BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0045.0033.p (404 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0078 [GEPR] COG0477 Permeases of the major facilitator superf... 253 4e-67 CAC3482 [GEPR] COG0477 Permeases of the major facilitator superf... 244 4e-64 ECs3543 [GEPR] COG0477 Permeases of the major facilitator superf... 216 6e-56 b2681m [GEPR] COG0477 Permeases of the major facilitator superfa... 216 7e-56 Z3982 [GEPR] COG0477 Permeases of the major facilitator superfam... 216 1e-55 >RSp0078 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 399 Score = 253 bits (647), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 178/391 (45%), Positives = 240/391 (61%), Gaps = 14/391 (3%) Query: 14 AQPGASAHGLSSSLILLLASGAGLAVASLYYSQPMLGVLADDIGASERAVGMVPMSTQLG 73 A P SA + LI LL +GAG++VA +Y + P+LG++ D+ + A+G++P T G Sbjct: 6 ASPTQSATTDTQGLIRLLTAGAGVSVACIYLNHPLLGLIGHDLNIAPHALGVLPTLTAAG 65 Query: 74 YALGILLLAPLGDRYDRRRIILIKAAILTAALLLAG--------AASGVGXGLTATLAQD 125 YA GI PLGDRYDRR +IL KA +LT AL+ + AA+G GL AT+AQD Sbjct: 66 YASGIFFFGPLGDRYDRRVVILWKAVLLTLALIGSCIAPGLPVLAAAGFVIGLAATIAQD 125 Query: 126 IVPAAASLAPEQSRGRVVGTVMTGLLLGILLSRVVSGFVAEHFGWRTMFVAAAASIALIG 185 VP+AA+++ + +R R +GTVMTGLL+GI+ SRV SG VA+HFGWR F +AA+I + Sbjct: 126 FVPSAAAISTDLNRNRNIGTVMTGLLIGIVGSRVFSGIVADHFGWRAAFGVSAAAIVGLA 185 Query: 186 LAAWRGLPRFHPTTHLSYGALMASLATLFKKHGALRRAALAQGLLSVGFSAFWSTLAVML 245 LA P T Y L+ SL TLF +H LR +A Q L+V FS FWST+A+ L Sbjct: 186 LAVRAAHFGVAPATRQPYVTLLRSLGTLFARHPRLRASAFTQAFLAVAFSGFWSTVALHL 245 Query: 246 HGAPFHLGSAAAGAFGLAGAAGALAAPLAGRISDKKGPELVTRLGVGLAIVSFAAMALSP 305 G L + AG GLAGAAGAL A +AGR+S + P + G L +FAAMAL P Sbjct: 246 TGT-IGLSAGQAGLLGLAGAAGALGASIAGRLSGRVAPGHIVAGGALLMAATFAAMALFP 304 Query: 306 WFSTQGQLVLLAVAAVGFDLGVQATLVAHQTIVYSIEPGARSRLNAILFVGMFIGMAAGA 365 L + + + FD+GVQA LV+HQTI+Y++ P ARSR+NA+ MFIGM+AGA Sbjct: 305 H-----SLPAIVIGTLLFDVGVQAALVSHQTIIYALAPEARSRINAVFMTIMFIGMSAGA 359 Query: 366 ALGSLVLAQWGWIAVVALATLAAGLALVVRL 396 SL + W ++A T A+ + L +RL Sbjct: 360 YGASLAWSYAHWTGLMAFCTAASSIGLGLRL 390 >CAC3482 [GEPR] COG0477 Permeases of the major facilitator superfamily Cac Clostridium acetobutylicum Length = 394 Score = 244 bits (622), Expect = 4e-64, Method: Compositional matrix adjust. Identities = 135/367 (36%), Positives = 219/367 (59%), Gaps = 13/367 (3%) Query: 23 LSSSLILLLASGAGLAVASLYYSQPMLGVLADDIGASERAVGMVPMSTQLGYALGILLLA 82 L+ LI++++ GL VA+LYY QP+L ++ SE +VG M TQ+GYA+G++L+ Sbjct: 15 LNKLLIMVMSIACGLTVANLYYIQPLLADISKTFNVSEISVGSAAMLTQIGYAVGMVLIL 74 Query: 83 PLGDRYDRRRII---LIKAAILTAALLLAG-----AASGVGXGLTATLAQDIVPAAASLA 134 PLGD +RR +I L+ + I A++ + S G T+ + Q I+P AA L+ Sbjct: 75 PLGDIKERRNLITTILLFSVISLASMFFSSNIYILTISSFAVGFTSIIPQLIIPLAAQLS 134 Query: 135 PEQSRGRVVGTVMTGLLLGILLSRVVSGFVAEHFGWRTMFVAAAASIALIGLAAWRGLPR 194 ++ RGR++GTVM+GLL+GIL+SR SG + ++GWR +++ AA + + +A + LP Sbjct: 135 NQKDRGRIIGTVMSGLLIGILVSRTFSGILGAYWGWRVVYIIAAIMMIFLMIALRKLLPV 194 Query: 195 FHPTTHLSYGALMASLATLFKKHGALRRAALAQGLLSVGFSAFWSTLAVMLHGAPFHLGS 254 P++++ Y L+ S+ L K LR A++ ++ FSAFW++L +L +++GS Sbjct: 195 SKPSSNVKYIELLKSMFQLIKSEPVLREASINGAMMFAAFSAFWTSLTFLLQSPHYNMGS 254 Query: 255 AAAGAFGLAGAAGALAAPLAGRISDKKGPELVTRLGVGLAIVSFAAMALSPWFSTQGQLV 314 AAG FGL G +GALAAPL GRI+DKKGP + + + + +S+ L + ++ Sbjct: 255 QAAGLFGLVGVSGALAAPLVGRIADKKGPRFIIGICIPIITISYLLFLLLGF-----KIF 309 Query: 315 LLAVAAVGFDLGVQATLVAHQTIVYSIEPGARSRLNAILFVGMFIGMAAGAALGSLVLAQ 374 L + + DLGVQ+ V++QT V+S+ R+R+N + V F+G A G+ +GS Sbjct: 310 GLILGVMLLDLGVQSGNVSNQTRVHSLNEKMRNRINTVYMVSFFLGGAFGSFMGSFTYVH 369 Query: 375 WGWIAVV 381 +GW V Sbjct: 370 FGWYGVC 376 >ECs3543 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 394 Score = 216 bits (551), Expect = 6e-56, Method: Compositional matrix adjust. Identities = 160/395 (40%), Positives = 225/395 (56%), Gaps = 20/395 (5%) Query: 21 HGLSSSLILLLASGAGLAVASLYYSQPMLGVLADDIGASERAVGMVPMSTQLGYALGILL 80 H LS +LI+L++ GLAVAS YY+QP+L +A + S + G + + QLGYA G+L Sbjct: 6 HELSPALIVLMSIATGLAVASNYYAQPLLDTIARNFSLSASSAGFIVTAAQLGYAAGLLF 65 Query: 81 LAPLGDRYDRRRII-----------LIKAAILTAALLLAGAASGVGXGLTATLAQDIVPA 129 L PLGD ++RRR+I LI A+ + A+++ G A GL + +AQ +VP Sbjct: 66 LVPLGDMFERRRLIVSMTLLAAGGMLITASSQSLAMMILGTAL---TGLFSVVAQILVPL 122 Query: 130 AASLAPEQSRGRVVGTVMTGLLLGILLSRVVSGFVAEHFGWRTMFVAAAASIALIGLAAW 189 AA+LA RG+VVGT+M+GLLLGILL+R V+G +A GWRT+F A+ +AL+ LA W Sbjct: 123 AATLASPDKRGKVVGTIMSGLLLGILLARTVAGLLANLGGWRTVFWVASVLMALMALALW 182 Query: 190 RGLPRFHPTTHLSYGALMASLATLFKKHGALRRAALAQGLLSVGFSAFWSTLAVMLHGAP 249 RGLP+ THL+Y L+ S+ ++F + LR AL L FS W+++A +L P Sbjct: 183 RGLPQMKSETHLNYPQLLGSVFSMFISNKILRTRALLGCLTFANFSILWTSMAFLLAAPP 242 Query: 250 FHLGSAAAGAFGLAGAAGALAAPLAGRISDKKGPELVTRLGVGLAIVSFAAMALSPWFST 309 F+ G FGLAGAAGAL A AG +DK T G+ L ++S+ A+ WF Sbjct: 243 FNYSDGVIGLFGLAGAAGALGARPAGGFADKGKSHHTTTFGLLLLLLSWLAI----WFGH 298 Query: 310 QGQLVLLAVAAVGFDLGVQATLVAHQTIVYSIEPGARSRLNAILFVGMFIGMAAGAALGS 369 L L+ + + DL VQ + +QT++Y I P AR+RL A FIG AAG+ + + Sbjct: 299 TSVLALI-IGILVLDLTVQGVHITNQTVIYRIHPDARNRLTAGYMTSYFIGGAAGSLISA 357 Query: 370 LVLAQWGWIAVVALATLAAGLALVVRLWPGAARAR 404 GW A V LA L ++ W G R Sbjct: 358 SAWQHGGW-AGVCLAGATIALVNLLVWWRGFHRQE 391 >b2681m [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 392 Score = 216 bits (551), Expect = 7e-56, Method: Compositional matrix adjust. Identities = 160/393 (40%), Positives = 224/393 (56%), Gaps = 18/393 (4%) Query: 21 HGLSSSLILLLASGAGLAVASLYYSQPMLGVLADDIGASERAVGMVPMSTQLGYALGILL 80 H LS +LI+L++ GLAVAS YY+QP+L +A + S + G + + QLGYA G+L Sbjct: 6 HELSPALIVLMSIATGLAVASNYYAQPLLDTIARNFSLSASSAGFIVTAAQLGYAAGLLF 65 Query: 81 LAPLGDRYDRRRII---------LIKAAILTAALLLAGAASGVGXGLTATLAQDIVPAAA 131 L PLGD ++RRR+I LI A+ + A+++ G A GL + +AQ +VP AA Sbjct: 66 LVPLGDMFERRRLIVSMTLLXXMLITASSQSLAMMILGTAL---TGLFSVVAQILVPLAA 122 Query: 132 SLAPEQSRGRVVGTVMTGLLLGILLSRVVSGFVAEHFGWRTMFVAAAASIALIGLAAWRG 191 +LA RG+VVGT+M+GLLLGILL+R V+G +A GWRT+F A+ +AL+ LA WRG Sbjct: 123 TLASPDKRGKVVGTIMSGLLLGILLARTVAGLLANLGGWRTVFWVASVLMALMALALWRG 182 Query: 192 LPRFHPTTHLSYGALMASLATLFKKHGALRRAALAQGLLSVGFSAFWSTLAVMLHGAPFH 251 LP+ THL+Y L+ S+ ++F LR AL L FS W+++A +L PF+ Sbjct: 183 LPQMKSETHLNYPQLLGSVFSMFISDKILRTRALLGCLTFANFSILWTSMAFLLAAPPFN 242 Query: 252 LGSAAAGAFGLAGAAGALAAPLAGRISDKKGPELVTRLGVGLAIVSFAAMALSPWFSTQG 311 G FGLAGAAGAL A AG +DK T G+ L ++S+ A+ WF Sbjct: 243 YSDGVIGLFGLAGAAGALGARPAGGFADKGKSHHTTTFGLLLLLLSWLAI----WFGHTS 298 Query: 312 QLVLLAVAAVGFDLGVQATLVAHQTIVYSIEPGARSRLNAILFVGMFIGMAAGAALGSLV 371 L L+ + + DL VQ + +QT++Y I P AR+RL A FIG AAG+ + + Sbjct: 299 VLALI-IGILVLDLTVQGVHITNQTVIYRIHPDARNRLTAGYMTSYFIGGAAGSLISASA 357 Query: 372 LAQWGWIAVVALATLAAGLALVVRLWPGAARAR 404 GW A V LA L ++ W G R Sbjct: 358 WQHGGW-AGVCLAGATIALVNLLVWWRGFHRQE 389 >Z3982 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 394 Score = 216 bits (549), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 160/395 (40%), Positives = 225/395 (56%), Gaps = 20/395 (5%) Query: 21 HGLSSSLILLLASGAGLAVASLYYSQPMLGVLADDIGASERAVGMVPMSTQLGYALGILL 80 H LS +LI+L++ GLAVAS YY+QP+L +A + S + G + + QLGYA G+L Sbjct: 6 HELSPALIVLMSIATGLAVASNYYAQPLLDTIARNFSLSASSAGFIVTAAQLGYAAGLLF 65 Query: 81 LAPLGDRYDRRRII-----------LIKAAILTAALLLAGAASGVGXGLTATLAQDIVPA 129 L PLGD ++RRR+I LI A+ + A+++ G A GL + +AQ +VP Sbjct: 66 LVPLGDMFERRRLIVSMTLLAAGGMLITASSQSLAMMILGTAL---TGLFSVVAQILVPL 122 Query: 130 AASLAPEQSRGRVVGTVMTGLLLGILLSRVVSGFVAEHFGWRTMFVAAAASIALIGLAAW 189 AA+LA RG+VVGT+M+GLLLGILL+R V+G +A GWRT+F A+ +AL+ LA W Sbjct: 123 AATLASPDKRGKVVGTIMSGLLLGILLARTVAGLLANLGGWRTVFWVASVLMALMALALW 182 Query: 190 RGLPRFHPTTHLSYGALMASLATLFKKHGALRRAALAQGLLSVGFSAFWSTLAVMLHGAP 249 RGLP+ THL+Y L+ S+ ++F + LR AL L FS W+++A +L P Sbjct: 183 RGLPQMKSETHLNYPQLLGSVFSMFISNKILRTRALLGCLTFANFSIXWTSMAFLLAAPP 242 Query: 250 FHLGSAAAGAFGLAGAAGALAAPLAGRISDKKGPELVTRLGVGLAIVSFAAMALSPWFST 309 F+ G FGLAGAAGAL A AG +DK T G+ L ++S+ A+ WF Sbjct: 243 FNYSDGVIGLFGLAGAAGALGARPAGGFADKGKSHHTTTFGLLLLLLSWLAI----WFGH 298 Query: 310 QGQLVLLAVAAVGFDLGVQATLVAHQTIVYSIEPGARSRLNAILFVGMFIGMAAGAALGS 369 L L+ + + DL VQ + +QT++Y I P AR+RL A FIG AAG+ + + Sbjct: 299 TSVLALI-IGILVLDLTVQGVHITNQTVIYRIHPDARNRLTAGYMTSYFIGGAAGSLISA 357 Query: 370 LVLAQWGWIAVVALATLAAGLALVVRLWPGAARAR 404 GW A V LA L ++ W G R Sbjct: 358 SAWQHGGW-AGVCLAGATIALVNLLVWWRGFHRQE 391