BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0042.0330.p (374 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2172 [GEPR] COG0477 Permeases of the major facilitator superf... 285 9e-77 PA3573 [GEPR] COG0477 Permeases of the major facilitator superfa... 239 9e-63 CC1230 [GEPR] COG0477 Permeases of the major facilitator superfa... 220 4e-57 PA4136 [GEPR] COG0477 Permeases of the major facilitator superfa... 209 9e-54 PM1533 [GEPR] COG0477 Permeases of the major facilitator superfa... 207 4e-53 >RSc2172 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 407 Score = 285 bits (730), Expect = 9e-77, Method: Compositional matrix adjust. Identities = 140/272 (51%), Positives = 184/272 (67%) Query: 11 GKFPAWLAVLAGLTAMGALAIDMYLPSFTAIAQDLGVGTNQVQLTLATFLIGVAVGQMFY 70 G P WL +L LTA+G L++DMYLPS IA+DL + +TL FL+ +A+GQ+ Y Sbjct: 16 GAIPGWLLLLGALTAIGPLSVDMYLPSLPTIARDLRTSSAAAGITLTAFLVSLAIGQLIY 75 Query: 71 GPLSDRFGRKPPLFFGIALYFVCSLLCIFAQNIETLIVLRLFQGLGGSAGMVIPRAMVRD 130 GP SDRFGRKPPL+ G+ALY S+ C FA + L VLR QG GG AGMVI RA VRD Sbjct: 76 GPASDRFGRKPPLYIGLALYVAASVGCAFATDATMLAVLRAVQGFGGCAGMVISRAAVRD 135 Query: 131 RMGAEGSAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTLFGLLCILGTRKYL 190 RM G+A+A+S LMLV G+APILAP IGG +L SWR IF VL FG+L + + Sbjct: 136 RMDPAGAAQAYSTLMLVMGVAPILAPMIGGAVLQVTSWRMIFAVLAAFGVLSLAAVHFLM 195 Query: 191 TETVDVSRAEPLHLGRTLRQYWGLLRHRQFMSYVLCGGLVQAGMFAYIAGGPFVVIELHG 250 E++D + A PL +GR LR YW LLR R + +Y CG + +GMFAYI PFV+I+ +G Sbjct: 196 RESLDAAHARPLAVGRVLRDYWELLRDRHYAAYTACGAVFVSGMFAYITASPFVLIDHYG 255 Query: 251 VKPQYFGFVFASNAIGLIAASQVNARLVVKRS 282 + P ++ +VF SNA G+IAAS++N RL+ + + Sbjct: 256 LSPSHYAWVFGSNAAGMIAASRINVRLMRRST 287 >PA3573 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 392 Score = 239 bits (609), Expect = 9e-63, Method: Compositional matrix adjust. Identities = 130/265 (49%), Positives = 172/265 (64%), Gaps = 1/265 (0%) Query: 17 LAVLAGLTAMGALAIDMYLPSFTAIAQDLGVGTNQVQLTLATFLIGVAVGQMFYGPLSDR 76 L +L L+A G LAID YLPSF +A+ VQL+LA + G+++GQ+ YGP++DR Sbjct: 6 LLILGALSAFGPLAIDFYLPSFPTLAKAFATDVEHVQLSLAAYFAGLSIGQLLYGPVADR 65 Query: 77 FGRKPPLFFGIALYFVCSLLCIFAQNIETLIVLRLFQGLGGSAGMVIPRAMVRDRMGAEG 136 +GR+ PL G++++ + S C A ++E LI R Q LGG AGMVI RA+VRD G Sbjct: 66 YGRRLPLLVGVSIFTLASAACALAPSLEWLIAARFVQALGGCAGMVISRAVVRDLCDPIG 125 Query: 137 SAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTLFGLLCILGTRKYLTETVDV 196 +AKAFS LMLV GLAPILAP GGL+L + W+ IFV LTLF L LG +L ET+ Sbjct: 126 AAKAFSQLMLVMGLAPILAPVAGGLLLDWQGWQSIFVCLTLFAALAGLGVALWLPETIPA 185 Query: 197 SRAEPLHLGRTLRQYWGLLRHRQFMSYVLCGGLVQAGMFAYIAGGPFVVIELHGVKPQYF 256 P L L QY L R F++Y L GG+ AGMFAYIAG P+V I+L+G+ +++ Sbjct: 186 DGERP-PLSGALGQYRRLFADRLFLAYGLSGGVAMAGMFAYIAGSPYVFIQLYGIPAEHY 244 Query: 257 GFVFASNAIGLIAASQVNARLVVKR 281 G++F SNA G I +QVNARL+ R Sbjct: 245 GWLFGSNAAGFIVMAQVNARLLRYR 269 >CC1230 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 405 Score = 220 bits (560), Expect = 4e-57, Method: Compositional matrix adjust. Identities = 118/264 (44%), Positives = 160/264 (60%), Gaps = 1/264 (0%) Query: 19 VLAGLTAMGALAIDMYLPSFTAIAQDLGVGTNQVQLTLATFLIGVAVGQMFYGPLSDRFG 78 +L LTA ++IDMYL S +I + L +Q Q TLA F G+A+GQ+FYGP SDRFG Sbjct: 18 LLGALTAFAPMSIDMYLSSLPSIGRTLNAAPDQTQATLAAFFAGMAIGQVFYGPASDRFG 77 Query: 79 RKPPLFFGIALYFVCSLLCIFAQNIETLIVLRLFQGLGGSAGMVIPRAMVRDRMGAEGSA 138 R+PPL G+ L+ S++C A NIETLI R Q LGG AG VI RA+VRDR +A Sbjct: 78 RRPPLLVGVGLFIAASIVCAVAPNIETLIAARFVQALGGCAGPVIARAVVRDRFSHTDTA 137 Query: 139 KAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTLFGLLCILGTRKYLTETVDVSR 198 + S++ L+ GLAP+LAP +GG++ A WRG+F L +FG+L LTE+ + Sbjct: 138 RVLSLMTLIMGLAPVLAPQLGGVVQFVAGWRGVFWTLVMFGVLIAAWVVLSLTESRSAAT 197 Query: 199 AEPLHLGRTLRQYWGLLRHRQFMSYVLCGGLVQAGMFAYIAGGPFVVIELHGVKPQYFGF 258 L+ Y L R+ M Y L G L A +F YI+G P +V+ +G P F Sbjct: 198 EAQARSENPLKAYVALFGMRRLMGYALAGALNGAVLFTYISGAPDLVMGTYGHSPLVFNL 257 Query: 259 VFASNAIGLIAASQVNARLVVKRS 282 VFA NA+G+I ASQ+N R +++RS Sbjct: 258 VFALNAVGIIGASQIN-RFLLRRS 280 >PA4136 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 402 Score = 209 bits (532), Expect = 9e-54, Method: Compositional matrix adjust. Identities = 123/272 (45%), Positives = 164/272 (60%), Gaps = 3/272 (1%) Query: 21 AGLTAMGALAIDMYLPSFTAIAQDLGVGTNQVQLTLATFLIGVAVGQMFYGPLSDRFGRK 80 + L A G L+IDMYLPS AIA DLG QVQ +++ FL+G VG +FYGPLSDRFGR+ Sbjct: 22 SALVAFGPLSIDMYLPSLPAIAADLGASDAQVQRSISGFLVGFCVGMLFYGPLSDRFGRR 81 Query: 81 PPLFFGIALYFVCSLLCIFAQNIETLIVLRLFQGLGGSAGMVIPRAMVRDRMGAEGSAKA 140 P L GIALY SL C A + L++LR+ Q LGG A V+ RAMVRD +A+ Sbjct: 82 PVLLAGIALYLFSSLACALADSAGQLVLLRVLQALGGGAASVLARAMVRDLYPLGEAARM 141 Query: 141 FSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTLFGLLCILGTRKYLTETVDVSRAE 200 +++ +V LAP+ AP +GG ++++A WR +FVVL LF LC+L + R Sbjct: 142 LALMHMVTMLAPLAAPLLGGYLMLWAGWRALFVVLALFAGLCLLAVWRVAESHPPERRGG 201 Query: 201 PLHLGRTLRQYWGLLRHRQFMSYVLCGGLVQAGMFAYIAGGPFVVIELHGVKPQYFGFVF 260 L + Y LL R+ + YVLC GL AGMFAYI+ PFV IE GV+ + FG+ F Sbjct: 202 --SLAQAFLAYGRLLGDRRALGYVLCMGLAFAGMFAYISAAPFVFIEHFGVRAERFGWFF 259 Query: 261 ASNAIGLIAASQVNARLVVKRSAQXGRTRAGQ 292 N +G++ A+ +ARL V+R RAG Sbjct: 260 GLNILGVMLATWCSARL-VRRHGPRPLLRAGS 290 >PM1533 [GEPR] COG0477 Permeases of the major facilitator superfamily Pmu Pasteurella multocida Length = 399 Score = 207 bits (526), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 113/276 (40%), Positives = 160/276 (57%) Query: 9 STGKFPAWLAVLAGLTAMGALAIDMYLPSFTAIAQDLGVGTNQVQLTLATFLIGVAVGQM 68 +T A + L L G L+IDMYLPS IA+ L VQL+++TFL G VG + Sbjct: 7 TTWNQTALICFLGTLVGFGPLSIDMYLPSLPTIAKALHTSIEWVQLSVSTFLTGFCVGML 66 Query: 69 FYGPLSDRFGRKPPLFFGIALYFVCSLLCIFAQNIETLIVLRLFQGLGGSAGMVIPRAMV 128 FYGPLSD++GR+ L G+ +Y V S+ C A +IE L+V R Q GG G V+ RA+V Sbjct: 67 FYGPLSDKYGRRIILLIGMTIYIVASIACSIATSIEQLLVARFLQAFGGGVGPVLGRAIV 126 Query: 129 RDRMGAEGSAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTLFGLLCILGTRK 188 RD + SM+ LV LAP+LAPFIGG++L++ W F++L L G++C L Sbjct: 127 RDSFPPQRITHVLSMMQLVTMLAPLLAPFIGGIVLLWFGWETQFLLLALIGVVCWLIAYF 186 Query: 189 YLTETVDVSRAEPLHLGRTLRQYWGLLRHRQFMSYVLCGGLVQAGMFAYIAGGPFVVIEL 248 +L ET PL+LG + Y G+L+ Q +LC + GMFAY+AG PFV I+ Sbjct: 187 FLAETNQDRHQRPLNLGTFFQAYCGILKQPQSFGNILCLSAMFGGMFAYVAGTPFVYIDY 246 Query: 249 HGVKPQYFGFVFASNAIGLIAASQVNARLVVKRSAQ 284 + PQ +GF F N +G++ A+ +N V + + Q Sbjct: 247 FHIPPQDYGFYFGINVVGIVLATLINNYCVKRYAVQ 282