BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0042.0288.p (216 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0139 [F] COG0461 Orotate phosphoribosyltransferase Rso Ralsto... 321 6e-88 NMB1874 [F] COG0461 Orotate phosphoribosyltransferase Nme Neisse... 251 1e-66 NMA0582 [F] COG0461 Orotate phosphoribosyltransferase NmA Neisse... 251 1e-66 STM3733 [F] COG0461 Orotate phosphoribosyltransferase Sty Salmon... 239 3e-63 YPO0045 [F] COG0461 Orotate phosphoribosyltransferase Ype Yersin... 238 6e-63 >RSc0139 [F] COG0461 Orotate phosphoribosyltransferase Rso Ralstonia solanacearum Length = 237 Score = 321 bits (823), Expect = 6e-88, Method: Compositional matrix adjust. Identities = 160/216 (74%), Positives = 182/216 (84%) Query: 1 LRQEFIEFAVSAGVLRFGEFVTKAGRTSPYFFNAGLFSEGATLAQVARFYAQTLQDSGVE 60 LRQ FI FAV AGVL FGEFVTKAGRTSPYFFNAG FS+GA L QVA+FYA+TL DSGV+ Sbjct: 18 LRQSFIRFAVEAGVLSFGEFVTKAGRTSPYFFNAGKFSDGALLGQVAQFYAKTLLDSGVQ 77 Query: 61 YDMLFGPAYKGITLASATAVALAGMGRNVPFAFNRKEAKDHGEGGTIVGAKLQGKVVIID 120 +DMLFGPAYKGITLASATAVALAGMGRNV FA+NRKEAKDHGEGG++VGAKLQG+VVI+D Sbjct: 78 FDMLFGPAYKGITLASATAVALAGMGRNVGFAYNRKEAKDHGEGGSLVGAKLQGRVVIVD 137 Query: 121 DVISAGTSVRESVDMIRAAGATPCAVLIALDRMERSGKDGALSALSAVQEVAREYDMPVI 180 DVISAGTSVRESV++IR AGATP AVLI +DRMERSG + SAVQ+V +Y MPV+ Sbjct: 138 DVISAGTSVRESVELIRNAGATPAAVLILMDRMERSGNAVDIGERSAVQDVQAQYGMPVV 197 Query: 181 SIGNLNDLFEYISNGGDARLAQYKDAVAAYRTRYGV 216 SI NL+DL Y+ + GD LA Y+ AAYR +YGV Sbjct: 198 SIANLDDLLGYLDHAGDPALAGYRAKAAAYRDKYGV 233 >NMB1874 [F] COG0461 Orotate phosphoribosyltransferase Nme Neisseria meningitidis MC58 Length = 213 Score = 251 bits (640), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 130/216 (60%), Positives = 167/216 (77%), Gaps = 7/216 (3%) Query: 1 LRQEFIEFAVSAGVLRFGEFVTKAGRTSPYFFNAGLFSEGATLAQVARFYAQTLQDSGVE 60 RQ+F++F+++ VL+FGEF TKAGR SPYFFNAGLF++G + Q+A+FYAQ++ +SG+ Sbjct: 4 FRQDFLKFSLAQNVLKFGEFTTKAGRRSPYFFNAGLFNDGLSTLQLAKFYAQSIIESGIR 63 Query: 61 YDMLFGPAYKGITLASATAVALAGMGRNVPFAFNRKEAKDHGEGGTIVGAKLQGKVVIID 120 +DMLFGPAYKGI LA+ATA+ LA G NVPFA+NRKEAKDHGEGG +VGA L+G+V+IID Sbjct: 64 FDMLFGPAYKGIILAAATAMMLAEKGVNVPFAYNRKEAKDHGEGGVLVGAPLKGRVLIID 123 Query: 121 DVISAGTSVRESVDMIRAAGATPCAVLIALDRMERSGKDGALSALSAVQEVAREYDMPVI 180 DVISAGTSVRES+ +I A GATP V IALDRME+ + LSAVQEV ++Y +PV Sbjct: 124 DVISAGTSVRESIKLIEAEGATPAGVAIALDRMEKGTGE-----LSAVQEVEKQYGLPVA 178 Query: 181 SIGNLNDLFEYISNGGDARLAQYKDAVAAYRTRYGV 216 I +LNDLF + N + Q+ + V AYR +YGV Sbjct: 179 PIASLNDLFILLQN--NPEFGQFLEPVRAYRRQYGV 212 >NMA0582 [F] COG0461 Orotate phosphoribosyltransferase NmA Neisseria meningitidis Z2491 Length = 213 Score = 251 bits (640), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 130/216 (60%), Positives = 167/216 (77%), Gaps = 7/216 (3%) Query: 1 LRQEFIEFAVSAGVLRFGEFVTKAGRTSPYFFNAGLFSEGATLAQVARFYAQTLQDSGVE 60 RQ+F++F+++ VL+FGEF TKAGR SPYFFNAGLF++G + Q+A+FYAQ++ +SG+ Sbjct: 4 FRQDFLKFSLAQNVLKFGEFTTKAGRRSPYFFNAGLFNDGLSTLQLAKFYAQSIIESGIR 63 Query: 61 YDMLFGPAYKGITLASATAVALAGMGRNVPFAFNRKEAKDHGEGGTIVGAKLQGKVVIID 120 +DMLFGPAYKGI LA+ATA+ LA G NVPFA+NRKEAKDHGEGG +VGA L+G+V+IID Sbjct: 64 FDMLFGPAYKGIILAAATAMMLAEKGVNVPFAYNRKEAKDHGEGGVLVGAPLKGRVLIID 123 Query: 121 DVISAGTSVRESVDMIRAAGATPCAVLIALDRMERSGKDGALSALSAVQEVAREYDMPVI 180 DVISAGTSVRES+ +I A GATP V IALDRME+ + LSAVQEV ++Y +PV Sbjct: 124 DVISAGTSVRESIKLIEAEGATPAGVAIALDRMEKGTGE-----LSAVQEVEKQYGLPVA 178 Query: 181 SIGNLNDLFEYISNGGDARLAQYKDAVAAYRTRYGV 216 I +LNDLF + N + Q+ + V AYR +YGV Sbjct: 179 PIASLNDLFILLQN--NPEFGQFLEPVRAYRRQYGV 212 >STM3733 [F] COG0461 Orotate phosphoribosyltransferase Sty Salmonella typhimurium LT2 Length = 213 Score = 239 bits (610), Expect = 3e-63, Method: Compositional matrix adjust. Identities = 120/216 (55%), Positives = 163/216 (75%), Gaps = 8/216 (3%) Query: 2 RQEFIEFAVSAGVLRFGEFVTKAGRTSPYFFNAGLFSEGATLAQVARFYAQTLQDSGVEY 61 +++FIEFA++ VL+FGEF K+GR SPYFFNAGLF+ G LA + RFYA+ L DSG+E+ Sbjct: 5 QRQFIEFALNKQVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLALLGRFYAEALVDSGIEF 64 Query: 62 DMLFGPAYKGITLASATAVALA-GMGRNVPFAFNRKEAKDHGEGGTIVGAKLQGKVVIID 120 D+LFGPAYKGI +A+ TAVALA +++P+ FNRKEAKDHGEGG++VG+ LQG+V+++D Sbjct: 65 DLLFGPAYKGIPIATTTAVALAEHHDKDLPYCFNRKEAKDHGEGGSLVGSALQGRVMLVD 124 Query: 121 DVISAGTSVRESVDMIRAAGATPCAVLIALDRMERSGKDGALSALSAVQEVAREYDMPVI 180 DVI+AGT++RES+++I+A GAT VLI+LDR ER + +SA+QEV R+Y VI Sbjct: 125 DVITAGTAIRESMEIIQAHGATLAGVLISLDRQERGRGE-----ISAIQEVERDYGCKVI 179 Query: 181 SIGNLNDLFEYISNGGDARLAQYKDAVAAYRTRYGV 216 SI L DL Y+ D +A++ AV AYR +GV Sbjct: 180 SIITLKDLIAYLEEKPD--MAEHLAAVRAYREEFGV 213 >YPO0045 [F] COG0461 Orotate phosphoribosyltransferase Ype Yersinia pestis Length = 215 Score = 238 bits (607), Expect = 6e-63, Method: Compositional matrix adjust. Identities = 119/216 (55%), Positives = 160/216 (74%), Gaps = 8/216 (3%) Query: 2 RQEFIEFAVSAGVLRFGEFVTKAGRTSPYFFNAGLFSEGATLAQVARFYAQTLQDSGVEY 61 ++EFIEFA++ VL+FGEF K+GR SPYFFNAGLF+ G LA++ RFYA L D GVE+ Sbjct: 5 QREFIEFALNKQVLKFGEFTLKSGRISPYFFNAGLFNTGLDLAKLGRFYAAALMDCGVEF 64 Query: 62 DMLFGPAYKGITLASATAVALA-GMGRNVPFAFNRKEAKDHGEGGTIVGAKLQGKVVIID 120 D+LFGPAYKGI +A+ TAVALA R+VP+ FNRKEAK HGEGG +VG+ LQG+V+++D Sbjct: 65 DLLFGPAYKGIPIATTTAVALAEHHERDVPYCFNRKEAKTHGEGGNLVGSPLQGRVMLVD 124 Query: 121 DVISAGTSVRESVDMIRAAGATPCAVLIALDRMERSGKDGALSALSAVQEVAREYDMPVI 180 DVI+AGT++RES+++I A GAT V+I+LDR ER + +SA+QEV R+Y VI Sbjct: 125 DVITAGTAIRESMEIINAQGATLAGVMISLDRQERGRGE-----ISAIQEVERDYHCKVI 179 Query: 181 SIGNLNDLFEYISNGGDARLAQYKDAVAAYRTRYGV 216 +I LND+ Y+ + +A++ AV YR +YGV Sbjct: 180 AIVTLNDVIRYLED--KPEMAEHLVAVRQYREQYGV 213