BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0042.0286.p         (164 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSc0333 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins ...   196   1e-50
NMB1958 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins ...   117   1e-26
NMA0493 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins ...   114   1e-25
BH1577 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins B...    91   1e-18
BS_resA [OC] COG0526 Thiol-disulfide isomerase and thioredoxins ...    80   2e-15

>RSc0333 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Rso
           Ralstonia solanacearum
          Length = 213

 Score =  196 bits (499), Expect = 1e-50,   Method: Compositional matrix adjust.
 Identities = 88/149 (59%), Positives = 113/149 (75%)

Query: 9   VVAAIAAFTYFKVNAGNAAPDVTFTKLDGQQVNLKDLRGKVVMVNFWATSCTTCVGEMPQ 68
           V+AA   F +   +     P  +FT LDGQ+++ +DL+GKV +VNFWATSC TCV EMP 
Sbjct: 58  VLAAAGWFGWRAFSPSQQVPAASFTLLDGQKLSTRDLKGKVYLVNFWATSCATCVKEMPN 117

Query: 69  MIDTYNKFKDRGLDFVAVAMSYDPPNYVLNYTETRKLPFKVALDPQDTLAKAFGDVKLTP 128
           MI TYNKFK +GL+FVAVAM YDPP YV+NY++TR+LPFKVA+D     A+AFGDV+LTP
Sbjct: 118 MIQTYNKFKGQGLEFVAVAMRYDPPMYVMNYSQTRQLPFKVAMDADGAAARAFGDVQLTP 177

Query: 129 TTFVIDKQGNIIKRYVGEPQFAELHQLLE 157
           TTF++D+ G I+KRYVGEP++A    LL 
Sbjct: 178 TTFLVDRDGRILKRYVGEPEWAAFETLLR 206


>NMB1958 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Nme
           Neisseria meningitidis MC58
          Length = 166

 Score =  117 bits (292), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 63/165 (38%), Positives = 92/165 (55%), Gaps = 2/165 (1%)

Query: 1   MIKLAALAVVAAIAAF-TYFKVNAGNAAPDVTFTKLDGQQVNLKDLRGKVVMVNFWATSC 59
           M K+   AVVA I        +     AP  +   L G+ V+  DL+GKV ++NFW  SC
Sbjct: 1   MKKILTAAVVALIGILLAIVLIPDSKTAPAFSLPDLHGKTVSNADLQGKVTLINFWFPSC 60

Query: 60  TTCVGEMPQMIDTYNKFKDRGLDFVAVAMSYDPPNYVLNYTETRKLPFKVALDPQDTLAK 119
             CV EMP++I T N +K++    +AVA   DP   V  Y +   LPF V  D    + +
Sbjct: 61  PGCVSEMPKIIKTANDYKNKNFQVLAVAQPIDPIESVRQYVKDYGLPFTVMYDADKAVGQ 120

Query: 120 AFGDVKLTPTTFVIDKQGNIIKRYVGEPQFAELHQLLEKRYRFSN 164
           AFG  ++ PT+ +I K+G I+K YVGEP F +L+Q ++  +R S+
Sbjct: 121 AFG-TQVYPTSVLIGKKGEILKTYVGEPDFGKLYQEIDTAWRNSD 164


>NMA0493 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins NmA
           Neisseria meningitidis Z2491
          Length = 162

 Score =  114 bits (285), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 61/158 (38%), Positives = 89/158 (56%), Gaps = 2/158 (1%)

Query: 1   MIKLAALAVVAAIAAF-TYFKVNAGNAAPDVTFTKLDGQQVNLKDLRGKVVMVNFWATSC 59
           M K+   AVVA I        +     AP  + + L G+ V+  DL+GKV ++NFW  SC
Sbjct: 1   MKKILTAAVVALIGILLAIVLIPDSKTAPAFSLSDLHGKTVSNADLQGKVTLINFWFPSC 60

Query: 60  TTCVGEMPQMIDTYNKFKDRGLDFVAVAMSYDPPNYVLNYTETRKLPFKVALDPQDTLAK 119
             CV EMP++I T N +K++    +AVA   DP   V  Y +   LPF V  D    + +
Sbjct: 61  PGCVSEMPKIIKTANDYKNKNFQVLAVAQPIDPIESVRQYVKDYGLPFTVMYDADKAVGQ 120

Query: 120 AFGDVKLTPTTFVIDKQGNIIKRYVGEPQFAELHQLLE 157
           AFG  ++ PT+ +I K+G I+K YVGEP F +L+Q ++
Sbjct: 121 AFG-TQVYPTSVLIGKKGEILKTYVGEPDFGKLYQEID 157


>BH1577 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Bha
           Bacillus halodurans
          Length = 176

 Score = 90.9 bits (224), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 45/152 (29%), Positives = 82/152 (53%), Gaps = 10/152 (6%)

Query: 2   IKLAALAVVAAIAAFTYFK--------VNAGNAAPDVTFTKLDGQQVNLKDLRGKVVMVN 53
           ++L+ LAV++    +T++           AG  A +     L+G+ + L++L GK V +N
Sbjct: 9   MRLSILAVISVALGYTFYSNFFADRSLARAGEQAVNFVLEDLEGESIELRELEGKGVFLN 68

Query: 54  FWATSCTTCVGEMPQMIDTYNKFKDRGLDFVAVAMSYDPPNYVLNYTETRKLPFKVALDP 113
           FW T C  C  EMP M   Y ++K++G++ +AV  + +P   V  + +   L F + +D 
Sbjct: 69  FWGTYCPPCEREMPHMEKLYGEYKEQGVEIIAVNAN-EPELTVQRFVDRYGLSFPIVIDK 127

Query: 114 QDTLAKAFGDVKLTPTTFVIDKQGNIIKRYVG 145
              +  A+G ++  PTT +I++ G I+K + G
Sbjct: 128 GLNVIDAYG-IRPLPTTILINEHGEIVKVHTG 158


>BS_resA [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Bsu
           Bacillus subtilis
          Length = 181

 Score = 80.1 bits (196), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 43/130 (33%), Positives = 70/130 (53%), Gaps = 2/130 (1%)

Query: 27  APDVTFTKLDGQQVNLKDLRGKVVMVNFWATSCTTCVGEMPQMIDTYNKFKDRGLDFVAV 86
           AP+      +G+++ L DL+GK V +NFW T C  C  E P M + Y  FK +G++ VAV
Sbjct: 44  APNFVLEDTNGKRIELSDLKGKGVFLNFWGTWCEPCKKEFPYMANQYKHFKSQGVEIVAV 103

Query: 87  AMSYDPPNYVLNYTETRKLPFKVALDPQDTLAKAFGDVKLTPTTFVIDKQGNIIKRYVGE 146
            +  +    V N+ ++  + F V LD    +  A+ DV   PTTF+I+ +G ++K   G 
Sbjct: 104 NVG-ESKIAVHNFMKSYGVNFPVVLDTDRQVLDAY-DVSPLPTTFLINPEGKVVKVVTGT 161

Query: 147 PQFAELHQLL 156
              + +H  +
Sbjct: 162 MTESMIHDYM 171