BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0041.0144.p (480 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4132 [KE] COG1167 Transcriptional regulators containing a DNA-... 463 e-130 YPO1960 [KE] COG1167 Transcriptional regulators containing a DNA... 405 e-113 STM1598 [KE] COG1167 Transcriptional regulators containing a DNA... 391 e-108 ydcR [KE] COG1167 Transcriptional regulators containing a DNA-bi... 384 e-106 ECs2043 [KE] COG1167 Transcriptional regulators containing a DNA... 384 e-106 >PA4132 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Pae Pseudomonas aeruginosa Length = 471 Score = 463 bits (1192), Expect = e-130, Method: Compositional matrix adjust. Identities = 229/475 (48%), Positives = 319/475 (67%), Gaps = 8/475 (1%) Query: 7 YKQFADQLAASIRDGVLRPGERIASVRIASQQHKVSVTTVVRAYELLESLGIIESQPQSG 66 Y++FAD++A IR GVL PG+++ SVR AS+ + VS +TV +AY LLES G+I ++ +SG Sbjct: 4 YEKFADEIAELIRTGVLAPGQKVPSVRHASRTYGVSASTVFQAYYLLESRGLIMARARSG 63 Query: 67 YFVREQPEAP-PKPALRTTSREDHPAWQESTEVDVSRLVLATLKTIQQDGTVPLGSPYPN 125 YFV + + P P+P E P ++TEVDVS LV + L +I+ TVP GS +P+ Sbjct: 64 YFVCQHVQRPLPEP-------EISPRQADATEVDVSELVFSVLSSIKDPDTVPFGSAFPS 116 Query: 126 PALFPSHRLAQYAGRIARHASQSSVFDDLPPGHPELLRQIARRYLENGLKVDPEEIVITV 185 P LFP RLA+ R SV D+ PG+ L RQIA RY+ GL + EE+VI+ Sbjct: 117 PQLFPLPRLARSMAHAVRDMDPQSVVADMTPGNHGLRRQIALRYMVGGLLLPVEELVISN 176 Query: 186 GATEAINLCLQAVARPGDTIAVETPTFYAMLHAIERLGMRALEIPTDPQRGIDVGALEER 245 GA EA+NLCLQ V RPGD +A+E P FYA L +ERL ++A+EIP P+ GID+ L + Sbjct: 177 GALEALNLCLQVVTRPGDLVAIEAPAFYATLQVLERLKLKAVEIPVHPREGIDLEVLADS 236 Query: 246 MKTQAIAACMVMPNFQNPLGFQMPDSEKERLVRLAEQHQMPVIENAVYSELYYGNAHPSS 305 ++ I AC M NFQNP+G M D +K L L +HQ+P+IE+ VY+ELY+G P Sbjct: 237 LERLPIKACWFMSNFQNPMGASMDDEKKRALAELLARHQVPMIEDDVYAELYFGQQAPKP 296 Query: 306 LKNYDRDGLVLHCSSFSKSLTSAYRIGWAMPGRYRAQVEKLKFLNTLATPTAPQRAIAEY 365 +K YD++GLV+HCSSFSKSL YR+GW GRY Q+E+LK + +L+ Q AIA+Y Sbjct: 297 VKAYDQEGLVMHCSSFSKSLAPGYRVGWVAGGRYAEQIERLKLMTSLSASIPAQAAIADY 356 Query: 366 LTQGGYERHLRRVRRAFAQQRDMMRHFVLRFFPAGTQVSEPQGGYVLWVELPQGVDAMEL 425 L GGY+RHLR++R A Q++ M V R+FP T+VS P GGY LW+ELP+ VD++ L Sbjct: 357 LQHGGYDRHLRKLRYALETQQNAMLAAVARYFPEQTRVSRPSGGYFLWLELPEAVDSLRL 416 Query: 426 YRRSLALGITVAPGRIFAATNRYSHFIRLNYSYAWSKETEQALKLVGKLVEELAG 480 ++ +LA GI++APG IF+AT R++H RLNY + WS E+A++ +G++ + LAG Sbjct: 417 FQLALAQGISLAPGPIFSATRRFAHCARLNYGHPWSARQEKAMETLGRITQSLAG 471 >YPO1960 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Ype Yersinia pestis Length = 473 Score = 405 bits (1042), Expect = e-113, Method: Compositional matrix adjust. Identities = 196/472 (41%), Positives = 301/472 (63%), Gaps = 7/472 (1%) Query: 7 YKQFADQLAASIRDGVLRPGERIASVRIASQQHKVSVTTVVRAYELLESLGIIESQPQSG 66 Y+Q A Q+ A I+ V + G+++ S+R + +Q +S+ TVV++Y+LLES G I ++PQSG Sbjct: 4 YEQLAQQIRAQIQSKVWQAGDKLPSLRESCKQSGLSLMTVVQSYQLLESQGWIVARPQSG 63 Query: 67 YFVREQPEAPPKPALRTTSREDHPAWQESTEVDVSRLVLATLKTIQQDGTVPLGSPYPNP 126 Y+V +P P+P D +VD++ + L+ + +P GS +P+P Sbjct: 64 YYVASRPTQLPQPQRGNKLHLDE-------QVDINTFIFNVLQAGKDPAIMPFGSAFPDP 116 Query: 127 ALFPSHRLAQYAGRIARHASQSSVFDDLPPGHPELLRQIARRYLENGLKVDPEEIVITVG 186 +L RL++ +AR S S +LPPG+ L R IA+RY G+ V PEEIVIT G Sbjct: 117 SLLLQPRLSRALASVARKISPQSSVTNLPPGNESLRRNIAQRYAACGMNVSPEEIVITAG 176 Query: 187 ATEAINLCLQAVARPGDTIAVETPTFYAMLHAIERLGMRALEIPTDPQRGIDVGALEERM 246 A E+++L LQAV +PGD + +E+P FY L AIERL ++A+ I TDPQ+G+D+ ALE+ + Sbjct: 177 AMESLSLSLQAVTQPGDWVVIESPAFYGALQAIERLRLKAIAITTDPQQGVDLEALEQVI 236 Query: 247 KTQAIAACMVMPNFQNPLGFQMPDSEKERLVRLAEQHQMPVIENAVYSELYYGNAHPSSL 306 I AC +MP+FQNP+G MP S+K+RLV L +Q + +IE+ VY ELY+G Sbjct: 237 SQYPIKACWLMPHFQNPMGATMPWSQKQRLVTLLQQKAISLIEDDVYGELYFGAERLLPA 296 Query: 307 KNYDRDGLVLHCSSFSKSLTSAYRIGWAMPGRYRAQVEKLKFLNTLATPTAPQRAIAEYL 366 K D+ +LHCSSFSK L +R+GW G + +++ L+ ++T++ Q AIA+YL Sbjct: 297 KALDQHRQILHCSSFSKCLAPGFRVGWVAAGEHAQRIQHLQLMSTVSASVPTQLAIADYL 356 Query: 367 TQGGYERHLRRVRRAFAQQRDMMRHFVLRFFPAGTQVSEPQGGYVLWVELPQGVDAMELY 426 +QGGY+ HLRR+RR Q+ + V+ FP ++S P GGY LW+EL +A ELY Sbjct: 357 SQGGYDTHLRRLRRVMEQRMSTLHQAVVEHFPKNIKISHPAGGYFLWLELEPPFNASELY 416 Query: 427 RRSLALGITVAPGRIFAATNRYSHFIRLNYSYAWSKETEQALKLVGKLVEEL 478 RR+L G+++APGR+F +++ H RLN S+AWS+++ +A++++ KL+ +L Sbjct: 417 RRALEQGVSIAPGRMFTTGSQFDHCFRLNASFAWSEQSAKAIRILAKLIGQL 468 >STM1598 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Sty Salmonella typhimurium LT2 Length = 474 Score = 391 bits (1005), Expect = e-108, Method: Compositional matrix adjust. Identities = 196/472 (41%), Positives = 292/472 (61%), Gaps = 8/472 (1%) Query: 7 YKQFADQLAASIRDGVLRPGERIASVRIASQQHKVSVTTVVRAYELLESLGIIESQPQSG 66 Y++ A+Q+ I GV +PG+R+ S+R +S TV AY+LLES G I ++PQSG Sbjct: 4 YQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSG 63 Query: 67 YFVREQPEAPPKPALRTTSREDHPAWQESTEVDVSRLVLATLKTIQQDGTVPLGSPYPNP 126 Y+V P P R+ + H E+ VD++ + L+ + VP S +P+P Sbjct: 64 YYV------APHPVCRSVATAAHVIRDEA--VDINTYIFEMLQASRDTSVVPFASAFPDP 115 Query: 127 ALFPSHRLAQYAGRIARHASQSSVFDDLPPGHPELLRQIARRYLENGLKVDPEEIVITVG 186 LFP +L + ++++ A+ SV ++LPPG+ EL IARRY + G+ V P+EIVIT G Sbjct: 116 RLFPLPQLNRSLAQVSKTATAMSVIENLPPGNAELRYAIARRYAQQGITVSPDEIVITAG 175 Query: 187 ATEAINLCLQAVARPGDTIAVETPTFYAMLHAIERLGMRALEIPTDPQRGIDVGALEERM 246 A EA+NL LQAV PGD + VE P FY L A+ERL ++AL IPTD + GID+ ALE+ + Sbjct: 176 ALEALNLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALSIPTDVKEGIDLMALEQAL 235 Query: 247 KTQAIAACMVMPNFQNPLGFQMPDSEKERLVRLAEQHQMPVIENAVYSELYYGNAHPSSL 306 + + AC +M N QNPLGF + +K RLV L H + +IE+ VYSELY+G P Sbjct: 236 QEYPVKACWLMTNSQNPLGFTLSAEKKARLVALLTHHNVTLIEDDVYSELYFGREKPLPA 295 Query: 307 KNYDRDGLVLHCSSFSKSLTSAYRIGWAMPGRYRAQVEKLKFLNTLATPTAPQRAIAEYL 366 K +DRD VLHCSSFSK L +RIGW G + Q+++L+ ++TL+T + Q A+ +YL Sbjct: 296 KAWDRDDTVLHCSSFSKCLVPGFRIGWVAGGSHARQIQRLQLMSTLSTSSPMQLALVDYL 355 Query: 367 TQGGYERHLRRVRRAFAQQRDMMRHFVLRFFPAGTQVSEPQGGYVLWVELPQGVDAMELY 426 + Y+ HLRR+RR A+++ +LR PA ++ GY LW+ELP+ +DA EL Sbjct: 356 STRRYDAHLRRLRRQLAERKQQAWQTLLRHLPAEVKIHHNDSGYFLWLELPEQLDAGELS 415 Query: 427 RRSLALGITVAPGRIFAATNRYSHFIRLNYSYAWSKETEQALKLVGKLVEEL 478 ++L I++APG++F+ + ++ F R N ++ W + EQA+K +G L+ E+ Sbjct: 416 AKALEHLISIAPGKMFSTSGAWTRFFRFNTAWHWGEREEQAVKQLGSLIREM 467 >ydcR [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Eco Escherichia coli K12 Length = 468 Score = 384 bits (987), Expect = e-106, Method: Compositional matrix adjust. Identities = 192/471 (40%), Positives = 291/471 (61%), Gaps = 8/471 (1%) Query: 7 YKQFADQLAASIRDGVLRPGERIASVRIASQQHKVSVTTVVRAYELLESLGIIESQPQSG 66 Y+Q A+QL I G+ +PG+R+ S+R +S TV AY+LLES G I ++PQSG Sbjct: 4 YQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARPQSG 63 Query: 67 YFVREQPEAPPKPALRTTSREDHPAWQESTEVDVSRLVLATLKTIQQDGTVPLGSPYPNP 126 Y+V Q PK + +R++ VD++ + L+ + VP S +P+P Sbjct: 64 YYVAPQAIKMPKAPVIPVTRDE--------AVDINTYIFDMLQASRDPSVVPFASAFPDP 115 Query: 127 ALFPSHRLAQYAGRIARHASQSSVFDDLPPGHPELLRQIARRYLENGLKVDPEEIVITVG 186 LFP +L + ++++ A+ SV ++LPPG+ EL + IARRY G+ + P+EIVIT G Sbjct: 116 RLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYALQGITISPDEIVITAG 175 Query: 187 ATEAINLCLQAVARPGDTIAVETPTFYAMLHAIERLGMRALEIPTDPQRGIDVGALEERM 246 A EA+NL LQAV PGD + VE P FY L A+ERL ++AL + TD + GID+ ALE + Sbjct: 176 ALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELAL 235 Query: 247 KTQAIAACMVMPNFQNPLGFQMPDSEKERLVRLAEQHQMPVIENAVYSELYYGNAHPSSL 306 + + AC +M N QNPLGF + +K +LV L Q+ + +IE+ VYSELY+G P Sbjct: 236 QEYPVKACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLPA 295 Query: 307 KNYDRDGLVLHCSSFSKSLTSAYRIGWAMPGRYRAQVEKLKFLNTLATPTAPQRAIAEYL 366 K +DR VLHCSSFSK L +RIGW G++ ++++L+ ++TL+T + Q A+ +YL Sbjct: 296 KAWDRHDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYL 355 Query: 367 TQGGYERHLRRVRRAFAQQRDMMRHFVLRFFPAGTQVSEPQGGYVLWVELPQGVDAMELY 426 + Y+ HLRR+RR A+++ +LR+ PA ++ GY LW+ELP+ +DA EL Sbjct: 356 STRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHNDSGYFLWLELPEPLDAGELS 415 Query: 427 RRSLALGITVAPGRIFAATNRYSHFIRLNYSYAWSKETEQALKLVGKLVEE 477 +L I++APG++F+ +S F R N ++ W + EQA+K +GKL++E Sbjct: 416 LAALTHHISIAPGKMFSTGENWSRFFRFNTAWQWGEREEQAVKQLGKLIQE 466 >ECs2043 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Ecs Escherichia coli O157:H7 Length = 468 Score = 384 bits (985), Expect = e-106, Method: Compositional matrix adjust. Identities = 192/471 (40%), Positives = 291/471 (61%), Gaps = 8/471 (1%) Query: 7 YKQFADQLAASIRDGVLRPGERIASVRIASQQHKVSVTTVVRAYELLESLGIIESQPQSG 66 Y+Q A+QL I G+ +PG+R+ S+R +S TV AY+LLES G I ++PQSG Sbjct: 4 YQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARPQSG 63 Query: 67 YFVREQPEAPPKPALRTTSREDHPAWQESTEVDVSRLVLATLKTIQQDGTVPLGSPYPNP 126 Y+V Q PK + +R++ VD++ + L+ + VP S +P+P Sbjct: 64 YYVAPQAIKMPKVPVIPVTRDE--------AVDINTYIFDMLQASRDPSVVPFASAFPDP 115 Query: 127 ALFPSHRLAQYAGRIARHASQSSVFDDLPPGHPELLRQIARRYLENGLKVDPEEIVITVG 186 LFP +L + ++++ A+ SV ++LPPG+ EL + IARRY G+ + P+EIVIT G Sbjct: 116 RLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYALQGITISPDEIVITAG 175 Query: 187 ATEAINLCLQAVARPGDTIAVETPTFYAMLHAIERLGMRALEIPTDPQRGIDVGALEERM 246 A EA+NL LQAV PGD + VE P FY L A+ERL ++AL + TD + GID+ ALE + Sbjct: 176 ALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELAL 235 Query: 247 KTQAIAACMVMPNFQNPLGFQMPDSEKERLVRLAEQHQMPVIENAVYSELYYGNAHPSSL 306 + + AC +M N QNPLGF + +K +LV L Q+ + +IE+ VYSELY+G P Sbjct: 236 QEYPVKACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLPA 295 Query: 307 KNYDRDGLVLHCSSFSKSLTSAYRIGWAMPGRYRAQVEKLKFLNTLATPTAPQRAIAEYL 366 K +DR VLHCSSFSK L +RIGW G++ ++++L+ ++TL+T + Q A+ +YL Sbjct: 296 KAWDRHDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYL 355 Query: 367 TQGGYERHLRRVRRAFAQQRDMMRHFVLRFFPAGTQVSEPQGGYVLWVELPQGVDAMELY 426 + Y+ HLRR+RR A+++ +LR+ PA ++ GY LW+ELP+ +DA EL Sbjct: 356 STRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHNDSGYFLWLELPEPLDAGELS 415 Query: 427 RRSLALGITVAPGRIFAATNRYSHFIRLNYSYAWSKETEQALKLVGKLVEE 477 +L I++APG++F+ +S F R N ++ W + EQA+K +GKL++E Sbjct: 416 LAALTHHISIAPGKMFSTGENWSRFFRFNTAWLWGEREEQAVKQLGKLIQE 466