BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0044.0008.p (297 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 234 2e-61 RSp1572 [GEPR] COG0477 Permeases of the major facilitator superf... 228 1e-59 YPO2237 [GEPR] COG0477 Permeases of the major facilitator superf... 224 2e-58 BMEII1096 [GEPR] COG0477 Permeases of the major facilitator supe... 201 2e-51 STM1107 [GEPR] COG0477 Permeases of the major facilitator superf... 192 1e-48 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 234 bits (597), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 134/291 (46%), Positives = 195/291 (67%), Gaps = 1/291 (0%) Query: 1 VLYLTYWFPAQRRARVNGLFMTSFAIAGAVGGPIAGLIMSGMEGVGHLANWQWLFILEGI 60 +LYLTYW+PA+RR R FMT+ A++G +GGPI+G + GV LA WQW+F++EGI Sbjct: 144 ILYLTYWYPAERRGRTTTFFMTAVALSGVIGGPISGWALKTFGGVYGLAGWQWMFLIEGI 203 Query: 61 PSILAGFAVLAWLPEKPANAKWLSEAEKNAVTQVLAAENSAPGKHFSFKDACSNYRVWIC 120 PS++ G VLA+L + ++A+WL++ EK +T+ +AAE A + ++ RVW+ Sbjct: 204 PSVVIGLCVLAYLDNRISHARWLTDEEKALLTRNIAAEE-AQKEDAPIAAIMASPRVWLM 262 Query: 121 AAVYFCVVSGNATIAFWAPSIIKEIGVKGNLQIGLISAIPFIAGTLAMIWNGFHSDKTGE 180 + +YF V G ++FW P++IK+ GV L +GL++AIP+ A +AM+ +D+T E Sbjct: 263 SLIYFSFVMGLYGVSFWLPTLIKQTGVADPLSVGLLTAIPYGAAVVAMVLVARSADRTRE 322 Query: 181 RRLHSAIATLIACIGLVATGMTLGNATLALCSLTLAAIGILAAFPVFWSIPGAFLAGTAA 240 RR H AI L IGLV + + N TLA+ +LTL +GIL P+FWS+P AFLAGT A Sbjct: 323 RRWHIAIPALAGAIGLVLSAVWHTNTTLAMAALTLGTMGILTTLPLFWSLPTAFLAGTGA 382 Query: 241 AGGIALINSIGNLAGFVAPYMIGALKTSTGSLSSGLYFVAALELVASFLVV 291 A GIALINS+GNLAGF++PY +G LK +T S SG+Y +AA ++ + L + Sbjct: 383 AAGIALINSLGNLAGFLSPYAVGWLKDTTRSTDSGMYLLAASMVLGALLTL 433 >RSp1572 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 228 bits (581), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 125/275 (45%), Positives = 173/275 (62%), Gaps = 3/275 (1%) Query: 1 VLYLTYWFPAQRRARVNGLFMTSFAIAGAVGGPIAGLIMSGMEGVGHLANWQWLFILEGI 60 + YLT W+P +R AR + + + + G +GGP + IM G G LA WQW+F+ EGI Sbjct: 136 IYYLTQWYPGERMARAMAVVLGAAPLGGVIGGPASTWIMGHFAGAGGLAGWQWMFLAEGI 195 Query: 61 PSILAGFAVLAWLPEKPANAKWLSEAEKNAVTQVLAAENSAPGKHFSFKDACSNYRVWIC 120 PSIL G A +L +KPA+A+WL++A+K + +A +APG+ SF A + ++++ Sbjct: 196 PSILLGIAAYGYLVDKPADARWLTDAQKAVIAGDIA--RAAPGQASSFGKALTEPKLYVL 253 Query: 121 AAVYFCVVSGNATIAFWAPSIIKEIGVKGNLQIGLISAIPFIAGTLAMIWNGFHSDKTGE 180 AA YFC++ G + FW PSI+K G+ QIGL SAIP +A +AM G SD+ GE Sbjct: 254 AAAYFCLICGVYAVGFWLPSILKSAGLSDLFQIGLYSAIPNLAMIVAMYALGRRSDRRGE 313 Query: 181 RRLHSAIATLIACIGLVATGMTLGNATLALCSLTLAAIGILAAFPVFWSIPGAFLAGTAA 240 R LHSAI ++ GL+A + AL S+TLA+ I A++ VFW+IP L GTAA Sbjct: 314 RHLHSAITAVLGA-GLLAWAAYATSFPAALISITLASAAIFASYSVFWAIPQQHLKGTAA 372 Query: 241 AGGIALINSIGNLAGFVAPYMIGALKTSTGSLSSG 275 AGGIALINSIG GF +P +IG K +TGSL +G Sbjct: 373 AGGIALINSIGLFGGFFSPTLIGWTKEATGSLQAG 407 >YPO2237 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 436 Score = 224 bits (570), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 122/290 (42%), Positives = 181/290 (62%), Gaps = 1/290 (0%) Query: 1 VLYLTYWFPAQRRARVNGLFMTSFAIAGAVGGPIAGLIMSGMEGVGHLANWQWLFILEGI 60 +LY++YWFP+ RR RV GLF+ S ++G +G P++G IM G A WQW+FILEGI Sbjct: 138 ILYISYWFPSHRRGRVYGLFVISVPLSGIIGAPLSGWIMQYFNGFQGYAGWQWMFILEGI 197 Query: 61 PSILAGFAVLAWLPEKPANAKWLSEAEKNAVTQVLAAENSAPGKHFSFKDACSNYRVWIC 120 PS+L G ++ L ++ +A WL++ EK+ + Q +A H +DA RVW+ Sbjct: 198 PSVLVGILIIYKLKDRITHATWLTDKEKD-ILQTNIENEAAHYAHSRLRDAFLQPRVWLL 256 Query: 121 AAVYFCVVSGNATIAFWAPSIIKEIGVKGNLQIGLISAIPFIAGTLAMIWNGFHSDKTGE 180 +YFC++SG TI FW P++I++ GVK L IG ++AIP A + MI +D+ E Sbjct: 257 TLIYFCLISGFYTIGFWLPTLIRDSGVKDILSIGFLTAIPSAAAAVTMIVVSRSADRLRE 316 Query: 181 RRLHSAIATLIACIGLVATGMTLGNATLALCSLTLAAIGILAAFPVFWSIPGAFLAGTAA 240 RR H A+ ++ +G++ + N +A+ LT+ A+G L+ P+FWS+P AFL G+AA Sbjct: 317 RRWHLALTAVLGAVGIILSTYFSDNIVVAMVCLTIGAMGALSTIPLFWSLPTAFLGGSAA 376 Query: 241 AGGIALINSIGNLAGFVAPYMIGALKTSTGSLSSGLYFVAALELVASFLV 290 A GIA INS GNL GFVAPYM+G LK T S ++G+ ++ + + LV Sbjct: 377 AAGIAFINSWGNLGGFVAPYMMGYLKDLTQSTTTGMLIISTTLFIGAALV 426 >BMEII1096 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 451 Score = 201 bits (510), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 111/291 (38%), Positives = 169/291 (58%), Gaps = 1/291 (0%) Query: 1 VLYLTYWFPAQRRARVNGLFMTSFAIAGAVGGPIAGLIMSGMEGVGHLANWQWLFILEGI 60 +LYLTYWFP+ RR + LF AG G P++G IM WQW+F+LE I Sbjct: 153 ILYLTYWFPSHRRGNMFALFQAGSPAAGIFGNPLSGWIMDQFHDTAGWQGWQWMFVLEAI 212 Query: 61 PSILAGFAVLAWLPEKPANAKWLSEAEKNAVTQVLAAENSAPGKHFSFKDACSNYRVWIC 120 P+++ G +L +L AKWL+E EK +++ + A++ S N +W+ Sbjct: 213 PAVVLGVVILLYLDNSVKAAKWLTEEEKAIISRDIEADSKGKAASHSLMSLVKNPMLWVM 272 Query: 121 AAVYFCVVSGNATIAFWAPSIIKEIGVKGNLQIGLISAIPFIAGTLAMIWNGFHSDKTGE 180 +YFC V G + W P++I+ GV N+ IGL+ AIPFI +AM+ +D E Sbjct: 273 MLIYFCFVMGQHGLTLWMPTLIRASGVTSNVTIGLLGAIPFICAIIAMVIFSRSADHYRE 332 Query: 181 RRLHSAIATLIACIGLVATGMTLGNATLALCSLTLAAIGILAAFPVFWSIPGAFLAGTAA 240 RR H + L+ +G V + N T+++ L++AA G+LA P+FWS+P A L+G AA Sbjct: 333 RRWHLVVPALLGAVGFVVAA-SATNTTVSIIFLSMAAAGVLACAPLFWSLPTAILSGAAA 391 Query: 241 AGGIALINSIGNLAGFVAPYMIGALKTSTGSLSSGLYFVAALELVASFLVV 291 A GIALINS+ NLAGF++PYM+G ++ +T S G+Y +A ++ + +V+ Sbjct: 392 AAGIALINSVANLAGFISPYMVGIIRDATHSSELGMYVLAGFLILGAAIVL 442 >STM1107 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 458 Score = 192 bits (487), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 113/298 (37%), Positives = 170/298 (57%), Gaps = 16/298 (5%) Query: 1 VLYLTYWFPAQRRARVNGLFMTSFAIAGAVGGPIAGLIMSGMEGVGHLANWQWLFILEGI 60 +LYLTYWFPA RAR N LFM + A+G ++G I+S ++G+ +L WQWLF+LEG Sbjct: 145 LLYLTYWFPAFFRARANALFMIAMPATTALGSIVSGYILS-LDGIFNLHGWQWLFLLEGF 203 Query: 61 PSILAGFAVLAWLPEKPANAKWLSEAEKNAVTQVLAAEN---SAPGKHFSFKDACSNYRV 117 PS+L G V +L + PA AKWL+ +K + +++ ++ P S +A + Sbjct: 204 PSVLLGIMVWFYLDDTPAKAKWLTAEDKKCLQEMMDSDRLTLVQPEGAIS-HNAMQQRSL 262 Query: 118 W---------ICAAVYFCVVSGNATIAFWAPSIIKEIGV-KGNLQIGLISAIPFIAGTLA 167 W + YFC+ + + I+ W P I+K N+ IGL++AIP I L Sbjct: 263 WREVFTPIVLMYTLAYFCLTNTLSAISIWTPQILKSFNEGSSNITIGLLAAIPQICTILG 322 Query: 168 MIWNGFHSDKTGERRLHSAIATLIACIGLVATGMTLGNATLALCSLTLAAIGILAAFPVF 227 MI+ HSDK ER+ H+A+ L A G + T N + L + +A+ G +A +F Sbjct: 323 MIYWSRHSDKHQERKHHTALPFLFAAAGWLLASATDHN-LIQLLGIVMASTGSFSAMAIF 381 Query: 228 WSIPGAFLAGTAAAGGIALINSIGNLAGFVAPYMIGALKTSTGSLSSGLYFVAALELV 285 W+ P ++ A A GIA+IN+ GN+ ++P+MIG LK TGS +SGL+FVA+L +V Sbjct: 382 WTTPDQSISLRARAIGIAVINATGNIGSALSPFMIGWLKDITGSFNSGLWFVASLLVV 439