BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0042.0294.p (215 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value MJ0915 [R] COG1712 Predicted dinucleotide-utilizing enzyme Mja M... 93 3e-19 MTH973 [R] COG1712 Predicted dinucleotide-utilizing enzyme Mth M... 85 1e-16 RSp0722 Non COG 70 3e-12 PA3505 [R] COG1712 Predicted dinucleotide-utilizing enzyme Pae P... 69 7e-12 >MJ0915 [R] COG1712 Predicted dinucleotide-utilizing enzyme Mja Methanococcus jannaschii Length = 267 Score = 93.2 bits (230), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 75/259 (28%), Positives = 117/259 (45%), Gaps = 45/259 (17%) Query: 1 MNVAIAGLGAIG-WAVAHAIDKGMPGITLSAVAVRDPDAAAERLRMLAHPPACVALASLA 59 + + I G GAIG + +D + +SAV R+ D A + L C ++ L Sbjct: 2 LKIGIVGCGAIGNFITKKVLDGTIKNAKISAVYDRNFDKA-KTLSERTGAKICSSIDDLV 60 Query: 60 DYG-DVVVECAGAHVLREIADPVLESGRQLVAMSAGGFVSSSALALLWQRYRS---QIHI 115 D+VVE A + EIA+ L + + ++ MS G L ++ +I++ Sbjct: 61 KEDLDLVVEAASIKAVEEIAEKSLINNKDVLIMSVGALADKKLFLKLRDLAKTVGRKIYL 120 Query: 116 PSGALGGLDAVAAMAEGHIDTVRLVSTKPAAALXSPYQCTG----------------AHR 159 PSGA+GGLDA+ A+ G I+ V L +TKP AAL + G + Sbjct: 121 PSGAIGGLDAIKALRLGEIEEVVLKTTKPVAALEDALKNLGYKPEDIKNPVIVFEGDVFK 180 Query: 160 TMVE----------------------LWLDPHARTNRHEVEVLADSGRLRFSMDAMP-SS 196 + E + DP+A+ N+HE+ V + G LR ++ +P Sbjct: 181 AIKEFPANINVSVTLSIAAEFPAKVVIVADPNAKLNKHELFVKSSIGTLRVCIENVPFEE 240 Query: 197 NPRTSSLAAQSVLALLRRL 215 NPRTS+LAA S + L+R L Sbjct: 241 NPRTSALAAYSAVRLIRDL 259 >MTH973 [R] COG1712 Predicted dinucleotide-utilizing enzyme Mth Methanothermobacter thermautotrophicus Length = 257 Score = 84.7 bits (208), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 71/247 (28%), Positives = 110/247 (44%), Gaps = 33/247 (13%) Query: 1 MNVAIAGLGAIGWAVAHAIDKGMPGITLSAVAVRDPDAAAERLRMLAHPPACVALASLAD 60 M V I G GAI + + G + L RD + A E L + A + +A + Sbjct: 4 MMVGIVGCGAIANLITGFVRDGRVPVKLGFFYDRDLERA-ENLASMVDGRAVLDVADMLP 62 Query: 61 YGDVVVECAGAHVLREIADPVLESGRQLVAMSAGGFVSSSALALLWQR---YRSQIHIPS 117 D+VVE A +R++ +LE+G+ +V MS G + +L + + IH+PS Sbjct: 63 EVDLVVEAASPEAVRDLVPEILEAGKDVVVMSVGALMDPELREMLVELASLNDATIHVPS 122 Query: 118 GALGGLDAVAAMAEGHIDTVRLVSTKPAAAL--------------------XSPYQCTGA 157 GA+ GLD + A + G+I++V+L++ KP +L P A Sbjct: 123 GAIVGLDGLKAASMGNIESVKLITRKPPRSLGISMDEKKVLYRGRASEAVKKFPLNINVA 182 Query: 158 --------HRTMVELWLDPHARTNRHEVEVLADSGRLR-FSMDAMPSSNPRTSSLAAQSV 208 VE+ DP N HEV V D G + + + S NP+TS +AA S Sbjct: 183 AALSLACDRDVDVEIIADPAVDRNVHEVTVRGDFGEFKTITENVRCSVNPKTSVMAAYSA 242 Query: 209 LALLRRL 215 + LL+ L Sbjct: 243 IKLLKSL 249 >RSp0722 Non COG Length = 268 Score = 70.1 bits (170), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 75/258 (29%), Positives = 102/258 (39%), Gaps = 52/258 (20%) Query: 1 MNVAIAGLGAIGWAVAHAIDKGMPGITLSAVAVRDPDAAAERLRMLAHPPA-----CVAL 55 ++V++ G GAIG V + K P + V V P+ +R R P A L Sbjct: 2 LHVSMVGCGAIGQGVLELL-KSDPDLCFDTVIV--PEHGMDRARAAIAPFAPRTRVMTRL 58 Query: 56 ASLADYGDVVVECAGAHVLREIADPVLESGRQLVAMSAGGFVS---SSALALLWQRYRSQ 112 + AD D++VECAG LRE P LE G + +S G + L +R +Q Sbjct: 59 PAQADRPDLLVECAGHDALREHVVPALEQGIDCLVVSVGALSEPGLAERLEAAARRGHAQ 118 Query: 113 IHIPSGALGGLDAVAAMAEGHIDTVRLVSTKPA--------------------------- 145 + + SGA+G +DA+AA G +D V KP Sbjct: 119 MQLLSGAIGAIDALAAARVGGLDAVVYTGRKPPRAWKGTPAERQFDLDALDRTTVIFEGK 178 Query: 146 ---AALXSPYQCT----------GAHRTMVELWLDPHARTNRHEVEVLADSGRLRFSMDA 192 AAL P G RT V L DP N H VE G M Sbjct: 179 ASDAALLFPKNANVAATLALAGLGMERTHVRLLADPTIDENIHHVEARGAFGGFELIMRG 238 Query: 193 MP-SSNPRTSSLAAQSVL 209 P ++NP+TS+L SV+ Sbjct: 239 KPLAANPKTSALTVFSVV 256 >PA3505 [R] COG1712 Predicted dinucleotide-utilizing enzyme Pae Pseudomonas aeruginosa Length = 267 Score = 68.9 bits (167), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 68/255 (26%), Positives = 107/255 (41%), Gaps = 47/255 (18%) Query: 1 MNVAIAGLGAIGWAVAHAIDKGMPGITLSAVAV-RDPDAAAE-RLRMLAHPPACVALASL 58 +N+ + G GAIG V ++ P + + AV V RD + RL L PP ++ Sbjct: 2 LNIVMIGCGAIGAGVLELLEND-PQLRVDAVIVPRDSETQVRHRLASLRRPPRVLSALPA 60 Query: 59 ADYGDVVVECAGAHVLREIADPVLESGRQLVAMSAGGFVSSSALALLW---QRYRSQIHI 115 + D++VECAG + + P L G + +S G + L Q S+I + Sbjct: 61 GERPDLLVECAGHRAIEQHVLPALAQGIPCLVVSVGALSEPGLVERLEAAAQAGGSRIEL 120 Query: 116 PSGALGGLDAVAAMAEGHIDTVRLVSTKPAAA-LXSPYQCT------------------- 155 GA+G +DA++A G +++VR KPA+A L +P + Sbjct: 121 LPGAIGAIDALSAARVGGLESVRYTGRKPASAWLGTPGETVCDLQRLEKARVIFDGSARE 180 Query: 156 --------------------GAHRTMVELWLDPHARTNRHEVEVLADSGRLRFSMDAMP- 194 G RT V L DP + N H+VE G ++ P Sbjct: 181 AARLYPKNANVAATLSLAGLGLDRTQVRLIADPESCENVHQVEASGAFGGFELTLRGKPL 240 Query: 195 SSNPRTSSLAAQSVL 209 ++NP+TS+L SV+ Sbjct: 241 AANPKTSALTVYSVV 255