BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0042.0063.p (349 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value XF1746 [R] COG1064 Zn-dependent alcohol dehydrogenases Xfa Xylel... 585 e-167 XF2389 [R] COG1064 Zn-dependent alcohol dehydrogenases Xfa Xylel... 570 e-162 yahK [R] COG1064 Zn-dependent alcohol dehydrogenases Eco Escheri... 552 e-157 ZyahK [R] COG1064 Zn-dependent alcohol dehydrogenases EcZ Escher... 548 e-156 ECs0379 [R] COG1064 Zn-dependent alcohol dehydrogenases Ecs Esch... 548 e-156 >XF1746 [R] COG1064 Zn-dependent alcohol dehydrogenases Xfa Xylella fastidiosa 9a5c Length = 349 Score = 585 bits (1507), Expect = e-167, Method: Compositional matrix adjust. Identities = 298/349 (85%), Positives = 318/349 (91%) Query: 1 MQVHAYGAHAADKPLEHLHITRRATGAHDVQIDIAYCGICHSDLHQIRSEWAGTQYPCVP 60 M V AYGA+AADKPLE L ITRRA GAHDVQIDIAYCG+CHSDLHQ+R+EWAGTQ+PCVP Sbjct: 1 MTVKAYGAYAADKPLESLDITRRAPGAHDVQIDIAYCGVCHSDLHQVRAEWAGTQFPCVP 60 Query: 61 GHEIVGRVAAVGAHVSKFKVGDVVGVGCIVDSCQSCPDCDEGLENYCDNMVGTYNGKTDD 120 GHEIVGRV+AVGAHVS F+ GD+VG+GCIVDSC+ C DC EGLENYCD MVGTYNG T D Sbjct: 61 GHEIVGRVSAVGAHVSGFQPGDLVGIGCIVDSCKHCDDCAEGLENYCDEMVGTYNGPTPD 120 Query: 121 APGWTMGGYSQQIVVHERYVLNIRHPEADLAAVAPLLCAGITTYSPLRHWGAGPGKKVGV 180 APG T+GGYSQQIVVHERYVL IRH E+ LAAVAPLLCAGITTYSPLRHW AGPGKKVGV Sbjct: 121 APGHTLGGYSQQIVVHERYVLRIRHDESQLAAVAPLLCAGITTYSPLRHWNAGPGKKVGV 180 Query: 181 VGIGGLGHMGIKIAHAMGAHVVAFTTSDSKRADAKALGADEVVVSRNAEEMAAHAKSFDF 240 VGIGGLGHMGIK+AHAMGAHVVAFTTS+SKR A ALGADEVVVSRN EMAAH +SFDF Sbjct: 181 VGIGGLGHMGIKLAHAMGAHVVAFTTSESKRDAAMALGADEVVVSRNPGEMAAHGQSFDF 240 Query: 241 ILNTVAAPHDLDAFLALLKREGTMTLVGAPATPHPSPNVFNLILKRRSLAGSLIGGIPET 300 ILNTVAAPHDL+AF+ LLKR+GTMT VGAPA+PHPSP VFN ILKRRSLAGS IGGIPET Sbjct: 241 ILNTVAAPHDLNAFMTLLKRDGTMTPVGAPASPHPSPEVFNFILKRRSLAGSAIGGIPET 300 Query: 301 QEMLDFCAEHGIVADIELIRADEINTAYERMLKGDVKYRFVIDNASLAA 349 QEMLDFCAEH IVADIELIRA+EIN AYERMLKGDVKYRFVIDNASLAA Sbjct: 301 QEMLDFCAEHNIVADIELIRAEEINDAYERMLKGDVKYRFVIDNASLAA 349 >XF2389 [R] COG1064 Zn-dependent alcohol dehydrogenases Xfa Xylella fastidiosa 9a5c Length = 349 Score = 570 bits (1469), Expect = e-162, Method: Compositional matrix adjust. Identities = 281/349 (80%), Positives = 309/349 (88%) Query: 1 MQVHAYGAHAADKPLEHLHITRRATGAHDVQIDIAYCGICHSDLHQIRSEWAGTQYPCVP 60 M ++AYGAHA DKPLE + I RR GAHDVQIDI YCG+CHSD+HQ+RSEWAGT +PCVP Sbjct: 1 MFINAYGAHAGDKPLESMQIARRVPGAHDVQIDIHYCGVCHSDIHQVRSEWAGTLFPCVP 60 Query: 61 GHEIVGRVAAVGAHVSKFKVGDVVGVGCIVDSCQSCPDCDEGLENYCDNMVGTYNGKTDD 120 GHEIVGRV+A+G HV FK GD+V VGC+VDSC+ C +C+ GLENYCD M+GTYN T D Sbjct: 61 GHEIVGRVSAIGTHVKGFKTGDLVAVGCMVDSCKDCQECNAGLENYCDGMIGTYNFPTHD 120 Query: 121 APGWTMGGYSQQIVVHERYVLNIRHPEADLAAVAPLLCAGITTYSPLRHWGAGPGKKVGV 180 APG T+GGYSQ+IVV ERYVL IRHPEA LAAVAPLLCAGITTYSPLRHW AGPGKKVG+ Sbjct: 121 APGHTLGGYSQKIVVDERYVLRIRHPEAQLAAVAPLLCAGITTYSPLRHWNAGPGKKVGI 180 Query: 181 VGIGGLGHMGIKIAHAMGAHVVAFTTSDSKRADAKALGADEVVVSRNAEEMAAHAKSFDF 240 VGIGGLGHMGIK+AHAMGAHVVAFTTS+SKR DAKALGADEVVVSR+ E MAAH KSFD Sbjct: 181 VGIGGLGHMGIKLAHAMGAHVVAFTTSESKRQDAKALGADEVVVSRDEESMAAHVKSFDL 240 Query: 241 ILNTVAAPHDLDAFLALLKREGTMTLVGAPATPHPSPNVFNLILKRRSLAGSLIGGIPET 300 ILNTVAA H LD FL LLKR+GT+TLVGAPATPHPSP +FNLI KRRS+AGSLIGGI ET Sbjct: 241 ILNTVAASHSLDPFLTLLKRDGTLTLVGAPATPHPSPQIFNLIFKRRSIAGSLIGGIAET 300 Query: 301 QEMLDFCAEHGIVADIELIRADEINTAYERMLKGDVKYRFVIDNASLAA 349 QEMLDFCAE+GIVADIELIRAD IN AYERM+KGDVKYRFVIDNA+LAA Sbjct: 301 QEMLDFCAENGIVADIELIRADGINEAYERMMKGDVKYRFVIDNATLAA 349 >yahK [R] COG1064 Zn-dependent alcohol dehydrogenases Eco Escherichia coli K12 Length = 349 Score = 552 bits (1422), Expect = e-157, Method: Compositional matrix adjust. Identities = 275/347 (79%), Positives = 309/347 (89%) Query: 1 MQVHAYGAHAADKPLEHLHITRRATGAHDVQIDIAYCGICHSDLHQIRSEWAGTQYPCVP 60 M++ A GA++A +PLE + ITRR G +DV+I+IAYCG+CHSDLHQ+RSEWAGT YPCVP Sbjct: 1 MKIKAVGAYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDLHQVRSEWAGTVYPCVP 60 Query: 61 GHEIVGRVAAVGAHVSKFKVGDVVGVGCIVDSCQSCPDCDEGLENYCDNMVGTYNGKTDD 120 GHEIVGRV AVG V K+ GD+VGVGCIVDSC+ C +C++GLENYCD+M GTYN T D Sbjct: 61 GHEIVGRVVAVGDQVEKYAPGDLVGVGCIVDSCKHCEECEDGLENYCDHMTGTYNSPTPD 120 Query: 121 APGWTMGGYSQQIVVHERYVLNIRHPEADLAAVAPLLCAGITTYSPLRHWGAGPGKKVGV 180 PG T+GGYSQQIVVHERYVL IRHP+ LAAVAPLLCAGITTYSPLRHW AGPGKKVGV Sbjct: 121 EPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAGITTYSPLRHWQAGPGKKVGV 180 Query: 181 VGIGGLGHMGIKIAHAMGAHVVAFTTSDSKRADAKALGADEVVVSRNAEEMAAHAKSFDF 240 VGIGGLGHMGIK+AHAMGAHVVAFTTS++KR AKALGADEVV SRNA+EMAAH KSFDF Sbjct: 181 VGIGGLGHMGIKLAHAMGAHVVAFTTSEAKREAAKALGADEVVNSRNADEMAAHLKSFDF 240 Query: 241 ILNTVAAPHDLDAFLALLKREGTMTLVGAPATPHPSPNVFNLILKRRSLAGSLIGGIPET 300 ILNTVAAPH+LD F LLKR+GTMTLVGAPATPH SP VFNLI+KRR++AGS+IGGIPET Sbjct: 241 ILNTVAAPHNLDDFTTLLKRDGTMTLVGAPATPHKSPEVFNLIMKRRAIAGSMIGGIPET 300 Query: 301 QEMLDFCAEHGIVADIELIRADEINTAYERMLKGDVKYRFVIDNASL 347 QEMLDFCAEHGIVADIE+IRAD+IN AYERML+GDVKYRFVIDN +L Sbjct: 301 QEMLDFCAEHGIVADIEMIRADQINEAYERMLRGDVKYRFVIDNRTL 347 >ZyahK [R] COG1064 Zn-dependent alcohol dehydrogenases EcZ Escherichia coli O157:H7 EDL933 Length = 349 Score = 548 bits (1413), Expect = e-156, Method: Compositional matrix adjust. Identities = 274/347 (78%), Positives = 308/347 (88%) Query: 1 MQVHAYGAHAADKPLEHLHITRRATGAHDVQIDIAYCGICHSDLHQIRSEWAGTQYPCVP 60 M++ A G+++A +PLE + ITRR G +DV+I+IAYCG+CHSDLHQ+RSEWAGT YPCVP Sbjct: 1 MKIKAVGSYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDLHQVRSEWAGTVYPCVP 60 Query: 61 GHEIVGRVAAVGAHVSKFKVGDVVGVGCIVDSCQSCPDCDEGLENYCDNMVGTYNGKTDD 120 GHEIVGRV AVG V K GD+VGVGCIVDSC+ C +C++GLENYCD+M GTYN T D Sbjct: 61 GHEIVGRVVAVGDQVEKHAPGDLVGVGCIVDSCKHCEECEDGLENYCDHMTGTYNSPTPD 120 Query: 121 APGWTMGGYSQQIVVHERYVLNIRHPEADLAAVAPLLCAGITTYSPLRHWGAGPGKKVGV 180 PG T+GGYSQQIVVHERYVL IRHP+ LAAVAPLLCAGITTYSPLRHW AGPGKKVGV Sbjct: 121 EPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAGITTYSPLRHWQAGPGKKVGV 180 Query: 181 VGIGGLGHMGIKIAHAMGAHVVAFTTSDSKRADAKALGADEVVVSRNAEEMAAHAKSFDF 240 VGIGGLGHMGIK+AHAMGAHVVAFTTS++KR AKALGADEVV SRNA+EMAAH KSFDF Sbjct: 181 VGIGGLGHMGIKLAHAMGAHVVAFTTSEAKREAAKALGADEVVNSRNADEMAAHLKSFDF 240 Query: 241 ILNTVAAPHDLDAFLALLKREGTMTLVGAPATPHPSPNVFNLILKRRSLAGSLIGGIPET 300 ILNTVAAPH+LD F LLKR+GTMTLVGAPATPH SP VFNLI+KRR++AGS+IGGIPET Sbjct: 241 ILNTVAAPHNLDDFTTLLKRDGTMTLVGAPATPHKSPEVFNLIMKRRAIAGSMIGGIPET 300 Query: 301 QEMLDFCAEHGIVADIELIRADEINTAYERMLKGDVKYRFVIDNASL 347 QEMLDFCAEHGIVADIE+IRAD+IN AYERML+GDVKYRFVIDN +L Sbjct: 301 QEMLDFCAEHGIVADIEMIRADQINEAYERMLRGDVKYRFVIDNRTL 347 >ECs0379 [R] COG1064 Zn-dependent alcohol dehydrogenases Ecs Escherichia coli O157:H7 Length = 349 Score = 548 bits (1413), Expect = e-156, Method: Compositional matrix adjust. Identities = 274/347 (78%), Positives = 308/347 (88%) Query: 1 MQVHAYGAHAADKPLEHLHITRRATGAHDVQIDIAYCGICHSDLHQIRSEWAGTQYPCVP 60 M++ A G+++A +PLE + ITRR G +DV+I+IAYCG+CHSDLHQ+RSEWAGT YPCVP Sbjct: 1 MKIKAVGSYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDLHQVRSEWAGTVYPCVP 60 Query: 61 GHEIVGRVAAVGAHVSKFKVGDVVGVGCIVDSCQSCPDCDEGLENYCDNMVGTYNGKTDD 120 GHEIVGRV AVG V K GD+VGVGCIVDSC+ C +C++GLENYCD+M GTYN T D Sbjct: 61 GHEIVGRVVAVGDQVEKHAPGDLVGVGCIVDSCKHCEECEDGLENYCDHMTGTYNSPTPD 120 Query: 121 APGWTMGGYSQQIVVHERYVLNIRHPEADLAAVAPLLCAGITTYSPLRHWGAGPGKKVGV 180 PG T+GGYSQQIVVHERYVL IRHP+ LAAVAPLLCAGITTYSPLRHW AGPGKKVGV Sbjct: 121 EPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAGITTYSPLRHWQAGPGKKVGV 180 Query: 181 VGIGGLGHMGIKIAHAMGAHVVAFTTSDSKRADAKALGADEVVVSRNAEEMAAHAKSFDF 240 VGIGGLGHMGIK+AHAMGAHVVAFTTS++KR AKALGADEVV SRNA+EMAAH KSFDF Sbjct: 181 VGIGGLGHMGIKLAHAMGAHVVAFTTSEAKREAAKALGADEVVNSRNADEMAAHLKSFDF 240 Query: 241 ILNTVAAPHDLDAFLALLKREGTMTLVGAPATPHPSPNVFNLILKRRSLAGSLIGGIPET 300 ILNTVAAPH+LD F LLKR+GTMTLVGAPATPH SP VFNLI+KRR++AGS+IGGIPET Sbjct: 241 ILNTVAAPHNLDDFTTLLKRDGTMTLVGAPATPHKSPEVFNLIMKRRAIAGSMIGGIPET 300 Query: 301 QEMLDFCAEHGIVADIELIRADEINTAYERMLKGDVKYRFVIDNASL 347 QEMLDFCAEHGIVADIE+IRAD+IN AYERML+GDVKYRFVIDN +L Sbjct: 301 QEMLDFCAEHGIVADIEMIRADQINEAYERMLRGDVKYRFVIDNRTL 347