BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0042.0026.p (344 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO2237 [GEPR] COG0477 Permeases of the major facilitator superf... 218 1e-56 STM1107 [GEPR] COG0477 Permeases of the major facilitator superf... 216 5e-56 RSp0182 [GEPR] COG0477 Permeases of the major facilitator superf... 214 3e-55 YPO1768 [GEPR] COG0477 Permeases of the major facilitator superf... 211 2e-54 AGc4908 [GEPR] COG0477 Permeases of the major facilitator superf... 206 6e-53 >YPO2237 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 436 Score = 218 bits (556), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 132/330 (40%), Positives = 201/330 (60%), Gaps = 8/330 (2%) Query: 1 MISWGLISMATAFVVGPKSFALARFLLGMAEAGFTPGIYLYFTQWFPGAWRGKATAFFLI 60 MI+WG+IS AFV P SF + RFLLG+AEAGF PGI LY + WFP RG+ F+I Sbjct: 100 MITWGIISACMAFVTTPMSFYVMRFLLGVAEAGFFPGIILYISYWFPSHRRGRVYGLFVI 159 Query: 61 GIPVANIIGSPLSGALME-LHGMWGFKGWQVLLLLEALPAVLLGVMCLFLLPDRPAKAKW 119 +P++ IIG+PLSG +M+ +G G+ GWQ + +LE +P+VL+G++ ++ L DR A W Sbjct: 160 SVPLSGIIGAPLSGWIMQYFNGFQGYAGWQWMFILEGIPSVLVGILIIYKLKDRITHATW 219 Query: 120 LSADEKQWLENELSTEQNVLAARHGN-KLKDAFTNWRVFALAGANFCGIIGSLSIGLWLP 178 L+ EK L+ + E AA + + +L+DAF RV+ L FC I G +IG WLP Sbjct: 220 LTDKEKDILQTNIENE----AAHYAHSRLRDAFLQPRVWLLTLIYFCLISGFYTIGFWLP 275 Query: 179 QIIREFGLPS-HQVGLVAAVPYLVGAVAMTLWARLANRSERRLFFVAGAIVLAALSLGVS 237 +IR+ G+ +G + A+P AV M + +R A+R R + +A VL A+ + +S Sbjct: 276 TLIRDSGVKDILSIGFLTAIPSAAAAVTMIVVSRSADRLRERRWHLALTAVLGAVGIILS 335 Query: 238 AFLHTPL-LKMLAITVAVASILSFQATFWAIPSGFLTGRAAAGGLALIVSIGNLGGFVGP 296 + + + M+ +T+ LS FW++P+ FL G AAA G+A I S GNLGGFV P Sbjct: 336 TYFSDNIVVAMVCLTIGAMGALSTIPLFWSLPTAFLGGSAAAAGIAFINSWGNLGGFVAP 395 Query: 297 SVIGFIREATQGFTYPLIFVAGALLLGAVI 326 ++G++++ TQ T ++ ++ L +GA + Sbjct: 396 YMMGYLKDLTQSTTTGMLIISTTLFIGAAL 425 >STM1107 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 458 Score = 216 bits (550), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 125/337 (37%), Positives = 189/337 (56%), Gaps = 11/337 (3%) Query: 1 MISWGLISMATAFVVGPKSFALARFLLGMAEAGFTPGIYLYFTQWFPGAWRGKATAFFLI 60 M+ WG+ S AT F VGPKS + R L+G+ EAGF PGI LY T WFP +R +A A F+I Sbjct: 107 MVLWGIASTATMFAVGPKSLYVLRMLVGITEAGFLPGILLYLTYWFPAFFRARANALFMI 166 Query: 61 GIPVANIIGSPLSGALMELHGMWGFKGWQVLLLLEALPAVLLGVMCLFLLPDRPAKAKWL 120 +P +GS +SG ++ L G++ GWQ L LLE P+VLLG+M F L D PAKAKWL Sbjct: 167 AMPATTALGSIVSGYILSLDGIFNLHGWQWLFLLEGFPSVLLGIMVWFYLDDTPAKAKWL 226 Query: 121 SADEKQWLENELSTEQNVLAARHGNKLKDAFTN---WR------VFALAGANFCGIIGSL 171 +A++K+ L+ + +++ L G +A WR V A FC Sbjct: 227 TAEDKKCLQEMMDSDRLTLVQPEGAISHNAMQQRSLWREVFTPIVLMYTLAYFCLTNTLS 286 Query: 172 SIGLWLPQIIREF--GLPSHQVGLVAAVPYLVGAVAMTLWARLANRSERRLFFVAGAIVL 229 +I +W PQI++ F G + +GL+AA+P + + M W+R +++ + R A + Sbjct: 287 AISIWTPQILKSFNEGSSNITIGLLAAIPQICTILGMIYWSRHSDKHQERKHHTALPFLF 346 Query: 230 AALSLGVSAFLHTPLLKMLAITVAVASILSFQATFWAIPSGFLTGRAAAGGLALIVSIGN 289 AA +++ L+++L I +A S A FW P ++ RA A G+A+I + GN Sbjct: 347 AAAGWLLASATDHNLIQLLGIVMASTGSFSAMAIFWTTPDQSISLRARAIGIAVINATGN 406 Query: 290 LGGFVGPSVIGFIREATQGFTYPLIFVAGALLLGAVI 326 +G + P +IG++++ T F L FVA L++GA I Sbjct: 407 IGSALSPFMIGWLKDITGSFNSGLWFVASLLVVGAAI 443 >RSp0182 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 453 Score = 214 bits (544), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 139/335 (41%), Positives = 200/335 (59%), Gaps = 8/335 (2%) Query: 1 MISWGLISMATAFVVGPKSFALARFLLGMAEAGFTPGIYLYFTQWFPGAWRGKATAFFLI 60 +++WGL++M +AFV RFLLG+AEAGF PGI +Y T WF A F Sbjct: 108 LVTWGLVAMGSAFVQSATQLYALRFLLGVAEAGFFPGIIVYLTYWFRARELATTVALFTA 167 Query: 61 GIPVANIIGSPLSGALMELHGMW-GFKGWQVLLLLEALPAVLLGVMCLFLLPDRPAKAKW 119 IPV+ ++G+PLS +M+ H W + GW+ +LLLE PAV+ G++C L DRP A+W Sbjct: 168 AIPVSYVVGAPLSTWIMD-HVHWLQWSGWRWMLLLEGAPAVIGGLLCYGYLADRPKDARW 226 Query: 120 LSADEKQWLENELSTEQNVL-AARHGNKLKDAFTNWRVFALAGANFCGIIGSLSIGLWLP 178 LS E+ WL EL ++ AA H LK T+ RV LA F GSL IG W+P Sbjct: 227 LSEAERDWLLAELERDRKARPAAAHLATLK-VMTHPRVLYLAFIYFVYQCGSLGIGYWMP 285 Query: 179 QIIREF--GLPSHQVGLVAAVPYLVGAVAMTLWARLAN-RSERRLFFVAGAIVLAALSLG 235 QII+ F L +VGL+A +PY+ M W+R ++ R+ERRL A + +AAL+ Sbjct: 286 QIIKGFSSALSHTEVGLIAMLPYVFATAVMIWWSRRSDLRAERRL-HSAVPLGVAALAFV 344 Query: 236 VSAFLHTPLLKMLAITVAVASILSFQATFWAIPSGFLTGRAAAGGLALIVSIGNLGGFVG 295 + F+ P + M +++++A + +F++ FWA+P+ FLT AA +A+I S+GNLGGFVG Sbjct: 345 GAGFIGHPAVAMAMLSLSLAGLYAFKSPFWALPTLFLTRSTAAVSIAVINSVGNLGGFVG 404 Query: 296 PSVIGFIREATQGFTYPLIFVAGALLLGAVITLAL 330 P IG+ + T L+F+AG L + V+TL L Sbjct: 405 PFAIGYFKGQMHSTTAGLLFLAGLLAVSFVMTLRL 439 >YPO1768 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 455 Score = 211 bits (537), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 123/348 (35%), Positives = 189/348 (54%), Gaps = 9/348 (2%) Query: 1 MISWGLISMATAFVVGPKSFALARFLLGMAEAGFTPGIYLYFTQWFPGAWRGKATAFFLI 60 M+ WG+ S AT F VGP S L R ++G+ EAGF PGI +Y T WFP +R +A A F++ Sbjct: 107 MVLWGIASTATLFAVGPNSLYLLRMIVGITEAGFLPGILVYLTYWFPAHFRARANALFMV 166 Query: 61 GIPVANIIGSPLSGALMELHGMWGFKGWQVLLLLEALPAVLLGVMCLFLLPDRPAKAKWL 120 +PV +GS +SG ++ L G +GWQ L LLE P+VLLG + F L D P KA+WL Sbjct: 167 AMPVTMALGSLVSGYILALDGFLNMRGWQWLFLLEGFPSVLLGGVVWFYLDDTPQKARWL 226 Query: 121 SADEKQWLENELSTEQNVLAARHGNKLKDAFTNWR------VFALAGANFCGIIGSLSIG 174 + ++KQ L+ L +++ LA + WR V A FC ++ Sbjct: 227 TKEDKQCLQEMLESDRLQLAKQADYGALPQSAMWREIFTPVVLMYTLAYFCLTNTLSAVN 286 Query: 175 LWLPQIIREFGLPSHQ--VGLVAAVPYLVGAVAMTLWARLANRSERRLFFVAGAIVLAAL 232 +W PQI++ F S +GL+AA+P + M W+R ++R + R + AA Sbjct: 287 IWTPQILQSFNQSSSNITIGLLAAIPQVCTIAGMIWWSRRSDRVQERKMHTVLPYLFAAA 346 Query: 233 SLGVSAFLHTPLLKMLAITVAVASILSFQATFWAIPSGFLTGRAAAGGLALIVSIGNLGG 292 +++ ++++L I +A + A FW P ++ RA A G+A+I + GN+G Sbjct: 347 GWVLASATQNSVIQLLGIIMASTGSFTAMAIFWTTPDQSISLRARAVGIAVINATGNIGS 406 Query: 293 FVGPSVIGFIREATQGFTYPLIFVAGALLLGAVITLALGDPSRVPPTS 340 V P +IG++++ T F L FVAG L++GAVI L + + PP + Sbjct: 407 AVSPVLIGWLKDQTGNFNSGLYFVAGLLVIGAVIFLMI-PMKKAPPKA 453 >AGc4908 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 487 Score = 206 bits (524), Expect = 6e-53, Method: Compositional matrix adjust. Identities = 117/328 (35%), Positives = 188/328 (57%), Gaps = 1/328 (0%) Query: 1 MISWGLISMATAFVVGPKSFALARFLLGMAEAGFTPGIYLYFTQWFPGAWRGKATAFFLI 60 ++SWG +++A A+ F + RFLLG+ EAGF PG+ T WFP +RG+ F+I Sbjct: 148 LVSWGAVTIALAYTQNATMFYILRFLLGLCEAGFFPGVLFLMTLWFPRDYRGRMIGLFMI 207 Query: 61 GIPVANIIGSPLSGALMELHGMWGFKGWQVLLLLEALPAVLLGVMCLFLLPDRPAKAKWL 120 +AN +G+PL G L++L G G+ GW+ + L +PAV+ G++ F L D P KAK+L Sbjct: 208 FSALANAVGAPLGGMLLDLDGFLGYAGWEWVFLATGIPAVIAGIVTFFYLDDTPDKAKFL 267 Query: 121 SADEKQWLENELSTEQNVLAARHGNKLKDAFTNWRVFALAGANFCGIIGSLSIGLWLPQI 180 + DEK WL+N L+ E+N H A N RV +A + + + WLP I Sbjct: 268 TQDEKDWLKNRLA-EENKGMEEHAEDGFKALVNPRVLFMALCYVGFPLAAYGLSYWLPTI 326 Query: 181 IREFGLPSHQVGLVAAVPYLVGAVAMTLWARLANRSERRLFFVAGAIVLAALSLGVSAFL 240 ++ FG+ + G + +P+++ A+A+ + A++++ + ++ G + A L +SA L Sbjct: 327 VKSFGVSNTTNGFINIIPWIIVAIALFVVPSAADKAKNKTPYIVGPAFVGAFCLLMSALL 386 Query: 241 HTPLLKMLAITVAVASILSFQATFWAIPSGFLTGRAAAGGLALIVSIGNLGGFVGPSVIG 300 P+L+ + VA A I + Q FW++P FL G AA G+A I S+GNLGGFV +V+ Sbjct: 387 SDPVLQFAFLCVAAAGIFAGQPVFWSLPGRFLKGAGAAAGIAAINSVGNLGGFVAQNVVP 446 Query: 301 FIREATQGFTYPLIFVAGALLLGAVITL 328 +I++ T P+ F+A L L V+ + Sbjct: 447 WIKDQTGSTIAPMFFLAFCLALAGVLVI 474