BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0042.0146.p (295 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGl2015 [K] COG0583 Transcriptional regulator Atu Agrobacterium ... 343 2e-94 PA3587 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 242 9e-64 VC1706 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae 239 5e-63 metR [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 218 1e-56 ZmetR [K] COG0583 Transcriptional regulator EcZ Escherichia coli... 218 1e-56 >AGl2015 [K] COG0583 Transcriptional regulator Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 295 Score = 343 bits (881), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 160/295 (54%), Positives = 218/295 (73%) Query: 1 MLDRIHLSIVQEVERQGSLTAAAGVLHVTQSALSHSMKKLEQQLGTDIWLREGRHLRLTQ 60 MLDR HLSI++EV+R GSLTAAA L+V+QSALSH+++KLE + G +W ++GR+LRLT Sbjct: 1 MLDRQHLSILREVDRMGSLTAAAERLNVSQSALSHTIRKLEDRYGVAMWEKDGRNLRLTD 60 Query: 61 AGQYLLAVANRVLPQLSLAEERLRQFAQGERGALRIGMECHPCYQWLLKVVSPYLAAWPD 120 AG+Y+L +A RVLPQ+ AE L + G+RG+L+IGMECHPC+QWL+ V PYL WPD Sbjct: 61 AGRYILTLAQRVLPQIERAENVLSDYRHGQRGSLKIGMECHPCHQWLMSVTKPYLMEWPD 120 Query: 121 VDVDVKQKFQFGGIGALFGYEIDLLVTPDPLDKPGLVFEPVFDYEQVLVVASDHPLADAD 180 V +++ F FGG+ AL GYEID+L+TPDP++ G+ + PVFDYE VL V DHPLA Sbjct: 121 VGLELTTSFAFGGVAALAGYEIDILITPDPIEMAGVHYLPVFDYELVLAVPVDHPLALKR 180 Query: 181 YVKPKQLSNEVLVTYPVPVDRLDIYTQFLAPAGIVPRRHKTIETTDIMLQMVASGRGVAA 240 + +P L +E L TYPVP +RLD+++QFL PA PR H+ IETT++MLQ+VA+GRGV+A Sbjct: 181 HAEPADLLDETLFTYPVPPERLDVFSQFLVPANCRPRHHRNIETTEMMLQLVAAGRGVSA 240 Query: 241 LPRWLVLEYAEQMEVVPVRLGKQGIAKHIYLGARESDVEIDYLRAFIDEARQAQA 295 +P WLV A + V VR+G+ GI K I+LG R+ D +D++ F++ +RQ A Sbjct: 241 IPDWLVRREAAALGVRAVRIGQSGIQKSIHLGLRDGDDTVDFIAGFLETSRQILA 295 >PA3587 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 306 Score = 242 bits (617), Expect = 9e-64, Method: Compositional matrix adjust. Identities = 120/291 (41%), Positives = 182/291 (62%) Query: 1 MLDRIHLSIVQEVERQGSLTAAAGVLHVTQSALSHSMKKLEQQLGTDIWLREGRHLRLTQ 60 ML+ HL + + SL AA LH+TQSALSH K+LE++LG +++R+ + +R T Sbjct: 1 MLELRHLKTLHALREADSLVEAAERLHLTQSALSHQFKELEERLGMQLFVRKTKPVRFTS 60 Query: 61 AGQYLLAVANRVLPQLSLAEERLRQFAQGERGALRIGMECHPCYQWLLKVVSPYLAAWPD 120 AG LL +A+ +LPQL AE L + A G G L + +ECH C+QWL+ + + AWP+ Sbjct: 61 AGLRLLQLADSLLPQLRTAERDLARLAGGTAGRLHMAIECHSCFQWLMPTIDQFRDAWPE 120 Query: 121 VDVDVKQKFQFGGIGALFGYEIDLLVTPDPLDKPGLVFEPVFDYEQVLVVASDHPLADAD 180 V++D+ F F + AL ++DL+VT DP++ PG+ + P+F YE +L VA+ H LA Sbjct: 121 VELDLASGFSFAPLPALARGDLDLVVTADPVELPGITYVPLFTYEALLAVANQHALAGRP 180 Query: 181 YVKPKQLSNEVLVTYPVPVDRLDIYTQFLAPAGIVPRRHKTIETTDIMLQMVASGRGVAA 240 YV P+ L E L+TYPV DRLD++T+FL PA + P + + E T +M+Q+VASGRGV Sbjct: 181 YVVPEDLERETLITYPVERDRLDVFTRFLDPADVEPAQVRIAELTVMMMQLVASGRGVCC 240 Query: 241 LPRWLVLEYAEQMEVVPVRLGKQGIAKHIYLGARESDVEIDYLRAFIDEAR 291 LP W + EY+ + V RLG++G+ ++ R + ++R F+ A+ Sbjct: 241 LPNWALHEYSSRGYVTARRLGEKGLYCTLFAAIRTDMFDAPFMRDFLLTAK 291 >VC1706 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae Length = 305 Score = 239 bits (611), Expect = 5e-63, Method: Compositional matrix adjust. Identities = 117/292 (40%), Positives = 183/292 (62%), Gaps = 1/292 (0%) Query: 1 MLDRIHLSIVQEVERQGSLTAAAGVLHVTQSALSHSMKKLEQQLGTDIWLREGRHLRLTQ 60 M++ HL + + GSLTA A LH+TQSALSH +K LE ++G ++LR+ R +R T Sbjct: 1 MIELKHLKTLISLRDTGSLTATATSLHLTQSALSHQIKDLEARIGGQLFLRKTRPVRFTA 60 Query: 61 AGQYLLAVANRVLPQLSLAEERLRQFAQGERGALRIGMECHPCYQWLLKVVSPYLAAWPD 120 G+ LL +A+ +LP++S AE L + G L + +ECH C+QWL+ + Y +WP+ Sbjct: 61 EGEILLRLADDILPKMSRAENELASLKEDVNGRLHMAIECHSCFQWLMPALREYQVSWPN 120 Query: 121 VDVDVKQKFQFGGIGALFGYEIDLLVTPDPLDKPGLVFEPVFDYEQVLVVASDHPLADAD 180 V +D F F + AL E+DL++T D L + + +EP+FD+E L+ A++HPLAD Sbjct: 121 VALDFSSGFGFEPLPALLAGELDLVITSDILPRSEVHYEPLFDFEMRLITATNHPLADKA 180 Query: 181 YVKPKQLSNEVLVTYPVPVDRLDIYTQFLAPAGIVPRRHKTIETTDIMLQMVASGRGVAA 240 ++P+ L+++ ++TYPV RLD+ FL PAG+ P R K + T +++QMV++G GVAA Sbjct: 181 GIEPQDLADQTMLTYPVQKQRLDVVKHFLQPAGVEPARWKQADNTLMLVQMVSAGLGVAA 240 Query: 241 LPRWLVLEYAEQMEVVPVRLGKQGIAKHIYLGARESDVEIDYLRAFIDEARQ 292 LP W + E++ Q + LGK G+ + ++ R S+ + YL+AF ARQ Sbjct: 241 LPNWAISEFSRQGLITSKPLGK-GLWRRLFAATRHSEKDKRYLQAFFATARQ 291 >metR [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 Length = 317 Score = 218 bits (555), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 121/292 (41%), Positives = 174/292 (59%), Gaps = 5/292 (1%) Query: 1 MLDRIHLSIVQEVERQGSLTAAAGVLHVTQSALSHSMKKLEQQLGTDIWLREGRHLRLTQ 60 M++ HL +Q + GSL AAA LH TQSALSH LEQ+LG +++R+ + LR T Sbjct: 1 MIEVKHLKTLQALRNCGSLAAAAATLHQTQSALSHQFSDLEQRLGFRLFVRKSQPLRFTP 60 Query: 61 AGQYLLAVANRVLPQLSLAEERLRQFAQGERGALRIGMECHPCYQWLLKVVSPYLAAWPD 120 G+ LL +AN+VLPQ+S A L+ + ++ LRI +ECH C QWL + + WP Sbjct: 61 QGEILLQLANQVLPQISQA---LQACNEPQQTRLRIAIECHSCIQWLTPALENFHKNWPQ 117 Query: 121 VDVDVKQKFQFGGIGALFGYEIDLLVTPDPLDKPGLVFEPVFDYEQVLVVASDHPLADAD 180 V++D K F AL E+DL++T D L + GL + P+FDYE LV+A DHPLA Sbjct: 118 VEMDFKSGVTFDPQPALQQGELDLVMTSDILPRSGLHYSPMFDYEVRLVLAPDHPLAAKT 177 Query: 181 YVKPKQLSNEVLVTYPVPVDRLDIYTQFLAPAGIVPRRHKTIETTDIMLQMVASGRGVAA 240 + P+ L++E L+ YPV RLD++ FL PAG+ P K+++ T +++QMVA+ G+AA Sbjct: 178 RITPEDLASETLLIYPVQRSRLDVWRHFLQPAGVSPSL-KSVDNTLLLIQMVAARMGIAA 236 Query: 241 LPRWLVLEYAEQMEVVPVRLGKQGIAKHIYLGARESDVEIDYLRAFIDEARQ 292 LP W+V + Q VV LG +G+ +Y R+ + AFI AR Sbjct: 237 LPHWVVESFERQGLVVTKTLG-EGLWSRLYAAVRDGEQRQPVTEAFIRSARN 287 >ZmetR [K] COG0583 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 317 Score = 218 bits (555), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 121/292 (41%), Positives = 174/292 (59%), Gaps = 5/292 (1%) Query: 1 MLDRIHLSIVQEVERQGSLTAAAGVLHVTQSALSHSMKKLEQQLGTDIWLREGRHLRLTQ 60 M++ HL +Q + GSL AAA LH TQSALSH LEQ+LG +++R+ + LR T Sbjct: 1 MIEVKHLKTLQALRNCGSLAAAAATLHQTQSALSHQFSDLEQRLGFRLFVRKSQPLRFTP 60 Query: 61 AGQYLLAVANRVLPQLSLAEERLRQFAQGERGALRIGMECHPCYQWLLKVVSPYLAAWPD 120 G+ LL +AN+VLPQ+S A L+ + ++ LRI +ECH C QWL + + WP Sbjct: 61 QGEILLQLANQVLPQISQA---LQACNEPQQTRLRIAIECHSCIQWLTPALENFHKNWPQ 117 Query: 121 VDVDVKQKFQFGGIGALFGYEIDLLVTPDPLDKPGLVFEPVFDYEQVLVVASDHPLADAD 180 V++D K F AL E+DL++T D L + GL + P+FDYE LV+A DHPLA Sbjct: 118 VEMDFKSGVTFDPQPALQQGELDLVMTSDILPRSGLHYSPMFDYEVRLVLAPDHPLAAKT 177 Query: 181 YVKPKQLSNEVLVTYPVPVDRLDIYTQFLAPAGIVPRRHKTIETTDIMLQMVASGRGVAA 240 + P+ L++E L+ YPV RLD++ FL PAG+ P K+++ T +++QMVA+ G+AA Sbjct: 178 RITPEDLASETLLIYPVQRSRLDVWRHFLQPAGVSPSL-KSVDNTLLLIQMVAARMGIAA 236 Query: 241 LPRWLVLEYAEQMEVVPVRLGKQGIAKHIYLGARESDVEIDYLRAFIDEARQ 292 LP W+V + Q VV LG +G+ +Y R+ + AFI AR Sbjct: 237 LPHWVVESFERQGLVVTKTLG-EGLWSRLYAAVRDGEQRQPVTEAFIRSARN 287