BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0042.0180.p (274 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3467 [GEPR] COG0477 Permeases of the major facilitator superfa... 128 1e-29 PAE2330 [GEPR] COG0477 Permeases of the major facilitator superf... 119 7e-27 TVN0436 [GEPR] COG0477 Permeases of the major facilitator superf... 118 1e-26 RSp0052 [GEPR] COG0477 Permeases of the major facilitator superf... 117 3e-26 Ta0334 [GEPR] COG0477 Permeases of the major facilitator superfa... 115 1e-25 >PA3467 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 455 Score = 128 bits (322), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 89/256 (34%), Positives = 136/256 (53%), Gaps = 18/256 (7%) Query: 1 MPLSAAASLPARLDRLPWSRWHWRVVIALGVAWVLDGLEVT----LVGSIGSVLERPDTL 56 MP A AS RL+RLP S +H V + + +A+ D +++ L+GSI + Sbjct: 1 MP-DAPASAAERLERLPLSPYHRLVFVIIALAFFFDSMDLAMMTFLLGSIKA------EF 53 Query: 57 GLDAAQVGWTGSLYIAGAVVGALVFGRLTDRLGRKKLFMITLALYMAATLASAFATDFLW 116 GLD+AQ G S G V+GA + G L DR GRK +F ++ L+ A+ + A D Sbjct: 54 GLDSAQAGLLASSSFFGMVIGAALSGMLADRFGRKPVFQASIVLWGLASYLCSTAGDLDS 113 Query: 117 FALCRLATGLGIGGEYAAINSAIDELVPARVRGRVNLVINASFWIGAALGAGLSLVILDE 176 R+ G+G+G E+ S + E++PA RG+ +++ + +G LS +L Sbjct: 114 LTFYRVLLGIGMGMEFPIAQSLLSEMIPASRRGKYIALMDGFWPLGFVAAGCLSYFLL-- 171 Query: 177 RVLGPVMGWRVCFLLGAVLAVAIVLVRRHVPESPRWLAMHGHHARAEAVVREIEAQVMAE 236 P+ GWR FL+ A+ AV ++ +R +PESPRWL G +A+ V+R+IEA+VM Sbjct: 172 ----PLTGWRSIFLVLALPAVFVLAIRFLIPESPRWLEQAGRREQADRVLRDIEARVMRS 227 Query: 237 HGTLPALPTAAXRPAR 252 G L LP +P R Sbjct: 228 LG-LTELPPPLRQPQR 242 >PAE2330 [GEPR] COG0477 Permeases of the major facilitator superfamily Pya Pyrobaculum aerophilum Length = 384 Score = 119 bits (298), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 73/197 (37%), Positives = 109/197 (55%), Gaps = 10/197 (5%) Query: 24 RVVIALGVAWVLDGLEVTLVGSIGSVLERPDTLGLDAAQVGWTGSLYIAGAVVGALVFGR 83 R+V+ G+ W+ D L+V ++ + ++ + L LD+ W G ++GA++FGR Sbjct: 5 RLVLYTGLGWMFDALDVLILSYL--LVAMSNELKLDSQAKNWIVLANNLGMLIGAMLFGR 62 Query: 84 LTDRLGRKKLFMITLALYMAATLASAFATDFLWFALCRLATGLGIGGEYAAINSAIDELV 143 L DR+GRKK+FM TL Y AT SAFA ++ FA+ R GLG+GGE + + + E Sbjct: 63 LADRVGRKKVFMSTLLTYSIATAISAFARNWQEFAVIRFFVGLGLGGELPVVATYVSENS 122 Query: 144 PARVRGRVNLVINASFW-IGAALGAGLSLVILDERVLGPVMGWRVCFLLGAVLAVAIVLV 202 P RGR N+V+ SFW +GA L A +SL + +GWR LL A + ++ Sbjct: 123 PPERRGR-NVVLLESFWSLGAILAAAISLFLFT------TIGWRSSLLLMGATAFYVFVI 175 Query: 203 RRHVPESPRWLAMHGHH 219 R +PES RWL + Sbjct: 176 RFTLPESQRWLELREQR 192 >TVN0436 [GEPR] COG0477 Permeases of the major facilitator superfamily Tvo Thermoplasma volcanium Length = 445 Score = 118 bits (296), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 66/220 (30%), Positives = 114/220 (51%), Gaps = 7/220 (3%) Query: 13 LDRLPWSRWHWRVVIALGVAWVLDGLEVTLVGSIGSVLERPDTLGLDAAQVGWTGSLYIA 72 +DR+ +H ++ I + LDG +++++ ++L P L Sbjct: 7 MDRMGIRPFHRKIEILASMGMFLDGYDLSVITM--AILLMPTQLHFGKLDYILVNVSAFI 64 Query: 73 GAVVGALVFGRLTDRLGRKKLFMITLALYMAATLASAFATDFLWFALCRLATGLGIGGEY 132 G ++GA + GRL+DR+GRKK+F I L L++ + + AT+F + RL G+GIGG+Y Sbjct: 65 GMIIGAPLLGRLSDRIGRKKIFGIDLLLFVVFAITAGLATNFAMLFISRLMLGIGIGGDY 124 Query: 133 AAINSAIDELVPARVRGRVNLVINASFWIGAALGAGLSLVILDERVLGPVMGWRVCFLLG 192 ++ + E P RG + + +W+G+ A ++ P WR F++G Sbjct: 125 PISSTMVSEFSPVSKRGTLLYGMVGMYWLGSFFSAVMNYTF----AFTPYF-WRYTFIVG 179 Query: 193 AVLAVAIVLVRRHVPESPRWLAMHGHHARAEAVVREIEAQ 232 V+A+ I+ +R +PESPRWL HG AE+VV ++ + Sbjct: 180 GVIAIPIIFLRMRIPESPRWLIGHGMTKSAESVVEDLTGR 219 >RSp0052 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 476 Score = 117 bits (293), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 91/256 (35%), Positives = 139/256 (54%), Gaps = 13/256 (5%) Query: 1 MPLSAAASLPARLDRLPWSRWHWRVVIALGVAWVLDGLEV-TLVGSIGSVLERPDTLGLD 59 P +A A+ ARL+RLP+S +H R+ I + +A+ D +++ T+ +GS+ + GL Sbjct: 5 FPAAAQANAAARLERLPFSGYHKRIFIIIAIAFFFDSVDLATMTFVLGSIKKE---FGLS 61 Query: 60 AAQVGWTGSLYIAGAVVGALVFGRLTDRLGRKKLFMITLALYMAATLASAFATDFLWFAL 119 A G S G V+GA V G L DR GR+ +F ++ L+ A+ + A Sbjct: 62 TATAGLVASSSFFGMVIGAAVAGLLADRFGRRPVFQWSMVLWGVASYLCSTAQSVEALIA 121 Query: 120 CRLATGLGIGGEYAAINSAIDELVPARVRGRVNLVINASFWIGAALGAGLSLVILDERVL 179 R+ G+G+G E+ + + E VP RGR+ +++ FW + AG I+ VL Sbjct: 122 WRILLGIGMGMEFPVAQTLLSEFVPTANRGRLIALMDG-FWPLGFITAG----IVSYFVL 176 Query: 180 GPVMGWRVCFLLGAVLAVAIVLVRRHVPESPRWLAMHGHHARAEAVVREIEAQVMAEHGT 239 P GWR F L AV A+ +++VRR VPESPRWL G +A+A+ V+R IEA+VM T Sbjct: 177 -PQFGWRAVFALLAVPAIFVLIVRRAVPESPRWLEHAGRNAQADTVMRGIEAKVMRSLNT 235 Query: 240 L---PALPTAAXRPAR 252 P + +A +P R Sbjct: 236 TTLPPIVQHSAPQPVR 251 >Ta0334 [GEPR] COG0477 Permeases of the major facilitator superfamily Tac Thermoplasma acidophilum Length = 445 Score = 115 bits (288), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 62/221 (28%), Positives = 111/221 (50%), Gaps = 7/221 (3%) Query: 12 RLDRLPWSRWHWRVVIALGVAWVLDGLEVTLVGSIGSVLERPDTLGLDAAQVGWTGSLYI 71 +D + +H ++ I + LDG +++++ ++L P L + + Sbjct: 6 EMDNMRMRPFHRKMEILASMGMFLDGYDLSVIAM--AILLMPIQLKFSKPEYILVNVSAL 63 Query: 72 AGAVVGALVFGRLTDRLGRKKLFMITLALYMAATLASAFATDFLWFALCRLATGLGIGGE 131 AG +VGA + GRL+DR+GRKK+F I L L++ + + AT+F + R G+GIGG+ Sbjct: 64 AGMIVGAPLLGRLSDRIGRKKIFDIDLILFVVFAITAGLATNFWMMFISRFMLGVGIGGD 123 Query: 132 YAAINSAIDELVPARVRGRVNLVINASFWIGAALGAGLSLVILDERVLGPVMGWRVCFLL 191 Y ++ + E P + RG + + +W+G+ I++ WR F++ Sbjct: 124 YPISSTIVSEFAPVKRRGTLLYAMVGMYWLGSLFSG-----IMNYTFAFTYYFWRYTFII 178 Query: 192 GAVLAVAIVLVRRHVPESPRWLAMHGHHARAEAVVREIEAQ 232 G ++A+ I+ +R +PESPRWL G A V+ I + Sbjct: 179 GGIVAIPIISLRMQIPESPRWLVSQGRADEASKVIENITGK 219