BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0043.0030.p (186 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA5540 [R] COG0663 Carbonic anhydrases/acetyltransferases, isole... 306 2e-83 XF2095 [R] COG0663 Carbonic anhydrases/acetyltransferases, isole... 293 2e-79 MA1098 [R] COG0663 Carbonic anhydrases/acetyltransferases, isole... 138 5e-33 all0865_1 [R] COG0663 Carbonic anhydrases/acetyltransferases, is... 116 4e-26 MA2536 [R] COG0663 Carbonic anhydrases/acetyltransferases, isole... 101 9e-22 >PA5540 [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily Pae Pseudomonas aeruginosa Length = 186 Score = 306 bits (784), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 146/186 (78%), Positives = 165/186 (88%) Query: 1 MLRRNPSGHRPQVHESAYVDHTAILCGKVIVHENVFIGPYAVIRADEVDEHGEMEPIIIG 60 M+R+NPSG P + ESAYVD TAI+CGKVI+ NVF+GPYAVIRADEVD G M+PI+IG Sbjct: 1 MIRKNPSGDLPVIDESAYVDKTAIICGKVIIQANVFVGPYAVIRADEVDADGGMQPIVIG 60 Query: 61 AHSNIQDGVVIHSKSGAAVTIGERTSIAHRAIVHGPCTVGDDAFIGFNSVLFNCSIGAGC 120 A+SNIQDGVVIHSKSGAAVTIGE +SIAHR+IVHGPC VGD FIGFNSVLFNC +G GC Sbjct: 61 ANSNIQDGVVIHSKSGAAVTIGEHSSIAHRSIVHGPCEVGDRVFIGFNSVLFNCRVGDGC 120 Query: 121 VVRHNAVVDGCDLPPGFYVPSTERIGAKTDLSTIPRVTVAASEFSEDVARTNNELVLGYK 180 VVRHNAVVDGCDLP GFYVPSTERIG +TDL+++PRV+V+ASEFSEDVARTN +LV GYK Sbjct: 121 VVRHNAVVDGCDLPAGFYVPSTERIGPRTDLASMPRVSVSASEFSEDVARTNVDLVRGYK 180 Query: 181 KLQNEF 186 LQNEF Sbjct: 181 SLQNEF 186 >XF2095 [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily Xfa Xylella fastidiosa 9a5c Length = 211 Score = 293 bits (749), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 144/186 (77%), Positives = 159/186 (85%) Query: 1 MLRRNPSGHRPQVHESAYVDHTAILCGKVIVHENVFIGPYAVIRADEVDEHGEMEPIIIG 60 M+R+NP G P VHESA+VD TAILCG VIV VFIGPYAVIRADE G+++PI IG Sbjct: 26 MIRKNPRGDLPDVHESAFVDPTAILCGCVIVEAGVFIGPYAVIRADETTVEGDIKPIRIG 85 Query: 61 AHSNIQDGVVIHSKSGAAVTIGERTSIAHRAIVHGPCTVGDDAFIGFNSVLFNCSIGAGC 120 +NIQDGVVIHSKSGAAVTIG RTSIAHRAIVHGPCT+G+ FIGFNSVLFNC +G GC Sbjct: 86 IGANIQDGVVIHSKSGAAVTIGARTSIAHRAIVHGPCTIGERVFIGFNSVLFNCVVGDGC 145 Query: 121 VVRHNAVVDGCDLPPGFYVPSTERIGAKTDLSTIPRVTVAASEFSEDVARTNNELVLGYK 180 VVRHNAVVDGCDLPPGFYVPSTERIG+ TDL IPRVTVAASEFSEDVA+TNN LV GY+ Sbjct: 146 VVRHNAVVDGCDLPPGFYVPSTERIGSSTDLGRIPRVTVAASEFSEDVAQTNNRLVEGYR 205 Query: 181 KLQNEF 186 +L+NE Sbjct: 206 RLRNEL 211 >MA1098 [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily Mac Methanosarcina acetivorans str.C2A Length = 181 Score = 138 bits (348), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 73/181 (40%), Positives = 107/181 (59%), Gaps = 5/181 (2%) Query: 5 NPSGHRPQVHESAYVDHTAILCGKVIVHENVFIGPYAVIRADEVDEHGEMEPIIIGAHSN 64 NP P+V + A++ TA++ G + + + VF+GP AV+RADE I + + N Sbjct: 5 NPRKQHPRVSKRAWISETAVIIGNISIADYVFVGPNAVLRADE-----PGSSITVQSGCN 59 Query: 65 IQDGVVIHSKSGAAVTIGERTSIAHRAIVHGPCTVGDDAFIGFNSVLFNCSIGAGCVVRH 124 +QD VV+HS S + V +G+ TS+AH IVHGPC +G+ FIGF +V+F+C+IG +V H Sbjct: 60 VQDNVVVHSLSHSDVLVGKNTSLAHSCIVHGPCRIGEGCFIGFGAVVFDCNIGKDTLVLH 119 Query: 125 NAVVDGCDLPPGFYVPSTERIGAKTDLSTIPRVTVAASEFSEDVARTNNELVLGYKKLQN 184 +VV G D+ G VP I + + + +T +EF V R N ELV GY KL+ Sbjct: 120 RSVVRGIDIFSGRIVPDGTVITRQAYANALEPITKEMTEFKRSVVRANIELVEGYMKLRE 179 Query: 185 E 185 E Sbjct: 180 E 180 >all0865_1 [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily Nos Nostoc sp. PCC 7120 Length = 191 Score = 116 bits (290), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 68/177 (38%), Positives = 94/177 (53%), Gaps = 16/177 (9%) Query: 12 QVHESAYVDHTAILCGKVIVHENVFIGPYAVIRADEVDEHGEMEPIIIGAHSNIQDGVVI 71 Q+HESA+V + + G V + NV I P IRADE P IG ++NIQDGVVI Sbjct: 21 QIHESAFVHPFSNIIGDVHIGANVIIAPGTSIRADE------GTPFHIGENTNIQDGVVI 74 Query: 72 HSKSGA----------AVTIGERTSIAHRAIVHGPCTVGDDAFIGFNSVLFNCSIGAGCV 121 H +V +G S+ H A++HGP VGD++FIGF S +FN +GAGC+ Sbjct: 75 HGLEQGRVVGDDNKEYSVWVGSSASLTHMALIHGPAYVGDNSFIGFRSTVFNAKVGAGCI 134 Query: 122 VRHNAVVDGCDLPPGFYVPSTERIGAKTDLSTIPRVTVAASEFSEDVARTNNELVLG 178 V +A++ ++PPG YVPS I + +P V +F+ V N L G Sbjct: 135 VMMHALIKDVEVPPGKYVPSGAIITNQKQADRLPDVQPQDRDFAHHVIGINQALRAG 191 >MA2536 [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily Mac Methanosarcina acetivorans str.C2A Length = 247 Score = 101 bits (251), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 60/197 (30%), Positives = 95/197 (48%), Gaps = 27/197 (13%) Query: 5 NPSGHRPQVHESAYVDHTAILCGKVIVHENVFIGPYAVIRADEVDEHGEMEPIIIGAHSN 64 NP P + +AY+ A + G V + +V + P A +R+DE PI +G +N Sbjct: 56 NPEPTEPVIDSTAYIHPQAAVIGDVTIGASVMVSPMASVRSDE------GTPIFVGDETN 109 Query: 65 IQDGVVIHSKSGA-------------------AVTIGERTSIAHRAIVHGPCTVGDDAFI 105 IQDGVV+H+ AV +GER S+AH++ +HGP VG+D FI Sbjct: 110 IQDGVVLHALETVNEEGEPVESNLVEVDGEKYAVYVGERVSLAHQSQIHGPAYVGNDTFI 169 Query: 106 GFNSVLFNCSIGAGCVVRHNAVVDGCDLPPGFYVPSTERIGAKTDLSTIPRVT--VAASE 163 G +++F ++G CV+ + G +P G Y+P+ + ++ + +P VT Sbjct: 170 GMQALVFKANVGDNCVLEPKSGAIGVTIPDGRYIPAGTVVTSQAEADELPEVTDDYGYKH 229 Query: 164 FSEDVARTNNELVLGYK 180 +E V N L GY Sbjct: 230 TNEAVVYVNVNLAAGYN 246