BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0041.0210.p (402 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1031 [H] COG1488 Nicotinic acid phosphoribosyltransferase Rso... 608 e-174 XF1097 [H] COG1488 Nicotinic acid phosphoribosyltransferase Xfa ... 546 e-155 NMA1706 [H] COG1488 Nicotinic acid phosphoribosyltransferase NmA... 417 e-116 NMB1505 [H] COG1488 Nicotinic acid phosphoribosyltransferase Nme... 414 e-115 PA4919 [H] COG1488 Nicotinic acid phosphoribosyltransferase Pae ... 395 e-109 >RSc1031 [H] COG1488 Nicotinic acid phosphoribosyltransferase Rso Ralstonia solanacearum Length = 404 Score = 608 bits (1568), Expect = e-174, Method: Compositional matrix adjust. Identities = 285/398 (71%), Positives = 327/398 (82%), Gaps = 2/398 (0%) Query: 5 GQPHPDF-MIITSLLDTDLYKFTMMQVVLHHFPGAQVEYRFKCRNENVDLRPYVDEIRAE 63 G P P MII SLLDTDLYKFTMMQVVLHHFPGA VEYRFKCRN VDL PY++ IRAE Sbjct: 8 GAPLPAVPMIIRSLLDTDLYKFTMMQVVLHHFPGAHVEYRFKCRNPGVDLVPYIEAIRAE 67 Query: 64 IAALCRLRFKEDELNYLRSLRFIKSDFVDFLDLFHLNEKYITVQPDPAGNGEIEISVKGP 123 I LC LRF E EL+YLR LRFIKSDFVDFLDLFHL+EKYI ++P + +G+I+I + GP Sbjct: 68 IRHLCSLRFTEAELDYLRGLRFIKSDFVDFLDLFHLSEKYIDIRPAASNDGQIDIVISGP 127 Query: 124 WLHTIMFEVPVLAIVNEVYFRATQRSPDLEEGRARLRKKMSVITDDPELAGCKIADYGTR 183 WLHTIMFEVPVLAIVNEVYF TQ P +EG+ RL +K++ +T P L C+IADYGTR Sbjct: 128 WLHTIMFEVPVLAIVNEVYFSRTQAHPQWDEGKRRLTEKLASLTR-PGLEDCRIADYGTR 186 Query: 184 RRFSRSWHAEVIDEMKQHMGDHFAGTSNVMYAMQHDLTPLGTMAHEYLQACQALGPRLRD 243 RRFS +WH V+ E + +G +AGTSNV +AM+H++TPLGTMAHEYLQACQ+LGPRLRD Sbjct: 187 RRFSHTWHEHVLMEARSQLGSQYAGTSNVYFAMKHNMTPLGTMAHEYLQACQSLGPRLRD 246 Query: 244 SQTFAFEMWAREYRGDLGITLSDVYGMDAFLRDYDMYFCKLFDGARHDSGDPFEWGERLI 303 SQ FA E WAREYRGDLGI LSD YG DAFLRD+DM+FCKLFDG RHDSGDPFEWGER++ Sbjct: 247 SQVFALETWAREYRGDLGIALSDTYGFDAFLRDFDMFFCKLFDGVRHDSGDPFEWGERML 306 Query: 304 QHYRDNRVDPSSKVLVFSDSLDFDKVRALYLRFKDRAKVAFGVGTNLTNDLGYTPLQVVM 363 +HY RVDP SK L+FSDSLD KV LY RF+ R K+AFGVGTNLTNDLGYTPLQ+V+ Sbjct: 307 KHYEGMRVDPQSKALIFSDSLDMPKVVRLYERFRSRCKLAFGVGTNLTNDLGYTPLQIVI 366 Query: 364 KMVRCNGQPVAKLSDTPSKNMCDDPAYVNYLRQVFQIK 401 KMVRCNGQPVAKLSD P K MCDDPAY+ YL+QVF ++ Sbjct: 367 KMVRCNGQPVAKLSDAPEKTMCDDPAYLAYLKQVFGVQ 404 >XF1097 [H] COG1488 Nicotinic acid phosphoribosyltransferase Xfa Xylella fastidiosa 9a5c Length = 394 Score = 546 bits (1406), Expect = e-155, Method: Compositional matrix adjust. Identities = 256/390 (65%), Positives = 310/390 (79%), Gaps = 1/390 (0%) Query: 13 IITSLLDTDLYKFTMMQVVLHHFPGAQVEYRFKCRNENVDLRPYVDEIRAEIAALCRLRF 72 II SLLDTDLYKFTMMQ VLH +PGAQVEYRFKCR VDL +++EI EI LC LRF Sbjct: 4 IIKSLLDTDLYKFTMMQAVLHQYPGAQVEYRFKCRTPGVDLARFINEISHEIDGLCALRF 63 Query: 73 KEDELNYLRSLRFIKSDFVDFLDLFHLNEKYITVQPDPAGNGEIEISVKGPWLHTIMFEV 132 ++EL+YLR LRF+K DFVDFL LFHL+ KY+ ++ +GEIE+ ++GPWLHTI+FEV Sbjct: 64 SKEELDYLRGLRFMKPDFVDFLGLFHLDRKYLQLRASTQVSGEIELDIRGPWLHTILFEV 123 Query: 133 PVLAIVNEVYFRATQRSPDLEEGRARLRKKMSVITDDPELAGCKIADYGTRRRFSRSWHA 192 P+LAI+NEV+FR T +L+ GRARL K+ ++ + C IADYGTRRR+SR WHA Sbjct: 124 PLLAIINEVWFRNTSML-NLDVGRARLDAKVRLLKGESGYEECSIADYGTRRRYSRQWHA 182 Query: 193 EVIDEMKQHMGDHFAGTSNVMYAMQHDLTPLGTMAHEYLQACQALGPRLRDSQTFAFEMW 252 E++ + Q +G +F GTSNV +A Q+ TPLGTMAHEYLQA QALGPRLRDSQ E W Sbjct: 183 ELLPLLAQGLGSNFVGTSNVYFAKQYGYTPLGTMAHEYLQAFQALGPRLRDSQVAGLEAW 242 Query: 253 AREYRGDLGITLSDVYGMDAFLRDYDMYFCKLFDGARHDSGDPFEWGERLIQHYRDNRVD 312 AREYRGDLGI LSDV G+DAFL D+D+YFCKLFDG RHDSGDPF+WGER+I H +R+D Sbjct: 243 AREYRGDLGIALSDVVGLDAFLGDFDLYFCKLFDGMRHDSGDPFKWGERIIMHLESHRID 302 Query: 313 PSSKVLVFSDSLDFDKVRALYLRFKDRAKVAFGVGTNLTNDLGYTPLQVVMKMVRCNGQP 372 P +KVLVFSD LD +KV LY F+ R ++AFGVGT+LTNDLG TPLQ+V+KMVRCNGQP Sbjct: 303 PRTKVLVFSDGLDMNKVMRLYQHFRGRCRLAFGVGTSLTNDLGPTPLQIVIKMVRCNGQP 362 Query: 373 VAKLSDTPSKNMCDDPAYVNYLRQVFQIKA 402 VAKLSD+P K+MCDDPAY++YLRQVF + A Sbjct: 363 VAKLSDSPGKSMCDDPAYLHYLRQVFGVSA 392 >NMA1706 [H] COG1488 Nicotinic acid phosphoribosyltransferase NmA Neisseria meningitidis Z2491 Length = 419 Score = 417 bits (1071), Expect = e-116, Method: Compositional matrix adjust. Identities = 204/396 (51%), Positives = 272/396 (68%), Gaps = 11/396 (2%) Query: 13 IITSLLDTDLYKFTMMQVVLHHFPGAQVEYRFKCRNENVDLRPYVD---EIRAEIAALCR 69 II SLLDTDLYKFTM+QVVLH FP Y F+CRN + + P D ++ E+ ALC+ Sbjct: 21 IIHSLLDTDLYKFTMLQVVLHQFPQTHSLYEFRCRNAST-VYPLADIKEDLEVELDALCQ 79 Query: 70 LRFKEDELNYLRSLRFIKSDFVDFLDLFHLNEKYITVQPDPAGNGEIEISVKGPWLHTIM 129 LRF DEL+YLRSLRFIKSDFVD+L+LF L +++ V D G + I ++GP + + Sbjct: 80 LRFTHDELDYLRSLRFIKSDFVDYLELFQLQRRFVEVGTD--DKGRLNIRIEGPMIQAMF 137 Query: 130 FEVPVLAIVNEVYFRATQRSPDLEEGRARLRKKMSVITD-----DPELAGCKIADYGTRR 184 FE+ +LAIVNE+YFR + +EEG RL+ K + + + +P+ I+D+GTRR Sbjct: 138 FEIFILAIVNELYFRRLETPAVIEEGERRLQAKAARLKEIAAAQNPDEPPFLISDFGTRR 197 Query: 185 RFSRSWHAEVIDEMKQHMGDHFAGTSNVMYAMQHDLTPLGTMAHEYLQACQALGPRLRDS 244 R+ +W VI + + GTSNV A + +TP+GTMAHE+LQA QAL RLR+ Sbjct: 198 RYKLAWQEHVIRTLLEAAPSIVRGTSNVFLAKKLGITPIGTMAHEFLQAFQALDVRLRNF 257 Query: 245 QTFAFEMWAREYRGDLGITLSDVYGMDAFLRDYDMYFCKLFDGARHDSGDPFEWGERLIQ 304 Q A E W EYRGDLG+ L+DV GMDAFLRD+D+YF KLFDG RHDSGDP+ WG++ Sbjct: 258 QKAALESWVHEYRGDLGVALTDVVGMDAFLRDFDLYFAKLFDGLRHDSGDPYIWGDKAYA 317 Query: 305 HYRDNRVDPSSKVLVFSDSLDFDKVRALYLRFKDRAKVAFGVGTNLTNDLGYTPLQVVMK 364 HY+ ++D +K+L FSD LD ++ AL+ FKDR K FG+GTNLTND+G+TPL +V+K Sbjct: 318 HYQKLKIDSRTKMLTFSDGLDIERSWALHQYFKDRFKTGFGIGTNLTNDMGHTPLNIVLK 377 Query: 365 MVRCNGQPVAKLSDTPSKNMCDDPAYVNYLRQVFQI 400 +V CNGQ VAKLSD+P K M ++ ++ YLRQVF + Sbjct: 378 LVECNGQSVAKLSDSPGKTMTNNSTFLAYLRQVFDV 413 >NMB1505 [H] COG1488 Nicotinic acid phosphoribosyltransferase Nme Neisseria meningitidis MC58 Length = 402 Score = 414 bits (1065), Expect = e-115, Method: Compositional matrix adjust. Identities = 203/396 (51%), Positives = 271/396 (68%), Gaps = 11/396 (2%) Query: 13 IITSLLDTDLYKFTMMQVVLHHFPGAQVEYRFKCRNENVDLRPYVD---EIRAEIAALCR 69 II SLLDTDLYKFTM+QVVLH FP Y F+CRN + + P D ++ AE+ ALC+ Sbjct: 4 IIHSLLDTDLYKFTMLQVVLHQFPQTHSLYEFRCRNAST-VYPLADIREDLEAELDALCQ 62 Query: 70 LRFKEDELNYLRSLRFIKSDFVDFLDLFHLNEKYITVQPDPAGNGEIEISVKGPWLHTIM 129 LRF DEL YLRSLRFIKSDFVD+L+LF L +++ + D + I ++GP + + Sbjct: 63 LRFTHDELGYLRSLRFIKSDFVDYLELFQLQRRFVEIGTD--DKDRLNIRIEGPMIQAMF 120 Query: 130 FEVPVLAIVNEVYFRATQRSPDLEEGRARLRKKMSVITD-----DPELAGCKIADYGTRR 184 FE+ +LAIVNE+YFR + +EEG RL+ K + + + +P+ I+D+GTRR Sbjct: 121 FEIFILAIVNELYFRRLETPAVIEEGERRLQAKAARLKEIAAAQNPDEPPFLISDFGTRR 180 Query: 185 RFSRSWHAEVIDEMKQHMGDHFAGTSNVMYAMQHDLTPLGTMAHEYLQACQALGPRLRDS 244 R+ +W VI + + GTSNV A + +TP+GTMAHE+LQA QAL RLR+ Sbjct: 181 RYKLAWQEHVIRTLLEAAPGIVRGTSNVFLAKKLGITPIGTMAHEFLQAFQALDVRLRNF 240 Query: 245 QTFAFEMWAREYRGDLGITLSDVYGMDAFLRDYDMYFCKLFDGARHDSGDPFEWGERLIQ 304 Q A E W EYRGDLG+ L+DV GMDAFLRD+D+YF KLFDG RHDSGDP+ WG++ Sbjct: 241 QKAALESWVHEYRGDLGVALTDVVGMDAFLRDFDLYFAKLFDGLRHDSGDPYVWGDKAYA 300 Query: 305 HYRDNRVDPSSKVLVFSDSLDFDKVRALYLRFKDRAKVAFGVGTNLTNDLGYTPLQVVMK 364 HY+ ++D +K+L FSD LD ++ AL+ FKDR K FG+GTNLTND+G+TPL +V+K Sbjct: 301 HYQKLKIDSRTKMLTFSDGLDIERSWALHQYFKDRFKTGFGIGTNLTNDMGHTPLNIVLK 360 Query: 365 MVRCNGQPVAKLSDTPSKNMCDDPAYVNYLRQVFQI 400 +V CNGQ VAKLSD+P K M ++ ++ YLRQVF + Sbjct: 361 LVECNGQSVAKLSDSPGKTMTNNSTFLAYLRQVFDV 396 >PA4919 [H] COG1488 Nicotinic acid phosphoribosyltransferase Pae Pseudomonas aeruginosa Length = 399 Score = 395 bits (1014), Expect = e-109, Method: Compositional matrix adjust. Identities = 199/394 (50%), Positives = 257/394 (65%), Gaps = 8/394 (2%) Query: 13 IITSLLDTDLYKFTMMQVVLHHFPGAQVEYRFKCRNENVDLRPYVDEIRAEIAALCRLRF 72 I+ +LLDTD YK TMMQ VLH++P A+VE+ F+CRN DLRPY+ EIR +I L + Sbjct: 10 IVQNLLDTDFYKLTMMQAVLHNYPNAEVEWEFRCRNAE-DLRPYLAEIRYQIERLAEVEV 68 Query: 73 KEDELNYLRSLRFIKSDFVDFLDLFHLNEKYITVQPDPAGNGEIEISVKGPWLHTIMFEV 132 D+L +L + F+K DF+ FL LF N +Y+ + +G++ I ++GPWLH I+FEV Sbjct: 69 TADQLAFLERIPFMKPDFIRFLSLFRFNLRYVHTGIE---DGQLAIRLRGPWLHVILFEV 125 Query: 133 PVLAIVNEVYFRATQRSPDLEEGRARLRKKM---SVITDDPELAGCKIADYGTRRRFSRS 189 P+LAIV+EV R R LE+ +L +K+ S ELA ++AD+GTRRRFS Sbjct: 126 PLLAIVSEVRNRYRYREVVLEQVGEQLYRKLDWLSAQASSEELAEFQVADFGTRRRFSYR 185 Query: 190 WHAEVIDEMKQHMGDHFAGTSNVMYAMQHDLTPLGTMAHEYLQACQALGPRLRDSQTFAF 249 EV+ +K+ F GTSNV A ++DL P+GTMAHE+L A Q LGPRL DSQ A Sbjct: 186 TQEEVVHILKRDFPGRFVGTSNVHLAREYDLKPIGTMAHEWLMAHQQLGPRLVDSQQAAL 245 Query: 250 EMWAREYRGDLGITLSDVYGMDAFLRDYDMYFCKLFDGARHDSGDPFEWGERLIQHYRDN 309 + W REYRG LGI L+D MDAFL D+D+YF KLFDG RHDSGDP W E+ I HYR Sbjct: 246 DCWVREYRGQLGIALTDCITMDAFLDDFDLYFAKLFDGLRHDSGDPLAWAEKAIAHYRRL 305 Query: 310 RVDPSSKVLVFSDSLDFDKVRALYLRFKDRAKVAFGVGTNLTNDL-GYTPLQVVMKMVRC 368 +DP SK LVFSD LD K L+ + + V+FG+GTNLT D+ G P+ +V+KM C Sbjct: 306 GIDPLSKTLVFSDGLDMPKALQLFRALRGKINVSFGIGTNLTCDIPGVEPMNIVLKMTAC 365 Query: 369 NGQPVAKLSDTPSKNMCDDPAYVNYLRQVFQIKA 402 NG PVAK+SD P K C D +V YLR VF + A Sbjct: 366 NGHPVAKISDAPGKTQCRDENFVAYLRHVFNVPA 399