BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0042.0225.p (410 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGc2694 [GEPR] COG0477 Permeases of the major facilitator superf... 256 6e-68 Rv2456c [GEPR] COG0477 Permeases of the major facilitator superf... 242 1e-63 MT2531 [GEPR] COG0477 Permeases of the major facilitator superfa... 242 1e-63 >AGc2694 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 498 Score = 256 bits (654), Expect = 6e-68, Method: Compositional matrix adjust. Identities = 166/398 (41%), Positives = 233/398 (58%), Gaps = 5/398 (1%) Query: 11 LSRLNFCLADVRDGLGPFLGVFLMGQGWAADDIGYVMTLGGIAGMLATTPAGALTDAVRA 70 L+ LNF LAD RDGLGPFL FL QGW++ +G + T+GG+ G+LAT GAL D Sbjct: 105 LAALNFFLADARDGLGPFLDAFLATQGWSSLSLGMIATVGGLVGLLATPLCGALVDGTTW 164 Query: 71 KRLVVGLGSVLVVAGSLLLLISPSFTVTAISQVGTGIVGAIIGPAIAGLTLGIVGQQGLP 130 KR+++ + VLV G+L+ LI P + Q+ T +VGA++GPA+AGLTLG+VG++ Sbjct: 165 KRMLIAIPVVLVTIGALITLIFPDAWIVWTGQIMTAVVGAVVGPALAGLTLGLVGERLFS 224 Query: 131 SQLGRNEAWNHAGNVFSATLAGALGYFWGLPAVFVLMAVMAVASLLCLSRIRPEDIDHDV 190 +Q+ RNE WNH GN S + F+G+ + LM + A +L+ + I P IDH V Sbjct: 225 NQISRNEFWNHGGNFASLFATYVVVTFFGMNGIIGLMLLTAAGALVATAAIDPARIDHKV 284 Query: 191 ARGLDPQRTGGKPEASTWRVLASSRPLMLLALAMMLFHLGNAAMLPLLGQSAVSRGGADP 250 ARGL + G+P S VL R L+ LA+ +++FH GNA M L+ Q + P Sbjct: 285 ARGLAEDK--GEPGPSGINVLLHERGLIFLAIILLVFHFGNAPMGRLIAQD-FAIELQTP 341 Query: 251 ALYTALTVIVAQLVMIPTALFAGRFADRKGYWLLITIALLALPLRGMVAGVWDSPWALLP 310 TA+ VAQ MI A A R G + +AL ALP+RG++A + W + P Sbjct: 342 FRTTAIITGVAQFAMIFVAAMAPWLIRRFGLSTVFIVALAALPIRGLLASAFTDFWVIFP 401 Query: 311 VQMLDGVGAGLLGVALPGSVARILHGSGHINIGLGAVTTIQSIGAALSPALAGVVARHYG 370 VQ LDGVGAGLLG+ P +V RIL G+G N+GL +V +Q IGA+LS +AG + G Sbjct: 402 VQFLDGVGAGLLGIVTPVAVERILKGTGRFNVGLASVMMVQGIGASLSNVVAGWLVTKGG 461 Query: 371 YGAAFAVLTGIALLALAVWAWLAERRDHAPQGSPAAAA 408 Y + V GIA +A+ + +L R + AP+ A+ Sbjct: 462 YSLSHLVGGGIAAIAIGL--FLLYRNEIAPKQDDDGAS 497 >Rv2456c [GEPR] COG0477 Permeases of the major facilitator superfamily Mtu Mycobacterium tuberculosis H37Rv Length = 418 Score = 242 bits (618), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 159/373 (42%), Positives = 222/373 (59%), Gaps = 1/373 (0%) Query: 11 LSRLNFCLADVRDGLGPFLGVFLM-GQGWAADDIGYVMTLGGIAGMLATTPAGALTDAVR 69 L LNF LADVRDGLGP+L ++L+ W IG+VM +GGIA ++A TP GAL D Sbjct: 16 LDLLNFSLADVRDGLGPYLSIYLLLIHDWDQASIGFVMAVGGIAAIVAQTPIGALVDRTT 75 Query: 70 AKRLVVGLGSVLVVAGSLLLLISPSFTVTAISQVGTGIVGAIIGPAIAGLTLGIVGQQGL 129 AKR +V G+VLV A ++ + + ++ Q TGI ++ PA+A +TLG VG Q Sbjct: 76 AKRALVVAGAVLVTAAAVAMPLFAGLYSISVLQAVTGIASSVFAPALAAITLGAVGPQFF 135 Query: 130 PSQLGRNEAWNHAGNVFSATLAGALGYFWGLPAVFVLMAVMAVASLLCLSRIRPEDIDHD 189 ++GRNEA+NHAGN +A GAL YF+G VF ++A MA+ S+L RI P+ +DHD Sbjct: 136 ARRIGRNEAFNHAGNASAAGATGALAYFFGPVVVFWVLAGMALISVLATLRIPPDAVDHD 195 Query: 190 VARGLDPQRTGGKPEASTWRVLASSRPLMLLALAMMLFHLGNAAMLPLLGQSAVSRGGAD 249 +ARG+D P+ S + VLA +R L++ A++ FH NAAMLPL+G+ + Sbjct: 196 LARGMDHAPGEPHPQPSRFTVLAHNRELVIFGAAVVAFHFANAAMLPLVGELLALHNRDE 255 Query: 250 PALYTALTVIVAQLVMIPTALFAGRFADRKGYWLLITIALLALPLRGMVAGVWDSPWALL 309 + ++ AQ+VM+P A G AD G + + L RG + + D+ + L+ Sbjct: 256 GTALMSSCIVAAQVVMVPVAYVVGTRADAWGRKPIFLVGFAVLTARGFLYTLSDNSYWLV 315 Query: 310 PVQMLDGVGAGLLGVALPGSVARILHGSGHINIGLGAVTTIQSIGAALSPALAGVVARHY 369 VQ+LDG+GAG+ G P V + HG+GH NI LGAVTT IGAALS +AG + Sbjct: 316 GVQLLDGIGAGIFGALFPLVVQDVTHGTGHFNISLGAVTTATGIGAALSNLVAGWIVVVA 375 Query: 370 GYGAAFAVLTGIA 382 GY AAF L +A Sbjct: 376 GYDAAFMSLGALA 388 >MT2531 [GEPR] COG0477 Permeases of the major facilitator superfamily MtC Mycobacterium tuberculosis CDC1551 Length = 418 Score = 242 bits (618), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 159/373 (42%), Positives = 222/373 (59%), Gaps = 1/373 (0%) Query: 11 LSRLNFCLADVRDGLGPFLGVFLM-GQGWAADDIGYVMTLGGIAGMLATTPAGALTDAVR 69 L LNF LADVRDGLGP+L ++L+ W IG+VM +GGIA ++A TP GAL D Sbjct: 16 LDLLNFSLADVRDGLGPYLSIYLLLIHDWDQASIGFVMAVGGIAAIVAQTPIGALVDRTT 75 Query: 70 AKRLVVGLGSVLVVAGSLLLLISPSFTVTAISQVGTGIVGAIIGPAIAGLTLGIVGQQGL 129 AKR +V G+VLV A ++ + + ++ Q TGI ++ PA+A +TLG VG Q Sbjct: 76 AKRALVVAGAVLVTAAAVAMPLFAGLYSISVLQAVTGIASSVFAPALAAITLGAVGPQFF 135 Query: 130 PSQLGRNEAWNHAGNVFSATLAGALGYFWGLPAVFVLMAVMAVASLLCLSRIRPEDIDHD 189 ++GRNEA+NHAGN +A GAL YF+G VF ++A MA+ S+L RI P+ +DHD Sbjct: 136 ARRIGRNEAFNHAGNASAAGATGALAYFFGPVVVFWVLAGMALISVLATLRIPPDAVDHD 195 Query: 190 VARGLDPQRTGGKPEASTWRVLASSRPLMLLALAMMLFHLGNAAMLPLLGQSAVSRGGAD 249 +ARG+D P+ S + VLA +R L++ A++ FH NAAMLPL+G+ + Sbjct: 196 LARGMDHAPGEPHPQPSRFTVLAHNRELVIFGAAVVAFHFANAAMLPLVGELLALHNRDE 255 Query: 250 PALYTALTVIVAQLVMIPTALFAGRFADRKGYWLLITIALLALPLRGMVAGVWDSPWALL 309 + ++ AQ+VM+P A G AD G + + L RG + + D+ + L+ Sbjct: 256 GTALMSSCIVAAQVVMVPVAYVVGTRADAWGRKPIFLVGFAVLTARGFLYTLSDNSYWLV 315 Query: 310 PVQMLDGVGAGLLGVALPGSVARILHGSGHINIGLGAVTTIQSIGAALSPALAGVVARHY 369 VQ+LDG+GAG+ G P V + HG+GH NI LGAVTT IGAALS +AG + Sbjct: 316 GVQLLDGIGAGIFGALFPLVVQDVTHGTGHFNISLGAVTTATGIGAALSNLVAGWIVVVA 375 Query: 370 GYGAAFAVLTGIA 382 GY AAF L +A Sbjct: 376 GYDAAFMSLGALA 388