BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0044.0015.p (375 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM3585 [V] COG0842 ABC-type multidrug transport system, permeas... 470 e-132 BMEI0656 [V] COG0842 ABC-type multidrug transport system, permea... 458 e-129 PA5230 [V] COG0842 ABC-type multidrug transport system, permease... 456 e-128 yhhJ [V] COG0842 ABC-type multidrug transport system, permease c... 456 e-128 ZyhhJ [V] COG0842 ABC-type multidrug transport system, permease ... 456 e-128 >STM3585 [V] COG0842 ABC-type multidrug transport system, permease component Sty Salmonella typhimurium LT2 Length = 374 Score = 470 bits (1209), Expect = e-132, Method: Compositional matrix adjust. Identities = 241/369 (65%), Positives = 287/369 (77%) Query: 7 NIYRLGIKELWSLLRDPAMLVLIAYTFSLSIYVAATAMPESLHHAAIAIVDNDGSPLSAR 66 NIY LG+KEL SLL D AML LI + F++S+Y +AT +P SLH A IAI D D S LS R Sbjct: 6 NIYNLGVKELRSLLGDKAMLALIVFAFTISVYSSATVLPGSLHLAPIAIADMDQSQLSNR 65 Query: 67 IAASFYPPHFKVARLVTARQADAGLDDGDYTFVLDIPADFQRDVLAARAPAVQLNVDATR 126 I SFY P F ++TA + DAGLD G YTF ++IP +FQRDVLA R P +Q+NVDATR Sbjct: 66 IVNSFYRPWFLPPEMITATEMDAGLDAGRYTFAVNIPPNFQRDVLAGRQPDIQVNVDATR 125 Query: 127 MSQAFTGNSYIQQMVTNEVAQFVQRQEGGASAPVNLALRMRFNPNLEQSWFGSLMEIINN 186 MSQAFTGNSYIQ +++ EV FV R G PV+L +RMRFNPNL+ +WFG +M IINN Sbjct: 126 MSQAFTGNSYIQNIISGEVNSFVARARGDNVQPVSLEIRMRFNPNLDPAWFGGVMAIINN 185 Query: 187 VTMLSIILTGAALIREREHGTIEHLLVMPVTPAEIMLAKVCSMGVVVALAALASLLLIVR 246 +TML+I+LTG+ALIREREHGT+EHLLVMPVTP EIM+AKV SMG+VV + + SL+L+V+ Sbjct: 186 ITMLAIVLTGSALIREREHGTVEHLLVMPVTPFEIMMAKVWSMGLVVLVVSGLSLMLMVK 245 Query: 247 GALHVPIEGSVALFMLVTCLHLFATTSMGIFMATLARSMPQFGMLTVLVLLPLQLLSGGS 306 G L VPIEGS+ LFML L LFATTS+GIFM T+ARSMPQ G+L +LVLLPLQ+LSGGS Sbjct: 246 GVLGVPIEGSIPLFMLGVALSLFATTSIGIFMGTIARSMPQLGLLMILVLLPLQMLSGGS 305 Query: 307 TPRESMPVLVQDIMLAAPTTHFVAAGQAILYRGAGLEVIWPQLLAIFGIGAVLFMAALGR 366 TPRESMP VQDIML PTTHFV+ QAILYRGAGL ++WPQ L + IG V F+ AL R Sbjct: 306 TPRESMPQAVQDIMLTMPTTHFVSLAQAILYRGAGLSIVWPQFLTLLAIGGVFFLIALLR 365 Query: 367 FRKTISQMA 375 FRKTI MA Sbjct: 366 FRKTIGTMA 374 >BMEI0656 [V] COG0842 ABC-type multidrug transport system, permease component Bme Brucella melitensis Length = 370 Score = 458 bits (1178), Expect = e-129, Method: Compositional matrix adjust. Identities = 229/363 (63%), Positives = 289/363 (79%) Query: 6 ANIYRLGIKELWSLLRDPAMLVLIAYTFSLSIYVAATAMPESLHHAAIAIVDNDGSPLSA 65 ANI+RLGIKEL L+RDP +L+LI Y F+L+IY AA AMPE+L++AAIAIVD D SP+S Sbjct: 4 ANIFRLGIKELRGLMRDPMLLILIVYAFTLAIYTAAKAMPETLNNAAIAIVDEDQSPVSG 63 Query: 66 RIAASFYPPHFKVARLVTARQADAGLDDGDYTFVLDIPADFQRDVLAARAPAVQLNVDAT 125 RI +FYPP+F +L+++ + D +D+G TF L+IP DFQRD+LA RAP +QLNVDAT Sbjct: 64 RITTAFYPPYFVPPKLISSYEMDNRMDEGLDTFALNIPPDFQRDLLAGRAPTIQLNVDAT 123 Query: 126 RMSQAFTGNSYIQQMVTNEVAQFVQRQEGGASAPVNLALRMRFNPNLEQSWFGSLMEIIN 185 RMSQAFTG Y+Q +V EV++F+ G A APV+L LR RFN L + WFG++ +I+ Sbjct: 124 RMSQAFTGGGYVQSIVAGEVSEFLNHYRGSAPAPVDLNLRARFNQELNKGWFGAITNVIS 183 Query: 186 NVTMLSIILTGAALIREREHGTIEHLLVMPVTPAEIMLAKVCSMGVVVALAALASLLLIV 245 +VTMLSIILTGAALIREREHGTIEHLLVMPVTP EIM++KV SMG+VV +A+ +L +V Sbjct: 184 SVTMLSIILTGAALIREREHGTIEHLLVMPVTPIEIMISKVWSMGLVVLVASAFALTFVV 243 Query: 246 RGALHVPIEGSVALFMLVTCLHLFATTSMGIFMATLARSMPQFGMLTVLVLLPLQLLSGG 305 +G L VPI GS+ LF+ L LFATTS+GIF+AT+A SMPQFG+L +L+LLPLQ+LSG Sbjct: 244 QGLLSVPINGSILLFLAGAALQLFATTSLGIFLATVAGSMPQFGLLLMLILLPLQVLSGA 303 Query: 306 STPRESMPVLVQDIMLAAPTTHFVAAGQAILYRGAGLEVIWPQLLAIFGIGAVLFMAALG 365 +TPRESMP ++Q IMLAAP THFV Q+IL+RGAGL V+WPQ LA+F IG+VLF+ AL Sbjct: 304 TTPRESMPEIIQTIMLAAPNTHFVILAQSILFRGAGLGVVWPQFLALFVIGSVLFLFALR 363 Query: 366 RFR 368 RFR Sbjct: 364 RFR 366 >PA5230 [V] COG0842 ABC-type multidrug transport system, permease component Pae Pseudomonas aeruginosa Length = 374 Score = 456 bits (1173), Expect = e-128, Method: Compositional matrix adjust. Identities = 234/373 (62%), Positives = 285/373 (76%) Query: 3 NSWANIYRLGIKELWSLLRDPAMLVLIAYTFSLSIYVAATAMPESLHHAAIAIVDNDGSP 62 S ANI+ LGIKE SL RD AML LI + F+L +Y +AT +PE+LHHA IA+VD D S Sbjct: 2 RSLANIFNLGIKEFRSLGRDYAMLALIVWAFTLGVYSSATGIPETLHHAPIAVVDEDRSQ 61 Query: 63 LSARIAASFYPPHFKVARLVTARQADAGLDDGDYTFVLDIPADFQRDVLAARAPAVQLNV 122 LS+RI +F PP+F+ ++ + D G+D G YTF LDIP DFQRDVLA R P++Q+NV Sbjct: 62 LSSRIVNAFQPPYFRPPEMIGHAEMDRGMDVGLYTFTLDIPPDFQRDVLAGRKPSIQVNV 121 Query: 123 DATRMSQAFTGNSYIQQMVTNEVAQFVQRQEGGASAPVNLALRMRFNPNLEQSWFGSLME 182 DAT+ QAF+G YIQ +V EV +FV R S P + +RM FNPNL Q+WFG +ME Sbjct: 122 DATQTGQAFSGAGYIQNIVATEVREFVSRYRAEPSMPAQIEVRMEFNPNLTQAWFGGVME 181 Query: 183 IINNVTMLSIILTGAALIREREHGTIEHLLVMPVTPAEIMLAKVCSMGVVVALAALASLL 242 +IN +TMLSIILTGAALIREREHGT+EHLLVMP++ EIM+AKV SMG+VV +AA SL Sbjct: 182 VINQITMLSIILTGAALIREREHGTVEHLLVMPLSAFEIMMAKVWSMGLVVLVAAGLSLQ 241 Query: 243 LIVRGALHVPIEGSVALFMLVTCLHLFATTSMGIFMATLARSMPQFGMLTVLVLLPLQLL 302 +VRG L VPI GSV LF+L LHLFATTSMGIF+ T+ARSMPQ G+LT+LVLLPL +L Sbjct: 242 WVVRGWLDVPISGSVGLFLLGAGLHLFATTSMGIFLGTVARSMPQLGLLTILVLLPLNIL 301 Query: 303 SGGSTPRESMPVLVQDIMLAAPTTHFVAAGQAILYRGAGLEVIWPQLLAIFGIGAVLFMA 362 SGG+TPRESMP LVQ+IMLAAPTTHFV+ QAIL+RGAG +++WPQ I IG+ F Sbjct: 302 SGGTTPRESMPELVQNIMLAAPTTHFVSLAQAILFRGAGFDIVWPQFAGIVVIGSAFFFG 361 Query: 363 ALGRFRKTISQMA 375 AL RFR+TISQMA Sbjct: 362 ALWRFRRTISQMA 374 >yhhJ [V] COG0842 ABC-type multidrug transport system, permease component Eco Escherichia coli K12 Length = 375 Score = 456 bits (1172), Expect = e-128, Method: Compositional matrix adjust. Identities = 234/369 (63%), Positives = 282/369 (76%) Query: 7 NIYRLGIKELWSLLRDPAMLVLIAYTFSLSIYVAATAMPESLHHAAIAIVDNDGSPLSAR 66 NI+ LGIKEL SLL D AML LI ++F++S+Y +AT P SL+ A IAI D D S LS R Sbjct: 7 NIFNLGIKELRSLLGDKAMLTLIVFSFTVSVYSSATVTPGSLNLAPIAIADMDQSQLSNR 66 Query: 67 IAASFYPPHFKVARLVTARQADAGLDDGDYTFVLDIPADFQRDVLAARAPAVQLNVDATR 126 I SFY P F ++TA + DAGLD G YTF ++IP +FQRDVLA R P +Q+NVDATR Sbjct: 67 IVNSFYRPWFLPPEMITADEMDAGLDAGRYTFAINIPPNFQRDVLAGRQPDIQVNVDATR 126 Query: 127 MSQAFTGNSYIQQMVTNEVAQFVQRQEGGASAPVNLALRMRFNPNLEQSWFGSLMEIINN 186 MSQAFTGN YIQ ++ EV FV R + V+L RMRFNPNL+ +WFG +M IINN Sbjct: 127 MSQAFTGNGYIQNIINGEVNSFVARYRDNSEPLVSLETRMRFNPNLDPAWFGGVMAIINN 186 Query: 187 VTMLSIILTGAALIREREHGTIEHLLVMPVTPAEIMLAKVCSMGVVVALAALASLLLIVR 246 +TML+I+LTG+ALIREREHGT+EHLLVMP+TP EIM+AK+ SMG+VV + + SL+L+V+ Sbjct: 187 ITMLAIVLTGSALIREREHGTVEHLLVMPITPFEIMMAKIWSMGLVVLVVSGLSLVLMVK 246 Query: 247 GALHVPIEGSVALFMLVTCLHLFATTSMGIFMATLARSMPQFGMLTVLVLLPLQLLSGGS 306 G L VPIEGS+ LFML L LFATTS+GIFM T+ARSMPQ G+L +LVLLPLQ+LSGGS Sbjct: 247 GVLGVPIEGSIPLFMLGVALSLFATTSIGIFMGTIARSMPQLGLLVILVLLPLQMLSGGS 306 Query: 307 TPRESMPVLVQDIMLAAPTTHFVAAGQAILYRGAGLEVIWPQLLAIFGIGAVLFMAALGR 366 TPRESMP +VQDIML PTTHFV+ QAILYRGAG E++WPQ L + IG F AL R Sbjct: 307 TPRESMPQMVQDIMLTMPTTHFVSLAQAILYRGAGFEIVWPQFLTLMAIGGAFFTIALLR 366 Query: 367 FRKTISQMA 375 FRKTI MA Sbjct: 367 FRKTIGTMA 375 >ZyhhJ [V] COG0842 ABC-type multidrug transport system, permease component EcZ Escherichia coli O157:H7 EDL933 Length = 375 Score = 456 bits (1172), Expect = e-128, Method: Compositional matrix adjust. Identities = 234/369 (63%), Positives = 282/369 (76%) Query: 7 NIYRLGIKELWSLLRDPAMLVLIAYTFSLSIYVAATAMPESLHHAAIAIVDNDGSPLSAR 66 NI+ LGIKEL SLL D AML LI ++F++S+Y +AT P SL+ A IAI D D S LS R Sbjct: 7 NIFNLGIKELRSLLGDKAMLTLIVFSFTVSVYSSATVTPGSLNLAPIAIADMDQSQLSNR 66 Query: 67 IAASFYPPHFKVARLVTARQADAGLDDGDYTFVLDIPADFQRDVLAARAPAVQLNVDATR 126 I SFY P F ++TA + DAGLD G YTF ++IP +FQRDVLA R P +Q+NVDATR Sbjct: 67 IVNSFYRPWFLPPEMITADEMDAGLDAGRYTFAINIPPNFQRDVLAGRQPDIQVNVDATR 126 Query: 127 MSQAFTGNSYIQQMVTNEVAQFVQRQEGGASAPVNLALRMRFNPNLEQSWFGSLMEIINN 186 MSQAFTGN YIQ ++ EV FV R + V+L RMRFNPNL+ +WFG +M IINN Sbjct: 127 MSQAFTGNGYIQNIINGEVNSFVARYRDNSEPLVSLETRMRFNPNLDPAWFGGVMAIINN 186 Query: 187 VTMLSIILTGAALIREREHGTIEHLLVMPVTPAEIMLAKVCSMGVVVALAALASLLLIVR 246 +TML+I+LTG+ALIREREHGT+EHLLVMP+TP EIM+AK+ SMG+VV + + SL+L+V+ Sbjct: 187 ITMLAIVLTGSALIREREHGTVEHLLVMPITPFEIMMAKIWSMGLVVLVVSGLSLVLMVK 246 Query: 247 GALHVPIEGSVALFMLVTCLHLFATTSMGIFMATLARSMPQFGMLTVLVLLPLQLLSGGS 306 G L VPIEGS+ LFML L LFATTS+GIFM T+ARSMPQ G+L +LVLLPLQ+LSGGS Sbjct: 247 GVLGVPIEGSIPLFMLGVALSLFATTSIGIFMGTIARSMPQLGLLVILVLLPLQMLSGGS 306 Query: 307 TPRESMPVLVQDIMLAAPTTHFVAAGQAILYRGAGLEVIWPQLLAIFGIGAVLFMAALGR 366 TPRESMP +VQDIML PTTHFV+ QAILYRGAG E++WPQ L + IG F AL R Sbjct: 307 TPRESMPQMVQDIMLIMPTTHFVSLAQAILYRGAGFEIVWPQFLTLMAIGGAFFTIALLR 366 Query: 367 FRKTISQMA 375 FRKTI MA Sbjct: 367 FRKTIGTMA 375