BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0042.0187.p         (176 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

CAC3465 [Q] COG1335 Amidases related to nicotinamidase Cac Clost...    99   6e-21
L125244 [Q] COG1335 Amidases related to nicotinamidase Lla Lacto...    98   1e-20
SP1745 [Q] COG1335 Amidases related to nicotinamidase Spn Strept...    96   5e-20
STM1902 [Q] COG1335 Amidases related to nicotinamidase Sty Salmo...    79   5e-15
AGc456 [Q] COG1335 Amidases related to nicotinamidase Atu Agroba...    79   5e-15

>CAC3465 [Q] COG1335 Amidases related to nicotinamidase Cac Clostridium
           acetobutylicum
          Length = 178

 Score = 98.6 bits (244), Expect = 6e-21,   Method: Compositional matrix adjust.
 Identities = 44/155 (28%), Positives = 88/155 (56%), Gaps = 4/155 (2%)

Query: 4   ALLIIDIQHALCHGPDAVENSAAVIDRVNQLADQARAAGAPVIFVQHEDEDA--LQRGSE 61
            L+++D Q+ L        N   VI+ + +L   ARA    V++V+H+D +   L++G+E
Sbjct: 5   VLMVVDAQNGLIKKKPY--NHKNVIENIKKLIIMARANNKEVVYVRHDDGEGTELEKGTE 62

Query: 62  GWQLMPGLHQQPEDLHLPKRGSDAFHHTELQAMLKMRHISALVICGMQTEYCVESTVRRA 121
           GWQ+   L  +  +  + K+ + AFH T+L+  L+ ++   +++ G+QTEYC+++T++ A
Sbjct: 63  GWQIYSELEPKSGEFIIEKKYNSAFHRTDLKEYLESKNTDTIILVGLQTEYCIDATLKSA 122

Query: 122 LALGYPVMLAADAHTTAPNGVLTVAQVIAHHHATL 156
               Y V++  D +TT  N  L+  ++   ++  +
Sbjct: 123 FDNEYKVIIPKDTNTTFDNEYLSGEKLYKFYNYKI 157


>L125244 [Q] COG1335 Amidases related to nicotinamidase Lla Lactococcus
           lactis
          Length = 176

 Score = 97.8 bits (242), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 50/153 (32%), Positives = 84/153 (54%), Gaps = 4/153 (2%)

Query: 4   ALLIIDIQHALCHGPDAVENSAAVIDRVNQLADQARAAGAPVIFVQHEDEDALQRGSEGW 63
           AL++ID+Q+ +C G   +     +I+++NQ     R A  P+IF+QH D D L + S GW
Sbjct: 18  ALIVIDMQNEVCAG---IYRREELIEQINQRILTYRKAKKPIIFIQHND-DELIKESFGW 73

Query: 64  QLMPGLHQQPEDLHLPKRGSDAFHHTELQAMLKMRHISALVICGMQTEYCVESTVRRALA 123
           Q++P L     D ++ K  ++ F+ TELQ +L    +  +  CG QTE+CV +T+  A  
Sbjct: 74  QMIPELLTASTDKYVEKTHANGFYQTELQKLLTDLSVKLIEFCGAQTEFCVNTTLVFAHG 133

Query: 124 LGYPVMLAADAHTTAPNGVLTVAQVIAHHHATL 156
           LGY   +   A +T  +  L+  +++  +   L
Sbjct: 134 LGYQNWMQRGASSTFDSKWLSAKEIVDFYEKHL 166


>SP1745 [Q] COG1335 Amidases related to nicotinamidase Spn Streptococcus
           pneumoniae TIGR4
          Length = 166

 Score = 95.5 bits (236), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 48/137 (35%), Positives = 82/137 (59%), Gaps = 4/137 (2%)

Query: 1   MPTALLIIDIQHALCHGPDAVENSAAVIDRVNQLADQARAAGAPVIFVQHEDEDALQRGS 60
           M TA +IID+Q+ L         + +++++++ L +QAR+    +I+VQH  E++  + S
Sbjct: 1   MKTAFIIIDVQNVLVETGF---QTKSLLEKISYLQNQARSKNIEIIYVQH-IENSEAQTS 56

Query: 61  EGWQLMPGLHQQPEDLHLPKRGSDAFHHTELQAMLKMRHISALVICGMQTEYCVESTVRR 120
           E WQL   L+++P +    K+ +  F  T L+  L  + I  LV+CGMQTEYCV+++V+ 
Sbjct: 57  EDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLCGMQTEYCVDTSVKV 116

Query: 121 ALALGYPVMLAADAHTT 137
           A   GY +++   A TT
Sbjct: 117 AFEYGYQLIVPEGAVTT 133


>STM1902 [Q] COG1335 Amidases related to nicotinamidase Sty Salmonella
           typhimurium LT2
          Length = 188

 Score = 79.0 bits (193), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 49/151 (32%), Positives = 81/151 (53%), Gaps = 15/151 (9%)

Query: 3   TALLIIDIQHALCHGPDAVENSAAVIDRVNQLADQARAAGAPVIFVQ--HEDE--DALQR 58
           TAL++ID+Q  +         +  V+ R  +LA++ RA G+PV+ V+    D+  +AL++
Sbjct: 9   TALVVIDLQEGILPFAGGPYTANEVVARAARLAEKCRANGSPVVMVRVGWSDDYAEALKQ 68

Query: 59  G----------SEGWQLMP-GLHQQPEDLHLPKRGSDAFHHTELQAMLKMRHISALVICG 107
                       E W   P  L ++  DL + KR   AF+ T+L+  L+ R I  +++CG
Sbjct: 69  PVDAATPAHALPENWWTWPTALGKKDSDLEVTKRQWGAFYGTDLELQLRRRGIDTIILCG 128

Query: 108 MQTEYCVESTVRRALALGYPVMLAADAHTTA 138
           + T   VEST R A  LG+ +++A DA + A
Sbjct: 129 ISTNIGVESTARNAWELGFNLIIAEDACSAA 159


>AGc456 [Q] COG1335 Amidases related to nicotinamidase Atu Agrobacterium
           tumefaciens strain C58 (Cereon)
          Length = 239

 Score = 79.0 bits (193), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 52/139 (37%), Positives = 75/139 (53%), Gaps = 3/139 (2%)

Query: 3   TALLIIDIQHALCHGPDAVENS-AAVIDRVNQLADQARAAGAPVIFVQHEDED-ALQRGS 60
           TALL+ID+Q +  H P   E+  AA +++   L D A+AAG PV+ + H D D A  + S
Sbjct: 59  TALLVIDVQESFRHAPYFEESGLAAYLEKQQALIDGAKAAGIPVVQIFHVDGDRAFSKDS 118

Query: 61  EGWQLMPGLHQQPEDLHLPKRGSDAFHHTELQAMLKMRHISALVICGMQTEYCVESTVRR 120
              + + G+   P D+   K    AF  T L+  L  R I+ L++ G++TE C E+T R 
Sbjct: 119 GYIRALEGVRITP-DVTFHKSRHSAFAGTGLEIWLTQRGINRLIVSGIRTEQCCETTTRH 177

Query: 121 ALALGYPVMLAADAHTTAP 139
           A  LGY V    +A  T P
Sbjct: 178 ASDLGYSVDYITEATLTFP 196