BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0042.0022.p (431 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0182 [GEPR] COG0477 Permeases of the major facilitator superf... 338 1e-92 STM1107 [GEPR] COG0477 Permeases of the major facilitator superf... 319 9e-87 RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 306 5e-83 BMEII1096 [GEPR] COG0477 Permeases of the major facilitator supe... 302 1e-81 YPO2237 [GEPR] COG0477 Permeases of the major facilitator superf... 300 5e-81 >RSp0182 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 453 Score = 338 bits (868), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 168/378 (44%), Positives = 239/378 (63%), Gaps = 6/378 (1%) Query: 11 EQETVRKVTWRLLPFLMLCYLFAFIDRGNIGMAALQMNHDLGLSPKMFGFASSLFFIAYF 70 E+ VRK+TWR+LPF+ Y+ +++DR NIG AALQMN +L LS + FGF S +FFI YF Sbjct: 26 ERAIVRKITWRILPFVFALYIISYLDRANIGYAALQMNQELALSSEAFGFVSGIFFIGYF 85 Query: 71 IFEVPSNLALQKFGARKWLARIMITWGLVSACTALVQGPNSLYFVRFILGAAEAGFFPGV 130 +FEVPSNL L +FGAR+W+ARI++TWGLV+ +A VQ LY +RF+LG AEAGFFPG+ Sbjct: 86 LFEVPSNLMLNRFGARRWIARILVTWGLVAMGSAFVQSATQLYALRFLLGVAEAGFFPGI 145 Query: 131 VLYLTYWVPSTYRARIVALFMVAIPAASFVASPVSALLLQMDGIGGLR--GWHWLFMLEG 188 ++YLTYW + A VALF AIP + V +P+S + MD + L+ GW W+ +LEG Sbjct: 146 IVYLTYWFRARELATTVALFTAAIPVSYVVGAPLSTWI--MDHVHWLQWSGWRWMLLLEG 203 Query: 189 LPTVVLGLVCLSFLTDRPDQARWLSDEQRQWLTETMNKEAASRAAKQHIPLWKLFSQPHV 248 P V+ GL+C +L DRP ARWLS+ +R WL + ++ +R A H+ K+ + P V Sbjct: 204 APAVIGGLLCYGYLADRPKDARWLSEAERDWLLAELERDRKARPAAAHLATLKVMTHPRV 263 Query: 249 WGMALVCACASAAGSVLNVWQPQLLKSF--GLSVMQTGLVNSIPYLIASVLMVWWGRHSD 306 +A + + W PQ++K F LS + GL+ +PY+ A+ +M+WW R SD Sbjct: 264 LYLAFIYFVYQCGSLGIGYWMPQIIKGFSSALSHTEVGLIAMLPYVFATAVMIWWSRRSD 323 Query: 307 RTGERRWHTAIPLMLIGGGLALASLAHSLAPVVLLLTMVLIGAYSFKGPFWAMASSWLAT 366 ERR H+A+PL + A A + +L++ L G Y+FK PFWA+ + +L Sbjct: 324 LRAERRLHSAVPLGVAALAFVGAGFIGHPAVAMAMLSLSLAGLYAFKSPFWALPTLFLTR 383 Query: 367 GSAAAGLAGINAVSNLIG 384 +AA +A IN+V NL G Sbjct: 384 STAAVSIAVINSVGNLGG 401 >STM1107 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 458 Score = 319 bits (817), Expect = 9e-87, Method: Compositional matrix adjust. Identities = 176/440 (40%), Positives = 254/440 (57%), Gaps = 15/440 (3%) Query: 2 ETIQNEKRL---EQETVRKVTWRLLPFLMLCYLFAFIDRGNIGMAALQMNHDLGLSPKMF 58 E++ + L +Q + K+ RL+ FL + ++F+F+DR NIG A L M DLGLS MF Sbjct: 13 ESVSSHNALSTGQQTVINKLFRRLIVFLFVLFIFSFLDRINIGFAGLTMGQDLGLSATMF 72 Query: 59 GFASSLFFIAYFIFEVPSNLALQKFGARKWLARIMITWGLVSACTALVQGPNSLYFVRFI 118 G A++LF+ Y IF +PSN+ L GAR W+A IM+ WG+ S T GP SLY +R + Sbjct: 73 GLATTLFYATYVIFGIPSNVMLSIVGARHWIATIMVLWGIASTATMFAVGPKSLYVLRML 132 Query: 119 LGAAEAGFFPGVVLYLTYWVPSTYRARIVALFMVAIPAASFVASPVSALLLQMDGIGGLR 178 +G EAGF PG++LYLTYW P+ +RAR ALFM+A+PA + + S VS +L +DGI L Sbjct: 133 VGITEAGFLPGILLYLTYWFPAFFRARANALFMIAMPATTALGSIVSGYILSLDGIFNLH 192 Query: 179 GWHWLFMLEGLPTVVLGLVCLSFLTDRPDQARWLSDEQRQWLTETMNKE---------AA 229 GW WLF+LEG P+V+LG++ +L D P +A+WL+ E ++ L E M+ + A Sbjct: 193 GWQWLFLLEGFPSVLLGIMVWFYLDDTPAKAKWLTAEDKKCLQEMMDSDRLTLVQPEGAI 252 Query: 230 SRAAKQHIPLWKLFSQPHVWGMALVCACASAAGSVLNVWQPQLLKSF--GLSVMQTGLVN 287 S A Q LW+ P V L C + S +++W PQ+LKSF G S + GL+ Sbjct: 253 SHNAMQQRSLWREVFTPIVLMYTLAYFCLTNTLSAISIWTPQILKSFNEGSSNITIGLLA 312 Query: 288 SIPYLIASVLMVWWGRHSDRTGERRWHTAIPLMLIGGGLALASLAHSLAPVVLLLTMVLI 347 +IP + + M++W RHSD+ ER+ HTA+P + G LAS +L + M Sbjct: 313 AIPQICTILGMIYWSRHSDKHQERKHHTALPFLFAAAGWLLASATDHNLIQLLGIVMAST 372 Query: 348 GAYSFKGPFWAMASSWLATGSAAAGLAGINAVSNLIGGGLMVNVYGWVKDATGSYAMALL 407 G++S FW ++ + A G+A INA N IG L + GW+KD TGS+ L Sbjct: 373 GSFSAMAIFWTTPDQSISLRARAIGIAVINATGN-IGSALSPFMIGWLKDITGSFNSGLW 431 Query: 408 PMVGLSVVSVGILLFLSRKS 427 + L VV I+ + K+ Sbjct: 432 FVASLLVVGAAIIWLIPMKA 451 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 306 bits (785), Expect = 5e-83, Method: Compositional matrix adjust. Identities = 181/427 (42%), Positives = 265/427 (62%), Gaps = 9/427 (2%) Query: 5 QNEKRLEQETVRKVTWRLLPFLMLCYLFAFIDRGNIGMAALQMNHDLGLSPKMFGFASSL 64 Q+ E+ T RKV+WRL+PFL+LCY+ A++DR N+G A LQM +DL S ++G + + Sbjct: 18 QSASGFEEATYRKVSWRLIPFLLLCYVVAYLDRVNVGFAKLQMLNDLKFSETVYGLGAGI 77 Query: 65 FFIAYFIFEVPSNLALQKFGARKWLARIMITWGLVSACTALVQGPNSLYFVRFILGAAEA 124 FFI YF+FEVPSN+ L + GAR W+ARIMI+WGL+SA V P Y +RF+LG AEA Sbjct: 78 FFIGYFLFEVPSNVILHRVGARMWIARIMISWGLISAAMMFVTTPAMFYVMRFLLGLAEA 137 Query: 125 GFFPGVVLYLTYWVPSTYRARIVALFMVAIPAASFVASPVSALLLQ-MDGIGGLRGWHWL 183 GFFPG++LYLTYW P+ R R FM A+ + + P+S L+ G+ GL GW W+ Sbjct: 138 GFFPGIILYLTYWYPAERRGRTTTFFMTAVALSGVIGGPISGWALKTFGGVYGLAGWQWM 197 Query: 184 FMLEGLPTVVLGLVCLSFLTDRPDQARWLSDEQRQWLTETMNKEAASRAAKQHIPLWKLF 243 F++EG+P+VV+GL L++L +R ARWL+DE++ LT + AA A K+ P+ + Sbjct: 198 FLIEGIPSVVIGLCVLAYLDNRISHARWLTDEEKALLTRNI---AAEEAQKEDAPIAAIM 254 Query: 244 SQPHVWGMALVCACASAAGSVLNVWQPQLLKSFGLS-VMQTGLVNSIPYLIASVLMVWWG 302 + P VW M+L+ ++ W P L+K G++ + GL+ +IPY A V MV Sbjct: 255 ASPRVWLMSLIYFSFVMGLYGVSFWLPTLIKQTGVADPLSVGLLTAIPYGAAVVAMVLVA 314 Query: 303 RHSDRTGERRWHTAIPLMLIGGGLALASLAHSLAPVVL-LLTMVLIGAYSFKGPFWAMAS 361 R +DRT ERRWH AIP + GL L+++ H+ + + LT+ +G + FW++ + Sbjct: 315 RSADRTRERRWHIAIPALAGAIGLVLSAVWHTNTTLAMAALTLGTMGILTTLPLFWSLPT 374 Query: 362 SWLATGSAAAGLAGINAVSNLIGGGLMVNVYGWVKDATGSYAMALLPMVGLSVVSVGILL 421 ++LA AAAG+A IN++ NL G L GW+KD T S + ++ S+V +G LL Sbjct: 375 AFLAGTGAAAGIALINSLGNL-AGFLSPYAVGWLKDTTRSTDSGMY-LLAASMV-LGALL 431 Query: 422 FLSRKSR 428 LS +R Sbjct: 432 TLSVPAR 438 >BMEII1096 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 451 Score = 302 bits (773), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 166/420 (39%), Positives = 256/420 (60%), Gaps = 5/420 (1%) Query: 4 IQNEKRLEQETVRKVTWRLLPFLMLCYLFAFIDRGNIGMAALQMNHDLGLSPKMFGFASS 63 I + + +E T RKV +R++P LM+CY+ A++DR N+G A LQM+ +LG S ++G + Sbjct: 26 ITSPEVVENMTYRKVAFRIIPLLMICYIIAYLDRVNVGFAKLQMSEELGFSEAIYGLGAG 85 Query: 64 LFFIAYFIFEVPSNLALQKFGARKWLARIMITWGLVSACTALVQGPNSLYFVRFILGAAE 123 LFFI YF FE+PSN+ L K GAR W+ARIMITWGL+SA A VQ Y +RF+LGAAE Sbjct: 86 LFFIGYFFFEIPSNILLHKLGARLWIARIMITWGLLSALFAFVQTEWQFYILRFLLGAAE 145 Query: 124 AGFFPGVVLYLTYWVPSTYRARIVALFMVAIPAASFVASPVSA-LLLQMDGIGGLRGWHW 182 AGF+PGV+LYLTYW PS R + ALF PAA +P+S ++ Q G +GW W Sbjct: 146 AGFYPGVILYLTYWFPSHRRGNMFALFQAGSPAAGIFGNPLSGWIMDQFHDTAGWQGWQW 205 Query: 183 LFMLEGLPTVVLGLVCLSFLTDRPDQARWLSDEQRQWLTETMNKEAASRAAKQHIPLWKL 242 +F+LE +P VVLG+V L +L + A+WL++E++ ++ + ++ +AA L L Sbjct: 206 MFVLEAIPAVVLGVVILLYLDNSVKAAKWLTEEEKAIISRDIEADSKGKAASHS--LMSL 263 Query: 243 FSQPHVWGMALVCACASAAGSVLNVWQPQLLKSFGL-SVMQTGLVNSIPYLIASVLMVWW 301 P +W M L+ C L +W P L+++ G+ S + GL+ +IP++ A + MV + Sbjct: 264 VKNPMLWVMMLIYFCFVMGQHGLTLWMPTLIRASGVTSNVTIGLLGAIPFICAIIAMVIF 323 Query: 302 GRHSDRTGERRWHTAIPLMLIGGGLALASLAHSLAPVVLLLTMVLIGAYSFKGPFWAMAS 361 R +D ERRWH +P +L G +A+ A + ++ L+M G + FW++ + Sbjct: 324 SRSADHYRERRWHLVVPALLGAVGFVVAASATNTTVSIIFLSMAAAGVLACAPLFWSLPT 383 Query: 362 SWLATGSAAAGLAGINAVSNLIGGGLMVNVYGWVKDATGSYAMALLPMVGLSVVSVGILL 421 + L+ +AAAG+A IN+V+NL G + + G ++DAT S + + + G ++ I+L Sbjct: 384 AILSGAAAAAGIALINSVANL-AGFISPYMVGIIRDATHSSELGMYVLAGFLILGAAIVL 442 >YPO2237 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 436 Score = 300 bits (767), Expect = 5e-81, Method: Compositional matrix adjust. Identities = 163/411 (39%), Positives = 252/411 (61%), Gaps = 9/411 (2%) Query: 2 ETIQNEKRLEQET--VRKVTWRLLPFLMLCYLFAFIDRGNIGMAALQMNHDLGLSPKMFG 59 E++ +L++E RK W LLP LMLCY+ ++DR N+G A LQM DL S ++G Sbjct: 7 ESLSQPTQLQEENNAYRKTVWHLLPLLMLCYVLNYLDRVNVGFAKLQMADDLQFSDTVYG 66 Query: 60 FASSLFFIAYFIFEVPSNLALQKFGARKWLARIMITWGLVSACTALVQGPNSLYFVRFIL 119 + +FFI YF E+PSNL L + GAR W+ARIMITWG++SAC A V P S Y +RF+L Sbjct: 67 LGAGMFFIGYFFLEIPSNLILHRVGARLWIARIMITWGIISACMAFVTTPMSFYVMRFLL 126 Query: 120 GAAEAGFFPGVVLYLTYWVPSTYRARIVALFMVAIPAASFVASPVSALLLQ-MDGIGGLR 178 G AEAGFFPG++LY++YW PS R R+ LF++++P + + +P+S ++Q +G G Sbjct: 127 GVAEAGFFPGIILYISYWFPSHRRGRVYGLFVISVPLSGIIGAPLSGWIMQYFNGFQGYA 186 Query: 179 GWHWLFMLEGLPTVVLGLVCLSFLTDRPDQARWLSDEQRQWLTETMNKEAASRAAKQHIP 238 GW W+F+LEG+P+V++G++ + L DR A WL+D+++ L + EAA A H Sbjct: 187 GWQWMFILEGIPSVLVGILIIYKLKDRITHATWLTDKEKDILQTNIENEAAHYA---HSR 243 Query: 239 LWKLFSQPHVWGMALVCACASAAGSVLNVWQPQLLKSFGL-SVMQTGLVNSIPYLIASVL 297 L F QP VW + L+ C + + W P L++ G+ ++ G + +IP A+V Sbjct: 244 LRDAFLQPRVWLLTLIYFCLISGFYTIGFWLPTLIRDSGVKDILSIGFLTAIPSAAAAVT 303 Query: 298 MVWWGRHSDRTGERRWHTAIPLMLIGGGLALAS-LAHSLAPVVLLLTMVLIGAYSFKGPF 356 M+ R +DR ERRWH A+ +L G+ L++ + ++ ++ LT+ +GA S F Sbjct: 304 MIVVSRSADRLRERRWHLALTAVLGAVGIILSTYFSDNIVVAMVCLTIGAMGALSTIPLF 363 Query: 357 WAMASSWLATGSAAAGLAGINAVSNLIGGGLMVNVYGWVKDATGSYAMALL 407 W++ +++L +AAAG+A IN+ NL GG + + G++KD T S +L Sbjct: 364 WSLPTAFLGGSAAAAGIAFINSWGNL-GGFVAPYMMGYLKDLTQSTTTGML 413