BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0047.0004.p (309 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_ppsB_2 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 113 4e-25 all2644_1 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 110 4e-24 PA2401 [Q] COG1020 Non-ribosomal peptide synthetase modules and ... 109 7e-24 BS_ppsD_2 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 108 2e-23 all2642 [Q] COG1020 Non-ribosomal peptide synthetase modules and... 108 2e-23 >BS_ppsB_2 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Bsu Bacillus subtilis Length = 1510 Score = 113 bits (283), Expect = 4e-25, Method: Composition-based stats. Identities = 64/190 (33%), Positives = 101/190 (53%), Gaps = 11/190 (5%) Query: 2 TAYAVLLASFAWLLHQRSGAGDFVVGTDVAGRSHPDLERLVGFFVNVLPLRLRPQALAPR 61 T Y +LLA ++ LL + SG D VVG+ AGR H DLER++G FVN L +R +P+ Sbjct: 238 TLYMILLAVYSILLSKLSGQEDIVVGSPAAGRPHADLERVIGMFVNTLAMRSKPEG---H 294 Query: 62 ASFAAWLRHCADVAVNAFDHQEPGFDRIVEAAGVPRERRWNPLVQVLFVLQNTPRAALAL 121 +F+++L +A+ A++HQ+ F+ + + RE NPL + VLQ++ + Sbjct: 295 KTFSSYLHDIRHLALTAYEHQDYPFEELADKLDTNREVNRNPLFDAMLVLQSSEDFRFEV 354 Query: 122 PGVRAELLEPLENWSKFDLALFVEDHAEAGDAEDGPGWRADWVYADALFDAATVAALGRD 181 PG+ + P + SKFDL L E+H G R + Y+ ALF+ T+ Sbjct: 355 PGLSISSVTPKHDISKFDLTLHAEEHLS--------GIRCRFEYSTALFEEETITQWASY 406 Query: 182 WQRLLEQVLA 191 + L++ V A Sbjct: 407 FIELVKGVTA 416 >all2644_1 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Nos Nostoc sp. PCC 7120 Length = 1075 Score = 110 bits (275), Expect = 4e-24, Method: Composition-based stats. Identities = 68/193 (35%), Positives = 99/193 (51%), Gaps = 13/193 (6%) Query: 2 TAYAVLLASFAWLLHQRSGAGDFVVGTDVAGRSHPDLERLVGFFVNVLPLRLRPQALAPR 61 T + LL +F LL++ SG D +VG+ V R P++ L+G FVN L R L+ + Sbjct: 264 TLFMTLLTAFNILLYRYSGQDDILVGSTVTSRDRPEIANLIGLFVNNLIFRTN---LSGK 320 Query: 62 ASFAAWLRHCADVAVNAFDHQEPGFDRIVEAAGVPRERRWNPLVQVLFVLQNTPRAALAL 121 SF L + + A HQ+ F+ +VE R NPL QV+FVL NTP L Sbjct: 321 PSFIELLNQVKETVLGALSHQDLPFEDLVEQLQPERNLSQNPLFQVMFVLHNTPNKTTNL 380 Query: 122 PGVRAELLEPLENWSKFDLALFVEDHAEAGDAEDGP-GWRADWVYADALFDAATVAALGR 180 PG++ E LE + S+FD++L D + P G R W Y+ LF+ AT+ L Sbjct: 381 PGLKIEPLETEHSTSRFDISL---------DMYETPNGLRGTWEYSTELFEQATIERLIA 431 Query: 181 DWQRLLEQVLASP 193 +Q LL ++ +P Sbjct: 432 HFQILLSNIVDNP 444 >PA2401 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Pae Pseudomonas aeruginosa Length = 819 Score = 109 bits (273), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 87/226 (38%), Positives = 116/226 (51%), Gaps = 28/226 (12%) Query: 1 VTAYAVLLASFAWLLHQRSGAGDFVVGTDVAGRSHPDLERLVGFFVNVLPLRLRPQALAP 60 VT + +LLASF LLH+ SG D VG +A R+ + ERL+GFFVN L+ + Sbjct: 258 VTMFMLLLASFQALLHRYSGQADIRVGVPIANRNRVETERLIGFFVNTQVLK---ADING 314 Query: 61 RASFAAWLRHCADVAVNAFDHQEPGFDRIVEAAGVPRERRWNPLVQVLFVLQNTPRAA-- 118 R F L A+ A HQ+ F+++VEA R NPL QV+F Q R+A Sbjct: 315 RMGFDELLAQARQRALEAQAHQDLPFEQLVEALQPERSLGHNPLFQVMFNHQADSRSANQ 374 Query: 119 -LALPGVRAELLEPLENWSKFDLALFVEDHAEAGDAEDGPGWRADWVYADALFDAATVAA 177 + LPG+ E +E + FDL L V +AEDG W A + YA LF+A+TV Sbjct: 375 GVQLPGLSLERMEWRSSSVAFDLTLDVH------EAEDGI-W-ASFGYATDLFEASTVER 426 Query: 178 LGRDWQRLLEQVLASPWTPLDAALPSSPSDTKAEVPSQVLLDEITD 223 L R WQ LL ++A P P+ AE+P +LLDE D Sbjct: 427 LARHWQNLLRGIVAEPGRPV------------AELP--LLLDEERD 458 >BS_ppsD_2 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Bsu Bacillus subtilis Length = 1030 Score = 108 bits (270), Expect = 2e-23, Method: Composition-based stats. Identities = 68/197 (34%), Positives = 102/197 (51%), Gaps = 11/197 (5%) Query: 2 TAYAVLLASFAWLLHQRSGAGDFVVGTDVAGRSHPDLERLVGFFVNVLPLRLRPQALAPR 61 T Y LLA ++ + SG D +G+ +AGR H DLE ++G F N L LR RP A Sbjct: 230 TLYMTLLALYSAFWSRLSGQDDIAIGSPIAGRPHADLEAVLGMFANTLALRTRP---AGN 286 Query: 62 ASFAAWLRHCADVAVNAFDHQEPGFDRIVEAAGVPRERRWNPLVQVLFVLQNTPRAALAL 121 +F +L+ A+ A++HQ+ F+ +V+ GV RE NPL VLQN + L + Sbjct: 287 KTFEEFLKEVRQTALEAYEHQDYPFEELVDKLGVQREMSRNPLFDTTLVLQNMEQQKLKM 346 Query: 122 PGVRAELLEPLENWSKFDLALFVEDHAEAGDAEDGPGWRADWVYADALFDAATVAALGRD 181 V+ + + SKFD++L+V +H D+E + Y+ ALF+ T+ Sbjct: 347 NDVQLQWNDLEHPISKFDISLYVTEH----DSE----LFCQFEYSTALFEKETIQRWASL 398 Query: 182 WQRLLEQVLASPWTPLD 198 + L+E ASP T LD Sbjct: 399 FTTLVEHTAASPETELD 415 >all2642 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Nos Nostoc sp. PCC 7120 Length = 1164 Score = 108 bits (269), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 66/193 (34%), Positives = 100/193 (51%), Gaps = 11/193 (5%) Query: 1 VTAYAVLLASFAWLLHQRSGAGDFVVGTDVAGRSHPDLERLVGFFVNVLPLRLRPQALAP 60 VT + LL ++ LLH+ +G D +VGT VA R ++E L+GFFVN L LR LA Sbjct: 319 VTPFVTLLTAYKILLHRYTGQTDILVGTPVANRHRREIEALIGFFVNTLVLRTN---LAD 375 Query: 61 RASFAAWLRHCADVAVNAFDHQEPGFDRIVEAAGVPRERRWNPLVQVLFVLQNTPRAALA 120 SF L+ + A+DHQ+ F+++VE R+ +NPL QV F L+N P L Sbjct: 376 NPSFQELLQQLINTTWQAYDHQDIPFEKLVEVLQPERDLSFNPLFQVKFRLENAPTEKLE 435 Query: 121 LPGVRAELLEPLENWSKFDLALFVEDHAEAGDAEDGPGWRADWVYADALFDAATVAALGR 180 LPG+ L E +K DL+L + + +E G+ + Y LF T+ + Sbjct: 436 LPGLTLRPLNRTEASAKLDLSLDMYETSE--------GFVGAFEYNRDLFAPETINRMVG 487 Query: 181 DWQRLLEQVLASP 193 +Q +L ++ +P Sbjct: 488 HFQTVLTAIVENP 500