRWFASALDVPIHDHYGQTELG-MVVNNHHA 360 +AG+E LR + S GEPLN EVVRW D+ IHD + TE G ++ N+ + Sbjct: 311 SAGDELVKKYDLSSLRHILSVGEPLNPEVVRWGMKVFDLRIHDTWWMTETGAQLICNYPS 370 Query: 361 LRHEVVPGSAGFAMPGYRVVVLDENHQELGANQPGELAIDIARSPLYWFSGYWKQDTPAI 420 + ++ PGS G +PG + ++D+ EL N+ G LAI + WK + Sbjct: 371 M--DIRPGSMGKPLPGIKAAIIDDQGNELPPNRMGNLAIRKGWPSM--MRAIWKNEEKYN 426 Query: 421 AH----GYYSTGDNVELEPNGSISFIGRSDDVITSAGYRIGPFDVESALLEHPAVADVAV 476 ++ G+Y +GD+ ++ +G F GR DDVI ++G R+GPF+VES L+EHPAVA+ V Sbjct: 427 SYFEIDGWYVSGDSAYMDEDGYFWFQGRIDDVIMTSGERVGPFEVESKLVEHPAVAEAGV 486 Query: 477 IGLPDPERTEIVKAFVVLSDQFKASDALREQLAQHVKRRLSAHAYPRAIEFLDALPKTPS 536 IG PDP R EI+KAFV L D ++ +D L+E + VK L+AHA PR IEF D LPKT S Sbjct: 487 IGKPDPVRGEIIKAFVSLRDGYELTDELKEDIRTFVKEGLAAHAAPREIEFKDKLPKTRS 546 Query: 537 GKLQRFVLRKMEADRRAG 554 GK+ R VL+ E D G Sbjct: 547 GKIMRRVLKAWELDLPTG 564 >SSO2041 [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Sso Sulfolobus solfataricus Length = 498 Score = 315 bits (806), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 181/491 (36%), Positives = 267/491 (54%), Gaps = 47/491 (9%) Query: 65 QQYSFAQVRSMAARVANLLRQ-QGIQPGQIVAGMLPRTPELLATVLGTLRAGAVYQPLFT 123 ++ SF+ ++ A R+A L++ I+ G ++A + + + + L TL GA+YQPLFT Sbjct: 45 EEISFSDLKRKALRLALYLKEFHNIKKGDVIAILASKKIQQIIVFLATLSLGAIYQPLFT 104 Query: 124 AFGPKAIEHRLALSGASLIVTNVANRDKLDEIANCPQVCTVRESNDPLRAGDIDFRAAVD 183 AFGP+AI+ R +I +DK+++ + ++ L G++ ++ Sbjct: 105 AFGPEAIKMRTRDVKPKIIFCQDDQKDKIND------AILFSKFDELLSYGELKEIEKIN 158 Query: 184 AQSDDFAPVLRSGADLMLMMSTSGTTGAAKGVPVPLSALQAFSVYMREAVGLLPQDKFWN 243 D ++++ TSGTTG KG + VYM+ +G+ D FWN Sbjct: 159 WD------------DAIILLYTSGTTGTPKGALIAKRLFLNIYVYMKYGIGVRENDVFWN 206 Query: 244 MADPGWAYGLYYAIIGPLAIGQGITFNEAAFTVSGTYETIRRLGITSLAGAPTAYRMMMA 303 ADPGWAYGLYY IIGPL G+ I F + F T E + +T+ A APTAYRM+ Sbjct: 207 PADPGWAYGLYYGIIGPLMFGKTIIFLDEPFNPERTMEFMEENKVTNFAFAPTAYRMI-- 264 Query: 304 AGEEAAASVKGR----LRAVSSAGEPLNAEVVRWFASALDVPIHDHYGQTELGMVVNNHH 359 A +VK + L SSAGEPLN EV+RWF +V I DHYGQTE+GMVV N Sbjct: 265 -----AGTVKKKYDLVLERASSAGEPLNPEVIRWFMDKYNVTIKDHYGQTEVGMVVYNGW 319 Query: 360 ALRHEVVPGSAGFAMPGYRVVVLDENHQELGANQPGELAIDIAR-SPLYWFSGYW---KQ 415 +V GS G PGY V ++++ I + R SP + F GY ++ Sbjct: 320 GYDAKVKIGSMGLPAPGYEVDIIED-------------IIAVKRDSPGFHFLGYLNNPEK 366 Query: 416 DTPAIAHGYYSTGDNVELEPNGSISFIGRSDDVITSAGYRIGPFDVESALLEHPAVADVA 475 + +Y TGDN + G + F+GR DDV+ +GYRIGPF+VES LLE PAV + A Sbjct: 367 TKESFRGDWYLTGDNAYKDEEGYLWFVGRKDDVVKVSGYRIGPFEVESVLLEFPAVLESA 426 Query: 476 VIGLPDPERTEIVKAFVVLSDQFKASDALREQLAQHVKRRLSAHAYPRAIEFLDALPKTP 535 V+ DP R ++ A++VL + S+ L++++ V + S H + ++F+D LPKT Sbjct: 427 VVADEDPIRGHVLHAYIVLKSGYTPSEELKKEIIDFVNTKYSRHVHLERVDFVDKLPKTE 486 Query: 536 SGKLQRFVLRK 546 SGK+QR++LRK Sbjct: 487 SGKIQRYLLRK 497