BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0042.0317.p (402 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMb21000 [GEPR] COG0477 Permeases of the major facilitator super... 88 4e-17 AGc4193 [GEPR] COG0477 Permeases of the major facilitator superf... 67 8e-11 BMEI1555 [GEPR] COG0477 Permeases of the major facilitator super... 67 1e-10 yjiJ [GEPR] COG0477 Permeases of the major facilitator superfami... 66 1e-10 mlr7399 [GEPR] COG0477 Permeases of the major facilitator superf... 62 3e-09 >SMb21000 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 377 Score = 87.8 bits (216), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 105/357 (29%), Positives = 163/357 (45%), Gaps = 24/357 (6%) Query: 29 AVALGVARFSYALLLAPMRADLGWPYLVAGGMNTGNALGYLLGALATPLLMRRFLAHRVL 88 AVA+G RFSY +L M D G AG + + N +GYL GA+ V Sbjct: 2 AVAMGFGRFSYTPILPAMMTDTGLSPADAGLVASANFIGYLAGAVLAGYRWAHGRERGVG 61 Query: 89 IAGAFATALLSFLPALTTDTLLQLLLRVATGVSS--ALIFVSGGLLVSRLAAMHGHRAGL 146 +A AT LL LT+ L ++R G++S A+IF+SG +L LAA H Sbjct: 62 LAALVATTLLLAAMGLTSSVLAYSIIRFLAGLASAFAMIFISGIVLGQGLAARSEH---- 117 Query: 147 LLGLYYGGTGLGIVAASLLV---PPVMAAALAHGAAHPWQWAWLLLGTLALAASLVMAGP 203 + +++GG G GI +S+ V P A L+ A W + +ALA ++++A Sbjct: 118 VPSVHFGGVGFGIALSSIAVWVAPLAGVAGLSMSQAD-----WFVGALVALAGTVLVAA- 171 Query: 204 ARLMPTTAAHVQGNGRWQ-----ARSLLFGLIGYLFFGLGYIGYMTFVIALLKEEGMPAE 258 L+P + H GR + +R L+ + Y FFG GY+ TF++A+ ++ Sbjct: 172 --LLPAS-RHAANGGRPEVPLVRSRPLMAMTLTYGFFGFGYVITATFLVAMARDASGGHS 228 Query: 259 RITLFFALLGAATFASSRIWARMLDRFRGGQSLAILNGLLALATLLPALTAEPVAVFASG 318 L + + G + S +W + RF AI + A+ +L P A G Sbjct: 229 VEFLAWLITGVSAALSVYLWRFAVPRFGLAGVYAIGLLVEAVGLVLTVSLPSPYAPLVGG 288 Query: 319 LLFGGCFLSAVASTTAMVRHNLPPHHWPAGISAFTIIFAVGQIIGPTIVGWIADGAG 375 L+ G F+ A + R L P ++ T F +GQI+GP + GW+A+ G Sbjct: 289 LMLGATFMMVTAYGLQIGRQ-LAPESPRRALAFMTAAFGIGQIVGPLVAGWLAERTG 344 >AGc4193 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 396 Score = 67.0 bits (162), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 112/403 (27%), Positives = 164/403 (40%), Gaps = 48/403 (11%) Query: 10 SPFILQHPILTALALSLGTAVALGVARFSYALLLAPMRADLGWPYLVAGGMNTGNALGYL 69 P +H A +L A A+G RFS+ +L M AD+ AG + GN GYL Sbjct: 5 KPLSTRHLTALGFAGALMMASAMGFGRFSFTPILPGMMADVPLSAGDAGIVAAGNFAGYL 64 Query: 70 LGALATPLLMRRFLAHRVLIAGAFATALLSFLPALTTDTLLQLLLRVATGVSSALIFVSG 129 GA+ V + G F+TA L A ++R GV+SA+ + Sbjct: 65 AGAILAASSWGSGRERLVALCGLFSTAALLLAMAAFNSVAAFTVIRFLAGVASAMTMI-- 122 Query: 130 GLLVSRLAAMHGHRAGL--LLGLYYGGTGLGIVAASLLVPPVMAAALAHGAAHPWQWAWL 187 S++ H +AG + L+YGG G GI +SL V + + G W+ W+ Sbjct: 123 --FTSQIVIGHAAKAGRDSVQALHYGGVGAGIAISSLAV--YLIGVVFDGGGSSWREEWI 178 Query: 188 LLGTLALAASLVM-----AGPARLMPTTAAHVQGNGRWQARSLLFGLIGYLFFGLGYIGY 242 + A L++ AGP R + A + W R L + Y FG GY+ Sbjct: 179 AGAVFSFVAFLLVFRVLPAGPPRHASSAA---EPPLAWT-RPLFLTTLAYGLFGFGYVIT 234 Query: 243 MTFVIALLKEEGMPAERITLFFALLGAATFASSRIWARMLDRFRGGQSLAILNGLLALAT 302 TF++A+ + A L + + G A AS +W +L R ++ I+ Sbjct: 235 ATFIVAIARMAAAGAFVEFLAWFITGCAAAASLFLWKPVLKSQRLKRAFVIV-------- 286 Query: 303 LLPALTAEPVAVFASGLL------------FGGCFLSAVASTTAMVRHNLPPHHWPAGIS 350 L E V VFAS +L G F+ A + R P A + Sbjct: 287 ----LAVEAVGVFASVMLPPVAGVLAGGLLLGLTFMVITAYGLQLGREFAGPSPRRA-FA 341 Query: 351 AFTIIFAVGQIIGPTIVGWIADGAGGLQRGLSFSALMLLAGAL 393 T F GQI+GP GWIA+ G SF+A +LA A+ Sbjct: 342 LMTAAFGTGQIVGPLAAGWIAEVTG------SFTAPSILASAV 378 >BMEI1555 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 272 Score = 66.6 bits (161), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 71/236 (30%), Positives = 114/236 (48%), Gaps = 22/236 (9%) Query: 29 AVALGVARFSYALLLAPMRADLGWPYLVAGGMNTGNALGYLLGALATPLLMRRFLAHRVL 88 A A+GV RF Y +L M AD+G+ AG + + N +GYL+GA+ + V+ Sbjct: 2 AAAMGVGRFIYTPILPGMMADIGFSTADAGFIASANYIGYLVGAVVAGYGWSAGIERMVV 61 Query: 89 IAGAFATALLSFLPALTTDTLLQLLLRVATGVSSALIFV-SGGLLVSRLAAMHGHRAGLL 147 IAG A+A+ F AL + +LR A G +SA+ + +++S + RAG L Sbjct: 62 IAGLAASAVFCFAMALFDGVWILSILRFAAGFASAVTMILCTAIVLSHIT--RAQRAG-L 118 Query: 148 LGLYYGGTGLGIVAASLLVPPVMAAALAHGAAHPWQWAWLLLGTLALAASLVMAGPARLM 207 +++GG G GI ++LLV + + L W+ W+ G L L V+ + Sbjct: 119 GAMHFGGVGSGITLSALLVALIRFSGLG------WRADWIGAGLLTLVIMAVVTAFVKEG 172 Query: 208 PTTAAHVQGNGRWQA----RSLLFGLIGYLF--FGLGYIGYMTFVIALLK-EEGMP 256 P V GN + S F + + + FG GY+ TF+IA+++ +G P Sbjct: 173 P-----VGGNNGMREPPLPNSFAFHALAFAYGIFGFGYVITATFLIAIVRANDGGP 223 >yjiJ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 392 Score = 66.2 bits (160), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 103/388 (26%), Positives = 166/388 (42%), Gaps = 37/388 (9%) Query: 1 MPTDAARPPSPFILQHPILTALALSLGTAVALGVARFSYALLLAPMRADLGWPYLVAGGM 60 MP+ P F + L L+LG +G+ RF Y +L M A+ + + + Sbjct: 1 MPSST-HPVERFSFSTALFGMLVLTLG----MGLGRFLYTPMLPVMMAEGSFSFSQLSWI 55 Query: 61 NTGNALGYL-------LGALATPLLMRRFLAHRVLIAGAFATALLSFLPALTTDTLLQLL 113 +GN GYL GA P +R F L+A A A+ LL A +L LL Sbjct: 56 ASGNYAGYLAGSLLFSFGAFHQPSRLRPF-----LLASALASGLLILAMAWLPPFILVLL 110 Query: 114 LRVATGVSSALIFVSGGLLVSRLAAMHGHRAGLLLGLYYGGTGLGIVAASLLVPPVMAAA 173 +RV GV+SA + + G L+ M R +L + G G+GI + V + Sbjct: 111 IRVLAGVASAGMLIFGSTLI-----MQHTRHPFVLAALFSGVGIGIALGNEYVLAGLHFD 165 Query: 174 LAHGAAHPWQWAWLLLGTLALAASLVMAGPARLMPTT----AAHVQGNGRWQARSLLFGL 229 L+ + WQ A L G + +A +L+M P++ T A Q W ++L+GL Sbjct: 166 LS--SQTLWQGAGALSGMMLIALTLLM--PSKKHAITPMPLAKTEQQIMSWWLLAILYGL 221 Query: 230 IGYLFFGLGYIGYMTFVIALLKEEGMPAERITLFFALLGAATFASSRIWARMLDRFRGGQ 289 G+ GYI T++ + K+ G P L + L+G + W R+ Sbjct: 222 AGF-----GYIIVATYLPLMAKDAGSPLLTAHL-WTLVGLSIVPGCFGWLWAAKRWGALP 275 Query: 290 SLAILNGLLALATLLPALTAEPVAVFASGLLFGGCFLSAVASTTAMVRHNLPPHHWPAGI 349 L + A+ LL + P+ + S L FGG F+ + + R P + + Sbjct: 276 CLTANLLVQAICVLLTLASDSPLLLIISSLGFGGTFMGTTSLVMTIARQLSVPGNLNL-L 334 Query: 350 SAFTIIFAVGQIIGPTIVGWIADGAGGL 377 T+I+ +GQI+GP + +++G L Sbjct: 335 GFVTLIYGIGQILGPALTSMLSNGTSAL 362 >mlr7399 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 401 Score = 62.0 bits (149), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 107/413 (25%), Positives = 168/413 (40%), Gaps = 33/413 (7%) Query: 4 DAARPPSPFI---LQHPILTALALS----LGTAVALGVARFSYALLLAPMRADLGWPYLV 56 D P ++ ++ TAL S + AVA+G+ RF Y +L M +L Sbjct: 3 DCFSDPCIYMCAAMRSATSTALRFSVAGMIAMAVAMGIGRFVYTPILPGMMEELHLSPAN 62 Query: 57 AGGMNTGNALGYLLGALATPLLMRRFLAHRVLIAGAFATALLSFLPALTTDTLLQLLLRV 116 AG + + N LGYL+GA A +++ G A+ +L+ L LT LL+R Sbjct: 63 AGWIASANYLGYLVGAFAAAGGWAHGRERLLMLGGLGASTILAALMGLTDAMAAFLLIRF 122 Query: 117 ATGVSSALIFVSGGLLVSRLAAMHGHRAGL--LLGLYYGGTGLGIVAASLLVPPVMAAAL 174 G++SA + V ++ + H + AG L ++GG GLGI + VM A L Sbjct: 123 LAGLASAFVMV----FMASIVFSHINAAGRGDLQAWHFGGVGLGIA-----ISAVMMAVL 173 Query: 175 AHGAAHPWQWAWLLLGTLALAASLVMAGPARLMPTTAAH-VQGNGRWQARSLLFGLIGYL 233 A W WL ++ +V+A A P V+ + RSL +I Y Sbjct: 174 VTEHAG-WAAGWLWSAAISACGFVVVALLANEGPLANGQAVREPALPKDRSLTKIIIAYG 232 Query: 234 FFGLGYIGYMTFVIALLKEEGMPAERITLFFALLGAATFASSRIWARMLDRFRGGQSLAI 293 FG GY+ TF++A++++ G + + + G A F S+ +W ++ R Sbjct: 233 LFGFGYVVTATFLVAIVRQGGGSRVFEAMVWLVAGLAGFPSTWLWQKIAGRVG------- 285 Query: 294 LNGLLALATLLPALTAEPVAVFASGLLFGGCFLSAVASTTAMVRHNLPPHHWPAGISAFT 353 LN ALA L+ + L + A+ L A + Sbjct: 286 LNAAYALACLIEVIGVTASVALGGYSGPLLGGLLLGGTFIAITALGLQAARQQAPQAPRR 345 Query: 354 II------FAVGQIIGPTIVGWIADGAGGLQRGLSFSALMLLAGALTAWRQRP 400 I F +GQIIGP G +A +G +A ML+ + W P Sbjct: 346 IFALMTASFGLGQIIGPIAAGLLAQMSGDFFLASIVAAAMLVVSGVITWSAAP 398